bluuebunny/crossref_metadata_2025 huggingface dataset:
Harvesting cereals at Tappeh Sang-e Chakhmaq and the introduction of farming in Northeastern Iran during the Neolithic
Authors: Pichon Fiona , Ibáñez Estevez Juan José , Anderson Patricia C. , Tsuneki Akira
Published: August 2023

Tappeh Sang-e Chakhmaq is the only Neolithic site in Northeastern Iran, characterised by aceramic and ceramic levels corresponding to an occupation of 1500 years from the eighth to the end of the sixth millennium BCE. The Western and Eastern Mounds represent the oldest and longest occupation among the sites identified East of the Zagros, providing a unique context to explore the origin and spread of farming outside the core area of the Eastern Fertile Crescent. We present data about the first harvesting activities in the Northeastern Iranian Central Plateau by applying usewear and microtexture analysis through confocal microscopy on sickle gloss blades. Our results indicate a community of pioneer farmers who settled down in the area carrying with them both domestic cereals as well as advanced techniques of cereal cultivation. We demonstrate that most of the tools were used for harvesting cereals in a fully ripened state collected near the ground, indicating a well-established cereal cultivation strategy. The use of straight shafts with parallel inserts in Tappeh Sang-e Chakhmaq, as known in some sites in the Zagros, suggests the dispersal of farming practices and technologies from the Eastern Fertile Crescent north-eastward across Iran. We observe an evolution in the degree of ripeness of harvested cereals along the first four levels of occupation of the Western Mound, where semi-ripe harvesting is relatively important, suggesting that domestic cereals to be harvested before full maturity were introduced into the village. From the topmost of the Western Mound and along the occupation of the Eastern Mound, ripe harvesting is dominant, showing a well-established cultivation strategy of fully mature cereal. This shift could indicate an in-situ evolution towards a better-established agricultural technology, including harvesting riper crops, that would have resulted in higher yields, as cereals were collected when the grain was fully formed.
Combining GAN with reverse correlation to construct personalized facial expressions
Authors: Yan Sen , Soladié Catherine , Aucouturier Jean-Julien , Seguier Renaud
Published: August 2023

Recent deep-learning techniques have made it possible to manipulate facial expressions in digital photographs or videos, however, these techniques still lack fine and personalized ways to control their creation. Moreover, current technologies are highly dependent on large labeled databases, which limits the range and complexity of expressions that can be modeled. Thus, these technologies cannot deal with non-basic emotions. In this paper, we propose a novel interdisciplinary approach combining the Generative Adversarial Network (GAN) with a technique inspired by cognitive sciences, psychophysical reverse correlation. Reverse correlation is a data-driven method able to extract an observer’s ‘mental representation’ of what a given facial expression should look like. Our approach can generate 1) personalized facial expression prototypes, 2) of basic emotions, and non-basic emotions that are not available in existing databases, and 3) without the need for expertise. Personalized prototypes obtained with reverse correlation can then be applied to manipulate facial expressions. In addition, our system challenges the universality of facial expression prototypes by proposing the concepts of dominant and complementary action units to describe facial expression prototypes. The evaluations we conducted on a limited number of emotions validate the effectiveness of our proposed method. The code is available at https://github.com/yansen0508/Mental-Deep-Reverse-Engineering.
Surface integrity optimization for ball-end hard milling of AISI D2 steel based on response surface methodology
Authors: Huang Weimin , Wan Cong , Wang Guijie , Zhang Guosong
Published: August 2023

This study focuses on systematically revealing how cutting parameters influence the surface integrity of ball-end hard milled surface of AISI D2 steel and proposing optimization scheme from surface integrity, wear resistance and fatigue resistance perspective based on response surface methodology respectively. Results can be summarized into three aspects. Firstly, radial depth of cut with percent contribution ratio (PCR) 62.05% has a decisive influence on surface roughness, followed by spindle speed 13.25% and feed per tooth 6.63%. The work hardening degree was raised from 12.5% to 38.4% when spindle speed changed from 8000 rpm to 2000 rpm. Spindle speed and radial depth of cut are the most significant factor influencing residual stress. The PCR of spindle speed and radial depth of cut reached 73.47% and 18.63% for residual stress in feed direction, 47.11% and 37.51% in step-over direction, respectively. High residual compressive stress can be generated by lowering spindle speed and radial depth of cut benefiting from the aggravated squeeze between ball-end milling cutter and workpiece. Secondly, too small feed per tooth or too small radial depth of cut should be avoided from wear resistance point because though the surface microhardness can be improved, the surface quality will also be deteriorated. The combination of high spindle speed, small feed per tooth together with small radial depth of cut can meet the wear resistance and the machining efficiency requirement. Finally, a medium-sized cutting parameter combination should be adopted to realize satisfying material removal rate and fatigue resistance. This study can be used to guide the selection of cutting parameters during ball-end milling of hardened AISI D2 steel for dies/molds manufacturing industries.
Pseudomonas aeruginosa pulmonary infection results in S100A8/A9-dependent cardiac dysfunction
Authors: Kumar Naresh , Pestrak Matthew J. , Wu Qian , Ahumada Omar Santiagonunez , Dellos-Nolan Sheri , Saljoughian Noushin , Shukla Rajni Kant , Mitchem Cortney F. , Nagareddy Prabhakara R. , Ganesan Latha P. , William Lafuse P. , Wozniak Daniel J. , Rajaram Murugesan V. S.
Published: August 2023

