bluuebunny/crossref_metadata_2025 huggingface dataset:
Developmental biology of amphibians after Hans Spemann in Germany.
Authors: Grunz H
Published: February 2025

After the Hans Spemann and Hilde Mangold discovery of the importance of the dorsal blastopore lip for axis formation in the early embryo (Nobelprize for Spemann, 1935), the scientific community tried in a goldrush-like manner to find the inducing factors responsible for the programming of early embyronic determination and differentiation. The slow progress towards a solution of this problem caused a fading of interest on behalf of most laboratories. This article describes the activities of a few laboratories in Finland, Japan and Germany, which continued their studies despite tremendous experimental difficulties. Finally only Heinz Tiedemann's group in Berlin was the first which could isolate a mesoderm/endoderm inducing factor in highly purified form, the so-called vegetalizing factor, now known as activin. Furthermore this article describes the identification of neuralizing factors like Chordin, Cerberus and Dickkopf in the zone of the Spemann-Mangold organizer. The finding that BMP-4 acts as an antagonist to these factors located on the dorsal side led to a new understanding of the mechanisms of action of inducing (neuralizing) factors and early embryonic pattern formation. Moreover, the observations that closely related genes and their products were also found in Drosophila, Zebrafish, Mice and Human were the basis for new concepts of evolutionary mechanisms (dorsal/ventral and anterior/posterior polarity or conserved processes in eye-development of all 7 animal phyla).
From the spectrin gene to the assembly of the membrane skeleton.
Authors: Wasenius V M , Saraste M , Lehto V P
Published: February 2025

The complete nucleotide sequence coding for the chicken brain alpha-spectrin was determined. It comprises the entire coding frame, 5'- and 3'-untranslated sequences terminating in a poly(A)-tail. The deduced amino acid sequence shows that the alpha-chain contains 22 segments, 20 of which correspond to the typical 106 residue repeat of the human erythrocyte spectrin. Some segments non-homologous to the repeat structure reside in the middle and COOH-terminal regions. Sequence comparisons with other proteins show that these segments evidently harbour some structural and functional features such as: homology to alpha-actinin and dystrophin, two typical EF-hand structures (calcium-binding) and a putative calmodulin-binding site in the COOH-terminus and a sequence homologous to various src-tyrosine kinases and to phospholipase C in the middle of the molecule. Comparison of our sequence with other partial alpha-spectrin sequences shows that alpha-spectrin is well conserved in different species and that the human erythrocyte alpha-spectrin is divergent.
Factors responsible for the establishment of the body plan in the amphibian embryo.
Authors: Grunz H
Published: February 2025

A central topic of embryology is the establishment of the body plan during embryogenesis. Starting with maternal factors distributed in the early cleavage stages in distinct patterns and gradients cell-to-cell interactions including early embryonic induction result in the formation of mesoderm and the organizer area. While many facts are known about the role of growth factors like activin (closely related to the vegetalizing factor), processed Vg1, BMPs and FGF for mesoderm formation, the establishment of the central nervous system is not yet well understood. However, there is growing evidence that neural induction is a multistep process at the level of the dorsal mesoderm (organizer) and the reacting neuroectoderm. Therefore the existence of only one neuralizing factor is unlikely. We report about data that follistatin protein is not a direct neural inducer. Furthermore our comparative studies of Xenopus and Triturus exogastrulae indicate that planar signals are unlikely in the Triturus embryo (urodeles) during the early steps of neural induction. Vertical signals emanating from the chordamesoderm are essential for the terminal neuralization and regionalization of the central nervous system during gastrulation for both Xenopus and Triturus. The putative role of neuralizing factors and BMP/activin-like molecules for the stabilization or shift of neuroectoderm into different pathways of differentiation (epidermis or neural default state) is discussed.
The formation of somite compartments in the avian embryo.
Authors: Brand-Saberi B , Wilting J , Ebensperger C , Christ B
Published: February 2025

The somites develop from the unsegmented paraxial mesoderm that flanks the neural tube. They form in an intrinsic process which lays down the primary segmental pattern of the vertebrate body. We review the processes of somitogenesis and somite differentiation as well as the mechanisms involved in these developmental events. Long before overt differentiation occurs, different compartments of the still epithelial somites give rise to special cell lines and to particular derivatives. By means of isotypic grafting between quail and chick embryos, it is possible to follow the fate of groups of somitic cells. In this way, the development of the myotome and the back dermis from the dorsomedial quadrant and of the hypaxial body wall and limb musculature from the dorsolateral quadrant was established. The two ventral quadrants and the somitocoele give rise to the chondrogenic/fibroblastic lineage of the sclerotome and form the vertebral column. Somite compartments can first be visualized by the expression pattern of Pax genes. Pax-3 is expressed in the dorsal part of the epithelial somite, while the ventral two thirds express Pax-1, a marker of sclerotome development. Pax-3 expression is retained also in the premitotic myogenic cells that migrate into the limb buds. In differentiating myoblasts, Pax-3 expression is turned down and taken over by the activation of MDF's. This initial event in myogenesis occurs in the absence of local signals, whereas the expression of Pax-1 in the sclerotome can be shown to be induced by signals from the notochord and floor-plate of the neural tube. Epaxial myotome differentiation is supported by the neural tube, after the neural tube has received patterning signals from the notochord. The hypaxial musculature and limb musculature differentiate independently of the axial structures. The myogenic cells migrating within the limb buds respond to signals of the lateral plate mesoderm which guide their distalward migration and pattern the muscle.
Historical and current perspectives on Japanese encephalitis in Sulawesi, Indonesia
Authors: Rahma Nur , Nuradji Harimurti , Dharmayanti NLP Indi , Sendow Indrawati , Adji Rahmat Setya , Saepulloh Muharam , Rusdiyah Rusdiyah , Wahid Isra
Published: February 2025

