bluuebunny/crossref_metadata_2025 huggingface dataset:
INOVASI PRODUK ES KRIM SUSU KAMBING ETAWA-UBI UNGU
Authors: Ferichani Minar , Darsono Darsono , Supanggyo Supanggyo
Published: March 2018

This productive research about “The Producing of Ettawa Goat Milk-Sweet Purple Potato Ice Cream” aimed to create a product made from ettawa goat milk which is delicious, nutritious, enjoyable, and marketable. The research in corporation with ettawa goat livestock owner’s wives which is united as KUBE (Corporative Business Association) Adi Jaya at Sayegan Sub-District, Sleman District, Yogyakarta, also partner with Jomint Company, was done in 2011. Research included program socialization to KUBE Adi Jaya officials; producing to get advance product; laboratory test at Lab. of Food Technology and Agricultural Product, Faculty of Agricultural Engineering, Gadjah Mada University; product packaging; disseminating to women as members of KUBE Adi Jaya and neighborhood; measuring of satisfaction to the product; and marketing. Quality measurement was done to measure satisfaction to product consisted of 4 indicators, those were taste, appearance, packaging, and contents (nutrition ingredient). The formula that was used was S = P/E which was a comparison among the expecting product (E) and the fact of product/product performance (P), in this case about how product showed the performance as real to compete with E. This formula was a modified concept by Kotler that states S = f(E,P). The criteria which was used was if S or Sav ≥ 1, it mean the product had high level of satisfaction; moderate if 0.7 < x < 1; and low if ≤ 0.7. Competitor product as E was an establish product, it was Walls ice cream as a product which was produced by Unilever Company, and our advance product as P. The research results show that the product contents complete nutrition. Contents of Cvitamin, protein and fiber function to protect and increase consumer’s healthy. Product also contents carotene, antioxidant and antocyanin that function to prevent cancer and cell degenerative process. Based on perspective about contents, the product is “ready” to be competed with ice cream which has established. The highest value of Sav is gained on contents (1,24), followed appearance (0,997), taste (0,983), and packaging (0,974). Level of respondent satisfaction to contents of etawa goat milk – sweet purple potato ice cream included high caused > 1, while to three others elements included moderate-high caused close to 1. Totally, Sav value that is achieved is 1.038, it means the product can satisfy the consumers in high level caused > 1. The product has capacity to compete even more satisfy than Walls ice cream based on product perspective (element of marketing mix). The product gets positive responses from members of KUBE Adi Jaya and others dissemination participants, also shops as partners of Jomint.
STRATEGI PEMERINTAH KABUPATEN WONOGIRI DALAM MENGEMBANGKAN SENTRA AGROINDUSTRI BREM PUTIH
Authors: Harisudin Mohamad , Wijianto Arip , Widiyanto Widiyanto
Published: March 2018

This study aims to analyze condition of white brem agroindustrial center inWonogiri, Identifying internal and external environmental conditions, Determiningalternative strategies and priorities determining the most appropriate strategy appliedWonogiri Government in developing agro-industry white brem centers. This study is adescriptive analytical study using primary and secondary data. Primary data to explain thewhite brem conditions agroindustry, strategic factors and alternative strategies anddetermination of the strategy through surveys, observation and focus group discussion.Secondary data in the form of monographs and the potential economic data in Wonogiriregency. Tools Analysis used is the SWOT matrix and the matrix QSP. The studyconcluded that the centers of agroindustrial white brem in Wonogiri is the average revenuein May 2011 amounted to Rp 17,634,375, -; cost needed is Rp 16,103,678, - and therevenue of Rp 1,530,697, -. Strength strategic factors are ease of exchanging information,ease of making sales of products, experience and skills sought a long labor. Strategicfactors are drawbacks: The employers are less innovative, less promotional efforts, piecesof white brem uninteresting, unattractive packaging, the center has not been managed well,the strategic factor market opportunities is a high demand, the development of servicesuppliers of raw materials, the presence of community agencies (bakul), alignments ofgovernment policies, developments in food processing technology, development ofinformation technology. Strategic factor is the threat of price fluctuations of raw materials,competitors' similar product innovation, the presence of product substitution, governmentpolicies that are less integrated, bright sun /weather. Priority strategies are recommended sothat the development of agro-industry centers in the white brem Wonogiri can runeffectively is to Improve togetherness among employers to boost innovation in order toincrease profits.
UPAYA PERBAIKAN STATUS KESUBURAN LAHAN SAWAH TERDEGRADASI DENGAN PENAMBAHAN BAHAN ORGANIK
Authors: Minardi Slamet , Hartati Sri , Pardono Pardono
Published: March 2018

N/A
EFEKTIVITAS JENIS POLINATOR DAN ASUPAN HARA TERHADAP HASIL BIJI DAN UMBI BAWANG MERAH (Alium Cepa L. 1)
Authors: Notosandjojo Yv Pardjo , Sulandjari Sulandjari
Published: March 2018

