bluuebunny/crossref_metadata_2025 huggingface dataset:
Swimming Sports: Parental Management In Children With Asthma
Authors: Karisman Vicki Ahmad , Nursyamsi Yusup
Published: February 2023

This study aims to determine the management of parents through physical activity, in this case, swimming, to reduce asthma symptoms. This swimming activity is collaborated with other activities such as cycling, walking and running. This research method uses Qualitative Research with one participant who is a parent of asthmatics. The instrument used is an interview, and the data was analyzed using Health Literacy Theory.   The results show that by managing health-literate parents, the program will impact reducing asthma symptoms in children
State Immunity, Between Past and Future
Authors: Popa Tache Cristina Elena
Published: February 2023

Background: State immunity, a subject rarely encountered in the East, is being brought to light more and more often lately. In the process of being detached from customary law, it has been subject to several attempts at codification. These attempts appear to have been overtaken by developments in doctrine, which demonstrates the existence of potentially delicate situations of public international law. In this context, we recall the United Nations Convention on Jurisdictional Immunities of States and their Property (New York, December 2004), which has not yet entered into force.1 In this context, we also note the initiatives for the establishment of the European Court of State Immunity contained in the European Convention on State Immunity of 1972 and its Additional Protocol, which has never been operational.2
Methods: This article aims to take stock of the status quo of the doctrine of state immunity in international law as a whole by highlighting the existing normative aspects in relation to the problems of implementation.
Results and Conclusions: The arguments and conclusions are intended to underline the importance of understanding the reality, in particular, of how this doctrine works together with its exceptions. The method of scientific introspection based on primary and secondary data from scientific journals, books, documents, expert opinions, and other publications has been used to develop this article.
CULTURAL CONTENTS IN SPEAKING MATERIALS AND ACTIVITIES FOR TENTH-GRADERS
Authors: Sholihah Nur Lailatus , Indah Rohmani Nur
Published: February 2023

EFL textbooks should be valued based on their visual illustration and based on their cultural background and goals of EFL learning. The study aimed to report the results of a textbook analysis to identify which type of culture and what themes of culture were introduced in the tenth graders of Indonesian senior high school. Theory of cultures proposed by Cortazzi Jin (1999) and Chen Lee (2004) were adapted for examining specific aspects of culture under formal culture and aspects of life culture. The analysis revealed that the percentage of source culture (45,7%) and unidentified culture (42,9%) is the same in the textbook. The textbook was dominated by source culture content among identified cultural content, while international culture (5,7%) and target culture (5,7%) contained a small percentage. It was also found out that among the 19 cultural themes under formal culture and aspects of life culture, the researcher found four themes such as lifestyle, gestures, and holiday under aspects of life culture and only history under formal culture. The predominant theme was aspects of life culture of lifestyle.
EFL STUDENTS’ PERCEPTION TOWARD ONLINE LEARNING DURING COVID 19
Authors: Yana Dewi , Putri Aulia
Published: February 2023

During the Covid 19 Pandemic, lectures were carried out totally via online learning. This study aims at describing the EFL students’ perception on the issue. This study applied a descriptive method and involved 102 students of the English Education Study Program- Riau Kepulauan University. The questionnaire was in 5 Likert scale and open questions which was modified from three components of Information Technology Innovation-instrument by Moore and Benbasat namely relative advantage, ease of use, and compatibility. It also was settled up to get information on challenge, obstacles, and students’ negative opinion toward the online-learning. The data was taken at the end of even semester (July) on academic year 2019/2020, and it was distributed by sending online survey to the year 1 to 4 of English Education Study Program of UNRIKA. In analyzing the data, it was computed to get the frequencies and percentages. The results are displayed in the form of chart and tables, and it is found that students’ perception can be considered as the important factor in applying the online learning particularly in the Covid 19 pandemic era.
IDEATION TAXONOMIC RELATION OF HATA PANGUPA GRADUATION CEREMONY IN PADANGSIDIMPUAN
Authors: Nasution Mutia
Published: February 2023

This study deals with the types of taxonomic of Hata Pangupa graduation Ceremony in Padangsidimpuan. The objectives of this study are to describe the types of taxonomic relation occrued in Hata Pangupa graduation Ceremony in Padangsidimpuan, to analyze the relation of taxonomic relation in Hata Pangupa graduation Ceremony in Padangsidimpuan, to explain out the reasons why the taxonomic relations describe in the way they are. It presented a qualitative data analysis. The source of the data was taken from the video recorded. The data analysis found out the findings that four types of taxonomic relation were used in Hata Pangupa graduation Ceremony in Padangsidimpuan. The kinds that were used are repetition, synonym, contrast: series (opposition), class: class-member and co-class. Whereas, the contrast: series (cycles), and part: co-part did not use by Mora, Kahanggi and Anak Boru in Hata Pangupa Wedding Ceremony in Tapanuli Selatan. The process were showed the reference chains, they are personal and demonstrative. Hata Pangupa has an institution spoken by specialist speakers and it is part of social interaction, religion and traditional custom.
Developing of Audio Visual Text Module on Congratulation and Compliment Expressions
Authors: Putri Febrika Meylani Irwanda , Ashari Erwin , Pohan Albert Efendi , Edi Warno
Published: February 2023

