bluuebunny/crossref_metadata_2025 huggingface dataset:
Nitrogen Mineralization in Texturally Contrasting Soils Subjected to Different Organic Amendments under Semi-Arid Climates
Authors: Javeed Hafiz Muhammad Rashad , Ali Mazhar , Kanwal Nitasha , Ahmad Iftikhar , Jamal Aftab , Qamar Rafi , Zakir Ali , Andaleeb Hina , Jabeen Raheela , Radicetti Emanuele , Mancinelli Roberto
Published: May 2023

Nitrogen (N) is the prime essential nutrient for agricultural productivity, and its deficiency is overcome through the application of fertilizers. However, the rate of N mineralization from organic N sources is an important process to be monitored for efficient N use and sustainable agricultural management. Laboratory incubation studies were conducted for a period of 150 days to measure N mineralization (Nmin) from different organic amendments (OA) in texturally contrasting soils collected at three locations: SL1 (Bahawalpur, sandy loam), SL2 (Bahawalnagar, sandy loam), and SL3 (Rahim Yar Khan, sandy clay loam). A second study was also carried out for 25 days to monitor pH dynamics and ammonia volatilization from the same three OA-treated soils. The results showed that there was no significant difference in net Nmin between the soils for poultry manure (PMO) and feather meal (FMO), even if there was a substantial Nmin observed for PMC + FMO followed by poultry manure compost (PMC) at SL2 and SL3 soils. This might have happened due to higher microbial biomass carbon (257), nitrogen (61), fungal colonization (88 cfu g−1 soil) and enzyme activity (79) in SL3 soil receiving PMC + FMO after 150 days of incubation. However, the first-order kinetic model (R2 = 0.86–0.95) better explained the Nmin in all three soils amended with OA (PMC + FMO). The soil pH had more pronounced effects on Nmin in all three soils. A non-significant amount of ammonia volatilization was recorded regardless of the initial pH, buffering capacity, and texture variability of the soils. Further study on the particle size of OA and soil pH is warranted to determine the actual effect of OA on Nmin.
Zoning and Management of Ecological Restoration from the Perspective of Ecosystem Service Supply and Demand: A Case Study of Yuzhong County in Longzhong Loess Hilly Region, China
Authors: Li Ziyan , Ma Libang , Chen Xianfei , Wang Xiang , Bai Jing
Published: May 2023

The loess hilly region is a typical ecologically fragile and sensitive area. It is of great significance when measuring the balance between supply and demand of ecosystem services and clarify the relationship between supply and demand of ecosystem services for scientific ecological restoration zoning and realizing regional ecological security and social and economic sustainable development. We take Yuzhong County in the loess hilly region of Longzhong, China as an example; by constructing the matching and coordinating relationship between ecosystem service supply and demand and following the idea of “problem diagnosis—strategic orientation—key optimization”, this paper delimits the ecological restoration zones and proposes corresponding governance strategies. The results show that: (1) The supply and demand of ecosystem services were mainly at a low and medium level, with significant spatial heterogeneity. Overall, the spatial pattern of ecosystem services showed high supply and low demand in the southwest mountainous areas and showed low supply and high demand in the urban gully areas of Yuzhong. (2) There were four types of spatial matching of ecosystem service supply and demand: HH type, LH type, LL type, and HL type. The local spatial autocorrelation of supply and demand was dominated by high-low or low-high spatial misadjustment. The average degree of coordination between supply and demand of ecosystem services was 0.629, indicating that supply and demand were basically coordinated. (3) The ecological restoration zones in Yuzhong County can be divided into six categories: the ecological core protection area, ecological potential restoration area, key ecological restoration area, soil and water conservation restoration area, ecological agriculture development area, and ecological innovation promotion area. The results of this study can provide ideas for the refined management and targeted restoration practice of regional ecosystem services. It provides a strong guarantee for ecosystem management and decision-making in the loess hilly region.
Research on Land Use Pattern and Ecological Risk of Lanzhou–Xining Urban Agglomeration from the Perspective of Terrain Gradient
Authors: Wang Ziyang , Shi Peiji , Shi Jing , Zhang Xuebin , Yao Litang
Published: May 2023

At the intersection of the Qinghai–Tibet Plateau and Loess Plateau, topographic factors often profoundly affect the evolution of the regional land use pattern and ecological risk. This paper takes the Lanzhou–Xining urban agglomeration as the research area, divides the topographic gradient based on the topographic index, analyzes the characteristics of the land use pattern using the land use transfer matrix model, dynamic attitude and state degree model, and analyzes the influence of topographic factors on the land use pattern using the distribution model. At the same time, an ecological risk evaluation index system is constructed, the spatial principal component method is used to evaluate the ecological risk, and the influence of topography on the regional ecological risk is discussed. The results show that from 1990 to 2020, the area of construction land in the study area increased by 1045.807 km2 and the area of ecological land increased by 587.41 km2, with the most significant changes occurring in the attitude and state of construction land and unused land. It is found that cultivated land, water area and construction land are dominant in low terrain, while woodland, grassland and unused land are mainly distributed in middle and high terrain. During the study period, the ecological risk in the midwest and southeast of the Lanzhou–Xining urban agglomeration decreased, while the ecological risk in the northeast increased first and then decreased, although generally there was an increasing trend. Moran’s I varied from 0.942 to 0.955 from 1990 to 2020, indicating that the ecological risk index in the study area was highly positively correlated in space, while the spatial aggregation effect of the ecological risk was obvious. Low and moderately low risk areas are mainly distributed in high terrain, while high and moderately high risk areas are dominant in low terrain. The research results of this paper can make a lot of sense for ecological protection, land resource utilization and sustainable development of the Lanzhou–Xining urban agglomeration.
Environmental Risks of Water Resources in the Belarusian Polesie
Authors: Kirvel Ivan , Volchak Alexander , Parfomuk Sergey , Kirvel Pavel
Published: May 2023

