bluuebunny/crossref_metadata_2025 huggingface dataset:
Ariel Godoy Astica y el nacimiento del cuento homosexual en Chile
Authors: Cisternas Cruz Cristian
Published: July 2023

Este artículo refiere al nacimiento del cuento homosexual en Chile y presenta como hallazgo investigativo el cuento “Algo extraño” (20 de diciembre, 1959) del narrador chileno Ariel Godoy Astica. Junto a “La mala ventura de Nanito Velásquez” (1959) de Edesio Alvarado, este relato puede ser considerado como el primero, en la forma de cuento, dentro de las letras chilenas, en donde se muestra abiertamente una vinculación con la cultura homosexual. Con respecto a la fábula, la narración de Godoy Astica nos presenta a su protagonista Camilo, un joven de diecisiete años de edad, quien siente “algo extraño” por Dalzare, otro niño de trece años; lo extraño es la pasión amorosa. El cuento, cuya temática central es este enamoramiento, presenta esta forma de amor homosexual de manera romántica, pura y platónica. Para articular su universo narrativo, este relato, como en algunos de los momentos anteriores de la literatura chilena (poesía y novela), recurre a la sublimación para dar a conocer las vivencias relacionales del vivir homosexual, escapando a lo escabroso de un entorno social degradado y degradante. Se reafirma con este cuento de Godoy Astica a la literatura homosexual como testimonio y expresión de lo subalterno, lo sublime, aunque sin tocar la fantasía (Sutherland 2001).
crónica como memoria del conflicto armado colombiano. Los escogidos y Llanto en el paraíso de Patricia Nieto
Authors: Puerta Molina Andrés Alexander , Laverde Román Alejandra María
Published: July 2023

La crónica es un género híbrido, entre el periodismo y la literatura, idóneo para representar el conflicto armado colombiano desde la perspectiva de las víctimas. Puede considerarse una de las narrativas experimentales propuestas por Dominik LaCapra para explorar procesos postraumáticos documentados por la historiografía, que contribuyen en la elaboración del duelo y permite a los lectores una mayor comprensión de la violencia a partir de la empatía. Por ello, se analizan los recursos narrativos utilizados por Patricia Nieto en los libros Los escogidos y Llanto en el paraíso, a luz de las propuestas de LaCapra. La lectura descriptiva e interpretativa se contrasta con el tratamiento del tema en la narrativa de la Violencia y el estudio del contexto histórico de Colombia para entender cómo los textos analizados logran construir memoria de la violencia y dan cuenta de la experiencia de las víctimas del conflicto en su complejidad humana y no como parte de las estadísticas.
Las razones de un destierro: a propósito de las acusaciones de Alexandra von Teuffenbach contra el fundador de Schoenstatt
Authors: Serrano del Pozo Ignacio
Published: July 2023

El objetivo de este trabajo es problematizar la lectura que Alexandra von Teuffenbach ha hecho sobre el actuar del sacerdote alemán Joseph Kentenich, a quien denuncia por haber cometido abuso de poder, abuso espiritual y emocional contra un grupo de Hermanas de María en los años 50. De acuerdo con la investigadora, una revisión de los expedientes vaticanos daría cuenta de que la razón por la que Kentenich habría sufrido un exilio durante 14 años fuera de Schönstatt, correspondería a una medida del visitador pontificio, el jesuita neerlandés Sebastian Tromp, para proteger a la comunidad de mujeres consagradas contra su abusador.  El propósito de este artículo es mostrar que la cuestión juzgada por el Santo Oficio se mueve en otro plano, el que se debiese abordar desde una hermenéutica más objetiva que haga justicia a las palabras utilizadas en los documentos oficiales, así como a las mismas expresiones emitidas por el encargado de la visitación.  En esa línea, se analiza en este trabajo la crítica dirigida por Tromp a la espiritualidad de Schoenstatt y de su fundador por falso misticismo, falso culto personal y falsa dirección espiritual. Para este trabajo se ha utilizado la reciente edición de los informes apostólicos publicados por Patris Verlag, archivos sobre los que sólo recientemente se ha levantado su embargo como parte de los documentos del pontificado de Pío XII.
Un desenlace antimaniqueísta en el Himno a san Demetrio (nº 71) de Romano Melodo
Authors: Urbano-Ruiz Miriam
Published: July 2023

El Himno a san Demetrio (nº 71) de Romano Melodo presenta en su desenlace de la historia del martirio un excursus sin relación alguna con la leyenda del santo y las versiones de su hagiografía que traslada a los fieles oyentes un sentir eminentemente antiherético, en concreto, antimaniqueísta. En este artículo se propone una traducción a la lengua castellana de dicho fragmento griego y se analiza la digresión por parte del autor del texto hímnico, tratando de arrojar luz sobre el contexto de producción y ejecución del kontákion en honor del santo tesalonicense.
Unusual Communication between Nerve to Mylohyoid and Lingual Nerve and, its Clinical Significance- A Cadaveric Study
Authors: Sharma Bali , Patel Roma , Parate Swapna , Saini Neha
Published: July 2023

