bluuebunny/crossref_metadata_2025 huggingface dataset:
Improvisation as the Foundation of Flow in Music Education: Connections to Attitudes, Gender and Genre
Authors: Korošec Kaja , Bačilija Susić Blaženka , Habe Katarina
Published: September 2022

The aim of our study was to explore the connection between improvisation and flow. Data were collected from 252 tertiary music students from Slovenia and Croatia (121 male and 131 female musicians), who filled in The Questionnaire on Attitudes to Music Improvisation, The Inventory on Feelings associated with Music Improvisation, and the Work-related Flow Inventory. The results show that the female students have significantly more negative feelings and attitudes toward improvisation, and they experience less flow while improvising. Differences were even more pronounced when comparing students who only played classical music with those who played other genres, as well. Regression analysis showed that we can explain 71% of the variance in flow with attitudes toward improvisation.
Correlations and Regression of the Initial and Final Sound on Reading Words in the Slovenian Language
Authors: Ropič Kop Marija
Published: September 2022

The level of pupils’ acquired phonological awareness at the beginning of the 1st grade of primary school presupposes a high probability of ability to perform an initial reading. The purpose of the study was to check the correlation and regression between the initial and the final sound and reading words in the Slovenian language. Accordingly, 192 first-grade pupils were included in the sample. The purpose of the study was to check the correlation and regression between the initial and the final sound and reading of the words. The importance of the findings highlights the promotion of voice awareness in kindergarten.
Pionierinnen im Dickicht der psychoanalytischen Weiblichkeitstheorien
Authors: Grosz-Ganzoni Ita
Published: September 2022

Die Position der Frauen in der Psychoanalyse ist vielfältig: Es gab die berühmten Patientinnen. Es gab die Pionierinnen, die in gesellschaftlich schwierigen Zeiten ihren Weg zur Psychoanalyse finden mussten, was oft mit dem Verzicht auf ein eigenes Familienleben verbunden war. Und Psychoanalytikerinnen spielten in der kritischen Auseinandersetzung um die Weiblichkeitstheorien Freuds in den 1920er und 1930er Jahren eine zentrale Rolle. Durch das Naziregime und seine Folgen wurde auch diese legendäre Debatte brutal unterbrochen. 40 Jahre danach, mit dem Erstarken der Frauenbewegung in den 1970er Jahren, wurde der Diskurs um die Weiblichkeitstheorien in der Psychoanalyse wieder aufgenommen und weiterentwickelt. 1971 bekamen auch die Schweizer Frauen das Stimm- und Wahlrecht, und ich begann am PSZ die psychoanalytische Ausbildung und ging auch an die berühmten Veranstaltungen der sogenannten «Plattform», einer Gruppe linker, institutionskritischer, vor allem junger KollegInnen, von denen sich die meisten in psychoanalytischer Ausbildung befanden oder sich für die Psychoanalyse interessierten.

Freuds Konzepte der Triebentwicklung, zu der auch die Theorie des Penisneides und des Kastrationskomplexes der Frau gehörte, wurde damals nicht kritisch hinterfragt. Sie gehörten sozusagen zum undiskutierten gewachsenen Felsen der psychoanalytischen Theorie. Die bekannte argentinische Psychoanalytikerin Marie Langer war die erste Person, die am Seminar offen und deutlich diese Theorien in Frage stellte. Für mich bedeutete das eine Aufforderung (eine Erlaubnis?) zum Anders- und Weiterdenken. 1979/80 entstand eine erste Frauengruppe mit Goldy Parin. 1991 wurde der Arbeitskreis für feministische Psychoanalyse gegründet. Mit Psychoanalytikerinnen und psychoanalytisch orientierten Wissenschaftlerinnen aus Deutschland, Österreich und der Schweiz, die sich einmal im Jahr treffen, wird seitdem die Thematik erweitert und vertieft. Das kritische Bewusstsein um Weiblichkeits- und Genderthemen verankerte sich schliesslich auch im PSZ.
Die Schwangerschaft in der psychoanalytischen Ausbildung
Authors: Brenner Anna , Preis Victoria
Published: September 2022

Im vorliegenden Beitrag wird der Frage nachgegangen, inwiefern die eigene Schwangerschaft während der psychoanalytischen oder psychoanalytisch orientierten Ausbildung besonders herausfordernd und belastend ist. Trotz einer Zunahme der Präsenz der Thematik in Publikationen und an Weiterbildungsinstituten scheint dennoch ein Mangel an Informationen zur und Reflexion über die Situation der schwangeren Ausbildungskandidatin vorhanden zu sein. Um der Frage nach möglichen Gründen für den Mangel an Informationen und unzureichende Reflexion nachzugehen, wurden Gruppengespräche mit Frauen geführt, die während der Ausbildung schwanger wurden. Daraus wurden bedeutsame Aspekte herausgegriffen und als Themenblöcke zusammengefasst, diskutiert und in grössere, u. a. gesellschaftliche Zusammenhänge eingeordnet.
Impact of service-learning interventions on civic values in the COVID-19 era
Authors: Ruiz-Ordoñez Yolanda , Salcedo-Mateu Amparo , Moret-Tatay moret Carmen
Published: September 2022

