bluuebunny/crossref_metadata_2025 huggingface dataset:
Benefits of sacubitril/valsartan administration and physical training in cardiac rehabilitation: current trends and bibliometric analysis of the years 2015-2024
Authors: Iovanovici Diana Carina , Dogaru Bombonica Gabriela , Nistor – Cseppento Carmen Delia , Purza Anamaria Lavinia , Aur Cristina , Mocuta Diana , Behl Tapan , Bungau Simona Gabriela
Published: August 2024

Introduction. Heart failure, with its economic and social burden and increasing incidence in the general population, is a global problem. Since 2015, a new class of drugs with angiotensin and neprilysin re-ceptor inhibitory action, namely the combination of sacubitril and valsartan (S/V), has been introduced in the treatment of HF. The study aimed to perform a bibliometric analysis of the available knowledge and assess research trends through quantitative analysis of the literature related to the use of S/V and physical training in HF. Methods. In the study, we used the Web of Science database, period 2015-January 2024. The data obtained was processed with Vos viewer and Microsoft Excel. The results obtained and their interpretation provided an overview of the most relevant and prolific journals, countries, authors, and organizations. Conclusion. After marketing approval, the publication trend was upward until 2023, when the number of publica-tions decreased significantly. Our study shows that although the number of publications de-creased, updates of treatment guidelines were published, and a significant number of articles supporting the benefits of S/V treatment in chronic HF (with reduced or preserved ejection frac-tion) but also in acute forms were published. Although the number of articles on cardiac rehabilitation is low, this is highlighted in treatment guidelines and studies have emerged assessing the reasons why patients do not follow a cardiac rehabilitation programme. Cardiac rehabilitation is important for its physiological benefits: improving VO2max, myocardial blood flow and endothelial function. Health policies should be put in place to raise awareness of the importance of cardiac rehabilitation, including distances to a rehabilitation centre.

Keywords: sacubitril/valsartan; heart failure; cardiac rehabilitation; bibliometric analysis
Does the Impact Force Depend on Arm Position and Run-up Speed during Forward Handspring on the Vault in Elite Gymnasts? A Pilot Study
Authors: Veličković Petar , Stanković Dušan , Paunović Miloš , Đorđević Dušan , Bubanj Saša , Kocić Miodrag , Marović Božidar , Bjelica Bojan , Stanković Veroljub , Aksović Nikola
Published: August 2024

Background: This pilot study's aim was to examine the relationship between impact force, arm position and run-up speed, as well as to test new methods of measuring direct impact force on the vault while performing a forward handspring. (2) Methods: Data were collected from three elite, male artistic gymnasts (age 28.7±3.6 years, body weight 66.7±4.4kg; body height 169.7±3.2cm; experience 22±5.1 years), who performed two trials of the forward handspring. A high-speed camera, photocells and force plate were used to obtain and analyze the mechanical characteristics of the vault. Impact force (N), arm angle (degrees) and run-up speed (m/s) parameters underwent normality testing via the Shapiro-Wilks test, and bivariate correlations were used to explore relationships between them (p<0.05). (3) Results: Determined correlations between impact force and arm angle (r=0.02; p=0.97) and between arm angle and run-up speed (r=-0.45; p=0.37) have revealed non-significant relationship. Likewise, similar result was observed between impact force and run-up speed (r=0.44; p=0.38). (4) Conclusion: Non-significant correlations were observed, and new set-up (force plate-vault) for measuring maximal vertical impact force encountered in gymnastics vaulting showed consistent values with each vault performance, enabling researchers to measure the precise load magnitude..

Keywords: artistic gymnastics; technique; force, angle; speed; handspring
A Physical Fitness Perspective on Physical Education Lesson with Rampage Method Application
Authors: Doğru Zeki Can , Tutar Murat , İlhan Miray
Published: August 2024

: The purpose of this study is to investigate the effect of a program prepared in accordance with the Rampage method in physical education classes on the development of health-related physical fitness in children aged 9-12 (3rd-6th grade). Randomly selected control (n:30) and performance (n:34) groups were administered initial and final tests. SPSS 25.0 was used for statistical analysis. CG showed SLJ pre-test and post-test values of 106.33 ± 20.604 and 107.07 ± 18.94, respecti-vely, while PG exhibited pre-test and post-test values of 116.03 ± 19.983 and 123.71 ± 20.09 for SLJ. For the 20Meter run-ning test, CG had pre-test and post-test values of 15.23 ± 8.95 and 20.60 ± 9.06, whereas PG showed pre-test and post-test values of 18.59 ± 10.49 and 21.21 ± 10.10. Results of statistical analysis; A variable was found in the standing long jump measurements between the performance group(PG) and the control group(CG) (p<0.05). No significant difference was detected in the pre-test and post-test data for the other measured parameters. Based on these results, it is recommended to conduct comprehensive studies examining the effects of physical education classes prepared with the RAMPAGE method on children's physical fitness using different age groups or different physical fitness tests.

