bluuebunny/crossref_metadata_2025 huggingface dataset:
Towards Accurate Boundary Conditions for CFD Models of Synthetic Jets in Quiescent Flow
Authors: Matiz-Chicacausa Andrea , Lopez Mejia Omar D.
Published: December 2020

In this paper, an accurate model to simulate the dynamics of the flow of synthetic jets (SJ) in quiescent flow is proposed. Computational modeling is an effective approach to understand the physics involved in these devices, commonly used in active flow control for several reasons. For example, SJ actuators are small; hence, it is difficult to experimentally measure pressure changes within the cavity. Although computational modeling is an advantageous approach, experiments are still the main technique employed in the study of SJs due to the lack of accurate computational models. The same aspect that represents an advantage over other techniques also represents a challenge for the computational simulations, such as capturing the unsteady phenomena, localized compressible effects, and boundary layer formation characteristic of this complex flow. One of the main challenges in the simulation of SJs is related to the fact that the spatial and temporal scales of the actuator and the corresponding flow control application differed in several orders of magnitude. Hence, in this study we focus on the use of Computational Fluid Dynamics (CFD) and Reduced Order Models (ROM) to develop an accurate yet low-cost model to capture the complexities of the flow of a SJ in quiescent flow. Numerical results show two possible paths for SJ modeling; (1) to obtain a boundary condition to predict velocity profile and jet formation from experimental data of diaphragm’s deformation; and, (2) to predict peak velocity at the jet’s outlet with a ROM approach and to use the physical details of the actuator to develop an accurate boundary condition for CFD. Both approaches are validated through experimental data available in the literature; good agreement between results from CFD, Lumped Element Model (LEM), and experimental data are achieved. Finally, it was concluded that the coupling between LEM and CFD is a novel and accurate approach, which improves CFD due to the advantages of LEM closing the gap between LEM’s lack of flow detail and CFD’s lack of geometrical/physical information of the actuator.
Detailed Analytical Approach to Solve the Magnetoacoustic Tomography with Magnetic Induction (MAT-MI) Problem for Three-Layer Objects
Authors: Zywica Adam Ryszard , Ziolkowski Marcin , Gratkowski Stanislaw
Published: December 2020

This paper is devoted to an analytical approach to the magnetoacoustic tomography with magnetic induction (MAT-MI) problem for three-layer low-conductivity objects. For each layer, we determined closed-form analytical expressions for the eddy current density and Lorentz force vectors based on the separation of variables method. Next, the analytical formulas were validated with numerical solutions obtained with the help of the finite element method (FEM). Based on the acoustic dipole radiation theory, the influence of the transducer reception pattern on MAT-MI was investigated. To obtain acoustic wave patterns, as a system transfer function we proposed the Morlet wavelet. Finally, image reconstruction examples for objects of more complex shapes are presented, and the influence of the MAT-MI scanning resolution and the presence of the noise on the image reconstruction quality was studied in detail.
Role of Electric Vehicles in Transition to Low Carbon Power System—Case Study Croatia
Authors: Tomšić Željko , Raos Sara , Rajšl Ivan , Ilak Perica
Published: December 2020

One of the major tools for the implementation of low carbon strategy goals is increasing the penetration of renewable sources, which are mostly intermittent in nature, into the power system that also increases the needs for additional storage and flexibility capacity in the system. Among other possible solutions, one very most promising tool is the significant electrification of the transport sector. A slightly modified and already verified power system model used for Croatian low-carbon strategy was used here. The PLEXOS software was used to model the Croatian power system by simulating different scenarios. Two scenarios were examined: with and without electric vehicles. This research aimed to evaluate the total decrease in CO2 emissions from both the transport and power sectors due to the increased number of electrical vehicles. The analysis of the Croatian power system was used to assess the flexibility potential of such a large number of electrical vehicles on power system flexibility while considering the volatile nature of wind and solar. Additionally, a question regarding solar availability and simultaneous low-availability of parked electrical vehicles was also examined.
Comparative Study of Tetra-N-Butyl Ammonium Bromide and Cyclopentane on the Methane Hydrate Formation and Dissociation
Authors: Chanakro Warintip , Jaikwang Chutikan , Inkong Katipot , Kulprathipanja Santi , Rangsunvigit Pramoch
Published: December 2020

Two widely investigated methane hydrate promoters, tetra-n-butyl ammonium bromide (TBAB) and cyclopentane (CP), for methane hydrate formation and dissociation were comparatively investigated in the quiescent reactor at 2.5 °C and 8 MPa. The results indicated that the increase in the mass fraction TBAB decreased the induction time. However, it did not significantly affect the methane uptake. In the presence of CP, the increase in the CP concentration resulted in an increase in the induction time due to the increasing thicknesses of the CP layer in the unstirred reactor. Moreover, the methane uptake was varied proportionally with the CP concentration. The addition of TBAB resulted in a higher methane uptake than that of CP, since the presence of TBAB provided the cavities in the hydrate structure to accommodate the methane gas during the hydrate formation better than that of CP. On the contrary, the presence of CP significantly increased the induction time. Although the methane recovery remained relatively the same regardless of TBAB and CP concentrations, the recovery was higher in the presence of TBAB.
Lightning Performance and Economic Analysis of an Overhead 88 kV Power Delivery Network with Enhanced Protective Systems
Authors: Singh Eddie , Davidson Innocent E. , Malanda Sindisiwe C.
Published: December 2020

