bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figures 1 - 10, Tables 1 - 4 from Selective and Potent Akt Inhibition Triggers Anti-Myeloma Activities and Enhances Fatal Endoplasmic Reticulum Stress Induced by Proteasome Inhibition
Authors: Mimura Naoya , Hideshima Teru , Shimomura Toshiyasu , Suzuki Rikio , Ohguchi Hiroto , Rizq Ola , Kikuchi Shohei , Yoshida Yasuhiro , Cottini Francesca , Jakubikova Jana , Cirstea Diana , Gorgun Gullu , Minami Jiro , Tai Yu-Tzu , Richardson Paul G. , Utsugi Teruhiro , Iwama Atsushi , Anderson Kenneth C.
Published: March 2023

PDF file - 648K, Figure S1. TAS-117 is a novel potent and selective inhibitor of Akt kinases. Figure S2. Basal expression of phosphorylated Akt and Akt in MM cell lines. Figure S3. TAS-117 inhibits neither MEK/ERK nor JAK2/STAT pathway. Figure S4. TAS-117 modulates phenotype of side population (SP) cells and induces cytotoxicity in SP cells associated with Akt inhibition. Figure S5. TAS-117 overcomes cytoprotective effects conferred by cytokines by blocking Akt activation. Figure S6. TAS-117 treatment does not affect viability in BMSCs. Figure S7. TAS-117 triggers cleavage of caspase and PARP in MM cells. Figure S8. TAS-117 induces autophagosome formation in MM cells. Figure S9. TAS-117 in combination with bortezomib does not affect body weight of mice. Figure S10. TAS-117 in combination with carfilzomib induces synergistic cytotoxicity in RPMI8226 cells with low baseline of p-Akt, associated with inhibition of carfilzomib-induced p-Akt. Table S1. TAS-117 combination indices (CI) with bortezomib in MM.1S cells. Table S2. TAS-117 combination indices (CI) with bortezomib in RPMI8226 cells. Table S3. TAS-117 combination indices (CI) with carfilzomib in MM.1S cells. Table S4. TAS-117 combination indices (CI) with carfilzomib in RPMI8226 cells.
Supplementary Figure Legends from Selective and Potent Akt Inhibition Triggers Anti-Myeloma Activities and Enhances Fatal Endoplasmic Reticulum Stress Induced by Proteasome Inhibition
Authors: Mimura Naoya , Hideshima Teru , Shimomura Toshiyasu , Suzuki Rikio , Ohguchi Hiroto , Rizq Ola , Kikuchi Shohei , Yoshida Yasuhiro , Cottini Francesca , Jakubikova Jana , Cirstea Diana , Gorgun Gullu , Minami Jiro , Tai Yu-Tzu , Richardson Paul G. , Utsugi Teruhiro , Iwama Atsushi , Anderson Kenneth C.
Published: March 2023

PDF file - 160K
Supplementary Table 2 from EWS–WT1 Oncoprotein Activates Neuronal Reprogramming Factor ASCL1 and Promotes Neural Differentiation
Authors: Kang Hong-Jun , Park Jun Hong , Chen WeiPing , Kang Soo Im , Moroz Krzysztof , Ladanyi Marc , Lee Sean Bong
Published: March 2023

XLSX file - 77K, GO analysis of primary DSRCT-induced genes compared to other tumor types.
Supplementary Table 1 from EWS–WT1 Oncoprotein Activates Neuronal Reprogramming Factor ASCL1 and Promotes Neural Differentiation
Authors: Kang Hong-Jun , Park Jun Hong , Chen WeiPing , Kang Soo Im , Moroz Krzysztof , Ladanyi Marc , Lee Sean Bong
Published: March 2023

XLSX file - 378K, GO analysis of E-KTS and E+KTS induced genes in MEFs.
Supplementary Tables S1-S5 from Network Modeling of TGFβ Signaling in Hepatocellular Carcinoma Epithelial-to-Mesenchymal Transition Reveals Joint Sonic Hedgehog and Wnt Pathway Activation
Authors: Steinway Steven Nathaniel , Zañudo Jorge G.T. , Ding Wei , Rountree Carl Bart , Feith David J. , Loughran Thomas P. , Albert Reka
Published: March 2023

The full names of components in the EMT network corresponding to the abbreviated node labels used in Figure 3 and Figure 5A (S1); Evidence for interactions among nodes in the EMT network (S2); Boolean update rules and initial state of the 68 node EMT network (S3); Key experimental outcomes reproduced by the EMT network model (S4); Boolean rules and initial state for the 19 node reduced EMT network (S5).
Supplementary Figures 1 - 5, Methods from Globo-H Ceramide Shed from Cancer Cells Triggers Translin-Associated Factor X-Dependent Angiogenesis
Authors: Cheng Jing-Yan , Wang Sheng-Hung , Lin Juway , Tsai Yi-Chien , Yu John , Wu Jen-Chine , Hung Jung-Tung , Lin Jin-Jin , Wu Yih-Yiing , Yeh Kun-Tu , Yu Alice L.
Published: March 2023

Supplementary Figure S1. Globo-H expression on breast cancer cells and shedding of GHCer from MDA-MB-157 cells into MVs. Supplementary Figure S2. Structure of TRAX, PLCβ1 and Globo-H. Supplementary Figure S3. Prediction of secondary structure of PLCβ1. Supplementary Figure S4. Amino-acid sequence alignment of PLCβ1 and PLCβ3. Supplementary Figure S5. Prediction of TRAX-PLCβ1 binding complexes.
Data Supplement from Combined SFK/mTOR Inhibition Prevents Rapamycin-Induced Feedback Activation of AKT and Elicits Efficient Tumor Regression
Authors: Yori Jennifer L. , Lozada Kristen L. , Seachrist Darcie D. , Mosley Jonathan D. , Abdul-Karim Fadi W. , Booth Christine N. , Flask Chris A. , Keri Ruth A.
Published: March 2023

Supplementary Figure S2. Rapamycin induction of p-AKT occurs within 1 hour and is not due to increased levels of p-Src.
Data Supplement from Combined SFK/mTOR Inhibition Prevents Rapamycin-Induced Feedback Activation of AKT and Elicits Efficient Tumor Regression
Authors: Yori Jennifer L. , Lozada Kristen L. , Seachrist Darcie D. , Mosley Jonathan D. , Abdul-Karim Fadi W. , Booth Christine N. , Flask Chris A. , Keri Ruth A.
Published: March 2023

Supplementary Figure S4. Combination dasatinib and rapamycin does not increase apoptosis over single agent treatment.
Supplemental Figure 2 from Force Engages Vinculin and Promotes Tumor Progression by Enhancing PI3K Activation of Phosphatidylinositol (3,4,5)-Triphosphate
Authors: Rubashkin Matthew G. , Cassereau Luke , Bainer Russell , DuFort Christopher C. , Yui Yoshihiro , Ou Guanqing , Paszek Matthew J. , Davidson Michael W. , Chen Yunn-Yi , Weaver Valerie M.
Published: March 2023

