bluuebunny/crossref_metadata_2025 huggingface dataset:
Concerns about Quadrupole ICP-MS Lead Isotopic Data and Interpretations in the Environment and Health Fields
Authors: Gulson Brian , Kamenov George , Manton William , Rabinowitz Michael
Published: April 2018

There has been a massive increase in recent years of the use of lead (Pb) isotopes in attempts to better understand sources and pathways of Pb in the environment and in man or experimental animals. Unfortunately, there have been many cases where the quality of the isotopic data, especially that obtained by quadrupole inductively coupled plasma mass spectrometry (Q-ICP-MS), are questionable, resulting in questionable identification of potential sources, which, in turn, impacts study interpretation and conclusions. We present several cases where the isotopic data have compromised interpretation because of the use of only the major isotopes 208Pb/206Pb and 207Pb/206Pb, or their graphing in other combinations. We also present some examples comparing high precision data from thermal ionization (TIMS) or multi-collector plasma mass spectrometry (MC-ICP-MS) to illustrate the deficiency in the Q-ICP-MS data. In addition, we present cases where Pb isotopic ratios measured on Q-ICP-MS are virtually impossible for terrestrial samples. We also evaluate the Pb isotopic data for rat studies, which had concluded that Pb isotopic fractionation occurs between different organs and suggest that this notion of biological fractionation of Pb as an explanation for isotopic differences is not valid. Overall, the brief review of these case studies shows that Q-ICP-MS as commonly practiced is not a suitable technique for precise and accurate Pb isotopic analysis in the environment and health fields.
Deoxyribonucleic Acid Damage and Repair: Capitalizing on Our Understanding of the Mechanisms of Maintaining Genomic Integrity for Therapeutic Purposes
Authors: Helena Jolene , Joubert Anna , Grobbelaar Simone , Nolte Elsie , Nel Marcel , Pepper Michael , Coetzee Magdalena , Mercier Anne
Published: April 2018

Deoxyribonucleic acid (DNA) is the self-replicating hereditary material that provides a blueprint which, in collaboration with environmental influences, produces a structural and functional phenotype. As DNA coordinates and directs differentiation, growth, survival, and reproduction, it is responsible for life and the continuation of our species. Genome integrity requires the maintenance of DNA stability for the correct preservation of genetic information. This is facilitated by accurate DNA replication and precise DNA repair. DNA damage may arise from a wide range of both endogenous and exogenous sources but may be repaired through highly specific mechanisms. The most common mechanisms include mismatch, base excision, nucleotide excision, and double-strand DNA (dsDNA) break repair. Concurrent with regulation of the cell cycle, these mechanisms are precisely executed to ensure full restoration of damaged DNA. Failure or inaccuracy in DNA repair contributes to genome instability and loss of genetic information which may lead to mutations resulting in disease or loss of life. A detailed understanding of the mechanisms of DNA damage and its repair provides insight into disease pathogeneses and may facilitate diagnosis and the development of targeted therapies.
Delivery of Proapoptotic Agents in Glioma Cell Lines by TSPO Ligand–Dextran Nanogels
Authors: Lopalco Antonio , Cutrignelli Annalisa , Denora Nunzio , Perrone Mara , Iacobazzi Rosa , Fanizza Elisabetta , Lopedota Angela , Depalo Nicoletta , De Candia Modesto , Franco Massimo , Laquintana Valentino
Published: April 2018

Translocator protein 18-kDa (TSPO) is a versatile mitochondrial target for molecular imaging and therapy. Moreover, selective TSPO ligands have been widely investigated for diagnostic purposes and explored to target drug delivery systems directed to cancer cells overexpressing TSPO. Indeed, poly(d,l-lactic-co-glycolic acid (PLGA) polymers and nanocarriers decorated with TSPO ligands are capable of transporting TSPO ligands inside cancer cells, inducing survival inhibition in cancer cells and producing mitochondrial morphology modification. The aim of this work was to prepare nanogels (NGs) made with TSPO ligand dextran conjugates (TSPO-Dex) that are useful as potential delivery systems of two TSPO ligands as apoptotic agents. Synthesis and complete characterization of TSPO–dextran conjugates, an average molecular weights analysis, TSPO ligand release profiles, thermal behaviour and swelling studies were achieved. NG preparation, characterization and in vitro biological studies were also performed. The release of TSPO ligands released from dextran conjugates at 37 °C occurred in human serum at a faster rate than that detected in phosphate buffer. Cytotoxicity studies demonstrated that NGs produced from TSPO ligand–dextran conjugates induce survival inhibition in rat C6 glioma cell lines. Cellular uptake was also proven by fluorescence microscopy.
Conflicting Roles of Connexin43 in Tumor Invasion and Growth in the Central Nervous System
Authors: Uzu Miaki , Sin Wun , Shimizu Ayaka , Sato Hiromi
Published: April 2018

