bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of Oxide Thickness on Technical Aluminium Alloys—A Comparison of Characterization Methods
Authors: Gruber Ralph , Singewald Tanja Denise , Bruckner Thomas Maximilian , Hader-Kregl Laura , Hafner Martina , Groiss Heiko , Duchoslav Jiri , Stifter David
Published: July 2023

In this study the oxide layer of technical 6xxx aluminium surfaces, pickled as well as passivated, were comparatively investigated by means of transmission electron microscopy (TEM), Auger electron and X-ray photoelectron spectroscopy (AES, XPS), the latter in two different operating modes, standard and angle resolved mode. In addition, confocal microscopy and focused ion beam cutting were used for structural studies of the surfaces and for specimen preparation. The results illustrate in detail the strengths and weaknesses of each measurement technique. TEM offers a direct way to reliably quantify the thickness of the oxide layer, which is in the range of 5 nm, however, on a laterally restricted area of the surface. In comparison, for AES, the destructiveness of the electron beam did not allow to achieve comparable results for the thickness determination. XPS was proven to be the most reliable method to reproducibly quantify the average oxide thickness. By evaluating the angle resolved XPS data, additional information on the average depth distribution of the individual elements on the surface could be obtained. The findings obtained in this study were then successfully used for the investigation of the increase in the aluminium oxide thickness on technical samples during an aging test of 12 months under standard storage conditions.
Hydrogen’s Effect on the Shape Memory Effect of TiNi Alloy Single Crystals
Authors: Kireeva Irina V. , Chumlyakov Yuriy I. , Yakovleva Liya P. , Vyrodova Anna V.
Published: July 2023

Hydrogen’s effect on the shape memory effect (SME) of [1¯17]-oriented Ti49.7-Ni50.3 (at.%) alloy single crystals, with a B2–B19′ martensitic transformation (MT), was studied after being electrolytically hydrogenated at a current density of 1500 A/m2 for 3 h at room temperature under isobaric tensile deformation. It was shown that, under the used hydrogenation regime, hydrogen was in a solid solution and lowered the elastic modulus of B19′ martensite. The hydrogen in a solid solution increased (i) the yield strength σ0.1 of the initial B2 phase by 100 MPa at Md temperature, (ii) the σ0.1 of the stress-induced B2–B19′ MT by 25 MPa at Ms temperature, and (iii) the plasticity of B19′ martensite relative to the hydrogen-free crystals. At the same level of external stresses, the SME in the hydrogenated crystals was greater than that in hydrogen-free crystals. At external tensile stresses σex = 200 MPa, the SME was 4.4 ± 0.2% in the hydrogenated crystals and 1.8 ± 0.2% without hydrogen. Hydrogen initiated a two-way SME of 0.5 ± 0.2% at σex = 0 MPa, which was absent in the hydrogen-free crystals. The physical reasons leading to an increase in the SME upon hydrogenation are discussed.
The Correlation of Kissing Bond, Microstructure and Mechanical Properties of the 2195 Al-Li Alloy Friction Stir Welding Joints at Different Welding Speeds
Authors: Chen Jiaxin , Liao Hongfei , Chen Rong , Tian Ye , Zhang Zhiqing , Liu Shifeng , Song Shoubo
Published: July 2023

Reasonable welding speeds are a prerequisite for obtaining high-quality joints by friction stir welding (FSW). In this paper, 2195-T8 Al-Li alloy FSW joints were successfully fabricated at different welding speeds (100–600 mm/min) with a constant rotation speed. The effect of welding speed on the microstructure and mechanical properties was analyzed under different experimental methods. Microstructural characterization was conducted using optical microscopy (OM), scanning electron microscopy (SEM), electron backscattered diffraction (EBSD) and transmission electron microscopy (TEM). Mechanical properties were measured by a hardness test and a tensile test. The results showed that the original T1 precipitates disappeared in the nugget zone (NZ), generating many dislocations. With welding speeds increasing, joints obtained at lower welding speeds developed coarser T1 precipitates in the heat-affected zone. Also, the equiaxed grains with a bigger size and a higher fraction of high angle boundaries (HABs) were detected in the NZ of these joints. As the welding speed increased, the area of hardness value changes gradually shrunk, which was consistent with the trend of the cross-section morphology. A kissing bond and macroscopic cracking were observed in the joints that were fabricated at the higher welding speeds. The appearance of those defects significantly reduced the ultimate tensile strength and elongation of the joints at high welding speeds. Fracture morphologies of the different joints were all characterized in quasi-cleavage fractures.
Novel In Vitro Assay of the Effects of Kampo Medicines against Intra/Extracellular Advanced Glycation End-Products in Oral, Esophageal, and Gastric Epithelial Cells
Authors: Takata Takanobu , Motoo Yoshiharu
Published: July 2023