The COVID-19 outbreak has brought about challenges to all fields, civic values included. The service-learning (SL) disciplines can offer a useful tool in this scenario, where human rights are most vulnerable. Given the need to face current challenges in university education, this study aimed to propose a pre–post analysis of an SL intervention for the Spanish University population during the COVID-19 outbreak. Ninety-two Spanish undergraduate psychology students participated in the study. The Values and Civic Attitudes (VAL-U) scale was employed for the pre–post assessment. The analyses were developed through Statistical Package for the Social Sciences 22 and Amos 18.0 modules. The results have shown an effect on civic values after an intervention. Therefore, the VAL-U scale might be considered a valuable tool for assessing resilience in Spanish-speaking university students’ SL in the post-COVID-19 era.
Keywords: Attitude, civic, COVID-19, pre–post, service-learning, values;
Relationship between prisoners’ self-awareness and stress problems related to psychological well-being and duration in prison
Authors: Melaku Sewagegn Mola , Hunde Tigist Shiferaw
Published: September 2022

Various studies have focused on prisoners’ self-awareness, stress and stress-coping problems, concerning their psychological and social well-being; however, they did not show detailed information about the differences in these variables concerning prisoners in Addis Ababa. This study aimed to address the relationship between components of psychological well-being and duration among prisoners in Addis Ababa’s Kality Correctional Centre. To meet this objective, the researcher selected 100 participants by using systematic random sampling techniques. A 5-point Likert-type scale questionnaire was used. The data were analysed through percentage, frequency and correlation. The result revealed that there is no significant relationship between components of psychological well-being and age among prisoners. However, the study revealed that there is a significant difference between male and female prisoners in the components of psychological well-being.
Keywords: Prisoners, self-awareness, stress, psychological well-being;
Performance Comparison of Neural Network-Based Models in the Classification of Polycystic Ovary Syndrome Disease
Authors: KÜÇÜKAKÇALI Zeynep , YAĞIN Fatma Hilal , BALIKÇI ÇİÇEK İpek
Published: September 2022

In this study, it was aimed to compare the performances of the above mentioned ANN, MLP and deep learning methods to determine polycystic ovary syndrome (PCOS) risk factors and predict PCOS diagnosis. In this study, the data set “Polycystic ovary syndrome” was used to determine PCOS risk factors and to compare the performances of ANN, MLP and deep learning methods for PCOS diagnosis prediction. The performance of the models was evaluated with accuracy, sensitivity, specificity, positive/negative predictive values. Factors associated with PCOS were estimated from the deep learning model that has the best performance. Accuracy, sensitivity, specificity, positive predictive value and negative predictive value obtained from the MLP method were 87.25%, 79.66%, 90.93%, 81.03%, and 90.19%. Accuracy, sensitivity, specificity, positive predictive value and negative predictive value obtained from the Neural Network method were 87.80%, 79.10%, 92.03%, 82.84%, and 90.05%. Accuracy, sensitivity, specificity, positive predictive value and negative predictive value obtained from the Deep Learning method were 89.09%, 81.92%, 92.58%, 84.30%, and 91.33%. According to the findings obtained from this study, the best classification result according to the performance metrics obtained from the artificial neural networks, MLP and deep learning methods used for the PCOS data set used in the study belongs to the deep learning method. As a result, PCOS was successfully classified in the light of the findings obtained from the study, and clinical findings were tried to be revealed by giving the risk factors associated with PCOS.
Pürülan Enfeksiyöz Miyozit
Authors: ŞAHİNOĞLU Mustafa Serhat , ALKAN Sevil
Published: September 2022

Pürülan enfeksiyöz miyozit; deri ve yumuşak doku enfeksiyonları sınıfındadır ve eskiden sadece tropikal bölgelerden bildirilmiş olduğundan tropikal miyozit olarak tanımlanan bir hastalıktır. Daha önceleri olguların genç erkeklerde gelişen bir hastalık olduğu düşünülmekteydi ancak hastalığa dair farkındalığın artması ile farklı teoriler ortaya çıkmış ve dünya genelinden ve tüm yaş gruplarından (çocuklar ve yaşlılar dahil) olgular bildirilmiştir. Bu hastalık çizgili kasların inflamasyonudur. Primer veya sekonder olarak gelişebilir. En sık etkeni cilt flora üyesi olan Staphylococcus aureus olmakla birlikte immunsupresif olgularda veya sekonder olgularda çok farklı etkenlerin bu hastalığa sebep olduğu bildirilmiştir. Bu derleme çalışmasında, pürülan enfeksiyöz miyozite neden olan çeşitli patojenler, tanı ve tedavi yöntemleri tartışılmaktadır.
Effect of glucagon-like peptide-1 on differentiation of adipose derived mesenchymal stem cells into cardiomyocytes
Authors: TEKİN Özgür , UYANIKGİL Yiğit , TAŞKIRAN Dilek
Published: September 2022

