bluuebunny/crossref_metadata_2025 huggingface dataset:
Review of up-to-date approaches for extinguishing oil and petroleum products
Authors:   National University of Civil Defence of Ukraine, Kharkiv, Ukraine, Shevchenko R. I. , Strelets V. M. ,   National University of Civil Defence of Ukraine, Kharkiv, Ukraine, Loboichenko V. M. ,   National University of Civil Defence of Ukraine, Kharkiv, Ukraine, Pruskyi A. V. ,   Institute of Public Administration and Research in Civil Protection, Kyiv, Ukraine, Myroshnyk O.N. ,   ChIFS named after the Heroes of Chernobyl, Cherkasy, Ukraine, Kamyshentsev G. V. ,   ASBGS of Ukraine, Kyiv, Ukraine
Published: January 2022

The paper provides a review of up-to-date approaches for extinguishing oil and petroleum products. The variability of extinguishing methods and fire extinguishing agents is noted. Fire extinguishing agents used in extinguishing petroleum products are considered in more detailed way, and their environmental characteristics are discussed. The ambiguity of using various foams for extinguishing the fire is shown. A new method for extinguishing oil and petroleum products, based on the acoustic effect, and the capabilities of acoustic fire extinguishers for preventing and eliminating the combustible hydrocarbon fires, and their identification are analyzed. The further development of known approaches and the simultaneous emergence of innovative methods for extinguishing oil and petroleum products are shown. Keywords: oil; petroleum products; extinguishing agent; environmental characteristics; extinguishing foam; acoustic method.
Monitoring of technological environments at petrochemical plants as a means of ensuring their safe operation
Authors:   Ufa State Petroleum Technological University, Ufa, Russia, Bahtizin R. N. , Zubin S. N. ,   Ufa State Petroleum Technological University, Ufa, Russia, Laptev A. B. ,   All-Russian Scientific Research Institute of Aviation Materials, Moscow, Russia, Laptev D. A. ,   Lomonosov Moscow State University, Moscow, Russia, Bugai D. E. ,   Ufa State Petroleum Technological University, Ufa, Russia, Golubev A. V. ,   Ufa State Petroleum Technological University, Ufa, Russia
Published: January 2022

The cooling recycled water of petrochemical enterprises is characterized by high corrosion activity, unstable composition and, due to the evaporation of water in cooling towers, a constant increase in the concentration of dissolved salts, suspended particles and organic pollutants. Some of the salts formed by divalent metal ions fall out in the form of deposits, and the water is satu-rated with chlorine, sulfate, phosphate, and carbonations and becomes corrosive. At the same time, the corrosion activity of reservoir water varies widely depending on the saturation of cer-tain ions and other ingredients. It is established that monitoring the composition of recycled water and determining the corrosion rate of equipment and pipelines, carried out within 1-2 months, allow us to build a regression model of the dependence of the corrosion rate on the technical parameters of water, with which we can accurately calculate the values of the corrosion rate on the evaporation coefficient. Monitoring of technological environments and optimization of their composition through mathematical modeling will significantly improve the safety of equipment and pipelines operation at oil refining enterprises. Keywords: corrosion inhibitor; scale inhibitor; biocide; water circulation system; evaporation coefficient; monitoring; cooling water; regression model.
About the effectiveness of hydrocarbon diluents for pipeline transportation of high viscosity heavy and waxy oil
Authors:   Ufa State Petroleum Technological University, Ufa, Russia, Revel-Muroz P. A. , Bakhtizin R. N. ,   Ufa State Petroleum Technological University, Ufa, Russia, Karimov R. M. ,   Ufa State Petroleum Technological University, Ufa, Russia, Mastobaev B. N. ,   Ufa State Petroleum Technological University, Ufa, Russia
Published: January 2022

Deposits of tight high viscosity heavy and waxy oil are becoming increasingly important in the world economy. They are also of particular importance in Russia, where the fields of easy accessible oil are practically depleted, and the newly discovered ones are located mainly in the northern latitudes of the country, which complicates their delivery to places of consumption, and use of so-called "special methods" (heating, chemical reagents) leadsytanb to an increase Cost. Despite the abundance of such methods, one can distinguish one of the most accessible and understandable from the point of view of the physico-chemical effect - dilution with hydrocarbon diluents, as can be effectively used by adding ready-made motor fuels and light distillates of oil, as well as - cheaper stable gas condensate, also co-produced in oil fields.In the present work, the experience of blending high viscosity heavy and congealing waxy oil with various types of hydrocarbon diluents has been considered with the aim of improving the operational properties of hydrocarbon crude, the transport and processing of which are associated with high costs due to the peculiarities of the composition and properties of the oil. The results of laboratory experiments on dilution of heavy and congealing oils with diesel fuel and stable gas condensate are given, on the basis of which recommendations on the effective usage these special methods. Keywords: oil; rheology; effective viscosity; pour point; hydrocarbon diluent; stable gas condensate.
The Commentary of City Promotional Films Based on Transitivity Theory: A Case Study of Xi’an and San Francisco
Authors: Weng Yihan
Published: January 2022

