bluuebunny/crossref_metadata_2025 huggingface dataset:
The Fungal EndophyteEpichloë festucaevar.loliiDoes Not Improve the Freezing Tolerance of Perennial Ryegrass
Authors: Heineck Garett C. , Watkins Eric , Ehlke Nancy Jo
Published: June 2018

A lack of winter hardiness limits the utility of perennial ryegrass (Lolium perenneL.) as a turf and forage grass in northern latitudes. The fungal endophyteEpichloë festucaevar.loliiis commonly associated with perennial ryegrass and is believed to enhance stress tolerance in some environments. The effect ofE. festucaevar.loliion freezing tolerance was assessed using seven diverse perennial ryegrass entries. Freezing tolerance was used as a proxy for winter hardiness, and most entries had been previously field tested to confirm this supposition. Three experiments were designed to isolate the effect of the endophyte from confounding effects from the grass host and the endophyte removal process. Experiment 1 compared hosts with (E+) or without (E−) endophytes that were either genetically identical or non‐isogenic, but from the same entry. Isogenic E+ and E− plants did not differ in freezing tolerance; however, some non‐isogenic populations differed in freezing tolerance. Experiment 2 used additional populations of non‐isogenic hosts to confirm the association between freezing tolerant hosts and endophyte infection. Isogenic hosts were polycrossed and the half‐sib E+ and E− progeny were used in Exp. 3, eliminating any effect of the endophyte removal process. Freezing tolerance did not vary between related families differing in endophyte infection, confirming that highly related hosts were not affected by endophyte. These results strongly suggest that nativeE. festucaevar.loliihas no direct effect on freezing tolerance but may be found in higher frequencies in freezing‐tolerant hosts.
Effect of using different proportions of inoculum during bioleaching on sludge dewaterability
Authors: Zhang Qingfang , Yang Wenfeng , Yang Qiyong , Wang Tianfeng , Chen Shenliang , Zou Moliang , Yang Zengye
Published: June 2018

Bioleaching, the addition of bacteria to geological materials, has been applied to sludge to remove metals and improve upon sludge dewaterability. This paper investigates the effect of using different quantities of inoculum (bacteria) during bioleaching on sludge dewaterability. The analysis was based on bioleaching experiments conducted in a 20 L bio-reactor using different quantities of inoculum (20%, 10%, 5%, 2%, 0%). Changes in pH, oxidation reduction potential (ORP), capillary suction time (CST), specific resistance to filtration (SRF) and extracellular polymeric substances (EPS) were determined to gauge sludge dewatering. Results indicate that sludge dewaterability during the 2%, 10%, and 20% inoculum experiments declined through time. Decreased dewaterability is attributed to increases in the quantity of proteins and polysaccharides in slime EPS. Dewaterability improved during the 5% inoculum experiment, and reached a maximum when pH was 2.3. During this latter experiment, CST and SRF were reduced by 74% and 62%, respectively, in comparison to control conditions, while total EPS content decreased by 71%. The decrease in total EPS was primarily due to a decrease in proteins associated with tightly bound EPS (TB-EPS). Thus, changes in the amount of proteins in TB-EPS and sludge pH played a crucial role in sludge dewaterability.
Variables transdiagnósticas predictoras de los problemas emocionales y afectivos en una muestra colombiana
Authors: Toro Tobar Ronald Alberto , Beltrán Aguirre Kerly Vanessa , González Gómez Laura Jimena , Sabogal Mancipe Ángela Paola , Reyes Parra Karolina , Guerrero Ortiz Luz Mery
Published: June 2018

El modelo transdiagnóstico se basa en la evaluación y tratamiento de las variables etiológicas y mantenedoras de los trastornos mentales. El objetivo fue establecer la relación entre las variables transdiagnósticas perfeccionismo, rumiación, afecto positivo y negativo, sensitividad ansiosa e intolerancia a la incertidumbre, con estrés, ansiedad y depresión. Participaron 333 adultos convocados mediante muestreo no probabilístico incidental, cuyas edades oscilaron entre los 18 y los 70 años (M = 28, DE = 8,70), un 37,46% hombres y un 62,54% mujeres, solteros (66,27%), universitarios (65,57%) principalmente. Se llevó a cabo un estudio no experimental predictivo transversal. En los resultados se encontraron correlaciones significativas entre ansiedad y depresión, además de intolerancia a la incertidumbre y perfeccionismo, y depresión con afecto positivo-negativo y perfeccionismo. En estrés se obtuvieron correlaciones significativas con rumiación y estilo emocional. El modelo predictivo resaltó las variables intolerancia a la incertidumbre, sensitividad ansiosa y afecto positivo y negativo para predecir ansiedad (r2 = 0,43), depresión (r2 = 0,37) y estrés (r2 = 0,17). Se concluyó que los resultados aportan evidencias a favor del modelo transdiagnóstico para la ansiedad y depresión y en menor medida para estrés.
The Promising Role of Plant Tannins as Bioactive Antidiabetic Agents
Authors: Ajebli Mohammed , Eddouks Mohamed
Published: June 2018

Background:

Plant tannins are polyphenolic substances with various molecular weights and a variable complexity. Due to the beneficial effects for controlling chronic disorders particularly diabetes mellitus, this class of secondary metabolites has gained more interest in the recent years.

Objective:

We aimed through this review to collect, analyze and discuss all available information related to the antidiabetic effect of isolated tannins (including both condensed and hydrolysable varieties) and tannin-rich plants as well as the possible mechanisms of action involved in this antidiabetic activity.

