bluuebunny/crossref_metadata_2025 huggingface dataset:
L’anxiété du patient en situation de maladie grave : la réponse palliative
Authors: Mboua Pierre Célestin , Nguepy Keubo François Roger , Bianke Patrice
Published: October 2018

L’anxiété dans l’attente d’une opération chirurgicale peut s’avérer préoccupante pour la réussite de l’intervention et l’intégrité psychique du patient. Cet article porte sur un cas clinique dont le suivi psychosocial s’est fondé sur le modèle de prise en charge intégrée. L’observation du patient au cours du suivi a mis en évidence un vécu anxieux envahissant. Dans ce contexte, la compétence du patient a été un facteur anxiogène majeur. Il a été mis en évidence le fait que dans une intervention chirurgicale relative à une maladie grave et/ou chronique, « le savoir » du patient, réputé « auxiliaire » de santé peut devenir un facteur de contrainte qu’il faut intégrer dans la réponse globale. Le cas étudié permet de poser les jalons d’un modèle de réponse palliative intégrée dans cette prise en charge qui valorise la notion de compétence du patient.
La spiritualité dans la pratique infirmière : une démarche
Authors: Matter Puons Gabriela , Flückiger Véronique , Meier Hans Ruedi , Pralong Gérard
Published: October 2018

Si les définitions des soins palliatifs et la littérature soignante intègrent la spiritualité, il est légitime de se questionner sur la place réservée à celle-ci dans la pratique professionnelle infirmière. Cet article met en évidence la démarche réalisée dans l’unité de soins palliatifs de l’Hôpital de Lavaux visant à intégrer la spiritualité dans les soins. Ce travail a été conduit en partenariat avec les professionnels du terrain, mais également avec les patients. Nous avons identifié différentes formes de spiritualités ainsi que les freins entravant leur expression. La démarche a abouti à l’introduction d’un outil de recueil de données adapté, nommé HOPE.
Conjoncture économique et système bancaire en Afrique. Cas du Maroc
Authors: Machrafi Badr
Published: October 2018

Le système bancaire a retenu depuis longtemps l’attention des économistes suite à la place et au rôle joués sur le plan économique et social. Ainsi, les crises financières au cours des vingt dernières années ont relancé les recherches relatives à la compréhension de l’origine du monde opératoire des cycles de l’activité économique. Dans ce sens, les travaux qui se sont intéressés à l’étude de la relation entre la conjoncture économique et le système bancaire, introduisent plusieurs facteurs qui nous ramènent à d’autres théories relatives aux concepts de capital social, psychologique et à prendre en compte de la situation du système économique et l’ouverture de système financier. L’objectif de notre étude empirique est de contribuer à l’étude de l’impact de la conjoncture sur le système bancaire marocain. Nous avons adopté une méthodologie quantitative pour mener à bien notre recherche, utilisant des méthodes économétriques afin de répondre à notre objectif d’étude. Les résultats empiriques obtenus nous ont permis de constater que la conjoncture et le système bancaire sont liés par les relations de causalité au sens de Granger à court terme. En revanche, l’application d’autres tests nous n’a pas permis de conclure qu’il existe une relation entre la conjoncture économique et le système bancaire pour le cas marocain. Ainsi, selon les résultats obtenus à partir des tests effectués, notre étude empirique ne valide pas la relation reliant le système bancaire et la conjoncture économique exprimée par les variables traitées et retenues.
La prise en compte des émotions dans le comportement des actionnaires individuels minoritaires
Authors: Darras-Barquissau Nathalie
Published: October 2018

Le décryptage du comportement des actionnaires individuels par une mesure de leurs émotions peut être un atout pour les entreprises cherchant à assurer leur pérennité à long terme. Ainsi notre objet de recherche s’articule autour de deux types d’émotions avec d’une part les émotions liées à la nature même de l’individu (l’appétence vis-à-vis des marchés financiers et l’optimisme), d’autre part les émotions potentiellement ressenties vis-à-vis des sociétés dont ils détiennent les titres (l’attachement et la familiarité). Après avoir fait état d’une revue de littérature permettant la formulation d’items, nous proposons de vérifier la fiabilité des échelles, effectuée grâce au calcul du coefficient alpha de Cronbach et à l’évaluation de l’unidimensionnalité des échelles grâce à une analyse factorielle exploratoire.
Étude de la complémentarité entre le BSC et SCOR
Authors: Lepori Elvia , Bollecker Marc
Published: October 2018

Les nombreuses études consacrées au Balanced Scorecard (BSC) depuis vingt ans ont cherché à le faire évoluer et à l’enrichir pour l’adapter à des contextes variés. Parallèlement, d’autres systèmes de mesure de la performance se sont développés, à l’instar de SCOR applicable à la Supply Chain, qui posent la question de leur complémentarité avec le BSC. Après l’analyse théorique des deux modèles et de leur complémentarité, l’article expose la méthodologie et les résultats d’une recherche intervention, réalisée auprès d’un prestataire de services logistiques français utilisant un BSC et qui souhaitait implanter SCOR.
Sortir de la bulle et entrer dans le rond d’un premier cercle social
Authors: Vamos Julianna
Published: October 2018

