bluuebunny/crossref_metadata_2025 huggingface dataset:
Formulation and Evaluation of Analgesic and Anti-Microbial Transdermal Patch of an Herbal Drug
Authors: Patil Aakash , Patil Abhishek , Bongale. Aishwarya
Published: December 2024

An Analgesic and Antimicrobial
formulation was formulated into transdermal patch
by using herbal drugs so as to give higher onset of
action and quick relief over small cuts, minor
wound injury with pain as well as to provide better
patient compliance. Herbal drugs were identified,
Collected and extracted by using appropriate
pharmaceutical methods and Processes. Different
trials were taken to optimize the ratio of diluents
and to select appropriate Polymers,
Plasticizers/Binders, solvents and their
concentrations. The formulations were evaluated
for Physical parameters as per official
pharmacopeia. The Preformulation and
Formulation results of optimized Formulation
exhibited best results in all evaluation tests.
The Significance of Real-World Evidence in Pharmacovigilance: Enhancing the Drug Safety Monitoring
Authors: Raysahab Pandey Aditya , Dubey Devansh , marchande Sushant , Subhash Gaikwad Vishvajit , Gadhave. Nayana Sharad
Published: December 2024

Pharmacovigilance is focused on
examining the safety of pharmaceuticals after they
are marketed. Traditionally, it relies on data from
clinical trials and mechanisms for impulsive
reporting to determine adverse drug reactions
(ADRs). Although, the scope of clinical trials is
frequently limited, excluding certain population
analysis and realistic conditions of the world [1].
Regardless of these disadvantages, Real World
Evidence (RWE) enhances a useful tool that uses
data from sources like patient registries, insurance
claims, and electronic health records (EHRs) to
recognize adverse drug reactions (ADRs) and
contribute to enhanced comprehension of
medication safety in variant populations. Firstly,
Pharmacovigilance is the science of identifying,
evaluating, and averting drug side effects, and is
crucial to assure the reliability of pharmaceutical
products after they are distributed in the market [2]
The new challenges of agricultural policy: new actors and redefined development paradigms
Authors: Del Giudice Teresa
Published: December 2024

The role of the agricultural sector has had to evolve as our global social economic system has been changed by drivers such as climate change, demographics, ecosystem depletion, changes in dietary patterns and rising food demand. A key characteristic of 21st century agriculture is the reaffirmation of its primary function: producing sustainable food for a growing global population living in increasing inequality and political instability. However, the role of agriculture also goes beyond feeding the planet; it increasingly involves maintaining the environment. Meeting these challenges will require significant changes in the sector’s organisational and operational boundaries and bold intervention from the research community and public sector alike to generate new knowledge and innovation systems. This paper aims to describe and analyse, where possible, the changes this transition will entail in terms of stakeholders, policy interventions, governance, development models and, finally, the role research should play in future scenarios.
Раздаток. Базовая модель России в новой реальности
Authors: Бессонова О.Э.
Published: December 2024

Монография выполнена в рамках экономико-социологического направления и состоит из трех частей. В первой части представлена авторская интегрально-институциональная парадигма на основе синтеза теории раздаточной экономики с классическими подходами и современными концепциями. На ее основе показан реальный, а не воображаемый разными идеологическими направлениями, путь России.
Во второй части последовательно, начиная с IX века и по настоящее время, анализируются этапы развития базовой экономической модели России. Эволюция модели раздаточного типа и анализ современного положения России проводится с использованием обширных исторических фактов, пропущенных через методологическую схему новой парадигмы. Ключом к базовой модели России на мезоуровне стал жилищный раздаток, показывающий возможности новой парадигмы в практическом плане.
В третьей части раскрывается смысл «новой реальности», в которой будут созданы условия для эффективного развития социального государства. Ее чертами могут стать экономика контрактного раздатка, идеология солидаризма и активное гражданское участие в создании справедливого общества. Для этого обосновывается необходимость специфически российского «нового курса» для преодоления кризиса экономической модели квазирынка.
A Correlation Study: The Influence of Service Quality to Satisfaction at Fitness Facilities in Sleman Regency, Yogyakarta
Authors: Salsabila Nisrina Aulia , Nasrulloh Ahmad , Prabowo Trisnar Adi , Chandrika Wilhelmus Merdyto Rhino
Published: December 2024

The purpose of this study is to explore the relationship between service quality and customer satisfaction at fitness facilities. This type of research is quantitative with a correlation method, sample selection using accidental sampling consisting of: 1) 64 respondents who train at the gym, 2) 114 respondents who train at a fitness studio (type of training: training zumba, pilates, yoga, calisthenics, poundfit, TRX, body combat), 3) 82 respondents who train at a swimming pool or sports field (type of training: soccer, fun football, futsal, badminton, basketball, tennis). The questionnaire on the indicators in Service Quality is Tangibility, Reliability, Responsiveness, Assurance, Empathy, then the indicators in Satisfaction are Complaints and Suggestions System, Comfort and Safety, Communication. The results of this study are that Service Quality has a positive effect on Satisfaction 0.000, then the correlation value is 1) facilities in the gym r = 0.636, 2) facilities in the fitness studio r = 0.687, 3) facilities in the swimming pool or sports field r = 0.504. The conclusion of this study confirms the importance of service quality in improving customer satisfaction in fitness facilities. For further research, it is recommended that the data collection time be extended. Then, broader research with a larger population is also needed to obtain more representative results.
Efficacy of PHILOS Plates in Managing Osteoporotic Proximal Humerus Fractures: A Long-Term Functional Outcome Study
Authors: Beg Dr. Mirza Osman , Azad Dr. Abul Kalam , Rahman Dr. Md. Munzur
Published: December 2024

