bluuebunny/crossref_metadata_2025 huggingface dataset:
Identification of Trichophyton benhamiae by MALDI-TOF Mass Spectrometry. First report in Peru
Authors: Alvarado Luis , Quiroz-Reyna Maritza , Quiroz-Chunga Giancarlo , Castillo-Aguilar William , Quedo-Salazar Flor
Published: May 2024

is an emerging zoophilic dermatophyte that mainly infects skin and scalp and has been reported in Asia, America and Europe. It has two phenotypic variants: one with white colonies and the other with yellow colonies. Morphological identification of is not sufficient and can be confused with or . Genomic or proteomic analysis is required to establish a definitive identification. We present three dermatophyte strains obtained from the skin, nails and scalp of human infections in which macroscopic and microscopic examinations were not sufficient to identify the species. The final identification of was performed using MALDI-TOF mass spectrometry. This is the first report of in Peru.
Implementation of team based learning for MBBS students – An innovative teaching learning method in medical education
Authors: Arumugam Balaji , Shoraf P  , Sanjana L  , Mahendran C  , Ramesh Thirumagal , Sakthipriyan S
Published: May 2024

Team-Based Learning (TBL) is an educational approach that enhances student engagement through individual assessments and collaborative group work. It is an effective and structured form of small group learning adaptable to large classroom settings. TBL ensures student accountability through various stages, including pre-class preparation, readiness assurance tests, problem-solving exercises, and immediate feedback.

This study aims to implement and assess the efficacy of the TBL strategy among MBBS students in a large group teaching environment.

The pilot study adopted a TBL approach, involving steps such as pre-class preparation with PDF materials and a WhatsApp video guide issued a week prior, individual and team readiness assurance tests (iRAT and tRAT) conducted via Google Forms and hard copy MCQs, clarification sessions on MCQs and relevant medical topics, and collaborative learning through case scenarios related to Type 2 diabetes. Discussions and conclusions were facilitated by the faculty, followed by immediate and scheduled feedback using Google Forms. Statistical analysis was performed using an unpaired t-test to compare iRAT and tRAT scores.

The study gathered 133 responses from the first batch and 140 from the second batch of first year MBBS students. The analysis revealed significant improvements in scores from iRAT to tRAT, indicating the effectiveness of TBL in enhancing student learning outcomes. Feedback from the students showed high levels of engagement and interest in the learning process, with over 98% in both batches finding the TBL approach interesting and interactive.

The findings suggest that TBL is a valuable and effective educational strategy that improves learning outcomes and fosters collaborative learning among students.
Stocktaking of Private Finance Mobilization at the IDB Group
Authors: Cuestas Ernesto , Andrade Sakaguchi Sumiko , Vargas Lucero , Vera Priscila , Miranda Laura , King Julie , Wong Melisa , Carbajo José , Lankes Hans-Peter , Pérez Yarahuán Gabriela , Linares Ana María
Published: May 2024

In the past two decades, as public sector finance has proven insufficient to meet global development needs, private finance mobilization (PFM) has emerged as a key approach for development financing in Latin America and the Caribbean (LAC). Recognizing that relying only on profits, additional capital contributions, and grant resources from the donor community or public sector entities is insufficient to fund the growing development needs; multilateral development banks (MDBs) have looked at PFM as one of the ways to increase available development financing. This stocktaking reviews the experience of the Inter-American Development Bank Group (IDBG) using PFM as a tool to obtain additional private sector resources for the operations it finances. OVE analyzed PFM at two levels: strategic and operational. The strategic level covers what the IDBG intended to achieve with PFM (objectives) and the approach selected. The operational level covers how the PFM approach was implemented and what has been accomplished to date. Given their different business models, PFM has evolved differently at the IDB and IDB Invest. OVE, therefore, examined them separately.
The ambiguous beginning of life and the binary pattern – a phenomenological analysis of intersexual experience
Authors: Alichniewicz Anna
Published: May 2024

In my paper, I attempt a phenomenological analysis of the lived experience of intersexuality, which I view from the perspective of the problem of indeterminacy concerning the horizon of the givenness of homeworld founded on the broader basis of the pre-givenness of lifeworld. These horizons define the structure of the sedimentation of subjective experience, as well as the layers of cultural meanings sedimented in the lifeworld. The sedimented layers of self-experience and of the shared lifeworld function as a sphere of indeterminacy, that is the horizons of constituted phenomena. In this sense all intentional acts have the nature of horizontal indeterminacy, the layers of which are revealed in the genetic question (Rückfrage) directed toward them. Horizontal indeterminacy also accounts for the distinction between homeworld and alienworld, which appears as something unobvious and unexpected against the obviousness of the homeworld, at the same time thematizing the latter. One of the elements of the sedimented conceptual system, functioning as the horizon of indeterminacy of both self-experience and the pre-reflective life-world, is the notion of human corporeality as given in the binary sexuality/gender. A unique opportunity for phenomenological insight into the constitution of the phenomenon of sex/gender is provided by Hida Viloria's lived experience of intersexuality. Her lived body, originally experienced pre-reflectively as a transparent medium and a perfectly handy tool of undisturbed intentionality, unproblematized also in the sexual activities, gradually undergoes alienation under the objectifying gaze determined by the binary pattern of sexuality. Becoming an alienated object, her body loses its transparency. Viloria begins to experience her corporeality and identity in a way determined by the sedimented "ideology" of sex and gender, trying on the "constructs" of masculine and feminine identities, eventually overcoming alienation and, in a process of secondary self-identification, reclaiming her lived body in its intersexuality and her identity in its non-binary gender fluidity.
Aestheticism and the Others: The Social Dimension of Nietzsche's Views on Self-Fashioning
Authors: Čukljević Filip
Published: May 2024

