bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparative Genetic Association Analysis of Human Genetic Susceptibility to Pulmonary and Lymph Node Tuberculosis
Authors: Abhimanyu Abhimanyu , Bose Mridula , Giri Astha , Varma-Basil Mandira
Published: January 2023

Background: Tuberculosis (TB) manifests itself primarily in the lungs as pulmonary disease (PTB) and sometimes disseminates to other organs to cause extra-pulmonary TB, such as lymph node TB (LNTB). This study aimed to investigate the role of host genetic polymorphism in immunity related genes to find a genetic basis for such differences. Methods: Sixty-three, Single nucleotide polymorphisms (SNPs) in twenty-three, TB-immunity related genes including eleven innate immunity (SLCA11, VDR, TLR2, TLR4, TLR8, IRGM, P2RX7, LTA4H, SP110, DCSIGN and NOS2A) and twelve cytokine (TNFA, IFNG, IL2, Il12, IL18, IL1B, IL10, IL6, IL4, rs1794068, IL8 and TNFB) genes were investigated to find genetic associations in both PTB and LNTB as compared to healthy community controls. The serum cytokine levels were correlated for association with the genotypes. Results: PTB and LNTB showed differential genetic associations. The genetic variants in the cytokine genes (IFNG, IL12, IL4, TNFB and IL1RA and TLR2, 4 associated with PTB susceptibility and cytokine levels but not LNTB (p < 0.05). Similarly, genetic variants in LTA4H, P2RX7, DCSIGN and SP110 showed susceptibility to LNTB and not PTB. Pathway analysis showed abundance of cytokine related variants for PTB and apoptosis related variants for LNTB. Conclusions: PTB and LNTB outcomes of TB infection have a genetic component and should be considered for any future functional studies or studies on susceptibility to pulmonary and extra-pulmonary TB.
Synergetic Association between Anemia and Hyperuricemia on New-Onset Chronic Kidney Disease in a Large Taiwanese Population Follow-Up Study
Authors: Chen You-Chi , Liu Yi-Hsueh , Wu Pei-Yu , Huang Jiun-Chi , Su Ho-Ming , Chen Szu-Chia , Chang Jer-Ming
Published: January 2023

The incidence of chronic kidney disease (CKD) is increasing worldwide; however, the association between CKD and anemia and hyperuricemia has yet to be clarified. In addition, whether anemia and hyperuricemia only influence renal damage in combination with other comorbidities or whether they are direct causative factors is also controversial. Therefore, the aim of this longitudinal study was to investigate these issues in a large Taiwanese cohort. We enrolled 26,631 participants from the Taiwan Biobank (TWB) after excluding those with CKD at the baseline, all of whom had follow-up data for a median of 4 years. In this study, CKD was defined as an estimated glomerular filtration rate < 60 mL/min/1.73 m2, incident new-onset CKD was defined as the development of CKD during follow-up, anemia was defined as a hemoglobin level <13 mg/dL in males and <12 mg/dL in females, and hyperuricemia was defined as a serum uric acid (UA) level >7 mg/dL in males and >6 mg/dL in females. The participants were divided into four groups according to whether or not they had anemia and hyperuricemia. Multivariable analysis showed that low hemoglobin (per 1 g/dL; odds ratio [OR], 0.760; p < 0.001) and high serum UA (per 1 mg/dL; OR, 1.444; p < 0.001) in model 1 and anemia (OR, 2.367; p < 0.001) and hyperuricemia (OR, 2.516; p < 0.001) in model 2 were significantly associated with new-onset CKD. Furthermore, compared to the group without anemia or hyperuricemia, the groups with anemia without hyperuricemia (OR, 2.502; p < 0.001), without anemia with hyperuricemia (OR, 2.559; p < 0.001), and with anemia and hyperuricemia (OR, 5.505; p < 0.001) were significantly associated with new-onset CKD. There was a significant interaction between hemoglobin and serum UA and new-onset CKD (p < 0.001). In conclusion, we found that anemia and hyperuricemia were associated with new-onset CKD, respectively, and also had a synergetic effect on new-onset CKD.
Concordance of Non-Alcoholic Fatty Liver Disease and Associated Factors among Older Married Couples in China
Authors: Yuan Xueli , Liu Wei , Ni Wenqing , Sun Yuanying , Zhang Hongmin , Zhang Yan , Yin Peng , Xu Jian
Published: January 2023

Background: Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases which affects mainly middle-aged and older adults, resulting in a considerable disease burden. Evidence of concordance on NAFLD and lifestyle factors within older married couples in China is limited. This study aimed to evaluate spousal concordance regarding lifestyle factors and NAFLD among older Chinese couples. Methods: We conducted a cross-sectional study using data from 58,122 married couples aged 65 years and over recruited from Shenzhen, China during 2018–2020. Logistic regression analyses were used to estimate the reciprocal associations in NAFLD within couples after incremental adjustment for potential confounders. Results: There was a marked concordance regarding NAFLD among older married couples in our study. After adjustment for confounders, the odds of having NAFLD were significantly related to the person’s spouse also having NAFLD (1.84 times higher in husbands and 1.79 times higher in wives). The spousal concordance of NAFLD was similar, irrespective of gender. Couples with both a higher educational level and abdominal obesity were more likely to have a concordance of NAFLD compared to couples with both a lower educational level and no abdominal obesity, respectively (p < 0.05). Conclusion: Our results indicated that health care professionals should bear in mind the marked spousal concordance with respect to risk factors and NAFLD for the prevention and early detection of the highly prevalent disease in older Chinese adults.
Relationship between Body Mass Index and Physical Activity among Children from Low-Income Communities in Gqeberha, South Africa: A Cross-Sectional Study
Authors: Dolley Danielle , Du Randt Rosa , Pühse Uwe , Gerber Markus , Bosma Jacob , Aerts Ann , Adams Larissa , Arnaiz Patricia , Joubert Nandi , Müller Ivan , Nqweniso Siphesihle , Seelig Harald , Steinmann Peter , Utzinger Jürg , Walter Cheryl
Published: January 2023

