bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Level of Sensitization on Gait in Chronic Low Back Pain: Insights from a Machine Learning Approach
Authors: Zheng Xiaoping , Reneman Michiel , Echeita Jone Ansuategui , Preuper HR Schiphorst , Kruitbosch Herbert , Otten Egbert , Lamoth Claudine
Published: May 2021

Background: Despite central sensitization (CS) often presents in patients with chronic low back pain (CLBP), there is a lack of quantitative and qualitative analysis of the effect of CS on gait performance. The study aimed to investigate the daily-living gait performance of patients with CLBP with low and high CS levels (CLBP- and CLBP+, respectively). Method：Forty-two patients with CLBP were included. CS was assessed by Central Sensitization Inventory (CSI). Patients were classified according to low or high CSI score (23 CLBP- and 19 CLBP+). Patients wore a 3D accelerometer for about one week. From each patient, 4 days of accelerometer-data were randomly selected. For each day data, continuous gait cycles were extracted using a Fast Fourier Transform-based and a zero-cross method. For all gait cycles in one day, 36 gait outcomes representing variables related to pace, regularity, smoothness, local stability and predictability of gait were calculated. A Random Forest classifier was trained to classify CLBP- and CLBP+ groups based on gait outcomes and SHapley Additive exPlanations (SHAP) method was used to explain the differences between groups in gait outcomes. Results：The Random Forest classifier could accurately recognize the CLBP- and CLBP+ groups (accuracy = 84.4%, F1-score = 82.6%). SHAP reported that the most differences between CLBP- and CLBP+ groups were: index of harmonicity-vertical and harmonic ratio-mediolateral (gait smoothness), stride frequency variability- mediolateral/anteroposterior, stride length variability (gait variability), stride regularity-mediolateral (gait regularity), maximal Lyapunov exponent-vertical/mediolateral and maximal Lyapunov exponent per stride-vertical (gait stability), and sample entropy-anteroposterior (gait predictability). Conclusions： CLBP- and CLBP+ presented different motor control strategies. CLBP- presented a more “loose” control, including higher gait smoothness and stability. CLBP+ presented a more “tight” control, including a more regular, less variable and more predictable gait pattern.
The long noncoding RNA ADIPINT is a gatekeeper of pyruvate carboxylase function regulating human fat cell metabolism
Authors: Kerr Alastair , Kwok Kelvin , Ludzki Alison , Langin Dominique , Dahlman Ingrid , Arner Peter , Gao Hui
Published: May 2021

The pleiotrophic function of long noncoding RNAs (lncRNAs) is well recognized, but their direct role in regulating metabolic homeostasis is less understood. Here, we describe a human adipocyte-specific lncRNA, ADIPINT, which regulates pyruvate carboxylase (PC) an enzyme pivotal to lipid/carbohydrate metabolism. With a novel approach, Targeted RNA-protein identification using Orthogonal Organic Phase Separation (TROOPS), we show that ADIPINT binds to PC in vivo. ADIPINT knockdown alters the mitochondrial interactome of the enzyme leading to reduced activity. Decreases in ADIPINT levels reduces adipocyte lipid synthesis and breakdown as well as cellular bioenergetics. In human white adipose tissue, ADIPINT expression is increased in obesity and linked to insulin resistance. Changes in ADIPINT expression tightly correlate with adipose PC activity and variations in fat cell size, insulin sensitivity or the amount of adipose tissue. Thus, we identify ADIPINT as an important regulator of lipid and energy metabolism in human white adipocytes.
"form follows function"? Erfahrungen zum ersten Semester digitaler Lehre in der Germanistik
Authors: Klanke Katharina
Published: May 2021

Nachdem unter großem Zeitdruck ein Semester mit digitaler Lehre aus dem Boden gestampft werden musste, möchte ich aus Studierendensicht einen Blick zurück auf die vergangenen Monate März bis Juli 2020 werfen. Dabei ist es mir wichtig, zum einen konkrete Methoden und Instrumente zu beleuchten und zum anderen – im Rahmen der von mir besuchten Seminare (sowie im Austausch mit anderen Studierenden) – ein allgemeineres Resümee zu ziehen, wie digitale Lehre für (hoffentlich) alle gelingen kann.
Asynchronität und Interaktivität in der Lehre
Authors: Sieg Christian
Published: May 2021

Bevor ich auf meine eigene Lehre zu sprechen komme, möchte ich eine kleine Akzentverschiebung vornehmen und hoffe, damit vielleicht doch noch einen neuen Punkt in die Diskussion einbringen zu können. Am Anfang meiner Ausführungen steht eine hochschuldidaktische Perspektive, die dazu beitragen soll, nicht vorrangig die technische Umsetzung oder praktische Planung von asynchronen Lernphasen zu beleuchten, sondern die Aufmerksamkeit auf Lernprozesse zu lenken. Als Frage formuliert: Was motiviert die Lernenden zum Lernen? Das betrifft nicht nur die digitale Lehre. Ich schließe damit an die Debatten der Hochschuldidaktik an, die sich in den letzten Dekaden zum Ziel gesetzt haben, die Aktivität von Lernenden zu steigern. Zentral ist dabei die Wende vom Lehren zum Lernen – bzw. vom teaching zum learning, wie es in der international geführten Debatte heißt. Wesentlich für diesen Paradigmawechsel ist das neue Interesse am studentischen Lernprozess: die Studierendenzentrierung. Übernimmt man als Dozierender Verantwortung für den ganzen Lernprozess und nicht nur für den Ablauf des Seminars, dann ergibt sich ein fundamental neues Selbstverständnis für Lehrende.
Neuere und neueste digitale Literatur in Forschung und Lehre: Der 'digital turn' als Chance für die Germanistik
Authors: Berg Gunhild
Published: May 2021

