bluuebunny/crossref_metadata_2025 huggingface dataset:
Enhancing Buoyant force learning through a visuo-haptic environment: a case study
Authors: Neri Luis , Noguez Julieta , Escobar-Castillejos David , Robledo-Rella Víctor , García-Castelán Rosa María Guadalupe , Gonzalez-Nucamendi Andres , Magana Alejandra J. , Benes Bedrich
Published: July 2024

Introduction: This study aimed to develop, implement, and test a visuo-haptic simulator designed to explore the buoyancy phenomenon for freshman engineering students enrolled in physics courses. The primary goal was to enhance students’ understanding of physical concepts through an immersive learning tool.

Methods: The visuo-haptic simulator was created using the VIS-HAPT methodology, which provides high-quality visualization and reduces development time. A total of 182 undergraduate students were randomly assigned to either an experimental group that used the simulator or a control group that received an equivalent learning experience in terms of duration and content. Data were collected through pre- and post-tests and an exit-perception questionnaire.

Results: Data analysis revealed that the experimental group achieved higher learning gains than the control group (p = 0.079). Additionally, students in the experimental group expressed strong enthusiasm for the simulator, noting its positive impact on their understanding of physical concepts. The VIS-HAPT methodology also reduced the average development time compared to similar visuo-haptic simulators.

Discussion: The results demonstrate the efficacy of the buoyancy visuo-haptic simulator in improving students’ learning experiences and validate the utility of the VIS-HAPT method for creating immersive educational tools in physics.
Contradictions in Chilean public education policy: physical education and health case
Authors: Reyes Rodríguez Alixon David , Martínez Rojas Ezequiel
Published: July 2024

The purpose of this text is to point out the contradiction existing in Chilean educational public policy regarding the curricular reform that converted the subjects of Physical Education and Health, History, Arts, and Religion into optional subjects for the 3rd and 4th years of high school. As far as Physical Education is concerned, scientific evidence shows that such conversion to the status of optional subject goes against the policies of other executive ministries and against the possibilities of reversing the statistics that show Chile as one of the countries in America with the highest percentage of overweight and obese children and adolescents.
Relationship of selected conditioning parameters and sport performance indicators in karate
Authors: Nema Kristina , Ruzbarsky Pavel , Rydzik Łukasz , Peric Tomas
Published: July 2024

Introduction

The variables of aerobic performance and aerobic capacity are of significant importance in maintaining intensity during a fight and also contribute to faster recovery between rounds in sports fighting in karate. Anaerobic performance is crucial for the execution of the techniques during high-intensity offensive or defensive actions that determine the outcome of a fight. The objective of this study was to assess the relationship between selected performance indicators of aerobic and anaerobic capacity to sports performance in karate.

Methods

The study included six male karate athletes (age 28 ± 3 years, body mass 85.10 kg; height 185.5 cm), medalists from European and World championship, events in senior categories. The selection criteria included training experience and sports level. The Karate specific aerobic test (KSAT) was use in conjunction with heart rate monitoring and changes in blood lactate levels to diagnose special aerobic endurance parameters. To determine the level of anaerobic performance the Wingate test were choosed. Technical and tactical indicators (efficiency, effectiveness and activeness of the attack) were used to assess the sports skill level during competition.

Results

Based on the Spearman correlation coefficient results demonstrated statistically significant differences (rs = −0.81) with large effect size index between efficiency of the attack and average heart rate achieved in the test KSAT. Additionally statistically significant differences (rs = 0.81) with large effect size were demonstrated between the fatigue index and efficiency of the attack Furthermore, the selected indicators of special aerobic endurance parameters and anaerobic performance demonstrated a high degree of predictive validity in relation to the efficiency (rp = 0.960) and activity (rp = 0.927) of attacks.

Conclusion

The high level of predictive validity confirmed the importance of a high level of anaerobic conditions for performance in karate. The low values of the average heart rate in relation to the efficiency of the attack confirm the high performance level of karate athletes in relation to special aerobic performance parameters. It was found that the effectiveness of the attack had no relation to the monitored parameters.
Efficacy of axillary dead space closure after mastectomy, axillary clearance and prosthetic reconstruction: a single-center preliminary experience
Authors: Lisa Andrea , Bozzo Giulia , Vinci Valeriano , Klinger Francesco Maria , Errico Valentina , Tinterri Corrado , Klinger Marco Ettore Attilio , Testori Alberto
Published: July 2024

Background

Postoperative seroma is most frequent after mastectomy (ME) in combination with axillary lymph node dissection (ALND), and its reported incidence varies from 15.5% up to 90%. Seromas can be responsible for discomfort, infections and can lead to reconstruction failure. Therefore, many ways of seroma prevention have been studied, although from a recent overview it has become clear that no single method is reliably successful. Mechanical closure of the dead space, however, was consistently found to be significantly effective. The aim of our study is to evaluate if quilting of the axilla, in patients undergoing ME, immediate prosthetic breast reconstruction and ALND reduces the duration of drain maintenance, the incidence of seromas that require aspiration (clinically significant seromas, CSS) and reconstruction failure rate.

