bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of Human Platelet-Rich Plasma and L-Ascorbic Acid on Morphology, Proliferation, and Chondrogenesis Ability towards Human Adipose-Derived Stem Cells
Authors: Rosadi Imam , Karina Karina , Rosliana Iis , Sobariah Siti , Afini Irsyah , Widyastuti Tias , Barlian Anggraini
Published: March 2019

Background: Microtia is a congenital malformation in the external ear due to cartilage defect. Adipose-derived stem cells (ADSC) is promising cells to develop cartilage tissue engineering for microtia. In this study, we focused on proliferation and chondrogenesis of ADSC in three different media, which consist of 10% fetal bovine serum (FBS), 10% FBS with L-ascorbic acid, and 10% human platelet rich plasma (PRP). Methods: ADSC were induced to differentiate into adipocytes, chondrocyte and osteocytes. ADSC morphology, proliferation and population doubling time was compared in three different media and analysed. Observation and alcian blue staining were done every 7 days to assess chondrogenic potency of ADSC from each treatment.Results: Isolated ADSC were able to differentiate into adipocytes, osteocytes and chondrocytes. ADSC in all group have fibroblast-like morphology, but cells in 10% FBS and 10% FBS with LAA group were flattened and larger. ADSC in 10% PRP group proliferates faster than 10% FBS with and without LAA. PDT values of ADSC were 34 hours, 44 hours and 48 hours, respectively for 10% PRP, 10% FBS with LAA and 10% FBS group. Alcian blue staining revealed that ADSC in 10% FBS with LAA and 10% PRP were able to proceed to chondrogenesis when cultured time were prolong up to 21 days, but not with ADSC in 10% FBS. Conclusion: We conclude that adding 10% FBS with LAA or 10% PRP into medium culture can support proliferation and chondrogenesis of ADSC. Key words: human ADSC, PRP, L-ascorbic acid, proliferation, chondrogenesis
Plasma Level of Umbilical Cord Hemeoxygenase-1 (HO-1) and Neonatal Outcome in Early Onset and Late Onset Severe Preeclampsia
Authors: Akbar Muhammad Ilham Aldika , Sari Indah Mayang , Ernawati Ernawati , Aditiawarman Aditiawarman
Published: March 2019

Background: Many studies had discovered that early onset severe preeclampsia (EO-PE) has worst maternal and neonatal outcome compared to late-onset type (LO-PE), related to its placental involvement. Severe preeclampsia was defined as newly onset severe hypertension developed after 20 weeks gestation in previously normal blood pressure women, with coexistence of proteinuria, or maternal organ or uteroplacental dysfunction. Hemeoxygenase-1 (HO-1) is an enzyme with multiple effect which is protective to pregnancy.Materials and Methods: The total study subjects were 40 pregnant women consisted of 10 EO-PE, 10 normal early onset pregnancy (EO-NP), 10 LO-PE, and 10 normal late onset pregnancy (LO-NP). As much as 5 cc of plasma from umbilical cord was taken as soon as the baby was born, and the HO-1 level was examined by enzyme-linked immunosorbent assay (ELISA). The primary outcome were umbilical cord HO-1 level and neonatal composite morbidity (low Apgar score, low birthweight, length of stay >5 day, respiratory distress syndrome, jaundice and neonatal death).Results: The plasma level of HO-1 in EO-PE subjects were lower than EO-NP (0.96±0.37 ng/mL vs. 2.43±0.58 ng/mL, p<0.001). There were no significant differences in the level of HO-1 in LO-PE and LO-NP (2.18±1.07 ng/mL vs. 3.02±0.64 ng/mL, p=0.277). Plasma level of umbilical cord HO-1 of EO-PE patients was lower compared to LO-PE (0.96±0.37 ng/mL vs. 2.18±1.07 ng/mL, p=0.034). Neonatal outcome of EO-PE was worse than EO-NP (p=0.033), and LO-PE (p=0.003), while in LO-PE did not different with LO-NP (p=0.211).Conclusion: EO-PE is associated with lower plasma umbilical cord level of HO-1 and worse neonatal outcome compared to LO-PE. This indicating abnormal placental blood vessel development, placental ischemia in EO-PE, lead to reduced uteroplacental perfusion and significantly worse neonatal outcome compared to LO-PE.Keywords: severe preeclampsia, early onset preeclampsia, late onset preeclampsia, hemeoxygenase-1
Impacts of Microbial Inoculants on the Growth and Yield of Maize Plant
Authors: Alori Elizabeth T. , Babalola Olubukola O. , Prigent-Combaret Claire
Published: March 2019

Background:

The use of microbial inoculants holds a great promise to improve crop yield without the negative environmental and health hazard associated with chemical fertilizer.

Aim:

To investigate ifPseudomonasspp. (Pseudomonas kilonensisF113 andPseudomonas protegensCHA0 strains) have promoting effects on vegetative growth and yield of different maize genotypes (viz. AFLATOXIN SYN 4W, TZB-SR, AFLATOXIN R SYN 2Y, AFLATOXIN SYN 3W and AFLATOXIN SYN-2Y) under different soil types.

Methods:

Both pot and field experiments were employed. Bacterialized seeds were sown (2 seeds/pot/stand).

