bluuebunny/crossref_metadata_2025 huggingface dataset:
DRUG REPURPOSING: IDENTIFICATION OF POTENTIAL DRUG TARGETS AGAINST NONSTRUCTURAL PROTEIN 1 (NSP-1) OF SARS-COV-2 THROUGH MOLECULAR DOCKING AND MOLECULAR DYNAMIC SIMULATION USING FDA APPROVED DRUGS
Authors: Mateen Rana Muhammad , Saqib Muhammad Arif Nadeem , Hussain Mureed , Fareed Muhammad Irfan , Afzaal Muhammad Sohail , Parveen Rukhsana
Published: March 2023

Since its pandemic in 2019, SARS-CoV-2 has badly affected the countries around the globe. There is no FDA approved drug for the treatment of the disease. In this study, we evaluated potential targets against non-structural protein-1 (Nsp-1), which is crucial in disturbing host-translational machinery. As the completecrystal structure of the Nsp-1 was not available, we used I-TASSER for making the complete structure of the protein. The structure was verified using ERRATand PROVEAN. As the previous studies had reported different binding sites for this protein, we used blind docking of Nsp-1 with 2225 FDA approved drugsusing AutoDock Vina. Based upon the residue interactions obtained from the blind docking, we selected C-terminal of Nsp-1 for specific docking against FDAapproved drugs. Based upon the docking results, Glycyrrhizin was found to be suitable drug showing strong interactions. We further verified the glycyrrhizin-Nsp-1 complex by analyzing the trajectory for 60 ns, by comparing with individual protein. RMSD analysis during the trajectory and RMSF analysis alsosuggested the stability of the protein-ligand complex and resulted in 49 hydrogen bonds during the simulation process. The study suggests that Glycyrrhizin can act as potential inhibitors against Nsp-1 of SARS-COV-2.
Mhd Stagnation Point Flow and Heat Transfer of Cu –Water Nanofluid over A Stretching Sheet
Authors: Bashir Rafia , Ashraf Muhammad , Ali Kashif
Published: March 2023

A comprehensive study of Magnetohydrodynamics flow (stagnation Point) with heat transferal properties of Cu–Water nanofluid along a stretched sheet in the existence of a transverse magnetic field is analyzed. The governing equalities along with their conditions on boundary points are firstly converted to ordinary differential equations of non-linear category by similarity transformations. Lastly finite difference discretization is utilized. The flow and heat transfer parameters, namely: stretching parameter, magnetic parameter, the Prandtl number and solid volume fraction are investigated by tablular and graphical representation.
Study of Properties of Polyethylene Glycol and Its Glass Fibers Composites under UV-Rad for Oils Filtration Applications
Authors: Alesa Hanaa Jawad , Al – Dabbagh Balqees M.
Published: March 2023

This study determines the effects of UV radiation and heat treatment on many flow and mechanical parameters of PEG 4000, including flow time and viscosity (specific, reduced, relative, and intrinsic). Solubility time and shore D hardness are among the mechanical characteristics. By adjusting the concentrations of solutions in the range (0.01–0.03) g/ml of heating and non-heating PEG powders, and examining the polymer's solubility at the same time, the flow characteristics of the polymer are explored. Random glass fiber reinforcement in the range of 0.1–0.4 wt has also been studied to indicate the effect on shore hardness. After exposing the produced plates to ultraviolet light, the efficacy of the plates in purifying the oil from contaminants was investigated. The results show that increasing the concentration increases all types of viscosity and flow time, with the exception of intrinsic viscosity, which decreases as concentrations increase. Other parameters decrease after the first UV ray and heat treatment, but increase as the time of UV ray treatment increases. Furthermore, increasing the weight ratio of glass fibers from 0.1 to 0.4 wt lowered shore hardness, whereas increasing the weight ratio at the same previous range increased it after UV rad. While solubility data refers to increasing polymer weight and radiation help increase solubility time. The filtration efficacy   of the small particles of the produced filters increased after the overlapping plates were exposed to UV radiation, owing to the smaller pore diameters.
LALS PhD student seminar
Authors: students LALS PhD
Published: March 2023

Come along and hear about the innovative research being done by LALS PhD students. Each student will speak about a facet of their research for 3 minutes!
Cắt đoạn dạ dày cực dưới với miệng nối kiểu péan điều trị ung thư 1/3 dưới dạ dày ở người cao tuổi
Authors: Tiến Ngọc Đặng , Hồng Sơn Trịnh , Đăng Vững Nguyễn , Văn Tịnh Lê
Published: March 2023

Mục tiêu của nghiên cứu là mô tả đặc điểm lâm sàng, cận lâm sàng, giải phẫu bệnh và kết quả phẫu thuật cắt đoạn dạ dày cực dưới với miệng nối kiểu Péan điều trị ung thư biểu mô tuyến nguyên phát 1/3 dưới dạ dày ở người cao tuổi tại Bệnh viện Hữu nghị Việt Đức trong khoảng thời gian từ 1/2018 - 2/2020. Chúng tôi sử dụng nghiên cứu mô tả can thiệp lâm sàng, theo dõi dọc với 39 bệnh nhân ≥ 60 tuổi bị ung thư biểu mô tuyến nguyên phát 1/3 dưới dạ dày được phẫu thuật cắt đoạn dạ dày cực dưới với miệng nối kiểu Péan. Kết quả tỷ lệ 48,7% nữ và 51,3% nam, triệu chứng đau thượng vị chiếm 84,6%, CEA và CA19-9 cao ở 11,1%; CA72-4 cao ở 20%. Chụp cắt lớp vi tính ổ bụng 82,1% dày thành dạ dày. Giải phẫu bệnh vị trí hay gặp nhất là hang vi bờ cong nhỏ 46,5%, giai đoạn sớm chiếm 38,4% và giai đoạn tiến triển 61,6%. Thời gian mổ trung bình là 180 phút, không có tai biến trong mổ, không có tử vong hậu phẫu, tai biến và biến chứng sau mổ tỷ lệ thấp và nhẹ. Thời gian sống thêm đến thời điểm kết thúc nghiên cứu trung bình là 41 ± 8,9 tháng, tỷ lệ sống sót là 92,3%. Kết luận: miệng nối Billroth I kiểu Péan cho kết quả tốt trên bệnh nhân cao tuổi, phù hợp với sinh lý, rút ngắn thời gian phẫu thuật, giảm các biến chứng về nội khoa do gây mê kéo dài, nhanh chóng duy trì chức năng của đường tiêu hóa.
Antena doble Biquad con reflector parabólico para la banda de 2.4 GHz
Authors: Rivero Jiménez Daniel , Beltrán Casanova David , Cordoví Rodríguez Tuan
Published: March 2023

