bluuebunny/crossref_metadata_2025 huggingface dataset:
Analyzing Questions About Alcohol in Pregnancy Using Web-Based Forum Topics: Qualitative Content Analysis (Preprint)
Authors: Frennesson Nessie Felicia , Barnett Julie , Merouani Youssouf , Attwood Angela , Zuccolo Luisa , McQuire Cheryl
Published: June 2024

BACKGROUND

Prenatal alcohol exposure represents a substantial public health concern as it may lead to detrimental outcomes, including pregnancy complications and fetal alcohol spectrum disorder. Although UK national guidance recommends abstaining from alcohol if pregnant or planning a pregnancy, evidence suggests that confusion remains on this topic among members of the public, and little is known about what questions people have about consumption of alcohol in pregnancy outside of health care settings.

OBJECTIVE

This study aims to assess what questions and topics are raised on alcohol in pregnancy on a web-based UK-based parenting forum and how these correspond to official public health guidelines with respect to 2 critical events: the implementation of the revised UK Chief Medical Officers’ (CMO) low-risk drinking guidelines (2016) and the first COVID-19 pandemic lockdown (2020).

METHODS

All thread starts mentioning alcohol in the “Pregnancy” forum were collected from Mumsnet for the period 2002 to 2022 and analyzed using qualitative content analysis. Descriptive statistics were used to characterize the number and proportion of thread starts for each topic over the whole study period and for the periods corresponding to the change in CMO guidance and the COVID-19 pandemic.

RESULTS

A total of 395 thread starts were analyzed, and key topics included “Asking for advice on whether it is safe to consume alcohol” or on “safe limits” and concerns about having consumed alcohol before being aware of a pregnancy. In addition, the Mumsnet thread starts included discussions and information seeking on “Research, guidelines, and official information about alcohol in pregnancy.” Topics discussed on Mumsnet regarding alcohol in pregnancy remained broadly similar between 2002 and 2022, although thread starts disclosing prenatal alcohol use were more common before the introduction of the revised CMO guidance than in later periods.

CONCLUSIONS

Web-based discussions within a UK parenting forum indicated that users were often unclear on guidance and risks associated with prenatal alcohol use and that they used this platform to seek information and reassurance from peers.
The Protective Effect of Artocarpus altilis Leaf Extract on Rat Models of Diethylene Glycol-Induced Hepatotoxicity
Authors: Susilo Jatmiko , Purwanto Bambang , Doewes Muchsin , Indarto Dono
Published: June 2024

Diethylene glycol (DEG) is an alcohol derivative, which is metabolized into toxic products and is one of the main causes of liver disease. This paper aims to determine the hepatoprotective effect of AA by analyzing the levels of MDA, AST, ALT, and liver hypertrophy in the DEG-induced rat model. Twenty-five male rats were divided into 5 groups: normal, DEG (0.75% v/v), AA1 (DEG + AA 100 mg/kg BW), AA2 (DEG + AA 200 mg/kg BW), and AA3 (DEG + AA 400 mg/kg BW). Rats were given DEG for 28 days ad libitum, and AA was administered from days 14 to 28 orally. Twenty-eight days later, serum levels of MDA, ALT, AST, and liver hypertrophy were determined. DEG induction increased body weight and liver hypertrophy, levels of MDA, ALT, and AST, and decreased the AST/ALT ratio, whereas treatment with AA was shown to reverse to normal conditions which were observed for 28 days depending on the dose of AA (p < 0.05). We conclude that treatment with AA is an effective therapeutic option as a hepatoprotector in a rat model induced by DEG in a dose-dependent manner. Future challenges need to be developed as prospective complementary drugs or phytopharmaceuticals.
Potential Role of Centella asiatica and Sauropus androgynus in High-Fat and High-Fructose Diet-Induced-Obesity Animal Model
Authors: Hasimun Patonah , Damayanti Erinna Putri , Sulaeman Agus
Published: June 2024

Obesity is a condition characterized by excessive fat accumulation, which leads to metabolic syndrome diseases such as hyperglycemia, hyperlipidemia, hyperuricemia, and hypertension. Efforts to reduce obesity can minimize the risk of the disease. This study aims to determine the antiobesity activity of a combination of Sauropus androgynus L. Merr (SA) and Centella asiatica L.Urban (CA) in a Swiss Webster obese mouse model. A total of 36 mice were randomly grouped into six groups, including the control group (receiving drug carriers), positive (receiving drug carriers), and standard (receiving orlistat 15.6 mg/kg BW). Three groups receiving a combination of SA & CA with a dosage ratio SA: CA includes 25:25 mg/kg BW, 25:50 mg/kg BW, 50:25 mg/kg. All groups (except the normal group) induced obesity with a high-fat and high-fructose (HFHF) diet for 28 days. The drug is given orally for 28 days. Body weight, feed index, feces index, organ index, fat index, serum triglyceride levels (TG), and percent inhibition of lipid peroxidation using malondialdehyde (MDA) absorbance were all measured. The results showed that there were significant differences in parameters of body weight, feed index, feces index, organ index, fat index, serum triglyceride (TG) level, lipid-peroxidation inhibition, and histology of adipocytes between groups of animals receiving a combination extracts compared to the positive control group (p<0.05). The study results concluded that the combination of SA and CA had antiobesity activity.
Antidiabetic Activity of Averrhoa bilimbi L. Fruit Extracts and the Identification of Active Compounds Using LC-MS and In silico Methods
Authors: Widiastuti Diana , Sinaga Siska Elisahbet , Warnasih Siti , Syahputri Yulian , Saputri Nurjanah Bella , Sustiprijatno  , Putra Wira Eka
Published: June 2024