In this article, I shall explore the social dimension of Friedrich Nietzsche's views on self-fashioning, focusing on the interpretation offered by Alexander Nehamas. First, I shall briefly present Nehamas's understanding of Nietzsche's views on self-fashioning and the overall significance of their social aspects. Then I shall investigate the necessity of the audience to assess one's attempt at self-fashioning. Furthermore, I shall explore how one's pursuit of self-fashioning is influenced by and influences other similar efforts. Finally, the article will reveal the role of contest in the phenomenon of influence.
Európai Unió – a beteljesületlen remény?
Authors: Csaba László
Published: May 2024

After two decades of EU membership, a majority of the Hungarian public still supports membership. However, reflecting intense governmental influencing in terms of communication and policies alike, the previously negligible euroskepticism has benn gaining substantial ground. Following a different path from what ‘Brussels’ aims at, has become part and parcel of good manners nowadays. The round anniversary of Hungary’s EU accession allows for a strategic rethinking of pluses and minuses of the road taken. Finally, I contemplate where the line of regular confrontation with the Union may lead us.
Emlékképek Magyarország uniós tagságának első éveiből
Authors: Iván Gábor
Published: May 2024

In the period between Hungary’s accession to the European Union in May 2004 and the first Hungarian presidency of the EU in 2011, Hungary became a member state with all the experiences necessary to enjoy the benefits of EU membership. During these seven years, Hungary became part of the renewal of the EU Treaties, adopted a strategy about its EU policy, went through the baptism of fire of the debate on multiannual financial frameworks, became part of the Schengen area, successfully fulfilled its tasks during the presidency, and played a pivotal role in concluding Croatia’s EU accession negotiations. The commitment, the belief in the common interests of the Union and Hungary, which was the driving force of the Hungarian accession negotiations, persisted. The author recalls the events which were of decisive importance in the first seven years of Hungary’s EU membership. The recollection is based on the memories of his personal contribution.
EL RECURSO RETÓRICO DEL “LUGAR COMÚN” (κοινὸς τόπος) EN BASILIO DE CESAREA
Authors: Valdés García María Alejandra
Published: May 2024

Este escrito aborda el recurso del “lugar común” con el objetivo de demostrar la factura retórica utilizada por Basilio de Cesarea en dos homilías sobre la avaricia. Procedemos en su desarrollo a través de tres tiempos: 1) Desambiguación de “lugar común”, 2) La teoría retórica griega y 3) El “lugar común” en Basilio de Cesarea. A través de estos apartados, se explica el recurso en la teoría retórica griega y se comprueba el dominio de la estructura y su argumentación por parte de Basilio. Para ello, se ejemplifica la elaboración en “Homilia in illud: Destruam horrea mea et maiora aedificabo” (HDestr. 7) y “Homilia in divites” (HDiv. 6). El “lugar común” es, entre los ejercicios preparatorios, uno de los más complejos en cuanto al discernimiento de los lugares de argumentación, por ello nos basamos en la teoría retórica de los Progymnásmata, que facilita la comprensión por su sencillez y agiliza la comparación de las estructuras tanto en el pensamiento profano como en el cristiano. A su vez, los rétores antiguos nos comprueban que el “lugar común” equivale a una amplificación. Los cuadros comparativos resumen, en una visión de conjunto, los resultados que certifican que, aunque cada homilía es de distinta factura, prevalecen los esquemas de los rétores Teón y Pseudo Hermógenes, a la vez que evidencian la originalidad del orador. No existen estudios retóricos de este recurso sobre nuestro autor, por lo que esperamos que esta aportación dé pie a escritos semejantes.
EL DISCERNIMIENTO DE LAS VISIONES SEGÚN EVAGRIO PÓNTICO
Authors: Singh Mesconi Carlos Marcelo
Published: May 2024

En este estudio hemos de analizar el sentido de las visiones según Evagrio Póntico y de qué manera se pueden discernir para determinar fundamentalmente si provienen de Dios o del enemigo. Para tal fin, partiremos deuna clave contextual sobre la gnoseología evagriana; en efecto, las “visiones” corresponden a una cierta forma de conocer y comprender la realidad. Luego analizaremos el deseo de la visio Dei. Seguidamente abordaremos las otras visiones y su etiología. Se propondrá una “terapéutica”, considerando que el discernir se abre a una acción curativa. Notaremos cómo el autor indaga en la misma raíz del problema: la avidez por ver sensiblemente la divinidad. Asimismo, se describirán otras causas como la vanagloria y la presunción. El título del presente estudio nos permite señalar los términos fundamentales: el “discernimiento” (διάκρισις) y las visiones, para las cuales encontramos diversos conceptos técnicos: ὅρασις, ὀπτασία, ὄψις, ὅραμα, entre otros.
Pulses in Uttarakhand: Has Their Potential Been Tapped Enough to Attain Food and Nutritional Security?
Authors: Srivastava Shefali , Bisht Anju , Baurai Rupanjali , Srivastava Sarita
Published: May 2024

