bluuebunny/crossref_metadata_2025 huggingface dataset:
Zur Chronologie in den Inschriften auf dem Agora-Pfeiler von Xanthos (TL 44), den betroffenen Dynasten und ihren Münzen
Authors: Müseler Wilhelm , Schürr Diether
Published: September 2018

Childs’ Rekonstruktion der Genealogien wird bestätigt: Der Pfeiler ist wahrscheinlich von Cherẽi und nicht von Cheriga errichtet worden. Die am Ende der Südseite erwähnten Schlachten fanden wahrscheinlich nicht später als 428 v. Chr. statt. Die auf der Ostseite erwähnten Aktionen sind wahrscheinlich nicht später als 424 v. Chr., weil Ertaχssiraza unmittelbar vor einer Aktion des Dynasten Teϑϑiweibi erwähnt wird und daher mit Artaxerxes I. (465–424 v. Chr.) gleichzusetzen ist. In einer zuvor berichteten militärischen Aktion erscheinen Miϑrapata, Aruwãtijesi und die „Triere des Cherẽi“. Am Beginn der Nordseite gibt es einen Sprung bis wahrscheinlich 412/411 v. Chr., als der Satrap Tissaphernes in Kaunos tätig war. Am Ende des Prosatextes ist wahrscheinlich in ]welẽder Name des Dynasten Ddenewele zu sehen, als „sein Sohn“, d. h. Cherẽis Sohn und Nachfolger.

Die griechischen Verse danach rühmen den Sohn des Harpagos, und sein Name sollte nach dem Καρικα γένος zu [Καρ.]ις ergänzt werden, nicht zu [Γεργ]ις. Die ihm zugeschriebene Tötung von sieben arkadischen Hopliten an einem Tag erklärt die sonst kryptische Zahl CII im Feldzug gegen Tlos.

Die anschließenden B-lykischen Verse gelten aber Cheriga, und das Nordgedicht mag zu seinen Lebzeiten gedichtet worden sein, weil er hier handelnd auftritt. Der einzige chronologische Fixpunkt ist die Schlacht an der Mykale 428 v. Chr., von der auf der Südseite berichtet wird. Im Westgedicht tritt eine Frau namens Muni an die Stelle des Cheriga, und das könnte seine Frau sein, die nach dem Tod des Cherẽi die Herrschaft übernommen haben könnte.

Dieses Bild von der Pfeiler-Chronologie ist vereinbar mit Müselers Chronologie der dynastischen Münzen mit den Namen von Cheriga, Teϑϑiweibi, Cherẽi und Ddenewele. Allerdings können im Rahmen dieses Konzepts andere auf dem Pfeiler vorkommende Dynasten wie Trbbẽnimi, Miϑrapata und Aruwãtijesi nicht mit den gleichnamigen Münzprägern identisch sein, mit der möglichen Ausnahme des Punamuwa. Außerdem ist der Cheriga der Münzen zwar sicher mit dem Cheriga auf dem Pfeiler identisch, aber offenbar nicht mit Cheriga (Γεργις), dem Vater des Erbbina in den Letoon-Inschriften. Doch der Dynast Waχssepddimi auf dem Pfeiler ist möglichwerweise identisch mit dem älteren der beiden Weχssere genannten Dynasten, der im Xanthostal unmittelbar nach der Herrschaft des Kuprlli Münzen prägte.
Prodigies in Republican Rome. The Absence of God
Authors: Jiménez Miguel Requena
Published: September 2018

As opposed to the traditional view of theprodigiumas a part of a divination that augurs divine wrath, in this article we regard episodes of prodigies as ancient societies’ expression of their connection with their gods. Prodigious episodes are the evidence of divine presence or absence within a community.
Una polemica cruciale: Celso e Origene in tema di corporeità
Authors: Camassa Giorgio
Published: September 2018

Riassunto

Attraverso le pagine di Celso e di Origene vediamo delinearsi due Weltanschauungen contrapposte. La prima esclude un intervento attivo di Dio nel mondo, ipostatizza l’ordine di cose esistente, privilegia rigorosamente la cura dell’anima, nega che l’uomo possa far affidamento sul corpo (e sulla carne) per raggiungere la meta cui deve tendere, irride come irragionevoli e blasfeme sia la credenza nell’incarnazione sia quella nella resurrezione. La seconda è decisamente più sfaccettata. Il corpo per un verso sembra costituire un gravame, se è vero che le creature razionali cadono in un soma a seguito della trasgressione originaria cui le conduce l’esercizio del libero arbitrio; per l’altro è anch’esso un portato della creazione divina (come tale preordinata a fin di bene) e dall’inizio il Figlio pervade il mondo nella sua consistenza materiale, sino a che si produce il decisivo evento dell’incarnazione; alla fine dei tempi avrà luogo senza dubbio la resurrezione che chiama in causa una volta di più il corpo (o comunque un corpo), in quanto l’esistere creaturale sembra inseparabile da una dotazione corporea. A partire da questo quadro complesso e almeno in parte aporetico si profila – all’interno della seconda Weltanschauung qui considerata attraverso la lente di Origene – una linea di tendenza, che cerca di sciogliere i nodi problematici persistenti negando essere la materia causa del male e rivendicando al corpo nato dalla vergine la capacità di salvare l’umanità.
The Value of Consumer Data in Online Advertising
Authors: Bourreau Marc , Caillaud Bernard , de Nijs Romain
Published: September 2018

In this paper we propose a model where consumer personal data have multidimensional characteristics, and are used by platforms to offer ad slots with better targeting possibilities to a market of differentiated advertisers through real-time auctions. A platform controls the amount of information about consumers that it discloses to advertisers, thereby affecting the dispersion of advertisers’ valuations for the slot. We first show by way of simulations that the amount of consumer-specific information that is optimally revealed to advertisers increases with the degree of competition on the advertising market and decreases with the cost of information disclosure for a monopolistic platform, competing platforms or a welfare-maximizing platform, provided the advertising market is not highly concentrated. Second, we exhibit different properties between the welfare-maximizing situation and the imperfectly competitive market situations with respect to how the incremental value of information varies: there are decreasing social returns to consumers’ data, while private returns may be increasing or decreasing locally.
Deutschland strategiefähiger machen. Ein Sachverständigenrat für strategische Vorausschau ist nötig
Authors: Bindenagel James D. , Ackermann Philip A.
Published: September 2018