Learning media is an important component in learning. One of the media that can be used is audio visual media. The aim of this study was to develop a feasible Audio Visual Text Module on Congratulation and Compliment Expressions as learning media.This reasearch was conducted at Karang Taruna RW 17 English Course Sei Langkai, Batam, and research and development (R&D)Hannafin and Peck modelwas used. The instrument used to collect data in this research wasquestionnaireswhich validated by material and media experts, then shared to tutors and studentsusing a Likert scale. Product trial obtained 77.02% for students response and it was categorized as ‘agree’ category. Meanwhile it obtained 76.67% for tutor rensponse and it was categorized as ‘agree’ category.Usage trial obtained 87.07% for students response and it was categorized as ‘strongly agree’ category. Meanwhile it obtained 88.66 for tutor rensponse and it was categorized as ‘strongly agree’ category. The products of this research are module and audio visual (MP4) about Congratulating and Compliment Expressions, and both are neccessary to be used as learning media.
ESP: STUDENTS’ PERCEPTIONS IN USING ROLE PLAY STRATEGY TO IMPROVE SPEAKING ABILITY
Authors: Safitri Raihan , Purba Nafa Nazwa
Published: February 2023

Abstract      Speaking ability is a one-of-a-kind aspect of language development that is very important to be instilled from an early age. The purpose of this research is to examine ESP based on the students' perceptions of using role-play strategies to improve speaking skills. This article discusses how students can improve their speaking skills in ESP. ESP remains for English for Specific Purpose, and it is a component of English as a foreign language or second language. Typically entails teaching English to students or people who have already worked, with emphasis on the vocabulary and skills they require. Role play is a motion consultation program that includes elements of fun as well as a system and purpose. The ability to foster optimism and a sense of togetherness through active learning is one of the benefits of using the role-play method. Most students struggle with speaking when learning a language, particularly English. Problem speaking is typically caused by difficulties involved in expressing things verbally, a restricted vocabulary, restricted grammar skills that make it difficult to communicate with the right rules, and a limited power to pronounce words (pronunciation), making it difficult to the pronunciation of words that are communicated properly right.
Bioeconomia na Amazônia: importância da matéria orgânica do solo para a manutenção dos sistemas produtivos
Authors: Frare Julio Cesar Vieira , Martins Gabriel Caixeta , Freitas Ludmila de , Oliveira Ivanildo Amorim de , Ramos Silvio
Published: February 2023

Na Amazônia, as condições naturais de baixa fertilidade e elevada acidez dos solos impõem grandes desafios para a manutenção da produção agrícola. Nessas circunstâncias, a matéria orgânica é essencial para a qualidade dos solos, influenciando seus atributos físicos, químicos e biológicos. O aporte constante de biomassa em uma floresta promove a ciclagem de nutrientes, disponibilizando, em parte, os nutrientes necessários para o desenvolvimento das plantas. O mesmo não ocorre na agropecuária, em que a remoção da cobertura vegetal e a falta de manejo adequado afetam consideravelmente a sustentabilidade dos sistemas de produção. O objetivo deste trabalho foi, portanto, ressaltar a importância da matéria orgânica para a conservação dos solos da Amazônia, destacando os impactos do desmatamento sobre a qualidade do solo e aspectos relevantes para a sua recuperação. Para isso, foram consultados artigos científicos indexados em bases de dados online nos últimos quinze anos, além de livros, dissertações, teses e publicações técnicas. A implantação de sistemas agroflorestais destaca-se como opção para a recuperação de áreas degradadas na Amazônia, ainda que existam diversos desafios para o seu uso, como a falta de informações acerca de quais espécies utilizar em cada situação. A recuperação de solos degradados exige projetos específicos que levem em conta, entre outros aspectos, o uso de espécies-chave para garantir o êxito deste processo, sendo necessários estudos que avaliem o desempenho das espécies melhor adaptadas às diversas condições de clima e solo das áreas a serem recuperadas.
O uso das tecnologias educativas na educação em saúde sexual com adolescentes
Authors: Costa Aniarly Bezerra Silva , Jesus Junior Andre Macedo de , Oliveira Camilla Araújo , Pereira Jénifer Valesca Oliveira , Santos Marks Passos
Published: February 2023

Objetivo: identificar as tecnologias educativas utilizadas na educação em saúde sexual com adolescentes. Método: trata-se de um estudo do tipo revisão integrativa da literatura, realizada entre os meses de maio e junho de 2021, nas bases de dados, bibliotecas e buscador acadêmico, com os seguintes descritores: “Educação em Saúde”, “Tecnologia Educativa”, "Saúde Sexual", "Adolescente" utilizando o booleano “and”. Resultados: foram encontrados 72 estudos e com o emprego dos critérios de elegibilidade foram descartados 62 artigos, restando 10 artigos. As tecnologias encontradas com as buscas foram os jogos educativos, as multimídias e as redes sociais, ferramentas essas que demonstram efetivas com relação a melhoria no ganho de conhecimento sobre infecções sexualmente transmissíveis, gravidez na adolescência, uso de preservativos e sexualidade. Conclusão: as tecnologias comumente utilizadas na educação em saúde com adolescentes são os jogos educativos, as multimídias e as redes sociais, ambientes considerados eficazes no processo de aprendizagem de diversos temas.
Aspectos psicológicos de indivíduos bariátricos relacionados ao reganho de peso durante a pandemia por COVID-19
Authors: Mendes Jogilmira Macedo Silva , Lotufo Neto Francisco , Santos Maria Cecília Queiroga dos , Lucena Debora de Souza , Rocha Rossana Maria da Silva , Fernandes Rosa Virginia Rocha , Rodrigues Mabel Osório , Morais Gilvânia Smith da Nóbrega , Barbosa Khivia Kiss da Silva
Published: February 2023

