bluuebunny/crossref_metadata_2025 huggingface dataset:
Triagem neonatal e terapia gênica na atrofia muscular espinhal: uma revisão integrativa
Authors: Gonçalves Ana Carolina Rodrigues , Oliveira Carla Resende Vaz , Barbosa Laíssa de Oliveira Fernandes , Reis Bruno Cezario Costa
Published: March 2022

Objetivo: Analisar o impacto da triagem neonatal e terapia gênica no prognóstico da atrofia muscular espinhal. Métodos: A abordagem metodológica se propõe a um compilado de pesquisa bibliográfica de abordagem qualitativa e caráter descritivo através de uma revisão integrativa de literatura nas bases de dados National Libary of Medicine, Biblioteca Virtual em Saúde e Cochrane Database of Systematic Reviews. Os descritores utilizados foram “muscular atrophy spinal”, “spinal muscular atrofies of childhood” e “genetic therapy”. Os critérios de inclusão foram artigos de jornal article, clinical trial, ensaios clínicos randomizados ou não randomizados, estudos de caso-controle, estudo de coorte, livre acesso, publicados em inglês, português e espanhol, no intervalo de 2017 a 2022 e faixa etária infantil. Resultados: Os materiais de estudo são triagem neonatal e terapias gênicas, utilizadas para o diagnóstico e tratamento da atrofia muscular espinhal, respectivamente, dentre suas principais aplicações, constituindo impactos no prognóstico e qualidade de vida dos pacientes, frente a uma melhor função motora e obtenção de novos marcos do desenvolvimento infantil. Considerações finais: A triagem neonatal e a terapia gênica oferecem impactos positivos, juntamente com as perspectivas futuras para o tratamento dessa enfermidade, visando um diagnóstico e suporte terapêuticos precoces e mais efetivos.
Metodologias ativas no ensino da bioética: uma avaliação feita por estudantes de medicina
Authors: Pereira Kamilla da Palma , Araújo Laís Záu Serpa de
Published: March 2022

Objetivo: Verificar a avaliação que os estudantes do curso de Medicina fazem das atividades com metodologias ativas desenvolvidas na disciplina de bioética. Métodos: Os participantes da pesquisa foram estudantes do 3º ao 6º ano de graduação em medicina de uma universidade pública de um estado do nordeste do Brasil. Eles tiveram que responder um questionário online que avaliou as atividades com metodologias ativas utilizadas na disciplina. Foi um estudo descritivo, exploratório, prospectivo, com abordagem quantitativa. Resultados: No total 127 estudantes responderam ao questionário, destes 51,2% eram do sexo masculino, a média de idade foi 25 anos e predominaram alunos do 5º ano. A atividade Spikes foi a que os alunos mais gostaram de participar, de assistir e sentiram mais prazer na realização, embora tenha sido considerada a que exigiu mais esforço e a de maior dificuldade na execução. A atividade "caso de bioética clínica" foi a que mais gerou reflexões éticas e desenvolvimento ético, segundo os participantes, enquanto o seminário foi a que gerou maior conhecimento. Conclusão: As metodologias ativas como estratégia de aprendizado proporcionaram maior participação dos alunos, além de prover mais conhecimentos acerca da bioética e suscitar reflexões éticas durante o processo.
Transtorno dismórfico corporal: relação com os padrões de beleza
Authors: Medeiros Leticia Pereira de , Souto Brenda Lohany Cordeiro , Fernandes Vitória Lima , Tristão Maria Luiza Vargas , Dias Lorena Cavalcante , Silva Matheus Andrade , Rocha Larissa Costa dos Santos Oliveira , Nepomuceno Basílio Francisco Vieira , Neto Raymundo Sálvio , Moura Ivan Gilson Silva
Published: March 2022

Objetivo: Analisar a relação entre padrões de beleza e o transtorno dismórfico corporal. Revisão bibliográfica: O Transtorno Dismórfico Corporal (TDC) é definido como uma preocupação excessiva com um defeito físico imaginado por uma pessoa na sua aparência, causando assim um sofrimento que passa a ser de preocupação clínica. Esse padrão de comportamento é geralmente notado em situações sociais, que a pessoa se esquiva socialmente e tenta camuflar sua aparência com maquiagem, gestos e roupas. Outro comportamento típico é examinar repetidamente o “defeito” no espelho ou evitá-lo, podendo ainda pedir reafirmações a respeito. O padrão estético que é proposto, sobretudo pela mídia, já que esta possui maior alcance, influência na forma como as pessoas tratam seu corpo. Apesar de a idade de início ser mais comum durante a adolescência, ocorre também em crianças e idosos. Nesse último, existe uma grande preocupação com o envelhecimento. Considerações finais: O TDC impacta negativamente na vida dos seus portadores, impossibilitando uma vida saudável, tanto no âmbito social, profissional, física e mental.
PROSPECTS FOR THE USE OF ADHESIVE ADDITIVES FOR THE PRODUCTION OF ROAD BITUMEN FROM HIGH-PARAFFIN OIL FIELDS OF THE CHECHEN REPUBLIC
Authors: Цамаева П.С. , Эльмурзаев А.А.
Published: March 2022

Проблема качества дорожных битумов в России была и остается актуальной. Решение данной проблемы видится в применении качественных адгезионных добавок. Применение импортных присадок к битумам существенно повышает их качество, но в то же время весьма существенная разница в ценах по сравнению с аналогами российских производителей. Однако, если анализировать по качеству дорожных покрытий и долговечности, то использование адгезионных добавок зарубежных производителей может быть выгоднее применительно к битумам, планируемых получать из нефтей месторождений Чеченской республики.

