bluuebunny/crossref_metadata_2025 huggingface dataset:
Adolescent girls trapped in early marriage social norm in rural Ethiopia: A vignette-based qualitative exploration
Authors: Tewahido Dagmawit , Worku Alemayehu , Tadesse Amare W. , Gulema Hanna , Berhane Yemane
Published: February 2022

Background

Early marriage is not uncommon in Ethiopia, particularly for adolescent girls in rural settings. Social norms are among the factors believed to perpetuate early marriage practices. This qualitative study explores social norms surrounding adolescent girls’ marriage practices in West Hararghe, Ethiopia.

Methods

This study used the qualitative inquiry method to explore social norms in rural Ethiopia. Focus group discussions were conducted with purposively sampled married and unmarried adolescent girls, adolescent boys, and parents. A total of 158 individuals participated in the study, comprising 95 adolescents and 63 parents. Data were collected using locally developed vignettes. A thematic framework analysis approach using the Social Norms Analysis Plot (SNAP) was employed to diagnose and understand social norms.

Results

Adolescent girls’ marriage was found to be mainly influenced by their peers who conform to prevailing social norms. Marrying one’s first suitor was considered an opportunity not to be missed and a symbol of good luck. Relatives, neighbors, and marriage brokers facilitate adolescent girls’ marriage in accordance with the local social norms. Girls usually accept the first marriage proposal regardless of their age, and they are highly expected to do so by their peers, parents, and influential others. Exceptions from the early marriage social norm include adolescent girls determined to continue their education and those having supportive teachers.

Conclusions

In this study context, social norms strongly encourage early marriage and are mainly perpetuated by peers of adolescent girls and influential adults. A strong determination to continue education on the part of girls, strong school performance, and supportive schoolteachers are important conditions for circumventing social norms on early marriage. As social norms evolve slowly, we recommend periodical assessment in order to develop locally appropriate interventions against early marriage.
Diagnostic and prognostic significance of cell death markers in patients with cirrhosis and acute decompensation
Authors: Stoffers Philipp , Guckenbiehl Sabrina , Welker Martin Walter , Zeuzem Stefan , Lange Christian Markus , Trebicka Jonel , Herrmann Eva , Welsch Christoph
Published: February 2022

Background

The transition from compensated to decompensated liver cirrhosis is a hallmark of disease progression, however, reliable predictors to assess the risk of decompensation in individual patients from routine diagnostics are lacking. Here, we characterize serum levels of cell death-associated markers and routine biochemistry from patients with chronic liver disease with and without decompensation.

Methods

A post-hoc analysis was based on prospectively collected clinical data from 160 patients with chronic liver disease, stably compensated or decompensated at baseline or during follow-up, over a median period of 721 days. Serum levels of damage-associated molecular patterns (DAMPs) and routine biochemistry are quantified at baseline (for all patients) and during follow-up (for patients with acute decompensation). The panel of DAMPs assessed in this study comprises high-mobility group-box protein 1 (HMGB1), cytochrome C (cyt C), soluble Fas-ligand (sFasL), interleukin 6 (IL-6), soluble cytokeratin-18 (CK18-M65) and its caspase‐cleaved fragment CK18-M30.

Results

In this cohort study, 80 patients (50%) were diagnosed with alcoholic liver cirrhosis, 60 patients (37.5%) with hepatitis C virus- and 20 patients (13.5%) with hepatitis B virus-related liver cirrhosis. At baseline, 17 patients (10.6%) showed decompensated liver disease and another 28 patients (17.5%) developed acute decompensation during follow-up (within 24 months). One hundred fifteen patients showed stable liver disease (71.9%). We found DAMPs significantly elevated in patients with decompensated liver disease versus compensated liver disease. Patients with acute decompensation during follow-up showed higher baseline levels of IL-6, sFasL, CK18-M65 and–M30 (P<0.01) compared to patients with stably compensated liver disease. In multivariate analyses, we found an independent association of baseline serum levels of sFasL (P = 0.02; OR = 2.67) and gamma-glutamyl transferase (GGT) (P<0.001; OR = 2.1) with acute decompensation. Accuracy of the marker combination for predicting acute decompensation was high (AUC = 0.79). Elevated aminotransferase levels did not correlate with decompensated liver disease and acute decompensation.

Conclusions

DAMPs are elevated in patients with decompensated liver disease and patients developing acute decompensation. The prognostic value of a marker combination with soluble Fas-ligand and GGT in patients with liver cirrhosis should be further evaluated.
Insights into POT1 structural dynamics revealed by cryo-EM
Authors: Smith Emmanuel W. , Lattmann Simon , Liu Zhehui Barry , Ahsan Bilal , Rhodes Daniela
Published: February 2022

Telomeres are protein-DNA complexes that protect the ends of linear eukaryotic chromosomes. Mammalian telomeric DNA consists of 5′-(TTAGGG)n-3′ double-stranded repeats, followed by up to several hundred bases of a 3′ single-stranded G-rich overhang. The G-rich overhang is bound by the shelterin component POT1 which interacts with TPP1, the component involved in telomerase recruitment. A previously published crystal structure of the POT1 N-terminal half bound to the high affinity telomeric ligand 5′-TTAGGGTTAG-3′ showed that the first six nucleotides, TTAGGG, are bound by the OB1 fold, while the adjacent OB2 binds the last four, TTAG. Here, we report two cryo-EM structures of full-length POT1 bound by the POT1-binding domain of TPP1. The structures differ in the relative orientation of the POT1 OB1 and OB2, suggesting that these two DNA-binding OB folds take up alternative conformations. Supporting DNA binding studies using telomeric ligands in which the OB1 and OB2 binding sites were spaced apart, show that POT1 binds with similar affinities to spaced or contiguous binding sites, suggesting plasticity in DNA binding and a role for the alternative conformations observed. A likely explanation is that the structural flexibility of POT1 enhances binding to the tandemly arranged telomeric repeats and hence increases telomere protection.
Actualización del tratamiento del cáncer de tiroides con radioyodo
Authors: Tamayo-Alonso Pilar , Martín-Gómez Esther , García-Talavera Paloma , Cañadas-Salazar José , Peñaherrera-Cepeda Carolina , Díaz-González Luis Gonzaga
Published: February 2022

