bluuebunny/crossref_metadata_2025 huggingface dataset:
Patient-Reported Outcome Measures (PROMs) for Two Implant Placement Techniques in Sinus Region (Bone Graft versus Computer-Aided Implant Surgery): A Randomized Prospective Trial
Authors: Almahrous Ghazwan , David-Tchouda Sandra , Sissoko Aboubacar , Rancon Nathalie , Bosson Jean-Luc , Fortin Thomas
Published: April 2020

Purpose: To assess patient-reported outcomes measures (PROMs) for two implant placement techniques in cases of sinus bone atrophy (bone graft surgery (BGS) versus computer-aided implant surgery (CAIS)), after surgery and one year later, and to evaluate the clinical success of both treatments. Methods: Sixty patients with bone atrophy in the posterior maxilla and in need of implant placement were randomly assigned to two groups, and in accordance with the case report form (CRF), 30 were treated with BGS and 30 with CAIS. Immediately after treatment and one year later, PROMs were assessed, and the clinical success of both treatments was evaluated. Results: No significant differences were found between BGS and CAIS with regard to the following: loss of implants (p = 492); patient recommendation (p = 210); duration of surgery (p = 987); pain on the intervention day (p = 512); pain in the week after intervention (p = 299); and complications in the stage of surgery (p = 1.00). Similarly, at one year, no differences were found with regard to the following: pain around implant (p = 481); infection of implants (p = 491); abnormal radiographic imaging (p = 226); occurrence of undesirable events (p = 1.00); loss of one of the implants (p = 1.00); plaque detection (p = 1.00); bleeding on probing (p = 236); and presence of keratinized mucosa (p = 226). However, a significant difference was found among BGS and CAIS with regard to the number of consultations (p = 0001); number of implants placed (p = 033); and treatment difficulty (p = 0369). Significant differences were found for peri-implantitis (p = 0481) and radiology of craterization (p = 020) in clinical examination at the first year. Conclusion: Treatment difficulty and number of consultations were higher for BGS than for CAIS, as well as peri-implantitis and bone craterization at one year, indicating significant differences between the two treatments. However, there were no statistically significant differences between BGS and CAIS regarding the other PROMs, at placement and after one year.
Patient Reported Outcome Measures of Sleep Quality in Fibromyalgia: A COSMIN Systematic Review
Authors: Climent-Sanz Carolina , Marco-Mitjavila Anna , Pastells-Peiró Roland , Valenzuela-Pascual Fran , Blanco-Blanco Joan , Gea-Sánchez Montserrat
Published: April 2020

Poor sleep quality is a common concern and a troublesome symptom among patients suffering from fibromyalgia. The purpose of this review was to identify and describe the available patient reported outcome measures (PROMs) of sleep quality validated in adult people diagnosed with fibromyalgia. The COSMIN and PRISMA recommendations were followed. An electronic systematized search in the electronic databases PubMed, Scopus, CINAHL Plus, PsycINFO, and ISI Web of Science was carried out. Validation studies of PROMs of sleep quality in fibromyalgia published in English or Spanish were included. The selection of the studies was developed through a peer review process through the online software “COVIDENCE”. The quality of the studies was assessed using the COSMIN Risk of Bias checklist. A total of 5 PROMs were found validated in patients with fibromyalgia: (1) Pittsburgh Sleep Quality Index (PSQI), (2) Jenkins Sleep Scale (JSS), (3) Sleep Quality Numeric Rating Scale (SQ-NRS), (4) Medical Outcomes Study-Sleep Scale (MOS-SS), and (5) Fibromyalgia Sleep Diary (FSD). The quality of the evidence was very good and the quality of the results ranged from moderate to high. All the included PROMs, except for the FSD, showed adequate psychometric properties and, therefore, are valid and reliable tools for assessing sleep quality in the context of FM. However, none of the studies analyzed all the psychometric properties of the included PROMs as established in the COSMIN guidelines, highlighting that this is a potential field of research for future investigations.
How Could Peers in Online Health Community Help Improve Health Behavior
Authors: Li Yumei , Yan Xiangbin
Published: April 2020

Human behavior is the largest source of variance in health-related outcomes, and the increasingly popular online health communities (OHC) can be used to promote healthy behavior and outcomes. We explored how the social influence (social integration, descriptive norms and social support) exerted by online social relationships does affect the health behavior of users. Based on an OHC, we considered the effect of three types of social relationships (friendship, mutual support group and competing group) in the OHC. We found that social integration, descriptive norms and social support (information and emotional support) from the OHC had a positive effect on dietary and exercise behavior. Comparing the effects of different social relationships, we found that the stronger social relationship—friendship—had a stronger effect on health behavior than the mutual support group and competing group. Emotional support had a stronger effect on health behavior than informational support. We also found that the effects of social integration and informational support became stronger as membership duration increased, but the effects of the descriptive norms and emotional support became smaller. This study extended the research on health behavior to the online social environment and explored how the social influence exerted by various social relationships in an OHC affected health behavior. The results could be used for guiding users to make use of online social relationships for changing and maintaining healthy behavior, and helping healthcare websites improve their services.
Mitigating the Psychological Impact of COVID-19 on Healthcare Workers: A Digital Learning Package
Authors: Blake Holly , Bermingham Fiona , Johnson Graham , Tabner Andrew
Published: April 2020

