bluuebunny/crossref_metadata_2025 huggingface dataset:
Multiprofessional approach for class III malocclusion rehabilitation with autogenous calvarial bone graft followed by Le Fort 1 osteotomy and implant-supported prostheses – case report
Authors: Borella Paulo Sérgio , Alves Júlio César de Carvalho , Alvares Larissa Ayres Scagliarini , Souza Áquila Valente de , Mota Karoline Ferreira da , Costa Sérgio Antônio Araújo , Zancopé Karla , Prudente Marcel Santana , Neves Flávio Domingues das
Published: June 2021

Extensive treatments can eventually be challenging. Even more so when the patient has limitations such as extensive tooth loss and skeletal changes, including overgrowth of the lower jaw. When indicated, these treatments tend to discourage patients due to the history of previous failures. Therefore, in addition to an interdisciplinary dental team composed of oral and maxillofacial surgeons, and prosthodontists, a nutrologist, a speech therapist, and a psychotherapist were involved in the treatment of this case. A 52-year-old female patient, Angle Class III malocclusion, with few teeth and extensive maxillary bone loss, attended the dental clinic of the Brazilian Association of Dentistry in Uberlândia. The treatment involved reverse planning, extraction of the dental remnants, calvarial bone grafting, placement of 6 titanium implants (Neodent) in the maxilla (upper jaw) and 5 in the mandible (lower jaw), orthognathic surgery, and installation of implant-supported fixed complete dentures in both jaws. Furthermore, psychotherapeutic and nutrologist’s interventions were necessary during the dental treatment, concluding the treatment with speech therapy. Within the limitations of this case, the multidisciplinary approach proved to be efficient. It promoted the reestablishment of the stomatognathic system functions without compromising nutrition during the periods when it was impossible to wear prostheses for better healing of the tissues.
Uso de resina pré-aquecida como material cimentante em restauração indireta: Uma revisão de literatura
Authors: Teixeira João Pedro Silva , Cavalcante Samara Kelly da Silva , Roncolato Álvaro Tavares Lins , Mendes Talita Arrais Daniel , Pinto Ana Carolina Matias Dinelly , Brito Raynara de Sousa , Fontes Natasha Muniz , Silva Raul Anderson Domingues Alves da , Isaias Pedro Henrique Chaves , Dinelly Érika Matias Pinto
Published: June 2021

Devido ao grande apelo estético com o decorrer dos anos associado há técnicas minimamente invasivas, a odontologia contemporânea aposta em materiais com ótimas características estéticas e mecânicas, dessa forma os cirurgiões dentistas buscam apostar no uso do pré-aquecimento das resinas compostas como material cimentante para restaurações indiretas, visto que suas propriedades ópticas e mecânicas propõem uma melhor estética e uma melhor adaptação marginal em comparação aos cimentos resinosos. O objetivo deste trabalho é revisar a literatura a cerca das características ópticas e mecânicas dos diferentes materiais utilizados como agente cimentantes em restaurações indiretas, enfatizando a estabilidade de cor ao longo prazo, adaptação marginal, toxicidade, grau de conversão dos monômeros e praticidade clínica. Para tanto, foi realizada uma busca eletrônica na base de dados Sistema Online de Busca e Análise de Literatura Médica (PubMed), utilizando os seguintes descritores em inglês: thermoactivated resin, temperature e dental veneers, cadastrados no Mesh (Medical Subject Headings) combinado entre si pelo operador boleano “AND”. Após a delimitação de 10 anos para a busca, foram encontrados 50 artigos. Destes, foram selecionados 13 estudos, com base na leitura de títulos e resumos. Em suma, as resinas pré-aquecidas apresentam ótimas características mecânicas e ópticas, no entanto cabe ao cirurgião-dentista escolher qual técnica é mais viável em sua pratica clínica.
Aplicativo mentalpro para auxílio na suspeição de transtornos mentais na Atenção Básica em Saúde
Authors: Silva Jorge Luiz Lima da , Meirelles Igor Barreto , Ramos Gabriella Filippini Silva , Abreu Larissa Murta , Martins Alexander Rivail Ruiz
Published: June 2021

Objetivo: relatar a experiência da construção de aplicativo para auxílio da suspeição de transtornos mentais comuns, para usuários da rede básica de saúde. Metodologia: trata-se de relato de experiência do passo a passo da construção de protótipo tecnológico que objetiva a construção de aplicação híbrida, desktop e mobile, com base em escalas validadas no Brasil. Resultados: o design do aplicativo foi elaborado de forma que as etapas de coleta de informações e respostas dos questionários fossem parecidas com um chat em tempo real. As correções e adequações finais, foram realizadas mediante testagens de funcionamento e demandas que surgiram durante a elaboração, até a apresentação da versão final. Conclusão: percebe-se que o aplicativo "MentalPro" poderá ser uma ferramenta útil, em ambientes como salas de espera, pré-atendimento, consultas de enfermagem ou médicas, e triagem, auxiliando os profissionais e direcionando os cuidados adequados para promoção da saúde mental. O produto é de livre acesso e se propõe a adaptações necessárias com uso junto à comunidade.
Ensino remoto sobre processo de enfermagem na pandemia da Covid-19: Relato de experiência
Authors: Camacho Alessandra Conceição Leite Funchal , Souza Vitória Meireles Felipe de , Menezes Harlon França de
Published: June 2021

