bluuebunny/crossref_metadata_2025 huggingface dataset:
Bacteriophage T4 Head: Structure, Assembly, and Genome Packaging
Authors: Rao Venigalla B. , Fokine Andrei , Fang Qianglin , Shao Qianqian
Published: February 2023

Bacteriophage (phage) T4 has served as an extraordinary model to elucidate biological structures and mechanisms. Recent discoveries on the T4 head (capsid) structure, portal vertex, and genome packaging add a significant body of new literature to phage biology. Head structures in unexpanded and expanded conformations show dramatic domain movements, structural remodeling, and a ~70% increase in inner volume while creating high-affinity binding sites for the outer decoration proteins Soc and Hoc. Small changes in intercapsomer interactions modulate angles between capsomer planes, leading to profound alterations in head length. The in situ cryo-EM structure of the symmetry-mismatched portal vertex shows the remarkable structural morphing of local regions of the portal protein, allowing similar interactions with the capsid protein in different structural environments. Conformational changes in these interactions trigger the structural remodeling of capsid protein subunits surrounding the portal vertex, which propagate as a wave of expansion throughout the capsid. A second symmetry mismatch is created when a pentameric packaging motor assembles at the outer “clip” domains of the dodecameric portal vertex. The single-molecule dynamics of the packaging machine suggests a continuous burst mechanism in which the motor subunits adjusted to the shape of the DNA fire ATP hydrolysis, generating speeds as high as 2000 bp/s.
Patients with SARS-CoV-2-Induced Viral Sepsis Simultaneously Show Immune Activation, Impaired Immune Function and a Procoagulatory Disease State
Authors: Limmer Andreas , Engler Andrea , Kattner Simone , Gregorius Jonas , Pattberg Kevin Thomas , Schulz Rebecca , Schwab Jansje , Roth Johannes , Vogl Thomas , Krawczyk Adalbert , Witzke Oliver , Zelinskyy Gennadiy , Dittmer Ulf , Brenner Thorsten , Berger Marc Moritz
Published: February 2023

Background: It is widely accepted that SARS-CoV-2 causes a dysregulation of immune and coagulation processes. In severely affected patients, viral sepsis may result in life endangering multiple organ dysfunction. Furthermore, most therapies for COVID-19 patients target either the immune system or coagulation processes. As the exact mechanism causing SARS-CoV-2-induced morbidity and mortality was unknown, we started an in-depth analysis of immunologic and coagulation processes. Methods: 127 COVID-19 patients were treated at the University Hospital Essen, Germany, between May 2020 and February 2022. Patients were divided according to their maximum COVID-19 WHO ordinal severity score (WHO 0–10) into hospitalized patients with a non-severe course of disease (WHO 4–5, n = 52) and those with a severe course of disease (WHO 6–10, n = 75). Non-infected individuals served as healthy controls (WHO 0, n = 42). Blood was analyzed with respect to cell numbers, clotting factors, as well as pro- and anti-inflammatory mediators in plasma. As functional parameters, phagocytosis and inflammatory responses to LPS and antigen-specific stimulation were determined in monocytes, granulocytes, and T cells using flow cytometry. Findings: In the present study, immune and coagulation systems were analyzed simultaneously. Interestingly, many severe COVID-19 patients showed an upregulation of pro-inflammatory mediators and at the same time clear signs of immunosuppression. Furthermore, severe COVID-19 patients not only exhibited a disturbed immune system, but in addition showed a pronounced pro-coagulation phenotype with impaired fibrinolysis. Therefore, our study adds another puzzle piece to the already complex picture of COVID-19 pathology implying that therapies in COVID-19 must be individualized. Conclusion: Despite years of research, COVID-19 has not been understood completely and still no therapies exist, fitting all requirements and phases of COVID-19 disease. This observation is highly reminiscent to sepsis. Research in sepsis has been going on for decades, while the disease is still not completely understood and therapies fitting all patients are lacking as well. In both septic and COVID-19 patients, immune activation can be accompanied by immune paralysis, complicating therapeutic intervention. Accordingly, therapies that lower immune activation may cause detrimental effects in patients, who are immune paralyzed by viral infections or sepsis. We therefore suggest individualizing therapies and to broaden the spectrum of immunological parameters analyzed before therapy. Only if the immune status of a patient is understood, can a therapeutic intervention be successful.
Aspects of Phage-Based Vaccines for Protein and Epitope Immunization
Authors: Palma Marco
Published: February 2023

Because vaccine development is a difficult process, this study reviews aspects of phages as vaccine delivery vehicles through a literature search. The results demonstrated that because phages have adjuvant properties and are safe for humans and animals, they are an excellent vaccine tool for protein and epitope immunization. The phage genome can easily be manipulated to display antigens or create DNA vaccines. Additionally, they are easy to produce on a large scale, which lowers their manufacturing costs. They are stable under various conditions, which can facilitate their transport and storage. However, no medicine regulatory agency has yet authorized phage-based vaccines despite the considerable preclinical data confirming their benefits. The skeptical perspective of phages should be overcome because humans encounter bacteriophages in their environment all the time without suffering adverse effects. The lack of clinical trials, endotoxin contamination, phage composition, and long-term negative effects are some obstacles preventing the development of phage vaccines. However, their prospects should be promising because phages are safe in clinical trials; they have been authorized as a food additive to avoid food contamination and approved for emergency use in phage therapy against difficult-to-treat antibiotic-resistant bacteria. Therefore, this encourages the use of phages in vaccines.
First record of the pan-tropical Yellow Water Pea Vigna luteola (Fabaceae) seed from a NW European shore
Authors: Minchin Dan , Hill Rosemary , Lewis Gwilym
Published: February 2023

