bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Media Sosial Sebagai Alat Promosi Terhadap Minat Peserta Didik di SMA Batik Surakarta
Authors: Qarlina Cherly Dwi , Purwanto  , Fitri Wulandari
Published: August 2023

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Media sosial kini menjadi gaya hidup yang tak terpisahkan bagi generasi milenial. Selain sebagai wadah interaksi sosial, media sosial juga memainkan peran penting sebagai alat promosi bagi organisasi, lembaga, dan perusahaan. Bahkan, sekolah dan lembaga pendidikan pun tak ketinggalan memanfaatkan media sosial untuk mempromosikan diri, menarik minat calon siswa, dan memberikan informasi kepada masyarakat. Oleh karena itu, sebuah penelitian dilakukan di SMA Batik Surakarta untuk menggali sejauh mana pengaruh media sosial sebagai alat promosi terhadap minat peserta didik. Dalam penelitian ini, siswa dan siswi SMA Batik Surakarta dijadikan responden dengan jumlah sampel sebanyak 93 yang berasal dari 4 jurusan. Hasil penelitian menunjukkan bahwa penggunaan media sosial sebagai alat promosi memiliki pengaruh yang signifikan terhadap minat peserta didik, dengan kontribusi sebesar 35,2%. Namun, ditemukan juga bahwa faktor-faktor lain yang tidak termasuk dalam penelitian memiliki pengaruh sebesar 64,8% terhadap minat peserta didik. Melalui analisis menggunakan SPSS 26.0, ditemukan bahwa nilai T sebesar 6.019, melebihi nilai T tabel 1.662 pada tingkat signifikansi 5%. Hal ini mengindikasikan bahwa media sosial sebagai alat promosi memiliki pengaruh positif dan signifikan terhadap minat peserta didik di SMA Batik Surakarta. Dengan demikian, hipotesis alternatif diterima dan hipotesis nol ditolak, menyatakan bahwa pengaruh media sosial sebagai alat promosi terhadap minat peserta didik terbukti signifikan.
Nda-nwendaaganag (All My Relations)
Authors: Shawanda Amy
Published: August 2023

There is a scholarly gap regarding how to cite Nda-nwendaaganag (All My Relations) in academic writing. Nda-nwendaaganag encompasses both the animate and inanimate beings referred to as ‘All My Relations’. I have devised several ways for Indigenous scholars to refer to "All My Relations," because they are our collaborators, co-creators, and idea generators. The purpose is we acknowledge, honor, respect, celebrate, and to express our gratitude to Nda-nwendaaganag as contributors to our written work. In order to create the various methods for Nda-nwendaaganag, I gained motivation from the Baawaajige (Dream) Methods for citation inspiration (Shawanda, 2020). It was considering the critical moments in our time to record the source of knowledge, sacred space, and within seasons to capture when "All My Relations" shared and guided our knowledge. I categorize citation sources from an Anishinaabk worldview on the animate or inanimate. They are distinct in terms of how the information should be recorded for citation purposes. This includes things like the time of day/season, specific locations, and the geography of the generated theme, message, or idea. This will provide Indigenous students, scholars, and researchers to further decolonize settler knowledge systems. I hope that this resource will be useful to students, scholars, and researchers. I understand that it will not be accepted as valid citation practice within western sources, but it is a first step toward honouring and acknowledging Nda-nwendaaganag.
La vulneración del derecho a la defensa, frente al mal uso de las medidas de protección por parte de la víctima en violencia contra las mujeres
Authors: Carangui Vásquez José Miguel , Torres Wilchez Marcelo
Published: August 2023

Introducción: el presente trabajo investigativo analizó la vulneración del Derecho a la defensa con relación al mal uso de las medidas de protección específicamente el inadecuado uso de las Boletas de Auxilio por parte de la supuesta víctima en violencia contra las mujeres. Objetivos: demostrar que es indispensable justificar los hechos que se plantean en cada denuncia antes de otorgar una boleta de auxilio.  Metodología: este aporte académico se desarrolló en base a un enfoque cualitativo con la recolección de información, mismos que se tomaron de códigos, resoluciones, artículos jurídicos y estudios sobre la violencia contra la mujer o miembros del núcleo familiar. Además, en este estudio se empleó los métodos analítico-sintético, método inductivo-deductivo, así como el histórico-lógico, el dogmático, y la técnica de investigación denominada revisión bibliográfica. Conclusiones: la conclusión que arrojó este trabajo justificó que con el mal uso de las boletas de auxilio se vulnera el derecho a la defensa del denunciado, con la obtención inmediata de las boletas de auxilio se protege los derechos de la supuesta víctima, pero se deja en indefensión al presunto infractor. Resultados: las boletas de auxilio se entregan de manera inmediata a la persona denunciante, sin antes hacer una investigación previa y sin contar con elementos de convicción suficientes. Actualmente, la mujer enfrenta una lucha constante contra la violencia intrafamiliar, sin embargo es necesario denotar que existen sanciones que podrían aplicarse a aquellas personas que violentan a mujeres, por ejemplo: el abuso en el uso indiscriminado de las medidas de protección, situación que provoca que la plétora de medidas de protección rompa o desquebraje la presunción de inocencia de la persona agresora. Área de estudio general: Derecho. Área de estudio específica: Derecho Penal y Litigación Oral.
Diabetes mellitus emergence in Covid-19 Pandemic
Authors: Banik Debabrata
Published: August 2023

Abstract not aavailable
JBSA 2021; 34 (2) : 1-2
Emergence Delirium in Paediatric Anaesthesia
Authors: Maruf Abdullah Al , Kamal Md Mustafa , Hassan Mehdi
Published: August 2023