Objetivo: descrever as estratégias de planejamento e o desenvolvimento do ensino remoto sobre o processo de enfermagem na Pandemia da COVID-19. Metodologia: trata-se de um relato de experiência acerca das estratégias de ensino remoto empreendidas na disciplina de Fundamentos de Enfermagem III sobre o Processo de Enfermagem com período de coleta de dados de Julho a Novembro de 2020. A análise realizada foi do tipo descritiva. Resultados: A interatividade no ensino remoto foi fundamental para o planejamento contínuo do ambiente virtual por meio do uso de ferramentas e aplicativos frente ao isolamento social imposto pela Pandemia. Conclusão: a possibilidade de buscar a interatividade na educação remoto nos seguintes aspectos: planejamento contínuo; o docente como aquele que faz a mediação do conhecimento; combinação do ambiente virtual de aprendizagem com as necessidades atuais do ensino remoto.
Comportamento de nidificação de Melipona scutellaris (Latreille, 1811)
Authors: Silva Flávia Janaína de Araújo , Aquino Italo de Souza , Barbosa Alex da Silva , Borges Péricles de Farias
Published: June 2021

A ambiência é um dos fatores relevantes na criação racional de abelhas. A abelha uruçu (Melipona scutellaris) é uma espécie nativa do Brasil, conhecida por sua grande produção de mel em relação aos demais meliponíneos e fácil manejo. A enxameação, porém, pode desestabilizar a produção de mel. O objetivo dessa pesquisa foi estudar o comportamento de nidificação da abelha M. scutellaris em colmeias octogonais expostas aos fatores abióticos do ambiente. O experimento foi desenvolvido em dois municípios (Lagoa Seca e Areia) localizados na microrregião do brejo paraibano. Utilizou-se 20 colmeias octogonais, com 8 orifícios cada, representando os pontos cardeais (N, S, L, O) e colaterais (NE, SE, SO e NO). Avaliou-se a influência do horário de nidificação, evolução do fechamento dos orifícios, efeito da direção e velocidade do vento, e influência da temperatura e umidade relativa do ar na abertura e fechamento dos orifícios de nidificação. Conclui-se que 1. A atividade de fechamento dos orifícios da colmeia octogonal com M. scutellaris acontece com mais frequência no período da tarde (das 12 às 16 horas); 2. Em Lagoa Seca-PB, as abelhas M. scutellaris apresentam preferência de nidificação na orientação colateral NE, evitando a orientação O; 3. Em Areia-PB, as abelhas M. scutellaris preferem a orientação cardeal N como ponto de nidificação e evitam a orientação SE; 4. O aumento da temperatura e da umidade relativa do ar aumentam a abertura dos orifícios em colmeias octogonais ocupadas por M. scutellaris; e 5. O aumento na incidência e velocidade do vento reduzem a possibilidade da existência de orifícios abertos em colmeias octogonais povoadas com M. scutellaris.
Protagonismo da enfermagem na vacinação e avaliação da cobertura vacinal contra o Papiloma vírus humano em municípios da 18ª Regional de Saúde do Paraná
Authors: Imamura Simone , Fagundes Tatiane Renata
Published: June 2021

O câncer de colo de útero é a quarta maior causa de mortalidade entre mulheres, e está diretamente relacionada com a infecção pelo HPV. As linhagens oncogênicas desse vírus possuem tropismo pela região pélvica e podem ser transmitidas durante a relação sexual, se tornando importante no cenário epidemiológico da população jovem. Diante da importância de medidas que objetivem a prevenção do carcinoma cervical, o objetivo do presente trabalho foi realizar um levantamento bibliográfico de abordagem qualitativa, exploratória e do­cumental acerca da vacinação contra o HPV e o papel do profissional da enfermagem nesse contexto. Para tal, realizou-se uma pesquisa nas bases de dados Scielo, Periódicos Capes e Biblioteca Vir­tual de Saúde, com os descritores Papillomavirus Humano e vacinas. Observou-se que os índices de vacinação diminuíram desde que a vacina contra HPV foi instituída no PNI em 2014. O Paraná apresentou índice de vacinação semelhante ao nacional em 2014 e 2015, com um leve aumento em 2016. A baixa adesão à vacinação é multifatorial, estando diretamente relacionada com a condição socioeconômica e à quantidade de informação a que essa população tem acesso. Com isso o profissional da enfermagem se torna parte primordial em todo o contexto epidemiológico do carcinoma cervical. Cabe a esse profissional não só a aplicação correta de técnicas de enfermagem na aplicação da vacina, quanto o acompanhamento individual de cada paciente. Permitindo assim a correção de dogmas e informações erradas e levando conhecimento a toda a comunidade.
Determinantes da satisfação com o serviço de água e saneamento: A opinião das partes interessadas na Pacasmayo
Authors: Baltodano Contreras Wilman Erik , Rojas Luján Víctor William
Published: June 2021