The coronavirus pandemic (COVID-19) will undoubtedly have psychological impacts for healthcare workers, which could be sustained; frontline workers will be particularly at risk. Actions are needed to mitigate the impacts of COVID-19 on mental health by protecting and promoting the psychological wellbeing of healthcare workers during and after the outbreak. We developed and evaluated a digital learning package using Agile methodology within the first three weeks of UK outbreak. This e-package includes evidence-based guidance, support and signposting relating to psychological wellbeing for all UK healthcare employees. A three-step rapid development process included public involvement activities (PPIs) (STEP 1), content and technical development with iterative peer review (STEP 2), and delivery and evaluation (STEP 3). The package outlines the actions that team leaders can take to provide psychologically safe spaces for staff, together with guidance on communication and reducing social stigma, peer and family support, signposting others through psychological first aid (PFA), self-care strategies (e.g., rest, work breaks, sleep, shift work, fatigue, healthy lifestyle behaviours), and managing emotions (e.g., moral injury, coping, guilt, grief, fear, anxiety, depression, preventing burnout and psychological trauma). The e-package includes advice from experts in mental wellbeing as well as those with direct pandemic experiences from the frontline, as well as signposting to public mental health guidance. Rapid delivery in STEP 3 was achieved via direct emails through professional networks and social media. Evaluation included assessment of fidelity and implementation qualities. Essential content was identified through PPIs (n = 97) and peer review (n = 10) in STEPS 1 and 2. The most important messages to convey were deemed to be normalisation of psychological responses during a crisis, and encouragement of self-care and help-seeking behaviour. Within 7 days of completion, the package had been accessed 17,633 times, and healthcare providers had confirmed immediate adoption within their health and wellbeing provisions. Evaluation (STEP 3, n = 55) indicated high user satisfaction with content, usability and utility. Assessment of implementation qualities indicated that the package was perceived to be usable, practical, low cost and low burden. Our digital support package on ‘psychological wellbeing for healthcare workers’ is free to use, has been positively evaluated and was highly accessed within one week of release. It is available here: Supplementary Materials. This package was deemed to be appropriate, meaningful and useful for the needs of UK healthcare workers. We recommend provision of this e-package to healthcare workers alongside wider strategies to support their psychological wellbeing during and after the COVID-19 pandemic.
HEADS UP: Design and Methods of a Louisiana State-Funded Surgical and Non-Surgical Weight Loss Program
Authors: Brantley Phillip J. , Guan Win , Brock Ricky , Zhang Dachuan , Hu Gang
Published: April 2020

This paper describes the methodology, design and procedures used in the HEADS UP Project, an observational study to examine the feasibility of a state-funded weight loss program. HEADS UP offered two weight loss approaches: bariatric surgery or a non-surgical intervention composed of medical management, a low-calorie liquid diet and lifestyle change promotion. Participants were recruited through a multi-stage screening process, in-person interviews, and an initial low-calorie diet program. Eligible participants were entered into a lottery system, with 100 participants selected for the surgical group and 200 selected for the non-surgical group annually for five years. Anthropometric, clinical, and psychosocial assessments were completed at baseline and follow-ups. More than 6800 individuals completed the initial web screening. Screening procedures yielded 1412 participants (490 surgical and 922 non-surgical). Approximately 84% of the total participant population were female and 38% were Black. Participants had an average body mass index of 47.9 and 43 kg/m2 in the surgical and non-surgical groups, respectively. Recruitment and enrollment results of the HEADS UP study demonstrated significant interest in both the surgical and non-surgical treatment programs for obesity. These results support the feasibility of providing a state-funded weight loss program within a healthcare setting.
Factors Associated with Metabolic Syndrome Among Middle-Aged Women in Their 50s: Based on National Health Screening Data
Authors: Kim HyungSeon , Cho YeonHee
Published: April 2020

This study aimed to identify the risk factors associated with metabolic syndrome among middle-aged women in their 50s to provide a strategy for managing the metabolic syndrome of those whose prevalence is rapidly increasing. Secondary data from the 2012 Korean National Health Insurance Service Medical check-up cohort database were analyzed. Participants included 36,582 middle-aged women in their 50s from the cohort who received a general medical check-up. The risk factors were estimated using logistic regression analysis. Metabolic syndrome was identified in 14.6% of the surveyed persons among middle-aged women in their 50s. Working women, low household income levels, country residents, high body mass index (BMI), total cholesterol of over 240 mg/dL, non-drinker, non-exerciser, history of diabetes or hypertension, and family history of diabetes were associated with increased risk of metabolic syndrome. It is necessary to prepare a strategy to increase access to health care services so that socioeconomic vulnerability does not lead to negative health behavior such as obesity and lack of physical activity. In particular, we recommend active interventions at workplaces for the working women who have a higher risk of metabolic syndrome.
Evidence Relating to Environmental Noise Exposure and Annoyance, Sleep Disturbance, Cardio-Vascular and Metabolic Health Outcomes in the Context of IGCB (N): A Scoping Review of New Evidence
Authors: van Kamp Irene , Simon Sendrick , Notley Hilary , Baliatsas Christos , van Kempen Elise
Published: April 2020

