bluuebunny/crossref_metadata_2025 huggingface dataset:
Flexicurity: Panel Data Analysis for OECD Countries
Authors: Yazar Aslan Berna
Published: December 2024

This study examines the changes occurring as a result of the changes in modern labor markets and technological developments with panel data analysis for the member countries of the Organization for Economic Development and Cooperation (OECD). Flexibility policy components by the European Commission are grouped under four main headings: flexible and reliable contract arrangements, lifelong learning, effective labor market policies, and modern social security system. Indicators of these policy components have been determined to monitor and evaluate the policies implemented, as each country adopts different flexicurity strategies. Using at least one indicator for each component, a data set of 35 OECD countries for the period 2008-2017 was created. The effects of flexicurity practices on the general unemployment rate, youth unemployment rate, long-term unemployment rate, and general employment rate, which are among the main indicators of the labor market, were estimated with panel data analysis models. According to the results of the estimates, it can be said that the increase in the strictness of the legislation regarding the protection of employment, especially temporary employment, causes the unemployment rates to remain high while decreasing the employment rate. The relatively flexible implementation of the legislation to protect the labor force, the increase in spending on lifelong learning and modern social security practices stand out as factors that support the decrease in unemployment rates and the increase in the employment rate.
Estimation of Safe Operating Area for EV Battery
Authors: Kamboj Rahul Kumar , Singh Mukesh , Singh Ashima
Published: December 2024

In recent times, electric vehicles (EVs) have experienced battery pack failures dueto various factors such as short circuits, thermal imbalances, fires, and explosions.This research paper employs a machine-learning approach to estimate lithium-ion batteries safe operating area (SOA). It explores the factors that influencebattery safety levels and discusses the safe operating area for charging and dis-charging based on real-time data. The SOA concept is a critical consideration inthe design, operation, and management of EV batteries, as it defines the limitswithin which the battery can operate safely without compromising performanceor endangering the vehicle. The significance of SOA analysis for EV batteriesand its implications on battery design, thermal management, charging strate-gies, and overall vehicle safety. This paper specifically addresses the estimationof the safe operation of a battery using ML in relation to voltage and temper-ature with respect to time. It emphasises the importance of understanding theinterplay between these parameters to establish safe operational limits.
Three-Dimensional Surface Topography Analysis of Die Sinking Electrical Discharge Machined Eco-friendly Beryllium Free Cu Alloys
Authors: VIJAYAN VIPIN , SAJU KAIPRAPPADY KUNCHU , SUNDARESAN JITHIN
Published: December 2024

Beryllium-free Cu alloys, such as Copper-Nickel-Silicon-Chromium (Cu-Ni-Si-Cr) alloys, are utilised extensively in diverse sectors such as the electrical, electronics, instrument, metallurgy, aerospace, automotive, petrochemical, machinery manufacturing, and die and mould-making industries. Due to their high strength and hardness, these alloys are often fabricated into components for the above-mentioned industries using unconventional machining techniques like electrical discharge machining (EDM). EDM is particularly advantageous in industrial applications where precisely controlled random surface textures on these alloys are required. However, despite the industrial significance, experimental investigations into the EDM process of Cu-Ni-Si-Cr alloys are scarce. Therefore, the current work aims to address this research gap by conducting an experimental investigation of the random surfaces generated on Cu-Ni-Si-Cr alloy components after the die-sinking EDM process, utilising a comprehensive three-dimensional (3D) surface topography analysis. This work investigates the effects of input factors such as the electrode material, dielectric fluid material, flushing condition, and current on nearly all relevant areal texture (3D) parameters. The regression analyses reveal that current is the most significant input parameter for most areal texture parameters, followed by dielectric fluid and electrode materials. The flushing condition had minimal effect, marking a new direction for future research. The significance of each areal texture parameter was discussed from an application point of view, highlighting the potential impact of the findings.
Complete Pathologic Response (pT0) of High-Grade Upper Tract Urothelial Carcinoma to Percutaneous Cryoablation: Case Report and Review of the Literature
Authors: Friedman Brett J. , Gonsalves Cathy , Falzarano Sara M. , Joseph Jason P. , Su Li-Ming
Published: December 2024

Background
Upper tract urothelial carcinoma (UTUC) is a rare among all urologic cancers. Both UTUC and renal cell carcinoma (RCC) can present as a solid mass renal mass on imaging. Based upon current guidelines, small parenchymal-based renal mass suspected to be RCC may be monitored, thermally ablated, or surgically removed. In contrast, cryoablation is not considered a standard of care for a UTUC. Our case is of a renal parenchymal-based mass suspected to be RCC that was treated by percutaneous cryoablation, only later to find that the mass was UTUC on concurrent diagnostic needle biopsy. Subsequent completion nephroureterectomy demonstrated no residual viable UTUC in the kidney, only ghost tumor cells with reactive changes in the cryoablation site.
Case Presentation
A 67-year-old female presented to the emergency department for workup of gross hematuria. Cystoscopy revealed no intravesical lesions. CT scans revealed a 2.5 cm, well circumscribed left upper pole endophytic renal mass with no obvious collecting system involvement, concerning for RCC. Given the options of surveillance, percutaneous ablation or partial nephrectomy for a presumed RCC, the patient opted to proceed with cryoablation. Needle biopsy obtained at time of cryoablation later returned as high-grade papillary UTUC. Repeat imaging with CT IVP and CT Chest showed post-cryoablation changes without evidence of residual tumor or metastatic disease. About six weeks after cryoablation, the patient opted to undergo a completion robotic-assisted laparoscopic left nephroureterectomy, regional lymphadenectomy, and instillation of intravesical gemcitabine. Pathology of the left kidney, ureter, bladder cuff and 17 para-aortic lymph nodes demonstrated no viable UTUC (pT0N0).
Conclusions
We present the first documented case of a small unexpected UTUC with complete pathologic response to cryoablation treatment. For high-grade UTUC, nephroureterectomy remains the consensus recommendation from the National Comprehensive Cancer Network, American Urological Association, and European Association of Urology. Currently, cryoablation has no proven role in the treatment algorithm for UTUC. However, a handful of case reports and one active phase II trial suggest further investigation may be warranted into the potential role of cryoablation in the treatment of select cases of UTUC.
Genetic characterization of Mycoplasma pneumoniae in patients using clinical metagenomic next-generation sequencing data
Authors: Yang Xiaoxia , Dai Xiaoqing , Li Zhenzhen , Shui Xiaochuan , Huang Shaojun
Published: December 2024

