bluuebunny/crossref_metadata_2025 huggingface dataset:
Associations Between Cognitive Complaints, Memory Performance, Mood, and Amyloid-β Accumulation in Healthy Amyloid Negative Late-Midlife Individuals
Authors: Narbutas Justinas , Van Egroo Maxime , Chylinski Daphne , Bahri Mohamed Ali , Koshmanova Ekaterina , Talwar Puneet , Besson Gabriel , Muto Vincenzo , Schmidt Christina , Luxen André , Balteau Evelyne , Phillips Christophe , Maquet Pierre , Salmon Eric , Bastin Christine , Vandewalle Gilles , Collette Fabienne
Published: July 2021

Background: Cognitive complaints are gaining more attention as they may represent an early marker of increased risk for AD in individuals without objective decline at standard neuropsychological examination. Objective: Our aim was to assess whether cognitive complaints in late middle-aged individuals not seeking medical help are related to objective cognitive outcomes known as early markers for AD risk, concomitant affective state, and amyloid-β (Aβ) burden. Methods: Eighty-seven community-based cognitively normal individuals aged 50–69 years underwent neuropsychological assessment for global cognition, using Preclinical Alzheimer’s Cognitive Composite 5 (PACC5) score, and a more specific episodic memory measure. Affective state was based on self-assessment questionnaires for depression and anxiety. Aβ PET burden was assessed via [18F]Flutemetamol (N = 84) and [18F]Florbetapir (N = 3) uptake. Cognitive complaints were evaluated using Cognitive Difficulties Scale. Results: Higher cognitive complaints were significantly associated with lower episodic memory performance and worse affective state. Moreover, higher level of cognitive complaints was related to higher (but still sub-clinical) global Aβ accumulation (at uncorrected significance level). Importantly, all three aspects remained significant when taken together in the same statistical model, indicating that they explained distinct parts of variance. Conclusion: In healthy Aβ negative late middle-aged individuals, a higher degree of cognitive complaints is associated with lower episodic memory efficiency, more anxiety and depression, as well as, potentially, with higher Aβ burden, suggesting that complaints might signal subtle decline. Future studies should untangle how cognitive complaints in healthy aging populations are related to longitudinal changes in objective cognition and AD biomarker correlates.
Multiple criteria decision making based on Hamy mean operators under the environment of spherical fuzzy sets
Authors: Sindhu Muhammad Sarwar , Rashid Tabasam , Kashif Agha
Published: July 2021

Aggregation operators are widely applied to accumulate the vague and uncertain information in these days. Hamy mean (HM) operators play a vital role to accumulate the information. HM operators give us a more general and stretchy approach to develop the connections between the arguments. Spherical fuzzy sets (SpFSs), the further extension of picture fuzzy sets (PcFSs) that handle the data in which square sum of membership degree (MD), non-membership degree (NMD) and neutral degree (ND) always lie between closed interval [0, 1]. In the present article, we modify the HM operators like spherical fuzzy HM (SpFHM) operator and weighted spherical fuzzy HM (WSpFHM) operator to accumulate the spherical fuzzy (SpF) information. Moreover, various properties and some particular cases of SpFHM and the WSpFHM operators are discussed in details. Also, to compare the results obtained from the HM operators a score function is developed. Based on WSpFHM operator and score function, a model for multiple criteria decision-making (MCDM) is established to resolve the MCDM problem. To check the significance and robustness of the result, a comparative analysis and sensitivity analysis is also performed.
Artificial intelligence based prediction models: sales forecasting application in automotive aftermarket
Authors: Türkbayrağí Mert Girayhan , Dogu Elif , Esra Albayrak Y.
Published: July 2021

Automotive aftermarket industry is possessed of a wide product portfolio range which is in the 4th rank by its worldwide trade volume. The demand characteristic of automotive aftermarket parts is volatile and uncertain. Nevertheless, the cause-and-effect relationship of automotive aftermarket industry has not been defined obviously heretofore. These conditions bring automotive aftermarket sales forecasting into a challenging process. This paper is composed to determine the relevant external factors for automotive aftermarket sales based on expert reviews and to propose a sales forecasting model for automotive aftermarket industry. Since computational intelligence techniques yield a framework to focus on predictive analytics and prescriptive analytics, an artificial neural network model constructed for Turkey automotive aftermarket industry. Artificial intelligence is a subset of computational intelligence that focused on problems which have complex and nonlinear relationships. The data which have complex and nonlinear relationships could be modelled successfully even though incomplete data in case of implementation of appropriate model. The proposed ANN model for sales forecast is compared with multiple linear regression and revealed a higher prediction performance.
A revised weighted fuzzy c-means and Nelder-Mead algorithm for probabilistic demand and customer positions
Authors: Bayturk Engin , Esnaf Sakir , Kucukdeniz Tarik
Published: July 2021

Facility location selection is a vital decision for companies that affects both cost and delivery time over the years. However, determination of the facility location is a NP-hard problem. A hybrid algorithm that combines revised weighted fuzzy c-means with Nelder Mead (RWFCM-NM) performs well when compared with well-known algorithms for the facility location problem (FLP) with deterministic customer demands and positions. The motivation of the study is both analyzing performance of the RWFCM-NM algorithm with probabilistic customer demands and positions and proposing a new approach for this problem. This paper develops two new algorithms for FLP when customer demands and positions are probabilistic. The proposed algorithms are a probabilistic fuzzy c-means algorithm and Nelder-Mead (Probabilistic FCM-NM), a probabilistic revised weighted fuzzy c-means algorithm and Nelder Mead (Probabilistic RWFCM-NM) for the un-capacitated planar multi-facility location problem when customer positions and customer demands are probabilistic with predetermined service level. Proposed algorithms performances were tested with 13 data sets and comparisons were made with four well known algorithms. According to the experimental results, probabilistic RWFCM-NM algorithm demonstrates superiority on compared algorithms in terms of total transportation costs.
Mechanism to determine quantitatively characterize the level of concentration of pollutants emissions road transport
Authors: Trysnyuk Vasyl M. , Shumeiko Viktor O. , Holowan Yuriy M.
Published: July 2021

