bluuebunny/crossref_metadata_2025 huggingface dataset:
Human leukocyte antigen class II (DRB1 and DQB1) alleles frequencies in patients with various forms of pemphigus among the Russian population
Authors: Olisova Olga Yu. , Lepekhova Anfisa A. , Dukhanin Alexander S. , Teplyuk Natalia P. , Shimanovsky Nikolay L.
Published: May 2024

BACKGROUND: Autoimmune bullous dermatoses are known to be the most severe blistering conditions of skin. HLA-DRB1 and DQB1 alleles might play a crucial role in their onset. In pemphigus HLA class II molecules stimulate the division of T helper cells, which in turn stimulate B cells to produce antibodies to epidermal keratinocytes causing acantholysis. The HLA-DRB1 and DQB1 alleles’ frequencies studied in pemphigus in a vast variety of populations worldwide. However, as of yet, this mechanism was not investigated in Russian population.
AIM: To estimate the prevalence of the HLA-DRB1 and DQB1 alleles at a low- and high-resolution levels in patients with various forms of pemphigus. We observed 86 patients with pemphigus vulgaris, 13 ― with pemphigus foliaceus, 6 patients with paraneoplastic pemphigus and 92 healthy volunteers.
MATERIALS AND METHODS: HLA typing for DRB1 and DQB1 was performed with 50 nanogram DNA extraction and polymerase chain reaction.
RESULTS: At a low-resolution level HLA-DRB1*4 and DRB1*14 alleles were statistically significant more frequent in pemphigus vulgaris and pemphigus foliaceus patients compared to those in control subjects, whereas HLA-DRB1*11, DRB*16, and DRB1*3 alleles were more frequent in healthy volunteers. At a high-resolution level, DRB1*04:02 allele was observed to show its statistically significant higher frequency in all variants of pemphigus, including paraneoplastic pemphigus. However, DRB1*14:05 HLA allele was more frequent in pemphigus vulgaris and pemphigus foliaceus patients, whereas DRB1*11:04 one was found to be 3.7 times more frequent in healthy controls. Additionally, at a low-resolution level for HLA-DQB1 alleles no statistically significant results were observed. However, at a high-resolution level the chances for more frequent indication of DQB1*03:02 allele were 7.09 times higher in pemphigus foliaceus group and 2.49 higher in pemphigus vulgaris patients compared to healthy volunteers. Moreover, DQB1*05:03 was identified more frequently in pemphigus vulgaris and paraneoplastic pemphigus groups of patients, whereas DQB1*03:01 allele was shown to be increased in the group of healthy donors.
CONCLUSION: HLA-DRB1*4, DRB1*14, DRB1*04:02, DRB1*14:05, DQB1*03:02 and DQB1*05:03 alleles might be considered as the genetic markers for pemphigus vulgaris susceptibility, while HLA-DRB1*11, DRB*16, DRB1*3, DRB1*11:04 and DQB1*03:01 allelic groups appear to be protective for Russian population.
On the issue of the effectiveness and bioequivalence of isotretinoin Lidose
Authors: Olisova Olga Yu. , Kukes Ilya V.
Published: May 2024

BACKGROUND: Acne is one of the most common types of dermatoses. Systemic isotretinoin treatment, which affects all mechanisms of acne pathogenesis, is the most effective drug for severe acne treatment. This study presents scientific data on the innovative formulation of isotretinoin for acne treatment using the patented Lidose technology. The use of lidose isotretinoin allows for the reduction of the amount of isotretinoin used by the patient by 20% without losing its therapeutic effectiveness.
AIM: This study aimed to analyze comparative studies of bioavailability and relevant pharmacokinetic parameters, which made it possible to prove that initial dosages of 8 and 16 mg of lidose isotretinoin (Aknecutan) are bioequivalent to 10 and 20 mg of the usual isotretinoin preparations. The study also aimed to evaluate the efficacy and safety of the drug.
MATERIALS AND METHODS: Over the past 7 years, 1044 patients (women, n = 651, 62.4%; men, n = 393, 37.6%) have received acne treatment using new formulations of isotretinoin (lidose isotretinoin, Aknecutan) for moderate to severe acne at a daily dose of 0.4–0.8 per 1 kg of body weight with a total drug dose of 100–120 mg/kg per course of therapy.
RESULTS: The study demonstrated the bioequivalence of 8 and 10 mg lidose isotretinoin (Aknecutan) to the usual preparations of 10 and 20 mg isotretinoin, respectively. After therapy, clinical remission was achieved in all patients, which required 7–12 months of treatment, depending on the daily drug dose. Among the side effects, cheilitis and retinoic dermatitis of the face was observed, which were completely resolved by use of moisturizing creams and moisturizing sticks. An increase in the levels of liver enzymes, triglycerides, and lipoproteins was observed in 5–10% of patients, which did not exceed 20–30% of the norm and did not require discontinuation of therapy. After the treatment, these indicators returned to normal levels. Other side effects were extremely rare. Notably, disease relapses are most often caused by a low total dose of the drug or the presence of endocrinological and gynecological diseases.
CONCLUSION: The innovative lidose isotretinoin is one of the most highly effective and safe systemic retinoids for the treatment of moderate to severe acne. Comparative studies of bioavailability and corresponding pharmacokinetic parameters have demonstrated the bioequivalence of the new formulation of isotretinoin (Aknecutan) for acne treatment, which fully corresponds to that of the original preparation.
Intra-UE Movement of Dogs and Cats by Animal Shelters in the Light of Veterinary Law
Authors: Kudasik-Gil Emilia , Gruszczyńska Agnieszka
Published: May 2024

