bluuebunny/crossref_metadata_2025 huggingface dataset:
Process analysis of solar steam reforming of methane for producing low-carbon hydrogen
Authors: Shagdar Enkhbayar , Lougou Bachirou Guene , Shuai Yong , Ganbold Enkhjin , Chinonso Ogugua Paul , Tan Heping
Published: March 2020

Integrating solar thermal energy into conventional SRM technology is a promising approach for low-carbon hydrogen production based on fossil fuel in near and midterm.
Visible light-mediated photocatalytic oxidative cleavage of activated alkynes via hydroamination: a direct approach to oxamates
Authors: Katta Narenderreddy , Ojha Mamata , Murugan Arumugavel , Arepally Sagar , Sharada Duddu S.
Published: March 2020

The direct oxidative cleavage of activated alkynes via hydroamination has been described using organic photocatalyst under visible-light irradiation at room temperature.
Biosynthetic access to the rare antiarose sugar via an unusual reductase-epimerase
Authors: Yan Yijun , Yang Jing , Wang Li , Xu Dongdong , Yu Zhiyin , Guo Xiaowei , Horsman Geoff P. , Lin Shuangjun , Tao Meifeng , Huang Sheng-Xiong
Published: March 2020

Rubrolones, isarubrolones, and rubterolones are recently isolated glycosylated tropolonids with notable biological activity.
Synthesis, conformational analysis and in vivo assays of an anti-cancer vaccine that features an unnatural antigen based on an sp2-iminosugar fragment
Authors: Bermejo Iris A. , Navo Claudio D. , Castro-López Jorge , Guerreiro Ana , Jiménez-Moreno Ester , Sánchez Fernández Elena M. , García-Martín Fayna , Hinou Hiroshi , Nishimura Shin-Ichiro , García Fernández José M. , Mellet Carmen Ortiz , Avenoza Alberto , Busto Jesús H. , Bernardes Gonçalo J. L. , Hurtado-Guerrero Ramón , Peregrina Jesús M. , Corzana Francisco
Published: March 2020

An anti-cancer vaccine based on an unnatural antigen with an sp2-iminosugar fragment.
Dynamic behavior analysis of ion transport through a bilayer lipid membrane by an electrochemical method combined with fluorometry
Authors: Omatsu Terumasa , Hori Kisho , Naka Yasuhiro , Shimazaki Megumi , Sakai Kazushige , Murakami Koji , Maeda Kohji , Fukuyama Mao , Yoshida Yumi
Published: March 2020

The ion transport through a bilayer lipid membrane was analyzed by an electrochemical method combined with fluorometry. The distribution of a cation and an anion predominantly determines membrane conductivity.
One-incubation one-hour multiplex ELISA enabled by aqueous two-phase systems
Authors: Tongdee Mintra , Yamanishi Cameron , Maeda Midori , Kojima Taisuke , Dishinger John , Chantiwas Rattikan , Takayama Shuichi
Published: March 2020

This work presents one-incubation one-hour multiplex ELISA enabled by aqueous two-phase systems for five-plex cytokine detection in human ThP-1 macrophages.
Transition metal dichalcogenide/multi-walled carbon nanotube-based fibers as flexible electrodes for electrocatalytic hydrogen evolution
Authors: Chen Bo , Sun Gengzhi , Wang Jie , Liu Guigao , Tan Chaoliang , Chen Ye , Cheng Hongfei , Chen Junze , Ma Qinglang , Huang Ling , Chen Peng , Zhang Hua
Published: March 2020

Fabrication of binder-free, flexible, and weavable transition metal dichalcogenide nanosheet-based hybrid fibers for electrocatalytic hydrogen evolution.
Are ionic liquids and liquid coordination complexes really different? – Synthesis, characterization, and catalytic activity of AlCl3/base catalysts
Authors: Kore Rajkumar , Kelley Steven P. , Sawant Anand D. , Mishra Manish Kumar , Rogers Robin D.
Published: March 2020

Unique Lewis acid/base liquid coordination catalysts were compared to the known super acidic ionic liquid chloroaluminates and found to have higher catalytic activity in the alkylation of benzene.
Nitroprusside as a promising building block to assemble an organic–inorganic hybrid for thermo-responsive switching materials
Authors: Qiu Rong-Guan , Chen Xiao-Xian , Huang Rui-Kang , Zhou Dong-Dong , Xu Wei-Jian , Zhang Wei-Xiong , Chen Xiao-Ming
Published: March 2020

A new nitroprusside-based hybrid (Me2NH2)[KFe(CN)5(NO)] exhibits thermo-responsive switching behaviours on uniaxial expansivity and SHG signal owing to flexible host–guest hydrogen bonds and the synchronously deformable inorganic framework.
Melting point–solubility–structure correlations in chiral and racemic model cocrystals
Authors: Kilinkissa Ornella E. Y. , Govender Krishna K. , Báthori Nikoletta B.
Published: March 2020

Comparison of chiral and racemic binary cocrystals showed that the chiral building block limits the formation of certain intermolecular interactions, decreases the packing efficiency, lowers the melting point and increases aqueous solubility.
Mechanochemistry: an efficient and versatile toolbox for synthesis, transformation, and functionalization of porous metal–organic frameworks
Authors: Stolar Tomislav , Užarević Krunoslav
Published: March 2020

Multiple ways in which the synergy of mechanochemistry and MOFs advances the field of materials chemistry are presented here.
The wetting behavior of aqueous imidazolium based ionic liquids: a molecular dynamics study
Authors: Bhattacharjee Sanchari , Khan Sandip
Published: March 2020

Aqueous hydrophilic and hydrophobic ionic liquid droplet on graphite sheet.
Characterization of the alkali metal oxalates (MC2O4−) and their formation by CO2 reduction via the alkali metal carbonites (MCO2−)
Authors: Jestilä Joakim S. , Denton Joanna K. , Perez Evan H. , Khuu Thien , Aprà Edoardo , Xantheas Sotiris S. , Johnson Mark A. , Uggerud Einar
Published: March 2020

