bluuebunny/crossref_metadata_2025 huggingface dataset:
Geriatric Oncology: A 5-Year Strategic Plan
Authors: Diaz Fernando C. , Hamparsumian Anahid , Loh Kah Poh , Verduzco-Aguirre Haydeé , Abdallah Maya , Williams Grant R. , Hsu Tina , Soto-Perez-de-Celis Enrique , Elias Rawad
Published: May 2024

The increasing rate of the older adult population across the world over the next 20 years along with significant developments in the treatment of oncology will require a more granular understanding of the older adult population with cancer. The ASCO Geriatric Oncology Community of Practice (COP) herein provides an outline for the field along three fundamental pillars: education, research, and implementation, inspired by ASCO's 5-Year Strategic Plan. Fundamental to improving the understanding of geriatric oncology is research that intentionally includes older adults with clinically meaningful data supported by grants across all career stages. The increased knowledge base that is developed should be conveyed among health care providers through core competencies for trainees and continuing education for practicing oncologists. ASCO's infrastructure can serve as a resource for fellowship programs interested in acquiring geriatric oncology content and provide recommendations on developing training pathways for fellows interested in pursuing formalized training in geriatrics. Incorporating geriatric oncology into everyday practice is challenging as each clinical setting has unique operational workflows with barriers that limit implementation of valuable geriatric tools such as Geriatric Assessment. Partnerships among experts in quality improvement from the ASCO Geriatric Oncology COP, the Cancer and Aging Research Group, and ASCO's Quality Training Program can provide one such venue for implementation of geriatric oncology through a structured support mechanism. The field of geriatric oncology must continue to find innovative strategies using existing resources and partnerships to address the pressing needs of the older adult population with cancer to improve patient outcomes.
Paraneoplastic Vitiligo Associated With Adrenocortical Carcinoma
Authors: Goodkin David Alan , Failor Richard Alan , Habra Mouhammed Amir
Published: May 2024

Malignancies may induce clinical sequelae distant from the sites of the tumor. Such paraneoplastic phenomena are known to affect many organs, including the skin. Vitiligo is a disorder of patchy depigmentation, appearing as white macules with distinct margins. Rarely, vitiligo has been reported as a paraneoplastic occurrence, in the settings of pituitary adenoma, thymoma, gastric carcinoma, and lymphoma. We now describe a man presenting with the abrupt onset of vitiligo on the hands coinciding with recurrence of adrenocortical carcinoma (ACC) in the abdomen. The vitiligo rapidly dissipated following resection of his cancer. We believe this to be the first report of paraneoplastic vitiligo associated with ACC. Endocrinologists typically manage ACC and should be aware of this link, as the de novo observation of vitiligo may signal the onset or recurrence of underlying tumor. Other practitioners that encounter patients with new vitiligo should add ACC to their differential diagnosis of potential underlying conditions.
Hypercalcemia Secondary to Elevated PTHrP in an Infant Followed by Progression to Nephrotic Syndrome
Authors: Gimeno Alex F , Hunley Tracy E , Kelley Jennifer C
Published: May 2024

In infants, hypercalcemia from elevated parathyroid hormone-related protein (PTHrP) is rare, often signaling neoplasm or renal or urinary anomalies. We report an infant who presented with failure to thrive and hypercalcemia at 10 months old, with initial evaluation showing elevated PTHrP of unclear etiology with imaging negative for neoplasm and no structural anomalies of the kidneys or ureters on ultrasound. Within 6 months of presentation, the patient developed nephrotic syndrome and by 2 years had progressed to end-stage kidney disease, necessitating kidney transplantation. Genetic testing was inconclusive but suggested congenital nephrotic syndrome. While reports of hypercalcemia secondary to elevated PTHrP exist in children with known structural renal anomalies, this is the first to demonstrate hypercalcemia and PTHrP elevation before detection of renal abnormalities. Experimental models have suggested a role for increased PTHrP expression in renal cells following acute kidney injury from nephrotic syndrome, and clinically detectable PTHrP levels may indicate progression of renal injury. We suggest monitoring of renal function for early detection of nephrotic syndrome in infants and children with elevated PTHrP who otherwise lack anatomical renal anomalies or detectable malignancies.
Gender-Diverse Youth with Turner Syndrome: Special Management Considerations
Authors: Eitel Kelsey B , Zenno Anna , Di Blasi Carolina , Fechner Patricia Y , Hodax Juanita K
Published: May 2024

Turner syndrome (TS) is a sex chromosome abnormality characterized by short stature and primary hypogonadism with increased risk for cardiovascular disease, osteopenia, metabolic syndrome, diabetes mellitus, abnormal liver enzymes, and impairment of nonverbal learning skills. Gender-diverse youth include youth who have a gender identity that is different from their sex assigned at birth. They have an increased risk of suicidality, which is decreased in those who receive gender-affirming care. There have been no prior reports on the association or management of gender-diverse youth with TS. We describe 3 cases of gender-diverse youth with TS that highlight the importance of discussing gender identity in patients with hypogonadism in need of sex hormone replacement. Goals of care should be discussed to determine whether estrogen or testosterone replacement aligns best with gender identity. If a patient chooses to start testosterone, special considerations of risks such as erythrocytosis, osteopenia, and cardiovascular disease should be discussed in relation to their TS.
Two Cases of Sitosterolemia Falsely Diagnosed as Familial Hypercholesterolemia: Could Digging Deeper Have Avoided Harm?
Authors: Guay Simon-Pierre , Paquette Martine , Blais Chantal , Gosse Géraldine , Baass Alexis
Published: May 2024