Background: Malnutrition is a global health crisis and Uttarakhand state is no exception. Besides the implementation of various government schemes for eradication of undernutrition is at very slow pace calls for analyzing the present situation and future prospects of food crops. In this regard, Uttarakhand a hilly state with many agricultural constraints needs special attention. Pulses known for rich protein and micronutrient content can serve as an excellent source for mitigating protein deficiency and attaining food and nutrition security. Various pulses in different cropping pattern are being grown in the state. The current study aims at exploring the dynamics, diversification and decomposition of pulses in Uttarakhand and their role in providing food and nutritional security. Methods: Secondary data related to area under pulses, production and yield were taken from official website of Agriculture department, Government of Uttarakhand. The data gaps were filled through linear interpolation. Production of total pulses was linearly extrapolated to estimate pulses production for 2035-36. Growth and instability, diversification and decomposition of pulses were analyzed. The Food and Nutritional security statistics were taken from directorate of Economics and Statistics, Government of Uttarakhand and explored in relation to pulses. Result: It was found that the state is faring well in production of pulses as an increase in absolute area, production, yield and proportion of pulses in gross sown area was observed. High pulse diversification was seen. However, a decline in all major pulse-based cropping systems was seen. Moreover, in the state, where 31% of the population lacks adequate protein intake, there is a pressing need to enhance the availability, accessibility and absorption of protein-rich pulses, particularly for vegetarians. Additionally, it is essential to reevaluate the state’s food and nutrition security status in alignment with the updated guidelines from ICMR-NIN in 2020.
The Influence of Deep Rolling Process on Fatigue Durability for Vehicle Tie-Rod Component
Authors: Hasanoğlu Emre Azim , Dayı Sinan , Sayı Abdulmecit Harun
Published: May 2024

In the automotive industry, most of the components are consistently subjected to the dynamic loading due to the randomly observed situations from road inputs and periodic vibration from IC engine working during the operation. Such loadings cause the durability problem which may result in failure or cracking at stresses that are well below the yield strength of the material. Therefore, along with the development of new processing techniques, different surface treatment processes are applied to enhance the fatigue behavior of components. Being one of the mechanical surface treatment methods, deep rolling is an efficient way for improvement of fatigue performance by strengthening the critical section and providing compressive type of residual stresses. In this paper, the effect of the deep rolling process on fatigue behavior of steel stud in tie-rod used as steering system component was investigated. Force-Number of cycles curves (F-N graph) for the fatigue test have been obtained from the tests. Evaluation of the fatigue endurance limits of the stud at un-rolled condition and rolled conditions at three different loads were performed. Test data was analyzed with a regression line to account for the scatter using probability density functions. The results indicate a significant enhancement in the endurance limit following the implementation of the rolling process, as compared to the unrolled state. Furthermore, it was observed that the endurance limit proportionally increased in line with the rolling load. These findings underscore the crucial role of the deep rolling process in determining the optimal rolling load for the specific stud design and material conditions.
Effect of Auditor Ethics, Audit Experience, and Auditor Motivation on Internal Audit Quality
Authors: Mahmud Muhammad Daud Bin , Quilim Cici Aryansi , Hasan Lisa
Published: May 2024

The purpose of this study is to investigate how auditor motivation, audit experience, and ethics relate to the quality of audit result as evaluated by internal supervisors in local government. This study is driven by the perception that the government's internal oversight system lacks professionalism due to its poor performance in identifying state financial management fraud. Using Partial Least Square - Structural Equation Modeling (PLS-SEM) with SmartPLS 4 to assess the research model following the distribution of a questionnaire to thirty auditors designated to examine state financial management within the Central Halmahera Regency Government's jurisdiction. The study's findings demonstrate the significance of auditor ethics, audit experience, and motivation in completing audit duties in producing high-quality audit outcomes
Penerapan Penerapan PSAK No. 102 di BMT UGT Nusantara Cabang Pamekasan
Authors: Ira Farlizanty Tri Rahadi Ira Farlizanty Tri Rahadi , Fadllan
Published: May 2024

