bluuebunny/crossref_metadata_2025 huggingface dataset:
Endovascular coil embolization of a spinal epidural arteriovenous fistula with associated cord compression from an enlarging venous varix
Authors: Ding Dale , Starke Robert M , Manka David , Crowley R Webster , Liu Kenneth C
Published: October 2015

Spinal arteriovenous fistulas (AVFs) completely isolated to the epidural compartment are exceedingly rare. As such, the optimal management of these lesions is poorly defined. The aim of this technical note is to describe our endovascular technique for the occlusion of a purely epidural AVF of the thoracic spine associated with cord compression from an associated enlarging venous varix. A 40-year-old male presented with severe right-sided back pain and anterior thigh numbness after a sports-related back injury six months previously. Spinal magnetic resonance imaging (MRI) showed an enhancing, extradural mass lesion at T12. Spinal angiography revealed an epidural AVF supplied by a radicular branch of the right T12 subcostal artery and draining into the paravertebral lumbar veins, as well as an adjacent 20 × 13 mm2 contrast-filling sac, compatible with a dilated venous varix. There was no evidence of intradural venous drainage. We elected to proceed with endovascular treatment of the lesion. At the time of embolization five days later, the venous varix had enlarged to 26 × 16 mm2. The T12 epidural AVF was completely occluded with two coils, without residual or recurrent AVF on follow-up angiography one month later. The patient made a full recovery, and complete resolution of the venous varix and cord compression were noted on MRI at three months follow-up. Endovascular coil embolization can be successfully employed for the treatment of appropriately selected spinal epidural AVFs. Cord compression from an enlarging venous varix can be treated concurrently with endovascular occlusion of an associated spinal epidural AVF.
‘I make the rules on my Wall’: Privacy and identity management practices on Facebook
Authors: Georgalou Mariza
Published: October 2015

Much significant work on the topic of privacy and identity on social network sites (SNSs) stems from the realms of media, information and cultural studies, and sociology eschewing language-based disciplines almost entirely. To redress the balance, this article draws on discourse-centred online ethnography, an approach which blends online ethnography with discourse analysis, to explore how self-presentation on Facebook is regulated by means of privacy. To this end, I analyse a dataset of statuses, comments, links, photographs and interviews from five Greek users. The findings highlight users’ creativity and criticality in combining software affordances with linguistic signals and textual practices to manage their privacy and hence their identity.
Blistering skin conditions
Authors: Gupta Vibhuti
Published: October 2015

Skin conditions are commonly encountered in primary care; they make up 15% of all consultations. The clinical presentations of blistering conditions are often similar, and therefore, it is important to make an accurate diagnosis. The purpose of this article is to provide an overview of common infective, non-immune and auto-immune causes of blistering skin disease.
Implementation of a Lactation Support Program in a Primary Care Pediatric Practice
Authors: Mueller Kathleen
Published: October 2015

Background and Objective. Breastfeeding has been shown to have an overall impact on the health and well-being of mothers and infants. Statistically, national and state breastfeeding rates are below the Healthy People 2020 target goals. A review of literature concluded that lactation support increased the overall rates of breastfeeding throughout the first year of life. The objectives of this quality improvement project were to increase the rates of breastfeeding at 2 weeks and 2 months of age by providing lactation support to the mother–infant dyad, to provide education for health care providers on the evidence-based recommendation for lactation support, and implement the program as standard of care. Methods. The quality improvement project used a retrospective chart review method to collect data. Data collection was done on the provision of lactation support for infants with the ICD-9 code of newborn feeding issues (779.31). Feeding methods were documented at 2 weeks and 2 months of age. Data were collected with regard to the numbers of referrals made before and after healthcare provider education. Results. Lactation support yielded higher rates of breastfeeding duration and exclusivity at 2 months of age yet referral rates demonstrated no significant difference. Conclusions and Implications. Research has shown that lactation support in the early postpartum period can increase breastfeeding rates throughout the first year of life. The lactation support program is standard of care for those newborns that meet evidence-based criteria, including excessive weight loss, inadequate stool output, and difficulty with breastfeeding with an ICD-9 code of newborn feeding issues (779.31).
A case report on 1-year follow-up of bilateral thalamic glioma
Authors: Ganewatte Eranga , Al-Zahrani Yahea , Purohit Bela , Kollias Spyros
Published: October 2015

Bilateral thalamic glioma is one of the rarest tumor occurrences, representing a small fraction of thalamic gliomas, which only accounts for 1–1.5% of all brain tumors. It is usually a diffuse, low-grade astrocytoma (WHO grade II), seen mainly in adults, with approximately 25% of them involving children under the age of 15. Radiotherapy is the main mode of treatment since surgical intervention is limited to a role of biopsy and management of secondary effects, due to the deep brain location of the lesion and the complexity of the involved structures. We report a 1-year follow-up of a 55-year-old female patient with bilateral WHO grade II thalamic astrocytoma. Following histological and neuroradiological consensus regarding the diagnosis, the patient was referred for radiotherapy. The effectiveness of available therapy and long-term neuroradiological follow-up is not reliably established due to rapid fatal evolution following diagnosis. Contrary to the norm, our patient showed stable disease with radiotherapy for a 1-year period.
Prodrugs of herpes simplex thymidine kinase inhibitors
Authors: Yanachkova Milka , Xu Wei-Chu , Dvoskin Sofya , Dix Edward J , Yanachkov Ivan B , Focher Federico , Savi Lida , Sanchez M Dulfary , Foster Timothy P , Wright George E
Published: October 2015

Background

Because guanine-based herpes simplex virus thymidine kinase inhibitors are not orally available, we synthesized various 6-deoxy prodrugs of these compounds and evaluated them with regard to solubility in water, oral bioavailability, and efficacy to prevent herpes simplex virus-1 reactivation from latency in a mouse model.

Methods

Organic synthesis was used to prepare compounds, High Performance Liquid Chromatography (HPLC) to analyze hydrolytic conversion, Mass Spectrometry (MS) to measure oral bioavailability, and mouse latent infection and induced reactivation to evaluate the efficacy of a specific prodrug.