MECs remodel 3D collagen gels for cell invasion. Individual collagen fibers are stiff and >500nm in diameter.
Supplementary information from Nuclear Factor of Activated T-cell Activity Is Associated with Metastatic Capacity in Colon Cancer
Authors: Tripathi Manish K. , Deane Natasha G. , Zhu Jing , An Hanbing , Mima Shinji , Wang Xiaojing , Padmanabhan Sekhar , Shi Zhiao , Prodduturi Naresh , Ciombor Kristen K. , Chen Xi , Washington M. Kay , Zhang Bing , Beauchamp R. Daniel
Published: March 2023

Supplementary information. Supplementary methods and additional results as referred to in the manuscript
Supplementary File 5 from Nuclear Factor of Activated T-cell Activity Is Associated with Metastatic Capacity in Colon Cancer
Authors: Tripathi Manish K. , Deane Natasha G. , Zhu Jing , An Hanbing , Mima Shinji , Wang Xiaojing , Padmanabhan Sekhar , Shi Zhiao , Prodduturi Naresh , Ciombor Kristen K. , Chen Xi , Washington M. Kay , Zhang Bing , Beauchamp R. Daniel
Published: March 2023

Supplementary File 5. Promoter regions from MURINE NFATc1 target genes showing the locations of NFAT consensus binding sequences and PCR primers.
Supplementary Figures 1-9 from Nuclear Factor of Activated T-cell Activity Is Associated with Metastatic Capacity in Colon Cancer
Authors: Tripathi Manish K. , Deane Natasha G. , Zhu Jing , An Hanbing , Mima Shinji , Wang Xiaojing , Padmanabhan Sekhar , Shi Zhiao , Prodduturi Naresh , Ciombor Kristen K. , Chen Xi , Washington M. Kay , Zhang Bing , Beauchamp R. Daniel
Published: March 2023

Supplementary Figures 1-9. All supplementary data for publication as referenced in the manuscript
Supp Table S4 from In Vivo Disruption of an Rb–E2F–Ezh2 Signaling Loop Causes Bladder Cancer
Authors: Santos Mirentxu , Martínez-Fernández Mónica , Dueñas Marta , García-Escudero Ramón , Alfaya Begoña , Villacampa Felipe , Saiz-Ladera Cristina , Costa Clotilde , Oteo Marta , Duarte José , Martínez Victor , Gómez-Rodriguez Ma José , Martín Ma Luisa , Fernández Manoli , Viatour Patrick , Morcillo Miguel A. , Sage Julien , Castellano Daniel , Rodriguez-Peralto Jose L. , de la Rosa Federico , Paramio Jesús M
Published: March 2023

Supp Table S4. Gene Ontology of Biological processes of the upregulated genes in mouse bladder tumors.
Supplementary Materials and Methods from Host Deficiency in Caveolin-2 Inhibits Lung Carcinoma Tumor Growth by Impairing Tumor Angiogenesis
Authors: Liu Yajun , Jang Sungchan , Xie Leike , Sowa Grzegorz
Published: March 2023

Supplementary Materials and Methods. Generation of Cav-2 KO mice RNA isolation and analysis of specific gene expression by quantitative real time PCR References
Supp Table S12 from In Vivo Disruption of an Rb–E2F–Ezh2 Signaling Loop Causes Bladder Cancer
Authors: Santos Mirentxu , Martínez-Fernández Mónica , Dueñas Marta , García-Escudero Ramón , Alfaya Begoña , Villacampa Felipe , Saiz-Ladera Cristina , Costa Clotilde , Oteo Marta , Duarte José , Martínez Victor , Gómez-Rodriguez Ma José , Martín Ma Luisa , Fernández Manoli , Viatour Patrick , Morcillo Miguel A. , Sage Julien , Castellano Daniel , Rodriguez-Peralto Jose L. , de la Rosa Federico , Paramio Jesús M
Published: March 2023

Supp Table S12. Gene Ontology of Biological processes of the upregulated genes in human recurrent bladder tumors
Supp Table S11 from In Vivo Disruption of an Rb–E2F–Ezh2 Signaling Loop Causes Bladder Cancer
Authors: Santos Mirentxu , Martínez-Fernández Mónica , Dueñas Marta , García-Escudero Ramón , Alfaya Begoña , Villacampa Felipe , Saiz-Ladera Cristina , Costa Clotilde , Oteo Marta , Duarte José , Martínez Victor , Gómez-Rodriguez Ma José , Martín Ma Luisa , Fernández Manoli , Viatour Patrick , Morcillo Miguel A. , Sage Julien , Castellano Daniel , Rodriguez-Peralto Jose L. , de la Rosa Federico , Paramio Jesús M
Published: March 2023

Supp Table S11. Gene Ontology of Biological processes of the downregulated genes in human recurrent bladder tumors.
Supplemental Table 1 and 2 from ERK Mutations Confer Resistance to Mitogen-Activated Protein Kinase Pathway Inhibitors
Authors: Goetz Eva M. , Ghandi Mahmoud , Treacy Daniel J. , Wagle Nikhil , Garraway Levi A.
Published: March 2023

Supplemental Table 1 and 2. Amino acid substitutions for each significantly mutated ERK1/2 nucleotide for the ERK inhibitor screen (Table 1) or the RAF/MEK inhibitor screen (Table 2) and the accompanying resistance phenotype.
Supplemental Figure 5 from Adenosine A2A Receptors Intrinsically Regulate CD8+ T Cells in the Tumor Microenvironment
Authors: Cekic Caglar , Linden Joel
Published: March 2023

Supplementary Figure 5. Effect of A2AR signaling on T cell survival and effector differentiation in B16F10 tumors.
Supplementary Figures 1 - 8 from NQO1 Suppresses NF-κB–p300 Interaction to Regulate Inflammatory Mediators Associated with Prostate Tumorigenesis
Authors: Thapa Dinesh , Meng Peng , Bedolla Roble G. , Reddick Robert L. , Kumar Addanki P. , Ghosh Rita
Published: March 2023

(S1) Basal NQO1 levels in different cancer cells, (S2) Transduction efficiency of NQO1 KD, (S3 and S4) Effects of KD on cellular redox state and AR signaling, (S5) heat maps of differential gene expression with NQO1 KD, (S6) inhibition of NQO1 activity on NFkB-p65 signaling, (S7) Quantification of increased nuclear IKKa following NQO1 KD and (S8) Basal IL-8 message in prostate cancer cells.
Supplementary Table 2 from No Causal Association Identified for Human Papillomavirus Infections in Lung Cancer
Authors: Anantharaman Devasena , Gheit Tarik , Waterboer Tim , Halec Gordana , Carreira Christine , Abedi-Ardekani Behnoush , McKay-Chopin Sandrine , Zaridze David , Mukeria Anush , Szeszenia-Dabrowska Neonila , Lissowska Jolanta , Mates Dana , Janout Vladimir , Foretova Lenka , Bencko Vladimir , Rudnai Peter , Fabianova Eleonora , Tjønneland Anne , Travis Ruth C. , Boeing Heiner , Quirós J. Ramón , Johansson Mikael , Krogh Vittorio , Bueno-de-Mesquita H. Bas , Kotanidou Anastasia , Clavel-Chapelon Françoise , Weiderpass Elisabete , Johansson Mattias , Pawlita Michael , Scelo Ghislaine , Tommasino Massimo , Brennan Paul
Published: March 2023