The aim of the article is to analyze the not previously discussed problem of the application of legal provisions regarding the movement of dogs and cats by Polish animal shelters to other EU Member States. This matter is regulated in EU law, as well as in Polish law, and its complexity, overlapping standards and emerging uncertainty regarding their application by state administration justifies taking up this topic. The analysis covers veterinary requirements for shelters from which dogs or cats are moved to other EU Member States, as well as requirements relating to the identification and health of the animals themselves. An important problem that has been revealed is the application of regulations regarding the approval of this type of establishments by official veterinarians without giving priority to EU law. Polish authorities that approve animal shelters require operators running these establishments to meet the Polish law requirements, which, however, do not result from EU regulations. These may lead to discrimination against Polish establishments running animal shelters.
Rubrica: Recurso na avaliação do aprendizado da anamnese no curso de Medicina
Authors: Oliveira Juliana Lara de , Rocha Gladys , Alavarse Ocimar Munhoz
Published: May 2024

Neste artigo apresentamos e discutimos um instrumento para subsidiar a avaliação do aprendizado de estudantes do curso de Medicina na competência de realização da anamnese. Trata-se de uma rubrica para padronizar o levantamento de informações por parte dos preceptores desse curso, que visa a ampliar as possibilidades de tal avaliação, minimizando situações de acentuada subjetividade, contribuindo, assim, para o desenvolvimento dessa competência, extremamente importante na formação médica. A avaliação, como uma forma de qualificar um objeto educacional e emitir um juízo de valor sobre ele, é parte essencial do processo pedagógico, no entanto muitos professores não recebem preparação para realizá-la, o que acaba por comprometer a validade e a fidedignidade e por limitar o potencial da avaliação no ensino.
MULTIMODALIDADE E O USO DE ESTACIONAMENTOS A FAVOR DAS CONEXÕES COM TRANSPORTE PÚBLICO
Authors: Pavelski Luziane Machado , Bernardinis Marcia Pereira de Andrade
Published: May 2024

Poluição, exclusão social e prejuízos econômicos oriundos da falta de mobilidade, somados a perspectiva de um agravamento futuro devido ao aumento populacional impulsionam a procura de soluções. Nesse sentido, as diretrizes da mobilidade sustentável têm apresentado alternativas promissoras, dentre as quais a multimodalidade é uma delas. Dividido em duas partes principais, o presente artigo através de um enfoque pouco explorado, o uso dos estacionamentos no favorecimento do transporte multimodal, apresenta o caso de Curitiba. Em um primeiro momento, através de uma revisão teórica, destaca o que está previsto no Plano Diretor da cidade a respeito da inclusão dos estacionamentos. Essa etapa destaca quais as ações foram previstas para a cidade, benefícios para os proprietários de imóveis em aderir e benefícios aos usuários do sistema de transporte. A segunda etapa consiste em explorar, dentro do que a lei propõe, o que a cidade já possui de infraestrutura para colocar a proposta em prática e o que falta ou pode ser melhorado. Para essa segunda etapa o Sistema de Informações Geográficas voltado para uso em transportes, Transcad versão 4.5, foi usado como ferramenta na produção de imagens e análises espaciais. Dessa forma foi possível verificar no Plano Diretor ações bastante interessantes no sentido de promover multimodalidade a partir do uso de estacionamentos. Pôde-se concluir que, apenas 7% dos estacionamentos com alvará ativo em Curitiba se enquadram nos parâmetros do que foi proposto na lei.
DIRETRIZES SOCIOAMBIENTAIS E SANITÁRIAS PARA REGULARIZAÇÃO FUNDIÁRIA URBANA EM UMA ÁREA NA AMAZÔNIA
Authors: Gonçalves Jéssica Corrêa , Filho Marco Antônio dos Santos Figueiredo , Brito Fábio Sergio Lima , Santos Myrian Silvana da Silva Cardoso Ataíde dos
Published: May 2024

O presente trabalho buscou levantar informações a respeito das diretrizes socioambientais e sanitárias para regularização fundiária em área de várzea, tendo como local de estudo as casas à margem do igarapé “Lago verde”, no bairro da Terra Firme em Belém – PA. Durante os meses de agosto a setembro de 2021 foram realizadas visitas in loco para coleta de informações das condições de habitabilidade dos moradores desta área, por meio de um check-list com as observações da real situação destas moradias e vivência dos residentes, além disso, aplicou-se questionários para se ter dados quali-quantitativos das questões que foram levantadas, as quais servem como subsídio para um estudo técnico ambiental do entorno do igarapé “Lago Verde”. Foi possível identificar os principais problemas relacionados a falta de saneamento básico e políticas públicas de regularização fundiária dentro da comunidade, podendo desta forma conhecer a realidade das mazelas nas áreas periféricas, tais como falta de água nas torneiras, resíduos sólidos descartados pelas ruas e no próprio igarapé “Lago verde”, assim como falta de pavimentação nas ruas, entre outras situações. Discutiu-se as leis, resoluções e normativas que trazem alternativas viáveis para as residências em áreas de preservação permanente (APP’S), como no caso do “Lago verde”.
CRESCIMENTO URBANO, TURISMO E IMPACTOS SOCIOAMBIENTAIS: AS CONTRADIÇÕES DE CAPITÓLIO
Authors: Silva Ana Carolina , Meireles Eduardo , Ribeiro Carvalho Rita de Cássia
Published: May 2024

