bluuebunny/crossref_metadata_2025 huggingface dataset:
Terapias medicamentosas empregadas no tratamento da Covid-19 no Brasil: revisão bibliográfica narrativa
Authors: Braz Paulo Rodrigo Lima , Cardoso Maria Aurineide Barbosa da Silva , Oliveira Raphael Santos de , Silva Emanuela Aquino da , Sales Neto Manoel Ribeiro de , Linard Cybelle Façanha Barreto Medeiros , Lopes Nadja Mara de Sousa
Published: October 2021

Objetivo: Apresentar um panorama sobre a fisiopatologia da Covid-19 e tratamentos medicamentosos utilizados no Brasil. Metodologia: Trata-se de uma revisão bibliográfica narrativa. Foram realizadas buscas em sites oficiais (Ministério da Saúde do Brasil; Butantan); bases de dados Cochrane, Google Scholar, Pubmed e Scielo e textos complementares. As buscas ocorreram entre fevereiro e junho de 2021 com os termos ‘Covid-19’, ‘Coronavírus’ ‘Pandemia’, ‘Vacinas Covid-19’, ‘SARS-CoV-2’ e ‘Terapias medicamentosas Covid-19’. Foram inclusos textos em inglês, português e espanhol, publicados a partir de 2020 e excluídos textos que não se relacionavam à temática. Resultados: Azitromicina, corticosteroides, antirretrovirais e anticoagulantes exemplificam fármacos usados no tratamento de Covid-19, além de prevenção com vacinas. Conclusão: No período desta revisão notou-se o esforço da comunidade científica no reposicionamento de fármacos para tratar a doença, mas não foram encontradas evidências que comprovassem a efetividade de um tratamento específico. As vacinas tornam-se um grande aliado na prevenção da doença.
What is the impact of drug therapy with antiresorptive agents on the success of dental implants? a literature review
Authors: Gonçalves Gabriela Sumie Yaguinuma , Alves Leandro Marcel Soares , Marques Milena Steluti
Published: October 2021

Objective: To review the current literature and provide the latest information on anti-resorptive agent-induced osteonecrosis of the jaw (ARONJ), including our basic and clinical research findings, as well as discuss the risks of developing osteonecrosis in patients undergoing dental implant surgery in use of anti-resorptive drugs (ARDs). Methods: A literature review was performed using articles published in indexed journals based on Pubmed, Web of Science, Embase and Scopus databases. Results: Our results show that the placement of dental implants in patients treated with ARDs should be carefully evaluated, these patients are not free from complications and, therefore, the risk assessment should be done individually, as one of the most serious complications, although rare, is the ARONJ. Conclusion: Thus, all patients treated with this type of drug should be informed about the risk of implant loss or the possibility of osteonecrosis, being necessary to inform about the increased risk also patients who already have osteointegrated implants and will start therapy with bisphosphonates (BPT). And, in addition, establishing a relationship and collaboration between doctor, dentist and patient is essential for the good prognosis of these cases.
Análise da qualidade da água recreativa em balneários da Cidade de Açailândia, Maranhão, Brasil
Authors: Santos Carlos Alberto Andrade Serra dos , Oliveira Luciene de , Barbosa Mikaely Alencar , Horster Tania Regina Zanella , Nascimento Bruno Lucio Meneses , Serra Maria Aparecida Alves de Oliveira , Costa Ivo Almeida , Orlanda José Fábio França
Published: October 2021

Desde as primeiras civilizações o homem busca se instalar sempre próximo a margens de rios, lagos e mares buscando suprir desde as necessidades básicas até as mais complexas. Essa relação do homem com a natureza é um assunto muito discutido atualmente, pois, a utilização dos recursos hídricos tem gerado graves impactos aos ecossistemas, poluição, contaminação e podendo culminar na escassez desse bem natural. O presente estudo teve como finalidade avaliar a qualidade da água recreativa em balneários banhados pelo córrego Mosquito da cidade de Açailândia- MA conforme os padrões de estabelecidos pela Portaria nº 888 de 2021 do Ministério da Saúde (MS) as resoluções CONAMA nº 274/2000 e nº 357/2005. O levantamento inicial da área de estudo foi feito, utilizando georreferenciamento pela ferramenta exploratória Google Earth. O critério de escolha dos pontos amostrais se deu pelo motivo de serem os mais frequentados para atividade balneária recreativa no município. Foram realizados testes físico-químicos e microbiológicos pelas técnicas APHA, EPA, SM e FUNASA. De acordo com os resultados obtidos, a maioria dos parâmetros analisados em todos os pontos (P1, P2, P3 e P4), tais como como pH, índices de ferro, fósforo, nitrito e nitrato não se encontram em conformidade com a Portaria nº 888/2021 do MS além de altas concentrações de bactérias termotolerantes com concentração ≥1600 NMP/100 mL mostrando que possivelmente o corpo hídrico está poluído. Assim, a água em todos os pontos de coleta analisados não está apta para o contato primário tendo uma predominância de classe 3.
Curso clínico de mulheres grávidas com infecção pelo SARS-CoV-2 com desenvolvimento da COVID-19: revisão integrativa da literatura
Authors: Zoldan Camila , Pereira Jullya Hingred , Irias Maria Isabella Lima , Oliveira Natália Gonçalves de
Published: October 2021

