bluuebunny/crossref_metadata_2025 huggingface dataset:
Análise do novo modelo de gestão do Parque Ibirapuera após licitação de 2019
Authors: Quinello Robson , Praim Camila Oliveira
Published: September 2024

Este estudo apresenta o processo de transição do modelo de gestão do Parque Ibirapuera, da cidade de São Paulo, antes pertencente à prefeitura e, após licitação de 2019, a uma concessão privada, apresentando as vantagens, as desvantagens, as oportunidades e os desafios sob a ótica do Facility Management (FM). Foi utilizada pesquisa-ação para descrever como está a gestão de um dos maiores parques da América do Sul e, por meio da ferramenta SWOT, demonstrar as dimensões dessa análise sob a perspectiva da gestão tripartite. Os resultados apontaram fatores positivos, como a profissionalização e a desburocratização da gestão, mas também desafios, como a busca por um olhar mais centrado no usuário e a construção de canais de comunicação com as entidades civis. Considerado um dos mais importantes parques urbanos da cidade de São Paulo, com uma complexa infraestrutura, ele foi gestado pela administração pública desde a sua fundação em 1954. A partir de 2019 o modelo muda para uma concessão privada com o objetivo de buscar eficiências operacionais. Poucos estudos falam sobre FM em parques, sobretudo aqueles sob concessão. O estudo joga luz na mudança radical de modelo de gestão, antes público e agora tripartite, buscando entender a dinâmica desse processo.
Review of Chinese species of genus Paramritodus Xue & Zhang (Hemiptera: Cicadellidae) with description of a new species
Authors: YU TINGTING , ZHU QIUYI , LI GUOQING , ZHANG BIN
Published: September 2024

The Chinese leafhopper species of the genus Paramritodus Xue & Zhang are reviewed. One new species, Paramritodus concavicaudus Zhang sp. nov., is described and illustrated from southwest China. Additionally, Paramritodus flavocapitatus (Cai & He, 2001) is proposed as a junior synonym of Paramritodus pistacious (Huang & Maldonado Capriles, 1992). A key to the species of the genus is also provided.
Fetal origin of bronchopulmonary dysplasia: contribution of intrauterine inflammation
Authors: Yu Haoting , Li Danni , Zhao Xinyi , Fu Jianhua
Published: September 2024

Bronchopulmonary dysplasia (BPD) is a common chronic lung disease in infants and the most frequent adverse outcome of premature birth, despite major efforts to minimize injury. It is thought to result from aberrant repair response triggered by either prenatal or recurrent postnatal injury to the lungs during development. Intrauterine inflammation is an important risk factor for prenatal lung injury, which is also increasingly linked to BPD. However, the specific mechanisms remain unclear. This review summarizes clinical and animal research linking intrauterine inflammation to BPD. We assess how intrauterine inflammation affects lung alveolarization and vascular development. In addition, we discuss prenatal therapeutic strategies targeting intrauterine inflammation to prevent or treat BPD.
Distal femoral fractures: periprosthetic fractures have four times more complications than non-periprosthetic fractures and cerclage should be avoided: retrospective analysis of 206 patients
Authors: Direder Martin , Naß Cornelia , Andresen Julian Ramin , Dannenmann Theresa , Bur Florian , Hajdu Stefan , Haider Thomas
Published: September 2024

Background

Distal femoral fractures account for less than 1% of all fractures. The therapy of choice is usually surgical stabilization. Despite advances in implant development over the past few years, complication rate remains comparatively high. The aim of this study is to analyze our results with plate fixation of distal femoral fractures with a focus on complication and fracture healing rates.

Methods

In this retrospective cohort study, patients (> 18 years) with distal femoral fractures treated at an urban level I trauma center between 2015 and 2022 were analyzed.

Results

In total, 206 patients (167 female, 39 male) with an average age of 75 (SD 16) years were diagnosed with a fracture of the distal femur. One hundred fourteen of these patients were treated surgically by means of plate osteosynthesis. In 13 cases (11.41%), a revision procedure had to be performed. The indication for surgical revision was mechanical failure in eight cases (7.02%) and septic complication in five cases (4.39%). Periprosthetic fractures were more likely to cause complications overall (19.6% versus 4.76%) and further included all documented septic complications. The analysis of modifiable surgical factors in the context of plate osteosynthesis showed higher complication rates for cerclage in the fracture area compared with plate-only stabilizations (44.44% versus 22.22%).

Conclusions

The data show an increased amount of revisions and a significantly higher number of septic complications in the treatment of periprosthetic fractures of the distal femur compared with non-periprosthetic fractures. The detected combination of plates together with cerclage was associated with higher complication rates.

Level of evidence Level III retrospective comparative study.
Emergency care via video consultation: interviews on patient experiences from rural community hospitals in northern Sweden
Authors: Ärlebrant Lina , Dubois Hanna , Creutzfeldt Johan , Edin-Liljegren Anette
Published: September 2024

Background

Delivering emergency care in rural areas can be challenging, but video consultation (VC) offers opportunities to make healthcare more accessible. The communication and relationship between professionals and patients have a significant impact on the patient’s experience of safety and inclusion. Understanding the patient perspective is crucial to developing good quality healthcare, but little is known about patient experiences of emergency care via VC in a rural context. The aim of this study was to explore patient experiences of emergency care via VC in northern rural Sweden.