Based on Halliday’s theory of ideational function, this paper selects the commentary of city promotional films of Xi’an and San Francisco and analyzes them from the perspective of the transitivity system. The main purpose of this paper is to analyze the language skills of the two commentaries and to provide ideas and methods for the audience to understand such explanatory texts. This paper focuses on the following two questions: 1) How do the six processes of the transitivity system distribute in the two commentaries? 2) What are the specific functions of the six processes in the two commentaries? The results show that 1) there are two kinds of processes frequently used in explanatory texts, namely material process and relational process; 2) the frequency of mental, verbal and existential processes is relatively low; 3) behavioral process has no occurrence. The reason may be that although the textual structure and description focus of the two commentaries are different, they both belong to the applied style of oral explanation, so that they share the same social functions of shaping the city image, highlighting the city connotation and managing the city brand.
Mindful Sustainable Consumption and Sustainability Chatbots in Fast Fashion Retailing During and After the COVID-19 Pandemic
Authors: Prete Marzia Del
Published: January 2022

The COVID-19 pandemic and ecological crisis are paving the way for new consumption models based on customers’ conscious choices and the subsequent integration of sustainable policies into retailers’ business strategies. As a consequence, the current consumer trends suggest that more people are becoming aware of their consumption standards and their repercussion on the environment and society. Statistics demonstrate that, in their purchasing processes, these “mindful customers” now search for a sustainable, self-sufficient way of living in harmony with nature. This paper argues that artificial intelligence (AI) is able to facilitate this process in the marketplace. More specifically, mindfulness with the support of AI technologies could be a plausible way to activate sustainable consumption patterns for avoiding overconsumption. The life-changing ability of mindful consumption is reviewed in this paper across domains of sustainability. Using a comprehensive literature review, the paper first outlines the theoretical and conceptual foundations of the mindful sustainable consumption (MSC) approach that fills the literature gap that almost always separates mindful consumption from sustainability. Second, the new conceptual approach is applied through a strategic framework in the field of fast fashion retailing through the use of AI-powered chatbots. In particular, the study defines a new category of chatbots, named sustainability chatbots (SC), which could convey mindful and sustainable consumption choices. The paper highlights that the MSC approach combined with the support of SC could enable marketing managers to create the appropriate context for embedding sustainability into consumer behaviour and fast fashion retailers’ strategies from a value co-creation perspective.
The Market and Investors Reactions to Mariana’s and Brumadinho’s Environmental Disasters: Sentimental or Rational Decisions?
Authors: Sancovschi Moacir , Silva Adolfo Henrique Coutinho e , Cosenza José Paulo
Published: January 2022

This research carried out event studies to analyze the reactions of the market and investors in Vale S.A. to the collapses of the Mariana and Brumadinho dams. It also assessed the extent to which the causes attributed to the market reactions to major disasters in previous research has helped to explain the reactions of the market and investors to the collapses of these dams. The analyses have shown that, in the case of the Fundão dam, there was a relevant reduction in the abnormal cumulative returns of common stocks and ADRs at the end of the eleven days of the collapse, despite the fact that the daily abnormal returns were not statistically significant. However, the abnormal trading volumes of these securities in the eleven days after the dam failure were generally negative and all statistically significant. In contrast, concerning the collapse of the Brumadinho dam, the abnormal returns on common stocks and ADRs were negative, relevant, and statistically significant, and, after the eleven days, the losses were considerable. The abnormal trading volumes of the securities were all positive and statistically significant, but the reactions of ADR investors were more intense than those of investors in common stocks. Examining the causal attributions made previously, there are indications that the market and investor reactions to the failures of the two dams were probably derived from the expectation that Vale and the other companies involved would incur severe losses and high contracting costs in political processes that would follow to the disasters, and from the difficulty the investors have had to assess the magnitude of these losses and costs.
Effect of 5'-fluoro-2'-deoxycytidine, 5-azacytidine, and 5-aza-2'–deoxycytidine on DNA Methyltransferase 1, CIP/KIP Family, and INK4a/ARF in Colon Cancer HCT-116 Cell Line
Authors: Sanaei Masumeh , Kavoosi Fraidoon
Published: January 2022

Background: Cyclin-dependent kinase inhibitors (CKIs) are the negative regulator of cell cycle progression, which inhibits cyclin-cdk complexes, resulting in cell cycle arrest. Recently, we evaluated the effect of 5-Aza-CdR on DNMT1 gene expression in the WCH-17 hepatocellular carcinoma (HCC) cell line. Objectives: The current study was designed to analyze the effects of 5-aza-2'–deoxycytidine (5-Aza-CdR, decitabine), 5-azacytidine (5-AzaC, vidaza), and 5'-fluoro-2'-deoxycytidine (FdCyd) on INK4a/ARF, CIP/KIP, and DNA methyltransferase 1 gene expression, apoptosis induction, and cell growth inhibition in colon cancer HCT-116 cell line. Methods: The colon cancer HCT-116 cell line was treated with 5-azaC, 5-Aza-CdR, and FdCyd at 24 and 48h. To determine colon cancer HCT-116 cell viability, cell apoptosis, and the relative expression level of the INK4a/ARF, CIP/KIP, and DNA methyltransferase 1 genes, MTT assay, flow cytometry, and qRT-PCR were done, respectively. Results: 5-azaC, 5-Aza-CdR, and FdCyd significantly inhibited colon cancer HCT-116 cell growth and induced apoptosis. Besides, they significantly increased CIP/KIP (p21CIP1, p27KIP1, and p57KIP2) and INK4 (p14ARF, p15INK4b, and p16INK4a) and decreased DNMT1 gene expression. Besides, minimal and maximal apoptosis were seen in the groups treated with FdCyd and 5-Aza-CdR, respectively. The IC50 for CAF for FdCyd was 1.72 ± 0.23 and 1.63 ± 0.21μM at 24 and 48h, respectively. The IC50 for CAF for 5-AzaC was 2.18 ± 0.33 and 1.98 ± 0.29 μM at 24 and 48h, respectively. The IC50 for CAF for 5-Aza-CdR was 4.08 ± 0.61 and 3.18 ± 0.50 μM at 24 and 48h, respectively. Conclusions: The 5-azac, 5-Aza-CdR, and FdCyd can reactivate the INK4a/ARF and CIP/KIP families through inhibition of DNMT1 activity.
Evaluating the Risk Factors of Development and Progression of Diabetic Retinopathy: A Review Study
Authors: Rasoulinejad Seyed Ahmad
Published: January 2022

