bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Social Loneliness on Tourist Happiness: A Mediation Analysis Based on Smartphone Usage
Authors: Chen Xuejiao , Zhang Kai , Huang Yanting
Published: May 2023

Smartphone usage affects the relationship between social loneliness in tourism and tourist happiness. This study discusses the effect of social loneliness on tourist happiness by considering three aspects of smartphone usage—habitual smartphone behaviors, smartphone communication, and smart tourism applications—as mediating variables. Based on stimulus–organism–response theory, this study collected data through questionnaires, analyzed the data using SPSS and Amos, and reached three findings, as follows: (1) Social loneliness affects tourist happiness either directly or indirectly. (2) Habitual smartphone behaviors not only directly affect tourist happiness but also affect tourist happiness as a mediating variable and multiple mediating variables. (3) Smartphone communication does not affect tourist happiness either directly or indirectly as a mediating variable or as one of multiple mediating variables of social loneliness. (4) Smart tourism applications not only directly affect tourist happiness but also affect tourist happiness indirectly as one of multiple mediating variables. This study is not only conducive to exploring social loneliness and the influence mechanism of social loneliness on tourist happiness, but it is also conducive to suggesting that scenic spots should add interesting group activities in project development to reduce social loneliness. Attention should also be paid to social loneliness in destination marketing.
The Feasibility Analysis of “Ecological Photovoltaics” from Coal Gangue Mountains
Authors: Shi Fang , Li Xiaodan , Cao Ying , Bai Bo
Published: May 2023

Coal gangue is a byproduct of coal mining, and has been piled up for years in China, forming thousands of coal gangue hills, which have become an important part of abandoned mining areas. In recent years, the government has issued various policies on the ecological restoration of coal gangue hills and provided economic support. However, relying solely on policies and economic support is not a long-term solution. The key is to improve the production efficiency of coal gangue hills and promote their sustainable development. This paper conducts on-site investigations of coal gangue hills and makes proposals from the perspective of ecology and economic benefits. Firstly, it is suitable to install photovoltaics on coal gangue hills, especially those located far from residential areas, with convenient transportation and maintenance and the orientation of the coal gangue mountain. Secondly, based on the preliminary ecological restoration of coal gangue hills, a design scheme of laying photovoltaic cells on the slopes of coal gangue hills and developing ecological platforms through planting is proposed. The feasibility is explored by constructing a net present value economic calculation. The results show that the use of a slope photovoltaic laying design scheme is not only conducive to ecological development, but also can cover the daily maintenance costs of coal gangue hill ecological restoration and produce certain economic benefits. With the expansion of the scale and the improvement of location conditions, the economic benefits will also increase.
Effects of Vertical Fiscal Imbalance on Green Total Factor Productivity—Evidence from China
Authors: Yang Zhao
Published: May 2023

Green development is the key to safeguarding and improving people’s livelihoods and promoting sustainable development. Based on the provincial data of China for 2004–2019, we developed a general panel model and spatial Durbin model to test the effects of vertical fiscal imbalance (VFI) on green total factor productivity (GTFP). The results show that VFI has a significant inhibitory effect on GTFP; decomposing GTFP into the green technical efficiency change (GEC) and green technological change (GTC) indices reveals that the inhibitory effect of VFI on the GEC and GTC indices is significant and non-significant, respectively; the dampening effect of VFI on GTFP is more significant in regions with high economic growth target, low marketization, or high levels of VFI, and in Midwest, resource-based, or non-municipalities regions. The results of the spatial spillover effect analysis show that VFI has a suppressive effect on GTFP in regions with similar levels of economic development. This study enriches the existing literature by exploring the institutional causes affecting GTFP levels and provides theoretical and practical implications for comprehensively promoting a new round of fiscal system reforms in China and building a modern fiscal system with clear authority and responsibility, thereby promoting sustainable development.
Entrepreneurial Strategic Orientation: Prerequisite for SMEs Success in IoT and Digital Transformation Sphere?
Authors: Cvijić Čović Mirjana , Borocki Jelena , Djaković Vladimir , Vekić Aleksandar , Okanović Andrea
Published: May 2023

Entrepreneurial orientation (EO) is a multidimensional construct that reflects a firm’s tendency to be innovative, proactive, and risk-taking. Previous research has demonstrated that companies with a strong EO possess a competitive advantage in the market when compared to those with a conservative approach to management. The objective of this study is to analyse the entrepreneurial orientation of small and medium-sized enterprises (SMEs) using the ENTRE-U scale and to identify the dimensions of EO that are critical for achieving business success in the context of digital transformation and IoT implementation. The identification of these dimensions is facilitated through a survey method and exploratory factor analysis. After administering the ENTRE-U scale to a representative sample of SMEs that use modern technologies, such as IoT, four distinct dimensions of EO emerged. Each dimension of EO has a significant impact on firm performance. By adhering to the established EO dimensions and using the proposed methodology, managers can develop an efficient business model that aligns with the current digital market demands, enhances SMEs (survival, resilience, and sustainability), and addresses the high uncertainty prevalent in today’s business environment.
Searching for the Predictors of Response to BoNT-A in Migraine Using Machine Learning Approaches
Authors: Martinelli Daniele , Pocora Maria Magdalena , De Icco Roberto , Allena Marta , Vaghi Gloria , Sances Grazia , Castellazzi Gloria , Tassorelli Cristina
Published: May 2023

