bluuebunny/crossref_metadata_2025 huggingface dataset:
Implication of Mode of Consumption of Allium cepa L. (Onion) on Lipoglycemic and Anthropometric Impacts in Diabetic Rats: A Function of Choice
Authors: Anyakudo Magnus Michael Chukwudike
Published: February 2022

Background: Use of Allium cepa L. (Onion) as spice in traditional cooking, concoctions and preparations has long been established since ancient time. However, the implication of its mode of consumption on health benefits is inadequately considered or explored. Objectives: This experimentally-controlled designed nutritional study aimed to determine and compare the effects of consumption of Allium cepa in its raw form and in mixed meal on body weight, glycemic tolerance/control and, lipid profile in diabetic rats. Materials and Methods: Twenty one adult (170-200g) male Wistar rats were randomly categorized into three experimental groups (n=7, each): Diabetic Control (DC), Diabetic Onion Extract-Treated (DOE), and Diabetic Onion-supplemented Diet-Fed (DSO). Diabetes was inducted with 150 mg/dL, alloxan monohydrate solution intraperitoneally. Animals were fed according to the experimental design with water ad libitum for six weeks. Body weights and Fasting blood sugar (FBS) concentrations were measured twice weekly. LP and OGTT were conducted. Microsoft Excel and statistical SPSS program version 22 were used for data analysis. Results are expressed as mean ± SEM. Comparison between groups were made using Students’t-test and one way ANOVA. Results: Consumption of onion in its raw (aqueous extract) form caused more reduction in blood glucose concentration (DOE - 38.14% versus DSO - 11.2%; P = 0.02) and body weight gain (DOE -7.71% versus DSO - 16.32%; P = 0.01), with improved lipid profile than when ingested in mixed meal (supplemented diet). Glycemic response curves peaked at 60 minutes of glucose challenge in DSO and DOE groups. Conclusion: Mode of consumption of Allium cepa, influenced its therapeutic anthropometric and lipoglycemic effects in diabetic rats.
The Association Between Body Mass Index and Glycemic Control in Patients with Type 2 Diabetes Across Eight Countries: A Literature Review
Authors: Boye Kristina S
Published: February 2022

Objectives: To investigate the association between obesity and glycemic control based on country-specific glycemic control data from the USA and selected European and Asian countries by body mass index (BMI), or BMI data by glycemic control (HbA1c), in individuals with type 2 diabetes (T2D). Methods: Literature search of databases and abstracts to identify real-world studies (2015-2020) reporting HbA1c and BMI data. Results: Seventeen articles (China, including Hong Kong, n=10; Japan, n=3; USA, n=2; Spain, n=1; UK, n=1) were identified from 6696 de-duplicated references. Of the 13 studies reporting by BMI mean rates of glycemic control or likelihood of achieving glycemic control, eight found that achieving control significantly declined as BMI increased; one reported a clear trend but no statistics; two reported glycemic control rates for those with obesity to be significantly worse than for one other group; and two reported no significant difference with BMI. Of the six studies reporting average HbA1c levels by BMI, four reported HbA1c to increase with BMI. Two of three studies reporting mean BMIs by glycemic control found these increased with HbA1c. Conclusions: This review consolidates recent evidence on the glycemic control status of individuals with T2D reported by BMI in selected countries. Studies generally reported a lower chance of achieving glycemic control targets in those with overweight or obesity. Most studies found greater HbA1c in individuals with higher BMI, and average BMI greater in those with higher levels of HbA1c. Focused efforts are needed to improve glycemic control in patients with T2D and overweight/obesity.
Strategi dan Metode Menghafal Al-Qur'an di Pondok Tahfidz Darul Itqon Lombok Timur
Authors: Arini Junita , Widawarsih Winda Wahyu
Published: February 2022

Hasil penelitian dan pembahasan penelitian ini yaitu: (1) Strategi menghafal Alquran di Pondok Tahfizh Darul Itqon Bilasundung adalah dengan strategi pengulanagan per 1 juz, 3 juz, dan muraja’ah kelompok, pembiasaan menggunakan satu jenis mushaf, selalu memperhatikan ayat yang serupa, tidak berpindah ayat sebelum ayat yang dihafalkan benar-benar hafal. (2) Metode menghafal adalah metode wahdah, metode sima’i, menggabung hafalan baru dengan yang lama, membuat target hafalan, semaan dengan sesama teman hafizh, dan memperbanyak membaca Alquran. (3) Faktor-faktor yang menjadi penghambat dan pendukung dalam menghafal Alquran: (a)Faktor Penghambat tidak menguasai makhraj dan tajwid, jarang muraja’ah, tidak bisa membagi waktu antara sekolah dengan menghafal, rasa malas, dan kurang konsentrasi. (b) Faktor pendukung menghafal Alquran di Pondok Tahfizh Darul Itqon adalah kesadaran diri sendiri yang meliputi cita-cita menjadi hafizh Alquran dan keinginan membalas jasa orang tua serta motivasi yang meliputi dorongan orang tua dan nasihat berharga dari pimpinan pondok Tahfizh Darul Itqon.
PERPUSTAKAAN KOMPREHENSHIF DALAM TEKNOLOGI PENDIDIKAN (Analisis Kitab Al-Maktabat As Syaamilah Fi Tiknulujiyya At-Ta’lim Karya Dr. Ibrahim Abdul Fattah Yunus)
Authors: Ramzi Muhajirin -
Published: February 2022

