bluuebunny/crossref_metadata_2025 huggingface dataset:
Imaging the Architecture of Granulomas Induced by Mycobacterium tuberculosis Infection with Single-molecule Fluorescence In Situ Hybridization
Authors: Kumar Ranjeet , Kolloli Afsal , Subbian Selvakumar , Kaushal Deepak , Shi Lanbo , Tyagi Sanjay
Published: June 2024

Granulomas are an important hallmark of Mycobacterium tuberculosis infection. They are organized and dynamic structures created when immune cells assemble around the sites of infection in the lungs that locally restrict M. tuberculosis growth and the host’s inflammatory responses. The cellular architecture of granulomas is traditionally studied by immunofluorescence labeling of surface markers on the host cells. However, very few Abs are available for model animals used in tuberculosis research, such as nonhuman primates and rabbits, and secreted immunological markers such as cytokines cannot be imaged in situ using Abs. Furthermore, traditional phenotypic surface markers do not provide sufficient resolution for the detection of the many subtypes and differentiation states of immune cells. Using single-molecule fluorescence in situ hybridization (smFISH) and its derivatives, amplified smFISH and iterative smFISH, we developed a platform for imaging mRNAs encoding immune markers in rabbit and macaque tuberculosis granulomas. Multiplexed imaging for several mRNA and protein markers was followed by quantitative measurement of the expression of these markers in single cells. An analysis of the combinatorial expressions of these markers allowed us to classify the cells into several subtypes, and to chart their densities within granulomas. For one mRNA target, hypoxia-inducible factor-1α, we imaged its mRNA and protein in the same cells, demonstrating the specificity of the probes. This method paves the way for defining granular differentiation states and cell subtypes from transcriptomic data, identifying key mRNA markers for these cell subtypes, and then locating the cells in the spatial context of granulomas.
Multisystem inflammatory syndrome in children with COVID-19 in a multitransfused patient
Authors: Das Swarnalata , Ranjan Manas Behera , Das Palash
Published: June 2024

Multi-system inflammatory syndrome in children associated with COVID19 (MIS-C) is a unique clinical syndrome characterised by fever, gastrointestinal symptoms, skin and oral rash and or neurological symptoms in the presence of raised acute phase reactants and coagulopathy. Ferritin is an acute phase reactant which is used as a marker of inflammation. Diagnosis of MIS-C in the background of transfusion dependent thalassemia with iron overload needs a strong clinical suspicion. Early diagnosis and prompt treatment are necessary to ensure a rapid uneventful recovery. A three-year-old male child born to non-consanguineously related parents reported to pediatric emergency with difficulty breathing and pain abdomen for one day. The child was a diagnosed case of Beta thalassemia major since the age of one year and was on regular transfusions and was on iron chelation for past eleven months with deferrasirox. Initial clinical examination showed a sick and irritable child with tachypnea tachycardia and hypoxia. Initial investigations showed raised acute phase reactants along with severe anemia. The child was investigated for MIS-C because of unexpected rise of serum ferritin from 1980 ng/mL (October 2020) to 6686 ng/mL (in January 2021) despite being on regular chelation. Antibody titre for SARS COVID-19 was positive. The patient was treated with intravenous corticosteroids and improved with the same. The advent of COVID19 pandemic saw most children having a mild disease with no or minimal symptoms. Some kids however presented with more serious delayed symptoms of MIS-C. To diagnose same in multi transfused patients a strong clinical suspicion and just judgement based on the clinical and laboratory findings should be done. Unexplained rise in ferritin levels, typical symptoms and high probability of exposure to COVID19 helped in clinching diagnosis.
Estimation of serum calcium levels in apheresis platelet donors
Authors: Arpitha P. , Thokala Ravindra Prasad
Published: June 2024

INTRODUCTION:

Apheresis is practiced widely to collect single donor platelets (SDPs). This procedure utilizes an anticoagulant acid citrate dextrose to prevent clotting of blood in the extracorporeal circuit which chelates divalent ions like calcium. This alters the calcium homeostasis resulting in hypocalcemia causing acute adverse events.

AIM:

The study aimed to know the calcium homeostasis in apheresis platelet donors.

MATERIALS AND METHODS:

This cross-sectional study was conducted from January 2020 to December 2020 in the department of transfusion medicine. The sample size was 50. Donors who walk in for voluntary SDP donation were selected. Total and ionized calcium, pH, and serum albumin for all the donors at baseline and ionic calcium at the end of the procedure and 30 min after the procedure were measured.

RESULTS:

According to statistical analysis of the ionic calcium level at pre procedure, immediate post procedure and 30 minutes post procedure, there was decrease in the value immediate post procedure and values returned to baseline within 30 minutes. The levels of pH change were analyzed. On comparing the preprocedure and immediate postprocedure values, there was a significant lowering of pH value from the baseline (P = 0.5), indicating acute lowering of pH immediate postprocedure. Hence, most of the citrate metabolism can be achieved within 30 min after completion of the apheresis procedure.