Earthing and protective devices such as line surge arrestors (LSAs) play an important role in areas with high lightning occurrence for overhead HVAC lines’ performance. A lightning stroke of high magnitude can lead to back flash-overs, and the resultant power surge on the phase conductor can cause instigate the line breaker operating to extinguish the power surge. This operation of the protective devices leads to consumer interruptions on the network, a loss of production, and negatively affects the economy. Studies have shown that reducing an earthing system’s values, which itself is costly, may not be sufficient to prevent back flashover and the associated customer production cost loss. A code was developed to determine the possibility of back flashover and the cost of various earthing schemes utilizing the MATLAB software analysis tool. This paper determines the possibility of a back flashover for various combinations of lightning strokes and earthing profiles. Tower Footing Resistances as low as 9.8 Ω can cause back flashover, provided the lightning stroke exceeds 12 kA. Furthermore, the paper presents and discusses an innovative hybrid power line protection scheme, which estimates and considers the high cost associated with establishing an earthing system; it examines the impracticality of re-engineering an earthing scheme for implementation and results obtained by the inclusion of lightning surge arrester’s (LSA). The cost-saving resulting from dips is also established over 25 years for an 88 kV line, and the breakeven point is established. The results showed that the best scenario would be to reduce the tower footing resistance to 29.1 Ω and install 11 LSA per phase.
Comparative Assessment of Spray Behavior, Combustion and Engine Performance of ABE-Biodiesel/Diesel as Fuel in DI Diesel Engine
Authors: Algayyim Sattar Jabbar Murad , Wandel Andrew P.
Published: December 2020

This study investigates the impact of an acetone-butanol-ethanol (ABE) mixture on spray parameters, engine performance and emission levels of neat cottonseed biodiesel and neat diesel blends. The spray test was carried out using a high-speed camera, and the engine test was conducted on a variable compression diesel engine. Adding an ABE blend can increase the spray penetration of both neat biodiesel and diesel due to the low viscosity and surface tension, thereby enhancing the vaporization rate and combustion efficiency. A maximum in-cylinder pressure value was recorded for the ABE-diesel blend. The brake power (BP) of all ABE blends was slightly reduced due to the low heating values of ABE blends. Exhaust gas temperature (EGT), nitrogen oxides (NOx) and carbon monoxide (CO) emissions were also reduced with the addition of the ABE blend to neat diesel and biodiesel by 14–17%, 11–13% and 25–54%, respectively, compared to neat diesel. Unburnt hydrocarbon (UHC) emissions were reduced with the addition of ABE to diesel by 13%, while UHC emissions were increased with the addition of ABE to biodiesel blend by 25–34% compared to neat diesel. It can be concluded that the ABE mixture is a good additive blend to neat diesel rather than neat biodiesel for improving diesel properties by using green energy for compression ignition (CI) engines with no or minor modifications.
Cost-Economic Analysis of Hydrogen for China’s Fuel Cell Transportation Field
Authors: Luo Zixuan , Hu Yang , Xu Huachi , Gao Danhui , Li Wenying
Published: December 2020

China has become a major market for hydrogen used in fuel cells in the transportation field. It is key to control the cost of hydrogen to open up the Chinese market. The development status and trends of China’s hydrogen fuel industry chain were researched. A hydrogen energy cost model was established in this paper from five aspects: raw material cost, fixed cost of production, hydrogen purification cost, carbon trading cost, and transportation cost. The economic analysis of hydrogen was applied to hydrogen transported in the form of high-pressure hydrogen gas or cryogenic liquid hydrogen and produced by natural gas, coal, and electrolysis of water. It was found that the cost of hydrogen from natural gas and coal is currently lower, while it is greatly affected by the hydrogen purification cost and the carbon trading price. Considering the impact of future production technologies, raw material costs, and rising requirements for sustainable energy development on the hydrogen energy cost, it is recommended to use renewable energy curtailment as a source of electricity and multi-stack system electrolyzers as large-scale electrolysis equipment, in combination with cryogenic liquid hydrogen transportation or on-site hydrogen production. Furthermore, participation in electricity market-oriented transactions, cross-regional transactions, and carbon trading can reduce the cost of hydrogen. These approaches represent the optimal method for obtaining inexpensive hydrogen.
The Prediction of Stiffness Reduction Non-Linear Phase in Bamboo Reinforced Concrete Beam Using the Finite Element Method (FEM) and Artificial Neural Networks (ANNs)
Authors: Muhtar
Published: December 2020

