bluuebunny/crossref_metadata_2025 huggingface dataset:
Hardware Security in IoT Devices with Emphasis on Hardware Trojans
Authors: Sidhu Simranjeet , Mohd Bassam J. , Hayajneh Thaier
Published: August 2019

Security of IoT devices is getting a lot of attention from researchers as they are becoming prevalent everywhere. However, implementation of hardware security in these devices has been overlooked, and many researches have mainly focused on software, network, and cloud security. A deeper understanding of hardware Trojans (HTs) and protection against them is of utmost importance right now as they are the prime threat to the hardware. This paper emphasizes the need for a secure hardware-level foundation for security of these devices, as depending on software security alone is not adequate enough. These devices must be protected against sophisticated attacks, especially if the groundwork for the attacks is already laid in devices during design or manufacturing process, such as with HTs. This paper will discuss the stealthy nature of these HT, highlight HT taxonomy and insertion methods, and provide countermeasures.
A Matrix Factorization Algorithm for Efficient Recommendations in Social Rating Networks Using Constrained Optimization
Authors: Ampazis Nicholas , Emmanouilidis Theodoros , Sakketou Flora
Published: August 2019

In recent years the emergence of social media has become more prominent than ever. Social networking has become the de facto tool used by people all around the world for information discovery. Consequently, the importance of recommendations in a social network setting has urgently emerged, but unfortunately, many methods that have been proposed in order to provide recommendations in social networks cannot produce scalable solutions, and in many cases are complex and difficult to replicate unless the source code of their implementation has been made publicly available. However, as the user base of social networks continues to grow, the demand for developing more efficient social network-based recommendation approaches will continue to grow as well. In this paper, following proven optimization techniques from the domain of machine learning with constrained optimization, and modifying them accordingly in order to take into account the social network information, we propose a matrix factorization algorithm that improves on previously proposed related approaches in terms of convergence speed, recommendation accuracy and performance on cold start users. The proposed algorithm can be implemented easily, and thus used more frequently in social recommendation setups. Our claims are validated by experiments on two real life data sets, the public domain Epinions.com dataset and a much larger dataset crawled from Flixster.com.
Nephrology Consultation for Severe SGLT2 Inhibitor-Induced Ketoacidosis in Type 2 Diabetes: Case Report
Authors: Nappi Felice , La Verde Antonietta , Carfora Giovanni , Garofalo Carlo , Provenzano Michele , Sasso Ferdinando Carlo , De Nicola Luca
Published: August 2019

Euglycemic diabetic ketoacidosis (euDKA) related to sodium-glucose cotransporter 2 inhibitor (SGLT2-I), despite being reported as consistent, though infrequent, adverse effect in all trials on SGLT2-I in type 2 diabetes mellitus (T2D), still remains poorly known in the real world. On the other hand, the use of this new class of antihyperglycemic agents is expected to increase based on the recent solid evidence of remarkable cardiorenal protection. Therefore, improving awareness on risk factors, diagnosis, and treatment of euDKA is essential to allow correct implementation of SGLT2-I in clinical practice. We here report a T2D patient admitted to the emergency department and then transferred to the nephrology-dialysis unit because of severe euglycemic diabetic ketoacidosis (euDKA) related to sodium-glucose cotransporter 2 inhibitor (SGLT2-I). In our patient, a concurrent acute kidney injury at presentation, initially attributed to excessive use of nonsteroid anti-inflammatory agents, and the absence of severe hyperglycemia led to delayed diagnosis and proper therapy. The detailed description of decision-making process for diagnosis and therapy, and the analysis of precipitating factors as well, discloses the helpful contribution of nephrologist to optimize prevention and management of euDKA.
Association between SNPs of Circulating Vascular Endothelial Growth Factor Levels, Hypercholesterolemia and Metabolic Syndrome
Authors: Salami Ali , El Shamieh Said
Published: August 2019

Background and Objectives: Four single nucleotide polymorphisms (SNPs); rs6921438 and rs4416670 in LOC100132354-C6orf223, rs6993770 in ZFPM2, and rs10738760 in VLDLR-KCNV2 were reported to explain up to 50% of the heritability of vascular endothelial growth factor circulating levels. These SNPs were also studied for possible associations with circulating lipid levels in supposedly healthy European individuals and in a limited number of Iranian individuals with metabolic syndrome. To go further, the association of those four SNPs with plasma lipid parameters, hypercholesterolemia and metabolic syndrome (MetS) was assessed. Materials and Methods: A cross-sectional study was conducted on 460 individuals chosen from the general population. Demographic and clinical data were collected and DNA was extracted and genotyped using Kompetitive allele specific PCR (KASP™). A meta-analysis followed, combining our participants with the Iranian individuals (n = 336). Results: Whereas rs10738760 was associated with total cholesterol (Tchol) (p = 0.01), rs6993770 showed significant associations with both Tchol and low-density lipoprotein cholesterol (LDL-C) levels (p = 0.007 and p = 0.01 respectively). Using a multivariate logistic regression model adjusted for different confounding factors, we found that rs6993770 was associated with hypercholesterolemia, specifically high Tchol (p = 0.01) and LDL-C levels (p = 0.01). Furthermore, rs10738760 was positively associated with the risk of MetS in these individuals (p = 0.02) and in the meta-analysis (OR = 1.67, p = 0.01). Conclusion: Our results suggest that whereas rs6993770 in ZFPM2 was positively associated with hypercholesterolemia, rs10738760 (VLDLR-KCNV2) has a possible implication in MetS in two Middle Eastern populations.
Galactoglucomannan Recovery with Hydrophilic and Hydrophobic Membranes: Process Performance and Cost Estimations
Authors: Al-Rudainy Basel , Galbe Mats , Lipnizki Frank , Wallberg Ola
Published: August 2019