Kurzfassung

Deutschland steht vor einer außenpolitischen Zäsur. Die klassischen Bezugspunkte deutscher Außen- und Sicherheitspolitik sind aufgrund zahlreicher Krisen und dem Aufbrechen der Weltordnung einem grundlegenden Wandel ausgesetzt. Dieser Wandel macht eine Neuausrichtung deutscher Politik und Strategieentwicklung unbedingt notwendig. Jedoch dominiert in Deutschland nach wie vor eine strategische Kultur der Zurückhaltung, Passivität und der moralischen Kompromisslosigkeit. Sie ist mit den neuen außen- und sicherheitspolitischen Realitäten nur schwer vereinbar. Zur Schaffung eines Ausgleichs ist die Förderung einer breiten und öffentlichen außen- und sicherheitspolitischen Debatte auf Basis undogmatischer Analysen und Prognosen eine zentrale Voraussetzung. Strategische Planung, das Entwerfen von Zukunftsszenarien sowie das Abschätzen von Risiken und Gefahren stellt eine Möglichkeit dar, einen solchen Ausgleich zu erreichen. Zwar hat die Bundesregierung den Bedarf an strategischer Analyse, Debatten und besserer Ressortzusammenarbeit erkannt. Jedoch stärkt sie mit Blick auf den jüngsten Koalitionsvertrag ausschließlich bestehende Strukturen innerhalb der Ministerien und den regierungsnahen Denkfabriken. Ein neuer Impuls für eine Förderung der (öffentlichen) strategischen Debatte könnte die Schaffung eines unabhängigen Sachverständigenrates für strategische Vorausschau darstellen, dessen Form und Aufgabenbereich sich an dem Rat der Wirtschaftsweisen orientiert.
We Are Pilots, not Horses
Authors: Chuang Andy Kai-chun
Published: September 2018

Drawing upon contributions of scholarship on power and resistance in critical organizational communication studies, this essay explores resistance as a form to shape and reinforce professionalism from Taiwanese commercial airline pilots' performed discursive practice. Interviews were conducted with Taiwanese commercial airline pilots to excavate their personal narratives, which are then presented in poetic transcription. Through the poetic transcription, this essay demonstrates Taiwanese commercial airline pilots' resistance as embodied performance of work-practices in everyday organizing; thus calling for a performative turn to study organizational power, resistance, and professionalism.
Odgojitelji i odgojna partnerstva u kontekstu ustanova ranog i predškolskog odgoja i obrazovanja
Authors: Pintar Željka
Published: September 2018

Odgoj djeteta zadaća je obitelji, odgojno-obrazovnih institucija i društva u cjelini. Zasebno razmatrano, promotrljiv je kao privatno obiteljsko pitanje u kojemu roditelji imaju dominantan utjecaj, kao dostignuće koje institucija pripisuje svojem angažmanu ili kao zahtjev šireg društva u cjelini. Radom se razmatra potreba svjesno osmišljenog, isprepletenog međuutjecaja svih odgojnih čimbenika direktno i indirektno upućenih odgoju djeteta, što odmiče od strategije povremenih i fragmentiranih nastojanja poboljšavanja uvjeta života djece vezanih uz samo jedan od navedenih konteksta. Nadalje se razmatra važnost institucionalnih odgojitelja ustanova ranog i predškolskog odgoja u procesu poticanja zajedničkog, partnerskog, podupirateljsko-unapređujućeg međuodnosa svih odgojnih faktora. Razmatraju se uvjeti realizacije, mogućnosti i načini zajedničkog djelovanja usmjerenog dobrobiti svakog djeteta.
Spolno ponašanje adolescenata, njihova informiranost i mišljenje o seksualnosti
Authors: Petani Rozana , Vulin Anđela
Published: September 2018

Prihvaćanje spolnoga identiteta te odgovorno spolno ponašanje vrlo su važan dio razvoja adolescenata. Neoprezno seksualno ponašanje u adolescenciji može imati neposredne i dugoročne posljedice. Od neposrednih su najvažnije neželjena trudnoća te spolno prenosive infekcije te dugoročna djelovanja na reproduktivno zdravlje pa i na trajanje života. Stoga, spolno ponašanje adolescenata ima značajne individualne i društvene posljedice. Da bi se mladima pomoglo, prije svega, potrebno je prihvatiti činjenicu da će većina mladića i djevojaka postati seksualno aktivna u drugom desetljeću svoga života, a upravo zbog toga odgovorna društvena i zdravstvena politika ima obavezu razviti i osigurati programe seksualnoga odgoja koji bi uključivali informacije o kontracepciji, spolno prenosivim bolestima te učinkovite mjere zaštite od neželjene trudnoće i spolno prenosivih bolesti.