This study aimed to establish the prevalence of underweight, overweight and obesity, the level of moderate-to-vigorous physical activity (MVPA) and the association thereof among vulnerable children from low-income communities in South Africa. Cross-sectional data were collected from 916 children (467 boys and 449 girls) aged 8–13 years (x̄ = 10.4 ± 1.2 years) attending eight low-income schools in Gqeberha, South Africa. Measured outcomes included accelerometery-measured physical activity (PA), weight, height and body mass index (BMI). Analysis of variance was used to determine the mean difference of total MVPA stratified by sex and BMI classification. Overall, 13% of the cohort were underweight, 19% were overweight/obese and 64% engaged in 60 min of MVPA per day. Girls presented nearly twice the odds of being overweight or obese than boys (95% CI: 1.40–2.77). Underweight to normal-weight children (boys: OR = 3.89, 95% CI: 2.18–6.93; girls: OR = 1.78, 95% CI: 1.13–2.80) were more likely to engage in 60 min/day of MVPA than overweight to obese children. There is an inverse association between BMI categories and theduration of MVPA achieved per day. Special attention should be aimed at increasing awareness of healthy nutrition and promoting a variety of PA, especially among girls and children with excess weight.
Arsenic and Heavy Metals in Sediments Affected by Typical Gold Mining Areas in Southwest China: Accumulation, Sources and Ecological Risks
Authors: Chen Sirui , Wu Pan , Zha Xuefang , Zhou Binghuang , Liu Jingbin , Long En
Published: January 2023

Gold mining is associated with serious heavy metal pollution problems. However, the studies on such pollution caused by gold mining in specific geological environments and extraction processes remain insufficient. This study investigated the accumulation, fractions, sources and influencing factors of arsenic and heavy metals in the sediments from a gold mine area in Southwest China and also assessed their pollution and ecological risks. During gold mining, As, Sb, Zn, and Cd in the sediments were affected, and their accumulation and chemical activity were relatively high. Gold mining is the main source of As, Sb, Zn and Cd accumulation in sediments (over 40.6%). Some influential factors cannot be ignored, i.e., water transport, local lithology, proportion of mild acido-soluble fraction (F1) and pH value. In addition, arsenic and most tested heavy metals have different pollution and ecological risks, especially As and Sb. Compared with the other gold mining areas, the arsenic and the heavy metal sediments in the area of this study have higher pollution and ecological risks. The results of this study show that the local government must monitor potential environmental hazards from As and Sb pollution to prevent their adverse effects on human beings. This study also provides suggestions on water protection in the same type of gold-mining areas.
Physical and Recreational Activities, Sedentary Screen Time, Time Spent with Parents and Drug Use in Adolescents
Authors: Sârbu Emanuel Adrian , Marici Marius , Bostan Simona , Gavrila-Ardelean Liviu
Published: January 2023

In a context in which sedentary screen time is on the rise and adolescents are less eager to engage in free-time activities, physical and recreational activities, although too often ignored, have proven to be an antidote for a large array of psychological and behavioral problems in adolescents, including drug use. The present study is a cross-sectional investigation of the association between physical and recreational activities, sedentary screen time, and time spent with parents and the intensity of drug use in adolescents. The participants were part of a representative sample of 2677 adolescents from Bucharest, Romania. The results indicate that vigorous physical and recreational activities, as well as time spent with parents, were negatively associated with an index of drug use (13 drugs), while screen time positively predicted the intensity of drug use. These findings raise the question of the involvement of parents and educational authorities in promoting healthy behaviors and good practices for the prevention of drug use and improving public adolescents’ health.
Mental Fatigue Degree Recognition Based on Relative Band Power and Fuzzy Entropy of EEG
Authors: Xu Xin , Tang Jie , Xu Tingting , Lin Maokun
Published: January 2023

Mental fatigue is a common phenomenon in our daily lives. Long-term fatigue can lead to a decline in a person’s operational functions and seriously affect work efficiency. In this paper, a method that recognizes the degree of mental fatigue based on relative band power and fuzzy entropy of Electroencephalogram (EEG) is proposed. The N-back experiment was used to induce mental fatigue in subjects, and the corresponding EEG signals were recorded during the experiment. A preprocessing method based on complementary ensemble empirical modal decomposition (CEEMD) and independent component analysis (ICA) was designed to remove noise from the raw EEG signal. The relative band power feature, which has been used extensively in fatigue recognition studies, was extracted from the EEG signals. Meanwhile, fuzzy entropy, a feature commonly used in attention recognition, was also extracted for fatigue recognition, based on previous findings that an increase in fatigue is accompanied by a decrease in attention. The two features were fed into an extreme gradient boosting (XGBoost) classifier to distinguish three different degrees of fatigue, which resulted in an average accuracy of 92.39% based on data from eight subjects. The promising results indicate the effectiveness of the proposed method in mental fatigue degree identification.
Direct Oral Anticoagulants versus Vitamin K Antagonists in Individuals Aged 80 Years and Older: An Overview in 2021
Authors: Azzoug Chana , Nuémi Gilles , Menu Didier , De Maistre Emmanuel , Boulin Mathieu , Putot Alain , Manckoundia Patrick
Published: January 2023

