bluuebunny/crossref_metadata_2025 huggingface dataset:
Edukasi Media Interaktif untuk Meningkatkan Pengetahuan Siswa Bijak Bermedia Sosial di Desa Bonde Utara Kecamatan Pamboang Kabupaten Majene
Authors: Pertiwi Nurlita , Mandra Moh. Ahsan S. , Arif Muhammad Ridwan
Published: March 2024

Mitra Program Kemitraan Masyarakat (PKM) ini adalah siswa SMP di Kabupaten Majene, Desa Bonde Utara. Metode yang digunakan pada pelatihan ini ada dua yakni kegiatan edukasi dengan metode ceramah tentang cara bijak bermedia sosial. Tahap kedua adalah pelatihan pembuatan video interaktif dan mensyaratkan siswa membuat satu video yang menggunakan foto dan video aktivitas pribadinya.Â  Fokus materi yang diberikan adalah pembuatan video edukasi dengan menggunakan aplikasi capcut. Sebanyak 25 siswa yang terlibat dalam kegiatan ini. Hasil yang dicapai adalah peningkatan pengetahuan dan keterampilan peserta dalam membuat video tentang potensi yang ada di sekitarnya.
Pelatihan Konsep Gamification Profiling Pada SMA Negeri 3 Semarang
Authors: Gamayanto Indra , Haryanto Hanny , Harisa Ardiawan Bagus , Setiawan Abas
Published: March 2024

Gamification merupakan fenomena luar biasa mengenai bagaimana kita dapat melibatkan pengguna untuk dapat memahami bisnis yang kita miliki. Para pengguna akan dapat memperoleh banyak hal yang menarik dari gamification yang ditawarkan oleh para pemilik bisnis, mulai dari game, bonus, discount, dan masih banyak hal lainnya yang dapat membuat pengguna atau konsumen menjadi lebih loyal dan memiliki hubungan yang erat dengan bisnis tersebut. Penelitian ini merupakan pengembangan konsep dari innovation profiling, dimana konsep ini menjelaskan mengenai tujuh tipe inovasi dan di sini gamification merupakan salah satu inovasi yang akan kami bahas. Pada penelitian ini, gamification dibagi menjadi tiga bagian penting, dimana hal ini merupakan kesatuan yang tidak boleh dipisahkan satu sama lain. Pada bagian pertama adalah tentang the big picture of gamification profiling dan formula GMF = P. B2. E2. I2. U2. Pada tahap kedua adalah empat tipe gamification- open gamification (OP), specific gamification (SG), innovative gamification (IG), undeveloped gamification (UG). Pada tahap ketiga, yang merupakan tahap akhir adalah Business gamification profiling (BG), Education gamification profiling (EG), Psikologi gamification profiling (PG), Future gamification profiling (FG). Hasil dari penelitian ini adalah framework gamification profiling dan penerapannya pada bidang education, sebagai studi kasus utama dalam menerapkan hal ini.
Sistem Informasi Pengarsipan Surat Gereja Masehi Injili di Timor (GMIT) Genesaret Danau Ina Berbasis Web
Authors: Amos Pah Clarissa Elfira , Tas’au Emilia , Seran Delsiana Osi , Ledoh Juan Rizky Mannuel
Published: March 2024

Era industri 4.0 memicu berbagai perusahaan untuk menggunakan teknologi informasi dalam mendukung proses bisnisnya, tidak terkecuali untuk perusahaan atau organisasi non-profit seperti Gereja Masehi Injili di Timor Genesaret Danau Ina (GMIT GDI). GMIT GDI melakukan pelayanan terhadap jemaatnya yang berlokasi di Lasiana, Kota Kupang, Nusa Tenggara Timur. Salah satu pelayanan yang dilakukan adalah pendataan dan pengarsipan surat masuk dan surat keluar. Masalah yang terjadi adalah pendataan surat-surat ini masih dilakukan pada buku agenda fisik yang rentan terhadap kerusakan dan kehilangan, sehingga untuk mengatasinya dibutuhkan sebuah sistem pendataan dan pengarsipan surat berbasis web. Kelebihan sistem informasi ini adalah dapat diakses secara dalam jaringan (daring) melalui internet, sehingga menghindari kehilangan dan kerusakan catatan data. Selain itu fitur-fitur seperti pencatatan detail surat yang terkomputerisasi, pencarian surat dengan cepat berdasarkan kata kunci tertentu, dan penyimpanan salinan surat berupa soft file untuk cadangan arsip dapat memudahkan GMIT GDI dalam memanajemen surat masuk dan surat keluar. Pembuatan sistem informasi ini diharapkan menjadi salah satu bentuk pengabdian kepada masyarakat yang bermanfaat. Adapun metode pengabdian yang diterapkan dalam pengabdian masyarakat ini adalah melalui observasi, perencanaan, dan implementasi.
Efektivitas Pemasaran Tabungan Emas dalam Meningkatkan Minat Berinvestasi Nasabah di Pegadaian Unit Pembantu Cabang Pemogan
Authors: Erfiana Dian , Sariani Ni Luh Putu
Published: March 2024

Pegadaian Gold Savings is a gold balance depository service that facilitates public gold investment, as well as a gold savings product that makes gold investment simple, safe, affordable and reliable. The purpose of this service activity is to increase customer interest in investing in the UPC Pemogan Pawnshop. The method used is observation and evaluation. The results of this activity indicate that the marketing strategy for Gold Savings at UPC Pemogan Pawnshop uses a marketing mix strategy, namely product, price, location, and promotion. Promotions are used with brochures, personal selling, sales promotions by giving free administration fees, and advertisements on Pawnshop TV. The most effective promotion strategy is personal selling. The advice that the author can convey to Pegadaian UPC Pemogan is to provide special sales for Gold Savings products so that it is easier to market Gold Savings products.Â
Pelatihan Peningkatan Ketrampilan Desain dan Layout Buku Elektronik bagi Guru dan Dosen
Authors: Marjuni Aris , Sinaga Daurat , Sugiarto Edi , Rijati Nova
Published: March 2024