Pseudomonas aeruginosa (P.a.) infection accounts for nearly 20% of all cases of hospital acquired pneumonia with mortality rates >30%. P.a. infection induces a robust inflammatory response, which ideally enhances bacterial clearance. Unfortunately, excessive inflammation can also have negative effects, and often leads to cardiac dysfunction with associated morbidity and mortality. However, it remains unclear how P.a. lung infection causes cardiac dysfunction. Using a murine pneumonia model, we found that P.a. infection of the lungs led to severe cardiac left ventricular dysfunction and electrical abnormalities. More specifically, we found that neutrophil recruitment and release of S100A8/A9 in the lungs activates the TLR4/RAGE signaling pathways, which in turn enhance systemic inflammation and subsequent cardiac dysfunction. Paradoxically, global deletion of S100A8/A9 did not improve but aggravated cardiac dysfunction and mortality likely due to uncontrolled bacterial burden in the lungs and heart. Our results indicate that P.a. infection induced release of S100A8/9 is double-edged, providing increased risk for cardiac dysfunction yet limiting P.a. growth.
Annual G20 scorecard – Research performance 2023
Authors: Rogers Gordon
Published: August 2023

The Institute for Scientific Information (ISI)™ releases an annual G20 scorecard that summarizes and compares the research and innovation capabilities of the G20 economies, known for their significant investments in education, research and technology. The G20 scorecard serves as a vital reference for researchers, technologists and policymakers due to shifting global research trends. The scorecard and its rich array of interactive data is now available in a dynamic online format to enhance accessibility and allow for rapid comparative analyses, alongside a downloadable executive summary highlighting key findings for 2023.
Points, Should Be Considered by The Employers of The Hospitality Businesses for Increasing Loyalty Among Employees in Bangladesh
Authors: Islam Md. Rafiul
Published: August 2023

It’s very important to enhance the loyal behaviour of employees to get more success in the tourism and hospitality industry and compete with the competitors. The study is based on the employees of Hotel Royal International. If employees get satisfied what hospitality business owners would serve them then productivity and efficiency will reach the goal in a satisfactory manner. But if not, then the productivity and efficiency will fall apart. The objective of the study is to identify the factors of employee job satisfaction with reasons behind job dissatisfaction and to give some recommendations based on the findings that will help the hotel industry to gain the best output in productivity and efficiency. To satisfy the aim of this study data are collected from 80 employees through the questionnaire and analyzed it by using some statistical tools. In this research some factors are found that are preferred by the employees; they are satisfied with working environment, they are satisfied with Co-worker’s cooperation, they see the personal and professional growth in the organization, they are satisfied with your regular assigned activities etc. Some negative factors are identified in this research also; the employees haven’t got the training they need to do the job, they are not satisfied with the level of increment, they don’t feel flexible in Career development system, they think that their salaries don’t match to their responsibilities and they are not satisfied with the overall job security. The recommendations in that case are to give proper trainings to the employees required for the job, they re-think about their salary and increment, provide them ways to improve their flexibility in career development and overall job security.
Nigeria’s Anti-Corruption Model: Time for a Review
Authors: Odusote Olugbemisola T
Published: August 2023

Corruption and its challenges to the society is not a new phenomenon but designing effective methods to combat it has proven to be challenging for a few reasons. They include the fact that the phenomenon is ever evolving, and the perpetrators are usually ahead of the law. Another reason is that the absence of commitment on the government has prevented sincere assessment of measures introduced to combat corruption. This paper assesses Nigeria’s Anti-corruption model of criminalisation of corruption related offences. Effective criminalisation of corruption related offences requires a workable legal framework and effective institutions. The absence of either or both means that combating corruption would not be effective. This paper discusses Nigeria’s legal framework for combating corruption. Using qualitative method, this paper finds that the legal and institutional frameworks need to be strengthened. One area of strengthening is that the anti-corruption model of multi-agencies with the two foremost Anti-Corruption Agencies (ACA), the Independent and Corruption Practices Commission (ICPC) and the Economic and Financial Crimes Commission (EFCC) be reviewed. Instead, Nigeria should consider merging these two foremost institutions. The political will of the government is however sine qua non if this is to be achieved.
Justice Collaborator in the Perspective of Indonesian Criminal Law
Authors: Saragih Radisman
Published: August 2023

The determination of a justice collaborator is to expose and dismantle these organized criminal groups. This involves gathering information about the main actors behind the organized crimes, understanding the structure of these criminal organizations, and uncovering the activities, flow of funds, and records of these organized crimes. In this context, a justice collaborator plays a crucial role as a key to revealing criminal activities. The purpose of this research is to understand the legal provisions regarding the status of a justice collaborator in providing testimony in criminal cases and the legal protections afforded to them. Several references governing the requirements for someone to become a justice collaborator are outlined in the Supreme Court Circular Letter (SEMA) No. 4 of 2011 concerning treatment for Whistleblowers and Justice Collaborators, as well as Law No. 13 of 2006 concerning the protection of witnesses and victims, and other relevant legislation. The role of justice collaborator in assisting law enforcement is essential. The importance of legal protection for justice collaborators and special treatment and leniency in punishment becomes crucial to shed light on previously obscure criminal events. However, there is still no specific, clear, and definitive regulation regarding the establishment and procedural determination of a justice collaborator. Rules concerning the protection of justice collaborators should be detailed and clear since the cooperation of witness perpetrators is vital for the disclosure of crimes such as corruption, but their testimony can also expose them to significant risks that must be addressed for their protection.
Analyzing the Impact of Cardinality Estimation on Execution Plans in Microsoft SQL Server
Authors: Lee Kukjin , Dutt Anshuman , Narasayya Vivek , Chaudhuri Surajit
Published: August 2023

