bluuebunny/crossref_metadata_2025 huggingface dataset:
Academic Staff Direct Participation in Managing Higher Education Institutions – Pilot Study Report
Authors: Szelągowska-Rudzka Katarzyna
Published: December 2019

The aim of the study is to present the results of pilot study on academic staff direct participation (ASDP) in managing higher education institutions (HEI) (content, scope, intensity, practicality of impact), in key areas of its activity and its advantages and risks. The research was carried out under questionnaire survey method among academic staff of selected HEIs, in autumn 2018. It was found that ASDP applies to all areas of activity of these HEIs (content), primarily educating students; is full (academics participate in all stages of the decision-making process), has mainly operational scope (related to basic tasks in the position at work), less often strategic; it is perceived participation because the real impact of the respondents in managing HEIs is limited (passive form of participation dominates). The identified main benefits from participation indicate that ASDP can be an effective tool for creating commitment of academic staff in managing HEIs in handling their key areas of activity. The results presented are not representative (pilot study), but interesting. Therefore, the author is planning to carry out in-depth research on ASDP in managing HEI in the future.
“POTENTIALLY SURVIVABLE” CASUALTIES — RESERVE TO REDUCE PRE-HOSPITAL LETHAILITY IN INJURIES AND TRAUMAS
Authors: Samokhvalov I. M. , Goncharov A. V. , Chirskij V. S. , Nosov A. M. , Golovko K. P. , Badmaev V. B. , Chupryaev V. A.
Published: December 2019

Battlefield lethality remains the most underexplored problem from the surgical point of view. 540 battle­field fatalities during the military operation in the North Caucasus region of Russia (1994–1996) were ana­lyzed. It was found that 25.4% of all “Killed In Action” refer to the group of potentially survivable. Common causes of combat death in this group were prolonged hemorrhage (78.1%), tension pneumothorax (19.0%), and hemopneumothorax (2.9%). Reducing mortality can be attained due to introduction of new means of control for life-threatening consequences of injuries, improving tactical evacuation, as well as training mili­tary personnel in providing combat lifesaver care.
EMERGENCY DEPARTMENT. ROLE IN WORK OF SURGICAL SERVICE
Authors: Linets Yu. P. , Artyukhov S. V. , Zaitseva T. E. , Chikin A. E.
Published: December 2019

The article is devoted to the analysis of the work of the surgical service of the urban multidisciplinary hospital before and after the opening of the emergency department. Based on the data obtained, the role of the emergency department in the work of the surgical profile has been identified, nosologies and prospective groups have been identified to increase the flow of patients in the emergency department.
TREATMENT OF ACUTE URINARY RETENTION CAUSED BY BENIGN PROSTATE HYPERPLASIA IN THE UROLOGY DEPARTMENT OF HOSPITAL
Authors: Kalinina S. N. , Burlaka O. O. , Alexandrov M. S. , Vydrin P. S.
Published: December 2019

In the article the results of conservative and operative treatment of 122 patients ranging in age from 42 to 80 years of age with acute delay of urine caused by benign prostate hyperplasia in the urology Department Alexander Hospital 2016 to 2018 years. n men, the most common cause of SSM is safe giperplazia (adenoma) prostate (BPH), found in the 45–53% of observations, tending to cause heart attacks in prostate tissue and in­creased Alpha-adrenergic activity. The main pathogenetic factor SSM in men is BPH, where heart attacks occur in the prostate tissue and increased Alpha-adrenergicheskaja activity. In 1 group comprised 42 patients diag­nosed for the first time, SSM, caused by BPH, in Group 2–80 patients with multiple SSM caused by BPH. All patients of Group 1 after combination therapy of Alpha alfuprost MICRORAION adrenoblokatorom in com­bination with jelefloksom noted restore self-sustaining urination. In Group 2 at 72 patients recovered partially and urinating they have plus sizes BPH, they performed Transurethral enucleation of BPH with positive effect.
ULTRASOUND DIAGNOSTICS IN THE WORK OF AN EMERGENCY MEDICAL CARE (PROTOCOLS OF THE URGENT ULTRASOUND RESEARCH. PART II)
Authors: Bulach T. P. , Afanas’eva I. V.
Published: December 2019

Diagnosis and primary care for unstable patients with hypotension and shock should be accurate and prompt. Ultrasound is ideal for assessing critically ill patients in a state of shock, it allows direct visualization of pathology and differentiation of shock conditions. Rapid Ultrasound in Shock (RUSH) meets the basic requirements of emergency medicine — speed, information content, safety, the ability to dynamically control. This bedside protocol demonstrates the speed and accuracy of determining the etiology of shock in the hands of an ambulance doctor. According to the RUSH protocol, three key physiological processes are evaluated, which are called: pump, reservoir and pipes, which allows a systematic approach to the study
EFFICIENCY OF PRE-HOSPITAL DIAGNOSIS OF THE STROKE
Authors: Gorbachev V. I. , Anuryev A. M. , Petrovа I. L. , Karetnikov I. A. , Gorbachevа S. M. , Kovalevа N. T. , Shnyakin P. G.
Published: December 2019

Purpose of the study. To assess the quality of diagnosis cerebrovascular accident (CA) at the pre-hospital stage in patients brought to the regional vascular center.  

Material and methods. 2708 case histories of the emergency department and accompanying sheets of first aid in patients with a guiding diagnosis of CA and 973 medical records of impatient in the regional vascular center were analyzed.  