In this study, we compared the GR51PP (hydrophobic/polysulfone) membrane with a series of hydrophilic (regenerated cellulose) membranes with the aim of increasing the retention of products and decreasing membrane fouling. The raw material used was a sodium-based spent sulfite liquor from the sulfite pulping process of spruce and pine. The results show that the hydrophilic membranes were superior to the hydrophobic membranes in terms of higher fluxes (up to twice the magnitude), higher product retentions and less fouling (up to five times lower fouling). The fouling was probably caused by pore blocking as observed in earlier studies. However, the hydrophilic membranes had a lower affinity for lignin, which was indicated by the lower retention and fouling. This also resulted in a separation degree, which was higher compared with the hydrophobic membrane, thus yielding a higher galactoglucomannan (GGM) purity. 2D HSQC NMR results show that no major structural differences were present in the hydrophilic and hydrophobic retentates. A techno-economical evaluation resulted in the RC70PP being chosen as the most cost-efficient membrane in terms of flux and product recovery.
Hot Workability of 300M Steel Investigated by In Situ and Ex Situ Compression Tests
Authors: Chen Rongchuang , Xiao Haifeng , Wang Min , Li Jianjun
Published: August 2019

In this work, hot compression experiments of 300M steel were performed at 900–1150 °C and 0.01–10 s−1. The relation of flow stress and microstructure evolution was analyzed. The intriguing finding was that at a lower strain rate (0.01 s−1), the flow stress curves were single-peaked, while at a higher strain rate (10 s−1), no peak occurred. Metallographic observation results revealed the phenomenon was because dynamic recrystallization was more complete at a lower strain rate. In situ compression tests were carried out to compare with the results by ex situ compression tests. Hot working maps representing the influences of strains, strain rates, and temperatures were established. It was found that the power dissipation coefficient was not only related to the recrystallized grain size but was also related to the volume fraction of recrystallized grains. The optimal hot working parameters were suggested. This work provides comprehensive understanding of the hot workability of 300M steel in thermal compression.
Use of the Swebrec Function to Model Particle Size Distribution in an Industrial-Scale Ni-Co Ore Grinding Circuit
Authors: Coello-Velázquez Alfredo L. , Quijano Arteaga Víctor , Menéndez-Aguado Juan M. , Pole Francisco M. , Llorente Luis
Published: August 2019

Mathematical models of particle size distribution (PSD) are necessary in the modelling and simulation of comminution circuits. In order to evaluate the application of the Swebrec PSD model (SWEF) in the grinding circuit at the Punta Gorda Ni-Co plant, a sampling campaign was carried out with variations in the operating parameters. Subsequently, the fitting of the data to the Gates-Gaudin-Schumann (GGS), Rosin-Rammler (RRS) and SWEF PSD functions was evaluated under statistical criteria. The fitting of the evaluated distribution models showed that these functions are characterized as being sufficiently accurate, as the estimation error does not exceed 3.0% in any of the cases. In the particular case of the Swebrec function, reproducibility for all the products is high. Furthermore, its estimation error does not exceed 2.7% in any of the cases, with a correlation coefficient of the ratio between experimental and simulated data greater than 0.99.
Impact of the Position of the Chemically Modified 5-Furyl-2′-Deoxyuridine Nucleoside on the Thrombin DNA Aptamer–Protein Complex: Structural Insights into Aptamer Response from MD Simulations
Authors: Seelam Prabhakar Preethi , A. Manderville Richard , D. Wetmore Stacey
Published: August 2019

Aptamers are functional nucleic acids that bind to a range of targets (small molecules, proteins or cells) with a high affinity and specificity. Chemically-modified aptamers are of interest because the incorporation of novel nucleobase components can enhance aptamer binding to target proteins, while fluorescent base analogues permit the design of functional aptasensors that signal target binding. However, since optimally modified nucleoside designs have yet to be identified, information about how to fine tune aptamer stability and target binding affinity is required. The present work uses molecular dynamics (MD) simulations to investigate modifications to the prototypical thrombin-binding aptamer (TBA), which is a 15-mer DNA sequence that folds into a G-quadruplex structure connected by two TT loops and one TGT loop. Specifically, we modeled a previously synthesized thymine (T) analog, namely 5-furyl-2′-deoxyuridine (5FurU), into each of the six aptamer locations occupied by a thymine base in the TT or TGT loops of unbound and thrombin bound TBA. This modification and aptamer combination were chosen as a proof-of-principle because previous experimental studies have shown that TBA displays emissive sensitivity to target binding based on the local environment polarity at different 5FurU modification sites. Our simulations reveal that the chemically-modified base imparts noticeable structural changes to the aptamer without affecting the global conformation. Depending on the modification site, 5FurU performance is altered due to changes in the local environment, including the modification site structural dynamics, degree of solvent exposure, stacking with neighboring bases, and interactions with thrombin. Most importantly, these changes directly correlate with the experimentally-observed differences in the stability, binding affinity and emissive response of the modified aptamers. Therefore, the computational protocols implemented in the present work can be used in subsequent studies in a predictive way to aid the fine tuning of aptamer target recognition for use as biosensors (aptasensors) and/or therapeutics.
Psoromic Acid, a Lichen-Derived Molecule, Inhibits the Replication of HSV-1 and HSV-2, and Inactivates HSV-1 DNA Polymerase: Shedding Light on Antiherpetic Properties
Authors: Hassan Sherif T. S. , Šudomová Miroslava , Berchová-Bímová Kateřina , Šmejkal Karel , Echeverría Javier
Published: August 2019

