bluuebunny/crossref_metadata_2025 huggingface dataset:
САМОЕ ЗНАЧИМОЕ РОССИЙСКОЕ ИНФОКОММУНИКАЦИОННОЕ СОБЫТИЕ ГОДА
Authors: Набоких Л. , Попов С.
Published: June 2022

С 26 по 29 апреля 2022 года в ЦВК "Экспоцентр" в пятый раз прошла Российская неделя высоких технологий, крупнейший в нашей отрасли ежегодный выставочно-конгрессный проект, объединивший наряду с якорным событием − 34-й Международной выставкой информационных и коммуникационных технологий "Связь-2022" − целый ряд форумов и конференций в сфере телекоммуникаций, ИТ, навигации и телематики. Деловая программа РНВТ включила в себя форум "Связь-2022", форум "Российский софт: эффективные решения", XV Международный навигационный форум, стратегическую сессию "Цифровой суверенитет – приоритеты, кадры, законы", XXVI форум Международной академии связи, ряд других отраслевых мероприятий.
МОНИТОРИНГ СЕТЕВОГО ТРАФИКА В МАГИСТРАЛЬНЫХ СЕТЯХ ДЛЯ ОБЕСПЕЧЕНИЯ РАБОТЫ СЕТЕЙ TSN
Authors: Сторожук М.
Published: June 2022

Рассматривается возможность построения анализатора трафика реального времени на основе программируемой логической интегральной схемы для контроллера программно конфигурируемой сети, который должен обеспечить эффективную работу протокола синхронизации TSN.
АРХИТЕКТУРА СЕТЕЙ 6G: ПРИНЦИПЫ И ОСОБЕННОСТИ ПОСТРОЕНИЯ. ЧАСТЬ 1
Authors: Тихвинский В. , Девяткин Е. , Белявский В. , Смирнов Ю.
Published: June 2022

Статья посвящена анализу принципов и особенностей построения архитектуры сетей шестого поколения (6G) с учетом сформированного на сегодняшний день видения развития и облика сетей мобильной связи международными и национальными проектами сетей 6G, а также Международным союзом электросвязи и государственно-частным партнерским проектом 5GPPP. В первой части статьи представлены принципы построения архитектуры сети 6G, в том числе сквозной сетевой протокол New IP, описывается общая архитектура сети 6G.
Existence of coincidence points for Feng-Liu type multivalued contractions with a singlevalued mapping
Authors: Choudhury Binayak S. , Metiya N. , Kundu S. , Kundu A.
Published: June 2022

In this paper we establish coincidence point results for multivalued Feng-Liu type contractions with a singlevalued mapping. There is a supporting example. Several other existing results are contained in our theorems.
Two-parameter generalization of bihyperbolic Jacobsthal numbers
Authors: Bród Dorota , Szynal-Liana Anetta , Włoch Iwona
Published: June 2022

In this paper, we define a two-parameter generalization of bihyperbolic Jacobsthal numbers. We give Binet formula, the generating functions and some identities for these numbers.
Stability problem in a set of Lebesgue measure zero of bi-additive functional equation
Authors: El Ghali Rachid , Kabbaj Samir
Published: June 2022

Let X be a vector space and Y be a Banach space. Our aim in this paper is to investigate the Hyers-Ulam stability problem of the following bi-additive functional equation f(x + y, s − t) + f(x − y, s + t)=2f(x, s) − 2f(y, t), x, y, s, t ∈ X, where f : X × X → Y . As a consequence, we discuss the stability of the considered functional equation in a restricted domain and in the set of Lebesgue measure zero.
Motivación: metas, expectativas y valores-intereses en relación con el aprendizaje en adolescentes ecuatorianos
Authors: Quintero Cordero Yolvy Javier , Bustillos Peña Mayra Alejandra , Poenitz Ana Victoria , Molina Prendes Norma
Published: June 2022

El artículo tiene como objetivo analizar la motivación desde la concepción de las metas, las expectativas y los valores-intereses que experimentan los adolescentes respecto al proceso de aprendizaje. Los investigadores se apoyaron en los referentes teóricos de Tapia (2005), Rohlfs Domínguez (2016) y Rabino Oliver y Serra Desfilis (2018), entre otros. Es un estudio con enfoque cuantitativo, de tipo descriptivo, con un diseño de campo transeccional. La población está constituida por 540 adolescentes pertenecientes a seis instituciones escolares de la ciudad de Quito, cursantes del octavo, noveno y décimo grado de educación básica superior. Se utilizó como instrumento un cuestionario que fue enviado en línea y respondido por el 75 % de la población, por tanto, la muestra quedó establecida en 405 adolescentes. Este estudio está comprendido dentro de uno de mayor envergadura, el cual está en desarrollo; de manera que, los resultados que emerjan de este serán de carácter preliminar. Una vez aplicado el cuestionario y realizado el análisis correspondiente, se pudo evidenciar que la motivación que mayormente responde hacia el aprendizaje es la relacionada con las expectativas con un 77,5 % (promedio), le sigue valores-intereses con un 61,3 % (promedio) y, en tercer término, la motivación relacionada con metas con un 47,5 %.
Machine Learning with Applications in Breast Cancer Detection
Authors: Kaushik Garvit , Golash Vedant , . Divyanshu , Garg Saksham
Published: June 2022