PDF file - 67KB, Antibodies to type-specific HPV proteins and the risk of lung cancer.
Supplementary Table S1 from GPx2 Suppression of H2O2 Stress Links the Formation of Differentiated Tumor Mass to Metastatic Capacity in Colorectal Cancer
Authors: Emmink Benjamin L. , Laoukili Jamila , Kipp Anna P. , Koster Jan , Govaert Klaas M. , Fatrai Szabolcs , Verheem Andre , Steller Ernst J.A. , Brigelius-Flohé Regina , Jimenez Connie R. , Borel Rinkes Inne H.M. , Kranenburg Onno
Published: March 2023

Supplementary Table S1. The H2O2 stress response metagene.
Supplementary Table Legends from GPx2 Suppression of H2O2 Stress Links the Formation of Differentiated Tumor Mass to Metastatic Capacity in Colorectal Cancer
Authors: Emmink Benjamin L. , Laoukili Jamila , Kipp Anna P. , Koster Jan , Govaert Klaas M. , Fatrai Szabolcs , Verheem Andre , Steller Ernst J.A. , Brigelius-Flohé Regina , Jimenez Connie R. , Borel Rinkes Inne H.M. , Kranenburg Onno
Published: March 2023

Supplementary Table Legends. Legends for Supplementary Tables S1-S5.
Supplementary Figure 2 from Myeloid Expression of Adenosine A2A Receptor Suppresses T and NK Cell Responses in the Solid Tumor Microenvironment
Authors: Cekic Caglar , Day Yuan-Ji , Sag Duygu , Linden Joel
Published: March 2023

Supplementary Figure 2. Myeloid deletion of Adora2a increases lung infiltration of NK cells and antigen specific T cells in mice with melanoma.
Data Supplement from HSV-sr39TK Positron Emission Tomography and Suicide Gene Elimination of Human Hematopoietic Stem Cells and Their Progeny in Humanized Mice
Authors: Gschweng Eric H. , McCracken Melissa N. , Kaufman Michael L. , Ho Michelle , Hollis Roger P. , Wang Xiaoyan , Saini Navdeep , Koya Richard C. , Chodon Thinle , Ribas Antoni , Witte Owen N. , Kohn Donald B.
Published: March 2023

Supplementary Video 1. This is a 3D reconstruction of a 250uCi 18F-FHBG PET/CT scan of an ESO/TK mouse 3h after conscious uptake. Notable areas of uptake are the long bones of the arms and legs, sternum, spine, and thymus.
Supplementary Figure 3 from Targeting the MYC and PI3K Pathways Eliminates Leukemia-Initiating Cells in T-cell Acute Lymphoblastic Leukemia
Authors: Schubbert Suzanne , Cardenas Anjelica , Chen Harrison , Garcia Consuelo , Guo Wei , Bradner James , Wu Hong
Published: March 2023

Cellular and biochemical effects of JQ1 in T-ALL.
Supplementary Figures S1-S11 from Combined Genome and Transcriptome Analysis of Single Disseminated Cancer Cells from Bone Marrow of Prostate Cancer Patients Reveals Unexpected Transcriptomes
Authors: Gužvić Miodrag , Braun Bernhard , Ganzer Roman , Burger Maximilian , Nerlich Michael , Winkler Sebastian , Werner-Klein Melanie , Czyż Zbigniew T. , Polzer Bernhard , Klein Christoph A.
Published: March 2023

Supplementary Figures S1-S11. Supplementary Figure S1 - Workflow employed in this study. Supplementary Figure S2 - Photographs of cell lines stained with isotype antibodies. Supplementary Figure S3 - Box-plot representing BM cell numbers before and after immunomagnetic selection, number of screened cells and number of isolated EpCAM+ cells. Supplementary Figure S4 - Photographs of cell lines stained for EpCAM. Supplementary Figure S5 - Photographs and flowcytometric analysis of BM of control patient spiked with DU145 cells. Supplementary Figure S6 - Expression analysis of BM cell pools. Supplementary Figure S7 - QC of WTA and overview of epithelial transcript expression. Supplementary Figure S8 - Results of expression profiling of all samples. Supplementary Figure S9 - Analysis of WTA controls for HBA2 transcript. Supplementary Figure S10 - CGH profiles of analysed single cells. Supplementary Figure S11 - Establishing conditions for specific amplification of selected fragments by PCR and confirmation of identity of amplified fragments.
Supplementary Movie 2B from mTOR Signaling Feedback Modulates Mammary Epithelial Differentiation and Restrains Invasion Downstream of PTEN Loss
Authors: Ghosh Susmita , Varela Lidenys , Sood Akshay , Park Ben Ho , Lotan Tamara L.
Published: March 2023

MOV - 1224 KB, Acinar morphogenesis in PTEN-/- MCF10A cells treated with vehicle reveals rare, transient invasive protrusions into ECM. 54-hour time-lapse DIC imaging (roughly days 1-3 after plating) of PTEN-/- MCF10A clone #1 treated with vehicle. Invasive cytoplasmic protrusions into surrounding collagen-Matrigel ECM are transient and seen to emerge and retract over time.
Legends for Supplementary Figures S1-S11 from Combined Genome and Transcriptome Analysis of Single Disseminated Cancer Cells from Bone Marrow of Prostate Cancer Patients Reveals Unexpected Transcriptomes
Authors: Gužvić Miodrag , Braun Bernhard , Ganzer Roman , Burger Maximilian , Nerlich Michael , Winkler Sebastian , Werner-Klein Melanie , Czyż Zbigniew T. , Polzer Bernhard , Klein Christoph A.
Published: March 2023

Legends for Supplementary Figures S1-S11. Supplementary Figure S1 - Workflow employed in this study. Supplementary Figure S2 - Photographs of cell lines stained with isotype antibodies. Supplementary Figure S3 - Box-plot representing BM cell numbers before and after immunomagnetic selection, number of screened cells and number of isolated EpCAM+ cells. Supplementary Figure S4 - Photographs of cell lines stained for EpCAM. Supplementary Figure S5 - Photographs and flowcytometric analysis of BM of control patient spiked with DU145 cells. Supplementary Figure S6 - Expression analysis of BM cell pools. Supplementary Figure S7 - QC of WTA and overview of epithelial transcript expression. Supplementary Figure S8 - Results of expression profiling of all samples. Supplementary Figure S9 - Analysis of WTA controls for HBA2 transcript. Supplementary Figure S10 - CGH profiles of analysed single cells. Supplementary Figure S11 - Establishing conditions for specific amplification of selected fragments by PCR and confirmation of identity of amplified fragments.
Supplementary Materials and Methods, Figure Legend, Table S1, Figures S1-S4 from Synergy between the NAMPT Inhibitor GMX1777(8) and Pemetrexed in Non–Small Cell Lung Cancer Cells Is Mediated by PARP Activation and Enhanced NAD Consumption
Authors: Chan Manuel , Gravel Michel , Bramoullé Alexandre , Bridon Gaëlle , Avizonis Daina , Shore Gordon C. , Roulston Anne
Published: March 2023