A pandemia de SARS-CoV-2 acarreta impactos à saúde ainda desconhecidos e que são objetivos de estudos. Dentre esses, estão a forma como a COVID-19 se manifesta em gestantes e puérperas, quais os desfechos neonatais e qual o perfil epidemiológico dessas mulheres. Para tanto foi conduzida uma Revisão integrativa da literatura nas bases de dados PubMed. Os descritores utilizados para delimitar as buscas foram gravidez, SARS-CoV-2, COVID-19. Assim sendo, 27 artigos foram selecionados ao final das buscas. Sendo 92,6% deles publicados ano de 2020, com relação ao país de origem de realização dos estudos o mais prevalente com 8 (29,62%) artigos, foram os Estados Unidos. Evidências apontam que há relações entre maior necessidade de internação em Unidade de Terapia Intensiva e uso de suporte ventilatório entre gestantes com COVID-19. A gestação parece estar relacionada com formas severas da doença, porém, existem outros fatores influenciadores, como obesidade e diabetes mellitus. Houve maior proporção de gestantes negras e latinas entre as afetadas, com aparente aumento no risco de morte entre as latinas. Também, notou-se um aumento nos partos pré-termo quando da forma severa. Dessa forma, fica evidente que há uma relação entre a chance de agravamento da COVID-19 entre gestantes com SARS-CoV-2, em especial as sintomáticas e com comorbidades. Além disso, aumento da taxa de partos pré-termo com a forma severa. Assim, adotar medidas de prevenção e vacinação entre essa população se mostra como as principais formas de evitar agravamentos, partos pré-termo e óbitos.
Práticas de Integração Ensino-Serviço-Comunidade: a experiência do cuidado à saúde mental na estratégia saúde da família
Authors: Santos Bruna Lago , Nascimento Alana Clara Santana , Cunha Ana Paula de Souza , Brito Dornelio Arcanjo de , Mendes Flávio Gabriel Barbosa , Farias Neto José Santana , Reis Leonardo Victor Costa , Silva Junior Paulo Sérgio Almeida , Queiroz Stefanie Sousa de , Ximenes Thaís Pires de Melo
Published: October 2021

Objetivo: explanar as vivências de graduandos do segundo ano de medicina, relativas à implantação do projeto de intervenção em saúde mental em uma Unidade de Saúde da Família (USF) no município de Jequié, Bahia, Brasil. Metodologia: trata-se do relato de experiência, evidenciando a construção do projeto de intervenção da disciplina Práticas de Integração Ensino, Serviço e Comunidade e os resultados alcançados na USF. Foram realizados acompanhamentos das atividades: visitas domiciliares, palestras em sala de espera, Práticas Integrativas e Complementares, feira de saúde, e matriciamento; complementando o estudo, foi utilizada a ferramenta Self-Reporting Questionnaire (SRQ-20) e a capacitação dos profissionais de saúde para uso posterior da ferramenta na comunidade. Resultados: no contexto dos discentes, o vínculo com a comunidade possibilitou o conhecimento do cotidiano dos pacientes, em seu âmbito biopsicossocial, e contribuiu para a formação médica humanizada. Os profissionais demonstraram interesse na melhoria dos serviços oferecidos, embora houvesse uma resistência na operacionalização das atividades na rotina da unidade. A população que participou das atividades propostas avaliou-as de forma positiva, apesar da baixa adesão, limitando o alcance das intervenções. Conclusão: a experiência vivenciada mostrou-se benéfica para a consolidação de uma nova forma de cuidado à saúde mental dos pacientes da USF, consistindo na integração ensino-serviço-comunidade.
O cotidiano dos técnicos de enfermagem na Estratégia Saúde da Família
Authors: Júlio Vanessa Aparecida , Silva Joseane da , Amorim Maria Marta Amancio , Silva Juliana Ferreira da , Mendonça Edna Mara , Engela Maria Helena Trindade , Lanza Fernanda Moura
Published: October 2021

O objetivo do estudo é compreender o processo de trabalho dos técnicos de enfermagem que atuam nas equipes da Estratégia Saúde da Família. O estudo de caso é de abordagem qualitativa, fundamentado no interacionismo simbólico, realizado com oito técnicos de enfermagem da Estratégia Saúde da Família de um município brasileiro de médio porte. Os dados foram coletados por meio de entrevista semiestruturada e analisados segundo a análise de conteúdo temática. A pesquisa foi aprovada no Comitê de Ética em Pesquisa. Os participantes identificam que a Estratégia Saúde da Família realiza basicamente ações curativas e pautam como atribuições cotidianas: pré-consulta, pós-consulta e procedimentos de enfermagem. As tecnologias relacionais foram apontadas como o principal instrumento de trabalho. Como finalidade do trabalho elencaram que é atender a demanda espontânea. Constata-se que o processo de trabalho dos técnicos de enfermagem está voltado predominantemente para ações curativas no plano individual, o que reforça o modelo de atenção centrado na doença. Sugere-se a realização de educação permanente para ressignificar o trabalho desses profissionais. Por fim, ressalta-se a necessidade de repensar a formação dos técnicos em enfermagem, de modo que eles desenvolvam competências esperadas para atuação nos serviços de atenção primária à saúde, que atendam às necessidades de saúde da população, na ótica da integralidade da atenção à saúde e para o estabelecimento de processos de trabalho que considerem os determinantes, os riscos e danos à saúde.
A crioterapia capilar como estratégia na redução da alopecia induzida pela quimioterapia oncológica: revisão sistemática
Authors: Monteiro Debora Esteves , Fialho Isabelle Cristine Tavares Silva , Ramos Flávia Cristina de Souza , Oliveira Renata Martins Mendes de , Nascimento Camila Telles do , Souza Osinete Martins de , Fuly Patrícia dos Santos Claro
Published: October 2021

