bluuebunny/crossref_metadata_2025 huggingface dataset:
RamaNet: Computational de novo helical protein backbone design using a long short-term memory generative neural network
Authors: Sabban Sari , Markovsky Mikhail
Published: September 2020

The ability to perform de novo protein design will allow researchers to expand the variety of available proteins. By designing synthetic structures computationally, they can utilise more structures than those available in the Protein Data Bank, design structures that are not found in nature, or direct the design of proteins to acquire a specific desired structure. While some researchers attempt to design proteins from first physical and thermodynamic principals, we decided to attempt to test whether it is possible to perform de novo helical protein design of just the backbone statistically using machine learning by building a model that uses a long short-term memory (LSTM) architecture. The LSTM model used only the φ and ψ angles of each residue from an augmented dataset of only helical protein structures. Though the network’s generated backbone structures were not perfect, they were idealised and evaluated post generation where the non-ideal structures were filtered out and the adequate structures kept. The results were successful in developing a logical, rigid, compact, helical protein backbone topology. This paper is a proof of concept that shows it is possible to generate a novel helical backbone topology using an LSTM neural network architecture using only the φ and ψ angles as features. The next step is to attempt to use these backbone topologies and sequence design them to form complete protein structures.
Assessing the impact of tobacco control policies on smokeless tobacco uptake and use among secondary school students in South Asia: protocol for a feasibility study of conducting longitudinal surveys
Authors: Mishu Masuma Pervin , Siddiqi Kamran , McNeill Ann , Kanaan Mona , Jackson Cath , Huque Rumana , Kanan Sushama , Abdullah S.M. , Fieroze Fariza , Garg Suneela , Singh M. Meghachandra , Borle Amod L. , Deshmukh Chetana , Akhter Zohaib , Mazhar Laraib , Khan Zohaib , Rehman Khalid , Ullah Safat , Han Lu , Readshaw Anne , Iqbal Romaina
Published: September 2020

Background: Smokeless tobacco (ST) use is common among youth in South Asia where 85% of the world’s 300 million ST users live and use the most lethal ST forms. Little is known about the impact of tobacco control policies on the youth ST uptake in those countries. We planned to conduct longitudinal surveys among secondary school students to evaluate existing tobacco control policies on ST uptake and use, and a feasibility study for that prospective, observational cohort study.

Study objectives: (1) To demonstrate the feasibility of selection, recruitment and retention of schools and of study participants; (2) To assess the feasibility and acceptability of the study procedure and study tool (questionnaire); (3) To assess if the questionnaire can assess tobacco uptake and use, and the potential predictors of tobacco uptake and use of the envisaged main study.

Methods and analysis: The feasibility study will be conducted in two administrative areas within each of three South Asian countries: Bangladesh, India and Pakistan. We will use both quantitative and qualitative data collection methods. Eight eligible secondary schools will be randomly selected within purposively selected sub-districts from each country. We plan to conduct one baseline and one follow up survey among secondary school students, one year apart. At each time point, data on tobacco uptake and the potential predictors will be collected from students via self-administered questionnaires. The qualitative component will be embedded into the study with each round of data collection to assess the acceptability of the study instrument (questionnaire) and data collection methods, via focus group discussions with students and semi-structured interviews with schoolteachers.

Recruitment and retention rates, completeness of the questionnaires, frequencies and associations of tobacco use and explanatory variables will be reported. Data gathered from the focus group and interviews will be analysed using the framework approach.
Extraction of CPRD additional clinical data using R
Authors: Nash Anthony , Cader M. Zameel
Published: September 2020

The Clinical Practice Research Datalink is a nation-wide database of primary healthcare data records in England (UK) linked to several health services. A visit to a health practitioner can result in the digital storing of diagnostic and prescription therapeutic information. Access to patient primary care and linked service data depends on the research in mind; however, typically several flat files that describe patient interactions with a health practitioner are delivered. Some of these files will describe additional data such as the result of medical tests and patient lifestyles, denoted collectively into entity values. This data is used to supplement the medical notes recorded by a general practitioner. We have made available a set of R scripts that reads the clinical flat files, additional clinical flat files and entity values, and returns patient clinical data linked with the requested additional data. We have also included medcode descriptions associated with several entities along with instruction of how to extend the code for additional entities. The code is free to download under the MIT license: https://github.com/acnash/CPRD_Additional_Clinical
On the use of real-time reported mortality data in modelling and analysis during an epidemic outbreak
Authors: Liljenberg Per
Published: September 2020

Background: For diseases like Covid-19, where it has been difficult to identify the true number of infected people, or where the number of known cases is heavily influenced by the number of tests performed, hospitalizations and deaths play a significant role in understanding the epidemic and in determining the appropriate response. However, the Covid-19 deaths data reported by some countries display a significant weekly variability, which can make the interpretation and use of the death data in analysis and modeling difficult.

Methods: We derive the mathematical relationship between the series of new daily deaths by reporting date and the series of deaths by death date. We then apply this formalism to the corresponding time-series reported by Sweden during the Covid-19 pandemic.

Results: The practice of reporting new deaths daily, as is standard procedure during an outbreak in most countries and regions, should be viewed as a time-dependent filter, modulating the underlying true death curve. After having characterized the Swedish reporting process, we show how smoothing of the Swedish reported daily deaths series results in a curve distinctly different from the true death curve. We also comment on the use of nowcasting methods.