Der Beitrag plädiert dafür, den 'digital turn', der weite Teile der germanistischen Lehre spätestens im 'digitalen' Sommersemester 2020 erreicht hat, als Chance zu verstehen, das Fach in der Verbindung von Forschung und Lehre unter den Bedingungen des Digitalen neu zu denken und zukunftsorientiert zu profilieren. Digitalisierung formatiert (auch) in der Germanistik sowohl Forschungsgegenstände und Methoden als auch die Möglichkeiten ihrer Vermittlung in der Hochschullehre als einem Teil der Wissenschaftskommunikation. Doch Digitalisierung bewirkt weniger eine technische Ausstattung als vielmehr eine Kultur der Digitalität.
Flipped Classroom als kompetenzorientierte Perspektive für literaturwissenschaftliche und -didaktische Seminare: Ein Praxisbericht
Authors: Bernhardt Sebastian
Published: May 2021

In seinem Praxisbericht zeigt Sebastian Bernhardt in einem ersten Schritt, welche Konsequenzen die pandemiebedingten Veränderungen kurzfristig auf seine akademische Lehre hatten. Die Erfahrungen in der notgedrungen rein digitalen Lehre münden aber in einem zweiten Schritt in nachhaltige Perspektiven für die akademische Lehre, die sich nicht auf das Gegensatzpaar digital vs. präsent reduzieren lassen. Zentral ist, dass die Erfahrungen mit digitalen Flipped Classroom-Modellen sich auch in die Zeit nach Corona übertragen lassen, sofern digitale und präsente Vermittlungsanteilen langfristig und kompetenzorientiert miteinander verknüpft werden. Dabei soll weder das eine gegen das andere ausgespielt werden noch eine Digitalisierung um ihrer selbst willen, sondern eine Passung von Vermittlungsziel und Medium, hergestellt werden. Wie er im Folgenden zeigt, konnte er aus der Not der Situation geboren Erfahrungen sammeln, bei denen deutlich wurde, dass einige digitale und asynchron angelegte Flipped Classroom-Formate in Kombination mit synchronen Zoom-Sitzungen, die langfristig durch Präsenzphasen ersetzt werden, einen nachhaltigen Kompetenzerwerb erzielten und zu einer Individualisierung von Lernwegen bei den Studierenden führten.
Blended-Learning-Szenarien in der Germanistik: Erfolgsfaktoren illustriert am Beispiel "Wikis statt Referate"
Authors: Kleinwort Malte
Published: May 2021

Trotz der großen Bandbreite unterschiedlicher Blended Learning-Szenarien können für die Bereiche Konzeption, Kommunikation, Motivation und Durchführung konkrete Aspekte und Tipps formuliert werden. Beispielhaft kann das anhand eines im Sommersemester 2017 entwickelten Lehrkonzepts erläutert werden, das in drei weiteren Lehrveranstaltungen wiederholt und optimiert worden ist. Bei dem beispielhaften Lehrkonzept handelt es sich um "Wikis statt Referate". Die Studierenden präsentieren in einem Gruppen-Wiki - an einem Wiki arbeiten 3-5 Studierende - nach konkreten Vorgaben Informationen des jeweiligen Wiki-Gegenstands mit direktem Bezug zum Seminarthema. Die Wiki-Gegenstände werden im letzten Drittel des Semesters auch zu Sitzungsthemen. Bei mir waren Wiki-Gegenstände meistens literarische Werke, die in Beziehung zum Seminarthema gesetzt wurden. Die in den Wikis versammelten Informationen erleichterten den Studierenden die Vorbereitung der mündlichen Prüfungen und Hausarbeiten. Im Folgenden werde ich zur Erläuterung der Problemlage entgegen dem üblichen Vorgehen nicht auf Good Practice-, sondern auf Bad Practice-Beispiele zurückgreifen, weil sie erfahrungsgemäß sehr gut dafür geeignet sind, für konkrete Probleme zu sensibilisieren.
Offenheit: OERs, Creative Commons und die Zukunft germanistischer Lehre und Forschung
Authors: Stüssel Kerstin
Published: May 2021

Der vorliegende Text zeigt die Position einer Autodidaktin bzw. Dilettantin: Zwar habe ich mich schon früher in verschiedenen Lehr-Settings mit Digital Humanities auseinandergesetzt, vor dem Sommersemester 2020 spielte die digitale Lehre aber kaum eine Rolle, es sei denn man zählt die Nutzung unterschiedlicher universitärer e-Learning-Portale (Moodle, Ilias etc.) zur Terminplanung und Materialbereitstellung schon dazu. Gerade weil ich mich als Nachzüglerin begreife, die behelfsmäßig einiges nachzuholen hatte und nur ansatzweise die lange schon existierenden Praktiken und Diskurse kannte, empfand ich den offenen Brief "Verteidigung der Präsenzlehre" als unfair, nicht nur gegenüber denjenigen, die sich jetzt notgedrungen versuchten zu professionalisieren, vor allem aber unfair gegenüber denjenigen, die schon lange intensiv und didaktisch kompetent digitale Elemente erprobt und zu Szenarien des Blended Learning entwickelt haben: Eine Diagnose, die die komplette Ersetzung der Präsenzlehre als latent schon geplante Sparmaßnahme unterstellt und eine Intervention, die aus diesem negativen Szenario heraus die hergebrachte Präsenzlehre mit ihren vielen Lebenslügen meint verteidigen zu müssen, schien mir unangebracht, weil von den elaborierten hochschuldidaktischen Perspektiven in Richtung "digitaler Präsenz" und von den Chancen für die Forschung keine Rede war. Und: Der Aufwand und die technische Implementierung von digitaler Lehre kann, sofern die Qualitätssicherung ernst genommen wird, nicht als Sparmaßnahme durchgehen. Eher im Gegenteil!
CLARIAH-DE in der digitalen Lehre
Authors: Werthmann Antonina , Witt Andreas , Bock Sina , Jannidis Fotis
Published: May 2021

