bluuebunny/crossref_metadata_2025 huggingface dataset:
Dual lumen cannulation and mobilization of patients with venovenous extracorporeal membrane oxygenation
Authors: Noe Christian , Rottmann Felix A. , Bemtgen Xavier , Supady Alexander , Wengenmayer Tobias , Staudacher Dawid L.
Published: June 2023

Background

Mobilization is important in longer courses in intensive care unit (ICU), typical for patients requiring venovenous extracorporeal membrane oxygenation (V‐V ECMO). For patients supported with ECMO, especially out‐of‐bed mobilizations improve outcome. We hypothesized that utilization of a dual lumen cannula (DLC) for V‐V ECMO would facilitate out‐of‐bed mobilization compared to single lumen cannulas (SLC).

Methods

Retrospective single center registry study including all V‐V ECMO patients cannulated between 10/2010 and 05/2021 for respiratory failure.

Results

The registry included 355 V‐V ECMO patients (median age 55.6 years, 31.8% female, 27.3% with preexisting pulmonary disease), 289/355 (81.4%) primary cannulated with DLC, and 66/355 (18.6%) using SLC. Both groups had similar pre‐ECMO characteristics. The runtime of the first ECMO cannula was significantly longer in DLC compared to SLC (169 vs. 115 h, p = 0.015). The frequency of prone positioning during V‐V ECMO was similar in both groups (38.4 vs. 34.8%, p = 0.673). There was no difference in in‐bed mobilization (41.2 vs. 36.4%, for DLC and SLC, respectively, p = 0.491). Patients with DLC were more often mobilized out‐of‐bed (25.6 vs. 12.1%, OR 2.495 [95% CI 1.150 to 5.268], for DLC and SLC, respectively, p = 0.023). Hospital survival was similar in both groups (46.4 vs. 39.4%, for DLC and SLC, respectively, p = 0.339).

Conclusion

Patients cannulated with a dual lumen cannula for V‐V ECMO support were significantly more often mobilized out‐of‐bed. Since mobilization is important in prolonged ICU courses typical for ECMO patients, this might be an important benefit. Other benefits of DLC were the longer runtime of the initial cannula set and fewer suction events.
Creating organizational value and sustainability through green HR practices: An innovative approach with the moderating role of top management support
Authors: Chatterjee Sheshadri , Chaudhuri Ranjan , Vrontis Demetris
Published: June 2023

Green human resource management (GHRM) seeks to reorient human resource strategy and practices to an organization's environmental sustainability goals. A small body of research has so far shown that GHRM is positively related to organizational sustainability, yet the results are somewhat variable. This calls into question regarding the boundary conditions of this relationship. In this study, the moderating role of top management team (TMT) support has been examined as senior managers have a key role to play in ensuring that GHRM is valued, widely recognized, and implemented as intended. Based on the existing literature, a model has been developed and then tested with partial least square structural equation modeling, with feedback from 372 human resource managers across several organizations. The results show a positive relationship between GHRM and sustainability, and the results also show that the TMT support strengthens this relationship. Importantly, the study reveals a positive and significant relationship between sustainability and organizational performance.
Sample Size and Power Determination for Multiparameter Evaluation in Nonlinear Regression Models with Potential Stratification
Authors: Martens Michael J. , Kim Soyoung , Ahn Kwang Woo
Published: June 2023

Sample size and power determination are crucial design considerations for biomedical studies intending to formally test the effects of key variables on an outcome. Other known prognostic factors may exist, necessitating the use of techniques for covariate adjustment when conducting this evaluation. Moreover, the main interest often includes assessing the impact of more than one variable on an outcome, such as multiple treatments or risk factors. Regression models are frequently employed for these purposes, formalizing this assessment as a test of multiple regression parameters. But, the presence of multiple variables of primary interest and correlation between covariates can complicate sample size/power calculation. Given the paucity of available sample size formulas for this context, these calculations are often performed via simulation, which can be both time-consuming as well as demanding extensive probability modeling. We propose a simpler, general approach to sample size and power determination that may be applied when testing multiple parameters in commonly used regression models, including generalized linear models as well as ordinary and stratified versions of the Cox and Fine–Gray models. Through both rigorous simulations and theoretical derivations, we demonstrate the formulas' accuracy in producing sample sizes that will meet the type I error rate and power specifications of the study design.
‘Burger, Chips and a Side Order of Depression to Go Please’
Authors: Marsh Geraldine
Published: June 2023

The intention of this paper is to explore how societal food choices may be affecting our clients’ mentation and to discuss alternative drivers behind their feelings of anger, sadness and fear that potentially lead to fixed moods of anxiety and depression. The current perception of nutrition within psychotherapy is framed within lifestyle, self‐care enquiry and a rich, metaphorical use of digestive systems within the therapeutic process. Yet over the last two decades the synthesis of nutritional therapy with psychiatry has theorized a network of ideas under the umbrella title of ‘nutritional psychiatry’, which links positivist research to suggest poor diet and gut microbiome health are also factors behind the development of mental illnesses. The differing epistemological positions in these two fields create a challenge to the case study used which explores working psychotherapeutically with a client's food choices, whilst interrogating whether nutritional psychiatric‐derived theories relate to the client work and how to incorporate these ideas within psychotherapeutic practice.
The architectonic of Foucault's critique
Authors: Lorenzini Daniele , Tiisala Tuomo
Published: June 2023