Cilj je istraživanja bio utvrditi spolno ponašanje, informiranost i mišljenje adolescenata o seksualnosti. Ispitano je 36 učenika i 64 učenice u dobi 16 – 18 godina, 27 učenika i 11 učenica izjasnilo se da su spolno aktivni. Rezultati su pokazali da su učenici skloniji rizičnom spolnom ponašanju, a u skupini pitanja koja su se odnosila na znanje o spolno prenosivim bolestima, ukupno gledajući, dobiveni su rezultati zadovoljavajući jer je većina učenika pokazala određeno znanje o ispitivanoj temi. Više učenica nego učenika smatra da je zdravstveni odgoj potreban u školama, a učenice su pokazale i veću spremnost za roditeljstvom nego učenici. Usprkos određenom znanju o spolno prenosivim bolestima i u istraživanju je utvrđeno da postoji potreba za seksualnim odgojem u školama.
Važnost stvaranja discipline i unutarnje kontrole u procesu razvoja čovjeka
Authors: Hercigonja Zoran
Published: September 2018

Disciplina je važan faktor za izvođenje odgojno-obrazovnoga procesa. Disciplina se ne postiže preko noći. U radu je naglašen razvoj discipline u čovjekovu djetinjstvu i mladosti, odnosno u vremenu kada čovjek svjesno ili nesvjesno usmjerava razvoj vlastite ličnosti. Bitan utjecaj na stvaranje discipliniranoga ponašanja prvenstveno ima obitelj, zatim odgojno-obrazovne ustanove i društvena okolina u kojoj se netko nalazio. Na jedan je način razvojem discipline čovjek sebe obogaćivao za cijeli život, gdjegod se nalazio i štogod radio. U suprotnom, nediscipliniranost je dovodila do različitih oblika nepoželjnih ponašanja koja su štetila samoj osobi, ali i njezinim odnosima s drugima. Kroz povijest su se razvijale metode ili strategije za suzbijanje nediscipliniranosti, a one su nastajale na osnovi praktičnih iskustava.
The Influence of Guided Inquiry Learning Using Flash Based Invertebramedia on the Senior High School Students’ Learning Achievement
Authors: Anifatussholihah Anifatussholihah , Utami Nur Rahayu , Subekti Niken
Published: September 2018

This research aims to know the influence of guided inquiry learning with flash based Invertebramedia on the learning outcome of senior high school students. The research was done in SMA N 1 Pamotan using Quasi Experimental Design. The sample of the study was X MIPA 1 class (experimental group) and X MIPA 2 class (control group) which was taken by purposive sampling technique. The results showed that there were increasing of cognitive’s learning outcome of the experiment group was 80% and control group was 34.2%. There was a significant difference in the average of cognitive learning outcomes of the experimental group and control group. Analysis of affective and psychomotor aspects showed that learning outcome the experimental group higher that the control group. So, the activity of students during learning process was enchancement. The average of the student’s questionnaire responses after joining the learning was 84.9% in good criteria. The teacher and the students also gave good responses on the implementation of the learning in general. The conclusion of the research is the application of guided inquiry learning with Invertebramedia based on flash influence on high school student’s learning outcomes.
Analysis of the Effectiveness of Learning Models against Students’ Innovative Behaviour
Authors: Rahmawati Rizqi , Ridlo Saiful , Sukaesih Sri
Published: September 2018

Practicum become an appropriate method to give provisions in empirical experience especially for college student of Biology Education. Practicum was believed could show university students’ innovative behavior. The concrete form from using practicum method is learning model application that include learning syntax from the beginning to the end. Therefore, a research was did to analyze relation between practicum method towards innovative behaviour and the effectivity of it. Based on the result of regression analysis, all models give significance value p < 0.05 so could be known that every learning model give significance influence toward the formation of university students’ innovative behavior. Based on correlation coefficient analysis could be known that PJBL learning model give contribution value of 86.2% followed by guided inquiry of 85.4%, experiment model of 76.3% and observation model with contribution value of 64.7% toward the formation of university students’ innovative behavior. Based on the results of variance similarity analysis could be known that PJBL model is the most effictive model to form innovative behavior with difference value of 17.80 compared with other learning models. The result of research showing that all of the learning models when used on practicum relating the formation of innovative behaviour. Project based learning model gave contribution most effective towards innovative behaviour of the college students in Biology Education study program.
The Effectiveness of Teams Games Tournament with Biodomino on Ecosystem Material to Enhance Student’s Activity and Learning Outcomes in SMAN 2 Salatiga
Authors: Faris Ahmad , Pribadi Tyas Agung , HB F Putut Martin
Published: September 2018

Ecosystem is considered as a notional topic due to lack of material visualization. An effective learning media is needed to help student in learning ecosystem. There are some factors that make some schools are unable to conduct an outdoor learning, that can be overcome through the model of Team Games Tournament (TGT) as a learning method with Biodomino as a supporting learning media. This study was aimed to determine the effectiveness of TGT with Biodomino on student activity and learning outcomes in ecosystem. The method used was quasi experiment with Nonequivalent Control Group Design. Result of this study showed that 100 percent of students participated in the experiment were in active category, with 81.25% of students got score of ≥77. It is concluded that learning the ecosystem unit by using TGT method with the help of Biodomino is an effective way to increase the student activity and learning outcomes.
Analysis of the Creative Thinking Ability of Students SMA N 1 Pecangaan Jepara on Environmental Change Material
Authors: Utami Retna , Marianti Aditya , Susanti R.
Published: September 2018

Creative thinking is an ability of creating a new thought as a result from combination of previous knowledge. It is needed to be developed in the 21st century because it is importance in work world. This study aims to analyze the students’ creative thinking of SMA N 1 Pecangaan on environmental material. The research used observational method. Population is whole students of tenth grade of SMA N 1 Pecangaan. The samples used purposive samplings were X MIA 1, X MIA 2 and X MIA 4 with total number 116 students. The students’ creative thinking was tested by essay test and instrument non-test which is scoring rubric of writing article about environment problems. The result showed that students’ creative thinking of SMA N 1 Pecangaan in answering question is 14.7% very creative, 31% creative, 20.7% creative enough and 33.6% less creative. The students’ ability in writing article showed 0% very creative, 16.4% creative, 30% creative enough, 49.1% less creative and 4.3% not creative. The research concluded that the creative thinking ability of students SMA N 1 Pecangaan is low. The highest aspects of creative thinking that is reached by students are originality and fluency, while the lowest is elaboration.
The Application of Bioedutainment Strategy Using Uno Cards on the Students’ Learning Result in Invertebrate Material at Sma Institut Indonesia
Authors: Khomsah Irma , Heri B F Putut Martin , Irsadi Andin
Published: September 2018

This study aims to examine the effect of applying uno-assisted bioedutainment strategy on students’ learning outcomes in invertebrate material. This study uses a non-equivalent control group design. The population of this study is the students of class X SMA Institut Indonesia Semarang. X.4 and X.5 were selected as samples using purposive sampling technique. The result of the study showed that there were significant differences in the data of the second post tested class. T test analysis of post test students shows t count> t table. The conclusion of this study is that the learning using uno cards in invertebrate material has a positive effect on the students’ learning outcomes.
Secondary adrenal insufficiency and pituitary dysfunction in oral/transdermal opioid users with non-cancer pain
Authors: Lamprecht Andrea , Sorbello Jane , Jang Christina , Torpy David J , Inder Warrick J
Published: September 2018

Objective

To evaluate pituitary function, sexual function and quality of life (QoL) in patients on oral or transdermal opioids.