Japanese encephalitis (JE), a mosquito-borne viral disease, poses significant public health risks in endemic regions, such as Indonesia. Sulawesi, one of the archipelago’s largest islands, presents a high potential for JE transmission due to its conducive environmental, economic, and cultural factors. Between 1972 and 2017, JE-positive samples were detected sporadically in various hosts, including humans, pigs, bats, cattle, goats, chickens, and mosquitoes (Culex tritaeniorhynchus). This review consolidates historical data and provides a contemporary perspective on JE ecology in Sulawesi. The island’s extensive rice fields (95% of districts) and its high density of amplifying hosts – especially pigs, which inhabit 65.5% of districts – highlight critical transmission dynamics. In addition, Sulawesi supports a diverse array of reservoir hosts, such as endemic bats and bird species, which enhance JE’s zoonotic potential. Bats, including Dobsonia viridis and Rousettus celebensis, are particularly notable for their reservoir roles. Furthermore, at least nine mosquito vector species, led by C. tritaeniorhynchus, thrive in Sulawesi’s wetland ecosystems, amplifying transmission risk. Despite the island’s high-risk profile, JE surveillance remains inconsistent, with limited government-led diagnostic programs. Historical and recent data underscore the need for systematic investigations into JE’s epidemiology, emphasizing molecular and serological detection, vector surveillance, and the role of amplifying hosts in transmission cycles. Key challenges include limited awareness, diagnostic infrastructure, and climate change, which exacerbate vector bionomics and disease dynamics. This review advocates for the integration of JE diagnostic tools, public health interventions, and vaccination programs tailored to Sulawesi’s ecological and sociocultural context. These measures are essential to mitigate JE transmission and protect both human and animal health.

Keywords: amplifying hosts, epidemiology, Japanese encephalitis, Sulawesi, vectors, zoonotic reservoirs.
Effects of adding dietary bakery waste to corn on broiler growth performance, carcass traits, and feed costs
Authors: Sirirotjanaput Wilaiwan , Chobtang Jeerasak , Isuwan Auraiwan , Chimtomg Supawadee , Sittiya Janjira
Published: February 2025

Background and Aim: The rising cost of corn in livestock feed has driven interest in alternative feed ingredients. Bakery waste, a byproduct of bakery production, presents a viable substitute for corn in broiler diets. This study evaluated the effects of replacing 40% of dietary corn with bakery waste on broiler growth performance, carcass traits, and feed costs. We hypothesized that this substitution would maintain performance while reducing feed costs.

Materials and Methods: A total of 240 1-day-old Ross 308 broiler chicks were randomly assigned to two dietary treatments: (T1) A control diet with 100% corn and (T2) a diet replacing 40% of corn with bakery waste. Each group had six replicates of 20 birds, housed under identical conditions with ad libitum access to feed and water for 35 days. Growth performance (feed intake [FI], body weight gain [BWG], and feed conversion ratio [FCR]) was assessed at different growth stages. Carcass traits were evaluated in selected birds, and feed cost per kilogram gain (FCG) was calculated. Statistical analysis was performed using a paired Student’s t-test, with significance set at p < 0.05.

Results: No significant differences were observed in FI, BWG, or FCR between groups across all growth phases (p > 0.05). However, FCG was significantly lower in the T2 group compared to T1 (p < 0.05), indicating reduced feed costs. Carcass traits showed no major differences except for significantly lower eviscerated carcass yield and breast yield in the T2 group (p < 0.05).

Conclusion: Replacing 40% of corn with bakery waste in broiler diets is a cost-effective strategy without adverse effects on growth performance. However, the reduction in breast yield suggests potential amino acid imbalances, warranting further investigation into nutrient digestibility and fat deposition. Future research should optimize bakery waste inclusion levels to ensure economic feasibility while maintaining meat quality.

Keywords: alternative feedstuffs, broiler diets, broiler performance, corn, feed cost.
Ciências e Saberes do Campo: a contribuição e o aproveitamento dos saberes científicos e populares no desenvolvimento das atividades relacionadas à Agroecologia
Authors: Silva José Carlos Marinho da , Rossetto Onélia Carmem
Published: February 2025

Oportunizar conhecimentos e saberes tradicionais, possibilita que práticas realizadas por nossos antepassados, não se percam mediante as grandes transformações da sociedade e do mundo globalizado. A disciplina implantada nas escolas do/no campo no estado de Mato Grosso, intitulada com “Ciência e Saberes do Campo”, tem por objetivo contribuir para a promoção vivências, discussão de valores e práticas camponesas realizadas na zona rural, durante anos, através de saberes populares. São realizadas durante as aulas de ciência e saberes do campo, produção agroecológica, economia solidária e técnicas orgânicas de produção e cultivo.
Sebaran Makroplastik di Kawasan Ekowisata Mangrove Karangsong Indramayu Jawa Barat
Authors: Wijdanisa Rahma , Arief Mochamad Candra Wirawan , Nurruhwati Isni , Ismail Mochamad Rudyansyah
Published: February 2025

Sampah plastik banyak dijumpai di berbagai wilayah pesisir, terbawa oleh gelombang arus dan pasang surut, serta kontribusi aktivitas daratan melalui sungai yang bermuara di laut. Ekosistem pesisir yang saat ini mengalami dampak peningkatan sampah plastik antara lain terumbu karang, padang lamun, pantai dan ekosistem mangrove. Ekosistem mangrove menjadi wilayah dengan ancaman akumulasi sampah makroplastik dengan jumlah sangat banyak dari berbagai aktivitas. Kawasan mangrove Karangsong di Kabupaten Indramayu merupakan ekosistem mangrove yang memiliki fungsi dan dikelola sebagai kawasan ekowisata. Riset ini bertujuan untuk mengetahui komposisi jenis dan kepadatan makroplastik di kawasan ekowisata Mangrove Karangsong. Penelitian menggunakan metode survei dengan plot transek 10 x 10 m2 secara stratified random sampling. Hasil penelitian ini menunjukkan makroplastik terbanyak merupakan jenis Polyethylene Terephthalate (PETE) sebesar 33,47% dengan kepadatan 5,43 potong/m2, sementara makroplastik paling sedikit dijumpai pada jenis Polyvinyl Chloride (PVC) sebesar 0,15% dengan kepadatan 0,01 potong/m2. Sebaran sampah makroplastik yang ditemukan umumnya terkumpul tersangkut pada sistem perakaran mangrove dan tertutup substrat sedimen. Jenis makroplastik yang ditemukan, mengindikasikan pentingnya pengelolaan sampah di kawasan ekowisata maupun dari sumber utama penghasil.
Justification of a price range for topical antifungal drugs based on patient preferences
Authors: Tkachenko N. O. , Bushuieva I. V. , Prytula R. L. , Parchenko V. V. , Shmatenko O. P.
Published: February 2025