Las antenas con reflectores parabólicos se utilizan extensamente en sistemas de radiocomunicaciones a partir de los 800 MHz y los altos valores de ganancia que poseen las hacen muy populares en las bandas de microondas. El presente trabajo expone el diseño y la evaluación de una antena doble Biquad con reflector parabólico cilíndrico para operar en la banda de 2.4 GHz, con el objetivo de dar respuesta a la solicitud realizada por especialistas de la Empresa de Antenas de Villa Clara, en el marco del convenio de colaboración existente entre esta empresa y la Facultad de Ingeniería Eléctrica (FIE) de la Universidad Central “Marta Abreu” de Las Villas (UCLV); reflejo del vínculo universidad-empresas al que ha llamado la dirección del país. Por esta razón ha sido estudiada, diseñada y simulada, con el software CST Microwave Studio 2018 y la antena Biquad, evaluando el efecto que produce en los parámetros de la antena el empleo de reflectores. Los resultados obtenidos de las simulaciones fueron validados a partir de la construcción de prototipos en los talleres de la Empresa de Antenas de Villa Clara y la medición de los principales parámetros con el equipamiento disponible en la empresa alcanzando efectos satisfactorios en cuanto a los parámetros fundamentales que caracterizan a esta antena: pérdidas por retorno (-35 dB), Razón de Onda Estacionaria (1.03), ganancia (13.65 dB) y patrón de radiación. Se destacaron las antenas por su fidelidad en el trabajo en la banda wifi de 2.4 GHz, para la que fue diseñada.
The Role of Dialogue in the Teaching of Reading in South Africa
Authors: Steinke Kellie
Published: March 2023

The importance of classroom dialogue in promoting effective literacy skills is well documented. Despite comments in a recent paper that there is scant research on classroom observations around print in South Africa post-1994, there have in fact been several studies that have observed classroom practice around reading. The sum of these studies seems to indicate that teaching styles have changed very little over the past 30 years, and that meaningful classroom interaction between teacher and learner remains largely absent. This paper will focus on how the pedagogical content knowledge (PCK), of teachers affected their classroom interaction with Grade three and four learners in two semi-urban schools in the Midlands area of KwaZulu-Natal, South Africa. It forms part of a larger, 2019, mixed methods, multiple case study that involved eight teachers and their learners, and examined the effects of PCK on the teaching of reading in these Grades. Findings were that, despite some teachers using additional training, ultimately none were managing to move their learners from decoding to reading effectively, and that lack of meaningful interaction played a central role in this.
Narrating Tales of Displacement: Fragmented Memory and Partition Stories
Authors: Dr. Ishmeet Kaur Chaudhry
Published: March 2023

For the children of families that have experienced partition, relating to roots and a place of belonging is never without complications. They tend to relocate themselves multiple times in physical places as well as mental spaces. Unfortunately, the final settling never takes place for them, neither in the new place, where the family relocates to, nor in the mind that is a storehouse of experiences of migration. They remain ‘in-between’ and continue negotiating between the past and the present through fragmented as well as tormented memories. This paper attempts to study the complexity of belongingness for those who have lived the experiences of the Partition and how this complexity continues across generations. This will be done through a methodology of writing personal narrative and reviewing testimonies of those who experienced the Partition, along with the members of their families. The primary sources for this paper are personal testimonies of the family members, community magazine Pothohar, the short story ‘Bhenji Parmeshri’ based on the oral tales narrated by the researcher’s grandmother, films Sardar Mohammad (2017) and Eh Janam Tumahare Lekhe (2015) and a testimony of Mohinder Kaur in the newspaper. The paper will evaluate the experience of those who suffered owing to Partition by connecting the contact points, like experience of migration, displacement of families, killing of daughters by their fathers etc. as depicted in the texts and testimonies taken for the study.  Personally, the researcher’s grandfather, Harbans Singh lived for 102 years witnessing and participating in events around the Freedom Movement, the Partition of India, the 1971 war with Pakistan, the Emergency, the 1984 anti-Sikh massacres, and finally the recent pandemic (COVI-19). At all major incidences he suffered personal losses. While throughout his life, he kept narrating his experiences of the Partition and the eventual victims’ migration to India, but towards the end of his life, he refused to talk about it anymore. He became very selective in his choice of subject for a conversation. Nevertheless, his village and place of birth, never skipped him. Even in his dementia, any reference to his birthplace would attract his attention. The paper is an attempt to study how physical places become permanent fixatures and sites of memory that surface at a slightest trigger. These incidences are the deepest traumatic sites that never recover.
Prognostic variables and decannulation of tracheostomy in the long term acute care environment: A case for clinician driven decision making
Authors: Weil Kimberly , Baumann Vanessa , Brown Brittany , Nadeau Rebecca , Gerstenhaber Brett , Manning Edward
Published: March 2023

