bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence of asthma among children in India
Authors: Daniel Roy Arokiam , Aggarwal Praveen , Kalaivani Mani , Gupta Sanjeev Kumar
Published: July 2022

There is a lack of national-level estimates on the magnitude of asthma among children in India. Hence, we undertook a systematic review and meta-analysis to estimate the prevalence of asthma among children in India. We searched PubMed, Embase, Cochrane Library, and Google Scholar, and included cross-sectional studies reporting data on the prevalence of asthma among children in India. A random-effects model was used to estimate the pooled prevalence of asthma. In the 33 selected studies (pooled sample of 167,626 children), the estimated prevalence of asthma was 7.9% (95% confidence interval: 6.3–9.6%), I2 = 99.1% (P < 0.001). The prevalence was higher among boys and in urban areas. Appropriate training and resources should be made available at the primary healthcare level for early detection and management of asthma in children. A nationwide population-based survey is indicated to provide reliable estimates of the burden of asthma.
Management of oral mucositis caused by radiotherapy – A comprehensive review
Authors: Singh Manisha , Bagewadi Anjana
Published: July 2022

Oral cancer is the malignant neoplasm involving the oral cavity. The treatment of oral cancer is surgery, radiotherapy, and adjuvant chemotherapy. Oral mucositis is the most common side effect when radiotherapy treatment for oral cancer is indicated. High.grade oral mucositis results in the delay of the radiotherapy treatment and increases the cost of maintenance. The preventive measures for radiation.induced mucositis include maintaining oral hygiene, treatment of xerostomia, diet modifications, and low.level laser therapy. This article provides a guide for the practicing oncologists about the current treatment, advances in treatment, and alternative medicine for improving radiation.induced mucositis.
Desmoplastic ameloblastoma of maxilla - A case report
Authors: Mishra Puja Darshana , Raj Kumar N. Govind , Kumar A. Sudarshan , Karri Roja Lakshmi , Ashok Sahana
Published: July 2022

Desmoplastic ameloblastoma is an unusual type of ameloblastoma which varies substantially from other variants of ameloblastoma. This case report describes a case of desmoplastic ameloblastoma in a 40-year-old male patient who presented with a swelling in the right maxillary anterior region which was painless in nature. The patient was apprehensive about the asymmetry caused by the massive tumor. Initially, conventional computed tomography was done, and the diagnosis was confirmed by histopathology. Surgical resection of the tumor was done, and a prefabricated prosthetic splint was given postoperatively. The surgical site healed completely, and there was no recurrence at 6-month follow up. The present case report emphasizes the specific histological features of the tumor. Due to its invasive nature, early intervention is needed to reduce the disfigurement, functional hindrance, and other complications caused by the tumor.
Healed injury in a nektobenthic trilobite: “Octopus-like” predatory style in Middle Ordovician?
Authors:   Institute of Geology and Paleontology, Faculty of Science, Charles University in Prague, Czech Republic, Fatka Oldrich , Budil Petr ,   Czech Geological Survey, Prague, Czech Republic, Mikulaš Radek ,   Institute of Geology, Academy of Sciences of the Czech Republic, Prague, Czech Republic
Published: July 2022

The Lower Paleozoic sediments of the Barrandian area are globally renowned as a classical example of well-preserved skeletal marine fauna, including abundant remains of trilobites. Several tens of morphologically anomalous exoskeletons of trilobites have been collected and documented from Cambrian to Devonian clastic sediments and carbonates. One of them, an exceptionally well preserved, articulated and partly enrolled exoskeleton of the Ordovician nektobenthic trilobite Parabarrandia bohemica (NOVÁK, 1884) exhibits a prominent palaeopathological anomaly in its pygidium. We interpret this anomaly as a healed traumatic injury and attribute this damage to a failed predatory attack. The subsequently healed injury is classified as the ichnogenus Oichnus BROMLEY, 1981. The structure on the pygidium is strongly reminiscent of injuries caused by octopods and a large cephalopod is proposed as a potential durophagous predator responsible for the herein described trilobite injury. However, an attack from an unknown arthropod while the trilobite was in a soft-shelled stage cannot be excluded.
Response to Visceral Leishmaniasis Cases through Active Case Detection and Vector Control in Low-Endemic Hilly Districts of Nepal
Authors: Banjara Megha Raj , Joshi Anand Ballabh , Singh Vivek Kumar , Das Murari Lal , Gurung Chitra Kumar , Olliaro Piero , Halleux Christine , Matlashewski Greg , Kroeger Axel
Published: July 2022

The visceral leishmaniasis (VL) elimination program in Nepal has largely completed the attack phase and is moving toward consolidation and maintenance phases. New VL foci are, however, appearing in Nepal, and therefore new innovative community-centered strategies need to be developed and tested. We conducted early case detection by an index case–based approach and assessed the feasibility, efficacy, and cost of an intervention for sandfly control through indoor residual spraying (IRS) or insecticidal wall painting (IWP) in new and low-endemic districts Palpa and Surkhet. IRS was performed in 236 households and IWP in 178 households. We screened 1,239 and 596 persons in Palpa and Surkhet, respectively, resulting in the detection of one VL case in Palpa. Both IWP and IRS were well accepted, and the percentage reductions in sandfly density after 1, 9, and 12 months of intervention were 90%, 81%, and 75%, respectively, for IWP and 81%, 59%, and 63% respectively for IRS. The cost per household protected per year was USD 10.3 for IRS and 32.8 for IWP, although over a 2-year period, IWP was more cost-effective than IRS. Active case detection combined with sandfly control through IWP or IRS can support to VL elimination in the consolidation and maintenance phase.
Bacterial Contamination of Ultrasound and Stethoscope Surfaces in Low- and High-Resource Settings
Authors: Heldeweg Micah L. A. , Berend Kenrick , Cadenau Laura , Rosingh Andert , Duits Ashley J. , van Mansfeld Rosa , Tuinman Pieter R.
Published: July 2022

