bluuebunny/crossref_metadata_2025 huggingface dataset:
ПАРАМЕТРЫ ГОМЕОСТАЗА ХИМИЧЕСКИХ ЭЛЕМЕНТОВ В БИОЛОГИЧЕСКИХ ОБРАЗЦАХ ПАЦИЕНТОВ, ЗАВЕРШИВШИХ ТЕРАПИЮ ПО ПОВОДУ ЗЛОКАЧЕСТВЕННЫХ НОВООБРАЗО-ВАНИЙ
Authors:   Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава Российской Федерации, Жуковская Е.В. , Нор А.А. ,   Первый Московский государственный медицинский университет имени И.М. Сеченова, Карелин А.Ф. ,   Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава Российской Федерации
Published: July 2021

Изучение метаболизма у детей с различными злокачественными новообразованиями обусловлено их высокой социальной значимостью, растущей заболеваемостью во всех возрастных группах. Предполагается возможная роль биоэлементов в канцерогенезе, вследствие чего увеличивается число исследований в области микроэлементологии. Целью настоящего пилотного исследования является определение содержания макро- и микроэлементов в биологических пробах пациентов, излеченных от злокачественных новообразований. Исследование выполнено в лечебно-реабилитационном научном центре «Русское поле». Все пациенты находились в ремиссии острого лимфобластного лейкоза и лимфом, коды заболеваний по МКБ: С 91 и С 81-84. Были сформированы исследовательская и контрольная группы. Выявлены отклонения в содержании большинства тестируемых микро- и макроэлементов. Наиболее значимым является профицит отдельных эссенциальных микроэлементов и макроэлементов калия, кальция, фосфора, цинка, железа, меди у пациентов, завершивших противоопухолевую терапию по сравнению с группой контроля. Вместе с тем имеется дефицит такого жизненно важного микроэлемента, как селен.
Derechos Fundamentales, el Covid-19 y la Afectación de Derechos a los Grupos en Situación de Vulnerabilidad. Los Adultos Mayores
Authors: Mendes Lucivania Dias , Rojas Gerardo Bernales
Published: July 2021

La pandemia generada por el Covid-19, ha producido efectos globales no vistos en estos tiempos, y no solo en la salud, sino que, en todos los ámbitos de la vida, lo que ha llevado a que los gobiernos tomen decisiones de todo tipo y no solo sanitarias para disminuir la expansión de la pandemia y sus secuelas. Para ello los Estados se valen de las herramientas constitucionales que les permiten restringir el ejercicio de algunos derechos fundamentales, para alcanzar su objetivo. Sin embargo, estos “remedios” provocan efectos segundarios severos, en los llamados “grupos en situación de vulnerabilidad”[3]. En el presente artículo pretendemos analizar como en Brasil y Chile, las decisiones de la autoridad, si bien miran al bien común, tienen la contradicción de afectar particularmente los miembros de estos grupos, focalizando nuestro trabajo en la situación de los adultos mayores, dados ciertos efectos concretos que se radican en este segmento de la sociedad.
A Proteção da Diversidade do Patrimônio Cultural da Filosofia de Cooperação Social do Nhandereko e do Teko Porã como Expressão do Bem-Viver
Authors: Brasil Deilton Ribeiro
Published: July 2021

Esta pesquisa tem como objetivo analisar a filosofia da cooperação social do Nhandereko e do Teko Porã do bem viver como concepção de interculturalidade no tratamento da diversidade cultural e o direito do povo guarani ter em sua cultura a marca de sua própria existência. A hipótese levantada é no sentido de se averiguar sobre a possibilidade desse diálogo no plano interno e internacional com o rol de direitos culturais reconhecidos na Constituição Federal de 1988. O texto propõe, fazendo-se uso do método indutivo e de pesquisa bibliográfica, uma nova concepção de interculturalidade no tratamento da diversidade cultural que pode ser caracterizada como o interrelacionamento entre culturas em situação de igualdade em um constante processo de aprendizagem e comunicação entre pessoas, valores e tradições.
Soberania versus Fraternidade
Authors: Azambuja Carmen Luiza Dias de
Published: July 2021

A Lei somente é obedecida se aceita pela população. O Estado não pode mais impor direitos fundamentais como meras regras ante a aplicação de sua Soberania, forçando sua obediência. Igualdade e Liberdade dependem de sua implementação ativa pelo Estado. Com isso, somente a partir da consideração de um direito fundamental como a paz como transcendente ao Estado, quando todos os Estados e todos os cidadãos comungarem essa noção, haverá sua condição interna e externa. Então, os direitos fundamentais como a fraternidade/paz, como princípios, serão aceitos e verdadeiros em efetividade. Assim, fazer aos outros o que gostaríamos que nos fosse feito terá vigência prática. Esta é a essência da Fraternidade, como direito fundamental à Paz de 5ª geração.
Direitos Humanos e Retóricas Canibais
Authors: Marsillac Narbal de
Published: July 2021

Se a universalização dos direitos humanos representa para alguns uma vitória gloriosa da cultura jurídica do século passado, para outros, entretanto, espelha o fracasso e está vinculada aos últimos suspiros de um tipo de racionalidade jurídica que buscara, ainda que de forma bem intencionada, a ampliação máxima do alcance desses direitos pela correlata busca por fundamentos últimos e definitivos. A hipótese que foi aqui levantada é que sem perceber e se deixando guiar por critérios morais supostamente universais e, portanto, arretóricos, desprestigiou-se o diálogo intercultural e se desconsiderou o que há de único e endêmico nas culturas minoritárias, legitimando a exclusão ou a inclusão subalterna. Canibalizando, assim, através de retóricas com pretensões apodíticas (retóricas arretóricas), as outras inúmeras gramáticas da dignidade que ainda vigem no mundo plural que habitamos. O objetivo aqui é, portanto, denunciar, pelo método da análise retórica, esse processo de canibalização, subsunção e menosprezo pela compreensão de mundo alheia à que subjaz por detrás das teorias universais de direitos humanos.
Migrações internacionais contemporâneas e crise de refugiados no arco noroeste do Brasil: o caso do acolhimento de venezuelanos pelo estado de Roraima (2018–2019) /Contemporary international migration and refugee crisis in the northwestern arch of Brazil
Authors: Sarmiento da Silva Érica , Rodrigues Fernando da Silva
Published: July 2021

