bluuebunny/crossref_metadata_2025 huggingface dataset:
Photothermal tissue reconstruction and the use of phytoestrogens in the treatment of genitourinary menopausal syndrome
Authors: Kulikov I. A. , Apolikhina I. A. , Gevorkyan G. A.
Published: May 2024

Introduction. Genitourinary syndrome of menopause (GSM) is a complex of symptoms resulting from changes to the vulvovaginal region, urethra and bladder due to estrogen and other sex steroid deficiency. Vulvovaginal atrophy is one of its manifestations, and vaginal dryness, dyspareunia, burning and itching are the most common symptoms.

Aim. To analyse 20 clinical cases of the use of innovative laser procedures combined with phytoestrogens in patients with vulvovaginal atrophy as a symptom of GSM vs the standard systemic protocol for menopausal hormone therapy.

Materials and methods. A clinical case-control study was conducted among 20 postmenopausal women. The age of the subjects ranged from 50 to 65 years with amenorrhea for at least 1 year, a follicle-stimulating hormone level of >30 IU/L and various presentations of GSM. The women were divided into two groups: group 1 (n = 10) received laser therapy combined with phytoestrogens, group 2 (n = 10) received systemic menopausal hormonal therapy. To evaluate the results, a survey with a specialized international vulvovaginal symptom questionnaire (VSQ) was carried out to determine the vaginal health index scores before and after treatment.

Results. After treatment, both groups showed significant improvement in the form of the reduction or disappearance of symptoms of vulvovaginal atrophy. The prescription of phytoestrogens provided an additional positive effect after 3 sessions of carbon dioxide laser treatment.

Conclusion. The carbon dioxide laser exposure resulted in the reduction or disappearance of the local symptoms of climacteric syndrome in the form of GSM, and the use of phytoestrogens as part of Mense BAA supplemented the treatment of psychoemotional and neurovegetative changes, which allowed us to make a conclusion about the feasibility, high efficiency and safety of the complex treatment for women, who do not wish to take menopausal hormone therapy and (or) have absolute contraindications. However, further research on the laser technologies and other non-hormonal techniques to treat GSM is required to carry out a more complete and accurate assessment of the effectiveness and safety of these treatments.
Evaluation of Biological Response Elicited by Two Novel Tooth Cream Formulations of Cocos nucifera- Cell Line Studies and MTT Assay on Human Gingival Fibroblast
Authors: Balakrishnan Nivethigaa , Kumar Subramanian Aravind
Published: May 2024

The current research endeavors to assess the biological reactions induced by two newly formulated tooth creams from Cocos nucifera. Freshly harvested coconut from the Tirupur district of Tamil Nadu underwent processing to create two distinct formulations: one utilizing coconut milk and the other lyophilized coconut extract. Tooth cream samples were prepared and tested against commercial tooth cream following ISO 10993-5 recommendations. Human gingival fibroblast cells were isolated and cultured according to approved protocols, and cytotoxicity evaluations were conducted through MTT assay and live/dead staining. Results indicated high cell viability in both coconut-based formulations, comparable to the commercial tooth cream. Live/dead staining revealed predominantly live cells with minimal cytotoxic effects. Novel coconut-derived tooth creams exhibit comparable biocompatibility to commercial formulations, showing high cell viability and minimal cytotoxicity with human gingival fibroblasts. This suggests coconut-based tooth creams as safe alternatives for oral care, advocating further investigation into their efficacy and tissue safety. Overall, our findings endorse natural compound utilization in dental care formulations.
The use of neurohymnastics exercises in speech therapy work with children with disabilities
Authors: Tukalova Ekaterina Viktorovna
Published: May 2024

Abstract: The article presents the author's view on the application of neurogymnastics methods in correctional and pedagogical work with children with disabilities. Examples of exercises aimed at enhancing the interaction of the cerebral hemispheres, as well as relaxation and stimulation of nerve impulses are given. This article may be useful to specialists in the field of speech therapy, defectology, as well as kindergarten teachers.
Navigating the Gut-brain Axis: Insights into the Pathogenesis of Hepatic
Encephalopathy
Authors: Emojevwe Victory Aghogho , Shahriari Arman , Mahboobi Hamidreza
Published: May 2024

:

Hepatic encephalopathy is a neurological condition that affects people who have an insufficient
liver function. However, its pathophysiology is yet unclear. For hepatic encephalopathy,
pharmacotherapy is the primary treatment choice. Lowering ammonia levels, enhancing neurotransmitter
signal transduction, and modifying gut microbiota, tackles the pathophysiology of hepatic
encephalopathy. The intestinal microbiota of liver disease patients differs greatly from that of
healthy people, and this difference is linked to the development of hepatic encephalopathy. Additionally,
gut microbiota is intimately linked to several theories in the pathophysiology of hepatic
encephalopathy, such as the GABA-ergic tone hypothesis, bile acid circulation, ammonia poisoning
theory, and neuroinflammation, all of which exacerbate patients' cognitive and motor impairments.
Providing some probiotics or reestablishing the intestinal bacteria's balance has a substantial
impact on neurological illnesses in hepatic encephalopathy. The goal of this review is to determine
the possible metabolic impacts and microbiological pathways in the gut-brain axis mediated progression
of hepatic encephalopathy, as well as its potential function as a therapeutic target.
Determining Critical Points in Fish Distribution and Calculation of Income UD. Sumber Rezeki Laut, Tuban Regency
Authors:   Postgraduate Department of Fisheries Resources Utilization, Faculty of Fisheries and Marine Science, Bogor Agricultural University, Bogor, Iqbal Muhammad Nur , Mustaruddin Mustaruddin ,   Department of Fisheries Resources Utilization, Faculty of Fisheries and Marine Science, Bogor Agricultural University, Bogor, Kurniawati Vita Rumanti ,   Department of Fisheries Resources Utilization, Faculty of Fisheries and Marine Science, Bogor Agricultural University, Bogor, Novita Yopi ,   Department of Fisheries Resources Utilization, Faculty of Fisheries and Marine Science, Bogor Agricultural University, Bogor
Published: May 2024