Point-of-care ultrasound is an accurate diagnostic and monitoring tool. Its increasing affordability, portability, and versatility make it an excellent component of standard clinical evaluation alongside the stethoscope. However, like the stethoscope, ultrasound carries risks of surface contamination and potential cross-infection. In this international observational study, we compared the surface contamination of ultrasound equipment to stethoscopes in two medical centers: a tropical low-resource hospital and academic high-resource hospital. Ultrasound equipment and coupling gel had similar prevalence of microbial surface contamination compared with observed stethoscopes. Most microbes were commensal Gram-positive, but some were opportunistic and pathogenic microbes (such as Escherichia coli and Staphylococcus aureus). In conclusion, it is crucial to appreciate and reduce the risk of ultrasound device contaminations. When ultrasound is used bedside, similar to stethoscopes, conscientious hygiene measures are equally fundamental.
Bibliografía de Carmen Pensado
Authors: Pensado Carmen
Published: July 2022

Bibliografía de Carmen Pensado
Gebelikte Yaşanan Görsel ve Bedensel Değişikliklerin Postpartum Dönemdeki Bedeni Beğenme ve Psikolojik Yakınmalarla İlişkisi
Authors: FIŞKIN Gamze , IŞIK Cansu
Published: July 2022

Giriş: Tarih boyunca süregelen kadınların kozmetik endişeleri gebelikle birlikte artış gösterebilmektedir. Bu süreçte ortaya çıkan görsel/fiziksel değişikliklerin bedensel memnuniyeti etkilediği ve postpartum dönemde bir takım psikolojik olumsuz durumlara neden olabileceği bildirilmektedir. Amaç: Gebelik döneminde yaşanan görsel/bedensel değişimlerin postpartum psikolojik durumlarla ilişkisini belirlemek amaçlanmıştır. Yöntem: Tanımlayıcı ve ilişki arayıcı olarak planlanan araştırmanın evrenini, 18 yaş ve üzerinde olan, postpartum 42 günü aşmamış kadınlar oluşturmuştur. 20 Ekim 2020-20 Ocak 2021 tarihleri arasında araştırmaya dâhil edilme kriterlerini karşılayan tüm lohusalar sosyal medya üzerinden online olarak davet edilmiştir (n=207). Veriler lohusa bilgi formu, Bedeni Beğenme Ölçeği, Depresyon, Anksiyete, Stres Skalası kullanılarak toplanmıştır. Verilerin analizinde tanımlayıcı istatistikler, bağımsız örneklem t testi, one way ANOVA testleri kullanılmış olup değişkenler arasındaki ilişki Pearson korelasyon analiziyle test edilmiştir. Bulgular: Lohusaların yaş ortalamasının 29.502 (±4.394), %59.4’ünün fazla kilolu ve %70.0’ının planlı gebelik yaşadığı tespit edilmiştir. Gebelik süresince 14.758 (±5.063) kilo alan lohusaların postpartum süreleri ortalama 21.570 (±11.710) gün olarak saptanmıştır. Çoğunluğu gebelik sürecinde çok kilo aldığını, iştahının arttığını, postür bozukluğu yaşadığını ve memelerinin aşırı büyüyerek hassaslaştığını ifade etmiştir. Lohusaların vücutlarından postpartum süreçte memnun olduğu ve psikolojileriyle arasında negatif yönlü zayıf bir ilişki bulunduğu görülmüştür (r = -.202, p = .003). Sonuç: Araştırmaya katılan lohusaların depresif belirti göstermediği fakat orta düzeyde anksiyete, hafif düzeyde stres yaşadıkları bulunmuştur. Bu bakımdan gebeliğin ilerleyen periyotlarından itibaren görsel/bedensel şikâyetleri olduğu fark edilen riskli grupların önceden tespit edilmesi ve postpartum süreçteki emosyonel sorunları önleme/tedavi etme programlarının geliştirilmesi önem taşımaktadır.
Assessing the argumentation ability of pre-service teachers. Case study concerning the chemical dissolution process
Authors: Cebrián-Robles Daniel , Hierrezuelo Osorio José , Franco Mariscal Antonio Joaquín , Cruz Lorite Isabel María
Published: July 2022

The scientific argumentation ability of pre-service teachers (PSTs) in the early stages of education is essential as they will provide students with their initial grounding in the scientific knowledge. A total of 133 pre-service Early Childhood (PSEC) and Primary (PSP) School teachers undertook an argumentation activity concerning how the dissolution process takes place. The design of this activity is as a clear example of the different levels of complexity of the argumentation ability in science. The results show that PSTs consolidated the categories identification of evidence and construction of warrant. However, the abilities to provide a counter-critique and construct a comparative argument are still not consolidated. The Mann-Whitney U test did not show any significant differences between groups with high levels of difficulty. In contrast, we found statistically significant differences for the identification of evidence in favour of PSPs.
Perceptions of university students about virtual reality as a didactic resource: a pre-experimental study with a control and experimental group
Authors: Menjívar Valencia Eduardo , Sánchez Rivas Enrique , Ruiz Palmero Julio , Guillén Gámez Francisco David
Published: July 2022