Il est proposé toutes les semaines, à la maternité des Bluets, à Paris, un atelier de rencontre pour les parents et leur nouveau-né : « Hello Baby ! Mais comment naissent les parents ». Pendant leur séjour, les parents sont invités à présenter leur bébé, à échanger autour de leur accouchement et de leur expériences émotionnelles : leur désarroi, leur émerveillement dans la rencontre avec leur bébé. Se tissent alors dans une atmosphère conviviale une écoute groupale et sociale des différents récits de leur vécus. Certaines thèmes émergent régulièrement et résonnent collectivement : la fatigue, le sentiment de solitude, le fantasme de perfection parentale et la culpabilité qui lui est associée.
Aspects hormonaux du post-partum et ostéopathie
Authors: Namer Valérie
Published: October 2018

Comprendre la physiologie des variations hormonales du post-partum ainsi que les facteurs pouvant l’influencer est un enjeu important de l’accompagnement après la naissance. La mère et l’enfant vivent un sevrage hormonal brutal au moment de la délivrance quand le placenta cesse de remplir son rôle endocrinien. S’organisent alors des sécrétions hormonales sous la dépendance de la stimulation réciproque de la mère et l’enfant. Ces phénomènes vont être renforcés par un environnement soutenant. Les ostéopathes sont des intervenants de première ligne en périnatalité et peuvent améliorer la prise en charge du bien-être postnatal.
« Bébé Trucs »
Authors: Breton Joanne
Published: October 2018

Une formule très simple et conviviale : « Bébé Trucs » est une activité gratuite, ouverte sans rendez-vous aux parents d’enfants entre 0 et 2 ans de Sherbrooke (Québec) et des environs, tous les mercredis entre 13 heures et 16 h 30. Les professionnelles de santé sont sur place pour répondre aux préoccupations des parents, suivre le développement de leur tout-petit, les soutenir pour l’allaitement au besoin, etc.
La technicienne de l’intervention sociale et familiale… au cœur du quatrième trimestre de la grossesse
Authors: Clochard Jean-Laurent
Published: October 2018

La tisf est une professionnelle du champ de l’accompagnement à la parentalité. Elle intervient au domicile des parents, par exemple, confrontés aux troubles relationnels mère-bébé. Elle s’inscrit dans une démarche préventive de soutien des parents dans tous les actes de la vie quotidienne, de valorisation les compétences parentales et familiales, et d’observation fine des interrelations entre le bébé et sa maman. Encadrée par un responsable de secteur, en contact régulier avec les professionnels de la santé, son action bénéficie de dispositifs publics d’aide à domicile, nationaux et/ou locaux.
L’accompagnement postnatal par le shiatsu
Authors: Froc Fanny
Published: October 2018

Le shiatsu est un art du toucher qui soutient la personne vers une harmonie Corps/Esprit. Il n’est pas uniquement destiné à la maternité, mais son application à cette période féminine si singulière et bouleversante est largement recommandée. Au travers de son histoire puis de son fonctionnement, tous les bienfaits de cette pratique japonaise multimillénaire en période postnatale sont évoqués. Le shiatsu sait lier les connaissances ancestrales asiatiques avec les physiologie et psychologie modernes, ainsi que tous les savoirs actuels sur l’importance d’un accompagnement précoce et naturel de la femme et de son bébé.
La période postnatale dans les traditions des peuples méso-américains
Authors: Corne Eugenia
Published: October 2018

L’auteur, chercheuse autodidacte sur la culture maya préhispanique et contemporaine, présente les grandes lignes de la conception maya à l’égard de la période postnatale, sur les plans spirituel et prophylactique.
Le rebozo, témoin des passages de la vie d’une femme
Authors: Doyon Alexandra
Published: October 2018

Le soin rebozo doit son nom à une écharpe tissée qui accompagnait traditionnellement les femmes tout au long de leur vie dans les pays d’Amérique latine. Il constitue un ensemble de pratiques qui, au sein d’un espace sacré d’accueil et d’attention, marque et célèbre les grandes étapes de la vie féminine.
Au jour le jour : un quatrième trimestre « prématuré » ?
Authors: Bertrand Clotilde
Published: October 2018

La naissance prématurée est une effraction dans la vie d’une famille. Avec la prématurité, l’échelle du temps est bouleversée, les représentations familiales du bébé modifiées. L’onde de choc qu’elle provoque est contenue par le savoir-faire des professionnels qui, observant et écoutant les bébés et leurs parents, leur laissent le temps de développer leurs compétences.
Equites del ala Tauriana al servicio de Roma: los Sempronii del oppidum de los bañales (Hispania Citerior)
Authors: Ventura Villanueva Ángel , Andreu Pintado Javier , Romero Novella Luis
Published: October 2018

Analizamos, desde una perspectiva prosopográfica, la carrera militar desarrollada a comienzos de época imperial en el ala Tauriana y en la cohors Germanorum por Q. Sempronius Vitulus, oriundo de la ciudad hispanorromana de Los Bañales de Uncastillo (Hispania Citerior). Él y su padre, L. Sempronius, constituyen ejemplos palpables del papel del ejército en el proceso de integración de las élites indígenas en la sociedad romana y del protagonismo de éstas en las transformaciones urbanísticas y la monumentalización de sus ciudades de origen.
La artillería en el reino de Castilla y León durante el siglo XV
Authors: De Castro Fernández José Javier , Mateo de Castro Javier
Published: October 2018