The basic mechanisms of pollution of the surface atmosphere and upper soil layer emission car transport roadside strip. Road transport, together with heavy industry, is one of the main air pollutants. Exhaust gases, crankcase gases, smoke, soot lead to complex chemical reactions in the surface layer of the atmosphere. Presented a number of methods to assess the level of contamination, analyses their strengths and weaknesses. Considered methodology issuance previous forecast spread of contamination including disturbing factors and their impact on the concentration of contaminants, as well as mathematical tools to determine the quantitative characteristics of concentration levels pollutants substances. The developed methodology is one of the ways to issue a preliminary forecast of the spread of pollution, taking into account disturbing factors in the presence of a priori data. This methodology takes into account a set of factors influencing the level of pollution concentration and the empirically obtained functional dependences of the influence of each of the disturbing components on the level of pollution. The constructed model of interaction of the established factors in the form of the graph of interaction characterizes causal relations.
Field Data Report for the First Microwave Water and Energy Balance Experiment (MicroWEX-1), July 17 - December 16, 2003, Citra, Florida
Authors: Tien Kai-Jen Calvin , Judge Jasmeet , Miller Larry W. , Lanni Orlando L.
Published: July 2021

Many studies have been conducted in agricultural areas such as bare soil, grass, soybean, wheat, pasture, and corn to understand the relationship between soil moisture and microwave remote sensing. Most of these experiments conducted in agricultural regions have been short-term experiments that captured only a part of growing seasons. It is important to know how microwave brightness signature varies with soil moisture, evapotranspiration (ET), and biomass in a dynamic agricultural canopy with a significant biomass (4-6 kg/m2 ) throughout the growing season. This document is Circular 1470, one of a series of the Agricultural and Biological Engineering Department, Agricultural Research Station, Institute of Food and Agricultural Sciences, University of Florida. First published April 2005. 

Cicular 14/AE288: Field Data Report for the First Microwave Water and Energy Balance Experiment (MicroWEX-1), July 17–December 16, 2003, Citra, Florida (ufl.edu)
Study Questions for the Certified Pesticide Applicator Examination: Natural Areas Weed Management
Authors: Langeland Ken A.
Published: July 2021

The following questions are intended to help prepare you for taking the Natural Areas Weed Management Certified Pesticide Applicator Examination. It should be used along with IFAS publications SP 295 Natural Area Weed Management - A Training Manual for Restricted Use Pesticide Applicators and SP 257 Identification & Biology of Non-Native Plants in Florida’s Natural Areas, which can be obtained from the IFAS Extension Book store by calling 800-226-1764 (local 359-392-1764) or from http://ifasbooks.ufl.edu. For some questions you will need a copy of a Garlon 4 herbicide label, which can be obtained from http://www.cdms.net/manuf/manuf.asp. Answers to all questions can be found in these publications. You will greatly improve your ability to achieve a passing examination score by locating the answers to the study questions and writing them down. This document is SS-AGR-255, one of a series of the Agronomy Department, Florida Cooperative Extension Service, Instituteof Food and Agricultural Sciences, University of Florida. Published August 2005.
Common Freshwater Fish Parasites Pictorial Guide: Crustaceans
Authors: Pouder Deborah B. , Curtis Eric W. , Yanong Roy P.
Published: July 2021

This publication is one in a series of pictorial guides that is designed to assist in the identification of common freshwater fish parasites. The information provided in this guide is not intended to be a complete, detailed description of each parasite or parasite group and its characteristics but rather is intended to assist in the visual identification of some of the most common species or groups of parasites seen in freshwater fish. For further information on each parasite, refer to publications in the “Recommended Reading” and “Reference” sections. This document is Fact Sheet FA-115, one of a series from the Tropical Aquaculture Laboratory, Department of Fisheries and Aquatic Sciences, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. First published: July 2005. 

FA-115/FA115: Common Freshwater Fish Parasites Pictorial Guide: Crustaceans (ufl.edu)
Juice HACCP Program: An Overview
Authors: Goodrich Renee M. , Schneider Keith R. , Parish M. E.
Published: July 2021

Juice HACCP commonly refers to the use of HACCP systems to minimize food safety risks in the juice processing, packaging, and transportation industries. The acronym HACCP stands for Hazard Analysis Critical Control Point (pronounced 'hás•sip'). Significant hazards for a particular juice, puree, or concentrate are identified, based upon scientific information. The steps at which these hazards can be controlled within the process are identified, and the critical limits at each of the key process steps are set. Monitoring procedures are implemented to evaluate conformance with these critical limits. Should the process fall outside these limits, pre-planned corrective actions are taken to prevent the potentially defective product from entering the commerce stream. In addition, the HACCP system relies on extensive verification and documentation to assure that food safety has not been compromised. Thus, HACCP provides a structure for assessing risks or what could go wrong, and for putting the controls in place to minimize such risks. This document is FSHN0515, one of a series of the Food Science and Human Nutrition Department, UF/IFAS Extension. Published August 2005.

