bluuebunny/crossref_metadata_2025 huggingface dataset:
821 Association Between Tumor Mutations and Meningioma Recurrence in Grade I/II Disease
Authors: Dullea Jonathan , Rutland John , Gill Corey M. , Ranti Daniel , Arrighi-Allisan Annie E. , Kinoshita Yayoi , McBride Russell , Bederson Joshua B. , Donovan Michael , Sebra Robert , Fowkes Mary , Umphlett Melissa , Shrivastava Raj K
Published: March 2022

INTRODUCTION:

A subset of grade I and II meningiomas, in contrast to their predicted favorable oncologic course, recur. Recent interest has been paid to the development of predictive measures to identify which tumors may necessitate more aggressive initial management or more frequent post-resection surveillance.

METHODS:

Using our tissue bank of 255 meningiomas with linked targeted next-generation sequencing, we identified 173 with at >90 days of post-surgical follow-up. We computed progression free survival cox-regression models for each of the 5% most prevalent tumor mutations corrected for tumor grade, recurrence status, and resection status. Grade III tumors were excluded due to issues with the proportional hazards assumption. We then built a multi-gene model by including all individual gene predictors with a p-value of less than 0.20. Starting with that model, we performed automated backwards selection.

RESULTS:

In the single gene analysis, ATM (HR = 5.22; 95%CI: 1.81 – 15.08), CREBBP (HR = 2.71; 95% CI = 1.15 – 6.38), and POLE (HR = 0.56; (95%CI = 0.32 – 0.97) were significantly associated with alterations in disease progression. In the multi-gene model, only POLE remained a significant predictor of recurrence after adjusting for the same clinical covariates and the genes ATM, ATR, CREBBP, RNF43, and SETD2. Backwards selection identified recurrence status, resection status, and mutations in ATM (HR = 8.14; 95%CI = 2.65 – 24.99) and POLE (HR = 0.45; 95% CI = 0.25 – 0.78) as predictive of recurrence.

CONCLUSIONS:

There is an association between ATM, CREBBP and POLE with progression free survival after accounting for tumor grade, resection extent, and recurrence status. In a muiti-gene model, POLE was the only gene found to alter survival. Backwards variable selection identified ATM as deleterious and POLE as protective.
822 Awake Craniotomy Within Glioblastoma Subgroups (GLIOMAP study)
Authors: Gerritsen Jasper , Zwarthoed Rosa , Versyck Georges , Jessurun Charissa , Pruijn Koen , Fisher Fleur , Kilgallon John , Nawabi Noah , Lien Solie Emma Larivière; , de Jong Sil , Satoer Djaina , Schouten Joost , Bos Eelke , Kloet Alfred , Tewarie Rishi Nandoe , Smith Timothy R. , Dirven Clemens M.F. , De Vleeschouwer Steven , Broekman Marike , Vincent Arnaud
Published: March 2022

INTRODUCTION:

Awake mapping has been associated with decreased neurological deficits and increased extent of resection in eloquent glioma resections. However, its impact within clinically relevant glioblastoma subgroups remains poorly understood.

METHODS:

918 patients with tumor resection for primary eloquent glioblastoma between 2010 and 2020 at four tertiary centers from Europe and the United States were included from an initial cohort of 4075 patients. Awake patients were matched with asleep patients for the overall cohort and subgroups.

RESULTS:

Overall, awake mapping led to less neurological deficits at 6 weeks (18.4% vs. 27.8%, p = 0.036) and 6 months postoperatively (26.5% vs. 41.9%, p = 0.0039), lower residual volume (mean: 1.9 vs. 6.4 ml, p = 0.0076), a higher extent of resection (mean: 95.5% vs. 85.3%; median: 99.8% vs. 94.0%, p < 0.001), and longer overall survival (median: 20.0 vs. 18.5 months, p = 0.042). Awake mapping led in the subgroups of age < 70, age = 70, preoperative NIHSS score 0-1 and preoperative KPS 90-100 to less postoperative neurological deficits at 6 weeks and 6 months. For patients in the KPS = 80 subgroup, awake mapping led to less postoperative neurological deficits at 6 months (22.0% vs. 45.9%, p = 0.026). Patients aged < 70 years undergoing awake craniotomy had on average a longer overall survival than the asleep resection group (median: 24 months vs. 20.5 months, p= 0.031). Awake mapping was an independent predictor for receiving adjuvant chemotherapy and radiotherapy (OR for no receival: 0.40, p = 0.025), gross-total resection based on residual volume (OR 2.79, p = 0.041), and gross-total resection based on extent of resection (OR 2.24, p = 0.002). Moreover, it had a positive impact on overall survival in the = 70 subgroup (HR 0.08, p = 0.033), but a negative impact on overall survival in the NIHSS = 2 subgroup (HR 3.07, p = 0.014).

CONCLUSIONS:

Awake mapping prevents postoperative neurological deterioration in eloquent glioblastoma resections for patients aged <70, aged = 70, with a preoperative NIHSS score of 0-1 or preoperative KPS of 90-100 and increases the rate of gross-total resections in all patients.
824 Development of a Preclinical Glioblastoma Platform in a Murine Model in order to optimize Diffusion Kurtosis Imaging Protocol to be able to accurately differentiate Acute and Chronic Radiation Necrosis from Tumor Recurrence
Authors: Gunasekaran Arunprasad , Lindhorst Scott , Yazdani Milad , McDonald Daniel , Kosnik Infinger Libby M. , Varma Abhay K. , Vandergrift William A. , Patel Sunil J. , Cachia David , Das Arabinda
Published: March 2022

INTRODUCTION:

Radiation induced damage in glioblastoma (GB) patients can present in a late-delayed fashion as radiation necrosis (RN) or tumor recurrence (TR). The radiographic differentiation of these entities is particularly challenging as they appear similar on magnetic resonance imaging (MRI.) Failure to differentiate these can ultimately lead to unnecessary surgery and early cessation radiation therapy. There is a need for developing novel non-invasive techniques that can reliably distinguish between radiation necrosis and tumor recurrence.

