bluuebunny/crossref_metadata_2025 huggingface dataset:
Allusive proper names as a means for expressing content-related and subtext information in English-language literary texts (based on the text of the novel “The Magus” by John Fowles)
Authors: Ananyina Marina Aleksandrovna
Published: December 2023

The study aims to identify the ways of presenting content-related and subtext information when using allusive proper names in literary texts. The research is based on the text of John Fowles’s novel “The Magus”. The paper considers modern approaches to the notion of subtext, one of the types of information in the text along with substantive-factual and substantive-conceptual information. The allusive proper name is considered as one of the means of subtext expression. The paper analyzes the features of content-related and subtext information, demonstrates a correlation between the notions of presupposition, implication, subtext and allusion and examines philologists’ points of view regarding the terms related to allusion. The scientific originality of the study lies in the fact that it considers the allusive proper name as one of the means of subtext expression, namely such types of content-related and subtext information as rational-logical, artistic-aesthetic and cultural-historical information, which are manifested at the explicit and implicit levels of a literary text, while subtext can contain both explicitly and implicitly expressed elements making it easier for the reader to decode information. The allusive proper name acts as a means of subtext and implicitness expression. The results of the study include the following. Subtext is characterized by psychological and explicit-implicit nature of expression. The following options are possible for presenting information through language signs and an associative background. A part of the information of subtext is represented explicitly by linguistic units in the context, the rest of the information is not represented in the formal plane of the text, but can be restored based on the analysis of explicitly represented linguistic units. Six types of correlation between explicit/implicit information contained in a literary text, namely artistic-aesthetic, rational-logical and cultural-historical information, have been identified.
The category of comparison as an object of linguistic research: A theoretical and analytical review
Authors: Atlashova Irina Andreevna , Klyushina Alena Mikhailovna
Published: December 2023

The aim of the study is to carry out a theoretical and analytical review of modern academic works on the category of comparison in Russian and foreign linguistics in the 21st century. The material of the paper is of topical nature and demonstrates contradictory views on the development of scientific knowledge about the category of comparison. The scientific novelty of the study lies in presenting the results of the research on the topical issues of the category of comparison in Russian and foreign linguistics in the 21st century. The results of the review and analysis of the academic works devoted to the category of comparison make it possible to confirm the relevance and novelty of investigating the category of comparison in modern English, in addition, the findings represent a necessary basis for conducting a comprehensive description of the linguistic phenomenon under consideration and also allow researchers to supplement scientific knowledge about the problems of the functional-semantic category of comparison in modern English.
Intermedial techniques of representing an artist’s image in the stories “Glittering Pie” by H. Miller and “A Working Day” by Ch. Bukowski
Authors: Markovnenkov Dmitry Victorovich
Published: December 2023

The aim of the study is to identify the intermedial means involved in depicting the image of a creative personality represented in the stories “Glittering Pie” (1935) by H. Miller and “A Working Day” (1972) by Ch. Bukowski, contributing to their interpretation, which will cover the works plot-wise, texturally and epistemologically. The study is original in that it is the first to compare H. Miller’s and Ch. Bukowski’s stories from an intermedial perspective. The way in which different visual media techniques find their embodiment in a literary text, being present in it not only as a static reference, but also as an active component influencing the formation of writing and images, is of particular interest in the analysis of the works. The visual in Miller’s story manifests itself through the techniques of surrealism, impressionism and cinema. In the case of Bukowski’s story, the visual is realized through the forms of pop art, photographic stylization and a reference to the subjects of paintings by the artist E. Hopper. The results show that the intermedial techniques involved in the stories make it possible to determine the writers’ connection with the aesthetic projects of modernism and postmodernism. While Miller’s story shows the features of modernist art associated with self-reflection, originality of creative vision and the gap between the ordinary and the sacred, in Bukowski’s story, there are certain features of postmodernism represented by symbolic reduction, a decrease in aesthetic pathos around the artist and his creative activity, as well as thematization of everyday life and banality.
Russian urbanonymy and its lexicographic representation: Problems and prospects
Authors: Razumov Roman Viktorovich
Published: December 2023

The aim of the research is to substantiate the concept of creating a composite dictionary of urbanonyms of the Russian Federation, accumulating information about the most frequent inner-city names, the time of their occurrence, the existing variants of onyms, to identify a range of problems facing this project. The absence of such a publication significantly hinders regional studies of urban toponymy. The scientific novelty lies in elaborating the concept and principles of compiling a dictionary of urbanonyms of the Russian Federation, the proposed model of the structure of a dictionary entry reflecting the main linguocultural features of the names of inner-city objects of the Russian Federation. The paper substantiates the need to develop a composite reference book on the urban toponymy of the country, indicates sources of information about the time of creation of names in various localities, provides the composition of the basic corpus, describes the principles of selection of urbanonyms. The author has developed the structure of a dictionary entry, has given examples of the dictionary entries ‘Sovetskaya Street/Avenue/Square’ and ‘Lenina Street/Avenue/Lane/Drive/Square’. The research findings have shown that the preparation of a composite dictionary of the Russian urbanonymy of the Russian Federation will make it possible to describe the main body of pre-revolutionary and modern urban toponyms and choronyms of the country, identify federal and regional trends in their development, highlight the main periods of occurrence, possible causes of creation and loss.
Characteristics of the Acute Phase Inflammatory Marker — C-Reactive Protein in Patients with Chronic Bronchial Affections
Authors: Shevchuk–­Budz U.I.
Published: December 2023