This paper presents a new interpretation of Michel Foucault's critical project. It is well known that Foucault's genealogical critique does not focus on issues of justification, but instead tackles “aspectival captivity,” that is, apparently inevitable limits of thought that constrain the subject's freedom but that, in fact, can be transformed. However, it has not been recognized that, according to Foucault, critique can proceed along two distinct paths. In a key passage of “What Is Critique?,” Foucault states that critique is tasked with questioning truth about its effects of power and with questioning power about its discourses of truth. We show that this “double movement” organizes Foucault's critical project as a whole, giving it a significantly wider scope and a more complex structure than has been previously acknowledged. At the heart of the above‐mentioned bifurcation lies an apparent tension between two contrastive roles Foucault assigns to truth‐telling in the context of critique: on the one hand, truth‐telling (as avowal) is a target of critique; on the other, truth‐telling (as parrhesia) is one of critique's methods. We argue that combining these two dimensions in a unified account is crucial for understanding and re‐evaluating Foucault's critical project as a whole. By showing that truth‐telling remains an essential element of Foucauldian critique, this paper also rectifies some influential misinterpretations according to which Foucault's critical project seeks to eliminate truth from the picture.
Food fraud detection using explainable artificial intelligence
Authors: Buyuktepe Okan , Catal Cagatay , Kar Gorkem , Bouzembrak Yamine , Marvin Hans , Gavai Anand
Published: June 2023

Recently, the global food supply chain has become increasingly complex, and its scalability has grown. From farm to fork, the performance of food‐producing systems is influenced by significant changes in the environment, population and economy. These changes may cause an increase in food fraud and safety hazards and hence, harm human health. Adopting artificial intelligence (AI) technology in the food supply chain is one strategy to reduce these hazards. Although the use of AI has been rising in numerous industries, such as precision nutrition, self‐driving cars, precision agriculture, precision medicine and food safety, much of what AI systems do is a black box due to its poor explainability. This study covers numerous use cases of food fraud risk prediction using explainable artificial intelligence (XAI) techniques, such as LIME, SHAP and WIT. We aimed to interpret the predictions of a machine learning model with the aid of these technologies. The case study was performed on a food fraud dataset using adulteration/fraud notifications retrieved from the Rapid Alert System for Food and Feed system and economically motivated adulteration database. A deep learning model was built based on this dataset and XAI tools have been investigated on the proposed deep learning model. Both features and shortcomings of the current XAI tools in the food fraud area have been presented.
Visual hypersensitivity in patients treated with anti‐calcitonin gene–related peptide (receptor) monoclonal antibodies
Authors: de Vries Lentsch Simone , Perenboom Matthijs J. L. , Carpay Johannes A. , MaassenVanDenBrink Antoinette , Terwindt Gisela M.
Published: June 2023

Objective

To evaluate the effect of treatment with anti‐calcitonin gene–related peptide (CGRP; receptor) antibodies on visual hypersensitivity in patients with migraine.

Background

Increased visual sensitivity can be present both during and outside migraine attacks. CGRP has been demonstrated to play a key role in light‐aversive behavior.

Methods

In this prospective follow‐up study, patients treated for migraine with erenumab (n = 105) or fremanezumab (n = 100) in the Leiden Headache Center were invited to complete a questionnaire on visual sensitivity (the Leiden Visual Sensitivity Scale [L‐VISS]), pertaining to both their ictal and interictal state, before starting treatment (T0) and 3 months after treatment initiation (T1). Using a daily e‐diary, treatment effectiveness was assessed in weeks 9–12 compared to a 4‐week pre‐treatment baseline period. L‐VISS scores were compared between T0 and T1. Subsequently, the association between the reduction in L‐VISS scores and the reduction in monthly migraine days (MMD) was investigated.

Results

At 3 months, the visual hypersensitivity decreased, with a decrease in mean ± standard deviation (SD) ictal L‐VISS (from 20.1 ± 7.7 to 19.2 ± 8.1, p = 0.042) and a decrease in mean ± SD interictal L‐VISS (from 11.8 ± 6.6 to 11.1 ± 7.0, p = 0.050). We found a positive association between the reduction in MMD and the decrease in interictal L‐VISS (β = 0.2, p = 0.010) and the reduction in ictal L‐VISS (β = 0.3, p = 0.001).

Conclusion

A decrease in visual hypersensitivity in patients with migraine after treatment with anti‐CGRP (receptor) antibodies is positively associated with clinical response on migraine.
Domesticated Australian wattle seeds (Acacia species): nutritional values, techno‐functional properties and toxicological assessments after roasting
Authors: Adiamo Oladipupo Q. , Phan Anh Dao Thi , Akter Saleha , Sivakumar Dharini , Seke Faith , Cunningham Peter , Sultanbawa Yasmina
Published: June 2023