The tumor microenvironment is known to have increased levels of cytokines and metabolites, such as glutamate, due to their release from the surrounding cells. A normal cell around the tumor that responds to the inflammatory environment is likely to be subsequently altered. We discuss how these abnormalities will support tumor survival via the actions of gap junctions (GJs) and hemichannels (HCs) which are composed of hexamer of connexin43 (Cx43) protein. In particular, we discuss how GJ intercellular communication (GJIC) in glioma cells, the primary brain tumor, is a regulatory factor and its attenuation leads to tumor invasion. In contrast, the astrocytes, which are normal cells around the glioma, are “hijacked” by tumor cells, either by receiving the transmission of malignant substances from the cancer cells via GJIC, or perhaps via astrocytic HC activity through the paracrine signaling which enable the delivery of these substances to the distal astrocytes. This astrocytic signaling would promote tumor expansion in the brain. In addition, brain metastasis from peripheral tissues has also been known to be facilitated by GJs formed between cerebral vascular endothelial cells and cancer cells. Astrocytes and microglia are generally thought to eliminate cancer cells at the blood–brain barrier. In contrast, some reports suggest they facilitate tumor progression as tumor cells take advantage of the normal functions of astrocytes that support the survival of the neurons by exchanging nutrients and metabolites. In summary, GJIC is essential for the normal physiological function of growth and allowing the diffusion of physiological substances. Therefore, whether GJIC is cancer promoting or suppressing may be dependent on what permeates through GJs, when it is active, and to which cells. The nature of GJs, which has been ambiguous in brain tumor progression, needs to be revisited and understood together with new findings on Cx proteins and HC activities.
Opposing Roles of Calcium and Intracellular ATP on Gating of the Purinergic P2X2 Receptor Channel
Authors: Rokic Milos , Castro Patricio , Leiva-Salcedo Elias , Tomic Melanija , Stojilkovic Stanko , Coddou Claudio
Published: April 2018

P2X2 receptors (P2X2R) exhibit a slow desensitization during the initial ATP application and a progressive, calcium-dependent increase in rates of desensitization during repetitive stimulation. This pattern is observed in whole-cell recordings from cells expressing recombinant and native P2X2R. However, desensitization is not observed in perforated-patched cells and in two-electrode voltage clamped oocytes. Addition of ATP, but not ATPγS or GTP, in the pipette solution also abolishes progressive desensitization, whereas intracellular injection of apyrase facilitates receptor desensitization. Experiments with injection of alkaline phosphatase or addition of staurosporine and ATP in the intracellular solution suggest a role for a phosphorylation-dephosphorylation in receptor desensitization. Mutation of residues that are potential phosphorylation sites identified a critical role of the S363 residue in the intracellular ATP action. These findings indicate that intracellular calcium and ATP have opposing effects on P2X2R gating: calcium allosterically facilitates receptor desensitization and ATP covalently prevents the action of calcium. Single cell measurements further revealed that intracellular calcium stays elevated after washout in P2X2R-expressing cells and the blockade of mitochondrial sodium/calcium exchanger lowers calcium concentrations during washout periods to basal levels, suggesting a role of mitochondria in this process. Therefore, the metabolic state of the cell can influence P2X2R gating.
CA 19-9 Pancreatic Tumor Marker Fluorescence Immunosensing Detection via Immobilized Carbon Quantum Dots Conjugated Gold Nanocomposite
Authors: Alarfaj Nawal , El-Tohamy Maha , Oraby Hesham
Published: April 2018

The clinical detection of carbohydrate antigen 19-9 (CA 19-9), a tumor marker in biological samples, improves and facilitates the rapid screening and diagnosis of pancreatic cancer. A simple, low cost, fast, and green synthesis method to prepare a viable carbon quantum dots/gold (CQDs/Au) nanocomposite fluorescence immunosensing solution for the detection of CA 19-9 was reported. The present method is conducted by preparing glucose-derived CQDs using a microwave-assisted method. CQDs were employed as reducing and stabilizing agents for the preparation of a CQDs/Au nanocomposite. The immobilized anti-CA 19-9-labeled horseradish peroxidase enzyme (Ab–HRP) was anchored to the surface of a CQDs/Au nanocomposite by a peptide interaction between the carboxylic and amine active groups. The CA 19-9 antigen was trapped by another monoclonal antibody that was coated on the surface of microtiter wells. The formed sandwich capping antibody–antigen–antibody enzyme complex had tunable fluorescence properties that were detected under excitation and emission wavelengths of 420 and 530 nm. The increase in fluorescence intensities of the immunoassay sensing solution was proportional to the CA 19-9 antigen concentration in the linear range of 0.01–350 U mL−1 and had a lower detection limit of 0.007 U mL−1. The proposed CQDs/Au nanocomposite immunoassay method provides a promising tool for detecting CA 19-9 in human serum.
Non-Coding Transcript Heterogeneity in Mesothelioma: Insights from Asbestos-Exposed Mice
Authors: Felley-Bosco Emanuela , Rehrauer Hubert
Published: April 2018

Mesothelioma is an aggressive, rapidly fatal cancer and a better understanding of its molecular heterogeneity may help with making more efficient therapeutic strategies. Non-coding RNAs represent a larger part of the transcriptome but their contribution to diseases is not fully understood yet. We used recently obtained RNA-seq data from asbestos-exposed mice and performed data mining of publicly available datasets in order to evaluate how non-coding RNA contribute to mesothelioma heterogeneity. Nine non-coding RNAs are specifically elevated in mesothelioma tumors and contribute to human mesothelioma heterogeneity. Because some of them have known oncogenic properties, this study supports the concept of non-coding RNAs as cancer progenitor genes.
A Novel Synthetic Material, BMM, Accelerates Wound Repair by Stimulating Re-Epithelialization and Fibroblast Activation
Authors: Seo Ga , Hyun Changlim , Koh Dongsoo , Park Sanggyu , Lim Yoongho , Kim Young , Cho Moonjae
Published: April 2018