Chronic lung diseases, particularly those affecting the bronchial tree, are a leading cause of disability and mortality worldwide. This emphasizes the importance of addressing issues related to the prevention, timely detection and treatment of conditions such as chronic bronchitis (CB), chronic obstructive pulmonary disease (COPD) and COPD with bronchiectasis. The use of highly sensitive methods for monitoring likely exacerbations and predicting the development of comorbidities in this patient cohort is justified.
Objective — to study the nature and severity of changes in the acute phase inflammatory marker — C-reactive protein (CRP) in patients with chronic lung diseases.
Materials and methods. A total of 62 hospitalized patients with CB, COPD and COPD with secondary bronchiectasis were examined. All patients underwent clinical, laboratory and instrumental investigations. The serum CRP level was measured in peripheral blood. A control group comprised 15 practically healthy individuals.
Results and discussion. It was found that chronic inflammatory lung diseases were more prevalent in men (in the CB group — 55.0 %, in the COPD group — 86.96 %, in the COPD with secondary bronchiecta­sis group — 93.7 %). The CRP level in peripheral blood serum was elevated in all groups: in the CB group — (5.5 ± ± 0.12) mg/l, in the COPD group — (7.54 ± 0.98) mg/l, in the COPD with secondary bronchiectasis group — (12.93 ± 1.23) mg/l. This indicator was statistically significantly higher by 4.0, 5.6, and 9.6 times, respectively (all p < 0.001) compared to the control group. The proportion of smokers was 60.0 % in the CB group, 73.9 % in the COPD group and 78.94 % in the COPD with secondary bronchiec­tasis group.
Conclusions. Harmful habits, especially smoking, contribute significantly to the widespread occurrence of chronic lung diseases. Exacerbations and progression of chronic inflammatory processes in the bronchial tree are associated with an elevated level of CRP. The level of CRP significantly increases with the development of concomitant changes, particularly the presence of secondary bronchiectasis. There is a correlation between smoking and the severity of chronic inflammatory lung diseases, as well as a relation­ship between the severity of COPD and the duration of smoking.
Peculiarities of Metabolism and Cardiac Electrical Activity in Patients with Chronic Obstructive Pulmonary Disease and Coronary Heart Disease in the Presence of Metabolically-Associated Liver Steatosis
Authors: Komarytsia O.Y. , Pylypiv L.I. , Radchenko O.M.
Published: December 2023

While the development of specific steatohepatitis-associated cardiomyopathy (SHACMP) in the context of fatty liver disease has been documented, it remains unclear whether any cardiac changes occur during the initial stage of fatty liver disease, known as metabolic-associated liver steatosis (LS).
Objective — to evaluate the characteristics of metabolism and electrical activity of the heart in patients with chronic obstructive pulmonary disease and chronic forms of coronary heart disease and concomitant liver steatosis.
Materials and methods. 35 patients with chronic obstructive pulmonary disease, respiratory insufficiency stages I and II, coronary heart disease, atherosclerotic cardiosclerosis, and heart failure functional classes I and II, were examined. Their diagnosis and treatment were conducted in accordance with established protocols and international recommendations. Depending on the occurrence of LS, patients, matched for age, gender and lung function parameters, were divided into two groups: those suffering from it (n = 26) or not suffering from it (n = 9). Additionally, leptin level was determined, body mass index (BMI), leptin to BMI ratio, De Ritis ratio, hepatic steatosis index, glomerular filtration rate (according to MDRD) were calculated, and automatic ECG test was run. The results were processed statistically; the significance assumed at р < 0.05.
Results and discussion. It was established that LS was diagnosed in patients with a higher BMI and was accompanied by clear metabolic changes — higher values of leptin, leptin-to-BMI ratio, fasting blood glucose and total cholesterol levels. The criteria of LS are not only an increase in echogenicity and size of the liver, but also higher values of ALT, De Ritis ratio and hepatic steatosis index. According to the correlation analysis, the deterioration of the liver condition was accompanied by changes in the heart — tachycardia and a decrease in the angle of the QRS complex, which can be considered as signs of the development of SHACMP, characteri­zed by a prolongation of the PQ interval (р = 0.07) and a significant deviation of the angle of the QRS complex. Inflammation and endogenous intoxication are the leading mechanisms of progression of both LS and SHACMP.
Conclusions. Patients with chronic obstructive pulmonary disease and chronic forms of coronary heart disease, alongside with liver steatosis, exhibit signs of steatohepatitis-associated cardiomyopathy caused by metabolic changes, inflammation and endogenous intoxication.
Video-Thoracic Surgical Treatment of TB-Empyema for Pleuro-Pulmonary Tuberculosis
Authors: Koshak Yu.F.
Published: December 2023