Results and conclusion. Of the 2708 patients admitted with a diagnosis of CA, 973 people were hospitalized. Among hospitalized patients, the diagnosis of stroke was confirmed in 96.5% of cases. The most frequent diseases that were mistakenly diagnosed as a stroke turned out to be: diabetes, traumatic brain injury and brain neoplasms, etc. Confirmation of the guiding diagnosis during self-circulation was 36.6%, when delivered by ambulance crews — 39.8%, air ambulance — 86.7% and by sanitary transport — 16.5% of cases.
IMPACT OF COMBORBIDE LOAD ON CLINICAL COURSE OF INFERIOR WALL MYOCARDIAL INFARCTION WITH RIGHT VENTRICULAR INVOLVEMENT
Authors: Glavatskikh K. Yu. , Lukyanova I. Yu. , Shalnev V. I. , Pchelin I. Yu.
Published: December 2019

The article presents data on the frequency and structure of comorbid pathology in patients with inferior wall myocardial infarction with right ventricular involvement. Its relationship with the clinical course of myocardial infarction in the acute period was studied. It was shown that patients with inferior wall myocardial infarction with right ventricular involvement have a high comorbid load. It was revealed that a more severe course of the acute period of myocardial infarction in these patients was associated with chronic cerebrovascular ischemia, fatty liver, chronic heart failure I–IIa stages, type 2 diabetes mellitus and obesity.
PATHOMORPHOLOGICAL CHARACTERISTICS OF URGENT DISEASES OF THE FEMALE GENITAL SPHERE
Authors: Povzun S. A. , Novitskaja N. Yu. , Saiko A. S. , Il’ina V. A. , Ermolaeva M. M. , Boroday E. A.
Published: December 2019

The results of the analysis of the pathomorphological profile of the histologocaly verified pathology of the female genital sphere in the practice of the emergency hospital are presented. The role of pathohistological examinations in the diagnosis of the diseases and their structure in comparison with the such one in hospitals providing gynecological care routinely are discussed.
Anzóis, redes e pescadores
Authors: Silva Lucas Antonio da , Gaspar Maria Dulce
Published: December 2019

O objetivo do presente artigo é propor uma reflexão sobre a pesca no registro arqueológico, por meio das associações entre pescadores e materiais observados em uma comunidade pescadora da Barra do João Pedro, em meio ao rosário de lagoas, do litoral norte do Rio Grande do Sul. A partir das contribuições da socioantropologia da pesca, da Arqueologia dos sambaquis e da etnoarqueologia buscar-se-á os fundamentos para tal proposição. Observando que a materialidade se encontra no centro dessas argumentações, os anzóis, redes e pescadores serão o eixo para desvelar essa associação entre corpos e artepescas.
Materiais e fluxos na Amazônia Colonial
Authors: Muniz Tiago Silva Alves
Published: December 2019

O estudo da materialidade pode revelar aspectos sociais e econômicos relacionados à arqueologia da etnicidade quando situado em seu contexto histórico. Nesse sentido, escolhas tecnológicas, decorações plásticas aplicadas à cerâmica utilitária, vasilhames do tipo “monkey jars” e a interpretação das demais categorias materiais evidenciam um contexto relacionado ao fluxo de materiais na região de Santarém (Pará) durante os séculos XVIII e XIX. Tais fluxos demonstraram, além dos indígenas, a presença de africanos escravizados na Amazônia Colonial. O objetivo deste trabalho é abordar o contexto da Diáspora Africana com dados sobre zonas de captura, taxas de embarque e reembarque e elementos da cultura material capazes de revelar a agência dessas pessoas sujeitas à diferença colonial.
Alteridades técnicas no Brasil Pleistocênico
Authors: Ramos Marcos Paulo de Melo , Boëda Eric
Published: December 2019

A presente nota de pesquisa é um sobrevôo de parte do sistema de raciocínios aplicados na avaliação da antropicidade das coleções líticas estudadas no âmbito da atual Missão Franco-Brasileira do Piauí, realizada no Parque Nacional Serra da Capivara (PI). Neste texto, apresentamos, de maneira sucinta, a análise tafonômica, uma ferramenta de pesquisa derivada de avanços teóricos e metodológicos no lascamento experimental, utilizada no estudo de coleções com forte presença de seixos. Uma das premissas que guiam a reflexão na análise tafonômica pode ser resumida através da pressuposição: “a natureza não possui objetivos funcionais quando fratura uma rocha”. A pesquisa de doutoramento que embasa essa nota busca reconhecer as especificidades tecno-culturais das estruturas de lascamento pleistocênicas por meio da análise de coleções líticas evidenciadas em duas camadas sedimentares cronoestratigraficamente distintas no sítio arqueológico Vale da Pedra Furada.
Educação Patrimonial em Arqueologia
Authors: Andrade Cilcair
Published: December 2019

Partindo dos modelos de atuação dos pesquisadores no campo da Arqueologia Pública, identificados por Cornellius Holtorf e associados às premissas da Teoria de Educação e Trabalho Docente Conscientizador, cunhada por Paulo Freire, este artigo apresenta resultados do trabalho desenvolvido em sete projetos de Educação Patrimonial, entre 2009 e 2018, elaborados no âmbito do licenciamento ambiental. Foram consideradas informações relativas ao público envolvido, à contribuição das atividades para a construção do conhecimento, reconhecimento e apropriação do patrimônio, através da observação de quatro aspectos: categorias dos projetos, região geográfica onde o projeto foi realizado, transição entre público-alvo e público participante, e metodologia de realização.
Cachimbos brancos da região do Valongo
Authors: Hissa Sarah de Barros Viana , Lima Tania Andrade
Published: December 2019

Os cachimbos de caulim recuperados nas escavações do Cais do Valongo / Cais da Imperatriz e suas imediações foram atribuídos, na sua quase totalidade, ao século XIX. Foram utilizados e descartados no entorno e nas proximidades do cais, região portuária caracterizada por grande diversidade étnica. Tais pitos atestam a inserção do Rio de Janeiro, recém liberto das práticas monopolistas de Portugal, em uma economia cada vez mais global, na qual o trânsito de pessoas e mercadorias vindas de diferentes pontos era particularmente intenso. Nesse cenário, foi observada a predominância da fabricação francesa nos cachimbos de caulim encontrados, coerente com o que ocorreu na indústria e comercialização desses objetos no resto do mundo. Considerando as informações arqueológicas e alguns dados históricos sobre importação e venda de cachimbos no Rio de Janeiro, especula-se a respeito dos contextos em que eles podem ter sido utilizados, nessa cidade, nos oitocentos.
O protagonismo do Museu Nacional entre a pesquisa e a defesa pela preservação do patrimônio arqueológico de Itaipu (Niterói/RJ)
Authors: Andrade Marcela Nogueira de , Gaspar Maria Dulce
Published: December 2019