Two main types of oral anticoagulants are available in France: vitamin K antagonists (VKA) and, more recently, direct oral anticoagulants (DOAC). The benefit–risk profile appears to be favorable for DOAC, which is as effective as VKA but safer (fewer cases of severe and cerebral bleeding). In a study in 2017, we observed that older adults did not seem to receive the same modalities of oral anticoagulants as younger individuals for various reasons. To assess anticoagulation prescribing practices over time, we repeated this cross-sectional study by comparing very old individuals taking DOAC to those taking VKA. Ambulatory individuals aged 80 years and older were included. They were affiliated with the Mutualité Sociale Agricole of Burgundy and were refunded for a medical prescription of oral anticoagulation in March 2021. The demographic characteristics, registered chronic diseases (RCD), number and types of prescribed drugs, and mortality of the DOAC group and the VKA group were compared. A total of 4275 subjects were included in the study: 67.44% (2883) received DOAC and 32.56% (1392) received VKA. The two groups were similar in age. In the DOAC group, there were more women (54.98% vs. 46.98%) (p < 0.001), fewer RCD (91.47% vs. 93.68%) (p = 0.014), and lower rates of venous thromboembolism (2.53% vs. 6.75%) (p < 0.001), severe heart failure (56.50% vs. 68.03%) (p < 0.001), and severe kidney diseases (1.38% vs. 3.59%) (p < 0.001), but there were more subjects with Alzheimer’s disease (7.49% vs. 4.31%) (p = 0.001). Individuals in the DOAC group had fewer prescriptions of furosemide (48.53% vs. 55.75%) (p < 0.001) and fibrates (2.32% vs. 3.88%) (p = 0.044). They also had more prescriptions of proton pump inhibitors (43.95% vs. 39.44%) (p = 0.006) and antirheumatics (1.60% vs. 0.65%) (p = 0.009) than those in the VKA group. There was no difference in mortality. This study revealed that prescribing practices for DOAC have changed over time.
Developing a Card Game for Assessment and Intervention in the Person and the Family in Palliative Care: “Pallium Game”
Authors: Fernandes Carla Sílvia , Vale M. Belém , Magalhães Bruno , Castro João P. , Azevedo Marta D. , Lourenço Marisa
Published: January 2023

Communication between the multidisciplinary team, the person, and the family in palliative and end-of-life situations implies, in most situations, a high negative emotional burden. Therefore, innovative strategies are needed to reduce it. The goal of this study is to describe the various stages of development and validation of a collaborative card game for people in palliative care and their families. Phase one is an exploratory study, Phase two is a Delphi study, and Phase three is a multiple case study. Participants for phases 2 and 3 were recruited using a convenience sampling method. The results demonstrate in an organized and structured way the different phases required to build a collaborative card game. The use of the game was found to be useful and effective. Four categories emerged from the content analysis of the open-ended responses: usability, evaluation tool, communication and therapeutic relationship, and meaning when using the game. A collaborative game in palliative care helps to create a space for individuals and families to express feelings and experiences, meeting the myriad of physical, psychosocial, and spiritual needs. The “Pallium game” is a useful and impactful approach to discussing sensitive topics in palliative care.
Effects of a Six-Week International Tour on the Physical Performance and Body Composition of Young Chilean Tennis Players
Authors: Luna-Villouta Pablo , Paredes-Arias Marcelo , Flores-Rivera Carol , Hernández-Mosqueira Claudio , Vásquez-Gómez Jaime , Matus-Castillo Carlos , Zapata-Lamana Rafael , Faúndez-Casanova César , Jofré Hermosilla Néstor , Villar-Cavieres Natalia , Vargas-Vitoria Rodrigo
Published: January 2023

In tennis, it is common for young male tennis players to spend several weeks away from their local training camps during the competition season, which could affect their performance. The purpose of the study was to analyze the effects of a six-week international tour on physical performance and body composition in young Chilean tennis players. Twenty-four men between the ages of 14 and 16 participated in this research. In body composition and anthropometric measurement, body weight, height, skinfolds, and perimeters were measured. Body fat percentage (BFP) and skeletal muscle mass (SMM) were calculated. For physical performance, 5-m and 10-m sprints, modified agility test (MAT test), countermovement jump (CMJ), and medicine ball throw (MBT) were evaluated. Results show that, in body composition, BFP and SMM significantly decreased post-tour (p < 0.05; effect sizes ranging from 0.23 to 0.33, respectively). In physical performance, agility and 5-m and 10-m sprints significantly decreased (p < 0.05, effect sizes ranging from −0.63 to 1.10). We conclude that after a six-week international tour, BFP, SMM, agility, and speed (linear sprint) tend to decrease significantly, with a greater effect in the sprint tests.
Prevalence of Musculoskeletal Disorders among General and Technical Secondary School Students in Egypt
Authors: Atia Doaa , Elsayed Nader , Abdelmonem Asmaa , Mahmoud Sally , Mahmoud Marwa , Mohamed Kamal , Turky Khalid , Rashad Usama , Abdel Karim Amel
Published: January 2023