Psoromic acid (PA), a bioactive lichen-derived compound, was investigated for its inhibitory properties against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2), along with the inhibitory effect on HSV-1 DNA polymerase, which is a key enzyme that plays an essential role in HSV-1 replication cycle. PA was found to notably inhibit HSV-1 replication (50% inhibitory concentration (IC50): 1.9 μM; selectivity index (SI): 163.2) compared with the standard drug acyclovir (ACV) (IC50: 2.6 μM; SI: 119.2). The combination of PA with ACV has led to potent inhibitory activity against HSV-1 replication (IC50: 1.1 µM; SI: 281.8) compared with that of ACV. Moreover, PA displayed equivalent inhibitory action against HSV-2 replication (50% effective concentration (EC50): 2.7 μM; SI: 114.8) compared with that of ACV (EC50: 2.8 μM; SI: 110.7). The inhibition potency of PA in combination with ACV against HSV-2 replication was also detected (EC50: 1.8 µM; SI: 172.2). Further, PA was observed to effectively inhibit HSV-1 DNA polymerase (as a non-nucleoside inhibitor) with respect to dTTP incorporation in a competitive inhibition mode (half maximal inhibitory concentration (IC50): 0.7 μM; inhibition constant (Ki): 0.3 μM) compared with reference drugs aphidicolin (IC50: 0.8 μM; Ki: 0.4 μM) and ACV triphosphate (ACV-TP) (IC50: 0.9 μM; Ki: 0.5 μM). It is noteworthy that the mechanism by which PA-induced anti-HSV-1 activity was related to its inhibitory action against HSV-1 DNA polymerase. Furthermore, the outcomes of in vitro experiments were authenticated using molecular docking analyses, as the molecular interactions of PA with the active sites of HSV-1 DNA polymerase and HSV-2 protease (an essential enzyme required for HSV-2 replication) were revealed. Since this is a first report on the above-mentioned properties, we can conclude that PA might be a future drug for the treatment of HSV infections as well as a promising lead molecule for further anti-HSV drug design.
MOF-Confined Sub-2 nm Stable CsPbX3 Perovskite Quantum Dots
Authors: Li Zhenxing , Yu Chengcheng , Wen Yangyang , Wei Zhiting , Chu Junmei , Xing Xiaofei , Zhang Xin , Hu Mingliang , He Miao
Published: August 2019

The metal halide with a perovskite structure has attracted significant attention due to its defect-tolerant photophysics and optoelectronic features. In particular, the all-inorganic metal halide perovskite quantum dots have potential for development in future applications. Sub-2 nm CsPbX3 (X = Cl, Br, and I) perovskite quantum dots were successfully fabricated by a MOF-confined strategy with a facile and simple route. The highly uniform microporous structure of MOF effectively restricted the CsPbX3 quantum dots aggregation in a synthetic process and endowed the obtained sub-2 nm CsPbX3 quantum dots with well-dispersed and excellent stability in ambient air without a capping agent. The photoluminescence emission spectra and lifetimes were not decayed after 60 days. The CsPbX3 quantum dots maintained size distribution stability in the air without any treatment. Because of the quantum confinement effect of CsPbX3 quantum dots, the absorption and photoluminescence (PL) emission peak were blue shifted to shorter wavelengths compare with bulk materials. Furthermore, this synthetic strategy provides a novel method in fabricating ultra-small photoluminescence quantum dots.
The Synthesis, Structure, Morphology Characterizations and Evolution Mechanisms of Nanosized Titanium Carbides and Their Further Applications
Authors: Dong Bai-Xin , Qiu Feng , Li Qiang , Shu Shi-Li , Yang Hong-Yu , Jiang Qi-Chuan
Published: August 2019

It is widely known that the special performances and extensive applications of the nanoscale materials are determined by their as-synthesized structures, especially their growth sizes and morphologies. Hereinto, titanium carbides, which show brilliant comprehensive properties, have attracted considerable attention from researchers. How to give full play to their potentials in the light-weight manufacture, microwave absorption, electromagnetic protection, energy conversion and catalyst areas has been widely studied. In this summarized article, the synthesis methods and mechanisms, corresponding growth morphologies of titanium carbides and their further applications were briefly reviewed and analyzed according to their different morphological dimensions, including one-dimensional nanostructures, two-dimensional nanosheets and three-dimensional nanoparticles. It is believed that through the investigation of the crystal structures, synthesis methods, growth mechanisms, and morphology characterizations of those titanium carbides, new lights could be shed on the regulation and control of the ceramic phase specific morphologies to meet with their excellent properties and applications. In addition, the corresponding development prospects and challenges of titanium carbides with various growth morphologies were also summarized.
A Review of Virtual and Mixed Reality Applications in Construction Safety Literature
Authors: Moore H. Frank , Gheisari Masoud
Published: August 2019

Over the last decade, researchers have used virtual- and mixed-reality (VR-MR) techniques for various safety-related applications such as training, hazard monitoring, and preconstruction planning. This paper reviews the recent trends in virtual- and mixed-reality applications in construction safety, explicitly focusing on virtual-reality and mixed-reality techniques as the two major types of computer-generated simulated experiences. Following a systematic literature assessment methodology, this study summarizes the results of articles that have been published over the last decade and illustrates the research trends of virtual- and mixed-reality applications in construction safety while focusing on the technological components of individual studies.
Automatic evaluation of geospatial data quality using web services
Authors: M. A. Xavier Emerson , Ariza-López Francisco J. , Ureña-Cámara Manuel A.
Published: August 2019

El sector geomático vive un escenario de sobrecarga de datos donde casi todos los días se generan nuevas bases de datos geoespaciales (BDG). Sin embargo, hay poca o ninguna información sobre la calidad de estas BDG. En este contexto proponemos una solución para la evaluación automática de la calidad de los datos geoespaciales utilizando servicios web. Este enfoque está compuesto por procedimientos de evaluación automática para el control de calidad de la consistencia topológica, comple- ción y exactitud posicional según se especifican en el estándar brasileño. Algunos procedimientos de control requieren datos externos para fines de comparación. Por ello, en este trabajo, proporcionamos un conjunto de datos sintéticos generados según un diseño de experimentos con el objetivo de seleccionar los métodos más adecuados para encontrar correspondencias entre las BDG. La solución desarrollada tiene un capa de interoperabilidad que vincula usuarios y procedimientos automáticos utilizando la interfaz del Web Processing Service (WPS). Nuestros resultados mostraron que el procedimiento automático funcionó muy similar al manual.
Impacto socioeconómico por lahares y caída de ceniza ante la erupción del volcán Cayambe en la actividad florícola en Cayambe y Pedro Moncayo
Authors: Pavón Fernando , Andrade S. Daniel , Bernard Benjamin , Contreras Diana
Published: August 2019