The problem of the quality of road bitumen in Russia has been and remains relevant. The solution to this problem is seen in the application of highquality adhesive additives. The use of imported additives to bitumen signifi cantly improves their quality, but at the same time, a very signifi cant difference in prices compared to analogues of Russian manufacturers. However, if we analyze the quality of pavements and durability, then the use of adhesive additives from foreign manufacturers may be more advantageous for bitumens that are planned to be obtained from the oil fi elds of the Chechen Republic.
ESTIMATION OF THE POST-BUCKLING BEHAVIOR OF COMPOSITE PANELS OF NONSYMMETRICAL STRUCTURE WITH RIGID SUPPORT AND TAKING INTO ACCOUNT THE INITIAL DEFLECTION UNDER COMPRESSION AND UNEVEN LOCAL HEATING
Authors: Митрофанов О.В.
Published: March 2022

Получено аналитическое решение задачи об оценке закритического поведения композитной панели несимметричной структуры при сжатии с учетом локального неравномерного нагрева. Исходные данные записаны для случая всестороннего жесткого опирания и учитывают начальную погибь.

An analytical solution to the problem of estimating the postbuckling behavior of a composite panel of a nonsymmetrical structure under compression, taking into account local uneven heating, is obtained. The initial data are recorded for the case of allround rigid support and take into account the initial defl ection.
Prediction and realisation of high mobility and degenerate p-type conductivity in CaCuP thin films
Authors: Willis Joe , Bravic Ivona , Schnepf Rekha R. , Heinselman Karen N. , Monserrat Bartomeu , Unold Thomas , Zakutayev Andriy , Scanlon David O. , Crovetto Andrea
Published: March 2022

Phosphides are interesting candidates for hole transport materials and p-type transparent conducting applications, capable of achieving greater valence band dispersion than their oxide counterparts due to the higher lying energy and increased size of the P 3p orbital. After computational identification of the indirect-gap semiconductor CaCuP as a promising candidate, we now report reactive sputter deposition of phase-pure p-type CaCuP thin films. Their intrinsic hole concentration and hole mobility exceed 1e20 cm-3 and 35 cm2/Vs at room temperature, respectively. Transport calculations indicate potential for even higher mobilities. Copper vacancies are identified as the main source of conductivity, displaying markedly different behaviour compared to typical p-type transparent conductors, leading to improved electronic properties. The optical transparency of CaCuP films is lower than expected from first principles calculations of phonon-mediated indirect transitions. This discrepancy could be partly attributed to crystalline imperfections within the films, increasing the strength of indirect transitions. We determine the transparent conductor figure of merit of CaCuP films as a function of composition, revealing links between stoichiometry, crystalline quality, and opto-electronic properties. These findings provide a promising initial assessment of the viability of CaCuP as a p-type transparent contact.
In-Situ Observation of the Structure of Crystallising Magnesium Sulfate Heptahydrate Solutions with Terahertz Transmission Spectroscopy
Authors: Li Qi , Kölbel Johanna , Davis Margaret P. , Korter Timothy M. , Bond Andrew D. , Threlfall Terrence L. , Zeitler J. Axel
Published: March 2022

Terahertz time-domain spectroscopy in a transmission geometry combined with vi- sual analysis was used to investigate the crystallisation process of MgSO4 solution. Careful spectral analysis of both a feature at 1.6 THz and the baseline allowed the ex- traction of information about the liquid phase before and during crystallisation, aiding the investigation of solvation dynamics and the behaviour of molecular species at phase boundaries. The method was reproducibly applied to a number of measurements on a series of solutions of three chosen concentrations at different temperatures. When increasing temperature at the end of the measurement, the dissolution of crystals was observed as well. The temperature-dependent absorption data of the semi-crystalline systems were converted to the solvent concentrations using a recently developed method. Solutions of a series concentrations were also investigated in the temperature range of 4◦C to 25◦C. The results were compared to the theoretical calculated values, and the consistent differences proved the existence of a hydration shell around the salt ions whose behaviour is different from bulk water. Future work will focus on triggering nucleation at specific positions in order to study the very beginning of the crystallisa- tion process. MgSO4 heptahydrate is used as a model system in this study, while the concept and the set-up can be applied to other systems.
Alleviation of Cocaine Withdrawal and Pertinent Interactions between Salvinorin-based Antagonists and Kappa Opioid Receptor
Authors: Akins Nicholas , Mohammed Salahuddin , Pandey Pankaj , Kim Seong Jong , Mahdi Fakhri , Khan Md Imdadul , Moss Emaya , Worth Charlie , Keane Madeline , Chittiboyina Amar , Doerksen Robert , Paris Jason , Le Hoang
Published: March 2022