Emergence delirium(ED) in children is a well-documented clinical phenomenon with incidence rangingfrom 25 to 80%. It is characterized by confusion, mental irritability, disorientation, inconsolable crying,and thrashing. No single factor can identified as the cause of postoperative agitation, which shouldtherefore be considered a syndrome made up of biological, pharmacological, psychological and socialcomponents. Possible causes and risk factors include child’s personality, inhalation anaesthetics,surgery of head and neck, rapid awakening and pain. Many scales have been proposed to evaluate theincidence and severity of ED and a variety of scales are used in clinical practice and for researchpurposes in children. Preventive measures include the co-administration of propofol, midazolam, orfentanyl, but the risks associated with their use must be weighed against the self-limiting nature of ED.Once ED is established, the most common interventions are pharmacological. Treatment options areclam environment in recovery and with agents having sedative and analgesic effect,such as propofol,fentanyl, ketamine andalpha-2 receptor agonists (clonidine and dexmedetomidine). ED may increasethe incidence of new-onset postoperative maladaptive behavior changes such as general anxiety,night-time crying, bed wetting, general anxiety and loss of appetite for up to 14 days after surgery. Astandard diagnostic, preventable and treatable guideline should be required for adverse outcomes in thepaediatric populations.
JBSA 2021; 34 (2) : 16-23
THE EFFECT OF AIR FUEL RATIO (AFR) ON EFFICIENCY OF GAS TURBINE ON UNIT 2 OF GAS POWER PLANT PT. PLN (PERSERO) KRAMASAN PALEMBANG-SOUTH SUMATERA PROVINCE
Authors: Angky Puspawan , Sulthan Rifki , Suandi Agus , Witanto Yovan
Published: August 2023

Gas turbine efficiency is an indicator to determine the performance of a generator. The greater the efficiency value of the gas turbine in a generator, the better the performance of the generator. One of the things that affect the value of the efficiency of a gas turbine is the air fuel ratio. Air Fuel Ratio (AFR) is the ratio of the amount of air and fuel in the combustion process in units of mass or volume. Air fuel ratio is a factor that affects the perfection of the combustion process in the combustion chamber. In the graphic image it can be seen that the lowest AFR values ​​are on July 3 and 4 2022, when the gas turbine produces a loading of 20900 kW and 20100 kW with an AFR value of 39.76 unitless each. Whereas the highest AFR value is on June 28 2022 when the gas turbine produces a loading of 20780 kW with an AFR value of 40.68 unitless. The highest gas turbine efficiency value is on June 30, 2022, at a loading of 20,650 kW with a gas turbine efficiency of 83.3%. The lowest efficiency value is on July 2, 2022, at a load of 20,800 kW with a gas turbine efficiency of 81.05%. From the results of existing data processing and graphs, it can be seen that the value of the air fuel ratio and the efficiency of the gas turbine are inversely proportional, which means that when the value of the air fuel ratio decreases, the value of the efficiency of the gas turbine tends to increase. However, there are some deviations when the value of the air fuel ratio decreases, the efficiency of the gas turbine also decreases. Therefore it can be concluded that the value of the air fuel ratio affects the value of the efficiency of the gas turbine, however, the value of the air fuel ratio is not the only factor that affects the value of the efficiency of the gas turbine.
Application of the Make a Match Model in Learning Arabic Mufradat
Authors: Aini Sekar Dwi Nur , Nurfuadi Nurfuadi
Published: August 2023

Inlearning Arabic there are four abilities that must be learned and mastered by students, namely the ability to listen, speak, read and write. To master these four skills, one of the efforts that must be taken is to improve the acquisition  of mufradat or Arabic vocabulary, because it is very helpful for the learning results of the four Arabic skills.This study aims to find out and analyze how the application of  the Make A Match model  in learning  Arabic mufradat at MTs Muhammadiyah 09 Purbalingga.        This research is a type of field research that is qualitative descriptive with data collection techniques through observation, interviews, and documentation. The results of this study show that mufrodat learning  at MTs Muhammadiyah 09 Purbalingga, teachers conduct learning in three stages, namely the preparation, implementation and evaluation stages. Then in the implementation of  mufradat learning the  teacher uses  the Make a Match model  to help students understand and memorize  the mufradat given. By using this model, it creates  a pleasant learning atmosphere and makes students become more active when participating in learning activities..
The Effect of Social Media on Student Learning Achievement at SD Negeri Daya 1 Makassar
Authors: Nurhidayah Nurhidayah , Alannasir Wahyulla , Fitri Riskal
Published: August 2023

This study aims to describe the description of the learning achievement of students at SD Negeri Daya 1 Makassar, to explain how much influence social media has on the learning achievement of students at SD Negeri Daya 1 Makassar and to find out the factors that influence student achievement at SD Negeri Makassar Power 1. The type of research used in this study used total sampling so that as many as 27 students were obtained from the total number of students. The instrument used is in the form of a social media questionnaire and to find out the learning achievement of students is in the form of end-of-semester scores. Based on the results of the research, the hypothesis test found that there was a significant influence of social media on the learning achievement of SD Negeri Daya 1 Makassar students. This can be seen from the t-value of social media, namely -2.154 > 1.708 and a significant level of 0.041 <0.05.
Development of Textbooks for Sports Physiology Course in the Department of Physical Education and Health, State University of Malang
Authors: Victoria Andif , Mustafa Pinton Setya , Winarno M.E.
Published: August 2023