Methods

Using a qualitative approach, semi- structured interviews (n = 12) were conducted with individuals aged 18—89 who had received emergency care with a registered nurse (RN) on site and VC with a general practitioner (GP). The interviews were conducted between October 2021 and March 2023 at community hospitals (n = 7) in Västerbotten County, Sweden. Interviews were analysed with content analysis.

Results

The analysis resulted in main categories (n = 2), categories (n = 5) and subcategories (n = 20). In the main category, “We were a team of three”, patients described a sense of inclusion and ability to contribute. The patients perceived the interaction between the GP and RN to function well despite being geographically dispersed. Patients highly valued the opportunity to speak directly to the GP. In the main category, “VC was a two-sided coin”, some experienced the emergency care through VC to be effective and smooth, while some felt that they received a lower quality of care and preferred face-to-face consultation with the GP. The quality of the VC was highly dependent on the RN’s ability to function as the hub in the emergency room.

Conclusion

Patients in rural areas perceived being included in 'the team' during VC, however they experienced disadvantages with the system on individual basis. The nursing profession plays an important role, and a proper educational background is crucial to support RNs in their role as the hub of the visit. The GP’s presence via VC was seen as important, but to fully enable them to fulfil their commitments as medical professionals, VC needs to be further improved with education and support from technical devices.
Population structure and breed identification of Chinese indigenous sheep breeds using whole genome SNPs and InDels
Authors: Zhao Chang-heng , Wang Dan , Yang Cheng , Chen Yan , Teng Jun , Zhang Xin-yi , Cao Zhi , Wei Xian-ming , Ning Chao , Yang Qi-en , Lv Wen-fa , Zhang Qin
Published: September 2024

Background

Accurate breed identification is essential for the conservation and sustainable use of indigenous farm animal genetic resources. In this study, we evaluated the phylogenetic relationships and genomic breed compositions of 13 sheep breeds using SNP and InDel data from whole genome sequencing. The breeds included 11 Chinese indigenous and 2 foreign commercial breeds. We compared different strategies for breed identification with respect to different marker types, i.e. SNPs, InDels, and a combination of SNPs and InDels (named SIs), different breed-informative marker detection methods, and different machine learning classification methods.

Results

Using WGS-based SNPs and InDels, we revealed the phylogenetic relationships between 11 Chinese indigenous and two foreign sheep breeds and quantified their purities through estimated genomic breed compositions. We found that the optimal strategy for identifying these breeds was the combination of DFI_union for breed-informative marker detection, which integrated the methods of Delta, Pairwise Wright's FST, and Informativeness for Assignment (namely DFI) by merging the breed-informative markers derived from the three methods, and KSR for breed assignment, which integrated the methods of K-Nearest Neighbor, Support Vector Machine, and Random Forest (namely KSR) by intersecting their results. Using SI markers improved the identification accuracy compared to using SNPs or InDels alone. We achieved accuracies over 97.5% when using at least the 1000 most breed-informative (MBI) SI markers and even 100% when using 5000 SI markers.

Conclusions

Our results provide not only an important foundation for conservation of these Chinese local sheep breeds, but also general approaches for breed identification of indigenous farm animal breeds.
Signals of positive selection in genomes of palearctic Myotis-bats coexisting with a fungal pathogen
Authors: Twort V. G. , Laine V. N. , Field K. A. , Whiting-Fawcett F. , Ito F. , Reiman M. , Bartonicka T. , Fritze M. , Ilyukha V. A. , Belkin V. V. , Khizhkin E. A. , Reeder D. M. , Fukui D. , Jiang T. L. , Lilley T. M.
Published: September 2024

Disease can act as a driving force in shaping genetic makeup across populations, even species, if the impacts influence a particularly sensitive part of their life cycles. White-nose disease is caused by a fungal pathogen infecting bats during hibernation. The mycosis has caused massive population declines of susceptible species in North America, particularly in the genus Myotis. However, Myotis bats appear to tolerate infection in Eurasia, where the fungal pathogen has co-evolved with its bat hosts for an extended period of time. Therefore, with susceptible and tolerant populations, the fungal disease provides a unique opportunity to tease apart factors contributing to tolerance at a genomic level to and gain an understanding of the evolution of non-harmful in host-parasite interactions. To investigate if the fungal disease has caused adaptation on a genomic level in Eurasian bat species, we adopted both whole-genome sequencing approaches and a literature search to compile a set of 300 genes from which to investigate signals of positive selection in genomes of 11 Eurasian bats at the codon-level. Our results indicate significant positive selection in 38 genes, many of which have a marked role in responses to infection. Our findings suggest that white-nose syndrome may have applied a significant selective pressure on Eurasian Myotis-bats in the past, which can contribute their survival in co-existence with the pathogen. Our findings provide an insight on the selective pressure pathogens afflict on their hosts using methodology that can be adapted to other host-pathogen study systems.
Gender-related stigma toward individuals with a history of sexual or physical violence in childhood
Authors: Rechenberg Theresia , Fleischer Toni , Sander Christian , Schomerus Georg
Published: September 2024

Background

Stigma is a key barrier to disclosing traumatic experiences of violence in childhood with adverse consequences for help-seeking behaviour. Disclosing behavior differs by gender and the form of violence experienced. However, there is a lack of comprehensive studies that address societal perceptions of males and females with a history of sexual or physical violence in childhood. Therefore, our aim is to focus on the impact of gender on the perception of individuals who experienced sexual or physical violence in childhood.

