bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementing an Agent-Based Modeling Approach for Protein Glycosylation in the Golgi Apparatus
Authors: Jetschni Christian , Götz Peter
Published: September 2023

Glycoproteins are involved in various significant biological processes and have critical biological functions in physiology and pathology by regulating biological activities and molecular signaling pathways. The variety of enzymes used in protein glycosylation and the wide range of diversity in the resulting glycoproteins pose a challenging task when attempting to simulate these processes in silico. This study aimed to establish and define the necessary structures to simulate the process of N-glycosylation in silico. In this article, we represent the process of glycosylation in the Golgi structure in an agent-based model with defined movement patterns and reaction rules between the associated proteins and enzymes acting as agents. The Golgi structure is converted into a grid consisting of 150 × 400 patches representing four compartments which contain a specific distribution of the fundamental enzymes contributing to the process of glycosylation. The interacting glycoproteins and membrane-bound enzymes are perceived as agents, with their own rules for movement, complex formation, biochemical reaction and dissociation. The resulting structures were saved into an XML-format, a mass spectrometry file and a GlycoWorkbench2-compatible file for visualization.
Optimization of Gasifying Agents in 3D Downdraft Gasification for Enhanced Gas Composition, Combustion, and CO2 Utilization
Authors: Mehmood Adil , Tahir Muhammad Wasim , Saeed Muhammad Azam , Arshad Muhammad Yousaf , Hussain Huma , Mularski Jakub , Niedzwiecki Lukasz
Published: September 2023

The depletion of fossil-based fuels, fluctuating fuel market, and environmental deterioration demand an aggressive approach towards the advancement of renewable energy technologies. By the time reliable technology for a clean and abundant energy supply is established, existing sources must be economized. Biomass gasification is the way forward in that direction. CFD modeling shows promise in the development of advanced gasification systems. A simplified 3D CFD model of a downdraft gasifier is developed to investigate the effect of gasifying agent composition on the quality of syngas. Simulation results are compared with published experimental data and found to be in reasonably good agreement. Mixing CO2 with a gasification agent is also investigated as a possible carbon capture and utilization (CCU) strategy. An air-steam mixture is used as a base-case gasification agent. Firstly, the effect of air-to-steam ratio on syngas composition is investigated. Secondly, the effect of oxygen and mixing CO2 with a gasification agent is investigated in two separate cases. A 50%-50% air-steam mixture is found to produce the best quality syngas. Oxygen is found to have a negligible impact on the quality of syngas. The air-steam-CO2 = 23%-50%-15% mixture is found to be optimum regarding syngas quality.
Advances in Ostrowski-Mercer Like Inequalities within Fractal Space
Authors: Vivas-Cortez Miguel , Awan Muhammad Uzair , Asif Usama , Javed Muhammad Zakria , Budak Hüseyin
Published: September 2023

The main idea of the current investigation is to explore some new aspects of Ostrowski’s type integral inequalities implementing the generalized Jensen–Mercer inequality established for generalized s-convexity in fractal space. To proceed further with this task, we construct a new generalized integral equality for first-order local differentiable functions, which will serve as an auxiliary result to restore some new bounds for Ostrowski inequality. We establish our desired results by employing the equality, some renowned generalized integral inequalities like Hölder’s, power mean, Yang-Hölder’s, bounded characteristics of the functions and considering generalized s-convexity characteristics of functions. Also, in support of our main findings, we deliver specific applications to means, and numerical integration and graphical visualization are also presented here.
Study on Abundant Dust-Ion-Acoustic Solitary Wave Solutions of a (3+1)-Dimensional Extended Zakharov–Kuznetsov Dynamical Model in a Magnetized Plasma and Its Linear Stability
Authors: Arshad Muhammad , Seadawy Aly R. , Tanveer Muhammad , Yasin Faisal
Published: September 2023

This article examines how shocks and three-dimensional nonlinear dust-ion-acoustic waves propagate across uniform magnetized electron–positron–ion plasmas. The two-variable (G′/G,1/G)-expansion and generalized exp(−ϕ(ξ))-expansion techniques are presented to construct the ion-acoustic wave results of a (3+1)-dimensional extended Zakharov–Kuznetsov (eZK) model. As a result, the novel soliton and other wave solutions in a variety of forms, including kink- and anti-kink-type breather waves, dark and bright solitons, kink solitons, and multi-peak solitons, etc., are attained. With the help of software, the solitary wave results (that signify the electrostatic potential field), electric and magnetic fields, and quantum statistical pressures are also constructed. These solutions have numerous applications in various areas of physics and other areas of applied sciences. Graphical representations of some of the obtained results, and the electric and magnetic fields as well as the electrostatic field potential are also presented. These results demonstrate the effectiveness of the presented techniques, which will also be useful in solving many other nonlinear models that arise in mathematical physics and several other applied sciences fields.
Structural, Morphological, and Optical Properties of Single and Mixed Ni-Co Aluminates Nanoparticles
Authors: Gingasu Dana , Oprea Ovidiu , Marinescu Gabriela , Calderon Moreno Jose Maria , Culita Daniela C. , Preda Silviu , Surdu Vasile-Adrian
Published: September 2023