Cutaneous wound repair is an intricate process whereby the skin reprograms itself after injury. In the mid-phase of wound repair, the proliferation, migration, and differentiation of cells are the major mechanisms to lead remodeling. We investigated the effect of BMM ((1E,2E)-1,2-bis((6-bromo-2H-chromen-3-yl)methylene)hydrazine), a novel synthetic material, on the migration and viability of keratinocytes or fibroblasts using the in vitro scratch woundhealing, electric cell-substrate imedance sensing (ECIS), invasion, and MTT assays. Cell migration-related factors were analyzed using western blot, and we found that treatment with BMM stimulated the EMT pathway and focal adhesion kinase (FAK)/Src signaling. Differentiation of HaCaT keratinocyte and fibroblast cells was also stimulated by BMM and specifically, NOX2/4 contributed to the activation of fibroblasts for wound healing. Furthermore, BMM treated HaCaT keratinocyte and fibroblast-co-cultured cells increased migration and differentiation. TGF-β and Cyr61 were also secreted to a greater extent than in single cultured cells. In vivo experiments showed that treatment with BMM promotes wound closure by promoting re-epithelialization. In this study, we demonstrated that a novel synthetic material, BMM, is capable of promoting wound healing via the stimulation of re-epithelialization in the epidermis and the activation of fibroblasts in the dermis, in particular, via the acceleration of the interaction between the epidermis and dermis.
Beneficial Phytochemicals with Anti-Tumor Potential Revealed through Metabolic Profiling of New Red Pigmented Lettuces (Lactuca sativa L.)
Authors: Qin Xiao-Xiao , Zhang Ming-Yue , Han Ying-Yan , Hao Jing-Hong , Liu Chao-Jie , Fan Shuang-Xi
Published: April 2018

The present study aimed to compare polyphenols among red lettuce cultivars and identify suitable cultivars for the development and utilization of healthy vegetables. Polyphenols, mineral elements, and antioxidant activity were analyzed in the leaves of six red pigmented lettuce (Lactuca sativa L.) cultivars; thereafter, we assessed the anti-tumor effects of cultivar B-2, which displayed the highest antioxidant activity. Quadrupole–Orbitrap mass spectrometry analysis revealed four classes of polyphenols in these cultivars. The composition and contents of these metabolites varied significantly among cultivars and primarily depended on leaf color. The B-2 cultivar had the highest antioxidant potential than others because it contained the highest levels of polyphenols, especially anthocyanin, flavone, and phenolic acid; furthermore, this cultivar displayed anti-tumor effects against the human lung adenocarcinoma cell line A549, human hepatoma cell line Bel7402, human cancer colorectal adenoma cell line HCT-8, and HT-29 human colon cancer cell line. Hence, the new red-leaf lettuce cultivar B-2 has a distinct metabolite profile, with high potential for development and utilization of natural phytochemical and mineral resources in lettuces and can be used as a nutrient-dense food product.
Recent Advances in Soft E-Textiles
Authors: Mondal Kunal
Published: April 2018

E-textiles (electronic textiles) are fabrics that possesses electronic counterparts and electrical interconnects knitted into them, offering flexibility, stretchability, and a characteristic length scale that cannot be accomplished using other electronic manufacturing methods currently available. However, knitting is only one of the technologies in e-Textile integration. Other technologies, such as sewing, embroidery, and even single fiber-based manufacture technology, are widely employed in next-generation e-textiles. Components and interconnections are barely visible since they are connected intrinsically to soft fabrics that have attracted the attention of those in the fashion and textile industries. These textiles can effortlessly acclimatize themselves to the fast-changing wearable electronic markets with digital, computational, energy storage, and sensing requirements of any specific application. This mini-review focuses on recent advances in the field of e-textiles and focuses particularly on the materials and their functionalities.
Latest Innovations in the Treatment of Venous Disease
Authors: Attaran Robert R.
Published: April 2018

Venous disease is more common than peripheral arterial disease. Pathophysiologically, venous disease can be associated with obstruction, reflux, or both. A common feature in chronic venous disease is ambulatory venous hypertension. Inflammatory and pro-thrombotic mechanisms can be activated. The current therapies, including compression, ablation, and recanalization are discussed.
Novel Calcium Zirconate Silicate Cement Biomineralize and Seal Root Canals
Authors: Oh Soram , Cho Sung-In , Perinpanayagam Hiran , You Jinsu , Hong Seong-Hyeon , Yoo Yeon-Jee , Chang Seok , Shon Won-Jun , Yoo Jun-Sang , Baek Seung-Ho , Kum Kee-Yeon
Published: April 2018