This paper discusses the reduction of the stiffness of bamboo reinforced concrete (BRC) beams to support the use of bamboo as an environmentally friendly building material. Calculation of cross-section stiffness in numerical analysis is very important, especially in the non-linear phase. After the initial crack occurs, the stiffness of the cross-section will decrease with increasing load and crack propagation. The calculation of the stiffness in the cross-section of the concrete beam in the non-linear phase is usually approximated by giving a reduction in stiffness. ACI 318-14 provides an alternative, reducing the stiffness of the plastic post-linear beam section through the moment of inertia (I) of the beam section for elastic analysis between 0.50Ig–0.25Ig. This study aims to predict the value of the reduction in the stiffness of the BRC beam section in the non-linear phase through the load-displacement relationship of experimental results validated by the Finite Element Method (FEM) and the Artificial Neural Networks (ANN) method. The experiment used 8 BRC beams and one steel-reinforced concrete (SRC) beam of singly reinforced with a size of 75 mm × 150 mm × 1100 mm. The beams were tested using a four-point loading method. The analysis results showed that the value of the stiffness reduction in the beam cross-sectional in the non-linear phase ranged from 0.5Ig–0.05Ig for BRC beams, and 0.75Ig–0.40Ig for SRC beams.
Moderate- to High-Severity Disturbances Shaped the Structure of Primary Picea Abies (L.) Karst. Forest in the Southern Carpathians
Authors: Spînu Andreea Petronela , Petrițan Ion Catălin , Mikoláš Martin , Janda Pavel , Vostarek Ondřej , Čada Vojtěch , Svoboda Miroslav
Published: December 2020

Research Highlights: Past disturbances occurred naturally in primary forests in the Southern Carpathians. High- and moderate-severity disturbances shaped the present structure of these ecosystems, which regenerated successfully without forestry interventions. Background and Objectives: Windstorms and bark beetle outbreaks have recently affected large forest areas across the globe, causing concerns that these disturbances lie outside the range of natural variability of forest ecosystems. This often led to salvage logging inside protected areas, one of the main reasons for primary forest loss in Eastern Europe. Although more than two-thirds of temperate primary forests in Europe are located in the Carpathian region of Eastern Europe, knowledge about how natural disturbances shape the forest dynamics in this region is highly essential for future management decisions. Material and Methods: We established our study in a primary forest valley situated in the centre of the largest temperate primary forest landscape in Europe (Făgăraș Mountains). A dendrochronological investigation was carried out to reconstruct the natural disturbance history and relate it to the present forest structure. Results: The dendrochronological analysis revealed high temporal variability in the disturbance patterns both at the patch and stand level. Moderate severity disturbance events were most common (20–40% of canopy disturbed in 60% of the plots) but high severity events did also occur (33% of the plots). Regeneration was spruce-dominated and 71% of the seedlings were found on deadwood microsites. Conclusions: We conclude that the current structure of the studied area is a consequence of the past moderate-severity disturbances and sporadic high-severity events. The peak in disturbances (1880–1910) followed by reduced disturbance rates may contribute to a recent and future increase in disturbances in the Făgăraș Mts. Our findings show that these disturbance types are within the range of natural variability of mountain spruce forests in the Southern Carpathians and should not be a reason for salvage logging in primary forests from this area.
The Effect of Crown Social Class on Bark Thickness and Sapwood Moisture Content in Norway Spruce
Authors: Krajnc Luka , Gričar Jožica
Published: December 2020

The research study examined the effect of tree properties (crown social class, diameter at breast height (DBH), and tree height) on bark thickness (BT) and sapwood moisture content (SMC) in Norway spruce (Picea abies (L.) H. Karst.). Both examined variables were shown to be positively affected by DBH and tree height. The relationship between DBH and SMC varied among crown social classes, while the relationship between DBH and BT was relatively constant across crown social classes. Crown social class had a relatively small effect on BT and SMC, having a more pronounced effect on SMC than on BT. The relationship between tree height and BT did not vary across crown social classes, while the relationship between SMC and tree height was found to change slightly across crown social classes. Measurements of BT and SMC in the field are affordable, fast, and easy to use. Both variables could potentially be used to improve predictions of bark beetle attacks, as they reflect the physiological state of an individual tree.
Effect of Functional Surfaces with Gradient Mixed Wettability on Flow Boiling in a High Aspect Ratio Microchannel
Authors: Ahmadi Vahid Ebrahimpour , Aboubakri Akam , Sadaghiani Abdolali Khalili , Sefiane Khellil , Koşar Ali
Published: December 2020

Flow boiling is one of the most effective phase-change heat transfer mechanisms and is strongly dependent on surface properties. The surface wettability is a crucial parameter, which has a considerable effect on the heat transfer performance, particularly in flow boiling. The contact angle determines the number of nucleation sites as well as bubble dynamics and flow patterns. This study introduces three new generation mixed wettability surfaces and compares them with a wholly hydrophobic surface reference sample, in flow boiling in a high aspect ratio microchannel. The mixed wettability substrates have five regions as fully Al2O3, (hydrophobic zone) region, three different patterned configurations with various A* values, and fully SiO2 (hydrophilic zone) region, where A* is defined as A Al2O3/A total (hydrophobicity ratio). Boiling heat transfer results were obtained for each surface at various wall heat fluxes and three different mass fluxes. According to the obtained results, significant enhancements in heat transfer (by up to 56.7%) could be obtained with biphilic surfaces compared to the reference sample (hydrophobic surface). Performed flow visualization proves that the tested biphilic surfaces enhance heat transfer by reducing the bubbly flow regime and extending the slug regime.
Transgressive Architecture of Coastal Barrier Systems in the Ofanto Incised Valley and Its Surrounding Shelf in Response to Stepped Sea-Level Rise
Authors: De Santis Vincenzo , Caldara Massimo , Pennetta Luigi
Published: December 2020