METHODS:

We orthotopically transplanted GL261 mouse glioblastoma cells into C57BL/6 mice, with successful tumor induction verified by MRI after two weeks. To consistently induce RN/TR, an aggressive radiation dose fractionation (12 Gy/60 Gy) on alternating days was used. This was completed such that one portion of the tumor received 100% dose of radiation fraction, sufficient to cause RN, whereas the tumor edge received only 50% of the dose, allowing for tumor recurrence. At four time points, MRI and diffusion kurtosis imaging (DKI) were obtained, and objective metrics such as mean, axial, and radial kurtosis and diffusivity were calculated.

RESULTS:

Our data demonstrated mice tumor recurrence and radiation necrosis on MR imaging. MRI and DKI at 2 weeks following orthotopic glioblastoma implantation demonstrated edema and gyral edema compatible with tumor recurrence. One week later, imaging sequences demonstrated continued tumor progression. This demonstrated that our proposed model for radiation induction was effective at achieving its goal of creating some areas of RN and some of TR.

CONCLUSIONS:

Our results provides an invaluable platform for the mechanistic study of acute radiation necrosis, chronic radiation necrosis, and tumor recurrence, and management of these conditions.
825 Can Applying Machine Learning on Perioperative Team Communication Data Change the Way we Predict Case-time Duration?
Authors: Ber Roee , Valliani Aly , Liu Albert , Kurland David B. , Pacione Donato R. , Oermann Eric Karl
Published: March 2022

INTRODUCTION:

Accurate case-time prediction is a critical component in improving operating room efficiency. Applying machine learning on patient and booking parameters has been shown to improve accuracy. However, the details of the actual surgical plan as determined by the surgeon pre-operatively have not been included in these predictions. In this study, we applied machine learning methods on data from perioperative team communication platform to predict case time duration.

METHODS:

The objective data collected from 535 neurosurgical cases by a perioperative team communication platform were divided to training and testing datasets (431 and 104 cases respectively). We developed a machine learning algorithm based on historical case-duration data (last 10 similar cases by the same surgeon) and compared to planning data collected from a perioperative team communication platform. We used the real case-time duration of the cases in the training dataset to train the algorithm. We then tested our model on the testing dataset and compared the accuracy of case-time prediction to the historical data alone prediction model, which is the common method used in our institution.

RESULTS:

The machine learning model combining historical and team communication data provided better accuracy in case-time prediction than historical data alone. The historical data method averaged 90.6 minutes difference in case-time from real time, and the machine learning model averaged 80.04 minutes (p=0.029). For cases longer than the case-time 50th percentile (183 minutes), the historical data method averaged 126.02 minutes difference from real time, and the machine learning model averaged 104.52 minutes (p=0.014).

CONCLUSIONS:

The actual case plan as discussed amongst the surgical team in the perioperative period provides information that is not often available otherwise. Applying a machine learning algorithm on the data captured through a team communication platform improved case time prediction compared to common methods.
829 Surgical Outcome of Rhinocerebral Mucormycosis in Corona Virus Associated Patient: A Prospective Study from a Tertiary Care Center in Eastern India
Authors: Jha Keashav Mohan , Kumar Brajesh , Kumar Dhanajay , Singh Samrendra Kumar
Published: March 2022

INTRODUCTION:

Second wave of covid19 affected India significantly with total numbers of cases 31,440,950 and total death 4,21,224. As India acheived stablity in fight against covid, another challenge emerged in the form of Mucormycosis. Mucormycosis is a serious angioinvasive infection caused by the order Mucorales and class of Mucormycetes. It is associated with high mortality in immunocompromised mainly diabetic patients if not treated agressively.

METHODS:

Our Hospital, IGIMS was declared exclusive covid facility in April 2021 and subsequently was declared dedicated hospital for Mucormycosis.During this two month period demographic, Clinical details and outcome were collected prospectively.

RESULTS:

During two month period, 500 cases were seen in OPD, 300 patients were admitted and 120 patients were operated. 47 patients have cerebral involvement. 11 patients with extensive involvement of brain including cavernous sinus were not offered surgery, because of poor pronosis. 4 patients of this group improved 5 patients died and 2 patients were discharged in moribund condition. Another 26 patients with only meningeal involvement and small lesion, with no mass effect and was treated conservatively. 16 of this group improved, Four (with poor coma score expired. Another 4 patients were transferred to other medical facilities and details of these patients are not available. 10 patients having large fungal lesion in non eloquent area along with mass effect were operated. six patients were operated with microscopic technique and 4 patients with endoscopic technique. eight patients were earlier, Covid RT-PCR positive and was treated with steroid and oxygen inhalation. Another two patient had fever , but Covid RT-PCR was negative and was treated at home with oxygen cylinder.All of them were treated with liposomal amphotrecin B. Sinus surgery was performed in all patients. Eight patient did well and was discharged from hospital in good condition. One patient, in which endoscopic cerebral exploration was done expired. Another patient was discharged with severe neurological sequlae.