Results

Aqueous solubilities of prodrugs were improved, oxidation of prodrugs by animal cytosols occurred in vitro, and oral absorption of the optimal prodrug sacrovir™ (6-deoxy- mCF3PG) in the presence of the aqueous adjuvant Soluplus® and conversion to active compound N2-[3-(trifluoromethyl)pheny])guanine ( mCF3PG) were accomplished in mice. Treatment of herpes simplex virus-1 latent mice with sacrovir™ in 1% Soluplus in drinking water significantly suppressed herpes simplex virus-1 reactivation and viral genomic replication.

Conclusions

Ad libitum oral delivery of sacrovir™ was effective in suppressing herpes simplex virus-1 reactivation in ocularly infected latent mice as measured by the numbers of mice shedding infectious virus at the ocular surface, numbers of trigeminal ganglia positive for infectious virus, number of corneas that had detectable infectious virus, and herpes simplex virus-1 genome copy numbers in trigeminal ganglia following reactivation. These results demonstrate the statistically significant effect of the prodrug on suppressing herpes simplex virus-1 reactivation in vivo.
Get strategic
Authors: Pitsis Tyrone S
Published: October 2015

With this essay I seek to elicit discussion and debate about some key ideas that I believe accentuates the differences between what academics do and what people do ‘in practice’, and yet also provides an opportunity for shared sense-making in order to bridge the scholar-practice divide. In particular I look at the differences in how we in academia approach theory and value compared to people in other domains. What I say here is not new or novel, but it has been absent from discussions between scholars and practitioners in our field of strategic contracting and negotiations. I close by arguing for closer collaboration between university, government, industry and the third sector in working on complex wicked problems facing societies and economies.
Congenital Erythropoietic Porphyria With Calcific Constrictive Pericarditis
Authors: Chowdhury Ujjwal K. , Patel Kartik , Seth Sandeep , Ray Ruma , Jagia Priya , Sahu Manoj
Published: October 2015

An 18-year-old boy with congenital erythropoietic porphyria and calcific constrictive pericarditis underwent total pericardiectomy. The cause of pericardial calcification could be deposition of porphyrins in the pericardium. Surgical importance of this rare condition is highlighted.
Right Coronary Artery to Pulmonary Arterial Fistula Associated With Tetralogy of Fallot
Authors: Chowdhury Ujjwal K. , Patel Kartik , Gupta Saurabh Kumar , Jagia Priya , Singh Sarvesh Pal
Published: October 2015

A 16-year-old boy with tetralogy of Fallot (TOF), pulmonary stenosis, and coronary artery to pulmonary arterial fistulous communication arising from the proximal right coronary artery is reported for its rarity. The surgical importance of this anomaly is highlighted. The diagnosis should be borne in cases of TOF, with echocardiographic demonstration of severe right ventricular outflow tract obstruction without a corresponding degree of systemic arterial desaturation.
Utilizing the PCICS Nursing Guidelines in Managing the CICU Patient
Authors: Justice Lindsey , Ellis Misty , St George-Hyslop Cecilia , Donnellan Amy , Trauth Amiee , Drouillard Brenda , Watt Claire , Callow Louise
Published: October 2015

The Pediatric Cardiac Intensive Care Society (PCICS) Nursing Guidelines were developed to provide an evidence-based resource for bedside cardiac intensive care unit nursing care. Guideline topics include postoperative care, hemodynamic monitoring, arrhythmia management, and nutrition. These evidence-based care guidelines were presented at the 10th International Meeting of PCICS and have been utilized in the preparation of this article. They can be accessed at http://www.pcics.org/resources/pediatric-neonatal/ . Utilization of these guidelines in practice is illustrated for single ventricle stage 1 palliation, Fontan operation, truncus arteriosus, and atrioventricular septal defect.
Unplanned Readmission to the Pediatric Cardiac Intensive Care Unit
Authors: Brunetti Marissa A. , Glatz Andrew C. , McCardle Ken , Mott Antonio R. , Ravishankar Chitra , Gaynor J. William
Published: October 2015

Background:

Factors leading to cardiac intensive care unit (CICU) readmission and the impact on mortality have yet to be well delineated. We sought to define the prevalence and outcome for unscheduled CICU readmission. Secondary objectives were to identify indications and risk factors for unscheduled CICU readmission.

Methods:

Retrospective analysis of prospectively collected registry data at a tertiary care children’s hospital. Pediatric and adult patients with congenital and acquired heart disease who survived to initial CICU discharge were included. Patients with unexpected return to the CICU for acute change in clinical status were defined as unscheduled readmissions.

Results:

Of the 645 discharges that met inclusion criteria, 37 resulted in unplanned readmission to the CICU. Patients requiring unscheduled readmission had higher mortality rates (16.2% vs 0.5%, P < .0001). Cardiac symptoms were the most common reason for readmission. On multivariate analysis, genetic anomaly ( P = .001) and longer length of stay (LOS) during the index CICU admission ( P = .01) were independently associated with readmission. For surgical patients, genetic anomaly ( P = .001), single-ventricle anatomy ( P = .05), and longer surgical support time ( P < .001) were independently associated with readmission.

Conclusion:

Unscheduled readmission to the CICU within the same hospitalization was uncommon but associated with a higher mortality rate. Genetic anomaly and longer initial LOS were important risk factors for the entire cohort. Single-ventricle anatomy and longer intraoperative course were risk factors for surgical readmissions.
Confessions of PCICU Leaders
Authors: da Cruz Eduardo M. , Tabbutt Sarah , Eisenhaur Mary C. , Jacobs Jeffrey P. , Graham Eric M. , Smith Liz C. , Simsic Janet , Laussen Peter C.
Published: October 2015

Background:

The pediatric cardiac intensive care environment is challenging and unpredictable due to the heterogeneous patient population. Leadership within this complex environment is critical for optimal outcomes.

Methods:

The 10th International Meeting of the Pediatric Cardiac Intensive Care Society provided a forum for leaders to share their own practice and experience that concluded with take-home messages regarding quality, safety, clinical effectiveness, stewardship, and leadership.