Methods

We conducted a study on a representative sample of the German general population in terms of age and gender. Participants were randomly assigned to brief case vignettes addressing sexual or physical violence in childhood. Analyses base on a sample of n = 659 individuals (50.1% female). Stigma was assessed through examining respondents’ readiness to address specific traumas in conversation and respondents’ attitudes toward the individuals in the vignettes. Mann–Whitney U tests were applied to check for differences between female and male victims and survivors as well as female and male respondents.

Results

Our results reveal that male victims and survivors face higher negative stereotypes (harm, unpredictability) and evoke communication barriers more often when compared to female victims and survivors, especially in male respondents. Sexual violence is associated with more distinct gender differences than physical violence.

Conclusions

Findings reflect greater stigma toward male victims and survivors of sexual violence than female ones. Men had a greater tendency to stigmatize – especially toward their same-gender peers. Socially ingrained gender roles may act as a basis for different communication cultures and the notion of victim-perpetrator constellations in which males are not envisaged as victims.
Study on the association between malnutrition, early childhood caries and caries activity among children aged 3–5 years
Authors: Wang Duorui , Wang Xinfeng , Zhao Caiyun , Ma Siting , Zhang Yanning , Shi Hong
Published: September 2024

Background

This study aims to investigate the association between malnutrition and early childhood caries (ECC) and caries activity among children aged 3–5 years, in order to provide a theoretical basis for preventing and blocking ECC and improving malnutrition.

Methods

Children aged 3–5 years from six kindergartens in Zhao Xian, China were enrolled in this study. The decayed, missing, filled teeth (dmft) of all children were examined and recorded. The Cariostat method was used to detect dental caries activity, collect anthropometric data and measure haemoglobin concentration. Parents were asked to complete a questionnaire on the general characteristics and oral health behaviour of the participants. The “Growth Standards for Chinese Children Under 7 Years Old” was used to assess the nutritional status of all participating children. Wilcoxon rank sum test and multivariate logistic regression analysis were used to analyse and evaluate the relationship between ECC, caries activity and malnutrition.

Results

A total of 635 children who met the criteria were included in this study. After adjusting for confounding factors, logistic regression showed that the risk of ECC was significantly increased in underweight children compared with normal children (OR = 5.43, P < 0. 05); compared with normal children, the risk of ECC decreased in overweight and obese children (OR = 0.31, P < 0.001); underweight children had higher caries severity than normal weight children, and the difference was statistically significant (OR = 2.69, P < 0. 05); stunted children had higher caries severity than normal weight children and the difference was statistically significant (OR = 2.28, P < 0.05); underweight was positively associated with caries activity and the association was statistically significant (OR = 2.33, P < 0. 05); stunting was positively associated with caries activity and the association was statistically significant (OR = 2.1, P < 0.05); overweight and obesity were negatively associated with caries activity and the association was statistically significant (OR = 0.61, P < 0.05).

Conclusions

The risk of ECC among children aged 3–5 years was positively associated with undernutrition and negatively associated with overnutrition. The severity of ECC among children aged 3–5 years was positively associated with undernutrition. The caries activity among children aged 3–5 years was positively associated with undernutrition and negatively associated with overnutrition.
Exploring the mortality and cardiovascular outcomes with SGLT-2 inhibitors in patients with T2DM at dialysis commencement: a health global federated network analysis
Authors: Wang Chung-An , Lin Li-Chun , Chen Jui-Yi , Wang Wei-Jie , Wu Vin-Cent
Published: September 2024

Background

Sodium-glucose cotransporter 2 inhibitors (SGLT-2is) have demonstrated associations with lowering cardiovascular outcomes in patients with type 2 diabetes mellitus (T2DM). However, the impact of SGLT-2is on individuals at dialysis commencement remains unclear. The aim of this real-world study is to study the association between SGLT-2is and outcomes in patients with T2DM at dialysis commencement.

Methods

This is a retrospective cohort study of electronic health records (EHRs) of patients with T2DM from TriNetX Research Network database between January 1, 2012, and January 1, 2024. New-users using intention to treatment design was employed and propensity score matching was utilized to select the cohort. Clinical outcomes included major adverse cardiac events (MACE) and all-cause mortality. Safety outcomes using ICD-10 codes, ketoacidosis, urinary tract infection (UTI) or genital infection, dehydration, bone fracture, below-knee amputation, hypoglycemia, and achieving dialysis-free status at 90 days and 90-day readmission.

Results

Of 49,762 patients with T2DM who initiated dialysis for evaluation, a mere 1.57% of patients utilized SGLT-2is within 3 months after dialysis. 771 SGLT-2i users (age 63.3 ± 12.3 years, male 65.1%) were matched with 771 non-users (age 63.1 ± 12.9 years, male 65.8%). After a median follow-up of 2.0 (IQR 0.3–3.9) years, SGLT-2i users were associated with a lower risk of MACE (adjusted Hazard Ratio [aHR] = 0.52, p value < 0.001), all-cause mortality (aHR = 0.49, p < 0.001). SGLT-2i users were more likely to become dialysis-free 90 days after the index date (aHR = 0.49, p < 0.001). No significant differences were observed in the incidence of ketoacidosis, UTI or genital infection, hypoglycemia, dehydration, bone fractures, below-knee amputations, or 90-day readmissions.