This study evaluated the sealing ability of gutta-percha (GP) with a calcium silicate-based sealer and a novel calcium zirconate containing calcium silicate cement (ZC). The root canals of the extracted premolars were prepared, which were then randomly allocated to three experimental groups (12 root canals per group) for obturation by continuous wave of condensation with the GP and AH 26 sealer (CW); obturation using a single GP with a calcium silicate-based EndoSequence BC sealer (SC); or obturation with ZC. The roots were inserted into sterile Eppendorf tubes, which were inoculated coronally with Porphyromonas gingivalis. The amount of endotoxin leakage into the apical reservoirs were measured using the Limulus Amebocyte Lysate (LAL) assay over 21 days, with comparisons made using one-way ANOVA and Scheffe’s tests (α = 0.05). After 21 days, 75% of the canals that had been obturated by SC, 50% of those obturated by CW and 42% of those obturated by ZC showed endotoxin leakage. The amount of leakage was higher in the SC canals than in the CW (p = 0.031) or ZC (p = 0.03) canals, although there was no significant difference in the amount of leakage for CW and ZC (p > 0.05). X-ray diffraction revealed the presence of tricalcium silicate (Ca3SiO5) and calcium zirconate (CaZrO3) in the synthesized ZC. Scanning electron microscopy revealed mineralized precipitates on the dentin of canals obturated by ZC. The novel calcium zirconate silicate cement appears to promote biomineralization and seal root canals at least as effectively as the conventional sealer.
The Influence of Different Metal Ions on the Absorption Properties of Nano-Nickel Zinc Ferrite
Authors: Ma Zhijun , Mang Changye , Weng Xingyuan , Zhang Qi , Si Liwei , Zhao Haitao
Published: April 2018

The hydrothermal method was used to dope different amounts of Co2+, Mn2+, and Cu2+ in nano-nickel zinc ferrite powder. X-ray diffraction (XRD), a scanning electron microscopy (TEM), and a vector network analyzer (VNA) were used to explore the influence of doping on particle size, morphology, and electromagnetic wave absorption performance. Pure nanometer cobalt nickel zinc ferrite phase was prepared using the hydrothermal method with an increasing Co2+ content. Results showed that the grain type structure changed from a spherical structure to an irregular quadrilateral structure with the average particle size increasing from 35 nm to 60 nm. The lattice constant increased from 0.8352 to 0.8404 nm with Co2+ doping. The increasing Co2+ can change the position of the absorption peak, increase the bandwidth of the absorber, and improve the performance of the materials in GHz low frequency. The doping ratio of Mn2+ can affect the size of the lattice constant, but nanocrystals are easy to reunite without improving the electromagnetic loss. However, the absorbance performance decreases. For the doping of Cu2+, there is an agglomeration phenomenon. When the doping quantity is 0.15, the absorbing wave performance becomes better.
AC Iron Loss Prediction and Magnetic Properties of Fe-6.5 wt. % Si Ribbons Prepared by Melt-Spinning
Authors: Wang Shuai , Liang Yongfeng , Chen Biao , Ye Feng , Lin Junpin
Published: April 2018

Ultra-thin Fe-6.5 wt. % Si ribbons of 35 μm in thickness were prepared by melt-spinning. The magnetic properties were investigated before and after annealing at 1000 °C. The DC properties and low-frequency (400 Hz~10 kHz) iron losses significantly improved after heat treatment. A simplified formula— P t = k t B m N —based on the Steinmetz law, which can be used to predict the AC iron loss, is presented. The symbols “kt” and “N” are defined as functions of microstructure and frequency. According to the tested results of iron loss, the values of “kt” and “N” can be fitted and therefore the simplified formula can be determined. The extent of AC iron losses can be predicted according to the formula. The results obtained from the formula predict AC iron loss to a good degree. The method developed in this work could be extended to other magnetic materials for predicting AC iron loss with greater ease.
Light-Weight Aluminum-Based Alloys—From Fundamental Science to Engineering Applications
Authors: Wagner Martin
Published: April 2018

Academia and industry alike are faced with an ever-growing demand for energy-efficiency and reduced mass [...]
Quantitative Mineralogical Comparison between HPGR and Ball Mill Products of a Sn-Ta Ore
Authors: Hamid Sarbast , Alfonso Pura , Anticoi Hernan , Guasch Eduard , Oliva Josep , Dosbaba Marek , Garcia-Valles Maite , Chugunova Marina
Published: April 2018

The mineralogy and liberation characteristics of the comminuted Penouta leucogranite host of the Sn-Ta ore were determined. Grinding developed by a combination of high-pressure grinding rolls (HPGR) followed by a ball mill (BM) was compared with a single ball mill process. The mineral characteristics of the grinding products were analyzed using a Tescan Integrated Mineralogical Analyzer (TIMA-X) and X-ray powder diffraction (XRD). The ore contains 103 ppm of Ta and is mainly composed of quartz, albite, microcline, muscovite, and kaolinite. Nb, Ta-rich minerals are columbite-(Mn) and tantalite-(Mn), as well as minor microlite and wodginite. The liberation in the product is high in the size fraction of less than 250 µm (51–52 wt % for columbite-group minerals (CGM) and 74–80 wt % for cassiterite) and reduced in larger particles (8.8–17 wt % for CGM and 28–37 wt % for cassiterite). The recovery in the −250 µm fraction was high, while in the larger fraction it is limited, remaining up to 80 ppm in some tailings. The combined use of HPGR and a BM reduces the particle size distribution of the product and, thus, increases the liberation of the ores. Smaller fractions can be treated directly using gravity methods; however, particles of a size greater than +250 µm should be ground more.
Assessment of Industrial Modules to Design a GFMA Process for Cyanide Recovery Based on a Phenomenological Model
Authors: Estay Humberto , Troncoso Elizabeth , Ruby-Figueroa René , Romero Julio
Published: April 2018