Introdução: Atualmente a cirurgia bariátrica e ou metabólica são muito aceitas, pois é o único tratamento altamente disponível para cura significativa das comorbidades associadas à obesidade. Objetivo: O presente estudo objetivou avaliar os aspectos psicológicos de indivíduos bariátricos e sua relação com o reganho de peso tardio durante a pandemia do COVID-19. Método: Foi realizada uma investigação exploratória e descritiva, com abordagem quantitativa, sendo incluídos indivíduos maiores de 18 anos e que tenham vivenciado o pós-operatório há mais de 60 meses. Resultados: verificou-se uma maior incidência do sexo feminino (71,7%,) com idade média de 40 anos (±7,6) e com 3 grau completo (78%). Em relação ao reganho de peso durante a pandemia, (69,0%) relataram que teve reganho. Quando questionados sob a presença de transtornos psicológicos, 52,2% relataram ter apresentado algum transtorno durante a pandemia. Destes, o mais prevalente foi a ansiedade (51,3%), seguido da compulsão alimentar (19,5%), depressão (16,8%) e consumo de bebida alcoólica (34,5%). Conclusão: Tendo em vista a influência da pandemia COVID-19 no reganho de peso pós-cirurgia bariátrica, observa-se que a população mais atingida foram as mulheres com renda familiar e econômica estáveis, porém acometidas por transtornos psicológicos que se agravaram em decorrência do período pandêmico.
Doença de Crohn: aspectos integrativos do diagnóstico ao tratamento
Authors: Dal Lin Fernando Tonholi , Mazarroto Edson José , Gregório Paulo Cézar
Published: February 2023

Objetivo: Identificar os aspectos atuais ao longo do curso da doença de Crohn (DC), desde o diagnóstico, tratamentos farmacológicos, cirúrgicos e recomendações nutricionais. Método: Este estudo é uma revisão integrativa da literatura que se respalda na busca de artigos em bases de dados, Pub Med, Lilacs, Scielo, periódicos e sites, com os seguintes descritores em “Crohn’s disease”, “Crohn’s Disease treatment”, “Inflammatory Bowel Diseases”, “Physiopathology of Inflammation”, utilizando artigos de pesquisas originais e revisões entre anos de 2014 a 2022. Esse levantamento bibliográfico foi realizado no período de 01/03/2022 a 20/10/2022. Resultados: De um total de 1850 artigos encontrados, foram selecionados 84 artigos que se enquadravam no escopo da revisão. Discussão: Atualmente todo o curso da DC se mostra bem completa, desde seu diagnóstico ao tratamento que pode envolver medicamentos biológicos, além da necessidade de uma dieta adequada a fim de se evitar desnutrição do paciente. Conclusão: Visto toda a complexidade englobada na DC, é primordial a atuação de equipe multidisciplinar na conduta do tratamento do paciente, o que pode contribuir imensamente para a qualidade de vida e adesão ao tratamento pelo paciente.
Peningkatan kapasitas manajerial masjid bagi pengurus dewan kemakmuran masjid
Authors: Khaeriyah Ery , Ghofur Muhammad Ikhsan , Khikmawati Nurlaili
Published: February 2023

Masjid pada masa sejarahnya berfungsi selain sebagai tempat ibadah, tetapi juga berfungsi sebagai pusat peradaban masyarakat. Namun, pada masa sekarang fungsi masjid mengalami penyusutan yaitu hanya sebagai tempat ibadah saja. melalui kegiatan pengabdian ini diharapkan mampu mengembalikan fungsi masjid sesuai dengan kapasitas dan potensi yang dimiliki. Metode yang digunakan adalah metode PAR dengan tahap pelaksanaan diantaranya adalah observasi, pemetaan potensi, pelaporan hasil pemetaan dengan menggunakan metode pelatihan, setelah diadakan pelatihan, kemudian dilaksanakan pendampingan hingga terbentuknya profil masjid yang sesuai dengan potensi dan aset masjid. Temuan pengabdian yang diperoleh adalah adanya permasalahan mengenai kepengurusan yang belum testruktur.. Setelah penemuan masalah, kemudian dilaksanakan kegiatan pelatihan sesuai dengan kebutuhan. Pelatihan tersebut berisi tentang fiqih dan sejarah masjid, serta manajerial masjid. Pada saat pelatihan, pengurus DKM juga dibimbing untuk bisa mengidentifikasi potensi dan aset yang dimiliki masjid. Kesimpulan yang dihasilkan pengurus menjadi lebih mengetahui pengelolaan masjid yang terstruktur. Adapun yang kegiatan yang bisa dilakukan selanjutnya adalah pendampingan kepengurusan dan profil masjid serta kegiatan insindental berupa pendampingan penentuan arah kiblat.
Symptoms and Quality of Life in Gastroenteropancreatic Neuroendocrine Tumours
Authors: Kaupp-Roberts Sebastian , Srirajaskanthan Rajaventhan , Ramage John K.
Published: February 2023

