bluuebunny/crossref_metadata_2025 huggingface dataset:
Preventive interventions to improve older people’s health outcomes: systematic review and meta-analysis
Authors: Palapar Leah , Blom Jeanet W , Wilkinson-Meyers Laura , Lumley Thomas , Kerse Ngaire
Published: October 2023

Background

Systematic reviews of preventive, non-disease-specific primary care trials for older people often report effects according to what is thought to be the intervention’s active ingredient.

Aim

To examine the effectiveness of preventive primary care interventions for older people and to identify common components that contribute to intervention success.

Design and setting

A systematic review and meta-analysis of 18 randomised controlled trials (RCTs) published in 22 publications from 2009 to 2019.

Method

A search was conducted in PubMed, MEDLINE, Embase, Web of Science, CENTRAL, CINAHL, and the Cochrane Library. Inclusion criteria were: sample mainly aged ≥65 years; delivered in primary care; and non-disease-specific interventions. Exclusion criteria were: non-RCTs; primarily pharmacological or psychological interventions; and where outcomes of interest were not reported. Risk of bias was assessed using the original Cochrane tool. Outcomes examined were healthcare use including admissions to hospital and aged residential care (ARC), and patient-reported outcomes including activities of daily living (ADLs) and self-rated health (SRH).

Results

Many studies had a mix of patient-, provider-, and practice-focused intervention components (13 of 18 studies). Studies included in the review had low-to-moderate risk of bias. Interventions had no overall benefit to healthcare use (including admissions to hospital and ARC) but higher basic ADL scores were observed (standardised mean difference [SMD] 0.21, 95% confidence interval [CI] = 0.01 to 0.40) and higher odds of reporting positive SRH (odds ratio [OR] 1.17, 95% CI = 1.01 to 1.37). When intervention effects were examined by components, better patient-reported outcomes were observed in studies that changed the care setting (SMD for basic ADLs 0.21, 95% CI = 0.01 to 0.40; OR for positive SRH 1.17, 95% CI = 1.01 to 1.37), included educational components for health professionals (SMD for basic ADLs 0.21, 95% CI = 0.01 to 0.40; OR for positive SRH 1.27, 95% CI = 1.05 to 1.55), and provided patient education (SMD for basic ADLs 0.28, 95% CI = 0.09 to 0.48). Additionally, admissions to hospital in intervention participants were fewer by 23% in studies that changed the care setting (incidence rate ratio [IRR] 0.77, 95% CI = 0.63 to 0.95) and by 26% in studies that provided patient education (IRR 0.74, 95% CI = 0.56 to 0.97).

Conclusion

Preventive primary care interventions are beneficial to older people’s functional ability and SRH but not other outcomes. To improve primary care for older people, future programmes should consider delivering care in alternative settings, for example, home visits and phone contacts, and providing education to patients and health professionals as these may contribute to positive outcomes.
Older adults’ perceptions of navigating eye health care in Denmark: a qualitative study
Authors: Sandholdt Catharina Thiel , Jacobsen Marie Honoré , Mathiesen Olivia Hjulsager , Jønsson Alexandra Brandt Ryborg , Jensen Andrea Nedergaard , Steinbo Emma Katrine Frøhlke , Reventlow Susanne , Waldorff Frans Boch
Published: October 2023

Background

Vision impairment can have an impact on cognition, health, and social function. Vision loss may be avoided if detected early and treated promptly. Eye health is a minor topic in general practice, but the ongoing relationship between doctor and patient has the potential to assist the patient in navigating the healthcare system and guaranteeing timely healthcare service delivery.

Aim

To explore the attitudes of older members of the public (aged ≥60 years) towards navigating primary sector eye health care in Denmark, with a focus on optometrists, practising ophthalmologists (POs), and GPs.

Design & setting

Qualitative study in Copenhagen, Denmark.

Method

Focus group interviews were performed in the spring of 2022 with 21 older members of the public.

Results

Older members of the public perceived optometrists and POs to be the most relevant health professionals to consult about eye health. Opportunities were identified for enhancing the function of general practice including detecting early signs of visual impairment, being in charge of further referrals, and managing issues affecting quality of life such as dry eyes.

Conclusion

Older members of the public sought help from health professionals who are directly qualified to treat symptoms of vision impairment that patients are experiencing or expect to face in the near future. Participants identified a potential for GPs to address vision impairment. This included focusing on the patient’s general health and function, as well as potential comorbidities influencing treatment trajectories. The current denigration of general practice risks missing out on the potential benefits of robust engagement from general practice in eye health.
O papel da vitamina D na regulação do ciclo sono-vigília
Authors: Moreira Danilo José Silva , Vasconcelos Suzana dos Santos , Oliveira Vinicius Faustino Lima de , Fonseca Juliana Brito da , Rossi Karoline , Ferreira Elane de Nazaré Magno
Published: October 2023

Introdução. A vitamina D exerce diversas funções no organismo, incluindo a regulação do ciclo sono-vigília, visto que sua deficiência está associada a distúrbios do sono. Entretanto, os mecanismos biológicos para esse controle não são totalmente conhecidos. Objetivo. Analisar os principais mecanismos de atuação da vitamina D na regulação do ciclo sono-vigília. Método. Revisão integrativa da literatura, realizada com pesquisa bibliográfica nas bases de dados Scielo, Pubmed e Biblioteca Virtual em Saúde, com os seguintes descritores retirados das plataformas DeCS e MeSH: “vitamin D”, “sleep”, “vitamina D” e “sono”. Foram incluídos trabalhos publicados nos últimos 5 anos e com textos completos. Resultados. Após revisão pormenorizada dos 476 resultados obtidos, foram selecionados 23 artigos para compor esta revisão. As principais hipóteses encontradas para explicar a regulação da vitamina D sobre o ciclo sono-vigília incluíram sua participação na síntese de melatonina e de neurotransmissores essenciais para as vias neurais envolvidas no ciclo sono-vigília, assim como no desenvolvimento dos neurônios que integram essas vias. Ademais, postula-se seu papel na modulação imunológica e na desintoxicação do sistema nervoso central. Conclusão. Evidencia-se a importância de compreender os possíveis mecanismos de regulação do ciclo sono-vigília pela vitamina D, principalmente pela possibilidade de explorar a fisiopatologia dos distúrbios do sono. Porém, mais estudos são necessários para esclarecer outros possíveis mecanismos de regulação.
Novel 2-Amino-pyrano[3,2-c]quinoline-3-carbonitrile Derivatives Bearing Benzyloxy Phenyl Moiety as Butyrylcholinesterase Inhibitors: Design, Synthesis, In Vitro Evaluation, and Molecular Docking Studies
Authors: Chehardoli Gholamabbas , Karimi Fatemeh , Akbarzadeh Tahmineh , Hariri Roshanak , Najafi Zahra
Published: October 2023