The kappa opioid receptor (KOR) is involved in the regulation of both the reward and mood processes. Recent reports find that the use of drugs of abuse increases the production of dynorphin and overall activation of KOR. Long-acting KOR antagonists, such as norbinaltorphimine (nor-BNI), JDTic, and 5'-guanidinonaltrindole (GNTI), have been shown to stop depressive and anxiety-related disorders, which are the common side effects of withdrawal that can lead to the relapse in drug use. Unfortunately, these prototypical KOR antagonists are known to induce selective KOR antagonism that is delayed by hours and extremely prolonged, and their use in humans comes with serious safety concerns because they possess a large window for potential drug-drug interactions. Furthermore, their persistent pharmacodynamic activities can hinder the ability to reverse unanticipated side effects immediately. Herein we report our studies of the lead selective, salvinorin-based KOR antagonist (1) as well as nor-BNI on C57BL/6N mice for spontaneous cocaine withdrawal. Assessment of pharmacokinetics showed that 1 is a short-acting compound with an average half-life of 3.75 h across different compartments (brain, spinal cord, liver, and plasma). Both 1 (5 mg/kg) and nor-BNI (5 mg/kg) were shown to reduce spontaneous withdrawal behavior in mice, with 1 producing additional anti-anxiety-like behavior in a light-dark transition test (however, no mood-related effects of 1 or nor-BNI were observed at the current dosing in an elevated plus maze or a tail suspension test). Our results support the study of selective, short-acting KOR antagonists for the treatment of psychostimulant withdrawal and the associated negative mood states that contribute to relapse. Furthermore, we identified pertinent interactions between 1 and KOR via computational studies, including induced-fit docking, mutagenesis, and molecular dynamics simulations, to gain insight into the design of future selective, potent, and short-acting salvinorin-based antagonists.
Nonacethrene Unchained: A Cascade to Chiral Contorted Conjugated Hydrocarbon with Two sp3-Defects
Authors: Čavlović Daniel , Häussinger Daniel , Blacque Olivier , Ravat Prince , Juríček Michal
Published: March 2022

A dihydro precursor of helical diradicaloid nonacethrene undergoes a reaction cascade triggered by an oxidant to a chiral contorted polycyclic aromatic hydrocarbon named hypercethrene. In this ten-electron-oxidation process, four σ bonds, one π bond, and three six-membered rings are formed in a reaction sequence of up to nine steps to yield a 72-carbon-atom warped framework, comprising two configurationally locked [7]helicene units, fluorescent peropyrene unit, and two precisely installed sp3-defects.The key intermediate in this cascade is a closed nonacethrene derivative with one quaternary center, presumably formed via an electrocyclic ring closure of nonacethrene, which— when activated by oxidation—undergoes an oxidative dimerization of phenalenyl to peropyrene. By controlling the amount oxidant used, two intermediates and one side product could be isolated and fully characterized, including single-crystal X-ray diffraction analysis, and one intermediate was detected by electron paramagnetic resonance spectroscopy. In concert with density functional theory calculations, these intermediates support the proposed reaction mechanism. Compared to peropyrene, the absorption and emission of hypercethrene are slightly red-shifted on account of extended conjugation and the fluorescence quantum yield of 0.45 is decreased by a factor of ~2. Enantiomerically enriched hypercethrene displays circularly polarized luminescence with a CPL brightness value of 8.3 M–1cm–1. This unexpected reaction cascade demonstrates that the reactivity of “unchained”diradicaloid compounds, which is typically considered an undesired feature, can be well-defined and employed as a useful, step-economic synthetic tool toward novel carbon nanostructures.
Sharing is Caring: Guidelines for Sharing in the Electronic Laboratory Notebook (ELN) Chemotion as applied by a Synthesis-oriented Working Group
Authors: Fink Fabian , Hüppe Henrika , Jung Nicole , Hoffmann Alexander , Herres-Pawlis Sonja
Published: March 2022

The documentation and storage of experimental data is crucial in research data management and science in general. With regard to automated data curation and the generation of data for machine learning processes, the collection and sharing of machine-readable data, including negative results, is a key step. The electronic laboratory notebook (ELN) Chemotion provides the possibility to share synthesis data with other researchers taking the mentioned aspects into account. In these guidelines, we offer general information on how to share data in Chemotion and present our sharing policy as a best practice example on how to use Chemotion’s sharing functions in a working group with several group members on various hierarchy levels.
Comparison of Process Parameter of Lab Batches, Scale-Up Batches Exhibit Batches Commercial Batches
Authors: Prakash Gnana
Published: March 2022

The aim of the present work is to evaluate the critical process parameters and techniques and improve the quality and reduce cast and scaling up time. The pharmaceutical industry R & D refers to the process of successful progress from drug discovery to product development. The need to the target market are identified alternative product concept are generated and evaluate and single concept of selected for future development. The concept is a description of the from function and features a product and a usefully. The Scale up is the process as define to increasing the batch size or increasing different physical parameter the output of volume. The old process scale up techniques doesn’t involve studying the critical process parameters (Raw Process). The scale up batches industry to improve quality of the product in moving from Scale up batches/Exhibit Batches and validation batches. To improve the batches quality scale up of a process Transformation of small scale lab batches into commercial scale depended on experience and probability and involving the more technique. Due to this probability of success is less understanding of critical process parameters and process enables control of critical step process parameter during manufacturing and successful transformation from lab scale to Exhibit batches and commercial batches.
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Authors: Prakash Gnana
Published: March 2022

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Formulation and Evaluation of Ketoprofen Emulgels by Model Independent Approach
Authors: Prakash Gnana
Published: March 2022