La artillería del reinado de Juan II y Enrique IV ha sido tradicionalmente dejada de lado frente al gran desarrollo acontecido en este ámbito durante el gobierno de los Reyes Católicos. Sin embargo, el análisis de las políticas puestas en marcha por el padre y el hermanastro de Isabel en el trono castellano muestra un gran número de avances en la fabricación y uso de las armas artilleras, hecho que permite comprender los logros posteriores. Además, la historiografía tradicional no abordó el papel jugado por los poderosos nobles castellanos del siglo XV, emitiendo por ello un juicio sesgado sobre la artillería de aquel momento.
An Eight-Layer Model for Mathematical Cognition
Authors: Pappas Marios A. , Drigas Athanasios S. , Polychroni Fotini
Published: October 2018

In recent years, more and more researchers have been investigating mathematical knowledge, as well as the cognitive skills that seem to be related to the improvement of mathematical thinking, numerical skills, mathematical logic and problem solving techniques. In this paper, we present the cognitive processes that are related to mathematical performance, such as working memory, anxiety, attention, spatial cognition, executive function and phonological awareness. In addition, we refer to metacognitive skills and their role in controlling and regulating cognitive processes, in order to improve mathematical performance. Finally, we present a new taxonomy of mathematical skills, the pyramid of mathematical cognition, as well as their gradual development through the appropriate cognitive and metacognitive mechanisms.
Student Performance Prediction Model Based on Discriminative Feature Selection
Authors: Lu Haixia , Yuan Jinsong
Published: October 2018

It is a hot issue to be widely studied to determine the factors affecting students' performance from the perspective of data mining. In order to find the key factors that significantly affect students' performance from complex data, this paper pro-poses an integrated Optimized Ensemble Feature Selection Algorithm by Density Peaks (DPEFS). This algorithm is applied to the education data collected by two high schools in China, and the selected discriminative features are used to con-struct a student performance prediction model based on support vector machine (SVM). The results of the 10-fold cross-validation experiment show that, com-pared with various feature selection algorithms such as mRMR, Relief, SVM-RFE and AVC, the SVM student performance prediction model based on the fea-ture selection algorithm proposed in this paper has better prediction performance. In addition, some factors and rules affecting student performance can be extracted from the discriminative features selected by the feature selection algorithm in this paper, which provides a methodological and technical reference for teachers, edu-cation management staffs and schools to predict and analyze the students’ per-formances.
The Design and Application of Flip Classroom Teaching Based on Computer Technology
Authors: Li Jia , Zhang Xiaoxia , Hu Zijun
Published: October 2018

The promotion and application of computer technology in the education field has been driving the continuous innovation and development of traditional teaching methods. As a new type of blended learning model, flipping classroom can be well combined with computer technology to effectively improve the quality of education and teaching in colleges and universities. he Moodle provides a good network support platform for the implementation of flipping classroom. This pa-per aims to develop a new flipped classroom teaching model. Supported by Moodle and adhering to the philosophy of self-learning, this teaching model ar-ranges learning tasks according to the different characteristics and needs of learn-ers. Through interactions, it can develop students’ self-learning abilities and im-prove their learning efficiency; through online tracking, it can understand stu-dents’ learning dynamics in time and guide them in preview of knowledge points before class to allow them to think clearly. The purpose of this paper is to study the effects of the flipped classroom teaching method based on Moodle so as to find out what to improve in this model and make it widely applied in college teaching to cultivate more applied talents.
Intelligent System for College English Listening and Writing Training
Authors: Li Cui
Published: October 2018

This paper builds on the requirements of listening and writing, conducts a de-tailed analysis on demands and a feasibility study, and designs a set of intelligent English listening and writing training system. This system carries out an analysis on demands from three main aspects—the orchestration system before the test, the mock test subsystem during the test and the achievement management system after the test, and describes the functions of the college English listening and speaking simulation test system. After technical analysis, the non-functional re-quirements of the system are introduced. The design of the system makes a hier-archical description of the system’s overall architecture, achievement management architecture and sorchestration system architecture, and demonstrates database design, design and interface design of this system. The test demonstrates favora-ble results and this system meet the functional requirements.
The System for Driver Fatigue Monitoring Using Decision Tree via Wireless Sensor Network for Intelligent Transport System
Authors: Yimyam Worawut , Ketcham Mahasak
Published: October 2018

Researchers propose new algorithm to monitor fatigue of driver by tracking the movements of the eyes. This can classify the opening and closing eyes by using Haar-Like Features and Region of Interest techniques. The fatique can be classified by decision tree classification. The system works in real time and sends message to the mobile phone to alert the driver via Line Application. The results showed that the program can detect face and classify opening and closing eyes accurately at 99.93 percent in which it yielded higher accuracy than other algorithms.
A Novel Wireless Sensor Node Positioning Algorithm Based on Ant Colony Optimization Algorithm and Neural Network
Authors: Chen Beichen
Published: October 2018

This paper aims to enhance the positioning accuracy of wireless sensor network (WSN) nodes. For this purpose, a WSN node positioning algorithm was proposed based on artificial bee colony (ABC) algorithm and the neural network (NN). First, the parameters between three anchor nodes and the target node were measured. Then, the ABC and NN were introduced to simulate and predict the ranging error, and the weight was determined according to the results. In the proposed algorithm, the cluster structure was effectively combined with the NN model. The weight of backpropagation NN was optimized by the ant colony optimization (ACO) algorithm. Then, the ACO-optimized NN was used to fuse the data collected by WSN nodes. The simulation results show that the proposed algorithm can improve the positioning accuracy of WSN nodes and reduce the time of the search. The research findings shed new light on the positioning of WSN nodes.
Multi-frame Image Processing Based on Wireless Sensor Networks
Authors: Yang Xianfeng , Jia Xiaojian
Published: October 2018