El propósito de este trabajo fue analizar los factores críticos de éxito determinantes de la satisfacción (FCEDS) de acuerdo a la opinión de los stakeholders vinculados a la gestión del servicio de agua y saneamiento en la Municipalidad de Pacasmayo en Perú. Se realizó un muestreo no probabilístico intencionado, de 55 stakeholders comunitarios en los 11 sectores céntricos y a 25 funcionarios. Se empleó un cuestionario basado en la Best – Worst Scaling (BWS) que consideró 16 indicadores y que considera cuatro dimensiones: Aspectos Técnicos del Servicio, Aspectos de Calidad del Servicio, Aspectos Económicos y Financieros y Aspectos Legales y entorno político. La fiabilidad se hizo con el Coeficiente Kuder-Richardson (KR-20= 0.841). Se calcularon las puntuaciones y se compararon las percepciones de ambos grupos (Prueba U de Mann-Whitney). La exploración de los FCEDS en los stakeholders comunitarios y funcionarios, resalta la importancia de los aspectos de calidad del servicio y aspectos técnicos, otorgando menor interés a los aspectos legales y entorno político, así como los aspectos económicos y financieros. La comparación de las percepciones de ambos grupos de estudio no arrojó diferencias significativas (p-valor > 0.05). Se recomienda mejorar los niveles de corresponsabilidad de los stakeholders que participan en la gestión del servicio de agua y saneamiento en Pacasmayo y atender a las necesidades que se desprenden de la identificación de los FCEDS.
Analisando os objetivos de desenvolvimento sustentável (ODS) na gastronomia do Sertão Paraibano
Authors: Silva Isabel Christina Araújo da , Maracajá Kettrin Farias Bem
Published: June 2021

A gastronomia tem crescido como um atrativo dentro da experiência turística do visitante e parte integrante da cultura local. Desse modo, repensando as atividades turísticas gastronômicas de modo mais sustentável, à luz da Agenda 2030 e seus 17 Objetivos de Desenvolvimento Sustentável, e alinhando tais temáticas, o presente estudo buscou analisar de que forma o queijo artesanal de leite de cabra, produzido na Fazenda Carnaúba de Taperoá - Paraíba, pode contribuir na promoção da cultura e na geração de emprego, relacionando-o com os ODS. Quanto à metodologia, trata-se de uma pesquisa exploratória com relação aos seus objetivos; no que diz respeito aos procedimentos técnicos, a pesquisa conta com um estudo de caso, na Fazenda Carnaúba, com a aplicação de questionários aos consumidores do queijo, bem como o produtor/proprietário. No que tange a questão de pesquisa, considera-se um estudo exploratório, bibliográfico e documental. Sendo considerada uma pesquisa qualitativa, com o viés quantitativo ao interligar os objetivos do estudo e os respectivos ODS através de uma mensuração gráfica das respostas obtidas nos questionários, contando com o auxílio do software RStudio para geração desse material gráfico. Dessarte, percebeu-se que o queijo artesanal contribui como um promotor da cultura local e gerador de emprego e renda; identificou-se também que o produto colabora diretamente com o desenvolvimento de metas e objetivos contidos nos ODS da Agenda 2030.
Resíduos orgânicos e biocarvões para fins de condicionante de solos
Authors: Souza Janardelly Gomes de , Santos Bruna Caroline Silva dos , Costa Maria Eduarda da Silva , Santos Marlon Kipson dos , Santos Carlos Henrique dos , Mazzuchelli Rita de Cássia Lima , Alves Marcelo Rodrigo
Published: June 2021

O objetivo do presente estudo foi caracterizar matérias-primas e biocarvões produzidos em condições de laboratório, além de fornecer informações referentes a viabilidade de uso do biocarvão no solo. Assim, numa primeira etapa o biocarvão foi produzido a partir da amostra seca de biossólido (BP) e de bagaço de cana-de-açúcar (BCP), por meio da pirólise lenta a temperatura de 350°C por 30 minutos. Numa segunda etapa foi realizado a caracterização das matérias-primas e seus respectivos biocarvões. Foi utilizado um delineamento com cinco repetições, sendo que os tratamentos foram constituídos por: biossólido puro; bagaço de cana-de-açúcar puro; biocarvão de biossólido (BB); biocarvão do bagaço de cana-de-açúcar (BBC). Onde a avaliação dos resíduos foi por meio das análises de: rendimento de massas, imediatas, potencial hidrogeniônico, capacidade de troca catiônica, teor de nutrientes, espectrometria de fluorescência de raio x, bromatológica, densidade e tamanho de partículas. Os dados obtidos foram submetidos à análise de variância (ANOVA) pelo programa SISVAR. Para comparação de médias, foi utilizado o teste de Tukey a 5% de probabilidade (p<0,05). Conclui-se que tanto as matérias-primas quanto os biocarvões, produzidos por pirólise lenta a 350ºC, apresentaram características propícias para o uso agrícola, principalmente em termos de fertilidade.
Efeitos da fotobiomodulação e exercícios na dor e força muscular na osteoartrose de joelho: Uma revisão sistemática
Authors: Ferreira Elaine dos Santos , Santos Erica Tainara Alves dos , Leal Seânia Santos
Published: June 2021

Introdução: A osteoartose consiste em uma doença degenerativa que pode ou não estar associada a processos inflamatórios, um dos recursos terapêuticos possíveis para o tratamento dessa enfermidade é a fotobiomodulação laser. Objetivos: Este estudo tem como objetivo, analisar por meio de uma revisão sistemática de literatura, a eficácia da fotobiomodulação e exercícios na da dor e força muscular na osteoartrose de joelho. Metodologia: Foi realizado um levantamento bibliográfico nas bases de dados Medline, PubMed e Scielo, utilizando como descritores: osteoartrose, fotobiomodulação, fisioterapia, terapia a laser. Foram identificados 35 artigos com ano de publicação entre 2011-2020, escritos nos idiomas português e inglês. Posteriormente, foram lidos os resumos dos artigos, eliminando-se 29 artigos que não atenderam aos critérios. Resultados: 6 artigos compuseram essa revisão, demonstraram diferentes parâmetros de laser infravermelho, e diferentes protocolos de exercícios, porém todos com bons resultados. Conclusão: conclui-se que o uso da fotobiomodulação do laser infravermelho associado ao treino de força tem grande eficácia no tratamento de pacientes com osteoartrose de joelho.
Japanese amberjack Seriola quinqueradiata and red sea bream Pagrus major susceptibility to infectious hematopoietic necrosis virus (IHNV) isolate
Authors: Ito T , Kamaishi T
Published: June 2021