Buku, merupakan salah satu bentuk media pembelajaran yang digunakan untuk menyampaikan bahan pembelajaran kepada peserta didik. Profesi guru dan dosen mengharuskan untuk selalu menyusun dan memperbaharui bahan pembelajaran sesuai jenjang dan obyek pembelajarannya. Tugas pembuatan bahan pembelajaran tersebut pada era digital saat ini telah dimudahkan melalui pembuatan buku elektronik atau e-book. Berkembangnya e-book memungkinkan pendidik untuk berimprovisasi menyajikan bahan pembelajaran yang uptodate dan menarik. Penyusun e-book dapat memasukkan konten-konten grafis maupun tekstual yang lebih menarik berbiaya murah dengan teknik desain grafis. Namun demikian, tidak semua pendidik memiliki kemampuan dalam membuat e-book yang menarik. Kegiatan peningkatan ketrampilan teknik desain dan layout pembuatan buku elektronik bagi guru dan dosen ini bertujuan untuk menambah wawasan, pengetahuan, dan ketrampilan teknik desain dan layout pembuatan e-book, terutama bagi guru dan dosen yang belum memiliki pengalaman dalam bidang desain grafis. Pelatihan dilaksanakan secara daring dan diikuti oleh 137 peserta guru dan dosen dari sekolah dan perguruan tinggi. Hasil pelatihan menunjukkan bahwa 93% peserta menyatakan bertambah pengetahuan dan ketrampilan dalam hal teknik desain dan layout pembuatan e-book berdasarkan tugas yang diberikan dari pelatihan.
Pelatihan Literasi Digital Pada Lembaga Kesejahteraan Sosial Anak (LKSA) Aisyiyah Kota Semarang
Authors: Kardianawati Acun - , Winarno Agus , - Suharnawi , Fakhruddin Nada Adila
Published: March 2024

Panti Asuhan Aisyiyah Putri merupakan sebuah lembaga  kesejahteraan sosial anak (LKSA) yang keberadaannya berlokasi di Jl. Srikandi V No. 61, kota Semarang. Panti asuhan melakukan pengasuhan kepada anak asuh yang jumlahnya cukup banyak. Dimana dalam keseharian anak asuh yang ada pada panti asuhan ini juga seringkali mengakses berbagai informasi secara digital. Informasi digital tidak semua yang tersedia dalam berbagai media seringkali tidak selalu memberikan sajian yang benar. Untuk menghindari kesalahan dalam mengakses informasi yang salah perlu adanya pelatihan literasi digital. Luaran pelatihan literasi digital ini adalah memberikan wawasan tentang informasi digital yang harus diakses secara bijak. Saat mendapatkan informasi maka perlu dilakukan penyaringan sebelum informasi tersebut bisa dibagi. Pelatihan dilakukan dengan mengadakan pertemuan secara langsung dengan anak asuh yang di LKSA Aisyiyah Putri Kota Semarang. Dalam pelatihan peserta diberikan wawasan tentang informasi dan bagaimana memvalidasi informasi tersebut dan diberikan pula contoh-contoh penyalahgunaan informasi yang ada pada dunia digital.
Pelatihan Kewirausahaan Untuk Meningkatkan Minat Wirausaha Mahasiswa Jurusan Peternakan Politani Pangkep
Authors: Prayitno Agus Hadi , Hertamawati Rosa Tri , Irwani Nani , Fati Nelzi , Nilawati Nilawati , Masir Ummul , Akhsan Fitriani , Wakano Fahruddin , Abdullahi Alima Bachtiar , Meswari Rusna
Published: March 2024

Pengabdian kepada masyarakat (PKM) ini bertujuan untuk memberikan pelatihan kewirausahaan untuk dapat meningkatkan minat, movitasi, kreativitas, dan juga inovasi bagi mahasiswa Jurusan Peternakan Politeknik Pertanian Negeri Pangkajne Kepulauan. Melalui pelatihan ini, mahasiswa akan diberikan pembekalan dalam menciptakan ide-ide segar yang kreatif dan inovatif dalam dunia wirausaha. Kemampuan berwirausaha yang didapat dari pelatihan ini akan bermanfaat bagi mahasiswa untuk memenuhi kebutuhan pribadi serta memberikan kontribusi kepada masyarakat sekitar dengan membuka lapangan kerja. Kegiatan pengabdian kepada masyarakat ini akan dilakukan melalui pelatihan kewirausahaan, dengan metode ceramah dan sesi tanya jawab sebagai pendekatan utama. Melalui ceramah, peserta mahasiswa akan mendapatkan pengetahuan umum mengenai wirausaha, langkah-langkah memulai usaha, dan cara menemukan peluang dari usaha. Evaluasi dilaksanakan guna mengukur efektivitas pelatihan dalam meningkatkan minat dan semangat mahasiswa untuk terlibat dalam dunia wirausaha. Evaluasi ini juga digunakan untuk mengukur dari pencapaian dalam kegiatan pengabdian kepada masyarakat. Penilaian dilakukan dengan menggunakan kuisioner yang diisi oleh peserta mahasiswa. Hasil evaluasi menunjukkan adanya peningkatan minat mahasiswa Jurusan Peternakan Politani Pangkep untuk terlibat dalam kegiatan wirausaha setelah mereka menerima materi dan motivasi terkait wirausaha.
Peningkatan Gerakan Literasi Sekolah Melalui Pelatihan Pembuatan Mading di SD Muhammadiyah Sambeng
Authors: Santi Fitta Ummaya , Oktariana Detik
Published: March 2024