This article presents the results of a study of the impact of incorporating Second Life on the didactics of a university degree subject as well as on student satisfaction, administering a survey to two groups of students enrolled in the same subject through a 24-item questionnaire scored on a 5-point Likert scale for data collection. Subjects comprised 75 students who used the traditional model and 75 students who used a virtual reality model. To verify the hypotheses, the data analysis focused on the descriptive statistics through a comparison of the mean scores for the dependent variables of each of the groups, and with the verification of parametric assumptions, statistical inference was applied to determine the significance of the variances through Student’s t-test. The results show that students perceive specific advantages linked to the design of VR activities in virtual reality. Hence, the potential of virtual reality for improving the teaching process is confirmed. This study leads to the conclusion that students at Universidad Don Bosco greatly value the teaching learning process mediated by virtual reality.
The Impact of Devolution on Social Policy
Authors: Birrell Derek
Published: July 2022

With new devolved administrations in Scotland, Wales and Northern Ireland, this book provides a study of developments in the major areas of social policy and a full comparison between the four UK nations.
The British Immigration Courts
Authors: Travers Max
Published: July 2022

Immigration has been a controversial and contentious area of public policy since the Commonwealth Immigration Act ended most primary immigration in 1962. This study looks in detail at the work of practioners in the court-system that hear appeals from immigrants and asylum seekers against decisions made by the British Government. The book contains chapters about decision making in primary purpose and the asylum appeals, the administrative problems faced by successive British governments, and the perspectives of pressure groups and politicians. The British Immigration Courts transforms our understanding of immigration as a political issue through preserving a sense of routine work in the courts, civil service and political process which is ignored or idealised by other approaches. It is essential reading for practioners, academics and students interested in current debates about policy.
Planning with Children for Better Communities
Authors: Freeman Claire , Henderson Paul , Kettle Jane
Published: July 2022

In addition to clarifying why the issue of children's participation should be prioritised, this book uses examples and case studies from a variety of professions and disciplines in order to explain different methods that can be used to support participation.
The Widening Gap
Authors: Shaw Mary , Dorling Daniel , Gordon David , Davey Smith George
Published: July 2022

This report presents critical new evidence on the size of the widening health gap. New geographical data are presented and displayed in striking graphical form. The Widening Gap should be read alongside Inequalities in Health: The Evidence Presented to the Independent Inquiry into Inequalities in Health (The Policy Press, 1999).
Domestic Violence and Health
Authors: Williamson Emma
Published: July 2022

This book examines the relationship between health and domestic violence. In a qualitative study of the attitudes of health professionals and the women with whom they come into contact, it gives voice to a range of issues which urgently need to be addressed providing guidance for training and practice, as well as recommendations for policy makers.
Unfolding Lives
Authors: Thomson Rachel
Published: July 2022

A unique approach to understanding the changing face of youth transitions, addressing the question of how gender identities are constituted in late modern culture.
PILOTAŽA KAO POMOĆNA USLUŽNA DELATNOST U PLOVIDBI
Authors:   University of Belgrade, Faculty of Law, Jovanović Nebojša
Published: July 2022

In this contribution for the conference, the author explains pilotage as an auxiliary activity aimed to support safety navigation, as a main activity. He explains its role within the maritime navigation, as well as within the inland navigable waterways. On the first place, the work stress duty of a prudent navigation for all her participants, its significance for the safety navigation, the basic elements of her organisation, as well as auxiliary activities that serve to increase it safety. The central part of the work is explanation of pilotage, where the author gives its notion, legal sources of her regulation, types, organisation and legal status of a locman (i.e. pilot). This work does not deal with the private law questions within pilotage, such as contract of pilotage or liability of pilot, but just with public law questions. The conclusion is that the Serbian rules on pilotage are very strict, but that they at the same time do not protect domestic pilotage companies from the foreign competitors. Such a liberal attitude toward the foreign competitors are not known almost anywhere in the world.
NASTANAK, RAZVOJ, SADAŠNjOST I BUDUĆNOST BANKARSTVA U OBAVLjANjU USLUŽNE DELATNOSTI
Authors:   Faculty of Legal and Business Studies ", Milosavljević Miroslav ,   Dr. Lazar Vrkatić",   in Novi Sad, Milosavljević Nikov Jelena
Published: July 2022

A significant segment in service law is banking. The first reason for that is the great role that banking has in the economic system of every country with a market economy, while the second reason is that public and private interests are realized on the basis of banking operations. Banking performs a specific activity, which differs from the activity of other business entities and which makes it recognizable on the market, since this activity cannot be performed by other entities (receiving deposits and giving loans). From the above, there is a need to study the historical development of banking, its present and based on that project the future of banking, in order to be ready to face all the challenges that will arise in the future and thus preserve business positions in a strong and competitive market economy. The historical method, as well as the normative and comparative method were used in the study of the subject of this paper.
POJAM FIDUCIJARNOG PRENOSA SVOJINE KAO REALNE GARANCIJE
Authors:   University of Kragujevac, Faculty of Law, Pavićević Aleksandra
Published: July 2022

The subject of this paper is a critical analysis of the concept of fiduciary transfer of property, as a specific real guarantee in modern comparative civil and commercial law. This legal construction has been functioning in European legal practice for a long time, and in some legislations as a reaffirmed real guarantee originating from Roman law, suitable to satisfy various interests of counterparties in the sphere of providing financial and banking services. Since positive Serbian Real law does not regulate this institute, the aim of the paper is to assess the existing legal and doctrinal provisions of this legal construction in foreign regulations, as well as in drafts of domestic laws de lege ferenda. The author estimates that this is a useful institute, which should be included in list of domestic rights of security rights in rem de lege ferenda (which is its higher gender term) and which is also in line with the solution of the "soft" EU law, with which we are trying to harmonize the domestic solution. As the most significant differentia specifica in this concept, the author singles out: the creation of a guarantee by specific division of property powers between the trustee and the beneficiary, with the possible lack of publicity (ability to conceal debt and debtors' creditworthiness) and reduced formalities in the exercise of the right of settlement - which are significant advantages over liens, as the most related institute.
VERSICHERBARE RISIKEN IN DEN BEREICHEN SANIERUNG UND REVITALISIERUNG VON ALTBAUTEN
Authors: Rohrbach Wolfgang
Published: July 2022