Infectious hematopoietic necrosis virus (IHNV) is known as a causative agent of heavy mortalities in farmed rainbow trout. However, there is limited information on its virulence for marine fish species. In this study, Japanese amberjack Seriola quinqueradiata and red sea bream Pagrus major were experimentally infected by intraperitoneal (IP) injection and immersion, with an IHNV isolate from rainbow trout in Japan, to evaluate the virulence of the virus for these fish species. The cumulative mortality for immersed rainbow trout was 15%. IHNV was isolated from all dead fish and 50% of the sequentially sampled rainbow trout. When Japanese amberjack were challenged by IP injection and immersion, the resulting cumulative mortality was 70% and 0%, respectively. The virus was isolated from all dead fish and 1 out of 3 Japanese amberjack sampled at 9 d post exposure. However, no mortality was observed in either of the red sea bream groups challenged with IHNV. IHNV was not isolated from any of the surviving red sea bream, or from any of the sequentially sampled fish. The viral titer on Japanese amberjack-derived YTF cells was in the same log range as that on FHM and RTH-149 cells, but the titers on the red sea bream cell lines SBK and GBRS were lower than the other cell lines, and were significantly different from the FHM and RTH-149 cell lines. These results suggest that Japanese amberjack has a low susceptibility to IHNV, and red sea bream has no or little susceptibility to the virus.
Effect of light on the trematode Himasthla elongata: from cercarial behaviour to infection success
Authors: Correia S , Freitas R , de Montaudouin X , Magalhães L
Published: June 2021

The cockle Cerastoderma edule, a socioeconomically important bivalve of the northeast Atlantic, is host to several trematodes, including Himasthla elongata. In the life cycle of this trematode, cercariae (free-living stages) emerge from the first intermediate host, a snail, to infect cockles as second intermediate hosts. During their lifespan (less than 2 d), cercariae must ensure successful host-to-host transmission via the surrounding water and therefore are exposed to and impacted by different environmental conditions, including abiotic factors. Given that the light:dark cycle is one of the major drivers of behaviour in aquatic habitats, we aimed to determine the influence of light on cercariae and host behaviour based on 3 hypotheses. First, by having a benthic second intermediate host, these cercariae will display a photonegative orientation; second, and conversely, host behaviour will not be influenced by light; and third, cercariae infection success will be light-dependent. Results showed that cercariae display a photopositive orientation (first hypothesis rejected), displaying movements towards light. Host activity (evaluated by oxygen consumption) was similar among conditions, i.e. dark vs. light (second hypothesis accepted), but hosts acquired more parasites when experimentally infected in the dark (third hypothesis accepted). This light-dependent infection of the host is explained by a change of cercarial behaviour when exposed to light, decreasing their infection success. This study highlights that trematode responses to external conditions may be linked to successful life cycle completion rather than being altered by the host habitat. Light influence on cercarial behaviour resulted in increased infection success that may affect trematode population dynamics and their distributional range.
The effect of antioxidant treatment and NOS inhibition on the incidence of ischaemia-induced arrhythmias in the diabetic rat heart
Authors: Matejíková J , Kucharská J , Pancza D , Ravingerová T
Published: June 2021

Contrary to clinical trials, experimental studies revealed that diabetes mellitus (DM) may initiate, besides increased myocardial vulnerability to ischemia-reperfusion injury (I/R) and pro/antioxidant dysbalance, development of adaptation leading to an enhanced tolerance to I/R. The aims were to characterize 1) susceptibility to ischemia-induced ventricular arrhythmias in the diabetic rat heart 2) its response to antioxidant N-acetylcysteine (NAC) and a NOS inhibitor L-NAME, and 3) the effect of DM on endogenous antioxidant systems. Seven days after streptozotocin injection (65 mg/kg, i.p.), Langendorff-perfused control (C) and DM hearts were subjected to 30-min occlusion of the LAD coronary artery with or without prior 15-min treatment with L-NAME (100 microM) or NAC (4 mM). Total number of ventricular premature beats (VPB), as well the total duration of ventricular tachycardia (VT) were reduced in the DM group (from 533+/-58 and 37.9+/-10.2 s to 224.3+/-52.6 and 19+/-13.5 s; P<0.05). In contrast to the antiarrhythmic effects of L-NAME and NAC in controls group (VPB 290+/-56 and 74+/-36, respectively; P<0.01 vs. control hearts), application of both drugs in the diabetics did not modify arrhythmogenesis (L-NAME: VPB 345+/-136, VT 25+/-13 s; NAC: VPB 207+/-50, VT 12+/-3.9 s; P>0.05 vs non-treated diabetic hearts). Diabetic state was associated with significantly elevated levels of CoQ10 and CoQ9 (19.6+/-0.8 and 217.3+/-9.5 vs. 17.4+/- 0.5 and 185.0+/-5.0 nmol/g, respectively, in controls; P<0.05), as well as alpha-tocopherol (38.6+/-0.7 vs. 31.5+/-2.1 nmol/g in controls; P<0.01) in the myocardial tissue. It is concluded that early period of DM is associated with enhanced resistance to ischemia-induced arrhythmias. Diabetes mellitus might induce adaptive processes in the myocardium leading to lower susceptibility to antioxidant and L-NAME treatment.
Lack of the effect of superoxide dismutase and catalase on Na+,K+-ATPase activity in stunned rabbit hearts
Authors: Kaplán P , Matejovičová M , Herijgers P , Flameng W
Published: June 2021