Patients with diabetes mellitus require drugs that do not cause side effects in long-term use. In this era, many people use herbal medicine to treat diabetes mellitus. One species we can use as herbal medicine is Averrhoa bilimbi L., a plant whose fruit is known as belimbing wuluh and is used because it has value as an alternative medicine. This study aims to determine the antidiabetic activity of the active fraction of Averrhoa bilimbi L. fruit in vitro and in silico and to obtain the active compounds contained in the fruit fraction of starfruit (A. bilimbi L.) using Liquid Chromatography Mass Spectrometer (LC-MS). Sixteen organic compounds were identified using LC-MS analysis of the n-hexane fraction, which had the highest IC50 (7.03 μg/mL) antidiabetic activity compared to ethyl acetate (102.77 μg/mL) and n-butanol (181.65 μg/mL). In silico molecular docking, analysis was performed for all identified compounds to support the antidiabetic characteristics further. Computational predictions in this investigation revealed that two A. bilimbi fruit compounds with the greatest RT value, namely 2,3,4,5,6-pentaphenylbenzazocine (-16.0 kcal/mol) and Thraustochytroside A (-6.2 kcal/mol), exhibited higher binding affinity values than miglitol (-5.4 kcal /mol). This indicates that both compounds have promising futures as α-glucosidase inhibitor alternatives for treating diabetic disorders.
Optimization of Spray Drying Process of Mangiferin Extract from Mango Leaf (Mangifera indica L.) and Encapsulation for Diabetes Treatment
Authors: Nguyen Ngoc Nha Thao , Vo Duc Linh , Le Thi Thanh Yen , Nguyen Thi Trang Dai
Published: June 2024

Mangiferin is known as a major compound in mango leaves with various pharmacological effects such as antioxidant, antiviral, cancer, diabetes,... However, the poor solubility of mangiferin limits its pharmaceutical applications. Thus, this work’s major goal was to optimize the parameters of the spray-drying process in order to improve the dissolution of mangiferin in Mangiferin indica L. leaf extract and capsule formulation for diabetes treatment. Fourteen experiments were designed with Design Expert software and optimized process formulas with BC Pharsoft OPT software. Three independent variables were selected for surveying namely the ratio of mangiferin to excipients (X1), the ratio of maltodextrin in spray fluid composition (X2), and inlet air temperature (X3). The dissolution of mangiferin was shown as the percentage of this compound released within 5 minutes (Y1), 15 minutes (Y2), 30 minutes (Y3), and the percentage of hygroscopicity at 25oC (Y4). The results showed that the optimized spray drying process and formula which included the ratio of mangiferin and maltodextrin in the spray drying solution being 8.30% and 9.63%, respectively, the inlet air temperature of 156.26oC, blowing speed of 50 m3/s, pump flow of 3 mL/min possessed the dissolution of mangiferin in spray drying powder of 91.89 ± 2.43% at 30 minutes, the percentage hygroscopicity of 0.13 ± 0.13% at 25oC. The cause-effect relations and optimization of Mangiferin indica L leaf extract powder formulation were investigated and reported for the first time. The spray-dried powder capsule released more than 90% active ingredients in 30 minutes and showed significant hypoglycemic effects in inhibiting the α-glucosidase enzyme (IC 50 of 36.94 µg/mL equivalent to mangiferin in comparison with the commercial drug Glucobay (acarbose 176.09 µg/mL). In summary, the capsules containing the optimized formula of mangiferin spray-dried powder from Mangifera indica L. leaf extract have been successfully prepared and had potential antidiabetic effects in in-vitro settings.
Cognitive Strategies for the Management of Culture-Specific Items in English-Chinese Simultaneous Interpreting
Authors: Tao Chenping
Published: June 2024

Simultaneous interpreting presents significant cognitive challenges, particularly when interpreters encounter Culture-Specific Items (CSIs). This study explores the cognitive processes involved in interpreting CSIs between English and Chinese, focusing on the difficulties posed by the lack of extra-linguistic knowledge, comprehension ambiguity, and the absence of equivalents in the target language. Through comprehensive analysis and professional interviews, the research identifies and discusses effective coping strategies employed by interpreters to mitigate cognitive load. These strategies include paraphrasing, finding equivalents, literal interpreting, and strategic omission. Findings from this study offer valuable insights and practical guidance for learners and practitioners of simultaneous interpreting, enhancing their ability to manage CSIs more effectively and improve overall interpreting performance.
Comparing the cognitive Flexibility and Response Inhibition Abilities in Individuals with Mild Cognitive Impairment and Older Healthy Individuals
Authors: Aradhya Abhishek Budiguppe Panchakshari , - Rajasudhakar , Kashyap Ranjitha
Published: June 2024

Cognitive flexibility refers to the ability to switch rapidly between different responses sets. It is further sub divided into set shifting and cognitive shifting. While set shifting is considered to be automatic, cognitive shifting is considered to be conscious and strategic. Cognitive shifting can be assessed through a variety of linguistic and non-linguistic tasks. The non-linguistic tasks include stroop task, non-zero task etc. The alternating fluency task is a linguistic task, built in the same lines of generative naming. The only difference is that the participant has to rapidly alternate between two lexical categories in other words has to name a lexical item from first lexical category and then name a lexical item from the other lexical category. Response inhibition is the other executive function required for performing the alternating fluency task, as it would require the participants to inhibit the response belonging to the other lexical category. The current study was taken up with the aim of comparing cognitive shifting abilities in individuals with MCI and older individuals by employing alternating fluency task. Four lexical category combinations (animals-vehicles; birds-common objects; fruits-vegetables, colours and body parts) were considered and the task of participant was to name a lexical category from each combination (at once) within a period of 2 minutes. Each correct response was given a score of 1 when the participant could produce responses from both lexical categories given. 0 was given for partial and incorrect responses. Older participants performed better compared to participants with MCI. Individuals with MCI performed poorly as the cognitive flexibility and response inhibition are found to be compromised in these individuals.
DIFFERENCES IN MOTOR SKILLS BETWEEN SCHOOL-AGED GIRLS PRACTICING HORSEBACK RIDING AND THEIR NON-SPORTING PEERS
Authors: Ilić Predrag , Stojiljković Nenad , Stanković Nemanja
Published: June 2024