A partir da arqueologia de Itaipu, buscamos compreender as ações de preservação do patrimônio arqueológico e das pesquisas realizadas na área. A atuação teve como protagonistas as arqueólogas do Museu Nacional, Lina Kneip e Claudia Carvalho, mas também do arqueólogo Ondemar Dias do Instituto de Arqueologia Brasileira. Por meio de documentação disposta nos arquivos do Instituto do Patrimônio Histórico e Artístico Nacional, realizamos uma abordagem histórica sobre as pesquisas nos sítios arqueológicos Duna Grande, Duna Pequena e Camboinhas, e sobre a defesa da preservação do patrimônio arqueológico de Itaipu. Concluímos que para cada sítio foi realizada uma determinada ação e que a área ainda apresenta um potencial para ser pesquisada.
Olhando para o passado, pensando o futuro
Authors: Souza Marcos André Torres de , Buarque Angela
Published: December 2019

O artigo apresenta a retomada das pesquisas arqueológicas desenvolvidas pelo Museu Nacional na Ilha do Governador, Rio de Janeiro. Seu ponto de partida são as investigações lá realizadas de forma pioneira por arqueólogos nas décadas de 1960 e 1970. Utilizando uma abordagem dialógica, pretendemos apresentar algumas reflexões acerca das pesquisas na região, ontem e hoje. Buscamos, ainda, ao fim deste texto, encaminhar outras reflexões que têm se colocado como necessárias e de interesse para o trabalho de reconstrução após o incêndio que afetou o Museu Nacional em 2018.
Ensuring Civil and Political Rights in Vietnam Today - Some Theoretical, Legal, Practical Aspects
Authors: Nga Nguyen Thi Thanh
Published: December 2019

The article focuses on generalizing theoretical issues on civil and political rights, assurance of civil and political rights; ensuring civil and political rights in Vietnam through analyzing the provisions of the Constitution and laws and practices to ensure civil and political rights. On that basis, a solution is proposed to make a contribution to ensuring to make a contribution to ensuring civil and political rights in Vietnam in the near future.
Law Transformation in the Context Globalisation and International, Regional Integration
Authors: Thanh Ha Vu
Published: December 2019

Globalisation and regional integration has become typical in this contemporary context. These processes have changed the interaction between a national legal system and the international one towards the dominance of international law. At the same time, globalisation and regional integration have increasingly stimulated the proximity and interaction of national laws with other legal systems. This special context requires to establish approaches of transforming laws towards building an effective legal system for each country’s development and integration internationally and regionally.
Selecting a Suitable Remote Phosphor Configuration for Improving Color Quality of White Led
Authors: Lee Hsiao-Yi , Le Phan Xuan , Nguyen Doan Quoc Anh
Published: December 2019

When compared with two conformal phosphor and in-cup phosphor structures, the remote phosphor structure has higher luminescent performance. However, it is difficult to control the color quality of the remote phosphor structure, so it has become a research target in recent years. So far, there are two remote phosphor structures used to improve color quality including dual-layer phosphor configuration and triple-layer phosphor configuration. This study suggests using those two configurations to make multi-chip white LEDs (WLEDs) that can achieve adequate values in color rendering index (CRI), color quality scale (CQS), luminous efficacy (LE) and color uniformity. WLEDs with a color temperature of 5600 K are applied. Research results show that the triple-layer phosphor configuration is superior in CRI, CQS, LE. Besides, the color deviation decreases significantly, meaning that the color homogeneity increases with the triple-layer phosphor configuration. This can be demonstrated by analyzing the scattering characteristics of phosphor classes through Mie theory, thus making the research results more reliable and valuable for producing quality WLEDs. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.
Teaching Autonomy: Does Spanish Education System Achieve the Desired Effect?
Authors: Angel-Alvarado Rolando , Wilhelmi Miguel R. , Belletich Olga
Published: December 2019

Despite the Spanish curriculum for primary education establishes compulsory and elective subjects in order to promote teacher autonomy; curricular management is achieving the opposite of the desired effect according to teachers. This study aims statistically comparing the autonomy of educators who teach compulsory subjects and who only impart elective subjects. The method comprises a nonexperimental quantitative research design, establishing a random cluster sampling that has statistical representativeness from national standpoint. Results demonstrate that teachers who only impart elective subjects perceive a greater enjoyment toward pedagogical activity than the other group. In conclusion, it is reasonable to put the Spanish curriculum under scrutiny because its effectiveness for fostering the teacher autonomy is questioned.
Insensitivity of Magnetic Coupling to Ligand Substitution in a Series of Tetraoxolene Radical-Bridged Fe2 Complexes
Authors: Thorarinsdottir Agnes , Bjornsson Ragnar , Harris T. David
Published: December 2019

