bluuebunny/crossref_metadata_2025 huggingface dataset:
Persepsi Mahasiswa Terhadap Program Kebijakan Merdeka Belajar Kampus Merdeka
Authors: Anwar Rosyida Nurul
Published: March 2023

Penelitian ini bertujuan untuk mengetahui persepsi mahasiswa Pendidikan Guru Pendidikan Anak Usia Dini (PG PAUD) tentang kebiijakan Merdeka Belajar Kampus Merdeka (MBKM). Metode yang digunakan adalah kuantitatif deskriptif. Responden adalah mahasiswa program studi PG PAUD sebanyak 28 mahasiswa yang terdiri dari 10 responden berasal dari angkatan 2020/2021 dan sebanyak 18 berasal dari angkatan 2021/2022. Hasil penelitian menunjukkan bahwa sebanyak 96% mengetahui dan pernah mendengar akan adanya kebijakan MBKM, akan tetapi hanya 11% yang mengetahui kebijakan program secara keseluruhan, dan hanya 4% yang tidak mengetahui sama sekali. Minat mahasiswa mengikuti kegiatan MBKM sebanyak 89% sedangkan program pertukaran mahasiswa merdeka dan kampus mengajar yang menjadi kegiatan yang paling banyak diminati mahasiswa. Melalui program MBKM, mahasiwa dapat meningkatkan hard skill dan soft skill guna mewujudkan pendidikan berkualitas untuk semua.
Pengaruh Penggunaan Media Aplikasi Canva Terhadap Hasil Belajar Mahasiswa Pada Mata Kuliah Konsep Dasar IPS
Authors: Thesalonika Emelda , Arent Ease
Published: March 2023

Tujuan pada riset ini untuk mengetahui seberapa besar pengaruh penggunaan media canva bagi mahasiswa PGSD dalam mengikuti matakuliah Konsep Dasar Pembelajaran IPS. Tipe riset yang dipakai ialah riset kuantitatif dengan tata cara quasy eksperimental. Riset ini memakai 2 kelas, ialah kelas eksperimen yaitu media pembelajaran canva serta kelas kontrol menggunakan Microsoft power point. Hasil riset membuktikan angka pada umumnya pretes kelas eksperimen 42,4 serta kelas kontrol 41,2 hasil percobaan t didapat thitung = 0,311 serta ttabel= 1,708 karena thitung < ttabel maka kedua sampel mempunyai kemampuan awal yang sama. Nilai rata-rata postes kelas eksperimen ialah 76 dengan standar digresi 12,24 serta kelas kontrol ialah 67,6 dengan standar digresi 12,67. Hasil angka postes kelas penelitian serta kelas kontrol diuji coba dengan memakai percobaan t satu pihak serta didapat hasil 2,780> 1,708 yaitu thitung > ttabel pada taraf nyata 0,05 maka (Ha) diterima serta Ho ditolak, yang berarti terdapat akibat media canva terhadap hasil belajar mahasiswa pada materi pengaruh kebudayaan Barat/Asing di Indonesia.
DIRECTIONS FOR IMPROVING THE ORGANISATIONAL SYSTEM OF VALUE-BASED MANAGEMENT IN A HIGH-TECH COMPANY
Authors: Zakharchenko Vitaliy , Yermak Svitlana
Published: March 2023

The purpose of the article is to formulate directions for improving the organisational system of value-based management in a high-tech company. Methodology. The methods of analysis and synthesis, comparison and grouping, conceptualisation, strategic analysis and business process reengineering were the methodological basis of the research. Results. The conditions under which it is possible for Ukrainian high-tech enterprises to withstand competition, to survive, to develop, to be in the process of self-improvement, in a state of constant search for new organisational forms of functioning and technologies, new strategies of functioning, new types of products and new areas of application of products are defined. The methods of existence of high-tech companies are determined – the concept of survival and the concept of breakthrough. Within the framework of creation of modern organisational and technological systems three basic types of general business strategies are proposed – leadership, differentiation, focusing. For the modern practice of value-oriented management of innovative production from the point of view of intra-company management, the main characteristics are defined – functional, process, system, elemental. The organisational management of a high-tech enterprise when creating modern organisational and technological systems must take into account the following types of modernisation: technological, social, institutional, cultural. At the same time, possible ways of restructuring the enterprise are determined. The life activity of a high-tech enterprise is analysed in relation to its business processes and business functions. In general, the change in the goals and orientation of high-tech production is reflected in the content of the management concept and management structures, as the scope of cost analysis tasks related to the search for optimal conditions for the production and sale of goods, economic risk assessment and forecasting the behaviour of competitors is expanding. There is a need for infrastructural changes determined by the organisation and functioning of special units focused on the system of strategic planning and organisational support of decisions. Value/originality. A model of the organisation of intra-firm management in a high-tech enterprise is proposed by optimising the value-oriented management system of a high-tech enterprise, taking into account the complexity of the modern production system, its heterogeneity, the changeability of its elements, the structural diversity and the variety of links between them.
Using computer expert system to solve complications primarily due to low and excessive birth weights at delivery: Strategies to reviving the ageing and diminishing population
Authors: Felix Chukwuma Aguboshim  , Obinna Ogbonnia Otuu
Published: March 2023