Background: Alzheimer’s disease (AD), the main form of dementia, is a multifactorial neurodegenerative disease, and several hypotheses have been proposed for its pathogenesis. Among them, cholinergic hypofunction is the main reason and plays a significant role in cognitive impairment. According to this theory, ChE inhibitors improve the performance of the cholinergic system and increase memory function. Thus, this study investigated a novel series of 2-amino-pyrano[3,2-c]quinoline-3-carbonitrile derivatives bearing benzyloxy phenyl moiety as ChE enzyme inhibitors. Methods: The synthesized compounds 6a-o are divided into three series based on benzyloxy phenyl moiety. The structure of all compounds was identified by the NMR (1 H and 13C) and IR spectra. Then, their inhibitory activities against ChE enzymes were evaluated by Ellman’s spectrophotometrical method. The kinetic and molecular docking studies were performed for compound 6l as the most potent butyrylcholinesterase (BChE) inhibitor. Results: The 2-amino-4-(4-((4-fluorobenzyl)oxy)-3-methoxyphenyl)-5-oxo-5,6-dihydro-4H-pyrano[3,2-c] quinoline-3-carbonitrile (6l) demonstrated the best anti-BChE activity with a half maximal inhibitory concentration value of 1.00±0.07. The kinetic and molecular docking studies confirmed that 6l is a mixed inhibitor and binds to both the anionic catalytic site and peripheral anionic site (PAS) of BChE. In silico study approved that the methoxy group on the middle phenyl ring has a significant role in interacting with the PAS of the enzyme. Conclusion: These findings indicated that 2-amino-pyrano[3,2-c]quinoline-3-carbonitrile derivatives bearing benzyloxy phenyl moiety have therapeutic potential as BChE inhibitors in the last stages of AD.
Promotion of Possible Protective Methods for Farmers During Exposure to Pesticides (Diazinon): A Policy Summary
Authors: Mehri Fereshteh , Alafchi Behnaz , Shiri Elham , Afzali Saeed
Published: October 2023

According to the estimates of the World Health Organization (WHO), more than three million poisonings with organophosphorus derivatives occur every year, and in the meantime, more than 250000 deaths will occur in the future. Globally, 30% of suicide cases occur with the use of organophosphorus derivatives. Organophosphorus toxins are widely used due to their stability and low cumulative effects on the ecosystem. Diazinon, as one of the organophosphates, is widely utilized in agriculture and veterinary medicine. This poison is highly toxic to humans and animals. As stated by various studies, stores of unauthorized supply of poisons and lack of proper monitoring of the permissible limit of poisons, as well as the sale of poisons without a prescription, farmers’ ignorance, and indiscriminate planting of crops that are not based on traditional agriculture, can be caused by various factors related to improper use. In addition, the excessive use of pesticides and agricultural poisons can cause short- and long-term effects on health. Enhancing the antioxidant capacity is an effective solution to weaken the toxic effects of diazinon. Garlic and garlic supplements are used in many countries for their blood lipid-lowering, anti-platelet effects, and beneficial blood circulation. Some garlic products seem to have liver-protective, immune-system-enhancing, and anticancer, chemical-preventive, and antioxidant activities. The anti-inflammatory and antioxidant effects of garlic oil have been shown in different tissues. In today’s world, an effective solution/ decision-making for such problems based on evidence is recommended by compiling a policy brief. Therefore, to demonstrate evidence-based policy options, taking into account the existing obstacles and opportunities, it seems necessary to use intervention strategies and planning to reduce the consumption of pesticides and increase the level of protection for farmers.
In Vivo Coagulation Effects of Thymus vulgaris Leaves Extract in Mice
Authors: Mashkani Zahra Sadat , Vatandoost Jafar , Hajjar Toktam , Mahdavi Behnam
Published: October 2023

Background: In addition to current therapies, herbal medicine is still used as an effective method for the treatment of some diseases such as bleeding disorders. Thymus vulgaris has been employed as traditional remedy in the treatment of bleeding disorders, although its clinical effects have not been investigated yet. Accordingly, this study evaluated the effects of the T. vulgaris extract on coagulation parameters, including bleeding time (BT), clotting time (CT), prothrombin time (PT), activated partial thromboplastin time (aPTT), and the number of platelets (PLT). Methods: Forty male mice were randomly divided into 5 groups (n=8). The treated groups were administered with 100, 200, or 300 mg/kg/daily of the hydroalcoholic extract, as well as negative and positive control groups. Blood samples were taken from animals on the 13th and 14th day after treatment, and then coagulation indices were determined finally. Results: The results demonstrated a significant reduction in the BT and CT tests while a significant increase in PT, aPTT, and platelet numbers. Phenolic and flavonoid compounds in the hydro-alcoholic extract of T. vulgaris are the most affecting compounds confirmed by gas chromatography-mass spectrometry and phytochemical experiments. Conclusion: In general, the results indicated the coagulation effect of the T. vulgaris extract through primary homeostasis and a common pathway of secondary hemostasis.
Izrada kroja korzeta
s košaricama-online učenje
Authors: Kocijančić Đurđica
Published: October 2023