PSAK No. 102 covers recognition and measurement, presentation and disclosure in murabahah financing in Sharia Cooperatives and Sharia Financial Institutions to sell or buy, as well as the implementation of murabahah transactions for cooperatives or Sharia financial institutions. Until now, many people are interested in murabaha financing. The number of enthusiasts who use murabaha financing, then automatically in murabaha financing will often be recorded transactions. The purpose of this study is to determine how the application of PSAK 102 at BMT UGT Nusantara Pamekasan Branch. By using qualitative methods with a case study approach and type of field research. Sources of data obtained through primary data and secondary data, which primary data to the deputy branch head, AOAP and teller, as well as secondary data in the form of financial reports from BMT UGT Nusantara Pamekasan Regency Branch. Based on the results of his research, in BMT UGT Nusantara Pamekasan Branch is in accordance with PSAK 102, but there are some points that are not yet appropriate and still need to be refined by BMT. Such as BMT does not provide murabahah without orders, BMT does not provide collateral other than motorcycle BPKB, BMT does not measure inventory at cost, BMT does not have significant risks associated with inventory ownership and BMT does not provide penalties.
Uma revisão narrativa das percepções e concepções de estudantes brasileiros e portugueses sobre as mudanças climáticas
Authors: Couto Victor Hugo , Gonçalves Pedro Wagner , Sermeus Jan
Published: May 2024

Introdução e Objetivo. Esta revisão narrativa busca analisar o entendimento de estudantes brasileiros e portugueses acerca de mudanças climáticas a partir de uma síntese e discussão da literatura. Metodologia. Foi realizado um mapeamento de concepções errôneas por intermédio de revisão bibliográfica de trabalhos que focalizem o público-alvo dos anos finais do ensino básico e médio aos anos iniciais da universidade (14 a 21 anos aproximadamente). Resultados. Observou-se um compartilhamento de praticamente todas as concepções errôneas, à exceção de duas que foram exclusivas de cada um dos países. Foram assim levantadas hipóteses sobre: (a) o estágio atual da educação ambiental, (b) a incidência de concepções errôneas, (c) currículos nacionais e (d) a prática docente. Conclusão. No geral, encontraram-se muito mais semelhanças do que diferenças nas dificuldades encontradas por estudantes (e professores), que fornecem uma base para discussões interessantes para os dois países dada sua história tão interligada, mas de realidades tão distintas.
Análise e reflexão acerca da abordagem curricular dos conhecimentos geocientíficos e das mudanças climáticas no ensino fundamental (anos finais)
Authors: Farhat Junior Marcos Zacarias , Amaral Wagner da Silva , Coltri Priscila Pereira
Published: May 2024

Introdução e Objetivo. Este artigo examina as proposições dos Parâmetros Curriculares Nacionais (PCN) para o Ensino Fundamental e as deliberações preconizadas pela Base Nacional Comum Curricular (BNCC) para as instituições e redes de ensino brasileiras. Metodologia. Empregou-se a metodologia de análise de conteúdo e de revisão da literatura correlata, sob perspectiva holística, para avaliar de que forma os temas sobre Ciências da Terra e sobre mudanças do clima são apresentados, abordados e distribuídos nos componentes curriculares. Resultados. Após a homologação da BNCC, há uma concentração de conceitos e elucidações de processos e fenômenos terrestres na disciplina Ciências, ao passo que a disciplina Geografia se incumbe de correlacionar os conceitos à problemática socioambiental e econômica. Verifica-se a grande dispersão e a descontextualização das temáticas geocientíficas, que dificultam a compreensão sistêmica e holística do Sistema Terra e da problemática socioambiental atual. Conclusão. Em concordância com a literatura que sustenta a argumentação deste trabalho, vislumbramos as práticas pedagógicas interdisciplinares e/ou o advento de um componente curricular específico de Ciências da Terra como alternativa para sistematizar e contextualizar as temáticas geocientíficas.
Steady undermining of the UK National Health Service underlies industrial action by doctors and other staff
Authors: Puntis John WL
Published: May 2024

Erosion of standard of healthcare in the United Kingdom underlies the industrial action taken recently by staff in the publicly provided National Health Service. Underfunding and understaffing, largely as a consequence of neoliberal government “austerity” policies implemented following the 2007-08 banking crisis, together with lack of long-term planning and a drive towards outsourcing, have led to a deterioration in the quality of services. Reduction in bed numbers and neglect of community and social support have compounded problems by making it more difficult both to admit and to discharge patients in a timely fashion. Access to services has been compromised with negative consequences for the sick. Reduction of doctors’ real wages together with stress at work, moral injury caused by feelings of not being able to do the best for patients, burnout from the Covid-19 pandemic and uncertainty about the future have led to the longest ever strike action by junior doctors in England.
DEVELOPMENT OF DIGITAL SUBSTATION CONSTRUCTION TECHNOLOGIES.
Authors: Drubetska Tetiana , Zemskyi Denys , Shmelova V. , Artemchuk Viktor
Published: May 2024

The development of technologies for the construction of digital substations is discussed in the article. The construction of a digital substation provides the following advantages. There are increasing the reliability of the equipment's functioning; reducing the costs of operating the equipment; increasing the efficiency of the use of the main equipment.
Modern information technologies and innovative approaches to solving the tasks of automation and management of power facilities, which allow creating new type substations, have been studied.
The principle of interaction of digital substation equipment is given.
The differences between digital substations and analog substations are shown. The principle of operation of classical and digital substations is presented.
The international experience of implementing digital substations is described.
Digital substation is one of the basic technologies of Smart Grid. The basis of the construction of a digital substation is the replacement of numerous connections made by wires for the exchange of traditional analog and discrete signals with a unified exchange of digital messages, which provide the possibility of distributed implementation of the functions of the substation automation system and full functional compatibility of intelligent electronic devices of various manufacturers.
The concept of "Intelligent" transformer is disclosed.
A step-by-step transition to a digital substation is presented.
Armenia: Abandonment of the Trinity of the Nation and Search for New Guidelines
Authors: Krylov A.
Published: May 2024