Design and methods

Cross-sectional study comparing pituitary function, QoL and sexual function in people on long-term opioid therapy (n = 40) vs an age- and sex-matched control group (n = 25). Baseline pituitary function was assessed on blood samples collected prior to 0900 h. Further testing with corticotropin (250 µg IV) and metyrapone (30 mg/kg) stimulation tests was undertaken on participants with serum cortisol <250 nmol/L. Validated questionnaires completed to assess QoL, fatigue and sexual function.

Results

Secondary adrenal insufficiency (SAI) was identified on the basis of a failed stimulation test in 22.5% of opioid users vs no controls (P = 0.01). Opioid users with SAI had a higher median morphine-equivalent daily dose (MEDD),P = 0.037 – 50% with MEDD >200 mg and 0% with MEDD <60 mg had SAI. Among male participants, testosterone was inversely associated with BMI (P = 0.001) but not opioid use. A non-significant trend to low testosterone <8 nmol/L in male opioid users (11/24 opioid users vs 2/14 control,P = 0.08) suggests a small subgroup with opioid-induced androgen deficiency. Opioid users had greater fatigue, reduced quality of life in all subsections of the SF-36 and impaired sexual function in both males and females (all scoresP < 0.001 compared to controls).

Conclusion

Long-term opioid therapy was associated with dose-related SAI in over 20% of chronic pain patients and is associated with poor quality of life, fatigue and sexual dysfunction. Obesity confounds the interpretation of opioid-induced male androgen deficiency.
Knockdown of NLRP3 alleviates high glucose or TGFB1-induced EMT in human renal tubular cells
Authors: Song Shan , Qiu Duojun , Luo Fengwei , Wei Jinying , Wu Ming , Wu Haijiang , Du Chunyang , Du Yunxia , Ren Yunzhuo , Chen Nan , Duan Huijun , Shi Yonghong
Published: September 2018

Tubular injury is one of the crucial determinants of progressive renal failure in diabetic nephropathy (DN), while epithelial-to-mesenchymal transition (EMT) of tubular cells contributes to the accumulation of matrix protein in the diabetic kidney. Activation of the nucleotide binding and oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome leads to the maturation of interleukin (IL)-1B and is involved in the pathogenic mechanisms of diabetes. In this study, we explored the role of NLRP3 inflammasome on high glucose (HG) or transforming growth factor-B1 (TGFB1)-induced EMT in HK-2 cells. We evaluated EMT through the expression of α-smooth muscle actin (α-SMA) and E-cadherin as well as the induction of a myofibroblastic phenotype. Reactive oxygen species (ROS) was observed using the confocal microscopy. HG was shown to induce EMT at 48 h, which was blocked byNLRP3silencing or antioxidant N-acetyl-L-cysteine (NAC). We found thatNLRP3interference could inhibit HG-induced ROS. Knockdown ofNLRP3could prevent HG-induced EMT by inhibiting the phosphorylation of SMAD3, P38 MAPK and ERK1/2. In addition, P38 MAPK and ERK1/2 might be involved in HG-induced NLRP3 inflammasome activation. Besides, TGFB1 induced the activation of NLRP3 inflammasome and the generation of ROS, which were blocked byNLRP3interference or NAC. Tubular cells exposed to TGFB1 also underwent EMT, and this could be inhibited byNLRP3shRNA or NAC. These results indicated that knockdown ofNLRP3antagonized HG-induced EMT by inhibiting ROS production, phosphorylation of SMAD3, P38MAPK and ERK1/2, highlighting NLRP3 as a potential therapy target for diabetic nephropathy.
Proteomic changes in uterine flushings after levonorgestrel treatment and effects on sperm function
Authors: Hernández-Silva Gabriela , Durand Marta , Larrea Fernando , Chirinos Mayel
Published: September 2018

When levonorgestrel (LNG) is given for emergency contraception during the follicular phase inhibits or delays ovulation, but also induces changes in endometrial secretions that modulate sperm functionality. In order to characterize the female reproductive tract secreted molecules that may affect human spermatozoa, we analyzed changes in the protein content of uterine flushings obtained from women during the periovulatory phase of a control and a LNG-treated menstrual cycle. Lectin affinity analysis and two-dimensional gel electrophoresis of uterine samples showed changes in protein glycosylation pattern and the presence of 31 differentially expressed proteins (8 up- and 23 down-regulated). Mass spectrometry and Western blot analyses of the differential expressed proteins showed lactotransferrin (LTF) as one of the up-regulated molecules by LNG. In this study, LTF exhibited significant dose-related effects on sperm functionality, particularly a decrease of calcium ionophore-induced acrosome reaction and protein tyrosine phosphorylation. Overall, the results indicated that LNG promoted changes in the proteome of uterine secretions that might compromise human sperm capacitation. These data further support the participation of other mechanisms of action of LNG as emergency contraceptive, in addition to those on ovulation.
Impact of Direct Acting Antiviral (DAA) Treatment on Glucose Metabolism and Reduction of Pre-diabetes in Patients with Chronic Hepatitis C
Authors: Weidner Philip , Boettche Dominik , Zimmerer Thomas , Burgermeister Elke , Teufel Andreas , Ebert Matthias P.A. , Antoni Christoph
Published: September 2018

Background & Aim: With the development of direct acting antiviral agents (DAA) chronic hepatitis C virus (HCV) infection has become curable in most patients. Since HCV infection is known to have direct and/or indirect effects on glucose metabolism, successful HCV treatment may have an impact in reducing glucose level, pre-diabetes, the need of treatment for diabetes, and ultimately diabetes-associated morbidity. We investigated the association of DAA treatment and glucose metabolism in the context of development or resolution of hepatic fibrosis in a large cohort of HCV- infected patients.