OnabotulinumtoxinA (BonT-A) reduces migraine frequency in a considerable portion of patients with migraine. So far, predictive characteristics of response are lacking. Here, we applied machine learning (ML) algorithms to identify clinical characteristics able to predict treatment response. We collected demographic and clinical data of patients with chronic migraine (CM) or high-frequency episodic migraine (HFEM) treated with BoNT-A at our clinic in the last 5 years. Patients received BoNT-A according to the PREEMPT (Phase III Research Evaluating Migraine Prophylaxis Therapy) paradigm and were classified according to the monthly migraine days reduction in the 12 weeks after the fourth BoNT-A cycle, as compared to baseline. Data were used as input features to run ML algorithms. Of the 212 patients enrolled, 35 qualified as excellent responders to BoNT-A administration and 38 as nonresponders. None of the anamnestic characteristics were able to discriminate responders from nonresponders in the CM group. Nevertheless, a pattern of four features (age at onset of migraine, opioid use, anxiety subscore at the hospital anxiety and depression scale (HADS-a) and Migraine Disability Assessment (MIDAS) score correctly predicted response in HFEM. Our findings suggest that routine anamnestic features acquired in real-life settings cannot accurately predict BoNT-A response in migraine and call for a more complex modality of patient profiling.
Identification of the Flavone-Inducible Counter-Defense Genes and Their cis-Elements in Helicoverpa armigera
Authors: Deng Zhongyuan , Zhang Yuting , Fang Liying , Zhang Min , Wang Lixiang , Ni Xinzhi , Li Xianchun
Published: May 2023

Flavone is widely found in plants and plays an important role in plant defense against pests. Many pests, such as Helicoverpa armigera, use flavone as a cue to upregulate counter-defense genes for detoxification of flavone. Yet the spectrum of the flavone-inducible genes and their linked cis-regulatory elements remains unclear. In this study, 48 differentially expressed genes (DEGs) were found by RNA-seq. These DEGs were mainly concentrated in the retinol metabolism and drug metabolism-cytochrome P450 pathways. Further in silico analysis of the promoter regions of 24 upregulated genes predicted two motifs through MEME and five previously characterized cis-elements including CRE, TRE, EcRE, XRE-AhR and ARE. Functional analysis of the two predicted motifs and two different versions of ARE (named ARE1 and ARE2) in the promoter region of the flavone-inducible carboxylesterase gene CCE001j verified that the two motifs and ARE2 are not responsible for flavone induction of H. armigera counter-defense genes, whereas ARE1 is a new xenobiotic response element to flavone (XRE-Fla) and plays a decisive role in flavone induction of CCE001j. This study is of great significance for further understanding the antagonistic interaction between plants and herbivorous insects.
Yang–Mills Instantons in the Dual-Superconductor Vacuum Can Become Confining
Authors: Antonov Dmitry
Published: May 2023

As known, the realistic, exponential, fall-off of the rate of production of light mesons in the chromo-electric field of a quark–antiquark string, as a function of the meson mass, can be obtained from the Schwinger-formula Gaussian fall-off within a phenomenological approach which assumes a certain distribution of the string tension. This approach gets a clear meaning in the London limit of the dual superconductor, where the logarithmic increase of the chromo-electric field towards the core of the string leads precisely to the change of the Gaussian fall-off to the exponential one, thus allowing for an identification of the phenomenological distribution of the string tension. In this paper, we demonstrate that, for this distribution of the string tension, the distribution of large-size Yang–Mills instantons, which are interacting with the confining monopole background, becomes O(1/ρ3), where ρ is the size of an instanton. Since such a distribution of large-size instantons is known to yield confinement, we conclude that, in the London limit of the dual-superconductor vacuum, instantons can form a confining medium, and we evaluate their contribution to the total string tension.
In Situ Structures of the Ultra-Long Extended and Contracted Tail of Myoviridae Phage P1
Authors: Yang Fan , Wang Liwen , Zhou Junquan , Xiao Hao , Liu Hongrong
Published: May 2023

The Myoviridae phage tail is a common component of contractile injection systems (CISs), essential for exerting contractile function and facilitating membrane penetration of the inner tail tube. The near-atomic resolution structures of the Myoviridae tail have been extensively studied, but the dynamic conformational changes before and after contraction and the associated molecular mechanism are still unclear. Here, we present the extended and contracted intact tail-structures of Myoviridae phage P1 by cryo-EM. The ultra-long tail of P1, 2450 Å in length, consists of a neck, a tail terminator, 53 repeated tail sheath rings, 53 repeated tube rings, and a baseplate. The sheath of the contracted tail shrinks by approximately 55%, resulting in the separation of the inner rigid tail tube from the sheath. The extended and contracted tails were further resolved by local reconstruction at 3.3 Å and 3.9 Å resolutions, respectively, allowing us to build the atomic models of the tail terminator protein gp24, the tube protein BplB, and the sheath protein gp22 for the extended tail, and of the sheath protein gp22 for the contracted tail. Our atomic models reveal the complex interaction network in the ultra-long Myoviridae tail and the novel conformational changes of the tail sheath between extended and contracted states. Our structures provide insights into the contraction and stabilization mechanisms of the Myoviridae tail.
SARS-CoV-2 Detection and Culture in Different Biological Specimens from Immunocompetent and Immunosuppressed COVID-19 Patients Infected with Two Different Viral Strains
Authors: Mendes-Correa Maria Cássia , Salomão Matias Chiarastelli , Ghilardi Fábio , Tozetto-Mendoza Tania Regina , Santos Villas-Boas Lucy , de Paula Anderson Vicente , Paiao Heuder Gustavo Oliveira , da Costa Antonio Charlys , Leal Fábio E. , Ferraz Andrea de Barros Coscelli , Sales Flavia C. S. , Claro Ingra M. , Ferreira Noely E. , Pereira Geovana M. , da Silva Almir Ribeiro , Freire Wilton , Espinoza Evelyn Patricia Sánchez , Manuli Erika R. , Romano Camila M. , de Jesus Jaqueline G. , Sabino Ester C. , Witkin Steven S.
Published: May 2023