Keywords: Physical education, physical development, fitness
Exploring the Impact of Physical Inactivity on Digital Gaming Attitudes and Addiction among Secondary School Students
Authors: Kurhan Sebiha , Çar Bekir , Kurhan Cihad Onur , Kurtoğlu Ahmet , Eken Özgür , Polat Gülşen
Published: August 2024

The escalating concern regarding internet and digital game addiction among pre-adolescent children and its potential link to psychological issues prompted this study, aimed at evaluating digital game addiction levels and attitudes towards gaming in secondary school students. Conducted with a sample of 897 students from Ankara, Türkiye, the study employed a survey method, utilizing the "Attitude Scale towards Digital Game Addiction and Digital Games". Results indicated significant gender differences in addiction levels and attitudes, with boys showing higher scores. Age also played a role, with seventh graders exhibiting the lowest and eighth graders the highest addiction behaviors. Notably, those engaged in martial arts games and using consoles for gaming reported the highest addiction and positive attitude scores. The study underscores the prevalent issue of digital game addiction among youths, suggesting a strong correlation with physical inactivity. It concludes that promoting physical activity is essential not only for physical health but also as a preventative measure against the development of psychological issues stemming from digital game addiction.

Keywords: digital game addiction, adolescent psychology, physical inactivity, secondary school students, attitudes towards gaming, gender differences in gaming, gaming platforms, behavioral impacts of gaming
How much do disuse syndrome patients improve with convalescent rehabilitation? Assessment of improvement
Authors: Usuda Katsuo , Uesaka Takahiko , Okubo Takeshi , Shimada Takashi , Shimada Chieko , Ito Haruhide , Douko Norihito , Aoki Takuya , Takada Mayumi , Yokoyama Keiji , Shimizu Masahiro , Kitagawa Kengo , Itamoto Naoaki , Shimada Osami
Published: August 2024

The purpose of this study is to determined characteristics of FIM gain after rehabilitation for patients with disuse syndrome and what factors are beneficial for increasing FIM gain. The subjects were 168 patients (87 males and 81 females). We investigated the relationship between the degree of FIM gain and etiology, age, sex, gender, history of cerebrovascular disease, dementia, body weight, body mass index(BMI), hemoglobin, protein, albumin, prognostic nutritional index, malnutrition, and dysphagia. The primary etiologies that resulted in disuse syndrome were COVID-19, respiratory disease, gastrointestinal disease, urinary disease, cardiovascular disease, and others. The average FIM-total gain by age decreased as age in-creased. FIM-total gain was 8.0 for patients in their 90s. FIM-total gain was 13.8 for patients with no past incident of cerebrovascular diseases, 7.6 for one past incident, and 4.0 for two or more past incidents. FIM-total gain of the patients of severe dysphagia was significantly lower than that of the patients of normophagia / mild or moderate dysphagia. There was a mild correlation between FIM-total gain and gain of body weight (r=0.21) and between FIM-total gain and gain of BMI (r=0.21). Patients with disuse syndrome over 90 or with two or more incidents of cerebrovascular diseases should be treated, not in rehabilitation but in nursing care.

Keywords: Disuse syndrome; Rehabilitation; Malnutrition; Dysphagia; Functional independence measure (FIM)
Vitamin D Supplementation Improves Physical Performance in Athletes and Healthy Aging in Physically Active Adults
Authors: Hirsch Johannes , Cismaru Gabriel , Rosu Radu , Gusetu Gabriel , Comsa Horatiu , Caloian Bogdan , Irimie Diana , Fringu Florina , Tomoaia Raluca , Pop Dana
Published: August 2024

Vitamin D deficiency is a significant global public health issue, even in regions with all year sun exposure. Currently, the scientific community has not yet reached a unanimous agreement regarding the optimum levels of vitamin D and the precise threshold values. Additional efforts are required to standardize the evaluation of vitamin D insufficiency and deficiency and to provide uniform treatment guidelines. Epidemiological studies have identified a broad spectrum of estimated prevalences in athletes. Their performance when participating in sports. depend on their muscles, heart and lung function. It seems that athletes have significantly lower levels of vitamin D compared to the general population. However, there is a lack of comprehensive studies and systematic reviews on this subject, making it challenging to reach conclusions due to variations in laboratory techniques and cut-off values. While there is an abundant of research on the supplementation of vitamin D and its benefits, it is challenging to provide general recommendations for athletes due to the limitations of extrapolation. However, there is a rather high occurrence of Vitamin D deficiency among individuals who engage in regular physical activity. Supplementing with Vitamin D helps prevents osteoporosis, bone fractures, enhances muscle strength, avoids lung infections, heart failure, and arrhythmias. It is generally safe when used in appropriate quantities, given its wide therapeutic range. Athletes can decrease the occurrence of training dropouts caused by infection, arrhythmias, muscular weakness and potentially prevent the inability to participate in competitions through correct nutrition and vitamin D supplementation.