Conclusions

Our findings indicated a lower incidence of all-cause mortality and MACE after long-term follow-up, along with a higher likelihood of achieving dialysis-free status at 90 days in SGLT-2i users. Importantly, they underscored the potential cardiovascular protection and safety of SGLT-2is use in T2DM patients at the onset of dialysis.
Sonic Hedgehog reduces inflammatory response, decreases blood-spinal cord barrier permeability, and improves locomotor function recovery in an acute spinal cord injury rat model
Authors: Tail Mohamed , Zhang Hao , Zheng Guoli , Harms Anna-Kathrin , Hatami Maryam , Skutella Thomas , Kiening Karl , Unterberg Andreas , Zweckberger Klaus , Younsi Alexander
Published: September 2024

Background

Sonic Hedgehog (Shh), extensively researched for its role in early neurogenesis and brain development, has recently been recognized for its neuroprotective potential following neuronal injuries. This study examines the immediate impact of early administered Shh on the local inflammatory response post-acute spinal cord injury in rats.

Methods

Thirty-four female Wistar rats underwent either sham surgery (laminectomy; n = 10) or clip compression/contusion spinal cord injury (SCI) at the T9 level. This was followed by implantation of an osmotic pump and a subdural catheter for continuous intrathecal delivery of Shh (n = 12) or placebo (NaCl; n = 12). Locomotor function was assessed at 3- and 7-days post-injury (dpi) using the Basso, Beattie, and Bresnahan (BBB) score and the Gridwalk test. Animals were euthanized after 3 or 7 days for immunohistochemical analysis of the local inflammatory reaction and immune cell migration.

Results

Shh-treated rats demonstrated significant hindlimb movement and coordination improvements at 7 days post-injury, compared to controls. This enhancement was accompanied by a significant reduction in both immune cell presence and blood plasma products within spinal cord lesions, suggesting Shh’s dual role in modulating immune cell migration and maintaining the integrity of the blood-spinal cord barrier. Separately, these Shh-treated rats also showed an increase in M(IL-4) polarization of macrophages, further underlining the potential therapeutic impact of Shh in post-injury recovery. Notably, these effects were not evident at three days post-injury.

Conclusion

Shh application at 7 days post-injury showed immunomodulatory effects, possibly via enhanced blood-spinal cord barrier integrity, reduced immune cell migration, and increased anti-inflammatory immune cell differentiation. These mechanisms collectively contribute to enhanced locomotor recovery.
Reflective functioning and emotion regulation in adolescents with a history of sexual offending: a comparative study with a non-offending control group
Authors: Pazhooyan Mahdieh , Fathali Lavasani Fahimeh , Edalati Shateri Zohreh , Zahedi Tajrishi Komeil
Published: September 2024

Background

Sexual offenses encompass a diverse array of behaviors across various contexts, affecting numerous individuals. Despite the prevalence of sexual offending among adolescents, there is still a limited understanding of this population. To contribute further to the literature in this field, the present study was conducted to compare a group of male adolescents convicted of sexual offenses with a control group in terms of reflective functioning (RF), emotion regulation (ER) strategies, and emotion dysregulation (ED).

Methods

60 male adolescents aged 12 to 18 years (M = 16.90;SD = 0.97) who had been convicted of at least one serious sexual offense were recruited from male adolescents referred by juvenile courts to the Legal Medicine Organization in Mashhad, Iran, and compared with a control group of non-offending adolescents consisting of 60 male adolescents aged 12 to 18 years (M = 16.97;SD = 0.82) who were attending school. The groups were matched on age and education level.

Results

A comparison between these two groups revealed that adolescents with a history of sexual offending exhibited poorer RF capacity, greater use of suppression as an ER strategy, and higher scores in all ED domains (p’s < 0.001) except non-acceptance of emotional responses compared with the control group.

Conclusions

Results suggest that RF, ER strategies, and ED need to be considered as important psychological factors in understanding and treating adolescents with a history of sexual offending.
RNAseqCovarImpute: a multiple imputation procedure that outperforms complete case and single imputation differential expression analysis
Authors: Baker Brennan H. , Sathyanarayana Sheela , Szpiro Adam A. , MacDonald James W. , Paquette Alison G.
Published: September 2024

Missing covariate data is a common problem that has not been addressed in observational studies of gene expression. Here, we present a multiple imputation method that accommodates high dimensional gene expression data by incorporating principal component analysis of the transcriptome into the multiple imputation prediction models to avoid bias. Simulation studies using three datasets show that this method outperforms complete case and single imputation analyses at uncovering true positive differentially expressed genes, limiting false discovery rates, and minimizing bias. This method is easily implemented via an R Bioconductor package, RNAseqCovarImpute that integrates with the limma-voom pipeline for differential expression analysis.
Daily Bi-directional effects of women’s social media-based appearance comparisons, body satisfaction, and disordered eating urges
Authors: Portingale Jade , Girardin Simone , Liu Shanshan , Fuller-Tyszkiewicz Matthew , Krug Isabel
Published: September 2024