Abstract: This briefing will give an overview of Machine Learning Techniques (MLT) and their applications. It's used to identify patterns in data, analyze trends and make predictions using algorithms. It evolved from a study in computational theory and pattern recognition to touch industries that range from education to government. It is widely considered a key tool in decisionmaking. We present a review on the most recent ML methods used in modeling cancer progression. We present the latest works using ML techniques to model patient outcomes or cancer risk, in light of the increasing use of ML methods for cancerresearch.
Chest X-Ray Examiner
Authors: Ahmed Md. Toukir , Ali Mohammed Sowket
Published: June 2022

Abstract: The most common image taken in the medical field for diagnosis of any ailment affecting the chest is chest radiography (Chest X-ray). The most common image taken in the medical field for diagnosis of any ailment affecting the chest or neighboring area is chest radiography (Chest X-ray). The use of this approach has been limited due to a scarcity of qualified radiologists. To address this issue, we are developing a computer-aided diagnosis system for chest X-ray disease classification that employs DNN (Deep Neural Network) Transfer learning. CXE (Chest X-Ray Examiner) is a web-based program that works in conjunction with our machine learning console. The most common image taken in the medical field for diagnosis of any ailment affecting the chest is chest radiography (Chest X-ray). There is a Rest API application that serves as a middleman between our user interface and machine learning applications. We used our machine learning console application produced by ML.NET to train our own model using the Mobile.Net v3 Image categorization method. By obtaining X-Ray images from end users, the Chest X-Ray Examiner (CXE) can classify the chest disease name and forecast the accuracy level of that disease. Keywords: Chest X-ray, DNN, API, ML.NET, Chest X-Ray Examiner
A Machine Learning based Healthcare Diagnostic Model
Authors: Mittal Prakhar , Parasher Udit , Khanna Ruhi , Yadav Parv , Kumar Sunil , Khurshid Mariya
Published: June 2022

Abstract: This To live a healthy life, healthcare is considered very important but it is terribly difficult to get consultation from a doctor nowadays. The basic idea and motive of the project is to build a chatbot system by using AI (Artificial Intelligence) that can predict the health problems and give details of the disease before consulting the Doctor. The system provides text assistance to coordinate with the chatbot. Based on user’s symptoms chatbot will provide what kind of disease user have and provide doctor’s details according to the diagnose. Based on the symptom that user have chatbot will tell user the disease with all the other possible symptoms. The chat will inform whether the disease is major or minor. Hence, user can gain the maximum benefit of this AI based chatbot only after it diagnoses maximum kinds of illness and provide with all the required information(Abstract) Keywords: Online Diagnosis, Chatbot, Healthcare, Diseases (key words)
Mitigation of Power System Transients in a Multi- Machine System Using STATCOM
Authors: Patil Vinoda , Nandakumar Prof.
Published: June 2022

Abstract: The tremendous expansion of linked power systems as a result of rising electrical energy consumption has created a slew of problems. FACTS (Flexible Alternating Current Transmission System) controllers become crucial in these situations. This paper investigates the transient stability enhancement of IEEE 9 bus system using STATCOM. The damping power oscillations and power swings and setting time is observed with and without STATCOM. Keywords: PI controller Power, D-Q theory. Reactive and Active Power STACOM
Detecting the Best Route to Destination with Minimum Covid19 Infection Chances
Authors: Aranke Parth
Published: June 2022

Abstract: Hazard of covid 19 is increasing by day-by-day. Many organizations have tried to address this issue in this own way. More than 20,000 articles about covid-19 has been published.[4] Some have tried to track the covid-19 patients while some systems tried to keep a track of occurrences of patients. While travelling in public the next person standing to you, Or the next person standing to you might be infected. Masks and other measures can be used to avoid the spread but as long as we are in the vicinity of other patients the chances of getting infected are very high. There arises the need of a System which will decide an alternative route to the destination, based on the chances of the getting infected by covid-19. The mobile application will generate all the possible routes to the destination and then calculate the density of covid-19 patients across each of them and then it will decide the best route to the destination
Obstacle Avoiding Robot: A Review
Authors: Bharti Amit Kumar , Bharati Arvind Kumar , Raza Asharaf , Kumar Ashwani , . Aamir
Published: June 2022

Abstract: In today’s world Robotics is a fast-growing and very interesting field. The concept of Robotics is now used in every sector whether it is in manufacturing industry, medical, transport etc. Obstacle avoidance is one of the features that is needed for the automated mobile robots. In this there is a robot that consist of Arduino UNO (Microcontroller) and sensor that detect presence of obstacles. Programming is done by the Arduino software. The ultrasonic sensor is highly accurate in detecting obstacles in the surroundings. This is a wheeled robot. Keywords: Obstacle, Robotics, Avoidance, Detection, Wheeled robot.
Online VetMeds System
Authors: Ahmed Shaikh Abuosama Rizwan , Farid Attar Faiz , Rajendra Desale Vaibhav , Gawali Prof. N. V.
Published: June 2022

Abstract: Online VetMeds is web based application. User can post requirement for medicine of their pets. User can purchase medicine online. Medicine delivery provided by the nearest associate pet store. Prescription is mandatory for ordering medicine. As per prescription user can search medicine and useful information to order. This application provides logins to the users. They can maintain their account. The main objective of this medical Booking Store system is to take the whole medical store online so that it is reachable to customers 24/7. Overall online medical booking store will become an efficient, highly responsive and an extremely accurate system. Keywords: pet, medicine, web application
NOCIONES LÓGICO-MATEMÁTICAS EN ALUMNOS CON NECESIDADES EDUCATIVAS ESPECIALES:
Authors: Romero Hernández Andrea , Arnal-Palacián Mónica
Published: June 2022