Coastal deposits/barriers react to sea-level rise through rollover or overstepping. Preserved coastal deposits/barriers allow us to examine coastal responses to sea-level rise, an important aspect within the context of climate change. This study identifies the Ofanto incised valley and examines the possible factors that caused the considerable difference in shape between this valley and adjacent valleys: the Carapelle and Cervaro incised valley and Manfredonia incised valley. In addition, this study assesses the response of transgressive units to stepped sea-level rise with a focus on the evolution of palaeo-barriers/shorelines on the continental shelf and within the infill of Ofanto incised valley. We identified the traces of two slowstands in sea-level rise: the first, short-lived at a centennial scale, interrupted Meltwater Pulse 1A; the second is referable to part of Bølling-Allerød and Younger Dryas. During these two slowstands, two barrier-shoreface/estuarine-backbarrier systems formed. Meltwater Pulse 1A and Meltwater Pulse 1B led to overstepping and partial preservation of these systems in the form of aligned topographic highs. The second slowstand gave rise to continuous landward backstepping of the coastal barrier system; during the following Meltwater Pulse 1B (MWP-1B), landward rollover of the coeval barrier/backbarrier system occurred.
Assessment of Current Gene Therapy Practices in Hepatocellular Carcinoma
Authors: Mckiver Bryan , Damaj Mohamad Imad , Sarkar Devanand
Published: December 2020

Hepatocellular carcinoma (HCC) is the most common form of primary liver cancer and the fifth most common cancer worldwide. HCC is recognized as the fourth most common cause of cancer related deaths worldwide due to the lack of effective early diagnostic tools, which often leads to individuals going undiagnosed until the cancer has reached late stage development. The current FDA approved treatments for late stage HCC provide a minimal increase in patient survival and lack tumor specificity, resulting in toxic systemic side effects. Gene therapy techniques, such as chimeric antigen receptor (CAR)-T Cells, viral vectors, and nanoparticles, are being explored as novel treatment options in various genetic diseases. Pre-clinical studies using gene therapy to treat in vitro and in vivo models of HCC have demonstrated potential efficacy for use in human patients. This review highlights genetic targets, techniques, and current clinical trials in HCC utilizing gene therapy.
A Kindergarten-Based Oral Health Preventive Approach for Hong Kong Preschool Children
Authors: Chai Hollis Haotian , Gao Sherry Shiqian , Chen Kitty Jieyi , Duangthip Duangporn , Lo Edward Chin Man , Chu Chun Hung
Published: December 2020

Early childhood caries (ECC) remains the single most common chronic childhood disease. Untreated caries can cause tooth loss and compromised dentition. Severe ECC can also influence nutrition intake, cognitive development, general health and quality of life. In Hong Kong, approximately half of 5-year-old children suffer from ECC, and more than 90% of these caries remain untreated. Thus, the development of effective strategies for promoting the oral health of preschool children is warranted. The Faculty of Dentistry of the University of Hong Kong has provided kindergarten-based dental outreach services to selected kindergartens since 2008. In 2020, the project expanded to serve all kindergarten children in Hong Kong. The aim of the service is to improve oral health through the prevention and control of ECC among preschool children. The service provides dental screening and silver diamine fluoride treatment for ECC management. In addition, the parents receive oral health talks, and teachers receive training in delivering regular oral health education at kindergarten. The objectives of this service are to improve oral and general health of preschool children, develop the children’s good oral health-related behaviours, maintain the children’s psychological well-being and reduce the burden on their family. This paper describes this kindergarten-based dental outreach service.
Television Viewing and Cognitive Dysfunction of Korean Older Adults
Authors: Jung Mi Sook , Chung Eunyoung
Published: December 2020

This study examined the association between television (TV) viewing and cognitive dysfunction in elderly Koreans. Among participants of the 2014 National Survey of Older Koreans, 9644 were considered in this study. To better identify the association between two factors, propensity score (PS) matching with exact method was used. Finally, 168 viewers and non-viewers each were selected based on estimated PS on key variables and eliminating double matches. Multivariate logistic regression analysis was performed when controlling for possible covariates. Viewers were more likely to have cognitive dysfunction than non-viewers, with significant differences in most covariates. After correcting confounding effects of these covariates with PS matching, TV viewing was found to be a significant risk factor of cognitive dysfunction, along with absence of diagnosed hypertension and non-participation in physical leisure activities. TV viewing might be associated with increased risk of cognitive dysfunction in later life. Appropriate education and strategies to minimize TV viewing among older adults should be established to contribute to attenuating cognitive aging. More interventional studies can help older adults, caregivers, and healthcare professionals explore the cognitively beneficial alternatives to TV use considering the impact of socioeconomic factors of selecting TV viewing as a preferred leisure activity.
The Effect of Spinal Manipulation on the Electrophysiological and Metabolic Properties of the Tibialis Anterior Muscle
Authors: Niazi Imran Khan , Kamavuako Ernest Nlandu , Holt Kelly , Janjua Taha Al Muhammadee , Kumari Nitika , Amjad Imran , Haavik Heidi
Published: December 2020