: Diabetes is a chronic, underlying, and common disease worldwide that imposes an enormous burden on the health system. Diabetic retinopathy (DR) is a serious complication in the eye caused by diabetes and may lead to visual impairment and blindness. The knowledge about the risk factors of DR is critical for the prevention of disease and developing treatment options. Moreover, DR is a multifactorial disease, and many studies have demonstrated various risk factors associated with it, such as hyperglycemia, hypertension, hyperlipidemia, etc. In this review study, we survey the main risk factors of the development and progression of DR.
Child Euthanasia and the Church
Authors: Pirog Thomas ,   The National Catholic Bioethics Center
Published: January 2022

The creeping expansion of euthanasia around the world, but especially in the West, is a concern for any moral theologian. This expansion has already reached beyond the elderly into younger and objectively healthier groups, including children. The stance of the Catholic Church is that euthanasia is never permissible and must combat philosophies and laws that support it as fervently as possible.
Reflections on Revising Part 3 of the ERDs
Authors: Brehany John F. ,   The National Catholic Bioethics Center
Published: January 2022

This article is fourth in a series on the Ethical and Religious Directives, examining their formation, structure, and potential revisions to the directives. Part three, “The Professional—Patient Relationship,” is the focus of this installment. It covers directives specific to caring for individuals, as well as new issues that have arisen since the last major revision of the directives. This article gives valuable insight on both the past and potential future of the ERDs.
Modifying Clinical Ethics Cases for Pedagogy: The Case of “Enzokuhle”
Authors: Murphy Michael J. ,   Philosophy Documentation Center
Published: January 2022

In order to effectively prepare students for medical decisions with complex, ethical disagreements and value-laden conflicts, a progression from simpler case analysis to multi-layered conflicts is often helpful. Presented here is a unique case of pregnancy in a true hermaphrodite from recent medical literature. The case is artificially layered with additional, medical and discoverable contextual issues to help analyze three distinct questions in medical ethics: 1) Is it ethically permissible to perform an elective termination of pregnancy (ETOP) on a minor, 2) Is it ethically permissible to keep this information from the parents, and 3) are additional and complicating medical features included in confidentiality agreements involving minors? The pedagogical goals include introducing and effectively utilizing the Orr-Shelton, four box method of clinical ethics assessment, demonstrating the need to uncover/discover important contextual (cultural, religious, family, etc.) features not usually incorporated fully into patient charts, to prepare medical students to research and become familiar with the local legal environment, and to illustrate that what appears to be a single a single ethical dilemma is likely far more complex requiring a multi-focused assessment.
Not “Minority” but “Minoritized”
Authors: Wingrove-Haugland Erik , McLeod Jillian ,   Philosophy Documentation Center
Published: January 2022

Rather than referring to “minorities,” “members of minority groups” or “underrepresented minorities,” we should refer to such individuals as “minoritized.” Using “minoritized” makes it clear that being minoritized is about power and equity not numbers, connects racial oppression to the oppression of women, and gives us an easy way to conceive of intersectionality as being a minoritized member of a minoritized group. The term “minoritized” reveals the fact that white males and other dominant groups minoritize members of subordinated groups rather than obscuring this agency, describes microaggressions better than the term ‘microaggressions,’ and helps explain the need for solidarity within minoritized groups. It gives us a powerful way to promote racial justice by appealing to the common experience of being excluded. While using “minoritized” risks creating a false equivalence that sees all instances of being minoritized as equal and discounting unique forms of oppression by subsuming them under a single term, using this term carefully can ensure that its advantages outweigh these risks.
Partidos conectivos durante la pandemia. La estrategia de comunicación de Podemos en Twitter
Authors: De Marco Stefano , Guevara Gil Juan Antonio , Martínez Torralba Ángela , García-Ceca Sánchez Celia , Echániz Jiménez Alejandro , Palese Rosario
Published: January 2022

