bluuebunny/crossref_metadata_2025 huggingface dataset:
La regola del genere dei nomi di professioni nei manuali di italiano l2/ls
Authors: Frabotta Simona
Published: February 2025

Il femminile delle professioni è al centro del dibattito sul sessismo linguistico in Italia, soprattutto per quanto riguarda i sostantivi che indicano ruoli professionali di prestigio, come avvocato, ministro o architetto, che spesso vengono declinati al maschile anche quando si riferiscono a una donna. Grazie ai contributi della linguistica femminista, tuttavia, è sempre più diffusa la consapevolezza che l’uso di forme del cosiddetto maschile “non marcato” per indicare referenti femminili è il frutto di una concezione della lingua di stampo androcentrico e sono ormai diverse le istituzioni che ne sconsigliano l’uso e si sono espresse a favore di un linguaggio non sessista.
Nella presente ricerca si è analizzato il trattamento della regola di formazione dei femminili di professioni all’interno delle sezioni grammaticali di quindici testi di italiano L2/LS pubblicati negli ultimi dieci anni con l’obiettivo di osservare se le recenti indicazioni e raccomandazioni abbiano avuto un impatto e siano state assunte come modello linguistico.
Dai risultati emerge che non esiste un’esposizione omogenea della regola in questione e che, sebbene in alcuni casi essa venga illustrata in maniera approfondita, quando si cerca di rendere visibili le donne che svolgono professioni prestigiose, alcuni dei manuali analizzati consigliano l’uso del maschile “non marcato” o forniscono indicazioni approssimative riguardo l’attuale stato della questione.
Analisis Kapasitas Gudang menggunakan Metode Dedicated Storage dan Shared Storage di PT Soka Cipta Niaga
Authors: Diwangkoro Tegar Gagat
Published: February 2025

PT Soka Cipta Niaga adalah perusahaan manufaktur yang bergerak pada bidang produksi, distribusi, dan perdagangan produk industri halal seperti kaos kaki merek SOKA, masker, kerudung, manset, pakaian dalam, dan legging. Permintaan rata rata pada Tahun 2023 menunjukan angka sebesar 88.012 lusin per bulan, sedangkan kapasitas Gudang yang dimiliki PT Soka Cipta Niaga hanya sebesar 87.600, hal ini menjadi salah satu masalah yang dihadapi bagian pusat logistik Gudang PT Soka Cipta Niaga sehingga penempatan barang yang tidak tertata rapih sehingga operator memerlukan waktu yang lebih lama dalam pengambilan barang. Penelitian ini bertujuan untuk menganalisis kapasitas Gudang dengan menggunakan gabungan metode dedicated storage dan shared storage untuk memaksimalkan kapasitas penyimpanan dan pemanfaatan ruang Gudang. Penggabungan dua metode ini bertujuan untuk menyediakan sumber daya penyimpanan sesuai dengan kebutuhan yang berbeda-beda, barang yang berjenis fast moving atau membutuhkan akses cepat dapat dialokasikan ke metode dedicated storage, sementara barang berjenis slow moving atau dinamis dapat menggunakan shared storage. Hasil penelitian menunjukkan peningkatan kapasitas penyimpanan sebesar 96.000 lusin dibandingkan dengan tata letak awal yaitu hanya sebesar 87.600 lusin atau meningkat sebesar 9,59% setelah relayout. Bedasarkan rekomendasi yang diberikan kepada PT Soka Cipta Niaga yaitu bedasarkan hasil penelitian untuk mengimplementasikan tata letak Gudang yang baru untuk menghindari penumpukan artikel dalam satu pallet.
Implementasi Lean Six Sigma untuk Minimasi Pemborosan (Studi kasus di Industri Manufaktur Obat)
Authors: Kurniawan Amalia
Published: February 2025

PT X merupakan sebuah perusahaan yang bergerak di bidang industri manufaktur obat yang memproduksi beberapa produk sediaan obat seperti tablet, liquid, serbuk, kapsul, dan produk herbal. Observasi awal yang dilakukan, ditemukan keterlambatan pengiriman produk FDC2 terutama pada Bulan Januari hingga Maret 2024. Keterlambatan yang terjadi sebanyak 1-2 hari yang mengakibatkan pengiriman FDC 2 diganti dengan produk lain, sehingga membuat para karyawan harus lembur sementara Perusahaan harus mengeluarkan uang lembur untuk menyelesaikan produk tersebut. Penelitian ini dilakukan untuk melakukan analisis permasalahan keterlambatan yang terjadi dengan pendekatan Lean six sigma untuk meminimasi pemborosan. Metode Six sigma memiliki lima tahapan utama yaitu Define, Measure, Analyse, Improve, dan Control. Hasil identifikasi pada tahap Define dan Measure menunjukan bahwa waktu untuk menyelesaikan satu batch selama 65 jam, dengan nilai RTY sebesar 94,67%. Dengan menggunakan metode FMEA, diketahui nilai RPN untuk proses produksi FDC2 sebesar 50 yang artinya tingkat keparahan yang sedang. Setelah dilakukan perbaikan aktivitas dengan menghilangkan kegiatan seperti menyiapkan Batch Record dan memindahkan barang kebagian lain, maka terdapat perbaikan total persentase PCE yang sebelumnya 82,00% menjadi 82,08%, waktu siklus yang sebelumnya 7,23 strip/menit menjadi 7,80 strip/menit, lost time dari 466,53 menit menjadi 206,52 menit, dan produk hilang dari 4919 strip/menit menjadi 1689 strip/menit.
Perbaikan Kinerja Picker Gudang Finished Goods dengan Penerapan Sistem Kanban untuk Minimasi Retur di PT XYZ
Authors: Putri Sita Mustika Permata
Published: February 2025