Results:

Pot experiment showed that both the bacterial species significantly stimulated the growth of maize shoot length, stem girth, leaf length, root length and root weight. The effect of genotypes AFLATOXIN SYN 4W, TZB-SR, AFLATOXIN R SYN 2Y and AFLATOXIN SYN 3W are not significantly different from one another but AFLATOXIN SYN-2Y showed a significantly lower increase in the measured parameters. No significant difference was observed according to soil types. AFLATOXIN SYN 4W showed a significantly higher root weight while AFLATOXIN R SYN 2Y showed a significantly higher root length compared to the other maize genotypes. Moreover,Pseudomonassignificantly increased maize growth and yield under field experiment. AFLATOXIN R SYN 2Y and AFLATOXIN SYN 4W showed a significantly higher yield than the other maize genotypes studied.

Conclusion:

We concluded thatPseudomonas kilogenensisF113 andPseudomonas protegensCHA0 are potential biofertilizers.
r/Nipah: rapid creation of an online discussion space during a serious disease outbreak (Preprint)
Authors: Cole Jennifer , Ezziane Saphia , Watkins Chris
Published: March 2019

BACKGROUND

In previous health emergencies the people within the affected communities asked many questions at a time when professional medics and health agencies were overstretched and struggling to cope. Our previous research has shown that, during the 2014-15 West Africa Ebola Crisis, volunteer-moderated online discussion forums were able to provide peer-to-peer reliable, trustworthy and well-managed information. We speculated that with the right mix of epistemic and experiential knowledge, such a discussion forum could be set up rapidly during a future serious disease outbreak.

OBJECTIVE

The aim of this study was to set up a peer-to-peer health information exchange forum during a real outbreak of serious infectious disease in the shortest time possible. An outbreak of Nipah Virus in Kerala, India in May 2018 provided the opportunity to test our theories.

METHODS

We initiated a nipah virus discussion forum on the platform reddit.com, recruiting volunteer moderators from within the existing reddit community, thus facilitating posts and comments to the forum from genuine reddit users. We gathered and analyzed data on the number of posts (n=36) and comments (n=21) submitted, page views (n=840) during the period May 24 to June 23 2018 and subscribers (n=33) by utilising the data analysis tools embedded in the reddit platform.

RESULTS

We were able to set up a functioning health information exchange platform by May 24 2018 – within two weeks of the index case and one week of the official WHO verification of a nipah virus outbreak. Over the following five weeks, the forum received 36 posts, 840 page views (including 368 on the forum’s busiest day) and provided information in local languages spoken in the outbreak region as well as English. Information on government helpline numbers and FAQs was also provided to the community at risk.

CONCLUSIONS

The delivery of a fully functional discussion forum within a short space of time during an actual health emergency demonstrates that our theory that this is possible. Our theory that reddit could provide a suitable platform to host such a forum was upheld. This offers great potential for public health communication during future serious disease outbreaks.

CLINICALTRIAL

n/a
Health-Related Quality of Life Before and After Use of a Smartphone App for Adolescents and Young Adults With Cancer: Pre-Post Interventional Study (Preprint)
Authors: Pappot Helle , Assam Taarnhøj Gry , Elsbernd Abbey , Hjerming Maiken , Hanghøj Signe , Jensen Marc , Boisen Kirsten Arntz
Published: March 2019

BACKGROUND

Adolescent and young adult (AYA) patients with cancer are a group with underexplored needs throughout treatment and in survivorship. This missing knowledge can influence their quality of life (QoL). Given this fact, we have developed a smartphone app based on a cocreation process and have an investigation of QoL among users planned as part of pilot testing this app. Future research is warranted to determine the effect of mobile health (mHealth) tools such as smartphone apps among the AYA cancer population.

OBJECTIVE

The aim of this study was to investigate the feasibility of a smartphone app among AYA patients with cancer in active treatment and posttreatment, in a pilot test by measuring health-related QoL before and after the use of the app.

METHODS

Participants were recruited via the youth support initiative and social organization for AYAs with cancer, Kræftværket, based at Rigshospitalet, University Hospital of Copenhagen, Denmark. Participants were evenly distributed in active treatment and posttreatment groups. After written informed consent, all participants were asked to use the app Kræftværket as they deemed appropriate over a 6-week period. The participants were asked to complete the 30-item European Organization for Research and Treatment of Cancer Quality of Life Questionnaire before and after the 6-week period. The collected QoL data were analyzed with t tests to determine differences between groups and from baseline.

RESULTS

In total, we enrolled 20 participants, 10 in active treatment and 10 posttreatment (median time after treatment was 4 months) group. Median age of the participants was 25 years. No differences in QoL were seen at baseline (P=.65). The posttreatment group experienced a significant increase in overall QoL after the 6-week period (global QoL: baseline 62.5, SD 22.3; after 6 weeks 80.8, SD 9.7; P=.04). For the group in active treatment, the QoL remained stable throughout the 6 weeks.

CONCLUSIONS

This study shows the feasibility and possible effect on QoL associated with the use of an mHealth tool in AYA patients. mHealth support tools are warranted for this population.
What Players of Virtual Reality Exercise Games Want: Thematic Analysis of Web-Based Reviews (Preprint)
Authors: Farič Nuša , Potts Henry W W , Hon Adrian , Smith Lee , Newby Katie , Steptoe Andrew , Fisher Abi
Published: March 2019

BACKGROUND

Physical activity (PA) is associated with a variety of physical and psychosocial health benefits, but levels of moderate-to-vigorous intensity PA remain low worldwide. Virtual reality (VR) gaming systems involving movement (VR exergames) could be used to engage people in more PA.