Backgroud: This study aimed to utilize clinical metagenomic next-generation sequencing (mNGS) data to analyze the genomic characteristics of Mycoplasma pneumoniae (M. pneumoniae), thereby providing guidance for disease surveillance, prevention and control.
Methods: Clinical samples were sequenced and subjected to mNGS on a MGISEQ-200 sequencer platform using 50bp single-end (SE50) mode. The metagenomic data of samples identified with M. pneumoniae infection (sequence coverage >90%) were de novo assembled for genome comparison, molecular typing and phylogenetic analysis.
Results: Of the three genomes de novo assembled, two with high-quality sequences were analyzed. Genome comparison indicated that the inconsistent regions of the genome were mainly located on the repetitive DNA elements of M. pneumoniae. Genotyping revealed that the two characterized samples, one belonged to ST3 (P1 type 1), while the other was typed to ST7 (P1 type 2). In addition, the phylogenetic tree was constructed successfully with credible bootstrap values.
Conclusion: The clinical mNGS using SE50 strategy could be used for M. pneumoniae detection in patients with low cost and short turnaround time. Meanwhile, the sequencing data could be used for genotyping and genetic characterization of M. pneumoniae as well if the sequence coverage and depth were high enough.
Effectiveness of psychiatric support for complicated grief among a cohort of relatives of deceased patients in intensive care unit during the French Covid-19 lockdown – the OLAF (Opération Liaison et Aide aux Familles)
Authors: Raymond Valentin , Aïtout Camille , Ducos Guillaume , Coullomb Alexis , Ferré Fabrice , Riu-Poulenc Béatrice , Seguin Thierry , Boukhatem Leïla , Geeraerts Thomas , Minville Vincent , Fourcade Olivier , Vardon-Bounes Fanny , Arbus Christophe , Birmes Philippe , Silva Stein , Salles Juliette
Published: December 2024

Introduction: The death of a relative after an intensive care unit stay can lead to mental disorders as post-traumatic stress disorder or complicated grief. During the first SARS-CoV-2 lockdown in France, social restrictions limited the opportunity to apply family-centered care in intensive care unit, increasing the risk of post-traumatic stress disorder or complicated grief.Methods The psychiatric and other intensive care unit teams at Toulouse University Hospital, France, have created a temporary service known as OLAF (Opération de Liaison et d’Aide aux Familles). OLAF provided psychological phone support to family members of intensive care unit patients. Then, we investigated the impact of the OLAF service on complicated grief, comparing the prevalence of 12-month complicated grief after death in two groups: relatives provided with support via the OLAF service and a control group (standard of care).Results Of the twenty-five bereaved family members recruited, five (20%) presented with complicated grief at twelve months. The groups had no difference on complicated grief diagnosis. An explanatory model found that complicated grief symptoms intensity was mainly explained by post traumatic disorder symptoms intensity (R2 = 0.73, p = 6.21e− 05*). As the only factor significantly associated with complicated grief intensity, we found a predictive value of post-traumatic stress disorder score on complicated grief diagnosis at twelve months in a ROC curve model.Conclusion There was no difference in the prevalence of complicated grief with OLAF service. Failing to prove its effectiveness, we found post-traumatic stress disorder symptoms intensity on the PTSD Checklist for DSM-5 (PCL-5) as the only factor associated to complicated grief in our cohort. We found that this scale could also predict the complicated grief risk at twelve months.Trial registration: The study was approved by our ethics board (CPP 2020-54, ClinicalTrials.gov, Identifier: NCT04470869), and all participants provided informed oral consent.
Give the “Little Double” A Little Bit More Time ----Discussion on Delayed-Interval Delivery of the Twin: A Case Report
Authors: Zhang Yanxin , Fu Xinlu , Gu Yingyan , Lu Dan
Published: December 2024