Gastroenteropancreatic neuroendocrine tumours (GEP-NETs) have the ability to induce symptoms either by their direct mass effect on local tissues (symptoms such as pain, bowel obstruction, obstructive jaundice, and bleeding), or by the ectopic secretion of bioactive compounds. GEP-NETs are frequently associated with significant diagnostic delays, and metastatic disease is often a feature at initial presentation. Quality of life (QoL) research in GEP-NETs is a comparatively new field, with a disease- specific QoL questionnaire, the QLQ-GINET21, having been fully validated only as recently as 2013. It has been reliably demonstrated to date that diarrhoea, fatigue, and flushing are the symptoms provoking the greatest decline in patient QoL. Furthermore, depression is highly prevalent in the GEP-NET population. This paper reviews current understanding and potential future developments in this field.
Electrophysiological Analyses of the Plasmalemma Reactions of Nitellopsis obtusa Cells Against Selective Modification of Its Structural and Functional Components
Authors: Makhmudova Sh.
Published: February 2023

The kinetics of changes in the membrane potential (φ), resistance (Rm) and membrane capacity (Cm) were compared with the modification of the structural and functional components of the plasmalemma of Nitellopsis obtusa cells. For the plasmalemma electrogenic pump, the following are established: short-circuit current 0.09 A/m2, internal resistance 4 Ohm×m2, electromotive force — 360 mV. The analyses of the kinetics of measuring φ, Rm, Cm during the modification of the structural and functional components of the plasmalemma revealed that the electrical capacity is an indicator of its lipid phase. The totality of established facts about the effect of standard modifiers on the main electrophysiological parameters of the plasmalemma indicates the presence of an organic relationship between the functional activity and the phase state of the lipid environment of the functional groups of the plasmalemma.
The Impact of Climate Change on the Economy Damage and Adaptation Ways
Authors: Dadashev M.
Published: February 2023

The article is dedicated to recent climate changes, their consequences, damage to the economy, and ways to adapt to climate changes. The article also included information about global warming. It is revealed that the number of hot spring-summer days in Azerbaijan periodically increases, and the number of cold autumn-winter days relatively decreases. In plain areas of the country — in areas where agriculture is more developed, drought prevails. Average annual temperature on plains and foothills is higher than in mountain areas. The eternal ice and snow cover, located on the peaks of the mountains of the Greater and Lesser Caucasus, are melting and their area is shrinking.
Hazelnuts Varieties and Forms Performance in the Guba-Khachmaz Economic Region (Azerbaijan)
Authors: Sadygov A. , Rashidov B.
Published: February 2023

The article provides information on the indicators of economic productivity of the form and varieties of hazelnuts, the name of varieties and forms, by years of yield, cost, average yield, product cost per hectare, net income, profitability and economic evaluation compared with varieties. The research work was carried out on 22 varieties and forms of hazelnuts, and to compare the productivity indicators of varieties and forms, it was carried out using the Ata-baba variety, which was taken as a control variety. Research work was carried out on varieties and forms of hazelnut Ata-baba, G1-Gz1, G3-U1, Gu1-A1, G5-Gk1, G6-Chg1, Yagly hazelnut, Zakatala, Zakatala-9, X4-Yh1, Sh1-A1, Sh2-A2, Sh3-H1, Sh4-H2, H1-Az1, H2-Az2, X3-N1, Ashrafy, Shish hazelnut, H5-Hu1, forest hazelnut. The study compares the economic indicators of the productivity of varieties and forms using the Ata-Baba variety, which is taken as a control variety. The cost of growing 1 hectare of hazelnuts is 1114-1620 manats, and the cost of one centner of products ranges from 58.5-110.6 manats. The profitability of research varieties ranged from 138-395%. From varieties and forms G3-U1(395%), Sh2-A2 (391%), H4-Yh1(382%) G5-Gk1 (355%), Yagli hazelnuts (322%), G1-Gz1(320%), Ashrafy (265%) were high compared to the control Ata Baba (241%).
Review of the Quality Problems of Additional Education of Doctors and the Main Directions for Their Solution
Authors: Niyazova S.
Published: February 2023

Experience with the introduction of a competency-oriented supplementary education program, as well as a dual education system, in the educational process of the Kyrgyz Republic shows that the study of theory in unity with practice is the most an effective method of training, as it reveals and actively shapes the social and professional qualities of doctors, allowing faster and more successful adaptation to changing working conditions.
Psychologism in The Long March Section of The Epic of Manas
Authors: Tolubaeva Ch. , Zhumashova N.
Published: February 2023

The article deals with some issues related to psychologism The Long March in section of The Epic of Manas. In this section of The Epic of Manas there are often monologues, speeches of characters, dialogues, psychological descriptions, which are considered as actively used artistic means of expressing psychologism. In addition, such types of monologues as dying instruction and lamentation are noted. Examples of the description of the psychological states of the characters were also given. In particular, a separate fragment was considered and analyzed in connection with the issues of psychologism, where Manas mourned his best knights who fell in battle. Also, to illustrate the tragedy, drama, psychologism, excerpts from the episodes describing the death of Manas are given, and other excerpts from the monologues that are found in this section of the epic are analyzed. Among them, special importance was attached to the monologue of Almanbet, which is considered a tragic image in The Epic of Manas.
Creation of a geospatial database of particularly valuable productive agricultural land taking into account geodetic data in order to provide land monitoring
Authors:   Saint Petersburg Mining University, Kolesnik O. A. , Demidova P. M. ,   Saint Petersburg Mining University, Sannikova A. P. ,   Saint Petersburg Mining University
Published: February 2023