Introduction—The dynamics of SARS-CoV-2 shedding and replication in humans remain incompletely understood. Methods—We analyzed SARS-CoV-2 shedding from multiple sites in individuals with an acute COVID-19 infection by weekly sampling for five weeks in 98 immunocompetent and 25 immunosuppressed individuals. Samples and culture supernatants were tested via RT-PCR for SARS-CoV-2 to determine viral clearance rates and in vitro replication. Results—A total of 2447 clinical specimens were evaluated, including 557 nasopharyngeal swabs, 527 saliva samples, 464 urine specimens, 437 anal swabs and 462 blood samples. The SARS-CoV-2 genome sequences at each site were classified as belonging to the B.1.128 (ancestral strain) or Gamma lineage. SARS-CoV-2 detection was highest in nasopharyngeal swabs regardless of the virus strain involved or the immune status of infected individuals. The duration of viral shedding varied between clinical specimens and individual patients. Prolonged shedding of potentially infectious virus varied from 10 days up to 191 days, and primarily occurred in immunosuppressed individuals. Virus was isolated in culture from 18 nasal swab or saliva samples collected 10 or more days after onset of disease. Conclusions—Our findings indicate that persistent SARS-CoV-2 shedding may occur in both competent or immunosuppressed individuals, at multiple clinical sites and in a minority of subjects is capable of in vitro replication.
DEFICIÊNCIA INTELECTUAL E TEORIA HISTÓRICO-CULTURAL: um resgate aos textos de Vigotski
Authors: Abreu Fabrício Santos Dias de , Pederiva Patrícia Lima Martins
Published: May 2023

O presente artigo busca analisar o conjunto de textos escritos, entre os anos 20 e 30 do século XX, em que L. S. Vigotski (1896-1934) aborda a questão da deficiência intelectual na tentativa de apontar que o teórico inaugura uma interpretação à frente do seu tempo histórico e que muitas das discussões engendradas por ele tomaram vigor apenas no século XXI com o advento das políticas de inclusão e acessibilidade. O esforço é demonstrar que a totalidade desses escritos aponta para a necessidade de reformulação de atitudes pedagógicas e terapêuticas que focalizam suas práticas apenas nos processos biológicos ou naquilo que se considera deficitário e passível de ajustamentos. O entendimento revolucionário encontra-se em afirmar que as leis que regem o desenvolvimento do ser social não fazem distinções de pessoas, são únicas para todos os indivíduos, e dependem necessariamente da qualidade dos processos mediacionais que se efetivam no intercâmbio entre os humanos. Onde outras teorias postulam a defesa de uma educação reduzida, em conteúdos e interações, a Teoria Histórico-Cultural sustenta que as dificuldades oriundas da deficiência intelectual podem ser compensadas por meio do pleno desenvolvimento social que se efetiva em um meio inclusivo e colaborativo.
Creating Opportunities Through an Experiential, Community-Based Cooperative Extension Internship Program
Authors: Sellers Debra , Heronemus Cheryl , Gannon Cindy , Lockhart Peggy
Published: May 2023

Extension is positioned to develop and implement high-quality, high-impact internship experiences for college students in local communities. The creation of the Rising Star Internship program arose from interest in providing experiential work opportunities for Iowa State University students coupled with the organizational goals of promoting awareness of Cooperative Extension and increasing interest in employability within Extension. The program provides a paid county-level summer internship with several unique elements. Evidence collected from student participants suggests that it is a mutually beneficial endeavor for Extension, students, and communities. Extension systems may desire to replicate these efforts if they share similar ambitions.
Can long-term musculoskeletal, spinal pain improve with movement education using SEMG biofeedback?
Authors:   , Ellis Rowan
Published: May 2023

The research explained the impact of using surface electromyography (SEMG) as a biofeedback tool to improve long-term musculoskeletal, spinal pain. The study aimed to understand the impact of using SEMG within the context of biofeedback rehabilitation of musculoskeletal pain. Methods/Methodology: the project utilised a Phenomenological paradigm and an Action Research methodology/framework of investigation, action and reflection. The data collection included mixed methods of SEMG recordings, pain questionnaire, well-being scale and participant self-assessment. There were nine participants in the study, eight female and one male; the mean age of participants was 54 years. All participants had been undertaking rehabilitative training for a minimum of three years; however, all have some minimal to moderate musculoskeletal, spinal pain remaining. The findings confirmed that using SEMG as a biofeedback modality in treating long-term musculoskeletal, spinal pain is beneficial. SEMG biofeedback is extremely helpful to people suffering from musculoskeletal, spinal pain. SEMG biofeedback enables individuals to discover activities at home, work and in the gym which cause them muscular stress, which they did not know. SEMG biofeedback encourages learning new movements, altering and training new neural pathways, and enabling greater muscular control. In addition, an improvement in muscular awareness from SEMG biofeedback correlates with improved back pain. Musculoskeletal pain is multifactorial. Pain can have multiple causes, including poor sleep, emotional stress, depression, anxiety, and low muscular and physical awareness. This study has improved the user experience for SEMG devices by providing real-time data analysis software.
Acceptor Engineering Produces Ultrafast Nonradiative Decay in NIR-II Aza-BODIPY Nanoparticles for Efficient Osteosarcoma Photothermal Therapy via Concurrent Apoptosis and Pyroptosis
Authors: Shi Zhenxiong , Bai Hua , Wu Jiaxing , Miao Xiaofei , Gao Jia , Xu Xianning , Liu Yi , Jiang Jiamin , Yang Jiaqi , Zhang Jiaxin , Shao Tao , Peng Bo , Ma Huili , Zhu Dan , Chen Guojing , Hu Wenbo , Li Lin , Huang Wei
Published: May 2023

