bluuebunny/crossref_metadata_2025 huggingface dataset:
Frequency of etiologies of acute kidney injury in Faisalabad and surrounding districts
Authors: Farid Muhammad A. , Khan Rizwan R. , Azhar Salman , Saqib Ali , Ahmad Imran N. , Baig Muhammad W.
Published: November 2019

Background: To find out the causes of Acute Kidney Injury (AKI) in population.Methods: A total of 150 patients were enrolled from medical, surgical, gynecology and obstetrics units of Allied Hospital and Madinah Teaching Hospital, Faisalabad, Pakistan. History, physical examination and investigations were recorded on specially designed proforma. Patients were evaluated to find out the etiologies of AKI. All patients were subjected to urine analysis, complete blood count, blood biochemistry (urea, creatinine, electrolytes, uric acid, calcium and phosphorus) and ultrasound scan of the abdomen and pelvis. Renal biopsy, immunological assays, such as hepatitis B surface antigen, anti-hepatitis C virus antibody, complements level, antinuclear antibody, anti-double-stranded DNA, anti-neutrophil cytoplasmic antibody and anti-glomerular basement membrane antibody were performed in selected cases.Results: Male (36%) and female (64%). Pre-renal AKI was most common and was reported in 80 patients (53.33%). Intrinsic Renal azotemia in 56 patients (37.33%). Post renal azotemia in 14 patients (9.33%). Among 80 patients of prerenal AKI, hemorrhage in 45(56.25%), gastroenteritis in 16(20%), sepsis in 8(10%), cardiac diseases in 4(5%), hepatorenal syndrome in 3 (3.75%), peritonitis in 2 (2.50%) and burns in 2(2.50%) were the main causes of Pre-renal AKI. Among 56 patients of intrinsic renal AKI, 40(71.4%) had acute tubular necrosis (ATN), 12(21.4%) with multifactorial causes and 4(7.14%) were found to have glomerulonephritis. Among 14 patients of post renal AKI, 6(42.9%) were having calculi, 6(42.9%) were to have enlarged prostate and 2(4.3%) were having stricture urethra. In this study, contribution of obstetrical, medical and surgical etiologies were recorded as 40%, 36% and 20% respectively.Conclusions: In contrast to study reported from neighbouring country, this study shows rather increase in pregnancy related AKI.
Prevalence and pattern of hypertension among elderly in Osun state, Nigeria
Authors: Egbewale Bolaji Emmanuel , Oyekale Adesola Oyekunle , Adedokun Samuel Adeyinka , Akindele Akeem Abiodun , Adejimi Adebola Afolake
Published: November 2019

Background: Hypertension is a major public health challenge worldwide. It is acknowledged as an important risk factor for cardiovascular morbidity and mortality, particularly among the elderly. This study aimed to investigate the prevalence and pattern of hypertension among the elderly in Osun state, Nigeria.Methods: A descriptive cross-sectional design was used. The study involved 425 respondents aged 60 years and above selected randomly in five local government areas in Osun state. The blood pressure was measured (using a standardized Accoson® type pneumatic mercury sphygmomanometer); weight and height of the respondents were checked and recorded in mmHg, Kg and meters respectively. Data were presented using descriptive statistics, charts and frequency distribution table. Statistical association between categorical variables was assessed using Chi-square method at 5% level of significance.Results: Prevalence of hypertension among elderly was 44.7%. Among other factors, respondents’ body mass index BMI was found significantly associated with hypertension, p=0.009. However, prevalence of hypertension was higher for respondents that were; rural dwellers, female, not living with spouse, without viable source of income and engaging in little or no physical activity compared to their counterparts. Respondent’s BMI and sex were also found to be statistically significantly associated, p=0.011.Conclusions: Prevalence of hypertension was high among the elderly in this study. Health interventions aimed at reducing the diseases should encourage increased physical activities and incorporate financial empowerment schemes particularly for elderly women in rural settings.
Domestic injuries among geriatric population: a study in a rural community of Bankura district
Authors: De Arindam , Padmey Indu , Halder Debakar , Gazi Eashin , Sarkar Aditya Prasad , Basu Subhra Samujjwal
Published: November 2019

Background: Domestic injury is an injury, which takes place in the home or in its immediate surroundings and more generally, all injury not connected with traffic, vehicles or sport. It is a worldwide public health problem. Geriatric population is more vulnerable to domestic injury. Objectives of this study are to estimate the incidence and to identify the correlates, if any, of domestic injuries among geriatric population and to study the consequences of domestic injuries among study subjects.Methods: Community-based descriptive study with longitudinal design. Multistage random sampling was adopted in the study. One block was selected by simple random sampling method then cluster sampling method (30/7) was used considering village as cluster. Three cross-sectional surveys were conducted in study subjects. Data was collected with the help of pre-designed, pre-tested, semi-structured schedule by paying house-to-house visits and review of records.Results: The subjects under study comprised of 210 elderly individuals, out of which 27 faced domestic injuries and three study subjects faced injury twice in study period. So, total number of injured was 30. Incidence rate was calculated to be 142.85 injuries per thousand persons per year. Fall was most common type of domestic injury. According to the consequence of injury, impairment was found in 13 cases out of them two injured cases were suffered from permanent disability.Conclusions: Incidence was estimated to be higher than what was found in other studies. Fall was the most common type of domestic injury. Marital status, use of central nervous system depressant drugs and co-morbidities were found to have positive association with injury.
A cross sectional study to determine the health profile of brick kiln workers
Authors: Kazi Rufiat N. , Bote Mangala M.
Published: November 2019

