bluuebunny/crossref_metadata_2025 huggingface dataset:
Risk Assessment For Readmission For Phototherapy in Neonates With ABO Hemolytic Disease
Authors: Xu Chuncai , Bao Yingying , He Yuanyuan , Zhao Jingxin , Ji Fengjuan , Wu Mingyuan , Zhu Jiajun
Published: November 2021

Background: ABO hemolytic disease of the newborn (ABO HDN) is a main risk factor for neonatal hyperbilirubinemia, which is one of the most common causes for readmission in neonates after discharge. Our objective is to assess the risk factors for readmission in neonates with ABO hemolytic disease for phototherapy.Methords: 291 neonates at gestational age ≥ 35 weeks were enrolled with the diagnosis of ABO hemolytic disease by collecting their clinical and laboratory data retrospectively. All these infants were born in Women’s Hospital School of Medicine Zhejiang University between 2018 and 2019. . Among these neonates, 36 cases were readmitted due to hyperbilirubinemia, which is defined as the study group, while the other 255 cases as the control group.Results: The study and control groups were similar on maternal and infants basic parameters (P> 0.05), as well as the complications of both infants and mothers (P> 0.05). However, we found significant differences in the concentration of initial total serum bilirubin, the onset age for phototherapy, the positive direct antiglobulin test (DAT) between two groups (P <0.05). Logistic regression analysis suggested that the age for onset phototherapy and the initial level of total serum bilirubinwere both independent risk factors for readmission in neonates with ABO hemolytic disease.Conclusions: For neonates with hyperbilirubinemia due to ABO HDN, positive direct antiglobulin test (DAT), small age for phototherapy and high initial level of bilirubin can increase the risk of readmission for phototherapy.
Ivermectin for the prevention of COVID-19: addressing potential bias and medical fraud
Authors: Hill Andrew , Mirchandani Manya , Ellis Leah , Pilkington Victoria
Published: November 2021

Background
Ivermectin is an antiparasitic drug being investigated in clinical trials for the prevention of COVID-19. However, there are concerns about the quality of some of these trials.
Objectives
To conduct a meta-analysis with randomised controlled trials of ivermectin for the prevention of COVID-19, while controlling for the quality of data.
Methods
We conducted a sub-group analysis based on the quality of randomised controlled trials evaluating ivermectin for the prevention of COVID-19. Quality was assessed using the Cochrane Risk of Bias measures (RoB 2) and additional checks on raw data, where possible.
Results
Four studies were included in the meta-analysis. One was rated as being potentially fraudulent, two as having a high risk of bias and one as having some concerns for bias. Ivermectin did not have a significant effect on preventing RT-PCR confirmed COVID-19 infection. Ivermectin had a significant effect on preventing symptomatic COVID-19 infection in one trial with some concerns of bias, but this result was based on post-hoc analysis of a multi-arm study.
Conclusions
This meta-analysis demonstrates that the currently available randomised trials evaluating ivermectin for the prevention of COVID-19 are insufficient and of poor quality.
Development of The Use of Primary Health Care Emergency Departments After Interventions Aimed At Decreasing Overcrowding: A Longitudinal Follow-up Study
Authors: Liedes-Kauppila Marja , Heikkinen Anna M. , Rahkonen Ossi , Lehto Mika , Mustonen Katri , Raina Marko , Kauppila Timo
Published: November 2021

Background: This study, conducted in a Finnish city, examined whether decreasing emergency department (ED) services in an overcrowded primary care ED and corresponding direction to office-hours primary care would modify service usage for specific gender, age or diagnosis groups. Methods: This was an observational retrospective study carried out by gradually decreasing ED services in primary care. The interventions aimed at decreasing use of EDs were a) application of ABCDE-triage combined with public guidance on the proper use of EDs, b) closure of a minor supplementary ED, and finally, c) application of “reverse triage” with enhanced direction of the public to office-hours services and away from the remaining ED The annual number of visits to office-hours primary care GPs in different gender, age and diagnosis groups (International Classification of Diseases (ICD-10) were recorded during a 13-year follow-up period. Results: The total number of monthly visits to EDs decreased slowly over the whole study period. This decrease was similar in women and men. The decrease was stronger in the youngest age groups (0-19 years). GPs treated decreasing proportions of ICD-10 groups. Recorded infectious diseases (Groups A and J, and especially diagnoses related to infections of respiratory airways) tended to decrease. However, visits due to injuries and symptomatic diagnoses increased. Conclusion: Decreasing services in a primary health care ED with the described interventions seemed to reduce the use of services by young people. The three interventions mentioned above had the effect of making the primary care ED under study appear to function more like a standard ED driven by specialized health care.
Identification of antimalarial targets of chloroquine by a combined deconvolution strategy of ABPP and MS-CETSA
Authors: Gao Peng , Liu Yanqing , Xiao Wei , Xia Fei , Chen Jiayun , Gu Liwei , Yang Fan , Zheng Liuhai , Zhang Junzhe , Zhang Qian , Li Zhijie , Meng Yuqing , Zhu Yongping , Xu Chengchao , Dai Lingyun , Wang Jigang
Published: November 2021

Background

Malaria is a devastating infectious disease that disproportionally threatens hundreds of millions of people in developing countries. In the history of anti-malaria campaign, chloroquine (CQ) has played an indispensable role, however, its mechanism of action (MoA) is not fully understood.
Methods