Cardinality estimation is widely believed to be one of the most important causes of poor query plans. Prior studies evaluate the impact of cardinality estimation on plan quality on a set of Select-Project-Join queries on PostgreSQL DBMS. Our empirical study broadens the scope of prior studies in significant ways. First, we include complex SQL queries containing group-by, aggregation, outer joins and sub-queries from real-world workloads and industry benchmarks. We evaluate on both row-oriented and column-oriented physical designs. Our empirical study uses Microsoft SQL Server, an industry-strength DBMS with a state-of-the-art query optimizer that is equipped with techniques to optimize such complex queries. Second, we analyze the sensitivity of plan quality to cardinality errors in two ways by: (a) varying the subset of query sub-expressions for which accurate cardinalities are used, and (b) introducing progressively larger cardinality errors. Third, query processing techniques such as bitmap filtering and adaptive join have the potential to mitigate the impact of cardinality estimation errors by reducing the latency of bad plans. We evaluate the importance of accurate cardinalities in the presence of these techniques.
Consistent Range Approximation for Fair Predictive Modeling
Authors: Zhu Jiongli , Galhotra Sainyam , Sabri Nazanin , Salimi Babak
Published: August 2023

This paper proposes a novel framework for certifying the fairness of predictive models trained on biased data. It draws from query answering for incomplete and inconsistent databases to formulate the problem of consistent range approximation (CRA) of fairness queries for a predictive model on a target population. The framework employs background knowledge of the data collection process and biased data, working with or without limited statistics about the target population, to compute a range of answers for fairness queries. Using CRA, the framework builds predictive models that are certifiably fair on the target population, regardless of the availability of external data during training. The framework's efficacy is demonstrated through evaluations on real data, showing substantial improvement over existing state-of-the-art methods.
Normalizing Property Graphs
Authors: Skavantzos Philipp , Link Sebastian
Published: August 2023

Normalization aims at minimizing sources of potential data inconsistency and costs of update maintenance incurred by data redundancy. For relational databases, different classes of dependencies cause data redundancy and have resulted in proposals such as Third, Boyce-Codd, Fourth and Fifth Normal Form. Features of more advanced data models make it challenging to extend achievements from the relational model to missing, non-atomic, or uncertain data. We initiate research on the normalization of graph data, starting with a class of functional dependencies tailored to property graphs. We show that this class captures important semantics of applications, constitutes a rich source of data redundancy, its implication problem can be decided in linear time, and facilitates the normalization of property graphs flexibly tailored to their labels and properties that are targeted by applications. We normalize property graphs into Boyce-Codd Normal Form without loss of data and dependencies whenever possible for the target labels and properties, but guarantee Third Normal Form in general. Experiments on real-world property graphs quantify and qualify various benefits of graph normalization: 1) removing redundant property values as sources of inconsistent data, 2) detecting inconsistency as violation of functional dependencies, 3) reducing update overheads by orders of magnitude, and 4) significant speed ups of aggregate queries.
A Deep Dive into Common Open Formats for Analytical DBMSs
Authors: Liu Chunwei , Pavlenko Anna , Interlandi Matteo , Haynes Brandon
Published: August 2023

This paper evaluates the suitability of Apache Arrow, Parquet, and ORC as formats for subsumption in an analytical DBMS. We systematically identify and explore the high-level features that are important to support efficient querying in modern OLAP DBMSs and evaluate the ability of each format to support these features. We find that each format has trade-offs that make it more or less suitable for use as a format in a DBMS and identify opportunities to more holistically co-design a unified in-memory and on-disk data representation. Our hope is that this study can be used as a guide for system developers designing and using these formats, as well as provide the community with directions to pursue for improving these common open formats.
Epistemic Parity: Reproducibility as an Evaluation Metric for Differential Privacy
Authors: Rosenblatt Lucas , Herman Bernease , Holovenko Anastasia , Lee Wonkwon , Loftus Joshua , McKinnie Elizabeth , Rumezhak Taras , Stadnik Andrii , Howe Bill , Stoyanovich Julia
Published: August 2023

Differential privacy (DP) data synthesizers are increasingly proposed to afford public release of sensitive information, offering theoretical guarantees for privacy (and, in some cases, utility), but limited empirical evidence of utility in practical settings. Utility is typically measured as the error on representative proxy tasks, such as descriptive statistics, multivariate correlations, the accuracy of trained classifiers, or performance over a query workload. The ability for these results to generalize to practitioners' experience has been questioned in a number of settings, including the U.S. Census. In this paper, we propose an evaluation methodology for synthetic data that avoids assumptions about the representativeness of proxy tasks, instead measuring the likelihood that published conclusions would change had the authors used synthetic data, a condition we call epistemic parity. Our methodology consists of reproducing empirical conclusions of peer-reviewed papers on real, publicly available data, then re-running these experiments a second time on DP synthetic data and comparing the results.

We instantiate our methodology over a benchmark of recent peer-reviewed papers that analyze public datasets in the ICPSR social science repository. We model quantitative claims computationally to automate the experimental workflow, and model qualitative claims by reproducing visualizations and comparing the results manually. We then generate DP synthetic datasets using multiple state-of-the-art mechanisms, and estimate the likelihood that these conclusions will hold. We find that, for reasonable privacy regimes, state-of-the-art DP synthesizers are able to achieve high epistemic parity for several papers in our benchmark. However, some papers, and particularly some specific findings, are difficult to reproduce for any of the synthesizers. Given these results, we advocate for a new class of mechanisms that can reorder the priorities for DP data synthesis: favor stronger guarantees for utility (as measured by epistemic parity) and offer privacy protection with a focus on application-specific threat models and risk-assessment.
FASTgres: Making Learned Query Optimizer Hinting Effective
Authors: Woltmann Lucas , Thiessat Jerome , Hartmann Claudio , Habich Dirk , Lehner Wolfgang
Published: August 2023