The first record of a seed of the Yellow Water Pea Vigna luteola (Jacq.) Benth. stranded in Northwest Europe was collected along with other trans-Atlantic disseminules from a south-west facing beach in County Kerry, Ireland (v.c.H1) during March 2022.
Analysing changes in physiological response to different soundscape scenarios.
Authors: Manohare Manish , Rajasekar Elangovan , Oberman Tin , Aletta Francesco , Kang Jian , Parida Manoranjan
Published: February 2023

Noise pollution is one of the key environmental stressors leading to multiple health impacts for people and communities. Exposure to high noise levels may also be responsible for sudden emotional and physiological changes in humans. The experiment examines the change in Galvanic Skin
Response (GSR) signals during exposure to pre-recorded soundscape scenarios. These scenarios were recorded in New Delhi, India and London, UK, using a binaural microphone set. The listening experiment was conducted in a laboratory, where 24 healthy individuals without any hearing impairment
or any psychological issues participated. A total of 30 soundscape scenarios were presented to each participant in a randomised order. The continuous decomposition analysis is conducted to decompose that data into tonic and phasic components. The phasic component of the signal is used for
the analysis. It is observed that skin conductance response (SCR) increases with changes in the overall loudness of the signal. Psychoacoustic indicators are used to identify the relationship between different acoustical characters of noise and changes in SCR. The perception-based survey suggests
that GSR response is highly dependent on the pleasantness level of the soundscape scenario.
Effects of noise and vibration on operatives with machine interaction in manufacturing environments
Authors: Buono Mario , Bevilacqua Antonella , Capece Sonia , Lombardi Ilaria
Published: February 2023

Human-machine interaction is an ordinary paradigm in the manufacturing industry. This area of business has to ensure high standard of safety levels in order to protect the operatives while performing their tasks. If the safety criteria are not met nor controlled, psychological disease
and physical injuries can be developed in the working environments. The effects could lead to short or long-term diseases such as tinnitus or hearth attacks, based on the levels of stress. During the last decades, different methodologies have been developed to analyse and evaluate the parameters
linked to the human-machine interaction. These methodologies include the biomechanics overload, noise and vibration. This paper deals with a case study as representative of the manufacturing sector. The noise and vibration levels of different machines have been extracted by a database of been
measured on site by using a class 1 sound level meter. The purpose of the paper is to make a data analysis, assuming a long-term projection of the physical and psychological effects that could affect the operatives in case any criteria has not been met.
Experimental investigation on a side-by-side twin rotor system in pusher configuration
Authors: De Paola Elisa , Di Marco Alessandro , Stoica Luana Georgiana , Falcini Leonardo , Camussi Roberto
Published: February 2023

Growing interest in electric propulsion, together with the increased deployment of unmanned aerial vehicles, results in the consequent need for a clear understanding of the physical phenomena under propeller interactions which represent a primary noise source in multi-rotor configurations.
To this purpose, the effect of rotor-to-rotor interactions of a twin pusher propeller configuration at static thrust conditions was experimentally investigated through aerodynamic and aeroacoustic measurement campaigns. The propellers tested refer to the APC-8x45MR rotor with an 8 inches diameter.
The aerodynamics and aeroacoustics of several configurations were investigated using PIV technique, Pitot tube acquisitions, and microphone measurements performed in an anechoic environment. The propeller speed was varied within a typical range in the applications for both co-rotating and
counter-rotating layouts. To define critical relative positions, many tip-to-tip separation distances were considered highlighting the general effects. Owing to the deformation exhibited by the rotor wakes due to their proximity, the pressure and velocity signals were conditioned to inspect
the driving mechanisms responsible for the noise emission. Results provide a deeper insight into the physics involved and show different types of interaction effects on the fluid-dynamic field as a function of the propeller position, allowing the identification of the main critical configurations.
State of the art about solutions for tram noise reduction in the framework of the Life SNEAK project
Authors: Megna Gianluca , Governi Lapo , Carfagni Monica , Borchi Francesco , Puggelli Luca , Buonamici Francesco
Published: February 2023

The LIFE SNEAK project, started in September 2021, aims at the reduction of noise from road traffic that mainly affects densely populated urban areas where the noise and vibrations produced by the tram overlap with noise produced by road traffic. Applicative measures will be designed
and tested in a pilot case of the city of Florence, such as low-noise and vibration surfaces, with life cycle costs comparable to those of traditional surfaces, and measures to reduce tram noise aiming to obtain substantial reductions in noise and annoyance. Referring to tram noise, in the
first phase of the project, specific attention has been dedicated to the state-of-the-art analysis concerning possible measures to perform noise reduction with specific attention to noise due to wheel-rail contact and "squeal noise" phenomena that mainly occur in urban environments
close to curves with small radius. In this paper, the results of the state-of-the-art analysis are presented with particular attention to the use of sound-absorbing panels to be applied on the tram (bogie skirts).
Ultrafast Miniature Robotic Swimmers with Upstream Motility
Authors: Wang Yibin , Chen Hui , Law Junhui , Du Xingzhou , Yu Jiangfan
Published: February 2023