Capitólio é uma pequena cidade mineira, muito influenciada pelos impactos sinérgicos e cumulativos associados à formação do Lago de Furnas e à conservação do Parque Nacional da Serra da Canastra. Suas belezas naturais atraem para milhares de turistas por ano, interessados sobretudo nas opções de turismo rural que o Mar de Minas oferece. Ao passo que o turismo representa grande parcela do PIB municipal e agrega grande parte dos postos de emprego na cidade, também implica em importantes impactos socioambientais. Esta pesquisa aborda as transições de uso do solo no município e o crescimento urbano desordenado, motivados pelo interesse econômico e exploração turística. Foram realizadas análises temporais comparativas de uso e cobertura do solo por meio de ferramentas de geoprocessamento. Verificou-se que a principal transição de cobertura do solo no município no período estudado foi a conversão de áreas florestais em agropecuária. A influência da atividade turísticas foi percebida na expansão urbana do município, com o crescimento de loteamentos irregulares e ocupação antrópica nas áreas próximas ao Lago de Furnas.
DIAGNÓSTICO DA MOBILIDADE URBANA INTELIGENTE NO MUNICÍPIO DE PORTO VELHO (RO)
Authors: Marques Raissa Coelho , Moraes Marcela Barbosa de , Oliveira Edson Aparecida de Araujo Querido
Published: May 2024

O objetivo deste artigo é identificar as dimensões de mobilidade urbana sob a ótica inteligente que são reconhecidas pelos habitantes da cidade de Porto Velho, Rondônia. Para alcançar o objetivo proposto foi realizada uma pesquisa do tipo survey de abordagem quantitativa. O instrumento utilizado para coleta de dados foi o questionário estruturado de questões fechadas com a amostragem da população que atingiu o nível de confiança de 95%, com 5% de erro amostral. Como procedimento metodológico foi realizado um tratamento de estatística descritiva. Por fim, conclui-se que o modelo tradicional de mobilidade urbana que hoje é o existente na cidade de Porto Velho/RO carece de investimentos e melhorias na infraestrutura no que tange a conservação de ruas e calçadas; há precariedade de acesso aos serviços de saúde e educação e não fora observada preocupação do poder público em propiciar fontes limpas de energia ou promover incentivos fiscais ao uso, pouca divulgação dos serviços prestados à população e por fim ineficiência de alguns programas municipais que não atendem à sua finalidade tal como Porto Velho Cidade Digital.
Para além do discurso técnico
Authors: Siqueira Reis Tiago
Published: May 2024

O artigo tem por objetivo compreender o projeto político nomeado de gerencialismo a partir da Reforma do Estado nos governos de Fernando Henrique Cardoso (1995-2002). Para tanto, analisaremos a documentação elaborada pelo Ministério da Administração Federal e Reforma do Estado (MARE), relacionando-a com trabalhos que dão sustentação teórica ao gerencialismo. Partindo da noção de Estado enquanto relação social, cujas políticas públicas resultam de disputas entre diferentes estratos sociais, confrontaremos o projeto gerencialista a fim de conhecer suas particularidades locais e em que medida apresenta formas de expropriação do aparelho do Estado. Pretende-se, desse modo, ampliar e oferecer elementos para o debate sobre o Estado e a edificação de políticas públicas, questionando a validade e essência teórica e prática gerencialista na esfera estatal, bem como de que forma estabelece condições para a existência de um Estado democrático e voltado para o fortalecimento de políticas sociais.
O SENAI como modelo para o ensino industrial:
Authors: Mendonça Cunha Adriana
Published: May 2024

Este artigo discute a relação entre o ensino industrial brasileiro e os programas de assistência técnica firmados entre Brasil e Estados Unidos no pós-Segunda Guerra. Para tanto, recorro às observações do pesquisador estadunidense Robert King Hall sobre o Serviço Nacional de Aprendizagem Industrial (SENAI) e a Comissão Brasileiro-Americana de Educação Industrial (CBAI). Hall era professor da Universidade de Columbia e atuou como consultor em vários países, a exemplo do Brasil e do Irã. Neste último, ele chegou a sugerir a adoção de escolas industriais seguindo o modelo do SENAI. A partir dos apontamentos de Hall, procuro demonstrar o papel preponderante assumido pelos programas de assistência técnica nos intercâmbios científicos e educacionais entre os dois país durante a Guerra Fria, destacando a importância destas trocas na promoção da circulação transnacional de modelos educacionais.
Configuração social da célula básica para exploração ilegal de ouro nas frentes de garimpagem da Terra Indígena Yanomami
Authors: Pereira Chagas Rodrigo , Crispim da Costa Ernildo
Published: May 2024

Este artigo apresenta a configuração social da célula básica de exploração ilegal de ouro aluvionar na Terra Indígena Yanomami. A partir das noções de configuração social de Norbert Elias e de campo social desenvolvida por Pierre Bourdieu, buscou-se criar uma ferramenta heurística que possa auxiliar na interpretação do fenômeno das frentes de garimpagem ilegais na Amazônia. Para isso, conduzimos práticas etnográficas e entrevistas abertas e semiestruturadas com agentes das frentes garimpagem ilegal.
Efficacy of yoga package on cognitive flexibility and attention in university girls: A single group pilot study
Authors: Tyagi Yashi , Singh Sandeep
Published: May 2024

Executive functions and attention are key indicator of cognitive health. Cognitive flexibility, the ability to flexibly switch between tasks, is a core dimension of executive functions. Yoga helps to improve mental wellness, which consequently provides cognitive flexibility.