Die durch die Covid-19-Pandemie bedingte Umstellung der Präsenzlehre auf digitale Lehr- und Lernformate stellte Lehrende und Studierende gleichermaßen vor eine Herausforderung. Innerhalb kürzester Zeit musste die Nutzung von Plattformen und digitalen Tools erlernt und getestet werden. Der Beitrag stellt exemplarisch Dienste und Werkzeuge von CLARIAH-DE vor und erläutert, wie die digitale Forschungsinfrastruktur Lehrende und Studierende auch im Rahmen der digitalen Lehre unterstützen kann.
Gelungene Online-Lehre und die digitale Kultur der Germanistik: Perspektiven der Netzliteraturwissenschaft
Authors: Ernst Thomas
Published: May 2021

Zentrale Voraussetzung einer differenzierten Bewertung der germanistischen Online-Lehre wäre, zunächst die Rolle der Germanistik in der digitalen Gesellschaft sowie den Wert digitaler Bildung zu bestimmen. Dazu wiederum wäre es wichtig, das Wissen, die Methoden, die Begriffe und Fragestellungen der Germanistik in ein Verhältnis zu den Potenzialen und Problemen der digitalen Gesellschaft zu setzen. Zwar adressieren Arbeitsgruppen in den Fachverbänden diese Aufgabe, die germanistischen Teildisziplinen gehen damit aber unterschiedlich um. Als Teildisziplin hat somit auch eine medienkulturwissenschaftlich ausgerichtete (Gegenwarts-)Literaturwissenschaft die Pflicht, nach den Folgen des Medienwandels und der vernetzten Kommunikation im World Wide Web für die Literatur, ihren Betrieb und für die literaturwissenschaftliche Forschung und Lehre zu fragen. Auf einer Konferenz zum Thema "Während und nach Corona: Digitale Lehre in der Germanistik" erscheinen vor diesem Hintergrund zwei Fragen besonders relevant: 1. Welche digitalen Standards und Erkenntnisse müsste die Germanistik etablieren, um gelungene Lehre in der digitalen Kultur überhaupt bewerten zu können? 2. Wie wäre ein Teilbereich der germanistischen Literaturwissenschaft als Netzliteraturwissenschaft zu konzipieren, der das notwendige Wissen über die vernetzte Kommunikation in der digitalen Gesellschaft bereithält und zur Etablierung von Standards des digitalen germanistischen Lernens beitragen könnte?
Lektüreseminar online? Social-Reading-Tools als Grundlage für eine mediendidaktische Neukonzeption am Beispiel eines Moduls in einem universitären Masterstudiengang
Authors: Schmohl Tobias
Published: May 2021

In diesem Beitrag wird ein Lektüreseminar vorgestellt, das curricular im Studiengang Higher Education (M.A.) am Hamburger Zentrum für Universitäres Lehren und Lernen (HUL) verortet ist und das konzeptionell nach dem Vorbild eines literaturwissenschaftlichen Lektüre-Seminars entwickelt wurde. Dort bildet es mit dem Modultitel "Wissenschaftsforschung" eines von vier Pflichtmodulen, die thematisch um ein mehrsemestriges Projektmodul sowie ein einführendes Grundlagenmodul gestaltet sind. Ziel des Lektüreseminars ist es, Orientierungswissen zu Grundlagentexten der Wissenschaftsforschung anhand exemplarischer Detail-Lektüre zu gewinnen, diskursiv zu teilen und kritisch einzuordnen. Im Mittelpunkt steht also die systematische wissenschaftliche Textarbeit.
Revisiting the environmental Kuznets curve: Evidence from West Africa
Authors: Silvère Konan Yao , Aklobessi Kodjo
Published: May 2021

This paper analyzes the revenue-pollution relationship by revisiting the Environmental Kuznets Curve (EKC) hypothesis for West African countries over the period of 1980–2014. The study approximates the income measurement by GDP per capita and uses carbon dioxide (CO2), nitrogen oxide (NO2), and methane emissions as various environmental quality measures. The paper uses parametric and non-parametric estimation techniques to test the EKC hypothesis. The results support the existence of the U-inverted relationship between income and methane emission, on one hand, and between income and nitrogen dioxide emission on the other. The estimates also show a mixed result for the U-inverted hypothesis between income and carbon dioxide emissions. Thus, the verification of the curve depends on the estimation techniques and the measurement of the pollutant used. The obtained results led to the conclusion that the EKC hypothesis is validated for West African countries.
Investment potential of non-state pension funds in Ukraine
Authors: Tropina Valentyna , Melnyk Viktor , Rippa Mariia , Yevtushenko Natalia , Rybakova Tetiana
Published: May 2021

World practice shows that non-state pension funds (NPFs) are not only a tool for supplementary pensions, but also a source of significant investment in the economy. This study aims at determining the investment potential of 65 Ukrainian NPFs currently functioning in the country. The analysis of Ukrainian NPFs has shown their insignificant role as an investment resource (the volume of their assets is 0.09% of GDP). At the same time, NPFs operate with significant funds (UAH 3.1 billion in 2019), but the lack of a developed stock market and effective financial instruments in the country narrows the opportunities for their investment activities. A study of the structure of NPF assets allocation showed that it is far from optimal in terms of investment portfolio diversification and is very conservative – almost 85% of invested NPF assets are government guaranteed securities and funds in bank deposit accounts. But in the context of tightening the requirements for disclosure of information on the activities of NPFs, promoting the stock market development, formation of reliable mechanisms to protect depositors’ pension savings,and formation of an effective investment portfolio, NPFs in Ukraine
ULTRASOUND BREAST CANCER SCREENING IN DENSE PARENCHYMA: THE VALUE OF COMPUTER AIDED DETECTION SYSTEM FOR MAMMOGRAPHY (SINGLE-CENTER, PROSPECTIVE, RANDOMIZED CLINICAL TRIAL)
Authors:   Mari State University, Pasynkov D.V. , Tukhbatullin M.G.. ,   Kazan State Medical Academy, Egoshin I.A. ,   Mari State University, Kolchev A.A. ,   Kazan (Volga region) Federal University, Kliouchkin I.V. ,   Kazan Medical University
Published: May 2021