WHO published the Environmental Noise Guidelines for the European Region in 2018, based on seven systematic reviews including studies published between 2000 and 2014. Since then, new studies were published. At the request of the UK Department for Environment, Food and Rural Affairs (DEFRA), a review on annoyance, sleep disturbance, cardiovascular and metabolic effects in relation to environmental noise was prepared. The aim was to advise the Interdepartmental Group on Costs and Benefits Noise Subject Group (IGCB(N)) whether this new evidence warrants an update of their recommendations. Four databases for observational studies were screened and data were extracted on design, type and measurements of exposures and outcomes and confounders and their associations. The quality of the studies was indirectly assessed for cardiovascular and metabolic effects by only including studies with a case control or cohort design. For studies on annoyance and sleep disturbance, the risk of bias was expressed in exposure misclassification, selective participation and confounding. The update yielded 87 papers, pertaining to 108 new studies of which 40 new studies were on annoyance, 42 on sleep disturbance and 26 concerning cardiovascular and metabolic effects. The number, size and quality of the new studies suggest new meta-analyses could be undertaken over the sources and effects included in the WHO reviews.
Relative Risk of High-Danger Industries in China from 2004 to 2016
Authors: Zhang Lu , Luo Yun , Xu Ming , Wang Guantao , Liang Wei , Xiang Yang
Published: April 2020

Accidents in high-danger industries in China occur frequently and cause loss of life, injuries, and economic loss. One of the most important reasons causing severe safety situations is the lack of knowledge on macro industry risk in the practice and academic field in China. In order to solve this problem, the method to calculate group risk and individual risk, concerning risk aversion, is discussed, selected, and improved. The group risks and individual risks of five high-danger industries from 2004 to 2016 are calculated. Relative risk indices between five high-danger industries during the 11th and 12th Five-Year Guideline for National Economic and Social Development (FYP) are determined. The results show that there are some differences between group risk and individual risk of high-danger industries. The reasons for differences and the connections with published interventions are discussed. Through discussion, two different ways to reduce group risk and individual risk are identified, which could help supervisors inspect the actual effectiveness of safety policies, measures, and interventions and choose a better way to reduce risk and ensure work safety in industries.
Assessing Changes in Ecosystem Service Values in Response to Land Cover Dynamics in Jiangxi Province, China
Authors: Zhang Xinmin , Xie Hualin , Shi Jiaying , Lv Tiangui , Zhou Caihua , Liu Wangda
Published: April 2020

This paper examines the ecosystem service values of Jiangxi province, China using the benefit transfer approach. The land cover dynamics results show that cropland and forest are the main land cover types in Jiangxi province. Urban land drastically increased after 2000, expanding from 846.54 km2 in 2000 to 2317.48 km2 in 2015. Forest and water obviously decreased across the study periods. Consequently, the total ecosystem service values decreased from 37.91 × 1010 Yuan in 1995 to 35.27 × 1010 Yuan in 2015. The values showed a declining trend, especially during the 1995–2000 period. The largest declines in ecosystem service values were caused by decreases in forest and water cover. Regulating services experienced the largest declines in ecosystem services value. Moreover, water supply showed the largest decline in ecosystem service value between 1995 and 2015. Not surprisingly, food production increased in the whole period, especially in the 1995–2000 period. Forest and cropland played the most important roles in the total ecosystem service values of Jiangxi province. We then discussed the relationship among ecosystem services based on the ecosystem service trade-off degree. The results show that the dominant relationship among ecosystem services in Jiangxi province was synergy; thus synergy mostly occurred in all ecosystem services except for food production from 1995 to 2015. However, during the 1995–2000 period, trade-offs mainly existed in both food production and waste treatment. The proportion of synergy greatly increased in the 2000–2015 period, and the synergistic relationship between waste treatment and other ecosystem services increased. However, the trade-off relationship between food production and other ecosystem services still has not improved, which should be concerned in the future. Changes in the percentage share of cropland showed a declining trend; thus, the potential risk of cropland loss should be monitored.
A Preliminary Evaluation of the Public Risk Perception Related to the COVID-19 Health Emergency in Italy
Authors: Motta Zanin Giulia , Gentile Eleonora , Parisi Alessandro , Spasiano Danilo
Published: April 2020

Governments faced with the spread of COVID-19 pandemic are adopting strict and severe mitigation measures to influence people’s behaviors. Public perception of health risk plays a key role in the adoption of these actions, in people’s feelings, and in their daily habits. To support decision makers from international to local levels to face with future sanitary emergencies, this study aims at investigating Italian public perceptions of health risk. To this purpose, a questionnaire was designed and administered within the period of Italian COVID-19 lockdown and quarantine to almost 9000 citizens in Italy and abroad. The obtained results highlight a significative influence that mass media play on both the level of knowledge and the feelings of the respondents. The findings also point out future variations of some perceived behaviors consequent to the COVID-19 outbreak.
Impact of Combined Theory-Based Intervention on Psychological Effects and Physical Activity among Chinese Adolescents
Authors: Zhang Yao , Yin Yi , Liu Jianxiu , Yang Ming , Liu Zeshi , Ma Xindong
Published: April 2020