The price factor is an important element when using a therapy management, that is complicated by the deterioration in the socio-economic situation of Ukrainians and the National Health Care system in the middle of war.
The aim is to examine patients’ willingness-to-pay for topical antifungal drugs (TAFDs) taking into account their differing consumer characteristics in order to justify the economic component in the development and pharmaceutical market introduction of national drugs and to formulate recommendations for improving the level of pharmaceutical care for patients with fungal skin diseases.
Materials and methods. The results of a sociological TAFDs’ consumer survey were used as the basic study material. In this study, the methods of information retrieval, summarizing, formalizing, questioning, van Westendorp’s Price Sensitivity Meter (PSM) were used. The respondent geography covered the Zaporizhzhia, Dnipropetrovsk, Cherkasy, Poltava, Ivano-Frankivsk, Kyiv, Odesa regions.
Results. A total group analysis of price sensitivity was conducted including 8 TAFDs with calculation of optimal (OPP), indifferent (IDP), minimum (MCP) and maximum (MEP) respondents’ willingness-to-pay prices. The same prices were subsequently calculated in the intra-group price analysis of respondents with different income levels and experience in drug therapy for fungal skin diseases. The cumulative distribution of respondents was graphed at three stages of the study calculations for the identified subgroups (64 graphs in total).
Conclusions. The van Westendorp’s Price Sensitivity Meter (PSM) has been used to examine patients’ willingness-to-pay for topical antifungal drugs considering their different consumer characteristics: final dosage form – gel, ointment, cream, solution, spray; combined / monocomponent. At the same time, opinion of patients with different levels of income and experience of drug therapy for fungal skin diseases has been sought. Based on the studies, the economic component and the promising form of a new antifungal drug for topical use (pharmacy or industrial production) – a spray or gel with a price in the range of UAH 181–230 have been justified.
Using one-dimensional thinned antenna arrays to form a two-dimensional MIMO antenna array
Authors: Stepanov Maksim , Artyushenko Vadim , Sokolov Vadim , Podkopayev Artemy
Published: February 2025

The issue of synthesizing a two-dimensional thinned virtual aperture multiple input-multiple output (MIMO) antenna array based on one-dimensional thinned linear antenna arrays is considered. The receiving and transmitting elements of the MIMO antenna array are located on two orthogonal lines. They are corresponding to a linear antenna array of appropriate length. These linear antenna arrays are thinned out by a genetic algorithm. To form a thinned virtual aperture of a MIMO antenna array, the location of its receiving and transmitting elements corresponds to the location of the elements of the thinned antenna arrays. It is shown that the directivity multiplier of the thinned virtual aperture of a MIMO antenna array has lower side lobes than the full aperture. The dependence of the level of the maximum side lobe on the thinning coefficient of the virtual aperture of the MIMO antenna array is given.
The crystal structure of benzyl 2,2,5,5-tetramethylthiazolidine-4-carboxylate, C15H21NO2S
Authors: Shao Lingli , Cai Shuping , Li Zhiming , Feng Yutao , Chen Mengting , Xu Kaining , Liu Zhenxiang
Published: February 2025

C15H21NO2S, monoclinic, P21/n (no. 62), a = 12.0769(6) Å, b = 6.1507(3) Å, c = 20.4335(11) Å, β = 90.710(2)°, V = 1517.71(13) Å3, Z = 4, T = 170 K, R
gt(F) = 0.0341, wR(F
2) = 0.0376.
Fermi motion in nucleons and the generalized Heisenberg uncertainty relation
Authors: Kholmetskii Alexander , Missevitch Oleg , Yarman Tolga
Published: February 2025

In a series of our papers (e.g., A.L. Kholmetskii, et al. Ann. Phys. 392, 49 (2018)) we proposed to redefine the momentum operator for an electrically charged quantum particle in an electromagnetic (EM) field through the sum of its mechanical momentum (
P

M
) and the interactional electromagnetic momentum (
P

EM
), instead of the standard definition of this operator, associated with the canonical momentum of the particle. In the present contribution, we represent our three-step way to the new momentum operator and focus on one of its principal implications, named the “generalized Heisenberg uncertainty relation”, where, in comparison to its standard form, the mechanical momentum of a charged particle
P

M
is replaced by the sum of
P

M
and
P

EM
. We then apply the generalized uncertainty relation to the analysis of the Fermi motion of quarks in the proton and neutron and show that a quark with a unique charge (i.e., the d-antiquark in the proton and the u-antiquark in the neutron) should have a more narrow momentum distribution compared to the wider momentum distribution of the remaining quarks (the two u-quarks in the proton and the two d-quarks in the neutron) in their Fermi motion. The agreement of these results with the available experimental data does not touch the validity of the results of calculation of quantum chromodynamics (QCD) regarding the description of the proton and neutron, but rather enriches their physical interpretation.
Kompetencije odgojitelja za provedbu potpomognute komunikacije
Authors: Kovačević Sonja , Barbir Joško , Bodrožić Anita
Published: February 2025