The traditional and well-established cost-based query optimizer approach enumerates different execution plans for each query, assesses each plan with costs, and selects the plan that promises the lowest costs for execution. However, the optimal execution plan is not always selected. To steer the optimizer in the right direction, many query optimizers provide configuration parameters called query optimizer hints. These hints can be set for every single query separately. To show the great potential of these hints for the optimization of analytical queries, we present results of a comprehensive and in-depth evaluation using three benchmarks and two different versions of the open-source database system PostgreSQL. In particular, we highlight that query optimizer hinting is a non-trivial challenge. To solve this challenge, we propose
FASTgres
, a learning-based context-aware classification strategy for hint set prediction. Compared to related work,
FASTgres
provides transparent and direct hint set predictions with consistent performance improvements. In our end-to-end evaluation, we demonstrate that
FASTgres
effectively reduces benchmark runtimes by a factor of up to 3.25x with only steering the cost-based optimizer.
Sex differences in skeletal muscle size, function, and myosin heavy chain isoform expression during post‐injury regeneration in mice
Authors: You Jae‐Sung , Barai Pallob , Chen Jie
Published: August 2023

Skeletal muscle regeneration is an essential process to restore muscle function after injury and is influenced by various factors. Despite the known importance of sex hormones in muscle regeneration, whether and what sex difference exists in this process is still unclear. In this study, we provide evidence for a clear sex difference in muscle regeneration in mice. At 7 and 14 days after barium chloride‐induced muscle injury, female mice showed a faster recovery of muscle fiber size than males. Consistently, muscle force in female mice was restored faster than in males after injury, and this functional difference was maintained at 14 months of age when regenerative capacity declined. Myosin heavy chain isoform profiling and fatigability test revealed dynamic remodeling of myosin heavy chain isoform expression including a type IIB to IIA/X MHC transition and reduced fatigability in regenerated muscles compared to uninjured muscles. A significant sex difference was detected in myosin heavy chain IIX content, although this did not lead to different fatigability. Together, our results suggest that sex is an important determinant of the recovery of regenerating skeletal muscle and is partially involved in the remodeling of myosin heavy chain isoforms during muscle regeneration.
Inter-agency Cooperation Within the SRM: Legal and Operational Challenges for the Cooperation Between Banking Supervision and Resolution Authorities in the EU and With Third-country Authorities
Authors: Binder Jens-Hinrich
Published: August 2023

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In bank resolution, swift and effective cooperation of different actors is of essence, particularly in cross-border cases. While the same can be said about cross-border insolvency management generally, the European framework for the recovery and resolution of failing banks and, in particular, the centralisation of resolution powers within the Single Resolution Mechanism stand out as particularly complex – and, at the same time, remains to some extent untested to the present date. Against this backdrop, the present article explores the statutory framework for cooperation between the Single Resolution Board, the European Central Bank in its capacity as supervisory authority within the Single Supervisory Mechanism, National Resolution Authorities and Third Country authorities. It concludes that, while the legal and institutional arrangements governing inter-agency cooperation are generally sound, operationalisation in actual cases might still be exposed to unexpected disruptions, especially in cases where political interests are at stake.
Priority strategic directions in adolescent health in Iran based on the WHO’s Global Accelerated Action for the Health of Adolescents
Authors: Omidimorad Afsaneh , Nazari Maryam , Bahmanziari Najmeh , Soleymani Mohammad Haddad , Barakati Seyyed Hamed , Ardalan Gelayol , Aminaee Tahereh , Taghizadeh Rahim , Motlagh Mohammad Esmail , Heidarzadeh Abtin
Published: August 2023

Objectives

In line with the World Health Organization’s Global Accelerated Action for the Health of Adolescents (AA-HA!) guidance, the goal of the current research was to identify critical strategies for adolescents’ health and to determine the role and distribution of responsibilities among the leading players in the field of adolescent health in Iran.

Methods

The current qualitative and applied study is part of the Ministry of Health and Medical Education’s “Adolescent, Youth and School Health” plan to develop the “National Adolescent Health Plan Document” in 2020. First, stakeholder analysis was done, then a pool of nationally appropriate strategies was selected from the list of priority strategies recommended by the WHO in the AA-HA! through several group sessions. After that, the experts selected priority strategies based on the criteria of feasibility, acceptability, effectiveness, guaranteed resources, coordination with other plans and temporal priority, scoring, and executive priorities. Eventually, the priority strategies were assigned to different players/stakeholders in the field over several sessions bearing in mind the methods of implementation and the target groups.

Results

The experts identified 58 priority strategies/actions for adolescent health under the seven priority areas of positive development, sexual protection, reproductive health, mental health, substance abuse, self-harm, violence, unintentional injury, communicable and non-communicable diseases, nutrition, and physical activity.