The world now lives in an ageing society. Significant empirical evidence from the literature revealed that the world’s total fertility rate (TFR) estimate has experienced a declining trend from 5.30 in 1963 to 2.3 in 2020. The TFR for 2023 for the United States was 1.84, Canada 1.57, United Kingdom 1.63, Germany 1.58, Japan 1.39, China 1.45, Nigeria 4.57, India 2.07, Ghana 3.61, with Taiwan 1.09 and Niger 6.73 having the least and highest respectively. Non-adherence to God's childbearing principles, a female's age when she has her first child, educational opportunities, access to family planning, and government acts and policies affecting childbearing are all factors that may influence TFR. Despite the danger posed by the declining TFR trend, childbearing challenges and complications primarily due to low and excessive birth weights at delivery have heightened this danger. This study highlights strategies to leverage the provision of a computerized expert system (ES) solution to the problems of complications primarily due to low and excessive birth weights at delivery. A Knowledge-Based System (KBS) framework to simulate the problem-solving behavior of an expert in a narrow domain or discipline to unite the accumulated expertise of individual disciplines such as gynecology, ultrasonography, computer software design, and engineering was adopted. Fetal weight has been found to be a function of fetal head circumference (HC), femur length (FL), abdominal circumference (AC), and biparietal diameter (BPD) and predictable with a polynomial equation. Also, fetal age has been found to be a function of fetal weight and predictable by an equation. The equations for the determination of conception date and delivery dates were derived. The Expert System (ES) primarily estimates fetal parameters (fetal weight, fetal age or gestational age, conception date, and delivery date) in the first trimester using ultrasonographic fetal biometric data. The result of this study may eliminate or reduce the occurrence of potential complications associated with the birth of both small and excessively large fetuses, thereby contributing to reviving the world declining population.
Pengaruh Employee Engagement Dan Leader Member Exchange Terhadap Organizational Citizenship Behavior Dengan Mediasi Modal Sosial (Studi Pada Pegawai Yayasan XYZ)
Authors: Fitri Rizkika , Rozak Hasan Abdul
Published: March 2023

Background - The high level of competition in the field of educational services requires tertiary institutions to continue to improve the quality of human resources, in order to survive in the era of globalization. Organizations really need loyal and highly committed employees in order to survive and develop, therefore researchers are interested in studying the variables Employee Engagement, LMX and OCB.

Aim - This study aims to analyze the effect of Employee Engagement and Leader Member Exchange (LMX) on Organizational Citizenship Behavior (OCB) by mediating social capital on employees of the XYZ Foundation.

Design / Methodology / Approach – Population in this study were 177 employees of the XYZ Foundation, using a purposive proportional sampling technique, only using a sample of 109 employees. Research testing was carried out by testing validity, reliability, multiple regression analysis, t test, R2 test and moderation test using SPSS 22.

Findings – The results showed that: (1) Employee Engagement and LMX have a positive effect on Social Capital and OCB (2) Social Capital positive effect on OCB (3) Social capital mediates the effect of Employee Engagement on OCB, and (4) Social capital mediates the effect of LMX on OCB.

Conclusion - The empirical test results identify that the positive attitude resulting from Employee Engagement, LMX and social capital that exists in each employee will foster cooperation between fellow employees and superiors with the aim of personal success, other people and the organization.

Research Implication - This research is expected to make a positive contribution to further research, and to become a reference for organizations regarding the influence of employee engagement, LMX and mediation of social capital on OCB.

Limitation - The object of this research only took the XYZ Foundation with lecturers, teachers and employees as respondents who were still actively working at the XYZ Foundation.
Effect Of Spiritual Leadership And Psychological Contracts On Employee Job Satisfaction At Indonesian Islamic Bank (BSI) Bandung Branch
Authors: Suherman Usep , Ahman Eeng , Disman Disman
Published: March 2023

Background - Job satisfaction is a happy emotional state or positive emotion that comes from evaluating one's work or experience. With high job satisfaction will increase employee performance against the organization where they work. Lack of satisfaction with the company can lead to low employee performance. In this study related to job satisfaction of BSI Bandung Branch employees.

Aim - The aims of this study were to identify and analyze the influence of spiritual leadership and psychological contracts on employee job satisfaction at BSI Bandung Branch.

Design / Methodology / Approach – This study used descriptive and explanatory survey methods. The research was conducted on 90 BSI employees. Sampling was carried out using a saturated sampling technique. The data analysis technique used is Multiple Regression Analysis.

Findings – The results of this study show that spiritual leadership and psychological contracts partially or jointly have an impact on employee job satisfaction. Furthermore, a determinant value of 0.938 was obtained, this means that spiritual leadership and psychological contracts are able to explain employee job satisfaction of 93.8%. Meanwhile, 6.2% was caused by other factors.

Conclusion - The leadership of the BSI Bandung Branch must be able to implement spiritual leadership for employees and build a strong psychological contract for employees within the company. Job satisfaction needs to be improved again to improve organizational performance.

Research implication - To increase employee job satisfaction, it is necessary to pay attention to the attitudes and behavior of leadership shown by leaders to employees besides strengthening the psychological contract between employees and the organization.