Background: Occupational hazards involving the respiratory system, musculoskeletal system, skin and eyes are very commonly seen in the workers involved in the brick kiln industry. This study was designed to assess health profile of the brick kiln workers and to discuss sociodemographic profile affecting their health.Methods: This was a cross sectional study. 420 workers falling into the eligibility criteria, were selected from the 65 brick kiln factories in the study area. Multi-stage cluster sampling method was used to select the brick kiln factories and the participants of the study. The responses given by the participants were entered in Microsoft Excel 2010 and analyzed using SPSS version 20. Chi Square test was used to determine the association between the morbidities and sociodemographic variables.Results: Mean age of the workers was 35.34±10.96 years. 96.7% of the respondents were suffering from some or the other complaints, while 3.3% were not suffering from any complaints. Addiction was seen in 37.9% of the participants. Musculoskeletal complaints were the most common complaints followed by respiratory and skin complaints.Conclusions: Health of workers is affected due to conditions they work under. The older age group had more respiratory, dermatological and ophthalmic complaints. The group of workers employed as bigaaris as well as those who were working for more than 10 years had more respiratory and dermatological complaints.
Comparison of effect of concurrent phone texting on gait speed in young and middle aged healthy subjects
Authors: Shah Vaibhavi R. , Sheth Megha S.
Published: November 2019

Background: Around the world today, adoption of mobile media phones and its advancement have been growing at dizzying pace in all age groups. People use phone while walking on/crossing roads, climbing stairs, driving cars, etc. Using a smartphone while walking has shown decrease in walking speed and affect dynamic balance by reducing cognitive ability. The objective of study is to see and compare effect of concurrent phone texting while obstacle walking on walking time in young and middle-aged healthy subjects.Methods: An observational study with 100 healthy individuals (50 young and 50 middle-aged) were taken and had to walk on a 15 m walkway with obstacle (approximately 10% of subject’s height) at 8m distance from start without and with texting. The text messages used were all short objective questions and were sent to them approximately 2 steps prior to reaching the obstacle. Their walking time was analyzed.Results: Wilcoxon test used to analyze difference within group. In young people without phone texting it was11.41±1.24 seconds and with texting was14.79±2.67seconds, (z=-6.101, p<0.001) and in middle aged was14.93±1.20 seconds and 20.52±1.87 seconds respectively (z=-6.154, p<0.001). Mann Whitney test used to analyze difference between groups. For without texting in young and middle aged walking time (U=48.0, p<0.001), with texting young and middle aged walking time (U=122.00, p<0.001) and comparing the difference in walking time between young and middle aged with and without phone texting (U=372.5, p<0.001).Conclusions: Phone texting increases walking time in young and middle aged with difference in walking time more in middle aged adults.
Doctor shopping behaviour and its determinants among people with chronic diseases in rural Kancheepuram district, Tamil Nadu: a cross-sectional study
Authors: Tharumaraj Muthukumar , Annadurai Kalaivani , Cinthiya Jerrin , Ranganathan Karnaboopathy
Published: November 2019

Background: Doctor shopping is defined as the practice of patient seeking multiple health care providers without making efforts to coordinate care or informing physicians of the multiple care givers for the same illness or to procure prescription drugs illicitly. This study was planned to explore the doctor shopping behaviour and its determinants among people with chronic diseases in rural Kancheepuram district, Tamil Nadu.Methods: A cross sectional study was conducted among patients of chronic diseases residing in Sembakkam village, Kancheepuram District, Tamil Nadu. Data was collected using a pre-tested semi-structured schedule adopted from Agarwal et al will be used.Results: Prevalence of doctor shopping was found to be 73.7% among the study population which is visiting more than one doctor for the same diagnosis. The main reason given by the participants for consulting more than one doctor was consistence of the symptoms (34%) followed by location of the health facility (15.9%) and non-acceptance of the diagnosis (15.5%).Conclusions: Patient education, good interpersonal communication skills, and health system strengthening measures can increase responsiveness of the community toward the health systems and thereby reduce doctor shopping behaviour.
Knowledge of disaster preparedness among medical professionals in JNU Institute for Medical Sciences and Research Centre, Jaipur, Rajasthan
Authors: Tiwari Nitin , Bankwar Vishal , Jha Ranjit K. , Singh Aryak
Published: November 2019

Background: Disaster causes widespread destruction, disrupting people's lives and causing human suffering with communities finding it difficult to cope. Human beings may not have the power to stop it but they may have the ability to be prepared and minimize the impact of the disaster. The medical professionals play a pivotal role in a disaster situation and its knowledge is a must during their academics. This study was aimed to assess the level of knowledge of disaster preparedness among medical professionals.Methods: A cross-sectional study was conducted among the medical professionals in JNUIMSRC, Jaipur, Rajasthan. A total of 225 people were selected and interviewed. Data was collected using self-administered semi-structured questionnaire and scoring was done for the assessment of knowledge on disaster preparedness. Epi-info software version 7.2.3.1 was used for statistical analysis.Results: Out of a total of 225 respondents, 140 were females and 85 were males. The mean age of respondents was 20±0.58 and most of them were in the 18-24 years age-group (61.33%). A total of 191 (88.9%) respondents had either partial or total lack of knowledge regarding disaster preparedness. Most of the respondents, 195 (86.67%) had a view that there is a need to introduce disaster preparedness training program.Conclusions: The findings revealed that most of the study participants had not attended any training on disaster management and most of them had low knowledge about disaster preparedness. The integration of disaster education into the curriculum is believed to be the most effective strategy.
An assessment of facilities and services at anganwadi centers under the integrated child development service scheme in urban area of Kathua district, Jammu and Kashmir
Authors: Kapoor Anuj , Singh Kamna
Published: November 2019