Kampo medicines are Japanese traditional medicines developed from Chinese traditional medicines. The action mechanisms of the numerous known compounds have been studied for approximately 100 years; however, many remain unclear. While components are normally affected through digestion, absorption, and metabolism, in vitro oral, esophageal, and gastric epithelial cell models avoid these influences and, thus, represent superior assay systems for Kampo medicines. We focused on two areas of the strong performance of this assay system: intracellular and extracellular advanced glycation end-products (AGEs). AGEs are generated from glucose, fructose, and their metabolites, and promote lifestyle-related diseases such as diabetes and cancer. While current technology cannot analyze whole intracellular AGEs in cells in some organs, some AGEs can be generated for 1–2 days, and the turnover time of oral and gastric epithelial cells is 7–14 days. Therefore, we hypothesized that we could detect these rapidly generated intracellular AGEs in such cells. Extracellular AEGs (e.g., dietary or in the saliva) bind to the receptor for AGEs (RAGE) and the toll-like receptor 4 (TLR4) on the surface of the epithelial cells and can induce cytotoxicity such as inflammation. The analysis of Kampo medicine effects against intra/extracellular AGEs in vitro is a novel model.
The Pleiotropic Effects of Fumarate: From Mitochondrial Respiration to Epigenetic Rewiring and DNA Repair Mechanisms
Authors: Giallongo Sebastiano , Costa Francesco , Longhitano Lucia , Giallongo Cesarina , Ferrigno Jessica , Tropea Emanuela , Vicario Nunzio , Li Volti Giovanni , Parenti Rosalba , Barbagallo Ignazio , Bramanti Vincenzo , Tibullo Daniele
Published: July 2023

Tumor onset and its progression are strictly linked to its metabolic rewiring on the basis of the Warburg effect. In this context, fumarate emerged as a putative oncometabolite mediating cancer progression. Fumarate accumulation is usually driven by fumarate hydratase (FH) loss of function, the enzyme responsible for the reversible conversion of fumarate into malate. Fumarate accumulation acts as a double edge sword: on one hand it takes part in the metabolic rewiring of cancer cells, while on the other it also plays a crucial role in chromatin architecture reorganization. The latter is achieved by competing with a-ketoglutarate-dependent enzymes, eventually altering the cellular methylome profile, which in turn leads to its transcriptome modeling. Furthermore, in recent years, it has emerged that FH has an ability to recruit DNA double strand breaks. The accumulation of fumarate into damaged sites might also determine the DNA repair pathway in charge for the seizure of the lesion, eventually affecting the mutational state of the cells. In this work, we aimed to review the current knowledge on the role of fumarate as an oncometabolite orchestrating the cellular epigenetic landscape and DNA repair machinery.
An Ultra-Low-Power Analog Multiplier–Divider Compatible with Digital Code for RRAM-Based Computing-in-Memory Macros
Authors: Yang Yiming , Lv Shidong , Li Xiaoran , Wang Xinghua , Wang Qian , Yuan Yiyang , Liang Sen , Zhang Feng
Published: July 2023

This manuscript presents an ultra-low-power analog multiplier–divider compatible with digital code words, which is applicable to the integrated structure of resistive random-access memory (RRAM)-based computing-in-memory (CIM) macros. Current multiplication and division are accomplished by a current-mirror-based structure. Compared with digital dividers to achieve higher precision and operation speed, analog dividers present the advantages of a reduced power consumption and a simple circuit structure in lower precision operations, thus improving the energy efficiency. Designed and fabricated in a 55 nm CMOS process, the proposed work is capable of achieving 8-bit precision for analog current multiplication and division operations. Measurement results show that the signal delay is 1 μs when performing 8-bit operation, with a bandwidth of 1.4 MHz. The power consumption is less than 6.15 μW with a 1.2 V supply voltage. The proposed multiplier–divider can increase the operation capacity by dividing the input current and digital code while reducing the power consumption and complexity required by division, which can be further utilized in real-time operation of edge computing devices.
Growth of Nanocolumnar TiO2 Bilayer by Direct Current Reactive Magnetron Sputtering in Glancing-Angle Deposition Configuration for High-Quality Electron Transport Layer
Authors: Rosales Medina Perla Yanet , Avelar Muñoz Fernando , Flores Sigala Elida , Rosales Roberto Gómez , Berumen Torres Javier Alejandro , Araiza Ibarra José de Jesús , Tototzintle Huitle Hugo , Méndez García Víctor Hugo , Ortega Sigala José Juan
Published: July 2023

The electron transport layer (ETL) plays a crucial role in solar cell technology, particularly in perovskite solar cells (PSCs), where nanostructured TiO2 films have been investigated as superior ETLs compared to compact TiO2. In this study, we explored the nanocolumnar growth of TiO2 in the anatase phase for bilayer thin films by DC reactive magnetron sputtering (MS) technique and glancing-angle deposition (GLAD). For the growth of the compact TiO2 layer, it was found that the crystalline quality of the films is strongly dependent on the sputtering power, and the samples deposited at 120 and 140 W are those with the best crystalline quality. However, for the nanocolumnar layer, the reactive atmosphere composition determined the best crystalline properties. By optimizing the growth parameters, the formation of TiO2 nanocolumns with a cross-sectional diameter ranging from 50 to 75 nm was achieved. The average thickness of the films exceeded 12.71 ± 0.5 µm. All nanostructured films were grown at a constant GLAD angle of 70°, and after deposition, the measured inclination angle of the nanocolumns is very close to this, having values between 68 and 80°. Furthermore, a correlation was observed between the quality of the initial layer and the enhanced growth of the TiO2 nanocolumns. All bilayer films are highly transparent, allowing light to pass through up to 90%, and present a band gap with values between 3.7 and 3.8 eV. This article offers the experimental parameters for the fabrication of a nanocolumnar TiO2 using the magnetron sputtering technique and the glancing-angle deposition configuration.
Microbial Communities in Ferromanganese Sediments from the Northern Basin of Lake Baikal (Russia)
Authors: Lomakina Anna , Bukin Sergei , Shubenkova Olga , Pogodaeva Tatyana , Ivanov Vyacheslav , Bukin Yuri , Zemskaya Tamara
Published: July 2023