Limitation - The scope of this research is limited to one particular company, so it does not reflect the situation of other institutions in the same study regarding spiritual leadership, psychological contract, job satisfaction
FINANCIAL PERFORMANCE OF TOURISM BUSINESSES UNDER THE INFLUENCE OF MEASURES RELATED TO COVID-19
Authors:   University of Economics in Bratislava, Department of Economics and Management, Faculty of Business Economy, Košice, Slovakia, LUKAC Jozef , GALLO Peter ,   University of Prešov, Faculty of Arts, Institute of Educology and Social Work, Prešov, Slovakia, BALOGOVA Beáta ,   University of Prešov, Faculty of Arts, Institute of Educology and Social Work, Prešov, Slovakia
Published: March 2023

We all know that the spread of the COVID-19 disease has brought significant restrictions for the whole world, which are also closely related to the business activities of companies. Due to the measures taken by the government of the Slovak Republic, some businesses were limited in the performance of their activities. In order to achieve the goal, in addition to general logical methods, we used hierarchical agglomerative cluster analysis. We chose the ward method as the clustering method. Ward's method of minimum variance is an agglomerative (merging) hierarchical method. Slovak businesses in the field of tourism, the most businesses contained cluster 3, which contained 16 businesses. This most numerous and dominant cluster has an average asset indicator value of 8546978 €. In Slovakia, as part of the aid to tourism enterprises at the government level, a call was launched within the framework of the scheme, during which it was possible to draw aid for the months of April to October 2020. This aid was supposed to cover the loss of 10% of their sales to entrepreneurs in the gastronomy and tourism industry.
UAV Image-Based Plan Drawing Method in Submerged Terrestrial Archaeological Settlements: The case of Kibotos
Authors: Gündüz Serkan
Published: March 2023

Documentation with drawing and photography is one of the most important stages in archaeological excavations and surveys. It takes a long time to draw walls by stone by stone during the excavations. Carrying out these studies on land that does not belong to human habitats, such as underwater, is an activity that requires extra effort, time, and experience. This article will examine the possibility of drawing the plans of the structures unearthed or detected in the archaeological underwater excavations and surface surveys in shallow waters with the help of aerial photographs in a shorter time and with less effort. The research results show that the photograph-based archaeological plan drawing is an excellent and suitable method for shallow water archaeological excavation and surveys. It reveals that it can save time and labour in surveys and rescue excavations where time is limited.
Teacher’s perception towards teaching and learning practice based on HOTs in mathematics
Authors: Sulaiman Norliyah , Mohd Ayub Ahmad Fauzi
Published: March 2023

Teaching and learning practice based on higher thinking order skills (HOTs) in mathematics is a critical approach to developing thinking skills among teachers and students in the classroom. It will help increase students’ performance and encourage acceptance and attitude. This study aims to know the teacher simulation on getting student responses and their reactions; to know the using of non-routine questions, the impact of applying and implication to the student’s mind development; and to understand the acceptances and attitudes of the student. This study was conducted using a qualitative approach, which involved a survey with an open-end questionnaire. A total of 72 mathematics teachers were made up of different categories of schools. The findings indicate that teachers tend to question and encourage ideas to simulated students on getting their response. Students tend to reflect on the teacher’s simulation verbally as a reaction. Using non-routine questions, the finding showed that teachers who were applied in their teaching practice agreed that it affects the student’s mind development. Teachers are also aware that thinking motivation and experiencing will be the implication of using non-routine questions in mathematics lessons. It also helps to develop students’ performance levels. Other teachers are aware that adaptability, attracting, and self-expression appear most as acceptance and attitude of students during instruction. In conclusion, for effective teaching and learning practice based on HOTs in mathematics lessons, bringing the real-life problem to the discussion in class, encouraging student’s cognitive develop and engage to their behavior.
Un algoritmo de búsqueda local iterada como solución al problema de la mochila
Authors: Labrada Nueva Yainier , Enriquez Urbano Juana , García Ojito Yadían
Published: March 2023

El problema de la mochila se clasifica como un problema de optimización combinatoria y, desde el punto de vista computacional, entra en la categoría de los problemas NP-completos [1]. En este artículo se soluciona el problema de la mochila aplicando un algoritmo de búsqueda local iterada en el contexto de la distribución de productos almacenados en bodegas y a su distribución en tiendas. En los resultados obtenidos se observa la convergencia del algoritmo implementado.
Pemanfaatan Etnomatematika Untuk Meningkatkan Aktivitas Dan Hasil Belajar Siswa Kelas IV SDN 1 Senggrong
Authors: Zulfa Oktavia nurhana , Wicaksono Anggit Grahito , Prihastari Ema Butsi
Published: March 2023