Das umfangreiche europäische Kulturerbe an Altbauten bzw. Baudenkmälern ist -insbesondere, wenn es sich um prunkvolle Wohn- oder Repräsentationsbauten handelt-, oft mit enormen Investitionslasten verbunden. Wenn Gebäude dann noch unter Denkmalschutz stehen, müssen Instandhaltung und Revitalisierungsmaßnahmen nach bestimmten Vorgaben erfolgen. Eigentümer (=Bauherren), Bauunternehmer bzw. auf aufwändige Tätigkeiten spezialisierte Einzelpersonen wie zB. Restauratoren tragen also eine große Verantwortung. Sie alle werden bei Revitalisierungsprojekten, immer wieder mit Haftungsfragen konfrontiert. Erschwerend wirkt, dass es Überschneidungsbereiche gibt. „Wann, wer wofür haftet.“ Die Risiken teilen sich in versicherbare und unversicherbare, wobei es auch hier fließende Grenzen gibt. Im Gegenzug können Eigentümer / Pächter jener kunstvoll gestalteten Altbauten über den facettenreichen Kulturtourismus zu Einkünften kommen, die ihre Investitionen auch geschäftlich rechtfertigen. Dabei genießen Letztere zusätzlich ein Ambiente, das Lebensqualität repräsentiert. Kunst kann Schönheit, Harmonie und interessante Botschaften vermitteln. Damit wird eine Sehnsucht gestillt, die in jedem Menschen existiert. Kunstgegenstände, oder Kunstdenkmäler können aber auch als Wertanlage dienen, oder zu Forschungs- und Lehrzwecken verwendet werden. Diese Multifunktionalität sichert Kunstdenkmälern bzw. – bauten in vielen Sektoren und Branchen Anerkennung. Eine Brücke, Unterführung oder Straße würde auch ohne Verzierungen ihre Funktion im Straßenverkehr erfüllen. Aber viele Benützer wollen “ ein schönes Umfeld, weil sie sich dann wohl fühlen“. Wenn jemand ein Baukunstwerk erwirbt, dann möchte er meist seine unmittelbare Umgebung interessanter oder „schöner“ gestalten. Der Wert eines Kunstwerkes hängt also erst in zweiter Linie vom Preis des eingesetzten oder verwendeten Materials ab. Viel wichtiger ist die Botschaft, die uns von den Kunstschaffenden über Skulpturen, Bilder, Texte usw. vermittelt wird. Ein guter Versicherungsschutz ist in solchen Fällen sehr wichtig, da die Behebung auftretender Schäden um ein Vielfaches teurer sein kann als bei herkömmlichen Standardbauten. Um herauszufinden, welche Versicherungskombinationen sinnvoll sind, ist bei Baudenkmälern ein vorangehendes Risikomanagement durch einen Versicherungsexperten empfehlenswert. Durch eine professionelle Risikoidentifikation und Risikobewertung können aus Versicherungsbündeln, die richtigen „Bausteine“ ausgewählt werden. Gebäudeversicherungen, die erforderlichenfalls mit Elementar- und Haushaltsversicherungen kombiniert werden, sind die eine relevante Gruppe für Eigentümer (und Pächter oder Mieter). Die Bauwesen- oder Bauleistungsversicherungen sind im Fall notwendiger Bauvorhaben die zweite relevante Gruppe.
OBAVEZNO OSIGURANjE PUTNIKA U JAVNOM PREVOZU OD POSLEDICA NESREĆNOG SLUČAJA
Authors:   University of Kragujevac, Faculty of Law, Miladinović Zoran
Published: July 2022

Transport of passengers in all branches of traffic by the nature of things and one type of dangerous activity. The possibility of an accident in public transport of passengers is a real fact, therefore special regulations regulate the obligations of the owners of transport to conclude a contract on insuring their liability for the consequences and damages that passengers and third parties suffer from their means, or from their activities, before putting them into traffic. It is a form of compulsory insurance against the consequences of an accident. That means that a passenger who is injured in a traffic accident in public transport is entitled to the sum insured on the basis of compulsory passenger insurance and compensation from carrier(there is possibility of accumulating compensation). The importance of this insurance is in the fact that passengers in public transport are covered by insurance under the law itself, which means that they are entited to compesationeven when the carrier has not concluded a passenger insurance contract or if the insurer with whom the insurance contract fell into bankruptcy. In the Republic of Serbia, this issue is well regulated by a separate Law on compulsory traffic insurance, whole provisions are mainly of imperative nature. It defines the persons who are obliged to obtain insurance policy for the transport of passengers, then identifies the persons who have passenger status, in terms of insurance policy, as well as prescribes the minimum amount of compensation that is covered by the insurance policy.
Pengaruh Latihan Small Sided Games 2 v 2 + 4 Terhadap Peningkatan VO2MAX Pada Siswa SSB Putra WMC Serdang Bedagai
Authors: Putra Angga Dwi , David Siahaan
Published: July 2022