With the development of materials science and micro–nano fabrication techniques, miniature soft robots at millimeter or submillimeter size can be manufactured and actuated remotely. The small-scaled robots have the unique capability to access hard-to-reach regions in the human body in a noninvasive manner. To date, it is still challenging for miniature robots to accurately move in the diverse and dynamic environments in the human body (e.g., in blood flow). To effectively locomote in the vascular system, miniature swimmers with upstream swimming capability are required. Herein, we design and fabricate a miniature robotic swimmer capable of performing ultrafast swimming in a fluidic environment. The maximum velocity of the swimmer in water is 30 cm/s, which is 60 body lengths. Moreover, in a tubular environment, the swimmer can still obtain a swimming velocity of 17 cm/s. The swimmer can also perform upstream swimming in a tubular environment with a velocity of 5 cm/s when the flow speed is 10 cm/s. The ultrasound-guided navigation of the swimmer in a phantom mimicking a blood vessel is also realized. This work gives insight into the design of agile undulatory milliswimmers for future biomedical applications.
High-Precision Fast Direction-of-Arrival Estimation Method for Planar Array
Authors: Li Shuai , Li Lei , Liu Bo , Song Yihao , Li Ming , Ren Jie , Jiang Wenting
Published: February 2023

The multiple signal classification method for direction-of-arrival estimation is widely applied in practical scenarios. However, the multiple signal classification method with planar array requires 2-dimensional on-grid spectrum searches, which would lead to the grid mismatch and high computational complexity. Therefore, a high-precision fast direction-of-arrival estimation method for planar array is proposed. In the proposed method, a 2-stage grid search approach over the 2-dimensional spectrum is firstly applied to obtain a quick coarse estimation of direction of arrival. Then, the estimation of higher precision is achieved via a quadratic surface fitting method. Simulation results verified the effectiveness of the proposed method.
DOES CORPORATE SOCIAL RESPONSIBILITY IMPROVE COMMUNITY SATISFACTION?
Authors: Yuliani Rahma , Mubarak Zaki , Arifah Arifah
Published: February 2023

Corporate Social Responsibility is a form of corporate responsibility to stakeholders. PT. Pertamina Patra Niaga Fuel Terminal Tarakan developed a mangrove conservation ecotourism program to avoid degradation in the area by involving the surrounding community. This study aims to find out whether CSR programs improve community satisfaction. The research uses quantitative and qualitative approaches. The analysis used the Community satisfaction index (CSI) with 12 question indicators. The research sample comprised 30 community respondents in the Tanjung Batu area, Mamburungan Village, Tarakan City District. The results showed that the CSI value is 3.25, which after conversion got a value of 81.25, was in the range of 62.51-81.25 in the "GOOD" category with a quality value of "B". This result indicates that the community very welcomes the CSR program.
ASSESSMENT OF WETLAND DEGRADATION CONDITION AND TREND BASED ON LAND USE/COVER IN WAMI-RUVU RIVER BASIN USING MULTI-TEMPORAL LANDSAT IMAGES
Authors: Kimario Edina P. , Mbilinyi Boniface , Hieronimo Proches
Published: February 2023

The understanding of wetlands’ distribution and their level of susceptibility is important to enhance management and conservation efforts. The study aimed to map wetlands and assess their distribution pattern and their degradation based on the LULC by the years 2000, 2010 and 2020. Wetland types i.e., marshes, ponds, lakes, fens, rivers, floodplains, swamps, and open water bodies with other land use such as agriculture land, built-up and natural vegetation land were classified and mapped using random forest algorithm in Arc Map. Multi-temporal Landsat satellite data including thematic Mapper Landsat (+ETM) and Operational Land Imager (OLI) images were used for LULC mapping. The random forest classifier technique is used to analyse the satellite imagery for detecting the LULC changes during the whole study period. To assess the wetland area degradation three aspects were used in this study for the analysis; wetland area change rate, annual land cover change and annual land cover change rate. The study found about -34.41Km2/y of wetlands potentially are degraded annually due to human and natural stressors in 20 years of our study however the basin experienced a higher rate of wetland degradation in the second epoch of 2010-2020 where the basin experience -42.8Km2/y degradation which results to the total loss of -687.75 km2 total coverage of wetland area in the basin. This information could be used to improve wetland planning and management by wetland managers and other stakeholders.
FACTORS INFLUENCING ADOPTION OF SELECTED PADDY INNOVATIONS AMONG SMALLHOLDER FARMERS IN MVOMERO DISTRICT, TANZANIA
Authors: Mhango Solomon S.
Published: February 2023

Adoption of paddy innovations is important for production and productivity but there has been low or non adoption at different places in Tanzania. Despite this adoption of innovations has not been convincing. This research was conducted in Mvomero District, Morogoro, Tanzania to determine the extent of adoption of innovations in paddy production and analyzed factors influencing this adoption. A cross-sectional research design was adopted and 299 respondents were sampled using simple random technique. Data were collected using questionnaire, in-depth interviews, field observation and Focus Group Discussions (FGDs). Qualitative data were analyzed using content analysis. Binary logistic regression analysis was used to estimate factors influencing adoption of innovations. The study concludes that, it is difficult for a smallholder paddy farmer to attain full adoption of an innovation package which composes several practices in it as it become complex to follow. Extension programmes including trainings on introduced innovations and regular visits are important for adoption of paddy innovations to rural farmers. Markets availability is an opportunity which motivates farmers to adopt paddy innovations. Therefore, farmers should be well-informed of the markets by the extension and marketing officers.
HYBRID CORN SEED PRODUCTION WITH STRAIGHT AND RECIPROCAL CROSSING COMBINATION FORMS IN CASE OF SOME MV HYBRIDS
Authors: Sándo Záborszky , Tamás Berzy
Published: February 2023