This study aimed to determine the effect of yoga on cognitive flexibility and attention in university girls.

Thirty healthy university girls (group mean ± SD; 18.27 ± 1.44) were enrolled as participants in the study. Trail Making Test (TMT) parts A and B were used to assess their cognitive flexibility whereas sustained attention was determined using Six Letter Cancellation Test (SLCT). The assessments were taken at baseline and after three months of yogic practices. Statistical analysis was performed by paired t-test to examine the effect of yoga on cognitive flexibility and attention in university girls.

There was a significant decrease in time taken to complete TMT part A (t= 4.33; P<0.05) and a significant increase in total attempts (t= -2.75; P<0.05) and net attempts (t=-2.80; P<0.01) in six letter cancellation test after three months of yoga practice.

The results suggest that yoga improves visual search ability and motor speed skills and hence cognitive flexibility and attention in university girls.
Flipped classroom approach for trauma education: Attitudes of participants towards pre-course assignments before the advanced trauma life supports (ATLS) instructor course
Authors: Ray Amita , Misra Mahesh Chandra , Jain Vinod , Ghosh Sudip
Published: May 2024

A flipped classroom approach in principle, denotes pre-course engagement for an upcoming educational course. Although never used in trauma education, other educational literature is resplendent with the beneficial effects of pre-course engagement on the learning outcomes of the course itself. In this article we share the attitudes and perspectives of prospective Advanced Trauma Life Supports Instructors towards pre-course assignments to see whether this works in the field of trauma education.

After an online pre-course session, we administered a validated questionnaire to 100 participants. The questionnaire had 4 categories - the first dealing with participants’ characteristics and the rest with their attitude and perspectives towards the pre-course sessions. The last category included three open ended questions for qualitative analysis to explain the attitudes of the participants.

The participants showed a significantly positive attitude (p<0.029) towards this flipped classroom approach. The reasons cited were “effective sensitization”, “adequate feedback”, “peer learning” “user friendly platform” “enjoyable” and “relevance”. A significantly higher level of agreement with the questionnaire statements was seen amongst the private sector doctors as compared to those working in public sector medical colleges (p = 0.004). Same was observed amongst clinical specialists as compared to pre or para clinical specialists (p = 0.001). The Questionnaire had a Cronbach’s alpha of 0.86.

The study concludes that a flipped classroom approach can work well in trauma education. A tailored approach, depending upon participant characteristics, may be needed to enhance the relevance of a flipped classroom approach.
Differential Older Workers’ Experience with Technology-related Changes during the COVID-19 Pandemic
Authors: Poli Arianna , Heuer Annika , Motel-Klingebiel Andreas
Published: May 2024

Many workers, including older ones, experienced changes at work during the COVID-19 pandemic, among which was a sudden increase in the use of digital technologies. This paper aims at understanding older workers’ satisfaction with digital technology-related changes at work during the COVID-19 pandemic in the Nordics. Based on novel survey data collected in Sweden in 2020– 2021, we analyzed the experience with digital technology-related changes at work and modeled the (dis)satisfaction with such changes among older workers (aged 50+). Our findings show that groups of older, less educated, reporting concurrent workload changes and digital technology-related difficulties had an increased likelihood of being dissatisfied with digital technology-related changes at work during the COVID-19 pandemic. The results have implications for the theoretical understanding of late working life and for the redefinition of working life policies and age management strategies in times of work digitalization of work.
Multimodal meanings
Authors: Santos Maria Eduarda Sousa , Soares Barbosa Vânia
Published: May 2024

Visual compositions have been present in Western society since the beginning of civilization. They evolved due to technological advances and are nowadays more visual than ever with the use of images, colors, layout, and typography. The latter has gained the attention of theorists such as van Leeuwen (2006), Serafini and Clausen (2012) and Silva and Barbosa (2020). Its potential may be seen in picturebooks – a literary and multimodal material widely used in educational contexts (Serafini, 2014). Therefore, this research investigated the semiotic potential of typography in contemporary picturebooks in order to understand the possible meanings of its organization. Five picturebooks from the website Vooks were selected and three parts – the cover, pages of narration, and pages of mental and verbal processes – were analyzed. Then, their typography was described based on the categories proposed by van Leeuwen (2006) and Serafini and Clausen (2012). The results showed that typography has the potential of visually defining which participant is speaking as well as establishing relations with the meaning of the word. For example, the typography of “jumped” was organized as if the letters were jumping themselves. Thus, the emphasis on aspects such as weight, size, and framing may make readers aware that typography can express meanings that go beyond the verbal text.
Objeto Anafórico de Terceira Pessoa no Português Brasileiro
Authors: Teixeira de Sousa Lílian , Figueiredo Cristina , Lazzarini-Cyrino João Paulo
Published: May 2024