Methods and Results:

Our bibliographic research was conducted to gather more than 41 medicinal plants containing tannins and 19 isolated tannins and tannin-rich crud extracts which were revealed to possess glucose lowering effect according to pharmacological studies.

Conclusion:

Hence, according to findings of the present review, tannins could be useful for prevention and management of diabetes mellitus and its associated complications and these natural products could be promising compounds for the discovery of new hypoglycemic agents.
Phytosterols in Cancer: From Molecular Mechanisms to Preventive and Therapeutic Potentials
Authors: Blanco-Vaca Francisco , Cedó Lídia , Julve Josep
Published: June 2018

Cancer is the second leading cause of death worldwide. Compelling evidence supports the hypothesis that the manipulation of dietary components, including plant compounds termed as phytochemicals, demonstrates certain important health benefits in humans, including those in cancer. In fact, beyond their well-known cardiovascular applications, phytosterols may also possess anticancer properties, as has been demonstrated by several studies. Although the mechanism of action by which phytosterols (and derivatives) may prevent cancer development is still under investigation, data from multiple experimental studies support the hypothesis that they may modulate proliferation and apoptosis of tumor cells. Phytosterols are generally considered safe for human consumption and may also be added to a broad spectrum of food matrices; further, they could be used in primary and secondary prevention. However, few interventional studies have evaluated the relationship between the efficacy of different types and forms of phytosterols in cancer prevention. In this context, the purpose of this review was to revisit and update the current knowledge on the molecular mechanisms involved in the anticancer action of phytosterols and their potential in cancer prevention or treatment.
Assessing and Grouping Chemicals Applying Partial Ordering Alkyl Anilines as an Illustrative Example
Authors: Carlsen Lars , Bruggemann Rainer
Published: June 2018

Aim and Objective:

In chemistry, there is a long tradition in classification. Usually,
methods are adopted from the wide field of cluster analysis. The present study focusses on the
application of partial ordering methodology for the classification of 21 alkyl substituted anilines.

Materials and Methods:

The analyses are based on the concepts from partial order methodology and
cluster analyses. Here, with the example of 21 alkyl anilines, we show that concepts taken out from
the mathematical discipline of partially ordered sets may be applied for classification. The chemical
compounds are described by a multi-indicator system. For the present study four indicators, mainly
taken from the field of environmental chemistry were applied and a graph of the ordering (Hasse
diagram) was constructed.

Results:

A Hasse diagram is an acyclic, transitively reduced, triangle-free graph that may have
several graph-theoretical components. The Hasse diagram has been directed from a structural
chemical point of view. Two cluster analysis methods are applied (K-means and a hierarchical
cluster method) and compared with the results from the Hasse diagram. In both cases, the
partitioning of the set of 21 compounds by the component structure of the Hasse diagram appears to
be better interpretable.

Conclusion:

It is shown that the partial ordering approach indeed can be used for classification in the
present case. However, it must be clearly stated that a guarantee for meaningful results, in general,
cannot be given. For that, further theoretical work is needed.
Atom-based and Pharmacophore-based 3D – QSAR Studies on Vitamin D Receptor (VDR)
Authors: Nagamani Selvaraman , Kesavan Chandrasekhar , Muthusamy Karthikeyan
Published: June 2018

Aim and Objective:

Vitamin D3 (1,25(OH)2D3) is a biologically active metabolite and
plays a wide variety of regulatory functions in human systems. Currently, several Vitamin D
analogues have been synthesized and tested against VDR (Vitamin D Receptor). Electrostatic
potential methods are greatly influence the structure-based drug discovery. In this study, ab inito
(DFT, HF, LMP2) and semi-empirical (RM1, AM1, PM3, MNDO, MNDO/d) charges were
examined on the basis of their concert in predicting the docking pose using Induced Fit Docking
(IFD) and binding free energy calculations against the VDR.

Materials and Methods:

Initially, we applied ab initio and semi-empirical charges to the 38 vitamin
D analogues. Further, the charged analogues have been docked in the VDR active site. We generated
the structure-based 3D-QSAR from the docked conformation of vitamin D analogues. On the other
hand, we performed pharmacophore-based 3D-QSAR.

Results:

The result shows that, AM1 is the good charge model for our study and AM1 charge based
QSAR produced more accurate ligand poses. Furthermore, the hydroxyl group in the side chain of
vitamin D analogues played an important role in the VDR antagonistic activity.

Conclusion:

Overall, we found that charge-based optimizations of ligands were out performed than
the pharmacophore based QSAR model.
Synthesis and Anticancer Activity of Some 1H-inden-1-one Substituted (Heteroaryl)Acetamide Derivatives
Authors: Karaburun Ahmet Cagri , Gundogdu-Karaburun Nalan , Yurttas Leyla , Kayagil Ismail , Demirayak Seref
Published: June 2018

Background:

The synthesis of 2-[3/4-((6-substituted-1-oxo-2,3-dihydro-1H-inden-2-
ylidene)methyl)phenoxy]-N-(heteroaryl)acetamide derivatives and the investigation of their anticancer
activity were studied.

Methods:

2-(3/4-Hydroxybenzylidene)-6-substituted-2,3-dihydro-1H-inden-1-ones were reacted with
suitable 2-chloroacetamides to give 2-[3/4-((6-substituted-1-oxo-2,3-dihydro-1H-inden-2-ylidene)
methyl)phenoxy]-N-(heteroaryl)acetamide derivatives.

Results:

The structure elucidation of the newly synthesised 16 compounds was performed by IR,
1H-NMR, mass spectroscopic data and elemental analyses. The anticancer screening was carried
out in National Cancer Institute (NCI), USA.