El tratamiento del carcinoma diferenciado de tiroides (CDT) con radioyodo (RAI) se viene realizando durante más de 70 años. Sin embargo, no existe consenso en cuanto a indicaciones, dosis y otros aspectos relacionados con el cuidado de los pacientes. Es más, en los últimos años se ha cuestionado la necesidad de terapia adicional con RAI en los pacientes con carcinoma diferenciado de tiroides (CDT) tras la cirugía, como lo ha hecho la guía ATA 2015. Cuestionamiento que no ha sido suscrito por las sociedades Europea y Americana de Medicina Nuclear (EANM y SNMIM, respectivamente), lo que ha dado lugar a se produzcan encuentros (Encuentros de La Martinica) entre la EANM, la SNMIM y las Sociedades Americana (ATA) y Europea de Tiroides (ETA). Se han celebrado dos encuentros, en 2018 y 2019, en los que se establecieron unos principios (Principios de La Martinica). Estos principios y los resultados de las publicaciones más recientes, en cuanto a la potencialidad de la terapia con RAI en pacientes con CDT, van a ser objeto de desarrollo en este trabajo para llevar a cabo una actualización del tratamiento del CDT con RAI.
Patent Ductus Arteriosus Device Closure with Venous Only Access - A Retrospective Analysis
Authors: Deshabandu Vinayakumar , Kalathingathodika Sajeer , Shivakumar Suresh
Published: February 2022

BACKGROUND Patent ductus arteriosus (PDA) can be closed percutaneously by a device with and without arterial access. The conventional technique involves a femoral arterial as well as femoral venous access for closure. Here we discuss our institutional data in closing the PDA without arterial access. We wanted to study retrospectively the feasibility and outcome of PDA device closure in young children via femoral vein without femoral arterial access. METHODS From November 2011 to March 2018, 228 patients were evaluated clinically and echocardiographically for PDA device closure and 201(88 %) were found suitable. These 201 patients who underwent transcatheter PDA closure via femoral venous access were included in the study. Detailed 2D echocardiography and Doppler assessment were performed before the procedure. During transcatheter closure, fluoroscopic injections were done in two views by the catheter stationed at the PDA ampulla into the descending thoracic aorta. All PDAs were closed by Amplatzer duct occluder-I (ADO1 device). The detailed echocardiographic assessment was performed in each case before releasing the device from the delivery cable and at 5 minutes and 10-minute intervals thereafter till there was no significant flow across the duct. Echocardiography was performed immediately after the device deployment, at 12 hours and 24 hours. RESULTS Total 201 patients underwent PDA device closure via femoral venous access. The mean age was 1 year and 6 months (range 6 months to 47 years). The mean weight was 15 kg (range 5 to 66 kg). Females constituted 67.6 % (136 patients). 9 patients (4.4 %) had Down syndrome and 12 (5.9 %) had additional cardiac problems. In 108 patients, 6x8 size device was placed (53.7 %), in 44 patients, 4x6 size device (21.9 %), 30 patients with 8x10 size devices (14.9 %) and a few patients with other sizes. Two patients developed immediate complications which were addressed appropriately. CONCLUSIONS PDAs can be safely closed without arterial access. Operators’ skill and experience determine a successful outcome. Patient selection and detailed assessment of PDA before the procedure is of paramount importance. This transcatheter closure without arterial access makes the procedure simpler with low morbidity and complications. KEY WORDS Congenital Heart Disease, Patent Ductus Arteriosus, Device Closure, Amplatzer Duct Occluder
To Assess the Effectiveness of Nesting on Posture and Movements among Newborns in Selected Hospitals of Wardha District
Authors: Meshram Khushbu Manohar , Lokhande Shalini Hemraj , Sakharwade Prerna Tarachand
Published: February 2022

