bluuebunny/crossref_metadata_2025 huggingface dataset:
Bioactivities and Mechanisms of Action of Diphyllin and Its Derivatives: A Comprehensive Systematic Review
Authors: Hou Wen , Huang Le-Jun , Huang Hao , Liu Sheng-Lan , Dai Wei , Li Zeng-Min , Zhang Zhen-Yu , Xin Su-Ya , Wang Jin-Yang , Zhang Zi-Yun , Ouyang Xi , Lan Jin-Xia
Published: November 2023

Natural products are treasure houses for modern drug discovery. Diphyllin is a natural arylnaphthalene lignan lactone isolated from the leaf of Astilboides tabularis. Studies have found that it possesses plenty of bioactivity characteristics. In this paper, we reviewed the structure, bioactivity, and mechanism of action of diphyllin and its derivatives. The references were obtained from PubMed, Web of Science, and Science Direct databases up to August 2023. Papers without a bio-evaluation were excluded. Diphyllin and its derivatives have demonstrated V-ATPase inhibition, anti-tumor, anti-virus, anti-biofilm, anti-inflammatory, and anti-oxidant activities. The most studied activities of diphyllin and its derivatives are V-ATPase inhibition, anti-tumor activities, and anti-virus activities. Furthermore, V-ATPase inhibition activity is the mechanism of many bioactivities, including anti-tumor, anti-virus, and anti-inflammatory activities. We also found that the galactosylated modification of diphyllin is a common phenomenon in plants, and therefore, galactosylated modification is applied by researchers in the laboratory to obtain more excellent diphyllin derivatives. This review will provide useful information for the development of diphyllin-based anti-tumor and anti-virus compounds.
Effect of Inlet Air Temperature and Quinoa Starch/Gum Arabic Ratio on Nanoencapsulation of Bioactive Compounds from Andean Potato Cultivars by Spray-Drying
Authors: Ligarda-Samanez Carlos A. , Choque-Quispe David , Moscoso-Moscoso Elibet , Pozo Lizeth M. Flores , Ramos-Pacheco Betsy S. , Palomino-Rincón Henry , Gutiérrez Rodrigo J. Guzmán , Peralta-Guevara Diego E.
Published: November 2023

Nanoencapsulation of native potato bioactive compounds by spray-drying improves their stability and bioavailability. The joint effect of the inlet temperature and the ratio of the encapsulant (quinoa starch/gum arabic) on the properties of the nanocapsules is unknown. The purpose of this study was to determine the best conditions for the nanoencapsulation of these compounds. The effects of two inlet temperatures (96 and 116 °C) and two ratios of the encapsulant (15 and 25% w/v) were evaluated using a factorial design during the spray-drying of native potato phenolic extracts. During the study, measurements of phenolic compounds, flavonoids, anthocyanins, antioxidant capacity, and various physical and structural properties were carried out. Higher inlet temperatures increased bioactive compounds and antioxidant capacity. However, a higher concentration of the encapsulant caused the dilution of polyphenols and anthocyanins. Instrumental analyses confirmed the effective encapsulation of the nuclei in the wall materials. Both factors, inlet temperature, and the encapsulant ratio, reduced the nanocapsules’ humidity and water activity. Finally, the ideal conditions for the nanoencapsulation of native potato bioactive compounds were determined to be an inlet temperature of 116 °C and an encapsulant ratio of 15% w/v. The nanocapsules obtained show potential for application in the food industry.
Ruang Virtual : Wujud Kreativitas Digital di Ruang Publik
Authors: Isfiaty Tiara , Saleh Adzkay Dani
Published: November 2023

Ruang virtual merupakan trend kreativitas ruang  yang memanfaatkan media audio visual berbasis teknologi digital. Dalam ruang virtual, teknologi digital dimanfaatkan agar pengguna ruang berkesempatan melakukan suatu aktivitas tertentu dengan tujuan mendapatkan pengalaman ruang yang berbeda dengan ruang konvensional. Pengalaman tersebut menghadirkan pengalaman ruang yang berbeda dengan ruang konvensional. Adapun keutamaan penelitian  ini adalah sebagai alternatif perancangan ruang virtual berdasarkan   karakteristik inovasi yang dapat mempengaruhi keputusan seorang individu untuk mengadopsi atau menolak suatu inovasi. Untuk itu penelitian ini bertujuan (a) mengidentifikasi karakteristik aktivitas pengguna ruang saat berpartisipasi dengan media audio visual berbasis teknologi digital (b) mengeksplorasi persepsi yang terbentuk dari pengguna ruang publik.  Penelitian menggunakan metode penelitian kualitatif sesuai dengan tujuan penelitian yang menitikberatkan pada pemahaman akan suatu pengalaman ruang digital. Hasil dari penelitian mendapatkan bahwa (a) media audio visual berbasis teknologi digital berpengaruh terhadap pola aktivitas, berupa cara duduk, frekuensi serta durasi pengguna selama berada dalam ruang digital (b) partisipan dan atraktif menjadi pola interaksi media digital dengan pengguna ruang yang merubah persepsi mereka tentang fungsi ruang publik
Pengaplikasian Hunian Green Design secara Sederhana untuk Menghadapi Dampak yang Ditimbulkan Pandemi
Authors: Anwar Hendi , Naufal Moch Fatin Abdul
Published: November 2023