Introduction: The nerve to mylohyoid is a branch of inferior alveolar nerve which arises just above the mandibular foramen. There is occasionally communicating branch between nerve to mylohyoid and lingual nerve. Knowledge of such variations has significance during oral and submandibular surgery. Aim: To detect and describe the existence and occurrence of anatomical variations in the innervation pattern of the nerve to mylohyoid by using the dissection technique. Materials and Methods: An observational study was carried out from January 2022 to April 2022 in a total of 15 embalmed and formalin-fixed cadavers in the Laboratory of Anatomy of SMBT Medical College, Nashik, Maharashtra. The nerve to the mylohyoid and lingual nerve were cleared and observed for any unusual communication between the two, if any. Results: In 13 (86.67%) cadavers, classical (normal) anatomical presentation of the nerve to mylohyoid was observed, whereas, in two male (13.33%) cadavers, the presence of communicating branch between the nerve to mylohyoid and lingual nerve was observed. In both the cadavers, the communicating branch was unilateral, in one cadaver on the right-side, and in the second cadaver same variation was noted on the left-side. Conclusion: The existence of communication between the nerve to mylohyoid and the lingual nerve is thought to be responsible for inadequate mandibular anesthesia. Through this study, surgeons will be aware of this variance, to explain unexpected findings in nerve injury following oral procedures.
Histopathological Variants and Molecular Subtypes of Carcinoma Breast in a Tertiary Care Centre, Kerala, India: A Cross-sectional Study
Authors: Raju Anjali , Raman Jayasree , Ravi Kavitha
Published: July 2023

Introduction: Breast cancer is the second leading cause of cancer deaths in women after lung cancer. Breast cancer survival varies by racial and ethnic factors, stage at diagnosis, tumour grade, molecular subtypes and the treatment received. Molecular subtyping provides prognostic and predictive information about the risk of recurrence and is an essential tool in formulating guidelines in therapy. Aim: To identify the histopathological variants of Carcinoma (Ca) breast in women and to determine the various molecular subtypes by Immunohistochemistry (IHC). Materials and Methods: A cross-sectional study from January 2019 to December 2020 was done on 100 cases of invasive carcinoma breast at the Department of Pathology in a tertiary care center of Government Medical College, Ernakulam, Kerala. IHC was done on paraffin processed tissue sections of tumour using anti-Oestrogen Receptor (ER), anti-Progesterone Receptor (PR), anti-Human Epidermal growth factor Receptor 2 (HER2/ neu) and Ki-67 antibodies. Molecular subtypes of Luminal-A, Luminal-B, HER2 enriched and triple negative (basal-like) were determined. The association between molecular subtypes and tumour grade, size, stage was analysed using IBM Statistical Package for the Social Sciences (SPSS) version 21.0 software. Chi-square test used for categorical variables, p-value <0.05 assumed to be significant. Results: Total 100 female cases of invasive carcinoma breast with mean age 49.3±12.2 years were included. Histologic subtypes of carcinoma were: Invasive Ductal Carcinoma (IDC) of No Special Type (NST) (89%), Invasive Lobular Carcinoma (ILC) (1%), Invasive ductal with Lobular carcinoma (IDC-L) (1%), metaplastic (2%), papillary (4%), IDC with medullary like features (3%). Tumour size was pT1 in 27%, pT2 in 38%, pT3 in 33%, pT4 in 2%. Tumour grades were: grade-I (28%), grade-II (29%) and grade-III (43%). Lymph node metastasis was seen in 52% cases. Positive expression of Oestrogen (ER) in 46%, Progesterone (PR) in 38%, HER2/neu in 23% and low Ki-67 labeling index (<14%) in 32% cases were observed. The molecular subtypes were Luminal-A (32%), Luminal-B (14%), HER2 enriched (16%) and triple negative (38%) in the present study. Conclusion: The most common molecular subtype was triple negative. Luminal-A subtype was associated with lower histologic grade and non luminal subtypes were associated with higher histologic grades. To determine molecular subtypes, IHC is useful as a surrogate for molecular testing.
USE OF APAMARGA KSHARSUTRA IN THE MANAGEMENT OF WART (CHARMAKEELA): A CASE STUDY
Authors: Gadve Babasaheb N. , Wagh Kiran D.
Published: July 2023

Introduction: Warts, also known as Verrucae, is a common dermatological condition caused by Human Papilloma Virus (HPV). A wart is generally a small, rough growth typically on human hands or feet but often in other locations that can resemble a cauliflower or a solid blister. According to Ayurveda, this ailment can be compared with Charmakeela, one of the kshudrarogas. Case presentation: A 65-year-old male patient visited OPD complaining of pedunculated growth over the left thigh region, occasionally feeling itching and discomfort at the growth site. Routine blood and urine examination were done and found within normal range. Diagnosis and management: Based on clinical features, the case was diagnosed as a wart (Charmakeela) and suggested for a Ksharasutra ligation procedure on an OPD basis. Treatment aims to destruct hyperkeratotic overgrown skin and to avoid recurrence. Outcome: There was marked improvement in the wart after Ksharasutra ligation; gradually, the wart detached from its base, leaving a minimal scar. Discussion: Satisfactory results were obtained. This case highlights that Ksharasutra ligation is a very effective and invasive procedure and one of the potential treatments for managing warts.
MANAGEMENT OF KHALITYA WITH MALATYADI TAILAM: A CASE STUDY
Authors: Nimbarte Bhairavi , Kokate Pratibha , Wate Priyanka
Published: July 2023

Hair fall is a universal problem, affecting both sexes of all races. Ayurvedic remedies are popular for men and women with hair loss because they incorporate natural ingredients and have been an effective cure for hair fall since ancient times. In Ayurveda, Khalitya (Hair fall) comes under the title of Shiroroga (diseases of the head) and Kshudraroga (minor skin diseases). Excessive intake of tea, coffee, alcohol, fried food, spicy food, overstress, improper hair care, excessive use of synthetic hair care products, hot climatic conditions, and continuous exposure to dust are the common causes of Khalitya. A 19-year-old female patient came to OPD of the department of Kayachikitsa with chief complaints of Khalitya (Hair fall), kesha rukshata (dryness of hair) and kesha tanutva (thinness of hair) on the left frontal side of the scalp. Malatyadi tailam was advised for external application and general hair care in this case. Malatyadi tailam is an Ayurvedic formulation prepared from medicinal herbs and coconut oil. Progress provided by this remedy was assessed based on the signs and symptoms of the patient before and after the treatment. Abhyanga (head message) using Malatyadi tailam showed significant improvement in blood circulation, natural growth and shine of the hair.
ROLE OF SHODHANA IN THE MANAGEMENT OF UNEXPLAINED INFERTILITY: A CASE REPORT
Authors: DH Ajisha
Published: July 2023