We analyzed the amplicons of the 16S rRNA genes and assembled metagenome-assembled genomes (MAGs) of the enrichment culture from the Fe-Mn layer to have an insight into the diversity and metabolic potential of microbial communities from sediments of two sites in the northern basin of Lake Baikal. Organotrophic Chloroflexota, Actionobacteriota, and Acidobacteriota, as well as aerobic and anaerobic participants of the methane cycle (Methylococcales and Methylomirabilota, respectively), dominated the communities of the surface layers. With depth, one of the cores showed a decrease in the proportion of the Chloroflexota and Acidobacteriota members and a substantial increase in the sequences of the phylum Firmicutes. The proportion of the Desulfobacteriota and Thermodesulfovibronia (Nitrospirota) increased in another core. The composition of archaeal communities was similar between the investigated sites and differed in depth. Members of ammonia-oxidizing archaea (Nitrososphaeria) predominated in the surface sediments, with an increase in anaerobic methanotrophs (Methanoperedenaceae) and organoheterotrophs (Bathyarchaeia) in deep sediments. Among the 37 MAGs, Gammaproteobacteria, Desulfobacteriota, and Methylomirabilota were the most common in the microbial community. Metagenome sequencing revealed the assembled genomes genes for N, S, and CH4 metabolism for carbon fixation, and genes encoding Fe and Mn pathways, indicating the likely coexistence of the biogeochemical cycle of various elements and creating certain conditions for the development of taxonomically and functionally diverse microbial communities.
Addressing Geological Challenges in Mineral Resource Estimation: A Comparative Study of Deep Learning and Traditional Techniques
Authors: Battalgazy Nurassyl , Valenta Rick , Gow Paul , Spier Carlos , Forbes Gordon
Published: July 2023

Spatial prediction of orebody characteristics can often be challenging given the commonly complex geological structure of mineral deposits. For example, a high nugget effect can strongly impact variogram modelling. Geological complexity can be caused by the presence of structural geological discontinuities combined with numerous lithotypes, which may lead to underperformance of grade estimation with traditional kriging. Deep learning algorithms can be a practical alternative in addressing these issues since, in the neural network, calculation of experimental variograms is not necessary and nonlinearity can be captured globally by learning the underlying interrelationships present in the dataset. Five different methods are used to estimate an unsampled 2D dataset. The methods include the machine learning techniques Support Vector Regression (SVR) and Multi-Layer Perceptron (MLP) neural network; the conventional geostatistical methods Simple Kriging (SK) and Nearest Neighbourhood (NN); and a deep learning technique, Convolutional Neural Network (CNN). A comparison of geologic features such as discontinuities, faults, and domain boundaries present in the results from the different methods shows that the CNN technique leads in terms of capturing the inherent geological characteristics of given data and possesses high potential to outperform other techniques for various datasets. The CNN model learns from training images and captures important features of each training image based on thousands of calculations and analyses and has good ability to define the borders of domains and to construct its discontinuities.
Three-Dimensional Geological–Geophysical Modeling and Prospecting Indications of the Ashele Ore Concentration Area in Xinjiang Based on Irregular Sections
Authors: Qi Guang , Meng Guixiang , Yan Jiayong , Tang Hejun , Xue Ronghui
Published: July 2023

The Ashele ore concentration area is an important area for polymetallic ore concentration in Xinjiang, China. Scholars have made progress in understanding the ore-controlling structures, ore-bearing horizons, and metallogenic age of this area. However, there are still uncertainties about the 3D distributions of plutons, fault structures, and ore-bearing strata, which restrict the development of deep and peripheral ore prospecting and the discovery of new ore bodies in the area. This study proposes a geological–geophysical modeling method based on irregular sections and uses this method to establish a 3D geological–geophysical model based on physical property data, boreholes, surface geological maps, and geophysical data. The model shows that the study area has many hidden rock masses with various depths and shapes and fracture structures with complex shapes. The fault structure in the area is complex, and the ore bodies are controlled by the faults. The ore-bearing geological units (Ashele Formation) exhibit an obvious east–west-trending W-shaped fold structure. The deep part of the northern Ashele Formation extends northward slightly, and the southern Ashele Formation has thick strata, with depths generally greater than 2 km. Based on the information on deep structures provided by the model, three metallogenic prospective areas are predicted, which points out the direction for further prospecting work in the ore concentration area and shows that the adopted modeling method and process have good applicability for constructing 3D models of ore concentration areas with sparse data, large area, and complex geological structures. The proposed modeling method provides technical support for ore prospecting, particularly in the overburden area or ore concentration area with sparse data.
Integration of Electrical Resistivity Tomography and Induced Polarization for Characterization and Mapping of (Pb-Zn-Ag) Sulfide Deposits
Authors: Ali Mosaad , Mewafy Farag , Qian Wei , Alshehri Fahad , Ahmed Mohamed , Saleem Hussein
Published: July 2023