OBJECTIVE

This study aimed to synthesize public reviews of popular VR exergames to identify common features that players liked or disliked to inform future VR exergame design.

METHODS

We conducted a thematic analysis of 498 reviews of the 29 most popular exergames sold in the top 3 VR marketplaces: Steam (Valve Corporation), Viveport (Valve Corporation), and Oculus (Oculus VR). We categorized reviews as positive and negative as they appeared in the marketplaces and identified the most common themes using an inductive thematic analysis.

RESULTS

The reviews were often mixed, reporting a wide variety of expectations, preferences, and gaming experiences. Players preferred highly realistic games (eg, closely simulated real-world sport), games that were intuitive (in terms of body movement and controls), and games that provided gradual increases in skill acquisition. Players reported feeling that they reached a high level of exertion when playing and that the immersion distracted them from the intensity of the exercise. Some preferred features included music and social aspects of the games, with multiplayer options to include friends or receive help from experienced players. There were 3 main themes in negative reviews. The first concerned bugs that rendered games frustrating. Second, the quality of graphics had a particularly strong impact on perceived enjoyment. Finally, reviewers disliked when games had overly complex controls and display functions that evoked motion sickness.

CONCLUSIONS

Exergames prove to be a stimulating avenue for players to engage in PA and distract themselves from the negative perceptions of performing exercise. The common negative aspects of VR exergames should be addressed for increased uptake and continued engagement.
The #MeToo Movement in the United States: Text Analysis of Early Twitter Conversations (Preprint)
Authors: Modrek Sepideh , Chakalov Bozhidar
Published: March 2019

BACKGROUND

The #MeToo movement sparked an international debate on the sexual harassment, abuse, and assault and has taken many directions since its inception in October of 2017. Much of the early conversation took place on public social media sites such as Twitter, where the hashtag movement began.

OBJECTIVE

The aim of this study is to document, characterize, and quantify early public discourse and conversation of the #MeToo movement from Twitter data in the United States. We focus on posts with public first-person revelations of sexual assault/abuse and early life experiences of such events.

METHODS

We purchased full tweets and associated metadata from the Twitter Premium application programming interface between October 14 and 21, 2017 (ie, the first week of the movement). We examined the content of novel English language tweets with the phrase “MeToo” from within the United States (N=11,935). We used machine learning methods, least absolute shrinkage and selection operator regression, and support vector machine models to summarize and classify the content of individual tweets with revelations of sexual assault and abuse and early life experiences of sexual assault and abuse.

RESULTS

We found that the most predictive words created a vivid archetype of the revelations of sexual assault and abuse. We then estimated that in the first week of the movement, 11% of novel English language tweets with the words “MeToo” revealed details about the poster’s experience of sexual assault or abuse and 5.8% revealed early life experiences of such events. We examined the demographic composition of posters of sexual assault and abuse and found that white women aged 25-50 years were overrepresented in terms of their representation on Twitter. Furthermore, we found that the mass sharing of personal experiences of sexual assault and abuse had a large reach, where 6 to 34 million Twitter users may have seen such first-person revelations from someone they followed in the first week of the movement.

CONCLUSIONS

These data illustrate that revelations shared went beyond acknowledgement of having experienced sexual harassment and often included vivid and traumatic descriptions of early life experiences of assault and abuse. These findings and methods underscore the value of content analysis, supported by novel machine learning methods, to improve our understanding of how widespread the revelations were, which likely amplified the spread and saliency of the #MeToo movement.
Pengujian Dampak Sistem Insentif Dan Orientasi Kognitif Terhadap Kinerja Kelompok: Studi Di Indonesia
Authors: Muslihah Siti , Tantri Sakina Nusarifa
Published: March 2019

This study aims to find out individual’s performance based on their cognitive orientation towards incentive system. This study refers to a previous study (Naranjo-Gil et al., 2012) that tested similarly that the study was conducted in Indonesia which has a different culture with the previous research’s origin country. This study used case study method with college student respondent that had economics background. The results of this study revealed that some conclusions. First, individual behavior in completing tasks tends to match with their cognitive orientation. Second, there was a difference between individualism cognitive orientation when they given to team-based structure incentive system. Third, there are differences in collectivism cognitive orientation groups when they given to an individual-based structure incentive system. The most appropriate incentive system used to improve the group performance which respect to the cognitive orientation group members is the team-based incentive system.
TESTING THE ROBUSTNESS OF THEORY OF PLANNED BEHAVIOR IN PREDICTING WOMEN’S INTENTION TO WEAR JILBAB
Authors: Siswomihardjo Sari Winahjoe , Sudiyanti Sudiyanti , Sutikno Bayu
Published: March 2019