Sitosterolemia is a rare monogenic lipid disease characterized by the excessive uptake of phytosterols and their accumulation in blood and tissues. Clinically, it can present with hypercholesterolemia and xanthomas, often causing it to be misdiagnosed as familial hypercholesterolemia (FH). The diagnosis of sitosterolemia can easily be confirmed and distinguished from FH with a sterol profile and genetic investigations. Here, we report a sibship of 2 sisters with sitosterolemia initially misdiagnosed as FH. This case report illustrates the importance of considering rare conditions, such as sitosterolemia, as a differential diagnosis in patients with hypercholesterolemia, xanthomas, and hematologic anomalies. It also emphasizes the underdiagnosis of sitosterolemia and the benefits of using sterol profiles and genetic testing in the diagnostic process to initiate the appropriate therapy and avoid harm to patients.
Government Data of the People, by the People, for the People: Navigating Citizen Privacy Concerns
Authors: Bowen Claire McKay
Published: May 2024

The data privacy community generally agrees that government data should be more widely accessible, especially being of the people (data collected about them), by the people (collected and supported using taxpayer dollars), and for the people (providing public and social good). But what to protect in that data and how to do so are highly and intensely debated. This paper discusses the fundamental tradeoff between data privacy and data usefulness—and how determining an appropriate balance can be difficult. The paper also provides thoughts on what must be addressed to help shape the future of data privacy, make meaningful contributions to its policy debates, and ensure the responsible representation of people in data.
When Privacy Protection Goes Wrong: How and Why the 2020 Census Confidentiality Program Failed
Authors: Ruggles Steven
Published: May 2024

The U.S. Census Bureau implemented a new disclosure control strategy for the 2020 Census that adds deliberate error to every population statistic for every geographic unit smaller than a state, including metropolitan areas, cities, and counties. This article traces the evolving rationale for the new procedures and assesses the impact of the 2020 disclosure control on data quality. The Census Bureau argues that the traditional disclosure controls used for the 2010 and earlier censuses revealed the confidential responses of millions of Americans. I argue that this claim is unsupported, and that there is no evidence that anyone's responses were compromised. The new disclosure control strategies introduce unnecessary error with no clear benefit; in fact, the new procedures may actually be less effective for protecting confidentiality than the procedures they replaced. I conclude with recommendations for minimizing disclosure risk while maximizing data utility in future censuses.
Gabriel Zucman: Winner of the 2023 Clark Medal
Authors: Saez Emmanuel
Published: May 2024

The 2023 John Bates Clark Medal of the American Economic Association was awarded to Gabriel Zucman, associate professor of economics at the University of California, Berkeley for his fundamental contributions to the study of inequality and taxation. Through meticulous empirical work and creative methodological approaches, he has revealed key trends about the concentration of global wealth, the size and distribution of tax evasion, and the tax-saving strategies of multinational companies. These findings have had a profound impact on the academic literature and on global policy debates. He has shifted the way economic research is done by showing that measurement can have a large impact in our field and on the world, inspiring many younger scholars to follow in his footsteps.
The Shifting Reasons for Beveridge Curve Shifts
Authors: Barlevy Gadi , Faberman R. Jason , Hobijn Bart , Şahin Ayşegül
Published: May 2024

We discuss how the relative importance of factors that contribute to movements of the US Beveridge curve has changed from 1959 to 2023. We review these factors in the context of a simple flow analogy used to capture the main insights of search and matching theories of the labor market. Changes in inflow rates, related to demographics, accounted for Beveridge curve shifts between 1959 and 2000. A reduction in matching efficiency, that depressed unemployment outflows, shifted the curve outwards in the wake of the Great Recession. In contrast, the most recent shifts in the Beveridge curve appear driven by changes in the eagerness of workers to switch jobs. Finally, we argue that, while the Beveridge curve is a useful tool for relating unemployment and job openings to inflation, the link between these labor market indicators and inflation depends on whether and why the Beveridge curve shifted. Therefore, a careful examination of the factors underlying movements in the Beveridge curve is essential for drawing policy conclusions from the joint behavior of unemployment and job openings.
Abordagem cirúrgica de fratura blow-out através de acesso transconjuntival
Authors: Lima Gomes Nilvia Maria , Araújo Pacheco Brito Thainá , Jorge Garcia Juliana , Costa Moreira Lucya Giselle , Coelho Venas Nívea , Freitas de Assis Adriano
Published: May 2024

