bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparative Analysis of Italian Lettuce (Lactuca sativa L. var. ramose) Transcriptome Profiles Reveals the Molecular Mechanism on Exogenous Melatonin Preventing Cadmium Toxicity
Authors: Yu Xuena , Liang Le , Xie Yongdong , Tang Yi , Tan Huaqiang , Zhang Jianwei , Lin Lijin , Sun Bo , Huang Zhi , Liu Ji , Li Xiaomei , Tu Lihua , Li Huanxiu
Published: May 2022

Cadmium (Cd) accumulation in lettuce causes a large amount of yield loss during industry. Although many studies report that exogenous melatonin helps to alleviate the Cd stress of lettuce, the molecular mechanism for how plant tissue responds to Cd treatment is unclear. Herein, we applied both PacBio and Illumina techniques for Italian lettuce under different designed treatments of Cd and melatonin, aiming to reveal the potential molecular pathway of the response to Cd stress as well as the how the pre-application of exogenous melatonin affect this process. This result reveals that the root has the biggest expression pattern shift and is a more essential tissue to respond to both Cd and melatonin treatments than leaves. We reveal the molecular background of the Cd stress response in prospects of antioxidant and hormone signal transduction pathways, and we found that their functions are diverged and specifically expressed in tissues. We also found that candidate genes related to melatonin detoxify during Cd stress. Our study sheds new light for future research on how melatonin improves the cadmium resistance of lettuce and also provide valuable data for lettuce breeding.
Population Genetic Structure of Marine Leech, Pterobdella arugamensis in Indo-West Pacific Region
Authors: Azmey Syakirah , Taha Hussein , Mahasri Gunanti , Amin Muhamad , Habib Ahasan , Tan Min Pau , Arai Takaomi
Published: May 2022

Grouper aquaculture is rapidly expanding in both tropical and subtropical regions. The presence of marine leeches (Pterobdella arugamensis; previously named Zeylanicobdella arugamensis) infesting cultured groupers, however, can have a fatal effect on grouper aquaculture production and cause significant economic loss. Understanding the marine leech’s population structure is therefore important to determine its possible distributional origin and distributional mechanisms, which will help monitor and mitigate the infestation. In this study, a total of 84 marine leeches collected from cultured hybrid groupers Epinephelus spp. in Brunei Darussalam, Malaysia and Indonesia were identified as P. arugamensis, based on morphological and mitochondrial cytochrome c oxidase subunit I gene sequence analyses. These leech samples, together with additional sequences from the GenBank database, were grouped into four genetically distinct haplogroups: (1) Asia Pacific, (2) Borneo, (3) Surabaya and (4) Iran. The four populations were found to be highly diverged from each other. The results also suggested that the samples from the Asia Pacific population could be dispersed and transported from Indonesia.
A Logical Framework for Forensic DNA Interpretation
Authors: Hicks Tacha , Buckleton John , Castella Vincent , Evett Ian , Jackson Graham
Published: May 2022

The forensic community has devoted much effort over the last decades to the development of a logical framework for forensic interpretation, which is essential for the safe administration of justice. We review the research and guidelines that have been published and provide examples of how to implement them in casework. After a discussion on uncertainty in the criminal trial and the roles that the DNA scientist may take, we present the principles of interpretation for evaluative reporting. We show how their application helps to avoid a common fallacy and present strategies that DNA scientists can apply so that they do not transpose the conditional. We then discuss the hierarchy of propositions and explain why it is considered a fundamental concept for the evaluation of biological results and the differences between assessing results given propositions that are at the source level or the activity level. We show the importance of pre-assessment, especially when the questions relate to the alleged activities, and when transfer and persistence need to be considered by the scientists to guide the court. We conclude with a discussion on statement writing and testimony. This provides guidance on how DNA scientists can report in a balanced, transparent, and logical way.
Phenotypic Expression of Known and Novel Hemoglobin A2-Variants, Hemoglobin A2-Mae Phrik [Delta 52(D3) Asp > Gly, HBD:c.158A > G], Associated with Hemoglobin E [Beta 26(B8) Glu > Lys, HBB:c.79G > A] in Thailand
Authors: Phasit Amphai , Panyasai Sitthichai , Mayoon Monthon , Jettawan Niphawan , Satthakarn Surada
Published: May 2022