Supplementary Materials and Methods Supplemenary Figure legends
Supplement Figures from Vitamin D Suppresses Leptin Stimulation of Cancer Growth through microRNA
Authors: Kasiappan Ravi , Sun Yuefeng , Lungchukiet Panida , Quarni Waise , Zhang Xiaohong , Bai Wenlong
Published: March 2023

Supplement Figures. FIGURE s1. EB1089 suppresses HFD-induced ovarian tumor growth in vivo through miR-498. FIGURE s2. EB1089 suppresses HFD-induced increase in ovarian tumor proliferation index through miR-498. FIGURE s3. EB1089 suppresses HFD-induced ovarian tumor growth in mice by inducing apoptosis through miR-498. FIGURE s4. EB1089 does not induce hypercalcemia in mice. FIGURE s5. 1,25(OH)2D3 induces apoptosis at physiological concentrations in a dosage-dependent manner.
Data Supplement from Uncontrolled Inflammation Induced by AEG-1 Promotes Gastric Cancer and Poor Prognosis
Authors: Li Guanghua , Wang Zhao , Ye Jinning , Zhang Xinhua , Wu Hui , Peng Jianjun , Song Wu , Chen Chuangqi , Cai Shirong , He Yulong , Xu Jianbo
Published: March 2023

Supplemental Table 1. Primers used in Quantitative real-time RT-PCR.
Supplementary Figure from JAK-STAT Blockade Inhibits Tumor Initiation and Clonogenic Recovery of Prostate Cancer Stem-like Cells
Authors: Kroon Paula , Berry Paul A. , Stower Michael J. , Rodrigues Greta , Mann Vincent M. , Simms Matthew , Bhasin Deepak , Chettiar Somsundaram , Li Chenglong , Li Pui-Kai , Maitland Norman J. , Collins Anne T.
Published: March 2023

PDF file, 7896K, A. Histology of mouse xenograft. H&E stain of a mouse xenograft derived from a patient with castrate-resistant prostate cancer. Small glandular structures are apparent with large, prominent nucleoli within sheets of undifferentiated tumour cells, indicative of a high grade tumour. x60 magnification. B, C. Dot plots of CD44, CD24 , CD44 and AR expression.
Data Supplement from miR-21 Induces Myofibroblast Differentiation and Promotes the Malignant Progression of Breast Phyllodes Tumors
Authors: Gong Chang , Nie Yan , Qu Shaohua , Liao Jian-You , Cui Xiuying , Yao Herui , Zeng Yunjie , Su Fengxi , Song Erwei , Liu Qiang
Published: March 2023

Supplementary Figure S1. Myofibroblast differentiation is associated with malignant progression of PTs
Data Supplement from miR-21 Induces Myofibroblast Differentiation and Promotes the Malignant Progression of Breast Phyllodes Tumors
Authors: Gong Chang , Nie Yan , Qu Shaohua , Liao Jian-You , Cui Xiuying , Yao Herui , Zeng Yunjie , Su Fengxi , Song Erwei , Liu Qiang
Published: March 2023

Supplementary Figure S2. miR-21 is up-regulated in malignant PTs and correlated with poor prognosis.
Supplemental Materials from Pancreatic Cancer–Specific Cell Death Induced In Vivo by Cytoplasmic-Delivered Polyinosine–Polycytidylic Acid
Authors: Bhoopathi Praveen , Quinn Bridget A. , Gui Qin , Shen Xue-Ning , Grossman Steven R. , Das Swadesh K. , Sarkar Devanand , Fisher Paul B. , Emdad Luni
Published: March 2023

Supplemental Materials. Supplemental methods and figure legend
Data Supplement from miR-21 Induces Myofibroblast Differentiation and Promotes the Malignant Progression of Breast Phyllodes Tumors
Authors: Gong Chang , Nie Yan , Qu Shaohua , Liao Jian-You , Cui Xiuying , Yao Herui , Zeng Yunjie , Su Fengxi , Song Erwei , Liu Qiang
Published: March 2023

Supplementary Figure S4. miR-21 targets 3' UTR of smad7 and PTEN.
Data Supplement from miR-21 Induces Myofibroblast Differentiation and Promotes the Malignant Progression of Breast Phyllodes Tumors
Authors: Gong Chang , Nie Yan , Qu Shaohua , Liao Jian-You , Cui Xiuying , Yao Herui , Zeng Yunjie , Su Fengxi , Song Erwei , Liu Qiang
Published: March 2023

Description of additional methods and procedures used in the study.
Supplemental Fig. 4 from Pancreatic Cancer–Specific Cell Death Induced In Vivo by Cytoplasmic-Delivered Polyinosine–Polycytidylic Acid
Authors: Bhoopathi Praveen , Quinn Bridget A. , Gui Qin , Shen Xue-Ning , Grossman Steven R. , Das Swadesh K. , Sarkar Devanand , Fisher Paul B. , Emdad Luni
Published: March 2023

Supplemental Fig. 4. Inhibition of XIAP degradation does not rescue pancreatic cancer cells from [pIC]PEI-induced apoptosis
Supplemental Figure Legends from Oncogene Pathway Activation in Mammary Tumors Dictates FDG-PET Uptake
Authors: Alvarez James V. , Belka George K. , Pan Tien-Chi , Chen Chien-Chung , Blankemeyer Eric , Alavi Abass , Karp Joel S. , Chodosh Lewis A.
Published: March 2023

Supplemental Figure Legends. Legends for Supplemental Figures S1-S2.
Supplementary Table 1 from MicroRNA100 Inhibits Self-Renewal of Breast Cancer Stem–like Cells and Breast Tumor Development
Authors: Deng Lu , Shang Li , Bai Shoumin , Chen Ji , He Xueyan , Martin-Trevino Rachel , Chen Shanshan , Li Xiao-yan , Meng Xiaojie , Yu Bin , Wang Xiaolin , Liu Yajing , McDermott Sean P. , Ariazi Alexa E. , Ginestier Christophe , Ibarra Ingrid , Ke Jia , Luther Tahra , Clouthier Shawn G. , Xu Liang , Shan Ge , Song Erwei , Yao Herui , Hannon Gregory J. , Weiss Stephen J. , Wicha Max S. , Liu Suling
Published: March 2023

Subtypes of the 94 patients.
Supplementary Table S2 from Tenascin-C Protects Cancer Stem–like Cells from Immune Surveillance by Arresting T-cell Activation
Authors: Jachetti Elena , Caputo Sara , Mazzoleni Stefania , Brambillasca Chiara Svetlana , Parigi Sara Martina , Grioni Matteo , Piras Ignazio Stefano , Restuccia Umberto , Calcinotto Arianna , Freschi Massimo , Bachi Angela , Galli Rossella , Bellone Matteo
Published: March 2023

Supplementary Table S2. Kegg enrichment of proteins upregulated in T cells cultured in the presence of TPIN-SCs.
Supplementary Figures S1-S6 from Tenascin-C Protects Cancer Stem–like Cells from Immune Surveillance by Arresting T-cell Activation
Authors: Jachetti Elena , Caputo Sara , Mazzoleni Stefania , Brambillasca Chiara Svetlana , Parigi Sara Martina , Grioni Matteo , Piras Ignazio Stefano , Restuccia Umberto , Calcinotto Arianna , Freschi Massimo , Bachi Angela , Galli Rossella , Bellone Matteo
Published: March 2023