BACKGROUND Healthy posture can enhance sleep breathing and digestion, and protects internal organs from cramping. Strong posture may enhance quality of life. The fetus inutero has consistent, dynamic uterine boundaries that continually promote return to a flexed midline position following periods of activity. Conversely, infants in the neonatal intensive care unit are subjected to the effect of gravity and have a tendency to assume flattened postures especially when they are either preterm or sick. This places the infant at increased risk of developing a typical posture and movement patterns both in the short and long term. The study aims to determine the effectiveness of nesting on posture and movements among the new-borns in selected hospitals of Wardha. METHODS A quasi-experimental design was used to conduct this study. Purposive sampling technique was used for the new-borns in selected hospital of Wardha, among 60 new-borns (trial and control groups will include 30 new-borns each). A questionnaire was used to collect socio-demographic data of children and mothers, and a revised standardised checklist on the Infant Posture and Motor Appraisal scale was employed to compare the pose and movement of new-born babies. Following the pre-test, in the experimental population, care was provided to the new-born children, i.e., the baby may be placed in a prone position or on the side with flexed extremities by supplying a "nest" with a rolling blanket. The upper part of the child's body is slightly elevated, which represents a spot as it's "cradled in the arm." Intervening nesting was given in 2 periods for 3 days for 15 minutes. The post test was carried out on the 4th day of the modified observational checklist of the Infant Posture and Motor Assessment scale 'for the assessment of the posture and motor performance of new-born babies. RESULTS In control group 13.33 % of new-borns had poor level of nesting on posture and movements, 66.67 % had average, 13.33 % had good and 6.67 % of the new-borns had excellent level of nesting on posture and movements. Mean nesting on posture and movements score was 5.36 ± 2.02 and mean percentage score was 44.72 ± 16.87. And in experimental group 13.33 % of new-borns had poor level of nesting on posture and movements, 23.33 % had average, 6.67 % had good and 56.67 % of the new-borns had excellent level of nesting on posture and movements. Mean nesting on posture and movements score was 8.13 ± 4.02 and mean percentage score was 67.77 ± 33.52. CONCLUSIONS Nesting is an indicator of relaxation that simulates a sense of lack of room in utero and making the infant less jittery. Nesting encourages the transition of the sleep cycle from intermittent disrupted periods into deep relaxed nights and happier days, thereby saving energy (may be wasted in crying) and reducing weight loss. KEY WORDS Roosting or Birdhouse, Position, Neonates.
Narrativa de enfermería: visión y patrones de conocimiento en la experiencia de cuidado de una persona con colostomía. Reporte de caso
Authors: Arrieta-Romero María Angélica , García Ordóñez Karol Andrea , Perea Copete Neyfer , Díaz-Rivadeneira Jocelin , Borja-González Juana , De las Salas Roxana , Segura- Barrios Ilubith María
Published: February 2022

La narrativa de las situaciones de enfermería resalta las vivencias y significados de la persona objeto de cuidado con un proceso de enfermedad y da cuenta de la relación de cuidado enfermero-paciente como aspecto clave para la recuperación de la salud física, mental y espiritual, teniendo como base el proceso de atención de enfermería. Se presenta la situación de enfermería de una persona mayor de 74 años de edad, posquirúrgica de laparotomía exploratoria más resección de masa en colon sigmoide, que derivó en una colostomía. Se resaltan situaciones relacionadas con la ansiedad y preocupación de parte de una de sus hijas por el estado de salud de su madre. Con base en la narrativa se analizaron los patrones de conocimiento personal, empírico, ético y estético, la visión del mundo de enfermería integrativa-interactiva, así como la aplicación de la teoría de rango medio de las transiciones; los supuestos de las propiedades de la transición de Afaf Meleis.
Riesgos laborales de tipo psicosocial y desgaste psíquico en trabajadores de una administración pública mexicana
Authors: Hernández-Gracia Tirso Javier , Carrión-García María de los Ángeles
Published: February 2022

Objetivo: La finalidad del presente estudio es identificar la relación de los riesgos laborales de tipo psicosocial y el desgaste psíquico con respuestas de estrés en 985 trabajadores de una administración pública mexicana. Materiales y métodos: El diseño del estudio es no experimental, transversal y cuantitativo. Se aplicó la batería para el estudio de las condiciones de trabajo de carácter psicosocial CTCPSMAC, validada para población iberoamericana, con Alpha de Crombach 0.927 y población mexicana 0,931. Se realizó el análisis de datos a través del programa IBM SPSS Statistics 21, mediante un análisis bivariado y regresión logística binaria. Resultados: Características personales, relaciones interpersonales en el trabajo y carga y ritmo de trabajo, están asociados a respuestas cognitivo-emocional, conductual y fisiológica. Ambientes laborales y amortiguadores del riesgo psíquico, están asociados a las respuestas conductual y fisiológica. Concepción de las tareas del puesto de trabajo está asociada a las respuestas cognitivo-emocional y fisiológica. La exposición a una mala interrelación trabajo con problemas familiares o sociales, y características de la empresa está asociada a respuesta conductual. Conclusiones: La investigación mostró que en la organización pública objeto de estudio existe una relación significativa entre los factores de riesgo psicosocial del entorno laboral y las respuestas de estrés por parte de los trabajadores que integran la misma, poniendo en riesgo la salud de éstos, por lo que es importante considerar el cumplimiento de la Norma Oficial Mexicana NOM-035-STPS-2018, que recién entró en vigencia.
El uso de videojuegos seriosen ciencias para la salud
Authors: Ladino-Cañas Paola Karina , Caicedo-Eraso Julio César
Published: February 2022

Objetivos: Realizar una revisión del uso de Videojuegos Serios (VJS) aplicados en las diferentes áreas del proceso salud-enfermedad: Prevención primaria, prevención secundaria, prevención terciaria y enseñanza en Ciencias para la Salud (CPS); con el fin de concretar conceptos y hacer una difusión de la información. Materiales y métodos: Se realizó una búsqueda en PubMed, ScienceDirect, Cochrane Library, Bireme y Dialnet, mediante la estrategia: {[Serious game] AND [Health]}. Se complementó la información con una búsqueda adicional con la palabra [Serious game] y se incluyeron los artículos de interés para el estudio. Resultados: Los VJS se utilizan en múltiples campos; se encontraron 43 artículos relacionados con los VJS; 15 artículos en prevención primaria, 10 en prevención secundaria, 9 en prevención terciaria y 9 en enseñanza. Para el área de diagnóstico se encontró un artículo; siendo este campo el más limitado para la aplicación de los VJS. Conclusiones: Los VJS son videojuegos con objetivos diferentes al ocio siendo un campo innovador en áreas como CPS. Los VJS han tenido un impacto positivo, pueden ser aplicados en los diferentes niveles de prevención de la enfermedad y enseñanza de la salud; sin embargo aún falta el desarrollo principalmente en áreas como el diagnóstico. Se requiere estudios con poblaciones más numerosas y cambios estadísticamente significativos pero hasta el momento tienen un futuro prometedor.
Relationship between Hemineglect and Pain: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Authors: Morales-Osorio Marco  Antonio , Ordoñez-Mora Leidy  Tatiana , Guillén-Pájar Sherryl  Adriana , Cubillo-León Marco  Antonio , Mejía-Mejía Johana  Milena
Published: February 2022