There is growing evidence showing that spinal manipulation increases muscle strength in healthy individuals as well as in people with some musculoskeletal and neurological disorders. However, the underlying mechanism by which spinal manipulation changes muscle strength is less clear. This study aimed to assess the effects of a single spinal manipulation session on the electrophysiological and metabolic properties of the tibialis anterior (TA) muscle. Maximum voluntary contractions (MVC) of the ankle dorsiflexors, high-density electromyography (HDsEMG), intramuscular EMG, and near-infrared spectroscopy (NIRS) were recorded from the TA muscle in 25 participants with low level recurring spinal dysfunction using a randomized controlled crossover design. The following outcomes: motor unit discharge rate (MUDR), strength (force at MVC), muscle conduction velocity (CV), relative changes in oxy- and deoxyhemoglobin were assessed pre and post a spinal manipulation intervention and passive movement control. Repeated measures ANOVA was used to assess within and between-group differences. Following the spinal manipulation intervention, there was a significant increase in MVC (p = 0.02; avg 18.87 ± 28.35%) and a significant increase in CV in both the isometric steady-state (10% of MVC) contractions (p < 0.01; avg 22.11 ± 11.69%) and during the isometric ramp (10% of MVC) contractions (p < 0.01; avg 4.52 ± 4.58%) compared to the control intervention. There were no other significant findings. The observed TA strength and CV increase, without changes in MUDR, suggests that the strength changes observed following spinal manipulation are, in part, due to increased recruitment of larger, higher threshold motor units. Further research needs to investigate the longer term and potential functional effects of spinal manipulation in various patients who may benefit from improved muscle function and greater motor unit recruitment.
Molecular Characterization and Positive Impact of Brassinosteroids and Chitosan on Solidago canadensis cv. Tara Characteristics
Authors: El-Sayed Iman , Salim Rasha , El-Haggar Eman , El-Ziat Rasha , Soliman Dina
Published: December 2020

Although goldenrod (Solidago canadensis) is considered an invasive plant in many countries, it is a global cut-flower species. In addition, demand for goldenrod has increased significantly in recent years. Thus, the present study aimed to evaluate the response of Solidago canadensis cv. Tara to brassinosteroids (BRs) at levels of 0.10−3, 10−6, and 10−8 M, and chitosan at 0, 100, 150, and 200 mg/L as a foliar application to increase the quality and quantity of production, and its polyphenolic compounds. Moreover, antibacterial activity and genetic polymorphism for both untreated and the optimally treated goldenrod were investigated. The results showed that the highest mean of growth characteristics was found when plants were treated with BRs at 10−8 M, whereas the longer vase life was obtained using 200 mg/L chitosan. Furthermore, higher pigment values, N, P, K, and total phenolic content, antioxidant capacity, chlorogenic acid, and rutin content were detected on plants treated with 200 mg/L chitosan. In addition, foliar application with 200 mg/L chitosan caused higher antibacterial activity among the control and BRs. The optimal treatment of BR at 10−8 M (89%) showed a low genetic similarity, based on sequence-related amplified polymorphism (SRAP) analysis, comparable with the control and 200 mg/L chitosan. BR at 10−8 M and 200 mg/L chitosan showed a significant enhancement of growth parameters. As a result, it can be concluded that goldenrod, as a herb extract, shows significant promise as a natural preservative in pharmaceutical, food, and cosmetic products.
Post-Traumatic Stress Disorder and Associated Factors during the Early Stage of the COVID-19 Pandemic in Norway
Authors: Bonsaksen Tore , Heir Trond , Schou-Bredal Inger , Ekeberg Øivind , Skogstad Laila , Grimholt Tine K.
Published: December 2020

The COVID-19 outbreak and the sudden lockdown of society in March 2020 had a large impact on people’s daily life and gave rise to concerns for the mental health in the general population. The aim of the study was to examine post-traumatic stress reactions related to the COVID-19 pandemic, the prevalence of symptom-defined post-traumatic stress disorder (PTSD), and factors associated with post-traumatic stress in the Norwegian population during the early stages of the COVID-19 outbreak. A survey was administered via social media channels, to which a sample of 4527 adults (≥18 years) responded. Symptom-defined PTSD was measured with the PTSD Checklist for the DSM-5. The items were specifically linked to the COVID-19 pandemic. We used the DSM-5 diagnostic guidelines to categorize participants as fulfilling the PTSD symptom criteria or not. Associations with PTSD were examined with single and multiple logistic regression analyses. The prevalence of symptom-defined PTSD was 12.5% for men and 19.5% for women. PTSD was associated with lower age, female gender, lack of social support, and a range of pandemic-related variables such as economic concerns, expecting economic loss, having been in quarantine or isolation, being at high risk for complications from COVID-19 infection, and having concern for family and close friends. In conclusion, post-traumatic stress reactions appear to be common in the Norwegian population in the early stages of the COVID-19 outbreak. Concerns about finances, health, and family and friends seem to matter.
Smart and Age-Friendly Cities in Russia: An Exploratory Study of Attitudes, Perceptions, Quality of Life and Health Information Needs
Authors: Ziganshina Liliya Eugenevna , Yudina Ekaterina V. , Talipova Liliya I. , Sharafutdinova Guzel N. , Khairullin Rustem N.
Published: December 2020