Small-molecule photothermal agents (PTAs) with intense second near-infrared (NIR-II, 1,000 to 1,700 nm) absorption and high photothermal conversion efficiencies (PCEs) are promising candidates for treating deep-seated tumors such as osteosarcoma. To date, the development of small-molecule NIR-II PTAs has largely relied on fabricating donor–acceptor–donor (D–A–D/D′) structures and limited success has been achieved. Herein, through acceptor engineering, a donor–acceptor–acceptor (D–A–A′)-structured NIR-II aza-boron-dipyrromethene (aza-BODIPY) PTA (SW8) was readily developed for the 1,064-nm laser-mediated phototheranostic treatment of osteosarcoma. Changing the donor groups to acceptor groups produced remarkable red-shifts of absorption maximums from first near-infrared (NIR-I) regions (~808 nm) to NIR-II ones (~1,064 nm) for aza-BODIPYs (SW1 to SW8). Furthermore, SW8 self-assembled into nanoparticles (SW8@NPs) with intense NIR-II absorption and an ultrahigh PCE (75%, 1,064 nm). This ultrahigh PCE primarily originated from an additional nonradiative decay pathway, which showed a 100-fold enhanced decay rate compared to that shown by conventional pathways such as internal conversion and vibrational relaxation. Eventually, SW8@NPs performed highly efficient 1,064-nm laser-mediated NIR-II photothermal therapy of osteosarcomaviaconcurrent apoptosis and pyroptosis. This work not only illustrates a remote approach for treating deep-seated tumors with high spatiotemporal control but also provides a new strategy for building high-performance small-molecule NIR-II PTAs.
Tipping Point Detection Using Reservoir Computing
Authors: Li Xin , Zhu Qunxi , Zhao Chengli , Qian Xuzhe , Zhang Xue , Duan Xiaojun , Lin Wei
Published: May 2023

Detection in high fidelity of tipping points, the emergence of which is often induced by invisible changes in internal structures or/and external interferences, is paramountly beneficial to understanding and predicting complex dynamical systems (CDSs). Detection approaches, which have been fruitfully developed from several perspectives (e.g., statistics, dynamics, and machine learning), have their own advantages but still encounter difficulties in the face of high-dimensional, fluctuating datasets. Here, using the reservoir computing (RC), a recently notable, resource-conserving machine learning method for reconstructing and predicting CDSs, we articulate a model-free framework to accomplish the detection only using the time series observationally recorded from the underlying unknown CDSs. Specifically, we encode the information of the CDS in consecutive time durations of finite length into the weights of the readout layer in an RC, and then we use the learned weights as the dynamical features and establish a mapping from these features to the system’s changes. Our designed framework can not only efficiently detect the changing positions of the system but also accurately predict the intensity change as the intensity information is available in the training data. We demonstrate the efficacy of our supervised framework using the dataset produced by representative physical, biological, and real-world systems, showing that our framework outperforms those traditional methods on the short-term data produced by the time-varying or/and noise-perturbed systems. We believe that our framework, on one hand, complements the major functions of the notable RC intelligent machine and, on the other hand, becomes one of the indispensable methods for deciphering complex systems.
Uji Performa Prediksi Gempa Bumi di Jawa Timur dengan Artificial Neural Network
Authors: Permana Muhammad Aji , Faisal M
Published: May 2023

East Java Province is an area directly adjacent to the Eurasian and Indo-Australian plate subduction zones, this has resulted in East Java province being an area prone to earthquakes. Predictions regarding the frequency of earthquake occurrences are very interesting to study. This needs to be done in order to increase our preparedness in an effort to reduce the risk of earthquakes. Research on earthquake prediction has been carried out, one of which is the artificial neural network method. The purpose of this study is to obtain the best network architecture that is applied to the data on the frequency of earthquake occurrences per month in East Java Province. Data on earthquake occurrences come from the BMKG Nganjuk Geophysics Station, which was recorded during the 2016-2021 period. The data was then grouped into the total frequency of events per month. The criteria for selecting the best network architecture are carried out by comparing each possible architecture's error values. The test method uses SSE (sum square error) criteria for each architectural model of the artificial neural network. The test results show that the input variation has a significant contribution and a greater correlation than the variation in the number of hidden neurons. The best prediction results are obtained in the model with 9-30-1 architecture with an error value of 0.1958.
Dalgacık Paket Dönüşümü, ReliefF Özellik Seçimi ve Topluluk Öğrenme Algoritması Tabanlı Bir Kısmi Deşarj Arızası Tespit Yöntemi
Authors: ERİŞTİ Belkıs
Published: May 2023

Enerji nakil hatlarında birçok arıza olayı meydana gelebilmektedir. Özellikle hatlarda faz iletkenlerinin çevresel bitki örtüleriyle ve birbirleriyle temas etmeleri sonucunda oluşan arızalar sıklıkla meydana gelir. Bu şekilde oluşabilecek arızaların önüne geçebilmek için özellikle enerji nakil hatlarında izolasyonlu iletkenler yaygın olarak kullanılmaktadır. Ancak izolasyonlu iletkenlerin yalıtım malzemesinde meydana gelebilecek deformasyonlar bu iletkenlerde kısmi deşarj (KD) adı verilen olaylara sebep olabilirler. Oluşabilecek çok daha büyük arızaların önüne geçebilmek için KD’lerin hızlı bir şekilde tespit edilmesi gerekir. Bu çalışmada, iletim hatlarında meydana gelen KD’lerin tespiti için dalgacık paket dönüşümü (DPD), ReliefF özellik seçim yaklaşımı ve topluluk öğrenme algoritma sınıflandırıcı tabanlı etkili bir tespit yaklaşımı önerilmiştir. Bu yaklaşımın en önemli özelliği, KD verilerinin DPD kullanarak etkili frekans bantlarına dayanan özellikler elde edilmesi ve ReliefF yaklaşımı kullanılarak bu özellikler içerisinden tespit performansı yüksek özelliklerin seçilmesidir. Önerilen tespit sistemi VSB gerçek veri seti kullanılarak test edilmiş ve 89.22% doğruluk oranı elde edilmiştir. Literatürde VSB veri seti kullanan benzer çalışmalarla karşılaştırıldığında başarımın oldukça yüksek olduğu ve önerilen yaklaşımın KD tespiti için etkili bir performans sergilediği görülmüştür.
Çift Kabuk Cephe Sistemlerinin Sıcak ve Soğuk İklim Bölgeleri için Isıl Performanslarının İncelenmesi
Authors: YÜKSEL Elif Nur , BEKTAŞ EKİCİ Betül
Published: May 2023