Desde el punto de vista comunicativo, los partidos conectivos se definen por su inclinación hacia modelos participativos donde los flujos conversacionales posean una estructura horizontal y bidireccional entre la élite de la formación y el activismo de base. Esto es posible gracias a que ceden parte de su organización a herramientas de la Web. Dentro de esta taxonomía se encuentra el partido español Unidas-Podemos como ejemplo de partido conectivo. En esta investigación se analiza la vertiente comunicativa externa, basada en el uso de redes sociales online, de los principales partidos políticos españoles durante el periodo de Estado de Alarma provocado por el COVID-19. Para ello, se observará la tasa de interacción y respuestas en Twitter de los representantes del Congreso de los Diputados. Los resultados muestran que los patrones comunicativos a nivel externo de Unidas-Podemos responden a criterios verticales, propios de los partidos convencionales.
From a communicational point of view, connective parties are based on horizontal and bidirectional structure of conversational flows between the elite of the formation and the party activists. This is possible because they delegate part of their organization to digital and online platforms. In this paper we use the Spanish party Unidas-Podemos as a case of study of connective parties. Drawing upon the Twitter response and interaction rate between Spanish representatives and citizens, this research analyzes the external communicative aspect of the main Spanish political parties during the Lockdown caused by COVID-19. The results show that the external communication patterns of Unidas-Podemos respond to vertical criteria, typical of conventional parties.
Lo necesario, lo superfluo y la medición de la pobreza
Authors: Larrú José María
Published: January 2022

El objetivo de este trabajo es unir la aportación de la filosofía escolástica con la técnica de la medición de la pobreza a fin de clarificar cuánto ingreso debe ser normativamente considerado para adquirir “lo necesario” para vivir. La escolástica ha diferenciado –desde Tomás de Aquino- los bienes necesarios, los socialmente necesarios y los superfluos. Sobre los dos primeros se reconocieron derechos de propiedad usufructuaria, pero no sobre los superfluos. Lo que el trabajo investiga es saber si la línea de pobreza absoluta, nacional o internacional (actualmente establecida en $1,90 diarios en PPP de 2011) da buena cuenta de la capacidad para adquirir “lo necesario”. Rechazada esta opción se propone un Índice de Acceso a lo Necesario y se analizan las consecuencias de políticas públicas que conlleva la ambigüedad de “lo necesario”.
The goal of this work is to combine the contribution of scholastic philosophy with the technique of poverty measurement in order to clarify how much income should be normatively considered in order to acquire "what is necessary" to live. Scholasticism has differentiated - from Thomas Aquinas - the necessary, socially necessary and superfluous goods. On the first two rights of usufruct property were recognized, but not on the superfluous ones. What the research investigates is whether the absolute poverty line, national or international (currently set at $ 1.90 per day in PPP 2011) gives a good account of the capability to acquire "what is necessary". Once this option is rejected, an Index of Access to the Necessary is proposed and the consequences of public policies that entail the ambiguity of "what is necessary" are analyzed.
The Construction of A Sheep Acute Respiratory Distress Syndrome Model Induced by Smoke Inhalation Injury
Authors: YU Fei , TAN Yuan-fei , SHENG Guan-nan , CHEN Guan-nan , WANG Nan-nan , GONG Ting , QU Bo
Published: January 2022

Objective To establish a model of acute respiratory distress syndrome induced by sheep smoke inhalation lung injury. Methods Nine healthy, 12-24 month old, non-pregnant female sheep were randomly selected, the sheep were divided into three groups, through the internal control of smoke generator device components (CO, CO2, O2, particle concentration and smoke temperature, etc.) to adjust the exposure time of the sheep model construction of smoke. The chest CT were examined before and after exposure to smoke at 6h, 12h, 24h and 48h, respectively. From the smoke exposure 12h endotracheal intubation and mechanical ventilation, by adjusting the ventilator parameters of hypoxemia and hypercapnia, statistical analysis of PaO2/FiO2, PEEP and other indicators, according to the ARDS definition of diagnosis in Berlin definition. Results The CT showed mild inflammation of the lungs in first group, oxygen index of 95% confidence interval [331.13, 353.53]; In second groups, oxygenation index 95% confidence interval [220.09, 383.90]; CT showed airway edema, pulmonary inflammatory exudation and lung injury in third group. Oxygenation index 95% confidence interval of [195.16, 244.84], PEEP>5cm. There was significant difference between the two groups (P<0.05). Conclusions The severity of lung injury can be changed by adjusting the exposure time of smoke inhalation; when the smoke exposure time up to 45 minutes, a stable model of smoke inhalation lung injury in sheep ARDS can be successfully established.
1,8-Cineol Attenuated AΒ25-35-Induced PC12 Cell Injury through Reducing Caspase 3 Expression and NO Production
Authors: Zhang Ze-qin , Li Hai-jian , Li Wan-zhong , Wang Lin , Li Zhen-zhen , Zhao Chun-zhen
Published: January 2022