We assessed the bi-directional relationships between upward appearance comparisons on social media with body dissatisfaction (BD) and disordered eating (DE) in women’s daily lives and the potential moderating effect of trait self-objectification on these relationships. Women (N = 315) completed a baseline measure of trait self-objectification, then reported momentary experiences of social media-based appearance comparisons (upward, lateral, downward), body satisfaction, and DE urges (restrict food intake, exercise, overeat) for seven days. We hypothesized that upward (relative to no) comparisons would predict lower body satisfaction and higher DE urges, while lateral and downward (relative to no) comparisons would predict higher body satisfaction and lower DE urges. We expected these relationships to be bi-directional and moderated by trait self-objectification. Multilevel modelling results revealed complex bi-directional relationships. Upward comparisons predicted lower body satisfaction and increased urges to restrict food intake, which in turn predicted increased upward comparisons. Unexpectedly, urges to restrict food intake predicted all comparison types. We observed somewhat unanticipated bi-directional relationships between lateral comparisons and exercise urges, and between downward comparisons and body satisfaction. Uni-directional relationships emerged between upward comparisons and the urge to overeat. Trait self-objectification moderated very few of these relationships. These findings support the non-uniform impact of appearance comparisons on body image and eating concerns and highlight the complexity of daily social media-body image dynamics. Future research using refined measures over extended periods is needed to elucidate these relationships further and inform targeted interventions.
Concurrent ependymal and ganglionic differentiation in a subset of supratentorial neuroepithelial tumors with EWSR1-PLAGL1 rearrangement
Authors: Lee Julieann C. , Koo Selene C. , Furtado Larissa V. , Breuer Alex , Eldomery Mohammad K. , Bag Asim K. , Stow Pat , Rose Gary , Larkin Trisha , Sances Rick , Kleinschmidt-DeMasters Bette K. , Bodmer Jenna L. , Willard Nicholas , Gokden Murat , Dahiya Sonika , Roberts Kaleigh , Bertrand Kelsey C. , Moreira Daniel C. , Robinson Giles W. , Mo Jun Qin , Ellison David W. , Orr Brent A.
Published: September 2024

Neuroepithelial tumors with fusion of PLAGL1 or amplification of PLAGL1/PLAGL2 have recently been described often with ependymoma-like or embryonal histology respectively. To further evaluate emerging entities with PLAG-family genetic alterations, the histologic, molecular, clinical, and imaging features are described for 8 clinical cases encountered at St. Jude (EWSR1-PLAGL1 fusion n = 6; PLAGL1 amplification n = 1; PLAGL2 amplification n = 1). A histologic feature observed on initial resection in a subset (4/6) of supratentorial neuroepithelial tumors with EWSR1-PLAGL1 rearrangement was the presence of concurrent ependymal and ganglionic differentiation. This ranged from prominent clusters of ganglion cells within ependymoma/subependymoma-like areas, to interspersed ganglion cells of low to moderate frequency among otherwise ependymal-like histology, or focal areas with a ganglion cell component. When present, the combination of ependymal-like and ganglionic features within a supratentorial neuroepithelial tumor may raise consideration for an EWSR1-PLAGL1 fusion, and prompt initiation of appropriate molecular testing such as RNA sequencing and methylation profiling. One of the EWSR1-PLAGL1 fusion cases showed subclonal INI1 loss in a region containing small clusters of rhabdoid/embryonal cells, and developed a prominent ganglion cell component on recurrence. As such, EWSR1-PLAGL1 neuroepithelial tumors are a tumor type in which acquired inactivation of SMARCB1 and development of AT/RT features may occur and lead to clinical progression. In contrast, the PLAGL2 and PLAGL1 amplified cases showed either embryonal histology or contained an embryonal component with a significant degree of desmin staining, which could also serve to raise consideration for a PLAG entity when present. Continued compilation of associated clinical data and histopathologic findings will be critical for understanding emerging entities with PLAG-family genetic alterations.
President's Page: Participation and “duty of care”
Authors: Eastwood John
Published: September 2024

This is my last President's Page as active SEG president. I would like to take this opportunity to reflect on the past year as SEG president and share
Earth Science Week offers activities for all
Authors: Mossa Lindsay C. , Brase Lauren , McGee Sequoyah , Robeck Edward C.
Published: September 2024

Earth science plays a crucial role in all aspects of the environment, society, and economy. Earth Science Week (ESW) is an annual celebration that highlights the importance of studying the earth with the aim of drawing more people into the geosciences.
Reviews
Authors: Aitken Julie
Published: September 2024

Active Seismic Tomography: Theory and Applications, by Kalachand Sain and Damodara Nara, 2023 Distributed Acoustic Sensing for Seismic Measurements — What Geophysicists and Engineers Need to Know, by Mark E. Willis, 2022
Repatriation via Saigon
Authors: Ryan Thomas M.
Published: September 2024

The South Korean Vietnam War deployment (1965–73), typically understood as a mercenary expedition, was also an exercise in the management of refugees and other displaced populations. While the South Korean Army managed its own refugee villages in South Vietnam, the overseas dispatch of military labor also promised to ameliorate the problem of mass displacement at home, an ongoing legacy of the Korean War (1950–53). The northern exile writer Sŏnu Hwi (1922–86) was a notable proponent of this vision of the war as a frontier, framing Vietnam as a surrogate for an inaccessible North Korea and an outlet for the social contradictions of Cold War developmentalism in South Korea. Focusing on the embedded novel Wave to the Mekong River (1966–67), this article argues that Sŏnu's expansionist fantasy deviated from official justifications of Vietnam as a war for development. At the same time, it suggests, Sŏnu's ideological equalization of exile and displacement also informed an emergent antiwar literature showing that the deployment aggravated, rather than resolved, the marginalization of mobilized youth.
The separation of investment banking activities from the universal banking model as a (precautionary) supervisory and regulatory measure for preventing financial instability events
Authors: Μπομπότης Νικήτας
Published: September 2024