The interactions of δ-globin variants with α- and β-thalassemia or other hemoglobinopathies cause complex thalassemic syndromes and potential diagnostic problems. Understanding the molecular basis and phenotypic expression is crucial. Four unrelated Thai subjects with second hemoglobin (Hb) A2 fractions were studied. A standard automated cell counter was used to acquire initial hematological data. Hb analysis was carried out by capillary electrophoresis (CE) and high-performance liquid chromatography (HPLC) assays. Globin gene mutations and haplotype were identified by appropriate DNA analysis. An allele-specific polymerase chain reaction method was developed to provide a simple molecular diagnostic test. Hb analysis revealed a Hb A2 variant in all cases. DNA analysis of the δ-globin gene identified the Hb A2-Melbourne [δ43(CD2)Glu > Lys] variant in combination with Hb E in three cases. Analysis of the remaining case identified a novel δ-Hb variant, namely Hb A2-Mae Phrik [δ52(D3)GAT > GGT; Asp > Gly], found in association with Hb E and α+-thalassemia, indicative of the as yet undescribed combination of triple heterozygosity of globin gene defects. An allele-specific PCR-based assay was successfully developed to identify this variant. The β-haplotype of the Hb A2 Mae-Phrik allele was strongly associated with haplotype [+ − − − − ± +]. This study advanced our understanding of the phenotypic expression of known and novel δ-Hb variants coinherited with other globin gene defects, routinely causing problems with diagnosis. Therefore, knowledge and recognition of this Hb variant and molecular assessments are crucial to improving diagnosis.
Assessment of Bidirectional Relationships between Leisure Sedentary Behaviors and Neuropsychiatric Disorders: A Two-Sample Mendelian Randomization Study
Authors: He Qian , Bennett Adam N. , Fan Beifang , Han Xue , Liu Jundong , Wu Kevin Chun Hei , Huang Ruixuan , Chan Juliana C. N. , Chan Kei Hang Katie
Published: May 2022

(1) Background: Increasing evidence shows that sedentary behaviors are associated with neuropsychiatric disorders (NPDs) and thus may be a modifiable factor to target for the prevention of NPDs. However, the direction and causality for the relationship remain unknown; sedentary behaviors could increase or decrease the risk of NPDs, and/or NPDs may increase or decrease engagement in sedentary behaviors. (2) Methods: This Mendelian randomization (MR) study with two samples included independent genetic variants related to sedentary behaviors (n = 408,815), Alzheimer’s disease (AD; n = 63,926), schizophrenia (SCZ; n = 105,318), and major depressive disorder (MDD; n = 500,199), which were extracted from several of the largest non-overlapping genome-wide association studies (GWASs), as instrumental variables. The summarized MR effect sizes from each instrumental variable were combined in an IVW (inverse-variance-weighted) approach, with various approaches (e.g., MR-Egger, weighted median, MR-pleiotropy residual sum and outlier), and sensitivity analyses were performed to identify and remove outliers and assess the horizontal pleiotropy. (3) Results: The MR evidence and linkage disequilibrium score regression revealed a consistent directional association between television watching and MDD (odds ratio (OR), 1.13 for MDD per one standard deviation (SD) increase in mean television watching time; 95% CI, 1.06–1.20; p = 6.80 × 10−5) and a consistent relationship between computer use and a decrease in the risk of AD (OR, 0.52 for AD per one SD increase in mean computer use time; 95% CI, 0.32–0.84; p = 8.20 × 10−3). In the reverse direction, MR showed a causal association between a reduced risk of SCZ and an increase in driving time (β, −0.016; 95% CI, −0.027–−0.004; p = 8.30 × 10−3). (4) Conclusions: Using genetic instrumental variables identified from large-scale GWASs, we found robust evidence for a causal relationship between long computer use time and a reduced risk of AD, and for a causal relationship between long television watching time and an increased risk of MDD. In reverse analyses, we found that SCZ was causally associated with reduced driving time. These findings fit in with our observations and prior knowledge as well as emphasizing the importance of distinguishing between different domains of sedentary behaviors in epidemiologic studies of NPDs.
Hereditary Thrombophilia in the Era of COVID-19
Authors: Badulescu Oana Viola , Sirbu Paul Dan , Filip Nina , Bordeianu Gabriela , Cojocaru Elena , Budacu Cristian Constantin , Badescu Minerva Codruta , Bararu-Bojan Iris , Veliceasa Bogdan , Ciocoiu Manuela
Published: May 2022

Thrombophilia, also called hypercoagulability or prothrombotic condition, usually reflects a certain imbalance that occurs either in the coagulation cascade or in the anticoagulation/fibrinolytic system. A similar imbalance may be induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Thrombotic complications are associated with multiorgan failure and increased mortality. In this context, activation of coagulation and thrombocytopenia appeared as prognostic markers in COVID-19. Our work provides a structured and updated analysis of inherited thrombophilia and its involvement in COVID-19, emphasizing the importance of diagnosing and initiating thromboprophylaxis. Since the state of hypercoagulation is directly correlated with COVID-19, we consider that studies on the genetic profiles of proteins involved in thrombophilia in patients who have had COVID-19 and thrombotic events are of great importance, both in treating and in preventing deaths due to COVID-19.
Reductive Soil Disinfestation Enhances Microbial Network Complexity and Function in Intensively Cropped Greenhouse Soil
Authors: Yan Yuanyuan , Wu Ruini , Li Shu , Su Zhe , Shao Qin , Cai Zucong , Huang Xinqi , Liu Liangliang
Published: May 2022