Background
To explore the diagnosis and clinical management of delayed-interval delivery of the twin and the near- and long-term outcomes of mother and fetus.
Case presentation
A 31-year-old pregnant woman was admitted to the hospital on March 23, 2022 due to “28 weeks of menopause with spontaneous vaginal discharge of tissue for 2 hours”. On March 26, 2022 a stillborn fetus was delivered. After delivering a stillborn fetus, the patient was immediately given high ligation of the umbilical cord, antibiotics to prevent infection, atosiban to inhibit contractions, magnesium sulfate to protect the fetal cerebral nerves, and hospitalized to closely monitor the condition of the mother and the other fetus, successfully delivering a baby girl vaginally at 34 + 2 weeks, and no significant complications have been observed in both mother and baby by the two-year follow-up.
Conclusion
Delayed-interval delivery of the twin(DIDT) is a specific complication of twin pregnancies, and proper clinical management can improve the survival of the second fetus. Delayed-interval delivery(DID) may effectively prolongs the gestational age of the delivered fetus and reduces neonatal morbidity and mortality after birth.
An 18-Year Comprehensive Safety Study on Microfocused Ultrasound and Monopolar Radiofrequency Combined with Cosmetic Injectables in 1,040 Patients
Authors: Suh Dong Hye , Chen Li-Chi , Chung Hye Jin , Lee Sang Jun , Kim Jihee
Published: December 2024

Microfocused ultrasound (MFU) and (MRF) are non-invasive modalities widely used for skin rejuvenation and are often combined with injectables, including neuromodulators and soft tissue fillers. However, large-scale, long-term safety data on such combination therapies are lacking. To address this gap, we conducted a retrospective chart review at two private practice dermatology clinics in South Korea from June 2005 to December 2023. A total of 1,040 patients were included, comprising 515 (49.5%) and 525 (50.5%) patients undergoing MFU and MRF, respectively. Regarding combination therapy, the patients received neuromodulators (76.9%) or dermal filler injections using hyaluronic acid (HA) (17.3%) or poly-L-lactic acid (PLLA) (5.8%) in conjunction with MFU/MRF. Documented adverse events included one case of paradoxical bulging and three cases of eyelid ptosis among those treated with MFU/MRF and neuromodulators (overall incidence: 0.1% and 0.4%, respectively), two cases of surface irregularity among those treated with MFU/MRF and HA fillers (overall incidence: 1.1%), and one case of cheek asymmetry among those treated with MFU/MRF and PLLA injections (overall incidence: 1.7%). No adverse events such as necrosis, burns, filler migration, or unexpected premature loss of filler were reported. While limited by its retrospective design and the inclusion of only two dermatology clinics, which restricts the generalizability of the findings, our study highlights the favorable long-term safety profile of combining MFU and MRF with cosmetic injectables. Our study offers reassurance to clinicians and patients considering these approaches.
Additive-Specific Influences on Non-Classical Nucleation Pathways in Industrially Relevant Minerals
Authors: Driessche Alexander Van , Baken Annet , Fernandez-Martinez Alejandro , Lanson Martine , Aretxabaleta Xabier , Manzano Hegoi , Kellermeier Matthias , Michel Marco Di
Published: December 2024

Additives, comprising small quantities of organic and inorganic molecules, are crucial for controlling the crystallization of various (bio)materials; however, their mechanisms remain poorly understood. By integrating in situ high-energy X-ray scattering with potentiometric titrations, we examined the impact of industrially relevant additives on the nucleation pathways of portlandite and gypsum. While both minerals undergo multistep nucleation, portlandite transitions gradually from a disordered to an ordered phase, whereas gypsum exhibits an abrupt transition. These distinct non-classical pathways and their pH conditions correlate with the mineral-specific effects of the additives. Notably, additive effects extend beyond the classical models, such as cation-binding, exerting influence primarily during the prenucleation stage. Moreover, additives demonstrate a dual role by simultaneously delaying and accelerating different stages of nucleation, highlighting their multifaceted impact on the crystallization process. These findings offer valuable insights for designing tailored additives to optimize industrial crystallization processes and advance the understanding of biomineralization mechanisms.
Assessment of groundwater potential over the Haryana region: GIS-AHP v/s field data
Authors: Nagal Balbir , Prabhakar Ajay Krishna , Pal Mahesh
Published: December 2024

This study aims to delineate groundwater potential (GWP) zones of the Haryana state, India, using geospatial techniques for the year 2023. In this, multiple thematic layers created and integrated through geographic information system (GIS) and the analytical hierarchy process (AHP). The data utilized in this research were collected from multiple sources, including the shuttle radar topography mission (SRTM), Sentinel-2 satellite imagery, the food and agriculture organisation (FAO), and the India meteorological department (IMD). Thematic layers including slope, land use/land cover (LULC), soil, geology, drainage density, and lineament density, were created and weighted through the AHP. The layers were subsequently integrated through the weighted overlay analysis (WOA) method to create a GWP map for the area. This GWP map of the year 2023 was compared utilizing groundwater level (GWL) data of the year 2018 from the Central Ground Water Board (CGWB), resulting in a similarity rate of 77.55%. The results indicate that the moderate GWP zone covers 3.71% of the study area, followed by the high GWP zone, which covers 33.24% of the study area. Very high GWP covers only 11.96% of the region. The low and very low GWP zones encompass 7.59% and 3.51%, respectively. The results show that most of the territory has moderate to high GWP, with minor areas having low or extremely low potential. This shows the efficacy of GIS-AHP methods in identifying GWP zones and serves as a crucial instrument for the management of water resources in arid regions such as Haryana.
Impact of a Targeted Arab Board of Emergency Medicine Examination Preparation Courses on Resident Success Rates
Authors: Anjum shahzad , Bashir Khalid , Iftikhar Haris , Gafoor Biju , Umar Aftab Mohammed
Published: December 2024