Çift kabuk cepheler bina enerji performansı ve konfor koşullarının iyileştirilmesi için geliştirilmiş etkin sistemlerdir. Uygun bileşenlerle donatıldıkları, doğru yönlendirilip boyutlandırıldıkları takdirde bina ısıl yüklerinin azaltılması, iç hava kalitesinin arttırılması, gürültü ve güneş kontrolünün sağlanması noktasında önemli katkılar sağlamaktadırlar. Bu çalışmanın amacı son yıllarda kullanımı yaygınlaşan bu sistemlerinin sıcak ve soğuk iklim bölgeleri için performanslarının değerlendirilmesidir. Bu amaçla farklı derece gün bölgelerinde bulunan Adana (sıcak bölge) ve Erzurum (soğuk bölge) illerine ait coğrafi ve iklim koşullarında bir ofis binası örneği üzerinden simülasyonlar yapılmıştır. Çift kabuk cephelerin her bir bölge için 8 farklı yönlenme ve boşluk genişliği ile oluşturulan alternatif durumlarına ait ısıtma ve soğutma enerjisi ihtiyaçları Design Builder yazılımı ile belirlenmiştir. Sonuç olarak sıcak iklim bölgesindeki Adana koşullarında ısıl yükler içinde %92.91 oranında önemli yer tutan soğutma yüklerinin azaltılması için en uygun yönlenmenin kuzey, Erzurum için ise hem ısıtma hem de soğutma amaçlı ihtiyaç duyulan enerji miktarının optimize edilmesi için en uygun yönlenmenin güney yönüne doğru olacağı belirlenmiştir. Çift kabuk performansını etkileyen önemli parametrelerden olan boşluk genişliğinin en uygun değerinin iki bölge için de 60 cm olduğu tespit edilmiştir.
Students’ Perceptions on Virtual Discussion of Learning English for Specific Purposes
Authors: Zulfa Puspa Fortuna
Published: May 2023

The learning process in this pandemic era triggers the enhancement of technology utilization. The virtual learning classroom is then used for compensating the absence of face to face learning process. It also happens in the learning process for English for specific purposes (ESP). This research is aimed at finding out and describing the students’ perceptions about virtual discussion conducted by the lecturer for some meetings according to the campus’ syllabus. The data is collected from questionnaire-interview (Questaview) containing some questions to enlist students’ views which are distributed to 3 classes, they are two Information System classes and an Accounting Information System class. The sample of this research is just 30% of the entire students which are 22 students. Then, for analyzing the data, the researcher describes the students’ opinion on virtual discussion of learning English for specific purposes and uses Likert scale. The result shows that virtual discussion has positive and negative effects to comprehend the material, less acceptance of English material, less practice, yet the flexibility of learning time and re-reading material can be approved by the students. At the last opinion, the students state their wishes in conducting double ways consecutively, both online and offline for obtaining the useful benefits from those two.
Peningkatkan Jumlah Telur Dan Larva Ikan Lele Dumbo (Clarias gariepinus) Melalui Penambahan Tepung Kunyit (Curcuma domestika) dan Hormon Tiroksin pada Pakan Induk
Authors: Awaludin Awaludin , Santi Santi , Maulianawati Diana
Published: May 2023

Produksi ikan lele sering kali terhambat di kegiatan pembenihan yaitu disebabkan oleh tingginya tingkat kematian larva pada minggu-minggu pertama setelah penetasan karena yolk pada telur yang berfungsi sebagai cadangan makanan sedikit sehingga menyebabkan larva kekurangan cadangan makanan. Oleh karena itu diperlukan usaha yang intensif dalam meningkatkan produksi benih ikan lele. Penelitian ini bertujuan untuk meningkatkan jumlah telur dan larva ikan lele dengan penggunaan tepung kunyit dan hormon tiroksin pada pakan. Penelitian ini menggunakan 4 perlakuan dengan dosis P1 (Kontrol atau tanpa pemberian tepung kunyit dan hormon tioksin), P2 (penambahan kunyit 4.8 g/kg pakan), P3 (penambahan tiroksi 0,1 mg/kg pakan) dan P4 (penambahan kunyit 4,8 g/kg pakan dan tiroksi 0,1 mg/kg pakan). Hasil penelitian menunjukkan berat induk pada akhir penelitian P1 (600 g), P2 (625 g), P3 (631 g) dan P4 (650 g). Fekunditas telur yang dihasilkan pada penelitian ini yaitu P1 (25.493 butir), P2 (27.242 butir), P3( 27.648 butir) dan P4 (30,081 butir). Diameter telur ikan hasil perlakuan yaitu P1 (0,041 mm), P2 (0,042 mm), P3 (0,041 mm) dan P4 (0,043 mm). Jumlah larva yang dihasilkan P1 (20.151 individu), P2 (24.320 individu), P3 (25,503 individu) dan P4 (29.485 individu). Berdasarkan hasil penelitian dapat disimpulkan bahwa dengan penambahan tepung kunyit dan hormon tiroksin pada pakan dapat meningkatkan kualitas telur dan larva ikan lele.
Kelimpahan Clownfish (Amphiprioninae ocellaris) sebagai Bioindikator Kondisi Karang di Gili Labak, Madura
Authors: Vernandha Yunita Vernandha , Wijaya Nirmalasari Idha
Published: May 2023