Introdução: a região orbitária é bastante suscetível a fraturas, devido a sua posição exposta e a ossos frágeis. As fraturas do tipo blow-out caracterizam-se pela fratura do assoalho orbitário com ou sem herniação de conteúdo para o seio maxilar, gerando consequências funcionais e estéticas. Relato do caso: paciente do sexo feminino, 48 anos de idade, vítima de queda da própria altura, compareceu ao Hospital Geral do Estado da Bahia com queixa de diplopia, apresentando fratura de assoalho de órbita direita. Foi programada uma abordagem transconjuntival e instalação de tela de titânio para reconstrução. Na alta hospitalar, a paciente negou diplopia, não apresentando prejuízos funcionais ou estéticos. Conclusão: o acesso transconjuntival possibilita uma adequada exposição do assoalho de órbita, para colocação de telas, deixando uma cicatriz imperceptível na conjuntiva. Apesar das vantagens, este acesso cirúrgico apresenta maior complexidade técnica, sendo pouco realizado pelos cirurgiões.
Prospective observational study on clinical profile of congenital anomalies of kidney and urinary tract (CAKUT) in children in central India: A study protocol
Authors: Kommareddy Anirudh , Vagha Jayant
Published: May 2024

Background Congenital anomalies of the kidney and urinary tract (CAKUT) are a group of structural abnormalities affecting these vital organs, frequently leading to chronic kidney disease in children. This study aims to comprehensively understand the clinical profile of CAKUT in children in Central India, an area with unique socio-demographic characteristics and limited prior research on this topic. Methods A prospective observational study will be conducted over three years in the pediatric department of AVBRH, a tertiary healthcare center in Central India. Data were collected through interviews with parents or guardians of children up to 18 admitted to the hospital. Clinical symptoms, prenatal history, physical examinations, and diagnostic investigations were meticulously documented. Expected outcome The study is expected to reveal the prevalence and clinical profile of CAKUT in Central Indian children. Anticipated outcomes include insights into anomalies, clinical symptoms, and potential correlations with factors like prenatal care and consanguineous marriages. Diagnostic investigations will help assess the severity of renal impairment. The results may also uncover regional variations and have implications for public health initiatives aimed at early intervention and improved patient care. However, these are preliminary expectations that are subject to confirmation through the completion of the study.
The top 50 most-cited articles about COVID-19 and the complications of COVID-19: A bibliometric analysis
Authors: Singh Tanya , Rao Padubidri Jagadish , Shetty Pavanchand H. , Antony Manoj Matthew , Mary Therese , Thejaswi Pallempati Bhanu
Published: May 2024

Background

This bibliometric analysis examines the top 50 most-cited articles on COVID-19 complications, offering insights into the multifaceted impact of the virus. Since its emergence in Wuhan in December 2019, COVID-19 has evolved into a global health crisis, with over 770 million confirmed cases and 6.9 million deaths as of September 2023. Initially recognized as a respiratory illness causing pneumonia and ARDS, its diverse complications extend to cardiovascular, gastrointestinal, renal, hematological, neurological, endocrinological, ophthalmological, hepatobiliary, and dermatological systems.

Methods

Identifying the top 50 articles from a pool of 5940 in Scopus, the analysis spans November 2019 to July 2021, employing terms related to COVID-19 and complications. Rigorous review criteria excluded non-relevant studies, basic science research, and animal models. The authors independently reviewed articles, considering factors like title, citations, publication year, journal, impact factor, authors, study details, and patient demographics.

Results

The focus is primarily on 2020 publications (96%), with all articles being open access. Leading journals include The Lancet, NEJM, and JAMA, with prominent contributions from Internal Medicine (46.9%) and Pulmonary Medicine (14.5%). China played a major role (34.9%), followed by France and Belgium. Clinical features were the primary study topic (68%), often utilizing retrospective designs (24%). Among 22,477 patients analyzed, 54.8% were male, with the most common age group being 26-65 years (63.2%). Complications of COVID-19 affected 13.9% of patients, with a recovery rate of 57.8%.

Conclusion

Analyzing these top-cited articles offers clinicians and researchers a comprehensive, timely understanding of influential COVID-19 literature. This approach uncovers attributes contributing to high citations and provides authors with valuable insights for crafting impactful research. As a strategic tool, this analysis facilitates staying updated and making meaningful contributions to the dynamic field of COVID-19 research.
Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio predicting hospital length of stay and mortality in young COVID-19 patients: A retrospective study
Authors: El-Menyar Ayman , Khan Naushad A. , Asim Mohammad , Al-Thani Hassan , Abukhattab Mohammed , Al Maslamani Muna
Published: May 2024

Background This study investigated the utility of platelet-to-lymphocyte ratio (PLR) and Neutrophil-to-Lymphocyte ratio (NLR) in patients with COVID-19 with respect to age, early (a week) vs. delayed recovery (> a week) and mortality. Methods This was a retrospective study including 1,016 COVID-19 patients. The discriminatory power and multivariate logistic regression analysis were performed. Results The mean age of patients was 45 (± 13.9), and 75.7% were males. Older patients had elevated NLR, PLR, D-dimer, CRP, and Interleukin-6 levels and longer hospital stay than the younger group (p < 0.001). In-hospital mortality was higher in older adults (26.9% vs. 6.6%, p =0.001). On-admission NLR (5.8 vs. 3.2; P= 0.001) and PLR (253.9±221.1 vs. 192.2±158.5; p = 0.004) were higher in the non-survivors than survivors. Both PLR and NLR displayed significant discriminatory ability for mortality. NLR had a higher AUC and specificity, while PLR exhibited slightly higher sensitivity. In individuals aged ≤55, NLR showed superior discrimination (AUC=0.717) compared to PLR (AUC=0.620). Conversely, for older adults, PLR displayed enhanced discrimination (AUC=0.710), while NLR showed AUC=0.693. Conclusion Higher admission NLR and PLR levels were associated with delayed recovery, whereas an enhanced NLR was associated with considerably higher mortality in older COVID-19 patients.
Assess The Workload Management Model and Enhanced Quality Control in The Central Sterile Supply Department: A Study Protocol.
Authors: Supare Prachi Pralhad , Kanyal Deepika
Published: May 2024