U radu je prikazana izrada kroja korzeta s košaricama prilagođena online učenju na kolegiju ‘’Izrada kostima (workshop)’’. Postupak izrade kroja ženskog korzeta s košaricama se temelji na posebnom načinu opisanom u radu. Rad je sažetak foto lekcija online nastave iz vježbi. Ovaj rad ima za cilj objasniti na koji se način izrađuje kroj korzeta s košaricama putem online nastave studentima smjera Kostimografije za vrijeme kada nije moguća kontaktna nastava. Posebnim načinom je prikazan detaljan svaki krojni dio u mjerilu 1:1 kako bi se prema uputama mogao izraditi kroj korzeta s košaricama. Na taj se način može usmjeriti studente smjera Kostimografije da prema točnim uputama putem online nastave izrade korzet kod kuće.
2-Aminopiridin türevleri ile 2-metoksi-5-sülfamoyilbenzoik asit tuzlarının sentezi, karakterizasyonu, antimikrobiyal aktivitelerinin incelenmesi
Authors: İLKİMEN Halil , YENİKAYA Cengiz , GÜLBANDILAR Aysel
Published: October 2023

Bu çalışmada, 2-metoksi-5-sülfamoyilbenzoik asit (Hsba) ile 2-aminopiridin (ap), 2-benzilaminopiridin (2Bzap), 2-aminometilpiridin (2amp) ve 2-amino-3-hidroksipiridin (2a3OHp)’in proton transfer tuzları (2apsba, 2Bzapsba, 2ampsba ve 2a3OHpsba) sentezlenmiştir. Başlangıç maddeleri ve proton transfer tuzlarının Enterococcus faecalis (ATCC 29212), Listeria monocytogenes (ATCC 7644), Bacillus subtilis, Staphylococcus aureus (NRRL-B 767) (Gram pozitif), Escherichia coli (ATCC 25922) ve Pseudomonas aeruginosa (ATCC 27853) (Gram negatif) bakterilerine ve Candida Albicans (ATCC 14053) mayasına karşı antibakteriyel ve antifungal aktiviteleri incelenmiştir. Antifungal aktiviteler Flukonazol ile antibakteriyel aktiviteleri ise Sefepim, Vankomisin ve Levofloksasin ile kıyaslanmıştır. Deneyde kullanılan ve sentezlenen bileşikler bakteri ve mayalara karşı aktiviteye sahiptir. Bileşiklerin en iyi aktivite değerleri B. subtilis bakterisinde 2Bzap ve 2a3OHp (31,25 µg/mL), E. faecalis ve S. aureus bakterilerinde tüm bileşikler (Hsba hariç) (62,50 µg/mL), E. coli bakterisinde 2a3OHpsba (15,60 µg/mL), L. monocytogenes bakterisinde Hsba, 2Bzap, 2amp ve 2a3OHp (31,25 µg/mL), P. aeruginoa bakterisinde Hsba (31,25 µg/mL) ve C. albicans mayasında 2Bzap (31,25 µg/mL)’de gözlenmiştir.
Penerapan Pendidikan Teknologi Menurut Yuval Noah Harari di Indonesia
Authors: Kareli Vincentius Yossy , Utomo Kurniawan Dwi Madyo
Published: October 2023

Pendidikan termasuk dalam bidang pembinaan sentral manusia. Manusia telah memasuki dunia pendidikan sedari ia lahir hingga menjelang kematiannya. Pendidikan adalah salah satu upaya bagi manusia untuk mewujudkan eksistensinya di dunia. Pendidikan abad 21 tengah diwarnai dengan banyak kemajuan teknologi yang juga memberi dampak tersendiri bagi pendidikan dan usaha realisasi eksistensi peserta didik. Lembaga pendidikan dari semua jenjang perlu memperhatikan fakta tersebut supaya mampu merancang peta pendidikan yang tepat guna dan menghasilkan generasi yang mampu beradaptasi di era disrupsi teknologi. Dalam penelitian ini penulis memaparkan secara ringkas pendidikan teknologi menurut Yuval Noah Harari dan penerapannya di Indonesia. Metode yang digunakan dalam penelitian ini adalah studi literatur, dengan menggunakan sumber-sumber relevan dan kredibel seperti buku, jurnal, dan media massa elektronik. Penelitian ini menemukan bahwa pendidikan teknologi menurut Harari berfokus pada pembinaan karakter, pengembangan literasi teknologi peserta didik, serta pendalaman kompetensi kolaboratif-kooperatif dan sangat relevan diterapkan di Indonesia.
Istilah Rosario: Suatu Metafora
Authors: Pasi Gregorius
Published: October 2023

Abstract

The rosary is a simple but rich form of marian devotion. This article is intended to present one of these riches, namely the term of rosary itself. Therefore, the title of this article is: “The Term of Rosary: A Metaphor”. The focus of this article is to answer the following two questions. First, what is the impact of using the term of rosary on the marian devotees? Second, how can the term of rosary have an impact on the marian devotees? In order to answer these questions, we use the critical analysis and critical dialectic on the elements related to the theme of this research. Through this critical analysis  and dialectical analysis we found the following two things: first, metaphor can transforms the marian devotee’s understanding, feelings dan attitudes towards the marian devotion intended by the metaphor the rosary; secondly,  for the metaphor to have an impact on marian devotees, they must first realize that the term is a metaphor not only in the broad sense, but also in the strict sense, besides that, the marian devotees must have an experince related to a rose garden (rosarium) or roses (rosa).

     

Abstrak

Rosario merupakan suatu bentuk devosi marial yang sederhana namun kaya. Tulisan ini dimaksudkan untuk menampilkan salah satu kekayaan itu, yaitu istilah “rosario” itu sendiri. Karena itu, judul tulisan adalah: “Istilah Rosario: Suatu Metafora”. Fokus tulisan ini adalah menjawab kedua pertanyaan berikut. Pertama, apa dampak penggunaan istilah “rosario” bagi para devosan marial? Kedua, bagaimana supaya istilah rosario itu berdampak pada para devosan marial? Dalam rangka menjawab pertanyaan itu, kami menggunakan metode analisis kritis dan dialektika kritis atas unsur-unsur terkait tema penelitian ini. Melalui analisis kritis dan dialektika itu, kami menemukan kedua hal berikut: pertama, metafora dapat mentransformasi pemahaman, perasaan dan sikap devosan marial terhadap bentuk devosi marial yang dimaksudkan dengan metafora itu; kedua, agar metafora itu berdampak pada para dovosan marial, pertama-tama mereka harus menyadari bahwa istilah itu merupakan suatu metafora, bukan hanya dalam arti luas, tetapi juga dalam arti sempit; selain itu, para devosan marial harus memiliki pengalaman terkait dengan taman mawar (rosarium) atau mawar (rosa).