Este artigo tem por objetivo analisar o fluxo de migrações internacionais, no contexto da crise de refugiados venezuelanos no arco noroeste do Brasil, no estado de Roraima. Mais do que a simples entrada de venezuelanos, a investigação analisa a capacidade do Brasil em acolher os pedidos de asilo que recebeu nos anos de 2018 e 2019, bem como suas políticas e ações desenvolvidas. Diante desta conjuntura, o Estado brasileiro adotou medidas que demandaram solidariedade, união e trabalho interagências estatais e não estatais, nas ações de controle das migrações, realocação dos que pediram asilo, e reinstalação de pessoas necessitadas. Como uma operação de guerra, foi montada uma estrutura logística militar para acolher os venezuelanos, em território brasileiro. This article aims to analyze the international migration flux in the context of the Venezuelan refugee crisis in the northwestern arch of Brazil in the state of Roraima. Beyond the Venezuelan entry, this work also analyses the Brazilian capacity to admit the asylum requests that the country received between the years of 2018 and 2019, as well as the policies and actions in this matter. In this scenario, the Brazilian state adopted some measures that demanded solidarity, union, and the inter-state and non-estate work in the actions that deals with migration control, reallocation of those who required for asylum, and the resettlement of people in need. As a war operation, a military logistic was set up to welcome the Venezuelan in Brazilian´s territory.
The Presence of Other TB Cases in the Family as a Substantial Factor Influencing the Level of Knowledge and Perception of TB patients
Authors: Levani Yelvi , Alfaray Ricky Indra , Zharfan Rahmat Sayyid , Dewayani Astri , Fauzia Kartika Afrida , Saruuljavkhlan Batsaikhan , Paramita Ayu Lidya , Rahmayanti Maya , Mochtar Nur Mujaddidah , Musthofa Kamal , Nasrullah Dede , Subkhan Mohammad
Published: July 2021

Introduction: Indonesia is still among the top three contributors to the number of Tuberculosis (TB) patients in the world in 2017. The awareness about TB can be affected by the presence of other TB patients in the family. Perception and good knowledge in TB patients can increase obedient in treatment. This study aims to relate to the presence of other TB patients in the family environment with knowledge of TB patients.Methods: This study used cross-sectional design. Research respondents have taken using the consecutive sampling technique. Respondents were TB patients on category one anti-tuberculosis treatment at Siti Khadijah Sepanjang Hospital and several primary health centers in Sidoarjo region during February-March 2019. This study used a questionnaire which included sociodemographic, level of knowledge, and perception about TB.Results: The number of respondents in this study was 50 people aged 22-67 years old. The level of knowledge of the respondents was mostly good (82%) as well as perceptions regarding TB (78%). Of the 50 patients, 17 patients (34%) claimed some families also suffered from TB. The comparison between group with other TB patient and group without other TB patients in the family showed significantly different result in the level of knowledge (p=0,000) and perception (p=0,000). The presence of other TB cases in family increased level of knowledge and perception regarding TB significantly.Conclusion: The presence of other TB patients in the family environment can increase awareness so that it can increase the interest of TB patients to find information about TB.
Antihelmintic Treatment And Strategy To Eliminate Soil-Transmitted Helminth In Children
Authors: Thirafi Sacharissa Zerlina Tsarwah , El-Hakim Zaky Firmawan , Nugroho Lutfi Dewanda , Khangai Ayush , Puspitasari Dwiyanti
Published: July 2021

Introduction: Soil-transmitted helminthiasis (STH) is one of the neglected tropical diseases. These worm infections contributed to global child health. Children suffer from chronic disease and fail to reach their full physical and intellectual capacity. Antihelmintic treatment or deworming is recommended for controlling STH. World Health Organization is focusing predominantly on deworming school-age children. Even antihelmintic treatment has to be repeated regularly, children can reinfect if their environment contaminated. It needs a strategy to control STH and treating adults as well as a child.Methods: We searched the literature for relevant clinical research and articles using Google Scholar and PubMed which were published between 2014 and 2018 with keywords “soil-transmitted helminths”, “soil-transmitted helminthiasis”, combined with “eradication” and “elimination”. We excluded research and article which were not written in English. Our study included a total number of ten publications.Results: The studies mentioned that antihelmintic requires the control of STH transmission and need for the treatment in different age groups.Conclusion: According to our findings, the mass drug administration is recommended as a control strategy in both low and middle-income countries to reduce helminthiasis and schistosomiasis. High STH reinfection rate requires an integrated approach including the use of safe pure water, improvement for personal hygiene and sanitation, proper toilets, and reducing the practice of defecation in nature. The previous studies showed that studies focused on deworming using antihelmintic
Antimalarial Activity of Ethanol Extract of Noni Leaves (Morinda citrifolia) towards Parasitemia, Splenomegaly, and Hepatomegaly in Plasmodium berghei ANKA Infected Mice
Authors: Rahayu Putri , Hernaningsih Yetti , Arwati Heny
Published: July 2021