Objective To investigate the effect of 1,8-cineol on caspase 3 expression and NO production induced by Aβ25-35 in PC12 cells. Methods PC12 cells were cultured in vitro, and cell injury was induced by Aβ25-35 with a concentration of 20 μM. 1,8-cineol (1, 3, 10 μM) was pretreated before Aβ25-35 treatment. PC12 cell viability was evaluated by MTT detection assay. Caspase 3 protein expression was detected by Western blotting. The level of NO production in PC12 cells was measured using ELISA detection assay kit. Results In cultured PC12 cells in vitro, MTT results showed that 20 μM of Aβ25-35 reduced cell viability significantly compared with control group. The cell viability was increased by pretreatment with 1,8-cineol with concentrations of 3 and 10 μM compared with Aβ25-35 only group. Western blotting results showed compared with control group, caspase 3 expression was increased significantly in 20 μM Aβ25-35 group. Compared with Aβ25-35 group, 1,8-cineol of 3 and 10 μM group reduced caspase 3 protein expression significantly. The level of NO production in PC12 cells was increased significantly, which was decreased by pretreatment with 3 and 10 μM of 1,8-cineol. Conclusions: Our results revealed a protective effect of 1,8-cineol on Aβ25-35 induced PC12 cell injury through inhibition of caspase 3 expression and NO production.
Observation of Postoperative Analgesia in Elderly Patients with PFNA By Routine Pulsed Lumbar Plexus Administration
Authors: Song Zhi-yong , Wang Qi
Published: January 2022

Objective to observe the postoperative analgesia of elderly patients with PFNA by pulsed lumbar plexus administration. Methods: 90 patients with PFNA postoperative analgesia were selected and divided into three groups on average. The first group, 30 routine PCIA. The second group received PCEA analgesia after spinal anesthesia. In the third group, the intraoperative lumbar plexus nerve block was completed and the anesthetic catheter was indwelling. The drug administration mode was programmed pulse administration without background dose. The pain index, movement tissue index and the incidence of various adverse reactions were observed after PFNA. Results the pain score of peripheral nerve block program pulse group was significantly lower than that of general anesthesia group, the incidence of motor tissue was lower than that of epidural group, and the incidence of side effects was lower than that of general anesthesia group and epidural group. Conclusion patients with PFNA is mostly elderly patients with varying degrees of system disease and organ function degradation, extra week nerve block program pulse to VAS score is lower and less motor block, fewer side effects, is PFNA more effective postoperative analgesia mode, you can reply as soon as possible to the patient's activity ability, improve the prognosis of patients.
Precise Application of the Xiao-Chai-Hu-Tang in 98 Cases of Patients with the Major Syndrome of Feeling Pain and Tenderness under the Right Costal Arch
Authors: Wang Zhi-qiang , Song Zhi-yong , Yang Bai-zhi , Wang Xiu-hong , Gui Huan-chen , Gao Zhao-wang
Published: January 2022

Xiao-Chai-Hu-Tang (XCHT), a representative of previous edition of Formulas of Traditional Chinese Medicine and harmonizing formulas, has multiple pharmacological functions. However, a variety of side effects could be caused by misuse or abuse, ignoring the theory of diagnosis and treatment based on the combination of syndrome and disease differentiation. Therefore, we conducted a retrospective study to evaluate the efficacy of XCHT, depending upon the individual patient’s condition. Among 98 patients treated with XCHT, most of the patients of syndromes could be cured after about two course. The therapeutic effect rate of prescribed XCHT in our 98 cases of treatment is 91.84% (90/98). In addition, the high frequently syndromes are consistent with Shanhanlun. With multiple years of experience, we believe that: patient feel pain and tenderness under the right costal arch is one of the symptoms of patients who fit for the treatment with XCHT.
Discussion on the Valuable application of Healthy Education Nursing Care before Ultrasound Examination
Authors: Zhu Xi-li
Published: January 2022

Objective To analyze the effect of health education on the nursing care for ophthalmic trauma patients. Methods Our hospital randomly selected 80 patients who underwent ultrasound examination from September 2017 to September 2018. According to the patients' consultation sequence numbers, they were divided into control group and observation group, with 40 cases per group. The patients in control group were only given ultrasound examination and routine guidance. The patients in observation group were given health education nursing care before ultrasound examination. The ultrasound examination time, anxiety and depression, as well as compliance of examination, health knowledge and nursing satisfaction were compared between the two groups. Result Compared with the data of the patients in the control group, the anxiety and depression of the patients in the observation group were significantly improved after health education. In the observation, the patients' mastery of health knowledge, compliance of examination and examination nursing satisfaction were all higher and the ultrasound examination time was shorter than that in the control group. The difference between the two groups was statistically significant (P < 0.05). Conclusion Healthy education nursing care can effectively improve the anxiety and depression of patients undergoing ultrasound examination, enhance the compliance of patients and shorten the ultrasound examination time, making the quality of clinical ultrasound examination recognized and satisfied by patients.
Discussion on the Phenomenon of Irrational Clinical Drug Use and Improvement Measures
Authors: Liu Jing-wen
Published: January 2022

Objective To discuss the irrational drug use in clinic and its improvement measures. Methods To select 132 prescriptions of Western medicine from the pharmacy department of our hospital as the research object, prescribed from July 2017 to September 2018. According to the prescription time, the safety and irrational use of drugs were observed according to the principle of clinical rational use of drugs. They were divided into experimental group and control group, in which the control group did not include the improvement measures, the experimental group included the improvement measures and each group had sixty-six prescriptions. Results The incidence of repeated drug use, improper drug use combination, improper use of antibiotics, the abuse of antibiotics and other irrational drug uses in the experiment was lower than that in the control group and there was significant difference between the two groups (P < 0.05). Conclusion In the clinical drugs administration of Western medicine, it is necessary to strengthen the observation of irrational drug use and give timely improvement measures to ensure the safety of clinical drugs.
Research on Stroke Rehabilitation Nursing Mode with Senior Nurses as Bond
Authors: He Xiao-hong , Wang Ping , Rui Zu-qin , Zhang Xiang-li , Ma Wen-yun , Lu Min
Published: January 2022