Purpose Tracheostomy is a necessary procedure required for prolonged mechanical ventilation in long-term acute care hospitals (LTACH). Many factors influence successful decannulation, or tracheostomy removal, and it is unclear what factors are essential for determining decannulation. The purpose of this study was to determine retrospective performance of single prognostic variables for successful decannulation, like peak expiratory flow measurement, overnight oximetry testing, and blood gas analysis. Methods A retrospective analysis of a three-year period to investigate the association between peak flow (PF) measurements ≥160 L/min, successful overnight oximetry (ONO), sex, and decannulation success. Average PF measurements, arterial blood gas (ABG), days on mechanical ventilation, LTACH length of stay (LOS), and age were also investigated. Results We examined the records of 135 patients, 127 of which were successfully decannulated. PF measurements ≥160 L/min (P 0.16), sex (P <0.05) and passing ONO (P <0.05) were significantly different between successfully and unsuccessfully decannulated patients; mean ABG (PH, PaCO2, PaO2), mechanical ventilation days, LOS, and age were not significantly different (P >0.05). Conclusions These results suggest no single prognostic variable can predict decannulation outcomes. Rather, clinical judgment of experienced medical professionals appears sufficient to achieve a 94% decannulation success rate. Additional investigation is required to determine what metrics are necessary, or if clinical judgment alone can predict decannulation success. Key Words: Tracheostomy decannulation, long-term acute care facility, peak expiratory flow measurement
Türkiye'de Dini Otorite Meselesi ve Dini Bilginin Bireyselleşmesi
Authors: GÜMÜŞAY İbrahim
Published: March 2023

Bu çalışmada Türkiye'de dini otorite meselesi ve modernleşmeye bağlı olarak dini otoriteye meşruiyet sağlayan dini bilginin bireyselleşmesinden bahsedilmektedir. Otorite kavramıyla bağlantılı olarak dini otorite "dinin temel esasları noktasında inananlar üzerinde belirleyici bir hüküm verme yetkisi" şeklinde tanımlanmaktadır. Ehl-i Sünnet inancına göre İslam'da bu yetki Allah'a ve O'nun temsilcisi olan Hz. Muhammed'e aittir. Onun dışında kendilerini "Peygamber varisi" olarak gören, vahiy ve sünnetten hareketle "icma" ve "kıyas" yöntemleriyle dini bilgi üretme biçimini elinde bulunduran din otoritesi temsilcileri bulunmaktadır. Modernleşmenin bilgiye ve bireye yüklediği anlam, gelenekselliği aşamayan din otoritesi temsilcilerinin eleştirilmesini mümkün hale getirmektedir. Türkiye'de de bireyselleşen dindarların tutumlarında bu durum açık bir şekilde görünmektedir. Bilgiye modern dönemde kolay erişilmesi, din otoritesi temsilcilerinin "geleneksel" olarak nitelenen yorumlarının terk edilmesini ve bireyselleşen dindarların modernleşmenin sağladığı imkanlarla dini bilgiyi kendilerinin elde etmesini kolaylaştırmaktadır.
Design and Implementation of Low-Cost Data Acquisition System for Small and Medium Enterprises (SMEs) of Pakistan
Authors: Muhammad Imran Majid  , Ejaz Malik  , Tahniyat Aslam  , Osama Mahfooz  , Fatima Maqbool
Published: March 2023

This paper presents the development of low-cost and robust industrial IoT based data acquisition system primarily focused on domestic manufacturing industries striving to achieve goals and benefits of “Industrial 4.0”. This proposes aims to promote DAQ System integration in traditional manufacturing process of the small and mid-sized industries of Pakistan with limited capacity of investment. Proposed method comprises of Arduino and it’s IoT features for Data Collection, along with a self-developed PC based Centralized Software for Collection of Data, Graphical User Display and Storing collected Data in Local SQL Database. PC based Software replaces requirement of multiple software in case of traditional low-cost DAQ systems, like OPC Software for collecting data from industrial hardware, Java or PHP based any GUI and SQL Data storage. The analysis of work is done with the help of the Message Queue Telemetry Transport (MQTT) protocol. This project will be in further stages evaluated to add features of Supervisory Control, along with Data Acquisition hardware with minimum increase in cost and further upgrading PC Software to add more features of Industry 4.0, as compared to costly commercial solutions available in the market. A machine learning algorithm, k-nearest neighbors algorithm has been used to classify sensitive and non-sensitive data for improvising cloud security. K-Nearest Neighbors is also called KNN algorithm which is supervised machine learning classifier.
Analysis of Stochastic Patterns of Daily Minimum Extreme Temperature of Karachi in Global Climate Change Perspective
Authors: Muhammad Atif Idrees  , Syed Ahmed Hassan  , Muhammad Arif Hussain
Published: March 2023

Effects of climate change are a critical and globally accepted phenomenon and gradually becoming inevitable and catching the attention of policymakers around the world. Temperature is a principal climatic factor and is defined as the degree or intensity of heat causing huge consequences on human beings’ lives. This paper suggests some stochastic approaches to do an analysis of the Karachi region’s daily minimum extreme temperature from Jan 1, 2010, to Dec 31, 2014. It is observed that the average daily minimum temperature fits the Markov chain and its limiting probability has reached steady-state conditions after 20 to 87 steps or transitions. The results indicate that after 20 to 87 days the distribution becomes stationary. The smaller steady-state time represents the stationary of the data series, whereas long-term behavior shows non-stationarity in trend behavior in the respective seasonal time series. Furthermore, the overall annual dormancy of 24 o C to 31o C daily minimum temperature was analyzed early part of the summer season. This study can be useful for weather variability forecasting.
STRATEGI PEMASARAN PRODUK KERAJINAN MANIK-MANIK DI KELURAHAN SIPIROK GODANG KECAMATAN SIPIROK KABUPATEN TAPANULI SELATAN
Authors: Azmi Nurul Widya Fuji Astuti  , Nurul Izzah  , Muhammad Isa
Published: March 2023