We used the approach of photo-affinity labeling (PAL) in the design of a chloroquine probe and developed a combined deconvolution strategy – activity-based protein profiling (ABPP) and mass spectrometry-coupled cellular thermal shift assay (MS-CESTA) – that identified the protein targets of chloroquine in an unbiased manner in this study.
Results

We developed a novel photo-affinity chloroquine analog probe (CQP), which retains the antimalarial activity in the nanomole range, and identified a total of 40 proteins that specifically interacted and photo-crosslinked with CQP, which was inhibited in the presence of excess CQ. Using MS-CETSA, we identified 83 candidate interacting proteins out of a total of 3375 measured parasite proteins. Together, we identified 8 proteins as the most potential hits which were commonly identified by both methods.
Conclusions

We found that CQ could disrupt glycolysis and energy metabolism of malarial parasites through direct binding with some of the key enzymes, a new mechanism that is different from its known inhibitory effect of hemozoin formation. This is the first report of identifying chloroquine antimalarial targets by a parallel usage of labeled (ABPP) and label-free (MS-CETSA) methods.
1-Naphthaleneacetic Acid (NAA) Reduces Sucker Growth in European Hazelnut (Corylus avellana L.)
Authors: Hill Ryan J. , King David R. , Zollinger Richard , Moretti Marcelo L.
Published: November 2021

Three 2-year field studies were conducted to evaluate 1-naphthaleneacetic acid (NAA) as a suppressant of suckers in European hazelnut (Corylus avellana L.). Treatments were basal-directed applications of NAA at 5, 10, and 20 g·L−1 a.i. applied once per season, and two sequential applications of NAA 10 g·L−1 a.i., 28 days apart, compared with 2,4-D (3.8 g·L−1 acid equivalent), and a nontreated control. Treatments were applied early in spring and repeated the following year. Both NAA and 2,4-D delayed sucker growth by 1.2- to 3.0-fold compared with the nontreated control, and response varied with experimental site and year. Sequential treatments of NAA significantly reduced sucker height and fresh weight 120 days after treatment. NAA applied in sequential treatments increased tree trunk cross-sectional area and canopy volume in two of the three experimental sites. Yield of hazelnuts increased when suckers were removed with NAA or 2,4-D compared with nontreated. Results indicate that NAA is an effective option to control suckers in hazelnuts and can help reduce herbicide and labor in sucker control.
Numerical analysis of NOX formation in CO2 diluted biogas premixed combustion
Authors: Susilo Sugeng Hadi , Wicaksono Hangga
Published: November 2021

A further investigation of premixed biogas combustion towards the NOx formation is presented in this study. The purpose of the simulation is to determine the addition of CO2 in biogas fuel to the combustion behavior of premixed biogas on NOx formation, and to determine the occurrence of NOx in the pre-mixed biogas combustion. In this study, the Counterflow Premixed Flame class is used where this class is based on the One Dim class which is the basis for simulations with a 1-dimensional domain. The Counterflow Premixed Flame class uses an axisymmetric stagnation flow domain which has been written based on the equations. Cantera uses Newton's method to solve them. Completion is carried out in two stages. The first stage is to solve the solution using the equilibrium at each z coordinate point that has been determined. Many estimation starting points are determined from the start of the program. The second stage is the recalculation process at each point and then subdivided to get a smoother solution. The premixed excess CO2 biogas fuel and air combustion analyzed using a 1-dimensional numerical study. The diluted CO2 mass fraction ranged between 0–40 %. The CH4/CO2/air volume flow rate was maintained in ±L/min. The analysis implements the 1-D Counter Flow approach. Two counterflow nozzles were 20mm in diameter and the flame stagnation point at 10 mm. The results show that NOx mass fraction formed only on a fuel-lean mixture of CH4/CO2/air and its values decreased along with CO2 added. The addition of CO2 could reduce the NO species mass fraction down to 18 %, and NO2 reduction down to 7 %. This is mainly caused by a decreasing heat release rate of NO+N↔N2+O, N+O2↔NO+O, N+OH↔NO+H, and N+CO2↔NO+CO reactions. The N+CO2↔NO+CO reaction increased as CO2 was added but its values were not as much as the decline of three other reactions
Study of fluid layer gravity motion over vertical surface
Authors: Sarukhanyan Arestak , Sarkisyan Norik , Tokmajyan Vache , Vartanyan Arevshad
Published: November 2021

This paper presents the results of studying the motion of a liquid layer along the walls of a vertically installed pipe under the action of gravity. Two-dimensional boundary layer is formed by the fluid motion relative to the hard wall on surfaces of structures (pipes, turbines, heat-and-mass transfer equipment, aircrafts, ships, etc.), which are of positive interest in engineering practice. Further upgrading of the above-mentioned structures is possible only by increasing accuracy of momentum in the boundary layer, heat and mass transfer rates calculation. It is confirmed that in the boundary layer transfer phenomena intensity (perpendicular to the wall) is due to the fluid particles velocity distribution regularities in the cross-section of the layer. Fluid velocity distribution regularities in turn are conditioned by Reynolds number according to current notions. The principal method of quantitative analysis of turbulent flow in a boundary layer suggested by Reynolds continues to be the velocity and pressure fluctuations averaging method for some timespan. The suggested model of fluid movement enables to prognosticate conditions under which in cross-sections of the boundary layer reshaping of velocity profile takes place, to carry out analytic calculation of such hydrodynamic characteristics as mean velocity of motion, layer thickness and shearing stresses acting on the wall. The difference between the suggested methods developed for calculation of flow parameters from the well-known ones is in that that calculations are made based on an integrated approach regardless of such conceptual definitions as laminar and turbulent regimes widely used in modern hydrodynamics. Obtained results and design formulas known in the literature have been compared. It has been found that the thickness of the sliding layer, determine by the proposed calculation formula, 1.17 times smaller than that determined by the currently used formula
Integrated study on obtaining oxide pellets from brown iron ore
Authors:   JSC Uralmekhanobr (scientific-research and design institute), Lopatin Iurii N. , Mushketov Anton A. ,   JSC Uralmekhanobr (scientific-research and design institute), Dmitrieva Elena G. ,   JSC Uralmekhanobr (scientific-research and design institute)
Published: November 2021