Majalah Dinding (Mading) merupakan jenis media komunikasi tertulis berisi berbagai informasi dengan menggunakan sebuah papan yang ditempel di dinding. Mading di sekolah menjadi sarana mendapatkan informasi yang sangat praktis. Keberadaan mading di sekolah dapat meningkatkan  kemampuan literasi siswa yang meliputi kemampuan membaca dan menulis. Kegiatan pelatihan ini bertujuan untuk memberikan bekal kepada siswa dalam membuat mading sekolah yang menarik dan informatif. Metode pelaksanaan yaitu diawali dengan sosialiasi pentingnya mading sekolah, cara pembuatan mading, penentuan tema, membuat sketsa mading, pengumpulan karya siswa dan terakhir publikasi mading. Hasil dari pelaksanaan kegiatan ini adalah siswa mampu membuat mading yang menarik dan informatif.  Mading yang telah dibuat dapat meningkatkan kemampuan literasi pada siswa yaitu meliputi kemampuan membaca dan menulis, sehingga program gerakan literasi sekolah dapat mengalami peningkatan.
Peningkatan Pengetahuan Swamedikasi di Kalangan Remaja
Authors: Larasati Niken , Padmasari Siwi , Nova Maria Lisa
Published: March 2024

Swamedikasi merupakan suatu upaya yang dilakukan oleh masyarakat awam untuk mengatasi penyakit atau gejala yang ringan yang dirasakan oleh diri sendiri maupun orang di sekitarnya dengan memilih obat sendiri. Beberapa faktor menjadi pengaruh terhadap perilaku swamedikasi di masyarakat. Pemberian edukasi dan informasi sangat penting untuk dilakukan supaya swamedikasi dapat dilakukan secara tepat. Beberapa penelitian menunjukkan upaya swamedikasi yang tidak rasional seperti tidak mengkonsumsi obat sesuai indikasi, memodifikasi interval dosis yang direkomendasikan, dan menggunakan lebih dari satu jenis obat dalam satu golongan. Penggunaan obat yang tidak rasional tersebut memicu timbulnya potensi kejadian reaksi obat yang merugikan, serta berkurangnya kemanjuran obat. Berdasarkan latar belakang tersebut, maka pemberian edukasi dan informasi terkait swamedikasi sangat penting untuk dilakukan. Peningkatan pengetahuan swamedikasi dapat dilakukan pada masyarakat usia remaja. Kegiatan ini dilaksanakan di SMK Kesehatan Wonosari. Pelaksanaan pengabdian kepada masyarakat dimulai dengan penyusunan materi sebagai instrumen melalui telaah artikel ilmiah untuk menghasilkan informasi yang akurat dan terkini kemudian dipresentasikan kepada siswa SMK Farmasi. Pretes dan postes diberikan untuk menganalisis tingkat pengetahuan siswa tentang swamedikasi. Dari hasil pengisian pretes dan postes menunjukkan adanya peningkatan pengetahuan terhadap swamedikasi setelah pemberian materi pada siswa SMK Kesehatan Wonosari.
Pendampingan Produksi Podcast Youtube Pada Mahasiswa Komunikasi dan Penyiaran Islam Universitas Hasyim Asy'ari Jomban
Authors: Malayati Robi'ah Machtumah , As’ad Muhammad , Anwari -
Published: March 2024

Podcast youtube menjadi salah satu konten media sosial yang banyak ditonton oleh viewer. Proses produksinya yang kompleks menjadi metode alternatif untuk mengasah skill mahasiswa di perguruan tinggi, seperti skill manajemen, public speaking, shooting & editing, dan optimalisasi SEO. Adapun manfaat-manfaat tersebut menjadi solusi permasalahan bagi mahasiswa prodi Komunikasi dan Penyiaran Islam (KPI) Universitas Hasyim Asy’ari (UNHASY) Tebuireng Jombang. Prodi KPI selalu dituntut untuk bisa mengikuti perkembangan komunikasi yang terus berkembang. Sementara itu, di Prodi KPI Unhasy praktek yang up to date semacam itu tidak banyak tereksplorasi dalam kegiatan perkuliahan. Sehingga mahasiswa kurang terwadahi dalam eksplorasi ketrampilan sesuai dengan perkembangan zaman. Untuk itu dilakukan kegiatan pendampingan kepada masyarakat (PkM) dengan menggunakan pendekatan Participatory Action Research (PAR), yaitu suatu pendekatan yang mewajibkan keterlibatan aktif subjek penelitian dalam seluruh proses penelitian. Dalam hal ini, mahasiswa prodi KPI Unhasy sebagai subjek pengabdian turut aktif dalam proses identifikasi, menentukan solusi sampai refleksi. Hasil dari pengabdian menunjukkan ada peningkatan secara kualitatif pada skill mahasiswa seperti kepekaan mengangkat isu menjadi tema acara, skill komunikasi dalam memandu acara, dan skill shooting-editing. Melalui pengabdian ini diharapkan mahasiwa semakin kreatif dan berdampak pada keberhasilan mereka di masa yang akan datang
Pelatihan Public Speaking Untuk Meningkatkan Kemampuan Komunikasi Mahasiswa
Authors: Wahyuddin Wahyuddin , Maharida Maharida , Rijal Ahmad
Published: March 2024

Kegiatan ini dilatar belakangi oleh masalah yang dihadapi mahasiswa dalam bekomunikasi. Masih dimukan keluhan dari dosen terkait cara komunikasi mahasiswa yang kurang efektif, baik dalam proses pembelajaran maupun dalam berkomunikasi sosial dalam pergaulan. Untuk mengatasi masalah tersebut, sehingga diberikan solusi berupa pelatihan public speaking untuk meningkatkan kemampuan komunikasi mahasiswa. Kegiatan ini dilakukan dengan metode seminar dan simulasi. Kegiatan ini diawali dengan perencanaan dan analisis masalah, perencanaan pemberian solusi, pelaksanaan kegiatan, dan evaluasi, laporan,dan publikasi. Kegiatan ini dilaksanan di Universitas Muhammadiyah Makassar dengan melibatkan mahasiswa Prodi Manajemen dan PGSD. Teknik pengumpulan data melalui wawancara, angket, dan teknik analisis data deskriptif. Hasil kegiatan menyimpulkan bahwa pelatihan public speaking dapat meningkatkan kemampuan dan keterampilan mahasiswa dalam berkomunikasi efektif serta kemampuan berbicara di depan umum. Kegiatan tersebut juga terlaksana efektif dengan indikator bahwa pemahaman peserta terkait materi mencapai 83,33%; tingkat kepuasan peserta mencapai 91,67%; penyampaiaan materi yang jelas mencapai 91,67%; kesesaian materi dengan topik kegiatan mencapai 100%; dan kegiatan pelatihan dapat memberi solusi dari masalah public speaking mencapai 91,67%; dan kepuasan terhadap fasilitas mencapai 91,67%. Hasil ini memperkuat penelitian sebelumnya bahwa pelatihan public speaking dapat meningkatkan kemampuan komunikasi. Sehingga keterampilan public speaking perlu dimiliki oleh setiap mahasiswa sebagai calon tenaga kerja professional.
Multimedia educativa para el desarrollo de habilidades lógico-matemáticas en niños de inicial II
Authors: Fernández Marín Miguel Ángel , Nacimba Quinga Ana Cecilia , Gutiérrez Rodríguez Fidel Ángel , González Tolmo Débora
Published: March 2024