A geospatial database is the best way to systematize and present attributive and spatial data. Currently, there is no single geospatial database of particularly valuable agricultural land for the entire territory of the country. Most of the land plots belonging to such lands have not yet been registered in the Unified State Register of Real Estate or do not have the coordinates of the borders and, respectively, are not marked on the Public Cadastral Map. Monitoring of such lands is not carried out properly, there is no information about the composition and quality of such lands. But the primary issue when creating a geospatial database is the source data – the basis of the object's coordinate reference. The article ana-lyzes the normative legal acts on the research topic, provides an overview of geoinformation systems and geoinformation resources in the field of agriculture and for comparison in the field of forestry. The creation of a geospatial database of especially valuable agricultural lands is considered on the example of the Volosovsky district of the Leningrad region. The insufficiency (incompleteness) of the coordinated boundaries of the lands was noted. The geospatial database of especially valuable agricultural lands will allow you to have a complete picture of the quantity, area, composition, condition and use of especially valuable agricultural lands, for which it is important to keep records and monitor in order to preserve, protect and develop them.
Study of the state of the environment in the area of oil production using space images
Authors:   Siberian State University of Geosystems and Technologies, Gordienko A. S. , Tkach A. V. ,   Siberian State University of Geosystems and Technologies
Published: February 2023

The article presents the results of the research analyzing the state of the environment in the area of oil production based on space images. The problems of identifying the negative impact of oil on the components of the natural environment are described. The results of the experiments focusing on the influence of oil spills on the state of soils, hydrographic objects and vegetation are presented. The index images were calculated and the index values in the contaminated area were analyzed. The suppression of vegetation in the zone affected by petroleum products, soil restoration after an extensive oil spill, and river pollution were revealed. The data obtained as a result of experiments are confirmed by information from open sources. The conclusion about the effectiveness of the use of index images of the research analyzing the state of the environment in the area of oil production based on space images is made. Images obtained in the four main spectral ranges (R, G, B, NIR) allow you to successfully solve most of the problems considered in this article.
Taking risks
Authors: Von Kotze Astrid , Walters Shirley
Published: February 2023

The climate catastrophe is a clarion call to humanity to change how we live. How do radical popular educators respond to this call? We ‘join the dots’ using climate justice, ecofeminism and our own insights from our engaged activist scholarship as theoretical positions to explore this question.  Dominant Western worldviews which separate humans from other life forms contribute to ecological degradation.  For climate justice, this hard-wired worldview needs to be disrupted. Drawing on multiple examples from Africa, we conclude that ways to do this require the foregrounding of cognitive justice which includes recognising the validity of multiple knowledges, learning from others and supporting communities’ in their struggles for reparation, reclamation and conservation of their land. These actions can be amplified in engagements which disrupt the unsustainable behaviour and policies of the wealthy. We argue that radical popular education in these times is climate just and ecofeminist.
Инстинкт гармонии смыслов. Информационная теория этноса: аспекты и интерпретации (К 90-летию Сергея Александровича Арутюнова)
Authors:   N. N. Miklukho-Maklay Institute of Ethnology and Anthropology, RAS, Банников К. Л.
Published: February 2023

Книга, посвященная 90-летию выдающегося российского этнографа и антрополога С. А. Арутюнова представляет собой жизнеописание, научную биографию, список трудов, а также размышления автора по поводу синхронизации социокультурогенных информационных потоков, одного из аспектов его теории этноса и цивилизаций, применительно к интерпретации современного глобального кумулятивного кризиса. Современные информационные мультимедийные технологии обеспечивают преобладание синхронных коммуникаций над диахронными, аудиовизуальных каналов ретрансляции культурно-значимой информации над текстом, эмоционально-чувственного восприятия над рационально-аналитическим. Глобальная и тотальная синхронизация информации обеспечивает цивилизации качественный переход в новую фазу, в которой культура, социальность, сама природа человека подчинена технологиям. Автор ставит вопрос – в чем состоит феномен информации вообще, отвечая на который, обращается к когнитивной антропологии, работающей с фундаментальными структурами сознания, образные проявления которых открываются в мифологии. В работе рассматривается современный кризис глобальной цивилизационной модели с точки зрения закономерностей развития информационных систем, вступающих в фазу деградации в точке перехода от вектора структурности к фазе монадности, в состояние абсолютной синхронизации замыкаемых на себя энергий, с происшествием в минимальную единицу времени всех возможных событий системы, завершающее ее, системы, историю.
Туркменские традиционные ремёсла. Металлообрабатывающие и деревообрабатывающие производства
Authors: Dolgov A. A.
Published: February 2023