Background: Osteoporotic proximal humerus fractures pose significant challenges due to reduced bone quality and healing potential. PHILOS plates offer angular stability, but long-term prospective outcome studies are limited. Objective: To prospectively evaluate the efficacy of PHILOS plates in managing osteoporotic proximal humerus fractures, focusing on functional recovery, complication rates, and patient satisfaction. Methods: This prospective study was conducted at the Department of Orthopaedic Surgery, North East Medical College, Sylhet, also with multicentered study from June 2022 to July 2024, involving 358 patients with osteoporotic proximal humerus fractures. Patients underwent open reduction and internal fixation using PHILOS plates. Functional outcomes were assessed using the Constant-Murley Score (CMS) and DASH score at 6, 12, and 18 months postoperatively. Complications, including screw perforation and avascular necrosis, were systematically recorded. Data analysis included mean score changes, percentages, and ANOVA for repeated measures. Results: The study reported a 94% follow-up rate. At 18 months, 83.5% of patients achieved good to excellent outcomes based on CMS. The mean CMS improved from 30.2 preoperatively to 76.8 at 6 months, 81.4 at 12 months, and 83.9 at 18 months (p < 0.001). The DASH score significantly decreased from 58.1 to 18.5 over 18 months. Complication rates included screw perforation in 6.7%, avascular necrosis in 5.3%, and hardware failure in 4.2%. Patients <70 years showed a mean CMS of 86.1 compared to 77.5 in older patients (p = 0.02). Conclusion: PHILOS plates provide reliable fixation for osteoporotic proximal humerus fractures, yielding excellent functional outcomes and manageable complication rates in a prospective setting.
Efficacy of Perioperative Oral Antibiotics in the Prevention of Acute Infective Endophthalmitis after SICS
Authors: Akanda Dr. Md. Ameenur Rashid , Khuda Dr. Md. Rahmet-E-
Published: December 2024

Objective: The objective of this study to evaluate the efficacy of perioperative oral antibiotics in the prevention of acute infective endophthalmitis (IE) after cataract surgery. Methods: This prospective study of patients undergoing uncomplicated SICS was conducted. Group A was given post-op oral ciprofloxacin for five days, whereas Group B was not. Both groups received 5% povidone-iodine (PVI) preparation for three minutes in the conjunctival cul-de-sac preoperatively as prophylaxis. The minimum post-operative follow-up period was six weeks. Results: Out of 1856 patients, 896 (48.27%) were included in Group A, and 960 (51.72%) were included in Group B. No significant difference in anterior chamber (AC) reaction was found on day 1 (p = 0.69), day 14 (p = 0.06), or day 42 (p = 0.1). One patient developed acute post-operative infective endophthalmitis (0.04%) and one patients developed toxic anterior segment syndrome (TASS) from Group A. The non-oral antibiotic group had no serious complications. Conclusions: Perioperative oral antibiotic use in routine clinical practice is not recommended for the prevention of acute post-operative infective endophthalmitis. Pre-operative conjunctival PVI 5% for five minute was proven to be effective prophylactic measures in our study.
Analysis of Adherences and Effectiveness in Tuberculosis Patients at a Hospital in West Java Province in Indonesia
Authors: Syahrina Nadira Alvi , W Siti Pandanwangi, T. , Karsidin Bambang , Madhiyyah Cut Ainul , Sumari Sumari
Published: December 2024

Tuberculosis (TB) TB disease is still a health threat both worldwide and in Indonesia. Cases of TB disease in Majalengka District continued to increase in 2020, with as many as 9,497 cases; in 2021, as many as 12,692 cases; and in 2022, a significant increase of 21,956 cases. This study aims to determine patient characteristics, level of adherence, and effectiveness of TB treatment, as well as the relationship between adherence and effectiveness of TB treatment in a hospital in Majalengka District in West Java. The research method used was descriptive observational analysis with retrospective data collection based on TB patient treatment cards. Adherence data was collected by completing the MMAS-8 questionnaire, and effectiveness data were collected by recording sputum examination results using SITB software. The sample is the total population according to the criteria. The technique used to draw this sample was total sampling, namely the total number of TB patients in a Hospital from November 2023 to April 2024, which was 45 patients. Data analysis was done using the Chi-square test. A total of 95.6% had a high level of adherence, and 4.4% of patients had moderate adherence. The efficacy of TB treatment was 100%, with 97.8% cured status and 2.2% complete treatment. There was a significant relationship between adherence and TB treatment effectiveness, with a p-value of 0.044 (sig<0.05).
Formulation and Characterization of Invasomes Gel of Bacitracin for Effective Treatment of Topical Disease
Authors: Motwani Aakanksha , Dubey B. K. , Basedia Deepak Kumar , Patel Mukesh Kumar , Shah Sunil Kumar , Thakur Vivek Singh
Published: December 2024

Topical drug administration is a localized drug delivery system anywhere in the body through Optimized invasomal formulation was sealed in 10ml glass vial and stored at refrigeration temperature (4 - 8°C) and room temperature for one month. Entrapment efficiency, physical appearance was determined at regular intervals ophthalmic, rectal, vaginal and skin as topical routes. Skin is one of the most readily accessible organs on human body for topical administration and is main route of topical drug delivery system. Invasomes are considered an inventive drug delivery system for the transdermal route. It improves the permeability of drugs across the skin layers which limits the absorption of poorly permeated drugs. It is also used for enhancing the efficacy and duration of action for drugs that had first-pass metabolism in the liver requires multiple daily doses. Invasomes contain unique components (Phospholipids, terpenes and ethanol) that act as safe and effective drug permeation enhancers across skin layer. Bacitracin is a cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections. Bacitracin (200mg) was loaded in to invasomes by mechanical dispersion technique using Phospholipon 90H, terpene (Limonene) and ethanol, The optimized Bacitracin -loaded invasomes was incorporated into carbopol 934p (0.5 to 2%) solution to get a hydrogel for improving convenience in superficial application. FT-IR studies revealed no interaction between the drug and excipients. The formulated hydrogel formulation was evaluated with parameter pH, viscosity, gel strength, drug content, spreadability, in-vitro release test, washability, extrudability study and stability studies. The formulation IG-2 showed a drug content of 98.74% and drug release of 99.85% in 12hrs, which contains carbopol 934p concentration 2%w/w. The present work also focuses on making the formulation more pharmaceutically acceptable.
Improving Success Rates and Reducing Complications in Intravenous Cannulation: Knowledge and Practice on Peripheral Intravenous Catheterisation among Nurses of Armed Forces Hospital-King Abdulaziz Air Base in Dhahran, Saudi Arabia
Authors: AbuBakar Daelia , Otaibi Shrooq Al , Omairi Salhah Al
Published: December 2024