Keywords: vitamin D; sports; muscle; heart, athletes rehabilitation, vitamin D, ventricular premature contractions, physical activity
Analysis of oscillations of the center of pressure in postural control
Authors: Gherghel Carmen Liliana , Teodorescu Virgil , Iordan Daniel Andrei , Sardaru Dragos-Petrica , Onu Ilie
Published: August 2024

Posture results from intricate interactions between the central nervous system's control mechanisms, sensory integration, and musculoskeletal responses, encompassing two levels: sustaining tonic muscle activity for posture and making adjustments to maintain balance in response to disturbances. Due to its complexity, assessing posture with simple methods is challenging, necessitating the use of advanced techniques like stabilometric platforms to measure postural stability through the center of pressure oscillations, akin to an inverted pendulum concept, offering a comprehensive understanding of postural control mechanisms. Materials and Methods: The study aims to analyze the trajectory of the center of pressure (COP) in relation to the gender of the subjects, through directional indices (DI) and oscillation ratio (OR), in the process of posture maintenance. The study included a sample of 50 young subjects (21-24 years), sports practitioners, divided into two equal groups. Results: The study findings indicate that gender does not influence COP DI. However, there's a significant disparity between anteroposterior (AP) DI values (0.70) and mediolateral (ML) DI values (0.54). The results suggest a predominant reliance on AP control mechanisms for maintaining balance, regardless of gender. When visual input is absent, there's a slight increase in AP DI (0.72) and a decrease in ML DI (0.52), indicating a shift in balance strategies. In terms of OR, significant differences are observed based on gender, oscillation direction, and visual input. Female subjects exhibit higher AP OR (6.5) compared to males (5.1). Under closed eyes conditions, both genders show decreased AP OR (6.0 for females, 4.7 for males), indicating a reliance on alternative balance strategies in the absence of visual cues. Conclusion: The study highlights the complexity of postural control and empha-sizes the influence of factors like gender and visual input on postural stability metrics, providing valuable insights for further research and clinical practice. The analysis reveals that around 60% of COP oscillations occur in the AP direction, regardless of visual input changes. This underscores the critical role of AP control in maintaining balance, suggesting targeted interventions to enhance stability should prioritize this aspect.

Keywords: postural control, oscillations of the center of pressure, stabilometric platform.
Correlations Between Imaging and Clinical, Functional and Biological Features in Knee Osteoarthritis
Authors: Minea Mihaela , Vlădăreanu Liliana , Minea Alexandra-Elena , Andronache Iulia-Tania , Iliescu Mădălina-Gabriela
Published: August 2024

Background: For knee osteoarthritis (OA) pathogeny, cartilage damage is important, and ultrasonography (US) is helpful in assessing specific joint issues. Objectives: We intend to find correlations between functionality, pain level, serum glucose, cholesterol, triglycer-ides, uric acid, systemic inflammation and US findings for patients with knee OA. Meth-ods: For 50 consecutive subjects with symptomatic bilateral knee OA staged according to the scale Kellgren-Laurence(K-L) noted anamnestic data, Body Mass Index (BMI), func-tionality evaluated by Western Ontario and McMaster University Osteoarthritis Index (WOMAC) and pain’ intensity through Visual Analogue Scale (VAS). Using the US, the cartilage, meniscal and tendon changes, osteophytes, and fluid collections were assessed for 100 knee joints. SPSS 29.0.2.0 was used for statistical analysis. Results: In our group, with an average age of 60.54 years, there was observed a weak direct correlation between WOMAC and K-L grading (r=0.34) and a negative correlation between BMI and the carti-lage size on the external femoral condyle (r=-0.28). Its thickness on this site was directly correlated with lateral osteophyte severity. Smokers' injuries on the intercondylar groove were increased. Conclusion: Lateral femoral condyle cartilage thickness is inversely asso-ciated with BMI, and K-L grading directly correlates with dysfunctionality. The smokers had higher intercondylar cartilage injuries.

Keywords: Knee, osteoarthritis, pain, cartilage, ultrasonography.
Kinetic methods used in the postoperative recovery of a patient diagnosed with a puncture wound and foreign body retention in the middle third of the posterior face of the left forearm
Authors: Mucileanu Cezar , Spiridon Andra-Cristina , Turnea Marius , Rotariu Mariana , Condurache Iustina
Published: August 2024

Due to its superficial positioning, the muscle is more frequently exposed to trauma than bone or joint elements. Muscle injuries can occur either as a result of external forces, such as a traumatic agent, or internal forces that affect muscle function.
This paper presents a patient diagnosed with a puncture wound and retention of a for-eign body in the middle third of the posterior aspect of the left forearm, with its extraction following three surgical interventions. This type of injury presents an increased risk of af-fecting daily life activities.
The patient was functionally assessed post-operatively upon inclusion in the rehabili-tation program, during the program to observe progress, and at the end of kinetic treat-ment. The rehabilitation plan must be preceded by an adequate assessment, followed by setting goals according to the patient's needs and test results. Consequently, the patient rigorously followed the initial kinetic exercise plan established by the physiotherapist, leading to an improvement in muscle strength, joint mobility, and motor control. This re-sulted in an increase in the quality of life and social-professional reintegration.