For Muslim women, covering aurat has clearly been commanded in Al-Qur’an. Therefore, most Muslim women wear Jilbab to do so. Although Indonesia is the world’s largest Muslim country and in recent years, more fashionable Jilbab designs have been growing in Indonesian Muslim fashion market, yet, not all Muslim women wearing Jilbab. This study examines how well the Theory of Planned Behavior works in predicting Muslim women’s intention to wear Jilbab. This article proposes that Muslim women’s intentions to wear Jilbab are influenced by their attitude, subjective norms, perceived behavioral control, and together with perceived personal outcome. By using purposive sampling method, a representative national sample of 200 Indonesian Muslim women has been participated in a face-to-face survey about this topic. The findings confirmed the robustness of the Theory of Planned Behavior by indicating that both attitude and subjective norms significantly brought positive effect in predicting intention. Interestingly, the results demonstrated that perceived personal outcome and perceived behavior control appeared to be ineffective determinants. Therefore, the study result also slightly deteriorated the robustness of the Theory of Planned Behavior in the context of predicting Indonesian Muslim women’s intention to wear Jilbab. We present our findings, suggestions for future research, and potential limitations. The implications of this research for marketing practitioners are also discussed.
FOTO SEJARAH PADA MEDIA DIGITAL: PEWARNAAN DAN MEME BERKONTEN SEJARAH
Authors: Haeri Iman Zanatul
Published: March 2019

Technological developments make it easier for historical reviewers to approach historical sources. But there is a trend in Indonesian digital society to change historical sources such as historical photos as information consumption. Along with the development of the times, analog photos turned into historical photos that were present in the millennial era appeared in two ways; first coloring photo history, the second "meme" set in historical photos. In order to track digital footage of this phenomenon, historical methodology and photo analysis of Roland Barthes are used to show the birth of historical photo coloring trends and memes in the digital world. The coloring of historical photos causes a change in time awareness of historical sources and memes on historical photographs cause a change and multiplication of meanings in digital photos as historical sources.
Challenges and Preparedness of Pre-Service Teachers in a Globally Competitive Work Force
Authors: C. Batugal Maria Leodevina
Published: March 2019

This study explored on the pre-service teaching performance of the students of St. Paul University Philippines. To achieve this purpose data were obtained using a tool in evaluating classroom instruction among student-teachers. Data were analyzed using weighted mean and T-test for independent samples. The pre-service teachers’ performance was categorized into three areas namely; as a teacher, handling students’ class participation and other observations related to teaching. Results revealed that the performance of the pre-service teachers was generally Very Good. However, their choice and expression of words, ability to answer questions, ability to connect material to the broader aspect of the subject and their technique in asking questions were rated as Good. T-test results reveal that there is no significant difference in the teaching performance of the pre-service teachers when grouped according to gender and program of study. The research was also guided by an open-ended question to identify the weaknesses of the pre-service teachers. The weaknesses were identified such as: art of questioning, use of creative slide presentations, introducing reinforcement activities and handling students’ misbehavior. The result of this study will be a basis for introducing initiatives to improve the Teacher Education Program to lead pre-service teachers to become globally competent.
Los mam de México y Guatemala: un pueblo binacional entre la autonomía y la heteronomía
Authors: Toledo Pineda Miguel Angel Cristhian , Coraza de los Santos Enrique
Published: March 2019

En el presente artículo se realiza un acercamiento a los discursos y las prácticas de dos organizaciones del pueblo maya mam ubicadas en la región transfronteriza entre México y Guatemala. Por un lado está la asociación civil Conciencia Cultural Mam, en los municipios de Unión Juárez y Cacahoatán, Chiapas, y por el otro, el Consejo del Pueblo Mam de Sibinal, en el municipio de Sibinal, departamento de San Marcos. Se elabora una aproximación analítica considerando el surgimiento de las organizaciones, así como los objetivos que persiguen, desde las categorías de autonomía y heteronomía indígenas.
Los derechos sociales en las cadenas globales de producción: nuevas perspectivas para la negociación colectiva transnacional en la Declaración de Empresas Multinacionales (OIT)
Authors: Canalda Criado Sergio
Published: March 2019

Entre las nuevas formas de organización empresarial destaca la formación de las cadenas globales de producción. Este fenómeno productivo desborda no sólo los marcos nacionales desde el punto de vista jurídico sino que además transforma los marcos de relaciones laborales como los conocíamos hasta ahora, afectando los derechos sociales de los trabajadores.
Hacia un nuevo sistema de enjuiciamiento laboral
Authors: Esquinca Muñoa César
Published: March 2019

La Constitución de 1917 integró los derechos esenciales de los trabajadores y estableció en la fracción XX del artículo 123 a las Juntas de Conciliación y Arbitraje como órganos resolutorios. Su naturaleza la definió la Suprema Corte al considerarlas tribunales con plena jurisdicción para conocer y resolver conflictos individuales y colectivos de trabajo, en tanto que su integración, funcionamiento y competencia la regularon las leyes federales de 1931 y 1970.No obstante las múltiples reformas sufridas por el artículo 123, la fracción XX permaneció intocada hasta la de 24 de febrero de 2017, que sienta las bases de un nuevo sistema de enjuiciamiento con dos ejes rectores: obligación de patrones y trabajadores de asistir a la instancia conciliadora antes de acudir a los tribunales laborales, y solución de los conflictos por tribunales federales o locales, lo que implica la desaparición de las juntas.De
Contenido e importancia del expediente clínico. Acceso y confidencialidad
Authors: Kurczyn Villalobos Patricia
Published: March 2019

El siguiente artículo busca discernir sobre la importancia del derecho a la protección de datos personales y el carácter instrumental que éste tiene para el efectivo ejercicio del derecho a la salud. Lo anterior, a partir de la explicación de los alcances relativos al acceso y confidencialidad del expediente clínico, en sus modalidades física y electrónica, desde la óptica de la legislación aplicable, los criterios abordados al respecto en el ámbito judicial y administrativo, así como el planteamiento de oportunidades y desafíos por afrontar para eficientar su acceso y fortalecer la protección de datos personales.
Análisis de la tesis de jurisprudencia 97/2018 de la Segunda Sala de la Suprema Corte de Justicia de la Nación
Authors: Marquet Guerrero Porfirio
Published: March 2019