A series including single and mixed Ni-Co aluminates was obtained using the precursor method, with malic acid as a ligand. The malate precursors (polynuclear coordination compounds) were isolated and characterized by Fourier Transform Infrared (FTIR), Ultraviolet/Visible/Near Infrared (UV–Vis–NIR) spectroscopy, and thermal analysis. The UV–Vis–NIR spectra of the synthesized complex compounds highlighted the presence of Co2+ and Ni2+ in an octahedral environment. The thermal decomposition of these precursors led to Co1−xNixAl2O4 (x = 0, 0.1, 0.25, 0.5, 0.75, 0.9, and 1) spinels. The effect of Ni2+ substitution on the structure, morphology, and optical properties of the obtained oxides was studied with the help of different characterization tools. XRD, FTIR, and Raman spectra evidenced the formation of the spinel phase. The size of the crystallites and the agglomeration degree of the particles decrease when the nickel content increases. The band gap (BG) value is not significantly influenced by the Ni substitution. The fluorescence spectra recorded for all samples show a similar pattern, but different intensities of the emission bands.
Pulmonary Arterial Hypertension in the Elderly: Peculiar Features and Challenges for a Proper Phenotyping Approach
Authors: Scagliola Riccardo , Brunelli Claudio , Balbi Manrico
Published: September 2023

(1) Introduction. Although pulmonary arterial hypertension (PAH) usually affects young people with a low cardiovascular risk profile, progressive epidemiologic changes have been providing a codified phenotype of elderly subjects with PAH and increased risk predictors for left heart disease. We therefore conducted a systematic review to describe the current knowledge and characteristics of elderly individuals with PAH and further insights concerning their prognostic outcomes and therapeutic response. (2) Methods. A search was conducted in PubMed, Embase, and Cochrane Library for publications evaluating the epidemiology, diagnostic work-up, and treatment of PAH in elderly subjects. (3) Among the 74 publications initially retrieved, 16 full-text articles were selected for the present systematic review. Compared to their younger counterparts, elderly individuals with PAH showed greater clinical deterioration, reduced exercise capacity, and worse prognostic outcomes, as well as less response to PAH-targeted therapy and higher rates of PAH drug discontinuation. (4) Conclusions. Demographic changes over time contributed to define a peculiar PAH phenotype in elderly patients, with an increased burden of cardiovascular comorbidities and distinctive features compared to young patients. Further investigations are needed in order to better clarify the nosologic criteria, and management in this subset population.
Synthesis and Wear Behaviour Analysis of SiC- and Rice Husk Ash-Based Aluminium Metal Matrix Composites
Authors: Mustafa Sameen , Haider Julfikar , Matteis Paolo , Murtaza Qasim
Published: September 2023

Research efforts seek to develop aluminium alloy composites to enhance the poor tribological performance of aluminium alloy base matrix. In this research, a hybrid metal matrix composite (HMMC) was developed by reinforcing an aluminium alloy (AA8011) with SiC and rice husk ash (RHA) using a stir casting technique. RHA was prepared by the cracking of rice husk, which is abundantly available in the Indian subcontinent. The samples were cast by keeping the amount of RHA constant at 2.5 wt.% and varying the amount of SiC from 0.0 wt.% to 8 wt.%. The samples were machined to manufacture pins for wear tests (at ambient temperature, 100 °C, and 200 °C) and hardness measurement. The microstructures of the cast samples were analysed using an X-ray diffractometer (XRD) and a scanning electron microscope (SEM), along with energy-dispersive X-ray spectroscopy (EDS). It was observed that the composites with greater reinforcement of SiC exhibited improved hardness and wear resistance, but the coefficient of friction increased with the addition of RHA and SiC, and the wear performance deteriorated with an increase in the operating temperature. The contribution of RHA alone to the improvement in wear performance was marginal compared to the pure alloy. It was also confirmed that the reinforced composites could be a better option for automotive applications to replace aluminium alloys.
Comparison of Fungal Genera Isolated from Cucumber Plants and Rhizosphere Soil by Using Various Cultural Media
Authors: Cheng Chong-Yang , Zhang Ming-Yuan , Niu Yong-Chun , Zhang Meng , Geng Yue-Hua , Deng Hui
Published: September 2023