The aim of this research is to created a product in the form of a sports physiology textbook for physical education and health students at the Faculty of Sports Science, State University of Malang. This research and development method includes: needs analysis, expert evaluation, small and large group product trials. Data analysis in this study used qualitative and descriptive quantitative percentage. The results of the evaluation by subject matter experts 79.6% good category, the results of small group trials 94.6% very good category, the results of large group trials 95.1% very good results. The conclusion obtained is that the sports physiology textbook product is suitable and can be used in courses in the department of physical education and health.
Lifeskill-Based Curriculum Development at Didaktika Uswatun Khasanah Kindergarten
Authors: Rohyati Rohyati , Fauzi Fauzi
Published: August 2023

Life skills education must be taught from an early age, not only as a provision for children to live their daily lives but also to face future life challenges. This study aims to determine the process of implementing a life skills-based curriculum and to find out how the development of aspects in children with the application of a life skills-based curriculum at Didaktika Uswatun Khasanah Kindergarten. The research was conducted from January 1 to February 1, 2023, at Didaktika Uswatun Khasanah Kindergarten, Beji Village, Kedungbanteng District, Banyumas Regency. The research method used is descriptive qualitative, with data collection techniques using observation, interviews, and documentation techniques. The life skill-based curriculum implemented at Didaktika Uswatun Khasanah Kindergarten aims to prepare students who have an attitude of independence and hone plural intelligence and responsibility by the stage of child development so that children can master basic skills at the age stage of the child. The success of this life skills-based curriculum results from cooperation between students, teachers, and school community members and mutual support in implementing learning programs.
Implementation of Feature Enginering and K-Mean Clustering Model in Predictive Analysis of Improving The Quality of Junior High School Education in Bogor Regency
Authors: Isbandi Isbandi , J Kamila Shonia , Wiwin Tri
Published: August 2023

In order to improve the quality of education. The government of the Republic of Indonesia has established the National Education Standard (SNP) which is the minimum criterion set by the government in the education system. SNP is a standard that must be met by every school and all stakeholders in managing and delivering education. Through data analysis using feature enginering and K-meann methods  to predict  the quality of junior high school education in Bogor Regency shows  that the junior high school education standards in Bogor Regency are significantly influenced by the achievement value of 3 education quality standards, namely educator and education staff standards, facilities and infrastructure standards, and management standards. So that the education office of Bogor Regency needs to focus the direction of policies to improve the quality of junior high school education in indicators that affect these 3 standards. The results of the k-men clustering of school quality showed that junior high schools in Bogor Regency were divided into 2 major groups of education quality level, namely below the value of the 5.07 education quality level as many as 57.12% of junior high schools and the rest above the value of the 5.07 education quality level of 42.88% of junior high schools.  Further development of the model needs to be further developed to the level of sub-indicators so that school quality can be more specifically measured, and the data used as analysis material is expanded and enriched by other educational data from various sectors so that the model developed can be more comprehensive in measuring the achievement of education quality.
Education Financing Management in Integrated Islamic Schools
Authors: Ningsih Sinta , Rohaniah Ai
Published: August 2023

This study aims to determine how the management of education financing of Integrated Islamic Schools. The research method used is a literature review. Based on the results of data analysis, it is known that the funding of Integrated Islamic School education refers to the National Education Standard (SNP) contained in Government Regulation No. 19 of 2005 Chapter IX Article 62 concerning Financing Standards and related Ministerial Regulations (Regulation No. 69 of 2009). The Foundation as the manager of an integrated Islamic educational institution, carries out management as determined by the Integrated Islamic School Network as stated in the Integrated Islamic School Quality Standards. The Foundation has limitations in financing learning and extracurricular activities and procuring infrastructure facilities. There are several types of activities in which schools are given the authority to manage finances or sources of income.
Quran Memorization Method: A Comparative Study between Listening Method and Reading Method
Authors: Sari Wulan
Published: August 2023

The Qur'an must be memorized throughout time, beginning at the appropriate moment and ending after placing each verse. Writing down poetry, listening to them, and reading them aloud are all steps in the memorizing process. The process of memorizing will provide excellent outcomes if it is completed accurately and on schedule. Understanding the advantages of memorization and its aim can help you maintain the Qur'an in your memory. There will be a barrier to students remembering the Quran after memorization. This kind of study is qualitative research, a method that gathers data in the form of variables but sees them as a component of a whole. An analysis of the relevant literature was employed as the method for gathering data in this study. In this research, qualitative analysis was the method of data analysis. The survey's findings revealed that the memorization process used in schools was quite effective, including: 1) the school's process of seeking out teachers with teaching experience; 2) the use of memorization aids like the Qur'an, the blackboard, a memorization-friendly environment, and an adequate sound system.
The Influence of Online Games on The Social Behavior of High School Students
Authors: Muminah Aisyah Farah , Haryanto Budi , Astutik Anita Puji
Published: August 2023

Several aspects of life are currently undergoing transformations due to the rapid advancement of communication technology, and one such aspect is entertainment, specifically online games. The primary purpose of online games is to provide amusement to individuals and prevent them from experiencing boredom after completing routine tasks. However, individuals become addicted to online games primarily due to the intense gameplay, particularly among teenage groups. Even excessive online games has negative consequences, including social inequality such as timelessness and a decline in manners. This study aimed to examine the correlation between online games and the social behavior of high school students in the Bangil District. This study employed a quantitative method utilizing an analytical survey. The sampling technique employed was purposive sampling, conducted in several coffee shops within the Bangil District, with a sample size of 50 respondents. The findings of this study revealed a negative impact of online games on the social behavior of high school students, as indicated by the equation Y = 5.066 + 0.848X, demonstrating a significant influence. The correlation between X and Y is 0.774, indicating a negative relationship between the variables. The remaining 0.226 falls outside the scope of this investigation. There existed a strong and significant negative relationship between online games and the social behavior of high school students. The impact of online games on students' social behavior manifested in several negative aspects, including the usage of harsh language, disruption of daily productivity leading to health deterioration, failure to keep promises to others, neglecting religious worship, abandoning tasks, and a decrease in the display of empathy towards others.