Results:

Presentations defined vital aspects for successful outcomes and highlighted ongoing challenges.

Conclusions:

Accomplishing exceptional outcomes requires a blend of clinical expertise, leadership, communication skills with briefing and debriefing, meaningful use of data, and transparency among peers and toward patients and their families.
Anomalous Origins of Coronary Arteries From the Pulmonary Artery
Authors: Karimi Mohsen , Kirshbom Paul M.
Published: October 2015

Anomalous origins of coronary arteries from the pulmonary artery are rare malformations in which the coronary arteries originate from pulmonary artery sinuses or branches. The consequences are variable although, in most cases, these anomalies lead to severe coronary hypoperfusion and ventricular dysfunction. Surgical correction is indicated once the diagnosis is established due to high early mortality associated with the disease. In nearly all cases, the anomalous artery can be excised from its pulmonary origin, mobilized, and reimplanted directly into the ascending aorta using different surgical techniques. In rare circumstances, technical modifications must be used to restore a normal dual coronary perfusion. The emphasis of this article is to provide a collective review of surgical options published in the literature.
Variability of Pulmonary Regurgitation in Proportion to Pulmonary Vascular Resistance in a Porcine Model of Total Resection of the Pulmonary Valve
Authors: Ko Yoshihiro , Morita Kiyozo , Abe Takayuki , Nakao Mitsutaka , Hashimoto Kazuhiro
Published: October 2015

Introduction:

Pulmonary regurgitation (PR) is a major concern after right ventricular (RV) outflow tract surgery. We assessed the impact of physiological changes in pulmonary vasculature on hemodynamic severity of PR and RV function and their potential clinical implications for postoperative management using a porcine model with severe PR.

Materials and Methods:

Eight porcine models of acute PR were established by means of resection of pulmonary valve on cardiopulmonary bypass. After separation from bypass and stabilization, blood flow in the main pulmonary artery was measured by a pulsed Doppler flowmeter, and RV systolic function was assessed on the basis of RV segment shortening (RVSS), which was analyzed by sonomicrometry. In the acute PR model, we verified the impact of pulmonary vascular resistance (Rp) on pulmonary regurgitant fraction (PRF) and RV function. Pulmonary vascular resistance was changed by manipulating the level of PaCo2 and by inhalation of nitric oxide (NO).

Results:

After bypass, the mean PRF was 40% ± 5%, and there was a deterioration of RV function. Under each ventilation condition (high Co2, low Co2, and NO 20 ppm), Rp was 836 ± 207 dyne × s × cm−5, 499 ± 125 dyne × s × cm−5, and 340 ± 102 dyne × s × cm−5, respectively, and PRF was 60% ± 10%, 37% ± 5%, and 24% ± 4%, respectively, under each condition. They also showed a positive correlation in all animals. Cardiac output and RVSS were decreased by hypercapnia, while they were significantly improved after NO inhalation.

Conclusions:

This study indicates that low Rp after right ventricular outflow tract reconstruction (RVOTR) resulting in acute PR is advantageous in reducing the severity of PR and RV volume load. These findings may have clinical implications for early and long-term postoperative management of patients subjected to RVOTR with resulting pulmonary valve incompetence.
Immunologic and Infectious Diseases in Pediatric Cardiac Critical Care
Authors: Axelrod David M. , Alten Jeffrey A. , Berger John T. , Hall Mark W. , Thiagarajan Ravi , Bronicki Ronald A.
Published: October 2015

Since the inception of the Pediatric Cardiac Intensive Care Society (PCICS) in 2003, remarkable advances in the care of children with critical cardiac disease have been developed. Specialized surgical approaches, anesthesiology practices, and intensive care management have all contributed to improved outcomes. However, significant morbidity often results from immunologic or infectious disease in the perioperative period or during a medical intensive care unit admission. The immunologic or infectious illness may lead to fever, which requires the attention and resources of the cardiac intensivist. Frequently, cardiopulmonary bypass leads to an inflammatory state that may present hemodynamic challenges or complicate postoperative care. However, inflammation unchecked by a compensatory anti-inflammatory response may also contribute to the development of capillary leak and lead to a complicated intensive care unit course. Any patient admitted to the intensive care unit is at risk for a hospital acquired infection, and no patients are at greater risk than the child treated with mechanical circulatory support. In summary, the prevention, diagnosis, and management of immunologic and infectious diseases in the pediatric cardiac intensive care unit is of paramount importance for the clinician. This review from the tenth PCICS International Conference will summarize the current knowledge in this important aspect of our field.
Early Perioperative Management After Pediatric Cardiac Surgery
Authors: Bastero Patricia , DiNardo James A. , Pratap J. Nick , Schwartz Jamie M. , Sivarajan V. Ben
Published: October 2015

The sessions of the symposium held in December 2014 allow us to capitalize on the shared knowledge and experience that arise from both cardiac anesthesia and cardiac intensive care. During this session, topics that crossed traditional boundaries of pediatric cardiac intensive care and pediatric cardiac anesthesia were presented and discussed. This article summarizes the five topics presented at the symposium.
Development of the Japan Science and Technology Agency Index of Competence to Assess Functional Capacity in Older Adults
Authors: Iwasa Hajime , Masui Yukie , Inagaki Hiroki , Yoshida Yuko , Shimada Hiroyuki , Otsuka Rika , Kikuchi Kazunori , Nonaka Kumiko , Yoshida Hiroto , Yoshida Hideyo , Suzuki Takao
Published: October 2015

Improvement in the health of older people and changes in their lifestyles necessitate a scale that can better measure their competence at a higher level. This study describes the development process of the Japan Science and Technology Agency Index of Competence (JST-IC) by (a) refining conceptual definitions and developing preliminary items and (b) examining the basic properties of the items. Participants were 1,253 septuagenarians (539 men and 714 women) living in communities, who were asked to judge whether they were independent via 88 items. To examine the basic properties of the preliminary items, five different analyses were conducted. Thirty-four items were considered as inappropriate (6 overlapped between the analyses): (a) 9 due to very high or low ratios of responders who answered “yes,” (b) 4 due to gender or regional differences, (c) 5 due to their weak association with health status, (d) 9 due to low communalities in factor analysis, and (e) 13 due to redundancy of meaning with other items. Conceptual definitions and preliminary items were developed, and the basic properties of the items were examined to create the JST-IC. The next step would be to screen the remaining 54 items to create the final version of the scale.
Takotsubo
Authors: Mumbert Kelly , Marschner Rebekka
Published: October 2015