Keywords: Osteoarthritis, knee, ultrasonography, cartilage, pain.
Non-pharmacological methods and techniques used in the therapy of children diagnosed with adhd. Study of literature
Authors: Condurache Iustina , Crăciun Iulia , Ilea Mihai , Rotariu Mariana , Mucileanu Cezar
Published: August 2024

Attention deficit and hyperactivity disorder (ADHD) is seen as a long-lasting and chal-lenging condition that affects various areas of life, such as academic and career success, relationships, and daily activities. Both the mind and the muscles jump from one task to another, failing to complete the activity, and thus difficulties arise in carrying out activities such as writing, tying shoelaces, riding a bicycle and more. Banal activities we would say, but essential for a normal lifestyle.
Medical recovery has a signifiant contribution in relieving symptoms and treating many pathologies, in both physical and mental relaxation. Moreover, it has been shown countless times that physical activity reduces stress, mainly based on muscle relaxation and improving cognitive and motor function through the development of neural functions. More and more children are diagnosed with this disorder, but, not enough attention is paid to these cases, which is one of the reasons why we chose to address this topic.
The paper aims to analyze studies carried out in recent years in different countries on motor impairments and other complications that can present children with ADHD, but also the way that balneophysiokinetotherapy has a positive effect in their therapy, being an essential form of therapy, alongside the psychological or medicinal one.
The studies analyzed confirm the benefits of physical exercise for children diagnosed with ADHD, showing visible effects on both the motor skills of the children and their lev-els of agitation and attention deficit. Although movement therapy is widely used in this condition, there are no protocols standardizing the type, duration, and intensity of exer-cise programs used. Occupational therapy, massage, and yoga have been noted for their beneficial effects on patients diagnosed with ADHD.

Keywords: ADHD, hyperactivity, therapy
A trans-generation conundrum with implications in rehabilitation programs – what factors influence non-specific back pain in children?
Authors: Vlădăreanu Liliana , Iliescu Mădălina Gabriela , Danteș Elena
Published: August 2024

Back pain in children and adolescents is one of the most frequent reasons for seeing a medical specialist worldwide. Many factors have been incriminated when it comes to influencing the appearance of non-specific back pain in children as well as in adults. For the younger population, some of the culprits seem to be sitting for long periods, us-ing harmful postural patterns, a forward head posture determined by incorrect positioning during prolonged studying hours, and carrying a too-heavy backpack, but do they really influence non-specific back pain in children? These ques-tions are valid for all generations and countries.
This paper aimed to review the published literature to determine whether the factors mentioned above, sitting in mismatched school furniture, carrying heavy backpacks, and forward head posture, influence the incidence of non-specific back pain in children and whether there are any data or differences between the general population and Roma-nian students. For this purpose, we conducted database research using the keywords “non-specific back pain in chil-dren, sitting, school furniture, forward head posture, backpack carrying” and various combinations of these terms, which returned 37 eligible articles for this paper in PubMed - Center for Biotechnology Information (NCBI) and Sci-enceDirect. There was no time limit on the researched articles, and they had to refer to the pediatric population, be open-access and in extenso articles, and be written in English, French, or Spanish.
After analyzing the results from these articles, the conclusion is that there is no evident or spe-cific connection between non-specific back pain in pediatric populations and harmful posture patterns while sitting or carrying a backpack. Also, more multicentered research using fewer variables and more objective measurement instruments is needed.

Keywords: non-specific back pain in children, sitting, bad posture, school furniture, forward head posture, back-pack carrying
Non-invasive neuromodulatory therapies applied in trigeminal neuralgia
Authors: Costescu Elena , Ciuhodaru Tudor , Calin Gabriela , Mihai Cozmin , Grierosu Carmen
Published: August 2024

Background: Estimates reveal that about 1 in 15,000 patients suffer from pain impulses from trigeminal neuralgia. Annually there are 5-6 new cases registered per 100,000 inhab-itants, with an increased frequency in women with a ratio of 3/2:W/M. It is revealed that the first manifestations appear at the ages between 40 and 60, but in recent decades cases have appeared at younger ages, starting even with 21. Given the high intensity of pain in the trigeminal pathology, significantly disabling pain for long periods of time, effective noninvasive approaches are required to reduce pain, reduce the frequency of exac-erbations and bring patients to a functioning state as close as possible to the physiological limit. Material and method: A low frequency pulsatile magnetic field is a non-pharmacological and non-invasive method which is widely used in a multitude of medi-cal conditions by medical and paramedical professionals for the management of chronic or acute pain. This original research aims to provide an insight view into the review of evi-dence available for the analgesic non-invasive therapy uses of the pulsed magnetic field. The before and after examinations the therapy have included a general assessment of the functional status, an assessment of pain severity. Result: With this study we hope to demonstrate the increased efficiency of the non-invasive rehabilitation methods with ap-plication in trigeminal neuralgia pathology that qualitatively affects the daily life of the pa-tients experiencing trigeminal neuralgia. Conclusion: Non-invasive rehabilitation in trigem-inal neuralgia registers remarkable results, similar to drug approaches, the major benefit being the absence of adverse effects both during treatment and late, in the long term. It in-creases the quality of life of patients, the frequency of relapses and the intensity of the pain-ful stimulus from the first treatment sessions..