Reductive soil disinfestation (RSD) is an effective practice to eliminate plant pathogens and improve the soil microbial community. However, little is known about how RSD treatment affects microbial interactions and functions. Previous study has shown that RSD-regulated microbiomes may degenerate after re-planting with former crops, while the effect of planting with different crops is still unclear. Here, the effects of both RSD treatment and succession planting with different crops on microbial community composition, interactions, and functions were investigated. Results showed that RSD treatment improves the soil microbial community, decreases the relative abundance of plant pathogens, and effectively enhances microbial interactions and functions. The microbial network associated with RSD treatment was more complex and connected. The functions of hydrocarbon (C, H), nitrogen (N), and sulfur (S) cycling were significantly increased in RSD-treated soil, while the functions of bacterial and fungal plant pathogens were decreased. Furthermore, the bacterial and fungal communities present in the RSD-treated soil, and soil succession planted with different crops, were found to be significantly different compared to untreated soil. In summary, we report that RSD treatment can improve soil quality by regulating the interactions of microbial communities and multifunctionality.
Trust in the Police during the Pro-Democracy Movement in Hong Kong: Psychosocial Factors of Perceived Procedural and Distributive Justice
Authors: Chan Heng Choon (Oliver)
Published: May 2022

Hong Kong has experienced social unrest in response to the proposed anti-extradition bill since early June 2019. Demonstrations and rallies have often ended in violent clashes between protestors and the police. Based on a sample of 1024 Hong Kong adults, this study explored the psychosocial factors underlying public perceptions of police procedural and distributive justice among Hong Kongers. Testing the propositions of several criminological theories (i.e., neutralization theory, the general aggression model, general strain theory, and self-control theory), the findings indicated that men reported significantly more positive general perceptions of police procedural and distributive justice, better general mental health, and more negative attitudes toward violence than women did. Young adults perceived significantly higher levels of police general, procedural, and distributive justice than did their middle-aged and older counterparts, who reported significantly better general mental health and greater self-control. Multivariate analyses indicated that across all age groups, better general mental health, greater self-control, and more negative attitudes toward violence were significantly associated with positive perceptions of police general, procedural, and distributive justice. This study concludes with practical guidance for enhancing public perceptions of police procedural and distributive fairness.
Treatment Adherence and Health-Related Quality of Life in Patients with Hemophilia in Hong Kong
Authors: Cheung Yin Ting , Lam Pok Hong , Lam Henry Hon Wai , Ma Chung-Tin , Leung Alex Wing Kwan , Wong Raymond Siu Ming , Li Chi Kong
Published: May 2022

Background: This study aims to identify factors affecting health-related quality of life (HRQoL) in Chinese patients with hemophilia in Hong Kong, and to examine the association between treatment adherence and HRQoL outcomes. Methods: Patients with hemophilia A or B from a non-governmental organization reported their HRQoL and treatment adherence to prophylactic therapy using validated tools. Univariate tests and multivariable regression analysis were used to compare differences in outcomes across clinically relevant subgroups. Results: Fifty-six patients were recruited (mean age 30.4 [17.4] years; majority hemophilia A: 75%; moderate-to-severe severity: 88%). Patients who received prophylactic treatment reported fewer work/school problems (25.8 [18.9] versus 51.5 [26.3]; p = 0.001) than those who received on-demand therapy. The multivariable model showed that older age (B = 0.42, 95% CI = 0.093–0.75) and living in public housing (B = 10.24, 95% CI = 0.70–19.77) were associated with worse HRQoL. Older age was associated with treatment non-adherence (r = 0.66, p < 0.0001). Patients with poor adherence tended to report worse functioning in sports/leisure (r = 0.31, p = 0.033). Conclusions: Our results suggest that patients who were older, had lower education attainment and received on-demand treatment had poorer perception of their health. Improving adherence may lead to better HRQoL. Future work includes evaluating the occupational needs prospectively in this population.
A Systematic Review and Meta-Analysis of Systemic Antibiotic Therapy in the Treatment of Peri-Implantitis
Authors: Toledano-Osorio Manuel , Vallecillo Cristina , Toledano Raquel , Aguilera Fátima S. , Osorio María T. , Muñoz-Soto Esther , García-Godoy Franklin , Vallecillo-Rivas Marta
Published: May 2022

Research has been conducted into the advantages of the systemic administration of antibiotics. The aim of this systematic review and meta-analysis was to assess the efficacy of systemic antibiotic administration in the treatment of peri-implantitis in terms of bleeding on probing (BoP) and probing pocket depth (PPD). Literature searches were performed across PubMed, EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL) to identify randomized controlled trials and observational clinical studies. After peri-implantitis treatment, PPD was reduced by 0.1 mm (p = 0.58; IC 95% [−0.24, 0.47]), indicating a non-significant effect of antibiotic administration on PPD. The BoP odds ratio value was 1.15 (p = 0.5; IC 95% [0.75, 1.75]), indicating that the likelihood of bleeding is almost similar between the test and control groups. Secondary outcomes were found, such as reduced clinical attachment level, lower suppuration and recession, less bone loss, and a reduction in total bacterial counts. In the treatment of peri-implantitis, the systemic antibiotic application reduces neither PPD nor BoP. Therefore, the systemic administration of antibiotics, in the case of peri-implantitis, should be rethought in light of the present results, contributing to address the problem of increasing antibiotic resistance.
Association between Daily Pattern of Physical Activity and Depression: A Systematic Review
Authors: Gianfredi Vincenza , Ferrara Pietro , Pennisi Flavia , Casu Giulia , Amerio Andrea , Odone Anna , Nucci Daniele , Dinu Monica
Published: May 2022