Conclusion:

Compound 3e (2-(3-((6-chloro-1-oxo-2,3-dihydro-1H-inden-2-ylidene)methyl)phenoxy)-
N-(thiazol-2-yl)acetamide), exhibited highest growth inhibition against the leukaemia (61.47%),
non-small cell lung cancer (79.31%) and breast cancer (62.82%) cell lines.
Ambulatory Blood Pressure Monitoring in Type 2 Diabetes Mellitus: A Cross-sectional Study
Authors: Gunawan Florence , Ng Hui Yi , Gilfillan Christopher , Anpalahan Mahesan
Published: June 2018

Background:

Ambulatory blood pressure (ABP) monitoring in type 2 diabetes (T2DM)
is not yet routine in clinical practice.

Objectives:

To quantify abnormal ABP patterns and their associations with diabetic complications,
and to assess the reliability of office blood pressure (OBP) for assessing BP in T2DM.

Methods:

In a cross-sectional study, eligible patients with T2DM underwent OBP and 24- hour
ABP measurements under standardized conditions and screening for diabetic complications.

Results:

56 patients (mean age 67 ± 10 years, males 50%) completed assessment. 43(73%) had a
known history of hypertension. Non-dipping and nocturnal systolic hypertension (SHT) were prevalent
in 31(55%) and 32(57%) patients, respectively. 16(29%) demonstrated masked phenomenon,
but only three (7%) demonstrated white coat effect. Nocturnal SHT had a significant association
with composite microvascular complications independent of daytime systolic BP control (adjusted
odds ratio (OR) 1.72(CI 1.41-4.25). There was no association between other abnormal ABP patterns
and diabetic complications. The sensitivity and specificity of OBP for diagnosing HT or assessing
BP control was 59% and 68% respectively. The positive and negative predictive values were 74%
and 52% respectively.

Conclusion:

Non-dipping, reverse dipping, nocturnal SHT and masked phenomenon are highly
prevalent in patients with T2DM with or without a known history of hypertension. Compared with
non-dipping, nocturnal SHT may be a stronger predictor of end organ damage. The reliability of
OBP for assessing BP in T2DM is only modest. Patients with T2DM are likely to benefit from routine
ABP monitoring.
Curcumin Modulates Glycolytic Metabolism and Inflammatory Cytokines via Nrf 2 in Dalton’s Lymphoma Ascites Cells In Vivo
Authors: Das Laxmidhar , Vinayak Manjula
Published: June 2018

Background:

Warburg effect is characterized by the upregulation of HIF-1 and c-Myc regulated
LDH-A, even aerobically owing to hypoxic environment and alterations in oncogenes or tumor suppressor genes
in cancer. Reduced antioxidant defence system in transformed cells favors higher ROS production, which plays
a significant role in carcinogenesis and acts as an important regulator of NF-κB. In addition, various proinflammatory
cytokines play active roles in maintenance and progression of cancer.

Objective:

In continuation with our previous studies illustrating the long-term effect of curcumin using a liver
tissue, present study was aimed to elucidate the anti-cancer effect of curcumin due to its long-term effect in the
regulation of glycolytic metabolism, NF-κB activation, expression of proinflammatory cytokines in Dalton’s
lymphoma ascites cells in vivo.

Method:

Spectrophotometric assays, RT-PCR and EMSA were performed to address the problems.

Results:

Results revealed that curcumin-induced activation of antioxidant enzymes, Nrf2 and downstream signaling
gene NQO1. Reduction of oxidative stress, down-regulation of NADPH: Oxidase, decline in ROS and
H2O2 levels were also observed. Activation of NF-κB, expression of COX2, HIF-1α and cMyc, as well as expression
and activity of LDH-A were significantly reduced by curcumin. Besides, expression of proinflammatory
cytokines was significantly down-regulated via reducing binding of nuclear protein with AP-1, NF-IL6,
ETS and NF-κB binding elements of IL-1α, IL-1β, TNF-α and IL-6 promoters, respectively.

Conclusion:

Curcumin downregulates glycolytic metabolism via modulation of stress-activated genes and reduces
oxidative stress by enhancing antioxidant defence system, which inhibits activation of NF-κB signaling
and expression of proinflammatory cytokines in Dalton’s lymphoma ascites cells in vivo.
A Longitudinal Study of Alterations of S100B, sRAGE and Fas Ligand in Association to Olanzapine Medication in a Sample of First Episode Patients with Schizophrenia
Authors: Gerasimou Charilaos , Tsoporis James N. , Siafakas Nikolaos , Hatziagelaki Erifili , Kallergi Maria , Chatziioannou Sofia N. , Parker Thomas G. , Parissis John , Salpeas Vasileios , Papageorgiou Charalabos , Rizos Emmanouil
Published: June 2018

Background & Objective: Neuroinflammation has been proposed as a major mechanism in
schizophrenic disorder. Specifically, an increase in the inflammatory response in the central nervous
system is capable of activating microglial cells, leading to the release of pro-inflammatory cytokines
and thus activating apoptotic signaling. An increase in apoptosis may underlie a potential role of immune
neuropathology in the etiopathogenesis of schizophrenia and specifically, the onset of the disorder.
We analyzed in whole blood, levels of S100B, the receptor for advanced glycation end products
(RAGE) and the apoptotic marker Fas Ligand in a sample of 13 first episode of schizophrenia twice at
baseline before the initiation of any antipsychotic medication (A) and 6 weeks later following an antipsychotic
monotherapy with olanzapine (B) and in a sample of 10 healthy controls. The S100B,
RAGE and Fas Ligand showed statistically significant differences before and after treatment; the
S100B measurements yielded a p-value of 0.004 while the soluble RAGE and Fas Ligand measurements
yielded a p=0.03, and p=0.04 respectively. The differences between cases and controls were not
statistically significant for all measurements, with the only exception being the S100B values where
both samples A and B showed significantly higher values than the controls with p=8.5x10-8 and
p=2.9x10-10 respectively.