Background
The Arab Board of Emergency Medicine (ABEM) examination is a critical milestone for Emergency Medicine Residents (EMRs) seeking to establish independent practice. To support their preparation, a five-day evening course, designed in accordance with ABEM requirements, was developed. The course, taught by ABEM-certified faculty, delivered updated and essential knowledge. This study aimed to evaluate the impact of the course on EMRs' success rates in the ABEM examination over the period from 2017 to 2021.
Methods
A five-day in-person course was conducted annually during the evenings to accommodate the schedules of both EMRs and faculty. The courses were scheduled approximately six weeks prior to the ABEM examination. The course content was carefully designed to align with ABEM examination standards, with a focus on contemporary and pertinent knowledge. EMRs underwent rigorous assessments under conditions similar to those of the ABEM examination, using standardized assessment rubrics. ABEM examination pass rates obtained from the official website were compared with historical data, and demographic variables were thoroughly analyzed.
Results
Data were collected and analyzed over five years (2017–2021). All 49 EMRs (100%) attended the course. The majority were male (69.4%). The cohort represented graduates from various regions, with notable proportions from Sudan (22.4%) and Pakistan (18.4%). The overall pass rate for the ABEM examination significantly increased to 91.8% compared with the precourse rate of 60%. The analysis indicated that variables such as gender, region or country of graduation, year of participation, and initial confidence levels did not significantly influence outcomes.
Conclusion
The findings highlight the significant impact of a face-to-face five-day ABEM examination preparation course on EMR pass rates, potentially setting a standard for similar programs in other specialties. The results emphasize the importance of targeted, contemporary instruction in improving the confidence and success of EMRs in ABEM examinations.
Machine Learning Identification of TSPAN7 as a Key Target Linking Type 2 Diabetes Mellitus and Colorectal Cancer
Authors: Yu Feng , Yang Shuixia , Dong Yan
Published: December 2024

Background
Type 2 Diabetes Mellitus (T2DM) and Colorectal Cancer (CRC) are significant global public health challenges with a notable epidemiological association. This study aims to explore the molecular mechanism behind this epidemiological association.
Methods
Weighted Gene Co-expression Network Analysis (WGCNA) and differential expression gene (DEG) analysis were conducted to identify shared genes between T2DM and CRC. Machine learning algorithms, including LASSO, Random Forest, and Support Vector Machine (SVM), were employed to identify hub genes. IOBR and clusterProfiler packages were used for immunoinfiltration assessment and enrichment analysis, respectively.
Results
We identified 27 shared genes between T2DM and CRC, with TSPAN7 emerging as a key hub gene linking the two conditions. TSPAN7 expression was significantly lower in disease groups compared to control groups across multiple cohorts, demonstrating excellent diagnostic accuracy. Enrichment analysis revealed involvement of these genes in various metabolic activities and pathways, including sulfur metabolism, selenium metabolism, renin secretion, pantothenate and CoA biosynthesis, TRP channel regulation, and efferocytosis.
Conclusion
This study provides new insights into the mechanisms underlying the association between T2DM and CRC by identifying TSPAN7 as a key target. The findings offer theoretical evidence for developing new diagnostic markers and therapeutic strategies for these diseases.
Green-Synthesis of MgO and ZrO 2 Nanocomposite: Physicochemical Properties and Anti- Plasmodial Activity in a Mouse Model
Authors: Daniel Augustine Innalegwu , Onogwu Sarah Udenyi , Gara Theresa Yebo , Oladunni Amuda , Tijani Jimoh Oladejo , Oselusi Samson Olaitan , Hussein Samad , Garba Hazeezah Mustapha , Salaudeen Aminat Oluwatoyin , Ameh Alechine Emmanuel , Keyster Marshall , Klein Ashwil
Published: December 2024

Malaria remains a life-threatening disease, particularly in Sub-Saharan Africa, with the emergence of Plasmodium-resistant parasites necessitating new chemotherapeutic drugs. This study evaluated the anti-plasmodial potential of phyto-mediated MgO@ZrO2 nanocomposites in Plasmodium berghei-infected mice. Green-synthesized nanomaterials were characterized using various analytical techniques. In the suppressive test, 25 mice were infected with 0.2 mL of blood containing ~ 1x10⁷ parasites and treated with 50, 100, and 200 mg/kg bwt of nanoparticles for 4 days. In the curative test, 25 infected mice were divided into 5 groups: groups I-III received 50, 100, and 200 mg/kg bwt nanoparticles; group IV received 1.4 mg/kg bwt artemether/lumefantrine; group V received saline. Bodyweight, packed cell volume, and survival time were monitored. Scanning and transmission microscopy revealed agglomerated spherical nanoparticles (42.71 ± 11.60, 60.22 ± 6.54, and 39.25 ± 9.80 nm). XRD showed MgO-NPs, ZrO2-NPs, and MgO/ZrO2-NPs with varied lattice patterns. Acute toxicity tests showed LD50 > 2000 mg/kg bwt. The nanoparticles suppressed parasites dose-dependently, with MgO-NPs, ZrO2-NPs, and MgO/ZrO2-NPs achieving 66.79%, 34.72%, and 41.02% suppression, respectively, at 200 mg/kg bwt. In the curative test, MgO-NPs > MgO/ZrO2-NPs > ZrO2-NPs showed significant inhibition (p < 0.05) compared to controls. These nanomaterials may serve as leads for antimalarial drug development.
Das Wagnis der Analyse
Authors: Croce Camilla
Published: December 2024