A realização do objeto direto anafórico no português brasileiro (PB) é um fenômeno variável, que pode apresentar um clítico acusativo, que está desaparecendo, o pronome pleno (PL) ou o objeto nulo (ON). Esse fenômeno tem sido analisado sob os pressupostos de perspectivas teóricas distintas: pela Sociolinguística (Omena, 1978; Duarte, 1986; Figueiredo; 2004), pela Teoria Gerativa (Raposo, 1986; Galves, 1988; Cyrino 1994, 1997) e pela Linguística Diacrônica (Cyrino, 1997; Macedo-Costa, 2012). Esses estudos apontam que a animacidade e a especificidade estão relacionadas à escolha das duas estratégias mais produzidas, ON e PL. Schwenter (2006, 2015), Cyrino (2017) propõem que a variação é devida à Marcação Diferencial de Objetos, justificando a emergência do PL. Creus e Menuzzi (2004) acrescentam que a falta de gênero semântico do antecedente favoreceria o objeto nulo. Considerando esses fatores, neste artigo, apresenta-se o resultado da investigação da variação entre o objeto nulo e o pronome pleno, na fala de indivíduos de três bairros de Salvador/Bahia. Como fatores extralinguísticos, fixamos: faixa etária, escolaridade e bairro. A análise de regressão logística mostrou objetos nulos como estratégia anafórica escolhida. A probabilidade de escolha do pronome pleno é verificada quando o antecedente é definido ou indefinido não-específico e quando ocorre entre moradores do bairro de Plataforma.
Use of Paper Ash and Lime as a Sustainable Stabilized Materials for Lateritic Soil
Authors: Omole Adekunle Isaac , Adegoke Oyekunle Pius , Adeowu Arafat Ayodeji , Sabit Musa Odunayo , Oluwadiya Yinka Benjamin , Fetuga Ibrahim Ademola
Published: May 2024

This research investigates the effectiveness of paper ash and lime for stabilizing lateritic soils in road construction applications. We assessed varying concentrations of paper ash and lime (0%, 3%, 6%, and 9%) to evaluate their effectiveness for soil stabilization. Initial analyses, including grain size distribution through wet sieving, specific gravity, moisture content, and Atterberg limits, were conducted to classify the soil. Following this, strength and compaction tests utilized standard proctor compactive energy, a method well-suited for field application. The findings indicated a general reduction in Atterberg limits (liquid limit, plastic limit, and plasticity index), an increase in maximum dry density (MDD), and a decrease in optimum moisture content (OMC) with increased concentrations of paper ash and lime. A thorough analysis of the results, along with a comparison to established standards, demonstrated significant improvements in soil properties. Specifically, the study found that 6% paper ash provided optimal stabilization, while 9% lime was effective as a stabilizing agent. These materials are suitable for use in the construction of subgrades and subbases for roads, aligning with AASHTO standards.
Perception of the general population on Epilepsy and Antiepileptic drugs: A questionnaire-based study
Authors: Arunnair Vijayamathy , Bhuvaneshwari S , Umamageswari M S , Vinotha A T Sathiya , Jeevithan S , Venkatesan Samuktha
Published: May 2024

The impact of epilepsy is multidimensional, ranging from socioeconomic to medical to psychological problems. The additional burden on quality of life is not only due to disease but also to the antiepileptic medication-related adverse effects. Though the majority of epileptics dwell in developing countries, studies have found a lack of knowledge, attitude, and practice towards epilepsy and its management, leading to a large treatment gap. This study aimed to assess the knowledge, attitude, and practice of epilepsy and antiepileptic medication among the general population, including epileptics or caregivers. A 6 month (August 2022 to February 2023) prospective, cross-sectional online questionnaire-based study utilizing Google Forms as a data collection tool was conducted among the general population at a tertiary care hospital in Coimbatore employing convenient sampling. Descriptive and inferential statistics (paired t-test, chi-square test) were used. The results were presented as numbers and percentages. The data obtained was analyzed using Statistical Package for the Social Sciences, version 27. We received 123 responses. 87.8% and 85.4% linked epilepsy to insanity and spiritual possession/trance, respectively. More than 90% opined that epilepsy was contagious, due to patient or ancestral sins, and treatable by faith healers. The mean knowledge, attitude, and practice scores (%) were found to be 78.04 ± 1.32, 71.23 ± 1.23, and 53.15 ± 1.38, respectively. Even though the urban population had satisfactory knowledge, the same was not translated into attitude and practice. There was a wide gap between knowledge, attitude, and practice. Considering the significant disparities in awareness, attitude, and practice even after decades in urban regions, policymakers and public health professionals must incorporate health education programs and healthcare services for the masses to bring about changes in a country like India. Keywords Knowledge, Attitude, Practice, Stigma, Quality of life, People living with epilepsy
National Park Service Internal Structures Toward Agency Resilience: A Mixed-Methods, Multi-Site, Mesoscale Investigation
Authors: Perry Elizabeth E. , Ginger Clare , Jewiss Jennifer , Krymkowski Daniel , Manning Robert E.
Published: May 2024

Agencies focused on protected areas’ conservation and recreation require internal capacity-building to enhance their organizational resilience (the ability to adapt and persist). Yet, internal capacity-building is often underemphasized as agencies attend to external relationships. This omission can lessen an agency’s ability to adapt to emergent stressors and opportunities. Specifically, relationships within an agency’s groups (i.e., divisions)—the intra-organizational mesoscale between individuals and whole organizations—can increase an agency’s ability to efficiently build resilience-enhancing adaptive capacity. The U.S. National Park Service (NPS) adopted this mesoscale in their Urban Agenda goal of One NPS, or building resilience-enhancing, agency-wide internal relationships. We investigated intra-organizational relationships in this context, examining relationships within (i.e., bonds) and across (i.e., bridges) three NPS groups: parks (physical spaces), programs (community outreach), and offices (administrative functions). Pairing qualitative interviews with quantitative social network analysis in Detroit, Tucson, and Boston, we examined internal relationship prevalence, supports, and opportunities. The NPS has program and office presence in each of these three urban areas but different proximities to national park units, which are the typical face of the NPS. Across these urban areas, we found that the parks group exhibits more bonds (park-to-park relationships), the programs group exhibits more bridges (program-to-park or program-to-office), and the offices group exhibits a mixture of bonds and bridges. To further One NPS and organizational resilience, cultivating bridges among the three groups is key. This investigation may inform a more strategic focusing of an agency’s limited resources. We highlight five directions for protected area managers’ consideration toward this aim: build bridges locally among groups; consider group composition when identifying divisions (i.e., programs appear more heterogeneous or dissimilar from each other than do the park and office groups); reflect on parks’ centrality to NPS identity and relationships; seek organizational structures supportive of relationship development; and focus on the organizational mesoscale for resilience-enhancing adaptive capacity. These directions for strategic focusing of organizational resources are based in the longstanding work of the NPS but ultimately transcend this single agency, providing targeted guidance for protected area agencies in building internal capacity toward external, public-oriented goals.
Pixelfed
Authors: Ploj Sara , Ogrizek Luka , Gangl Nina , Kumer Gal
Published: May 2024