Η παρούσα διδακτορική διατριβή εξετάζει και αναλύει το ζήτημα του επιβαλλόμενου διαχωρισμού, μεταξύ των υπηρεσιών επενδυτικής και λιανικής τραπεζικής, όπου αυτός επιβάλλεται για σκοπούς διασφάλισης της χρηματοπιστωτικής σταθερότητας και αποφυγής χρηματοπιστωτικών κρίσεων. Στην εν λόγω διατριβή, εξετάζεται και αναλύεται συγκριτικά, το καθεστώς διαχωρισμού που έχει επιβληθεί σε δείγμα 5 διαφορετικών κρατών, μεταξύ των οποίων και η ΕΕ, παρουσιάζονται τα υπέρ και τα κατά της κάθε ειδικότερης προσέγγισης, αναλύονται στη βάση της ιστορικής τους προέλευσης και στο τέλος επιχειρείται μία συγκριτική προσέγγιση των λύσεων που παρέχονται από το κάθε καθεστώς, απαντώντας στο ερώτημα εάν ο διαχωρισμός των υπηρεσιών επιβάλλεται δικαιολογημένα ή όχι και αν πετυχαίνει το στόχο που είχε τεθεί με τη θέσπισή του. Στο πλαίσιο της παρούσας διατριβής μελετάται και αναλύεται επίσης η σχέση που αναπτύσσεται μεταξύ των καθεστώτων διαχωρισμού και συγκεκριμένων θεματικών που σχετίζονται με την προσπάθεια για τη διασφάλισης της σταθερότητας του χρηματοπιστωτικού συστήματος.
HYBRID WORKING MODEL: PRO ET CONTRA
Authors: Konovalova Valeriya
Published: September 2024

The article is devoted to the study of the prospects and problems of developing a hybrid work model, which has already become an inevitable solution for many organizations. The main options for implementing the hybrid model are presented, as well as other advantages compared to traditional office work and completely remote work. Typical problems arising in a hybrid environment and their manifestations in such areas as communications and cooperation, professional development, corporate culture, staff well-being, productivity and motivation, technological safety are highlighted). It is shown that the features of hybrid work often conflict with established management practices. Based on a generalization of experience in implementing a hybrid work model, national and global studies, recommendations are substantiated to overcome difficulties and find the optimal balance between the advantages and disadvantages of working in a hybrid environment.
Optimization of Volumetric Ratio of Soy Milk and Concentration of Porang Gel on the Properties of Soy Milk Fortified with Ginger Extract
Authors: Mubarok Ahmad Zaki , Samesta Ocha Salma
Published: September 2024

Soy milk is a typical soy protein product and a good source of essential nutrients, however “beany” off-flavor makes soy milk unpleasant or unacceptable to many consumers. The addition of ginger extract in this research is intended to mask the “beany” off-flavor in soy milk. Soy milk is a beverage with an emulsion system that exhibits unstable characteristics during storage. Creaming and sedimentation in protein-rich beverages can be addressed by enhancing system stability using polysaccharides such as glucomannan from the porang plant. Glucomannan has the ability to bind water effectively, restricting molecular movement and thereby improving the stability of soy milk. The objective of this research is to determine the optimal values for volumetric ration of soy milk and concentration of porang gel that yield the desired responses in terms of physical stability, viscosity, and antioxidant activity of soy milk using response surface methodology. The models predicted that the optimal formula was soy milk volumetric ratio of 69.3 (v/v) and porang gel concentration of 1.3%. The verification experiments were conducted in three replications. The results showed that physical stability, viscosity and IC50 value of soy milk were 0.90±0.05, 132.0±5.5 cP and 187.5±35.2 ppm under optimal formulation. The optimization results were validated and found no statistically significant differences at a 5% significance level. Soy milk with good physical stability, viscosity, and antioxidant activity can be prepared with this formulation.
childism and minority cultures in school
Authors: Snir Itay
Published: September 2024

While inequality between children and adults characterizes practically every aspect of contemporary society, school is considered a paradigmatic site of adult domination. Childist critiques tend to point to school as a place where adultism is not only conspicuous but also (re)produced. In this article, however, it is argued that the public school, obviously founded by adults for adult purposes, has an important childist dimension. Although it is based on a clear distinction between adult teachers and child students, school can problematize key adultist norms and promote a more age-equal society. This does not imply that exiting schools are necessarily childist, but rather that a certain understanding of the school, which emphasizes its social-democratic significance, can uncover its childist aspects and build on them when reimagining public education. The conception of the school in which the article focuses is presented in Jan Masschelein and Maarten Simons’ 2013 book In Defence of the School: A Public Issue. Although the authors do not refer directly to childism (or child equality), and are clearly writing from an adultist perspective, I argue that the public school they describe does have a childist dimension: it challenges one of the root causes of adultism: considering children the property of their parents. Nevertheless, Masschelein and Simons’ conception of the school raises a problem of its own, which also has a childist aspect: the concern that uniform schooling supervised by the state will be detrimental to minority and indigenous groups, imposing a culture and identity determined by adults. The second part of this article addresses this concern, arguing that genuine school education can be key not only to preserving but also to revitalizing minority cultures and identities by allowing the students to bring their “newness” into the encounter with the cultures and identities of their families.
PRODUÇÃO DE CONHECIMENTO SOBRE PRÁTICAS CORPORAIS NA EDUCAÇÃO FÍSICA BRASILEIRA ENTRE 2012 E 2022.
Authors: do Vale Lennon Oliveira Pereira , Furtado Renan Santos , Correia Mesaque Silva
Published: September 2024