Keywords: Online Games, Social Behavior, Student
Ink Trails
Authors:   , Swain Arpit Chandan
Published: August 2023

Every encountered pathogen leaves an imprint on the immune system. This is termed as immune memory. A significant part of this immune memory is stored in a subset of T cells called memory T cells. As memory T cells are experienced in pathogen control, they are of significant interest to immunologists in their search for better vaccine technologies. For example, if the condition and the time of when memory T cells are formed is known, then technologies can be developed that either increase the number of memory T cells produced to better fend off an infection or decrease the number of memory T cells created to limit self-harm in autoimmune diseases. Similarly, if the lifespan of both an individual memory T cell and the memory T-cell population is known, questions on the efficacy and longevity of vaccines can be addressed. Therefore, it is essential to detail the mechanisms underlying the generation and maintenance of memory T cells. This thesis presents experimental data, their mathematical analyses and theoretical simulations that 1) discuss the lifespan of memory T cells, 2) ways to accurately approximate these lifespans, 3) the events leading up to the generation of memory T cells during an immune response and 4) probable mechanisms that could sustain the immunity provided by memory T cells against a pathogen for longer.
Európska prokuratúra v Slovenskej republike
Authors:   Pavol Jozef Šafárik University in Košice, Jánošíková Martina , Marčoková Becková Dominika
Published: August 2023

Recenzovaný zborník vedeckých prác je venovaný problematike Európskej prokuratúry a je výsledkom riešenia projektu podporeného Agentúrou na podporu výskumu a vývoja č. APVV-18-0421 Európska prokuratúra v súradniciach ústavného poriadku Slovenskej republiky ako posilnenie európskej integrácie prostredníctvom práva. Autori vedeckých prác sa vo svojich prácach venujú problematike Európskej prokuratúry v kontexte práva Európskej únie a trestného práva, ako aj vzťahu Európskej prokuratúry s vnútroštátnou prokuratúrou a orgánmi činnými v trestnom konaní. Vedecké práce uverejnené v zborníku sa zaoberajú témami dôvodov vzniku Európskej prokuratúry, postavenia Európskej prokuratúry v inštitucionálnom systéme EÚ a SR, vzťahov kooperácie a koordinácie medzi Európskou prokuratúrou a prokuratúrou Slovenskej republiky, ochrany ústavnosti a zákonnosti postupov a rozhodnutí Európskej prokuratúry s osobitným zreteľom na ochranu základných práv, ako i prvým výsledkom a hodnoteniam pôsobenia Európskej prokuratúry v SR. Vďaka obsahovému spracovaniu príspevkov môže čitateľ získať ucelenejšiu predstavu o tomto novom orgáne Európskej únie, ktorý pôsobí v oblasti tradične spájanou so suverenitou štátu a predstavuje tak ďalší posun v integračných procesoch reprezentovaných Európskou úniou. URL: https://unibook.upjs.sk/
Občianstvo v kontexte etiky starostlivosti
Authors:   Univerzita Pavla Jozefa Šafárika v Košiciach, Jesenková Adriana
Published: August 2023

Učebnica Občianstvo v kontexte etiky starostlivosti sa snaží predstaviť študentkám a študentom humanitných a spoločenskovedných odborov aktuálne otázky občianstva z perspektívy špecifickej morálno-filozofickej teórie, a to feministickej morálnej filozofie, konkrétne feministickej etiky starostlivosti. Tradične je totiž téma občianstva a otázky s ňou späté vnímaná a skúmaná ako téma politického myslenia a politickej teórie. O občianstve uvažujeme dominantne ako o politickej kategórii, ktorá má byť predmetom skúmania najmä politických vied, prípadne spoločenskovedných disciplín. Minulosť aj aktuálna súčasnosť nás vyzývajú premýšľať o občianstve v súvislosti s ľudskosťou a spolupatričnosťou, a teda z morálnej perspektívy. Chápať občianstvo len ako politickú kategóriu a politickú inštitúciu je nedostatočné. Konceptuálne oddelenie politiky od morálky a etiky má za dôsledok, že máme ťažkosti s pochopením občianstva ako morálne relevantnej kategórie a ako etickej hodnoty. To nám následne bráni dôsledne kriticky analyzovať predpoklady, ktoré stoja v základoch nášho chápania občianstva, a napokon, aj identifikovať príčiny a faktory, ktoré prispievajú k zlyhávaniu občianskej spoločnosti, nedostatkom a deficitom v uplatňovaní občianstva ako vízie postavenej na slobode, rovnosti a solidarite. Aby sme teda dokázali brať morálku a jej argumenty vážne, potrebujeme o oboch premýšľať kontextuálne ako o vzájomne prepojených oblastiach života. Uvedená učebnica sa snaží priniesť alternatívny pohľad na občianstvo, ktorý sa opiera o feministickú kritiku kľúčových kategórií a pojmov spojených s občianstvom, ako sú sloboda, autonómia, rovnosť, univerzálne práva, demokracia, spravodlivosť alebo solidarita. Súčasná feministická etika starostlivosti predstavuje jeden z inšpiratívnych spôsobov, ako otázky politiky, moci a morálky chápať ako vzájomne sa podmieňujúce a prepletené. Učebnica tak objasňuje hodnoty späté s demokratickým občianstvom, a zároveň potenciál feministickej etiky starostlivosti ako analytického, evaluačno-kritického a aplikačného nástroja pre porozumenie a skúmanie pojmu občianstva a praxe občianstva ako starostlivej praxe a praxe starostlivosti o dobrý život v občianskej spoločnosti.
Effect of Laparoscopic Sleeve Gastrectomy on Serum Adipokine Levels
Authors: Cibičková Ľ , Grega M , Dohnal R , Schovánek J
Published: August 2023