Prispevek je analiza in opis decentraliziranega družbenega medija Pixelfed, vključuje informacije o njegovem nastanku in razvoju vse do danes. Pixelfed je decentralizirana alternativa Instagram-u, kar pomeni, da osnovne funkcije sovpadajo, prav tako pa sta si platformi zelo različni. Za razliko od Instagram-a je Pixelfed bolj uporabniško prijateljski (user-friendly), saj uporabnikom omogoča večjo zasebnost in kontrolo nad svojo deljeno vsebino in podatki, zato pa ni tako dobičkonosna. Medij gradi veliko metrik, kot so všečki, komentarji, najpomembnejši cilji povezav ter stopnja in čas odzivnosti, ki nam povedo priljubljenost, uporabnost in učinkovitost delovanja platforme. Platformo sestavlja veliko raznih instanc (strežniki), ampak na žalost še slovenska instanca ne obstaja, nam najbližja je italijanska. Instance prav tako niso razdeljene po tematiki, kar pomeni, da lahko v vsakem najdemo več raznih tematik.
Zapper
Authors: Košir Ana , Molnar Anja , Zorko Zala , Porić Ajla
Published: May 2024

Zapper je decentraliziran družben medij spleta 3.0, ki daje poudarek decentraliziranim financam, t. i. DeFi, verigam blokov nezamenljivih žetonov, t. i. NFT in decentralizirani avtonomni organizaciji oz. DAO. Uporabniki Zapperja lahko z DeFi sredstvi upravljajo, kar preko platforme same, potrebujejo le povezavo denarnic in ustvarjen profil. Za sliko lahko uporabijo personaliziran avatar ali NFT. Tako si uporabniki zgradijo lasten Zapper portfolio ter spremljajo svojo pot in sledijo drugim uporabnikom Zapperja. Ti lahko trgujejo z nezamenljivimi žetoni in jih izmenjujejo s kripto valuto Ethereum, ki je na Zapperju najbolj popularna, kljub temu pa so podprte tudi druge platforme in njihova sredstva. Uspešne naložbe in transakcije uporabnikov so vidne na profilu, kar pa uporabnikom pomaga pri pridobivanju sledilcev in posledično tudi na slovesu. Čeprav je portfolio viden vsem na mediju, ta nikoli ne razkriva osebnih podatkov, saj gre za decentraliziran družbeni medij. Zapper uporabnikom poleg možnosti sledenja drug drugemu, omogoča tudi povezovanje z ostalimi uporabniki, bodisi preko verižnega klepeta, t. i. Chainchat, ali preko zamenjave žetonov, t. i. swaps, med ostalimi uporabniki. Zapper velja za enega najbolj perspektivnih, v zadnjih mesecih je število ogledov naraslo za več kot milijon. Poglavje podrobneje predstavljena sistematično analizo decentraliziranih družbenih medijev, s poudarkom na Zapperju.
A Performance Analysis of a Two Way Stop Control (TWSC) Intersection under Mixed Traffic Conditions
Authors: Odesanya Joseph Femi
Published: May 2024

Intersections are road traffic infrastructure on highways installed to help settle directional movement that could result in conflict while vehicular trips are made. Evaluation of the challenges faced by different automobile users at the Araromi junction (A three Leg at-grade Intersection) located in Akure is the main objective of this paper. To achieve this objective, traffic flow data were collected on the spot by video recording and then the data were manually counted. While, the highway Capacity manual 2010 methodology was adopted to analyse The entry flow rates, Potential Capacities, Movement Capacities, Movement Control Delay, Approach Intersection Control and 95th Percentile Quene Length of the intersection. Findings shows that an average entry flow rate of 357 pc/h occurs for all the legs of the intersection, the North bound left turning movement of the intersection was not within the allowable limit, the average potential capacity by lane for the intersection is 445 pc/h, and the average movement capacity by lane 473 Pc/h, the various legs of the intersection has a level of service of ‘A’ and ‘C’ except the left turning minor street movement that has an ‘F’ LOS. Due to the influence of high traffic flow around the intersection, the analysis of the real-time traffic flow results reveals the need to diverge the high right turning movement into other route to cater for low left turning movement causing delay and poor LOS and a need to introduce Signal on the intersection in other to improve on her functionality.
The Company Share Prices in Indonesia During the Covid-19 Pandemic
Authors: Haryanto Rudy , Alvi Nur Hidayati  , Azline Alisa Ahmad
Published: May 2024

