bluuebunny/crossref_metadata_2025 huggingface dataset:
Digital transformation of ultrasound diagnostics.
Authors:   the Department of Innovative Development and Scientific Design of the Central Research Institute of Organization and Informatization of Health Care of the Ministry of Health of the Russian Federation, Lebedev G.S. ,   Moscow, Russia, Shaderkin I.A. ,   the Laboratory of Electronic Health, Institute of Digital Medicine, Sechenov University; Moscow, Russia, Shaderkina A.I. ,   Institute of Clinical Medicine, department «Personalized medicine» of the First Moscow State Medical University named after I.M. Sechenov (Sechenov University); Moscow, Russia
Published: March 2023

Introduction. Ultrasound (US) is one of the most applied diagnostic methods in the medicine due to its accessibility and non-inva- siveness. Twice more ultrasound examinations are conducted in Russia then in economically developed countries. It is necessary to increase the efficiency of ultrasound and optimization of data management because of its significant impact on diagnostics and high load on the US method. In this paper we provide the ways digital technologies have influence on the ultrasound. Materials and methods. The search was conducted via Pubmed database and the Internet open sources. Results. Based on the conducted research, we can separate apply of tele-ultrasound into several directions: using in the remote and resource-limited towns and areas; in the emergency care; in the situations with limited time or access to the medical care, for instance, in space; in obstetrics; for home monitoring by patients or their relatives; and for medical staff training. Routine two-steps algorithm of ultrasound examination can be divided to discrete stages with new technological solutions and participants, including artificial intelligence: data obtaining, saving, transfer and analysis, cloud storage and patient’s access to it at any time. Conclusion. Ultrasound is an actively developing sphere of instrumental diagnostics and on the current stage there are enough instruments for its digital transformation. The appearance of portable and handheld US devices, development of standardized pro- tocols and POCUS implementation in routine clinical practice, and use of ultrasound robots allows to minimize such disadvantages of US as its operator-dependance and subjectivity of examinations. The development of systems for data transfer and storage leads to broadening of ultrasound data management possibilities, for example, datasets creation, data sharing with other specialists and tele ultrasound implementation which widens access to medicine in resource-limited areas.
Development of digital technologies and medical products during the period of sanctions.
Authors:   the Laboratory of Electronic Health, Institute of Digital Medicine, Sechenov University, Shaderkin I.A. ,   Moscow, Russia, Shaderkina V.A. ,   the urological information portal UroWeb.ru
Published: March 2023

After February 24, 2022, a number of countries imposed sanctions on Russia - political, financial, energy, technological, transport and logistics, and personal. At the time of writing, Russia is the country with the largest number of sanctions against it in world history. We reviewed the de- velopment of digital technologies and medical equipment during the period of sanctions, the adaptation of Russian developers, scientists, doctors to sanctions, as well as the prospects and forecasts for the impact of sanctions on the development of telemedicine. The article deals with the issues of export and import of telemedicine solutions, changes in personnel (scientists, developers, program- mers, engineers, doctors, patients) and legal structures, access to resources for the creation and development of telemedicine tech- nologies (consumables, libraries, development environments, etc. .). Models of investments in telemedicine technologies – venture and dividend ones - are analyzed, and the prevailing one is determined. Attention is paid to adaptation to the sanctions that began to form compensatory over the past year. Despite the fact that the sanctions have a negative focus, for the Russian TM industry, this can be a good incentive for development. Russian developers have every chance to create unique domestic solutions for telemedicine technologies that will improve the availability and quality of medical care for Russian patients.
ATIVIDADE DO GENE LRRK2 NA DOENÇA DE PARKINSON: UM A REVISÃO DE LITERATURA
Authors: Souza Murilo Dos Santos , Souza Isabela De Nazaré Tavares Cardoso , Souza Pablo Rodrigues Nunes de , Oliveira Rita de Cassia Silva de
Published: March 2023

INTRODUÇÃO: A doença de Parkinson (DP) é um distúrbio neurodegenerativo com alta prevalência entre idosos, sua principal causa corresponde à degeneração dos neurônios dopaminérgicos da substância negr
Relativização do Controle concreto de Constitucionalidade
Authors:   , Pontes Bianca de Melo
Published: March 2023

O presente trabalho monográfico objetiva abordar a moderna tendência de aproximação da eficácia da decisão proferida em sede de controle concreto de constitucionalidade àquela tradicionalmente atribuída ao controle abstrato. A doutrina clássica atribui eficácia inter partes e sem vinculação à decisão em controle concreto de constitucionalidade. Todavia, vem sendo observado um processo de abstrativização legislativa e judicial da análise concreta, atribuindo-se a esta os efeitos próprios do modelo abstrato, gerais e vinculantes. O presente estudo visa demonstrar as diversas manifestações dessa tendência de abstrativização, bem como os fundamentos que dão suporte à sua ocorrência.
Theoretische und empirische Dimensionen eines kritisch-psychologischen Begriffs kollektiver Handlungsfähigkeit
Authors: Reimer-Gordinskaya Katrin , Tzschiesche Selana
Published: March 2023