Bariatric procedures are considered to be the most effective treatment options for obesity. One of them is laparoscopic sleeve gastrectomy (LSG), which is nowadays very popular and widely used. LSG leads to weight loss and metabolic improvement and also changes adipokine levels, although it is just a restrictive operation. We describe changes in pro-inflammatory (leptin, resistin, visfatin and chemerin) and anti-inflammatory adipokines (adiponectin, omentin), with adiponectin and leptin being most studied. Their levels are markedly changed after LSG and this may partially explain the weight loss seen after LSG. Adipokines are closely connected to insulin resistance and chronic inflammation both being positively influenced after LSG. Leptin regulates amount of body fat, appetite, thermogenesis and metabolic rate and its levels are positively correlated with both weight and BMI changes after operation. Resistin influences insulin sensitivity, modulates body cholesterol trafficking and its changes after operation correlate with BMI, waist circumference, fat mass, LDL cholesterol and C-reactive protein. Chemerin, an important component of immune system, decreases after bariatric surgery and its levels correlate with BMI, triglyceride levels, and blood glucose. On the other hand, pro-inflammatory adipokine adiponectin, which influences fatty acid oxidation, browning of fat tissue and energy metabolism, is declining after LSG. This decline explains improvement of glucose status after bariatric surgery in patients with diabetes and is correlated with BMI loss, waist circumference and LDL cholesterol level. Effect of LSG goes beyond calory restriction and the changes of adipokines have a great impact on health status of the bariatric patients.
Mechanisms and Effects of Macrophage Polarization and Its Specifics in Pulmonary Environment
Authors: Žaloudíková M
Published: August 2023

Macrophages are a specific group of cells found in all body tissues. They have specific characteristics in each of the tissues that correspond to the functional needs of the specific environment. These cells are involved in a wide range of processes, both pro-inflammatory and anti-inflammatory (“wound healing”). This is due to their specific capacity for so-called polarization, a phenotypic change that is, moreover, partially reversible compared to other differentiated cells of the human body. This promises a wide range of possibilities for its influence and thus therapeutic use. In this article, we therefore review the mechanisms that cause polarization, the basic classification of polarized macrophages, their characteristic markers and the effects that accompany these phenotypic changes. Since the study of pulmonary (and among them mainly alveolar) macrophages is currently the focus of scientific interest of many researchers and these macrophages are found in very specific environments, given mainly by the extremely high partial pressure of oxygen compared to other locations, which specifically affects their behavior, we will focus our review on this group.
KOMUNIKASI ANTARPRIBADI PEMANDU MUSEUM PADA LAYANAN VIRTUAL TOUR MUSEUM KEHUTANAN MELALUI APLIKASI ZOOM
Authors: Wulandari Yulianti Fajar , Rahastine Mareta Puri , Bastian Yan , Murtiadi Murtiadi , Pranawukir Iswahyu
Published: August 2023

Museum Kehutanan merupakan destinasi wisata di Jakarta yang dikelola Kementerian Lingkungan Hidup dan Kehutanan. Pandemi yang melanda selama dua tahun membuat Museum Kehutanan mengadaptasi layanan publik dengan menggunakan teknologi komunikasi kekinian, yakni virtual tour dengan memanfaatkan aplikasi zoom. Interaksi sosial dan komunikasi antarpribadi yang terbangun dalam layanan virtual tour antara Pemandu Museum Kehutanan selaku Komunikator dan Para peserta Layanan Virtual Tour sebagai Komunikan menarik untuk diteliti. Tujuan penelitian ini adalah memahami dan menjelaskan peran komunikasi antarpribadi Pemandu Museum dalam layanan virtual tour Museum Kehutanan melalui aplikasi zoom. Penelitian ini menggunakan metode deskriptif kualitatif dengan desain studi kasus di Museum Kehutanan. Hasil penelitian menunjukan bahwa Pemandu Museum Kehutanan dalam proses interaksi sosial dan komunikasi antar pribadi melakukan pendekatan sesuai teori DeVito, yakni keterbukaan, empati, sikap mendukung, sikap positif dan kesetaraan, agar kegiatan virtual tour tidak membosankan dan berkesan bagi Peserta untuk datang berkunjung secara langsung di Museum Kehutanan. Respon peserta virtual tour sangat positif dan berharap dapat memotivasi siswa untuk aktif mencari pengetahuan agar berprestasi baik di sekolah.
PERTUMBUHAN EKONOMI, INDEKS PEMBANGUNAN MANUSIA DAN KEMISKINAN : BUKTI DARI PROVINSI BENGKULU
Authors: Tanjung Ega Permana , Yuhendri L.V
Published: August 2023