The accurate characterization and mapping of low-grade ore deposits necessitate the utilization of a robust exploration technique. Induced polarization (IP) tomography is a powerful geophysical method for mineral exploration. An integrated survey using electrical resistivity tomography (ERT) and IP was employed in this study to characterize and map (Zn-Pb-Ag) ore deposits in NE New Brunswick, Canada. The survey encompassed twelve parallel lines across the study area. The 2D and 3D inversion of the results provided a detailed image of the resistivity and chargeability ranges of subsurface formations. The boundaries of sulfide mineralization were determined based on resistivity values of (700–2000 Ohm.m) and chargeability values of (3.5 mV/V) and were found to be located at an approximate depth of 80–150 m from the surface. The findings were validated through a comparison with data from borehole logs and mineralogy data analysis. The size and shape of sulfide deposits were successfully characterized and mapped in the study area using this cost-effective mapping approach.
Effect of Waste Clay Bricks on the Performance of Cemented Tailings Backfill and Its Damage Constitutive Model
Authors: Sun Tianxiang , Zhang Yifan , Wang Kang , Yu Zhuoqun , Wang Yongyan
Published: July 2023

In this study, two types of cemented tailings backfill (CTB) were prepared by breaking up the waste clay bricks (WCB) from dismantled buildings and replacing part of the cement with brick powder and part of the tailings with brick aggregate. The mechanical properties of the modified CTB were investigated. The results showed that the strength of CTB with 10% brick powder content increased by 16.24% at the curing age of 28 days, while the content of 20% brick powder only decreased by 0.11%. The strength of the brick aggregate with less than 20% content can be increased at each curing age, and the strength of the 15% brick aggregate at the curing age of 7 d and 28 d is increased by 65.54 and 58.8%. The failure strain of the CTB-containing brick powder decreases with the extension of the curing time, and the failure strain of the CTB-containing brick aggregate decreases significantly at the curing age of 7 days. In addition, a three-stage damage constitutive model was established based on the results obtained in the present study, and the laboratory test results of CTB under uniaxial compression were effectively described with high confidence.
Preparation and Performance Study of Microemulsion Acid for Comprehensive Plugging Removal in Carbonate Reservoir
Authors: Wang Yunjin , Zhou Fujian , Zou Yeping , Wang Zhenhua , Wang Yaocong
Published: July 2023

Matrix acidification is one of the most effective stimulations to dissolve scales and remove damage in carbonate reservoirs. However, existing acid systems are difficult to dissolve organic and inorganic scales simultaneously, and complex multi-stage alternative injection often introduces new precipitation and damages the reservoir. Here, based on the retardation ability of emulsified acid and the stable structure of microemulsion, an oil-phase solvent was preferably selected, and the surfactant and cosurfactant were optimized to prepare an acid-in-oil type microemulsion acid capable of dissolving both organic and inorganic scales and high solubilizing for hydrochloric acid. Based on the rotating disc experiment, scale dissolution experiment and acid driving experiment, the acid-rock reaction kinetics, scale dissolution ability and acidizing and plugging removal performance of microemulsion acid in a carbonate reservoir were systematically studied and compared. The results show that Solvesso 150 (aromatic solvent) has the advantages of low toxicity, high flash point and high-scale dissolving ability. At NP−4: OP−10: A (cosurfactant) = 3:3:4, the microemulsion acid system has the strongest ability to solubilize hydrochloric acid and can solve the problem of low H+ concentration. The particle size of microemulsion acid is smaller compared to emulsified acid. At 60 °C, the mass transfer coefficient of microemulsion acid is 3.2 × 10−8 cm2/s, which is one order of magnitude less than that of emulsified acid. Microemulsion acid shows good solubility performance in dissolving organic and inorganic scales, and the comprehensive solubility of mixed scales can reach 98.28%. The stronger scale solubilization ability and lower acid-rock reaction rate enable microemulsion acid to form a thin and straight main wormhole, thus enhancing the acidizing and plugging removal effect. This study can solve the problem of poor hydrochloric acid solubilization ability of microemulsion acid to a certain extent, which provides theoretical and data support for the research and development of microemulsion acid and the efficient plugging removal technology for carbonate reservoirs.
Tracing the Path between Mushrooms and Alzheimer’s Disease—A Literature Review
Authors: Silva Ana Margarida , Preto Marco , Grosso Clara , Vieira Mónica , Delerue-Matos Cristina , Vasconcelos Vitor , Reis Mariana , Barros Lillian , Martins Rosário
Published: July 2023

Alzheimer’s disease (AD) is well-known among neurodegenerative diseases for the decline of cognitive functions, making overall daily tasks difficult or impossible. The disease prevails as the most common form of dementia and remains without a well-defined etiology. Being considered a disease of multifactorial origin, current targeted treatments have only managed to reduce or control symptoms, and to date, only two drugs are close to being able to halt its progression. For decades, natural compounds produced by living organisms have been at the forefront of research for new therapies. Mushrooms, which are well-known for their nutritional and medicinal properties, have also been studied for their potential use in the treatment of AD. Natural products derived from mushrooms have shown to be beneficial in several AD-related mechanisms, including the inhibition of acetylcholinesterase (AChE) and β-secretase (BACE 1); the prevention of amyloid beta (Aβ) aggregation and neurotoxicity; and the prevention of Tau expression and aggregation, as well as antioxidant and anti-inflammatory potential. Several studies in the literature relate mushrooms to neurodegenerative diseases. However, to the best of our knowledge, there is no publication that summarizes only AD data. In this context, this review aims to link the therapeutic potential of mushrooms to AD by compiling the anti-AD potential of different mushroom extracts or isolated compounds, targeting known AD-related mechanisms.
Arabinoxylan from Corn Fiber Obtained through Alkaline Extraction and Membrane Purification: Relating Bioactivities with the Phenolic Compounds
Authors: Weng Verónica , Cardeira Martim , Bento-Silva Andreia , Serra Ana Teresa , Brazinha Carla , Bronze Maria Rosário
Published: July 2023