Teknologi Pendidikan sebagai sebuah pengembangan teknologi dalam dunia pendidikan baik dalam sebuah perencanaan, aplikasi dan lain sebagainya atau dengan kata dengan adanya teknologi maka sebuah pendidikan akan lebih baik dalam perencaan dan mengevaluasi suatu pembelajaran. Pemahaman tentang perpustakaan bagi sebagian masyarakat umum, nampaknya masih konvensional atau masih berangkapan bahwa perpustakaan hanya sebuah gedung tempat penyimpanan berbagai macam buku sebagai bahan bacaan atau referensi.  Padahal dengan semakin berkembangnya ilmu pengetahuan dan teknoloagi, fungsi dan tugas  perpustakaan juga ikut berkembang sesuai dengan zaman. lembaga pendidikan Islam mempunyai tanggung jawab membersiapkan dan menghasilkan sumberdaya manusia yang mampu menghadapi semua tantangan perubahan yang ada disekitarnya yang berjalan sangat cepat. Bahkan sebagai dampak globalisasi mengakibatkan terjadinya persaingan secara bebas dalam dunia pendidikan maupun tenaga kerja. Kondisi tersebut menuntut perlu adanya suatu sistem pendidikan yang bermutu yaitu sistem pendidikan yang mampu menyediakan sumberdaya manusia yang dapat bersaing. Makalah ini akan lebih fokus menganalisis Al-Maktabat As Syaamilah Fi Tiknulujiyya At-Ta’lim karya Dr. Ibrahim Abdul Fattah Yunus yang membahas secara konfrehenshif tentang “Al-Maktabat As Syaamilah” teknologi pendidikan.
CANUDOS/PARAGUAI
Authors: De Barros de Albuquerque Adenilson
Published: February 2022

Este artigo analisa os romances históricos Canudos de Antônio Conselheiro (2018), de Hélio de Araújo, e Paraízo-Paraguay (2019), de Marcelo Labes. O objetivo é destacar as principais confluências e/ou novidades que essas publicações recentes da literatura brasileira apresentam em relação a uma longa lista de romances latino-americanos – sobre os respectivos temas da Guerra de Canudos (1896-1897) e da Guerra do Paraguai (1864-1870) – estudados por Albuquerque e Fleck (2015) e Albuquerque (2020).
HISTÓRIA E LITERATURA EM DIÁLOGO
Authors: Pacheco de Andrade Celeste Maria , Javier Lopez Cristian , Candido Weslei Roberto
Published: February 2022

Os diálogos entre o discurso da historiografia com a ficção possibilitam-nos um amplo espaço de reflexão sobre o poder das palavras e suas múltiplas interpretações. A confluência da História com a Literatura encontra nos gêneros híbridos um ponto de convergência importante para o estudo das ressignificações do passado, no intento do cultivo do pensamento decolonial. Neste artigo, apresenta-se uma breve reflexão sobre a relação desses dois ramos do saber, materializada em um poema histórico: o Romanceiro da inconfidência mineira (1953), de Cecília Meireles (1901-1964). São fundamentos da análise apresentada neste texto os pressupostos de Fleck (2017), Larios (1997), Burke (1993), Castro-Gómez e Grosfoguel (2007), entre outros.
A LEITURA LITERÁRIA NA ESCOLA
Authors: Fernandes Matilde , Spiess Simone , Souza Santos Luciene
Published: February 2022

Neste artigo analisamos a narrativa Barriga e Minhoca, Marinheiros de Cabral (2002) de Atílio Bari em comparação à Carta de Pero Vaz de Caminha (1500), comentários de Leandro Garcia Rodrigues (2019). Discutimos as possíveis relações entre história e literatura, convergências e divergências entre os discursos sobre o passado presentes na literatura híbrida de história e ficção infantil, embasados nos estudos de Cadermatori (1987), Coutinho (2003), Carvalhal (2006), Nitrini (2010), Candido (2011), Colomer (2017), Fleck (2017), Coelho (2020) sobre literatura comparada. Buscamos desconstruir, a partir da ficção, as “verdades” impostas pelo discurso oficial e alcançar o processo de descolonização necessário.
LIBERDADE AINDA QUE TARDIA - A INSERÇÃO DA LITERATURA JUVENIL COMO POSSIBILIDADE DE RESSIGNIFICAR O ENSINO DE HISTÓRIA
Authors: Sacomori Candido Pedro Fernanda , Rafael Facchinello Douglas , Da Silveira Corsi Margarida
Published: February 2022

Este artigo analisa comparativamente o evento histórico da Conjuração Mineira (1789) nas obras A Viagem Proibida: nas Trilhas do Ouro (2013), de Mary Del Priore, e História Sociedade & Cidadania (2018), de Alfredo Boulos Junior. O cotejo das duas obras, realizado a partir dos pressupostos de Hutcheon (1991), Burke (1992), Trouche (2006), Fleck (2017) e Bernd (1998), demonstra que a narrativa híbrida de história e ficção enseja outras formas de reflexão a respeito de fatos históricos e promove a conscientização do leitor.-
TUMBU (2007): DA LIBERDADE NA ÁFRICA À ESCRAVIDÃO NO BRASIL – RESSIGNIFICAÇÕES DO PASSADO ESCRAVAGISTA PELA LITERATURA HÍBRIDA JUVENIL E A FORMAÇÃO DO LEITOR CONSCIENTE
Authors: Camargo Marta Richciki , CORRÊA Raimundo Nonato Duarte , Santos Vilson Pruzak dos
Published: February 2022

