bluuebunny/crossref_metadata_2025 huggingface dataset:
Determinación de contaminantes orgánicos persistentes en leche de vaca de producción nacional por medio de la técnica de cromatografía de gases acoplada a espectrometría de masas (GC/MS)
Authors: Marranzini Camila , Bello Lizaira , Vallejo Degaudenzi Alejandro , Gómez Aris Mendis , Echavarría Enmanuel
Published: January 2021

Los contaminantes orgánicos persistentes (COP) son sustancias químicas orgánicas capaces de persistir en el ambiente, transportase a larga distancia, bioacumularse y biomagnificarse en los ecosistemas. Los efectos nocivos de estos compuestos sobre el medio ambiente y la salud de los seres vivos son preocupantes. En particular, los seres humanos pueden entrar en contacto con los COP al consumir alimentos contaminados de origen animal con un alto contenido en grasa. En la República Dominicana estos compuestos se han utilizado y generado ampliamente. Sin embargo, se desconoce cuáles son los niveles de exposición de COP a los que está expuesta la población. Por tanto, este estudio tuvo como objetivo determinar la presencia de 34 COP en cinco principales marcas de leche de vaca de producción nacional. La preparación de las muestras se realizó mediante el método de extracción QuEChERS y la técnica analítica utilizada fue la GC/MS. Los resultados obtenidos indicaron que no hay presencia de los COP evaluados en ninguna de las muestras de leche de vaca, lo cual sugiere que su consumo no representa una amenaza para la salud de los consumidores. Además, este estudio aporta al conocimiento sobre la evaluación de los COP en la República Dominicana.
Ikhlas Kontraktual dan Ikhlas Non Kontraktual: Kontekstualisasi Motto Ikhlas Beramal di Era Human Capital 9
Authors: Hafit Syaifullah Dian , Yusuf Budi Permana , Sunarta
Published: January 2021

Ikhlas beramal merupakan motto Kementerian Agama yang belum pernah didefinisikan secara institusional oleh Kementerian Agama sejak awal kelahirannya. Artikel ini bertujuan untuk mengidentifikasi nilai-nilai organizational citizenship behavior dan employee engagement mana saja yang yang bersesuaian dengan makna ikhlas beramal. Artikel ini menggunakan pendekatan kualitatif dengan teknik literature study, pengumpulan data dilakukan melalui Teknik stock taking dengan cara mengumpulkan dan mengklasifikasi berbagai textbook dan jurnal serta berbagai penelitian terdahulu yang relevan. Kajian ini menemukan bahwa organizational citizenship behavior dapat dipadankan dengan ikhlas non kontraktual dan employee engagement dapat dipadankan dengan ikhlas kontraktual karena memiliki nilai-nilai tertentu yang bersesuaian dengan beberapa nilai keikhlasan. Diperlukan berbagai kajian lanjutan untuk menguji temuan ini.
Pengaruh Individual Motivation Dan Organization Climate Terhadap Kinerja Pegawai Sekretariat Direktorat Jenderal Pencegahan Dan Pengendalian Penyakit Kementerian Kesehatan RI
Authors: Rizka Apriasdittika  , Hartono Bambang Dwi
Published: January 2021

Penelitian ini bertujuan untuk mengetahui pengaruh individual motivation dan organizational climate terhadap kinerja pegawai Sekretariat Direktorat Jenderal Pencegahan dan Penegendalian Penyakit Kementerian Kesehatan RI. Hipotesis yang di uji adalah : (1) Terdapat pengaruh langsung individual motivation terhadap kinerja pegawai, (2) Terdapat pengaruh langsung organizational climate terhadap kinerja pegawai, (3) Terdapat pengaruh langsung individual motivation terhadap organizational climate, (4) Terdapat pengaruh langsung individual motivation terhadap kinerja pegawai melalui organizational climate. Metode yang digunakan kuantitatif dengan teknik analisis jalur (Path Analysis). Pengambilan sampel menggunakan teknik acak sederhana proporsional (proportional random sampling). Sampel yang digunakan pegawai Aparatur Sipil Negara di Kantor Sekretariat Direktorat Jenderal Pencegahan dan Penegendalian Penyakit Kementerian Kesehatan RI yaitu sebanyak 111 responden. Data diperoleh dengan menggunakan kuesioner yang berbentuk skala likert. Hasil penelitian menunjukkan bahwa: Pertama, skor koefisien jalur antara individual motivation terhadap kinerja pegawai (ρ31) sebesar 0,338 dengan thitung sebesar 3,653 >  ttabel (1,981 pada α = 0,05). Karena thitung 3,653 >  ttabel 1,981 pada α = 0,05, maka H0 di tolak, hasil penelitian membuktikan bahwa individual motivation berpengaruh langsung dan positif terhadap kinerja pegawai.. Kedua, skor koefisien jalur antara organizatioanl climate terhadap kinerja pegawai (ρ32) sebesar 0,362 dengan thitung sebesar 3,905 >  ttabel  (1,981 pada α = 0,05). Karena thitung 3,905 >  ttabel 1,981 pada α = 0,05, maka H0 di tolak, hasil penelitian membuktikan bahwa organizatioanl climate berpengaruh langsung dan positif terhadap kinerja pegawai. Ketiga, skor koefisien jalur antara individual motivation terhadap organizational climate (ρ21) sebesar 0,583 dengan thitung sebesar 7,492 >  ttabel (1,981 pada α = 0,05). Karena thitung 7,492 >  ttabel 1,981 pada α = 0,05, maka H0 di tolak, hasil penelitian membuktikan bahwa individual motivation berpengaruh langsung dan positif terhadap organizational climate. Keempat, skor koefisien jalur pengaruh individual motivation terhadap kinerja pegawai melalui organizational climate sebesar 0,549 berarti hasil penelitian membuktikan bahwa terdapat pengaruh individual motivation terhadap kinerja pegawai melalui organizational climate.
“Twisting the glory of both halves of this time...”: on the spatio-temporal and mythological manifestation in “The Lay of Igor’s Host”
Authors: Porol Olga A.
Published: January 2021

