bluuebunny/crossref_metadata_2025 huggingface dataset:
A Model Development Approach Based on Point Cloud Reconstruction and Mapping Texture Enhancement
Authors: You Boyang , Honarvar Shakibaei Asli Barmak
Published: November 2024

To address the challenge of rapid geometric model development in the digital twin industry, this paper presents a comprehensive pipeline for constructing 3D models from images using monocular vision imaging principles. Firstly, a structure-from-motion (SFM) algorithm generates a 3D point cloud from photographs. The feature detection methods scale-invariant feature transform (SIFT), speeded-up robust features (SURF), and KAZE are compared across six datasets, with SIFT proving the most effective (matching rate higher than 0.12). Using K-nearest-neighbor matching and random sample consensus (RANSAC), refined feature point matching and 3D spatial representation are achieved via antipodal geometry. Then, the Poisson surface reconstruction algorithm converts the point cloud into a mesh model. Additionally, texture images are enhanced by leveraging a visual geometry group (VGG) network-based deep learning approach. Content images from a dataset provide geometric contours via higher-level VGG layers, while textures from style images are extracted using the lower-level layers. These are fused to create texture-transferred images, where the image quality assessment (IQA) metrics SSIM and PSNR are used to evaluate texture-enhanced images. Finally, texture mapping integrates the enhanced textures with the mesh model, improving the scene representation with enhanced texture. The method presented in this paper surpassed a LiDAR-based reconstruction approach by 20% in terms of point cloud density and number of model facets, while the hardware cost was only 1% of that associated with LiDAR.
How Cyber Security Enhances Trust and Commitment to Customer Retention: The Mediating Role of Robotic Service Quality
Authors: Panditharathna Roshan , Liu Yang , de Macedo Bergamo Fabio Vinicius , Appiah Dominic , Trim Peter R. J. , Lee Yang-Im
Published: November 2024

Cyber security is supportive of robotic service provision, the objective of which is to help marketers achieve their aim of providing a high level of service. Marketers need to be aware of cyber security issues and adhere to established cyber security policies. We investigate trust and commitment in relation to customer retention while assessing the mediating role of robotic service quality (RSQ). We employ a survey-based study that utilises 231 valid responses from customers in São Paulo, Brazil. To analyse the data, we used partial least squares structural equation modelling (PLS-SEM). The results show that trust and commitment have a positive impact on customer retention. RSQ has a partial mediation effect on the relationship between the latent constructs of trust, commitment, and customer retention. Thus, it can be suggested that RSQ, which embeds trust and commitment, assists in building a loyal customer base. Marketers outside the Latin American region can benefit from the results of this study since it incorporates cyber security awareness and policy within marketing strategy implementation, ensuring that RSQ is aligned in terms of the digitalisation goals of the company.
Analysis of Umbilical Artery Hemodynamics in Development of Intrauterine Growth Restriction Using Computational Fluid Dynamics with Doppler Ultrasound
Authors: Song Xue , Wang Jingying , Sun Ke , Lee Chunhian
Published: November 2024

Intrauterine growth restriction (IUGR), the failure of the fetus to achieve his/her growth potential, is a common and complex problem in pregnancy. Clinically, IUGR is usually monitored using Doppler ultrasound of the umbilical artery (UA). The Doppler waveform is generally divided into three typical patterns in IUGR development, from normal blood flow (Normal), to the loss of end diastolic blood flow (LDBF), and even to the reversal of end diastolic blood flow (RDBF). Unfortunately, Doppler ultrasound hardly provides complete UA hemodynamics in detail, while the present in silico computational fluid dynamics (CFD) can provide this with the necessary ultrasound information. In this paper, CFD is employed to simulate the periodic UA blood flow for three typical states of IUGR, which shows comprehensive information on blood flow velocity, pressure, and wall shear stress (WSS). A new finding is the “hysteresis effect” between the UA blood flow velocity and pressure drop in which the former always changes after the latter by 0.1–0.2 times a cardiac cycle due to the unsteady flow. The degree of hysteresis is a promising indicator characterizing the evolution of IUGR. CFD successfully shows the hemodynamic details in different development situations of IUGR, and undoubtedly, its results would also help clinicians to further understand the relationship between the UA blood flow status and fetal growth restriction.
AI-Driven Prediction of Symptom Trajectories in Cancer Care: A Deep Learning Approach for Chemotherapy Management
Authors: Finkelstein Joseph , Smiley Aref , Echeverria Christina , Mooney Kathi
Published: November 2024

This study presents an advanced method for predicting symptom escalation in chemotherapy patients using Long Short-Term Memory (LSTM) networks and Convolutional Neural Networks (CNNs). The accurate prediction of symptom escalation is critical in cancer care to enable timely interventions and improve symptom management to enhance patients’ quality of life during treatment. The analytical dataset consists of daily self-reported symptom logs from chemotherapy patients, including a wide range of symptoms, such as nausea, fatigue, and pain. The original dataset was highly imbalanced, with approximately 84% of the data containing no symptom escalation. The data were resampled into varying interval lengths to address this imbalance and improve the model’s ability to detect symptom escalation (n = 3 to n = 7 days). This allowed the model to predict significant changes in symptom severity across these intervals. The results indicate that shorter intervals (n = 3 days) yielded the highest overall performance, with the CNN model achieving an accuracy of 81%, precision of 87%, recall of 80%, and an F1 score of 83%. This was an improvement over the LSTM model, which had an accuracy of 79%, precision of 85%, recall of 79%, and an F1 score of 82%. The model’s accuracy and recall declined as the interval length increased, though precision remained relatively stable. The findings demonstrate that both CNN’s temporospatial feature extraction and LSTM’s temporal modeling effectively capture escalation patterns in symptom progression. By integrating these predictive models into digital health systems, healthcare providers can offer more personalized and proactive care, enabling earlier interventions that may reduce symptom burden and improve treatment adherence. Ultimately, this approach has the potential to significantly enhance the overall quality of life for chemotherapy patients by providing real-time insights into symptom trajectories and guiding clinical decision making.
Metabolites and Metabolic Functional Changes—Potential Markers for Endothelial Cell Senescence
Authors: Ya Jingyuan , Whitby Alison , Bayraktutan Ulvi
Published: November 2024