Arabinoxylan has prebiotic properties, as it is able to resist digestion in the small intestine and undergoes fermentation in the large intestine. In this work, arabinoxylan was extracted from corn fiber using an alkaline solution and further purified with membrane processing. It was found that the extracts were mainly composed of xylose (50–52%), arabinose (37–39%), galactose (9%) and glucose (1–4%), with an A/X ratio of 0.72–0.77. All the extracts were composed of phenolic compounds, including ferulic acid derivatives such as dimers, trimers and tetramers. The purified extract had a lower concentration of ferulic and p-coumaric acid (0.004 and 0.02 mg/mgdry_weight, respectively) when compared to raw extract (19.30 and 2.74 mg/mgdry_weight, respectively). The same effect was observed for the antioxidant activity, with purified extracts having a lower value (0.17 ± 0.02 µmol TEAC/mg) when compared to the raw extract (2.20 ± 0.35 µmol TEAC/mg). The purified extract showed a greater antiproliferative effect against the HT29 cell line with EC50 = 0.12 ± 0.02 mg/mL when compared to the raw extract (EC50 = 5.60 ± 1.6 mg/mL). Both raw and purified extracts did not show any cytotoxicity to the Caco-2 cell line in the maximum concentration tested (10 mg/mL).
Limb–Girdle Muscular Dystrophy D2 TNPO3-Related: A Quality of Life Study
Authors: Rodríguez Alicia Aurora , Amayra Imanol , García Irune , Angelini Corrado
Published: July 2023

The present study is the first research that analyzes the quality of life (QoL) of people affected by a dominant form of limb–girdle muscular dystrophy, specifically limb–girdle muscular dystrophy D2 (LGMD-D2). Additionally, clinical forms of the individual cases of the six affected patients are presented. This study also aims to explore the differences between patients’ reports and caregivers’ reports, and between LGMD-D2 and recessive forms of LGMD. The instruments used were as follows: sociodemographic data, GSGC, and INQoL instrument. The sample consisted of six people affected by LGMD-D2: three caregivers of three affected people, and three patients with recessive LGMD. They came from associations of affected people and a hospital in Padua. Those affected have multiple symptoms that lead to disability, which ultimately leads to dependence on the assistance. The present study shows that LGMD-D2 has a greater impact on activities of daily living, fatigue, muscle pain, and independence than other LGMD pathologies or other neuromuscular diseases. It also appears that age could influence QoL, and that muscle weakness is a very disabling symptom in this variant. In the current context of constantly developing research for new treatments, it is essential to analyze which aspects are most affected. Finally, caregivers can play an essential role in symptom reporting, as certain psychological adjustment mechanisms in the patient may be interfering with the objectivity of the report.
Switchable and Tunable Terahertz Metamaterial Based on Vanadium Dioxide and Photosensitive Silicon
Authors: Zhang Xin , Wang Guan , Liu Jia , Zuo Shiyi , Li Meichen , Yang Shuang , Jia Yang , Gao Yachen
Published: July 2023

A switchable and tunable terahertz (THz) metamaterial based on photosensitive silicon and Vanadium dioxide (VO2) was proposed. By using a finite-difference time-domain (FDTD) method, the transmission and reflective properties of the metamaterial were investigated theoretically. The results imply that the metamaterial can realize a dual electromagnetically induced transparency (EIT) or two narrow-band absorptions depending on the temperature of the VO2. Additionally, the magnitude of the EIT and two narrow-band absorptions can be tuned by varying the conductivity of photosensitive silicon (PSi) via pumping light. Correspondingly, the slow-light effect accompanying the EIT can also be adjusted.
Silica Encapsulation of Hydrophobic Optical NP-Embedded Silica Particles with Trimethoxy(2-Phenylethyl)silane
Authors: Hahm Eunil , Jo Ahla , Kang Eunji , Yoo Kwanghee , Shin Minsup , An Jaehyun , Pham Xuanhung , Kim Hyungmo , Kang Homan , Kim Jaehi , Jun Bonghyun
Published: July 2023

Nanoparticles (NP) with optical properties embedded silica particles have been widely used in various fields because of their unique properties. The surfaces of optical NPs have been modified with various organic ligands to maintain their unique optical properties and colloidal stability. Among the surface modification methods, silica encapsulation of optical NPs is widely used to enhance their biocompatibility and stability. However, in the case of NPs with hydrophobic ligands on the surface, the ligands that determine the optical properties of the NPs may detach from the NPs, thereby changing the optical properties during silica encapsulation. Herein, we report a generally applicable silica encapsulation method using trimethoxy(2-phenylethyl)silane (TMPS) for non-hydrophilic optical NPs, such as quantum dots (QDs) and gold NPs. This silica encapsulation method was applied to fabricate multiple silica-encapsulated QD-embedded silica NPs (SiO2@QD@SiO2 NPs; QD2) and multiple silica-encapsulated gold NP-embedded silica NPs labeled with 2-naphthalene thiol (SiO2@Au2-NT@SiO2). The fabricated silica-encapsulated NPs exhibited optical properties without significant changes in the quantum yield or Raman signal intensity.
Mechanism of the Wake-Up and the Split-Up in AlOx/Hf0.5Zr0.5Ox Film
Authors: Kim Min-Jin , Kim Cheol-Jun , Kang Bo-Soo
Published: July 2023