Background: The integrated childhood development services (ICDS) scheme, launched on 2nd November 1975 is India’s foremost program imparting comprehensive and cost-effective services for children and maternal health through designated anganwadi centers (AWCs). AWCs deliver services right at the doorsteps of the beneficiaries to ensure their maximum participation.Methods: This was a cross sectional descriptive study conducted in 37 AWCs of the urban area in Kathua district from March to May 2019. A checklist was used to assess the physical infrastructure of AWC and logistics available.Results: A total of 37 AWCs were visited. Majority of the AWCs (94.5%) were running in a rented building and had only room. and 86.4% have pucca type of center. Almost half (51.3%) of the anganwadi workers had >10 years of experience. 32.4% of the AWWs received education up to 12th standard. Weighing machines were available in 89.1% of the centers whereas Salter weighing machine was present only in 23 centers.Conclusions: Present case study unveils deficiencies in infrastructure and logistics at the centers. Emphasis should be given to strengthen the basic infrastructure of AWCs which would further help in delivering quality services to the beneficiaries.
Analysing maternal determinants and characteristics of obstetric referrals at a tertiary care centre in Kerala, India
Authors: T. Heera Shenoy , T. Sheela Shenoy , Krishnan Remash
Published: November 2019

Background: Timely and prompt referral of high risk pregnancies is an integral part of emergency obstetric care and is one of the effective strategies to avoid adverse pregnancy outcomes. This study aims to assess the maternal determinants and characteristics of obstetric referrals to Travancore Medical College and Hospital.Methods: This observational study reviewed 124 obstetric referrals over 3 years. Maternal risk factors and sources of referral were looked into. Distance travelled, referral-arrival interval, mode of transport, gestational age at referral, medical co-morbidities necessitating emergency/elective transfers to this tertiary centre have been analysed.Results: Referral rate was 7.03%. Mean age was 26. Primipara and multipara went hand in hand. 95% were graduates. Materno-fetal (58%) contributed the bulk of obstetric referrals. 83.1% were from private hospitals and 64 were in-labour referrals. 71.6% had referral arrival distance of <15 kms. Mode of transport used by the referred patients was by ambulances (73.9%). Around 48% of our population had GA of 33-36.6 weeks. 73% had emergency decision among which caesarean was 83%. Anaemia (34%), HDP (30.5%), GDM (14.2%) and hypothyroidism (17.7%) were medical co-morbidities necessitating referrals. There was 1 maternal death and 4 near miss mortality cases. Mean hospital stay in private sector referrals was 10.17 days and it was 7.62 days in government referrals.Conclusions: Timely referrals with detailed referral slips imparting information regarding treatment received at the referring hospital has helped in early and optimal intervention in the study.
Emotional intelligence of medical undergraduates: a cross sectional study
Authors: Ukey Ujwala U. , Sharma Sarita K. , Rathod Pragati , Patil Sonali S. , Choudhary Sanjeev M. , Narlawar Uday
Published: November 2019

Background: Emotional intelligence (EI) is defined as the ability to perceive, access and generate emotions. This in turn will assist thoughts to understand emotions and emotional meanings and thus reflectively regulate emotions so as to promote both better emotional and intellectual growth. EI is essential for a competent physician. The present study was conducted to know the EI of medical students.Methods: A cross sectional study was conducted at Government Medical College Nagpur among final year part 1 medical undergraduates. Data was collected with the help of pre tested, predesigned, self-administered proforma based on the “quick emotional intelligence self-assessment questionnaire”. Statistical analysis was done with epi info software and appropriate statistical tests were applied to prove the significance.Results: Of the total 197 study participants, 100 (50.76%) were female students and remaining 97 (49.24%) were male students. Mean score for EI was 102.16 With 95% confidence the population mean is between 99.6 and 105.Conclusions: Emotional intelligence for most of the study participants belonged to ‘consider strengthening’ category indicating good scores. Female medical undergraduates were more emotionally intelligent than male students.
Outbreak investigation of acid fly attack among residential students in a tertiary care centre in South India
Authors: Ramakrishnan Devraj , George Leyanna Susan , Jacob Arun , Lais Harsha , Rajeev Midhun , Panicker K. N. , Marwaha Vishal
Published: November 2019