Accumulation of senescent endothelial cells (ECs) in vasculature represents a key step in the development of vascular aging and ensuing age-related diseases. Given that removal of senescent ECs may prevent disease and improve health and wellbeing, the discovery of novel biomarkers that effectively identify senescent cells is of particular importance. As crucial elements for biological pathways and reliable bioindicators of cellular processes, metabolites demand attention in this context. Using senescent human brain microvascular endothelial cells (HBMECs) displaying a secretory phenotype and significant morphological, nuclear, and enzymatic changes compared to their young counterparts, this study has shown that senescent HBMECs lose their endothelial characteristics as evidenced by the disappearance of CD31/PECAM-1 from interendothelial cell junctions. The metabolic profiling of young versus senescent HBMECs also indicates significant differences in glucose, glutamine, and fatty acid metabolism. The analysis of intracellular and secreted metabolites proposes L-proline, L-glutamate, NAD+, and taurine/hypotaurine pathway components as potential biomarkers. However, further studies are required to assess the value of these agents as potential biomarkers and therapeutic targets.
Augmented Reality and Computational Simulations for the Preprocedural Planning of Transcatheter Aortic Valve Replacement After Previous Transcatheter Mitral Valve Replacement
Authors: Scuoppo Roberta , Catalano Chiara , Costagliola Eleonora , Cannata Stefano , Pasta Salvatore , Gandolfo Caterina
Published: November 2024

Transcatheter aortic valve replacement (TAVR) has become the preferred treatment for patients with aortic stenosis (AS) at high surgical risk. However, TAVR is challenging in patients with a pre-existing mitral valve prosthesis, such as a transcatheter mitral valve replacement (TMVR), due to the likelihood of device interference. This study explores the feasibility and safety of performing TAVR in a patient with a pre-existing TMVR procedure using 3D printing, augmented reality (AR) and computational simulations to optimize preprocedural planning. Computational modeling allowed predictions of the spatial relationship between the TAVR and TMVR devices. The simulation output was therefore used as input for augmented visualization of the device interference. The 3D printing of an anatomical replica was used to physically simulate the procedure, ensuring that no significant interference would occur during heart function. The results demonstrated a safe distance of 6.4 mm between the TAVR and TMVR devices, and no functional interference was observed during simulated cardiac cycles. The use of AR in the operating room enhanced the understanding of device positioning, offering a new dimension of precision of the complex cardiovascular intervention. This study concludes that integrating AR, 3D printing, and computational simulations into preprocedural planning for high-risk structural intervention can significantly improve procedural outcomes by enhancing accuracy, safety, and operator confidence.
Update on the Biological and Clinical Relevance of Mast Cells in Chronic Rhinosinusitis with Nasal Polyps
Authors: Locatello Luca Giovanni , Tonon Silvia , Mele Vincenzo , Santini Simone , Miani Cesare , Pucillo Carlo Ennio Michele
Published: November 2024

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common inflammatory disorder whose complex immunopathogenesis has yet to be fully elucidated. Endotype-2 CRSwNP is the most common form of disease where eosinophils are the main drivers of inflammation. Traditional treatments for CRSwNP have centered around intranasal or systemic corticosteroids and endoscopic sinus surgery (ESS). However, recent advancements in targeted therapies have introduced novel biological agents that specifically target key inflammatory mediators such as IL-4, IL-5, and IL-13. These biologics offer promising options for patients with CRSwNP, particularly those who do not respond adequately to conventional treatments. Nonetheless, some patients do not satisfactorily respond to these drugs because of an insufficient blockade of the inflammatory process. The mast cell (MC) is another important (and somehow neglected) actor in the pathogenesis of CRSwNP, and the latest clinical and translational evidence in this field has been reviewed in the present paper.
Integrating Historical Learning and Multi-View Attention with Hierarchical Feature Fusion for Robotic Manipulation
Authors: Lu Gaoxiong , Yan Zeyu , Luo Jianing , Li Wei
Published: November 2024