The study aimed to determine whether there are differences in motor skills between school-aged girls who ride and who do not ride, aged 12 to 14. The following motor skills were examined: balance, flexibility, limb speed, leg and body coordination, explosive and repetitive strength.Forty-nine respondents were divided into two subsamples, namely riders n = 26 and non-riders n = 23. To assess motor skills, the following tests were used: the Single and double leg stance test on a balance beam, Overhead stick rotation, the Forward bend twist and touch, Plate tapping and Foot tapping, the Japan test 5 x 4,5 m, 20 lunges with a pass under, the Standing broad jump, 2 kg medicine ball throw from a seated position, Sit-ups, Push-ups, and Squats.The distribution of the results was examined with the Kolmogorov-Smirnov test, and the difference in motor abilities was tested with the Mann-Whitney U test and the independent-samples T-test. The association between horseback riding and motor skills was examined using Pearson's and Spearman's correlation analyses. A significance level of p < 0.05 was accepted. The “Z” value was used to calculate the “r” value, and by calculating Eta squared and applying Cohen's d, the impact of horseback riding on the development of motor skills was analyzed.The results showed that there is a significant difference in motor skills between riders and non-riders. A moderate to strong correlation was found between riding and the examined motor skills. The impact of riding on the development of motor skills was detected ranging from moderate to large.
Los oficios del cronista
Authors: Coronado Eligio Moisés
Published: June 2024

Los menesteres del cronista han de ir más allá de la mera difusión de los acontecimientos del presente, que es para ser creíble su ocupación sustantiva, que para ser creíble debe mantenerse necesariamente ajena a todo afán turiferario, sino aún a dar a conocer los más remotos con criterio de valoración crítica, alentar los estudios historiográficos y su divulgación, participar en defensa y acrecentamiento de los bienes culturales, y originar, desde luego, su propia obra testimonial.
Tratamiento de paciente bruxista con restauraciones mínimamente invasivas: reporte de caso clínico
Authors: Vargas Santana Francisco , Guedea Preciado Nora Esther , Bayardo González Daniel Eduardo , Rodríguez-Chávez Jacqueline Adelina , Curiel González Ricardo , Magaña Curiel Karina
Published: June 2024

Introducción: el bruxismo es una condición oral asociada con numerosos problemas clínicos, se define como “hábito oral que consiste en rechinar o apretar en forma rítmica o espasmódica los dientes durante movimientos no masticatorios, lo cual puede ocasionar trauma oclusal”. Objetivos: presentar el seguimiento de un paciente con bruxismo de vigilia y del sueño, con pérdida de sustancia dental generalizada. Presentación del caso: se diagnosticó pérdida de sustancia dental generalizada asociada a bruxismo, así como dimensión vertical de oclusión disminuida. El tratamiento se dividió en 4 fases. Primera fase: Se tomaron modelos de diagnóstico, radiografías y fotografías. Segunda fase: Se evaluó el encerado mediante una maqueta de diagnóstico observando la armonía facial y aceptación del paciente. Tercera fase: Se prepararon las piezas, se tomó impresión final y se colocaron las restauraciones provisionales, las cuales se mantuvieron 2 semanas en boca para verificar la adaptación del paciente. Cuarta fase: Se cementaron las restauraciones finales y se colocó férula oclusal. El paciente tuvo una correcta adaptación a la nueva dimensión vertical de oclusión, se cumplieron los objetivos estéticos, biológicos y funcionales y se dio tratamiento a la parafunción. Conclusiones: las restauraciones mínimamente invasivas resultan ser una opción cómoda, rápida e indolora la cual cumple con los requisitos estéticos, biológicos y funcionales.
Corrección ortodóntica con camuflaje de paciente Clase III esquelética
Authors: Cantero-Becerra Rosa Yaneth , Mejía-Avalos Tania Elizabeth , Rodríguez-Chávez Jacqueline Adelina , Guerrero-Velázquez Celia , Rubio-Castillón Dora María , Meléndez-Ruiz José Luis
Published: June 2024

Introducción: uno de los principales problemas en ortodoncia con pacientes Clase III esqueletal es tomar la decisión de cómo llevar a cabo el tratamiento entre cirugía, o camuflaje ortodóntico con extracciones o sin extracciones. Paciente femenina de 13 años presenta Clase III esqueletal, mordida cruzada anterior, perfil recto, Clase I molar, Clase III canina izquierda subdivisión. Objetivos: mostrar el seguimiento ortodóntico de una paciente a la que se le realizó camuflaje ortodóntico de una Clase III esqueletal sin realizar extracciones. Presentación del caso: se utilizó aparatología con prescripción MBT 0.022″ y Essix con pista acrílica en el arco dental mandibular, para levantar la mordida y dar oportunidad de vestibularizar el sector antero-superior y corregir la mordida cruzada. Se inició con la fase de alineación y nivelación, seguido de arcos de acero. Se solicitó una ortopantomografía para verticalizar raíces y se finaliza con arcos trenzados y elásticos intermaxilares. Como resultado se corrigió la mordida cruzada anterior, se mantuvo el perfil recto, logramos Clase I molar y canina, y mejoró la sonrisa. Conclusiones: es posible lograr un exitoso camuflaje de una Clase III esqueletal siempre y cuando conozcamos los límites esqueletales, faciales, dentales y funcionales de cada paciente.
Actitud hacia el uso académico del ChatGPT de docentes en formación de República Dominicana
Authors: Taveras-Sánchez Berki Yoselin
Published: June 2024