Objective: To identify the relationship between hemineglect and pain. Methods: We conducted a systematic review with meta-analysis, examining the relations-hip between hemineglect and pain. The PRISMA criteria and the Covidence platform were used to select articles and extract data. Methodological quality was evaluated, a comparison was made using pain as an outcome measure, assessed with the visual analog scale (VA S).Results: Out of a total of 340 studies, 4 were selected, 2 of which made it possible to unify pain measured through VA S; the effects were summarized using standardized mean diffe-rences (SMD), yielding -0.65, with values of [-1.02, -0.29], with statistical significance.Conclusions: There is moderate evidence of the relationship between negligence and pain. Despite the fact that from the clinical care processes it is presented regularly, and even the little scientific information available, it was established that there are specific pathologies that carry negligence and pain.
Early urban occupation in the Tarim Basin: recent fieldwork results from the fortified site of Kuiyukexiehai'er (Koyuk Shahri)
Authors: Dang Zhihao , Li Chunchang , Zhang Xiangpeng , Xu Youcheng , Li Yue , Tian Duo , Zhang Chengrui
Published: February 2022

Archaeological fieldwork at the fortified site of Kuiyukexiehai'er (Koyuk Shahri) in the Xinjiang Uygur Autonomous Region of north-western China yields the earliest known evidence for urban occupation in the Tarim Basin, providing new insights into early urbanism and agro-pastoral subsistence practices in the region during the first millennium BC.
Gait Speed Reference Values for Adults Aged 90 and Older: The 90+ Study
Authors: Colcord Katherine A. , Kawas Claudia H. , Corrada María M.
Published: February 2022

Background and Purpose:

Slow gait speed has been associated with adverse outcomes in older adults, but little data exist for those 90 years and older, a group often referred to as the “oldest old.” We aimed to establish reference values for gait speed in men and women 90 years and older.

Methods:

The 90+ Study is a population-based longitudinal study of aging. Our analyses of gait speed included participants who were evaluated in person and were ambulatory. Gait speed was assessed using the 4-m walk test. We calculated means, standard deviations, and percentiles stratified by age, sex, and use of assistive device.

Results and Discussion:

The 797 participants had a mean age of 93.5 years. Of these, 73.9% were women, 39.5% had a college education, and 98.6% were White. The overall mean gait speed was 0.58 m/s (women = 0.55 m/s, men = 0.65 m/s). In participants who did not use an assistive device, the overall mean gait speed was 0.66 m/s (women = 0.63 m/s, men = 0.71 m/s). In those who used a device, the overall mean gait speed was 0.38 m/s (women = 0.37 m/s, men = 0.43 m/s). Gait speed decreased with increasing age. Men had consistently higher average gait speeds compared with women across age categories. Men and women who used assistive devices had lower average gait speeds across age categories compared with men and women who ambulated with no device. Average gait speeds in our oldest-old cohort were slower than those of older adults younger than 90 years in previous studies.

Conclusions:

This study is the first to establish gait speed reference values specific to adults 90 years and older. Age-appropriate reference values are crucial to the accurate interpretation of clinical measures for patients in their 90s and above.
WNT16 from decidual stromal cells regulates HTR8/SVneo trophoblastic cell function via AKT/beta-catenin pathway
Authors: Li Xinyi , Shi Jiaxin , Zhao Weijie , Huang Xixi , Cui Liyuan , Liu Lu , Jin Xueling , Li Djin , Zhang Xuan , Du Meirong
Published: February 2022

Decidual stromal cells (DSCs) modulate the function of trophoblasts through various factors. Wnt signaling pathway is active at the maternal–fetal interface. Here, we isolated endometrial stromal cells (ESCs) from women of reproductive ages and DSCs from normal pregnancy during the first trimester (6–10 weeks). Real-time quantitative PCR and western blotting were used to screen out the most variable WNT ligands between ESCs and DSCs, which turned out to be WNT16. Both culture mediums from DSCs and recombinant protein of human WNT16 enhanced the survival and invasion of HTR8/SVneo trophoblastic cells. Furthermore, the regulation of DSCs on trophoblast was partly blockaded after we knocked down WNT16 in DSCs. Treating HTR8/SVneo trophoblastic cells with small molecular inhibitors and small interfering RNA (siRNA), we found that the activity of AKT/beta-catenin (CTNNB1) correlated with the effect of WNT16. The crosstalk of WNT16/AKT/beta-catenin between DSCs and trophoblasts was determined to be downregulated in unexplained recurrent spontaneous abortion. This study suggests that WNT16 from DSCs promotes HTR8/SVneo trophoblastic cells invasion and survival via AKT/beta-catenin pathway at the maternal–fetal interface in human early pregnancy. The disturbance of this crosstalk between DSCs and trophoblasts might cause pregnancy failure.
Postrzeganie dysmorfofobii przez pacjentów leczonych w gabinetach chirurgii plastycznej i medycyny estetycznej – badanie kwestionariuszowe
Authors: Walczyńska Anita , Jaworski Aleksander P. , Drozdowski Piotr , Drozdowska Aneta
Published: February 2022