The reduction of carbon dioxide to oxalate has been studied by experimental Collisionally Induced Dissociation (CID) and vibrational characterization of the alkali metal oxalates, supplemented by theoretical electronic structure calculations.
Ultrahigh yield synthesis of mesoporous carbon nanoparticles as a superior lubricant additive for polyethylene glycol
Authors: Mou Zihao , Wang Baogang , Huang Zhiyu , Lu Hongsheng
Published: March 2020

Mesoporous carbon nanoparticles (MCNPs) with an average particle size of 27.3 nm and a pore size of 3–5 nm were facilely synthesized in ultrahigh yield (91.7 wt%) and used as a high-performance lubricant additive for polyethylene glycol (PEG200).
Interactions of emerging contaminants with model colloidal microplastics, C60 fullerene, and natural organic matter – effect of surface functional group and adsorbate properties
Authors: Williams Tyler , Walsh Clare , Murray Keith , Subir Mahamud
Published: March 2020

Molecular properties of emerging contaminants (ECs) and interfacial compositions of colloidal matter dictate the extent of EC–particulate matter surface interaction.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Authors: Naddeo Vincenzo , Liu Haizhou
Published: March 2020

Vincenzo Naddeo and Haizhou Liu present an ‘Editorial Perspective’ on coronavirus in wastewater and discuss the water research needs to combat viral outbreaks.
Properties and activity of Zn–Ta-TUD-1 in the Lebedev process
Authors: Pomalaza Guillaume , Simon Pardis , Addad Ahmed , Capron Mickaël , Dumeignil Franck
Published: March 2020

A zinc and tantalum-containing mesoporous silica catalyst highly active and selective in the Lebedev process has been prepared using the one-pot TUD-1 methodology. Characterization established a correlation between acidity and butadiene formation.
Non-ionic hydrophobic eutectics – versatile solvents for tailored metal separation and valorisation
Authors: Schaeffer Nicolas , Conceição João H. F. , Martins Mónia A. R. , Neves Márcia C. , Pérez-Sánchez Germán , Gomes José R. B. , Papaiconomou Nicolas , Coutinho João A. P.
Published: March 2020

The potential of HESs as environmentally benign and tunable media for the solvent extraction of metal ions is presented.
A new integrated method of magnetic separation of isoquinoline alkaloids from Coptis chinensis based on their magnetized derivatives and key physical properties
Authors: Nie Lirong , Feng Xueting , Song Hang , Li Zicheng , Yao Shun
Published: March 2020

For the first time, a new magnetic separation strategy for the separation of alkaloids from Coptis chinensis was developed in this study.
Oxidative ability of organic iodine(iii) reagents: a theoretical assessment
Authors: Radzhabov Maxim R. , Sheremetev Aleksei B. , Pivina Tatyana S.
Published: March 2020

Computational prediction of the oxidative ability of hypervalent iodine reagents was performed based on redox potentials, calculated at the B3LYP/6-311+G(d,p) level of theory with the SDD ECP46MDF pseudopotential for the iodine atom.
Thermal and light irradiation effects on the electrocatalytic performance of hemoglobin modified Co3O4-g-C3N4 nanomaterials for the oxygen evolution reaction
Authors: Leal-Rodríguez Carlos , Rodríguez-Padrón Daily , Alothman Zeid A. , Cano Manuel , Giner-Casares Juan J. , Muñoz-Batista Mario J. , Osman Sameh M. , Luque Rafael
Published: March 2020

A mechanochemically synthesized ternary bioconjugate nanomaterial exhibited interesting electrocatalytic behavior for OER.
Coupling amorphous cobalt hydroxide nanoflakes on Sr2Fe1.5Mo0.5O5+δ perovskite nanofibers to induce bifunctionality for water splitting
Authors: He Beibei , Tan Kun , Gong Yansheng , Wang Rui , Wang Huanwen , Zhao Ling
Published: March 2020

Herein, a facile and efficient surface modification approach to boosting the bifunctionally of perovskites for overall water splitting is provided, and the construction of amorphous Co(OH)2 on Sr2Fe1.5Mo0.5O5+δ surface is conducted.
Correction: A robust Mn@FeNi-S/graphene oxide nanocomposite as a high-efficiency catalyst for the non-enzymatic electrochemical detection of hydrogen peroxide
Authors: Manavalan Shaktivel , Ganesamurthi Jaysiva , Chen Shen-Ming , Veerakumar Pitchaimani , Murugan Keerthi
Published: March 2020

Correction for ‘A robust Mn@FeNi-S/graphene oxide nanocomposite as a high-efficiency catalyst for the non-enzymatic electrochemical detection of hydrogen peroxide’ by Shaktivel Manavalan et al., Nanoscale, 2020, 12, 5961–5972.
Catalyst and solvent switched divergent C–H functionalization: oxidative annulation of N-aryl substituted quinazolin-4-amine with alkynes
Authors: Meesa Siddi Ramulu , Naikawadi Praveen Kumar , Gugulothu Kishan , Shiva Kumar K.
Published: March 2020

Catalyst and solvent controlled ortho/peri site-selective oxidative annulation of C–H bonds of N-aryl substituted quinazolin-4-amines with internal alkynes.
Tin(ii) 2-ethylhexanoate catalysed methanolysis of end-of-life poly(lactide)
Authors: Hofmann Melanie , Alberti Christoph , Scheliga Felix , Meißner Roderich R. R. , Enthaler Stephan
Published: March 2020

The depolymerisation of end-of-life poly(lactide) (PLA) goods was studied as part of the chemical recycling of PLA.
Facile assembly of a graphitic carbon nitride film at an air/water interface for photoelectrochemical NADH regeneration
Authors: Jia Changchao , Hu Wenjuan , Zhang Yuanyuan , Teng Chao , Chen Zupeng , Liu Jian
Published: March 2020