Este artículo analiza la actitud hacia el uso académico del ChatGPT de docentes en formación de República Dominicana. Se administró un cuestionario en Google Forms, previamente validado estadísticamente y mediante juicio de expertos y pilotaje. El instrumento de 44 ítems se organizó en cuatro factores: beneficios referidos, desventajas referidas, prácticas de uso referidas y actitudes. La mayoría de los estudiantes tiene cuenta de ChatGPT y la ha usado para realizar trabajos académicos. Consideran que el ChatGPT proporciona asistencia personalizada e inmediata, mejora sus competencias, inteligencia y rendimiento. Tienen una actitud positiva hacia su uso como recurso pedagógico complementario. Sin embargo, el ChatGPT puede afectar el trabajo en equipo, la socialización, generar dependencia y propiciar prácticas académicas deshonestas. Las perspectivas estudiantiles podrían ayudar a educadores y diseñadores de políticas educativas a promover el uso ético, responsable, efectivo y regulado del ChatGPT en educación superior.
Formación docente y práctica pedagógica en la educación inclusiva: revisión sistemática
Authors: Gordillo Magdaly , Prado Víctor
Published: June 2024

Las demandas de atención que emergen en el marco de la diversidad funcional de los estudiantes son desatendidas y en la actualidad exigen fortalecer los procesos de formación docente. Esta revisión sistemática propone identificar los planteamientos actuales sobre formación docente y su incidencia en la práctica pedagógica desde la educación inclusiva. Se realiza un análisis cualitativo de publicaciones científicas entre el año 2019 al primer trimestre del 2024 mediante la metodología PRISMA, consultando Scopus, Science Direct y WoS. Tras la identificación, selección y cribado, se hallaron 43 artículos. Los resultados revelan que conceptos como didáctica, educación inclusiva y sensibilización del ser permiten que la formación docente impacte en la práctica pedagógica, teniendo como eje central la educación inclusiva. Este estudio sugiere investigar alrededor de la formación de maestros en ejercicio y se invita a explorar nuevas estrategias que promuevan una educación inclusiva en las aulas.
Hubungan antara Sikap Kerja dengan Musculoskeletal Disorders (MSDS) Pada Dokter Gigi di Rumah Sakit Gigi dan Mulut Saraswati
Authors: Dewa Made Candra Pramarta  , Ni Wayan Rusni  , Made Dharmesti Wijaya
Published: June 2024

Musculoskeletal disorders (MSDs) merupakan masalah pekerjaan yang sangat disorot di dunia. Sikap kerja adalah posisi tubuh pada saat melakukan aktivitas kerja dalam interaksinya dengan fasilitas kerja di stasiun kerja. Keluhan muskuloskeletal adalah keluhan pada bagian-bagian otot skeletal yang dirasakan oleh seseorang mulai dari keluhan yang sangat ringan sampai sangat sakit. Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara sikap kerja dengan MSDs pada dokter gigi di Rumah Sakit Gigi dan Mulut Saraswati. Jenis penelitian ini adalah penelitian analitik dengan rancangan cross sectional. Pelaksanaan penelitian dari bulan Maret hingga April 2022 menggunakan teknik pengambilan data simple random sampling dengan jumlah sampel sebanyak 60 responden. Data diukur dengan menggunakan Nordic Body Map (NBM) untuk MSDs dan kuesioner Rapid Entire Body Assessment (REBA) untuk postur Kerja. Data dianalisis menggunakan SPSS 25. Hasil analisis univariat menunjukkan sebagai berikut : risiko postur kerja dan kategori MSDs masing-masing sebesar 50% (sedang) dan 43,3% (berat), sedangkan analisis bivariat menggunakan uji Spearman Rank menunjukkan skor p < (0,05) dengan nilai r = 0,83. Dapat ditarik kesimpulan bahwa ada hubungan yang signifikan antara postur kerja dengan MSDs. Direkomendasikan bahwa postur kerja dokter gigi harus pendekatan ergonomis.
Pengaruh Pemberian Tepung Kulit Nanas Terfermentasi Dalam Ransum Terhadap Komposisi Fisik Karkas Ayam Kampung Super
Authors: Yeremias koa  , Yan Tonga  , I Gusti Ayu Dewi Seri Rejeki
Published: June 2024

Kebutuhan produk makanan bergizi terutama produk makanan asal hewani saat ini terus mengalami peningkatan. Untuk mencapai produktivitas ini harus di dukung oleh pakan yang berkualitas salah satunya memanfaatkan limbah kulit nanas terfermentasi. Tujuan dari penelitian ini untuk mengetahui pengaruh pemberian tepung kulit nanas terfermentasi terhadap komposisi fisisk karkas ayam kampung super umur 10 minggu. Rancangan yang digunakan dalam penelitian ini adalah Rancangan Acak Lengkap (RAL) dengan 5 perlakuan dan 3 ulangan. Adapun perlakuan yaitu N0= Ransum tanpa kandungan tepung kulit nanas terfermentasi, N1= Ransum mengandung 5% tepung kulit nanas terfermentasi, N2= Ransum mengandung 10% tepung kulit nanas terfermentasi, N3= Ransum mengandung 15% tepung kulit nanas terfermentasi, N4= Ransum mengandung 20% tepung kulit nanas terfermentasi. Hasil penelitian menunjukan bahwa tidak terjadi pengaruh yang signifikan (P>0,05) kecuali pada perlakuan N0 berbeda nyata (P<0,05) dengan penambahan kulit nanas terfermentasi dalam ransum terhadap komposisi fisik karkas ayam kampung super 10 minggu. Pemberian tepung kulit nanas terfermentasi pada level 5% menunjukan hasil rataan yang paling baik terhadap komposisi fisik karkas ayam kampung super umur 10 minggu kecuali pada perlakuan N0 berbeda nyata. Dari hasil penelitian dapat disimpulkan bahwa Pemberian tepung kulit nanas terfermentasi dalam ransum berpengaruh tidak nyata terhadap komposisi fisik karkas (berat daging paha, berat kulit paha, berat daging dada, berat tulang dada, berat kulit dada kecuali berat tulang paha pada perlakuan N0 berbeda nyata) ayam kampung super 10 minggu.
Pengolahan Buah Kelapa Menjadi Serundeng Sebagai Upaya Pemanfaatan Potensi Alam Desa Ban, Karangasem
Authors: - Gek ayu sagita widya tresna wati , Sang Ayu Made Agung Prasetiawati Djelantik  , Gusti Ngurah Oka Jiwantara
Published: June 2024