The formula of the trinity of the Armenian nation was declared in September 1999 at the first All-Armenian Congress “Armenia–Diaspora”. Subsequently, the leaders of Armenia constantly emphasized their commitment to the trinity of Armenia – Artsakh – Diaspora, and a fair solution to the Armenian issue (Armenia within the “Wilson borders” or more extensive). After the defeat in the Second Karabakh War, the Armenian government abandoned the formula of the trinity of the nation. N.Pashinyan declared his commitment exclusively to the state interests of the Republic of Armenia within the borders of the former Armenian SSR. The Armenian opposition, the church and the Diaspora assessed N.Pashinyan’s policy as a national betrayal and remained committed to the trinity of the nation. The inability of the opposition to develop a new pan-Armenian strategy and remove N.Pashinyan from power is explained both by its fragmentation and by the disoriented and apathetic state of society. The constitutional reform planned by N.Pashinyan will make it possible to legislate the Armenian state’s refusal of the trinity formula and the principles contained in the Declaration of Independence and the Constitution of Armenia.
The EAEU in Global Integration Processes
Authors: Krivogouz M. , Fesenko D.
Published: May 2024

The authors analyze the transformation of the international economic integration processes, influenced by the changes in the global world order during the last 25 years. Special attention is payed to the structures with Russian partnership, in particular – the EAEU. The conclusion of a variety of modern forms of international economic cooperation and serious challenges for the EAEU is made.
MODELING AND SIMULATION OF INDUSTRIAL PROCESSES = Modelado y simulación de procesos industriales
Authors: Caparros-Mancera Julio Jose , Rodríguez Cesar Antonio , Rodríguez-Pérez Ángel Mariano , Hernández-Torres Jose Antonio
Published: May 2024

Este artículo presenta una metodología didáctica aplicada a los estudios de ingeniería. A partir del uso de herramientas digitales se desarrolla una metodología para modelar y simular un proceso de fabricación industrial. La metodología comienza con el análisis del proceso de fabricación, por lo que los estudiantes realizan una aproximación analítica al modelado del sistema productivo analizado. A continuación, se utiliza una herramienta digital para modelar dicho sistema en base a los parámetros previamente analizados. Con la simulación del modelo, los estudiantes de ingeniería analizan los resultados de tiempos y costes específicos de cada proceso y producto. En base a estos se presentan propuestas de mejora para optimizar el proceso que se modela y simula nuevamente para comprobar la eficiencia y beneficio de las mejoras propuestas en el proceso. Con esta metodología, los estudiantes de ingeniería se introducen en un contexto escalable de la industria real para realizar mejoras seguras, al mismo tiempo que desarrollan habilidades en ingeniería de procesos y herramientas digitales.AbstractThis paper presents a didactic methodology applied to engineering studies. From the use of digital tools, a methodology is developed to model and simulate an industrial manufacturing process. The methodology begins with the analysis of the manufacturing process, so the students carry out an analytical approach to the modeling of the analyzed production system. Next, a digital tool is used to model said system based on the previously analyzed parameters. With the simulation of the model, engineering students analyze the results of specific times and costs of each process and product. Based on these, improvement proposal are presented to optimize the process that are modelling and simulated again to check the efficiency and benefit of the proposed improvements in the process. With this methodology, engineering students are introduced to a scalable context of real industry for safe improvements, while developing skills in digital tools and processes engineering.
Discurso grupal basado en narrativas generadas por inteligencia artificial como metodología activa en la enseñanza en arquitectura = Group discourse based on narratives generated by artificial intelligence as an active methodology in teaching students in construction
Authors: Navas-Martín Miguel Ángel , Cuerdo-Vilches Teresa
Published: May 2024

La educación está experimentando una renovación pedagógica. Para lograr este cambio, se requieren nuevas metodologías de enseñanza que involucren a los estudiantes en el proceso. Las metodologías activas son apropiadas para esta revolución educativa. En este estudio, se propone una adaptación metodológica que utiliza grupos participativos y narrativas generadas por inteligencia artificial a través de ChatGPT como método para fomentar una comunicación fluida entre el profesor y los estudiantes, así como entre los propios estudiantes, promoviendo su participación en el proceso de aprendizaje. A través de la generación de tres historias ficticias que abordan los efectos del cambio climático en viviendas, se facilita la construcción de elementos discursivos en grupo. El debate entre los alumnos conduce a mejoras arquitectónicas, constructivas y técnicas que podrían implementarse en los casos presentados en las narrativas.AbstractEducation is undergoing a pedagogical renewal. To achieve this change, new teaching methodologies that involve students in the process are required. Active methodologies are appropriate for this educational revolution. This study proposes a methodological adaptation that uses participatory groups and narratives generated by artificial intelligence through ChatGPT as a method to foster fluid communication between the teacher and the students, as well as among the students themselves, promoting their participation in the learning process. Through the generation of three fictional stories that address the effects of climate change on housing, the construction of discursive elements in groups is facilitated. The discussion among the students leads to architectural, constructive and technical improvements that could be implemented in the cases presented in the narratives.
Producción de biocombustibles a partir de melaza de caña de azúcar usando Serratia marcescens
Authors: Cisneros de la Cueva Sergio , Álvarez Guzman Cecilia Lizeth , Salmerón Ivan , Pérez Vega Samuel Bernardo , Santiago Adame Rubén
Published: May 2024