In diesem Artikel werden ausgehend vom kritisch-psychologischen Begriff der personalen Handlungsfähigkeit Grundlagen und Dimensionen eines Begriffs kollektiver Handlungsfähigkeit entwickelt. Auf der Basis eigener Forschung zu Antisemitismus und Klassismus werden dazu Formen des Zusammenschlusses mit Blick auf die Reichweite und den Organisationsgrad unterschieden und veranschaulicht. Zudem wird unter Bezug auf marxistische Beiträge zur Organisierung von subalternen Gruppen diskutiert, wie die Verbreiterung der sozialen Basis und Verallgemeinerung von Interessen im Übergang von ökonomischer zu politischer Interessenvertretung gefasst werden kann. Dabei werden Geschlechterverhältnissen und Migrationsregimen/Rassismus als integrale Momente von Klassenverhältnissen verstanden und Antisemitismus als eine systematische Leerstelle der Analyse und Konzipierung kollektiver Handlungsfähigkeit benannt.
Research on the Effects of Chemotherapy on Survival Outcomes for Older Patients with Primary Triple-Negative Breast Cancer after Surgery: A Propensity Score Matching and Competing Risk Analysis of the SEER Database
Authors: He Chongwu , Chen Jing , Hu Bing , Jiang Ming , Chen Ru , Li Jianglong , Wang Gongxian , Yu Tenghua
Published: March 2023

Background: The population of older women (≥70 years old) with triple-negative breast cancer (TNBC) is increasing, but there are few prognostic studies for these patients. In the study, we explored the effects of chemotherapy on breast cancer-specific death (BCSD) and other cause-specific death (OCSD) in older patients with TNBC. Methods: In accordance with the inclusion and exclusion criteria, we extracted primary TNBC older patients (≥70 years old) from the Surveillance, Epidemiology, and End Results (SEER) database from 2010 to 2019. We used propensity score matching (PSM), cumulative incidence function (CIF) and multivariate Fine and Gray competitive risk analyses to explore the effects of chemotherapy on survival for older patients with primary TNBC after surgery. Results: After one-to-one matched PSM analysis, we identified 2478 primary TNBC patients (≥70 years old) finally. CIF analysis showed that the 3-year, 5-year and 8-year mortalities were 15.34%, 20.30% and 23.73% for BCSD, and 7.36%, 13.20% and 23.02% for OCSD. The survival analysis showed that patients who received chemotherapy had a better overall survival than those who did not received chemotherapy (hazard ratio 0.72, 95% confidence interval 0.63–0.82, p < 0.001). There was no difference in BCSD between older patients with chemotherapy and no chemotherapy. The OCSD rate for patients with chemotherapy was lower than that of those with no chemotherapy (Gray’s test, p < 0.001). Diseases of heart were the most common cause of death in elderly patients with TNBC. After multivariate Fine and Gray competitive risk, age in diagnosis, race black, tumor grade, T status, N status and receiving radiotherapy were proven to be independent predictive factors of BCSD. Meanwhile, age in diagnosis, radiotherapy status, and chemotherapy status were proven to be independent predictive factors of OCSD. Conclusions: For older patients (≥70 years old) with TNBC, chemotherapy improved overall patient survival by reducing the rates of OCSD, but not by reducing the rates of BCSD. The impact of non-cancer causes of death on the prognosis of older cancer patients should not be ignored.
Non-Electrical Ligation of Vessels Using Hem-o-lok Clips Ensures No Electrical Ureteral Injury during Total Laparoscopic Hysterectomy
Authors: Kim Sang Il , Lee Sung Jong , Yoon Joo Hee
Published: March 2023

Background: Ureteral injury is one of the most common anatomical complications during total laparoscopic hysterectomy (TLH). And most ureteral injuries resulted from electrosurgery and were recognized postoperatively. To avoid thermal damage to the ureter during TLH, we evaluated the feasibility and safety of vessel ligation using the Hem-o-lok clip. Methods: A retrospective analysis of 480 patients who underwent TLH. Hem-o-lok clips were used to ligate both uterine vessels. If the patient underwent unilateral or bilateral salpingo-oophorectomy, the gonadal vessels were also ligated by using Hem-o-lok clips. Clinical outcomes including perioperative and postoperative complications were evaluated. Results: Perioperative complications were reported in six patients, with four cases of stump dehiscence and two cases of bladder injury. All bladder injuries were found during the operation and repaired. None of the patients experienced ureter injury or vessel rebleeding. Conclusions: Vessel ligation by Hem-o-lok clips in TLH is a safe method for ligating vessels and avoiding unexpected ureteral injury. Prospective studies are needed to confirm the real clinical benefit of this surgical approach.
Physiological and Proteomic Analysis of Seed Germination under Salt Stress in Mulberry
Authors: Wang Yi , Jiang Wei , Cheng Junsen , Guo Wei , Li Yongquan , Li Chenlei
Published: March 2023

Background: Salinity is the main abiotic stress that affects seed germination, plant growth and crop production. Plant growth begins with seed germination, which is closely linked to crop development and final yields. Morus alba L. is a well-known saline-alkaline tree with economic value in China, and the most prominent method of expanding mulberry tree populations is seed propagation. Understanding the molecular mechanism of Morus alba L. salt tolerance is crucial for identifying salt-tolerant proteins in seed germination. Here, we explored the response mechanism of mulberry seed germination to salt stress at physiological and protein omics levels. Methods: Tandem mass tag (TMT)-based proteomic profiling of Morus alba L. seeds germinated under 50 mM and 100 mM NaCl treatment for 14 days was performed, and the proteomic findings were validated through parallel reaction monitoring (PRM). Results: Physiological data showed that salt stress inhibited the germination rate and radicle length of mulberry seeds, decreased the malondialdehyde (MDA) content and significantly increased superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) activities. Then, a TMT marker technique was used to analyze the protein groups in mulberry seeds with two salt treatment stages, and 76,544 unique peptides were detected. After removing duplicate proteins, 7717 proteins were identified according to TMT data, and 143 (50 mM NaCl) and 540 (100 mM NaCl) differentially abundant proteins (DAPs) were screened out. Compared with the control, in the 50 mM NaCl solution, 61 and 82 DAPs were upregulated and downregulated, respectively, and in the 100 mM NaCl solution, 222 and 318 DAPs were upregulated and downregulated, respectively. Furthermore, 113 DAPs were copresent in the 50 mM and 100 mM NaCl treatments, of which 43 were upregulated and 70 were downregulated. Gene Ontology (GO) annotation and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis revealed that the DAPs induced by salt stress during mulberry seed germination were mainly involved in photosynthesis, carotenoid biosynthesis and phytohormone signaling. Finally, PRM verified five differentially expressed proteins, which demonstrated the reliability of TMT in analyzing protein groups. Conclusions: Our research provides valuable insights to further study the overall mechanism of salt stress responses and salt tolerance of mulberry and other plants.
Biophotonic intra-objectivity test: A giant leap toward the intermediary collapse of scientific method
Authors: Gadda Navjot Singh
Published: March 2023