This research was conducted at SD Negeri 1 Senggrong Boyolali. The subjects in this study were grade IV students. This research is included in Classroom Action Research (PTK) which is carried out in two cycles, each cycle consisting of 4 meetings. Interviews, observation, documentation are the techniques used in data collection. After all the data has been collected, the researcher processes the data using a comparative descriptive analysis technique. Ethnomathematics is proven to be able to increase the activity and learning outcomes of mathematics, it can be seen from the pre-cycle data that only 40% achieve a score of 75 as the Minimum Completeness Criteria (KKM). After the implementation of cycle 1, students who passed the KKM were 60% and the implementation of cycle 2 succeeded in increasing the percentage of student completeness to 80%. Referring to the results obtained, it can be concluded that at SD Negeri 1 Senggrong Boyolali Semester II for the 2021/2022 school year, the use of ethnomathematics-based picture card teaching materials is proven to be able to increase the activity and learning outcomes of class IV students.
The Influence of Psychological Capital, Certification Status and Work Resources on Teachers Performance
Authors: Hudain Muh Adnan , Khasanah Fitria , Pramono Susatyo Adhi , Haryanto Dede , Kamaruddin Ilham
Published: March 2023

This study's objective is to ascertain how self-efficacy, optimism, hope, and social support affect all aspects of a teacher's profession, including their autonomy, connection with superiors, performance evaluations, and certification status. The sample for this study included 859 high school teachers. With a non-probability selection process, 230 teachers were chosen. Use confirmatory factor analysis (CFA) techniques to assess the accuracy of measurement tools. Using multiple regression to examine research data. The results of the study show that numerous elements, such as self-efficacy, optimism, hope, resilience, social support, the nature of a teacher's connection with superiors, autonomy, performance assessment, and teacher certification status, have a significant impact on all of a teacher's work. The results of the study show that all independent factors can explain 49% of the variance in the overall amount of work, while variables not included in the study have an impact on the remaining 51%. According to the results of the hypothesis testing, hope, optimism, and self-efficacy all significantly affect how well an individual performs at work.
Pengaruh Tingkat Emosi, Kecukupan Gizi dan Kebiasaan Hidup Ibu Hamil terhadap Perkembangan Janin
Authors: M Nuramalia. , Grafita Nuranggun , Makmur Madina , Mayora Meldini Indri
Published: March 2023

The purpose of this study was to determine the effect of emotional level, nutritional adequacy and living habits of pregnant women on fetal development. The type of research used is expos facto research. The Facto Exposure Method is a research method for examining the cause-effect relationship of an event. From these causal linkages, new possibilities will be found that can be used as indicators in the research process. Based on the research results show that the emotional level of the mother during pregnancy can also affect the development of the fetus until the birth process, because this can cause an irregular supply of fetal oxygen, which can cause problems in the fetus. the emotional level causes irregular contractions so that the birth process will be difficult. An imbalance in nutrient consumption, especially a lack of intake of one or more nutrients during pregnancy can increase the risk of complications in pregnant women such as chronic energy deficiency (CED), anemia, difficult and long labor and susceptibility to infectious diseases (Ernawati, 2012). Meanwhile, the habits of pregnant women can affect the fetus based on the level of activity carried out, healthy living habits will have a positive impact on fetal development. However, bad habits and anxiety will affect the psychology and development of the fetus.
Teori Belajar Behaviorisme Ivan Pavlov dan Implikasinya dalam Pembelajaran Bahasa Arab Siswa Madrasah Tsanawiyah Negeri
Authors: Nafila Ariane , Utami Dewi , Mardani Dadan
Published: March 2023

This study aims to find out the implications of Ivan Pavlov's behaviorism learning theory in learning Arabic for class VIII students of Madrasah Tsanawiyah Negeri (MTsN) Sukabumi City and its advantages and disadvantages. The method used in this study is a qualitative approach with observation techniques. This study also used interview techniques for Arabic teacher in class VIII MTs Negeri Sukabumi City and to 12 students of MTs Negeri Kota Sukabumi who came from the 4 classes. The results showed that there are many behaviors in Arabic language learning for class VIII MTs Negeri Sukabumi City students that are relevant to Ivan Pavlov's concept of behaviorism learning theory, namely to make students learn, teacher provides certain conditions. The advantage of this learning theory is suitable to be applied to Arabic language learning for class VIII students of MTs Negeri Sukabumi City, because most of the students show the expected response when the teacher often applies repetition and habituation related to the material being studied. The disadvantage lies in the hours of study that affect the response given by the students. Students who learn Arabic in the morning tend to be quick in responding to the stimulus provided by the teacher.
Open and collaborative innovation for the social construction of learning: analysis from the design of an xMOOC
Authors: Minga-Vallejo Ruth-Elizabeth , Ramirez-Montoya Maria-Soledad , Rodríguez-Conde María-José
Published: March 2023

 Technological advances have promoted digital processes in education that expand training possibilities, such as xMOOCs (eXtended Massive Open Online Courses). Considering the design of the xMOOC, the purpose of the study was to analyze the social construction of learning in the light of open and collaborative innovation.  
Serbian Military Commander General Mladić
Authors:   Institute of Slavic Studies, Russian Academy of Sciences, Guskova Elena
Published: March 2023