This study systematically examines the knowledge and practices of Peripheral Intravenous Catheterization (PIVC) among nursing professionals at the Armed Forces Hospital in King Abdulaziz Air Base (AFH-KAAB) in Dhahran, Saudi Arabia. The primary objective is enhancing success rates and minimising complications associated with intravenous cannulation through improved training methodologies. Employing a mixed-methods approach, this research integrates qualitative insights from clinical practice and focus group discussions with quantitative data analysis. Data were collected using a self-administered survey and analysed using SPSS Version 29. The survey encompassed socio-demographic information, sources of knowledge concerning PIVC, and specific practices associated with PIVC. The findings reveal that socio-demographic factors significantly impact knowledge and practice levels, underscoring the need for tailored educational resources. The study concludes that implementing targeted interventions to enhance nurses’ knowledge and skills in PIVC can significantly improve patient safety, increase success rates, and lead to more favourable healthcare outcomes. These findings provide critical insights for developing customized training programs and educational initiatives to elevate nurses’ competency and proficiency in PIVC. Ultimately, these efforts contribute to achieving zero harm in intravenous care and optimising healthcare quality by reducing patient harm.
Detection of Antimicrobial Activity of Acacia nilotica Extract on Gram-Negative Bacteria Isolated from Clinical Specimens in Shendi Town, Sudan
Authors: Abdelgader Leila Mohamed A. , Zain Tagreid Hassan Khaleid M. , Mahjaf Ghanem Mohammed
Published: December 2024

Background: In the underdeveloped world, microbial infections constitute a serious public health concern. About half of all deaths in tropical nations are thought to be caused by infectious diseases. In addition, some well-known pathogens have assumed new epidemiologic importance by acquiring antimicrobial resistance. Some plants are known as medicinal because they contain active substances that cause specific reactions relating to the cure of human disease. Acacia nilotica, commonly known in Sudan as Garad or Sunt, has many medicinal uses. Objectives: This study used the agar diffusion method to study the antibacterial activity of the different concentrations of ethanolic extract of the medicinal plant Acacia nilotica pods against selected gram-negative bacteria. Methodology: A cross-sectional study was done in Shendi Town, River Nile State, at the microbiology laboratory at Shendi University. Eighty-five wound swabs and urine specimens were collected from patients with symptoms of urinary tract infection and wound infection who attended Shendi Teaching Hospital and Almek Nimir University Hospital from February to March 2023; bacteria were isolated and identified using colonial morphology, Gram stain, and biochemical tests. Using the agar well diffusion method, we tested the Acacia nilotica extract at 100%, 50%, 25%, and 12.5% w/v concentrations. Results: This study found infection was persistent in patients aged 26–34. Escherichia coli was a primary isolate. According to gender, out of 85 specimens, 26 (30.6%) were males, whereas 59 (69.4%) were females. The ethanolic extract of Acacia nilotica pods was screened for their antimicrobial activity against clinical isolates of Escherichia coli, K. pneumoniae, Pseudomonas aeruginosa, Enterobacter, Citrobacter, Serratia, Providencia, and Proteus vulgaris. The antimicrobial effect of the extract was compared with the standard drugs. Crude extracts of Acacia nilotica inhibited the growth of various bacteria and showed its broad spectrum antimicrobial potential, which may be employed in managing microbial infections. Conclusion: The fruits of Acacia nilotica were the subject of these investigations, demonstrating its potent in vitro activity against clinically isolated bacteria and its potential as a treatment for various bacterial and viral infections.
Formation of residual stresses during vibroabrasive machining of parts
Authors:   Dimov YU.V.
Published: December 2024

The value of work hardening and residual stresses in the surface layer of a part after vibroabrasive machining are investigated. Dependences of the change in residual stresses on the parameters of the machining mode are obtained: amplitude and frequency of vibrations, mass and speed of granules, machining time.

Keywords
vibroabrasive machining, abrasive granule, residual stresses
Dimov-Ura@yandex.ru
Formation of grips of an anthropomorphic bionic hand
Authors:   Bezyazychny V.F. Yudin A.V. Eliseichev E.A. Pankratov M.V. Mihaylov V.V.
Published: December 2024

The formation of grips of an anthropomorphic bionic hand using numerical methods for minimizing of the error function based on a mathematical model of the hand is considered. A grip quality criterion is proposed — the sum of the distances from the grasped object to the structural elements of the phalanges of the fingers. The effectiveness of the proposed method is verified by modeling a solid model of the hand in Matlab Simulink.

Keywords
anthropomorphic bionic hand, grip, quality, multidimensional minimization, modeling, Solidworks, Matlab Simulink
EvgenijEliseichev@yandex.ru
Parameters of the stress-strain state of the surface layer of parts at shot peening hardening
Authors:   Shin I.G. Maksudov R.H. Muminov M.R. Nazarov S.R.
Published: December 2024

The process of shot peening hardening and the stress-strain state of parts that have undergone strain hardening are studied. The problem of contact interaction at ball indentation into an elastic half-space is solved.