Pada masa kini, sudah banyak hunian yang menerapkan konsep green design, dengan salah satu tujuan utamanya untuk mengurangi efek dari global warming. Hal ini disebabkan arsitektur merupakan salah satu penyumbang terbesar terjadinya pemanasan global. Pada tahun 2021, dengan adanya pandemi COVID-19 terjadi karantina pada populasi dunia secara massal dengan pergerakan manusia dibatasi secara masif dan hunian menjadi ruang berbagai aktivitas manusia dilakukan selama 24 jam. Hal ini terjadi akibat virus COVID-19 yang menyebar tanpa pandang bulu dan mengancam jiwa manusia terutama pada seseorang memiliki imun yang menurun. Dengan adanya pandemi yang terjadi, banyak hal yang telah dilakukan untuk mencegah penyebaran virus COVID-19. Salah satu hal yang ditemukan dalam pencegahan penyebaran virus COVID-19 bahwa konsep green design memiliki manfaat lain selain pengurangan energi dan pemanasan global juga mengurangi dampak yang ditimbulkan oleh virus COVID-19 pada hunian. Penelitian ini merupakan penelitian kualitatif yang memberikan review mengenai dampak keterkaitan antara prinsip green design dengan kesehatan manusia melalui beberapa review jurnal dan penelitian yang telah dilakukan sebelumnya, serta bagaimana cara mengaplikasikannya dalam hunian. Diharapkan pengaplikasian green design secara sederhana pada bangunan rumah tinggal ini dapat meringankan dampak yang ditimbulkan pandemi COVID-19 terutama kesehatan penghuni.
Kajian Ragam Material Rotan Dengan Sistem Modular Pada Interior Bangunan Residensial
Authors: Astuti Anggi Dwi
Published: November 2023

Rotan adalah salah satu bahan utama dalam kerajinan sederhana dan barang furnitur interior. Rotan juga memiliki nilai ekonomi sebagai produk yang layak secara komersial. Penurunan produksi rotan secara bertahap semakin terlihat baik di dalam dan di luar negeri akibatnya diversifikasi pemasaran produk harus membidik pasar yang lebih besar. Diversifikasi produk rotan juga menguntungkan desainer muda dengan meningkatkan peluang dan persaingan mereka dalam memproduksi desain panel hias berbahan rotan lokal. Penelitian ini menggali berbagai ragam material rotan yang tersedia dan mengidentifikasi karakteristik unik masing-masing jenis rotan serta potensinya dalam desain modular, sehingga panel rotan menjadi salah satu solusi terbarukan yang tepat untuk meningkatkan daya serap bahan rotan dengan teknik manufaktur yang lebih efisien. Manfaat estetika interior dari sekat pembatas ruang berbahan dasar rotan diproyeksikan dapat dimanfaatkan pada komponen interior yang beragam untuk meningkatkan citra barang-barang yang saling terhubung dan mendukung nuansa lokal dalam balutan yang lebih modern, seiring dengan maraknya bangunan hunian. Melalui karya ini diharapkan dapat menjadi sumber keilmuan bagi mahasiswa dan dapat bersaing baik secara estetika maupun fungsi.
Methodological foundations of risk analysis and assessment in the public sector
Authors: Gorokhova D. V.
Published: November 2023

The article offers the author's view on the development of risk assessment methodology in the public sector. Based on the analysis of generally accepted risk assessment methods, their comparative characteristics are given and an approach to the choice of risk assessment methods depending on groups of uncertainty factors is proposed. Due to the insufficiency of statistical and mathematical risk assessment tools, emphasis is placed on the system of calculation and analytical coefficients, in part of which an approach to the system of risk assessment indicators is proposed, depending on the type of public sector organization. Special attention is paid to the issue of determining an acceptable level of risk and a methodology for calculating it is proposed.
“Interrogar y hasta modificar el pasado”: la historia literaria en Borges
Authors: Premat Julio
Published: November 2023

En el artículo se asocia la práctica fundadora de una “manera Borges” de narrar (la invención de libros y de autores) con una práctica asidua de fabulación de historia literaria. Con diferentes procedimientos Borges reinventa la historicidad de la literatura, la sucesión de obras y las marcas de la influencia, esbozando un relato alternativo al entonces dominante. En los primeros tres ejemplos de ese tipo de relatos (“El acercamiento a Almotásim”, “Pierre Menard, autor del Quijote” y “Examen de la obra de Herbert Quain”) se constatan algunos efectos al respecto, como el de una historia no cronológica, una historia soñada, una historia utópica. Se intenta demostrar que, junto con las operaciones llevadas a cabo con la filosofía, la teología y otros saberes enciclopédicos, las variaciones imaginativas de Borges sobre y alrededor de la historia literaria fueron centrales en la definición de su obra madura.
Crítica libre
Authors: Laera Alejandra
Published: November 2023

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Federated Generative-Adversarial-Network-Enabled Channel Estimation
Authors: Guo Yiyu , Qin Zhijin , Tao Xiaoming , Dobre Octavia A.
Published: November 2023

Accurately estimating channel state information is essential for meeting the quality-of-service requirements of modern applications and scenarios. Deep learning techniques have proven effective in acquiring channel conditions with low pilot overhead in massive connectivity scenarios. However, accessing channel data brings new challenges related to transmission overhead, privacy concerns, scalability, heterogeneous network support, and adaptability to dynamic environments. We propose a federated generative-adversarial-network-enabled channel estimator to address these challenges. We refine the coarse least-squares estimation results for their low complexity and fast convergence. To ensure accuracy, we designed a double U-shaped network. The Lipschitz continuous function is applied to discriminators for spectral normalization. We then propose a federated learning framework to utilize the training process. The local generator parameters are updated at the center, reducing communication overhead and privacy concerns. To deal with nonindependent and identically distributed datasets, the discriminators dynamically push away the predictions by dynamic regularization to obtain a more robust aggregated generative model at the center. Furthermore, we propose a motivation scheme that benefits users participating in the training process, encouraging them to join and take advantage of edge/cloud computing capabilities. Numerical results demonstrate that the proposed federated generative adversarial network-enabled channel estimator provides high estimation accuracy and reduces the burden on pilots. The proposed dynamic regularization terms and motivation scheme boost performance efficiently with low communication cost and high participation.
Enhanced Offshore Wind Speed Forecasts along the US East Coast: A Deep Learning Framework Leveraging NDBC Buoy Data
Authors: Han Xinhai , Li Xiaohui , Yang Jingsong , Wang Jiuke , Ding Jun , Shen Hui , Yan Jun , Fang He , Xiao Qingmei
Published: November 2023