Introduction: Malaria is one of the infectious diseases found in tropical countries and sub-tropical countries. In 2016 there were an estimated 445,000 people died to malaria. Alternative medicine is needed, such as natural based ingredient. Morinda citrifolia or noni plant is a medicinal plant found in all parts of Indonesia which has many benefits, such as antibacterial, analgesic, anticancer, antioxidant, and anti-inflammatory. The aims of this study were to determine the antimalarial activity of ethanol extract of noni leaves and its effect on splenomegaly and hepatomegaly.Methods: Extract of noni leaves was prepared by maceration using ethanol solvent. In vivo experiments were conducted using Plasmodium berghei infected BALB/c mice treated with the doses of 100, 10, 1 mg/kg body weight(BW) orally of ethanolic extract of noni leaves. Then, the percentage of parasitemia was calculated from day 1 to day 4 after treatment and at the end of the test, mice were sacrificed then spleen and liver were collected. Results: The highest parasite growth was found in the group treated with noni leaves ethanol extract at a dose of 1 mg/kg WB and vice versa. Probit analysis resulted in ED50 was 0.882 mg/kg WB. Spearmen test showed there was no correlation between doses and the size of splenomegaly with p=0,2 and between doses and the size of hepatomegaly with p=0,6.Conclusion: Ethanol extract of noni leaves possessed antimalaria activity and there was no correlation between doses of extract and t he splenomegaly and hepatomegaly.
High-Fat Diet Increases Serum HDL, but Not for LDL and HDL/LDL Ratio in MICE
Authors: Laksana Iqbal , Rejeki Purwo Sri , Herawati Lilik , Al Arif Mohammad Anam , Wardhani Indrayuni Lukitra
Published: July 2021

The use of a ketogenic diet with an increased proportion of fat is rampant lately, both as a therapy or even lifestyle. The use of a ketogenic diet is feared to cause dyslipidemia. It will also lead to atherosclerosis and thrombosis. This study aimed to determine the effect of a high-fat diet on HDL, LDL, and HDL/LDL ratio in mice. Thirty male Mus Musculus, 2-3 mo, 15-25 g divided into five groups diet. K1 (12% fat, 20% protein, 62% carb), K2 (30% fat, 60%protein), K3 (45% fat, 45% protein), K4 (60% fat, 30% protein) and K5 (75% fat, 15% protein) for 4 weeks. Feed and water by adlibitum. Blood for serum was taken from the ventricle, while in the measurement of HDL serum level, the LDL used ELISA. Normality of data analyzed by Shapiro Wilk, and homogeneity by Levene test. HDL serum was analyzed using equality test followed by Games Howell, LDL serum and ratio of HDL/LDL was tested by ANOVA followed by LSD with significance 0,05. HDL serum in K1 (62,50±9.94) mg/dL, K2 (78,40±18,76) mg/dL, K3 (79,00±3,81) mg/dL, K4 (80,00±2,16) mg/dL, and K5 (83,50±5,62) mg/dL with p<0,05 in K1, K2 to K3, K4 and K5. LDL serum in K1 (21,67± 4,80) mg/dL, K2 (23,00±12,70) mg/dL, K3 (18,40±4,34) mg/dL, K4 (24,00 ±1,83) mg/dL and K5 (22,00 ± 4,08) mg/dL with p>0,05. Ratio HDL/LDL K1 (3,01±0,91), K2 (4,10±1,86), K3 (4,53±1,5), K4 (3,35±0,34), and K5 (3,96 ± 1,25) with p>0,05.
Four Weeks Exercise in Vary Intensities Reduce More Inguinal Fat Than Perigonadal Fat in Mice
Authors: Lutfi Ahmad Rukhani , Liben Paulus , Herawati Lilik
Published: July 2021

Staphylococcus aureus (S. aureus) is the most common pathogen in humans that causes various infections. A variety of infections due to S. aureus are related to virulence factors, one of which is Toxic Shock Syndrome Toxin-1 (TSST-1) as the main cause of Toxic Shock Syndrome (TSS). This study aimed to explore the genetic pattern of the tsst-1 genes among MSSA and MRSA from clinical isolates of patients at Dr. Soetomo General Academic Hospital, Surabaya-Indonesia. This study performed a PCR test on 106 clinical samples of S. aureus isolated to determine the presence of the tsst-1 genes; subsequently, this study also performed phylogenetic analysis. The positive tsst-1 genes were found in 3 (5.7%) MSSA isolates and 2 (3.8%) MRSA isolates from 106 samples that were divided into 53 MSSA isolated and 53 MRSA isolates. There was no significant difference between the tsst-1 genes on both the MSSA and MRSA bacteria (p = 0.648). The positive tsst-1 genes were found in 1 (4.5%) of pus specimens and 2 (16.7%) of blood specimens from MSSA isolates. However, the positive tsst-1 genes were found in neither sputum nor urine specimens. The genes were found in 2 (16.7%) of blood specimens from MRSA isolates. Based on the phylogenetic tree, Indonesian tsst-1 isolated belonged to the same clade as Japan, Iran, Iraq, India, Egypt, and the United Kingdom. The prevalence of tsst-1 genes of both MSSA and MRSA from clinical isolates in Dr. Soetomo General Academic Hospital Surabaya was 5.7% and 3.8%, respectively. The tsst-1 genes of Surabaya-Indonesia, Japan, Iran, Iraq, India, Egypt, and the United Kingdom belonged to the same clade.
Risk Factors of Body Mass Index (BMI), Age of Menarche, Parity and Hormonal Contraception of Genu Osteoarthritis in Female Patients
Authors: Alisiya Alisiya , Sulistiawati Sulistiawati , Kurniawati Patricia Maria , Wardhani RR Indrayuni Lukitra
Published: July 2021