Paederus dermatitis is the skin irritation resulting from contact with the haemolymph of certain rove beetles, a group that is comprised by the genus Paederus. In May 2018, there was an increase in the number of residential students reporting with burning skin lesions. In this context, an outbreak investigation was conducted. A team of public health specialists visited these residential buildings and premises. The inmates who were affected were interviewed and examined. Suspected insects were collected and entomologically evaluated by the Zoological Survey of India. On examination of the affected individuals, it was observed that the rashes were very much suggestive of acid fly toxin induced lesions. Inspection of the premises, revealed small heaps of dried leaves with moisture at two sites which could have served as a suitable environment for acid fly multiplication. Our study concluded that Paederus fuscipes as the causative agent. Top storeys of buildings, illuminated at night, facing potentially wet areas were considered to be the potential risk factor. Fly proofing of the building, cleaning the institution premises and chemical treatment was suggested as appropriate control measures.
Groundwater Potential Zones in Relation to Catchment Condition in Orenburg, Russia
Authors:   Samara National Research University, Moskovskoe Shosse 34А, Samara, Russia, 443086, Choudhary Komal ,   The Hong Kong Polytechnic University, Hong Kong,   University of Rennes 2, Rennes, France, Boori Mukesh ,   Samara National Research University, Moskovskoe Shosse 34А, Samara, Russia, 443086,   University of Rennes 2, Rennes, France,   American Sentinel University, Colorado, USA, Kupriyanov Alexander ,   Samara National Research University, Moskovskoe Shosse 34А, Samara, Russia, 443086,   Image Processing Systems Institute of RAS - Branch of the FSRC "Crystallography and Photonics" RAS, Molodogvardejskaya street 151, Samara, Russia, 443001
Published: November 2019

The main objective of this study was to detect groundwater availability for agriculture in the Orenburg, Russia. Remote sensing data (RS) and geographic information system (GIS) were used to locate potential zones for groundwater in Orenburg. Diverse maps such as a base map, geomorphological, geological structural, lithology, drainage, slope, land use/cover and groundwater potential zone were prepared using the satellite remote sensing data, ground truth data, and secondary data. ArcGIS software was utilized to manipulate these data sets. The groundwater availability of the study was classified into different classes such as very high, high, moderate, low and very low based on its hydro-geomorphological conditions. The land use/cover map was prepared using a digital classification technique with the limited ground truth for mapping irrigated areas in the Orenburg, Russia.
Solution for the problem of the parameters identification for autoregressions with multiple roots of characteristic equations
Authors:   Ulyanovsk State Technical University, Severny Venets, 32, Ulyanovsk, Russia, 432027, Andriyanov Nikita ,   Ulyanovsk Civil Aviation Institute, Mozhaiskogo, 8/8, Ulyanovsk, Russia, 432071, Sluzhivyi Maxim ,   Ulyanovsk State Technical University, Severny Venets, 32, Ulyanovsk, Russia, 432027
Published: November 2019

When describing a real image using a mathematical model, the problem of model parameters identification is of importance. In this case the identification itself is easier to perform when a particular type of model is known. In other words, if there is a number of models characterized by different properties, then if there is a correspondence with the type of suitable images, then the model to be used can be determined in advance. Therefore, in this paper, we do not consider the criteria for model selection, but perform the identification of parameters for autoregressive models, including those with multiple roots of characteristic equations. This is due to the fact that the effectiveness of identification is verified by the images generated by this model. However, even using this approach where the model is known, one must first determine the order of the model. In this regard, on the basis of YuleWalker equations, an algorithm for determining the order of the model is investigated, and the optimal parameters of the model are also found. In this case the proposed algorithm can be used when processing real images.
The Use of Scientific-Based Approach in ELT Class to Improve Students’ Achievement and Classroom Interaction
Authors: Haerazi Haerazi , May Vikasari Rully , Prayati Zukhairatunniswah
Published: November 2019

ABSTRACTThis study investigated the use of the scientific-based approach in the ELT class to solve students' learning problems. Those problems are students' difficulties to complete their learning tasks, lack of vocabularies to complete reading tasks, lack of grammatical competence, afraid of proposing questions, afraid of speaking, and difficulties to complete the listening tasks. These caused students to have low achievement and inactive classroom interaction. The study was aimed at improving students' achievement and classroom interaction of 8th-grade students of SMPN 4 Praya, Central Lombok, West Nusa Tenggara. This study was classroom action research. The procedure of actions included two steps, namely the reconnaissance and the action. The reconnaissance presented the students' learning problems and the action consisted of four stages, namely planning, implementing, evaluating, and reflecting. The research instruments of this study used observation sheets, a questionnaire, and a test. The collected data were analyzed quantitatively and qualitatively. The result of this study showed that the use of the scientific-based approach was able to improve students' achievement and classroom interaction. The students' average score was 82.76. Each student' score was higher than the minimum passing grade (70). Meanwhile, the interaction classroom was active. It was supported by significant changes. Those changes were that students become more cooperative, active, and optimistic to complete reading tasks, listening tasks, speaking activities, and writing assignments in the form of group discussion. Keywords: Scientific-Based Approach, Achievement, Classroom Interaction
Mapping of a transcription promoter located inside the priA gene of the Bacillus subtilis chromosome.
Authors: Hinc Krzysztof , Iwanicki Adam , Seror Simone , Obuchowski Michał
Published: November 2019

The genome sequence of the Gram-positive soil bacterium Bacillus subtilis was completed in 1997 (Kunst et al., 1998) and the results included the identification of a putative transcription unit encompassing the yloI to yloS genes. Within this region of the B. subtilis chromosome 11 putative open reading frames were found with a wide diversity of probable functions. In this work we have analyzed transcription in the region of the priA-cpgA genes and we have mapped a promoter which is located inside the priA gene and its activity directs transcription of the def-yloM genes. Moreover, this transcript can be extended at low level to the prpC-priK-cpgA genes. Analysis of the sequence in proximity of the transcription start site revealed a sequence suitable for the housekeeping sigma(A) subunit of RNA polymerase. Analysis of the beta-glactosidase activity of transcription fusions revealed that the identified promoter is active at low level and its activity is increased during late exponential phase of growth.
Tocopherol esters inhibit human glutathione S-transferase omega.
Authors: Sampayo-Reyes Adriana , Zakharyan Robert A
Published: November 2019