FSHN0515/FS124: The Juice HACCP Program: An Overview (ufl.edu)
Field Diagnosis of Citrus Root Weevil Damage
Authors: Futch Stephen H. , McCoy Clayton W. , Graham James H. , Duncan Larry W. , Nigg Herbert N.
Published: July 2021

Root weevils infest citrus groves throughout the citrus growing regions of Florida. Among the eight weevil species that have been identified in Florida citrus groves, five have some potential to cause economic problems for nurserymen and commercial growers. The most important weevil species are Diaprepes root weevil (Diaprepes abbreviatus), southern blue-green citrus root weevil (Pachnaeus litus), and the blue-green citrus root weevil (Pachnaeus opalus). The little leaf notcher (Artipus floridanus) and Fuller rose beetle (Asynonychus godmani) are of less concern, but may be locally important (Fig. 1). This paper will deal with Diaprepes and the blue-green root weevils because they are of major economic importance and frequently occur in citrus groves. This document is HS-1014, one of a series of the Horticultural Sciences Department, UF/IFAS Extension. Original publication date May 2005.

HS-1014/HS260: Field Diagnosis of Citrus Root Weevil Damage (ufl.edu)
Field Identification and Management of Greasy Spot Disease
Authors: Futch S. H. , Timmer L. W.
Published: July 2021

Greasy spot is a disease that's frequently found in tropical and semitropical regions where citrus cultivars are grown. The disease is caused by Mycosphaerella citri. Symptoms appear as yellow to dark brown to black lesions occurring first on the underside of mature citrus leaves (Fig. 1). As the lesions develop on the underside of the leaves, they become darker and a corresponding chlorotic spot will appear on the upper leaf surface. These yellow (chlorotic) spots occur when infected cells fail to develop chlorophyll. Lesions are more yellowish and diffuse on lemons and grapefruit and more raised and darker on tangerines. Affected leaves fall prematurely from the tree during the fall and winter resulting in reduced tree vigor and yield. Greasy spot also infects the fruit of grapefruit trees producing rind blotch.  This document is HS-1016, one of a series of the Horticultural Sciences Department, UF/IFAS Extension. Original publication date May 2005.

HS-1016/HS263: Field Identification and Management of Greasy Spot Disease (ufl.edu)
Tomato Bug, Tobacco Leaf Bug, Tomato Mirid, Green Tobacco Capsid Nesidiocoris tenuis Reuter (Insecta: Hemiptera: Miridae)
Authors: Adeleye Victoria Oluwaseun , Seal Dakshina R.
Published: July 2021

The Featured Creatures collection provides in-depth profiles of insects, nematodes, arachnids and other organisms relevant to Florida. These profiles are intended for the use of interested laypersons with some knowledge of biology as well as academic audiences.
Getting Started in Butterfly Gardening
Authors: Sprenkel Richard K.
Published: July 2021

This publication was developed for individuals who are just getting started in butterfly gardening or who want to pursue the hobby with a good chance of success. This document is ENY-722, one of a series of Entomology and Nematology Department, Florida Cooperative Extension Services, Institute of Food and Agricultural Sciences, University of Florida. Publication Date:  February 2005.
How Scientists Obtain Approval to Release Organisms for Classical Biological Control of Invasive Weeds
Authors: Scoles John C. , Cuda James P. , Overholt William A.
Published: July 2021

An invasive weed is a nonnative plant that exhibits rapid population growth following its arrival in a new environment where it did not evolve. The success of the weed in its new habitat is due in part to the absence of the natural enemies that normally limit its reproduction and spread in its native range. Classical biological control seeks to reunite an invasive weed with one or more of its co-evolved natural enemies to provide permanent control of the weed. This document is ENY-828, one of a series of the Department of Entomology and Nematology, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. Published: May 2005.

ENY-828/IN607: How Scientists Obtain Approval to Release Organisms for Classical Biological Control of Invasive Weeds (ufl.edu)
Wildlife and Hunting As Alternative Farm Enterprises
Authors: Giuliano William M. , Thomas Kristin C.
Published: July 2021

Wildlife enhances our quality of life and is an integral part of the landscape. In addition, wildlife can be managed to provide revenue as part of alternative farm enterprises. The key to maintaining healthy wildlife populations necessary in such alternative enterprises is providing quality habitat through proper management (Figure 1). This document is WEC 197 and one of a series of the Department of Wildlife Ecology and Conservation, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences (IFAS), University of Florida. First published: July 2005.
More Than a “Bad Apple”: Expanding Care Considerations for Strategic Communication in a Collective Crisis
Authors: Madden Stephanie , Alt Rebecca A.
Published: July 2021

The Larry Nassar case is one of many abuse stories within and beyond sports. Although conventional strategies of image repair such as identifying one “bad apple” are considered effective within an ethics of justice perspective, we argue that crisis responses must adopt an ethics of care when physical and emotional harm has occurred. Using a case study approach, we qualitatively analyzed organizational responses from Michigan State University (MSU), U.S.A. Gymnastics (USAG), and the U.S. Olympic Committee (USOC), as well as media coverage of Nassar’s sentencing hearing, through Fraustino and Kennedy’s (2018) Applied Model of Care Considerations (AMCC) framework. We theorize how the media landscape creates a space of resistance for survivors that facilitates ethics of care in a collective crisis.
ANALISIS KEBIJAKAN RENCANA TUNTUTAN (RENTUT) DI INTERNAL KEJAKSAAN INDONESIA
Authors: Vivi Arfiani Siregar Vivi Arfiani Siregar
Published: July 2021

Kewenangan penuntutan oleh Jaksa Agung kemudian didelegasikan oleh jajaran di bawahnya, yaitu Kepala Kejaksaan Tinggi dan Kepala Kejaksaan Negeri, sehingga mekanisme pengajuan rentut dari Penuntut Umum harus kepada Kepala Kejaksaan Negeri dan pada perkara-perkara tertentu, kepada Kepala Kejaksaan Tinggi atau Jaksa Agung. Adanya intervensi pimpinan terhadap penentuan Tuntutan Pidana tersebut, merupakan salah satu hal pokok yang mempengaruhi Independensi Jaksa selaku Penuntut Umum dalam pelaksanaan pedoman tuntutan pidana.