Conclusions

The highest identified priority areas were in the areas of vaccination; special health care package for service providers; training and education to promote health literacy and self-care, life skills, sexual awareness, and prevention/protection against violence; community-based mental health services, planning for adolescents’ spare time, substance use prevention.
Nix interacts with WIPI2 to induce mitophagy
Authors: Bunker Eric N , Le Guerroué François , Wang Chunxin , Strub Marie‐Paule , Werner Achim , Tjandra Nico , Youle Richard J
Published: August 2023

Nix is a membrane‐anchored outer mitochondrial protein that induces mitophagy. While Nix has an LC3‐interacting (LIR) motif that binds to ATG8 proteins, it also contains a minimal essential region (MER) that induces mitophagy through an unknown mechanism. We used chemically induced dimerization (CID) to probe the mechanism of Nix‐mediated mitophagy and found that both the LIR and MER are required for robust mitophagy. We find that the Nix MER interacts with the autophagy effector WIPI2 and recruits WIPI2 to mitochondria. The Nix LIR motif is also required for robust mitophagy and converts a homogeneous WIPI2 distribution on the surface of the mitochondria into puncta, even in the absence of ATG8s. Together, this work reveals unanticipated mechanisms in Nix‐induced mitophagy and the elusive role of the MER, while also describing an interesting example of autophagy induction that acts downstream of the canonical initiation complexes.
Pedagogía para la paz para la convivencia escolar en los estudiantes de la Institución Educativa de Enseñanza Media (IEFEM) de Quibdó, Chocó: una secuencia didáctica
Authors: Muñoz Gómez Liliana Paola , Guerrero Mosquera Nidia
Published: August 2023

El presente artículo es el resultado de una investigación llevada a cabo en el contexto educativo a partir de un marco metodológico de la investigación acción. Su objetivo principal es generar una secuencia didáctica desde la pedagogía para la paz hacia el fomento de la convivencia escolar en los estudiantes del grado 7° de la Institución Educativa de Enseñanza Media (IEFEM) de Quibdó, Chocó. En la investigación participaron 212 estudiantes de grado séptimo. Se desarrollaron entrevistas estructuradas, la información recolectada fue interpretada desde matrices textuales, que organizan atribuciones y significados sobre la autopercepción de la competencia social. En los resultados se logró el diseño de una secuencia didáctica para el fomento de la convivencia escolar en contextos violentos a nivel social; para lo cual se diseñó, ejecutó y evaluó cada una de las estrategias mediante entrevistas, diarios de campo y registros anecdóticos cuyo fin pretendía involucrar a los participantes en la totalidad del proceso.
B-mode and Doppler ultrasound of bitches’ kidneys with mammary neoplasia submitted to adjuvant chemotherapy
Authors: Silva Lígia O. Pinto da , Santos Márcia Carolina S. , Pina Bianca F. , Souza Guilherme N. , Ferreira Maria de Lourdes G.
Published: August 2023

ABSTRACT: Mammary neoplasia represents the most frequently diagnosed type of neoplasia in bitches. Although surgical removal is the procedure of choice for therapeutic management, chemotherapy protocols appear as important allies and adjuvants. Despite the great advances that have occurred in the field of cancer therapy, the systemic repercussions of these drugs still impose important limitations on their use. In this sense, the development of increasingly targeted therapeutic protocols and preventive monitoring of patients represent important strategies to avoid possible complications - among them, Acute Kidney Injury (AKI). Routinely, ultrasound evaluation is used to identify morphological or metastatic variations in abdominal cavity organs. Acting complementary to the B-mode evaluation, Doppler mapping proves to be efficient in recognizing alterations in vascular hemodynamics. Therefore, the objective of the present study was to evaluate the use of B-mode and Doppler ultrasound to identify renal morphological and hemodynamic alterations in bitches with mammary neoplasia submitted to adjuvant chemotherapy protocols that associate gemcitabine with carboplatin. Thirteen bitches were included, without distinction of breed and between seven and 13 years of age. The animals were evaluated ultrasonographically at two different times during three consecutive chemotherapy cycles: before (T0) and one and a half hours after each cycle (T1), for 42 days. No morphological changes were observed in B-mode throughout the chemotherapy protocol. However, the Doppler velocimetry indices demonstrated statistical differences before (T0) and after (T1) the administration of the drugs. It was concluded that Doppler ultrasound could be used as a complementary method for monitoring the renal response of patients exposed to nephrotoxic drugs and potentially causing renal injury.
Câncer de mama e covid-19: redução no diagnóstico e tratamento em uma Unidade Hospitalar de Pernambuco
Authors: Silva Rosalva Raimundo da , Lyra Tereza Maciel , Luna Carlos Feitosa , Pedroza Robervam de Moura , Albuquerque Emídio Cavalcanti de , Brito Ana Maria de
Published: August 2023

Resumo Objetivos: analisar o impacto da pandemia da covid-19 nos atendimentos para rastreamento, diagnóstico e tratamento do câncer de mama em Pernambuco, Nordeste do Brasil. Métodos: estudo transversal, com base em dados secundários de consultas com mastologista, ultrassonografia, mamografia, biópsias, casos novos, quimioterapia, radioterapia e cirurgia, realizadas em mulheres para o rastreamento, diagnóstico e tratamento do câncer de mama, de janeiro a dezembro dos anos 2019 a 2021. Resultados: a pandemia da covid-19 reduziu as consultas com a mastologia (46,3%), ultrassonografias (34,8%), mamografia (41,5%), biópsia (49,6%), casos novos 45,7% e cirurgia 34,6% no ano de 2020 em relação ao ano de 2019. Por outro lado, com exceção das consultas com mastologista e cirurgias, todos os serviços onde se observou redução significativa em 2020, aumentaram significativamente em 2021 e voltaram ao patamar de produção do período pré-pandemia. A pandemia não afetou negativamente a oferta de quimioterapia e radioterapia. Conclusões: os achados deste estudo apontam impactos negativos na atenção ao câncer de mama, em decorrência da covid-19, durante o primeiro ano da pandemia, sobretudo nas consultas com mastologista e cirurgia, que continuaram com baixa produção em 2021. É razoável supor que a redução constatada nos procedimentos poderá refletir em um aumento de diagnósticos tardios e maior taxa de mortalidades nos próximos anos.
Agronomic efficiency of fermented composts in organic fertilization management of butterhead lettuce and green leaf lettuce
Authors: Souza Junior José B de , Guerra José Guilherme M , Goulart Jhonatan M , Silva Larissa O da , Espindola José Antonio A , Araújo Ednaldo da S
Published: August 2023