Desa Ban, Kubu, Karangasem mempunyai keunggulan pada potensi alam yang dimiliki, yaitu pohon kelapa. Potensi alam berupa pohon kelapa di Desa Ban, Kubu, Karangasem belum dioptimalkan secara maksimal karena mayoritas masyarakat hanya memanfaatkan dengan menjualnya dalam bentuk buah kelapa, belum dijadikan produk unggulan pangan yang mampu meningkatkan nilai potensi ekonomi masyarakat desa tersebut. Tujuan dilaksanakan pengabdian ini adalah agar masyarakat bisa memanfaatkan potensi alam yang ada di desa Ban, Kubu, Karangasem agar dapat bernilai ekonomi dengan harapan kedepannya potensi alam tersebut dapat dijadikan produk unggulan pangan yang mampu meningkatkan nilai potensi ekonomi masyarakat desa Ban, Kubu, Karangasem. Kegiatan pengabdian ini berhasil menarik perhatian pemerintahan dan masyarakat Desa Ban, Kubu, Karangasem.
Pengaruh Zat Pengatur Tumbuh Atonik Dan Pupuk Bokasi Terhadap Pertumbuhan Dan Hasil Tanaman Tomat (Solanum lycopersicum L.)
Authors: I Komang Sujana  , Made Suarta  , Ketut Agung Sudewa
Published: June 2024

This study aims to determine the interaction of Bokasi Fertilizer and Atonic Growth Regulators on the growth of tomato plants. This research was conducted in the greenhouse of the Faculty of Agriculture, Warmadewa University, JI. Ompong 24 Tanjung Bungkak, Denpasar with a height of 25 m above sea level. This research starts from August - October 2023. This experiment uses a factorial pattern Group Randomized Design (RAK) with two factors, namely: Factor I is atonic ZPT with 4 levels of concentration, namely: A0 = 0 cc 1-1, A1 = 1 cc 1-1, A2 = 2 cc 1-1, A3 = 3 cc 1-1, Factor II is bokashi fertilizer consisting of 4 concentrations, namely: B0= 0 tons / ha, B1 = 10 tons / ha,  B2 = 20 tons / ha, B3 = 30 tons / ha, Thus there are 16 combination treatments, each of which is repeated 3x so that there are 48 experimental polybags. The treatment of atonic growth regulators 1 cc 1-1 tends to give the highest dry weight yield of 148.68 grams, which is not real from other treatments. The treatment of 30 tons / ha of bokasi fertilizer tends to produce the highest dry weight of 149.44 grams which is not real from other treatments. Bokasi fertilizer has a real effect (P<0.05) on the fruit diameter and no real effect (P>0.05) on other variables. The treatment of bokasi fertilizer of 30 tons / ha produces the highest fruit diameter of 3.49 cm which is not real with the treatment of fertilizer 0 tons / ha and 20 tons / ha with fruit diameters of 3.31 cm and 3.40 cm respectively, but differs markedly from the application of bokasi fertilizer of 10 tons / ha with a fruit diameter of 3.10 cm. Bocation fertilizer tends to show no real influence on the growth and yield of tomato plants which is likely due to goat manure bokashi fertilizer has not been absorbed by tomato plants optimally.
Evaluating Curcumin Intake on Metabolism-Related Genes in Drosophila melanogaster
Authors: Halim Jonathan Elbert Karsten , Asbah Asbah , Latada Nadila Pratiwi , Mudjahid Mukarram , Usmar Usmar , Yulianti Risfah , Nainu Firzan
Published: June 2024

Background Aging entails a gradual deterioration of physiological functions within the body. Current research provides evidence suggesting that curcumin may extend the lifespan of fruit flies by mitigating the effects of aging. However, the precise concentration of curcumin necessary to induce favorable phenotypic and molecular outcomes in fruit flies has yet to be determined.
Method The study utilized the capillary feeder (CAFE) assay on male Oregon-R flies, and examined the expression of the srl and pepck genes through the reverse transcriptase quantitative PCR (RT-qPCR) method.
Case An elevation of curcumin consumption was examined in the treatment groups that were provided with feed containing curcumin concentrations of 50 Î¼M and 250 Î¼M. This observation is consistent with the increased lifespan noted in the Drosophila groups consuming higher concentrations of curcumin. Meanwhile, molecular analysis at the expression level of the srl and pepck genes revealed no significant change in gene expression between the treatment and control groups.
Conclusion The use of the CAFE assay assists researchers in quantitatively measuring the amount of curcumin intake in Drosophila melanogaster. However, the consumption of curcumin in this experiment did not demonstrate a significant impact on the metabolism-related genes of Drosophila, srl and pepck genes.
EFFECTS OF ALUMINUM FIBERS ADDITIVE ON THE COMPRESSIVE STRENGTH OF A CONCRETE
Authors: Sudirman Indra  , Nadya Rachma  , Mohammad Erfan  , Endro Yuwono  , Ratri Andinisari
Published: June 2024