Kata Kunci: Rosario, metafora, devosi marial, Mazmur, transformasi.
Addressing Learning Difficulties in Junior High School Physics Education: Insights for Curriculum Development and Teaching Strategies
Authors: Shrestha Polanski Snyder , Perlman Tancredi Thorne , Shaver Scuka Rousseau
Published: October 2023

This research delves into the intricate analysis of students' learning difficulties in comprehending physics material at the junior high school level. Through a comprehensive investigation involving mixed-methods research, encompassing both qualitative and quantitative approaches, the study sought to identify prevalent misconceptions, cognitive barriers, and socio-economic factors influencing students' understanding of fundamental physics concepts. The research illuminated the pervasive misconceptions encountered by students, particularly in areas related to force and motion, energy conservation, wave behavior, electricity, and abstract concepts in quantum physics. Cognitive barriers, stemming from the abstract nature of physics principles and the incongruence with everyday experiences, posed significant challenges for students in comprehending these complex concepts. Insights from this research emphasized the critical need for innovative pedagogical approaches, integrated with real-world applications, to bridge the gap between abstract scientific principles and students' experiences. Curriculum reforms aimed at contextualizing physics concepts and accommodating diverse learning styles were identified as crucial for fostering an engaging and effective learning environment. Moreover, the study shed light on socio-economic disparities that influenced students' readiness and access to resources, advocating for equity in educational support and opportunities. The findings from this research have far-reaching implications, calling for systemic changes in teaching methodologies, curriculum design, and policy initiatives to enhance the learning experience in physics education. The research serves as a beacon for educators, curriculum developers, and policymakers, guiding them toward transformative changes essential for nurturing a generation of students equipped with a deeper understanding of fundamental scientific principles in physics.
The Impact of Smartphone Use on Students' Motor Skills and Emotional Well-being: A Comprehensive Study
Authors: Tigor Methodius , Simbolon Agata Putri Handayani
Published: October 2023

The widespread adoption of smartphones among students has raised intriguing questions about their potential influence on various aspects of development, including motor skills and emotional well-being. This research undertook a comprehensive investigation into these relationships, employing a mixed-methods approach encompassing surveys, interviews, and observational assessments. The findings revealed a complex interplay between smartphone use and motor skills. While certain aspects of motor development exhibited negative associations with prolonged smartphone usage, nuances emerged when considering the types of activities engaged in and the presence of parental guidance. These results underscore the significance of maintaining a balanced approach to technology use that encourages physical activity alongside screen time. In the realm of emotional well-being, this study unveiled a spectrum of effects associated with smartphone use. While some students reported experiencing stress, anxiety, and social comparison related to their digital interactions, others discovered solace in mindfulness apps and maintained positive social connections. These results underscore the need for comprehensive digital literacy programs to empower students with the skills to navigate the emotional landscape of the digital age adeptly. Furthermore, the research highlights the pivotal roles of parents and educators in guiding responsible smartphone use. Parents are instrumental in setting boundaries, fostering healthy technology habits, and promoting a harmonious equilibrium between virtual and real-world experiences. Educators, on the other hand, can harness the potential of smartphones for educational enrichment, leveraging interactive learning and digital resources to enhance students' academic journeys. In conclusion, this research elucidates the intricate relationship between smartphone use and students' motor skills and emotional well-being. Recognizing the dual nature of technology's impact, it emphasizes the importance of conscientious engagement with smartphones to maximize their advantages while mitigating potential risks. As we navigate the digital era, the insights from this study contribute to informed discussions, enabling educators, parents, and policymakers to craft strategies that harness the potential of smartphones as tools for empowerment and enrichment in the lives of students.
Nikel Partiküller ile Takviye Edilmiş Magnezyum Matrisli Kompozitlerin Üretimi ve Karakterizasyonu
Authors: KELEN Fevzi
Published: October 2023

Metal matrisli kompozit malzemeler otomotiv endüstrisinde yaygın olarak kullanılmaktadır. Düşük

ağırlığın son derece önemli olduğu bu alanda magnezyum esaslıların tüketim hacimleri her geçen gün

artmaktadır. Fakat oda sıcaklığında gözlenen düşük süneklilikleri ve yetersiz dayanımları hem otomotiv

sektöründe hem de endüstride demir, çelik ve alüminyuma göre kullanımlarını önemli oranda

kısıtlamaktadır. Mevcut çalışmada, hacimce %0-%10 oranlarında, mükemmel süneklilik, iyi tokluk ve

yüksek elastik modül gibi üstün özelliklere sahip nikel mikro partiküller ile takviye edilmiş magnezyum

matrisli kompozit malzemeler toz metalürjisi yöntemlerinden tek eksenli sıcak presleme tekniği ile imal

edilmiştir. Üretim parametrelerinin optimizasyonu sonucu tüm numunelerde yaklaşık olarak tam

yoğunluğa ulaşılmış ve gözenek içermedikleri tespit edilmiştir. Mikroyapısal incelemelerde α (Mg) ve Ni

fazlarına ilaveten Mg2Ni fazı da gözlenmiştir. Bu bileşik, ayrıca, XRD analizlerinde de belirlenmiştir.