A test for subjectivity, proto-subjectivity, semi-objectivity, semi-subjectivity, inter-subjectivity and intra-objectivity is easily obtained via this experiment.
Pendidikan multikultural dan multikulturalisme
Authors: senda Arbianur
Published: March 2023

Pendidikan Multikulturalisme di Indonesia harusnya menggali nilai SARA dan kebudayaan peserta didik sebagai keyakinan mereka yang mengajarkan kalau perbedaan adalah takdir Tuhan. Dalam perbedaan rasa cinta dan kasih sayang sesama harus terus dikembangkan. Pendidikan mampu menciptakan sikap toleransi, saling menolong dengan pembelajaran yang memiliki visi dan tindakan pembiasaan di semua satuan pendidikan. Pendidikan Multikultural berpusat pada karakter ke Indonesiaan, dapat disimpulkan bahwa pembelajaran Mmultikultural ini dilakukan dengan pembentukan pola pikir, sikap, tindakan, dan pembiasaan sehingga muncullah kesadaran nasional yang berkarakter. Terwujudnya karakter keindonesiaan menjadi landasan sebagai ciri khas manusia Indonesia. Kekuatan keindonesiaan menjadi energi untuk menjadi Indonesia sebagai bangsa besar di tengah percaturan bangsa-bangsa didunia. Bangsa besar hanya dapat diwujudkan melalui karakter manusia yang kuat.
Pendidikan Multikultural
Authors: Purba Marta Sari
Published: March 2023

PENDIDIKAN MULTIKULTURAL DI INDONESIA: ANALISIS SINKRONIS DAN DIAKRONISOleh:Okta Hadi Nurcahyono1AbstrakProses pendidkan tidak terlepas dari stuktur sosial dan perkembangan masyarakatnya, begitu juga pada pendidikan multikulturalisme. Pendidikan multikultural merukpakan fenommena baru dalam dunia pendidikan, sehingga menjadi daya tarik untuk diperbincangkan dalam forum-forum ilmiah seperti seminar, workshop, simposium dan sebagainya. Artikel ini memaparkan proses dan jalan panjang dan perkembangan pendidikan multikulturalisme di Indonesia. Ada dua pendekatan yang digunakan penulis dalam menganalisis perkembangan pendidikan multikultural di Indonesia yaitu dengan pendekatan sinkronis dan pendekatan diakronis. Dalam pendekatan sinkronis, ditemukan bahwa pendidikan multikultural di Indonesia lahir dari perjalanan panjang yang terbagi menjadi tiga fase yaitu: Fase segregasi pada masa kolonial, fase pendidikan yang bercorak melting pot pada masa orde baru, dan fase pendidikan multicultural dengan semangat demokrasi pada masa reformasi. Sedangkan pada analisis diakronis, pendidikan multikultural yang ada di Indonesia sekarang ini tidak lepas dari sejarah dimasa lampau, yaitu semboyan “Bhinneka Tunggal” sebagai politik kebudayaan di jaman Kerjaan Majapahit dan Peristiwa reformasi yang melahirkan demokrasi dengan menjujung tinggi persamaan hak pada setiap warga negara khususnya dalam mengaks
Responsible Research Assessment requires structural more than procedural reforms.
Authors: Frischkorn Gidon T.
Published: March 2023

In their target articles, Schönbrodt et al. (2022) and Gärtner et al. (2022) propose new metrics and their practical implementation to improve responsible research assessment. Generally, I welcome the inclusion of open science and scientific rigor into evaluating job candidates. However, the proposed reform mainly focuses on the first stage of selecting candidates who then continue towards a second stage of in-depth evaluation of research quality. Yet, this second selection stage is underdeveloped but likely more critical concerning responsible research assessment and hiring decisions. I argue that an adequate assessment of research quality at this second stage requires the representation of specific knowledge in the subfield of a discipline that the candidate should be hired for by the hiring committee. This is rarely achieved given the current structural organization of departments, especially in German-speaking countries, and potentially explains the reliance on suboptimal indicators such as h-index and Journal Impact factor. Therefore, I argue that responsible research assessment requires structural reform to ensure that institutions have several researchers in permanent positions with specific knowledge in different subfields to provide an adequate and responsible assessment of research quality by hiring committees at all evaluation stages.
Cognitive control and semantic thought variability across sleep and wakefulness
Authors: Mallett Remington , Nahas Yasmeen , Christoff Kalina , Paller Ken A. , Mills Caitlin
Published: March 2023