The article puts forward a hypothesis about the existence of the goddess of the ancient Slavs Slava in the Lay of Igors Host. Some dark places have been translated. When analyzing the work, a search for text parallels was used. Revealed and substantiated the relationship between separate Old Russian and Church Slavonic vocabulary. The semantic shades of the words mind, heart, time, path, contained in dark places are considered. An attempt was made to understand the peculiarities of the manifestation of space-time forms in the Lay of Igors Host. The coexistence of the present and the past tense in The Lay of Igors Campaign is explained by the timeless forms of being, the recognition by the ancient Russian scribe of two spaces. The duality in The Lay of Igors Host is manifested in the use of ancient pagan images, old words and epics of this time. The Church Slavonic word, dating back to the text of the Bible, contains many semantic shades, the explanation of which can reveal the depth and richness of the Old Russian text. The expressions that go back to the theme of Christianity are analyzed. At the end of the work, the emerging joyful attitude of the author of The Lay of Igors Host to the hero who destroyed his army and escaped from captivity is regarded as Christian. Willfulness and the fulfillment of Gods will are present in the character of Prince Igor, in his actions. Christian images in The Lay of Igors Host and the authors kind attitude to the defeated prince tell the reader about the new established Christian world, which, however, is in a difficult relationship with the world of former words, ancient pagan Slavic images.
Formation of international broadcasting in Russia and abroad: historical-genetic and comparative analysis
Authors: Yefanov Aleksandr A. , Efendieva Nailya E.
Published: January 2021

The article provides a historical-genetic and comparative analysis of foreign broadcasting. In the chronotopic aspect the advanced experience of foreign countries (Germany, England, France, USA) is compared with the peculiarities of the formation of foreign broadcasting in Russia. The main stages of the development of foreign broadcasting are highlighted. The dominant media communication channels through which foreign broadcasting activities are carried out are determined. Based on the results of the study, the conclusion is made that at the first stage of its development, foreign broadcasting was not an instrument of foreign policy and rather contributed to the cultural enrichment and support of its compatriots in other countries. However, wartime predetermined the future tonality of foreign broadcasting - a propaganda focus. During the Second World War, foreign broadcasting was used in many countries to discredit the enemy, as well as to motivate the military and the population in the rear. During the Cold War, foreign broadcasting strengthened its propaganda purpose, continuing to implement in its discourse defamatory strategies against competitors and adversaries, against the background of which a new concept of information war was formed. In general, foreign broadcasting as a discourse strategy is mainly used in the course of geopolitical conflicts, both open and latent. In the process of evolution of media communications, an intensification of the struggle for influence on the external audience was observed, which was most clearly manifested as a result of the implementation of foreign broadcasting in the field of television, based on the audiovisual capabilities of this type of media. In the 21st century, the information struggle for the interpretation of reality and, as a consequence, the construction of public opinion on a global scale began to take place in the field of the Internet, where foreign broadcasting has acquired a global character.
The genesis of Russian electoral PR: issue of periodization
Authors: Shilina Marina G. , Mintusov Igor E.
Published: January 2021

In modern Russia, the electoral PR practices make up a significant share in the national public relations structure but have not been systematically studied until now. The directions of communication activities, the object-subject area, as well as the problems of genesis, which is the basis of research in each subject area, have not been systematically studied yet. The research problem is determined by the lack of sufficient novelty and specificity of empirical material, the lack of significant theoretical and methodological foundations and concepts. For the first time in the Russian scientific discourse, the paper presents the definition of electoral PR as a communication process and determines the features of its genesis from the late 1980s to 2014 in the Russian public relations formation context. On the basis of the structural-functional and model approaches, the characteristics, structure, models, messages, functions, and parameters of electoral PR institutionalization are fixed. For the first time, the paper presents the elements, the new subjects of the electoral PR communication models in the Russian Federation. The proposed author's PR periodization methodology is relevant for the electoral public relations periodization as well. The legal regulation of the electoral process as one of the basic conditions for the transformation and periodization of electoral PR is mentioned. The revealed characteristics of the genesis of Russian electoral PR make it possible to record the incompleteness of the process of its institutionalization by the mid-2010s. The presented methodological grounds for studying elective public relations seem to be basic for further research in this area.
Analysis of the effects of caffeine and dioxidine on biochemical indicators of blood in mouse
Authors: Durnova N. A. , Sheremetyeva A. S. , Karetnikova A. Yu.
Published: January 2021