With multi-frame image processing based on wireless sensor network as research object, this study analyzes the problems existing in the two classic multi-node collaborative distributed image processing algorithms based on wavelet transform using literature analysis, simulation experiment, data analysis and other research methods, proposes a distributed image compression algorithm based on SHIHT with the application of wireless sensor network, SPIHT algorithm and wavelet transform to image compression as theoretical foundations, and adopts the matrix laboratory to simulate the energy performance of the algorithm. Through comparative analysis, the feasibility of distributed image compression algorithm based on SHIHT presented in this study is verified.
RFID Anti-Collision Detection Algorithm Based on Improved Adaptive N-Tree
Authors: Li Yuxia , Zhou Zhinan
Published: October 2018

This paper proposes a type of improved adaptive N-tree anti-collision algorithm based on the traditional one for RFID system by combination with maximum likelihood estimation and probe pre-detection. This algorithm inherits some features from Alpha- and tree-based anti-collision algorithms and effectively restrain the star-vation of the two algorithms. It has also filled in the gaps of tag collision with higher probability. The study turns out that the improved adaptive N-tree anti-collision algorithm as proposed can feature adaptive choice of the value N of the tree, length breaks of free timeslots, restraints on defects such as more tag classification and higher collision probability just as what the traditional tree-based algorithm has. N-tree built by level-to-level frame identification eliminates the free timeslots, and improves the tag identification precision for the RFID system. The results from simulation experiment reveal that the algorithm proposed in this paper has lower Error Sampling Reckon (ESR) and Throughputâ€‚Rate Deviation (TRD), and features large throughput rate (87%), low delay of tag recognition and minimum timeslots, and etc. hence to be better applied in large-scale logistics and other fields where fast information recognition is involved.
Design of Motor Control System Based on Wireless Sensor Network
Authors: Yuan Herong , Song Jingbin
Published: October 2018

More and more modern devices are controlled by miniature special motors. But many existing miniature special motors are using mostly independent test methods through wire communication. In this paper, starting from the requirements of motor testing and the situation of workshop environment, a motor measurement and control system based on wireless sensor network is proposed and designed. This paper elaborates the relevant technical analysis and specific implementation of TT & C module, wireless terminal, wireless router, wireless gateway and host computer measurement and control module. At last, the test function and effect of the system are explained according to the test samples. The reliability and stability of the system are verified through reliability analysis.
La Cour Européenne des Droits de l'Homme procède à une condamnation en demi-teinte de la surveillance “de masse”.
Authors: Foegle Jean-Philippe
Published: October 2018

Particulièrement riche mais également particulièrement décevant, l'arrêt Big Brother Watch pousse à son paroxysme la logique de procéduralisation de la vie privée à l'oeuvre dans le cadre du droit de l'Union Européenne et du droit de la Convention Européenne des Droits de l'Homme. Tout en condamnant un système de surveillance particulièrement intrusif, la Cour Européenne des Droits de l’Homme procède à une légitimation de facto du recours à des systèmes de surveillance digitale « de masse ». De manière similaire, les juges de Strasbourg réaffirment la nécessité d’instaurer un contrôle indépendant des activités de surveillance digitale tout en neutralisant l'exigence d'un contrôle judiciaire préalable de celles-ci
Editorial comments on 2016 volume of HSAG
Authors: Poggenpoel Marie
Published: October 2018

N/a
Reviewer Acknowledgement
Authors: Office Editorial
Published: October 2018

N/a
Verwante en soortgelyke strominge langs die anabaptisme in die sestiende eeu
Authors: Steenkamp J.J.
Published: October 2018

No abstract available.
Die boodskap van Nicea
Authors: Van Zyl F.J.
Published: October 2018

No abstract available.
Malignant mesothelioma of tunica vaginalis without any risk factors
Authors: Punatar Chirag B. , Jadhav Kunal K. , Kumar Vikash , Sagade Sharad N.
Published: October 2018

Malignant mesothelioma (MM) of the tunica vaginalis (TV) is a rare tumor. It is seen in elderly patients, with painless scrotal swelling being the most common presentation. The exact etiology is unknown; a few risk factors have been suggested. Here, we present an uncommon case of MM of TV without any known predisposing factors. We also discuss the possible risk factors, clinical presentation, pathological features and the difficulties in diagnosis, and management of this rare malignancy.
Spectrum of urogenital tumors in males in Sub-Himalayan region
Authors: Panwar Rakesh , Gulati Anchana , Kaushik Rajni , Kaushal Vijay , Raina Pamposh
Published: October 2018

Aims:

The clinical presentation and frequency of urogenital tumors varies in different regions of the world. This study was undertaken to analyze the frequency, clinical presentation, and the histopathological spectrum of the various male urogenital tumors diagnosed over a period of 3 years in a tertiary care institute.

Materials and Methods:

Three-year data were collected from the histopathology laboratory, which included all the cases of male urogenital tumors which were diagnosed histopathologically between November 2012 and October 2015.

Results:

A total of 10,297 surgical specimens of male patients were received in 3 years, of which 1749 were tumors of various organs in males. Of 1749 surgical specimens, 455 were genitourinary tumors. Frequency of urogenital tumors in males was 13.05%. Malignant tumors comprised the majority (99.53%). The age of the patients ranged from 19 to 98 years. The maximum number of patients was in the 5th–7th decade and the mean age of presentation was 64 years. Urinary bladder was the most common site for urogenital tumors (61.09%), with urothelial carcinoma being the most common histological type. Prostatic adenocarcinoma, renal cell carcinoma, and penile squamous cell carcinoma accounted for a significant number of cases. Testicular tumors were the least common and included predominantly mixed germ cell tumors.