The flow of thought is persistent, and at times merciless. Mental content is generated throughout the day and into the night, moving forward predictably at times but surprisingly at others. Understanding what influences the trajectory of thought—how thoughts continuously unfold over time—has important implications for the diagnosis and treatment of thought disorders like schizophrenia and recurrent nightmares. Here, we examine whether cognitive control restricts moment-to-moment content shifts across sleep and wakefulness, thus acting as a fundamental constraint on thought variability. Thought variability was measured as the semantic incoherence between sequential thought phrases and was applied to independent datasets of dreaming and waking reports. Our results show that within both sleeping and waking reports, conditions typically marked by higher levels of cognitive control were associated with decreased thought variability (i.e., semantic incoherence). During wakefulness, on-task conditions were associated with reduced levels of thought variability compared to off-task conditions, and thought variability was greater when thoughts wandered around more freely. During sleep, lucid dreams, marked by higher levels of cognitive control, were associated with reduced levels of thought variability compared to non-lucid dreams. Together, these results suggest that cognitive control may limit thought variability across the 24-hour cycle of thought generation. Such findings are consistent with the Dynamic Framework of Thought, where mental states are expected to vary on a continuum of deliberate constraints, with lower cognitive control leading to a categorical cluster of spontaneous thought processes that includes both mind-wandering during wakefulness and non-lucid dreams during sleep. This observation has broad implications for models of cognition, specifically highlighting the continuity of cognitive processes throughout the circadian cycle and the importance of considering varying levels of thought constraint in both waking and dreaming states.
Incidence of Birth Defects among Live Born Neonates at Tertiary Level Maternity Hospital in Nepal
Authors: Shakya Shristi , Upadhaya Subedi Kalpana , Mishra Megha
Published: March 2023

Introduction: Birth defects are structural and functional anomalies that present before, at birth, or later in life. This study aimed to find out total incidence, type of structural birth defects in live born babies in Nepal.
Methods: The study was conducted at a tertiary level maternity hospital in Nepal from 14 April 2018 to 13 April 2019. Data was collected on online Newborn Birth Defect data base developed by WHO South- East-Asia Regional Office. All live born babies with external and internal birth defects confirmed by radiographic, ultrasonography and echocardiography until seven days of life were included. Ethical approval was obtained from Institutional Review Committee of hospital.
Results: Total of 21,564 live babies were delivered during one-year study period. Out of these, 220 (1.02%) had one or more birth defects. Number of male babies {130 (59%)} were more than female {89 (40.9%)}. 176 (80%) babies with the malformation were born to mother within age group 20 to 35 years. Of the total 220 babies with birth defects, 197 (89.5%) had isolated malformations and remaining 23 (10.4%) had sequence malformations. The most frequent malformations involved cardiovascular system 125 (56.8%) followed by gastrointestinal system 37 (16.8%), musculoskeletal system 34 (15.4%) and central nervous system 18 (8.1%).
Conclusions: Incidence of overall birth defects in this study was found to be 1.02% in which cardiovascular system anomalies was the most common followed by gastrointestinal, musculoskeletal and central nervous system anomalies.
Acute Kidney Injury Secondary to Abdominal Tuberculosis: A Diagnostic Dilemma - A Case Report
Authors: Yadav Bharti , Richa  , Sadadiwala Shikha , Singh Manimukta
Published: March 2023

Tuberculosis is a serious public health issue in developing countries. Hypercalcemia, though reported in granulomatous disease, is mild and asymptomatic in tuberculosis. A 16 year old girl female presented with significant weight loss, loss of appetite and on examination hepatosplenomegaly. Ultrasound abdomen (USG) showed mesenteric and retroperitoneal lymphadenopathy with hepatosplenomegaly with mild ascites. We report an unusual case of hypercalcemia with renal injury due to abdominal tuberculosis in an immunocompetent female.
Association between Serum Magnesium to Calcium Ratio with Level of Asthma Control in Children
Authors: Kundu Tapan Kumar , Dutta Arpan , Chatterjee Abhilash , Chowdhury Aditi
Published: March 2023

Introduction: Bronchial asthma is an inflammatory reversible obstructive airway disease. This study aims to determine the association between serum magnesium to calcium ratio with level of asthma control in children by comparing serum magnesium to calcium ratio between - children with well controlled, partly controlled and uncontrolled asthma.
Methods: An analytical cross sectional study was done on 90 children diagnosed with bronchial asthma between five to 12 years age from January 2019 to June 2020. Children were selected from the outpatient and inpatient departments of paediatric medicine of a tertiary care medical college hospital. They were classified into well controlled, partly controlled and uncontrolled groups as per Global Initiative for Asthma (GINA) assessment of asthma control in children. The serum magnesium to serum calcium ratio of these children were compared between the groups classified.
Results: Mean level of serum magnesium to calcium ratio in well controlled group was 0.29857 (SD 0.07633), partly controlled 0.2439 (SD 0.0532), uncontrolled 0.2545 (SD 0.04467), respectively. Serum magnesium to calcium ratio more than or equal to 0.3 was positively correlated with well controlled asthma. Comparisons of serum magnesium to calcium ratio of well controlled group with partly controlled, uncontrolled and both partly and uncontrolled were statistically significant.
Conclusions: Higher serum magnesium to calcium ratio is associated with well controlled asthma. In our study, serum magnesium to calcium ratio more than 0.3 is significantly associated with well controlled asthma.
Prevalence of Cleft Lip and Palate in the Developing Countries of Asia and Africa: A Review
Authors: Shrestha Ashish , Hoang Ha , Gardner Sue , Pradhan Archana , Crocombe Leonard
Published: March 2023