Objective To explore the effect of rehabilitation nursing model for stroke patients with senior nurses. Methods From October 2017 to October 2018, 46 stroke patients with hemiplegia in community hospitals were selected. 23 stroke patients in community who were willing to accept rehabilitation nursing service package were included in the observation group. The elderly nurses in sinking community were the leading nurses in rehabilitation nursing and home rehabilitation nursing guidance. Community stroke patients without rehabilitation nursing package were selected as control group. Community nurses were the leading nurses in rehabilitation nursing and home-based rehabilitation nursing. The incidence of pressure sores, aspiration rate, accuracy rate of anti-spasm posture placement, and mastery rate of intermittent catheterization technique were compared between the two groups. Results After the intervention, the incidence of pressure ulcer and aspiration rate in the observation group were significantly lower than those in the control group (P < 0.05). The accuracy of anti-spasm posture placement and the mastery rate of intermittent catheterization were significantly higher in the observation group than in the control group (P < 0.05). Conclusion Stroke rehabilitation nursing model with senior nurses as a link has certain effect on rehabilitation nursing of stroke patients in community by strengthening the training, learning and guidance of rehabilitation nursing knowledge and skills of community nurses. Nurses in community hospitals have strengthened two-way linkage, which is of research value, but they are now voluntarily selected in the community. The number of patients choosing rehabilitation care packages is still relatively small, the number of senior nurses in sinking communities is relatively small, and there is still a lot of work to be done to achieve real results. This is a long-term project, which requires time and experience precipitation. Key words Senior nurses; Link; Stroke; Rehabilitation nursing
An Analysis for the application of rapid rehabilitation surgery concept in the nursing satisfaction of the perioperative period of the elderly’s hip arthroplasty
Authors: Shi Hua-ping
Published: January 2022

Objective To explore the application of rapid rehabilitation surgery concept in the nursing satisfaction of the perioperative period of the elderly’s hip arthroplasty. Methods To select 58 cases of elderly patients undergoing hip arthroplasty in our hospital from March 2017 to February 2018 as the research subjects. The patients were randomly divided into the experimental group and the control group by number table method and there were 29 cases per group. The patients in the experimental group were in the nurse of the concept model of rapid rehabilitation surgery, while the patients in the control group were in the routine nurse of perioperative period. Results After the comparison of hip joint function recovery score, operation time and hospitalization time between the two groups of patients, the advantages of hip function recovery score, operation time, and hospitalization time in the experimental group were obvious statistically significant(P 0.05). Compared with the patients in the control group, the nursing satisfaction of the patients in the experimental group was higher and statistically significant(P 0.05). Conclusion The concept of rapid rehabilitation surgery is effective for the elderly patients with hip arthroplasty, which can promote the rehabilitation of patients and improve the nursing satisfaction of patients. It is of great significance to improve the relationship between nursing patients.
Development and current status of treatment for pediatric indirect inguinal hernia
Authors: Mo Zhifeng , Tan Yuanfei , He Hanzhong , Zhang Zhuorong , Yang Wenbin
Published: January 2022

To investigate the development and current status of the treatment of pediatric indirect inguinal hernia. Inguinal hernias include indirect hernias and direct inguinal hernias, but there are almost indirect inguinal hernias in children . Pediatric indirect inguinal hernia that the most common disease in pediatric surgery is almost caused by patent processus vaginali which incidence ranges from 0.8% to 4.4%.The treatment of pediatric indirect inguinal hernia reflects the process of pediatric surgery development, which from conservative non-surgical treatment to high ligation of the longitudinal incision hernia sac. In recent years, with the continuous improvement of medical level in China, laparoscopic technique has been applied in hospitals all over China, and laparoscopic high ligation of indirect inguinal hernia sac has become the standard for the treatment of pediatric indirect inguinal hernia.
Advances in the application of respiratory training in patients with cardiovascular disease
Authors: Ye Yumei , Gong Beitao , Hu Yaoyao
Published: January 2022

As one of the lifestyle interventions, respiratory training has a positive role in rehabilitation. This study summarizes the mechanism, intervention technique, effects and problems of respiratory training in patients with cardiovascular disease, so as to provide reference for the developing of the best respiratory training program of the clinicians.
To investigate and analyze the current using situation of nasointestinal tube in emergency department of 126 general hospitals in Guangdong province
Authors: Huang Xuanjie , Deng Lisi , Nie Fali , Zhang Zhiming , Zhou Hao
Published: January 2022

