bluuebunny/crossref_metadata_2025 huggingface dataset:
Pemahaman HAM dan Respon Mahasiswa Sekolah Tinggi Keagamaan Katolik terhadap Isu-isu Sensitif
Authors: Role Metoddyus Tri Brata , Simbolon Subandri
Published: October 2024

Artikel ini bertujuan untuk mengkaji pemahaman calon guru Agama Katolik terhadap implementasi Hak Asasi Manusia (HAM) dalam kaitannya dengan isu-isu HAM seperti gender, ideologi, dan keagamaan. Penilian ini dilakukan dengan menggunakan pendekatan kualitatif. Data dikumpulkan dengan menyebarkan angket terbuka kepada seluruh mahasiswa yang aktif dengan menggunakan bantuan google form. Dari hasil pengolahan data diketahui bahwa mahasiswa telah memiliki pemahaman tentang hak asasi manusia dan mengimplementasikan pemahaman tersebut dalam hubungannya dengan kelompok yang berbeda agama dengan sikap toleransi, menerima perbedaan dan menghargai. Namun terkait isu-isu sensitif seperti gender, partai atau organisasi politik terlarang, dan agama lokal, mereka masih mengandalkan pemahaman tekstual. Alasan utamanya adalah mereka jarang bertatap muka dengan orang-orang yang memiliki identitas gender, ideologi, dan agama lokal tersebut. Faktor lainnya adalah kurangnya pemahaman mereka mengenai pandangan inklusif Gereja mengenai isu-isu ini.
THE ROLE OF THE INDONESIAN NATIONAL ARMED FORCES (TNI) IN ADDRESSING TERRORISM AS AN EFFORT TO SAFEGUARD THE SOVEREIGNTY AND INTEGRITY OF THE UNITARY STATE OF THE REPUBLIC OF INDONESIA
Authors: Casmudin  , Sujono  , Sudarto
Published: October 2024

Acts of terrorism carried out systematically and massively create an atmosphere of widespread terror for citizens, effectively and efficiently, that the involvement of the TNI in eradicating criminal acts of terrorism, which is part of acts of terrorism, is not in the realm of law enforcement. Therefore, it is interesting to examine the position of the Indonesian National Army in the National Defense System of the Republic of Indonesia and the role of the Indonesian National Army in dealing with acts of terrorism as an effort to maintain the sovereignty and integrity of the Unitary State of the Republic of Indonesia. To answer these problems, normative legal research methods (normative juridical) are used with a statutory approach, case approach, conceptual approach, using secondary data obtained from primary, secondary and tertiary legal material sources. The research found that the position of the Indonesian National Army in the National Defense System of the Republic of Indonesia and the Role of the Indonesian National Army in Handling Acts of Terrorism as an Effort to Maintain Sovereignty is regulated in Article 30 Paragraph (5) of the 1945 Constitution of the Republic of Indonesia, apart from that in Paragraph (2) and Paragraph (3) This is confirmed in Article 3 and Article 4 of Law 34/2004 or the TNI Law, which states that in the deployment and use of military force, the TNI is subordinate to the President. Then the role of the Indonesian National Army in handling acts of terrorism as an effort to maintain the sovereignty and integrity of the Unitary State of the Republic of Indonesia as intended in Article 5 jo. Article 7 Paragraph (2) letter b number 3 which relates to the main tasks of the TNI in military operations other than war gives the TNI the authority to deal with acts of terrorism, based on state policies and political decisions. The position of the TNI in the state administration system is the main component of the state defense system to protect sovereignty, territorial integrity and the safety of the nation. To provide legal certainty and justice, it needs to be strictly regulated in ministerial regulations and/or Commander-in-Chief regulations regarding the role and duties of the TNI in dealing with acts of terrorism.
Toward a New Public Administration Model in Romania: The Challenges of Designing Coherent Public Administration Reforms
Authors: Profiroiu Constantin Marius , Hințea Călin Emilian
Published: October 2024

Reforming public administration in Romania has been a continuous challenge over the past decades, and the traditional model of public administration has been reshaped through various horizontal and vertical reforms. The problem is that these reforms have lacked coherent theoretical and practical trajectories. From the fall of the Communist regime in 1989 until Romania’s accession to the European Union, the new public management (NPM) paradigm predominantly influenced the public sector. Since 2007, no single model of reform has gained centrality, resulting in a mix of elements that have included NPM, the neo-Weberian state, and new public governance. This study explored and clarified the challenges that Romania has faced in designing reforms to enhance institutional efficiency and professional consistency.
Effect of Proprioceptive Neuromuscular Facilitation Technique on Pain, Range of Motion and Quality of Life in Adhesive Capsulitis - An Interventional Study
Authors: Soni Vaibhavi Prashantbhai , Shukla Yagna Unmesh
Published: October 2024

Background: Adhesive capsulitis is characterized by the development of dense adhesion, capsular thickening and capsular restriction. Proprioceptive Neuromuscular Facilitation (PNF) is an approach to therapeutic exercise that combines functional based diagonal patterns of movement with the technique of neuromuscular facilitation to evoke motor response and improve neuromuscular control and coordinated movements. Proprioceptive Neuromuscular Facilitation (PNF) aims to enhance mobility, movement control and joint coordination.
Method: After approval from the ethical committee, 34 patients were selected and randomly allocated into 2 groups, Group A (control) and Group B (Interventional). Group A (control) received conventional treatment while Group B (Interventional) received conventional plus PNF techniques (5 sessions) for 4 weeks. Pre and post interventional score of NPRS, Range of motion(goniometer) and SPADI scale were measured.
Results: After 4 weeks of intervention, Within Group analysis showed significant improvement on NPRS, range of motion(goniometer) and SPADI scale compared to pre data (p<0.05). In between-group analysis, Group B showed significant improvement on score of NPRS, range of motion (goniometer) and SPADI scale than Group A (p<0.05).
Conclusion: Group B showed statistically significant improvement on Pain, Range of motion and Quality of life compared to Group A.