Dalam penelitian yang dilakukan penulis mengunakan jenis penelitian hukum normatif yang merupakan penelitian yang dilakukan berdasarkan asas-asas hukum, hierarki dan hakikat hukum, sehingga sifat penelitian adalah deskriptif analitis yang memberikan gambaran dalam fenomena dengan peristiwa kebiasaan masyarakat.

Kejaksaan tidak dapat bertindak sebagai penyidik kasus-kasus khusus melainkan hanya dapat bertindak sebagai pihak yang menyetujui dimulainya penyidikan dan menerima berita acara penyidikan serta penetapan barang bukti. Upaya yang dilakukan Kejaksaan untuk menghadapi kendala dalam membuat surat dakwaan adalah mencantumkan fakta-fakta yang sama untuk setiap dakwaan yang diajukan penuntut dalam melakukan dakwaan alternatif.
PERLINDUNGAN NEGARA TERHADAP DANA SIMPANAN NASABAH PADA PERBANKAN
Authors: Shandy Utama Andrew
Published: July 2021

Bank adalah lembaga keuangan yang kegiatan usahanya yaitu menghimpun dana dari masyarakat, menyalurkan dana kepada masyarakat, dan memberikan pelayanan jasa keuangan. Salah satu kegiatan utama perbankan adalah menghimpun dana dari masyarakat dalam bentuk tabungan, deposito, dan giro. Masyarakat menyimpan dananya di bank karena percaya bahwa keamanan dananya tersebut akan jauh lebih terjamin daripada menyimpannya di dalam rumah. Menurut Kitab Undang-undang Hukum Perdata, dana nasabah yang disimpan di bank tidak termasuk ke dalam kelompok piutang yang diistimewakan apabila sebuah bank dinyatakan pailit. Permasalahan yang akan dibahas dalam penelitian ini adalah bagaimanakah perlindungan negara terhadap dana simpanan nasabah pada perbankan yang mengalami kepailitan? Metode yang digunakan dalam penelitian ini adalah penelitian hukum normatif dengan menggunakan pendekatan peraturan perundang-undangan. Sumber data yang digunakan dalam penelitian ini adalah data sekunder, yaitu data yang diperoleh dari peraturan perundang-undangan, jurnal-jurnal ilmiah, dan literatur hukum. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah studi kepustakaan. Teknik analisis data yang digunakan dalam penelitian ini adalah analisis kualitatif. Hasil dari penelitian ini adalah bahwa berdasarkan Undang-Undang Nomor 24 Tahun 2004 tentang Lembaga Penjamin Simpanan, perlindungan terhadap dana simpanan nasabah pada perbankan yang mengalami kepailitan dijamin oleh lembaga negara bernama Lembaga Penjamin Simpanan, bahkan hingga Rp2.000.000.000,- (dua miliar rupiah).
Congenital Heart Diseases in Pregnancy
Authors: Bernolian Nuswil , Radiyati Umi Partan  , Siti Nurmaini  , Cindy Kesty  , Benedictus Wicaksono Widodo
Published: July 2021

This research aims to shed light into congenital heart diseases, the pathophysiology, and the ultrasonographic findings of congenital heart diseases. Congenital heart diseases are a major health concern, affecting 1.35 million children born every year. Ventricular septal defect, atrial septal defect, and atrioventricular septal defect are found in 57.9% cases of congenital heart diseases. The risk factors include consanguineous marriage, family history of congenital heart diseases, old maternal and paternal age, and exposure to teratogens, and genetic factors. Missteps in cardiac development are the main pathophysiology of congenital heart diseases. Ultrasonography screening in 18–22 weeks gestational age is utilized to screen. Follow-up screening can increase detection rate to 80%. This study has limitation of only discussing most common congenital heart diseases and did not delve into rarer types of congenital heart diseases and did not discuss impacts or burden of congenital heart diseases in adulthood and health comorbidities associated. This literature review is beneficial for general practitioners and obstetricians focusing in maternal fetal medicine.
THE ROLE OF HYPERBARIC OXYGEN THERAPY IN FOURNIER’S GANGRENE: LITERATURE REVIEW
Authors: Giordano Vincenza , Cardillo Luca
Published: July 2021