Introduction: The objective of this paper is to review the literature on the incidence of cleft lip and palate (CLP) in the developing countries of Asia and Africa. The existing literature tends to focus on developed countries and there is lack of research in developing countries.
Methods: The studies that met the inclusion criteria were reviewed and data extracted. There were 20 studies done in Asian and African countries which were included.
Results: The incidence of CLP in Asian countries is markedly greater than in African countries. Most studies report a male predominance in CLPs and a female predominance in cleft palates. The male dominance is seen more than other developing countries which is consistent with other Asian countries and the same has been found in African countries. In the Nepalese study, females were slightly more affected than males among all clefts. The incidence or prevalence in the frequency and types of malformations of CLP in developing countries has been provided.
Conclusions: The review underlines the need for an aggressive approach to prevent and control CLP in patients in developing countries.
Practical issues for conducting qualitative research
Authors: Priya Pushpa
Published: March 2023

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Efeito da depressão na autoestima real e ideal: um estudo com o IRAP
Authors: Ruiz Márcio Luiz de Araújo , De Almeida João Henrique , Haydu Verônica Bender
Published: March 2023

Este estudo visou comparar as respostas relacionais de autoestima real e ideal por meio do Implicit Relational Assessment Procedure (IRAP) e explorar a correlação entre a pontuação dos participantes na Escala de Autoestima de Rosenberg (EAR) e os escores D-IRAP. Participaram do estudo 20 adultos, distribuídos em dois grupos, com e sem depressão. O procedimento teve duas fases: (a) aplicação do BDI-II e do EAR, (b) aplicação do IRAP autoestima real e do IRAP autoestima ideal. Os resultados mostraram que participantes com depressão diferem de participantes sem depressão quanto a autoestima avaliada pelo EAR e apresentaram similaridades na avaliação pelo IRAP. Participantes com depressão apresentaram: vieses negativos de autoestima real e vieses positivos de autoestima ideal. Os participantes sem depressão não apresentaram diferenças quanto a autoestima real e a ideal.
Analysis of Breast Cancer Data using Kaplanâ€“Meier Survival Analysis
Authors: Dakhil Nazera Khalil , Alâ€“mayali Yahya Mahdi , Alâ€“A'bidy Muna Abbas
Published: March 2023

The Kaplanâ€“Meier estimator is a very popular that provides better estimates to determine the median when the sample size is reasonably large. The aim of this research was mainly concerned with a study and analysis an
ON almost Tl- continuous multifunctions
Authors: Mustafa Hadi Jaber , Mohsin Muayad Ghazi
Published: March 2023

Using the concept of T- open set we introduce and study the concept ofÂ  Almost T - continuous multifunctions which is stronger than the concept of Almost - continuous multifunctions. SeveralÂ  propertiesÂ  and characterizations of this new concept are proved .
A new procedure of initial boundary value problems using homotopy perturbation method
Authors: Jassim Abeer Majeed , Ali Elaf Jaafar , Ahmed Afrah Abd-Imam
Published: March 2023

In this paper, , a new procedure is applied to treatment of initial boundary value problems by mixed initial and boundary conditions together Â to obtain a new initial solution at every iteration using homotopy perturbation method. The structure of a new successive initial solutions can give a more accurate solution. Some examples (linear and nonlinear, homogeneous and nonhomogeneous problems) are given in this paper to illustrate the effectiveness and convenience of a new procedure.
Smarandache Completely Semi Prime Ideal With Respect To An Element Of A Near Ring
Authors: Abass Hussien Hadi , Ebraheem Showq Mhammed
Published: March 2023

In this paper ,we introduce the notions of smarandache completely semi prime ideal (S.C.S.P.I),and smarandache completely semi prime ideal with respect to an element x of a near ring N denoted by (x-S.C.S.P.I) , and smarandache completely semi prime ideal with respect to an element x near ring .Also we give some properties of these notions
A New Algorithm For Solving Transportation Problem With Network Connected Sources
Authors: S. Aljanabi Kadhim B. , Jasim Anwar Nsaif
Published: March 2023

Solving transportation problems where products to be supplied from one side(sources) to another (demands) with a goal to minimize the overall transportation cost represents an activity of great importance. Most of the works done in the field deals with the problem as two-sided model (Sources such as factories and Demands such as warehouses) with no connections between sources or demands.

However, real world transportation problems may come in another model where sources are connected in a network like graph in which each source may supply other sources in a specific cost. The work in this paper suggests an algorithm and a graph model with mathematical solution for finding the minimum feasible solution for such widely used transportation problems. In this work, the graph representing the problem in which all sources are connected together in a network model with specific cost on each edge is converted into a new graph where additional virtual sources representing supplies between sources are added to the graph , new costs between the added sources and the demands are also calculated, and then modified Kruskalâ€™s algorithm is applied to get the minimum feasible solution.

The proposed solution is a straight forward model with strong mathematical and graph models. It can be widely used for solving real world transportation problems with feasible time and space complexity where time complexity of O(E2 + V2) is required, where E represents the number of edges and V represents the number of vertices. Different numerical examples were used to study the effectiveness and correctness of the proposed algorithm.
Ismael Cosío Villegas. Principales acciones contra la tuberculosis en México, 1929–1965
Authors:   Universidad Nacional Autónoma de México, García Vega Verónica , Martínez Barbosa Xóchitl ,   Universidad Nacional Autónoma de México
Published: March 2023