Aim: Mesenchymal stem cells can easily differentiate into cardiomyocytes in vitro conditions using
various protocols. However, the agents used in these protocols have been reported to have some
adverse effects on cell viability. Azacitidine is used to differentiate mesenchymal stem cells into cardiac
muscle cells. The aim of the present study was to investigate the effects of Exenatide a GLP-1 receptor
agonist, on differentiation and viability of human adipose tissue derived stem cells into cardiomyocytes.
Materials and Methods: The effects of Azacytidine and Exenatide on cell viability and proliferation of
human adipose tissue derived stem cells were analyzed with cytotoxicity assay. For differentiation
procedure, of human adipose tissue derived stem cells were incubated with Azacytidine and Exenatide
through four weeks. The morphological alterations of human adipose tissue derived stem cells were
monitored and the expressions of cardiomyogenic differentiation markers (cTnI, GATA4 ve MYH7) were
evaluated immunohistochemically. Also, cardiac troponin I (cTnI) levels in the cultures were measured
using enzyme-linked immunosorbent assay. Results were evaluated by one way analysis of variance
(ANOVA) and post-hoc test.
Results: Treatment of the human adipose tissue derived stem cells with Azacytidine significantly
decreased cell viability (54.4%) compared to control whereas treatment of cells with Azacytidine +
Exenatide prevented cell death in a dose-dependent manner. Cells treated with Azacytidine and
Exenatide showed significant morphological alterations consistent with cardiyomyogenic differentiation,
and increase in expression cardiomyogenic markers. cTnI levels were found significantly higher in
cultures treated separately and together with Azacytidine and Exenatide compared to control.
Conclusion: Overall, these findings suggested that GLP-1 receptor agonist Exenatide may have
beneficial effects on cardiomyogenic differention of human adipose tissue derived stem cells by
reducing cell damage caused by Azacytidine.
War in Minds. Review of the book by Maciej Gorny “Welka wojna profesorow. Nauki o czlowieku (1912–1923)” [Russ. ed.: M. Gurnyi «Velikaya voina professorov. Gumanitarnye nauki. 1912–1923»]
Authors: Vaganov Andrey
Published: September 2022

The fundamental research of Maciej Gurny, professor at the Institute of History of the Polish Academy of Sciences in Berlin, is reviewed. Professor Gurny’s book is devoted to a phenomenon known in the historiography of the 20th century as “Krieg der Geister”. This seemingly invisible and bloodless war belongs only to the sphere of ideas. However, the scientific forces that were involved in this “Krieg der Geister”, as the author shows, directly influenced the origins, the course, and the consequences of the hot war – the World War I. These spheres are geography, racial anthropology, psychology and psychiatry. The monograph shows the role of the intellectuals of the region of Central-Eastern Europe and the Balkans in mobilizing the ideological (moral) and material resources of the warring countries. Having processed a huge array of information (about 1000 references to sources), M. Gurny notices a number of very interesting nuances in the topic under study. At the same time, one of the shortcomings of the book, in the opinion of the reviewer, is the absolutely insufficient use of Russian sources devoted to the phenomenon of “Krieg der Geister”. And those exist in not small numbers. One can argue with many of the conclusions that M. Gurny makes, but one of the undoubted advantages of the monograph is the return to the Russian intellectual space of many forgotten, but, paradoxically, historical plots that are relevant today.
Innovations in the System of Higher Education
Authors: Chulkova Galina
Published: September 2022

The article is devoted to the objects of innovative infrastructure in the education system, which are designed to create conditions for the implementation of innovative projects and programs that are essential for the development of the education system in the Russian Federation. Organizations implementing innovative projects and programs are recognized as regional or federal innovation platforms. Moscow State Pedagogical University is working to create an innovative educational system and methodological mechanisms based on the active immersion of students in scientific and technological research, and providing a new level of quality in physical education for schoolchildren and training of physicists. The introduction of the results of the study into the process of preparing a university graduate to work in a modern school will allow him to form new types of professional activities that are in demand by society at the present time, and successfully solve the tasks set for the education system,including teaching physics. The model can be broadcast and replicated in any region of the Russian Federation. Ensuring the effective operation of new educational programs, educational technologies, mechanisms, forms and methods of education management is due to the opportunities provided by associations of universities with innovative companies.
Nuovi farmaci per nuovi bisogni: dagli studi di fase II ad oggi.
Authors: Cerchiaro Matteo , al. et
Published: September 2022

L’ART ha reso l’HIV una malattia cronica e questo ha cambiato i bisogni delle persone che vivono con HIV (PLWH). Negli ultimi anni nuovi farmaci antiretrovirali sono stati approvati o sono in fase di approvazione.
In particolare, fostemsavir e ibalizumab sono stati approvati nel paziente heavily treatment experienced (HTE), cabotegravir e rilpivirina long acting nel paziente in semplificazione; infine, lenacapavir, un inibitore del capside, è appena stato approvato come farmaco long acting nel paziente HTE.
I farmaci in corso di approvazione sono islatravir, un inibitore nucleosidico della traslocazione trascrittasi inversa, MI 254 e MI 937, ovvero inibitori della maturazione, e altri anticorpi monoclonali.
Nel prossimo futuro saranno tante le novità proposte e gli scenari che si apriranno per le PLWH.
Effect of Recurring Expenditure Financed by External Grants on Promoting Sustainable Economic Development of Sub-Saharan Africa Countries
Authors: Chindengwike James
Published: September 2022