Plant endophytic fungi and rhizosphere soil fungi are often reported as biocontrol agents against plant pathogens or with plant growth promotion potential. Four treatments were performed in field and greenhouse experiments where cucumber plants were inoculated with Trichoderma harzianum and Fusarium oxysporum in 2022. The roots, stems and leaves of cucumber plants and their rhizosphere soil were collected twice individually from the field and greenhouse for isolation of cucumber endophytic and rhizosphere soil fungi. All fungal strains were identified through sequence similarity of the ITS1-5.8s-ITS2 rDNA region. The potato dextrose agar (PDA) media yielded the highest number of genera isolated from cucumber plants, rhizosphere soil and both compared to other media. There were no significant differences among the four media for the isolation of all cucumber endophytic fungi. However, in the roots, the number of endophytic fungi isolated by MRBA was significantly higher than that isolated on malt extract agar (MEA), while in the stems, the number of fungi isolated with PDA was significantly higher than that isolated with Martin’s rose bengal agar medium (MRBA). PDA had significantly higher isolation efficiency for the rhizosphere soil fungi than MRBA. The 28 fungal genera had high isolation efficiency, and the endophytic Trichoderma strains were significantly more isolated by MEA than those of MRBA. It is suggested that PDA can be used as a basic medium, and different cultural media can be considered for specific fungal genera.
Development of Masitinib Derivatives with Enhanced Mpro Ligand Efficiency and Reduced Cytotoxicity
Authors: Menendez Cintia A. , Mohamed Adil , Perez-Lemus Gustavo R. , Weiss Adam M. , Rawe Benjamin W. , Liu Guancen , Crolais Alex E. , Kenna Emma , Byléhn Fabian , Alvarado Walter , Mendels Dan , Rowan Stuart J. , Tay Savaş , de Pablo Juan J.
Published: September 2023

Recently, a high-throughput screen of 1900 clinically used drugs identified masitinib, an orally bioavailable tyrosine kinase inhibitor, as a potential treatment for COVID-19. Masitinib acts as a broad-spectrum inhibitor for human coronaviruses, including SARS-CoV-2 and several of its variants. In this work, we rely on atomistic molecular dynamics simulations with advanced sampling methods to develop a deeper understanding of masitinib’s mechanism of Mpro inhibition. To improve the inhibitory efficiency and to increase the ligand selectivity for the viral target, we determined the minimal portion of the molecule (fragment) that is responsible for most of the interactions that arise within the masitinib-Mpro complex. We found that masitinib forms highly stable and specific H-bond interactions with Mpro through its pyridine and aminothiazole rings. Importantly, the interaction with His163 is a key anchoring point of the inhibitor, and its perturbation leads to ligand unbinding within nanoseconds. Based on these observations, a small library of rationally designed masitinib derivatives (M1–M5) was proposed. Our results show increased inhibitory efficiency and highly reduced cytotoxicity for the M3 and M4 derivatives compared to masitinib.
Potassium Chloride, Sodium Lactate and Sodium Citrate Impaired the Antimicrobial Resistance and Virulence of Pseudomonas aeruginosa NT06 Isolated from Fish
Authors: Tomaś Natalia , Myszka Kamila , Wolko Łukasz
Published: September 2023

Sodium chloride (NaCl) is a commonly used additive in minimally processed fish-based products. The addition of NaCl to fish products and packaging in a modified atmosphere is usually efficient with regard to limiting the occurrence of the aquatic environmental pathogen Pseudomonas aeruginosa. Given the negative effects of excess NaCl in the diet, there is a growing demand to reduce NaCl in food products with safer substituents, but the knowledge of their impact on antibiotic resistant P. aeruginosa is limited. This study aimed to evaluate the physiological and transcriptome characteristics of P. aeruginosa NT06 isolated from fish and to determine the effect of selected concentrations of alternative NaCl compounds (KCl/NaL/NaC) on the P. aeruginosa NT06 virulence phenotype and genotype. In the study, among the isolated microorganisms, P. aeruginosa NT06 showed the highest antibiotic resistance (to ampicillin, ceftriaxone, nalidixic acid, and norfloxacin) and the ability to grow at 4 °C. The Comprehensive Antibiotic Resistance Database (CARD) and the Virulence Factor Database (VFDB) revealed the presence of 24 and 134 gene products assigned to AMR and VF in the P. aeruginosa NT06 transcriptome, respectively. KCl, KCl/NaL and KCl/NaL/NaC inhibited pyocyanin biosynthesis, elastase activity, and protease activity from 40 to 77%. The above virulence phenotypic observations were confirmed via RT–qPCR analyses, which showed that all tested AMR and VF genes were the most downregulated due to KCl/NaL/NaC treatment. In conclusion, this study provides insight into the potential AMR and VF among foodborne P. aeruginosa and the possible impairment of those features by KCl, NaL, and NaC, which exert synergistic effects and can be used in minimally processed fish-based products.
Comparative Performance of Rapid Diagnostics for the Detection of T-2 and HT-2 Toxins in Oats
Authors: Meneely Julie , Greer Brett , Kolawole Oluwatobi , He Qiqi , Elliott Christopher
Published: September 2023