En este trabajo se realiza una revisión de la evolución de las Necesidades Educativas Especiales y su adaptación en la enseñanza-aprendizaje de las nociones lógico-matemáticas en la etapa de Educación Infantil. Además, se han considerado la manipulación de diferentes materiales y el desarrollo de distintas metodologías para conseguir la inclusión de este alumnado, para llegar a desarrollar una propuesta que aúne a todas estas características. Para ello, se han realizado entrevistas a profesorado.
POR UM DIÁLOGO ENTRE AS CIÊNCIAS HUMANAS, BIOLÓGICAS, MUSICAIS E AS NEUROCIÊNCIAS NO TOCANTE À RELEVÂNCIA DA EDUCAÇÃO MUSICAL PARA A EVOLUÇÃO INFANTIL
Authors: Reinaldo da Silva Gisele , De Farias Costa Carina
Published: June 2022

Este artículo se propone a escudriñar las contribuciones pedagógicas de la educación musical para la formación integral del individuo, con vistas a estimular su aplicabilidad desde la primera infancia. Nos basamos en el diálogo comparativo entre neurociencias, ciencias humanas, biológicas y musicales, a partir de un análisis bibliográfico cualitativo de concepciones teórico-críticas de especialistas en diferentes áreas del conocimiento: Neurociencias, Medicina, Psicología, Fonología, Musicología y Educación. Abordamos los aspectos históricos y culturales inherentes a la educación musical, avanzando para la influencia de estímulos musicales para el desarrollo cerebral, para enfocar, por fin, en las contribuciones cognitivas y socioemocionales oriundas de los estímulos musicales, lo que justifica su relevancia en la experiencia educativa contemporánea, a partir de la mediación docente. Averiguamos que la educación musical actúa en la promoción del aprendizaje significativo y progreso del infante en sentido global.
EL DESAFÍO DE UNA NUEVA SOCIALIZACIÓN DE GÉNERO EN LA EDUCACIÓN INFANTIL
Authors: Contreras Contreras Claudia , Flores Aguilar Paula
Published: June 2022

El presente artículo expone algunas consideraciones sobre los procesos de socialización de género en la infancia, la incidencia que podría generarse desde una aproximación con enfoque de género y cómo el contexto cultural contemporáneo puede influir en el ejercicio de una pedagogía infantil sensible a estos temas. De esta manera, se realiza una discusión teórica a raíz de trabajos que, desde diversas perspectivas, examinan la presencia o abordaje de estereotipos, sesgos y creencias asociadas a lo masculino y lo femenino en el sistema educativo, particularmente bajo la premisa de que ciertas discriminaciones se dan y reproducen en los espacios formativos, privilegiando algunas visiones en las interacciones orientadas a la socialización y aprendizaje infantil.  En tal sentido, se asume que ciertas dinámicas intencionadas desde lo educativo, podrían contribuir a la transformación sociocultural para una socialización de género que promueva nuevas comprensiones relacionales y condiciones de desarrollo equitativas para niñas y niños. A partir de la revisión, se considera que los mayores desafíos en la educación infantil se presentan en aspectos como la necesaria evolución y fortalecimiento integral de los procesos formativos de educadores y educadoras infantiles; el aprovechamiento de las habilidades de las nuevas generaciones en la sociedad de la información, la tecnología y el conocimiento, para posibilitar la socialización de nuevos paradigmas de género y, por último, la promoción de espacios reflexivos y críticos, tendientes a la deconstrucción del modelo machista, especialmente de aquellos vicios y perjuicios que acarrean fenómenos como el currículum oculto y la educación sexista.
UPAYA PENINGKATAN PELAYANAN PERIZINAN MELALUI SISTEM PELAYANAN TERPADU SATU PINTU PADA DINAS PENANAMAN MODAL KOTA JAMBI
Authors: Ayu Tantri Novia , Budhiartie Arrie
Published: June 2022

This paper was written to find out how the one-stop integrated service system at the Jambi City Investment Agency can improve the process of better licensing services. Reform of public service policies, especially in matters of licensing, is an activity that encourages the development of the formal economic sector. Therefore, it is necessary to know how to regulate the one-stop integrated licensing service procedure at the Jambi City One Stop Integrated Investment Service, to know what are the constraints in the implementation of one-stop integrated services at DPMPTSP Jambi City, and how the efforts to increase licensing are carried out at the One Integrated Investment Office Jambi City Door.
FUNGSI BADAN PENGAWAS KEUANGAN DAN PEMBANGUNAN (BPKP) BERDASARKAN PERATURAN PRESIDEN NOMOR 192 TAHUN 2014
Authors: Fitri Irawan Nadia , Syarif Afif
Published: June 2022

Results of the Authority of the Financial and Development Supervisory Agency Based on Presidential Regulation Number 192 of 2014 concerning the Financial and Development Supervisory Agency. Supervision of the planning and implementation of programs and/or activities that may hinder the smooth development, audits of price adjustments, audits of claims, audits of investigations on cases of irregularities indicating financial loss to the state/region, audits of calculating state/regional financial losses, providing expert information and efforts to prevent corruption. Whereas to carry out the supervisory function as stated in Article 3 letter e, in accordance with Article 27 of the Presidential Regulation Number 192 of 2014 it is carried out through the Deputy for Investigation of the BPKP. which reads that the Deputy for Investigation carries out the task of assisting in the field of monitoring the smooth running of development including cross-sectoral programs, prevention of corruption, audits of price adjustments, audits of claims, investigative audits of cases of irregularities with indications of harming state finances, audits of calculating state financial losses and giving expert testimony. Mechanism of the Financial and Development Supervisory Agency (BPKP) Determines State Financial Losses Based on Presidential Regulation Number 192 of 2014 concerning BPKP. The authority of BPKP in laws and regulations is based on the function of BPKP as stated in Article 3 letter e, then BPKP is an institution authorized to calculate (assess) state financial losses, In particular, BPKP is also authorized to assess state financial losses in an effort to prevent corruption because BPKP is also authorized to conduct investigative audits on cases that are indicated to be detrimental to state finances (corruption), When reviewing the source of authority owned by BPKP, then the authority possessed by BPKP is included in the delegative authorit.
Kebijakan Hukum Pemerintah Provinsi Jambi dalam Penyelenggaraan Kesejahteraan Sosial bagi Suku Anak Dalam
Authors: Agusmi Putra Anas , Amir Latifah
Published: June 2022