In the current study, ketoprofen emulgels were prepared using Sodium CMC, Sodium alginate and Hibiscus as gelling agents in order to overcome gastric side effects and to achieve pharmacological response. Pre formulation parameters were performed to know the compatibility of pure drug ketoprofen with polymers CMC, Na alginate, hibiscus prior to the preparation of Emulgel. It indicates that no change was observed in the peak values of the drug in the physical mixture thus providing that both the drug and polymer were said to be compatible with each other. Emulgel of ketoprofen 2.5% w/w was prepared in 3 steps i.e., Preparation of gel, emulsion phases separately and incorporate both phases in homogenizer for a period of 45 min and stabilized it for 2 hrs. The prepared emulgels were evaluated for physical characteristics, drug content, pH, spreadability and in-vitro  permeation studies. The physical appearance of all the formulations was creamy white, consistent, homogenous and stable. The pH of the prepared emulgels was found well within the range of 6-7. Release rate kinetics of the drug was studied with in vitro  drug permeation data for all the formulations F1 to F9 and results were stated the best fit model for selected formulation F6 were found to be Zero order model with non-fickian diffusion. The formulations were compared with the reference product. The in-vitro dissolution of F6 was nearest to the reference product F10 (f2 = 85.17).
Case Study of Acute Liver Failure Due to Large B­-Cell Lymphoma
Authors: Prakash Gnana
Published: March 2022

This case study is about a 72 yrs elderly woman as for acute liver failed due to huge b-cell lymphoma diffusion. The patient was diagnosed with the disease in the past and was on treatment for it. However, she started showing symptoms of fatigue and jaundice which led to hospitalization. The study looks at her medical history and current condition as well as how her disease has progressed over time. It also discusses the various treatments that have been tried so far and their effects on her. A CT scan indicated a huge B-cell lymphoma diffusely involving the liver. The patient underwent an emergency laparotomy and resection of the liver lesion because her condition was deteriorating rapidly. The woman had an enlarged liver (10 cm) with a nodular surface and diffusely increased attenuation on CT scan. She also had a gallbladder wall thickening on ultrasound examination. She has been hospitalized for the further assessment as well as organization of her acute liver fail due to huge B-cell lymphoma dispersion. The seventy two yrs elderly women acute liver problem due to huge B-cell lymphoma dispersion has been hospitalized for such a liver transplant. The patient has been given a diagnosis with huge B-cell lymphoma, that have distributed to her liver. The patients condition worsened incredibly quickly but she was admitted for a liver transplant. Acute liver failure can be caused by many different conditions, including poisoning, drug-induced hepatitis, viral hepatitis, alcoholic hepatitis, autoimmune hepatitis, and hepatic malignancies. Acute liver failure is usually reversible if it is caused by an identifiable cause and if that cause can be treated.
STUDENT'S PERCEPTION TOWARDS THE USE OF EDMODO IN LEARNING EFFECTIVE LISTENING IN THE PANDEMIC COVID-19 PERIOD
Authors: Sama Gratiana , Ota Maria Kristina , Siam Gregoriana Apriliani
Published: March 2022

Virtual class or commonly referred to as online class is one form of learning media that uses the Internet specifically during the quarantine of covid-19. Quantitative descriptive analysis in this study examines the student’s perception of English Literature Study Program Universitas Flores about the use of the Edmodo platform in Effective Listening class at the time of Covid-19 quarantine. The number of samples in this study is 44 students of English Literature Study Program of Universitas Flores who have been taken Effective Listening class during the Covid-19 quarantine period. The result is that Edmodo platform used in Effective Listening class was positive. The average of 98% of English Literature Study Program Students of Flores University   agreed to use Edmodo applications as learning media to learn Effective Listening Class at Covid-19 quarantine time since it is user-friendly. This is because Edmodo's interface looks like a Facebook as social media that students have known in their daily lives
LINGBEE AS INTEREST DRIVEN IN BRAINSTORMING SPEAKING CLASS
Authors: Arifin Rahmatul Ummu , Latifa Ammang , Ammade Salasiah
Published: March 2022

This Research Aims to Measure the Students’ Interest in Brainstorming Speaking Class by Using Lingbe. The Researcher Used Lingbe as The Students’ Interest Driven In Brainstorming Speaking Class. The Researcher Involves Technology in Interactive Learning. In This Case the Researcher Offers an Interactive Application Called Lingbe.A Pre-Experimental Method Was Conducted by The Researcher in This Study. The Population Was The Xii Grade Students Of Mipa Of Sman 2 Barru. Due To This Semester Consisted Six Intact Class (228 Students), The Researcher Used The Cluster Sampling Method In Deciding The Research Sample. The Instruments That Were Used In Collecting The Data Were An Informal Likert’s Scale Questionnaire And  Analysed By Using Spss Application.The Results Of The Research Showed That The Students Stated Interested In Learning English Using Lingbe Assisted By Brainstorming In Their Speaking Class. The Mean Score Of Students’ Interests Was 54.85 And Considered As Moderately Interested.
ENGLISH AS A FOREIGN LANGUAGE (EFL) TEACHERS’ PERCEPTION ON INFORMATION AND COMMUNICATION OF TECHNOLOGY (ICT)
Authors: Mahfira Ega , Abdul Nurdevi Bte , Natsir Ratu Yulianti
Published: March 2022

