bluuebunny/crossref_metadata_2025 huggingface dataset:
Michael Graves’s Portland Building
Authors: Clausen Meredith L.
Published: June 2014

Singled out as a landmark in architectural history even before it was built, Michael Graves’s Portland Building, known only through drawings, was considered an icon of postmodernism and immediately became a fixture in architectural history texts. Since it exploded onto the scene in the early 1980s, it has been heralded as one of the most controversial, published buildings in architectural history. But little has been written about the building itself, how it came to be, how well it functions, and how it has stood the test of time over the past thirty years. In Michael Graves’s Portland Building: Power, Politics, and Postmodernism, Meredith L. Clausen argues that despite the voluminous critical literature of theorists and critics focusing on its meaning, symbolism, associations, and reinterpretation of classicism, a decidedly different picture of the building emerges when viewed through the lens of historical documents. The focus here is on the dynamics of the competition, the conflicting civic priorities, the powerful role of the media, and politics both local and in architecture.
Endovascular Treatment of Carotid Artery Blowout Syndrome Caused by Oropharyngeal Carcinoma
Authors: Ergun Onur , Celtikci Pinar , Durmaz Hasan Ali , Birgi Erdem , Hekimoglu Baki
Published: June 2014

A 64-year-old man was admitted with massive hemoptysis caused by oropharyngeal carcinoma. Angiography revealed active extravasation from the left carotid bulb. Covered stent-graft placement resolved the bleeding, but the patient presented with recurrent hemorrhage two hours later and was treated with another stent-graft.
Creative Pedagogy - Supporting Children’s Creativity Through Drama
Authors: Toivanen Tapio , Halkilahti Laura , Ruismäki Heikki
Published: June 2014

Drama education is still a rather young field of science. Thus, there is an obvious need to conceptualize the elements and factors related to drama education fostering children’s creativity. What kind of learning environment supports children's creativity? Which aspects of drama education nurture children's creativity? Children’s creativity is often referred to as ‘little c creativity’, LCC. Subjectivity is an intrinsic character when defining children’s creativity since it is not determined by society. The article aims to perceive and build a theory of tuition supporting children’s creativity in the context of drama education. The objective of this theory-based article is to characterize the terminology of creativity in drama education. Based on prior research, the purpose of the article is to construct a model of tuition fostering children’s creativity. This theoretical model is contemplated through drama education. In a creative learning environment of drama the children are provided with rich experiences and their active role in learning is emphasized. Interaction is an essential part of learning process making learning itself a social activity. Creative environment supports children’s imagination and inner motivation. In addition, the atmosphere is permissive. These elements also create a potential for group creativity. According to research, the need to support children’s creativity is obvious. Furthermore, children’s creative development should be considered on two levels: the individual creativity of each pupil and the group creativity of the whole class. Drama education has the potential to nurture pupil’s creativity through its experiential, social and children-activating nature.
The Finnish Design of Folk High School Education
Authors: Ruokonen Pirkko Partanen , Ruokonen Inkeri , Ruismäki Heikki
Published: June 2014

In Finland, folk high school education began in 1889 and consisted of non-formal adult education in Finland. The aim of the study is to research the role of folk high school education into Finnish culture. The study introduces the history of Finnish folk high school education and discusses the role of folk high school education in the Finnish educational system, especially arts education. The purpose is to determine which developmental stages can be found in the history of Finnish folk high school education, and what role Finnish folk high school education played in the development of Finnish culture and arts education. The study approach is a historical-critical overview of the period from 1889 to 2012. Historical documents, archives and articles are content analysed to discover the trends influencing folk high school education, Finnish culture, and the arts in different time periods. The results show that Finnish folk high school education played a strong role in Finnish culture, especially in the education of people in rural areas. The influence on teachers’ education was found in both basic level and advanced education. The role of arts education, especially music education has been strong since 1970. The role and influence of Finnish folk high school education has been strong in Finnish society because it has been able to change and develop over time. Finnish folk high school education design has had a creative influence on the Finnish culture.
Визначення кількості пухлино-асоційованих макрофагів у хворих на рак шлунка
Authors: Bovkun L. V. , Sokolova I. E. , Gumenyuk L. D.
Published: June 2014

A direct correlation of tumour-associated macrophages (TAM) quantity and formation of metastasis in patients with gastric cancer was shown. Also the inverse relationship of life span and TAM quantity was determined. The studies were conducted on tumour tissue samples obtained from 37 operated patients. Quantity of TAM (%) in tumour tissues of patients with gastric cancer was determined by immunohistochemistry on paraffin sections. We used CD68 as the monoclonal antibodies. It was found that a high TAM level is a factor of unfavourable prognosis for a disease.
Можливі схильності до вживання психостимуляторів, токсичних, наркотичних речовин серед молоді та студентів
Authors: Ginzburg V. G. , Polichko T. N. , Polushkin P. M. , Galchenko D. V.
Published: June 2014

Taking into account modern achievements in medicine, psychology and sociology, the attempt at complex research of possible inclinations for psychostimulant, toxic agent and drug abuse among youths and students was made with the subsequent determination of the possible alternates of primary prevention. It is analysed the basic and additional risk factors promoting smoking, drinking, psychostimulant abuse, toxicomania and narcomania among young people. The dynamics of possible influences of medical, psychological and social factors is studied. The attempt of short-term prognostication and ranking was made.
Методичні підходи до оцінки впливу ксенобіотиків на білкові молекули
Authors: Gorelaya M. V.
Published: June 2014