Como reiteradamente lo expresara Mario de la Cueva, reconocido como el mejor laboralista mexicano en el siglo XX, el Derecho del Trabajo entre otros caracteres es un Derecho inconcluso, en el sentido de que por su gran dinamismo está en constante evolución. Esta característica trasciende no sólo en el aspecto doctrinal, sino también en el normativo, incluidas las normas constitucionales, las legales y las contenidas en las convenciones colectivas de trabajo, así como también en los criterios elaborados por los órganos jurisdiccionales en la materia, de manera particular a través de la Jurisprudencia de la Suprema Corte de Justicia de la Nación.
Hubungan Pemeriksaan Kehamilan K4 dengan Kejadian Kehamilan Resiko Tinggi pada Ibu Hamil Trimester III
Authors: Bukit Rosmeri
Published: March 2019

A high-risk pregnancy is a pathological pregnancy that can affect the general state of the mother and baby. Early detection can be done on antenatal care service is by increasing coverage of antenatal care especially pregnancy examination ≥ 4 times or K4. The purpose of this study is to determine the relationship of pregnancy examination K4 with high risk of third trimester pregnancy at Harapan Raya Pekanbaru Health Center in 2014. The research quantitative type with analytical method, using cross sectional approach. Population of all pregnant women in the third trimester who conducted pregnancy checkup at the Puskesmas Harapan Raya total of 50 people. The sample size was 50 people with Total Sampling and statistical test using Chi square test. The results showed that obtained P value 0.001 where P value ≤ 0.005 Ho in rejection means there is a significant relationship. The conclusion of this study is that there is a relationship between the examination of pregnancy K4 with the incidence of high risk pregnancy trimester III.

Kehamilan resiko tinggi merupakan kehamilan patologi yang dapat mempengaruhi keadaan umum ibu dan bayi. Cara deteksi dini dapat dilakukan pada pelayanan antenatal care yaitu dengan peningkatan cakupan pelayanan antenatal khususnya pemeriksaan kehamilan ≥4 kali atau K4. Tujuan penelitian ini adalah untuk mengetahui hubungan pemeriksaan kehamilan K4 dengan resiko tinggi kehamilan trimester III di Puskesmas Harapan  Raya Pekanbaru tahun 2014. Jenis penelitian kuantitatif dengan metode analitik, menggunakan pendekatan cross sectional. Populasi seluruh ibu hamil trimester III yang  melakukan pemeriksaan kehamilan di Puskesmas Harapan Raya  jumlah 50 orang. Jumlah sampel  50 orang   dengan Total Sampling dan uji statistik menggunakan  uji Chi square. Hasil penelitian menunjukkan bahwa diperoleh P value 0,001 dimana P value ≤ 0,005 Ho di tolak artinya ada hubungan yang signifikan. Simpulan dari penelitian ini yaitu ada hubungan antara pemeriksaan kehamilan K4 dengan  kejadian kehamilan resiko tinggi trimester III.
Relato de acidente fatal causado por Bothrops jararaca (Serpentes: Viperidae) sem alterações hemorrágicas.
Authors: Meohas Tiago Gaudie Ley , Machado Claudio , Sana Rafael Zigliotti
Published: March 2019

Acidentes envolvendo serpentes peçonhentas são um problema de saúde pública no Brasil em virtude do desequilíbrio ecológico. O artigo relata acidente por B. jararaca apresentando edema e cianose, mas com TC normal. Evoluiu com taquicardia e hipotensão, recebendo 14 ampolas de soro antibotrópico. O paciente foi a óbito por choque cardiogênico decorrente da síndrome toxêmica. Apesar das manifestações locais compatíveis com envenenamento botrópico, a ausência de alteração no TC difere do padrão descrito pela literatura. Em função da baixa sensibilidade e especificidade deste teste, propõem-se que o parâmetro TC não deva ser utilizado de forma isolada para traçar conduta em acidentes botrópicos.
Relação entre mudanças climáticas e saúde humana
Authors: Uchoa NATALIA Macedo , Lustosa Romário Pinheiro , Uchoa Francisco Nataniel Macedo
Published: March 2019

Atualmente as pessoas têm relacionado problemas de saúde às mudanças climáticas de forma direta ou indireta, ocasionando o aumento da prevalência de certas doenças. Nessa perspectiva foi realizada uma revisão de literatura de 14 artigos que abrangem este assunto. A maior parte dos estudos indicou associação entre fatores do clima e desfechos na saúde humana. O objetivo deste artigo é dar a conhecer estudos desenvolvidos que revelam a associação entre o clima e a saúde humana. Observamos que ainda existem poucas pesquisas que relacionam mudanças climáticas e saúde e é de suma importância que novos estudos sejam realizados para melhor compreendermos este assunto.
Análise do potencial mutagênico do extrato etanólico de Zingiber officinale pelo teste do micronúcleo
Authors: Martins Breno Bezerra , Da Silva Judson Barroso , Dos Santos Millena Carine Oliveira Carvalho , Campos Priscila Karine Coelho , Maia Filho Antonio Luiz Martins , Monte Samylla Miranda , Marques Rosemarie Brandim
Published: March 2019