Introduction. Currently, the main raw materials for the production of cast iron and steel at metallurgical plants are iron concentrates obtained from magnetite (ferrous) quartzites, titanium-magnetite, and skarn ores. The existing technologies for processing these types of ores, which mainly include separation processes based on magnetic properties, size, separating of equally falling grains, and surface wettability allow us to produce both ordinary iron concentrates and high quality ones. The use of such schemes in the processing of brown iron ore does not allow obtaining high rates of mineral concentration. One of the methods for processing this type of ore is a roasting-magnetic scheme, which allows converting weakly magnetic (non-magnetic) forms of iron into strongly magnetic ones. Research objective is to develop the mode of magnetizing roasting of brown iron ore, technology of concentrating of the burn-out product in order to obtain iron concentrate and oxide pellets. Methods of research. The duration of heat treatment of the charge consisting of iron ore from the Abail deposit and coal from the Ekibastuz deposit and the required mass fraction of solid carbon contained in the coal are determined. Technological studies of the roasted product were carried out in order to obtain a concentrate with a mass fraction of iron at least 67%. According to the developed technology, a batch of iron concentrate was developed in order to obtain and study raw and oxide pellets. Results. The modes of magnetizing roasting of brown iron ore from the Abail deposit and cooling of the roasted material have been developed. A scheme for mineral processing of the roasted material has been developed in order to obtain a concentrate with at least 67% of iron mass fraction. The process of obtaining strong raw and roasted pellets from iron concentrate is studied. Conclusions. The developed mode of magnetizing roasting of the charge consisting of coal and ore from the Abail deposit makes it possible to obtain a roasted product with a degree of magnetization of 93%. The using of desliming of the roasted product makes it possible to remove magnetic floccules from the processing that reduce the concentrate quality, and to obtain a concentrate with a mass fraction of iron of at least 67% in the last stage of magnetic separation. From the iron concentrate, it is possible to obtain oxidized pellets with a strength of at least 200 kg/pellet at temperature of pellets firing of 1325 °C.
Environmental protection of a coal-mining region
Authors:   Ural State Mining University, Valiev Niiaz G. , Stradanchenko Sergei G. ,   Institute of Service and Entrepreneurship (branch) DSTU, Maslennikov Stanislav A. ,   Institute of Service and Entrepreneurship (branch) DSTU, Golodov Maksim A. ,   Institute of Service and Entrepreneurship (branch) DSTU, Armeiskov Vitalii N. ,   Institute of Service and Entrepreneurship (branch) DSTU
Published: November 2021

Research objective is to substantiate the relevance of mining transition to eco-friendly technologies of subsurface use. Methods of research include analyzing theory and practice of environmental technologies application and carrying out a multifactor experiment. Results. An efficiency criterion for mineral resources extraction technologies is proposed that involves reducing the effect made by the by-products of mining and processing enterprises on the state of the environment. The problem is considered of minimizing the environmental damage from storing silt coal in dumps and storages by utilizing their components. The mechanism of environmental pollution has been formulated. Aspects of metal recovery from beneficiation tailings in a disintegrator mill are investigated. A reduced threat to living matter is predicted by implementing the concept of radical waste-free processing of substandard mineral raw materials. The need to improve the processes of crushing, fine grinding, and classification of minerals in mills to reduce the waste of coal production, harmful to the environment, is noted. Conclusions and scope of the results. Deteriorated conditions of mineral deposits development raise the risk of man-made impact on the environment in coal-mining regions. The global human population grows resulting in increased resources production to respond to resource needs. The growing threat to living matter can be reduced by radical measures, the non-waste processing of substandard mineral raw materials being the priority. The research results can be helpful in the development of deposits of solid metal-containing technologically exposed ores
Kinetic criteria for evaluating the performance of roller-cone drill bits
Authors:   Ural Federal University, Ekaterinburg, Blinkov Oleg G.
Published: November 2021