Keywords
shot peening hardening, stress state, ball, distributed load, stress, plastic imprint, speed, hardness, deformation, static force
saxrobn84@gmail.com
Determination of the power of the embedded heater at the cooling stage when welding polyethylene pipes in conditions of low temperatures
Authors:   Starostin N.P. Ammosova O.A.
Published: December 2024

A method is proposed for determination of the power of an embedded heater when welding of polyethylene pipes at low temperatures based on solving of the inverse control problem. The possibility of selection of weight functions and setting of temperatures to determine the heater power that provides the dynamics of the crystallization completion boundary in the heat-affected zone, corresponding to welding under normal conditions, is shown.

Keywords
polyethylene pipes, welding, low temperature, embedded heater
ammosova_o@mail.ru
Atomic dislocation approach to assessment of strength and crack resistance of hard alloys and coatings at fracture
Authors:   Kabaldin Yu.G. Bashkov A.A.
Published: December 2024

The fracture toughness and dislocation structure of hard alloys and wear-resistant nanostructured coatings are studied. An assessment of the strength of structural elements of hard alloys and recommendations on the choice of hard alloy and nanostructured coating for high-performance machining are given.

Keywords
hard alloy, dislocation structure of carbides, strength of structural elements, wear-resistant coating
uru.40@mail.ru , kicliu@mail.ru
Aspects of import substitution of abrasive tools at machine-building enterprises
Authors:   SHumyacher V.M. Kryukov S.A. Morozova N.A. Grebenyuk N.S.
Published: December 2024

The work of domestic machine-building plants operating under the conditions of sanctions imposed on the import of a number of technological equipment is analyzed. Recommendations are developed for import substitution of abrasive and diamond tools due to the leaving of some companies supplying these products from the Russian market.

Keywords
mechanical engineering, grinding, abrasive tools, import substitution
ne5942@yandex.ru
Elastic-plastic state of rods under spatial loading, taking into account hardening-softening and damageability
Authors:   Olimov M. Ismoilov SH.M. Abdujalilov S.M. Studenkova D.V.
Published: December 2024

The development of a mathematical model of a rod for studying of the displacements of points under the simultaneous action of longitudinal, transverse and torsional forces is considered. The equilibrium equations for a rod under spatially variable elastoplastic loading and unloading are obtained. The stress-strain state of the rod is studied based on the generalized Masing principle.

Keywords
space, rod, loading, unloading, deformation, intensity, approximation, running, iteration, mathematical model, hardening, softening, damageability, equilibrium
MOlimov5152@gmail.com, sodiq.abdujalilov1992@gmail.com, studenkova.d@gmail.com, shohsoft@gmail.com
A new method of production of highly porous powder products
Authors:   Mamedov A.T. Babaev A.I. Ismailov N.S. Guseynov M.CH. Musurzaeva B.B.
Published: December 2024

A method for forming of highly porous powder products based on the principle of mixture blowing compaction of a powder charge is considered. The change in the speed of the powder-air jet during the filling of a briquette mold with bottom ventilation is studied depending on the duration of inflation with compressed air. The advantages of this method of forming of highly porous briquettes in comparison with cold pressing are shown. It is shown that this method of molding with subsequent sintering can produce highly porous large-sized products and complex structures.

Keywords
highly porous product, mixture blowing machine, porosity, compressed air, briquette, powder-air jet, kinetic energy
ariff-1947@mail.ru, aqil.babayev@aztu.edu.az, nizism@mail.ru, muxtar.53@mail.ru, musurzayeva71@mail.ru
Automation of tensioning of saw blades with circular translational motion in new type equipment
Authors:   Blokhin M.A. Dyimchakov I.I. SHein A.P. Emelyanov D.D.
Published: December 2024

The advantages of the developed woodworking complex are considered. The problem of operational controlled tension of saw blades in saw modules of sawmilling equipment has been solved. The scheme of a self-locking device for lifting the upper shaft of the saw block, which simultaneously provides tension of the blades in six saw modules, is implemented. The parameters of microelectromotors and the reliability of mechanisms providing tension are determined.

Keywords
saw module, saw block, worm pair, contact voltages
hornet10@yandex.ru
Diagnostics of cutting ability of an abrasive tool using acoustic emission control
Authors:   Mitrofanov A.P. Rastegaev I.A. Jitnikov K.O.
Published: December 2024

The inverse problem of positions of a six-moving hybrid parallel mechanism with a 3-(3-PRR)PS structure with kinematic redundancy is considered. Each kinematic chain of the mechanism includes a flat 3-PRR mechanism of a parallel structure. An analytical solution of the problem under consideration is obtained, and an example of calculation is given.

Keywords
parallel structure manipulator, inverse problem of positions, kinematics, hybrid mechanism
a.mitrofanov@stankin.ru, rastigaev@yandex.ru
Prevalência de Cardiopatia Fetal em Gestantes Encaminhadas para Serviço Especializado Devido a Alterações Cardíacas no Ultrassom Morfológico
Authors: Michael Andressa Pinto , Soares Marcelo França , Foresti Roque Antonio , Rodrigues Marco Otilio Duarte , Witkowski Sandra Mara
Published: December 2024

Fundamento: As Cardiopatias Congênitas (CC) são malformações do coração e/ou dos grandes vasos, sendo a terceira
causa de óbito neonatal. Podem ser identificadas intraútero pela Ultrassonografia Morfológica (USGM) e confirmadas pelo Ecocardiograma Fetal (ECF).

Objetivo: O estudo visa observar se as cardiopatias detectadas no USGM das gestantes assistidas pelo centro de referência materno de uma cidade do sul do Brasil, são confirmadas pelo ECF.