Materials and methods

In our study population we analyzed a total of 81 patients divided into two groups: 27 consecutive patients undergoing mastectomy, axillary lymph node dissection (ALND), breast reconstruction and quilting of the axilla. We subsequently randomly picked up a double number of patients (54) undergoing the same oncological and reconstructive procedures without undergoing axillary quilting, matched for clinical characteristics in order to analyze efficacy of the procedure while reducing any bias. Our observational retrospective data was collected from October 2016 to July 2020 in one single high-volume center. Our median follow-up time was of 40.6 months.

Results

In the case group we observed a reduced time of drain maintenance: 16 vs. 20 days observed in the non-quilted group (p < 0.05). Incidence of seromas that required aspiration was 11% in the control group, while 3,7% in the case group. In addition to that, we observed 6 cases of implant removal in the control group, while in the quilted group we only observed a single case.

Conclusion

Previous literature and our results confirm that quilting of the axilla with flap fixation significantly decreases time of drain maintenance, allowing the earlier removal of the drains as well as decreasing the incidence of seroma, its eventual associated complications and related social costs. Moreover, our work suggests how quilting sutures decrease the incidence of seroma in patients undergoing immediate reconstruction, probably reducing the risk for implant removal.
In vitro impact of ethanolic extract of Bryonia laciniosa seed on Gir bull spermatozoa: a comprehensive evaluation through transcriptome profiling
Authors: Italiya Jignesh , Panchal Ketankumar J. , Jakhesara Subhash J. , Joshi Chaitanya G. , Koringa Prakash G.
Published: July 2024

Aim/objectives

This study examines the in vitro impact of an ethanolic extract derived from Bryonia laciniosa seeds on the Gir bull (Bos indicus) spermatozoa. The objective is to thoroughly assess the effects of the seed extract on the physiological parameters of bull spermatozoa, followed by evaluating its effects on X and Y-bearing spermatozoa and its impact on gene expression through transcriptome profiling.

Material method

For this study, one Gir bull was selected, and 12 ejaculates were collected at one-week time intervals. Sperm cells were isolated from each ejaculate and incubated with varying concentrations of the ethanolic extract. The physiological parameters of the spermatozoa were assessed using Computer Assisted Semen Analysis (CASA) and compared with control groups to evaluate the extract’s effects on sperm quality and motility.

Results and discussion

At a concentration of 18 mg/mL B. laciniosa extract, we noticed a statistically significant 16.4% increase in sperm motility (p = 0.0065). In order to understand the specific effect on X and Y-bearing spermatozoa, motile and non-motile sperm separated by glass wool column method and further evaluated for quantification of X and Y-bearing sperm in all samples by ddPCR. To understand the effect of B. laciniosa extract on spermatozoa at the molecular level, whole transcriptome profiling was carried out using Illumina MiSeq. Transcriptome profiling revealed 81 genes that were expressed differently between the group treated with the extract and the control group. The current investigation revealed an increase in the expression of TLX1, CRYGB, KLF13, and ZAR1 transcripts, which play a role in embryonic development. In addition, several genes have been identified that are involved in sperm motility, such GSK3B, LAPRS, MAPK1, CAMK2B, and AQP7. The findings exhibited the therapeutic effectiveness of B. laciniosa seeds in augmenting fertility through a synergistic blend of activities, including enhanced sperm motility and positive influence on embryogenesis.
Increasing Payload Capacity of a Continuum Soft Robot Using Bio-Inspired Ossicle Reinforcement
Authors: Garbulinski Jacek , Balasankula Sai C. , Wereley Norman M.
Published: July 2024

Soft continuum robots, characterized by their dexterous and compliant nature, often face limitations due to buckling under small loads. This study explores the enhancement of axial performance in soft robots intrinsically actuated with extensile fluidic artificial muscles (EFAMs) through the incorporation of bio-inspired radial supports, or ossicles. By conducting quasi-static force response experiments under varying pressure conditions (103.4–517.1 kPa), and a modified Euler column buckling model, we demonstrate that ossicles significantly increase the robots’ resistance to buckling, thereby extending their application scope in payload-carrying tasks. These findings not only underscore the effectiveness of ossicle reinforcement in improving structural robustness but also pave the way for future research to optimize soft robot design for enhanced performance.
Analysis of Agrometeorological Hazard Based on Knowledge Graph
Authors: Wu Di , Liu Xuemei , Zai Songmei , Zhang Liang , Feng Xuefang
Published: July 2024

Agrometeorological hazards significantly impact agricultural production and rural economic development. The interdisciplinary nature of studying these hazards poses challenges such as poor data interoperability in research. This paper proposes a method for analyzing agrometeorological hazards using knowledge graphs to understand occurrence patterns and devise response strategies. The study involves classifying agricultural and meteorological knowledge and designing a hazard entity model based on the characteristics and influencing factors of agrometeorological hazards. Data mining and extraction techniques are used to extract relevant information from multiple sources, and a knowledge graph for knowledge fusion and storage is built. The retrieval and inference capabilities of the knowledge graphs are used to intelligently analyze agrometeorological hazards. Results indicate that analyzing agrometeorological hazards using knowledge graphs is an innovative method that offers new perspectives and ideas for agricultural meteorological hazard research, thereby promoting the sustainable development of agricultural production and the stable growth of the rural economy.
Inconsistent Yield Response of Forage Sorghum to Tillage and Row Arrangement
Authors: Nieman Christine C. , Franco Jose G. , Raper Randy L.
Published: July 2024