It was tested and integrated the methodological approach to the research of xenobiotic compounds impact on protein molecules. For this purpose three groups of research methods were used: turbidimetry, immunochemistry and study of the impact on isoelectric point of proteins. The immunochemical methods are most specific. The turbidimetric methods are fastest and informative. Actually, the proposed methodological approach is integrated and versatile. These methods are effective for studying the xenobiotic influence on proteins in living organisms on the assumption of its complex applications. It was proved that this methodological approach is adequate, informative and easy to use.
Зв’язок концентрацій сперматозоїдів та іонів солей лужних металів у спермі
Authors: Maksymjuk H. V. , Vorobets Z. D. , Maksymjuk V. M.
Published: June 2014

It was found that destabilization of the low, medium and high concentrations of К+ in seminal fluid, spermatozoa and sperm is related to the hypo- and hyperfunctions of genitals’ generative tissues. The unmatched К+ concentrations and constant ratios of Са2+, К+ and Na+ under presence of normofunction and destabilization of their contents and ratios in seminal plasma and spermatozoa under hypo- and hyperfunction indicate that the features of ion homeostasis in sperm are programmed at the genetic level.
Зміни електрогіпокампограми та поведінкових реакцій щурів при посиленні протягом тривалого стресу ГАМК-ергічних механізмів мозку
Authors: Мelnikova O. Z. , Lyashenko V. P.
Published: June 2014

The changes of waves’ power and spectral composition of electrohippocampogram (EHpG) were analyzed in rats which brain GABA-ergic mechanisms increased by gidazepam and pyracetam during prolonged stress comparatively to the indices of EHpG under isolated affective influence. The nature of two-phase dynamics of the changes could indicate an adaptogenic action of drugs. It’s shown that modulation of central processes during prolonged stress and amplification of brain GABA-ergic mechanisms are accompanied by the changes of the animals’ behavioral reactions.
Сучасний стан і перспективи дослідження дерматогліфіки у практиці медико-психологічного обстеження студентів і молоді
Authors: Polushkin P. M. , Alsibay Е. V. , Nerovna E. V. , Shevchenko V. A.
Published: June 2014

The modern state and prospects of the medico-psychological examination of students and young people are analysed by a dermatoglyphics that allows drawing up the psychological portrait of a person. On the basis of typology of digital dermatoglyphics the development of the criteria system for prognostic estimation of physical capabilities of a human being is possible. According to the ratio of norm and pathology areas of the skin markings the hereditary diseases for future posterity, developmental abnormalities, different gene mutations, congenital development defects (limbs development defects as the special case), gender anomalies (sex determination), possible lethal cases, chromosome diseases and other cases can be forecasted with 99 % confidence.
Перспективи використання діагностичних та лікувальних препаратів бактеріофагів у медицині
Authors: Voronkova O. S. , Sirokvasha E. A. , Polishko T. N. , Vinnikov A. I.
Published: June 2014

The data on bacteriophage preparations, their features and benefits in comparison with other therapeutic agents are shown. The matters of phages production history to the present time are described. The data of phages application in clinical practice for the treatment, diagnostics, infections monitoring, sanitation of facilities and equipment, and conducting scientific research are shown. The benefits of phages drug are shown: affect only on specific sensitive bacteria, do not compromise the immunity, as opposed to antibiotics do not cause bacterial resistance, penetrate well into the humans and animals tissues, do not suppress the growth of normal flora and could be combined with any medication.
Зв’язок функціональної активності клітин-попередників кісткового мозку при хронічній мієлоїдній лейкемії з індивідуальною відповіддю на терапію
Authors: Diachenko M. V. , Borbulyak I. Z. , Bilko D. I. , Perekhrestenko T. P. , Tretyak N. M. , Dyagil I. S. , Bilko N. M.
Published: June 2014

The paper presents an effective method of the monitoring of individual response of the patients with chronic myeloid leukemia (CML) to the therapy with tyrosine kinase inhibitors (TKi). The growth patterns analysis of hematopoietic cells from CML patients showed that functional activity of bone marrow progenitor cells of the patients with complete response to TKi therapy was significantly lower (p < 0.05) in comparison with the colony-forming efficiency of bone marrow sampled from patients with a resistance to the therapy. The correlations were revealed between numbers of colony-forming units and the percentage of Ph+ cells in the bone marrow. This correlation was positive for the group of patients who were alternatively treated with the hydroxyurea and negative for the group of individuals with the resistance to TKi therapy.
Фізіологічна активність біопрепаратів стрептоміцету та комерційних препаратів відносно рослин квасолі (Phaseolus vulgaris)
Authors: Zhernosekova I. V.
Published: June 2014

Physiological activities of Streptomyces recifensis var. lyticus P3X, culture liquid biopreparations and commercial preparations of Heteroauxin and Emistim were studed in the haricot bean (Phaseolus vulgaris). Stimulation of plants’ morpho-biochemical indices by 20.2–176.3 % was shown after the application of streptomyces preparations. Commercial preparations had no stimulation effect of the plants, except the Emistim effect on germinating power. Heteroauxin and Emistim oppressed some biochemical indices of plants by 22.6–55.6 %.
Антиоксидантна система та азотистий обмін у крові кроликів за дії хлориду хрому
Authors: Iskra R. Y.
Published: June 2014