(1) Background: Children spend a lot of time within schools. The school setting generally has many ergonomic hazards and reinforced behavior patterns which put children at greater risk of environmental hazards than adults during their critical developmental stages. (2) Objective: The aim of the current study was to investigate the prevalence of musculoskeletal disorders (MSDs) and detect spinal deformities amongst general and technical secondary school students. (3) Methods: A total of 418 students from the second grade of secondary school in Shaquira governorate, Egypt participated in this cross-sectional study. Each student in the study was screened via Nordic Musculoskeletal Questionnaire (NMQ) and had their upper limb posture measured via RULA (Rapid Upper Limb assessment), and the deviation in their thoracic curve was measured using a scoliometer. (4) Results: There was a prevalence of MSDs amongst students as there were 69.7% of general school students and 83.8% of the technical school students suffering from MSDs with a statistically significant difference between both technical and general school students in RULA score and musculoskeletal complaints, whereas there were non-statistical differences in the scoliometer scale in both general and technical education students. (5) Conclusions: Musculoskeletal problems are prevalent among Egyptian secondary school students, with higher prevalence between technical school students. Therefore, preventive measures and strategies are recommended to overcome the future complications of these musculoskeletal disorders.
Digital Trends, Digital Literacy, and E-Health Engagement Predictors of Breast and Colorectal Cancer Survivors: A Population-Based Cross-Sectional Survey
Authors: Melhem Samar J. , Nabhani-Gebara Shereen , Kayyali Reem
Published: January 2023

Introduction: Advances in information and communication technology (ICT) and post-COVID-19 tectonic changes in healthcare delivery have made it possible for cancer survivors to obtain disease-related information for remote management online rather than through healthcare providers. To comprehend and evaluate health information, digital literacy is crucial. Objectives: This study examined cancer survivors’ information-seeking behaviour, information sources, digital health literacy, and digital trends, as well as potential determinants of e-health information receptivity and online resource use. Methods: A national 30-item cross-sectional survey using a representative random sample of cancer survivors from Jordan’s cancer registry was conducted. Chi-square tests established categorical variable relationships. Using the mean and standard deviation, we calculated the Likert scale’s ordinal data average. A p-value < 0.05 was statistically significant. Logistic regression identified predictors of interest in late-trajectory information acquisition and use of e-health platforms (apps, portals) for cancer self-management. Results: Lower digital literacy and electronic searching were associated with older age and lower income, education, and employment status (p ≤ 0.001). Digital literacy independently predicted m-health app use for remote management and interest in cancer supportive care information. Digitally literate survivors preferred the use of digital platforms (p ≤ 0.001). Information acquisition barriers included “reliability” (26%, n = 25) and “health information trustworthiness” (16.2%, n = 25). Following treatment completion, Internet-seeking behaviour decreased significantly when compared to the early cancer trajectory. Conclusion: Our findings imply that Jordanian cancer survivors’ low digital literacy may hinder information acquisition and technology-enabled cancer care. Digital interventions for cancer survivors should be adaptable to varying levels of digital health literacy. Healthcare policymakers should recognise digital inequities and devise focused initiatives to bridge the digital divide while responding to the urgent need to digitalise cancer care delivery.
Reproducibility and Scientific Integrity of Big Data Research in Urban Public Health and Digital Epidemiology: A Call to Action
Authors: Quiroga Gutierrez Ana Cecilia , Lindegger Daniel J. , Taji Heravi Ala , Stojanov Thomas , Sykora Martin , Elayan Suzanne , Mooney Stephen J. , Naslund John A. , Fadda Marta , Gruebner Oliver
Published: January 2023

The emergence of big data science presents a unique opportunity to improve public-health research practices. Because working with big data is inherently complex, big data research must be clear and transparent to avoid reproducibility issues and positively impact population health. Timely implementation of solution-focused approaches is critical as new data sources and methods take root in public-health research, including urban public health and digital epidemiology. This commentary highlights methodological and analytic approaches that can reduce research waste and improve the reproducibility and replicability of big data research in public health. The recommendations described in this commentary, including a focus on practices, publication norms, and education, are neither exhaustive nor unique to big data, but, nonetheless, implementing them can broadly improve public-health research. Clearly defined and openly shared guidelines will not only improve the quality of current research practices but also initiate change at multiple levels: the individual level, the institutional level, and the international level.
Efficient SCAN and Chaotic Map Encryption System for Securing E-Healthcare Images
Authors: Kiran Kiran , Gururaj H. L. , Almeshari Meshari , Alzamil Yasser , Ravi Vinayakumar , Sudeesh K. V.
Published: January 2023