Research objective is to work out a method of evaluating the performance of roller-cone drill bits by kinetic criteria. Introduction. It is difficult to determine the absolute criteria for the performance of rock cutting tools. Therefore, the relative values of wear resistance of the cutting structure of roller-cone bits and their relative mechanical rates of drilling are adopted as process criteria. Methods of research. The calculation and analysis of kinetic criteria for evaluating the performance of drill bits have significant differences. Taking them into account is important when studying various modifications of rock cutting tools. The set of kinetic criteria gives a picture of the relative performance of the bit using the model of the well bottom close to the real one. The set of kinetic characteristics (criteria) is conventionally called the kinetic datasheet of the drill bit. The key points of constructing an analytical model of the drill bit operation on the deformable well bottom have been considered. Scope of results. This technique provides for a comparative evaluation of roller-cone drill bits of various modifications, allows for finding feedback, i.e. searching for the appropriate combination of geometrical parameters of the rock cutting tool according to given kinetic characteristics. The versatile approach intended for use in the study of the performance of rock cutting tools allows the most complete and accurate evaluation of the influence of one factor or another on the final result.
Supervivencia y rendimiento de variedades de frijol con resistencia horizontal a estrés hídrico en la Sierra Nororiental de Puebla
Authors: Huerta Lara Manuel , Reyes-López Delfino , Bautista-Calles Juliana , Hernández-Zepeda J. Santos , Parraguirre-Lezama J. Conrado , Romero Arenas Omar
Published: November 2021

Introducción: El frijol es la leguminosa más cultivada del mundo. En México es el segundo cultivo más importante después del maíz y de importancia básica para el consumo humano. La selección de variedades tolerantes a déficit hídrico, constituye una estrategia para incrementar la estabilidad genética de los cultivos y disminuir las pérdidas en el rendimiento con la finalidad de definir agroecotipos específicos para el cultivo de frijol.
Método: El objetivo del trabajo fue evaluar cuatro variedades de frijol negro con resistencia horizontal a estrés hídrico bajo condiciones de temporal en dos localidades de la Sierra Nororiental del estado de Puebla. Se utilizó un diseño de bloques completos al azar con 10 tratamientos y 5 repeticiones; las variables evaluadas fueron a) supervivencia durante el ciclo fenológico del cultivo y b) rendimiento potencial con la adición de cal agrícola al suelo, por ser una práctica campesina local de cultivo de frijol en la región, durante el ciclo agrícola 2019.
Resultados: La emergencia del cultivo se registró a los 10 días después de la siembra (dds), floración (60 dds) y madurez fisiológica en 124 dds, en San Juan Acateno del municipio de Teziutlán y en Pezmatlán del municipio de Tlatlauquitepec. Las variedades de frijol Huejonapan y Acatlán sin aplicación de cal, obtuvieron el mayor rendimiento potencial con 757 y 562 kg ha-1 respectivamente en la localidad de San Juan Acateno bajo condiciones de temporal.
Conclusión: La aplicación de cal agrícola no tuvo efecto significativo en el rendimiento de las variedades mejoradas, así como en el testigo regional Michigan; sin embargo, la mayor producción se presentó en la variedad Huejonapan y Acatlán sin aplicación de cal agrícola durante el ciclo de producción agrícola 2019 para la localidad de San Juan Acateno del municipio de Teziutlán, Puebla.
Management as a necessary tool for the prevention of violence against women
Authors: Favier Meglis Rivero , Manzanares Nayra Martínez , Loor Karla Mercedes Mendoza , Zambrano Telly Yarita Macías
Published: November 2021

The chair "Women, family and Guantanamo society" in the Guantánamo province as part of its functions intends the following investigation that addresses the theme of the prevention of violence against women from its management. This has the purpose of contributing to the educational preparation of agencies and social agents as an effective response to the demands of today's Cuban society. The study assumes the methodological-materialist and historical dialectical conception with the use of general research methods, with references, aspects of historical and theoretical-methodological evolution in the sociological, psychological, pedagogical and legal areas. The diagnostic results of the study made it possible to design as a methodological proposal a management strategy for the prevention of violence against women, which is strengthened from the integration of agencies and social agents, which places the University as the most important educational agency of the community.
Local wisdom as environmental education on Kasepuhan Ciptagelar
Authors: Budiaman Budiaman , Purwandari Dian Alfia , Scorviana H. Nova
Published: November 2021

The purpose of this study is to overview the local wisdom from local knowledge and local value, which build as an environmental educational approach to Kasepuhan Ciptagelar society. This research used a qualitative approach through in-depth interviews, observation, and document evaluation from June until November 2019 on the Kasepuhan Ciptagelar society. The data analysis of this study was completed through a process of reduction, verification, and conclusions. Local wisdom at Kasepuhan Ciptagelar contains environmental education values; physical, social, and cultural-environmental educations. It shows from their attachment to nature where the laws and natural cycles become their benchmark in the agricultural system used. Activities related to the society farming system are still implemented collectively to strengthen ties between residents through cooperation, which is a characteristic of their social-environmental education and seen from cultural-environmental education. It is closely related to a series of customary rituals that must be carried out by the Kasepuhan Ciptagelar agricultural activity.
ANALYSIS OF FACTORS INFLUENCING THE STATED PREFERENCE OF ACADEMIC EMPLOYEES TOW ARDS TELECOMMUTING IN IIUM CAMPUS, GOMBAK
Authors: Ismail Farah Diyanah , Kadar Hamsa Abdul Azeez , Ibrahim Mansor
Published: November 2021