Forage sorghum is an alternative source for biofuel feedstock production and may also provide forage for livestock operations. Introducing biofuel feedstock as a dual-use forage to livestock operations has the potential to increase the adoption of biofuel feedstock production. However, additional technical agronomic information focusing on tillage, row arrangement, and harvest date for forage sorghum planted into pasturelands intended for dual use is needed. Three tillage treatments, disking and rototilling (RT), chisel plow (CP), and no tillage (NT), and two row arrangement treatments, single-row planting with 76.2 cm rows and twin rows of 17.8 cm on 76.2 cm centers, were tested for effects on forage sorghum yield in a 3-cut system. This study tested two sites in Booneville, AR, from 2010 to 2012. Several interactions with year were detected, likely due to large precipitation differences within and among years. The year greatly affected the yield, with greater (p < 0.05) yields in year 1 compared to years 2 and 3 in both locations. No till resulted in lower yields in some years and harvest dates, though no clear trend was detected among tillage treatments over years. Twin rows generally did not improve yield, except for the third harvest date at one location. No strong trends for tillage or row arrangement effects were observed in this study. Inconsistencies may have resulted from the strong influence of year or interactions of multiple factors, which may challenge producers interested in utilizing forage sorghum for biofuels and livestock feed.
Modelling Fresh and Dry Weight of Aboveground Biomass of Plant Community and Taxonomic Group Using Normalized Difference Vegetation Index and Climate Data in Xizang’s Grasslands
Authors: Han Fusong , Ding Rang , Deng Yujie , Zha Xinjie , Fu Gang
Published: July 2024

In grassland ecosystems, aboveground biomass (AGB) is critical for energy flow, biodiversity maintenance, carbon storage, climate regulation, and livestock husbandry. Particularly on the climate-sensitive Tibetan Plateau, accurate AGB monitoring is crucial for assessing large-scale grassland livestock capacity. Previous studies focused on predicting AGB mainly at the plant community level and from the perspective of dry weight (AGBd). This study aims to predict grassland AGB in Xizang at both the plant taxonomic group (sedge, graminoid, forb) and community levels, from both an AGBd and a fresh weight (AGBf) perspective. Three to four independent variables (growing mean temperature, total precipitation, total radiation and NDVImax, maximum normalized difference vegetation index) were used for AGB prediction using nine models in Xizang grasslands. The random forest model (RFM) showed the greatest potential in simulating AGB (training R2 ≥ 0.62, validation R2 ≥ 0.87). This could be due to the nonlinear relationships between AGB, meteorological factors, and NDVImax. The RFM exhibited robustness against outliers and zero values resulting from taxonomic groups that were absent from the quadrats. The accuracies of the RFM were different between fresh and dry weight, and among the three taxonomic groups. The RFM’s use of fewer variables can reduce complexity and costs compared to previous studies. Therefore, the RFM emerged as the optimal model among the nine models, offering potential for large-scale investigations into grassland AGB, especially for analyzing spatiotemporal patterns of plant taxonomic groups.
Exploring the Relationship between Nitrogen Use Efficiency and Protein Concentrations in Potato Genotypes
Authors: Dimante Ilze , Skrabule Ilze , Sokolova Elina , Taskova Inese , Berga Dace , Sterna Vita
Published: July 2024

This two-year study assessed nitrogen use efficiency (NUE) and its effect on potato tuber protein concentration, focusing on crude protein concentration (CPC), crude protein yield (CPY), and patatin relative abundance (PRA) across 19 potato genotypes and four nitrogen management treatments (organic with no added fertilizers and three integrated treatments with N rates of 60, 120, and 180 kg ha−1). Nitrogen availability significantly affected CPC, with the highest average CPC across genotypes being 10.7% at 180 kg ha−1 and the lowest of 8.15% at 60 kg ha−1. Certain genotypes consistently outperformed others in terms of CPC and/or CPY under varying nitrogen treatments. A significant negative correlation was found between CPC and NUE, and genotypes with higher NUE typically had lower CPC. A positive correlation between CPY and NUE was observed, with the highest CPY of 1.36 t ha−1 at 120 kg N ha−1 in 2020. This suggests that higher NUE genotypes are more efficient in protein production per unit area. PRA varied significantly among genotypes, ranging from 8.7% to 35.51%. Although the relationship between NUE and PRA was weak, the significant and negative correlation indicates that cultivars with high NUE could have low PRA and vice versa. The findings underscore the importance of genotype variability in the relationship between NUE and protein content in potato tubers.
Correction: Chen et al. Bromelain Ameliorates Atherosclerosis by Activating the TFEB-Mediated Autophagy and Antioxidant Pathways. Antioxidants 2023, 12, 72
Authors: Chen Chia-Hui , Hsia Chien-Chung , Hu Po-An , Yeh Chung-Hsin , Chen Chun-Tang , Peng Cheng-Liang , Wang Chih-Hsien , Lee Tzong-Shyuan
Published: July 2024