This study examined the effect of recurring expenditure financed by external grants on sustainable economic development of sub - Saharan Africa Countries. This paper asked the participation of external grants on the recurring expenditure as one of the source of funds, separately from international finance perspective; the mechanism of domestic did not talk about. This paper filled this gap in literature by determining the recurring expenditure financed by external grants. The study adopted a time series research design where by secondary data were used. The population of the study was external grants and Gross Domestic Product (GDP) from 1988/89 - 2019/20 financial years (Annual Data). The sample size of the research was 32 observations. Purposive sampling was used to choose the Tanzania as a study area of the research; data were collected from the Organization for Economic Co-operation and Development (OECD).The parameters tests such as test for co integration and unit root test was used to investigate co-integrating vectors. After that, Autoregressive Distributive Lag Model (ARDL) was carrying out to find the results. The finding shows that, recurring expenditure financed by external grants influence sustainable economic development; with P- Value of 0.002. At the same time as inflation rate looks to be insignificant with P- Value of 0.719. The study recommends in order encouraging sustainable economic development, government must proceed to promote the relationship with nations by giving development programs which are consistent with supporting programs. additionally, the research predict the requirement for introducing strong policies that will assist and promote strong collaboration with donor nations and spend more in substantial speculation and utilization expenditure in order  to increase the level of production as which will affect the sustainable economic development.
Una società che si racconta
Authors: Antonelli Quinto
Published: September 2022

Per il suo radicamento locale, l’Archivio della scrittura popolare di Trento ha avuto una storia molto specifica. Ha assunto, dapprima, le funzioni di un «contro-archivio» (raccogliere e conservare le scritture delle classi sociali subalterne), rimanendo tuttavia anche il luogo della memoria della minoranza italiana all’epoca dell’impero asburgico. Ha accolto in seguito i piccoli archivi famigliari con le tante scritture legate alla casa (perlopiù contadina). E infine, con il deposito delle lettere delle ammiratrici e ammiratori della cantante Gigliola Cinquetti, è diventato un archivio d’importanza nazionale, superando, nella qualità delle scritture raccolte, anche la definizione così connotativa di «popolare».
Predictor Prognosis of Pediatric Septic Shock : Literature review
Authors: Rosida Nikma Alfi , Meilyana Berna Detha , Riswanto Rischar Beny , Suhendra Suhendra
Published: September 2022

Introduction: The unpredictability of body response to organ dysfunction needs an effective tool to predict the prognosis of shock septic. Early recognition and treatment of septic shock improved prognosis and reduced mortality, especially in pediatrics. This review aimed to identify the predictor of mortality in pediatric septic shock.

Methods: We performed a literature review of the predictor of mortality in pediatric septic shock conducted between 2015 and 2020 in ProQuest, Google Scholar, PubMed, and Science Direct. We used keywords (predictor or predictive) and (septic shock or septic), and (prognostic or prognosis) and (pediatric or children). The study selection was using the Preferred Reporting Items for Systematic Review and Meta-Analysis PRISMA framework.

Results: 944 articles identified in ProQuest, 720 articles in Science Direct, 339 articles in Google Scholar, and 67 in Pubmed. Equally, the total articles were 2,070 articles, and there were 414 duplicates. After review of the complete texts was performed for 35 potential studies. In the full-text review, we excluded review articles (n = 3), different populations (n=8), and of poor quality (n = 20). Eventually, four papers were reviewed in this study. We found PELOD, PELOD-2, PIM, PIM 2, PIM 3, PMODS, PRISM, PRISM-III, PRISM-IV, and pSOFA as a predictor of sepsis in pediatrics.

Conclusion:
In conclusion, pSOFA is a more accurate screening result for estimating the risk of death by being 10 times more sensitive and specific. However, adding biomarkers to pSOFA will improve the accuracy of the predictor prognosis of pediatric sepsis.
Effect of Sesame Oil Addition during Olive Oil Deep-frying
Authors: Ioannou Evangelia , Georgiou Constantinos
Published: September 2022

Fresh potatoes were deep-fried in olive oil (OO) & extra virgin olive oil (EVOO) and their blends with 5%, 10% and 20% v/v sesame oil (SO). This is the first report on the use of sesame oil as natural source of antioxidant for olive oil deep-frying. Oil was evaluated for Peroxide Value (PV), Free Fatty Acids (FFA), K232, K270, Trolox Equivalent Antioxidant Capacity (TEAC) and Total Phenols (TP) until Total Polar Compounds (TPCs) reached 25%. Sesame lignan transformations were monitored through Reverse-phase HPLC. While TPCs in olive oils increased at a steady rate, the addition of 5%, 10% and 20% v/v SO created a time window lasting 1, 2 and 3 hours, respectively, where TPCs were constant. SO addition to OO increased the total frying time. Furthermore, the addition of SO reduced the peroxides formation rate for both OO and EVOO. EVOO was more resistant to oxidation than OO as measured by TPCs and TEAC, while frying time raised from 21.5 to 25.25 h when EVOO replaced OO. The increase in frying time for olive oil but not for extra virgin olive oil, after SO addition, is pointing out a niche market for extra virgin olive oil in deep-frying.
Can Atomic Theories Be Evaluated in Terms of Paradigm Shift?
Authors: BAŞARAN Vural , GÖZÜTOK Tarık Tuna
Published: September 2022

Atom is one of the most controversial and interesting subjects of first natural philosophy and natural sciences. It has preoccupied people's minds since ancient times. This historical adventure, which started with the ancient Greek atomism and Muslim scholars in the Middle Ages also contributed to ideas of atom. Since atomism was far from the possibilities of experimentation in the early periods, it was tried to be proved by rational reasoning. XIX. In the 19th century, the concept of the atom has become one of the fundamental phenomena of modern science. By the 20th century, it was understood that this fundamental particle, which was thought to be indivisible, could be divided into more fundamental parts, thanks to both experimental evidence and scientific and technological developments. In fact, thanks to the atom, energies that could not even be imagined before having begun to be obtained.