Purpose. To compare the results of screening ultrasound (US) in women with dense (ACR C-D) breast parenchyma, with no suspicious changes at mammography, with and without considering the CAD results during the examination. Materials and methods. We randomized 2078 women aged 40-72 years old for breast US (US group) or CAD + breast US with targeted analysis of the areas marked by CAD on the mammograms (CAD + US group). Results. In the US group we found 16 breast carcinomas (BC) (median: 15 mm, range: 8-24 mm), in the CAD + US group – 22 BCs (median: 10 mm, range: 5-24 mm). 3 of the 16 BCs (18.75%) in the US group and 11 of 22 (50.00%) BCs in the CAD + US group (р<0.05) were less than 1 cm. BCs were revealed only during the targeted scanning of the CAD marking area in 5 of 11 women, and all these BCs were ≤1 см. The rate of benign lesions required biopsy was 76 of 1039 (7.31%) – in the US group and 68 of 1039 (6.54%) – in the CAD + US group (р>0.05). During the 3-year follow up we found 9 more BCs in the US group and 2 more BCs in the CAD + US group (p<0,05). Discussion. The probability of ACR C-D parenchyma in another sample of 10000 mammography sets was: 51.61% – in women of 40-44 years old, 37.10% – in women of 45- 49 years old, 13.22% – in women of 50-54 years old, 12.07% – in women of 55-59 years old, 8.41% – ≥60 years old. Conclusion. In the mammographically dense breast parenchyma the targeted ultrasound of the areas marked by CAD as suspicious significantly increased the small BCs detectability and significantly decreased the rate of BCs revealed during the 3-year follow up with no raise of unnecessary biopsy rate.
THE RELATIONSHIP OF STRUCTURAL CHANGES OF THE MYOCARDIUM IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION WITH ST SEGMENT ELEVATION ACCORDING TO CONTRAST MRI DATA WITH THE FEATURES OF CORONARY LESION AND THE TIME OF REPERFUSION THERAPY
Authors:   National Medical Research Center of Cardiology, Terenicheva M.A. , Shakhnovich R.M. ,   National Medical Research Center of Cardiology, Stukalova O.V. ,   National Medical Research Center of Cardiology, Butorova E.A. ,   National Medical Research Center of Cardiology, Ternovoy S.K. ,   National Medical Research Center of Cardiology
Published: May 2021

Purpose. To study the relationship between the characteristics of acute myocardial infarction and ST-segment elevation (infarction size, microvascular obstruction) according to contrast cardiac MRI data with the features of coronary lesion and the time of percutaneous coronary intervention. Methods. The study included 52 patients with acute ST-segment elevation myocardial infarction (MI) who were admitted to the hospital in the first 48 hours after the onset of the disease and underwent primary percutaneous coronary intervention (pPCI). On Days 3-7 contrast-enhanced cardiac MRI was done. Tissue analysis of scans was performed evaluating infarct size, presence and size of microvascular obstruction (MVO). Results. Patients were divided into 2 groups separated by the median time to reperfusion treatment (3 hours). There were no significant differences between groups in MRImeasured ejection fraction (EF) (in the group with later pPCI >3 hours of symptom onset EF was 49.0 ± 11.0%, and in the comparison group – 45.7 ± 10.5%, р=0,2). MRI-measured infarct size was significantly higher in the group where pPCI was done >3 hours of symptom onset: 18.1 ± 1.7% of the left ventricular mass, compared to the early reperfusion group – 10.9 ± 1.9% (р=0.009). MVO magnitude was also higher in the later pPCI group (2.6 ± 0.64% vs 0.03 ± 0.3% in the comparator group), (р<0,027). Correlation analysis also revealed a reliable relationship between infarct size and time to reperfusion (R 0.381, p=0.006). LAD lesions were associated with higher infarct size values (p=0.02) and higher risk of MVO (odds ratio 2.9, CI 0.83-10.0, р=0.03). Complete occlusion of infarct-related artery (IRA) was associated with higher infarct size (16,97±3.3 vs 12.05±1.4, р=0.02). There was no reliable correlations between IRA patientcy and MVO magnitude (р=0.7). Conclusions. In this study timing primary percutaneous coronary intervention, in groups of below and more than 3 hours after symptom onset, had no significant impact on ejection fraction, as determined by MRI. However, primary percutaneous coronary intervention timing exceeding 3 hours significantly influenced infarct size, the occurrence and magnitude of microvascular obstruction. LAD being the infarct-related artery was associated with larger infarct size, higher risks of microvascular obstruction development. The absence of complete occlusion of the infarct-related artery was associated with a smaller myocardial infarction size according to MRI data.
MAIN VEIN THROMBOSIS IN THE PRACTICE OF AN INTENSIVE CARE DOCTOR
Authors:   N.I. Pirogova Russian National Research Medical University, Bykov M M.V. , Madorsky K.S. ,   Moscow Scientific Research Institute of Emergency Pediatric Surgery and Traumatology, Semenov N.Yu. ,   Moscow State Budgetary Healthcare Institution Morozovskaya Children's Clinical Hospital, Zubareva E.A. ,   N.I. Pirogova Russian National Research Medical University, Marushchak E.A. ,   Central Clinical Hospital of the Russian Academy of Sciences, Bagaev V.G. ,   Moscow Scientific Research Institute of Emergency Pediatric Surgery and Traumatology, Lazarev V.V. ,   N.I. Pirogova Russian National Research Medical University, Krylova A.A. ,   Moscow, Infectious Clinical Hospital No. 2, Mayorov A.D. ,   GBUZ MO MOZOMD
Published: May 2021