The largest source of information in healthcare during the present epidemic is radiological imaging, which is also one of the most difficult sources to interpret. Clinicians today are forced to rely heavily on therapeutic image analysis that has been filtered and sometimes performed by worn-out radiologists. Transmission of these medical data increases in frequency due to patient overflow, and protecting confidentiality, along with integrity and availability, emerges as one of the most crucial components of security. Medical images generally contain sensitive information about patients and are therefore vulnerable to various security threats during transmission over public networks. These images must be protected before being transmitted over this network to the public. In this paper, an efficient SCAN and chaotic-map-based image encryption model is proposed. This paper describes pixel value and pixel position manipulation based on SCAN and chaotic theory. The SCAN method involves translating an image’s pixel value to a different pixel value and rearranging pixels in a predetermined order. A chaotic map is used to shift the positions of the pixels within the block. Decryption follows the reverse process of encryption. The effectiveness of the suggested strategy is evaluated by computing the histogram chi-square test, MSE, PSNR, NPCR, UACI, SSIM, and UQI. The efficiency of the suggested strategy is demonstrated by comparison analysis. The results of analysis and testing show that the proposed program can achieve the concept of partial encryption. In addition, simulation experiments demonstrate that our approach has both a faster encryption speed and higher security when compared to existing techniques.
Spot Welding Parameter Tuning for Weld Defect Prevention in Automotive Production Lines: An ML-Based Approach
Authors: Bayır Musa , Yücel Ertuğrul , Kaya Tolga , Yıldırım Nihan
Published: January 2023

Spot welding is a critical joining process which presents specific challenges in early defect detection, has high rework costs, and consumes excessive amounts of materials, hindering effective, sustainable production. Especially in automotive manufacturing, the welding source’s quality needs to be controlled to increase the efficiency and sustainable performance of the production lines. Using data analytics, manufacturing companies can control and predict the welding parameters causing problems related to resource quality and process performance. In this study, we aimed to define the root cause of welding defects and solve the welding input value range problem using machine learning algorithms. In an automotive production line application, we analyzed real-time IoT data and created variables regarding the best working range of welding input parameters required in the inference analysis for expulsion reduction. The results will help to provide guidelines and parameter selection approaches to model ML-based solutions for the optimization problems associated with welding.
Intraguild Predation of Hippodamia variegata on Aphid Mummies in Cotton Field
Authors: Dou Shuying , Liu Bing , Liu Yangtian , Zhang Jianping , Lu Yanhui
Published: January 2023

Intraguild predation among arthropod predators in agricultural ecosystems may have a negative impact on biological control. At present, there are few direct reports on trophic relationships among participants of predation in field groups. In this study, we measured the feeding choices of Hippodamia variegata (Goeze) towards mummies with different densities of Aphis gossypii Glover. The dynamics of the occurrence of mummies in the cotton field were investigated over 2017–2019. Singleplex PCR and multiplex PCR were used to detect the predation of 2090 H. variegata individuals on aphids and mummies in Xinjiang cotton field, which revealed the intraguild predation frequency between H. variegata and various parasitoids. There was no obvious feeding preference of H. variegata towards live aphids or mummies, which mainly depended on the relative density of prey. Among the four species of aphids detected in H. variegata, A. gossypii had a high detection rate and was the main prey source of the ladybeetle in the cotton filed. Mostly, ladybeetles consumed parasitoids through mummies, with 6.39% directly feeding on adult parasitoids. H. variegata had strong trophic links to both parasitoids and aphids. We established a food web of aphids–primary parasitoids–hyperparasitoids–H. variegata, which can be used to evaluate the pest control ability of H. variegata from a new perspective.
One-Piece Zirconia Oral Implants for the Support of Three-Unit Fixed Dental Prostheses: Three-Year Results from a Prospective Case Series
Authors: Kohal Ralf-Joachim , Vach Kirstin , Butz Frank , Spies Benedikt Christopher , Patzelt Sebastian Berthold Maximilian , Burkhardt Felix
Published: January 2023

The objective was to investigate the clinical and radiological outcome of one-piece zirconia oral implants to support three-unit fixed dental prostheses (FDP) after three years in function. Twenty-seven patients were treated with a total of 54 implants in a one-stage surgery and immediate provisionalization. Standardized radiographs were taken at implant placement, after one year and after three years, to evaluate peri-implant bone loss. Soft-tissue parameters were also assessed. Linear mixed regression models as well as Wilcoxon Signed Rank tests were used for analyzing differences between groups and time points (p < 0.05). At the three-year evaluation, one implant was lost, resulting in a cumulative survival rate of 98.1%. The mean marginal bone loss amounted to 2.16 mm. An implant success grade I of 52% (bone loss of ≤2 mm) and success grade II of 61% (bone loss of ≤3 mm) were achieved. None of the evaluated baseline parameters affected bone loss. The survival rate of the zirconia implants was comparable to market-available titanium implants. However, an increased marginal bone loss was observed with a high peri-implantitis incidence and a resulting low implant success rate.
Piezoresistivity and AC Impedance Spectroscopy of Cement-Based Sensors: Basic Concepts, Interpretation, and Perspective
Authors: Elseady Amir A. E. , Lee Ivan , Zhuge Yan , Ma Xing , Chow Christopher W. K. , Gorjian Nima
Published: January 2023