Conclusion:

The levels of S100B, RAGE, and Fas Ligand of drug-naive first episode psychosis patients
with schizophrenia were significantly higher than that of the same medicated first episode psychosis
patients, indicating that an increase of apoptotic signaling is present at the onset of schizophrenia
and is also associated with treatment progress.
Resurgence of the Interest in Microorganisms and Plants as Sources of Secondary Metabolites for Treating Staphylococcal Infections
Authors: Mikulášová Mária
Published: June 2018

Background:

The golden era of antibiotic discovery from Actinomycetes peaked in the
middle of the 20th century and then got abandoned. Efforts to do a screening of synthetic compounds
libraries and rational target-based drug design were not successful and only a few new
classes of antibiotics have been described over the past 60 years.

Objective: This review summarizes the newest knowledge about two untapped sources of antibacterial
natural products - microorganisms and plants.

Methods:

Research and review papers of the last decades were analyzed and the data were summarizes
to present the potential sources and mechanisms of natural products, which have the potential
to cope with staphylococcal infections.

Results:

By using modern molecular biological methods, metagenomics and sequencing, it was
found out that Actinomycetes harbor many more operons coding for secondary metabolites with antimicrobial
potential than we can account for. Methods to grow uncultured microorganisms have
been developed and the uncultured microorganisms show promising potential for new antimicrobials.
The inhibition of pathogenicity of microorganisms via Quorum sensing inhibition, inhibition of
virulence factor production or biofilm formation by plant extracts offers new ways to control antibiotic-
resistant pathogens. Plant extracts with resistance modifying activity, e.g. efflux pumps inhibitors
used as antibiotic adjuvants have the potential to restore the therapeutic activity of drugs.

Conclusion:

The findings from this review article confirm that new strategies, based on secondary
metabolites of Actinomycetes, uncultured microorganisms and plants may open new ways to overcome
the post-antibiotic era.
One Image Segmentation and Discrimination Method of Live Video System Applied in Sport Game
Authors: Laiguo Han
Published: June 2018

Background:

In the field of video image processing, the segmentation and tracking method
has become a hot research field. According to the characteristics of soccer video and VAR (Video Assistant
Referee) System, in the paper, it proposes a fast algorithm of segmentation and tracking of the
players in the video.

Methods:

First, according to complementary advantages on the color expression in RGB (Red, Green,
Blue) space and HSI (Hue, Saturation, Intensity) space, it adopts the method based on combining the
main and auxiliary space to make segmentation of the objects in the video. Then, it compares with the
normalized color histogram of targets to make identification of which team the players belong to.

Results:

Finally, it adopts the context features of the players in the soccer video sequence; it combines
the method of template matching to realize the player tracking in the soccer video.

Conclusion:

The experimental results show that the tracking algorithm proposed in this paper can solve
the objects occlusion problem of the different players in the soccer match, and can track the different
players steadily, and it also can be adopted in the VAR system.
Usability Assessment of the Missouri Cancer Registry�s Published Interactive Mapping Reports: Round Two (Preprint)
Authors: Ben Ramadan Awatef Ahmed , Jackson-Thompson Jeannette , Schmaltz Chester Lee
Published: June 2018

BACKGROUND

Health-related data’s users have trouble understanding and interpreting combined statistical and mapping information. This is the second round of a usability study conducted after we modified and simplified our tested maps based on the first round’s results.

OBJECTIVE

To explore if the tested maps’ usability improved by modifying the maps according to the first round’s results

METHODS

We recruited 13 cancer professionals from National American Central Cancer registries (NACCR) 2016 conference. The study involved three phases per participant: A pretest questionnaire, the multi-task usability test, and the System Usability Scale (SUS). Software was used to record the computer screen during the trial and the users’ spoken comments. We measured several qualitative and quantitative usability metrics. The study’s data was analyzed using spreadsheet software.

RESULTS

In the current study, unlike the previous round, there was no significant statistical relationship between the subjects’ performance on the study test and the experience in GIS tools (P = .17 previously was .03). Three out of the four (75%) of our subjects with a bachelor’s degree or less accomplished the given tasks effectively and efficiently. This study developed a comparable satisfaction results to the first round study, despite that the previous round’s participants were highly educated and more experienced with GIS.

CONCLUSIONS

By considering the round one’s results and by updating our maps, we made the tested maps simpler to be used by subjects who have little experience in using GIS technology, and have little spatial and statistical knowledge.
Analisis Rekam Medis Pasien Diabetes Mellitus Melalui Implementasi Teknik Data Mining di RSUP Dr. Sardjito Yogyakarta
Authors: Salim Marko Ferdian , Sugeng Sugeng
Published: June 2018