This study aims to evaluate the fish distribution activities in UD. Sumber Rezeki Laut, alongside the fish handling during distribution, and critical points of fish quality decline during distribution. This research uses descriptive analysis, critical point analysis, organoleptic tests, and income analysis. Distribution handling is divided into two types, namely direct distribution handling and indirect distribution handling. The most important handling of both types of distribution includes maintaining the right temperature during the process, transferring fish to UD. Sumber Rezeki Laut, changing fish containers, cleaning and soaking fish, and distributing fish to Balekambang Market. However, the long travel distance required to distribute the fishes has the potential to reduce the quality of the fish, as evidenced by the decrease in fish quality observed during the distribution trials. Organoleptic test results showed that the quality of the fish decreased from when it was purchased until it reached the wholesaler. Meanwhile, when calculating distribution costs, the highest result for direct distribution was IDR1,335,987, and the lowest was IDR372,995. The highest income from indirect distribution was IDR1,544,001, while the lowest was IDR399,993. To ensure good fish quality, UD. Sumber Rezeki Laut needs to improve its human resource capabilities to become more efficient and produce quality products for consumers.
Devolepment Strategy Analysis of Leading Business for Fisheries Sector in Situbondo Regency
Authors:   Fisheries Result Technology Study Program, Faculty of Science and Technology, Ibrahimy University Situbondo, Ramli Ramli , Muqsith Abdul ,   Aquaculture Study Program, Faculty of Science and Technology, Ibrahimy University Situbondo, Rasidi Moh. ,   Economics Study Program, Faculty of Social & Humanities, Nurul Jadid University Probolinggo
Published: May 2024

The leading business of fisheries sector in the Situbondo District is faced with problems even though it also benefits from government support. Based on these problems and advantages, this research aims to develop leading businesses of fisheries sector in the Situbondo District through the formulation of appropriate business development strategies. The analysis method used to formulate this strategy is SWOT and QSPM analysis. The results of the SWOT analysis recommend that leading businesses of fisheries sector implement survival strategies. The priority strategies based on the QSPM matrix are 1) developing the capacity of fisheries business actors, 2) increasing supply chain performance to increase the competitiveness of fisheries businesses, 3) supporting Government policies in creating a fair fisheries business climate, 4) making production plans based on demand/market, 5) optimizing upstream production activities (catching and cultivation) through environmentally friendly production control and adequate infrastructure support, 6) controlling the quality of fish catches through providing supporting facilities and infrastructure, and 7) increasing production results by optimizing assistance provided by the Government.
The Relation Between Fisheries Counseling Capacity and Fisherman Satisfaction in Counseling Activities in Batang Gasan, Padang Pariaman Regency, West Sumatera Province
Authors:   Department of Fisheries Social Economics, Faculty of Fisheries and Marine Affairs, Riau University Bina Widya Campus Km 12.5 Simpang Baru Pekanbaru 28293, Zulkarnain Zulkarnain , Metalisa Rindi , Mahrunnisa Mahrunnisa ,   Department of Fisheries Social Economics, Faculty of Fisheries and Marine Affairs, Riau University Bina Widya Campus Km 12.5 Simpang Baru Pekanbaru 28293
Published: May 2024

Batang Gasan District, Padang Pariaman Regency, West Sumatra Province has a fisheries product processing segment, both in terms of human resources (interest and experience) and natural resources (fisheries production). The purpose of this study was to determine the capacity for counseling for fisheries workers, fishermen’s satisfaction, and the relationship between the capacity of fisheries counseling workers and fishermen satisfaction in counseling related activities. Respondents in this study were fishermen who participated in counseling activities, as many as 68 people were used as samples using accidental sampling. The data analysis technique uses the Spearman Rank correlation method (Rs). In which, the results of this study are the capacity of counseling workers as facilitators is considered good, the capacity of counseling workers as motivators and educators is considered not good and the capacity of counseling workers as communicators is considered quite good, fishermen's satisfaction with planning is considered as quite satisfied, fishermen's satisfaction with implementation and evaluation is considered as not satisfied, and the capacity of counseling workers as facilitators, motivators, educators and communicators is significantly related to fishermen's satisfaction. It is expected that the capacity of counseling workers as motivators and educators is further enhanced in counseling activities so that fishermen feel satisfaction and can make fishermen's behavior change.
Adaptive Capacity of Fishermen in Facing Tidal Floods with Vulnerability to Viability (V2V) Approach
Authors:   Professor, Faculty of Economics and Business, Diponegoro University, SBM Nugroho , Nayak Prateep Kumar ,   Assistant Professor, Faculty of Environment, University of Waterloo, Susilowati Indah ,   Professor, Faculty of Economics and Business, Diponegoro University, Furoida Aini Nur ,   Doctoral Student, Faculty of Economics and Business, Diponegoro University, Suciati Ika ,   Doctoral Student, Faculty of Economics and Business, Diponegoro University, Khasanah Siti Nur , Putra Tedy Pratama ,   Bachelor Student, Faculty of Economics and Business, Diponegoro University
Published: May 2024