Reactive oxygen species (ROS) have been implicated in the mechanism of postischemic contractile dysfunction, known as myocardial stunning. In this study, we examined protective effects of antioxidant enzymes, superoxide dismutase (SOD) and catalase, against ischemia/reperfusion-induced cardiac dysfunction and inhibition of Na+,K+-ATPase activity. Isolated Langendorff-perfused rabbit hearts were subjected to 15 min of global normothermic ischemia followed by 10 min reperfusion. The hearts treated with SOD plus catalase did not show significant recovery of left ventricular (LV) end-diastolic pressure compared with untreated ischemic reperfused hearts. Treatment with antioxidants had no protective effects on developed LV pressure or its maximal positive and negative first derivatives (+/-LVdP/dt). Myocardial stunning was accompanied by significant loss in sarcolemmal Na+,K+-ATPase activity and thiol group content. Inhibition of enzyme activity and oxidation of SH groups were not prevented by antioxidant enzymes. These results suggest that administration of SOD and catalase in perfusate do not protect significantly against cardiac dysfunction in stunned rabbit myocardium.
Endogenous Protective Mechanisms in Remodeling of Rat Heart Mitochondrial Membranes in the Acute Phase of Streptozotocin-Induced Diabetes
Authors: Ferko M , Habodászová D , Waczulíková I , Mujkošová J , Kucharská J , Šikurová Ľ , Ziegelhoffer B , Styk J , Ziegelhoffer A
Published: June 2021

The aim of present study was to investigate functional and physical alterations in membranes of heart mitochondria that are associated with remodeling of these organelles in acute phase of streptozotocin-induced diabetes and to elucidate the role of these changes in adaptation of the heart to acute streptozotocin-induced diabetes (evaluated 8 days after single dose streptozotocin application to male Wistar rats). Action of free radicals on the respiratory chain of diabetic-heart mitochondria was manifested by 17 % increase (p<0.05) in oxidized form of the coenzyme Q(10) and resulted in a decrease of states S3 and S4 respiration, the respiratory control index, rate of phosphorylation (all p<0.01) and the mitochondrial transmembrane potential (p<0.05), but the ADP/O ratio decreased only moderately (p>0.05). On the contrary, membrane fluidity and the total mitochondrial Mg2+-ATPase activity increased (both p<0.05). In diabetic heart mitochondria, linear regression analysis revealed a reciprocal relationship between the increase in membrane fluidity and decrease in trans-membrane potential (p<0.05, r = 0.67). Changes in membrane fluidity, transmembrane potential, Mg2+-ATPase activity and the almost preserved ADP/O ratio appear as the manifestation of endogenous protective mechanisms participating in the functional remodeling of mitochondria which contributes to adaptation of the heart to diabetes.
The Impacts Of The Great Depression 1929-33 On Hungary’s Economy
Authors: Domonkos Endre
Published: June 2021

The Great Depression of 1929-33 had serious consequences on Hungary’s economy. The Central and Eastern European countries, including Hungary were hit severely by the downturn of the wholesale prices as regards of agricultural products in international markets. Besides declining prices another major problem was that the industrialised countries introduced protectionist measures (customs duties and quotas). As a result of this process, market opportunities were constrained and later ceased to exist. The situation was further aggravated by the fact that the unfavourable gap between agrarian and industrial prices further widened in the 1920s. Although the crisis started to emerge in the agriculture, its effects were extended to the industry as well. Due to the lack of safe markets, heavy industrial branches declined sharply, whereas the volume of output fell modest in the light industry. The bankruptcy of the Austrian Credit Anstalt on 12th Mai 1931 adversely affected Hungary’s financial system. In order to overcome the difficulties, banking holiday was ordered by the government, which coupled with the suspension of all payments and the introduction of foreign exchange control. Foreign trade has changed significantly. In 1937, the share of Hungary’s export in Germany’s trade was 42 percent, which increased to more than 50 percent after the Anschluss. Thus, at the end of the 1930s, the Third Reich became the most important trade partner of Hungary. Thanks to favourable external conditions accompanied by the rearmament programme of Nazi Germany and state intervention, the performance of the Hungarian economy improved, and by 1937 it surpassed the pre-depression level. The Győr Programme, announced on 12th March 1938 with its military and infrastructural development contributed to the economic boom, which had positive impacts both in the heavy and light industrial branches.
Implementation of Omotenashi in Japanese Ryokan
Authors: Wijayanti Wahyu Nur , Saifudin Akhmad
Published: June 2021