Penyelenggaraan Kesejahteraan Sosial merupakan bagian kewenangan Pemerintah Daerah jika berdasarkan Asas Desentralisasi. Berbagai macam target penyelenggaraan kesejahteraan sosial berdasarkan Undang-Undang No. 11 Tahun 2009 Tentang Kesejahteraan Sosial, salah satunya adalah Komunitas Adat Terpencil (KAT) dalam hal ini adalah Suku Anak Dalam (SAD) di Provinsi Jambi. Sejauh ini, belum ada suatu kebijakan hukum dari Pemerintah Provinsi Jambi tekait penyelenggaraan Kesejahteraan Sosial bagi SAD sehingga mengakibatkan kesejahteraan sosial bagi mereka belum sepenuhnya terwujud. Oleh karena itu, dalam rangka otonomi daerah dan amanat Pasal 18 ayat (6) UUD 1945, sudah sepatutnya Pemerintah Provinsi Jambi menetapkan sebuah kebijakan yang berpihak kepada SAD sebagai perlindungan hukum bagi mereka terhadap permasalahan sosial yang mereka hadapi. Penelitian ini bertujuan untuk mengetahui serta menganalisis kewenangan dan fungsi Pemerintah Provinsi Jambi dalam Penyelenggaraan Kesejahteraan Sosial bagi Suku Anak Dalam. Penelitian ini adalah penelitian yuridis normatif dengan jenis penelitian deskriptif, menggunakan bahan hukum primer, sekunder dan tersier yang di analisis dengan cara menginterpretasikan, menilai dan mengevaluasi bahan-bahan hukum dengan bersandarkan pada teori-teori hukum yang relevan, untuk kemudian ditarik kesimpulan.
The Effects of COVID-19 outbreak on the Nigerian Stock Exchange performance: Evidence from GARCH Models
Authors: Adenomon Monday Osagie , Maijamaa Bilkisu , John Daniel Owoicholofu
Published: June 2022

The recent COVID-19 was first identified in Wuhan, China in December 2019 and now it has caused huge death and spread to almost all over the world. There are news that most of the world economy and financial markets would be affected due to protocols such as lockdown and social distancing. In Nigeria, the first case of COVID-19 was identified on 27th February 2020 and this present study examines the effect of COVID-19 outbreak on the performance of the Nigeria stock exchange using secondary data for the period of 2nd March 2015 to 16th April, 2020. Also the study considered the COVID-19 period of 2nd January 2020 to 16th April 2020, the results from GARCH models revealed a loss in stock returns and high volatility in stock returns under the COVID-19 period in Nigeria as against the non COVID-19 period. Also, the Quadratic GARCH (QGARCH) and Exponential GARCH (EGARCH) models with dummy variable were applied to the stock returns which shown that the COVID-19 has had negative effect on the stock returns in the Nigeria stock markets. The study therefore recommended that economic policy such as incentive to indigenous companies to create new employments, diversification of the economy to attract new investors, and flexible exchange rate regime that will aid business between Nigeria investors and the international market (trade) be implemented. Lastly, the government of Nigeria should ensure policy that ensures stable political environment and reduction in insecurity in the country.
Properties of a New Generalized Family of Distributions with Application to Relief Times of Patients Data
Authors: Sule Ibrahim , Lawal Hammed Olanrewaju , Bello Olalekan Akanji
Published: June 2022

Statisticians have developed and proposed new families of distributions by extending or generalizing the existing ones. These families of distributions are extended by adding one or more parameters to the baseline distributions to make it more flexible in fitting different kinds of data. In this study, a new four-parameter lifetime family of distributions called the Extended Topp Leone Generalized Exponentiated-G family of distributions was introduced by using the T-X methodology which has been proposed in the literature. Some mathematical properties of the class of distributions such as the moments, moment generating function, quantile function, survival, hazard, reversed hazard and odds functions and Renyi entropy were presented. The estimation of the parameters by maximum likelihood method was discussed. Two sub-models such as extended Topp Leone generalized exponentiated exponential and extended Topp Leone generalized exponentiated Weibull distributions were discussed. An application of extended Topp Leone generalized exponentiated exponential distribution to a real life data set representing the relief times (in minutes) of patients receiving an analgesic was used to show the fit and flexibility of the new distribution over some lifetime distributions in literature. The results showed that the new distribution fits better in this data than the competing models considered.
Knowledge Retention Using “Relay”: A Novel Active-Learning Technique
Authors: Freeman Kathryn , Brown Kathryn , Miller Laura , Nissly Tanner , Ricco Jason , Weinmann Amanda
Published: June 2022