Cement-based sensors include conductive fillers to achieve a sensing capability based on the piezoresistivity phenomenon, in which the electrical resistivity changes with strain. The microstructural characterisation of cement-based sensors can be obtained using a promising non-destructive technique, such as AC impedance spectroscopy (ACIS), which has been recently used by many researchers. This paper reviews the fundamental concepts of piezoresistivity and ACIS in addition to the comparison of equivalent circuit models of cement-based sensors found in the literature. These concepts include piezoresistivity theory, factors affecting piezoresistivity measurement, resistance measurement methodology, strain/damage sensing, causes of piezoresistivity, theories of conduction, AC impedance spectroscopy theory, and the equivalent circuit model. This review aims to provide a comprehensive guide for researchers and practitioners interested in exploring and applying different techniques to self-sensing concrete.
The Influence of Time, Atmosphere and Surface Roughness on the Interface Strength and Microstructure of AA6061–AA1050 Diffusion Bonded Components
Authors: Ben-Haroush Michael , Mittelman Brigit , Shneck Roni , Priel Elad
Published: January 2023

Diffusion bonding experiments followed by tensile testing were conducted on cylindrical pairs of AA6061–AA1050 aluminum alloys. The influence of bonding time, atmosphere and surface roughness on the resulting interface strength was studied. Metallurgical characterization was performed to study the quality of the bonded interface for different process conditions, and also to investigate the process of oxide formation on the specimen surface. Finite element analysis of the bonding experiments was used to study the thermo-mechanical fields during the bonding process. Using a cohesive zone approach for modelling the bonded interface, the bond strength for the different process parameters was quantified. The results demonstrate that high bond strength can be obtained even for specimens bonded in an air furnace, provided the surface roughness is low. When the surface roughness increases, specimens bonded in air show a reduction in interface strength, which is not observed for specimens bonded in vacuum. Inspection of the bonded interface suggests that this reduction in interface strength can be attributed to oxidation and pockets of air trapped between the asperities of the contact surface, which hinder diffusion and plastic flow.
Pavement Performance Investigation of Asphalt Mixtures with Plastic and Basalt Fiber Composite (PB) Modifier and Their Applications in Urban Bus Lanes Using Statics Analysis
Authors: Jiu Xueyang , Xiao Peng , Li Bo , Wang Yu , Kang Aihong
Published: January 2023

A new type of plastic and basalt fiber composite (PB) modifier, which is composed of waste plastic and basalt fiber using a specific process, was used for bus lanes to address severe high-temperature deformation diseases due to the heavy loads of buses. The dense gradations of asphalt mixture with a nominal maximum aggregate size of 13.2 mm (AC-13) and 19 mm (AC-20) were selected to fabricate asphalt mixtures. The impact of the modifier PB on the high-temperature rutting resistance, low-temperature crack resistance, and water damage resistance was investigated experimentally. The experimental results showed that adding the modifier PB could enhance the rutting resistance and water damage resistance of asphalt mixtures significantly while maintaining the low-temperature crack resistance. Then, PB-modified asphalt mixtures of AC-13 and AC-20 were employed into a typical pavement structure of a bus lane in Yangzhou city, China, and three types of designed pavement structures were proposed. On this basis, statics analyses of all of the designed structures were performed using the finite element method. The statics analyses revealed that, compared with the standard axle load, the actual over-loaded axle made the pavement structure of the bus lane suffer a 30% higher stress and vertical deformation, leading to accelerated rutting damage on the bus lanes. The addition of the modifier PB could make the pavement structure stronger and compensate for the negative effect caused by the heavy axle load. These findings can be used as a reference for the pavement design of urban bus lanes.
The Stiffness Behavior of Asphalt Mixtures with Different Compactness under Variable Confinement
Authors: Dan Hancheng , Yang Penghao , Cao Wei , Shan Hongyu , Zhang Zhi
Published: January 2023

The dynamic modulus is a key property determining the short- and long-term performance of asphalt pavement, and its strong dependence on confining pressure and material density (mixture compactness) has been clearly indicated in the literature. It is always challenging to reproduce three-dimensional in situ stress conditions in the laboratory. To alleviate this difficulty, in this study, a convenient experimental setup was developed, in which the lateral confinement was made present and variable as a concomitant reaction of the surrounding materials to the vertical loading. Three dense-graded mixtures were prepared to a set of four different densities and then subjected to the confined dynamic modulus test. The results indicated a significant dependence of the confined modulus on the three factors of temperature, frequency, and compactness and that the mixture with coarser gradation demonstrated a less sensitivity to these parameters. A mathematical model was developed for the dynamic modulus master curve unifying these factors by means of horizontal shifting due to the time–temperature superposition principle (validated against the variable confinement at different compactness) and the vertical shift factor as a function of reduced frequency and compactness. The adequacy of the model was demonstrated using the experimental data, and its potential application in field pavement compaction was discussed.
Supplementation of Polymeric Reservoirs with Redox-Responsive Metallic Nanoparticles as a New Concept for the Smart Delivery of Insulin in Diabetes
Authors: Uskoković Vuk
Published: January 2023