Introduction: Fournier’s Gangrene is a severe necrotising infection that can be fatal if not recognised and treated immediately. Treatment consists of a combination of conventional therapy with a multidisciplinary approach (early diagnosis, surgical debridement, antibiotic therapy, intensive care and reconstructive surgery) and adjuvant therapy with hyperbaric oxygen therapy sessions. Objective: To identify the role and evaluate the efficacy of hyperbaric oxygen therapy in Fournier’s gangrene. Method: To conduct the following narrative review a research question was outlined using the PIO methodology. Subsequently, a literature review was conducted using the PubMed, Scopus and CINAHL Complete databases from December 2020 to February 2021. Results: Eight studies emerged from the literature review showing that the use of adjuvant Hyperbaric oxygen therapy (HBOT) in combination with classical treatment has beneficial effects and enhances the efficacy of hyperbaric oxygen therapy, resulting in lower mortality rates, in contrast to the average number of hospital days spent in intensive care, which do not undergo any significant change. But in contrast to mortality, the average number of days spent in intensive care differed significantly in favour of the standard treatment group. Conclusion: The combined effect of hyperbaric oxygen therapy with conventional therapy offers a significant advantage in the management of FG; furthermore, HBOT is associated with a significant survival advantage.
ROLE OF HYPERBILIRUBINEMIA IN PREDICTON OF GANGRENOUS/PERFORATED APPENDICITIS
Authors: Khan Irfan Hussain , Bhargava Arun
Published: July 2021

Introduction: The aim of this study was to determine the role of hyperbilirubinemia as a new diagnostic tool for predictor of gangrenous / perforated appendicitis.

Methods: Hospital based prospective study was conducted on 100 patients with perforated/gangrenous appendix

Results: In acute appendicitis case out of 84 cases 26 cases bilirubin level was more than 1mg/dl, in gangrenous appendicitis out of 3 cases all cases bilirubin level was more than 1mg/dl and in perforated appendicitis out of 13 cases 12 cases bilirubin level was more than 1mg/dl

Conclusion: It is concluded from present study that elevated total serum bilirubin without elevation of liver enzymes is a good indicator of appendicular perforation.

Keywords: Perforation, Appendicitis, Bilirubin
A Concise Review of Intellectual Disability and Puberty Problems Based on the Laws of Different Countries
Authors:   Department of Neonatology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran., Mehrpisheh Shahrokh , Memarian Azadeh ,   Department of Forensic & Legal Medicine, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran., Aghakhani Kamran ,   Department of Forensic & Legal Medicine, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Published: July 2021

Intellectual Disability (ID) is characterized by limitations in intellectual functioning and behavioral adaptations. Patients with ID have a wide range of problems affecting the quality of life in these cases and their parents, as well.
Acute Kidney Injury in Poisoned Patients Admitted to ICU
Authors:   Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, Iran., Rashidi Roghayeh
Published: July 2021

Background: Acute Kidney Injury (AKI) is an abrupt decrease in kidney function, leading to the retention of urea and other nitrogenous waste products. Poisoned patients admitted to the Intensive Care Unit (ICU) may develop AKI due to some reasons. This study was done to evaluate the AKI in poisoned patients admitted to ICU. Methods: 146 patients, admitted to the ICU of Imam Reza Hospital from March 2017 to March 2018 were studied. AKI status was assessed using Acute Kidney Injury Network (AKIN) and Risk, Injury, Failure, Loss of kidney function and End-stage kidney disease (RIFLE) classification. Data analysis was done through SPSS V. 22 software. Results: Opioids, organophosphates, aluminum phosphide, multiple drugs, and other types of poisoning were the main five poisoning classes. Opioid toxicity was had the highest frequency with 51 patients; cases in this group experienced longer length of hospitalization stay and higher serum creatinine level than others did. Among 146 patients, 19 patients (12.8%) died, and 97 patients (66%) were transferred to the ICU. Of all cases, 18 patients (12.3%) had renal dysfunction (six patients were at risk, five patient at injury, and seven patients were at failure phase based on the RIFLE criteria). Renal replacement therapy was required in 24 cases (16.4%). Conclusion: It is unlikely to detect a significant difference in the occurrence of AKI between the main poisoning classes. Being the largest group of intoxicated patients admitted to the ICU, the opioid poisoning had the highest rate of AKI
COVID-19- or Tramadol-induced Seizure: A Differential Diagnosis in Young People
Authors:   General Practitioner, Urmia Health Center, Urmia University of Medical Sciences, Urmia, Iran., Nekoueifard Solmaz , Majidi Mohammad ,   Department of Forensic Medicine and Clinical Toxicology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Published: July 2021

Coronavirus disease 2019 (COVID-19) was first declared in December 2019 from Wuhan, China [1, 2]. It then has been reported a pandemic in March 2020 by the World Health Organization [3]. Clinical features of COVID-19 are different from asymptomatic to mild to moderate symptoms, such as fever, headache, myalgia, sore throat, anosmia, cough, fatigue headache, hemoptysis, and dyspnea to the life-threatening complications, including shock, pneumonia, acute respiratory distress syndrome, myocarditis, myocardial infarction, acute kidney injury, multi-organ failure, and even death [1, 2].
Cardiovascular Conditions in Patients With Aluminum Phosphide Poisoning
Authors:   Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Ataei Zahra , Dadpour Bita ,   Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Alizadeh Anahita ,   Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran, Mousavi Seyed Reza ,   Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Moshiri Mohammad ,   Medical Toxicology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran., Sheikhveisi Zahra ,   Department of Medical Toxicology, Emam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran., Banaye Yazdipour Alireza ,   Department of Health Information Management, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran.
Published: July 2021