Key words: Adhesive Capsulitis, Proprioceptive Neuromuscular Facilitation
Comparison of Rubberised Floor Vs Aquatic based Plyometric Training on Physical Fitness Variables of Collegiate Players
Authors: Jadiya Manoj Kumar , Rajpurohit Virendra Singh , Sharma Maliram
Published: October 2024

The purpose of this study was to compare the effects of 6-week plyometric training on two different surfaces, aquatic and rubberised floor on selected physical fitness variables namely; agility, cardiovascular endurance, explosive power, speed and muscle soreness in collegiate level players. These physical fitness variables are essential for athletes which can be enhanced by plyometric training. The plyometric training are exercises that are designed to enhance neuromuscular performance. Due to the powerful eccentric forces during the decelerating/landing phases, and rapid transition to the concentric propulsive phase, plyometric training can also constitute an effective training stimulus to reduce lower-extremity injuries in team sports. The plyometric exercises can be performed on different surfaces and each surface may prove different training stimulus as resistance of each surface is different.
Methodology: This comparative and experimental study included sample of 40 male collegiate players aged 18 to 25 years, which were randomly divided into two groups- aquatic training group (n=20) and rubberised floor training group (n=20). After the baseline measurements of variables plyometric training was given for 6-weeks, three sessions per week for both the groups.
Results: Data when compared after plyometric training revealed there was significant changes in performance of the players in both the groups (p≤0.05). Moreover, on comparing both the groups, aquatic group as well as rubberised floor showed more improvement in agility, CV and speed. While there were no significant changes seen in explosive power. The study also revealed that athletes showed less muscle soreness as compared to rubberised surface.
Conclusion: This study concluded that both the surfaces are able to enhance the performance of athlete. While comparing the groups aquatic surface plyometric training was found more effective than rubberised floor surface training in context with muscle soreness.

Key words: Plyometric Training, aquatic surface, rubberised floor surface, muscle soreness.
Nurses’ Knowledge and Practice on Medication Error in the Pediatric Hospital Setting - Narrative Review
Authors: E A Ebenezer. , R Francis Moses , Siby Reshmi
Published: October 2024

Aim: this study aimed to review the existing scientific articles regarding nurses’ knowledge, attitude and to practice on medication errors and to examine known pediatric medication administration errors.
Methods: A narrative review conducted by searching electronic databases: Pubmed, Embase and Scopus. The selection criteria were articles published between 2018-2022, English language, peer reviewed and any type of study design. Search terms were “Medication errors OR drug mistakes AND Pediatric care setting, paediatric wards NAD Nurse. The collected data were extracted and reviewed by 2 researchers independently. Characteristics of the articles were analysed by using frequency and percentage distribution.
Results: We retrieved a total of 10 studies, the majority published in 2018 and spanning eight countries. The majority of the studies were before and after intervention (80%). Three prospective cohort studies, four cross-sectional designs, and three survey studies were included. The intervention program enhanced the knowledge and practice among nurses in the pediatric care setting.
Conclusion: The study results indicate that implementing an appropriate intervention program using advanced technology can enhance nurses' knowledge, attitude, and practice in preventing medication errors in the pediatric care setting. We recommend conducting frequent continuing nursing education to update the protocol and dosage of newer medicines.

Key words: Medication error; nurses; pediatric hospital; prevention; knowledge; practice
A Systematic Review of the Integrated Disease Surveillance and Response Implementation Among African Countries Between 2010 and 2024
Authors: Muyembe Chisotwa , Kazong Eustarckio , Shitiavayi Songole Rogers
Published: October 2024

Background: The Integrated Disease Surveillance and Response (IDSR) approach, developed by the World Health Organization (WHO) and the African region, aims to enhance African countries' capacity to identify and address public health threats. This approach is crucial in mitigating the prevalence of emerging and re-emerging infectious diseases in Africa, where health systems often face significant challenges. However, the implementation of IDSR systems varies across the continent. The object of the review was to evaluate the performance of IDSR systems in Africa by examining their core and supportive functions and surveillance attributes. The objective of the review is to identify strengths and weaknesses in IDSR implementation, assess the effectiveness of these systems in detecting and responding to public health threats, and provide recommendations for improvement.
Methods: Following PRISMA guidelines and the PICOS framework, an extensive search of scholarly databases identified 61 relevant publications from 2010 to 2024. These studies were evaluated using the AACODS (authority, accuracy, coverage, date, and significance) checklist the STROBE critical review checklist, and the Joanna Briggs Institute checklist. Furthermore, key metrics were used such as data reporting, outbreak detection, and response timeframes, considering contextual factors affecting IDSR success in different countries.
Results: The review reveals significant variability in IDSR performance across African countries. Some countries have effectively implemented IDSR, demonstrating strong data reporting, timely outbreak detection, and rapid response capabilities. Others face challenges such as inadequate infrastructure, insufficient training, and poor data management, limiting their IDSR effectiveness. Supportive functions like supervision, feedback, and resource availability are critical in enhancing IDSR performance.
Conclusion: Strengthening IDSR systems in Africa is crucial for better detecting and responding to public health threats. Despite progress, significant gaps remain, particularly in countries with less developed health systems. Targeted actions, including increased budget allocation, infrastructure development, and capacity building, are needed to address these gaps.