Supplementary Figures S1-S6. Representative dot plots of in vitro inhibition of T cell activation by TPIN-SCs (S1); Non-irradiated TPIN-SCs arrest in vitro T cell activation (S2); TPIN-SCs inhibit restimulation of antigen-experienced T cells but do not affect fully activated T cells (S3); TPIN-SC-conditioned T cells are hyporesponsive (S4); Silencing of TNC modulates the inhibitory activity of TPIN-SCs (S5); CSCs migration is mediated by the CXCR4/CXCL12 axis (S6).
Supplementary Figure S1 from Foretinib Is Effective Therapy for Metastatic Sonic Hedgehog Medulloblastoma
Authors: Faria Claudia C. , Golbourn Brian J. , Dubuc Adrian M. , Remke Marc , Diaz Roberto J. , Agnihotri Sameer , Luck Amanda , Sabha Nesrin , Olsen Samantha , Wu Xiaochong , Garzia Livia , Ramaswamy Vijay , Mack Stephen C. , Wang Xin , Leadley Michael , Reynaud Denis , Ermini Leonardo , Post Martin , Northcott Paul A. , Pfister Stefan M. , Croul Sidney E. , Kool Marcel , Korshunov Andrey , Smith Christian A. , Taylor Michael D. , Rutka James T.
Published: March 2023

Supplementary Figure S1. Subgroup-specific copy number aberrations in primary medulloblastomas
supplementary tables 1-4 from Microenvironmental Remodeling as a Parameter and Prognostic Factor of Heterogeneous Leukemogenesis in Acute Myelogenous Leukemia
Authors: Kim Jin-A , Shim Jae-Seung , Lee Ga-Young , Yim Hyeon Woo , Kim Tae-Min , Kim Myungshin , Leem Sun-Hee , Lee Jong-Wook , Min Chang-Ki , Oh Il-Hoan
Published: March 2023

supplementary tables 1-4. Supplementary Table S1 summarizes the list of antibodies used for flowcytometry analysis of current study. Supplementary Table S2 shows the full list of Go categories obtained from GSEA analysis of MSCs co-cultured with leukemic and normal CD34+ cells. Supplemental Table S3 shows the list of top-20 leading edge genes down-regulated in MSCs co-cultured with leukemia cells. Supplementary Table S4 shows the full list of AML patients enrolled in the cohort study to determine the association between stromal changes and clinical prognosis.
Supplemental Movie 3 from Full-Length Semaphorin-3C Is an Inhibitor of Tumor Lymphangiogenesis and Metastasis
Authors: Mumblat Yelena , Kessler Ofra , Ilan Neta , Neufeld Gera
Published: March 2023

Supplemental Movie 3. A time lapse movie of proliferating lymphatic endothelial cells (LEC).
Supplementary Figure Legends from STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma
Authors: Lau Jasmine , Ilkhanizadeh Shirin , Wang Susan , Miroshnikova Yekaterina A. , Salvatierra Nicolas A. , Wong Robyn A. , Schmidt Christin , Weaver Valerie M. , Weiss William A. , Persson Anders I.
Published: March 2023

Supplementary Figure Legends from STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma
Supplementary Materials and Methods from Cytosolic TMEM88 Promotes Invasion and Metastasis in Lung Cancer Cells by Binding DVLS
Authors: Zhang Xiupeng , Yu Xinmiao , Jiang Guiyang , Miao Yuan , Wang Liang , Zhang Yong , Liu Yang , Fan Chuifeng , Lin Xuyong , Dong Qianze , Han Qiang , Zhao Huanyu , Han Yong , Han Xu , Rong Xuezhu , Ding Shuting , Wang Endi , Wang Enhua
Published: March 2023

Supplementary Materials and Methods
Supplementary Figure Legend from Carbonic Anhydrase Activity Monitored In Vivo by Hyperpolarized 13C-Magnetic Resonance Spectroscopy Demonstrates Its Importance for pH Regulation in Tumors
Authors: Gallagher Ferdia A. , Sladen Helen , Kettunen Mikko I. , Serrao Eva M. , Rodrigues Tiago B. , Wright Alan , Gill Andrew B. , McGuire Sarah , Booth Thomas C. , Boren Joan , McIntyre Alan , Miller Jodi L. , Lee Shen-Han , Honess Davina , Day Sam E. , Hu De-En , Howat William J. , Harris Adrian L. , Brindle Kevin M.
Published: March 2023

Supplementary Figure Legend. Legend for Supplementary Figure S1.
Supplementary Figure Legends from Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors
Authors: Bagley Alexander F. , Scherz-Shouval Ruth , Galie Peter A. , Zhang Angela Q. , Wyckoff Jeffrey , Whitesell Luke , Chen Christopher S. , Lindquist Susan , Bhatia Sangeeta N.
Published: March 2023

Legend for Supplementary Figures S1-S10.
Supplementary Figure 3 from Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer
Authors: Takeuchi Shintaro , Baghdadi Muhammad , Tsuchikawa Takahiro , Wada Haruka , Nakamura Toru , Abe Hirotake , Nakanishi Sayaka , Usui Yuu , Higuchi Kohtaro , Takahashi Mizuna , Inoko Kazuho , Sato Syoki , Takano Hironobu , Shichinohe Toshiaki , Seino Ken-ichiro , Hirano Satoshi
Published: March 2023

Gemcitabine amplifies the expression of IL-6 or IL8 in Capan-1 cells.
Supplemental Table S2 from Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer
Authors: Du Juan , Cieslak John A. , Welsh Jessemae L. , Sibenaller Zita A. , Allen Bryan G. , Wagner Brett A. , Kalen Amanda L. , Doskey Claire M. , Strother Robert K. , Button Anna M. , Mott Sarah L. , Smith Brian , Tsai Susan , Mezhir James , Goswami Prabhat C. , Spitz Douglas R. , Buettner Garry R. , Cullen Joseph J.
Published: March 2023

Supplemental Table S2. Summary statistics for the survival analysis.
Supplemental Table S1 from Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer
Authors: Du Juan , Cieslak John A. , Welsh Jessemae L. , Sibenaller Zita A. , Allen Bryan G. , Wagner Brett A. , Kalen Amanda L. , Doskey Claire M. , Strother Robert K. , Button Anna M. , Mott Sarah L. , Smith Brian , Tsai Susan , Mezhir James , Goswami Prabhat C. , Spitz Douglas R. , Buettner Garry R. , Cullen Joseph J.
Published: March 2023

Supplemental Table S1. Summary statistics for tumor volume measurements in the mixed linear regression analysis in MIA PaCa-2 tumor xenografts.
Supplemental Figure S4 from Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer
Authors: Du Juan , Cieslak John A. , Welsh Jessemae L. , Sibenaller Zita A. , Allen Bryan G. , Wagner Brett A. , Kalen Amanda L. , Doskey Claire M. , Strother Robert K. , Button Anna M. , Mott Sarah L. , Smith Brian , Tsai Susan , Mezhir James , Goswami Prabhat C. , Spitz Douglas R. , Buettner Garry R. , Cullen Joseph J.
Published: March 2023