Dielectric layers are widely used in ferroelectric applications such as memory and negative capacitance devices. The wake-up and the split-up phenomena in the ferroelectric hafnia are well-known challenges in early-stage device reliability. We found that the phenomena even occur in the bilayer, which is composed of the hafnia and the dielectrics. The phenomena are known to be affected mainly by oxygen vacancies of hafnia. Dielectric layers, which are often metal oxides, are also prone to be affected by oxygen vacancies. To study the effect of the dielectric layer on the wake-up and the split-up phenomena, we fabricated ferroelectric thin-film capacitors with dielectric layers of various thicknesses and measured their field-cycling behaviors. We found that the movement of oxygen vacancies in the dielectric layer was predominantly affected by the polarization state of the ferroelectric layer. In addition, the mechanism of the field-cycling behavior in the bilayer is similar to that in ferroelectric thin films. Our results can be applied in ferroelectric applications that use dielectric layers.
Landau Diamagnetism and de Haas–van Alphen Oscillations, Formed in Single Crystals of Y3Fe5O12, in Local Nanodimensional-Sized 2D Phase Separation Regions, Located inside Layered Domain Walls at Room Temperature and T = 77 K
Authors: Khannanov Boris , Golovenchits Evgeny , Shcheglov Mikhail , Sanina Viktoriya
Published: July 2023

This paper presents results of the magnetic dynamics study (the microwave power absorptions at the fixed frequencies during magnetic field sweeping) in samples of Y3Fe5O12 single crystals in the form of plates and spheres of various sizes, at frequencies exceeding 30 GHz, in magnetic fields up to 18 kOe, at room temperature, and T = 77 K. It was found that in this case, the inhomogeneity’s of the magnetic state manifested itself in the Y3Fe5O12 samples as 2D local phase separation regions. Such 2D phase separation regions formed inside layered domain walls representing superlattices with sizes of 700–900 Å. Depending on the shape and size of the studied plates and spheres, Landau diamagnetism or de Haas–van Alphen oscillations were observed in the 2D phase separation regions at room temperature and T = 77 K.
The Effect of Mono and Hybrid Additives of Ceramic Nanoparticles on the Tribological Behavior and Mechanical Characteristics of an Al-Based Composite Matrix Produced by Friction Stir Processing
Authors: Moustafa Essam B. , Taha Mohammed A.
Published: July 2023

Friction stir processing (FSP) is an effective method for incorporating ceramic nanoparticles into metal matrix composites. This study investigated the effects of single and multiple additions of BN, VC, and SiC nanoparticles on the microstructure refinement and tribological behavior of an AA2024 alloy-based nanocomposite matrix fabricated by FSP. The results showed that adding ceramic nanoparticles, either singly or in combination, led to significant refinement of grain structure and improved wear resistance of the AA2024 alloy-based nanocomposite matrix. Additionally, the study found that combining BN, SiC, and VC nanoparticles produced the most effective effects on refining and reducing grain size. The microhardness behavior of the composite surface resulting from the hybrid particles showed a significant improvement, reaching 94% more than the base alloy. Overall, these results indicate that the multiple additions of ceramic nanoparticles by FSP are a promising approach to improve aluminum alloys’ tribological behavior and mechanical properties.
Second Harmonic Generation in Janus Transition Metal Chalcogenide Oxide Monolayers: A First-Principles Investigation
Authors: Su Peng , Ye Han , Sun Naizhang , Liu Shining , Zhang Hu
Published: July 2023

Due to the unique optical responses induced by vertical atomic asymmetry inside a monolayer, two-dimensional Janus structures have been conceived as promising building blocks for nanoscale optical devices. In this paper, second harmonic generation (SHG) in Janus transition metal chalcogenide oxide monolayers is systematically investigated by the first-principles calculations. Second-order nonlinear susceptibilities are theoretically determined for Janus MXO (M = Mo/W, X = S/Se/Te) monolayers. The calculated values are comparable in magnitude with Janus MoSSe monolayer. X-M-O symmetry breaking leads to non-zero components in vertical direction, compared with the non-Janus structure. Focusing on the SHG induced by incident light at 1064 nm, polarization-dependent responses of six Janus MXO monolayers are demonstrated. The symmetry of p-polarization changes from six-fold to three-fold with acute incidence angle. Moreover, the effects of biaxial strain on band structures and SHG are further investigated, taking MoSO as an exemplary case. We expect these results to bring in recipes for designing nonlinear optical devices based on Janus transition metal chalcogenide oxide monolayers.
Evolution of Mn1−xGexBi2Te4 Electronic Structure under Variation of Ge Content
Authors: Estyunina Tatiana P. , Shikin Alexander M. , Estyunin Dmitry A. , Eryzhenkov Alexander V. , Klimovskikh Ilya I. , Bokai Kirill A. , Golyashov Vladimir A. , Kokh Konstantin A. , Tereshchenko Oleg E. , Kumar Shiv , Shimada Kenya , Tarasov Artem V.
Published: July 2023