According to WHO, the emergence of purulent diseases with superinfection is observed due to the formation of resistance of microorganisms, mixed specific and nonspecific flora to the main anti-tuberculosis drugs. The rational choice of diagnosis and surgical intervention significantly reduces the formation of suppuration resistance for pleura-pulmonary tuberculosis.
Objective — to improve the surgical treatment of pleural tuberculosis empyema due to minimally invasive diagnostics and video-assisted thoracic resections.
Materials and methods. A retrospective analysis was conducted on our own studies involving 685 cases of patients with stage I—III pleuro-pulmonary complications of tuberculosis empyema. This included a review of minimally invasive video-surgical diagnostics and operations conducted over the past decade. The treated patients were divided into two groups: Group 1, consisting of 351 patients (51.25 %), underwent operations using minimally invasive technologies (video-thoracoscopy (VTS), video-assisted surgical resection (VATS)); Group 2, comprising 334 patients (48.75 %), underwent open wide thoracotomy. In Group 1, 301 patients had acute pleural TB-empyema and 50 had chronic cases. Among the patients in Group 2, acute pleural TB empyema was observed in 284 cases and chronic TB empyema in 50 cases.
Results and discussion. According to our data, only VTS is a highly informative method for detecting tuberculosis, pleural TB-empyema in the 1st, 2nd and 3rd stages of its development. Minimally invasive technologies have advantages over open thoracotomies and significantly reduce intraoperative bleeding, the number of posto­perative complications and mortality from surgical treatment. The analysis of our own researches proves that video­thoracoscopic interventions (VTS, VATS) in tuberculous suppurations have some disadvantages, namely: the inability to palpably assess the condition of altered structures within the pleural cavity, the technical complexity involved in performing marginal resection of a bronchial fistula. All this requires further development of high-tech surgical techniques in our country. In a comparative analysis of the frequen­cy and nature of complications during surgery, we found that, overall, in the main group, they occurred 2.1 times less frequently than in the comparison group (p < 0.05).
Conclusions. To improve surgical treatment of pleural tuberculosis empyema through minimally invasive diagnostics and video-assisted thoracic resections (VATS). The greatest diagnostic difficulties were encountered in patients with localization of pleural TB empyema in the area of active tuberculous and metatuberculous changes. In 48.7 % of patients, the pleural TB empyema is diagnosed at a late stage of the purulent process.
Prospects for the use of Lipster Mint cream in the complex treatment of herpes zoster
Authors: Shevchenko O.P. , Bardov P.V. , Razdaibiedin S.N.
Published: December 2023

Objective — to investigate the clinical efficacy of Lipster Mint cream in the complex treatment of patients with herpes zoster.

Materials and methods. The study included 15 patients (11 women and 4 men) with acute herpes zoster. The age of the patients ranged from 38 to 70 years. The patients had severe clinical symptoms (typical vesicular rash, itching of varying intensity, burning sensation, intense pain along the affected nerves and sleep disturbance). The localization of pathological foci was unilateral: in 12 patients on the skin of the trunk, in 1 patient on the buttock and in 2 patients on the skin of the thigh. All patients reported a decrease in quality of life due to the disease. The complex treatment included Valavir, one of the valacyclovir drugs, according to the recommended regimens, which was administered orally in 1000 mg tablets three times a day for 7 days. Acute herpes-associated pain and heartburn were relieved with analgesics and topical application of Lipster Mint cream, manufactured by Farmak (Ukraine), which contains acyclovir 5 % and menthol. A distinctive advantage of Lipster Mint is that it contains the highest dose of acyclovir permitted for topical products — 5 %, as well as menthol which cools and reduces itching. The effectiveness of treatment of herpes zoster was assessed by the dynamics of clinical symptoms and subjective feelings on the 2nd, 5th and 10th days of treatment.

Results and discussion. As a result of the treatment, positive dynamics of all clinical manifestations was achieved. Inflammatory phenomena such as swelling and hyperemia of the skin significantly decreased, the appearance of fresh herpes rash stopped within 24 hours, body temperature normalized on the 2—3rd day, general condition improved, pain and discomfort in the affected areas significantly decreased, partial epithelialization of erosions and the appearance of crusts were observed on the 5—7th day. With the topical application of Lipster Mint, under the influence of menthol, from the first minutes of application, patients significantly reduced the sensations of burning, tingling and pain in the areas of skin lesions.

Conclusions. Despite the available arsenal of specific and non-specific antiherpetic drugs, treatment of patients suffering from herpes zoster continues to be an urgent medical problem that requires further improvement and individualized approach. Our clinical observations indicate the effectiveness of the systemic drug Valavir and the topical drug Lipster Mint cream in the complex treatment of herpes zoster, which makes it possible to reduce postherpetic neuralgia in the areas of skin lesions and improve the quality of life of patients.
The Role of the Microbiome in Inflammation and Carcinogenesis
Authors: Jabłońska-Trypuć Agata
Published: December 2023