Güçlendirici ilavesi ile matris malzemesinin oda sıcaklığı akma ve basma dayanımlarında sırasıyla %37

ve %35 oranlarında iyileşmeler elde edilmiş ve tüm test sıcaklıklarında saf magnezyuma göre daha

yüksek değerlere sahip olduğu görülmüştür. Kompozit malzemeler gerek mekanik özellikleri gerekse de

düşük yoğunlukları ile otomotiv ve endüstride kullanılan geleneksel malzemelere önemli bir alternatif

teşkil ettiği saptanmıştır.
Derinkuyu Yeraltı Şehrinin Sabit Saçıcılı İnterferometri Tekniği İle İncelenmesi
Authors: OKTAR Osman
Published: October 2023

Bu çalışmada, Derinkuyu Yeraltı Şehrinin bulunduğu bölgede uydu bakış doğrultusundaki (LOS) hareketlerin belirlenmesi amacıyla Derinkuyu merkezini kapsayacak şekilde PSInSAR analizi gerçekleştirilmiştir. PSInSAR analizinde 11.10.2014 İle 09.12.2022 tarihleri arasında algılanmış 37 adet SAR görüntüsü kullanılmıştır. PSInSAR analizi StaMPS programı kullanılarak gerçekleştirilmiştir. Çalışma alanında 2014-2021 (8 yıl), 2018-2021 (4 yıl) ve 2020-2021 (2 yıl) yıllarını kapsayan SAR görüntüleri analiz edilmiştir. Çalışma bölgesi için elde edilen uydu bakış doğrultusundaki (LOS) hızlar incelendiğinde; bölgede yıllık 6.11 mm’ye kadar alçalma değerleri ve -6.25 mm’ye kadar yükselme değerleri elde edilmiştir. LOS yönünde elde edilen hızlar ve standart sapmaları incelendiğinde; Derinkuyu Yeraltı Şehri’nin bulunduğu bölgede anlamlı bir alçalma ve yükselme değerinin bulunmadığı belirlenmiştir.
Cortinarius hinnuleus (Basidiomycota): Türkiye Mikotası İçin Yeni Bir Kayıt
Authors: SESLİ Ertuğrul
Published: October 2023

Cortinarius hinnuleus türüne ait früktifikasyonlar 2022 Yılı’nın Ekim ayında Trabzon İli Maçka İlçesi

Mataracı Mahallesi’nde saptandı. Öncelikli olarak fotoğrafları çekildi, şapka ve sapa ait önemli

morfolojik özellikler not edildi, birkaç tanesi standart yöntemle toplanarak laboratuvara getirildi ve

nihayet kurutularak fungaryuma yerleştirildi. Mikroskobik incelemeler için kuru materyal kullanıldı,

bazidiyosporları görüntülemek için şapkadan bir parça kesildi, %5’lik amonyak çözeltisi içerisinde birkaç

dakika tutuldu ve lamel üzerinde pens yardımı ile sıkıldı. Diğer hücresel yapıları inceleme sırasında ince

kesitler alındı, araştırma mikroskobu ile görüntüleme sağlandı ve mikroskobik fotoğraflar çekildi.

Çalışmalar sonucunda türün Türkiye için yeni kayıt olduğu sonucuna varıldı. Kanıtlayıcı materyal Trabzon

Üniversitesi’nde saklanmaktadır.
Domateste Tuz Stresi İle Mücadelede Potansiyel Bir Organik Madde Olan Kitosanın Rolü
Authors: BULUT Hüseyin , ÖZTÜRK Halil İbrahim
Published: October 2023

Domates yetiştiriciliğinde verim kayıplarına neden olan kritik faktörlerden birisi toprak tuzluluğudur.

Tuzluluğun neden olduğu stres ile mücadele son zamanlarda küresel bir konu haline gelmiştir. Kitosanın

abiyotik streslerin bitkiler üzerinde neden olduğu zararlı etkilerini azaltmada rolü olduğu bilinmektedir.

Toksik olmayan, biyolojik olarak uyumlu, biyolojik olarak parçalanabilen ve organik bir takviye olarak

kullanılan kitosan, tarımsal üretimde son yıllarda büyük ilgi görmektedir. Bu çalışmada, tuz stresi

altındaki domates fidelerinde kitosanın morfolojik büyüme parametrelerine etkisi ve çekirdek hasarını

iyileştirmedeki rolü incelenmiştir. Domates fidelerinde tuz hasarının boyutu ve kitosanın buna karşı

etkisi morfolojik parametreler ve Comet assay ile DNA hasarı değerlendirilmiştir. Tuz stresinin fideler

üzerindeki morfolojik etkisi bitki boyu, gövde yüksekliği, gövde çapı, yaprak alanı ve yaprak sapı

uzunluğu verilerinden elde edilmiştir. Stres etkisiyle oluşan DNA hasar düzeyi, DNA hasarının göstergesi

olarak kabul edilen kuyruk uzunluğu, kuyruk DNA % değeri ve kuyruk momenti ile belirlenmiştir.

Uygulanan kitosanın domates fidelerinin morfolojik özellikleri üzerinde olumlu etkisi olduğu

saptanmıştır. Kitosan takviyesinin bazı dozlarda DNA hasarını azaltmada etkili olmuştur. Çalışma

sonuçlarımız uygulanan tuzun domates fidelerinde doz miktarına bağlı olarak strese neden olduğunu ve

kitosanın domates fidelerini tuz stresinin yıkıcı etkilerinden korumak için etkin bir şekilde

kullanılabileceğini ortaya koymuştur.
Etiopatogenia del hipertiroidismo
Authors:   , Gómez Raúl Manuel
Published: October 2023

El hipertiroidismo, según Marañón, es la hiperfunción de la glándula tiroidea, dando origen a un síndrome muy conocido, caracterizado por la irritabilidad del sistema neuro vegetativo y del sistema Nervioso Central, y por típicos trastornos metabólicos, entre los que descuella el aumento del Metabolismo basal. De las manifestaciones resultantes las más típicas son: la taquicardia, el temblor, la retracción del elevador del párpado, el adelgazamiento, la inquietud psíquica y motora. El hipertiroidismo aparece unas veces sin causa conocida, pero en la mayoría de los casos obedece a uno de estos tres motivos: emociones, infecciones y accidentes de la vida sexual.
Estudio de la distribución estadística de aberraciones cromosómicas inducidas por radiación
Authors:   , Benítez José Desiderio
Published: October 2023

