bluuebunny/crossref_metadata_2025 huggingface dataset:
Meningismus in IgA vasculitis (Henoch–Schönlein purpura)
Authors:   Department of Paediatric Internal Medicine and Allergology, 3rd Department of Paediatrics, Medical University of Lodz, Łódź, Poland. Head: Associate Professor Joanna Jerzyńska, MD, PhD, Gmachowska Katarzyna
Published: January 2021

IgA vasculitis is the most common acute systemic vasculitis in children. Typical symptoms include cutaneous purpura not associated with thrombocytopenia, acute-onset abdominal pain, arthritis, renal symptoms and, less commonly, neurological symptoms. The disease is usually mild and self-limiting. Although the aetiology of IgA vasculitis is unknown, autoimmune involvement is suspected. Symptomatic treatment is mainly used; therapeutic method that would reduce disease duration and prevent recurrence is unknown. Meningococcal sepsis should always be ruled out in a child with cutaneous purpura. We present a case of a 4-year-old boy with IgA vasculitis who developed symptoms of meningeal irritation.
Never fish your brother: a case of plastic fish hook in the oesophagus
Authors:   Department of Otorhinolaryngology – Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kota Bharu, Kelantan, Malaysia, Nasir Mohd Shaiful Nizam Mamat , Draman Wan Nur Anis Wan ,   Department of Otorhinolaryngology – Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kota Bharu, Kelantan, Malaysia, Mohamad Sakinah ,   Department of Otorhinolaryngology – Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kota Bharu, Kelantan, Malaysia, Hamid Suzina Sheikh Ab ,   Department of Otorhinolaryngology – Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kota Bharu, Kelantan, Malaysia, Mohamad Irfan ,   Department of Otorhinolaryngology – Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kota Bharu, Kelantan, Malaysia
Published: January 2021

Foreign body ingestion is a common, yet sometimes dangerous entity encountered in paediatric population. Depending on the type, size and location of a foreign body, it can present with variety of symptoms. The purpose of this report is to present an unexpected radiolucent oesophageal foreign body impaction in a 4-year-old boy missed by imaging, but successfully removed using rigid esophagoscopy without any complications.
Unexpected nasal foreign body
Authors:   Department of Otorhinolaryngology – Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kota Bharu, Kelantan, Malaysia, Ehdam Vshakri , Hamid Suzina Sheikh Ab ,   Department of Otorhinolaryngology – Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kota Bharu, Kelantan, Malaysia
Published: January 2021

Foreign body in the nose is a common complaint in the paediatric age group and the most prevalent site of foreign body insertion compared to the ear and throat. Typical presentation involves foul-smelling unilateral nasal discharge. However, some cases are asymptomatic with no witnesses, and only discovered by medical practitioners during routine examinations. The diagnosis in this scenario becomes more challenging when another nasal pathology is present. We describe the case of a 6-year-old girl with underlying extensive infantile haemangioma of the face, tongue, neck and chest, who came for a routine follow-up, without any nasal complaints. However, the examination revealed right nasal crusting with bluish discoloration and hypertrophy of the right inferior turbinate, which was initially thought of as extension of the patient’s haemangioma. A foreign body in the right nasal cavity was noted by the girl’s parent on the next day after nasal douching, and was successfully removed in the clinical setting.
Bilateral Single-Stage Nephrectomy for Synchronous Bilateral Renal Cell Carcinoma
Authors: Kotb Ahmed , Alaref Amer , Kisselgoff David , Ismail Asmaa , Rozenberg Radu , Burute Nishigandha , Shahrour Walid , Prowse Owen , Elmanasy Hazem
Published: January 2021

Bilateral synchronous renal cell carcinoma (RCC) is uncommonly encountered. Debate exists among urologists in managing these cases in a single surgery versus staged surgeries. We aim to report our experience in managing encountered cases using single-stage surgeries. Retrospective collection of cases with pathologically confirmed RCC that had single-stage bilateral renal surgery over the past 2 years. Three cases were identified. Patients were managed using bilateral transverse lateral lumbotomy. All patients did not have intraoperative or postoperative complications. Kidney function stayed stable after surgery. Single-stage bilateral renal surgery is a safe procedure. Bilateral transverse lateral lumbotomy allows for a fast and safe surgery with minimal complications. There is a possible histological dis-concordance in bilateral synchronous RCC.
An Efficient Hybrid Method for Solving Security-Constrained Optimal Power Flow Problem
Authors:   Department of Power Delivery, Ho Chi Minh City University of Technology (HCMUT), 268 Ly Thuong Kiet Street, District 10, Ho Chi Minh City, Vietnam, Minh Le Phuong , Duong Thanh Long ,   Faculty of Electrical Engineering Technology, Industrial University of Ho Chi Minh City, 12 Nguyen Van Bao Street, Go Vap District, Ho Chi Minh City, Vietnam, Ngoc Vo Dieu ,   Vietnam National University Ho Chi Minh City, Linh Trung Ward, Thu Duc District, Ho Chi Minh City, Vietnam, Thanh Le Tung ,   Department of Electrical and Electronic Engineering, Tra Vinh University, 126 Nguyen Thien Thanh Street, Tra Vinh City, Tra Vinh Province, Nguyen Sy Quoc ,   Tra Vinh Vocational College, Vinh Yen Hamlet, Long Duc Commune, Tra Vinh City, Tra Vinh province, Vietnam
Published: January 2021