Conclusion:

This study can be taken as a small step toward making the registry of patients with urogenital tumors providing valuable information regarding the frequency, clinical presentation, and histological spectrum. Large population-based studies for a longer duration of time across both males and females are needed in the ever-changing trends of urogenital tumors.
Staging a great escape -Incidentally detected renal urothelial carcinoma with extensive squamous metaplasia presenting as pyonephrosis
Authors: Gaur Kavita , Gupta Latika , Saran Ravindra Kumar , Ghuliani Deepak
Published: October 2018

Incidentally, detected upper urinary tract urothelial carcinoma is a rare entity. We report the case of a 70-year-old female patient who presented with flank pain, pyuria, fever, and a unilateral nonfunctioning kidney with nephrolithiasis and pyonephrosis on pyelography. Routine imaging failed to identify a mass lesion. In an Indian setting, the clinical differential of tuberculosis was considered likely. A nephrectomy was performed in view of the poor perfusion and functional status of the right kidney. Histopathological examination of the kidney showed a tumor of urothelial origin arising at the renal pelvis displaying extensive squamous metaplasia. Such a near total metaplastic change is rare and has hitherto been undescribed in the renal pelvis. Activation of pleuripotent urothelial stem cells in the setting of chronic irritation and inflammation may be the pathogenetic process behind such an occurrence.
Quantitative accuracy of positron emission tomography/magnetic resonance and positron emission tomography/computed tomography for cervical cancer
Authors: Oldan Jorge Daniel , Khandani Amir Hossein , Fielding Julia R. , Jones Ellen Louise , Gehrig Paola Alvarez , Sills Tiffany , Roy Pinakpani , Lin Weili
Published: October 2018

With the spread of positron emission tomography/magnetic resonance (PET/MR), the question of comparability of studies becomes important. We aim to determine whether PET/MR and PET/computed tomography (PET/CT) are comparable for the case of cervical cancer. Fifteen cervical cancer patients identified by either a radiation oncologist or an oncologic surgeon had both PET/MR and PET/CT performed for initial staging within 3 weeks. We then compared the results both quantitatively (measuring standardized uptake values [SUVs] on visible lesions) as well as qualitatively (having radiologists and nuclear medicine physicians interprets the results). While interpretations between PET/MR and PET/CT varied in many cases, SUVs of primary lesions were similar to within 25% in all but one case, and correlation coefficient was 0.92. Maximum SUV ranged between 4.9 and 25.2 for PET-MR and between 5.8 and 30.4 for PET-CT for primary tumors and between 1.5 and 18.8 for PET-MR and between 1.8 and 20.8 for PET-CT for nodes. However, clinical reads often varied significantly between PET/MR and PET/CT. This suggests that SUV is similar on PET/MR and PET/CT although the differing anatomic modalities available for correlation may make the difference in terms of qualitative interpretation.
18F-fluorodeoxyglucose positron emission tomography/computed tomography in carcinoma of unknown primary: A subgroup-specific analysis based on clinical presentation
Authors: Thapa Pradeep , Kalshetty Ashwini , Basu Sandip
Published: October 2018

The aim of this study was to explore the clinical efficacy of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in tumor detection in patients with proven or suspected carcinoma of unknown primary origin (CUP) and making a subgroup-specific analysis. This was a retrospective, cross-sectional survey of patients with CUP syndrome who were referred for 18F-FDG PET-CT studies over a 2-year period. FDG-PET-CT scans were performed in compliance with the standard whole-body protocol, i.e., at least 6 h of fasting and were carried out with injected FDG radioactivity dose between 259 MBq and 370 MBq. The time from FDG injection to PET data acquisition was between 60 and 90 min. PET/CT scanning was acquired from the skull base to the upper third of the thighs. Nonenhanced, low-dose attenuation correction CT (110/70 kV/mAs) was performed for all patients. Twenty-one patients of clinically designated with CUP (male:female = 7:14; age range: 42–70 years; mean age: 57.95 years) fulfilling the inclusion criteria were enrolled in this analysis. The patients were subdivided into two groups: A - Those with histopathological proof (n = 12); B - Those with clinical/tumor markers/radiological suspicion of malignancy (n = 9). Among the first group, the sites of metastases in decreasing order of frequency were lymph nodes (n = 9/20; 75%), brain (n = 2; 16.67%), and liver (n = 1; 8.33%). In group B, six patients (66.7%) presented with hypodense/enhancing lesions in the brain and three (33.3%) had altered marrow signal intensity of spine. Overall, hypermetabolic lesions on FDG-PET/CT indicating the primary tumor sites were identified in 14 patients (66.7%). Twelve out of 14 primary sites were subsequently proven by histopathology, whereas two patients with biopsy-proven metastatic lesions in brain, with suspicious primary site in lung had been corroborated by FDG-PET/CT revealing multiple other metastatic sites, were not biopsied and were subsequently enrolled for palliative chemotherapy. When the results were examined individually in each of the Group A and Group B, the primary tumor detection rate was 58.3% and 77.7%, respectively. The identified primary tumor sites were lung 9/14 (64.4%), uterus/cervi 2/14 (14.3%), breast 1/14 (7.1%), esophagus 1/14 (7.1%), and aryepiglottic fold 1/14 (7.1%). In conclusion, FDG-PET/CT is not only helpful in histologically proven cases of CUP (irrespective of the metastatic sites), this modality also demonstrates high tumor detection rate in patients with clinical/radiological suspicion of malignancy. Being a whole body technique, it can additionally aid in disease staging in these patients which could be potentially helpful in their clinical management.
Giant simple biliary cyst infection treated with minimally invasive percutaneous drainage
Authors: Rocha Rafael , Falsarella Priscila , Pereira De Azevedo Andre , Garcia Rodrigo
Published: October 2018