Atwood y Wolff mostraron que la distribución de Poisson no ajusta a los valores del cuadro 1 para aberraciones por múltiples rupturas de cromosomas. En este trabajo se muestra que tampoco otras distribuciones conocidas ajustan a esos valores, por lo que se decidió obtener la distribución específica correspondiente al fenómeno de aberraciones por múltiples rupturas inducidas por radiación. Para eso se encuentra que es conveniente considerar este fenómeno como un proceso que se desarrolla con el tiempo; en base a las características conocidas del fenómeno se puede proponer para describirlo el modelo de proceso estocástico de Markov de nacimiento puro, del cual el proceso y la distribución de Poisson son casos particulares. Este modelo propuesto permite obtener la distribución estadística específica del fenómeno. La distribución obtenida con este modelo permite predecir que, aumentando el tiempo de irradiación, el número de células con una aberración será mayor que el número de células con ninguna aberración. Si continúa aumentando el tiempo de irradiación, el número de células con dos aberraciones puede ser mayor que el número de células con otra cantidad de aberraciones, Pero la mayor probabilidad de tener dos aberraciones en un instante t2 es mucho menor que la probabilidad máxima de tener una aberración en un instante anterior t1; o sea, aunque se prolongue el tiempo de irradiación, disminuye la probabilidad que las células lleguen a tener dos o más aberraciones, hasta, que se igualan tendiendo a cero todas las probabilidades de obtener células con cualquier número de aberraciones. Esta conclusión es compatible con la propiedad de las constantes λx , de constituir una sucesión monótona decreciente hasta anularse rápidamente.
Contribución al estudio del contenido de histamina en extractos varios de glándulas: su estimación y su eliminación por histaminasa
Authors:   , Tabak Moisés
Published: October 2023

La finalidad que nos ha llevado a realizar este trabajo, ha sido el hecho de que la histamina, una sustancia química del grupo de las aminas biógenas, que si bien se caracteriza por tener ciertas acciones farmacodinámicas bien manifiestas, tales como la disminución de la presión sanguínea, el aumento del tono bronquiolar, el aumento de la secreción gástrica, etc., presenta sin embargo el inconveniente de tener otras acciones secundarias desfavorables y que por tal motivo hacen que su utilización en terapéutica requiera ciertas precauciones. Está contenida la histamina en la mayor parte de los órganos tales como el intestino, los pulmones, el riñon, el hígado y también en la piel. A raíz de ello, se ha observado que ciertos extractos glandulares preparados con fines terapéuticos presentaban el inconveniente de que al ser administrados, daban origen a ciertos fenómenos característicos tales les como urticaria u otras manifestaciones semejantes a los que producía la histamina. Por lo tanto, la finalidad de nuestro trabajo ha sido verificar en primer lugar si dichos extractos contenían histamina, en que cantidad y concomitantamente encontrar un método de poder eliminarla de los productos en que se la encuentra, sin que por ello se modifiquen o alteren la composición y propiedades originales de los extractos mencionados.
Особливості формування гомогенізованих зображень плоско-фокусуючими лінзами Френеля
Authors: Петров В. В. , Антонов Є. Є. , Зенін В. М. , Манько Д. Ю. , Шанойло С. М.
Published: October 2023

Розроблено алгоритм моделювання мікропризмових концентраторних лінз Френеля, які формують у фокальній площині гомогенне зображення пройдених світлових променів. Такі плоско-фокусуючі лінзи дозволяють формувати оптимальний сигнал у системах автоматичного керування рухомими об’єктами з чотирьохплощинними фотодетекторами, а також є перспективними для використання в сонячних фотоелектричних модулях. За допомогою колімованого лазерного променя експериментально досліджено деякі зразки спеціалізованих трансформуючих мікропризмових структур, які виготовлено методом алмаз-ного мікроточіння за результатами моделювання і формують у фокусі рівномірне освітлення світлової плями у формі світлового кола та кола з кільцем. Методом комп’ютерного моделювання знайдено профілі пройдених світлових променів, що дозволило виявити причини додаткового розширення заломлених потоків світла.
Розділення джерел даних і вилучення цільових компонентів електрофізіологічних часових рядів на прикладі ЕКГ плода
Authors: Білобородова Т. О. , Скарга-Бандурова І. С.
Published: October 2023

Електрофізіологічні часові ряди є ціннім джерелом інформації, але, час-тіше за все, представлені миттєвими невідомими лінійними сумішами джерел. У цьому випадку постає задача виділення джерела необхідної інформації, відкидаючи інші, щоб виявити компоненти даних, що є актуальним завданням при виділенні електрокардіограми (ЕКГ) плода з електрофізіологічних даних абдомінальної електрокардіограми матері. Запропонована послідовність обробки електрофізіологічних даних скла-дається з чотирьох етапів: попередньої обробки даних, декореляції даних на основі аналізу основних компонент, застосуванні алгоритму розділення джерела з метою виділення цільових даних, скасуванні нецільових даних за допомогою узагальненого розкладання власних значень і аналізу періодичних компонентів. Практичну реалізацію послідовності обробки даних для виділення ЕКГ плода проведено із використанням запису, який включає записи п’яти абдомінальних каналів та одного грудного відведення, що відповідає ЕКГ жінки. Результат середньоквадратичної помилки та співвідношення сигнал/шум показує, що представлений підхід придатний для виділення серцебиття плода та подальшого аналізу ЕКГ плода з даних абдомінальних каналів.
Розробка та дослідження модифікованої згорткової нейронної мережи для розпізнавання образів малярійних клітин
Authors: Федорченко Є. М. , Олійник А. О. , Степаненко О.О. , Федорончак Т. В. , Чорнобук М. О.
Published: October 2023

Проведено огляд та аналіз відомих рішень для проблеми виявлення малярії за знімками крові пацієнтів з використанням алгоритмів машинного навчання. Після розробки моделі машинного навчання для вирішення поставленої задачі на основі згорткових нейронних мереж проведене тестування точності роботи моделі та її порівняння з розглянутими аналогами. За результатами тестування було встановлено, що за показником точності класифікації модель знаходиться на рівні найкращих розглянутих моделей, маючи точність класифікації 98,08 %.
Estimating the Effects of HIV/AIDS on Orphanhood and School Enrolment in Sub-Saharan Africa
Authors: Ozegbe Roseline O. , Babatunde M. Adetunji
Published: October 2023