Tambakrejo’s small-scale fishing households have low socio-economic capabilities and must face the problem of tidal flooding. Therefore, this research has the following objectives: 1) To identify the vulnerability of fishing households in Tambakrejo Fishermen Village to social-ecological changes due to tidal flooding. 2) To investigate the adaptive responses of fishermen households in facing socio-ecological changes due to tidal flooding. This research uses primary data by using semi-structured interviews. The number of respondents in the study was 60, determined by the snowball sampling technique. The data were analyzed using descriptive statistical methods. The results of the research show that the community is vulnerable to both natural and institutional aspects. Adaptive responses shape community resilience through increased collaboration capacity and community learning capacity. This research contributes to the government's ability to distribute assistance to the community, especially fishing households affected by tidal flooding.
KARAKTERISTIK KIMIA EKSTRAK ETANOL DAUN TENGGULUN (Protium javanicum) BERDASARKAN TINGKAT KETUAAN DAUN
Authors: Ari Yusasrini Ni Luh , Trisna Darmayanti Luh Putu
Published: May 2024

Ekstrak etanol daun tenggulun mengandung sejumlah senyawa bioaktif yang berpotensi sebagai antioksidan. Tingkat ketuaan daun adalah salah satu komponen yang mempengaruhi jumlah dan komposisi senyawa fitokimia dalam ekstrak daun tenggulun. Tujuan dari penelitian ini adalah untuk menentukan tingkat ketuaan daun yang ideal sehingga ekstrak yang dihasilkan memiliki karakteristik kimia terbaik. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) dengan 4 perlakuan tingkat ketuaan daun tenggulun yaitu P1 (daun pucuk), P2 (daun muda), P3 (daun dewasa), dan P4 (daun tua). Perlakuan diulang sebanyak 4 kali sehingga diperoleh 16 unit percobaan. Hasil penelitian menunjukkan bahwa tingkat ketuaan daun berpengaruh nyata (P<0,05) terhadap rendemen, kadar total fenol, total flavonoid, total tanin dan nilai IC50 ekstrak etanol daun tenggulun. Perlakuan terbaik diperoleh dari ekstrak etanol daun tenggulun dewasa dengan nilai rendemen 18,812%, total fenol 22,612 mg GAE/g, total flavonoid 4,330 mg QE/g, total tanin 23,392 mg TAE/g dan IC50 21,265 ppm. Terdapat hubungan korelasi negatif yang cukup antara total fenol dengan aktivitas antioksidan yang ditunjukkan dengan nilai koefisien korelasi (R) sebesar -0,70.
Harnessing nutritional immunity and advanced diagnostics for COVID-19 prevention
Authors:   Department of Chemistry College of Science, UAE University, AL Ain, Abu Dhabi, United Arab Emirates, Hakeem Muhammad Kamran , Sohail Amir ,   Department of Chemistry College of Science, UAE University, AL Ain, Abu Dhabi, United Arab Emirates, Hisaindee Soleiman ,   Department of Chemistry College of Science, UAE University, AL Ain, Abu Dhabi, United Arab Emirates, Shah Iltaf ,   Department of Chemistry College of Science, UAE University, AL Ain, Abu Dhabi, United Arab Emirates
Published: May 2024

The ongoing worldwide health crisis caused by the COVID-19 pandemic, which began in Wuhan, China, has led to infections across the globe. Although many vaccines are available, a definitive cure has yet to be found. This study examines methods to lessen the impact of the disease, focusing on preventive actions and strengthening the immune system through diets rich in vitamins and nutrients. Our investigation also considers non-traditional methods, particularly the vital role of early detection in controlling the spread of COVID-19. Accurate diagnostic techniques are essential in this effort. Surprisingly, there is a lack of comprehensive studies on the complex interactions between various vitamins, trace metals, and immunity in relation to COVID-19. Addressing this gap, our review carefully analyzes how diets enriched with vitamin D can boost immunity. Additionally, we explore worldwide challenges that impede the progress of effective and quick diagnostic methods. Our goal is to provide a thorough understanding of the current situation regarding immunity, diagnostic procedures, and treatment approaches for COVID-19. This review not only covers various diagnostic methods for SARS-CoVs but also assesses the effectiveness of different vaccines against COVID-19. Through detailed analysis, we contribute to the ongoing discussion on fighting COVID-19, providing important information for researchers, healthcare workers, and policymakers.
Written safe work procedures and their impact on a culture of prevention
Authors:   Faculty of Engineering and Architecture, Professional School of Industrial Engineering Andean University of Cusco, Cusco, Peru, Cavero Pacheco Shaili Julie , Carreño Hanco Diego Joaquin ,   Faculty of Engineering and Architecture, Professional School of Industrial Engineering Andean University of Cusco, Cusco, Peru, Moscoso Cavero Luis Ricardo ,   Faculty of Engineering and Architecture, Professional School of Industrial Engineering Andean University of Cusco, Cusco, Peru, Román- González Avid ,   Aerospace Sciences and Health Research, Laboratory (INCAS-Lab), National Technological University of South Lima, Lima, Peru
Published: May 2024