Background: Aluminum Phosphide (AlP) is a well-known rodenticide and insecticide, used as a fumigant to control pests and rodents in grain-storage facilities. Its intoxication presents a medical emergency that requires early rigorous management. This study aimed to investigate cardiac function by Electrocardiogram (ECG) changes in patients with AlP intoxication. We also explored the potential relationship between low bicarbonate and cardiac function. Methods: This cross-sectional study investigated 42 patients in the age range of 17-47 years, with a history of orally-administered AlP poisoning, known as “rice tablet”, admitted to the toxicology ward of Imam Reza Hospital from March 2019 to March 2021. The study patients’ demographic data were collected by trained interviewers, using pretested questionnaires. Systolic and diastolic blood pressure, as well as blood samples, were measured 12 hours from admission. Echocardiography was performed during the first 12 hours and on the fifth-day post-admission. All statistical analysis was performed using R 3.6.1. The significance level was set at 0.05 for all statistical tests. Results: In total, 48.78% of patients presented normal bicarbonate levels, and 24.39% and 26.83% had moderate and severe acidity, respectively. Moderately and severely decreased Left Ventricular Ejection Fraction (LVEF) was observed among 21 (51.2%) and 10 (24.4%) patients, respectively. Furthermore, mild Right Ventricular (RV) function was observed among 11 (26.8%) patients. A statistically significant association was observed between bicarbonate level and RV function (P<0.001) and LVEF (P<0.001). Besides, 19.5% of the explored patients expired. The proportion of expired patients was significantly higher in patients with mild RV function, compared to the other patients (P<0.001). Conclusion: Acute AlP intoxication is a worldwide serious problem. Severe metabolic acidosis and ECG abnormalities are associated with poor outcomes in this respect. Thus, conducting early ECG and echocardiography could be desirable instruments to predict prognosis. There is no antidote for AlP poisoning; thus, the replacement of a safer agent for in-store grain protection is strongly suggested.
Successful Treatment of Acute Aluminum Phosphide Poisoning by Aloe Vera Syrup: A Case Report
Authors:   Department of Internal Medicine, School of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran., Shakeri Masihallah , Soroosh Davood ,   Department of Internal Medicine, School of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran, Shakeri Heshmatollah ,   Department of Internal Medicine, School of Medicine, Jahrom University of Medical Sciences, Jahrom, Iran., Kalani Navid ,   Research Center for Social Determinants of Health, Jahrom University of Medical Sciences, Jahrom, Iran., Hatami Naser ,   Student Research Committee, Jahrom University of Medical Sciences, Jahrom, Iran., Foroughian Mahdi ,   Department of Emergency Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Published: July 2021

Background: Aluminum phosphide, known as rice pill in Iran, is a very effective pesticide for commercial and industrial ‎use. The high lethality of Aluminum phosphide is due to Phosphine gas (PH3) which is released by its ‎reaction with water. One of the most important properties of aluminum phosphide, which despite being ‎very lethal to almost all living creatures, still makes it one of the most widely used pesticides, is its very ‎high yield, ease of use, and, most importantly, the absence of residues in products after application; while ‎its exposure to the human body is associated with high mortality.‎ Case Presentation: In this article, we reported the successful treatment of rice pill-induced poisoning in a 30-year-old man using a novel approach. Accordingly, we used sodium bicarbonate (50 ccs) and aloe vera syrup (1-2 L), followed by olive oil (150 cc olive oil was given every 2 hours). Conclusion: While numerous studies recommend observing patient conditions as the treatment approach, our presented case was a successful experience of treating acute aluminum phosphide poisoning.
Comparison of the Childhood Trauma, Mindfulness Attention Awareness and Integrative Self Knowledge in Cancer Patients and General Population
Authors:   Department of Counseling, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran., Khanjani Mohammad Saeed , Mosavat Shadan ,   Department of Counseling, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran., Bbahmani Bahman ,   Department of Counseling, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran., Bakhshi Enayatollah ,   Department of Statistics, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Published: July 2021

Objectives: This study aims to compare childhood trauma, integrative self-knowledge and mindfulness in patients with cancer and healthy people. Methods: This descriptive-analytical study was conducted on 139 patients with cancer and 139 healthy people referred to Firoozgar Hospital and SAMAR Charity House who were selected by a convenience sampling method. They were asked to complete Integrative Self-Knowledge (ISK) Questionnaire, Childhood Trauma Questionnaire (CTQ) and Mindfulness Attention Awareness Scale (MAAS). Data were analyzed using descriptive and inferential statistic methods including MANOVA. Results: There was a significant difference between patients and controls in terms of ISK (P<0.001), mindfulness (P<0.001) and childhood trauma (P<0.001). Conclusion: Cancer patients have lower ISK and mindfulness but higher childhood trauma compared to healthy people. Attention should be paid to the role of these factors in prevention and treatment processes.
IoT Smart Energy Meter Monitoring with Web and Blynk App
Authors: Patel Arpanbhai , Darji Dhwani
Published: July 2021

Electricity is a crucial innovation that would render life on Earth impossible. As a result, there is a clear requirement to track the amount of power used. The wattmeter does this, but a GEB representative must visit each customer's home to evaluate power use and estimate the bill amount. As a result, it entails a lot of physical labor and takes time. We planned to build an IoT-based energy meter for each of GEB's customers. As a result, the suggested energy meter monitors the amount of power utilized and uploads it to the Thingspeak cloud, where the reading may be viewed by the person concerned. ESP 8266, a Wi-Fi module, can be used to send the power reading to the cloud. The opt coupler analyzes the power reading from the digital wattmeter and feeds it digitally to the Arduino. As a way, it uses IoT to automate the process of measuring energy usage at households, allowing remote access and digitalization for each GEB subscriber.
Evaluación de la gestión de continuidad de los servicios: Universidad de Costa Rica, Sede de Occidente
Authors: Campos Pérez Lisa , Esquivel Ariaas Jorge , Varela Rojas Daniela
Published: July 2021