This study examined the impact of AIDS on the prevalence of orphanhood, and its implications for human capital development in sub-Saharan Africa (SSA) between 2000 and 2004, using data from various demographic and health surveys. It was found that there was a significant negative relationship between school enrolment and being an AIDS orphan, irrespective of gender consideration. In addition, empirical evidence suggests that paternal AIDS orphans suffer more deprivation than other groups of orphans.
Urban Development and Environmental Implications: The challenge of urban sustainability in Nigeria
Authors: Olorunfemi F.B. , Raheem U.A.
Published: October 2023

The impact of rapid urbanization has indeed become a major threat to the quality of urban environment, human health and urban productivity in Nigeria. It is therefore not surprising that the living environments in most cities in Nigeria are ‘life and health threatening’. Today’s urban environment in Nigeria is at best described as unsustainable. This situation poses a serious challenge to urban administrators, planners, other professionals as well as urban residents in the country. Poorly managed urban growth as obtained in Nigeria creates irreversible environmental and natural resources degradation with a concomitant increase in poverty. Urban environmental problems are exacerbated because policies do not account for environmental factors. In resolving the environmental implications of rapid urbanization in Nigeria, as articulated in this paper, there is need to apply sound principles of environmental management through the integration of environmental planning into development.
Impact Assessment of HIV/AIDS Knowledge and Prevention among Patrons of Bars and Hotels in Abuja, Nigeria
Authors: Aderinto Adeyinka A. , Erinosho Layi , Nwokocha Ezebunwa E. , Adesanmi Olufunke A.
Published: October 2023

The Federal Capital Territory (FCT) Abuja, is notable for its increasing population and convergence of peoples and cultures. This high volume of in-migration into the FCT exerts a considerable pressure on the economic and social life of its inhabitants. Understandably, bar/hotel business rat*s among the most patronized ventures in the city as a result of multiple government, academic/research and nongovemment engagements and attendant activities of sex workers who visit such bars and hotels. As a result of the number of people that have stake either as proprietors or patrons and the centrality of these business outfits to the understanding of events in the city, selected bars and hotels were chosen for this impact study on HIV/AlDS-knowledge and prevention. The main objective of this study is to assess the impact of various HIV/AIDS intervention programmes on the knowledge and attitudes of patrons of bars and hotels in the FCT towards HIV/AIDS and adoption of preventive methods through exposure to different prevention strategies. Data for this study were collected at two levels through: (1) a preintervention baseline survey; and (2) post-intervention questionnaires. In this way, the level of the effects of the AlDS-education progratnme on respondents’ knowledge and attitude to HIV/AIDS prevention measures was highlighted. The findings show clearly that multiple socioeconomic and cultural factors influence patronage of bars and hotels in the FCT; and the intervention impacted positively on respondents’ knowledge of HN/AIDS, as well as condom use
Group Differences in the Resolve to Mentor of Potential Mentors
Authors: Okurame David E.
Published: October 2023

This study examines the resolve to mentor of individuals with no mentors, with male mentors, and with female mentors, using a sample of 70 male and 70 female potential mentors in the Nigerian work environment. Descriptive statistics showed that the greatest level of resolve to mentor was made by respondents in the female mentor group, followed by those in the male mentor group; the least was by respondents in the no mentor group. Results of one way analysis of variance revealed a significant difference in resolve to mentor of respondents in these groups. The source of the significant difference was the low resolve to mentor in the no mentor group compared to the high level recorded in the female mentor category. Generally, male respondents in each of the study groups reported a higher level of resolve to mentor than their female counterparts. These findings are discussed in the context of mentoring and goal commitment literature. The study represents the first enquiry of a potential mentor’s resolve to mentor. The practical implication of findings is that individuals will be more resolute to serve as mentors if organizations create a pleasant mentoring experience for them by training their mentors, especially male mentors, in the act of effective delivery of mentoring. Findings further suggest that better incentive to serve as mentors is possible through a reward policy and a training package to improve perceptions of mentor benefits, especially among female potential mentors who were less resolute to mentor.
AUTISMO INFANTIL: IMPACTO DO DIAGNÓSTICO E REPERCUSSÕES NA SAÚDE MENTAL DOS PAIS*
Authors: Alves Francisca Laura Ferreira de Sousa , Paz Glenda Amurim Maciel
Published: October 2023

Introdução: A aceitação do diagnóstico do TEA é complexo para a família, considerado queesse transtorno ainda é desconhecido, gerando nos pais sentimentos como medo, tristeza,frustração. Objetivos: Identificar o impacto do diagnóstico do Transtorno do Espectro Autistana saúde mental dos pais. Metodologia:Tratasse de estudo descritivo, qualitativo, quantitativoe transversal por meio do Google Forms. No período de junho a agosto de 2023, com os pais.A coleta foi realizada mediante dois questionários autorais de 10 e 9 questões, no qual foianalisado o conhecimento acerca do Espectro Autista e o impacto do diagnóstico na saúdemental dos pais.Resultados: Em relação ao questionário aplicado quando indagados sobre osentimento ao receber o diagnóstico, 0% (0) raiva,41,67% (5) tristeza, 8,33% (1) culpa, 0%(0) negação, 41,67% (5) frustração e 25% (3) todos, os pais poderiam escolher mais umaopção para marcar.Foi indagado aos pais se tinham a cabeça cheia de preocupações 58,33%(7) relatam que sim, 8,33% (1) não e 33,33% e (4) às vezes, quando questionados sepercebem uma maior facilidade em ficarem estressados 50% (6) afirmaram que sim, 8,33%(1), não e 41,67% (5) às vezes,foi interrogado aos pais se costumam chorar com frequência50% (6) relataram que sim, 25% (3) não, 25% (3) às vezes. Conclusão: Foi possívelevidenciar que o diagnóstico do Transtorno do Espectro Autista impacta a saúde mental dospais, especialmente a das mães que assumem a maior parte das obrigações na criação ecuidado dos filhos.
Explicaciones Causales en Adolescentes Bilingües de Escuela Pública de Ayacucho
Authors: Lam Luis , Frisancho Susana
Published: October 2023