In our study, first, this journey of the atom will be discussed. Later, the Kuhnian approach, which deeply affected the history of science studies in the second half of the 20th century, will be examined. For this, the concepts of paradigm and non-comparability will be discussed. Then, the place of this Kuhnian approach in the history of the atom, which is given in the first part of the study, will be discussed. The Kuhnian paradigm was frequently used by Kuhn and his followers, especially in explanations in the history of astronomy. In our study, it will be shown in the explanatory power of this approach is weak when the atomic history is examined.
Social Orphanhood in Contemporary Ukrainian Literature for Children and Young People
Authors: Kachak Tetiana
Published: September 2022

The artistic interpretation of the theme of social orphanhood in contemporary literature for children and young people is a reaction by writers to social phenomena affecting the child. In this article, I explore the artistic representation of social orphanhood in contemporary Ukrainian literature for children and young people. I note that the works of Ukrainian writers complement the tradition of depicting orphans in world literature. The paper goes on to analyse the plots of works about children who become social orphans as a result of the labour migration of parents, to define a range of issues raised within this topic considering the images of orphans, and to derive a typology based on an analysis of their behavioural patterns. The common and distinctive features of the poetics of works on orphaned childhood are noted, and images are presented of orphans in Ukrainian and world literature, taking into account the results of research by Melanie A. Kimball, Claudia Mills, and Dirk P. Mattson.
Creating Social Reality by Soviet Children's Publishing Companies in Ukraine in the 1920s and 1930s
Authors: Zhygun Snizhana
Published: September 2022

The article deals with the influence of state ideology on children, as carried out through state control/supervision of book publishing. The purpose of this study is to demonstrate the peculiarities of creating (a new) social reality by means of children’s literature in the 1920s and 1930s in Ukraine. The research material is a selection of publications of the Ukrainian specialised publishing houses Ditvydav and Molodyi Bilshovyk. The results of the analysis show that 46% of the books in the corpus contain the following keywords: revolution, civil war, Pioneers, Little Octobrists, Soviet holidays, Lenin, Stalin, collective farms, collectivisation, industrialisation, metallurgy, factory, mines, and so forth, that is, they contain an emphasised ideological component. Soviet society’s rejection of the national tradition, even in the face of the policy of Ukrainianisation, is also confirmed. The dominance of Russia and its representatives in comparison with other republics in the USSR and the limitations of gender roles in the constructed worldview are also demonstrated.
Self-Made Men – Architects of the Self: the New Houses and New Landscapes of the Western Balkans
Authors: Haluzík Radan
Published: September 2022

As a consequence of economic globalisation, the Western Balkans has been experiencing massive boom in the building of houses. In rural and mountain parts of the former Yugoslavia, in some of the least expected locations, often in areas inhabited by ethnic minorities, many imposing houses have been constructed. These are often bigger and more extravagant than their models in western European suburbs and have been built largely on the basis of remittances from migrants in the EU or USA. It is not just “remittance houses” but whole new “remittance landscapes” that have come into being. This article explores the elemental spontaneity of this building boom. Many of the houses concerned have been built without project plans, architects or building permission and the new suburbs are developing without urban planning or infrastructure. I try to show some of the predictable but, above all, unexpected connections and results of the absence of rationalist planning and budgeting.
Role sborů pro občanské záležitosti v rozšiřování občanských pohřebních obřadů
Authors: Nešporová Olga
Published: September 2022

Článek popisuje historii sborů pro občanské záležitosti v české části bývalého Československa v 50. až 80. letech 20 století. Využity byly dva hlavní datové zdroje. Prvním byl hloubkové rozhovory s pohřebními profesionály, někdy zároveň členy sborů pro občanské záležitosti, kteří realizovali pohřební obřady ve sledovaném období. Druhým byly příručky pro pohřební profesionály a civilní pohřební řečníky o pohřebních proslovech a náležité formě občanských (socialistických) pohřebních obřadů. Autorka ukazuje, že členové sborů pro občanské záležitosti aktivně utvářeli nové formy obřadů a sbory pro občanské záležitosti hrály ústřední roli v rozšiřování občanských pohřbů na území dnešní České republiky. Sbory byly hierarchicky uspořádané a centrálně organizované a v jejich aktivitě byly ohromné regionální rozdíly. Na konci 70. let a v 80. letech 20. století byly aktivnější na Moravě, tedy tam, kde byly počty občanských pohřbů nižší, a proto tam byla potřeba pro jejich propagaci silnější.
Prediction and Identification of Gas Hydrates Formation and Reformation in Vertical and Inclined Gas Wells
Authors: Landjobo Pagou Arnold , Guo Xiao , Peng Long , AkhayieMamat Abdoulaye
Published: September 2022

Natural gas hydrate is one of the most promising prospective energy sources which may help alleviate future oil and gas shortages. Natural gas hydrate reformation in gas wells or transportation equipment is a significant concern. It reduces the gas production rate. An exceptionally high reformation rate can drastically reduce productivity and completely plug the equipment. This may result in equipment damage and cause the operating company to abandon the well, resulting in considerable financial losses. In some instances, this may result in staff loss. Consequently, early detection and prediction of natural gas hydrate reformation are essential for the operating companies to avoid lives and financial losses.