Métodos: Estudo observacional, descritivo e retrospectivo, realizado de março de 2019 a janeiro de 2023, analisou gestantes da rede pública, atendidas através do Sistema Único de Saúde (SUS), em centro de referência materno de uma cidade do sul do Brasil, com alterações cardíacas na USGM e confirmação por ECF.

Resultados: Entre as 37 gestantes com suspeita de alteração cardíaca na USGM, 15 casos foram confirmados pelo ECF, resultando em uma concordância diagnóstica de 21,62% (n = 8) entre os dois exames. A Comunicação Interventricular (CIV) foi a cardiopatia mais prevalente, representando 20% dos casos isolados. Dos 15 casos com alteração cardíaca em ECF, dois foram transferidos para um hospital especializado e cinco evoluíram a óbito.

Conclusão: A alteração cardíaca fetal foi confirmada em menos da metade das gestantes encaminhadas após USGM, com concordância entre os exames em apenas oito casos. A capacitação contínua em USGM reduz custos e transtornos. Profissionais qualificados em ECF são essenciais para o diagnóstico precoce de CC, melhorando a assistência e diminuindo a mortalidade infantil.
НЕЙТРАЛИЗАЦИЯ ЗНАЧЕНИЙ ВРЕМЕННЫХ
ФОРМ В СОВРЕМЕННОМ НЕМЕЦКОМ ЯЗЫКЕ
Authors: Абдукадырова А.А.
Published: December 2024

Данная статья рассматривает актуальные проблемы реализации формы парадигматического потенциала временных форм в синтагматике немецкого языка. Основополагающую роль в исследовании выполняют отдельные временные формы, которые в немецкой грамматике образуют шестичленную оппозицию.
Важность данной статьи обусловлена тем, что в исследовании следует делать акцент на сближение значений плюсквамперфекта и претерит, которое может идти и со стороны плюсквамперфекта, в случае утраты этой формой признака «перфектность», и со стороны претерита.
Сопоставляя два пути нейтрализации в претеритальном ряду, можно сделать вывод, что контекст способствует приобретению форм новых значений, но контекст не в состоянии полностью исключить признак, входящий в набор, дифференциальных семантических признаков, составляющих парадигматический потенциал данной временной формы.
РОЛЬ ИНТОНАЦИИ В РЕАЛИЗАЦИИ
БРИТАНСКОГО ЮМОРА
Authors: Газимаева Х.А.
Published: December 2024

Юмор – явление многогранное и сложное. Данный феномен присутствует во всех культурах и пронизывает все сферы деятельности человека. В юморе находят отражение национальные черты характера и мировоззрение разных народов. В современном мире особое место занимает английский юмор. Этот тип юмора, который нередко называют «тонким», наиболее сложен для понимания представителей других культур, в связи с чем представляет особый интерес для изучения. Английские шутки содержат в себе культурный код британского народа, поэтому их изучение позволяет составить представление о специфике целой нации. В данной статье исследуется роль интонации в реализации звучащей английской шутки и в создании комического эффекта.
ЗНАЧЕНИЕ ИНОСТРАННОГО ЯЗЫКА В КОНТЕКСТЕ БИЗНЕСА
Authors: Джукаева М.А. , Муслимова М.И. , Муслимова К.И.
Published: December 2024

В профессиональной сфере используется специальная форма общения, именуемая деловым дискурсом. Необходимо использовать язык привычный к потребностям делового диалога, который можно характеризовать формой, профессиональностью и точностью, так как в бизнес-коммуникации язык общения точно передает информацию, поддерживая имидж обеих профессиональных сторон. Профессионалы- экономисты и финансисты применяют термины в отраслевом направлении, к примеру, ликвидный коэффициент, доходность дивидендов или доход капитала. Данная терминология используется, чтобы лучше донести экономические концепции. Профессиональный язык ведет к эффективности и точным переговорам среди профессионалов одного направления, давая возможность обмениваться идеями точно и всесторонне. Профессиональность и форма бизнес-дискурса наглядно заметны при использовании формы языка в бизнес-документации в форме отчета, переписок официальных и предложений. Эта атмосфера формально задает хороший тон взаимодействию между профессионалами, передавая уважение друг к другу и серьезность намерений, которые важны при решении деловых вопросов. Важный момент при развитии хороших отношения в бизнесе в диалоге играют такие моменты как понимание.
ОСОБЕННОСТИ ФУНКЦИОНИРОВАНИЯ КОГНИТИВНЫХ МЕХАНИЗМОВ ЧЕЛОВЕЧЕСКОГО СОЗНАНИЯ В ЯЗЫКОВОЙ КАРТИНЕ МИРА
Authors: Абдукадырова Т.Т. , Асуева Л.М.
Published: December 2024

Данная статья рассматривает актуальные проблемы современной лингвистики полноценные научные исследования, которой не представляются возможными вне контекста человека. Важность данной статьи обусловлена тем, что в исследовании следует сделать акцент на соотнесении мышления и системы языка, что представляется важным в рамках современного научного знания, а также на языковой картине мира, так как именно такая картина мира представляет собой отражение существующей объективной реальности, которая присутствует в языковом сознании народа – носителя конкретного языка. Таким образом, концепты следует рассматривать как единицы ментального уровня человеческого сознания. Они характеризуются сложной структурой и тесной связью с лингвокультурными чертами конкретной нации. Исходя из вышесказанного мы можем сделать вывод о том, концептосфера представляет собой совокупность концептов, которая отличается своей национально-культурной спецификой.
МОЛЧАНИЕ КАК ОДНА ИЗ ВАЖНЕЙШИХ ФОРМ
МЕЖЛИЧНОСТНОЙ И МЕЖКУЛЬТУРНОЙ КОММУНИКАЦИИ
Authors: Джукаева М.А. , Муслимова М.И. , Муслимова К.И.
Published: December 2024