Recent research suggested that daily pattern of physical activity (PA) may have an important association with depression, but findings are limited and contradictory. Our aim was to conduct a systematic review of the literature to summarize the literature evidence on the association between timing of PA and depression. A comprehensive search of PubMed/Medline and Scopus databases has been performed, and a total of five manuscripts have been thoroughly reviewed. The performed descriptive analysis shows lower levels of PA among individuals with depression or depressive symptoms, although evidence on the 24 h pattern of PA and depression is limited. An interesting finding is the association between lower PA during the morning, higher PA late in the evening (night), and depression or depressive symptoms. However, definitive conclusions could not be drawn due to the observational nature of the studies, their limited number, the high heterogeneity in the sample populations, and the studies’ differing outcome definitions and exposure assessments. Future studies considering not only the level of PA but also its daily variability might be important to further explore this novel area of research.
Exposure to Chloramine and Chloroform in Tap Water and Adverse Perinatal Outcomes in Shanghai
Authors: Zhu Si-Meng , Li Cheng , Xu Jing-Jing , Zhang Han-Qiu , Su Yun-Fei , Wu Yan-Ting , Huang He-Feng
Published: May 2022

Chloramine and chloroform are widespread in tap water due to water disinfection processes. This study was designed to explore the associations between trimester-specific exposure to chloramine and chloroform in tap water and adverse outcomes. This retrospective cohort study included 109,182 mother–infant singleton pairs in Shanghai. A logistic regression model was used to evaluate the associations of chloramine and chloroform concentrations averaged over the whole pregnancy and in each trimester with adverse outcomes, including gestational diabetes mellitus (GDM), gestational hypertensive disorders (GHD), low birthweight (LBW), small for gestational age (SGA), preterm birth (PTB) and prelabor rupture of membranes (PROM). The use of tap water with elevated chloramine levels in the first trimester was associated with GDM (OR = 1.06, 95% CI: 1.03, 1.09), while that in the second trimester was related to GHD (OR = 1.13, 95% CI: 1.09, 1.17). Chloroform levels in the third trimester were associated with LBW (OR = 1.13, 95% CI: 1.09, 1.16), PTB (OR = 1.05, 95% CI: 1.01, 1.08) and PROM (OR = 1.01, 95% CI: 1.00, 1.01). However, tap water chloroform exposure in the second trimester was negatively associated with LBW (OR = 0.95, 95% CI: 0.93, 0.98) and PTB (OR = 0.97, 95% CI: 0.94, 0.99). In conclusion, there are probably no casual associations between current tap water chloroform and chloramine levels and perinatal outcomes. However, more research focusing on the effect of chloramine and chloroform on perinatal outcomes are still warranted.
Food Waste Management Practices and Barriers to Progress in U.S. University Foodservice
Authors: Musicus Aviva A. , Amsler Challamel Ghislaine C. , McKenzie Robert , Rimm Eric B. , Blondin Stacy A.
Published: May 2022

Identifying institutional capacity to reduce and reallocate food waste is important to reduce both greenhouse gas emissions and food insecurity. The goal of this study was to examine food waste concern, reduction and repurposing strategies, and perceived barriers to these strategies among U.S. university foodservice representatives. We surveyed 57 U.S. university foodservice representatives about foodservice operations, campus food insecurity, food waste reduction and repurposing activities, and obstacles to composting and donating food waste. Data were collected September 2019–February 2020. Roughly three-quarters of respondents tracked campus food waste, reported that food waste reduction was a high/very high priority, and reported concern about campus food insecurity. The most common food-waste-reduction strategies included forecasting demand to prevent overproduction and preparing smaller batches. The most common repurposing strategies included donation and composting. Top barriers to food donation included liability concerns and lack of labor. Barriers to composting food included lack of infrastructure and knowledge/experience. Addressing perceived barriers to university foodservices’ food waste reduction and repurposing efforts could lead to reduced greenhouse gas emissions and improved food security for millions of Americans.
Promoting Older Adult Health with Interprofessional Education through Community Based Health Screening
Authors: Ostertag Susan , Bosic-Reiniger Jade , Migliaccio Chris , Zins Rachael
Published: May 2022

IPHARM (ImProving Health Among Rural Montanans) is a university-based community health screening program that provides valuable interprofessional teamwork and clinical skills training for health care students while addressing the health of older adults. Students perform a variety of health care screenings dependent on the health care professions present and the requests of the community group served. Education, counseling, and recommendations for participants are provided by the interprofessional student teams under supervision and guidance from faculty and clinicians. Supported in part by federal grants such as the Health Service and Resource Administration Geriatric Workforce Enhancement Program (HRSA GWEP), IPHARM has provided interprofessional training for over 2100 students and conducted over 30,000 health screenings at 814 different community events. Surveys from students indicate that the experience promotes effective interprofessional team skills related to communication, an increased understanding of the roles and responsibilities of the health care team, and how to positively impact the health of older adults. These interprofessional screening events for older adults, conducted in the community by health professions students and faculty, help prepare the future workforce for collaborative and effective health care delivery. The purpose of this article is to describe the IPHARM objectives, methods, and impact this program has had on the health of older adults and the training of our future health care workforce.
Postnatal Depression and Post-Traumatic Stress Risk Following Miscarriage
Authors: Kukulskienė Milda , Žemaitienė Nida
Published: May 2022

