bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of COVID-19 on adolescents’ mental health: a systematic review
Authors: Octavius Gilbert Sterling , Silviani Felicia Rusdi , Lesmandjaja Alicya , Angelina  , Juliansen Andry
Published: December 2020

Background

The impact of COVID-19 towards psychology and mental health is anticipated to be significant and may affect the population disproportionately, especially adolescent as the vulnerable category. We aimed to analyze the impact of COVID-19 towards adolescents’ mental health.

Main body

A systematic search was conducted from Cochrane, Google Scholar, Scielo, and PubMed. Inclusion criteria included all types of studies which observed the effect of COVID-19 and its related causes, such as lockdown, on adolescents’ mental health. All studies were assessed for its level of evidence according to Oxford 2011 criteria and Newcastle Ottawa Scale (NOS). Three studies (Seçer and Ulaş, Int J Ment Health Addict: 1–14, 2020; Zhou et al., Eur Child Adolesc Psychiatry 29:749–58, 2020; Qu et al., Lancet: 1–17, 2020) showed that COVID-19 was a risk factor for mental health problems in adolescents while Oosterhoff et al. (J Adolesc Health 67: 179–185, 2020) showed that adolescents who preferred to stay at home during this pandemic reported less anxiety and depressive symptoms

Conclusion

COVID-19 has been found to be associated with mental health changes in adolescents which meant management of COVID-19 should also focus on mental health as well.
Προς μια ολιστική αντιμετώπιση της διαφοροποιημένης παιδαγωγικής: Αντιλήψεις και πρακτικές εκπαιδευτικών παιδιών προσχολικής ηλικίας
Authors: Σφυρόερα Μαρία
Published: December 2020

Στο πρώτο μέρος του παρόντος κειμένου επιδιώκουμε: α) να επαναπροσδιορίσουμε, με βάση τη θεωρία, τη διαφοροποιημένη παιδαγωγική, εντάσσοντάς την σε μια ολιστική αντίληψη για την εκπαιδευτική διαδικασία και β) να διερευνήσουμε τις προϋποθέσεις υιοθέτησης διαφοροποιημένων προσεγγίσεων από τους εκπαιδευτικούς μέσα από την ανασκόπηση σχετικών ερευνών που μελετούν τις αντιλήψεις των εκπαιδευτικών για τη διαφοροποίηση, όσο και ερευνών που μελετούν απόπειρες εκπαίδευσης εκπαιδευτικών στην κατεύθυνση της διαφοροποιημένης παιδαγωγικής, τα όρια και τις δυσκολίες τους. Στο δεύτερο μέρος,  αξιοποιώντας τη θεωρία, εστιάζουμε στην προσχολική εκπαίδευση επιχειρώντας: α) να αναλύσουμε τις αντιλήψεις νηπιαγωγών και τις δηλωθείσες πρακτικές τους σε σχέση με τη διαφοροποιημένη παιδαγωγική στο ελληνικό νηπιαγωγείο, αντλώντας δεδομένα από 100 ερωτηματολόγια και β) να παρουσιάσουμε τις αντιλήψεις, τις πρακτικές και τους προβληματισμούς, 9 νηπιαγωγών στην προσπάθειά τους να λειτουργήσουν με βάση τις αρχές της διαφοροποιημένης παιδαγωγικής στην τάξη τους. Τα αποτελέσματα αναδεικνύουν ότι, αν και η διαφοροποιημένη παιδαγωγική κατακτά όλο και περισσότερο έδαφος στον λόγο των εκπαιδευτικών παιδιών προσχολικής ηλικίας που αναγνωρίζουν την αξία της για τη νοηματοδότηση της εκπαιδευτικής διαδικασίας και την παροχή ευκαιριών σε όλους τους  μαθητές, ως έννοια παραμένει ασαφής και συνοδεύεται από αρκετές «παρανοήσεις» & αντιφάσεις. Προκειμένου να αξιοποιηθεί ενταγμένη σε μια ολιστική αντίληψη,  απαιτείται  η υιοθέτηση μιας αναστοχαστικής πρακτικής, ρήξεις με τις βιωμένες εκπαιδευτικές εμπειρίες, μακροχρόνιες διαδικασίες επιμόρφωσης και δημιουργία κοινοτήτων πρακτικής.
Psychological and Pedagogical Features of Visualization of Educational Information or "Lessons" of Cartography
Authors: Komissarova Tatyana , Barinova I.
Published: December 2020

The article is devoted to the cartographic teaching method, its psychological and pedagogical features associated with the visualization of spatially distributed information. The method regains its relevance in connection with the spread of "screen" information. The roots of modern infographics, representing any information in a graphical form, lie in the bosom of cartography - the science of displaying the spatial arrangement of things, phenomena using conventional symbols using graphic models - maps. The methodological lessons "lessons" of visualization of educational information are underlined.
643. Diferencias territoriales, sostenibilidad y comunes inmateriales en las costas australes chilenas
Authors: Macías Vázquez Alfredo , Saavedra Gallo Gonzalo
Published: December 2020