The preparation of a multimedia suitable for the end user allowed to obtain a product that meets the needs of the Child Development Centers of Amaguaña, in the Rumiñahui province of Pichincha, Ecuador. The “Pollitos Felices” Comprehensive Educational Center was considered as a pilot plan for the same project, in which multimedia was experienced, consecutively it is put into consideration in other centers where the functions and learning abilities of children were evaluated in a general way. The following tools were used to prepare the multimedia: Jclic 3.0 for multimedia design, Mysql 5.5.8 was used as the database manager. It was used for image design and sound editing Fireworks 8.0.0.7 and Audacity 2.1.2 respectively. The black box testing technique is used in order to assess the relevant validations in the interface, the result obtained was good. To validate the proposed solution according to expert criteria, once tested in the different educational centers, a survey is carried out.
Diagnóstico de habilidades socioemocionales en universitarios hacia la tutoría
Authors: Aguilar Islas Karla Gabriela , Moreno Tapia Javier , Torquemada Alma Delia
Published: March 2024

This report describes the research work that has had the purpose of characterizing the socio-emotional competencies that predominate in a group of university students of the Education Sciences career, where one of the main aspirations is to be a teacher. For them, a Socio-Emotional Skills scale was constructed, which allowed us to inquire about the teaching practice and its relationship with the socio-emotional skills they identify. The instruments were applied to a population selected in a non-probabilistic way for convenience to teachers in training. In both scales, it is evident that the participants have developed socio-emotional competencies; However, there is a need to go deeper into the reflexive aspect and the analysis capacity to promote more personal tools when it comes to educational practice.
Studi Pembelajaran Berbasis Teknologi Di Abad 21 Pada Mata Kuliah Desain Grafis Pada Perguruan Tinggi Jurusan Teknik Informatika
Authors: Simeru Arden , Lubis Arina Luthfini
Published: March 2024

Abad 21 atau yang lebih dikenal sebagai zaman modern serta zaman era revolusi industri 4.0 yang mengharuskan tiap-tiap kegiatan yang dilaksanakan mampu memanfaatkan penggunaan mesin atau teknologi otomasi. Terutama teknologi yang paling diharapkan mampu untuk menjadi sebuah keutamaan dalam pemanfaatannya itu sendiri ialah teknologi informasi dan komunikasi. Terlebih jika kita mengacu dan melihat kepada tahun 2019 akhir dimana sebuah virus COVID-19 melanda dunia dan mengharuskan tiap-tiap pekerjaan dilaksanakan dirumah (WFH) untuk mengurangi kontak fisik dan penyebaran virus, dengan memanfaatkan Teknologi Informasi dan Komunikasi sebagai wadah komunikasi dan penyebaran pemberitahuan dan informasi yang diperlukan. Kemudian untuk matakuliah desain grafis yang mana mahasiswa harus mampu mencobakan secara langsung tata cara membuat sebuah desain dengan memanfaatkan tools-tools serta software yang ada, maka pemanfaatan teknologi informasi ini harus lebih dikembangkan dan dimanfaatkan secara maksimal agar nantinya kompetensi yang diharapkan kepada mahasiswa dapat tercapai. Artikel ini menggunakan metode studi literatur untuk melihat bagaimana pemanfaatan dan optimalisasi dari teknologi informasi baik pada mata kuliah desain grafis maupun mata kuliah pada umumnya.
Analisis Pemanfaatan Platform TikTok sebagai Media Aktualisasi Diri Peserta Didik
Authors: Sofa Nurul Aeni , Annaafi’atsaani Irbasabila , Ihsanuddin Ahmad Noor , Anbiya Bakti Fatwa
Published: March 2024

Times are getting more advanced as well as more and more social media available as information and communication services. The social media application TikTok is in great demand by all groups, especially teenagers or students. The social media application TikTok can be used in various fields. In the TikTok application, everything has been presented in audio-visual form. With TikTok, students can carry out learning. Not only for learning, but TikTok is a tool or means of self-actualization where students can express and develop their potential in cyberspace to achieve their desires. The purpose of this writing is to find out how students use and utilize social media TikTok as a means of self-actualization. The method used in this research is a case study. Where data collection is carried out by observing an account on the TikTok application. Namely the tiktok account from @Zulkar_na which has 168.7 thousand followers, and 8.5 million likes, and the video with the most viewers, namely 17.6 million viewers. From the results of this study, it can be obtained that students use TikTok social media to express themselves in cyberspace as well as to obtain and share various information because TikTok social media is a comfort zone for all people to make it easier to get everything they want.
Towards a childist theory of democratic dannelse: An argument for the radical potential of more age-inclusive scholarly imagination
Authors:   ,   Aarhus University, Hedegaard Maria Louise Larsen
Published: March 2024

This dissertation uses the case of the Danish state school to study the democratic aspect of education – in Danish referred to as ‘demokratisk dannelse’. Drawing on a poststructuralist framework and the concept of childism, the dissertation draws attention to how a historically ingrained deficit-perception of the child underlies democratic dannelse in both theory and practice. This is fundamentally a marginalizing and colonizing starting point in that it involves the claim that the child cannot speak as a political subject before it has learned to speak in the ‘right’ (presumed democratic) way. The dissertation draws together two different types of analysis (one focused on discourse, the other on practices in schools) through multiple conceptual lenses and discusses how the lens of childism can potentially widen the epistemological space through which the democratic aspect of education can be understood. Rather than focusing on ‘preparing’ children and young people for (future) democratic life, childism allows for concepts like ‘voice’, ‘participation’, ‘rights’, ‘politics’ and ‘democracy’ etc. to be reimagined in more age-inclusive ways. From a childist perspective, the democratic task of education becomes that of supporting and responding to the student as the political subject it already is. This, the dissertation argues, has a radical and far more democratic potential.
”Der, hvor teori blev til praksis for mig”
Authors: Friis Andersen Marianne , Skovgaard Thomas
Published: March 2024