Dysmorfofobia (ang. body dysmorhic disorder – BDD) to problem coraz częściej spotykany w gabinetach chirurgii plastycznej i medycyny estetycznej. Zaburzenie polega na drastycznym, nieadekwatnym braku zadowolenia z własnego ciała i zwracaniu uwagi na jego niedoskonałości. Szacuje się, że 1 na 50 osób w populacji światowej przejawia objawy BDD. Wielu pacjentów miewa myśli samobójcze, a część z nich wieńczy je próbą samobójczą. Skala problemu dowodzi konieczności zwiększenia świadomości o chorobie zarówno wśród lekarzy, jak i pacjentów. Cel pracy Celem niniejszego badania było sprawdzenie stanu wiedzy i opinii pacjentów gabinetów chirurgii plastycznej i medycyny estetycznej na temat BDD. Materiał i metody Za narzędzie badawcze posłużył autorski kwestionariusz składający się z 25 pytań zamkniętych, w tym 5 wielokrotnego wyboru. W badaniu wzięło udział 55 kobiet i 47 mężczyzn. Pytania dotyczyły wiedzy pacjentów na temat BDD: objawów BDD, problemów diagnostycznych związanych z BDD, zachowania osób chorych na BDD, epidemiologii BDD, wielospecjalistycznej opieki nad pacjentami z BDD, ze szczególnym uwzględnieniem roli specjalisty chirurgii plastycznej, implikacji prawnych, a także opinii pacjentów na temat zaangażowania chirurgów plastycznych w proces diagnostyczny BDD. Wyniki Pomimo że większość badanych uważa BDD za zaburzenie, które nie stanowi trudności diagnostycznej, według części respondentów specjaliści chirurgii plastycznej i medycyny estetycznej w zbyt małym stopniu angażują się w walkę z chorobą. Wnioski Należy przywiązywać większą wagę do działań edukacyjnych oraz zachować zwiększoną czujność, konsultując pacjentów z grupy ryzyka, szczególnie biorąc pod uwagę tendencję wzrostową do poddawania się przez osoby chore na BBD operacjom plastycznym i zabiegom medycyny estetycznej.
STUDI KELAYAKAN LOKASI BARANG MUATAN KAPAL TENGGELAM (BMKT) SEBAGAI WISATA SELAM DI KABUPATEN KARAWANG JAWA BARAT
Authors: Kelana Perdana Putra , Oktavian Sandra Moerti , Fadillah Muhammad Fiqi , Arkham Muhammad Nur
Published: February 2022

Benda Muatan Kapal Tenggelam (BMKT) dapat dimanfaatkan sebagai wisata selam. Kabupaten Karawang memiliki 3 lokasi BMKT yang akan dimanfaatkan untuk wisata selam. Studi ini dilakukan pada bulan Oktober 2019 dengan mengamati 4 stasiun pengambilan data yaitu Karang Kapalan, Karang Sendulang dan Karang Tamiyang serta Pulau Gede. Metode yang digunakan dalam studi ini adalah metode survey. Adapun parameter yang diamati adalah jarak lokasi dari pantai, kondisi BMKT, dan kecerahan perairan serta kecepatan arus. Pengolahan data dilakukan untuk menghitung nilai Indeks Kelayakan Wisata (IKW) guna mengetahui kategori kelayakan wisata. Berdasarkan hasil studi, BMKT yang berupa fragmen keramik dalam kondisi tidak utuh dan keceraha perairan yang rendah menjadi penyebab nilai IKW rendah.  Nilai IKW ke-4 stasiun berada pada kisaran 39-41% dan termasuk kedalam kategori sesuai bersyarat.
PENGOLAHAN DIMSUM CUMI (Loligo sp.) DENGAN PENGGUNAAN KONSENTRASI KECAP ASIN YANG BERBEDA
Authors: Basri Basri , Harahap Kurnia Sada , Yelofeva Andiki
Published: February 2022

Cumi-cumi adalah produk kelautan yang banyak tersedia di perairan Indonesia. Beberapa cumi diproses. Cumi-cumi adalah jenis chepaloda yang dikenal di dunia perdagangan selain sotong dan gurita. Proses pembuatan dimsum dilakukan dengan melalui beberapa tahapan, mulai dari tahap penyiasan, pencucian, penggilingan, pencampuran rempah-rempah, menekan, mengukus, dan akhirnya tahap pengemasan dan pelabelan. terlalu mencurigakan, tekstur elastis dan rasa yang tidak hambar atau asin. Formulasi terbaik dari 3 perawatan dalam membuat dim sum adalah perawatan kedua, dengan kode sampel K.2, yaitu penambahan kecap 6% dan 12%, hal ini dibuktikan dengan uji hedonik oleh 30 panelis yang lebih memilih rasa, warna, rasa dan tekstur produk Dimsum perawatan ke-2 menggunakan modal Rp. 98.000 dalam 500 g dapat menghasilkan 18 cangkir dengan jumlah Dim Sum 126. Laba yang diperoleh sebesar Rp 28.000, analisis R/C 3,85.
ANALISA PEMBAGIAN BEBAN PADA INSTALASI LISTRIK TIGA PHASA KAPAL PENANGKAP IKAN STUDI KASUS PADA KM. SUMBER REZEKI
Authors: Demeianto Bobby , Arkan Muhammad At , Priharanto Yuniar Endri , Siahaan Juniawan Preston
Published: February 2022