Omotenashi, often referred to as Japanese hospitality, is a service to customers based on Japanese spirit and culture. Omotenashi is evident in the services provided by a ryokan, which is a traditional Japanese inn. This paper seeks to describe the application of omotenashi in ryokan management, how omotenashi control is implemented, and what the implementations are. The research was conducted by observing the involvement of the Hyoe Koyokaku ryokan, an old ryokan located in the tourist area of Arima Onsen. From the results of observations and analysis, it was found that ryokan employees control omotenashi as a vision of service to customers through training, instruction, and improvement based on feedback. The implementation of ometenashi is manifested in personalization, host-guest relationships, hospitableness, and lots of little surprises
Community, Social Capital and Festivals. A Pandemic Perspective
Authors: GRADINARU Camelia
Published: June 2021

This paper focuses on the complex relationships among social capital, community development and festivals. The Covid-19 pandemic put a lot of pressure on festivals, forcing an entire industry to adapt and recreate itself. In the restricted sanitary context, the pandemic festivals redefine the sense of events, of community and of social interactions. The empirical data, comprising in-depth interviews with the organisers of the first festival in Romania after lockdown, have revealed the prioritisation of social benefits and the growing connection between festival and community. This study therefore suggests that festivals could be involved more deeply in the community by assuming social charitable causes. Festivals create their own communities of fans but also shape the local communities where they take place.
Critical Factors in Central Government Information and Data Governance - Empirical Study
Authors: WU Chuan-Chun , CHU Hsin-Chung
Published: June 2021

Along with the development of information and communications technology being popular, types of data become rich and multiple, the analysis scope changes from structured data to non-structured data without sorting context, and the data volume becomes huge and is continuously growing. When data application cases and value benefit are gradually noticed in past years, government agencies realize that data could develop the value through cross-boundary collaboration, rather than simple relying on internal processing and analyses, and the collaboration process allows the government cultivating to apply data with added-value and establish evidence-based governance. Aiming at employees in public sectors in the central government of Taiwan, total 320 copies of questionnaire are distributed and 247 valid copies are retrieved, with the retrieval rate 77% . The research results are summarized as below: (1) Regarding the curiosity and expectation of data analysis of the government, either directors of agencies or key case officers, with the expectation of applying the possessed data with added value, do not simply regard data as dead records, but attempt to apply data to solve specific public issues; (2) In addition to inducing the curiosity about data application in the internal organization, success cases of other agencies could facilitate the action of an organization participating in the project for expanding to central and local levels or cross-units inducing the agencies with similar businesses engaging in the project as well as accelerate project influence through experience sharing and reinforce the confidence of other units in information and data governance; (3) Information and data governance could benefit the government shaping positive image to interpret outcomes through data for the reference of future policies, strengthen the industrial and academic research energy of the business, as well as enhance public trust and agency transparency through cooperation with experts. According to the results to propose suggestions, it is expected to provide related policy suggestions for the government examining the internal organization from management to execution about the preparation for data governance and the reference for top decision-makers planning data application strategies, applying data to public-private collaboration, and improving existing data governance structure.
A Study of the Influence of Campus Ecological Environment Integrated Art Education on Learning Attitudes and Effectiveness
Authors: DUAN Shenghua , ZHAO Ruoyi
Published: June 2021

Natural ecology is the basis of social development. The destruction of natural ecological environment would limit the development of society. Environmental issues have become the commonly concerned problems internationally and globally. Promoting the public knowledge and awareness of environmental problems as well as understanding of the correlations among living environment, resources, and humans through education would absolutely be urgent for educators. Campus environment is the best place for students’ ecological education and learning; therefore, a campus with good ecological environment would to-some-degree assist in the overall campus ecology. To maintain the overall balance between campus ecological environment and biological conservation, build natural landscape, and create aquatic and terrestrial habitats, traditional ecological environment engineering should be regulated to suit the sustainable development of ecological campus environment with biological conservation and ecological restoration environment. With college students in Guangxi as the research objects, total 288 students from two classes each in universities, as the experimental research objects, are preceded the 16-week (3 hours per week for total 48 hours) experimental teaching research. The research results conclude that 1.campus ecological environment integrated art education would affect learning motivation, 2.campus ecological environment integrated art education would affect learning effectiveness, 3.learning motivation presents significantly positive effects on learning effect in learning effectiveness, and 4.learning motivation shows remarkably positive effects on learning gain in learning effectiveness. According to the results to propose suggestions, it is expected to establish students’ identification and the successive belongingness through environmental integrated art education to assist students in overcoming the personality development stage for the positive psychological development.
A Review of Multicultural Education in Northern Cyprus and Turkish Learning Levels of Students from Different Cultural Backgrounds
Authors: OZBILGEHAN Mehmet , CELENK Suleyman
Published: June 2021

The purpose of this research is -within the frame of opinions by form teachers working in primary schools in Northern Cyprus- reviewing problems faced by the students coming from different cultural backgrounds and reviewing proposals to solve such problems, in addition to considering Turkish grades on foreign students’ report cards to determine Turkish learning levels of them. This study was carried out using a mix of qualitative and quantitative research methods as a base to understand the present situation. Within the scope of the purposeful sampling in the research, 40 classroom teachers from 5 primary schools from the Nicosia area were reached by using criterion sampling and maximum diversity techniques. A total of 120 foreign students were also reached. Open-ended questions were asked to teachers through semi-structured interview forms. The answers were interpreted by thematicizing. As a result of the study, problems faced by students from different cultures according to the opinions of teachers were grouped as; educational problems, communication problems, curriculum problems, problems related to family, and general problems. It is suggested to have special language programs for students from different cultural backgrounds.
Utilizarea tehnologiei informației și comunicării de către copiii din România. Sinteze teoretice
Authors: Cosma Mirela-Lăcrimioara
Published: June 2021