In the original publication [...]
Vitis vinifera L. cv. Falanghina Seed Extracts: Antioxidant Effect of Bioactive Compounds on HepG2 Cells
Authors: Iervolino Stefania , Scarano Pierpaolo , Madera Jessica Raffaella , Franco Cristina , Tartaglia Maria , Stilo Romania , Sciarrillo Rosaria , Canzoniero Lorella Maria Teresa , Moreno Maria , Guarino Carmine
Published: July 2024

Vitis vinifera L. is a natural source of bioactive compounds that is already used for cosmeceutical and nutraceutical approaches. However, their phytochemical and antioxidant properties, although studied, have not been fully explored. We aimed to characterize V. vinifera L. cv. Falanghina seed extracts in different polarity solvents (hexane, ethyl acetate, ethanol, and a mixture of acetone–water) for their phytochemical contents, including the total phenolic compound content (TPC), free radical scavenging capacities, and antioxidant ability on HepG2 cells. We directly profiled the functional quality of V. vinifera seed extracts against H2O2-induced oxidative stress in HepG2 cells, focusing on mitochondrial functions. The content of bioactive compounds was characterized by LC-MS. To assess the cytocompatibility of the extracts, a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was conducted. Results showed that extraction with ethyl acetate (18.12 mg GAE·g−1) and ethanol solvents (18.07 mg GAE·g−1), through Soxhlet, and with an acetone–water mixture (14.17 mg GAE·g−1), through maceration, yielded extracts rich in (poly)phenols, with good scavenging and antioxidant activity (98.32 I% for ethanol solvents and 96.31 I% for acetone–water mixture). The antioxidant effect of polyphenols is at least partially due to their capacity to maintain mitochondrial biogenesis and mitophagy, which elevates mitochondrial efficiency, resulting in diminished ROS production, hence re-establishing the mitochondrial quality control. These findings highlight the valorization of Vitis by-products to improve food functional characteristics.
Deceptive Modulation of Actual and Perceived Effort While Walking Using Immersive Virtual Reality: A Teleoanticipatory Approach
Authors: Yamamoto Trent , Sahni Trinabh K. , McCabe Corinne A. , Nguyen Trevor L. , Blatney August E. , Lechner Ross J. , Nguyen Thalia H. , Benna Dominic M. , Farrales Jason P. , Mologne Mitchell S. , Neufeld Eric V. , Dolezal Brett A.
Published: July 2024

Virtual reality and technology-driven ‘exergaming’ have grown in tandem to expand the possibilities of exercise. However, few studies have investigated these aspects together in the context of treadmill walking. This study examined the effects of immersive virtual reality (IVR) on heart rate (HR) and ratings of perceived exertion (RPE) while walking on a treadmill at three different speeds, only one of which was disclosed to participants. Using a single-blinded, randomized control trial with a crossover research design, sixteen college-aged adults (eight females, mean age of 20.5 ± 1.2 years) were randomly assigned a testing order for six trials of treadmill walking. Three 10 min trials were conducted with IVR and three were conducted without on two separate days; a 3 min break was given in between trials. Borg RPE scores were assessed after each trial, while HR was monitored throughout. The IVR trials produced lower mean RPE scores in comparison to the non-IVR group at 3.5 and 3.7 mph. The IVR trials also yielded a lower mean HR compared to the non-IVR trials at the highest speed of 3.7 mph. These findings suggest that IVR may be able to attenuate RPE scores and HR while walking on a treadmill.
Assessment of Production Technologies on Dairy Farms in Terms of Animal Welfare
Authors: Gaworski Marek , Kic Pavel
Published: July 2024

Dairy production on farms is based on properly selected technologies implemented in various areas of the barn and outside the livestock buildings. These technologies are subject to assessment, for example, to determine the possibilities of their further improvement in the given production conditions of the farm. When assessing dairy production technology on a farm, human interests are taken into account, including workload, time and access to modern tools supporting the control of production processes. The aim of this review is to identify and discuss factors in dairy production technologies that may affect the welfare of dairy cattle. The considerations indicate that in the technologies of cow feeding, watering and housing, the priority is to improve the technology in terms of ensuring the comfort of animals using feed, water and a place to rest. However, in the case of the assessment of milking automation, the key importance of increasing human comfort was indicated, taking into account the comfort of cows, which is an additional factor justifying the implementation of technical progress in milking. The assessment of various dairy production technologies on farms is an excellent opportunity to develop discussions on the place of dairy cattle welfare in the sustainable development of farms and the priorities set for improving dairy production.
Optimizing the Performance of Window Frames: A Comprehensive Review of Materials in China
Authors: Wang Zhen , Yao Lihong , Shi Yongguang , Zhao Dongxia , Chen Tianyu
Published: July 2024

