bluuebunny/crossref_metadata_2025 huggingface dataset:
Long‐Term Treatment Outcomes of the Elder Patients with Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma with Definitive Chemoradiotherapy or Radiotherapy
Authors: Liu Junqing , Li Yishuang , Chen Ying , Jiang Xue , Yu Haogang , Yan Senxiang
Published: July 2022

Background. Few randomized trials are available to guide clinical management of elderly patients with esophageal cancer. Therefore, treatment approaches for the elderly are challenging. Objective. We believe that chemotherapy and radiotherapy are more effective than radiotherapy alone. We envision that chemotherapy is more effective than radiotherapy alone in elderly patients with esophageal cancer. Methods. Retrospective data of patients aged 70 years and older from 2008 to 2015 at our institution were analyzed. Of 61 eligible patients, 32 received definitive CTR and 29 received RT alone. Progression‐free survival (PFS) was 16 months (range, 1–67 months), and the median overall survival was 19 months. Median PFS and OS in the chemoradiotherapy group were 17 months (95% confidence interval (CI), 15.1–24.8 months) and 22 months (95% confidence interval (CI), 20.4–32.7 months), respectively. Results. The median PFS and OS in the radiotherapy group were 16 months and 16 months, respectively. The OS rates at 1, 2, 3, and 5 years were 82%, 42.6%, 19.7%, and 6.6%, respectively. There was no difference in PFS between CRT and RT, but there was an advantage in OS for CRT. Positive nodules had an effect on PFS and OS. Conclusions. CRT is effective in elderly patients with nodal invasion of esophageal cancer. Higher radiation doses had an effect on PFS and OS, but there was no difference in PFS and OS between CRT and RT. Therefore, treatment approaches for the elderly are challenging.
Quantitative Evaluation and Path Optimization of College Students’ Employment Policy Based on Text Mining
Authors: Liu Yu , Li Ao
Published: July 2022

Based on the text mining method, the high-frequency word extraction of 20 policies to promote the employment of college students from 2015 to 2020 was carried out, and the key areas of concern of the policy texts were obtained, and the relationship between the policy priorities was visually displayed in the form of visual Knowledge Graph. On this basis, a PMC index model composed of 9 first-level indicators and 31 second-level indicators is constructed to quantitatively evaluate the employment policy of college students and select a representative policy P3 to draw the PMC surface map to trace the advantages and disadvantages of the secondary indicators of the policy and explore the path of policy optimization. The results show that the evaluation results of 19 of the 20 policies are acceptable or excellent, accounting for 95%, indicating that most of the current policies can effectively promote the employment of college students. However, representative policies can be optimized and upgraded according to two different ideas: “policy tendency-policy field-target-policy focus” and “policy tendency-policy field-policy effectiveness-policy focus-target-policy nature.”
New Topological Approaches to Rough Sets via Subset Neighborhoods
Authors: Dalan Yildirim Esra
Published: July 2022

This paper aims to obtain new types of approximations by using topological concepts. Firstly, different kinds of topologies are generated by subset neighborhoods and relationships between them are studied. Then, j‐subset approximations based on these topologies are introduced and their basic properties are examined. In addition to this, ‐near open and ‐open sets are defined and the connections among them are given. Later, new approximations are presented with the help of the aforementioned sets, and their main properties are investigated. Furthermore, the proposed approximations are compared both with themselves and with the previous one. From this, it is shown that the approximations based on ‐open sets are more accurate than those based on ‐open and ‐near open sets under arbitrary binary relation and than those based on j‐open sets under similarity relation. Finally, a real‐life problem related to COVID‐19 is addressed to highlight the importance of applying the proposed approximations.
[Retracted] Adoption of Dexmedetomidine in Different Doses at Different Timing in Perioperative Patients
Authors: Xie Jing , Feng Shiqiang , Qu Zhenhua
Published: July 2022

Dexmedetomidine (Dex) is an alpha‐2 agonist used for sedation during various procedures. Dex activates 2‐adrenoceptors, and causes the decrease of sympathetic tone, with attenuation of the neuroendocrine and hemodynamic responses to anesthesia and surgery; it reduces anesthetic and opioid requirements; and causes sedation and analgesia. Objective: it was to compare the perioperative effects of different doses of Dex at different timing in patients using Dex during the perioperative period adopting a medical data classification algorithm based on optimized semi‐supervised collaborative training (Tri‐training). Methods: 495 patients requiring surgical treatment in Xingtai People’s Hospital were randomly selected as the study subjects. The patients were divided into group A (used before induction), group B (used during induction), and group C (used after induction) according to different induction timing, with 165 cases in each group. Then, groups A, B, and C were divided into groups A1, B1, and C1 (0.4 μg/(kg·h) rate), groups A2, B2, and C2 (0.6 μg/(kg·h) rate), and groups A3, B3, and C3 (0.8 μg/(kg·h) rate) according to the dose used, with 55 cases in each group. Intraoperative anesthesia and postoperative adverse reactions were compared among the 9 groups. Results: the similarity between the Tri‐training algorithm optimized by Naive Bayes (NB) classification algorithm and the actual classification (93.49%) was clearly higher than that by decision tree (DT) and K‐nearest neighbor (kNN) classification algorithm (76.21%, 74.31%); heart rate (HR), systolic blood pressure (SBP), and diastolic blood pressure (DBP) values decreased obviously after Dex used in groups B1, C1, B2, C2, B3, and C3 (P <0.05), but did not change significantly in groups A1, A2, and A3 (P >0.05); the proportion of patients with satisfactory Ramsay score in group A3 was distinctly superior than that in groups A1, A2, B1, B2, B3, C1, C2, and C3 (P <0.05); the incidence of adverse reactions in group A3 was significantly inferior than that in groups A1, A2, B1, B2, B3, C1, C2, and C3 (P <0.05). Conclusion: the optimization effect of NB classification algorithm was the best, and the injection of Dex at the injection rate of 0.8 μg/(kg·h) before induction of anesthesia could apparently improve the fluctuation of HR, SBP, and DBP during perioperative period, and effectively reduce the occurrence of adverse reactions in patients, with better sedative effect on patients.