One of the approaches to manipulate MnBi2Te4 properties is the magnetic dilution, which inevitably affects the interplay of magnetism and band topology in the system. In this work, we carried out angle-resolved photoemission spectroscopy (ARPES) measurements and density functional theory (DFT) calculations for analysing changes in the electronic structure of Mn1−xGexBi2Te4 that occur under parameter x variation. We consider two ways of Mn/Ge substitution: (i) bulk doping of the whole system; (ii) surface doping of the first septuple layer. For the case (i), the experimental results reveal a decrease in the value of the bulk band gap, which should be reversed by an increase when the Ge concentration reaches a certain value. Ab-initio calculations show that at Ge concentrations above 50%, there is an absence of the bulk band inversion of the Te pz and Bi pz contributions at the Γ-point with significant spatial redistribution of the states at the band gap edges into the bulk, suggesting topological phase transition in the system. For case (ii) of the vertical heterostructure Mn1−xGexBi2Te4/MnBi2Te4, it was shown that an increase of Ge concentration in the first septuple layer leads to effective modulation of the Dirac gap in the absence of significant topological surface states of spatial redistribution. The results obtained indicate that surface doping compares favorably compared to bulk doping as a method for the Dirac gap value modulation.
An Up-to-Date Review on the Remediation of Dyes and Phenolic Compounds from Wastewaters Using Enzymes Immobilized on Emerging and Nanostructured Materials: Promises and Challenges
Authors: Al-Sakkaf Mohammed K. , Basfer Ibrahim , Iddrisu Mustapha , Bahadi Salem A. , Nasser Mustafa S. , Abussaud Basim , Drmosh Qasem A. , Onaizi Sagheer A.
Published: July 2023

Addressing the critical issue of water pollution, this review article emphasizes the need to remove hazardous dyes and phenolic compounds from wastewater. These pollutants pose severe risks due to their toxic, mutagenic, and carcinogenic properties. The study explores various techniques for the remediation of organic contaminants from wastewater, including an enzymatic approach. A significant challenge in enzymatic wastewater treatment is the loss of enzyme activity and difficulty in recovery post-treatment. To mitigate these issues, this review examines the strategy of immobilizing enzymes on newly developed nanostructured materials like graphene, carbon nanotubes (CNTs), and metal–organic frameworks (MOFs). These materials offer high surface areas, excellent porosity, and ample anchoring sites for effective enzyme immobilization. The review evaluates recent research on enzyme immobilization on these supports and their applications in biocatalytic nanoparticles. It also analyzes the impact of operational factors (e.g., time, pH, and temperature) on dye and phenolic compound removal from wastewater using these enzymes. Despite promising outcomes, this review acknowledges the challenges for large-scale implementation and offers recommendations for future research to tackle these obstacles. This review concludes by suggesting that enzyme immobilization on these emerging materials could present a sustainable, environmentally friendly solution to the escalating water pollution crisis.
Introduce Ce3+ Ions to Realize Enhancement of C+L Band Luminescence of KMnF3: Yb, Er Nanoparticles
Authors: Cui Hao , Li Daguang , Yang Yu , Fu Yuewu , Dong Yanhui , Yin Jing , Qin Weiping , Jia Zhixu , Zhao Dan
Published: July 2023

Polymer-based waveguide amplifiers are essential components in integrated optical systems, as their gain bandwidths directly determine the operating wavelength of optical circuits. However, development of the wideband gain media has been challenging, making it difficult to fabricate devices with broadband amplification capability. Rare earth ion-doped nanoparticles (NPs) are a key component in the gain media, and their full width at half maximum (FWHM) of the emission peak decides the final gain bandwidth of the gain media. Here, KMnF3: Yb, Er, Ce@KMnF3: Yb NPs with the broad full width at half maximum (FWHM) of the emission peak covering the S+C band was prepared. The NPs were synthesized using a hydrothermal method, and the FWHM of the emission peak of NPs reached 76 nm under the excitation of a 980 nm laser. The introduction of Ce3+ ions and a core-shell structure coating greatly enhanced the emission intensity of NPs at C band. Since KMnF3: Yb, Er, Ce@KMnF3: Yb NPs have exceptional broadband luminescence properties at C band, KMnF3: Yb, Er, Ce@KMnF3: Yb NPs can be the potential gain medium in the future polymer-based waveguide amplifiers.
Associations between Total and Added Sugar Intake and Diabetes among Chinese Adults: The Role of Body Mass Index
Authors: Liu Yan , Cheng Jing , Wan Lijin , Chen Wei
Published: July 2023