As the construction industry places increasing emphasis on environmental conservation and sustainability, this trend has spurred profound research into the optimization of door and window performance. One of the critical components of windows is their frames. Over the past several decades, the design of window frames has undergone significant innovations, ranging from introducing new materials to novel design concepts. The performance of window frames is typically influenced by materials, structural design, and the surrounding environment. Consequently, this paper analyzes the common window frame materials in Chinese civil buildings through investigation. It explores commonly used types of window frames available in the market, focusing on their materials and structural designs. It analyzes issues observed during their usage, integrates findings from existing research, and discusses the performance of window frame materials. Additionally, it explores improvement strategies to meet the evolving demands of contemporary and future architectural doors and windows, providing valuable reference points for designers. Finally, approaching the discussion from a sustainable development perspective, the paper evaluates the environmental impact of wood, aluminum alloy, polymer, and composite window frame materials. It emphasizes that wood- and aluminum-clad wood windows represent sustainable options with versatile applications in diverse scenarios.
Structure and Optoelectronic Properties of Perovskite-like (PEA)2PbBr3Cl on AlN/Sapphire Substrate Heterostructure
Authors: Lin Yu-Hsien , Ni Jing-Suei , Chen Lung-Chien
Published: July 2024

This study presents the structure and optoelectronic properties of a perovskite-like (PEA)2PbBr3Cl material on an AlN/sapphire substrate heterostructure prepared using spin coating. The AlN/sapphire substrate comprised a 2 μm thick AlN epilayer on a sapphire wafer deposited via metal–organic chemical vapor deposition (MOCVD). The peak position of (PEA)2PbBr3Cl photoluminescence (PL) on the AlN/sapphire substrate heterostructure was 372 nm. The emission wavelength ranges of traditional lead halide perovskite light-emitting diodes are typically 410 to 780 nm, corresponding to the range of purple to deep red as the ratio of halide in the perovskite material changes. This indicates the potential for application as a UV perovskite light-emitting diode. In this study, we investigated the contact characteristics between Ag metal and the (PEA)2PbBr3Cl layer on an AlN/sapphire substrate heterostructure, which improved after annealing in an air environment due to the tunneling effect of the thermionic-field emission (TFE) mechanism.
The Compositional and Functional Diversity of a Mediterranean Urban Lake’s Fish Fauna over the Past 120 Years
Authors: Petriki Olga , Bobori Dimitra C.
Published: July 2024

This study examines the compositional (taxonomic) and functional diversity changes in the fish fauna of a Mediterranean urban lake (Lake Kastoria) over a period of 12 decades (1900–2020, as of 2022). Moreover, the current status (2010 and 2022) of the fish fauna is assessed along with the lake’s ecological quality. Intentional or accidental species introductions resulted in significant compositional changes in the lake’s fish fauna. The functional richness among the assemblages from 1900 and 2020 was increased due to species introductions, resulting in a peak of functional dissimilarity in 1990, when most introductions took place. However, the functional dissimilarity measures revealed that there have been moderate changes in groups of the functional traits which may be indicative of high species competition. The lake’s open waters are dominated by Rutilus rutilus and the introduced species Perca fluviatilis and Lepomis gibbosus. The estimated ecological quality was higher in 2022 than in 2010, categorizing the lake as having “Moderate” quality and providing an upgrade from its earlier ‘Poor” condition. This positive shift is attributed in part to the burgeoning population of Perca fluviatilis, as evidenced by increased catch rates. The species’ resurgence may be linked to enhancements in the lake’s physicochemical parameters, potentially facilitated by more effective treatment of urban wastes. The study underscores the complex interplay between species introductions, functional diversity, and ecological quality in the urban Lake Kastoria, highlighting the need for continued monitoring and management efforts to sustainably preserve and enhance the biodiversity and ecological integrity of urban aquatic ecosystems.
NOx Formation Mechanism and Emission Prediction in Turbulent Combustion: A Review
Authors: Wang Zhichao , Yang Xiaoyi
Published: July 2024

The field of nitric oxide (NOx) production combined with turbulent flow is a complex issue of combustion, especially for the different time scales of reactions and flow in numerical simulations. Around this, a series of approach methods, including the empirical formula approach, the computational fluid dynamics (CFD) approach coupling with an infinite rate chemical reaction, the chemical reaction networks (CRNs), and the CFD approach coupling with CRNs, were classified, and we discussed its advantages and applicability. The empirical-formula approach can provide an average range of NOx concentration, and this method can be involved only in special scenarios. However, its simplicity and feasibility still promote practical use, and it is still widely applied in engineering. Moreover, with the help of artificial intelligence, this method was improved in regard to its accuracy. The CFD approach could describe the flow field comprehensively. In compliance with considering NOx formation as finite-rate chemical reactions, the NOx concentration distribution via simulation cannot match well with experimental results due to the restriction caused by the simplification of the combustion reaction. Considering NOx formation as a finite-rate chemical reaction, the CRNs approach was involved in CFD simulation, and the CRNs approach could forecast the NOx concentration distribution in the flow field. This article mainly focuses on the simulation method of nitric oxide (NOx) production in different combustion conditions. This review could help readers understand the details of the NOx formation mechanism and NOx formation prediction approach.
Low-Overlap Bullet Point Cloud Registration Algorithm Based on Line Feature Detection
Authors: Zhang Qiwen , Mu Zhiya , He Xin , Wei Zhonghui , Hao Ruidong , Liao Yi , Wang Hongyang
Published: July 2024