O Z. officinale é utilizado como condimento e erva medicinal desde a antiguidade, há mais de 3.000 anos, tendo sido usada para o tratamento de náuseas, dispepsias, vômito, diarreia e reumatismo. Apesar do uso corriqueiro de pela medicina popular, o gengibre não possui estudos acerca de sua genotoxicidade. O presente estudo teve como objetivo avaliar o potencial genotóxico do Z. officinale por meio do teste do micronúcleo. O estudo foi realizado com 25 camundongos fêmeas, divididos igualmente em cinco grupos. No grupo controle negativo, foi administrada a solução de água destilada aos animais. No grupo controle positivo, foi administrada ciclofosfamida (100 mg/kg). Nos grupos de tratamentos I, II e III, os camundongos receberam respectivamente 1.000mg/kg, 3.000mg/kg e 5.000mg/kg de extrato etanólico de Z. officinale. A genotoxicidade foi avaliada por meio da presença de micronúcleos em 2000 eritrócitos normocromados em sangue periférico. Os dados avaliados mostraram que o extrato etanólico de Z. officinale não possui atividade genotóxica.
Occurrence of the potent mutagens 2- nitrobenzanthrone and 3- nitrobenzanthrone in fine airborne particles
Authors: De Paula Guilherme
Published: March 2019

Occurrence of the potent mutagens 2- nitrobenzanthrone and 3-nitrobenzanthrone in fine airborne particles
Factors Affecting Specialty Choice Among Doctors Who Received Tuition Scholarships
Authors: Nguyen Bich-May , Bounds Gregory
Published: March 2019

Background and Objectives: The United States is projected to have a shortage of up to 46,000 primary care physicians by 2025. In many cases, medical students appear to select other specialties for financial reasons, including educational debt. Physicians who were part of two BS/MD programs and received full tuition and fee scholarships for college and medical school were surveyed to examine factors that may have impacted their specialty choice. This population of US students was selected because they do not have educational debt, so their choices could be examined independent of this influence.
Methods: One hundred forty physicians who graduated from the programs as of June 2013 were invited to complete a 32-question online survey. Descriptive statistics described the population. χ2 tests and nonparametric Wilcoxon rank-sum (Mann-Whitney) tests compared primary care and nonprimary care physicians as well as those initially interested in primary care who changed before medical school graduation versus those who went into primary care. Factor analysis and Student t-test examined trends among Likert scale questions.
Results: For the physicians for whom contact information was available, 74 (53%) responded. Out of 74 respondents, 18 (24%) went into primary care. Perceptions of family medicine, comments from faculty, and lifestyle played a role in deterring students from primary care.
Conclusions: Full tuition and fee scholarships alone were not associated with more students choosing primary care.
Performance stabilization of scintillation spectrometers for aerosol monitoring
Authors: Finkel Feliks , Krainukovs Igors , Litvinsky Vasily , Gostilo Vladimir
Published: March 2019

The article presents the results of the development of the scintillation gamma spectrometers, based on NaI(Tl), LaBr3 or SrI2(Eu) scintillators, intended for aerosol monitoring over a wide temperature range. The stabilization of the characteristics is provided by applying various stabilization methods of the spectrometric chain. The estimation of the impact of those methods on the stability of the characteristics of the developed radiation spectrometer is provided.
Computer non-iterative data acquisition of particle trajectory in a spark chamber
Authors: Poluzanski Vladimir , Zigic Aleksandar , Kovacevic Dragan , Nikolic Bosko
Published: March 2019

This paper presents a novel non-iterative algorithm for charge particle localization in a spark chamber. Its performance is evaluated by computer simulations using the Monte Carlo simulation method and compared with the performance of an appropriate iterative algorithm. It is found that the proposed non-iterative algorithm performs significantly better, is easier to implement and requires less computational resources than the iterative algorithm.
Sustainable Leadership in Multi Cultural Teams
Authors: Salih Ahmed , Salama Mohamed
Published: March 2019

The current shift towards digital transformation that guides the building blocks of the digital economy, has made it imperative to review some of the current theories, frameworks and paradigms. This applies to the different contexts of business management, where effective leadership is crucail, including project management and more so, sustainable project management. The authors’ current work, which is directed at both academics and practitioners, calls for a new paradigm in approaching Sustainable Leadership Effectiveness, that brings aspects from three knowledge domains (Anthropology, Sociology and Psychology) which are important for understanding human behaviors (in response to Murdock, 1971). The new paradigm and approach take leadership effectiveness practice, training and development into new dimensions, and embed them within an intelligent process with the Douglasian Cultural Framework (DCF)-based Cultural Intelligence at the center. Leaders focus should harness past and present experience to make a better future (Senge, 2008 cited in Tideman et al., 2013). This implies that for leadership to be considered sustainable, it must be formed around two important factors: adaptability and intelligence (Tideman, 2013). Accordingly, the journey that readers will be guided through in this chapter, is about novelty in thinking and practicing leadership which is different from the mainstream of leadership and Cultural Intelligence discourse and practice. The aim is to have managers and leaders not only understanding how to be effective, but how to behave intelligently in a challenging global context. In the introduction, the chapter presents the debate about leadership from the globalization lens, illustrating the obstacles that leadership research is facing. The chapter then provides the reader with a general review about Cultural Intelligence showing the dilemmas that the construct is facing, leading to the main theme of this chapter where the leadership adaptability framework is presented.
New Product Development, Implementing Agility through innovation and technology
Authors: Whistance-Smith Wallace , Salama Mohamed
Published: March 2019