PT XYZ yang berlokasi di Kota Cimahi memiliki produk yang dihasilkan berupa kaus kaki yang diekspor ke berbagai negara. Sistem produksi dengan tujuan On Time Delivery menjadi sasaran utama pencapaian PT XYZ dalam melangsungkan bisnisnya di kancah dunia. Latar belakang penelitian ini terletak pada aktivitas gudang finish good khususnya picker gudang yang belum memenuhi permintaan konsumen dengan tepat waktu. Pengiriman barang oleh picker gudang yang diperoleh hanya 80,77% dari keseluruhan pesanan sehingga mengakibatkan retur barang. Penelitian ini bertujuan untuk mengidentifikasi penyebab keterlambatan pengiriman yang mengakibatkan retur di PT XYZ, membuat sistem Kanban untuk mengatasi keterlambatan pengiriman dan minimasi retur serta menghitung efisiensi kinerja picker gudang setelah diterapkannya sistem Kanban. Teknik pengumpulan data dilakukan dengan observasi secara langsung terhadap picker gudang. Pengolahan data yang dilakukan yaitu dengan mengidentifikasi penyebab keterlambatan pengiriman barang menggunakan diagram fishbone, menerapkan sistem Kanban dengan mengidentifikasi aliran kanban, pos kanban, dan menentukan jumlah kanban sebagai upaya perbaikan meminimalisir keterlambatan pengiriman dan minimasi retur serta melakukan perhitungan efisiensi kinerja picker gudang berdasarkan pengukuran waktu kinerja picker. Hasil penelitian ini yaitu identifikasi penyebab keterlambatan pengiriman barang berdasarkan rangkuman Focus Group Discussion (FGD) dari diagram fishbone, diperoleh akar masalah yang perlu dilakukan perbaikan yaitu metode yang digunakan berupa proses pendataan barang secara manual diubah dengan penggunaan sistem Kanban. Berdasarkan akar masalah tersebut, dilakukan perbaikan picker gudang dengan penerapan sistem Kanban untuk mengatasi keterlambatan pengiriman dan minimasi retur. Setelah dilakukan perbaikan terhadap picker gudang, diperoleh efisiensi kinerja picker gudang yang menghasilkan persentase pengiriman sebesar 90,64% dengan peningkatan sebesar 18,41%. Hal tersebut dapat meminimalisir keterlambatan waktu pengiriman dan minimasi retur.
PENERAPAN MODEL PEMBELAJARAN NHT (NUMBERED HEAD TOGETHER) DALAM MENINGKATKAN MINAT BELAJAR PESERTA DIDIK SD
Authors: Sri Fitrianti  , Andhin Dyas Fitriani  , Asri Aulia Rachman
Published: February 2025

The NHT (Numbered Head Together) learning model is one of the many cooperative learning models. The purpose of this study is to increase students' interest in learning through the application of the NHT learning model in the classroom. This study uses the Collaborative Classroom Action Research (CAR) method. The location of the study was carried out at SDN 037 Sabang, Bandung City with the research subjects being 30 class IV-B students. This collaborative classroom action research was carried out in two learning cycles. The data collection techniques used were observation and learning interest questionnaires according to four indicators of learning interest, such as feelings of pleasure, interest, attention, and student involvement. Based on the results of the collaborative classroom action study, there was a significant increase in learning interest after the implementation of the NHT learning model in the classroom. In cycle I, it reached 13 aspects, while in cycle II it increased to 15 aspects which were summarized in 4 indicators of learning interest. Thus, the application of the NHT learning model has proven effective in increasing the learning interest of class IV students. The application of the NHT learning model is one of the real actions of improvement in the learning process, so that changes and improvements need to continue to be made in order to increase students' interest in learning so that it has an impact on their learning outcomes.
Analisis Peran Keluarga Dalam Membentuk Karakter Tanggung Jawab Siswa SD Negeri 5 Ngulak
Authors: Ria Anatasia  , Idris Muhammad , Prasrihamni Mega
Published: February 2025

This research aims to identify the role of the family in forming responsible character education in grade IV students at SD Negeri 5 Ngulak. The research method used is descriptive qualitative. The population in this study was 24 parents of students at SD Negeri 5 Ngulak. The sample used in this study was 5 parents of students and 1 homeroom teacher from students at SD Negeri 5 Ngulak. Based on research results and discussion about the influence of the family's role in shaping students' responsible character. It was found that the family has an important role in forming and encouraging the formation of students' responsible character at school. The role of the family obtained in this research is as an educator, guide, facilitator and student motivation in guiding the implementation of students' obligations at school. Apart from the role of the teacher, the role of the homeroom teacher is also important in controlling the development of students' responsible character at school by giving assignments and as a reminder if students are not disciplined in carrying out the tasks given. The final finding in this research is that the family has a very important role in forming character. student responsibility both in terms of school discipline and in carrying out assignments.
Analisis Efektivitas Penggunaan Video Pembelajaran Dalam Peningkatan Hasil Belajar Siswa Sekolah Dasar
Authors: Reza Fitriyani Sari  , Hasni Septiani  , Miftahu Rahman  , Supriyadi  , Jody Setya Hermawan
Published: February 2025