A graphitic carbon nitride film electrode could be assembled at an air/water interface from nanosheets which exhibits improved photoelectrochemical coenzyme regeneration by further coupling with graphene during the interfacial self-assembly.
Ultrathin permselective membranes: the latent way for efficient gas separation
Authors: Castro-Muñoz Roberto , Agrawal Kumar Varoon , Coronas Joaquín
Published: March 2020

This review focuses on the application of ultrathin membranes for gas separation, describing the membrane preparation protocols applied. This includes atomic layer deposition, in situ crystal formation, interfacial polymerization and Langmuir–Blodgett technique.
Retraction: Honeycomb-like Co–B amorphous alloy catalysts assembled by a solution plasma process show enhanced catalytic hydrolysis activity for hydrogen generation
Authors: Tong Dong Ge
Published: March 2020

Retraction of ‘Honeycomb-like Co–B amorphous alloy catalysts assembled by a solution plasma process show enhanced catalytic hydrolysis activity for hydrogen generation’ by Dong Ge Tong et al., RSC Adv., 2012, 2, 2369–2376.
Assessing the impact of deviations in optimized multistep flow synthesis on the scale-up
Authors: Sharma M. K. , Raval J. , Ahn Gwang-Noh , Kim Dong-Pyo , Kulkarni A. A.
Published: March 2020

This manuscript highlights the unavoidable connection between manual and self-optimized flow synthesis protocols for multistep flow synthesis and its scale-up.
Shape-directed self-assembly of nanodumbbells into superstructure polymorphs
Authors: Liu Yulian , Deng Kerong , Yang Jun , Wu Xiaotong , Fan Xiaokun , Tang Min , Quan Zewei
Published: March 2020

Nanodumbbells were assembled into superstructures with three orientations, and distinct roles of individual subunits of nanodumbbells in the assembly are uncovered.
Asymmetric gel polymer electrolyte with high lithium ion conductivity for dendrite-free lithium metal batteries
Authors: Li Linge , Wang Mingchao , Wang Jian , Ye Fangmin , Wang Shaofei , Xu Yanan , Liu Jingyu , Xu Guoguang , Zhang Yue , Zhang Yongyi , Yan Cheng , Medhekar Nikhil V. , Liu Meinan , Zhang Yuegang
Published: March 2020

An asymmetric gel polymer electrolyte is designed for regulating ions and suppressing Li dendrite growth in high-performance Li metal batteries.
Retraction: Mesoporous multiwalled carbon nanotubes as supports for monodispersed iron–boron catalysts: improved hydrogen generation from hydrous hydrazine decomposition
Authors: Tong Dong Ge
Published: March 2020

Retraction of ‘Mesoporous multiwalled carbon nanotubes as supports for monodispersed iron–boron catalysts: improved hydrogen generation from hydrous hydrazine decomposition’ by Dong Ge Tong et al., J. Mater. Chem. A, 2013, 1, 358–366.
How do cells sense DNA lesions?
Authors: Colombo Chiara Vittoria , Gnugnoli Marco , Gobbini Elisa , Longhese Maria Pia
Published: March 2020

DNA is exposed to both endogenous and exogenous DNA damaging agents that chemically modify it. To counteract the deleterious effects exerted by DNA lesions, eukaryotic cells have evolved a network of cellular pathways, termed DNA damage response (DDR). The DDR comprises both mechanisms devoted to repair DNA lesions and signal transduction pathways that sense DNA damage and transduce this information to specific cellular targets. These targets, in turn, impact a wide range of cellular processes including DNA replication, DNA repair and cell cycle transitions. The importance of the DDR is highlighted by the fact that DDR inactivation is commonly found in cancer and causes many different human diseases. The protein kinases ATM and ATR, as well as their budding yeast orthologs Tel1 and Mec1, act as master regulators of the DDR. The initiating events in the DDR entail both DNA lesion recognition and assembly of protein complexes at the damaged DNA sites. Here, we review what is known about the early steps of the DDR.
Cyclin D1 promotes secretion of pro-oncogenic immuno-miRNAs and piRNAs
Authors: Lü Jinhui , Zhao Qian , Ding Xin , Guo Yuefan , Li Yuan , Xu Zhen , Li Shujun , Wang Zhongrui , Shen Lei , Chen Huang-wen , Yu Zuoren , Pestell Richard G.
Published: March 2020

The molecular mechanisms governing the secretion of the non-coding genome are poorly understood. We show herein that cyclin D1, the regulatory subunit of the cyclin-dependent kinase that drives cell-cycle progression, governs the secretion and relative proportion of secreted non-coding RNA subtypes (miRNA, rRNA, tRNA, CDBox, scRNA, HAcaBox. scaRNA, piRNA) in human breast cancer. Cyclin D1 induced the secretion of miRNA governing the tumor immune response and oncogenic miRNAs. miR-21 and miR-93, which bind Toll-Like Receptor 8 to trigger a pro-metastatic inflammatory response, represented >85% of the cyclin D1-induced secreted miRNA transcripts. Furthermore, cyclin D1 regulated secretion of the P-element Induced WImpy testis (PIWI)-interacting RNAs (piRNAs) including piR-016658 and piR-016975 that governed stem cell expansion, and increased the abundance of the PIWI member of the Argonaute family, piwil2 in ERα positive breast cancer. The cyclin D1-mediated secretion of pro-tumorigenic immuno-miRs and piRNAs may contribute to tumor initiation and progression.
miR-210 transferred by lung cancer cell-derived exosomes may act as proangiogenic factor in cancer-associated fibroblasts by modulating JAK2/STAT3 pathway
Authors: Fan Junqiang , Xu Guanxin , Chang Zhibo , Zhu Ling , Yao Jie
Published: March 2020