The author studies the Serbian Colonel-General Ratko Mladić, who headed the armed forces of the Republika Srpska from 1992-1995. For the Serbs, he was and remains a great strategist and architect of all Serbian victories in Bosnia; for the world community, an unyielding, disobedient, and rude aggressor; and for Muslims and Croats, a dangerous and insidious enemy. The researcher follows his studies and service in the Socialist Federal Republic of Yugoslavia, his family, his attitude to the collapse of Yugoslavia, and the creation of the RS Army. From 2006, General Mladić went into hiding from the official authorities, who had begun a serious hunt for the general. The general was eventually arrested in May 2011.
Franjo Tuđman and the Problems of the Modern Croatia
Authors:   Institute of Slavic Studies, Russian Academy of Sciences, Pivovarenko Alexander
Published: March 2023

The author examines the main points of the biography of Franjo Tuđman as the most prominent politician of modern Croatia. Tuđman's biography has a wide scope: a Yugoslav partisan, a high-ranking military officer, a political party official, an academician, a dissident and, finally, a politician. Although Tuđman has been the subject of many studies in the Croatian and English-language literature since the beginning of the 2000s, some pages of his biography still remain in the shadows. Despite the fact that in Croatia official apologetics have been expressed on the role and place of Tuđman in the breakup of Yugoslavia and the formation of the political system in Croatia (which still broadly exists), there are also other views that give room for greater skepticism about the developments in the 1990s. The author provides a brief overview of this sensitive issue.
Andrey Lukanov. The Communist Who Started the Transition to Democracy in Bulgaria
Authors:   Sofia University St. Kliment Ohridski, Bayeva Iskra
Published: March 2023

The author presents a political portrait of Andrey Lukanov, one of the brightest personalities of the period from the end of socialism to the beginning of the transition to democracy in Bulgaria. His family connections and professional training made him part of a privileged group in socialist Bulgaria, the nomenklatura . Lukanov's career in socialist Bulgaria skyrocketed him from adviser to minister and then deputy prime minister, becoming a leading figure among the BCP technocrats. Close ties with the Soviet Union and Mikhail Gorbachev provided Lukanov with an opportunity to take an active part in the changes in Bulgaria when applying the Soviet “perestroika” model and, above all, to prepare for the overthrow of longtime leader Todor Zhivkov. Lukanov played a key role in the changes that began on 10 November 1989, but his idea of transforming Soviet-style state socialism into the Western-style democratic socialism failed. He briefly led two governments in 1990, but a wave of political change soon overthrew him. In the following years, Lukanov devoted his efforts to the creation of new economic groups in a market (capitalist) economy, until, in early October 1996, he was shot dead.
Pedagoški rad sestara Broch
Authors: Boršić Luka , Skuhala Karasman Ivana
Published: March 2023

Milka Broch u Pakracu je 1902. godine vodila privatnu Višu djevojačku školu koja se 1913. godine preselila u Zagreb gdje se nazvala Privatna viša djevojačka škola. Godine 1925. škola je postala Privatna (mješovita) niža realna gimnazija, a 1927. preimenovana je u Privatnu mješovitu gimnaziju »Udruženja za individualni uzgoj i nastavu mladeži u Zagrebu pod vodstvom dr. Ade Broch i sestara«. Školi je prelaskom u Zagreb bio pridružen internat, prvo za židovske djevojke, potom za dječake. Ravnateljica tih škola bila je od 1902. do 1928. godine Milka Broch, a nakon toga djelomično Adam Rubetić i Ada Broch. U ovom tekstu dajemo kratak pregled života i karijera triju sestara Broch koliko je relevantno za njihovu pedagošku djelatnost, a potom opisujemo kako je djelovala njihova privatna gimnazija u razdoblju između 1925. i 1940. godine kad joj je naprasno bilo oduzeto pravo javnosti.
APTx: better activation function than MISH, SWISH, and ReLU's variants used in deep learning
Authors: Kumar Ravin
Published: March 2023

Activation Functions introduce non-linearity in the deep neural networks. This nonlinearity helps the neural networks learn faster and efficiently from the dataset. In deep learning, many activation functions are developed and used based on the type of problem statement. ReLU’s variants, SWISH, and MISH are goto activation functions. MISH function is considered having similar or even better performance than SWISH, and much better than ReLU. In this paper, we propose an activation function named APTx which behaves similar to MISH, but requires lesser mathematical operations to compute. The lesser computational requirements of APTx does speed up the model training, and thus also reduces the hardware requirement for the deep learning model
Differential expression of DCUN1D5 in colorectal cancer.
Authors: Mamoor Shahan
Published: March 2023

Cancer is a leading cause of death and colorectal cancer is among the most lethal cancers (1, 2). We mined published and public microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with colorectal cancer (CRC). We found significant differential expression of the gene encoding defective in cullin neddylation 1 domain-containing 5, DCUN1D5, when comparing colorectal tumors to the tissue of origin, the colon. DCUN1D5 mRNA was present at significantly higher quantities in tumors of the colon as compared to normal colorectal tissue. DCUN1D5 expression changes may be important for the initiation or progression of human CRC.
Differential expression of FUCA1 in colorectal cancer.
Authors: Mamoor Shahan
Published: March 2023