Osteoarthritis (OA) is a degenerative disease related to joint cartilage and commonly occurs in the knee joint. The 2013 National Survey recorded the prevalence of joint diseases in East Java was 26.9%. OA affected more women than men due to the estrogen and caused disabilities in many women. This study aimed to find the relationship between Body Mass Index (BMI), age of menarche, parity, and the use of hormonal contraceptives against OA in genu at Universitas Airlangga Hospital, Surabaya. This was an analytic observational study with a case-control approach. Data collection was carried out through a short interview using a questionnaire. The sample size was calculated using a formula and found that the study required 42 patients with OA in the case group and 42 patients without OA in the control group. The case group was dominated by patients with 56-60 years old age (62.1%), BMI 23-24.9 kg/m2 (58.7%), menarche age 12-13 years (53.6%), multiparous (52.6%), having contraception pill usage history (62.3%) particularly using combination pills (60.5%) with a mean duration of use > 1 year (56.8%). There was a relationship between BMI and type of hormonal contraceptive used against genu OA in female patients at Universitas Airlangga Hospital Surabaya.
Lower Level of Interleukin-6 and Hepcidin Found in Lower Density of Physical Exercise among Athlete During Pandemic of Covid-19
Authors: Purwani Deni , Sulistiawati Sulistiawati , Purwanto Bambang
Published: July 2021

The pandemic of Covid-19 affected entire daily human life worldwide, including sports activities among athletes. An athlete was pushed to suit their routine activities with a new health protocol for Covid-19 prevention. Some of them were programmed to train at home with a moderate density of exercise, but others were still in a high density of exercise. This study compared the serum level of hemoglobin (Hb), interleukin-6 (IL-6), and hepcidin among athletes with a high versus moderate exercise density training program during the pandemic. Thirty-four indoor soccer athletes of a soccer football school in Malang voluntarily registered as a subject. Half of them received moderate exercise density exercise programs, and others received high-density exercise programs during June-July 2020. Interleukin-6 and hepcidin level mean was found significantly lower in the moderate group compared to the high-density group. Hemoglobin level mean was found not different between those groups. The lower density of exercise influenced on IL-6 and hepcidin serum level of athlete, but not on hemoglobin level.
AN ANALYSIS OF TYPE I DILEMMA ZONE AT SIGNALISED INTERSECTIONS
Authors: AKGÜNGÖR Ali Payıdar , MERCAN Elif Zahide
Published: July 2021

Intersections, for vehicles coming from different directions, are conflict points in road networks. When a driver approaching a signalised intersection encounters the yellow light, he/she is in a dilemma either to safely stop or to pass through the intersection during clearance time. The decision to stop or to pass may change depending on some factors such as duration of yellow light, deceleration and acceleration rate, width of intersection, speed and length of vehicle, etc. This study aims to put forth the effects of some related factors affecting the length of the Type I dilemma zone. To perform this study, five factors including vehicle speed, maximum deceleration rate, perception-reaction time, clearance time, the total intersection width-vehicle length were considered and a total of 648 different traffic cases were investigated. The study results showed that the Type I dilemma zone length increased with the increase of speed, total intersection width-vehicle length and perception-reaction time, but decreased with the increase of clearance time and deceleration rate.
SHORTCOMINGS OF ACCOUNTING RECORDS OF BUSINESS RESULTS IN THE HOTEL INDUSTRY
Authors: Janković Sandra
Published: July 2021

Unatoč razvijenim modernim sustavima mjerenja poslovnog rezultata, hotelska industrija u Hrvatskoj još uvijek ostaje orijentirana tradicionalnim oblicima i vrlo sporo se prilagođava suvremenim sustavima. Od 1926. godine hotelska industrija posjeduje vlastiti sustav evidentiranja i izvješćivanja poslovnog rezultata. Istraživanja pokazuju da je u posljednjih desetak godina povećan broj hotelskih poduzeća u Hrvatskoj koji uvodi metodu USALI. Iako se u osam desetljeća svojeg postojanja USALI poboljšavao i prilagođavao, danas ne udovoljava zahtjevima modernih sustava mjerenja i upravljanja poslovnim rezultatom. Stoga ga treba nadopuniti modernim računovodstvenim metodama, koje će nadomjestiti njegove nedostatke. Predlaže se integracija s obračunom troškova procesa.
QUALITY MANAGEMENT IN TOURISM AND HOSPITALITY INDUSTRY
Authors: Vrtodušić Hrgović Ana-Marija
Published: July 2021

Snažna je konkurencija na tržištu uvjetovala razvoj novog pristupa upravljanju poznatog kao Upravljanje potpunom kvalitetom (TQM - Total Quality Management). Zbog važnosti koju kvaliteta ima u postizanju konkurentske prednosti i u hotelskoj su se industriji počeli primjenjivati sustavi upravljanja potpunom kvalitetom. Prilikom uvođenja ovih sustava hotelska poduzeća mogu koristiti različite pristupe koje će prilagoditi svojim uvjetima poslovanja. Pri tome se mogu koristiti tzv. "TQM standardi ili okviri" tj. nacionalni ili međunarodni standardi i nagrade za kvalitetu, a zbog svoje su široke primjene u radu dati okviri koje nudi međunarodni standard ISO 9001:2000 te modeli poslovne izvrsnosti Malcolm Baldrige National Quality Award i European Quality Award.
An evaluation of websites quality factors in agro travel and ecotourism
Authors: Lathiras Petros , Zopidou Anastasia , Mylonakis John , Tahinakis Panayiotis , Protogeros Nikolaos , Valachis Ioannis
Published: July 2021

Tourism is an information intensive industry and as a service industry, information is the most significant quality factor for the industry. E-tourism is part of electronic trade that includes the fastest developing technologies that assist to the hospitality and tourism strategic planning and management. The aim of this paper is to analyze and compare the quality of 3 Internet sites and detecting their strong and weak points by analyzing quality into its constituent dimensions. Research was carried out by personal interviews and via electronic mails to a sample of 413 persons and internet users, out of which 157 responded. Statistical analysis included simple and multiple comparisons ANOVA and t-tests. Research detected some medium quality ratings, as well as, some more positive evaluations of certain individual factors. The Internet sites that collected the highest ratings are Agrotravel (5.32), Guest inn (5.08) and Ecotourism (4.26). Elements considered important in all three web portals are the lack of interaction facilities and conversation sections and personalized options with user personal accounts. Emphasis must be paid on the design, information, interaction and overall quality of a web site.
Does restaurant performance meet customers' expectations? An assessment of restaurant service quality using a modified DINESERV approach
Authors: Marković Suzana , Raspor Sanja , Šegarić Klaudio
Published: July 2021