Relevance . In connection with the widespread use of caffeine, an important issue is the study of its interaction with substances that can exhibit toxic effects. Objective. The aim of the study is to assess the degree of influence of caffeine and dioxidine on the biochemical parameters of blood in mice in the forced swimming test. Materials and methods. The studies were carried out on 6 groups of male mice: control and five experimental. During 15 days of the experiment, the animals of the control group were injected with physiological saline, and the experimental animals were injected with caffeine at a dose of 40 mg/kg or 100 mg/kg (1 and 2), dioxidine in an amount of 200 mg/kg (3), and caffeine was combined and dioxidine (4 and 5). Biochemical parameters were used to determine the content of glucose, cholesterol, urea, creatinine, the activity of aspartic and alanine aminotransferases. Results . The introduction of caffeine at a dose of 40 mg/kg led to a decrease in glucose levels below normal and an increase in cholesterol and urea concentrations. The use of caffeine at a dose of 100 mg/ kg caused a decrease in glucose levels below normal and an increase in urea concentration. With the introduction of dioxidine at a dose of 200 mg/kg, an increase in the level of glucose, cholesterol, urea, as well as the activity of AST and ALT was taken. The combined use of caffeine and dioxidine by the 15th day led to 100 % mortality in experimental animals. Conclusions . The results of the experiment indicate that the introduction of caffeine at a dose of 40 mg/kg and 100 mg/kg leads to an increase in most of the measured parameters relative to the control values, but they do not go beyond normal values, however, a decrease in glucose levels is noted. These changes in indicators are due to the predominance of catabolic processes over anabolic ones. In animals treated with dioxidine, a significant increase in the concentration of metabolites and the activity of blood enzymes was found, especially an increase in AST and ALT was noted, which indicates a predominant lesion of cardiomyocytes. The mortality rate of the experimental groups receiving caffeine and dioxidine together by the last day of the experiment is due to the action of an excessive stress factor leading to the depletion of the adaptive capabilities of the organism and the death of experimental animals.
A natureza em “Os Brilhantes’, Romance de Rodolfo Teófilo
Authors: Figueira Felipe Gonçalves
Published: January 2021

Rodolfo Teófilo foi farmacêutico, político e romancista. Sua produção intelectual compreende desde cursos de botânica e tratados de farmácia a contos e romances. No presente artigo, é evidenciada a importância do discurso cientificista do final do século XIX para a representação da natureza brasileira no romance Os Brilhantes (1906), publicado originalmente em 1895.
FAKE NEWS: UM EXAME SEMIOLINGUÍSTICO DA DESINFORMAÇÃO EM AMBIENTES SÓCIO-INTERATIVOS DIGITAIS
Authors: Monteiro Alexandre Henrique dos Santos , REBELLO ILANA DA SILVA
Published: January 2021

O presente trabalho tem o objetivo de examinar, sob a luz da Teoria Semiolinguística de Patrick Charaudeau, em uma postagem de facebook, as intencionalidades psico-sócio-discursivas que determinam as orientações discursivas expressas pelas visadas, bem como os procedimentos de construção enunciativa de ordem linguística que explicitam os diferentes tipos de relações do ato enunciativo.
Fake News e Democracia: Contribuições da Semiótica Discursiva acerca da Verdade e da Informação na Internet
Authors: Kalil Filho Marcos da Veiga
Published: January 2021

As fake news consistem em procedimento de propagação de conteúdos falsos em que o apagamento ou a dissimulação da autoria representa estratégia comum para a eficácia da comunicação. O reconhecimento de seu impacto nos meandros democráticos exige das teorias do discurso um esforço de compreensão do fenômeno. O presente trabalho discute a problemática a partir do arcabouço teórico-metodológico da semiótica discursiva.
A MANIPULAÇÃO INFORMATIVA E SEU MODUS OPERANDI NO ENQUADRAMENTO IDEOLÓGICO NAS REDES SOCIAIS
Authors: Duque Paulo Henrique , Da Silva Eduardo Alves
Published: January 2021

O presente estudo lança luz na questão do processo manipulativo de informações veiculadas nas redes sociais através do processo de framing e reframing. A partir de uma abordagem qualitativa, o artigo apresenta o modo como o fluxo de informações veiculadas por fake news nas redes sociais se efetiva no sentido da construção, desconstrução e reconstrução de frames.
FAKE NEWS: DISCREPÂNCIA DE SENTIDOS E EFEITOS SOBRE AS RESISTÊNCIAS
Authors: Grigoletto Evandra , Silva Sobrinho Helson Flávio da
Published: January 2021

Fundamentado na Análise do Discurso pecheuxtiana, este artigo analisa, pelo viés da resistência, as discrepâncias de sentidos presentes em fake news que circularam durante a campanha eleitoral de 2018. Marcadas por equívocos e contradições, as fake news, inscritas no universo dos discursos não estabilizados logicamente, funcionam no sentido de criar obstáculos, frear as resistências do sujeito ao poder dominante.
A morte em morte e vida severina: estudo sobre a dimensão trágica do texto de João Cabral de Melo Neto
Authors: Figueira Felipe Gonçalves
Published: January 2021

O presente estudo busca relacionar a ideia da morte severina com a experiência da tragédia grega. A análise comparada evidencia as dimensões trágicas desse texto de João Cabral de Melo Neto. Para tanto, são importantes as proposições metodológicas fundadas no pensamento dialógico de Mikhail Bakhtin (2008; 2015). Relevantes, também, os estudos de Vernant e Vidal-Naquet (2008) sobre a Tragédia.
Os elos entre memória e teatro: a recepção da performance e o grupo giz-en-scène
Authors: Rodrigues Marco Aurélio
Published: January 2021

O presente trabalho aborda três elementos da teoria da Recepção da Performance (HALL, 2010), mimese, memória e psique, para discutir algumas evidências nas apresentações do grupo teatral Giz-en-Scène e a importância que os processos mnemônicos têm, há séculos, enquanto partes constitutivas da arte dramática.
Você me dá a sua palavra?: um livro infinito
Authors: Bosi Isabela
Published: January 2021

Neste artigo, buscamos criar um diálogo com a obra Você me dá a sua palavra?, da artista visual Elida Tessler, e refletir acerca da literatura para além de suas formas tradicionais. Nessa obra, Tessler pede a palavra do outro, solicitando que seja grafada em prendedores de roupa. De 2004 até agora, já somam mais de seis mil palavras, em diferentes línguas. Com esse gesto, a artista desloca a palavra e o objeto de seus usos habituais, compondo um livro infinito, sempre por vir, em consonância com o pensamento de Maurice Blanchot. Ao longo do artigo, convocamos para o diálogo outros pensadores e artistas, como Virginia Woolf, Joan Brossa, Jean-Luc Nancy e Jorge Luis Borges.
Algumas vozes do mundo: na poesia portuguesa pós-1961
Authors: Braz Paulo
Published: January 2021