Humans typically make decisions based on past experiences and observations, while in the field of robotic manipulation, the robot’s action prediction often relies solely on current observations, which tends to make robots overlook environmental changes or become ineffective when current observations are suboptimal. To address this pivotal challenge in robotics, inspired by human cognitive processes, we propose our method which integrates historical learning and multi-view attention to improve the performance of robotic manipulation. Based on a spatio-temporal attention mechanism, our method not only combines observations from current and past steps but also integrates historical actions to better perceive changes in robots’ behaviours and their impacts on the environment. We also employ a mutual information-based multi-view attention module to automatically focus on valuable perspectives, thereby incorporating more effective information for decision-making. Furthermore, inspired by human visual system which processes both global context and local texture details, we have devised a method that merges semantic and texture features, aiding robots in understanding the task and enhancing their capability to handle fine-grained tasks. Extensive experiments in RLBench and real-world scenarios demonstrate that our method effectively handles various tasks and exhibits notable robustness and adaptability.
Neurofeedback Technology Reduces Cortisol Levels in Bruxismitle Patients: Assessment of Cerebral Activity and Anxiolytic Effects of Origanum majorana Essential Oil
Authors: Merino José Joaquín , Parmigiani-Izquierdo José María , Gasca Adolfo Toledano , Cabaña-Muñoz María Eugenia
Published: November 2024

Cerebral activities were measured during 21 essions in NeurOptimal (NO)-trained patients with bruxism. Salivary cortisol levels were quantified for each six training sessions (session 1, 6, 12, 18, 21) in 12 patients with bruxism after performing their pre- and post-NeurOptimal sessions. Their cortisol levels were compared with controls (without stress). We evaluated whether NO overtraining could reduce stress in bruxism after 21 repeated sessions with/without Origanum majorana inhalation by using nasal impregned filters with this essential oil (n = 12). This study enrolled 89 participants (590 salivary samples for cortisol assessment by ELISA ng/mL). Salivary samples were collected at several NO learning sessions (session 1, 6, 12, 18, and 21). In the present study, we assessed whether Origanum majorana essential oil exposure during 21 NO training sessions can promote anxiolytic effects by reducing cortisol levels in Bruxismitle patients or modulate their brain activities. The experimental design also included control subjects without NO training (n = 30) and unstressed participants without bruxism, as well as trained NeurOptimal (n = 5) participants during the 21 sessions, also including control subjects without stress. In our study, NeurOptimal post-training decreased cortisol levels in Bruxismitle patients, reducing stress scores on the Hamilton II scale after 21 NO sessions; finally, Origanum majorana essential oil exposure during NO training could enhance anxiolytic effects of repeated NO in Bruxismitle patients. The parameter divergence as an index of cerebral activity evaluates the reached difference between cerebral activity at pre-learning (PRE) minus post-training (POST) values in Bruxismitle participants with/without Origanum majorana odor exposure during each NO training sessions. As a consequence of NO overtraining, these cerebral activities fluctuate reaching a calm state while anxious states are associated with high divergences. The reduction in divergences when they are close to zero by habituation means a final calm state is reached by NO overtraining, while higher divergences mean anxiogenic states. Collectively, Origanum majorana essential oil inhalation during NO training could decrease salivary cortisol levels after 21 NO training sessions in Bruxismitle.
Peroxidase-like Nanoparticles of Noble Metals Stimulate Increasing Sensitivity of Flavocytochrome b2-Based L-Lactate Biosensors
Authors: Gayda Galina , Demkiv Olha , Stasyuk Nataliya , Boretsky Yuriy , Gonchar Mykhailo , Nisnevitch Marina
Published: November 2024

We report the development of amperometric biosensors (ABSs) employing flavocytochrome b2 (Fcb2) coupled with nanoparticles (NPs) of noble metals on graphite electrode (GE) surfaces. Each NPs/GE configuration was evaluated for its ability to decompose hydrogen peroxide (H2O2), mimicking peroxidase (PO) activity. The most effective nanoPO (nPO) was selected for developing ABSs targeting L-lactate. Consequently, several Fcb2/nPO-based ABSs with enhanced sensitivity to L-lactate were developed, demonstrating mediated ET between Fcb2 and the GE surface. The positive effect of noble metal NPs on Fcb2-based sensor sensitivity may be explained by the synergy between their dual roles as both PO mimetics and electron transfer mediators. Furthermore, our findings provide preliminary data that may prompt a re-evaluation of the mechanism of L-lactate oxidation in Fcb2-mediated catalysis. Previously, it was believed that L-lactate oxidation via Fcb2 catalysis did not produce H2O2, unlike catalysis via L-lactate oxidase. Our initial research revealed that the inclusion of nPO in Fcb2-based ABSs significantly increased their sensitivity. Employing other PO mimetics in ABSs for L-lactate yielded similar results, reinforcing our hypothesis that trace amounts of H2O2 may be generated as a transient intermediate in this reaction. The presence of nPO enhances the L-lactate oxidation rate through H2O2 utilization, leading to signal amplification and heightened bioelectrode sensitivity. The proposed ABSs have been successfully tested on blood serum and fermented food samples, showing their promise for L-lactate monitoring in medicine and the food industry.
Polyneuropathy in Cerebrotendinous Xanthomatosis: Diagnostic Challenges and Potential for Therapeutic Intervention
Authors: Camelo-Filho Antonio Edvan , Lima Pedro Lucas Grangeiro Sá Barreto , Cavalcante Francisco Luciano Honório Barreto , Miyajima Oliver Reiks , Santos Carolina Figueiredo , da Rosa Rodrigo Fagundes , Pessoa André Luiz Santos , Braga-Neto Pedro , Nóbrega Paulo Ribeiro
Published: November 2024