Type 1 diabetes is caused by the inability of the pancreatic beta cells to produce sufficient amounts of insulin, an anabolic hormone promoting the absorption of the blood glucose by various cells in the body, primarily hepatocytes and skeletal muscle cells. This form of impaired metabolism has been traditionally treated with subcutaneous insulin injections. However, because one such method of administration does not directly correspond to the glucose concentrations in the blood and may fail to reduce hyperglycemia or cause hypoglycemia, the delivery of insulin in a glucose-dependent manner has been researched intensely in the present and past. This study tested the novel idea that the supplementation of polymeric reservoirs containing insulin with metallic nanoparticle precursors responsive to the redox effect of glucose could be used to create triggers for the release of insulin in direct response to the concentration of glucose in the tissue. For that purpose, manganese oxide nanoparticles were dispersed inside a poly(ε-caprolactone) matrix loaded with an insulin proxy and the resulting composite was exposed to different concentrations of glucose. The release of the insulin proxy occurred in direct proportion to the concentration of glucose in the medium. Mechanistically, as per the central hypothesis of the study, glucose reduced the manganese cations contained within the metal oxide phase, forming finer and more dissipative zero-valent metallic nanoparticles, thus disrupting the polymeric network, opening up pores in the matrix and facilitating the release of the captured drug. The choice of manganese for this study over other metals was justified by its use as a supplement for protection against diabetes. Numerical analysis of the release mechanism revealed an increasingly nonlinear and anomalous release accompanied by a higher diffusion rate at the expense of chain rigidity as the glucose concentration increased. Future studies should focus on rendering the glucose-controlled release (i) feasible within the physiological pH range and (ii) sensitive to physiologically relevant glucose concentrations. These technical improvements of the fundamental new concept proven here may bring it closer to a real-life application for the mitigation of symptoms of hyperglycemia in patients with diabetes.
Impact of Bismuth Incorporation into (Ga,Mn)As Dilute Ferromagnetic Semiconductor on Its Magnetic Properties and Magnetoresistance
Authors: Andrearczyk Tomasz , Levchenko Khrystyna , Sadowski Janusz , Gas Katarzyna , Avdonin Andrei , Wróbel Jerzy , Figielski Tadeusz , Sawicki Maciej , Wosinski Tadeusz
Published: January 2023

The impact of bismuth incorporation into the epitaxial layer of a (Ga,Mn)As dilute ferromagnetic semiconductor on its magnetic and electromagnetic properties is studied in very thin layers of quaternary (Ga,Mn)(Bi,As) compound grown on a GaAs substrate under a compressive misfit strain. An addition of a small atomic fraction of 1% Bi atoms, substituting As atoms in the layer, predominantly enhances the spin–orbit coupling strength in its valence band. The presence of bismuth results in a small decrease in the ferromagnetic Curie temperature and a distinct increase in the coercive fields. On the other hand, the Bi incorporation into the layer strongly enhances the magnitude of negative magnetoresistance without affecting the hole concentration in the layer. The negative magnetoresistance is interpreted in terms of the suppression of weak localization in a magnetic field. Application of the weak-localization theory for two-dimensional ferromagnets by Dugaev et al. to the experimental magnetoresistance results indicates that the decrease in spin–orbit scattering length accounts for the enhanced magnetoresistance in (Ga,Mn)(Bi,As).
Numerical Investigation on the Mechanical Properties of Vault Void Lining and Steel Plate Strengthening
Authors: Shao Shuai , Wu Yimin , Fu Helin , Feng Sheng , Zhang Jiawei
Published: January 2023

To study the mechanism of vault lining under different void heights and verify the strengthening effect of the attached steel plate, a CDP (concrete-damaged plasticity) model and the XFEM (extended finite element method) were used to construct the local numerical model of the vault void, and an experiment was carried out for verification. The strengthened structure of the steel plate was assembled with a combination of a two-component epoxy adhesive and chemical anchor bolts. Five lining models with various void thicknesses, together with their strengthened models, were evaluated. The results of the established numerical model were compared with the experimental results in terms of failure mode, vertical displacement, and load-deformation results. The results of the two numerical models were in good agreement with the experimental results, revealing the failure mechanism of the vault lining. The rigidity of the specimen after steel plate strengthening was significantly improved. When the void height was one-fourth of the secondary lining thickness, the lining cracks were reduced from 14 to 4, and the distribution width of the cracks was also reduced from 1.047 to 0.091 m after steel plate strengthening. The level of damage caused by cracking was significantly reduced, which proves the effectiveness of the surface-sticking method for steel plate strengthening.
Quality of Phosphate Rocks from Various Deposits Used in Wet Phosphoric Acid and P-Fertilizer Production
Authors: Ryszko Urszula , Rusek Piotr , Kołodyńska Dorota
Published: January 2023