В понимании термина лидерства в наше время, слова часто занимают много места в коридорах власти и принятий решений, молчание недооценивается и является инструментом, недостаточно используемым. Тишина в своей глубокой сути несет силу и красноречивость, в значительной мере повышающие эффективность лидерства. Природа молчания многогранна, а ее потенциал возможно раскрыть в области лидерства. Молчание представляет собой средство анализа себя и происходящего вокруг, точнее размышление над всем. Лидеры же постоянно завалены требованиями и информацией, а в лабиринте бесконечного шума, внутри и внешне, они могут затеряться. В тишине человек чувствует себя как в убежище, в измерении, где можно оглянуться назад, сделав шаг и поразмыслить. Таким образом лидер может обработать информацию, обдумать решение, согласовывая действие с основной целью и своими ценностями. Интроспективное молчание не отсутствие шума, это гармоничное действие со своими мыслями, делая паузу для понимания общей картины. Вот об этом мы и поговорим, углубившись в интригующую область молчания.
ВЫРАЖЕНИЕ МОДАЛЬНОСТИ В ДИСКУРСЕ
Authors: Дзейтова Х.Б.
Published: December 2024

Модальность-явление довольно многоаспектное и поэтому в лингвистической литературе высказываются разнообразные мнения по поводу сущности данного феномена, очень часто противоречивые, поэтому модальность, несмотря на огромное количество исследований продолжает привлекать внимание исследователей, в чём нам видится актуальность данной работы.
ПОЛЬЗА ДИСТАНЦИОННОГО ОБУЧЕНИЯ
Authors: Зекиева П.М. , Джамулаева Дж.Х.
Published: December 2024

Сегодня интернет является неотъемлемой частью нашей повседневной жизни. Он проник во все сферы общества, включая образование. Интернет активно используется в учебе и повседневных делах не только школьниками, но и взрослыми. Одной из форм обучения, которая стала особенно актуальной в настоящее время, считается дистанционное обучение. На сегодняшний день больше 70% людей, особенно женщин учатся дистанционно. В связи с этим в данной статье будут рассмотрены преимущества и недостатки данного обучения.
ПЕРЕВОД СТИЛИСТИЧЕСКИХ ПРИЕМОВ В ПРОИЗВЕДЕНИЯХ
«ПАДШИЕ» И «БЕГУЩИЙ В ЛАБИРИНТЕ»
Authors: Манцаева А.Н. , Дадаева М.М.
Published: December 2024

В данном исследовании проводится анализ стилистических приемов в произведениях «Падщие» и «Бегущий в лабиринте». Актуальность темы данной работы обусловлена тем, что не существует однозначного мнения о степени переводимости текстов, а особенно, художественных, важной частью которых является стилистика. На примере данного анализа можно проследить, возможно ли сохранить стиль при переводе. Объектом данной работы являет художественный текст. Предмет – степень переводимости стилистических особенностей текста на другой язык. Цель работы – выявить, какие стилистические проблемы возникают при переводе.
СПЕЦИФИКА ПОСТРОЕНИЯ АУДИОДЕСКРИПЦИИ
ДЛЯ МУЗЕЙНЫХ ЭКСПОНАТОВ
Authors: Раздуев А.В.
Published: December 2024

Статья посвящена анализу специфики построения аудиодескрипции для музейных экспонатов как лаконичного описания предметов и окружающего их пространства, которые непонятны лицам с ограниченными возможностями здоровья – плохо видящим и полностью незрячим людям без специальных словесных пояснений. Аудиодескрипция музейных экспонатов может быть представлена в виде аудиогидов или в ходе экскурсий в музеях. В рамках работы выявлены основные характеристики и определены ключевые проблемы построения описания для лиц, имеющих проблемы со зрением.
ВЛИЯНИЕ НЕКОРНЕВОЙ ПОДКОРМКИ ДЕРЕВЬЕВ ЯБЛОНИ
НА СОДЕРЖАНИЕ КАЛЬЦИЯ В ЛИСТЬЯХ
Authors: Горлова Т.С. , Айсанов Т.С.
Published: December 2024

В статье рассматривается вопрос влияния некорневой подкормки на содержание кальция в листьях яблони. Исследование актуально в связи с возрастающей проблемой дефицита кальция у молодых деревьев, что приводит к снижению урожайности и качества плодов в дальнейших этапах развития растений. Химический состав листьев имеет большое практическое значение в определении состояния растений, а также оказывает определяющее влияние на прохождение процессов метаболизма и формировании урожайности и качества плодов. На основании полученных данных в ходе проведения исследований было установлено, что применение кальцийсодержащих удобрений способствует повышению концентрации данного элемента в листьях изучавшихся сортов яблони. Объектом исследований являлись 7 сортов яблони среднего и позднего срока созревания, возделываемые в производственных условиях сада интенсивного типа в учебно-опытном хозяйстве Ставропольского ГАУ.
ОПТИМАЛЬНЫЕ ПОКАЗАТЕЛИ МИКРОКЛИМАТА В ПТИЦЕВОДЧЕСКОМ ПОМЕЩЕНИИ ДЛЯ КУР– НЕСУШЕК ХАЙСЕКС БРАУН
Authors: Бетигова М.Л.-А. , Тарамова Л.В.
Published: December 2024