Objective To analyze the status and cognition of nasointestinal tube in emergency department of 126 general hospitals in Guangdong province. Methods The self-designed general information questionnaire for knowledge, belief and behavior was used to investigate 602 emergency nurses of 126 general hospitals. Results 1. The cognitive score of emergency nurse on nasointestinal tube showed: The score of knowledge was (8.24 + 5.02), the qualified rate was 52.2%. the score of belief was (23.82 + 5.03), and the score of behavior was (29.77 + 18.71). Multiple linear regression results showed that，The emergency nurses' cognition of nasointestinal tube was influenced by Working age, professional ranks, level, educational background and hospital grade. （P＜0.01）2.Correlation analysis showed that the scores of attitude and behavior of nurses with different educational background, professional ranks and working age were significantly different. Conclusion Emergency nurse have a low cognition of nasointestinal tube in Guangdong Province. It is necessary to study the knowledge and technology of nasointestinal tube，make standardized operating guideline and procedure, to further improve the emergency nurses'essary to study the knowledge and technology of nasointestinal tube nificantly different.
Discuss the prevention and nursing strategies of clavicular fracture in newborn
Authors: Zhang Xiuqing , Hou Lili , Yuan Shengyan , Lu Huichan , Huang Xuanjie , Zhang Jianfang
Published: January 2022

Objective To summarize the reasons of clavicular fracture in newborn, discuss strategies on the prevention and nursing treatment . Methods Review and analyze etiopathogenisis of 23 cases with clavicular fracture in newborn from January 2017 to December 2019 in Dongguan People's Hospital (China) and discuss their nursing treatment methods. Results Causes of clavicular fracture in newborn are mostly due to shoulder dystocia and a small part of that result from the birth process anomalies or negligence of medical personnel. All children of clavicle fractures in newborn partially fixed affected limb, can reach clinical cure after six weeks. Conclusion Correctly assessing the fetal weight, selecting the appropriate mode of parturition, proper handling the birth process anomalies, and establishing a good sense of responsibility with medical personnel can reduce the incidence of clavicular fracture in newborn. Neonatal clavicular fracture after a short partial brake can completely heal without sequela.
Successful Non-surgical Management of Superior Mesenteric Artery Compression Syndrome: A Case Report
Authors: Huang Shaomin , Hu Youting , Huang Xuejie , Zhang Xuemei
Published: January 2022

In this study, we aimed to report a case of superior mesenteric artery syndrome, with a particular focus on the patient's non-surgical management including enteral nutrition therapy. The focus of this patient's care includes nasogastric tube management, parenteral and enteral nutrition care (personalized nutrition treatment plan), proper lying position, negative pressure drainage in the stomach, and psychiatric mental health nursing. This case study supports that with efforts focusing on patients’ nursing and enteral nutrition therapy, non-surgical management could be an effective approach in treating superior mesenteric artery compression syndrome.
The Effect of Nutrition Education on Nutrition Treatment of Chronic Kidney Disease
Authors: Lin Lian , Zhong Xiaochun , Huang Shaomin , Zhang Xuemei
Published: January 2022

Chronic kidney disease (CKD) is a common chronic disease in the clinic. Patients are often at the risk of malnutrition due to impaired renal function [1-3]. In order to reduce the risk of malnutrition, it is advocated to implement nutritional therapy for patients with chronic kidney disease, but some patients have poor compliance and irregular dietary behavior, so effective intervention means are needed. Nutritional education is a specialized nutritional intervention measure. In order to assess the application effect of nutritional education in the nutritional therapy of chronic kidney disease, a randomized control trial was conducted on 100 patients with chronic kidney disease who received nutritional therapy in our hospital from August 2020 to October 2020.
Effect of Xiaochaihu Decoction on Cytokines and MAO in Experimental Autoimmune Prostatitis Rats
Authors: Wang Zhiqiang , Zhu Liping , Mu Zhenyu , Wang Xiaogang
Published: January 2022

Objective To observe the effect of Xiaochaihu Decoction on cytokines and MAO in model rats with experimental autoimmune prostatitis (EAP) to provide an experimental basis for the use of Chinese herbal prescriptions in the treatment of chronic prostatitis. Methods Thirty male Wistar rats were randomly divided into blank Group, model group and treatment group (Xiaochaihu Decoction). Except the blank group, rats in model and treatment groups were injected subcutaneously in multiple points on days 0 and 30 with prostatic protein extractive solution (60 mg/mL), and intraperitoneally injected with diph-theria-pertussis and tetanus vaccine (DPT vaccine) to establish the EAP model. Model rats were administrated Xiaochaihu Decoction and were sacrificed after 4 weeks. Pathological changes in the prostate gland were observed with HE staining and changes in serum interleukin-6 (IL-6), interleukin-8 (IL-8), and Tumor necrosis factor-α (TNF-α) levels were detected with enzyme-linked immunosorbent assay (ELISA). Quantitative PCR to observe the expression of IL-17, CCL2 and MAOA/B. Results After treatment with Xiaochaihu Decoction, the serum IL-6, IL-8, and TNF-α levels all significantly lower in the treatment group as compared with the model group (P < 0.05). The intervention of Xiaochaihu Decoction can change the state of abnormally elevated IL-17, CCL2 and MAOA expression levels. Conclusions The therapeutic efficacy remarkable from the theory of heating into the sperm chamber to experimental autoimmune prostatitis rats.
The Temporal Profile of OPG Expression and Regulatory Role on Ischemic Brain Injury in Rats After MCAo
Authors: Li Haijian , Jincheng Jincheng , Wang Lin , Fu Yiting , Zhao Chunzhen
Published: January 2022