A bullet point cloud registration algorithm with a low overlap rate based on line feature detection was proposed to solve the problem of the difficulty and low efficiency of point cloud registration due to the low overlap rate among point clouds sampled by the bullet model. In this paper, voxel downsampling is used to remove some noise points and outliers from the bullet point cloud and applied to the specified resolution to reduce the calculation cost. The bullet point cloud is transformed to a better initial position by fitting the central axis with the geometrical features of the bullet. Then, the direction vector of the bullet linear features is obtained by using an icosahedral fitting discrete Hough transform to simplify the parameter space of the search transformation. Finally, the optimal rotation angle is searched for in the parameter space by using the improved Cuckoo algorithm to realize the registration of the bullet point cloud with a low overlap rate. Simulation and experimental results show that the proposed registration method can accurately register bullet point clouds of different densities with a low overlap rate. Compared with the commonly used ICP, GICP, and TRICP algorithms, the registration error of the proposed algorithm is reduced by 92.68% on average when the overlap rate is 52.85%. The registration error is reduced by 98.87% in the case of a 41.36% overlap rate, by 99.52% in the case of a 33.02% overlap rate, and by 98.89% in the case of a 22.75% overlap rate.
Factors Affecting Water Deprivation Resistance in Bactrocera oleae (Olive Fruit Fly)
Authors: Balampekou Evangelia I. , Koveos Dimitrios S. , Koutsos Thomas M. , Menexes Georgios C. , Kouloussis Nikos A.
Published: July 2024

The olive fruit fly, Bactrocera oleae (Rossi) (Diptera: Tephritidae), causes significant damage to olive crops worldwide. However, the factors affecting its survival under water deprivation have not been studied yet. In this study, the water deprivation resistance of male and female olive fruit flies was measured at three ages in virgin and mated adults fed either a full or a restricted diet. The experiments (24 treatments) were conducted under constant laboratory conditions, using insects collected in the wild and reared on olives. Additionally, a baseline experiment was conducted to provide data on the insects’ life expectancy under no-stress conditions. Our findings revealed that males showed much less resistance under water deprivation compared to females. Younger adults endured for longer than older ones, and adults fed a restricted diet endured water deprivation longer than those fed a full diet. Our results suggest that during periods of water scarcity, releasing sterile males is most effective, because the wild male population decreases. Since females of reproductive age are more resistant, this should ensure a higher number of matings with sterile males. These findings can be used to formulate improved pest control strategies that enhance olive product quality while relying less on insecticides.
Generalized Fuzzy-Valued Convexity with Ostrowski’s, and Hermite-Hadamard Type Inequalities over Inclusion Relations and Their Applications
Authors: Cortez Miguel Vivas , Althobaiti Ali , Aljohani Abdulrahman F. , Althobaiti Saad
Published: July 2024

Convex inequalities and fuzzy-valued calculus converge to form a comprehensive mathematical framework that can be employed to understand and analyze a broad spectrum of issues. This paper utilizes fuzzy Aumman’s integrals to establish integral inequalities of Hermite-Hahadard, Fejér, and Pachpatte types within up and down (U·D) relations and over newly defined class U·D-ħ-Godunova–Levin convex fuzzy-number mappings. To demonstrate the unique properties of U·D-relations, recent findings have been developed using fuzzy Aumman’s, as well as various other fuzzy partial order relations that have notable deficiencies outlined in the literature. Several compelling examples were constructed to validate the derived results, and multiple notes were provided to illustrate, depending on the configuration, that this type of integral operator generalizes several previously documented conclusions. This endeavor can potentially advance mathematical theory, computational techniques, and applications across various fields.
Can Hyaluronic Acid Combined with Chondroitin Sulfate in Viscosupplementation of Knee Osteoarthritis Improve Pain Symptoms and Mobility?
Authors: Dima Augustin , Dragosloveanu Magda , Romila Andreea Ramona , Cristea Alexandru , Marinică Georgiana , Dănilă Alexandru-Tiberiu , Mandici Alexandru , Cojocariu Daniel , Vlad Robert-Alexandru , Ciurba Adriana , Bîrsan Magdalena
Published: July 2024