Penelitian ini bertujuan untuk menganalisis keefektifitasan penggunaan video pembelajaran dalam peningkatan hasil belajar peserta didik di sekolah dasar. Metode yang digunakan dalam penelitian ini adalah studi literatur dengan melakukan peninjauan berbagai penelitian yang berkaitan dengan topik yang dibahas serta mengkaji penelitian-penelitian terdahulu yang mempunyai kaitan terhadap penggunaan video pembelajaran dengan hasil belajar peserta didik. Dalam pengumpulan data peneliti akan menggunakan studi literatur terkait efektivitas penggunaan video pembelajaran sebagai upaya pendidik dalam meningkatkan hasil belajar peserta didik. Pencarian sumber literatur yang berkaitan dengan topik penelitian menggunakan perpustakaan digital dan database online yang dilakukan oleh peneliti. Hasil dari analisis penelitian ini menunjukkan bahwa penggunaan video pembelajaran dapat meningkatkan motivasi belajar dan hasil belajar peserta didik. Berdasarkan analisis di atas, dapat disimpulkan bahwa penggunaan video pembelajaran efektif dalam peningkatan hasil belajar peserta didik di sekolah dasar. Penggunaan video dalam proses pembelajaran membuat peserta didik dapat memahami materi yang dipelajari dengan mudah dan dipahami melalui gambar, suara dan animasi yang disajikan, sehingga dapat meningkatkan motivasi belajar dan hasil belajar peserta didik.
Peningkatan Prestasi Belajar Perubahan Energi Listrik Melalui Metode Demonstrasi dan Eksperimen Siswa Kelas VI SDN 1 Bayung Lencir Tahun Pelajaran 2024/2025
Authors: Ariyani  , Hadiyanyo  , Indryani
Published: February 2025

To create quality education in the future, education in Indonesia should pay more attention to the quality of education. For example, prioritizing teacher abilities, a good educational curriculum, then thinking about creating outstanding students. The objectives of this research are: 1) To describe the increase in student learning achievement in learning changes in electrical energy through the Demonstration and Experiment Method, 2) To find out how complete the students' learning is in learning changes in electrical energy after using the Demonstration and Experiment Method. This research uses demonstration and experimental methods with the Kemmis and Taggart model of classroom action research (PTK) approach which consists of four stages: planning, action, observation and reflection. The research was conducted at SDN 1 Bayung Lencir on 20-28 October 2024, involving 38 students (11 boys and 9 girls). Data is collected through observation, learning results tests, and documentation, then analyzed using observation techniques, evaluation of test results, and documentation. From the results of this research, it was found that student learning achievement increased from each cycle, namely cycle I 50%, and cycle II 100%. This research shows that the application of the Demonstration and Experiment Method effectively increases student learning achievement in learning about changes in electrical energy. The results show an increase in student learning completeness from 50% in cycle I to 100% in cycle II. This proves that this method is able to help students understand concepts better through direct and interactive experience. The implications of this research are good for teachers, students and schools as well as other researchers.
OPTIMALISASI PENGGUNAAN MEDIA INTERAKTIF DIGITAL DALAM PEMBELAJARAN MATEMATIKA DI SEKOLAH DASAR UNTUK MENINGKATKAN KETERLIBATAN DAN HASIL BELAJAR SISWA
Authors: Adeilla Najwa Salsabila  , Ifnur Fadhilla Legthonia  , Mellyza Azzara  , Supriyad  , Jody Setya Hermawan
Published: February 2025

This research aims to explore the application of digital interactive media in improving mathematics learning outcomes in elementary schools. The method employed is qualitative research, with data collection techniques involving a literature review of 15 peer-reviewed journal articles published between 2014 and 2024. The data is analyzed in depth to identify patterns, themes, or relationships relevant to the research topic. Data collection techniques include content analysis of articles related to the use of interactive digital media in mathematics learning. The instrument used in this study is an analysis form designed to evaluate the quality and impact of interactive media in the context of mathematics education. The analysis results indicate that the use of digital interactive media, such as educational applications and learning videos, can significantly enhance students' motivation and understanding of mathematical concepts. The use of appropriate media not only addresses students' negative perceptions of mathematics but also increases engagement and provides a more enjoyable learning experience. These findings highlight the importance of integrating technology into mathematics education to create a more effective and interactive learning process, which positively impacts students' learning outcomes.
Auge del orden colonial
Authors: Arroba Freire Mélida Estefania , Machado Gamboa Jamie Cristina
Published: February 2025

El auge del orden colonial en América Latina se estableció a través de reformas que reorganizaron la forma en que se gobernaban y se explotaban las colonias. Se intentó centralizar el poder y hacer la administración más eficiente, pero estas reformas también causaron descontento entre las élites locales, lo que impulsó movimientos por la independencia. El colonialismo no solo afectó a las colonias, sino también a las potencias europeas, creando una dinámica de dominación económica y cultural que beneficiaba a unos pocos a expensas de muchos. En la Audiencia de Quito, los españoles buscaron aprovechar al máximo la producción de metales preciosos y otros bienes. Para ello, reemplazaron el sistema de encomiendas por la mita, que obligaba a los indígenas a trabajar en diversas tareas, aunque recibían un salario. Esta situación generó desigualdades profundas en la sociedad, donde los españoles controlaban el poder, mientras que indígenas, mestizos y esclavos africanos ocupaban los niveles más bajos de la jerarquía social. Aunque los mestizos buscaban un lugar en la sociedad, no gozaban de los mismos derechos que los españoles. El Estado y la Iglesia jugaron roles importantes durante esta época. El Estado regulaba la vida cotidiana y el trabajo forzado de los indígenas, mientras que la Iglesia, en alianza con el gobierno español, promovía la educación y la cultura, al mismo tiempo que justificaba la conquista. Así, la Iglesia se convirtió en una poderosa institución en Quito, influenciando fuertemente la cultura y el arte de la región.
Substrate Temperature Dependence of Surface Morphology and Structure of N-Type Fe2O3 Thin Films With Enhanced Transparency
Authors: Sharmin Mehnaz , Podder Jiban , Hossain Khandker Saadat
Published: February 2025