Objetivo: Analisar as evidências disponíveis sobre o uso da técnica de crioterapia capilar, na redução da alopecia em pacientes oncológicos submetidos à quimioterapia e suas repercussões para o cuidado de enfermagem. Método: Revisão sistemática baseada nas recomendações do checklist PRISMA, sem restrições de datas, nas bases: Pubmed, Cinahal, Cochrane e Scopus. Resultados: De 579 artigos publicados, 10 foram incluídos publicados entre 2015 a 2020. Pacientes que utilizaram a terapia foram mais bem sucedidos quanto à preservação capilar, variando entre 45,6% de resposta com avaliação de grau 3 de alopecia, a 89% com taxa maior que 50% de alopecia utilizando taxanos. É importante ressaltar que existem casos de insucesso ou de queda parcial e os fatores que podem influenciar esse resultado. Conclusão: Foi evidenciada a efetividade da técnica e a importância da enfermagem neste processo no intuito de proporcionar uma melhor qualidade de vida e tratamento destes pacientes.
Manejo cirúrgico de dentes natais e neonatais em pacientes com fissura labiopalatina – Relato de Casos
Authors: Santos Isabella Mousinho Marinho dos , Carvalho Lucia Rosa Reis de Araújo , Carvalho Luciano Reis de Araújo , Carvalho Marcius Vinicius Reis de Araújo
Published: October 2021

Fundamento: Dentes natais são definidos como dentes presentes ao nascimento, enquanto elementos dentários neonatais são os que eclodem em até 30 dias após esse evento, sendo estas alterações da normalidade mais frequentes em bebês portadores de fissuras labiopalatinas. O tratamento conservador consiste em acompanhamento nos casos em que não há prejuízo à mãe e à criança. No entanto, a presença desses elementos pode causar desconforto durante a sucção, laceração dos seios da mãe e aspiração dos dentes, necessitando de remoção cirúrgica. Objetivo e relato de caso: o objetivo do trabalho é apresentar dois casos de dentes natal e neonatal em bebês com fissura labiopalatina. O primeiro caso destina-se ao relato de um dente neonatal na região anterior de mandíbula. O segundo, em sequência, relata a presença de dente natal em região maxilar, sendo ambas dentições decíduas. O tratamento de escolha para os dois casos supracitados envolveu a remoção dos elementos e posterior acompanhamento, terapêutica escolhida em decorrência das dificuldades de sucção, mobilidade que pode predispor à aspiração acidental do elemento pelo bebê, ferimentos ao seio materno durante a amamentação e prejuízo em moldagens nos casos em que há a necessidade da confecção de placas intraorais para auxiliar na alimentação. Conclusão: Apesar do tratamento conservador constituir uma opção viável em alguns casos de dentes natais e neonatais em pacientes com fissura labiopalatina, a remoção cirúrgica é a terapêutica eficaz nos casos em que o elemento dentário ocasiona prejuízos significativos à mãe e ao bebê.
Biometria e Potencial Germinativo em Sementes de Peltophorum dubium (Sprengel) Taubert – Fabaceae
Authors: Duarte Daniela Fialho , Giacomelli Felipe Brancalion , Fernandes Simone Yasuda , Souza Bianca de Oliveira , Morais Glaucia Almeida de
Published: October 2021

A crescente busca por sementes de alta qualidade para reflorestamento tem aumentado o interesse pelos conhecimentos relacionados à biologia de sementes como as características biométricas, com intuito de tornar mais viável à produção de mudas de algumas espécies. Assim, objetivou-se no presente estudo analisar a biometria de sementes de diferentes matrizes de Peltophorum dubium (Spreng) Taubert, e relacioná-la ao potencial germinativo e à intensidade de dormência em diferentes tamanhos de sementes. As sementes foram coletadas em 12 matrizes e avaliadas quanto ao comprimento, largura, espessura e massa. Os dados obtidos foram submetidos a testes para a comparação das matrizes, verificação de relação entre as variáveis e para definição de categorias de sementes com base nas classes de massa (pequenas, médias e grandes). O potencial germinativo de cada matriz e das três categorias de sementes foi avaliado comparando sementes intactas e sementes submetidas à quebra de dormência em ácido sulfúrico. Os dados de germinação foram utilizados para os cálculos de porcentagem, frequência relativa, índice de velocidade e tempo médio. As matrizes e as categorias foram comparadas estatisticamente por análise de variância. A correlação dos dados biométricos das sementes mostrou-se positivamente significativa para todas as comparações, com associações mais fortes para as associações com massa, variável utilizada para a definição das categorias de tamanho. As sementes escarificadas obtiveram, em média, 90% de germinação enquanto o controle 4%. As sementes médias e grandes apresentaram maior desempenho germinativo, sem influência do regime de luz (luz contínua e fotoperíodo de 12 horas). Concluímos neste estudo que sementes de Peltophorum dubium se assemelham biometricamente a lotes provenientes de regiões geograficamente mais próximas e que existe variabilidade entre matrizes, sendo este um fator importante para a manutenção das populações. Além disso, observamos também que a variável massa é um parâmetro adequado para a seleção de sementes com maior potencial germinativo.
Polymorphisms in the Leptin and SCD genes in Buffaloes of the Amazon
Authors: Silva Caio Santos , Silva Filho Ednaldo da , Silva Lorena Keyse Nery da , Ferraz Rafaella Sousa , Matos Amanda de Sousa , Marques Larissa Coelho , Sales Rodrigo Lima , Guimarães Diva Anelie de Araújo , Marques José Ribamar Felipe
Published: October 2021