O ensaio busca descrever um percurso crítico em torno de alguns nomes destacados da poesia portuguesa pós-1961, tendo como mote principal a discussão em torno da condição mundana em que ela se implica, ao que se pode inferir a influência de certas correntes da modernidade baudelairiana a partir da imagem da queda e da profanação.
Poeta das "Minas"e do luar: Alphonsus de Guimaraens na poesia de Carlos Drummond de Andrade e de Murilo Mendes
Authors: Oliveira Ilca Vieira de , De Almeida Rocha Wesley Thales
Published: January 2021

O poeta simbolista Alphonsus de Guimaraens foi diversas vezes celebrado pelos escritores modernistas, como Mário de Andrade e Manuel Bandeira, como representante do patrimônio cultural brasileiro, conforme também o eram, para eles, a arte e a arquitetura das cidades históricas mineiras. Carlos Drummond de Andrade e Murilo Mendes, dois dos mais importantes modernistas de Minas, estenderam essa celebração em seus versos, associando a imagem e a obra do poeta oitocentista ao universo simbólico de Minas. Do alto da modernidade, em afirmação na cultura e na literatura brasileiras, Drummond e Murilo voltam o olhar para o poeta do passado, à sua figura oclusa entre as ‘minas” de Ouro Preto e Mariana e à sua poesia melódica e quimérica, e as reinserem no contexto pouco contemplativo do século XX.  Este trabalho objetiva elaborar uma leitura crítica dos poemas: ‘Luar para Alphonsus”, de Versiprosa, ‘A visita”, de A paixão medida, e ‘Em memória de Alphonsus de Guimaraens”, Amar se aprende amando, de Carlos Drummond, e do poema ‘Contemplação de Alphonsus”, de Contemplação de Ouro Preto, de Murilo Mendes, observando como a imagem do poeta simbolista se faz presente nos versos desses poetas mineiros do século XX e como ela insere novos signos e sentidos à poética dos dois autores e à existência no mundo moderno.
OS TRIÂNGULOS COMPETITIVO-COOPERATIVOS NAS RELAÇÕES INTERNACIONAIS: UMA CONTRIBUIÇÃO TEÓRICA DO PODER A PARTIR DO ESTUDO DE CASO DAS FORÇAS POLÍTICAS INTERNAS E EXTERNAS NA AMÉRICA DO SUL
Authors: Rodrigues Bernardo Salgado
Published: January 2021

In the 21st century, power projects in South America constitute disputes that comprise a dialectical correlation between Internal and External Political Forces. In this sense, this article aims to conduct an innovative debate based on the theoretical formulation called Competitive-Cooperative Triangles of Power, taking the South American region as a case study. From a realist view of international relations and by using an empirical-deductive methodology, the objective is to achieve an epistemological construction regarding power in the international system, explaining the challenges and possibilities of the South American Internal Political Forces.
“BELT AND ROAD INITIATIVE”: CHALLENGES AND OPPORTUNITIES FOR CHINA AND FOR THE WORLD
Authors: De Conti Bruno , Mozias Petr
Published: January 2021

The “Belt and Road Initiative” (BRI) is quite impressive in the amount of resources and the number of countries involved, but also in the diversity of intentions it reveals. In one hand, it is a demonstration of strength for China in the international arena; in the other hand, it is an effort of the Chinese government to face important economic problems. Nevertheless, it may not be studied only from the point of view of China, since it has direct and indirect impacts over the whole globe. This paper aims therefore to analyze BRI under the framework of associated opportunities and challenges for China and for the rest of the world.
MULTIDISCIPLINARY MANAGEMENT OF A RARE CASE OF MIXED TOTAL ANOMALOUS PULMONARY VENOUS CONNECTION
Authors: Ghidini Filippo , Castaldi Biagio , Padalino Massimo , Dall'Igna Patrizia
Published: January 2021

A rare case of mixed total anomalous pulmonary venous connection (TAPVC)
associated to right extra-lobar bronchopulmonary sequestration (BPS) was
diagnosed at birth in a full-term newborn. At one month of age, the
patient underwent embolization of the BPS, complicated by coil
entrapment in the right common iliac artery requiring urgent laparotomy.
Few days later, the congenital cardiac repair was accomplished
uneventfully. At 12-months follow-up, the patient did not have pulmonary
hypertension, but presented a moderate stenosis of the right femoral
artery, which was effectively treated with anticoagulation therapy.
Impact of catheter contact angle on lesion formation and durability of pulmonary vein isolation
Authors: Ohta Masayuki , Hayashi Kentaro , Sato Hiroyuki , Noto Takahiro , Kawahatsu Kandoh , Katagiri Masaya , Mita Tomohiro , Kazuno Yoshio , Sasaki Shunsuke , Doi Takahiro , Hirokami Mitsugu , Tanaka Shigemichi , Yuda Satoshi
Published: January 2021