This study aims to investigate relationship economic growth and the human development index and poverty in Bengkulu Province between 2011 and 2021. Associative descriptive research techniques use secondary data from the Central Bureau of Statistics. The material breakdown employed Eviews 12 application is panel data regression analysis. The study's findings demonstrate how poverty in Bengkulu Province is both directly impacted. In the partial, poverty in Bengkulu Province is positively and insignificantly impacted by Economic Growth. Than, poverty in Bengkulu Province is negatively and significantly impacted by Human Development Index. In the simultaneously, poverty in Bengkulu Province is significantly impacted by both the economic growth and human development index.
Vérképzőrendszeri eltérések és koagulációs zavarok közösségben szerzett pneumoniához társuló szepszisben
Authors: Bozóky Géza , Ruby Éva , Mohos Andrea
Published: August 2023

A szepszissel szövődött, közösségben szerzett pneumoniában a sokszervi funkciózavar mellett gyakorta jelentkeznek különböző súlyosságú vérképzőrendszeri eltérések és a haemostasisrendszer zavarai. A 2012– 2020 közötti időszakban 1826 betegben kórisméztünk közösségben szerzett pneumoniát, közülük 218 esetben a jellegzetes klinikai tünetek és laboratóriumi eltérések alapján szepszis kialakulását észleltük. Ezen szeptikus betegeinkben vizsgáltuk az anaemia előfordulásának gyakoriságát, súlyosságát, a fehérvérsejtek mennyiségi és minőségi változásait, a thrombocyták számbeli eltéréseit, valamint az alvadási rendszerben bekövetkezett kóros irányú történéseket. Szeptikus betegeinkben a leg - gyakoribb jellegű vérképzőrendszeri eltérésnek az anaemia (n = 159) és a leukocytosis (n = 151) bizonyult. Extrém fokú leucocytosist (fehérvérsejtszám > 50000/µl) hat esetben kórisméztünk. A fehérvérsejtszám csökkenését (leukopenia, agranulocytosis) 34 betegben észleltük. Három esetben igazolódott leukemoid reakció: a leucocytosis mellett a perifériás vérképben ki fejezett balra tolt fehérvérsejtrendszeri el térések, valamint myelocyták, metamyelocyták voltak láthatók, néhány atípusos myeloid sejt jelenléte mellett. Egy betegben a Jamshidi-módszerrel végeztünk cristabiopsziát, mivel a perifériás vérképben súlyos fokú pancytopenia igazolódott. A cristabiopszia szövettani feldolgozása, értékelése myelodysplasiás jellegű csontvelő eltéréseket igazolt. Szeptikus betegeinkben vizsgálva a thrombocyták mennyiségi változásait, a thrombocytopenia elő fordulása dominált (n = 82).
Enfermedad cerebrovascular: mortalidad intra y extra hospitalaria
Authors:   Hospital Basico IESS Guaranda, Bracho Irausquín René Alexander ,   Universidad Nacional Experimental Francisco de Miranda, Bracho Irausquín Robert Manuel ,   Servicio Autónomo Docente Hospital Central de Maracay,   Universidad de Carabobo, Rodríguez Bracho Sorelys Josefina ,   Servicio Autónomo Docente Hospital Central de Maracay,   Universidad de Carabobo
Published: August 2023

La enfermedad cerebrovascular comprende un trastorno frecuente y devastador, ocupando la segunda causa de muerte a nivel mundial. La hipertensión arterial sistémica conlleva un riesgo significativo de ictus, implicado tanto en el isquémico como en el ictus hemorrágico. Son desconocidos los datos acerca de los factores de mortalidad de enfermedad cerebrovascular en la localidad. El objetivo del presente estudio fue evaluar la mortalidad por Enfermedad Cerebrovascular y sus factores asociados en los pacientes que ingresan al Servicio de Medicina Interna del Hospital Central de Maracay estado Aragua, Venezuela en el período Noviembre 2021 – Agosto 2022.Se realizó un estudio no experimental, clínico, descriptivo, prospectivo y longitudinal; incluyó 345 pacientes con ictus agudo según criterios de inclusión; a quienes se realizó seguimiento intrahospitalario y extrahospitalario al egreso. En los resultados predominó el sexo masculino 53,91%, la edad promedio fue de 66,46 ±12,68 años, con etiología más frecuente isquémico 61,74%, seguido de hematoma intraparenquimatoso 27,25%; NIHSS al ingreso con media de 13,68 ±5,61; Glasgow 12,56 ±1,7; condición al egreso 17,39% fallecieron durante la hospitalización, 11,39% fallecieron a nivel extrahospitalario. La comorbilidad predominante fue la hipertensión arterial sistémica con 82,61%; la muerte fue más frecuente en pacientes con emergencia hipertensiva y necesidad de soporte ventilatorio (OR>1). Se percibió que la presencia de hipertensión arterial sistémica, no cumplimiento del tratamiento, emergencia hipertensiva conlleva un alto riesgo de mortalidad; al igual que la adquisición de infecciones nosocomiales como neumonía y ameritar soporte ventilatorio, por lo cual el manejo de los factores de riesgo son claves para la evolución del ictus agudo.
Recent developments in nanomaterials for upgrading treatment of orthopedics diseases
Authors: Shang Jinxiang , Zhou Chao , Jiang Chanyi , Huang Xiaogang , Liu Zunyong , Zhang Hengjian , Zhao Jiayi , Liang Wenqing , Zeng Bin
Published: August 2023