This work reports the effect of substrate temperature (TS) on the structure, surface morphology, optical, and electrical properties of iron (III) oxide (Fe2O3) thin films. Fe2O3 thin films were deposited from the aqueous solution of ferric chloride hexahydrate at various TS between 573 and 773 K using the spray pyrolysis technique. In field emission scanning electron and atomic force microscopic analysis, the surface of Fe2O3 films comprised nanoparticle clusters. In X-ray diffraction analysis, Fe2O3 thin films showed a rhombohedral-hexagonal structure with the predominant orientation along (104) crystallographic plane. Crystallite size reduced from 28 to 13 nm with the increase of TS between 573 and 773 K. In UV-vis- NIR spectroscopy, the highest transmittance was found to be 76% for the film deposited at the TS of 673 K. Band gap of the film was obtained between 2.05 - 2.09 eV. The electrical resistivity of the films ranged from 2.2 ´ 105 to 9.0 ´ 105 Ω-cm. The films contained n[1]type majority carriers with carrier concentration in the order of 1018 cm-3 . Fe2O3 thin films with wide band gap, high transparency, and n-type conductivity indicate that the films are suitable for Fe2O3 in optoelectronic applications.
Bangladesh Journal of Physics, Vol. 30, Issue 1, pp. 13–22, June 2023
Studies on the Dielectric Constant, AC Electrical Conductivity and AC Electrical Modulus of V2O5 Addition Lithium-Zinc Ferrites
Authors: Islam S M Rubayatul , Shikder M Rasel , Ullah M Samir
Published: February 2025

This study investigates the electrical transport features of V2O5 added Li-Zn ferrites. The ferrites have the compositions Li0.25Zn0.50Fe2.25O4 + xV2O5 (where x = 0.4, 0.8 and 1.2 wt %) and are prepared by the solid-state reaction technique. Frequency-dependent dielectric constant and ac conductivity of the samples have been investigated at room temperature. An enhancement of dielectric constant and ac conductivity is observed with V2O5 addition and displayed a decreasing trend for higher V2O5 addition. The Nyquist impedance plots of the samples display a single semicircular arc, indicating that the conduction mechanism of Li-Zn ferrites occurs through the grain property.
Bangladesh Journal of Physics, Vol. 30, Issue 1, pp. 35-41, June 2023
Performance Evaluation of the Ge Discovery IQ PET/CT System According to the Nema NU2-2012 Standard
Authors: Mia Md Shohag , Hossain Md Nahid , Biman Tanvir Ahmed , Kabir M F Fazlul
Published: February 2025

A PET/CT Scanner -Discovery IQ 5 ring. GE Medical system was installed at Evercare Hospital Dhaka. Total of 11252 BGO crystal elements are arranged in 5 circular rings providing 260 mm axial and 700 mm trans axial field of view. The aim of the test was to assess the performances of the PET/CT scanner GE-Discovery IQ 5 ring. Spatial resolution, Image Quality, and Sensitivity tests were carried out as per NEMA NU2-2012 Standard guidelines. Spatial resolution for radial, tangential and axial directions was carried out at (x,y): (0,1), (0,10), and (0,20) cm locations. Sensitivity was calculated from the activity concentration factor. Image reconstruction algorithm VPHD was used. The radial, tangential, and axial FWHM 4.2 mm, 4.74 mm, and 4.82 mm at 1 cm; 5.72 mm, 4.82 mm, and 4.57 mm at 10 cm off center; 8.17 mm, 4.85 mm, and 4.92 mm at 10 cm off center respectively. In NEMA image quality, the hot contrast recovery values for 10-13-17-22 mm spheres were 25.7- 50.3-56.1-69.7 % respectively and cold contrast recovery values for 28 mm and 37 mm spheres were 75.5 and 77.7 % respectively; the corresponding background variability values were 7.2-6.9-6.6-5.9-5.5-4.7 %. The lung error residual mean was 16 %. Overall, PET performances of the Discovery IQ whole body scanner were satisfactory and passed the entire NEMA NU2- 2012 acceptance test.
Bangladesh Journal of Physics, Vol. 30, Issue 2, pp. 57–67, December 2023
Effect of Laser Contrast on MeV Protons From Relativistic Laser-Solid Interactions
Authors: Kakolee K F , Singh Prashant Kumar , Ter Avetisyan Sargis
Published: February 2025

Results on acceleration of MeV protons from 100 TW Ti:Sapphire laser system is presented in this paper. By irradiating few micrometers thick aluminum foils with 30 fs laser pulse with intensity of 1020 W cm-2, protons with energy exceedingly more than 10 MeV were detected. However, on increasing our laser contrast by 2 orders of magnitude (10-8 to 10-10), we observe a nearly 4.5 times enhancement in the proton flux, with a slight reduction in the proton cut-off energy. These results open a prospect of producing high flux of MeV-class proton beams.
Bangladesh Journal of Physics, Vol. 30, Issue 2, pp. 77–80, December 2023
Bhashantek Rehabilitation Project (BRP): The Rhetoric of Housing Project for the Urban Poor in Bangladesh
Authors: Khan Rasheda Rawnak
Published: February 2025