The contamination of oat crops by trichothecene mycotoxins, T-2 and HT-2 is an ongoing threat to our food safety. Within the industry, there are increasing concerns about the continued and growing presence of these mycotoxins occurring in oat crops due to climate change, farming practices and the handling of crops post-harvest. To safeguard human health, monitoring these mycotoxins in foodstuffs is paramount to ensure human exposure is limited. To achieve this, effective testing regimes must be established within the industry, consisting not only of rapid, reliable, and accurate analytical methods but also efficient sampling strategies. Four commercial rapid diagnostic kits were assessed against liquid chromatography coupled to mass spectrometry and included three lateral flow devices and one enzyme-linked immunosorbent assay. One-way ANOVA showed a p-value of 0.45 indicating no significant difference between the methods assessed. Qualitative analysis revealed test kits 1, 2, 3, and 4 showed false negative/false positive rates of 1.1/2.2, 7.6/0, 2.2/0, and 6.5/0 percent, respectively. Test Kit 1, the Neogen Reveal® Q+ MAX for T-2/HT-2 Kit provided the most reliable, accurate and cost-effective results. Furthermore, its ease of use and no requirement for technical skill makes it applicable for on-site testing.
APPLYING THE PRINCIPLE OF INTERDISCIPLINARITY TO EXPAND THE RESEARCH METHODOLOGY OF STUDYING O. DOVZHENKO'S WORKS
Authors:   National Academy of Managerial Staff of Culture and Arts, Poleshuk R.
Published: September 2023

Guided by the principle of interdisciplinarity, the article proposes a methodology for the cultural analysis of O. Dovzhenko's works using the method of ethnographic description. The above-mentioned methodology makes it possible to investigate the issue of the difference between Ukrainian and Russian culture, which is significant nowadays, as well as to determine the direction of the development of the Ukrainian culture in order to create the conditions necessary for bourgeois transformations in society. By applying the method of ethnographic description to the study of Dovzhenko's films, we had the opportunity to find out the philosophical contexts, social relations and cultural practices that are relevant to the Ukrainian culture. In addition, the study highlighted the personal attitude of the great director to the ability of the Ukrainian culture to build a bourgeois-democratic society. The methodological practices of the Lipset-Hall school and the British School of Cultural Studies were involved in the research. This allowed us to conduct culturometry and typology of the Ukrainian culture. In particular, the paper investigated the cultural parameters of collectivism/individualism, masculinity/femininity, long-term/short-term orientation, and power distance. The suggested practices made it possible to determine the type of society built by the Ukrainian culture as triadic, individualistic with a medium-term orientation. The triadic society of Ukraine has a fundamental difference from the dyadic society built by the Russian culture. According to O. Dovzhenko, in the future, the Ukrainian culture would be capable of building a bourgeois-democratic society, based on the state-building theory of multiculturalism and individual liberalism, through the development of law, private property, and institutions for ensuring civil and economic freedoms. In the result of the evolutionary development of the Ukrainian culture, the philosophical contexts, social relations and cultural practices of representatives of the Ukrainian society will certainly change in the direction of increasing masculinity, individualism and reducing the distance of power. Key words: interdisciplinarity, cinematography research methodology, O. Dovzhenko's films, cultural analysis, British School of Cultural Studies, Lipset-Hall School.
ENGLISH CLASSICISM OF THE LATE SEVENTEENTH - EARLY EIGHTEENTH CENTURIES: FROM J. MILTON TO A.-A. SHAFTESBURY
Authors:   Kyiv National I. K. Karpenko-Karyi University of Theatre, Cinema and Television, Ternova M.
Published: September 2023

The article focuses on the special features of the development of English classicism in the late seventeenth and the first half of the eighteenth centuries. This period demonstrates new achievements in the logic of the development of such an important area of humanities as classicism; formed as an independent phenomenon between the late sixteenth to the early eighteenth centuries as an independent, trend it was markedly different from general European tendencies. Since the author of the article believes that the first period in the development of English classicism ended with the publication of “An Essays of Dramatic Poesy” (1668) by J. Dryden, it seems of great relevance to analyze the humaniatic views both in the “Dryden era” and in the early 18th century. The role of theoretical developments by J.Milton and A.-E.Sheftesbury, who outlined a specific stage of humanitarian knowledge in the English lands in general, is recreated through a number of fundamentally new approaches to both the theory of drama and attempts to analyse art and artistic creativity at the intersection of several sciences. This research method, which today can be qualified as a "dialogue of sciences", influenced the new perception of the scientific potential of ethics and psychology by his contemporaries. Today, in the context of the relevance of cultural studies, research within the context of which different humanities “intersect” is, firstly, highly valued as an example of culturological approach, and secondly, is defined by the concepts of “interscientific” or “interdisciplinary”, since there are still terminological differences among specialists in this regard. In addition to all of the above-mentioned facts, A.-A. Shaftesbury began to systematize the scientific research of his predecessors, introducing new names to the community of English classicists. He also studied the problem of the sublime, which the researchers of the time thought to be extremely important, since it was considered as heroic consistent and, accordingly, could influence the deepening of ideas about the tragic and dramatic. The author emphasises the fact of expanding the conceptual and categorical apparatus for the study of aesthetic and artistic issues. Key words. Classicism, Neoplatonism, sensualism, aesthetic and artistic aspect, “Greek tragedy”, “dialogue of sciences”, “artistic genius”, “virtuoso”.
STREAMING BROADCASTS OF STARS ON ONLINE RESOURCES AS A COMPONENT OF PERSONAL BRAND PROMOTION
Authors:   Kyiv National University of Culture and Arts, Shvets I.
Published: September 2023