Utilizing recycled waste as an additional construction material is an innovation that can reduce the negative environmental impacts caused by waste. One of the wastes that can be utilized in this case is aluminum cans. The use of aluminum fiber in concrete mixtures is appropriate since aluminum is resistant to corrosion or rust. This research aims to determine the effect of adding aluminum fiber on the compressive strength of concrete. The aluminum cans were shaved into fibers with dimensions of 2 x 35 mm. The resulting aluminum fiber is then added into the concrete mixture with a percentage of 0%, 0.05%, 0.075%, 0.1%, and 0.125% of the total volume of the test objects. Tests for compressive strength was then carried out after test specimens were aged for 28 days. The test results showed a peak compressive strength of (20.72 ± 0.35) MPa is observed at the addition of 0.05% aluminum fiber relative to the volume of concrete used for testing. A regression analysis was performed based on the relationship between the amount of aluminum fiber additive and the resulting compressive strength. Based on this analysis, the optimum value for aluminum fiber to be added to the concrete is 0.040% of its volume.
ENVIRONMENTAL ANALYSIS ON SOFT CLAY SOIL STABILIZATION AS A SUBGRADE IN BINJAI – PANGKALAN BRANDAN TOLL ROAD PROJECT
Authors: I Made Kusuma Wiranata  , I Nengah Sinarta  , Putu Ika Wahyuni
Published: June 2024

Soft soil poses significant challenges in road construction projects, particularly in the Binjai - Pangkalan Brandan Toll Road, where non-uniform settlement of landfills has been observed. To address these issues and achieve the desired subgrade quality and compression, various soft soil stabilization methods have been employed, including mechanical approaches such as Prefabricated Vertical Drain (PVD) with preloading or vacuum and Pile Embankment. This study aims to evaluate the environmental impact of these three stabilization methods using the Strength, Weakness, Opportunities, and Threats (SWOT) method. Primary data was collected through interviews with experts from diverse stakeholders, including academics, planning consultants, and implementing contractors, using the purposive sampling technique. Focus Group Discussion (FGD) was conducted to develop SWOT strategies for each repair method based on environmental assessment indicators derived from literature studies. The SWOT analysis results indicate that the PVD Preloading method is the most environmentally friendly among the three methods. This is attributed to the absence of cement usage, lower electrical energy consumption, and the use of more environmentally friendly materials. Although PVD Preloading requires additional backfill for the preloading process, the impact on the environment is minimal, as the soil material used comes from the project site, and approximately 90% of the backfill is returned as road backfill after the consolidation process is complete. The analysis also reveals that the speed of the consolidation process is inversely proportional to its environmental friendliness.
Peranan Desa Adat Dalam Upaya Filterisasi Budaya Guna Melestarikan Pariwisata Budaya Di Desa Adat Legian, Kabupaten Badung
Authors: Diah Gayatri Sudibya  , Kade Richa Mulyawati  , Putu Ayu Sintya Pradnya Dewi  , I Dewa Ayu Diah Permatasari
Published: June 2024

Bali yang mempunyai nilai jual di bidang pariwisata memperkenalkan konsep wisata budaya dalam Peraturan Daerah Bali Nomor 5 Tahun 2020 tentang Standar Penyelenggaraan Pariwisata Budaya Bali tepatnya pada Pasal 1 Angka 12 yang menyatakan bahwa â€œWisata budaya Bali adalah Wisata Budaya Baliâ€. pariwisata berbasis budaya Bali yang dijiwai oleh filosofi Tri Hita Karana yang bersumber dari nilai budaya dan kearifan lokal Sad Kerthi serta berlandaskan Taksu Baliâ€. pariwisata berbasis budaya Bali harus berorientasi pada kualitas, sehingga diperlukan penataan yang komprehensif sesuai dengan visi pembangunan daerah Bali dan juga berorientasi pada keberlanjutan dan daya saing yang juga memerlukan standar penyelenggaraan pariwisata berdasarkan Tri Hita Karana. Perkembangan di Bali terlihat perubahan yang sangat besar, mengingat Bali merupakan destinasi wisata favorit dan juga salah satu pulau idaman yang ingin ditinggalkan oleh wisatawan baik domestik maupun mancanegara. Hal ini mengakibatkan krama (warga) desa yang tinggal di Bali tidak lagi hanya dihuni oleh krama (warga) asli Bali yang mempunyai ciri-ciri homogen tetapi telah berubah menjadi masyarakat yang heterogen. Hal ini tentunya menambah suku, ras dan agama bahkan negara yang memiliki komunitas atau krama berbeda yang tinggal di Bali. Dampaknya juga bisa menjadi pintu masuk budaya asing karena banyaknya wisatawan asing yang tinggal dan kesehariannya di Legian. Hal ini apabila tidak mendapat perhatian khusus dan tidak ada upaya penyaringan atau penyaringan budaya maka dikhawatirkan dapat merusak budaya asli Bali yang dipertahankan selama ini. Hal ini juga akan berdampak pada keberlangsungan wisata budaya yang dicanangkan pemerintah Bali.
Pengaruh Pendapatan Dan Lingkungan Sosial Terhadap Minat Menabung Mahasiswa Pada Bank BRI
Authors: Ruhamak Muhammad Dian , Dewandaru Bothy , Andriani Nabila , Zalviana Ridha , Listiyaningrum Isro’in , Cahyani Risma Gesang Ayu , Jorumana Deni Umbu Siwa
Published: June 2024

Penelitian ini bertujuan untuk menganalisis seberapa besar pengaruh pendapatan dan lingkungan sosial terhadap minat menabung di kalangan mahasiswa kelas reguler pagi di Fakultas Ekonomi dan Bisnis Universitas Kadiri. Penelitian kuantitatif ini menggunakan data primer yang diperoleh melalui observasi, wawancara, dan penyebaran kuesioner. Sampel yang digunakan dalam penelitian ini sebanyak 50 responden. Teknik analisis data yang digunakan adalah Uji Validitas dan Uji Reliabilitas, Uji Analisis Regresi Linier Berganda, dan Uji Hipotesis (Uji t, Uji F, dan Uji Koefisien Determinasi (R2)). Berdasarkan hasil pengujian diperoleh hasil bahwa variabel Pendapatan memiliki pengaruh yang signifikan terhadap variabel Minat Menabung, variabel Lingkungan Sosial memiliki pengaruh yang signifikan terhadap variabel Minat Menabung, variabel Pendapatan dan variabel Lingkungan Sosial memiliki pengaruh yang signifikan terhadap variabel Minat Menabung. Variabel Pendapatan dan Lingkungan Sosial berpengaruh sebesar 36,3% terhadap variabel Minat Menabung, sedangkan faktor lain diluar penelitian ini berpengaruh sebesar 67,7% sisanya.
Implementation of the Plate Meal Method towards Self-Management of Type 2 Diabetes Mellitus Patients
Authors: Alda Rauza , Mulfianda Riyan , Desreza Nanda
Published: June 2024