Introduction: Many residency programs utilize passive didactic lectures despite mixed evidence for knowledge retention. This prospective study investigated the efficacy of “relay,” an active-learning technique, as measured by residents' knowledge retention and attitudes compared to traditional format.
Methods: Faculty presented lectures to four family medicine residency programs on a randomized schedule. Lectures were followed by a 15-minute question-and-answer (Q&A) session or relay session. A relay is a collaborative, question-based game. The primary outcome was knowledge retention at 3 months, comparing Q&A to relay sessions as measured by a multiple-choice assessment. Responses were only included if a given resident completed knowledge assessments for both Q&A and relay sessions, to allow for intraresident adjustments, in addition to program, training year, and lecturer/topic. Secondary outcomes included residents' self-perceived knowledge and engagement as surveyed by an ordinal scale immediately following the learning session.
Results: The primary analysis included 51 responses from 18 unique residents. The adjusted mean knowledge assessment score at 3 months was not statistically different after the relay sessions compared to Q&A (67% vs 60%, respectively; 7% difference, 95% CI: -4 to 18%, P=.20). For the secondary outcomes of learner attitudes (n=143 responses), learners reported greater engagement after the relay sessions compared to Q&A (51% vs 28% "very engaged"; overall P=.003), but self-perceived knowledge was not significantly different (overall P=.05, rounded down).
Conclusions: The relay technique did not show significant difference in 3-month knowledge retention, nor immediate self-perceived knowledge, despite greater learner self-perceived engagement.
Acesso à justiça para os invisíveis
Authors: Yuki F. Sorrentino Luciana
Published: June 2022

O presente artigo trata do acesso efetivo à justiça de um grupo socialmente excluído, a população em situação de rua, e os obstáculos que lhe são impostos para o exercício de direitos no Poder Judiciário. E, a partir da identificação dos problemas enfrentados, foi construída a Política Nacional Judicial de Atenção a Pessoas em Situação de Rua, cuja base é a cooperação e a formação de redes interinstitucionais para o pleno atendimento do público a que se dirige. Abordam-se, ainda, os primeiros resultados e aprendizados decorrentes da primeira experiência prática de implementação da política pública no âmbito do Distrito Federal, iniciativa coordenada pelo Tribunal de Justiça do Distrito Federal e dos Territórios - TJDFT.
Concomitant surgical revascularization in post-infarction ventricular septal rupture and ventricular aneurysm repair: a straightforward indication or a prognostic factor?
Authors: Ronco Daniele , Matteucci Matteo , Massimi Giulio , Lorusso Roberto
Published: June 2022

The potential benefit of concomitant surgical revascularization
represents a controversial topic of the surgical treatment of
post-infarction ventricular septal rupture (VSR). Beliaev and colleagues
presented a case series interestingly focusing on this issue and showed
how the possibility to perform coronary artery bypass grafting at time
of VSR repair was associatd with better early and late mortality and
improved cardiac function. However, a few more aspects deserve further
comments in this controversial topic, especially considering late
survival and postoperative cardiac function, although it seems
reasonable to conclude that the presence of coronary artery disease not
amenable to revascularization represents a strong negative prognostic
factor in surgically treated VSR patients.
Fracture of an Orogastric tube in a stroke patient: A case report
Authors: Khanal Surendra , Shrestha Pramesh , Adhikari Aayush , Shrestha Suraj , Kharel Sanjeev , Khadayat Ramesh
Published: June 2022

Orogastric and nasogastric tube are common methods of enteral feeding.
While simple, these methods are not free of complications. A rare
complication of these feeding methods is the fracture of the tube. This
report describes a fracture of an orogastric tube in a 58-year-old
stroke patient.
The chloroplast plays a central role in facilitating MAMP-Triggered Immunity, pathogen suppression of immunity and crosstalk with abiotic stress.
Authors: Breen Susan , Hussain R. Muhammad Fraz , Breeze Emily , Brown Hannah , Alzwiy Ibrahim , Abdelsayed Sara , Gaikwad Trupti , Grant Murray
Published: June 2022

Microbe associated molecular pattern (MAMP) triggered immunity research
has traditionally centred around signal transduction pathways
originating from activated membrane localised pattern recognition
receptors (PRRs), culminating in nuclear transcription and post
translational modifications. More recently, chloroplasts have emerged as
key immune signalling hubs. Chloroplasts play a central role in
integrating environmental signals. Notably MAMP recognition induces
chloroplastic ROS (cROS) which is suppressed by pathogens effectors,
which also modify the balance of defence hormone precursors, jasmonic
acid (JA), salicylic acid (SA) and abscisic acid (ABA), whose precursors
are chloroplast synthesised. This study focuses on how well
characterised PRRs and co-receptors modulate chloroplast physiology,
examining whether diverse signalling pathways converge to similarly
modulate chloroplast function. Pre-treatment of receptor mutant plants
with MAMP and D(Damage)AMP peptides usually protect against effector
modulation of chlorophyll fluorescence and prevent Pseudomonas
syringae effector mediated quenching of cROS and suppression of
F/F. The MAMP-triggered
immunity (MTI) co-receptor double mutant, bak1-5/bkk1-1, exhibits
a remarkable decrease in F/F
compared to control plants during infection, underlining the importance
of MTI mediated signalling in chloroplast immunity. Further probing the
role of the chloroplast in immunity we unexpectedly found that high
light uncouples plant immune signalling.
A pipeline for analysis of allele specific expression from RNA-seq data reveals salinity-dependent response in Nile tilapia
Authors: Campo Aurora , Gershoni Moran , Doron-Faigenboim Adi , Cnaani Avner
Published: June 2022