In general, this paper focuses on low-income housing, city planning and the state's intention in building a new housing project called Bhashantek Rehabilitation Project (BRP) in Dhaka, Bangladesh. In particular, it explores how BRP became a "failure" project dominated by different types of elites. Access to housing here in BRP is negotiated in the continuously changing arrangements of a complex between formal and informal rules and regulations. By focusing on this specific issue, this paper argues that the project was based on an exclusionary construction in the interactions within the project itself. It also examines how the dynamics of intermediaries further complicated the project. In addition, while acknowledging the power of the state's patronage for a particular class, such as the developer and the bureaucratic apparatus, this paper brings together many other issues on prevalent discourse on scientific city planning.
JBIP, Vol. 14, 2021, pp. 1-25
Assessing the impact of risk perception of a community on cyclone vulnerability: A case study of Pratapnagar, Satkhira
Authors: Hasanuzzaman A B M , Auroni Musarrat Zaman , Fatima Anjuman
Published: February 2025

The purpose of the article is to investigate how cyclone vulnerability is triggered by a community's sense of risk. A study on this issue was conducted in Pratapnagar, Satkhira district in southern Bangladesh. The study is focused on assessing the perception of cyclone risk, the degree of adaptation of coping mechanisms, and the disparity of losses and damage resulting from the disaster. Focus group discussions and a closed-ended questionnaire survey were used in a mixed approach of study to investigate the level of the community's perception of risk and its relation to adoption of coping mechanisms and damage. The subjects were categorized in two groups. One group had a negative propensity to risk while the other had a positive inclination. The results show a significant difference in the degree of adoption and loss between these two groups. The economic losses between these two groups were considerably different. The group with negative propensity to risk needed comparatively less resources for recovery. People become oblivious to the risk of disaster due to several factors, including prior experience, a lack of trust in early warning systems, disregard for risk, etc. These results suggest that a person's risk assessment is a critical factor in determining whether they adopt the right defences to lessen the disaster's negative effects.
JBIP,Vol. 15, 2022, pp. 13-24
Adopción homoparental vs el principio de ejercicio progresivo de derechos
Authors: Llambo-Tisalema Gonzalo , Salazar-Orozco Ricardo
Published: February 2025

Con el objetivo de contrastar criterios jurídicos para la aplicación del principio de progresividad de derechos en los procesos de adopción homoparental en Ecuador, la presente revisión bibliográfica analiza los principios legales y debates en torno al tema de adopción homoparental en Ecuador y otros países. Se hace hincapié en la importancia de considerar los principios de igualdad, no discriminación y realización progresiva de los derechos humanos en el contexto de la adopción homoparental. Se destaca la necesidad de priorizar el interés superior del niño y garantizar su bienestar y desarrollo en un entorno familiar adecuado. Se concluye que aún no existe el reconocimiento de la adopción homoparental en la legislación ecuatoriana lo que es tema de discusión. Se debería contrastar criterios jurídicos, relativos a la aplicación e interpretación del principio de progresividad de derechos de niños con relación al derecho a una familia en los distintos tipos que se reconoce en el texto constitucional. Se sugiere que la adopción de un niño por una pareja del mismo sexo debe basarse en el interés superior del niño y su derecho a un entorno familiar adecuado, y no en la orientación sexual o la identidad de género de los padres adoptivos.
La relevancia del consentimiento informado en la responsabilidad penal médica: Sistemas jurídicos en la Comunidad Andina.
Authors: Asitimbay-Márquez Mayra , Molleturo-Jiménez Julio
Published: February 2025

Este estudio analiza la importancia del consentimiento informado en la responsabilidad penal médica dentro de la Comunidad Andina, enfocándose en los sistemas jurídicos de Colombia, Perú y Bolivia. El problema radica en la diversidad de normativas sobre el consentimiento informado, que plantea desafíos para proteger los derechos del paciente y establecer responsabilidades legales  para los profesionales de salud. El objetivo es realizar un análisis comparativo de las normativas nacionales y casos judiciales, identificando diferencias y vacíos que podrían mejorar la calidad en la atención médica. Se realizó una revisión exhaustiva de literatura, sentencias judiciales y normativa comparativa regional. Los resultados subrayan cómo la ausencia o deficiencia en la información proporcionada al paciente ha resultado en sanciones judiciales y resalta la necesidad de armonización regional. La conclusión indica que un marco normativo homogéneo fortalecería la práctica médica en la región y reduciría los casos de mala praxis, garantizando los derechos del paciente.
IMPLEMENTASI BAHASA PEMPROGRAMAN PHP DAN MYSQL DALAM PERANCANGAN APLIKASI TICKET CENTER RESERVATION PO. NPM
Authors: Hardiyanti Putri Stefani , Aulia Wizra
Published: February 2025

The rapid development of information technology today significantly impacts various sectors, including business, to compete more effectively. One of the important applications of technology is the development of a web-based information system for managing bus departure schedules and ticket reservations. This research aims to design and implement a web-based ticket reservation system for PO. NPM in Bukittinggi City, in order to improve efficiency and address data redundancy issues that occurred in the previous manual system. The system design method used is the Waterfall method. This system is built using PHP as the server-side programming language and MySQL as the database to store ticket reservation data and bus departure schedules. The result of this research is a web-based ticket reservation system that allows passengers to book tickets online without having to visit the ticket counter. The implementation of the web-based information system at PO. NPM can improve passenger comfort, operational efficiency, and better data management. This system also contributes to improving service quality and reducing the potential for errors in data processing.
IMPLEMENTASI MODEL DeiT UNTUK MEMBEDAKAN GAMBAR BUATAN AI DAN MANUSIA PADA ILUSTRASI ANIMASI 2D
Authors: Erwin Ibnu Taimiyah , Abdul Latief Arda  , Imran Taufik  , Muhammad Erwin Rosyadi. S  , Hilyatul Auliyah Erwin
Published: February 2025