Supplemental Figure S4. Weight changes of mice during treatment periods.
Supplemental Figure S1 from Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer
Authors: Du Juan , Cieslak John A. , Welsh Jessemae L. , Sibenaller Zita A. , Allen Bryan G. , Wagner Brett A. , Kalen Amanda L. , Doskey Claire M. , Strother Robert K. , Button Anna M. , Mott Sarah L. , Smith Brian , Tsai Susan , Mezhir James , Goswami Prabhat C. , Spitz Douglas R. , Buettner Garry R. , Cullen Joseph J.
Published: March 2023

Supplemental Figure S1. Timing for the administration of pharmacological ascorbate enhances decreases in clonogenic survival.
Supplemental Figure Legends from Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer
Authors: Du Juan , Cieslak John A. , Welsh Jessemae L. , Sibenaller Zita A. , Allen Bryan G. , Wagner Brett A. , Kalen Amanda L. , Doskey Claire M. , Strother Robert K. , Button Anna M. , Mott Sarah L. , Smith Brian , Tsai Susan , Mezhir James , Goswami Prabhat C. , Spitz Douglas R. , Buettner Garry R. , Cullen Joseph J.
Published: March 2023

Supplemental Figure Legends. Legend for Supplemental Figures S1-S5.
Supplementary Figure Legend from Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models
Authors: Eberlein Catherine A. , Stetson Daniel , Markovets Aleksandra A. , Al-Kadhimi Katherine J. , Lai Zhongwu , Fisher Paul R. , Meador Catherine B. , Spitzler Paula , Ichihara Eiki , Ross Sarah J. , Ahdesmaki Miika J. , Ahmed Ambar , Ratcliffe Laura E. , O'Brien Elizabeth L. Christey , Barnes Claire H. , Brown Henry , Smith Paul D. , Dry Jonathan R. , Beran Garry , Thress Kenneth S. , Dougherty Brian , Pao William , Cross Darren A.E.
Published: March 2023

Supplementary Figure Legend. Legends for Supplementary Figures S1-S6.
Supplementary figure legends from Chemoradiotherapy-Induced Upregulation of PD-1 Antagonizes Immunity to HPV-Related Oropharyngeal Cancer
Authors: Parikh Falguni , Duluc Dorothée , Imai Naoko , Clark Amelia , Misiukiewicz Krzys , Bonomi Marcello , Gupta Vishal , Patsias Alexis , Parides Michael , Demicco Elizabeth G. , Zhang David Y. , Kim-Schulze Seunghee , Kao Johnny , Gnjatic Sacha , Oh Sangkon , Posner Marshall R. , Sikora Andrew G.
Published: March 2023

Supplementary figure legends
Supplementary Figure S1 from Improving Drug Penetrability with iRGD Leverages the Therapeutic Response to Sorafenib and Doxorubicin in Hepatocellular Carcinoma
Authors: Schmithals Christian , Köberle Verena , Korkusuz Hüdayi , Pleli Thomas , Kakoschky Bianca , Augusto Eduardo Alonso , Ibrahim Ahmed Atef , Arencibia Jose M. , Vafaizadeh Vida , Groner Bernd , Korf Horst-Werner , Kronenberger Bernd , Zeuzem Stefan , Vogl Thomas J. , Waidmann Oliver , Piiper Albrecht
Published: March 2023

Supplementary Figure S1: Imaging of HCC by Gd-EOB-DTPA-enhanced MRI in TGFα/c-myc mice with an HCC.
Supplementary Table S2 from Plasma Choline Metabolites and Colorectal Cancer Risk in the Women's Health Initiative Observational Study
Authors: Bae Sajin , Ulrich Cornelia M. , Neuhouser Marian L. , Malysheva Olga , Bailey Lynn B. , Xiao Liren , Brown Elissa C. , Cushing-Haugen Kara L. , Zheng Yingye , Cheng Ting-Yuan David , Miller Joshua W. , Green Ralph , Lane Dorothy S. , Beresford Shirley A.A. , Caudill Marie A.
Published: March 2023

ORs (95% CIs) of CRC by quartile of plasma DMG:choline ratio.
Supplementary Table S1 from Plasma Choline Metabolites and Colorectal Cancer Risk in the Women's Health Initiative Observational Study
Authors: Bae Sajin , Ulrich Cornelia M. , Neuhouser Marian L. , Malysheva Olga , Bailey Lynn B. , Xiao Liren , Brown Elissa C. , Cushing-Haugen Kara L. , Zheng Yingye , Cheng Ting-Yuan David , Miller Joshua W. , Green Ralph , Lane Dorothy S. , Beresford Shirley A.A. , Caudill Marie A.
Published: March 2023

ORs (95% CIs) of CRC by quartile of plasma DMG.
Supplementary Figure 2 from c-Myc Alterations Confer Therapeutic Response and Acquired Resistance to c-Met Inhibitors in MET-Addicted Cancers
Authors: Shen Aijun , Wang Lu , Huang Min , Sun Jingya , Chen Yi , Shen Yan-Yan , Yang Xinying , Wang Xin , Ding Jian , Geng Meiyu
Published: March 2023

Supplementary Figure 2-c-Myc downregulation is essential for c-Met inhibition caused growth arrest in MET-addicted cells.
Supplemental Figure 6 from Mig-6 Suppresses Endometrial Cancer Associated with Pten Deficiency and ERK Activation
Authors: Kim Tae Hoon , Yoo Jung-Yoon , Kim Hong Im , Gilbert Jenifer , Ku Bon Jeong , Li Jane , Mills Gordon B. , Broaddus Russell R. , Lydon John P. , Lim Jeong Mook , Yoon Ho-Geun , Jeong Jae-Wook
Published: March 2023

Supplemental Figure 6. MIG-6 interacts with ERK2 via its SH3 binding domain.
Supplemental File 1 from CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110
Authors: Hu Shanhu , Danilov Alexey V. , Godek Kristina , Orr Bernardo , Tafe Laura J. , Rodriguez-Canales Jaime , Behrens Carmen , Mino Barbara , Moran Cesar A. , Memoli Vincent A. , Mustachio Lisa Maria , Galimberti Fabrizio , Ravi Saranya , DeCastro Andrew , Lu Yun , Sekula David , Andrew Angeline S. , Wistuba Ignacio I. , Freemantle Sarah , Compton Duane A. , Dmitrovsky Ethan
Published: March 2023

Supplemental File S1. The siRNA sequences and real-time qPCR primer sequences.
Supplemental Figure 4 from CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110
Authors: Hu Shanhu , Danilov Alexey V. , Godek Kristina , Orr Bernardo , Tafe Laura J. , Rodriguez-Canales Jaime , Behrens Carmen , Mino Barbara , Moran Cesar A. , Memoli Vincent A. , Mustachio Lisa Maria , Galimberti Fabrizio , Ravi Saranya , DeCastro Andrew , Lu Yun , Sekula David , Andrew Angeline S. , Wistuba Ignacio I. , Freemantle Sarah , Compton Duane A. , Dmitrovsky Ethan
Published: March 2023