Cancer is a leading cause of death and colorectal cancer is among the most lethal cancers (1, 2). We mined published and public microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with colorectal cancer (CRC). We found significant differential expression of the gene encoding fucosidase, alpha-L- 1, tissue, FUCA1, when comparing colorectal tumors to the tissue of origin, the colon. FUCA1 mRNA was present at significantly lower quantities in tumors of the colon as compared to normal colorectal tissue. Analysis of human survival data revealed that expression of FUCA1 in rectal tumors was correlated with recurrence-free survival in patients with rectal cancer. FUCA1 expression changes may be important for the initiation or progression of human CRC.
Differential expression of SIM2 in colorectal cancer.
Authors: Mamoor Shahan
Published: March 2023

Cancer is a leading cause of death and colorectal cancer is among the most lethal cancers (1, 2). We mined published microarray datasets (3, 4) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with colorectal cancer (CRC). We found significant differential expression of the gene encoding single-minded family bHLH transcription factor 2, SIM2, when comparing colorectal tumors to the tissue of origin, the colon. SIM2 mRNA was present at significantly higher quantities in tumors of the colon as compared to normal colorectal tissue. Analysis of human survival data revealed that expression of SIM2 in rectal tumors was correlated with overall survival in patients with rectal cancer. SIM2 expression changes may be important for the initiation or progression of human CRC.
The more the merrier? A three-level meta-analysis of the relationship between working memory and category learning
Authors: WANG Ziyang , Yu Delin
Published: March 2023

Currently, studies on working memory and category learning have reported correlation coefficients ranging from -0.324 to 0.573, with widely varying results. This study used meta-analysis techniques to integrate eight studies with 58 effect sizes and 1618 subjects. The results showed that there was a significant positive correlation between working memory and category learning. There were no significant moderating effects for type of category learning, gender, or age. The facilitation effect of working memory was the same for both rule-based category learning and information integration category learning. There was a cross-gender and cross-age convergence in the facilitation effect of working memory on category learning.
QuietQuitting ongoing analyses by studies in the pre-registration
Authors: Patel Pankaj , Guedes Maria João , Bachrach Daniel , Cho Younsung
Published: March 2023

This project is associated results and ongoing analysis of pre-registration: https://doi.org/10.17605/OSF.IO/KTPAB
Relationship between cerebrovascular diseases and human leukocyte antigen subgroups
Authors: ÇINKIR Ufuk , TEKE Eylem , METE Ergun
Published: March 2023

Purpose: Ischemic stroke is classified as large artery atherosclerosis, small vessel occlusion (lacunar infarcts), ischemic stroke due to other identified causes, and cryptogenic. The human leukocyte antigen (HLA) complex is a group of genes on chromosome six in humans responsible for encoding cell-surface proteins that regulate the immune system. In this study, HLA’s roles in the pathophysiology of ischemic stroke, especially the lacunar subgroup, are investigated, and their potential mechanisms are presented.

Materials and methods: This study consisted of 49 patients with ischemic stroke and 50 healthy participants. HLA-A, HLA-B, HLA-C, HLA-DQB, and HLA-DRB subgroup genomes were assessed.

Results: A statistically significant difference in the presence of HLA-A, HLA-B, HLA-C, HLA-DQB, and HLA-DRB subgroups was found between the control and patient groups. The presence of HLA-A*02, HLA-A*30, HLA-B*08, HLA-B*15, and HLA-DQB*06 genomes was higher in the patient group than in the control group (p≤0.05). Nevertheless, HLA-DQB*03 and HLA-DRB*11 genomes were found more in the control group than the patient group (p≤0.05)

Conclusion: The results of this study pioneered in scrutinizing HLA alleles in small vascular disease (SVD). HLA-A*01, HLA-A*30, HLA-B*08, HLA-B*15, HLA-DQB*06, HLA-DQB*03 and HLA-DRB*11 are associated with HLA alleles of stroke patients with small vessel occlusion. We attempted to provide objective evidence for whether HLA genomes could act as a discriminative factor between SVD patients and control groups, which might hold considerable promise for future therapies.
Factors Influencing Effective Communication between Stakeholder Groups during DVM Work-Based Learning Program in Bangladesh
Authors: Mohsin Md. Abu Shoieb , Hoque Md. Ahasanul , Sattar Abdullah Al , Baillie Sarah
Published: March 2023

This study aimed to review the existing communication systems between the universities, placement providers, and students during the DVM final year work-based learning (WBL) program in Bangladesh. The intention was to identify what factors impact the effectiveness of the communication system and to explore ways to enhance communication to better support the program. A questionnaire was used to collect details about the WBL program and the communication systems from all universities in Bangladesh. The questionnaire was completed on paper at a meeting of the National Veterinary Dean Council and online with a member of each university's WBL coordination team. A summary of the current WBL programs in Bangladesh was produced. Focus group discussions were used to collect more detailed information about the communication systems and were held via Zoom with recent graduates ( n = 16) and placement providers ( n = 7). Effective means of communication between all stakeholders were identified as an initial letter, phone calls, and spot visits by teachers. However, the frequency of formal communication before and during placements was variable, and the ways of providing feedback on the communication systems were insufficient. These issues sometimes undermined the student learning experience. Suggestions for improvements included increased resourcing, greater use of online communication systems, and a national committee to oversee WBL. Other ways to motivate placement providers included a better honorarium and continuing education courses. The results suggest that existing communication systems for veterinary WBL in Bangladesh are not completely satisfactory. Measures are needed to improve communication to optimize the student learning experience and capitalize on the many benefits of the WBL program for all stakeholders.
Effects of Composition, Processing, and Structure on Properties of Engineering Plastics
Authors: Perez Jose M. , Hinkley Jeffrey
Published: March 2023