Keywords: trigeminal, neuromodulation, pain, neuralgia, magnetotherapy, non-invasive
Pluridisciplinary approaches in global postural rehabilitation
Authors: Călin Gabriela , Costescu Elena , Damir Daniela Liliana , Mihai Cozmin , Grierosu Carmen , Ciuhodaru Tudor
Published: August 2024

The global postural imbalances relationship is frequently encountered in recent medical practice, requiring multidisciplinary approaches to bring patients to function as close as possible according to the physiological limit. About half of the world’s population experi-ences pain and dysfunction induced by postural imbalances during their lifetime. This re-port aimed to assess the nonpainfull and currative effect of the electropuncture technique complemented by massage and active postural kinetotherapy of global posture imbalances and acute or chronical pain at various levels. This research provide an insight into the re-port of evidence available for the analgesic uses of TENS in postural defects. Correlations regarding imbalances at various levels was found in various studies regarding analyze or diagnosis, without addressing the non-invasive multidisciplinary treatment. In these stud-ies, we are hoping to raise the non-invasive reabilitation treatment and increase their use in pathologies with involves global postural imbalances. The discomfort and pain experi-enced by people with generalized postural disorder on a daily basis can have a negative impact on quality of life and, if left untreated, can lead to significant worsening of the con-dition over time. Global rehabilitation with non-invasive and non-pharmacological meth-ods, without adverse effects, including electropuncture (TENS) applied to the refferal points in conjunction with proprioceptive kinetotherapy techniques, massage and psycho-therapy is the path to the success of occlusion-postural rehabilitation with significant re-sults on painful suffering global postural imbalances.

Keywords: global posture, postural imbalance, correlation, rehabilitation, multidisciplinary, electropuncture
Particularities of rhythm and conduction disorders in heart failure patients with preserved ejection fraction admitted to a rehabilitation hospital
Authors: Mihăilă Marius-Dragoș , Pop Dana
Published: August 2024

Background: The mortality and prognosis of patients with heart failure with preserved ejection fraction have shown minimal improvement over the past 20 years, possibly since this condition is often accompanied by various other cardiovascular risk factors and comorbidities, the correlation with various rhythm and conduction disorders being yet to be elucidated. (2) Methods: This study investigated 134 patients with heart failure with preserved and reduced ejection fraction, analyzing the presence and clinical impact of rhythm and conduction disorders in this groups of patients.; (3) Results: Atrial fibrillation is the most common arrhythmia in patients with heart failure with preserved ejection fraction and rhythm and conduction disturbances are significantly associated with essen-tial hypertension (p = 0,005) and chronic pulmonary heart disease (p = 0,016) in this pa-tients; (4) Conclusions: heart failure with preserved ejection fraction is an intensely ar-rhythmogenic condition that requires optimal treatment strategies which are adapted to the multiple possibly associated comorbidities.

Keywords: heart failure with preserved ejection fraction; atrial fibrillation; comorbidities; conduction disorders
Poststroke Spasticity: Pathophysiology and Management An Accurate Evaluation of Spasticity
Authors: Piseru Emanuel- Andrei , Piseru Teodora , Ignat Bogdan-Emilian , Grosu Cristina , Alexa Daniel , Cretu Raul Andrei
Published: August 2024

Stroke is a major contributor to long-term impairment and disability, affecting up to one-third of survivors and almost half of patients showing neurological deficit at six months. Spasticity affects approximately 25% of individuals within two weeks of a stroke and increases to 44% in patients who have had a second stroke. Severe or incapacitating spasticity affects 15% of post-stroke individuals. Poststroke spasticity is also linked to additional signs and symptoms of the upper motor neuron syndrome, such as simultaneous contraction of agonist and antagonist muscles, weakness of the muscles, and a lack of coordination. Spasticity arises due to aberrant neuroplasticity that develops after a stroke and there is currently no specific intervention method designed to address and correct this abnormal plasticity that takes place during the acute phase. Just before implementing any measures to deal with spasticity, it is crucial to evaluate the influence on the quality of life and level of severity. Several grading scales are used to measure spasticity such as the MAS and modified Tardieu scale.There are various therapeutic approaches that may be categorized into three main classes: physical, pharmaceutical, and surgical. Each class has a distinct purpose and is used at the appropriate moment to reduce the level of spasticity and improve the patient's health. Physiotherapy serves as a base of improving the patient's condition and facilitating the development of brain networks. The objective of post stroke spasticity management must include not only the reduction of muscle hypertonia, but also the evaluation of how post stroke influences functionality and overall mental health. Improper treatment or non-compliance may result in increased pain, joint contraction, and further disability. The goal is to assist the patient in achieving the best possible quality of life.

Keywords: Pathophysiology of Post-Stroke Spasticity; Management of Post-Stroke Spasticity; Evaluation of Post-Stroke Spasticity
New data about overlooked terricolous lichen-forming and lichenicolous fungi of Ukraine
Authors: Darmostuk Valerii , Sira Olha , Govorun Oleksandr
Published: August 2024

The new distribution data on rarely collected terricolous lichen species in Ukraine, Agonimia globulifera, Enchylium limosum, Epiphloea byssina, Gregorella humida, Sarcosagium campestre, Steinia geophana, Scytinium biatorinum, S. schraderi, and Verrucaria bryoctona, are provided. Notably, A. globulifera and S. biatorinum have been reported for the first time in the lowland part of Ukraine. Furthermore, the lichenicolous fungus Llimoniella terricola, growing on Epiphloea byssina, is reported for the first time in Eastern Europe. Descriptions, along with notes on similar species, habitat preferences, and general distribution, are provided for each species.
Prediction of uterine myoma growth rate: what's new? (Literature review)
Authors: Gladchuk I. , Salekh O.
Published: August 2024