This research assumes that hydrate reformation happens gradually in the tubing due to the nucleation of the hydrate slurry adhering to the tubing wall, the natural gas, and the hydrate particle. In this study, we develop the reformed hydrate thickness and the critical gas velocity correlations under the annular flow assumption and several others by establishing the Navier Stokes equation of the Newtonian fluid (gas phase) and non-Newtonian fluid (natural gas hydrate slurry). Consequently, the model developed accounts for the effects of the well's inclination angle, circumferential angle, and tubing diameter. It also incorporates the gas flow rate, pressure, temperature, well characteristics and fluid rheology.

A published gas field data set is utilized to validate the developed model under 10%, 30%, 50%, 70%, and 100% natural gas hydrate void fractions in the tubing. As a result, as the reformed gas hydrate volume increases in the well section, the gas flow rate and the formation pressure increase. Our findings also indicate that the inclination angle, tubing diameter, circumferential angle, temperature, and pressure are statistically the most influential natural gas hydrate reformation factors. Furthermore, the analysis of variance (ANOVA) highlights some significant interactions contributing to the natural gas hydrate reformation, such as tube diameter-inclination angle, temperature-pressure, tube diameter-temperature-pressure, inclination angle-temperature-pressure.
Adsorption of Aminopolycarboxylic Acids in Carbonate Formations
Authors: Gasimli Nijat , Mahmoud Mohamed , Hassan Amjed , Shahzad Kamal Muhammed , Patil Shirish , Al-Abdrabalnabi Ridha
Published: September 2022

Numerous well operations, including water injection, varying stimulation approaches, and enhanced oil recovery (EOR) techniques are implemented during the production period in order to maintain the longevity of hydrocarbon production. However, reservoir formation, production, and injection facilities are often impacted by these treatments. Well operations induce inorganic scale to form near-wellbore regions and in various production and injection structures. Consequently, the deposition of scales hinders assessing an optimum hydrocarbon production as their precipitation on formation, various surface, and downhole equipment leads to many problems, including pressure decrement, formation damage, and operational failure of subsurface equipment.

As a control measure to prevent scale precipitation downhole squeeze treatment is commonly used in the petroleum industry. By applying a squeeze treatment, a scale inhibitor solution is introduced into a formation above the formation pressure, allowing the scale inhibitor to get into the deep into near-wellbore formation. Downhole squeezing allows scale inhibitors to adsorb on the internal rock surface to avoid the settling down of scale precipitates. Thus, the study of adsorption of different types of inhibitors, such as chelating agents, polymeric inhibitors, and polyphosphates on formation is becoming necessary. The study incorporated several experimental techniques, including dynamic adsorption experiments using coreflooding setup, ICP-OES (Inductively Coupled Plasma - Optical Emission Spectrometry), and ζ-potential measurements targeting evaluation of adsorption of aminopolycarboxylic acids in carbonate rocks and iron precipitation in calcite mineral. Potential precipitation of iron in varying pH environments and causing the formation of iron-containing scales was assessed through ζ-potential measurements.

The findings reveal that the concentration of aminopolycarboxylic acids plays a significant role in their adsorption on carbonate rocks. The adsorption is also affected by different factors, such as the presence of salts. The results of ζ-potential measurements showed that iron (II) and iron (III) precipitation is controlled by the pH environment in calcite minerals. The treatments with 20 wt% ethylenediaminetetraacetic acid (EDTA) and diethylenetriamine pentaacetate acid (DTPA) produced the highest adsorption capacity in carbonate rock samples by inhibiting 84% and 85% of iron (III) ions, respectively. The encountered permeability damage in the adsorption tests was between 25% and 32%. Moreover, the presence of the salts considerably decreased the adsorption of EDTA and caused almost 20% more permeability reduction.

Unlike the conventional testing methods for inhibitor adsorption, a novel experimental setup, coreflooding was used during the inhibitor adsorption, and scale inhibition in carbonate formation.
Exploring the Nature of the Fine-Structure Constant in the Setting of General Relativity, Quantum Physics, and the Evolution of the Universe
Authors: Williams Lamont
Published: September 2022

This study explores the possibility that the value of the fine-structure constant, α, is linked to the spacetime geometry of the electromagnetic field between two elementary charges, connecting the smooth manifold responsible for gravity with the discreteness of the electromagnetic field. In a step-by-step manner, the study presents a logical basis for the establishment of a fundamental equation for α. It is shown that the equation is directly linked to experimental data involving elementary electric charge, e, and resolves the problems of the Landau pole (when the value of e is infinite at a finite energy level) and triviality (when the value of e is zero at an infinite energy level) in quantum electrodynamics. The equation is also consistent with the evolution of the universe—here, a near-perfect match exists between specific points along the line representing the running of the constant’s value by way of the equation and important periods in the universe’s development. The presented concepts have the potential to assist in efforts to determine how the value of α might be directly derived within the Standard Model.
Multi-view Support Vector Machines with Sub-view Learning
Authors: Hao Qi , Zheng Wenguang , Xiao Yingyuan , Zhu Wenxin
Published: September 2022