ABSTRACT The selection of optimal parental lines are very important – at hybrid corn seed production. Correlation between the seedling length, high seed vigour ratio, and emergence during suboptimal environmental conditions are high. The higher-yielding ability is the most important thing, point of view as a financial factor. After examination, the seed biological value (germination, and vigour laboratory tests) the seed lots of 21 maize genotypes, with different straight and reciprocal combinations were studied at field experiments, between 2020-2022. We can emphasize: there are differences between the different crossing combinations. The fresh shoot weight of maize seedlings developing in a cold, oxygen poor environmental conditions was greater than the fresh root weight for the genotypes, regardless of the crossing methode. The plants developing from seeds with greater seed vigour; exhibited better emergence, faster ripening and lower grain moisture at harvest ( H 05 x RPK, H 70 x RPK, H 06 x US, H 06 x H 44, H 06 x TG, H 72 x H 29, H 06 x H 49, GS 21 x H 35, GS 22 x H 35). Correlation between the high vigour seedlings - for plants developing from seed lots from reciprocal crossing combinations-and fresh shoot weight of the seedlings and the kernel yield, were obvious – Marco, Kadricorn, Ghurkan, Koramag, Marfi, Mv 633, Mv Exp 21, and Mv 401- 21 hybrids. Importance of selection the best crossing ( yielding ability) combinations as the same – like importance of seed biological value.
Assessment of STI dry etch process variability by means of dynamic time warping technique
Authors: Milenin Alexey P. , Chan BT , Lazzarino Frederic
Published: February 2023

Numerical data of two in situ optical acquisition systems were used in machine learning algorithm to evaluate an shallow trench isolation dry etch process in a dataset of more than 200 etched wafers processed during a year. Though overall recipe performance was according to specifications, the observed parameter fluctuations were characterized to check for correlation patterns in processing data by means of machine learning. Thus, dynamic time wrapping was used to analyze time series datasets to get characteristics of minimum distance’s path between signals coming of each individual wafer. Such metrics of distances could help clustering groups of wafers that appear to be in proximity. Out of eight analyzed channels, we observed the largest distance variability was in the Si main etch for spectral reflectometer dataset, which we compared to optical emission spectroscopy channels. Based on correlation assessment of distances to the etch depth uniformity data, we showed that the selected approach is a good means to analyze time series datasets of e.g. dry etch processes for monitoring process stability.
Methodological approaches to assessing the tourism investment attractiveness of the Arctic regions of Russia
Authors: Kurochkina A. A. , Semenova Yu. E. , Ostrovskaya E. N.
Published: February 2023

Aim. The presented study aims to develop a new methodological approach to assessing the tourism investment attractiveness of the Arctic regions of Russia.

Tasks. The authors formulate criteria reflecting the most important factors of investment attractiveness for potential investors; develop a methodology for comprehensively assessing the tourism investment attractiveness of a particular region for investors and comparing different regions against each other.

Methods. The materials used for the study include the legislation of the Russian Federation, acts of the Government of the Russian Federation and regulatory documents, scientific articles and monographs on the problems of investment in the tourism industry. The methodological basis of the study comprises the principles and provisions of the dialectical and systems approaches, methods of analysis and synthesis, induction and deduction, analogy, comparison and generalization, classification, economic and mathematical modeling, empirical data processing and graphical representation of results, expert and statistical methods.

Results. Modern tourism investment practices in Russia under current conditions are reviewed; a typology of economic entities serving as potential investors in the tourism industry is proposed; a model for assessing the tourism investment prospects of a territory (region) using a list of evaluation indicators is developed.

Conclusions. Tourism in the Arctic can be one of the drivers of the region’s economic development, which is why it is so important to attract investors to these territories and, consequently, to develop methodological approaches to assessing tourism investment attractiveness that both investors and local authorities could use. It is concluded that assessing the investment attractiveness of destinations in the Arctic region requires a special methodology due to the uniqueness of this territory.
Standardization in the formation of sustainable regional development
Authors: Antonov V. S.
Published: February 2023

Aim. The presented study aims to analyze the existing system of regulation of economic relations between regional subjects in the context of the issues of global resource conservation and to develop proposals for the formation of a regional standardization system. Tasks. The authors analyze current regulations in the Republic of Tatarstan and the Republic's experience of creating and implementing regional standards in the field of resource conservation; formulate proposals for the formation of a regional standardization system based on territorial standardization bodies focusing on collecting and generalizing the region's best practices in the field of resource conservation and adaptation of third-party standardization documents to the specifics of the Republic of Tatarstan.Methods. This study is based on the paradigm of sustainable regional development. This paradigm encapsulates an integrated approach to the formation of a territorial management system, the principles of continuous improvement and minimization of the variability of management processes through standardization.Results. Based on the performed analysis of the regulatory and legal framework of regional management processes, an algorithm for the development of a regional standardization system is proposed, aimed at the formation of approaches and tools for sustainable territorial development. The goals and objectives of an authorized regional standardization body are formulated.Conclusions. The sectoral and target subsystems of the "Lean Region" spatial model determine the vector of regional standardization. Considering the specifics of economic development in the Republic of Tatarstan, major directions of regional standardization are identified: petrochemical, machine-building, and agricultural industries, elements of industrial and social infrastructure.
Priorities and directions of national development in supporting non-resource exports
Authors: Anosova L. A. , Kabir L. S.
Published: February 2023