Energi listrik saat ini telah menjelma menjadi kebutuhan pokok bagi para penggunanya. Dalam suatu kapal penangkap ikan, energi listrik selain dibutuhkan dalam kegiatan navigasi juga dibutuhkan sebagai alat bantu dalam proses penangkapan ikan dimana dalam proses  penangkapan ikan tersebut menggunakan lampu sorot atau flood light untuk memancing kehadiran ikan tangkapan mendekati kapal. Pada umumnya system instalasi listrik tiga phasa dapat dikatakan baik bila system pembagian beban pada system tersebut seimbang. Penelitian ini memiliki tujuan untuk mencari nilai presentase ketidakseimbangan arus listrik pada instalasi listrik tiga phasa pada kapal penangkap ikan KM. Sumber Rezeki. Selain itu penelitian ini juga memiliki tujuan untuk mencari nilai rata-rata presentase pembebanan arus listrik pada setiap phasa pada generator tersebut dan juga mencari nilai efisiensi generator pada KM. Sumber Rezeki. Dari hasil perhitungan didapatkan bahwa presentase ketidakseimbangan instalasi listrik tiga phasa KM. Sumber Rezeki pada saat generator beroperasi maksimal berada pada angka 6,5%. Dari hasil perhitungan juga didapatkan bahwa rata-rata presentase pembebanan pada generator listrik KM. Maradona adalah senilai 68,6% dengan nilai arus rata-rata sebesar 68 Ampere. Berbanding lurus dengan nilai arus rata-rata, nilai daya semu rata-rata KM. Sumber Rezeki berada pada angka 45,5 kVA dengan rata-rata nilai efisiensi generator sebesar 70,06%.
MASCULINIDADES E PSICODRAMA: CONTRIBUIÇÕES DA TÉCNICA DO DESDOBRAMENTO DO EU
Authors: Schweitzer Lucas , Kersbaumer Luciana Moskorz
Published: February 2022

RESUMO Este artigo tem como objetivo compreender os benefícios da utilização da técnica do desdobramento do eu em demandas psicológicas relacionadas às masculinidades em um processo de psicodrama bipessoal. Por meio de uma pesquisa-ação com um homem adulto, foi possível identificar conservas culturais vinculadas ao papel de gênero. Observou-se uma suposta obrigatoriedade de vigor físico e psicológico, de não demonstração de sentimentos, vulnerabilidades e sensibilidade, bem como uma exigência constantede trabalho e produtividade. Ao se fazer os eus internos do protagonista contracenarem por meio da técnica do desdobramento do eu, possibilitou-se o encontro com caminhos efetivos de busca da saúde biopsicossocial, por vezes integrando e/ou acionando outros eus para atuarem diante dos desafios cotidianos.
Maßnahmen zur Krankheitsprävention bei Schülerinnen und Schülern der Gesundheits- und Krankenpflege: eine kontrollierte sechswöchige Pilotstudie
Authors:   HSD Hochschule Döpfer, University of Applied Sciences, Köln, Funke Simone , Möckel Luis ,   HSD Hochschule Döpfer, University of Applied Sciences, Köln
Published: February 2022

Interventions for disease prevention among nursing students: A controlled six-week pilot study Objectives: This study was designed to evaluate whether training on disease prevention results in measurable behavioural change among nursing students in terms of number of steps, sport units and portions of fruit/vegetables. Methods: Two classes of nursing students were allocated into an interventional and a control group. Only the interventional group received training on health promotion and disease prevention, but both groups were monitored for 42 days. The main end points were number of steps per day, number of sport units per week and portions of fruit/vegetables per day. Mean values and standard deviations (SD) were calculated and statistically compared between both groups. Results: A total of 46 students were included in the study. The mean age of the participants was 21.3 (SD 5.2) years in the interventional group (n=22) and 19.0 (SD 1.4) years in the control group (n=24). Participants in the interventional group walked more steps per day and completed more sport units per week over the whole study period, with significant differences compared to the control group only during the period from day 29 to day 42 (Steps: 6258 vs. 3654; Δ: 2604.4 [95% CI: 556.8; 4652.1]; p=0.015/Sport units: 3.1 [SD 2.1] vs. 1.6 [SD 1.4]; Δ1.5 [95% CI: 0.2; 2.3]; p=0.03) respectively. There was no significant difference between both groups for portions of fruit/vegetables per day. Conclusion: This pilot study indicates that the cost-effective training of nursing students could result in a change in exercise behaviour. Nevertheless, these are only initial findings and further long-term studies are needed before definitive conclusions can be drawn. Keywords: disease prevention – nursing students – nursing
Yönlü aşırı akım röleleri koordinasyon problemi için arıza akımı sınırlama mekanizmalı adaptif koruma yöntemi
Authors: YEROĞLU Celaleddin , AKDAĞ Ozan
Published: February 2022

Güç sistemlerinin korunmasında Yönlü Aşırı Akım Röleleri (YAAR) koordinasyonu önemli bir konudur. Bu makalede doğrusal olmayan ve yüksek kısıtlara sahip YAAR koordinasyonu problemi ele alınmıştır. YAAR'nin optimum koordinasyonunu sağlamak için literatürde verilen amaç fonksiyonuna röle ayar kısıtları bir ağırlık faktörü ile eklenerek, modifiye edilmiştir. Önce YAAR probleminin optimum koordinasyonunun hesaplanmasında Buharlaşma Hızı Kontrollü Su Çevrim Algoritması (BH-SÇA) ve Harris Şahin Optimizasyon (HŞO) algoritmaları kullanılmıştır. Bu algoritmalar 9-bara test sistemine uygulanmıştır. Ayrıca BH-SÇA ve HŞO kullanılarak elde edilen sonuçlar, literatürdeki diğer algoritmalar kullanılarak elde edilen sonuçlarla karşılaştırılmıştır. Daha sonra Dağıtık Üretim (DÜ) sistemi barındıran güç şebekelerinde değişen güç sistemi koşullarına uyum sağlayan yeni adaptif bir koruma yöntemi önerilmiştir. Bu yöntemde YAAR'nin optimum koordinasyonunun sağlanmasında HŞO algoritması kullanılmıştır. Ayrıca, bu yeni adaptif koruma yönteminde, güç sistemlerinde kritik arıza noktasını aynı anda akım ve gerilim indeksini temel alarak belirleyen Arıza Akım Sınırlama (AAS) mekanizmalı bir yapı önerilmiştir. Sonrasında bu yeni adaptif koruma yöntemi 10 bara Türkiye dağıtım sistemine uygulanarak, çalışmanın etkinliği tartışılmıştır.
Tepe akım modu kontrollü izolesiz zeta dönüştürücünün küçük işaret analizi, benzetimi ve deneysel olarak gerçeklemesi
Authors: YILMAZ Abdurrahman , GARİP Muhammed
Published: February 2022