The goal of this study was to evaluate how implementing written procedures for safe work affects the preventive culture among employees at a company involved in collecting and processing coffee, cocoa, and honey. The research used a quantitative method with an experimental design and a pre-experimental sub-design for explanation. The study's participants were the company's workers, who completed the NOSACQ-50 Nordic questionnaire to assess their preventive culture before and after the WPSW was put into practice across the three production processes. This study identified the risks associated with each process, established control measures to prevent accidents, and designed safer methods for each process. The findings showed that implementing WPSW significantly improved the preventive culture among workers, leading to the conclusion that ensuring safe work conditions and fostering a preventive culture enhances worker safety and health.
Open Design to Homesickness Elements in Tuping Village for Rural Revitalization
Authors: Mao Panyun , Mokhtar S'harin , Zainal Abidin Shahriman
Published: May 2024

This paper discusses about problems facing in the rural revitalization and explore the social value of green design in promoting rural revitalization, as well as the principles and methods of rural revitalization design. From the three aspects of rural brand image design, cultural and creative product design, and rural tourism brand design based on the homesickness resources of Tuping Village. We analyzed the empirical case of Tuping Village homesickness design and social innovation project hosted by the author. In conclusion, design can play an important driving role, designers should carry out green design based on homesickness culture, maintain open collaborative innovation thinking, integrate all forces and resources, and realize the cultural inheritance and industrial revitalization of rural areas
Tracing the Cultural and Historical Evolution of Chinese Kitchens
Authors: Li Shuai , Mokhtar S'harin , Zainal Abidin Shahriman , Ren Shiyu
Published: May 2024

Chinese kitchen is now encountering difficulties. Traditional elements of the Chinese kitchen are dying out at an accelerated pace. The new-style kitchen cannot meet the needs of Chinese people. Before designing a kitchen, it is a need to study the evolution of the kitchen. Due to this, the objective of this paper is to study the historical and cultural context of Chinese kitchens through literature research. At the end of the research, the Chinese kitchen can be roughly divided into five stages: 1) birth, 2) development, 3) maturity, 4) decline, and 5) transformation.
@INNOVATIVEESCAPE: Students’ perception and perceived learning outcome using an online exhibition via Instagram platforms
Authors: Jamaludin Nor Lelawati , Mohd Nasir Junita Shariza , Isa Siti Salwa , Ali Abu
Published: May 2024

Instagram's @innovateescape channel provides social, educational, and technological opportunities. The objective of this study is to enhance comprehension of students' perspectives and perceived educational outcomes through the use of Instagram as a platform for issue-based learning. Students used issue-based learning using the Instagram feed @innovativeescape for this assignment. The findings give empirical evidence that students’ perceptions of the Instagram learning activity were favourable, resulting in a satisfactory learning outcome. These findings prompted the development of best practices for utilising the Instagram platform @innovativeescape to improve students' learning perceptions.
A Pilot Study on Lean Practice Implementation according to the Sizes and Ages of the Companies
Authors: Abu Falah , Mohd Salleh Noor Azlina , Mohamad Maheera , Ibrahim Norazura
Published: May 2024

The purpose of this paper is to address the accompanying lean manufacturing implementation barrier in terms of the sizes and ages of the companies. The 148 wood and furniture companies in Kuala Lumpur and Selangor were selected for the pilot research determinations. Smaller companies account for slightly more than 80% of newly founded and expanding wood and furniture industries, with 60% implementing lean practices. The practical implications indicate that the Malaysian furniture sector will have a promising future, with the number of medium-sized plants anticipated to increase in the upcoming years due to the increase in new and emerging businesses.
The Roles of NOTCH3 p.R544C and Thrombophilia Genes in Vietnamese Patients With Ischemic Stroke: Study Involving a Hierarchical Cluster Analysis (Preprint)
Authors: Bui Huong Thi Thu , Nguyễn Thị Phương Quỳnh , Cam Tu Ho , Nguyen Phuong Sinh , Pham Thuy Thi , Vu Thu , Nguyen Thi Thu Huyen , Khanh Ho Lam , Nguyen Tien Dung
Published: May 2024

BACKGROUND

The etiology of ischemic stroke is multifactorial. Several gene mutations have been identified as leading causes of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a hereditary disease that causes stroke and other neurological symptoms.

OBJECTIVE

We aimed to identify the variants of NOTCH3 and thrombophilia genes, and their complex interactions with other factors.

METHODS

We conducted a hierarchical cluster analysis (HCA) on the data of 100 patients diagnosed with ischemic stroke. The variants of NOTCH3 and thrombophilia genes were identified by polymerase chain reaction with confronting 2-pair primers and real-time polymerase chain reaction. The overall preclinical characteristics, cumulative cutpoint values, and factors associated with these somatic mutations were analyzed in unidimensional and multidimensional scaling models.

RESULTS

We identified the following optimal cutpoints: creatinine, 83.67 (SD 9.19) µmol/L; age, 54 (SD 5) years; prothrombin (PT) time, 13.25 (SD 0.17) seconds; and international normalized ratio (INR), 1.02 (SD 0.03). Using the Nagelkerke method, cutpoint 50% values of the Glasgow Coma Scale score; modified Rankin scale score; and National Institutes of Health Stroke Scale scores at admission, after 24 hours, and at discharge were 12.77, 2.86 (SD 1.21), 9.83 (SD 2.85), 7.29 (SD 2.04), and 6.85 (SD 2.90), respectively.