Takotsubo cardiomyopathy (often referred to as broken heart syndrome) typically presents as apical ballooning, chest pain, shortness of breath, abnormal cardiac enzymes, and electrocardiogram changes. Although takotsubo cardiomyopathy mimics symptoms of an acute coronary event, in most cases it is a reversible cardiomyopathy with no long-term effects. Echocardiography is the noninvasive test of choice for initial presentation and follow-up of this syndrome. A case of takotsubo cardiomyopathy is presented and its clinical signs, echocardiographic features, and management discussed.
B-cell non-Hodgkin lymphoma linked to Coxiella burnetii
Authors: Melenotte Cléa , Million Matthieu , Audoly Gilles , Gorse Audrey , Dutronc Hervé , Roland Gauthier , Dekel Michal , Moreno Asuncion , Cammilleri Serge , Carrieri Maria Patrizia , Protopopescu Camelia , Ruminy Philippe , Lepidi Hubert , Nadel Bertrand , Mege Jean-Louis , Xerri Luc , Raoult Didier
Published: October 2015

Key Points

Coxiella burnetii is associated with an increased risk of lymphoma; its presence in the tumor microenvironment may favor lymphomagenesis. Lymphoma has to be considered in patients with Q fever and lymphoid disorders, especially those with persistent focalized infections.
Report of the European Respiratory Society/European Cystic Fibrosis Society task force on the care of adults with cystic fibrosis
Authors: Elborn J. Stuart , Bell Scott C. , Madge Susan L. , Burgel Pierre-Regis , Castellani Carlo , Conway Steven , De Rijcke Karleen , Dembski Birgit , Drevinek Pavel , Heijerman Harry G.M. , Innes J. Alistair , Lindblad Anders , Marshall Bruce , Olesen Hanne V. , Reimann Andreas L. , Solé Ampara , Viviani Laura , Wagner Thomas O.F. , Welte Tobias , Blasi Francesco
Published: October 2015

The improved survival in people with cystic fibrosis has led to an increasing number of patients reaching adulthood. This trend is likely to be maintained over the next decades, suggesting a need to increase the number of centres with expertise in the management of adult patients with cystic fibrosis. These centres should be capable of delivering multidisciplinary care addressing the complexity of the disease, in addition to addressing the psychological burden on patients and their families. Further issues that require attention are organ transplantation and end of life management.

Lung disease in adults with cystic fibrosis drives most of the clinical care requirements, and major life-threatening complications, such as respiratory infection, respiratory failure, pneumothorax and haemoptysis, and the management of lung transplantation require expertise from trained respiratory physicians. The taskforce therefore strongly reccommends that medical leadership in multidisciplinary adult teams should be attributed to a respiratory physician adequately trained in cystic fibrosis management.

The task force suggests the implementation of a core curriculum for trainees in adult respiratory medicine and the selection and accreditation of training centres that deliver postgraduate training to the standards of the HERMES programme.
The serotonin-lir nervous system of the Bryozoa (Lophotrochozoa): a general pattern in the Gymnolaemata and implications for lophophore evolution of the phylum
Authors: Schwaha Thomas F. , Wanninger Andreas
Published: October 2015

Background

Serotonin represents an evolutionary ancient neurotransmitter that is ubiquitously found among animals including the lophotrochozoan phylum Bryozoa, a group of colonial filter-feeders. Comparatively little is known on their nervous system, and data on their serotonin-lir nervous system currently are mostly limited to the basal phylactolaemates. Previous investigations indicated a common ground-pattern of the serotonin-lir nervous system in these animals, but in order to assess this on a larger scale, 21 gymnolaemate species from 21 genera were comparatively analysed herein.

Methods

Twenty-one species from 21 gymnolaemate genera were analysed by immunocytochemical stainings and confocal laser scanning microscopy.

Results

In all species the serotonin-lir signal is concentrated in the cerebral ganglion from where a nerve tract emanates laterally and traverses orally to engulf the foregut. Serotonin-lir perikarya are situated at the base of the tentacles that almost always correspond to the number of tentacles minus two. The oral side in almost all species shows three serotonin-lir perikarya followed by a ‘serotonergic gap’ that to our knowledge is not reflected in the morphology of the nervous system. Some species show additional serotonin-lir signal in tentacle nerves, visceral innervation and pore complexes.Paludicella articulatais exceptional as it shows signal in the latero-visceral nerves with serotonin-lir perikarya in the esophagus, parts of the tentacle sheath nerves as well as the frontal body wall around the parietal muscle bundles.

Conclusions

In general, the serotonin-lir nervous system in the Bryozoa shows a consistent pattern among its different clades with few deviations. Preliminary data on phylactolaemates suggest the presence of a ‘serotonergic gap’ similar to gymnolaemates. Both show a subset of oral tentacles and the remaining tentacles in gymnolaemates which correspond to the lateral tentacles of phylactolaemates. The lophophoral concavity lacks serotonin-lir perikarya indicating that due to their larger sizes and increased tentacle number, the horse-shoe shaped arrangement could represent an apomorphy of phylactolaemates.
Complete genome sequence of Mycobacterium tuberculosis K from a Korean high school outbreak, belonging to the Beijing family
Authors: Han Seung Jung , Song Taeksun , Cho Yong-Joon , Kim Jong-Seok , Choi Soo Young , Bang Hye-Eun , Chun Jongsik , Bai Gill-Han , Cho Sang-Nae , Shin Sung Jae
Published: October 2015