El complejo volcánico Cayambe representa una potencial amenaza para poblaciones que basan su economía en la floricultura. En este trabajo, se presenta: 1) modelar espacialmente escenarios de erupción del volcán, 2) modelar espacialmente el potencial impacto de estos escenarios de riesgos por afectación de lahares y de ceniza; y 3) evaluar los impactos socioeconómicos de escenarios de erupción modelados por caída de ceniza mediante un análisis estadístico de simulaciones numéricas de escenarios eruptivos y zonas de afectación por lahares tomadas del nuevo mapa de amenazas del Cayambe. Así se determinó que espesores de ceniza de 20 a 50 mm serían el principal problema cubriendo el 81.46% de la superficie con pérdidas que ascienden los 300 millones de dólares en plantas e invernaderos. En el caso de lahares las pérdidas se darían en los suelos y se estiman pérdidas de 45 millones de dólares en el caso de lahares primarios y 15 millones de dólares en caso de lahares secundarios.Los resultados obtenidos en las simulaciones tienen mejor nivel de detalle que los obtenidos en años anteriores por la información cartográfica disponible del sector y las herramientas computacionales utilizadas; los mismos que concuerdan con los depósitos del Cayambe y pueden ser manejados para la toma de decisiones en beneficio de las poblaciones afectadas, considerando que una erupción del volcán Cayambe merece una atención especial por su alto impacto socioeconómico local y nacional por ser las exportaciones de flores un rubro importante para el país.
Análisis espectral y dispersión superficial de detritos suspendidos en la Bahía de Banderas mediante imágenes de satélite
Authors: González-Luna Carlos , , Filonov Anatoliy , Mireles Omar , Tereshchenko Iryna
Published: August 2019

Gracias a técnicas de colorimetría y métodos de clasificación no supervisada, pueden ser vectorizada y trazada la evolución de contaminantes vertidos en el mar con res- pecto al tiempo y al espacio, lo que, en la práctica, abarata el costo de investigación  y permite tener una mayor cobertura espacio-temporal. Este trabajo presenta el caso de estudio de Bahía de Banderas, Jalisco-Nayarit, México, donde se estudió el vertido de detritos por el río Ameca en el periodo 2006-2014 a través de un producto combinado de imágenes LandSat y Modis y con el análisis de las firmas espectrales de las diferentes bandas que presentan estos satélites se infiere los porcentajes de la materia orgánica disuelta en las plumas.
Membangun Pola Hidup Sehat Melalui Pemberdayaan dan Konsumsi Olahan Sayuran Sehat Menuju Desa Sehat Terpadu
Authors: Alifatin Aini , Harini Ririn , Raharjeng Erna Retnaning , Kurnadi Bambang
Published: August 2019

Tanpa mencerdaskan dan memberdayakan partisipasi dan peran masyarakat, upaya kesehatan sulit memberikan perubahan dan peningkatan kualitas sumber daya manusia. Pengembangan posyandu Balita dan Lansia, peningkatan terhadap ketahanan pangan,  peningkatan kesadaran masyarakat dengan kemandirian kader kesehatan, Pembuatan program reward keluarga sehat, Pembentukan sarana edukasi kesehatan melalui warung informasi, memberikan  harapan  penanaman  nilai perilaku hidup bersih dan sehat kepada semua kalangan, adalah  kegiatan utama  yang  dapat  meningkatkan kualitas SDM dalam ketahanan kesehatan. Menjadikan tradisi konsumsi sayur melalui posyandu Balita dan Lansia, akan menanamkan pola hidup sehat bagi keluarga. Sayuran organic menjadi daya tarik karena selalu di jadikan bonus bagi peserta yang hadir. Budidaya sumber alam (sayuran organic) selain sebagai unsur peningkatan gizi keluarga, juga mendukung perekonomian dalam bentuk penyadaran mastarakat akan  manfaat tanaman organic: budidaya sayuran dan tanaman organic berupa nuggetz sayur, bakso bayam, dan lain-lain. Budidaya tersebut dapat sekaligus meningkatkan perekonomian masyarakat melalui pelatihan packaging,  penyimpanan dalam freeser dan pemasaran baik melalui media online, social media maupun  menjalin networking dengan badan badan usaha di sekitar. Budidaya sumber alam (sayuran organic) dan pembentukan UMKM inilah yang akan menunjang ekonomi kesehatan keluarga. Desa Komis akan menjadi kawasan sehat, dan sentra pembangunan  kesehatan  serta peningkatan perekonomian warga sebagai hasil dari PKW Desa Sehat Terpadu.
THE ZONING OF SEVERAL
TERRITORIES OF THE SOUTH OF RUSSIA ACCORDING TO TOXOCARIASIS
Authors: Hutoryanina I.V. , Dumbadze O.S. , Shishkanova L.V. , Tverdohlebova T.I.
Published: August 2019

In recent decades, there is an increase in the number of toxocariasis morbidity rate in many countries. An
important role in the implementation of the infection's risk with toxocarosis is the state of contamination with
pathogens of epidemiologically significant environmental objects. Toxocara eggs are resistant to adverse environmental
factors and can persist in the soil for a long time. We presented data on seroepidemiological surveys
for toxocarosis of the population of the South of Russia (Republic of Adygea, Karachay-Cherkessia; Astrakhan
and Rostov regions, Krasnodar Krai) and results of soil sanitary-parasitological studies. The analysis of the
popula-tion morbidity with toxocarcosis in the Russian Federation showed the variability of its indicators
during different years. The basis for some territories zoning of the south of Russia for this helminth infection
was formed with toxocarosis morbidity rates, the results of a seroepidemiological survey of the population,
infection of dogs and soil contamination with toxocara eggs. According to the comparison of toxocariasis
morbidity data with the results of seroepi-demiological studies, we suggest that the true level of helminthiasis
morbidity in the South of Russia is much higher than officially registered. The results of the studies indicate
the need for caution in the aspect of the potential probability of population's toxocarosis infection.
MEASURES TO ENSURE
SANITARY-EPIDEMIOLOGICAL WELLBEING DURING THE PERIOD OF
PREPARATION AND HOSTING THE 2018 FIFA WORLD CUP
Authors: Andreeva E.E. , Istratov P.A. , Tagirova M.A. , Danilola M.N.
Published: August 2019