Species living in a changing environment are capable of adapting to
alterations of various factors. Physiological acclimatization may be
significantly influenced by the heterozygosity, especially with regards
to allele variance and its specific expression (ASE) under different
conditions. Data from RNA-seq experiments can be used to identify and
quantify the alleles expressed, in order to detect and characterize ASE
and regulation of gene expression. However, the allele matching the
reference genome creates a mapping bias that prevents a reliable
estimation of the allele depth unless the haplotype of the experimental
individuals is provided. We developed a pipeline that allows the
identification of the alleles corresponding to an RNA-seq dataset and
their unbiased quantification. This pipeline does not require the
sequencing of the DNA nor the previous knowledge of the haplotype. The
identified SNPs are further substituted in the reference genome, thus
creating two pseudogenomes with the alternative alleles on two
independent samples of the experiment. The SNPs are further called
against each pseudogenome thus providing with two SNP datasets that are
averaged for calculation of the allele depth. The final SNP calling file
contains the coordinates of the SNPs and also the ID of genes containing
the SNPs, the expressed genotypes, the unbiased allele depth and the
statistical tests for identifying ASE according to the experimental
design and correlated with differentially expressed genes. Therefore,
the pipeline presented here can calculate ASE in non-model organisms and
can be applied to previous RNA-seq datasets for expanding studies in
gene expression regulation.
A decreased prevalence of group 2 innate lymphoid cells in blood is associated with good postoperative outcomes in patients with chronic rhinosinusitis
Authors: Tojima Ichiro , Murao Takuya , Kawakita Kento , Nakamura Kengo , Arai Hiroyuki , Matsumoto Koji , Shimizu Shino , Kouzaki Hideaki , Shimizu Takeshi
Published: June 2022

Objectives: The aim of this study was to investigate whether the
prevalence of group 2 innate lymphoid cells (ILC2s) in sinonasal tissues
or in peripheral blood is associated with the postoperative outcome in
chronic rhinosinusitis (CRS) patients. Design: A cross-sectional study
of CRS patients undergoing endoscopic sinus surgery (ESS). Setting: The
Department of Otorhinolaryngology-Head and Neck Surgery at Shiga
University of Medical Science Hospital. Participants: Eleven patients
with eosinophilic CRS (eCRS) and ten patients with non-eCRS were
recruited. Main outcome measures: We examined the ILC2 prevalence in
sinonasal tissues and in peripheral blood before and after ESS.
Lund-Mackay computed tomography (LMK-CT) scores were used to evaluate
the postoperative outcomes; cases with more than 50% improvement were
categorized into the good outcome group, and cases with less than 50%
improvement were categorized into the poor outcome group. Results: The
ILC2 prevalence in sinonasal tissues was correlated with that in
preoperative blood in the eCRS and non-eCRS patients. The ILC2
prevalence in sinonasal tissues and in preoperative blood was not
correlated with the pre- or postoperative LMK-CT scores.
Postoperatively, the ILC2 prevalence in blood was decreased in the eCRS
and non-eCRS patients, and the decrease was associated with the good
outcome group, but not the poor outcome group. Conclusion: The decreased
ILC2 prevalence in blood may be related to good postoperative outcomes
after ESS in eCRS and non-eCRS patients.
Rustrela Virus Infection – A New Emerging Neuropathogen of Red-necked Wallabies ( Macropus rufogriseus)
Authors: Voss Anne , Schlieben Patricia , Gerst Sascha , Langner Christoph , Niesler Michael , Schad Petra , Beer Martin , Rubbenstroth Dennis , Breithaupt Angele , Mundhenk Lars
Published: June 2022

The rustrela virus (RusV) was recently described as a novel pathogen in
a circumscribed area of northern Germany close to the Baltic Sea. Up to
now, the virus has been detected in cases of fatal non-suppurative
meningoencephalitis in zoo animals of different species and a single
wild carnivore as well as in apparently healthy yellow-necked field mice
( Apodemus flavicollis). Data regarding the background of this
previously undiscovered pathogen, including clinical presentation of the
disease, host range, and distribution of the virus, are still limited.
Here, three euthanized red-necked wallabies ( Macropus
rufogriseus) from zoos of different areas in northeastern Germany were
submitted for necropsy after presenting with apathy and therapeutically
unresponsive neurological symptoms. A moderate to severe,
non-suppurative meningoencephalitis was diagnosed in all three cases.
RusV was consistently detected via RT-qPCR and RNA in situ
hybridization in the brains of all wallabies. Other, commonly known
neuropathogens could not be detected. Overall, red-necked wallabies
appear to be highly susceptible to RusV as novel neuropathogen, which is
broader distributed in northeastern Germany.
Predictors of pulmonary involvement in children with COVID-19: How strongly associated is viral load?
Authors: Yakut Nurhayat , Yakut Kahraman , Sarihan Zeynep , Kabasakal Irem , Aydin Murat , Karabulut Nuran
Published: June 2022