Unexplained infertility refers to a diagnosis made in couples in whom standard investigations, including semen analysis, ovulation testing, and tubal patency, yield average results. A 29-year-old woman who had had trouble conceiving for three years got admitted. She has had regular menstruation cycles since she was 17, and bleeding usually lasts 4-5 days. Her secondary sexual signs were typical, and there was no evidence of any other systemic disease. So, treatment was planned based on the concept of kshetra shudhi (purification of the uterus). The patient was of Vata Pitta prakriti (Vata Pitta constitution), and considering kala (season) and other factors, vamana (emesis) and virechana (purgation) was planned. Vamana karma (emesis) is done with Madanaphaladi yoga (Randia dumeorum medicines) after doing snehapana (intake of medicated ghee) with Indukantham ghrita. Virechana (purgation) was done with Manibhadra gulam after doing snehapanam (intake of medicated ghee) with Kalyanaka ghrita. The patient conceived soon after her first menstrual cycle and delivered a healthy baby girl. The kshetra (uterus) should be devoid of the morbid dosha for conceptions. Vamana (emesis) and virechana (purgation) have action all over the body, and so it does kshetra shudhi (purification of the uterus).
MANAGEMENT OF BHAGANDARA (FISTULA-IN-ANO) WITH KSHARASUTRA AND PANCHAVALKALA KASHAYA SITZ BATH: A CASE SERIES
Authors: Kamate Premalata , Metri Chandu , Patil Giramalla
Published: July 2023

Sushruta Samhita describes Bhagandar (Fistula-in-Ano) as one of the Ashtamahagada (the eight major diseases). This disease is recurrent, which makes it more challenging to treat. So, it causes inconvenience in routine life. The concept of the Ksharasutra has been explained in the context of Nadi vrana (sinus) by Acharya Sushruta. Hippocrates has explained the application of plain silk thread for the Fistula-in-Ano. Ksharasutra, being a medicated thread prepared per the standard protocol, has been proven to be a big revolution in treating Fistula-in-Ano. The Ksharasutra plays an important role, and its efficacy has been explained in various studies. In the present case series, we present here 5 different Bhagandar manifestations, managed with shamana aushadhis, Ksharasutra, anulomana (laxative effect), and panchavalkala sitz bath. The patients were treated on an OPD basis with a weekly thread change. The patients recovered well with complete tract excision within 6-12 weeks. Treatment of Fistula-in-Ano with Ksharasutra is a simple technique with low complications, less reoccurrence, and is cost-effective. Thus, Ksharasutra is very effective with the minimum invasive surgical modality for managing Bhagandara (Fistula-in-Ano).
CASE STUDY ON EXPLORATION OF AYURVEDA POTENTIAL IN POTT’S TUBERCULOSIS
Authors: Nandhini H Hema , Rajamurugan R , Nivetha J Stephy
Published: July 2023

Tuberculosis remains the world’s deadliest infectious killer despite the availability of highly efficacious treatment for decades and is one of the top 10 causes of death worldwide. Treatment of TB in the Ayurvedic system poses a difficult challenge to the Ayurvedic physician. The objective of this study is to discuss the case of a Pott’s spine patient. We conducted a Case report study. We included a report of a confirmed case of Pott's spine, which, after twelve months of regular Ayurvedic treatment, recovered clinically and radiologically from the disease. The patient had an infection with Mycobacterium tuberculosis, as revealed by the culture of the drained abscess. The MRI of the thoracic and lumbar spine of the patient showed discitis of the D12-L1 discs with osteomyelitis involving vertebral bodies from D8 to L1. Ayurvedic concepts that include nutritional support, palliative care, and detoxification therapy form the foundation of the treatment of TB. The overall recovery of the patient from such a destructive disease was excellent.
AN ETHNO-MEDICINAL REPORT ON ARISTOLOCHIA INDICA L. (ISHWARI) USED IN UDALGURI DISTRICT, ASSAM, INDIA
Authors: Chakraborty Priyanka , Bora Devanjal , Kemprai Kapil Kumar , Khersa Bimisa , Baruah Dinesh
Published: July 2023

Background: Ethnomedicine allows medicinal plants to cure disease combined with traditional health medicine (Ayurveda) for better healthcare worldwide. Ayurveda, the ancient traditional system of medicine in India, focuses on the natural way of managing and preventing diseases. Similarly, ethnic communities depend highly on medicinal plants in their vicinity for healthcare. Folk medicine and Ayurveda are being imbricated to each other regarding treating ailments. Objectives: The study aimed to explore and document a new claim in Udalguri district, Assam. Material and Methods: An ethnomedicinal study was carried out in September 2022 among the local inhabitants of the study area. Traditional healers and local people practising folk medicine were approached for documentation of folk uses. Result: A new ethnomedicinal report of Aristolochia indica L. (Aristolochiaceae) used by the Bodo community from Udalguri district in Assam against insect bites is reported in the present communication. The use of leaf in this claim has not been previously reported from Assam. Conclusion: Comprehensive justification with the help of Ayurveda and ethnopharmacology has been given to verify the efficacy of the plant and the folk claim against insect bites.
ASSESSMENT OF VARNA AND SPARSHA-RELATED ARISTA LAKSHANA IN CRITICALLY ILL PARTICIPANTS
Authors: . Divyarani , Ismail HM , Zenica D’Souza
Published: July 2023