Cerebrotendinous xanthomatosis (CTX) is a rare metabolic disorder caused by mutations in the CYP27A1 gene, leading to cholestanol accumulation in various tissues, including peripheral nerves. Polyneuropathy is an underrecognized feature with considerable variability in clinical presentation and neurophysiological findings in CTX. This review assesses the prevalence, clinical manifestations, and diagnostic methodologies of polyneuropathy in CTX, exploring its underlying mechanisms and potential treatment outcomes. A literature review was conducted using PubMed, Embase, and the Virtual Health Library databases with search terms related to CTX and polyneuropathy. A total of 892 articles were initially identified, with 59 selected for in-depth analysis. The review focused on studies examining peripheral nerve involvement in CTX, including nerve conduction studies, electromyography, and nerve ultrasound. Polyneuropathy in CTX was observed in 50% to 77.7% of patients across multiple case series. Neurophysiological findings varied, with reports of axonal, demyelinating, and mixed polyneuropathies. Clinical presentation included lower limb atrophy, pes cavus, and distal weakness, with sensory symptoms less frequently reported. Treatment with chenodeoxycholic acid (CDCA) showed potential in improving nerve conduction parameters, although the response was variable and dependent on the timing of intervention. Polyneuropathy in CTX presents significant diagnostic challenges due to its heterogeneous presentation and varying neurophysiological findings. Early recognition and intervention are crucial for improving patient outcomes. Peripheral nerve ultrasound is a promising diagnostic tool, complementing traditional neurophysiological assessments. Further research is needed to standardize protocols and explore the full therapeutic potential of CDCA in managing CTX-related polyneuropathy.
A Critical Review of the Technical Characteristics of Recycled Brick Powder and Its Influence on Concrete Properties
Authors: Hu Jinkang , Ahmed Wisal , Jiao Dengwu
Published: November 2024

This paper presents a systematic overview of the applications of RBP as a substitute for cement. Initially, the fundamental properties of RBP, including physical properties, chemical compositions, and morphology, are discussed. Subsequently, the effects of RBP on various aspects of cement-based materials, such as fresh properties, shrinkage behavior, hydration, microstructure, strength development, and durability, are thoroughly reviewed. The findings of this study reveal that waste brick powder exhibits pozzolanic activity and can be used to partially replace cement in concrete formulations. However, its relatively high water absorption and irregular shape increase the water demand and, thus, reduce the rheological properties. The incorporation of RBP with 10–20% or finer particle sizes can refine the pore structure and promote the formation of hydration products. However, replacements of RBP greater than 25% can lead to adverse effects on the mechanical properties, frost resistance, and carbonation resistance of cementitious composites. Therefore, to enhance the effectiveness of RBP, measures such as improving fineness, incorporating mineral admixtures, adjusting curing conditions, and applying nano- or chemical modifications are necessary. This study provides valuable technical support for promoting the sustainable preparation of construction materials, which holds important environmental and economic implications.
Novel Cement-Based Materials Using Seawater, Reused Construction Waste, and Alkali Agents
Authors: Bai Yang , Wang Yajun , Yang Tao , Chen Xiaoyang
Published: November 2024

This study aimed to develop marine alkali paste (MAP) produced using seawater (SW), recyclable particle material from paste specimens (RPPs), and alkali agents including NaOH (NH) and Na2O·3SiO2 (NS). The physicochemical properties and strength of the MAP were investigated with uniaxial compression tests (UCTs), an Energy-Dispersive Spectrometer (EDS), X-ray diffraction (XRD), and thermal-field emission scanning electron microscopy (SEM). The key information on the MAP preparation and experiments, including mix ratios, ages, curing, and sub-specimen locations, were recorded during the investigation. The results indicated that 8-day-old MAP prepared with NS reached a maximum compressive strength of 8.3 MPa, while 8-day-old NH-prepared specimens achieved up to 5.59 MPa. By 49 days, NS-prepared MAP had strengths between 5.46 MPa and 7.34 MPa, while the strength of NH-prepared MAP ranged from 3.59 MPa to 5.83 MPa. The key hydration products were Friedel’s salt (3CaO·Al2O3·CaCl2·10H2O, FS), xCaO·SiO2·nH2O (C-S-H), CaO·Al2O3·2SiO2·4H2O (C-A-S-H), and Na2O·Al2O3·zSiO2·2H2O (N-A-S-H). C-S-H was generated under the critical curing and working conditions in SW. C-A-S-H development contributed to C-S-H network compaction. N-A-S-H development helped in resistance to SO42− erosion, thereby cutting down ettringite (Ca6Al2(SO4)3(OH)12·26H2O) development. The active ion exchange between MAP and SW mainly involving SO42− and Cl− led to the significant formation of FS at the interface of C-A-S-H and xCaO·Al2O3·nH2O (C-A-H). Therefore, FS generation inhibited SO42− and Cl− corrosion in the MAP and rebounded the interface cracks of the hydration products. Consequently, FS contributed to the protection and development of C-S-H in the MAP, which ensured the suitability and applicability of the MAP in marine environments.
Addition of a Perfluoroalkyl Acetyl Group to the C-Vertex of a Carborane Anion to Enhance Its Solubility in Fluorinated Ether Solvents
Authors: Iwashita Sota , Kimura Mutsumi , Kitazawa Yu
Published: November 2024

The modification of carborane anion monocarba-closo-dodecaborate (1) with perfluoroalkyl groups enhances its solubility in fluorinated ethers. This novel approach achieves a degree of solubility that is unattainable by using traditional lipophilic modifications or boro–vertex functionalizations of 1. A spectroscopic analysis in combination with DFT calculations confirmed that these new anions retain their weakly coordinating nature and exhibit moderate chemical stability.
Cleavage Reaction Lateral Flow Assays for Salivary Pepsin Measurement Using a Pepsin-Susceptible Peptide Substrate
Authors: Kang Sung-Woong , Lee Young Ju , Lee Jae-Chul , Eun Young-Gyu , Lee Gi-Ja
Published: November 2024