Uterine fibroid remains a relevant issue in modern gynecology and reproductive medicine as the most common benign tumor of the female reproductive organs. Comprehensive diagnosis of the condition of the myomatous nodule and its potential growth rate plays a significant role in the rational selection of treatment tactics for women of reproductive age with uterine fibroids.
Objective. To study and analyze existing methods of diagnosis and prediction the growth of uterine fibroids.
Matherials and methods. Information search was conducted in the scientific literature in domestic and foreign publications, 46 sources were studied and analyzed. In the course of the study, a meta-analysis of the information obtained was carried out as to the set goal.
Results and discussion. At present, at least three main mechanisms of activation of signal pathways stimulating leiomyocyte to pathological growth and division have been elucidated: cytokines, growth factors, and hormone-dependent channels. All links in the activation of signal pathways affecting the cell, which subsequently lead to pathological proliferation and tumor transformation, are interconnected. In recent years, the pathogenesis of uterine fibroids has been actively studied not only at the tissue level but also at the genetic and epigenetic levels. It has been definitively proven that disturbances in microRNAs, both tissue-specific and stable, play a leading role in regulating the expression of key genes associated with the pathogenesis of uterine leiomyomas, both in tumor foci and in biological fluids. Conclusions. Study of the expression of microRNAs is a promising method for understanding the further development of the pathological process and for predicting the growth of uterine fibroids.
Reducing cardiovascular risk - are omega 3 fatty acids the solution?
Authors: Silldorff Julia , Fura Tomasz , Dudek Marcin , Zaucha Radosław , Felińska Zuzanna , Iszczuk Oliwia , Anczyk Stanisław , Gajkiewicz Magdalena , Zając Małgorzata
Published: August 2024

Introduction and objective
Omega-3 fatty acids possess numerous physiological characteristics, including anti-inflammatory, lipid-lowering, antiarrhythmic, and antithrombotic effects. There has been an ongoing discussion about their potential positive effects on human health and the extent of their influence. In this review, we will explore the current understanding of how omega-3 fatty acids impact the development of cardiovascular diseases.
 
Review methods
A review of publications on the effects of omega 3 fatty acids was conducted using the PubMed platform. The main keywords used in the search were "omega 3 fatty acids" and "cardiovascular diseases". The search included a review of the latest scientific work on the effects of omega 3 fatty acids on the body.
 
Abbreviated description of the state of knowledge
Omega-3 fatty acids exhibit diverse molecular mechanisms that are beneficial in combating cardiovascular diseases. Reducing serum triglycerides is one of the ways in which omega 3 fatty acids have an advantageous effect on the cardiovascular system. Dietary sources and supplementation offer potential benefits.
Summary
Omega-3 fatty acids, including EPA and DHA, exhibit various molecular mechanisms such as antithrombotic, anti-inflammatory, and lipid-lowering effects, which are crucial in combating CVDs. Dietary sources of omega-3 include both animal and plant products. Supplementing with omega-3 fatty acids, particularly in patients with elevated triglyceride levels, can significantly reduce CVD risk factors and mortality rates. Recommendations suggest consuming 2 servings of fish per week or supplementing with DHA + EPA to support cardiovascular health. Despite some controversies in research findings, omega-3 supplementation remains beneficial. Ongoing research continues to explore the optimal use and efficacy of omega-3 fatty acids in cardiovascular health.
Balancing Cardiovascular Health: Assessing the Impact of Physical Activity on Athletic Cardiac Adaptations and Cardiac Pathology
Authors: Hądzlik Izabela , Piotrowski Jan , Biały-Karbowniczek Julia , Słychan Katarzyna , Jędrasek Aleksandra , Bulska Klaudia , Jędrasek Tomasz , Łuczak Blanka , Pogoda Julia , Sławek Konrad
Published: August 2024

Physical activity is an effective therapy for preventing and treating cardiovascular diseases.   However, studies show a curvilinear relationship between exercise and survival, with diminishing returns beyond optimal fitness levels. Extreme athletic training can harm some individuals, as long-term training in professional athletes can lead to Athlete's Heart Syndrome (AHS), characterized by structural heart changes and altered cardiac conduction due to high-intensity exercise. Intense exertion also increases the risk of sudden cardiac death by exacerbating underlying cardiac conditions. A step-by-step multimodality approach, starting with personal and family history, clinical evaluation, and 12-lead ECG, followed by further investigations like exercise testing, echocardiography, 24-hour ECG Holter monitoring, cardiac MRI, CT, nuclear scintigraphy, or genetic testing, is essential for differentiating between extreme physiological adaptations and cardiac pathology. In this process, cardiovascular imaging is crucial for identifying structural abnormalities in athletes within the grey zone between normal adaptations and early cardiovascular disease.
The Role of Dietary Fiber in Gastrointestinal Health: Focus on Irritable Bowel Syndrome and Diverticular Disease
Authors: Kapler Marta , Kotula Jacek , Mąsior Magdalena Natalia , Zinkow Karolina , Gawlik Łukasz Marek
Published: August 2024