This study aimed to explore and assess varna (colour) and sparsha (touch) related arista lakshana (imminent signs of death) in critically ill participants and co-relate them to the prognostic outcomes in the current medical scenario. Critical illness is a condition associated with many variables and unpredicted factors. Hence assessment of prognosis is essential for making a medical decision before treatment, as well as revealing the patient’s prognosis to their family members in the earliest and most effective manner. Ayurveda explains prognosis in the context of sadhya-asadhyatha and arista lakshana. Yet there is a need to explore the relevance of arista lakshana mentioned in Ayurveda texts in current medical practice and give an evidence-based scientific rationality to it. Therefore, this study was conducted. This study was conducted on twenty-six critically ill participants admitted to the MICU of a renowned medical college hospital, presenting with arista lakshana pertaining to varna or sparsha or both, as explained in Charaka Samhita, irrespective of their disease diagnosis. The study revealed that a maximum number of arista lakshana related to varna and sparsha were found in participants of the age group 41 to 60 years. Incidence of black discolouration and abdominal distention as arista lakshana were the highest; participants had a demise which accounted for 19.20%. Hence the study concluded that assessing dosha, dushya, srotas, rogamarga, and arishta lakshana in critically ill participants holds a significant place even in the present scenario.
EFFICACY AND SAFETY OF "SACHI SAHELI" POLYHERBAL FORMULATIONS IN GYNAECOLOGICAL DISORDERS: A PROSPECTIVE, NON-RANDOMISED, OPEN-LABEL STUDY
Authors: Kimtata Vijay , Gupta Vishu , Singh Lakhbir , Ahmed Hasan Ali , Kamuni S Radhika
Published: July 2023

Background and aim: Symptoms of gynaecological disorders, including dysmenorrhea, leukorrhea, and premenopausal syndrome (PMS), are a common health concern, particularly among women of reproductive age. Due to the adverse effects of conventional treatments, the use of herbal remedies to treat various gynaecological disorders has increased. This study aimed to assess the efficacy and safety of Sachi Saheli formulations in subjects suffering from dysmenorrhea, leucorrhoea, and PMS. Methods: This was a single-arm, open-label, non-randomised prospective study. Female participants were recruited based on the inclusion and exclusion criteria. Study interventions were given to all participants for 90 days. Changes in blood haemoglobin levels were assessed from the baseline to the end of the study. Subjective symptoms and the investigators' severity assessment on 27 questionnaires were evaluated at baseline and the end of the study. Safety was also assessed by measuring liver and kidney function's haematological and biochemical markers. Results: A total of 120 female subjects were enrolled. After treatment with Sachi Saheli syrup and tablets, blood haemoglobin levels increased significantly compared to baseline (p < 0.0001). All subjects showed significant improvement in anxiety, menstrual pain, depression, and vaginal discharge symptoms. A significant improvement in the severity of physical and affective symptoms across 27 parameters was also observed. There were no significant changes observed in laboratory safety parameters. None of the subjects reported any adverse events during the treatment period. Conclusions: Sachi Saheli syrup and tablet may improve the symptoms of dysmenorrhea, leukorrhea and PMS.
EVALUATION OF COMBINED EFFECT ON ANTIHYPERLIPIDAEMIC ACTIVITY OF MADHUCA LONGIFOLIA AND BUTEA MONOSPERMA L. IN TRITON WR-1339 INDUCED HYPERLIPIDAEMIC RATS
Authors: Shrirao AV , Rahman M Muqitur , Mahure PD , Kochar NI , Chandewar AV
Published: July 2023

The use of herbal remedies in India has a long history for various medical conditions. High serum total cholesterol, low-density lipoprotein (LDL) concentrations, and a decline in high-density lipoprotein are the main risk factors for coronary heart disease. It has been observed that Butea monosperma L. flower extract and Madhuca longifolia bark extract have been used traditionally to treat hyperglycaemia and related hyperlipidaemia. The evolution of atherosclerotic plaques and coronary artery disease are known to be accelerated by hyperlipidaemia. In the current study, hyperlipidaemic rats were used as a model to examine the potential antihyperlipidemic effects of a hydroalcoholic extract of Butea monosperma L. flowers (HA-BM) and Madhuca longifolia bark (HA-ML). Triton WR 1339 (400 mg/kg) was administered intraperitoneally (i.p.) once to rats to cause hyperlipidaemia, which resulted in rats with persistently high serum levels of triglycerides and cholesterol. The combined dose of HA-BM (200, 400 and 600 mg/kg/day) and HA-ML (250, 500 and 750 mg/kg/day) at a ratio of 1:1 was given to normal and hyperlipidaemic rats. Serum and liver tissue were analysed for lipid profile, and the activity was compared to the cholesterol-lowering drug, atorvastatin (10 mg/kg). From the above study, it could be concluded that a combined dose of an extract of Butea monosperma L. and Madhuca longifolia not only resulted in a significant reduction in cholesterol, triglyceride, LDL, VLDL level but also increased the HDL level, which is good for health.
A CROSS-SECTIONAL STUDY ON THE PROPORTION OF DEPRESSION, ANXIETY AND STRESS AMONG MADHUMEGAM (TYPE 2 DIABETES MELLITUS) PATIENTS
Authors: R Mohana , H Vetha Merlin Kumari , H Nalini Sofia , T Lakshmikantham , R Meenakumari
Published: July 2023