The book is the first ethnographic study on the development of traditional male craft industries in 19th-20th centuries Turkmenistan: blacksmithing, coppersmithing, jewelry, construction and carpentry, carpentry, and turning. The author details specific features of artisans’ fabrication activities, describes and analyzes their products, and classifies products by craft type and purpose, including technical and technological processes for certain types and groups of products, tools, and devices. The book determines the stages of Turkmen’s traditional handicraft evolution in the era preceding the modernization of society, economy, and culture. It considers the views and assessments of 19thcentury European authors. The work specifies Turkmen traditional crafts, information about the places of their distribution, and several methods used in some types of these crafts. Based on archival documents and publications of previous years, the author outlines the general state of Turkmen handicraft production. The book draws specific attention to the development, distribution, and correlation of metalworking and woodworking industries in different districts and regions of Turkmenistan. The paper illustrates production conditions, activities of artisans, workshops, devices, and tools of various crafts, hard and soft materials manufacturing processes, and technical and technological methods used to manufacture different products in traditional handicraft industries. The reader will also get acquainted with customs and rituals related to specific traditional crafts.
Técnicas reposicionamiento canalicular con mayor efectividad en el vértigo posicional paroxístico benigno
Authors: Porras Huertas Liliana , Díaz Barbosa Miladis del Carmen
Published: February 2023

El Vértigo Posicional Paroxístico Benigno es uno de los diagnósticos más comunes y consultados en la práctica  clínica de patologías de vértigo, por lo tanto, el presente artículo  tiene como finalidad, describir las técnicas de reposicionamiento canalicular más utilizadas por Audiólogos expertos en rehabilitación vestibular específicamente para  los conductos semicirculares de mayor prevalencia que se ven afectados en esta patología, los cuales son; el conducto semicircular posterior y el conducto semicircular horizontal, en contraste con las técnicas de mayor efectividad reportadas en la literatura. Lo anterior, sustentado en la aplicación de una encuesta, y, revisión de literatura especializada a través de una metodología con enfoque cualitativo y alcance descriptivo, se encuestó a doce Audiólogos especialistas en rehabilitación vestibular mediante la técnica bola de nieve.
                En cuanto a la revisión de literatura científica se tuvo en cuenta publicaciones de los últimos cinco años de bases de datos especializadas, seleccionando quince artículos de acuerdo con los criterios de inclusión, obteniendo como resultado que actualmente existe correspondencia entre las técnicas recomendadas en la literatura y las aplicadas en la práctica audiológica.
Assisted probe guidance in cardiac ultrasound: A review
Authors: Ferraz Sofia , Coimbra Miguel , Pedrosa João
Published: February 2023

Echocardiography is the most frequently used imaging modality in cardiology. However, its acquisition is affected by inter-observer variability and largely dependent on the operator’s experience. In this context, artificial intelligence techniques could reduce these variabilities and provide a user independent system. In recent years, machine learning (ML) algorithms have been used in echocardiography to automate echocardiographic acquisition. This review focuses on the state-of-the-art studies that use ML to automate tasks regarding the acquisition of echocardiograms, including quality assessment (QA), recognition of cardiac views and assisted probe guidance during the scanning process. The results indicate that performance of automated acquisition was overall good, but most studies lack variability in their datasets. From our comprehensive review, we believe automated acquisition has the potential not only to improve accuracy of diagnosis, but also help novice operators build expertise and facilitate point of care healthcare in medically underserved areas.
Design and evaluation of a multi-sensory representation of scientific data
Authors: Varano Stefania , Zanella Anita
Published: February 2023

Introduction

Modern sciences and Astrophysics in particular study objects and phenomena not visible in physical terms, that is they cannot be investigated with the eyes or analogous optical systems. Nevertheless, they make intensive use of visual representations, showing data in a figurative way, using lights, shadows, colors, and shapes familiar to the user and aesthetically pleasant. Besides being inaccessible for Blind and Visually Impaired (BVI) users, such figurative visual representation can lead to misunderstandings about the real nature of the represented object, physically invisible, particularly if the representation code is not declared. In this work we argue that multi-sensory representations clearly arbitrary, i.e., that do not aim to imitate reality, are a valid choice for an effective learning and understanding of astronomical science and for an effective meaning-making process for all. The presence of a cognitively challenging code of representation can make the fruition more conscious and attentive, leading to a deeper understanding of the represented reality, also mirroring the search for relevant information proper of basic research. In an equity perspective, multi-sensory representations also create an effective common ground for inclusion among people with diverse abilities, skills, and learning styles, in the framework of Universal Design for Learning.

Methods

In order to investigate our hypothesis we designed two mono-sensory representation (one only haptic and the other only acoustic) and tested them in individual and group workshops with both sighted and BVI users. We then used our results to guide the design of a multi-sensory representation of non-visible astronomical data including visual, acoustic, and haptic stimuli. We tested this representation as well, in order to refine and propose it to the public.

Results

The result is the exhibit “Sense the Universe,” to be used for outreach and education. “Sense the Universe” was part of a museum exhibition attended both by sighted and BVI users, where we collected feedback about the final outcome of our work.

Discussion

Our findings suggest the validity of multi-sensory representations for a truly and effective engagement in scientific learning, both in terms of intelligibility and persistence of scientific contents and of a more equal access to scientific culture.
Optimal storage for solar energy self-sufficiency
Authors: Carlsson Anders E. , Redner S.
Published: February 2023

We determine the energy storage needed to achieve self sufficiency to a given reliability as a function of excess capacity in a combined solar-energy generation and storage system. Based on 40 years of solar-energy data for the St. Louis region, we formulate a statistical model that we use to generate synthetic insolation data over millions of years. We use these data to monitor the energy depletion in the storage system near the winter solstice. From this information, we develop explicit formulas for the required storage and the nature of cost-optimized system configurations as a function of reliability and the excess generation capacity. Minimizing the cost of the combined generation and storage system gives the optimal mix of these two constituents. For an annual failure rate of less than 3%, it is sufficient to have a solar generation capacity that slightly exceeds the daily electrical load at the winter solstice, together with a few days of storage.
Exosome-derived CIRP: An amplifier of inflammatory diseases
Authors: Han Jingrun , Zhang Yibo , Ge Peng , Dakal Tikam Chand , Wen Haiyun , Tang Shuangfeng , Luo Yalan , Yang Qi , Hua Bianca , Zhang Guixin , Chen Hailong , Xu Caiming
Published: February 2023