En este estudio, diferentes concentraciones de azúcares totales de melaza de caña de azúcar de 0, 15, 30, 45 y 60 g/L fueron evaluadas para la producción de hidrógeno, etanol y 3-metil-1-butanol mediante fermentación oscura de Serratia marcescens (MZ413438). Los máximos valores de producción fueron de 3524.9 ± 5.1 mL/L para hidrógeno, 2611.7 ± 71 mg/L para etanol y 136.9 ± 0.3 mg/L para 3-metil-1-butanol, obtenidos para una concentración de 30 g/L. Los datos también nos muestran la sensibilidad de Serratia marcescens (MZ413438) a concentraciones de 60 g/L, obteniéndose valores de producción para hidrógeno de 1249 ± 29.2 mL/L, para etanol de 1603.2 ± 79.3 mg/L y para 3-metil-1-butanol de 100.4 ± 5.4 mg/L. Los hallazgos de este estudio incrementan la información sobre la producción de biocombustibles en el marco de un concepto de biorrefinería, y ofrecen bioprocesos alternativos para ser la generación de bioenergía a partir del tratamiento de residuos agroindustriales.
Cancer Incidence Rates in the US in 2016–2020 with Respect to Solar UVB Doses, Diabetes and Obesity Prevalence, Lung Cancer Incidence Rates, and Alcohol Consumption: An Ecological Study
Authors: Grant William B.
Published: May 2024

Abstract: This article reports the results of an ecological study of cancer incidence rates by state in the US for the period 2016-2020. The goals of this study were to determine the extent to which solar UVB doses still reduced cancer risk compared to findings reported in 2006 for cancer mortality rates for the periods 1950–1969 and 1970-1794 as well as cancer incidence rates for the period 1998–2002 and to determine which factors were recently associated with cancer risk. The cancer data for non-Hispanic white (European American) men and women were obtained from the Centers for Disease Control and Prevention. Indices were obtained for solar UVB at the surface for July 1992, and alcohol consumption, and diabetes and obesity prevalence near the 2016–2020 period. Lung cancer incidence rates were also used in the analyses as a surrogate for smoking, diet, and air pollution. The cancers for which solar UVB is significantly associated with reduced incidence are bladder, brain (males), breast, corpus uteri, esophageal, gastric, non-Hodgkin’s lymphoma, pancreatic, and renal cancer. Lung cancer was significantly associated with colorectal, laryngeal, and renal cancer. Diabetes was also significantly associated with breast, liver, and lung cancer. Obesity prevalence was significantly associated with breast, colorectal and renal cancer. Alcohol consumption was associated with bladder and esophageal cancer. Thus diet has become a very important driver of cancer incidence rates. The role of solar UVB in reducing risk of cancer has been reduced due to people spending less time outdoors, wearing sunscreen that blocks UVB but not UVA radiation, and population increases in overweight and obesity, which lowers 25-hydroxyvitamin D concentrations and generates systemic inflammation, a risk factor for cancer. The dietary approach that would reduce the risk of diabetes, obesity, lung cancer, and, therefore cancer, would be one based mostly on whole-plants and restrictions on red and processed meats and ultraprocessed foods. Solar UVB exposure for a few minutes before applying sunscreen and taking vitamin D supplements would also help reduce risk of cancer.Keywords: alcohol consumption; cancer incidence;
On the Indication from Pioneer 10/11 Data of an Anomalous Acceleration
Authors: Yi Yong Gwan
Published: May 2024

The physics of Hubble's law, motivated by the anomalous acceleration of Pioneer 10/11, suggests that the Hubble constant corresponds to a gravitational field of the Universe. The Hubble constant inferred from Pioneer 10/11 data is $\sim 69$ km/s/Mpc. The anomalous acceleration of Pioneer 10/11 can be interpreted as an observational evidence for Mach's principle. The redshift is an apparent value. Its intrinsic value has a limit resulting to $v
Navigating the Path to Management: Insights into Sport Manager Selection and Diversity Strategies in Romania
Authors: Stefanica Valentina , Joksimović Marko , İbrahim Ceylan Halil , Muntean Raul- Ioan
Published: May 2024