The development of artificial intelligence (AI) has influenced various fields, including art and visual design. AI Generative Art, which mimics human styles, has sparked debates on originality, artistic value, as well as legal and ethical challenges. Therefore, methods are needed to distinguish between AI-generated and human-made images, particularly in 2D animation illustrations. This study proposes the use of Data-efficient Image Transformers (DeiT) for image classification. Two models tested are DeiT Base and DeiT Tiny, using a dataset of 6,000 images equally divided between AI and human categories. The dataset is split into training (70%), validation (15%), and testing (15%). Experimental results show that DeiT Base achieves over 95% accuracy with fast convergence and optimal loss function stability. Meanwhile, DeiT Tiny attains around 93% accuracy, being more computationally efficient despite requiring more epochs for stability. Compared to previous models using a larger dataset (11,000 images per category) but achieving only 80% accuracy, DeiT performs better in both accuracy and computational efficiency, even with a smaller dataset. In conclusion, DeiT is effective for classifying 2D animation images. DeiT Base excels in accuracy and convergence speed, while DeiT Tiny is more resource-efficient, making it an ideal choice for environments with computational constraints.
The Current State of Effectiveness of the Security System of the Slovak Republic
Authors: Miňová Katarína
Published: February 2025

The objective of this article is to analyze the current state of the Slovak Republic's security system, with a particular focus on its effectiveness and the role of the Security Council of the Slovak Republic within the crisis management framework. The paper examines the legislative and organizational aspects of the security system, emphasizing its capacity to
respond to contemporary challenges such as hybrid and cyber threats. Using a SWOT analysis, the study identifies strengths, weaknesses, opportunities, and threats, while comparing Slovak practices with those of other Visegrad Group countries, particularly the Czech Republic and Poland. Examples from crisis management during the COVID-19 pandemic and other emergencies illustrate the practical implications of the system's operations. Based on these findings, the article proposes recommendations for enhancing the system's coordination, digitalization, and resilience, offering a framework for more efficient crisis response at national, regional, and local levels.
PARADOXES OF GRAVITY: Newton's Law Does Not Work at Large Distances, but... it's too early to throw it in the scrapheap.
Authors: Kosinov Mykola
Published: February 2025

The dominant force in the Universe is gravity. For over 300 years, the gravitational force was represented by a single simple and mathematically perfect formula - Newton's law of gravity FN = GmM/r^2. However, the boundaries of its applicability are limited to the solar system. The revealed gravitational anomalies in the dynamics of stars show that at large distances, Newton's law is not satisfied and has significant discrepancies with observations. The real law of gravity is more complex than Newton's law. For large distances and large masses, the gravitational force dominates in the Universe, which Newton's law "does not see". A new law of gravity Fcos = (mc^2)√Ʌ was obtained, which shows the cosmological force not taken into account by Newton's law. Two laws of gravity (Newton's law + the law of cosmological force) provide a complete description of the gravitational interaction in the Universe.
Non-contact ultrasound testing of batteries
Authors: Herterich James , Allwright David , Bearup Daniel , Kombrink Sabrina , Herring Daniel , Liu Zhixuan , Wu Zipeng , Olesker-Taylor Sam
Published: February 2025

Hy-Met are a company using ultrasound for non-destructive testing of batteries. These ultrasound signals contain information on the health of a battery. Hy-Met aim to understand real acoustic data. However, data for particular defects is scarce. The challenge is to understand the reflection and transmission of ultrasound signals within the layers of battery, especially with defects present in certain regions of the battery. In this report, we seek to (i) understand properties of current models, (ii) apply data analysis techniques to extract relevant features from real data, (iii) understand reflection and transmission via probabilistic and combinatorial models. These may lead to the generation of synthetic data for further analysis and training.
PENGARUH NILAI SOSIAL, PENGHARGAAN FINANSIAL DAN PERTIMBANGAN PASAR KERJA TERHADAP MINAT MAHASISWA DALAM PEMILIHAN KARIER SEBAGAI AUDITOR
Authors: Meliawati Meliawati , Prima Argo Putra
Published: February 2025

ABSTRAK
Perkembangan globalisasi dan teknologi yang pesat saat ini telah membawa dampak signifikan terhadap dunia bisnis, sehingga memicu kemajuan dan pertumbuhan. Pilihan karier mahasiswa, khususnya sebagai seorang auditor, memiliki dampak signifikan pada masa depan pribadi mereka dan juga pertumbuhan industri di Kota Batam. Penelitian ini bertujuan untuk menggali hubungan nilai sosial, penghargaan finansial, dan pertimbangan pasar kerja terhadap minat mahasiswa dalam pemilihan karier sebagai auditor. Metode penelitian ini menggunakan metode penelitian kuantitatif. Penelitian ini mendapatkan hasil bahwa nilai sosial dan penghargaan finansial berpengaruh positif dan signifikan terhadap minat mahasiswa dalam pemilihan karier sebagai auditor, kemudian untuk variable pertimbangan pasar kerja berpengaruh negatif dan tidak signifikan terhadap minat mahasiswa dalam pemilihan karier sebagai auditor. Penelitian ini diharapkan dapat memberikan pemahaman yang lebih komprehensif terkait kurangnya jumlah auditor di Batam.
Kata Kunci :  Nilai Sosial, Penghargaan Finansial, Pertimbangan Pasar Kerja  dan Minat.
Induced mesenchymal stem cells generated from periodontal ligament fibroblast for regenerative therapy
Authors: Vembuli Hemanathan , Rajasingh Sheeja , Nabholz Patrick , Guenther Jefferson , Morrow Brian R. , Taylor Margaret M. , Aghazadeh Marziyeh , Sigamani Vinoth , Rajasingh Johnson
Published: February 2025