We presented the results of measures taken by the Moscow Office of Rospotrebnadzor to ensure sanitary and
epidemiological wellbeing during the preparation and hosting the 2018 FIFA World Cup (Championship):
providing control at all construction stages of sports facilities and sports infrastructure, including laboratory
and instrumental control of building, finishing materials and finished products.
The surveys of all involved in the Championship facilities, as well as within adjacent areas to especially
radiation-hazardous facilities in Moscow (National Research Center «Kurchatov Institute», National Research
Nuclear University «Moscow Engineering Physics Institute», Institute for Theoretical and Experimental
Physics named after A.I. Alikhanov of National Research Center «Kurchatov Institute», N.A. Dollezhal
Research and Development Institute of Power Engineering) were conducted in terms of ensuring radiation
safety. An examination of activities with sources of ionizing radiation was carried out; 21 sanitaryepidemiological
conclusions and 6 licenses on compliance with the above activities were issued.
HEALTH ASSESSMENT OF HEALTH WORKERS OF THE REPUBLIC OF TATARSTAN ON THE EXAMPLE OF FORENSIC MEDICAL EXPERTS
Authors: Il’ina O.A. , Shulaev A.V. , Timerzyanov M.I.
Published: August 2019

We analyzed the morbidity of chronic diseases of the employees of the Republican Bureau of Forensic Medicine of the Ministry of Health of the Republic of Tatarstan (RBFM MH RT) during 2016-2017. In the structure of employee morbidity during 2017–2018 the list of diseases is distributed by decreasing: diseases of the eye and its adnexa, the circulatory system diseases, the genitourinary system diseases, the nervous system diseases, respiratory diseases. Based on the research results there is a need to revise activity that focus on the prevention of occupational diseases to measures that promote to a strong commitment of health promotion and spreading the healthy lifestyle among employees.
90 years of PJSC “The Ukrainian Research Institute of Refractories named after A. S. Berezhnoy”
Authors: Martynenko V. V. , Primachenko V. V. , Kaznacheyeva N. M.
Published: August 2019

The article is devoted to the 90-th anniversary of the founding of PJSC “THE UKRAINIAN RESEARCH INSTITUTE OF REFRACTORIES NAMED AFTER A. S. BEREZHNOY”. At present, the Institute is the only one specialized scientific organization in Ukraine that develops and produces a uniqe, high-tech, competitive refractory products. The review of the developments carried out by the Institute over the last 5 years is presented.
Special vibrocast mullite-siliceous refractories with the given properties for glass melting furnaces
Authors: Martynenko V. V. , Primachenko V. V. , Shulik I. G. , Chaplianko S. V. , Tkachenko L. P.
Published: August 2019

Technologies have been developed for the production of special vibrocast large-sized mullite-siliceous and mullite-siliceous low-cement refractories with specified properties for the laying of side walls and the bottom of glass melting furnaces and other place of applications. The influence of the amount alumina and calcined kaolin fraction 3—0.5 mm on the properties of mass, raw and firing (at temperatures of 1350, 1400, 1450 оC) samples have been researched, and also the flow at vibration has been studied, stages of structure formation and technological factors, providing qualitative vibrocasting of products, have been determined. The developed mullite-siliceous and mullite-siliceous low-cement refractories in terms of properties fully meet the specified requirements: mass fraction of Al2O3 — 52.58 and 53.83 %, SiO2 — 46.11 and 45.19 %, CaO — 0.09 and 1.12 %, Fe2O3 — 1.10 and 1.06 %; apparent density — 2.21 g/cm3, open porosity — 20.2 and 20.3 %, cold crushing strength — 68 and 69 N/mm2, thermal conductivity (at 400—800 оC) — 1.237—1.637 W/(m ∙ K).
Investigation of phase transformations and crystallization features of mullite-cordierite materials, depending on the conditions of their heat treatment
Authors: Savvova О. V. , Logvinkov S. М. , Babich O. V. , Kurash L. S.
Published: August 2019

The features of the mullite-cordierite materials crystallization under conditions of heat treatment were investigated in the given work. Factors that determine the formation of a fine-dispersed volume-crystallized structure under conditions of a two-stage heat treatment to ensure a high level of mechanical and thermal strength of materials were established.
El concepto y la experiencia del «dolor» en las tesis de Macedonio Fernández y Vicente Fatone
Authors: Benavente Silvana Florencia
Published: August 2019

En este trabajo abordamos la noción de dolor en dos filósofos argentinos: Macedonio Fernández (1874-1952) y Vicente Fatone (1903-1962). En un primer momento, nos ocupamos de la crítica que emprende M. Fernández en torno a dos tipos de dolor, el
físico y el ontológico. En un segundo momento, atendemos a las configuraciones acerca del dolor que esboza V. Fatone a la luz de su interpretación de los preceptos budistas. Mencionamos dos concepciones acerca del dolor, el dolor con alcance ontológico –
budismo primitivo e Hînayâna–, y al dolor vinculado a la realidad empírica –Nâgârjuna–, dentro del budismo Mahâyâna-. Ambos pensadores plantean proyectos diversos en cuanto a la posibilidad de sustraerse al dolor, tanto desde una elaboración teórica como práctica. Tal es así que el paso por la experiencia del dolor tendrá lugar desde una atención sobre el cuerpo ya sea desde una analgesia del mismo, desde una serie de ejercitaciones metafísicas o desde operaciones de despojamiento de la realidad empírica.
¿Olvidar a Benjamin?: una polémica situada
Authors: Gillier Baptiste
Published: August 2019