Purpose: The current study was intended to assess the effect of a facilitated behavioral intervention based on the extended theory of planned behavior (TPB) on psychological constructs and physical activity among adolescents over a period of eight weeks. Methods: Students (n = 51, 12 ± 0.3 years of age) in the seventh grade at a junior middle school in China were randomly assigned to two groups: the intervention group (n = 24) and the control group (n = 27). Both groups were pre- and post-tested with the related psychological constructs of the extended TPB, along with behavioral measures of the Physical Activity Scale and ActiGraph accelerometer (model wGT3X-BT). The intervention group took part in 45 min classes once per week for 8 weeks, including five indoor theoretical courses and three outdoor basketball matches. The control group was not required to make any change to their normal school day. Also, 2 × 2 repeated measures analysis of variance (ANOVA) was conducted to compare the differences between the two groups, and then t-test was employed to compare the independent and paired differences. Results: Significant increases in pre–post subjective norms (SN) (p = 0.041, Cohen’s d = 0.62), perceived behavior control (PBC) (p = 0.023, Cohen’s d = 0.72), exercise intention (EI) (p = 0.043, Cohen’s d = 0.61), and self-efficacy (SE) (p = 0.035, Cohen’s d = 1.36) were observed in the intervention group. In addition, participants in the intervention group increased their exercise frequency (p < 0.001, Cohen’s d = 1.25) and intensity (p = 0.028, Cohen’s d = 0.68), especially their time spent on light intensity physical activity (light-PA%; p = 0.031, Cohen’s d = 0.68), and their percentage of sedentary time (SB%) was also reduced (from 68% ± 10% to 58% ± 7%, p < 0.001, Cohen’s d = 1.17). Furthermore, the intervention group showed significantly better performance in PBC (p = 0.032, Cohen’s d = 0.62), EI (p < 0.001, Cohen’s d = 1.32), SE (p < 0.001, Cohen’s d = 1.15), SB% (p < 0.001, Cohen’s d = 1.22), light-PA% (p < 0.001, Cohen’s d = 1.12), and total physical activity (TPA) (p = 0.015, Cohen’s d = 0.72) compared to the control group at the post-test. No significant pre post differences were observed for any psychological or behavioral variables in the control group, except for exercise frequency, but the values were still lower than those in the intervention group after the 8-week intervention (3.70 ± 0.72 versus 3.92 ± 0.83). Conclusion: The combined theory-based intervention was effective at improving psychological constructs and physical activity among seventh-grade adolescents in 8 weeks.
Tunnelled Haemodialysis Catheter Removal: An Underappreciated Problem, Not Always Simple and Safe
Authors: Porazko Tomasz , Hobot Jacek , Ziembik Zbigniew , Klinger Marian
Published: April 2020

Background: Optimal care of patients treated with a central tunneled catheter (CTC) as vascular access for hemodialysis requires a number of procedures. One of them is CTC removal, usually carried out using mostly the cut-down method (CDM) and the traction method (TM). The procedure seems to be simple and safe; however, occasionally, serious complications may occur. To eliminate the risk of such events, we have introduced a modified cut-down method (MCDM). Methods: The study included the analysis of retrospective results of 143 CTC removal procedures, 76 of which were performed using the standard cut-down method (CDM), and in 67 cases, the modified cut-down method (MCDM) was applied. Results: As minor side effects occurred in patients treated with both methods with comparable frequency, serious complications were observed only in the CDM patients group. Conclusions: In our opinion, the new MCDM procedure is the simplest and safest method of CTC removal.
Determining the Optimal Outcome Measures for Studying the Social Determinants of Health
Authors: Muennig Peter , McEwen Bruce , Belsky Daniel W. , Noble Kimberly G. , Riccio James , Manly Jennifer
Published: April 2020

Americans have significantly poorer health outcomes and shorter longevity than citizens of other industrialized nations. Poverty is a major driver of these poor health outcomes in the United States. Innovative anti-poverty policies may help reduce economic malaise thereby increasing the health and longevity of the most vulnerable Americans. However, there is no consensus framework for studying the health impacts of anti-poverty social policies. In this paper, we describe a case study in which leading global experts systematically: (1) developed a conceptual model that outlines the potential pathways through which a social policy influences health, (2) fits outcome measures to this conceptual model, and (3) estimates an optimal time frame for collection of the selected outcome measures. This systematic process, called the Delphi method, has the potential to produce estimates more quickly and with less bias than might be achieved through expert panel discussions alone. Our case study is a multi-component randomized-controlled trial (RCT) of a workforce policy called MyGoals for Healthy Aging.
Association between Sleep Quality and Duration and Periodontal Disease among University Students: A Cross-Sectional Study
Authors: Islam Md Monirul , Ekuni Daisuke , Toyama Naoki , Taniguchi-Tabata Ayano , Kataoka Kota , Uchida-Fukuhara Yoko , Fukuhara Daiki , Saho Hikari , Sawada Nanami , Nakashima Yukiho , Iwasaki Yoshiaki , Morita Manabu
Published: April 2020