Kerajinan manik-manik menjadi salah satu produk unggulan dari Kecamatan Sipirok Kabupaten Tapanuli Selatan. Pemasaran pada produk kerajinan manik-manik masih disekitar Kecamatan Sipirok saja dengan sistem pemasaran yang masih sederhana dan tradisional. Penelitian ini bertujuan untuk mengetahui strategi pemasaran produk kerajinan manik-manik di Kelurahan Sipirok Godang Kecamatan Sipirok Kabupaten Tapanuli Selatan. Penelitian ini merupakan penelitian kualitatif, subyek dari penelitian ini ialah bagian pembuatan dan pemasaran produk kerajinan manik-manik dengan pengambilan sampel sumber data dilakukan secara snowboal dan purposive. Teknik pengumpulan data diperoleh dari hasil observasi, wawancara, dokumentasi dan studi kepustakaan. Teknik analisis data nya meliputi reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa strategi pemasaran pada produk kerajinan manik-manik dapat ditempuh dengan analisis matriks SWOT yang terdiri dari strategi S-O yaitu meningkatkan permintaan pasar, meningkatkan inovasi dan kreatifitas produk, menyesuaikan harga dengan produk yang diproduksi, meningkatkan kualitas produk dan membuat promosi yang menarik. Strategi W-O yaitu menambah jaringan pemasaran, mengoptimalkan bagian pemasaran, mencari bahan pengganti dan mengadakan pelatihan. Strategi S-T yaitu terus melakukan inovasi dan meningkatkan kualitas produk, memperluas jaringan pemasaran, promosi dengan memanfaatkan internet. Strategi W-T yaitu cepat dan tanggap apabila terjadi kendala, terus meningkatkan hubungan internal dan eksternal usaha produk kerajinan manik-manik agar mengungguli persaingan dengan produk sejenis.
PENGARUH IMPLEMENTASI ETIKA BISNIS, KONSEP PRODUKSI DAN DISTRIBUSI PADA UMKM TERHADAP PROFITABILITAS DALAM PERSPEKTIF EKONOMI ISLAM
Authors: Siti Amelia  , Muhammad Iqbal Fasa  , Suharto
Published: March 2023

Penelitian ini bertujuan untuk mengetahui bagaimana implementasi etika bisnis islam, konsep produksi, dan distribusi bagi usaha mikro kecil dan menengah (UMKM) untuk menghasilkan profitabilitas. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana konsep Islam etika bisnis, konsep produksi, dan distribusi pemrosesan. Lalu bagaimana implementasinya untuk usaha mikro kecil dan menengah (UMKM) dimana hasil penelitian ini dapat digunakan sebagai resume dari model untuk usaha mikro kecil dan menengah (UMKM) lainnya tentang etika bisnis Islam, konsep produksi, dan distribusi yang baik bagi profitabilitas. Penelitian ini dilakukan dengan metode penelitian deskriptif kualitatif yang menggunakan studi kepustakaan dan resume hasil penelitian sebelumnya. Hasil penelitian menunjukkan bahwa dengan menerapkan etika bisnis islam dalam proses produksi dan distribusi maka akan menghasilkan profitabilitas yang baik bagi usaha mikro kelas dan menengah (UMKM). Para pelaku usaha mikro kecil menengah (UMKM) telah memahami standar prinsip-prinsip etika bisnis syariah dan melalui penelitian ini juga dapat diketahui bahwa usaha mikro kecil dan menengah (UMKM) yang dipelajari telah memenuhi standar konsep produksi dan distribusi dalam Islam dan menghasilkan profitabilitas dengan baik.
ANALISIS TANTANGAN PENERAPAN PAJAK KARBON DI INDONESIA
Authors: Hilwa Nurkamila Maghfirani  , Namira Hanum  , Roidah Dzata Amani
Published: March 2023

Kebijakan pajak karbon sebagai pigouvian tax merupakan salah satu upaya pemerintah Indonesia untuk mengatasi eksternalitas negatif yang ditimbulkan atas emisi karbon.  Indonesia akan mulai menerapkan kebijakan pajak karbon secara terbatas pada tahun 2022 pada sektor Pembangkit Listrik Tenaga Uap (PLTU) Batubara. Penerapan kebijakan pajak karbon masih harus memperhatikan beberapa hal yang dapat disebabkan atas pengimplementasian kebijakan tersebut. Oleh karena itu, penelitian ini bertujuan untuk menggambarkan tantangan yang akan dihadapi Indonesia dalam penerapan pajak karbon mendatang. Penulis menggunakan jenis penelitian kajian literatur dengan teknik analisis data kualitatif deskriptif dan sumber data diperoleh melalui data sekunder. Penelitian ini menggunakan pendekatan kualitatif dengan jenis penelitian deskriptif, dan sumber data diperoleh melalui data sekunder. Penulis menemukan bahwa tantangan yang akan dihadapi Indonesia seperti timbulnya distorsi ekonomi dan dampak pada rumah tangga berpendapatan rendah.
FAKTOR-FAKTOR YANG MEMPENGARUHI PENINGKATAN DAN PENURUN PDRB SUMATERA UTARA
Authors: Tyana  , Andrew  , Winson  , Frentyo  , Devin
Published: March 2023