Offshore wind speed is a critical factor that influences various aspects of human life, and accurate forecasting is of utmost importance for the efficient utilization of offshore resources. In this paper, we present a novel deep-learning-based model for multisite offshore wind speed forecasting along the US East Coast. The proposed model is trained using the collected 2018–2020 National Data Buoy Center buoy data and tested using the 2021–2022 data. By inputting historical wind speed data into the model, simultaneous forecasting results can be obtained for multiple buoy sites through the embedding layer, feature extraction layer, and long short-term memory layer. Notably, the embedding layer, which is specifically engineered to capture spatial dependencies between multiple sites, proves to be highly effective in the context of multisite wind speed forecasting, as substantiated by our conducted ablation experiments. The evaluation metrics display satisfactory results: The 12-h average root mean square error at 1-h forecasting intervals is 2.09 m/s, the correlation coefficient is 0.7, and the mean absolute error is 1.24 m/s. Through case studies, the proposed model demonstrates its effectiveness in forecasting wind speeds during hurricanes, underscoring its potential for use in the offshore wind energy assessment and maritime disaster warning domains.
Organisationale Transformation in Non-Profit-Organisationen
Authors: Röhrig Michelle
Published: November 2023

Die Ergebnisse der empirischen Untersuchung zeigen, dass durchaus nennenswerte Unterschiede zwischen Non-Profit-Organisationen und For-Profit-Organisationen bestehen, die sich auch auf Transformationsvorhaben auswirken. Daraus resultieren spezielle Anforderungen von Non-Profit-Organisationen an eine Transformation, die ausreichende Beachtung finden sollten. So werden die besten Voraussetzungen geschaffen, damit eine Transformation in Non-Profit-Organisationen die gesetzten Ziele erreicht, gegebenenfalls ungeplante Potenziale ausschöpft und Risiken umgeht. Non-Profit-Organisationen arbeiten in einem speziellen Spannungsfeld. Dabei könnte man von einer ≫Ambidextrie der Non-Profit-Organisationen≪ sprechen, bei der sowohl die Professionalisierung und Effizienz auf der einen Seite als auch die Sozialität und das Ehrenamt auf der anderen Seite möglichst in Balance gehalten werden sollen. Allein diese Ambidextrie macht es erforderlich, dass sich die Organisationen stets selbst hinterfragen, ihr Umfeld kontinuierlich beobachten und bei Bedarf Transformationsvorhaben einleiten. Bei der Betrachtung der zahlreichen weiteren Einflüsse auf Non-Profit-Organisationen sowie deren Herausforderungen wird klar, dass organisationale Transformation ein unumgängliches Thema für Non-Profit-Organisationen ist.
A vessel visualization system in a surgical wound with massive bleeding
Authors:   Institute of Computational Modelling SB RAS, Medievsky A.V. , Zotin A.G. , Simonov K.V. , Cherepanova T.V. , Khomkolov I.V. ,   Institute of Space and Information Technologies SibFU
Published: November 2023

The work is devoted to the development of a system for visualizing vessels in a surgical wound with massive bleeding to improve the observation of structures in the surgical field. A modification of the video endoscope and the method of illumination of the surgical wound is proposed. At the same time during the development of a video endoscopic system the ability to operate in near infrared and color modes is taken into account. As part of the experiments an analysis was made of the quality of visualization of biological structures depending on the depth of their location in the surgical wound. As a result a system and methodology have been created that improve the quality of visualization of blood vessels under bleeding conditions. The results obtained can be applied in endoscopic surgery.
Analisis Ekonomi Sayuran Hidroponik (Studi Kasus PT. Hidrotani Sejahtera, Kecamatan Sunggal Kabupaten Deli Serdang, Sumatera Utara)
Authors: Lubis Siska Yulianita , Balatif Fuad , Hakim Mukti , Darmawan Panji
Published: November 2023

Berdasarkan hasil dan pembahasan analisis yang telah diuraikan, komponen biaya tetap yang tertinggi terdapat pada komoditas Pakcoy dengan total biaya tetap sebesar Rp.12.290.829 perbulan sedangkan komponen biaya tetap terendah yaitu pada komoditas Selada dengan total biaya tetap Rp.1.268.296 perbulan. Total biaya produksi PT Hidrotani Sejahtera tertinggi terdapat pada komoditas Pakcoy sebesar Rp. 14.529.329 perbulan. Penerimaan yang didapatkan PT Hidrotani Sejahtera sebesar Rp.37.750.000 dari semua jenis sayuran yang diproduksi dalam satu bulan. Penerimaan PT Hidrotani Sejahtera didapat harga jual sayuran hidroponik yang lebih tinggi dibandingkan dengan harga sayuran konvensional di pasar. Harga sayuran yang tinggi mampu menutupi biaya operasional produksi yang tinggi pada perusahaan. Keuntungan yang diterima PT Hidrotani Sejahtera dalam satu bulan mencapai Rp. 6.497.558. Keuntungan dan efisiensi ditunjukkan oleh besarnya keuntungan yang didapatkan setiap bulannya dan nilai efisiensi usaha (R/C Ratio) yang lebih dari satu pada semua jenis sayuran yang di produksi yaitu 1,12 – 1,27. Komoditas sawi putih merupakan komoditas yang paling efisien. Sehingga dapat disimpulkan bahwa usaha sayuran hidroponik PT Hidrotani Sejahtera layak untuk dikembangkan.
Pengaruh Faktor–Faktor Produksi Terhadap Produksi Padi Sawah (Studi Kasus : Desa Pasar Miring Kecamatan Pagar Merbau Kabupaten Deli Serdang)
Authors: Baldan Panjaitan Faisal Azhari , Balatif Fuad , Sumiati Sumiati
Published: November 2023