The purpose of this cross-sectional study was to investigate the association between sleep quality and duration, and periodontal disease among a group of young Japanese university students. First-year students (n = 1934) at Okayama University who voluntarily underwent oral health examinations were included in the analysis. Sleep quality and duration were assessed by the Japanese version of the Pittsburgh Sleep Quality Index. Dentists examined Oral Hygiene Index-Simplified (OHI-S), probing pocket depth (PPD), and percentage of sites with bleeding on probing (BOP). Periodontal disease was defined as presence of PPD ≥ 4 mm and BOP ≥ 30%. Overall, 283 (14.6%) students had periodontal disease. Poor sleep quality was observed among 372 (19.2%) students. Mean (± standard deviation) sleep duration was 7.1 ± 1.1 (hours/night). In the logistic regression analysis, periodontal disease was significantly associated with OHI-S (odds ratio [OR]: 2.30, 95% confident interval [CI]: 1.83–2.90; p < 0.001), but not sleep quality (OR: 1.09, 95% CI: 0.79–1.53; p = 0.577) or sleep duration (OR: 0.98, CI: 0.87–1.10; p = 0.717). In conclusion, sleep quality and duration were not associated with periodontal disease among this group of young Japanese university students.
Effectiveness of the Reasoning and Rehabilitation V2 Programme for Improving Personal and Social Skills in Spanish Adolescent Students
Authors: Sánchez-SanSegundo Miriam , Ferrer-Cascales Rosario , Albaladejo-Blazquez Natalia , Alarcó-Rosales Raquel , Bowes Nicola , Ruiz-Robledillo Nicolás
Published: April 2020

Significant progress has been made in developing intervention programmes for adolescents at high risk of delinquency, school failure and emotional problems. The most effective programmes incorporate behavioural and skills training aimed at changing attitudes and promoting psychosocial and emotional skills in adolescents. This study examined the effectiveness of a school-based intervention programme based on the Reasoning and Rehabilitation V2 (R&R2). R&R2 is a cognitive behavioural programme developed using psychological theories about the aetiology of delinquency, as well as the cognitive, behavioural and socioemotional deficits in high-risk youth populations. A sample of 142 students (aged 13–17 years old) who were attending alternative education provision in Spain were randomly assigned to two experimental conditions (68 experimental group, 74 control group). The results showed that the R&R2 improved participants’ self-esteem, social skills, empathy and rational problem-solving with a medium–large effect size (η2 = 0.08 to 0.26). The effects of the programme were significant after controlling for age and the pre-test scores in baseline. These findings confirm the effectiveness of the Reasoning and Rehabilitation V2 programme in Spanish adolescent students and offer additional evidence regarding the implementation of the R&R2 programme in both alternative educational and mainstream school settings.
Initial Validation of the Diabetes and Breastfeeding Management Questionnaire (DBM-Q)
Authors: Linden Karolina , Berg Marie , Sparud-Lundin Carina , Adolfsson Annsofie , Melin Jeanette
Published: April 2020

Women with pre-gestational diabetes face additional challenges after birth as they struggle with breastfeeding and managing unpredictable blood glucose levels. The aim of this study is to validate the Diabetes and Breastfeeding Management Questionnaire (DBM-Q). In total, 142 mothers with type 1 diabetes mellitus answered the questionnaire, which initially consisted of 11 items. The response rate was 82.5% (n = 128) at two months, and 88.4% (n = 137) at six months postpartum. The measurement properties of the Diabetes and Breastfeeding Management Questionnaire were tested according to the Rasch measurement theory (RMT). One item showed both disordered thresholds and several model misfits and was removed. Two items showed disordered thresholds which were resolved by collapsing response categories. This resulted in a 10-item questionnaire with all the fit residuals within the range of +2.5, minor significant differential item functioning, well-targeted items and a person separation index of 0.73. Evaluating the DBM-Q according to the RMT is a strength, as it evaluates data against strict measurement criteria. This study provides an initial validation of the questionnaire. The DBM-Q shows good measurement properties for measuring diabetes and breastfeeding management postpartum in women with pre-gestational diabetes. Further studies are needed to identify cutoffs for when professional support is needed.
Methodological Analysis of the Effect of an Anti-Bullying Programme in Secondary Education through Communicative Competence: A Pre-Test–Post-Test Study with a Control-Experimental Group
Authors: González-Alonso Fernando , Guillén-Gámez Francisco D. , de Castro-Hernández Rosa Mᵃ
Published: April 2020