Purpose. To draw the attention of specialists to the question of incidence of catheterassociated and catheter-induced thrombosis in patients in intensive care units. To assess methods of visualization and monitoring of the great veins state using ultrasound. To evaluate various links in the pathogenesis of thrombus formation and the possibilities of prevention and treatment. Materials and methods. More than 3500 ultrasound examinations have been performed in over 850 patients, both in the ICU and after the transfer of patients to specialized departments. The study included children aged from 1,5 months to 18 and adults, with one or more central venous catheters (CVCs). In the absence of contraindications, patients received prophylactic anticoagulant therapy (heparin at a dose of 50-100 U/kg/day). Ultrasound was performed with a frequency of 4 to 85 times in one patient, depending on the detection and severity of CAT. The studies were carried out in B-mode using color and/or energy mapping on ultrasound scanners Philips HD 11 (Philips, USA), SonoSite MicroMaxx (USA), Logiq E8 (GE, USA), Mindrey M 7 (Mindrey, China), Samsung HM 70 (Samsung, South Korea) using linear multi-frequency sensors 10-16 MHz. The patients underwent a complex ultrasound examination of the superior or inferior vena cava (depending on the assumed main vein thrombosis (TMV) localization), as well as the main veins of the extremities. Conclusions. The multifactorial nature of TMV development in ICU patients requires increased alertness to this complication, which necessitates ultrasound monitoring of the great veins in patients in intensive care units with installed CVCs. It should be noted that, despite the ongoing prophylaxis of TMV (including the use of anticoagulants), there is still a high risk of their development.
SYSTEM OF A UNIFIED APPROACH TO INTERPRETATION OF MAGNETIC RESONANCE TOMOGRAPHY IN DIAGNOSTICS OF PATHOLOGICAL PLACENTAL ATTACHMENT "MAPI-RADS" (MORBIDLY ADHERENT PLACENTA IMAGING REPORTING AND DATA SYSTEM)
Authors:   Research Center for Obstetrics, Gynecology and Perinatology, Uchevatkina P.V. , Bychenko V.G. ,   Research Center for Obstetrics, Gynecology and Perinatology, Kulabukhova E.A. ,   Research Center for Obstetrics, Gynecology and Perinatology, Luzhinа I.A. ,   Research Center for Obstetrics, Gynecology and Perinatology, Shmakov R.G. ,   Research Center for Obstetrics, Gynecology and Perinatology
Published: May 2021

Purpose. Assessment of the capabilities of MRI in the diagnosis of placenta invasion, study of the value of diagnostic signs of placental invasion. Development of a unified scoring system for the received data "MAPI-RADS (Morbidly Adherent Placenta Imaging Reporting and Data System)". Material and Methods. The retrospective study is based on an analysis of the results of MRI in 212 pregnant women with placenta accreta performed at 26-34 weeks of gestation. Evaluation of images and signs of invasive placenta, correlation analysis with intraoperative data were carried out. To validate the significance of diagnostic features as predictors of placenta accretion, a statistical analysis of the data obtained was performed to determine the frequency of occurrence of each feature, and a mathematical calculation of the value of each criterion obtained, expressed in points. Results. Diagnostic criteria have been developed, divided into 2 groups. The main criteria (diagnostic value 2 points): bulging of the uterine wall with prolapse of the lower uterine segment; thinning of the myometrium in the area of attachment of the placenta; the presence in the structure of the placenta of vascular "lacunae"; the presence of vascular "ribbons"; retroplacental hypointense "shadow". Additional criteria (1 point for the first and second, 3 points for the third criteria): vascular plethora and varicose veins of the uterine wall; central/marginal placenta presentation; the spread of the placenta outside the uterine wall (with pl.percreta). For the final diagnosis, the MAPI-RADS system was developed, which consists in summing the scores obtained during the interpretation, with the class of pathological attachment of the placenta being set. Conclusions. The developed system "MAPI-RADS" allows identifying, systematizing and quantifying the signs of placenta invasion obtained during the study, and makes it possible to set a class corresponding to the degree of placental ingrowth, correlating with intraoperative data.
THE EFFECTIVENESS OF ORBITAL VOLUMES CALCULATIONS AFTER TRAUMATIC INJURIES BASED ON CT DATA
Authors:   The Peoples' Friendship University of Russia, Davydov D.V. , Serova N.S. ,   I.M. Sechenov First Moscow State Medical University, Pavlova O.Yu. ,   I.M. Sechenov First Moscow State Medical University
Published: May 2021

To present a case of a 56 y.o. male with maxillo-facial trauma after falling from heights and the possibility to choice the treatment tactics based on CT volume calculation. Material and methods. Patient N., 56 years old, came to the clinic 3 days after the injury – a fall from heights. During the examination in the clinic, the patient did not have visual impairments and difficulties in eye movement. We performed MSCT of the maxillofacial region, which revealed radiological signs of fractures of the lower and lateral walls of the right orbit. In order to determine further treatment tactics for this patient (surgical treatment or conservative therapy), the authors performed additional processing of MSCT data in order to obtain clarifying diagnostic information. Results. The authors performed the calculation of orbital volumes and confirmed the possible minimal risk of post-traumatic complications such as enophthalmos and hypophthalmos. It was decided to treat the patient conservatively. The long-term follow-up MSCT study confirmed the correct management of a patient with orbital trauma in terms of restoration of the right orbit walls with minimal volumetric change. Conclusion. This case highlights the advantage of using new techniques of CT data processing in daily practice.
Efectos a un año de un programa educativo en el control metabólico de pacientes con diabetes de un servicio especializado en un hospital nacional peruano
Authors: Paz-Ibarra José Luis , Alatrista García Cesar
Published: May 2021