N/A
EFEKTIVITAS MODEL PEMBELAJARAN CONTEXTUAL TEACHING AND LEARNING (CTL) DAN BERBASIS E-LEARNING EDMODO TERHADAP HASIL BELAJAR SISWA PADA MATERI LANGKAH PENELITIAN GEOGRAFI DI KELAS X IPS SMA DAN MA ASSALAAM SUKOHARJO
Authors: Mardliyana Erna , Muryani Chatarina , Sarwono Sarwono
Published: March 2018

The purpose of this research is to know: (1) the difference of geography learning outcomes between using Contextual Teaching and Learning (CTL), Edmodo based on e-learning, and conventional learning model (2) the difference of geography learning outcomes between using Contextual Teaching and Learning (CTL) learning model and Edmodo based on e-learning model; (3) the difference of geography learning outcomes between using Contextual Teaching and Learning (CTL) learning model and conventional learning model; (4) the difference of geography learning outcomes between using Edmodo based on e-learning and conventional learning model on geography research step at X IPS SMA and MA Assalaam Sukoharjo. The technique ofcollecting data uses written tests in the form of multiple choice questions. The data validity uses the validity of the questionsto measure the difference, level of difficult, and reability. For the normality testing uses liliefors method, meanwhile the data analysis uses one way anava. The results of this research are: (1) There is a significant difference of geography learning outcomes between using Contextual Teaching and Learning (CTL) learning model, e-learning based on edmodo and conventional learning model; (2) There is not difference in geography learning outcomes between using Contextual Teaching and Learning (CTL) learning model and e-learning model of edmodo(both of models are equally effective); (3) the result of geography study using Contextual Teaching and Learning (CTL) learning model is better than conventional learning model; (4) the result of geography study using e-learning model of edmodo is better than conventional learning model on the research step of geography at class X IPS SMA and MA Assalaam Sukoharjo.
Keywords: CTL Learning Model, Edmodo Based E-learning, Geography Learning Outcomes of Geography Material.
STUDI AGIHAN SALINITAS AIRTANAH DANGKAL DI KECAMATAN PURING KABUPATEN KEBUMEN TAHUN 2016
Authors: Fatoni Muhamad , Muryani Chatarina , Nugraha Setya
Published: March 2018

The purpose of this study is (1) Determine the spatial distribution of shallow groundwater salinity in Subdistrict Puring, District Kebumen 2016, (2) Knowing the public perception of the groundwater condition in the District Puring 2016, and (3) know the implementation of research results for high school geography learning material grade X curriculum 2013
This study used a qualitative method with a spatial approach. The technique of taking research subjects in this study using Transect Line Plots. The technique of collecting data using interviews, observation and analysis of secondary data. Analysis of the data in this study using the analysis of matching, and scoring.
The results showed that: (1) Spatial Distribution shallow groundwater salinity in the Subdistrict Puring concentrated in the south or near the beach, it means getting closer to the sea, the higher salinity value. (2) The public perception of the condition of groundwater in the Subdistrict Puring, included in the medium classification, it's means that people have started to know if they are a potential area groundwater in their wells polluted and have a fairly high salinity values. (3) Implementation of the results of this study are presented in the form of learning modules Geography class X High School Curriculum 2013, which contains material on groundwater and salinity. Keywords: salinity, public perception, groundwater
Assessing the Breeding Potential of Extra‐Long Staple Upland Germplasm in a Cotton Breeding Program
Authors: Campbell B.T. , Hugie K.L. , Wu J. , Jones D.C.
Published: March 2018

Fiber quality improvement of upland cotton (Gossypium hirsutum L.) is essential to increase the value and competitiveness of cotton fiber. The closely related allotetraploid species G. barbadense L. has long been targeted as a source of beneficial fiber quality alleles. Although interspecific hybridization between G. hirsutum and G. barbadense results in fertile offspring, cultivar development programs have seen little success using this approach. In this study, we evaluated the breeding potential of extra‐long staple (ELS) upland accessions that presumably contain G. barbadense introgressions. As expected, ELS upland accessions produced long fibers with overall excellent mean fiber quality performance. Genetic effects indicated that ELS upland accessions transmitted both additive and nonadditive beneficial alleles for fiber length and micronaire. However, ELS upland accessions also transmitted negative effects for lint percentage, lint yield, and fiber strength. Results suggest that ELS upland accessions are a good source for improving fiber length but also support the idea that linkage drag and skewed chromatin transmission, often seen in progeny derived from interspecific hybridization, may still proliferate in offspring derived from ELS upland accessions.
Maintaining the Accuracy of Genomewide Predictions when Selection Has Occurred in the Training Population
Authors: Brandariz Sofía P. , Bernardo Rex
Published: March 2018