CONCLUSIONS:

Patients with Rhincerebral Mucormycosis spreading outside sinonasal cavity to the base of the brain can be treated by neurosurgical intervention.
Artificial Intelligence for Survival Prediction in Brain Tumors on Neuroimaging
Authors: Jian Anne , Liu Sidong , Di Ieva Antonio
Published: March 2022

Survival prediction of patients affected by brain tumors provides essential information to guide surgical planning, adjuvant treatment selection, and patient counseling. Current reliance on clinical factors, such as Karnofsky Performance Status Scale, and simplistic radiological characteristics are, however, inadequate for survival prediction in tumors such as glioma that demonstrate molecular and clinical heterogeneity with variable survival outcomes. Advances in the domain of artificial intelligence have afforded powerful tools to capture a large number of hidden high-dimensional imaging features that reflect abundant information about tumor structure and physiology. Here, we provide an overview of current literature that apply computational analysis tools such as radiomics and machine learning methods to the pipeline of image preprocessing, tumor segmentation, feature extraction, and construction of classifiers to establish survival prediction models based on neuroimaging. We also discuss challenges relating to the development and evaluation of such models and explore ethical issues surrounding the future use of machine learning predictions.
A semi-supervised cycle-GAN neural network for hyperspectral image classification with minimum noise fraction
Authors: Reddy Tatireddy , Harikiran Jonnadula
Published: March 2022

Hyperspectral imaging (HSI) is a popular mode of remote sensing imaging that collects data beyond the visible spectrum. Many classification techniques have been developed in recent years, since classification is the most crucial task in hyperspectral image processing. Furthermore, extracting features from hyperspectral images is challenging in many scenarios. The semi-supervised classification of HSI is motivated by the Cycle-GAN method that has been proposed in this research paper. Since the proposed HSI classification method is semi-supervised, it makes extensive use of the labelled samples, which are short and have numerous unlabelled images. The research is carried out in two phases. First, to extract the spectral–spatial features, the minimum noise fraction is adopted. And, second, the classification of the semi-supervised method is done by the cycle-GANs. Subsequently, the proposed architecture is implemented on three standard hyperspectral dataset methods. As a result, the performance comparison is carried out in the same field as state-of-the-art approaches. The obtained results successfully demonstrate the supremacy of the proposed technique in the classification of HSI.
Γυροειδής αλωπεκία
Authors: Κυρμανίδου Ειρήνη
Published: March 2022

Σκοπός της διατριβής ήταν η δερματοσκοπική, αλλεργιολογική και ανοσοϊστοχημική διερεύνηση ασθενών με γυροειδή αλωπεκία. Μετά τη συλλογή του δείγματος προσωρήσαμε σε ψηφιακή καταγραφή των βλαβών και αναζήτηση συγκεκριμένων για τη νόσο δερματοσκοπικών χαρακτηριστικών, λήφθηκε ιστοτεμάχιο από την περιοχή της βλάβης και στη συνέχεια επικολλήθηκαν επιδερμικές δοκιμασίες στη ράχη των ασθενών. Στην ανοσοϊστοχημική εξέταση αναζητήθηκε η παρουσία CD4, CD8 FOXP3 και CD123 λεμφοκυττάρων και μάλιστα ανάλογα με τη χρονική διάρκεια των βλαβών. Από τη στατιστική ανάλυση των δεδομένων βρέθηκε ότι η λεμφοκυτταρική διήθηση ποικίλει ανάλογα με το στάδιο εξέλιξης της νόσου και ότι τα πλασματοκυτταροειδή δενδριτικά κύτταρα φαίνεται να συμμετέχουν στην ενδιάμεση φάση της νόσου. Επίσης, τα Τ ρυθμιστικά κύτταρα συμμετέχουν στο μικροπεριβάλλον του πάσχοντος τριχοθυλακίου και πιθανώς εμφανίζουν διαταραχή της λειτουργικότητάς τους. Επιπλέον, η παρατηρηθείσα συσχέτιση μεταξύ της παρουσίας πλασματοκυτταροειδών δενδριτικών κυττάρων και Τ ρυθμιστικών κυττάρων στην ενδιάμεση φάση ανάπτυξης των βλαβών πιθανώς υποδηλώνει διαταραχή στη μεταξύ τους επικοινωνία. Τέλος, η παρουσία τριχών δίκην θαυμαστικού σε βλάβες γυροειδούς αλωπεκίας μπορεί να χρησιμοποιηθεί ως δείκτης παρουσίας συγκεκριμένων ανοσολογικών κυτταρικών πληθυσμών.
A spatiotemporal atlas of hydropower in Africa for energy modelling purposes
Authors: Sterl Sebastian , Devillers Albertine , Chawanda Celray James , van Griensven Ann , Thiery Wim , Russo Daniel
Published: March 2022

The modelling of electricity systems with substantial shares of renewable resources, such as solar power, wind power and hydropower, requires datasets on renewable resource profiles with high spatiotemporal resolution to be made available to the energy modelling community. Whereas such resources exist for solar power and wind power profiles on diurnal and seasonal scales across all continents, this is not yet the case for hydropower. Here, we present a newly developed open-access African hydropower atlas, containing seasonal hydropower generation profiles for nearly all existing and several hundred future hydropower plants on the African continent. The atlas builds on continental-scale hydrological modelling in combination with detailed technical databases of hydropower plant characteristics and can facilitate modelling of power systems across Africa.
Bringing Lived Lives to Swift’s Asylum: a psychiatric hospital perspective
Authors: Malone Kevin M. , Cleary Eimear , Kelleher Cecily C. , Jefferies Janis , Lane Abbie , Lucey James V. , McGuiness Seamus
Published: March 2022

Background: Few “interventions” around suicide and stigma have reached into psychiatric institutions. Lived Lives is a science-arts approach to addressing suicide and stigma, informed by a psychobiographical and visual arts autopsy. The resulting artworks and mediated exhibition ( Lived Lives), has facilitated dialogue, response and public action around stigma-reduction, consistent with a community intervention. Recent evidence from Lived Lives moved us to consider how it may situate within a psychiatric hospital.