Conclusions: Modelers and analysts using the series of new daily deaths by reporting date should take extra care when it is highly variable and when there is a significant reporting delay. It might be appropriate to instead use the series of deaths by death date combined with a nowcasting algorithm as basis for their analysis.
Housing with support for older people: a mixed-methods systematic review protocol
Authors: Coyle Camille , Buggy Sarah , Cagney Olivia , Farragher Louise , Lee Caitriona , Patje Darren , Long Jean
Published: September 2020

Background: The implementation of housing with support is rapidly expanding, particularly as life expectancy is increasing throughout the world. This expansion is likely to intensify in the context of coronavirus disease 2019 (COVID-19), which has revealed the risks of relying primarily on nursing homes. This mixed-methods systematic review aims to: 1) explore older people’s perceptions and experiences of housing with support and 2) examine the impact of providing housing with support for older people.

Methods: The databases Ovid Medline, Ovid Social Policy & Practice, EBSCO CINAHL, and EBSCO SOCIndex will be searched, and grey literature will also be identified. Quality assessment will be carried out using Joanna Briggs Institute’s Critical Appraisal Checklist for Qualitative Research as well as a tool from the National Institutes of Health for observational cohort studies. This review will employ convergent parallel design; as such, qualitative and quantitative findings will be synthesised separately in the initial stage of analysis. The results from the qualitative and quantitative syntheses will then be integrated in the final stage of the analysis.

Conclusion: This systematic review will synthesise the evidence regarding older people’s perceptions and experiences of housing with support and the impact of providing housing with support for older people on their quality of life.
Implementing a National Approach to Research Ethics Review during a Pandemic – the Irish Experience
Authors: Sheehy Aileen , Ralph James Jennifer , Horgan Mary
Published: September 2020

The surge of coronavirus disease 2019 (COVID-19) research studies involving human participants in response to the pandemic has meant that research ethics committees across the world have been challenged to adapt their processes to meet demand while retaining high standards of review. Ethics review during this pandemic remains essential to ensure the safety, dignity and well-being of research participants, however research ethics committees are now faced with new, and often complex, ethics considerations and logistical challenges.

This Open Letter looks specifically at the Irish experience of establishing a national approach to research ethics review amidst a global pandemic. This represents Ireland’s first National Research Ethics Committee, which provided the research community with an expedited and ‘single national opinion’ for ethics review for COVID-related research. The insights gleaned and lessons learned from the Irish experience may inform emergency responses to future pandemics or public health emergencies.
On the Role of Anaphora and Cataphora in Deixis Research
Authors: Alekseeva M. , Klyueva E.
Published: September 2020

This paper focuses on different types of deixis, particularly on anaphora and cataphora. Anaphora indicates what has been said previously, cataphora precedes what is going to be said. They are very important for the cohesion in the text in oral and written communication. These two constituents use the same means of expression.
CPD article: Arthropathy of the temporomandibular joint: a diagnostic challenge
Authors: Hellige Maren
Published: September 2020

Equine temporomandibular joint arthropathy has been described as an underlying cause of various clinical signs. The anatomy of this incongruent joint is well described, as well as its appearance on different imaging modalities. However, pathologies of this joint are rare. This article provides an overview of the literature. Multiple possible aetiologies of temporomandibular joint arthropathy are not supported by current research and must be revised. Likewise, the imaging diagnosis or the classification of clinically relevant findings is difficult. A critical examination of this disease, including multiple diagnostic modalities, should be carried out to verify the clinical significance of findings in every case.
A Simple Method for P-waves Velocity Estimation Using Pore Attributes Shape Factor and Tortuosity
Authors: Burhannudinnur Muhammad , Prakoso Suryo
Published: September 2020

Several researchers have arranged an approach to estimating the P-wave velocity, but none of them specifically relates to the pore attribute. Pore attributes are one of the main factors that affect pore complexity and rock quality. If P-wave velocity is influenced by the pore complexity, then it should be possible to arrange a simple relationship of P-wave velocity with the pore attribute. This study is intended to construct an empirical relationship of P-wave velocity with a combination of pore attributes, shape factor, and tortuosity (Fsτ) so that the P-wave velocity can be easily estimated. This study used two sandstone datasets from 2 different basins, which are the northern part of the West Java basin and the Kutai basin. This research shows that a simple empirical equation can be arranged to relate the P-wave velocity with Fsτ. This relationship provides a good correlation coefficient. It offers an easy and straightforward approach to estimating P-wave
The subjective meaning of gender: how survey designs affect perceptions of femininity and masculinity
Authors: Markstedt Elias , Wängnerud Lena , Solevid Maria , Djerf-Pierre Monika
Published: September 2020

The rationale for this study is that self-categorising rating scales are becoming increasingly popular in large-scale survey research moving beyond binary ways of measuring gender. We are referring here to the use of rating scales that are similar to graded scales capturing left–right or liberal–conservative political ideology, that is, scales that do not include predefinitions of the core concepts (femininity/masculinity, as compared to left/right or liberal/conservative). Yet, previous studies including such non-binary gender measures have paid little attention to potential effects of survey designs. Using an experimental set-up, we are able to show that sequencing of gender measurements influences the answers received. Men were especially affected by our treatments and rated themselves as significantly ‘less masculine’ when prompted to reason about the meaning of gender prior to self-categorisation on scales measuring degrees of femininity and masculinity. Moreover, self-categorising seems to trigger more biological understandings of gender than anticipated in theory.
3D reconstruction of objects with occlusion and surface reflection using a dual monocular structured light system
Authors: He Kejing , Sui Congying , Lyu Congyi , Wang Zerui , Liu Yunhui
Published: September 2020