Faktor yang menyebabkan penurunan produksi adalah karena belum optimalnya penggunaan faktor-faktor produksi seperti luas lahan, bibit, pupuk, tenaga kerja dan pestisida. tujuan penelitian yang akan diteliti adalah sebagai berikut : (1)untuk menganalisis pengaruh faktor produksi luas lahan terhadap produksi padi di daerah penelitian. (2) untuk menganalisis pengaruh faktor produksi benih terhadap produksi padi di daerah penelitian. (3) untuk menganalisis pengaruh faktor produksi pupuk terhadap produksi padi di daerah penelitian. Model analisis yang digunakan dalam penelitian ini adalah model regresi berganda.   Secara parsial variabel  luas  lahan (X1),  berpengaruh  signifikan  terhadap  produksi padi sawah di daerah penelitian, sedangkan variabel benih (X2) berpengaruh  tidak  signifikan  terhadap  produksi padi sawah di daerah peneltian.Variabel pupuk (X3) berpengaruh signifikan terhadap produksi padi sawah di daerah penelitian. Secara simultan pengaruh variabel bebas luas lahan (X1), Benih (X2) dan Pupuk (X3) terhadap produksi padi sawah didaerah penelitian menunjukkan berpengaruh signifikan terhadap variabel produksi (Y).
A Novel Additive Internet of Things (IoT) Features and Convolutional Neural Network for Classification and Source Identification of IoT Devices
Authors: IORLİAM Aamo
Published: November 2023

The inter-class classification and source identification of IoT devices has been studied by several researchers recently due to the vast amount of available IoT devices and the huge amount of data these IoT devices generate almost every minute. As such there is every need to identify the source where the IoT data is generated and also separate an IoT device from the other using on the data they generate. This paper proposes a novel additive IoT features with the CNN system for the purpose of IoT source identification and classification. Experimental results shows that indeed the proposed method is very effective achieving an overall classification and source identification accuracy of 99.67 %. This result has a practical application to forensics purposes due to the fact that accurately identifying and classifying the source of an IoT device via the generated data can link organisations/persons to the activities they perform over the network. As such ensuring accountability and responsibility by IoT device users.
Legal Incentives and Obstacles to Corporate Social Responsibility in Slovenia, the EU and Globally
Authors:   Science and Research Centre Koper, Slovenia, Bohinc Rado
Published: November 2023

Corporate social responsibility (CSR), or responsible business conduct as a tool of sustainable development (green transition) and respect for human rights in the economy is getting more and more legally based. In different countries, the legal levers of CSR are very diverse; since this creates unequal conditions in the global market, the harmonization of the CSR related rules is essential. Important for the legal regulation of CSR is the proposal for the EU Corporate sustainability due diligence directive, CSDDD); among other things, the proposal expands the due diligence of directors from acting in the best interest of the company, also to consider the risks that threaten sustainable development and human rights, and in this regard sharpens corporate liability for damages. Key shifts in CSR can only be ensured by binding corporate law rules on directors’ due diligence and corporate damage liability for sustainability and human rights violations. The integration of environmental, social and governance (ESG) factors into investments is an increasingly common feature of modern CSR concept. Only environmental and labor legislation alone are not sufficient for the implementation of sustainable development and CSR. Interventions in corporate legislation are needed. In the EU, the implementation of CSR has so far been voluntary; only sustainability (non-financial) reporting is mandatory. The proposal of the CSDDD is therefore ground-breaking, as it intervenes for the first time in corporate legislation in favor of sustainable development, namely in regulating the sustainability civil liability of companies and the due diligence of directors. However, political debates between the EC, the Council and the EP due to differences in views about the latter are still ongoing. Slovenia (the government or Parliament) must finally adopt the National Plan for the enforcement of corporate social responsibility, as stipulated by the EU Commission already in the Revised Strategy 2011. In the legislation governing the operation of corporations (ZGD-1), Slovenia must establish the obligation of sustainable due diligence, to determine the duty of adopting a social responsibility strategy in every company and to determine, as a duty of care of directors, also the consideration of sustainability goals and CSR.
THE CONSTRUCTION AND PRACTICE OF COMMUNITY CRISIS INFORMATION MINING MODEL ON THE WECHAT INTERNET PLATFORM RESEARCH
Authors: Cheng Zeng
Published: November 2023

Mining community crisis information on Internet platforms is a complex project. This study focuses on theoretical review, subject intervention, and practical research from a management perspective. The goal is to optimize the model of WeChat Internet community information governance and propose a mining search and extraction method for community public opinion information in social networks. The study aims to effectively manage traditional public opinion information in terms of search, cleaning, extraction, storage, and more. The research also designs a search system structure for community information and establishes a public opinion information mining model based on the audience's personalized behavior search method.
THE LEARNING MANAGEMENT WITH TIKTOK MEDIA FOR ENGLISH SPEAKING SKILLS OF GRADE 7 CHINESE STUDENTS IN YUNNAN PROVINCE, CHINA
Authors: Wang Yuetong , Pianchana Techameth
Published: November 2023