The experience of miscarriage is an important population-level problem that affects approximately 10–25% of pregnancies. The physical consequences of miscarriage have been researched extensively, but psychological sequelae less so. First-person accounts show that women who have experienced miscarriage feel pressured to stay silent, to grieve, and to fight intense physical and psychological challenges alone. There is ample scientific evidence on the links between miscarriage and physical and mental health disorders, such as complicated grief, anxiety, depression, post-traumatic stress, suicidal risk, psychosomatic disorders, sexual health disorders, etc. However, there is a lack of deeper understanding of the specifics of psychological morbidity after miscarriage, as well as of the information on vulnerability and resilience factors. This study aims to assess the risk of postnatal depression and post-traumatic stress following miscarriage. A total of 839 Lithuanian women who had one or more miscarriages were asked to complete an online questionnaire, including the Edinburgh Postnatal Depression Scale (EPDS) and the Impact of Events Scale-Revised (IES-R). Of the women, 59.1% were found to be at increased risk of postnatal depression and 48.9% at high risk of postnatal depression; 44.7% of the women were considered to be at increased risk of post-traumatic stress. An impaired relationship with one’s body and childlessness has been the strongest predictors of psychological morbidity risk.
Influence of E-Cigarette and Cannabis Vaping on Orthodontically Induced Tooth Movement and Periodontal Health in Patients Undergoing Orthodontic Therapy
Authors: Michelogiannakis Dimitrios , Rahman Irfan
Published: May 2022

The frequency of e-cigarette vaping of nicotine and marijuana products is increasing among adolescents and young adults; the detrimental effects of vaping on general and oral health have not yet been thoroughly defined [...]
Acute Kidney Failure among Brazilian Agricultural Workers: A Death-Certificate Case-Control Study
Authors: Meyer Armando , Santos Aline Souza Espindola , Asmus Carmen Ildes Rodrigues Froes , Camara Volney Magalhaes , Costa Antônio José Leal , Sandler Dale P. , Parks Christine Gibson
Published: May 2022

Recent evidence suggests that pesticides may play a role in chronic kidney disease. However, little is known about associations with acute kidney failure (AKF). We investigated trends in AKF and pesticide expenditures and associations with agricultural work in two Brazilian regions with intense use of pesticides, in the south and midwest. Using death certificate data, we investigated trends in AKF mortality (1980–2014). We used joinpoint regression to calculate annual percent changes in AKF mortality rates by urban/rural status and, in rural municipalities, by tertiles of per capita pesticide expenditures. We then compared AKF mortality in farmers and population controls from 2006 to 2014 using logistic regression to estimate odds ratios and 95% confidence intervals adjusted by age, sex, region, education, and race. AKF mortality increased in both regions regardless of urban/rural status; trends were steeper from the mid-1990s to 2000s, and in rural municipalities, they were higher by tertiles of pesticide expenditures. Agricultural workers were more likely to die from AKF than from other causes, especially at younger ages, among females, and in the southern municipalities. We observed increasing AKF mortality in rural areas with greater pesticide expenditures and an association of AKF mortality with agricultural work, especially among younger workers.
The Correlation between Organizational (School) Climate and Teacher Job Satisfaction—The Type of Educational Institution Moderating Role
Authors: Otrębski Wojciech
Published: May 2022

The quality of work and task implementation in educational institutions to a large extent depends on the personnel of those institutions. This is particularly true in the case of teaching pupils with special educational needs. The climate of education and learning and job satisfaction depend on teachers themselves. The purpose of this study was to verify the extent to which the type of educational institution (a mainstream or special school) moderates the correlation between teachers’ subjective evaluation of the organizational climate, their job satisfaction, and work-related emotions. The study involved 214 teachers representing all levels of school education in Poland, i.e., primary, middle, and high schools attended by pupils with special educational needs. Half of the teachers worked in mainstream schools and the other half—in special schools. The study used: The Organizational Climate Questionnaire by Litwin and Stringer; The Satisfaction with Job Scale; and The Work Affect Scale. The results clearly suggest that the teachers’ perception of the organizational climate is a strong predictor of their job satisfaction and work-related emotions. A positive climate is associated with high satisfaction and good emotions (enthusiasm and comfort) while a negative climate co-occurs with low satisfaction and bad emotions (anxiety and depression). The organizational type of institution (mainstream or special school) does not significantly affect the above predictive attribute of the organizational climate.
Exploring the Relationship among Human Activities, COVID-19 Morbidity, and At-Risk Areas Using Location-Based Social Media Data: Knowledge about the Early Pandemic Stage in Wuhan
Authors: Yuan Mengyue , Liu Tong , Yang Chao
Published: May 2022