CONCLUSIONS

The variants of MTHFR (C677T and A1298C) and NOTCH3 p.R544C may influence the stroke severity under specific conditions of PT, creatinine, INR, and BMI, with risk ratios of 4.8 (95% CI 1.53-15.04) and 3.13 (95% CI 1.60-6.11), respectively (Pfisher<.05). It is interesting that although there are many genes linked to increased atrial fibrillation risk, not all of them are associated with ischemic stroke risk. With the detection of stroke risk loci, more information can be gained on their impacts and interconnections, especially in young patients.
Authors’ Response to Peer Reviews of “Establishing Antimicrobial Resistance Surveillance in the Water and Environment Sector in a Resource-Limited Setting: Methodical Qualitative and Quantitative Description of Uganda’s Experience From 2021 to 2023” (Preprint)
Authors: Katumba Godfrey , Mwanja Herman , Mayito Jonathan , Mbolanyi Betty , Isaasi Fred , Kibombo Daniel , Namumbya Judith , Musoke David , Kabazzi Jonathan , Sekamatte Musa , Idrakua Lillian , Walwema Richard , Lamorde Mohammed , Kakooza Francis , Etimu Simon
Published: May 2024

UNSTRUCTURED
Visualising patient pathways and identifying data repositories in a UK neurosciences centre (Preprint)
Authors: Biggin Fran , Knight Jo , Chandrabalan Vishnu Vardhan , Emsley Hedley CA
Published: May 2024

BACKGROUND

Health and clinical activity data are a vital resource for research, improving patient care and service efficiency. Healthcare data is inherently complex, and its acquisition, storage, retrieval, and subsequent analysis require a thorough understanding of the clinical pathways underpinning such data. Better use of healthcare data could lead to improvements in patient care and service delivery. However, this depends on the identification of relevant datasets.

OBJECTIVE

We aim to demonstrate the application of Business Process Modelling Notation to represent clinical pathways at a UK neurosciences centre and map clinical activity to corresponding data flows into electronic health records and other non-standard data repositories.

METHODS

We used Business Process Modelling Notation (BPMN) to map and visualise a patient journey and the subsequent movement and storage of patient data. After identifying several datasets which were being held outside of the approved applications. We collected information about these datasets using a questionnaire.

RESULTS

We identified 13 approved applications where neurology clinical activity was captured as part of the patient's electronic health record including applications and databases for managing referrals, outpatient activity, laboratory data, imaging, and clinic letters. We also identified 22 distinct datasets that were not approved by the hospital and were created and managed within the neurosciences department, either by individuals or teams. These were being used to deliver direct patient care and include datasets for tracking patient blood results, recording home visits, and tracking triage status.

CONCLUSIONS

Mapping patient data flows and repositories allowed us to identify areas in which the current EHR is not fulfilling the needs of day-to-day patient care. Data that is being stored outside of approved applications represents a potential duplication in effort and risks being overlooked. Future work should identify unmet data needs to inform correct data capture and centralisation within appropriate data architectures.

CLINICALTRIAL

Not Applicable
Understanding the Occurrence and Fate of Atmospheric Microplastics and Their Potential Risks to Human Health: Protocol for a Cross-Sectional Analysis (Preprint)
Authors: Hasan Shaikh Sharif , Salam Abdus , Moniruzzaman Mohammad , Bari Md Aynul , Aich Nirupam , Jahan Farjana , Rahman Mahbubur , Islam Zubayer , Kabir Md Humayun , Shaikh Md Aftab Ali , Raqib Rubhana , Parvez Sarker Masud
Published: May 2024

BACKGROUND

Plastic pollution has reached an alarming magnitude, defining the contemporary era as the “Plastic Age.” Uncontrolled plastic production and inadequate recycling processes have led to widespread contamination of the environment with micro and nanoplastics.

OBJECTIVE

The study aims to assess the environmental and human health consequences of exposure to microplastic particles (MPs) and their additives among plastic recycling workers in Dhaka. Specifically, it focuses on mapping the management pathways of plastic waste from collection to disposal, analyzing the types of MPs in the environment, and assessing the potential health impacts on plastic recycling workers.

METHODS

A cross-sectional exploratory study design was used, consisting of exposed and nonexposed groups in plastic recycling sites in Dhaka, Bangladesh. The study will establish possible associations between different health consequences and microplastic particle exposure with a systematic approach involving plastic recycling hot spot detection, management pathway mapping, and detecting the presence of environmental MP. MPs and heavy metals will be detected from environmental samples using fluorescence microscopy, Fourier-transform infrared spectroscopy, and inductively coupled plasma mass spectrometry. Human exposure will be assessed by detecting the metabolites of bisphenol and phthalates from urine samples using liquid chromatography–tandem mass spectrometry and thoroughly evaluating endocrine, reproductive, respiratory, and renal functions. The sample size was derived from the mean concentrations of urinary bisphenol and phthalates metabolites, requiring the participation of 168 respondents. A 1:1 exposure to nonexposed stratification would be sufficient to meet our study objectives, considering the conventional level of power and confidence interval. This study protocol (PR#22111) has received approval from the Research Review Committee and Ethical Review Committee of the icddr,b.