En este estudio nos proponemos volver sobre la polémica que suscitó la publicación de un artículo de Beatriz Sarlo, en un número de la revista Punto de Vista de 1995, sobre los efectos nefastos de la divulgación universitaria de la obra de Walter Benjamin en la argentina, de la cual la autora participó activamente. Esta «moda Benjamin» –íntimamente ligada al boom de los Cultural Studies en su versión estadounidense de los años 80– provoca, según la autora, una inflación conceptual que agota la originalidad del pensamiento del filósofo alemán, y conduce a «usos bárbaros», como lo demuestra la multiplicación de los estudios sobre la figura del flâneur en contextos muy distintos del París fin-de-siècle. Mientras Beatriz Sarlo subraya la historicidad de las nociones benjaminianas, José Omar Acha por su parte señala en su artículo su potencialidad crítica.
Mujeres y filosofía en el campo intelectual del noroeste argentino
Authors: Sosa Paula Jimena
Published: August 2019

En general las historias de la filosofía en Argentina fueron desarrolladas desde la capital del país fundamentalmente por figuras masculinas a lo largo del siglo XX. Así, las narrativas en torno a la disciplina filosofía son escasamente permeables a la inserción de mujeres. El presente trabajo se propone desandar la «historiografía oficial» de las ideas filosóficas en Argentina introduciendo las propuestas desarrolladas por mujeres en Tucumán, en tanto polo cultural del noroeste argentino durante las décadas de 1940 y 1950. En este sentido, es posible pensar que sus desempeños intelectuales como figuras alejadas del centro cultural del país, posibilitaron el acceso a los debates filosóficos de su tiempo. Al mismo tiempo, consideramos que el noroeste es una región pionera en la inserción de las mujeres en el mundo académico y sus testimonios resultan novedosos para la construcción de un discurso historiográfico más complejo en torno al desarrollo de las ideas filosóficas en Argentina.
La obra de Dionisio Cañas en el hilo biográfico
Authors: Palacios Amador
Published: August 2019

El presente trabajo constituye una síntesis de mi libro Dionisio Cañas. Invitación a su obra. Biografía (Ciudad Real. Diputación Provincial, Biblioteca de Autores Manchegos, 2018). La producción de Dionisio Cañas es muy densa y numerosa. He sido obligado, por los límites de este artículo, a señalar solo unas cuantas obras de su extensa trayectoria, teniendo que omitir el comentario de muchas otras. Pero las que reseño pienso que son las más importantes en su andadura. Sí he querido recalcar, por un lado, las vicisitudes más decisivas, de cara a su escritura poética y sus acciones artísticas, de su transcurrir biográfico y, por otro, destacar su vasta formación intelectual subrayando los influjos más señeros en la construcción de su poesía, su literatura y su arte.
Kontribusi Kepemimpinan Situasional Kepala Sekolah, Upaya Meningkatkan Iklim Kerja Guru
Authors: Munahar Suhaili
Published: August 2019

This study aims to determine and analyze the contribution of situational leadership to school principals in an effort to improve the work climate of teachers. The subject population included 50 teachers from SMP Negeri 2 Sikur. This study uses a census study, with ex-post facto design. Data were analyzed by multiple regression and correlation analysis. The results showed that there was a positive and significant contribution between the principal's situational leadership in improving the teacher's work climate with a contribution of 62.5%. Therefore the principal's situational leadership on the work climate functions as a predictor of teacher performance in SMP Negeri 2 Sikur, East Lombok Regency.
Presentación del Dr. Roberto Esguerra Gutiérrez
Authors: Matijasevic Eugenio
Published: August 2019

Presentación del Dr. Roberto Esguerra Gutiérrez con motivo de la Primera “Conferencia Dr. Roberto Esguerra Gutiérrez”, dictada durante la inauguración del X Congreso SOLAMI – XXVI Congreso ACMI-ACP, Cartagena 18 de agosto de 2017

Tengo el honor de presentar al doctor Roberto Esguerra Gutiérrez. Honor bastante fácil de cumplir pues el Dr. Esguerra es una figura no solo bien conocida sino también bastante querida por todos aquellos, médicos y pacientes a la par, amigos y colaboradores, que hemos tenido la fortuna de trabajar con él; lo cual equivale, invariablemente, a aprender de él. Así que la presentación será breve
Una causa infrecuente de dolor de cuello: Síndrome de la apófisis odontoides coronada
Authors: Franco Jonathan , Robles Alba , Banguero Alexandra , Charte Angel
Published: August 2019

En la práctica clínica habitual existe un crecimiento en la demanda asistencial de servicios de urgencias. El dolor cervical es una patología muy frecuente que compete a diversos profesionales sanitarios. El síndrome de apófisis odontoides coronada, es una patología muy poco frecuente, que hace parte del espectro de las enfermedades por microcristales de pirofosfato cálcico, ocasionando una calcificación de ligamentos del proceso de odontoides cervical, llevando a una clínica de cervicalgia, fiebre y rigidez de nuca. Esta patología entra en el diagnóstico diferencial con patologías potencialmente graves. En muchas ocasiones lleva a procedimientos y gastos farmacológicos innecesarios, principalmente por el desconocimiento que la transforma en una patología infradiagnosticada.
Anuncios 43-4
Authors: De Medicina Interna Asociación Colombiana
Published: August 2019

Anuncios 43-4
Retos en investigación
Authors: Molina De Salazar Dora Ines
Published: August 2019

Editorial XXV Congreso Colombiano de Medicina Interna
Trabajos de Investigación Clínica
Authors: Insuasty Henríquez Jesús Solier , Alzate Gómez Diego Fernando , Castrillón Spitia Juan Daniel , Ordóñez Tatiana , Fernández-Mercado Juan Carlos , González C.A.
Published: August 2019

TIC-1 RENDIMIENTO DIAGNÓSTICO DE MARCADORES TUMORALES SÉRICOS CONVENCIONALES EN PACIENTES CON SOSPECHA CLÍNICA DE CÁNCER PRIMARIO O METASTÁSICO A HÍGADO (ARIAS FLÓREZ JUAN SEBASTIÁN, MARTÍNEZ DELGADO ANGÉLICA MARÍA, ALARCÓN TARAZONA MARTHA LILIANA, INSUASTY ENRIQUEZ JESÚS SOLIER, DIAZ MARTÍNEZ LUIS ALFONSO)