La Universidad de Costa Rica (UCR) es una de las cinco universidades públicas de la República de Costa Rica, la Sede de Occidente (UCR-SO) fue la primera sede regional de la UCR, fundada en 1968. En los últimos años se ha visto afectado el desarrollo de las actividades universitarias y el uso de sus instalaciones debido a fenómenos de diferente naturaleza que han afectado a la institución. El documento tiene como propósito evaluar el nivel de desarrollo de las estrategias de continuidad de la UCR-SO, mediante el análisis de los sistemas de gestión de riesgos y continuidad de los servicios esenciales de la institución, a través de la auditoría de cinco normas internacionales y factores internos, con lo cual se busca identificar oportunidades de mejora en relación con la continuidad institucional de la UCR-SO. Se obtuvo como resultado el poco desarrollo de los sistemas de gestión evaluados y la necesidad que presenta la institución de generar e integrar un modelo que asegure la prestación oportuna y de calidad de esos servicios, especialmente los catalogados como esenciales por su incidencia en el desarrollo educativo, social e investigativo; así como en el funcionamiento efectivo de la institución.
Impacto Da Gestão Da Tecnologia Na Qualidade De Vida De Estudantes: Estudo De Caso Em Escolas Técnicas Do Estado De São Paulo
Authors: Ramirez Alejandro Lynn Pereira , Santos Fabiano Marcelo dos , Geraldi Luciana Maura Aquaroni
Published: July 2021

Esta pesquisa teve como objetivo analisar como a gestão da tecnologia contribui para a melhora da qualidade de vida de alunos das escolas do ensino técnico na cidade de São Paulo em conformidade com uma das metas estabelecidas pela ONU (Organização das Nações Unidas) que promove vida saudável e bem-estar para as pessoas do mundo. A pergunta que direcionou a pesquisa foi: é possível que a Gestão da Tecnologia melhore a qualidade de vida de alunos durante uma crise sanitária? A relevância desta pesquisa está nas informações obtidas sobre a percepção de melhora da qualidade de vida de alunos pela efetiva gestão dos recursos tecnológicos no período da crise sanitário-econômica em 2020 e pela verificação da possibilidade de continuação da modalidade remota no ensino técnico após a pandemia. A pesquisa foi qualitativa e o fenômeno da gestão de tecnologia que leva à qualidade de vida foi observado com a utilização do estudo de caso de escolas de ensino técnico (ETEC) na cidade de São Paulo – Brasil. Verificamos que a Gestão da Tecnologia leva à Qualidade de Vida, no entanto, os alunos não têm consciência de que a possibilidade de uma carreira, crescimento pessoal e perspectiva de avanço na vida profissional são indicadores de melhora na qualidade de vida.
Analyse wichtiger vorbestehender Risikofaktoren bei Patienten mit COVID-19-Diagnose in Amapá, Amazônia, Brasilien
Authors: Oliveira Arthur Aires de , Moreira Danilo José Silva , Pimentel Jhon Allyson Sena , Costa Pedro Henrique de Magalhães , Dias Claudio Alberto Gellis de Mattos , Araújo Maria Helena Mendonça de , Oliveira Euzébio de , Dendasck Carla Viana , Souza Keulle Oliveira da , Fecury Amanda Alves
Published: July 2021

COVID-19 (Coronavirus Disease 2019) ist eine Infektion, die durch das SARS-CoV-2-Virus verursacht wird, wobei erste Fälle im Dezember 2019 in Wuhan City gemeldet wurden. Es wurde festgestellt, dass bei Patienten mit Komorbiditäten ein höheres Risiko für Komplikationen und Sterblichkeit im Falle einer Infektion besteht. Die Krankheit wurde von der Weltgesundheitsorganisation im Jahr 2020 als Gesundheitsnotstand betrachtet, und in Brasilien führte das Gesundheitsministerium Maßnahmen zur epidemiologischen Überwachung von Fällen durch, die in den verschiedenen Föderativen Einheiten des Landes registriert wurden. Unter diesen geht Amapá a von einer hohen Inzidenz und Sterblichkeit aus. Diese Studie zielt darauf ab, die wichtigsten früheren Risikofaktoren bei Patienten mit COVID-19 im Bundesstaat Amapá zu analysieren. Dazu wurden die im Coronavirus-Amapá-Panel verfügbaren Sekundärdaten durch eine am 22. Mai 2020 durchgeführte Suche verwendet. Auf der Plattform wurden Daten über die Anzahl der Patienten mit COVID-19 diagnostiziert, sowie die Anzahl der Todesfälle aufgrund der Krankheit, mit einer gemeinsamen Bewertung in jedem Thema der Komorbiditäten gefunden. Nach dem Gruppieren dieser Daten in Microsoft Excel-Tabellen wurde eine quantitative und beschreibende Analyse dieser Daten durchgeführt. Im Staat wurden bis zum Tag der Abholung insgesamt 28.927 Patienten mit COVID-19 diagnostiziert. Etwa 1,31 % (378 Fälle) hatten einen Risikofaktor, der sie anfällig für Komplikationen infolge von COVID-19 entwickeln konnte, wobei Diabetes und chronische Herzerkrankungen die Bedingungen mit der höchsten Anzahl von Datensätzen waren. Noch im Bundesstaat Amapá wurden 420 Todesfälle bei Patienten mit COVID-19 festgestellt. Davon hatten 75,71 % (318 Fälle) zuvor Risikofaktoren für ein höheres Risiko für Komplikationen aufgrund von COVID-19, wobei Bluthochdruck und Diabetes die vorherrschenden Erkrankungen waren. Mit der Studie wurde in Amapá festgestellt, dass ein großer Teil der Bevölkerung von Patienten, die mit der Krankheit diagnostiziert wurden und die starben, eine Vorgeschichte von Risikofaktor für COVID-19 hatte. Aufgrund der Meldung von Risikofaktoren in der Todessituation, die nicht in der Anzahl der diagnostizierten Patienten erfasst wurden, sowie der Unspezifität, die dem Zustand der Patienten innewohnt, die durch die staatlichen Gesundheitsmechanismen überwacht werden, war es nicht möglich, eine detailliertere Analyse über den Grad der Komplikation und der Letalitätsrate durchzuführen, die durch einen bestimmten Risikofaktor und seine Assoziation mit einer Coronavirus-Infektion erzeugt wird.
Telaah Konstruktivis Partisipasi Cina dalam the Campaign to Stop Killer Robots
Authors: Waluyo Bambang dwi , Fahd Ryan Muhammad
Published: July 2021