The purpose of this study is to determine restaurant service quality. The aims are to: (a) assess customers’ expectations and perceptions, (b) establish the significance of difference between perceived and expected service quality, (c) identify the number of dimensions for expectations and perceptions scales of modified DINESERV model, (d) test the reliability of the applied DINESERV model. The empirical research was conducted using primary data. The questionnaire is based on Stevens et al. (1995) and Andaleeb and Conway’s (2006) research. In order to meet survey goals, descriptive, bivariate and multivariate (exploratory factor analysis and reliability analysis) statistical analyses were conducted. The empirical results show that expectations scores are higher than perceptions scores, which indicate low level of service quality. Furthermore, this study identified seven factors that best explain customers’ expectations and two factors that best explain customers’ perceptions regarding restaurant service. The results of this study would help management identify the strengths and weaknesses of service quality and implement an effective strategy to meet the customers’ expectations.
Commercial Forest Carbon Protocol Over-credit Bias Delimited by Zero-threshold Carbon Accounting
Authors: Marino Bruno D.V. , Bautista Nahuel
Published: July 2021

Despite the use of commercial forest carbon protocols (CFCPs) for more than two decades, claiming ~566 MMtCO2e and a market value of ~USD $15.7 billion, comparative analysis of CFCP methodology and offset results is limited. In this study, five widely used biometric-based CFCPs are characterized, and common characteristics and differences are identified. CFCP claims of net forest carbon sequestration are compared with results of directly measured CO2 by eddy covariance, a meteorological method integrating gross vertical fluxes of forest and soil carbon, and the only alternative non-biometric source of net forest carbon sequestration data available. We show here that CFCPs share a structural feature delimiting forest carbon values by zero-threshold carbon accounting (gC m-2 ≤ 0), a pattern opposite to natural emissions of forest CO2 exchange based on direct measurement and a fundamental biological constraint on net forest carbon storage (i.e., soil efflux, ecosystem respiration). Exclusion of forest CO2 sources to the atmosphere precludes net carbon accounting, resulting in unavoidable over-crediting of CFCP project offsets. CFCP carbon results are significantly different from global forest CO2 net ecosystem exchange population results (FluxNet2015 gC m-2) at the 95% to 99.99% confidence levels, inferring an annual median error of ~247% (gC m-2), consistent with over-crediting. Direct CO2 measurement provides an urgently needed alternative method for commercial forest carbon products that has the potential to harmonize global markets and catalyze the role of forests in managing climate change through nature-based solutions.
Fear of Missing Out and Problematic Social Media Use Among University Students in Turkey: Correlates and Further Analysis
Authors: Kırık Ali Murat , Çetinkaya Ahmet , Gündüz Uğur
Published: July 2021

This study examines the relationship of fear of missing out (FOMO) with heavy social networking among Turkish university students (aged 17 - 55). The perception of the possible role of parental supervision on online activities is also investigated. Factor analysis of FOMO scale led us to evaluate the construct under two dimensions as (1) fear of missing experience and (2) fear of missing activity. The results revealed that fear of missing activity increases social media intrusion while fear of missing experience is found to have no significant effect. The reverse relationship is also valid: an urge to use social media predicts fear of missing out (activity and experience). Fear of missing experience is associated with problematic social media use (PSMU) and a high desire to use social media. The results additionally demonstrate that students aged 30 and older believe more in the requirement of parental control than those aged 17-22.
A Paper-based Immunofluorescent Device for the Detection of SARS-CoV-2 Humanized Antibody
Authors: Kasetsirikul Surasak , Umer Muhammad , Soda Narshone , Sreejith Kamalalayam Rajan , Shiddiky Muhammad J. A. , Nguyen Nam-Trung
Published: July 2021

We report on an immunofluorescent paper-based assay for the detection of severe acute respiratory symptom coronavirus 2 (SARS-CoV-2) humanized antibody. The paper-based device was fabricated by using lamination technique for easy and optimized handling. Our approach utilises a two-step strategy that involves (i) initial coating of the paper-electrode with recombinant SARS-CoV-2 nucleocapsid antigen to capture the target SARS-CoV-2 specific antibodies, and (ii) subsequent detection of SARS-CoV-2 antibodies using fluorophore-conjugated IgG antibody. The fluorescence readout was observed with fluorescence microscopy. The images were processed and quantified using a MATLAB program. The assay can selectively detect SARS-CoV-2 humanized antibodies spiked in PBS and healthy human serum samples with the relative standard deviation of approximately 6.4% (for n = 3). It has broad dynamic ranges (1 ng to 50 ng/µL in PBS and 5 to 100 ng/µL in human serum samples) for SARS-CoV-2 humanized antibodies with the detection limits of 2 ng/µL (0.025 IU/mL) and 10 ng/µL (0.125 IU/mL) in PBS and human serum samples, respectively. We believe that our assay has the potential to be used as a simple, rapid, and inexpensive paper-based diagnostic device with a portable fluorescent reader to provide point-of-care diagnosis. This assay can be used for rapid examination of a large batch of samples toward clinical screening of SARS-CoV-2 specific antibodies as a confirmed infected active case or to evaluate the immune response to a SARS-CoV-2 vaccine.
Epigenetics in Clinical Gynecology
Authors:   Peoples' Friendship University of Russia, Moscow, Russian Federation, Dubinskaya E.D. , Gasparov A.S. ,   Peoples' Friendship University of Russia, Moscow, Russian Federation, Kolesnikova S.N. ,   Moscow Medical University “Reaviz”, Moscow, Russian Federation, Kholban I.V. ,   Peoples' Friendship University of Russia, Moscow, Russian Federation, Babicheva I.A. ,   Peoples' Friendship University of Russia, Moscow, Russian Federation
Published: July 2021