Economic development can be carried out if an area experiences an increase in economic growth. Therefore, a study was conducted to find the factors that influence the decline and increase in PDRB in North Sumatra algo gives recommendations to increase the regional income. PDRB data from 2015 to 2020 is presented above constant prices to find out the rate of PDRB growth over time. The results of the data analyzed show that the factors that influence the increase and decrease in GDP are investment, consumption, government spending, and export and import. In 2022, the North Sumatra Government can focus on lowering and lowering the first level first. Then it can carry out equitable development by improving service infrastructure, improving digital infrastructure, improving the economy in the tourism and MSME sectors and optimizing productivity in order to achieve increased income.
PERKEMBANGAN SISTEM INFORMASI MANAJEMEN (SIM) DI INDONESIA
Authors: Alfatul Hisabi  , Amelia Azura  , Dhita Lutfiah  , Nurbaiti
Published: March 2023

Management Information System (MIS) is a systematic network in the administration and handling of information that aims to create data that will be provided to each time as a reason for making choices to achieve organizational goals. The purpose of a management information system is to provide information used in calculating the cost of services, goods, and other necessities desired by executives; provide data used in compiling, controlling, assessing, and improving consistently; Provision of data for decision making of a company. The historical background of management information systems basically cannot be separated from the development of data technology. The development of Management Information Systems (MIS) has existed for a long time but is now more developed, especially in Indonesia. Management Information System (MIS) improvements have been recognized by the Big Screen Organization. early understand that the biggest obstacles come from the center to the upper management layers, and not from the bottom board. Implementation of Management Information Systems in Indonesia that regularly deals with the public includes: Management Information Systems in educational institutions, Management Information Systems in health institutions, Management Information Systems in banking institutions.
USAHA PENGEMBANGAN UMKM MELALUI E-COMMERCE
Authors: Nabiil Salasa Ramadan  , Niki Ayu Purwanti  , Siti Maysaroh  , Nurbaiti
Published: March 2023

Penelitian ini bertujuan untuk mengetahui seberapa jauh usaha dalam pengembangan UMKM yang dikembangkan lewat E-commerce dan Metode yang di pakai pada penelitian ini memakai  sistem atau pendaktan kepustakaan ( library research). Dalam menganalisis data, peneliti secara bertahap menggunakan reduksi data, penyajian data, dan verifikasi data. Selain itu dalam menganalisis kinerja guru-peneliti menggunakan prosedur pengindeksan data. Hasil penelitian ini menunjukkan bahwa pera E-Commerce sangat berpengaruh terhadap jalannya Usaha usaha kecil.  Usaha mikro kecil dan menengah yang disingkat UMKM ialah sumber kekuatan untuk perekonomian di Negara kita, UMKM memiliki kedudukan bagus di dalam perekonomian Negara Indonesia, karena UMKM dapat meningkatkan kemakmuran sejumlah pelaku usaha. Di dasari semangat para pelaku usaha UMKM dapat didirikan. Dengan kekuatan adanya internet kita bisa mengirimkan apa saja bentuk data, seperti gambar, suara, grafis, dan video. Dan berkembang pesatnya jaringan internet menjadi sarana yang baik untuk memulai jalan yang baru mempromosikan produk. Biaya yang dibutuhukan juga sangat terjangkau dan bisa mencakup luas.
ANALISIS BIBLIOMETRIKA PERAN BANK WAKAF MIKRO DALAM MENDORONG KESEJAHTERAAN UMKM DI INDONESIA
Authors: Ismail  , Andri Soemitra
Published: March 2023

Sistem ekonomi islam selalu berkontribusi besar dalam perkembangan ekonomi nasional dan sebagai alat pemecah kemiskinan, disamping itu dalam Al-Quran sudah jelas tertera larangan riba. Salah satu Lembaga keuangan mikro syariah yaitu Bank Wakaf Mikro hadir dengan konsep dengan segala kemudahan menggunakan prinsip-prinsip syariah. Penelitian ini merupakan studi literatur dengan menganalisis beberapa literature terpilih 5 tahun terakhir di google schoolar dengan menggunakan aplikasi Publish or perish. Hasil dari penelitian ini menunjukkan bahwa Bank Wakaf Mikro memainkan perannya sebagai lembaga yang non riba, memberikan pembiayaan tanpa agunan serta memberikan pendampingan untuk mendorong keberhasilan mencapai kesejahteraan UMKM di Indonesia serta membantu para nasabah UMKM terlepas dari jeratan Rentenir yang mengambil keuntungan semata.
KETAKUTAN, PERAN INVESTOR INSTITUSI DAN PERILAKU HERDING DALAM FASE PANDEMI COVID 19
Authors: Fenny Marietza  , Nikmah Nikmah , Fitrawati Ilyas  , Indah Oktari W
Published: March 2023

This study aims to examine the effect between fear of death caused by the covid 19 virus and institutional ownership on herding behavior in companies listed on the LQ45 index (JSII) in the period from 2019 to 2021. The fear variable with the GFI index is a variable that has never been used before by previous studies to be a variable that can estimate whether fear can affect herding behavior. The sample of this study is companies listed on the LQ45 Index on the IDX from 2019 to 2021. The analysis method used is multiple linear regression assisted by Eviews in data processing. The results showed that the fear associated with the global mortality index was able to influence the occurrence of herding behavior on the LQ45 index. Meanwhile, the role of institutional ownership in companies on the IDX is unable to influence the occurrence of herding behavior. This study also proved that at the end of the year and the beginning of 2020 (honeymoon phase) using rolling window regression. It is proved that there has been a herding behavior caused by the fear of investors.
Vinca (Catharanthus roseus) containing phytochemicals and pharmacological profile
Authors: Megha S. Jadhav  , Prashant S. Malpure  , Jayshree R. Rajole  , Urmila D. Nikam  , Krushna R. Ranade
Published: March 2023