Studi ini mencoba menjelaskan motivasi Cina atas keterlebitannya dalam the Campaign to Stop Killer Robots meskpiun dalam waktu yang bersamaan terus mengembangkan senjata otonom mematikan. Studi ini mempergunakan konsep Transformasi Militer dari Martin van Creveld untuk mempertegas signifikansi LAWS dan jga  teori Interstitial Conception of Politics dari Christian Reus-Smit untuk menganalisis motivasi Cina. Teori ini menjelaskan bahwa setiap tindakan politik pasti ditentukan oleh empat elemen yakni: (1) ideografis (2) etis (3) purposif, dan (4) instrumental.Artikel ini menemukan bahwa motivasi utama keterlibatan Cina adalah (1) untuk mempertahankan diskursus “the peaceful rise of China”, dan (2) untuk mengerem Amerika Serikat, kompetitor utama Cina dalam teknologi LAWS.
KEPENTINGAN CINA DALAM PEMBANGUNAN PANGKALAN MILITER DI DJIBOUTI PADA TAHUN 2016
Authors: Darmawan Arif , Widya Ningsih Intan
Published: July 2021

China is not only the most populated country in the world. China's success is so rapidly, especially in the economic field that China so overwhelmed many countries. Entering a new chapter in the 21st century is not only focused on economic, China then renewed its defense policy to strengthen China's sovereignty and achieve its national interests. One of China's strategies was to build its first military base in Djibouti, Africa, in 2016 then. It was a new history for China in its military field. This study aims to analyze the intentions and objectives of China that built its military base in Djibouti using the neorealist theory of Kenneth Waltz. The focus of this research lead to the China’s military base that grown from some factors and the effect on the global order.
Employee Engagement and Organizational Performance
Authors: Akanpaadgi Emmanuel , Binpimbu Felicia
Published: July 2021

This study sought to find out the extent of employee engagement in the public sector in Ghana using the Upper East Regional Health Directorate as a case study. The survey method was employed in the study. Close-ended and Likert-Scaled questionnaires were administered to participants to generate the data. Descriptive statistics were used to analyze the demographic data while the Relative Importance Index (RII) was used to analyze the scaled responses using the equation: RII= Σ???? / (???? × ????). The figures obtained confirmed the positive relationship between employee engagement and organizational performance. The good performance of the Upper East Regional Health Directorate was found to be influenced by the effective engagement of the staff.
In use stability of chemical anticancer drugs and biologics
Authors: Astier A.
Published: July 2021

Background. For hospital pharmacists and nurses it is critical to have real data about the stability of injectable drugs in practical situations: opened drug formulation, after the reconstitution of lyophilized production or after the dilution in various vehicles. Unfortunately, these data are seldom available. The manufacturer’s stability data are usually quoted as “stable for 24 hours at 4 °C” not for the true reasons, but considering the possible bacterial contamination or due to the fact that stability tests were only conducted during a very short period. This problem is of paramount importance for therapeutic proteins, mainly monoclonal antibodies, because the latter are very expensive.

Objective. To define the in use stability of anticancer drugs.

Materials and methods. Analysis of literature data on this topic; own study on diluted rituximab stability.

Results and discussion. Biologic drugs have revolutionized the treatment and prevention of many debilitating and life-threatening diseases. Biologics are much bigger and have a much more complicated structure than classical drugs. Principal causes of biologics’ instability include temperature changes, dilution, absorption, oxidation, shaking and shearing etc. Protein instability can be divided into physical and chemical instability. The former includes aggregation, denaturation and absorption on surfaces, and the latter – desamidation, disulfide bonds breakage and formation, oxidation, hydrolysis, isomerization, non-disulfide cross-linking, and deglycosylation. Instability of anticancer drugs and biologicals can lead to their toxicity, immunogenicity and efficacy loss. Instability can be overcome by the centralization of pharmacy handling, but firstly it needs to be thoroughly studied with the help of modern methods. The own study has revealed that the diluted rituximab is stable up to 6 months in polyolefin bags stored at 4 or 22 °C. The preparations can be realized without any problems. There also no fear of instability in case of thermal excursions. Such findings if introduced in practice can save about 150,000 euros a year.

Conclusions. 1. In-use analysis of proteins requires several methods. 2. Instabilities are divided into physical and chemical. 3. Aggregation is an initial response to any stress and must be completely eliminated.