Bu çalışmada, matematiksel analizi gerçekleyen deneysel düzenekle birlikte bir izolesiz Zeta dönüştürücü sunulmaktadır. İlk olarak, tepe akım-mod kontrollü dönüştürücünün küçük işaret analizi gerçekleştirildi. Bunun için sürekli akım modunda PWM-anahtar modeli kullanıldı ve çıkış kondansatörünün eşdeğer seri direncini içeren çıkış gerilimi transfer fonksiyonu elde edildi. Kutuplar ve sıfırlar sembolik formda verildi ve sayısal bir örnek ile doğruluğu ispatlandı. Tepe akım-mod PWM-anahtar modelinin kullanılmasıyla elde edilen transfer fonksiyonunun paydası 5. mertebeden bir polinom olduğu için, kutuplar ve kalite faktörlerine ait çözümlerin takriben bulunması için yaklaşık kök analiz metodu kullanıldı. Önerilen Zeta dönüştürücünün Bode diyagramları için PSIM ortamında benzetim gerçekleştirildi ve benzetim sonuçları sembolik olarak elde edilen transfer fonksiyonun Bode diyagramları ile karşılaştırıldı. Daha sonra deneysel prototip oluşturuldu ve deney düzeneği hazırlandı. Gerçekleştirilen deneysel çalışmalar neticesinde sonuçların, anahtarlama frekansının yarı seviyesine kadar matematiksel sonuçlar ile uyum içerisinde oldukları gösterildi.
Sustainable Low-Carbon Development of Urban Public Transport: International and Russia’s Experience
Authors:   Lomonosov Moscow State University, Kudryavtseva Olga V.
Published: February 2022

The rapid growth of cities all over the world has inevitably led to the aggravation of economic, social and environmental problems. In this regard, developing «green», low-carbon, circular and other new economic models is necessary. Transport sector is an important source of greenhouse gas emissions and air pollutants. The purpose of this work is to assess the impact of urban public transport, especially electric buses, on the air quality. The authors have analyzed international and Russia’s experience of the low-carbon development of urban public transport and evaluated the environmental effects of transitioning to electric buses in Moscow using a regression model and data visualization tools. The results have shown that integrating electric buses into an urban transport system can be considered as a step towards the low-carbon development of the transport sector. The authors have identified a decrease in carbon monoxide (CO) pollution in the districts of Moscow where there are electric bus routes. Although the authors managed to demonstrate positive aspects of using e-buses instead of traditional ones, the proposed hypotheses were not fully confirmed due to limited data and a small number of electric bus routes at an early stage of the project. The results of the work can be used both in theoretical studies of sustainable development and practical implementation of programs for the low-carbon development of an urban transport network
A Comparative Analysis of Socio-economic Development of Cities with a Population Over a Million People
Authors:   Institute of Economics and Industrial Engineering SB RAS, Novoselov Alexander S.
Published: February 2022

The article provides a comparative analysis of the socio-economic development of cities with a population of 1 million to 2 million people. The basic methods of research and assessment of socio-economic development of cities and regions are identified and analyzed. The authors propose the method for cluster analysis of key factors of the development of cities with more than a million inhabitants. Based on the results of the study, the authors have outlined the factors with the greatest influence on the development of cities with population over a million people, the dependence of the GRP per capita as the indicator of the level of socio-economic development on such factors as availability of access to the sea, developed transport infrastructure, favorable climatic conditions
Empirical Assessment of the Efficiency of Sustainable Innovative Development of the Resource-based Regions
Authors:   Siberian Federal University, Ruiga Irina R.
Published: February 2022

The article is devoted to the formation of assessment tools for monitoring threats to the innovative development of the constituent entities of the Russian Federation from the perspective of criteria for efficiency and sustainability of performance. Taking into consideration investigated approaches and advantages and disadvantages identified in the course of the research, the author developed an assessment approach of the efficiency of the regional sustainable innovative development from the perspective of sustainability. The assessment mechanism is based on the calculation of the integral index for two projections (innovative potential and innovative development efficiency). Testing of the current approach is implemented on the example of the resource-type regions of the Russian Federation. The research results can be used by regional government to monitor risks and threats in the innovation sector, as well as to adjust existing regulatory and strategic documents and improve mechanisms to ensure sustainable regional innovative development
Transition to the Concept of «Smart City» in the Regions of the Southern Federal District: a Correlation Matrix of Indicators of a Smart and Sustainable City
Authors:   Volgograd State Technical University, Akimova Olga E.
Published: February 2022