Terumbu karang merupakan habitat bagi lebih dari 300 jenis karang, 200 jenis ikan, dan berbagai macam invertebrata lain seperti moluska, krustasea, spons, alga, dan biota lainnya. Anemon laut adalah hewat laut dari anggota taksonomi kelas Anthozoa, yang berbentuk bunga. Clownfish mempunyai daya tarik pada warna mempunyai corak warna dasar dengan kombinasi: merah – putih, merah – hitam dan hitam – kuning – putih. Tujuan dari penelitian ini adalah untuk menganalisi kondisi karang serta kelimpahan clownfish di Pulau Gili Labak, Sumenep. Penelitian ini dilakukan pada bulan oktober 2021 pada 4 stasiun pengamatan di Perairan Pulau Gili Labak, Sumenep. Metode yang digunakan untuk mengambil data kondisi terumbu karang yaitu menggunakan belt transek dengan panjang 50 m sejajar garis pantai untuk pengambilan data kelimpahan clownfish menggunakan metode UVC (underwater visual sensus) dan untuk pengambilan data kecerahan, salinitas, suhu dan kecepatan arus menggunakan data in situ (langsung). Hasil yang didapat dari penelitian ini hubungan kondisi terumbu karang dan clownfish yaitu korelasi bernilai positif dengan koefisien determinasi (R²) = 0,8048. Hubungan antara kondisi terumbu karang dan kelimpahan anemon laut yaitu korelasi bernilai negatif dengan nilai koefisien determinasi (R²) = 0,2049.
Analisis Marketing Margin Dan Farmer’s Share Ikan Asin di Kecamatan Paiton Kabupaten Probolinggo
Authors: Jazila Ismi
Published: May 2023

Tujuan dari penelitian ini adalah untuk: (1) Menganalisis saluran pemasaran, (2) menganalisis margin pemasaran dan farmer’s share ikan asin di Kecamatan Paiton Kabupaten Probolinggo. Penelitian ini dilakukan di Desa Sumber Anyar, Kecamatan Paiton, Kabupaten Probolinggo, Jawa Timur. Data yang digunakan dalam penelitian ini adalah data primer dan data sekunder. Penentuan sampel dalam penelitian ini menggunakan dua metode yaitu purposive sampling dan sensus sampling. Desa sample ditentukan dengan teknik purposive sampling dimana desa Karang Anyar merupakan salah satu desa sentra usaha ikan asin di Probolinggo. Penentuan sampel menggunakan sensus sampling. Terdapat 5 pengusaha ikan asin yang menjadi responden di desa Karang Anyar dengan scala usaha yang berbeda beda. Hasil dari penelitian menunjukkan bahwa terdapat 2 saluran pemasaran di lokasi penelitian yaitu saluran 1,  produsen – pedagang besar – konsumen akhir. Saluran 2. Produsen, pedagang pengumpul, pedagang pengecer, konsumen akhir; margin pemesaran terbesar terjadi pada saluran pemasaran 2 yaitu Rp 23.000 per kg. Hal tersebut karena lembaga pemasaran yang terlibat lebih banyak. Farmer’s share terbesar / bagian terbesar yang diterima produsen ikan asin terjadi pada saluran 1. Yaitu 52 %. Sedangkan nilai farmer’s share saluran 2 adalah 47 %. Sehingga dapat disimpulkan saluran pemasaran yang paling efisien terjadi pada saluran 2.
Derecho de participación de niños, niñas y adolescentes en procesos de mediación por litigios familiares
Authors: Gil-Osuna Bartolomé
Published: May 2023

El objetivo general de la presente investigación fue determinar el derecho de participación de niños, niñas y adolescentes en procesos de mediación por litigios familiares. Se desarrolló desde el paradigma cuantitativo, se enmarcó a partir de un diseño documental-bibliográfico. Para lo cual se examinó la legislación ecuatoriana y doctrina nacional que ha tratado el tema, según varias perspectivas, haciendo uso de artículos científicos, tesis, leyes y normas. Se aplicó una encuesta que fue realizada en la ciudad de Ibarra, Provincia de Imbabura, a miembros de diversas familias que recurrieron al Centro de Resolución de Conflictos de la Pontificia Universidad Católica del Ecuador. Se concluye que, es pertinente desarrollar in extenso en investigaciones futuras el hecho de desconocer los derechos de los niños, niñas y adolescentes por criterios adultocentristas que se inician en el seno familiar.
Asociación entre violencia íntima de pareja contra la mujer y desnutrición crónica entre los hijos menores de 5 años: Análisis de la Encuesta Demográfica y de Salud Familiar del 2020 en Perú
Authors: Arrascue Joaquín , Oyola Almendra , Chapilliquen Daniela , Villanueva Daphne , Zapata Ever , Romaní-Romaní Franco
Published: May 2023

Introducción: La asociación entre violencia íntima de pareja contra la mujer y la desnutrición crónica en los hijos no ha sido claramente establecida. En diversos marcos conceptuales que explican la desnutrición infantil, no se considera la violencia doméstica como una determinante. Objetivo: Evaluar la asociación entre violencia íntima de pareja contra la mujer y la desnutrición crónica en los hijos de 5 años o menos. Material y métodos: Realizamos un estudio de fuentes secundarias basada en la Encuesta Demográfica y de Salud Familiar 2020 del Perú. Estimamos la razón de momios cruda y ajustada con una regresión logística binaria que consideró como exposición a la violencia íntima de pareja y variable dependiente a la desnutrición crónica, además incluimos 16 covariables de interés seleccionadas a partir de la literatura pertinente. Resultados: Incluimos los datos de 8980 mujeres y sus respectivos hijos. La prevalencia de desnutrición crónica en los hijos de 5 años o menos fue de 10,7% (IC95%: 9,8 a 11,7). No encontramos asociación entre la desnutrición crónica en los hijos y la violencia emocional (ORa: 0,98, IC95%: 0,72 a 1,32), la física severa (ORa:1,02, IC95%: 0,62 a 1,68), y sexual (ORa: 0,94, IC95%: 0,50 a 1,77) contra las madres. Conclusiones: Estos resultados suman a la evidencia que apoya la ausencia de asociación entre los tres tipos de violencia íntima de pareja como factores de riesgo de la desnutrición crónica en los hijos de 5 años o menos y ponen de manifiesto la importancia de otras variables como el nivel educativo de la madre.
Hiperglicemia asociada a mortalidad en pacientes de una unidad de cuidados intensivos pediátricos
Authors: Castañeda Alejandra , Rojas-Vivanco Paola , Chávez-Valdivia Alexi , Valdivia-Tapia María del Carmen , Yhuri Carreazo Nilton
Published: May 2023