Catharanthus roseus (Vinca plant) is an important plant having many medicinal uses. It is popularly known as Madagascar periwinkle. It is small in size perennial herbaceous evergreen plant that was native to the Madagascar island .It has attracted increasing attention due to it being shown to possess a range of phytochemicals with various biological activities such as antioxidant, antibacterial, antifungal, antidiabetic and anticancer properties. It delivers about 130 alkaloids predominantly ajmalcine, vinceine, resperine, vincristine, vinblastine and raubasin. Remarkably, vinblastine and vincristine isolated from this plant were the first plant-derived anticancer agents deployed for clinical use. This paper provides an overview of the traditional use and phytochemical profiles of C. roseus, and summarises updated techniques of the preparation of dried material, extraction and isolation of bioactive compounds from this plant. In addition, purported health benefits of the extracts and bioactive compounds derived from this plant were also addressed to support their potential as therapeutic agents.
Load allocation of nutrients causing eutrophication and their impact to lake: Case study of Menjer Lake, Wonosobo, Indonesia
Authors: Agatha Sih Piranti  , Nur Arina Firmahaya  , Dwi Sunu Widyartini  , Ani Widyastuti
Published: March 2023

The purpose of this study was to examine impact of input of nutrients from the catchment to the level of pollution of Lake Menjer Wonosobo. The method was carried out quantitatively by calculating the allocation of pollutant loads from human activities. The water quality status was assessed using the storet method. The highest total P entering Menjer Lake was respectively from agricultural activities, livestock, settlements, and floating net cages. The Menjer Lake was classified as heavily polluted for drinking water, moderately polluted for fish cultivation, and not polluted for irrigation needs.
Geometric Design for Damar Wulan Road Deli Serdang Regency
Authors: Oktaviani Tetra , Gunawan Falwan Rizky
Published: March 2023

Damar Wulan Road is one of the 3.5 km road sections located in Sampali Village, Percut Sei Tuan District, Deli Serdang Regency. This road has the potential to be an access to a strategic location, but there are still few people who use Damar Wulan Road as a mobilization route because most of the road is still subgrade. Therefore, it is necessary to design the Damar Wulan Road so that it can be used by the community. This study aims to design vertical alignment for Damar Wulan Road. The method used for vertical alignment design is TPGJAK 1997. The calculation on the vertical alignment obtained results in the form of 16 PVI arches, which are 8 convex vertical curves and 8 concave vertical curves.
Is a Qualitative Metric of Falsifiability Possible?
Authors: James Dan
Published: March 2023

There is an ever-increasing number of quantitative metrics, most of which are intended to act as proxies of quality for either authors or journals in current scholarly publishing. In contrast, this paper presents a more directly qualitative paper-level metric that adds a falsifiability dimension to the existing methods used to assess scholarly research. This new metric, the "F-index", is derived from a "Falsifiability Statement" (FS) (examples of both are applied self-referentially in Annex A). An FS is a discrete metalevel statement provided by the author/s outlining how their research or assumptions can be foreseeably falsified, and the F-index is a numerical estimate of how clear and practical the steps are to falsify the research or stated assumptions as outlined in the FS. Though the F-index is particularly suited to hypothesis or theory-driven fields, it is also relevant to any empirical inquiry that relies on propositions or assumptions that can be potentially falsified. An F-index is qualitative in that a high F-index number provides a good indication of how novel or original a paper is. Four candidate mechanisms for obtaining an F-index from a Falsifiability Statement are evaluated: a peer reviewer assessed metric, an author or self-reporting metric, a propositional density metric, and an NLP derived metric. This evaluation concludes that a FS is currently a practical proposition, and that the derivation of a meaningful F-Index is an achievable goal.
Programa cuentos de hadas y autoestima en niños de 7 a 10 años
Authors: Velásquez Velásquez Vilma , Lipe Iquiapaza Honoria Gaby , Hualpa Bendezú Bertha Elizabeth , Corimayta Zanabria Livia Milagros
Published: March 2023

La investigación tiene como objetivo determinar la influencia del programa cuentos de hadas en la autoestima de niños y niñas de siete a diez años, a través de la narración de cuentos clásicos. En la investigación se trabajó con una muestra conformada por quince niños de los cuales siete tienen diez años, tres nueve y otros tres ocho; ellos participaron de un taller psicopedagógico, durante tres meses; a quienes se aplicó el Inventario de Autoestima de Coopersmit versión escolar, compuesto por cuatro áreas: sí mismo-general; social-pares; hogar-padres y escuela.  Los resultados muestran que en la aplicación del pre test el 53 % de los niños obtuvieron un promedio bajo de autoestima. En relación al post test podemos observar que el 67% presentaron un alto nivel de autoestima. Se concluye que el programa de cuentos contribuye a mejorar significativamente la autoestima de los niños, tanto en la relación con los demás, en el aprendizaje y en sus emociones.