In Russia, initiatives for healthy ageing have been growing over the last two decades; however, none use an evidence-based (EB) approach. It is proposed that Kazan, a city with a population of over a million in the European part of Russia, has good chances of moving towards age-friendliness and contributing to raising awareness about healthy ageing through Cochrane evidence. One of the eight essential features of age-friendly cities by the World Health Organisation (WHO) directly points to health services. This exploratory study assesses the health information needs of the ageing population of Kazan and the challenges people face in improving their health and longevity. Survey data were used from 134 participants, patients, caregivers and healthcare providers of the Interregional Clinical Diagnostic Centre (ICDC), aged from 30 to over 80 years, and potential associations of the studied parameters with age, gender, quality of life and other characteristics were analysed. Older people (60+) were less positive about their quality of life, took medicines more often on a daily basis (10/16 compared to 29/117 of people under 60), encountered problems with ageing (9/16 compared to 21/117 of people under 60) and rated their quality of life as unsatisfactory (4/14 compared to 9/107 of people under 60). Awareness of EB approaches and Cochrane was higher within health professions (evidence-based medicine: 42/86 vs. 13/48; Cochrane: 32/86 vs. 2/48), and health information needs did not differ between age or gender groups or people with a satisfactory and unsatisfactory quality of life. The minority (10%—13/134) were aware of ageism without age or gender differences. The low awareness calls for the need of Cochrane intervention both for consumers and those in the health profession to raise awareness to contribute to Kazan moving towards an age-friendly city.
The Incidence of Intestinal Gastric Cancer among Resettlers in Germany—Do Resettlers Remain at an Elevated Risk in Comparison to the General Population?
Authors: Lindblad Anna , Kaucher Simone , Jaehn Philipp , Kajüter Hiltraud , Holleczek Bernd , Lissner Lauren , Becher Heiko , Winkler Volker
Published: December 2020

Objective: Previous studies have shown that the incidence of gastric cancer (GC), and particularly intestinal GC, is higher among resettlers from the former Soviet Union (FSU) than in the general German population. Our aim was to investigate if the higher risk remains over time. Methods: GC cases between 1994 and 2013, in a cohort of 32,972 resettlers, were identified by the respective federal cancer registry. Age-standardized rates (ASRs) and standardized incidence ratios (SIRs) were analyzed in comparison to the general population for GC subtypes according to the Laurén classification. Additionally, the cohort was pooled with data from a second resettler cohort from Saarland to investigate time trends using negative binomial regression. Results: The incidence of intestinal GC was elevated among resettlers in comparison to the general population (SIR (men) 1.64, 95% CI: 1.09–2.37; SIR (women) 1.91, 95% CI: 1.15–2.98). The analysis with the pooled data confirmed an elevated SIR, which was stable over time. Conclusion: Resettlers’ higher risk of developing intestinal GC does not attenuate towards the incidence in the general German population. Dietary and lifestyle patterns might amplify the risk of GC, and we believe that further investigation of risk behaviors is needed to better understand the development of disease pattern among migrants.
The Association between Plasma ERVWE1 Concentrations and Affective Symptoms during Pregnancy: Is This a Friendly Alien?
Authors: Serati Marta , Esposito Cecilia Maria , Grassi Silvia , Bollati Valentina , Barkin Jennifer Lynn , Buoli Massimiliano
Published: December 2020

Human endogenous retroviruses (HERVs) comprise 8% of the human genome, and HERV DNA was reported to be essential in human embryonic development. Specifically, HERV-W encodes a protein, syncytin-1, alternatively known as ERVWE1 (Human Endogenous Retrovirus W EnvC7-1 Envelope Protein), participating in human placental morphogenesis and having a role in immune system regulation. Syncytin-1 activity is increased in neuropsychiatric disorders, autoimmune diseases, and cancer. In our study, forty-four women in the third trimester of pregnancy were tested for ERVWE1 plasma levels. In concomitance with blood samples the following rating scales were administered to women: the Edinburgh Postnatal Depression Scale (EPDS), State Anxiety Inventory (STAI-S), Trait Anxiety Inventory (STAI-T), and Prenatal Attachment Inventory (PAI). We found that higher ERVWE1 protein plasma levels were significantly associated with higher PAI scores (p = 0.02), an earlier gestational age at the time of blood collection (p = 0.01), a longer duration of symptoms (p = 0.03), and fewer lifetime attempted suicides (p = 0.02). Our results seem to support the role of ERVWE1 in maintaining clinical psychiatric symptoms as a result of potential prolonged inflammation. At the same time, this protein may have a protective role in pregnant women by a reduction of suicidal behavior and a better mother–fetus relationship.
Cell Viability and Immune Response to Low Concentrations of Nickel and Cadmium: An In Vitro Model
Authors: Kim Ahra , Park SangJin , Sung Joo Hyun
Published: December 2020

Environmental exposure to low concentrations of heavy metals is common in the general population, but the toxicity, immune response mechanisms, and the effects of single and mixed metal exposures have not been clearly identified. In this study, A549 cells and Raw264.7 cells were exposed to low concentrations of the heavy metals nickel (Ni) and cadmium (Cd) for 24, 48, and 72 h, and then cell viability and cytokine levels were analyzed. We found that exposure to low concentrations of Ni (50 nM) or Cd (10 nM) alone did not affect cell viability. However, mixing them together decreased cell viability. In addition, the levels of IL-10, IL-12, and TNF-α decreased with single (only Cd) and mixed (Ni and Cd) exposures. These results show that exposure to low concentrations of heavy metals could affect the normal immune response, even without obvious clinical manifestations. Therefore, chronic exposure to heavy metals might have adverse effects on overall health.
Urinary Mercury Levels and Predictors of Exposure among a Group of Italian Children
Authors: Astolfi Maria Luisa , Vitali Matteo , Marconi Elisabetta , Martellucci Stefano , Mattei Vincenzo , Canepari Silvia , Protano Carmela
Published: December 2020