Inflammation has been confirmed to exist in the tumor microenvironment, while the risk of cancer occurrence increases in cases of chronic inflammation. It is estimated that approximately 10% to 20% of cancers are associated with chronic infections and attendant inflammation. Bacteria, both pathogenic and commensal, viruses, and fungi actively participate in the development and maintenance of inflammation and tumor growth in humans. The exposome, which is a sum of human environmental exposures, such as industrial diet, consumed drugs, and toxins, affects the composition and function of the human microbiome, which could lead to dysbiosis and disorders in tissue homeostasis through different mechanisms, including the intensification of the immune response, activation and abnormal proliferation, and disruption to epithelial barrier integrity. Presently, science remains at the stage of revealing the complexity associated with the mechanisms involved in building relationships that cover the microbiome–inflammation–tumor, yet it is already known how important it is to care for microbial homeostasis of the organism.
Kv1.3 Blockade Alleviates White Matter Injury through Reshaping M1/M2 Phenotypes via the NF-κB Signaling Pathway after Intracerebral Hemorrhage
Authors: Wang Bo , Chen Jie , Wang Shuhong , Chen Lin , Zhang Xuyang , Zhou Tengyuan , Zhong Jun , Zhang Chao , He Yijia , Zuo Yonglin , Feng Hua , Yin Yi , Ge Hongfei
Published: December 2023

Background: White matter injury (WMI) in basal ganglia usually induces long-term disability post intracerebral hemorrhage (ICH). Kv1.3 is an ion channel expressed in microglia and induces neuroinflammation after ICH. Here, we investigated the functions and roles of Kv1.3 activation-induced inflammatory response in WMI and the Kv1.3 blockade effect on microglia polarization after ICH. Methods: Mice ICH model was constructed by autologous blood injection. The expression of Kv1.3 was measured using immunoblot, real-time quantitative polymerase chain reaction (RT-qPCR), and immunostaining assays. Then, the effect of administration of 5-(4-Phenoxybutoxy) psoralen (PAP-1), a selectively pharmacological Kv1.3 blocker, was investigated using open field test (OFT) and basso mouse score (BMS). RT-qPCR, immunoblot, and enzyme-linked immunosorbent assay (ELISA) were taken to elucidate the expression of pro-inflammatory or anti-inflammatory factors around hematoma. PAP-1’s function in regulating microglia polarization was investigated using immunoblot, RT-qPCR, and immunostaining assays. The downstream PAP-1 signaling pathway was determined by RT-qPCR and immunoblot. Results: Kv1.3 expression was increased in microglia around the hematoma significantly after ICH. PAP-1 markedly improved neurological outcomes and the WMI by reducing pro-inflammatory cytokine accumulation and upregulating anti-inflammatory factors. Mechanistically, PAP-1 reduces NF-κB p65 and p50 activation, thus facilitating microglia polarization into M2-like microglia, which exerts this beneficial effect. Conclusions: PAP-1 reduced pro-inflammatory cytokines accumulation and increased anti-inflammatory factors by facilitating M2-like microglia polarization via the NF-κB signaling pathway. Thus, the current study shows that the Kv1.3 blockade is capable of ameliorating WMI by facilitating M2-like phenotype microglia polarization after ICH.
Divisive or Descriptive?: How Americans Understand Critical Race Theory
Authors: Safarpour Alauna , Trujillo Kristin Lunz , Green Jon , Pippert Caroline H , Lin Jennifer , Druckman James
Published: December 2023

Critical Race Theory (CRT) has become a flashpoint of elite political discord, yet how Americans actually perceive CRT is unclear. We theorize that Republican elites utilized a strong framing strategy to re-define CRT as an “empty signifier” representing broader racial and cultural grievances. Using a survey and a pre-registered experiment among US adults (N=19,060), we find that this strategy worked. Republicans exhibit more familiarity with CRT and hold more negatively valenced (and wide ranging) sentiments toward CRT, relative to Democrats. Moreover, compared to teaching the legacy of racism in schools, Republicans are significantly more opposed to teaching CRT while Democrats express greater uncertainty. Our findings suggest that by framing CRT as a broad term that envelopes many grievances (including those beyond the scope of CRT), Republicans have shaped a subset of Americans’ understanding of and attitudes towards CRT.
Fraud Deterrence: The Management’s Intention In Using FCP
Authors: Koerniawan Koenta Adji , Afifah Nunuy Nur , Sueb Memed , Suprijadi Jadi
Published: December 2023

The Indonesian Government Regulation on the Government's Internal Control System (GICS / SPIP) is also applied to the Regional Public Service Bodies of Hospitals (RPSB), but ironically many cases of fraud occur in regional hospitals. Fraud Control Plan (FCP), which is the second layer of reinforcement after GICS, is needed to deter fraud. The concept of fraud deterrence, used in the International Standards on Auditing (ISA), is different from fraud prevention, but both are translated the same today. As a novelty, this study proposes a new definition of fraud deterrence and the D.E.T.E.R.E. This study uses the theory of planned behavior and aims to confirm the relationship between understanding of GICS, attitude towards behavior (ATB), subjective norm (SN), perceived behavioral control (PBC), on management's intention to use FCP to deter fraud and its implications for fraud deterrence. The research sample is 151 management people who work in hospitals. The analysis method uses SEM-Lisrel. The results showed that understanding of GICS and SN had a positive effect on management's intention to use FCP to deter fraud. Management's intention to use FCP to deter fraud has a positive effect on fraud deterrence.
Coarse descriptions, microcanonical ensembles and the Born rule
Authors: Review Blind
Published: December 2023