Cold-inducible RNA-binding protein (CIRP) is an intracellular stress-response protein and a type of damage-associated molecular pattern (DAMP) that responds to various stress stimulus by altering its expression and mRNA stability. Upon exposure to ultraviolet (UV) light or low temperature, CIRP get translocated from the nucleus to the cytoplasm through methylation modification and stored in stress granules (SG). During exosome biogenesis, which involves formation of endosomes from the cell membrane through endocytosis, CIRP also gets packaged within the endosomes along with DNA, and RNA and other proteins. Subsequently, intraluminal vesicles (ILVs) are formed following the inward budding of the endosomal membrane, turning the endosomes into multi-vesicle bodies (MVBs). Finally, the MVBs fuse with the cell membrane to form exosomes. As a result, CIRP can also be secreted out of cells through the lysosomal pathway as Extracellular CIRP (eCIRP). Extracellular CIRP (eCIRP) is implicated in various conditions, including sepsis, ischemia-reperfusion damage, lung injury, and neuroinflammation, through the release of exosomes. In addition, CIRP interacts with TLR4, TREM-1, and IL-6R, and therefore are involved in triggering immune and inflammatory responses. Accordingly, eCIRP has been studied as potential novel targets for disease therapy. C23 and M3, polypeptides that oppose eCIRP binding to its receptors, are beneficial in numerous inflammatory illnesses. Some natural molecules such as Luteolin and Emodin can also antagonize CIRP, which play roles similar to C23 in inflammatory responses and inhibit macrophage-mediated inflammation. This review aims to provide a better understanding on CIRP translocation and secretion from the nucleus to the extracellular space and the mechanisms and inhibitory roles of eCIRP in diverse inflammatory illnesses.
Role of chemokine-like factor 1 as an inflammatory marker in diseases
Authors: Li Yutong , Yu Haiyang , Feng Juan
Published: February 2023

Immunoinflammatory mechanisms have been incrementally found to be involved in the pathogenesis of multiple diseases, with chemokines being the main drivers of immune cell infiltration in the inflammatory response. Chemokine-like factor 1 (CKLF1), a novel chemokine, is highly expressed in the human peripheral blood leukocytes and exerts broad-spectrum chemotactic and pro-proliferative effects by activating multiple downstream signaling pathways upon binding to its functional receptors. Furthermore, the relationship between CKLF1 overexpression and various systemic diseases has been demonstrated in both in vivo and in vitro experiments. In this context, it is promising that clarifying the downstream mechanism of CKLF1 and identifying its upstream regulatory sites can yield new strategies for targeted therapeutics of immunoinflammatory diseases.
Regulation of innate immune signaling by IRAK proteins
Authors: Pereira Milton , Gazzinelli Ricardo T.
Published: February 2023

The Toll-like receptors (TLRs) and interleukin-1 receptors (IL-1R) families are of paramount importance in coordinating the early immune response to pathogens. Signaling via most TLRs and IL-1Rs is mediated by the protein myeloid differentiation primary-response protein 88 (MyD88). This signaling adaptor forms the scaffold of the myddosome, a molecular platform that employs IL-1R-associated kinase (IRAK) proteins as main players for transducing signals. These kinases are essential in controlling gene transcription by regulating myddosome assembly, stability, activity and disassembly. Additionally, IRAKs play key roles in other biologically relevant responses such as inflammasome formation and immunometabolism. Here, we summarize some of the key aspects of IRAK biology in innate immunity.
Review: Mechanisms and perspective treatment of radioresistance in non-small cell lung cancer
Authors: Zhou Ting , Zhang Li-Ying , He Jian-Zheng , Miao Zhi-Ming , Li Yang-Yang , Zhang Yi-Ming , Liu Zhi-Wei , Zhang Shang-Zu , Chen Yan , Zhou Gu-Cheng , Liu Yong-Qi
Published: February 2023

Radiotherapy is the major treatment of non-small cell lung cancer (NSCLC). The radioresistance and toxicity are the main obstacles that leading to therapeutic failure and poor prognosis. Oncogenic mutation, cancer stem cells (CSCs), tumor hypoxia, DNA damage repair, epithelial-mesenchymal transition (EMT), and tumor microenvironment (TME) may dominate the occurrence of radioresistance at different stages of radiotherapy. Chemotherapy drugs, targeted drugs, and immune checkpoint inhibitors are combined with radiotherapy to treat NSCLC to improve the efficacy. This article reviews the potential mechanism of radioresistance in NSCLC, and discusses the current drug research to overcome radioresistance and the advantages of Traditional Chinese medicine (TCM) in improving the efficacy and reducing the toxicity of radiotherapy.
Urgent assessment needed to evaluate potential impacts on cetaceans from deep seabed mining
Authors: Thompson Kirsten F. , Miller Kathryn A. , Wacker Jake , Derville Solène , Laing Christopher , Santillo David , Johnston Paul
Published: February 2023