The promotion of communicative competence in students play a key role in schools for the purpose of improving social, emotional and coexistence relationships in Secondary Education students. The development of said competence can represent a great strategy to improve conflicts in the classroom, notably bullying. We used a quasi-experimental pre-test and post-test control group design with a sample of 55 students from the city of Salamanca (Spain) to analyse the level of conflict and their perceptions about bullying during the 2017–2018 academic year. The anti-bullying programme called the Improvement of Coexistence and Communicative Competence (ICCC) programme used is. The behaviour of students based on their level of coexistence with the group of classmates was measured by the INSEBULL instrument (Bullying Assessment Instrument), which added one more dimension of own elaboration. The results showed that, even though the significant levels of conflict, they decreased substantially once the ICCC programme was applied. Furthermore, we found differences between the control and experimental groups which underlined the effectiveness of the program. Regarding gender, no differences were found in the experimental group. This study shows that the development of communicative competence in students has a significant impact on their level of coexistence with other classmates, although the results suggested the need for longitudinal implementation of the programme in order to improve school coexistence and social skills of students from the early stages of education.
The Unrealised Potential for Predicting Pregnancy Complications in Women with Gestational Diabetes: A Systematic Review and Critical Appraisal
Authors: Cooray Shamil D. , Wijeyaratne Lihini A. , Soldatos Georgia , Allotey John , Boyle Jacqueline A. , Teede Helena J.
Published: April 2020

Gestational diabetes (GDM) increases the risk of pregnancy complications. However, these risks are not the same for all affected women and may be mediated by inter-related factors including ethnicity, body mass index and gestational weight gain. This study was conducted to identify, compare, and critically appraise prognostic prediction models for pregnancy complications in women with gestational diabetes (GDM). A systematic review of prognostic prediction models for pregnancy complications in women with GDM was conducted. Critical appraisal was conducted using the prediction model risk of bias assessment tool (PROBAST). Five prediction modelling studies were identified, from which ten prognostic models primarily intended to predict pregnancy complications related to GDM were developed. While the composition of the pregnancy complications predicted varied, the delivery of a large-for-gestational age neonate was the subject of prediction in four studies, either alone or as a component of a composite outcome. Glycaemic measures and body mass index were selected as predictors in four studies. Model evaluation was limited to internal validation in four studies and not reported in the fifth. Performance was inadequately reported with no useful measures of calibration nor formal evaluation of clinical usefulness. Critical appraisal using PROBAST revealed that all studies were subject to a high risk of bias overall driven by methodologic limitations in statistical analysis. This review demonstrates the potential for prediction models to provide an individualised absolute risk of pregnancy complications for women affected by GDM. However, at present, a lack of external validation and high risk of bias limit clinical application. Future model development and validation should utilise the latest methodological advances in prediction modelling to achieve the evolution required to create a useful clinical tool. Such a tool may enhance clinical decision-making and support a risk-stratified approach to the management of GDM. Systematic review registration: PROSPERO CRD42019115223.
Sensor-Aided EMF Exposure Assessments in an Urban Environment Using Artificial Neural Networks
Authors: Wang Shanshan , Wiart Joe
Published: April 2020

This paper studies the time and space mapping of the electromagnetic field (EMF) exposure induced by cellular base station antennas (BSA) using artificial neural networks (ANN). The reconstructed EMF exposure map (EEM) in urban environment is obtained by using data from EMF sensor networks, drive testing and information accessible in a public database, e.g., locations and orientations of BSA. The performance of EEM is compared with Exposure Reference Map (ERM) based on simulations, in which parametric path loss models are used to reflect the complexity of urban cities. Then, a new hybrid ANN, which has the advantage of sorting and utilizing inputs from simulations efficiently, is proposed. Using both hybrid ANN and conventional regression ANN, the EEM is reconstructed and compared to the ERM first by the reconstruction approach considering only EMF exposure assessed from sensor networks, where the required number of sensors towards good reconstruction is explored; then, a new reconstruction approach using the sensors information combined with EMF along few streets from drive testing. Both reconstruction approaches use simulations to mimic measurements. The influence of city architecture on EMF exposure reconstruction is analyzed and the addition of noise is considered to test the robustness of ANN as well.
Turbidity in Combined Sewer Sewage: An Identification of Stormwater Detention Tanks
Authors: Liu Yang , Hou Liangang , Bian Wei , Zhou Banglei , Liang Dongbo , Li Jun
Published: April 2020

Combined sewer overflow remains a major threat to surface water quality. A stormwater detention tank is an effective facility to control combined sewer overflow. In this study, a new method for the selective collection of combined sewer sewage during wet weather based on real-time turbidity control is established to reduce the load of pollutants entering a river using a stormwater detention tank with a limited volume. There was a good correlation found between turbidity and the concentrations of total suspended solids (TSS) (R2 = 0.864, p < 0.05), total phosphorus (TP) (R2 = 0.661, p < 0.01), and chemical oxygen demand (COD) (R2 = 0.619, p < 0.01). This study shows that turbidity can be used to indicate the concentration of TSS, TP, and COD in the sewage of the combined sewer systems in wet weather. Based on the adopted first flush detection approach, total nitrogen (TN) and TP showed the first flush effect, whereas the first flush effect of TSS and COD was not obvious. The results show that it is impossible to effectively control combined sewer overflow by only treating the initial rainwater.
The Influence of the Privatization Process on Accident Rates in the Forestry Sector in Poland
Authors: Grzywiński Witold , Skonieczna Joanna , Jelonek Tomasz , Tomczak Arkadiusz
Published: April 2020