A «smart city» is based on the indicators of a traditional «sustainable city», however, due to innovative development, it expands the elementary composition and complexity of system connections in a «sustainable city», updating, improving and gradually replacing it. In this regard, within the framework of this study, an attempt was made to identify indicators that can describe a «smart city», to determine the relationship of these indicators with each other, as well as to build a correlation matrix of links between indicators of a smart and sustainable city. The study was carried out using correlation-regression analysis using a linear correlation coefficient. The simulation results are presented for the regions of the Southern Federal District of the Russian Federation and allow us to draw conclusions about the use of the identified relationships in the management of the development of these regions. To determine the level of entry of a particular region into the digital space, indicators were identified that act as control nodes that allow you to manage the process of transition to the «smart» category and regulate the pace of the transition process itself. A comparative analysis of correlation matrices revealed a tendency towards a weakening of the dependence of the indicators of a «smart city» on indicators of a «sustainable city», which indicates a gradual transition of a territorial entity to the concept of a «smart city» and a gradual penetration of the results of scientific and technological progress and high technologies into various spheres of human life
Agent-Based Modeling of Spatial Economic Systems: а Review
Authors:   Novosibirsk State University, Tsyplakov Alexander A.
Published: February 2022

The paper describes the current state of agent-based modeling of geographical space and spatial economic systems. We explore reasons why this approach to modeling spatial phenomena is of particular interest. Agent-based models (ABMs) allow accounting for agents’ spatial heterogeneity, the existing structure of the space, locality of interactions between agents. A survey of approaches to introducing space into the models and examples of the existing spatial models is presented. There is a great variety of spatial ABMs, but they relate predominantly to the local and city level, rather than to the economy as a whole. Spatial ABMs at the level of large regions and countries are not yet sufficiently developed, but have good prospects in the future. With increasing availability of geodata and technological development in general the number of applications and coverage of spatial ABM will grow
The BRICS Stocks Index as an Aggregate Indicator of Regional Economic Development
Authors:   Financial University under the Government of the Russian Federation, Zharikov Mikhail V.
Published: February 2022

The topic is time-relevant, since today there is a strong need to find indicators showing a development path for countries after the pandemics of 2020 in specific regions of the world. This paper makes an attempt to create an indicator that is different and more representative of the BRICS than the indexes already in existence. The BRICS index offered here is a capitalisation-weighted average of daily quotations for the listed stocks which dynamics highly correlate with each other. The purpose of developing such an index is to monitor a general growth pattern of the BRICS’ economies and their corporations on the financial markets, both domestically and regionally, since they are at the core of the regions, they are in. The introduction of the BRICS index to the financial market can help increase investors’ appetite for the assets. It will make it easier to analyze the stock markets of the BRICS as well. The significance of such a rating is that it may lay the foundation for working out a trading strategy to deal in the stocks of the BRICS companies to get optimal returns. The BRICS stocks index can also be an indicator of regional development for countries dependent on the BRICS, as well as the product of financial engineering which may help attract investors and other professionals working on the financial market to accumulate growth and recovery funds for the trouble countries of the region
Elements of Programme Music in the Instrumental Works of the Late Period by Oleg Meremkulov (the Case of the Symphony Concerto for Cello, Piano and Orchestra)
Authors:   Dmitry Hvorostovsky Siberian State Academy of Arts, Naiko Natalia M.
Published: February 2022

This article reveals some aspects of the creative identity and later works of the greatest Krasnoyarsk composer O. Meremkulov. To understand the artistic aspirations and originality of O. Meremkulov’s works, his Symphony Concerto for Cello, Piano, String Orchestra, Percussion and Wind Ensemble (2015) is an illustrative piece of art. The concerto genre was conceived by the composer as a composition showing the essential problems of human existence, preserving the modus of a personal statement «in the first person». This has led to the introduction of epigraphs and programme titles of parts that not only tune the listener in a certain way, but are elements of concept and means of realising the author’s intentions. The musical analysis regarding the main intonational characteristics of all parts of the concerto, their relations, aspects and orientation of the development of musical thematism are correlated with possible interpretations of titles and epigraphs. This made it possible to come to the conclusion about the original programme music of the concerto. It is revealed by a combination of means functioning at various levels, addressing the sensations of different modalities, individual experience, cultural memory, as well as activating associative thinking and figurative representations. Not only part titles and epigraphs work in this respect, but also the author’s remarks introduced into the musical score and audio records with natural sounds during the performance. Programme music is also recognised in the process of thematic transformations that reflect the orientation of the Hero’s emotional experiences clarifying the essence of a certain image or reproducing a chain of events related to a certain plot. It has been suggested that this plot bizarrely refracts in the composer’s mind the real events experienced by him during different periods of life, sprouted into the subjective perception and understanding of artistic images of world culture. In his dialogue with the authors of past centuries, the composer reached a new level of generalisation, thereby capturing his ideas and feelings in an intonational form. This has led to the originality and unique harmony of the Symphony Concerto
Reflection of the Spiritual World of Nikita Grigorievich Stroganov in Church Art
Authors:   South Ural State University, Voroshin Semyon D.
Published: February 2022

In this article the author examines the peculiarities of the personalities of the Stroganovs, entrepreneurs and patrons of the arts at the example of the Nikita Grigorevich. The main pivotal concepts that existed in the culture of the Late Middle Ages are determined, the channels of their transmission in society are indicated. To understand the factors that influenced his worldview and were reflected in the art of the Late Middle Ages, the theory of identity was chosen, which determines the involvement of a person in certain areas of culture at universal, national and regional level. This phenomenon is realized through the adoption of fundamental values characteristic of society. The translators of these values and cultural codes in Russia during the late Middle Ages were the church, chronicles and books, public and family institutions and art. The latter is able to convey semantic concepts through a system of images and symbols filled with emotions and forming a person’s involvement with the themes and ideas of the works. The author describes the influence of the fundamental ideas of that time on the formation N. G. Stroganov’s spiritual world. It’s identified cultural codes that shape the personality of entrepreneur and found their manifestation in the art he revered