Methods: Lived Lives manifested in St. Patrick’s University Hospital (Ireland’s oldest and largest psychiatric hospital) in November 2017.   A mixed-methods approach was used to evaluate the exhibition as a potential intervention to address stigma around suicide, with quantitative and qualitative data collected via written questionnaire and oral data collected via video documentation.  Bereavement support was available. A Clinician and an artist also provided independent evaluation.

Results:  86 participants engaged with the exhibition, with 68 completing questionnaire data. Audiences included service users, policy makers, health professionals, senior hospital administrators and members of the public. 62% of participants who completed questionnaires were suicide-bereaved; 46% had experienced a mental health difficulty, and 35% had been suicidal in the past. 91% thought Lived Lives could be of benefit in the aftermath of a suicide death. Half of participants thought Lived Lives could help reduce suicidal feelings, whereas 88% thought it could benefit those with Mental Health difficulties. The emotional response was of a visceral nature, including fear, anger, sadness, disgust and anxiety.

Conclusions: Lived Lives sits comfortably in discomfort, unafraid to call out the home-truths about stigma and its pervasive and pernicious impact, and with restoring identity at its core. Lived Lives can operate within a psychiatric hospital, as well as in community. The challenge is to move it forward for greater exposure and impacts in at-risk communities.
Cognitive Stress and Learning Economic Order Quantity Inventory Management: An Experimental Investigation
Authors: Pan Jinrui , Shachat Jason , Wei Sijia
Published: March 2022

We use laboratory experiments to evaluate the effects of cognitive stress on inventory management decisions in a finite horizon economic order quantity (EOQ) model. We manipulate two sources of cognitive stress. First, we vary individuals’ participation in a 6-digit mixed number and letter memorization task involving their personal identification numbers. This exogenously increases cognitive load. Second, we introduce an intervention to reduce cognitive stress by only allowing participants to order when inventory is depleted. This restricts the order choice set. Increases in cognitive load negatively impact earnings with and without the intervention, with these impacts largely occurring in the first attempt of the task. With repetition, participants’ choices in all treatments trend to near-optimal policy adoption. However, only in the intervention and low cognitive load treatment do the majority of choices reach the optimal policy. We estimate the learning dynamics of order decisions using a Markov learning model. Estimates suggest increased cognitive load reduces the probability of switching to more profitable policies. Choice set complexity increases biases for smaller order size adjustments, leading to greater policy lock-in.
Tras la huella de ocelotl: descifrando el pasado y vislumbrando el porvenir del jaguar
Authors: Lorenzana Gustavo , Rico Yessica , Eizirik Eduardo
Published: March 2022

El jaguar, bestia majestuosa reverenciada por nuestros antepasados e icono de las selvas tropicales, es un animal con una historia fascinante. Los estudios científicos nos ayudan a develar los detalles de su épica travesía a través del tiempo y la geografía del continente americano.
Acute oropharyngeal puncture wounds: a review
Authors: Kennedy Victoria , Aldridge Paul
Published: March 2022

Oropharyngeal injuries are commonly seen in practice. Severity can range from minor to life threatening in the case of dorsal pharyngeal or oesophageal punctures. A prompt diagnosis and early aggressive surgical management may be required to prevent the development of mediastinitis and sepsis. This article will look at acute injuries and outline a systematic approach to these cases, enabling the clinician to make early decisions rather than adopting a ‘wait and see’ approach.
In situ areal mass measurement of laser shock-loaded aluminum using point-projection x-ray backlighting
Authors: Cheng Jinming , Qi Shuangxi , Liu Dongbing , Qian Weixin , Zhang Lin , Li Yinghua , Ye Yan
Published: March 2022

X-ray backlighting is been widely used today in dynamic phenomena observation. By applying proper synchronizing techniques, the in-situ data of the intensity distribution of the fragments in laser-driven shock-loaded aluminum were obtained for a particular moment using x-ray backlighting imaging. The image resolution was better than 40 µm in this context by introducing a pinhole. In order to obtain the areal mass of the fragments, a set of reference Al step wedges with certain thicknesses was employed. Furthermore, a novel, to the best of our knowledge, calibration method is introduced to calibrate the x-ray intensity distribution. It was effective to decrease the non-uniformity influence of the x-ray intensity with this calibration method by simulating a light field. After calibration, the standard deviation of 30 regions of interest reduced to 4.17%. In consequence, the areal mass distribution of the fragments is well quantified. It should be noted that the uncertainty in the areal mass conversion mainly comes from the non-uniformity of the x-ray intensity distribution with about 5% and the measurement uncertainty of the step thicknesses with less than 10%.
And the Music Keeps on Playing: Nostalgia in Paraludical Videogame Music Consumption
Authors: Diaz-Gasca Sebastian
Published: March 2022

Why listen to videogame music when you’re not playing the game? Videogame music is widely performed and consumed outside of its original medium, and the ways audiences experience the soundtrack influences how they will seek out game music long after their initial experience of play. This chapter argues that nostalgia is a key factor in this consumption, by proposing a theoretical framework with which to understand paraludical consumption and the way nostalgia affects the extra-diegetic experience of videogame music. The framework outlines the interaction of experiential associations (one’s personal encounter with memories about experiences related to the game music), sociocultural factors (collective memory and remembrance of game music), and marketing imperatives (the manufacturing of nostalgia as a commodity by the game industry) that surround paraludical music consumption. These motivators inform the way audiences interact and reengage with VGM beyond the diegesis at a personal, social, and commercial level.
El deber de insultar: Unamuno contra Alfonso XIII en los artículos de España con honra
Authors: Urrutia Jordana Ana
Published: March 2022