RESULTS

The project was funded in August 2022. We started collecting environmental samples in January 2023 and completed participant enrollment, exposure survey, and biological sample collection by December 2023. We enrolled 84 adult plastic recycling workers with at least 5 years of exposure history and 84 nonexposed participants who were not involved with plastic recycling activities. Data analysis is currently underway, and the first results are expected to be submitted for publication in November 2024.

CONCLUSIONS

The findings would provide valuable insights into the adverse impacts of microplastic pollution on both the environment and human health, aiding in better understanding the extent of the issue.

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/60289
Research on Green Process Innovation Enabling the Synergistic Effect of Pollution Reduction and Carbon Reduction
Authors: Wu Hongshuang , Liu Wenyi
Published: May 2024

Achieving the objective of "peak carbon dioxide emissions and carbon neutrality" in the new stage of development will require the synergistic effect of pollution reduction and carbon reduction. In the new stage of development, achieving the goal of "peak carbon dioxide emissions and carbon neutrality" will necessitate the synergistic effect of pollution reduction and carbon reduction. This study assesses the degree to which pollution reduction and carbon reduction have a synergistic effect using the coupling coordination model, and uses the fixed effect model, the dynamic panel GMM model, the OLS model and the threshold effect model to examine how green process innovation affects pollutant reduction and carbon reduction synergistically, including direct, heterogeneous, and nonlinear effects. The results show that: firstly, green process innovation has a direct promoting effect on synergistic effect of pollution reduction and carbon reduction; Secondly, due to the differences in the economic development of different regions in China, the impact of green process innovation on the synergistic effect of pollution reduction and carbon reduction is heterogeneous in different regions, and presents a gradient distribution of "east > west > middle". Finally, there is a threshold effect in the impact of green process innovation on regional synergistic effect of pollution reduction and carbon reduction. This paper provides some reference value for promoting green process innovation and enhancing the collaborative impact of mitigating pollution and decreasing carbon emissions.
Assessing the impact of off-season vegetable farming on farmers in the Savelugu Municipality in the Northern Region of Ghana
Authors: Fuseini Yakubu Jacob
Published: May 2024

The purpose of the study is to assess the impact of off-season vegetable farming on farmers in the Savelugu Municipality in the Northern Region. The study population consisted of respondents who were into off-season vegetable farming in the Savelugu Municipality in five selected communities in the Municipality. Purposive sampling technique was used for a sample size of fifty (50) off season farmers in the selected communities. Interview guide and questionnaire were used to solicit data for the study. The data were analyse in a step-by-step thematic analysis that included reading the transcriptions, coding, reviewing and naming themes. Thereafter, descriptive statistics namely frequency, means, and percentages were used to analyze the data in MS-Excel. Off-Season vegetable production technology can be practiced by maintaining or adjusting planting time, selecting of varieties, creating artificial and controlled environment through use of tunnels, polytene house, glass houses, hot bed etc. Moreso, Off-Season vegetable helps to get income showed the highest rank with the overall mean score of 1. Nearly all the trained farmers said that their main constraint was the high incidence of pests and diseases. It is evident that off-season cultivation is profitable and has significant impact on the consumption expenditure and food security status of the farmers. The policy implication of this study is that providing improved and modern agricultural inputs to off season farmers is essential in agriculture for rural development.
Colour Design in Healthcare Environments
Authors: McLachlan Fiona
Published: May 2024

This portfolio documents two related pratice-led, colour research projects at the Royal Edinburgh Mental Health Hospital. This practice-led colour research employed architectural design knowledge and emerging on-site evidence to devise colour schemes and to make site-specific wall paintings within shared areas and circulation spaces. Project 1 took place in ‘Pentland’ dementia ward from February 2017 – February 2018, and Project 2 involved the main corridor and Andrew Duncan Clinic reception area from April – November 2019. Although guidance is available for care homes and hospitals, it appears to be applied often without professional design input that can take into account light conditions, views in and out, and the social and cultural setting. Observations included monitoring the sun path, light quality, and room usage. Hand sketches were effective in communicating the conceptual ideas with large test panels of candidate paint colours. Newsletters at regular intervals kept staff, visitors and carers informed of the project and invited questions. Two themes emerged, namely ‘destinations’ and ‘directions’. Carers emphasised a need for spaces that are more homely and sophisticated, and small places within the circulation areas where patients can sit with their relatives. Feedback from the users indicated that a strong red and patterned wall panel seemed to act as a beacon and be sufficiently memorable to direct the patients at the most confusing intersections. Incidents (conflicts and arguments) were substantially reduced since the installation. Patients would sit with relatives in the circulation areas, as well as within private rooms. Staff reported that the dispersal of the patients around the ward may have diffused tensions, and therefore reduced the number of incidents between patients and staff. The work has been disseminated through peer-reviewed written output while the colour design is experienced on a daily basis by the hospital community. The projects have been disseminated through academic outputs that challenge the prevailing ‘tick box’ approach to the use of colour in health care environments.
Accident Detection and Nearby Patrol Alert System Using AI &ML
Authors: P Sumathi. , V Aravind. , S Deepak Raj. , K Gokul. , N Hariharan.
Published: May 2024