Neste artigo objetivamos dar visibilidade a uma narrativa híbrida de história e ficção juvenil intitulada Tumbu (2007), de Marconi Leal. Essa obra propõe uma releitura do passado da escravidão do povo negro por meio de uma voz enunciadora marginalizada pela historiografia tradicional. Com isso, também, buscamos formar leitores que sejam capazes de ler além da decodificação de palavras, que sejam leitores conscientes da manipulação da linguagem, pois é, desde nosso ponto de vista, essencial para a formação de uma sociedade descolonizada. Para isso, nos ancoramos em Colomer (2001), Coelho (2010), Fleck (2017), entre outros.
MAR PARAGUAYO
Authors: Lovera de Florentino Nádia Nelziza
Published: February 2022

Estruturado a partir de um relato híbrido que se estabelece nas fronteiras entre os gêneros, entre as línguas e entre as culturas, Mar paraguayo se constitui como um romance ímpar, capaz de instigar reflexões de diversas naturezas. Nessa perspectiva, este trabalho se propõe a articular o hibridismo, a devoração cultural antropofágica observadas no romance a um movimento em direção à descolonização à libertação das imposições do colonialismo e do neocolonialismo e das estruturas discursivas do poder. São utilizadas as conceituações de Santiago (2000) e Mignolo (2003), além de outros teóricos dos estudos literários e culturais para em um primeiro momento demonstrar o trânsito entre as fronteiras presentes desde o título do romance e posteriormente relacionar esse trânsito a uma via de descolonização e bilinguajamento. Por fim, o trabalho evidencia o labor artístico com a linguagem presente no romance e que revela a representação do ser fronteiriço e seu discurso sem fronteiras que questiona a tradição e as gramáticas, o colonialismo e o neocolonialismo.
A (DES)CONSTRUÇÃO DA CULTURA BRASILEIRA E SUA RESSIGNIFICAÇÃO NA TRADUÇÃO DE CASA GRANDE E SENZALA (1933) E MACUNAÍMA (1978)
Authors: De Freitas Santos Aline , Cristina dos Santos Costa Elaine , Nunes Barreiros Patrício
Published: February 2022

Gilberto Freyre e Mário de Andrade foram dois intelectuais do Modernismo brasileiro que, movidos pelo mesmo propósito, contribuíram significativamente para a (re)construção da identidade nacional. Em suas obras, Casa Grande & Senzala ([1933] 2006) e Macunaíma ([1928] 1978), respectivamente, eles problematizam questões até hoje ainda não superadas pela sociedade brasileira. Apresentamos, neste artigo, as estratégias de (des)construção e valorização da cultura brasileira a partir de alguns MC’s. Além disso, esboçamos como algumas lexias foram ressignificadas na tradução interlinguística de CG&S por Barandiarán, e de Macunaíma por Héctor Olea.
COLOMBO REVISITADO
Authors: Paiola Luana , Oliveira Valdeci Batista de Melo
Published: February 2022

Esta pesquisa estuda a ressignificação da figura histórica de Cristóvão Colombo no romance The Memoirs of Christopher Columbus (1987), de Stephen Marlowe, com o intuito de verificar as aproximações e os distanciamentos do descobridor, o herói consagrado pela historiografia e pelos romances históricos tradicionais. Assim, objetivou-se compreender a recriação do personagem sob o olhar de um estadunidense pós-moderno, comparando a visão do navegador em suas cartas, com base nas certezas na razão e verdade Ocidentais. O resultado da efabulação de Marlowe aproxima Colombo do moderno sujeito fragmentado no afã de significar a si mesmo e descobrir o mundo.
A POESIA DE HERZER NUM EXERCÍCIO DE DECOLONIZAÇÃO DOS CORPOS
Authors: Rodrigues Walace
Published: February 2022

Este artigo busca pensar sobre a poesia do poeta transsexual Anderson “Bigode” Herzer (1962-1982), nascido como Sandra Mara Herzer, ou simplesmente Herzer, como uma criação literária que revela uma tentativa de decolonização do corpo humano. Os poemas foram retiNossa metodologia para este artigo foi trabalhar com uma revisão conceitual a partir de uma bibliografia selecionada e fazer uma análise de sentidos dos poemas selecionados. Tais poemas foram retirados do único livro de Herzer, intitulado A queda para o alto (de 1982, lançado pela Editora Vozes). Os resultados revelam que a poesia de Herzer mostra um claro mecanismo de interrogação dos corpos dominados e subjugados social e moralmente, mostrando uma tentativa de um pensamento decolonial, apesar de não claramente explicitado.
O ROMANCE HISTÓRICO NO CONTEXTO DA NOVA NARRATIVA LATINO-AMERICANA:
Authors: Klock Ana Maria
Published: February 2022

Neste artigo perpassamos as veredas trilhadas pela literatura hispano-americana na sua trajetória de enfrentamento às versões eurocêntricas e o alcance dessas transformações na produção escritural recente. É nosso intento, dentro desse escopo, recuperar como tal processo dá-se a partir de adaptações efetuadas na nova narrativa hispano-americana após os engendramentos do boom, com ênfase ao romance híbrido de história e ficção, gênero que bem ilustra esse caminho de transformações e inovações no âmbito literário em   nosso continente. Sob o intuito de contemplar como o romance híbrido sustenta, nas manifestações recentes do gênero, intenções críticas frente ao discurso eurocêntrico colonizador, tomamos para a análise expressões pertencentes ao eixo temático do “descobrimento” da América, demonstrando, a partir disso, que as narrativas, embora relativizando os pressupostos experimentalistas formais e linguísticos herdados do período do boom, mantêm assinalado o caráter altamente crítico em relação a como releem a história.
BORDERS & RAILS (B&R)
Authors: Sousa Vanda Maria , Neves Rúben , Di Fátima Branco , Abreu João , Santos Francisco Sena
Published: February 2022