Methods: In this retrospective single-center observational study, we investigated 281 patients receiving alloral DAA therapy for fasting plasma glucose, HbA1c, liver enzymes an  general clinical chemistry, measured during a 52-week follow-up. In addition, elastography, FIB-4- and APRI-calculation were used to assess hepatic fibrosis non-invasively.

Results: Successful elimination of HCV through DAA treatment was associated with a significant drop in fasting glucose level and a reduced rate of impaired fasting plasma glucose (FPG). Interestingly, this metabolic change was BMI-independent. In addition, long-term glucose levels also decreased after successful DAA treatment.A significant APRI-score reduction was associated with a persistent improvement of FPG. However, DAA did not have an impact on glucose metabolism in patients suffering from liver cirrhosis.

Conclusion: This study highlights the beneficial impact of successful HCV therapy on glucose metabolism and identifies patients with liver cirrhosis as a collective in need of intensified surveillance with regard to diabetes progression despite HCV eradication.
Sensitive response to ingestion of lipids in dyspepsia
Authors: Pop Lucian Liviu , Muresan Iulia Antonia
Published: September 2018

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A Blessed Endoscopy
Authors: Leal Tiago , Arroja Bruno , Gonçalves Raquel
Published: September 2018

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Spectroscopic Features of Raman Gain Profiles in Single-Mode Fibers Based on Silica Glass
Authors: Serdeha I. V. , Grygoruk V. I. , Felinskyi G. S.
Published: September 2018

The spectroscopic analysis of the frequency distribution of the amplification of optical radiation due to the Raman effect (Raman gain profile) in single-mode fibers based on silica glass has been carried out in the region of Stokes frequency shifts from 0 to 1400 cm−1. The Raman gain profiles are determined from the experimental spectra of spontaneous scattering for widespread fibers, namely for pure SiO2, GeO2, P2O5, and TiO2 doped fibers. The analytic expressions of the Raman gain profiles are given. They are obtained, by using the Gaussian decomposition by means of 11–12 modes, and the experimental profile is approximated with an accuracy of not less than 0.3%. The decomposition results are analyzed in terms of the fundamental oscillatory dynamics of molecular nanocomplexes in amorphous glass, as well as in the application aspect of the modeling of photonics devices. Examples of the proposed method applications are presented for the analysis of noise parameters of the fiber Raman amplifiers and for the generation bandwidth in fiber Raman lasers.
Mechanisms and Parameters of the Binding of Amitozinoberamid to DNA in the Aqueous Solution
Authors: Kutovyy S. Yu. , Savchuk R. S. , Bashmakova N. V. , Hovorun D. M. , Zaika L. A.
Published: September 2018

The interaction between the amitozinoberamid preparation (thiotepa-alkylated berberine) and a DNA macromolecule in the aqueous solution has been studied, by using the optical spectroscopy methods: electron absorption and fluorescence. The dependence of spectral characteristics on the concentration ratio N/c between the DNA base pairs and the ligand molecules is plotted. Using the system of modified Scatchard and McGhee–von Hippel equations, the parameters of the binding of amitozinoberamid to DNA are determined. A comparative analysis of the DNA interaction with amitozinoberamid, on the one hand, and berberine and sanguinarine alkaloids, on the other hand, is carried out. The structure and the spectra of electron absorption of thiotepa, berberine, and amitozinoberamid molecules are calculated in the framework of the density functional theory at the DFT B3LYP/6-31G(d,p) level.
Eye Findings in Infants With Suspected or Confirmed Antenatal Zika Virus Exposure
Authors: Tsui Irena , Moreira Maria Elisabeth Lopes , Rossetto Julia D. , Vasconcelos Zilton , Gaw Stephanie L. , Neves Luiza M. , Zin Olivia A. , Haefeli Lorena , Silveira Filho Joel Carlos Barros , Gomes Saint Clair , Adachi Kristina , Pone Marcos Vinicius da Silva , Pone Sheila Moura , Pereira Jose Paulo , Belfort Rubens , Arumugaswami Vaithilingaraja , Brasil Patricia , Nielsen-Saines Karin , Zin Andrea A.
Published: September 2018

OBJECTIVES:

To characterize ophthalmic manifestations of confirmed or suspected antenatal Zika virus (ZIKV) exposure.

METHODS:

Infants with antenatal ZIKV exposure were referred for evaluation during the 2015–2016 Rio de Janeiro outbreak. Mothers with symptomatic ZIKV infection during pregnancy and/or infants with microcephaly or other findings that were suggestive of suspected antenatal exposure were tested with reverse transcriptase polymerase chain reaction (RT-PCR). Complete eye examinations were performed by pediatric ophthalmologists between January 2016 and February 2017. The main outcome measure was eye abnormalities in RT-PCR–positive and suspected (ie, not tested or RT-PCR–negative) antenatal ZIKV cases.

RESULTS:

Of 224 infants, 189 had RT-PCR testing performed. Of 189 patients, 156 had positive RT-PCR results in their blood, urine, and/or placenta. Of 224 infants, 90 had central nervous system (CNS) abnormalities, including microcephaly (62 infants). Eye abnormalities were present in 57 of 224 (25.4%) infants. Optic nerve (44 of 57; 77.2%) and retina abnormalities (37 of 57; 64.9%) were the most common. The group with suspected ZIKV infection (68 infants) had proportionally more eye (36.8% vs 20.5%; P = .022) and CNS abnormalities (68.3% vs 28.1%; P = .008), likely because of referral patterns. Eye abnormalities consistent with ZIKV infection were clinically comparable in both RT-PCR–positive and unconfirmed groups, including 4 RT-PCR–positive infants of 5 without any CNS abnormalities.