Povećanje svjesnosti o važnosti prepoznavanja obilježja razvojnih teškoća djece te važnosti rane intervencije i pravovremenoga pružanja primjerene podrške rezultiralo je boljom kvalitetom života djece s teškoćama u razvoju. U prošlosti su djeca s teškoćama u razvoju bila izolirana i etiketirana zbog svojih različitosti te su oni bili ti koji su se trebali prilagođavati društvu. Napretkom znanosti i osvješćivanjem društva o različitostima sve se više teži provođenju inkluzivnoga pristupa i nastojanju da svaki pojedinac, bez obzira na svoje razvojne specifičnosti, ima jednaka prava na maksimalno ostvarivanje svojih potencijala u skladu s osobnim mogućnostima. Danas je velika odgovornost stavljena na socijalnu okolinu koja treba pružiti primjerenu razinu podrške kako bi djeca s teškoćama u razvoju mogla prevladati različite prepreke koje proizlaze iz njihovih razvojnih specifičnosti, a sprječavaju ih u ravnopravnu i učinkovitu sudjelovanju u društvu. Ako se pronađe odgovarajući komunikacijski kanal djetetu s teškoćama u razvoju, pružamo mu mogućnost za ostvarivanje socijalnih interakcija, učenje, stjecanje iskustava i u konačnici pružanje vlastita doprinosa društvu. Motiviranost i osposobljenost odgojitelja za primjenu potpomognute komunikacije, inkluzivni pristup te kontinuirano usavršavanje imaju važnu ulogu u stvaranju optimalnih uvjeta te pružanju kvalitetne i pravovremene pomoći i podrške djetetu s teškoćama u razvoju. Cilj je ovoga rada bio istražiti mišljenja odgojitelja o njihovoj spremnosti i kompetentnosti za rad s djecom s teškoćama u razvoju, vještinama primjene potpomognute komunikacije u svakodnevnim aktivnostima te ulozi stručnoga tima i ustanove u pružanju pomoći i podrške djeci s teškoćama u razvoju kako bi se stvorili optimalni inkluzivni uvjeti. Dobiveni su rezultati pokazali da su odgojitelji svjesni svih teškoća s kojima se susreću u praksi pri provođenju kvalitetne inkluzije. Najčešći su izazovi s kojima se odgojitelji susreću nedovoljna educiranost u području rada s djecom s poteškoćama u razvoju, nedostatak podrške stručnoga tima, uvjeti u kojima rade (velik broj djece) i slično.
УЛУЧШЕНИЕ ВОСПЛАМЕНЯЕМОСТИ И РЕАКЦИОННОЙ СПОСОБНОСТИ БОРА ЗА СЧЕТ МОДИФИКАЦИИ ПОВЕРХНОСТИ
Authors: LIU  J. , WANG  D. Q. , ZHANG  Z , LI  F. S.
Published: February 2025

Бор является одним из наиболее ценных компонентов ракетного топлива. Однако высокая температура кипения оксида бора (B2O3) на его поверхности (1 860 °C) затрудняет контакт между активным бором и окислителем в ходе процессов горения и воспламенения. В результате энергия воспламенения бора оказывается выше, а скорость горения — ниже. Для повышения эффективности воспламенения, а также реакционной способности бора его поверхность была модифицирована путем очистки растворителем, наращивания поверхности, а также изготовления его композита с алюминием, имеющим высокую температуру кипения. Композитные частицы, состоящие из бора, очищенного при помощи этанола, и толстых хлопьев алюминия, обозначаемые EB/TF-Al, продемонстрировали наилучшую реакционную способность, на 96.6 % большую в сравнении с композитными частицами, состоящими из чистого бора и толстых хлопьев алюминия (RB/TF-Al). Композитные частицы, состоящие из бора с наращенной поверхностью и толстых хлопьев алюминия (KHB-3/TF-Al), имеют минимальную энергию воспламенения, на 29.1 % ниже в сравнении с чистым бором. Поскольку модификация поверхности бора приводит к улучшению воспламеняемости, а также к увеличению его реакционной способности, ожидается, что такой подход позволит улучшить характеристики ракетного топлива на основе бора.

Boron is one of the most valuable fuels for rocket propellants. However, the boron oxide (B2O3) on the B surface has a high boiling point (1860 °C), which hinders the contact between the internal active B and the oxidation component during the ignition and combustion process. As a result, the ignition energy of B is higher and the combustion reaction rate is lower. In order to improve the ignition performance and reaction rate of B, a surface modification of B by means of surface purification by a solvent, surface grafting, and making a composite with aluminum (Al), which has a high combustion temperature, has been prepared. Composite particles of B purified by ethanol and thick flake Al (TF-Al), denoted by EB/TF-Al, have the fastest reaction rate higher by 96.6% than that of raw B and TF-Al composite particles (RB/TF-Al). Surface grafting of B with TF-Al composite particles (KHB-3/TF-Al) ensure the minimum ignition energy, which is 29.1% lower than that of raw B. As the ignition performance and reaction rate of B are improved by means of surface modification, the performance of B-based rocket propellants is expected to be improved.
РАВНОВЕСНЫЙ СОСТАВ ПРОДУКТОВ В РЕАКЦИОННОЙ СИСТЕМЕ ДИОКСИД ГАФНИЯ – КАЛЬЦИЙ – АЗОТ – УГЛЕРОД ПРИ АДИАБАТИЧЕСКОЙ ТЕМПЕРАТУРЕ ГОРЕНИЯ
Authors: АВРАМЧИК А.Н. , БРАВЕРМАН Б.Ш.
Published: February 2025

Представлены результаты термодинамического расчета адиабатической температуры и равновесного состава продуктов восстановления HfO2 кальцием в зависимости от содержания углерода и кальция при различном давлении. В расчетах задавалась возможность формирования твердых растворов HfN—HfC, образование которых отожествлялось с образованием карбонитрида гафния. Показано, что значения адиабатической температуры находятся в диапазоне 2 000 ÷ 2 900 К, и ее повышение ограничено плавлением CaO при 2 900 К. Введение углерода, как правило, понижает адиабатическую температуру, а рост давления приводит к её росту. Выявлена связь между составом продуктов и видом температурных кривых. Основной причиной роста адиабатической температуры с ростом давления, является смещение равновесий в сторону образования конденсированных фаз и увеличение доли HfN в продуктах.