Analizamos cómo la gestión de los recursos inmateriales comunes afecta el desarrollo sostenible de las zonas costeras. A partir de una investigación etnográfica, nos concentramos en el estudio de dos producciones marinas, el erizo y el chorito, en cuatro localidades representativas del espacio pesquero-artesanal del sur de Chile. Observamos dos pautas a través de las cuales las élites globales y/o locales cooptan el valor simbólico generado por las comunidades locales con un resultado común: la sobreexplotación de los recursos naturales, la degradación ambiental, el deterioro de las condiciones socioeconómicas de la población y un desempoderamiento de las comunidades en beneficio de las élites. Cuestionamos la retórica neoliberal sobre las ventajas competitivas de las diferencias territoriales en el marco de la globalización y concluimos que estos territorios sufren la depredación de sus recursos comunes (materiales e inmateriales) como resultado de las estrategias rentistas de las élites (burguesías locales y empresas transnacionales).
647. El turismo y su dinámica en la búsqueda de tierra y trabajo baratos: el caso de Los Cabos, Baja California Sur, México
Authors: Escalera-Briceño Alejandro , Palafox-Muñoz Alejandro , Ángeles-Villa Manuel
Published: December 2020

El turismo es una de las actividades más sobresalientes en poco más de sesenta años, su crecimiento ha sido significativo, de tal forma que contribuye favorablemente al crecimiento económico del 85% de los países que reportan datos al respecto, en este sentido los países emergentes recibieron 642 millones de turistas internacionales. Por tal razón, el turismo es un atractivo para las economías periféricas, a fin de enrolarse en los mecanismos desarrollistas para la generación de empleos y la captación de divisas, debido a la vasta cantidad de recursos naturales y culturales, así como de mano de obra barata susceptibles para la implementación de una economía de servicios. Desde la perspectiva de la geografía crítica, el turismo es una actividad más para producir un espacio para la acumulación de capital, de esta manera la producción del espacio turístico requiere de empaquetar de manera gratuita o barata la tierra y la fuerza de trabajo. Estos elementos de bajo costo son una constante histórica para el capital, por lo que el caso de estudio de Los Cabos, permite detallar los procesos de apropiación y capitalización para la ilimitada extracción de ganancias.
Concepções socioambientais sobre a água: reflexões a partir de desenhos
Authors: Silva Ana Cecília da Cruz , Nepomuceno Aline Lima de Oliveira , Machado Wedna de Jesus
Published: December 2020

Objetivou-se com esse estudo analisar a percepção dos alunos sobre a água, através do mapa mental, a fim de sensibilizá-los quanto ao uso sustentável desse recurso e à importância da conservação desse bem. A pesquisa foi desenvolvida em Sergipe, com 53 alunos dos 6os anos e em três fases: exposição dos conteúdos sobre água; elaboração de uma frase e construção do mapa mental; análise e interpretação dos dados. Os alunos abordaram quatro principais temas: poluição, importância e uso consciente, ciclo hidrológico e recurso doméstico. As categorias mais representativas foram: natural sem a presença humana; outras; natural poluído sem a presença humana; e natural e antrópico. A água foi o principal elemento ilustrado, seguido pelo solo, sol, nuvem e peixe. Assim, essa pesquisa revela que a utilização dos mapas mentais colabora para a compreensão da relação dos estudantes com o meio ambiente, permitindo a formação de cidadãos críticos e participativos.
Educação Ambiental, estudo do meio e internalização do conhecimento
Authors: Queiroz Rodrigo José de Góis
Published: December 2020

Neste artigo buscamos pensar a educação ambiental como um processo de ensino e aprendizagem voltado para conscientização social perante a crise ambiental. Tendo como pano de fundo uma crítica da modernidade no qual reconhecemos a mesma como momento histórico de aprofundamento do crescimento econômico e transformação da natureza em valor de troca, propomos uma educação ambiental crítica na perspectiva da construção do conhecimento. Apresentamos um levantamento teórico sobre o processo de internalização do conhecimento, culminando na metodologia pedagógica do estudo do meio. Assim, traçamos uma proposta socioconstrutivista que visa contribuir com a apropriação do conhecimento por parte dos estudantes, no caminho da formação humana de sujeitos ecológicos em luta pela cidadania e justiça ambiental.
Medo odontológico e cárie dentária em crianças: uma revisão crítica da literatura
Authors: Laureano Isla Camilla Carvalho , Farias Lunna , Fernandes Liege Helena Freitas , Cavalcanti Alessandro Leite
Published: December 2020

O medo odontológico é um problema grave que afeta negativamente a saúde bucal. Esta revisão crítica da literatura objetivou identificar os estudos existentes sobre o medo odontológico associado à experiência de cárie dentária em crianças. Tratou-se de estudo bibliográfico realizado nas bases de dados PubMed, Web of Science e Scopus, por meio dos artigos indexados até outubro de 2019. Os termos utilizados foram: “Dental fear”, “Dental anxiety”, “Dental caries” e “Children”. As informações coletadas foram: autor, o ano de publicação, país, desenho do estudo, número amostral, faixa etária (em anos), o instrumento utilizado para avaliar o medo odontológico e os principais resultados. Os dados foram analisados utilizando-se o Microsoft Excel, sendo apresentados descritivamente. Foram obtidos 533 artigos e 28 foram incluídos. A maioria dos estudos foram realizados por pesquisadores brasileiros (32,1%). O número de participantes variou de 99 a 2734 crianças. A idade mais frequente foi de 12 anos (59,3%) e o instrumento mais utilizado foi o questionário Children’s Fear Survey Schedule-Dental Subscale (CFSS-DS) (32,1%), com os respondentes sendo as próprias crianças (82,1%). A prevalência de medo odontológico variou de 5,2% a 66,0%, e os valores de escore médio variaram de 1,50 a 37,0. Os estudos sobre o medo odontológico associado à experiência de cárie dentária em crianças foram realizados em maior número no Brasil, utilizando o questionário CFSS-DS. Existe ampla variabilidade na prevalência e valores de escore médio em diferentes países.
Ileocolonic Histopathological and Microbial Alterations in the Irritable Bowel Syndrome: A Nested Community Case-Control Study
Authors: Talley Nicholas J. , Alexander James L. , Walker Marjorie M. , Jones Michael P. , Hugerth Luisa W. , Engstrand Lars , Agréus Lars , Powell Nicholas , Andreasson Anna
Published: December 2020