Plate meal is a diet therapy program for Diabetes Mellitus Type 2 patients, which may balance the blood glucose by dividing food on the plate. Improving patient self-management may difference the patients, especially those with Diabetes Mellitus type 2. This research aimed to determine the difference of the plate meal method with diet program implementation toward self-management among patients with Diabetes Mellitus type 2. This research was a quasi-experiment with pre and post-test equivalent control group methods. The population of this research was thirty patients with Diabetes Mellitus type 2 in Ulee Kareng Regional Technical Implementation Unit Health Community Center of Banda Aceh, which was divided into two groups, consisting of 15 respondents from the intervention group and 15 from the control group. The technique used in taking the samples was purposive sampling. This research was conducted in Ulee Kareng Regional Technical Implementation Unit Health Community Center from June 19 to 27, 2023. The data analysis used was a paired t-test and an independent t-test. The result of the research showed that the p-value of the paired t-test on the intervention group was 0.002. Therefore, there was a difference. The p-value of the control group was 0.369, which showed that there was no difference toward the control group, while the p-value of the independent t-test was 0.047 (p-Value ? 0,05), indicating that there was an difference between the intervention and control group after the treatment of the intervention group. The conclusion of this study is that there is a difference in the application of the plate meal method diet program towards self-management in Type 2 DM patients at the UPTD Ulee Kareng Community Health Center, Banda Aceh between the control and treatment groups.
Angiography Scores Can Predict Amputation in Diabetic Feet
Authors: Gede Budhitresna Anak Agung , Anak Agung Gede Agung Budhi Kesuma  , Ketut Putu Yasa
Published: June 2024

Diabetic foot is a complication of diabetes mellitus, with a risk of amputation. One of the risk factors for amputation is peripheral arterial occlusive disease. Angiography is a diagnostic method used to visualize blood vessels, plan therapeutic actions, and predict prognosis, including the likelihood of amputation. The validity of angiography scores in predicting amputation in diabetic foot patients is assessed. This study is a diagnostic test to determine the validity of angiography scores in predicting amputation in 23 diabetic foot patients at Prof. Dr. I.G.N.G. Ngoerah General Hospital. Data analysis used the Receiver Operator Curve (ROC) and diagnostic tests to obtain the Area Under the Curve (AUC), cutoff point, sensitivity and specificity, Negative Predictive Value (NPV), Positive Predictive Value (PPV), Positive Likelihood Ratio (PLR), and Negative Likelihood Ratio (NLR). The study results showed a cutoff point for angiography scores of 33% with an AUC of 0.9841 (>0.7) for the percent score and a cutoff point of 6 with an AUC of 0.9960 for the total score (>0.7). The sensitivity and specificity of the angiography scores were very good for predicting amputation in diabetic foot, at 92.9% and 88.9% (CI 95%), respectively. With PPV of 92.9% and NPV of 88.9%, the diagnostic value of angiography scores in predicting amputation in diabetic foot patients is supported. This study shows that angiography scores have good validity in predicting amputation in diabetic foot patients.
KARET ALAM PADA KONDISI SUNSET INDUSTRI?
Authors: Tistama Radite
Published: June 2024

Agribisnis karet nasional tengah mengalami tekanan berat dalam satu dekade ini disebabkan melemahnya harga karet. Beberapa tahun tekahir kondisi perkebunan karet mendapat tambahan beban dengan outbreak serangan penyakit gugur daun yang dapat menurunkan produktivitas karet. Kondisi tersebut memacu pesimisme pelaku bisnis karet dari petani karet, perkebunan karet dan prosesor yang direspon dalam bentuk konversi perkebunan karet ke komoditas lainnya. Review ini mengulas berbagai perkembangan industri hilir karet alam global dan nasional dan kondisi hulu perekbunan karet. Perkembangan hilir karet alam terus meningkat yang ditunjukan terus membaiknya bisnis produk-produk berbahan baku karet alam seperti ban, alas kaki, ban vulkanisir, alat-alat medis dan lain sebagainya. Selain itu perkebunan karet juga yang berperan dalam menyerap karbon sangat potensial masuk pasar karbon yang bursanya sudah dibuka. Berbagai kebijakan perlu buat dan diimplentasikan untuk menguatkan pendanaan peremajaan perkebunan karet, serapan teknologi karet domestik dan menarik investor industri hilir karet. Sinkronisasi peta jalan di hulu dan hilir karet mendesak untuk menjaga keberlanjutan suplai dan permintaan. Semakin tinggi serapan domestik akan menberikan dampak membaik penyerapan tenaga kerja lokal dan bergairahnya kembali perkebunan karet.
Some observation made for Lkhagva Jagdal’s translation
Authors: Ts Magsar
Published: June 2024

Жагдалын Лхагвын 80 насны ойд зориулсан энэхүү өгүүлэлд орос хэлнээс орчуулсан зарим зохиолуудад нь ажиглалт хийж орчуулагчийн хэрэглэж байсан түгээмэл арга, хувиргалын онцлогийг жишээ баримтад тулгуурлан тайлбарлав. Тухайлбал, утга тодруулж орчуулах, тэр дундаа утга дэлгэрүүлэх ба ялгаруулах, чимэг нэмэх, өөрийн дүрслэлээр баяжуулах, мөн утга ерөнхийлжорчуулах, утга тонгоруулжорчуулах зэрэгаргыг тэрээр орчуулгадаа нийтлэг хэрэглэдэг байжээ.
The state and features on Chinese translations of Mongolian literature
Authors: Sh Egshig
Published: June 2024