Introduction The Central Sterile Supply Department (CSSD) plays a crucial role in ensuring the safety and efficacy of medical instruments and equipment used in healthcare settings. Effective workload management and quality control are essential for maintaining high standards of patient care and minimizing the risk of healthcare-associated infections. This study protocol aims to assess the implementation and impact of a new workload management model and enhanced quality control measures in a CSSD setting. Methods The study will employ a mixed-methods approach, including quantitative analysis of workload data, qualitative interviews with CSSD staff, and observational assessments of workflow and quality control procedures. The workload management model under investigation involves the allocation of resources based on demand patterns and the implementation of scheduling algorithms to optimize staff efficiency. Enhanced quality control measures include the implementation of advanced sterilization technologies, rigorous inspection protocols, and continuous staff training initiatives. Results The study expects to provide insights into the effectiveness of the workload management model in optimizing resource allocation and improving staff productivity. Additionally, it aims to evaluate the impact of enhanced quality control measures on the reliability and safety of instrument sterilization processes. Findings from this study will inform recommendations for further improvements in CSSD operations and contribute to the advancement of best practices in sterile supply management. Conclusion The successful implementation of an effective workload management model and enhanced quality control measures in the CSSD is crucial for maintaining patient safety and ensuring the efficient functioning of healthcare facilities. By systematically evaluating the implementation and impact of these interventions, this study protocol seeks to contribute to the ongoing improvement of CSSD operations and the enhancement of healthcare quality.
Typologia postaci proroka Elizeusza we wczesnej tradycji monastycznej
Authors: Paczkowski Mieczysław Celestyn
Published: May 2024

Artykuł omawia kwestię rozumienia i praktycznego znaczenia proroctwa w starożytnym monastycyzmie w odniesieniu do postaci Elizeusza. Charyzmat prorocki był silnie zakorzeniony z środowisku ascetycznym. Starożytna literatura monastyczna odnotowuje działanie Ducha Świętego w kontekście ascetycznym. Dar proroctwa pojawia się u słynnych ascetów i mistrzów duchowych jako szczególna cecha. Biblijne postacie Eliasza i Elizeusza są postrzegane przez starożytnych mnichów jako „typy” i wzorce poszukujących doskonałego i duchowego życia (tj. „życia na wzór proroków”). Biografia proroka Elizeusza była wykorzystywana typologicznie w literaturze egzegetycznej, hagiograficznej i ascetycznej. Artykuł przedstawia także obecność innych darów duchowych (moc cudotwórcza i charyzmat „rozeznania serc”).
Okazjonalność przymiotników temporalnych w języku polskim
Authors: Grochowski Maciej
Published: May 2024

OCCASIONAL USE OF TEMPORAL ADJECTIVES IN POLISH
Occasional expressions help in referring the predicate to an extralinguistic object, and they serve as a means of its identification. The author of the article presents semantic descriptions of the following Polish temporal adjectives which express the simultaneity of the action with the speech act, namely aktualny [up-to-date], obecny [present], bieżący [current], dzisiejszy [today’s], teraźniejszy [presentday]. These units can be used occasionally. In this case, they are characterized by several syntactic features. First, they occur only in attribitive positions, never in predicative ones. Second, they cannot be negated. Third, they do not occur with indefinite pronouns. Fourth, they cannot co-occur with metapredicative operators. Fifth, they are not gradable.
Kilka pytań o samotną matkę i samodzielną matkę i ich opis leksykograficzny
Authors: Dróżdż-Łuszczyk Katarzyna
Published: May 2024

A FEW QUESTIONS ABOUT SAMOTNA MATKA AND SAMODZIELNA MATKA, AND THEIR LEXICOGRAPHIC DESCRIPTION
The author raises questions about how the terms samotna matka [single mother] and samodzielna matka [independent mother] are accounted for in a lexicographic description, whether they are considered discontinuous units, and what relationships exist between them. The author of the article presents corpus data that allows dating the appearance of the term samotna matka and the collocation samodzielna matka in Polish. The author comments on selected definitions of the adjective samotny (lonely). Then, she presents arguments in favour of recognising the combination samotna matka as a linguistic unit. Similar arguments were presented for the collocation samodzielna matka. The article also addresses issues of differences in valuation associated with the discussed collocations and indicates how a new collocation affects the meaning of the older unit.
O poprawności językowej tekstów generowanych przez SI na przykładzie ChatuGPT
Authors: Mazur Rafał
Published: May 2024