Palabras clave: cuentos de hadas, desarrollo de habilidades, nivel de autoestima, programa.
Manajemen Madrasah Diniyah Fathul Ulum Puton Diwek Jombang
Authors: Indana Nurul , Munardji Munardji , Kojin Kojin
Published: March 2023

Recognition of Religious Education in the National Education system, of course, will also demand an increase in the management of Religious Education institutions. The implementation of Madrasah Diniyah is accompanied by maximum planning, organizing, implementation, and supervision so that management in educational institutions is getting better and of higher quality. Based on the description above, the management of madrasah diniyah is an important matter to study. This research is a libraryresearch, with data collection techniques through interviews, observation and documentation, using data analysis and triangulation. The results showed that the management of Madrasah Diniyah Fathul 'Ulum Puton Diwek Jombang can be seen from the planning, organizing, movement and supervision. Planning is carried out in consultation with the caretaker of the cottage with the diniyah administrators as well as the ustadz. This plan focuses on the material or program being taught, the management of the madrasah madrasah, as well as the learning process for the madrasah madrasah. Organizing is done by creating an organizational structure according to the abilities possessed. This organizational structure was created to facilitate the implementation of madrasah diniyah. The movement can be seen from the activities of the madrasah diniyah every day which basically contain tafaquh fiddin activities, tahfidzul qur'an and entrepreneurial activities. And supervision is carried out by the head of the madrasah diniyah both vertically and horizontally to control how far this madrasah is running.
Afirmasi Positif Dalam Meningkatkan Self Efficacy Di MA al-Qur’an La Raiba Hanifida Bandung Diwek Jombang
Authors: El Widad Zuha , Idawati Khoirotul
Published: March 2023

Acceleration in the world of education is needed to keep pace with the unstoppable acceleration of world development, not a few people call for success starting from belief, but they are surprised by the success of others and tend to be unsure of themselves/not sure they can. Therefore, it is necessary to have self-confidence in success (self-efficacy) which is raised through positive affirmations. This study uses a qualitative approach with a case study type of research. Data collection techniques using observation, interviews, and communication studies. The application of positive affirmations at Madrasah Aliyah al-Qur'an La Raiba Hanifida consists of 3 categories, namely the slogan and jargon “Future Leaders, Creators of Civilization”, positive affirmations in the form of spiritual activities and reading 3 Greetings of Commitment. Obstacles that arise come from internal (belief system rejection)
Plasma Histone Deacetylase activities, Lipid Profile, and Glycated Haemoglobin levels as indicator of Glycemic control in Type 2 Diabetes Mellitus
Authors: Olooto Wasiu Eniola , Ayodele Monisola A , Soola Joseph O , Adenusi Hammed A , Agidingbi Frank E
Published: March 2023

Background: The number of people with Diabetes mellitus (DM) is steadily rising globally and its socio-economic effects extend beyond the individual to affect their families and whole societies.Aim: This study aimed at determining the Plasma Lipid Profile, Glycated Haemoglobin (HbA1C) and Histone Deacetylase (HDAC) enzyme activities as indicator of Glycaemic control in Type 2 Diabetes mellitus.Methods: A total of 100 newly diagnosed DM patients and 50 control subjects were recruited. The weight, height, body mass index (BMI), waist circumference (WC), and blood pressure of each participant were determined. Also, fasting plasma glucose (FPG), triglycerides, total Cholesterol (TC), high density lipoprotein (HDLC) and HDAC activities were measured using standard methods. Low density lipoprotein (LDLC) was computed.Results: A significant increase in mean age, FPG, systolic and diastolic blood pressure, HbA1c total cholesterol, triglyceride, and low density lipoprotein, and HDAC activities; and a decrease in plasma HDLC were observed among the diabetics when compared with the controls. A direct but significant correlation existed between HDAC activities and FPG, WC, and duration of diabetes; and between HbA1C and FBG, TC, LDLC, HDLC, and duration of diabetes; a direct but non-significant correlation existed between HDAC and HbA1C, HDLC; an inverse and significant correlation existed between BMI and TC, Triglyceride and LDLC.Conclusion: It could be inferred from thia study that plasma HDAC activities is directly related to FPGÂ  as it was found to increase with increasing FPG, indicating its likely role in metabolism.
Case report: Anton's syndrome due to ishemic cerebrovascular disease
Authors: Muratovic Ajla , Vidovic Mirjana
Published: March 2023

Anton's syndrome (AS) describes the condition in which patient deny their blindness despite objective evidence of visual loss, and moreover confabulate to support their stance. It is a rare extension of cortical blindness in which, in addition to the injury to the occipital cortex, other cortical centers are also affected, with patients typically behaving as if they were sighted. This case presents a 76-year-old patient with verified cortical blindness as a result of a stroke. The patient persistently denied vision loss. At the same time, she confabulated to see people and objects in her environment clearly. This syndrome may be unrecognized in routine neurological practice. A suspicion of cortical blindness and AS should be considered in patients with atypical visual loss and evidence of occipital lobe injury. Cerebrovascular disease is the most common cause of AS, as in our patient. Recovery of visual function will depend on the underlying etiology, with cases due to occipital lobe infarction after cerebrovascular events being less likely to result in complete recovery. Management in these circumstances should focus on secondary prevention and rehabilitation.
Localization and type of acute stroke in relation to sleep apnea
Authors: Kojic Biljana , Dostovic Zikrija , C. Ibrahimagic Omer , Smajlovic Dzevdet , Hodzic Renata , Iljazovic Amra
Published: March 2023

Background: More than 50% of stroke patients have sleep-disordered breathing.Aim: To determine whether the location and type of stroke affect the occurrence of sleep apnea.Patients and methods: We analyzed 110 patients with acute stroke and verified sleep apnea. Acute stroke has been verified either by computerized tomography or magnetic resonance imaging of the brain. Average age was 65.13Â±9.27 years and it was 59% men. Number of patients without apnea in control group was the same as well as gender distribution, with average age 64Â±8.69 years.Results: Apnea was verified in 22% patients. The largest number of patients with and without apnea had ischemic stroke 83.6%, while 16.4% of patients had hemorrhagic stroke. Of these, there were 86.2% men and 80% women with ischemic and 13.8% men and 20% women with hemorrhagic stroke. With apnea, the largest number had a lesion in two or more places 51.8%,as well as without apnea 45.45%, but the difference was not statistically significant. According to the acute stroke, the largest number of patients with and without apnea had lesions in the left and right hemispheres 45.4%. There was no statistically significant association between apnea and localization of stroke in the left or in both hemispheres. There is a statistically significant association of AS localization in the right hemisphere with the occurrence of apnea.Conclusion: There is a statistically significant association between the localization of stroke in the right hemisphere and the occurrence of apnea.
Spontaneous hemorrhage in severe forms of Covid 19 infections
Authors: Pasic Fuad , Elezovic Haris , Omerovic Maid , Pasic Amela
Published: March 2023