CONCLUSION:

SDP collection is essentially a safe procedure with minimal adverse effects. Toxicity of citrate is not much pronounced. Recovery of calcium levels is within 30 min of completion of plateletpheresis.
Donor lymphocyte infusions: An experience from a tertiary care center of North India
Authors: Lamba Divjot Singh , Tripathi Parmatma Prasad , Hans Rekha , Khadwal Alka , Sharma Ratti Ram
Published: June 2024

Donor lymphocyte infusions (DLIs) are often recommended products after allogeneic hematopoietic stem cell transplant to increase graft – versus – leukemia effect. More success rate of DLI has been reported in relapsed posttransplant chronic myeloid leukemia. Whatever the indication for DLI, mortality related to post-DLI infusion is 5%–20%, and more than one-third of patients will develop acute and/or chronic graft versus host disease (GVHD) after DLI. We report two cases where DLIs were used for residual disease after posttransplant. Both of DLI went uneventful. None of the patient’s developed signs of GVHD postinfusion. Although both patients expired with different causes, none were related to DLI infusion. Information from published literature suggests that DLI should be administered early after relapse or as a prophylactic strategy in patients receiving T-cell-depleted grafts, and patients with aggressive diseases may benefit from disease reduction before DLI. However, further evidence is required to evaluate its efficacy, especially in relapsed or residual hematological malignancies.
A method for selecting P antigen-negative red cell units for patients with paroxysmal cold hemoglobinuria
Authors: Manchanayake Geethika Sajeewani
Published: June 2024

In the absence of specific antisera and molecular typing technique, selection of P antigen-negative red cell unit is a challenge. This article explains a new technique that can be used in emergency situations to screen P antigen-negative red cell unit for the transfusion of patients with paroxysmal cold hemoglobinuria tested positive for Donath-Landsteiner antibody. The technique is based on the theory behind the Donath-Landsteiner test, and it can be performed even in a transfusion laboratory with minimum facilities.
Psychosocial Burden in Parents Having Intellectually Disabled Children: A Hospital-based Study
Authors: Kumari Reena , Ray Tapas Kumar , Laskar Ananya Ray , Majumdar Ritu
Published: June 2024

Background:

Intellectual disability is a non-communicable health disorder that has become a public health concern worldwide, with a marked impairment in communication, academic, and social skills. It is important to identify the level of psychological stress among parents of these children. Hence, this study was designed to assess the level of psychological stress among parents having intellectually disabled children.

Materials and Methods:

The study was conducted in the Physical Medicine and Rehabilitation outpatient department (OPD) at Kalawati Saran Children’s Hospital, New Delhi. Data were collected to analyze the psychological stress in families. Parental Stress Scale (PSS) was used as the tool to measure stress in parents.

Results:

A total of 170 mothers were enrolled in the study. In total, 14 different variables were considered plausible contributing factors to the mother’s stress. Four variables demonstrated a clear linear association between variable values and PSS. These variables were a) per-capita monthly family income, b) socioeconomic status, c) study subjects’ occupation, and d) duration of disability. The overall mean PSS for the entire cohort was found to be 47.14 ± 2.93. The reference criteria for low stress was 19–45, and it was 45–90 for high stress.

Conclusion:

The study suggests that mothers of children with intellectual disability experience high stress. Raising a child with special care needs is overwhelming for mothers. Appropriate clinical services should be provided to support parents of children with disabilities and offer resources to educate and enable mothers to manage their children’s disabilities and needs.
A Clinico - Microbial Study to Assess the Benefits of Medicinal Plant Extracts in Chronic Periodontitis
Authors: Srivastav Ankita , Ashish Saini , Dharmendra Saikia , Vandana Pant Aditya , Brijesh Sharma
Published: June 2024

Background:

There has been an increasing trend for the development of natural formulations for plaque control using medicinal plants as an adjunct, which can be a feasible alternative as these are widely available, cost-effective, and have fewer side effects.

Aim:

The evaluation of the effects of medicinal plant extracts in chronic periodontitis (CP).

Materials and Methods:

This study was carried out in two phases; first the antibacterial activity of two medicinal plant extracts was tested on periodontal pathogens, thereafter, a clinical assessment was carried out on subjects with CP. Forty-five individuals suffering from CP were randomized into three different groups; Group A: Scaling and root planing (SRP) along with Piper longum rinse, Group B: SRP along with mixture of Tinospora cordifolia and P. longum rinse, Group C: SRP along with chlorhexidine (CHX) (control group). The clinical parameters (gingival index [GI], plaque index, gingival bleeding index [BI], probing pocket depth [PPD], and clinical attachment level [CAL]) were recorded at baseline and months 1 and 3. The intra- and intergroup comparison of clinical parameters for all groups at different time intervals was performed.

Results:

At the end of the trial, all the three groups showed a statistically significant reduction when compared to baseline for all the clinical parameters. In intergroup comparison, statistically significant reduction in GI, PPD, and CAL for both Group A and Group C was seen at 3 months as compared to Group B. Comparable reduction was seen between Group A and C for all the clinical parameters. Reduction in plaque and gingival BI was seen to be highest in Group A.