The Covid-19 pandemic in 2019 to 2021 affected world economic conditions, including inflation, currency exchange rates and world gold prices. This situation changed the direction of investment from the real sector to investing in gold and stocks. This study analyzed the variables of inflation, the rupiah exchange rates, the price of gold on the share prices of PT ANTM, Tbk. The approach used causalistic quantitative by processing secondary data in the form of monthly report data that had been published on the official website. The population and sample were 36 samples of monthly reports obtained by total sampling technique. To test and analyze the hypothesis SPSS version 20 was used. The results of the study: first, inflation has a significant effect on share prices, with a significance value of 0.030.; second, the price of gold has no effect and is not significant on stock prices, with a significance value of 0.422; third, the exchange rate has no effect and is not significant on stock prices, with a significance value of 0.093; fourth, inflation, gold price and exchange rate variables simultaneously have a significant effect on share prices, with a significance value of 0.002. 0.05). Investors were interested in investing in Mining Company shares during the Covid-19 pandemic. This investment decision was regardless of Indonesia's economic situation at the time of Covid-19 which was completely uncertain, especially in investment.
The Role of Internal Audit in The Merger and Acquisition Process to Provide Added Value: A Critical Review
Authors: Yuwono Matias Andika , Ellitan Lena
Published: May 2024

Purpose – This research focuses on how internal audit influences added value in the merger and acquisition (M&A) process. One of the internal audits provides value added by doing due process diligence For M&A transactions. The failure rate in creating value for companies and shareholders through M&A is still relatively high. Factors contributing to such failures include cultural differences between organizations, overly optimistic decisions based on market assessments, overestimating synergies, and inappropriate technology assessments. In overcoming these risks, the role of internal audit becomes crucial. This research underscores how internal audits can aid in recognizing and addressing the risks linked to M&A, particularly during the strategy, feasibility assessment, and results integration implementation phases.
Methodology – This research uses descriptive qualitative analysis methods
Findings – Research demonstrates that internal audit plays a vital role in guaranteeing the seamless operation of the M&A process. Internal audits help identify the various risks involved in the M&A process, from market and financial risks to legal and cultural risks. In addition, internal audits also provide recommendations for improvements needed to ensure that the M&A process runs according to the company's plans and goals. Thus, the contribution of internal audit is significant in ensuring the success of every M&A transaction carried out by the company.
Originality – This article comprehensively discusses internal audit activities in the M&A process so the internal audit activity can add value to the company.
Impact of Goodwill on Financial Statements (Benefits and Distortions)
Authors: Sumarni Nini , Illahi Ilham , Harfandi
Published: May 2024

Artikel ini membahas implikasi goodwill terhadap laporan keuangan, dengan fokus pada manfaat dan distorsi. Goodwill, aset tidak berwujud yang timbul dari akuisisi di mana harga belinya melebihi nilai wajar aset yang dapat diidentifikasi, dapat memberikan dampak positif terhadap laporan keuangan perusahaan dengan meningkatkan kekayaan bersih atau ekuitas pemegang saham. Namun, di samping manfaatnya, goodwill juga menimbulkan kekhawatiran, terutama terkait keakuratan nilai yang dicatat. Penilaian goodwill sering kali bergantung pada estimasi dan asumsi, sehingga meningkatkan risiko ketidakakuratan dalam pengukurannya. Melalui tinjauan literatur kualitatif, penelitian ini mengungkapkan bahwa meskipun penyusutan goodwill dapat mendorong investor dan pemangku kepentingan untuk merevisi ekspektasi mereka terkait pendapatan dan arus kas di masa depan, namun hal ini juga dapat menyebabkan oportunisme manajerial, sehingga mengurangi keandalannya. Untuk memitigasi risiko tersebut, perusahaan dapat meningkatkan kualitas audit dan menerapkan praktik tata kelola perusahaan yang efektif. Pada akhirnya, penelitian ini memberikan wawasan yang berharga mengenai implikasi goodwill pada praktik pelaporan keuangan.
Urgensi Pembuatan Akta Kesaksian dan Akta Pernyataan Ahli Waris Oleh Notaris
Authors: Widyadhana Juristie , Kemalasari Putri , Fitriani Shania Anindya
Published: May 2024

In matters of inheritance, an individual requires evidence to prove that they are legitimate heirs of the deceased.The Deed of Inheritance Testimony and The Deed of Heirs' Statement are deeds that are used as the basis for creating a Deed of Information on Inheritance Rights. In this research, we will discuss the urgency of creating a Deed of Inheritance Testimony and a Deed of Heirs' Statement and what consequences will occur to the Notary if they do not make these two deeds. The research method in this research is normative juridical, namely research using library materials or secondary data. This data will be analyzed qualitatively so that it will produce analytical descriptive data. Based on the research, it was found that the Deed of Inheritance Testimony and the Deed of Heirs' Statement have an important role in growing the Notary's confidence when creating a Deed of Information on Inheritance Rights and as security for the Notary himself because they can be used as evidence when there are problems related to heirs. As a result of not creating these two deeds, there are no sanctions given, but it can put the notary's position and position at risk of being exposed to problems from the Deed of Information on Inheritance Rights that has been made.
KEYWORDS: Deed of Inheritance Testimony, Deed of Heirs' Statement, and Notary
Personal Hygiene as Scabies Factors Incidence in the Institute Rehabilitation Center of the Vagrants, Scrounger and Mental Disabilities in South Sumatra Region
Authors: Haniifa Rahmadita Zinda
Published: May 2024