O presente estudo aborda o lugar da categoria práticas corporais na recente produção de conhecimento em Educação Física, com foco em três periódicos da área vinculados ao campo das ciências humanas e sociais. Desse modo, o objetivo geral consiste em compreender o lugar da categoria práticas corporais em artigos que versam sobre Educação Física escolar, publicados entre 2012 e 2022 em periódicos científicos da área. Metodologicamente, por via da técnica da análise de conteúdo e a partir do termo-chave de busca do material denominado “Práticas corporais e Educação Física escolar”, estudamos quatorze trabalhos publicados nas Revistas: Movimento, Conexões e Corpoconsciência. Assim, como síntese explicativa deste movimento de pesquisa, destacam-se as seguintes categorias explicativas: 1) Práticas Corporais e questões de Diversidade, Sexualidade e Religiosidade; 2) Práticas corporais outras e transversalidades; 3) Práticas corporais e Educação Física Escolar. O estudo aponta a diversificação dos debates em torno da noção de práticas corporais quando conectada com a Educação Física escolar na contemporaneidade. Sendo assim, a discussão evidencia certo acúmulo da área da Educação Física em conceber as práticas corporais como objeto de conhecimento da disciplina na escola, bem como a emergência de questões de diversidade e a demanda pela diversificação das experiências corporais proporcionadas pelo currículo escolar.
#SOUPRINCESASOUREAL:
Authors: Lina Martina Torres das Neves Formentin  Possui Bárbara , Corpes Magalhães Joanalira , Costa Ribeiro Paula Regina
Published: September 2024

Este texto tem, como proposta, analisar três vídeos que compõem a Campanha #SouPrincesaSouReal da Disney, no Brasil, a fim de discutir como as produções midiáticas dessa campanha ensinam e (re)produzem determinadas formas de ser menina/ser mulher. Fundamentamos as discussões a partir dos Estudos Culturais e Estudos de Gênero, nas vertentes pós-estruturalistas. A partir de algumas ferramentas da análise cultural, selecionamos e analisamos três vídeos promocionais da referida campanha, com o intuito de discutirmos a representação das meninas e princesas, além dos endereçamentos presentes nesses artefatos culturais, por meio das imagens e das trilhas sonoras. Para tanto, organizamos dois eixos de análise: no primeiro eixo, denominado “‘Determinada e sonhadora’ – Entre meninas e princesas: discutindo os endereçamentos presentes nos vídeos promocionais”, buscamos discutir que relação existe entre as narrativas apresentadas nos vídeos com meninas, com os elementos empregados para endereçar esses artefatos culturais para o público infantojuvenil feminino. Já no segundo eixo, “‘Sonhe alto, sempre tem uma princesa que mostra que é possível’: discutindo o entrelaçamento entre ideia de empoderamento feminino da campanha com a filosofia dos sonhos”, analisamos o uso da filosofia de que sonhar é desejar, e os sonhos se realizam. Tal filosofia foi cunhada pela Walt Disney Company e foi entrelaçada à ideia de empoderamento feminino, presente na campanha #SouPrincesaSouReal da Disney. A realização do presente estudo nos possibilitou compreender a potência que um artefato midiático cultural desenvolvido por uma grande corporação midiática, a Disney, e por um movimento social relacionado à Organização das Nações Unidas, Girl Up, o qual tem a proposta de produzir e de ensinar, de forma pedagógica, modos variados de ser menina e mulher no mundo.
FILMES DE ANIMAÇÃO PRODUZIDOS COM CRIANÇAS:
Authors: Xavier Filha Constantina
Published: September 2024

O cinema é um dispositivo poderoso e capaz de possibilitar a descoberta e o conhecimento de si, das outras pessoas e de inventar outros mundos, de nos ver de diferentes pontos de vistas e, sobretudo, de nos fazer pensar o que somos, o que fizeram de nós e o que queremos/podemos ser.  O presente texto tem por objetivo pensar sobre a potencialidade do cinema a partir de produções coletivas realizadas com crianças em projetos realizados no Brasil e em Portugal. Trata-se de pesquisa em andamento, para a qual se entrevistaram professoras/es-cineastas dos dois países, buscando coletar, discutir e problematizar suas narrativas sobre encontros com o cinema na produção de filmes de animação com crianças. Neste texto, tem-se buscado, mais especificamente, selecionar e analisar dois filmes de animação produzidos com as crianças nas experiências de projetos, um deles realizado por um cineasta-professor português, e outro, de minha experiência de produção com as crianças. O artigo se propõe algumas problematizações em torno das semelhanças e diferenças que se podem observar nas produções de um e outro país. Na análise dos filmes, atentou-se para a riqueza de argumentos das crianças, para a eficiência do pensamento gerado nas produções audiovisuais e para a repercussão do tema seja junto ao grupo, como coletividade, seja sobre cada um, como individualidade.
PRODUÇÃO CURRICULAR COM AS CRIANÇAS - BILHETES, “WHATSAPP DE PAPEL” E AS VIVÊNCIAS COM A ESCRITA
Authors: Axer Bonnie
Published: September 2024