Aim. The presented study aims to assess the process of formation and implementation of strategic priorities and directions in supporting non-resource exports from the perspective of achieving the country’s sustainable economic development.Tasks. The authors analyze and evaluate the existing system of strategic planning for the development of non-resource exports in Russia and the established system of institutions supporting national non-resource exports.Methods. This study examines strategic planning documents developed at the federal level for industries considered by the Russian Export Center as exporters of non-resource goods, works, and services. An analysis of federal sectoral strategies is complemented by an analysis of strategic planning documents developed by the regions of the Russian Federation. The goal is to determine how one of the most important issues of increasing non-resource exports is being integrated into the problems of the country’s socio-economic development.Results. Federal, sectoral, and regional strategic documents used to provide institutional support for the export strategy are assessed based on the conducted research. An information and analytical base is being formed to systematize data on the consistency between socio-economic development objectives at the federal and regional level and tools for supporting non-resource exports in Russia.Conclusions. Today, strategic planning of the country’s development faces the risk of institutional support for non-resource export priorities being insufficient for the purposes of solving the tasks of socio-economic development of the Russian Federation. Furthermore, there is a situation when the system of measures of government support for non-resource exports is not based on regional territorial structure, but rather exists in parallel with it. It is necessary to update the national export strategy, identifying the components of non-resource exports in it, and to integrate strategic plans developed at the federal level into regional development strategies.
Diagnostics-oriented Model for Automotive SCR-ASC
Authors: Jain Kaushal Kamal , Meckl Peter , Chen Pingen , Yang Kuo
Published: February 2023

This paper presents a diagnostics-oriented aging model for combined Selective Catalytic Reduction (SCR) and Ammonia Slip Catalyst (ASC) system, along with a model-based on-board diagnostic (OBD) method applied to both test-cell data and on-road data from commercial trucks. The key challenge with model development was unavailability of NOx and NH3 measurements between SCR and ASC. Since it would have been very difficult to calibrate both SCR and ASC dynamics without any measurements between SCR and ASC, therefore ASC was modeled using static look-up tables to determine ASC’s NH3 conversion efficiency and its selectivity to NOx and N2O as a function of temperature and flow rate. The traditional three-state single-cell ordinary differential equation (ODE) model was used for SCR. Hot Federal Test Procedure (hFTP) was used to calibrate the model. Cold FTP (cFTP) and Ramped Mode Cycle (RMC) were used for validation. Results show that the SCR-ASC model can capture the aging signatures in tailpipe NOx, NH3, and N2O reasonably well for cFTP, hFTP, and RMC cycles in the testcell data. After slight re-calibration and combining with a simple model for commercial NOx sensor’s cross-sensitivity to NH3, the model works reasonably well for on-road data from commercial trucks. A model-based on-board diagnostic (OBD) method has been presented with enable conditions designed to detect operating conditions suitable for detecting aging signatures, while minimizing false positives and false negatives. The OBD method is applied to both test-cell and real-world truck data with commercial NOx sensors. Results on test-cell data demonstrate the challenges of robust SCR monitoring even on the limited data set used in this work. The model-based enable conditions are shown to be robust but extremely restrictive as the OBD gets enabled at very few points in the test-cell data. Application on truck data showed that the proposed OBD method can be implemented on commercial trucks with limited sensors. In the truck data, the enable conditions were satisfied on many more points than the test-cell data. Results on truck data show encouraging trends between relative degradation level and the number of miles on four trucks. In future work, these trends will be validated using more data from commercial trucks with known aging levels.
DORSAL ARACHNOID WEB IN THORACIC SPINE: A CASE REPORT
Authors: Mahajan Suvanya , Katal Shivani , Pandita Pamposh , Sharma Rajesh
Published: February 2023

Dorsal arachnoid web is a rare entity, which was rst reported by Malleci et al in 1997.It represents intradural,
extramedullary band of arachnoid tissue that extends to the pial surface of the spinal cord which blocks the cerebrospinal
uid ow in the longitudinal direction and widens the dorsal cerebrospinal uid space associated with increased pressure of the cerebrospinal uid
& a local mass effect, resulting in the dorsal indentation and anterior displacement of the cord to cause myelopathy. Dorsal arachnoid web typically
occurs in the upper thoracic spine
EFFECTIVENESS SUPER BRAIN YOGA ON SHORT TERM MEMORY & SELECTIVE ATTENTION AMONG THE SCHOOL STUDENTS
Authors: Tripathy Karisma
Published: February 2023