Objetivo: determinar los efectos en el control de la diabetes durante un año de seguimiento de un grupo de pacientes que recibieron un programa educativo añadido al tratamiento habitual en la consulta ambulatoria especializada del Hospital Nacional “Edgardo Rebagliati Martins” en Perú. 
Metodología: estudio cuasiexperimental en el que se distribuyeron 90 pacientes en dos grupos: intervención o control. El primero recibió cuatro sesiones educativas en grupos de cinco a ocho participantes. Se procuró que la terapia farmacológica se mantuviera sin modificaciones significativas tres meses antes y durante todo el seguimiento. Se determinaron los cambios en los parámetros clínico-bioquímicos principalmente HbA1c al inicio, a los seis y 12 meses después de la intervención.
Resultados: todos los pacientes completaron todas las sesiones, así como las consultas de seguimiento con la respectiva toma de muestras para la determinación de los parámetros bioquímicos. En el grupo de intervención la HbA1c disminuyó 1,2 % a los 12 meses, mientras el grupo control presentó un incremento de 0,5 %. El peso, la glicemia en ayunas y el colesterol LDL también disminuyeron durante el seguimiento; el porcentaje de pacientes que alcanzaron las metas de HbA1c aumentó en 22 % y de LDL en 11 % a los 12 meses de seguimiento.
Conclusiones: un programa de educación diabetológica añadido al manejo convencional especializado en un hospital nacional de referencia mejoró el control metabólico durante un año de seguimiento.
Transport and infrastructure aspect of urban environment transformation in millionaire cities of Russia (on the example of railway transport in Perm)
Authors:   Perm State University, Merkushev Sergey A. , Nikolaev Roman S. ,   Perm State University, Luchnikov Andrey S. ,   Perm State University, Kutergina Galina V. ,   Perm State University
Published: May 2021

One important field of modern complex research is the study of urban area transformation processes under the significant influence of changes in transport infrastructure, including railway infrastructure. Using the comparative method and the method of integral scoring, the authors of the article have evaluated how well suburban railway transport is developed in 14 millionaire cities of Russia. A special focus is on Volgograd, Krasnoyarsk, Samara and Kazan, which are all similar to Perm in terms of territorial and planning characteristics. One trend in organizing urban traffic is to develop off-street and high-speed transport (including railways), which is particularly important to Perm as the city is stretched along the Kama River. In the article we reveal that Perm has a high potential for increasing the role of railway transport in urban traffic organization. However, that potential is not fully reached because of the unsystematic approach to managing suburban railways at the regional and municipal levels; this has negative budgetary, financial, spatial and temporal consequences. The authors state that the project to eliminate the railway line from the station “Perm II” to the railway stop “Motovilikha” initiated by the regional authorities has negative consequences. It worsens the integral indicator characterizing the level of suburban railway transport development in the center of Perm Region and makes commuting longer and less comfortable for passengers. Also, it makes public transport in Perm less effective in terms of the city budget. The project will force people to use private cars and will make the city transport system less rational. Although the authorities state that the railway line hinders the integration of the Kama river embankment into the urban space, the authors of the article have not found sufficient evidence in support of that argument.
Spatial relationships of the local community (the case of the village Pronino, Vesiegonsky district, Tver region)
Authors:   Tver State University, Smirnov Ilya P. , Vinogradov Dmitry M. ,   Tver State University, Alekseev Alexander I. ,   Lomonosov Moscow State University
Published: May 2021

The article is devoted to topical issues of the study of population migration at the local level. On the example of a specific rural settlement — the village of Pronino, Vesyegonsky district — the spatial relations of the rural community are considered. The article gives a comprehensive description of the village of Pronino over the past 150 years. The influence of the geographical factor on the development of the settlement is estimated, specialization is analyzed, and trends in demographic development are considered. A relationship is established between the evolution of the functions of a settlement and the change in its population. Based on the data from field studies, the real ties of local residents with other settlements and regions are analyzed. Most of the inhabitants of Pronino are natives of the village and the surrounding settlements. A completely opposite picture is observed in the distribution of Pronino inhabitants’ children who move. Most of the children moved to St. Petersburg or Vesyegonsk. In recent years, migration trends have changed, and more and more children of local residents choose the regional capital — Tver. The geography of subscribers of the virtual community of the village of Pronino in the social network VKontakte largely reflects the real spatial relations Most of the community’s subscribers live in St. Petersburg; in second place, the district center, Vesyegonsk; in third place, Tver. A comparison of field research data and data from social networks allowed us to conclude that the virtual mobility of the rural population has spatial trends almost the same as real ones. Particular attention is paid to the seasonal migration of the population, using a survey of summer residents who identified their permanent residence and the main reasons for choosing Pronino. The survey data confirmed the hypothesis that the target users of the “distant summer cottages” are natives of these settlements.
Age and chronostratigraphic position of lacustrine-bog deposits in the Chernaya River basin in the north of the Bolshezemelskaya tundra according to the results of their 230Th/U- and 14C-dating
Authors:   St. Petersburg State University, Maksimov Fedor E. , Andreicheva Ludmila N. ,   Institute of Geology named after Academician N. P. Yushkin of Komi Science center of Ural Branch of the Russian Academy of Sciences, Kuznetsov Vladislav Yu. ,   St. Petersburg State University,   Herzen State Pedagogical University of Russia, Grigoriev Vasily A. ,   St. Petersburg State University, Petrov Alexei Yu. ,   St. Petersburg State University, Levchenko Snezhana B. ,   St. Petersburg State University, Marchenko-Vagapova Tatyana I. ,   Institute of Geology named after Academician N. P. Yushkin of Komi Science center of Ural Branch of the Russian Academy of Sciences, Baranova Nadezhda G. ,   St. Petersburg State University
Published: May 2021