LANGUAGE ACCURACY OF TEXTS GENERATED BY AI: A CASE STUDY OF CHATGPT
The article aims to assess the linguistic accuracy of texts generated by ChatGPT, based on queries that mirror the instructions found in the 2023 secondary school final exam in Polish language and literature. The analysis focused on identifying and classifying language errors and evaluating their frequency. The results of the analysis revealed a varied level of accuracy in AI-generated texts. Most errors occurred in texts containing more complex constructions, where correct formulation required a comprehensive understanding of grammatical rules. The conclusions drawn from the analysis offer insights into the limitations of AI, which users should be mindful of when editing texts using chatbots.
Anotacja socjolingwistyczna w Korpusie dawnych polskich tekstów dramatycznych (1772–1939)
Authors: Pastuch Magdalena , Mitrenga Barbara , Wąsińska Kinga
Published: May 2024

SOCIOLINGUISTIC ANNOTATION IN THE CORPUS OF OLD POLISH DRAMATIC TEXTS (1772–1939)
The article presents the criteria applied in the sociolinguistic annotation in the Corpus of old Polish dramatic texts (1772–1939) (KorTeDa). This level of annotation was about assigning the three basic sociolinguistic variables: age, sex and social status to all the utterances of drama characters (except for collective statements). Six values were selected for determining age (underage, young adult, middle- aged adult, older adult (senior), indeterminate adult, indeterminate); three for sex (female, male, indeterminate); and four for social status (low, medium, high, indeterminate). The article shows the interdependence between those factors and the historical, social and cultural context. Additionally, the authors illustrated substantial and technical problems they faced during the process of this type of annotation. KorTeDa may become an important tool for analysing the history of the Polish language taking into account the methods of corpus linguistics and sociopragmatics.
Specyfika staropolszczyzny a anotacja gramatyczna. O lematyzacji tekstu staropolskiego
Authors: Wismont Magdalena , Zalejarz Kinga , Nowak-Pasterska Ewa , Rojszczak-Robińska Dorota
Published: May 2024

SPECIFIC FEATURES OF OLD POLISH LANGUAGE AND GRAMMATICAL ANNOTATION: LEMMATIZATION OF OLD POLISH TEXTS
The article is dedicated to grammatical annotation of Old Polish texts. It discusses the problem with the lemmatization of a medieval text. In the Apocrypha tool, a lemma is not the same as the basic form of a word. It is only a dictionary form, or a kind of a label. The author of the article presents the reasons for this decision and the adopted rules for assigning lemmas to different grammatical classes. The article also shows the criteria of the repartition of lemmas. These criteria are the frequency of the basic form in the text or texts, the persistence of the form or the differentiation of meanings. Third person pronouns turned out to be particularly difficult for lemmatization. According to the accepted rules, they have a gender, but do not conjugate with a gender (which forced, for example, the adoption of the masculine lemma ONY). The other examples are forms such as siebie, sobie [self], for which the lemma JA was adopted. The article also describes the issues of determining the lemma boundary when annotating words conjugated with different single morphemes: particles, agglutinants or residual forms of personal pronouns. All of the solutions adopted in the tool and presented in the article aimed at respecting the Old Polish language specific features while facilitating the analysis of the material.
Debates contemporáneos sobre derecho de familia, género y sexualidad
Authors: Beltrán y Puga Alma
Published: May 2024

Este ensayo discutirá las aportaciones que los estudios de género y sexualidad han realizado para el entendimiento del derecho de familia como un campo normativo más igualitario entre hombres y mujeres, así como la deconstrucción de roles de género y sexualidad heterosexuales. El objetivo es sistematizar las críticas que se han realizado desde la academia norteamericana y latinoamericana a la construcción del derecho de familia como un campo del derecho privado. La crítica feminista promueve repensarlo como un área de intervención importante para señalar las desigualdades que todavía aquejan a las mujeres (y a las personas que no se conforman con roles binarios de la sexualidad) en sus relaciones familiares, afectivas y económicas.
Public perceptions of health and social care: notes on the British Social Attitudes survey
Authors: Clough Isobel
Published: May 2024

The editor explores the results of the latest British Social Attitudes survey and the implications of low public satisfaction for the NHS and its governance.
Organisational Dynamics of University Social Capital: Developing Constructs Through Factor Analysis
Authors: Toyon Mohammad Abu Sayed
Published: May 2024

This study is designed to illuminate the role of four key constructs—teacher-student relationships, peer networks, satisfaction with support services, and employability trust—in shaping the social capital within universities. Utilising a sample of 1902 working students derived from the Eurostudent VII survey data, this research applies both exploratory and confirmatory factor analysis to validate the proposed model. The findings indicate that all four constructs demonstrate statistically significant and positive associations with university social capital. Crucially, the measures of reliability and validity are within an acceptable range, lending credibility to the findings. The teacher-student relationship was found to be the most influential factor, highlighting its crucial value in the functioning of social capital inside universities. Along with providing a framework for future studies on the ever-changing nature of social capital in universities, the results highlight the significance of cultivating an interconnected academic community, which enriches the educational organisation as a whole.
Neural Technologies for Objects Classification with Mobile Applications
Authors: Sidenko Ievgen , Kondratenko Galyna , Heras Oleksandr , Kondratenko Yuriy
Published: May 2024