Background: The prevalence of depression, anxiety and stress is common among madhumegam (Type 2 Diabetes mellitus) patients. Association of depression, anxiety and stress increase the risk of madhumegam (Diabetes mellitus) and its complications and reduce the quality of life. Hence, this study aimed to assess depression, anxiety and stress among patients with madhumegam (Diabetes mellitus). Materials and Methods: The cross-sectional study was carried out among 100 patients those who purposively selected and clinically diagnosed madhumegam (Diabetes mellitus) attending Ayothidoss Pandithar Hospital, National Institute of Siddha, Tambaram Sanatorium, Chennai. The patients were selected by inclusion and exclusion criteria and interviewed using a pre-designed DASS 21 Questionnaire. Data were analysed by using inferential statistics. Results: Out of 100 patients, 23% of patients had depression, 30% of patients had anxiety, and 12 % of patients had stress. Conclusion: Patients with madhumegam (T2DM) had significantly high rates of depression, anxiety and stress. Hence, regular screening of Diabetes Mellitus patients for psychological distress is recommended, along with a diabetes management plan for early identification and treatment.
A CROSS-SECTIONAL STUDY ON THE FREQUENCY OF KURAIVEETHANA NOI (SUBCLINICAL AND CLINICAL HYPOTHYROIDISM) AMONG CHRONIC KIDNEY DISEASE PATIENTS
Authors: Shree PJ Kowsika , Kumari H Vetha Merlin , Nalinisofia H , Lakshmikantham T , Kumari R Meena
Published: July 2023

Background: Thyroid hormones have a major role in renal development and physiology. It has been shown that in chronic kidney disease (CKD), as the Glomerular Filtration Rate (GFR) falls, there is a higher possibility of developing clinical and subclinical hypothyroidism (SCH). With falling GFR, several abnormalities are growing in the thyroid gland at both structural and functional levels. Objective: To estimate the frequency of kuraiveethana noi (subclinical and clinical hypothyroidism) among CKD patients through lab investigation (Thyroid Function Test). Materials and Methods: It is a cross-sectional study carried out on 50 CKD patients reporting at the National Institute of Siddha using a non-random sampling method. After obtaining informed consent, Blood samples were collected from each patient to document their Thyroid profile. Results: Based on their report of thyroid profile, 19 patients had subclinical hypothyroidism, and 6 patients had clinical hypothyroidism. Conclusion: The study concludes that the frequency of subclinical and clinical hypothyroidism is found to be 38% (19 patients) and 12% (6 patients), respectively, among 50 chronic kidney disease patients who visited OPD of Ayothidoss Pandithar Hospital, National Institute of Siddha, Tambaram sanatorium.
A REVIEW ON LONI (PORTULACA OLERACEA L.) IN KIDNEY DISEASES: A BOON FROM NATURE THROUGH AYURVEDA
Authors: Chakraborty Priyanka , Bora Devanjal , Baruah Dinesh
Published: July 2023

In today’s era, medicinal plant resources are constantly depleting due to destructive harvesting. The scarcity of medicinal plants has put a threat to Ayurveda. The plants found in the ecology have certain positive effects on our human body, which remain to be disclosed and discovered. Diet is also important in fighting the disease. Kidney disease can only be managed not only with medicines but also with a proper diet plan. Out of innumerable medicinal and edible plants, Loni (Portulaca oleracea L.) is one of them which possesses innumerable therapeutic benefits. The study aims to procure the uses of Loni (Portulaca. oleracea L.) in kidney diseases and determine if it can be used as a diet for the above disease. The study has been carried out based on modern phytochemistry, modern and Ayurvedic pharmacology keeping in view of Ayurvedic classics like Kaiyadeva Nighantu, Bhavaprakasa Nighantu, etc. of Loni (Portulaca oleracea L.) along with other experimental and evidence-based research papers. Purslane has massive action in delaying the progression of kidney disease through its nutritional benefits and value and its anti-nephrotoxic activity, which are being discussed in modern and Ayurvedic science. In managing kidney disease, the study has suggested that Loni (Portulaca oleracea L.) can be added as an edible vegetable as part of the diet plan.
TREATMENT MODALITIES IN TREATING AMA CONDITIONS WITH SPECIAL REFERENCE TO AUTOIMMUNE DISEASES: A REVIEW
Authors: Surekha O. , Swaroopa A. , Babu P. Srikanth
Published: July 2023

The main fundamental concept of Ayurveda is to preserve the health of a healthy person and cure the disease of an unhealthy person, i.e., prevention and cure. Acharya Charaka has enumerated various rasayana at the very beginning of chikitsa sthana, which explains the role of prevention that comes prior to cure in Ayurveda. In autoimmunity and their diseases, where the cause is unknown, a person's immune system reacts to self-proteins causing various inflammations, fevers, etc., destroying body tissues and changes in organ functioning, leading to more significant morbidities over time. While treating these conditions, the primary objective of a physician should be relieving the patient’s symptoms and correcting the imbalance created in his immune system without further compromising it. Here comes Ayurveda, the ancient holistic science of life, where acharyas have provided various formulations, purificatory mechanisms, and rejuvenator elixirs in treating such exasperating diseases with the concept called “Ama” by correcting the agni the Élan vital of life. The imperfectly digested anna rasa due to impaired agni is known as ama. The present article lists all possible treatments for treating sama conditions with special reference to autoimmune diseases.
A REVIEW ON PALITYA AND DHATRYADI RASAYANA
Authors: Rani Sheenam , Sharma Usha , Singh Sanjay Kumar , Sharma Khem Chand
Published: July 2023