CONCLUSIONS:

Similar eye manifestations were identified regardless of laboratory confirmation. Well-appearing infants were also found to have eye abnormalities. Therefore, all infants born after ZIKV outbreaks should be universally screened for eye abnormalities.
EFFECT OF SOME ADDITIVES ON PROCESSBILITY, MECHANICAL PROPERTIES AND MORPHOLOGY OF POLYOXYMETHYLENE/SILICA NANOCOMPOSITES
Authors: Nguyen Chinh Thuy , Thai Hoang , Tran Mai Thi
Published: September 2018

Using additives for polyoxymethylene/silica (POM/SiO2) nanocomposite system is one of suitable solutions to improve processbility, mechanical properties, especially, elongation at break of the material. In this paper, the effect of some additives on the processbility, mechanical properties and morphology of polyoxymethylene/silica (POM/SiO2) nanocomposite was investigated. Zinc stearate (under the commercial name ultraflow – UTF), ethylene-vinyl acetate copolymer (EVA), linear low density polyethylene (LLDPE) and polylactic acid grafted 5 wt.% of polyethylene glycol (PELA) were used as additives for the nanocomposites. The obtained results showed that the preparing process of the POM/SiO2 nanocomposite becam more easily in the presence of PELA, UTF and EVA, corresponding to a lower torque and mixing energy. The PELA caused decrease in the E-modulus or hardness and increase in elongation at break as well as tensile strength of the POM/SiO2 nanocomposites. The SEM images showed that POM and  nanosilica were less compatible in the  nanocomposite using EVA, LLDPE and UTF and they were more compatible with using PELA.
SYNTHESIS OF PHENOTHIAZINE DERIVATIVES AS NOVEL MOIETIES TOWARD UTILIZATION IN ALTERNATIVE DONOR – ACCEPTOR CONJUGATED POLYMERS
Authors: Truong Khuong Tung , Nguyen Ha Tran , Le Kien Anh
Published: September 2018

Two new phenothiazine – based structures, including 4-(10H-phenothiazin-10-yl)-N,N-diphenylaniline (PDA) and 10-(pyren-1-yl)-10H-phenothiazine (PyP) were synthesized via Buchwald-Hartwig C-N coupling amination using catalytic palladium modulated by electron-rich ligands. Chemical structures were analysed via proton nuclear magnetic resonance (1H NMR) spectroscopy. Then, photo-properties were characterized by UV – Vis absorption spectroscopy in various concentrations of each product. The results showed that PDA and PyP are highly potential donor units for well-performed donor – acceptor conjugated polymers.
SYNTHESIS OF COPPER-BASED NANOPARTICLE CATALYSTS BY DIFFERENT METHODS FOR TOTAL OXIDATION OF VOC
Authors: Le Toan Minh , Than Quoc An Ha , Pham Huu Thien
Published: September 2018

In this paper, the process of preparing 10 wt.% Cu/g-Al2O3 catalysts was studied by different methods. The changes in structure and texture of the catalysts were examined by X-ray diffraction (XRD), transmission electron microscopy (TEM) and Fourier-transform infrared spectroscopy (FT-IR). The activities of catalyst were investigated completely oxidized VOC (toluene and n-butanol) on gas-phase reactions over the Cu/g-Al2O3 catalyst. The results were found that influence of the size of copper nanoparticles enhancing copper dispersion and selectivity of the catalyst prepared by non-thermal plasma (NTP) was superior to those obtained from the impregnation (WI) and deposition-precipitation (DP). The total oxidation of VOC to CO2 and H2O was achieved above 275oC. Compared to the WI and DP, the NTP method increased the oxidation efficiency by 15-30%.
SYNTHESIS OF EVAgMA AND ITS EFFECTS ON TENSILE PROPERTIES AND MORPHOLOGY OF ETHYLENE VINYL ACETATE COPOLYMER/BAMBOO FLOUR AND POLYPROPYLENE/ BAMBOO FLOUR COMPOSITES
Authors: Huynh Mai Duc , Tham Do Quang , Cong Do Van , Trung Tran Huu , Giang Nguyen Vu
Published: September 2018

Thermoplastic composites reinforced with natural fillers (WPCs) have being attracted many attentions in recent years. The biggest challenges for WPCs production have to face is the poor adhesion and interaction between the components in the composites. This study investigates the technique to overcome these challenges without the treatment and surface modification of natural additive fillers. The obtained experimental results showed that using maleic anhydride grafted ethylene vinyl acetate copolymer (EVAgMA) with 1.16 wt.% of MA could enhance the adhesion and interaction of bamboo flour (BF) with EVA and polypropylene (PP) matrices. These expressed through the improvement of tensile properties and mophological structure of EVA/BF composite and PP/BF composite with the presence of EVAgMA. Tensile strength of EVA/BF and PP/BF composites at the same 50 wt% of BF, increased 67 and 12%, respectively when EVAgMA was introduced.
PROPERTIES OF COMPOSITE BASED ON HIGH DENSITY POLYETHYLENE/ETHYLENE VINYL ACETATE BLEND AND A NOVEL ORGANIC MODIFIED WASTE GYPSUM
Authors: Huu Trung Tran , Huynh Mai Duc , Cong Do Van , Giang Nguyen Vu
Published: September 2018