INTRODUCTION:

Histopathological alterations in the ileum and colon in irritable bowel syndrome (IBS) are controversial, and normal values are poorly established. We hypothesized that changes in mucosal immune cells characterize IBS and key changes in immune composition are associated with the mucosa-associated microbiota (MaM).

METHODS:

A nested case-control study (48 IBS and 106 controls included) from 745 colonoscopy participants in a random population sample. Intraepithelial lymphocytes (IELs)/100 enterocytes and eosinophils/5 nonoverlapping high-power fields counted; mast cells identified by immunocytochemistry (CD117)/5 high-power fields. Paneth cells quantified per 5 crypts. 16S rRNA gene amplicon sequencing performed on available sigmoid MaM, n = 55 and fecal microbiota, n = 20. Microbiota profiles compared between samples with high and low IEL counts.

RESULTS:

IBS had increased IELs in the terminal ileum (relative risk ratio = 1.70, 95% confidence interval 1.08–2.76, P = 0.022 adjusted for age, sex, and smoking). Cecal IELs were increased in IBS—diarrhea (relative risk ratio = 2.03, 95% confidence interval 1.13–3.63, P = 0.017). No difference was observed in alpha diversity of MaM or fecal microbiota based on IEL count. There was no difference in beta diversity of the MaM according to IEL count in the terminal ileal (TI) (P = 0.079). High TI IEL counts associated with a significant expansion of the genus Blautia (P = 0.024) and unclassified Clostridiales (P = 0.036) in colon MaM.

DISCUSSION:

A modest but significant increase in IELs was observed in IBS vs. controls in a population-based setting. Subtle TI and cecal inflammation may play a pathogenic role in IBS but needs confirmation. Modest but discernible differences in the colonic MaM were seen according to TI IEL count but not IBS status.
Afinal, livro por quê?
Authors: Lampert Letícia
Published: December 2020

Este artigo traz uma reflexão sobre as razões que levam artistas a optar pelo livro como forma de realizar seus projetos, considerando vantagens e desvantagens do formato, além de questões conceituais e pragmáticas que podem estar diretamente relacionadas a este processo. Partindo da experiência pessoal da autora em diferentes publicações, serão abordados processos e motivações por trás de projetos como Escala de Cor do Tempo, Escala de Cor das Coisas, Entre, Manual Prático de Arquitetura,  拆 [chai] e Conhecidos de Vista.
The Effect of Service Quality, Brand Image and Word of Mouth Communication towards the Continuing Study Interest
Authors: an Andri , rdi Supa , an Jumaw , ita Had , Putra Christophorus Indra Wahyu
Published: December 2020

This study aims to determine the extent of the relationship between service quality, brand image and word of mouth communication to the interest in continuing study in management department Faculty of Economics, Universitas Bhayangkara Jakarta Raya. The research methodology used is descriptive quantitative research and multiple linear regression analysis. The data obtained from those management students especially the class of 2018 and 2019, then processed using SPSS version 22 which includes several tests like, Validity Test, Reliability Test, Normality Test, Multicollinearity Test, Heteroscedasticity Test, Multiple Linear Regression Test, Hypothesis Test (t test and F test) and Determination Coefficient Test (r2). Based on the research results obtained that Service Quality (X1) and Brand Image (X2) variables have a negative and insignificant effect on Interest on Continuing Study (Y), but the other variable of Word of Mouth Communication (X3) has a positive and significant effect on Interest on Continuing Study (Y) variable.
Digital Media-based Character Education Model As A Learning Innovation in the Midst of A Corona Pandemic
Authors: Trisiana Anita , Sutikno Arif , Wicaksono Anggit Grahito
Published: December 2020

Online learning or often referred to as online terminology becomes an alternative learning that is currently chosen, during the Corona pandemic. Alternative online learning in this pandemic, can be tangible to develop a character education model that still raises the creativity of media development. Digital media in the form of animation in learning aims to maximize visual effects and provide continuous interaction so that understanding of teaching materials increases. The character education model in Higher Education requires development. The long-term goals to be achieved in this study are as follows: produce a Cartoon Digital Media Based Character Education Model as a learning innovation amid Corona pandemic. Me The method is used da lam this study there was research and development. Data collection techniques used were Data and Source Triangulation, then analyzed using the Interactive Analysis Model. Indicators The success of this research is that the University of Slamet Riyadi Surakarta can support the strengthening of character education models as part of citizens' competencies in the field of Citizenship Education and comprehensive learning outcomes in order to produce graduates who have Strong Character to actively participate in solving the nation's problems responsibly and its implications for the field of Social Humanities and Education. And the novelty of this cartoon digital media-based character education model, provides its own innovation in responding to learning amid the Corona pandemic that is sweeping the world.
Strengthening Policies for Economic and Ecological Sustainability through the Enforcement of Environmental Crimes in Third World
Authors: Ismail Chairuddin
Published: December 2020