This paper presents the results of thermodynamic calculation of adiabatic temperature and the equilibrium composition of products of HfO2 reduction with calcium depending on carbon and calcium content at different pressures. The calculations are based on the possibility that solid HfN–HfC solutions could be formed, and their formation is identified with that of hafnium carbonitride. It is shown that adiabatic temperatures lie in a range of 2000–2900 K, and its elevation is limited by the melting of CaO at 2900 K. The introduction of carbon often reduces the adiabatic temperature, and a pressure rise leads to its increase. A connection is revealed between the composition of products and the type of temperature curves. The main reason why adiabatic temperature rises along with pressure is a displacement of equilibrium toward the formation of condensed phases and an increase in the HfN proportion in the products.
САМОРАСПРОСТРАНЯЮЩИЙСЯ ВЫСОКОТЕМПЕРАТУРНЫЙ СИНТЕЗ В ДВУХСЛОЙНЫХ ПОРОШКОВЫХ СМЕСЯХ (NI + AL)/(PBO2 + B + AL2O3 + СТЕКЛО)
Authors: ШУЛЬПЕКОВ  А. М. , ГАББАСОВ  Р. М. , ЛЕПАКОВА  О. К. , АФАНАСЬЕВ  Н. И.
Published: February 2025

Широкое распространение плоских электронагревателей в технике и бытовых приборах требует поиска более простых и дешевых технологий их получения. В данной работе предложен способ получения электропроводящего покрытия (NiAl) и электроизоляционного слоя (стеклокерамика) в одну стадию — методом самораспространяющегося высокотемпературного синтеза (СВС) в термически сопряженной порошковой системе (Ni + Al)/(PbO2 + B + Al2O3 + стекло). Исследован процесс распространения фронта волны горения, изучено влияние толщины слоев, соотношения компонентов в порошковой смеси PbO2+ B + Al2O3 + стекло на скорость распространения и температуру фронта волны горения. Обнаружено расширение фронта волны экзотермического процесса при добавлении смеси PbO2+ B в нижний слой. Добавление этой смеси позволяет снизить толщину слоя NiAl и обеспечить формирование однородного диэлектрического покрытия. Изучены фазовый состав и микроструктура покрытия. Установлены оптимальные соотношения толщин слоев и состава порошковой смеси слоев. Показана принципиальная возможность формирования электропроводящего и диэлектрического покрытия методом самораспространяющегося высокотемпературного синтеза в одну стадию.

The widespread use of flat electric heaters in technology and household appliances requires the search for simpler and cheaper technologies for their production. This work proposes a method for producing an electrically conductive coating (NiAl) and an electrically insulating layer (glass ceramics) in one stage – by the method of self-propagating high-temperature synthesis (SHS) in a thermally conjugated powder system (Ni + Al)/(PbO2 + B + Al2O3 + glass). The process of propagation of the combustion wave front has been studied, the influence of layer thickness, the ratio of components in the powder mixture PbO2+ B + Al2O3 + glass on the propagation speed and temperature of the wave front has been studied. combustion. An expansion of the wave front of the exothermic process was discovered when a mixture of PbO2 + B was added to the lower layer. The addition of this mixture makes it possible to reduce the thickness of the NiAl layer and ensure the formation of a uniform dielectric coating. The phase composition and microstructure of the coating were studied. The optimal ratios of layer thicknesses and the composition of the powder mixture of layers have been established. The fundamental possibility of forming an electrically conductive and dielectric coating by the method of self-propagating high-temperature synthesis in one stage is shown.
Influencia del engagement en la satisfacción laboral de los trabajadores de una empresa metalmecánica de Lima, Perú
Authors: Castañeda Flores Amalia Rosario , Shigyo Ortiz Carlos Augusto , Cevallos Ampuero Juan Manuel , Flores Gutiérrez José Ovidio
Published: February 2025

La gerencia de las empresas debe priorizar la salud ocupacional para lograr altos niveles de desempeño. El objetivo de este estudio fue evaluar la influencia del engagement en la satisfacción laboral de los trabajadores de una empresa metalmecánica ubicada en Lima, Perú. Para la recolección de datos, se utilizaron la escala Utrecht Work Engagement Scale (UWES-9) y el cuestionario de Satisfacción Laboral S10/12; adicionalmente, se recabó información sobre variables sociolaborales. Se aplicó un diseño no experimental de tipo transversal con alcance explicativo y enfoque cuantitativo a una muestra censal de 74 trabajadores. Se empleó además un modelo PLS-SEM. Los resultados evidencian tres conclusiones: 1) la escala UWES-9 demuestra fiabilidad y validez al medir el constructo engagement en el sector metalmecánico, 2) la escala S10/12 demuestra fiabilidad y validez al medir el constructo satisfacción laboral en el sector metalmecánico y 3) el engagement influye positiva y significativamente en la satisfacción laboral de los trabajadores de empresas metalmecánicas.
Transformación digital y bancarización de clientes en una institución financiera en el distrito de San Isidro (Lima, Perú), 2022
Authors: Huachaca Urbina Antonio Roberto , Cumpa Vila Luis Antonio
Published: February 2025