In this study, we introduce a novel cleavage reaction lateral flow assay (LFA) based on pepsin activity against a pepsin-susceptible peptide (PSP) substrate to detect salivary pepsin. Two types of cleavage reaction LFAs, the within-tube and on-strip cleavage reactions, were prepared based on the PSP and pepsin reaction location. In the within-tube cleavage reaction LFA, samples were treated in the microtube within a heating block for 30 min separately and subsequently developed with running buffer in the LFA. For the on-strip cleavage reaction, samples were treated on the reaction zone of the strip within the heating zone of the multifunctional strip cassette for 10 min. After developing the running buffer in the LFA, the assay image was obtained using a universal mobile reader with a multifunctional strip cassette. The within-tube cleavage reaction LFA showed high sensitivity (limit of detection [LOD] 1.9 ng/mL), good specificity, and high reproducibility. This assay exhibited better linearity in the log concentration range of pepsin (4–500 ng/mL) than a commercially available dipstick assay. The on-strip cleavage reaction LFA showed a similar sensitivity (LOD 1.4 ng/mL) to that of the within-tube reaction assay. Therefore, we expect these cleavage reaction LFAs using PSP to be utilized as simple and effective tools to detect salivary pepsin.
Correction: Asonitou, K.; Koutsouki, D. PASS Theory and Movement Disorders: Methodology for Assessment and Intervention. Children 2024, 11, 1192
Authors: Asonitou Katerina , Koutsouki Dimitra
Published: November 2024

In the original publication [...]
Affective Touch in Preterm Infant Development: Neurobiological Mechanisms and Implications for Child–Caregiver Attachment and Neonatal Care
Authors: La Rosa Valentina Lucia , Geraci Alessandra , Iacono Alice , Commodari Elena
Published: November 2024

Background/Objectives: Affective touch is crucial in infant development, particularly in regulating emotional, cognitive, and physiological processes. Preterm infants are often deprived of essential tactile stimulation owing to their early exposure to the external environment, which may affect long-term developmental outcomes. This review aimed to examine the neurobiological mechanisms of affective touch and highlight effective interventions, such as skin-to-skin contact (SSC) and kangaroo care (KC), to promote development in preterm infants. Methods: This review summarizes recent studies in the literature on affective touch, the role of C-tactile fibers, and the effects of tactile interventions in neonatal care. Studies were selected based on their relevance to the care and development of preterm infants, with a focus on physiological and neurodevelopmental outcomes. Key interventions, including SSC and massage therapy, are discussed in relation to their effectiveness in the neonatal intensive care unit (NICU). Results: The results suggest that affective touch, mainly through activation of tactile C-fibers, improves caregiver–infant bonding, reduces stress responses, and supports neurodevelopment in preterm infants. Interventions such as SSC and KC have also been shown to improve physiological regulation in these infants, including heart rate, breathing, and temperature control while promoting emotional regulation and cognitive development. Conclusions: Affective touch is a key component of early development, particularly in preterm infants admitted to the NICU. Integrating tactile interventions such as SSC and KC into neonatal care practices may significantly improve long-term developmental outcomes. Future research should explore the epigenetic mechanisms underlying affective touch and further refine tactile interventions to optimize neonatal care.
Factors Influencing Rural Women’s Adoption of Climate Change Adaptation Strategies: Evidence from the Chivi District of Zimbabwe
Authors: Belle Johanes , Mapingure Tendai , Owolabi Solomon Temidayo
Published: November 2024

The socio-cultural leadership system in rural communities of developing countries is generally gender-biased, thus rendering female-headed households (FHHs) vulnerable to climate change risk. This study explored the factors influencing FHHs’ adoption of a climate change adaptation strategy (CCAS) in Chivi District, Zimbabwe. We used a multistage sampling technique and logistic regression to evaluate 107 women household heads’ livelihood and their decision to adopt the CCAS in Ward 25 of the Chivi District. The results show that the age of the female head significantly influenced the CCAS decision (R2 = −0.073), along with marital status (R2 = 0.110), agricultural training (R2 = 0.133), club membership (R2 = 0.084), and farm size (R2 = 0.014). Access to formal agricultural training plays a prominent role. At the same time, the institutional framework showed variations and laxity on the part of the local government, as access to extension services varies significantly. In addition, education level was reported to have an insignificant (p = 0.098) influence on CCAS adoption. Overall, multiple institutional and socio-economic factors are essential in influencing CCAS decisions. Hence, central and local governments are encouraged to improve outreach strategies on deploying supporting tools, extension agents, and vital stakeholders for strategic information dissemination to sensitize rural dwellers and community leaders on women’s and FHHs’ crucial role in food security and their resilience to climate change risk. Moreover, the educational syllabus can be enhanced at all rural education levels to reshape the norms of future generations against the customary impact of old age on farming approaches and to encourage women’s participation in decision making and interventions, particularly those sensitive to their societal contributions.
Environmental Representation on Australian Children’s Television: An Analysis of Conservation Messages and Nature Portrayals
Authors: Morgan Breanna L. , Smith Bradley P.
Published: November 2024