Der Beitrag thematisiert das Risiko der Analyse dabei sich einleitende auf das Lob des Risikos von Anne Dufourmantelle beziehend, in dem die Psychoanalytikerin schon vor einigen Zeit den Verlust in unserer gegenwärtigen Gesellschaft eine dem Leben nützliche und günstige Bedeutung des Risikos thematisierte. Das Wagnis betrifft die Analyse strukturell in ihren Akten und das schon ab dem ersten psychoanalytischen Akt des Übergangs von der Aufgabe der Analysantin zur Position der Analytikerin. In diesem Beitrag wird versucht die Struktur dieses Aktes zu veranschaulichen, dabei sich auf Lacans Vergleich im Seminar XV zwischen dem revolutionären und dem psychoanalytischen Akt stützend und den Akzent auf die Analyse als eine Reaktivierung der singulären Zeitlichkeit der Wiedergeburt zum Leben legt.
Physicochemical and bacteriological study of an urban stream in Bida north-central Nigeria
Authors: Obi Pauline Uchenna , Okeke Susan Kingsley , Achilike Blessing Amarachi , Adiele Nneoma Susan , Eze Simeon Uchechukwu , Umar Muazu , Mohammed Yakubu Manbe
Published: December 2024

Freshwater pollution by human activities is becoming a matter of urgent concern as it threatened it productivities and sustainability. This study was carried out to assess the physicochemical and bacteriological study of Water from Chikke Stream, Bida, Niger State, Nigeria. Samples were collected using standard method and procedure. The result showed all the measured physiochemical parameter differs significantly (p<0.05) among the sampled station except water temperature and pH which does not show significant difference (p>0.05) among sampling stations. A total of four (4) bacteria species were isolated with three-gram negative species namely; Klebsiella sp., Escherichia coli and Shigella sp. While Staphylococcus aureus is the only gram-positive species. Station 2 and 3 recorded the presence of four bacteria species while station 1 recorded the presence of three bacteria species. The presence of these species of bacteria in the stream is indication of poor water quality as a result of incessant anthropogenic factors such as agricultural activities and faecal contamination around the water body. Overall, there is need to minimize anthropogenic activities in or around water bodies for effective utilization of this unique resources
JALONS POUR LA RESTAURATION DE LA FAMILLE AUJOURDHUI
Authors: Koutchoro Allelua Magloire Okry
Published: December 2024

The various crises, violence and disaffection experienced by the family today highlight the need for informed reflection with a view to its restoration. It is a question of provoking a synergy of the various actors in social life to restore the family. For the family is both upstream and downstream of all the dynamics of society, to the point where it would never be abusive to assert that society is worth what the family is worth. The fundamental question in this research has been to determine how to restore the family to its splendour and its full vocation as the foundation of hope for every human being. The main objective is to identify the milestones that will enable the family to be restored in such a way as to bring out its primary meaning as a primordial fact in all human existence. On the basis of documentary research and qualitative data, we have studied the various elements of family life. The results revealed that education is the determining factor in reclaiming and restoring the family. Education in values and a good preparation for marriage are a constitutive guarantee promising a radiant future for the family. A sense of communication and a willingness to forgive one another are the glue that binds family members together.
COMBATTING CERVICAL DYSTOCIA: A RARE CASE REPORT
Authors:   Junior Resident- 3rd Year Obstetrics and Gynaecology Himalayan Institute of Medical Sciences Jolly Grant, Dehradun., Dhawan Simran , Agarwal Anchal ,   Assistant Professor, Obstetrics and Gynaecology Himalayan Institute of Medical Sciences Jolly Grant, Dehradun., Nautiyal Ruchira ,   Professor and Head, Obstetrics and Gynaecology Himalayan Institute of Medical Sciences Jolly Grant, Dehradun., Chauhan Nidhi ,   Professor Obstetrics and Gynaecology Himalayan Institute of Medical Sciences Jolly Grant, Dehradun.
Published: December 2024

Cervical dystocia refers to a difficult or abnormal labor condition in which the cervix fails to dilate adequately or at the normal pace during childbirth. This condition can lead to prolonged labor and may be associated with fetal distress, maternal complications, and an increased risk of cesarean delivery. Cervical dystocia can arise due to various factors such as maternal pelvic anomalies, excessive uterine muscle tone, malposition of the fetus, or previous cervical injury. Clinical assessment and careful monitoring of labor progress are crucial for identifying cervical dystocia early. Management typically involves medical interventions such as oxytocin administration to enhance contractions, manual dilation, or operative delivery when necessary. In some cases, cesarean section may be required for the safety of both mother and child. Early identification and timely intervention are vital to minimizing complications associated with cervical dystocia, ensuring better maternal and neonatal outcomes. This condition emphasizes the need for individualized obstetric care based on the specific factors contributing to the dystocia.
Online marketing campaigns’ aesthetics: Measuring the direct effect on customers’ decision-making
Authors: AlSokkar Abdullah , Ahmad Al-Gasawneh Jassim , Otair Mohammed , Alghizzawi Mahmoud , Alarabiat Deemah , Al Eisawi Dalia
Published: December 2024