Telecommuting acts as one of the Transportation Demand Management (TDM) measures that aimed to reduce peak hour traffic congestion by allowing commuters to work from home or a nearby telecommuting centre on certa in days of the week. The increasing private vehicle usage byllUM community (staffs and students) is posing a strain on the abil ity of the existing road and the related infrastructure on-campus. The purpose of this paper is to investigate factors influencing the stated preference of the academic staffs of IIUM towards various aspects of telecommuting. About 100 respondents had participated in this study through a self-administered questionnaire survey. Four research hypotheses highlighting the relationship between the preference to telecommute and commute distance, commute time, marital status having children as well as amount of time spent on research were formulated. Among the hypotheses, only the hypothesis highlighting the preference to telecommute and married female staff with children was tested statistically significant at 95% confidence interval. On the preference to telecommute, about 68% of the respondents expressed willingness to telecommute, even though, the University does not have an official policy on telecommuting arrangement. Some of the recommendations to increase the penetration of telecommuting in IIUM are: establishing telecommuting arrangement;promoting awareness of telecommuting; implementing telecommuting pilot project and conducting further study on various other aspects of telecommuting.
DISASTER RISK REDUCTION IN MALAYSIAN URBAN PLANNING
Authors: Mohamad Amin Intan Afida , Hashim Halimaton Saadiah
Published: November 2021

Disaster risk reduction (DRR) has become one of the main agenda at the global level. This is reflected in the 'Hyogo Framework for Action (2005- 2015) Building the Resilience of Nations and Communities to Disastersâ€™ where one of the priority actions that has been agreed is to reduce the risk factors that can induce disasters. In addition, consensus was obtained during the United Nations Conference on Sustainable Development which was held in 2012 better known as Rio+20 where disaster risk reduction, resilience and risk resulting from climate change should be taken into account in urban planning. Strengthening the instruments for the implementation of disaster risk reduction and risk assessment is needed to ensure that more sustainable urban planning can be implemented in order to accommodate rapid development that goes hand in hand with rapid urban population growth in the future. This research explores the needs for disaster risk reduction in Malaysian urban planning and also explores the roles of urban planners in disaster risk reduction. Further, this study will briefly discuss on preliminary review on disaster risk reduction agendas that has been incorporated in five stages of development plans and document in Malaysian urban planning practice namely the National Physical Plan (NPP), the State Structure Plan (SSP), the Local Plan (LP), the Special Area Plan (SAP) and the Development Proposal Report (DPR).
PRESERVATION OF URBAN CULTURAL LANDSCAPE: CASE STUDY OF ROJI IN KAGURAZAKA, TOKYO
Authors: Morokuma Benika
Published: November 2021

The Landscape Law, introduced in Japan in 2004, has granted the municipal governments the regulatory power to protect cultural landscape they wish to preserve. Due to its wider coverage, the law can technically protect the landscape developed through the secondary and tertiary industries, which theoretically includes the urban cultural landscape. However, until today, no significant cultural landscape is officially designated in its capital city Tokyo, although, such urban neighborhoods with historic sense of place still exist and are highly appreciated. By examining the fifteen-year communityâ€™s effort to preserve roji (alleys) and its landscape in Kagurazaka in central Tokyo as a case study, this paper aims to examine the achievement and limitation of the communityâ€™s advocacy efforts. In conclusion, this urban community has rather viewed its landscape as a favorable living environment than cultural resources, while the academic research recognized it as historic resource and urban cultural landscape. To better preserve the urban landscape as living environment with authenticity of the place, two approaches need to be combined in the future.
FACTOR ANALYSIS OF MOTORCYCLE CRASHES IN MALAYSIA
Authors: Sultan Zahid , Ngadiman Noor Irdiana , A. Kadir Fara Dela , Roslan Nuur Fathin , Moeinaddini Mehdi
Published: November 2021

This research paper focused on factor analysis of motorcycle crashes in Malaysia. Statistics have shown that Malaysia has the highest road fatality risk (per 100,000 populations) among the ASEAN countries and more than 50% of the road accident fatalities involve motorcyclists. The research literature has shown that key factors that significantly involve in the motorcycles crashes are human factors, road and vehicle conditions and environment factors. The purpose of this research is to analyse the driving attitude, behaviour and habits of Malaysian motorcyclists especially the young students. For this purpose, a research survey (N=210) has been conducted in University Technology Malaysia (UTM) in order to perceive road user perception on key factors that contribute to motorcycle crashes in Malaysia among the young students. The results show that the highest factor that contributes to the motorcycle crashes in Malaysia is the human behavior factor, follow by road and vehicle and lastly the environment factor. Human attitude on the road is the main factor that causes a motorcycle crash. Impatience, careless, selfish and dangerous driving make driver involve an accident. Evidence recommendations are suggested to reduce the number motorcycle crash in Malaysia. Implementation of these recommendations can be helpful to reduce the number of accidents and changing the attitude of young driver.
ISLAMISATION OF TOWN PLANNING EDUCATION: A REVIEW ON THE COURSES OFFERED BY THE DEPARTMENT OF URBAN AND REGIONAL PLANNING, INTERNATIONAL ISLAMIC UNIVERSITY MALAYSIA
Authors: Ahmad Sarkawi Azila , Abdullah Alias , Md Dali Norimah
Published: November 2021