The elucidation of magnetostructural correlations between bridging ligand substitution and strength of magnetic coupling is essential to the development of high-temperature molecule-based magnetic materials. Toward this end, we report the series of tetraoxolene-bridged FeII2 complexes [(Me3TPyA)2Fe2(RL)]n+ (Me3TPyA = tris(6-methyl-2-pyridylmethyl)amine; n = 2: OMeLH2 = 3,6-dimethoxy-2,5-dihydroxo-1,4-benzoquinone, ClLH2 = 3,6-dichloro-2,5-dihydroxo-1,4-benzoquinone, Na2[NO2L] = sodium 3,6-dinitro-2,5-dihydroxo-1,4-benzoquinone; n = 0: SMe2L = 3,6-bis(dimethylsulfonium)-2,5-dihydroxo-1,4-benzoquinone diylide) and their one-electron-reduced analogues. Variable-temperature dc magnetic susceptibility data reveal the presence of weak ferromagnetic superexchange between FeII centers in the oxidized species, with exchange constants of J = +1.2(2) (R = OMe, Cl) and +0.3(1) (R = NO2, SMe2) cm−1. In contrast, X-ray diffraction, cyclic voltammetry, and Mössbauer spectroscopy establish a ligand-centered radical in the reduced complexes. Magnetic measurements for the radical-bridged species reveal the presence of strong antiferromagnetic metal–radical coupling, with J = −57(10), −60(5), −58(6), and −65(8) cm−1 for R = OMe, Cl, NO2, and SMe2, respectively. The minimal effects of substituents in the 3- and 6-positions of RLx−• on the magnetic coupling strength is understood through electronic structure calculations, which show negligible spin density on the substituents and associated C atoms of the ring. Finally, the radical-bridged complexes are single-molecule magnets, with relaxation barriers of Ueff = 50(1), 41(1), 38(1), and 33(1) cm−1 for R = OMe, Cl, NO2, and SMe2, respectively. Taken together, these results provide the first examination of how bridging ligand substitution influences magnetic coupling in semiquinoid-bridged compounds, and they establish design criteria for the synthesis of semiquinoid-based molecules and materials.
Selenolysine: A New Tool for Traceless Isopeptide Bond Formation
Authors: Dardashti Rebecca Notis , Kumar Shailesh , Sternisha Shawn M. , Reddy Post Sai , Miller Brian G. , Metanis Norman
Published: December 2019

Despite their biological importance, post-translationally modified proteins are notoriously difficult to produce in a homogeneous fashion using conventional expression systems. Chemical protein synthesis or semi-synthesis offers a solution to this problem; however, traditional strategies often rely on sulfur-based chemistry that is incompatible with the presence of multiple cysteine residues in the target protein. To overcome these limitations, we present the design and synthesis of γ-selenolysine, a selenol-containing form of the commonly modified proteinogenic amino acid, lysine. The utility of γ-selenolysine is demonstrated with the traceless ligation of the small ubiquitin-like modifier protein, SUMO-1, to a peptide segment of human glucokinase. The resulting polypeptide is poised for native chemical ligation and selective deselenization in the presence of unprotected cysteine residues. Selenolysine’s straightforward synthesis and incorporation into synthetic peptides marks it as a universal handle for conjugating any ubiquitin-like modifying protein to its target.
Highly Mesoporous Carbon Aerogel as Catalyst Support in Proton Exchange Membrane Fuel Cells
Authors: Gu Kevin , Kim Eric J. , Sharma Sunil K. , Rafailovich Miriam
Published: December 2019

Carbon aerogel possesses unique structural and electrical properties, such as high mesopore volume, specific surface area, and electrical conductivity, which make it suitable for use as a catalyst support in Proton Exchange Membrane Fuel Cells (PEMFC). In this study, we present a novel synthesis of highly mesoporous carbon aerogel via ambient-drying and investigate its application in PEMFCs. The structural effects of activation on carbon aerogel were also studied. The TEM, XRF, Non Localized Density Function Theory (NLDFT) and BJH analysis were carried out to observe the morphology and pore structure. Pt on carbon aerogel and activated carbon aerogel show efficient activity in both oxygen reduction and hydrogen oxidation reactions compared to Pt on Vulcan XC-72, with increases up to 715% and 195% in specific power density, respectively. The enhanced performance of carbon aerogel is attributed to its large specific surface area and high mesopore to micropore ratio. Accelerated stress tests show that carbon aerogel has comparable durability with Vulcan XC-72, while activated carbon aerogel is less durable than both materials. Thus, the mesoporous carbon aerogel provides an efficient, lower-cost alternative to existing microporous carbon material as a catalyst support in PEMFCs.
Software for the Analysis and Interpretation of Native Mass Spectrometry Data
Authors: Allison Timothy , Barran Perdita , Benesch Justin , Cianferani Sarah , Degiacomi Matteo , Gabelica Valerie , Grandori Rita , Marklund Erik , Menneteau Thomas , Migas Lukasz , Politis Argyris , Sharon Michal , Sobott Frank , Thalassinos Konstantinos
Published: December 2019

The last few years have seen a dramatic increase in applications of native mass and ion mobility spectrometry, especially for the study of proteins and protein complexes. This increase has been catalysed by the availability of commercial instrumentation capable of carrying out such analyses. Like in most fields, however, the software to process the data generated from new instrumentation lags behind. Recently, a number of research groups have started addressing this by developing software, but further improvements are still required in order to realise the full potential of the datasets generated. Here we describe practical aspects as well as challenges in processing native mass spectrometry (MS) and ion mobility-MS datasets, and provide a brief overview of currently available tools. We then set out our vision of future developments that would bring the community together and lead to the development of a common platform to expedite future computational developments, provide standardised processing approaches and serve as a location for the deposition of data for this emerging field.
Synthesis, Characterization and Study of DC Electrical Conductivity of Poly[MWCNT/Imidoselenium] Composite
Authors: Obeid Abeer O. , Al-Yusufy Fatma , Al-Aghbari Sama A , alshujaa omar , Gaber Yassin , Al-Washal Zinab A.
Published: December 2019

The chemical functionalization of amino multi-walled carbon nanotubes (MWCNT-NH2) by selenium dioxide (SeO2) was used to produce Poly [MWCNT/Imidoselenium] composite. The prepared poly-composite was characterized by FTIR, SEM, TEM, XRD, UV, DSC and TGA. The DC electrical conductivity of poly-composite was 4.3×10-4 S/cm due to the interaction between the nanotubes.
γ-Ray-Induced Proton Generation in Polymers: Quantifiable Single-Component Fluorescent Ratiometric Chemosensor
Authors: Pei Bin , Chen Biao , Su Hao , Huang Wenhuan , Miao Hui , Wang Yucai , Zhang Xuepeng , Zhang Guoqing
Published: December 2019