The effect of chromium chloride (Cr3+, 200 µg/kg of the combined feed) on the state of rabbits antioxidant system and amino transferases activity was studied. It was found that chromium entailed the increase of activity of catalase, glutathione peroxidase and the content of reduced glutathione in the animals’ blood. It was established that the activity of aspartate amino transferase in the exposured rabbits’ blood is greater than in the animals of control group.
Вплив локального рентгенівського опромінення на біоелектричну активність листя кукурудзи
Authors: Motsnyj M. P. , Botsva N. P. , Elina О. V. , Ulanova Y. A.
Published: June 2014

Dynamics of maize leaves biopotentials evoked by X-rays stimuli is analysed. Qualitative similarity in dynamics of plant’s bioelectrical response is determined. Hyperpolarization levels are quantitatively estimated for every series of the experiment. Dependence of the summarized hyperpolarization levels on photostimulus wave length is detected. The fact is ascertained that mean amplitude of hyperpolarization potentials reduces from 57.7 to 27.7 mV when the wave length decreases. Probable mechanisms of the initiation of photostimulated bioelectrical response are analysed.
Nanostructured, ITO-free electrodes for OLED emission control
Authors: Pradana Arfat , Kluge Christian , Gerken Martina
Published: June 2014

We demonstrated nanostructured, ITO-free anodes in flexible OLEDs using a combination of a composite organic-inorganic UV nanoimprint resist and a conductive, transparent polymer layer. Flexible OLEDs with grating anodes were fabricated on polycarbonate substrates. The nanoimprint resist was blended with 30% TiO2 nanoparticles in order to achieve a sufficient refractive index contrast to the polymer anode. It was periodically structured with a 370-nm period linear photonic crystal structure. PEDOT:PSS was spin-coated on as a polymer anode and structured in an oxygen plasma treatment. For OLED demonstration an organic emission layer (PPV-derivative “Super Yellow”) and a metal cathode (LiF/Al) were deposited. We observed successful waveguide mode extraction both in electroluminescence and photoluminescence for flat and bend substrates. The waveguide mode extraction angle varied slightly under bending. The combination of an inorganic-organic composite material with a conductive polymer transparent electrode is promising for improving the performance of ITO-free, flexible OLEDs.
The History, Physics, and Applications of the Smart-Cut® Process
Authors: Bruel Michel
Published: June 2014

In a silicon-on-insulator (SOI) structure, a thin layer of monocrystalline silicon rests on a dielectric layer—generally amorphous—itself on a silicon wafer. Because such a structure cannot be achieved by conventional methods, different ways had to be imagined to facilitate its construction.

The basic physics phenomenon that led the author to invent the process generally known under the name of Smart-Cut® is blistering. Blistering (Figure 1), in addition to flaking and exfoliation, is a visible macroscopic effect that has been known for a long time and is induced by high-dose implantations of inert gas or hydrogen ions in materials. These macroscopic effects result from the cooperative result of the microscopic effects induced in depth by penetration of particles. The microscopic effects of hydrogen or rare-gas implantation such as creation of microcavities, microblisters, or microbubbles (close to the penetration depth Rp corresponding to the maximum concentration) have been known for a long time. These microcavities enhance propagation of intercavity fractures where their density (depending on statistical fluctuations) reaches a percolation threshold. This leads to formation of a local cluster where all the microcavities are joined by a fractured zone, resulting in a blister at the surface. The driving force of this mechanism is the gas pressure in the microcavities and the stresses in the layer.
Beyond “Smart-Cut®” Recent Advances in Layer Transfer for Material Integration
Authors: Tong Q-Y. , Bower R.W.
Published: June 2014

Anintegratedsubstrate, consisting of more than one material or material structure, is highly desirable for optimizing performance of multiple-device types on a single chip or for growing high-quality heteroepitaxial films on compliant substrates. A typical integrated substrate contains a stack of thin layers of similar or dissimilar materials that are either amorphous, or poly- or single-crystalline with a variety of lattice constants or crystallographic orientations. Partially or fully processed device layers can also be transferred onto a desired substrate where the transferred device layer can be further processed on the opposite side of its original surface. In this article, we focus on issues related to layer transfer for material integration.

Layer transfer from a hydrogen (H)-implanted wafer onto a desired substrate by wafer bonding and layer splitting (the so-called “Smart-Cut®” method) is an attractive approach to prepare integrated materials, such as-silicon-on-insulator (SOI), SiC or GaAs on oxidized silicon, and Ge on glass.
Polymer Electroluminescent Devices
Authors: Yang Yang
Published: June 2014

Electroluminescence (EL) is the emission of light generated from the radiative recombination of electrons and holes electrically injected into a luminescent semiconductor. Conventional EL devices are made of inorganic direct-bandgap semiconductors, such as GaAs and InGaAs. Recently EL devices based on conjugated organic small molecules and polymers have attracted increasing attention due to easy fabrication of large areas, unlimited choice of colors, and mechanical flexibility. Potential applications of these organic/polymeric EL devices include backlights for displays, alphanumeric displays, and high-density information displays.