New product development is an integral part of the project management practice. However, product design and process design have been, historically, two of the main components of the operations management theory. Operations management is the task of creating value in the form of goods and services by transforming inputs into outputs. More specifically, the techniques to create value are universal in scope and can be applied to any form of enterprise whether service-oriented or manufacturing-based. It is this operations transformation model that creates the possibility for enterprise success. The efficient production of goods and services requires an effective application of the transformative process, and it is in this transformation that value is created. Value supports the possibility for enterprise viability, and without such, there is little opportunity for sustained financial feasibility – this is particularly so in the ever-increasing competitive landscape of today’s worldwide economic system. This chapter discusses the fundamentals of product and service development, in the context of sustainable competitive advantage, in the era of digital transformation.
Sustainable Construction, Green Building Strategic Model
Authors: Salama Mohamed , Hana Ashraf
Published: March 2019

Academic and policy literature over the past four decades (from as early as the 1970s) has been, and still is, concerned with understanding and articulating the core principles of sustainable development and sustainable construction or, in other words, sustainable building and construction, which is a holistic, multi-disciplinary approach. The increasing global concern with the maintenance and improvement of the environment, as well as the protection of the human health has become an important aspect to be considered by construction companies worldwide. The chapter falls into two parts. The main aim of the first part is to present a critical review of the established theoretical frameworks in order to understand the topic in depth, and identify the main concepts and relevant dimensions or variables that have a crucial influence on promoting and implementing sustainable construction/green buildings practices. The second part presents the findings of a research study conducted by the authors (Salama and Hanna, 2013) that sought to develop a strategic model for implementing the green building initiative in the UAE; Green Building Strategic Model, (GBSM – UAE). Despite being based on the UAE case, the underpinning theoretical framework and the stages of modelling used in building, training and validating the model makes this section a useful read for all parties interested in the area of sustainable construction in general, and green buildings in particular, regardless of their geographical location.
The Mirror in Vedic India: Its Ancient Use and Its Present Relevance in Dating Texts
Authors: Parpola Asko
Published: March 2019

The major first part of the paper collects as exhaustively as possible all references to 'mirror' occurring in Vedic literature (c. 1200-300 BCE), and presents them with sufficient context in Sanskrit and English in order to show how and why the mirror was used in Vedic rituals and Vedic culture in general, and what meaning was ascribed to it. The second part of the paper discusses a fact of major significance that emerges from this recording: in the extensive older Vedic literature of the Saṃhitās, Brāhmaṇas and Śrautasūtras (excepting the late Kātyāyana-Śrautasūtra) there is no reference to the mirror at all. Therefore it seems likely that the mirror was not known in Vedic India until it was introduced to South Asia from the Persian Empire at the end of the sixth century BCE. The later Vedic literature, starting possibly with the Āraṇyakas, but definitely with the early Upaniṣads, postdates 500 BCE. So far we have lacked a similar firm date for Vedic literature.
Lope más allá del teatro: La Dorotea
Authors: Calvo Florencia
Published: March 2019

Introducción
La elegía y lo elegíaco en La Dorotea. Poética y desconsuelo
Authors: Calvo Florencia
Published: March 2019

Este artículo complementa una serie de trabajos anteriores en los que intento problematizar algunas cuestiones relacionadas con el género de La Dorotea en cruce con su momento de producción. Entendiendo ya agotadas de alguna manera las posibilidades de reflexionar acerca de la especificidad del sintagma “acción en prosa” postulo en estos acercamientos previos que la obra funciona como una geografía textual de la desintegración o de la ruptura. Desde este ángulo considero que se pueden sumar elementos para la definición de esta complicada ultima época del poeta, su extensamente analizada senectute, en tanto La Dorotea tendría mucho para decir no tanto tal vez en relación con su experiencia vital sino en relación con posicionamientos poéticos previos, con experimentaciones teóricas o como una forma de relativizar lo ya escrito antes de dejar de escribir. En este caso me interesa detenerme particularmente en lo que propongo llamar la poética del desconsuelo como territorio para explorar el manejo que el texto hace de los vectores propios del género elegíaco, con el objeto de ver si es posible establecer desde allí algunas conclusiones que colaboren en la intelección del universo lopiano.
Umbral, Francisco, Treinta cuentos y una balada, Edición de Bénédicte de Buron-Brun, Sevilla, Editorial Renacimiento, 2018, 260 pp.
Authors: Casado Marina
Published: March 2019

Reseña Umbral, Francisco, Treinta cuentos y una balada, Edición de Bénédicte de Buron-Brun, Sevilla, Editorial Renacimiento, 2018, 260 pp.
Manuel Gutiérrez Aragón, El ojo del cielo, Barcelona, Anagrama, 2018, 176 pp.
Authors: Salazar Landea Luz
Published: March 2019

Reseña Manuel Gutiérrez Aragón, El ojo del cielo, Barcelona, Anagrama, 2018, 176 pp.
Identificación de los Estilos de Aprendizaje: Estudiantes universitarios de entrenamiento deportivo de jornadas diurna y nocturna
Authors: Cardozo Luis Alberto , Molano-Sotelo Eric , Moreno-Jiménez Javier , Vera-Rivera Diana Andrea , Peña-Vega Mónica Astrid
Published: March 2019