The optimal operation for different states such as normal and contingency cases of a power system has a very important role in the operation. Therefore, it is necessary to analyze contingencies in the system so as the most severe cases should be considered for integrating into the optimal power flow (OPF) problem and the security-constrained optimal power flow (SCOPF) becomes an important problem for considering in the power system operation. This paper proposes a combined pseudo-gradient based particle swarm optimization with constriction factor (PGPSO) and the differential evolution (DE) method for solving the SCOPF problem. The PGPSO-DE method is a newly developed method for utilizing the advantages of the pseudogradient guided PSO method with a constriction factor and the DE method. The proposed PGPSO-DE has been tested on the IEEE 30 bus system for the normal case and the contingency case with two types of the objective function. The results yielded from the proposed method have been validated via comparing to those from the conventional PSO, DE, and other methods reported in the literature. The comparisons for the results obtained from the proposed PGPSODE method have shown that it is very effective to solve the large-scale and complex SCOPF problem.
Application of BARON Solver for Solution of Cost Based Unit Commitment Problem
Authors:   Electrical Engineering Department National Institute of Technology Hamirpur, India, Kumar Vineet , Naresh R ,   Electrical Engineering Department National Institute of Technology Hamirpur, India
Published: January 2021

This paper presents the solution to cost-based unit commitment (CBUC) problem with and without ramp rate limits of thermal power plants using general algebraic modelling system (GAMS) with BARON solver. The BARON solver in GAMS environment takes care of different units and system constraints to find an optimal solution. To validate the effectiveness of the proposed GAMS solution, simulations have been performed on six different systems consisting of 10-units, 20-units, 40-units, 60-units, 80-units and 100-units, respectively. The analysis also includes the valve-point loading along with the ramp rate limits of thermal units. Results obtained with BARON solver in GAMS have been compared with other approaches available in literature. Comparative analysis shows that the performance of GAMS is better as compared to other existing techniques in terms of operating cost obtained and satisfaction level of constraints.
СУЩНОСТЬ СОЦИО-ЭКОЛОГО-ЭКОНОМИЧЕСКИХ СИСТЕМ В ПРОЦЕССЕ ФОРМИРОВАНИЯ УСТОЙЧИВОГО ИСПОЛЬЗОВАНИЯ ЗЕМЕЛЬНЫХ РЕСУРСОВ
Authors: Долматова Людмила Георгиевна , Петрова Ирина Альбертовна
Published: January 2021

В статье рассмотрены основные положения устойчивого развития социо-эколого-экономических систем, их взаимосвязь с внутренними и внешними условиями в процессе использования земельных ресурсов. Проанализированы основные показатели и критерии, характеризующие эффективность их использования.
АНАЛИЗ МЕТОДОВ УПРАВЛЕНИЯ КАЧЕСТВОМ ЭНЕРГОСБЕРЕГАЮЩИХ ПРОЦЕССОВ ПРОМЫШЛЕННОГО ПРЕДПРИЯТИЯ
Authors: Лагутина Ольга Николаевна
Published: January 2021

Проанализирована методологическая база управления качеством в энергосбережении. Рассмотрены международные стандарты систем энергетического менеджмента. Предложены подходы к модификации цикла совершенствования энергосберегающей политики предприятия.
СОСТОЯНИЕ И НАПРАВЛЕНИЯ РАЗВИТИЯ ТЕОРИИ ЭКОНОМИКИ И УПРАВЛЕНИЯ ЭЛЕКТРОЭНЕРГЕТИЧЕСКИМ КОМПЛЕКСОМ РОССИИ
Authors: Булатенко Мария Андреевна , Тульчинская Яна Ильинична
Published: January 2021

В статье анализируются научные работы, направленные на развитие теории и практики управления организациями электроэнергетического комплекса (ЭЭК) РФ в условиях развития конкурентных отношений на энергорынках. Обнаружена взаимосвязь между объектами исследования и уровнем собственного энергопотребления функциональных составляющих ЕЭС России. Выявлена актуальность дальнейшего развития управленческих инноваций в области энергосбережения и повышения энергетической эффективности и построения систем энергетического менеджмента для ЭЭК.
ПОВЫШЕНИЕ КАЧЕСТВА ЖИЗНИ РОССИЙСКИХ ГРАЖДАН ― ПРИОРИТЕТНОЕ НАПРАВЛЕНИЕ ОБЕСПЕЧЕНИЯ ЭКОНОМИЧЕСКОЙ БЕЗОПАСНОСТИ
Authors: Курепина Наталья Леонидовна , Барков Сергей Сергеевич
Published: January 2021