Estabelecida há 724 anos, a raia fronteiriça da Península Ibérica é a mais extensa da Europa. Borders & Rails (B&R) – Narrando & Partilhando a Paisagem Raiana, assenta em dois eixos performativos da linguagem – a retórica e a poética - promovendo uma representação da raia, nas narrativas multimédia e gamming, fazendo uso do formato storytelling e numa abordagem transdisciplinar – antropológica (na relação cultural do homem com a paisagem), ontológica e a fenomenológica (no pressuposto heideggeriano de da-sein e derridiano da consciência da própria nudez), da experienciação prática à narratologia da paisagem, gerando ainda um repositório de experiências imersivas da paisagem.
XICOTÉNCATL (1826) NO POLISSISTEMA LATINO-AMERICANO E A SUA TRADUÇÃO
Authors: Berndt Jorge Antonio , Shaí Del Pozo González Leila , De Lima Cerdeira Phelipe
Published: February 2022

Este artigo toma a tradução ao português brasileiro de Xicoténcatl (1826) para exemplificar a teoria dos polissistemas (EVEN-ZOHAR, 1978) nos estudos da tradução. Sublinha-se como a ressignificação da personagem Hernán Cortés na diegese permite a (des)construção de certos saberes (SOUSA SANTOS, 2010; QUIJANO, 2014), tensionando um dado constructo imposto pela linhagem historiográfica rankeana e motivando os intelectuais no entre-lugar do discurso latino-americano (SANTIAGO, 2000). Estão circunscritas à nossa análise as recentes discussões sobre as fases e modalidades do romance histórico (FLECK, 2017), ademais de elaborações para pensar na ficção histórica no contexto latino-americano (WEINHARDT, 2011), (CERDEIRA, 2019), entre outros.
A TRADUÇÃO LITERÁRIA DE OBRAS LATINO-AMERICANAS
Authors: Antunes Keven de Almeida , Fleck Gilmei Francisco , Barreiros Liliane Lemos Santana
Published: February 2022

Esse trabalho tem como objetivo investigar os impactos da domesticação na tradução literária, partindo da análise do romance Gabriela, cravo e canela ([1958] 2006), de Jorge Amado para a língua inglesa, seguindo os conceitos de Venuti (1995; 2008) de Estrangeirização e Domesticação, bem como o aporte teórico de estudos que contribuem para a discussão sobre a ética da tradução. O nosso corpus de estudo é paralelo, composto por marcadores culturais da obra Gabriela, cravo e canela ([1958] 2006) e sua tradução Gabriela, clove and cinnamon ([1962] 1988). Os resultados da análise demonstraram uma tendência domesticadora na tradução dos marcadores culturais e, por consequência, o apagamento da cultura baiana para o leitor estrangeiro, regida pelo objetivo de traduzir o romance de Jorge Amado como um best-seller nos Estados Unidos.
EL ENUNCIADO DE/SOBRE LA VIOLENCIA EN LA NOCHE DE TLATELOLCO, DE ELENA PONIATOWSKA
Authors: Rodríguez Mercedes Magdalena
Published: February 2022

En nuestro trabajo abordamos el volumen La noche de Tlatelco(1971) y efectuamos una propuesta de análisis. Ésta se centra en las representaciones de la violencia advertidas en el relato testimonial a partir del desenlace trágico que silencia el Movimiento Estudiantil de 1968 en México. Adoptando una perspectiva foucaultiana, indagamos la constitución del enunciado que articula redes de representaciones simbólicas sobre ese acontecimiento. Y, destacando la imposibilidad de una relación transparente en los mecanismos de la memoria, situamos la lectura entre los pliegues de lo intertextual a fin de interceptar el proceso de mediación/traducción sobre los desplazamientos de la experiencia traumática.
Identifying the Formative Factors which Shape Individual Intention to Prefer Imported Used or Locally Assembled Cars: A Survey on Pakistan
Authors: Hussain Talha , Zafar Muhammad Zeeshan , Toor Areeba , Ajmal Hamayel
Published: February 2022

The current study intended to examine the consumer intention while purchasing locally assembled and imported cars. Hence, the study proposed a model which is underpinned with social identity theory. The research model employed consumer ethnocentrism, self-congruity product characteristic, perceived relative price, brand personality and service quality. The current study identify research gap and found to the best knowledge of researchers that past study is lacking the determinants which motivate consumer intention, separately, to select local or imported cars. Moreover, aforementioned studies reported inconsistent results about consumer inclination towards automobile selection. The sample size of the study was 396. The proposed model was analyzed using structural equation model. The finding of the study revealed that consumer intention to purchase locally assembled and imported cars are shaped by both factors like rational and emotional. In addition to the results unveiled the fact that consumer purchase intention towards locally assembled cars highly influenced by ethnocentrism, brand personality as well as product characteristics. In continuation with the brand personality has highest explanatory power for making consumer intention towards imported cars. In contrary to that while purchasing imported cars the consumer influenced by self-congruity and brand personality. In addition to perceived relative price and service quality having insignificant effect on both cars. The present study confirmed that in collectivism society the purchase of automobile shaped by emotions and social influences. Although the study contributed in literature with theoretical and practical implication nevertheless suggested some future research direction.
The Mechanisms for Influencing Green Purchase Intention by Environmental Concern: The Roles of Self-Green Image Congruence and Green Brand Trust
Authors: Klabi Fethi , F. Binzafrah
Published: February 2022