Objetivo: Determinar la asociación entre los valores de glicemia y mortalidad en la Unidad de Cuidados Intensivos Pediátricos (UCIP) del Hospital de Emergencias Pediátricas. El estudio: Estudio de cohorte retrospectivo, en pacientes pediátricos entre 1 mes y 18 años; hospitalizados en la UCIP del Hospital de Emergencias Pediátricas por más de 48 horas, durante el año 2016. Hallazgos: Se incluyeron 184 pacientes. La mediana de edad fue de 33.5 meses, la mortalidad fue de 11.54%. El análisis ajustado demostró que glucosa máxima en 24 horas y valor en la escala de Pediatric Index of Mortality 2 (PIM2) podrían presentarse como factores de riesgo para mortalidad, a diferencia de sexo, edad y valor de escala de Glasgow que se presentaron como factores protectores. Conclusión: En la serie evaluada se encontró asociación entre el valor de glucosa máxima en las primeras 24 horas y mortalidad en la UCIP. Es preciso realizar estudios prospectivos para evaluar dicha asociación
Isquemia mesentérica aguda asociada a Covid-19: serie de casos
Authors: Tafur-Hoyos Brenda Aurora
Published: May 2023

Introducción: Los pacientes con Covid-19 pueden presentar complicaciones serias como: tromboembolia pulmonar y la isquemia mesentérica aguda (IMA). Estos eventos trombóticos son más frecuentes en el contexto de la pandemia debido al estado de hiperinflamación e hipercoagulabilidad transitoria con la que cursan los pacientes. Reporte de casos: Se describe casos de Covid-19 que cursaron con IMA en el norte de Perú. Son dos pacientes hombres de 48 y 67 años, con una evolución subaguda cursaban con síntomas respiratorios sin embargo en días posteriores sus cuadros empeoraron cursando con dolor abdominal, niveles elevados de dímero D y alteraciones de la coagulación. Ambos presentaron IMA sin embargo, no se sospechó de dicho diagnóstico sino hasta ser intervenidos quirúrgicamente. Pese a que el segundo paciente uso enoxaparina y se le intervino dentro de las 24horas su desenlace fue fatal. Conclusión: Ante un paciente con Covid-19 y síntomas gastrointestinales atípicos, se debe considerar esta enfermedad en el diagnóstico. Es importante saber reconocerlo tempranamente.
Parámetros hematológicos y laboratoriales tempranos asociados con la mortalidad por COVID-19 en una población amazónica del Perú
Authors: Iglesias-Osores Sebastián , Rafael-Heredia Arturo , Rojas-Tello Eric R , Ortiz-Uribe Washington A , Leveau-Bartra Walter R , Leveau-Bartra Orison A , Córdova-Rojas Lizbeth M , Colmenares-Mayanga Wagner , Failoc-Rojas Virgilio E
Published: May 2023

COVID-19 tiene un impacto significativo en el sistema hematopoyético y la hemostasia. La leucocitosis, la linfopenia y la trombocitopenia se asocian con una mayor gravedad e incluso la muerte en los casos de COVID-19. Objetivo: examinar los resultados de laboratorio de pacientes con COVID-19 de un hospital de la Amazonía peruana y su pronóstico clínico. Material y métodos: Se realizó un estudio transversal analítico cuyo propósito fue identificar las pruebas de laboratorio de pacientes con COVID-19 y mortalidad en un hospital de Ucayali, Perú durante el periodo del 13 de marzo al 9 de mayo del 2020, seleccionando un total de 127 con COVID-19. Se describió la media y la desviación estándar para edad, leucocitos, neutrófilos, plaquetas, RDW-SD; mediana y rango intercuartílico para las variables linfocito, RN/L, fibrinógeno, PCR, dímero D, DHL, hematocrito, monocitos, eosinófilos. Resultados: No se observaron diferencias en esta población en cuanto a muerte y sexo (OR: 1,31; IC 95% 0,92 a 1,87), sin embargo, se observó que, por cada aumento de un año, la probabilidad de muerte aumentaba un 4% (RP: 1,04). , IC del 95%: 1,03 a 1,05). El análisis de RIR (Razón de incidencia de riesgos) para las variables numéricas mostró resultados fuertemente asociados con valores hematológicos como Leucocitos (escala de 2500 unidades) (RRI: 1.08, 95% CI 1.03 a 1.13), neutrófilos (escala de 2500 unidades) (RRI: 1.08; IC 95% 1.03 a 1.13), por el contrario, se observa que al aumento de 1000 unidades en linfocitos, la probabilidad de morir disminuyó en un 48% (TIR: 0.52; IC 95% 0.38 a 071). Conclusiones: Parámetros tales como los leucocitos, los neutrófilos y el dímero D fueron estadísticamente mucho más altos en los pacientes que fallecieron.
Dosis de vacuna aplicada contra COVID-19 y recuperación del paciente atendido en UCI-COVID. Hospitales de contingencia EsSalud-Lambayeque. Diciembre 2021-febrero 2022.
Authors: Pecsén Monteza José Enrique , Pecsén Monteza Valentín , Romero Paredes Rolando , Carranza Lent Fernando
Published: May 2023