Latar Belakang: Diabetes mellitus adalah penyakit kronis yang mempengaruhi beban ekonomi dan sosial secara luas. Data pasien dicatat melalui sistem rekam medis pasien yang tersimpan dalam database sistem informasi rumah sakit, data yang tercatat belum dianalisis secara efektif untuk menghasilkan informasi yang berharga. Teknik data mining bisa digunakan untuk menghasilkan informasi yang berharga tersebut.Tujuan: Mengidentifikasi karakteristik pasien Diabetes mellitus, kecenderungan dan tipe Diabetes melitus melalui penerapan teknik data mining di RSUP Dr. Sardjito Yogyakarta.Metode: Penelitian ini merupakan penelitian deskriptif observasional dengan rancangan cross sectional. Teknik pengumpulan data dilakukan secara retrospektif melalui observasi dan studi dokumentasi rekam medis elektronik di RSUP Dr. Sardjito Yogyakarta. Data yang terkumpul kemudian dilakukan analisis dengan menggunakan aplikasi Weka.Hasil: Pasien Diabetes mellitus di RSUP Dr. Sardjito tahun 2011-2016 berjumlah 1.554 orang dengan tren yang cenderung menurun. Pasien paling banyak berusia 56 - 63 tahun (27,86%). Kejadian Diabetes mellitus didominasi oleh Diabetes mellitus tipe 2 dengan komplikasi tertinggi adalah hipertensi, nefropati, dan neuropati. Dengan menggunakan teknik data mining dengan algoritma decision tree J48 (akurasi 88.42%) untuk analisis rekam medis pasien telah menghasilkan beberapa rule.Kesimpulan: Teknik klasifikasi data mining (akurasi 88.42%) dan decision trees telah berhasil mengidentifikasi karakteristik pasien dan menemukan beberapa rules yang dapat digunakan pihak rumah sakit dalam pengambilan keputusan mengenai penyakit Diabetes mellitus.
Pemberdayaan Masyarakat Desa Panjangrejo Bantul Yogyakarta sebagai Upaya Mewujudkan Desa Sehat Gigi dan Mulut 2030
Authors: Aditama Pramudya , Ariesandy Leny Pratiwi , Naritasari Fimma , Purwanti Nunuk
Published: June 2018

Oral health problem in Indonesian has increased. Yogyakarta is the fourth province with the highest number oral health problem and the third province with the highest Effective Medical Demands (EMD) for oral health in Indonesia. This fact indicates that it needs the attention of many parties to solve this problem, especially in Yogyakarta. Through community empowerment, community will be able to independently maintain their oral health and can be expected to be one of a solution to overcome the existing problems.The establishment of Oral Health Cadre (KADEGI) is a form of community empowerment strategy in terms of human resource development. Community empowerment, using the Participatory Learning and Action (PLA) method, is very effective to help the KADEGI mastered several skills such as (a) able to do dental health education, (b) able to do early detection of oral disease and (c) able to refer oral health cases to the nearest public health services (puskesmas).The results of KADEGI's work in data collecting of oral health problem in Desa Panjangrejo showed that from 1.198 respondents who were examined, 64% of respondents had tooth cavities and 49% had debris and calculus. These data indicate that Desa Panjangrejo’s resident are still need special attention in oral health problem by various parties.
Codes and Protocols for DistillingT, controlled-S, and Toffoli Gates
Authors: Haah Jeongwan , Hastings Matthew B.
Published: June 2018

We present several different codes and protocols to distillT, controlled-S, and Toffoli (orCCZ) gates. One construction is based on codes that generalize the triorthogonal codes, allowing any of these gates to be induced at the logical level by transversalT. We present a randomized construction of generalized triorthogonal codes obtaining an asymptotic distillation efficiencyγ→1. We also present a Reed-Muller based construction of these codes which obtains a worseγbut performs well at small sizes. Additionally, we present protocols based on checking the stabilizers ofCCZmagic states at the logical level by transversal gates applied to codes; these protocols generalize the protocols of. Several examples, including a Reed-Muller code forT-to-Toffoli distillation, punctured Reed-Muller codes forT-gate distillation, and some of the check based protocols, require a lower ratio of input gates to output gates than other known protocols at the given order of error correction for the given code size. In particular, we find a512T-gate to10Toffoli gate code with distance8as well as triorthogonal codes with parameters[[887,137,5]],[[912,112,6]],[[937,87,7]]with very low prefactors in front of the leading order error terms in those codes.
O fio da memória na ficção de Francisco José Viegas
Authors: Franco Adenize Aparecida
Published: June 2018

Este artigo apresenta, com base na análise do romance português contemporâneo Lourenço Marques (2002), de Francisco José Viegas, algumas considerações a respeito da constituição da memória e das identidades configuradas no contexto pós-colonial que atingiu a África de língua portuguesa e pós-Revolução dos Cravos, em Portugal. Destaca-se, num primeiro momento, a verificação e catalogação de romances contemporâneos publicados em língua portuguesa nas duas últimas décadas e que estabelecem relações com a memória histórica recente de países mantidos em regimes totalitários. Subsequentemente realiza-se a análise do romance Lourenço Marques enquanto narrativa que configura tais elementos.---DOI: http://dx.doi.org/10.22409/abriluff.2018n20a438
Sob e sobre o autoritarismo do silêncio: marcas da narrativa portuguesa no pós-1974
Authors: Coelho Gislene Teixeira
Published: June 2018

No livro Exortação aos crocodilos, de António Lobo Antunes, eixos de forças pressionam um grupo de quatro mulheres, no final da década de 70, no período pós-Salazar; por conseguinte, reações de mal-estar fecundam no romance, em que vozes femininas expressam organicamente – pelo corpo, no corpo – reações a tempos de tamanha apreensão e instabilidade. Embora o livro represente o período pós-ditadura, o peso e a simbologia da censura e da repressão expressam-se sensivelmente no presente das quatro mulheres, à semelhança de uma presença secreta, não revelada, indizível, e manifestam-se como uma ainda autoridade. Um silêncio perpassa a obra no sentido de traduzir tempos de uma democracia ineficiente, em que prevalece a manutenção dos segredos. Não obstante, a obra revela instantes em que o segredo, impulsionado pelas paixões, verte a lei do silêncio, de modo a provocar discursivamente o efeito da desobediência, da desautorização da lei e da ordem. Este artigo projeta sua discussão em torno do potencial de revelação dos segredos, cujas aparições instantâneas merecem ser iluminadas no intuito de acolher testemunhos em tempos de amnésia e anistia.---DOI: http://dx.doi.org/10.22409/abriluff.2018n20a481
Cultural differences and similarities between German and Chinese internal audit functions
Authors: Eulerich Marc , Westhausen Hans-Ulrich
Published: June 2018