It is significant to explore the morbidity patterns and at-risk areas of the COVID-19 outbreak in megacities. In this paper, we studied the relationship among human activities, morbidity patterns, and at-risk areas in Wuhan City. First, we excavated the activity patterns from Sina Weibo check-in data during the early COVID-19 pandemic stage (December 2019~January 2020) in Wuhan. We considered human-activity patterns and related demographic information as the COVID-19 influencing determinants, and we used spatial regression models to evaluate the relationships between COVID-19 morbidity and the related factors. Furthermore, we traced Weibo users’ check-in trajectories to characterize the spatial interaction between high-morbidity residential areas and activity venues with POI (point of interest) sites, and we located a series of potential at-risk places in Wuhan. The results provide statistical evidence regarding the utility of human activity and demographic factors for the determination of COVID-19 morbidity patterns in the early pandemic stage in Wuhan. The spatial interaction revealed a general transmission pattern in Wuhan and determined the high-risk areas of COVID-19 transmission. This article explores the human-activity characteristics from social media check-in data and studies how human activities played a role in COVID-19 transmission in Wuhan. From that, we provide new insights for scientific prevention and control of COVID-19.
Motivation Regarding Physical Exercise among Health Science University Students
Authors: Sánchez-Herrera Susana , Cubero Javier , Feu Sebastián , Durán-Vinagre Miguel Ángel
Published: May 2022

Physical exercise and physical activity are inherent and essential agents in the evolution of active life and are associated with promoting health and well-being. This study aimed to examine the types of regulation of motivations and intentionality needed to be physically active in the future in university students from the Health Sciences branch of knowledge. Method: 351 university students with six university degrees in Health Sciences participated, 21.4% of whom were male and 78.6% women (M = 19.32; SD = 4.01). They answered the following questionnaires: “International Physical Activity Questionnaire (IPAQ)”, “Behavioural Regulation of Exercise Questionnaire (BREQ-3)”, and “Intention to be physically active (MIFAU)”. Results: intrinsic motivation and integrated regulation were positively associated (rho = 0.759; p < 0.01), as were integrated and identified codes (rho = 0.645; p < 0.01). When relating the types of motivation regulation and the intention to be physically active, men show a significant difference compared to women. It stands out that physically active people who walk are the most unmotivated (p < 0.01). Conclusions: more self-determined regulations and intentionality to be physically active are related to different physical activity levels and the number of METs.
Latent Occupational Burnout Profiles of Working Women
Authors: Załuski Maciej , Makara-Studzińska Marta
Published: May 2022

According to scientific research, emergency call-takers and dispatchers (ECD) are particularly vulnerable to burnout syndrome. It can be observed that this occupation is predominantly performed by women. Moreover, the studies on occupational burnout indicate its different causes depending on employees’ gender. The aim of this research was to apply a Person-Oriented approach in order to examine the relationships between particular risk factors, the level of burnout, and its health consequences in a group of women. A cross-sectional survey study was conducted on 296 women (call-takers and dispatchers) from public-safety answering points in Poland. The Link Burnout Questionnaire and a sociodemographic questionnaire were used to gather information. The method of latent profile analysis (LPA) was employed in the study. The study revealed burnout patterns without full symptoms as well as four different burnout profiles. The findings partially confirmed initial assumptions about correlations between the length of service as ECD, marital status, motherhood, burnout symptoms, and body mass index (BMI). Sociodemographic variables differentiated the examined women in terms of their emotional exhaustion and BMI. Three groups of women at risk of burnout and overweight were identified: those with the shortest job experience, those with the longest job experience, and an intermediate group. In each of these groups, symptoms indicating a possible risk of burnout-related health issues could be observed. The application of a Person-Oriented approach allowed for assessing possible correlations between burnout risk factors, its symptoms, and health consequences.
Influencing Factors on the Household-Waste-Classification Behavior of Urban Residents: A Case Study in Shanghai
Authors: Tang Decai , Shi Lei , Huang Xiaojuan , Zhao Ziqian , Zhou Biao , Bethel Brandon J.
Published: May 2022

As the process of urbanization in China continues to accelerate, the amount of domestic waste generated correspondingly increases and directly affects the living space of residents. This indirectly implies that to reduce the production of municipal solid waste and the need for garbage disposal and recycling, household-waste-classification activities by the residents are of great significance. Using Shanghai as a case study, this study investigated the influencing factors on residents’ household waste classification by conducting a survey. Statistical analysis was then adopted, which is specified below. First, this study proposed research hypotheses related to the influencing factors of residents’ domestic-waste-sorting behavior from three levels: government, society and individuals. Second, the study designed a questionnaire from five perspectives: individual characteristic variables, government, society, residents and classification behavior. Then, SPSS software was used to carry out descriptive statistical, reliability and validity assessments using ANOVA, correlation and regression analyses on the sample data obtained from the questionnaire. The results suggested that the research hypotheses were statistically significant: (1) females and residents with higher education were more likely to participate in domestic waste classification; (2) reward and punishment measures had the most significant impact on residents’ waste-classification behavior; and (3) publicity and education, classification standards, classification facilities, the recycling system, subjective norms, environmental knowledge and environmental attitudes all had a positive effect on residents’ household waste classification. Finally, based on the results of the empirical analysis, this paper provides reference suggestions for the further development of domestic waste classification in Shanghai.
Characterization of Microbial Communities in Wastewater Treatment Plants Containing Heavy Metals Located in Chemical Industrial Zones
Authors: Zeng Taotao , Wang Liangqin , Zhang Xiaoling , Song Xin , Li Jie , Yang Jinhui , Chen Shengbing , Zhang Jie
Published: May 2022