The article is devoted to the problems of water resources in Belarusian Polesie. Surface water resources analysis was carried out for the different types of runoffs. There was a significant decrease in maximum spring runoff and a decrease in the average annual runoff. A statistically significant increase in the minimum winter runoff is observed for the rivers of the Pripyat River basin. For the minimum summer–autumn runoff, there was no unambiguous trend in the runoff change. Quality of natural waters analysis included investigation of the annual concentrations of priority substances in the water of some rivers in Polesie for dissolved oxygen, phosphates, nitrogen, petroleum products, copper, zinc, etc. In general, there have been trends toward a pollution decrease in the Polesie Rivers. The possible consequences of changes in river runoff due to climate change are considered. The priority tasks of research on solving the Polesie water problems are outlined.
Path Planning and Navigation of Miniature Serpentine Robot for Bronchoscopy Application
Authors: Kuan Cheng-Peng , Huang Shu , Wu Hao-Yan , Wang An-Peng , Wu Chien-Yu
Published: May 2023

The miniature serpentine robot can be applied to NOTES (Natural Orifice Transluminal Endoscopic Surgery). In this paper, a bronchoscopy application is addressed. This paper describes the basic mechanical design and control scheme of this miniature serpentine robotic bronchoscopy. In addition, off-line backward path planning and real-time and in situ forward navigation in this miniature serpentine robot are discussed. The proposed backward-path-planning algorithm utilizes the 3D model of a bronchial tree constructed from the synthetization of medical images such as images from CT (Computed Tomography), MRI (Magnetic Resonance Imaging), or X-ray, to define a series of nodes/events backward from the destination, for example, the lesion, to the original starting point, for example, the oral cavity. Accordingly, forward navigation is designed to make sure this series of nodes/events shall be passed/occur from the origin to the destination. This combination of backward-path planning and forward navigation does not require accurate positioning information of the tip of the miniature serpentine robot, which is where the CMOS bronchoscope is located. Collaboratively, a virtual force is introduced to maintain the tip of the miniature serpentine robot at the center of the bronchi. Results show that this method of path planning and navigation of the miniature serpentine robot for bronchoscopy applications works.
Concurrently Fabricating Precision Meso- and Microscale Cross-Scale Arrayed Metal Features and Components by Using Wire-Anode Scanning Electroforming Technique
Authors: Li Shicheng , Ming Pingmei , Zhang Junzhong , Zhang Yunyan , Yan Liang
Published: May 2023

In order to improve the thickness uniformity of the electroformed metal layer and components, a new electroforming technique is proposed—wire-anode scanning electroforming (WAS-EF). WAS-EF uses an ultrafine inert anode so that the interelectrode voltage/current is superimposed upon a very narrow ribbon-shaped area at the cathode, thus ensuring better localization of the electric field. The anode of WAS-EF is in constant motion, which reduces the effect of the current edge effect. The stirring paddle of WAS-EF can affect the fluid flow in the microstructure, and improve the mass transfer effect inside the structure. The simulation results show that, when the depth-to-width ratio decreases from 1 to 0.23, the depth of fluid flow in the microstructure can increase from 30% to 100%. Experimental results show that. Compared with the traditional electroforming method, the single metal feature and arrayed metal components prepared by WAS-EF are respectively improved by 15.5% and 11.4%.
A Single-Side Micromachined MPa-Scale High-Temperature Pressure Sensor
Authors: Li Peng , Li Wei , Chen Changnan , Wu Sheng , Pan Pichao , Sun Ke , Liu Min , Wang Jiachou , Li Xinxin
Published: May 2023

This paper proposes a piezoresistive high-temperature absolute pressure sensor based on (100)/(111) hybrid SOI (silicon-on-insulator) silicon wafers, where the active layer is (100) silicon and the handle layer is (111) silicon. The 1.5 MPa ranged sensor chips are designed with the size as tiny as 0.5 × 0.5 mm, and the chips are fabricated only from the front side of the wafer for simple, high-yield and low-cost batch production. Herein, the (100) active layer is specifically used to form high-performance piezoresistors for high-temperature pressure sensing, while the (111) handle layer is used to single-side construct the pressure-sensing diaphragm and the pressure-reference cavity beneath the diaphragm. Benefitting from front-sided shallow dry etching and self-stop lateral wet etching inside the (111)-silicon substrate, the thickness of the pressure-sensing diaphragm is uniform and controllable, and the pressure-reference cavity is embedded into the handle layer of (111) silicon. Without the conventionally used double-sided etching, wafer bonding and cavity-SOI manufacturing, a very small sensor chip size of 0.5 × 0.5 mm is achieved. The measured performance of the 1.5 MPa ranged pressure sensor exhibits a full-scale output of approximately 59.55 mV/1500 kPa/3.3 VDC in room temperature and a high overall accuracy (combined with hysteresis, non-linearity and repeatability) of 0.17%FS within the temperature range of −55 °C to 350 °C. In addition, the thermal hysteresis is also evaluated as approximately 0.15%FS at 350 °C. The tiny-sized high temperature pressure sensors are promising in various industrial automatic control applications and wind tunnel testing systems.
The Performance of the Two-Seeded GdBCO Superconductor Bulk with the Buffer by the Modified TSMG Method
Authors: Zhang Yufeng , Li Chunyan , Lou Ziwei , Zhang Penghe , Zhang Yan , Shen Shuangyuan , Ruan Guanjie , Zhang Jiaying
Published: May 2023