This research aims to study the learning management with TikTok media for English speaking skills of grade 7 Chinese students in Yunnan Province, China. The researcher investigated whether the use of TikTok media improved the English speaking skills of 30 grade 7 Chinese students and further explored their satisfaction. The cluster random sampling was conducted to select the sample from two grade 7 classes in a middle school. The quantitative data were collected using speaking skill tests (pretest and post-test), and the student satisfactions collected from questionnaires were analyzed and interpreted using inferential statistics (t-test) with p≤0.05 significance, mean, and standard deviation. The results revealed that the mean score of the pretest is 10.73; the mean score of the posttest is 17.20; and the mean difference is 6.46. In addition, the obtained p-value is .01. The results showed that post-test scores were higher compared to the pretest scores, and the student satisfaction was also positive. Therefore, the results of the study revealed that TikTok media could improve the English speaking skills of the students and also their satisfaction.
FACTORS INFLUENCING UNDERGRADUATE STUDENTS' INTENTION TO USE ONLINE EDUCATION PLATFORMS
Authors: Feng Lijuan , Li Changhan
Published: November 2023

The aim of this study is to examine the factors influencing intention to use e-learning platforms in universities in Sichuan, China. Research design, data and methodology: Quantitative methods and data collection A questionnaire was used as a tool to collect sample data. Prior to distributing the questionnaires, the content validity and reliability were assessed using Item-Objective Congruence and pilot testing. Goodness of model fit was analyzed by confirmatory factor analysis and structural equation modeling, and causal relationships between variables were determined for hypothesis testing.

The study found that the conceptual model was able to predict behavioral intention (BI) to use mobile educational platforms in higher education, and that perceived ease of use (PEU) and attitude towards use (ATT) were the two key antecedents of behavioral intention to use mobile educational platforms.

It is concluded that ATT is the strongest factor in direct BI use and that social influence, convenience and expected performance have a significant effect on ATT. Therefore, this study suggests that mobile educational platform developers and higher education administrators should focus on improving the usability factors of mobile educational platforms so that students find the platform useful and further develop good attitudes and behavioral intentions to use mobile educational platforms.
THE RELATIONSHIP BETWEEN COLLEGE STUDENTS' SOCIAL SUPPORT AND NETWORK DEPENDENCY RESEARCH
Authors: Lan Qiandong , Gao Yimin
Published: November 2023

In the information age, the penetration rate of the network is deepening day by day, and college students are becoming one of the groups with high usage rates of the network. College students use the Internet to search for information, browse information, send and receive emails, chat and make friends, play games, and watch live broadcasts. The network has become an important part of college students' studies. However, while the Internet brings a lot of convenience to college students, it also causes many college students to rely on or even become addicted to the Internet. This problem not only has a negative impact on the physical and mental growth of college students but also becomes a practical management problem faced by universities and even the whole education field. Based on summarizing relevant research at home and abroad, this study uses a questionnaire survey and statistical analysis to carry out empirical research. Taking college students in H university as the research object, 502 valid questionnaires were collected. Through regression and mediating analysis, the theoretical hypothesis that college students' social support has a negative effect on Internet dependence and that college students' social efficacy plays a mediating role in the process of social support's influence on Internet dependence was verified. The mediating model of college students' social support, social efficacy, and network dependence was constructed. From the perspectives of family, school, society, and individual students, the research also puts forward some suggestions to reduce college students' Internet dependence and cultivate the correct concept of the Internet.
THE DEVELOPMENT OF A MODEL TO ENHANCE STUDENT TRANSFORMATIONAL LEADERSHIP SKILLS FOR APPLICATION-ORIENTED UNIVERSITIES IN SHANXI PROVINCE, CHINA
Authors: Li Mengyan , Merritt Matthew Reed
Published: November 2023

In this research, the primary purpose was to create a model for developing transformational leadership skills for application-oriented university students in Shanxi, China. The aim was to help college students smoothly enter society and have better career prospects. This study utilized qualitative and quantitative methods, conducting content analysis on ideal AOUs student transformational leadership skills, which include a sense of responsibility, self-dedication, vision, teamwork, innovation, problem-solving skills, communication, and listening. The results of the content analysis were validated by five experts. The study also collected 1,002 survey questionnaires from AOUs students in Shanxi, China.

The study found that five leadership activities influenced the level of transformational leadership skills: participation in leadership workshops, students’ councils, student clubs, volunteer activities, and social practice activities. Additionally, the study highlighted the similarities between Chinese Confucian thought and Western transformational leadership theory. The four philosophical ideas of Confucianism were found to be applicable in understanding Western leadership theories and guiding students' participation in related activities. The recommendations emphasize the prioritization of transformational leadership skills by stakeholders, recognizing their broad utility and crucial role in students' future success.
Collaboration Between Parents and Teachers in Overcoming Arabic Language Learning Difficulties Among Children at Min Paya Seunara Sabang
Authors: Sarmiwida
Published: November 2023

The mastery of the Arabic language is essential for Indonesia's individuals to meet global challenges. While formal Arabic language programs in Madrasah serve as a primary means for Indonesian children, students at MIN Paya Seunara, Sabang City, face difficulties in learning Arabic. This research explores the collaborative strategies employed by parents and teachers to address these challenges. The study aims to understand the approaches used by parents and teachers in overcoming Arabic language learning difficulties among students. It investigates whether parents and teachers provide attention, guidance, and necessary resources to alleviate and prevent learning obstacles, especially in Arabic language studies. The research, utilizing a descriptive methodology involving literature review and field research, includes 50 students, 1 principal, 1 Arabic language teacher, and 40 parents at MIN Paya Seunara. Findings suggest that positive collaboration between parents and teachers significantly influences students' academic progress. Efforts such as providing support, sufficient learning resources, and guidance play a crucial role. The study concludes that effective collaboration between parents and teachers is instrumental in addressing Arabic language learning challenges. Recommendations include increasing the number of teachers and fostering closer collaboration between school staff and parents for an enhanced educational process.
The Implementation of Religious Education to Support the Socialization of Islamic Sharia at Sabang City
Authors: Rosnaini
Published: November 2023