This paper is related to the study of the features of the neural technologies’ application, in particular, ResNet neural networks for the classification of objects in photographs. The work aims to increase the accuracy of recognition and classification of objects in photographs by using various models of the ResNet neural network. The paper analyzes the features of the application of the corresponding models in comparison with other architectures of deep neural networks and evaluates their efficiency and accuracy in the classification of objects in photographs. The process of data formation for training neural networks, their processing and sorting is described. A web application and a mobile application for recognizing and classifying objects in a photo were also developed. A system for classifying objects, in particular airplanes in photographs, was developed using neural network technologies. It gives a recognition and classification accuracy of about 95%. Research results of ResNet models are of great practical importance, as they can improve the classification accuracy of various images. Features of ResNet, such as the use of skip connections or residual connections, make it effective in the relevant tasks. The results of the study will help to implement ResNet in various fields, including medicine, automatic pattern recognition and other areas where the classification of objects in photographs is an important task.
All-fiber multifunction differential absorption CO2 lidar integrating single-photon and coherent detection
Authors: Qiang Wei , Wang Chong , Wang Yu , Jiang Yifan , Li Yudie , Xue Xianghui , Dou Xiankang
Published: May 2024

This study demonstrates a differential absorption lidar (DIAL) for CO2 that integrates both single-photon direct detection and coherent detection. Based on all-fiber 1572 nm wavelength devices, this compact lidar achieves detection of CO2 concentration, wind field, and single photon aerosol backscattering signal. First, by comparing DIAL with VAISALA-GMP343, the concentration deviation between the two devices is less than 5 ppm, proving the accuracy of the DIAL. Second, through the scanning detection experiment in Chaohu Lake, Hefei, not only the CO2 concentration between single-photon detection and coherent detection but also the wind field was obtained, proving the multifunctionality and stability of the DIAL. Benefiting from the advantages of combined the two detection methods, single photon detection offers 3-km CO2 and aerosol backscattering signals; coherent detection offers a 360-m shorter blind zone and wind field. This DIAL can achieve monitoring of CO2 flux and sudden emissions, which can effectively compensate for the shortages of in-situ sensors and spaceborne systems.
Fringe-based depth segmentation via minimum-fringe-period-based singular points extraction
Authors: Wu Jiahao , Zhang Shaohui , Huang Yifan , Hao Qun
Published: May 2024

In the field of machine vision, depth segmentation plays a crucial role in dividing targets into different regions based on abrupt changes in depth. Phase-shifting depth segmentation is a technique that extracts singular points to form segmentation lines by leveraging the phase-shifting invariance of singular points in different wrapped phase maps. This makes it immune to color, texture, and camera exposure. However, current phase-shifting depth segmentation techniques face challenges in the precision of segmentation. To overcome this issue, this paper proposes a singular points extraction technique by constructing a more comprehensive threshold with the help of the minimum period of the phase map. Taking full advantage of the proposed technique, mean-value points and order singular points are accurately filtered out, and the integrity of segmentation lines in high-curvature regions can be guaranteed. During optimization processing, the precision of segmentation is improved by employing a low-cost morphology-based optimization model. Simulation results demonstrate the segmentation accuracy reaches up to 98.58% even in a noisy condition. Experimental results on different objects indicate that the proposed method exhibits good generalization and robustness.
Broadband generation of a multi-polarization multi-beam using a receiving-transmitting metasurface
Authors: Guo Wen-Long , Yuan Fang , Xu He-Xiu
Published: May 2024

Generating multiple beams in distinct polarization states is promising in multi-mode wireless communication but still remains challenging in metasurface design. Here, we theoretically and experimentally demonstrate a concept of broadband receiving-transmitting metasurface and its application to the generation of multi-polarization multi-beam. By employing U-slot patch, an efficient receiving-transmitting element with full phase coverage is designed within a wide bandwidth. Based on this architecture, a methodology is proposed to generate dual spin-decoupled beams and then developed into the strategy of generating multiple beams at different linear polarizations. To verify our strategy, two lens antennas, respectively radiating dual-spin dual-beam and quad-polarization quad-beam, are devised. With multi-polarization multi-beam radiated, the two lens antennas are both with whole aperture efficiency above 40% within the bandwidth of 10.6–12.3 GHz (14.8%), firmly validating our strategy and design.
Multi-function digital THz-metasurfaces based on phase change materials
Authors: Naghshpour Navid , Pakizeh Tavakol
Published: May 2024

An effective and digitally tunable reflective multi-function metasurface in the THz band is proposed. The introduced planar structure consists of an array of a well-designed double-split SRR (DSSRR) utilizing phase-change materials (PCMs) in the gap regions, leading to the controllable function of the metasurface due to the tuning of the crystallization level of PCMs. According to Pancharatnam-Berry's principle, this effect creates different electromagnetic responses only by employing two types of unit cells (bit-0 and bit-1) based on the proper addressing of the PCMs in the structure. It is reported that by digitally changing the coding sequence of the metasurface, it is individually capable of performing different functions such as polarization rotation, beam steering, and RCS reduction. The computational results have been verified by appropriate analytical equivalent electric-circuit modeling and the theory of antenna-arrays. The studied planar-structure with its tunable and coding properties might be suggested for advanced applications in THz sensing, communications, and imaging systems.
Relationship between HIV viral suppression and multidrug resistant tuberculosis treatment outcomes
Authors: Geiger Keri , Patil Amita , Budhathoki Chakra , Dooley Kelly E. , Lowensen Kelly , Ndjeka Norbert , Ngozo Jacqueline , Farley Jason E.
Published: May 2024