Key words: Infectious; Implementation; International Health Regulations; challenges; opportunities
Exploring the Impact of Diet on Inflammation in Neurological Disorders: A Review
Authors: Rapelly Sushma Swaraj , Suri Shalini , Saif Afreen
Published: October 2024

Introduction: Neurological disorders pose significant challenges globally in terms of disability and mortality. Increasing evidence underscores the role of inflammatory processes and gut microbiome imbalances in these conditions, prompting exploration into dietary approaches like the Mediterranean, ketogenic diets, and DASH (Dietary Approaches to Stop Hypertension) for their potential benefits. With ongoing advancements in understanding neurodegenerative diseases like Alzheimer’s, Parkinson’s, Multiple sclerosis, Depression, and Schizophrenia, there is a heightened focus on finding more impactful interventions.
Methods: This review delves into the influence of diet and its components on inflammation linked to neurological diseases like Alzheimer’s disease development and progression. Data from in vitro experiments, animal models, and various studies are integrated, providing a comprehensive analysis of effectiveness of nutritional interventions to combat neurodegenerative disorders. Systematic searches of reputable databases like PubMed and Google Scholar ensured the inclusion of up-to-date and reliable literature.
Key Findings: Data suggests that adopting a diet rich in anti-inflammatory elements such as minerals, vitamins, polyphenols, omega-3 fatty acids and probiotics from vegetables, fruits, spices, herbs, nuts, and legumes could foster a brain-friendly environment and reduce neurological disease risks.
Conclusion: Nutritional strategies hold promises as a non-invasive and effective approach to combatting these disorders.

Key words: Neurological conditions, inflammation, anti-inflammatory diet, Nutrition intervention, psychological disorders, Degenerative brain disorders, Alzheim
Pharmacogenomics in the Age of Personal Genomics: A Concise Guide to Online Resources and Tools
Authors: Karri Srinivasa Reddy , Dangeti Vinay Kumar , Manda Latha Mangeswari
Published: October 2024

The post-HapMap era has witnessed a significant expansion in resources available for genome analysis and interpretation, alongside the development of numerous databases and consortia dedicated to personal genomics. The emergence of next-generation sequencing technologies has accelerated the growth of personal genomics, while also indirectly advancing the field of pharmacogenomics (PGx). Modern pharmacogenomics has progressed beyond merely identifying variations in common genes related to frequently used drugs, evolving into a comprehensive study of the interactions between single genes and multiple drugs, as well as the effects of combinatorial drug use. The vast increase in genomic data has prompted the growth of specialized databases and consortia focused on PGx and the curation of this data. This review provides an overview of key online resources and tools essential for interpreting personal genomes, with a focus on pharmacogenetically relevant data. The resources are categorized into five main sections according to their content and utility, encompassing pharmacogenomics databases, variation databases, tools and resources for analyzing pharmacogenomic data, community efforts and consortia, as well as standards for data representation.

Key words: Pharmacogenomics, Single-nucleotide variations, Data Bases, Datasets
Transforming Primary Health Care in Delhi:
A Policy Review of the Mohalla Clinic Model
Authors: Ahmed Ishtiyaque
Published: October 2024

Initiated by the Delhi government in 2015, Mohalla Clinics aim to deliver essential primary healthcare services within local neighbourhoods, particularly in underserved and remote areas with limited access to public health facilities. This study reviews the impact of Mohalla Clinics on strengthening primary healthcare and advancing universal health coverage (UHC) in Delhi. It highlights the clinics' role in addressing urban healthcare disparities, improving primary care access, and reducing out-of-pocket expenditure (OOPE). Demographic analysis shows that a significant proportion of clinic users are women, the elderly, and low-income individuals with primary-level education. High satisfaction rates are reported for service quality, doctor-patient interactions, and the likelihood of repeat visits. The majority of patients benefit from free consultations, medications, and diagnostic tests, reflecting the clinics’ emphasis on affordability and accessibility. The study advocates for integration with existing public health initiatives, such as Urban Primary Health Centers (U-PHCs) under the National Urban Health Mission (NUHM), to further enhance healthcare delivery. Mohalla Clinics are especially beneficial to pregnant and breastfeeding women, positioning them as key players in advancing health reforms and achieving UHC. The findings underscore the need for sustained political support to expand these clinics and strengthen their role in delivering accessible and affordable healthcare to underserved populations in Delhi, significantly contributing to UHC goals in India.

Key words: Primary health care, Mohalla clinic, Universal health coverage, Accessibility, Affordable health care, Quality health services.
Rare Case of Scar Ectopic Pregnancy with No Cardiac Activity
Authors: Karne Jahanavi
Published: October 2024

This report is about case of CSP diagnosed at Government General Hospital Nizamabad. A woman of age 32 yrs with obstetric formula G3P2L2 with previous two cesarean section with 6 weeks and 2 days of amenorrhea and UPT positive came with complaints of bleeding per vagina and abdominal pain. On trans abdominal sonography CSP was confirmed. There was no cardiac activity seen and uterus was found to be retroverted. Initially serum HcG levels were <10,000mIU/ ml therefore it was managed medically using systemic Methotrexate followed by uterine evacuation and products of conception were sent to histopathological examination.

Key words: cesarean scar pregnancy, no cardiac activity, 3rd gravida, retroverted uterus
Self-Efficacy: A Major Contributor to Improved Quality of Life in a Patient Undergoing Complete Decongestive Therapy for Filarial Lymphedema: A Case Study
Authors: N Athole Yuvraj , V Shetye Jaimala
Published: October 2024

Filarial lymphoedema is a tropical parasitic worm illness caused mostly by Wuchereria bancrofti. It poses a significant burden in India, accounting to 39% of the global cases. We present a case of a 32-year-old male with lymphatic filariasis for 9 years. Massive disfiguring lymphedema of his lower leg caused difficulty in ambulation and reduced social participation. The patient received complete decongestive therapy (CDT) in an outpatient setting. Interventions included manual lymphatic drainage, multi-layered compression bandaging, aerobic exercise, electrical stimulation, and exercises with elevation to reduce the excess volume of the limb. A 19-day physical therapy program over 14 weeks led to significant improvement in reducing limb volume, enhancing limb shape, increasing functional capacity, and improving the overall quality of life even emphasizing the impact of self-management after discharge.