Human glutathione S-transferase omega 1-1 (hGSTO1-1) is a newly identified member of the glutathione S-transferase (GST) family of genes, which also contains alpha, mu, pi, sigma, theta, and zeta members. hGSTO1-1 catalyzes the reduction of arsenate, monomethylarsenate (MMA(V)), and dimethylarsenate (DMA(V)) and exhibits thioltransferase and dehydroascorbate reductase activities. Recent evidence has show that cytokine release inhibitory drugs, which specifically inhibit interleukin-1b (IL-1b), directly target hGSTO1-1. We found that (+)-alpha-tocopherol phosphate and (+)-alpha-tocopherol succinate inhibit hGSTO1-1 in a concentration-dependent manner with IC50 values of 2 microM and 4 microM, respectively. A Lineweaver-Burk plot demonstrated the uncompetitive nature of this inhibition. The molecular mechanism behind the inhibition of hGSTO1-1 by alpha-tocopherol esters (vitamin E) is important for understanding neurodegenerative diseases, which are also influenced by vitamin E.
Characterization of disulfide exchange between DsbA and HtrA proteins from Escherichia coli.
Authors: Skórko-Glonek Joanna , Sobiecka-Szkatuła Anna , Lipińska Barbara
Published: November 2019

DsbA is the major oxidase responsible for generation of disulfide bonds in proteins of E. coli envelope. In the present work we provided the first detailed characterization of disulfide exchange between DsbA and its natural substrate, HtrA protease. We demonstrated that HtrA oxidation relies on DsbA, both in vivo and in vitro. We followed the disulfide exchange between these proteins spectrofluorimetrically and found that DsbA oxidizes HtrA with a 1:1 stoichiometry. The calculated second-order apparent rate constant (kapp) of this reaction was 3.3x10(4)+/-0.6x10(4) M-1s-1. This value was significantly higher than the values obtained for nonfunctional disulfide exchanges between DsbA and DsbC or DsbD and it was comparable to the kapp values calculated for in vitro oxidation of certain non-natural DsbA substrates of eukaryotic origin.
Adenosine as a metabolic regulator of tissue function: production of adenosine by cytoplasmic 5'-nucleotidases.
Authors: Borowiec Agnieszka , Lechward Katarzyna , Tkacz-Stachowska Kinga , Składanowski Andrzej C
Published: November 2019

Adenosine is a product of complete dephosphorylation of adenine nucleotides which takes place in various compartments of the cell. This nucleoside is a significant signal molecule engaged in regulation of physiology and modulation of the function of numerous cell types (i.e. neurons, platelets, neutrophils, mast cells and smooth muscle cells in bronchi and vasculature, myocytes etc.). As part a of purinergic signaling system, adenosine mediates neurotransmission, conduction, secretion, vasodilation, proliferation and cell death. Most of the effects of adenosine help to protect cells and tissues during stress conditions such as ischemia or anoxia. Adenosine receptors and nucleoside transporters are targets for potential drugs in many pathophysiological situations. The adenosine-producing system in vertebrates involves a cascade dephosphorylating ATP and ending with 5'-nucleotidase (EC 3.1.3.5) localized either on the membrane or inside the cell. In this paper the cytoplasmic variants of 5'-nucleotidase are broadly characterized as well as their clinical relevance. The role of AMP-selective 5'-nucleotidase (cN-I) in the heart, skeletal muscle and brain is highlighted. cN-I action is crucial during ischemia and important for the efficacy of some nucleoside-based drugs and in the regulation of the substrate pool for nucleic acids synthesis. Inhibitors used in studying the roles of cytoplasmic and membrane-bound 5'-nucleotidases are also described.
Sequence-specific p53 gene damage by chloroacetaldehyde and its repair kinetics in Escherichia coli.
Authors: Kowalczyk Paweł , Cieśla Jarosław M , Saparbaev Murat , Laval Jacques , Tudek Barbara
Published: November 2019

Oxidative stress and certain environmental carcinogens, e.g. vinyl chloride and its metabolite chloroacetaldehyde (CAA), introduce promutagenic exocyclic adducts into DNA, among them 1,N(6)-ethenoadenine (epsilonA), 3,N(4)-ethenocytosine (epsilonC) and N(2),3-ethenoguanine (epsilonG). We studied sequence-specific interaction of the vinyl-chloride metabolite CAA with human p53 gene exons 5-8, using DNA Polymerase Fingerprint Analysis (DPFA), and identified sites of the highest sensitivity. CAA-induced DNA damage was more extensive in p53 regions which revealed secondary structure perturbations, and were localized in regions of mutation hot-spots. These perturbations inhibited DNA synthesis on undamaged template. We also studied the repair kinetics of CAA-induced DNA lesions in E. coli at nucleotide resolution level. A plasmid bearing full length cDNA of human p53 gene was modified in vitro with 360 mM CAA and transformed into E. coli DH5alpha strain, in which the adaptive response system had been induced by MMS treatment before the cells were made competent. Following transformation, plasmids were re-isolated from transformed cultures 35, 40, 50 min and 1-24 h after transformation, and further subjected to LM-PCR, using ANPG, MUG and Fpg glycosylases to identify the sites of DNA damage. In adaptive response-induced E. coli cells the majority of DNA lesions recognized by ANPG glycosylase were removed from plasmid DNA within 35 min, while MUG glycosylase excised base modifications only within 50 min, both in a sequence-dependent manner. In non-adapted cells resolution of plasmid topological forms was perturbed, suggesting inhibition of one or more bacterial topoisomerases by unrepaired epsilon-adducts. We also observed delayed consequences of DNA modification with CAA, manifesting as secondary DNA breaks, which appeared 3 h after transformation of damaged DNA into E. coli, and were repaired after 24 h.
Estudio de las cualidades de vuelo y manejo de una aeronave tipo planeador para instrucción
Authors: Castellanos Sanabria Yeinson Alfonso , Rodríguez Pirateque German Wedge
Published: November 2019