The Islamisation of the town planning education in Malaysia especially in the Department of Urban and Regional Planning, Kulliyyah of Architecture and Environmental Design, International Islamic University Malaysia (IIUM) could successfully be materialized via the smart team-teaching approach where lecturers from the town planning Department collaborate with their counterpart in the Islamic studies Kulliyyah. This paper reports a desk study on the status of Islamic inputs in the current town planning course content. Out of 140 credit hours of town planning core courses and University required courses, it was found that 34% have already embodied Islamic-related topics whilst the remaining 66% were silent. Enhancements via compatible Islamic inputs to strengthen the existing curricula need to be done for the former while for the latter new Islamic inputs need to be incorporated. This paper reiterates that the epistemological and methodological approach combined is the way forward for sustainable education.
FEEDER MODE CHOICE SELECTION BEHAVIOURAL MODELLING: THE CASE OF KTM KOMUTER, KUALA LUMPUR
Authors: Bachok Syahriah , Mohd Zin Siti Hajar Madina
Published: November 2021

Transit oriented development propagates the use of feeder services such as buses, taxis and paratransit to support the main rail trunks (Taylor, 1982; Limtanakool et.al, 2006; Alshalalfah & Shalaby, 2007). This paper attempts at explaining the preferences of passengers of a Malaysian rail service towards feeder buses, factors influencing their choices and recommendations to encourage the KTM Komuter passengers to switch mode to feeder services instead of driving theirprivate vehicles to and from stations. Using on-board intercept survey method, some results of 200 samples were analysed for the research. Findings showed that 76% of the passengers did not prefer to use the feeder. As such, the chi-square analysis did not find any socio-demographic factors such as gender, income, level of study, employment types, to be significant in explaining this mode switching behaviour. Some trip characteristics such as vehicle ownership, frequency andlength of using the KTM Komuter service also did not significantly influence the passengers' preference in using the feeder bus service. Other factors were then examined, including stationsâ€™ characteristics, usersâ€™ access and egress behaviours, travel time and distance. Therefore, in order to encourage the KTM Komuter users in using the feeder bus service, several recommendations such as providing an efficient, reliable frequency and catchment areas of feeder bus services were made.
DAYLIGHT CHARACTERISATION OF CLASSROOMS IN HERITAGE SCHOOL BUILDINGS
Authors: Maria Yohana Susan , Prihatmanti Rani
Published: November 2021

This paper studies the daylight characteristics in selected high schools that are located in heritage-listed buildings. Heritage buildings were selected in this research due the problematic condition regarding the indoor illumination level after being adaptively reused. Based on the previous research, lighting in educational institution is a critical factor because poor lighting not only isdetrimental to the occupantsâ€™ visual comfort but also might lead to visual fatigue. To achieve the objectives of this paper, daylight level measurements and observation were conducted. The results show that the daylight that penetrates into the classrooms were below the standard due to many obstructions founded in both schools. Artificial lightings were used as a supplementary during thewhole school hours since the daylight was not uniformly distributed. Thus it can be concluded that the inappropriate adaptive reusing heritage building indoor is significantly affecting the indoor light level and might lead to visual discomfort issues for students. The research findings as well as the suggestions have been delivered to the school management to overcome the issues founded.
SIDEWALK ACCESSIBILITY AT MELAKAS TRADITIONAL STREETS FOR PEOPLE WITH DISABILITIES (PwDs)
Authors: Jaafar Nor Haslina , Abdul Rahim Asiah , Abd. Samad Nur Amirah , Che Rahim Che Raiskandar
Published: November 2021

The accessibility of street as a social arena that fulfils the need for people with disabilities (PwDs) is an important consideration in the urban design of an area. With the rising number of PwDs in Malaysia, this aspect of street design is even more critical. This paper evaluates the accessibility level of sidewalk along Jalan Hang Jebat, Melaka to PwDs. On-site access audit simulation was carried out. Actual PwDs were engaged for the simulation. It was found that the sidewalk in inaccessible to PwDs due to presence of barriers and the design of the sidewalk itself. This paper suggest that the minimum requirement of MS1184:2014 must be implemented in the sidewalk design and the concept of â€˜shared spaceâ€™ can be adopted in the study area.
RESIDENT PERSPECTIVE ON CYCLING AS AN OPTION FOR TRANSPORTATION IN PUTRAJAYA
Authors: Hashim Siti Fatimah , Hashim Habsah , Shuib Kamarul Bahrain
Published: November 2021

The Federal Government and local authorities, including Putrajaya Corporation, has introduced various initiatives to promote more sustainable transportation options such as encouraging the use of public transportation, walking and cycling in order to reduce the need to travel by car. This paper discusses the findings of the study done among the local residents in Precinct 1, 10, 11, 14 and 15 Putrajaya regarding their patterns of cycling as well as their perspectives on the use of bicycles as a mode of transportation. The study employs quantitative methodology. Primary data were gathered by direct interviews at respondentâ€™s home or at the local commercial area. The study analyses residentsâ€™ awareness about the sustainability of cycling, their opinion on the lack of bicycle usage and their willingness to use bicycle as a sustainable mode of transportation. It was found that respondents were aware of the benefits of cycling but hesitant to adopt cycling as mode of transportation for their daily trips. Based on the residentsâ€™ perspective and the pattern of bicycle usage in their daily life, several suggestions are outlined at the end of the paper with the aim of promoting cycling as a choice of transportation towards greener cities and more sustainable urban neighbourhoods.
APPLICATION OF LAND USE APPROACHES IN CONTROLLING INDUSTRIAL WASTEWATER DISCHARGE INTO RIVERS
Authors: Abdullah Muhammad Faris
Published: November 2021