The aim of this paper is to analyze the changes in accident rates resulting from the privatization of forest operations. Data from the years 1990–2017 were obtained from the Statistical Forestry Yearbooks issued by Statistics Poland, and were analyzed for two periods: the time of intensive privatization (1991–2002) and the post-privatization period (2003–2017). The data from 1990 were treated as a benchmark. There were 14,626 accidents in total, of which 236 (1.61%) were fatal. The non-fatal accident rate in the whole forestry industry showed a decreasing trend in the study period (t = 2.27, p < 0.05). In the case of the fatal accident rate we can observe an upward trend; in the period of intensive privatization the average annual fatality rate was 0.11, and after privatization it was 0.18 (t = −2.68, p < 0.05). In both periods the fatality rate was twice as high in the private forestry sector as in the public sector. The number of working days lost declined in the public sector and increased in the private sector. An accident in the private sector resulted in 20 days’ longer absence than one in the public sector. The study confirms that despite economic transition, accident rates in Polish forestry remain a serious issue. The main problem to be addressed is the increase in the fatal accident rate, especially in the private sector.
Children Born with Congenital Heart Defects and Growth Restriction at Birth: A Systematic Review and Meta-Analysis
Authors: Ghanchi Ali , Derridj Neil , Bonnet Damien , Bertille Nathalie , Salomon Laurent J. , Khoshnood Babak
Published: April 2020

Newborns with congenital heart defects tend to have a higher risk of growth restriction, which can be an independent risk factor for adverse outcomes. To date, a systematic review of the relation between congenital heart defects (CHD) and growth restriction at birth, most commonly estimated by its imperfect proxy small for gestational age (SGA), has not been conducted. Objective: To conduct a systematic review and meta-analysis to estimate the proportion of children born with CHD that are small for gestational age (SGA). Methods: The search was carried out from inception until 31 March 2019 on Pubmed and Embase databases. Studies were screened and selected by two independent reviewers who used a predetermined data extraction form to obtain data from studies. Bias was assessed using the Critical Appraisal Skills Programme (CASP) checklist. The database search identified 1783 potentially relevant publications, of which 38 studies were found to be relevant to the study question. A total of 18 studies contained sufficient data for a meta-analysis, which was done using a random effects model. Results: The pooled proportion of SGA in all CHD was 20% (95% CI 16%–24%) and 14% (95% CI 13%–16%) for isolated CHD. Proportion of SGA varied across different CHD ranging from 30% (95% CI 24%–37%) for Tetralogy of Fallot to 12% (95% CI 7%–18%) for isolated atrial septal defect. The majority of studies included in the meta-analysis were population-based studies published after 2010. Conclusion: The overall proportion of SGA in all CHD was 2-fold higher whereas for isolated CHD, 1.4-fold higher than the expected proportion in the general population. Although few studies have looked at SGA for different subtypes of CHD, the observed variability of SGA by subtypes suggests that growth restriction at birth in CHD may be due to different pathophysiological mechanisms.
Trait Emotional Intelligence and School Burnout: The Mediating Role of Resilience and Academic Anxiety in High School
Authors: Fiorilli Caterina , Farina Eleonora , Buonomo Ilaria , Costa Sebastiano , Romano Luciano , Larcan Rosalba , Petrides Konstantinos V.
Published: April 2020

The main aim of the current study was to investigate the role of trait emotional intelligence (TEI) in preventing students’ school burnout directly and indirectly via anxiety and academic resilience. The data were derived from a sample of 1235 high school students (962 females and 273 males), ranging in age between 13 and 17 years (mean = 15.46; stand deviation = 1.22). Structural equation modelling revealed a strong indirect effect of TEI on school burnout, mediated via anxiety and resilience. Overall, students with high TEI were less likely to experience school anxiety and more likely to exhibit resilience which, in turn, reduced school burnout risk. Findings are discussed with reference to the wider role of TEI in educational contexts and highlight the need and potential for scientifically driven interventions to enhance emotional adjustment at school and in life, more generally.
The Influence of Self-Concept on Clinical Decision-Making in Nurses and Nursing Students: A Cross-Sectional Study
Authors: Farčić Nikolina , Barać Ivana , Lovrić Robert , Pačarić Stana , Gvozdanović Zvjezdana , Ilakovac Vesna
Published: April 2020

The aim of this study is to examine the influence of nurses’ self-concept (NSC) on clinical decision-making (CDM) among nursing students and hospital nurses. A further aim is to examine whether there is a difference in CDM and NSC between hospital nurses with various levels of experience and nursing students. A cross-sectional study was conducted during 2018 in the Faculty of Dental Medicine and Health and the University Hospital Center, in Osijek, Croatia, EU. The respondents consisted of 568 hospital nurses, and 129 BSc nursing students. Data were collected with the clinical decision-making in nursing scale (CDMNS) and the nurses’ self-concept questionnaire (NSCQ). There was no correlation between CDM and NSC in either students or hospital nurses. Hospital nurses generally had significantly higher scores in CDM than nursing students. On the other hand, students had a significantly higher total NSC level. The results of this study suggest that experience has a positive impact on nurses’ CDM skills. The high NSC estimated by students enables them to easily take up their clinical roles and approach the patient in a holistic manner, which is an attitude that gradually develops during studies and with clinical experience.
Levels of Octachlorostyrene in Mothers’ Milk and Potential Exposure Among Infants in Sendai City, Japan 2012
Authors: Soleman Sani Rachman , Fujitani Tomoko , Fujii Yukiko , Harada Kouji H.
Published: April 2020