Bone fractures and bone loss represent significant global health challenges, with their incidence rising due to an aging population. Despite autologous bone grafts remain the gold standard for treatment, challenges such as limited bone availability, immune reactions, and the risk of infectious disease transmission have driven the search for alternative cell-based therapies for bone regeneration. Stem cells derived from oral tissues and umbilical cord mesenchymal stem cells (MSCs) have shown potential in both preclinical and clinical studies for bone tissue regeneration. However, their limited differentiation capacity and wound healing abilities necessitate the exploration of alternative cell sources. In this study, we generated induced pluripotent stem cells (iPSCs) using a safe, nonviral and mRNA-based approach from human periodontal ligament fibroblasts (PDLF), an easily accessible cell source. These iPSCs were subsequently differentiated into MSCs, referred to as induced MSCs (iMSCs). The resulting iMSCs were homogeneous, highly proliferative, and possessed anti-inflammatory properties, suggesting their potential as a superior alternative to traditional MSCs for regenerative therapy. These iMSCs demonstrated trilineage differentiation potential, giving rise to osteocytes, chondrocytes, and adipocytes. The iMSC-derived osteocytes (iOSTs) were homogeneous, patient-specific and showed excellent attachment and growth on commercial collagen-based membranes, highlighting their suitability for bone tissue regeneration applications. Given their promising characteristics compared to traditional MSCs, PDLF-derived iMSCs are strong candidates for future clinical studies in bone regeneration and other regenerative dental therapies.
EUFOREA meeting on defining disease states in allergic rhinitis: towards a unified language in AR
Authors: Scadding G. K. , Conti D. M. , Scheire S. , Backer V. , Blaiss M. , Cardell L. O. , De Yun W. , Ellis A. K. , Fokkens W. , Fox A. T. , Gilbert Kruz T. , Halken S. , Hellings P. W. , Hox V. , Kalogjera L. , Lau S. , Marinho S. , McDonald M. , Mösges R. , Mullol J. , Nasser S. , Pawankar R. , Price D. , Ryan D. , Scadding G. , Smith P. , Sosa Kostrábová M. , Vazquez-Ortiz M. , Wahn U. , Zhang L. , Gevaert P.
Published: February 2025

Allergic rhinitis (AR), the most prevalent immunological disease, affects approximately 400 million individuals globally and can significantly impact quality of life (QoL). Despite nearly 25 years of guidelines, AR remains largely under- diagnosed, suboptimally treated and poorly controlled. In the light of new knowledge and treatment options, there is a necessity to update or revise fundamental AR definitions to facilitate communication across diverse specialties engaged in its treatment and to improve patient care. The European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA) convened a meeting of experts and patient representatives to deliberate the optimal methodology for measuring AR treatment responses and establishing novel treatment goals. This paper presents a consensus on revised AR definitions, including control, severe allergic rhinoconjunctivitis (SARC), refractory severe allergic rhinoconjunctivitis (R-SARC), remission, resolution, improvement, exacerbation, treatable traits (TTs), treat to target, relapse, progression, disease modification, and prevention.
Experimental investigation on the reverse mechano-electrical effect of porcine articular cartilage
Authors: Liu Chunsheng , Zhao Le , Dong Hao , Hua Zekun , Wang Yanqin , Wang Yongxing , Li Pengcui , Wei Xiaochun , Zhang Kai , Xue Yanru , Wu Xiaogang , Chen Weiyi
Published: February 2025

Introduction

The electric signals within the cartilage tissue are essential to biological systems and play a significant role in cartilage regeneration. Therefore, this study analyzed and investigated the reverse mechano-electrical effect in porcine articular cartilage and its related influencing factors.

Methods

The deflection of cartilage samples in an electric field was measured to analyze the mechanisms of different factors affecting the reverse mechano-electrical effect in articular cartilage.

Results

The results showed that the cartilage thickness, water content, and externally applied voltage all impacted the deflection of the cartilage. The reduction in cartilage water content resulted in a decrease in cartilage thickness, following the same influencing mechanism as thickness. On the other hand, an increase in the externally applied voltage led to an increase in the electric field force within the cartilage space, consequently increasing the deflection of the cartilage in the electric field. Additionally, the externally applied voltage also caused a slight temperature rise in the vicinity of the cartilage specimens, and the magnitude of the temperature increase was proportional to the externally applied voltage.

Discussion

The fitting results of the experimental data indicated that cartilage thickness influenced the dielectric constant and moment of inertia of the cartilage in the electric field, thereby affecting the magnitude of the electric field force and deflection of the cartilage. This may provide valuable insights for further investigation into the microscopic mechanisms of cell proliferation, differentiation, and cartilage regeneration induced by electrical stimulation.
Exploring the associations of gut microbiota with inflammatory and the early hematoma expansion in intracerebral hemorrhage: from change to potential therapeutic objectives
Authors: Jiang Haixiao , Zeng Wei , Zhu Fei , Zhang Xiaoli , Cao Demao , Peng Aijun , Wang Hongsheng
Published: February 2025

Background

Although a great deal of research has explored the possibility of a systemic inflammatory response and dysbiosis of the gut microbiota after an intracerebral hemorrhage (ICH), the relationships between gut microbiota and blood inflammatory indicators as well as their role in the hematoma expansion following an early-stage mild-to-moderate ICH (emICH) remain unknown. This study analyzes these changes and associations in order to predict and prevent hematoma expansion after emICH.

Methods

The study included 100 participants, with 70 individuals diagnosed with emICH (30 with hematoma expansion and 40 without hematoma expansion, referred to as the HE and NE groups) and 30 healthy controls matched in terms of age and gender (HC). We used 16S rRNA gene sequencing to explore the gut microbial structure and its underlying associations with blood inflammatory parameters in the HE group.