The multiseeding technique is a method to grow large-sized REBa2Cu3O7−δ (REBCO, where RE is a rare earth element) high temperature superconducting bulks. However, due to the existence of grain boundaries between seed crystals, the superconducting properties of bulks are not always better than those of single grain bulks. In order to improve the superconducting properties caused by grain boundaries, we introduced buffer layers with a diameter of 6 mm in the growth of GdBCO bulks. Using the modified top-seeded melt texture growth method (TSMG), that is, YBa2Cu3O7−δ (Y123) as the liquid phase source, two GdBCO superconducting bulks with buffer layers with a diameter of 25 mm and a thickness of 12 mm were successfully prepared. The seed crystal arrangement of two GdBCO bulks with a distance of 12 mm were (100/100) and (110/110), respectively. The trapped field of the GdBCO superconductor bulks exhibited two peaks. The maximum peaks of superconductor bulk SA (100/100) were 0.30 T and 0.23 T, and the maximum peaks of superconductor bulk SB (110/110) were 0.35 T and 0.29 T. The critical transition temperature remained between 94 K and 96 K, with superior superconducting properties. The maximum JC, self-field of SA appeared in specimen b5, which was 4.5 × 104 A/cm2. Compared with SA, the JC value of SB had obvious advantages in a low magnetic field, medium magnetic field and high magnetic field. The maximum JC, self-field value appeared in specimen b2, which was 4.65 × 104 A/cm2. At the same time, it showed an obvious second peak effect, which was attributed to Gd/Ba substitution. Liquid phase source Y123 increased the concentration of the Gd solute dissolved from Gd211 particles, reduced the size of Gd211 particles and optimized JC. For SA and SB under the joint action of the buffer and the Y123 liquid source, except for the contribution of Gd211 particles to be the magnetic flux pinning center with the improvement of JC, the pores also played a positive role in improving the local JC. More residual melts and impurity phases were observed in SA than in SB, which had a negative impact on the superconducting properties. Thus, SB exhibited a better trapped field and JC.
Isolation of a Multidrug-Resistant vanA-Positive Enterococcus faecium Strain from a Canine Clinical Sample in Greece
Authors: Lysitsas Marios , Triantafillou Eleftherios , Tzavaras Ioannis , Karamichali Panagiota , Agathaggelidis Kiriakos , Tsokana Constantina N. , Dushku Esmeralda , Katsiaflaka Anna , Billinis Charalambos , Valiakos George
Published: May 2023

An Enterococcus faecium strain was obtained from a paraprostatic cyst of a 17-year-old dog in Greece. Antibiotic susceptibility testing (AST) was accomplished by disc diffusion and MIC methods, and the isolate demonstrated a multidrug-resistant (MDR) phenotype against a great variety of antibiotics, such as β-Lactams, Quinolones, Macrolides, Tetracyclines, Rifampin, Nitrofurantoin, and surprisingly, Glycopeptides, Fosfomycin and Gentamicin (high-level). Molecular screening for Vancomycin resistance genes was carried out, and a vanA gene cluster was identified. To our knowledge, this is the first report of a vanA-positive E. faecium strain isolated from a companion animal in Greece. Importantly, this strain was related with the presence of paraprostatic cysts, a pathological condition requiring treatment. The presence of a highly resistant isolate in a canine clinical sample and the consequent need for treatment constitutes a new challenge for veterinarians due to the lack of available treatment options. Our findings indicate the occurrence of respective bacteria in companion animals, which could act as a reservoir of epidemic MDR strains or relevant mobile genetic elements (MGE) in the community, constituting a threat for public health.
Pharmacological Effects of Lactobacillus casei ATCC 7469 Fermented Soybean and Green Microalgae, Chlorella vulgaris, on Diabetic Rats
Authors: Abdella Asmaa , Abou-Elazm Fatma I. , El-Far Shaymaa Wagdy
Published: May 2023