Background: “Superbrain Yoga is a simple and effective technique to energize & recharge the brain.It is based on the
principles of subtle energy & ear acupuncture.”(Master Choa Kok Sui, World Pranic Healing Foundation, India Research
Centre). A Pre experimental research design was Undertaken with 50 Students(7-10 ye Methods: ar) by using Non probability Convenient
Sampling at Somanath Sikhya Niketan, Sameigadia ,Bhubaneswar . Effectiveness of Super brain yoga on short term memory and selective
attention among school students is assessed by using digit span test & six letter cancellation test respectively. Collected data were analyzed by
using descriptive and inferential statistics. Findings revealed that Maj Result: ority 36%(18) of school students were in the age group of 8-9
years, 32%(16) of school students were in the age group of 7-8 years and 32% (16) of school students were in the 9-10 years of age. 52% (26) of
school students were male and 48% (24) were female.Majority of school students 82% (41) were Hindu , Majority 38%(19) of school students
are in Std IV, 34% (17) of school students are in Std III & 28%(14) of school students are in Std V.52%(26) of school students belong to joint
family, 48% (24) of school students belong to nuclear family.The maximum percentage 42% of school students had the monthly family income
between 6327-18949, 36% . Highly signicant ,difference was found between pre and post test score and no signicant, association was found
between knowledge scores in relation to demographic variables . From the ndings Conclusion: of this study super brain yoga was effective to
improve score on short term memory & selective attention. There is no signicant association between knowledge score of school students in
posttest when compared to the demographic variables .
UNCOMMON SALIVARY GLAND TUMORS: A CASE SERIES
Authors: Chakraborty Shobhik , Pachal Sumitava , Saha Gaurav
Published: February 2023

Salivary gland tumors are one of the rare entities having the annual incidence rate of 0.5 to 2 per 100,000 persons[7]. Majority of them are benign,
only 20% cases are malignant. They usually present as painless mass in the oral cavity or close to their anatomical location. The main challenge is to
differentiate between the benign and the malignant ones. Thus, various imaging modalities are used. Investigations such as ne needle aspiration
cytology and MRI scans provide some useful information, but most cases will require tissue diagnosis to come to a denitive conclusion. Hence,
biopsy or histopathological study of the surgically excised tissue is the gold standard for diagnosis. Benign tumour and early low-grade
malignancies can be adequately treated with surgery alone, while more advanced and high-grade tumour with regional lymph node metastasis will
require postoperative radiotherapy[11]. The role of chemotherapy remains largely palliative. In this article, we have presented a series of cases with
uncommon tumors involving the various salivary glands.
SERUM HOMOCYSTEINE LEVELAMONG YOUNG PATIENTS WITH CEREBROVASCULAR ACCIDENT
Authors: Rai Manish , Ch. Hazarika Sarat , Sarmah Binod , Das Monigopa
Published: February 2023

Background: Stroke is dened as a focal (or at times global) neurological impairment of sudden onset. In general, stroke in young includes
subjects falling under the age group of 15-45 years. It is more heterogeneous due to wide variety of possible underlying risk factors and etiologies.
Hyperhomocysteinemia leads to proliferation of vascular smooth muscles, which oxidatively damages the vascular endothelium and creates a
prothrombotic environment thus promoting carotid atherosclerosis, lacunar infarction, and increased risk of stroke. Methods: It is a hospital based
observational study including patients attending OPD/IPD at Departments of Medicine and Neurology, Assam Medical College and Hospital,
Dibrugarh, Assam over a period of one year (1st July 2021 to 30th June 2022). 90 rst ever stroke patients aged 15-45 years were included. Serum
sample was stored and homocysteine estimated by ELISA. Statistical differences was measured between various stroke groups using student t- test
and a p value of <0.05 was considered statistically signicant. Results: Mean age for all the cases was 39.43 ± 5.71 years. Male preponderance was
seen (55.55%). Majority of the stroke cases were haemorrhagic (56.66 %). The average serum homocysteine was higher in ischemic stroke
(35.14±10.85 μmol/L) than in haemorrhagic stroke (23.28±7.58 μmol/L) ( p-value of 0.0279) Conclusions: Routine inclusion of serum
homocysteine level estimation in young patients with stroke is strongly suggested to assess the risk of stroke as well as measures should be taken
whenever necessary to reduce the homocysteine level to prevent various cerebrovascular complications.
Kajian Konsep Termodinamika Pada Air Purifier Sederhana
Authors: Putri Zulfira Dinda , Syahn Muhammad Meutuah i , Nurmasyitah Nurmasyitah
Published: February 2023

Pada kehidupan sehari-hari udara yang kita hirup ini sangat berpengaruh terhadap tubuh terlebih kesehatan manusia. Apabila kita menghirup udara yang tidak bersih atau kotor sudah jelas itu mengganggu aktivitas serta kesehatan tubuh, maka kita memerlukan alat yang dapat membantu meringankan hal tersebut agar aktivitas serta kesehatan dapat membaik. sehingga kita membutuhkan alat pembersih ruangan seperti Air Purifier. Tujuan dari percobaan dirancang perangkat Air Purifier agar udara yang terkontaminasi dapat tercegah, Kelebihan dari alat ini tentunya untuk membersihkan udara yang kotor seperti polusi yang berbeda-beda seperti asap rokok, Air purifier juga dapat menyaring udara kotor di kamar tidur, seperti bakteri, jamur, dan tungau debu, yang menyebabkan alergi dan gangguan tidur, rancangan Air Purifier ini menggunakan alat sensor berupa arduino esp 32 yaitu pendeteksi yang terhubung menggunakan wifi dan android melalui aplikasi yang berbasis IOT (Internet Of Things) yang cara kerjanya menggunakana jaringan kolektif yang terhubung, teknologi ini dapat mengfasilitasi penghitungan suhu udara dan jumlah udara kotor yang terkontiminasi.
Karakteristik penderita Gangguan Kecemasan Menyeluruh Pada Grave’s Disease dengan gambaran EKG Sick Sinus Syndrome (SSS)
Authors: Javier R. Mohamad , Rialdi Andisa Fadhila , Ahyandi Syarif Syamsi , Limanto Ericko Julian , Handika Ehwanul , Munir Badrul , Chandrawati Pertiwi Febriana , Abdillah Andi , Chalid Maisuri T. , Wicaksono Himawan , Ansyah A. Rusli Budi , Mudana I Nyoman
Published: February 2023