The objective of the present study was to assess the effect of intra-articular Hyaluronic acid (HA) and Chondroitin sulfate (CS) supplementation (Hialurom® Hondro (HH)) on pain symptoms and joint mobility. In total, 60 mg/mL sodium hyaluronate and 90 mg/mL CS were administered to 21 patients (17 females and 4 males) respecting the in-force requirements, excluding patients with some specific comorbidities. In addition to the clinical study (where the pain intensity (severity) and joint mobility were assessed), rheological characterization was conducted evaluating the following parameters: elastic modulus (G′), loss modulus (G″) oscillatory frequency (fc) at 0.5 Hz and 2.5 Hz, crossover frequency (fc), relaxation time (λ) where it was noticed that the addition of chondroitin sulfate (CS) to sodium hyaluronate (SH) significantly enhances and improves the viscoelastic properties, particularly at higher shear frequencies. A significant decrease in pain intensity felt by the subjects was found, from 7.48 (according to Wong–Baker scale)—pain close to 8 (the patient is unable to perform most activities), to more reduced values of 5.86—at 6 weeks after injection, 4.81—at 3 months after injection, and 5.24—at 6 months after injection, improvements in symptoms was fast and durable. Data related to the evolution of joint mobility show that at 6 weeks after injection, the mobility of joints increased by 17.8% and at 6 months by 35.61%. No serious adverse events were reported with undesired effects so that they would impose additional measures. Better resistance to enzymatic degradation and free radicals could be expected from the synergic combination of sodium hyaluronate and chondroitin sodium sulfate, this having a special importance for the patients, granting them the ability to perform more ample movements and reducing dependency on attendants, thus increasing quality of life.
Reversible Histone Modifications Contribute to the Frozen and Thawed Recovery States of Wood Frog Brains
Authors: Bloskie Tighe , Taiwo Olawale O. , Storey Kenneth B.
Published: July 2024

Epigenetic regulation, notably histone post-translational modification (PTM), has emerged as a major transcriptional control of gene expression during cellular stress adaptation. In the present study, we use an acid extraction method to isolate total histone protein and investigate dynamic changes in 23 well-characterized histone methylations/acetylations in the brains of wood frogs subject to 24-h freezing and subsequent 8-h thawed recovery conditions. Our results identify four histone PTMs (H2BK5ac, H3K14ac, H3K4me3, H3K9me2) and three histone proteins (H1.0, H2B, H4) that were significantly (p < 0.05) responsive to freeze-thaw in freeze-tolerant R. sylvatica brains. Two other permissive modifications (H3R8me2a, H3K9ac) also trended downwards following freezing stress. Together, these data are strongly supportive of the proposed global transcriptional states of hypometabolic freeze tolerance and rebounded thawed recovery. Our findings shed light on the intricate interplay between epigenetic regulation, gene transcription and energy metabolism in wood frogs’ adaptive response to freezing stress.
Bile Acids as Emerging Players at the Intersection of Steatotic Liver Disease and Cardiovascular Diseases
Authors: Bilson Josh , Scorletti Eleonora , Swann Jonathan R. , Byrne Christopher D.
Published: July 2024

Affecting approximately 25% of the global population, steatotic liver disease (SLD) poses a significant health concern. SLD ranges from simple steatosis to metabolic dysfunction-associated steatohepatitis and fibrosis with a risk of severe liver complications such as cirrhosis and hepatocellular carcinoma. SLD is associated with obesity, atherogenic dyslipidaemia, and insulin resistance, increasing cardiovascular risks. As such, identifying SLD is vital for cardiovascular disease (CVD) prevention and treatment. Bile acids (BAs) have critical roles in lipid digestion and are signalling molecules regulating glucose and lipid metabolism and influencing gut microbiota balance. BAs have been identified as critical mediators in cardiovascular health, influencing vascular tone, cholesterol homeostasis, and inflammatory responses. The cardio-protective or harmful effects of BAs depend on their concentration and composition in circulation. The effects of certain BAs occur through the activation of a group of receptors, which reduce atherosclerosis and modulate cardiac functions. Thus, manipulating BA receptors could offer new avenues for treating not only liver diseases but also CVDs linked to metabolic dysfunctions. In conclusion, this review discusses the intricate interplay between BAs, metabolic pathways, and hepatic and extrahepatic diseases. We also highlight the necessity for further research to improve our understanding of how modifying BA characteristics affects or ameliorates disease.
Assessing Lymph Node Involvement in Muscle-Invasive Bladder Cancer: Proposal of a Predictive Model Using Clinical Variables
Authors: Barragán Flores William A. , Carrillo George Carlos , Sandoval José María , Cívico Sánchez Claudia , Flores Cristina , Muñoz Victoria , Fernández Aparicio Tomás
Published: July 2024

Background: Lymph node involvement (N+) in bladder cancer indicates a poor prognosis. Current preoperative evaluations of N+ are often inaccurate. We aimed to develop a predictive model for N+ using basic clinical variables and assess the diagnostic accuracy of Computed Tomography (CT). Methods: A retrospective cohort study was conducted. We include 62 MIBC patients who underwent radical cystectomy (RC) from 2010 to 2019 in our center. We evaluated diagnostic concordance between CT and histopathology for extravesical extension (T3a≥) and N+. Univariate and multivariate logistic regressions were used to create a predictive model, with an ROC curve and nomogram developed. Results: We found 59% sensitivity and 69% specificity for CT for staging cT3≥ and a sensitivity of 22% and a specificity of 21% for N+. NLR > 2.60 (OR 6.03, p = 0.02) and lymphovascular invasion (LVInv) in the TURB sample (OR 9.26, p = 0.04) were correlated with N+. Both fundus lesions (OR 0.21, p = 0.04) and creatinine > 0.94 mg/dL (OR 0.17, p = 0.025) were associated with reduced risk. The ROC curve of the model showed 80.4% AUC. Conclusions: A predictive model with good diagnostic performance for N+ can be developed from basic clinical data. CT sensitivity and specificity for the detection of N+ patients are limited.
Epidemic, Urban Planning and Health Impact Assessment: A Linking and Analyzing Framework
Authors: Jiang Xiji , Ye Dan , Lan Wenlong , Luo Yinglu
Published: July 2024