Type 2 diabetes mellitus (T2DM) is a complex, multifactorial metabolic disorder mainly characterized by chronic hyperglycemia. It has become a significant, serious disease worldwide, presenting a huge risk to human life and health. This study aimed to investigate the hypoglycemic effect of Lactobacillus casei ATCC 7469 fermented soy flour extract and Chlorella vulgaris extract on Sprague-Dawley rats with T2DM induced by low-dose streptozotocin administration (STZ) compared to pioglitazone as a reference drug. Treatment with Lactobacillus casei ATCC 7469 fermented soy flour and Chlorella vulgaris resulted in a significant improvement in body weight, glucose tolerance, blood glucose level, and insulin resistance (p < 0.05). It also resulted in a significant decrease in total cholesterol (T.C), triglycerides (T.G), low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL) (p < 0.05) and a significant increase in high-density lipoprotein (HDL) (p < 0.05). It also resulted in the improvement of liver oxidative biomarkers. Moreover, it prevented pancreatic histopathological changes. Lactobacillus casei ATCC 7469 fermented soy flour extract and Chlorella vulgaris extract had hypoglycemic, hypolipidemic, and antioxidant activity similar to pioglitazone.
Convergence of Pro-Stress and Pro-Inflammatory Signaling in the Central Noradrenergic System: Implications for Mood and Anxiety Disorders
Authors: Reyes Arthur Anthony A. , Chandler Daniel J.
Published: May 2023

Mood and anxiety disorders are heterogeneous psychiatric diagnoses affecting millions. While the disease etiology is complex, various risk factors have been identified, such as stress. Stress is a neuroendocrine physiologic response to a stressor that promotes organism survival through adaptive processes and behavior. The central stress response, which drives behavioral and physiological change, is primarily mediated by activating the hypothalamic–pituitary–adrenal (HPA) axis. In addition to its effects on the HPA axis, stress activates the locus coeruleus (LC), a bilateral brainstem nucleus that projects broadly throughout the central nervous system and releases the catecholamine transmitter norepinephrine (NE). The combined activities of the LC–NE system and HPA axis work synergistically to produce timely adaptive physiological and behavioral responses to stress. While advantageous in the short term, chronic stress exposure can lead to HPA axis and LC dysregulation, which are thought to contribute to the etiology of several neuropsychiatric disease states. Notably, recent studies have also implicated neuroinflammation mediated by microglia as a risk factor in mood and anxiety disorders. Despite their combined association with mood and anxiety disorders, the potential links between stress and inflammation, and possible interactions between their respective signaling cascades, have not been well-explored. This brief review aims to summarize how LC is uniquely positioned to respond to both pro-stress and pro-inflammatory cues, and how their convergence in this site may contribute to the development of mood and anxiety disorders.
Semi-Automated Recording of Facial Sensitivity in Rat Demonstrates Antinociceptive Effects of the Anti-CGRP Antibody Fremanezumab
Authors: Benedicter Nicola , Messlinger Karl , Vogler Birgit , Mackenzie Kimberly D. , Stratton Jennifer , Friedrich Nadine , Dux Mária
Published: May 2023

Migraine pain is frequently accompanied by cranial hyperalgesia and allodynia. Calcitonin gene-related peptide (CGRP) is implicated in migraine pathophysiology but its role in facial hypersensitivity is not entirely clear. In this study, we investigated if the anti-CGRP monoclonal antibody fremanezumab, which is therapeutically used in chronic and episodic migraines, can modify facial sensitivity recorded by a semi-automatic system. Rats of both sexes primed to drink from a sweet source had to pass a noxious mechanical or heat barrier to reach the source. Under these experimental conditions, animals of all groups tended to drink longer and more when they had received a subcutaneous injection of 30 mg/kg fremanezumab compared to control animals injected with an isotype control antibody 12–13 days prior to testing, but this was significant only for females. In conclusion, anti-CGRP antibody, fremanezumab, reduces facial sensitivity to noxious mechanical and thermal stimulation for more than one week, especially in female rats. Anti-CGRP antibodies may reduce not only headache but also cranial sensitivity in migraineurs.
Prevalence and Risk Factors Associated with Theileria annulata Infection in Two Bovine Portuguese Autochthonous Breeds
Authors: Valente Diana , Dutra Ana Paula , Carolino Nuno , Gomes Jacinto , Coelho Ana Cláudia , Espadinha Pedro , Pais José , Carolino Inês
Published: May 2023

Tropical Bovine Theileriosis is an important tick-borne disease. This study aims to assess the occurrence of Theileria annulata infection in two indigenous Portuguese cattle breeds. A total of 843 blood samples collected from animals of Alentejana (n = 420) and Mertolenga (n = 423) breeds were analyzed. The detection of Theileria annulata was determined by amplification of a fragment of the merozoite-pyroplasm surface antigen gene with 319 base pairs (bp). The prevalence found (10.8%) is lower than that reported in previous studies (21.3%). A statistically significant difference was found for positivity between breeds (p < 0.05). There is also a higher probability of older animals being positive compared to younger ones (p < 0.05). The region where Mertolenga animals are located is shown to have a significant impact on positivity (p < 0.05). Thus, the development of sustainable T. annulata control strategies and their implementation, adapted to the epidemiological conditions of higher risk, will be extremely important.
Nonwoven Fabrics from Agricultural and Industrial Waste for Acoustic and Thermal Insulation Applications
Authors: Periyasamy Aravin Prince
Published: May 2023