Dietary fiber (DF) encompasses a variety of plant-derived carbohydrates resistant to human digestive enzymes, significantly influencing gastrointestinal health.  This study examines the role of DF in managing Irritable Bowel Syndrome (IBS) and Diverticular Disease (DD), utilizing comprehensive analysis from PubMed, Google Scholar, and Embase. IBS, affecting 10-20% globally, involves complex brain-gut interactions, motility issues, and microbiota changes. Soluble fiber like psyllium reduces IBS symptoms by improving stool consistency and regulating bowel movements. However, the role of DF in DD is more nuanced. While the reports on the impact on diverticulosis prevalence are contradictory, numerous moderate-quality studies confirmed the protective effect against recurrent diverticulitis and hospitalization. The effect of different fiber types on this matter was not widely explored which might explain the discordances between the studies. Further research is essential to fully understand the diverse effects of different types of DF on gastrointestinal (GI) health. This way, exhaustive guidelines specific to each fiber type and disease phenotype could be developed, allowing to tailor the dietary recommendations to each patient, optimizing the management of symptoms of IBS and DD, and improving the quality of life.
Health Aspects of Amateur Long-Distance Running
Authors: Ruta Damian , Bocianiak Bogumił , Kajka Anna , Hamerska Julia , Antczak Joanna , Hamerska Laura , Fenrych Urszula , Wojtczak Karolina , Skupińska Olga , Lipska Julia
Published: August 2024

Introduction: Running, as a generally accessible form of physical activity, is recognized as a popular means of preventing lifestyle diseases. Each year, an increasing number of people of various ages, levels of training, and physical fitness participate in mass running events.
Purpose: The study aims to identify the opinions of amateur long-distance runners regarding health.
Material: 140 individuals from several Polish provinces, approximately 30 years old.
Method: A proprietary questionnaire survey.
Results: The most important factor motivating the respondents to engage in long-distance running is the improvement of sports performance, followed by the need to relieve stress, improve quality of life, and, to a lesser extent, health goals. According to most respondents, endurance-based long-distance running is healthy because it improves physical fitness, positively affects the cardiovascular and respiratory systems, enhances immunity, and is a way to relieve stress. Only a few respondents believe that running is not healthy. The main forms of preparation for half marathons and marathons among runners include warm-up exercises before the planned effort and strength and muscle stretching exercises. In the studied group of runners, past injuries do not diminish the satisfaction of engaging in long-distance running. Despite a significant number of respondents having experienced injuries in the past while practicing this sport, they still consider running to be healthy.
Conclusions: Long-distance running brings numerous health benefits. It improves physical fitness, positively affects cardiovascular function, including lowering blood pressure, significantly enhances sleep quality, and helps reduce stress, as confirmed by the respondent’s opinions.
Irritable bowel syndrome: systematic review of origin, pathology, diagnosis and treatment
Authors: Kwiliński Kacper , Zdunek Roksana , Strus Karolina , Madera Magdalena , Kruszewski Adrian , Dąbrowska Anna , Paduszyńska Natalia , Wawrzyńska Barbara
Published: August 2024

Irritable bowel syndrome is the most common problem of gastrointestinal practice worldwide. It contains group of symptoms that affect the gastrointestinal tract. People with IBS may experience abdominal pain, diarrhea, constipation, cramps.
  It’s still being under discussion whether the irritable bowel is a pathological or a psychological syndrome.  People report various symptoms, so they also consult doctors of different medical specializations.  For the same reason doctors may have problems with accurate diagnosis of IBS.
As evidenced by recent studies, IBS is associated with psychological distress and impaired quality of life. It’s also important from economical and medical care system point of view - they utilize the health care system to a greater degree than patients without this diagnosis.
The aim of this review is to provide a comprehensive evidence-based review of the diagnosis, pathogenesis and treatment to guide clinicians diagnosing and treating their patients.
Nanosecond laser cleaning method for high-capacity fast storage and data multiplexing in ARM architecture
Authors: Wang Chenyu , Sun Ting , Hu Zhihua
Published: August 2024

As the application of laser cleaning technology continues to expand, various fields have put forward higher requirements for the performance and quality of the operation, and at present, laser cleaning has problems such as low efficiency in handling repetitive tasks, and the system deployment and maintenance costs are high. This paper proposes a nanosecond laser cleaning method based on ARM architecture with high-capacity fast storage and data reuse, integrating high-capacity fast storage technique and data reuse strategy to optimize the laser cleaning process. In this paper, SDRAM is used to store and record the laser scanning path, Cache is integrated to weaken the data calling delay and improve the system response speed, and the scanning cycle is finely adjusted by combining positional modulation laser frequency technology to avoid the edge erosion caused by the motor deceleration and to ensure the homogeneity and accuracy of laser cleaning. The results indicate that, under the same output point conditions, the dynamic phase difference spiral algorithm in this paper outperforms the linear filling algorithm in terms of speed and data filling efficiency, reducing the burden of repetitive task calculations. While maintaining surface erosion uniformity during cleaning, excessive erosion is prevented, leading to a comprehensive enhancement in the overall efficiency and performance of laser cleaning operations.
Comparison of the composition of „eco”, „bio”, „natural” and „organic” lipsticks and lipbalms with „ordinary” lipsticks and lipbalms
Authors: Siembida Karolina , Kalicinska Jadwiga , Spiewak Radoslaw
Published: August 2024