Urinary mercury (Hg) levels are suitable to assess long-term exposure to both elemental and inorganic Hg. In this study, the urinary Hg levels of 250 children (aged 6–11 years) from three areas with different anthropogenic impacts in the Rieti province, central Italy, were assessed. The Hg concentrations were in the range of 0.04–2.18 µg L−1 with a geometric mean equal to 0.18 µg L−1 [95% confidence interval (CI), 0.17–0.20 µg L−1] or 0.21 µg g−1 creatinine (95% CI, 0.19–0.23 µg g−1 creatinine), and a reference value calculated as 95th percentile of 0.53 µg L−1 (95% CI, 0.44–0.73 µg L−1) or 0.55 µg g−1 creatinine (95% CI, 0.50–0.83 µg g−1 creatinine). In all cases, urinary Hg data were below the HBM-I values (7 µg L−1 or 5 µg g−1 creatinine) established for urine, while the 95th percentile was above the German Human Biomonitoring Commission’s RV95 (0.4 µg L−1) set for children without amalgam fillings. A significant correlation (p < 0.05) was found between creatinine-corrected results and residence area, with higher urinary Hg levels in children living in the industrial area. Multiple linear regression analysis showed that creatinine was the main predictor of urinary Hg.
The Influence of Different Auditory Stimuli on Attentiveness and Responsiveness in Road Traffic in Simulated Traffic Situations
Authors: Welz Wolfgang , Voelter-Mahlknecht Susanne , Große-Siestrup Christian , Preuß Geraldine
Published: December 2020

The use of portable media has become an integral part of our increasingly mobile society. The use of digital audio books is also growing steadily in Germany. The connection between the psychological effect of music of different volumes and rhythms and the change in reaction in road traffic with a corresponding increase in risk behavior, especially when driving, has already been proven in previous studies. Only a few studies are available on the effects of listening to radio plays on reaction behavior and concentration in road traffic as well as on risk behavior among pedestrians and cyclists. In the present study, we have investigated the influences of pop music and a radio play on reaction behavior and thus driving ability during the execution of a traffic psychological test series from the “Wiener Test System”. The central topic deals with the performance of the test subjects in the individual tests. Conclusions are drawn on the reaction behavior and concentration during participation in road traffic and thus the risk of distraction and possible increased risk of accidents. Studies on the influence of auditory stimuli and their effects on concentration and reaction during participation in traffic are of great interest from the point of view of traffic psychology and occupational medicine, since a reduction in the risk of accidents can increase general traffic safety and lead to a decrease in sick leave and therefore fewer absences from work.
Is Adiposity Associated with the Quality of Movement Patterns in the Mid-Adolescent Period?
Authors: Karuc Josip , Marković Goran , Mišigoj-Duraković Marjeta , Duncan Michael J. , Sorić Maroje
Published: December 2020

This study examined the association between functional movement (FM) and adiposity in adolescent population (16–17 years). This study was conducted in a representative sample of urban adolescents as the part of the CRO-PALS longitudinal study (n = 652). Body mass index (BMI), a sum of four skinfolds (S4S), waist and hip circumference were measured, and FM was assessed via Functional Movement ScreenTM (FMSTM). Furthermore, total FMSTM screen was indicator of FM with the composite score ranged from 7 to 21, with higher score indicating better FM. Multilevel analysis was employed to determine the relationship between different predictors and total FMS score. In boys, after controlling for age, moderate-to-vigorous physical activity, and socioeconomic status, total FMS score was inversely associated only with BMI (β = −0.18, p < 0.0001), S4S (β = −0.04, p < 0.0001), waist circumference (β = −0.08, p < 0.0001), and hip circumference (β = −0.09, p < 0.0001). However, among girls, in adjusted models, total FMS score was inversely associated with S4S (β = −0.03, p < 0.0001), while BMI (β = −0.05, p = 0.23), waist circumference (β = −0.04, p = 0.06), and hip circumference: (β = −0.01, p = 0.70) failed to reach statistical significance. Results showed that the association between adiposity and FM in adolescence is sex-specific, suggesting that boys with overweight and obesity could be more prone to develop dysfunctional movement patterns. Therefore, exercise interventions directed toward correcting dysfunctional movement patterns should be sex-specific, targeting more boys with overweight and obesity rather than adolescent girls with excess weight.
Association between Exposure to Ambient Air Pollution and Age-Related Cataract: A Nationwide Population-Based Retrospective Cohort Study
Authors: Shin Jinyoung , Lee Hyungwoo , Kim Hyeongsu
Published: December 2020