Key words: Complete decongestive therapy (CDT), LF-Specific Quality of Life Questionnaire (LFSQQ), Dermatology life quality index (DLQI), Manual lymphatic drainage (MLD), Multi-layer lymphatic bandaging (MLLB), Home exercise program (HEP).
Effectiveness of Azadirachta indica and Ocimum gratissimum for Acne Vulgaris: A Literature Review
Authors: Wijaya Natalia , Sriyani Gusti Agung Ayu
Published: October 2024

Acne vulgaris is a common dermatological condition characterized by inflammation of the pilosebaceous units, predominantly affecting adolescents and young adults. Its multifactorial etiology involves hormonal imbalances, microbial overgrowth, and environmental factors, leading to increased sebum production and inflammation. Conventional treatments often vary in efficacy and tolerability, driving interest in alternative therapies to reduce the severity and recurrence of lesions and enhance appearance, the acne severity. This literature review explores the therapeutic potential of two herbal remedies, Azadirachta indica (Neem) and Ocimum gratissimum (African basil), known for their antimicrobial, anti-inflammatory, and antioxidant properties. Azadirachta indica is recognized for its rich phytochemical profile, including compounds like nimbin and azadirachtin, which effectively combat acne pathogens such as Cutibacterium acnes. Meanwhile, Ocimum gratissimum exhibits significant antimicrobial and antioxidant activities, contributing to skin healing and sebum regulation. The combined use of these herbs offers a holistic approach to acne management, targeting multiple aspects of its pathogenesis, including inflammation and microbial imbalance. The therapeutic benefits of Azadirachta indica and Ocimum gratissimum highlight their valuable role in advancing dermatological care and offer promising prospects for individuals seeking holistic and plant-based solutions for acne management. This review emphasizes the potential and effectiveness of Azadirachta indica and Ocimum gratissimum in advancing dermatological care and providing effective, plant-based solutions for acne management.

Keywords: Acne vulgaris, azadirachta indica, clove basil, neem, ocimum gratissimum, treatment
Prevalence of Urolithiasis in Diabetes Mellitus Patients
Authors: Tanggo Christian Ronald
Published: October 2024

Background: Urolithiasis and Diabetic Mellitus are common pathologies in the general population, and the lifetime risk of urolithiasis is 12-15% for a man and 5-15% for a woman with up to 50% of the lifetime recurrence ratio. Recent results of urolithiasis prevalence among the diabetic population are varied from 7-21%. We evaluated the prevalence of urolithiasis in the diabetic population in Hasan Sadikin General Hospital, Bandung.
Material and Methods: We performed ultrasound and IVP in diabetic people who have a history of colic or other urinary stone symptoms. The presence of urinary calculi was recorded.
Result: From June 2011 to July 2012, 139 diabetic subjects were participated. Mean age was 49,73 years (CI95= 47,79-51,67), and 78,57% were males. We found 14 cases of urolithiasis in diabetes mellitus subjects (10,07%), and 78,57% of them were males. The 4th-decade group diagnosed urolithiasis was 6 subjects (42,86%), which was the largest case found in the diabetic population.
Conclusions: The prevalence of urolithiasis in the diabetic population in Hasan Sadikin GH was 10.07% in 2012.

Keywords: urolithiasis, diabetic mellitus
Risk Factors for Gastric Cancer at RSUP Prof. Dr. I.G.N.G. Ngoerah Year 2018-2023
Authors: Saraswati Muthia , SpB-KBD(K) Made Agus Dwianthara Sueta, , SpB-KBD I Made Mahayasa,
Published: October 2024

Gastric cancer is the fifth most common cancer and the fourth most common cause of death due to cancer in the world. The development of gastric cancer tends to be quite slow and takes years, so it is often found in the late stages. The cause of stomach cancer is not known for certain, but it is believed to be caused by many factors. This study aims to determine the risk factors for gastric cancer at RSUP Prof. Dr. I.G.N.G. Ngoerah was diagnosed in 2018-2023. This research was conducted using a retrospective descriptive method using secondary data in the form of medical records on 46 samples of gastric cancer patients who were controls or treated at RSUP Prof. Dr. I.G.N.G. Ngoerah was diagnosed in 2018-2023 The variables studied include the dependent variables, namely age, gender, peptic ulcers, blood type, obesity, alcohol consumption and smoking. The results of the analysis showed that gastric cancer patients at RSUP Prof. Dr. I.G.N.G. The majority are over 50 years old (82.6%), male (58.7%), have no peptic ulcers (89.1%), have blood type A (37%), underweight (50%), are not consume alcohol (97.8%), and do not smoke (97.8%).It can be concluded that the risk factors for gastric cancer patients at RSUP Prof. Dr. I.G.N.G. Ngoerah majority are over 50 years old, male, have no peptic ulcers, have blood type A, are underweight, do not consume alcohol and do not smoke.