This study aimed to investigate epidemiological, clinical, and
laboratory features of children with COVID-19 to identify predictors for
pulmonary involvement. We conducted a retrospective, single-center study
of pediatric COVID-19 at a tertiary care hospital in Turkey between
December 2020 and June 2021. A total of 126 children (70 males, 55.6%)
were examined during the study period. Their mean age was 74.73 ± 81.11
months (range, 1–216 months). The most frequent COVID-19 symptoms were
fever (65.9%), cough (52.4%), and shortness of breath (18.3%). Ten
patients required noninvasive mechanical ventilation. Sixty-nine
patients (54.8%) had pneumonia. Longer duration of fever and the
presence of cough were significantly associated with pulmonary
involvement. In children with pneumonia, the C-reactive protein (CRP),
procalcitonin levels, erythrocyte sedimentation rate (ESR), and viral
load were significantly higher and lymphocyte and thrombocyte counts
were significantly lower than in children without pneumonia. The cutoff
viral load, CRP, and procalcitonin values for predicting pulmonary
involvement were 26.5 cycle threshold (Ct; 95% confidence interval
[CI], 0.54–0.74; sensitivity, 0.65; specificity, 0.56; area under
curve [AUC]: 0.647, p = 0.005), 7.85 mg/L (95% CI,
0.56–0.75; sensitivity, 0.66; specificity, 0.64; AUC = 0.656; p
= 0.003) and 0.105 ng/mL (95% CI, 0.52–0.72; sensitivity, 0.55;
specificity, 0.58; AUC = 0.626; p = 0.02), respectively. High
CRP, procalcitonin levels, ESR, and viral load and low lymphocyte and
thrombocyte counts can predict pulmonary involvement in children with
COVID-19, so better management may be provided for good prognosis.
Association between superoxide dismutase 2, glutathione peroxidase 1, xeroderma pigmentosum group d gene variations, and head and neck squamous cell cancer susceptibility
Authors: Köse Gülçin , Demirbugen Oz , Cömert Ela , Süzen Halit
Published: June 2022

As oxidative stress is implicated in the pathogenesis of head and neck squamous cell cancer (HNSCC), the functions of antioxidant enzyme systems and DNA repair proteins are critical in the development of cancer. To investigate the role of genetic polymorphisms of the antioxidant superoxide dismutase 2 (SOD2) Val16Ala, glutathione peroxidase 1 (GPX1) Pro198Leu, and the DNA repair Xeroderma Pigmentosum Group D (XPD) Lys751Gln genes under exogenous risk factors, including smoking and alcohol consumption, in HNSCC carcinogenesis, we conducted a case-control study on 139 unrelated cases and 265 non-cancer controls. Polymorphisms were analyzed in additive, dominant and recessive genetic models, individually and in an interaction model. Carriers of the T allele of SOD2 were associated with an increased risk for HNSCC in males and smokers; similarly, the T allele of GPX1 was associated with elevated risk in the overall and smoker subgroup. A 12.47-fold increased risk was observed for the carriers of GPX1 TT, SOD2 CT and XPD CC genotypes for HNSCC. This is the first study presenting the potential roles of SOD2, GPX1 and XPD polymorphisms in interaction and under three genetic models in the development of HNSCC. The results suggest that these polymorphisms slightly modify the risk in HNSCC development individually but are significantly higher when they functioned and were evaluated together.
The Use of Third-Party Logistics Services by Large American Manufacturers: The 2004 Survey
Authors: LIEB ROBERT , BENTZ BROOKS A.
Published: June 2022

This article examines the findings of a survey conducted during 2004 of large American manufacturers that addressed their use of third-party logistics (3PL) services. The survey data show that the percentage of those companies using such services is at a record high level, and that users are giving a steadily increasing percentage of their logistics operating budgets to 3PL service providers. Many 3PL relationships are long-term in nature, and the service providers continue to deliver value to their clients. The movement of large American manufacturers into other geographies for sourcing, manufacturing, and sales has led many of their 3PL service providers to expand into those areas to support those activities. During the next several years, the possible adoption of radio frequency identification (RFID) technology by many of these manufacturers will pose significant challenges to their 3PL providers in attempting to meet the related needs of their clients.
Affiliation of Authors in Transportation and Logistics Academic Journals: A Reassessment
Authors: CARTER CRAIG R. , VELLENGA DAVID B. , GENTRY JULIE J. , ALLEN BENJAMIN J.
Published: June 2022

This article updates an ongoing study of author affiliation and institutional productivity based on articles published in peer-reviewed logistics, supply chain management, and transportation journals. Additionally, the authors consider the current status and future trends of journals in electronic format. Our findings show an increasing percentage of contributions by academic as opposed to nonacademic authors. We also find reasonable stability in the publication output of the top ten ranked institutions. However, several new universities, including non-North American schools, have entered the top twenty-five ranked institutions.
Trucking Mergers and Acquisitions in Canada and the U.S. Since NAFTA
Authors: BROOKS MARY R. , RITCHIE PAMELA
Published: June 2022

This article investigates the motivations for a sample of Canadian and U.S. trucking company M&As through a review of press releases picked up by the wire services at the time of announcement, and through an in-depth examination of filings at the time of the M&As. The authors conclude that existing typologies, used to explain M&A activity in other sectors, cannot be usefully applied to the transport sector and so a new typology is proposed. Six case studies are presented to provide support for the proposed typology and, as a secondary issue, to explore the success/failure profile of M&As in the trucking industry.
Influence of Viscosity and Thickener on the Effects of Bleaching Gels
Authors: Torres CRG , Moecke SE , Mafetano APVP , Cornélio LF , Di Nicoló R , Borgesd AB
Published: June 2022

Objective

This study investigated the influence of the viscosity and kind of thickener of 35% hydrogen peroxide bleaching gels on the tooth (color change, demineralization of enamel, and permeation) and on the gel [reactive oxygen species (ROS), pH, and peroxide concentration].

Methods and Materials

Two hundred forty specimens were divided into groups of bleaching gels with different thickeners (CAR, carbomer; ASE, alkali swellable emulsion; MSA, modified sulfonic acid polymer; SSP, semisynthetic polysaccharide; PAC, particulate colloids) in three viscosities (low: 50,000 cP; medium: 250,000 cP; high: 1,000,000 cP). Color change (ΔEab), demineralization of enamel by Knoop microhardness (KHN) reduction analysis, and peroxide permeation (PP) were analyzed in the specimens, while pH, peroxide concentration (PC), and ROS were evaluated in the gels. Data were analyzed by two-way ANOVA (α=0.05).