La transformación digital supone una gran oportunidad para la bancarización, pues genera un incremento en la productividad y la competitividad de los profesionales. El propósito de este estudio de investigación fue determinar la relación entre las variables transformación digital y bancarización de clientes en una institución financiera localizada en la zona de San Isidro (Lima, Perú) en el año 2022. Para tal fin, se empleó un enfoque cuantitativo y un diseño de investigación no experimental y transversal con alcance correlacional. Asimismo, la encuesta fue empleada como técnica y el cuestionario como herramienta, ambos fueron aplicaron a toda la población de la institución financiera investigada, la cual estuvo conformada por 40 empleados (muestra censal). El análisis de la hipótesis general reveló una correlación (r = 0.564), lo que sugiere una relación moderada entre las variables. Por lo tanto, se concluye que existe una correlación significativa entre la transformación digital y el uso bancario.
Innovación tecnológica Kipa en procesos de teñido de algodón reactivo alineados con las ODS en la empresa, para la producción de prendas artesanales
Authors: Cachay Anardo Adriana Edith , Bellin Cier Renato , Lupis Davila Pablo José
Published: February 2025

En la actualidad, el uso del pigmento reactante en el teñido de fibras textiles está muy extendido. Esto se debe a las propiedades de resistencia que la reacción covalente producida entre el colorante y la fibra le confiere a esta última después del proceso de teñido. Sin embargo, para alcanzar el nivel de solidez requerido, es necesario suprimir el colorante hidrolizado mediante múltiples enjuagues, por lo que se produce un alto consumo de agua, tiempo y energía. Dada la importancia de preservar los recursos de la naturaleza, especialmente el agua, que es un elemento clave en el proceso teñido, es crucial identificar periodos significativos en los que se pueda minimizar su consumo. Es en las fases subsiguientes al teñido (jabonado y enjuagues) en donde se produce el mayor desperdicio de este recurso potable, pues en ellas se consume el 70% del agua utilizada en el proceso de teñido con pigmento reactante. El objetivo de esta investigación consiste en optimizar el teñido de algodón mediante un proceso denominado «Kipa», con la finalidad de reducir el consumo de recursos, tales como el agua, y minimizar el uso de elementos tóxicos en el proceso de teñido, tales como el cloruro de sodio y los químicos auxiliares. Asimismo, se busca identificar características temporales y térmicas, como el pH y la afinidad de baño, y el costo de los productos utilizados con la finalidad de optimizar el proceso de teñido.
Modelo de gestión basado en el mantenimiento productivo total (TPM) y Six Sigma para aumentar la efectividad global de los equipos (OEE) en una empresa de confecciones de Lima, Perú
Authors: Ortiz Porras Jorge Enrique , Bancovich Erquínigo Andrei Mijailo , Quintana Saavedra Harold Smith , Crispin Chamorro Paola Lisbeth , Huayanay Palma Lisseth Margarita
Published: February 2025

This article addresses the challenge of low overall equipment effectiveness (OEE) within the textile industry. It identifies the need to enhance equipment availability, quality, and performance to tackle sectoral challenges. The main objective of this research study aimed to develop and implement a management model based on total productive maintenance (TPM) and Six Sigma, using a textile company as a case study. A sample of 28 machines from the Weaving Department was taken and various tools were applied, including internal analysis, process flow diagram (PFD), failure mode and effects analysis (FMEA), Pareto analysis, cause-and-effect matrix, 5S, TPM, I-MR charts, and control plans. As a result, a remarkable increase of 9.09% in OEE was achieved, demonstrating specific improvements of 5.18% in equipment availability, 4.23% in performance, and 1.6% in quality.
Gadolinium-guided Transcatheter Aortic Valve Implantation in a Patient with Renal Impairment and a History of Severe Allergic Reaction to Iodinated Contrast Media
Authors: Alshehri Bandar , Alamri Hussein , Alghasab Naif , Ahmed Jamal , Alshehri Fahad , Samargandy Sondos , Almoghairi Abdulrahman M
Published: February 2025

Iodinated contrast media is integral to the evaluation for transcatheter aortic valve implantation; however, some patients may have contraindications to the use of iodinated contrast media. The study reports successful use of a gadolinium-based contrast agent in a patient with severe symptomatic aortic stenosis, contrast allergy and post-contrast acute kidney injury.
Patent Foramen Ovale Closure: British Cardiovascular Intervention Society Position Statement
Authors: Turner Mark , Aggarwal Suneil K , Mullen Michael J , Malik Iqbal , MacCarthy Philip , Northridge David , Spence Mark S , Rana Bushra , Hildick-Smith David
Published: February 2025

The foramen ovale is a flap in the atrial septum that is open in the fetus to allow oxygenated blood returning from the placenta to pass to the systemic circulation. In early life, the primum septal flap should close, but in 25% of people the flap does not seal fully. Most patent foramen ovale (PFO) are small and open only following Valsalva. Resting right-to-left shunts are less common, occurring in 5% of individuals. This British Cardiovascular Intervention Society position statement describes the diagnosis, indications and procedure for PFO closure.
ТАКИМ МИ ЙОГО ПАМ’ЯТАЄМО
Authors: Дзюба А. П.
Published: February 2025

пам’яті член-кореспондента НАН України, д-ра техн.. наук, професора Вадима Сергійовича Гудрамовича
Contribución de la responsabilidad social a los objetivos de desarrollo sostenible en la empresa familiar costarricense: un estudio de casos
Authors: Mora Ortega Tania , De la O Cordero Dyalá , Ramírez Guzmán Camila
Published: February 2025

Mediante un estudio de casos, el artículo pretende identificar las actividades de responsabilidad social que realizan seis empresas familiares costarricenses para determinar su contribución con los Objetivos de Desarrollo Sostenible (ODS) de la Agenda 2030 de la Organización de Naciones Unidas (específicamente objetivo 3- salud y bienestar, 4- educación de calidad, 5- igualdad de género y por último el objetivo 8- trabajo decente y crecimiento económico). La investigación se desarrolló mediante entrevistas a profundidad a seis empresas familiares costarricenses. Los resultados obtenidos señalan que las prácticas de responsabilidad social que implementan las empresas estudiadas pueden aportar significativamente a la consecución de los ODS mencionados. Asimismo, los resultados abren oportunidades para nuevas líneas de investigación en estos temas.
EL ONUS PROBANDI EN EL DERECHO DEL TRABAJO
Authors: Amézquita Garnica Lesbia Guadalupe
Published: February 2025