Монгол уран зохиолыг хятад хэлээр орчуулах үйл явц бүр Хүннүгийн үеэс ч эхэлсэн байх магадлалтай. Дундад зууны үед буюу Юань улсын үед орчуулгын ажил идэвхтэй өрнөж, бүр орчуулгын ажил эрхэлсэн хороо хүртэл байгуулагдаж байсан юм. Монгол зохиол хятад хэлнээ орчуулагдаж байсны нэг тод жишээ бол Монголын нууц товчооны бүлгийн хятад орчуулга болон үг бүрийн ард хадсан хадмал орчуулга гэж үзэх үндэслэл бий. Монголын шинэ үеийн уран зохиолын хятад хэлээрх орчуулгын ажил XX зууны дунд үеэс эрчимтэй хөгжсөн гэж үзэж болно. Эдүгээ XXI зуунд орчуулгын ажил зохих хэмжээнд үргэлжилж байгаа ч, монгол үндэстний уран зохиолын орчуулгын ажил сүүлийн жилүүдэд ӨМӨЗО-ны орчуулагчдын нийгэмлэгийн цөөнх үндэстний уран зохиолын орчуулгыг дэмжих бодлогын хүрээнд харьцангуй идэвхтэй өрнөж байгаа дүр зураг ажиглагдаж байна.
The translation of Mongolian verses with their “melodic” onomatopoeic rhythms and tones
Authors: D Dolgorsuren
Published: June 2024

This paper will focus on the translation of Mongolian verses of poetry into English and its main features. The translation is an activity that aims at conveying the meaning or meanings of a given linguistic discourse from one language to another. We define translation in terms of the sameness of meaning across languages. One of themost significant features of the Mongolian verses is their alliteration and assonance and their “melodic” onomatopoeic rhythms or tones in their lines, word numbers, and whether or not they are stressed or unstressed in certain syllables. Overall, when we translate the alliteration of Mongolian verses into other languages, specifically into English, we write them expressing their meanings in the same letters that each last word in the lines has. The main aim of this article is to compare and do some analysis of a verse named “A mountain peak” by Yavuukhulan Begz, one of the best poets in Mongolia.
Iconopoeic Words in Mongolian and Expressing their Meaning in English
Authors: S Dugarmaa , A Amarzaya , B Oyunsaikhan
Published: June 2024

The article aims to introduce a survey of Mongolian literary works that have been translated from Mongolian into English by both Mongolian and foreign translators. Iconopoeic (form-depicting) Words are a literary tool, as can be seen in the works of Mongolian writers. We have tried to show how iconopoeic (form-depicting) words in Mongolian, especially verbs, are expressed in English in the examples of Mongolian literary translations. Examples are taken from translations by our famous translators, and conclusion was made based on the translation examples. It has been observed that iconopoeic (form-depicting) words were translated using free translation in Mongolian literature, especially in Mongolian prose and also these words were often omitted in the context.
Some issues on the translator and interpreter’s competences
Authors: G Bat-Uchral , V.I Pavlov
Published: June 2024

Due to the current situation, learning a foreign language has become a necessity for everyone. As a result, everyone who speaks a foreign language is daily facing with the situation to do the translation if necessary. This raises the issue of translation quality, which is directly or indirectly related to the translator's knowledge and reception and production competences of the mother tongue and the target language. Linguistic competence is an important part of a translator's linguistic knowledge, and this time we have analyzed how linguistic competence is reflected in the Common European Framework of Reference for Languages: Learning, Teaching and Assessment.
A study on translation of culture-specific realia in Mongolian novel
Authors: Ch Zolzaya
Published: June 2024

This study analyzes how the culture-specific items (words and phrases) of the Mongolian language have been translated into English based on literary examples. The translation of the culture-specific word is unique and difficult for foreigners to understand because it is inextricably linked with the language, culture, and customs and reflects the national characteristics. As a result of this research, the author has analyzed the literary translation of culture-specific words (realia), especially how culture-specific words in literature were translated from Mongolian into English. The study was done based on the selected Mongolian novel. During the research work, some culture-specific words were left untranslated, and in some cases, one word was translated in many different ways. In addition, there are cases where the original text's eloquent, historical, and cultural examples were omitted during the translation process. Therefore, this work will contribute to the promotion of our national heritage and researchers researching this topic.
About translation skills of T.Galsan, the Honored People’s Writer of Mongolia (On the example of Mongolian translation of the novel “Ion” by Liviu Rebreanu)
Authors: E Batjavkhlan
Published: June 2024

This article analyzes the Mongolian translation of the novel "Ion" by the famous Romanian writer Liviu Rebreanu. The Mongolian translation of this novel was made by a duet of translators T. Galsan and B. Chimiddorzh, published in the State Publishing Department in Ulaanbaatar in 1988. Using several examples, the author of the article analyzes in detail the features of the Mongolian translation, comparing them with the Romanian original of the novel, evaluating the work of translation as an example of a good innovative translation, where the ways of conveying the creative work of the Romanian writer were thoroughly studied and implemented, and translated into the Mongolian language, taking into account the features mentality of Mongolian readers. The author also criticizes the fact that many good Mongolian translations of the second half of the twentieth century still remain outside the attention of researchers, one of such invaluable translation publications is the translation work of the famous Mongolian writer T. Galsan. Over the past few years, many literary translations have been published in Mongolia, but in addition to the quantity, the quality of translations is clearly deteriorating due to the increasingly widespread processed machine translations. Therefore, the author of the article also calls for studying the creative experience of translations of older generations, as an example of reference translation works.
Alexander Romance in Central Asia
Authors: J.A. Boyle
Published: June 2024

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