Dalam permainan sepakbola dibutuhkan kondisi fisik yang baik untuk memudahkan pemain dalam memaksimalkan keterampilan bermain sepakbola. Salah satu kondisi fisik yang harus diperhatikan dalam permainan sepakbola adalah daya tahan aerobik VO2max. Untuk meningkatkan daya tahan aerobik (VO2max) perlu dilakukan latihan yang terencana secara sistematis. Salah satu latihan yang dapat dilakukan yakni latihan Small Sided Games 2 v 2 + 4. Penelitian ini dilakukan dengan tujuan untuk mengetahui pengaruh latihan Small Sided Games 2 v 2 + 4 terhadap VO2Max pada siswa SSB Putra WMC. Metode penelitian yang digunakan adalah metode eksperimen, desain penelitian adalah True Experimental Desiign dengan Pretest-Posttest Control Group Design. Instrumen yang digunakan dalam penelitian ini menggunakan tes Multistage Fitnes Test (MFT). Sampel penelitian adalah siswa SSB Putrs Wmc yang berjumlah 16 anak. Teknik analisis data menggunakan uji t dengan signifikansi 5%. Berdasarkan  hasil perhitungan dengan uji Paired Sample T Test diperoleh nilai sig. (2 tailed) sebesar 0,002 < 0,05 maka dapat disimpulkan ada perbedaan rata-rata antara pre-test dan post-test kelas eksperimen. Dari hasil perhitungan yang telah dilakukan dapat dilihat terdapat peningkatan rata-rata hasil pre-test dan post-tes kelas eksperimen dari 32,8 menjadi 41,4.  Dengan demikian dapat disimpulkan terdapat pengaruh yang signifikan sebelum dilakukan (Pre-test) latihan Small sided games 2 v 2 + 4 dan setelah dilakukan (post-test) latihan Small sided games 2 v 2 + 4 terhadap Vo2max siswa SSB Putra WMC Serdang Bedagai tahun 2021.
The Use of Oral Human Grade Ivermectin with Supplements Known as Immunomodulators for Treating Patients with COVID-19 Infections at Home
Authors: Vergeire-Dalmacion Godofreda R
Published: July 2022

Background: Several meta-analyses have shown low to moderate certainty for Ivermectin (IVM) to reduce all-cause mortality from COVID -19 infection by 68% and to prevent infection by about 86%.

Objectives: The aim of our study is to determine the effects of oral IVM for treating mild to moderate COVID infections and the effects of demography, symptomatology, co-morbidities, IVM dose and combination or single immunomodulating supplements on clinical recovery

Method: A cross-sectional design covering the period of April 2021 to June 2021 was used. The participants were clinicians in Metro Manila who prescribed IVM for home care treatment of their COVID-19 patients.

Result: Out of 338 evaluable patients, 95.6% (323/338) showed full recovery at the end of the study, 0.59% (2/338) was still recovering, 2.36% (8/338) are long haulers and 1.47% (5/338) succumbed to the infection. Mild cases received IVM at 0.2 to 0.8 mg/kg body weight (kgbw) and 1.0 to 1.8 mg /kgbw for moderate cases for 5-7 days. The p-values of 0.022 for gender and 0.000 for co-morbidity showed that these factors can significantly affect the recovery of COVID-19 patients. Shortness of breath (p-value of 0.000), muscle pain (p-value =.002) and headache (p-value=0.011) have significant effects on recovery. Among the co-morbidities, hypertension (p-value=0.000), diabetes (p-value=.006), cardiovascular diseases (p-value=0.001) and obesity (p-value=0.014) have statistical significant effects on clinical outcomes. Using Kruskal Wallis H statistics, the intake of combination immunomodulators has significant effect on the recovery of COVID-19 patients (p-value of 0.027). Using Mann-Whitney statistics, Zinc alone showed statistically significant effect (p-value of 0.002) for recovering from COVID.

Conclusion: IVM is effective for COVID infections provided it is given early and the dose is adjusted for severity and co-morbidities. The graduated dose regimen of IVM and the predilection of the virus to mutate will become a challenge for designing future randomized clinical trials.
Full Mouth Implant Rehabilitation Using Fixed Detachable Bio-HPP Frameworks in the Presence of One-piece Implants: A Clinical Report
Authors: Hanno Kenda I
Published: July 2022

Background: The purpose of this case report is to describe a case of full arch rehabilitation in the maxilla and mandible using fixed detachable BioHPP frameworks veneered with prefabricated veneers in the presence of one-piece implants.

Methods and findings: A 63-year-old male patient presented with a maxillary acrylic resin fixed restoration supported on six implants and a mandibular implant retained overdenture on two one-piece implants. Five implants were placed in the mandible in addition to the existing two one-piece implants using CAD/CAM surgical guides. Steps for prosthetic construction of the final full arch BioHPP restorations were completed. The mandibular BioHPP framework was relieved during construction to accommodate the one-piece implants. Cement was applied to fill the space in the framework above the one-piece implants.

Conclusion: Full arch screw-retained restorations can be fabricated in the presence of one-piece implants without sectioning of the abutment part to avoid patient discomfort and heat generation. The low modulus of elasticity of BioHPP along with prefabricated PMMA veneers provided a major advantage over other materials by dampening the occlusal forces and reducing debonding rates.
Conservative Treatment of Medial Shaft Clavicle Fracture with Borderline Criteria: A Case Report
Authors: Gurrieri Luca
Published: July 2022

Clavicle fractures account for 3% of all fractures in adult population. Usually, surgical treatment is the gold standard for fracture with dislocation > 2 cm, shortening > 2 cm and angulation > 30 ° or comminution, especially in young or active patients, due to the relatively high risk of non-union. In our study, we report the case of a 50-years old patient, with high functional requests, with a middle shaft clavicle fracture, presenting borderline criteria. We treated him conservatively with figure of 8-bandage for five weeks. After removal of the bandage, patient performed physiotherapy and at final follow-up patient showed a nearly complete ROM despite a non-optimal radiographic outcome. Conservative treatment is a valid option in borderline middle shaft fractures, even in mature patient requiring high functional outcomes.
Simulated courtroom trials: a challenging learning activity
Authors: Martí Roser Casanova , Domènech Federic Adán , Guri Elisabet Cerrato , Junoy Joan Picó i
Published: July 2022