En los últimos años se ha impulsado a nivel nacional, regional y global un debate que busca someter nuevamente los derechos reconocidos al trabajo a la autonomía (...)
Percepciones del estudiantado sobre el «feedback» sostenible: un análisis de redes en una universidad española
Authors: Cano-García Elena , Ianos Maria-Adelina
Published: February 2025

El estudio pretende describir las prácticas de feedback en una universidad española y analizar su alineación con los principios del feedback sostenible. Se recopilaron datos de 261 estudiantes a través de un cuestionario en línea. Además de análisis descriptivos, se realizó un análisis de redes psicométricas para capturar la naturaleza dinámica e interactiva del feedback sostenible. Los resultados indican que, si bien los estudiantes interactúan con diversas fuentes y muestran esfuerzos hacia la autorregulación, el profesorado desempeña un papel central en las prácticas de feedback. Estos hallazgos destacan la importancia de intensificar los esfuerzos para promover el feedback sostenible.
Efecto del interés hacia los contenidos, valor atribuido a las tareas, control sobre el aprendizaje y procrastinación en la autorregulación académica de estudiantes universitarios
Authors: González-Franco Verónica , Sotelo-Castillo Mirsha-Alicia , Echeverría-Castro Sonia-Beatriz , Barrera-Hernández Laura-Fernanda
Published: February 2025

Introducción. Entre las habilidades que busca fomentar la educación integral se encuentra la autorregulación, por ello, se tuvo el objetivo de analizar el efecto que recibe la autorregulación de las variables independientes: interés hacia los contenidos, valor atribuido a las tareas, control sobre el aprendizaje y procrastinación. Materiales y método. Se realizó un estudio cuantitativo con una muestra de 505 estudiantes universitarios del norte de Sonora (México). Resultados. El modelo resultante incluye todas las variables independientes propuestas, explicando el 36% de la autorregulación académica. Discusión. Es indispensable continuar con el estudio y el fomento de las estrategias autorregulatorias de los estudiantes universitarios.
Factores asociados a la intención de abandonar los estudios superiores: la motivación y la resiliencia
Authors: F.-Rivas Silvia , Blanco Elena , Bernardo Ana-B.
Published: February 2025

Para ahondar en la complejidad del abandono universitario, se analiza el impacto conjunto de la motivación y la resiliencia sobre la intención de transferencia y de abandono. Con una muestra de 477 estudiantes españoles se aplicaron pruebas t y modelos de regresión logística. Los resultados multivariantes indican que la motivación intrínseca y la amotivación explican el 44,4% de la intención de transferencia y la motivación intrínseca, la regulación externa y la amotivación, el 48,1% de la intención de abandono. Estos altos porcentajes sugieren que fomentar la motivación intrínseca y prevenir la amotivación son esenciales para reducir las tasas de abandono.
“CUIDAR NO TODO”
Authors: Garcia Castro Liana , Kramer Sonia , Rezende Nunes Maria Fernanda , Scramingnon Gabriela
Published: February 2025

O artigo apresenta um recorte de uma pesquisa interinstitucional, que teve como objetivo conhecer as histórias de vida de crianças, seus/suas professores/as e suas famílias, identificando e compreendendo as marcas presentes do cuidar e ser cuidado em narrativas de crianças e adultos que frequentam creches, pré-escolas e escolas. Neste estudo, a compreensão do cuidado tem sido construída no diálogo com Mikhail Bakhtin e Martin Buber, autores que sustentam as relações dialógicas como premissa para uma existência que seja uma resposta responsável ao tempo e ao lugar no qual vivemos. Na metodologia, seguiu-se a abordagem qualitativa, utilizando como estratégias entrevistas individuais e coletivas, oficinas e observação participante. O artigo focaliza narrativas de duas merendeiras de uma escola da rede municipal do Rio de Janeiro, que atende a Educação Infantil e os Anos Iniciais do Ensino Fundamental. As narrativas indicam que as merendeiras entrevistadas compreendem o preparo e a oferta da alimentação como práticas de cuidado, que envolvem não apenas cozinhar e servir o alimento, mas também interesse, atenção e reconhecimento das necessidades do outro, especialmente das crianças. A pesquisa, entretanto, aponta que a falta de profissionalização do cargo de merendeira pode contribuir para que uma lógica de espaço doméstico prevaleça nas relações e no próprio ato de cozinhar em uma instituição educacional, favorecendo condições de trabalho precárias e desvalorização de uma profissão fundamental na implementação do Plano Nacional de Alimentação Escolar (PNAE). Na contramão do desprestígio, as crianças da escola pesquisada reconhecem e valorizam os gestos de cuidado das merendeiras entrevistadas.
GUIA-INTERPRETAÇÃO E SEUS ATRAVESSAMENTOS
Authors: Regina Conrad Lourenço Katia , Caroline Alves Vasconcelos Stephanie , Oliveira Dias Jonathas
Published: February 2025