TIC-2 SATURACIÓN DE OXÍGENO EN PACIENTES CON NEUMONIA ADQUIRIDA EN LA COMUNIDAD (ALZATE GOMEZ DIEGO FERNANDO, BOLIVAR GRIMALDOS FABIO, FAJARDO RIVERO JAVIER, CORTES CANO MIGUEL ANGEL)

TIC-3 PRESCRIPCIÓN-INDICACIÓN DE LOS INHIBIDORES DE LA BOMBA DE PROTONES: COSTO DE LA PRESCRIPCIÓN INADECUADA EN UN PRIMER NIVEL EN COLOMBIA (CASTRILLÓN SPITIA JUAN DANIEL, AGUIRRE CARDONA MELISSA, CARDONA ECHEVERRI DIANA MARÍA, EMURA VÉLEZ MELISSA HIROMI, GARCÍA MAURNO MANUELA ALEJANDRA, GARCÍA OSPINA DIEGO ARTURO, GUTIÉRREZ OSORIO ELIANA ANDREA)

TIC-4 DESCRIPCIÓN DE PACIENTES CON ENFERMEDAD TROMBOEMBÓLICA VENOSA ADQUIRIDA EN EL HOSPITAL Y UTILIZACIÓN DE MEDIDAS ANTITROMBÓTICAS EN UN HOSPITAL UNIVERSITARIO (RUIZ PAULA, HERNÁNDEZ CATALINA, ORDOÑEZ TATIANA, BUITRAGO JOHANNA)

TIC-5 ESTUDIO DE UTILIZACIÓN DE HIPOGLUCEMIANTES EN LA POBLACIÓN CON DIABETES MELLITUS TIPO 2, DEL REGIMEN SUBSIDIADO EN SALUD DE LA COSTA ATLANTICA COLOMBIANA (JC FERNÁNDEZ MERCADO, L.T. ORJUELA RODRÍGUEZ, J.D. OSPINA MARTÍNEZ, M.A. AMÉZQUITA DELGADO)

TIC-6 COMPARACIÓN DE LA FILTRACIÓN GLOMERULAR MEDIDA POR IMAGEN DE RADIOISÓTOPOS Y LA ESTIMADA POR ECUACIONES BASADAS EN CREATININA (GONZÁLEZ CA, DURÁN A, VARGAS-CUERVO MT, GARCÍA PK, RODRÍGUEZ MP, CONTRERAS KM)
Ruptura espontánea del semitendinoso secundario al uso de una quinolona
Authors: Hennessey Calderón Diana Carolina , Severiche Bueno Diego Fernando
Published: August 2019

La ruptura espontánea de un tendón secundario al uso de una quinolona es un efecto adverso poco común, pero que con el paso de los años se ha venido documentado con mayor frecuencia. A pesar de lo anterior, aún no hay estudios clínicos que permitan aclarar su fisiopatología, qué estrategias pueden disminuir el riesgo de desarrollar una ruptura espontánea o a qué dosis de las diferentes quinolonas se aumenta el riesgo de presentar una ruptura espontánea. Adicionalmente, varías guías de práctica clínica incentivan el uso de las quinolonas como primera línea para el manejo de infecciones respiratorias o de vías urinarias sin hacer consideraciones sobre este efecto adverso.

Por lo anterior, presentamos a continuación el caso de un paciente de 31 años que posterior al inicio de ciprofloxacina para el manejo de una diarrea aguda presentó una ruptura espontánea del tendón del semitendinoso secundario al uso de la quinolona
Miocardiopatía periparto
Authors: Rojas Arias José Luis , Hincapie Porras Cristian , Muñoz Villa Manuela , Acuña Osorio Edgar Mariano , Vargas Diana , Diaz Alfonso Nidia Janneth , Molina Giraldo Saulo
Published: August 2019

La miocardiopatía periparto es una patología poco frecuente que puede conllevar a una alta tasa de mortalidad por el compromiso cardiaco si no se realiza un manejo oportuno y adecuado. Debido a su presentación clínica, las similitudes con síntomas propios del embarazo y aquellos generados por la preeclampsia, se convierte en un diagnóstico de exclusión que requiere de alta sospecha clínica. Se presenta el caso clínico de una paciente de 33 años de edad con diagnóstico de preeclampsia atípica, disfunción hepática, hematológica y renal en el puerperio, quien presentó evolución cardiovascular tórpida a pesar del manejo adecuado por lo cual se sospechó y objetivó el diagnóstico de miocardiopatía periparto que progresó a una falla cardiaca aguda con disfunción multiorgánica y necesidad de trasplante cardiaco
Sarcoidosis sistémica con afectación del tatuaje
Authors: Chavarriaga-Restrepo Andrés , Mesa-Navas Miguel Antonio
Published: August 2019

Se trata de una paciente que ingreso con síntomas pulmonares, asociado a uveítis, con infiltración del tatuaje. En quien se hizo el diagnostico de sarcoidosís sistémica con compromiso del tatuaje.
Tumor mesenquimal de mediastino
Authors: Gómez-Cerquera Juan Manuel , Cruz Valderrama Estefany Roxana
Published: August 2019

Varón de 40 años con cuadro clínico de 6 meses de dolor en hemitórax derecho, opresivo, intermitente, de intensidad moderada, asociado a disnea de medianos esfuerzos. En el examen físico destaca una disminución del murmullo vesicular en hemitórax derecho.

Se realiza radiografía de tórax (Figura 1) que evidencia una masa de 15 x 13 cm, bordes bien definidos, de localización extrapulmonar, que desplaza las estructuras mediastínicas. La tomografía axial computarizada de tórax (Figura 2) confirma los hallazgos; se realiza biopsia de la lesión y el estudio histopatológico concluye el diagnóstico de tumor mesenquimal fusocelular. El paciente es llevado a cirugía, logrando la resección total del tumor sin complicaciones (Figura 3).