The early connection children form with nature is vital in fostering positive attitudes towards the environment. Television plays a significant role in shaping these attitudes, yet the inclusion of environmental messaging in children’s programs remains unexplored. This study investigates the extent of conservation messages and nature portrayals on Australian free-to-air children’s television. A mixed-methods approach was employed, analysing all programs airing on ABC Kids, a network aimed at children aged two to six years old, over a seven-day period. Phase 1 involved summarising program descriptions, types, styles, moral themes, and durations. Phase 2 entailed viewing all episodes and noting environmental representations, which were then analysed using content analysis. Only 14.3% of programs (10/70), representing 10.3% of airtime (481/4652 min), included an ‘Environmental Experiences’ moral theme. Content analysis revealed six distinct themes in environmental representations, with more positive than negative messages. These messages were predominantly implicit, conveyed through character dialogue and imagery. Environmental moments represented a balance of flora and fauna but were largely not fact-based. This study suggests a need for increased airtime for environmentally focused programs and more consideration of current environmental issues. Producers are encouraged to include more positive environmental morals and align themes with children’s learning styles to enhance their connection to and understanding of environmental issues.
The Potential Applications of Natural Colostrum in Skin Health
Authors: Bolat Ecem , Karagöz Zeynep , Alves José Luiz de Brito , Neto José Patrocínio Ribeiro Cruz , Witkowska Anna Maria , El-Seedi Hesham , Lombardo Mauro , Karav Sercan
Published: November 2024

Skin is a crucial organ for preserving the body’s equilibrium. Like other parts of the body, skin also ages due to extrinsic and intrinsic factors, leading to several signs such as wrinkles, spots, and a decline in elasticity, causing a range of issues similar to those seen elsewhere in the body. Some of these factors include ultraviolet (UV) radiation, hormonal disorders, genetic factors, loss of moisture, metabolic disorders, exposure to chemicals, and smoking. Colostrum, which is the initial foremilk, has shown positive effects on the consequences of these factors. Its content is richer than mature milk and contains several beneficial components. For instance, it includes hyaluronic acid, a molecule that binds water and keeps the skin hydrated; lactoferrin, with high antimicrobial properties; immunoglobulins, which are responsible for immunity; growth factors, which increase the amount of collagen, the main protein type of the skin; and, finally, the telomerase enzyme, which maintains the telomere’s length and, thus, decelerates the aging process. It has recently become apparent that using skin products with natural ingredients is essential. Considering its nature, contents, and effects, colostrum stands out as an excellent material for the cosmetic industry, especially for the aging sector. Therefore, the aim of this review article is to demonstrate the potential application of natural colostrum in skin health and its usage in natural cosmetic products in the cosmetic sector.
Performance and Characterization of Additively Manufactured BST Varactor Enhanced by Photonic Thermal Processing
Authors: Molina Carlos , Guneroglu Ugur , Zaman Adnan , Li Liguan , Wang Jing
Published: November 2024

The demand for reconfigurable devices for emerging RF and microwave applications has been growing in recent years, with additive manufacturing and photonic thermal treatment presenting new possibilities to supplement conventional fabrication processes to meet this demand. In this paper, we present the realization and analysis of barium–strontium–titanate-(Ba0.5Sr0.5TiO3)-based ferroelectric variable capacitors (varactors), which are additively deposited on top of conventionally fabricated interdigitated capacitors and enhanced by photonic thermal processing. The ferroelectric solution with suspended BST nanoparticles is deposited on the device using an ambient spray pyrolysis method and is sintered at low temperatures using photonic thermal processing by leveraging the high surface-to-volume ratio of the BST nanoparticles. The deposited film is qualitatively characterized using SEM imaging and XRD measurements, while the varactor devices are quantitatively characterized by using high-frequency RF measurements from 300 MHz to 10 GHz under an applied DC bias voltage ranging from 0 V to 50 V. We observe a maximum tunability of 60.6% at 1 GHz under an applied electric field of 25 kV/mm (25 V/μm). These results show promise for the implementation of photonic thermal processing and additive manufacturing as a means to integrate reconfigurable ferroelectric varactors in flexible electronics or tightly packaged on-chip applications, where a limited thermal budget hinders the conventional thermal processing.
Lattice Dynamics of Ni3-xCoxB2O6 Solid Solutions
Authors: Sofronova Svetlana N. , Pavlovskii Maksim S. , Krylova Svetlana N. , Vtyurin Alexander N. , Krylov Alexander S.
Published: November 2024

On the one hand, Ni3-xCoxB2O6 solid solutions are promising anode materials for lithium batteries, and on the other hand, they have antiferromagnetic properties. This study examines the lattice dynamics of Ni3-xCoxB2O6 solid solutions for x = 0, 1, 2, 3 by means of quantum chemistry and Raman spectroscopy. The vibrational spectra of the compound NiCo2B2O6 have been studied using the polarized Raman spectroscopy method. Good agreement was found between the theoretical and experimental results. As expected, the largest change in frequencies was observed in the modes where the vibrations of the metal ion had a large amplitude. The substitution of cobalt by nickel does not lead to the appearance of soft modes. This fact indicates that the structures of the solid solutions are stable.
Cr3+ Doping Effects on Structural, Optical, and Morphological Characteristics of BaTiO3 Nanoparticles and Their Bioactive Behavior
Authors: Mamani Flores Efracio , Vera Barrios Bertha Silvana , Huillca Huillca Julio César , Chacaltana García Jesús Alfredo , Polo Bravo Carlos Armando , Nina Mendoza Henry Edgardo , Quispe Cohaila Alberto Bacilio , Gamarra Gómez Francisco , Tamayo Calderón Rocío María , Fora Quispe Gabriela de Lourdes , Sacari Sacari Elisban Juani
Published: November 2024