Lærerne i den danske folkeskole skal tage højde for eksplicitte lovkrav omhandlende inklusion og bevægelse i undervisningen. Det er afgørende, at lærere arbejder bevidst med et inkluderende sigte, når de gør brug af bevægelse i undervisningen. Artiklen belyser, hvordan en bestemt gruppe grundskolelærere arbejder med at skabe rammer for en inkluderende bevægelsespraksis. Artiklens empiriske udgangspunkt er et konkret aktionslæringsforløb forankret i Karl Weicks udredninger af forudsætninger for produktiv meningsskabelse. På baggrund af vores analytiske fund påviser vi, at aktionslæringsforløbet og Weicks meningsskabelsestilgang hjælper lærerne med at forankre og skabe mening og retning i arbejdet med inkluderende bevægelsesaktiviteter i praksis.
Sicherheitsdiskurse aus linguistischer Perspektive. Annelie Schmidt (2018): „Sicherheit“ im öffentlichen Sprachgebrauch. Eine diskurslinguistische Analyse. Berlin, Boston: De Gruyter, 386 S.
Authors: Trojanowski Jędrzej
Published: March 2024

Eś handelt sich um eine Rezension des folgenden Buches: Annelie Schmidt (2018): „Sicherheit“ im öffentlichen Sprachgebrauch. Eine diskurslinguistische Analyse. Berlin, Boston: De Gruyter, 386 S.
Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse
Authors: Muroňová Jana , Kherraf Zine Eddine , Giordani Elsa , Lambert Emeline , Eckert Simon , Cazin Caroline , Amiri-Yekta Amir , Court Magali , Chevalier Geneviève , Martinez Guillaume , Neirijnck Yasmine , Kühne Francoise , Wehrli Lydia , Klena Nikolai , Hamel Virginie , De Macedo Lisa , Escoffier Jessica , Guichard Paul , Coutton Charles , Mustapha Selima Fourati Ben , Kharouf Mahmoud , Bouin Anne-Pacale , Zouari Raoudha , Thierry-Mieg Nicolas , Nef Serge , Geimer Stefan , Loeuillet Corinne , Ray Pierre F , Arnoult Christophe
Published: March 2024

From a cohort of 167 infertile patients suffering from multiple morphological abnormalities of the flagellum (MMAF), pathogenic bi-allelic mutations were identified in the CCDC146 gene. In somatic cells, CCDC146 is located at the centrosome and at multiple microtubule-related organelles during mitotic division, suggesting that it is a microtubule-associated protein (MAP). To decipher the molecular pathogenesis of infertility associated with CCDC146 mutations, a Ccdc146 knock-out (KO) mouse line was created. KO male mice were infertile, and sperm exhibited a phenotype identical to CCDC146 mutated patients. CCDC146 expression starts during late spermiogenesis. In the spermatozoon, the protein is conserved but is not localized to centrioles, unlike in somatic cells, rather it is present in the axoneme at the level of microtubule doublets. Expansion microscopy associated with the use of the detergent sarkosyl to solubilize microtubule doublets suggests that the protein may be a microtubule inner protein (MIP). At the subcellular level, the absence of CCDC146 impacted all microtubule-based organelles such as the manchette, the head–tail coupling apparatus (HTCA), and the axoneme. Through this study, a new genetic cause of infertility and a new factor in the formation and/or structure of the sperm axoneme were characterized.
Distinct T Cell Receptor (TCR) gene segment usage and MHC-restriction between foetal and adult thymus
Authors: Rowell Jasmine , Lau Ching-In , Ross Susan , Yanez Diana C. , Chain Benny , Crompton Tessa
Published: March 2024

Here we sequenced rearranged TCRβ and TCRα chain sequences in CD4+CD8+ double positive (DP), CD4+CD8-single positive (SP4) and CD4-CD8+ (SP8) thymocyte populations from the foetus and young adult mouse. We found that life-stage had a greater impact on TCRβ and TCRα gene segment usage than cell-type. Foetal repertoires showed bias towards 3’TRAV and 5’TRAJ rearrangements in all populations, whereas adult repertoires used more 5’TRAV gene segments, suggesting that progressive TCRα rearrangements occur less frequently in foetal DP cells. When we synchronised young adult DP thymocyte differentiation by hydrocortisone treatment the new recovering DP thymocyte population showed more foetal-like 3’TRAV and 5’TRAJ gene segment usage. In foetus we identified less influence of MHC-restriction on β-chain combinatorial VxJ usage and predicted α and β CDR1xCDR2 usage in S P compared to adult, indicating weaker impact of MHC-restriction on the foetal TCR repertoire. The foetal TCRβ repertoire was less diverse, less evenly distributed, with fewer non-template insertions, and all foetal populations contained more clonotypic expansions than adult. The differences between the foetal and adult thymus TCR repertoires are consistent with the foetal thymus producing αβT-cells with properties and functions that are distinct from adult T-cells, and more innate-like: their repertoire is less governed by MHC-restriction, with preference for particular gene segment usage, less diverse with more clonotypic expansions, and more closely encoded by genomic sequence.
PKA regulation of neuronal function requires the dissociation of catalytic subunits from regulatory subunits
Authors: Xiong Weihong , Qin Maozhen , Zhong Haining
Published: March 2024