The objective this work was to evaluate genetically the buffaloes populations using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in the leptin and stearoyl-CoA desaturase (SCD) genes, and associate the genotypes with milk production. Sixty-nine samples of Bubalus bubalis - 38 Murrah breed, 18 Mediterranean and 13 mixed-breed of the Murrah with Mediterranean - were evaluated. Allele and genotype frequencies, the heterozygosity observed and expected, the inbreeding coefficients (FIS), the probabilities of the Hardy-Weinberg equilibrium, the F statistic for population differentiation and Shannon index were calculated using GENEPOP and GenALEx programs. The associations of the different genotypes with a role in milk production were tested by Analysis of Variance (ANOVA) and t-test. We reported the leptin and SCD allele contribution to genetic variability in buffaloes herds in the Brazilian Amazonian region. The A allele was more representative in leptin and SCD genes for all breed groups. No significant effects between genotypes and milk production were found in the present study, but there is an indicative that AA genotype in leptin gene affects milk production in Murrah breed.
A importância do papel do enfermeiro na humanização do parto: verificação completiva
Authors: Hora Aline Barreto , Santos Anne Karolyne Silva , Oliveira Cristiane Santana de , Feitosa Maiza Conceição Gonzaga de Oliveira , Teles Weber de Santana , Silva Max Cruz da , Calasans Taíssa Alice Soledade , Barros Ângela Maria Melo Sá , Torres Ruth Cristini , Azevedo Marcel Vinícius Cunha , Andrade Ana Fátima Souza Melo de , Santos Junior Paulo Celso Curvelo , Debbo Alejandra , Silva Maria Hozana Santos
Published: October 2021

It is an integrative review that started the searches through the choices of scientific articles published between the years 2016 to 2021. Therefore, through the results brought in this study, there is the identification and description with the synthesis of the articles that deal with on the subject addressed in this research. According to Lima et al. (2020), the effective participation of the obstetric nurse in monitoring labor and birth qualifies teamwork and contributes to humanized care. The development of the work allowed us to understand that the obstetric nurse has the necessary technical knowledge for the development of this practice, mainly because it is a situation in which the doctor is not fully present or because he cannot be during the entire process due to the time it takes. With this, the professional will be able to use their professional preparation to work directly with the pregnant woman, providing all the necessary care and clarification, talking, reassuring, indicating the options and encouraging the parturient to face the birth with comfort, safety and less pain.
Roberto Mange, a criação do Centro Ferroviário de Ensino e Seleção Profissional (CFESP) e a formação para o trabalho nas décadas de 1930 e 1940
Authors: Assis Sandra Maria de , Costa Karoline Louise Silva da , Medeiros Neta Olívia Morais de
Published: October 2021

O objetivo deste artigo é explicitar as articulações que envolveram Roberto Mange e a criação e funcionamento do Centro Ferroviário de Ensino e Seleção Profissional (CFESP), criado em 1934, para formar e selecionar ferroviários. A pesquisa insere-se no campo da História da Educação Profissional e justifica-se pela importância do CFESP para qualificação e racionalidade da formação dos operários das ferrovias, além de ter originado   outros Centros Ferroviários de Ensino e Seleção Profissional no Brasil. A metodologia utilizada foi a pesquisa documental e bibliográfica através de autores como Zanetti (2001), Fonseca (1961); Cunha (2000), Pedrosa (2014), Ciavatta (2009), dissertações e teses. A trajetória profissional de Roberto Mange relaciona-se com a criação, em 1923, do curso de Mecânica Prática do Liceu de Artes e Ofícios de São Paulo; com criação da Escola Profissional Mecânica, em 1924;   com  a criação do Curso de Ferroviários de Serviço de Ensino e Seleção Profissional da Sorocabana e criação do Instituto de Organização Racional do Trabalho (IDORT), ambos em 1931;  e  finalmente, a criação do CFESP destinado  à formação de trabalhadores para as ferrovias em São Paulo e outros estados brasileiros. Concluímos que a análise apresentou elementos que corroboram   a argumentação sobre o papel do engenheiro Mange nas ações relacionadas à racionalização do trabalho e aplicação dos métodos de gestão científica, favorecendo a cooperação entre as estradas de ferro e os poderes públicos.
The Effect of Customer Experience and Customer Engagement Through Customer Loyalty on Sales Revenue Achievement at PT United Tractors
Authors: Permadi Andrie , Silalahi Sukardi
Published: October 2021

This study aims to examine and discuss the influence of the quality of Customer Experience and Customer Engagement with the mediation of Customer Loyalty which is thought to affect repurchase intention or in other words the achievement of sales revenue as a company performance. The variables in this study were measured through the dimensions of accessibility, service competence, customer recognition, commitment, customer value, thrust, personalization, consistency, perceived quality and customer certainty to make repeat purchases.