Cultural differences influence the behavior of companies, including management styles, relationships with employees, stake- and shareholders or social responsibility. Obviously, the concept of corporate governance encompassing the Internal Audit Function (IAF) is seen differently in different cultures. Therefore, conformance with the globally effective “International Professional Practice Framework” (IPPF) for Internal Auditors presuming a culture-free, completely homogeneous IAF with uniform working standards worldwide, seems more than difficult. The focus of this study is to compare the IAF characteristics in China and Germany, based on data from Chief Audit Executives (CAE) from both countries. We identify more (culturally influenced) differences than similarities between the German and Chinese IAF, although there can be found a number of fundamental political, economic and cultural similarities between both countries.
Enhancing food security in arid areas of Pakistan through newly developed drought tolerant and short duration mustard (Brassica juncea L.) Canola
Authors: Mustafa Hafiz , Ejaz-Ul-Hasan E , Mahmood Tariq , Hameed Amir , Ali Qurban
Published: June 2018

Food security is the crucial global issue, especially in developing countries
like Pakistan. Since edible oil is an essential food item, its persistent
paucity in the country and huge import for meeting domestic requirements,
has attained it second largest import item after petroleum products. The aim
of present study is qualitative and quantitative evaluation of newly
developed short duration and drought tolerant canola quality Brassica juncea
lines ZBJ-06012 and ZBJ-08051 to overcome the unfavorable edible oil
situation in the country. Thirteen lines were evaluated in randomized
complete block design (RCBD) for seed yield, oil quality, maturity period
and drought tolerance under different agro-climatic zones both in irrigated
and arid areas across the Punjab province at eight locations in Micro Yield
Trials during Rabi season 2012-13 and 2013-14. Presently, grown non-canola
mustard varieties Khanpur Raya and Anmol Raya were used as check varieties.
Brassica napus cultivars Punjab canola and Faisal canola were also included
in the trials for comparison study of mustard and rapeseed genotypes. Data
for all traits under observation was analyzed through Principle Component
Analysis (PCA) to evaluate the best performing lines in irrigated as well as
in rain fed areas. Principal Component Analysis showed first 2 PCs having
Eigen value >1 explaining 76.4% and 72% of the total variation at irrigated
areas and rain fed areas respectively. The mean seed yield was also compared
by Least Significant Difference (LSD) test to study the significance at 5%
probability level. Canola quality B. juncea lines ZBJ-06012 and ZBJ-08051
have shown good adaptability, early maturity, non-shattering, disease and
drought tolerance traits with high yield potential in comparison with
presently grown Brassica napus cultivars ?Punjab Canola? and ?Faisal
Canola?. Due to these prominent features, these lines have a great scope for
motivating farmers to grow canola quality B. juncea when compared with B.
napus and non-canola B. juncea. Future challenges demand further development
of high yielding, short duration and aphid tolerant mustard cultivars having
high oil content and canola quality. There is a great potential of
exploiting genetic variability in the existing B. juncea material to achieve
the aforesaid goals by using conventional plant breeding techniques.
Genetic variability for yield and yield components in Jerusalem artichoke (Helianthus tuberosus L.)
Authors: Lakic Zeljko , Balalic Igor , Nozinic Milos
Published: June 2018

Investigation of quantitative traits of Jerusalem artichoke populations was
conducted on the experimental field of the Agricultural Institute of the
Republic of Srpska in Banja Luka, during 2013 and 2014. The material was
collected in the wider area of Republic of Srpska. The following populations
were analyzed: Srbac, Modrica, Pivara, Lazarevo, Bosna, Vrbas, Gradiska and
Aleksici. The trial was arranged in a randomized complete block design with
three replications. The following parameters were analyzed: tuber weight
(g), plant height (cm), stem number/plant, average stem thickness (cm),
green mass yield/plant (kg), and dry mass yield/plant (kg). Average tuber
weight ranged from 36.7 g (Bosna) to 61.0 g (Lazarevo). Plant height ranged
from 1.55 m (Lazarevo) to 2.20 m (Aleksici). Stem number/plant varied from
2.2 (Aleksici) to 5.3 (Modrica). Stem thickness was between 1.24 cm (Bosna)
and 2.11 cm (Aleksici). The population Bosna had the lowest average yield of
green mass and dry mass yield/plant, while the highest mean value had
population Aleksici. Broad sense heritability varied from 34.66% (plant
height) to 50.99% (dry mass yield/plant). Highly significant positive
correlations between plant height and stem thickness (r = 0.874), stem
thickness and green mass yield (r = 0.919), stem thickness and dry mass
yield (r = 0.902) were established. Jerusalem artichoke populations were
clustered into two groups, and the first group was composed of two
sub-groups. The results of these studies will allow choice of Jerusalem
artichoke populations with better quantitative traits, and their inclusion
in the program of creating new varieties.
The influence of wheat genotype and environmental factors on gluten index and the possibility of its use as bread quality predictor
Authors: Sekularac Andrej , Torbica Aleksandra , Zivancev Dragan , Tomic Jelena , Knezevic Desimir
Published: June 2018