Detection of g-rays is of vital significance in various areas such as high-energy physics, nuclear medicine, national security and space exploration. However, most current spectrometry methods are typically based on ionization effects which are limited to electron counting techniques. Herein, we report an alternative, quantifiable g-ray chemosensor from a g-ray-induced proton generation process more sensitive to poly (methyl methacrylate) (PMMA) and polyvinyl chloride (PVC) by surveying a series of commercially available polymers. Accordingly, a pH-sensitive yet g-ray-stable fluorophore is designed, resulting in dramatic fluorescence shift from the blue (lem = 460~480 nm) to the red region (lem = 570~620 nm) after subjecting it to g-irradiation in PMMA or PVC films. A linear response of ratiometric fluorescence intensity (Ired/Iblue) to g-ray dosage in a wide range (80-4060 Gy) was established, which can be used as a visual dosimeter. Meanwhile, the discovery also opens new doors for proton-based radiation detection and chemistry.
Predicting NMR Relaxation of Proteins from Molecular Dynamics Simulations with Accurate Methyl Rotation Barriers
Authors: Hoffmann Falk , Mulder Frans , Schäfer Lars V.
Published: December 2019

The internal dynamics of proteins occurring on time scales from picoseconds to nanoseconds can be sensitively probed by nuclear magnetic resonance (NMR) spin relaxation experiments, as well as by molecular dynamics (MD) simulations. This complementarity oﬀers unique opportunities, provided that the two methods are compared at a suitable level. Recently, several groups have used MD simulations to compute the spectral density of backbone and side-chain molecular motions, and to predict NMR relaxation rates from these. Unfortunately, in the case of methyl groups in protein side-chains, inaccurate energy barriers to methyl rotation were responsible for a systematic discrepancy in the computed relaxation rates, as demonstrated for the AMBER ﬀ99SB*-ILDN force ﬁeld (and related parameter sets), impairing quantitative agreement between simulations and experiments. However, correspondence could be regained by emending the MD force ﬁeld with accurate coupled cluster quantum chemical calculations. Spurred by this positive result, we tested whether this approach could be generally applicable, in spite of the fact that diﬀerent MD force ﬁelds employ diﬀerent water models. Improved methyl group rotation barriers for the CHARMM36 and AMBER ﬀ15ipq protein force ﬁelds were derived, such that the NMR relaxation data obtained from the MD simulations now also display very good agreement with experiment. Results herein showcase the performance of present-day MD force ﬁelds, and manifest their reﬁned ability to accurately describe internal protein dynamics.
Mechanism of Anti-Cancer Therapy Alopecia: An Achievement
Authors: Vatsul Sharma
Published: December 2019

Editorial Comment by Dr. Vatsul Sharma, Editor-in-Chief, International Healthcare Research Journal (IHRJ)
Soft Tissue Cephalometric Norms for Bihar Ethnic Population
Authors: Rahul Munka  , Vaibhav Shandilya  , Harsh Kumar  , Abhishek Sinha
Published: December 2019

INTRODUCTION: A person's ability to recognize a beautiful face is innate, but translating this into defined treatment goals is problematic and various authors tried to relate the importance of soft-tissue esthetics with orthodontic diagnosis and treatment planning.

AIM AND OBJECTIVES: To derive the Soft Tissue Cephalometric norms for the normal, well-balanced and esthetically pleasing faces of the Bihar ethnic population and to compare them with pre-established norms.

MATERIALS AND METHOD: A sample of 60 subjects from an ethnic Bihar population residing in Patna, on the basis of facial symmetry, balance and pleasing appearance were observed from five sets of extra-oral photographs. Standardized lateral cephalometric radiographs were taken with metallic markers placed on various soft-tissue structures on the face using derma tapes. All lateral cephalometric films were traced and Soft Tissue Cephalometric Analysis was done.

RESULTS: Total facial length was significantly less in males as compared to the Caucasians with 117.50±1.74 as mean value. Males had significantly less protrusive upper and lower lips in projection to TVL with a mean value of 0.77±0.77 and -3.13±0.73 respectively. Lower lip length in females was significantly decreased with a decreased lower third facial height with a mean value of 62.27±1.46. Total facial length was significantly less in females with a mean value of 115.40±1.99. Females had significantly more protrusive upper and lower lips in projection to TVL with a mean value of 1.90±0.84 and 1.93±0.74 respectively.

CONCLUSION: The established norms in present study could be used as future reference for Orthodontic treatment in Bihar ethnic population.
İNTERNET VE AKILLI TELEFON BAĞIMLILIĞI İLE BENLİK SAYGISI VE YALNIZLIK ARASINDAKİ İLİŞKİNİN İNCELENMESİ
Authors: TOHUMCU Mehmet Utku , KARSLI Temel Alper , BAHADIR Erdi , KALENDER Bilal
Published: December 2019

İnternet
ve akıllı telefon bağımlılığı gelişen teknoloji ile birlikte psikoloji alan
dizininde sıklıkla incelenen konuların başında gelmiştir. Sürekli internet ve
akıllı telefon başındaki bireyler toplumdan uzaklaşmakta ve yalnızlaşmaktadır.
Bu durum bireylerin kendilerine olan saygılarında da azalmaya neden olmaktadır.
Bu çalışmanın amacı akıllı telefon ve internet bağımlılığı ile benlik saygısı
ve yalnızlık arasındaki ilişkinin incelenmesidir. Yapılan çalışmada ilişkisel
tarama modeli tercih edilmiştir. Bu amaçla yürütülen çalışmaya 137’si kadın ve
93’ü erkek olmak üzere 230 kişi katılmıştır. Katılımcılara içeriğinde;
demografik veri formu, akıllı telefon bağımlılığı ölçeği, Young İnternet
Bağımlılığı Testi Kısa Formu, Rosenberg Benlik Saygısı Ölçeği ve UCLA Yalnızlık
Ölçeği’nin bulunduğu anket formu uygulanmıştır. Yapılan korelasyon analizleri
sonucunda akıllı telefon bağımlılığı ile benlik saygısı ölçeği toplam puanlar
arasında negatif, orta düzeyde ve anlamlı; telefon bağımlılığı ile yalnızlık
ölçeği toplam puanları arasında pozitif ve düşük düzeyde anlamlı bir korelasyon
katsayısı elde edilmiştir. İnternet bağımlılığı ile benlik saygısı ölçeği
toplam puanlar arasında negatif, orta düzeyde ve anlamlı bir korelasyon
katsayısı; internet bağımlılığı ile yalnızlık ölçeği toplam puanlar arasında pozitif,
orta düzeyde anlamlı bir korelasyon katsayısı hesaplanmıştır. İnternetin kişi
için önemi, benlik saygısı ve yalıtılmışlık akıllı telefon bağımlılığını
yordamaktadır. İnternetin kişi için önemi, benlik saygısı, yaş ve yalıtılmışlık
internet bağımlılığını yordamaktadır.
Policy Rules in Macroeconomic Forecasting Models
Authors: Clark Todd E.
Published: December 2019