This article provides practical information and data on property development in engineering plastics. It discusses the effects of composition on submolecular and higher-order structure and the influence of plasticizers, additives, and blowing agents. It examines stress-strain curves corresponding to soft-and-weak, soft-and-tough, hard-and-brittle, and hard-and-tough plastics and temperature-modulus plots representative of polymers with different degrees of crystallinity, cross-linking, and polarity. It explains how viscosity varies with shear rate in polymer melts and how processes align with various regions of the viscosity curve. It discusses the concept of shear sensitivity, the nature of viscoelastic properties, and the electrical, chemical, and optical properties of different plastics. It also reviews plastic processing operations, including extrusion, injection molding, and thermoforming, and addresses related considerations such as melt viscosity and melt strength, crystallization, orientation, die swell, melt fracture, shrinkage, molded-in stress, and polymer degradation.
Navigating the Plastic Material Selection Process
Authors: Gramann Paul J.
Published: March 2023

There are many reasons why plastic materials should not be considered for an application. It is the responsibility of the design/materials engineer to recognize when the expected demands are outside of what the plastic can provide during the expected life-time of the product. This article reviews the numerous considerations that are equally important to help ensure that part failure does not occur. It provides a quick review of thermoplastic and thermoset plastics. The article focuses primarily on thermoset materials that at room temperature are below their glass transition temperature. It describes the motivation for material selection and the goal of the material selection process. The use of material datasheets for material selection as well as the processes involved in plastic material selection and post material selection is also covered.
Thermal Stresses and Physical Aging of Plastics
Authors: Duvall Donald E.
Published: March 2023

Engineering plastics, as a general class of materials, are prone to the development of internal stresses which arise during processing or during servicing when parts are exposed to environments that impose deformation and/or temperature extremes. Thermal stresses are largely a consequence of high coefficients of thermal expansion and low thermal diffusivities. Although time-consuming techniques can be used to analyze thermal stresses, several useful qualitative tests are described in this article. The classification of internal stresses in plastic parts is covered. The article describes the effects of low thermal diffusivity and high thermal expansion properties, and the variation of mechanical properties with temperature. It discusses the combined effects of thermal stresses and orientation that result from processing conditions. The article also describes the effect of aging on properties of plastics. It explains the use of high-modulus graphite fibers in amorphous polymers.
Fundamentals of Polymer Additives
Authors: Patel Jigneshkumar P. , Schneider Yanika , Sankarasubramanian Malavarayan , Jayaram Vidya
Published: March 2023

Polymer materials are key building blocks of the modern world, commonly used in packaging, automobiles, building materials, electronics, telecommunications, and many other industries. These commercial applications of polymeric materials would not be possible without the use of additives. This article is divided into five sections: mechanical property modifiers, physical property modifiers, biological function modifiers, processing aids, and colorants. It describes three classes of additives that are used to inhibit biological activity, six classes of mechanical property modifiers, three classes of physical property modifiers, and two classes of both colorants and processing aids.
Viscoelasticity of Plastics
Authors: Olig Scott M.
Published: March 2023

This article describes the viscoelastic behavior of plastics in their solid state only, from the standpoint of the material deforming without fracturing. The consequences of viscoelasticity on the mechanical properties of plastics are described, especially in terms of time-dependencies, as well as the dependence of the viscoelastic character of a plastic on chemical, physical, and compositional variables. By examining the viscoelastic behavior of plastics, the information obtained are then applied in situations in which it may be important to anticipate the long-term properties of a material. This includes assessing the extent of stress decay in materials that are pre-stressed, the noise and vibration transmission characteristics of a material, the amount of heat build-up in a material subjected to cyclic deformation, and the extent a material can recover from any prior deformation. Several qualitative graphs are presented, which highlights the possible differences in the viscoelastic behavior that can exist among plastics.
Surface Examination and Analysis of Plastics
Authors: Ensha Sya , West Paul , Attavar Sachin
Published: March 2023

This article discusses the operating principles, advantages, and limitations of scanning electron microscopy, atomic force microscopy, x-ray photoelectron spectroscopy, and secondary ion mass spectroscopy that are used to analyze the surface chemistry of plastics.
Application of Electromagnetic Field to Produce Flattened Cereals from Emmer Wheat Grains
Authors: Hospodarenko Hrygorii , Liubych Vitalii , Novikov Volodymyr , Leshchenko Ivan , Oliinyk Olena
Published: March 2023