Sugar intake has been linked to the global rise in diabetes. However, the unique diabetogenic effect of sugar, independent of weight gain, remains controversial. This study aimed to investigate the associations between total and added sugar intake and diabetes status, and to test whether the sugar–diabetes associations were moderated or mediated by the body mass index (BMI). We performed a nationwide cross-sectional study on 12,889 Chinese adults who were enrolled in the China Health and Nutrition Survey (CHNS) 2011. The data for the total and added sugar intake were measured using three consecutive 24 h recalls, and determined based on the U.S. Department of Agriculture (USDA) National Nutrient Database for Standard Reference, Release 28 (SR28), the Food Patterns Equivalents Database (FPED) 2015–2016, and the labeled ingredients and nutrient contents. A multivariable logistic regression model was used to analyze the associations between the total and added sugar intake and diabetes. A nutrient density model was used to adjust for the total energy intake. A mediation analysis for significant sugar–diabetes associations shown in multivariable logistic analysis (p < 0.05), and a subgroup analysis according to the BMI category were performed, to examine the mediating and moderating effects of the BMI on the sugar–diabetes association, respectively. We included 12,800 individuals, with a mean age of 50.5, in the final analysis. The means of the total and added sugar intake, total sugar (%E), and added sugar (%E) were 28.2 ± 0.2 g/d, 5.0 ± 0.1 g/d, 6.0 ± 0.0%, and 1.0 ± 0.0%, respectively. The overall prevalence of self-reported physician-diagnosed diabetes was 4.0%. A significant association between the total sugar intake and an increased risk of diabetes was found (odds ratio [OR] =1.008, 95% CI 1.001–1.016). The mediation analysis showed a significant mediation effect through the BMI of the effect of the total sugar on diabetes status (p < 0.001), where 11.7% (95% CI: 4.7–35.7%) of the effect of the total sugar on diabetes was mediated through the BMI. The total sugar intake had a significant direct effect on diabetes around the BMI (estimated coefficient = 0.0004, p < 0.001). The overall total-sugar-intake–diabetes association remained significant in normal-weight participants in the subgroup analysis (OR =1.012, 1.000–1.024). In conclusion, although the BMI moderated and mediated the association between the total sugar intake and diabetes, the total sugar still showed some unique weight-independent diabetogenic effects. Our findings call for efforts to prevent and control diabetes by reducing sugar intake, and losing weight appropriately.
The Prevalence and Impact of Nutritional Risk and Malnutrition in Gastrointestinal Surgical Oncology Patients: A Prospective, Observational, Multicenter, and Exploratory Study
Authors: Durán Poveda Manuel , Suárez-de-la-Rica Alejandro , Cancer Minchot Emilia , Ocón Bretón Julia , Sánchez Pernaute Andrés , Rodríguez Caravaca Gil
Published: July 2023

A prospective, observational, multicenter, and exploratory study was conducted in 469 gastrointestinal cancer patients undergoing elective surgery. The Malnutrition Universal Screening Tool (MUST) and the Global Leadership Initiative on Malnutrition (GLIM) criteria were used to assess nutritional risk. On admission, 17.9% and 21.1% of patients were at moderate (MUST score 1) and severe (MUST score ≥ 2) nutritional risk, respectively. The GLIM criteria used in patients with a MUST score ≥ 2 showed moderate malnutrition in 35.3% of patients and severe in 64.6%. Forty-seven percent of patients with a MUST score ≥ 2 on admission had the same score at discharge, and 20.7% with a MUST score 0 had moderate/severe risk at discharge. Small bowel, esophageal, and gastric cancer and diabetes were predictors of malnutrition on admission. Complications were significantly higher among patients with a MUST score 1 or ≥2 either on admission (p = 0.001) or at discharge (p < 0.0001). In patients who received nutritional therapy (n = 231), 43% continued to have moderate/severe nutritional risk on discharge, and 54% of those with MUST ≥ 2 on admission maintained this score at discharge. In gastrointestinal cancer patients undergoing elective surgery, there is an urgent need for improving nutritional risk screening before and after surgery, as well as improving nutritional therapy during hospitalization.
Pulsed-Field Gel Electrophoresis Analysis of Bovine Associated Staphylococcus aureus: A Review
Authors: Dendani Chadi Zoubida , Arcangioli Marie-Anne
Published: July 2023

For decades now, DNA fingerprinting by means of pulsed-field gel electrophoresis (PFGE) continues to be the most widely used to separate large DNA molecules and distinguish between different strains in alternating pulses. This is done by isolating intact chromosomal DNA and using restriction enzymes with specific restriction sites to generate less than 30 restriction fragments from 50 Kb to 10 Mbp. These results make clone-specific band profiles easy to compare. Specialized equipment is required for the optimization of DNA separation and resolution, among which a contour-clamped homogeneous electric field (CHEF) apparatus is the most commonly used. As a result, the PFGE analysis of a bacterial genome provides useful information in terms of epidemiological investigations of different bacterial pathogens. For Staphylococcus aureus subtyping, despite its limitations and the emergence of alternative methods, PFGE analysis has proven to be an adequate choice and the gold standard for determining genetic relatedness, especially in outbreak detection and short-term surveillance in the veterinary field.
Molecular Identification and Characterization of Fusarium Associated with Walnut Branch Blight Disease in China
Authors: Ma Ting , Yang Chengde , Cai Fengfeng , Osei Richard
Published: July 2023

In October 2020, samples of walnut branch blight were collected from Longnan. Pathogens were isolated and identified based on morphological and molecular features, and their characteristics were analyzed by pathogenicity. Pathogenicity testing revealed that seven strains (LN-1, LN-3, LN-6, LN-19, LN-27, QY3-1, and QY9-1) induced symptoms of walnut branch blight that were consistent with those observed in the field after inoculation. Furthermore, some Fusarium-type conidia and spherical chlamydospores were visible indicating that they were Fusarium spp. A molecular characterization including sequence and phylogenetic analysis of the ITS, TEF-1α, βTUB, Fu, and LSU gene regions revealed that LN-1 and LN-19 belonged to F. avenaceum, LN-3 and LN-6 to F. acuminatum, LN-27 to F. sporotrichioides, and QY3-1 and QY9-1 to F. tricinctum. This is the first time that F. acuminatum-, F. sporotrichioides-, and F. tricinctum-caused walnut branch blight has been reported in China.