This study is motivated to analyze by departing from evidence that the lack of monitoring and evaluation can increase violations and environmental crime. Specifically, this study seeks to analyze the strengthening of environmental policies by highlighting the drivers of environmental crime, and the public policies that need to be formed to reduce environmental crime. By describing from various previous literature, this study found that environmental crime has been transnational with actors from many countries involved. This not only shows the level and geographical extent of crime which is increasingly widespread, but also requires the existence of a legal interface in handling environmental crime. However, an increase in the adequacy and capability of resources in dealing with environmental crimes provided to environmental crime action agencies needs to be strengthened. This is in line with the consideration that limited resources and lack of political impetus result in ineffectiveness in the prevention and handling of environmental crime. Public policies regarding the environmental economy must also actively pressure companies to comply with various environmental regulations and green behavior.
La seguridad alimentaria – un concepto pretencioso
Authors: Pastorino Leonardo Fabio
Published: December 2020

En idioma español, como en italiano y tal vez otros, con la palabra seguridad alimentaria se entienden dos conceptos que en inglés se expresan como food security y food safety. Además, para cada uno de estos conceptos existen distintas definiciones con muy diferentes alcances y relaciones recíprocas. La seguridad alimentaria incluye la disponibilidad, el acceso, la estabilidad, el aspecto nutricional y la inocuidad de los alimentos. En este trabajo se explican cada uno y se desarrollan las dificultades de cada uno para alcanzarlos. También se hace referencia a la defensa alimentaria y a la autosuficiencia alimentaria. Finalmente, se confronta el paradigma de la seguridad alimentaria con el de la soberanía alimentaria.
Group polynomials over rings
Authors: Akishin Aleksandr V.
Published: December 2020

We consider polynomials over rings such that the polynomials represent Latin squares and define a group operation over the ring. We introduce the notion of a group polynomial, describe a number of properties of these polynomials and the groups generated. For the case of residue rings$\mathbb{Z}_{r^n},$where r is a prime number, we give a description of groups specified by polynomials and identify a class of group polynomials that can be used to construct controlled cryptographic transformations.
On the waiting times to repeated hits of cells by particles for the polynomial allocation scheme
Authors: Selivanov Boris I. , Chistyakov Vladimir P.
Published: December 2020

We consider random polynomial allocations of particles over N cells. Let τk, k ≥ 1, be the minimal number of trials when k particles hit the occupied cells. For the case N → ∞ the limit distribution of the random variable $\tau_k/\sqrt{N}$is found. An example of application of τk is given.
Oral sodium phenylbutyrate for hyperammonemia associated with congenital portosystemic shunt: a case report
Authors: Sato Takeshi , Ishii Tomohiro , Kato Mototoshi , Oyanagi Takayuki , Nakatsuka Seishi , Kuroda Tatsuo , Hasegawa Tomonobu
Published: December 2020

Objectives

The efficacy of sodium phenylbutyrate (SPB) for hyperammonemia associated with congenital portosystemic shunt (CPSS) remains unknown. We show the effectiveness of oral SPB.

Case presentation

Our patient had CPSS with severe hypoplasia of extrahepatic portal veins. At 9 months of age, to assess the efficacy of oral SPB, we evaluated the 24 h fluctuations of venous ammonia levels. In the first two days without SPB, ammonia levels were above 80 μmol/L for half a day. On the third and fourth days, administration of oral SPB three times a day decreased ammonia to acceptable levels, except at midnight. On the fifth day, another oral SPB administration at 8 pm decreased ammonia at midnight. Low levels of branched-chain amino acids, as well as coagulation disturbances, were observed without apparent symptoms. At 12 months of age, he showed normal psychomotor development.

Conclusions

Oral SPB may be effective for hyperammonemia associated with CPSS.
Representing Uncertainty in Property Valuation Through a Bayesian Deep Learning Approach
Authors: Lee Changro , Park Keith Key-Ho
Published: December 2020

Although deep learning-based valuation models are spreading throughout the real estate industry following the artificial intelligence boom, property owners and investors continue to doubt the accuracy of the results. In this study, we specify a neural network for predicting house prices. We suggest a standard feed-forward network with two hidden layers, and show that it is sufficiently reasonable to apply its prediction to real-world projects such as property valuation. In addition, we propose a Bayesian neural network for describing uncertainty in house price predictions while providing a means to quantify uncertainty for each prediction. We choose Gangnam-gu, Seoul for the analysis, and predict house prices in the area using both networks. Although the Bayesian neural network did not perform better than the conventional network, it could provide a tool to measure the uncertainty inherent in predicted prices. The findings of this study show that a Bayesian approach can model uncertainty in property valuation, thereby promoting the adoption of deep learning tools in the real estate industry.
GASOMEDIATOR H2S IN THROMBOSIS AND HEMOSTASIS
Authors:   Department of Pediatrics, University of Texas Medical Branch, Galveston, USA, Druzhyna Nadiya
Published: December 2020