Natural fibers are increasingly being used to make nonwoven fabrics, substituting synthetic materials for environmental and economic reasons. In this study, a series of needle-punched nonwoven fabrics were made by extracting fibers from coffee husks and blending them with a proportion of spinning waste consisting of cotton fibers and another five different natural fibers. This work investigates the coefficient of sound absorption, thermal conductivity, areal density, thickness, and air permeability. Overall, the sound absorption properties of the produced nonwoven fabric depend on the blend proportion and the number of layers. The results from the fabric containing nettle and banana fibers demonstrate a much-improved sound absorption coefficient. These results have been compared with those of commercially available nonwoven fabrics that are manufactured from polyester and polyurethane foam. The thermal conductivities of the fabrics made with nettle and coir were the highest and lowest, respectively. This is because of the fiber linear density, but all in all, fibers extracted from coffee husks show significantly promising potential for scaling up to replace existing synthetic fibers.
The National Cancer Institute’s Co-Clinical Quantitative Imaging Research Resources for Precision Medicine in Preclinical and Clinical Settings
Authors: Zhang Huiming
Published: May 2023

Genetically engineered mouse models (GEMMs) and patient-derived xenograft mouse models (PDXs) can recapitulate important biological features of cancer. They are often part of precision medicine studies in a co-clinical setting, in which therapeutic investigations are conducted in patients and in parallel (or sequentially) in cohorts of GEMMs or PDXs. Employing radiology-based quantitative imaging in these studies allows in vivo assessment of disease response in real time, providing an important opportunity to bridge precision medicine from the bench to the bedside. The Co-Clinical Imaging Research Resource Program (CIRP) of the National Cancer Institute focuses on the optimization of quantitative imaging methods to improve co-clinical trials. The CIRP supports 10 different co-clinical trial projects, spanning diverse tumor types, therapeutic interventions, and imaging modalities. Each CIRP project is tasked to deliver a unique web resource to support the cancer community with the necessary methods and tools to conduct co-clinical quantitative imaging studies. This review provides an update of the CIRP web resources, network consensus, technology advances, and a perspective on the future of the CIRP. The presentations in this special issue of Tomography were contributed by the CIRP working groups, teams, and associate members.
Development of Effective PEDV Vaccine Candidates Based on Viral Culture and Protease Activity
Authors: Kim Dae-Min , Moon Sung-Hyun , Kim Seung-Chai , Cho Ho-Seong , Tark Dongseob
Published: May 2023

Porcine epidemic diarrhea (PED) is a highly contagious disease that has been reported annually in several Asian countries, causing significant economic losses to the swine livestock industry. Although vaccines against the porcine epidemic diarrhea virus (PEDV) are available, their efficacy remains questionable due to limitations such as viral genome mutation and insufficient intestinal mucosal immunity. Therefore, the development of a safe and effective vaccine is necessary. In this study, a virulent Korean strain of PEDV, CKT-7, was isolated from a piglet with severe diarrhea, and six different conditions were employed for serial passage of the strain in a cell culture system to generate effective live attenuated vaccine (LAV) candidates. The characteristics of these strains were analyzed in vitro and in vivo, and the CKT-7 N strain was identified as the most effective vaccine candidate, with a viral titer peak of 8.67 ± 0.29 log10TCID50/mL, and no mortality or diarrhea symptoms were observed in five-day-old piglets. These results indicate that LAV candidates can be generated through serial passage with different culture conditions and provide valuable insights into the development of a highly effective LAV against PEDV.
Effects of Electrochemotherapy on Immunologically Important Modifications in Tumor Cells
Authors: Kesar Ursa , Markelc Bostjan , Jesenko Tanja , Ursic Valentinuzzi Katja , Cemazar Maja , Strojan Primoz , Sersa Gregor
Published: May 2023

Electrochemotherapy (ECT) is a clinically acknowledged method that combines the use of anticancer drugs and electrical pulses. Electrochemotherapy with bleomycin (BLM) can induce immunogenic cell death (ICD) in certain settings. However, whether this is ubiquitous over different cancer types and for other clinically relevant chemotherapeutics used with electrochemotherapy is unknown. Here, we evaluated in vitro in the B16-F10, 4T1 and CT26 murine tumor cell lines, the electrochemotherapy triggered changes in the ICD-associated damage-associated molecular patterns (DAMPs): Calreticulin (CRT), ATP, High Mobility Group Box 1 (HMGB1), and four immunologically important cellular markers: MHCI, MHC II, PD-L1 and CD40. The changes in these markers were investigated in time up to 48 h after ECT. We showed that electrochemotherapy with all three tested chemotherapeutics induced ICD-associated DAMPs, but the induced DAMP signature was cell line and chemotherapeutic concentration specific. Similarly, electrochemotherapy with CDDP, OXA or BLM modified the expression of MHC I, MHC II, PD-L1 and CD40. The potential of electrochemotherapy to change their expression was also cell line and chemotherapeutic concentration specific. Our results thus put the electrochemotherapy with clinically relevant chemotherapeutics CDDP, OXA and BLM on the map of ICD inducing therapies.
Basic Study on Mechanical Vibration Suppression System Using 2-Degree-of-Freedom Vibration Analysis
Authors: Ikeda Keigo , Kamimori Kota , Kobayashi Ikkei , Kuroda Jumpei , Uchino Daigo , Ogawa Kazuki , Endo Ayato , Kato Taro , Liu Xiaojun , Peeie Mohamad Heerwan Bin , Kato Hideaki , Narita Takayoshi
Published: May 2023