The implementation of Islamic Sharia, particularly in the Aceh region, is considered obligatory. The community bears a moral responsibility to support the socialization of Islamic Sharia. This responsibility falls upon various stakeholders, including teachers, parents, and members of the community. Among these stakeholders, teachers are crucial in imparting religious education both at schools and within the home environment, while the broader community plays a significant role. This thesis explores the execution of religious education in supporting the socialization of Islamic Sharia, with the aim of understanding how Islamic religious education is implemented to foster the acceptance of Sharia principles in the city of Sabang. Additionally, the study seeks to identify the factors influencing the implementation of Islamic Sharia. The research methodology employs a descriptive research method, incorporating both literature review and field research techniques such as observation, interviews, and questionnaires. The study involves a sample of 50 students from MTsN Sabang, school principals, religious studies teachers in both public and religious schools, and a segment of the local community, particularly parents in the city of Sabang. The findings indicate that the implementation of religious education to support the socialization of Islamic Sharia in Sabang is carried out through instructing students on Islamic teachings, encompassing creed, worship, and ethics. Emphasis is placed on guidance regarding the obligation to observe modest dress, perform the five daily prayers, and attend Friday prayers. These teachings are conducted through discussions during Islamic studies in schools. Various factors influencing the implementation of Islamic Sharia include all components of society—teachers, parents, and the surrounding community—especially local leaders. Challenges persist, such as adherence to local customs, insufficient understanding of Islamic Sharia, and disparities in understanding among scholars and religious authorities. Efforts to enhance religious education for the socialization of Islamic Sharia in Sabang include increased teaching hours dedicated to religious studies. This allows for more in-depth exploration and discussions on Islamic Sharia. Recommendations are directed towards teachers to improve their instruction on Islamic teachings and to school principals to allocate specific time for students to discuss Sharia principles. Parents are urged to continuously remind their children to adhere to the implementation of Islamic Sharia.
Evaluation of the Impact of Using Technology in Physical Education Learning at Serambi Mekkah University
Authors: Suardi
Published: November 2023

This research aims to evaluate the impact of using technology in Physical Education learning in the Serambi Mekkah University environment. To integrate technology in the Physical Education curriculum, this research identifies its potential impact on student participation, achievement of learning outcomes, and improvement of physical well-being. The research method involved a literature review to detail the theoretical foundation, a needs analysis to understand the status of the Physical Education program at the university, and the implementation of technology-based interventions in learning. This research makes a significant contribution to the understanding of the effectiveness of applying technology to improve Physical Education learning, especially in the context of Serambi Mekkah University. Data collected through surveys, interviews and observations will be analyzed comprehensively to evaluate the effectiveness of the technology integration. It is hoped that the results of this research can provide valuable insight for the development of better learning policies and practices in supporting physical education, health, and recreation in higher education environments. Through an in-depth understanding of the impact of using technology in Physical Education learning, it is hoped that this research can provide concrete and effective recommendations for improving the quality of physical education at Serambi Mekkah University. As a higher education institution, the implementation of technology in the learning process can be the key to stimulating student engagement, increasing understanding of Physical Education concepts, and strengthening aspects of physical well-being. Therefore, it is hoped that the findings from this research will pave the way towards the development of innovative learning policies and strategies at university level, as well as stimulate further discussion about the role of technology in physical education.
PACIENTŲ NUOMONĖ APIE NUOTOLINIU BŪDU FARMACIJOS SPECIALISTŲ TEIKIAMOS FARMACINĖS PASLAUGOS SVARBĄ
Authors: Ančiūnienė Milita , Pockevičiūtė-Tarasovė Birutė , Motienė Regina , Galkontas Aurimas
Published: November 2023

Išmaniosios technologijos vis labiau keičia pacientų apsipirkimo įpročius. Pacientų pirkimo patirtį pakeitė ne tik internetas, bet ir nauji išmanieji komunikaciniai įrenginiai. Lietuvoje nuo 2015 metų gruodžio pradėta parduoti nereceptinius preparatus nuotoliniu būdu. Nuo 2022 metų liepos nuotoliniu būdu galima įsigyti vaistinių receptinių preparatų ir medicinos pagalbos priemonių (MPP) su elektroniniais receptais, prieš tai suteikus nuo­tolinę farmacinę paslaugą komunikacinėmis nuotolinio ryšio priemonėmis. Prieš įsigyjant vaistinius preparatus, nuotoliniu būdu teikiamos farmacijos specialistų farma­cinės paslaugos. Farmacijos specialistų konsultacijos ir farmacinių paslaugų teikimas pacientams yra būtini veiksniai, norint padėti tinkamai vartoti vaistinius pre­paratus. Nuotolinių vaistinių poreikis ypač išaugo 2019 metais, prasidėjus COVID-19 pandemijai, kai pacientams nuotoliniu būdu teikiamos farmacijos specialistų farma­cinės paslaugos buvo patogiausias pasirinkimas. Aktualu atskleisti pacientų nuomonę apie farmacijos specialistų teikiamų nuotolinių farmacinių paslaugų svarbą, nes, jų nesant, reikalingų vaistinių preparatų į namus ar į kitą pasirinktą vietą gauti negalima. Tyrimo objektas – paci­entų nuomonė apie nuotoliniu būdu farmacijos specialistų teikiamos farmacinės paslaugos svarbą. Tyrimo tikslas – atskleisti pacientų nuomonę apie nuotoliniu būdu farma­cijos specialistų teikiamos farmacinės paslaugos svarbą. Empirinio tyrimo metu nustatyta, kad farmacijos speci­alistams teikiant nuotoliniu būdu farmacinę paslaugą, įžvelgiama daug privalumų, tačiau pasitaiko ir trūkumų. Pacientams, nuotoliniu būdu įsigyjantiems vaistinius preparatus, ne visada suteikiama reikalinga informacija apie vaistinį preparatą, jo sąveiką su kitais vaistiniais preparatais, ne visuomet supažindinama su vaistų šalu­tiniu poveikiu. Nuotoliniu būdu farmacijos specialistų teikiama farmacinė paslauga pacientams yra labai svarbi, tačiau dažnesniu atveju vertinama kaip mažiau efektyvi, nei visuomenės vaistinėse teikiama farmacinė paslauga. Dauguma tyrime dalyvavusių respondentų nuotoliniu būdu farmacijos specialistų teikiamą farmacinę paslaugą vertina labai gerai ir teigia, kad nuotolinės vaistinės yra labai reikalingos. Didžioji dalis tyrime dalyvavusių res­pondentų sutinka, kad nuotolinė farmacinė paslauga yra svarbi, neatsižvelgiant į tai, ar perkami vaistiniai prepa­ratai yra receptiniai ar nereceptiniai.
PACIENTŲ, KURIEMS TAIKOMA INTENSYVIOJI SLAUGA, KOMFORTAS
Authors: Smaidžiūnienė Dalė , Čekavičiūtė Irmida , Jarašiūtė Viktorija
Published: November 2023