The article is a biographical study centered around the professional development of the Mexican pulmonologist Ismael Cosío Villegas (1902–1985), through which we address and understand tuberculosis care practices in Mexico during the first half of the 20th century. Important health actions are owed to Ismael Cosío Villegas in the fight against this disease, so his contribution to medicine is recognized for the work dedicated to the care of tubercu-losis patients and respiratory diseases. The biography proposed here derives mainly from the interview made to Dr. Cosío Villegas by the ‘Oral History’ program in 1977 and from the documents related to his professional career. The purpose of this study is to demonstrate the incidence that Ismael Cosío Villegas had in 20th century Mexican medicine.
ДИДАКТИЧНО-ДЕМОКРАТИЧНА ПАРАДИГМА НАВЧАННЯ ХОРЕОГРАФІЇ У БРИТАНСЬКОМУ ДОСВІДІ
Authors: БІДЮК ДМИТРО
Published: March 2023

Стаття присвячена розкриттю дидактичних особливостей професійної підготовки хореографів у досвіді Великої Британії. З’ясовано, що британські педагоги беруть до уваги нові теорії синтезу музичного й танцювального мистецтва, танцювальної та цифрової педагогіки, хореографії, спорту. Охарактеризовано «дидактично-демократичну модель» («didactic-democratic spectrum») навчання, яка визнана новою парадигмою навчання хореографічного мистецтва, що ґрунтована на соціально-мистецьких взаєминах між хореографом і виконавцем (нові ролі хореографа й виконавця: «експерт – виконавець», «постановник – транслятор», «фасилітатор – творець», «співавтор – співвиконавець», «художник – оповідач» та ін.). Обґрунтовано, що дидактичний складник охоплює навчання хореографії на засадах принципу «навчи показуючи» («teaching by showing»), а демократичний – процес навчання на основі співпраці, партнерської взаємодії («collaborative dance learning»). Встановлено, що «дидактичний» концепт стосується не лише навчального елемента «навчання через показ», але й розвитку навичок учіння. «Демократичний» концепт відображений в соціальному характері танцю, відтінках демократичної рівності в танці на засадах партнерства й толерантності. Представлено механізм поетапної реалізації й змістове наповнення дидактично-демократичної моделі навчання хореографії. Модель сприяє посиленню взаємозв’язку теоретичного й практичного навчання на основі фасилітації, незалежної експертизи навчання хореографії, демократичного стилю викладання, урахування особистого досвіду студента та викладача, рефлексії й саморегуляції, принципів соціальної взаємодії, збалансованому підходу до викладання хореографії. Встановлено, що для формування хореографічних навичок у різних стилях танцю в британській дидактиці орієнтуються на теорію конструктивізму, яку інтерпретовано до педагогічної теорії «педагогіка танцювальної нотації» («dance notation pedagogy»), що в поєднанні з таксономією Блума допомагає окреслити мотиви, бажання, інтереси в професійній діяльності загалом та щодо вибраного стилю танцю. Зроблено висновок, що британська система хореографічної освіти ґрунтується на засадах «авторських шкіл», хореографічного аматорства, свободи вибору, свободи творчості й імпровізації, соціального та танцювального лідерства.
Environmental geotechnology for low-grade ore mining with the creation of conditions for the concurrent disposal of mining waste
Authors: Sokolov Igor , Antipin Yuriy , Rozhkov Artem , Solomein Yuriy
Published: March 2023

Due to the constantly deteriorating environmental situation in the regions with mining enterprises, the article considers the topical issue of disposing the maximum possible volume of waste from the mining and processing of low-grade ferrous ores through the creation of an effective underground environmental geotechnology. Traditional procedure with descending mining of reserves with a caving system does not allow waste to be disposed of in a gob. The idea is to use geotechnology based on the ascending order of mining the ore body, room excavation, leaving truncated pillars, and staggered arrangement of adjacent rooms in height, which makes it possible to form containers for waste disposal in the form of a cementless backfill. The main characteristics of the proposed procedure are investigated and compared with the traditional procedure of low-grade iron ores mining. It was established that from the point of view of the complete extraction of reserves and the unit costs for the preparatory-development operations, the processes are comparable, while in terms of the mining quality, the proposed option is much more efficient. Evaluation of environmental geotechnology by the criterion of waste disposal, performed according to the proposed methodology, showed that the combination of these technical solutions ensures the placement in the formed gob from 80 to 140% of all waste generated during the mining and beneficiation of low-grade iron ores.
Final Report: California Tribal Nations Transportation Planning Needs Assessment Study
Authors:   Mineta Transportation Institute, Reddy Seetha , Parker Ashley ,   Mineta Transportation Institute, Reinke David ,   Mineta Transportation Institute, Colligan Kaely ,   Mineta Transportation Institute
Published: March 2023

The Tribal Transportation Planning Needs Assessment Study was a collaborative project conducted by Caltrans and the Mineta Transportation Institute, San Jose State University. The primary goal of the project was to identify the current state of transportation planning activities and partnerships within Tribal governments in California, so that Caltrans can meaningfully engage more actively with Tribal governments early in the planning process and better meet the transportation needs of Tribal communities. The study focused on the 109 federally recognized Tribal Nations in California, and collected data through a survey questionnaire. The key task undertaken by the study team was to engage and support Tribes to ensure that their opinions were heard and to provide as much or as little technical assistance on the questionnaire as they needed. The findings of the study clearly demonstrate that Tribal Nations have challenges related to technical and staff capacity, funding, lack of resources to meet transportation needs, and lack of collaborative partnerships at the local, state and federal levels, among other issues. This study identifies specific needs and provides recommendations for future engagement between Caltrans, local, state and federal agencies with the Tribal Nations.
Determination of Serum Adiponectin Levels in Normal Weight Women with Polycystic Ovary Syndrome
Authors: Hamdi Rana A. , Mohammed Nawar S. , AL-Naddawi Afraa M.
Published: March 2023