Routine genomewide selection in maize (Zea mays L.) will lead to phenotyping only a subset of the lines in a biparental population between inbreds A and B. If the cross is used as part of the training population for predicting the performance of lines in a future cross, the training population would be a selected rather than a random subset of lines. Our objective was to determine if selection in the training population (i) reduces the response to selection and accuracy of genomewide selection in a biparental (A/B) population, and (ii) increases the genetic similarity of the best lines in the A/B population. A total of 969 biparental maize populations were evaluated at 4 to 12 environments from 2000 to 2008 for grain yield, moisture, and test weight. The parents of the 969 populations were genotyped with 2911 single nucleotide polymorphism (SNP) markers, and marker data were imputed from lower‐density screening of the progeny in each biparental cross. Having phenotypic information on only a selected fraction (25%) of the lines significantly reduced the response to selection and predictive ability. However, augmenting the training set with the five poorest lines nearly restored the predictions to their original level of accuracy. Prior selection in the training population did not increase the genetic similarity (calculated from nonimputed SNP data) of the best lines in the A/B population. We concluded that including a small number of the poorest lines in a training population is a practical way to maintain the effectiveness of genomewide selection.
Soil Phospholipid Fatty Acid Biomarkers and β‐Glucosidase Activities after Long‐Term Manure and Fertilizer N Applications
Authors: Lupwayi Newton Z. , Kanashiro Derrick A. , Eastman Andrea H. , Hao Xiying
Published: March 2018

Core Ideas

Thirty‐five annual manure applications increased soil microbial biomass and activity.

Responses occurred mostly in the top 15 cm of soil, with some in the 15‐ to 30‐cm depth

The three times recommended application rate had some microbial responses down to 60 cm of soil.

Twenty annual fertilizer N applications did not affect soil microbial properties.

The microbial properties were positively related to soil organic C.

Manure applications to soil usually increase soil microbial properties, but their vertical distribution is rarely evaluated. Soil phospholipid fatty acid (PLFA) biomarkers and β‐glucosidase activity were measured down to the 120‐ cm depth in a trial that had received annual manure or N fertilizer applications for 37 or 20 yr, respectively. The manure application rates were 0, 60, 120, and 180 Mg ha–1, representing 0×, 1×, 2×, and 3× the recommended rates. The effect of N fertilizer at 100 kg N ha–1 was compared with that of manure at 60 Mg ha–1. Total PLFAs at 60 Mg ha–1 manure rate were 3.2× those of the control, and β‐glucosidase activity 1.9× to 2.4×, but fertilizer N had no effects on soil microbial PLFAs or enzyme activity. These manure effects occurred mostly in the 0‐ to 15‐cm soil depth, with smaller effects in the 15‐ to 30‐cm depth. Increasing manure rate to 180 Mg ha–1 also increased total PLFAs linearly, but quadratic increases were observed for β‐glucosidase activity. The vertical distribution of the responses at 120 Mg ha–1 was similar to that at 60 Mg ha–1; however the 180 Mg ha–1 rate shifted some responses down to the 30‐ to 60‐cm soil depth. These PLFA contents and enzyme activities were positively correlated with soil organic C, total N, and available P. Therefore, manure improved the biological quality of mostly the top 15 cm of soil, but down to 30 or 60 cm for the high manure rates, by increasing microbial biomass and activity, but N fertilizer had no effects.
IT Security In The Higher Education Institutions
Authors: Marcial Dave E.
Published: March 2018

This paper investigates the level of prioritization and degree of implementation of IT security in higher education institutions (HEIs) in the Philippines. A total of 95 HEIs in the Philippines were evaluated in the study. The study reveals that the level of prioritization of IT security in the Philippines HEIs is high. This signifies that IT security is prioritized and there is need to be done in the next 3 years in these HEIs. The degree of implementation of IT security in the HEIs is moderately implemented indicating that although this component is in the strategic plan of the HEIs, little or no action has been undertaken in this regard. The study further reveals that the level of prioritization of IT security has a significant correlation at 0.01 level of confidence with the degree of implementation of IT security in the HEIs in the Philippines. Keywords : security, privacy, risk, IT in education
IMPLEMENTASI ALGORITMA FRAKTAL UNTUK KOMPRESI CITRA DENGAN METODE PENCARIAN LOKAL
Authors: Jatmika Jatmika , Randongkir Tresia F
Published: March 2018

The nature of image compression methods always fall between lossy and lossless compression. Lossy compression eliminates insignificant information while retaining the perception, while lossless compression retains the original data completely. These recent years saw the rise of Fractal Image Compression (FIC), a new lossy image compression algorithm. This algorithm features a self-similarity, which in other word it regards an image as an arrangement of copied parts of the image itself, thus we only need a composition of transformation to code an image. This paper discuss about how fractal algorithm can be applied for image compression, how Fractal Image Compression works, and how to implement it using local search where comparison is done to the nearest area (segments) only. Searching in progress often involves great amount of data which takes a considerable time. Local search can reduce the time by comparing only the nearest area within the neighbourhood of the current block, which in turn shortened the overall processing time. However, the sharply reduced processing time achieved by localizing the search does not drastically reduce the quality of the output time.
IMPLEMENTASI DYNAMIC PROGRAMMING PADA PENENTUAN JENIS MATERIAL UTAMA BANGUNAN ARENA FUTSAL
Authors: Anthony Andree , Santosa R. Gunawan , Lukito Yuan
Published: March 2018