Objective To investigate the temporal profile of osteoprotegerin (OPG) in middle cerebral artery occlusion (MCAo) rats and the serum level of RANKL and ALP in OPG deficient and wild type rats. Methods Rats was anesthetized and subjected to MCAo by transient occlusion of middle cerebral artery occlusion. The serum level of OPG, RANKL and ALP in rats after MCAo was examined by ELISA assay. The protein expression of OPG in ischemic brain was determined by Western blot analysis. Results The level of OPG in the rat serum was significantly increased from 6 h after MCAo and peaked at 12-24 and 72-168 h. The protein expression of OPG was upregulated from 12 h after MCAo and peaked at 72 h. The level of RANKL and ALP was significantly decreased in OPG deficient rats after MCAo. Conclusion OPG/RANKL signaling is associated with brain injury after MCAo, indicating a potential therapeutic target for ischemic stroke.
A Survey on Specialty Competencies of Emergency Nurse Practitioners from 15 Tertiary General Hospitals in Guangdong Province
Authors: Huang Xuanjie , Luo Yumei , Wang Jiao , Huang Shaomin
Published: January 2022

Objective To understand the current situation of emergency nurses’ specialty competence and propose improvement strategies accordingly, aiming to provide a reference for the comprehensive enhancement of nurse competency as well as the selection and training of high-level nursing management talents. Methods Using a self-made questionnaire based on literature review, 266 emergency specialist nurses in 15 tertiary general hospitals in Guangdong Province were surveyed through the questionnaire star. Results The survey showed that the participants appeared to have a high level of self-confidence and recognition for most indicators, as suggested by a high score (195.46±23.64), except for the aspect of scientific research ability. The scores of scientific research ability items ranged from 3 to 15 points (the 50th quantile was 9 points), and the score was 10.41±2.28 with a median score of 10, indicating that clinical nurses lacked confidence in scientific research abilities. The results of linear regression analysis suggested that gender, job title, publications in recent 5 years, and whether directly affiliated to a teaching hospital were the influencing factors that affect the competence of emergency nurses. Conclusions Scientific research ability is the major shortcoming of emergency specialist nurses. The influencing factors that affect nurses’ competencies include gender, professional title, publications in recent 5 years and whether directly affiliated to a teaching hospital. Nursing scientific research is the power source of the continuous development of nursing discipline. Therefore, it is recommended that the leaders of healthcare authorities and hospitals should strengthen the training of nursing scientific research and improve the scientific research ability of nurses.
To analyze the clinical characteristics of emergency syncope patients and explore their clinical treatment strategies
Authors: XIE Chuyu , ZHANG Hujie , HUANG Xuanjie , HUANG Jianmao , MO Zhifeng
Published: January 2022

Objective To analyze the clinical characteristics of emergency syncope patients and explore the strategies in their clinical treatment. Methods Eighty-five patients with emergency syncope admitted to our hospital from January 2019 to April 2021 were reviewed. The clinical data of all patients were retrospectively analyzed. The common causes were analyzed and summarized, and the strategies in clinical treatment were proposed. Results The main causes of syncope are neuroreflex syncope, follow by cardiac syncope, cerebral syncope, orthostatic hypotension syncope, hysterical syncope and unexplained syncope. They accounted for 35.3%, 30.6%, 15.3%, 12.9%, 3.5%, and 2.4%, respectively. Conclusion Emergency department physicians should evaluate emergency syncope patients in time, identify patients as soon as possible, confirm the etiological diagnosis, and give reasonable and effective symptomatic treatment and treatment measures in order to improve the prognosis and ensure the life safety and quality of patients.
An 8-lncRNA signature predicts the survival of triple-negative breast cancer patients without germline BRCA1/2 mutation
Authors: LIU Minling , DAI Wei , ZHU Mengyuan , LI Xueying , WEI Min , LI Lei , FANG Shuo
Published: January 2022

Purpose: TNBC with germline BRCA1/2 mutation (gBRCAm) have higher sensitivity to DNA damaging agents including platinum-based chemotherapy and PARP inhibitors. But the treatment of TNBC without gBRCAm remains challenging. This study aimed to develop a long non-coding RNA (lncRNA) signature of TNBC patients without gBRCAm to improve risk stratification and optimize individualized treatment. Methods: 98 TNBC patients without gBRCAm were acquired from The Cancer Genome Atlas database. The univariable Cox regression analysis and LASSO Cox regression model were applied to establish an lncRNA signature in the training cohort. Then Kaplan–Meier survival curve and time-dependent ROC curve were used to validate the prognostic ability of the signature. The qPCR assay was performed to confirm the expressions and clinicopathological correlations of two potential lncRNAs HAGLROS and TONSL-AS1 in 30 paired clinical triple-negative breast cancer samples without gBRCAm. Results: We developed an 8-lncRNA signature in the training cohort including HAGLROS, AL139002.1, AL391244.2, AP000696.1, AL391056.1, AL513304.1, TONSL-AS1 and AL031008.1. Patients with higher risk scores showed significantly worse overall survival compared to those with lower risk scores (P=0.00018 and P =0.0068 respectively). 30 paired specimens of TNBC without gBRCAm in our center showed that two potential lncRNAs HAGLROS and TONSL-AS1 were found frequently overexpressed, and significantly associated with tumor grade and invasion. Conclusion: We constructed a novel 8-lncRNA signature which significantly associated with the overall survival of TNBC patients without gBRCAm. Among those 8 lncRNAs, HAGLROS and TONSL-AS1 may be potential therapeutic targets which function needed further exploration.