This research aimed to find out kinds of information and communication of technology (ICT) is used by the teachers’ to teach English at SMP NEGERI 2 MASAMBA and to find out Teachers’ perception on the use of information and communication of technology (ICT) in teaching English. This research used a descriptive qualitative method, the instruments used were observation and interview. The observation was used to observe and interview the English teachers. The findings of the research showed the results of the teachers’ interview showed that mostly the teacher gave positive perception and agreed toward and teachers’ used Information and Communication Of Technology (ICT) in teaching English, they were happy, they left easy to understand the lesson, motivated to learn, being polite, diligent doing assignment. Whereas, some student was unhappy in learning English and got difficulties to understand the lesson because the thought that learning English was difficult.
TEACHERS ROLES AND PARENTAL INVOLVEMENT: IMPLEMENTATION OF 2013 CURRICULUM
Authors: Hamid Sitti Maryam , Purwanti Oikurema
Published: March 2022

The role of the teacher is a pivotal key in the implementation of the 2013 curriculum. Not only the teacher's roles but also parental involvement plays a supporting role to achieve the objectives of implementing the curriculum. In order, collaboration between both is very necessary. In this study conducted a qualitative research method. It involved six informants’; three English teachers and 3 parents from state, private, and religious senior high school in Makassar, South. The instruments used Semi-structured interviews. The interviews were transcribed, coded and analyzed. The main findings and components of this study included the teachers’ roles and parental involvement as an essential source of information. The teacher's role is to apply the 2013 curriculum according to the procedure Which focuses on balance in cognitive, psychomotor, and emotional aspects by integrating subjects with one another. The parental involvement that domains found in this study as followed communicating, volunteering, and learning at home.
THE IMPLEMENTATION 2013 CURRICULUM IN ELTLL: SCIENTIFIC APPROACH AND AUTHENTIC ASSESSMENT
Authors: Mannong Bulkis Maghfirah , Purwanti Oikurema
Published: March 2022

The 2013 curriculum emphasizes on active student learning with a scientific approach and authentic assessment. This paper aims to explicate the teachers’ complexity in implementing the scientific approach  and authentic assessment in English language teaching process. The 2013 curriculum introduces and encourages the use of  scientific approach in the learning process for all subjects including English. Scientific approach is an approach that focuses on finding facts, concepts, principles, laws and theories. By this approach, it is hoped that the students’ learning outcomes can be more attached as they do it with fact based procedure. Withal, authentic assessment is also emphasized in the 2013 curriculum, where this assessment not only focus on the final result but also on the learning process.  This paper  focuses  on : the implementation of scientific approach and authentic assessment in English language teaching process, and the barriers faced by teachers in implementing scientific approach and authentic assessment. Qualitative descriptive was applied in this study. To obtain the data needed, interview was used as instrument in this study. There were several conclusions obtained from the results of this study; 1) The implementation of scientific approach was in accordance with approach. In terms of assessment, the English teacher has implemented the authentic assessment, that is a measurement of students’ learning outcome in three domains (cognitive assessment, affective assessment an skill). But in its implementation, this has also not been implemented in a manner maximum. 2) The barrier faced the principles or rules. In lesson plan, the teachers clearly described the steps of scientific approach with using variety of methods or techniques in teaching English, even though  on the process of teaching and learning English in the class, the teacher rarely used this by the teacher in applying  scientific approach was to facilitate the students in asking and answer questions among them, while in authentic assessment, the obstacles were limited time, limited facilities and infrastructure, difficulty in implementing certain models of authentic assessment, and students.
ASSESSING THE ACQUISITION OF CLAUSE CONNECTORS BY THE FIRST SEMESTER STUDENTS OF STMIK PRIMAKARA IN ACADEMIC YEAR 2019/2020
Authors: Dewi Eka Grana Aristyana
Published: March 2022

The aim of this study is on evaluating the ability of students of STMIK Primakara in the academic year 2019/2020 in mastering clause connectors. The norm-referenced measures of five standard values were used to analyze the data. The students were 187 students who have heterogeneous characteristics as the population. In taking the sample, quota random sampling technique was used. There were 30 students determined as the sample of the study by using quota random sampling technique. The data analysis result showed that: (1) 6.67% had excellent ability; (2) 30.00% had good ability; (3) 13.33% had sufficient ability; (4) 46.67% s had insufficient ability, (5) 3.33% had poor ability in mastering clause connectors. If the outcome of the study were applied as the basis for the sample’s degrees, then there was 50.00% who failed in learning and acquiring clause connectors, and the rest 50.00% was good enough in learning and acquiring clause connectors. It meant that the acquisition of clause connectors by the students was sufficient. The data of the study conducted was considered to have fairly amount of validity and reliability, as there were many factors that could interfere the conclusions. The result of the study conducted can help to improve planning for teaching specifically in understanding clause connectors.
PROMOTING DISCOVERY LEARNING METHOD FOR EFL STUDENTS IN READING COMPREHENSION
Authors: Muliati Muliati , Syam Ulfah
Published: March 2022