En este artículo destaco el ensañamiento de Miguel de Unamuno con Alfonso XIII en los ensayos que escribe para España con Honra durante el exilio del escritor en París (entre julio de 1924 y agosto de 1925). Arguyo que el antialfonsismo de Unamuno es mucho mayor del que las cartas íntimas de la época dejan entrever, y que, a diferencia de lo que se ha dado por válido sobre esta etapa del destierro, el animal político aparece claramente delineado.
Los hunos y los hotros
Authors: Borzoni Sandro
Published: March 2022

La expresión hunos y hotros, que Unamuno empleaba para definir el bando de los nacionales y el bando de los republicanos, es muy desafortunada para la comprensión de los dos fenómenos históricos en sí. Sin embargo, literariamente, tuvo grandísima resonancia. ¿Pero que entendía exactamente con esta expresión el rector honorario de Salamanca? Está claro que si Unamuno denominaba hunos y hotros a los partidarios de los dos bandos, lo hacía para destacar así la barbarie que acomunaba los actos de violencia tanto de los militares sublevados como de las izquierdas. Pero esto no es suficiente, y pienso que en la expresión se encuentran, a veces implícitamente, otras veces más rotundamente, dos otras ideas: 1) la equivalencia entre los hunos y los hotros a nivel político (dos formas, cóncava y convexa del mismo fenómeno) y 2) la degeneración de origen patológico de los españoles, contagiados por una demencia colectiva, como causa de las violencias de la guerra.

Concluye el ensayo un recuerdo de Giovanni Amendola, un diputado liberal que fue asesinado por las Camisas negras hace 95 años, antiguo amigo y corresponsal de Unamuno, víctima de la violencia y de la degeneración morbosa de los hunos.
A DIFICULDADE CONTRAMAJORITÁRIA NAS NOVAS DEMOCRACIAS: RESENHA INFORMATIVA DO ESTUDO DE TOM GERALD DALY
Authors: Herani Renato Gugliano
Published: March 2022

Resenha de: DALY, Tom Gerald. The Alchemists: questioning our Faith in courts as democracy-builders. United Kingdom: Cambridge University Press, 2017
A EMERGÊNCIA DA COVID-19 NAS EXPERIÊNCIAS FEDERAIS: O CASO DO BRASIL
Authors: Pavani Giorgia , Hermes Manuellita
Published: March 2022

Contextualização do tema: um ano após o início da pandemia do vírus SARS-CoV-2 – Covid-19 –, surgem algumas reflexões sobre a relação entre Poderes no ordenamento jurídico brasileiro, em particular quanto à interação entre a União Federal e os demais entes federativos.Objetivos: o artigo examina o caso brasileiro em um contexto comparado. A definição do quadro comparativo é de fato essencial para a compreensão dos textos (normativos e jurisprudenciais) através da reconstrução do contexto, não só jurídico, mas também cultural, constituído por elementos histórico-geográficos, socioeconômicos, bem como – neste momento histórico – estatísticos.Metodologia: aplica o método comparativo  com uma análise baseada no estudo dos formantes.Resultados: o Supremo Tribunal Federal decidiu os conflitos federativos com base na predominância do interesse comum de preservar a saúde mediante a adoção de soluções específicas de acordo com cada necessidade verificada nas realidades locais. A descentralização, por um lado, permitiu o combate à pandemia de acordo com as feições das dimensões continentais do Brasil, mas, por outro lado, revela a carência de coordenação da cooperação entre os entes federativos em face dos desafios gerados pela pandemia.
DIREITOS HUMANOS E INTELIGÊNCIA ARTIFICAL EM MATÉRIA DE IMIGRAÇÃO E REFÚGIO
Authors: Piffer Carla
Published: March 2022

Contextualização do tema: inicia-se abordando o componente humano dos processos migratórios sob a perspectiva da globalização e as mudanças verificadas a partir do desenvolvimento tecnológico. Na sequência, debruça-se sobre o contexto da revolução tecnológica e da Inteligência Artificial. Ao final, a partir do referencial dos impactos da utilização de tomada de decisão automatizada na imigração e refúgio no Canadá, o estudo discorre sobre o questionamento judicial do sistema informatizado de vistos do Reino Unido, a fim de traçar um paralelo com as normativas editadas pela União Europeia sobre o uso da Inteligência Artificial nas mais variadas áreas, destacando a preocupação do “bloco” com possíveis e prováveis ofensas aos Direitos Humanos a partir da propagação de utilização da Inteligência Artificial sem a devida cautela e respeito às normativas internas e externas em vigor.Objetivos: este artigo tem como objetivo discorrer sobre a adoção de decisões automatizadas com o uso da Inteligência Artificial na apreciação e gestão da imigração e refúgio, com vistas a destacar potenciais riscos e ofensas aos Direitos Humanos dos envolvidos.Metodologia: quanto à metodologia empregada, na fase de investigação utilizou-se o método indutivo, na fase de tratamento de dados o método cartesiano, e no relatório dos resultados foi empregada a base lógica indutiva.Resultados: verificou-se que a revolução tecnológica ora vivenciada representa uma promissora e positiva atuação para o futuro das mais variadas áreas da ciência e da própria humanidade. No entanto, notadamente quando o assunto envolve os Direitos Humanos, a IA pode se apresentar como uma ferramenta passível de questionamento, pois sua utilização não pode - e também não deve - desviar-se do comprometimento com o respeito a tais direitos, se apresentando, portanto, como uma questão não somente ética, mas também jurídica.
EL AMBIENTE Y LOS RECURSOS NATURALES EN LA CONSTITUCIÓN ARGENTINA
Authors: Castillo Argañarás Luis F.
Published: March 2022