В статье приведены данные об уровне и качестве жизни российских граждан, которые свидетельствуют о существующей потребности в обеспечении безопасности в целях снижения возможности негативного воздействия, повышения качества жизненных условий. Отмечено, что необходимо повысить уровень контроля качества продуктов питания.
The Effects of Argumentation-Based Teaching Approach on Students’ Critical Thinking Disposition and Argumentation Skills: “Population in Our Country Unit”
Authors: Akbaş Yavuz
Published: January 2021

As there are limited studies examining relationships between argumentation-based teaching approach and critical thinking and argumentation skills  in social studies, the aim of this study was to examine the effects of argumentation-based teaching approach on students' critical thinking disposition and argumentation skills, and the relationship between students’ argumentation skills and critical thinking disposition. We used a quasi-experimental design with pretest-posttest equivalent control groups. The participants of this study were 94 seventh grade students from three different classrooms in a middle school in Erzurum district of Turkey. We utilized University of Florida Engagement, Maturity and Innovativeness Critical Thinking Disposition Instrument (UF/EMICTDI) to identify students’ critical thinking disposition and argumentation activities to document students’ argumentation skills. We used one-way ANOVA and multiple comparisons Tukey tests to analyze the data obtained via the UF/EMICTDI, correlation and regression analysis to investigate the relationships between students’ argumentation skills and critical thinking disposition. Argumentation Evaluation Rubric was used in order to evaluate the arguments that the students formed. Results showed that there was no statistically significant difference between students’ pre-test critical thinking disposition scores in the experimental and control groups but there was a statistically significant difference between students’ post-test critical thinking disposition scores. Additionally, we observed that students’ argumentation skills enhanced throughout the study, there was a statistically significant positive relationship between students’ argumentation skills and critical thinking disposition, and argumentation skills variable was the predictor of critical thinking disposition. We recommend future research studies to examine the effects of the argumentation-based science learning approach on different higher-order thinking skills. Additionally, in social studies classes, similar activities employed in this study on “Population in Our Country” unit can be used in teaching different topics/units in order to improve students’ argumentation skills.
Cinderella Syndrome "Women with Fear of Independence": Developing a Scale
Authors: Vural Meryem , DEMİR Melek
Published: January 2021

Cinderella syndrome is a concept which is used to define woman who fear from being independent. Women with Cinderella syndrome are in the need of men’s refuge and protection. The syndrome is like a psychological dependence for women and in this dependence, situation being patient and moral is important for being rescued by a man as a reward.  In the syndrome women expect a man to come and take control of their own lives so that they can live happily. The aim of the study developing a scale into Turkish culture to determine the level of Cinderella Syndrome in females. The Cinderella Syndrome Scale is a 5-point Likert Type scale which includes 25 items. Exploratory factor analysis (EFA) was conducted to define construct validity and three factors were determined, called “sexist attitude”, “escape from responsibility” and “quitting career”. According to EFA, three factors describe 54,69 % of the variance. Results of EFA were validated by confirmatory factor analysis (CFA). The Cronbach’s alpha was found as .94 for the total scale.
The Metaphoric Perceptions of the Prospective Turkish Language and Literature Teachers, Taking Pedagogical Formation Education about “Bilingualism”
Authors: Günaydın Yusuf
Published: January 2021

The concept of bilingualism is gaining prominence in our daily lives due to political and social reasons. The fact that bilingualism has become an undeniable fact requires investigation of it in educational sciences. How prospective teachers perceive the concept of bilingualism will fill a gap in the literature in terms of understanding educational practices. In this context, the purpose of this study is to determine the perceptions of the Turkish language and literature teacher candidates who have received formation education about the concept of "bilingualism" through metaphors. About 92 Turkish language and literature teacher candidates, studying at Çukurova University, form the research group of the study, for which qualitative research design is adopted. As a data collection tool, each student was given a guidance note with the expression of “bilingualism is like… because…” and the blanks in this guidance note were asked to be filled in. The metaphors obtained in the study were collected in different categories. Content analysis technique was used to analyze the data. According to the results of the research, it was determined that Turkish language and literature teacher candidates who received formation education had positive perceptions about the concept of bilingualism in a total of 12 concept categories.
Analisis Indeks Kelelahan dan Daya Tahan Anaerobic Atlet Futsal SMA Institut Indonesia Semarang
Authors: Wibisana Muh. Isna Nurdin
Published: January 2021

While futsal is a pre dominant anaerobic endurance sport. Problem research of how the anaerobic endurance ability o extracurricular participants at the Semarang Indonesia Institute High School. The purpose of this study was to determine the anaerobic endurance of extracurricular participants at the Semarang Indonesia Institute High School.This research method uses a descriptive qualitative survey research design. The sample consisted of 16 male students participating in the extracurricular at the Semarang Indonesia Institute High School. The research instrument used the RAST (Running Anaerobic Sprint Test).The result of the study are based on the RAST Test. The test result show that the sample that has an index of fatigue is said to be tired as many as 12 samples (75%) while the samples that have said to be tired are as many as 4 samples (25%). An athlete’s physical condition can be predicted using the right test instrument.Based on data analysis and discussion, it can be concluded that the fatigur index an anaerobic endurance ability of futsal extracurricular participants at the Indonesia Institute of High School Semarang is tired. Test recommendations or endurance testing for futsal sports using Running Anaerobic Sprint Test (RAST)
Pengaruh Senam Aerobik dan Motivasi Latihan Terhadap Penurunan Persentase Lemak Tubuh
Authors: Rifki Muhamad Sazeli , Nuarye Indah Putri , Welis Wilda , Abbas Syamsuar
Published: January 2021