Building futsal court need some planning, especially about the materials needed to build a futsal court such as synthetic grass, roofs, walls, benches, and some other materials. Each of materials have many choices usually based on quality and price. Thus it needs a system to assist on calculating the optimum materials combination based on a specified budget. Minimax Route method are used with dynamic programming techniques to maximize the quality of materials while minimizing the price of materials chosen. Based on system testing conducted to futsal court owners in Yogyakarta, the implementation are helpful and have many useful information for someone who want to build futsal court.
IMPLEMENTASI ALGORITMA FP-GROWTH UNTUK SISTEM REKOMENDASI BUKU DI PERPUSTAKAAN UKDW
Authors: Miraldi Rama Novta , Christanto Antonius Rachmat , Susanto Budi
Published: March 2018

The number of collections in a library will be increase along with the growth of the library. The Library of Universitas Kristen Duta Wacana (UKDW) also has a large number-of books collection in order to provide literature and resources service to students. Wen the number of collection is very large, we need a retrieval system that will help anyone to find the needed resoLtrces. This system has a recommendation feature to provide related books or resources. This feature will help users to find similar literature/resources or related topic with what they need. This paper will describe about the main design and implementation of the book recommendation based on FP-Growth algorithm. Based on the experiments, this system can provide 60.78% of accuracy for related books recommendation.
IMPLEMENTASI FORWARD CHAINING UNTUK DIAGNOSA DEFISIENSI VITAMIN LARUT DALAM LEMAK BERBASISKAN WEB
Authors: Sevani Nina , Joshua Melvin
Published: March 2018

The growth of information technology is increasing lately. People can get the actual information from websites. The combination between website and expert system will help people to make an application that can think like an expert and spread it all around the world using the internet. The technology can be used to solve the availability problem of expert nutrient in Indonesia. The application was developed using forward chaining method as the inference system. It will make the application work like a nutrient expert, which asks the patient from general to specified symptoms. The knowledge based of the application was collected from trusted resources like nutrient experts and nutrient books. The application was tested by the nutrient expert. The result shows that the application can work properly like an expert.
IMPLEMENTASI MONTE CARLO TREE SEARCH PADA PERMAINAN KARTU “DAIFUGO”
Authors: Christian Eunike Thirza Hanitya , Santoso R. Gunawan , Purwanto Erick
Published: March 2018

Daifugo is climbing card game that is originated from Japan. AI player of Daifugo card game can be implemented using Monte Carlo Tree Search to get optimal result from random simulation. Monte Carlo Tree Search has 4 step, selection, expansion, simulation and backpropagation that is executed until maximal loop is reached. Objective of using Monte Carlo Tree Search on AI player in Daifugo card game is to get move with high winning rate and to observe the effect of number of loop on the method to winning rate
IMPLEMENTASI PERMAINAN FLOW PADA PEMBANGUNAN SISTEM CAPTCHA
Authors: Setiawan Indra , Raharjo Willy Sudiarto , Susanto Budi
Published: March 2018

The basic challenge in designing an obfuscating CAPTCHAs is to make them easy enough that users are not dissuaded from attempting a solution, yet still too difficult to solve using available image-based computer vision algorithms. CAPTCHA has been widely used in many web applications and there has been so many research on CAPTCHA. Current technology enables computer to easily solve image-based CAPTCHA with high probability, so we propose another type of CAPTCHA-based authenticaton that can not be solved by utilizing Optical Character Recognition but still easy to use for new users. We implemented the new model of CAPTCHA using FLOW game. We found that the success rate of this new system is 92.025%, completion time is 6.3614s, and 81,67% of users are able to solve it in less than 10s.
IMPLEMENTASI METODE CHAIN CODE UNTUK PENGENALAN RAMBU LALU LINTAS
Authors: Agustian Ryan , H. Nugroho Agus , Karel Junius
Published: March 2018

Traffic sign is needed to give information to users so they can be aware in roads. There are many types of traffic signs and each has many forms and different from each other so users sometimes have difficuty in recognizing traffic signs. In this research, the signs used are signs based on Peraturan Menteri Perhubungan Republik Indonesia Nomor PM 13 Tahun 2014. Modified Chain Code method was implemented for feature extraction process and Euclidean Distance method is used to calculating the similarity. Testing is done with 5 types of tests i.e. resize image, objects truncated, added a few objects to image, added many objects to image and noise spots. The test results showed the accuracy of the image of traffic signs to be recognized is 92.5%.
Managerial decisions and accounting performance following mergers in Greece
Authors: Pantelidis Panagiotis , Pazarskis Michail , Drogalas George , Zezou Stavroula
Published: March 2018

An investigation was conducted to study a sample of 23 Greek firms listed on the Athens Stock Exchange that underwent mergers from 2011 to 2015, which is a period that embodies the Greek economic crisis. For the investigation, the authors use statistical tests to explore relative changes at twenty accounting ratios of the sample firms. These ratios are computed for one year before and after the merger. These ratios are found to be statistically insignificant indicating firms do not experience a post-merger improvement in accounting performance. The authors also examine six qualitative variables representing merger characteristics as past managerial decisions. Important findings for these characteristics include the following. First, for companies that do not fall under the same production line, the researchers observe an improvement for three ratios: collection period ratio, return on total assets, and profit or loss before tax. Thus, liquidity and profitability are improved. Second, when companies merged with their subsidiaries, the authors discover significant improvement for two ratios: gross margin and collection period ratio. In brief, positive results are found for mergers with subsidiaries and negative results with others. Third, the payment method influences two ratios, the current ratio and the stock turnover ratio. The current ratio is affected positively for the transactions in cash and negatively for the transactions in shares, while the stock turnover ratio is affected negatively for cash transactions and positively for share transactions.
The Aspects of Efficient Dynamic Configurations in Architecture
Authors: Mohamed Randa Hassan , Ebrahim Gehan Ahmed
Published: March 2018