Three-dimensional (3D) vision plays an important role in industrial vision, where occlusion and reflection have made it challenging to reconstruct the entire application scene. In this paper, we present a novel 3D reconstruction framework to solve the occlusion and reflection reconstruction issues in complex scenes. A dual monocular structured light system is adopted to obtain the point cloud from different viewing angles to fill the missing points in the complex scenes. To enhance the efficiency of point cloud fusion, we create a decision map that is able to avoid the reconstruction of repeating regions of the left and right system. Additionally, a compensation method based on the decision map is proposed for reducing the reconstruction error of the dual monocular system in the fusion area. Gray-code and phase-shifting patterns are utilized to encode the complex scenes, while the phase-jumping problem at the phase boundary is avoided by designing a unique compensation function. Various experiments including accuracy evaluation, comparison with the traditional fusion algorithm, and the reconstruction of real complex scenes are conducted to validate the method’s accuracy and the robustness to the shiny surface and occlusion reconstruction problem.
Advantages of AlGaN-based deep ultraviolet light-emitting diodes with graded quantum structures in the active region
Authors: Yu Huabin , Ren Zhongjie , Liu Zhongling , Xing Chong , Sun Haiding
Published: September 2020

AlGaN-based deep ultraviolet light-emitting diode (DUV LED) performance is far from satisfaction for commercialization owing to its poor external quantum efficiency, low hole injection efficiency, and large current leakage, etc. In our works, we investigated several DUV LEDs with special multi-quantum wells (MQWs) structures, including graded quantum wells (QWs) for mitigating the quantum confined Stark effect and graded quantum barriers (QBs) for enhancing the electron blocking capability as well as hole injection efficiency. We found that these unique MQW structures could remarkably improve the internal quantum efficiency, external quantum efficiency and light output power. The proposed structure with such promising graded QWs or graded QBs provides us an effective solution to boost optical power in the pursuit of high-performance DUV emitters.
Single/Multi-wavelength green laser diode system
Authors: Shamim M. Hosne M. , Ng Tien Khee , Ooi Boon S. , Khan M. Z. M.
Published: September 2020

Single and two-stage self-injection locking in InGaN/GaN laser diode is presented. Near single-mode emission with 34pm linewidth, and simultaneous locking of four longitudinal modes with appreciable 18dB SMSR and <2.5dB peak power ratio is achieved.
Reduction of Effective Pixel Pitch of Digital Micromirror Device for Lidar Transmitter and Receiver
Authors: Luo Chuan , Hellman Brandon , Chen Guanghao , Rodriguez Joshua , Jimenez Diego , Perkins Charles , Park Jae-Hyeung , Akoglu Ali , Takashima Yuzuru
Published: September 2020

Small pixel pitch with a large array size is highly anticipated for solid-state lidar transmitter and receiver. We demonstrate 2D beam steering with reduced effective pixel pitch by harnessing transitional state of the mirror array.
2D Material based Electro-Absorption Modulator in Si Photonics
Authors: Maiti Rishi , Ti Xie , Wang Hao , Amin Rubab , Patil Chandraman , Sorger Volker J.
Published: September 2020

Here, we demonstrate an efficient electro-absorption modulator (EAM) based on few-layered MoTe2 into a silicon photonics platform for the 1st time. The modulator exhibits an extinction ratio of ~0.1dB/m at 1310 nm.
Three-Dimensional Hyperspectral Imaging with Femtosecond Laser-Induced Filamentation
Authors: Wang Xiaoyue , Yan Ming , Yuan Shuai , Nan Junyi , Ren Xinyi , Wang Yinqi , Zeng Heping
Published: September 2020

We explore the potential of femtosecond laser-induced filamentation for optical gas imaging. In a proof-of-concept experiment, non-contact three-dimensional hyperspectral imaging of an alcohol/air flame is demonstrated with high spatial and spectral resolution.
Polarization Bistable Single Fundamental Mode Photonic Crystal VCSELs
Authors: Wang Qiuhua , Xie Yiyang , Xu Chen , Pan Guanzhong , Dong Yibo
Published: September 2020

The polarization bistable (PB) single fundamental mode VCSEL was realized by using dual mode confinement microstructure, rhombus shape-oxide aperture and photonic crystal. As the injection current increasing, the device polarization direction has been changed.
Photonic Neural Activation Function Using An ITO Electro-Absorption Modulator
Authors: Amin Rubab , George Jonathan , Maiti Rishi , Miscuglio Mario , Sorger Volker J.
Published: September 2020

We demonstrate an ITO-based electro-absorption modulator monolithically integrated into silicon photonics as nonlinear activation function of a photonic neuron. The synapse and neuron circuit executes a 200-node MNIST neural network benchmarking the nonlinear activation function.
Laser Rack Systems for Quantum Technologies
Authors: Rohde Felix , Neuhaus Rudolf , Ritter Stephan , Falke Stephan , Eismann Ulrich , Kienle Florian , Brakhane Stefan , Heizenreder Benedikt , Horvath-Klein Ruben , Stuhler Jürgen
Published: September 2020

We report on our development of laser rack systems as “quantum enabling” building blocks of future quantum devices. We present funded projects, where such rack laser systems are integrated into first prototypes.
Design and fundamental limits of nearfield magnetic-force scanning microscopy via the no-cloning theorem
Authors: Nemirovsky Jonathan , Mechel Chen , Cohen Eliahu , Kaminer Ido
Published: September 2020

We analyze nearfield measurements of magnetic fields originating from quantum sources and measured by quantum probes. We show that cloning-inspired techniques reveal optimal measurement schemes and new universal precision bounds for nearfield detectors.
Nanoscale ultrathin glass cantilevers for quantum sensing
Authors: Sidhu Mehra S. , Singh Kamal P.
Published: September 2020

We fabricated ultra-thin glass cantilevers using femtosecond laser pulses while integrating nitrogen vacancy (NV) centers at its tip. The magneto-optical susceptibility of NV centers towards electron spin was exploited for quantum sensing applications.
Solar powered fiber laser for energy conversion applications
Authors: Masuda T. , Dottermusch S. , Howard I. A. , Richards B. S. , Bisson J. , Endo M.
Published: September 2020