Esta investigación pretende identificar y comparar los diferentes estilos de aprendizaje (EA) (Activo, Reflexivo, Teórico y Pragmático) en estudiantes del programa académico en Entrenamiento Deportivo en la Corporación Universitaria CENDA en Bogotá DC, utilizando el cuestionario “CHAEA”. Los resultados obtenidos se sometieron a análisis estadístico de características univariadas y bivariadas. Se aplicaron las pruebas de normalidad Kolmogorov-Smirnov y Shapiro-Wilk, donde únicamente el estilo activo reflejo una distribución normal (p>0.05); para analizar las diferencias de medias se utilizaron las pruebas T Student y U de Mann- Whitney, para analizar si existen diferencias entre los grupos se utilizó la prueba paramétrica de ANOVA de un factor (DMS) y no paramétrica de Kruskal-Wallis, y la correlación de Spearman. Se obtiene como resultado que en los estudiantes objeto de estudio prevalece el estilo Reflexivo y el Teórico en los semestres iniciales e intermedios, y los semestres finales tienen tendencia a lo reflexivo, teórico y pragmático, reflejando que suelen ser bastante analíticos, receptivos y exhaustivos en sus explicaciones, tendientes a la racionalidad y la objetividad, por tanto, muestran tendencias a lo metódico.
Annual Reviewer Acknowledgement
Authors: Editor Chief
Published: March 2019

The editorial team of the journal would like to thank the reviewers for their work in referring manuscripts during 2015.
Enhanced Cloud Security using Hybrid Mechanism of RSA, AES and Blowfish Data Encryption with Secure OTP
Authors: Singh Gurjeet , Garg Dr. Mohita
Published: March 2019

Cloud Computing has become one of the most talked about technologies in recent times and has got lots of attention from media as well as analysts because it is offering lots of opportunities. Enterprises have been determined to reduce computing costs and for that reason most of them started using it in IT technology then adapted virtualization technology. Cloud computing has revolutionized the way computing and software services are delivered to the clients on demand. It offers users the ability to connect to computing resources and access IT managed services with a previously unknown level of ease. Thus, security concerns among users of the cloud have become a major barrier to the widespread growth of cloud computing. In this research work, we have used the 3 step security mechanism for the keeping the data secure at the cloud. We have implemented the strong authentication mechanism using md5 encrypted OTP and enhanced the security of data using Cloud Broker and RSA, Blowfish and AES.  When you log on to your machine and then try to access a resource, say a file server or database, something needs to assure that your username and password are valid. With sensitive data stored in the cloud of the different users, we need a strong authentication mechanism along with OTP. Data breaches because of no/weak authentication. Afterwards we have verified the integrity of data stored at cloud provider using SHA2. Multiple parameters like processing time, processing cost, AES,RSA and blowfish encryption time, OTP generation and encryption time have been calculated and analyzed. We have been able to enhance the security by optimizing the processing time as well as processing cost. After implementing the proposed methodology, it has been summarized that the cloud security can be enhanced by applying the proposed mechanism. The proposed system has reduced the complexity, processing cost which increases the overall efficiency of the system.
Annual Reviewer Acknowledgement
Authors: Editor Chief
Published: March 2019

The editorial team of the journal would like to thank the reviewers for their work in referring manuscripts during 2012.
The Sociolinguistic Roles of Silence in Jordanian Spoken Arabic
Authors: Al-Harahsheh Ahmad Mohammad
Published: March 2019

The study of silence has not got much concern in the Arab world in general and in Jordanian Arabic in particular. The purpose of the current study is to seek to understand the practice and perception of silence in casual conversation in Jordanian society. Twelve dyadic conversations were conducted for 30 minutes each. The participants were 24 university students at Yarmouk University (Jordan-Irbid): twelve males and 12 females. They were categorised into two main groups: friends and strangers. Ninety seconds are analysed from the beginning, the middle, and the end of each conversation. The theoretical framework of this study draws on Turn-Taking system, ethnography of communication Speech Act Theory and Grice's Conversational. One of the more significant findings to emerge from this study is that silence is functional and meaningful in Jordanian society. It also has different interpretations in different contexts depending on the relationship between the interlocutors, the context of situation and the topic.
Language Contact, Use And Attitudes Among The Chaldo-Assyrians Of Baghdad, Iraq: A Sociolinguistic Study
Authors: Dweik Bader S. , Al-Obaidi Tiba A.
Published: March 2019

This study aimed at investigating the language situation among the Chaldo-Assyrians in Baghdad. The study attempted to answer the following questions: In what domains do the Chaldo-Assyrians of Baghdad use Syriac and Arabic? What are their attitudes towards both languages? To achieve the goal of this study, the researchers selected a sample that consisted of (135) Chaldo-Assyrians of different age, gender and educational background. The instruments used in this study were interviews and a questionnaire which comprised two different areas: domains of language use and language attitudes. The researchers concluded that the Chaldo-Assyrians in Baghdad used Syriac in different domains mainly at home, in religious settings and in their inner speech; and used it side by side with Arabic in many other social domains such as neighborhood, place of work, media and other public places. The study revealed that the attitudes of the Chaldo-Assyrians towards Syriac and Arabic were highly positive. Finally, the researchers recommended conducting similar studies on other ethnic groups in Baghdad like Turkumans, Kurds, Armenians and Sabians.