ABSTRACT This work aimed to evaluate the agronomic efficiency of fermented composts formulated with brewery waste (RC) with castor bean bran (FM) or Gliricidia sepium leaf bran (FG) in the fertilization of butterhead lettuce and green leaf lettuce grown in succession. The experimental design was in randomized blocks in a 2x5 factorial scheme, consisting of two fermented composts and five N doses (0, 50, 100, 200, and 400 kg/ha). The composts were formulated by combining 60 RC+40 FM and 60 RC+40 FG considering the % of dry matter after moisture correction. We verified that the phytotechnical performance of the butterhead lettuce, in relation to fertilization, is influenced by the applied dose; no difference regarding the composts was noticed, though. The doses of 272.2 and 248.71 kg/ha of N enabled the maximum yield of 78.01 and 87.79 t/ha, respectively, 60 RC+40 FM and 60 RC+40 FG. The fermented compost containing FM, in the range of the stipulated doses, showed a residual effect on the main phytotechnical traits of the green leaf lettuce, and the magnitude of the effect is directly proportional to the dose applied in the previous crop.
Physiological and yield parameters of wheat as affected by tiller removal and defoliation
Authors: Fioreze Samuel Luiz , Borga Iury , Ribeiro Elisandra Cristina
Published: August 2023

Abstract The objective of this work was to evaluate the photosynthetic parameters, yield potential, and response to defoliation of wheat (Triticum aestivum) plants subjected to tiller removal. Two experiments were conducted under greenhouse conditions. In the first, the two following cultivars were evaluated for complete tiller removal: TBIO Audaz and BRS 394, with a high and low tillering capacity, respectively. In the second, only 'TBIO Audaz' was subjected to detillering and defoliation at post-anthesis. Tiller removal increased the yield potential of the main stem of both tested cultivars and the CO2 assimilation potential of the flag leaf, which was possibly a strategy to meet the demands for an increased sink strength, as evidenced by the response curves to irradiance and leaf internal CO2 concentration. The partial defoliation of 'TBIO Audaz' increased daily CO2 assimilation, both in intact and detillered plants. Detillered plants show a higher photosynthetic and yield potential of the main stem, but also a greater sensitivity to defoliation in the post-anthesis period.
MÉTODOS DE ENSINO APRENDIZAGEM SOBRE PRIMEIROS SOCORROS PARA GRADUANDOS DE ENFERMAGEM: UMA REVISÃO INTEGRATIVA
Authors: Sena Aline Sampaio Rolim de , Santos Milton Lucas Pereira dos , Lima Cássia Rafaela Pereira , Santos Cícero Yago Lopes dos , Meneses Ian Alves , Xavier Samyra Paula Lustoza , Pinheiro Woneska Rodrigues
Published: August 2023

O estudo tem por objetivo identificar através das evidências científicas métodos de ensino e aprendizagem utilizados com graduandos em Enfermagem na disciplina de primeiros socorros. Trata-se de uma revisão integrativa da literatura, realizada por meio da busca dos descritores DeCs e MeSH, operadores booleanos AND e OR utilizando a estratégia PVO, para delimitar a questão norteadora: Quais os métodos de ensino e aprendizagem utilizados com graduandos em Enfermagem na disciplina de primeiros socorros? Os critérios de inclusão consistiram: estudos originais, sem restrição de idiomas, artigos publicados nos últimos cinco anos, justificando-se o recorte temporal pela perspectiva de identificar métodos de ensino atuais utilizados pelos cursos de graduação de enfermagem mediante a atualização das Diretrizes Curriculares Nacionais do curso de Enfermagem atualizada pela Resolução Nº 573 de janeiro de 2018. Excluídos, os artigos de revisão, relatos de experiência, cartas, editoriais, jornais, teses, dissertações, monografias, livros, estudos que não abordam temática relevante para o estudo da revisão e estudos duplicados. A busca foi realizada pareada, nos meses de abril e maio de 2023, por meio do portal de periódicos da CAPES, nas bases de dados selecionadas: BDENF, LILACS, MEDLINE/PubMed®), SciVerse Scopus e Web of Science. Sendo inclusos nove estudos. Conclui-se que, dos métodos de ensino em primeiros socorros para graduandos de enfermagem identificados, foram as metodologias ativas, com ênfase as simulações realísticas, uso de tecnologias educacionais, aulas expositivas dialogadas, aprendizagem baseada em problemas, programas com integração de métodos teóricos e práticos e utilização de recursos como vídeos, conferências, orientações, manequins e outros.
མཐོ་རིམ་སོབ་གྲྭའི་སོབ་ཕྲུག་ཚུ་ལུ་ གཡུས་ཀྱི་ངག་གཤིས་ལས་བརྟེན་ཏེ་ རོང་ཁའི་རྗོད་སྒྲ་ལུ་ དཀའ་ངལ་གྱི་ཁྱད་པར་ འཚོལ་ཞིབ།
Authors: Tharchen Samten
Published: August 2023