This study evaluated the nutritional composition, anti‐nutritional factors, djenkolic acid (DKA) contents and techno‐functional properties of commercial raw, light and medium roasted wattle seed (WS) flour from 10 domesticated Australian Acacia species. The results showed that the species are a good source of dietary fibre, protein, fat and minerals (K, Ca, Mg, P and Fe). Moreover, the species have substantial amounts of linolenic acid and essential amino acids (EAAs), except for methionine and phenylalanine, indicating the high fat and protein quality of the species. Low‐trypsin inhibitor activity (TIA) and DKA contents were found in the species, except for the high TIA in A. longifolia spp. sophorae (18.3 mg TUI/g), A. longifolia spp. longifolia (12.3 mg TUI/g) and A. provincialis (12.2 mg TUI/g). In contrast, light and medium roasting effectively reduced the TIA and DKA levels as well as foaming and emulsifying properties. The greatest reduction in these properties was noticed in medium‐roasted samples. However, roasting appears to retain most of the nutritive value in the species and, the species exhibited high‐water absorption capacity, making them suitable for use as ingredients in bakery applications.
Effects of different preservation schemes on isolated rat artery
Authors: Ren Zhang‐Yong , Wu Qiao , Pan Bing , Liu Jia‐Zong , He Qiang , Lang Ren , Lyu Shao‐Cheng
Published: June 2023

Allogeneic blood vessels are regarded as one of the best natural substitutes for diseased blood vessels due to their good vascular compliance and histocompatibility. Since the supply and demand of allograft blood vessels do not always match in time and space, a good preservation scheme for isolated blood vessels is essential. The abdominal aortas of 110 male Sprague–Dawley (SD) rats were randomly divided into three groups, including cold storage group (4°C) (CSG), frozen storage group (FSG) and ambient storage group (25 ± 2°C) (ASG). Seven time points of preservation for 1, 3, 5, 7, 14, 30 and 90 days were set for detection. The changes in vascular physiological function were evaluated by MTT test and vasoconstriction ability detection, and the changes in vascular wall structure were evaluated by the tension tolerance test and pathological staining. The vascular function of CSG was better than FSG within first the 7 days, but the result was opposite since the 14th day. The vascular wall structure, collagen and elastic fibres of vessels, in CSG, showed oedema within 30 days, and continuous disintegration and rupture at 90 days. The vessel wall structure of FSG remained intact within 90 days. The tensile strength of the vessels in CSG was better than that in FSG within 5 days, and there was no statistical difference between the two groups between the 7th and 30th day, and then, the FSG was higher than CSG on the 90th day. Both cold storage and frozen storage could be applied as safe and effective preservation schemes for isolated rat artery within first 30 days. Cold storage is recommended when the storage time is <14 days, and then, frozen storage is better.
Price promotions as a threat to brands
Authors: Inderst Roman , Obradovits Martin
Published: June 2023

Manufacturers frequently resist heavy discounting of their products by retailers. Since low prices should increase demand and manufacturers could simply refuse to fund deep price promotions, such resistance is puzzling at first sight. We develop a model in which price promotions cause shoppers to evaluate the relative importance of quality and price against a market‐wide reference point. With deep discounting, consumers perceive quality differences as less pronounced, eroding brand value and the bargaining position of brand manufacturers. This reduces their profits and may even lead to a delisting of their products. By linking price promotions to increased one‐stop shopping and more intense retail competition, our theory also offers an explanation for the rise of store brands.
The experience of pain and its ontological modelling from a philosophical point of view: Phenomenological description and ontological revision of the McGill Pain Questionnaire
Authors: Lanfredini Roberta , Cipriani Letizia
Published: June 2023

The aim of the article is to identify, on the basis of the phenomenological and ontological analysis of the experience of pain and the ways in which this experience is expressed in natural language, an ontological modelling of the language of pain and, at the same time, a revision of the traditional version of the McGill questionnaire. The purpose is to provide a different characterisation and an adequate evaluation of the phenomenon of pain, and, consequently, an effective measure of the actual experience of the suffering subject.
Major histocompatibility complex class IIα and IIβ of pufferfish (Takifugu obscurus): Identification and functional characterization in response to bacterial challenge
Authors: Qian Kun , Fu Shengli , Wang Junru , Li Yuan , Xian Jianan , Ye Jianmin
Published: June 2023

Classical major histocompatibility complex (MHC) class II molecules play an essential role in immune system. In this study, MHC IIα (Pf‐MHC IIα) and MHC IIβ (Pf‐MHC IIβ) homology genes from pufferfish (Takifugu obscurus) were cloned and their functional characterization in response to bacterial challenge was identified. The nucleotide sequences of the open reading frames (ORFs) of pufferfish Pf‐MHC IIα and Pf‐MHC IIβ were 708 bp and 750 bp, encoding 235 aa and 249 aa, respectively. The structure of Pf‐MHC IIα or Pf‐MHC IIβ contained a signal peptide, an α1/β1 domain, an α2/β2 domain, a transmembrane region and a cytoplasmic region. Multiple sequence alignment and phylogenetic analysis showed that Pf‐MHC IIα and Pf‐MHC IIβ molecules had the highest similarity with Fugu rubripes (Takifugu rubripes). Cellular localization analysis indicated that the distribution of Pf‐MHC IIα and Pf‐MHC IIβ was in the lymphocyte membrane and cytoplasm. qRT‐PCR results showed that Pf‐MHC IIα and Pf‐MHC IIβ expressed relatively high in skin, gills and gut. In addition, after stimulation challenge in vitro (lipopolysaccharide, or polyinosinic: polycytidylic acid) and in vivo (A. hydrophila), the mRNA expressions of Pf‐MHC IIα and Pf‐MHC IIβ were significantly up‐regulated in lymphocytes and in tissues of skin, gills, gut and head kidney. Moreover, Pf‐MHC IIα or Pf‐MHC IIβ neutralization reduced the ability of A. hydrophila to induce the expressions of lymphocyte cytokines (TNF‐α, IL‐1β and IL‐10). Overall, it is speculated that Pf‐MHC IIα and Pf‐MHC IIβ may play an important role in the host response against A. hydrophila in pufferfish.
Development and evaluation of an intelligentUVCsterilization system for raw aquatic food production
Authors: Li You , Liu Feng , Xing Shaohua , Wang Xiang , Liu Xingxing
Published: June 2023