Hair is a valuable anatomical structure of the body, having cosmetological and sociological importance in drafting the beauty and personality of an individual. Greying of hair represents the sign of ageing known as Palitya in Ayurveda. But when hair starts greying before the usual age of onset, known as premature greying of hair. Premature hair greying is called Akalaja Palitya, which occurs due to various factors resulting in the vitiation of Pitta dosha. Due to mankind’s hectic, sedentary and busy schedule, the current scenario is witnessing several challenges, and premature greying of hair is one among them. Premature hair greying has multifactorial aetiology, including oxidative stress, nutritional deficiency, smoking, and dysfunctional thyroid hormones, but the exact aetiology is still unknown. Acharyas have mentioned various rasayana for preventing and treating premature hair greying, i.e., Akalaja Palitya. Rasayana therapy aims primarily to promote the strength and vitality of the body. It also helps maintain the integrity of sapta dhatus (fundamental structural component) by improving digestive power resulting in the sound production of successive dhatus and their malas. Dhatryadi rasayana is a polyherbal formulation consisting of three ingredients, i.e., Dhatri (Emblica officinalis Gaertn.), Bhringraj (Eclipta alba Hassk.) and Tila (Sesamum indicum Linn.). All three plants have the keshya property. Emblica officinalis Gaertn. and Sesamum indicum Linn. both act as a 5α-reductase inhibitor. Eclipta alba Hassk. stimulates the proliferation of follicular keratinocytes by downregulating the TGF-β1 (Transforming Growth Factor Beta 1) expression. Furthermore, all ingredients of Dhatryadi rasayana have antioxidant properties and contribute to essential nutritional supplements required for proper hair development and growth.
PHYSIOLOGICAL ASPECT OF TWACHA VARNA: A REVIEW
Authors: D Vyas Suwarna , M Vyas Deepak , P Waghmare Pragati , . .
Published: July 2023

Now a day, Ayurveda is gaining wide popularity in the field of cosmetology. Many cosmetic products are prepared and used on the Ayurvedic concepts. Twacha is matruj bhava. The foetus gets varna in the sixth month of intrauterine life. The word "varna" means lustre of the body. Varna is not just colour but includes all the parameters of healthy and radiant skin. Twacha varna varies among different individuals. In Ayurveda twacha varna occurs as per prakriti. According to current medical science, skin colour depends on the amount of melanin and other factors. So here is an attempt to enlist all the factors responsible for varnotpatti.
KHADHIRASADHITHA THUVARAKA RASAYANA: A REVIEW
Authors: Patil Giramalla , Medikeri Surekha , Patil Shivanand
Published: July 2023

Rasayana is a specialised technique that includes rejuvenating recipes, nutritional regimens, and behaviours to boost one's health. Scientific studies have proven its usefulness in managing chronic lifestyle-related illnesses and degenerative alterations. Thuvaraka rasayana is an Ayurvedic herbal formulation that promotes overall health and well-being. Chaulmoogra oil is used internally and externally in Ayurvedic medicine to treat skin diseases. Khadhirasadhitha Thuvaraka Rasayana is a specialised preparation explained by Sushruta acharya mainly in the management of Kushta and Prameha as Naimittika rasayana in different doses based on roga and rogibala. As the Thuvaraka has the ubhaya marga doshaharana property, its utility is well established based on Ayurvedic principles in the management of Kushta, as in this disease, there is a need for repeated shodhana. The Thuvaraka Rasayana regimen is one such modality where doshaharana and Rasayana benefits are achieved at the same time.
A REVIEW OF BHUMI DESHA [GEOGRAPHICAL LAND] AND ITS EFFECT ON DIFFERENT PARAMETERS
Authors: Anupam Akansha , Gupta Arvind Kumar
Published: July 2023

In Ayurveda, desha refers to bhumi desha [geographical land] and atura desha [patients]. Both of them are interrelated and have been extensively described in the classics. A geographical land is characterized by the type of soil, which plays a vital role in climate, water cycle, rainfall etc. These are a few essential factors needed for the survival of humans. Bhumi Desha is one such factor which influences the health and disease of an individual. Knowledge of the place in which a person is born helps in determining its strength, while knowledge of the place where the person is living determines the susceptibility to disease occurring. Understanding the geographical land gives an extensive idea about the properties of drugs. Desha plays a vital role in the causation of epidemic, endemic or pandemic disease. Three types of geographical lands are described in Ayurveda jangal desha [dry lands], anupa desha [wetlands] and sadharana desha [mixed dry and wet land]. The three biological entities Vata, Pitta and Kapha dosha of an individual have an extensive relationship with these lands. bhumi desha and atura desha are interrelated, affecting the latter in many areas.
A REVIEW ON INTEGRATED APPROACH IN CHILDHOOD MALIGNANCIES-PREVENTION AND CONTROL
Authors: Rathi Kavita , Sharma Brahm Dutt , Ojha Nisha Kumari
Published: July 2023

Introduction: Cancer has become a huge concern since it is the second-leading cause of death in poor nations and the primary cause in economically developed countries. According to the WHO, cancer has become the deadliest killer in the world and is one of the deadliest diseases of the twenty-first century. According to the World Health Organization, India accounts for at least 20% of the world's burden of paediatric cancer, with about 75,000 children diagnosed with the disease annually. According to the Indian Council for medical research, 5.5% of all cancer cases in India include youngsters. Paediatric cancer may primarily be examined under three categories: before conception, throughout pregnancy, and after delivery, according to the adhyatmika vyadhi categorization of illness. According to the current paradigm, DNA alterations that occur early in a child's life cause cancer, which is caused by inherited mutations from parents that raise the chance of cancer in children. Some preventative methods, including dinacharya, ritucharya, rasayana, shodhana, and garbhini paricharya, are explained by Ayurveda. The condition that resembles cancer is described as Granthi and Arbuda in the classical texts of Ayurveda. The purpose of this study to find out the integrated approach in childhood malignancies-prevention and control.
IMPORTANCE OF RASOUSHADHIS IN AYURVEDA: A REVIEW
Authors: Sharma Shiwali , Sharma Usha , Mitra Shuchi , Sharma Khem Chand
Published: July 2023