Gluten index is an indicator of gluten strength as well as a parameter which
simultaneously defines its quantity and quality. If compared to the
farinographic and extensographic methods, gluten index determining is
faster, less complicated and requires smaller amount of flour. The aim of
this study has been to determine the significance of the influence of
genotype and environmental factors on the value of gluten index and
usability of these parameters as indicators and predictors of bread quality.
Five local varieties of winter wheat (Simonida, NS 40S, Rapsodija, Pobeda,
Zvezdana) were grown in a macro-experiment carried out in three locations
(Novi Sad, Cacak, Sombor) during two seasons (2011/2012 and 2012/2013).
Gluten index value determination was achieved by using ICC standard method
155 (1996), with a slight modification that included mechanical washing of
gluten (Theby). Statistical analysis was performed by using IBM SPSS
Statistics 20. Variance analysis revealed a statistically significant effect
of genotype on gluten index value, whereas the influence of environmental
factors, as well as the interaction of two factors, had no statistical
significance. There was no correlation between the values of gluten index
and meteorological factors such as average temperature and total
precipitation during the phenophase of grain filling, and in the period from
the beginning of flowering until the harvest. However, medium-strong
negative dependence was found between gluten index and the index of heat
stress, as well as between gluten index and the number of days with
temperatures above 30?C. Weak negative dependence was recorded between
gluten index and bread volume. Based on the value of gluten index, gluten
varieties used in our study can be described as strong. Genotype proved to
be the only cause of statistically significant variation of gluten index.
Genetic variability parameters of yield and quality attributes in vegetable pea (Pisum sativum L.)
Authors: Singh Jaskanwal , Dhall R.K.
Published: June 2018

A field experiment was conducted to study the genetic variability,
heritability and genetic advance of 24 morphological traits and three
biochemical traits in 47 genotypes of vegetable pea. The analysis of
variance showed significant differences among genotypes for all the
characters under study. Highest coefficient of variation was observed for
number of podding nodes per plant and highest phenotypic and genotypic
coefficients of variation were recorded for seed yield per plant followed by
number of primary branches per plant and green pod yield per plant. Very
high heritability estimates were observed for days to last pod picking
(97.63) followed by plant height (97.40), days to first pod picking (96.78)
and shelling percentage (95.56) while genetic advance as percentage of mean
was found high for seed yield per plant (65.95) and primary branches per
plant (58.40). High heritability along with moderate to high genetic advance
was predicted in case of pod weight and number of seeds per pod, which
indicated the role of additive gene action for the inheritance of these
traits and therefore, selection could be used for improving these traits.
Evaluation of combining ability and genetic components in sunflower
Authors: Jockovic Milan , Jocic Sinisa , Prodanovic Slaven , Cvejic Sandra , Ciric Mihajlo , Canak Petar , Marjanovic-Jeromela Ana
Published: June 2018

Evaluation of genetic material involved in breeding proces is of great
importance in order to choose the most valuable genotypes with ability to
efficiently combine desirable genes in progeny. The objective of this study
was to utilize diallel method in order to estimate mode of inheritance,
heterosis effect, combining abilities and components of genetic variance for
important properties in sunflower and to identify those genotypes that can
make progress in sunflower breeding. Present research had been carried out
during 2012 and 2013 growing seasons. Evaluation included 6 sunflower
genotypes and their 15 combinations which were crossed according to
incomplete diallel. For seed yield/plant dominance of better parent (d+) was
expressed as a mode of inheritance, while regarding thousand seed weight the
most common modes of inheritance were dominance (d+) and partial dominance
of better parent (pd+). The most common mode of inheritance regarding oil
content was superdominance (sd+). Empirical estimates of combining abilities
of genotypes involved in breeding process is main startegy in evaluation of
breeding value. Regarding seed yield/plant significant and positive
heterosis effect (28.9%) was calculated in combination Harkovski x Rodnik
(P3xP5), while the highest heterosis effect for oil content (12.8%) was
determined in combination Harkovski x Amaian (P3xP6). Combining ability
analysis indicated that both genetic components, additive and non-additive,
were important in expression of investigated traits. Components of genetic
variance indicated prevalence of dominant component (H) compared to additive
(D) and higher concentration of dominant genes (u) compared to recessive
(v), in all investigated traits.
Genetic evaluation of body weight traits in Iranian native Ghezel sheep
Authors: Baneh H. , Ahmadpanah J.
Published: June 2018

The aim of the current study was to estimate genetic parameters and trends
for body weight traits at different ages in Ghezel lambs. Traits included
were birth weight (BW), 3-month weight (3MW), 6-month weight (6MW), 9-month
weight (9MW), and yearling weight (YW). Data and pedigree information used in
the present study were collected at the Breeding Station of Ghezel sheep
during 1986-2009. (Co) variance components were estimated using REML
procedure and breeding values of animals were predicted with Best Linear
Unbiased Prediction (BLUP) methodology under univariate analysis. Three
different animal models were fitted. The models consisted of the direct
additive genetic effect but differed in combinations of maternal additive
genetic and maternal permanent environmental effects. Genetic trends for each
trait were obtained by regressing the means of predicted breeding values on
year of birth. The estimates of direct heritability were 0.285, 0.371, 0.388,
0.450 and 0.179, respectively. Also, the maternal heritability was estimated
0.113, 0.031, 0.021 and 0.030 for BW, WW, 6MW and 9MW, respectively. Direct
genetic trends were positive and significant for BW, WW, 6MW (p<0.01), 9MW
and YW (p<0.05) and were obtained 2.34, 46.20, 55.11, 33.40 and 24.01
(g/year), respectively. Also, maternal trends for BW, WW, 6MW and YW were
positive and highly significant (p<0.01) and were 3.37, 17.05, 12.56 and
16.30 (g/year), respectively. The results indicated that considering maternal
effects in the statistical model make accurate estimates of genetic
parameters. Also, improvement of growth traits in Ghezel sheep seems to be
likely in selection programs.
Effect of salinity and drought stress on germination and early seedlings growth of bread wheat (Triticum aestivum L.)
Authors: Jovovic Mirjana , Tunguz Vesna , Mirosavljevic Milan , Przulj Novo
Published: June 2018