Mycobacterium tuberculosis K, a member of the Beijing family, was first identified in 1999 as the most prevalent genotype in South Korea among clinical isolates of M. tuberculosis from high school outbreaks. M. tuberculosis K is an aerobic, non-motile, Gram-positive, and non-spore-forming rod-shaped bacillus. A transmission electron microscopy analysis displayed an abundance of lipid bodies in the cytosol. The genome of the M. tuberculosis K strain was sequenced using two independent sequencing methods (Sanger and Illumina). Here, we present the genomic features of the 4,385,518-bp-long complete genome sequence of M. tuberculosis K (one chromosome, no plasmid, and 65.59 % G + C content) and its annotation, which consists of 4194 genes (3447 genes with predicted functions), 48 RNA genes (3 rRNA and 45 tRNA) and 261 genes with peptide signals.
Estrogen Receptor-Selective Agonists Modulate Learning in Female Rats in a Dose- and Task-Specific Manner
Authors: Pisani Samantha L. , Neese Steven L. , Katzenellenbogen John A. , Schantz Susan L. , Korol Donna L.
Published: October 2015

Estrogens are well known for their enhancing effects on hippocampus-sensitive cognition. However, estrogens can also impair learning and memory, particularly the acquisition of striatum-sensitive tasks. These cognitive shifts appear to be mediated through local estrogen receptor (ER) activation in each neural structure, but little information is known regarding which specific ER subtypes drive the opposing effects on learning. Elucidating the mnemonic roles of discrete ER subtypes is essential for predicting how treatments with distinct ER pharmacology such as drugs, hormone therapies, and phytoestrogen supplements affect cognitive abilities in and thus the daily lives of the women who take them. The present study examined the effects of the ERα-selective compound propyl pyrazole triol and the ERβ-selective compounds diarylpropionitrile and Br-ERb-041 on place and response learning in young adult female rats. Long-Evans rats were ovariectomized and maintained on phytoestrogen-free chow for 3 weeks before behavioral training, with treatments administered via subcutaneous injection 48 and 24 hours before testing. A dose-response paradigm was used, with each compound tested at 4 different doses in separate groups of rats. Propyl pyrazole triol, diarylpropionitrile, and Br-ERb-041 all enhanced place learning and impaired response learning, albeit with distinct dose-response patterns for each compound and task. These results are consistent with the detection of ERα and ERβ in the hippocampus and striatum and suggest that learning is modulated via activation of either ER subtype.
Cardiomyocyte and Vascular Smooth Muscle-Independent 11β-Hydroxysteroid Dehydrogenase 1 Amplifies Infarct Expansion, Hypertrophy, and the Development of Heart Failure After Myocardial Infarction in Male Mice
Authors: White Christopher I. , Jansen Maurits A. , McGregor Kieran , Mylonas Katie J. , Richardson Rachel V. , Thomson Adrian , Moran Carmel M. , Seckl Jonathan R. , Walker Brian R. , Chapman Karen E. , Gray Gillian A.
Published: October 2015

Global deficiency of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), an enzyme that regenerates glucocorticoids within cells, promotes angiogenesis, and reduces acute infarct expansion after myocardial infarction (MI), suggesting that 11β-HSD1 activity has an adverse influence on wound healing in the heart after MI. The present study investigated whether 11β-HSD1 deficiency could prevent the development of heart failure after MI and examined whether 11β-HSD1 deficiency in cardiomyocytes and vascular smooth muscle cells confers this protection. Male mice with global deficiency in 11β-HSD1, or with Hsd11b1 disruption in cardiac and vascular smooth muscle (via SM22α-Cre recombinase), underwent coronary artery ligation for induction of MI. Acute injury was equivalent in all groups. However, by 8 weeks after induction of MI, relative to C57Bl/6 wild type, globally 11β-HSD1-deficient mice had reduced infarct size (34.7 ± 2.1% left ventricle [LV] vs 44.0 ± 3.3% LV, P = .02), improved function (ejection fraction, 33.5 ± 2.5% vs 24.7 ± 2.5%, P = .03) and reduced ventricular dilation (LV end-diastolic volume, 0.17 ± 0.01 vs 0.21 ± 0.01 mL, P = .01). This was accompanied by a reduction in hypertrophy, pulmonary edema, and in the expression of genes encoding atrial natriuretic peptide and β-myosin heavy chain. None of these outcomes, nor promotion of periinfarct angiogenesis during infarct repair, were recapitulated when 11β-HSD1 deficiency was restricted to cardiac and vascular smooth muscle. 11β-HSD1 expressed in cells other than cardiomyocytes or vascular smooth muscle limits angiogenesis and promotes infarct expansion with adverse ventricular remodeling after MI. Early pharmacological inhibition of 11β-HSD1 may offer a new therapeutic approach to prevent heart failure associated with ischemic heart disease.
Hyperneoliberalism: Youth, Labor, and Militant Mice in Japan
Authors: Driscoll Mark
Published: October 2015

Japan has gone from being the paradigmatic developmental state in the 1960s and 1970s to being a representative neoliberal state today. This dramatic ideological and political-economic transformation has come so suddenly that it qualifies as a kind of “hyperneoliberalism.” Whereas in the 1970s and 1980s Japan's labor market was characterized by life-time employment and generous benefits—producing the seemingly ubiquitous subjectivity of the “salaryman”—today the sociology of labor in Japan seems to be overwhelmed by the precarious labor subjectivities of the freeters and NEETS (not in education, employment, or training). Beginning in the mid-1990s, Japanese capitalists in alliance with the Liberal Democratic Party have deliberately restructured Japanese labor as one solution to the purported profit squeeze. This has had the effect of doubling the poverty rate in Japan in twenty years and producing, seemingly overnight, huge disparities in wealth and income. One positive effect of this emergence of hyperneoliberalism has been the simultaneous appearance of a new leftist culture and politics to contest hyperneoliberalism ideologically and politically. This essay discusses three of the main figures in this new activist left—Hirai Gen, Matsumoto Hajime, and Amamiya Karin—and demonstrates some of the ways that their work and activism are sketching out an exciting new future beyond capitalism itself.
Mechanism of the Formation of Hierarchical-structured Bismuth Tungstate Photocatalyst Particles through Counter-flow Supply of Bismuth and Tungsten Sources
Authors: Hori Haruna , Takase Mai , Amano Fumiaki , Ohtani Bunsho
Published: October 2015