This research aims to investigate the direct and formal effect of visual aesthetics on customers’ willingness to participate in an online marketing campaign, given that visual aesthetics is considered a salient design characteristic that customers tend to refer to when expressing their experience with the online retailer environment. This research study incorporates the Theory of Reasoned Action (TRA) and the Technology Acceptance Model (TAM) to propose and estimate this direct effect through structural aesthetics TAM model. In order to validate the proposed model, an online survey with interactive experience was constructed utilizing an open-source platform and was primarily sent to scholars specializing in HCI, informatics, user experience, and digital marketing research in the United Kingdom. The data were obtained from 360 participants, and Partial Least Squares (PLS) path modeling using SmartPLS 4 was employed to evaluate the proposed model. The empirical evaluation demonstrated and confirmed the authenticity and novelty of significant direct and formal effects of customers’ perceived visual aesthetics on their willingness to participate in an online marketing campaign (β = 0.462, t = 10.847, p < 0.001), and their usage attitude (β = 0.789, t = 39.622, p < 0.001). These findings highlight the importance of visual aesthetics in online marketing campaign design, suggesting that concise, well-organized, and visually appealing user interfaces is more likely to engage customers than a complex, cluttered one.
El derecho a la libertad personal en Colombia: un análisis de la procedencia del Habeas Corpus Correctivo en condiciones de violaciones masivas a derechos fundamentales
Authors: Mira González Clara María , Vélez Baena María José , Córdoba Ochoa Mariana
Published: December 2024

El presente artículo analiza las características del Habeas Corpus correctivo dentro de la declaratoria del Estado de Cosas Inconstitucional – en adelante ECI – presentado a partir de la Sentencia T 153 de 1998 en Colombia y propone, para la superación del mismo, la implementación de este recurso como un mecanismo que permite tanto la excarcelación como la concesión de subrogados penales ante las violaciones masivas de derechos fundamentales de personas detenidas y condenadas en Colombia. Lo anterior, con la finalidad de proponer algunas conclusiones críticas relacionadas con las privaciones de la libertad en situaciones de violación masiva de derechos humanos, la mayoría de ellas, producto de las condiciones actuales de nuestro actual sistema carcelario.
El énfasis de este trabajo será entonces el del análisis del Habeas Corpus como mecanismo correctivo de la privación de la libertad, realizando algunas comparaciones breves con la forma en la que funciona este recurso en países como España y Estados Unidos. El Habeas Corpus debes ser entendido como un derecho fundamental que funciona tanto para reparar las capturas ilegales como para prevenirlas y corregir las condiciones inhumanas de privación de la libertad. Este último sentido, el de corrección, es quizás el más preocupante, en las condiciones en las que se concede, en relación con la situación carcelaria actual.
Uma reflexão sobre os conceitos de campo e modos de existência de Pierre Bourdieu e Bruno Latour
Authors: Batista Cicera , Oliveira Valtenci Lima de Oliveira
Published: December 2024

Esta proposta pretende analisar possíveis conexões entre os conceitos de Pierre Bourdieu e os Modos de Existências de Bruno Latour, bem como problematizar as oposições entre os modos de pensar as relações de poder na sociedade. Adota-se para tanto, a pesquisa bibliográfica cuja perspectiva metodológica permite examinar os aportes teóricos a partir dos quais estes autores formulam os conceitos em questão, no esforço de refletir sobre a inter-relação dos sujeitos com seu entorno. A bibliografia permitirá analisar a ótica que estes teóricos consideram, e cujas tendências se diferem, mas que abordam aspectos em comum passíveis de análises críticas a partir das quais pode-se abrir novas perspectivas.
Mulheres e o cuidado no Sistema Único de Assistência Social
Authors: Aparecida da Silva Vanda , Moura Bueno Karina
Published: December 2024

Este artigo aborda o cuidado pelo seu viés coletivo enquanto proteção social e sua repercussão dentro e fora dos serviços do Sistema Único de Assistência Social (SUAS). O enfoque está nas personagens protagonistas do ato de cuidar: as mulheres, sejam as usuárias dos serviços sociais, ou as trabalhadoras do sistema. Por meio de uma revisão bibliográfica, o texto analisa pesquisas que enfatizam a construção da família e do papel feminino dentro dos serviços. Os resultados encontrados demonstram que os serviços da Assistência Social não conseguem romper com a lógica conservadora, sedimentada em ações que não alcançam a complexidade do cotidiano, sustentando posições acríticas diante do conceito de família, reforçando a heteronormatividade compulsória e os papéis de gênero naturalizados.
Burocracia e custo de transação econômica: um estudo de caso nos projetos de extensão da universidade federal rural do semi-árido (ufersa)
Authors:   , Oliveira Oskarine da Chagas
Published: December 2024