The number of respondents involved in this study were 200 respondents, all respondents were United Tractors consumers who had purchased products and services from PT United Tractors. This research is a quantitative approach that uses an instrument in the form of a questionnaire. Research data were analyzed using SEM (Structural Equation Modeling) analysis strategy with the help of SPSS and AMOS programs and the results of the analysis in this study also show that customer loyalty can mediate the effect of Customer Experience and Customer Engagement on Repurchase Intention
Exploration of Multi Meeting, Multitasking and Meeting Fatigue to Productivity
Authors: Maharani Anita , Marlika Selvia , Triyanti Triyanti , Pandu Thenry Linda Sharron
Published: October 2021

This study aimed to see the effect of multi-meeting, multitasking, and meeting fatigue on productivity. The context of this study is during the Covid-19 pandemic, where phenomena related to multi-meeting, multitasking, and meeting fatigue were entirely natural. The literature used is related to multi-meeting, multitasking, and meeting fatigue, as well as productivity. We elaborate on several pieces of literature before the pandemic, and this study emerges from the results of studies during the pandemic. This research method refers to a quantitative approach, which wants to see the relationship between variables;  SMART PLS a test tool. The researcher conducts a reliability test by looking at CR and AVE, a validity test by looking at discriminant validity, and finally, conducting a path analysis by looking at the results of P-Values. This study indicates that meeting fatigue does not negatively affect productivity; multitasking has a positive effect on productivity, meeting fatigue can affect productivity when there are multi meetings as moderators, and multitasking affects productivity when there are multi meetings as moderators.
Development of an Information System for Solving the Problem of Optimal Crops Placement
Authors: Mirzataev S.
Published: October 2021

This article describes the Farm Optimization Model information system and the procedure for its operation which is developed for the optimal placement of crops and increase the efficiency of land use on farms.
Criminal Liability of Medical Workers Under the Legislation of the Kyrgyz Republic
Authors: Iriskulbekov E. , Osmonbaeva K.
Published: October 2021

The article considers both specific and general corpus deeds for which medical workers can be prosecuted under the Criminal Code of the Kyrgyz Republic of February 2, 2017, highlights the elements of corpus deeds, draws conclusions about the inconsistency in the application of certain crimes against medical workers.
Multi-paradigm Approaches to Training in Mechanical Engineering: In Diagrams and Commentary
Authors: Galkina A. , Grishan I.
Published: October 2021

This article is devoted to the analysis of electronic resources of mechanical engineering — engineering education and training of engineering personnel in the era of INDUSTRIALIZATION 4.0. The paper is based on the statistics of the Science and Education Electronic Resources Pool (SEERF) from 1998 up to present. The information on developments in engineering education and their statistical processing is automated by collector_stat program developed by personnel of the JERLF. The electronic resources of education in the field of mechanical engineering are presented by technical universities of the country. Thus, the object of the research is technical universities. The subject of the study is electronic resources of education in the field of mechanical engineering. The methods of research are methods of statistics, content analysis, logic.
The World of Ch. Aitmatov in Interpretation and Perception
Authors: Turgunova G.
Published: October 2021

Research relevance: In the works of Ch. Aitmatov, the cardinal problems of mankind are mainly considered, through which various sections and layers of life are realistically described in their contradiction and dialectical relationship. Research objectives: to reveal the world of Ch. Aitmatov through the interpretation and perception of the works by the readers, to experience, to sympathize with the heroes of the work, and thus, as it were, he makes them responsible for everything that happens on Earth. Research methods and materials: the article is based on a literary review and analysis of the works of the great writer Ch. Aitmatov. Research results: The world of Aitmatov is a world where kindness, love, compassion, respect, friendship and honesty live, and all this is the essence of the Universe itself. The Universe is immense, the Universe is limitless, but it fits into a small human heart, he carries it with him, he lives in it, and he cannot but obey its laws. Conclusions: Modern challenges urge people to be accountable to the Universe and to humanity.
Batik Mega Mendung sebagai Ide Perancangan Kemasan
Authors: Abdullah Farid , Riyanti Menul Teguh , Basar Suhaila Bt. , Sobandi Bandi , Rinjani Dian
Published: October 2021

Abstrak Permasalahan kemasan (packaging) pada saat ini berkait erat dengan masih rendahnya pemahaman produsen dalam membuat kemasan yang mampu mengangkat nilai isi produk di dalamnya. Bahkan masih banyak produk berkualitas yang belum dikemas secara baik, kurang estetik, dan mampu menjelaskan isi produk dengan memadai. Potensi budaya setempat seperti motif batik, juga masih berjalan sendiri dan belum banyak diangkat menjadi bagian dari suatu kemasan. Motif batik Mega Mendung, Cirebon sudah menjadi ikon motif batik Jawa Barat adalah satu motif yang dapat diangkat menjadi bagian dari kemasan. Tulisan ini memakai metode deskriptif-kualitatif untuk menciptakan kemasan sesuai potensi daerah Trusmi, Cirebon, Jawa Barat. Temuan dari tulisan ini adalah suatu produk yang didesain kemasan secara estetis dan ergonomis, memudahkan pembeli dalam mengenal budaya setempat menjadi lebih baik. Kata Kunci: batik, desain, ide, kemasan, Mega Mendung AbstractThe problem of packaging at this time is closely related to the minor understanding of producers in making packaging that can lift the value of the contents of the product. There are still many quality products that have not the package properly, limited aesthetic, and can’t be able to explain the contents of the product adequately. Potential of local culture such as batik motifs, also still run by themselves, and not many have designated as part of a package. Mega Mendung, Trusmi, Cirebon batik pattern has become an icon of West Java batik pattern that delegated as part of the package medium. This paper uses a descriptive-qualitative method to create packaging according to the regional potential of the Trusmi, Cirebon, West Java region. The findings of this paper are a product that designed aesthetically and ergonomically designed, making it easier for buyers to get to know the local culture better. Keywords: batik, design, idea, Mega Mendung, packaging
Revisiting the Bible Translation of Robert Morrison and William Milne
Authors: Lee Archie C. C.
Published: October 2021