The mechanism of formation of hierarchical “flake-ball”-structured bismuth tungstate (BTO) particles was studied on the basis of structural analyses and was revealed to be the growth of plate-like BTO crystallites on the tungsten oxide/BTO-modified surface of bismuth hydroxide particles by supplying tungsten and bismuth from the outside and inside of the core particles, respectively.
Codeposition of Colloidal Platinum Particles and Iron Chloride Precursor on TiO2 for Efficient Catalytic Oxidation of CO to CO2
Authors: Einaga Hisahiro , Shiranita Ryo , Saito Hikaru , Hata Satoshi
Published: October 2015

Codeposition of metal chlorides with Pt colloidal nanoparticles on TiO2 followed by oxidation at 400 °C and reduction at 200 °C improved the activity for Pt-catalyzed CO oxidation with stoichiometric amount of O2. The highest activity was obtained when FeCl3 was used as the additive with the Fe/Pt ratio of 0.2. XAFS, X-EDS, FTIR, and catalytic studies revealed that the deposition of Fe species on the reduced Pt sites gave active sites, which exhibited CO oxidation with high efficiency.
A Gift from Kyriakos Delopoulos to the Library of the Benaki Museum: 292 Books with Autograph Dedications by the Authors
Authors: Πανταζοπούλου Τόνια , Τσάκωνα Πίτσα
Published: October 2015

Δεν παρατίθεται περίληψη.
The Dimitris Davis Archive in the Benaki Museum
Authors: Αλεξάκη Ευγενία , Παπαχρίστου Κωνσταντίνος Α. , Πολυχρονιάδου Ελίζα
Published: October 2015

Δεν παρατίθεται περίληψη.
Byzantium 330-1453: an important exhibition abroad
Authors: Γερουλάνου Αιμιλία
Published: October 2015

Δεν παρατίθεται περίληψη.
Ατομικές χορηγήσεις της Ρωμαϊκής Πολιτείας (civitas romana) και η διάδοση της στη Ρωμαϊκή επαρχία Μακεδονία: ΙΙ. η περίπτωση της Βέροιας, έδρα του Κοινού των Μακεδόνων
Authors: Σαμσάρης Δημήτρης Κ.
Published: October 2015

No Abstract
Oppidum celetrum: ο Λιμναίος οικισμός του Δισπηλιού Καστοριάς
Authors: Μουτσόπουλος Ν. Κ.
Published: October 2015

No Abstract
Δέκα έγγραφα των Ολυμπίων αγωνιστών Αναγνώστη και Μιχάλη Πιτσάβα
Authors: Σπανός Κώστας
Published: October 2015

No Abstract
Το πρωτάτο του Αγίου Αθανασίου: αναπαράσταση Ν. όψης
Authors: Φούντας Παντελής Γ.
Published: October 2015

No Abstract
Περιπέτεια του Αναστάσιου Δ. Καρατάσου στην Θεσσαλονίκη το 1873
Authors: Παπάγγελος Ιωακείμ Αθ.
Published: October 2015

No abstract
Τελετή προς τιμήν του οικουμενικού Πατριάρχη κ.κ. Βαρθολομαίου στην Εταιρεία Μακεδονικών Σπουδών: (1 Οκτωβρίου 1997)
Authors: Εταιρεία Μακεδονικών Σπουδών (ΕΜΣ)
Published: October 2015

No Abstract
Δραστηριότητες της Τράπεζας της Ανατολής στο Μοναστήρι, στα Σκόπια και στις Σέρρες, 1905-1911
Authors: Χεμίκογλου Ε. Α. , Καριζώνη Αικατερίνη
Published: October 2015

No Abstract
Μαρία Σιγανίδου
Authors: Παπαευθυμίου-Παπανθίμου Α. , Πιλάλη-Παπαστερίου Α.
Published: October 2015

No Abstract
Νέα ιστορικά στοιχεία για τον Αναστάσιο Εμ. Παπά
Authors: Βακαλόπουλος Αποστ. Ε.
Published: October 2015

No Abstract
Το Ελληνικό κράτος και ο σχολικός θεσμός στον υπόδουλο ελληνισμό: απόπειρα δημιουργίας νέου θεσμικού πλαισίου μέσα από τη νομιμοποίηση του θεσμού της σχολικής επιθεώρησης στη Μακεδονία το 1907
Authors: Ηλιάδου-Τάχου Σοφία
Published: October 2015

No abstract
Βυζαντινή Μακεδονία: ένα επιστημονικό συμπόσιο στην Μελβούρνη της Αυστραλίας
Authors: Καραθανάσης Αθ. Ε.
Published: October 2015

No abstract
Νικ. Α. Λούστα, Δημοδιδασκάλου, Η ιστορία του Νυμφαίου Νέβεσκας-Φλωρίνης
Authors: Καραθανάσης Αθ. Ε.
Published: October 2015

No abstract
Ετυμολογικά της περιοχής Πιερίας
Authors: Δούγα-Παπαδοπούλου Ευανθία
Published: October 2015

No abstract
Βιβλιογραφικό σχεδίασμα για την πόλη και την περιοχή Καστοριάς
Authors: Πελαγίδης Στάθης
Published: October 2015

No abstract
Ανασκαφή στον νεολιθικό οικισμό του Ζαγκλιβερίου νομού Θεσσαλονίκης
Authors: Γραμμένος Δ. Β. , Κώτσος Σ. , Σαμαρτζίδου Ελένη
Published: October 2015

No abstract
Παραλειπόμενα του Μακεδονικού Αγώνα από το αρχείο Παύλου & Ναταλίας Μελά
Authors: Ακτσόγλου Ιάκωβος Ζ.
Published: October 2015

No abstract 
Συμπληρωματικές πληροφορίες για τον επίσκοπο Πολυανής Φώτιο Παγιώτα
Authors: Τσεκουνάρης Μιχαήλ Α.
Published: October 2015

No abstract 
Ο πληθυσμός της Θεσσαλονίκης και η Ελληνική κοινότητα της κατά το 1913
Authors: Δημητριάδης Βασίλης
Published: October 2015