Introduction Little is known on the effect of catheter contact angle on
lesion formation and durability of pulmonary vein isolation (PVI).
Methods Both in vitro experiment and retrospective observational study
were conducted. For in vitro experiment, radiofrequency lesions were
created on explanted swine hearts in three different catheter contact
angles (0°, 45°, and 90°). In the retrospective observational study, we
assessed patients who had undergone repeat catheter ablation due to
atrial fibrillation recurrence after initial PVI. When pulmonary vein
(PV) reconnection was observed, we analyzed the previous ablation points
within and without the gap area. The gap areas were defined where
ablation had changed the PV activation sequence or eliminated the PV
potential in the repeat session. Results In the in vitro experiment,
lesion width was the smallest (5.3 ± 0.4 mm) in perpendicular contact
compared to 0° (vs 5.8 ± 0.5 mm, p=0.040) and 45° (vs 6.4 ± 0.4 mm,
p<0.001). In the retrospective observational study, we
assessed 666 tags of 16 patients with PV reconnections, and 60 tags were
in the gap area. Tags in the gap area had longer interlesion distance
(odds ratio [OR] 1.49, p < 0.001), greater contact force
variability (OR 1.03, p = 0.008), and higher rate of perpendicular
contact (OR 3.26, p < 0.001) on multivariate analysis.
Conclusion Perpendicular contact was associated with a smaller lesion
and higher rate of PV reconnection.
Assessing prey selection of snow leopard in Mt. Kangchenjunga, Nepal
Authors: Thapa Kamal , Schamitt Natalie , Pradhan Narendra , Acharya Hem , Rayamajhi Santosh
Published: January 2021

In spring of 2012, we studied the feeding habits of snow leopard using a
comprehensive approach that combines fecal genetic sampling, macro and
microscopic analysis of snow leopard diets and direct observation of
Naur and livestock in Kangchenjunga Conservation Area of east Nepal. Out
of collected 88 putative snow leopard scat samples from 140 transects
(290 km) in 27 (4*4 km2) sampling grid cells, 83% were confirmed to be
from snow leopard. The genetic analysis accounted for 19 individual snow
leopards (10 male and 9 female) with a mean population size estimate of
24 (95% CI: 19- 29), and an average density of 3.9 snow leopards/100
km2 within 609 km2. Total available prey biomass of Naur and Yak was
estimated at 355,236 kg (505 kg yak/km2 and 78 kg Naur/km2). From the
available prey biomass, we estimated snow leopards consumed 7% annually
which was comprised of wild prey (49%), domestic livestock (45%), and
6% unidentified items. The estimated 47,736 kg Naur biomass gives a
snow leopard-Naur ratio of 1: 59 on a weight basis. The proportion of
young Naur was estimated at 17%, with an almost double predation rate
at 28%. Predators such as common leopard and wolf share the same
habitat and might compete with snow leopard for prey which will likely
influence future predator-prey associations in KCA. Along with livestock
insurance scheme improvement, there needs to be a focus on improved
livestock guarding as well as engaging and educating local people to be
citizen scientists on the importance of snow leopard conservation,
involving them in long-term monitoring programs and promotion of
ecotourism.
Persistently Elevated Urine β2-MG and Decreased BMD in a Patient with ADV-induced Hypophosphatemic Osteomalacia and Fanconi’s Syndrome After Drug Withdrawal
Authors: Zhang Yu , Long Jianfei , Tong Shuangmei , Bin Wang
Published: January 2021

This is the first case of adefovir dipivoxil (ADV)-induced
hypophosphatemic osteomalacia (HO) and Fanconi’s syndrome in which bone
mineral density (BMD) is continuously reduced after drug
discontinuation. Sustained elevation of urine β2-MG also supports the
recent view that ADV-induced renal injury is not completely reversible.
Successful pembrolizumab treatment of microsatellite instability-high intrahepatic cholangiocarcinoma: A case report
Authors: IKEDA YUKI , Ono Michihiro , Omori Ginji , Ameda Saki , Yamada Michiko , Abe Tomoyuki , Fujii Shigeyuki , Fujita Miri , Maeda Masahiro
Published: January 2021

Pembrolizumab is considered to be an effective therapy for patients with
microsatellite instability (MSI)-high cancer. Here, we report a case of
MSI-high cholangiocarcinoma effectively treated with pembrolizumab. MSI
status should be actively evaluated in patients with cholangiocarcinoma.
Salvage of a mangled limb with Matriderm® augmented split-skin grafting and maggot biodebridement
Authors: Lempert Maximilian , Pape Hans-Christoph , Jukema Gerrolt
Published: January 2021

We present a case of a young woman with a mangled leg, that could be
salvaged with a combination of negative pressure wound therapy,
Matriderm® augmented split-skin grafting, and maggot biodebridement. The
aim of this case report is to outline alternative treatment options in
severe soft tissue injuries.
Peptide fragments of bradykinin show unexpected biological activity not mediated by B1 or B2 receptors
Authors: Souza-Silva Igor , Paula Cristiane de , Bolais-Ramos Lucas , Santos Anderson , Silva Filipe da , Oliveira Vívian de , Rocha Isabella da , Antunes Maísa , Cordeiro Lídia , Teixeira Vanessa , Júnior Sérgio Ricardo Scalzo , Amaral Flavio , Resende Jarbas , Fontes Marco Antônio , Menezes Gustavo , Guatimosim Silvia , Santos Robson , Verano-Braga Thiago
Published: January 2021

Background and purpose: Bradykinin [BK-(1-9)] is an
endogenous nonapeptide involved in multiple physiological and
pathological processes. A long-held belief is that peptide fragments of
BK-(1-9) are biologically inactive. Here, we have tested the biological
activities of BK-(1-9) and two major peptide fragments in human and
animal systems. Experimental Approach: Levels of BK peptides in
male Wistar rat plasma were quantified by mass spectrometric methods.
Nitric oxide was quantified in human, mouse and rat cells, and loaded
with DAF-FM. We used aortic rings from adult male Wistar rats to test
vascular reactivity. Changes in blood pressure and heart rate were
measured in conscious adult male Wistar rats. Key results:
Plasma levels of BK-(1-7) and BK-(1-5) in rats were increased following
infusion of BK-(1-9). All tested peptides induced NO production in all
cell types tested. However, unlike BK-(1-9), NO production elicited by
BK-(1-7) or BK-(1-5) was not inhibited by B or
B receptor antagonists. BK-(1-7) or BK-(1-5) also
induced concentration-dependent vasorelaxation of aortic rings, without
involving B or B receptors. In vivo,
either intravenous or intra-arterial administration of BK-(1-7) or
BK-(1-5) induced similar hypotension response. Conclusions and
implications: BK-(1-7) and BK-(1-5) are endogenous peptides present in
plasma. They are formed, at least partially, through the BK-(1-9)
proteolysis. BK-related peptide fragments show biological activity, not
mediated by B or B receptors. These
BK-fragments could constitute new, active components of the
kallikrein-kinin system.
TOWARDS A BETTER COMPREHENSION OF ACUTE MESENTERIC ISCHEMIA AFTER CARDIAC SURGERY. AN ANALYSIS OF 33 PATIENTS.
Authors: Borioni Raoul , bellisario alessandro , Weltert Luca , Turani Franco , Garofalo Mariano , D'aleo Salvatore , Paulis Ruggero De
Published: January 2021