Water pollution caused by heavy metals (HMs) poses a serious risk to human health and the environment and can increase the risk of diabetes, cancer, and hypertension in particular. In this study, two full-scale wastewater treatment plants (WWTPs) in industrial zones in southern China were selected to analyze the microbial community structure, diversity, similarity, and differentiation in the anoxic/oxic (AO) and anoxic/oxic membrane bioreactor (AO-MBR) units under the stress of HMs. High-throughput sequencing showed that microbial diversity and abundance were higher in the AO process than in the AO-MBR process. In the two WWTPs, the common dominant phyla were Proteobacteria and Bacteroidetes, while the common dominant genera were Gemmatimonadaceae, Anaerolineaceae, Saprospiraceae, and Terrimonas. Manganese (Mn) and zinc (Zn) positively correlated with Saccharimonadales, Nakamurella, Micrococcales, and Microtrichales, whereas copper (Cu) and iron (Fe) positively correlated with Longilinea and Ferruginibacter. Additionally, the relative abundances of Chloroflexi, Patescibacteria, and Firmicutes differed significantly (p < 0.05) between the two processes. These results may provide comprehensive outlooks on the characterization of microbial communities in WWTPs, which could also help to reduce the potential environmental risks of the effluent from WWTPs located in industrial zones.
Cancer Survivors in Saint Lucia Deeply Value Social Support: Considerations for Cancer Control in Under-Resourced Communities
Authors: Auguste Aviane , Cox Shania , Oliver JoAnn S. , Phillip Dorothy , Gabriel Owen , Catherine James , Radix Carlene , Luce Danièle , Barul Christine
Published: May 2022

Understanding the views of cancer survivors on their experience is important for informing community-based interventions. We studied, for the first time, the views of cancer survivors residing in Saint Lucia on their overall care experience. We used interview data from a cohort of adult cancer survivors from Saint Lucia between 2019 and 2020. We performed a thematic analysis to derive themes from codes. Forty-four survivors provided responses to at least one of the three questions. The majority of survivors were black, female and diagnosed with breast cancer. Survivors were interviewed on average five years after diagnosis. Four common themes emerged; “Availability of support groups”, “Importance of support from family and friends”, “Access to finances” and “Health education and patient navigation”. Travel overseas for health services was common among survivors. Survivors expressed emotional distress during travel due to isolation from family and local providers. This is typical among island populations and is distinct from existing patient frameworks. Survivors also suggested that networking amongst providers and interventions assisted families of cancer survivors. Although tertiary care services are limited, we showed that survivors deeply value and depend on their inter-personal relationships during care. Interventions aimed at strengthening the inter-personal environment of survivors are warranted.
Three-Questions-Method for Coping with the Emotional Burden of Nurses and Nursing Students during COVID-19
Authors: de Bot Cindy M. A. , de Vos Annemarie J. B. M.
Published: May 2022

Background: Nurses and nursing students experienced an emotional burden while working during the COVID-19 outbreak. During the COVID-19 outbreak three questions for nurses working under these extreme circumstances were formulated: 1. What today’s events do you remember? 2. How do you feel (physically and mentally)? 3. Do you have enough support? The purpose of this study was to obtain insight into whether nurses and nursing students perceive that the use of the three-questions-method contributes to effective coping with the emotional burden during the COVID-19 outbreak. Methods: Focus group interviews were held with hospital nurses (n = 11) and nursing students with internships in mental health care (n = 2), hospital (n = 9), and homecare/nursing home care (n = 3) in September 2020 followed by twenty semi-structured interviews one year later. Results: Almost all nurses and nursing students named factors that contributed to the emotional burden: fear, powerlessness, frustration, lack of knowledge about COVID-19, and pressure to pass the internship. Participants indicated that using the three-questions-method can help to effectively cope with the emotional burden during and after the COVID-19 outbreak. Conclusions: Using the three-questions-method offers added value in coping with emotional burden and can be used in education as well as in practice.
Enhanced Dewatering of Activated Sludge by Skeleton-Assisted Flocculation Process
Authors: Xia Jiahua , Rao Ting , Ji Juan , He Bijuan , Liu Ankang , Sun Yongjun
Published: May 2022

Sludge dewatering is the fundamental process of sludge treatment. Environmentally friendly and efficient sludge conditioning methods are the premises of sludge to achieve dehydration reduction and resource utilization. In response to sewage plant sludge dehydration, fly ash (FA), polymerized aluminum chloride (PAC), and polymer sulfate (PFS) were studied separately to determine their sludge dehydration performance, and the effects of these three conditioner composite regulations on sludge dehydration properties were studied. Compared to the sludge treated only with conditioner, the average particle size of floc increased and the organic matter content in the filtrate decreased. The sludge dewatering efficiency after the conditioning effect is better than that after conditioning a single conditioner. After PFS conditioning with fly ash, the water content and specific resistance (SRF) of the sludge cake can be reduced to 76.39% and 6.63 × 1010 m/kg, respectively. The moisture content and specific resistance (SRF) of the sludge cake can be reduced to 76.10% and 6.91 × 1010 m/kg, respectively. The pH of the sludge and filtrate changed slightly after PAC conditioning with fly ash coupling. These results indicate that fly-ash coupled with PAC and fly-ash coupled with PFS are expected to become a novel and effective environmental protection combined conditioning method for sludge dewatering.
Enhanced Microbial Oxidation–Neutralization Treatment of Acid Mine Drainage Rich in Ferrous Ions (Fe2+)
Authors: He Wenjie , Li Haibo , Xu Yin , Zhong Feng , Dong Hao , Wang Min
Published: May 2022