Results

Our findings showed a significant decrease in the diversity and even distribution of microorganisms in the HE group when compared to the HC and NE groups. The composition of the gut microbiota experienced notable alterations in the emICH group, especially in HE. These changes included a rise in the number of gram-negative pro-inflammatory bacteria and a decline in the level of probiotics. Furthermore, we observed strong positive connections between bacteria enriched in the HE group and levels of systemic inflammation. Several microbial biomarkers (e.g. Escherichia_Shigella, Enterobacter, and Porphyromonas) were revealed in disparateiating HE from HC and NE. Analysis of the Kyoto Encyclopedia of Genes and Genomes (KEGG) exposed disturbances in essential physiological pathways, especially those related to inflammation (such as the Toll-like receptor signaling pathway), in the HE group.

Conclusions

Our exploration indicated that individuals with emICH, especially those with HE, demonstrate notably different host-microbe interactions when compared to healthy individuals. We deduced that emICH could rapidly trigger the dysbiosis of intestinal flora, and the disturbed microbiota could, in turn, exacerbate inflammatory response and increase the risk of hematoma expansion. Our comprehensive research revealed the potential of intestinal flora as a potent diagnostic tool, emphasizing its significance as a preventive target for HE.
Unusual hypertrophic cardiomyopathy: case report of an early onset wild-type ATTR amyloidosis accompanied by a chromosomal duplication involving the MYH6 and MYH7 gene
Authors: Hamidi Jassin , Hanel Yvonne , Dittmann Sven , Gerding Wanda Maria , Nguyen Huu Phuc , Klingel Karin , Schulze-Bahr Eric
Published: February 2025

Background

Hypertrophic cardiomyopathy (HCM) is characterized by an increased left ventricular (LV) wall thickness and LV mass. With an estimated prevalence of 1:200–500, HCM is among the most common genetically determined cardiac diseases. Functionally, enhanced tissue stiffness and reduced elasticity, combined with diastolic dysfunction and myocardial fibrosis, can eventually lead to life-threatening arrhythmias and impaired blood flow through the heart chamber. Typical symptoms associated with HCM include atrial fibrillation (AF), syncope, ventricular fibrillation, and cardiac arrest. At the molecular level, various genetic and/or non-genetic etiologies can lead to HCM.

Case summary

In this case, we report on a 60-year-old male patient with severe, progressive hypertrophic cardiomyopathy (HCM) in an uncommon and ambivalent setting. Right ventricular (RV) biopsy and multi-phase skeletal scintigraphy diagnosed transthyretin amyloidosis with cardiac involvement. Sanger sequencing of the transthyretin gene revealed a wild-type sequence. Phenotypically, the patient initially presented with syncopal episodes, atrioventricular (AV) block, and atrial fibrillation. Subsequently, bilateral carpal tunnel syndrome and polyneuropathy developed. However, the progressive and early onset of left ventricular hypertrophy did not align with the typical presentation of HCM in the context of ATTR. Therefore, next-generation sequencing (NGS) analysis revealed a rare chromosomal duplication in both cardiac myosin genes, MYH6 and MYH7. Consequently, two distinct and rare disease entities co-occurred in this patient, both ultimately leading to HCM.

Discussion

To date, no other case featuring wild-type transthyretin amyloidosis (wtATTR) concurrently with a chromosomal duplication affecting both cardiac myosin heavy chain genes has been reported in the literature. This highlights the extreme rarity of this condition, making it challenging to ascertain the extent to which a presumably mutated hybrid myosin gene construct or the TTR amyloid fibrils contribute to stiffness, tissue fibrosis, and cardiac dysfunction. Ultimately, both effects converged in this case, leading to the same cardiac disease with an exacerbated phenotypical outcome of hypertrophic cardiomyopathy (HCM). While early onset wtATTR is an uncommon clinical finding, another significant clinical condition was identified in this patient, marked by an unusual copy number variation (CNV) in the genes MYH6 and MYH7.
Thyroid disorders and inflammatory bowel disease: an association present in adults but also in children and adolescents
Authors: Calcaterra Valeria , Penagini Francesca , Rossi Virginia , Abbattista Luisa , Bianchi Alice , Turzi Massimiliano , Cococcioni Lucia , Zuccotti Gianvincenzo
Published: February 2025

Inflammatory bowel diseases (IBD) represent chronic inflammatory multisystemic disorders that primarily involve the gastrointestinal tract. Patients with ulcerative colitis (UC) and Crohn’s disease (CD) exhibit a higher prevalence of thyroid disorders compared to the general population. The aim of this review is to summarize the literature on concomitant IBD and thyroid disorders, specifically autoimmune thyroid diseases such as Graves’ disease (GD) and Hashimoto’s thyroiditis (HT), as well as thyroid cancer, with a focus on children and adolescents. We provide an overview of the age-related differences between children and adults in the prevalence of this association. Literature shows that relatively few studies have been conducted on this subject in pediatric populations. The etiopathogenetic similarities between IBD and autoimmune thyroiditis are undeniable. Nevertheless, current data does not indicate a unanimous association between GD and HT and chronic IBD (both CD and UC). Although evidence suggests a potential association between IBD and thyroid cancer, particularly papillary thyroid cancer, the precise nature of this relationship varies across studies and is influenced by multiple factors. The limited information regarding the relationship between IBD and thyroid disorders in children highlights a significant knowledge gap. Since the thyroid plays a critical role in the pediatric population’s development, it is essential to promptly recognize and treat thyroid diseases. A thyroid function monitoring and future research exploring the genetic and immunologic connections are essential to enhance our understanding of the interrelation between IBD and thyroid disorders.