This review was aimed to briefly summarize current knowledge of the biological roles of gasomediator H2S in hemostasis and cardiovascular diseases. Since the discovery that mammalian cells are enzymatically producing H2S, this molecule underwent a dramatic metamorphosis from dangerous pollutant to a biologically relevant mediator. As a gasomediator, hydrogen sulfide plays a role of signaling molecule, which is involved in a number of processes in health and disease, including pathogenesis of cardiovascular abnormalities, mainly through modulating different patterns of vasculature functions and thrombotic events. Recently, several studies have provided unequivocal evidence that H2S reduces blood platelet reactivity by inhibiting different stages of platelet activation (platelet adhesion, secretion and aggregation) and thrombus formation. Moreover, H2S changes the structure and function of fibrinogen and proteins associated with fibrinolysis. Hydrogen sulfide regulates proliferation and apoptosis of vascular smooth muscle cells, thus modulating angiogenesis and vessel function. Undoubtedly, H2S is also involved in a multitude of other physiological functions. For example, it exhibits anti-inflammatory effects by inhibiting ROS production and increasing expression of antioxidant enzymes. Some studies have demonstrated the role of hydrogen sulfide as a therapeutic agent in various diseases, including cardiovascular pathologies. Further studies are required to evaluate its importance as a regulator of cell physiology and associated cardiovascular pathological conditions such as myocardial infarction and stroke.
EXPRESSION OF NUCLEOCAPSID VIRAL PROTEINS IN THE BACTERIAL SYSTEM OF Escherichia coli: THE INFLUENCE OF THE CODON COMPOSITION AND THE UNIFORMITY OF ITS DISTRIBUTION WITHIN GENE
Authors:   State Institution ", Fomina E. G. ,   Republican Scientific and Practical Center for Epidemiology and Microbiology",   , Republic of Belarus, Minsk
Published: December 2020

A heterologous host has got a unique expression ability of each gene. Differences between the synonymous sequences play an important role in regulation of protein expression in organisms from Escherichia coli to human, and many details of this process remain unclear. The work was aimed to study the composition of codons, its distribution over the sequence and the effect of rare codons on the expression of viral nucleocapsid proteins and their fragments in the heterologous system of E.coli. The plasmid vector pJC 40 and the BL 21 (DE 3) E. coli strain were used for protein expression. The codon composition analysis was performed using the online resource (www.biologicscorp.com). 10 recombinant polypeptides were obtained encoding the complete nucleotide sequence of nucleocapsid proteins (West Nile and hepatitis C viruses) and the fragments including antigenic determinants (Lassa virus, Marburg, Ebola, Crimean-Congo hemorrhagic fever (CCHF), Puumaravala, Hantaan, and lymphocytic choriomeningitis (LHM)). Hybrid plasmid DNAs provide efficient production of these proteins in the prokaryotic system with the recombinant protein yield varying by a factor of 8: from 5 to 40 mg per 1 liter of bacterial culture. No correlation was found between the level of protein expression and the frequency of occurrence of rare codons in the cloned sequence: the maximum frequency of occurrence of rare codons per cloned sequence was observed for the West Nile virus (14.6%), the minimum was for the CCHF virus (6.6%), whereas the expression level for these proteins was 30 and 5 mg/L culture, respectively. The codon adaptation index (CAI) values, calculated on the basis of the codon composition in E. coli, for the cloned viral sequences were in the range from 0.50 to 0.58, which corresponded to the average expressed proteins. The analysis of the distribution profiles of CAI in the cloned sequences indicated the absence of clusters of rare codons that could create difficulties in translation. A statistically significant difference between the frequencies of the distribution of amino acids in the cloned sequences and their content in E. coli was observed for the nucleocapsid proteins of the Marburg, Ebola, West Nile, and hepatitis C viruses.
PROSPECTS FOR APPLICATION OF BOVINE PERICARDIAL SCAFFOLD FOR CARDIAL SURGERY
Authors:   State Institution ", Sokol A. A. ,   Scientific - Practical Medical Center of Pediatric Cardiology and Cardiac Surgery of the Ministry of Health of Ukraine",   , Kyiv
Published: December 2020

The aim of the\* study was to estimate the properties of the scaffold obtained by decellularization of bovine pericardium with a 0.1% solution of sodium dodecyl sulfate. The experiment included standard histological, microscopic, molecular genetic, and biomechanical methods. Scaffold was tested in vitro for cytotoxicity and in vivo for biocompatibility. A high degree of removal of cells and their components from bovine pericardium-derived matrix was shown. Biomechanical characteristics of artificial scaffold were the same as those of the native pericardium. With prolonged contact, no cytotoxic effect on human cells was observed. The biointegration of the scaffold in laboratory animals tissues was noted, which confirms the potential possibility of the implant applicationin cardiac surgery.
Optimization of methods for preventing intrauterine fluid accumulation in postmenopausal women
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Benyuk V.A. , Kuzmina A.V. ,   Bogomolets National Medical University, Kyiv, Ukraine, Kovaliuk T.V. ,   Bogomolets National Medical University, Kyiv, Ukraine
Published: December 2020