This research aims to examine the impact of discovey learning method and to know the significance of discovey learning method on students’ reading comprehension. This research used pre-experimental method with one group in pre test and post test. The treatment conducted after the pre test and before post test. The impact of discovery learning method and the significance of discovery learning method would be considered in learning reading. This research is restricted to students’ reading comprehension in SMPN 01 Barru. The finding revealed that before applying discovery learning method students have difficulties in answering reading comprehension test. Meanwhile, after giving treatment and disrtributing post-test, the students have reading skill increase significantly. However, the students resource issues that are dominated by the difficulties in reading English, the limitation of vocabulary that they have, and the strategies that teacher used in teaching and learning reading. The Significance of the research are expected to provide data and information about the implementing of discovey learning method teaching and learning reading. By knowing the students’ comprehension in reading English, the teacher can apply designing material, strategies, and activities based on their students’ reading comprehension. It is obviously more effectively run the teaching and learning reading in the classroom.
THE USE OF TASK-BASED LANGUAGE INSTRUCTION THROUGH ONLINE VIDEO TELECONFERENCE APPLICATION IN TEACHING SPEAKING SKILL ON ENGLISH DEPARTMENT STUDENTS OF NAHDLATUL ULAMA UNIVERSITY
Authors: Authar Nailul , Afandi Mujad Didien
Published: March 2022

Instruction deals with something that we ask someone to do something. It is also related to approach when we talk about educational area. Task – Based Language Instruction is an approach that in relation with student-centred approach to second language instruction. Young generation in the millennial era 4.0, nowadays, are born in the middle of complete facilities. Everything becomes easier in their life, communication, and education. Moreover, they are supported by good infrastructure of technology. Google, YouTube, Vlog, Website, Media social are tools that support their academic process. This research belonged to qualitative research. Thus, the qualitative method was chosen for this study because it was appropriate with the focus of this research. The data in this study were in the form of utterances produced by the students of English Department of Unusa University which were obtained from observing the teaching learning process and from the interview through online video application. According to the result, there are two benefits that using Task Based Instruction through    online video application in teaching speaking skill. Firstly, it can build more on students’ confidence; secondly, they can develop their speaking skill by collaborating many vocabularies they know. In conclusion, of the use Task Based Instruction, it is the best way for students and lecture in teaching and learning process especially in teaching speaking skill.
TEACHER’S QUESTIONING STRATEGIES IN SCAFFOLDING STUDENTS’ LEARNING AT UNIVERSITY LEVEL
Authors: Milawati Milawati , Rohmah Nurir , Alim Helmy Sahirul
Published: March 2022

Evidence is mounting that teacher questions can assist students in various purposes in the teaching-learning process (Blosser, 2006; Bond, 2007; Cotton, 2007). The teacher tends to deliver a simple to the complex level of question, for the discussion can run smoothly (Bloom’s taxonomy level, 1956). Despite this, a variety of good questions will not guarantee that the interactive classroom will be created, the teacher needs to employ rephrasing, redirecting, probing, and reinforcement in her questioning (Goodwin et al, 1992). However, practically, teachers ask a large number of questions, which somehow they fail in doing questioning strategies (Wragg and Brown, 2001:p.28). This conceptual article describes the teacher’s questioning strategies in facilitating students’ learning and promoting their thinking skills. It highlights the fact that a teacher who has initially lack the ability to teach higher thinking skills can make considerable progress in terms of applying her knowledge in the classroom (Zohar Dori, 2011). This article ends by arguing for some changes that need to occur in effective classroom questioning, including the need to give a stronger description of the extent of the level of question and the questioning strategies, which the teacher employed.
THE EFFECTIVENESS OF GOOGLE CLASSROOM FOR ONLINE DISCUSSIONS
Authors: Afandi Mujad Didien , Saputri Tiyas
Published: March 2022

Covid-19 pandemic brings massive impacts to many life sectors, especially education. Schools and colleges are closed temporarily so that online learning is the only way to continue the education. Of many online platforms and media found on internet, Google Classroom provides features to support the online active learning activities. Therefore, this study is aimed at investigating the effectiveness of Google Classroom for online discussions.By involving 39 sixth-semester students of English Education Program – Universitas Nahdlatul Ulama Surabaya (UNUSA), this descriptive qualitative study captured the comment threads on Google Classroom as the data to describe the number of comments and participants in online discussions. Those data were collected and interpreted to prove that the platform supported written online discussions.The results found that the total number of comments found in 14 meetings was 457 comments which were mostly dominated by the students. The findings showed the students’ increasing participation in online discussions. Google Classroom with its features enables them to minimize the psychological barriers, provide attention, support and motivation in sharing ideas in written comments. Furthermore, notifications sent automatically to the students’ Gmail account is an advantage. In conclusion, Google Classroom is effective to increase the students’ participation in online discussions. With the features provided in the online platform, the students build up more enthusiasm, motivation, attention and support to share comments and ideas during online discussions. Thus, the use of this platform should be taken as a consideration when oral discussions do not work as expected.
THE IMPLEMENTATION OF ROLE PLAY WITH VIDEO BLOGS (VLOG) IN TEACHING SPEAKING TO THE ELEVENTH GRADE STUDENTS OF SENIOR HIGH SCHOOL 3 OF PALEMBANG
Authors: Sapitri Miranti Anggun , Hatim Magdad , Noviati Noviati
Published: March 2022