This Commentary describes how some of the Cleveland Fed’s macroeconomic forecasting models have been modified to use a Taylor rule for monetary policy. After briefly describing the Taylor rule implementation, the article shows that the Taylor rule included in one of our models successfully captures the course of monetary policy in the most recent episode of policy tightening.
When Might Federal Funds Rate Lift Off?
Authors: Knotek Edward S. , Zaman Saeed
Published: December 2019

The Federal Open Market Committee has been providing guidance to help markets anticipate when it will begin raising the federal funds rate target. The most recent guidance suggests that the target will not change at least until after an unemployment or inflation threshold is breached. We use a forecasting model to estimate when these thresholds are likely to be breached. We also consider how an inflation floor would affect the timing of liftoff.
Measuring Inflation Forecast Uncertainty
Authors: Knotek Edward S. , Zaman Saeed , Clark Todd E.
Published: December 2019

Looking across a range of statistical models, we consider the likely path of future inflation and the uncertainty surrounding the models' predictions. The models suggest that inflation is on a rising path, and while inflation forecast uncertainty is somewhat elevated relative to the norms of the last 20 years, core inflation uncertainty is relatively low. For both inflation rates, forecast uncertainty is much lower as of the first quarter of 2015 than it was around the Great Recession.
Current State and Development Trends of blockchain Technology in the Financial Sector
Authors: Krylov G. O. , Seleznev V. M.
Published: December 2019

The article analyzes the main reasons for the slow adoption of blockchain technology, in particular, in the financial sector. The authors critically analyzed the main declared properties of blockchain technologies: trust, security, decentralization, immutable data storage, lack of intermediaries, hardware protection against attacks, and openness. The aim of the study are to show that these blockchain properties are overestimated, the expectations of its adoption are inflated, and the delays in its adaptation outside of cryptocurrencies, in particular, in the financial sector, are natural. The article is based on a methodology for the qualitative and quantitative analysis of scientific publications and statistical sources on the blockchain adaptation from the perspective of the theory of diffusion of innovations, the conditions and the specifics of economic and sociological approaches for consensus-building. The study resulted in the following new systemic findings. Blockchain and distributed ledgers are not fundamentally new technologies. In general, they do not have the properties of the immutable data storage, trust, anonymity, low transaction and adoption costs. All current consensus technologies have fundamental faults. Cryptocurrency technology is original, but it was a private experimental solution to a specific ideological problem of the libertarian political agenda. Consensus does not provide trust. Delayed blockchain adoption, in particular in traditional financial institutions, is natural, since the technology does not show better results than current digital solutions, and traditional economic institutions have greater public trust. The practical implications of the findings are that they may be used by investors.
Comparative Analysis of ICO, DAOICO, IEO and STO. Case Study
Authors: Myalo A. S.
Published: December 2019

The article examines the problem of the ICO (Initial Coin Offering, from English — “initial offer of coins, initial placement of coins”). The information source is the ICO rating data of the return on investment in blockchain startups. The methodological base of the research is a situational comparative analysis of the ICO, DAOICO, IEO and STO and systematization of information. The author analyzes three new ICO models. The first one includes elements of Decentralized Autonomous Organizations (DAO). Its aim is to minimize the difficulties and risks associated with the ICO. The second model (Initial Exchange Offering (IEO), from English — “primary exchange offer”) is designed to minimize risks, liquidity problems and a delay in listing tokens at the end of the token sale. The third model — the Security Token Offering (STO, from English — “offer of security token”) — was designed to support real assets and comply with the SEC requirements. These models are a new direction for small and medium enterprises and investors. The absence of any scientific work emphasizes the relevance and scientific novelty of the study. The article is a follow-up of the empirical work related to the success of the ICO, as well as the basis for its revision using the case study results.
Financial Management of Innovative Activity
Authors: Shestak V. P. , Moreva E. I. , Tyutyunnik I. G.
Published: December 2019

Increasing investment activity is a key problem for Russia. Despite many state’s efforts, investment activity is low. The aim of the article is to propose an innovation management method based on a systems approach. The main objective of the research is to find an effective approach to optimizing state efforts to enhance financial management of innovative activity. The research methodology is based on the analysis of the enterprise closed innovation system. Economic and mathematical methods are used to represent the management function as an operator equation of the first kind. This allows to create a control algorithm to maximize the effectiveness. The methods of computational diagnostics and tomographic economics are used for the element-by-element analysis of the subsystems of the innovation system. The information base for the study was publications concerning the theory of management and business management. The possibility of applying computational diagnostic methods to optimize the financial management of innovation activity was proved by separating the controlling and controlled subsystems of the enterprise innovation system and observing all laws of production. A form of control functional was obtained on the sets of observable characteristics of the controlling and controlled subsystems while optimizing the results of innovative activity due to the feedback channel. The results of the study may be of practical interest for innovative projects in order to transfer the enterprise to innovative development, in particular, in relation to the restructuring of organizational structures and institutional support in the digital economy format.
Model Risk Analysis of Multiplier Technology Applied at Stock Valuation of Russian Companies
Authors: Minasyan V. B. , Ivko D. G.
Published: December 2019