The proposed research touches on today's current means of Internet marketing for popularizing music content. Considering the features and characteristics of online platforms for the distribution of music, we analyze their effectiveness for promoting a personal brand and a music product without attracting additional resources. The Internet affects not only business processes and information exchange, but also art, including music. In today's conditions, communication between artists and their network subscribers has become integrated into social networks. The growing popularity of the digital music format contributes to the dynamic development of streaming services. Therefore, the study aims to analyze the relationship between social networks and streaming platforms in the process of popularizing music content. The importance of promotion in social networks is emphasized as one of the key factors in the development of a personal brand. Keywords: social media marketing, social media popularity, music industry, music streaming service.
THEATRICAL AND DECORATIVE ART OF TRANSCARPATHIA IN THE SOCIO-CULTURAL SPACE OF UKRAINE IN THE 20TH CENTURY (45-90s)
Authors:   National Academy of Managerial Staff of Culture and Arts, Zaitsev O.
Published: September 2023

The article considers theatrical and decorative art of Transcarpathia in the socio-cultural space of Ukraine of the 20th century (45-90s). The trends of the development and research of theatrical and decorative art of Transcarpathia are determined. The paper describes the cultural processes that influenced the development of theatrical and decorative art of Transcarpathia in the context of the socio-cultural space of Ukraine of the specified period. Research of the theatrical and decorative art of Transcarpathia is an attempt to generalize and introduce this concept into scientific circulation, revealing its genesis and connection with artistic and cultural processes and new concepts of modern visual art in Transcarpathia. To solve the tasks set in the article, the author used cultural, systematic, comparative, analytical and other research methods. The scientific novelty of the research lies in the fact that for the first time in cultural studies an attempt has been made to analyze the theatrical and decorative art of Transcarpathia in the socio-cultural space of Ukraine of the 20th century (45-90s). Keywords: theatrical and decorative art, socio-cultural space of Transcarpathia, performance, stage, costume, artist, theater.
PERFORMANCE FEATURES OF THE «CHERVONA RUTA» FESTIVAL: FOCUS ON THE INHERITANCE OF TRADITIONS
Authors:   Kyiv National University of Culture and Arts, Ilienko O. , Furdychko A. ,   Kyiv National University of Culture and Arts
Published: September 2023

The national character of Ukrainian pop music today is determined by the appeal of folklore at various levels. This way of creating compositions leads to such types of interrelationship of folklore with jazz, pop and rock music, arrangements of folk songs, folk music and citation of materials, creation of original compositions based on folklore, fusion of the national manner of performing non-folklore. Today, songs that are synthesized in ethnic motifs and folklore in a modern setting are popular. But back in the 70s, B. Ivasiuk and the Chervona Ruta vocal and instrumental band were the founders of this approach. So far, the arrangements of folk melodies by the band "Chervona Ruta" have been used by popular rock bands - "Haydamaki", "Mandry", "Perkalaba", "Hutsul calypso", "Kobza original", "Crying", "Down" and others. The modern Ukrainian pop band continues the tradition and modernizes its songs in various interpretations. The paper studies the features of the "Chervon Ruta" festival from 1988 to 2016. The focus is on continuing the traditions of the participants of the ensemble festival of the same name. The practical significance is to highlight the directions of musical creativity of the bands that continue (transform) the traditions of the Chervona Ruta ensemble. Keywords: "Chervona Ruta", festival, Ukrainian music, pop standard.
APPLYING INNOVATIVE ACTIVITY TO INCREASE THE COMPETITIVENESS OF THE EVENT INDUSTRY OF UKRAINE IN THE CONDITIONS OF CRISIS DEVELOPMENT
Authors:   Kyiv National University of Culture and Arts, Korolenko Ye.
Published: September 2023

The research is an attempt to analyze the existence of the event industry in the conditions of a crisis reality with the aim of finding new means of support and transformation of the leisure industry. The coronavirus pandemic and the armed aggression of the Russian Federation had a significant impact on all areas of human life. The sphere of culture and recreation was the first to suffer. However, reorientation and adaptation to the conditions of the new reality will allow not only to maintain the existence of the leisure sector, but also significantly increase the benefit ratio for the broad masses of consumers. Therefore, the search for anti-crisis solutions is one of the key vectors of the organization of the leisure industry in today's conditions. Key words: event management, leisure industry, temporary existence, culture in the conditions of war.
HISTORICAL AND CULTURAL RETROSPECTIVE FORMATION OF FINE ART IN MARIUPOL
Authors:   Mariupol State University, Molokova T.
Published: September 2023