It is conventionally thought that a large macroscopic object (universe) converges to a microcanonical ensemble. We ask how the microcanonical ensemble assumption can be consistent with the initial system amplitude information preserved (usually in the diagonal entries of the system density matrix) in a quantum measurement process. Patching these two assumptions together, as well as interpreting the initial system state and the microcanonical ensemble as reflecting epistemic uncertainty and providing a coarse description, results in the Born rule.
EVEN SMALL DIFFERENCES IN ATTRACTIVENESS AND FORMIDABILITY AFFECT THE PROBABILITY AND SPEED OF SELECTION: AN ONLINE STUDY AND AN OFFLINE REPLICATION
Authors: Třebický Vít , Tureček Petr , Třebická Fialová Jitka , Pátková Žaneta , Grygarová Dominika , Havlicek Jan
Published: December 2023

Facial and bodily features represent uniquely salient visual stimuli upon which people spontaneously attribute various fitness-relevant characteristics such as attractiveness or formidability. While existing evidence predominantly relies on sequential stimuli presentation tasks, real-world social comparisons often involve assessing two or multiple individuals. In studies using two-alternative forced-choice tasks, participants usually perform at rates above the chance to select the expected option. However, these tasks use dichotomized and artificially manipulated stimuli lacking generalizability to situations where the differences between individuals are less likely ‘clear-cut’. In two registered studies comprising online (N = 446) and onsite (N = 56) participants, we explored the influence of the degree of difference in attractiveness and formidability between stimuli pairs on both the probability of selection and selection speed. Participants were presented with randomly selected pairs of men (30 pairs of faces, 30 pairs of bodies) and tasked with choosing the more attractive or formidable target.Applying Bayesian inference, our findings reveal a systematic impact of the degree of difference on both the selection probability and speed. As differences in attractiveness or formidability increased, both men and women exhibited a heightened propensity and speed in selecting the higher-scoring stimuli.Our study demonstrates that people discriminate even slight differences in attractiveness and formidability, indicating that cognitive processes underlying the perception of these characteristics had undergone selection for a high level of discrimination.
PENINGKATAN KOMPETENSI EMKM DAN BUMDES: PELATIHAN DAN PENDAMPINGAN AKUNTANSI KEUANGAN DI WILAYAH CIGANITRI, KABUPATEN BANDUNG
Authors: Koerniawan Koenta Adji
Published: December 2023

The empirical fact that is currently happening is that EMKM and BUMDES entrepreneurs in the Ciganitri area do not understand what and how financial reports are presented according to standards. The implication is that they cannot give financial reports, so the financial position of the business cannot be determined accurately, as a result, the assessment of financial performance fails, and tax reporting cannot be determined precisely. Increasing competence in financial accounting through training and mentoring is an urgent solution. This activity was attended by 25 participants from various EMKM and BUMDES business units. This abdimas aims to help EMKM and BUMDES entities understand basic finance and introduce the use of the Si Apik and SIABDES accounting applications for preparing financial reports according to EMKM financial accounting standards (SAK). The methods used in Community Service include problem identification, field surveys, training, post-training assistance, and assessments, to measure the achievement of community service outcomes. The results obtained show an increase in the understanding of the Community Service participants. They are starting to be interested in applying the Si Apik accounting application or SIABDES for the purpose of presenting financial reports according to standards so that their obligations in realizing transparency and accountability can be helped to be realized.
Harmonizing Government Responses to the COVID-19 Pandemic
Authors: Cheng Cindy , Messerschmidt Luca , Bravo Isaac , Waldbauer Marco , Bhavikatti Rohan , Schenk Caress , Grujic Vanja , Model Tim , Kubinec Robert , Barceló Joan
Published: December 2023

Public health and safety measures (PHSM) made in response to the COVID-19 pandemic have been singular, rapid, and profuse compared to the content, speed, and volume of normal policy-making. Not only can they have a profound effect on the spread of the virus, but they may also have multitudinous secondary effects, in both the social and natural worlds. Unfortunately, despite the best efforts by numerous research groups, existing data on COVID-19 PHSM only partially captures their full geographical scale and policy scope for any significant duration of time. This paper introduces our effort to harmonize data from the eight largest such efforts for policies made before September 21, 2021 into the taxonomy developed by the CoronaNet Research Project in order to respond to the need for comprehensive, high quality COVID-19 data. In doing so, we present a comprehensive comparative analysis of existing data from different COVID-19 PHSM datasets, introduce our novel methodology for harmonizing COVID-19 PHSM data, and provide a clear-eyed assessment of the pros and cons of our efforts.
Salt Precipitation during Geological CO2 Storage: Effect of Access to Continuous Brine Source
Authors: Masoudi Mohammad , Nooraiepour Mohammad , Hellevang Helge
Published: December 2023