In this work, a method of enhanced packed-bed microbial oxidation–neutralization has been employed to treat Fe2+-rich acid mine drainage. The method features the use of a large number of immobile Acidithiobacillus ferrooxidans (A. ferrooxidans) in a bioreactor to promote the oxidation of Fe2+ to Fe3+. Results show that when the influent Fe2+ concentration is about 900 mg/L and the Fe2+ oxidation efficiency tends to 100%, the maximum oxidation rate of Fe2+ in the bio-ceramsite, bio-volcanic stone, and bio-activated carbon packed columns are 301 mg/(L·h), 234 mg/(L·h), and 139 mg/(L·h), respectively. Compared with the direct neutralization method, the enhanced microbial oxidation–neutralization method has several advantages. Firstly, it oxidizes Fe2+ to Fe3+, directly neutralizing the acid mine drainage at low pH and reducing the consumption of neutralizer. Secondly, more economical CaCO3 can be used as neutralizer. Thirdly, it produces precipitates with high solid content (5.50%), good settling performance (SV30 = 4%), and small volume, and the capillary suction time (CST) is 8.9 s, which is easy to dehydrate.
The Burden and Benefits of Knowledge: Ethical Considerations Surrounding Population-Based Newborn Genome Screening for Hearing
Authors: Mitchell Calli O. , Rivera-Cruz Greysha , Chau Matthew Hoi Kin , Dong Zirui , Choy Kwong Wai , Shen Jun , Amr Sami , Giersch Anne B. S. , Morton Cynthia C.
Published: May 2022

Recent advances in genomic sequencing technologies have expanded practitioners’ utilization of genetic information in a timely and efficient manner for an accurate diagnosis. With an ever-increasing resource of genomic data from progress in the interpretation of genome sequences, clinicians face decisions about how and when genomic information should be presented to families, and at what potential expense. Presently, there is limited knowledge or experience in establishing the value of implementing genome sequencing into newborn screening. Herein we provide insight into the complexities and the burden and benefits of knowledge resulting from genome sequencing of newborns.
Human Activity Recognition for Elderly People Using Machine and Deep Learning Approaches
Authors: Hayat Ahatsham , Morgado-Dias Fernando , Bhuyan Bikram , Tomar Ravi
Published: May 2022

There are more than 962 million people aged 60 and up globally. Physical activity declines as people get older, as does their capacity to undertake everyday tasks, effecting both physical and mental health. Many researchers use machine learning and deep learning methods to recognize human activities, but very few studies have been focused on human activity recognition of elderly people. This paper focuses on providing assistance to elderly people by monitoring their activities in different indoor and outdoor environments using gyroscope and accelerometer data collected from a smart phone. Smart phones have been routinely used to monitor the activities of persons with impairments; routine activities such as sitting, walking, going upstairs, going downstairs, standing, and lying are included in the dataset. Conventional Machine Learning and Deep Learning algorithms such as k-Nearest Neighbors, Random Forest, Support Vector Machine, Artificial Neural Network, and Long Short-Term Memory Network are used for human activity recognition. Long Short-Term Memory is a recurrent neural network variation that is best suited to handling temporal sequences. Two-fold and ten-fold cross-validation methods were performed to show the effect of changing the data in the training and testing dataset. Among all the classification techniques, the proposed Long Short-Term Memory Network gave the best accuracy of 95.04%. However, Support Vector Machine gave 89.07% accuracy with a very low computational time of 0.42 min using 10-fold cross-validation.
Research on Small Sample Data-Driven Inspection Technology of UAV for Transmission Line Insulator Defect Detection
Authors: Pan Lei , Chen Lan , Zhu Shengli , Tong Wenyan , Guo Like
Published: May 2022

Insulators are important safety devices on high-voltage transmission lines. An insulator inspection system based on UAVs is widely used. Insulator defect detection is performed against two main engineering problems: 1. The scarcity of defect images, which leads to a network overfitting problem. 2. The small object detection, which is caused by the long aerial photography distance, and the low resolution of the insulator defect area pictures. In this study, firstly, the super-resolution reconstruction method is used to augment the dataset, which can not only solve the overfitting problem but also enrich the image texture features and pixel values of defect areas. Secondly, in the process of insulator defect detection, a two-stage cascading method is used. In the first stage, the rotated object detection algorithm is used to realize the object location of insulator strings, and then images of the identified insulators are cropped to reduce the proportion of the background area in defect images. In the second stage, YOLO v5 is used for the detection of insulator caps that are missing defects. The method proposed shows good detection effect on the self-built training set which contains only 85 images captured from real inspection environments. The method has practical industrial application value.