Multi-view learning improves the performance of existing learning tasks by using complementary information between multiple feature sets. In the latest research, multi-view learning model using privilege information is proposed, specific models such as PSVM-2V and MCPK. In these models, views complement each other by acting as privileged information policies, However, a single view contains privilege information that can guide the classifier, and the existing framework does not consider it. In order to use this information to correct multi-view support vector machine classifier, we propose a framework for generating a series of small-scale views based on information hidden in a single view, which extends the original multi-view parallel structure to a hierarchical structure with sub-view mechanism. In this paper, two sub-view learning structures SL-PSVM-2V and SL-MCPK are constructed. The two new models fully exploit the data features in the view. Similarly, they follow the principles of consistency and complementarity. We use the standard quadratic programming solver to solve the new model. In 55 groups of classification experiments and noise sensitivity tests, the new model has better performance than the benchmark model. Statistical comparison shows that the new method is significantly different from the existing methods.
Hematological and biochemical reference intervals of wild-caught and inhouse adult Indian rhesus macaques
Authors: Shah Niraj , Bhatt Laxit , Patel Rajesh , Patel Tushar , Patel Nayankumar , Trivedi Harshida , Patel Nilam , Patel Jitendra , Patel Satish , Sundar Rajesh , Jain Mukul
Published: September 2022

Background Nonhuman primates are essentially used for research purposes such as studying diseases, different biological processes and in drug discovery and development programs. Various clinical pathology parameters are used as biomarkers of disease conditions in biomedical research. Detailed reports of these parameters are not available for Indian-origin rhesus macaques. In order to meet the increasing need of information, we conducted this study on 121 adult Indian rhesus macaques (57 wild-sourced and 64 inhouse animals, aged 3-7 years). A total of 18 hematology and 18 biochemistry parameters were evaluated and reported in this study. Data from these parameters were statistically evaluated for significance amongst inhouse and wild-born animals and for difference amongst sexes. Reference range was calculated according to C28-A3 guidelines for reporting reference intervals of clinical laboratory parameters.
Results: Source of the animals and sex appeared to have statistically significant effects on reference values and range. Wild-born animals reported higher WBC, platelets, neutrophils, RBC, hemoglobin, HCT, MCV and total protein values in comparison to inhouse monkeys. Sex-based differences were observed for parameters such as RBCs, hemoglobin, HCT, creatinine, calcium, phosphorus, albumin and total protein amongst others.
Conclusions: Through this study, we have established a comprehensive data set of reference values and intervals for certain hematological and biochemical parameters which will help researchers in planning, conducting and interpreting various aspects of biomedical research employing Indian-origin rhesus monkeys.
Seasonal Variation of Water quality and Heavy Metal Pollution Index of 5 Ponds of Raipur City, India
Authors: Dash Diptimayee , Mishra Hemanta Kumar , Pattanaik S K
Published: September 2022

The authors have requested that this preprint be removed from Research Square.
A school-integrated physical exercise program improves motor performance of children and adolescents
Authors: Homeyer Denise , Dagdar Nima Memaran , Kück Momme , Grams Lena , Born Jeannine von der , Bauer Elena , Schwalba Martina , Kerling Arno , von Maltzahn Nadine , Albrecht Alexander , Haverich Axel , Stiesch Meike , Melk Anette , Tegtbur Uwe
Published: September 2022

Purpose Children’s sedentary time has increased in recent years, especially during school, while daily physical activity has decreased. The lack of physical activity can contribute to a deterioration in motor performance, which is key to a healthy development. We implemented a comprehensive exercise program in the school setting. Our study aimed to evaluate this program by assessing changes in motor skills after one year and to compare these changes to children who did not participate. Methods A total of 357 children from 5 schools were included in this observational longitudinal cohort study. Motor skills were assessed using the German Motor Test 6–18. Children were either assigned to the exercise group (EG) or waiting group (WG). The EG participated in the physical activity program for one year. Of those, a total of 303 children (EG n = 183; WG n = 120) completed motor tests at baseline and follow-up one year later, and comprise the study population. Linear mixed modeling was used to calculate corrected means and analyze for inter-group differences of change in motor skills after one year between the groups, and to determine the effect of sex, age group and weight category on the change in motor skills. Results After one year of additional physical activity, the EG improved significantly more strongly in 6 out of 8 motor skill tests than the WG. After the adjustment for sex, age, and BMI the improvement is still significantly stronger in the EG in 4 of 8 motor skill tests (sprint, side jumps, both p = 0.017; stand and reach, p = 0.012; ergometry, p = < 0.001), when compared to the WG. Girls improved more strongly in the sit-ups than boys, 2nd graders more than 5th graders in the backwards balance and the ergometry, non-overweight pupils more in the standing long jump than overweight children. Conclusions Participating in the exercise program for one year positively influenced motor skill development in schoolchildren. Our data suggest that girls were not disadvantaged, and even improved more than boys in the sit-ups, and that overweight pupils profited as much as their non-overweight peers in all categories but one. The exercise program, simple and easily implemented into the school routine, is effective in increasing motor skills and physical fitness.
The Anticancer Effect of Zuojinwan on Gastric Cancer Through Multiple Signaling Pathway via miR-107/RUNX1T1 Axis
Authors: he bin , Rao Qi , Li Ruochan , peng xinyi , Xu Yundan , Zhao Gang
Published: September 2022