Speaking Skill is essential in communication as a foreign language, either in educational qualification or in career achievement. The students have intermediate speaking skill potential to gain further education and to find employment. The problem of this research deals with the fact that most of students are lack of speaking skill. First, particularly the eleventh grade students of Senior High School 3 of Palembang are not motivated to learn and increase their speaking skills. Second, consequently the students are not able to act as interlocutors when the communication occurred. The objective of this study was to find out whether or not there is a significant difference of speaking scores of the eleventh grade students taught through Role play with Video blogs (Vlog) from those of the ones taught through a conventional technique at Senior High School 3 of Palembang. This research was True Experimental design (Quantitative). The research was conducted from July to August 2020 by online. The subject of the research was 36 students of the eleventh grade of Senior High School 3 of Palembang. The technique of collecting data used a monologue test. The monologue test was done to know whether there was a significant difference by using role-play with video blogs (vlog) in teaching speaking skill. The students’ average score of the experimental group in the posttest was 53.29 while the students’ average score in the control group was 46.04. Meanwhile the critical value was 0.05 significance level for two-tailed test with 35 (df) was 1.68 since the t-obtained was 11.352, it was higher than the t-table. The result of research showed that there was a significant difference of speaking scores of the eleventh grade students taught through Role-play with Video blog (Vlog) from those of ones taught a conventional technique at Senior High School 3 of Palembang. The use of role play with video blogs (vlog) not only made the students enjoy, fun and relax learning English but also indirectly made the students capable improvise their skill based on their mind.
Mathematical modeling of an unmanned object motion control system in SimInTech environment
Authors: Myznikova V. A. , Ustimenko V. V. , Chubar A. V. , Solopko I. V.
Published: March 2022

In today's world robotic devices are more and more often used to help people. They solve both domestic and industrial problems. When designing any object inevitably have to deal with testing under different conditions. To do this can build a test model, but if the object is quite complex and several models need to be built at once, to save labor and material resources can help mathematical modeling. This article presents mathematical modeling of processes based on typical functional blocks in the form of systems of differential-algebraic equations. Mathematical modeling and control algorithm as a set of interrelated structures are considered. The robot motion is simulated for the forward direction of rotation of wheels, the reverse direction of rotation, and the opposite directions of rotation. A model of the control device, which forms the control actions on the wheel motor according to the value of the deviation of the current orientation of the wheeled robot from the preset one, is constructed. These influences allow you to bring the orientation of the robot to the desired orientation. Quality metrics are obtained for various values of the rotational speed of the work. Although this model neglects the action of many forces that arise during the motion, it allows us to identify the influence on the motion and trajectory of the robot of such factors as the radius of the wheels, the distance between them, the magnitude of the voltage applied to the motors during the turn.
Manajemen Quality of Service pada Jaringan Software Defined Network Menggunakan Opendaylight Controller
Authors: Rozaq Abdur , Suartana I Made
Published: March 2022

Kamajuan teknologi jaringan berkembang sangat pesat. Hal ini mengakibatkan tingkat konfigurasi pada jaringan semakin rumit, sehingga jaringan menjadi tidak fleksibel dan susah diatur. Software Defined Network (SDN) merupakan jaringan yang cukup fleksibel dan dapat dengan mudah untuk diatur. Jaringan SDN ini dapat mengatur dan mengelola sampai ribuan perangkat jaringan melalui pusat manajemen, pengoptimalan pada komponen jaringan meliputi pengoptimalan bandwidth, load balancing, traffic engineering yang bersangkutan dengan programmability dan scalability. Quality of Service (QoS) adalah suatu kemampuan dalam menyediakan layanan lalu lintas jaringan yang berbeda dengan kelas yang berbeda pula untuk menyediakan sebuah layanan jaringan agar menjadi lebih baik dan dapat terencana dengan jitter dan bandwidth yang khusus, serta kemampuan untuk kehilangan sebuah latensi yang dapat terkontrol. Dalam beberapa penelitian menunjukkan bahwa sistem yang telah dibangun dapat berhasil menjalankan manajemen QoS secara baik pada jaringan dan kualitas jaringan dapat meningkat. Tujuan dari penelitian ini adalah untuk melakukan perbandingan dari jaringan SDN yang menggunakan QoS dengan jaringan SDN yang tidak menggunakan QoS menggunakan controller Opendaylight. Dari hasil pengujian yang telah dilakukan kinerja dari jaringan SDN yang menggunakan QoS lebih baik dibandingkan jaringan SDN yang tidak menggunakan QoS baik dalam pengujian yang menggunakan background traffic maupun tidak.
Psoriasis, diagnóstico y tratamiento
Authors: Gudiño Villarreal Nataly Andrea , García Vélez Yiulia Thais , Estévez Angulo Brigith Andrea , Díaz Recalde Eddy Xavier
Published: March 2022