Nanotechnology has changed science in the last three decades. Recent applications of nanotechnology in the disciplines of medicine and biology have enhanced medical diagnostics, manufacturing, and drug delivery. The latest studies have demonstrated this modern technology’s potential for developing novel methods of disease detection and treatment, particularly in orthopedics. According to recent developments in bone tissue engineering, implantable substances, diagnostics and treatment, and surface adhesives, nanomedicine has revolutionized orthopedics. Numerous nanomaterials with distinctive chemical, physical, and biological properties have been engineered to generate innovative medication delivery methods for the local, sustained, and targeted delivery of drugs with enhanced therapeutic efficacy and minimal or no toxicity, indicating a very promising strategy for effectively controlling illnesses. Extensive study has been carried out on the applications of nanotechnology, particularly in orthopedics. Nanotechnology can revolutionize orthopedics cure, diagnosis, and research. Drug delivery precision employing nanotechnology using gold and liposome nanoparticles has shown especially encouraging results. Moreover, the delivery of drugs and biologics for osteosarcoma is actively investigated. Different kind of biosensors and nanoparticles has been used in the diagnosis of bone disorders, for example, renal osteodystrophy, Paget’s disease, and osteoporosis. The major hurdles to the commercialization of nanotechnology-based composite are eventually examined, thus helping in eliminating the limits in connection to some pre-existing biomaterials for orthopedics, important variables like implant life, quality, cure cost, and pain and relief from pain. The potential for nanotechnology in orthopedics is tremendous, and most of it looks to remain unexplored, but not without challenges. This review aims to highlight the up tp date developments in nanotechnology for boosting the treatment modalities for orthopedic ailments. Moreover, we also highlighted unmet requirements and present barriers to the practical adoption of biomimetic nanotechnology-based orthopedic treatments.
Investigation of bacterial neuraminidase inhibition of xanthones bearing geranyl and prenyl groups from Cratoxylum cochinchinense
Authors: Kim Jeong Yoon , Li Zuo Peng , Lee Gihwan , Kim Jeong Ho , Shah Abdul Bari , Lee Yong Hyun , Park Ki Hun
Published: August 2023

Introduction: The root of Cratoxylum cochinchinense has been widely used as Chinese folk medicine to cure fevers, burns, and abdominal complications because it contains various bioactive metabolites such as xanthones, triterpenes, and flavonoids. In this study, we estimated bacterial neuraminidase inhibition with a series of xanthones from C. cochinchinense. BNA has connected to various biological functions such as pathogenic bacteria infection inflammatory process after infection and biofilm formation.

Methods: The identification of xanthones (1–6) bearing geranyl and prenyl groups was established by spectroscopic data using UV, IR, NMR, and HREIMS. BNA inhibitory modes of isolated xanthones were investigated by Double-reciprocal plots. Moreover, the competitive inhibitor was evaluated the additional kinetic modes determined by kinetic parameters (k3, k4, and Kiapp). The molecular docking (MD) and molecular dynamics simulations (MDS) studies also provided the critical information regarding the role of the geranyl and prenyl groups against BNA inhibition.

Results: A series of xanthones (1–6) appended prenyl and geranyl groups on the A-ring were isolated, and compounds 1–3 were shown to be new xanthones. The analogues within this series were highly inhibited with excellent affinity against bacterial neuraminidase (BNA). A subtle change in the prenyl or geranyl motif affected the inhibitory potency and behavior significantly. For example, the inhibitory potency and binding affinity resulting from the geranyl group on C4: xanthone 1 (IC50 = 0.38 μM, KA = 2.4434 × 105 L·mol−1) were 100-fold different from those of xanthone 3 (IC50 = 35.8 μM, KA = 0.0002 × 105 L·mol−1). The most potent compound 1 was identified as a competitive inhibitor which interacted with BNA under reversible slow-binding inhibition: Kiapp = 0.1440 μM, k3 = 0.1410 μM−1s−1, and k4 = 0.0203 min−1. The inhibitory potencies (IC50) were doubly confirmed by the binding affinities (KA).

Discussion: This study suggests the potential of xanthones derived from C. cochinchinense as promising candidates for developing novel BNA inhibitors. Further research and exploration of these xanthones may contribute to the development of effective treatments for bacterial infections and inflammatory processes associated with BNA activity.
The crosstalk between microbiota and metabolites in AP mice: an analysis based on metagenomics and untargeted metabolomics
Authors: Zhou Qi , Tao Xufeng , Guo Fangyue , Zhu Yutong , Wu Yu , Xiang Hong , Shang Dong
Published: August 2023

Background and purpose

Microbiome dysfunction is known to aggravate acute pancreatitis (AP); however, the relationship between this dysfunction and metabolite alterations is not fully understood. This study explored the crosstalk between the microbiome and metabolites in AP mice.

Methods

Experimental AP models were established by injecting C57/BL mice with seven doses of cerulein and one dose of lipopolysaccharide (LPS). Metagenomics and untargeted metabolomics were used to identify systemic disturbances in the microbiome and metabolites, respectively, during the progression of AP.

Results

The gut microbiome of AP mice primarily included Firmicutes, Bacteroidetes, Actinobacteria, and Proteobacteria, and “core microbiota” characterized by an increase in Proteobacteria and a decrease in Actinobacteria. The Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis found that significantly different microbes were involved in several signaling networks. Untargeted metabolomics identified 872 metabolites, of which lipids and lipid-like molecules were the most impacted. An integrated analysis of metagenomics and metabolomics indicated that acetate kinase (ackA) gene expression was associated with various gut microbiota, including Alistipes, Butyricimonas, and Lactobacillus, and was strongly correlated with the metabolite daphnoretin. The functional gene, O-acetyl-L-serine sulfhydrylase (cysK), was associated with Alistipes, Jeotgalicoccus, and Lactobacillus, and linked to bufalin and phlorobenzophenone metabolite production.