It has been generally believed that cancer-associated fibroblasts (CAFs) have the ability to increase the process of tumor angiogenesis. However, the potential mechanisms by which cancer-derived exosomes in lung cancer (LC) remains to be investigated. LC-derived exosomes were administrated to NIH/3T3 cells. A variety of experiments were conducted to investigate the proangiogenic factors of CAFs, including Western blot, RT-PCR, colony formation assay, tube formation assay, Matrigel plug assay et al. In addition, the impact of JAK2/STAT3 signaling pathway were also explored. The role of hsa-miR-210 was identified with microarray profiling and validated in vitro and in vivo assays. The target of miR-210 was screened by RNA pull down, RNA-sequencing and then verified. It was shown that LC-derived exosomes could induce cell reprogramming, thus promoting the fibroblasts transferring into CAFs. In addition, the exosomes with overexpressed miR-210 could increase the level of angiogenesis and vice versa, which suggested the miR-210 secreted by the LC-derived exosomes may initiate the CAF proangiogenic switch. According to our analysis, the miR-210 had the ability of elevating the expression of some proangiogenic factors such as MMP9, FGF2 and vascular endothelial growth factor (VEGF) a (VEGFa) by activating the JAK2/STAT3 signaling pathway, ten-eleven translocation 2 (TET2) was identified as the target of miR-210 in CAFs which has been involved in proangiogenic switch. miR-210 was overexpressed in serum exosomes of untreated non-small cell LC (NSCLC) patients. We concluded that the promotion effect of exosomal miR-210 on proangiogenic switch of CAFs may be explained by the modulation of JAK2/STAT3 signaling pathway and TET2 in recipient fibroblasts.
Short-chain fatty acid, acylation and cardiovascular diseases
Authors: Chen Xiao-Feng , Chen Xiangqi , Tang Xiaoqiang
Published: March 2020

Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide. Metabolic dysfunction is a fundamental core mechanism underlying CVDs. Previous studies generally focused on the roles of long-chain fatty acids (LCFAs) in CVDs. However, a growing body of study has implied that short-chain fatty acids (SCFAs: namely propionate, malonate, butyrate, 2-hydroxyisobutyrate (2-HIBA), β-hydroxybutyrate, crotonate, succinate, and glutarate) and their cognate acylations (propionylation, malonylation, butyrylation, 2-hydroxyisobutyrylation, β-hydroxybutyrylation, crotonylation, succinylation, and glutarylation) participate in CVDs. Here, we attempt to provide an overview landscape of the metabolic pattern of SCFAs in CVDs. Especially, we would focus on the SCFAs and newly identified acylations and their roles in CVDs, including atherosclerosis, hypertension, and heart failure.
Kalman rank criterion for the controllability of fractional impulse controlled systems
Authors: Cai Rui‐Yang , Zhou Hua‐Cheng , Kou Chun‐Hai
Published: March 2020

This study aims to address the impulsive controllability of linear fractional impulse controlled systems. The authors establish the Kalman rank criterion to guarantee the impulsive controllability of the considered system. They also present the minimum number of impulsive controls for a realisation of such controllability. An example is finally presented to demonstrate the effectiveness of the authors' results.
VV 655 and NGC 4418: Implications of an interaction for the evolution of a LIRG
Authors: Boettcher Erin , Gallagher III John S. , Ohyama Youichi , Varenius Eskil , Aalto Susanne , Falstad Niklas , König Sabine , Sakamoto Kazushi , Yoast-Hull Tova M.
Published: March 2020

Context. VV 655, a dwarf irregular galaxy with HI tidal debris, is a companion to the lenticular luminous infrared galaxy (LIRG) NGC 4418. NGC 4418 stands out among nearby LIRGs due to its dense central concentration of molecular gas and the dusty, bi-polar structures along its minor axis suggestive of a wind driven by a central starburst and possible nuclear activity.

Aims. We seek to understand the consequences of the ongoing minor interaction between VV 655 and NGC 4418 for the evolution of the LIRG. Specifically, we consider the origin of the gas supply responsible for the unusual nuclear properties of NGC 4418.

Methods. We investigate the structural, kinematic, and chemical properties of VV 655 and NGC 4418 by analyzing archival imaging data and optical spectroscopic observations from the SDSS-III and new spectra from SALT-RSS. We characterize their gas-phase metal abundances and spatially resolved, ionized gas kinematics to better understand whether gas transfer between VV 655 and NGC 4418 resulted in the highly obscured nucleus of the LIRG.

Results. The gas-phase metallicity in NGC 4418 significantly exceeds that in VV 655. No kinematic disturbances in the ionized gas are observed along the minor axis of NGC 4418, but we see evidence for ionized gas outflows from VV 655 that may increase the cross-section for gas stripping in grazing collisions. A faint, asymmetric outer arm is detected in NGC 4418 of the type normally associated with galaxy-galaxy interactions.

Conclusions. The simplest model suggests that the minor interaction between VV 655 and NGC 4418 produced the unusual nuclear properties of the LIRG via tidal torquing of the interstellar medium of NGC 4418 rather than through a significant gas transfer event. In addition to inducing a central concentration of gas in NGC 4418, this interaction also produced an enhanced star formation rate and an outer tidal arm in the LIRG. The VV 655-NGC 4418 system offers an example of the potential for minor collisions to alter the evolutionary pathways of giant galaxies.
Core and crust contributions in overshooting glitches: the Vela pulsar 2016 glitch
Authors: Pizzochero P. M. , Montoli A. , Antonelli M.
Published: March 2020