No abstract 
Ένας άγνωστος οκταγωνικός ναός στη Θεσσαλονίκη
Authors: Μακρή Ευτέρπη
Published: October 2015

No abstract 
Λαξευτός τάφος Καλλιθέας Βεροίας
Authors: Τζαναβάρη Κατερίνα
Published: October 2015

No abstract 
Η κτητορική επιγραφή του ναού των Αγίων Αποστόλων Καστοριάς και ο ζωγράφος Ονούφριος
Authors: Γκολομπίας Γιώργος
Published: October 2015

No abstract 
Ποικίλα φιλολογικά
Authors: Μπουμπουλίδης Φαίδων Κ.
Published: October 2015

No abstract
Ανέκδοτη ελληνική επιγραφή των αυτοκρατορικών χρόνων από την Τερπνή Νιγρίτας
Authors: Σαμσάρης Δημήτρης Κ.
Published: October 2015

No abstract
Νέα στοιχεία για τη χρονολόγηση του "Χαλασμού" της Νάουσας και των μοναστηριών στα 1822
Authors: Χιονίδης Γιώργος Χ.
Published: October 2015

No abstract
Πολιτική, κοινωνική και οικονομική δομή του πασαλικιού Μοναστηριού στα μέσα του 19ου αιώνα
Authors: Βακαλόπουλος Κωνσταντίνος
Published: October 2015

No abstract
Nicolas Oikonomidès, Documents et études sur les institutions de Byzance (VIIe-XVe s.)
Authors: Θεοχαρίδης Γ. Ι.
Published: October 2015

No abstract
Μέγας Αλέξανδρος, 2300 χρόνια από τον θάνατο του
Authors: Τουρατσόγλου Γιάννης Π.
Published: October 2015

No abstract
Ένα υπόμνημα για την πυρκαγιά της Θεσσαλονίκης στα 1917 και την περίθαλψη των θυμάτων
Authors: Παπαστάθης Χαραλ. Κ.
Published: October 2015

No abstract
Παρατηρήσεις στην οικοδομική ιστορία και την οχύρωση της Μ. Διονυσίου Αγ. Όρους κατά το 16ο αιώνα
Authors: Θεοχαρίδης Πλούταρχος Λ.
Published: October 2015

No abstract
Γεωργίου Δημητροκάλλη, Οι δίκογχοι χριστιανικοί ναοί
Authors: Γούναρης Γ.
Published: October 2015

No abstract
Το Μακεδονικό Ζήτημα σε μια καινούργια "Ιστορία της Νεώτερης Ελλάδας"
Authors: Νοτάρης Ιωαν. Σωτ.
Published: October 2015

No abstract
Το ιστορικόν αρχείον της Ιεράς Μητροπόλεως Θεσσαλονίκης
Authors: Αγγελόπουλος Αθανάσιος
Published: October 2015

No abstract
Θεοχάρη Παζαρά, Η Ροτόντα του Αγίου Γεωργίου στη Θεσσαλονίκη
Authors: Πέτσας Φ. Μ.
Published: October 2015

No abstract
Η αγγλική μετάφραση της γραμματικής του Αθανασίου Χριστόπουλου
Authors: Καμαριανός Νέστωρ
Published: October 2015

No abstract
Ελληνο-σερβικό ιστορικό συμπόσιο Καβάλας (7-10 Νοεμβρίου 1976)
Authors: Παπανδριανός Ιωάννης Α.
Published: October 2015

No abstract
Τα σχολεία της ελληνικής παροικίας Βελιγραδίου και ο κανονισμός του Ελληνικού της Παρθεναγωγείου το 1870
Authors: Ανδρεάδης Χρήστος Γ.
Published: October 2015

No abstract
Τα Γενιτσά (Γιαννιτσά) το 1904 μέσα από την έκθεση του Γεωργίου Τσορμπατζόγλου
Authors: Τιμοθεάδης Τιμόθεος Ι.
Published: October 2015

No abstract
Η «ΜΟΡΦΗ» TOΥ ΚΑΠΕΤΑΝ ΜΠΑΣΔΕΚΗ
Authors: ΠΟΛΙΤΗΣ ΑΛΕΞΗΣ
Published: October 2015

Δεν παρατίθεται περίληψη.
ΕΘΝΙΚΗ ΣΥΝΕΙΔΗΣΗ ΚΑΙ ΔΗΜΟΣΙΑ ΧΡΗΣΗ ΤΗΣ ΙΣΤΟΡΙΑΣ ΣΤΗ ΣΥΓΧΡΟΝΗ ΓΕΡΜΑΝΙΑ. ΠΡΟΒΛΗΜΑΤΑ «ΥΠΕΡΒΑΣΗΣ ΤΟΥ ΠΑΡΕΛΘΟΝΤΟΣ»
Authors: ΛΟΥΛΟΣ Κ.
Published: October 2015

Δεν παρατίθεται περίληψη.
ΠΑΤΡΙΑΡΧΙΚΗ ΣΥΝΟΔΟΣ "ΠΕΡΙ ΚΑΘΑΙΡΕΣΕΩΣ ΤΩΝ ΦΙΛΟΣΟΦΙΚΩΝ ΜΑΘΗΜΑΤΩΝ" ΤΟΝ ΜΑΡΤΙΟ TOΥ 1821
Authors: ΛΑΠΠΑΣ ΚΩΣΤΑΣ
Published: October 2015

Δεν παρατίθεται περίληψη.
ΕΤΑΙΡΕΙΑ ΕΛΛΗΝΙΚΗΣ ΑΤΜΟΠΛΟΪΑΣ (1857 - 1869). ΥΠΟΘΕΣΕΙΣ ΕΡΕΥΝΑΣ ΚΑΙ ΠΡΟΒΛΗΜΑΤΙΚΗ
Authors: ΠΑΠΑΘΑΝΑΣΟΠΟΥΛΟΣ ΚΩΝΣΤΑΝΤΙΝΟΣ
Published: October 2015