Keywords: Gastric Cancer, Risk Factors, RSUP Prof. Dr. I.G.N.G. Ngoerah
Musculoskeletal Health Problems Among the Loom Weavers of Sirajganj District, Bangladesh
Authors: Prasetiawan Adi , Banowati Eva , Hardati Puji
Published: October 2024

Land use change is increasing in West Nusa Tenggara province, especially in Bima district. This condition occurs because people who make land use change patterns that are utilized as agricultural areas for corn commodities. The limited agricultural land in Bima Regency with the potential for good selling prices of corn commodities is a major factor in land use change, this has an impact on flood disaster vulnerability. This study aimed to determine the condition of the livelihood assets of seasonal corn farmers in the Bima district. The research method used a descriptive presentative statistical approach. The sample in this study amounted to 97 respondents who were taken in 8 districts with flood vulnerability, namely Sanggar, Madapangga, Palibelo, Woha, Belo, Monta, Sape, and Lambu. Random sampling was used to determine the respondents. The results showed that the condition of the livelihood assets of seasonal corn farmers in Bima District from 8 flood-prone villages is dominated by human resources, where the average percentage value is 83%. This is followed by physical assets at 81% and natural and financial resources at 71%, while the lowest is social assets with a percentage value of 69%. The farmer livelihood assets with high percentage values in each flood-prone area are human resources in Sanggar, natural resources in Palibelo, financial and physical in Sape, and social assets in Palibelo and Woha. The pentagon of livelihood assets does not form a triangle, so it can be concluded that there is inequality between assets. The lack of agricultural land owned by farmers encourages the use of land cover as corn farmland. This can be seen from the use of land by farmers that is not their own, resulting in environmental damage that causes flood vulnerability.

Keywords: Land use change, Livelihood assets, Flood Disaster
Musculoskeletal Health Problems Among the Loom Weavers of Sirajganj District, Bangladesh
Authors: Sanyal Ankan , Happy Taslima Akber , Ghosh Bishal
Published: October 2024

Loom industry in Bangladesh is the foremost imperative & antiquated house industry with a decentralized setup. The industry is giving vocation for millions of individuals within the nation. The target populace includes weavers over northern Bangladesh. The ponder secured a sizable number of population i.e, 208 subjects in Enayetpur and Madhabpur village, Sirajganj. To ensure representativeness, a non-probability convenience technique was utilized to choose a test estimate of 208 members. To be qualified for the study, members were chosen who had minimum two years of experience. Male were predominant (96.2%) among the respondents. Monthly income showed that major part (48.1%) of the respondents fell in 10-15thousand BDT category. Majority (63.5%) of waste disposal strategy taken after by the wok-places was landfilled. What's really interesting is that many respondents reported having musculoskeletal problems; lower back pain (59.6%) was the most frequently reported one. These health issues were connected to weaving activities because they involve lots of repetitive movements with hands, shoulders, legs, and other parts. Most health concerns in this field came from ergonomic risk factors. Future research should aim to include diverse populations and explore interventions that can mitigate these ergonomic risks, ultimately improving the well-being of this vital workforce in Bangladesh's loom industry.

Keywords: Bangladesh, Sirajganj, musculoskeletal, health, loom, weavers
Study of the Influence of the Variability of Traffic-Related Parameters on the Service Life of Flexible Pavement Structures in Senegal by a Mechanistic-Empirical Approach
Authors: Diouf Babacar , Ba Makhaly , Coulibaly Mory
Published: October 2024

The results of the study showed that exceeding the axle load and axle configuration are indisputably among the most damaging factors for flexible pavement structures in Senegal, made of local materials (Diack basalt, Sindia laterite). The regulatory axle load recommended by UEMOA for users is set at 11.5 tons and 12 tons for a single and twin axle respectively. For calculation purposes, this load is set at 13 tons. However, in Senegal, this axle load is often exceeded, and given the diversity of heavy goods vehicles in traffic, single axles, whose effects, according to several authors, are more detrimental to flexible pavement structures, are increasingly observed in road traffic. Differences in fatigue cracking and rutting damage between single and dual wheels, as well as load overruns, show the need to take axle configuration and possible overloads into account when dimensioning flexible pavement structures in Senegal, and when planning their maintenance, the costs of which are excessively high, according to Senegal's Autonomous Road Maintenance Fund (FERA).

Keywords: Single wheel, dual wheel, damage, fatigue cracking, rutting, traffic
Homeostatic Effect of Phoenix Dactylifera on Alloxan-Induced Diabetes and Aluminium-Induced Neurotoxicity in Male Wistar Rats
Authors: Ogadinma Ilochi Nwabunwanne , Olof Ushie Cecilia , Chuemere Arthur Nwafor
Published: October 2024

Introduction: This study assessed homeostatic effect of Phoenix dactylifera on alloxan-induced diabetes and aluminium-induced neurotoxicity in male wistar rats divided into 5 groups of 5 rats each.
Methods: Group A; control, Group B; diabetic group, Group C; AlCl3, Group D Alloxan+ P. dactylifera, Group E; AlCl3 + P. dactylifera (0.5ml each). Diabetes was experimentally induced in groups B-D. The animals were left to acclimatize for 2 weeks and treatments were dissolved in distilled water and given orally for 2 weeks (4weeks). Blood sample was collected via ocular puncture for analysis of fasting blood glucose level. At the end of 4 weeks, the animals were sacrificed and blood samples taken for estimation of oxidative stress markers. Blood and brain samples were collected for neuromuscular function markers.
Results: The results were statistically significant at 95% confidence interval. The results obtained when compared to control from showed group D and E exhibited decrease levels of lipid peroxidation (MDA), increased levels of antioxidant enzymes (SOD, CAT, GPx and GSH). There was also decrease BGL2, indicating positive glycemic control. When compared to the diabetic group, the treatment group showed a significant reduction in MDA levels and significant increase in the levels of GSH, CAT, SOD, and GPX. It also showed significant decrease in CKMM levels (less muscle activity and damage), and increase in AChE indicating nerve activity and stress was observed in control group too. Significant reduction in FBGL2 were shown. There was no significant difference in FBG1 levels.
Conclusion: P. dactylifera aqueous extract exhibits potential antidiabetic and antioxidant effect in Alloxan-induced diabetic and aluminium-induced toxicity in male wistar rats.