This study explores the complexities of sport manager selection, investigating the impact of affirmative action, recruitment strategies, organizational culture, diversity initiatives in board selection, and career advancement insights from coaches' perspectives.
To conduct this investigation, a purposive sampling technique was employed, selecting 65 prominent sports managers and coaches from Romania. Participants, aged between 35 to 58 years old, boasted an average of 10 to 20 years of sports experience and were chosen based on specific criteria, including academic qualifications.
Data collection occurred over an extended period, spanning from fall 2022 to spring 2024, through semi-structured interviews with sport managers and coaches. The findings unveiled persistent challenges in effectively implementing affirmative action measures, as sport managers grapple with balancing the promotion of deserving candidates while maintaining continuity in board culture. Achieving meaningful diversity necessitates nuanced approaches that consider both candidate quality and cultural compatibility.
Moreover, the study sheds light on coaches' perspectives when considering executive council positions, highlighting various pathways to career advancement. Recruitment practices prioritized informal methods, emphasizing board cohesion. Despite the recognized importance of diversity, challenges persist in selecting candidates solely based on demographic representation.
The study provides valuable insights into promoting diversity and inclusivity within sports organizations' executive councils. Future research directions may include exploring longitudinal trends and delving into the qualitative experiences of underrepresented groups, with the aim of advancing understanding and promoting equity within sports organizations.
Non-stationary Transformer Architecture: A Versatile Framework for Recommendation Systems
Authors: Liu Yuchen , Li Gangmin , Payne Terry R. , Yue Yong , Man Ka Lok
Published: May 2024

Recommendation systems are crucial in navigating the vast digital market. However, user data’s dynamic and non-stationary nature often hinders their efficacy. Traditional models struggle to adapt to the evolving preferences and behaviours inherent in user interaction data, posing a significant challenge for accurate prediction and personalisation. Addressing this, we propose a novel theoretical framework, the Non-stationary Transformer, designed to capture and leverage the temporal dynamics within data effectively. This approach enhances the traditional transformer architecture by introducing mechanisms accounting for non-stationary elements, offering a robust and adaptable solution for recommendation systems. Our experimental analysis, encompassing deep learning and reinforcement learning paradigms, demonstrates the framework’s superiority over benchmark models. The empirical results confirm the efficacy of our proposed framework, which not only provides significant performance enhancements, approximately 8% in Logloss reduction and up to 2% increase in F1 score but also underscores its potential applicability across accumulative reward scenarios. These findings advocate adopting Non-stationary Transformer models to tackle the complexities of today’s recommendation tasks.
Statistical Considerations for the Design and Analysis of Pragmatic Trialsin Aging Research
Authors: Kammar-García Ashuin , Fernández-Urrutia Liliana Aline , Guevara-Díaz Jorge Alberto , Mancilla-Galindo Javier
Published: May 2024

Pragmatic trials aim toassess intervention efficacy in real-world settings, contrasting with explanatory trials conducted in controlled conditions. In aging research, pragmatic trials are important designs for the obtention of real-world evidence in elderly populations, often underrepresented in trials. In this review, we discuss statistical considerations from a frequentist approach to the design and analysis of pragmatic trials. Cluster randomization necessitates careful consideration of sample size calculation and analysis methods, especially regarding missing data and outcome variables. Mixed effects models and Generalized Estimating Equations (GEE) are both recommended for analysis, with tools available for sample size estimation. Multi-arm studies pose challenges in sample size calculation, requiring adjustment for design effects and consideration of multiple comparison correction methods. Secondary analyses are common but require caution due to reduced statistical power. Safety data collection methods should balance pragmatism and data quality. Overall, understanding statistical considerations is crucial for designing rigorous pragmatic trials evaluating interventions in elderly populations under real-world conditions.
Plastic Shakedown Behavior and deformation Mechanisms of Ti17 Alloy under Long Term Creep-Fatigue Loading
Authors: Wang Jianguo , Man Tongchi , Liu Dong , Zhang Zhihong , Zhang Chi , Sun Yuxiang
Published: May 2024

Ti17 alloy is mainly used to manufacture aero-engine discs due to its excellent properties such as high strength, toughness and hardenability. It is often subjected to creep-fatigue cyclic loading in service environments. Shakedown theory describes the state in which the accumulated plastic strain of the material stabilizes after several cycles of cyclic loading, without affecting its initial function and leading to failure. This theory includes three behaviors: elastic shakedown, plastic shakedown, and ratcheting. In this paper, the creep-fatigue tests (CF) were conducted on Ti17 alloy at 300℃ to study its shakedown behavior under creep-fatigue cyclic loading. Based on the plasticity-creep superposition model, a theory model that accurately describes the shakedown behavior of Ti17 alloy was constructed, and ABAQUS finite element software was used to validate the accuracy of the model. TEM analysis was performed to observe the micro-mechanisms of shakedown in Ti17 alloy. The results reveal that the Ti17 alloy specimens exhibit plastic shakedown behavior after three cycles of creep-fatigue loading. The established finite element model can effectively predict the plastic shakedown process of Ti17 alloy, with a relative error between the experimental and simulation results within 4%. TEM results reveal that anelastic recovery controlled by dislocation bending and back stress hardening caused by inhomogeneous deformation are the main mechanisms for the plastic shakedown behavior of Ti17 alloy.
Extracts from Artemisia annua Linne’ Regulate the Translocation of p53 to Mitochondria and Induce Apoptotic Effects on LS174T Colon Cancer Cells In Vitro and In Vivo
Authors: Nam Gaewon , Kim Bo-Min , Kim Young-Min
Published: May 2024