Raw aquatic food is regarded as an important source of proteins. However, the presence of various bacteria can increase the risk of disease in humans. As a result, a crucial step in the processing of aquatic products is the disinfection of raw aquatic food. An intelligent ultraviolet c radiation (UVC) sterilization system was established and evaluated in this study. On the automated production line, the UVC lamp's sterilization intensity can be automatically adjusted to achieve intelligent sterilization of the various aquatic product categories. The system was implemented and evaluated for oyster surface sterilization experiments in the production line. The quality indicators of oysters, such as volatile salt nitrogen content and aerobic bacterial count, were measured before and after sterilization. The average sterilization rate of the intelligent system is 96.4%. The results showed that the system had an excellent sterilization effect and improved the shelf life of aquatic products.
Identifying Medicare beneficiaries with Alzheimer's disease and related dementia using home healthOASISassessments
Authors: Bélanger Emmanuelle , Rosendaal Nicole , Gutman Roee , Lake Derek , Santostefano Christopher M. , Meyers David J. , Gozalo Pedro L.
Published: June 2023

Background

Home health services are an important site of care following hospitalization among Medicare beneficiaries, providing health assessments that can be leveraged to detect diagnoses that are not available in other data sources. In this work, we aimed to develop a parsimonious and accurate algorithm using home health outcome and assessment information set (OASIS) measures to identify Medicare beneficiaries with a diagnosis of Alzheimer's disease and related dementia (ADRD).

Methods

We conducted a retrospective cohort study of Medicare beneficiaries with a complete OASIS start of care assessment in 2014, 2016, 2018, or 2019 to determine how well the items from various versions could identify those with an ADRD diagnosis by the assessment date. The prediction model was developed iteratively, comparing the performance of different models in terms of sensitivity, specificity, and accuracy of prediction, from a multivariable logistic regression model using clinically relevant variables, to regression models with all available variables and predictive modeling techniques, to estimate the best performing parsimonious model.

Results

The most important predictors of having a diagnosis of ADRD by the start of care OASIS assessment were a prior discharge diagnosis of ADRD among those admitted from an inpatient setting, and frequently exhibiting symptoms of confusion. Results from the parsimonious model were consistent across the four annual cohorts and OASIS versions with high specificity (above 96%), but poor sensitivity (below 58%). The positive predictive value was high, over 87% across study years.

Conclusions

The proposed algorithm has high accuracy, requires a single OASIS assessment, is easy to implement without sophisticated statistical models, and can be used across four OASIS versions and in situations where claims are not available to identify individuals with a diagnosis of ADRD, including the growing population of Medicare Advantage beneficiaries.
Circadian rhythm alterations affecting the pathology of neurodegenerative diseases
Authors: Canever Jaquelini Betta , Queiroz Letícia Yoshitome , Soares Ericks Sousa , de Avelar Núbia Carelli Pereira , Cimarosti Helena Iturvides
Published: June 2023

The circadian rhythm is a nearly 24‐h oscillation found in various physiological processes in the human brain and body that is regulated by environmental and genetic factors. It is responsible for maintaining body homeostasis and it is critical for essential functions, such as metabolic regulation and memory consolidation. Dysregulation in the circadian rhythm can negatively impact human health, resulting in cardiovascular and metabolic diseases, psychiatric disorders, and premature death. Emerging evidence points to a relationship between the dysregulation circadian rhythm and neurodegenerative diseases, suggesting that the alterations in circadian function might play crucial roles in the pathogenesis and progression of neurodegenerative diseases. Better understanding this association is of paramount importance to expand the knowledge on the pathophysiology of neurodegenerative diseases, as well as, to provide potential targets for the development of new interventions based on the dysregulation of circadian rhythm. Here we review the latest findings on dysregulation of circadian rhythm alterations in Parkinson's disease, Alzheimer's disease, Huntington's disease, amyotrophic lateral sclerosis, multiple sclerosis, spinocerebellar ataxia and multiple‐system atrophy, focusing on research published in the last 3 years.

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Does BRAF V600E mutation affect recurrence rate of ameloblastomas? Systematic review and meta‐analysis
Authors: Martins‐de‐Barros Allan Vinícius , Silva Caio César Gonçalves , Gonçalves Kalyne Kelly Negromonte , de Albuquerque Cavalcanti Almeida Renata , de Oliveira e Silva Emanuel Dias , da Costa Araújo Fábio Andrey , Robinson Liam , van Heerden Willie F. P. , de Vasconcelos Carvalho Marianne
Published: June 2023

Objective

The objective of this systematic review with meta‐analysis was to critically evaluate the available data on the association of the BRAF V600E mutation and recurrence rate of ameloblastomas.