Contextualização do tema: los desafíos que plantea la inmensa ola de innovación tecnológica son cada vez más sentidos por la humanidad en todos los aspectos de la vida diaria, especialmente en términos de sostenibilidad y recursos naturales. Para hablar de innovación, medio ambiente, nuevas tecnologías y protección jurídica, no se puede olvidar la conexión e interdependencia entre todos los temas mencionados, recordando que el derecho no puede distanciarse de la innovación, por el contrario, el derecho debe estar cerca de toda la actualidad, relacionados con el desarrollo de nuevas tecnologías y la protección de la humanidad.Objetivos: el objetivo principal de este artículo es analizar las disposiciones de la Constitución de la República Argentina en relación con el medio ambiente y los recursos naturales, teniendo en cuenta la evolución histórica del Derecho Constitucional argentino.Metodologia: metodológicamente, siguió una estrategia cualitativa y el método científico integrado por la lógica probabilística.Resultados: A partir de la reforma de 1994 se incorpora la tendencia internacional de armonizar la preservación del ambiente con los requerimientos del progreso y desarrollo. La norma guía es el Art. 41 que incorpora el concepto de desarrollo sustentable. Se consagra el derecho de los habitantes a gozar de un ambiente sano, equilibrado, apto para el desarrollo humano y para que las actividades productivas satisfagan las necesidades presentes sin comprometer a las generaciones futuras. El Estado federal tiene la obligación de arbitrar los mecanismos necesarios para proteger de manera global al ambiente.
DIREITO TRANSNACIONAL E O ESTADO: NOVAS FORMAS DE SOLUÇÃO DE CONFLITOS (PÚBLICO E PRIVADO) ANTE AS NOVAS PERSPECTIVAS PARA O DIREITO
Authors: Della Bona Carla , Fernández Cardozo James , Pilau Sobrinho Liton Lanes
Published: March 2022

Contextualização do tema: com a criação de organismos supranacionais, operou-se uma mudança tanto na amplitude da soberania estatal quanto na do Direito Internacional em si, tendo este que se contextualizar, sem se desvirtuar, para uniformizar mecanismos para a solução dos conflitos individuais transnacionais. Neste sentido, o presente artigo dividir-se-á em duas partes. Na primeira tratar-se-á do Estado (Pós)Moderno ante as novas formas de solução de conflitos, abordando-se, como paradigma, a Lex Mercatoria e a União Europeia. Na segunda parte tratar-se-á das novas perspectivas para o Direito ante a atual ordem jurídica mundial, abordando-se o Direito Transnacional como propulsor desta nova ordem jurídica.Objetivos: o presente artigo tem por objetivo demonstrar a importância do Direito Transnacional dentro na nova perspectiva global, bem como a influência do mesmo na criação de instrumentos/organismos internacionais dotados de eficácia e capacidade jurídica para proporcionar soluções à conflitos transindividuais.  Do mesmo modo, determinar a atual situação e o destino da Soberania dentro do Estado (Pós)Moderno, ante a uma nova ordem jurídica mundial.Metodologia: quanto aos aspectos metodológicos, o estudo será realizado através de pesquisa bibliográfica básica, a partir do exame da doutrina jurídica e de artigos publicados acerca do tema. O método a ser utilizado é o hipotético-dedutivo.Resultados: todos os pontos tratados neste artigo visam demonstrar a existência de um eixo trinário de Direitos – nacional, internacional e transnacional, devendo ser optimizados mecanismos e instrumentos de resolução de conflitos capazes de dar segurança e certeza do Direito para todos os atores/sujeitos inter e transnacionais.
Factors Affecting the Performance of Zakat Administration in Malaysia: An AHP Approach
Authors: Hasan Aznan , Abduh Muhamad , Hassan Rusni , Ali Engku Rabiah Adawiah Engku , Ali Engku Muhammad Tajuddin Engku , Noordin Nazrul Hazizi
Published: March 2022

The primary objective of this study is to investigate the views of zakat professionals on the factors affecting the performance of zakat administration in Malaysia. This study started with library research to critically review previous literature on zakat administration, followed by the analytical hierarchy process (AHP). This study finds that the provisions of zakat law and collection mechanism are viewed as the most critical factors influencing the performance of zakat collection and distribution mechanism and public perception are viewed as the two main factors affecting the performance of zakat distribution administration in Malaysia. This study hopes to shed some light on how to improve the administration of zakat collection and distribution, especially the importance of having a standardized legislation and regulatory frameworks for zakat administration to be applied in all states in Malaysia.
Optical Properties of Sudan Black Stain Doped PMMA Thin Films at Different Concentration and Gamma Irradiation Effect
Authors: Almusawe A.J. , Nuha F.A. , Aziz Salah. M. Abdul
Published: March 2022

In this paper, the optical properties investigated and the effect of the gamma irradiation on the optical constant in addition to the energy band gap (Eg) of Sudan black stain doped Poly Methyl Methacrylate (PMMA) thin films. Thin films of 20% Sudan black stain/PMMA doping ratio was used to prepared three concentrations (1, 0.7, 0.4) x10-3 M. all the Dye/ Polymer solution (three different concentrations) deposited on glass substrate by using a free casting method at room temperature. The UV-Visible absorbance and transmittance spectra at the 300 - 800 nm wavelength range were used to investigate the optical properties of the films. The optical constant such as linear absorption coefficient, the extinction coefficient, and Eg were calculated. Results showed an increasing in the optical properties after irradiation with γ rays with activity 16 gray/hour, while Eg was decreasing after irradiation.
Schoenorchis manilaliana M.Kumar & Sequiera (Orchidaceae): A new record for Orchidaceae of Tamil Nadu, India
Authors: Rajasekar C , Aazhivaendhan G , Rajendran R , Kumar T Senthil , Kottaimuthu Ramalingam
Published: March 2022