Cyanide recovery in the gold-mining industry is a crucial step in terms of the cost of operation. Currently, a process such as AVR (acidification, volatilization and recycling), based on packed towers for stripping and absorption stages, addresses this issue with high levels of investment and operational costs. Gas-filled membrane absorption (GFMA) emerges then as an attractive alternative because the stripping and absorption stages can be performed in a single stage, reducing associated investment and operational costs. Despite the advantages of this technology, applications at industrial scale are still emerging. A possible reason is the lack of clear scaling-up methodologies where experimental data can be taken to select the optimum industrial hollow-fiber membrane contactor module (HFMC). The present study proposes a methodology to select adequately between available industrial Liqui-CelTM modules to design a process under optimal operational conditions. The methodology is based on a phenomenological model developed for recovering cyanide by using the GFMA process. Simulation of the Liqui-CelTM industrial membrane modules employed to recover cyanide in the GFMA process, both in a batch arrangement with a feed-flow rate, and in the range 10–125 m3/h, showed that in terms of cyanide recovery there are no differences between the modules tested when they work at the same feed-flow rate. The design criteria to scale-up was determined: to ensure performance at different scales, the length of the transfer unit (HTU) should be kept at different capacities of HFMC modules that comprise the equipment characteristics (mass-transfer area, stream velocities, and mass-transfer coefficient values). Additionally, the number of commercial modules Liqui-CelTM required to treat 57 m3/h and 250 m3/h ensuring a cyanide recovery of 95% was also determined. Finally, the most profitable option (lower pressure drop and module cost) resulted in the use of the 14 × 40 Liqui-CelTM module.
Advances in Multi-Sensor Information Fusion: Theory and Applications 2017
Authors: Jin Xue-Bo , Sun Shuli , Wei Hong , Yang Feng-Bao
Published: April 2018

The information fusion technique can integrate a large amount of data and knowledge representing the same real-world object and obtain a consistent, accurate, and useful representation of that object. The data may be independent or redundant, and can be obtained by different sensors at the same time or at different times. A suitable combination of investigative methods can substantially increase the profit of information in comparison with that from a single sensor. Multi-sensor information fusion has been a key issue in sensor research since the 1970s, and it has been applied in many fields. For example, manufacturing and process control industries can generate a lot of data, which have real, actionable business value. The fusion of these data can greatly improve productivity through digitization. The goal of this special issue is to report innovative ideas and solutions for multi-sensor information fusion in the emerging applications era, focusing on development, adoption, and applications.
High Dynamic Range Imaging at the Quantum Limit with Single Photon Avalanche Diode-Based Image Sensors
Authors: Dutton Neale , Al Abbas Tarek , Gyongy Istvan , Mattioli Della Rocca Francescopaolo , Henderson Robert
Published: April 2018

This paper examines methods to best exploit the High Dynamic Range (HDR) of the single photon avalanche diode (SPAD) in a high fill-factor HDR photon counting pixel that is scalable to megapixel arrays. The proposed method combines multi-exposure HDR with temporal oversampling in-pixel. We present a silicon demonstration IC with 96 × 40 array of 8.25 µm pitch 66% fill-factor SPAD-based pixels achieving >100 dB dynamic range with 3 back-to-back exposures (short, mid, long). Each pixel sums 15 bit-planes or binary field images internally to constitute one frame providing 3.75× data compression, hence the 1k frames per second (FPS) output off-chip represents 45,000 individual field images per second on chip. Two future projections of this work are described: scaling SPAD-based image sensors to HDR 1 MPixel formats and shrinking the pixel pitch to 1–3 µm.
Infrared and Visible Image Fusion Based on Different Constraints in the Non-Subsampled Shearlet Transform Domain
Authors: Huang Yan , Bi Duyan , Wu Dongpeng
Published: April 2018

There are many artificial parameters when fuse infrared and visible images, to overcome the lack of detail in the fusion image because of the artifacts, a novel fusion algorithm for infrared and visible images that is based on different constraints in non-subsampled shearlet transform (NSST) domain is proposed. There are high bands and low bands of images that are decomposed by the NSST. After analyzing the characters of the bands, fusing the high level bands by the gradient constraint, the fused image can obtain more details; fusing the low bands by the constraint of saliency in the images, the targets are more salient. Before the inverse NSST, the Nash equilibrium is used to update the coefficient. The fused images and the quantitative results demonstrate that our method is more effective in reserving details and highlighting the targets when compared with other state-of-the-art methods.
Drone Mission Definition and Implementation for Automated Infrastructure Inspection Using Airborne Sensors
Authors: Besada Juan A. , Bergesio Luca , Campaña Iván , Vaquero-Melchor Diego , López-Araquistain Jaime , Bernardos Ana M. , Casar José R.
Published: April 2018