Keywords: Phoenix dactylifera; Neurologic; Diabetes; Phytochemical; Therapy
A Quiziz Game-Based Learning Implementation in Improving Learner’s Critical Thinking Skills
Authors: Mahmudah Mellania Nur , Setyowati Dewi Liesnoor , Pramono Suwito Eko
Published: October 2024

This study aims to determine the effectiveness of game-based learning through Quizizz in improving the learning outcomes of seventh-grade social studies students at SMP Negeri 7 Semarang. The research employed a pre-experimental design, specifically the one-group pre-test-post-test method. Data sources included teachers, students, the learning process, relevant documents, and validators. Data were collected through observations, document analysis, and questionnaires. The data analysis utilized the N-Gain test and the T-Test, with the predetermined minimum completeness criteria. The findings demonstrate that game-based learning through Quizizz is highly feasible and effective.
The validation data indicate that Quizizz as a tool for improving critical thinking skills has a high level of validity, with average scores of 95.7% from media experts, 100% from material experts, and 100% from experts in critical thinking. The N-Gain analysis indicated a 29% improvement in the first cycle, categorized as Less Effective, and an 82% improvement in the second cycle, categorized as Quite Effective. In addition, the significance value of 0.00 indicates a statistically significant difference between the two groups.

Keywords: Game-Based Learning, Quizizz, Critical thinking
Navigating the AI/ML-Driven Future of HRM: Balancing Technological Innovation with Human Collaboration
Authors: Basnet Sunil
Published: October 2024

In the age of rapid technological advancement, the integration of Artificial Intelligence (AI) and Machine Learning (ML) into Human Resource Management (HRM) practices is reshaping the landscape of modern workplaces. This article explores the multifaceted dynamics of this integration, exploring how AI/ML technologies are revolutionizing HRM while emphasizing the critical importance of human collaboration in this evolving paradigm. Through an in-depth analysis of current trends, challenges, and opportunities, this paper elucidates the myriad benefits that AI/ML offer to HRM, ranging from enhanced decision-making to streamlined processes. However, it also underscores the indispensable role of human expertise, empathy, and ethical considerations in harnessing the full potential of AI/ML in HRM. Drawing upon a rich body of existing literature and insightful case studies, this article provides nuanced insights into the future trajectory of HRM, advocating for a balanced approach where AI/ML seamlessly integrates with human capabilities to foster a collaborative environment. Ultimately, this exploration serves as a guiding beacon for organizations navigating the AI/ML-driven future of HRM, emphasizing the imperative of aligning technological innovation with human-centric values to achieve organizational success and employee well-being in the digital age.

Keywords: AI, ML, Human Resource Management, Collaboration, Technology, Future of Work
Peningkatan Kapasitas Kader Perempuan melalui Pendidikan Politik Berbasis GEDSI
Authors: Malihah Elly , Nurbayani Siti , Komariah Siti , Utami Lingga , Munggaran Rengga Akbar , Rizkia Arindini Ayu Kisvi , Yusup Andreian , Fadhillah Faiq Akmal , Pratama Rexa Putra
Published: October 2024

Penelitian ini bertujuan menganalisis implementasi pelaksanaan program pendidikan politik berbasis Gender Equality, Disability, and Social Inclusion (GEDSI) yang dilaksanakan di Kecamatan Antapani, Kota Bandung, Provinsi Jawa Barat. Pendekatan penelitian yang digunakan adalah kualitatif dengan metode deskriptif. Teknik pengumpulan data yang digunakan adalah wawancara mendalam, observasi partisipatif, dan studi literatur. Temuan penelitian menunjukkan pendidikan politik berbasis GEDSI bagi kader penggerak perempuan ini adalah memberikan pemahaman mendalam pengetahuan dan keterampilan yang memfasilitasi partisipasi mereka dalam proses advokasi politik. Melalui strategi yang bersifat partisipatif dan bottom-up, pendidikan politik berbasis GEDSI memberikan kader perempuan alat yang efektif untuk memperkuat kapabilitas mereka. Sebagai hasilnya, kader perempuan yang teredukasi secara holistik diharapkan dapat berperan aktif dalam menciptakan tatanan politik yang lebih inklusif, demokratis, dan berkeadilan.
Association of physical activity and risk of cardiac disease among adults
Authors:   Faculty of Rehabilitation & Allied Health Sciences, Riphah International University Islamabad Pakistan, Bano Malaika , Omar Mian ,   Pakistan Atomic Energy Commission Islamabad Pakistan, Ali Shah Afaq ,   City University of Science and Information Technology, Peshawar Khyber Pakhtunkhwa, Pakistan, Iqbal Saqib ,   City University of Science and Information Technology, Peshawar Khyber Pakhtunkhwa, Pakistan, Bano Muqadsa ,   University of Peshawar, Peshawar, Khyber Pakhtunkhwa, Pakistan
Published: October 2024