Conclusion:

P. longum can be effectively utilized as an additive to mechanical periodontal treatment in comparison to CHX mouthwash for CP patients.
Current Status of root Biomodification Agents in Periodontal Regeneration
Authors: Bhatt Niket , Dodwad Vidya , Yewale Manasi , Kulkarni Pranav , Pharne Pooja
Published: June 2024

Periodontitis can be defined as a multifactorial inflammatory disease of bacterial origin causing destruction of periodontal tissues. Achieving effective regeneration in periodontal therapy still remains a foremost goal. Chemical modification of tooth surface has been the most persistent effort to achieve periodontal regeneration. There are controversies regarding effectiveness of root biomodification due to a mixture of results from clinical and histological studies. This review provides an acumen about root biomodification in clinical conditions as well as a summary on the novel biomodification agents.
The Surgical Management of a Cystic Lesion in the Same Cystic Follicle Related to Lateral Incisor and Impacted Permanent Maxillary Canine: (A Case Study)
Authors: Kumari Shilpa , Kanwar Balkaran Singh , Kumar Vijay , Rai Kulwant
Published: June 2024

The most common kind of developing odontogenic cysts are dentigerous cysts. They frequently push impacted teeth into ectopic locations by encircling the crown of the tooth. The mandibular third molar, maxillary canine, mandibular premolar, and maxillary third molar are the teeth that are most commonly afflicted, in decreasing order. Although these cysts are more prevalent in men, they can also occur in children and teenagers, especially in the second and third decades of life. Dentigerous cyst-related teeth in the maxilla frequently cause root dilatation in the mandibular area, permanent tooth bud displacement close to the sinus, and cortical bone enlargement, sometimes, even up to the level of the orbit or floor of the nose. Clinically, these cysts do not cause any symptoms and are frequently found by chance during radiographs done to look into cases of primary teeth that are retained, teeth that are missing, teeth that erupt slowly, or orthodontic issues. Cone-beam computed tomography’s advent has just made it possible to shed fresh, extensively documented light on diagnostic and treatment approaches. Protocol for management: Surgery is typically used to treat dentigerous cysts. In this instance, the affected tooth underwent endodontic therapy, after which the cyst was curettaged, a further apicoectomy was performed, and canine impaction was completed. In the end, a bone graft and platelet-rich fibrin were implanted for rehabilitation.
The effects of an adapted walking program on fatigue levels in individuals with type 2 diabetes: A pilot study
Authors: Singh Rupali , Singh Gurpreet
Published: June 2024

PURPOSE:

Fatigue is a common complaint in people with type 2 diabetes, but there is limited research investigating methods to decrease fatigue. The purpose of this study was to evaluate the effects of a 10-week walking program on fatigue levels in people with type 2 diabetes.

PARTICIPANTS AND METHODS:

The study consisted of 12 individuals (7 males/5 females; average age 59.2 ± 10.6 years and body mass index [BMI] 36.93 ± 7.15 kg/m2). Each participant was given an individualized walking program with a step goal for each week determined by individual fatigue levels. Fatigue was assessed using the Multidimensional Fatigue Inventory (MFI-20). Other outcome measures included; BMI, Pittsburgh Sleep Quality Index, Fasting Blood Glucose, Visual Analog Scale, Diabetes-39, Duke Health Profile, and 6 min Walk Test.

RESULTS:

The Wilcoxon Signed–Ranked Test and Spearman’s Rank Correlation Test were used to determine the effectiveness of the walking intervention and to test the relationship between the number of steps walked and other outcome measures. A decline in fatigue scores (P = .005) was seen after the intervention. An average increase in steps walked negatively correlated with total MFI-20 scores postintervention (r = −0.833; P = .010).

CONCLUSION:

The walking intervention was found to help decrease fatigue in people with type 2 diabetes.
Prevalence of flexible and rigid flatfoot among adolescents and its association with body mass index
Authors: Kaur Mohineet , Kaur Navjot
Published: June 2024

CONTEXT:

Flatfoot is a common foot condition that can be classified into flexible or rigid flatfoot. It is more prevailing among young children, adolescents, and adults. There has been an association seen between flatfoot and increased weight; however, the research is more focused on the prevalence of flatfoot in younger children.

AIMS:

The purpose of the present study is to report the prevalence of the flexible and rigid flatfoot and its association with body mass index (BMI) among adolescents.

SETTINGS AND DESIGN:

One-hundred adolescents including both males and females were included from Sri Guru Harkrishan Public School, Amritsar. Parental consent was obtained through the process of informed consent. The height and weight of subjects were measured using a standard apparatus.

SUBJECTS AND METHODS:

Obesity was calculated by BMI. Flatfoot assessment was done using the Staheli index and plantar arch index (PAI), and flatfoot severity was graded with the Denis method. A relationship between BMI and flatfoot was observed.

STATISTICAL ANALYSIS USED:

Statistical analysis was done using the SPSS 15 version statistical program for Microsoft Windows. The statistical analysis employed included calculating the average, standard deviation, cumulative percentage, conducting a t-test, and performing Pearson’s correlation test. The probability value P ≤ 0.05 was statistically significant.

RESULTS:

Fourteen percent of participants had left flatfoot, and 8% had right flatfoot. Further, left and right flatfoot types were also analyzed, and it was found that 12% of participants had flexible flatfoot on the left, and 5% had it on the right. The results showed a positive correlation between BMI and the right foot (r = 0.222, P = 0.026), indicating that as BMI increases; the right PAI also increases. However, there was no significant correlation between BMI and left foot (r = 0.111, P = 0.273).