Intensyviai slaugomų pacientų komfortas ar diskomfortas yra svarbus paciento patirties gydymo įstaigoje veiksnys, reikšmingas vertinant gydymo bei slaugos kokybę. Ty­rimo tikslas − įvertinti pacientų, kuriems taikoma in­tensyvioji slauga, komfortą. Tyrimui atlikti naudotas K. Kolcaba sukurtas „Bendrasis komforto klausimynas“.

Tyrimo dalyviai. III ir IV kurso bendrosios praktikos slaugos studijų studentai profesinės praktikos metu įver­tino 44 pacientų, besigydančių reanimacijos ir intensyvio­sios terapijos skyriuose, komforto atvejus. 82 studentai atsakė į klausimyno autorių pateiktą atvirą klausimą, į kurį atsakymai analizuoti atliekant turinio (content) ana­lizę. Nustatyta, kad dažniausiai intensyviai slaugomų pacientų komfortas buvo vidutiniškas. Iš tyrimo galime daryti prielaidas, kad nei vieno intensyviai slaugomo paciento komfortas nebuvo labai aukštas. Aukščiausiai buvo vertinama tai, kad pacientas turi kuo pasikliauti, kai jam to reikia; komfortabili kambario temperatūra reani­macijos skyriuose. Didžiausią diskomfortą kėlė pacientų priklausomybė nuo kitų asmenų, o intensyviai slaugomų − baimė dėl ateities, šalutiniai garsai, kurie trukdo ilsė­tis, gydytojo paramos trūkumas ir negalėjimas kontro­liuoti situacijos. Būsimųjų slaugytojų požiūriu, pacientų komfortą pagerintų didesnis dėmesingumas paciento poreikiams, paciento perspėjimas ir informavimas prieš procedūras, artimųjų įtraukimas, aplinkos pritaikymas paciento poreikiams, geresnis darbo organizavimas, ma­žesni slaugytojų darbo krūviai bei organizacijų kultūra, skatinanti pagarbą pacientui.
HIALURONO RŪGŠTIES INJEKCIJOS PANAUDOJIMAS SPINDULINĖS TERAPIJOS, TAIKOMOS PROSTATOS VĖŽIUI GYDYTI, KOMPLIKACIJŲ PREVENCIJAI
Authors: Kaselytė Urtė
Published: November 2023

Prostatos vėžio gydymui taikoma spindulinė terapija gali sukelti įvairių komplikacijų, kurios blogina gyvenimo kokybę. Transperininė hialurono rūgšties injekcija gali būti taikoma siekiant sukurti tarpą tarp prostatos ir ap­linkinių audinių. Sukurtas tarpas mažina aplinkinių au­dinių gaunamą spindulinę dozę, todėl sukeliama mažiau virškinamojo trakto komplikacijų. Įrodyta, kad hialurono rūgšties injekcija yra saugus ir veiksmingas būdas, ma­žinantis trumpalaikių ir ilgalaikių virškinamojo trakto komplikacijų dažnį. Yra naujų tyrimų, leidžiančių manyti, kad hialurono rūgšties injekcija gali būti naudojama sie­kiant atskirti šalia prostatos esantį neurovaskulinį pluoštą ir taip veiksmingai išsaugoti erekcijos ir ejakuliacijos funkcijas pacientams, kuriems dėl prostatos vėžio tai­koma brachiterapija.
ŽMOGAUS PAPILOMOS VIRUSO SUKELTO GIMDOS KAKLELIO VĖŽIO KLINIKA IR DIAGNOSTIKA
Authors: Trainavičienė Viltė
Published: November 2023

Tyrimo tikslas – atlikti literatūros apžvalgą apie žmogaus papilomos viruso sukelto gimdos kaklelio vėžio klinikos ir diagnostikos ypatumus.

Medžiaga ir metodai. Atliekant literatūros apžvalgą, duo­menų buvo ieškoma Medline (per PubMed) ir UpToDate duomenų bazėse. Į apžvalgą įtraukti 2017-2023 metais anglų kalba publikuoti straipsniai, atitikę paieškos kri­terijus. Atrinkti, išanalizuoti ir apibendrinti 4 straipsniai.

Tyrimo rezultatai. Klinika. Paauglystėje yra didžiausia rizika įgyti žmogaus papilomos virusą, o onkologiniai pakitimai pasireiškia vyresniame amžiuje. Dažniausiai ankstyvosios stadijos gimdos kaklelio vėžys nesukelia jokių simptomų arba sukelia nespecifinius simptomus. Vėlyvieji simptomai būdingi invazinėms vėžio formoms, kai navikas perauga pamatinę membraną. Kliniškai paci­entės gali jausti pilvo ar apatinės nugaros dalies skausmą, plintantį į kojas. Diagnostika. Atrankinis tyrimas – gim­dos kaklelio citologinis tepinėlis arba gimdos kaklelio aukštos rizikos ŽPV tyrimas – atliekamas pagal preven­cinę programą. Radus pakitimų, atliekamas kolposko­pijos tyrimas, pažeistos vietos biopsija, retais atvejais atliekama gimdos kaklelio konizacija.