This study is the first to examine a serial mediation model that includes environmental concern, self-green image congruence, green brand trust, and green purchase intention. Based on data from a sample that included 349 Saudi individuals, the analyses supported most mechanisms flowing from environmental concern to self-image congruence and green brand trust in serial. The direct relationship of environmental concern to green purchase intention was also statistically significant. This study provides an interesting perspective on the antecedents of green purchase intention. From a managerial perspective, the results show that cognitive, psychological and motivational mechanisms could enhance green markets in an Arab and Islamic country.
Impact of Financial Decisions on Firm Performance: Path Analysis Approach
Authors: Maqbool Asifa , Sheikh Nadeem Ahmed
Published: February 2022

This study intended to explore causal relationships between the corporate performance and financial decisions of the firms which are listed on the Pakistan stock exchange (PSX). This study has used Return on assets and Tobin's Q as the measures of accounting performance and market performance respectively. To effectively examine the causal structure of corporate financing, investment, dividend payout decisions, and the firm performance simultaneously this study has used path analysis approach. The sample comprises 292 non-financial firms which are listed on the Pakistan Stock Exchange (PSX). The findings clearly show that debt financing has positive effect on the investment and dividend has negative effect on the investment decisions. The debt financing and investment has a negative impact on corporate performance while dividend decisions has a positive impact on corporate performance. This study helps to understand the corporate decision making process of Pakistani firms. To the author's knowledge this is the first study attempted to check the application of path analysis in emerging economies to study the causal structure of corporate financial decisions and corporate performance.
Reimaging a Canadian National Security Strategy
Authors: Shull Aaron
Published: February 2022

On November 26, 2021, Mr. Aaron Shull, Managing Director and General Counsel at the Centre for International Governance Innovation (CIGI), presented on Reimaging a Canadian National Security Strategy at the 2021 CASIS West Coast Security Conference. The presentation was followed by a question and answer period with questions from the audience and CASIS Vancouver executives. The key points discussed included CIGI’s new project to address Canada’s national security strategy gap and what it will take to accomplish the goals that could derive from the recommendations provided.
Repairing the Relationship between Law Enforcement and the Public
Authors: Lucki Brenda
Published: February 2022

On November 25, 2021, Commissioner Brenda Lucki of the Royal Canadian Mounted Police (RCMP), presented Repairing the Relationship between Law Enforcement and the Public at the 2021 CASIS Vancouver West Coast Security Conference. The primary focus of Commissioner Lucki’s presentation was the law enforcement agency’s initiative and pathways to re-earn the public’s trust and strengthen bonds. The presentation was followed by a question and answer period with questions from the audience and CASIS Vancouver executives.
Analysis of the development of cryptocurrency instruments
Authors: Lukyanov A. A.
Published: February 2022

Objective. The aim of the work is to determine the prospects for the development of digital financial instruments in the management of social and economic systems. Method. The comparative analysis of the results of an anonymous survey using interactive multi-user social networks was used as research methods in the work. Result. The factors and key parameters influencing the development of cryptocurrency mechanisms are revealed, the advantages and disadvantages of using digital tools are identified. Suggestions for the management of cryptocurrency instruments and recommendations for improving the reliability and development of digital instruments in the financial and digital environment are given. The results of the analysis of a survey of 1121 respondents on the topic of using cryptocurrencies are presented. The results of the study showed that the most commonly used cryptocurrencies are Bitcoin and Ethereum, with a significant proportion of respondents preferring digital activities such as mining and trading. At the same time, a significant number of respondents believe that the future development of digital financial instruments is directly dependent on the legitimization of cryptocurrencies by the state and improvement of blockchain technology. Conclusion. The development of cryptocurrencies cannot be assessed unambiguously. With the development of cryptocurrency instruments, a number of threats arise, which include significant volatility, the presence of legislative restrictions on their use, and the inability to withdraw operations. The further development of cryptocurrencies should be associated with the legal regulation of their distribution, both at the national and international levels, which will ensure the determination of their legal status among other monetary units. It is also necessary to carry out a phased introduction of cryptocurrencies into payment systems for cash settlements, which should be carried out on the basis of the organization of the official circulation of cryptocurrencies and blockchain technology.
Modeling of erosion processes in open channels
Authors: Magomedova M. R.
Published: February 2022

Objective. The aim of the study is to model erosion processes in open channels.Method. A stochastic approach is applied to the calculation of parameters and the construction of models of individual stages of the erosion process: disruption, weighing and transport of eroded soil particles by a turbulent flow. Result. A technique has been developed for predicting the general erosion of riverbeds and canals, composed of homogeneous and heterogeneous non-cohesive soils. Approbation of the developed technique on the material of laboratory and field studies confirmed its satisfactory accuracy in a wide range of hydraulic conditions and soil granulometric compositions. Conclusion. The principles of developing a model of erosion processes in open channels, the modular structure of the calculation algorithms and programs compiled on its basis, allow us to continuously improve the methods for calculating individual parameters of the erosion process and make adjustments to the corresponding modules of algorithms.
Verification of the computing process of the corporate information system
Authors: Polyakov V. I. , Zinnatulin F. F.
Published: February 2022

Objective. The article discusses the issue of verifying the computing process of a corporate information system. The purpose of the article is to verify the computing process of a corporate information system. Method. The method of verifying the computational process of a corporate information system is a graphic-analytical model and a software model of the computational process.Result. The result is a successful verification of the computing process of the corporate information system. Conclusion. The conclusion of the article is that the computational process of a corporate information system can be verified using graphic-analytical and software models. The process of verification of the computing process of a corporate information system is presented on the example of a corporate information system 1C: Enterprise. The computational process goes through the architecture of the corporate information system and performs its tasks.
Evaluating the effectiveness of using the intelligent adaptive training system for design modules based on printed circuit boards
Authors: Hoang K. K. , Donetskaya Yu. V.
Published: February 2022