Los tumores mesenquimales de mediastino son bastante raros y representan sólo un 2% de todos los tumores mediastínicos. La sintomatología suele ser muy variada, desde pacientes asintomáticos hasta síntomas severos principalmente si el efecto compresivo es importante.
Terapia Dirigida por Catéter con Fibrinólisis Local en Tromboembolismo Pulmonar de Riesgo Intermedio.
Authors: Orozco-Levi Mauricio , Mogollón-Vargas Melissa , Medina Libardo , Gorgadze Tamara , Cáceres Diana , Duarte Rubén , Ramírez-Sarmiento Alba Lucía , Saaibi José Federico
Published: August 2019

Introducción: En pacientes con tromboembolia pulmonar (TEP) aguda, la fibrinólisis arterial local puede tener una relación muy favorable entre beneficio y riesgo. Objetivo: Caracterizar las condiciones epidemiológicas y clínicas de los pacientes con TEP agudo de riesgo intermedio que han recibido indicación urgente de terapia fibrinolítica dirigida por catéter. Métodos: Estudio retrospectivo analítico de pacientes atendidos en la Fundación Cardiovascular de Colombia (período 2012-2016) con diagnóstico de TEP de riesgo intermedio llevados a terapia fibrinolítica mediante catéter pulmonar. Resultados: Se incluyeron 27 casos (26 pacientes, 57±20 años, 52% mujeres). La confirmación de embolia pulmonar aguda se realizó mediante angiotomografía. El 85% de los casos mostró disfunción ventricular derecha en ecocardiografía, en 74% elevación troponina, y en 82% elevación de BNP o pro-BNP. El tiempo puerta-aguja desde el diagnóstico hasta la fibrinólisis fue de 24 horas (RIQ, 43). El tratamiento endovascular incluyó alteplasa (dosis total, 47±18 mg) y fragmentación-aspiración mecánica mediante catéter pulmonar. El 78% de los pacientes mostró disminución de la PAPm >10% del valor inicial [i.e., respondedores, ∆PAPm=-27±11% (-9±5 mmHg)]. Cinco pacientes fueron no-respondedores (∆PAPm=-2±7%, -1±4 mmHg). La estancia en UCI fue de 7 días (1-19), y la hospitalaria 13 días (1-36). No se presentaron complicaciones por sangrado mayor ni de otra índole. La supervivencia a 90 días fue del 100%. Conclusiones: Esta serie demuestra que la fibrinólisis arterial pulmonar indujo una mejoría hemodinámica inmediata en una alta proporción de pacientes con TEP, con un balance beneficio-riesgo favorable y asumible en ausencia de complicaciones atribuibles inmediatas o tardías.
The tide is high, but it’s holding on: response of the grey bush-cricket, Platycleis albopunctata, to a storm surge
Authors: Gardiner Tim , Seago Bob
Published: August 2019

Coastal insects may be highly susceptible to population loss due to catastrophic inundation events. At two locations on the east coast of the UK (nature reserve and naturists’ beach), the response of the Nationally Scarce grey bush-cricket,Platycleis albopunctata, to the December 2013 storm surge was determined from long-term transect monitoring of stridulating males. In the post-surge seasons, males were more frequent on the back dunes, which would have been largely unsubmerged during the tidal event. Lower numbers ofP. albopunctatawere recorded on the fore dunes after 2013, probably due to submergence during the surge tide and extensive shingle deposition on its marram-grass,Ammophila arenaria, and open ground habitats smothering overwintering eggs. The heterogeneity of the dune habitat with slacks and ridges may render this species resilient to storm surges.
The renal transplant score: A different way of evaluating renal transplant pathology
Authors: Clauss R. P. , Kobryn A.
Published: August 2019

The renal transplant is a notoriously difficult organ to assess for pathology. Radionuclide imaging can help, but, although sensitive, the evaluation is not very specific. For this reason, a different approach was used to examine renal images and results were correlated with histology. The transplant score is determined from images of perfusion and function on certain criteria such as time of appearance of the kidney after tracer injection, intensity of background, size and homogeneity of tracer uptake by the kidney. Although small, the pilot study could distinguish between hyperacute rejection, acute rejection, chronic rejection and cyclosporin toxicity.
Letter to the editor: Whither breast imaging in SA
Authors: Markgraaf Chris , Sweetlove Ann
Published: August 2019

No abstract available.
Papillary carcinoma of the thyriod presenting as piriform fossa mass
Authors: Lau K. Y. , Ahuja A. T. , Ng C. F. , King W. , Metreweli C.
Published: August 2019

No abstract available.
Moyamoya disease presenting as an intraventricular haemorrhage in an adult African male
Authors: Silber E. , Szkup P. , Saffer D.
Published: August 2019

Moyamoya disease is a chronic non-inflammatory arteriopathy affecting vessels of the central nervous system, described rarely in non-Oriental populations.  We document this condition in a middle -aged African male with typical clinical and angiographic features and review the current literature.
The past, present and future of ultrasound
Authors: Corr Peter
Published: August 2019

No abstract available.
Attempted suicide by intravenous injection of mercury: A case report
Authors: Godinho S. , Sirkin L. L.
Published: August 2019

A 37 year-old male attempted suicide by intravenous injection of metallic mercury. Besides the embolization to the various organs, he suffered no ill-effects.
Pelvic hemangio-pericyptoma: A case report
Authors: Szkup P. , Saadia R. , Schlaphoff G.
Published: August 2019

A large pelvic hemangiopericyptoma causing intestinal obstruction is reported.
Intervertebral disc calcification in children
Authors: Magnus K. G.
Published: August 2019

Symptomatic cervical intervertebral disc calcification in children presents with characteristic signs and symptoms, and usually has a benign, self-limiting and predictable course. The radiological images of the spine likewise have typical appearances, with a recognisable pattern and following a predetermined course. A case report of this uncommon condition in an 8-year-old boy illustrates most of the clinical and radiological findings in this entity.