This study investigates the effects of chromium (Cr3+) doping on BaTiO3 nanoparticles synthesized via the sol–gel route. X-ray diffraction confirms a Cr-induced cubic-to-tetragonal phase transition, with lattice parameters and crystallite size varying systematically with Cr3+ content. UV–visible spectroscopy reveals a monotonic decrease in bandgap energy from 3.168 eV (pure BaTiO3) to 2.604 eV (5% Cr3+-doped BaTiO3). Raman and FTIR spectroscopy elucidate structural distortions and vibrational mode alterations caused by Cr3+ incorporation. Transmission electron microscopy and energy-dispersive X-ray spectroscopy verify nanoscale morphology and successful Cr3+ doping (up to 1.64 atom%). Antioxidant activity, evaluated using the DPPH assay, shows stable radical scavenging for pure BaTiO3 (40.70–43.33%), with decreased activity at higher Cr3+ doping levels. Antibacterial efficacy against Escherichia coli peaks at 0.5% Cr3+ doping (10.569 mm inhibition zone at 1.5 mg/mL), decreasing at higher concentrations. This study demonstrates the tunability of structural, optical, and bioactive properties in Cr3+-doped BaTiO3 nanoparticles, highlighting their potential as multifunctional materials for electronics, photocatalysis, and biomedical applications.
Enhancing Wireless Power Transfer Performance Based on a Digital Honeycomb Metamaterial Structure for Multiple Charging Locations
Authors: Huu Nguyen Bui , Thanh Son Pham , Hiep Le Thi Hong , Anh Nguyen Hai , Tung Do Khanh , Khuyen Bui Xuan , Tung Bui Son , Lam Vu Dinh , Zheng Haiyu , Chen Liangyao , Lee YoungPak
Published: November 2024

Enhancing the efficiency is an essential target of the wireless power transfer (WPT) technology. Enabling the WPT systems requires careful control to prevent power from being transferred to unintended areas. This is essential in improving the efficiency and minimizing the flux leakage that might otherwise occur. Selective field localization can effectively reduce the flux leakage from the WPT systems. In this work, we propose a method using a digital honeycomb metamaterial structure that has a property operation as a function of switching between 0 and 1 states. These cavities were created by strongly confining the field by using a hybridization bandgap that arose from wave interaction with a two-dimensional array of local resonators on the metasurface. A WPT efficiency of 64% at 13.56 MHz was achieved by using the metamaterial and improved to 60% compared to the system without the metamaterial with an area ratio of Rx:Tx~1:28. Rx is the receiver coil, and Tx is the transmitter one.
Advances in Green Nanocomposites: Design, Characterization and Applications
Authors: Viscusi Gianluca
Published: November 2024

Nowadays, green nanocomposites are gaining interest in different application fields [...]
‘George’s Gymnastics Program’, a Community Gymnastic Program for Children with a Disability: Perceptions of Participant Stakeholders
Authors: Brusco Natasha K. , Henderson Jane , Merison Clare , Saber Kelly , Woon Anita , Whittaker Sara L. , Lunniss Nikki , McAleer Rachael , McMillan Maddy , Wilson Amy-Claire , Peries Isuru , Correia Jade , Zhou Alyssa , Zeler Brittany , Soultanidis Reka , O′Keefe Samantha , Lake Tara , Trinh Hysha , Gin Madeleine , Luo Darren , Patussi Jessica , Xu Lulu , Wright Rebecca , Layton Natasha
Published: November 2024

Background: The aim of this study is to understand what children with a disability like and dislike about participating in a gymnastics program, and to understand the views of the adults supporting the program. Methods: Children with a mild intellectual disability (aged 5–12) from a primary school providing special education participated in one of four gymnastics programs (1 h/week for 5 weeks) at a gymnastics centre. The program included ~25–50 children per group, with ~20 adults providing support, including gymnastics coaches, teachers, and adult students on placement. To evaluate the program, children (11–12-year-olds; n = 51) were invited to complete a written two-page reflection, and the adults were invited to participate in one of three focus groups. Results: 150 children attended one of four programs. Twenty-six 11–12-year-olds participated in the evaluation (n = 26/51, 51%), and, from the written responses, the themes of ‘individual preference’ and ‘resilience’ emerged. It was found that 96% (n = 25/26) reported they would like to do more gymnastics, 88% (n = 23/26) reported positive feelings during gymnastics, and 65% (n = 17/26) expressed concerns such as feeling tired or hot. Twenty-three adults participated in a focus group. Key themes included the positive impact the program delivery had on the children’s participation; and the positive impact on coaches, students, and teacher’s disability attitudes and knowledge. Conclusions: This gymnastics program was well-liked by children with a disability. To optimise participation, promoting individual choice and control may be of benefit.
A Protocol for Basketball as Inclusive Sport to Boost Motor and Social Skills in Autistic Preschoolers
Authors: Levante Annalisa , Martis Chiara , Antonioli Giuseppe , Dima Massimo , Duma Luigia , Perrone Marco , Lecciso Flavia
Published: November 2024