The article presents the features of the specific composition of the vaginal microflora in postmenopausal women with intrauterine fluid and methods for preventing recurrence of intrauterine fluid accumulation. The objective: is to increase the effectiveness of prevention of intrauterine fluid accumulation in postmenopausal women. Materials and methods. We examined 67 postmenopausal women with intrauterine fluid, who made up two statistically equivalent groups. In the first group, two-stage treatment was performed, including etiotropic treatment and the use of vaginal capsules with promestrin. In group II, only etiotropic treatment was performed. Results. The effectiveness of treatment was evaluated using dynamic ultrasound monitoring of pelvic organs. There was no recurrence of intrauterine fluid accumulation in group I patients according to ultrasound data. In group II patients, 51.7% of cases of recurrent accumulation of intrauterine fluid were detected. Conclusions. The proposed step-by-step treatment with promestrin helps restore and regenerate the vaginal mucosa by restoring the balance of the vaginal microflora and maintaining the physiological pH level of the vaginal contents, which also provides prevention of the accumulation of intrauterine fluid in postmenopausal women. Key words: postmenopausal period, endometrial fluid, promestrin.
The state of lactation in women in labor, depending on marital status
Authors:   Bogomolets National Medical University, Kyiv, Ukraine, Kurochka V.V. , Korolyuk N.P. ,   Bogomolets National Medical University, Kyiv, Ukraine, Beniuk S.V. ,   Bogomolets National Medical University, Kyiv, Ukraine
Published: December 2020

The article presents the results of a study of the state of lactation in single and married women in childbirth. The objective: to assess the quantitative and qualitative composition of breast milk in single women on the background of a comprehensive algorithm of therapeutic and preventive measures during pregnancy and childbirth. Materials and methods. The quantitative and qualitative composition of breast milk was assessed in 50 single women against the backdrop of the proposed complex algorithm (main group I), in 50 single women (main group II) and 50 married women (comparison group) with conventional pregnancy and childbirth. To study the state of lactation, the dynamics reflecting changes in the quantity and quality of breast milk were determined in the dynamics of the postpartum period (1, 3, and 7 days). Results. Assessment of the state of lactation revealed hypogalactia and a decrease in the qualitative composition of breast milk, which was manifested by a decrease in the level of lactose and lactoferrin by 1.6 times, transferrin by 1.4 times, total protein and ceruloplasmin by 2.2 times, casein by 1, 5 times, lipids 2.1 times, vitamin C 1.8 times and E 1.5 times, as well as the content of Ig G 2.1 times, IgA 2.2 times, Ig M 1.9 times in single women. Conclusions. Using the proposed algorithm in single women improved the state of lactation, increased normogalactia by 11%, decreased hypogalactia by 16%, the absence of agalactia, increased total protein content by 15.2%, lipids by 17.3% and normalized concentration of immunoglobulins A, M and G. Key words: single mothers, postpartum period, lactation.
Towards a Poetics of Stutter: Semantic and Syntactic Deconstruction in Saint John of the Cross and Stéphane Mallarmé
Authors: Schmelzer Felix
Published: December 2020

The present paper analyzes semantic and syntactic deconstruction in Saint John of the Cross and Stéphane Mallarmé, which is closely connected to the motif of stutter in both their works. It will be shown that, in each case, this motif describes language’s outlying district, an intermediate space between speech and silence, and an ongoing and simultaneous process of dissolution and manifestation that involves the poetic word on the one hand, and the transcendent signified (God in the case of Saint John, mainly the “Spirit” for Mallarmé) on the other.
Upper Chronological Boundary of Sargatha Culture
Authors:   Institute of History and Archaeology Urals Branch of RAS, Sharapova Svetlana
Published: December 2020

The article deals with the antiquity of Sargat culture of forest-steppe in the Trans-Urals and Western Siberia. The established concepts of chronological framework cover the interval from the 5th century BC to 4th-5th centuries AD. Recent studies, both in the main territory and outside the Sargat area, provide evidences for clarifying the upper chronological boundary of the culture. The bright Late Sarmatian appearance of some Sargat burial complexes allows to consider Late Sarmatian finds of the Southern Urals as a reference; rich material has been accumulated on them, as well as detailed chronology.Late Sargathian monuments are found only in two regions - Tobol and Ishim rivers basins. The proposed correction is based on archaeological material which is external data (relative chronology) towards radiocarbon analysis (absolute chronology). In the archaeological collections of Sargat burials there are no any artifacts, the beginning of the period of existence of which falls on the 3rd century AD. There is no such evidence in the settlements either. Furthermore, judging by the available materials, the number of such complexes is small and the inventory is quite poor. The article gives a detailed analysis of burials from seven kurgan cemeteries located in Tobol and Ishim rivers basins, which might be attributed to the latest group marking the upper chronological boundary. In the second half of the 3rd century AD, the main features of the Sargat culture are fading and blurred, besides, it is absent in most of the forest-steppe territory to the east of the Urals. In conclusion the author suggests that if the assumptions are correct, the disappearance of the bright expressive complexes that defined the image of the Sargat social and cultural system, looks quite sharp. The Sargat monuments of the 4th century AD and later are not found across vast forest-steppe territory.
Role of the Retail Sector in Taiwanese Economy
Authors:   Budapest Business School – University of Applied Sciences, Kozák Tamás , Király Éva ,   Budapest Business School – University of Applied Sciences, Nagy Henrietta ,   Budapest Business School – University of Applied Sciences, Neszmélyi György ,   Budapest Business School – University of Applied Sciences
Published: December 2020