We demonstrate a solar-powered laser (SPL) that does not rely on any concentrator optics or solar tracking system. We believe that the utility of such “unconcentrated” SPLs has considerably increased for energy conversion applications. The proposed SPL consists of a Nd3+-doped fiber as an active medium, a liquid sensitizer, and a housing in which the transmittance of the front window is tailored to work as a luminescent solar collector. The very simple structure of the proposed SPL can be mass-produced easily at a low cost. The lasing threshold is 0.07 W/cm2 (70% of natural sunlight) which is four orders of magnitude smaller than those of conventional SPLs, and the output power at the pumping intensity of 0.1 W/cm2 is 0.25 mW. The SPL exhibits several lasing peaks between 1095 and 1105 nm.
Antibiotic Selection for Resistant Bacteria Infecting Living Tissue using Biodynamic Imaging
Authors: Choi Honggu , Zuponcic Jessica , Ximenes Eduardo , Ladisch Michael , Turek John , Nolte David
Published: September 2020

Misuse of antibiotics causes bacteria to develop antibiotic-resistance. Biodynamic imaging (BDI) of living tissue infected by E. coli detects antibiotic resistance and sensitivity by treating bacterial infections with antibiotics in vitro.
Flexible and robust detection of a remotely rotating target using fiber-guided orbital angular momentum superposed modes
Authors: Wan Zhenyu , Liang Yize , Fang Liang , Wang Jian
Published: September 2020

We propose and experimentally verify a flexible and robust rotational Doppler velocimetry for detecting a remotely rotating target in situ, which uses a ring-core fiber that can stably transmit the orbital angular momentum superposed modes.
Label-Free Super-Resolution Imaging of Mitochondria Structure of the Mouse Muscles with Photothermal Microscopy
Authors: Kobayashi Takayoshi , Nakata Kazuaki , Tanaka Hiroki , Kano Yutaka
Published: September 2020

Label-free photothermal microscopy with super-resolution was developed to investigate mouse brains, skin sections and unstained mouse muscle fibers. Continuous structural changing process of muscle fibers and mitochondria during and after muscle training was clearly resolved.
Digitally Calibrated Dual-comb Spectrometer for Open-air Gases Detection
Authors: Chen Xinyi , Zhang Weipeng , Li Yan , Wei Haoyun
Published: September 2020

Atmospheric gas sensing of a 200 m open path has been achieved by a digitally calibrated dual-comb spectrometer. A spectrum spanning over 10 THz has been obtained with a residual of less than 2%.
A Wearable Optical Fiber Wristband for Continuous and Accurate Blood Pressure Monitoring
Authors: Li Liangye , Li Yanpeng , Yang Liuyang , Fang Fang , Sun Qizhen
Published: September 2020

We present a wearable blood pressure wristband based on optical fiber probe with composite diaphragm. Clinical results show errors of systolic pressure and diastolic pressure are 0.24 ± 2.32 mmHg and 0.18 ± 2.48 mmHg.
Computational sensing with a multiplexed vertical flow assay for high-sensitivity C-Reactive protein quantification
Authors: Ballard Zachary S. , Joung Hyou-Arm , Goncharov Artem , Liang Jesse , Nugroho Karina , Di Carlo Dino , Garner Omai B. , Ozcan Aydogan
Published: September 2020

We demonstrate computational sensing with a multiplexed paper-based point-of-care assay for high sensitivity C-Reactive protein testing (hsCRP). Using blindly-tested human serum samples, we achieved an R2 value of 0.95 and an average coefficient-of-variation of 11.2%.
Fourier-plane Vortex Laser Holography for Robust, Small-brain Machine Learning and Image Classification
Authors: Mumimov Baurzhan , Vuong Luat T.
Published: September 2020

We show that the optical vortex illumination of objects undergoing diffraction performs simultaneous corner detection and image compression to be exploited in machine learning applications immune to adversarial attacks and robust to background noise.
Lithium Niobate Resonant Photoelastic Modulator for Time-of-Flight Imaging
Authors: Atalar Okan , Van Laer Raphael , Sarabalis Christopher J. , Safavi-Naeini Amir H. , Arbabian Amin
Published: September 2020

We demonstrate the working principle of a lithium niobate resonant photoelastic modulator. The optomechanical device can be integrated with a standard image sensor to convert it into a time-of-flight imaging system.
Elemental Mapping of Paraffin-Embedded Ductal Carcinoma Using Laser-Induced Breakdown Spectroscopy
Authors: Li Xiaohui , Chen Xue , Zhang Yao , Yang Sibo , Yao Guodong , Liu Aichun , Yu Xin
Published: September 2020

We present multi-elemental mapping of paraffine-embedded ductal carcinoma tissues using laser-induced breakdown spectroscopy (LIBS). Distributions of major elements (Ca, K, Mg, Na) were obtained. Automatic discrimination of malignant and non-malignant regions was achieved using cluster analysis.
One-Picosecond High-Energy Pulses in Edge-Emitting Laser Devices
Authors: Boiko Dmitri L.
Published: September 2020

Two approaches to get one-picosecond pulses on hundred pJ pulse energy scale from edge-emitting lasers are reported. One approach is based on very long tapered mode-locked lasers. The second utilizes short cavities in superradiance regime.
Full-Color MicroLEDs for Display Technologies
Authors: Bui Ha Quoc Thang , Velpula Ravi Teja , Jain Barsha , Nguyen Hieu Pham Trung
Published: September 2020

Red, green, and blue InGaN/AlGaN nanowire micro-light-emitting diodes (pLEDs) grown on a silicon substrate by molecular beam epitaxy with diameters from 20 to 100pm present stable emissions in the visible spectra, promising for microLED displays.
A metalens-based virtual reality (VR) / augmented reality (AR) system
Authors: Li Zhaoyi , Lin Peng , Huang Yao-Wei , Park Joon-Suh , Chen Wei Ting , Shi Zhujun , Cheng Ji-Xin , Capasso Federico
Published: September 2020