This study aimed to investigate the association between ambient air pollutants and cataracts in the general population aged 50 years or older using data from the Korean National Insurance Service—National Sample Cohort. Cataract patients were defined as those diagnosed by a physician and having undergone cataract surgery. After matching the average concentrations of PM2.5, PM10, NO2, CO, SO2, and O3 in residential areas, the association between quartile level of air pollutants and incidence of cataract was analyzed using a multivariate Cox-proportional hazard risk model. Among the 115,728 participants, 16,814 (14.5%) were newly diagnosed with cataract and underwent related surgery between 1 January 2004, and 31 December 2015. Exposure to PM10, NO2, and SO2 was positively associated with cataract incidence, while O3 was negatively associated. The adjusted hazard ratio (HR) with 95% confidence interval was 1.069 (1.025–1.115) in PM10 and 1.080 (1.030–1.133) in NO2. However, the association between cataract and the quartile of PM2.5 measured during one year in 2015 was not clear. The HR of female participants aged 65 or older was significantly increased according to quartile of air pollutants. We identified exposure to PM10, NO2, SO2, and O3 associated with cataract development in Korean adults aged ≥ 50 years. This information may be helpful for policymaking to control air pollution as a risk factor for eye health.
Effect of Lambdacyhalothrin on Locomotor Activity, Memory, Selected Biochemical Parameters, Tumor Necrosis Factor α, and Interleukin 1ß in a Mouse Model
Authors: Nieradko-Iwanicka Barbara , Konopelko Michał
Published: December 2020

Background: Pyrethroids are synthetic insecticides used for plant protection. They are synthetic analogues of pyrethrins. Lambdacyhalothrin (LCH) is a type II pyrethroid used for wheat, potato, corn farming, and malaria control. There are data that pyrethroids may cause neurotoxicity, nephrotoxicity, hepatotoxicity, and immunotoxicity in non-target organisms. Methods: The experiment was carried on 32 Albino Swiss mice (16 females and 16 males). The animals were divided into four groups. Controls received canola oil; the rest received LCH orally in oil at a dose of 2 mg/kg bw for 7 days. Memory retention was assessed in a passive avoidance task on day 2 and 7, and spatial memory and motor activity in a Y-maze on day 1 and 7. Blood morphology, biochemical tests, tumor necrosis factor α, and interleukin 1ß were measured. Results: Decreased white blood cell count and red blood cell count, increased creatinine, and increased kidney and liver mass were observed in groups exposed to LCH. In LCH-exposed males’ kidneys and livers, interleukin 1ß was significantly elevated, and it was correlated with creatinine concentration. Conclusions: Subacute poisoning with a low dose of LCH does not significantly affect memory nor locomotor activity but increases proinflammatory interleukin 1ß in male livers and kidneys and reduces white and red blood cell counts.
How is Respect and Social Inclusion Conceptualised by Older Adults in an Aspiring Age-Friendly City? A Photovoice Study in the North-West of England
Authors: Ronzi Sara , Orton Lois , Buckner Stefanie , Bruce Nigel , Pope Daniel
Published: December 2020

The World Health Organisation (WHO) Global Age-Friendly Cities (AFC) Guide classifies key characteristics of an AFC according to eight domains. Whilst much age-friendly practice and research have focused on domains of the physical environment, those related to the social environment have received less attention. Using a Photovoice methodology within a Community-Based Participatory Research approach, our study draws on photographs, interviews and focus groups among 26 older Liverpool residents (60+ years) to explore how the city promotes respect and social inclusion (a core WHO AFC domain). Being involved in this photovoice study allowed older adults across four contrasting neighbourhoods to communicate their perspectives directly to Liverpool’s policymakers, service providers and third sector organisations. This paper provides novel insights into how: (i) respect and social inclusion are shaped by aspects of both physical and social environment, and (ii) the accessibility, affordability and sociability of physical spaces and wider social processes (e.g., neighbourhood fragmentation) contributed to or hindered participants’ health, wellbeing, intergenerational relationships and feelings of inclusion and connection. Our findings suggest that respect and social inclusion are relevant across all eight domains of the WHO AFC Guide. It is core to an AFC and should be reflected in both city-based policies and evaluations.
International Prevalence and Correlates of Psychological Stress during the Global COVID-19 Pandemic
Authors: Adamson Maheen M. , Phillips Angela , Seenivasan Srija , Martinez Julian , Grewal Harlene , Kang Xiaojian , Coetzee John , Luttenbacher Ines , Jester Ashley , Harris Odette A. , Spiegel David
Published: December 2020

This study reports perceived stress and associated sociodemographic factors from an international sample of adults, during the COVID-19 pandemic. The Perceived Stress Scale (PSS-10) along with socio-demographic questions were conducted between 8 April 2020 and 11 May 2020. The survey was translated from English into five languages. Recruitment was conducted worldwide using social media. A total of 1685 survey responses were collected across 57 countries with eleven countries (≥30 responses/country) included in the sub-analyses. Overall, the mean PSS-10 score was 19.08 (SD = 7.17), reflecting moderate stress compared to previously reported norms. Female gender was associated with a higher PSS score (3.03, p < 0.05) as well as four-year degree holders (3.29, p < 0.05), while adults over 75 years (−7.46, p < 0.05) had lower PSS scores. Personal care composite score (including hours of sleep, exercise, and meditation) was associated with lower PSS scores (−0.39, p < 0.01). Increases in personal care and changes in work expectations were associated with lower PSS scores (−1.30 (p < 0.05) and −0.38 (p < 0.01), respectively). Lower total PSS scores were reported in Germany (−4.82, p < 0.01) compared to the global response sample mean. This information, collected during the initial period of global mitigation orders, provides insight into potential mental health risks and protective factors during crises.