CONCLUSIONS:

This study found a low prevalence of flexible and rigid flatfoot among adolescents; however, a positive correlation between BMI and flatfoot was found, indicating that individuals with higher BMI may be at increased risk for flatfoot. The findings of this study suggest that flexible flatfoot is common among adolescents, whereas rigid flatfoot is rare.
Work-related musculoskeletal disorders among traditional pottery makers at selected places in Bengaluru – A cross-sectional study
Authors: Holla Pavana , Shenai Anusha V.
Published: June 2024

CONTEXT:

Pottery is defined as clay that has been fashioned into the desired shape and then dried to reduce its water content before being fried or baked to fix its form. The artisans living in traditional societies are normally influenced by their environment as well as by their myths, legends, rituals, ceremonies, festivals, social organization, and cultural norms which are reflected in their creations. The poor environmental conditions and the lack of protective equipment in these pottery workshops are key contributing factors to the development of these occupational diseases. Most pottery industries are small- to medium-scale industries and have longer and irregular working hours, a higher percentage of elderly employees, limited opportunities for health education or health inspection, and insufficient health promotion facilities compared with large companies. These factors are considered to play an important part in the development of occupational diseases and some nonspecific diseases such as psychosomatic, cardiovascular, and locomotor diseases among pottery workers. Traditional pottery making has its unique method of potter-work where it demands prolonged squatting without back support for hours which can develop musculoskeletal disorders (MSDs).

AIMS:

The study aimed to estimate the prevalence of work-related musculoskeletal disorders (WRMD) among traditional pottery makers at selected places in Bengaluru.

SETTINGS AND DESIGN:

A cross-sectional study was conducted in two rural communities of Bengaluru. One hundred and ten traditional pottery makers were randomly selected.

MATERIALS AND METHODS:

Subjects were screened for work-related musculoskeletal disorders (WRMD) using the Nordic Musculoskeletal Questionnaire, following which the pottery makers who reported low back pain (LBP) were screened for the severity of disability using the Modified Oswestry LBP Disability Questionnaire (M-OSW). The results obtained were statistically analyzed using SPSS 25.0.

RESULTS:

The result showed the highest prevalence of MSDs in the lower back, the findings of this study confirmed the work-related stress on traditional pottery makers. In the present study, the highest prevalence of musculoskeletal disorder was found in the lower back, of which had trouble in the last 12 months, 56.36% were having trouble during the last 7 days, and 19.09% were prevented from doing normal activities during the last 12 months. The prevalence of MSDs during the last 12 months revealed that the maximum of them, i.e., 24.54%, were having pain in the lower back. The present study also found MSDs prevalent in the hip joint and knee joint due to the occupational need to complete the work on prolonged squatting.

CONCLUSIONS:

This study concluded that prolonged work exposure and awkward work postural demand increase the incidence of MSD among traditional pottery makers in Bengaluru.
Characterizations of Sobolev multiplier spaces and their preduals in terms of Littlewood–Paley and Lusin area functions
Authors: Ooi Keng Hao
Published: June 2024

We characterize Sobolev multiplier spaces and their preduals in terms of Littlewood–Paley and Lusin area functions. The vector-valued and weighted norm estimates of Hardy–Littlewood maximal operator will be used as the main tools in such characterizations.
Étude archéologique diachronique de la carrière de l’Estel sud: La Bégude Reymond, Route du Pont du Gard, à Vers-Pont du Gard (30)
Authors: Vacca-Goutoulli Mireille
Published: June 2024

La carrière de l’Estel sud à Vers-Pont du Gard est située sur la rive gauche d’un méandre concave du Gardon, à 500 mètres environ à l’aval du Pont du Gard, ouvrage majeur de l’aqueduc de Nîmes construit au milieu du Ier siècle de notre ère. La carrière est reconnue pour avoir livré les blocs de grand appareil que l’on observe dans la construction du pont aqueduc. Située dans le lit majeur de la rivière, elle est abandonnée à la fin du chantier antique et le site est alors comblé et nivelé par les dépôts de crues. L’exploitation de la pierre de taille n’est rouverte qu’au XVIIIe siècle, lors de la construction du pont routier accolé à l’aval du premier étage d’arches du pont antique. Les stratégies de prévention et protection contre le risque fluvial adoptées dès l’Antiquité en raison de l’identité environnementale de la carrière, avaient préservé les traces diachroniques de l’évolution du paysage et de l’exploitation de la pierre de taille depuis l’Antiquité. Dans ce cadre, la fouille archéologique de la carrière a apporté une large vision des savoirs et des savoir-faire des carriers et des constructeurs depuis cette même période.
MSMEs Marketing Strategies Through The Use Of Social Media: A Systematic Literature Review
Authors: Ariyati Izza Milenia , Ismawati Ayu Fitria , Rizqillah Adika Iftitah , Wulandari Siti Sri , Susanti Susanti
Published: June 2024

This research aims to analyze literature regarding marketing strategies used by MSMEs in 2019-2023, as well as analyze the impact of the use of social media by MSMEs in marketing strategies. This research uses a systematic literature review method. The number of articles found was 54, which matched the criteria and keywords of this research theme. The research results show that Sinta indexes more published articles, publication trends increase yearly, and most research types use a qualitative approach. An effective marketing strategy helps increase sales for MSMEs because it can save production costs, and social media platforms become a resource that can reach consumers widely. MSME marketing strategies via social media in 2019-2023 mostly use Instagram, Facebook, and TikTok. This research can be used as a reference for future research. This research can also be used as a reference for MSME owners in implementing marketing strategies, especially social media, to improve performance through product innovation and creativity in marketing.
Parametric Stochastic Frontier Approach To Measure Efficiency Pre-And-Post-Merger Bank Syariah Indonesia
Authors: Sari Mella Katrina , Widodo Saniman , Lestari Suryani Sri , Widowati Mustika , Hasanah Siti
Published: June 2024