The purpose of this study was to determine the effect of aerobic exercise and motivation on decreasing body fat percentage of members of the D'Ladies Gymnastics Gymnastics Padang. This type of research is an experiment with a factorial design By Level 2 x 2. The sample was drawn using purposive sampling technique, so that the sample amounted to 40 people with criteria aged 20-30 years. Body fat instrument using Body Fat Analyzer and training motivation using Likert scale model questionnaire. Data were analyzed using ANOVA 2 x 2 and Tukey's follow-up test at α = 0.05. The results of hypothesis testing show, (1) there is a difference in the effect of Mixed Impact aerobic exercise and Low Impact aerobic exercise on decreasing body fat percentage, (2) there is an interaction between aerobic exercise and motivation on decreasing body fat percentage, (3) there is a difference in effect. Mixed Impact aerobic exercise and Low Impact aerobic exercise seen from high training motivation, and (4) there is no difference in the effect of Mixed Impact aerobic exercise and Low Impact aerobic exercise seen from low training motivation. It can be concluded that Mixed Impact aerobic exercise is better than Low Impact aerobic exercise in reducing body fat percentage when seen from high training motivation. As for low exercise motivation, both treatments can be given to decrease the percentage of body fat
Regulating the Urban Commons: A Romanian Case Study of Improving Building Facades
Authors: Vrabie Anamaria , Ianole-Călin Rodica
Published: January 2021

This paper examines the effect of build environment regulations for facades emergency repairs and embellishment, as implemented by the city of Cluj-Napoca, the second largest municipality in Romania. The scope was to identify to what extent the over taxation measure was efficient in generating compliant behaviour and what secondary effects it may have generated in people’s attitude towards the local authorities. We conducted structured interviews with 25 homeowners targeted by the policy. The qualitative analysis uncovers structural issues on how the policy was implemented and communicated to the population. It further acknowledges difficulties in managing mixed property and collective actions. We interpret the findings as a first step towards building a more comprehensive research framework focused also on included behavioural insights, as captured by our recommendations. Namely, they illustrate that homeowners were critical about the measure, both in its rationale and its implementation, and were unable to act upon a cost-benefit analysis given the ambiguous available information. The findings further acknowledge difficulties in managing mixed property and collective actions, but they also hint favourably towards the role of peer effects, expressed here as compliant neighbours’ behaviour. We interpret the results of this exploratory case study as a first step towards building a more comprehensive approach to serve as a toolkit in examining the development of innovative local policies in post-communist environments, through a combined research framework including also the significant contribution of behavioural insights, next to the traditional rational actor theories. Naturally, the usual limitations of the method also apply to our study, in the sense of non-generalizable conclusions. This fuels up the need for further research on similar regional and urban challenges in an extended multiple-case study scheme.
A Soft Systems Methodology for Business Creation: The Lost World at Tyseley, Birmingham
Authors: Cavada Marianna , Bouch Chris , Rogers Chris , Grace Michael , Robertson Alexander
Published: January 2021

Much has been written about the benefits of green infrastructure, but securing the resources necessary for its development and long-term maintenance is often difficult. This article’s premise is that, in general, people and organisations will take action to provide those resources when they can see value accruing to them; therefore narratives of value generation and capture (our definition of business models) are required to motivate and support that action. This article explores the application of soft systems methodology to the wicked problem of business model development in the context of a social enterprise, using a case study based on a piece of green infrastructure in the city of Birmingham, UK, called The Lost World. The research involved a workshop with several of The Lost World’s key stakeholders and aimed at identifying: The Lost World’s scope as a business; its potential value streams; and how they might be realised in a social enterprise. Analysis of the findings shows that while stakeholders can identify opportunities for their organisations, bringing those opportunities to fruition is difficult. The research demonstrates a compelling need for social entrepreneurs to act as catalysts and long-term enablers of the formulation and maintenance of businesses and business models—vital missing actors in the ambition to transform cityscapes.
Interleukin 6 in aging and age­-related diseases
Authors: Topolyanskaya S. V.
Published: January 2021