Electroluminescence from an organic material was first demonstrated in the 1960s on anthracene crystals by Pope et al. at New York University. Subsequently several other groups also observed this phenomenon in organic crystals and thin films. These organic EL devices had high operating voltages and low quantum efficiency. Consequently they did not attract much attention. In 1987 a breakthrough was made by Tang and VanSlyke at Eastman Kodak who found that by using multilayers of sublimated organic molecules, the operating voltage of the organic EL devices was dramatically reduced and the quantum efficiency was significantly enhanced. This discovery touched off a flurry of research activity, especially in Japan. The Japanese researchers, as welt as the group at Kodak, have since improved the device efficiency and lifetime to meet commercial requirements. This progress is reviewed by Tsutsui in this issue.
Deposition and Applications of Quasicrystalline Coatings
Authors: Besser M.F. , Eisenhammer T.
Published: June 2014

The key to engineering a material lies in exploiting its beneficial characteristics while minimizing its inherent weaknesses. Whether the weakness is, for example, poor corrosion resistance or low hardness, applying a relatively thin coating of another material that mitigates the shortcoming of the underlying material is a practical solution allowing the composite pieces to be used in demanding environments. This method has been utilized in a wide variety of cases ranging from paint on wooden fences and ceramic thermal barriers on single-crystal superalloy turbine blades to tungsten carbide hard-facing layers on drilling equipment. Some materials may suffer from high cost and therefore are used as a thin layer to impart their desired properties. For instance, gold leaf is applied to buildings for appearance while diamond films are deposited onto normal cutting tools to improve their performance. The specific application typically dictates both the material and the deposition method for the coating. The gold leaf does not need to offer much resistance to abrasion or mechanical stress in order to maintain its beautiful shine far into the future. In contrast the diamond film must be strongly adhered to the underlying cutting tool surface if it is to survive the punishing wear and thermal stresses of machining operations.
Hydrogen Storage in Quasicrystals
Authors: Kelton K.F. , Gibbons P.C.
Published: June 2014

Quasicrystals may have important applications as new technological materials. In particular, work in our laboratory has shown that some quasicrystals may be useful as hydrogen-storage materials.

Some transition metals have a capacity to store hydrogen to a density exceeding that of liquid hydrogen. Such systems allow for basic investigations of solid-state phenomena such as phase transitions, atomic diffusion, and electronic structure. They may also be critical materials for the future energy economy. The depletion of the world's petroleum reserves and the increased environmental impact of conventional combustion-engine powered automobiles are leading to renewed interest in hydrogen. TiFe hydrides have already been used as storage tanks for stationary nonpolluting hydrogen internal-combustion engines. Nickel metal-hydride batteries are commonly used in a wide range of applications, most notably as power sources for portable electronic devices—particularly computers. The light weight and low cost of titanium-transition-metal alloys offer significant advantages for such applications. Unfortunately they tend to form stable hydrides, which prevents the ready desorption of the stored hydrogen for the intended use.

Some titanium/zirconium quasicrystals have a larger capacity for reversible hydrogen storage than do competing crystalline materials. Hydrogen can be loaded from the gas phase at temperatures as low as room temperature and from an electrolytic solution. The hydrogen goes into solution in the quasicrystal structure, often avoiding completely the formation of undesirable crystalline hydride phases. The proven ability to reversibly store variable quantities of hydrogen in a quasicrystal not only points to important areas of application but also opens the door to previously inaccessible information about the structure and dynamics of this novel phase. Selected results illustrating these points appear briefly here.
Particle-Packing Phenomena and Their Application in Materials Processing
Authors: Dinger Dennis R. , Funk James E.
Published: June 2014

Particle packing is directly controlled by the particle-size distribution of a material being processed. For this reason, particle packing is important to all particulate/fluid systems. After the solids fraction of a body is defined, interparticle chemistry controls how the body will pack and flow. A system of powders can never pack better than the maximum possible level defined by the particle-size distribution alone. Proper control of interparticle chemistry however can help achieve maximum packing, can be used to open the structure, and/or can be used to modify rheological or other process properties.

The main goals of particle-packing research have been to determine how systems of particles pack, to develop algorithms for calculating packing densities and porosities for any distribution of particles (spherical or nonspherical, rough or smooth, wet or dry), and to determine how packing and its properties affect the variety of industrial operations that utilize particulate/fluid systems.
Characterization and Control of Compact Microstructure
Authors: Lannutti J.J.
Published: June 2014

The microstructure and properties of a ceramic component are largely predetermined by the processes and process controls used to manufacture them. The metric for success in manufacturing is often based on gross density. For example, optimizing pressure-density response, maximizing overall density, and minimizing springback and delaminations in powder pressing all focus on characterization and control of the overall (macroscopic) state of a powder compact. Unfortunately this focus on macroscopic effects has contributed to a general neglect of the compact at the microstructural level. Process-control variables in powder compaction have been defined and discussed by many workers, but their quantitative application to predict and control compaction behavior is limited. Advances in characterization technology and computer modeling now allow us to quantitatively characterize and simulate microstructures more easily. These and other tools can help provide the scientific and technological foundation necessary to predict and control microstructure and microstructural evolution during processing.
High Temperature Superconductors, Physics Funding, Materials Physics Highlighted at American Physical Society Meeting
Authors: Kaufmann E.N.
Published: June 2014

The March meeting of the American Physical Society was held in New Orleans, March 21-25, 1988. The primary forum for APS's Division of Condensed Matter Physics, the meeting occupied the entire five days with sessions begining at 8:00 a.m., 11:00 a.m., and 2:30 p.m. Special sessions ran during dinner hours and some technical topics required evening sessions as well. According to the meeting program (an 8.5 × 11 inch book not quite 1.5 inches thick), 340 invited and 3,420 contributed abstracts were scheduled into 392 sessions. A gargantuan event to say the least. Meeting rooms were full to over-flowing for many sessions with the hottest, most pervasive topic of the week being high temperature superconductors.