In this study, waste gypsum (WGS) was used as the filler in blend of high density polyethylene (HDPE) and ethylene vinyl acetate copolymer (EVA) in order to improve the flame resistance of this composite. After modification by ethylene bis stearamide (EBS), modified gypsum (EGS) at various contents was dispersed into HDPE/EVA blend by melt-mixing method to obtain EGS/HDPE/EVA composites. The IR analysis of the EGS showed the interaction between EBS and gypsum. The difference in morphology of HDPE/EVA/EGS and HDPE/EVA/OGS composites was also observed in SEM images. By adding EGS and small amounts of flame retardant additives such as ammonia polyphosphate and zinc borate, the thermal stability and the flame resistance of HDPE/EVA/EGS composites have improved and classified at V2 grade of UL94 standard. Moreover, the second self extinguishing time (t2) of EGS composite is shorter than that of unmodified gypsum (OGS) composite because of the quality char forming after the fist burning and it plays a role as thermal barriers to protect material from heat of the second ignition. About mechanical properties, both tensile strength and elongation at break of the composite decreased with increasing the gypsum content and flame retardant additives because of filler aggregation.
Reduzindo o “gap” entre a proposta de ensino e a estrutura cognitiva dos estudantes
Authors: Cardoso Moacyr Machado
Published: September 2018

O presente trabalho buscou analisar a representação social que um grupo de estudantes universitários têm a respeito da temática “gestão de riscos ambientais” e compará-la a uma estratégia elaborada para ministrar o tema, que é a construção do mapa conceitual. Esta comparação propicia a redução do “gap” entre o que é proposto e o que os estudantes está pronto a assimilar. Foram utilizadas várias ferramentas para análise de evocações de palavras e de análise textual, tais como gráfico de similaridade, classificação hierárquica descendente, dentre outras. Finalmente pôde-se concluir que o mapa conceitual pode ser aperfeiçoado a partir da análise da representação social que os alunos têm a respeito da temática.
A importância da gestão de stakeholders em obras públicas: um estudo de caso sobre a ciclo faixa da cidade de São Paulo
Authors: Bertholdo Larissa , De Nadae Jeniffer , Do Vale João Walter Saunders Pacheco , Carvalho Marly Monteiro de
Published: September 2018

O progresso de um país está associado ao desenvolvimento das cidades, porém, a falta de planejamento implica em ter diversos problemas na realização dos projetos, como a gestão de stakeholders, que afetam parâmetros como tempo, custo e qualidade. As obras de infraestrutura utilizam verbas públicas, e objetivam promover a qualidade de vida. Comumente, a execução das políticas públicas, como a mobilidade urbana, deixa de ser eficaz para atender grupos ou não perder índices de popularidade. O objetivo deste artigo, foi identificar a importância da gestão dos stakeholders nos projetos de obras públicas, contextualizando a implementação das ciclo faixas na cidade de São Paulo, delimitando o foco desta implementação no bairro de Higienópolis. Como orientação para o estudo de caso, buscou-se o referencial teórico inerentes ao tema, realização de pesquisa documental e as entrevistas com comerciantes foram realizadas no bairro de Higienópolis, zona oeste da cidade de São Paulo-SP e a Companhia de Engenharia de Tráfego de São Paulo. Constatou-se que a ausência da gestão dos stakeholders resultou na mobilização de um grupo de empresários para a contestação do traçado. Observou-se o envolvimento diferenciado dos órgãos públicos nas fases do projeto e com seus envolvidos, sendo assim, a verificação do seu sucesso varia de acordo com a opinião dos entrevistados.
Contribuições da teoria das restrições para a gestão da produção: aplicação em uma indústria de laticínios
Authors: Moura Débora Pinheiro Cacau , Machado Diego de Queiroz , Moreira Márcia Zabdiele , Araújo Carlos Manta Pinto de
Published: September 2018

Este estudo objetiva investigar as principais contribuições da aplicação da Teoria das Restrições (TOC) para a gestão da produção em uma indústria de laticínios de pequeno porte. Para isso, realizou-se um estudo de caso com abordagem qualitativa em uma indústria cearense de laticínios por meio da coleta de dados em documentos da empresa e observação direta no período de quatro meses. Com a aplicação do instrumento dos cinco passos de otimização contínua da TOC, foi possível identificar e explorar a principal restrição do sistema produtivo, sugerindo-se, em seguida, uma mudança no processo produtivo que permitiria não só a eliminação do recurso restritivo, mas também aumentaria a capacidade produtiva da linha de produção a qual a restrição se inseria.
Using the HAZOP procedure to assess a steam boiler safety system at a university hospital located in Brazil
Authors: Lucas de Oliveira Marcos , Ruppenthal Janis Elisa
Published: September 2018

The fierce competition between organizations has stimulated the production sector to improve its production processes simultaneously with the quality of its products, which, in short, heats up the economy and presents strong challenges to government agencies and employers, especially when considering the safety of employees in their workplace. The differential of this study is stated in the application of HAZOP in the boiler sector of a hospital, in other words, , in the micro industrial area ofa company that provides services In this context, this paper aims to identify the risks present in the fire-tube boilers of the University Hospital of Santa Maria, RS. The method used follows the application practices of the HAZOP tool. Therefore, on this basis, we proceeded with bibliographic analysis, methodologies, references, on-site visits at the university hospital, and studies of investments made in steam generators. Due to this study, it was possible to show that the industry under study has nooperation and maintenance default for the boiler, resulting in a high possibility of failure in the system as a whole and, in the case of an explosion, catastrophic consequences.
Multi-Institutional Survey of Fourth Year Students’ Self Assessed Milestone Based Skill Proficiency and Faculty Expectation During an Emergency Medicine Clerk-ship: Implications For Curriculum Development
Authors: Pettit Katie , Turner Joseph , Hogan Kathryn , Poznanski Stacey , Pfennig-Bass Camiron , Kouyoumjian Sarkis , Hexom Braden , Perkins Anthony , Pitre Cory , Humbert Aloysius
Published: September 2018