The article revisits the collaborative project of two early missionaries to China, Robert Morrison and William Milne, who overcame the ‘practical impossibility’ of translating the Protestant Bible into Chinese in 1823. The issues of the doctrinal constraints, the influence of the contemporary English translations, faithfulness to the Hebrew text and cultural sensitivity to the target language will be raised with reference to concrete examples cited from their joint translation version. The creation account of Genesis and passages on the rendering of the biblical ‘sea monsters’ into Chinese will be selected for focused study in order to show how Morrison and Milne were influenced by the KJV but at times departed from it in their reading of the original Hebrew text. Furthermore, it is also noted that they have shown a certain degree of sensitivity to the Chinese cultural context in their choice of terminology in translating the biblical text into Chinese.
Individualized approach to predicting complications of acute myocardial infarction in patients with chronic obstructive pulmonary disease
Authors: Naumov A. V. , Prokofieva T. V. , Polunina O. S. , Saroyants L. V. , Polunina E. A.
Published: October 2021

Objective. Development of an algorithm for predicting the complicated course of acute MI (rhythm disturbances, acute left ventricular failure: pulmonary edema, cardiogenic shock) in patients with COPD.

Materials and methods. 37 patients with acute myocardial infarction on the background of COPD were examined, undergoing inpatient treatment in the conditions of the regional vascular center of the State Budgetary Healthcare Institution of the Alexandro-Mariinsky Regional Clinical Hospital in 2017–2019. Clinical examination included assessment of complaints, life history and illness. The enzyme-linked immunosorbent assay was used to determine: the concentration of the HSP 70 protein using the HSP 70 High Sensitivity EIA Kits (Stressgen, USA), interleukins IL‑1β, IL‑2, IL‑6 with reagent kits of VEKTOR-BEST JSC (St. Novosibirsk, Russia) and neopterin test with the Neopterin ELISA kit (IBL International, Germany). Determination of the content of apoptotic cells from heparinized venous blood was performed using the Annexin-V-FITC / 7AAD reagent kit (Beckman Coulter, USA). Statistical data processing was carried out using the SPSS 26.0 (USA).

Results. When analyzing the frequency of occurrence of the studied laboratory diagnostic signs, significant differences were found for the indices of circulating annexin V mononuclear cells at an early stage of apoptosis and neopterin. Based on the data obtained and the selection of predictors, the probability of complications (rhythm disturbances, acute left ventricular failure) was calculated using the logistic regression equation. Using ROC analysis, a cut-off was determined for the levels of circulating annexin V mononuclear cells at an early stage of apoptosis and neopterin.

Conclusion. Information on the estimated high risk of developing complications of acute myocardial infarction, such as rhythm disturbances and acute left ventricular failure, will help to purposefully select the amount of preventive and therapeutic measures in patients with acute MI associated with COPD to minimize this risk.
Another Criterion For The Riemann Hypothesis
Authors: Vega Frank
Published: October 2021

Let's define $\delta(x) = (\sum_{{q\leq x}}{\frac{1}{q}}-\log \log x-B)$, where $B \approx 0.2614972128$ is the Meissel-Mertens constant. The Robin theorem states that $\delta(x)$ changes sign infinitely often. Let's also define $S(x) = \theta(x) - x$, where $\theta(x)$ is the Chebyshev function. It is known that $S(x)$ changes sign infinitely often. We define the another function $\varpi(x) = \left(\sum_{{q\leq x}}{\frac{1}{q}}-\log \log \theta(x)-B \right)$. We prove that when the inequality $\varpi(x) \leq 0$ is satisfied for some number $x \geq 3$, then the Riemann hypothesis should be false. The Riemann hypothesis is also false when the inequalities $\delta(x) \leq 0$ and $S(x)\geq 0$ are satisfied for some number $x \geq 3$ or when $\frac{3 \times \log x + 5}{8 \times \pi \times \sqrt{x} + 1.2 \times \log x + 2} + \frac{\log x}{\log \theta(x)} \leq 1$ is satisfied for some number $x \geq 13.1$.
Effects of Temporal Crop Diversification of a Cereal-Based Cropping System on Generalist Predators and Their Biocontrol Potential
Authors: Puliga Giovanni Antonio , Thiele Jan , Ahnemann Hauke , Dauber Jens
Published: October 2021

In agroecosystems, crop diversification plays a fundamental role in maintaining and regenerating biodiversity and ecosystem services, such as natural pest control. Temporal diversification of cropping systems can affect the presence and activity of natural enemies by providing alternative hosts and prey, food, and refuges for overwintering. However, we still lack studies on the effects of temporal diversification on generalist predators and their biocontrol potential conducted at field scale in commercial agricultural settings. Here, we measured proxies of ecosystem functions related with biological pest control in 29 commercial agricultural fields characterized by cereal-based cropping system in Lower-Saxony, northern Germany. The fields differed in the number of crops and cover crops cultivated during the previous 12 years. Using the Rapid Ecosystem Function Assessment approach, we measured invertebrate predation, seed predation and activity density of generalist predators. We aimed at testing whether the differences in the crop rotations from the previous years would affect activity of predators and their predation rates in the current growing season. We found that the length of the crop rotation had neutral effects on the proxies measured. Furthermore, predation rates were generally lower if the rotation comprised a higher number of cover crops compared to rotation with less cover crops. The activity density of respective taxa of predatory arthropods responded differently to the number of cover crops in the crop rotation. Our results suggest that temporal crop diversity may not benefit the activity and efficiency of generalist predators when diversification strategies involve crops of very similar functional traits. Adding different resources and traits to the agroecosystems through a wider range of cultivated crops and the integration of semi-natural habitats are aspects that need to be considered when developing more diverse cropping systems aiming to provide a more efficient natural pest control.
Flotation of Smithsonite From Quartz Using Pyrophyllite Nanoparticles as the Natural Non-toxic Collector
Authors: Pan Gaochan , Zou Dan , Wang Zhen
Published: October 2021