Modern concepts about the importance of subclinical inflammation in various age-associated pathology are described in the review. The term “inflammaging” (inflammation due to aging) refers to the special role of inflammation in the aging processes. This type of inflammation is low-grade, controlled, asymptomatic, chronic and systemic. Inflammaging determines the rate of aging and life expectancy. The balance of pro-inflammatory and anti-inflammatory cytokines plays a significant role in aging processes. The increased levels of pro-inflammatory cytokines such as interleukin-6 and tumor necrosis factor-α in the elderly are associated with different diseases, disability and mortality. Interleukin-6 is a multifunctional cytokine involved in the regulation of acute phase response and other immunological reactions, in the hematopoiesis and in chronic inflammation. This cytokine is important in the pathogenesis of chronic inflammation diseases, as well as different oncological disorders. Interleukin-6 is often called the “cytokine of gerontologists”, since it is one of the main signaling pathways associated with aging and age-related diseases. This cytokine also plays an important role in the pathogenesis of atherosclerosis, coronary artery disease, chronic heart failure and increases the risk of death from cardiovascular diseases and overall mortality. Interleukin-6 is a key proinflammatory cytokine responsible for the “metabolic inflammation”, obesity, insulin resistance and diabetes mellitus. This cytokine has a significant impact on the development of sarcopenia and frailty. The serum levels of interleukin-6 negatively correlate with muscle mass and skeletal muscle function in the elderly, so it is considered as a biomarker of sarcopenia and functional decline. Interleukin-6 may contribute to the development of osteoporosis by stimulating osteoclastogenesis and bone resorption. The modern data indicate the diverse effects of interleukin-6 and confirm the significant role of this cytokine in aging and in different age-associated pathology.
Polyphase deformation along the South Bohemian Batholith-Moldanubian nappes boundary – The Freyenstein Fault System (Bohemian Massif/Austria)
Authors: Griesmeier Gerit E. U. , Iglseder Christoph , Schuster Ralf , Petrakakis Konstantin
Published: January 2021

This work describes the Freyenstein Fault System, which extends over 45 km in the southeastern part of the Bohemian Massif (Lower Austria). It represents a ductile shear zone overprinted by a brittle fault located at the eastern edge of the South Bohemian Batholith towards the Moldanubian nappes. It affects Weinsberg- and a more “fine-grained” granite, interlayered aplitic granite and pegmatite dikes as well as paragneiss of the Ostrong Nappe System. The ductile shear zone is represented by approximately 500 m thick greenschist-facies mylonite dipping about 60° to the southeast. Shear-sense criteria like clast geometries, SCC`-type shear band fabrics as well as abundant microstructures show top to the south/ southsouthwest normal shearing with a dextral strike-slip component. Mineral assemblages in mylonitized granitoid consist of pre- to syntectonic muscovite- and biotite-porphyroclasts as well as dynamically recrystallized potassium feldspar, plagioclase and quartz. Dynamic recrystallization of potassium feldspar and the stability of biotite indicate upper green-schist-facies metamorphic conditions during the early phase of deformation. Fluid infiltration at lower greenschist-facies conditions led to local sericitization of feldspar and synmylonitic chloritisation of biotite during a later stage of ductile deformation. Finally, a brittle overprint by a north-south trending, subvertical, sinistral strike-slip fault that shows a normal component is observed. Ductile normal shearing along the Freyenstein Shear Zone is interpreted to have occurred between 320 Ma and c. 300 Ma. This time interval is indicated by literature data on the emplacement of the hostrock and cooling below c. 300°C inferred from two Rb-Sr biotite ages measured on undeformed granites close to the shear zone yielding 309.6 ± 3 Ma and 290.9 ± 2.9 Ma, respectively. Brittle sinistral strike-slip faulting at less than 300°C presumably took place not earlier than 300 Ma. Early ductile shearing along the Freyenstein Fault System may be genetically, but not kinematically linked to the Strudengau Shear Zone, as both acted in an extensional regime during late Variscan orogenic collapse. A relation to other major northeast-southwest trending faults of this part of the Bohemian Massif (e.g. the Vitis-Pribyslav Fault System) is indicated for the phase of brittle sinistral movement.
The St. Veit Klippen Unit in Vienna (Austria) – Jurassic to Cretaceous biostratigraphy and facies based on historical fossil collections
Authors: Lukeneder Alexander , Lukeneder Petra , Harzhauser Mathias
Published: January 2021

Historical fossil assemblages from the Lower Jurassic to Lower Cretaceous of the Sankt Veit Klippen Unit (SVK) on the western outskirts of Vienna were re-evaluated. Collections of the material from the St. Veit Klippen Unit comprise 3497 specimens. An appropriate nomenclature was used, and the taxonomy was partly revised. Historical collections from Franz Toula (1845–1920) and Friedrich Trauth (1883–1967) were investigated in the collections of the Natural History Museum Vienna, the Geological Survey Vienna, the Department of Geology and the Department of Palaeontology (both University Vienna). Additional collections were studied in the district museums Hietzing (13th district Vienna) and Liesing (23rd district Vienna), in the district municipal office of Hietzing and in the Wienerwald Museum (Eichgraben, Lower Austria). The study area is situated in the easternmost part of the St. Veit Klippen Unit in the Wienerwald (Vienna Woods), part of the 13th Viennese district Hietzing. New data allowed a revision of the biostratigraphy of several lithological units of the SVK. Two main fossil complexes could be distinguished: 1) the Hohenauer Wiese assemblage from the wildlife park Lainz (= “Lainzer Tiergarten”) and 2) the Glasauer quarry assemblage from St. Veit.
A Comparative Analysis of Conceptual Bases of Modern Educational Systems and Educational Practices (on the Example of Comparison of the System of Developmental Instruction and Reflective-Activity Approach)
Authors: Zaretsky V.K. , Zaretsky Y.V. , Ostroverkh O.S. , Tikhomirova A.V. , Fedorenko E.Y.
Published: January 2021