This article was migrated. The article was marked as recommended. Introduction: Emergency medicine milestones suggest skill performance expectations for graduating medical students. The objective of this study is to examine differences between student's perceived proficiency and faculty expectations relative to Level 1 EM milestones, identifying opportunities for curriculum development. Methods: Using ACGME milestone language, the authors developed a survey that measures student perceived skill proficiency with 22 skills, which was administered to fourth year medical students at 6 institutions. Similar surveys were sent to faculty to determine their expectations of students' skill proficiency. Differences between student and faculty responses were calculated. Results: There were 608 student and 114 faculty responses. There was a statistically significant difference between mean student and faculty responses for 13 of the 22 skills. For 10 of these skills, students rated their own skill proficiency higher than faculty expectations. For 3 of the skills, faculty rated their expectations higher than students' perceived proficiency. Conclusions: For pharmacology skills, student ratings were low, indicating an area to focus curriculum development. Items where student ratings are higher than faculty may be a result of overconfidence or a lack of understanding by faculty of students' abilities. Formal assessment of skills in these areas would help clarify the reason and direct faculty and curriculum development.
Sabit Endoparazit Nematodlarda Efektör Moleküller
Authors: DEVRAN Zübeyir
Published: September 2018

Bitki
paraziti nematodlar, gelişim ve üremeleri için gerekli olan besin maddelerini
elde edebilmek amacıyla konukçularıyla özel parazitik ilişkiler
geliştirmişlerdir. Günümüze kadar yaklaşık 4100 adet bitki parazit nematod türü
tanımlanmıştır. Sabit endoparazitik nematodlar içerisinden kök-ur nematodları (Meloidogyne spp.) ve kist nematodları (Globodera spp., ve Heterodera spp.) ekonomik olarak en zararlı bitki paraziti nematod
grupları olarak kabul edilmektedir. Sabit endoparazit nematodlar,
konukçularında özelleşmiş beslenme hücreleri oluşturmaktadırlar. Nematodlar
tarafından üretilen salgılar enfeksiyonda önemli rol oynamaktadırlar. Efektör
olarak adlandırılan bu salgılar birçok fonksiyona sahiptir. Bu derleme, sabit
endoparazitik nematodların efektör molekülleri hakkında bilgi vermek için
hazırlanmıştır.
Phenomenological Study on the “Me Too” Movement in the Tourism Industry
Authors:   The Tourism Sciences Society Of Korea, Han Jin-Seok , Kim Nam-Jo
Published: September 2018

The purpose of this study is to investigate workers' opinions about sexual harassment and sexual violence in the workplace considering the nature of the tourism industry. This study examined the actual situation of the “Me Too” movement in the tourism industry by applying the phenomenological approach. We have presented three research (individuals · tourism industry · society) questions. The results were grouped with the number of 202 semantic units, 25 modified semantic units, 11 sub-themes, and 4 themes. The meaning of this study is as follows. First, in carrying out research on sexual harassment and sexual violence, we introduced a social problem called the “Me Too” movement into the field of tourism. Second, we carried out research on various tourism industry workers and diversified the scope of research. Practical implications are that it has raised issues of sexual harassment and sexual violence in the tourism industry.
RELACIÓN ENTRE LA CALIDAD DE SERVICIOS ACADÉMICOS Y LA SATISFACCIÓN EN LOS ESTUDIANTES DE LA UNIVERSIDAD PERUANA UNIÓN FILIAL TARAPOTO – 2017
Authors: Arce Cobeñas Amado , Arana Rodríguez Maritsa
Published: September 2018

El propósito de esta investigación fue determinar el grado de relaciónque existe entre la calidad de servicios académicos y la satisfacciónen los estudiantes de la Universidad Peruana Unión –Filial Tarapoto,2017. El tipo de investigación fue descriptiva, explicativa, evaluativay propositiva con un diseño de investigación no experimental,correlacional de corte transversal. Estuvo conformada por 476estudiantes de la Facultad de Ciencias Empresariales y para obtener losresultados se utilizó dos instrumentos. Para medir la variable calidadde servicios académicos se utilizó el instrumento propuesto por Municio(2000), compuesto por 17 ítems y con una confiabilidad de alfa deCronbach 0.918, y para la variable satisfacción se utilizó el instrumentopropuesto por Gento y Vivas (2003) compuesta por 77 ítems y con unaconfiabilidad de alfa de Cronbach 0.891. Los resultados muestran queexiste una relación directa significativa (
ANÁLISIS DE FACTORES INTERVINIENTES RELACIONADOS AL MODELO DEUNIVERSIDADES EMPRENDEDORAS EN SUDAMÉRICA
Authors: Aguilera Vargas Anselmo , Paredes Aguirre Alfonso
Published: September 2018

Esta investigación analiza los factores de desarrollo externos, de organización interna y mecanismos de apoyo al emprendimiento que traen como resultado una universidad emprendedora en instituciones Sudamericanas. Es de tipo cuantitativo, correlacional y de carácter explicativo con diseño de variables que busca conocer en qué medida éstas pueden ser predictoras de un modelo de universidades emprendedoras. La muestra correspondió a 65 universidades pertenecientes a 8 países sudamericanos con un carácter no probabilístico, cuyos datos fueron recolectados por encuestas online por los directores de ITT de las universidades seleccionadas. El modelo de Covin & Slevin, (1991) y adaptado para universidades por Markuerkiaga-Arritola, (2014) fue el utilizado en el estudio y consta de tres variables independientes que influyen sobre una variable dependiente calculándose el coeficiente de determinación de las variables para el contraste de las hipótesis, cuyos hallazgos muestran que se relacionan positiva y significativamente con los resultados obtenidos en universidades que implementan un modelo de gestión tipo universidad emprendedora. También se hizo un análisis SEM que permitió conocer el componente estructural relacionado con el tamaño de la muestra que fue significativo para el peso de las variables independientes sobre la dependiente, así como la covarianza entre ellas, así como los coeficientes de variables FAE y MAE que son directamente proporcionales con relación a la variable RUE. Finalmente, la dependencia geográfica, el estatus de dependencia y la pertenencia de un parque tecnológico mostraron diferencia estadística significativa para la gran mayoría de las dimensiones de las variables.