This paper describes a Mission Definition System and the automated flight process it enables to implement measurement plans for discrete infrastructure inspections using aerial platforms, and specifically multi-rotor drones. The mission definition aims at improving planning efficiency with respect to state-of-the-art waypoint-based techniques, using high-level mission definition primitives and linking them with realistic flight models to simulate the inspection in advance. It also provides flight scripts and measurement plans which can be executed by commercial drones. Its user interfaces facilitate mission definition, pre-flight 3D synthetic mission visualisation and flight evaluation. Results are delivered for a set of representative infrastructure inspection flights, showing the accuracy of the flight prediction tools in actual operations using automated flight control.
Influence of Tillage Practices, Organic Manures and Extrinsic Factors on β-Glucosidase Activity: The Final Step of Cellulose Hydrolysis
Authors: Mariscal-Sancho Ignacio , Ball Bruce , McKenzie Blair
Published: April 2018

β-glucosidase is a key enzyme in the C-cycle, and its activity is strongly influenced by soil management practices and by extrinsic factors such as weather conditions. However, the variability of β-glucosidase activity (BGa) over time and how this variability is affected by tillage and organic fertilization remain poorly elucidated. We investigated how contrasting tillage practices (zero, minimum, conventional or deep) and organic amendment application (dairy cattle slurry or green compost) govern BGa. Strong correlations (r = −0.98; p < 0.001) were found between BGa and preceding cumulative rainfall for soil without crops. Under cropped soil conditions, BGa was 53% greater under zero and minimum tillage than under ploughed treatments (p < 0.05) six years after their applications. These differences could be explained by associated effects of tillage on organic matter content, electrical conductivity and water stable aggregates. The separated organic residue experiment showed that BGa was 36% greater in soil amended with slurry than in soil amended with compost (p < 0.05) five years after their applications. Finally, the response ratio of BGa was calculated in order to study the effect size of each treatment at each sampling period. This simple strategy mitigated the variation on BGa measurements between two sampling periods, and may be applied in future studies to improve the interpretation of other potential soil quality indicators that are sensitive to seasonal changes.
The Influence of Fatigued Core Muscles on Head Acceleration during Headers in Soccer
Authors: Becker Stephan , Fröhlich Michael , Kelm Jens , Ludwig Oliver
Published: April 2018

The core muscles play a central role in stabilizing the head during headers in soccer. The objective of this study was to examine the influence of a fatigued core musculature on the acceleration of the head during jump headers and run headers. Acceleration of the head was measured in a pre-post-design in 68 soccer players (age: 21.5 ± 3.8 years, height: 180.0 ± 13.9 cm, weight: 76.9 ± 8.1 kg). Data were recorded by means of a telemetric 3D acceleration sensor and with a pendulum header. The treatment encompassed two exercises each for the ventral, lateral, and dorsal muscle chains. The acceleration of the head between pre- and post-test was reduced by 0.3 G (p = 0.011) in jump headers and by 0.2 G (p = 0.067) in run headers. An additional analysis of all pretests showed an increased acceleration in run headers when compared to stand headers (p < 0.001) and jump headers (p < 0.001). No differences were found in the sub-group comparisons: semi-professional vs. recreational players, offensive vs. defensive players. Based on the results, we conclude that the acceleration of the head after fatiguing the core muscles does not increase, which stands in contrast to postulated expectations. More tests with accelerated soccer balls are required for a conclusive statement.
Impact of an Ultraviolet Reactor on the Improvement of Air Quality Leaving a Direct Evaporative Cooler
Authors: Kim Wonjun , Dong Hye-Won , Park Junseok , Sung Minki , Jeong Jae-Weon
Published: April 2018

The purpose of this study is to improve microbial air quality by improving water quality, particularly concerning microbiological aspects, by applying an ultraviolet water purifier system to a direct evaporative cooling (DEC) system. A direct evaporative cooler is an air cooling technique that uses the evaporation of water. Most DECs recirculate water to reduce water use. Evaporative cooling pads and water are biologically contaminated by recirculating water. This contamination can develop into air contamination and cause respiratory illnesses in occupants. It is necessary to use sterilized water in a DEC to prevent respiratory diseases and maintain air quality. In this study, we examine whether improvements in water quality in a DEC affect air quality by dividing experiments into a control group (Control) and a treated group (UV-treated). In the control group, the degree of contamination was measured when a DEC operated for four weeks without ultraviolet water treatment. In UV-treated, the degree of contamination was measured when UV water treatment was applied to a DEC for four weeks. In both Control and UV-treated, microbes were sampled from the water, the evaporative cooling pad surface, and the DEC inlet and outlet air samples in order to compare the levels of contamination. The surface was measured once at four points, and the air was measured four times at two points. A comparison of the two experiments indicated that the degree of microbial contamination of water and air was significantly reduced in the UV-treated group when compared to that in the control group. When the pollution degree of the evaporative cooling pad was compared to the degree of air pollution, it was difficult to obtain a correlation between the two factors, although the results confirmed that the contamination of the evaporative cooling pad caused water pollution. Therefore, it is necessary to operate a water treatment system to maintain the clean air in DECs.
Carbon Footprints of Urban Residential Buildings: A Household Survey-Based Approach
Authors: Yan Xiaomei , Cui Shenghui , Xu Lilai , Lin Jianyi , Ali Ghaffar
Published: April 2018