Phosphate rocks (PRs) play a crucial role in ensuring the availability of phosphorous for the world’s food needs. PRs are used to manufacture phosphoric acid in the wet process as well as P-fertilizers. The chemical and mineralogical compositions of PRs from Djebel Onk (Algeria), Khneifiss (Syria), Negev (Israel), Bou Craa (Morocco), and Khouribga (Morocco) are discussed in this study. PRs were characterized by inductively coupled plasma optical emission spectrometry (ICP-OES), cold vapor atomic absorption spectrometry (CVAAS), ion chromatography (IC), and X-ray diffraction (XRD), as well as gravimetric and potentiometric methods. All PRs were mainly composed of CaO, P2O5, SiO2, F, SO3, Na2O, MgO, Al2O3, Fe2O3, SrO, and K2O at the level of wt.%. The P2O5 content accounted for 28.7–31.2%, which indicates that these are beneficial rocks to a marketable product. The degree of PR purity expressed by the minor elements ratio index (MER index) varied from 2.46% to 10.4%, and the CaO/P2O5 weight ratio from 1.6 to 1.9. In addition, the occurrence of trace elements such as As, Cd, Cr, Cu, Hg, Mn, Ni, Pb, Ti, V, U, and Zn, as well as Cr(VI) and Cl ions at the level of mg∙kg−1 was found. Since PRs will be used to produce P-fertilizers, their composition was compared with the regulatory parameters set up by EU Regulation 2019/1009 related to the heavy metals (As, Cd, Pb, Ni, Hg, Cu, Zn) and Cr(VI) contents in inorganic fertilizers. The heavy metals and Cr(VI) content in all PRs did not exceed the limit values. XRD analysis revealed that fluorapatite, hydroxyapatite, carbonate fluorapatite, and carbonate hydroxyapatite were the dominant minerals. The accuracy and precision of the used methods were evaluated by analysis of standard reference materials (SRM) for Western Phosphate Rock (NIST 694). The recovery was 85.3% for U and 109% for K2O, and the RSD ranged from 0.67% to 12.8%.
Determination of the Dielectric Constant of Niobium Oxide by Using Combined EIS and Ellipsometric Methods
Authors: Fitzner Krzysztof , Stępień Michał
Published: January 2023

Combining ellipsometric and EIS methods, the dielectric constant ε for the oxide Nb2O5 at room temperature was determined. At first, the linear dependence between anodization voltage and oxide thickness was established in the form d = 2.14 (± 0.05) · U + 12.2 (± 1.7) nm in the range of anodizing potentials 0–50 V. Next, assuming the equivalent circuit corresponds to one, the capacitance C of the dense oxide layer was measured. All results taken together gave the value of dielectric constant ε = 93 ± 5.
Thermodynamic Irreversibility Analysis of Thermal Radiation in Coal-Fired Furnace: Effect of Coal Ash Deposits
Authors: Zhang Chong , Zhang Zhongnong , Lou Chun
Published: January 2023

In this paper, a three-dimensional (3-D) high-temperature furnace filled with a gas-solid medium was investigated, and the radiative transfer equation and the radiative entropy transfer equation in the chamber were applied in order to analyze the effect of coal deposits on thermal radiation. The heat flux on the walls of the furnace and the entropy generation rate were determined due to the irreversibility of the radiative heat transfer process in the furnace. Furthermore, the effect of ash deposits on the wall surface on the irreversibility of the radiation heat transfer process was investigated. The numerical results show that when burning bituminous and sub-bituminous coal, ash deposits in the furnace led to a 48.2% and 63.2% decrease in wall radiative heat flux and a 9.1% and 12.4% decrease in the radiative entropy rate, respectively. The ash deposits also led to an increase in the entropy generation number and a decrease in the thermodynamic efficiency of the radiative heat transfer process in the furnace.
Improving the Separation Properties of Polybenzimidazole Membranes by Adding Acetonitrile for Organic Solvent Nanofiltration
Authors: Won Ga Yeon , Park Ahrumi , Yoo Youngmin , Park You-In , Lee Jung-Hyun , Kim In-Chul , Cho Young Hoon , Park Hosik
Published: January 2023

In research on membranes, the addition of co-solvents to the polymer dope solution is a common method for tuning the morphology and separation performance. For organic solvent nanofiltration (OSN) applications, we synthesized polybenzimidazole (PBI) membranes with high separation properties and stability by adding acetonitrile (MeCN) to the dope solution, followed by crosslinking with dibromo-p-xylene. Accordingly, changes in the membrane structure and separation properties were investigated when MeCN was added. PBI/MeCN membranes with a dense and thick active layer and narrow finger-like macrovoids exhibited superior rejection properties in the ethanol solution compared with the pristine PBI membrane. After crosslinking, they displayed superior rejection properties (96.56% rejection of 366-g/mol polypropylene glycol). In addition, the membranes demonstrated stable permeances for various organic solvents, including acetone, methanol, ethanol, toluene, and isopropyl alcohol. Furthermore, to evaluate the feasibility of the modified PBI OSN membranes, ecamsule, a chemical product in the fine chemical industry, was recovered. Correspondingly, the efficient recovery of ecamsule from a toluene/methanol solution using the OSN process with PBI/MeCN membranes demonstrated their applicability in many fine chemical industries.
Optical Sensing Technologies to Elucidate the Interplay between Plant and Microbes
Authors: Neelam Asia , Tabassum Shawana
Published: January 2023

Plant-microbe interactions are critical for ecosystem functioning and driving rhizosphere processes. To fully understand the communication pathways between plants and rhizosphere microbes, it is crucial to measure the numerous processes that occur in the plant and the rhizosphere. The present review first provides an overview of how plants interact with their surrounding microbial communities, and in turn, are affected by them. Next, different optical biosensing technologies that elucidate the plant-microbe interactions and provide pathogenic detection are summarized. Currently, most of the biosensors used for detecting plant parameters or microbial communities in soil are centered around genetically encoded optical and electrochemical biosensors that are often not suitable for field applications. Such sensors require substantial effort and cost to develop and have their limitations. With a particular focus on the detection of root exudates and phytohormones under biotic and abiotic stress conditions, novel low-cost and in-situ biosensors must become available to plant scientists.