The occurrence and spread of infectious diseases pose considerable challenges to public health. While the relationship between the built environment and the spread of infectious diseases is well-documented, there is a dearth of urban planning tools specifically designed for conducting Health Impact Assessments (HIAs) targeted at infectious diseases. To bridge this gap, this paper develops a comprehensive framework of an HIA for Urban Planning and Epidemic (HIA4UPE), formulated by considering the progression of public health incidents and the distinct transmission patterns of infectious diseases. This framework is designed to provide a comprehensive assessment by including a health risk-overlay assessment, health resource-quality assessment, health resource-equality assessment, and health outcome-impact prediction, enabling a multidimensional evaluation of the potential impacts of current environmental conditions or planning proposals on the incidence of infectious diseases. Furthermore, this paper advances the application of spatial analysis and computation, comprehensive assessment methodologies, and predictive analytics to conduct specific assessments. The theoretical framework and analytical tools presented in this paper contribute to the academic discourse and offer practical utility in urban planning and policymaking on epidemic prevention and control.
Operability, Multiscalarity, Diversity, and Complexity in the UNESCO Heritage Regulatory Framework
Authors: Rodríguez-Segura Adrián , Loren-Méndez Mar , Galán-Conde José María
Published: July 2024

The historical genealogy of the heritage regulatory framework, spanning from the 20th century to the present day, provides insights into the continuous socio-cultural transformations within communities. It also sheds light on the successive expansions and reformulations that have shaped the understanding of the heritage phenomenon up to its current conception. This research presents a historical methodology that traces the Charters and Conventions within the UNESCO domain by creating a matrix of cross-cutting vectors that span the heritage phenomenon. Through this matrix, it becomes possible to unveil and pinpoint the emergence, changes, and sociocultural mutations identified within the UNESCO normative framework. The present research not only identifies the emergence of these vectors but also delves into their facets and nuances, relationships, and interactions. The study unfolds in three phases: during the initial phase, the four main vectors in understanding the heritage phenomenon (Operability, Multiscalarity, Diversity, and Complexity) are identified, encompassing their origin, emergence, nuances, and facets. In the second phase, the evolution, scope, and permanence of each vector are closely monitored across its different facets. Finally, the crossovers between them are analyzed, revealing their relationships, interactions, and thus mutual influence.
An Experimental and Numerical Parametric Study on a Novel T-Shaped Steel–Concrete Composite Shear Wall
Authors: Mo Xuan , Yuan Zhijun , Jia Yigang , Lu Liangjian , Wei Xianglan , Ke Naiwen
Published: July 2024

In this paper, a novel T-shaped steel–concrete composite shear wall (TSCCW) is proposed. Low-cycle reciprocating tests were carried out on the TSCCW to investigate its performance in terms of its damage characteristics, hysteretic properties, energy dissipation capacity, stiffness degradation and ductility. A numerical model was established on the basis of the tests, and the correctness of the numerical model was verified. Afterwards, parameters such as shear span ratio, axial load ratio, rebar diameter, steel thickness, concrete strength grade and axial compression position were analyzed. The results show that the shear span ratio has a great influence on the performance of the TSCCW. A reduction in the shear span ratio from 2.1 to 1 reduces its stiffness by 333%. An increase in the axial load ratio will increase the load carrying capacity and stiffness of the TSCCW, and the deformation capacity will first increase and then decrease; it is recommended that the axial load ratio should be taken as 0.4. Increasing the steel thickness will improve the load carrying capacity, stiffness, deformation capacity and energy dissipation capacity of the TSCCW to a certain extent. Increasing the reinforcement diameter has less effect on the seismic performance of the TSCCW.
Numerical Parameter Analysis of High-Strength Steel Frame with Y-Eccentric Brace Using Variable Replaceable Link
Authors: Chen Xi , Li Shen , Liang Gang , He Min
Published: July 2024

The present study proposes a variable replaceable link for high-strength steel frames with Y-eccentric braces designed to effectively dissipate earthquake energy by confining plastic deformation to its central zone. This unique feature allows for easy post-earthquake recovery or replacement. To investigate the seismic performance of such structures, a comprehensive finite element numerical parametric analysis is conducted using ABAQUS software. Various parameters, including the length of the central zone, replaceable link length, span, and steel grade are considered to optimize the structural design. This study examines the failure modes, hysteretic behavior, bearing capacity, plastic rotation of the replaceable link, and ductility of structures under cyclic loading. The results indicate that reducing the span and utilizing high-strength steel significantly enhance the ductility and ultimate bearing capacity of the structure. This approach also reduces the cross-sectional dimensions, saves steel material, and limits the development area of plasticity, thereby facilitating post-earthquake repair of links after rare earthquakes. An optimal length of the link improves the structural stiffness and energy dissipation capacity. However, if it is too short or too long, it complicates post-earthquake repairs and impairs energy dissipation performance. The conclusions drawn from this research aim to provide valuable insights and theoretical foundations for future structural designs.