In this paper we report a learning experience taught by lecturers in Procedural Law at the Universitat Rovira i Virgili (URV). This innovative experience comprises the simulation of courtroom trials in the field of Procedural Law and is taught to first-year undergraduate Law students taking the Introduction to Procedural Law course. These simulated courtroom trials, which aim to provide students with practical experience, are highly satisfactory in terms of the students’ acquisition of theoretical and practical skills.  Implementing this learning experience at the beginning of the degree enables first-year students to quickly become familiar with all aspects of real trials and the practices employed in courts and tribunals. Moreover, the students improve their oral skills by conducting a simulation of oral proceedings and their writing skills by drafting a report on their simulated courtroom trial
Natural infection with black point (Alternaria sp.) of cultivars and advanced bread wheat lines during the crop season 2018-2019
Authors: Fuentes-Dávila Guillermo , Torres-Cruz María Monserrat , Rosas-Jáuregui Ivón Alejandra , Félix-Fuentes José Luis , Félix-Valencia Pedro
Published: July 2022

Veintiniún líneas avanzadas de trigo harinero y las variedades Borlaug 100, Norman F2008, Ónavas F2009 y Roelfs F2007 se evaluaron para resistencia a la punta negra durante el ciclo agrícola otoño-invierno 2018-2019 en el Campo Experimental Norman E. Borlaug. Las fechas de siembra fueron noviembre 12 y 22, 2018. La cosecha se hizo a mano y la evaluación mediante inspección visual contando el número de granos sanos e infectados en 10 espigas por línea y de esta forma se calculó el porcentaje de infección. El rango de infección para la primera fecha de siembra fue de 0 a 15.1% con un promedio de 3.3, y para la segunda fue de 0 a 7.6% con un promedio de 0.8. Dentro de las categorías de infección del grupo en base al promedio de los datos de las dos fechas, 4 líneas no presentaron granos infectados, 11 y las variedades  Borlaug 100, Ónavas F2009 y Roelfs F2007 estuvieron en la categoría 0.1-2.5%, 2 y la variedad Norman F2008 en la de 2.6-5.0% y 4 líneas en la de 5.1-10.0%. Las líneas que presentaron los porcentajes de infección más altos fueron SOKOLL*2/3/BABAX/LR42//BABAX, BORL14*2/5/ATTILA/3* BCN*2//BAV92/3/KIRITATI/WBLL1/4/DANPHE y PBW343//CAR422/ANA/3/ELVIRA con 15.1, 11.4 y 10.8%, respectivamente, todas en la primera fecha.
Perancangan Generator Satu Fasa Magnet Permanen Fluks Radial Kecepatan Rendah
Authors: Manggala Fredson Bully , Syafriyudin Syafriyudin , Suyanto Muhammad
Published: July 2022

Energi listrik merupakan bagian penting dalam kehidupan manusia. Pada daerah terpencil dibutuhkan pembangkit listrik yang dapat memenuhi kebutuhan energi listrik. Generator dengan magnet permanen kecepatan rendah dapat menjadi alternatif karena tidak menimbulkan polusi. Penelitian ini membahas generator dengan magnet permanen kecepatan rendah dengan memanfaatkan mesin listrik tipe JY2B – 2. Perancangan rotor dilakukan dengan meletakkan magnet permanen neodymium N52 dengan dimensi 6 cm x 1 cm x 0,5 cm. Stator diperoleh dari mesin tipe JY2B – 2. Pengujian tanpa beban dilakukan pada rpm 375 menghasilkan tegangan sebesar 58,1 Volt dan frekuensi 50,13. Pengujian pada rpm 375 dengan menggunakan kapasitor 5 μF menghasilkan tegangan 62,6 Volt, kapasitor 7 μF menghasilkan tegangan 63,4 Volt, dan kapasitor 10 μF menghasilkan tegangan 64,4 Volt. Pengujian dengan penambahan kapasitor menyebabkan kenaikan tegangan. Pada pembebanan resistif 10 sampai 45 Watt, generator mengalami penurunan tegangan dari 58,1 Volt sampai 41,7 Volt dan kenaikan arus 0,14 Ampere sampai 0,52 Ampere. Pembebanan resistif dengan penambahan kapasitor 10 μF terjadi penurunan tegangan generator dari 64,4 Volt sampai 44,8 Volt dan kenaikan arus dari 0,15 Ampere sampai 0,53 Ampere. Semakin meningkat nilai daya beban menyebabkan penurunan nilai tegangan terminal sedangkan nilai arus berbanding lurus dengan daya beban
Visualizing Coatnet Predictions for Aiding Melanoma Detection
Authors:   Carebot s.r.o, Prague, Czech Republic, Kvak Daniel
Published: July 2022

Melanoma is considered to be the most aggressive form of skin cancer. At present, the evaluation of malignancy is performed primarily by invasive histological examination of the suspicious lesion. Developing an accurate classifier for early and efficient detection can minimize and monitor the harmful effects of skin cancer and increase patient survival rates. Due to the similar shape of malignant and benign cancerous lesions, doctors spend considerably more time when diagnosing these findings. However, using a deep learning approach as a computer vision tool can overcome some of the challenges. This paper proposes a multi-class classification task using the CoAtNet architecture, a hybrid model that combines the deep depthwise convolution matrix operation of traditional convolutional neural networks with the strengths of Transformer models and self-attention mechanics to achieve better generalization and capacity. The model was evaluated based on precision, recall, and AP. The proposed multi-class classifier achieves an overall precision of 0.901, recall 0.895, and AP 0.923, indicating high performance compared to other state-of-the-art networks. The proposed approach should provide a less complex framework to automate the melanoma diagnostic process and speed up the life-saving process.
Physical Fitness Degradation of the Elementary School Students: A Case on Gorontalo City, Indonesia
Authors:   Department of Physical Education, Health and Recreation, Universitas Negeri Gorontalo, Indonesia
Published: July 2022