Результаты данного исследования подчеркивают важность комплексного подхода к управлению микроклиматом в птичниках. Установленные параметры температуры и влажности важны для обеспечения оптимальных условий содержания кур-несушек, что напрямую влияет на их производительность. Независимо от сезона, соблюдение этих стандартов минимизирует риски, связанные со здоровьем птицы и в конечном итоге повышает экономическую эффективность фермы. Также была выявлена необходимость регулярного мониторинга качества воздуха для обеспечения соответствия стандартам. Специализированное оборудование и методы управления качеством воздуха становятся важнейшими инструментами в управлении процессами птицеводства, чтобы избежать значительных потерь, связанных с ухудшением здоровья птицы. С учетом этих данных необходимо разработать рекомендации по внедрению эффективных систем вентиляции и освещения, адаптированных к конкретным условиям птицефабрики. Это позволит не только поддерживать здоровую среду в помещениях, но и оптимизировать затраты на птицеводство и обеспечить устойчивое развитие отрасли.
СОРТА ПЕРЦА СЛАДКОГО СЕЛЕКЦИИ ЧЕЧЕНСКОГО
НИИСХ ДЛЯ ОТКРЫТОГО ГРУНТА
Authors: Терекбаев А.А. , Магомадов М.А.
Published: December 2024

В статье приводятся сведения о двух новых сортах перца сладкого, созданных Чеченским НИИСХ, которые отличаются ценными признаками и высокими показателями урожайности и качества, обладают хорошей транспортабельностью и лежкостью. Новые сорта обладают высокими вкусовыми, биохимическими и технологическими качествами плодов, устойчивы к болезням, вредителям, адаптированы для разных климатических зон выращивания. Эти сорта являются вкладом в решение задачи обеспечения продовольственной безопасности страны.
Quem pode fazer história pública? Um estudo de caso sobre a Brasil Paralelo
Authors: Maximo da Silva Joana , Aparecido Priori Angelo
Published: December 2024

A Brasil Paralelo, é uma produtora gaúcha de documentários, reportagens, filmes, programas, cursos e séries que abordam temas relacionados à política, história, filosofia, economia, educação, artes e atualidades. Na comemoração do bicentenário de Independência do Brasil, a produtora realizou ação em uma escola de nível fundamental em São Paulo para “levar ao conhecimento dos alunos alguns heróis da história brasileira”, dando vida a personagens ilustres da história do Brasil, tais como: D. Pedro I, Imperatriz Leopoldina, José Bonifácio, D. Pedro II e Princesa Isabel. Assim, este trabalho objetiva apresentar a ação da produtora, apontando os usos do passado, para defesa de interesses de grupos conservadores da sociedade, desqualificando o conhecimento produzido com rigor metodológico, o dominando de “doutrinário”, para legitimar suas produções. Analisar os conteúdos e ações da BP, são imprescindíveis para a produção de um referencial crítico para desmontar/desconstruir ideias não-científicas sobre a História.
O sindicalismo em educação em Minas Gerais:
Authors: Hideo Diniz Hiro Cássio
Published: December 2024

Este artigo se apresenta como um ensaio reflexivo sobre a história recente do sindicalismo em educação em Minas Gerais, partindo de suas ações desde a educação básica e alcançando o ensino superior, sobretudo na busca pela sua compreensão como um elemento de identidade coletiva da categoria docente da Universidade do Estado de Minas Gerais (UEMG). Presente na história brasileira desde o advento da República, o sindicalismo se constitui como um dos mais expressivos e importantes movimentos sociais que já existiu, tornando-se parte indispensável na compreensão da sociedade capitalista não apenas no Brasil, mas em todo o mundo. Na realidade nacional, está presente nos mais diferentes períodos dos últimos 120 anos, fazendo parte de estudos e reflexões de pesquisadores, estudantes e demais interessados em entender a vida social de nosso tempo. Não obstante, a educação brasileira não ficou a margem desse processo, e os trabalhadores que compõem o seu dia a dia, como professores e funcionários, também se organizaram coletivamente em seus próprios movimentos sindicais, fazendo de si como uma das categorias mais mobilizadas, organizadas e combativas da atualidade. Minas Gerais se tornou o berço de um sindicalismo em educação de destaque, e a UEMG é parte dessa recente história.
INFLUENCE OF HYDROTHERMAL REGIME ON SPRING WHEAT YIELD IN THE CONDITIONS OF THE REPUBLIC OF TUVA
Authors: Dongak Mir Slava
Published: December 2024

The objective of the study is to investigate the influence of climatic conditions on the yield of spring wheat varieties in the Republic of Tuva. The paper presents the results of three-year studies of soft spring wheat varieties Altayskaya 75 and Novosibirskaya 31 in the forest-steppe zone of the Republic of Tuva. The influence of temperature and precipitation on yield formation and 1000-grain weight was determined. A positive relationship was established between yield and precipitation during the period of active plant growth (tube emergence – heading) (r = 0.48). The amount of precipitation in June showed a positive closeness of the average relationship with yield and 1000-grain weight. Precipitation in August had a negative effect on yield formation and 1000-grain weight, showing a close inverse relationship (r = –0.74 and r = –0.71). June temperature positively correlates with yield and 1000-grain weight (r = 0.39, r = 0.44). The temperature of July is highly correlated with the yield (r = 0.79), but shows an inverse relationship with the 1000-grain weight (r = –0.74). The temperature of August has a weak positive relationship with the yield and the 1000-grain weight. In general, the hydrothermal regime of June has a high relationship with the yield, a medium-strength relationship with the 1000-grain weight. The July hydrothermal regime is positively associated with the yield and medium-strength with the 1000-grain weight. The revealed instability of the yield of spring wheat Altai 75 over time is attributed by us to the manifestation of the genotype, i.e. to the biological characteristics of the variety.
BIOCHEMICAL BLOOD PARAMETERS OF PREGNANT COWS INFECTED WITH BLV
Authors: Ostyakova Marina , Scherbinina Svetlana
Published: December 2024