El objetivo de este artículo es hacer un estudio de las cualidades de vuelo y manejo de una aeronave tipo planeador para propósitos de instrucción. Para el desarrollo, un modelo dinámico es propuesto en pequeñas perturbaciones a fin de calcular el estado de equilibrio longitudinal en condiciones de vuelo subsónico. Con los datos del equilibrio longitudinal, fueron mostradas las ecuaciones de movimiento linealizadas para hallar los valores numéricos dimensionales y adimensionales de las derivadas de estabilidad y control aerodinámico a lo largo de los ejes longitudinal y lateral-direccional. Seguido, las funciones de transferencia características por perturbaciones y aceleraciones para la velocidad de mejor relación de planeo, son encontradas para calcular las respuestas de la aeronave en controles aerodinámicos. Finalmente, las respuestas de estabilidad estática y dinámica fueron obtenidas, y así, las cualidades de vuelo y manejo fueron analizadas de acuerdo a los requerimientos estandarizados. Los resultados obtenidos son presentados a partir de coeficientes aerodinámicos, gráficas de Matlab® (Paso, impulso, rampa, diagrama de Bode y lugar de raíces), modos de estabilidad, curva de pendiente de sustentación de Rudder, punto neutro de controles fijos y el margen máximo de estabilidad permitido. De esta forma, el cálculo de estabilidad, los factores de influencia y sus efectos en las cualidades de vuelo y manejo de una aeronave tipo planeador fueron demostradas.
Análisis espectral del diseño de una antena de radio afición
Authors: Olarte López Nancy Esperanza , Orrego Muñoz Carlos Antonio , Echeverry Vásquez Gustavo Emilio
Published: November 2019

La radio afición hoy en día es uno de los últimos recursos de comunicación en casos extremos. Su importancia en el ámbito mundial y número de seguidores día a día aumenta, contribuyendo a la formación de ligas de radioaficionados locales. Por otro lado, el conocer cómo diseñar tipos de antenas de radio afición también es de gran interés para no solo las comunidades que conforman las ligas, sino también se incrementa en el ámbito académico, particularmente en la práctica en un sistema de comunicación y su consideración en entornos de emergencias y desastres.

Esta investigación evidencia como se planteó el diseño de un prototipo de antena a partir de elementos de fácil acceso y posterior a su construcción, las pruebas de transmisión y recepción para su análisis espectral en un entorno local.

En primer lugar, brevemente se explica la importancia de la radio afición en las comunicaciones, luego se lleva a cabo una descripción sobre el tipo de antena escogida y los métodos empleados para su construcción, posteriormente se realiza un análisis comparativo de las diferentes pruebas llevadas a cabo bajo diferentes potencias de transmisión y distancias en un escenario local.
“You’ll never meet someone like me again”: Patty Jenkins’s Monster as Rogue Cinema
Authors: Wise Michelle D.
Published: November 2019

Film is a powerful medium that can influence audience’s perceptions, values and ideals. As filmmaking evolved into a serious art form, it became a powerful tool for telling stories that require us to re-examine our ideology. While it remains popular to adapt a literary novel or text for the screen, filmmakers have more freedom to pick and choose the stories they want to tell. This freedom allows filmmakers to explore narratives that might otherwise go unheard, which include stories that feature marginal figures, such as serial killers, as sympathetic protagonists, which is what director Patty Jenkins achieves in her 2003 film Monster. Charlize Theron’s transformation into and performance as Aileen Wuornos, and Jenkins’s presentation of the subject matter, make this film an example of rogue cinema. In addition, Aileen Wuornos is portrayed as a clear example of the rogue character. This character trope frequently defies social standards, suffers from past trauma, is psychologically complex, and is often exiled. As a prostitute and social outcast, Aileen Wuornos exists on the fringes of society and rejects the hegemonic power structure and later heteronormativity of society, which makes her a rogue figure. While there are several aspects to consider when analyzing Jenkins’s film, my intention is to argue that this film is an example of rogue cinema because of its content. In order to accomplish this task, I examine Theron’s bodily transformation and her performance as Wuornos. Furthermore, I look at how Jenkins handles the depiction of romantic love and gendered violence and argue that her treatment of this content renders this film rogue.
Heresy and Orthodoxy Now: The Zigzagging Paths of the Lawful
Authors: Zając Marta
Published: November 2019

In this article I consider a certain characteristic of our times as a “secular age,” namely, a series of complications in our understanding of transgression. Transgression implies the presence of some rules and laws which can be violated. As long as the rules and laws are perceived as right, as a way of protecting the values which would otherwise perish, transgression appears to be a wrong thing to do, a misdeed, a criminal act. Needless to say, the very conceptual structure makes sense only provided that the distinctions between right and wrong, good and evil, lawful and lawless are not arbitrary, which, in turn, depends on the presence of the concept of truth.