The analysis of literature data has shown that various epigenetic mechanisms, both transgenerational and generational (associated with the peculiarities of present existence) have a significant influence on the formation of gynecological diseases. The analysis of the pathogenesis of gynecological diseases in terms of epigenetic mechanisms expands the possibilities of personalized prevention, prognosis and treatment. Key words: epigenetics, environmental factors, diabetes, endometriosis, polycystic ovary syndrome
Polymorphism of the ADRB2 gene as a predictor of preterm birth
Authors:   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation, Proklova G.F. , Sokova E.A. ,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation,   Scientific Centre for Expert Evaluation of Medicinal Products, Moscow, Russian Federation, Kazakov R.E. ,   Scientific Centre for Expert Evaluation of Medicinal Products, Moscow, Russian Federation, Chilova R.A. ,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation, Zhukova E.V. ,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation, Akopov K.O. ,   S.S.Yudin City Clinical Hospital of the Department of Healthcare of the City of Moscow, Moscow, Russian Federation
Published: July 2021

Tocolytic therapy with the use of β2-agonist hexoprenaline is used to prolong pregnancy. Polymorphisms of the ADRB2 gene can affect the efficacy and safety of this drug, including missense mutations associated with the Gly16Arg and Gln27Glu substitutions. Objective. To study the role of the ADRB2 gene polymorphism in preterm birth, as well as the efficiency and safety of tocolytic therapy with hexoprenaline. Patients and methods. 120 pregnant women were examined. The main group included 60 pregnant women who were at risk of preterm birth and to whom intravenous tocolytic therapy with hexoprenaline was performed. In the control group (n = 60), there was a woman whose pregnancy was not accompanied by the threat of preterm birth, and delivery itself was emergency and spontaneous. The identification of the Gly16Arg and Gln27Glu polymorphisms of the ADRB2 gene was carried out by the PCR-RFLP method. Results. In pregnant women with the threat of premature labor, the 16Arg allele (p = 0.028) was less common, and the 16Gly/Gly genotype (p = 0.027) of the ADRB2 gene was reliably more common. Adverse reactions to hexoprenaline occured in 53% of pregnant women: in 47%, it was tachycardia, in 6% – headache. Their incidence was not associated with the ADRB2 gene polymorphism. Conclusion. The effectiveness of hexoprenaline is lower in the carriers of genotypes indicating high or low expression of β2-adrenoreceptors. Key words: hexoprenaline, genotyping, single-nucleotide polymorphisms, preterm birth, tocolytic therapy, ADRB2
Gobernanza y Política Laboral en México: Opciones ante la precariedad
Authors: Medina Parra Rosa Isabel , Ramos González José María
Published: July 2021

Las principales aproximaciones a la gobernanza plantean que ésta gira en torno a la eficiente gestión de las políticas públicas. Así, el presente trabajo de investigación se orienta a analizar la incidencia de la gobernanza en la eficacia del Programa Sectorial de Trabajo y Previsión Social 2020-2024, específicamente bajo el contexto de los efectos de la pandemia del Covid-19; de entre los cuales destacan la desigualdad social y precariedad laboral, cuya agudización afectará el nivel de vida de los grupos en situación de vulnerabilidad en México. Por lo que es fundamental impulsar un modelo de gobernanza que promueva el PSTPS generando alternativas de empleo.
Obtención de certificación ISO 9001-2015 bajo condiciones de contingencia de pandemia COVID 19. El caso de una MyPE de manufactura en Ciudad Juárez
Authors: Tarango Hernández Luz Elena , Sandoval Chávez Diego Adiel , Terrazas Mata Luz Elena
Published: July 2021

En plena pandemia COVID 19, una microempresa manufacturera en Ciudad Juárez llevaba varios meses diseñando, mejorando e implementando un Sistema de Gestión de Calidad (SGC) para acceder a una certificación. Sin embargo, se suspendieron las actividades productivas por la contingencia sanitaria, reduciéndose al mínimo los requerimientos de los clientes, lo que hizo necesario convenir con los empleados para recibir 60% de su salario y evitar despidos. Al tiempo que se presenta la autorización para reanudar operaciones, no se tenían órdenes de trabajo. Súbitamente, un importante cliente establece el requerimiento de la certificación en ISO 9001-2015 para otorgar nuevas requisiciones. De esta manera, sin órdenes, financiamiento o recursos para mantener operaciones, se enfrenta el dilema de continuar con los planes de certificación o disponer de los escasos ingresos para solventar los salarios. Este trabajo describe y discute las experiencias y lecciones en el logro de la certificación en tan adversas circunstancias.
Relación entre el clima escolar y el rendimiento académico en estudiantes de ingeniería industrial
Authors: Robles Camargo Juan Carlos
Published: July 2021

El presente estudio se realiza para aproximar la relación entre clima escolar y rendimiento académico, abordándola desde la perspectiva de estudiantes de ingeniería industrial de una universidad privada de Bogotá. Se realizó investigación de carácter mixto-secuencial, con alcance que inició de tipo descriptivo definiendo las variables de estudio para posteriormente asociarlas y girar a tipo correlacional, definiendo la hipótesis en que la percepción del clima escolar favorable está directamente relacionada con el rendimiento académico. Se realizó un recorrido bibliográfico para establecer el estado del arte en materia administrativo-académica, generando un acercamiento a las teorías administrativas y su aplicación en el ámbito académico, definiendo tres dimensiones (Institucional, Aula e Intrapersonal), agrupando 13 categorías como eje de este estudio. Se construyó el instrumento de medición arrojando una confiabilidad del 0.96 para el coeficiente Alpha Cronbrach y una validez del 0.92 para el índice KMO con un nivel de significancia de 000.
PENGARUH KELEMBABAN TANAH TERHADAP TAHANAN PENTANAHAN STUDI KASUS PADA GARDU INDUK KEMAYORAN 150 KV
Authors: Rahmawati Fajri Latiefa  , Irzan Zakir  , Massus Subekti
Published: July 2021