We describe a minimally invasive alternative approach in a patient with infected hepatic cyst to stabilize the patient before definitive surgery. A 58-year-old man presented with fever and hypotension after 2 weeks of asthenia, chills, weight loss, slight abdominal pain, and a previous asymptomatic simple hepatic cyst. On ultrasound, a giant heterogeneous hepatic cyst with thick wall was noted. A positron emission tomography-computed tomography scan was indicated and demonstrated high uptake (standardized uptake value = 7.6) in the wall of the cyst, suggestive of infection. He underwent percutaneous drainage guided by the tomography. A 12 Fr drain was positioned inside the collection and 5 L of purulent material was aspirated from the cyst, and at day 12th, surgical resection was performed. Histopatological analysis confirmed a simple biliary cyst. The patient remains asymptomatic on 1-year follow-up. Percutaneous drainage before surgical treatment allowed the definitive approach to be performed with the patient in better clinical conditions.
Clinical utility of 188Rhenium-hydroxyethylidene-1,1-diphosphonate as a bone pain palliative in multiple malignancies
Authors: Shinto Ajit , Mallia Madhava , Kameswaran Mythili , Kamaleshwaran K , Joseph Jephy , Radhakrishnan E , Upadhyay Indira , Subramaniam R , Sairam Madhu , Banerjee Sharmila , Dash Ashutosh
Published: October 2018

188Rhenium-hydroxyethylidene-1,1-diphosphonate (188Re-HEDP) is a clinically established radiopharmaceutical for bone pain palliation of patients with metastatic bone cancer. Herein, the effectiveness of 188Re-HEDP for the palliation of painful bone metastases was investigated in an uncontrolled initial trial in 48 patients with different types of advanced cancers. A group of 48 patients with painful bone metastases of lung, prostate, breast, renal, and bladder cancer was treated with 2.96–4.44 GBq of 188Re-HEDP. The overall response rate in this group of patients was 89.5%, and their mean visual analog scale score showed a reduction from 9.1 to 5.3 (P < 0.003) after 1 week posttherapy. The patients did not report serious adverse effects either during intravenous administration or within 24 h postadministration of 188Re-HEDP. Flare reaction was observed in 54.2% of patients between day 1 and day 3. There was no correlation between flare reaction and response to therapy (P < 0.05). Although bone marrow suppression was observed in patients receiving higher doses of 188Re-HEDP, it did not result in any significant clinical problems. The present study confirmed the clinical utility and cost-effectiveness of 188Re-HEDP for palliation of painful bone metastases from various types of cancer in developing countries.
False-positive prostate cancer bone metastases on magnetic resonance imaging correctly classified on gallium-68-prostate-specific membrane antigen positron emission tomography computed tomography
Authors: Abubakar Sofiullah , Amoako Yaw , Tag Naima , Kotze Tessa
Published: October 2018

Imaging in prostate cancer is important in defining the local extent of disease, nodal involvement, and identifying metastases. Bone scan is the most commonly used modality for identification of bone metastasis in prostate cancer despite its reported low sensitivity and specificity compared to magnetic resonance imaging (MRI) which is the imaging gold standard for bone metastasis. Gallium-68 prostate-specific membrane antigen positron emission tomography-computed tomography (68Ga PSMA PET-CT) imaging is a relatively new addition to the imaging modalities in prostate cancer. This is a report of a patient with high-risk prostate cancer with features consistent with skeletal metastases on MRI but negative for skeletal metastases on bone scan and 68Ga PSMA PET CT. Histology confirmed the absence of skeletal metastases.
Electromagnetic Compatibility Measurement Procedures and Limits for Components of Vehicles, Boats (up to 15 m), and Machines (Except Aircraft) (16.6 Hz to 18 GHz)
Authors:   Electromagnetic Compatibility (EMC) Standards
Published: October 2018

This SAE Standard covers the measurement of voltage transient immunity and within the applicable frequency ranges, audio (AF) and radio frequency (RF) immunity, and conducted and radiated emissions.

By reference, ISO 11452-3, ISO 11452-7, ISO 11452-8, ISO 11452-10, ISO 11452-11, ISO 11452-2, and the emissions portion of ISO 7637-2 are adopted in place of SAE J1113-24, SAE J1113-3, SAE J1113-22, SAE J1113-2, SAE J1113-28, SAE J1113-21, and SAE J1113-42, respectively. In the event that an amendment is made, or a new edition is published, the new ISO document shall become part of this standard 6 months after the publication of the ISO document. SAE reserves the right to identify exceptions to the published ISO document with the exceptions to be documented in SAE J1113-24, SAE J1113-3, SAE J1113-22, SAE J1113-2, SAE J1113-28, SAE J1113-21, and SAE J1113-42, respectively.

By reference, IEC CISPR 25 is adopted as the standard for the measurement of component emissions. In the event that an amendment is made, or a new edition is published, the new IEC document shall become part of this standard 6 months after the publication of the IEC document. SAE reserves the right to identify exceptions to the published IEC document with the exceptions to be documented in SAE J1113-41.