Sekitar 60%-80% kasus hipertiroidisme diakibatkan oleh Graves’ disease dimana wanita pada usia 20-50th lebih dominan dibandingkan laki-laki. Graves’ disease adalah suatu kelainan autoimun, adanya thyroid stimulating immunoglobulin (TSI), atau bisa disebut dengan thyroid stimulating antibody (TSAb) yang disekresikan di kelenjar tiroid berikatan dengan reseptor thyroid stimulating hormone (TSH) di kelenjar tiroid. Sehingga merangsang kelenjar tiroid untuk bekerja memproduksi hormon tiroksin berdasarkan rangsangan dari reseptor TSH. Rangsangan terus menerus dari TSAb mengakibatkan keadaan hipertiroidisme dan tiromegaly. Keadaan hipertiroidisme menyebabkan denyut jantung melemah dan gambaran pola EKG yang menunjukkan sindrom sinus sakit termasuk bradikardia sinus (denyut jantung <40 bpm), jeda sinus (jeda tiba-tiba nodus sinus lebih pendek dari 2-3 detik), dan henti sinus. Tujuan, Mengetahui karakteristik penderita gangguan kecemasan menyeluruh pada graves disease dengan gambaran EKG sick sinus syndrome (SSS). Metode, Penelitian ini merupakan Systematic Review dengan menggunakan metode Preferred Reporting Items for Systematic Reviews and Meta-analyses atau biasa disebut PRISMA, metode ini dilakukan secara sistematis dengan mengikuti tahapan atau protokol penelitian yang benar. Sumber diambil dari situs PubMed dan situs Google Scholar dengan jurnal terbitan tahun 2017-2022 lalu dilakukan screening didapatkan hasil 15.486. Hasil, Dilakukan klasterisasi jurnal dan didapatkan jumlah jurnal terindex scopus Q1 sejumlah 2 jurnal, Q2 2 jurnal, terindeks Sinta S1 1 jurnal, sehingga terdapat 5 jurnal yang diekstraksi. Kesimpulan, Mayoritas jurnal membahas mengenai usia dan gaya hidup yang berkaitan dengan karakteristik terjadinya grave disease serta faktor risiko grave disease ditentukan berdasarkan usia serta grave disease berhubungan dengan gangguan kecemasan, gambaran EKG sick sinus syndrome (SSS).
PERMBERDAYAAN POSYANDU REMAJA PADA KADER KESEHATAN DESA JATI KALANG PRAMBON SIDOARJO
Authors: Nurul Azizah  , Kusumawardani Paramtha Amelia , Rafhani Rosyidah  , Ratna Dwi Jayanti
Published: February 2023

Adolescence is a period of transition from children to adults, there are many changes experienced by adolescents, causing various kinds of problems, including reproductive health and psychology. The posyandu activities in Jati Kalang village, Prambon Sidoarjo didn’t run optimally.

The community service activities are aimed at optimizing youth posyandu activities. This activity was attended by 12 health cadres and 33 adolescent organizations. This activity starts with the formation of health cadres by involving cadres and youth in Jati Kalang village and joining by workshop and training.

The result of this activity indicates that the youth posyandu activities in Jati Kalang have been active again, through the formation of adolescent health cadres, and the holding of workshops and training health cadres on government programs related to youth posyandu, prevention of anemia, adolescent nutritional, adolescent reproductive health counselling and implementation five table system, as well as the delivery of medical equipment to support youth posyandu facilities. Youth posyandu activities held every 2 months at Jati Kalang village hall Prambon Sidoarjo.

Conclusion: The adolescent of Jati Kalang village were very enthusiastic to participate in the youth posyandu activities. The series of activities had run fluent and received a good response from the community.
PKM BUDIDAYA IKAN LELE (Clarias gariepinus) MENGGUNAKAN SISTEM BIOFLOK PADA GURU SMA SE-JAWA TIMUR
Authors: SWK Pungky , Andriani Vivin , Karunia Binawati Diah , Sukarjati  , Yachya Arif , Hariani Dyah , Amilah Susie
Published: February 2023

The Cultivation of high-density fish requires artificial feed with high protein content for growth. The higher the protein contained in the feed, the more expensive the feed price, while the feed is the largest cost reaching 60-70% of the production cost. In addition to the problem of feed in high-stocking density fish farming, of course, the waste disposal is also getting higher, which causes failure in the cultivation business. To overcome these problems, it is necessary to make a breakthrough in the cultivation system, one of which is catfish farming using a biofloc system by utilizing heterotrophic bacteria proven to reduce ammonia waste discharge in ponds. The results of this study need to be immediately socialized through training activities for high school teachers. The pretest and post-test results of trainees based on the percentage of activity objectives showed an increase with an average of 55%. It is hoped that the results of the training for high school biology teachers will not only get new knowledge about the application of biofloc to catfish farming. The knowledge gained can be disseminated to students in their schools to support better biology learning
PEMBUATAN LILIN AROMATERAPI DENGAN PEMANFAATAN LIMBAH MINYAK JELANTAH DI DESA KALANGANYAR
Authors: Fadilah Rizal Muhammad , Prisafitri Cindy Yuninda , Purwaningsih Dyan Wahyu , Baiti Zahwa Aisyah Nur , Diana Teresa Prisila , Lowa Edeltrudis , Sugijanto
Published: February 2023