In Malaysia, water pollution is one of the major environmental problems facing the society at present, especially river water pollution. Despite their importance, especially as supply of water for consumption, rivers are continually being polluted by human. One of the main contributors to river water pollution in Malaysia is effluent (wastewater) discharge from industries. At present many of the measures exercised by various government agencies to control industry-related river water pollution centt:e on the use of non-land use approaches such as enforcement of legislation and use of technology. However, the use of non-land use approaches is not without its own shortcomings. Hence, this paper aims to provide some insights into the possibility of using land use approaches to achieve the same result, which is controlling industry-related river water pollution.
URBANIZATION, ENVIRONMENTAL PLANNING AND MANAGEMENT: A CHALLENGE FOR JAMAICA
Authors: Leiska J. Powell
Published: November 2021

The rapid pace of urbanization has presented numerous challenges for developing countries such as Jamaica. The effects of urbanization coupled with poor environmental and development practices have exerted tremendous pressure on the country's fragile and limited natural resources. This issue is exacerbated by poverty, poor urban planning and management and lack of enforcement of existing land use regulations. The purpose of this paper is to critically examine the challenges in reversing negative environmental trends and practices which is increasing the vulnerability of the population, economy, infrastructure and other vulnerable elements of the society to the devastating impacts of natural hazards. The growing threats from hurricanes and tropical storms has have occurred over the last 10 years have highlighted the need for more sustainable developtnent. The report concludes with a number of recommendations that are critical to address the never ending cycle of environmental degradation.
STRUCTURAL CHANGES OF THE MALAYSIAN ECONOMY AND ITS SPATIAL INCIDENCE ON REGIONAL ECONOMIC GROWTH
Authors: Mohit Mohammad Abdul
Published: November 2021

The economy of Malaysia has undergone changes from its agricultural base to import-substitution during the 1960s and finally to export-orientation after 1968, associated with an influx of significant amount of direct foreign investment (DFI). These changes of the production base of the country led to concomitant changes in the structure of employment from agriculture to rnanufacturing and finally to services. Studies so far undertaken mostly concentrate on the macro aspect of this transformation process. No attempt has been made to study the structural changes of the national economy through analyzing the production/employment structure of the regions/states of Malaysia. In spite of adopting and implementing a number regional development policies and strategies from 2MP, it is anticipated that the structural transformation has not been uniform across the different regions of the country. Therefore, this paper provides a spatial analysis of the structural changes in the structure of production and employment that has occurred across fourteen states of Malaysia. The study found that the economic growth process has been unequal across the 14 states of Malaysia, accentuating the regional disparities in income and employment growth. Both federal govenunent development expenditure and private investments in different states of Malaysia have not been proportionate to their shares of national population and this partially explains the reason for the interregional differences of economic growth in the country.
Health Education Through a Campaign and mHealth to Enhance Knowledge and Quality of Life Among Patients With Chronic Kidney Disease in Bangladesh: Protocol for a Randomized Controlled Trial (Preprint)
Authors: Sarker Mohammad Habibur Rahman , Moriyama Michiko , Rashid Harun Ur , Rahman Md Moshiur , Chisti Mohammod Jobayer , Das Sumon Kumar , Jahan Yasmin , Saha Samir Kumar , Arifeen Shams El , Ahmed Tahmeed , Faruque A S G
Published: November 2021

BACKGROUND

Despite the growing burden of chronic kidney disease (CKD), disease knowledge and understanding are still lacking, especially in Bangladesh.

OBJECTIVE

The aim of this study was to evaluate the outcome of a health education intervention in order to enhance knowledge, health-related quality of life (QOL), and motivation regarding healthy lifestyles among rural and periurban adults suffering from CKD.

METHODS

A parallel-group (1:1) randomized controlled trial is ongoing in the Mirzapur subdistrict, Bangladesh, where two groups of patients with CKD are being compared. Patients aged 18 years and over with CKD (stages 1-3) were enrolled in November 2020. Patients were randomly allocated into either the intervention group (n=63) or the control group (n=63). The control group received usual treatment, while the intervention group received health education through a CKD campaign facilitated by a nephrologist and via mHealth (ie, periodic mobile phone calls) from community health workers. Both groups were followed up for a period of 6 months. The primary endpoint is patients’ increased knowledge measured using the Chronic Kidney Disease Knowledge Questionnaire. The secondary endpoints are improved QOL measured using the standardized EuroQol 5-Dimension 5-Level (EQ-5D-5L) questionnaire as well as improvements in the levels of blood pressure, BMI, serum creatinine, fasting blood sugar, hemoglobin, cholesterol, high-density lipoprotein cholesterol, triglyceride, serum uric acid, blood urea nitrogen, and albumin to creatinine ratio.

RESULTS

Enrollment of participants began in November 2020; the intervention and follow-up were completed in May 2021. We enrolled 126 patients in the study. Patients’ mean ages were 57.97 (SD 15.03) years in the control group and 57.32 (SD 14.37) years in the intervention group. There were 45 out of 63 (71%) females in the control group and 38 out of 63 (60%) females in the intervention group. In addition, there were 38 out of 63 (60%) literate patients in the control group and 33 out of 63 (52%) literate patients in the intervention group.

CONCLUSIONS

It is expected that a combined approach, incorporating both a CKD campaign and mHealth, for health education may be an effective tool for increasing knowledge and improving QOL among patients with CKD.