La psoriasis es una enfermedad crónica inflamatoria, cuya manifestación característica es cutánea, tiene diferentes formas de presentación y en los casos más graves puede llegar a ser muy comprometedora. La metodología utilizada para el presente trabajo de investigación, se enfoca hacia una metodología orientada hacia la necesidad de indagar en forma precisa y coherente una situación. Enmarcada dentro de una revisión bibliográfica de tipo documental, ya que nos vamos a ocupar de temas planteados a nivel teórico como es Psoriasis, diagnóstico y tratamiento. La técnica para la recolección de datos está constituida por materiales impresos, audiovisuales y electrónicos, estos últimos como Google Académico, PubMed, entre otros. La información aquí obtenida será revisada para su posterior análisis. Dada las diferentes formas en la que esta patología se puede presentar, es de suma importancia que el médico tratante que tiene que ser un dermatólogo, este al tanto de la fisiopatología, manifestaciones clínicas y complicaciones que puede generar la psoriasis, esto con el fin de poder tener un claro diagnóstico y poder establecer el mejor tratamiento, el cual en algunos casos es complejo (tratamientos sistémicos). Entendiendo que no hay tratamiento curativo, ya que el objetivo del mismo es mejorar los síntomas y disminuir la gravedad y expansión de las lesiones.
Anestesia en cirugía reconstructiva y estética
Authors: Betancourt Enríquez Mónica Elizabeth , Vera Rodríguez Evelyn Esther , Gaibor Robalino Joffrey Duval , Simbaña Carrera Paola Elizabeth
Published: March 2022

La cirugía plástica ha evolucionado a la par de la anestesia de tal forma que ahora se puede satisfacer casi todas las metas de las personas que las solicitan. un medicamento administrado tiene como objetivo de ofrecer un efecto clínico deseado, basado en una concentración terapéutica específica en el sitio de acción Es fundamental que el anestesiólogo esté familiarizado con los múltiples procedimientos quirúrgicos para establecer un abordaje anestésico óptimo, y tener presente que el plan quirúrgico original cambia con frecuencia. Es objetivo de esta investigación exponer los diferentes trabajos sobre anestesiología en las cirugías reconstructivas y estéticas que llevan a cabo los cirujanos plásticos. Las complicaciones de la anestesia se pueden clasificar en cuatro diferentes categorías etiológicas: problemas de salud; eventos adversos a la técnica de la anestesia; el estado físico de los pacientes; y incidentes centinela o eventos. La justificación para la realización de una cirugía plástica no compromete la rigurosidad medica con la que se aborda. Los anestesiólogos refieren que las técnicas de anestesia regional son más recomendables que las de anestesia general los pacientes menosprecian la importancia de la ingesta de estos productos por lo que es imperativo que tanto el cirujano como el anestesiólogo deban investigar enfáticamente si los pacientes ingieren este tipo de productos ya que muchos de ellos tienen actividad anticoagulante, antiplaquetaria, pro coagulante, arrítmica o potencian los efectos de los anestésicos. Los procedimientos relacionados a la cirugía plástica son para pacientes aparentemente “sanos”. Se entienden que el proceso anestésico va desde la evaluación previa a la intervención quirúrgica, pasando incluso por evaluaciones psicológicas respecto a la percepción del paciente respecto al acto quirúrgico hasta la recuperación completa del paciente, incluyendo por supuesto el dolor postquirúrgico. Va a depender de la experiencia con la anestesia del paciente toda la percepción de éxito o fracaso de la intervención quirúrgica.
Sufrimiento fetal agudo en pacientes con preeclampsia con signos de severidad
Authors: Intriago Balda José Vicente , Castro Zambrano José Leonardo , Demera Demera Luís Carlos , Franco Muñoz Valeria Soraya
Published: March 2022

La preeclampsia-eclampsia es un trastorno multisistémico de causa desconocida, que incrementa la morbimortalidad materna y perinatal. En algunos países latinoamericanos, los problemas con mayor regularidad en las gestantes y que producen alteraciones fetales de diferente índole, son los trastornos hipertensivos. La placentación anormal que se produce en la preeclampsia se relaciona con poca o ausente remodelación de las arterias espirales maternas En la preeclampsia y la eclampsia los fetos se encuentran mal oxigenados (hipoxia crónica fetal) y desnutridos, son hipotróficos y algunos recién nacidos presentan lesiones neurológicas irreversibles. El Sufrimiento fetal agudo es cuando el feto presenta asfixia acelerada que puede provocar descomposición de una respuesta fisiológica o un daño que va afectar al sistema nervioso central, deficiencia múltiple de órganos y por ende llega a la muerte fetal. El diagnostico de concluye con los siguientes elementos: acidosis, anoxia, hipoxia, frecuencia cardiaca fetal, asfixia, liquido meconial. Para conseguir el objetivo palteado se ha realizado la búsqueda de artículos científicos, libros, guías, tesis, trabajos de grado y toda publicación de carácter académico derivada de repositorios médicos como PUBMed, Elseiver, Scielo y editoras académicas universitarias. Se ha utilizado el motor de búsqueda Google académico bajo las fórmulas “sufrimiento fetal”, “preeclampsia” y “sufrimiento fetal agudo en pacientes con preeclampsia “, tomando solo las publicaciones por relevancia que aporten una descripción global de los elementos que exponen de manera explícita la relación entre el diagnostico de sufrimiento fetal derivado de una preeclampsia materna, sin descartar las características y consideraciones para un diagnóstico. El sufrimiento Fetal está estrechamente ligado al desarrollo de enfermedades hipertensivas, sin embargo, dichas afecciones maternas afortunadamente tienen elementos preventivos que conllevan a un pronóstico favorable al momento de cuidar el desarrollo de nuevas vidas. Aunque el Sufrimiento Fetal engloba unas posibles consecuencias para el recién nacido, no necesariamente ligadas a la muerte, sino que es importante resaltar que la posibilidad de desencadenar efectos neurológicos a largo plazo invita a potenciar los mecanismos preventivos para evitarlo.