Background: Zuojinwan (ZJW), a famous Chinese medicine formula, has been widely used to treat gastric cancer (GC) which is the third leading cause of cancer-related death around the world.miR-107, a kind of small non-coding RNAs, play a vital role in the occurrence and development of GC.
Aim:A network pharmacology-based strategy combined with in vitro and in vivo experiment were employed to investigate the anticancer effect, potential targets, and molecular mechanism of ZJW against GC by miR-107.
Methods:Potential targets and signaling pathways of ZJW to treating gastric cancerby miR-107 were determined usingbioinformatics analysis from public databases.
miR-107 and its downstream protein expression levels in GC tissues and cell lines were detected by real-time reverse transcription polymerase chain reaction (RT-PCR)
or western blot,which were further confirmed by Luciferase reporter assay and
Pearson correlation test.The anticancer effect of ZJW in vitro and in vivo were examined by Nude mouse xenograft tumor model and MGC-803 cells. The possible antitumor mechanism of ZJW was studied by using western blot analysis.
Results:A total of 33 bioactive ingredients and 147 gene targets of ZJW acting on GC by miR-107 were identified. The miR-107 level was reduced and RUNX1T1 was down-expressed in GC samples.The expression of target was positively correlated with miR-107 in patients with GC.RUNX1T1 was targeted by miR-107.Since overexpression of miR-107 significantly decreased RUNX1T1 expression in MGC-803 cells, and knockdown of miR-107 enhanced RUNX1T1 expression. ZJW inhibited MGC-803 cells proliferation in dose- and time-dependent manner by activating PI3K/AKT/mTOR pathway and arresting the cell cycle in S phase through regulating the expression of Cyclin A, Cyclin B1 and Cyclin E. ZJW suppressed MGC-803 cells migration in dose-dependent manner by increasing E-cadherin expression. ZJW induced MGC-803 cells apoptosis by Fas death receptor and Bcl-2/Bax pathway. Tumor growth was attenuated by ZJW in nude mouse.miR-107 expression was downregulated in ZJW-treated group compared with untreated group, while the protein expression of RUNX1T1 was upregulated.
Conclusions: showed significant anti-tumor activity against gastric cancer MGC-803 cells through multiple signaling pathways via miR-107/RUNX1T1 axis both in vitro and in vivo.
Retinex-Based Light Source Generation for Relighting up Night Photography
Authors: Oishi Sou , Fukushima Norishige
Published: September 2022

The lighting up of buildings is one of the entertainments that make a city more colorful, and photographer sometimes changes the lighting by using photo-editing applications. This paper proposes a method for automatically performing such an application that follows the Retinex theory. The Retinex theory indicates that the complex scenes caught by the human visual system are decomposed into illumination and reflectance components. Many Retinex-based applications take much cost into the decomposition, while we show that the decomposition accuracy is less dependent on the final output for the nightscape relighting. First, we propose an extracting method of a relighting saliency map using Retinex with edge-preserving filtering. Second, we propose a sampling method to specify the lighting area in the limited area. We show that relighting within the limited area can be represented without illumination and reflectance decomposition. We then show that this fact can be exploited to realize this application using a simple Retinex decomposition of the single-scale Retinex with fast edge-preserving filters to represent various lighting effects. Experimental results show that the proposed sampling method is successful in keeping the illuminated points in bright locations and equally spaced.Also, the proposed various diffusion method can enhance night skyline photographs with various expressions. Our code and dataset are available at https://github.com/norishigefukushima/RelightingUpNightPhotography.
How to coordinate China's regional low-carbon digital economy with economic and social development: a composite system synergy perspective
Authors: Xing Zeyu , Huang Jing , Wang Jing
Published: September 2022

This paper creatively puts forward the theory of low-carbon digital economy from the perspective of resource flow, digital flow and energy flow, and studies the synergy effect of low-carbon digital development by constructing the synergy model of low-carbon digital development economic and social development. Based on theoretical research, this paper constructs a synergy model and evaluation index system between low-carbon digital development and economic and social development, and an empirical analysis was conducted based on data related to regional low-carbon digital development and economic and social development in China from 2014 to 2019. The empirical results show that the development of China's low-carbon digital economy is the main driving force for future economic and social development. Further, if the low carbon economy and the digital economy included in the stimulus policies can play a synergistic role,It will be able to play the greatest role in promoting economic and social development. And such a scenario is used as a practice in different regions of China in future. The research conclusion of this paper expands the theoretical system of low-carbon economy and digital economy, provides theoretical support for the path design of regional low-carbon digital economy development in China, and enriches the discussion on the construction of ecological civilization and the construction of a community with a common future for mankind.