We demonstrated a large and RGB-achromatic metalens by novel design methods. Furthermore, we realized a compact platform for a virtual reality / augmented reality system based on an RGB metalens and a fiber scanning display.
Precision Spectroscopy of N2O with a Cross-Dispersed Spectrometer and Mid-Infrared Frequency Comb
Authors: Bailey D. Michelle , Zhao Gang , Fleisher Adam J.
Published: September 2020

A two-dimensional dispersive spectrometer achieves single element noise equivalent absorbance of 2.2 X 10-5 Hz-1/2, and resolves rovibrational lines for all singly-substituted stable isotopic variants of nitrous oxide near 4.5 pm.
Sulfur-Hyperdoped Silicon-Based Flexible Photodetector with Excellent Comprehensive Performance
Authors: Jin Xiaorong , Wu Qiang , Jia Zixi , Huang Song , Yao Jianghong , Xu Jingjun
Published: September 2020

The first free-standing flexible photodetector based on sulfur-hyperdoped ultrathin silicon is obtained by femtosecond laser processing. The device described here exhibits excellent comprehensive performance, which surpasses most values reported for flexible Si- based photodetectors.
Stable Polarization Entanglement based Quantum Key Distribution over Metropolitan Fibre Network
Authors: Shi Yicheng , Thar Soe Moe , Poh Hou Shun , Grieve James A. , Kurtsiefer Christian , Ling Alexander
Published: September 2020

Quantum key distribution with O-band polarization-entangled photons over deployed telecom fiber network is demonstrated. Liquid-crystal retarders are used to compensate for fiber birefringence induced errors and ensure stable operation.
Practical Nonlocal Dispersion Compensation of O-band Entangled Photons over 20 km Deployed Metropolitan Fiber
Authors: Grieve James A. , Ming Chua Rui , Shi Yicheng , Poh Hou Shun , Kurtsiefer Christian , Ling Alexander
Published: September 2020

Time-energy entangled photon pairs experience nonlocal dispersion compensation after propagation over multi-segment deployed telecommunications fiber. The preservation of tight timing correlations enables the use of broadband quantum light sources in existing metropolitan fiber networks.
Optical Isotope Analyzer for Subsurface Gases
Authors: Vakhtin Andrei B. , Bomse David S.
Published: September 2020

A Raman spectrometer for field measurement of isotope ratios of subsurface gases including nitrogen, oxygen and carbon dioxide is presented.
Laser-Induced Fluorescence for Element Detection during Laser Welding of Al to Cu Foils
Authors: Simonds Brian J.
Published: September 2020

The use of laser-induced fluorescence for detecting Cu in the vapor plume under laser welding conditions is investigated. It is found that LIF is sensitive enough to detect Cu even before mechanical joint formation. (This work of the U.S. Government is not subject to U.S. copyright.)
Developing a time-resolved acoustofluidic flow cytometer for FRET studies and near-infrared fluorescent protein development
Authors: Sambrano Jesus , Houston Jessica P.
Published: September 2020

We present a novel time-resolved acoustofluidic flow cytometer that will be capable of resolving heterogenous cell populations in FRET shrdies and screen for and enrich cells with near-infrared fluorescent proteins with higher quantum yields.
Self-Mixing Flow Sensor for Lung Surfactant Delivery
Authors: Milesi Ilaria , Ventura Lorenzo , Cavedo Federico , Dellaca Raffaele , Norgia Michele , Donati Silvano
Published: September 2020

Lack of lung surfactant in preterm newborns leads to respirator distress, a major cause of death. Non-invasive medical cares are developed, based on real time measurement of flow surfactant instilled in the newborn. We propose a new optical flow sensor based on selfmixing interferometr, and develop a dedicated prototype for measuring surfactant flow rate in a small diameter duct.
Fully room temperature bio-sensing using active microdisk fabricated by ink-jet printing method
Authors: Nasir Abdul , Mikami Yuya , Takagishi Taku , Yatabe Rui , Yoshioka Hiroaki , Vasa Nilesh J. , Oki Yuji
Published: September 2020

Fluorinated hyper branched polymer based active microdisk was fabricated by ink-jet printing method. The carboxyl functional group of the polymer was used for the biotinylation of microdisk and then adsorption characteristics of avidin were evaluated.
Deep Learning Structured Illumination Microscopy
Authors: Shterman Doron , Feinberg Gilad , Tsesses Shai , Blau Yochai , Bartal Guy
Published: September 2020

We propose a Deep Learning (DL) framework for reconstructing super-resolved images in structured illumination microscopy, which reduces the amount of raw data required for the reconstruction and allows real-time super resolution imaging.
Absorption Enhancement in Terahertz Photoconductive Antenna by Means of the Novel Types of Metamaterials
Authors: Gric Tatjana , Rafailov Edik
Published: September 2020

We numerically investigate terahertz photoconductive antenna based on optimized plasmonic nanostructures, stressing the stronger enhancement in case of transparent conducting oxide nanowires. The case is treated by means of local and nonlocal effective medium approximations.
Progress in Superconducting Optoelectronic Networks for Neuromorphic Computing
Authors: Buckley S. M. , Chiles J. T. , McCaughan A. N. , Tait A. N. , Mirin R. P. , Nam S. W. , Shainline J. M.
Published: September 2020

We have proposed a superconducting opto-electronic platform for neuromorphic computing utilizing semiconductor light sources coupled to integrated waveguides for communication, and superconducting detectors and electronics for efficient computation. Here we summarize the recent experimental progress.
Reconfigurable Non-volatile High-performance Metalens
Authors: Shalaginov Mikhail , An Sensong , Zhang Yifei , Yang Fan , Su Peter , Liberman Vladimir , Chou Jeffrey , Roberts Christopher , Kang Myungkoo , Rios Carlos , Du Qingyang , Fowler Clayton , Agarwal Anuradha , Richardson Kathleen , Rivero-Baleine Clara , Zhang Hualiang , Hu Juejun , Gu Tian
Published: September 2020