Abstract: Intelligent communities are utilizing different creative ideas to improve the quality of human life. Due to fast growing sizes of our cities, need of travelling is constantly increasing, which in turn has increased count of vehicles on the roads. Increasing number of vehicles on the roads has brought about numerous difficulties for Street Traffic Management Authorities. Amongst different traffic related issues, road accidents are something worth giving attention to and have to be on the priority list. This project describes various automatic road accident detection techniques, which automatically detect accidents using surveillance videos in real-time and intimates the event scenario to control room and the main uniqueness of the system is it automatically estimates the crash value of the incident and intimates to the user. The proposed method assumes that traffic accident events are described by visual features occurring through a temporal way. Therefore, a visual features extraction phase, followed by a temporary pattern identification, compose the model architecture. The visual and temporal features are learned in the training phase through convolution and recurrent layers using built-from-scratch and public datasets. An accuracy of 98% is achieved in the detection of accidents in public traffic accident datasets, showing a high capacity in detection independent of the road structure.
Liderazgo distribuido: plan de mejora para revertir la desvinculación en formación de profesorado
Authors: Silva Sánchez Valeria Susana , Imbert Romero Nelky Daisy
Published: May 2024

El presente estudio se basa en el liderazgo educativo desde un enfoque de liderazgo distribuido para la mejora educativa. El problema investigado es la desvinculación estudiantil en formación docente, y el objetivo del estudio es conocer las causas de la desvinculación temprana para abordarla a través de un plan de mejora, cimentado en la gestión a través del liderazgo distribuido. La metodología utilizada es la investigación educativa aplicada con el enfoque estudio de caso, de corte cualitativo con aportes de técnicas cuantitativas que enriquecieron el enfoque. Las técnicas cualitativas fueron las entrevistas y el análisis de documentos. Como complemento, se empleó la técnica de encuesta. Se aplicaron dos cuestionarios, uno a los docentes y otro a los estudiantes del grupo estudiado. Los resultados muestran que la desvinculación se debe a factores personales de los estudiantes, pero también a factores intrínsecos generados por el sistema educativo. La investigación concluye con el diseño de acciones que buscan abordar el problema con el involucramiento y participación de los docentes y de los estudiantes, a partir del liderazgo del director que lo comparte y distribuye para, de esta forma, revertir la situación a través del plan de mejora.
Quantum time dilation in a gravitational field
Authors: Paczos Jerzy , Dębski Kacper , Grochowski Piotr T. , Smith Alexander R. H. , Dragan Andrzej
Published: May 2024

According to relativity, the reading of an ideal clock is interpreted as the elapsed proper time along its classical trajectory through spacetime. In contrast, quantum theory allows the association of many simultaneous trajectories with a single quantum clock, each weighted appropriately. Here, we investigate how the superposition principle affects the gravitational time dilation observed by a simple clock – a decaying two-level atom. Placing such an atom in a superposition of positions enables us to analyze a quantum contribution to a classical time dilation manifest in spontaneous emission. In particular, we show that the emission rate of an atom prepared in a coherent superposition of separated wave packets in a gravitational field is different from the emission rate of an atom in a classical mixture of these packets, which gives rise to a quantum gravitational time dilation effect. We demonstrate that this nonclassical effect also manifests in a fractional frequency shift of the internal energy of the atom that is within the resolution of current atomic clocks. In addition, we show the effect of spatial coherence on the atom's emission spectrum.
GAYA KOMUNIKASI SEORANG PEMIMPIN DALAM MEMOTIVASI PARA DOSEN UNTUK MELAKUKAN TRIDARMA
Authors: Lumbantoruan Rachel Mia Lorenza , Napitupulu Evi Enitari , Zebua Anugerah
Published: May 2024

Seorang Pemimpin membutuhkan ketrampilan kepemimpinan dan gaya komunikasi sebagai pendukung upaya meningkatan kapasitas individu dan kinerja suatu organisasi, apapun bentuk organisasi dan dimanapun organisasi tersebut berada. Penelitian ini bertujuan untuk mengetahui gaya komunikasi dan motivasi seorang pimpinan di Universitas Sari Mutiara Indonesia (USM-Indonesia) dalam memotivasi para dosen untuk melakukan Tridarma. Peneliti menggunakan teori gaya komunikasi dan motivasi kerja dalam penelitian ini. Metode yang digunakan dalam penelitian ini adalah studi kasus yang bersifat kualitatif. Informan dalam penelitian ini adalah beberapa pimpinan yang ada di USM-Indonesia. Hasil penelirian menunjukkan bahwa Gaya komunikasi pimpinan diwujudkan melalui gaya kerja atau cara bekerjasama dengan orang lain secara konsisten. Melalui apa yang dikatakannya (bahasa) dan apa yang diperbuatnya (tindakan). Gaya komunikasi akan memberikan pengetahuan tentang bagaimana perilaku orang-orang dalam suatu lembaga ketika mereka melaksanakan tindakan dalam menyampaikan berbagai informasi dan gagasan. Pimpinan didalam suatu lembaga mempunyai ciri-ciri dan karakter yang berbeda-beda sesuai dengan kepribadiannya masing-masing. Kondisi seperti ini yang mencerminkan bahwa gaya komunikasi pimpinan setiap lembaga atau perusahaan akan berbeda.
IDENTITAS DIRI DAN ISU KESEHATAN MENTAL: INTERPRETASI REMAJA TERHADAP KONTEN PODCAST
Authors: Septiana Riyan , Briandana Rizki
Published: May 2024