Formed just three years ago, the Materials Physics Topical Group (MPTG) of the American Physical Society is thriving. At the meeting, the MPTG fielded 15 topically focused symposia comprising about 50 sessions ranging from quasicrystals to high temperature superconductors. Both invited and contributed sessions were included (the latter often featuring an invited lead-off talk). The sessions were developed through the efforts of symposium organizers in a manner not dissimilar to the way MRS symposia are run. Although there is overlap between MPTG programs and some areas treated by the APS's Condensed Matter Physics Division (CMP), this style of symposium organization is unique to MPTG.
Occurrence of Eretmocerus mundus Mercet (Hymenoptera: Aphelinidae) parasitizing Bemisia tabaci (Genn.) biotype B (Hemiptera: Aleyrodidae) in Brazil
Authors: Lourenção André Luiz , Costa Valmir Antonio , Pereira Lillian Silveira , Prado Juliana Cardoso
Published: June 2014

The parasitism of Bemisia tabaci (Genn.) biotype B nymphs on cotton plants was observed during a research on resistance of cotton genotypes to this whitefly. The experiment was set in a greenhouse at the Experimental Station of the Instituto Agronômico (IAC), in Campinas, São Paulo State, Brazil. Samples of the parasitized nymphs were collected and maintained in laboratory to monitor the parasitism and obtain the adult parasitoids. A total of 129 adult parasitoids were obtained, including one Encarsia inaron (Walker), 13 En. lutea (Masi), and 115 Eretmocerus mundus Mercet (Hymenoptera: Aphelinidae). This is the first report of Er. mundus in Brazil.
PROBABILISTIC TIME VARIANT ASSESSMENT OF THIN-WALLED STEEL MEMBERS UNDER ATMOSPHERIC CORROSION ATTACK
Authors: Cascini Lucrezia , Portioli Francesco , Landolfo Raffaele
Published: June 2014

Atmospheric corrosion is a relevant problem for steel structures and components exposed in aggressive environment in case of poor and/or unfeasible maintenance and inspection during service life. As for thin-walled members, the corrosion hazard can be exacerbated due to the thin thickness of components and the coupled effect between corrosion and buckling can significantly reduce the structural capacity of such structures. Following these considerations, this paper presents a study on the reliability of a thin-walled steel section subjected to the damage induced by atmospheric corrosion in outdoor environments, combining predictive corrosion models for metals with structural reliability applications. A general procedure for the evaluation of the time variant capacity is proposed and discussed in detail. Finally, an application to a C-lipped cold formed section is presented and a reliability analysis of the deteriorating section is carried out to evaluate the coupled effect of corrosion and buckling, according to the proposed procedure.
ANALYSIS OF LOADS AND STRUCTURAL CAPACITY OF STEEL SILO WITH CORRUGATED WALL FOR PELLETED MATERIAL
Authors: Antonowicz Ryszard , Bywalski Czesław , Kaminski Mieczysław
Published: June 2014

This paper deals with problems connected with the design and operation of thin-walled steel silos for storing pelleted materials. A failure of a faultily designed silo is described and its causes are examined. The parameters of the stored material were determined. The exceptional (unforeseen) loads produced by arching and their consequences were analysed. In order to compare the effect of calculation assumptions on the degree of use of the load-bearing capacity of the stringer its buckling capacity under the stored material load alone was checked. On the basis of the analyses the probable course of the events leading to the failure was determined. It is pointed out that the exceptional loads and the disturbance of the bulk material flow by silo structural and technological fittings need to be taken into account in the design of silos.
A LIFE DEDICATED TO SCIENCE: ON THE OCCASION OF THE 70TH BIRTHDAY OF EDITOR-IN-CHIEF EDMUNDAS KAZIMIERAS ZAVADSKAS
Authors: Kačianauskas Rimantas , Kaklauskas Arturas , Skibniewski Mirosław J. , Kaklauskas Gintaris , Antuchevičienė Jurgita , Tūpėnaitė Laura
Published: June 2014

„A life dedicated to science: on the occasion of the 70thbirthday of Editor-in-Chief Edmundas Kazimieras Zavadskas" Journal of Civil Engineering and Management, 20(3), p. 311-314
UNIFORM PRICE AUCTION OF DIVISIBLE GOODS BASED ON MULTIPLE ROUNDS LINEAR BIDDING AND ITS EQUILIBRIUM ANALYSIS
Authors: RAO Congjun , ZHAO Yong , CHEN Yang
Published: June 2014