This work is a new direction in the authors’ previous study on applying the market multipliers in assessing the value of oil and gas companies. The work is based on the findings of statistical studies of multipliers calculated for the industry, as well as their volatility over a 12-year period — from 2006 to 2017 inclusively, as exemplified by 46 companies from nine sectors of the economy of the Russian Federation. The analysis of the risk measures Value-at-Risk (hereinafter VaR) and Expected Shortfall (hereinafter ES) was conducted by means of volatility calculated in different ways. In particular, the multiplier volatility was introduced by V. B. Minasyan. It was established that for all nine sectors of the Russian economy, calculated with conventional stock volatility statistics (when possible), risk valuation measures VaR and ES led to lower calculated risk values compared to those calculated using multiplier volatility. The results of the study are of interest to evaluators, investors and other interested parties, as it allows to analyze the general behavior of the stock value in Russian companies and to compare the change in indicators of various economic sectors in terms of multiplier technology.
Üniversite Öğrencilerinin, Sihir, Büyü ve Tabiatüstü Güçlerle İlgili Tutumlarının İncelenmesi
Authors: KARTOPU Saffet , ÜNALAN Abdurrahman
Published: December 2019

İnsanoğlu var olduğu günden itibaren bilinmeyene karşı merak içerisinde olmuştur. Nitekim edebi ve kutsal metinler, arkeolojik kalıntılar, mağaraların duvarlarına yapılmış olan resimler, heykeller vb. incelendiğinde hemen her toplumda sihir büyü ve tabiatüstü güçlere başvurulduğu görülmektedir. Bu noktada günümüz modern toplumunda yaşayan bireylerin sihir, büyü ve tabiatüstü güçlerle alakalı tutumlarının belirlenmesi, bu inançların sürekliliğini anlamak açısından önem kazanmaktadır. Toplumun genç ve göreli olarak eğitimli bir kesimini oluşturan üniversite öğrencilerinin konuyla ilgili tutumlarını ortaya koymak, toplumun gelecekteki değerlerini ve eğilimlerini yordamak açısından elverişli olacaktır. Bu amaçla makale üniversite öğrencilerinin cinsiyet, eğitim alınan fakülte türü, akademik başarı, aile dindarlık ve öznel dindarlık değişkenleri açısından sihir, büyü ve tabiatüstü güçlerle ilgili tutumlarını belirlemeye odaklanmaktadır. Kahramanmaraş Sütçü İmam Üniversitesinde İlahiyat Fakültesi (N:100, %24,6), Edebiyat Fakültesi (N:100, %24.6), İktisadi ve İdari Bilimler Fakültesi (N: 103, %25,3), Güzel Sanatlar Fakültesi (N: 46, %11,3) ve diğer fakültelerin (N: 58, %14,3) öğrencilerinden tesadüfi yöntemle belirlenen 407 kişiden oluşan örneklem grubunun sihir, büyü ve tabiatüstü güçlerle ilgili tutumları nicel bir araştırmayla ortaya konulmaya çalışılmıştır. Araştırmada Frekans ve Chi-Square’den yararlanılmış olup, verilerin değerlendirilmesinde ve hesaplanmış değerlerin bulunmasında SPSS 16.0 istatistik paket programı kullanılmıştır. Araştırma sonucunda, cinsiyetin, fakülte türünün, akademik başarı düzeyinin, aile dindarlığı ve öznel dindarlık algılarının sihir, büyü ve tabiatüstü güçlere karşı tutumlarda etkili olduğu tespit edilmiştir.
Otomatik Konuşma Tanımaya Genel Bakış, Yaklaşımlar ve Zorluklar: Türkçe Konuşma Tanımanın Gelecekteki Yolu
Authors: OYUCU Saadin , SEVER Hayri , POLAT Hüseyin
Published: December 2019

İnsanlar
arasındaki en önemli iletişim yöntemi olan konuşmanın, bilgisayarlar tarafından
tanınması önemli bir çalışma alanıdır. Bu araştırma alanında farklı diller
temel alınarak birçok çalışma gerçekleştirilmiştir. Literatürdeki çalışmalar
konuşma tanıma teknolojilerinin başarımının artmasında önemli rol oynamıştır. Bu
çalışmada konuşma tanıma ile ilgili bir literatür taraması sunulmuş ve farklı
dillerde bu araştırma alanında kaydedilen ilerlemeler tartışılmıştır. Konuşma
tanıma sistemlerinde kullanılan veri setleri, özellik çıkarma yaklaşımları,
konuşma tanıma yöntemleri ve performans değerlendirme ölçütleri incelenerek
konuşma tanımanın gelişimi ve bu alandaki zorluklara odaklanılmıştır. Konuşma
tanıma alanında son zamanlarda yapılan çalışmaların olumsuz koşullara (çevre
gürültüsü, konuşmacıda ve dilde değişkenlik) karşı çok daha güçlü yöntemler
geliştirmeye odaklandığı izlenmiştir. Bu nedenle araştırma alanı olarak
genişleyen olumsuz koşullardaki konuşma tanıma ile ilgili yakın geçmişteki
gelişmelere yönelik genel bir bakış açısı sunulmuştur. Böylelikle olumsuz
koşullar altında gerçekleştirilen konuşma tanımadaki tıkanıklık ve zorlukları
aşabilmek için kullanılabilecek yöntemleri seçmede yardımcı olunması
amaçlanmıştır.  Ayrıca Türkçe konuşma
tanımada kullanılan ve iyi bilinen yöntemler karşılaştırılmıştır. Türkçe konuşma
tanımanın zorluğu ve bu zorlukların üstesinden gelebilmek için kullanılabilecek
uygun yöntemler irdelenmiştir. Buna bağlı olarak da Türkçe konuşma tanımanın
gelecekteki rotasına ilişkin bir değerlendirme ortaya konulmuştur.
Elektrikli Sürme Sistemlerinin Gerçek Zamanlı Döngüde Donanımsal Benzetimi ve Kalıcı mıknatıslı Bir Senkron Motor Sürücü Uygulaması
Authors: ERDOGAN Nuh
Published: December 2019