ད་ལོ་ཚུན་ཚོད་ འབྲུག་རྒྱལ་ཁབ་ཀྱི་རོང་ཁག་དང་ ལུང་ཕོགས་ཁག་ལས་ཕར་ གཡུས་སྐད་མ་འདྲཝ་ ཤར་ཕོགསཔ་ ལོ་མཚམས་ ཁེངས་ཁ་ཟེར་ ལེ་ཤ་ར་སབ་སོལ་ཡོད་པའི་ངག་གཤིས་ཚུ་ལས་ རྒྱལ་ཡོངས་ཀྱི་ཁ་སྐད་རོང་ཁ་འདི་ སབ་པའི་སྐབས་ལུ་ རྗོད་སྒྲ་མ་དགཔ་ ག་དེ་སྦེ་ར་འབྱུང་དོ་ཡོདཔ་ཨིན་ན་ ཞིབ་འཚོལ་གྱི་ཐོག་ལས་ ཡིག་ཐོག་ལུ་བཀོད་བཀོདཔ་མི་འདུག། དེ་འབདཝ་ལས་ གཡུས་སྐད་སོ་སོ་ལུ་བརྟེན་ཏེ་ རོང་ཁའི་གསལ་བྱེད་དང་མགོ་འདོགས། སྔོན་འཇུག་ཡོདཔ་དང་མེད་པའི་མིང་ཚིག། རྗེས་འཇུག་ཞུགས་ཡོད་པའི་མིང་ཚིག་དང་ དམིགས་བསལ་རོང་ཁའི་རྗོད་སྒྲ་སོ་སོ་ཡོད་པའི་མིང་ཚིག་ཚུའི་རྗོད་སྒྲ་མ་དགཔ་ ག་དེ་སྦེ་ར་ཡོད་ག་ ཁ་གསལ་སྦེ་ཧ་གོ་ཚུགས་ནིའི་དོན་ལས་ མཐོ་རིམ་སོབ་གྲྭའི་སོབ་ཕྲུག་ཚུ་ལུ་ གཡུས་ཀྱི་ངག་གཤིས་ལས་བརྟེན་ཏེ་ རོང་ཁའི་རྗོད་སྒྲ་ལུ་ དཀའ་ངལ་གྱི་ཁྱད་པར་ འཚོལ་ཞིབ་ཟེར་བའི་ དོན་ཚན་ཐོག་ལུ་ གཡུས་སྐད་ཁག་མ་འདྲཝ་བརྒྱད་ལས་ བཅའ་མར་གཏོགས་མི་སོབ་ཕྲུག་ ཕོ་མོ་ཡོངས་བསོམས་ ༨༠ ལུ་ ཁུངས་བཙན་ཐབས་ལམ་ ལ་རོག་དང་ཡིག་ཆ་དབྱེ་དཔྱད་གཉིས་ ལག་ལེན་འཐབ་སྟེ་ ཞིབ་འཚོལ་འབད་བའི་སྐབས་ལུ་ སྤྱིར་བཏང་ སོབ་ཕྲུག་གེ་ར་ལུ་ཁྱབ་མཉམ་སྦེ་ ཡོད་པའི་རྗོད་སྒྲའི་དཀའ་ཅིག་དང་། དམིགས་བསལ་ གཡུས་སྐད་སོ་སོ་སབ་མི་ལུ་ཡོད་པའི་རྗོད་སྒྲའི་དཀའ་ངལ་ཅིག་སྦེ་ དཀའ་ངལ་ཁག་གཉིས་ཡོདཔ་སྦེ་ ཐོན་ཏེ་ཡོད་མི་ཚུ་ ཞིབ་འཚོལ་སྙན་འདི་ནང་ལུ་ ཁ་གསལ་སྦེ་བཀོད་དེ་ཡོདཔ་ཨིན
Enabling environment and support as determinant of quality in ECCD centres in Bhutan: An analysis of the findings of quality monitoring of ECCD centres in Bhutan
Authors: Gayleg Karma
Published: August 2023

Quality in Early Childhood Care and Development (ECCD) centres is central to the effectiveness of programmes they provide but it is not limited to what early educators do with children on a daily basis emphasize that quality in early childhood education encompasses such facets as how engaging and safe the centre is, if there is a range of strategies and activities employed to make learning experiences meaningful, whether families and communities engage in the educational process, and if there is a systemic support from the larger community for the effective functioning of the centre. Recognizing the centrality of a holistic definition of early childhood education, the design of centres in Bhutan is founded on internationally accepted concepts and approaches that integrate critical aspects of quality learning environment. The Bhutan Quality Framework, with four specific domains and 29 indicators, define quality in terms of not just focusing on learning activities and strategies, but also encompassing child safety and well-being, quality of interaction and communication, and family and community involvement.This paper is essentially a report on the state of ECCD centres across the country, generated on the basis of assessment carried out using the quality monitoring tool for ECCD centres. The paper highlights the status of ECCD centres in terms of quality of learning in general and analyzes the levels of attainment in each of the four domains of quality. The paper further specifies the state of quality in ECCD centres by districts and types of centres to illustrate their strengths and weaknesses in varying situations and environments. The paper analyses the key findings of the survey and provides a number of recommendations that could contribute to heightening quality of ECCD programmes by addressing shortfalls in the different aspects of quality in ECCD centres
Contributions to the taxonomy and biogeography of the genus Dichagyris (subg. Dichagyris) Lederer, 1867 (Lepidoptera, Noctuidae, Noctuinae) II. : The review of the D. forficula species group
Authors: Varga Zoltán , Ronkay Gábor , Ronkay László
Published: August 2023