The article is written in the framework of the research project of the Moscow state university of psychology and education "Development of a conceptual model of a new school". In this article, the authors attempt to start a comparative analysis of conceptual educational systems and practices that have common value and theoretical and methodological foundations and can become the basis for building the educational process within the framework of the project being developed. It is important to enrich understanding of how the principles of subjectness, cooperation, and development can be implemented on a school-wide scale through a comparison of the system of developmental instruction training and the reflexive-activity approach. The article attempts to integrate these approaches in the process of designing a new school.
Constituição Júlia: uma carta-mulher de trinta
Authors: Assis Ana Elisa Spaolonzi Queiroz , Figueiredo Eduardo Henrique Lopes
Published: January 2021

Resumo: Considerando a fecundidade simbólica entre a escrita literária como percepção da política enquanto hipótese, o presente texto buscar tecer relações entre o desenrolar destes pouco mais de trinta anos da constituição brasileira e a vida de Julia, protagonista da obra "A mulher de trinta anos". Por meio de abordagem qualitativa de pesquisa documental, traçamos a discussão dividindo-a em décadas associadas aos três primeiros capítulos da obra em comento, de forma a estabelecer o momento da proposta de consolidação da constituição, passando por uma tentativa de efetivações mais contundentes de direitos e finalizando com uma conjuntura de autoconhecimento jurídico-normativo. Como resultados, deixamos provocações para consolidação de um tempo de reconhecimento das capacidades irresistíveis da Carta Balzaquiana, sem perder de vista o fato de que, para que a Constituição exista, é necessário a incrementação da dimensão relacional dos direitos.Palavras-chave: constitucionalismo, história do direito, literatura, políticas públicas.Abstract: Considering the symbolic fecundity between literary writing as a perception of politics as a hypothesis, this text seeks to weave relations between the development of these thirty years of the Brazilian constitution and the life of Julia, protagonist of the work "A woman of thirty". Through a qualitative approach to documental research, we traced the discussion by dividing it into decades associated with the first three chapters of the work in question, in order to establish the moment of the proposal for consolidation of the constitution, going through an attempt of more forceful realization of rights and ending with a conjuncture of legal-normative self-knowledge. As a result, we left provocations to consolidate a period of recognition of the irresistible capabilities of the Balzaquian Charter, without losing sight of the fact that, for the Constitution to exist, it is necessary to increase the relational dimension of rights.Keywords: constitutionalism, history of law, literature, public policy.
Invasive potential of retroperitoneal well-differentiated liposarcomas depending on the extent of sclerosing component in the tumor
Authors: Volkov A. Yu. , Kozlov N. A. , Nered S. N. , Stilidi I. S. , Stroganova A. M. , Archery P. P. , Antonov E. Yu. , Privezentsev S. A.
Published: January 2021

Objective. To assess the influence of the extent of sclerosing component in the retroperitoneal well-differentiated liposarcoma (WDLPS) on the survival.
Material and methods. The retrospective study included 111 patients with primary retroperitoneal WLPS who underwent radical surgical treatment in Federal State Budgetary Institution N.N. Blokhin National Medical Research Center of Oncology. Histological slides of all surgical specimens were reviewed by experienced pathologist and reclassified according to criteria of WHO (2013). Patients were divided into groups depending on the extent of the sclerosing component in the tumor and enrolled in intergroup analysis. We analyzed relationship between extent of the sclerosing component in the tumor and frequency of the pathologically confirmed visceral invasion. Also, we have analyzed the influence of the visceral invasion of WDLPS on the long-term results overall (OS) and recurrence-free (RFS) survival.
Results. Pathologically confirmed visceral invasion was revealed in 17% of cases with the sclerosing component less 20%, and in 31% of cases with the sclerosing component more 20%. OS was significantly worse in the group of patients who suffered from WDLPS with visceral invasion than in the group of patients without visceral invasion (p = 0.009; logarithmic criterion). The median OS in the compared groups was 85 (95% CI, 84, 87) and 142 (95% CI, 109, 175) months, the 5-year OS rate was 41% and 86%, respectively. RFS was significantly worse in the group of patients with histologically confirmed visceral invasion than in the group without organ invasion (p = 0.001; logarithmic criterion). Median RFS in the compared groups was 26 (95% CI, 20, 32) and 57 (95% CI, 38, 76) months, 2-year RFS 33% and 85%, respectively.
Conclusion. Results of the study demonstrate more aggressive behavior of WDLPS with increasing extent of the sclerosing component. We believe that semi-quantitative counting of sclerosing component in retroperitoneal WDLPS can serve as an effective morphological marker of a less favorable prognosis of the disease.
Association of gene expression with lymph node breast cancer metastasis
Authors: Grishina K. A. , Kipkeeva F. M. , Pospekhova N. I. , Khaylenko V. A. , Karpukhin A. V.
Published: January 2021