Mechanical vibrations adversely affect mechanical components, and in the worst case, lead to serious accidents by breaking themselves. To suppress vibrations, various studies have been conducted on vibration isolation, suppression, and resistance. In addition, technologies to actively suppress vibration have been rapidly developed in recent years, and it has been reported that vibrations can be suppressed with higher performance. However, these studies have been conducted mostly for low-order systems, and few studies have employed control models that consider the complex vibration characteristics of multi-degree-of-freedom (DOF) systems. This study is a basic study that establishes a control model for complex control systems, and the vibration characteristics of a 2-DOF system are calculated using the vibration analysis of a multi-DOF system. Furthermore, the vibration suppression performance of the 2-DOF system is investigated by performing vibration experiments.
Experiências de economia social : mutualismo, filantropia e corporativismo
Authors: Viscardi Cláudia Maria Ribeiro
Published: May 2023

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Escola pública : igualdade e pluralidade no capitalismo contemporâneo
Authors: Rodrigues Rubens Luiz
Published: May 2023

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Kekerasan Seksual: Berkelindan di Antara Norma Hukum dan Agama
Authors: Anshor Maria Ulfah
Published: May 2023

Sexual violence experienced by women with a variety of experiences is at the risk of not being recognized by the public, even by law enforcement officials who are not conscious of a victim’s perspective. This shows that there is a ‘big’ problem related to the public’s perspective on legal norms which makes its implementation conflicting with the constitution which guarantees rights and access to justice for women as citizens. This problem is also supported by an interpretation of religion that is not in favor of victims of sexual violence. This research is carried out to ensure that women who became victims of rape have access to justice in safe abortion services guaranteed by the constitution and religion (Islam). This is the novelty of this research, which is expected to fill in the gaps in a number of previous studies. The research methodology uses a descriptive qualitative approach.
Aspecte ale discursului contemporan din spaţiul social românesc
Authors: SOARE Ovidiu
Published: May 2023

I sought to sketch a certain perspective of the discourse and, thus of the mentalities that troubled and have been troubling our society for the past half-century; our society is divided into two periods, one, a communist period,  focused on a "utopian and bright" future, supported by an intense social control, and the other where we are today, where rumours and uncertainty are the order of the day. We hope that all these quests of our society, which has been in an endemic transition for several hundredyears, will eventually lead to that much-desired stability and credibility, present in any normal society.
Satul Ibăneşti Pădure. O perspectivă sociologică şi noi izvoare documentare
Authors: TODORAN Vasile
Published: May 2023

The present study aims to analyze, through the prism of sociology, the village of Ibăneşti Pădure. This village gave birth to a religious community where the villagers are guided by biblical, patristic and dogmatic rules, enlivened by the traditional spirit of the villagers. The church has been a guide of conscience in the mentality of the people, and the teachings it has promoted have led people to take them and apply them in daily life to generate spiritual values. The fundamental norm for the religious community is the belief in the Supreme Entity (God), which is a producer of norms and which in turn give rise to other and other spiritual values. Every villager, assimilating the norms and putting them into social practice, creates the mystical-spiritual life for the religious community and which culminates with the ethos of the village. The spirit of the village is born when the religious community appropriates the rules to produce spiritual values. These rules are virtual germs that are growing and developing for the religious community.
Esprits formateurs et « renaissance » culturelle dans les provinces roumaines au XIXème siècle
Authors: COSTANDACHE Ana-Elena
Published: May 2023

In the 19th century, the Romanian provinces overcame difficulties at all levels: political, social, cultural. Significant changes were also felt in the processes of reception and assimilation of European values when new aesthetics were integrated into indigenous mentalities according to the artistic, moral end ideological needs of Romanians. As formative minds, the writers wanted at all costs to adapt to the European context; they renounced pattern of ancient writing (neoclassical poetry, for example) and embraced new forms of literary expression. Moreover, by their education made according to the modern European spirit, they gave examples of erudition and education which were grafted on the national culture. Our study offers an incursion into the Romanian cultural space of the 19th century in order to present a faithful image of the cultural “renaissance” in the Romanian provinces of that time.
Family-Mark of Identity and Spirituality of the Turkish Community in Romania
Authors: ABDULA-NAZARE Gülten
Published: May 2023

The family is one of the important institutions that has survived from the past to the present. In this paper I will try to present the structure and features of the Turkish family starting from the pre-Islamic, Islamic-Ottoman period until the modern period. The solid family structure and the order played an extremely important role in the mobility of the Turkish nation in a very wide geography that shaped history. To this end, I will provide brief information about the Turkish family, its importance to society, marriage ceremonies, communication between family members and other relatives, as well as some traditions specific to the Turkish family. The social structure of the family, the basic dynamics and the main driving force of society differ from society to society, from culture to culture as we will see also in the Turkish family. The ancient Turks, whose life and culture was nomadic, therefore, the structure and life of the family were modelled according to the conditions of nomadic life. Family members had to fight together against difficult living conditions. In this situation, children, girls and boys, have been involved in adult roles since an early age. In the old Turkish family, the man is a person with important functions and duties and the woman is the foundation of human society. The Turkish family in Romania can be presented from two perspectives: the Ottoman Turkish family and the modern Turkish family. By presenting the two components we will notice that the impact of modernism or rather of post-modernism is making its mark more and more, leading to the loss of traditional values that are intertwined with the spiritual crisis.
Histoire contemporaine de Croix Rouge d’Izmail sur les pages des médias électroniques ukrainiennes
Authors: MUDRA Anna
Published: May 2023