During CO2 storage, the near-wellbore environment experiences significant chemical, physical, thermal, and mechanical perturbations. Therefore, it is crucial to characterize the coupled thermo-hydro-mechanical-chemical (THMC) processes in this region through representative experimental tests and numerical simulations to maximize the safety and cost-efficiency of CO2 storage. One common shortcoming of current experimental methods is failing to facilitate access and replicate the in-situ brine sources within geological repositories, particularly saline aquifers. This failure can significantly alter the dynamics and dimensionality of mineral/crystal growth in porous reservoir rocks due to the availability and continuity of solute. To address this issue, we designed surface mineral precipitation tests and large-scale sandbox experiments to investigate salt precipitation and growth under two different scales and regimes in porous geometries. The laboratory results indicated massive salt accumulation close to the injection port and underlined the effect of solute availability and continuity on intensifying severity of salt accumulation. The observed continued growth highlights the importance of designing representative laboratory experiments in exploring fluid-rock interactions during carbon sequestration in the subsurface geological media.
Effects of Bilingualism, Household Size and Siblings on Theory of Mind Development in Pakistani and British Children
Authors: Mazhar Anushay , Ellis Katherine , Moss Joanna , White Sarah Joanne
Published: December 2023

The development of a Theory of Mind (ToM) is a critical milestone observed in early childhood. There is evidence of diversity in how children from different social and cultural contexts develop ToM, but a dearth of research exploring how inter- and intra-country factors overlap. Factors associated with ToM development, which vary within countries, may also contribute to cross-country differences, such as bilingualism, siblings numbers and household size. Here, we explore the effect of country, bilingualism, household size and number of siblings on the development of children’s ToM after controlling for receptive vocabulary and age, in Pakistani and British children. Bilingualism and country were both independent predictors of children’s ToM development, whilst household size and number of siblings did not explain further variance in ToM. Together, these findings illuminate the role of the linguistic environment in different ToM developmental trajectories and highlight the importance of considering both inter- and intra-cultural factors.
The Challenges Ahead: Concepts, Analytics, and Ethics of Value-Based Care in Applied Behavior Analysis
Authors: Cox David J.
Published: December 2023

Value-based care has incrementally increased its footprint across healthcare over the past two decades. Recently, several organizations in ABA have begun experimenting with various components of value-based care specific to the delivery of ABA services and it seems likely that this trend will continue into the future. For those new to value-based care, this manuscript reviews the main conceptual components as well as common myths and misconceptions about value-based care. Though conceptually straightforward, practically pulling off value-based care in ABA will require significant advancements in data collection, analytics, sharing, and transparency that follow from broad field-wide collaboration. Further, many ethical questions will likely arise as ABA providers begin thinking about and assessing their clinical and business operations through a value-based care lens. Though value-based care will likely roll out slowly and incrementally over many years, ABA providers interested in participating or leading these conversations will likely benefit from focusing collaborative efforts around: normalizing data sharing and self-analysis; defining and developing quality and cost measures; identifying patient risk variables; addressing challenges at the intersection of public health ethics and clinical ethics; and addressing challenges at the intersection of AI ethics and clinical ethics. Most probably agree that optimizing patient outcomes is the goal of ABA services. However, doing it in an objective, measurable, and consistent manner that can be validated by third-parties will require overcoming significant challenges.
Using UTAUT2 to Examine Mobile Payment Usage in Kirtipur
Authors: Maharjan Bikram , KC Sudarshan
Published: December 2023

Mobile payment has been a game changer innovation in the financial payment system in the world that has changed the way of life of people. It encourages people to buy and sell goods and services from anywhere using their smart phones. The purpose of the study is to explore the relationship between performance expectancy, effort expectancy, social influence, facilitating condition, hedonic motivation, price value and habit on behavioral intention of people to use mobile payment by using UTAUT2 (Unified Theory of Acceptance and Use of Technology. Quantitative research was carried out for the purpose. Data was collected from 79 valid questionnaires received from respondents came across in Kirtipur area. The data was processed using SPSS 25th version. The findings revealed that there is a significant and positive influence of performance expectancy, effort expectancy, social influence, facilitating condition, hedonic motivation, price value and habit on behavioral intention of people who are using smart phone.
Binocular Function in Adults Before and after Strabismus Surgery
Authors: Šneidrová Jarmila , Novotný Tomáš
Published: December 2023

Purpose: To evaluate the state of binocular vision, the amount and direction of the ocular deviation before and after strabismus surgery in adult patients and to monitor the occurrence of postoperative complications.

Methods: The retrospective study of 58 adult patients with selected types of strabismus who were surgically treated in the Eye Department of the Tomas Bata Regional Hospital in Zlín. We evaluated the amount and the degree of the primary ocular deviation and the binocular alignment before and after surgery, as well as the state of binocular vision after surgery and the occurrence of postoperative complications.

Results: The average deviation in convergent strabismus before surgery was +23.46 degrees, after surgery +6.6 degrees, in divergent strabismus it was -21.5 degrees, after surgery -1.48 degrees, for vertical strabismus before surgery +12.5 degrees and +3.75 degrees after surgery and in paralytic strabismus +20 degrees before surgery and +3 degrees postoperatively. Preoperatively there was effectively no binocular vision in up to 63.9% of patients, superposition occurred in 31%, fusion in 5.1%. No patient had stereopsis before surgery. After surgery, superposition was present in 39.7%, fusion in 31% and stereopsis in 6.9% of patients. Only 22.4% of patients experienced no binocular vision after surgery. Of the selected 21 patients out of 58 with an observation period of at least 3 years, we observed an improvement or development of binocular vision functions after surgery in 12 patients and no improvement of binocular vision functions in 9 patients. In the first group, 58.3% had a stable deviation throughout the follow-up period. While in the second group the deviation was stable in only 33.3%. We can assume that the improvement in binocular vision function after strabismus surgery, leads to a greater longer-term stability of postoperative deviations.