This research analyses the efficiency of pre-and-post-merger Bank Syariah Indonesia (BSI). This research used a descriptive quantitative analysis method. The population in this research is Islamic banks, which were merged into BSI. The sampling technique was carried out using saturated samples, resulting in the merged of three Islamic Banks, namely Bank Syariah Mandiri (BSM), Bank Negara Indonesia Syariah (BNIS), Bank Rakyat Indonesia Syariah (BRIS), to become BSI. The data used is secondary data in the form of quarterly financial reports for 2019-2022. The research focused on input variables such as total fixed assets, third-party funds, operating costs, and financing. The data analysis techniques used to measure the efficiency of Islamic banks are the Econometric Model (Single Equation Model), Stochastic Frontier Analysis (SFA), and Independent Sample t-test. The result showed that pre-merger, the total fixed asset, total third-party funds, and operating cost as the input variables of the three Islamic Banks were optimal for generating financing. Therefore, the total assets, total third-party funds, and operating costs produced a more optimal impact on the distribution of total financing. It is shown that BSI, both pre-and-post-merger, has generally been efficient in its operational activities. The results of this research complement the theory related to the efficiency level of Islamic banks in terms of the amount of financing as measured by fixed assets, total third-party funds, and operational costs. Practically, the results of this research can be a reference for banks, especially Islamic banks, that will carry out mergers to measure their efficiency level.
THE EFFECTS OF E-LEARNING ON THE UNIVERSITY EDUCATIONAL PRODUCT
Authors: Lixandru Ion-Dănut
Published: June 2024

This paper proposes the delimitation of the concept of university product from the perspective of online education, from a theoretical point of view, and tests the consequences of the transition from classical, physical, to online education. The article, from a practical point of view, is based on determining the specific factors behind the changes in higher education needs. At the same time, it seeks to determine the extent to which students who benefit from education adapt to the needs of online education; withal, the aim is to determine the degree of influence of the Internet in the decision to purchase university products or to identify purchasing decisions under different conditions. Changes in the context of the world today lead to a major change in the influence of demand for educational products, and this work demonstrates a shift in the hierarchy of elements of the marketing mix in terms of their influence on consumer decision.
THE IMPACT OF DIVERSITY ON INNOVATION : LITERATURE REVIEW
Authors: Madhi Hasan Mubarak , Salleh Hudin Dr. Norlaile binti
Published: June 2024

Innovation, cultural diversity in workplace has attracted a serious research attention over the last few years. In our paper, we have attempted to make a literature review of innovation and cultural diversity concepts and theories. First, we have looked through definitions and characteristics of diversity itself and then we have covered definitions for culture and innovation. Then, we focused on the relationship between innovation and cultural diversity. We defined that existence of foreigners in firms can influence on innovation performance, as well as that diasporas can play significant role in enhancing the innovativeness. In addition, we found from the review the high importance of city and migrant diversity for firms aiming to increase its innovativeness. Results of the literature review reveals a considerable spurt and existence of a lot of knowledge gaps in this field. The aim of this study was to provide an up-to-date and detailed review of the literature on relationship between innovation and cultural diversity.
A NOVEL META-MACHINE LEARNING APPROACH TO DIAGNOSE STRESS FROM INDIVIDUAL FACTORS USING A SELF-RETRIEVED DATASET AND THEN PROVIDE DIRECTED TREATMENT
Authors: Boina Nihal , Agarwal Jai , Agrawal Taruna , Leddo John , Napa Monish , Singhal Tanya , Muralitharan Neha , Gopinath Poorvaja , Chaubal Kinnari , Michlena Dillon , Tripathy Ashwin , Mehta Kalagee , Siddiqui Muhammad , Pasupuleti Smaran , Pasupuleti Riya , Sreedhara Aneesh , Gopinathan Asvin , Rallabandi Havish , Rachapudi Nikhit , Levkov Nate , Gatesman Alyssa , Patel Parth , Redrouthu Sathvik , Maddipatla , Jagadeepram , Gupta Vaneesha , Sonis Yash , Rudraraju Vikram , Sharma Aditya , Dhawan Aarush , Sharma Aastha , Ganne Saranya , Subash Bhargav , Tiwari Abhiraj , Sharifi Alina , Singh Soureen , Agayan Alec , Das Sauman , Jain Arnav , Goyal Utkarsh , Banerjee Saurav , Mallemudi Sadhana , Mallemudi Siddarth , Elkas Mason , Mulagura Pritham , Velaga Kavya , Jayakaran Nithya , Bachigari Shriyan , Bommineni Vedha , Karkera Sanaa , Chilukuri Sharanya , Panjabi Aaditya , Patel Jishnu , Cherukuri Vihaan , Singh Eeshika , Khan Inaayah
Published: June 2024

One of the main goals of machine learning is to make a General Artificial Intelligence. Currently, human artificial intelligence researchers work on meticulously manipulating model parameters by hand in order to arrive at highly optimized machine learning models. In the future, a system will be needed such that a software is able to completely arrive at an optimized model to a specific topic all by itself. An increasingly aware human problem is stress, which can oftentimes lead to a variety of health issues. Artificial intelligence (AI) algorithms, specifically Random Forests, have been employed to diagnose potential mental health illnesses due to a particular personal stress. Additionally, these algorithms would be manipulated by an automated hyperparameter manipulator, using extensive machine learning to find, sort, and train, validate, and test on a dataset all by itself
Techno-Economic Analysis of the Use of Wind Power Plants and Battery Energy Storage Systems as an Alternative to Lower the Cost of Diesel Power Plants
Authors: Trisnawati Fika , Sudiarto Budi
Published: June 2024