We demonstrated a varifocal metalens based on the low-loss optical phase-change material Ge2Sb2Se4Tei (GSST). The lens features diffraction-limited performance and full 2n phase tuning range. Aberration- and crosstalk-free imaging using the lens was also demonstrated.
High-Dimensional Time-Frequency Entanglement and Schmidt Number Witnesses Using a Biphoton Frequency Comb
Authors: Chang Kai-Chi , Cheng Xiang , Sarihan Murat Can , Kumar Abhinav , Lee Yoo Seung , Zhong Tian , Gong Yan-Xiao , Xie Zhenda , Shapiro Jeffrey H. , Wong Franco N. C. , Wong Chee Wei
Published: September 2020

We demonstrated high-dimensional time-frequency entanglement with a mode-locked biphoton frequency comb. Hong-Ou-Mandel interference and joint spectral intensity measurements are performed, and we estimated Hilbert space dimensionality of at least 3481 via Schmidt mode decompositions.
Femtosecond Laser Fabricated Sensor Devices on SingleCrystal Sapphire Optical Fiber
Authors: Wang Mohan , Zhao Kehao , Huang Sheng , Yang Yang , Buric Michael , Ohodnicki Paul , Liu Bo , Chorpening Benjamin , Chen Kevin P.
Published: September 2020

We use the femtosecond laser direct writing technique to fabricate Rayleigh-scattering based distributed sensing and point sensing devices on single-crystal sapphire optical fiber. This technique can be potentially useful for harsh environment sapphire sensor integration.
Summary of modeling thermo-photo-voltaic selective emitter design based on theoretical semi-transparent materials with integrated pre-filter using Mie scattering spheres
Authors: Stake Frank
Published: September 2020

Theoretical study to improve Thermo-Photo-Voltaic (TPV) Selective Emitters (SE) based on specialized grey body dielectric materials by adding microstructures which work within the body of semi-transparent SEs to refine their surface output spectrum.
Azimuthally Apodized Focusing Gratings
Authors: Maharjan Rijan , Bohora Sanket , Hogg Richard , Childs David , Curry Richard , Crowe Iain , Dhakal Ashim
Published: September 2020

We experimentally show that azimuthally apodized circular gratings can allow light to penetrate further into the structure, and create a focus of ≈ 10 μm, allowing for biomedical applications such as OCT.
Two-soliton Microcombs Enabled Reconfigurable Microwave Photonic Filters
Authors: Hu Jianqi , He Jijun , Liu Junqiu , Raja Arslan S. , Karpov Maxim , Lukashchuk Anton , Kippenberg Tobias J. , Bres Camille-Sophie
Published: September 2020

We demonstrate reconfigurable microwave photonic filters based on two-soliton microcombs. The filter passbands can be reconfigured inherently via the various angles between two solitons of microresonator, without involving programmable pulse shapers.
Broadband fiber-to-chip coupling in different wavelength regimes realized by 3D-structures
Authors: Gehring Helge , Blaicher Matthias , Eich Alexander , Hartmann Wladick , Varytis Paris , Busch Kurt , Schuck Carsten , Wegener Martin , Pernice Wolfram H.P.
Published: September 2020

We present efficient coupling schemes based on direct-laser-writing to enable broadband interfacing of nanophotonic circuits to optical fibers. We demonstrate wide bandwidth coupling at both telecom and visible wavelengths.
Si-photonic integrated PZT thin film for acousto-optic modulation
Authors: Ansari Irfan , Van de Veire Tessa , George John P. , Feutmba Gilles.F. , Beeckman Jeroen , Van Thourhout Dries
Published: September 2020

We demonstrate optical phase modulation in a Si waveguide by generation of surface acoustic wave using Lead Zirconate T itanate (PZT) thin film. Our measurement shows a V*L ~ 3.35 V cm before any device-optimization.
Hybrid imaging-based beam steering system using a sparse photonic integrated circuit outcoupling array
Authors: Polkoo Sajad Saghaye , Renshaw Christopher Kyle
Published: September 2020

We introduce a sparse photonic integrated circuit outcoupling (PICO) array for use with fast steering mirrors in a hybrid imaging-based beam steering (IBBS) system for free-space optical communications and LIDAR applications.
Integrated Lithium Niobate Modulator and Frequency Comb Generator Based on Fabry-Perot Resonators
Authors: Xu Mengyue , He Mingbo , Liu Xiaoyue , Pan Ying , Yu Siyuan , Cai Xinlun
Published: September 2020

We achieve 40 Gb/s operation of a low-loss modulator and generation of an optical frequency comb with spacing of 16.3 GHz on lithium niobate on insulator platform. These devices are based on distributed Bragg reflectors.
Single microcavity with top grating for cylindrical vector beam lasing
Authors: Zheng Shuang , Ma Xiang , Chen Quanan , Lu Qiaoyin , Guo Weihua , Wang Jian
Published: September 2020

Based on InP platform, we design and optimize a compact integrated device to realize efficient lasing of azimuthally polarized beam. Single-mode selection, emission and high speed can be achieved under electrical pumping.
Wavelength-dependent third-harmonic generation in monolayer MoS2
Authors: Wang Yadong , Das Susobhan , Hu Xuerong , Dai Yunyun , Bai Xueyin , Sun Zhipei
Published: September 2020