Pengabdian warga yang dilaksanakan ini bertujuan untuk memberi pendampingan serta penyuluhan di desa Kalanganyar. Pengabdian dilaksanakan dengan mengaplikasikan sistem presentasi, pembicaraan interaktif, serta praktek langsung guna meningkatkan keahlian serta kreatifitas. Keinginan dari pendampingan yang sudah dikerjakan ini, warga tak hanya memiliki pengetahuan saja. tetapi juga pengetahuan luas selaku pengusaha kecil yang kreatif serta inovatif dalam pengolahan minyak goreng sisa ataupun minyak jelantah sebagai bahan baku pembuatan lilin aromaterapi. Pengabdian yang telah dilaksanakan bertujuan untuk  tingkatkan ekonomi, tetapi juga pemahaman akan kebersihan, kesehatan lingkungan serta bahayanya pelaksanaan minyak goreng secara berulang.
Stunting Prediction Model in Parepare City
Authors: Hengky Henni Kumaladewi , Rusman Ayu Dwi Putri
Published: February 2023

One of the big problems regarding nutrition in Indonesia is stunting. A condition known as stunting occurs when a person is shorter than other people. Stunting is caused by a number of things, including malnutrition, a lack of mothers' knowledge about nutrition, a lack of access to health services, a lack of nutritious food, and a lack of clean water and sanitation. The aim of this research was to predict model the incidence of stunting based on the risk factors for children. The cross-sectional design and observational analytical study method were utilized in this research. In the City of Parepare, there are 97 samples of children under the age of five. Interviews, questionnaires, and a length board were used to collect the data. The incidence of stunting was influenced by socioeconomic status (p-value=0,008) and immunization status (p-value=0,032), according to the Chi-square test. According to the results of the multivariate analysis, the most significant determinant of the prevalence of stunting in Parepare City was socioeconomic status.
Ferramentas e técnicas administrativas aplicadas para melhoria da qualidade do leite e redução de perdas econômicas numa Fazenda em Lajinha-MG
Authors: Dias de Oliveira Leonardo , Fernandes de Oliveira Altamir , Aparecida dos Santos Roseli , Santos Junior Hélio Sergio
Published: February 2023

Introdução: Um dos setores com maior problema nas propriedades leiteiras é o financeiro, devido alguns fatores como falta de planejamento e administração de recursos.  A mastite e em consequência a CCS elevada, reduzem em média 6% da produção de leite, além de trazer outros problemas como, descarte do leite, gasto e uso indiscriminado de medicamentos, serviço de profissionais e até perda por descarte ou morte dos animais.
Objetivos: Objetivou-se neste trabalho a utilização de ferramentas e técnicas da administração com intuito de criar um planejamento e atividades estratégicas que irão contribuir para redução da CCS do rebanho e consequentemente redução das perdas econômicas causadas pela CCS alta.
Métodos: Os dados foram obtidos da Fazenda Nossa Senhora das Graças, em Lajinha-MG. Por meio desses dados foi sugerido a utilização do Brainstorming, Diagrama de Pareto, Ciclo PDCA 5W2H, Programa 5S e Matriz SWOT, para realização de um programa de gestão eficiente da qualidade do leite.
Resultados: A mastite ocasionando aumento da CCS, resulta em perdas econômicas que o produtor não consegue visualizar sem ter uma avaliação dos índices referentes a esses elementos.  Faz-se necessário a utilização de ferramentas e técnicas para resolução de problemas em propriedades rurais destas como forma de melhorar o gerenciamento da propriedade e resolução de problemas relacionados a produção e gestão de recursos.
Conclusão: Conclui-se que é indispensável a presença de um profissional capacitado para acompanhar e interpretar os índices e resultados, usufruindo das ferramentas e técnicas para uma melhor gestão e redução de desperdícios, com objetivo de produzir com eficiência e tornar a propriedade rentável.
Análise de fatores de influência na criminalidade
Authors: Araujo Pena Stanley Araujo Pena
Published: February 2023

O Brasil é considerado um dos países mais violentos do mundo. Observando a relevância do tema e a ausência de pesquisas que apresentem uma revisão de literatura que identifique e aborde os principais fatores de interferência na criminalidade, propôs-se a realizar o estudo. Por meio da revisão integrativa de literatura, identificou-se 57 obras que apresentaram fatores capazes de interferir no fenômeno criminal. Estes elementos foram tratados e catalogados em cinco grupos Ao final, apresentaram-se sugestões para cinco fatores A pesquisa é classificada como descritiva, com emprego do método qualitativo e quantitativo, com consulta em fontes secundárias. A pesquisa contribui com as políticas de segurança pública, na medida em que identificou os principiais fatores que podem interferir no fenômeno criminal segundo pesquisas já realizadas.Palavras-chave: Controle. Segurança Pública. Criminalidade. Políticas Públicas.