The elements and means affecting the formulation and structure of the architectural buildings have been greatly developed by man throughout different ages according to the development of technology, so the dimensions and specifications of configuring dynamic buildings can be designed and controlled in order to leave the required effects on the environment and the user to serve certain purpose or function. But it seems that the process of formulating any architectural vocabulary acting on the dynamic aspect goes beyond the boundaries of the perceived dimensions and the included unperceived one; as the first dimensions may be considered namely the aesthetic aspect in architectural work, while the included unperceived dimensions may display efficiency in work which is greatly influenced by the personality and the formative attitudes of the architect, the site style and the surrounded environment, as well as the economic efficiency of the building. However, the liability issue seems to be the absence of the criterion of forming efficient dynamic configurations in architecture. Accordingly this research aims to reach this criterion as identifying the architectural attitudes; as a decisive in shaping the building as its facades, envelopes, sections or plans. Additionally, it attempts to explain the reciprocal relation between the architectural vocabulary (perceived aspects of configuration) and the unperceived one which is distinguishing the valuable architectural works. The research will attempt to analyze the elements included and the aesthetic and formative considerations while configuring the dynamic building to determine the important role played by such formation in reaching the psychological and physiological effect on the user in turn to maximize its utilization of such architectural work.
Leveling the playing field for Metro Manila's impoverished households
Authors: Torio Philamer C.
Published: March 2018

Metro Manila's water privatization is one of the world's largest and longest-running privatization programs for a water utility. While traditional efficiency metrics show significantly improved service levels under this schema, local anti-privatization activists maintain that the program does not benefit the urban poor. Assessments from an equity lens offer a fresh perspective, using information from a consumer survey of 53,733 residential households, privatization reports, and field interviews. Results show that access and affordability remain critical concerns for impoverished urban households despite major service improvements. Philippine policy makers must address these twin concerns in order to ensure a level playing field for these vulnerable households.
Long-term operation of a novel electrically-enhanced biomass concentrator reactor for wastewater treatment
Authors: Cecconet D. , Callegari A. , Capodaglio A. G.
Published: March 2018

Membrane biological reactors (MBRs) are a key technology in wastewater treatment nowadays. However, due to their high construction cost and energetic requirements, alternatives based on the same principle of biomass retention have been designed and operated. Amongst these, biomass concentrator reactors (BCRs), using a coarser filter medium instead of a membrane, have shown to be able to remove a wide range of contaminants from wastewater and groundwater. A new BCR-derived technology enhanced with an electric field, called the electrically-enhanced biomass concentrator reactor (E2BCR), was designed and tested for urban wastewater treatment at different organic loads for a period of 180 days. The electrically-enhanced reactor showed better chemical oxygen demand (COD) removal performances than a non-enhanced control reactor (92.4% and 83.6% respectively) thanks also to electrocoagulation effects, and a lower fouling tendency, and proved to be more energy efficient in comparison with the control reactor in terms of energy consumption per mass of COD removed.
Treatment Considerations for Pulmonary Arterial Hypertension and Assessment of Treatment Response
Authors: Frantz Robert P.
Published: March 2018

The process of considering initial treatment options for a patient with pulmonary arterial hypertension (PAH), implementing that treatment, and reassessing response can be conceived as a 7-step process. A patient-centered approach, conducted in the context of a pulmonary hypertension care team, implements these steps in a thoughtful and well-organized fashion.Step 1: Perform a thorough diagnostic evaluationStep 2: Consider patient PAH classification and comorbiditiesStep 3: Assess risk profileStep 4: Develop a nuanced understanding of patient goals and preferencesStep 5: Create an initial treatment strategyStep 6: Implement a proactive longitudinal follow-up care planStep 7: Adjust treatment approach based on clear metrics of effectiveness and tolerability

The burgeoning array of treatment options for PAH provides the opportunity to tailor therapy to the needs of individual patients, but also demands that the clinician develop a cogent strategy for initiating therapy, monitoring therapeutic response, and addressing side effects of therapy. In this review, we seek to provide a practical framework for approaching this challenge.
Ischemic Stroke and Kynurenines: Medicinal Chemistry Aspects
Authors: Hertelendy Péter , Toldi József , Fülöp Ferenc , Vécsei László
Published: March 2018