The most serious complication of breast cancer (BC), which affects life expectancy, is metastasis of the tumor. Metastasis is the cause of more than 80% of all breast cancer deaths. After surgical treatment and the use of adjuvant therapy, metastases occur in 8% 15% of cases. This indicates the need to develop markers for the prognosis of metastasis and clarify its mechanisms for the creation of anti-metastatic therapeutic agents. In this paper, we studied the association of LOX and uPAR gene expression with breast cancer metastasis in the lymph nodes.
Gene expression was measured using real-time PCR in 40 paired samples (tumor-normal tissues). As a result of processing the measurements, the values of gene expression levels in the tumor tissue relative to normal were obtained.
It is shown that the LOX gene is expressed in the tumor both lower and higher relative to the norm, and uPAR is expressed in most cases higher. In metastatic tumors, the frequency of expression increases above the norm for both LOX and uPAR genes. The association of expression of these genes with lymphatic metastasis was found: p = 0.01 and p = 0.02, for the LOX and uPAR genes, respectively. The relative risk (RR) was for the LOX gene RR = 1.9, 95% CI 1.2 3, p = 0.005, for uPAR RR = 3.6, 95% CI 1.2 10.9, p = 0.03.
Thus, the data obtained contribute to understanding the mechanisms of metastasis and provide the basis for the development of new biomarkers. The LOX and uPAR genes may be candidates for predictive markers of breast cancer metastasis risk.
Prevention of mother-to-child HIV transmission: from the first stages to the possibility of elimination
Authors: Mozalyova Olga L. , Samarina Anna V.
Published: January 2021

Despite the success in reducing mother-to-child HIV transmission rate worldwide, the problem of perinatal HIV transmission is still relevant. Sexual activity nowadays is the predominant way of transmission, therefore the number of HIV cases among women growths. This leads to an increased number of pregnancies and childbirth in HIV-infected women. Better preventive treatment has decreased the transmission risk to 1% or less. Despite this, the Russian Federation is still not among the countries where the elimination of mother-to-child transmission has been recorded. This review article focuses on the main stages of mother-to-child transmission prevention from the time that no antiretroviral therapy was available to the current stage, when highly active antiretroviral therapy is used during pregnancy, childbirth and for the treatment of newborns. The research provides a comparative analysis of modern national and international clinical recommendations for the prevention of mother-to-child HIV transmission.
Case reports of patients with chronic disorders of consciousness in obstetric and gynecological practice
Authors: Ivanova Alina O. , Kondratyeva Ekaterina A. , Yarmolinskaya Maria I. , Misharina Elena V. , Florova Margarita S. , Kondratyev Anatoly N.
Published: January 2021

According to the modern classification system, chronic disorders of consciousness are defined as an altered state of consciousness that develops after coma and is accompanied by the restoration of wakefulness without the complete recovery of conscious activity for more than 28 days after traumatic brain injury. Clinical cases of chronic chronic disorders of consciousness development in women after surgical interventions related to various obstetrical and gynecological pathologies, as well as after routine surgical interventions for comorbid somatic pathology, are of particular interest to obstetricians and gynecologists. In the presented chronic chronic disorders of consciousness related clinical cases of operations for ectopic pregnancy, as well as consequences of elective surgery for gallstone disease, the development of hypo- and normogonadotropic ovarian insufficiency associated with chronic disorders of consciousness is described. The characteristics of the thyroid status, adrenocorticotropic function, and vitamin D levels are given. Further in-depth examination and accumulation of data on patients with chronic disorders of consciousness may provide an opportunity to determine informative markers for prognostication of outcomes, as well as to develop new effective approaches to consciousness rehabilitation in this category of patients.
Morphological features of the placenta in obese women
Authors: Seryogina Darya S. , Sosnina Alexandra K. , Tral Tatyana G. , Tolibova Gulrukhsor Kh. , Mozgovaya Elena V.
Published: January 2021

Hypothesis/Aims of study. Obesity and severe chronic somatic pathology in a woman leads to a rapid depletion of compensatory and adaptive reserves of the placenta and to the progression of circulatory and dystrophic changes, which causes intrauterine growth retardation and reduces the likelihood of a favorable course of pregnancy and childbirth. The aim of this study was to assess the morphological features of the vascular component of placental villi in obese women.
Study design, materials and methods. Histological and immunohistochemical studies were conducted on 41 placentas from obese patients with and without gestational diabetes mellitus and from healthy patients, endothelial marker CD34+ expression being assessed in chorionic villi.
Results. In obese patients, chronic placental insufficiency is presented in most cases as a dissociated form with persistence of not only mature but also immature villi, which indicates early structural pathology of the placenta.
Conclusion. Obesity in women contributes to more frequent chronic placental insufficiency with severe circulatory disorders and varying degrees of severity of compensatory and adaptive changes.
Stigmatization as a psychological resource for rehabilitation of cardiology clinic patients
Authors: Solovyova Svetlana L. , Vlasova Natalya V.
Published: January 2021

Aim. Identify the adaptive level of stigma and describe its characteristics.

Methods. Adapted for the cardiology clinic questionnaire of N. Sartorius, symptomatic questionnaire SCL-90-R (Simptom Check List-90-Revised), Schutzs Interpersonal relations questionnaire (1958), Tobol test method of the type of attitude to disease and treatment, and the Personal differential questionnaire. The data obtained were processed using the statistical program SPPS 20.