Background. Acute mesenteric ischemia (AMI) after cardiac surgery is a
rare but serious complication associated to high mortality. The time of
onset is the key point to correctly evaluate the clinical scenarios.
Methods. Data from adult patients who underwent laparotomy for AMI after
elective or urgent cardiac surgery were reviewed (January 2005 -
December 2019) to report their anatomoclinical features in relationship
to time of onset. Early events (within 48 hours) were allocated to Group
1, whereas late onsets were allocated to Group 2. Results. The incidence
of risk factors for non occlusive mesenteric ischemia was higher in
Group 1 (chronic renal failure 80% vs 38.8%, P <0.05, use of
inotropes 60% vs 5.5%, P <0.01, early oligo-anuria requiring
CRRT 80% vs 16.6%, P <0.01, prolonged ventilation 46.6% vs
5.5%, P <0.05), where a significative occurrence of
postoperative de novo atrial fibrillation was noted in Group 2 (55% vs
5.5%, P <0.01). The number of patients who required bowel
resection was proportionally higher in the Group 2 Conclusions. Two well
distincted categories of AMI after cardiac surgery can be classified.
The first consists of patients with well-known risk factors developing
ischemia as a result of severe visceral hypoperfusion The second
consists of patients with low comorbidity who experience late AMI as a
consequence of“trigger events”, mainly de novo atrial fibrillation.
This classification may be useful to better alert the medical staff to
the possibility of bowel ischemia at any time after cardiac surgery,
promoting early diagnosis and treatment.
Mimosa L. (Fabaceae) em Cachoeira dos Índios, Paraíba, Brasil
Authors: De Sousa Emanuel Evaristo , De Queiroz Rubens Teixeira , Pereira Maria Do Socorro
Published: January 2021

Mimosa é um gênero Neotropical, com grande representatividade na Caatinga, domínio onde está inserido o município de Cachoeira dos Índios. Na área de estudo, os representantes do gênero foram coletados no período de dezembro/2018 a janeiro/2020. Foram levantadas nove espécies de Mimosa: (M. arenosa (Willd.) Poir., M. camporum Benth., M. candollei R. Grether, M. debilis Humb. & Bonpl. ex Willd., M. invisa Mart. ex Colla, M. paraibana Barneby, M. sensitiva L., M. tenuiflora (Willd.) Poir. e M. ursina Mart.), destas, M. camporum, M. invisa e M. ursina são novos registros para o estado e M. paraibana, um táxon endêmico do Nordeste brasileiro. Sendo assim, evidencia-se a relevância deste ambiente, pois além de ampliar a distribuição geográfica do gênero na Paraíba, traz contribuições taxonômicas do grupo para flora da região.
The impact of a pulsed electromagnetic field on the seed protein content of soybean
Authors: Djukic Vojin , Miladinov Zlatica , Dozet Gordana , Cvijanovic Gorica , Miladinovic Jegor , Randjelovic Predrag , Kandelinskaja Olga
Published: January 2021

Many studies show that in the last 20 years, the increase in production per
hectare has been achieved mainly due to the creation of new varieties and
the development of plant breeding. Innovations in plant breeding are the
main way to find new traits, values and tolerances, which are the only ones
that can respond to the increased demand for yield and more efficient
production. In addition to high and stable yields, it is very important that
the soybean seed has a satisfactory technological quality. Therefore, the
aim of this study was to examine how the application of pulsed
electromagnetic fields (PEMFs) affected the protein yield of soybean seed
depending on the year, exposure time and frequency. The field trials were
conducted in the experimental field of the Institute of Field and Vegetable
Crops in Novi Sad, Serbia in 2010-2013. For this research, the seeds of a
medium-sized variety Valjevka exposed to a pulsed electromagnetic field
(PEMF) using a pulse generator and a strip applicator were used. A low
frequency pulsed electromagnetic field (16, 24, 30, 72 Hz) was used at the
exposure times of 0, 30, 60, and 90 minutes. The results of the research
show that the application of this method can increase the yield of protein
in soybean seed for more than 20%, which is a significant increase,
especially in organic production, where the use of seed treatment agents is
very restricted. However, this measure can also have an inhibitory effect if
an adverse combination of exposure time and frequency strength is selected.
Basics of navigation implant prosthetics planning
Authors: Milicic-Lazic Minja , Prokic-Maric Aleksandra , Todorovic Ana , Lazic Vojkan
Published: January 2021