Uma criança perguntou à professora o que seria um bilhete e teve a sua pergunta respondida por outra criança: “bilhete é como se fosse um whatsapp de papel”. Assim aconteceu na turma 21 o “WhatsApp de papel”, uma forma particular de interação e prática de escrita diária que os acompanhou em sala de aula. Para pensar os processos educativos e curriculares das infâncias e seus atravessamentos culturais, parto dessa experiência curricular – a troca de bilhetes (entre crianças e destas com as professoras), entendendo tal movimento como estratégia das próprias crianças de manutenção no presencial do uso que faziam dos chats nas aulas online. Para dialogar e desdobrar esta vivência, me apoio na perspectiva discursiva da alfabetização (GOULART; SANTOS, 2017; GOULART,2019; SMOLKA,2012) e da produção curricular (LOPES; MACEDO, 2011), assumindo ambos os processos como textos em movimento, inacabados, numa relação em abertura (DERRIDA, 1971) com a significação. Sendo assim, atravessada e mobilizada por sentidos inesperados e inventivos, este artigo é fruto de reflexões, experiências e investimentos teórico-metodológicos feitos em diálogo com os campos do currículo e alfabetização com a premissa que somos todos sujeitos da linguagem (crianças e professoras). Reflexões estas que têm me levado à aposta que a maneira como se lida com o currículo em sala precisa levar em consideração o entendimento acerca da aprendizagem da leitura e da escrita por parte da criança e da sua relação com os adultos, com seus pares e com o mundo à sua volta.
Rethinking Kawasaki disease diagnosis: Continuing the search for new biomarkers
Authors: Pan Yan , Jiao Fu-Yong
Published: September 2024

Recent findings by Yamashita et al report a Kawasaki disease (KD) case with normal biomarker levels, challenging traditional diagnostic paradigms. This editorial explores the implications of such atypical KD presentations, emphasizing the need for novel biomarkers and revised diagnostic guidelines. The case underscores the limitations of current biomarkers, the importance of clinical judgment, and the necessity for comprehensive research to identify new diagnostic tools. Emerging technologies in proteomics and genomics offer potential avenues for discovering reliable biomarkers. Revisiting clinical guidelines to incorporate flexibility for atypical presentations is crucial. Ensuring timely and accurate KD diagnosis, even without elevated traditional biomarkers, prevents severe complications. Future advancements should focus on novel biomarkers to improve patient outcomes.
Global strategy for prevention of gastric cancer
Authors: Kotelevets Sergey M
Published: September 2024

Global prevention of gastric cancer needs to increase its level of effectiveness. The prevention strategy should include all stages of primary and secondary prevention. The necessary steps to prevent gastric cancer are the following: Maintaining a healthy lifestyle and diet, avoiding smoking and alcohol; serological screening of Helicobacter pylori infections and eradication; serological screening of atrophic gastritis in the population over 45 years of age and identification of severe atrophic gastritis with a high risk of developing gastric cancer; verification of atrophic gastritis and precancerous changes in the gastric mucosa using modern endoscopic (confocal laser endomicroscopy, narrow-spectrum imaging, and magnifying endoscopy) and morphological methods among patients with severe atrophic gastritis who were identified using serological screening; treatment of patients with atrophic gastritis during diagnosis verification; annual endoscopic and morphological monitoring of patients with atrophic gastritis during permanent treatment; annual serological monitoring of patients with atrophic gastritis who refused endoscopic and morphological monitoring; and radical treatment of patients with verified early gastric cancer. Ways to implement the algorithm for the global strategy for the prevention of gastric cancer (protocol of practical recommendations) are: State, government, and municipal programs; departmental programs of health departments; family doctors for patients who have a contract at the initiative of the doctor; family doctors for patients with a contract at the patient’s initiative; and within private healthcare system where both doctors and patients can initiate the implementation of algorithm.
Functional investigation and two-sample Mendelian randomization study of primary biliary cholangitis hub genes
Authors: Yang Yun-Chuan , Ma Xiang , Zhou Chi , Xu Nan , Ding Ding , Ma Zhong-Zheng , Zhou Lei , Cui Pei-Yuan
Published: September 2024

BACKGROUND

The identification of specific gene expression patterns is crucial for understanding the mechanisms underlying primary biliary cholangitis (PBC) and finding relevant biomarkers for diagnosis and therapeutic evaluation.

AIM

To determine PBC-associated hub genes and assess their clinical utility for disease prediction.

METHODS

PBC expression data were obtained from the Gene Expression Omnibus database. Overlapping genes from differential expression analysis and weighted gene co-expression network analysis (WGCNA) were identified as key genes for PBC. Kyoto Encyclopedia of Genes and Genomes and Gene Ontology analyses were performed to explore the potential roles of key genes. Hub genes were identified in protein-protein interaction (PPI) networks using the Degree algorithm in Cytoscape software. The relationship between hub genes and immune cells was investigated. Finally, a Mendelian randomization study was conducted to determine the causal effects of hub genes on PBC.

RESULTS

We identified 71 overlapping key genes using differential expression analysis and WGCNA. These genes were primarily enriched in pathways related to cytokine-cytokine receptor interaction, and Th1, Th2, and Th17 cell differentiation. We utilized Cytoscape software and identified five hub genes (CD247 , IL10 , CCL5 , CCL3 , and STAT3 ) in PPI networks. These hub genes showed a strong correlation with immune cell infiltration in PBC. However, inverse variance weighting analysis did not indicate the causal effects of hub genes on PBC risk.

CONCLUSION

Hub genes can potentially serve as valuable biomarkers for PBC prediction and treatment, thereby offering significant clinical utility.