Introducción: La vacunación contra la COVID-19 a demostrado disminuir el riesgo de morbimortalidad en la forma grave de COVID y hospitalización en los pacientes susceptibles. Objetivo: Determinar si existe relación entre la cantidad de dosis de vacuna aplicada contra COVID-19 y la recuperación del paciente atendido en UCI de Hospitales de Contingencia de EsSalud-Lambayeque entre diciembre 2021 a febrero del 2022 Material y métodos: Se planteó un estudio descriptivo, transversal, correlacional y retrospectivo; en una muestra de 94 pacientes hospitalizados en la UCI de los Hospitales Luis Heysen Inchaustegui y Almanzor Aguinaga Asenjo, seleccionados aleatoriamente. Utilizando ficha de recolección de datos validada por expertos se obtuvo información de las historias clínicas de la red informática institucional, manteniendo la confidencialidad y normas éticas. Para el análisis se utilizó porcentajes, frecuencias y Chi Cuadrada para relación de variables categóricas. Resultados: Se encontró 60,64% sexo masculino, edad promedio de 64,38 +/-13,65 años, el 53,19% tenía una comorbilidad, el 21,27% dos a más, destacando la Hipertensión Arterial y Diabetes Mellitus. El 35,11% no tenía vacunas, 34,04% segunda dosis, 23,40% tercera dosis y 7,45% primera dosis. En la condición de alta de UCI el 43,62% se recuperó. La recuperación del paciente con primera dosis fue de 57,14% (p<0,008), segunda dosis en 65,63% (p<0,00002) y tercera dosis 50% (p<0,003) Conclusiones: Si existe relación significativa entre la cantidad de dosis de vacuna COVID-19 y la recuperación del paciente en UCI, mayor prevalencia del sexo masculino, adulto mayor y comorbilidades como Hipertensión arterial y Diabetes mellitus.
Narrativas del donante de plasma convaleciente en EsSalud: motivaciones, miedos, expectativas y experiencias
Authors: Soto Becerra Percy , Matassini Eyzaguirre Silvana M. , Villanueva Yapa Christian , Chunga Chunga Ausberto , Sagastegui Soto Arturo , Neyra Vera Ibeth Melania , Soto Ordoñez Suly , Guillermo Román Martina , Oyanguren Miranda Martin , Soto-Becerra Percy , Hurtado Roca Leda Yamileé , Maguiña Jorge L. , Araujo-Castillo Roger Vladimir
Published: May 2023

Objetivos: Explorar, desde las narrativas de la población de donantes de plasma convaleciente en un ensayo clínico, las experiencias en el proceso de donación de sangre. Material y Métodos: Se realizó un estudio cualitativo con diseño fenomenológico. La investigación se llevó a cabo en un hospital de la seguridad social del Perú aplicándose entrevistas semiestructuradas a profundidad. Resultados: Se entrevistó a once donantes de plasma convaleciente. Se identificó que las principales motivaciones de los donantes fueron tanto el poder contribuir a la investigación nacional como, apoyar a pacientes afectados por la COVID-19. Los principales miedos se centran en el posible riesgo de contagio dentro del hospital. Por otro lado, los donantes resaltaron la atención y acompañamiento del personal de salud en el proceso. Las principales expectativas y sugerencias apuntan hacia una mayor difusión de las campañas de donación de sangre en general, con especial énfasis en el tema de seguridad, la mejora en el tiempo del procedimiento de donación (en el caso de la donación de plasma convaleciente, desde el enrolamiento hasta la extracción de plasma convaleciente) y, la implementación de espacios amigables para incentivar las futuras campañas de donación de sangre en  general. Conclusiones: Las experiencias de los donantes de plasma convaleciente fueron positivas. Sin embargo, aún hay mejoras que realizar a nivel de procesos e infraestructuras para asegurar campañas exitosas de donación de sangre futuras.
Modernización de la Gestión Hospitalaria En Instituciones Prestadoras de Salud
Authors: Vásquez Sáenz Oscar Augusto , Montenegro Camacho Luis Arturo
Published: May 2023

Se realizó una revisión breve con aproximación teórica a la actual organización hospitalaria y su modernización. Se muestra un enfoque de la actual organización hospitalaria. Además, se presenta el procedimiento y las particularidades de los rumbos del sector hospitalario; pudiendo posteriormente analizar los mecanismos de modernización a entes relacionados con el bienestar de la población y poder hacer uso de manera óptima de las metodologías de dirección. Los factores que motivan el cambio, por ser las organizaciones con mayor complicación en su área en específica; siendo así que sus actividades que varían en diversos sectores de acuerdo a lo especificado en sus lineamientos puedan ser entendidas de manera clara, aun cuando se consideren las peculiaridades de cada organización.
Platelet-Rich Plasma on Ankle Sprains – Efficacy on Pain Reduction and Shorter Return to Play: A Systematic Review of Available Randomized Control Trials
Authors: Milo Anne Marie M , Braganza Carmelo L
Published: May 2023

Background: The role of platelet-rich plasma (PRP) has been widely studied, but only recently did trials emerge that probed into its potential role in ankle sprains. With the limited available literature, most of the trials results showed that it might have a role in faster healing and pain reduction. Objectives: The purpose of this review is to summarize available studies on ankle sprains in order to identify if there is good initial evidence of its role on return to play (RTP) among active individuals as well as pain reduction. It is also to identify if results were consistent among studies. Methodology: A systematic search of available literature in online databases was done to compare results about outcome measures on pain score and RTP. Included studies are those with a population of 18 years and above treated with PRP with or without post-procedural immobilization. Outcome scorings that assessed pain as a parameter was also included. Results: Three randomized controlled trials and two prospective studies were identified. Results showed an average of 8 weeks to RTP (p-value - 0.006) with decreased pain in ankle sprains treated with PRP and functional therapy. Limitation: Only one randomized controlled trial (RCT) compared PRP with a placebo and a small population of all studies made available. More comparable RCTs are needed to strengthen results of the studies. Conclusion: The use of PRP on ankle sprains may have a potential role in shorter time to RTP and pain reduction. Key words: Ankle Sprains, Lateral Ankle Sprains, Platelet-rich Plasma PRP