La presente investigación explora el desarrollo de las explicaciones causales de un grupo de adolescentes bilingües de Ayacucho, Perú, en relación a diversas tareas relacionadas a la causalidad en fenómenos físicos (ascenso del nivel del agua y flotación). Se compara este desarrollo con el desarrollo operatorio (i.e. la conservación de la sustancia y peso), con el fin de explorar la articulación del desarrollo de la causalidad y el de las operaciones. Se parte del marco conceptual de la teoría de Jean Piaget y de su método “clínico-crítico” para evaluar las explicaciones de los adolescentes. Los resultados corroboran los hallazgos de los trabajos originales de Piaget y colaboradores y sirven de apoyo a la validez de la teoría Piagetiana en otros contextos socioculturales.
Pode o pessoal ser mais que político? Resistências ao reconhecimento da cientificidade do feminismo e reflexões à luz da teoria dos campos de Pierre Bourdieu
Authors: PORTO Ana Carla Vaz , CAVALCANTE Cláudia Valente
Published: October 2023

O presente artigo, confeccionado por meio de pesquisa bibliográfica, objetiva, por meio de uma leitura historicizada, analisar as resistências ao reconhecimento da cientificidade do feminismo por parcela das feministas e dos acadêmicos brasileiros à luz da teoria dos campos do sociólogo francês Pierre Bourdieu. Para que se compreenda melhor o tema central, desenvolve-se inicialmente uma narrativa sucinta acerca do histórico do feminismo e seu percurso pelos campos social, político e científico. Como resultado do diálogo estabelecido com a teoria de Bourdieu, tem-se que são naturais as resistências ao reconhecimento da cientificidade do feminismo nos campos feminista e acadêmico brasileiros, pois os agentes que integram tais campos estão em disputa permanente por posições privilegiadas e a negação ou inferiorização do novo e do distinto figuram como estratégias, ainda que inconscientes, para manutenção da dominância. A despeito de tais resistências, é inegável o acúmulo de atributos científicos para a legitimação acadêmica do feminismo no Brasil, o que corrobora a ênfase de Bourdieu no fato de que os campos não são estáticos, estando em constante mutação.
EDUKASI PENINGKATAN KESADARAN REMAJA MENGENAI DAMPAK DARI PENGGUNAAN MEDIA SOSIAL DI SMAN 1 SUSUT
Authors: Udariani Arnesia , Putri Dewa Ayu Putu Adhiya Garini , Budiarnaya Putu
Published: October 2023

Saat ini di Indonesia media sosial semakin banyak digunakan, dengan persentase 75,50% dari keseluruhan total pengguna media sosial di Indonesia menjadikan kalangan remaja menempati posisi yang tinggi. Bali menjadi salah satu provinsi yang padat penduduk dan juga media sosial menjadi penghubung antara individu yang satu dengan lainnya secara lebih mudah khususnya daerah Bangli. Namun, dari sekian banyak dampak positif yang diberikan, tentu ada dampak negatifnya. Penyalahgunaan media sosial menjadikan media sosial memiliki citra yang negatif di kalangan masyarakat, seperti penerimaan informasi yang salah hingga kecanduan dalam menggunakan media sosial. Sehingga sangat diperlukan pengetahuan tambahan untuk mampu menggunakan media sosial secara baik dan bijak sesuai dengan harapan awal. Metode yang digunakan adalah dengan observasi lokasi untuk analisis masalah yang menjadi isu di masyarakat, menyiapkan kajian literatur lalu pemberian edukasi dan dilanjutkan dengan evaluasi pemahaman. Pemberian edukasi yang diwakilkan oleh siswa di SMA Negeri 1 Susut, dengan materi bijak dalam menggunakan media sosial. Tujuan dari kegiatan pengabdian masyarakat untuk memberikan kesadaran akan dampak yang diberikan oleh media sosial dan diperkuat oleh hasil evaluasi pemahaman siswa yang cukup baik setelah pemberian edukasi diharapkan siswa mampu lebih kritis dalam menerima informasi, juga mampu memberikan edukasi lebih lanjut kepada masyarakat luas khususnya di daerah Desa Sulahan
ASESMEN KOMPETENSI KARYAWAN BANK PERKREDITAN RAKYAT KABUPATEN ROKAN HULU, PROVINSI RIAU
Authors: Tavip Junaedi Achmad , Sudarno Sudarno , Suhardjo Suhardjo , Wijaya Evelyn , Ng Martha
Published: October 2023

Karyawan merupakan bagian penting dalam suatu organisasi yang mampu menggerakkan dan mensinergikan sumber daya lainnya untuk mencapai tujuan organisasi. Keberhasilan organisasi sangat ditentukan oleh peran dan fungsi karyawan yang ada di dalamnya. Oleh karena itu, organisasi harus memberdayakan semua komponen karyawan yang dimiliki dengan baik agar mampu meningkatkan kinerja dengan melakukan proses penilaian kompetensi karyawan berdasarkan fungsi dan jabatan yang dituju. Kegiatan asesmen kompetensi bagi karyawan Bank Perkreditan Rakyat Rokan Hulu dilaksanakan pada tanggal 16-17 Juli 2022 dengan jumlah peserta sebanyak 32 orang. Kegiatan PKM ini bertujuan untuk melakukan penilaian kompetensi karyawan berdasarkan fungsi dan jabatan yang dituju. Penilaian kompetensi karyawan akan dilakukan terhadap calon pegawai, pegawai tetap, kepala seksi, dan kepala cabang berdasar pada aspek psikologis dan aspek kompetensi manajerial. Hasil kegiatan memperlihatkan bahwa terdapat 23 peserta berada pada kategori Masih Memenuhi Syarat (MMS), 5 peserta berada pada kategori Memenuhi Syarat (MS) dan 4 peserta berada pada kategori Kurang Memenuhi Syarat (KMS). Dengan demikian secara keseluruhan terdapat 28 peserta yang disarankan untuk promosi pada jabatan yang dituju dan 4 peserta yang tidak disarankan untuk promosi pada jabatan yang dituju.