During the spin-up phase of a large pulsar glitch – a sudden decrease of the rotational period of a neutron star – the angular velocity of the star may overshoot, namely reach values greater than that observed for the new post-glitch equilibrium. These transient phenomena are expected on the basis of theoretical models for pulsar internal dynamics, and their observation has the potential to provide an important diagnostic for glitch modelling. In this article, we present a simple criterion to assess the presence of an overshoot, based on the minimal analytical model that is able to reproduce an overshooting spin-up. We employed it to fit the data of the 2016 glitch of the Vela pulsar, obtaining estimates of the fractional moments of inertia of the internal superfluid components involved in the glitch, of the rise and decay timescales of the overshoot, and of the mutual friction parameters between the superfluid components and the normal one. We studied the cases with and without strong entrainment in the crust: in the former, we found an indication of a large inner core strongly coupled to the observable component, and of a reservoir of angular momentum extending into the core to densities below nuclear saturation; while in the latter, a large reservoir extending above nuclear saturation and a standard normal component without inner core were found.
Characterization of the June epsilon Ophiuchids meteoroid stream and the comet 300P/Catalina
Authors: Matlovič Pavol , Kornoš Leonard , Kováčová Martina , Tóth Juraj , Licandro Javier
Published: March 2020

Aims. Prior to 2019, the June epsilon Ophiuchids (JEO) were known as a minor unconfirmed meteor shower with activity that was considered typically moderate for bright fireballs. An unexpected bout of enhanced activity was observed in June 2019, which even raised the possibility that it was linked to the impact of the small asteroid 2019 MO near Puerto Rico. Early reports also point out the similarity of the shower to the orbit of the comet 300P/Catalina. We aim to analyze the orbits, emission spectra, and material strengths of JEO meteoroids to provide a characterization of this stream, identify its parent object, and evaluate its link to the impacting asteroid 2019 MO.

Methods. Our analysis is based on a sample of 22 JEO meteor orbits and four emission spectra observed by the AMOS network at the Canary Islands and in Chile. The meteoroid composition was studied by spectral classification based on relative intensity ratios of Na, Mg, and Fe. Heliocentric orbits, trajectory parameters, and material strengths were determined for each meteor and the mean orbit and radiant of the stream were calculated. The link to potential parent objects was evaluated using a combination of orbital-similarity D-criteria and backwards integration of the orbit of comet 300P and the JEO stream.

Results. We confirm the reports of an unexpected swarm of meteoroids originating in the JEO stream. JEO meteoroids have low material strengths characteristic for fragile cometary bodies, and they exhibit signs of a porous structure. The emission spectra reveal slightly increased iron content compared to all other measured cometary streams, but they are generally consistent with a primitive chondritic composition. Further dynamical analysis suggests that the JEO stream is likely to originate from comet 300P/Catalina and that it was formed within the last 1000 yr. Over longer timescales, the meteoroids in the stream move to chaotic orbits due to the turbulent orbital evolution of the comet. Our results also suggest that the impact of the small asteroid 2019 MO on June 22 was not connected to the JEO activity.
Le temps du traumatisme. Reconstruire l’espace de la transmission
Authors: Krischek Chantal
Published: March 2020

En faisant taire l’histoire familiale, le traumatisme porte atteinte à ce qui fait la spécificité de chaque famille : sa capacité à transmettre. La transmission ne se déroule plus dans ce mouvement incessant entre le récit et son questionnement mais devient un système purement répétitif au sein duquel les croyances évolutives se transforment en dogmes disant le « tout » de l’individu.

Dans ce contexte, l’auteure propose une lecture de différents symptômes au regard du traumatisme familial. Elle décrit, au travers d’une élaboration conceptuelle illustrée par des cas cliniques, son chemin thérapeutique qui est un remaillage collectif de l’histoire familiale. Il s’agit de (re)construire l’espace potentiel de la transmission comme un lieu comprenant suffisamment d’indétermination que pour faire surgir, à chaque génération, de l’inédit et de l’inattendu.

Le nouveau cadre proposé délimite un espace thérapeutique regroupant plusieurs générations. Grâce à la rencontre dans l’espace partagé et au travail des mémoires individuelles, les générations différentes font l’expérience commune de l’histoire qui les a précédées. La conversation familiale prend forme, rendant possible la construction du récit commun.
La trace anti-mnésique. Hypothèses sur le traumatisme psychique chez l’enfant
Authors: Marcelli Daniel
Published: March 2020

Exception faite du bébé et du très jeune enfant, le traumatisme psychique chez un enfant, si on veut bien prendre en considération ses modes particuliers d’expression tels que le jeu ou le dessin ne diffère pas fondamentalement dans son expression sémiologique de celui de l’adulte. Dans l’un et l’autre cas, on retrouve les mêmes termes pour décrire ce que la victime a subi au point qu’on peut en proposer un glossaire ! De même chez l’enfant comme chez l’adulte, la répétition, parfois compulsive, fait de cet événement unique quelque chose qui tend à se répéter, ce qui pose au psychiatre une énigme majeure laquelle conduisit S. Freud le premier à remanier sa théorie des pulsions. Car si parfois la trace de ce traumatisme peut, après coup, subir l’effet d’un refoulement et se transformer en symptôme, dans d’autres cas elle semble persister intangible chez l’individu quand ce n’est pas dans sa descendance ! Comment comprendre l’effet de cette trace laissée dans le fonctionnement neurocognitif sans pour autant qu’elle puisse faire l’objet d’une transformation psychique ? C’est ce qu’on observe tout particulièrement dans les traumatismes qui affectent les très jeunes enfants, à un âge où, encore dépourvus de langage, ils semblent prisonniers de cette incapacité d’élaboration. L’auteur propose de nommer celle-ci « trace anti-mnésique » car précisément le travail de la mémoire ne peut s’effectuer. Ces distinctions ne sont pas seulement académiques car elles ont un intérêt majeur dans l’orientation des soins, l’auteur opposant la lacune énigmatique sur laquelle un travail associatif peut s’effectuer, à la « trace anti-mnésique » où ce travail risque fort d’être voué à l’échec s’il n’est pas relayé par un accompagnement au plus près des perceptions sensorielles.
Die zwei Quellen des Sinns: Eine Kritik der psychiatrischen Hermeneutik in Anknüpfung an Schleiermacher
Authors: Brücher Klaus
Published: March 2020

Einleitung Die psychiatrische Hermeneutik bedenkt einzig den subjektiven Sinn und übersieht damit eine ganze Sinndimension, den von Schleiermacher so genannten „grammatischen Sinn“, der autonom – gemäß den Regeln von Sprache und Sozialität – generiert wird.