The supply of electrical energy in Indonesia is predominantly reliant on fossil fuels due to their abundant availability, ease of extraction, and lower cost. However, the continued use of fossil fuels increases CO2 emissions, contributing to the greenhouse effect. Additionally, fossil fuel prices are rising, their reserves are finite, and they require extensive replenishment time. Consequently, a transition from fossil fuels to renewable energy sources is imperative. The Indonesian government has designated Sumba Island as a pilot project under the Sumba Iconic Island (SII) program. Waingapu in East Nusa Tenggara (NTT) is notable for its significant Diesel Power Plant (PLTD) capacity of 9,450 kW, supplemented by a 2,000 kWp Solar Power Plant (PLTS). This study presents a techno-economic analysis of implementing Wind Power Plants (PLTB) and Battery Energy Storage Systems (BESS) to reduce reliance on PLTD operations. The HOMER software is utilized for system optimization, allowing for design, optimization, and evaluation from both technical and economic perspectives. Sensitivity analysis assesses the impact of fuel price increases on the optimal system configuration under current and future conditions, with a total daily energy demand of 115.6 MWh/day. The economic analysis reveals that the existing scenario has a Levelized Cost of Energy (LCOE) of $0.254/kWh. Incorporating wind turbines and BESS reduces the LCOE to $0.136/kWh. Achieving 100% renewable energy penetration with a PV-Wind-BESS configuration generates an LCOE of $0.221/kWh.
Sistem Informasi Point of Sales Berbasis Web di Perusahaan Bangunan Andalas Jaya
Authors: Chrislie Enrico , Birowo Sigit
Published: June 2024

Andalas Jaya building company is engaged in the sale of building goods or materials and transactions carried out every day are quite large, in their activities of course they require an accurate information system to make it easier to make sales transactions and record stock of goods. Making this sales and purchase information system using the Visual Studio Code program and for the database using MySQL. Researchers consider that operational activities at the Andalas Jaya Building Company are still carried out manually. Therefore, the researcher will design a Point of Sales website system to help Andalas Jaya Building Company by conducting qualitative research to get conclusions from the required sales website system. In realizing the creation of a good Point of Sales system website, researchers took the first steps such as making a system design consisting of architectural design, use case diagrams, activity diagrams, entity relationship diagrams, interface designs, website menu structures, and system implementation. With the creation of a Point of Sales website at the Andalas Jaya Building Company, it is hoped that it can help the business transaction process become more effective and efficient for further researchers to add different features.
VUK/MSUGT, TMS/TFRS ve BOBİ FRS’nin Değerleme Ölçüleri Açısından Karşılaştırılması
Authors: Yenisu Ersin
Published: June 2024

Değerleme ölçüleri işletmelerin finansal görünümlerini ve ilgili dönemin kar/zarar performansını etkilemektedir. Diğer bir ifadeyle farklı, değerleme yöntemleri işletmelerin finansal raporlamaları açısından farklı sonuçlara yol açabilir. Bu bağlamda, çalışmanın konusu muhasebe mevzuatımızdaki gelişmeler dikkate alınarak değerleme ölçülerindeki değişimi izlemektir. Dolayısıyla çalışmanın amacı muhasebe kuramı ve muhasebe uygulamaları açısından eski ve yeni değerleme yaklaşımlarını tanıtmaktır. Nitekim çalışmada, geleneksel muhasebe mevzuatı olan VUK/MSUGT, uluslararası uyum çerçevesinde kabul edilen TMS/TFRS ve muhasebe mevzuatımızdaki en güncel yaklaşımları içeren BOBİ FRS açısından değerleme ölçüleri sistematik olarak incelenmiş ve bu değerleme ölçüleri ile ilgili tanımlara, açıklamalara ve karşılaştırmalara yer verilmiştir. Bu geniş kapsamından dolayı çalışma ilgili literatürden farklılık göstermektedir. Nitel analiz yönteminin kullanıldığı çalışmada kavramsal açıklamalara, tanımlamalara ve karşılaştırmalara yer verilmiştir. Nihayetinde çalışmanın kavramsal ve karşılaştırmalı analiziyle literatüre ve uygulamacılara katkıda bulunabileceği değerlendirilmektedir.
Yabancıların Konut Talebi ile Artan Konut ve Kira Fiyatları Arasındaki İlişkinin Sorgulanması: Antalya İli Örneği
Authors: Akalın Mehmet
Published: June 2024

Türkiye’de konut ve kira fiyatlarının yükselmesi için gereken tüm koşullar çok kısa bir zaman içerisinde gerçekleşmiştir. Pandemi süreci, düşük faiz politikası, konut teşvikleri, yabancılara konut satışı, deprem felaketi ve Rusya-Ukrayna savaşı bu koşullardan bazılarıdır. Konut ve kira fiyatlarındaki fahiş artışlar neticesinde ise barınma sorununu bir kez daha ülke gündemine gelmiştir. Barınma sorununa ilişkin yapılan tartışmaların odağında, yabancıların konut talebi yer almaktadır. Bu bağlamda, Antalya’da son zamanlarda oluşan yüksek konut ve kira fiyatları, bölgede yaşayan yabancılara karşı bir tepkinin yükselmesine sebep olmuştur. Bu çalışmada, Antalya’daki konut ve kira fiyatlarında yaşanan yükselişin asıl nedeninin ne olduğu ortaya koyulmaya çalışılmıştır. Bunun için de bölgede “yabancıya konut satışının, konut ve kira fiyatlarını arttırdığı” şeklindeki fenomenin doğru olup olmadığı tespit edilmek istenmiştir.
Midiendo la realidad: El papel de las variables en la investigación científica
Authors: Mancilla Barillas Mario René
Published: June 2024