Objective. The article studies the problem of adequate assessment of the level of acquired knowledge and skills with design of modules based on printed circuit boards (PCB) using CAD PCB. The article considers the issue of assessing the effectiveness of the use of an intelligent adaptive training system, which is the fundamental criterion for the effectiveness of the training process for designing of modules based on PCB. This intelligent adaptive training system of design of modules based PCB enables learners to assess their own performances. The main purpose of the study is to substantiate the algorithm and mathematical models of the developed system for assessing the effectiveness of training using an intelligent adaptive system. Method. The parameters, algorithm and patterns of building intelligent adaptive learning systems for designing modules based on PCB of ship integrated control systems for future specialists are disclosed. Result. The target indicators of the effectiveness of training in the design modules based on PCB are highlighted. A fully functional algorithm for assessing the effectiveness of learning the design modules based on PCB in intelligent adaptive systems is determined by the step of technological operations to ensure the uniformity of the learning quality control. Conclusion. This system can be useful for teachers and specialists-studying the design modules based on PCB. This system can be used at the stage of assessing the achievable characteristics which can significantly speed up the learning process. The research methods are applied in training the design modules based on PCB to the personnel of the shipyard X52 in Vietnam. It is suitable not only for training shipyard personnel to work, for teaching various levels of training of personnel of any industrial enterprise, for example, in aircraft engineering, mechanical engineering or instrument making, and for teaching any CAD system in general.
Determination of coordinates of the earthquake hypocenter with a known structure of the earth's crust
Authors: Aslanov T. G. , Sidorkina Yu. A.
Published: February 2022

Objective. The aim of the study is to develop methods for determining the coordinates of the hypocenter of an earthquake with a known structure of the earth's crust. Method. To solve the problem, the brute force method, the confidence interval, the comparative method and the enumeration of possible options on the grid are used. Result. A method has been developed for determining the coordinates of an earthquake source with a known structure of the earth's crust using points of various figures of the n-th order as geometric locations in calculations. Conclusion. The proposed method, with the known structure of the earth's crust, makes it possible to use all known methods that require information on the travel time differences of seismic waves to spaced seismic sensors and the difference in travel times of longitudinal and transverse seismic waves to the seismic sensor for calculating the coordinates of the earthquake hypocenter. The accuracy of determining the coordinates of the earthquake hypocenter depends on the quality of determining the structure of the earth's crust on which the seismic event was observed.
Formation of streams of binary sequences with controlled structure of "cellular" automata in homogeneous register environments
Authors: Kadiev P. A. , Nazarov K. K. , Kardashova Z. G.
Published: February 2022

Objective. Development of a method for organizing the process of forming flows register structure, patented by the author at the Department of DSTU, which is a cellular automaton of binary sequences with a controlled structure of "cellular" automata in homogeneous register environments. Method. To solve the set system problem, a process model was built in order to determine the factors that allow changing the sequence of flow elements. Result. When studying the most common generators of pseudo-random streams based on linear register media with modulo two adders in feedback circuits, which are "cellular" automata, it was established from the tables of environment states that the factors determining the structure of the generated streams of binary sequences are the sequence of states , are the initial state of the register of a homogeneous medium and the feedback structure determined by the transition function of the cellular automaton. Conclusion. It is shown that by varying the initial state of the cellular automaton and the structure of feedbacks as control tools, it seems possible to form binary pseudo-random streams of states with different structures, different order of flow elements, bringing their characteristics closer to random ones. Examples of the implementation of the flow structure control process are given, confirming this assumption. A typical structure of a stream shaper with a managed structure based on a homogeneous one is given.
Assessing Physician’s Motivational Communication Skills: 5-Step Mixed Methods Development Study of the Motivational Communication Competency Assessment Test
Authors: Gosselin Boucher Vincent , Bacon Simon , Voisard Brigitte , Dragomir Anda I , Gemme Claudia , Larue Florent , Labbé Sara , Szczepanik Geneviève , Corace Kimberly , Campbell Tavis , Vallis Michael , Garber Gary , Rouleau Codie , Diodati Jean G , Rabi Doreen , Sultan Serge , Lavoie Kim ,   Network For Health Behavior Change And Promotion (CAN-Change)
Published: February 2022

Background

Training physicians to provide effective behavior change counseling using approaches such as motivational communication (MC) is an important aspect of noncommunicable chronic disease prevention and management. However, existing evaluation tools for MC skills are complex, invasive, time consuming, and impractical for use within the medical context.

Objective

The objective of this study is to develop and validate a short web-based tool for evaluating health care provider (HCP) skills in MC—the Motivational Communication Competency Assessment Test (MC-CAT).

Methods

Between 2016 and 2021, starting with a set of 11 previously identified core MC competencies and using a 5-step, mixed methods, integrated knowledge translation approach, the MC-CAT was created by developing a series of 4 base cases and a scoring scheme, validating the base cases and scoring scheme with international experts, creating 3 alternative versions of the 4 base cases (to create a bank of 16 cases, 4 of each type of base case) and translating the cases into French, integrating the cases into the web-based MC-CAT platform, and conducting initial internal validity assessments with university health students.

Results

The MC-CAT assesses MC competency in 20 minutes by presenting HCPs with 4 out of a possible 16 cases (randomly selected and ordered) addressing various behavioral targets (eg, smoking, physical activity, diet, and medication adherence). Individual and global competency scores were calculated automatically for the 11 competency items across the 4 cases, providing automatic scores out of 100. From the factorial analysis of variance for the difference in competency and ranking scores, no significant differences were identified between the different case versions across individual and global competency (P=.26 to P=.97) and ranking scores (P=.24 to P=.89). The initial tests of internal consistency for rank order among the 24 student participants were in the acceptable range (α=.78).