Schoenorchis manilaliana M.Kumar & Sequiera collected during a field expedition to Megamalai Wildlife Sancturary forms a new distributional record for the state of Tamil Nadu. The present collection is a first report from outside the type locality. A brief description, photo-plate and other details of this endemic orchid is presented here.
Bursa svetog Azela iz Nina i podrijetlo kulta ninskih svetaca zaštitnika
Authors: Maraković Nikolina , Vedriš Trpimir
Published: March 2022

Usprkos svojoj povijesnoumjetničkoj vrijednosti i simboličkom značenju, ninski relikvijar sv. Azela dosad nije bio temeljito proučen. Polazeći od nedavne pretpostavke o milanskom podrijetlu burse i reinterpretacije identiteta troje svetačkih likova prikazanih na njoj, svrha je rada rasvijetliti podrijetlo njihova kulta te predložiti novo tumačenje njihova identiteta. Prvi dio rada donosi povijesnu kontekstualizaciju podrijetla kulta (pretpostavljenih) ninskih svetaca zaštitnika sv. Ambrozija, sv. Marcel(in)e i sv. Anselma u Milanu u vrijeme karolinške/franačke prevlasti. Drugi dio rada predstavlja rezultate komparativnog povijesnoumjetničkog istraživanja same burse s naglaskom na ikonografskoj, stilskoj i tipološkoj analizi. Rezultati obaju smjerova istraživanja (onog povijesno-kontekstualnog i likovno-komparativnog) sugeriraju da središnji ženski lik na aversu burse nije sv. Marcela kako se dosad držalo, već Bogorodica te da bursa vjerojatno ipak nije milanski proizvod s prijelaza 8. na 9. stoljeće, već da je vjerojatnije izrađena nakon uspostave Ninske biskupije, ako ne i prigodom njezine obnove u 11. stoljeću.
Aportes del programa CERES a la democratización de la educación superior en Colombia
Authors: Sacristán Carrillo Edwin Estiven
Published: March 2022

El presente artículo de reflexión tiene como objeto: establecer los aportes a la Democratización de la educación superior alcanzados durante el desarrollo de la estrategia Centros Regionales de Educación Superior CERES en Colombia, entre los años 2003 al 2014. Método: reflexión crítica basado en una revisión documental, guiado por un análisis de tendencias bibliográficas. Se concluye: un sesgo defendido por el Estado Colombiano durante lo que va del siglo XXI, en el que la cobertura desde la perspectiva de la oferta y demanda fue la principal justificación para el impulso de la estrategia CERES, en nombre de la Democratización universitaria.
El devenir de la práctica pedagógica...entre el pensamiento tecnocrático y el pensamiento reflexivo investigativo
Authors: Garcia Reina Leina Lucelva
Published: March 2022

Concebir los procesos de formación en el ámbito escolar como una tarea intencionada y compartida por los diferentes actores en este escenario de naturaleza pedagógica, cultural y de socialización política por excelencia, ha tenido el encargo en las última décadas de promover saberes que pretenden desarrollar ciertas competencias previamente determinadas, y que se consolidan en proyectos curriculares como respuesta a lo establecido por un marco normativo acorde con las exigencias globales más que a un proyecto cultural de Nación. Es así como se puede reconocer a través de un recorrido histórico por diferentes latitudes a nivel de América Latina, la orientación que en diferentes épocas se le ha dado a la estructura de sus sistemas educativos con repercusión en el diseño de los programas de formación docente. Lo anterior en respuesta directa a las corrientes económicas, políticas, culturales y esencialmente epistemológicas imperantes, que de igual manera permean el ejercicio profesional del educador. Les queda a los docentes reproducir prácticas homogeneizantes o, por el contrario, asumir prácticas emancipatorias; estas últimas son posibles cuando se hace uso de la autonomía como una de las cualidades presente en las  reformas educativas en los últimos tiempos, y que se viabiliza a través del diseño y puesta en marcha de proyectos de investigación educativa, enriqueciendo así el docente su praxis y la de su comunidad de aprendizaje, Por lo tanto, es la práctica docente un proceso dinámico en donde intervienen distintos factores para la creación y recreación de saberes en contexto.
Caracterización de las pandillas salvadoreñas a través de la crónica periodística
Authors: Baltazar Landeros Edgar
Published: March 2022

Las pandillas Mara Salvatrucha 13 y Barrio 18 son las protagonistas de las crónicas periodísticas de los últimos tiempos en El Salvador. Por medio del análisis cualitativo de un corpus de crónicas sobre el fenómeno pandilleril durante los gobiernos del Frente Farabundo Martí para la Liberación Nacional (FMLN), se recupera información contenida en la narrativa periodística sobre cuatro temáticas fundamentales: 1) la génesis y expansión de las pandillas; 2) la caracterización de las pandillas por parte del periodismo de investigación, con énfasis en los fenómenos de control territorial, 3) la narrativa sobre la violencia pandilleril a través de personajes emblemáticos; y 4) el contraste entre la negociación y la confrontación que caracterizó a los gobiernos del FMLN al hacerle frente a la problemática de las maras.
Aproximación temática a la investigación sobre la interculturalidad: un análisis de copalabras a partir de mapas de densidad y proximidad en artículos de investigación indexados en Web of Science en los últimos tres años
Authors: Alzate Juan F. , Rodríguez Luisa F. , Uribe Cristian , Pirela Johann E.
Published: March 2022