Esta pesquisa tem como objetivo identificar o efeito da burocracia no custo de transação econômica nos projetos de extensão, com financiamento externo, da Universidade Federal Rural do Semi-Árido (UFERSA). Nessa perspectiva, utilizou-se o método qualitativo, bem como o plano de enquete exploratório e descritivo. Para o desenvolvimento deste trabalho, aplicou-se o estudo de caso na UFERSA, no qual empregou a triangulação dos dados mediante observação, entrevista e análise documental. Nesse ínterim, foram realizadas entrevistas semiestruturadas com os responsáveis pela tramitação, celebração e execução dos projetos de extensão com financiamento externo. Os participantes envolvidos nesta pesquisa são: Divisão de Projetos (DDP) da Pró-Reitoria de Extensão e Cultura (PROEC), Divisão de Convênios (DICONV) da Pró-Reitoria de Planejamento (PROPLAN), Fundação Guimarães Duque (FGD), que atua como apoio técnico operacional na execução de projetos e três coordenadores de projetos de extensão. Os dados foram tratados, com vistas a atender aos preceitos da análise de conteúdo; para isso, primeiramente, foram transcritas as entrevistas que, posteriormente, foram importadas para o software Atlas ti 8.4. Logo, foi realizado o trabalho de codificação que, com a finalização, empregou-se a categorização dos dados, com o propósito de criar famílias, de acordo com as dimensões estudadas. Em seguida, foi possível conceber redes, para a devida análise e discussões. Os resultados evidenciaram que as normas e regulamentos, as quais regimentam a relação dos sujeitos da pesquisa, atenuam os efeitos da racionalidade limitada, da incerteza e do oportunismo. No entanto, identificou-se que o uso excessivo das normas e regulamentos ocasionam as disfunções da burocracia e acarretam custos de transação entre os agentes. Portanto, a contribuição desta pesquisa corresponde à evidenciação de que o exagero do uso da burocracia, ou seja, a sua disfunção, provoca implicações na relação entre os agentes, atuantes na tramitação dos projetos de extensão, acentuando o aumento dos custos de transação econômica.
Ensino, pesquisa, extensão: um estudo de caso na universidade federal rural do semi-árido, no estado do rio grande do norte
Authors:   , Santos Érica dos
Published: December 2024

O ensino, a pesquisa e a extensão são os pilares de sustentação de uma universidade. Eles têm a garantia constitucional de serem inseparáveis e nenhum deles deve estar sobreposto ao outro em relação ao trato e relevância. Esta pesquisa teve como objetivo analisar o cenário universitário quanto à participação docente em cada um desses pilares na Universidade Federal Rural do Semi-Árido. Para isso, propôs-se a identificar o quantitativo de docentes executando atividades nos pilares ensino, pesquisa e extensão, para assim esboçar um panorama demonstrando a distribuição dos professores nos pilares universitários; comparar a distribuição dos docentes, no tripé universitário (ensino, a pesquisa e a extensão) por campus da IFES; e verificar as perspectivas dos gestores de cada pilar universitário, acerca da participação docente no tripé universitário. Quanto à metodologia, a pesquisa apresenta natureza qualitativa, exploratória descritiva, realizada por meio de estudo de caso com abordagem de triangulação de dados através de observação, análise documental e entrevista semiestruturada, aplicada com os sete principais gestores institucionais responsáveis pela tomada de decisão quanto ao tripé universitário. Os dados referentes à distribuição docente foram tratados por meio do software Microsoft Excel® e os dados oriundos das entrevistas foram tratados por meio de análise de conteúdo. Neste, as entrevistas foram transcritas e inseridas no software Atlas ti 8.4. Em seguida, foi realizada a codificação de informações de acordo com a abordagem desta pesquisa para serem criadas as redes e finalizado com as análises e discussões. Os resultados mostram que a distribuição docente nos três pilares universitários é desproporcional: tanto a nível geral, quanto por campus, verificou-se que o pilar ensino tem o maior quantitativo de docentes, seguidos pelo pilar pesquisa e extensão. Em relação à perspectiva dos gestores acerca da participação docente, eles consideraram que o quantitativo de professores que se dedicam somente ao ensino é alto; satisfatório quando se trata de docentes envolvidos em atividades de pesquisa; e baixo quando se referem a professores dedicados às atividades de extensão. Os gestores apresentaram as dificuldades existentes no cenário atual e, mesmo diante delas, os entrevistados acreditam que essa realidade pode melhorar, ou seja, a pesquisa e a extensão podem ter uma maior adesão de docentes desde que haja investimentos internos e externos.
DESENVOLVIMENTO DE UMA METODOLOGIA DE ENSINO BASEADA NO DESIGN PARA A INOVAÇÃO SOCIAL E SUSTENTABILIDADE
Authors: Maurell Laís , Cipolla Carla
Published: December 2024

Este artigo apresenta o desenvolvimento de uma metodologia de ensino que tem como finalidade promover para alunos do ensino médio o conhecimento e a prática da inovação social para a sustentabilidade, podendo também ser adaptada a outros níveis de ensino. A DESISME (Design para a Inovação Social e Sustentabilidade Metodologia de Ensino) foi desenvolvida mediante uma combinação da design science research (DSR) com a pesquisa-ação, em um processo de cinco ciclos aplicados em sala de aula por uma das autoras, que é professora de Física no ensino médio de uma escola pública do Rio de Janeiro, utilizando um plano de aulas relativo aos temas de geração de energia e poluição ambiental. A DESISME possui dez etapas e utiliza o design como modelo de organização dos métodos de ensino compreendidos por ela. Com base no teste da metodologia aplicado, conclui-se que a DESISME, que está inserida na Educação para o Desenvolvimento Sustentável (EDS) e na Educação para Inovação Social (SIE), possui potencial para desenvolver nos alunos competências que são pretendidas nessas duas novas formas de educação.
Antiepileptic Impact of Isoindole-1,3-diones Compounds: An Updated Review on Diversified Synthesis and Modes of Action
Authors: Kurmi Rajan Kumar , Sinha Reema , Agrawal Anurag , Bansal Sandeep Kumar , Lavhale Pallavi M , Srivastava Snigdha
Published: December 2024