Materials and Methods

This systematic review was registered in Prospero (CRD42020183645) and performed based on the PRISMA statement. A comprehensive search in PubMed, Web of Science, Scopus and Cochrane Library databases was performed in order to answer the question “Does BRAF V600E mutation affect recurrence rate of ameloblastomas?” Methodological quality and risk of bias of the selected studies were assessed with JBI Critical Appraise Tool. Meta‐analysis of quantitative data was conducted with RevMan 5.3 and Jamovi 2.3.

Results

The initial search identified 302 articles, and 21 met the inclusion criteria. A total of 855 subjects with ameloblastoma were included in the analysis. The pooled measures for frequency of BRAF V600E mutation was 65.30% (95% CI: 0.56–0.75; p < .001; I2 = 90.85%; τ = 0.205; p < .001), and the pooled recurrence rate was 25.30% (95% CI: 0.19–0.31; p < .001; I2 = 79.44%; τ = 0.118; p < .001). No differences in recurrence rate were observed between the BRAF V600E and wild type BRAF ameloblastomas, with a pooled Odds Ratio of 0.93 (95% CI: 0.56–1.54; p = .78; I2 = 31%; p = .09).

Conclusions

BRAF V600E mutation is a frequent event in ameloblastomas, but does not increase nor reduce its recurrence rate, and thus have a limited value in predicting its prognosis.
Associations of Household Food Insecurity With Academic Outcomes in Early Adolescents
Authors: Orihuela Catheryn A. , Cox Callista , Evans Retta , Mrug Sylvie
Published: June 2023

BACKGROUND

Food insecurity is characterized by limited access to adequate food due to a lack of money or resources (eg, lack of transportation to obtain food). School aged children who are experiencing food insecurity are at greater risk for poor academic outcomes, but previous studies have not examined the effects of food insecurity on specific academic outcomes over time.

METHOD

This study examined food insecurity as a risk factor for subsequent academic skills, enablers, and achievement. As part of a larger longitudinal study, middle school students (N = 112; meanage = 12.14, SD = 0.41; 50% female; 68% black/African American, 14% white, 13% Hispanic or Latino, 5% other) reported on food insecurity at baseline, while teachers reported on students' academic skills and enablers at both baseline and 12 months later at 1 year follow up. Math and English/Language Arts grades were obtained from the schools at each wave.

FINDINGS

Food insecurity predicted lower academic skills over time but was unrelated to academic enablers and grades.

IMPLICATIONS

Considering a whole school, whole community, whole child (WSCC) framework, this study will also discuss the important role schools and communities have in reducing food insecurity in middle school students.

CONCLUSIONS

These results support negative long‐term effects of food insecurity on academic skills in early adolescents.
The phonology of Atchan
Authors: Russell Katherine R.
Published: June 2023

Atchan is a Kwa language spoken by approximately 150,000 people in and around Abidjan in southern Côte d’Ivoire. In this paper, I describe aspects of the phonology of Atchan, including its consonant and vowel inventory, syllable structure, patterns of nasalisation, and lexical and grammatical tone. I provide examples from primary data collected in collaboration with native speakers of Atchan. This article offers the first comprehensive sketch of Atchan phonology in the literature.
Acceptance and commitment therapy for psychosis: Current status, lingering questions and future directions
Authors: Morris Eric M. J. , Johns Louise C. , Gaudiano Brandon A.
Published: June 2023

Purpose

Acceptance and Commitment Therapy for psychosis (ACTp) is a contextual behavioural intervention that promotes psychological flexibility by fostering active acceptance, cognitive defusion, values construction and committed action to enhance well‐being and recovery. Multiple studies have shown that ACTp is acceptable and efficacious, but questions remain as to its distinction from similar approaches and the conditions under which it would be implemented most effectively.

Methods

We present the current evidence for processes and outcomes of ACTp and summarise the qualitative findings of experiences of service users in ACT programmes. We compare ACTp with other cognitive behavioural therapies and mindfulness‐informed interventions for psychosis.

Results

Acceptance and commitment therapy for psychosis is promising as a pragmatic, process‐driven intervention model. Further efforts are needed to investigate psychological flexibility in the context of psychosis with observational, experimental and intervention studies that will inform model scope and treatment refinement. Additionally, implementation research is the necessary next step, including how support persons can be trained in ACTp. Lower intensity and technology‐assisted approaches have the potential to reduce barriers to accessing ACTp and extend impact.

Conclusions

Over the last 20 years, ACTp has demonstrated meaningful effects in individual and group formats in a range of settings, targeting outcomes such as rehospitalisation, depression, psychotic symptom distress and impact. Future work should focus on how best to integrate ACTp with other current evidence‐based interventions for psychosis.
A national survey of doctoral psychology education and training in suicide risk and violence risk assessment and management
Authors: Kleespies Phillip M. , Feinman Anna , AhnAllen Christopher G. , Hausman Catherine , Thach Tina , Woodruff Jason , Loomis Samuel , Bongar Bruce
Published: June 2023

Introduction

When, in the judgment of a mental health professional, patient suicide risk and/or patient violence risk are considered imminent, they have been referred to as behavioral emergencies. Past surveys have suggested that education and training with these emergency situations have been inadequate. The present study was undertaken to obtain more current information on the training that psychologists receive in these areas of practice.

Method

All directors of APA‐accredited graduate psychology programs and all directors of APA‐accredited predoctoral psychology internship programs were asked to complete an online survey inquiring about such training provided in their programs.