In this paper, the auction problem of a kind of continuous homogeneous divisible goods is studied and a uniform price auction mechanism is presented based on three conditions, i.e. the auctioneer’s supply is variable, every bidder submits multiple rounds continuous linear bidding, and every bidder’s valuation to per unit of the goods is independent private information. Concretely, two key problems, i.e. the bidders’ asymptotic strategic behaviours and forming process and composition of equilibrium points are explored. The conclusion is drawn that different bidders’ bidding order and different starting points of initial bidding would not cause different local equilibrium points, and if the equilibrium points exist, then the equilibrium point is unique.
Chronic pelvic pain: comorbidity between chronic musculoskeletal pain and vulvodynia
Authors: Biasi G. , Di Sabatino V. , Ghizzani A. , Galeazzi M.
Published: June 2014

Chronic pelvic pain (CPP) is a common condition that has a major impact on the quality of life of both men and women. Male CPP is usually attributable to well-defined urogenital conditions (most frequently infectious/non infectious prostatic diseases) or musculoskeletal or bowel diseases, whereas the features of female CPP are much more complex and are of particular clinical and epidemiological importance. It is a multifactorial syndrome that can be due to diseases of the urogenital, gastrointestinal, or musculoskeletal systems, or to neurological or neuropsychiatric disorders. It is not always easy to identify its predominant pathogenesis, although it often occurs as a central sensitization syndrome triggered by an initial stimulus which is no longer detectable and only manifests itself clinically through pain. In this respect, there are some very interesting relationships between vulvodynia and fibromyalgic syndrome, as identified in a preliminary study of women with chronic musculoskeletal pain in which it was demonstrated that vulvar pain plays an important role, although it is often overlooked and undiagnosed.
Anxiety and depression in rheumatologic diseases: the relevance of diagnosis and management
Authors: Torta R. , Pennazio F. , Ieraci V.
Published: June 2014

The high prevalence of emotional disorders (anxiety, chronic stress, mood depression) in patients with pain during rheumatologic diseases (particularly fibromyalgia) is closely related to the common pathogenic mechanisms concerning emotions and pain. Therefore a prompt identification of any psychic component of pain, also by means of specific tools, is a must, because it can require an adjustment of the therapeutic approach by combining both an analgesic treatment and antidepressants and/or psychotherapeutic strategies.
IRON CHELATION THERAPY WITH DEFERASIROX IN THE MANAGEMENT OF IRON OVERLOAD IN PRIMARY MYELOFIBROSIS
Authors: Elli Elena Maria , Belotti Angelo , Aroldi Andrea , Parma Matteo , Pioltelli Pietro , Pogliani Enrico Maria
Published: June 2014

Deferasirox (DSX) is the principal option currently available for iron-chelation-therapy (ICT), principally in the management of myelodysplastic syndromes (MDS), while in primary myelofibrosis (PMF) the expertise is limited. We analyzed our experience in 10 PMF with transfusion-dependent anemia, treated with DSX from September 2010 to December 2013. The median dose tolerated of DSX was 750 mg/day (10 mg/kg/day), with 3 transient interruption of treatment for drug-related adverse events (AEs) and 3 definitive discontinuation for grade 3/4 AEs. According to IWG 2006 criteria, erythroid responses with DSX were observed in 4/10 patients (40%), 2 of them (20%) obtaining transfusion independence. Absolute changes in median serum ferritin levels (Delta ferritin) were greater in hematologic responder (HR) compared with non-responder (NR)  patients, already at 6 months of ICT respect to baseline. Our preliminary data open new insights regarding the benefit of ICT not only in MDS, but also in PMF with the possibility to obtain an erythroid response, overall in 40 % of patients. HR patients receiving DSX seem to have a better survival and a lower incidence of leukemic transformation (PMF-BP). Delta ferritin evaluation at 6 months could represent a significant predictor for a different survival and PMF-BP.  However, the tolerability of the drug seems to be lower compared to MDS, both in terms of lower median tolerated dose and for higher frequency of discontinuation for AEs. The biological mechanism of action of DSX in chronic myeloproliferative setting through an independent NF-κB inhibition could be involved, but further investigations are required.
Ketoconazole Inhibits Ovulation as a Result of Arrest of Follicular Steroidogenesis in the Rat Ovary
Authors: Gal Michael , Orly Joseph
Published: June 2014

Objective

Ketoconazole (KCZ) is a known inhibitor of steroidogenic P450 enzymes in the adrenal cortex and the gonads. Previous studies examined the potential clinical use of KCZ for attenuation of ovarian response to gonadotropin treatments. This study aimed to use the superovuating rat model to explore the effect of KCZ on ovarian steroidogenesis, follicular function, and development toward ovulation.

Methods

Prepubertal rats were treated with equine chorionic gonadotropin (eCG)/human CG (hCG) resulting in multiple follicular development and ovulation. The effect of KCZ on this model was examined by administration of KCZ-gel formula and subsequent analyses of ovarian steroidogenesis, rate of ovulation, morphometric assessments of follicular parameters, and cell-specific steroidogenic maturation of the treated ovaries.