Penelitian ini menganalisis Interpretasi Remaja Terhadap Pesan Isu Kesehatan Mental Pengguna Media Sosial Dalam Konten Closethedoor Podcast “Kuliah Gak Penting” di Lingkungan Kota Depok melalui saluran Youtube Deddy Corbuzier. Pembentukan identitas diri remaja saat ini tidak lepas dari peran media sosial. dalam penelitian ini, konten kuliah gak penting dikaji dari sudut pandang khalayak yang menontonnya. Penelitian ini menggunakan pendekatan analisis resepsi dengan paradigma kontruktivis. Pengumpulan data pada penelitian ini menggunakan teknik wawancara mendalam. Informan dalam penelitian ini di pilih berdasarkan kriteria yang telah dikelompokan berdasarkan tiga wilayah tempat tinggal serta pendidikan yang berbeda di lingkungan kota depok. Hasil dari penelitian pembentukan identitas diri dalam konten kuliah gak penting berada pada posisi dominan dimana informan menerima pembentukan identitas diri yang mengarah kepada pembentukan konsep identitas diri yang dibentuk berdasarkan subjek sosiologis, adapun satu informan berada dalam posisi negosiasi informan menerima pemaknaan yang diberikan dalam podcast tersebut, tetapi hanya sebagai informasi dan wawasan. posisi oposisi tidak didapatkan dalam penelitian ini karena informan bersikap secara aktif dalam pemilihan konten media, informan telah mengikuti saluran YouTube Deddy Corbuzier, dan mengikuti setiap unggahan dari konten YouTube tersebut.
A Rare Combination of Multisystem Congenital Anomalies; Interrupted Aortic Arch, Congenital Cystic Adenomatoid Malformation of the Lungs and Horseshoe Kidneys, A Case Report
Authors: H* Hidayatullah
Published: May 2024

Combinations of multisystem congenital anomalies have been frequently reported. However, this article presents a rare combination of congenital anomalies affecting the cardiovascular system, lungs, and kidneys in a neonate, which was detected through a computed tomography exam. The authors conducted a comprehensive search of the English literature and found no previous reports of such a combination in online literature.
ESTRATÉGIAS INOVADORAS PARA DESENVOLVER HABILIDADES DE LEITURA E ESCRITA ASSOCIADAS AS TECNOLOGIAS
Authors: Azevedo Celine Maria de Sousa , Emiliano Francielle Rodrigues Costa , Pereira Gêneses Soares , Silva Tatiana Petúlia Araújo da , Barbosa Brenda Silvana de Souza , Montalvo Adelita Franco , Lima Gean Paulo Trabuco , Trindade Karlla Cristina
Published: May 2024

Este estudo investigou o impacto de estratégias inovadoras no desenvolvimento das habilidades de leitura e escrita, focando o uso de tecnologias educativas. Diante do problema de como integrar efetivamente as tecnologias no processo educacional para melhorar essas habilidades essenciais, o objetivo geral foi avaliar a eficácia de tais estratégias na educação contemporânea. A metodologia adotada centrou-se na revisão de literatura, analisando trabalhos acadêmicos, relatórios de casos práticos e estudos de implementação de tecnologias, como softwares educacionais, plataformas de aprendizagem e ferramentas de colaboração online. Os resultados demonstraram que, quando aplicadas de maneira integrada e estratégica, as tecnologias educativas e metodologias ativas podem enriquecer o aprendizado de leitura e escrita. Observou-se que a personalização do ensino, facilitada pela tecnologia, promove um engajamento maior dos alunos e atende às suas necessidades individuais de aprendizagem. Contudo, a pesquisa também identificou desafios, principalmente relacionados à acessibilidade e inclusão, sugerindo a necessidade de estratégias para garantir que todos os alunos tenham igual acesso às oportunidades educacionais proporcionadas pela tecnologia. As considerações finais destacaram a importância de uma abordagem colaborativa e integrada na implementação de estratégias inovadoras, enfatizando a necessidade de formação contínua para educadores, investimento em infraestrutura e desenvolvimento de recursos educacionais inclusivos.
LETRAMENTO DIGITAL: CAPACITANDO ALUNOS PARA O MUNDO TECNOLÓGICO
Authors: Rezende Guelly Urzêda de Mello , Silva Éverton Marques da , Demuner Jocelino Antonio , Souza Leidiane Gonçalves de , Andrade Filho Marcos Antonio Soares de , Campos Stela Cristina de Oliveira , Gomes Antonio José Ferreira , Melo Júnior Hermócrates Gomes
Published: May 2024

Esta revisão bibliográfica abordou o letramento digital como um elemento fundamental na preparação de alunos para o mundo tecnológico, identificando estratégias pedagógicas e desafios enfrentados pelas instituições educacionais. O objetivo geral foi explorar como o letramento digital pode ser efetivamente integrado à educação para capacitar os alunos a participarem ativamente da sociedade digital. A metodologia adotada envolveu uma revisão sistemática da literatura, com ênfase em estudos de caso que ilustram práticas bem-sucedidas de letramento digital. Os resultados revelaram que, apesar dos desafios relacionados à infraestrutura tecnológica, formação de professores e resistências culturais, existem exemplos significativos de integração bem-sucedida do letramento digital que podem servir como modelo para outras instituições. A análise desses casos destacou a importância de estratégias pedagógicas que não apenas ensinam habilidades técnicas, mas também promovem o pensamento crítico, a criatividade e a cidadania digital. As considerações finais reforçaram a necessidade de um compromisso contínuo das instituições educacionais com a formação de professores, o investimento em infraestrutura e a adaptação às novas tecnologias, visando preparar os alunos para os desafios e oportunidades da era digital.