Results

Results indicated that both sets of directors rated such doctoral training in suicide risk assessment and management as very important. Internship directors, however, were significantly more likely than graduate program directors to state that psychologists should be required to complete continuing education courses on other‐directed violence risk. Serious gaps in training were identified; that is, only 59.2% of psychology graduate directors reported that their program offered training in safety planning for suicide risk and only 25.4% reported that their program offered training in safety planning for violence risk.

Conclusion

Given that serious injury and even death can occur from patient suicidal behavior and/or a patient violent behavior, the implications of these findings are discussed.
A multi‐centre prospective evaluation of internet research habits among owners seeing a veterinary oncologist
Authors: Hauss Jennifer , Miller Mairin E. , Tansey Colleen , Szlosek Donald , Murphy Lisa A. , Nakamura Reid K.
Published: June 2023

The purpose of this study is to evaluate the internet‐use among pet owners seeing a veterinary oncologist. Over a two‐month period, 137 questionnaires were collected at three specialty hospitals around a large urban city. Approximately 85% of respondents reported using the internet to research their pet's condition and/or treatment. A search engine was the most employed means however veterinary university websites were considered to provide the most accurate information. The odds of owners who researched their own health condition online researching their pet's condition was 4.3 (95% CI: 1.2–23.1,p < .021) times as high as owners who did not research their own health condition. The odds of owners who have been to their oncologist previously to research their pet's condition was 4.7 (95% CI: 26.9.3,p < .001) times as high than owners who have not been to an oncologist previously. Oncologists should be aware internet use among pet owners appears common and further research to assess the accuracy and readability of veterinary medical websites appears indicated.
DESIGNING TECHNO-ECONOMIC OFF-GRID PHOTOVOLTAIC SYSTEM USING AN IMPROVED DIFFERENTIAL EVOLUTION ALGORITHM
Authors: Rockson Seth Bedu , Md Rasid Madihah , Anuar Mohd Shafiq , Hussin Siti Maherah , Rosmin Norzanah , Nordin Norjulia Mohamad , Gyan Michael
Published: June 2023

Conventional power generation is one of the main contributors to the phenomenon of the greenhouse effect. This has led to a diversification of electricity sources including environmentally friendly energy sources such as solar energy. Off-grid PV systems have gained some traction due to their cost-effectiveness for rural communities. However, the intermittent nature of solar is the main challenge to developing the off-grid PV system. Moreover, the high capital cost of PV systems as well as the storage batteries becomes the main concern for all PV users. Thus, this study aims to optimize the size of the PV system and battery simultaneously and design a cost-effective off-grid photovoltaic system considering various aspects such as battery power, solar irradiance, and PV panel selection while ensuring system reliability. The proposed system was optimized using improved Differential Evolution (DE) and its effectiveness was tested by comparing the results with Particle Swarm Optimization (PSO) and Genetic Algorithm (GA). The Improved DE algorithm provides the highest average cost savings compared to other algorithms, which is $500 per year. It is recommended that this method is very useful in the optimization of off-grid PV systems, considering other uncertainties that affect PV system performance.
THE EFFECT OF THERMAL TREATMENT ON ANTIOXIDANT AND PHYSICOCHEMICAL PROPERTIES OF BLACK SHALLOT (ALLIUM ASCALONICUM)
Authors: Tran Gia-Buu , Ngo Thanh-Minh Thi
Published: June 2023

Black shallot is the newly developed food product from shallot (Allium ascalonicum), which is characterized by dark brown color, sweet taste and jelly texture. However, the effect of thermal treatment on physicochemical properties, bioactive compounds, antioxidant activity has not been assessed yet. In this study, we determined the changes of some physicochemical properties (reducing sugar, pH, moisture, and acidity), polyphenols, and its antioxidant activity (via DPPH radical scavenging assay) during aging process at three different temperatures (60, 70, 80oC) with sampling intervals 3 days for a 21-day period. All thermal treatment conditions gradually reduced the moisture and pH versus increased the acidity, reducing sugar, total polyphenol content, and antioxidant activity. The optimal conditions to produce the antioxidant and polyphenols - enriched black shallot were 70oC for 18 days (63.95 ± 1.24 % and 52.86 ± 2.02 mg of GAE/g DW, respectively). These findings not only gives the basis for the optimization of processing for improvement food quality with desired attributes but also suggests black shallot as the promising source to extract bioactive compounds for application in pharmaceutical and food industry.
NUMERICAL STUDY ON EFFECT OF PHASE ANGLE ON TORSIONAL AND LATERAL VIBRATIONS IN POWER TRANSMISSION SYSTEM EMPLOYING CARDAN SHAFT
Authors: Omar Mohd Hazri , Ab Rahim Muhajir , Md Rejab Mohd Noor Arib
Published: June 2023

A power transmission system driven by a Cardan shaft may experience severe vibration due to fluctuating rotational speed and moments transferred to the final drives, determined by the level of angular misalignment and phasing of the joint yokes. This study investigates the potential of an out-of-phase position displaced by a phase angle in attenuating vibrations. The governing equations representing the dynamics of the system are derived. The torsional and lateral vibration responses are numerically calculated over a range of input rotational speeds. When attenuating the vibration, the phase angle is set equal to the maximum twist that occurs during the in-phase position. Relative attenuation is used to investigate the phase angle effects. The effectiveness is studied for different levels of static angular misalignment. For the considered system, the results showed that for static angular misalignment greater than 20 degrees, the proposed phase angle arrangement could attenuate torsional vibration by more than 10 percent and significantly attenuate the lateral vibration.
STUDY THE INFLUENCE OF WELDING PARAMETERS BY TAGUCHI’S DESIGN ON THE MECHANICAL PROPERTIES OF WELDED MILD STEEL (S235JR)
Authors: Saleh Elfallah Saleh Suliman
Published: June 2023