CLINICALTRIAL

ClinicalTrials.gov NCT04094831; https://clinicaltrials.gov/ct2/show/NCT04094831

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/30191
Longitudinal Relationships Between Depressive Symptom Severity and Phone-Measured Mobility: Dynamic Structural Equation Modeling Study (Preprint)
Authors: Zhang Yuezhou , Folarin Amos A , Sun Shaoxiong , Cummins Nicholas , Vairavan Srinivasan , Bendayan Rebecca , Ranjan Yatharth , Rashid Zulqarnain , Conde Pauline , Stewart Callum , Laiou Petroula , Sankesara Heet , Matcham Faith , White Katie M , Oetzmann Carolin , Ivan Alina , Lamers Femke , Siddi Sara , Vilella Elisabet , Simblett Sara , Rintala Aki , Bruce Stuart , Mohr David C , Myin-Germeys Inez , Wykes Til , Haro Josep Maria , Penninx Brenda WJH , Narayan Vaibhav A , Annas Peter , Hotopf Matthew , Dobson Richard JB ,   RADAR-CNS consortium
Published: November 2021

BACKGROUND

The mobility of an individual measured by phone-collected location data has been found to be associated with depression; however, the longitudinal relationships (the temporal direction of relationships) between depressive symptom severity and phone-measured mobility have yet to be fully explored.

OBJECTIVE

We aimed to explore the relationships and the direction of the relationships between depressive symptom severity and phone-measured mobility over time.

METHODS

Data used in this paper came from a major EU program, called the Remote Assessment of Disease and Relapse–Major Depressive Disorder, which was conducted in 3 European countries. Depressive symptom severity was measured with the 8-item Patient Health Questionnaire (PHQ-8) through mobile phones every 2 weeks. Participants’ location data were recorded by GPS and network sensors in mobile phones every 10 minutes, and 11 mobility features were extracted from location data for the 2 weeks prior to the PHQ-8 assessment. Dynamic structural equation modeling was used to explore the longitudinal relationships between depressive symptom severity and phone-measured mobility.

RESULTS

This study included 2341 PHQ-8 records and corresponding phone-collected location data from 290 participants (age: median 50.0 IQR 34.0, 59.0) years; of whom 215 (74.1%) were female, and 149 (51.4%) were employed. Significant negative correlations were found between depressive symptom severity and phone-measured mobility, and these correlations were more significant at the within-individual level than the between-individual level. For the direction of relationships over time, Homestay (time at home) (φ=0.09, P=.01), Location Entropy (time distribution on different locations) (φ=−0.04, P=.02), and Residential Location Count (reflecting traveling) (φ=0.05, P=.02) were significantly correlated with the subsequent changes in the PHQ-8 score, while changes in the PHQ-8 score significantly affected (φ=−0.07, P<.001) the subsequent periodicity of mobility.

CONCLUSIONS

Several phone-derived mobility features have the potential to predict future depression, which may provide support for future clinical applications, relapse prevention, and remote mental health monitoring practices in real-world settings.
REVIEW ON CUBOSOMES
Authors: M. SARITHA , HARSHINI BOYINA , KUMARI P. V. KAMALA , RAO Y. SRINIVASA
Published: November 2021

Cubosomes are stable nanostructured liquid crystalline particles which are made of a specific group of amphiphilic lipids in definite proper ratio in water and then stabilised by biocompatible substances like triblock polymer. Cubosomes are curved bicontinuous cubic phase liquid crystals and they can split to form thermodynamically stable particulate dispersions. Cubosomes have biocompatible and bio-adhesive properties andare capable of loading 3D bilayered structure resembling honeycomb (carvenous) like structure by encapsulating lipophilic, hydrophobic and amphiphilic substances. Cubosomes are administered through different ways such as orally, parenterally and percutaneously. Cubosomes are versatile systems in their structure for drug delivery systems.
ПОВЫШЕНИЕ СБОЕУСТОЙЧИВОСТИ КМОП СФ-БЛОКОВ СМЕШАННОГО СИГНАЛА
Authors: Байков В.Д. , Герасимов Ю.М. , Петричкович Я.Я. , Раннев Н.Ю.
Published: November 2021

Проанализированы причины сбоев при воздействии отдельных ядерных частиц (ОЯЧ) в СФ-блоках смешанного сигнала в составе КМОП СБИС. Установлено, что они связаны в первую очередь с нарушением функционирования синтезаторов частот на основе ФАПЧ (PLL). Даны рекомендации по проектированию сбоеустойчивых быстродействующих СФ-блоков PLL.
ВЫСОКОЧАСТОТНАЯ МОДЕЛЬ КАТУШКИ ИНДУКТИВНОСТИ
Authors: Дмитриков В.Ф. , Исаев В.М. , Куневич А.В. , Шушпанов Д.В. , Петроченко А.Ю.
Published: November 2021

По измеренным частотным характеристикам сопротивлений дросселей, намотанных на различных ферритовых сердечниках и с разным количеством витков была построена эквивалентная схема замещения в широком диапазоне частот (0 Гц - 500 МГц). Данная схема замещения была построена с учетом физических процессов, протекающих в дросселе.
INFLUENCE OF MODERN MEDIA ON AGRICULTURAL INFORMATION DISSEMINATION: A STUDY OF POULTRY FARMERS IN OYO STATE
Authors: Sulaiman Usman
Published: November 2021

INFLUENCE OF MODERN MEDIA ON AGRICULTURAL INFORMATION DISSEMINATION: A STUDY OF POULTRY FARMERS IN OYO STATE