To understand the eﬀects of the pandemic on research in a particular ﬁeld, we need to review the existing literature in that ﬁeld up to the pandemic period. In this sense, I have synthesized the existing Romanian literature in the ﬁeld of digital division among children in Romania. The results of this literary synthesis conﬁrm an acute lack of Romanian data and research in this ﬁeld. The pandemic has required in-depth research in this area, and the interests of researchers in the eﬀects of digital technology on children/young people, have become imperative in all areas, especially education.
Effect of Reward, Work Environment, and Motivation towards Performance of the Millennial Generation in the Central Bureau of Statistics of East Kalimantan Province
Authors: MT Indah Cahyani , Rahmawati  , Milwan
Published: June 2021

A success of a work organization is strongly influenced by employee performance. To achieve this success requires a strong foundation from its employees, including the motivation that can be supported from the work environment and awards given by the organization. For the Central Bureau of Statistics in the Province of East Kalimantan, this is a challenge to achieve higher work performance and compete with other districts / cities in Indonesia. This study aims to analyze the influence of the work environment and appreciation of motivation and the effect of motivation on performance on Millennial Generation within the Central Bureau of Statistics of East Kalimantan Province. The population in this study were all employees of the Central Bureau of Statistics of East Kalimantan Province. Whereas the sample are employees of the Central Bureau of Statistics of East Kalimantan Province with age constraints of 25-40 years (129 samples). The data was collected using an electronic questionnaire to the respondents. To answer the problems in research and testing of research hypotheses, it uses Structural Equation Modeling (SEM) analysis by using Partial Least Square (PLS) with the help of SmartPLS 3.0 software. The results of this study indicate that (1) award influences motivation on Millennial Generation in the environment of Central Bureau of Statistics of East Kalimantan Province (2) work environment influences motivation on Millennial Generation in the environment of Central Bureau of Statistics of East Kalimantan Province (3) motivation influences performance on Millennial Generation in the environment of Central Bureau of Statistics of East Kalimantan Province (4) awards, work environment, and motivation affect the performance of the Millennial Generation in the environment of Central Bureau of Statistics of East Kalimantan Province.
Organizational Citizenship Behavior on Nurses : The Role of Organizational Climate and Commitment
Authors: Adnans Abdhy Aulia , Hadiyani Sherry , Zahreni Siti , Fahmi Fahmi
Published: June 2021

Abstract

Hospitals in organizing excellent quality health services require human resources committed to the organization and a positive and conducive organizational climate. This study aims to determine the effect of organizational climate and organizational commitment to organizational citizenship behavior of nurses at USU Hospital. In this study, there are two independent variables: organizational climate and organizational commitment, and one dependent variable: organizational citizenship behavior. This research is quantitative research conducted using samples from the population of nurses at USU Hospital, where a sample of 125 nurses was obtained. The data analysis method used in this study is a statistical analysis with multiple regression analysis methods. Findings. The result of this study indicates a simultaneous influence between organizational climate and organizational commitment to organizational citizenship behavior.
The Influence of Pay Satisfaction, Job Satisfaction, Competence, and Turnover Intention on the Service Quality of Honorary Employees in the Airport Operational Unit Office of Class III North Kalimantan
Authors: Asnoni Asnoni , Sambung Roby , Milwan Milwan
Published: June 2021

The study aims to determine the effect of pay satisfaction, employee job satisfaction, and competence on turnover intention and its impact on the service quality of honorary employees. The research method is quantitative research by the survey through questionnaires. The research sample was honorary employees in the Airport Operational Unit Office of Class III Kol. RA. Bessing Malinau, Tanjung Harapan, and Nunukan who have worked for more than 1 (one) year as many as 85 employees. The sampling technique in this study is a proportionate stratified random sampling technique. This research was conducted in September 2019 to February 2020. Data were analyzed using SEM PLS analysis. The results showed that pay satisfaction and job satisfaction had a significant and positive effect on service quality. Pay satisfaction, job satisfaction, and competence had a significant and negative effect on turnover intention. The turnover intention had a significant and negative effect on service quality. Pay satisfaction had a significant and indirect positive effect on service quality through turnover intention. Job satisfaction and competence did not have a significant indirect effect on service quality through turnover intention. Evaluation of employee satisfaction and competence in the organization is important to be carried out regularly. The most important thing is that this research will contribute to the body of knowledge,  especially in human resource management science.
Synthetic Life and the Value of Life
Authors: Persson Erik
Published: June 2021

If humans eventually attain the ability to create new life forms, how will it affect the value of life? This is one of several questions that can be sources of concern when discussing synthetic life, but is the concern justified? In an attempt to answer this question, I have analyzed some possible reasons why an ability to create synthetic life would threaten the value of life in general (that is, not just of the synthetic creations), to see if they really give us reason to worry. The main conclusion is that it is unlikely that a future human ability to create life will really have a great negative impact on these characteristics of life. It therefore seems unlikely that the value of life will be negatively affected by the ability to create synthetic life, though it is possible that the properties in question will be less salient in the synthetic life and thus that the value of the synthetic life will be lower than that of existing life, which in turn can lead to a disturbing difference in value between different kinds of life.
Toward an Intelligent Driving Behavior Adjustment Based on Legal Personalized Policies Within the Context of Connected Vehicles
Authors: Outay Fatma , Jabeur Nafaa , Haddad Hedi , Bouyahia Zied , Gharrad Hana
Published: June 2021