Gas metal arc welding is a leading process in fusion welding with increased productivity and good quality. The welding parameters are crucial in determining welding quality, cost, and productivity. In this study, mild steel with a 10-mm-thick sheet was welded by gas metal arc welding under predetermined parameters of welding voltage, wire feed speed, and groove shape. The analysis made by Taguchi’s design to investigate the effect of these parameters on tensile strength and Vickers micro-hardness of welding. The microstructure of the fusion zone and heat-affected zone is analyzed to monitor their change concerning the mechanical properties. The results showed that tensile strength decreased with decreased hardness. Also, the tensile strength and hardness were higher (a maximum of 305 MPa and 2170 HVN) at welding made at a lower voltage (20 volts), lower wire feed speed (5.9 m/min), and V-shaped base metal groove. The increased precipitation of perlite structure was shown during welding, which has lower tensile strength and hardness. Widmanstatten ferrite and coarser α-ferrite were presented for welding with a lower cooling time. Taguchi’s design showed that voltage at 20 volts has the highest effect on tensile strength, followed by wire feed speed at 5.9 m/min and V-shaped welding.
The functional Orlicz–Brunn–Minkowski inequality for q‐torsional rigidity
Authors: Hu Jinrong , Zhang Ping
Published: June 2023

In this paper, we obtain the functional Orlicz–Brunn–Minkowski inequality and the functional Orlicz–Minkowski inequality for q‐torsional rigidity in the smooth category. Furthermore, using an approximation method, we give the general functional Orlicz–Brunn–Minkowski inequality for q‐torsional rigidity. As a corollary, we reveal that the functional Orlicz–Brunn–Minkowski inequality is equivalent to the functional Orlicz–Minkowski inequality for q‐torsional rigidity in the smooth category. We also give some applications with respect to these two inequalities.
Computational Framework Development for Heat Transfer Studies in Liquid Metal-Cooled Small-Scale Heat Sinks With Non-Circular Cross Sections
Authors: Pourghasemi Mahyar , Fathi Nima
Published: June 2023

The present work provides a reliable computational framework to investigate the laminar and turbulent forced convection of sodium and sodium–potassium (Na, NaK) in small-scale heat sinks with hydraulic diameters between 1 mm and 5 mm. Na and NaK flow and heat transfer are studied numerically for a wide range of Reynolds numbers from 600 to 9000 in three sharp-cornered miniature heat sinks with rectangular, pentagonal, and hexagonal cross sections. For a fixed surface area to volume ratio, it is observed that the rectangular minichannel heat sink provides the highest convective heat transfer rates. The rectangular miniature heat sink is shown to provide 280% higher convective heat transfer rates in comparison with the pentagonal heat sink. Moreover, the obtained convective heat transfer coefficients for NaK are almost 20% higher than the ones for Na in the investigated pentagonal heat sink. For the same flow Peclet number in the rectangular and hexagonal heat sinks, both Na and NaK provide nearly identical average Nusselt numbers. However, NaK shows greater local and average Nusselt numbers compared to Na at the same Reynolds number.
Entropy Generation Analysis on a Metal Foam in an Automotive Exhaust Line With Thermoelectric Generator
Authors: Buonomo Bernardo , di Pasqua Anna , Manca Oronzio , Nappo Sergio
Published: June 2023

This paper presents a numerical solution for the entropy generation analysis of a two-dimensional steady-state convective regime in an aluminum foam. The analysis specifically focuses on a parallel plate channel filled partially or totally with metal foam, which incorporates on the external surface a thermoelectric generator (TEG). Local thermal equilibrium hypothesis is considered in the investigation to model the behavior of the metal foam and heat transfer within the channel. An exhaust gas is considered a working fluid, and its thermophysical properties are the same as those of air. The independence of the properties from temperature is considered. An internal energy production is assumed inside the TEG. The governing equations related to the physical problem with metal foam, exhaust gas, and TEG are solved by ansys fluent code. The investigation is accomplished for different aluminum foam thicknesses with various mass flowrate of working fluid. In the analysis, different values of pore density and porosity are assigned to the aluminum foam. The first is with 5, 10, 20, and 40 PPI, the second is from 0.90 to 0.978. Entropy generation due to friction and thermal effects as well as total entropy generation are reported. For all pore density and porosity values, the total entropy generation presents an increase related to an increment in mass flowrate. Bejan number decreases with increment in dimensionless thickness and mass flowrate. It increases when the porosity value increases whereas at high mass flowrate and for assigned porosity the values present small difference for different pore density values.
The role of lung ultrasonography in the SARS-CoV-2 vaccines and variants era: a case report
Authors: Cepeda Javier González , Esteves Ana Luisa , Marín-Baselga Raquel , Tung-Chen Yale
Published: June 2023

.
“Reverse” curtain sign for diagnosis of pneumothorax
Authors: Huang Chun-Ta , Ruan Sheng-Yuan
Published: June 2023