OBJETIVO: Describir qué son las variables, su función general y cómo se relacionan con el diseño teórico y la realidad observable, así como presentar una clasificación de las mismas. MÉTODO: Mediante una revisión de literatura se identifica, sistematiza y explica la función de las variables en la investigación científica. RESULTADOS: Se demuestra que las variables son poco estudiadas o explicadas en las fuentes académicas pero que son esenciales para la producción de conocimiento científico y para posibilitar la transición entre el diseño de la investigación teórico y la investigación empírica. CONCLUSIÓN: Las variables son elementos esenciales de la investigación científica. Son características, atributos o propiedades de un objeto de estudio que pueden variar y que pueden ser medidas, observadas, comparadas o interpretadas con el objeto de estudiar la realidad. Sin un conjunto de variables bien construidas y coherentes con el problema, objetivos e hipótesis la investigación científica es inviable.
Sanat-Siyaset İlişkisi Bağlamında Türkiye'de Politik Tiyatro: Ortaoyuncular Ekibinin Oyunlarının İncelenmesi
Authors: Karhan Ahmet Can
Published: June 2024

SSanat ve siyaset tüm dünyada olduğu gibi Türkiye’de de birbirini birçok yönden etkilemiştir. İstibdat dönemi, Cumhuriyetin ilk yılları ve darbe dönemleri gibi zamanlarda siyasetin sanat üzerinde belirleyiciliği olurken, 1960-1970’li yıllarda ve Turgut Özal döneminin başlamasıyla sanatın belirleyici olma özelliği daha belirgin hale gelmeye başlamıştır. Bu dönemlerde sanatın temel konusu güncel politik olaylar olurken, birçok muhalif tiyatro grubu iktidarların politikalarına yönelik eleştirilerini tiyatro sahnesinden yansıtmıştır. Ferhan Şensoy tarafından kurulan Ortaoyuncular tiyatro ekibi, 1980’li yıllarla birlikte Türkiye’nin yaşadığı neoliberal dönüşümlerin etkilerini birçok açıdan eleştirel bir üslupla dile getirmiştir. Bu çalışma, dönüşüm döneminin bir eleştirisi olarak sahnelenen “İstanbul’u Satıyorum” ve “Kahraman Bakkal Süpermarkete Karşı” oyunlarını içerik analizi yöntemiyle incelemektedir. Çalışma, her iki oyunun politik tiyatronun ve epik tiyatronun birçok özelliğini taşımakta olduğunu ve tiyatro metinlerinin yazarının dönemin siyasi isimlerini ve olaylarını birer komedi unsuru haline getirerek eleştirdiğini ortaya koymaktadır.
New technologies and enforced disappearances: opportunities and challenges for the protection of human rights
Authors:   Institute for Human Rights – North Macedonia, Stefanovska Vesna
Published: June 2024

New technologies and enforced disappearances have been part of thematic study included in the annual report of the Working Group on Enforced and Involuntary Disappearances (WGEID) published in August 2023. Enforced disappearances present flagrant human rights violation where the families of disappeared person are not familiar with the fate and whereabouts of their disappeared relatives. The use of new technologies in cases of enforced disappearances may enhance the human rights protection, facilitate the search for disappeared persons and obtain evidence. However, new technologies can be used to prevent further investigations and obtain evidence especially in cases where torture is committed by state actors and cases of enforced disappearances in transnational context. This paper will analyze the positive and negative effects from the use of new technologies in enforced disappearances and will emphasize the importance to conduct an effective investigation and to acknowledge the right to truth in these cases.
CERTAIN BILINEAR GENERATING RELATIONS FOR THE EXTENDED GAUSS HYPERGEOMETRIC FUNCTION, USING FRACTIONAL CALCULUS
Authors:   Departmentof Mathematics and Statistics, Dr. Rammanohar Lohia Avadh University Ayodhya, India., Kumar Shukla Pankaj , Raizada S. K. ,   Departmentof Mathematics and Statistics, Dr. Rammanohar Lohia Avadh University Ayodhya, India.
Published: June 2024

The main aim of the present paper is to apply the extended Riemann Liouville fractional derivative operator for finding some bilinear generating relations for extended Gauss hypergeometric function. Two main results are obtained, which are presented in the form of two theorems.
Dermal Autografts in Plastic Surgery: Advances, Techniques, and Clinical Outcomes
Authors:   Hospital general de zona 3, Instituto Mexicano del Seguro Social. Aguascalientes, Aguascalientes, México., Torres Lisset Guadalupe Hernández , Contreras Atziri Verenice Sánchez ,   Hospital general de zona 2, Instituto Mexicano del Seguro Social. Aguascalientes, Aguascalientes, México., Acoltzi Josue Hernandez ,   Unidad de salud IMSS Bienestar Huiloac, Tlaxcala, Mexico., Avila María Guadalupe Cuecuecha ,   Universidad Popular del Estado de Tlaxcala, Mexico.
Published: June 2024