Introduction: Scabies, caused by the mite Sarcoptes scabiei, is a highly contagious skin infestation. Poor personal hygiene often contributes to its prevalence. This study aims to identify specific aspects of personal hygiene that influence the incidence of scabies among residents of the Institute Rehabilitation Center of The Vagrants, Scroungers, and Individuals with Mental Disabilities in the South Sumatra Region. Methods: This observational-analytic study employed a case-control design. Data collection involved clinical records, observations, and questionnaire-based interviews. A total of 160 occupants, comprising 80 cases and 80 controls, were selected through simple random sampling. Data analysis utilized chi-square test and multiple logistic regression tests. Results and Discussion: Chi-square analysis revealed significant associations (p-value = 0.000) between scabies incidence and bathing habits, cleanliness of mattresses and bed linen, cleanliness of clothing, and open defecation behavior. Multiple logistic regression indicated that open defecation behavior (OR = 56.336; 95% CI = 17.281 – 158.500) was the primary personal hygiene factor influencing scabies incidence. Thus, maintaining proper open defecation practices is crucial for residents' hygiene and health. Conclusion: Poor personal hygiene practices, including inadequate bathing habits, unclean bedding, dirty clothing, and open defecation behavior, contribute to the occurrence of scabies. Effective education and counseling by healthcare professionals are essential for promoting better hygiene practices among residents.
Endovascular repair for acute aortic syndrome involving the descending aorta
Authors: Rinaldi Enrico , Mascia Daniele , Campesi Carlo , Pizzutilli Alessio Centi , Melissano Germano
Published: May 2024

This review paper delves into the acute aortic syndromes, with a particular focus on those affecting the descending thoracic aorta, including acute type B aortic dissection (aTBAD), intramural hematoma (IMH), penetrating aortic ulcer (PAU), blunt traumatic thoracic aortic injury (bTAI), and ruptured aneurysm of the descending thoracic aorta (rDTA). These conditions present with sudden-onset symptoms such as severe chest or back pain, necessitating immediate medical attention. While traditional open surgical repair was historically the mainstay of treatment, advancements in endovascular techniques have revolutionized management approaches. Endovascular treatment offers advantages such as reduced operative time, blood loss, and hospital stay, making it a safer option for high-risk patients. However, it is crucial to carefully evaluate patients for endovascular suitability, considering the potential complications and risks associated with these techniques. This paper aims to provide an updated overview of acute aortic syndromes involving the descending thoracic aorta, analyze available therapeutic options, and review contemporary treatment modalities, shedding light on the technical aspects and considerations guiding clinical decision-making in this complex and life-threatening scenario.
TOPOLOGY OF EFFICIENT USE OF ENERGY BY A CHARGING STATION FOR ELECTRIC VEHICLES
Authors: Nerubatskyi Volodymyr , Hordiienko Denys
Published: May 2024

Рrеsеnts thе rеsults of thе rеsеarch of sеmіconductor convеrtеrs of chargіng statіons for еlеctrіc vеhіclеs basеd on lіthіum-іon cеlls. Basіc еnеrgy paramеtеrs and chargе-dіschargе charactеrіstіcs of lіthіum-іon and lіthіum-іron-phosphatе battеrіеs arе gіvеn. Thе topology of thе proposеd chargіng statіon for еlеctrіc vеhіclеs basеd on actіvе rеctіfіеr cіrcuіts іs prеsеntеd. Thе paramеtеrs of thе substіtutіon cіrcuіts thе battеry compartmеnt of thе Tеsla S еlеctrіc vеhіclе arе dеscrіbеd. Thе mеthod of fast battеry chargіng wіth constant voltagе and constant currеnt іs dеscrіbеd, whіch provіdеs a grеatеr numbеr of battеry chargе-dіschargе cyclеs. A sіmulatіon modеl of thе proposеd chargіng statіon structurе wіth an automatіc control systеm іs prеsеntеd. Thе еffіcіеncy of thе proposеd chargіng statіon systеm was calculatеd for dіffеrеnt paramеtеrs of thе chargе currеnt and swіtchіng frеquеncy.
FORMALIZATION OF THE PROCEDURE FOR ASSESSING THE ELECTRIC SUPPLY EFFICIENCY IN WORKSHOP NETWORKS OF INDUSTRIAL ENTERPRISES
Authors: Popov Vladimir , Zabolotnyi Anatolii , Dyachenko Vera , Fedosha Denys , Prykhno Valeriia
Published: May 2024

There is defined that the efficiency of workshop power supply networks largely determines the efficiency of the power supply system of the industrial enterprise as a whole and is determined by minimizing the reduced costs, which have two components: capital investments and the cost of electricity losses in workshop networks. Calculating the reduced costs during a technical and economic comparison of options is a labor-intensive task, since there is a large variability in the choice of circuit design, the choice of cross-sections of the conductors of the supply and distribution workshop network, as well as taking into account the design features of the workshop network.
   The analysis of the characteristics of the efficiency factors of workshop power supply was carried out. The basic components of the effective functioning of the workshoppower supply circuit are identified, namely: discreteness of electrical equipment; its placement in the workshop; operating modes of current-using equipment (CUE); loading schedule; ratio of the cost of electricity and the unit cost of workshop network elements.
   There has been determined that in any workshop power supply scheme, the duration of switching CUE on the electric power supply (CUE with a constant and variable operating mode), as well as the shape of the load schedule, largely determines the efficiency of its operation.
   Obtained results of a numerical experiment, when performing design of workshop networks in the DIPROPROM design institution (Zaporozhye), showed the effectiveness (3-7%) in determining the operational characteristics of workshop networks in comparison with existing engineering methods.