In the secular age, though, the concept of truth becomes not only difficult to handle, since it is incompatible with the modern frame of mind, but also assumes some derogatory connotations, up to the point when to insist on the distinction between (truly) right and (truly) wrong is in itself a wrong thing to do. That is the state of contemporary societies which G. K. Chesterton examines in his work Heretics. The effect of Chesterton’s reflections is a new map of right/wrong, good/evil, lawless/lawful permutations. After Chesterton, I comment on the character of a new heretic, one for whom transgression, understood as the attack on buried-for-long orthodoxy, is too easy a thing to do. To illustrate the mentioned changes of perspective, I refer to an exemplary criminal figure of the West, that is, the biblical serpent, and its criticism.
“A right kind of rogue”: Lisa McInerney’s The Glorious Heresies (2015) and The Blood Miracles (2017)
Authors: Ostalska Katarzyna
Published: November 2019

The following article analyzes two novels, published recently by a new, powerful voice in Irish fiction, Lisa McInerney: her critically acclaimed debut The Glorious Heresies (2015) and its continuation The Blood Miracles (2017). McInerney’s works can be distinguished by the crucial qualities of the Irish Noir genre. The Glorious Heresies and The Blood Miracles are presented from the perspective of a middle-aged “right-rogue” heroine, Maureen Phelan. Due to her violent and law-breaking revenge activities, such as burning down the institutions signifying Irishwomen’s oppression (i.e. the church and a former brothel) and committing an involuntary murder, Maureen remains a multi-dimensional rogue character, not easily definable or even identifiable. The focal character’s narrative operates around the abuse of unmarried, young Irish mothers of previous generations who were coerced to give up their “illegitimate” children for adoption and led a solitary existence away from them. The article examines other “options” available to “fallen women” (especially unmarried mothers) in Ireland in the mid-twenty century, such as the Magdalene Laundries based on female slave work, and sending children born “out of wedlock” abroad, or to Mother and Baby Homes with high death-rates. Maureen’s rage and her need for retaliation speak for Irish women who, due to the Church-governed moral code, were held in contempt both by their families and religious authorities. As a representative of the Irish noir genre, McInerney’s fiction depicts the narrative of “rogue” Irish motherhood in a non-apologetic, ironic, irreverent and vengeful manner.
PETSCII – A Character Set and a Creative Platform
Authors: Reunanen Markku , Heikkinen Tero , Carlsson Anders
Published: November 2019

PETSCII is the built-in character set used on 8-bit Commodore computers, such as the PET, C-64 and Plus/4. The character set and the BASIC environment provided an entry point to rudimentary graphic editing for a generation of hobbyists. Over the years PETSCII has been used for a variety of creative purposes: for example games, demos, telecommunications, videos, books and fine art have been created using the graphical symbols. Through the analysis of existing art works and our own hands-on project – a graphics editor – we dig deeper into the specific properties of the character set. In this article we show how the fixed symbols set the frame for what is possible and how, on the other hand, they provide grounds for creative experimentation, display of skill and recognizable styles.
Institusi Pesantren Sebagai Local-Genius Mampu Bertahan Menghadapi Ekspansi Modernisasi Pendidikan
Authors: Bahri Samsul
Published: November 2019

Tulisan ini mengkaji Institusi Pesantren sebagai kearifan-lokal mampu bertahan menghadapi ekspansi modernisasi pendidikan. Metode yang digunakan adalah deskriptif-analitis dengan pendekatan sosiologis-hostoris. Studi ini menyimpulkan bahwa pesantren sebagai kearifan-lokal mempunyai daya tahan yang kuat dalam menghadapi ekspansi modernisasi pendidikan, hal ini dikarenakan institusi pesantren memiliki modal tradisi yang dipegangi, proses pendidikan, serta sesuai dengan teori sosial fungsional dalam sebuah organisasi. (This paper examines the Islamic Boarding School Institution as local wisdom able to withstand the expansion of education modernization. The method used is descriptive-analytical with a sociological-hostoris approach. This study concludes that pesantren as local wisdom has strong resilience in facing the expansion of education modernization, this is because pesantren institutions have traditional capital that is held, education process, and in accordance with functional social theory in an organization.)
Harmonisasi Pengaturan Persaingan Pasar Tradisional Dengan Toko Modern Di Kabupaten Sukoharjo
Authors: Utami Septiana Putri
Published: November 2019