Many cosmetic products available on the market are currently named as "ecological", "organic", "natural" or "bio". Consumers may be convinced that usage of "natural" products provides a lower risk of undesirable activities. Aim: Comparison of the composition of lipsticks and lipbalms declared by manufacturers as "natural", "ecological", "biological" and "organic" with lipsticks and lipbalms with no such declaration. Materials and methods:100 drugstore products were analyzed: 50 declared as "natural", "ecological", "biological" or "organic" and 50 "ordinary" products without such declaration. Photographic documentation of labels of cosmetics was collected. Based on documentation tabels of cosmetics ingredients were prepared. Using CosIng base components were assigned to their functions and the frequency of their occurrence in particular groups was analyzed. Frequency differences of occurrence of individual substances were analyzed using Chi2 test. Presence of ingredients that may cause health problems based on European Parliament and Council regulation about cosmetics products (no. 1223/2009, 20th of November 2009) was analyzed. Results: 100 analyzed products had total of 402 individual substances; 321 of wich were included in "ordinary" lipsticks and lipbalms, 204 were included in "natural" products. 6 problematic preservatives were found in 4 (8%) of natural and 23 (46%) of ordinary products (p < 0,001). Phenoxyethanol was the most popular preservative wich presented statistically significant difference and was found in 8 (16%) ordinary products. Fragrance were presented 46 times in 18 (36%) of natural products and 66 times in 20 (40%) of ordinary products (p = 0,680). The most popular fragrance was castor oil, found in 32 (64%) of natural and 21 (42%) of ordinary products (p = 0,028). Parfum were found in 13 (26%) of natural and 22 (44%) of ordinary products (p = 0,059). UV filters were found in 6 (12%) of natural and 32 (64%) of ordinary products (p = 0,001), statistically significant difference was presented. The most popular UV filter was ethylhexyl methoxycinnamate, found in 3 (6%) of natural and 9 (18%) of ordinary products (p = 0,124). 14 dyes were identify in 23 (46%) of natural and 20 (40%) of ordinary products (p = 0,161). Conclusions: Quantity of UV filters and preservatives found in natural (certified as "eco", "bio", "natural", "organic") products is smaller than quantity found in ordinary (non certified) products. Natural products ususally contain less of potentially sensitizing substances wich makes them seem to be safer to use. Presense of certificates such as "eco", "bio", "natural" and "organic" placed on the packages does not guarantee safety.
Uso da abordagem multicritério na priorização da carteira de pedidos de uma indústria metalúrgica
Authors: Pereira Junior Marco Antonio Moraes , Ramos Maria Clara Guedes , Hernandez Cecilia Toledo , Rangel Luis Alberto Duncan , Neves Tiago Araujo
Published: August 2024

O tema de priorização de clientes é uma atividade complexa e de alta capacidade analítica, considerando o mercado competitivo da atualidade. Para uma tomada de decisão eficaz, o processo deve considerar o máximo de variáveis, com parâmetros quantitativos e qualitativos. Este artigo tem como objetivo determinar quais clientes devem ser priorizados em uma carteira de pedidos de uma indústria metalúrgica através do Software SuperDecision, utilizando a abordagem multicritério AHP com Ratings. Primeiramente, foi realizado uma pesquisa bibliográfica a respeito da Análise Multicritério, com foco no método e no software escolhido, a fim de conhecer os conceitos e as aplicações destas metodologias, que possuem como foco a priorização de um conjunto de pedidos de clientes com variáveis que sejam importantes para o mercado metalúrgico. Posteriormente, foram quantificados os pedidos, de acordo com quatro critérios escolhidos pelos especialistas, demonstrando que os pedidos dos clientes C3, C1 e C2 deverão ser priorizados. Aumento da satisfação dos clientes, de capacidade e eficiência de produção também foram detectados.
Influência das práticas comportamentais e técnicas no desempenho e riscos de sustentabilidade
Authors: Romano Andre Luiz , Ferreira Luis Miguel D. F. , Caeiro Sandra Sofia F. S.
Published: August 2024

A crescente importância da sustentabilidade nas cadeias de suprimento é elemento central dessa pesquisa, aliada ao aumento da complexidade das cadeias por aspectos geográficos, políticos e comportamentais. O objetivo dessa pesquisa foi examinar o papel das práticas comportamentais e técnicas e a importância delas para o desempenho organizacional e nos riscos de sustentabilidade. Nessa pesquisa, com 152 empresas, foi realizada uma modelagem de equações estruturais (SEM) identificando o teste das hipóteses do modelo estrutural. As principais descobertas da pesquisa são consistentes com o modelo de hipótese e destacam uma influência positiva das práticas comportamentais nas práticas técnicas e no desempenho em sustentabilidade nas empresas. Este estudo contribui para os gestores, oferecendo uma visão da gestão dos riscos de sustentabilidade na cadeia de suprimentos. O estudo contribui ainda para a literatura, apresentando o conhecimento sobre a relação entre os riscos, desempenho e as práticas de sustentabilidade.