The government-guided establishment and incubation of the retail sector in Taiwan has achieved striking success and generated high consumption. This success was even more striking because when the increase of consumption began, the country had not enough retail shopping centers and it was to accept some foreign retail investments. Originally there were no Taiwanese retail firms with deep technological roots and managerial skills. Yet government decision-makers recognized the challenges of upgrading the nation’s economy basing and formulating a strategy that entailed the creation of high-level economic growth which serve as vehicles to stimulate the consumption. Beyond a comprehensive review on Taiwan’s retail sector, the main objective is to analyse the role and the influence of the sector in the Taiwanese macroeconomy. The first issue is getting a picture in Asia (special in Asia – Pacific region) of retail trends. To examine this issue, the authors have done some comparisons between Asia and Europe and apart from the obvious similarities, number of significant differences have been found. The research objective is to provide an effective introduction to the business context of consumption in Taiwan.
Young Generation of Kalmykia: Social Well-Being and Economic Stability (Based on Results of Survey-2019)
Authors:   Kalmyk Scientific Center of the Russian Academy of Sciences, Namrueva Lyudmila
Published: December 2020

The article is devoted to the study of the youth, an important active social group. It represents a quarter of the population and manifests itself in all spheres of life of the republic. One of the factors that encourage the sociological diagnostics of the state of the youth is the emergence of new social and economic threats, development of crisis phenomena in regions with complex ethnic and religious composition, which includes the Kalmyk Republic. Young people tend to participate in processes that are risky and destructive. The article analyzes the individual results of a sociological study conducted in 2019 within the framework of a grant from B. B. Gorodovikov Kalmyk State University supported by the Russian Foundation for Basic Research (N.L. Kurepin). The study allowed us determining not only the problematic aspects of this age group (economic instability, social inequality, etc.), but also the positive aspects that allow us identifying its productive opportunities for updating social relations and economic processes in the region. Our analysis shows that the Republic of Kalmykia is economically protected, as its economy is able to ensure the stability of the economic situation of an individual, provide opportunities for social and economic stability of the regional community, and guarantee protection from various types of threats and losses. The obtained data allows us to state that, despite the unresolved social problems (business, leisure during vacations, holidays, environmental situation in the region, opportunity to express political views), the life of the young population of the republic is stable and sustainable. The majority of the study group has confidence and a positive attitude towards the future, which depends on both their psychological and emotional state and the economic situation in the Kalmyk Republic.
Digitalization of Agro-Industrial Complex: Results, Problems, Directions of Development
Authors:   Volgograd State University, Shkarupa Ekaterina
Published: December 2020

New large-scale agricultural development plans are associated with digitalization, which has become a global trend that sets a new paradigm for the development of Russian economy. The need to develop this study area predetermined the relevance and significance of the implementation of the departmental project “Digital Agriculture.” The article presents the directions of the transformation of agriculture in the conditions of digitalization and systematizes the results of the ongoing questionnaire on this issue. This fact became the basis for the identification of barriers in the industry and points of its development in this context. The paper analyses the existing digital technologies for agriculture. Special attention is paid to accurate agriculture and robotization, the advantages and effects of using them for agricultural production are shown. The study presents the results of a survey in the regions of Russia on the possibilities of using some elements of precision agriculture in the Southern Federal District. The coronavirus pandemic has accelerated the adoption and application of digital technologies. The symbiosis of the digital ecosystem of JSC “Rosselkhozbank” and the leading developer and integrator of digital solutions for the agro-industrial complex APK “IntTerra” created the conditions for appropriate activities for agribusiness through remote technologies. The study states urgent problems of the development and implementation of digital economy in agriculture: a low level of digital infrastructure development in the countryside, a rather low level of staffing, insufficient or complete lack of financial resources in the vast majority of agricultural producers for the introduction of technologies, lack or inefficiency of regional and municipal programs for agribusiness support that introduce digital technologies. The challenges that IT developers face are shown in this article. Priority areas of improvement of policy dealing with agro-industrial complex digitalization are suggested.
Determinants of City Growth in Russia
Authors:   Belgorod State National Research University, Manaeva Inna , Kanishcheva Alexandra ,   Belgorod State National Research University, Tkacheva Anna ,   Belgorod State National Research University
Published: December 2020