The aim of the study is to investigate metabolic disorders in pregnant cows infected with bovine leukosis virus (BLV) and to determine their relationship with lymphocytic leukocytosis. The object of the study was the blood of BLV-infected cows (n = 8) and leukemia-free (n = 5) pregnant cows (2–9 years old, gestation period 2–7 months) of dairy productivity from a livestock farm in the Amur Region. In BLV-infected cows, the number of leukocytes ((17.2 ± 2.66) ∙ 109/l) and lymphocytes ((10.5 ± 2.88) ∙ 109/l) exceeded normal physiological parameters. Protein metabolism was characterized by low albumin levels ((26.8 ± 2.57) %) and high beta-globulin levels ((31.2 ± 1.12) %). Hypoalbuminemia and a sharp selective increase in beta-globulin levels are characteristic of beta-globulin plasmacytomas. There was a positive relationship between the lymphocyte count and beta-globulin levels (r = 0.1, p < 0.001). Mineral metabolism was characterized by low calcium levels ((2.1 ± 0.10) mmol/l), magnesium ((0.6 ± 0.05) mmol/l) and high phosphorus levels ((3.1 ± 0.21) mmol/l). Phosphorus concentration was associated with the number of leukocytes (r = 0.2, p < 0.001), lymphocytes (r = 0.3, p < 0.05). Calcium concentration was associated with the number of leukocytes (r = –0.1, p < 0.001) and lymphocytes (r = –0.1, p < 0.05). Carbohydrate metabolism was characterized by hypoglycemia ((0.4 ± 0.04) mmol/l) and a relationship with the number of leukocytes (r = –0.4, p < 0.001) and lymphocytes (r = –0.1, p < 0.01), which confirmed the increased use of glucose by the leukemic process. The level of alanine aminotransferases (ALT) exceeded the norm and was (39.7 ± 7.02) U/l. There were positive relationships between lymphocytic leukocytosis and the level of aspartate aminotransferases (AST): AST – r = 0.2, p < 0.001; ALT – r = 0.8, p < 0.001. In pregnant cows free from BLV, the number of leukocytes ((11.4 ± 1.00) ∙ 109/l) and lymphocytes ((5.2 ± 0.80) ∙ 109/l) was within the normal range, but the level of phosphorus was increased ((2.9 ± 0.27) mmol/l) and the level of calcium was decreased ((2.2 ± 0.12) mmol/l). Increased levels of alanine aminotransferases, bilirubin, phosphorus, dysproteinemia, hypoalbuminemia, hypoglycemia, hypocalcemia characterized the metabolism of BLV-infected pregnant cows and indicated damage to hepatocytes and dystrophic liver damage.
ASSESSMENT OF USING TISSUE PREPARATIONS EFFICIENCY IN DAIRY CATTLE BREEDING
Authors: Pushkarev Ivan , Kureninova Tat'yana , Belyayeva Nina
Published: December 2024

The aim of the study is to compare the effectiveness of the use of tissue preparations on milk producti-vity and biochemical blood parameters of cows. The experiment was conducted in 2023 on Simmental cows during the milking period in the conditions of the branch of the Federal State Budgetary Scientific Institution of the Federal Research Center of Cattle Breeding Experimental Station Novotalitskoye of the Charyshsky District of the Altai Region. The experimental cows were administered tissue biostimulants: Experimental Group 1 – biostimulgin at a dose of 30 ml/head, Group 2 – ASD-2 fraction at a dose of 2 ml/head in combination with Eleovit at a dose of 10 ml/head, Group 3 – a tissue preparation at a dosage of 22.5 ml per head per day. The tissue preparations under study were administered subcutaneously in the lower third of the neck 4 times with an interval of 14 days. The experiment showed that the tissue biostimulant had the greatest impact on the milk productivity of the experimental cows. During the first 60 days of lactation, milk yield in animals of experimental group III increased by 4.2 % compared to the control. Milk fat from animals of experimental group III was 4.9 % (p ˂ 0.05) higher than from cows of the control group. According to blood parameters, it was revealed that the amount of total protein increased by 7.4 % (p ˂ 0.05), albumins by 2.0 % (p ˂ 0.01) and AST by 21.5 % (p ˂ 0.01) compared to the control va-lues. The use of tissue preparations in experimental groups I and II was less effective and contributed to an increase in the total protein by 1.6 and 7.8 % (p ˂ 0.05), AST by 2.0 (p ˂ 0.05) and 9.5 % compared to the parameters of the control animals. Animals of the third experimental group generated additional profit of 2,787 rubles.
VETERINARY AND SANITARY EXAMINATION OF YAK MILK AND PHYSICAL AND CHEMICAL COMPOSITION OF NATIONAL DAIRY PRODUCTS OF THE REPUBLIC OF TUVA
Authors: Saryglar Lyudmila , Makarov Andrey , Khanipova Vera
Published: December 2024

The aim of research is to conduct a veterinary and sanitary examination of yak milk, determine the mig-ration of some macro- and microelements from yak milk to national dairy products and give their sanitary assessment. The studies were carried out in 2023 at the Research and Testing Center of the Krasnoyarsk State Agrarian University. Samples of yak milk and national processed products, such as khoytpak and kurut, were subjected to physicochemical studies, 10 samples of each type. Organoleptic (color, consistency, taste, smell) and physicochemical parameters of yak milk and national processed dairy products (khoytpak and kurut) were obtained – density, acidity, moisture content, protein, fat, and the quantitative and qualitative composition of the products was analyzed for the content of some macro- and microelements, such as magnesium, potassium, sodium, zinc, calcium, iron, copper, phosphorus. Based on the results of organoleptic and physicochemical studies, it was established that kurut had the highest nutritio¬nal value among the presented samples. Kurut was superior to yak milk and khoytpak in fat, protein, micro- and macroelement composition, while kurut was superior to yak milk and khoytpak in the content of most micro- and macroelements by 7 or more times. All samples that were subjected to examination met the quality requirements for milk and dairy products, were complete in nutritional terms in terms of physicochemical composition and can be used as complete food products among the population of ethnic peoples of the Siberian and Far Eastern Federal Districts.