Supplemental Fig. S4. (A) Effect of engineered KRAS expression on response to CDK2 inhibition by seliciclib. KRAS mutation sensitized lung cancer cells towards seliciclib-mediated CDK2 inhibition of growth as compared to control-ED-1 cells. (B) Cells transfected with the plasmid expressing HA-tagged human CP110 were used for detection of CP110 using an anti-CP110 antibody (1:1000) and an anti-HA antibody (1:1000), respectively. The upper band detected by the anti-CP110 antibody specifically recognizes CP110. (C) Respective CP110 and RAS protein expression profile in murine lung cancer cell lines is shown. (D) Effect of KRAS knockdown at 48 hours (left panel) and 72 hours (right panel) on CP110 expression in the 344P cell line. (E) Effect of KRAS knockdown at 72 hours (left panel) and 96 hours (right panel) on CP110 expression in the Hop62 cell line.
Supplementary Methods and References from Tropomodulin 1 Expression Driven by NF-κB Enhances Breast Cancer Growth
Authors: Ito-Kureha Taku , Koshikawa Naohiko , Yamamoto Mizuki , Semba Kentaro , Yamaguchi Noritaka , Yamamoto Tadashi , Seiki Motoharu , Inoue Jun-ichiro
Published: March 2023

Supplementary Methods and References. Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplementary Figure 7 from Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells
Authors: Lo Albert , Wang Liang-Chuan S. , Scholler John , Monslow James , Avery Diana , Newick Kheng , O'Brien Shaun , Evans Rebecca A. , Bajor David J. , Clendenin Cynthia , Durham Amy C. , Buza Elizabeth L. , Vonderheide Robert H. , June Carl H. , Albelda Steven M. , Puré Ellen
Published: March 2023

Identification of tumor stroma by FAP and SMA reveals stromal cell heterogeneity in human and murine PDA.
Supplemental Figure Legend from TP53 Silencing Bypasses Growth Arrest of BRAFV600E-Induced Lung Tumor Cells in a Two-Switch Model of Lung Tumorigenesis
Authors: Shai Anny , Dankort David , Juan Joseph , Green Shon , McMahon Martin
Published: March 2023

Supplemental Figure Legend
Supp. Figure 5 from LIM Kinase Inhibitor Pyr1 Reduces the Growth and Metastatic Load of Breast Cancers
Authors: Prunier Chloé , Josserand Véronique , Vollaire Julien , Beerling Evelyne , Petropoulos Christos , Destaing Olivier , Montemagno Christopher , Hurbin Amandine , Prudent Renaud , de Koning Leanne , Kapur Reuben , Cohen Pascale A. , Albiges-Rizo Corinne , Coll Jean-Luc , van Rheenen Jacco , Billaud Marc , Lafanechère Laurence
Published: March 2023

RPPA results of tubulin acetylation, tubulin detyrosination and cofilin phosphorylation levels in tumors of mice treated with vehicle, Pyr1 and PTX
Supplementary Methods from Tumor-Specific Effector CD8+ T Cells That Can Establish Immunological Memory in Humans after Adoptive Transfer Are Marked by Expression of IL7 Receptor and c-myc
Authors: Chandran Smita S. , Paria Biman C. , Srivastava Abhishek K. , Rothermel Luke D. , Stephens Daniel J. , Kammula Udai S.
Published: March 2023

Supplementary Methods: Detailed information regarding additional materials and methods.
Supplemental Figures 1-9 and Tables 1 and 2 from FOXP3 Controls an miR-146/NF-κB Negative Feedback Loop That Inhibits Apoptosis in Breast Cancer Cells
Authors: Liu Runhua , Liu Cong , Chen Dongquan , Yang Wei-Hsiung , Liu Xiuping , Liu Chang-Gong , Dugas Courtney M. , Tang Fei , Zheng Pan , Liu Yang , Wang Lizhong
Published: March 2023

Supplemental Figures 1-9 and Tables 1 and 2. Supplemental Table 1: Identification of potential FOXP3-targeted microRNAs in breast cancer cells. Supplemental Table 2: Primer sequences used in this study. Supplemental Figure 1: Expression profiles of IRAK1 and TRAF6 in MCF10A cells with miR-146a/b inhibitors. Supplemental Figure 2: Expression of nuclear FOXP3 in FOXP3-Tet-off MCF7 cells. Supplemental Figure 3: The expression profile of NF-κB target genes after FOXP3 induction in FOXP3-Tet-off MCF7 cells. Supplemental Figure 4: Identification of potential FOXP3-binding sites in promoter regions of miR-146a/b in the FOXP3-Tet-off MCF7 cells by whole-genome ChIP-seq. Supplemental Figure 5: Quantitative analysis of FOXP3-binding sites in the potential promoter region of human miR-146b in FOXP3-Tet-off MCF7 cells. Supplemental Figure 6: Specific binding of FOXP3 to the second forkhead-binding motif (GCAAATA) in the miR-146a promoter. Supplemental Figure 7: MiR-146a/b upregulation by FOXP3 transfection in MDA-MB231 cells. Supplemental Figure 8: The mRNA expression levels of IRAK1and TRAF6 in metastatic breast tumor cells after administration of miR-146a/b inhibitors. Supplemental Figure 9: A potential mechanism by which FOXP3 regulates the NF-κB-miR-146a/b feedback loop through IRAK1 and TRAF6 in tumor growth or regulates CXCR4/MMP9 in tumor metastasis.
Supplemental Figure 4 from CSF1 Receptor Targeting in Prostate Cancer Reverses Macrophage-Mediated Resistance to Androgen Blockade Therapy
Authors: Escamilla Jemima , Schokrpur Shiruyeh , Liu Connie , Priceman Saul J. , Moughon Diana , Jiang Ziyue , Pouliot Frederic , Magyar Clara , Sung James L. , Xu Jingying , Deng Gang , West Brian L. , Bollag Gideon , Fradet Yves , Lacombe Louis , Jung Michael E. , Huang Jiaoti , Wu Lily
Published: March 2023

Splenic macrophages expand upon castration.
Supplemental Figure 1 from CSF1 Receptor Targeting in Prostate Cancer Reverses Macrophage-Mediated Resistance to Androgen Blockade Therapy
Authors: Escamilla Jemima , Schokrpur Shiruyeh , Liu Connie , Priceman Saul J. , Moughon Diana , Jiang Ziyue , Pouliot Frederic , Magyar Clara , Sung James L. , Xu Jingying , Deng Gang , West Brian L. , Bollag Gideon , Fradet Yves , Lacombe Louis , Jung Michael E. , Huang Jiaoti , Wu Lily
Published: March 2023

The prominent presence of macrophages in Myc-CaP tumors.
Figure S6 from ERAP1 Regulates Natural Killer Cell Function by Controlling the Engagement of Inhibitory Receptors
Authors: Cifaldi Loredana , Romania Paolo , Falco Michela , Lorenzi Silvia , Meazza Raffaella , Petrini Stefania , Andreani Marco , Pende Daniela , Locatelli Franco , Fruci Doriana
Published: March 2023

Supplementary Figure S6 shows KIR-Fc binding and the percentage of CD107a+ NK cells in response to Leu-SH and DTT-treated DAOY cells.
Figure S5 from ERAP1 Regulates Natural Killer Cell Function by Controlling the Engagement of Inhibitory Receptors
Authors: Cifaldi Loredana , Romania Paolo , Falco Michela , Lorenzi Silvia , Meazza Raffaella , Petrini Stefania , Andreani Marco , Pende Daniela , Locatelli Franco , Fruci Doriana
Published: March 2023