The use of natural hydrophobic mineral nanoparticles as a collector in froth flotation has recently attracted the attention of researchers. In this article, the separation performance and mechanism of pyrophyllite nanoparticles (PNPs) on smithsonite and quartz flotation system were investigated using the method of flotation, zeta potential, contact angle, and scanning electron microscope (SEM)/energy disperse spectroscopy (EDS). The results of single mineral flotation showed that the difference in flotation recovery between smithsonite and quartz was large for NaOL, DDA, and PNP collectors in the acidic pH range, the largest of which was the PNP system. At pH 6, the optimal dosage of PNPs was 1,000 mg/L. Separation of mixed minerals of smithsonite and quartz using a PNP collector provides the optimum concentrate index (Zn grade 50.84% and Zn recovery 85.36%). According to the results of zeta potential measurement, PNPs and quartz were negatively charged, and the surface of smithsonite was positively charged at pH 6. This provided conditions for smithsonite to selectively adsorb PNPs due to different electrostatic forces. Selective adsorption of PNPs in the smithsonite/quartz flotation system was directly observed by SEM/EDS detection. Hydrophobic PNPs were adsorbed on the surface of hydrophilic smithsonite to make it hydrophobic, and the surface of quartz remained hydrophilic. This is the mechanism for separating smithsonite and quartz using PNPs.
Non-pharmaceutical Interventions for Hypertrophic Cardiomyopathy: A Mini Review
Authors: He Miaomiao , Qiu Jie , Bai Yang , Wang Yan , Hu Mei , Chen Guangzhi
Published: October 2021

Hypertrophic cardiomyopathy is an inherited cardiovascular disease, and 70% of patients have left ventricular outflow tract obstruction. Ventricular septal myectomy has been the gold standard treatment for most patients with refractory symptoms. Due to higher mortality associated with medical facilities with less experience, alcohol septal ablation has been accepted as an alternative to conventional surgical myectomy. It offers lower all-cause in-hospital complications and mortality, which could be potentially more preferable for patients with serious comorbidities. In recent years, radiofrequency ablation, providing another option with reproducibility and a low risk of permanent atrioventricular block, has become an effective invasive treatment to relieve left ventricular outflow tract obstruction. Moreover, substantial progress has been made in gene therapy for hypertrophic cardiomyopathy. The principal objective of this review is to present recent advances in non-pharmaceutical interventions in hypertrophic cardiomyopathy.
Brugada Syndrome: Warning of a Systemic Condition?
Authors: D'Imperio Sara , Monasky Michelle M. , Micaglio Emanuele , Ciconte Giuseppe , Anastasia Luigi , Pappone Carlo
Published: October 2021

Brugada syndrome (BrS) is a hereditary disorder, characterized by a specific electrocardiogram pattern and highly related to an increased risk of sudden cardiac death. BrS has been associated with other cardiac and non-cardiac pathologies, probably because of protein expression shared by the heart and other tissue types. In fact, the most commonly found mutated gene in BrS, SCN5A, is expressed throughout nearly the entire body. Consistent with this, large meals and alcohol consumption can trigger arrhythmic events in patients with BrS, suggesting a role for organs involved in the digestive and metabolic pathways. Ajmaline, a drug used to diagnose BrS, can have side effects on non-cardiac tissues, such as the liver, further supporting the idea of a role for organs involved in the digestive and metabolic pathways in BrS. The BrS electrocardiogram (ECG) sign has been associated with neural, digestive, and metabolic pathways, and potential biomarkers for BrS have been found in the serum or plasma. Here, we review the known associations between BrS and various organ systems, and demonstrate support for the hypothesis that BrS is not only a cardiac disorder, but rather a systemic one that affects virtually the whole body. Any time that the BrS ECG sign is found, it should be considered not a single disease, but rather the final step in any number of pathways that ultimately threaten the patient's life. A multi-omics approach would be appropriate to study this syndrome, including genetics, epigenomics, transcriptomics, proteomics, metabolomics, lipidomics, and glycomics, resulting eventually in a biomarker for BrS and the ability to diagnose this syndrome using a minimally invasive blood test, avoiding the risk associated with ajmaline testing.
Geologic Controls on Erosion Mechanism on the Alaska Beaufort Coast
Authors: Ravens Thomas M. , Peterson Sasha
Published: October 2021