The utilization of dermal autografts in plastic surgery has evolved significantly over the past few decades, offering a versatile and reliable method for the reconstruction of various tissue defects. This article reviews the current advancements in dermal autografting, with a focus on the latest surgical techniques, integration with regenerative medicine, and the clinical outcomes observed in diverse patient populations. We discuss the biological basis of autograft survival and integration, highlight innovative approaches to enhance graft viability, and analyze complications associated with these procedures. The article also explores the role of autologous dermal grafts in aesthetic and reconstructive surgery, providing insights into future directions for research and clinical practice.
Growth of Islamic Fintech in Indonesia
Authors:   Faculty of Economic and Business, Universitas Widyatama, Bandung, Indonesia, Ayu Effendi Kharisya , Wahju Widajatun Vincentia ,   Faculty of Economic and Business, Universitas Widyatama, Bandung, Indonesia
Published: June 2024

Islamic fintech is the latest breakthrough in finance that combines finance and technology using Islamic principles. Opportunities in developing Islamic fintech in Indonesia are also very wide open considering the large population of Indonesia who are Muslims. This research has two main objectives. The first objective of this study is to determine whether there is a difference between Islamic fintech and conventional fintech. The second and third objective is to determine whether Islamic fintech and conventional fintech affect economic growth in Indonesia. Independent T-test analysis is used to test the first objective, while regression analysis is used in this research method to test the second and third objectives. This research is a type of quantitative research. The data used is monthly time series data from January 2019 to December 2022. This research concludes that there are substantial differences between sharia and conventional fintech. This difference is caused by the large difference in the number and scale of sharia and conventional fintech businesses, namely 2%:98%. The impact of sharia fintech on Indonesia's economic growth is very small. The reason is that Sharia fintech in Indonesia is not yet operating optimally due to several obstacles. Apart from that, Indonesia's economic growth is greatly influenced by conventional fintech. This is due to the large number of assets and businesses which contribute 98% of total fintech assets
Green Financial Management, Firm Size, and Capital Structure: Practical Implications for Financial Performance of Companies in the SRI-KEHATI Index
Authors:   University of Jember, Jember, Indonesia, Hudiani Sholeha Novia , Awwaliyah Intan Nurul ,   University of Jember, Jember, Indonesia, Mufidah Ana ,   University of Jember, Jember, Indonesia, Sumani Sumani ,   University of Jember, Jember, Indonesia, Puspitasari Novi ,   University of Jember, Jember, Indonesia
Published: June 2024

The company's efforts to improve financial performance through maximizing profits are not accompanied by the company's concern for the impacts caused, so there are regulations that require companies to commit to carrying out sustainable business practices and care about environmental issues by implementing green financial management. The indepen dent variables in this study are green financial management, firm size, and capital structure, while the dependent variable in this study is financial performance. This study aimed to test and analyze the effect of 1) green financial management on financial performance, 2) firm size on financial performance, and 3) capital structure on financial performance. The population in this study are all companies incorporated in the SRI-KEHATI index for 2017-2022. Sampling was carried out using the purposive sampling method. The data analysis method is a multiple linear regression analysis process using SPSS 26 software. The results showed that partially green financial management and capital structure significantly positively affect financial performance. Firm size has an insignificant effect on financial performance.
Article RETRACTED due to manipulation by the authors Effective Verbal Communication in Physical Education Learning and Sports Coaching to Improve Achievement and Health: A Systematic Review
Authors: Charlina Charlina , Roziah Roziah , Ismail Syofianis , Piliang Wilda Srihastuty Handayani , Siswanto Siswanto , Setyawan Hendra , Zulbahri Zulbahri , Darmawan Arief , Shidiq Abdul Aziz Purnomo , Eken Özgür , Pavlovic Ratko , Latino Francesca , Tafuri Francesco
Published: June 2024

This systematic review aims to provide in-depth information regarding effective verbal communication in physical education learning and sports coaching to improve achievement and health. The literature review was conducted identifying, evaluating, and interpreting relevant research results. To collect data, an online search was performed using Scispace software, focusing on journals indexed by the Scopus database, DOAJ, and published between 2019 - 2024. The journals were selected based on inclusion criteria: international and national journals indexed by Scopus, DOAJ, and Sinta. The keywords used were; "Effective Verbal Communication", "Physical Education Learning", and "Sports Coaching". The search generated 95 articles. Other 7 registered articles were also obtained from other sources using the inclusion criteria determined beforehand. These articles then went through a screening process, and 10 articles were selected as they matched the theme and the inclusion requirements. For standard operationalization, this research follows the PRISMA method. The research six main results. First, (1) Good verbal instructions from trainers or teachers were proven to improve the quality of students' understanding, motivation, and level of physical activity. They had a positive impact on achievement and fitness or physical health. Besides personal benefits, effective verbal communication was known to improve interpersonal relations, cooperation, coordination, and team performance among students and athletes. This study also found that encouragement of verbal communication helps adolescent students understand sports rules and techniques, improve physiological reactions and skills, and improve physical fitness and performance. Fourth, verbal communication in Indonesian facilitated active participation, teacher-student interaction, increased understanding and safety of athletes, and preserved positive cultural values ​​in sports. Next, it was found that good use of Indonesian in sports training encouraged proper understanding and improved performance and safety in sports activities. Finally, this study noted several obstacles faced by physical education teachers. However, these challenges can be overcome by incorporating communication strategies that use modern technology to encourage student activity and the effectiveness of physical education learning.
Keywords: Verbal Communication, Physical Education, Sports Coaching