The article attempts to analyze the formation and development of fine art in the city of Mariupol. It provides historical background regarding the activities of artists whose lives and works are connected with Mariupol. The author in particular thoroughly studied the characteristic features of the works by Arkhip Kuindzhi is an artistic symbol of Mariupol, described his creative progress and artistic heritage. In addition, the paper attempts to analyze the works by Oleksandr Mogilevskyi, Viktor Arnautov, Albert Makhotin, Serhiy Barannik, etc. The study gives the characteristics of the fine art of the city in the modern period, describes the creative heritage of the most famous artists of Mariupol in the late 20th century – early 21st century (Halyna Harkina, Volodymyr Miski-Ohlu, Pavlo Ponomarenko, Oksana Pehotska, Oleksandr Bondarenko, etc.). The author highlights specific features of the creative methods and searches of modern Mariupol artists, depicts their educational activities. The article gives considerable attention to the educational activities of art institutions in Mariupol, characterizes the work of the Art School of the City Council in Mariupol, the Art School in Mariupol named after Arkhip Kuindzhi, the ART-Center Institution, the Sova Art Center, describes the activities of the Mariupol-87 creative association, which united avant-garde artists. The research indicates that the fine art is actively developing in Mariupol; it is diverse and rich in terms of subjects and creative methods. Key words: fine art, historical retrospective, painting, watercolor, oil paints, easel painting, landscape, still life, art education, creative method, realism, modernism.
Some issues of improving the network of situational centers of the security and defense sector
Authors:   Institute of Mathematical Machines and Systems Problems of the National Academy of Sciences of Ukraine, Grechaninov V.F.
Published: September 2023

The paper deals with the main issues of creating situational centers. Making decisions in com-plex systems is a very complex problem that can be solved using decision support systems. Solving management tasks at the state level, forecasting, analyzing in conditions of hostilities and a state of emergency, overcoming the consequences of emergency situations are intersec-toral. These tasks are solved through the work of experts and analysts on the technological basis of decision support systems functioning as the part of situational management systems in the form of situational centers. Situational centers of the security and defense sector are designed to make management decisions on a complex, multifunctional governance structure, elements of which are often poorly structured and insufficiently formalized. Input information is incom-plete, ambiguous, sometimes contradictory. Thus, the determination of the functional and or-ganizational principles for the creation and development of situational management systems, based on these principles, is an urgent task. Today, the most important task for government agencies is to improve the efficiency of management activities based on comprehensive moni-toring of the current situation and prompt response to its changes. The complexity and unusual-ness of the tasks facing management structures determine the need for proper scientific, intel-lectual, information and analytical support for their solution. Therefore, summarizing the international experience of creating and using situational centers in management structures, the article proposes a substantiation of the organizational and functional structure and gives recommendations for improving the decision support technology, as well as directions and pre-requisites for creating situational centers for public authorities in the security and defense sec-tor. Approaches to achieving compatibility of their work in a single network are proposed, if necessary, and the modes of their functioning are identified.
Development of the method of stochastic dynamic programming with complete information about the state vector in the problem of information and telecommunication robot optimal control
Authors:   National Technical University of Ukraine ", Alekseeva I.V. ,   Kiev Polytechnic Institute of the Name of Igor Sikorskiy", Lysenko O.I. ,   National Technical University of Ukraine "Kiev Polytechnic Institute of the Name of Igor Sikorskiy", Tachinina O.M. ,   National Aviation University, Novikov V.I. ,   National Technical University of Ukraine "Kiev Polytechnic Institute of the Name of Igor Sikorskiy"
Published: September 2023

The paper is focused on an information and telecommunication robot (ITR) that is a cluster of precision mobile mechanical objects (sensors or multisensors) that perform a common mission concerning either monitoring or protection of the territory or the coordinates of the search ob-jects location.ITRs are equipped with wireless telecommunication systems and high-performance small-sized on-board computers that allow the use of cloud technologies and fog computing. A group of unmanned aerial vehicles (UAVs) that perform a common mission (such as searching for victims of natural disasters) and are equipped with interoperable wireless tele-communications systems can be considered as a flying ITR. Mobile sensor networks (robotic sensor networks and systems) are also considered as a possible technical implementation of ITR. From a theoretical point of view, these control objects can be classified as composite dy-namic systems (CDS). The article also analyzes the notion of trajectories of composite dynam-ical systems that are called branched trajectories in the scientific literature. These trajectories consist of several sections of joint movement of CDS subsystems and some sections of their individual movement to the targets along separate branches of the trajectory. Analysis of the physical content of the phenomena that accompany the process of ITR (and especially of mobile ITR) functioning has shown that such clusters are under accidental influence. Therefore, sto-chastic CDS should be considered as a model of ITR functioning. To solve the problem of opti-mizing the process of stochastic CDS control, there arises a task of developing a method of sto-chastic dynamic programming with complete information about the vector of the ITR state. The article describes a solution to the problem of stochastic composite dynamic system control op-timization, with an arbitrary branching scheme provided that complete information about the state vector is available.
Basic provisions, requirements and initial data for the calculation of spare parts sets.
Authors:   Institute of Mathematical Machines and Systems Problems of the National Academy of Sciences of Ukraine,, Strelnikov V.P. , Strelnikov P.V. ,   Institute of Mathematical Machines and Systems Problems of the National Academy of Sciences of Ukraine,
Published: September 2023