The main goal of this study was to elucidate the chronostratigraphic position of the sediments of lacustrine-bog stratum from the Ch-14 section located in the sub-latitudinal sector of the Chernaya River in the north of the Bolshezemelskaya tundra. This study presents data on their numerical age and time of their formation, obtained by the parallel 230Th/U and 14С dating of organic-rich layers. According to the results of spore-pollen analysis obtained earlier, the lacustrine-bog sediments were attributed to the Byzovaya (Middle Valdai) interstadial, together with the lake and alluvial deposits from the Ch-3 and Ch-4 sections in the same sector of the Chernaya River. The 230Th/U and 14C age data are in good agreement with each other, especially for the lower boundary of the lacustrine-bog sediments of the Ch-14 section. The time range of the lacustrine-bog stratum accumulation is estimated to be approximately 13.7–13.3 to ~12.0 thousand years ago. Thus, its formation (10.5–6.5 m layer) did not occur in the Middle Valdai, but in the Late Valdai time from the beginning of Allerød to the beginning of the Younger Dryas cooling. It has been suggested that a certain delay of late glacial climatic events took place in the Bolshezemelskaya tundra compared with their age-related estimation by the Greenland isotope-oxygen stages. For the first time, the isochronous approximation approach was applied to obtain the 230Th/U age of such young terrestrial organic-rich deposits. Earlier this approach was usually used in dating similar sediments not younger than MIS-3. The geochronological results presented in this paper allow us to recommend the 230Th/U method for determining the age of late glacial organic-rich deposits and climate events correlated with them.
Consumo e Sustentabilidade em Turismo: panorama, conceitos e métodos aplicados no contexto de pesquisas no Brasil
Authors: Da Silva Melo Sonia Rebouças , Da Silva Minelle Enéas , Sales Melo Francisco Vicente
Published: May 2021

Os conceitos de consumo associados à sustentabilidade geralmente são múltiplos, porém imprecisos e com pouco consenso. No contexto de pesquisas em turismo, isso se torna ainda mais evidente, uma vez que esta área do conhecimento exige um pensamento multidisciplinar. Com foco no conceito de consumo sustentável, o objetivo central deste artigo é compreender como consumo e sustentabilidade são utilizados em pesquisas na área do turismo. Para tanto, foi realizada uma revisão sistemática da literatura de 71 publicações acadêmicas brasileiras no período de 2008 a 2017. Os resultados revelaram que o conceito de consumo utilizado na área de turismo em estudos sobre sustentabilidade tende a ser amplo e, comumente, a definição aborda mais aspectos ambientais e econômicos. Observa-se que nas pesquisas considerando a perspectiva prática da preservação, há uma tendência a não considerar os turistas como agentes desse processo de preservar, isso porque o consumo, nesse contexto, normalmente está voltado para análise das escolhas que as pessoas fazem ao decidirem por um bem ou serviço. Nesse sentido, a ideia de associar o ato de consumir às práticas de sustentabilidade nas destinações é uma das principais propostas para agenda de pesquisas da área.

Palavras-chave: Consumo Sustentável. Turismo. Sustentabilidade em Turismo. Publicações Nacionais.
Voluntariado e democratização no acesso ao turismo por meio da plataforma digital Worldpackers
Authors: Berti Tauwan , Conceição Larissa
Published: May 2021

O presente estudo teve por finalidade estudar as possibilidades de democratização do turismo através da plataforma Worldpackers, uma plataforma digital que facilita a realização de viagens, levando em conta três formas de voluntariado e tendo como ênfase a troca de habilidades por hospedagem. Como abordagem teórica, o trabalho aproxima os campos do turismo (Netto, 2010; Goeldner, 2002) em seus aspectos sociais, culturais e econômicos, e da comunicação Corrêa (2005), o cenário digital e a emergência de dispositivos como as plataformas de viagens/turismo, e fundamenta-se ainda em perspectivas de estudo da democracia (Habermas 1995; Santos, 2002). O percurso metodológico estruturou-se a partir de pesquisa exploratória Gil (2008), pesquisa bibliográfica Marconi e Lakatos (2003), o estudo de caso com caráter qualitativo Robert Yin (2001), tendo como objeto a plataforma digital Worldpackers, como recorte, a atuação desta organização no Brasil e foco analítico na atuação da plataforma, isto é, a comunicação e estratégias utilizadas com os diversos públicos, visando entender como possibilitam o acesso ao turismo. Para a coleta de dados realizou-se entrevista com um dos fundadores da Worldpackers, bem como aplicou-se um questionário direcionado aos viajantes que já utilizam a plataforma. Como resultados, observa-se a relação entre o surgimento destas plataformas e a busca pelo turismo de experiência, o potencial de outras iniciativas no cenário digital que possibilitam um maior acesso às viagens e, consequentemente, uma possível democratização na prática turística.
Palavras-chave: Comunicação Digital. Democracia. Turismo.
Ensino superior em hotelaria: relação entre formação profissional e prática no mercado de trabalho
Authors: Lins Silva Amanda , Menezes Paula Dutra Leão de
Published: May 2021