Conclusion

This study identified the relationship between the gut microbiome and metabolite levels during AP, especially the Lactobacillus-, Alistipes-, and Butyricimonas-associated functional genes, ackA and cysK. Expression of these genes was significantly correlated to the production of the anti-inflammatory and antitumor metabolites daphnoretin and bufalin.
Comparison of fetal heart rate baseline estimation by the cardiotocograph network and clinicians: a multidatabase retrospective assessment study
Authors: Bai Jieyun , Pan Xiuyu , Lu Yaosheng , Zhong Mei , Wang Huijin , Zheng Zheng , Guo Xiaohui
Published: August 2023

Background

This study aims to compare the fetal heart rate (FHR) baseline predicted by the cardiotocograph network (CTGNet) with that estimated by clinicians.

Material and methods

A total of 1,267 FHR recordings acquired with different electrical fetal monitors (EFM) were collected from five datasets: 84 FHR recordings acquired with F15 EFM (Edan, Shenzhen, China) from the Guangzhou Women and Children's Medical Center, 331 FHR recordings acquired with SRF618B5 EFM (Sanrui, Guangzhou, China), 234 FHR recordings acquired with F3 EFM (Lian-Med, Guangzhou, China) from the NanFang Hospital of Southen Medical University, 552 cardiotocographys (CTG) recorded using STAN S21 and S31 (Neoventa Medical, Mölndal, Sweden) and Avalon FM40 and FM50 (Philips Healthcare, Amsterdam, The Netherlands) from the University Hospital in Brno, Czech Republic, and 66 FHR recordings acquired using Avalon FM50 fetal monitor (Philips Healthcare, Amsterdam, The Netherlands) at St Vincent de Paul Hospital (Lille, France). Each FHR baseline was estimated by clinicians and CTGNet, respectively. And agreement between CTGNet and clinicians was evaluated using the kappa statistics, intra-class correlation coefficient, and the limits of agreement.

Results

The number of differences <3 beats per minute (bpm), 3-5 bpm, 5–10 bpm and ≥10 bpm, is 64.88%, 15.94%, 14.44% and 4.74%, respectively. Kappa statistics and intra-class correlation coefficient are 0.873 and 0.969, respectively. Limits of agreement are −6.81 and 7.48 (mean difference: 0.36 and standard deviation: 3.64).

Conclusion

An excellent agreement was found between CTGNet and clinicians in the baseline estimation from FHR recordings with different signal loss rates.
Vs30 and depth to bedrock estimates from integrating HVSR measurements and geology-slope approach in the Oslo area, Norway
Authors: Ghione Federica , Köhler Andreas , Dichiarante Anna Maria , Aarnes Ingrid , Oye Volker
Published: August 2023

In order to estimate well-constrained seismic hazard and risk on local scales, the knowledge of site amplification factors is one of several important requirements. Seismic hazard studies on national or regional scales generally provide the level of earthquake shaking only at bedrock conditions, thereby avoiding the difficulties that are caused through local site effects. Oftentimes, local site conditions are not well understood or even non-existent. In this study we investigate an efficient and non-invasive methodology to derive the local average shear wave velocity in the uppermost 30 m of the ground (Vs30). The Vs30 value is a useful parameter to define soil classes and soil amplification used in seismic hazard assessment and to extend the knowledge of the site to include the depth to basement rock. At the level of the municipality of Oslo, there is currently no map available that describes the Vs30, and as such any seismic risk study is lacking potentially critical information on local site amplification. The new proposed methodology includes the use of existing well databases (with knowledge on minimum basement depth), topographic slope derived from Digital Elevation Models (as a proxy for both depth to basement and Vs30, integrated with geological maps) and near-surface Quaternary geological maps. The Horizontal to Vertical Spectral Ratio (HVSR) method and a statistics-based geological mapping tool (COHIBA) are used to integrate the various sources of data estimates. Finally, we demonstrate our new methodology and workflow with data from three different regions within the Oslo municipality and propose an approach to conduct cost-efficient mapping for seismic site amplification on a general municipality scale.
Research trends around open innovation in higher education: advancements and future direction
Authors: Valencia-Arias Alejandro , Gómez-Bayona Ledy , Moreno-López Gustavo , Sialer-Rivera Noelia , Bernal Olga-Vélez , Gallegos Ada , Arias-Vargas Francisco Javier
Published: August 2023

Open innovation in higher education has emerged as a vital approach, especially in the context of the COVID-19 pandemic, to foster collaboration, knowledge exchange, and address challenges in the academic sector. This study investigates the impact of open innovation on entrepreneurial skills, value co-creation, and technology transfer barriers by examining collaborations between universities and industries in emerging economies and knowledge absorption in SMEs. Additionally, it underscores the significance of open innovation in enhancing teaching and learning quality and aligning with Sustainable Development Goals. To address research gaps, a bibliometric study using VOSviewer software is proposed, aiming to analyze co-occurrence between keywords and explore the relationships between variables. Following the PRISMA statement’s parameters for systematic literature review, the methodology ensures a comprehensive and replicable approach for accurate findings. The study reveals an increasing trend in literary production, with the United Kingdom and Spain leading academic progress. Prominent research trends include technology transfer through open innovation strategies, diversification of business models due to innovation policies, factors influencing collaboration between companies and universities, and the emergence of Education 4.0 with novel educational systems leveraging technology. These findings have implications for supporting the education sector, benefiting students, graduates, and the broader community.