Nilai tahanan pentaahan pada Gardu Induk harus mendekati 0 Ω atau kurang dari 1 Ω, dan dipengaruhi oleh tahanan jenis tanah dan metode sistem pentanahan yang digunakan. Tahanan jenis tanah dipengaruhi oleh faktor eksternal, salah satunya adanya kelembaban tanah. Tujuan dari penelitian ini adalah mengetahui pengaruh kelembaban tanah terhadap nilai tahanan pentanahan, dan mengetahui pengaruh yang akan terjadi jika tahanana pentanahan gardu induk melebihi nilai standar IEEE Std 80-2000 yaitu kurang dari 1 Ω. Penelitian ini melakukan pengukuran aktual tahanan pentanahan dengan sistem driven rood dan tahanan pentanahan dengan sistem grid saat kondisi tanah basah dan tanah kering, serta perhitungan tahanan pentanhan grid Gardu Induk Kemayoran 150 kV dalam kondisi tanah kering dan tanah basah dengan menggunakan perhitungan manual berdasarkan IEEE Std 80-2000, dan perhitungan menggunakan software ETAP 12.6. Dalam penelitian ini ditemukan bahwa kelembaban tanah dapat mempengaruhi nilai tahanan pentanahan, dengan berdasarkan saat kondisi tanah kering nilai tahanan pentanahan lebih tinggi dibandingkan saat kondisi tanah basah Hasil pengukuran tahanan pentanahan dengan sistem driven rood menunjukkan nilai tahanan pentanahan adalah 27,72 Ω saat kondisi tanah kering dan 18,92 Ω saat kondisi tanah basah, hasil pengukuran tahanan pentanahan dengan sistem grid menunjukkan nilai tahanan pentanahan adalah 0,076 Ω saat kondisi tanah kering dan 0,049 Ω saat kondisi tanah basah, hasil perhitungan manual tahanan grid adalah 0,078 Ω untuk kondisi tanah kering dan 0,056 Ω, dan hasil perhitungan ETAP tahanan grid adalah 0,071 Ω untuk kondisi tanah kering dan 0,051 Ω untuk kondisi tanah basah.
Komunikasi Dialogis Berbasis Budaya Lokal Sekaten (Studi terhadap Abdi Dalem Keraton Yogyakarta)
Authors: Rahmawati Alfiana Yuniar
Published: July 2021

ABSTRAK

Sebagai negara yang kaya akan keragaman budaya, suku, maupun agama, Indonesia memiliki tantangan dan masalah pluralitas sebagai dampak dari pengalaman religius masyarakat yang multiagama. Hal ini ditandai dengan banyaknya konflik dan kekerasan di berbagai daerah yang diakibatkan oleh minimnya komunikasi dialogis antarumat beragama. Hadirnya komunikasi dialogis sejatinya dapat menjadi penengah segala permasalahan dan konflik keagamaan. Komunikasi dialogis juga dapat menjadi perekat kerukunan sekaligus sebagai media untuk menumbuhkan pluralitas di tengah masyarakat multiagama. Artikel ini menemukan bahwa adanya tradisi lokal sekaten dapat menjadi media komunikasi dialogis untuk menciptakan persatuan dan kerukunan di tengah masyarakat abdi dalem keraton yang dikenal dengan masyarakat multiagama. Selain itu, hadirnya tradisi sekaten juga mampu mewujudkan masyarakat abdi dalem menjadi masyarakat yang inklusif pluralis terhadap segala perbedaan yang ada di lingkungan keraton baik perbedaan suku, agama, maupun tingkatan jabatan yang dimiliki oleh abdi dalem keraton Yogyakarta Hadiningrat.

 

Kata Kunci: Komunikasi dialogis, Sekaten, Abdi Dalem Keraton

 

 
Religious Syimbols and the Maintenance of Social harmony in Lombok, West Nusa Tenggara
Authors: Muhtar Fathurrahman
Published: July 2021

Symbols have been a crucial part of all religions in the world for they can represent religious values, ideas, and events. This study seeks to examine the meaning of religious symbols in Lombok, West Nusa Tenggara, and their role in maintaining socio-religious harmony in the region. Qualitative and interpretative in nature, data collection techniques in this study were carried out through interviews, observation, and documentation. Meanwhile, data analysis employed a grounded theory design. The results of this study indicate that the symbols of religious pluralism are visible on the Pura Meru (next to the Nurul Falah mosque), on the statues of various religious figures at the Pura Mayura, and on the Pura Lingsar, a home for an ancient building called Kemalik. These symbols have been recognized as common properties of Hindus and Muslims and as places to get blessings. There is also the Topat War festival which is a legacy of Muslim and Hindu traditions used as a medium to pour out any form of anger among religious adherents and then end with peace. Those symbols are believed to be able to foster togetherness and harmony in Lombok, West Nusa Tenggara. In general, these religious symbols have made Cakranegara and Lingsar peaceful areas free from religious conflicts to date.
NUANSA POLITIK DALAM MEMAHAMI HADIS: Analisa Metodologis-Historis
Authors: Syawqi Abdul Haq , Khatibul Umam Muhammad
Published: July 2021