Results

When applied shortly before gonadotropin stimulation, KCZ markedly reduced ovarian progesterone, androstenedione, and estradiol levels down to 18.7, 36.5, and 19.0%, respectively ( P < 0.001). A single KCZ-gel administration of 6, 12, and 24 mg/rat resulted in reduction of ovulated ova/ovary down to 8.6 ± 4.9, 5.1 ± 4.3, and 2.4 ± 3.2, respectively, as compared to 13.6 ± 4.4 ova found in the oviduct of control-gel-injected animals ( P < 0.001). An alternative protocol made use of small KCZ doses injected in non-gel formula (5 mg/dose/8 hours), commenced with the eCG administration and terminated 24 hours later; this treatment readily inhibited the ovulation rates to 6.6 ± 6.6 as compared to 16.5 ± 4.1 ova/ovary in the control group ( P < 0.01). By contrast, KCZ failed to inhibit ovulation if administered 24 hours after eCG injection. Anovulation by KCZ resulted from arrest of follicular development at the stage of 800-840 μm Graafian follicles as compared to 920 μm of peri-ovulatory follicles (OFs) observed in the control group, P = 0.029. In addition, absence of CYP11A1 expression was evident in the granulosa cell layers of the growth-arrested follicles, which also lacked mucified mature cumulus cell complexes.

Conclusion

These results suggest that KCZ-mediated inhibition of follicular maturation probably results from impaired steroidogenesis at early phase of follicular development toward ovulation. Hence, attenuation of folliculogenesis by KCZ may be harnessed to modulate gonadotropin-ovarian stimulation in fertility treatments.
Mobile Libraries: Librarians’ and Students’ Perspectives
Authors: Aharony Noa
Published: June 2014

This study which is based on the Technological Acceptance Model (TAM), seeks to explore whether librarians and LIS students are familiar with the newest technological innovations and whether they are ready to accept them. The research was conducted in Israel during the first and second semesters of the 2012 academic year and considered two populations: librarians and LIS students. Researchers used two questionnaires to gather data: a personal details questionnaire, and a mobile technology questionnaire. On the whole, the current study supported the two core variables of the TAM (perceived ease of use and usefulness), as well as personal innovativeness that may predict librarians’ and students’ behavioral intention to use mobile services in the library.
A Comparison of Evidence-Based Practice and the ACRL Information Literacy Standards: Implications for Information Literacy Practice
Authors: Adams Nancy E.
Published: June 2014

Evidence-based practice (EBP), like information literacy, is concerned with an individual’s knowledge, skills, and attitudes relating to using information. EBP is now a professional competency in fields as diverse as social work, nursing and allied health fields, and public policy. A comparison of the Association of College and Research Libraries’ Information Literacy Competency Standards for Higher Education with the commonly accepted EBP model shows congruence, but the two models diverge in their use of authority of the producer as a marker of information quality and in their relative emphasis on formulation of the research question and application of information.
Commercial Database Design vs. Library Terminology Comprehension: Why Do Students Print Abstracts Instead of Full-Text Articles?
Authors: Imler Bonnie , Eichelberger Michelle
Published: June 2014

When asked to print the full text of an article, many undergraduate college students print the abstract instead of the full text. This study seeks to determine the underlying cause(s) of this confusion. In this quantitative study, participants (n=40) performed five usability tasks to assess ease of use and usefulness of five commercial library databases and were surveyed on their understanding of library terminology. The study revealed that more than half of the students correctly defined the term “Abstract” and over 75 percent understood “full text.” However, only 25 percent of the students were able to successfully complete all five database tasks.
Teaching Outside the Box: ARL Librarians’ Integration of the “One-Box” into Student Instruction
Authors: Kulp Christina , McCain Cheryl , Scrivener Laurie
Published: June 2014

This article reports the results of a survey that targeted reference and instruction librarians who work at libraries that are members of the Association of Research Libraries (ARL). Respondents were asked to indicate whether or not they teach students to use the one-box tool, and why or why not. Based on the responses of the 352 librarians who participated in the study, the researchers found that most reference and instruction librarians at ARL libraries are “teaching outside the box.”
Framing Librarianship in the Academy: An Analysis Using Bolman and Deal’s Model of Organizations
Authors: Fleming-May Rachel A. , Douglass Kimberly
Published: June 2014

Since the earliest days of the profession, academic librarians have attempted to reconcile their status within the academy. This project takes a new approach to this effort by using Lee Bolman and Terrence Deal’s “Four Frames” model to analyze the issues. To more closely examine the dynamics, tensions, and implications associated with librarians’ professional status within the academy, we discuss the role of the academic librarian in the context of each of Bolman and Deal’s frames: Structural, Human Resource, Political, and Symbolic. In this discussion, we demonstrate that librarians are positioned to address human resource (as defined by Bolman and Deal), political, and symbolic factors contributing to their status within the academy. Also, while we establish that the relationship between library faculty and disciplinary faculty plays a role in library faculty status, we conclude that library faculty status is constructed by a number of forces. We further conclude that many of the political and symbolic conditions experienced by librarians are rooted in structural and human resource factors controlled by upper-level administration in both libraries and the universities.
Surface nitrification: A major uncertainty in marine N2O emissions
Authors: Zamora Lauren M. , Oschlies Andreas
Published: June 2014