The ability to effectively ensure pre-specified level of reliability of the equipment, while main-taining expenditures at a minimum, is one of the foremost requirements and biggest challenges of our time. One of the key elements of the current research is to determine main characteristics of spare parts, e.g. types of spare parts sets, their respective composition, indicators of suffi-ciency of spare elements in spare parts sets, which allows to define the most effective and cost-saving methods of spare elements inventory management for spare parts sets. There have been analyzed some methods for developing the inventory depending on the purpose of the equip-ment, its maintenance and repair, as well as the requirements for the equipment reliability, in-cluding periodic and continuous stocking, periodic stocking with emergency deliveries and re-plenishment by level. To ensure high operational reliability of electronic equipment, mainte-nance and repair, extending the service life of the equipment, a support system is proposed, which includes diagnostic and repair tools, sets of spare parts, etc. In addition, the paper ad-dresses the design of spare parts while taking into account the criteria of reliability of systems operation such as the level of sufficiency, composition and volume of spare parts, which should ensure the functioning of systems with necessary reliability indicators. The suggested methods for spare parts inventory planning and management are based on the most adequate models of reliability that, as a result, provide a significantly more accurate forecasting of the required amount of spare parts and, consequently, a more efficient equipment spare parts inventory plan-ning. The research suggests the main requirements and necessary input data to guarantee the accuracy of such calculations.
�n the distribution of the maximum of a brownian sheet restricted to a lower-dimensional set
Authors:   National Technical University of Ukraine �Igor Sikorsky Kyiv Polytechnic Institute�,, Kruglova N.V. , Dykhovychnyi O.O. ,   National Technical University of Ukraine �Igor Sikorsky Kyiv Polytechnic Institute�,
Published: September 2023

The paper describes sufficient conditions for determining the distribution of functionals of an -dimensional Brownian sheet (Chentsov field) on a set with the dimension lower than the dimension of the field. The results have been obtained through the generalization of the well-known Doob's Theorem on the identity of the transformation of some Gaussian and Wiener processes in the case of random fields. It is known that the distribution of functionals of a Brownian sheet on the sets with the dimension lower than the dimension of the field and a set of suprema of a piecewise linear curve in particular requires dealing with rather cumbersome integrals that might be hard to estimate. The paper suggests an alternative approach to the problem and considers the probability of suprema of a Brownian sheet being less than a certain drift. The obtained results can significantly simplify the task of determining the distribution of functionals of a Brownian sheet by reducing it to the problem of finding distribution on parallelepipeds with the dimension lower than the dimension of the field. There is also illustrated the validity of the obtained theorem through modeling some Brownian sheets and comparing empirical probabilities with theoretical ones. For the simulations, there have been used the R statistical software. In order to model a Brownian sheet, there has been utilized a special algorithm allowing to model random fields with covariance function of a special form as well as their restrictions on sets of lower dimension (curves, piecewise linear curves). The corresponding R code is provided as well.
ome aspects of automation of normative and legal support of intelligence activity
Authors:   Institute of Information Registration Problems of the National Academy of Sciences of Ukraine, Dodonov O.G. , Putyatin V.G. ,   Institute of Information Registration Problems of the National Academy of Sciences of Ukraine, Germaniuk A.P. ,   Institute of Information Registration Problems of the National Academy of Sciences of Ukraine, Kutcenko S.A. ,   Institute of Information Registration Problems of the National Academy of Sciences of Ukraine
Published: September 2023

Conducting intelligence activities is one of the main directions of ensuring national security of any state. This paper is devoted to some aspects of automation of normative and legal support of intelligence activity. The article considers some issues of ensuring the national security of Ukraine, the role and place of intelligence agencies in its provision; it analyzes recent research and publications on the issues related to the growing importance of intelligence in the modern world. The given paper substantiates the necessity of development of the automated system of normative and legal support of intelligence activity and formation in the structure of Ukrainian intelligence bodies a division of the intelligence activity automated normative and legal support which would be responsible for the centralized conducting of normative and legal information on the basis of uniform classification and coding standards. Intelligence support, as well as the processes of collection, accumulation, processing, storage and display of normative and legal documents concerning organization and performance of intelligence activity, classifiers (directories) of the state level, organizational and administrative documents, documents of regime rules and restrictions on intelligence activity are considered. The main tasks of the automated system of normative and legal support of intelligence activity according to different directions are considered. The article also determines some defined roles of specialists (officials) of the automated regulatory support of intelligence activities, as well as the issues of system architecture and main databases. A generalized organizational and functional structure of the automated system of normative and legal support of intelligence activity, which describes the automated functions of the system, is provided.
Визначення ройових часток метафоричної оптимізації у когнітивних технологіях будівництва
Authors: Горда Олена Володимирівна , Рябчун Юлія Володимирівна
Published: September 2023