The ongoing debates on physical literacy in the realm of public physical fitness (PF) in Indonesian literature has resulted in various surprising but exciting facts. However, most of the existing studies on PF have generally pivoted around the quantitative tradition. With this reality in mind, qualitatively empirical study scrutinizing the actual factors veiled within the current state of PF of the society, the primary school students, in particular, remains somewhat of a mystery, given far too little attention has been paid to the investigation of such an inquiry in the Indonesian context. The present study, therefore, was initiated to address this gap. As a manifestation of the past evaluative research on the physical literacy of Elementary School (ES) students in Gorontalo City, this qualitative case study specifically sought to determine the causal factors underlying the PF degradation in ES students in Gorontalo City. As many as 26 informants consisting of 20 ES physical education teachers and six school principals were selected as the research participants. The research data were collected using structured interviews and documents. The findings of this study revealed four main factors lying behind the PF degradation of ES students in Gorontalo City. These four causal factors are: 1) the disparity of the teaching and learning of physical education within the thematic system of the 2013 curriculum, 2) the loss of open spaces in the schools due to the misinterpretation of the school administrators about the Adiwiyata program launched by the government, 3) the booming presence of Smartphones amongst students, which somehow brings about a tendency for students to spend more time sitting without making any significant movements, and 4) the poor implementation of legal product pertaining to sports which include the National Sports Law No. 3 of 2005, 2 Presidential Instructions and 2 Regulations of the Minister of Youth and Sports as proclaimed by the government.
Innovative Technologies to Improve the Spirituality of the Youth during the Global Changes
Authors:   Lecturer, Department of National Ideology, Fundamentals of Spirituality and Legal Education, Chirchik State Pedagogical Institute of Tashkent region, Khudayberganovich Tashmetov Tukhtasin
Published: July 2022

In today's era of global changes, special attention is being paid to the effective use of innovations based on new ideas and best international practices in the system of continuing education in the Republic of Uzbekistan. After all, the President of the Republic of Uzbekistan Sh.M. Mirziyoyev said, “Innovation is the future. If we start building our great future today, we must start it on the basis of innovative ideas, innovative approaches.” Indeed, behind the experience of leading foreign countries in ensuring the quality and effectiveness of education, which is effectively applied in the practice of the republican system of continuing education, a special place belongs to modern interactive methods, which are the basis of innovative technologies to increase learning activity.
Agradecimiento a los revisores y actividad editorial de la revista Metro Ciencia en 2021
Authors: Campos-Miño Santiago
Published: July 2022

Metro Ciencia es una revista científica de difusión del conocimiento en ciencias de la salud. Los manuscritos presentados deben pasar un proceso de análisis y recomendaciones por parte de un selecto grupo de revisores expertos sobre cada uno de los temas presentados.
Colitis microscópica en adultos mayores de 18 años en el Hospital Metropolitano desde enero del año 2013 a diciembre del año 2019
Authors: Altamirano Fabián , Vinueza Ana María , Tello-Montúfar Denisse , Fors Lopez Martha
Published: July 2022

Introducción: La colitis microscópica es una causa habitual de diarrea crónica no inflamatoria, más común en mujeres alrededor de los 55 años, cuyo diagnóstico se basa en el estudio de las muestras de biopsias de colonoscopia, con las variantes linfocítica o colágena. El objetivo del presente trabajo es establecer la prevalencia de la enfermedad en el Hospital Metropolitano e identificar los factores de riesgo asociados a la enfermedad. Métodos: Estudio observacional, transversal y retrospectivo. Se realizó una revisión de la historia clínica de todos los pacientes con diagnóstico de colitis y enteritis no especificadas con realización de colonoscopia en nuestra institución entre el 1 de enero de 2013 al 31 de diciembre del 2019. Resultados: La prevalencia de la colitis microscópica fue del 12.3% con un predominio de las colitis linfocitarias (11,0%). El 74,3% de los sujetos fueron del sexo femenino. Le edad media de los pacientes con colitis microscópica fue de 41 años y el número medio de diarreas de 4,9. La mayoría de los sujetos participantes tenían una obesidad por encima de los 30 kg/m2 (83,4%) sin embargo, esta condición no estuvo asociada con la colitis microscópica. Se evidenció diferencia estadística significativa en el número de diarreas entre pacientes con colitis microscópica y los sujetos con otros tipos de colitis. Se demostró que el tener más de 5 diarreas es un factor de riesgo (OR=7,79) teniendo las personas con más de 5 diarreas 7 veces más posibilidad de tener una colitis microscópica. Conclusiones: La prevalencia de colitis microscópica fue de 12,8%, con aparición más frecuente en mujeres. Se evidenció que más de 5 diarreas pudiera estar relacionado con la presencia de esta enfermedad.
Adecuación del esfuerzo terapéutico orientado hacia un buen morir
Authors: Montenegro Chamorro Carlos Danilov , Maldonado Cando Freddy Marcelo
Published: July 2022