A guia-interpretação se faz presente de maneira fundamental na vida e no cotidiano de pessoas surdocegas, usuárias deste serviço e que, cada vez mais, adentram espaços formadores e instâncias de poder promotoras do debate de ideias como, por exemplo, as universidades, os eventos científicos e de conferência, por conta das políticas públicas em conjunto com ações de acessibilidade e inclusão. Logo, a participação destes indivíduos, nos leva a refletir sobre o trabalho dos guias-intérpretes na promoção do acesso nestes cenários e quais questões permeiam o oferecimento desse serviço. A partir da metodologia da pesquisa narrativa, de natureza expo-post-facto, esta investigação parte das experiências narradas de nove profissionais que atuaram diretamente com pessoas surdocegas em um congresso científico. Sendo assim, os objetivos deste estudo são: 1) entender os processos que envolvem o trabalho dos guias-intérpretes; 2) compreender quais desafios permeiam estas etapas; 3)  resgatar as estratégias utilizadas para o atendimento dos congressistas surdocegos; 4) refletir os aprendizados que este cenário possibilitou para os profissionais. Os resultados apontam para as reflexões emergentes dos participantes no que diz respeito ao seu papel profissional, ao impacto do trabalho em equipe, a tarefa das instituições no oferecimento do serviço e, por último, evidenciar subsídios para novas práticas formativas e atitudinais que valorizem e aprimorem o trabalho da guia-interpretação e o seu respectivo público-alvo.
O PAPEL DO PROJETO INTEGRADOR NA CONSTRUÇÃO DE COMPETÊNCIAS CRÍTICAS NA EDUCAÇÃO TÉCNICA
Authors: Ribeiro de Sá Ivo , Alexandre Felício Brito Carlos , Martinez Moraes Hugo
Published: February 2025

O Projeto Integrador (PI) no contexto do SENAC São Paulo é uma estratégia pedagógica que visa promover a integração curricular e o desenvolvimento de competências críticas e reflexivas nos cursos técnicos de saúde. Esta pesquisa qualitativa, baseada no Construtivismo Social, investigou as percepções de 24 professores sobre a implementação e os desafios do PI. Utilizando Análise de Conteúdo Automatizada com o software IRaMuTeQ, os resultados revelaram que os professores consideram o PI uma ferramenta crucial para a formação técnica, embora enfrentem desafios significativos, como a compreensão limitada dos alunos sobre o projeto e dificuldades na colaboração interdisciplinar. Os achados indicam a necessidade de maior integração da interdisciplinaridade e práticas de autoavaliação para fomentar um pensamento crítico mais profundo entre os estudantes.
A ENTREVISTA NARRATIVA DE FRITZ SCHÜTZE COMO PERCURSO METODOLÓGICO
Authors: De Barros Munari Keith
Published: February 2025

Este escrito consiste numa contribuição metodológica para o campo das investigações qualitativas em educação trazendo um recorte de uma pesquisa de doutoramento, defendida em 2020, que utilizou o método preconizado pelo sociólogo alemão Fritz Schütze da Entrevista Narrativa (EN). A pesquisa buscou ampliar compreensões acerca dos movimentos da profissionalização docente, num recorte temporal de trinta anos (1989-2019), sobretudo de fatores que permeiam a permanência na profissão e para tanto, questionou como a profissionalização docente estava sendo percebida frente às trajetórias profissionais. O referencial teórico esteve pautado em achados que discutem profissionalização, formação e profissão docentes.  A pesquisa contou com narrativas de quatro professoras formadoras que, ao compartilharem suas trajetórias trouxeram à tona percepções que permitiram inferências acerca do estar na profissão. Como resultado, o corpus analítico, construído por meio das narrativas, permitiu reflexões sobre fatores que tentam explicar a profissão docente, valendo ressaltar que a permanência na profissão se encontrava ancorada principalmente no aprimoramento profissional, uma vez que, as participantes buscavam pelo cumprimento do compromisso que assumiram com a educação ao escolherem a profissão docente, o que nos permitiu traçar inferências que vão ao encontro da ideia de que o movimento de profissionalização tem sido um processo de construção contínua e ininterrupta. Objetivamos com este escrito, apresentar o panorama teórico da metodologia adotada na pesquisa elucidando a sistematização e aplicabilidade da EN, servindo de guia para futuros pesquisadores que intentam trabalhar com interpretações de narrativas, sobretudo quando discutem temas atrelados à formação de professores.
Dinâmica de partos em região ribeirinha da Amazônia brasileira na perspectiva da geoespacialização
Authors: Lopes Liandra Silva , Nogueira Laura Maria Vidal , Andrade Erlon Gabriel Rego de , Rodrigues Ivaneide Leal Ataíde , Guedes Juan Andrade , Caldas Rosinelle Janayna Coêlho , Silva Paula Gisely Costa
Published: February 2025

RESUMO Objetivo: analisar o padrão espaço-temporal de partos e o fluxo de parturientes atendidas em uma maternidade de referência regional. Métodos: estudo ecológico de 4.081 partos realizados no período de setembro/2018 a dezembro/2021 em maternidade pública na região Baixo Tocantins, Pará, Brasil. Com dados coletados em cinco fontes, construiu-se banco de dados geográficos e empregou-se análise espacial com o interpolador de densidade Kernel. Mapas foram gerados nos softwares QGis/3.5 e TerraView/4.3, calculando-se o qui-quadrado (p<0,05). Resultados: as maiores concentrações de partos, pelas vias normal e cesariana, foram evidenciadas em Barcarena (n=2.558/62,68%), Abaetetuba (n=750/18,38%), Moju (n=363/8,89%) e Igarapé-Miri (n=219/5,37%). Entre os municípios da região, dez dispunham de leitos obstétricos, totalizando 210 leitos. Nesse cenário, as parturientes percorriam até 288 km para chegar à maternidade. Conclusões: longas distâncias entre certos municípios de residência e a maternidade, e a baixa oferta de leitos obstétricos, foram identificadas como fatores de risco para desfechos obstétricos desfavoráveis.
Espaços e limites da empresa capitalista na agricultura
Authors: AIDAR ANTONIO CARLOS KFOURI , PEROSA JUNIOR ROBERTO MARIO
Published: February 2025

RESUMO Com base nas discussões no mundo desenvolvido e na economia brasileira em torno da sustentabilidade do empreendimento capitalista no setor agrícola e nas políticas governamentais, este estudo visa proporcionar uma melhor compreensão do setor agrícola nos Estados Unidos. Com isso, buscamos estabelecer teorias em torno das tendências do desenvolvimento da produção agrícola em uma economia capitalista.