The advent of Connected Vehicles (CVs) is creating new opportunities within the transportation sector. It is, indeed, expected to improve road traffic safety, enhance mobility, reduce fuel consumption and gas emissions, as well as foster economic growth via investments and jobs. However, to motivate the deployment of CVs and maximize their related benefits, policymakers must create appropriate neutral legal frameworks. These frameworks should promote the innovation of current road infrastructures, support cooperation and interoperability between transportation systems, and encourage fair competition between companies while upholding consumer privacy as well as data protection. We argue that policymakers should also support innovative mobility services toward a better accommodation of individual drivers and vehicles. Within this scope, we are proposing in this paper an intelligent approach that promotes the implementation of personalized road policies based on driving behaviors, driving performance, and the ongoing road traffic situation. These policies, which are dynamic in space and time, ultimately aim to increase drivers’ awareness by encouraging behavioral self-regulation. To meet our goals, we are using software agents that autonomously manage the driving behaviors according to well-defined transitions between driving states while enabling appropriate message exchanges between CVs. We run software simulations as well as field tests and obtained promising results that would reflect the relevance of implementing our vision of personalized policies.
Junctional ER Organization Affects Mechanotransduction at Cadherin-Mediated Adhesions
Authors: Joy-Immediato Michelle , Ramirez Manuel J. , Cerda Mauricio , Toyama Yusuke , Ravasio Andrea , Kanchanawong Pakorn , Bertocchi Cristina
Published: June 2021

Cadherin-mediated adhesions (also known as adherens junctions) are adhesive complexes that connect neighboring cells in a tissue. While the role of the actin cytoskeleton in withstanding tension at these sites of contact is well documented, little is known about the involvement of microtubules and the associated endoplasmic reticulum (ER) network in cadherin mechanotransduction. Therefore, we investigated how the organization of ER extensions in close proximity of cadherin-mediated adhesions can affect such complexes, and vice versa. Here, we show that the extension of the ER to cadherin-mediated adhesions is tension dependent and appears to be cadherin-type specific. Furthermore, the different structural organization of the ER/microtubule network seems to affect the localization of ER-bound PTP1B at cadherin-mediated adhesions. This phosphatase is involved in the modulation of vinculin, a molecular clutch which enables differential engagement of the cadherin-catenin layer with the actomyosin cytoskeleton in response to tension. This suggests a link between structural organization of the ER/microtubule network around cadherin-specific adhesions, to control the mechanotransduction of adherens junctions by modulation of vinculin conformational state.
Syne2b/Nesprin-2 Is Required for Actin Organization and Epithelial Integrity During Epiboly Movement in Zebrafish
Authors: Li Yu-Long , Cheng Xiao-Ning , Lu Tong , Shao Ming , Shi De-Li
Published: June 2021

Syne2b/nesprin-2 is a giant protein implicated in tethering the nucleus to the cytoskeleton and plays an important role in maintaining cellular architecture. Epiboly is a conserved morphogenetic movement that involves extensive spreading and thinning of the epithelial blastoderm to shape the embryo and organize the three germ layers. Dynamic cytoskeletal organization is critical for this process, but how it is regulated remains elusive. Here we generated a zebrafish syne2b mutant line and analyzed the effects of impaired Syne2b function during early development. By CRISPR/Cas9-mediated genome editing, we obtained a large deletion in the syne2b locus, predicted to cause truncation of the nuclear localization KASH domain in the translated protein. Maternal and zygotic syne2b embryos showed delayed epiboly initiation and progression without defects in embryonic patterning. Remarkably, disruption of Syne2b function severely impaired cytoskeletal organization across the embryo, leading to aberrant clustering of F-actin at multiple cell contact regions and abnormal cell shape changes. These caused disintegration of the epithelial blastoderm before the end of gastrulation in most severely affected embryos. Moreover, the migration of yolk nuclear syncytium also became defective, likely due to disorganized cytoskeletal networks at the blastoderm margin and in the yolk cell. These findings demonstrate an essential function of Syne2b in maintaining cytoskeletal architecture and epithelial integrity during epiboly movement.
Stepwise Induction of Inner Ear Hair Cells From Mouse Embryonic Fibroblasts via Mesenchymal- to-Epithelial Transition and Formation of Otic Epithelial Cells
Authors: Yang Qiong , Shi Haosong , Quan Yizhou , Chen Qianqian , Li Wang , Wang Li , Wang Yonghui , Ji Zhongzhong , Yin Shan-Kai , Shi Hai-Bo , Xu Huiming , Gao Wei-Qiang
Published: June 2021

Although embryonic stem cells or induced pluripotent stem cells are able to differentiate into inner ear hair cells (HCs), they have drawbacks limiting their clinical application, including a potential risk of tumourigenicity. Direct reprogramming of fibroblasts to inner ear HCs could offer an alternative solution to this problem. Here, we present a stepwise guidance protocol to induce mouse embryonic fibroblasts to differentiate into inner ear HC-like cells (HCLs) via mesenchymal-to-epithelial transition and then acquisition of otic sensory epithelial cell traits by overexpression of three key transcription factors. These induced HCLs express multiple HC-specific proteins, display protrusions reminiscent of ciliary bundle structures, respond to voltage stimulation, form functional mechanotransduction channels, and exhibit a transcriptional profile of HC signature. Together, our work provides a new method to produce functional HCLs in vitro, which may have important implications for studies of HC development, drug discovery, and cell replacement therapy for hearing loss.