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Semimembranosus muscle tear masquerading as a hypervascular tumor: ultrasonographic differential diagnosis for gluteal pain syndrome
Authors: Wu Wei-Ting , Mezian Kamal , Ricci Vincenzo , Chang Ke-Vin , Ozcakar Levent
Published: June 2023

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Characterization of Two Novel Inhibitors of the Mycobacterium tuberculosis Cytochrome
bc
1
Complex
Authors: Gries Raphael , Dal Molin Michael , Chhen Jason , van Gumpel Edeltraud , Dreyer Viola , Niemann Stefan , Rybniker Jan
Published: June 2023

Drug-resistant tuberculosis is a global health care threat calling for novel effective treatment options. Here, we report on two novel cytochrome
bc
1
inhibitors (MJ-22 and B6) targeting the
Mycobacterium tuberculosis
respiratory chain with excellent intracellular activities in human macrophages. Both hit compounds revealed very low mutation frequencies and distinct cross-resistance patterns with other advanced cytochrome
bc
1
inhibitors.
KIF16B Mediates Anterograde Transport and Modulates Lysosomal Degradation of the HIV-1 Envelope Glycoprotein
Authors: Weaver Nicholas , Hammonds Jason , Ding Lingmei , Lerner Grigoriy , Dienger-Stambaugh Krista , Spearman Paul
Published: June 2023

The HIV-1 envelope glycoprotein is an essential component of HIV-1 particles. The cellular pathways that contribute to incorporation of envelope into particles are not fully understood.
Whole-Genome Sequence of Pseudomonas frederiksbergensis Strain A6, Isolated from the Rhizosphere of Pepper (Capsicum annuum L.)
Authors: Bashizi Tino , Kim Min-Ji , Lee GyuDae , Tagele Setu Bazie , Shin Jae-Ho
Published: June 2023

This research presents the whole-genome sequence of
Pseudomonas frederiksbergensis
strain A6, which was isolated from the rhizosphere soil of pepper (
Capsicum annuum
L.). The genome of the strain is composed of a single chromosome with 6,711,706 bp, and the GC content is 58.7%.
Phosphoproteome Profiling of Klebsiella pneumoniae under Zinc-Limited and Zinc-Replete Conditions
Authors: Reitzel Chelsea , Sukumaran Arjun , Zanetti Christina , Muselius Benjamin , Geddes-McAlister Jennifer
Published: June 2023

The bacterial pathogen
Klebsiella pneumoniae
causes nosocomial infections with the acquisition of multidrug resistance, impeding treatment options. This study investigated the effect of zinc limitation on the phosphoproteome of
K. pneumoniae
using quantitative mass spectrometry. New insight is provided into cellular signaling methods used by the pathogen to respond to nutrient-limited environments.
Diversity and Standard Nomenclature of Staphylococcus aureus Hyaluronate Lyases HysA and HysB
Authors: Hisatsune Junzo , Koizumi Yuma , Tanimoto Kotaro , Sugai Motoyuki
Published: June 2023

Numerous whole-genome sequence data for
Staphylococcus aureus
harboring two hyaluronate lyase (Hys) genes have been registered. However, the assigned gene names for
hysA1
and
hysA2
are incorrect in some assembled data, and in some cases, the genes are annotated differently as
hysA
and
hysB
.
Comparing Ahmed-FP7 to Baerveldt-250 and Baerveldt-350 surgical outcomes: 1-year results from a retrospective cohort study leveraging the electronic health record
Authors: Shen Leo L , Guo Xinxing , Johnson Thomas V , Friedman David , Boland Michael V , McGlumphy Elyse J
Published: June 2023

Objective

To compare outcomes following Ahmed-FP7 (AGI-FP7), Baerveldt-250mm2(BGI-250), or Baerveldt-350mm2(BGI-350) implantation.

Methods and analysis

Retrospective cohort study comprising 800 eyes from 800 individuals who underwent surgery 1 January 2016–31 December 2020 at a tertiary-care institution. Data were extracted from standardised fields in the electronic health record. Primary outcome was failure (defined as intraocular pressure (IOP) ≤5 mm Hg or >18 mm Hg or reduction <20% at two consecutive visits from month 3 onwards; or visual acuity (VA) loss ≥3 lines; or return to the operating room (OR)). Secondary outcomes were IOP, VA, number of follow-up visits and return to the OR.

Results

A total of 523 AGI-FP7, 133 BGI-250 and 144 BGI-350 cases were analysed. The AGI-FP7 group was more likely to be younger and diagnosed with secondary glaucoma, with a higher mean baseline IOP (28.5±12.2 vs 22.0±7.7 mm Hg in BGI-250 and 23.4±9.0 in BGI-350, p<0.001). Cumulative failure rate at month 12 was 30% (AGI-FP7) vs 39% (BGI-250) vs 33% (BGI-350, p=0.159). Mean IOP at month 12 was lower in the BGI-350 group compared with AGI-FP7 (12.4±4.4 vs 14.8±5.6 mm Hg, p=0.003) but not BGI-250 (vs 13.1±4.6, p=0.710). Target IOP was achieved in 71% of AGI-FP7, 66% BGI-250, and 76% BGI-350. VA loss and rates of return to the OR did not differ between groups. Both BGI-250 and BGI-350 had more follow-up visits than AGI-FP7 (p<0.001).

Conclusion

These three glaucoma drainage devices performed similarly within 1 year, with no difference in failure rates despite differing baseline patient characteristics.