Conclusion: Strabismus surgery in adult patients is an effective and safe method, which is not only a cosmetic procedure used to adjust the position of the eyes, but also enables us to induce or improve the state of binocular vision functions.
Settler Urbanization and Indigenous Resistance: Uncovering an Ongoing Palimpsest in Montreal’s Cabot Square
Authors: Marceau Stéphane Guimont , Buckell Jennifer , Gagné Marie-Ève Drouin , Léonard Naomie , Vincent Raphaëlle Ainsley
Published: December 2023

This article proposes to study a public square in Montreal, Québec, Canada, to illustrate how different processes of colonization, marginalization, and resistance take place in the city. The study of Cabot Square demonstrates the layers of Indigenous displacement and reappropriation that form the palimpsest inscribed in urban spaces. The authors shed new light on the contemporary context by studying it through the scale of a place and reinserting it in the context of settler colonialism in which social, political, and economic relations in Canada are deeply interwoven. Cities play a major role in colonial dynamics and in the processes of marginalization in a colonial division of space that places certain populations outside the spaces of power. Cabot Square is inscribed in these dynamics, but it is also a site of reappropriation, since services for people experiencing houselessness, cultural activities, and social economy projects intersect there, placing this public place at the heart of daily encounters. The study of Cabot Square as a place of diverse and often contradictory relationships, stories, and practices of urban place-making and Indigenous place-keeping reveals layers of colonialism and Indigenous resistance that overlap through history and interact to form the current cityscape in the Square and beyond. With this article, the authors aim to acknowledge the tensions and complexities of place-making within a settler-colonial context where Indigenous histories and meanings of places not only have been erased by colonial power but also kept alive as much as possible by Indigenous communities through place-keeping.
Comparative analysis of the risk assessment of fatal and non-fatal cardiovascular events using SCORE/SCORE2 in patients at the outpatient stage
Authors:   Voronezh State Medical University named after N.N. Burdenko, Lagutina S.N. ,   Voronezh, Russian Federation, Pashkova A.A. ,   Voronezh State Medical University named after N.N. Burdenko; Voronezh, Russian Federation, Dobrynina I.S. ,   Voronezh State Medical University named after N.N. Burdenko; Voronezh, Russian Federation, Esina E.Yu. ,   Voronezh State Medical University named after N.N. Burdenko; Voronezh, Russian Federation, Shevtsova V.I. ,   Voronezh State Medical University named after N.N. Burdenko; Voronezh, Russian Federation, Shevtsov A.N. ,   Voronezh State Medical University named after N.N. Burdenko; Voronezh, Russian Federation
Published: December 2023

The purpose of the study: analysis of the risk assessment of cardiovascular events using the SCORE/SCORE2 scales in patients at the outpatient stage. Design: comparative study. Materials and methods. A retrospective analysis of 140 electronic medical records of outpatients was conducted. The criteria for inclusion in the study were: the age of respondents over 40 years old, the absence of concomitant cardiovascular diseases, type 2 diabetes. The following indicators were analyzed in patients: the level of total cholesterol, blood pressure, on the basis of which the risk of cardiovascular events was calculated using the SCORE and SCORE2 scales, for older people — SCORE2-OP. A comparative assessment of the results was carried out. Results. Statistically significant differences were identified between the values obtained when assessing cardiovascular events using SCORE (Me men = 9.5 points, Me women = 3 points, p < 0.001) and SCORE2 (Me men = 22 points, Me women = 18 points, p = 0.049) in the age group from 50 to 70 years. It was found that most patients have a moderate risk of developing cardiovascular complications according to the SCORE scale, and in accordance with the updated SCORE2 algorithm - a very high risk. Conclusion. A comparison of the 10-year risk of cardiovascular complications calculated using SCORE and the new SCORE2 algorithm revealed significant differences between them. Patients are at very high risk of complications (according to the SCORE2 questionnaire), which absolutely increases the risk of complications. Significantly higher values for SCORE2, SCORE2-OP can be associated with indicators such as blood pressure levels and lipid profile indicators. Keywords: screening, cardiovascular pathology, SCORE, SCORE2, outpatient stage
PERANAN KOMUNIKASI PEMASARAN TERPADU DALAM MEMBANGUN KESADARAN MEREK “LOTOTO” PT. GLOBAL TRI SOLUSINDO
Authors: Ramadhani Alifia , Abdurahman Ade Irfan , Khairani Aulian
Published: December 2023