La presente publicación se propone identificar áreas temáticas en la producción de conocimiento científico relacionada con el tema de la interculturalidad. Para esto, se usó el análisis de copalabras de artículos de investigación publicados en los últimos tres años (2020, 2019 y 2018), mediante un proceso de recuperación de referencias bibliográficas en las bases de datos de Web of Science. Inicialmente, se utilizó el término intercultur* para obtener un conjunto de referencias y a partir de estas realizar un mapa de densidad para cada año mediante el programa VOSviewer. Posteriormente, se hizo un proceso de recuperación de referencias con el término interculturality en la base de datos Web of Science Core Collection para analizar el indicador de producción por países y la obtención de un mapa de proximidad. En el análisis comparativo de los mapas de densidad se encontró que el área de educación, principalmente en aprendizaje de lengua extrajera e intercambio cultural, es de mayor prominencia y estabilidad en el tiempo. Además, mediante el indicador de producción, fue posible evidenciar el liderazgo de los países latinoamericanos e hispanohablantes en la producción de artículos de investigación relacionados por la palabra clave interculturality. Finalmente, se identificaron otras dos áreas de conocimiento desde el análisis del mapa de proximidad, que fueron clasificadas en las categorías de “colonialidad y territorio” y “etnicidades e inequidad”.
La interculturalidad como cohesión del turismo sostenible en el Resguardo Ticoya, Amazonas
Authors: Molina Ana Milena , Rodríguez Caldera Emilmar Sulamit , Lian Martínez María Camila
Published: March 2022

El presente artículo gira entorno a conocer la posible interdependencia entre la interculturalidad y el denominado turismo sostenible, y cómo se aplica en un escenario real, en este caso, la comunidad del resguardo Ticoya, en el Departamento del Amazonas.

Por consiguiente, a través de un estudio de caso, el análisis se centra específicamente en el territorio que comprende el Resguardo Ticoya, en el Municipio de Puerto Nariño, situado en la zona trasfronteriza entre Perú, Brasil y Colombia, entre los ríos Amazonas, Atacuari, Boyahuasú, Loretoyacu y Amacayacu. Allí se presenta una gran riqueza natural del territorio y, especialmente, la interculturalidad de congregar tres etnias: Ticunas, Cocamas y Yaguas, las cuales, desde sus prácticas culturales, han buscado construir y consolidar espacios de diálogo, reflexión y análisis para la conservación y protección de sus territorios.

En este contexto, el presente artículo es producto de un ejercicio investigativo que se ha desarrollado con la comunidad del Resguardo Ticoya desde 2016 y que tiene como objetivo realizar una reflexión sobre cómo la diversidad intercultural presente en el Resguardo (producto de la diversidad de las tres etnias que lo comprende y reflejada en la riqueza de su gastronomía, lengua, arquitectura, artesanía, música, entre otras cosas) podría convertirse en un articulador para el desarrollo de actividades propias del turismo sostenible, las cuales velen por la protección de su territorio y la conservación de su cultura.

En referente a la metodología, las fuentes de la investigación son de carácter cualitativo y parten del análisis de documentos como el Plan de Vida del Resguardo y el Plan de Desarrollo Municipal. Además, de los resultados obtenidos a partir de un ejercicio de observación participante, en este caso realizado a través de un proceso de formación colaborativa con representantes de las 22 comunidades del resguardo en el 2019.
Análisis de los componentes asociados al concepto de innovación pedagógica
Authors: Machuca Téllez Gerardo
Published: March 2022

Se presentan un artículo de investigación resultados de un análisis documental que se enfocó en los componentes asociados al concepto de innovación pedagógica. A partir de la propuesta de codificación axial, se consiguió dar cuenta de las problemáticas asociadas a este concepto, su relación conflictiva con las tecnologías de la información y comunicación (TIC), sus actores, relaciones con la cultura institucional, las clases y las perspectivas asociadas a su comprensión. En la literatura, se encuentra la necesidad de ampliar las discusiones alrededor del papel de las TIC dentro de los procesos de innovación pedagógica, así como la imperante necesidad de reflexionar respecto a las tensiones generadas al interior de las instituciones a causa de las culturas institucionales. Así, se recalca el carácter participativo y multiescalar que adquiere la innovación pedagógica en su aplicación en contextos educativos.
Series de televisión como una herramienta para la investigación social. Análisis temático, epistemológico y metodológico
Authors: Urra Canales Miguel , Neira Hernández María Paula , Ramos Tique Daniela Alejandra , Olivares Medina Ileana , Beltrán Hernandez Sharyn Hazel , Rincón Ruiz María Alejandra
Published: March 2022

Este artículo parte de la hipótesis de que la investigación social que utiliza como herramienta las series de televisión se realiza sin un componente epistemológico robusto, sin variedad metodológica y sin amplitud temática. Para comprobar esta hipótesis, se analizan 36 artículos científicos que utilizan como herramienta de investigación social las siguientes series: Breaking Bad, The X Files (Expediente X), Game of Thrones (Juego de Tronos), I Love Lucy, Los Soprano, Mad Men, Orange is The New Black, Sex and the City (Sexo en Nueva York), Star Trek y The West Wing (El Ala Oeste de la Casa Blanca). Finalmente, tras trabajar con una base de 648 registros, se llega a la conclusión de que los artículos analizados sí cuentan con referentes epistemológicos claros, una amplia gama metodológica y abordan gran variedad de temas.
Enfoques latinoamericanos en el estudio de los Movimientos Sociales
Authors: Gamba Trimiño Alexander
Published: March 2022

El estudio de los Movimientos Sociales en América Latina ha cobrado una gran relevancia desde la década de 1980. Este interés por la acción colectiva ha ido de la mano con la aparición de enfoques latinoamericanos para su estudio, los cuales han enfatizado en la relación entre un conflicto central de la sociedad y cómo este incide en la acción colectiva. El presente artículo aborda cuatro de estos enfoques: el de los movimientos populares, el de la democratización, el antineoliberal y el de la movilización indígena. Así mismo plantea cómo estos enfoques son la base para una teoría latinoamericana de los movimientos sociales que está en gestación.