Due to the development of digital technologies, the modern concept of
prosthetic-guided implantology is based on non-invasive surgical and
restorative techniques. Computer-aided planning, computer-guided workup and
computerguided surgery have largely ensured the predictability of the
therapeutic outcome. This is supported by research data related to the
frequency of implant therapy, according to which in the first half of 2020
there was an increase of 9.7%. However, anatomical limitations remain a
challenge for the implant team. The most common problem related to implant
therapy in edentulous patients is limited edentulous space in one or more
spatial planes. Improving the design of surgical guides facilitates
implantation in spatially limited and complex cases. By introducing
interactive computed tomography into the field of implantology, a
three-dimensional approach to every aspect of planning and implantation has
become possible.
Curriculum Evaluation of Light Vehicle Engineering Department with Discrepancy Model as Per Industry Needs
Authors: Aprianto Anggi , Rizal Fahmi , Lapisa Remon , . Ambiyar , Wakhid Wakhinuddin , . Sukardi , Riyanda Afif Rahman
Published: January 2021

The implementation of the curriculum as per industrial needs should be improved in terms of qualifications of teachers, tools, practicum materials, and the use of learning models as per industry needs. This study aims to evaluate the used curriculum of light vehicle engineering department as per industry needs. This study uses discrepancy evaluation model (design, installation, process, product and comparison) that describes the implementation of curriculum according to the industry needs from various aspects, namely: design, installation, process, product and comparison. The study results concluded that achievement level of curriculum implementation as needed in the design component obtained an average score of 4.28 (83.17%) classed in a good category; installation components get an average score of 3,502 (78.47%) classified in sufficient categories; process components get an average score of 4.05 (81.75%) classed in a good category; and product components that scored an average of 4.02 (81.26%) classified in a good category. As well as in the comparison component that obtained an average score of 3,324 (74.27%) classified in sufficient categories. The implementation of vocational school curriculum majoring in light vehicle engineering as a whole is categorized as sufficient. Therefore, it needs a follow-up from the relevant parties for a better implementation.; one of which is by revising the curriculum to fit the needs of the industry.
The Suitability of Students in Bachelor of Science in Statistics (BSS) Program
Authors: Casinillo Leomarich F. , Miñoza Susana B
Published: January 2021

This study aims to assess the suitability of students in Bachelor of Science in Statistics program. Seemingly, several students who enrolled in the said program does not possess the qualities of being mathematically inclined. Hence, this study was conducted.  By complete enumeration, the study employed all BSS students from different year level. Secondary data were used such as two psychological tests from the University Student Services Office which measures the intelligence and numerical aptitude.  A primary data was also employed through an instrument called Brainard Occupational Preference Inventory which measures the interest of students in the field of statistics. The gathered data were then analyzed with the aid of some descriptive measures and correlational methods. Results revealed that there are only a few (11.9%) who have high levels of intelligence and numerical aptitude but they happen to have low level of interest in statistics. Of those students highly interested (47.6%) in the field of statistics one-fourth (11.9%) of them have low levels of intelligence and numerical aptitude. It is found out that there is a significant linear relationship between intelligence and numerical aptitude among BSS students. Moreover, intelligence and interest in statistics is inversely and significantly correlated among BSS junior students. Furthermore, results showed that there is no significant linear relationship between numerical aptitude and interest in statistics across year level. Hence, the interest of the BSS students must be cultivated in order to increase their level of achievement.
Needs Analysis of Blended Learning Development on Instructor Training at Basarnas
Authors: Abdillah Adi , Solihatin Etin , W R.A Murti Kusuma
Published: January 2021

Blended learning facilitates learning by providing various learning resources and considering the characteristics of learners. This study aims to conduct a needs analysis for the development of blended learning in instructor training at Basarnas. Needs analysis is carried out to explore information about gaps and needs as well as student profiles that can be used as a basis or reference in developing blended learning at the next stage. This research is a descriptive study with quantitative approach. Data collection was carried out by means of observation, interviews, and distributing questionnaires. Interviews were conducted with the Head of the Sub-Directorate for Planning and Standardization of Basarnas Personnel, while the filling of the questionnaire was carried out by the Basarnas Rescuer who will attend instructor training as many as 50 respondents. The results show that instructor training at Basarnas can be designed in the form of blended learning by using a project-based learning approach to overcome existing limitations or gaps so that the implementation of blended learning that combines the delivery of face-to-face learning and online learning can be an intervention that is suitable to be applied and appropriate. with the needs at Basarnas.
Needs Analysis of The Traffic Safety Training Hyper Content Module at The Ministry of Transportation
Authors: Komalasari Lina , Muslim Suyitno , Winarsih Murni
Published: January 2021

Traffic safety training whose material needed a concrete visualization aspect. To accommodate this, teaching materials were needed to support the learning process. This study aims to describe the results of needs analysis which is the first step of the Research & Development process conducted with a qualitative approach. Data collection techniques are done by conducting research through documentation, observation, and interviews. The results of the needs analysis have been found several problems, that is the heterogeneous characteristics from training participants, limited experience of training participants, limited training time, lack of teaching materials, and training implementation locations throughout Indonesia. Hyper content-based printing modules are a great alternative because they can bring related factual aspects of traffic safety to training participants. In the next research, it is expected to develop a hyper content-based traffic safety training module.
PENGARUH LATIHAN PLYOMETRIK MELOMPATI KUN DENGAN DUA KAKI KE SAMPING, SECARA ZIG-ZAG PADA SISWA PUTRA KELAS VIII A
Authors: Amrizal Amrizal , Siska Siska
Published: January 2021