Penelitian ini bertujuan untuk mengetahui strategi lototo dalam membangun kesadaran merek dengan meninjau peranan teori komunikasi pemasaran terpadu. Diantara kompetitor lainnya, lototo merupakan merek baru yang menjual produk safety lockout tagout, untuk membangun kesadaran merek diperlukan strategi komunikasi pemasaran yang efektif dengan memadukan unsur dari komunikasi pemasaran terpadu Kotler dan Amstrong (2001:600). Penelitian ini menggunakan pendekatan kualitatif deskriptif, dengan teknik pengumpulan data secara observasi, wawancara, dan dokumentasi. Wawancara dilakukan dengan sejumlah informan internal lototo, dan informan eksternal yang merupakan konsumen lototo. Hasil dari penelitian ini mengungkapkan lototo menggunakan unsur komunikasi pemasaran terpadu diantaranya periklanan, sales, promosi penjualan, pemasaran interaktif, dan pemasaran langsung. Kesimpulan dari penelitian ini menunjukan lototo berhasil mengimplementasi peranan teori komunikasi pemasaran terpadu dengan baik yang memadukan unsur komunikasi pemasaran Kotler dan Amstrong (2001:600) dalam membangun kesadaran merek. Kata Kunci: Komunikasi Pemasaran Terpadu; Unsur Komunikasi Pemasaran; Kesadaran Merek.
Doctor Tirta’s Branding As An Influencer In The Telemedicine Program
Authors: Irawan Irawan , Azkiyah Lulu Nurul , Utomo Ardian Setio , Warhamni Dewi
Published: December 2023

New media presents social media as a medium for interacting, collaborating, sharing, communicating, and forming social bonds with other users. During the COVID-19 pandemic, influencers used new media to socialize Covid-19 prevention and build personal branding. Dr. Tirta is an influencer in building personal branding with the telemedicine program he created. Telemedicine has received a lot of positive responses from the public. This research aims to determine the personal branding of Dr. Tirta as an influencer in the telemedicine program. The theory used in this research is Montoya's eight Personal Branding theories. This research uses a qualitative method with a descriptive approach. In collecting data using observation techniques, in-depth interviews with telemedicine patients, Dr. Tirta, and documentation. The research results show that Dr. Tirta has described eight personal branding concepts from Montoya. The specialty of Dr. Tirta is different from the concept of personal branding in general. Dr. Tirta does not focus on one unique skill. He has two skills, namely, in business and health. Apart from that, Dr. Tirta is an eccentric appearance characterizes, and his way of speaking seems blunt. Its consistency and determination in educating the public regarding health on social media with attractive packaging also give a positive impression.
Ишемическая болезнь сердца: от традиционных хирургических и консервативных подходов к клеточной кардиомиопластике и лазерной реваскуляризации
Authors: Zalessky V. M. , Nudchenko O. O.
Published: December 2023

Ішемія міокарда і серцева дисфункція лежать в основі ішемічної хвороби серця. Клітинна терапія і лазерна реваскуляризація мають значні можливості для вирішення проблем репарації пошкоджень серця і судин, що підтверджено численними адекватними доклінічними дослідженнями. У статті наведено аналіз даних про трансплантацію мезенхімальних стовбурових клітин і лазерну реваскуляризацію для регенерації міокарда.
Клінічні особливості екстрапірамідних порушень, пов’язаних з феноменом діашізу, у хворих після ішемічного інсульту
Authors: Ovodyuk N. M.
Published: December 2023

вольових порушень після ішемічного інсульту, пов’язані з феноменом метаболічного діашізу. Порівнювали показники досліджень хворих через 1 міс після гострої події в двох групах хворих (основна – хворі з екстрапірамідними порушеннями, контрольна – без них). Рухові порушення оцінювали за шкалою UPDRS (3-тя частина), когнітивні та емоційно-вольові – за шкалами MMSE та PHQ-9. Виявлено екстрапірамідний дефіцит, пов’язаний з феноменом діашізу, що ускладнювало легкий руховий постінсультний дефіцит та загальний стан даних хворих.
Аспекти терапії остменопаузального остеопорозу в загальнолікарській практиці (клінічний випадок)
Authors: Zhdan V. M. , Kitura O. E. , Kitura E. M. , Babanina M. Yu. , Tkachenko M. V.
Published: December 2023

Описано випадок постменопаузального остеопорозу з компресійним переломом хребта у пацієнтки з ранньою хірургічною менопаузою. Розглянуто основні фактории ризику остеопорозу, клінічні прояви, методи діагностики, основні заходи профілактики і фармакологічної корекції, зокрема бісфосфонатами.
Оценка клинико-патогенетической эффективности комбинации реамберина и циклоферона у больных острым тонзиллитом тяжёлого течения
Authors: Frolov V. М. , Тereshin V. O. , Sotska Ya. A. , Peresadin M. O. , Кruglova O. V.
Published: December 2023

Вивчено ефективність застосування комбінації реамберину та циклоферону в хворих на гострий тонзиліт тяжкого перебігу. Встановлено, що застосування комбінації реамберину та циклоферону в комплексі лікування даних хворих забезпечує прискорення нормалізації загального стану та покращанню самопочуття хворих, усуненню як загальнотоксичного синдрому, так і локальних запальних проявів у ротовій частині глотці, а також нормалізації вивчених біохімічних та імунологічних показників. Застосування реамберину та циклоферону сприяє зниженню рівня "середніх молекул" та малонового діальдегіду до верхньої межі норми, що свідчить про усунення синдрому ендогенної "метаболічної" інтоксикації, а також сприяє нормалізації показників фагоцитарної активності моноцитів. Це вказує на позитивну дію даної комбінації на функціональний стан макрофагальної фагоцитуючої системи.