Emissions from intentional radiators are not controlled by this document. (See applicable appropriate regulatory documents.) The immunity of commercial mains powered equipment to over voltages and line transients is not covered by this document.
MicroRNA-16 inhibits the lipopolysaccharide-induced inflammatory response in nucleus pulposus cells of the intervertebral disc by targeting TAB3
Authors: Du Ketao , He Xuguang , Deng Jiaqin
Published: October 2018

Introduction

A variety of inflammatory mediators are produced by the degenerative human intervertebral disc (IVD) tissues spontaneously, suggesting their role in the development of intervertebral disc degeneration (IDD). Our present study was designed to investigate the regulatory effect of microRNA-16 (miR-16) on the lipopolysaccharide (LPS)-induced inflammatory response in nucleus pulposus (NP) cells of the IVD.

Material and methods

NP cells were treated with LPS to induce inflammatory responses. The expression of miRNA and genes was determined by qRT-PCR. Western blot and an ELISA kit were used to detect the proteins and protein expression, respectively. A dual luciferase reporter assay was applied to identify the correlation between a miRNA and a gene, and to test nuclear factor-B (NF-B) activity.

Results

The results suggested that miR-16 positively regulated the mRNA and protein expression of extracellular matrix (ECM) genes (including aggrecan and collagen II) in NP cells, while it was negatively correlated with ECM degrading enzymes (including MMP3, MMP13, ADAMTS4, ADAMTS5) and related genes of nitric oxide (NO) reaction. Further studies revealed that miR-16 could oppositely regulate NF-B and MAPK pathways by directly mediating their upstream gene TAB3.

Conclusions

Our study suggested that, in NP cells of the IVD, miR-16 could exert inhibitory effects on the LPS-induced inflammatory response through NF-B and MAPK pathways by directly mediating TAB3. In this way, miR-16
would play a protective role against LPS-induced IDD and inflammation. Therefore, miR-16 may be a novel therapeutic target for the inhibit of the ECM in the IVD.
Vaspin (but not neuropeptide B or neuropeptide W) as a possible predictor of body weight normalization in anorexia nervosa
Authors: Grzelak Teresa , Tyszkiewicz-Nwafor Marta , Dutkiewicz Agata , Mikulska Aniceta Ada , Dmitrzak-Weglarz Monika , Slopien Agnieszka , Czyzewska Krystyna , Paszynska Elzbieta
Published: October 2018

Introduction

The aim of the study was to evaluate the correlation between the nutritional status of patients with anorexia nervosa (AN) and levels of vaspin (VASP), neuropeptide B (NPB), neuropeptide W (NPW) and total antioxidant status (TAS).

Material and methods

Ninety serum samples collected from 30 teenage female patients during the acute stage of AN and 30 healthy persons (CONTR) were subjected to biochemical analysis; patients with AN were examined at the beginning of the study (AN-I) and after hospitalization (AN-II), as a result of which partial stabilization of anthropometric measurements was achieved (an increase of body mass index (BMI) by 3.5 kg/m2).

Results

Vaspin levels dropped at the end of the hospitalization (compared to AN-I, p < 0.05), achieving values comparable to the CONTR; moreover there was a positive correlation between VASP level and the achieved body weight in AN-II (p < 0.05). Positive correlations were also noted with regard to VASP vs. NPB in AN-I (p < 0.02) (and AN-II, p < 0.013), as well as in the case of VASP vs. NPW in the same groups (p < 0.02 and p < 0.015, respectively). NPB concentration was higher in AN-I (p < 0.05) and AN-II (p < 0.018) than in CONTR, whereas there were no differences (p > 0.05) with regard to levels of VASP, NPW, or TAS.

Conclusions

The high level of NPB despite treatment and normalization of VASP level may suggest that there are chronic neuroendocrine disorders at play in anorexia nervosa.
Is there a relation between vitamin D, interleukin-17, and bone mineral density in patients with inflammatory bowel disease?
Authors: Krela-Kazmierczak Iwona , Szymczak-Tomczak Aleksandra , Tomczak Maciej , Lykowska-Szuber Liliana , Eder Piotr , Kucharski Marcin A. , Stawczyk-Eder Kamila , Waszak Katarzyna , Karczewski Jacek , Dobrowolska Agnieszka
Published: October 2018

Introduction

In inflammatory bowel diseases (IBD), osteopenia and osteoporosis constitute a significant medical problem. Cytokines, especially IL-17, play an important role in the pathogenesis of IBD and osteoporosis. Vitamin D is a regulator of bone metabolism, and helps maintain immune system homeostasis.

Material and methods

The research sample consisted of 208 persons: 83 patients (age 35 ±11.99 years) with Crohn’s disease (CD); 86 patients (age 39.58 ±14.74 years) with ulcerative colitis (UC); and 39 persons (age 30.74 ±8.63 years) in the control group (CG). Clinical data on bone mineral density of the lumbar spine (L2-L4), bone mineral density of the femoral neck (FN), and body mass index (BMI) were collected. 25OHD and IL-17 serum concentrations were also measured.