This study aims to determine whether there is 1) The effect of plyometric training jumping over a kun with two legs to the side, 2) The effect of the plyometric training jumping over a kun with two legs in a zig-zag manner, 3) Comparison of the plyometric exercise jumping over a kun with two legs sideways and in a zig-zag manner on leg muscle power for male students of class VIII A SMP Negeri 1 Rambah, Rokan Hulu Regency. This type of research is a quasi experiment. The population was all male students of class VIII A SMP Negeri 1 Rambah, Rokan Hulu Regency, totaling 12 people. The sampling technique used in this study was total sampling, namely the entire population of male students of class VIII A SMP Negeri 1 Rambah, Rokan Hulu Regency. The instrument used in collecting data was the Standing Broad Jump test. The data analysis technique used was the t-test, where 1) The effect of the plyometric training jumping over a kun with two legs to the side is 4.27, 2) The effect of the plyometric training jumping over a kun with two legs in a zigzag manner is 5.97, 3) Comparison plyometric exercise jumping kun with two legs to the side and zigzag the leg muscle power of male students class VIII A SMP Negeri 1 Rambah, Rokan Hulu Regency is 2.36 with t table is 1.81. So from the two exercises given there are significant differences.
STUDI KETERAMPILAN TEKNIK DASAR SEPAKBOLA SISWA SMP NEGERI 3 KOTA PADANG
Authors: . Erianti , Astuti Yuni , . Zulbahri , . Damrah , . Kibadra
Published: January 2021

The problem in this study is that the basic technical skills of student football are not yet known at SMP Negeri 3 Kota Padang. So the purpose of this study was to determine the basic technical skills of student football at SMP Negeri 3 Padang, which consisted of passing, dribbling, shooting and heading techniques. This type of research is descriptive. The population in this study were all students of SMP Negeri 3 Kota Padang who actively participated in soccer training in football extracurricular activities, totaling 22 people. The sampling technique uses total sampling. Thus the sample in this study amounted to 22 people. To obtain data, measurements are made on the basic technical abilities of football. Data were analyzed using percentages. The results found that: the basic technical skills of football students of SMP Negeri 3 Kota Padang, it can be said that there are still many who have not been good, because of 22 students only 1 person (4.54%) category is very good, 7 people (31.82%) good category, and 2 people (9.09%) medium category. The rest students have less basic technical skills in soccer categories, namely 12 people (54.54%).Keywords: Basic Football Techniques.
MOTIVASI MENGIKUTI PEMBELAJARAN PENDIDIKAN JASMANI, OLAHRAGA DAN KESEHATAN PESERTA DIDIK SMA/SMK DI KECAMATAN RENDANG DI MASA PANDEMI COVID-19
Authors: Kustria Kadek Satria , Agung Parwata I Gusti Lanang , Spyanawati Ni Luh Putu
Published: January 2021

Penelitian ini bertujuan untuk mengetahui motivasi mengikuti pembelajaran Pendidikan Jasmani, Olahraga dan Kesehatan peserta didik SMA/SMK di Kecamatan Rendang di masa pandemik covid-19. Penelitian ini merupakan penelitian deskriptif kuantitatif dan metode dalam penelitian ini adalah metode survei. Populasi dalam penelitian ini seluruh peserta didik di SMA/SMK di Kecamatan Rendang dengan jumlah populasi 1.257 orang dan di pilih kelas secara random sampling. Sampel penelitian ini berjumlah 253 orang. Data dianalisis menggunakan statistik dengan persentase. Hasil penelitian ini menunjukan bahwa motivasi mengikuti pembelajaran Pendidikan Jasmani, Olahraga dan Kesehatan peserta didik SMA/SMK di Kecamatan Rendang di masa pandemik covid-19 yaitu berada dalam kategori tinggi yaitu 78 orang (30,83%). Disarankan bahwa agar kedepannya guru Pendidikan Jasmani, Olahraga dan Kesehatan dapat mengemas proses pembelajaran di masa pandemik covid-19 lebihbaik dan bervariatif dalam melaksanakan proses pembelajaran daring. Kata Kunci: motivasi, pembelajaran PJOK, pandemi covid-19.
MOTIVASI MENGIKUTI PEMBELAJARAN PJOK PESERTA DIDIK SMA DI KECAMATAN BANGLI DALAM PEMBELAJARAN DARING
Authors: Wiraguna I Nengah , Agung Parwata I Gusti Lanang , Semarayasa I Ketut
Published: January 2021

Penelitian ini bertujuan untuk mengetahui motivasi mengikuti pembelajaran PJOK peserta didik SMA di Kecamatan Bangli dalam pembelajaran daring. Penelitian ini merupakan penelitian deskriptif kuantitatif dengan metode survei. Populasi dalam penelitian ini adalah peserta didik SMA di Kecamatan Bangli. Sampel ditentukan dengan menggunakan teknik random sampling. Data dianalisis menggunakan teknik statistik dengan presentase. Hasil dari analisis data, didapatkan bahwa motivasi peserta didik  mengikuti pembelajaran PJOK di SMA Negeri 1 Bangli berada pada kategori sangat tinggi dengan persentase sebesar 31,09%. Sedangkan pada peserta didik SMA Negeri 2 Bangli motivasi peserta didik berada pada kategori sangat tinggi dengan persentase sebesar 37,50%. Dari hasil analisis secara keseluruhan, motivasi peserta didik adalah sebesar 41,18% dengan kategori motivasi sangat tinggi . Dari data motivasi yang telah dianalisis, hasil penelitian menunjukan bahwa motivasi mengikuti pembelajaran PJOK peserta didik SMA di Kecamatan Bangli dalam pembelajaran daring berada dalam kategori sangat tinggi. Kata Kunci: Motivasi, PJOK, pembelajaran daring.
Memory from a pragmatic point of view: intersections of Merleau-Ponty and Francisco Varela
Authors: Araujo Arthur
Published: January 2021

Tendo como fundo uma concepção pragmática de memória como fazer sem representar, o artigo explora a interseção entre Merleau-Ponty e Varela na qual a noção de condição corporal assume uma função distintiva. A ideia é que a memória depende da condição corporal como um todo e, por consequência, nada tem a ver com representação. O objetivo do artigo pode ser resumido nos seguintes termos: para um organismo, pragmaticamente, é vital saber como fazer coisas com suas memórias mais do que torná-las representações internas do mundo.