The impact of HIV viral suppression on multidrug resistant tuberculosis (MDR-TB) treatment outcomes among people with HIV (PWH) has not been clearly established. Using secondary data from a cluster-randomized clinical trial among people with MDR-TB in South Africa, we examined the effects of HIV viral suppression at MDR-TB treatment initiation and throughout treatment on MDR-TB outcomes among PWH using multinomial regression. This analysis included 1479 PWH. Viral suppression (457, 30.9%), detectable viral load (524, 35.4%), or unknown viral load (498, 33.7%) at MDR-TB treatment initiation were almost evenly distributed. Having a detectable HIV viral load at MDR-TB treatment initiation significantly increased risk of death compared to those virally suppressed (relative risk ratio [RRR] 2.12, 95% CI 1.11–4.07). Among 673 (45.5%) PWH with a known viral load at MDR-TB outcome, 194 (28.8%) maintained suppression, 267 (39.7%) became suppressed, 94 (14.0%) became detectable, and 118 (17.5%) were never suppressed. Those who became detectable (RRR 11.50, 95% CI 1.98–66.65) or were never suppressed (RRR 9.28, 95% CI 1.53–56.61) were at significantly increased risk of death (RRR 6.37, 95% CI 1.58–25.70), treatment failure (RRR 4.54, 95% CI 1.35–15.24), and loss to follow-up (RRR 7.00, 95% CI 2.83–17.31; RRR 2.97, 95% CI 1.02–8.61) compared to those who maintained viral suppression. Lack of viral suppression at MDR-TB treatment initiation and failure to achieve or maintain viral suppression during MDR-TB treatment drives differences in MDR-TB outcomes. Early intervention to support access and adherence to antiretroviral therapy among PWH should be prioritized to improve MDR-TB treatment outcomes.
External validation of a multi-biomarker-based score for predicting risk of cardiovascular disease in patients with rheumatoid arthritis
Authors: Sasso Eric H. , Mabey Brent , Flake Darl D. , Hitraya Elena , Chin Cheryl L. , Ben-Shachar Rotem , Gutin Alexander , Lanchbury Jerry S. , Curtis Jeffrey R.
Published: May 2024

Background

A multi-biomarker disease activity (MBDA)-based cardiovascular disease (CVD) risk score was developed and internally validated in a Medicare cohort to predict 3-year risk for myocardial infarction (MI), stroke or CVD death in patients with rheumatoid arthritis (RA). It combines the MBDA score, leptin, MMP-3, TNF-R1, age and four clinical variables. We are now externally validating it in a younger RA cohort.

Methods

Claims data from a private aggregator were linked to MBDA test data to create a cohort of RA patients ≥18 years old. A univariable Cox proportional hazards regression model was fit using the MBDA-based CVD risk score as sole predictor of time-to-a-CVD event (hospitalized MI or stroke). Hazard ratio (HR) estimate was determined for all patients and for clinically relevant subgroups. A multivariable Cox model evaluated whether the MBDA-based CVD risk score adds predictive information to clinical data.

Results

49,028 RA patients (340 CVD events) were studied. Mean age was 52.3 years; 18.3% were male. HR for predicting 3-year risk of a CVD event by the MBDA-based CVD risk score in the full cohort was 3.99 (95% CI: 3.51–4.49, p = 5.0×10−95). HR were also significant for subgroups based on age, comorbidities, disease activity, and drug use. In a multivariable model, the MBDA-based CVD risk score added significant information to hypertension, diabetes, tobacco use, history of CVD, age, sex and CRP (HR = 2.27, p = 1.7×10−7).

Conclusion

The MBDA-based CVD risk score has been externally validated in an RA cohort that is younger than and independent of the Medicare cohort that was used for development and internal validation.
Genetic manipulation of rod-cone differences in mouse retina
Authors: Morshedian Ala , Jiang Zhichun , Radu Roxana A. , Fain Gordon L. , Sampath Alapakkam P.
Published: May 2024

Though rod and cone photoreceptors use similar phototransduction mechanisms, previous model calculations have indicated that the most important differences in their light responses are likely to be differences in amplification of the G-protein cascade, different decay rates of phosphodiesterase (PDE) and pigment phosphorylation, and different rates of turnover of cGMP in darkness. To test this hypothesis, we constructed TrUx;GapOx rods by crossing mice with decreased transduction gain from decreased transducin expression, with mice displaying an increased rate of PDE decay from increased expression of GTPase-activating proteins (GAPs). These two manipulations brought the sensitivity of TrUx;GapOx rods to within a factor of 2 of WT cone sensitivity, after correcting for outer-segment dimensions. These alterations did not, however, change photoreceptor adaptation: rods continued to show increment saturation though at a higher background intensity. These experiments confirm model calculations that rod responses can mimic some (though not all) of the features of cone responses after only a few changes in the properties of transduction proteins.
An EPR model for predicting the bearing capacity of single and double-strip foundations near earth slope crests
Authors: Ismael Khalil Sadiq , Sulaiman Rafi’ Mahmoud
Published: May 2024