If used wisely, science is a boon to humanity and, if misused, can be hazardous. Ayurveda is one of the primordial systems of medical science that has elaborated the causes and methods of drug-induced consequences and preventive measures. Every system has some flaws, which need to be noted and rectified no matter how excellent the system is. In rasoushadhis (herbomineral formulations) preparation, specific techniques like shodhana, jarana and marana etc., have been developed to prepare more bio-assimilable forms of rasaushadha dravya. The indications, dose, vehicle, period of drug administration, interval or duration of treatment, diagnosis of the disease, nature or prakriti of the patient, pathya-apathya (favourable-unfavourable regimen) etc., are significant factors that the physician should always consider before they recommend these rasoushadhis to the patients. This review compiles the standard procedures which are adopted during the preparation of rasoushadhis like Shodhana, and Marana, the utility of rasoushadhis in Ashtanga Ayurveda, skin diseases, lifestyle disorders etc. and the rational use of rasoushadhis to understand and highlight the importance and uniqueness of rasoushadhis.
Knowledge of Farmers towards Adoption of Grape Cultivation for Wine Making in Champhai District, Mizoram
Authors: Lalramdinthara Alex , Bose Dipak Kumar
Published: July 2023

Grape cultivation plays a significant role in India, contributing to its economy, nutrition, and employment opportunities. Specifically, grape cultivation for wine production holds great importance, both economically and in terms of farmers' attitudes. This study was conducted in Champhai town, Mizoram, to explore the social and psychological factors that influence the acceptance of large-scale wine making. Descriptive research design was followed for the present study. The findings of this research showed that the majority of respondents in the study belonged to the middle age group (36-55), had a basic level of education, predominantly from nuclear families and farming was their primary occupation. The study found that most respondents had moderate levels of scientific orientation, mass media exposure, progressiveness, and extension contacts. In terms of knowledge, 15% of respondents demonstrated a high level, while 52.50% had a moderate level, and 32.50% had a low level of knowledge about grape cultivation practices. Age, education, occupation, extension contacts, mass media exposure, family type, family size, source of information utilized, progressiveness, and scientific orientation were identified as factors influencing knowledge. The major constraints identified were the heavy attack of pests, diseases, nematodes, and weeds, as well as inadequate management of fertilizers and pesticides.
Effects of Process Parameters on Clay-Catalyzed Rice Husk Hydrolysis
Authors: Chukwuma Nkanyi Obidi , Nwabanne Joseph Tagbo , Okey-Onyesolu Chinenye Faith , Chukwujindu Nnabuike Christian
Published: July 2023

In order to catalyse the transformation of the cellulose from rice husks into reducing sugars, clay was subjected to thermal treatment, HCl treatment, and NaOH treatment. This work aims to produce bioethanol from rice husk using a clay catalyst. Using proximate analysis and elemental analysis, rice husk was characterised in order to identify its composition. Response Surface Methodology (RSM), based on Central Composite Rotatable Design (CCRD), was used with design expert software to statistically optimise the process conditions. The maximum glucose yield of 22.18%, 20.58%, and 20.02% was realized when hydrolysis of rice husk was carried out with NaOH, thermal, and HCl treated clay, respectively. The numerical optimization with CCRD to maximize sugar yield gave 19.32% at 53.73 mins for alkaline treated clay and 16.76% at 46.48 mins for acid treated clay. Based on the findings of this research, alkaline treatment of clay for the hydrolysis of rice husk has demonstrated to produce the maximum glucose production when compared to acid and thermal treatment of clay.
Analysis of Determinants of Cooperative Profit in Indonesia
Authors: Ma'ruf Ahmad , Amalia Nabila Nur
Published: July 2023

This study aim knows influence and differences in business volume, own capital, outside capital and amount member to cooperatives profit in Indonesia before the Covid-1 pandemic and time Covid-19 pandemic with use quantitative method analysis used is multiple linear regression and paired T-test using SPSS software. Data in the form of business volume, own capital, external capital, total member cooperatives in 34 provinces in Indonesia. The results of the analysis that has been done obtained results that business volume 2019 is influential positive and no significant to cooperatives profit with mark Sig 0.453 and coefficients of 0.039. business volume 2021 matters positive and significant to cooperatives profit with mark Sig 0.002 and coefficients of 0.198. Own capital 2019 is influential positive and significant to cooperatives profit with mark Sig 0.000 and coefficients of 0.278. Own capital 2021 matters positive and no significant to cooperatives profit with mark Sig 0.673 and coefficients of 0.026. Outside capital 2019 is influential positive and no significant to cooperatives profit with mark Sig 0.185 and coefficients of 0.067. Outside capital 2021 matters negative and no significant to cooperatives profit with mark Sig 0.156 and coefficients of -0.080. Amount member 2019 is influential negative and significant to cooperatives profit with mark Sig 0.000 and coefficients of -0.239. Amount member 2021 matters positive and no significant to remainder results business with mark Sig 0.642 and coefficients of 0.041. There is a difference in business volume, own capital, outside capital and amount members in Indonesia cooperatives before and after the Covid-1 pandemic.
Water Audit Assessment and Evaluation of Physicochemical Parameters of Water in Haibat Mau Mawaiya, Raibareli Road, Lucknow, India
Authors: Gangwar Isha
Published: July 2023