The study presents the results of the radiation of hulled emmer wheat grains during the production of flattened cereals. Emmer wheat grains (dehulling index 13–15 %) after moistening were exposed to the radiation in the microwave oven for 20–180 s. Flattened cereals were divided into the premium and first-grade quality, shredded cereals and middlings. The study focused on the changes in the output and culinary properties of flattened cereals depending on the duration of radiation, level of humidification and cultivar properties. Application of the electromagnetic field had a strong influence on the output of flattened cereals. Moistening had a positive influence on the output of flattened cereals of the premium grade. The total output of cereal products after flattening of cereal from emmer wheat № 1 of Holikvska variety without hydrothermal treatment varied from 85.5 to 97.3 % depending on the duration of treatment in a microwave oven. Moistening of cereals by 0.5 % didn’t raise the total output of cereals as it was expected. The output of flattened cereals varied depending on the cultivar. The highest output of flattened cereals (79.2 %) was obtained from emmer wheat of Holikovska variety. To obtain the highest output of flattened cereals of the premium grade should be exposed to the radiation for 80–120 s depending on the cultivar/ line. The increase in time of radiation in the microwave (>120 s) leads to the considerable crushing of cereals after flattening. The cooking time of flattened cereals decreases as the time of treatment in the microwave oven increases. Only cultivar properties influence the organoleptic parameters (color, flavor). Radiation of cereals № 1 from emmer wheat Holikovska for 80–100 s without moistening provides a high output of flattened cereals of the premium grade with excellent organoleptic parameters.
Вплив меланіну, отриманого з дріжжеподібних грибів Nadsoniella nigra spр. X1 (о. Галіндез, Антарктика) на проліферацію, адгезію та апоптоз пухлинних клітин епітеліального походження
Authors: Yakovlev P. G. , Garmanchuk L. V. , Falalyeyeva T. M. , Shelest D. V. , Bilyuk A. A. , Nikulina V. V. , Skachkova O. V. , Beregova T. V. , Ostapchenko L. I.
Published: March 2023

Меланін – представник родини поліфенолів, який значно поширений у рослинах. Він має властивість зменшувати проліферацію клітин та метастазування. Крім того, є дані про його здатність зупиняти клітинний цикл, запускати апоптоз, пошкоджувати ДНК. У дослідженні ми показали, що на культури клітин HeLa та MCF-7 меланін виявляє цитотоксичний та цитостатичний ефекти і змінює ядерно-цитоплазматичне співвідношення, що може бути пов'язане з епітеліально- мезенхімальним переходом. також інкубація HeLa з меланіном спричиняла зниження апоптозного індексу, пов'язане з інвазивними характеристиками клітин карциноми.
Substantiation of relaxings plintused on patients with the parafunction of chewing muscles
Authors: Kostiuk T. , Chrol N. , Shevchuk V. , Shpak D.
Published: March 2023

The researchconducted by us has enabled us to analyze the influence of relaxingsplintson the chewing muscles’ condition of patients with dualfunction and to study the dynamics of the changes EMG-activity of their chewing muscles.
Брадикардия, вызванная нитроглицерином
Authors: Vazhnichaya E. M. , Kolot E. G.
Published: March 2023

Описан случай сублингвального приёма нитроглицерина у практически здорового мужчины молодого возраста, который сопровождался кратковременным уменьшением частоты сердечных сокращений и умеренным снижением артериального давления с полной нормализацией этих показателей в течение 7 мин. Проанализированы данные литературы о подобном феномене, его встречаемости в практике.
Clinical characteristic of juvenile rheumatoid arthritis debut and course
Authors: Konyshevskaya A. A. , Vaizer N. V. , Shelestova L. P.
Published: March 2023

The article is devoted to juvenile rheumatoid arthritis – one of the most common rheumatic diseases with children. High activity and aggressive course of juvenile rheumatoid arthritis are common with children with systemic and polyarticular disease variants debut. The article presents case studies of children with systemic and polyarticular variants debut of juvenile rheumatoid arthritis.
Healthcare Educational Technologies as a Means of Optimizing Students’ Learning
Authors: Borisenko L. L. , Zhuravska L. M. , Mendrukh І. M.
Published: March 2023

According to the research objective the article discloses the major applications of healthcare educational technologies in contemporary system of higher education. These technologies are considered as a means of optimizing students’ learning on the basis of ergonomic approach which prevents health damaging while creating a system of favorable conditions for the health of all participants of this process. The methodological base for the research is the theory of educational process optimization (Yu. Babansky) and the theory of efficient education management (V. Bespalko, T. Ilyina, N. Talyzina). The results of the research reveal the following reasons for the appearance of negative functional states of the students: considerable overload of students with different types of learning activity and increasing volume of information to be mastered by them that cause anxiety, worries, tiredness and lower academic performance of students. To optimize students’ learning certain measures regarding the creation of suitable organizational as well as social and psychological conditions of learning that meet ergonomic requirements are offered.
Psychophysiological mechanism of neurotic disorder formation
Authors: Mazyar О. V.
Published: March 2023

The aim of paper is to specify features of the psychophysiological mechanism of human neurotic disorder formation. The analysis of specific cases of neurotic disorder (on the example of the literary character behavior) is used as main methodology. The paper specify that neurotic disorder is the result of ultra paradoxical stage inertia of parabiosis, which undergoes three phases of changes in the formation of diplasty (binary emotional structure). The limitation of the chosen methodology is the impossibility to record the dynamics of nerve processes using objective methods (apparatus); lack of statistical confirmation of the results. Practical value is in predicting the dynamics of neurotic disorders and determination the ways of leveling personal problems. Three phases of the ultraparadoxical stage of the nervous process are identified, which explain its initial inertia and fixation.