Protein kinase A (PKA) plays essential roles in diverse cellular functions. However, the spatiotemporal dynamics of endogenous PKA upon activation remain debated. The classical model predicts that PKA catalytic subunits dissociate from regulatory subunits in the presence of cAMP, whereas a second model proposes that catalytic subunits remain associated with regulatory subunits following physiological activation. Here, we report that different PKA subtypes, as defined by the regulatory subunit, exhibit distinct subcellular localization at rest in CA1 neurons of cultured hippocampal slices. Nevertheless, when all tested PKA subtypes are activated by norepinephrine, presumably via the β-adrenergic receptor, catalytic subunits translocate to dendritic spines but regulatory subunits remain unmoved. These differential spatial dynamics between the subunits indicate that at least a significant fraction of PKA dissociates. Furthermore, PKA-dependent regulation of synaptic plasticity and transmission can be supported only by wildtype, dissociable PKA, but not by inseparable PKA. These results indicate that endogenous PKA regulatory and catalytic subunits dissociate to achieve PKA function in neurons.
PKA regulation of neuronal function requires the dissociation of catalytic subunits from regulatory subunits
Authors: Xiong Wei-Hong , Qin Maozhen , Zhong Haining
Published: March 2024

Protein kinase A (PKA) plays essential roles in diverse cellular functions. However, the spatiotemporal dynamics of endogenous PKA upon activation remain debated. The classical model predicts that PKA catalytic subunits dissociate from regulatory subunits in the presence of cAMP, whereas a second model proposes that catalytic subunits remain associated with regulatory subunits following physiological activation. Here we report that different PKA subtypes, as defined by the regulatory subunit, exhibit distinct subcellular localization at rest in CA1 neurons of cultured hippocampal slices. Nevertheless, when all tested PKA subtypes are activated by norepinephrine, presumably via the β-adrenergic receptor, catalytic subunits translocate to dendritic spines but regulatory subunits remain unmoved. These differential spatial dynamics between the subunits indicate that at least a significant fraction of PKA dissociates. Furthermore, PKA-dependent regulation of synaptic plasticity and transmission can be supported only by wildtype, dissociable PKA, but not by inseparable PKA. These results indicate that endogenous PKA regulatory and catalytic subunits dissociate to achieve PKA function in neurons.
Accelerated signal propagation speed in human neocortical microcircuits
Authors: Oláh Gáspár , Lákovics Rajmund , Shapira Sapir , Leibner Yoni , Szűcs Attila , Csajbók Éva Adrienn , Barzó Pál , Molnár Gábor , Segev Idan , Tamás Gábor
Published: March 2024

Human-specific cognitive abilities depend on information processing in the cerebral cortex, where neurons are significantly larger and sparser compared to rodents. We found that, in synaptically-connected layer 2/3 pyramidal cells (L2/3 PCs), soma-to-soma signal propagation delay is similar in humans and rodents. Thus, to compensate for the increase in neurons’ size, membrane potential changes must propagate faster in human axons and/or dendrites. Dual somato-dendritic and somato-axonal patch recordings show that action potentials (APs) propagation speed is similar in human and rat axons, but the forward propagation of the EPSPs and the back-propagating APs are ∼ 26 and 47% faster in human dendrites respectively. Faithful biophysical models of human and rat L2/3 PCs, combined with pharmacological manipulations of membrane properties, showed both the larger diameter of the apical dendrite and the larger conductance load imposed by the basal tree in human, combined with differences in cable properties, underlie the accelerated signal propagation in human cortical circuits.
Impaired myofibroblast proliferation is a central feature of pathologic post-natal alveolar simplification
Authors: Khan Imran S , Molina Christopher , Ren Xin , Auyeung Vincent C , Cohen Max , Tsukui Tatsuya , Atakilit Amha , Sheppard Dean
Published: March 2024

Premature infants with bronchopulmonary dysplasia (BPD) have impaired alveolar gas exchange due to alveolar simplification and dysmorphic pulmonary vasculature. Advances in clinical care have improved survival for infants with BPD, but the overall incidence of BPD remains unchanged because we lack specific therapies to prevent this disease. Recent work has suggested a role for increased transforming growth factor-beta (TGFβ) signaling and myofibroblast populations in BPD pathogenesis, but the functional significance of each remains unclear. Here, we utilize multiple murine models of alveolar simplification and comparative single-cell RNA sequencing to identify shared mechanisms that could contribute to BPD pathogenesis. Single-cell RNA sequencing reveals a profound loss of myofibroblasts in two models of BPD and identifies gene expression signatures of increased TGFβ signaling, cell cycle arrest, and impaired proliferation in myofibroblasts. Using pharmacologic and genetic approaches, we find no evidence that increased TGFβ signaling in the lung mesenchyme contributes to alveolar simplification. In contrast, this is likely a failed compensatory response, since none of our approaches to inhibit TGFβ signaling protect mice from alveolar simplification due to hyperoxia while several make simplification worse. In contrast, we find that impaired myofibroblast proliferation is a central feature in several murine models of BPD, and we show that inhibiting myofibroblast proliferation is sufficient to cause pathologic alveolar simplification. Our results underscore the importance of impaired myofibroblast proliferation as a central feature of alveolar simplification and suggest that efforts to reverse this process could have therapeutic value in BPD.
Impaired Myofibroblast Proliferation is a Central Feature of Pathologic Post-Natal Alveolar Simplification
Authors: Khan Imran S. , Molina Christopher , Ren Xin , Auyeung Vincent C. , Cohen Max , Tsukui Tatsuya , Atakilit Amha , Sheppard Dean
Published: March 2024