Об’єктом дослідження є процедура формування ройових частинок метафоричної оптимізації у когнітивних технологіях будівництва в інтелектуальному інформаційному середовищі. Розглянуто та визначено її особливості та склад, на відміну від звичайної процедури формування системи знань запропоновано і описано підхід до її дослідження. За допомогою таких понять, як завдання будівництва, поле завдань будівництва, інформаційний обʼєкт завдань будівництва, проведено аналіз та запропоновано схему вибору для метафоричної оптимізації у завданнях будівельної індустрії. Одним з найбільш проблемних місць є формування поняття в інтелектуальному середовищі будівництва, визначення можливості та обґрунтування застосування алгоритму ройових частинок метафоричної оптимізації на основі когнітивних технологій для нормалізації понять та їх інтелектуальних особливостей у рамках даної проблематики. В ході дослідження використовувалися методи визначення інформаційної взаємодії інтелектуального середовища з об’єктом та суб’єктом будівництва. Запропоновано визначення напрямів формалізації, отримання та поширення знань у будівництві. Визначено перспективний напрям розв’язання складних завдань оптимізації будівництва — евристика, що з об’єктивною неоднозначністю постановки завдань передбачає рішення щодо вибору із сукупності можливих рішень з урахуванням відношень аналогії, подібності, подоби.
Bayesian data analysis in modeling and forecasting nonlinear nonstationary financial and economic processes
Authors: Trofymchuk Oleksandr , Bidyuk Petro , Prosyankina-Zharova Tetyana , Terentiev Oleksandr
Published: September 2023

The study focuses on some aspects of modeling and forecasting the nonlinear nonstationary processes (NNP) of applying the modern Bayesian methods of data, in particular, generalized linear model (GLM) that are popular in analysis of NNP. All Bayesian techniques of data analysis are very popular today thanks to their flexibility, high quality of results, availability of possibilities for structural and parametric optimization and adaptation to new data and conditions of functioning. The structural and parametric adaptation of Bayesian generalized linear models supposes taking into consideration the following elements: number of equations that are necessary for adequate formal description of the processes under study; availability of nonlinearity and nonstationarity; type of random disturbance — its probability distribution and corresponding parameters; order of model equations, and some other structural elements. Such approach to modeling improves model adequacy and quality of final result of their application. Parameter estimation of the models can be performed by making use of rather wide set of methods, more precisely the following: ordinary LS (OLS), nonlinear LS (NLS), maximum likelihood (ML), the method of additional variable (MAV), and Monte Carlo for Markov Chain (MCMC). The last method is distinguished by universality of application to estimation of linear and nonlinear models. Besides, each of Bayesian approaches to data analysis is well supported by appropriate sets of statistical criteria that make it possible thorough quality analysis of intermediate and final results of computations. Illustrative examples are presented the usage of the Bayesian approach for analysis and forecasting of NNP, in particular, in specialized intellectual decision support system.
DAMAGE CONTROL IN ORTHOPEDICS
Authors:   CHC Kosovska Mitrovica, Department of Orthopedic Surgery and Traumatology, Serbia, Jovanović Saša , Denović Predrag ,   CHC Kosovska Mitrovica, Department of Orthopedic Surgery and Traumatology, Serbia
Published: September 2023

Introduction: DAMAGE CONTROL - in orthopedic surgery and traumatology, it is indicated for fresh fractures, especially for trauma with open bone fractures. In all these fresh fractures, hemodynamic instability of the body occurs. In these cases, a minimally invasive procedure is recommended, which initially aims to temporarily stabilize the fractures and control bleeding Material and methods: In our work, we will present the official literature that deals with the issue of damage control in orthopedics. Discussion: One of the leading causes of death in people under 40 is polytrauma. Fractures of the diaphysis of the tibia, femur, and pelvis are the most common fractures that are stabilized using external fixation. Bilateral fractures of the femoral diaphysis are associated with a poor prognosis in terms of mortality and fat embolism syndrome.Hemodynamically stable patients should always undergo definitive fracture fixation. Any prolonged intervention in hemodynamically unstable patients worsens the favorable outcome. Then the immune response can be triggered and increased, which is identified with the clinical condition “Second trauma”. Therefore, these patients should be immediately subjected to DAMAGE CONTROL with temporary stabilization and then delayed definitive fixation for a period of 5-10 days from damage control, i.e. in the second act. Orthopedic surgeons should be very careful and recognize the triangle of death - acidosis, hypothermia and coagulopathy, which are interconnected and eventually become irreversible and lead to death as the final outcome. Damage control surgery in orthopedics includes three stages: the first stage of treatment involves controlling bleeding, reducing contamination, and achieving temporary fracture fixation. The time in which all this is done should be as short as 1-2 hours. The second phase involves the stabilization of vital parameters in the ICU as well as the reanimation of the child with the prescription of the necessary therapy as well as blood replacement The aim: The aim of our work is to demonstrate the outcome and feasibility of damage control in orthopedic surgery for both adults and children with multiple limb injuries and polytraumatized patients Conclusion: Polytrauma is a condition of the body that requires immediate action and a special approach because the patient’s life is at risk in a high percentage. The principles used to manage patients with multiple injuries including head, lower leg. Early fracture fixation led to earlier mobilization of patients and thus And reduced the percentage of complications, wound infections as well as reducing treatment costs. DAMAGE CONTROL is not only used in traumatized adult patients. It is also necessary to do it in children’s patients.