The present study deals with quantitative and qualitative analysis of water. Water is essential for life on Earth, and it has finite resources in the world. Water resources are very beneficial to humans, and beyond human uses, they have a crucial role in every living creature. Nevertheless, as the population increases and moves, the accessibility of quality and quantity of water systems declines. For quantitative analysis, a water audit was conducted in the Indrapuri colony of Haibat Mau Mawaiya locality, Lucknow, India. The water audit gives a balanced, scientific framework that classifies a system’s exclusive use of water and controls problems associated with drought, losses, leakage, and shortage. The quality of water indicates the condition of water concerning its suitability for a designated use like drinking, bathing, and so on. The qualitative analysis was done by taking several physicochemical parameters of water. If these parameters do not meet the standards, further preventive measures are required for social well-being and good economic health. Standards of water quality make sure the appropriate use of water for different purposes like drinking, industrial, irrigation, etc. For social well-being and good economic health, water quality is vital.
Risk Taking Behaviour as Determinant of Entrepreneurial Aspiration of Undergraduates in Tertiary Institutions in Ekiti State, Nigeria
Authors: Oluseyi Oyerinde David , Abayomi Ojomo David
Published: July 2023

Aim: The continuous increase in the rate of unemployment among graduates of tertiary institutions in Ekiti State has been a source of worry for the government and the public.   Despite the series of courses taken on entrepreneurship during the period of their studies in the institutions, it was observed that many graduates could not establish their enterprises after graduation due to certain reasons. It was against this background that this study investigated the relationship between risk-taking behaviour and entrepreneurial aspiration of undergraduates as well as the difference in the risk-taking behaviour of male and female undergraduates towards entrepreneurship. 

Methodology: Descriptive research design of the survey type was adopted for the study. The population of the study was 7342 final-year students in all tertiary institutions in Ekiti State.  Simple, stratified and proportional random sampling techniques were used to select 400 students from faculties/schools across the three types of institutions in the state.  A self-constructed instrument tagged Risk Taking Behaviour and Entrepreneurial Aspiration Questionnaire (RTBEAQ) was used to collect the data for the study. The instrument was constructed on 4-point Likert scale statements. Three experts ascertained the accuracy of the items on the instrument. The reliability of the instrument was established through Cronbach's alpha after it had been administered to 40 students outside the sample for the study, which yielded a coefficient value of 0.86.  The reliability coefficient obtained for the instrument was considered high enough for the study. Data collected were analysed using Pearson's Product Moment Correlation and z-test.  All hypotheses formulated were tested at a 0.05 level of significance.

Results: Findings of the study revealed that there was a significant relationship between risk-taking behaviour (mean of 12.83) and entrepreneurial aspiration of undergraduates (mean of 80.92) with a p-value of 0.00, < 0.05.  Also, the finding of the study showed that there was a significant difference between risk taking behaviour of male (mean of 241.2) and female (mean of 256.1) undergraduates with p-value of 0.01< 0.0.05). 

Recommendation: It was recommended among other that adequate education should be given to undergraduates in tertiary institutions on risk-taking and entrepreneurial aspirations in a bid to prepare them for entrepreneurial activities in future. The quality of entrepreneurship education given across all tertiary institutions should be the same since all entrepreneurs are going to face the same challenges when engaging in entrepreneurial activities.
A Journey from Clinical Pharmacist to a Diabetic Foot Wound Care Pharmacist from India: An Experience from Amit Jain’s Institute of Diabetic Foot
Authors: Apoorva H. C.
Published: July 2023

Diabetes is a growing problem and so are its complications with diabetic foot being one of the commonest known complications. Diabetic foot is often associated with amputation that increases the morbidity and mortality. Often, multidisciplinary management consisting of prevention, education, examination, treatment etc and multidisciplinary team approach can provide favorable outcomes. One of the members among this multidisciplinary team has been a pharmacist in few of the expert diabetic foot Centre’s around the world. It is observed that, though spoken of their role in clinical practice, either such roles are limited or undervalued. Further, there are sparse publications that provides a clear-cut role, training, responsibility, and their experience in a diabetic foot team. This article provides an essential insight on the journey of one of the first diabetic foot wound care Pharmacist from India.
A New Pyrrole-2-carboxaldehyde Functionalized Chitosan-Cu(II) Complex-based Chemosensor for Iodide Anion in Aqueous Media
Authors: Olugbemi Samuel Adeolu , Adebayo Lateefah Olanike , Adewuyi Sheriff
Published: July 2023

Iodine is an essential ingredient in thyroid hormones of which both low and high intakes may cause thyroid disease. This study develops a Pyrrole-2-Carboxaldehyde functionalized chitosan-Cu(II) Complex [PCAFC-Cu(II)] chemosensor, for quick and easy detection of iodide ions from its aqueous solutions. PCAFC-Cu(II) complex was synthesized from a simple condensation reaction of chitosan (CS) and pyrrole-2-carboxaldehyde (PCA) along with an aqueous solution of copper(II) salt. The starting materials and the products were characterized by spectroscopic (FT-IR and UV-Visible), X-ray powder diffraction, and microscopic methods (Scanning Electron Microscopy). The PCAFC-Cu(II) colorimetric sensing of I- revealed a color change adduced to the formation of a hydrogen bond or deprotonation of the complex matrix. Colorimetric detection for I- ions was obtained with a detection limit (LoD) of 0.005 M and the complex has high specificity for I- ions detection from a solution consisting of several anions. The synthesized complex [PCAFC-Cu(II)] could serve as an on-site reagent for the qualitative detection of iodide ions.