With China’s rapid urbanization process, massive and extensive construction materials are aggregated as stock in urban areas. Understanding the carbon footprints of residential buildings is crucial for achieving the goal of low-carbon cities. In this study, to reveal the emission characteristics of residential buildings regarding carbon footprint, stratified random sampling was developed, and a face-to-face questionnaire was conducted, to obtain critical information on residential buildings and the socio-economic status of 1092 families from 46 communities in Xiamen City, China. The community buildings’ structures were identified, and carbon emissions from the residential buildings were quantified based on analysis of the entire building life cycle. The building life cycle can be divided into six stages: extraction and production; transportation; construction; operation; demolition; and recycling. The household carbon footprints ranged from 0.37 tCO2/year to 22.45 tCO2/year; the per capita carbon footprints ranged from 0.19 tCO2/year to 11.23 tCO2/year. Overall, for the 46 surveyed communities, the average household and per capita carbon footprints were 4.11 tCO2/year and 1.4 tCO2/year, respectively. The total carbon footprints of urban residential buildings were 4.86 MtCO2/year. Analysis of the extraction and production stage revealed that steel recycling could avoid almost 0.05 MtCO2/year. No significant correlations were found between energy use awareness and energy use. The findings can be used by Chinese energy policymakers to understand the views of various energy users, and to re-attune the efforts against these opinions and interests. However, we consider this study a start and not an end to the importance of gauging opinions on energy security from the population of energy users. Nonetheless, awareness campaigns through print and electronic media could be another tool for life cycle emissions reduction in building sector.
What You Sow Is What You Reap? (Dis-)Incentives for Adaptation Intentions in Farming
Authors: Buelow Franca , Cradock-Henry Nicholas
Published: April 2018

Adaptation by farmers and other land managers responsible for climate-sensitive activities is central to ensuring resilience in the face of ongoing climate variability and change. However, there remains an adaptation deficit among agricultural producers: action to reduce vulnerability to the impacts of climate change is insufficient. To motivate adaptation, diverse incentives are in place most notably through the European Union’s Common Agricultural Policy which offers financial incentives to farmers. However, the effect of incentives on behaviour appears to be low. To better understand adaptation intentions, we report on the results of a survey experiment assessing framing effects on German farmers. Four framings of adaptation motifs—financial, norms, risk awareness, and technological innovation—are tested against a socio-cognitive model based on Protection Motivation Theory (PMT). According to PMT, adaptation intentions are a function of an individual’s risk and coping appraisal. Results show that, contrary to assumptions of profit maximizing individuals, economic incentives trigger fewer overall change intentions. Economic rewards do act on risk perception, but are less likely to trigger coping perception, while other treatments do. As coping perception is one of two socio-cognitive reactions to climate change, financial incentive structures fail to act on about half the factors leading to adaptation intentions. These effects dependent on subgroups, farm structures, and are mediated by climate experience. To support transitions towards robust adaptation, adaptation incentives must move beyond financial framings alone, and leverage on farmers’ recent experiences with adverse climate impacts, understandings of climate change, and the influence of social norms.
Quantifying Surface Coal-Mining Patterns to Promote Regional Sustainability in Ordos, Inner Mongolia
Authors: Zeng Xiaoji , Liu Zhifeng , He Chunyang , Ma Qun , Wu Jianguo
Published: April 2018

Ordos became the new “coal capital” of China within a few decades since the country’s economic reform in 1978, as large-scale surface coal mining dramatically propelled its per capita GDP from being one of the lowest to one of the highest in China, exceeding Hong Kong in 2009. Surface coal-mining areas (SCMAs) have continued to expand in this region during recent decades, resulting in serious environmental and socioeconomic consequences. To understand these impacts and promote regional sustainability, quantifying the spatiotemporal patterns of SCMAs is urgently needed. Thus, the main objectives of this study were to quantify the spatiotemporal patterns of SCMAs in the Ordos region from 1990 to 2015, and to examine some of the major environmental and socioeconomic impacts in the study region. We extracted the SCMAs using remote-sensing data, and then quantified their spatiotemporal patterns using landscape metrics. The loss of natural habitat and several socioeconomic indicators were examined in relation to surface coal mining. Our results show that the area of SCMAs increased from 7.12 km2 to 355.95 km2, an increase of nearly 49 times from 1990 to 2015 in the Ordos region. The number of SCMAs in this region increased from 82 to 651, a nearly seven-fold increase. In particular, Zhungeer banner (an administrative division), Yijinhuoluo banner, Dongsheng District and Dalate banner in the north-eastern part of the Ordos region had higher growth rates of SCMAs. The income gap between urban and rural residents increased along with the growth in SCMAs, undermining social equity in the Ordos region. Moreover, the rapid increase in SCMAs resulted in natural habitat loss (including grasslands, forests, and deserts) across this region. Thus, we suggest that regional sustainability in Ordos needs to emphasize effective measures to curb large-scale surface coal mining in order to reduce the urban–rural income gap, and to restore degraded natural ecosystems.
Seismic and Energy Retrofit of the Historic Urban Fabric of Enna (Italy)
Authors: Basiricò Tiziana , Enea Daniele
Published: April 2018