Döngüde
donanımsal benzetim (DDB), gerçek zamanlı benzetime imkân veren ve son yıllarda
hem araştırmada hem de endüstriyel ürün geliştirmede yaygın bir şekilde
kullanılan bir tekniktir. Bu yöntemde kullanılan benzeticiler gerçek zamanlı
benzetim gerçekleştirebilen platformlardır. Platformun seçimi, modelleme
esnekliği ile yüksek doğruluk oranlı sistem gerçek zaman davranışını elde etme
yönlerinden önemlidir. Bu çalışmada, elektrik sürme sistemlerinin benzetiminde
kullanılan DDB yapıları tanıtılmış, gerçek zamanlı DDB’yi gerçekleştirebilen
benzetim platformları karşılaştırılmalı incelenmiş ve elektrikli sürme
sistemleri uygulama alanlarına göre uygun platform önerilerinde bulunulmuştur.
Durum çalışmasında, örnek bir vektör kontrollü kalıcı mıknatıslı senkron motor
(KMSM) sürücüsünün gerçek zamanlı benzetimi 3.0 GHz’de çalışan Intel işlemci
çekirdeği ve bir SPARTAN-3 kullanıcı programlamalı kapı dizisi (FPGA) içeren,
paralel işleme izin veren karma bir platformda gerçekleştirilmiş ve gerçek
zamanlı benzetimde karşılaşılan meseleler tartışılmıştır. Sonuçlar, vektör
kontrollü bir KMSM sürücüsünün gerçek zamanlı DDB’sinin çok çekirdekli işlemci
ve FPGA içeren benzetici ile gerçekleştirilebileceğini göstermiştir. Sonuçlar
doğrultusunda, daha yoğun hesaplama içeren ve daha yüksek frekanslı
anahtarlamalı elemanlara sahip kontrol sistemlerinin DDB’si için uygun gerçek
zamanlı benzetici platform önerilerinde bulunulmuştur.
MoSe2 Tek Tabakasının Fe-Mn Atomları ve FeMn Nanoatom Kümesi İle Etkileşmesi
Authors: DEMİRKIRAN Ayşe
Published: December 2019

Son
yıllarda ilginç elektriksel ve optiksel özellikler sergileyen iki boyutlu yarı
iletken malzemeler üretilmiştir. Tek tabakalı malzemelerde elektronlar farklı
davranışlar gösterirler. Elektronlar tek tabakalı malzeme arasında hareket
ettikçe, iki boyutta tutulurlar ve farklı özellikler ortaya çıkmaktadır.

Bu
kapsamda; MoSe2 (molibden diselenad) tek tabakasının optimazasyon
sonucu kararlı yapısı, Linux işletim sistemi ve quantum espresso 3.2 programı
ile elde edilip üzerinde çalışıldı. Öncelikle Mo(Molibden) ve Se(selenyum)
atomlarının bağ uzunluklarını belirleyerek, kararlı durumdaki MoSe2
tek tabakası oluşturuldu. Bunun için kinetik enerji kesilme değeri, örgü değeri
ve k nokta değerleri belirlendi. MoSe2 tek tabakanın kararlı
yapısını elde ederek bağlanma enerjisini, bağ uzunluğunu belirledik. Belirlenen
kararlı yapı üzerine Fe, Mn atomları ile FeMn atom kümesinin tutunmasının olası
konfigürasyonları üzerinde çalışıldı. Bu konfigürasyonlar içerisinde en kararlı
olan yapılar gösterildi.

 

Fe-Mn
atomlarının nano kümeleri katalizörlerde ve nanoelektronik alanlarındaki
uygulamalarından dolayı önemli olduğundan MoSe2 tek tabakası ile Fe,
Mn atomları ve FeMn atom kümesi arasındaki etkileşme incelendi.
Değişken Enkesitli Açık Kanal Akımının Deneysel ve Sayısal Modellemesi
Authors: GÜMÜŞ Veysel , ŞİMŞEK Oğuz , BAL Şemsettin
Published: December 2019

Bu
çalışmada, açık kanal içerisinde daralma ve genişleme kesiti oluşturan trapez
başlıklı yapı ile etkileşimde bulunan akım, deneysel ve sayısal olarak
incelenmiştir. Deneysel çalışmalarda, hız alanı akustik doppler hız ölçer
(Acoustic Doppler Velocimeter-ADV) ve su yüzü profili ise limnimetre
kullanılarak ölçülmüştür. Sayısal modellemelerde Standart k- ε (SKE),
Renormalization Group k- ε (RNG), Realizeble k- ε (RKE), Standart k-ω (SKW),
Kayma gerilmesi taşınımı (Shear Stress Transport-SST), Reynolds gerilme modeli
(Reynolds Stress Model-RSM) ve Bağımsız Girdap Benzetimi (Detached-Eddy
Simulation-DES) ve Büyük Girdap Benzetimi (Large Eddy Simulation-LES) modelleri
kullanılarak, akım hız alanı ve su yüzü profili belirlenmiştir. Kullanılan
modellerin performansları, Ortalama Karesel Hata (OKH) ve Ortalama Mutlak
Göreceli Hata (OMGH) parametrelerine göre değerlendirilmiştir. Sayısal model
sonuçları üzerinde etkisinin olduğu bilinen hesaplama ağının analizinde Ağ
Yakınsama İndeksi (Grid Convergence Index-GCI) yöntemi, serbest su yüzünün
belirlenmesinde ise Akışkan Hacimleri Yöntemi (Volume of Fluids-VOF)
kullanılmıştır. Çalışma sonucunda, akım hız alanı ve serbest su yüzü profilinin
belirlenmesinde, DES modelinin kullanılan diğer modellere göre daha başarılı
sonuç verdiği belirlenmiştir.