Persistent organic pollutants can accumulate inside the human body, including in mothers’ milk, which may affect infant development. This cross-sectional study aimed to examine selected persistent organic pollutants in the milk of 100 mothers in Sendai city, Miyagi Prefecture, Japan. We used gas-chromatography-electron capture negative chemical ionization-mass spectrometry to check for octachlorostyrene, dechlorane (Dec) plus, Dec 602, Dec 603, and Dec 604. Octachlorostyrene was detected in 86 samples at more than the method detection limit (84 pg g-lipid−1) but no dechloranes were above the method detection limit (1 ng mL−1 for dechlorane plus, Dec 602, and Dec 603; 20 ng mL−1 for Dec 604). The mean octachlorostyrene concentration was 461 pg g-lipid−1, the median was 337 pg g-lipid−1, and the standard deviation 450 pg g-lipid−1. No baseline characteristics were associated with octachlorostyrene level except for mother’s occupation (stay-at-home mother, 353 ± 327 pg g-lipid−1; others, 531 ± 509 pg g-lipid−1). Octachlorostyrene was also significantly negatively correlated with lipid content (r = −0.35, p = 0.0004). However, the maximum intake of octachlorostyrene among infants in this study (3.5 ng/kg/day) was under the acceptable daily intake (30 ng/kg/day, derived from 12−month study in rats), and is therefore unlikely to pose a health risk.
Psychiatric Disorders and lncRNAs: A Synaptic Match
Authors: Rusconi Francesco , Battaglioli Elena , Venturin Marco
Published: April 2020

Psychiatric disorders represent a heterogeneous class of multifactorial mental diseases whose origin entails a pathogenic integration of genetic and environmental influences. Incidence of these pathologies is dangerously high, as more than 20% of the Western population is affected. Despite the diverse origins of specific molecular dysfunctions, these pathologies entail disruption of fine synaptic regulation, which is fundamental to behavioral adaptation to the environment. The synapses, as functional units of cognition, represent major evolutionary targets. Consistently, fine synaptic tuning occurs at several levels, involving a novel class of molecular regulators known as long non-coding RNAs (lncRNAs). Non-coding RNAs operate mainly in mammals as epigenetic modifiers and enhancers of proteome diversity. The prominent evolutionary expansion of the gene number of lncRNAs in mammals, particularly in primates and humans, and their preferential neuronal expression does represent a driving force that enhanced the layering of synaptic control mechanisms. In the last few years, remarkable alterations of the expression of lncRNAs have been reported in psychiatric conditions such as schizophrenia, autism, and depression, suggesting unprecedented mechanistic insights into disruption of fine synaptic tuning underlying severe behavioral manifestations of psychosis. In this review, we integrate literature data from rodent pathological models and human evidence that proposes the biology of lncRNAs as a promising field of neuropsychiatric investigation.
The Impact of Spaceflight and Simulated Microgravity on Cell Adhesion
Authors: Lin Xiao , Zhang Kewen , Wei Daixu , Tian Ye , Gao Yongguang , Chen Zhihao , Qian Airong
Published: April 2020

Microgravity induces a number of significant physiological changes in the cardiovascular, nervous, immune systems, as well as the bone tissue of astronauts. Changes in cell adhesion properties are one aspect affected during long-term spaceflights in mammalian cells. Cellular adhesion behaviors can be divided into cell–cell and cell–matrix adhesion. These behaviors trigger cell–cell recognition, conjugation, migration, cytoskeletal rearrangement, and signal transduction. Cellular adhesion molecule (CAM) is a general term for macromolecules that mediate the contact and binding between cells or between cells and the extracellular matrix (ECM). In this review, we summarize the four major classes of adhesion molecules that regulate cell adhesion, including integrins, immunoglobulin superfamily (Ig-SF), cadherins, and selectin. Moreover, we discuss the effects of spaceflight and simulated microgravity on the adhesion of endothelial cells, immune cells, tumor cells, stem cells, osteoblasts, muscle cells, and other types of cells. Further studies on the effects of microgravity on cell adhesion and the corresponding physiological behaviors may help increase the safety and improve the health of astronauts in space.
Cracking the Monoubiquitin Code of Genetic Diseases
Authors: Sewduth Raj Nayan , Baietti Maria Francesca , Sablina Anna A.
Published: April 2020

Ubiquitination is a versatile and dynamic post-translational modification in which single ubiquitin molecules or polyubiquitin chains are attached to target proteins, giving rise to mono- or poly-ubiquitination, respectively. The majority of research in the ubiquitin field focused on degradative polyubiquitination, whereas more recent studies uncovered the role of single ubiquitin modification in important physiological processes. Monoubiquitination can modulate the stability, subcellular localization, binding properties, and activity of the target proteins. Understanding the function of monoubiquitination in normal physiology and pathology has important therapeutic implications, as alterations in the monoubiquitin pathway are found in a broad range of genetic diseases. This review highlights a link between monoubiquitin signaling and the pathogenesis of genetic disorders.