Ischemic stroke is one of the leading causes of mortality and permanent disability in developed
countries. Stroke induces massive glutamate release, which in turn causes N-Methyl-D-aspartate (NMDA)
receptor over-excitation and thus, calcium overload in neurons leading to cell death via apoptotic cascades.
The kynurenine pathway is a complex enzymatic cascade of tryptophan catabolism, generating
various neuroactive metabolites. One metabolite, kynurenic acid (KYNA), is a potent endogenous NMDA
glutamate receptor antagonist, making it a possible therapeutic tool to decrease excitotoxicity and neuroinflammation.
Recently, clinical investigations have shown that during the acute phase of ischemic stroke,
kynurenine pathway is activated and peripheral levels of metabolites correlated with worse outcome. In
this review, we set out to summarize the current literature on the connection of the kynurenine pathway
and ischemic stroke and set a course for future investigations and potential drug development.
Platelet-Derived Exosomes Affect the Proliferation and Migration of Human Umbilical Vein Endothelial Cells Via miR-126
Authors: Sun Yan , Liu Xiao-li , Zhang Dai , Liu Fang , Cheng Yu-jing , Ma Yue , Zhou Yu-jie , Zhao Ying-xin
Published: March 2018

Background:

Intraplaque angiogenesis, the process of generating new blood vessels mediated by endothelial cells, contributes to plaque growth, intraplaque hemorrhage, and thromboembolic events. Platelet-derived Exosomes (PLT-EXOs) affect angiogenesis in multiple ways. The ability of miR-126, one of the best-characterized miRNAs that regulates angiogenesis, carried by PLT-EXOs to influence angiogenesis via the regulation of the proliferation and migration of endothelial cells is unknown. In this study, we aimed to investigate the effects of PLT-EXOs on angiogenesis by Human Umbilical Vein Endothelial Cells (HUVECs).

Methods:

We evaluated the levels of miR-126 and angiogenic factors in PLT-EXOs from Acute Coronary Syndrome (ACS) patients and healthy donors by real-time Polymerase Chain Reaction (PCR) and western blotting. We incubated HUVECs with PLT-EXOs and measured cell proliferation and migration with the Cell Counting Kit-8 assay and scratch assay, respectively. We also investigated the expression of miR-126 and angiogenic factors in HUVECs after exposure to PLT-EXOs by western blotting and real-time PCR.

Results:

PLT-EXOs from ACS patients contained higher levels of miR-126 and angiogenic factors, including Vascular Endothelial Growth Factor (VEGF), basic Fibroblast Growth Factor (bFGF), and Transforming Growth Factor Beta 1 (TGF-β1), than those from healthy donors (p<0.05). Moreover, the levels of exosomal miR-126 and angiogenic factors were increased after stimulation with thrombin (p<0.01). HUVEC proliferation and migration were promoted by treatment with activated PLT-EXOs (p<0.01); they were accompanied by the over-expression of miR-126 and angiogenic factors, including VEGF, bFGF, and TGF-β1 (p<0.01).

Conclusion:

Activated PLT-EXOs promoted the proliferation and migration of HUVECs, and the overexpression of miR-126 and angiogenic factors, thereby elucidating potential new therapeutic targets for intraplaque angiogenesis.
Clinical Presentation, Quality of Care, Risk Factors and Outcomes in Women with Acute ST-Elevation Myocardial Infarction (STEMI): An Observational Report from Six Middle Eastern Countries
Authors: Shehab Abdulla , AlHabib Khalid F. , Bhagavathula Akshaya S. , Hersi Ahmad , Alfaleh Hussam , Alshamiri Mostafa Q. , Ullah Anhar , Sulaiman Khadim , Almahmeed Wael , Al Suwaidi Jassim , Alsheikh-Ali Alwai A. , Amin Haitham , Al Jarallah Mohammed , Salam Amar M.
Published: March 2018

Background:

Most of the available literature on ST-Elevated myocardial infarction (STEMI) in women was conducted in the developed world and data from Middle-East countries was limited.

Aims:

To examine the clinical presentation, patient management, quality of care, risk factors and inhospital outcomes of women with acute STEMI compared with men using data from a large STEMI registry from the Middle East.

Methods:

Data were derived from the third Gulf Registry of Acute Coronary Events (Gulf RACE-3Ps), a prospective, multinational study of adults with acute STEMI from 36 hospitals in 6 Middle-Eastern countries. The study included 2928 patients; 296 women (10.1%) and 2632 men (89.9%). Clinical presentations, management and in-hospital outcomes were compared between the 2 groups.

Results:

Women were 10 years older and more likely to have diabetes mellitus, hypertension, and hyperlipidemia compared with men who were more likely to be smokers (all p<0.001). Women had longer median symptom-onset to emergency department (ED) arrival times (230 vs. 170 min, p<0.001) and ED to diagnostic ECG (8 vs. 6 min., p<0.001). When primary percutaneous coronary intervention (PPCI) was performed, women had longer door-to-balloon time (DBT) (86 vs. 73 min., p=0.009). When thrombolytic therapy was not administered, women were less likely to receive PPCI (69.7 vs. 76.7%, p=0.036). The mean duration of hospital stay was longer in women (6.03 ± 22.51 vs. 3.41 ± 19.45 days, p=0.032) and the crude in-hospital mortality rate was higher in women (10.4 vs. 5.2%, p<0.001). However, after adjustments, multivariate analysis revealed a statistically non-significant trend of higher inhospital mortality among women than men (6.4 vs. 4.6%), (p=0.145).