Penelitian ini bertujuan untuk mengetahui regulasi terhadap pengaturan persaingan pasar tradisional dengan toko modern di kabupaten Sukoharjo; pelaksanaan regulasi terkait pengaturan persaingan pasar tradisional dengan toko modern di kabupaten Sukoharjo; menciptakan harmonisasi pengaturan pasar tradisional dengan toko modern di kabupaten Sukoharjo. Penelitian ini menggunakan metode pendekatan yurudis sosiologis dengan populasi penelitian berupa 26 pasar tradisional di kabupaten Sukoharjo. teknik pengambilan sampel yang digunakan adalah purposive sampling dengan menggunakan 3 pasar tradisional dengan sub populasi yang berdekatan dengan toko modern.Hasil penelitian ini adalah pengaturan persaingan pasar tradisional dan toko modern di kabupaten Sukoharjo diatur pada Perda No. 17 Tahun 2017 tentang penataan dan pembinaan pasar rakyat, pusat perbelanjaan dan toko swalayan; terdapat pelanggaran pelaksanaan regulasi yang dilakukan oleh pengusaha toko modern dalam hal manipulasi izin toko kelontong yang beroperasi dengan konsep toko modern; guna menciptakan harmonisasi pengaturan pasar tradisional dan toko modern diperlukan tindakan prefentif dan represif.(This study aims to determine the regulation of traditional market competition arrangements with modern stores in Sukoharjo district; implementing regulations related to the traditional market competition arrangements with modern stores in Sukoharjo district; creating harmonization of traditional market arrangements with modern stores in Sukoharjo district. This study used a method of sociological jurudical approach with the study population of 26 traditional markets in Sukoharjo district. The sampling technique used was purposive sampling using 3 traditional markets with sub-populations adjacent to modern stores.The results of this study are traditional market competition arrangements and modern stores in Sukoharjo district regulated in Local Regulation (Perda) No. 17 year 2017 about structuring and coaching public markets, shopping centers and convenience stores; there are violations in the implementation of regulations carried out by modern store entrepreneurs in term of manipulation of grocery store licenses operating with the concept of a modern store; in order to create harmonization of traditional market arrangements and modern stores, it requires preventive and repressive actions.)
PENINGKATAN PENGALAMAN KEUANGAN REMAJA UNTUK LITERASI KEUANGAN SYARIAH YANG LEBIH BAIK
Authors: Triani Ani , Mulyadi Hari
Published: November 2019

Indeks literasi keuangan syariah yang rendah dilaporkan Otoritas Jasa Keuangan (OJK), yaitu sebesar 8,1%. Artinya, 8 dari 100 penduduk Indonesia dapat dikatakan melek keuangan syariah. Sangat minim bila dibandingkan dengan 222 juta atau lebih dari 87% penduduk Muslim di Indonesia. Urgensi literasi keuangan syariah muncul manakala potensi yang besar nampak dari peningkatan aset, variasi produk,  serta  regulasi  yang  semakin  komprehensif.  Sederet  program  diluncurkan  untuk  memenuhi tuntutan peningkatan literasi keuangan syariah, tak terkecuali program pendidikan dikalangan muda. Namun, banyak studi menunjukkan program pendidikan yang dijalankan kerap berujung pada kegagalan. Identifikasi mengarah kepada kurangnya penelusuran pada akar pengalaman keuangan. Studi  dimaksudkan  untuk  mengkolaborasikan  gagasan  yang  dapat  berperan  untuk  meningkatkan literasi keuangan syariah dikalangan remaja. Pengalaman dengan uang dan pengajaran orangtua menjadi modalitas yang diharapkan mampu untuk meningkatkannya. Metode kualitatif dipilih dalam rangka membangun pemahaman awal dan mengkonstruksikannya kembali. Hasil akhir dari penulisan berupa kontribusi pemikiran terhadap perspektif pengalaman keuangan remaja yang diharapkan mampu meningkatkan literasi keuangan syariah. Hal ini turut menyadarkan remaja bertindak rasional dalam menyikapi  uang  sesuai  ajaran  Islam.  Kebenaran  ajaran  Islam  mestinya  tidak  hanya  bermakna kesuksesan akhirat melainkan mampu menjadi pedoman bagi kesuksesan dunia.
EFFICIENCY PERFORMANCE ANALYSIS OF PANIN DUBAI SYARIAH BANK IN COLLECTING AND DISTRIBUTING THIRD PARTY FUNDS BEFORE AND AFTER MERGER
Authors: Supriyono Supriyono , Rodoni Ahmad , Suparno Yacop , Hermadi Hermadi , Nafisah Hilyatun
Published: November 2019

In this study, the researcher would make Panin Dubai Syariah Bank was the object of research on Islamic banks that carry out mergers and acquisitions. This research by using quarterly financial reports to determine the level of efficiency of the Panin Dubai Syariah Bank to be analyzed using the Data Envelopment Analysis (DEA) method. The researcher was used the annual report to find out the extent the Panin Dubai Syariah Bank carries out its Shariah values and objectives to be analyzed based on the Maqashid Index Sharia. The frontier approach can be divided into parametric approaches and non-parametric approaches. The parametric  approach  takes  measurements  using  stochastic  econometrics  and  seeks  to  eliminate interference from the effects of inefficiency. While the non-parametric approach with linear programs ( non-parametric linear programming approach ) performs non-parametric measurements using an approach is not stochastic and tends to combine the interference into inefficiency. This is based on the discovery and observation of the population and evaluates efficiency relative to the units observed. In the non- parametric method, the approaches that can be used are Data Envelopment Analysis (DEA) and Free Disposal Hull (FDH). The results of the measurement of Bank Panin Dubai Syariah using DEA indicate that the decision to merge carried out by Panin Syariah Bank with Dubai Islamic Bank was the right decision because, with the merger, Panin Dubai Syariah Bank could produce almost perfect efficiency value of 99% in the year 2015. With doing the merger, Bank Panin Dubai Syariah can minimize the inefficiencies that occur in the input variable so that it can maximize the efficiency that occurs in the output variable