Methode Am Leitfaden von drei Postulaten in Schleiermachers Hermeneutik wird die Problemstellung entfaltet: Dass zwei Sinndimensionen – subjektiver und grammatischer Sinn – angenommen werden müssen, diese strikt voneinander zu unterscheiden sind, gleichwohl nur in ihrem „Ineinandersein“ Verstehen gewährleisten. Wo Schleiermacher im Wesentlichen auf eine philologische Deutung der grammatischen Sinndimension verwiesen war, stehen uns fast 200 Jahre später Optionen zur Verfügung, die allererst das in dieser Dimension enthaltene Potenzial auszuschöpfen erlauben.

Schlussfolgerungen Wird Sinn als ein in der Interaktion Zug um Zug sich herstellendes Produkt begriffen, verändern sich die Perspektive und mit ihr die hergebrachten Auffassungen grundlegend: Bedeutung wird dann zwischen den Interaktanden generiert, mithin nicht in ihnen, weder in ihrer Seele noch in ihrem Gehirn.

Erst eine Konzeptualisierung, die das Medium von Sprache und Sozialität in seiner Eigengesetzlichkeit zum ersten Gegenstand des Verstehens macht, kann verständlich machen, was wir im Verstehen tatsächlich verstehen: Sinn – als die Art und Weise, wie ein Subjekt sich im Medium von Sprache und Sozialität selbst reproduziert.
Infizierte Urachuszyste beim Erwachsenen, Manifestation als Urosepsis
Authors: Albarghouth Mohamad Hatem , Dober Susanne , Kramer Thomas , Hamza Amir
Published: March 2020

Im Nachfolgenden wird der Fall eines 81-jährigen Patienten dargestellt. Dieser stellte sich akut über die Notaufnahme unseres Hauses unter dem Bild einer Urosepsis bei Harnblasenkatheter-pflichtiger benigner Prostatahyperplasie vor. Im Rahmen der weiterführenden Diagnostik konnte eine infizierte Urachuszyste als ursächlicher Fokus festgestellt werden. Es erfolgte die chirurgische Therapie der infizierten Urachuszyste.
Vasorelaxant and Antihypertensive Effects of Neferine in Rats: An In Vitro and In Vivo Study
Authors: Wicha Piyawadee , Onsa-ard Amnart , Chaichompoo Waraluck , Suksamrarn Apichart , Tocharus Chainarong
Published: March 2020

The present study was performed to examine the antihypertensive effect of neferine in hypertensive rats and its relaxant mechanisms in isolated rat thoracic aorta. The antihypertensive effect was evaluated by tail-cuff methods on NG-nitro-L-arginine methyl ester (L-NAME) (40 mg/kg BW) 4-week hypertensive-induced hypertensive rats. The vasorelaxant effect and its mechanisms were studied by the organ bath technique in the thoracic aorta isolated from normotensive rats. The results indicated that the treatment of neferine (1 mg/kg and 10 mg/kg) markedly decreased the systolic blood pressure (SBP) when compared with the hypertension group (137.75 ± 10.14 mmHg and 132.23 ± 9.5 mmHg, respectively, p < 0.001), without affecting the heart rate. Moreover, neferine (10−12 − 10−4 M) exhibited concentration-dependent vasorelaxation in endothelium-intact rings (Emax values = 98.95 ± 0.66% and pD2 = 7.93 ± 0.28) and endothelium-denuded rings (Emax values = 90.61 ± 1.91% and pD2 = 6.85 ± 0.36). The effects of neferine were reduced by pre-incubation with L-NAME and 1H-[1,2,4]oxadiazolo[4,3-a] quinoxalin-1-one (ODQ) but not with pre-incubation with indomethacin and K+channel blockers. Neferine attenuated the contractions induced by phenylephrine and caffeine in a Ca2+-free solution and also inhibited in CaCl2- and phenylephrine-induced contracted rings. Our study suggests that neferine exhibited hypertensive potential, induced vasorelaxation through the endothelium nitric oxide synthase (eNOS)/nitric oxide (NO)/soluble guanylyl cyclase (sGC) pathway and involved the modulation of Ca2+ influx through Ca2+ channels and intracellular Ca2+ release from the sarcoplasmic reticulum.
Drug Leads from Endophytic Fungi: Lessons Learned via Scaled Production
Authors: Graf Tyler N. , Kao Diana , Rivera-Chávez José , Gallagher Jacklyn M. , Raja Huzefa A. , Oberlies Nicholas H.
Published: March 2020

Recently, the isolation and elucidation of a series of polyhydroxyanthraquinones were reported from an organic extract of a solid phase culture of an endophytic fungus, Penicillium restrictum (strain G85). One of these compounds, ω-hydroxyemodin (1), showed promising quorum-sensing inhibition against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA) in both in vitro and in vivo models. The initial supply of 1 was 19 mg, and this amount needed to be scaled by a factor of 30 to 50 times, in order to generate material for further in vivo studies. To do so, improvements were implemented to enhance both the fermentation of the fungal culture and the isolation of this compound, with the target of generating > 800 mg of study materials in a period of 13 wk. Valuable insights, both regarding chemistry and mycology, were gained during the targeted production of 1 on the laboratory-scale. In addition, methods were modified to make the process more environmentally friendly by judicious choice of solvents, implementing procedures for solvent recycling, and minimizing the use of halogenated solvents.
Palladium/Norbornene Chemistry in the Synthesis of Polycyclic Indolines with Simple Nitrogen Sources
Authors: Jafarpour Farnaz , Habibi Azizollah , Ghasemi Mehran
Published: March 2020