Epilepsy is a growing concern for the scientific community globally as less than 80%
of individuals experience reduced seizure severity with existing antiepileptic medications and the
chances of relapses are very high with those medications. Therefore, the existing problem requires
more attention to unravel the chances of relapses and adverse effects of available
medications. Isoindole-1,3-diones serve as a valuable scaffold with diverse biological activities,
including analgesic, anti-inflammatory, and hypolipidemic properties. This review will emphasize
the antiepileptic behaviours of the Isoindole-1,3-diones with diversified synthetic procedures and
modes of action. For this purpose, an extensive literature survey was undertaken through different
online platforms such as PubMed, Web of Science, Scopus, SciFinder, Google Scholar, Science
Direct, etc. Some N-substituted Isoindole-1,3-diones have demonstrated promising anticonvulsant
activity, primarily by effectively blocking sodium channels. Epilepsy is often linked to channelopathies
involving α, and β-subunits, and medications have specific mechanisms for binding
with the α-subunit of the sodium channel. Analyzing the structural features of phenytoin, carbamazepine,
and lamotrigine revealed that benzene or phenol substitution, along with the addition of a
chloro group, enhances their activity in the maximal electroshock seizure (MES) and subcutaneous
pentylenetetrazol (scPTZ) tests. This review focuses on the role of specific sodium channels
in electrical signalling and neurological conditions, emphasizing the significance of Isoindole-
1,3-diones and their derivatives in designing potent anticonvulsant agents, particularly in the development
of selective sodium channel inhibitors.
Bio-based Polymers and Microcarriers Improve Stability and Efficacy of Essential Oils
Authors: Ghosh Sourav , Dutta Srabona , Basu Biswajit , Prajapati Bhupendra G.
Published: December 2024

Current developments provide an overview of alginate electrospinning for biopolymers
in pharmaceutical and biological applications, but their volatile nature and susceptibility to degradation
pose challenges to their storage and use. Due to their innate medicinal qualities, pure
essential oils have drawn a lot of attention to their many uses, such as aromatherapy and medicine.
However, the stability, regulated release, and sustained efficacy of EOs are complicated by
their brittleness and sensitivity. Bio-based small carriers as well as polymers have recently come
to light as a viable solution to these problems. To improve the stability and therapeutic efficacy of
essential oils, this review study investigates the novel use of bio-based microcarriers and polymers.
By encapsulating essential oils within biocompatible materials, such as microcarriers and
polymers derived from natural sources, researchers have been able to extend their shelf life, improve
their controlled release, and enhance their bioavailability. The general stability, as well as
bioavailability of these encapsulated EOs, are improved by the interaction of the natural qualities
of essential oils with the specific properties of bio-based polymers. This paper examines the design
and manufacturing concepts of bio-based microcarriers, emphasizing encapsulating techniques
and the variables affecting release kinetics. Additionally, it highlights the potential uses of
EO-loaded tiny carriers in various fields, such as cosmetics, agriculture, and medicine. This paper
also delves into recent advancements in this field, discussing the fabrication techniques, characterization
methods, and application areas of bio-based microcarriers and polymers for essential oil
delivery.
Tracking Road Safety Efficiency Gains Over Time Within the Gulf Cooperation Council Region
Authors: Alfaki Ibrahim Abdalla
Published: December 2024

Objective

This study evaluates and tracks the progress of road safety performance in six high-income Gulf Cooperation Council (GCC) countries from 2010 to 2019, using a Data Envelopment Analysis (DEA)-based Malmquist Productivity Index (MPI). It employs both the constant and variable return-to-scale perspectives.

Methods

Using the DEA-based Malmquist framework, this study creates a composite index for GCC countries and benchmarks their road safety efficiency, which few previous studies have comprehensively examined. The study measured road safety performance using various input and output variables, including the number of vehicles, population, road quality, implementation of road safety practices, road crash fatality rates, and economic burden due to road injuries.

Results

Over the ten-year period, the findings reveal significant disparities in fatal crash risk and road safety progress among GCC countries. While some countries have shown improvements in efficiency and technology, others have experienced stagnation or regression. Top-performing countries have primarily improved road safety through technological advancements.

Conclusion

GCC countries have significant potential to reduce road crash outcomes and enhance overall road safety. Policymakers can leverage the insights from this research to identify key areas for improvement, guide targeted interventions, allocate resources more efficiently, and formulate comprehensive policies for impactful and sustainable road safety strategies.
Mapping the Intellectual Structure of Internet of Vehicles Research: A Bibliometric Analysis of Emerging Technologies and Applications
Authors: Sugandh Urvashi , Panwar Arvind , Gaba Priyanka , Kumar Manish
Published: December 2024

The Internet of Vehicles (IoV) is an emerging field that has attracted a lot of attention from researchers and practitioners alike. It encompasses a range of technologies and applications that enable communication and data exchange between vehicles, infrastructure, and other connected devices. As the IoV continues to evolve, it is important to understand the intellectual structure of the research that underpins this field. In this paper, we conduct a bibliometric analysis of IoV research to map its intellectual structure and identify emerging technologies and applications. We conducted a systematic review of the literature using bibliometric analysis techniques, including co-citation analysis and network visualization. We analyzed the publication and citation patterns of IoV research, identified the most influential authors, journals, and institutions, and explored the intellectual structure of the field using network analysis techniques. Our results show that IoV research has grown rapidly over the past decade, with a significant increase in publications and citations in recent years. The study also identified several emerging technologies and applications in IoV research, including connected vehicles, vehicular networks, autonomous driving, and smart transportation systems. These emerging technologies and applications have the potential to transform the transportation industry and improve road safety, traffic management, and energy efficiency.