Plant-derived compounds have been historically used for the treatment of various diseases and an important source of several clinically useful anti-cancer agents. The Artemisia annua is known as a medicinal herb that is effective against cancer. Thus, the purpose of this study was to investigate whether ethanol extracts of Artemisia annua could increase an anti-cancer effect against LS174T cells. Our results show that Artemisia annua extracts (AAE) induces apoptosis through the regulation of mitochondria outer membrane potential. We demonstrate that apoptosis is induced by p53-dependent manner when cells were treated with Nutlin-3 (MDM2 inhibitor) and LY294002 (Akt inhibitor). In addition, the apoptotic effect was also observed in the p53-independent manner through pifithrin-α (p53 inhibitor) and celecoxib (COX-2 inhibitor) treatment. As in in vitro, AAE induced apoptotic effects and regulated apoptosis-related proteins in LS174T xenograft model. Taken together, these results suggest that Artemisia annua extracts exerts an anti-cancer effect through p53-independent manner, as well as p53-dependent manner by p53´ translocation in LS174T colon cancer cells.
Insect Protein as a Component of Meat Analogue Burger
Authors: Krawczyk Anna , Fernández-López Juana , Zimoch-Korzycka Anna
Published: May 2024

Researchers are exploring solutions to meet the growing demand for protein due to the expected increase in global population by 2050. Interest in alternative protein sources like insects has risen, driven by concerns about environmental impact and the need for sustainable food production. This study aimed to develop and evaluate the physicochemical properties of soy protein-based burger enriched with insect protein from Alphitobius diaperinus. Three formulations were developed: a control (B0), and burgers with 5% (B5) and 10% (B10) insect protein - Whole Buffalo Powder (WBP). Results showed that adding insect protein decreased the burger analogue's pH. There was observed a clear trend of increasing total lipids and SFA, and decreasing MUFA and PUFA, as the WBP concentration increases from 0% to 10%. No significant differences with increasing WBP concentration in the protein content of the burger analogue, as well as the cooking yield, were noted. The WBP addition had a notable effect on the color change, especially decrease in brightness (L*). It was shown that as the WBP concentration increased, there were no significant differences in the texture profile of the burger analogues. The formulation with 5% WBP concentration was the most acceptable in sensory analysis.
New Sustainable Fintech Business Models Created by Open API Technology: A Case Study of Korea’s Open Banking API Platform
Authors: Oh Sangseung , Chung Gyongchan , Cho Keuntae
Published: May 2024

Fintech facilitates financial inclusion by introducing new sustainable and accessible business models in developing countries. Open banking API technology is used by various fintech businesses in both developing and developed countries, with varying effects on financial markets. It changes the financial market distribution structure by separating financial product manufacturing and distribution and intensifying competition between traditional financial institutions and fintech companies. Fintech companies innovate by using this tool to create new business models. In December 2019, Korea established a standardized "open banking API platform," sharing an interbank payment network with fintech companies. It has since shown explosive growth, surpassing the trading volume of the UK, the country that introduced open banking APIs for the first time. This study analyzes new business models fintech companies created using this API technology. Based on existing literature, statistics from the platform operator (the Korea Financial Telecommunications and Clearings Institute), and investigations of 30 Korean fintech mobile applications, this study analyzes new fintech business models that provide financial services using this platform. These companies create sustainable business models by combining multiple APIs. Four representative business models (simple funds transfer, simple payment, cross-border remittance, and asset management) are analyzed to reveal how fintech companies create business models with open APIs.
Mutational Profiles of Cutaneous Squamous Cell Carcinomas with Different Patterns of Clinical Aggression from Head and Neck District
Authors: Colombino Maria , Palmieri Giuseppe , Rodio Manuela , Tettamanzi Matilde , Rampazzo Silvia , Margani Raffaello , Trignano Emilio , Cossu Antonio , Fedeli Maria Antonietta , Fadda Giovanni Maria , Rubino Corrado
Published: May 2024

Cutaneous squamous cell carcinoma is a prevalent malignancy with a rising incidence and notably high mutational load. Exploring the genetic nuances of cSCC and investigating molecular approaches stands as a potential avenue for improving outcome in high-risk patients. This retrospective case-control study involved two cohorts of 14 patients (“discovery cohort”) and 12 patients (“validation cohort”) with cSCC located in head-neck anatomical district and diagnosed at pT2 stage. Overall, cases developed early local relapse of the disease whereas controls never re-lapsed during the entire follow-up period. Next generation sequencing (NGS) approach conducted on histological samples revealed that TP53 and CDKN2A were the most frequently mutated genes in our series. No specific mutation was identified as potential prognostic or therapeutic targets. Controls exhibited a tendency toward a higher mutational rate compared to cases. It is possible that an increased number of mutations could prompt the cSCC to expose more antigens, becoming more immunogenic and facilitating the recognition by the immune system. This could enhance and sustain immunological response, potentially preventing future recurrences.