Dans cet article, dans le cadre de recherches du Cercle scientifique interdisciplinaire interfacultaire universitaire « Histoire de la Croix Rouge d’Izmail » qui mène ses activités en langues étrangères, on fait l'analyse de presse locale de la période de 2010-2017, qui reflète le travail de l'organisation de Croix Rouge d’Izmail, sous la dirigeance de Mme Halyna Semenivna Dimova (Choutko) – la Présidente d’Honneur du Cercle scientifique. On parle de l'analyse des matériaux électroniques des éditions: « City », « Kourier nedeli », « Dounaetz », etc.
Evoluţia resurselor umane în comunităţile marginalizate din Alba Iulia
Authors: BOC Ovidiu-Valentin , TODORAN Vasile
Published: May 2023

The research aims at the evolution of the human resource and the integrated measures to support this resource towards a positive evolution and social reinsertion. The three mixed communities constitute the areas of marginalization, and the investments of the last period aimed precisely at the human resource. That is why the research aims to identify the main changes in the life of these communities from the perspective of human resources and the main metamorphoses that occurred following the implementation of projects.
A Compact SWB Monopole Antenna and FSS for Gain Enhancement
Authors: Khan Imran , Qiu Hongbing , Ur Rahman Saeed , Ullah Habib
Published: May 2023

In this research, a compact super-wideband monopole antenna is introduced. The antenna's electrical dimensions are 0.228λ × 0.144λ × 0.009λ, the λ represents the wavelength of the lowest operating frequency. The suggested antenna achieves a single operating band 10 dB between 2.8 and 40 GHz, a percentage bandwidth of 173.83%, and a BW ratio greater than 10:1. The suggested super wideband antenna has a large BDR of 5432.18 and a maximum gain of 6.6 dB. The antenna features a U-shaped radiating element and a rectangular, chamferedcornered partial ground plane to attain super wideband characteristics. The antenna has been designed to be compact and flat in structure while still providing adequate gain and a broad range of frequencies, which makes it suitable for a variety of uses in contemporary wireless communication. To increase the antenna, gain for ultrawideband applications, an FSS is developed. The FSS has a compact unit cell with physical dimensions of 18 x 18 mm2 . When the FSS is used as a substrate, the antenna reaches a maximum realized gain of 10 dB. Additionally, at UWB frequencies, a gain amendment of up to 4.61 dB is observed.
Task Scheduling Optimization in Cloud Computing by Coronavirus Herd Immunity Optimizer Algorithm
Authors: Y. Hamed Ahmed , Elnahary M. Kh. , El-Sayed Hamdy H.
Published: May 2023

Cloud computing is now dominant in high-performance distributed computing, offering resource polling and ondemand services over the web. So, the task scheduling problem in a cloud computing environment becomes a significant analysis space due to the dynamic demand for user services. The primary goal of scheduling tasks is to allocate tasks to processors to achieve the shortest possible makespan while respecting priority restrictions. In heterogeneous multiprocessor systems, task and schedule assignments significantly impact the system's operation. Therefore, the different processes within the heuristic-based scheduling task algorithm will lead to a different makespan on a heterogeneous computing system. Thus, a suitable algorithm for scheduling should set precedence efficiently for every subtask based on the resources required to reduce its makespan. This paper proposes a novel efficient scheduling task algorithm based on the coronavirus herd immunity optimizer algorithm to solve task scheduling problems in a cloud computing environment. The basic idea of this method is to use the advantages of meta-heuristic algorithms to get the optimal solution. We evaluate the performance of our algorithm by applying it to three cases. The collected findings suggest that the proposed strategy successfully achieved the best solution in terms of makespan, speedup, efficiency, and throughput compared to others. Furthermore, the results demonstrate that the suggested technique beats existing methods new genetic algorithm (NGA), proposed particle swarm optimization (PPSO), whale optimization algorithm (WOA), enhanced genetic algorithm for task scheduling (EGA-TS), gravitational search algorithm (GSA), genetic algorithm (GA), and hybrid heuristic and genetic (HHG) by 22.8%, 12.3%, 8.8%, 7.3%, 7.3%, 3.4%, and 3.4% respectively according to makespan.
CIDO: Chaotically Initialized Dandelion Optimization for Global Optimization
Authors: Akyol Sinem , Yildirim Muhammed , Alatas Bilal
Published: May 2023

Metaheuristic algorithms are widely used for problems in many fields such as security, health, engineering. No metaheuristic algorithm can achieve the optimum solution for all optimization problems. For this, new metaheuristic methods are constantly being proposed and existing ones are being developed. Dandelion Optimizer, one of the most recent metaheuristic algorithms, is biology-based. Inspired by the wind-dependent long-distance flight of the ripening seed of the dandelion plant. It consists of three phases: ascending phase, descending phase and landing phase. In this study, the chaos-based version of Chaotically Initialized Dandelion Optimizer is proposed for the first time in order to prevent Dandelion Optimizer from getting stuck in local solutions and to increase its success in global search. In this way, it is aimed to increase global convergence and to prevent sticking to a local solution. While creating the initial population of the algorithm, six different Chaotically Initialized Dandelion Optimizer algorithms were presented using the Circle, Singer, Chebyshev, Gauss/Mouse, Iterative and Logistic chaotic maps. Two unimodal (Sphere and Schwefel 2.22), two multimodal (Schwefel and Rastrigin) and two fixed-dimension multimodal (Foxholes and Kowalik) quality test functions were used to compare the performances of the algorithms. When the experimental results were analyzed, it was seen that the Chaotically Initialized Dandelion Optimizer algorithms gave successful results compared to the classical Dandelion Optimizer.
Nigeria Digital Terrestrial Television Broadcasting: An Evaluation of the Transmitted Signal received under different environmental features in North-Central Region
Authors: Jangfa Timothy Zhimwang , Ogherohwo Enoh Pius , O. Ezekiel Agbalagba , S. Onifade Yemi , O. Samuel Shaka , Aminu Ibrahim , Eshemokha Mamedu Christopher
Published: May 2023