Background: This research paper is an expression of a desire to view COVID 19 from the perspective of a spontaneous hemorrhage induced on different organ systems. Introduction of a stratified approach to the problem of hemorrhage has become an imperative in medical treatment. Aim: To determine the real figure of spontaneous hemorrhage cases in severe forms of infections caused by Covid 19.Material and methods: The research included 745 patients that suffered from severe forms of infections caused by Covid 19 who were treated in a Respiratory clinic in Tuzla University Clinical Center during 2020 and 2021. The spontaneous hemorrhage was determined on the grounds of laboratory parameters of blood counts and CRP, hemodynamic monitoring of TA and pulse, and CT imagining diagnostic technique.Results: The study presents information about the medical treatment outcome in the case of 5 patients (0,67%) who experienced spontaneous hemorrhage as a part of Covid 19 infection in relation to the total number of 745 patients who were treated during that period in the Respiratory clinic as Covid patients with severe forms of infection. Out of 5 patients who acquired spontaneous hemorrhage 3 were operated. For 4 patients the outcome was lethal. One of the female patients who was in the group of those who were not operated and who had undergone a conservative treatment has survived. In our group of analyzed patients two patients suffered from the hematoma of the front abdominal wall, two had retroperitoneal hematoma and one patient acquired hemorrhage in the abdomen and thoracic with the developing DIC.Conclusion: Relatively low percentage of cases developing spontaneous hemorrhage 5 (0, 67%) but relatively high mortality rate in the cases where it did occur, 4 out of 5 monitored patients, requires certain suggestions that are being presented in this study as to how to approach the cases of spontaneous hemorrhage in the severe forms of Covid 19 infections in more consistent manner in order to improve the outcome of the medical treatment of these cases.
District and City Clasterization Based on Adipura Assessment in The Region of Indonesia Using the Fuzzy Methodc-Means
Authors: Alim Syariful , Hidayat M Mahaputra , Adityo R Dimas , Wilinda Elta Deka
Published: March 2023

Adipura is an award for Indonesian cities that succeed in cleanliness and management of the urban environment. Adipuraisorganizedby the State Ministry ofEnvironment.Adipurais actually usedasatool to encourage the motivation of government officials and the community to improve and improve environmental hygiene conditions in Indonesia. The problem istodeterminetherecipient ofAdipuratakes2weeksto selectRegenciesandCities in all regions of Indonesia, in this study there were 374 Cities and Regencies collected. Clustering is a method of grouping based on the size of closeness (similarity). Clustering is different from a group, if a group means the group is in the same condition, if not, then definitely not the group. One method that can be usedin clusteringis fuzzy c-means. In the concept ofFuzzyC-Means firstdetermine the center of the cluster, which will mark the average location of each cluster which is then carried out the process of repairing the cluster center and the degree ofmembership of the point to theminimization of objective functions that describe the distance from the data points given to the center of the weighted cluster by the degree of membership of that point. From the results of testing a regional clustering systemthat deservesAdipura with the result that each cluster in each processgets avalue that is always changing, so it cannot determine the labeling of a patent. Data greatly influences the time for application processing. The more data it will take more time for the fastest time is in the Big City category while the longest application execution time is in small cities with a total data of 273.
Study Program Classification System Informatics Engineering of Ubhara Surabaya
Authors: Septiana Wahyu Dyah Rizki , Prasetyo Eko , Purbaningtyas Rani
Published: March 2023

One indicator to improve the quality of a university is the number of students who graduate on time. But the problem that often occurs at Bhayangkara University in Surabaya is the number of students entering and the number of students graduating unbalanced. Therefore this research was made to classify the period of study of students by using variables in the form of social studies semester 1-4, school origin, work status, morning / evening class status, and sex. This study aims to classify the length of time a student studies on time or late using the naïve bayes method. The results of this study indicate that the system is able to classify training data and test data on experiments conducted in each batch, the highest accuracy results are 59% and the lowest accuracy results are 56%.
System for Determining House Credit Recipients Based on Data of Cooperative Members Using Simple Additive Weighting (SAW)
Authors: Herulambang Wiwiet , Setyatama Fardanto , Zulfikkih Muhammad
Published: March 2023

PMS Employee Cooperative is a savings and loan cooperative which aims to provide storage and loan services to employees who work at PT. Pro Manunggal Solusi and does not yet have a Decision Support System (SPK). A decision support system is needed in determining the eligibility of cooperative loans to employees. This study aims to help simplify and accelerate and minimize errors that occur in the cooperative borrower feasibility assessment process. The method used for this decision is to use the Simple Additive Weighting (SAW) method. Six criteria are used for the loan eligibility assessment process, namely criteria 1 (Loan size), criterion 2 (Loan Purpose), criterion 3 (Salary), criterion 4 (Position), criterion 5 (Age), criterion 6 (Period of service). Based on the results of the calculation, it can be concluded that each loan employee will be approved according to the ranking and is limited by the balance. If the balance is sufficient, the loan will be approved, but if the balance is less, the loan will be rejected. Of the total value of the ranking results, loans approved with a sufficient balance were Susanto (0.82) with a 12.13% chance, Sentot Sudiyantono (0.80) with a probability of 11.83%, and Siswandi (0.73) with big chance 10.80%.