Results

Body mass index (kg/m2) results: in CD, 21.51 ±3.68; in UC, 23.31 ±4.38; and in CG, 24.57 ±3.45 (p < 0.01). Densitometry results for L2–L4 T-score SD: in CD –0.83 ±1.45; in UC –0.47 ±1.15; in CG 0.09 ±0.70. Densitometry results for FN T-score SD: in CD –0.62 ±1.26; in UC –0.29±1.17; in CG 0.41 ±1.03 25OHD (ng/ml) serum concentrations: in CD, 21.33±12.50; in UC, 22.04±9.56; in CG, 21.56±9.11 (ns). IL-17 (pg/ml) serum concentrations: in CD, 8.55±10.99; in UC, 11.67±12.97; in CG, 5.16±9.11 (ns).

Conclusions

Inflammatory bowel diseases patients and persons from the CG did not differ in vitamin D or IL-17 levels. Patients with a mild course of the disease had a higher vitamin D concentration and bone mineral density. In UC, higher vitamin D concentrations were associated with lower IL-17 concentrations. The IBD patients with a severe course of the disease had a lower body mass than those in the CG and the patients with a mild course of the disease.
The impact of measures to reduce road dust, evaluated for a street
canyon in Helsinki
Authors: Stojiljkovic Ana , Kauhaniemi Mari , Kukkonen Jaakko , Kupiainen Kaarle , Karppinen Ari , Denby Bruce Rolstad , Kousa Anu , Niemi Jarkko V. , Ketzel Matthias
Published: October 2018

Abstract. We have evaluated numerically how effective a few selected measures would be for reducing road dust. The selected measures included the reduction of the use of studded tyres in light-duty vehicles and phasing-out of salt or sand in traction control. We have evaluated these measures for a street canyon location in central Helsinki, for four years (2007–2009 and 2014). Air quality measurements were conducted in the street canyon for two years, 2009 and 2014. Two road dust emission models, NORTRIP and FORE, were applied in combination with the street canyon dispersion model OSPM to compute the street increments of PM10 within the street canyon. The predicted concentrations were compared with the air quality measurements. Both models reproduced the seasonal variability of the PM10 concentrations but under-predicted the yearly mean values. It was found that the largest reductions of concentrations could potentially be achieved by reducing the fraction of vehicles that use studded tyres. For instance, a 30 % percent decrease in the number of vehicles using studded tyres would result in an average decrease of the non-exhaust increment of PM10 from 10 to 22 %, depending on the model used and the year considered. The corresponding decrease after removal of sanding and salting would be from 4 % and 20 % and from 0.1 % to 4 %, respectively. The results can be used for finding optimal strategies for reducing the high springtime particulate matter concentrations originated from road dust.
Particulate organic matter controls benthic microbial N retention and
N removal in contrasting estuaries of the Baltic Sea
Authors: Bartl Ines , Hellemann Dana , Rabouille Christophe , Schulz Kirstin , Tallberg Petra , Hietanen Susanna , Voss Maren
Published: October 2018

Abstract. Estuaries worldwide are known to act as filters of land-derived N loads, yet their variable environmental settings can affect microbial nitrogen (N) retention and removal and thus the coastal filter function. We investigated microbial N-retention (nitrification, ammonium assimilation) and N-removal (denitrification, anammox) in the aphotic benthic systems (here defined as: bottom boundary layer [BBL] and sediment) of two Baltic Sea estuaries that differ in riverine N loads, trophic state, bottom topography, and sediment type. Contrary to our expectations, nitrification rates (5–227 nmol L−1 d−1) in the BBL neither differed between the eutrophied Vistula estuary and the oligotrophic Öre estuary, nor between seasons. Ammonium assimilation rates were slightly higher in the oligotrophic Öre estuary in spring but did not differ between estuaries in summer (9–704 nmol L−1 d−1). In the sediment, no anammox was found in either estuary and denitrification rates were higher in the eutrophied (349 ± 117 µmol N m−2 d−1) than in the oligotrophic estuary (138 ± 47 µmol N m−2 d−1). Irrespective of their differences, in both estuaries the quality of the mainly phytoplankton-derived particulate organic matter (POM) – evaluated by means of C : N and POC : Chl.a ratios – seemed to control N-cycling processes through the availability of particulate organic N and C as substrate sources. Our data suggest, that in stratified estuaries, phytoplankton-derived POM is an essential link between riverine N loads and benthic N cycling and may function as a temporary N reservoir via long particle residence time or coastal parallel transport. Even at low process rates, effective coastal filtering would thus be achieved by the increased time available for the recycling of N via microbial retention processes until its permanent removal via denitrification.
HOMMEXX 1.0: A Performance Portable Atmospheric Dynamical Core for the Energy Exascale Earth System Model
Authors: Bertagna Luca , Deakin Michael , Guba Oksana , Sunderland Daniel , Bradley Andrew M. , Tezaur Irina K. , Taylor Mark A. , Salinger Andrew G.
Published: October 2018

Abstract. We present an architecture-portable and performant implementation of the atmospheric dynamical core (HOMME) of the Energy Exascale Earth System Model (E3SM). The original Fortran implementation is highly performant and scalable on conventional architectures using MPI and OpenMP. We rewrite the model in C++ and use the Kokkos library to express on-node parallelism in a largely architecture-independent implementation. Kokkos provides an abstraction of a compute node or device, layout-polymorphic multidimensional arrays, and parallel execution constructs. The new implementation achieves the same or better performance on conventional multicore computers and is portable to GPUs. We present performance data for the original and new implementations on multiple platforms, on up to 5400 compute nodes, and study several aspects of the single- and multi-node performance characteristics of the new implementation on conventional CPU, Intel Xeon Phi Knights Landing, and Nvidia V100 GPU.