Background: Nowadays the level of physical activity is compromised among all, especially in young adults, which may contribute to early development risk of cardiac disease. Objective: To determine the association of risk of cardiac disease with physical activity among young adults. Methods: A cross-sectional study was conducted from January 2024 to April 2024 at Iqra National University, Peshawar after approval from the ethical committee. A total of n=102 undergraduate male and female students between the age of 18-24 years were included in the study. To determine the physical activity of the participants International Physical Activity Questionnaire - Short Form was used. To evaluate the risk of cardiac disease was observed according to the National Cholesterol Education Program. Results: The mean age and BMI of the n=102 study participants were 23.22±3.4 years and 23.37±5kg/m2 respectively. The risk of cardiac disease was found in n=45(44.1%) while most of the participants (n=33) were moderately and (n=42) highly physically active with a mean METs score of 2881.51±2704.83. Physical activity (PA) is not significantly associated (p=0.44) with the risk of cardiac disease. However, gender showed a strong association (p<0.001) with the risk of cardiac disease among the participants. A total of n=24(88.8%) females had the risk, out of n=27, while n=21(28%) males had the risk of cardiac disease out of n=75 males. Conclusion: The study concluded that physical activity had a non-significant relation with the risk of cardiac disease while in the case of gender females are more prone to have the risk of cardiac disease. Keywords: Cardiac diseases, physical activity, risk factors
Enhanced methyl green adsorption of ZIF-8 metal-organic framework: Insights from different solvents
Authors: Zahedi Asl Saeid , Hooriabad Saboor Fahimeh
Published: October 2024

This study investigates the effect of solvent type on the structural properties and adsorption performance of the ZIF-8 metal-organic framework for removing various dyes including, methyl green (MG), methylene blue (MB), and methyl orange (MO) from water in acidic and alkaline environments. ZIF-8 samples were synthesized using zinc nitrate, methylimidazole, and three different solvents including, water, methanol, and ethanol under atmospheric pressure and 70 °C. Characterization using BET, XRD, FT-IR, and TGA techniques sheds light on the structural, chemical, and thermal properties of ZIF-8 samples. Among the samples, ZIF-8/M, synthesized using methanol, stands out, demonstrating the high surface area of 2172.7 m2/g, large total pore volume of 1.5412 cm3/g, and high crystallinity of 31.9% with improved thermal stability. Furthermore, ZIF-8/M shows better adsorption performance for methyl green with a removal percentage of 81.9%, 87.1%, and an adsorption capacity of 20.5 mg/g and 21.8 mg/g, in acidic and alkaline environments, respectively. Enhanced dye adsorption of ZIF-8/M is associated with both physical and effective chemical adsorption mechanisms via tuning the environment's acidity.
DOENÇA DE ALZHEIMER (DA): DEFICIÊNCIA DE VITAMINA B12 ESTÁ ASSOCIADA A ESCORES MENORES NO MINIEXAME DO ESTADO MENTAL (MEEM)
Authors: Komatsu C , Komatsu RS
Published: October 2024

Objetivo: Doença de Alzheimer (DA) é a principal causa de demência em idosos, e várias linhas de evidência indicam que a hipovitaminose B12 está associada a ela. Os processos bioquímicos envolvidos na DA, que são afetados pela vitamina B12, são: processamento APP, fibrilação Aβ, dano oxidativo induzido por Aβ, hiperfosforilação tau e agregação tau. Método: Cento e três pacientes ambulatoriais com o diagnóstico de DA, de acordo com critérios propostos por NINCDS-ADRDA (2011), acompanhados em um hospital universitário público, tiveram seus níveis de vitamina B12 acessados e escores no MEEM avaliados. Conclusão: Noventa e um pacientes (88,35%) apresentaram níveis normais de vitamina B12 (200-800 pg/ ml) e 12 (11,65%), deficiência de vitamina B12 (≤ 200 pg/ml). Do grupo com níveis normais, 13 pacientes (14,29%) apresentaram comprometimento cognitivo grave (MEEM < 10), 33 (36,26%), comprometimento cognitivo moderado (MEEM = 10-20) e 45 (49,45%), comprometimento cognitivo leve (MEEM > 20). Do grupo com deficiência, dois pacientes (16,8%) apresentaram comprometimento cognitivo grave; cinco (41,6%), comprometimento cognitivo moderado; e cinco (41,6%), comprometimento cognitivo leve. Ambos os grupos, com níveis normais de vitamina B12 e com deficiência, tinham, em média, a mesma escolaridade: 2,91 e 3,42 anos, respectivamente. Conclui-se, portanto, que, nesta amostra de pacientes com DA, hipovitaminose B12 está associada a menores escores no MEEM quando comparada com níveis normais de vitamina B12.
AVALIAÇÃO DE DESEMPENHO DA GLICOSE EM DIFERENTES EQUIPAMENTOS DE GASOMETRIA UTILIZADOS PELOS LABORATÓRIOS PARTICIPANTES DE UM PROGRAMA DE AVALIAÇÃO EXTERNA DA QUALIDADE
Authors: Poloni JAT , Corrêa MA , Vieira AO , Jerônimo DJS , Dias CMM , Vasconcellos LS , Montes JVR , Bastos CR
Published: October 2024