Conclusion:

Our study demonstrates that women in our region have almost double the mortality from STEMI compared with men. Although this can partially be explained by older age and higher risk profiles in women, however, correction of identified gaps in quality of care should be attempted to reduce the high morbidity and mortality of STEMI in our women.
Voltammetric Sensors Based on Various Nanomaterials for the Determination of Sulfonamides
Authors: Beigizadeh Hana , Ganjali Mohammad Reza , Norouzi Parviz
Published: March 2018

Background:

The widespread applications of sulphonamides, as antibacterial or antimicrobial agents, and their mechanism of actions in the body, have changed their determination to an important issue in the area of human health.

Objective:

Here, history of developing voltammetric sensors based on nanomaterials for the detection of sulfonamides including sulfadiazine, sulfamethoxazole, sulfacetamide, sulfadimethoxine, sulfathiazole, sulfamethiazole and sulfamerazine is reviewed. Modified electrodes based on various nanomaterials (carbonaceous nanomaterials, Metallic Nanoparticles (MNPs), conducting nanopolymers) have been reported, and studies showed that nanomaterials have been mostly used to overcome problems like the poor sensitivity and selectivity of bare electrodes. The study covers the properties of each sensor in detail, and reports and compares the linear ranges, Limits of Detection (LODs), reproducibility, and reusability of the electrodes reported so far.
Apoptosis Caused by Triterpenes and Phytosterols and Antioxidant Activity of an Enriched Flavonoid Extract from Passiflora mucronata
Authors: da Silva Isabel C.V. , Kaluđerović Goran N. , de Oliveira Pollyana F. , Guimarães Denise O. , Quaresma Carla H. , Porzel Andrea , Muzitano Michelle F. , Wessjohann Ludger A. , Leal Ivana C.R.
Published: March 2018

Background:

P. mucronata (Pm) comes from South America, Brazil and is characterized as “Maracujá
de Restinga”. It is used in folk medicine for its soothing properties and in treating insomnia.

Objective:

The present study for the first time analyzed the antioxidant and cytotoxicity of the hydroalcoholic
leaves extract and fractions from Pm.

Method:

The cytotoxicity test will be evaluated by different assays (MTT and CV) against human prostate cancer
(PC3) and mouse malignant melanoma (B16F10) cell lines, and the antioxidant test by DPPH method.

Results:

β-Amyrin, oleanolic acid, β-sitosterol and stigmasterol were isolated of the most active, hexane fraction.
These substances were tested against the tumor cell lines: β-sitosterol and stigmasterol showed the most
relevant activity to PC3 in CV assay and, oleanolic acid to B16F10 by the MTT assay. In addition, it was possible
to indicate that the mode of cell death for stigmasterol, presumably is apoptosis. In terms of antioxidant
activity, the hydroalcoholic leaves extract presented higher activity (EC50 133.3 µg/mL) compared to the flower
(EC50 152.3 µg/mL) and fruit (EC50 207.9 µg/mL) extracts. By the HPLC-MS, it was possible to identify the
presence of flavones in the leaf extract (isoschaftoside, schaftoside, isovitexin, vitexin, isoorientin, orientin).

Conclusions:

P. mucronata hexane fraction showed promising cytotoxic effect against cancer cell lines, and
stigmasterol contributes to this activity, inducing apoptosis of these cells. Furthermore, as other Passiflora species,
Pm extract showed antioxidant activity and flavones are its major phenolic compounds.
Green Synthesis of Cobalt Oxide Nanoparticles by a Starch-Assisted Method
Authors: Vaya D. , Meena  , Das B.K.
Published: March 2018

Background:

The properties of the material are altered when material size shifted towards
nano-regime. This feature could be used for wastewater treatment process using model pollutant such as
dyes. Recently, nanoparticles are synthesized by a green chemical route using different capping agents.
This is the reason we adopt starch as green capping agent along with sol-gel method.

Objective:

To synthesize cobalt oxide nanoparticles by green chemical route and utilized it in degradation
of dyes.

Methods:

Synthesis of cobalt oxide nanoparticles by sol-gel method using starch as a capping agent.
The characteristics of surface modifications were investigated by UV-VIS, TEM, SEM, XRD and FTIR
techniques.

Results:

Cobalt oxide nanoparticles synthesized and inhibited photocatalytic activity.

Conclusion:

Deactivation of photocatalytic activity due to complex nature of starch. This property can
be used elsewhere as in light shielding applications to coat and protect surfaces in order to keep them
cool and safe from damage as in the painting of vehicles, roofs, buildings, water tanks, etc.
A Study on Financial Constraints of Capital Structure Theories and Dividend Policy: Evidence from Indian Capital Market
Authors: Sreenu Nenavath
Published: March 2018