The forficula species group of the Holarctic genus Dichagyris is revised based on the survey of type specimens and relevant materials of state and private collections. D. turana (Staudinger, [1892]) stat. rev. and D. furiosa (Bang-Haas, 1912) stat. rev. are elevated to specific status and lectotypes are designated, D. forficula devota (Christoph, 1884) stat. rev. is downgraded to subspecies. The specific status of D. erubescens (Staudinger, [1892]) and D. contermina (Corti, 1930) is confirmed. The junior synonymy of D. devota eremica (Amsel, 1935) with D. forficula devota (Christoph, 1884) was constated. Seven new subspecies (D. forficula akdagestana ssp. n., D. forficula pseudoturana ssp. n., D. forficula chitralensis ssp. n., D. turana cisiliensis ssp. n., D. furiosa kugitanga ssp. n., D. furiosa griseoerythra ssp. n. and D. contermina melanographa ssp. n.) are described, with considerations on the phyletic lines and biogeography of the taxa of the D. forficula species complex. With 79 figures.
The Effect of Bone Quality on Treatment of Intertrochanteric Fractures with Helical Blade Versus Lag Screw Fixation in Cephalomedulary Nails
Authors: Chong Alexander , Schommer Jillian , Shearer Jordan , Timmer Tysen , Brown Anthony
Published: August 2023

Introduction. The specific aim of this retrospective study was to determine whether bone quality has any effect on the complication rates or overall survivorship between helical blades and lag screws in cephalomedullary nails used for intertrochanteric hip fractures.
Methods. Clinical charts and radiographic studies of patients between Jan 2012 through July 2019 were reviewed. Radiographic images (pre-, intra-, and post-operative) were reviewed to evaluate fracture fixation type, fracture reduction grade, and post-operative complications. DEXA scan results (T-score) and serum alkaline phosphatase (ALP) isoenzyme activity values were collected to evaluate patient bone quality.
Results. 303 (helical: 197, screw: 106) cases were included. Complications were found in 31 helical blade cases (16%) and 23 lag screw cases (22%). No statistically significant difference was detected when comparing complication rates to patient bone quality between these two groups. These two groups had similar one-year implant survivorship with respect to T-score, the low ALP level group, and normal ALP level group. The helical blade had higher implant survivorship compared to lag screw in five-year survival rate with respect to osteoporotic group, high ALP level group, and normal ALP level group. (Osteoporotic: 77% vs 69%, High ALP: 73% vs 67%, normal ALP: 70% vs 64%).
Conclusions. Similar complication rates were observed between helical blade and lag screw constructs in cephalomedullary femoral nails when accounting for patient bone quality. However, the bone quality had positive influence on the initial post-operative fracture reduction grade, and the five-year implant survivorship.
INVESTIGATION OF THE EFFECT OF PROCESS PARAMETERS IN CO2 LASER CUTTING OF PMMA MATERIAL BY RESPONSE SURFACE METHOD
Authors: KURT Emre , KARAÇAY Umut Efe , TUTAR Mümin
Published: August 2023

Recently, the studies on lightweighting have gained significant importance due to requirements such as energy efficiency and sustainability. Polymer materials are a group of materials that are frequently used for this purpose. This study investigated the effects of laser power, cutting speed and focal point on the kerf width, which are the most effective process parameters in laser cutting of Polymethylmethacrylate, a low-cost polymer material, using Response Surface Methodology and ANOVA. The results obtained from the data analysis show that the kerf width is seriously affected by the focal point depth as well as the speed and power.
OZON TEMAS TANKLARININ HİDROLİK VE KARIŞIM VERİMLERİNİN İYİLEŞTİRİLMESİ
Authors: KIZILASLAN Mehmet Anıl , DEMİREL Ender
Published: August 2023

İçme sularının dezenfeksiyon maliyetleri kentleşme, nüfus artışı ve yüksek enerji kullanımı nedeniyle her geçen gün artmaktadır. Ozon ile içme sularının dezenfeksiyonu ön dezenfeksiyon yöntemi olarak ülkemizde bazı içme suyu arıtma tesislerinde kullanılmakta olup Dünya’da giderek yaygınlaşmaktadır. Ülkemizde de yakın zamanda ozonla dezenfeksiyon sürecinin yaygınlaşacağı beklenmektedir. Bu çalışmada, bir içme suyu arıtma tesisinde bulunan ozon temas tankının hidrolik ve karışım verimleri sayısal benzetimler ile değerlendirilmiştir. OpenFOAM açık kaynak kodlu yazılımı kullanılarak gerçekleştirilen sayısal benzetimler ile öncelikle akım yapısı detaylı olarak incelenmiştir. Daha sonra, Üç Yarıklı Perde (ÜYP) ve Gözenekli Perde (GP) tasarımları tank içerisinde uygulanarak akım yapısındaki değişimler elde edilmiştir. Çalışmanın son bölümünde bozunmasız izleyici sayısal benzetimleri ile tankın hidrolik ve karışım verimleri Klasik Perde (KP), ÜYP ve GP tasarımları için ayrı ayrı değerlendirilerek tankın verim artışı değerlendirilmiştir.
PLASTIC JOINING METHODS: ULTRASONIC AND VIBRATION WELDING
Authors: KIYILI Onur
Published: August 2023

Plastic welding is a common method for manufacturing parts that can’t be molded and has a complex geometry such as the part that has undercuts. The process is suitable for mass production, cheap and meets automotive requirements. The process helps the zero-emission target of the automotive industry, due to the biggest obstacle of the plastic use in this sector was the moldability of the complex geometries. Most of the engine parts such as thermostat, water pump etc. can’t be molded as one piece. These engine components are manufactured by helping the plastic welding and decrease the weight of the automobile, therefore, improving fuel efficiency. Plastic welding technology has become more important especially in electrical vehicles, because metal to plastic replacement has a significant role in decreasing the weight of the vehicle. Selecting the welding method according to the polymer properties and the geometry of parts are the most important factors for the application area. All of the welding methods are basically based on the remelting of the welding surfaces of the parts and the consolidation of them under the pressure. In this paper, the vibration welding and the ultrasonic welding methods have been inspected. The most effective parameters of both processes have been discussed and shown.