The Government of Nigeria in the year 2016 switched from analog television broadcasting to digital terrestrial television broadcasting with the focus of providing reliable quality of television services to users. Regardless of the advantages of digital Terrestrial television system over analog television and efforts make by Nigeria Government to improve broadcasting, Signal reception is observed to be very poor. Therefore, this study aimed at monitoring, evaluating and mitigating environmental factors that cause signal degradation as well as attempting to provide solutions that will enhance the reception of signal even under severe environmental conditions. The transmitted signal of digital Terrestrial television was measured and received under different environmental features within the coverage area. The antenna radiation field was divided into four distinct regions (North-East, North-west, South-east and South-west of the transmitter) where the characteristics of the radiated wave are observed and measured starting from distance of 10km, 20km, 30km, 40km, 50km, up to 100km for each of the region. It was observed that the transmitted signal received at different distances varies depending on the physical features along the signal path. The result also shows that space loss increases with increase in distance. This study will guide DTT operators within the study area to precisely choose a site for installing the transmitting antenna for effective transmission.
A 1-Gram Sentiment Analysis Algorithm for Detecting Cyberbullying in Online Social Networks
Authors: Udanor C.N. , Eneh A.H. , D. Goji
Published: May 2023

Online social networking (OSN) sites in addition to providing business and recreational opportunities are fast becoming a breeding ground for cyberbullying activities. Cyberbullying is an act of harassing or insulting a person by sending messages that are hurting or threatening in nature using electronic communication. Such messages include threats, harassment, and humiliating messages to victims. Other forms are sexual harassments, sexual predating, etc. Cyberbullying poses threat to the physical and mental health of the victims. In this study, sentiments analysis was used to computationally recognize and categorize the opinions, views, and ideas expressed in a piece of text in social media to determine and establish whether the writer's attitude towards a particular topic, person, or a product is positive or negative. The study adopted both quantitative and qualitative approaches. Posts from Facebook were collected and analyzed. The software developed during the research was able detect the presence of cyberbullying in user contents. Results showed promising ability of the software to detect and suspend cyberbullying contents.
Enhancing the financial position of cities: Evidence from Mzuzu
Authors: Delbridge Victoria , Haas Astrid , Harman Oliver , Jangia Dyson , Venables Anthony
Published: May 2023

The case of Mzuzu illustrates how secondary cities, where revenues are often incredibly low and capacity is minimal, can innovate and lead the way on municipal finance reform. Mzuzu is Malawi’s third largest city. The focus of this case study is a simple and fit-for capacity property valuation system that increased realised revenues seven-fold between 2013 and 2018:1 The Revenue Mobilisation Programme (REMOP). Although the programme was initially seen to be a success, several serious misgivings continue to inhibit further progress. These centre on legal barriers in the current property valuation process in Malawi. More broadly, issues such as revenue pilferage, lack of capacity for financial anagement, land ownership disputes between spheres of government, and national rural bias continue to prevent Mzuzu from achieving a sustainable financial position. For development partners, the example of Mzuzu provides a stark reminder of the vital importance of widespread stakeholder engagement and caution for legal obstacles in order to achieve sustainable project success. It also illustrates the potential of using smaller cities, with more flexibility and somewhat strong incentives for reform, as a useful starting point to trial new revenue enhancement innovations. The Development Fund for Local Authorities (DFLA), a special entity set up for small and low-cost loans to local governments in Malawi, also presents an interesting model for further exploration. By helping local authorities through the process of lending, they are building local government creditworthiness and enabling them to develop systems for future debt finance. Malawi’s cities, being some of the poorest in the world and in a country with relatively low level of urbanisation, are still at the beginning of the development curve. This early stage brings numerous challenges that are yet to be faced as well as an enormous opportunity to learn from the mistakes and successes of other cities in similar contexts. The cities are still at the critical juncture where they can invest in the urban infrastructure essential for livability and productivity before mass settlement takes place.
Teoría del movimiento de un misil propulsado a reacción
Authors:   , Hunziker Raúl Ricardo
Published: May 2023

Contenido Prefacio, nomenclatura, introducción Parte I: Teoría general para los misiles de masa variable Ecuaciones generales de movimiento Expresiones para el vector, fuerza de Coriolis J y momento de Coriolis Parte II: Análisis crítico de las ecuaciones de movimiento generales y de los efectos especiales Introducción Movimiento del baricentro y del centro de reducción Ecuaciones del movimiento rotacional Otros efectos especiales. La reducción del sistema de fuerzas aerodinámicas Parte III: Efecto del viento Introducción Formulación aproximada de las ecuaciones de movimiento Cálculo del movimiento