The ocean is responsible for up to a third of total global nitrous oxide (N2O) emissions, but uncertainties in emission rates of this potent greenhouse gas are high (>100%). Here we use a marine biogeochemical model to assess six major uncertainties in estimates of N2O production, thereby providing guidance in how future studies may most effectively reduce uncertainties in current and future marine N2O emissions. Potential surface N2O production from nitrification causes the largest uncertainty in N2O emissions (estimated up to ~1.6 Tg N yr−1 or 48% of modeled values), followed by the unknown oxygen concentration at which N2O production switches to N2O consumption (0.8 Tg N yr−1 or 24% of modeled values). Other uncertainties are minor, cumulatively changing regional emissions by <15%. If production of N2O by surface nitrification could be ruled out in future studies, uncertainties in marine N2O emissions would be halved.
Evidence that Agulhas Current transport is maintained during a meander
Authors: Leber Greta M. , Beal Lisa M.
Published: June 2014

In April 2010, full‐depth hydrographic and direct velocity measurements across a solitary meander in the Agulhas Current were collected at nominally 34∘S. During a second cruise in November 2011, a transect across the nonmeandering Agulhas Current was captured. These data provide the first full‐depth, in situ picture of the meandering Agulhas Current and allow us to investigate how the velocity structure and transport of the meandering current differs from its nonmeandering state. An analysis of the horizontal momentum equations show that the meander is in geostrophic balance. However, sampling bias causes large differences between geostrophic and direct velocity measurements during meandering, especially near the surface. As the current meanders offshore, its core speed weakens by more than 70 cm s−1 and its width broadens by almost 40 km. These two effects compensate so that the southwestward transport of the Agulhas current is largely unchanged during meandering. At the same time, the meander generates a strong inshore counterflow, which weakens the net Eulerian transport across the 300‐km line by almost 20 Sv.
Cobalt complex bearing β‐ketoamine ligand: syntheses, structure, catalytic behavior for styrene and methyl methacrylate polymerization
Authors: Jie Gao , Feng Bao , Ying Chen , Tao Chen , Rui Ma , Pan Liu , Xiaobing Han , Zhenzhen Lan , Jianlan Ma , Chunjie Yan
Published: June 2014

Cobalt complex based on β‐ketoamine ligand [(Z)‐4‐((2,5‐dimethylphenylamino) (phenyl)methylene)‐3‐methyl‐1‐phenyl‐1H‐pyrazol‐5(4H)‐one] was successfully synthesized. The produced catalyst showed satisfactory activities in the cobalt‐mediated radical polymerization of styrene and methyl methacrylate with the common initiator of AIBN. The resulting polymerizations have the characteristics of living radical polymerization and displayed a nearly linear correlation between the number‐average molecular weight and monomer conversion. Low polydispersity was obtained for all polymerizations, and the polydispersity index decreased with the increase of conversion. These improvements facilitate the implementation of styrene and methacrylate cobalt‐mediated radical polymerization, and open the door to the scale‐up of the process. Copyright © 2014 John Wiley & Sons, Ltd.
Comparison of the antibacterial activity of modified‐cotton with magainin I and LL‐37 with potential as wound‐dressings
Authors: Pedrosa Marta , Mouro Cláudia , Nogueira Frederico , Vaz Joana , Gouveia Isabel
Published: June 2014

Wounds are the ideal setting for the development of micro‐organisms, so it is often necessary to apply a dressing to control bacterial colonization. Cotton is commonly used in dressings, as it exhibits important hydrophilic characteristics such as high moisture and fluid retention properties, but it may provide a sustainable media for the development of micro‐organisms. In this way, the development of new strategies to provide cotton materials with lasting and effective antimicrobial properties is of the utmost importance. Consequently, here we described two processes to develop cotton‐dressings functionalized with antimicrobial peptides (AMPs) magainin I (MagI) and LL‐37, in order to give cotton‐dressings an antibacterial effect. The AMPs showed no cytotoxic effect against human fibroblasts so they are safe to contact with skin. In addition, the functionalized materials with either LL‐37 or MagI present an antimicrobial effect exhibiting inhibition ratios of 89% against Klebsiella pneumoniae and 58% against Staphylococcus aureus, respectively. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40997.
Thermoresponsive poly(γ‐propyl‐l‐glutamate)‐graft‐(oligo ethylene glycol)s: Synthesis, characterization, and properties
Authors: Wu Yan , Deng Yong , Yuan Qiulin , Ling Ying , Tang Haoyu
Published: June 2014

A series of thermoresponsive poly(γ‐propyl‐L‐glutamate)‐graft‐(oligo ethylene glycol)s (PPLG‐g‐OEGs) with different main‐chain and side‐chain lengths have been synthesized via copper‐mediated alkyne‐azide 1,3‐dipolar cycloaddition between poly(γ‐azidopropyl‐L‐glutamate)s (PAPLG) and propargyl terminated oligo ethylene glycols (Pr‐OEGs). Fourier transform infrared spectrometer analysis revealed that PAPLG10 adopted 39.4% β‐sheet, 47.4% α‐helix, and 13.2% random coil while PAPLG with longer main‐chain length (DP = 37 and 88) and PPLG‐g‐OEGs adopted exclusive α‐helix in the solid state. Circular dichroism analysis revealed that PPLG‐g‐OEGs adopted α‐helical conformations with helicities in the range of 50∼100%. The thermoresponsive behaviors of PPLG‐g‐OEGs in water have been studied by dynamic light scattering. The polymer concentration, main‐/side‐chain length, and helicity collectively affected their cloud point temperatures. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 41022.