It is imperative to understand how foundations behave on earthen slopes to accurately predict their allowable carrying capacity in geotechnical engineering. A comprehensive finite element (FE) simulation with PLAXIS 2D was conducted to assess the effects of various parameters on the bearing capacity (BC) of single- and double-strip foundations placed near the earth’s slope crest. The specified parameters include foundation width (B) and depth (Df/B); setback distance between the slope edge and foundation (b/B); soil internal friction (ϕ) and cohesion (c); slope inclination (β); and spacing between foundations (S/B). In addition, the numerically simulated database was used to develop simple mathematical expressions for predicting the capacities in both cases using evolutionary polynomial regression (EPR). The results revealed that the bearing capacity of single- and double-strip foundations increased with an increase in all studied parameters except slope inclination. For single-strip foundations, the outcomes demonstrated that slope inclination has no impact on BC when it is located 6B from the slope edge. However, under interference conditions, the critical center-to-center spacing between foundations is 3–4B, beyond which they behave as individual foundations. Additionally, EPR provides a robust method of predicting the BC of single- and double-strip foundations within slope crests based on the strong correlation of various statistical criteria between simulated and predicted results from training, validation, and testing. Finally, according to sensitivity analysis, in both single and double-strip foundations resting on an earthen slope crest, b/B, B, and ϕ are the most important input parameters that impact the output results.
Can energy saving and emission reduction policies promote green transformation of industrial enterprises——The Case of China
Authors: Li Chunyan , Wang Deqi , Hu Rui , Zhang Fei , Li Mingna
Published: May 2024

In the context of the continued advancement of the green economy transition, the proactive pursuit of carbon emissions reduction and the early attainment of carbon neutrality goals have emerged as essential components in promoting high-quality economic development. Not only does it contribute to the creation of a community of human destiny, but it is also vital to the realization of sustainable development for human civilization. A dynamic evolutionary game model, which encompasses the interactions among government, enterprises, and the public, was constructed to examine the inherent impact mechanisms of the behavior of three players on the development of a green economy under the context of energy saving and emission reduction subsidies. The results showed that the incentive and punishment mechanisms served as effective tools for harmonizing the interests of system members. Within the mechanisms, the public demonstrated a higher sensitivity to rewards, while enterprises exhibited greater responsiveness to fines. Consequently, the government could influence the behavior of enterprises by incentivizing the public to serve as a third-party inquiry and oversight body. Simultaneously, the government could encourage enterprises to expedite green technology innovation by employing a combination of incentive and punishment mechanisms.
Misclassification of causes of death among a small all-autopsied group of former nuclear workers: Death certificates vs. autopsy reports
Authors: McComish Stacey L. , Liu Xirui , Martinez Florencio T. , Zhou Joey Y. , Tolmachev Sergey Y.
Published: May 2024

The U.S. Transuranium and Uranium Registries performs autopsies on each of its deceased Registrants as a part of its mission to follow up occupationally-exposed individuals. This provides a unique opportunity to explore death certificate misclassification errors, and the factors that influence them, among this small population of former nuclear workers. Underlying causes of death from death certificates and autopsy reports were coded using the 10th revision of the International Classification of Diseases (ICD-10). These codes were then used to quantify misclassification rates among 268 individuals for whom both full autopsy reports and death certificates with legible underlying causes of death were available. When underlying causes of death were compared between death certificates and autopsy reports, death certificates correctly identified the underlying cause of death’s ICD-10 disease chapter in 74.6% of cases. The remaining 25.4% of misclassified cases resulted in over-classification rates that ranged from 1.2% for external causes of mortality to 12.2% for circulatory disease, and under-classification rates that ranged from 7.7% for external causes of mortality to 47.4% for respiratory disease. Neoplasms had generally lower misclassification rates with 4.3% over-classification and 13.3% under-classification. A logistic regression revealed that the odds of a match were 2.8 times higher when clinical history was mentioned on the autopsy report than when it was not. Similarly, the odds of a match were 3.4 times higher when death certificates were completed using autopsy findings than when autopsy findings were not used. This analysis excluded cases where it could not be determined if autopsy findings were used to complete death certificates. The findings of this study are useful to investigate the impact of death certificate misclassification errors on radiation risk estimates and, therefore, improve the reliability of epidemiological studies.
Comparing fatal crash risk factors by age and crash type by using machine learning techniques
Authors: Alshehri Abdulaziz H. , Alanazi Fayez , Yosri Ahmed. M. , Yasir Muhammad
Published: May 2024

This study aims to use machine learning methods to examine the causative factors of significant crashes, focusing on accident type and driver’s age. In this study, a wide-ranging data set from Jeddah city is employed to look into various factors, such as whether the driver was male or female, where the vehicle was situated, the prevailing weather conditions, and the efficiency of four machine learning algorithms, specifically XGBoost, Catboost, LightGBM and RandomForest. The results show that the XGBoost Model (accuracy of 95.4%), the CatBoost model (94% accuracy), and the LightGBM model (94.9% accuracy) were superior to the random forest model with 89.1% accuracy. It is worth noting that the LightGBM had the highest accuracy of all models. This shows various subtle changes in models, illustrating the need for more analyses while assessing vehicle accidents. Machine learning is also a transforming tool in traffic safety analysis while providing vital guidelines for developing accurate traffic safety regulations.