An efficient procedure has been developed to synthesize ­indoline derivatives through a palladium-catalyzed Heck reaction/C–H activation/dual amination cascade in one pot. This constitutes the first intermolecular catalytic approach to directly access N-alkylindolines with a broad substrate scope in the absence of any ligands. This method highlights the use of readily available amines and ureas as the required nitrogen sources in building up the indoline core.
Acetic Anhydride–Acetic Acid as a New Dehydrating Agent of Aldoximes for the Preparation of Nitriles: Preparation of 2-Cyanoglycals
Authors: Kinfe Henok H. , Mabasa Tommy F. , Mabasa Jackie , Simelane Mthokozisi , Vatsha Banele , Makhubela Banothile C.E.
Published: March 2020

Glycals, 1,2-unsatrated carbohydrates, are versatile building blocks for the synthesis of various scaffolds. Despite their potential to serve as suitable precursors in diversity-oriented synthesis, 2-cyanoglycals are less explored in terms of their synthesis and derivatization. Herein, we report a combination of Ac2O and AcOH as new and efficient dehydrating agent of aldoximes for the synthesis of 2-cyanoglycals. In comparison to the conventional dehydrating system of Ac2O-base (such as NaOH, NaOAc and K2CO3), the current protocol provides superior yields and faster reaction rates. The scope and limitations of the dehydrating system are investigated.
Oxidative Rearrangement via 1,2-Aryl Migration using Hydroxy(tosyloxy)iodobenzene in a Polar Aprotic Solvent
Authors: Kamal Raj , Kumar Vipan , Kumar Ravinder , Saini Sangeeta , Kumar Rajesh
Published: March 2020

A series of geminal β,β-ditosyloxy ketones were synthesized in moderate to good yields through hydroxy(tosyloxy)iodobenzene-mediated ditosyloxylation of readily accessible α,β-unsaturated ketones in a polar aprotic solvent. A mechanism has been proposed for the synthesis of the geminal β,β-ditosyloxy ketones, and entails an oxidative rearrangement involving a 1,2-aryl migration.
National Institutes of Health (NIH) grant awards: does past performance predict future success?
Authors: Prasad Joni M. , Shipley Michael T. , Rogers Terry B. , Puche Adam C.
Published: March 2020

The NIH is the major federal biomedical research funding agency within the United States, and NIH funding has become a priority in institutional decisions on faculty recruitment, salary, promotion, and tenure. The implicit assumption is that well-funded investigators will maintain their funding success; however, our analysis of NIH awardees from 2000 to 2015 suggests that regardless of how well funded an investigator is, their research portfolio exhibits “regression to the mean,” matching the typical NIH funding profile within just 10–15 years. Thus, outperformance in past funding is not a strong predictor of future outperformance in funding success. This study indicates that faculty performance should not be solely judged upon grant success but should include other institutional mission priorities such as provision of clinical care, education, and service to community/profession.
Macroscopic and edge behavior of a planar jellium
Authors: Chafaï Djalil , García-Zelada David , Jung Paul
Published: March 2020

We consider a planar Coulomb gas in which the external potential is generated by a smeared uniform background of opposite-sign charge on a disk. This model can be seen as a two-dimensional Wigner jellium, not necessarily charge-neutral, and with particles allowed to exist beyond the support of the smeared charge. The full space integrability condition requires a low enough temperature or high enough total smeared charge. This condition does not allow, at the same time, total charge-neutrality and determinantal structure. The model shares similarities with both the complex Ginibre ensemble and the Forrester–Krishnapur spherical ensemble of random matrix theory. In particular, for a certain regime of temperature and total charge, the equilibrium measure is uniform on a disk as in the Ginibre ensemble, while the modulus of the farthest particle has heavy-tailed fluctuations as in the Forrester–Krishnapur spherical ensemble. We also touch upon a higher temperature regime producing a crossover equilibrium measure, as well as a transition to Gumbel edge fluctuations. More results in the same spirit on edge fluctuations are explored by the second author together with Raphael Butez.
Vortex-induced vibrations of a confined circular cylinder for efficient flow power extraction
Authors: Soti Atul Kumar , De Ashoke
Published: March 2020

The effects of confinement on vortex-induced vibration (VIV) of a circular cylinder (diameter D) and its flow power extraction capability are presented. A two-dimensional numerical study is performed on VIV of a circular cylinder inside a parallel plate channel of height H at Reynolds numbers 100 and 150. The blockage ratio (b = D/H) is varied from 1/4 to 1/2. The cylinder is elastically mounted with a spring such that it can only vibrate transversely to the flow. It has a fixed non-dimensional mass (m*) of 10. The energy extraction process is modeled as a damper (damping ratio ζ) attached to the cylinder. With increasing blockage, the vibration amplitude of the cylinder decreases, the lock-in happens at a larger non-dimensional natural frequency of the cylinder, and the initial branch of the vibration response of the cylinder shrinks. There is a minimum value of the channel height and Reynolds number for the existence of the initial branch. The extracted power is found to increase rapidly with the blockage. For the maximum blockage (b = 1/2), the flow power extracted by the cylinder is an order of magnitude larger as compared to what it would extract in an open domain with free stream velocity equal to the channel mean velocity. The optimal mass-damping (α = m*ζ) for extracting the maximum power is found to lie between 0.2 and 0.3. An expression is derived to predict the maximum extracted power from the undamped response of a confined/unconfined cylinder.
A multiplex, multi-timescale model approach for economic and frequency control in power grids
Authors: Strenge Lia , Schultz Paul , Kurths Jürgen , Raisch Jörg , Hellmann Frank
Published: March 2020