The study focused on the ability of firms to play this role is in major part determined by the structure of the financial system in which they operate, and in particular whether this financial system is able to make capital available efficiently to those firms that need it. The study examines the relation between the Financing, Investments, Capital Budget and Dividend decisions, where the effect of financial constraints on the firm’s investment decision is investigated. The study focuses on how financial constraints affect different firms by investigating the extent to which the dependence on internal cash flow is affected by firm characteristics such as size, age, dividend payout ratio, and market listing. This implies that firms retain earnings (RE) in order to ensure that they have sufficient capital to invest, confirming the initial result that Indian firms are financially constrained. This study adopted a descriptive design that aims at exploring the financial constraints of dividend policy and capital structure theories of companies listed at NSE and BSE in India. The data was obtained from financial statements and balance sheet of all the listed companies’ information available at the NSE and BSE secretariat for 10 years from 2005 to 2015.
FRUITS AND VEGETABLES PRODUCTION AND ITS EFFECT ON CONSUMPTION WITH SPECIAL REFERENCE TO SELECT COUNTRIES
Authors: Musunuru Kamakshaiah , Venugopal R.
Published: March 2018

India is a land of agriculture diversity with 66 percent of its population still dependent on agriculture and contributing about 20 percent to the Indian GDP. Value addition of food products is expected to increase from 8 per cent to 35 per cent by 2025. Fresh Fruit and vegetable processing is also expected to increase from the current level of 2 per cent to 25 per cent of total production by 2025. This study is basically a secondary data analysis on certain international production and consumption of fruits and vegetables. The article deals with comparative study of certain select countries with respect to their fruits and vegetable production. The analysis shows that there is overwhelming evidence in support of the hypothesis that the study regions are significantly different in terms of their fruits and vegetable production and consumption but interestingly such differences are not able to help to group the countries with respect to fruits and vegetable production. There is also evidence in support of other hypothesis that the production and export level differences exists towards surplus.
As contribuições do movimento quilombola para a construção de uma proposta de educação específica
Authors: Moreira Agda Marina Ferreira , Brito José Eustáquio de
Published: March 2018

Os processos educativos e de formação político-identitários reproduzidos no interior de cada comunidade remanescente de quilombo, juntamente com as experiências advindas dos movimentos sociais quilombolas, são aspectos indispensáveis na discussão  de implementação de uma modalidade escolar quilombola. Partindo de um estudo de caso, apresentaremos resultados das observações oriundas da comunidade quilombola de Carrapatos da Tabatinga e do movimento quilombola mineiro, bem como da pesquisa de dissertação de mestrado em Educação e da trajetória profissional na ONG Cedefes e na N’Golo. Para tanto, utilizamos por método a observação participantes, além de trechos de entrevistas centradas no problema, realizadas no campo de pesquisa. Dentre os resultados apresentados, buscaremos enfatizar as formas de se educar construídas nas trocas cotidianas e nas interações com as mobilizações políticas, sendo ambas importantes produtoras de pedagogias próprias, que se relacionam diretamente às reinvindicações e aos aspectos tradicionais presentes nas comunidades quilombolas, sendo parte de uma cosmovisão africana. Em constante diálogo, comunidades e movimento nos instigam a reconhecer formas alternativas de formação de sujeitos engajados, que se reconhecem enquanto quilombolas e que são responsáveis diretos pela preservação dos saberes-fazeres construídos nos espaços de suas respectivas comunidades.
APRESENTAÇÃO
Authors: Messeder Marcos Luciano , Arruti José Maurício Paiva Paiva Andion
Published: March 2018

Enquanto fechamos a organização deste volume da Revista da FAEEBA – Educação e Contemporaneidade e preparamos o seu texto de apresentação, entramos em mais um momento crítico do processo de reconhecimento dos direitos quilombolas. Estamos mais uma vez à espera de uma decisão do Supremo Tribunal Federal comrelação à constitucionalidade do decreto presidencial nº 4.887, de 2003, que regulamenta o artigo constitucional 68 (ADCT), de 1988, por meio do qual, pela primeira vez, o Estado brasileiro reconheceu a existência de comunidades remanescentes de quilombos e lhes atribuiu direitos territoriais.
TAJIKISTAN – RUSSIA RELATIONS IN HISTORICAL PERSPECTIVE
Authors: Sethi Jajneswar
Published: March 2018

attachment in various phases. The relationship between the two countries has always been a smooth one since the time of Tajikistan’s creation as a republic within Soviet Union. The relations have passed through various stages of development starting from the Tsarist colonial times to the present. Russia has been historically tied with Tajikistan and is one of the most important neighbours and guarantor of peace in the region Tajikistan depends fully on Russia to preserve the unity and integrity of its territory. Russia has not intervened coercively in the Tajik conflict, but has acted in support of a government with which it has treaty obligations. Russia sought to apply a supportive strategy of engagement designed to defend the border zone, support the Tajik Government and persuade the opposition to resolve the conflict peacefully on the relation between Tajikistan and Russia at present are geared to a very intensive search for the best forms, ways and means of cooperation.
A COMPARITIVE STUDY OF ANXIETY OF XI CLASS STUDENTS OF COMMERCE AND SCIENCE STREAM
Authors: Singh Geeta , Singh Dileep Kumar
Published: March 2018

The study investigates the anxiety of XI class students of commerce and science stream. The sample of the study consists 800 students from Mathura district of U.P. survey method was used for collection of data. The result of the study reveals that there is significant difference (0.01 level) between and anxiety level of students of commerce and science stream.