Δεν παρατίθεται περίληψη.
ΤΑ ΕΛΛΗΝΙΚΑ ΣΥΝΤΑΓΜΑΤΑ ΚΑΙ Η ΙΔΙΟΤΗΤΑ ΤΟΥ ΠΟΛΙΤΗ (1844-1927). ΑΠΟΠΕΙΡΑ ΙΣΤΟΡΙΚΗΣ ΕΠΙΣΚΟΠΗΣΗΣ
Authors: ΚΟΚΚΙΝΟΣ ΓΙΩΡΓΟΣ
Published: October 2015

Δεν παρατίθεται περίληψη στα ελληνικά.
ΕΜΠΟΡΙΟ ΚΑΙ ΝΑΥΤΙΛΙΑ ΤΟΝ 19ο ΑΙΩΝΑ. ΤΟ ΕΠΙΧΕΙΡΗΜΑΤΙΚΟ ΔΙΚΤΥΟ ΤΩΝ ΕΛΛΗΝΩΝ ΤΗΣ ΔΙΑΣΠΟΡΑΣ. Η «ΧΙΩΤΙΚΗ» ΦΑΣΗ (1830-1860)
Authors: ΧΑΡΛΑΥΤΗ ΤΖΕΛΙΝΑ
Published: October 2015

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ΚΑΤΑΛΟΓΟΣ ΙΣΤΟΡΙΚΟΥ ΑΡΧΕΙΟΥ ΖΑΚΥΝΘΟΥ - Α
Authors: ΚΟΛΥΒΑ - ΚΑΡΑΛΕΚΑ ΜΑΡΙΑΝΝΑ
Published: October 2015

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ΘΕΜΕΛΙΩΣΗ ΚΑΙ ΑΥΤΟΣΥΝΕΙΔΗΣΙΑ ΤΗΣ ΕΠΙΣΤΗΜΗΣ ΤΗΣ ΙΣΤΟΡΙΑΣ
Authors: ΔΕΛΗΓΙΩΡΓΗ ΑΛΕΞΑΝΔΡΑ
Published: October 2015

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TABLE DES MATIÈRES
Authors: Mnimon Mnimon
Published: October 2015

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Η ΤΥΠΟΛΟΓΙΑ ΚΑΙ ΟΙ ΣΧΕΣΕΙΣ ΤΩΝ ΤΕΚΜΗΡΙΩΝ ΜΙΑΣ ΕΠΙΧΕΙΡΗΣΗΣ. Η ΣΕΙΡΑ "ΠΡΟΣΩΠΙΚΟ" TOΥ ΑΡΧΕΙΟΥ "Α.Κ.Ε. ΑΦΟΙ ΡΕΤΣΙΝΑ"
Authors: ΜΠΑΓΙΑΣ ΑΝΔΡΕΑΣ , ΠΑΠΑΣΤΕΦΑΝΑΚΗ ΛΗΔΑ
Published: October 2015

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Η ΒΥΖΑΝΤΙΝΗ ΟΙΚΟΓΕΝΕΙΑ ΚΑΙ ΤΑ ΠΡΟΒΛΗΜΑΤΑ ΤΗΣ
Authors: ΚΑΖΔΑΝ Α. Π.
Published: October 2015

Δεν παρατίθεται περίληψη.
ΙΣΤΟΡΙΚΟ ΑΡΧΕΙΟ ΜΑΚΕΔΟΝΙΑΣ. ΠΕΡΙΕΧΟΜΕΝΑ
Authors: ΠΑΠΠΑ ΑΜΑΛΙΑ
Published: October 2015

<span style="font-size: 10.0pt; font-family: Verdana; mso-fareast-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-ansi-language: EL; mso-fareast-language: EL; mso-bidi-language: AR-SA;">Δεν παρατίθεται περίληψη.     /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;}  
ΤΑ ΑΡΧΕΙΑ ΤΗΣ ΑΥΤΟΝΟΜΗΣ ΥΠΗΡΕΣΙΑΣ ΕΠΙΣΙΤΙΣΜΟΥ ΜΑΚΕΔΟΝΙΑΣ (Α.Υ.Ε.Μ.)
Authors: ΠΑΠΑΔΟΠΟΥΛΟΥ ΚΑΤΕΡΙΝΑ , ΚΑΛΑΝΤΖΗΣ ΓΙΩΡΓΟΣ
Published: October 2015

<span style="font-size: 10.0pt; font-family: Verdana; mso-fareast-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-ansi-language: EL; mso-fareast-language: EL; mso-bidi-language: AR-SA;">Δεν παρατίθεται περίληψη.     /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman"; mso-ansi-language:#0400; mso-fareast-language:#0400; mso-bidi-language:#0400;}  
Χριστίνα Κουλούρη, Ιστορία και Γεωγραφία στα ελληνικά σχολεία (1834-1914). Γνωστικό αντικείμενο και ιδεολογικές προεκτάσεις. Ανθολόγιο κειμένων. Βιβλιογραφία σχολικών εγχειριδίων, Αθήνα (Ιστορικό Αρχείο Ελληνικής Νεολαίας) 1988, 789 σελ.
Authors: ΠΟΛΙΤΗΣ ΑΛΕΞΗΣ
Published: October 2015

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Π. Ε. Πετράκης (μέ τη συνεργασία του Χ. Πανώριου), Τα σημεία καμπής στη δραστηριότητα της ελληνικής οικονομίας (1840-1913), Αθήνα, ΜΙΕΤ, 1992, 234 σ.
Authors: ΑΓΡΙΑΝΤΩΝΗ ΧΡΙΣΤΙΝΑ
Published: October 2015

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ΤΑ ΜΑΘΗΤΟΛΟΓΙΑ ΤΟΥ ΔΗΜΟΤΙΚΟΥ ΣΧΟΛΕΙΟΥ ΜΑΡΜΑΡΙΟΥ. ΜΙΑ ΠΡΩΤΗ ΕΠΕΞΕΡΓΑΣΙΑ ΓΙΑ ΤΗΝ ΠΕΡΙΟΔΟ 1900-1940
Authors: ΤΣΙΜΠΟΥΚΗ ΒΑΣΩ
Published: October 2015

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