Background: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age with primary manifestations of infertility, menstrual dysfunction and clinical or biochemical hyperandrogenism (hirsutism, acne and elevated androgen). Adiponectin is the most abundant adipokine. It has insulin-sensitizing, anti-atherogenic, and antiinflammatory actions.Objective: Low adiponectin levels in women with PCOS have been largely attributed to obesity which is common among these patients. Therefore, the aim of this study was to measure adiponectin levels in normal weight women with PCOS and its contribution to development of disease.Subjects and Methods: Fifty two (52) women were included in this study with age range (21-34 years). Subjects were divided into two groups: group A: twenty seven (27) women with PCOS and group B: twenty five (25) women without PCOS (serve as controls). PCOS can be diagnosed when two of the three following criteria are present (oligoovulation and/or anovulation, clinical and/or biochemical hyperandrogenism and polycystic ovaries as defined by ultrasonography).Results: Mean serum adiponectin level was significantly lower in women with PCOS comparing to those BMI-matched controls (P=0.000).Conclusion:Serum adiponectin levels are not independently determined by the degree of obesity in women but underlying disease may also have some role and this may due to insulin resistance in these patients thus determining serum adiponectin may serve as a useful marker in detecting cases of normal weight women with PCOS.
Congenital pouch colon: A rare presentation of Anorectal malformation
Authors: Mahmood Salah S. , Zain Ahmed Z. , Aboalhab Raghad J.
Published: March 2023

Background: Congenital pouch colon is an usual abnormality associated with anorectal malformation in which the colon is partially or totally replaced by a pouch like dilatation connected to the genitourinary tract by a fistula(colovesical).The condition varies from complete absence of normal colon with the ileum opening into colonic pouch to the presence of nearly normal colon with only the rectum or recto sigmoid being attached to a pouch which in turn connected to bladder by a band or fistula.Objective: is to evaluate the methods of diagnosis and management of(C.P.C) with studying environmental factors especially pesticides and its prevalence.Patients and Methods: A total number of seven cases of(C.P.C) associated with high type of imperforate anus seen in Al-Emamain Al-Kadhemain Medical City and Al-Kadhemia Pediatric Hospital from October 2004 to October 2014.Results: Incidence of (C.P.C) was ( 2.9%) of all cases of high type of imperforate anus with male predominant ( 2.5:1).Most of patients were from Baghdad’s periphery with suspicioun of relationship of pesticides and its prevalence.Preoperative erect abdominal X-ray was diagnostic in (71%) especially type I and II .The most common type of (C.P.C)was type (II) (34%) followed by type (I) (28%). Abdomino-perineal pull-through and anoplasty were performed at mean age sixth month for most patients with resection or tabularizing of the pouch.Fecal continence was( 8o%) .Conclusions: Erect abdominal X-ray have to be done routinely for every case of high type ARM in order not to miss any case of (C.P.C).It is better to excise the pouch completely whatever type was because histopathological exam of the pouch revealed abnormal muscle coat with failure to produce propulsive movement.
Türk Yükseköğretiminde Toplumsal Katkı Kavramının Kapsamı Üzerine
Authors: GÜLEÇ İsmail , DEMİR Seda
Published: March 2023

Üniversitelerin toplumsal katkı açısından misyonları ve içinde bulundukları bölgedeki görevlerinin neler olduğu düşünülürse bir parçası olduğu topluma akademik katkılardan sonra sosyal, ekonomik ve beşerî-etik, etnik çeşitlilik, hümanizm vs. gibi- bazı açılardan katkı sağlamaları beklenir. Mezunlarının ileride bir parçası olacakları toplumu daha yakından tanımaları ve üniversitenin tüzel bir kişilik olarak toplumda bıraktığı izlenim ve etki, kurumun toplumdaki paydaşları ve uygulama alanları ile olan ilişkisini sağlam tutmasını sağlamakla kalmayacak aynı zamanda kabul edeceği öğrenci kitlesi ve akademisyen camiasının kalite ve etkililik seviyesini de artıracaktır. Başka bir ifade ile üniversitenin topluma maddi-manevi anlamda sağladığı katkı, bu durumun kurum adına bir “kazan-kazan” ilişkisine dönüşmesini sağlayabilir. Çalışmada, üniversitelerin “kurumsal sosyal sorumluluğu” kavramının üniversite-toplum ilişkisi ve paydaşları açısından nasıl bir önem arz ettiği, dünya genelinde bu iki unsurun sosyal sorumluluk tabanında nasıl birleştiği ve bu durumun Türkiye’deki tabloda nasıl seyrettiği gibi konulara değinilerek uygulamaya yönelik birkaç noktanın altı çizilecektir. Çalışmanın üniversitelerin kurumsal sorumluluğu ve toplum iş birliği açısından alandaki sayılı çalışmalara ek olarak global bir panorama çizmek ve Türk üniversiteleri açısından toplumsal katkı sağlamaya yönelik uygulamaların nasıl genişletilebileceğini vurgulamak adına alan yazına katkı sağlaması hedeflenmektedir.
Fârâbî’nin Tümevarım Anlayışı Üzerine Bir İnceleme
Authors: AKBAY Yunus Emre
Published: March 2023