Power systems are subject to fundamental changes due to the increasing infeed of decentralized renewable energy sources and storage. The decentralized nature of the new actors in the system requires new concepts for structuring the power grid and achieving a wide range of control tasks ranging from seconds to days. Here, we introduce a multiplex dynamical network model covering all control timescales. Crucially, we combine a decentralized, self-organized low-level control and a smart grid layer of devices that can aggregate information from remote sources. The safety-critical task of frequency control is performed by the former and the economic objective of demand matching dispatch by the latter. Having both aspects present in the same model allows us to study the interaction between the layers. Remarkably, we find that adding communication in the form of aggregation does not improve the performance in the cases considered. Instead, the self-organized state of the system already contains the information required to learn the demand structure in the entire grid. The model introduced here is highly flexible and can accommodate a wide range of scenarios relevant to future power grids. We expect that it is especially useful in the context of low-energy microgrids with distributed generation.
Epitaxial growth of Cu2ZnSnS4 thin film on Si by radio frequency magnetron sputtering
Authors: Song Ning , Green Martin A. , Sun Kaiwen , Hu Yicong , Yan Chang , Hao Xiaojing
Published: March 2020

Environmentally friendly and earth abundant Cu2ZnSnS4 (CZTS) based thin films are potential absorbers for next generation photovoltaics. Their optical properties provide the option to be used as upper cells for Si based tandem solar cells, together with a similar structure to Si, triggering interest in investigation of CZTS/Si tandem cells. However, epitaxially growing CZTS on Si can be challenging. Here, we heteroepitaxially grow tetragonal Cu2ZnSnS4 (CZTS) thin films on single crystalline cubic Si (111) wafers with a 4° miscut by simple and low-cost radio frequency magnetron sputtering from a single target. The CZTS film displays a mirror-like surface with a surface roughness of 8.46 nm. The absorption coefficients of the epitaxial CZTS are over 104 cm−1 at 1.5 eV and 1.0 × 105 cm−1 at 2.1 eV. The bandgap is 1.45 eV, and the photoluminescence lifetime is 7.04 ns. Our results demonstrate the potential of the epitaxial CZTS films fabricated by sputtering on the Si substrate for application in CZTS/Si based tandem solar cells.
Oxygen vacancies: The (in)visible friend of oxide electronics
Authors: Gunkel F. , Christensen D. V. , Chen Y. Z. , Pryds N.
Published: March 2020

Oxygen vacancies play crucial roles in determining the physical properties of metal oxides, representing important building blocks in many scientific and technological fields due to their unique chemical, physical, and electronic properties. However, oxygen vacancies are often invisible because of their dilute concentrations. Therefore, characterizing and quantifying their presence is of utmost importance for understanding and realizing functional metal oxide devices. This, however, is oftentimes a non-trivial task. In this Perspective paper, we discuss the relevant regimes of concentrations and associated phenomena arising from oxygen vacancies. We then focus on experimental techniques available for observing oxygen vacancies at widely different levels of concentrations. Finally, we discuss current challenges and opportunities for utilizing oxygen vacancies in metal oxides.
Numerical study of a broadband metamaterial absorber using a single split circle ring and lumped resistors for X-band applications
Authors: Nguyen Thi Quynh Hoa , Nguyen Thi Kim Thu , Cao Thanh Nghia , Nguyen Hugo , Bach Long Giang
Published: March 2020

We report a numerical study on the design of a broadband metamaterial absorber (MMA) with a single layer of metal–dielectric–metal based on an FR-4 substrate for X-band applications. The MMA structure consists of a periodic array of a split circle ring and lumped resistors coupled within split segments. The MMA structure achieves a broadband absorption response in the frequency range of 7.8–12.6 GHz with an absorptivity of above 90% under normal incidence for all polarization angles. The absorptivity remains above 70% in the frequency range of 6.8–11.8 GHz at wide incident angles from 0° to 30° for both transverse electric and transverse magnetic polarizations. The physical mechanism of the absorber is explained by the electric and the surface current distributions that, in turn, are significantly affected by magnetic resonance.
Unconventional picosecond strain pulses resulting from the saturation of magnetic stress within a photoexcited rare earth layer
Authors: von Reppert A. , Mattern M. , Pudell J.-E. , Zeuschner S. P. , Dumesnil K. , Bargheer M.
Published: March 2020

Optical excitation of spin-ordered rare earth metals triggers a complex response of the crystal lattice since expansive stresses from electron and phonon excitations compete with a contractive stress induced by spin disorder. Using ultrafast x-ray diffraction experiments, we study the layer specific strain response of a dysprosium film within a metallic heterostructure upon femtosecond laser-excitation. The elastic and diffusive transport of energy to an adjacent, non-excited detection layer clearly separates the contributions of strain pulses and thermal excitations in the time domain. We find that energy transfer processes to magnetic excitations significantly modify the observed conventional bipolar strain wave into a unipolar pulse. By modeling the spin system as a saturable energy reservoir that generates substantial contractive stress on ultrafast timescales, we can reproduce the observed strain response and estimate the time- and space dependent magnetic stress. The saturation of the magnetic stress contribution yields a non-monotonous total stress within the nanolayer, which leads to unconventional picosecond strain pulses.
Local spectra at impurity and neighboring sites in graphene: Resonance manifestation
Authors: Skrypnyk Y. V. , Loktev V. M.
Published: March 2020

The electronic spectrum of graphene with a single point impurity is considered. Local densities of states at the impurity site and its nearest neighbors are calculated analytically. Their evolution with increasing the impurity potential is examined. It is shown that in the domain of the well-defined impurity resonance the local density of states at the first-nearest neighbor of the impurity site is approximately a scaled-up copy of the local density of states at the impurity site. The corresponding factor is found to be proportional to the squared impurity potential.