El presente trabajo es una revisión teórica descriptiva de conceptos asociados a la limitación o adecuación del esfuerzo terapéutico, un tema controvertido que va teniendo un papel importante en el medio hospitalario y con mayor énfasis en la unidad de cuidados intensivos debido a los avances tecnológicos y médicos que apuntan hacia la preservación de la vida, sin embargo, en determinadas ocasiones toda tecnicidad profesional no consigue ese logro tan deseado o si se logra, es a costa de unas condiciones de vida precaria que terminan desarrollando una muerte lenta poco razonable, conllevando al aumento del sufrimiento de pacientes, familiares y médicos. Esta realidad cada vez supone la discusión entre los beneficios que se pretenden, o se pueden conseguir, con las terapias y la carga o exceso que se le impone al paciente, provocando dificultades para la toma de decisiones tanto para personal médico y familiares, incluyendo conflictos éticos y legales. Ante esta disyuntiva se pretende, como objetivo, abordar distintos puntos de vista de autores e investigadores que permita sintetizar, diferenciar y comparar criterios sobre el tema, así como el análisis bioético relacionados con la práctica de la adecuación del esfuerzo terapéutico.
Factores de riesgo y abordajes terapéuticos en infarto agudo de miocardio con elevación del segmento ST
Authors: Montiel Carduz Jorge , Portillo Barrios Camila , Popoff Duarte Elena , Franco Benítez Pablo , Contrera González Rocío , Maidana Fernández Hector
Published: July 2022

El infarto agudo de miocardio con elevación del segmento ST es una de las urgencias más comunes, la carga que denotan los factores de riesgo están relacionadas directamente con la ocurrencia del evento coronario, el tiempo de evolución es uno de los principales condicionantes del abordaje terapéutico.
Osteonecrosis maxilar en síndrome antifosfolipídico. Revisión de la literatura a propósito de un caso
Authors: Cedillo Bailón Marco , Sandoval Vernimmen Fernando , Sandoval Portilla Fernando
Published: July 2022

El síndrome antifosfolipídico (SAF) fue descrito por primera vez en 1983 por Hughes y se caracteriza por ser un trastorno autoinmune sistémico que genera trombosis venosa o arterial de manera recurrente, así como morbilidad obstétrica debido a la producción persistente de anticuerpos antifosfolipídicos (aFL). La trombofilia puede aparecer en diferentes sistemas y órganos, incluyendo el tejido óseo. Esta afección puede desarrollarse especialmente en pacientes que acumulan factores de riesgo como lo son enfermedades autoinmunes, corticoterapia, exposición a trauma local e infecciones crónicas. En el presente artículo se realizó una revisión de la literatura referente al SAF y se presenta un caso de osteonecrosis maxilar luego de un procedimiento de extracción dental en un paciente con SAF primario. Además, se expone la osteonecrosis como una posible complicación de esta enfermedad para lo cual se plantean algunas alternativas de tratamiento.
Progresos genéticos y genómicos en el cáncer de mama
Authors: Paz-y-Miño César
Published: July 2022

Se presenta una revisión sobre el estado del conocimiento de la genética y la genómica del cáncer de mama. Se hace referencia a estudios globales sobre genes de predisposición a este tipo de cáncer, así como genes de apoyo al diagnóstico y tratamiento. Adicionalmente se nombran algunos genes útiles en el trabajo clínico y en el manejo del cáncer de mama.
Presentación de un caso y revisión de la literatura, linfoma hepático primario
Authors: Paz y Miño M Juan José , Nieto Ramos Carlos Javier
Published: July 2022

Paciente femenina de 63 años, con 15 días de malestar general, temperatura de 40 °C y dolor abdominal difuso. A la examinación, el abdomen con Murphy positivo, el borde hepático a 2 cm del reborde costal, resto de examen sin datos. En exámenes monocitosis, PCR y enzimas hepáticas elevadas, patrón colestásico; virus hepatotropos, no hepatotropos y estudios reumatológicos negativos. La TAC de tórax y abdomen negativas.
UNIVERSIDAD Y SOCIEDAD, COMO EJE DE PROMOCIÓN DEL DESARROLLO SOCIAL
Authors: Loor-Rodríguez Carlos David , Guerrero-Reyes Leonardo Jacinto , Delgado-Vera Nathaly Estefanía
Published: July 2022

El desarrollo humano como proceso individual, tiene como fin desplegar capacidades particulares pero con el propósito de extender los beneficios de ese desarrollo a un entorno más próximo y consecutivamente hasta llegar a uno más general. Esta investigación se planteó como objetivo general caracterizar universidad y sociedad como eje de promoción social, abordado como una investigación documental. Reflejando que en esa evolución humana toma parte la Universidad en conjunto con la Sociedad, dado que mediante los esfuerzos de ambas se propician actividades que generan cambios para elevar los estándares de vida no solo del individuo o ser humano, sino del mimo como un ente perteneciente a una sociedad. A través de los cambios en las capacidades del sujeto, y gracias a las labores de extensión e investigación de la Universidad, se pueden establecer planes de acción que solucionen problemáticas de su entorno, logrando promocionar a su vez su desarrollo social.
ESTRATEGIAS DE MARKETING DE SERVICIOS PARA LA FIDELIZACIÓN DE LOS CLIENTES DE LA EMPRESA AJE, UBICADA EN LA CIUDAD DE GUAYAQUIL
Authors: De la Llana-Pérez Evelyn , Valenzuela-Velasco Cesar Andrés
Published: July 2022

AJE es una empresa que presenta deficiencias en la prestación de servicio al cliente, es en atención a esto que la presente investigación plantea estrategias de marketing de servicios para la fidelización de los clientes de la empresa AJE, ubicada en la ciudad de Guayaquil. Se trata de una investigación mixta: cualitativa y cuantitativa, en la que se aplica el método descriptivo, explicativo. Los métodos empíricos fueron la entrevista, utilizando la encuesta y la observación como instrumentos de recolección de información. Los resultados de los instrumentos aplicados indican que los clientes consideran que el servicio al cliente es el factor más importante a la hora de adquirir productos. La implementación de estrategias de marketing de servicios basadas en un protocolo de atención, seguimiento a clientes, atención por canales de interacción virtual, un programa de recompensas y educación a clientes en marketing y ventas; influyen positivamente en la fidelización de clientes minoristas de la empresa AJE, al sentir que la empresa se preocupa más de ellos.