Premature infants with bronchopulmonary dysplasia (BPD) have impaired alveolar gas exchange due to alveolar simplification and dysmorphic pulmonary vasculature. Advances in clinical care have improved survival for infants with BPD, but the overall incidence of BPD remains unchanged because we lack specific therapies to prevent this disease. Recent work has suggested a role for increased transforming growth factor-beta (TGFβ) signaling and myofibroblast populations in BPD pathogenesis, but the functional significance of each remains unclear. Here, we utilize multiple murine models of alveolar simplification and comparative single-cell RNA sequencing to identify shared mechanisms that could contribute to BPD pathogenesis. Single-cell RNA sequencing reveals a profound loss of myofibroblasts in two models of BPD and identifies gene expression signatures of increased TGFβ signaling, cell cycle arrest, and impaired proliferation in myofibroblasts. Using pharmacologic and genetic approaches, we find no evidence that increased TGFβ signaling in the lung mesenchyme contributes to alveolar simplification. In contrast, this is likely a failed compensatory response, since none of our approaches to inhibit TGFb signaling protect mice from alveolar simplification due to hyperoxia while several make simplification worse. In contrast, we find that impaired myofibroblast proliferation is a central feature in several murine models of BPD, and we show that inhibiting myofibroblast proliferation is sufficient to cause pathologic alveolar simplification. Our results underscore the importance of impaired myofibroblast proliferation as a central feature of alveolar simplification and suggest that efforts to reverse this process could have therapeutic value in BPD.
Diverging roles of TRPV1 and TRPM2 in warm-temperature detection
Authors: El Hay Muad Y. Abd , Kamm Gretel B. , Tlaie Alejandro , Siemens Jan
Published: March 2024

The accurate perception of innocuous temperatures, particularly those experienced as pleasantly warm, is essential for achieving thermal comfort and maintaining thermoregulatory balance. Warm-sensitive neurons (WSN) innervating the skin play a central role in non-painful warmth detection. The TRP ion channels TRPV1 and TRPM2 have been suggested as sensors of warm temperature in WSNs. However, the precise contribution of these channels to the process of warmth detection is not fully understood.A significant challenge in analysing WSNs lies in their scarcity: fewer than 10 % of sensory neurons in the rodent dorsal root ganglion (DRG) respond to innocuous warm temperatures. In this study, we examined >20,000 cultured mouse DRG neurons using calcium imaging and discovered distinct contributions of TRPV1 and TRPM2 to warm-temperature sensitivity. TRPV1 and TRPM2 affect the abundance of WSNs, with TRPV1 mediating the rapid, dynamic response to warmth.By carefully tracking animal movement in a whole-body thermal preference paradigm, we observe that these cellular differences correlate with nuanced thermal behaviours. Utilizing a driftdiffusion model to quantitatively analyse the decision-making process of animals exposed to different environmental temperatures, we found that: TRPV1 primarily impairs the precision of evidence accumulation, whereas TRPM2 significantly increases the total duration of exposure to uncomfortably warm environments.Our findings provide valuable insights into the distinct molecular responses to warmth stimuli, and underpin the subtle aspects of thermal decision-making when encountering minor temperature variations.
Projeto maratona infantil: um olhar reflexivo sobre a vivência corporal e a prática significativa
Authors: Pantoja Bianca de Fátima Fonseca Jardim , Cardoso Danielle da Costa , Pessoa Neta Francisca da Silva , Bezerra Inoani Lima , Chaves Ligia Gizely dos Santos , De Barros Natielle Aurélia da Conceição , Dos Santos Rodolfo Aurélio Fonseca , Cabral Thayane Christine Franco
Published: March 2024

O objetivo desse estudo foi compartilhar experiências e refletir a respeito do Projeto da Maratona Infantil realizado pela equipe de Educação Física em parceria com a equipe pedagógica do Colégio Tenente Rêgo Barros sobre a importância dos jogos e das brincadeiras para o desenvolvimento integral dos alunos. Destaca-se que o referencial teórico adotado na pesquisa, contou com as contribuições de renomados autores do campo da educação tais como, Wiertsema(1998), Brougére(1010), Ausubel (1963,1968) e Moreira (2010). O presente artigo teve como principal objetivo a descrição das práticas pedagógicas desenvolvidas por meio do Projeto da Maratona Infantil, na qual teve como eixo de trabalho algumas temáticas cruciais para a formação discente tais como: saúde, cidadania, ética, e a importância do brincar e as contribuições das interações e das brincadeiras. O artigo está apresentado da seguinte forma, primeiramente foi apresentado o projeto da maratona Infantil, em seguida, o público destinado, depois foi abordada a importância da ressignificação das práticas esportivas nas aulas de Educação Física.Posteriormente, foi apresentado o objetivo principal do projeto, a concepção de sua criação, o contexto social do brincar, das brincadeiras e dos jogos. Além disso, foi abordado a questão da livre escolha por parte das crianças durante o processo das brincadeiras. Em seguida descreve como ocorreu a “Maratona infantil”, depois destaca a importante contribuição do professor de Educação física e apresenta uma breve avaliação do desenvolvimento do projeto da “Maratona infantil” em relação a interação entre as crianças durante os jogos e finaliza retomando o papel do profissional de Educação física para com seus alunos.
Review of The Sufi Saint of Jam: History, Religion, and Politics of a Sunni Shrine in Shiʿi Iran
Authors: Haider Najam
Published: March 2024

The Sufi Saint of Jam: History, Religion, and Politics of a Sunni Shrine in Shiʿi Iran. By Shivan MahendraraJah. Cambridge Studies in Islamic Civilization. Cambridge: Cambridge University Press. Pp. xx + 270, illus. $99.99 (cloth); $80 (ebook).
Review of The Body in Arabic Love Poetry: The ʿUdhri Tradition
Authors: Blankinship Kevin
Published: March 2024

The Body in Arabic Love Poetry: The ʿUdhri Tradition. By Jokha Alharthi. Edinburgh: Edinburgh University Press, 2021. Pp. xviii + 270. $29.95 (paper).
Review of The Making of a New Rural Order in South China, vol. 2: Merchants, Markets, and Lineages, 1500– 1700
Authors: Zurndorfer Harriet
Published: March 2024

The Making of a New Rural Order in South China, vol. 2: Merchants, Markets, and Lineages, 1500– 1700. By Joseph P. McDermott. Cambridge: Cambridgr University Press, 2020. Pp. xii + 468. $139 (cloth); $45 (paper).
Review of Mesopomatian Eye Disease Texts: The Nineveh Treatise
Authors: Scurlock JoAnn
Published: March 2024