We present broadband third harmonic generation (THG) in monolayer MoS2, showing strong enhancement (up to three orders of magnitude) with excitons. Our results pave the way to understand strong THG in MoS2 for potential applications.
A Mode Division Multiplexing Scheme Utilizing Accelerating Beams Constructed in Mixed Domain
Authors: Lin Shuqing , Wen Yuanhui , Chen Yujie , Zhang Yanfeng , Yu Siyuan
Published: September 2020

We design and experimentally demonstrate a system for mode-division multiplexing of accelerating plane wave beams, by combining light field control methods in line and frequency domains with reasonably arranged basic optical components.
Generation of broadband THz transients via metallic spintronic emitters driven by 20-fs pulses at 1030 nm
Authors: Weigel Alexander , Helms Leon , Buberl Theresa , Vogel Tim , Hofer Christina , Fritsch Kilian , Sabanés Natalia Martín , Jakob Gerhard , Kläui Mathias , Pronin Oleg , Kampfrath Tobias , Saraceno Clara , Pupeza Ioachim
Published: September 2020

We explore power and bandwidth scaling for the generation of highly-temporally-confined THz transients from spintronic emitters, driven by the 250-fs and 20-fs pulses of a high-power 28-MHz Yb-based laser, spectrally centered at 1030 nm.
Intrinsic anisotropy in nonlinear optical absorption of Sb2S3 nanorods
Authors: Yadav Rajesh Kumar , Adarsh K. V.
Published: September 2020

Here, we report the first observation of the fundamental intrinsic anisotropy (61%) in nonlinear absorption (NLA) of Sb2S3 nanorods. Experimentally, we found the anisotropy in NLA ΔIS (IS ┴-IS ǁ) ≈ 0.058GW/cm2 at a peak intensity 0.095GW/cm2.
Second-harmonic Generation of Asymmetric Bessel-Gaussian Beams Carrying Multiple OAM Charge Numbers
Authors: Dai Kunjian , Li Wenzhe , Morgan Kaitlyn S. , Miller J. Keith , Watkins Richard J. , Johnson Eric G.
Published: September 2020

In this paper we demonstrate the second-harmonic generation of asymmetric Bessel-Gaussian beams carrying orbital angular momentum. One advantage is that the asymmetric Bessel-Gaussian beams offer a chance to tailor the generated field.
Broadband absorption enhancement for InAsSb-based mid-infrared detection via photon-trapping structure
Authors: Suo Fei , Tong Jinchao , Zhang Dao Hua
Published: September 2020

We demonstrate an InAsSb-based mid-infrared detector via integrated photon-trapping hole array cavity structure, realizing 40% broadband absorption and 36% photocurrent enhancement in the wavelength range of 2 to 5 |xm.
On-Chip Compact Silicon-Based Polarizer with Ultra-Broad Bandwidth (>340 nm) by Sputtering Cadmium Oxide layers
Authors: Xu Yin , Hu Xin , Dong Yue , Zhang Bo , Ni Yi
Published: September 2020

We propose an on-chip compact silicon-based polarizer by sputtering multi-cadmium oxide layers on the silicon nanowire. The working bandwidth of higher than 340 nm is obtained in a short device length of 5 |xm.
Designing Ultra-Compact Silicon T-junctions using Machine Learning
Authors: Banerji Sourangsu , Hamrick Alex , Majumder Apratim , Menon Rajesh , Rodriguez Berardi Sensale
Published: September 2020

We designed an ultra-compact and low-loss T-junction via a reinforcement learning algorithm coupled with finite difference time domain (FDTD) simulations. Simulated insertion loss is < 1dB with a device footprint of 1.2 μm x 1.2 μm.
High-Q Dispersion-Engineered Si3N4 Microresonators Based on a Subtractive Processing Technique
Authors: Ye Zhichao , Twayana Krishna , Andrekson Peter A. , Torres-Company Victor
Published: September 2020

We demonstrate dispersion-engineered Si3N4 microresonators with mean Q values >10 million fabricated using standard subtractive techniques. Soliton microcombs at 100 GHz line spacing and mode-locked dark-pulse Kerr combs are reported.
Self improvement of Q-factor in a lithium tantalite microcavity with high optical damage threshold
Authors: Yan Xiongshuo , Liu Yian , Zhu Bing , Chen Yuping , Chen Xianfeng
Published: September 2020

A more than 500 mW input power enables about 2 /^W second harmonic light in a micron scale Lithium tantalite (LT) microcavity. The Q-factor has been improved from several 104 to 10 .
Far-field Optical Diffraction Imaging of Opal-based Photonic Crystal
Authors: Kumar Govind , Haldar Arpita , Vijaya R.
Published: September 2020

A bidirectional scattering distribution function with rigorous coupled-wave analysis is used to simulate the far-field diffraction pattern from opal-based photonic crystals. Experimental studies with monochromatic light provide a perfect correspondence with the simulation.
Waveform-Agile Frequency Doubled Laser System for Optical Switching and Characterization of Phase Change Materials at Near-IR Wavelengths
Authors: Sevison Gary A. , Burrow Joshua A. , Hendrickson Joshua R. , Sarangan Andrew , Agha Imad
Published: September 2020

We created a system for the characterization of Ge2Sb2Te5 starting with a 1550 nm CW laser and utilizing second harmonic generation through a PPLN crystal in order to achieve full pulse control at 775 nm.
Red-Emitting Carbon Dots for MicroLED Application
Authors: Liu Ye , Wu Bo , Tanyi Ekembu K , Cheng Li-Jing
Published: September 2020

We report 635 nm red-emitting carbon dots with a 230 nm Stokes shift, quantum yield more than 30%, and a wide UV- blue range excitation. We demonstrate the UV-curable carbon dot-embedded polymer for microLED application.
High-Q Ge-As-S Microring Resonators based on improved fabrication process for optical parametric amplifier
Authors: Zeng Pingyang , Xia Di , Yang Zelin , Zhang Bin , Sun Yaodong , Huang Yufei , Song Jingcui , Zhu Ying , Li Zhaohui
Published: September 2020