Two prominent arctic coastal erosion mechanisms affect the coastal bluffs along the North Slope of Alaska. These include the niche erosion/block collapse mechanism and the bluff face thaw/slump mechanism. The niche erosion/block collapse erosion mechanism is dominant where there are few coarse sediments in the coastal bluffs, the elevation of the beach below the bluff is low, and there is frequent contact between the sea and the base of the bluff. In contrast, the bluff face thaw/slump mechanism is dominant where significant amounts of coarse sediment are present, the elevation of the beach is high, and contact between the sea and the bluff is infrequent. We show that a single geologic parameter, coarse sediment areal density, is predictive of the dominant erosion mechanism and is somewhat predictive of coastal erosion rates. The coarse sediment areal density is the dry mass (g) of coarse sediment (sand and gravel) per horizontal area (cm2) in the coastal bluff. It accounts for bluff height and the density of coarse material in the bluff. When the areal density exceeds 120 g cm−2, the bluff face thaw/slump mechanism is dominant. When the areal density is below 80 g cm−2, niche erosion/block collapse is dominant. Coarse sediment areal density also controls the coastal erosion rate to some extent. For the sites studied and using erosion rates for the 1980–2000 period, when the sediment areal density exceeds 120 g cm−2, the average erosion rate is low or 0.34 ± 0.92 m/yr. For sediment areal density values less than 80 g cm−2, the average erosion rate is higher or 2.1 ± 1.5 m/yr.
Integrated Energy System Optimal Operation in Coal District With Hydrogen Heavy Trucks
Authors: Yin Junjie , Wang Jianhua , You Jun , Chen Hong , Shi Wei
Published: October 2021

The coal industry contributes significantly to the social economy, but the emission of greenhouse gases puts huge pressure on the environment in the process of mining, transportation, and power generation. In the integrated energy system (IES), the current research about the power-to-gas (P2G) technology mainly focuses on the injection of hydrogen generated from renewable energy electrolyzed water into natural gas pipelines, which may cause hydrogen embrittlement of the pipeline and cannot be repaired. In this paper, sufficient hydrogen energy can be produced through P2G technology and coal-to-hydrogen (C2H) of coal gasification, considering the typical scenario of coal district is rich in coal and renewable energy. In order to transport the mined coal to the destination, hydrogen heavy trucks have a broad space for development, which can absorb hydrogen energy in time and avoid potentially dangerous hydrogen injection into pipelines and relatively expensive hydrogen storage. An optimized scheduling model of electric-gas IES is proposed based on second-order cone programming (SOCP). In the model proposed above, the closed industrial loop (including coal mining, hydrogen production, truck transportation of coal, and integrated energy systems) has been innovatively studied, to consume renewable energy and coordinate multi-energy. Finally, an electric-gas IES study case constructed by IEEE 30-node power system and Belgium 24-node natural gas network was used to analyze. The results show that by introducing the proposed hydrogen production technology, typical daily operating costs are effectively reduced by 7.7%. Under China’s carbon emissions trading system, the operating costs of hydrogen heavy trucks have been reduced by 0.95 and 4.68% respectively, compared with electric vehicles and diesel trucks. Under Europe’s stricter carbon emissions trading system, the percentages of cost reduction are 2.56 and 9.12%, respectively. The above technical results verify the feasibility, economy, low carbon, and effectiveness of the proposed mechanism.
The Sensory and Cognitive Ecology of Nectar Robbing
Authors: Richman Sarah K. , Barker Jessica L. , Baek Minjung , Papaj Daniel R. , Irwin Rebecca E. , Bronstein Judith L.
Published: October 2021

Animals foraging from flowers must assess their environment and make critical decisions about which patches, plants, and flowers to exploit to obtain limiting resources. The cognitive ecology of plant-pollinator interactions explores not only the complex nature of pollinator foraging behavior and decision making, but also how cognition shapes pollination and plant fitness. Floral visitors sometimes depart from what we think of as typical pollinator behavior and instead exploit floral resources by robbing nectar (bypassing the floral opening and instead consuming nectar through holes or perforations made in floral tissue). The impacts of nectar robbing on plant fitness are well-studied; however, there is considerably less understanding, from the animal’s perspective, about the cognitive processes underlying nectar robbing. Examining nectar robbing from the standpoint of animal cognition is important for understanding the evolution of this behavior and its ecological and evolutionary consequences. In this review, we draw on central concepts of foraging ecology and animal cognition to consider nectar robbing behavior either when individuals use robbing as their only foraging strategy or when they switch between robbing and legitimate foraging. We discuss sensory and cognitive biases, learning, and the role of a variable environment in making decisions about robbing vs. foraging legitimately. We also discuss ways in which an understanding of the cognitive processes involved in nectar robbing can address questions about how plant-robber interactions affect patterns of natural selection and floral evolution. We conclude by highlighting future research directions on the sensory and cognitive ecology of nectar robbing.
The Eyes Are More Eloquent Than Words: Anticipatory Looking as an Index of Event Memory in Alzheimer's Disease
Authors: Hanazuka Yuki , Futamura Akinori , Hirata Satoshi , Midorikawa Akira , Ono Kenjiro , Kawamura Mitsuru
Published: October 2021

Alzheimer's disease (AD) is a disorder in which individuals experience a difficulty in maintaining event memory for when, where, who, and what. However, verbal deficiency, one of the other symptoms of AD, may prevent a precise diagnosis of event memory because existing tests are based on verbal instructions by the tester and verbal response from patient. Therefore, non-verbal methods are essential to evaluate event memory in AD. The present study, using eye tracking, investigated whether AD patients deployed anticipatory looking to target acts related to future events based on previous experience when an identical video was presented to them twice. The results revealed the presence of anticipatory looking, although AD patients were unable to verbally report the content of the video. Our results illustrate that AD patients have a one-time event memory better than previously thought.