Mesopomatian Eye Disease Texts: The Nineveh Treatise. By Markham J. Geller and Strahil V. Panayotov. Die Babylonisch-Assyrische Medizin in Texten und Untersuchungen, vol. 10. Berlin: de Gruyter, 2020. Pp. xii + 454, illus. $181.99.
Insight into Stenotrophomonas maltophilia Infections in a Tertiary Care Teaching Hospital in Western India and Review of Literature: A Retrospective Observational Study
Authors: Bacchani Daisy , Rajni Ekadashi , Kataria Shaveta , Sharma Chinkle , Sharma Richa , Garg Vishnu Kumar
Published: March 2024

Introduction: Stenotrophomonas maltophilia (S. maltophilia) is a ubiquitous and opportunistic pathogen of growing importance. This gram-negative, non fermenter is widely distributed in moist hospital environments. It is intrinsically resistant to a number of antibiotics, making it a challenge both for the clinician and the microbiologist. Very sparse data is available from Western India regarding this emerging pathogen. Aim: To determine the prevalence and spectrum of infections caused by S. maltophilia and to provide an overview of associated co-morbidities, antibiotic susceptibility pattern of these isolates, and clinical outcomes. Materials and Methods: This retrospective observational study was carried out in a tertiary care private hospital (Mahatma Gandhi Hospital) in Jaipur, Rajasthan, India over a period of one year (July 2021-June 2022). A total of 11,170 samples were received in the microbiology laboratory for bacterial culture and susceptibility testing during the study period and processed as per standard protocols. Only one isolate per patient was included for the purpose of the study. Culture identification and antibiotic susceptibility testing was done using the VITEK-2 automated system. Data regarding patients’ demographic profile, epidemiological profile, baseline characteristics, comorbidities, laboratory findings, and clinical outcome were tabulated in an Excel worksheet and analysed. All statistical analysis was done using the Software Statistical Package for the Social Sciences (SPSS) version 20.0. Results: Fourteen patients were found to have S. maltophilia infection during the study period. The majority of patients had respiratory tract infection and bacteraemia. All isolates were from inpatients, more than two-thirds being from the Intensive Care Unit (ICU). A high level of susceptibility was seen to routinely recommended drugs, with 100%, 93% and 79% being susceptible to minocycline, levofloxacin and co-trimoxazole, respectively. All patients (except one) were successfully managed and discharged. Conclusion: S. maltophilia is an emerging opportunistic pathogen and is associated with a plethora of clinical conditions. Early and accurate diagnosis by embracing automation in microbiology laboratories is essential to identify this pathogen. S. maltophilia infections have a favourable outcome when diagnosed and treated timely
Emergency Bilateral Internal Iliac Artery Ligation in Antepartum Haemorrhage with Complete Placenta Previa and Placenta Accreta at Previous Caesarean Scar Site: A Case Report
Authors: Salvi Pankaj , Ponde Sanjay , Gaikwad Vidya , Aramandla Sneha
Published: March 2024

Implantation and placentation at the normal site are critical for a successful pregnancy. Many complications associated with pregnancy, which manifest late in pregnancy, such as preeclampsia and preterm labour, have been reported to have origins early during pregnancy with abnormalities in implantation and placental development. Placental abnormalities result from impaired embedding of the placenta in the endometrium, encompassing a wide range of placental pathologies associated with high maternal morbidity and mortality. Pregnancy-related complications such as Postpartum Haemorrhage (PPH) and hysterectomy have been closely linked to the Placenta Accreta Spectrum (PAS). PAS refers to the aberrant and invasive implantation of the placenta into the myometrium. Invasiveness in placenta accreta is marginal, followed by placenta increta (partial), placenta percreta (total), and placenta previa (covering the cervix). Here, the authors present a unique case report of an antenatal woman with antepartum haemorrhage, placenta previa, and placenta accreta at the previous Lower Segment Caesarean Section (LSCS) scar site, with massive PPH at 35 weeks, who benefited from an emergency LSCS with bilateral uterine and internal iliac artery ligation procedure, resulting in a life-saving outcome. The most common risk factors for PAS include prior caesarean section and curettage. The adhered placenta can lead to pelvic bleeding and necessitate an emergency hysterectomy. Therefore, it poses unique diagnostic and treatment issues, with the majority of cases requiring preterm termination of pregnancy.
Patriarch Regression in Social Media
Authors: Rewindinar .
Published: March 2024

Patriarchal culture continues to grow in modernity. Women’s struggles have been applied in various aspects and the digital space has now become a social space to break down the male hegemony. Bourdieu's habitus perspective was applied in this study aiming to see how social media becomes a practice environment for the reaffirmation of women as a class that wants to dispose of the social structures. In this case, virtual ethnographic method was applied from January 2022 to December 2022 to analyze the content of female Instagram users as wives and mothers. Social media has become a field in the habitus process. Field is a social space to produce and distribute meaning from the modern women who have individual, family, and social activities. In habitus process, the production and distribution of meaning is the cultural capital of the social media users. There has been patriarchal regression in social media.
Seasonal Swings and Graphical Tale of Growth and Productivity of Wheat in Gujarat State in Comparison with National Market (India)
Authors: Joyal Damor , Chandrakar M. R.
Published: March 2024

This study comprehensively analyzes the growth and variability in the area, production, and productivity of wheat, a staple food grain in Gujarat state, India, for the period 2001-2022. Wheat holds significant importance in India's agricultural landscape, being one of the staple crops vital for food security. Gujarat, known for its diverse agro-climatic conditions, plays a pivotal role in contributing to the nation's wheat production. Understanding the seasonal dynamics, growth patterns, and productivity trends of wheat in Gujarat which is the broader national market provides valuable insights into the agricultural dynamics of the region. Utilizing exponential fitting and statistical regression techniques, the research presents compound growth rates for India and Gujarat, revealing significant positive correlations between wheat cultivation area, production, and productivity. Graphical representations depict trends and fluctuations, highlighting periods of deviation from trend lines. Instability analyses for India and Gujarat shed light on the consistency and fluctuations in wheat cultivation, production, and productivity. Additionally, the study explores seasonal variations in wheat prices across markets in Gujarat, providing insights into intra-year price cycles and coefficient variations. The findings contribute valuable insights into the dynamics of wheat agriculture in Gujarat, offering implications for policy and agricultural practices.