This paper exemplifies several methods for retrofitting existing housing through four case studies, representative of the historical centre of Enna, a small town in Sicily, according to the requirements of static safety, typological adaptation and indoor comfort. These buildings were mostly built in the nineteenth century, up to three floors based on load-bearing masonry, iron joists and hollow tile floors and wooden roofs. A typological and construction analysis of these buildings was carried out to identify the stratigraphy of the different technical elements. Static and energy audits had been previously undertaken to understand the gap between the current state of the buildings and Italian standards and to develop appropriate interventions taking into account the site characteristics and the energy and seismic risk class pre- and post-retrofit intervention. The analyses and the retrofit interventions were performed in compliance with Italian standards and laws and strove to reach the minimum level. The study supports the planning of structural and energy retrofit interventions designed for historic load-bearing masonry buildings. Finally, the study simulates a strategy of action to provide subsidies and tax relief related to effective seismic and/or energy improvement that could be relevant for owners/builders as well as for local authorities.
Eco-Innovation in Circular Agri-Business
Authors: Shih Dong-Her , Lu Chia-Ming , Lee Chia-Hao , Cai Sin-Ye , Wu Kuo-Jui , Tseng Ming-Lang
Published: April 2018

This study constructs a theory of eco-innovation in circular agri-business. Although previous studies have discussed eco-innovation in circular agri-business, they did not address eco-innovation from the perspective of a closed-loop sustainable supply chain. Hence, this study applied the fuzzy TOPSIS method to conduct the analysis and determine the interrelationship between eco-innovation and the closed-loop concept. The results are consistent with the theory and a significant improvement in terms of the decisive attributes. The findings suggest that improving water management, relationships with suppliers, knowledge sharing, environmental management systems, and new product and service development are the most effective and efficient ways to build eco-innovation in circular agri-business. The managerial and theoretical implications are discussed.
We Don’t Want to Be Officially Certified! Reasons and Implications of the Participatory Guarantee Systems
Authors: Cuéllar-Padilla Mamen , Ganuza-Fernandez Ernesto
Published: April 2018

Official organic regulation in Europe is based on the third-party certification system to guarantee organic products. Many critics and dissatisfactions have motivated the emergence of other guarantee systems, based on an intense implication of producers and, in some cases, consumers and other local actors, involved in localised agri-food systems. They are called Participatory Guarantee Systems (PGS), and are not recognised as valid guarantee systems by the official organic regulation. In the present paper, we analyse the main differences between the PGS and the third party certification system, deepening on their differentiated social and political implications. We conclude that the procedures behind PGS generate numerous positive impacts in the territories related to local producers (and consumers) empowerment and localised agri-food systems drive, while their implications make them not considered as a substitute to third party certification system, unless certain conditions of social consolidated groups and agroecological and food sovereignty perspective of food system take place.
Bike Sharing and the Economy, the Environment, and Health-Related Externalities
Authors: Qiu Lu-Yi , He Ling-Yun
Published: April 2018

In recent years, bike-sharing has experienced rapid development; however, controversies about the externalities of bike-sharing programs have arisen as well. While bike-sharing programs have impacts on traffic, the environment, and public health, the social impacts, the management, and sustainable development of bike-sharing has also been of interest. The debate regards whether there are externalities, as well as whether and how such externalities can be determined. Based on the rapidly diffused bike-sharing in China, this paper quantitatively explores bike-sharing externalities. Specifically, this paper estimates the impacts of bike-sharing on the economy, energy use, the environment, and public health. The empirical results show that bike-sharing programs have significant positive externalities. The bike-sharing systems can provide urban residents with a convenient and time-saving travel mode. We find that the bike-sharing dramatically decreases traffic, reduces energy consumption, decreasing harmful gas emissions, improves public health generally, and promotes economic growth. This study contributes to a better comprehension of the externalities of bike-sharing and provides empirical evidence of the impacts of bike-sharing. Findings suggest that bike-sharing can play a critical role in the process of urban transportation development and provide information useful for urban transportation policies.
A Framework for Circular Multilevel Systems in the Frequency Domain
Authors: Sun Guomin , Leng Jinsong , Cattani Carlo
Published: April 2018

In this paper, we will construct a new multilevel system in the Fourier domain using the harmonic wavelet. The main advantages of harmonic wavelet are that its frequency spectrum is confined exactly to an octave band, and its simple definition just as Haar wavelet. The constructed multilevel system has the circular shape, which forms a partition of the frequency domain by shifting and scaling the basic wavelet functions. To possess the circular shape, a new type of sampling grid, the circular-polar grid (CPG), is defined and also the corresponding modified Fourier transform. The CPG consists of equal space along rays, where different rays are equally angled. The main difference between the classic polar grid and CPG is the even sampling on polar coordinates. Another obvious difference is that the modified Fourier transform has a circular shape in the frequency domain while the polar transform has a square shape. The proposed sampling grid and the new defined Fourier transform constitute a completely Fourier transform system, more importantly, the harmonic wavelet based multilevel system defined on the proposed sampling grid is more suitable for the distribution of general images in the Fourier domain.