Conclusions

The results suggest that MC-CAT is an internally valid tool to facilitate the evaluation of MC competencies among HCPs and is ready to undergo comprehensive psychometric property analyses with a national sample of health care providers. Once psychometric property assessments have been completed, this tool is expected to facilitate the assessment of MC skills among HCPs, skills that will better support patients in adopting healthier lifestyles, which will significantly reduce the personal, social, and economic burdens of noncommunicable chronic diseases.
Project Based Learning for Globalisation during the Pandemic in One Junior High School: A Case Study
Authors: Sato Kate J. M.
Published: February 2022

In 2002, MEXT (the Ministry of Education, Culture, Sports, Science and Technology in Japan) announced an action plan for the improvement of English language education with the aim of developing “Japanese who can use English” (Hashimoto, 2009). Furthermore, with globalisation impacting our classrooms “young people need to have the ability to communicate exchange, criticise, and present information and ideas” (Ananiadou & Claro, 2009). However, teachers need to follow prescribed curricular. Therefore, teachers in Japan need to take action to offer opportunities for their students to use English as a tool for communication. This paper details a case study of a project-based communication task for 8 junior high school students ranging from 1st to 3rd grades, in one school. The project was adapted from an out-of-class oral research project to an in-class collaborative written communication project in response to the limitations imposed by the COVID-19 pandemic. While goals of the project were achieved, results indicate that students were not aware of what they were learning and additionally their motivation declined. This paper will be of interest to teachers who desire to equip students with global skills through project-based learning in junior high schools.
BIFURCATION OF SUPERIOR ARTICULAR FACETS OF ATLAS VERTEBRA: A CASE STUDY IN DRY BONES
Authors: MOHANTY SMRUTI REKHA , PANIGRAHI MAMTA , SENAPATI SUSMITA , SN SAMAL
Published: February 2022

Objective: The objective of the study was to see the superior articular facets (SAF) of atlas vertebrae for complete bifurcation.
Methods: In a number of 50 atlas vertebrae with 100 SAF were studied for the tendency to complete separation in the Department of Anatomy and Forensic Medicine of Kalinga Institute of Medical Sciences, Bhubaneswar during the period of January 2015 to January 2016.
Results: Out of 50 atlas vertebrae (100 AF), we observed complete bifurcation on both sides in 14 atlas vertebrae (28 sides) and complete bifurcation right side only in six atlas vertebrae and complete bifurcation left side only in 14 atlas vertebrae. The results were compared with those of other studies and were statistically analyzed.
Discussion: The clinical significance of this study has been thus discussed with a reference to its possible effect on the restriction of the neck movement at the atlanto-occipital joint.
Conclusion: This study is of great importance to the clinicians for doing any clinical facet procedure in the neck region.
ASSESSMENT OF EFFICACY AND SAFETY OF ORAL FOSFOMYCIN SINGLE DOSE IN UNCOMPLICATED URINARY TRACT INFECTION AT A TERTIARY CARE HOSPITAL IN SOUTH INDIA
Authors: REDDY B SASHIDHAR , YADAV M MANOJ KUMAR , S MANISHA , SAI SREE SANGI REDDY , HEMA KAMALA SUNKARA
Published: February 2022

Objectives: Urinary tract infection (UTI) affects 150 million people worldwide each year. The rise in the UTIs is attributed to multidrug-resistant pathogens for which there are minimal treatment options available. This has facilitated the reemergence of certain old antimicrobials such as fosfomycin trometamol (FT). It seems an alternative, but the evidence towards its therapeutic efficiency is scanty. The objective of the study is to evaluate the safety and efficacy of single dose of FT in treating uncomplicated UTI and the resultant variations in the intensity of symptoms after the treatment.
Methods: The study is a prospective, observational, and open-label study in the outpatient unit of the Department of General Medicine, RVM institute of Medical Sciences, for 6 months. The study comprises 50 patients among the age group of 18–70 years. Urinary Tract Infection Symptom Assessment questionnaire was used for the evaluation of symptoms pre and post treatment. After the diagnosis of uncomplicated UTI, patients were treated with single-dose of FT.
Results: The study comprises 22 males and 28 females. After the treatment, there was a drastic improvement in the condition of patients. The severity level reduced and the quality of life improved post treatment and the results were statistically significant. Among 50 patients treated with the drug, 11 patients reported the side effect of diarrhea.
Conclusion: Single dose oral Fosfomycin (3 g) regimen is effective in managing uncomplicated UTI with minimal side effects.
INCIDENCE AND OUTCOME OF MULTIDRUG RESISTANT AEROBIC GRAM-NEGATIVE BACTERIA CAUSING VARIOUS CLINICAL INFECTIONS
Authors: USHARANI PURIMITLA
Published: February 2022