O tema educação e trabalho no ensino superior vêm se aproximando em decorrência do reconhecimento das questões inerentes a formação profissional recebida e a adequação com o cotidiano de trabalho. Dessa forma, destaca-se a necessidade de compreender se a formação recebida pelos bacharéis em hotelaria está cumprindo seus propósitos e, ao mesmo tempo, fornecer subsídios para a entendimento da relação entre formação profissional e prática profissional. O presente estudo analisou a relação entre a formação do profissional e prática de mercado de trabalho na perspectiva dos egressos do curso de hotelaria da Universidade Federal da Paraíba. Para tanto, realizou-se uma pesquisa qualitativa descritiva. Para a coleta de dados realizou-se entrevista de Grupo Focal com egressos do curso de hotelaria da UFPB que estão atualmente inseridos no mercado de trabalho em hotelaria. Os egressos expuseram que o curso melhorou com o novo projeto pedagógico de curso e, que atualmente, está caminhando para encontrar uma identidade e avaliam que a transferência do curso do campus de Mamanguape para João Pessoa, bem como a criação do Departamento de turismo e Hotelaria contribuiu para a formação de uma identidade. Segundo os entrevistados faltou na formação mais aspectos relacionados a parte operacional e, sobretudo a prática, elencando como o ponto mais negativo a ausência de laboratórios no curso. Em relação a formação profissional e o mercado de trabalho afirmaram que foi distante, e explicaram que o setor está em crise, que são muitas as mudanças no contexto do mercado e das novas tendências.
Palavras-chave: Ensino Superior.  Formação Profissional. Hotelaria.
A delicadeza e as formas de tratamento em português língua não materna Um estudo de caso numa sociedade bilingue em Espanha
Authors: Antão Marta Alexandra Cação Lopes , De Almeida Carla Aurélia
Published: May 2021

Atendendo ao caráter não universal da delicadeza ou à sua flutuação cultural, o presente trabalho tem por objetivo investigar o desempenho de um grupo de estudantes específico de Português Língua Não Materna quanto às estratégias de delicadeza usadas em atos ilocutórios com uma dimensão diretiva, assim como o uso das formas de tratamento em língua portuguesa. Na análise sociolinguística dos estudantes, destacamos fatores característicos do grupo em observação, como o multilinguismo, a proximidade das línguas românicas e o fator idade.
Construções aspectuais [andar + gerúndio] e [viver + gerúndio] no português
Authors: Ferreira Ana Clara Teixeira , Coelho Sueli Maria
Published: May 2021

Este trabalho elegeu como objeto de estudo duas construções aspectuais da língua portuguesa: [V1ANDAR+ V2GERÚNDIO]e [V1VIVER+ V2GERÚNDIO]. A partir de uma análise quantitativa equalitativa de 542 dados coletados no banco de dados do Corpus do Português (https://www.corpusdoportugues.org/), num recorte sincrônico que contemplou três séculos (XVIII, XIX e XX), avaliou-se a hipótese de que tais construções seriam variantes linguísticas. Os resultados acusaram que, a despeito de ambas as construções evocarem a noção de iteração, elas não são variantes linguísticas. Constatou-se que a construção cujo auxiliar é o verbo VIVER denota uma noção aspectual cujo limite do tempo interno é desconhecido, enquanto a construção que tem ANDAR como verbo auxiliar traduz uma noção aspectual cujo limite de tempo e sua duração são conhecidos. Identificou-se, ainda, que as construções introduzidas pelo verbo ANDAR são mais susceptíveis a serem ambíguas do que aquelas introduzidas pelo verbo VIVER.
Nova Gramática do Latim
Authors: Pereira Virgínia
Published: May 2021

Com uma capa de um amarelo-esverdeado suave e apresentação sobriamente clássica do título e do autor, o que faz com que logo apeteça folhear o volume, chegou às livrarias, em 2019, esta nova gramática que é, segundo palavras da contracapa, “uma obra deconsulta e trabalho e, ao mesmo tempo, um livro fascinante sobre a língua latina, a sua literatura e os mistérios da língua que hoje falamos”. A obra é sem dúvida tudo isto. Mas é muito mais. É realmente uma Nova Gramática.
Fuscoporia valenzuelae (Hymenochaetaceae, Basidiomycota), una especie nueva del bosque tropical caducifolio en México
Authors: Raymundo Tania
Published: May 2021

Antecedentes y Objetivos: El género Fuscoporia se caracteriza por basidiomas resupinados a pileados, sistema hifal dimítico con hifas generativas hialinas con cristales incrustados, setas hifales, setas himeniales, basidiosporas subglobosas, elipsoides o (sub)cilíndricas. Presenta distribución cosmopolita y en México se han registrado 16 especies. El objetivo de este trabajo es describir e ilustrar a Fuscoporia valenzuelae como especie nueva para el bosque tropical caducifolio en México.
Métodos: Los especímenes se recolectaron en el bosque tropical caducifolio de las Reservas de la Biosfera Chamela-Cuixmala y Sierra Álamos-Río Cuchujaqui. Se registraron los datos de campo y las características morfológicas de acuerdo con las técnicas tradicionales en la micología. Los especímenes se encuentran depositados en el herbario ENCB de la Escuela Nacional de Ciencias Biológicas del Instituto Politécnico Nacional.
Resultados clave: Se describe a Fuscoporia valenzuelae, una especie nueva que se caracteriza por basidiomas resupinados grandes de hasta 1.5 m de longitud, himenóforo con poros angulares a irregulares de 1-2 por mm, setas hifales y setas himeniales presentes; basidiosporas elipsoides. Crece sobre Astronium graveolens, causando pudrición blanca.
Conclusiones: Fuscoporia con 17 especies es el taxón mejor representado de Hymenochaetaceae en México. Fuscoporia valenzuelae se distribuye en el bosque tropical caducifolio de la Planicie Costera del Pacífico.