Išvados. Žmogaus papilomos viruso sukeliamas gim­dos kaklelio vėžys nepasireiškia ligai specifiniais simp­tomais. Plintant navikiniam procesui, moteris pradeda jausti simptomus. Didelė reikšmė tenka diagnostiniams tyrimams, padedantiems onkologinius pakitimus nusta­tyti ankstyvose stadijose. Citologiniai atrankos tyrimai padeda identifikuoti moteris, kurioms reikalingas deta­lesnis ištyrimas.
RECURRENT ADRENOCORTICAL CARCINOMA– A CASE REPORT
Authors: Devi Seema , Kumar Abhishek , Rana Raina , Minakshi P
Published: November 2023

Incidence of Adrenocortical Carcinoma approximately 1 to 2 (1, 2) case/ million Population per year. It represents only
0.02% of all Neoplasm. It has two peak of incidence 0-5 years and 40 to 50 years of age. (3) It predominantly occurs in
Females with Male: Female ratio of (1:1.5-2.5). (4,5) Some studies suggested proliferative effects of oestrogen hormone
on malignant adrenal cells (3) The National Institute of Health office of Rare Disease, research defines rare disease as
having prevalence of less than 2,00,000 (two lakh) patients in the United States of America (8). A 37-year-old female
presented with pain in abdomen for the last 3 months, she had undergone surgery in 2019, Histopathology report came
as adrenocortical tumor. Biopsy was done which had shown malignant neoplasm, Immunohistochemistry report has
confirmed as Adrenocortical tumour. Melan-A diffuse moderate strong positive in tumour cells. Adrenocortical
carcinoma is found to be more common in the Children (11) Similar to our case report Else and colleagues also reported
unilateral involvement with the normal contra lateral adrenal gland and female preponderance. The adjuvant therapies
are advised to decrease the chances of recurrence. For unresectable or metastatic disease treatment is advisable with
palliative purpose.
WOUND ALTERATION BECAUSE OF MAGGOT ACTIVITY – A CASE REPORT
Authors: Kaur Amandeep , Joshi Rajiv , Singh Chhabra Harvinder , Singh Ravdeep
Published: November 2023

Introduction: The role of a forensic autopsy surgeon is to conclude the cause of death and to opine upon the nature of
injuries. A post-mortem artefact is any change or alteration produced in the body after death which leads to confusion
whether an injury or wound was produced antemortem. A dead body of a 65 year old lady was found in t Case Report: he
storage box of the bed of her room. Dead body was found by a relative and brought for postmortem. As dead body was
infested with maggots it was difficult to find cause of death. Many times maggots are responsible f Conclusion: or
altering the shape and size of wounds in decomposing bodies. Accurate and judicious autopsy examination is the key to
differentiate antemortem or postmortem wound and help in solving crime
ORTHODONTIC APPROACH TO PATIENTS WITH AUTISM SPECTRUM DISORDER (ASD): A REVIEW.
Authors: Leiva Dra Noemi , Martínez Consuelo , Pavez L Paula
Published: November 2023

Summary
In the last decade there has been an increase in the diagnosis of Autism Spectrum Disorder (ASD) and with it,an increase
in orthodontic care.Studies have shown that this group presents high requirements for orthodontic treatment.Although it
has been verified that the patient needs to improve dental-facial aesthetics, occlusion or oral function, a significant
percentage are not treated because of behavioral difficulties and specific needs during orthodontic care.Therefore,the
objective of this study is to suggest information and strategies necessary for the orthodontic care of patients with ASD in
order to facilitate the treatment process.
THE PREVALENCE OF BREAST CANCER DIFFERENT MOLECULAR SUBTYPES IN GEORGIAN WOMEN.
Authors: Nemsadze D. , Nemsadze G. , Tkeshelashvili V. , Tananashvi D.
Published: November 2023

Several studies have shown that the different biological subtypes of breast cancer are associated with variations in
treatment response and disease-specific outcomes. Treatment of breast cancer patients is based on several factors
including tumor morphology and expression of ER, PR and HER2/neu. Therefore, the aim of our investigation was to
evaluate the prevalence of the BC molecular subtypes, its 5-year survival and recurrence rates in Georgia. Methods:
This is a retrospective and descriptive study of 1985 patients with a confirmed diagnosis of BC referred in the “Institute
st st of Clinical Oncology” and treated there from January 1 2012 to December 31 2022. All statistical analyses were
performed using SPSS ver. 22.0 (SPSS,Chicago,IL).The data were reported as frequencies for histological type,tumors
grade,breast cancer subtypes and as means for patient's age at presentation.Categorical variables were analyzed using
the chi-squared test in univariate analysis. P-value<0.05 was considered to be statistically significant. Oncologic
outcomes were assessed using Kaplan–Meier analysis to identify factors affecting local recurrence,distant metastasis,
or death. A P value<0.05 was considered. Results: The most prevalent subtypes in patients with BC were Luminal A
(36.0%) and Luminal B (41.8%).The distribution of molecular subtypes is different than reported in developed countries
asian and african regions .This study is based on the data of a single clinic and it is impossible to provide nation-wide
programs for patients with BC for gene expression profiling.Therefore,IHC expression of ER,PR,and HER2 was carried
out in the frames of some municipal programs and self-financing mode. Therefore in 9.2% we got unknown subtype
patients with BC.