Objetivo: O controle efetivo dos níveis de glicemia depende tanto de dados precisos quanto da disponibilidade dos resultados em tempo hábil para tomada de decisão clínica. A gasometria é um exame empregado para diagnóstico, controle e monitoramento do tratamento de pacientes críticos, e os gasômetros geralmente contemplam, no portfólio, dosagem de glicose, principalmente pela praticidade e rapidez. Este estudo teve como objetivo principal avaliar o desempenho da glicose dosada em diferentes equipamentos de gasometria dos participantes de um ensaio de proficiência (EP). Método: O EP foi realizado com quatro rodadas/ano (três amostras de solução sintética gaseificada/rodada, em diversas concentrações) no período de março de 2010 a março de 2023. Neste mesmo período, foi avaliada a evolução do coeficiente de variação (CV) médio e verificado o percentual de adequação (%A) dos participantes. Conclusão: Foram analisados 28.140 dados. Os principais equipamentos utilizados pelos participantes foram Gem Premier 3500 (n = 297), Rapidpoint Séries (n = 110), Gem Premier 3000 (n = 107) e ABL Séries 800 (n = 92). Houve aumento no número de laboratórios participantes de 27 (2010) para 335 (2023). O %A variou de 73% em 2010 para 92% em 2023, com tendência de melhora (p < 0,05). Entre 2010 e 2023, os CVs apresentaram diminuição significativa (p < 0,05) com o tempo, variando entre 1,5% e 4%. O estudo revelou desempenho geral satisfatório dos participantes para a análise de glicose em equipamentos de gasometria, além da importância da participação contínua em EPs para a melhoria dos resultados. A compreensão e a correção da inexatidão (erro sistemático) do processo analítico são essenciais para atingir a qualidade e a confiabilidade desejadas dos resultados na rotina laboratorial. Referência: 1. Liang Y, Wanderer J, Nichols JH, Klonoff D, Rice MJ. Blood gas analyzer accuracy of glucose measurements. Mayo Clin Proc. 2017 Jul; 92(7): 1030-1041. doi: 10.1016/j.mayocp.2017.03.009. Epub 2017 Jun 20. PMID: 28645518.
PRÉ-ECLÂMPSIA E RISCOS LATENTES APÓS O PARTO – ESTUDO PERLA: AVALIAÇÃO DE DÍMERO D E PAI-1
Authors: Silva TEM , Silva LG , Costa IM , Ferreira APS , Dusse LMS , Novais JSM , Alpoim PN
Published: October 2024

Objetivo: As doenças cardiovasculares (DCV) são a principal causa de morte no mundo. O dímero D (Di-D) e o inibidor do ativador do plasminogênio (PAI-1) são biomarcadores associados a doenças que cursam com hipercoagulabilidade, como infarto agudo do miocárdio, acidente vascular encefálico e trombose venosa profunda. A presença de hipertensão, o aumento do índice de massa corporal (IMC) e o histórico de pré-eclâmpsia (PE) são fatores de risco para DCV em mulheres. PAI-1 e Di-D já foram correlacionados com a PE, mas pouco se sabe sobre sua participação nos efeitos tardios da PE e sua possível aplicação na avaliação do risco cardiovascular (CV). Método: Neste estudo, foram avaliados características físicas e níveis séricos de PAI-1 (Elisa) e Di-D (imunoturbidimetria) em 38 mulheres que tiveram gestações de risco habitual e em 40 com histórico de PE entre os anos de 2008 e 2016. Conclusão: As mulheres com histórico de PE apresentaram maior peso (p = 0,02), IMC (p < 0,01), percentual de gordura (p = 0,02), pressão arterial sistólica (p = 0,02), pressão arterial diastólica (p < 0,01), circunferência de cintura (p = 0,01), abdômen (p < 0,01) e quadril (p = 0,02). Os níveis de PAI-1 [59,32 (47,14) vs. 40,95 (40,17) ng/ml; p = 0,13) e Di-D [241 (209) vs. 236 (183) ng/ml; p = 0,83] foram semelhantes entre mulheres com e sem histórico de PE, respectivamente. Acredita-se que a PE e as DCV compartilham uma predisposição a doenças vasculares e metabólicas. O histórico de PE associado a alterações endoteliais, ao aumento da pressão arterial e à alteração da composição corporal pode favorecer o surgimento de DCV. A tendência ao aumento do risco de DCV em mulheres com histórico de PE mostra a necessidade do acompanhamento delas ao longo de suas vidas para reduzir o impacto do antecedente de PE sobre o risco CV. PAI-1 e Di-D são biomarcadores de fase aguda que se alteram em doenças que cursam com intensa hipercoagulabilidade. Por isso, supõe-se que os níveis desses marcadores estão alterados apenas no momento do evento CV.
PERFIL GLICÊMICO DE IDOSOS DE UM LABORATÓRIO DE ANÁLISES CLÍNICAS EM BOA VISTA, RORAIMA
Authors: Dias MP , Moura IO , Felix Júnior HWO , Barreto BO , Araújo CM , Nery LFA
Published: October 2024

Objetivo: Traçar o perfil glicêmico de pacientes idosos atendidos em um laboratório de análises clínicas localizado em Boa Vista, Roraima, levando em consideração poucos estudos nessa região. Método: Trata-se de um estudo transversal, retrospectivo e de base populacional, o qual avaliou os resultados de glicemia de pacientes durante o ano de 2022. Foram analisados resultados de 2.312 pacientes com faixa etária de 60 a 90 anos, de ambos os sexos, respeitando-se o jejum mínimo de 8 horas. Os resultados foram obtidos de um banco de dados sem identificação individual, com dispensa de tramitação no sistema CEP/CONEP. Conclusão: Do total de pacientes, 1461 eram do sexo feminino (63,1%) e 851, do masculino (36,8%). A análise do perfil glicêmico foi dividida segundo os valores de referência utilizados pelo laboratório – para pacientes do sexo feminino: < 69 mg/dl de 0,40%; 70 a 99 mg/dl de 32,10%; 100 a 125 mg/dl de 21,4%; > 126 mg/dl de 9,3%; para pacientes do sexo masculino: 70 a 99 mg/dl de 13,8%; 100 a 125 mg/dl de 15,2%; > 126 mg/dl de 7,8%. Os resultados evidenciaram que 53,7% dos pacientes obtiveram valores de glicemia acima de 100 mg/dl, os quais podem caracterizar uma intolerância a glicose ou diabetes. Sabendo-se que o envelhecimento é um dos fatores de predisposição dessa patologia, o monitoramento laboratorial é indispensável para prevenir possíveis complicações e acompanhar o tratamento.