This paper presents the Early Basketball Protocol, a sports-based intervention designed to improve motor and socio-emotional skills in autistic preschoolers. Recognizing the paucity of sports protocols for younger autistic children, we developed this protocol using basketball rules to foster an inclusive setting where autistic preschoolers (n = 4) and their typically developing peers (n = 13) could engage in activities together. The protocol aims to simultaneously develop motor and socio-emotional skills through inclusive sports activities. Due to the COVID-19 pandemic, the effectiveness of the protocol was evaluated using parent-reported measures. A narrative approach synthesized the parental answers, and a pre–post-test analysis evaluated the preliminary application of the EB protocol based on parent-reported perceptions. Encouraging longitudinal results emerged, particularly in the improvement of socio-emotional skills for all participants. However, the early disruption of activities due to the pandemic may have contributed to the lack of improvement in gross motor skills. The paper discusses the practical implications of these findings and outlines future research directions, emphasizing the critical role of social inclusion.
Coronary Plaque Regression and Fractional Flow Reserve Improvement in a Chronic Coronary Syndrome Case: Early Optimal Medical Therapy and Fractional Flow Reserve-Computed Tomography Follow-Up Strategy
Authors: Yoshimitsu Yuki , Awaya Toru , Kawagoe Naoyuki , Kunimasa Taeko , Iijima Raisuke , Hara Hidehiko
Published: November 2024

Background: Optimal medical therapy (OMT) is increasingly recognized as a cornerstone in managing chronic coronary syndrome (CCS), offering a non-invasive alternative to percutaneous coronary intervention (PCI). Case Presentation: A 38-year-old male with diabetes, dyslipidemia, and hypertension was treated with early and comprehensive OMT, including statins, ezetimibe, sodium-glucose cotransporter 2 inhibitors (SGLT2i), pioglitazone, and renin-angiotensin system inhibitors. Insulin was introduced during the acute phase to stabilize glycemic control. His HbA1c decreased to 6.3% within 4 months. Results: Over 8 months, the patient experienced a reduction in coronary plaque burden and an improvement in fractional flow reserve (FFR) from 0.75 to 0.90, indicating enhanced coronary blood flow. Plaque volume burden decreased from 85% to 52% in key coronary segments. Conclusions: This case highlights the effectiveness of OMT, including statins, ezetimibe, SGLT2i, and pioglitazone, in achieving outcomes comparable to PCI. FFR-computed tomography follow-up is critical in guiding treatment decisions. Continued OMT is recommended if plaque stabilization is observed. If no improvement is observed, OMT should be intensified, and PCI considered as appropriate.
Efficiency of IL-6 in Early Prognosis and Follow-Up in Critically Ill Patients with Septic Shock
Authors: Gamarra-Morales Yenifer , Molina-López Jorge , Santiago-Ruiz Felipe-Carlos , Herrera-Quintana Lourdes , Vázquez-Lorente Héctor , Gascón-Luna Félix , Planells Elena
Published: November 2024

Background/Objectives: The aim of this study was to investigate the response of interleukin-6 (IL-6) during the first few hours of a patient’s stay in the Intensive Care Unit (ICU) in a sample of critically ill patients with septic shock, compared to healthy subjects as controls. Additionally, the study examined the association of IL-6 with morbidity and mortality in these patients, as well as its relationship with biomarkers such as lactic acid, C-reactive protein (CRP) and procalcitonin (PCT). Methods: This was a prospective analytical study involving 28 critically ill patients with septic shock, monitored from ICU admission through to their first three days of stay. Demographic data, comorbidities and clinical information, including IL-6 and severity scores, were recorded. Results: IL-6 levels were significantly higher in patients with septic shock compared to healthy subjects (p < 0.001) upon admission. IL-6 levels decreased by the third day of ICU stay (p < 0.005). An association between IL-6 and mortality was observed (areas under the curve 0.826, confidence interval (CI) 95% 0.659−0.994, p < 0.008). Significant correlations between IL-6 and lactic acid (p < 0.009 and p < 0.018) and partial thromboplastin time (p < 0.004 and p < 0.007) were found on the first and third days, respectively. IL-6 was also the correlated with an anion gap at admission to the ICU (p < 0.009). Conclusions: In conclusion, this study suggests that IL-6 could be a valuable marker for early sepsis follow-up in ICU patients, particularly during the first 72 h of hospitalization, providing important prognostic information in patients with septic shock.
DNA as a Double-Coding Device for Information Conversion and Organization of a Self-Referential Unity
Authors: Muskhelishvili Georgi , Nasser William , Reverchon Sylvie , Travers Andrew
Published: November 2024

Living systems are capable on the one hand of eliciting a coordinated response to changing environments (also known as adaptation), and on the other hand, they are capable of reproducing themselves. Notably, adaptation to environmental change requires the monitoring of the surroundings, while reproduction requires monitoring oneself. These two tasks appear separate and make use of different sources of information. Yet, both the process of adaptation as well as that of reproduction are inextricably coupled to alterations in genomic DNA expression, while a cell behaves as an indivisible unity in which apparently independent processes and mechanisms are both integrated and coordinated. We argue that at the most basic level, this integration is enabled by the unique property of the DNA to act as a double coding device harboring two logically distinct types of information. We review biological systems of different complexities and infer that the inter-conversion of these two distinct types of DNA information represents a fundamental self-referential device underlying both systemic integration and coordinated adaptive responses.