Results

The higher viscosity gels reduced ΔEab, PP, enamel softening, and ROS in relation to the lower viscosity gels. However, the drop in pH and PC were higher in the more viscous gels. Gels with MSA produced higher ΔEab compared with SSP and ASE. The PP was higher for PAC, and smaller for SSP and CAR. The KHN reduction was higher for CAR and smaller for PAC. The higher pH reduction was seen for ASE and CAR, and the smaller for SSP. The PC reduction was higher for SSP and smaller for CAR. More ROS were observed for MSA and fewer for ASE.

Conclusions

Increased gel viscosity was associated with reduced color change, permeation, demineralization of enamel, and ROS, and led to increased peroxide decomposition and pH alteration during the treatment. The kind of thickener significantly interfered with the treatment effects.
Indole-3-butyric acid immediately induced adventitious root of Dendrodium milla nayla x Dendrobium striaenopsis planted on coco-hust and wood charcoal
Authors: Rahayu Tintrim , Jayanti Gatra Ervi , Agisimanto Dita
Published: June 2022

Orchids are one of the most favorite cut flowers, flowering potted plants, and have developed into a highly profitable industry. The development of acclimatization method is a necessity for the high survival rate of plantlets. The aim of this study was to investigate the effect of low indole-3-butyric acid (IBA) concentration on faster root formation of Dendrobium hybrid planted on coco- husk and charcoal in a short time. Plantlets derived from the seed culture of Dendrodium milla nayla x Dendrobium striaenopsis were harvested and pre-acclimated, planted on charcoal or coco-husk, and regularly sprayed with 0.25, 0.50, 0.75, and 1.0 mg/L IBA twice a week for one month. The results showed that IBA at 0.50 mg/L provided the most appropriate concentration for immediate root induction and growth of Dendrobium hybrid planted on coco-husk. Root number (1.75) and root length (0.28 cm) showed the highest and the most important indicator of adventitious root induction
Diseño de un instrumento para medir la capacidad de gestión para resultados en la Universidad Juárez del Estado de Durango
Authors: De la Parra Northon Adolfo Antonio , Figueroa González Ernesto Geovani
Published: June 2022

En el actual proceso de globalización económica, las administraciones públicas buscan mejorar su operatividad y potenciar sus capacidades de gobiernos con resultados efectivos con el fin de crear prosperidad y desarrollo. Un enfoque utilizado con estos fines es el modelo de gestión para resultados, que basa sus resultados en políticas, programas y proyectos que ejecutan las administraciones públicas. El presente trabajo mide la capacidad de gestión para resultados (CGR) en la Universidad Juárez del Estado de Durango (UJED) por medio de un instrumento que aborda las tres dimensiones que conforman dicha capacidad. Se trata de un referente para evaluar la CGR en todas las instituciones con presupuesto gubernamental, un medio para arrojar luz a todas las organizaciones que pretendan mejorar sus prácticas con base en el modelo de gestión para resultados.
doutrina antidogmática do direito contratual
Authors: Amato Lucas Fucci
Published: June 2022

Tradicionalmente atribui-se à doutrina ou dogmática jurídica a tarefa de sistematizar e conferir coerência e unidade de sentido a determinado ramo do direito, tomando as normas postas vigentes como pressuposto incontornável de uma teorização voltada a informar a interpretação e aplicação do direito. Em contraste, este artigo procura descrever e analisar a proposta de uma doutrina jurídica estendida ou desviacionista, avançada no texto considerado como manifesto do movimento americano de estudos críticos do direito, de autoria de Roberto Mangabeira Unger. Ao lado da caracterização desse estilo de análise jurídica, que funciona como uma espécie de doutrina antidogmática, o texto discute o exemplo abordado por Unger: as construções dissonantes que se pode fazer do ramo do direito dos contratos, partindo do conflito entre princípios e contraprincípios constitutivos dessa seara. Finalmente, o texto aborda a crítica dirigida a tal teorização pelo pensador jusnaturalista contemporâneo John Finnis. Tal crítica revela a distância entre as posições morais e ideológicas avançadas, de um lado, pelos modernistas críticos, e, de outro, pelo direito natural de inspiração tomista. A conclusão é de que a exploração criativa das contradições existentes no interior da própria doutrina contratual pode ser mobilizada sobretudo no desenho de novos arranjos transacionais, especialmente daqueles voltados a contratos relacionais.
Devido processo legal constitucional e convencional:
Authors: Botana Menezes Aldo , Morgado Guarnieri Luciano
Published: June 2022

A efetividade de um processo devido perante as ações restritivas dos Estados, é um dos grandes temas em discussão na contemporaneidade. Entretanto, na américa latina e, principalmente no Brasil existe uma resistência para a devida efetividade dessas garantias. As democracias mais débeis, possuem uma tradição autoritária conservadora que insiste em sonegar garantias constitucionais e reconhecidas no cenário internacional. O devido processo legal convencional em auxílio ao constitucional é uma alternativa necessária para a mudança de paradigma no Brasil e na américa latina como um todo. Por meio do método analítico indutivo, buscou-se por meio desse ferramental, observar e analisar sua aplicação no contexto sócio-histórico-cultural do mundo ocidental, principalmente, objetivando como paradigma a observação constitucional de direitos fundamentais e de direitos humanos no Brasil.