Today in Russia there are 1120 cities that are located in the territories with varying degrees of concentration. In the federal districts and regions of the Russian Federation, there is a wide disparity not only in the size of cities, but also in their growth rates. At a decrease in the population in small cities, there is an increase in big towns and cities with more than one million inhabitants. This trend shows the “attraction” of the population from regions into capital cities. The aim of the article is to assess the effects of factors that can influence the growth of a city in the Russian Federation. The scientific novelty of the research consists in the analysis of the influence of external (infrastructure, security) and internal (economic, social, infrastructure, human capital, environmental situation) factors on the growth of cities. The paper presents a system of factor indicators of urban growth. Cities of different sizes have different levels of life standard, and therefore author’s methodology was tested in terms of urban sizes: towns, medium-sized cities, large cities, million-plus cities. The significant factors in the growth of millionplus cities in the Russian Federation are the initial population size and average monthly wages. The growth in the population of large cities is negatively affected by the spatial concentration of industrial enterprises. A high level of average monthly wages contributes to an increase in the population of this type of cities. A significant positive impact on the growth of large cities depends on the concentration of mining industry, volume of investments in fixed assets, number of doctors. The concentration of mining industrial production has a positive effect on the basic growth rate of medium-sized cities. The concentration of manufacturing and the volume of investment in fixed assets have a significant positive effect on the growth of small towns. The practical significance of the obtained results consists in the possibility of creation of a methodological toolkit for the assessment of urban systems of the region, which can become the basis for the development of an algorithm for the strategic planning of the spatial development of cities in the Russian Federation.
Spatial Development of Socially Oriented Non-Profit Organizations in the Urals and South of Russia
Authors:   Ural State University of Economics, Dvoryadkina Elena , Prostova Dina ,   Ural State University of Economics, Dzhalilov Elvin ,   Ural State University of Economics
Published: December 2020

The processes of spatial development of different regions are characterized by different features due to regional specificity, which is also formed under the influence of the structure of regional economy. One of its components is socially oriented non-profit organizations (SONPO). The purpose of the research is to conduct a comparative empirical study of the spatial development of SONPO’s in regions of the Urals and Southern Russia, to identify common trends in their spatial development. The research methodology is based on the theory of spatial economy, in particular on the provisions of the territorial and resource approaches to the study of economic area. The research methods are based on the use and interpretation of basic indicators of the economic area abundance. The zone under analysis is the Ural macro-region (within the economic district) and the South of Russia (within the Southern Federal District). As a result of the research, trends in the spatial development of SONPO’s in the economic area of the Urals and the South of Russia were revealed on the basis of parameters of the dynamics of the number of SONPO’s, as well as the satisfaction of demand from SONPO’s services. The conclusion about the importance of the spatial factor of SONPO’s development was made. It was noted that the directions of the impact strengthening of SONPO’s on the regional spatial development may be specific measures and activities written in regional programs to support their development, such as increase of the number of SONPO’s, implementation of socially significant projects, a set of measures helping to overcome the existing barriers and restrictions in the activities of SONPO’s, as well as the intensification of the implementation of municipal programs to support SONPO’s. The results of the research can be used to control the status and effectiveness of SONPO’s activities in the regions, as well as to specify the spatial development policy.
Tecnología y ciencia en la Orinoquia y la Amazonia
Authors:   Universidad Cooperativa de Colombia, Barajas Pardo Diana Patricia , Cárdenas García Darío ,   Universidad Cooperativa de Colombia, Costanzo Simon ,   Universidad de Maryland, Delreal Cáceres German ,   Universidad Francisco de Paula Santander, Freeman Sarah , Fries Alexandra ,   Universidad de Maryland, Granja Salcedo Yury Tatiana ,   Corporación Colombiana de Investigación Agropecuaria: San Roque, Naranjo Luis Germán ,   WWF Colombia, Pérez Gutierrez Norton ,   Universidad Cooperativa de Colombia, Rodríguez Darabos Emma Isabel , Suárez Cesar Freddy ,   WWF Colombia, Thieme Michele ,   WWF US, Usma Jose Saulo ,   WWF Colombia, Vizcaíno Milcíades
Published: December 2020

La colección interdisciplinaria Estudios de la Orinoquia y la Amazonia busca generar conocimiento, fomentar la discusión académica y asumir alternativas de solución a problemas regionales en la Orinoquia y la Amazonia. Si la Orinoquia y la Amazonia son territorios especiales por su abandono histórico y ellos constituyen una región única, deben tener un tratamiento especial que facilite su desarrollo y promueva el acceso al conocimiento científico y a los bienes producidos en el mundo desarrollado con el respeto a las poblaciones ancestrales y a las culturas regionales. En este primer volumen se encuentran trabajos relacionados con la medicina veterinaria y la investigación en salud en esta región. Las temáticas son variadas y deben ser asumidas desde una apertura teórica, metodológica y procedimental para alcanzar la comprensión del fenómeno en sus dimensiones y en sus contextos.
Familias en la modernidad: una mirada desde Villavicencio
Authors:   Universidad Cooperativa de Colombia, Vizcaíno Milcíades
Published: December 2020

El objeto de estudio de este libro son las familias analizadas desde Villavicencio que es la ciudad colombiana, capital del Meta. Esta ciudad, fundada en 1840, tuvo su mayor desarrollo en la segunda mitad del siglo xx como resultado de migraciones de diversas regiones del país. El mestizaje familiar es un fenómeno que es estudiado a través de tres generaciones desde la década de 1950 hasta la segunda del siglo xxi. Los cambios internos de la estructura familiar, su diversificación, el auge y decaimiento del patriarcalismo, la asimilación de valores modernos llegaron con los medios masivos, la radio y la televisión, y se impulsaron con las nuevas tecnologías. Estos fenómenos dan visibilidad a las transformaciones de las familias que son similares a procesos que se encuentran en otros contextos nacionales e internacionales. La introducción plantea la tesis central y los procedimientos utilizados en su demostración en los seis capítulos del libro.