Objective: The purpose of the present study was to isolate, characterize, and evaluate Gram-negative antibiotic bacteria isolated from different clinical samples.
Methods: The Clinical and Laboratory Standard Institute guidelines were used to isolate and identify microbial isolates on Muller–Hinton agar using standard bacteriological techniques and to monitor for antibiotic susceptibility by disc diffusion method.
Results: The study involved 129 clinical samples that were obtained from 70 males and 59 females. A maximum number of cases were recorded in the age group 51–60 (33%) followed by 41–50 (16%). The results showed that the common isolates were Escherichia coli 49 (37%), Klebsiella spp. 37 (28%), Pseudomonas aeruginosa 30 (23%), and among 12% microbial isolates, four isolates were Proteus species, seven isolates were Citrobacter species, and two isolates were Providencia species. The most of the isolates were multidrug resistant isolates. However, few isolates showed sensitivity to meropenem and imipenem and most of them were colistin sensitive. Out of 129 isolated microorganisms, 53 isolates were again screened for carbapenemase production through modified Hodge test. It was found that 50 strains were positive for carbapenemase producers (94%) and three strains were negative for carbapenemase production (6%). E. coli and P. aeruginosa followed by Klebsiella species showed carbapenemase production. Among the 50 strains that were positive for the development of carbapenemase, 47 strains were susceptible to colistin that was identified by the “E” strip method and three strains showed resistance to colistin.
Conclusion: The study allows clinicians to select the right antimicrobial agent that not only leads to improved treatment but also helps to avoid the emergence of drug resistance strains which are still sensitive.
FORMULATION DEVELOPMENT AND EVALUATION OF NIOSOMAL GEL OF COLLECTIVE ANTI-FUNGAL AGENTS
Authors: NIKAM VIKRANT , MANIYAR SIMRAN
Published: February 2022

Objectives: Tea tree oil (TTO) and Eucalyptus oil (EO) are essential oils derived from the leaves and terminal branches of Melaleuca alternifolia and Eucalyptus globulus. Both oils have narrative topical antifungal agents. Niosomal vesicles were chosen for Tea tree and EO dispersion in this investigation because of their ability to protect enclosed drugs, reduce drug dose amount, target drug delivery, increase residence time and penetration.
Methods: TTO and EO containing niosomes were made using a modified thin-film hydration process and Carbopol 934 as a gelling agent to produce a smooth antifungal niosomal gel.
Results: TTO and EO entrapment efficiency was found to be 84.89±0.19% and 86.86±0.57%, respectively, and percent cumulative drug diffusion of TTO and EO was found to be 84.21% and 85.22% in the prepared optimized batch [N9]. Transmission electron microscopy revealed vesicular, spherical particles in the nano range with a smooth surface. The optimum batch [N9] of niosomal gel was made with 1% w/w carbopol 934. TTO 84.9% and EO 86.89%, respectively, were found to have prolonged drug release in an in vitro release investigation utilizing the dialysis bag method. The G9 batch niosomal gel was found to be stable by performing an accelerated stability study for 3 months.
Conclusion: It was concluded that the best formulation batch G9 shows better-sustained release, enhanced residence time, and stability.
A PROSPECTIVE STUDY ANALYSIS OF LIMB LENGTH DISCREPANCY FOLLOWING TOTAL HIP ARTHROPLASTY
Authors: SANABOYINA APPALA RAJU , A V SARASWATHI
Published: February 2022

Objective: The present study was designed and implemented to assess the incidence and occurrence of LLD in post-hip arthroplasty and also to evaluate the causes of limb length discrepancy both intra- and post-operative period to manage total hip arthroplasty effectively.
Methods: It is a prospective study involving 52 patients underwent for THA and conducted in the Department of Orthopedics, Tertiary Care Hospital, Visakhapatnam, India from the period of January 2013 to December 2019. The study used Southern approach or “Moore” approach. All the patients are assessed for limb length discrepancy immediately after the surgery and followed at 6 weeks, 3 months, and after 6 years.
Results: Three patients had significant limb length discrepancy among the 52 patients (5.77%) while the remaining had no significant discrepancies in all X-rays which assess the radiological discrepancies in length. The study yields a satisfactory result as very few patients reported LLD during follow-up period and outcomes such as pain alleviation, walking capacity, limping, and patient satisfaction were insignificantly influenced by leg lengthening (p≤0.05).
Conclusion: A combination of pre-operative templating, intra-operative marking and usage of intra-operative image intensifier and an understanding of anatomy, biomechanics of hip, and implant design would reduce the error of limb length discrepancy.
QUANTITATIVE DETERMINATION OF RESIDUAL SOLVENTS IN PALONOSETRON API BY HS-GC METHOD
Authors: GODE SUNNY GRACE , GOLLAPALLI VIJAYA LAKSHMI
Published: February 2022

Objectives: Palonosetron is an antidote to 5-HT3 in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). The presence of residual solvents in pharmaceutical drug substances or products, as well as excipients, can have a detrimental effect on the product’s quality and stability. These substances must be evaluated for safety and efficacy. The primary purpose of this work is to establish a method for validating and quantifying residual solvents in palonosetron API using Head Space Gas Chromatography (HS-GC).
Methods: In the proposed HS-GC technique for the quantifying residual solvents - ethanol, acetone, methanol, acetonitrile, and isopropyl alcohol (IPA) in Palonosetron API, the headspace equilibrium was achieved at 100°C and analyzed by DB-624 column (30 m × 0.24 mm, 1.8 μm) with injector and detector temperature set at 200°C and 230°C respectively. The dissolving solvent was dimethyl sulfoxide (DMSO). After the initial holding time of 5mins, the temperature was increased to 120°C from 40°C in 20mins at a rate of 10°C/min using a flow rate of 10 ml/min and a split ratio of 1:25 with nitrogen as carrier gas. The approach created has been validated and quantified as per International Conference on Harmonization’s (ICH) guidelines.
Results: All the results obtained were within the ICH specified limits. The validation results for repeatability studies (%RSD values) were found to be <10; recovery studies values were in the range of 90–110% and for the selected linearity range 25–150 μg/ml the correlation coefficients(γ2) for all the solvents were observed to be >0.99.
Conclusion: A sensitive, simple, precise, and economic HS-GC method with Flame Ionization Detector (FID) was developed and validated to quantitatively determine the residual solvents in Palonosetron API.