Bu makalede Fârâbî’nin tümevarım anlayışı tümevarımın tanım, kullanım amacı, beş sanattaki yeri, eğitim ve öğretimdeki işleviyle incelenmektedir. Çalışmanın iddiası, Fârâbî’nin tümevarımın doğasından kaynaklanan bazı problemlere cevap verebilecek şekilde kendi mantık anlayışına özgü olarak tümevarımı yorumladığıdır. Fârâbî’nin eserlerinin öncelendiği araştırmada metin analizi ve ikincil literatürdeki eserlerle yapılan karşılaştırmalardan faydalanılmıştır. Filozofa göre tümevarım, parçadan bütüne yönelik bir akıl yürütmedir. O, tümevarımı burhân sanatında tümel önermenin anlaşılması; cedeldeyse külli öncülün tasdiklenmesi açısından yorumlar. Fârâbî, salt tümevarımı bir ispat yöntemi olarak görmeyerek, Aristoteles’in burhân teorisindeki tümevarımın rolünü değiştirir. Ayrıca o, tümel kavram, önerme ve bilimin ilk ilkelerini tümevarımın maksatları arasında sayan Aristoteles yorumundan farklı bir öneri sunar. Filozof tekillerdeki ortak özelliklerin verili olmadan tümevarımla bilinemeyeceği, tümevarımın döngüsel olduğu ve tekillerin tümevarımla tüketilemeyeceği iddialarına cevap verir. Fârâbî, Aristoteles’te açıktan yapılmayan tam ve eksik tümevarım ayrımını yaparak tam ve eksik tümevarımın burhânî ya da cedelî akıl yürütmelerdeki kullanımıyla ortaya çıkan yargının kesinliğini tartışır. Fârâbî, tümevarımı, temsil ve tümdengelimle birlikte karmaşık argüman kurgulamak üzere kullanır. O, tümevarımın eğitim açısından faydalarını sayarak meseleyi bu boyutuyla analiz eder. Bununla beraber, farklı ifadeleri ışığında tecrübe ve tümevarımın nasıl bir ilişkiye sahip olduğu Fârâbî’nin eleştirilebilecek yönleri arasında sayılabilir. Sonuç olarak Fârâbî’nin tümevarıma dair bazı şârihlerin ışığında fakat kendi felsefesine uygun alternatif bir okumayı önerdiği söylenebilir.
Identifying the source of peritoneal carcinomatosis by molecular biological method (a clinical case)
Authors:   Bashkir State Medical University, Ufa, Russian Federation, Ishmuratova K.R. ,   Republican Clinical Oncological Dispensary, Ufa, Russian Federation
Published: March 2023

In recent decades, multiple biological markers have been discovered which demonstrate a high specificity in determining tumor phenotypes. There has been much debate on their role in differentiating the origin of metastasis. This article presents a clinical case of peritoneal carcinomatosis arising from breast carcinoma. The immunohistochemical method was used to determine the tumor phenotype. For this purpose, the markers of gastrointestinal, ovary and breast tumors were utilized, including CDX2, PAX 8, WT1, CK7, CK20, Mammaglobin, and GCDFP-15. The findings of molecular biological phenotyping confirmed the diagnosis of primary multiple malignant neoplasms with peritoneal carcinomatosis arising from breast carcinoma. More accurate identification of tumor phenotypes plays an important role in predicting the disease outcome and specifying indications for prescribing anticancer drug treatments. The described clinical case demonstrates that molecular biological phenotyping can be used as a proving method for identifying the origin of peritoneal carcinomatosis. The development of a panel of markers for different tumor localizations will allow a reliable detection of the source of peritoneal carcinomatosis. In cases of diagnosing peritoneal carcinomatosis from tumors with an undetected primary lesion, such panel of biological markers will help to reduce the time of examination and improve the quality of medical care. KEYWORDS: peritoneal carcinomatosis, diagnosis, biological markers, immunohistochemistry, breast cancer, ovarian cancer, colorectal cancer, gastric cancer. FOR CITATION: Ishmuratova K.R. Identifying the source of peritoneal carcinomatosis by molecular biological method (a clinical case). Russian Journal of Woman and Child Health. 2023;6(1):31–33 (in Russ.). DOI: 10.32364/2618-8430-2023-6-1-31-33.
New ore-magmatic ring-type structure in the Muzkol-Rangkul anticlinorium, Central Pamir
Authors: Litvinenko A. K. , Odinaev Sh. A.
Published: March 2023

Background. The minerogenic specialization of the Muzkol-Rangkul anticlinorium consists in industrial gemstone deposits of ruby, cordierite, almandine, aquamarine, topaz, tourmaline, scapolite, etc. Large ore objects in this area are unknown. Until recently, the area has had a negative assessment in terms of rare, rare earth, and noble metals.

Aim. To justify the identification of a previously unknown magnetic ring-type structure and to study the associated ore geochemical anomalies.

Materials and methods. Rock and mineral samples collected at the Chernogorskoye deposit in 2016 and 2018 were examined. The mineral composition were determined using a Polam-R211 petrographic microscope and confirmed by XRD analysis using a DRON-3M diffractometer (analyst A.V. Fedorov, Sergo Russian State University for Geological Prospecting). The chemical composition of mineral samples was studied by X-ray microanalysis using a Cameca SX 100 instrument (analyst N.N. Kononkova, Vernadsky Institute of Geochemistry and Analytical Chemistry). The chemical compositions of rock samples was determined using an X-ray fluorescence spectrometer AXIOS Advanced (analyst T.G. Kuzminа, Vernadsky Institute of Geochemistry and Analytical Chemistry).

Results. A ring-type intrusion composed of hornblende peridotites, hornblendites, and gabbroids was identified in the Muzkol-Rangkul anticlinorium, in the area of the Chernogorskoye gem scapolite deposit. The gabbroids here contact the metamorphic rocks of the Sarydzhilga formation along the ring fault. The geochemical anomalies of Co, Ni, W, Nb, Ti, and REE were revealed in the contour of the ring structure and along its periphery.

Conclusion. The ring-type intrusion identified by the authors is a source of geochemical anomalies.