Results. The study determined the optimal degree of stigmatization, which performed a positive role in relation to the state of health, helping patients to adequately assess the severity of the pathology, identify themselves with the disease and realize the necessary measure of their own responsibility in the treatment process (from 48 to 60). Clinical and social factors of optimal degree of stigmatization and successful rehabilitation of cardiology clinic patients are identified (resources): the patients higher education and the familys tendency to low-protecting position potentially contribute to the treatment and rehabilitation of cardiology clinic patients with moderate severity of their somatic condition. Clinical and social factors (anti-resources) that prevent the formation of an optimal degree of stigmatization and successful rehabilitation of patients are identified: the operative type of treatment, the overprotective position of the family, which is not justified by a real need, and the low level of education. It is established that the absence of pronounced pathocharacterological features and difficulties in interpersonal interaction of patients with an average level of stigmatization is an argument for determining this level of stigmatization as a resource. According to the results of the study the tasks for the medical psychologist of the cardiology clinic are set:

1) diagnostic, which consists in determining the level of stigmatization, analyzing the ratio of the degree of stigmatization and the degree of severity of cardiovascular pathology, studying individual resources and anti-resources (attitude to the disease and treatment, pathocharacterological features and interpersonal features);

2) psychocorrective, which consists in forming an adequate position in relation to the disease and treatment of patients and their families, restoring intra-family ties, changing inadequate responses to the disease, creating realistic attitudes to treatment in patients and their family members.

Conclusion. The average degree of stigmatization is formed in patients in the absence of a pronounced personal and interpersonal problems, allowing them to receive social support in the conditions of restrictions imposed by the disease, and adapt to it. The average level of stigmatization in this case acts as an additional psychological resource for patients.
Schizophrenia as a subject of competence of psychiatrist, narcologist, cardiologist, endocrinologist and pathologist
Authors: Sivolap Yury P. , Portnova Anna A. , Yanushkevich Maxim V. , Savchenkov Vladimir A. , Pushin Pavel V.
Published: January 2021

Numerous studies show that people with schizophrenia live 1025 years less than the general population. The significant reduction in life expectancy is due to suicides, frequent comorbidity with heart and vascular diseases, metabolic disorders, including obesity and type 2 diabetes, as well as side effects of second-generation antipsychotics. Conditions for reducing the number of premature deaths in schizophrenia include changing the lifestyle of patients with improved nutrition and increased physical activity, increasing patient adherence to antipsychotic therapy with monitoring of the side effects of second-generation antipsychotics, as well as to the treatment of comorbid substance use disorders and comorbid somatic diseases.
Dampak Non-Debt Tax Shield dan Resiko Bisnis Terhadap Struktur Modal Perusahaan Manufaktur Indonesia
Authors: Suryani Ani Wilujeng , Sari Mitha Icha
Published: January 2021

Capital structure decision is an important act made by company’s financial manager as mismanagement causes financial distress. This study aims to determine the effect of non-debt tax shield and business risk on capital structure. The data in this study were collected from the financial reports of 137 manufacturing companies in Indonesia from 2014 to 2019. Hypothesis testing was carried out using a fixed effect panel regression model. The results showed that the non-debt tax shield had a significant negative effect on capital structure, while business risk had a positive effect. Thus, companies that have a low non-debt tax shield will increase their debt to get compensation for tax deductions from interest expenses, while companies with a high risk level prefer internal financing to decrease the debt level. This study contributes to the literature by uncovering the factors that influence the determination of corporate debt levels in manufacturing industries in Indonesia. The result of this research can be used by the company managers to consider business risk and non-debt tax shields in determining the optimum capital structure to increase the value of the company.
Arranged Marriage, Partner Traits and Parental Investment
Authors: Hasnain Annemarie M.
Published: January 2021

Both sexes choose mates based on qualities that will enhance offspring viability and quality.
In some cases individuals are forced to reproduce with less desirable mates which has been shown
to result in lower quality offspring. The Reproductive Compensation Hypothesis (RCH) predicts that
parents who mate under constraint will increase their reproductive effort and investment in offspring
to compensate for lowered offspring viability. Evidence for the RCH has been found in several animal
species; however it has not been examined in humans. One possible type of mate choice constraint in
humans is that of arranged marriage in which parents or others choose mates for individuals. In order
to test the RCH, I examine whether there are differences in both partner traits between women in
arranged marriages and those in self-choice marriages, and differences in parental investment between
women in arranged and self-choice marriages using data from the Indonesian Family Life Survey. Except
for husband’s education level, no differences were found in mate characteristics between the husbands
of women in self-choice marriages and those in arranged marriages. Marriage type did not significantly
correlate with parental investment except for number of live births. This correlation, however, was not
in the predicated direction. Results show that women in self-choice marriages had more offspring
(controlling for marriage duration) than woman in arranged marriages. It is possible that arranged
marriage is not a true constraint on mate choice or that parental investment measures used in this
study need to be more refined.