Salinity is one of the most important environmental stresses that limits soil
fertility and has adverse effects on plant growth. In order to increase
wheat production under saline conditions, it is necessary to better
understand genotypic difference, the physiological and biochemical processes
of salt tolerance in wheat. The aim of this study was to determine the most
tolerant winter wheat varieties against salinity and osmotic stress at
germination stage and early seedlings growth. The salinity and osmotic
stress were simulated in controlled environmental conditions by adding
different concentrations of NaCl and mannitol solution to the growing media
of five winter wheat variety. In all studied varieties the benchmark water
potential in which they had germinated and had a good seedlings growth was
of -0.3MPa. Under the stronger stress, -0.6 MPa, all varieties showed
reduction in the all examined parameters. The variety Bosanka, had the
highest final germination and germination energy under both mannitol and
salt stress treatments. The parameters defining the development or
percentage of strong seeds, coleoptile and root length, fresh and dry weight
of root and coleoptile of a seed were more affected by water deficit stress
and salt stress than germination and germination energy. Biplot analysis
showed that wheat cultivars grown under -0.6MPa osmotic had higher values of
root/coleoptile ratio in relation to control and -0.3MPa treatment which is
the most reliable for screening properties of the genotypes for drought
resistance in seedling stage.
Inheritance of inorganic and phytic phosphorus in maize (Zea mays L.) kernel
Authors: Camdzija Zoran , Dragicevic Vesna , Vancetovic Jelena , Stevanovic Milan , Pavlov Jovan , Filipovic Milomir , Ignjatovic-Micic Dragana
Published: June 2018

A set of fifteen elite inbred lines of maize (used as mothers) and three
tester inbred lines (used as fathers) were investigated using line x tester
statistical model, including both hybrids and inbreds. Four traits were
measured: grain yield, 1000 kernel weight, phytic phosphorus (Pphy) and
inorganic phosphorus (Pi) in the kernel. Pphy content among hybrids ranged
from 2.342 to 4.812 g kg-1 and Pi content from 0.562 to 2.340 g kg-1, while
among inbreds (lines and testers) they ranged from 2.503 to 4.180 g kg-1 and
from 0.587 to 1.629 g kg-1, respectively. Correlations between the four
traits allow breeding for high Pi and low Pphy, as well as for both high Pi
and phytate, without compromising grain yield. Correlation for hybrids
between Pphy and Pi was 0.185 (p<0.05) and for inbreds 0.142
(non-significant). General combining ability/special combining ability
(GCA/SCA) values for all the traits were below 1 (very low) indicated
non-additive inheritance. In the investigated set of genotypes, multiple
selection indices should be used for simultaneous improvement of grain yield
and phosphorus profile of maize grain.
Corrigendum
Authors: Editorial E
Published: June 2018

Vojvodic S., D. Ademovic-Sazdanic (2017): Impact of Hla-B+27
subtypes with increased susceptibility to seronegative spondyloarthropathies
in Vojvodina population.- Genetika, Vol 49, No.3, 801-808.
https://doi.org/10.2298/GENSR1703801V. The authors of the above-referenced
article have requested a corrigendum to it. The article should include the
following correction in email of corresponding authors: insteed
svetlana.vojvodic021@gmail.com correct email is
svetlana.vojvodic@mf.uns.ac.rs.

 Link to the corrected article 10.2298/GENSR1703801V
Oxidation facilitated antimicrobial ability of laser micro-textured titanium alloy against gram-positive Staphylococcus aureus for biomedical applications
Authors: Parmar Vinod , Kumar Avinash , Mani Sankar Manimuthu , Datta Subhra , Vijaya Prakash G. , Mohanty Sujata , Kalyanasundaram Dinesh
Published: June 2018

Micro-textures were engineered on titanium samples by a rapid, highly repeatable, and cost effective nanosecond laser texturing process. The controlled and repeatable micro-texture was effective in the reduction of adhesion and proliferation of Staphylococcus aureus. However, the adhesion and proliferation of human bone marrow mesenchymal stem cells were found unaffected. The authors observed time-delayed saturation of oxidation on laser micro-textured Ti6Al4V as compared to pristine material yielding a super-hydrophobic surface (contact angle of ∼158.2°). An in-house setup was designed to expose a three-dimensionally laser micro-textured Ti6Al4V sample to S. aureus-spiked nutrient broth for 24 h in a closed loop continuous flow system. The authors observed a 50% reduction of S. aureus adhesion and proliferation over the laser micro-textured surface compared to pristine samples. In vitro tests confirmed that blood coagulation remains largely unaffected, while protein adsorption was decreased by fourfold on the micro-textured surfaces, a desirable property for surgical tools. Nanosecond laser micro-textured surfaces were effective in reducing S. aureus adhesion and its proliferation due to phase evolution, oxidative transformation of Ti6Al4V, and reduction of surface potential. In addition, laser based micro-texturing is a nontoxic, environment friendly green process that is also a cost effective alternative to conventional surface modification techniques such as mechanical micromachining and chemical treatments.