Tulisan ini merupakan kajian terhadap adanya nuansa politis dalam memahami hadis. Kajian ini menjadi sangat penting karena karena ketika berbicara hadis, maka kita juga akan membincang mengenai orang-orang dan aliran politiknya dalam hadis tersebut yang berakibat pada kontroversi dalam memahami hadis. Metode penelitian ini menggunakan penelitian kualitatif, dimana data-data yang ada kemudian dipahami dan dianalisa dengan menggunakan metode kritik dan historis hadis pada pendekatannya. Sejalan dengan itu tulisan ini memetakan berbagai aliran dalam hadis sekaligus bagaimana pemahaman mereka terhadap suatu hadis. Hasil penelitian memperlihatkan bahwa terdapat setidaknya tiga atau lebih aliran politik dalam kesejarahan hadis yakni Sunni. Syiah, Muawiyah, Muktazilah dan lain lain.  Perbedaan kelompok ini telah menstrukturkan pemahaman terhadap hadis dalam metodologis-historisnya. Perbedaan pemaknaan kelompok ini akan juga sekaligus berkosekuensi pada pemaknaan terhadap hadis itu sendiri. Penelitian ini menyimpulkan bahwa berdasarkan metode dalam ilmu hadis dan sejarahnya, terdapat perbedaan dalam faksi politik dimana perbedaan ini akan berpengaruh pada pemahaman hadis.

[Political Nuances in Understanding Hadith: Methodological-Historical Analysis. This paper is a study of the political nuances in understanding hadith. This study is very important because when we talk about hadith, we will also talk about the people and their political flow in the hadith which results in controversy in understanding hadith. This research method uses qualitative research, where the existing data is then understood and analyzed using the critical and historical method of hadith as an approach. So this paper maps out the various schools of hadith as well as their understanding of a hadith. The results show that there are at least two political schools in the history of hadith, namely Sunni. Shia, Muawiyah. The differences in these groups have structured the understanding of hadith in its historical-methodological terms. The difference in the meaning of this group will also have consequences on the meaning of the hadith itself. This study concludes that based on the method in hadith science and its history, there are differences in political factions where these differences will affect the understanding of hadith.]
O controle externo da Administração Pública e a tripartição de poderes
Authors: Pinheiro Chagas Gabriel Costa , Cammarosano Marcio
Published: July 2021

Com o maior exercício do controle externo da Administração Pública por parte do Judiciário e até mesmo pelo Tribunal de Contas da União, a noção daquele instituto hoje ganha contornos não imaginados quando de sua concepção, à medida que hoje Judiciário e o Tribunal de Contas exercem, em boa medida, funções de coparticipes da Administração Pública, dividindo o papel de executores de políticas públicas e, muito frequentemente, assumindo um papel de instância recursal das decisões administrativas ainda que não eivadas de ilegalidade. Nessa amplificação do controle externo da Administração Pública, passa a ser inevitável uma análise a respeito de sua pertinência com a separação constitucional de poderes, tendo em vista que há uma ingerência cada vez mais profunda em competências e prerrogativas confiadas a outros poderes.
Atuação estatal por indução: tributação extrafiscal como instrumento de efetivação das políticas públicas
Authors: Motta Fabrício , Freitas Leonardo Buíssa , Freitas Gabriel Buíssa Ribeiro
Published: July 2021

O presente estudo pretende demonstrar a relevância da tributação extrafiscal como instrumento para a atuação estatal tanto na vida econômica quanto em questões sociais. Com a evolução do constitucionalismo, o Estado passa a exercer maior intervenção no domínio econômico, passando a governar por meio de políticas públicas. Nesse contexto, a função indutora da tributação se revela imprescindível para a consecução do desenvolvimento socioeconômico. A extrafiscalidade se apresenta então como instrumento necessário para a implementação de políticas públicas eleitas e assumidas pelo Estado.
Early Failure of the Paragon28 Phantom Hindfoot Fusion Nail
Authors: Friedmann Elizabeth M. , Sims Michael L. , Pattisapu Naveen , Bettin Clayton C.
Published: July 2021

Case:

Tibio-talar-calaneal fusion nails can be used to treat acute ankle fractures in patients with diabetes, Charcot arthropathy, or other comorbidities. Recently, Paragon28 released the Phantom Hindfoot Fusion Nail (Phantom nail) with a unique design feature—a proximal coil. We present a case of an ankle fracture-dislocation in a diabetic patient treated with the Paragon28 nail who experienced early implant failure.

Conclusion:

It is important for surgeons to understand that the proximal coil in the Phantom nail should not be considered part of the working length of the nail and may introduce a stress riser that may lead to early implant failure.
Addition of a Distal Femur Locking Plate to Augment Total Hip Arthroplasty in Osteogenesis Imperfecta
Authors: Charen Daniel A , Selverian Stephen , Adler Edward
Published: July 2021

Case:

We present a 55-year-old woman with osteogenesis imperfecta (OI) who underwent total hip arthroplasty (THA). She developed aseptic loosening of the femoral stem and was revised to a longer stem necessitating 2 osteotomies because of the proximal femur varus deformity. This was complicated by implant subsidence. She ultimately required another revision adding a distal femur locking plate to augment construct stability.

Conclusion:

The abnormal anatomy and suboptimal bone properties in patients with OI present unique challenges when performing THA. More aggressive prophylactic fixation to improve construct stability and prevent fracture may be necessary in this patient population.
Posterior Spinal Fusion for Scoliosis in the Oldest Reported Patient with Crane-Heise Syndrome
Authors: Engler Ian D. , Finch Daniel J. , Vasavada Kinjal D. , Braun Stuart V.
Published: July 2021

Case:

A 14-year-old adolescent girl with Crane-Heise syndrome—the oldest such patient in the literature—presented to our clinic with progressive scoliosis, including a 90° T6-L3 apex right curve. She underwent a T3-pelvis posterior spinal fusion. Intraoperatively, she had small, poorly visualized upper thoracic pedicles, incomplete fusion of the posterior spinal elements, and limitations of intraoperative neuromonitoring. Adherence to dysplastic scoliosis principles allowed for an uncomplicated procedure with an excellent correction.

Conclusion:

We discuss the surgical management of scoliosis in an adolescent with Crane-Heise syndrome. This is a very rare skeletal dysplasia, with 9 reported cases in the literature.