Deep seabed mining operations, if permitted, could present significant risks to ocean ecosystems. Disturbance on any scale is likely to be long lasting and irreversible. Scant research to date has examined the impact that deep sea minerals extraction would have on cetaceans. The Clarion-Clipperton Zone (CCZ) is of particular interest to mining companies aiming to exploit polymetallic nodules. The CCZ, with an average depth of 5,500 m and an area of approximately 11,650,000 km2, is a habitat for cetaceans including baleen (mysticetes) and toothed whales (odontocetes). Of particular concern is anthropogenic noise. If permitted, commercial-scale mining is expected to operate 24-hours a day, at varying depths. The sounds produced from mining operations, including from remotely operated vehicles on the seafloor, overlap with the frequencies at which cetaceans communicate, which can cause auditory masking and behavior change in marine mammals. Cetaceans are already facing numerous stressors, including climate change, and many species are still recovering from centuries of exploitation. We argue the need for urgent research to assess more fully the potential impact of deep seabed mining on cetaceans.
Vitamin D regulates ion regulation by affecting the ionocyte differentiation in zebrafish (Danio rerio) larvae
Authors: Lin Chia-Hao , Chang Hung-Chi , Liu Sian-Tai , Hu Huei-Jyun
Published: February 2023

Freshwater teleosts frequently face the stress of varied ion and pH levels; therefore, they have developed related defense mechanisms to maintain the homeostasis of body-fluid ion and acid-base balance. The different subtypes of ionocytes expressed in the branchial epithelium of adult fish or the skin of larvae are the major sites for fish ion regulation. 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3), the bioactive form of vitamin D, is a steroid hormone that is involved in the regulation of Ca2+ uptake and acid secretion in teleosts. Our results revealed that 1α,25(OH)2D3 levels were not changed in zebrafish larvae upon exposure to low Na+ freshwater compared to normal freshwater. In contrast, 1α,25(OH)2D3 levels were substantially higher in fish exposed to acidic and low Ca2+ freshwater than in those exposed to normal freshwater. Some hormones regulate ion regulation and acid secretion by modulating ionocyte differentiation and/or proliferation in teleosts; however, the role of vitamin D in this process is unclear. Zebrafish larvae were used as a model in the present study to explore the effect of vitamin D on ionocyte proliferation and/or differentiation. The present study indicated that 1α,25(OH)2D3 treatment increased the number of foxi3a-positive cells, ionocyte progenitors, and mature ionocytes. However, the number of P63-positive epidermal stem cells did not change in the zebrafish larvae treated with 1α,25(OH)2D3. These results revealed that vitamin D exerts a positive effect on the number of ionocytes by increasing the differentiation of ionocytes. Increased ionocyte differentiation by vitamin D is suggested to elevate the capacity of ion regulation and acid secretion in zebrafish to cope with external stress. The present findings indicate the role of vitamin D in the regulation of ionocyte differentiation and provide new insights into the mechanisms of stress adaptation of fish.
Primary postpartum hemorrhage and associated factors among delivering women in Gedeo Zone, Southern Ethiopia
Authors: Zenebe Getachew Assefa , Zenebe Wagaye Alemu , Ewunie Temesgen Muche , Dires Selamawit
Published: February 2023

Introduction

Primary postpartum hemorrhage is still the main cause of maternal death worldwide, especially in low-resource nations like Ethiopia where there are insufficient healthcare facilities and a shortage of skilled medical personnel. Data on the prevalence of primary postpartum hemorrhage in the study population are scarce or non-existent.

Objective

The aim of this study was to assess the prevalence of primary postpartum hemorrhage and its associated factors among delivering women in Gedeo Zone, Southern Ethiopia, in 2021.

Methods

A facility-based cross-sectional study was carried out from January 1 to March 30, 2021, in public health facilities in the Gedeo Zone. A randomly selected 577 participants were involved in the study. Data were gathered using an interview-administered, pre-tested, structured questionnaire. The gathered information was imported into Epi Info 3.5.1 and analyzed with SPSS 23. Descriptive data was presented using tables and graphs. A logistic regression model was fitted. A bivariable and multivariable logistic regression model was computed to identify the presence and strength of association. To run multivariable logistic regression analyses, variables with P-values of <0.2 were used. The odds ratio, a 95% confidence interval (CI), and a P-value of <0.05 were used to identify variables that were associated with primary postpartum hemorrhage.

Results

The magnitude of primary postpartum hemorrhage was 4.2% (95% CI: 2.4–6.0). Postpartum hemorrhage was significantly associated with current antepartum hemorrhage (AOR = 11.67; 95%CI: 7.17–16.17), twin delivery (AOR = 6.59, 95%CI: 1.48–11.70), uterine atony (AOR = 8.45, 95%CI: 4.35–12.55), and prolonged labor (AOR = 5.6, 95%CI: 2.9–8.50).

Conclusions

The prevalence of primary postpartum hemorrhages in the Gedeo Zone, Southern Ethiopia was 4.2%. Current ante partum hemorrhage, twin delivery, uterine atony, and prolonged labor were predictors of primary postpartum hemorrhage. The results back up the necessity for care in the early postpartum period so that clinicians may quickly identify any issues, prevent and start treating excessive blood loss early, and, taking into account the aforementioned factors, possibly reduce the frequency of primary postpartum hemorrhage.