Supplementary Figure S5 shows surface expression of ligands for activating NK cell receptors on DAOY cells treated with ERAP1 inhibitor
Supplementary Figures 1 - 8 from PARD3 Inactivation in Lung Squamous Cell Carcinomas Impairs STAT3 and Promotes Malignant Invasion
Authors: Bonastre Ester , Verdura Sara , Zondervan Ilse , Facchinetti Federica , Lantuejoul Sylvie , Chiara Maria Dolores , Rodrigo Juan Pablo , Carretero Julian , Condom Enric , Vidal Agustin , Sidransky David , Villanueva Alberto , Roz Luca , Brambilla Elisabeth , Savola Suvi , Sanchez-Cespedes Montse
Published: March 2023

Figure S1. PARD3-inactivation in the H157 lung cancer cell line. Figure S2. Ratio charts of the multiplex ligation-dependent probe amplification (MLPA) depicting a large intragenic deletion (from exon 4 to 23) in one of the LSCCs but not a normal DNA. Figure S3. Methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA) to determine the presence of promoter hypermethylation of PARD3. Figure S4. Relative abundance of the PARD3 transcriptsFigure S5. Western blot showing ectopic and transient expression of the indicated PAR3 proteins in the H157 cell line, immunoblotted with HA or PAR3 antibodies. Figure S6. Immunofluorescence with the anti-PAR3 antibody in the indicated T98G-derived cells, after (Dox+) induction of PAR3 expression with doxycycline (1 ng/µl, 24h). Scale bar, 50 µm. Figure S7. Western blot depicts the endogenous PAR3 protein in the indicated lung cancer cells and the ectopic expression of PAR3 in the H157tr-pD41_R74del cells (dox, 1 ng/µl; 24 h). Figure S8. Immunostaining of PAR3 in lung primary tumors and head and neck squamous cell carcinomas (HNSCCs).
Supplementary Figures S1-S2 from Identification of Variant-Specific Functions of PIK3CA by Rapid Phenotyping of Rare Mutations
Authors: Dogruluk Turgut , Tsang Yiu Huen , Espitia Maribel , Chen Fengju , Chen Tenghui , Chong Zechen , Appadurai Vivek , Dogruluk Armel , Eterovic Agna Karina , Bonnen Penelope E. , Creighton Chad J. , Chen Ken , Mills Gordon B. , Scott Kenneth L.
Published: March 2023

MCF10A cell growth is dependent on insulin and epidermal growth factor (S1); RPPA analysis (S2).
Supplementary Table S2 from Enhanced Histone Deacetylase Activity in Malignant Melanoma Provokes RAD51 and FANCD2-Triggered Drug Resistance
Authors: Krumm Andrea , Barckhausen Christina , Kücük Pelin , Tomaszowski Karl-Heinz , Loquai Carmen , Fahrer Jörg , Krämer Oliver Holger , Kaina Bernd , Roos Wynand Paul
Published: March 2023

Real-time PCR array results showing changes in expression of the listed genes. HDACs were inhibited by VPA (1 mM for 168 h) in D05 cells and fold change in gene expression was calculated compared to untreated controls.
Supplementary Figure Legends from Genomic Profiling of Penile Squamous Cell Carcinoma Reveals New Opportunities for Targeted Therapy
Authors: McDaniel Andrew S. , Hovelson Daniel H. , Cani Andi K. , Liu Chia-Jen , Zhai Yali , Zhang Yajia , Weizer Alon Z. , Mehra Rohit , Feng Felix Y. , Alva Ajjai S. , Morgan Todd M. , Montgomery Jeffrey S. , Siddiqui Javed , Sadis Seth , Bandla Santhoshi , Williams Paul D. , Cho Kathleen R. , Rhodes Daniel R. , Tomlins Scott A.
Published: March 2023

Legends for Supplementary Figures S1-S5.
Supplementary Table S2 from Diverse Targets of β-Catenin during the Epithelial–Mesenchymal Transition Define Cancer Stem Cells and Predict Disease Relapse
Authors: Chang Yi-Wen , Su Ying-Jhen , Hsiao Michael , Wei Kuo-Chen , Lin Wei-Hsin , Liang Chi-Jung , Chen Shin-Cheh , Lee Jia-Lin
Published: March 2023

Supplementary Table S2: β-catenin ChIP-seq alignment results in HM20 cells
Supplementary Figure S8 from Diverse Targets of β-Catenin during the Epithelial–Mesenchymal Transition Define Cancer Stem Cells and Predict Disease Relapse
Authors: Chang Yi-Wen , Su Ying-Jhen , Hsiao Michael , Wei Kuo-Chen , Lin Wei-Hsin , Liang Chi-Jung , Chen Shin-Cheh , Lee Jia-Lin
Published: March 2023

Supplementary Figure S8: Model proposing a pathway that the EMT acts as a molecular switch for Wnt/β-catenin-elicited promotion of the CSC phenotype.
Supplementary Figure 1 from Ibrutinib Exerts Potent Antifibrotic and Antitumor Activities in Mouse Models of Pancreatic Adenocarcinoma
Authors: Massó-Vallés Daniel , Jauset Toni , Serrano Erika , Sodir Nicole M. , Pedersen Kim , Affara Nesrine I. , Whitfield Jonathan R. , Beaulieu Marie-Eve , Evan Gerard I. , Elias Laurence , Arribas Joaquín , Soucek Laura
Published: March 2023

Mouse weights for all experiments.
Supplementary Figure S5 from Diverse Targets of β-Catenin during the Epithelial–Mesenchymal Transition Define Cancer Stem Cells and Predict Disease Relapse
Authors: Chang Yi-Wen , Su Ying-Jhen , Hsiao Michael , Wei Kuo-Chen , Lin Wei-Hsin , Liang Chi-Jung , Chen Shin-Cheh , Lee Jia-Lin
Published: March 2023

Supplementary Figure S5: Tandem co-IP and re-ChIP experiments using CL1-0 and CL1-5 cells.
Supplementary Table S2 from The miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells during Carcinogenesis
Authors: Riesco-Eizaguirre Garcilaso , Wert-Lamas León , Perales-Patón Javier , Sastre-Perona Ana , Fernández Lara P. , Santisteban Pilar
Published: March 2023

Over-represented gene sets defined in KEGG (Kyoto Encyclopedia of Genes and Genomes) amongst differentially expressed genes in PTC.
Supplementary Table S3 from Pulsed High-Intensity Focused Ultrasound Enhances Delivery of Doxorubicin in a Preclinical Model of Pancreatic Cancer
Authors: Li Tong , Wang Yak-Nam , Khokhlova Tatiana D. , D'Andrea Samantha , Starr Frank , Chen Hong , McCune Jeannine S. , Risler Linda J. , Mashadi-Hossein Afshin , Hingorani Sunil R. , Chang Amy , Hwang Joo Ha
Published: March 2023

Supplementary Table S3. Estimated regression coefficients from equation s1.