We experimentally demonstrate Ge-As-S resonators with intrinsic quality factor more than 1 million through a thermal annealing process (TAP). Preliminary result of optical parametric amplifier (OPA) in the ChG-based resonators can be observed.
Self-assembly of di-block copolymers for hyperbolic metasurfaces
Authors: Angelini Angelo , Murataj Irdi , Channab Marwan , Cara Eleonora , De Leo Natascia , Pirri Candido Fabrizio , Boarino Luca , Lupi Federico Ferrarese
Published: September 2020

We exploit directed self-assembly of di-block copolymers to obtain metal-dielectric nano-patterns over large area acting as hyperbolic meta-surface at visible wavelengths. We show that decay rate can be enhanced when spontaneous emitters are thereon located.
Broadband, High-Speed, and Extraordinarily Large All-Optical Switching with Yttrium-doped Cadmium Oxide
Authors: Saha Soham , Diroll Benjamin T. , Shank Joshua , Kudyshev Zhaxylyk , Dutta Aveek , Chowdhury Sarah Nahar , Luk Ting Shan , Campione Salvatore , Schaller Richard D. , Shalaev Vladimir M. , Boltasseva Alexandra , Wood Michael G.
Published: September 2020

We demonstrate significant epsilon-near-zero point shifts (11.3 pm to 5.3 pm), extraordinarily large (135%) optically-induced reflection modulation with picosecond response times, and carrier relaxation time-engineering in cadmium oxide via Yttrium doping.
Non-trivial optical force predictions for coupled waveguides depend on choice of stress tensor
Authors: Fernandes Thales , de Assis Pierre-Louis
Published: September 2020

Many stress tensors have been proposed to calculate optical forces in dielectrics. We show analytically and verify numerically that loss of translation symmetry means they must disagree on predictions of non-trivial forces in coupled waveguides.
Plasmonic Sensor Using Double-Layered Stimuli-Responsive Polymer Gels for Multiplexed Detection of Multiple Analytes
Authors: Mundel H. , Wei M. , Serpe M. J. , Aitchison J. S.
Published: September 2020

We present a proof-of-concept for a double-layered plasmonic biosensor using stimuli-responsive polymers. The relative change of each SPR and P^ peak are decoupled to identify how much each microgel layer reacts to a given stimulus.
Synthesis of TiN Nanoparticles by Pulsed Laser Ablation for Photothermal and Photodynamic Therapy
Authors: Xu Xiaohui , Dutta Aveek , Sivasubramaniam Badhu P. , Kholikov Khomidkhodzha , Shalaev Vladimir M. , Wei Alexander , Boltasseva Alexandra
Published: September 2020

Spherical titanium nitride (TiN) nanoparticles (NPs) (<50 nm) demonstrating high quality plasmon resonances are synthesized from commercially available much larger TiN NPs using pulsed laser ablation with an 800 nm femtosecond laser.
Strong coupling in a ID plasmonic-exciton hybrid systems
Authors: Yu Min-Wen , Ishii Satoshi , Li Shisheng , Ku Ji-Ren , Yang Jhen-Hong , Su Kuan-Lin , Taniguchi Takaaki , Nagao Tadaaki , Chen Kuo-Ping
Published: September 2020

A Rabi splitting of 90 meV at room temperature is estimated from monolayer M0S2 coupled to plasmonic gold nanogrooves which was confirmed by the photoluminescent enhancement, Kelvin probe force microscope scanning, and fluorescence lifetime measurement
Verification of Signal-to-Crosstalk Measurements for WDM Fiber Optical Parametric Amplifiers
Authors: Szabö Àron D. , Ribeiro Vitor , Gordienko Vladimir , Ferreira Filipe , Gaur Chandra , Doran Nick
Published: September 2020

Gaussian distribution of nonlinear inter-channel crosstalk noise is numerically shown in fiber optical parametric amplifiers with over 16 dB gain. Confidence of signal-to-crosstalk power ratio measurements is justified by consistency with error vector magnitude calculations.
Free-Space Adaptive Optical Communication Systems Against Atmospheric Turbulence and Device Vibrations
Authors: Liang Yize , Su Xinzhou , Wang Lulu , Wang Jian
Published: September 2020

We experimentally demonstrate an adaptive free-space optical (FSO) communication system against atmospheric turbulence and device vibrations. BER of 10-Gbaud 16-QAM signal transmission is measured under different transmitted power, showing ~8dB penalty improvement with the adaptive system.
Reinforced Virtual Network Function Chain Deployment in Elastic Optical Networks for Edge Computing
Authors: Zhu Ruijie , Wang Peisen , Li Shihua , Li Lulu , Samuel Aretor , Zhao Yongli
Published: September 2020

A reinforced virtual network function chain deployment algorithm is proposed in elastic optical networks for edge computing. Simulation results show that it can achieve lower blocking probability compared to state-of-art algorithms.
Novel Digital and Analogue Hybrid Radio over Fibre System for Distributed Antenna System (DAS) Fronthaul Applications
Authors: Li Tongyun , Yang Yumeng , Crisp Michael , White Ian H. , Penty Richard V.
Published: September 2020

A hybrid digital and analogue radio over fibre (RoF) architecture carrying WCDMA and LTE services with data compression at the digital path is demonstrated. Over 40dB dynamic range is achieved for both services.
Artificial Neural Network Assisted Demodulation for Directly Detected QAM Signals
Authors: Zhang Qiulin , Shu Chester
Published: September 2020

We propose an artificial neural network based demodulation block to mitigate the effect caused by signal to signal beating noise. Experimental results show that our proposed scheme outperforms Volterra equalizer assisted scheme.