bluuebunny/crossref_metadata_2025 huggingface dataset:
Multimodal Discourse Analysis of Communicative English for Chinese Learners (Integrated Course) From the Perspective of Ecosophy
Authors: Song Xu , Perry Melissa Shamini
Published: September 2023

Textbooks may reflect a certain ecosophy through the linguistic elements of the content that significantly influences students’ values. This analysis selected 88 discourses from the reading sections of Communicative English for Chinese Learners (Integrated Course), from Books 1 to 4, designed for undergraduate English majors. Based on Systemic Functional Linguistics, the title and the illustration of the reading sections are analyzed to ascertain whether the ideology they reflect is in accord with the ecosophy, that is, the harmonious coexistence of humans, nature, and the development of society. After conducting a textual analysis, all multimodal discourses that can reflect clear ecosophy conform to this idea. Concerning illustrations, seven of them are at variance with the ecosophy. As for the analysis of the logico-semantic relations between image and text, only three discourses are found at variance with the ecosophy, but in actual pedagogical context, these three discourses aim to arouse the thinking of the audience about people’s inappropriate conduct and arouse their ecological consciousness.
A retrieval model of surface geochemistry composition based on remotely sensed data
Authors: He Jinxin , Chen Debo , Zhan Ye , Ren Xiaoyu , Li Qingyi
Published: September 2023

The geochemical sampling work in the difficult and dangerous areas is very hard; hence, it can be greatly improved by combining with the remotely sensed data. Thus, a retrieval model is proposed by Kernel Principal Component Analysis and Artificial Bee Colony (ABC) optimized Support Vector Machine (SVM) models based on Landsat 8 remotely sensed data and the geochemical data in the study area. The analysis results show that the geochemical data delineate the areas with relatively enriched elements, but indicate the low-abnormal ore (chemical) points, and the anomalies delineated by the inversion data are better for this purpose, for better indication. At the same time, the distribution and intensity of the corresponding abnormal areas found that the abnormal areas delineated by the inversion data basically contain the abnormal areas delineated by the original data, and the anomalies located at the ore spots are obviously enhanced; it shows that the SVM model of ABC Optimization can establish the relation between geochemistry data and remote sensing data, can supply the original data effectively, and can also provide the direction for the next prospecting work.
The research of a novel flocculant mainly prepared by Moringa seed meal
Authors: Shen Lu , Zheng Yi
Published: September 2023

As a product of oil extraction from Moringa seeds, Moringa seed meal contains a large amount of flocculant active substances, which are not effectively utilized at present. The concentration of 50 mg L−1 Moringa seed meal extract could be prepared by the mixture of Moringa seed meal defatted powder (100 mesh) and NaCl solution (0.5 mol L−1). According to the share ratio, a novel natural flocculant was formed from 10 mL Moringa seed meal extract (50 mg L−1), 11.94 mg cactus powder (60 mesh) as well 2 mL sodium alginate solution (5 mg L−1). The experimental result suggested that for 400 mL of 100 NTU kaolin suspension, the turbidity removal effect of flocculant was 93.1 % with no increase in turbidity during the resting process, testifying to its biodegradability and ecological safety.
Wear and residual stress in high-feed milling of AISI H13 tool steel
Authors: Bakirci Altug , Koca Selim , Erdogan Ozlem , Cakir Mustafa Cemal
Published: September 2023

With the new manufacturing technologies, it has been possible to machine hard metals efficiently. During high-speed machining (HSM) of high-strength steel, the poor surface integrity of the workpiece affects the performance of the process. Surface roughness, microstructure, microhardness and residual stress are key performance indices for surface integrity directly controlled by tool wear and cutting parameters. In this study, high-feed milling (HFM) of a pocket on test samples made of DIN 1.2344 ESR mould steel with 55 HRc hardness was carried out on the CNC vertical milling machine. Three different cutting speeds and five different feed rates were used. At the end of the machining, tool wear was measured using a microscope. Subsequently, X-ray diffraction and hole drilling procedures were used to quantify residual stresses on machined test specimens. The results showed that under cutting conditions, the highest tensile residual stress was attained at f

z
 = 0.78 mm·tooth−1, v = 127.58 m·min−1, and the highest compressive residual stress at f

z
 = 0.5 mm·tooth−1, v = 127.58 m·min−1, on the workpiece surface. The most suitable cutting parameters were reported as f

z
 = 0.63 mm·tooth−1 and v = 70 m·min−1 cutting speed when tool wear and residual stresses are considered together.
A review of magnetically driven swimming microrobots: Material selection, structure design, control method, and applications
Authors: Liu Huibin , Guo Qinghao , Wang Wenhao , Yu Tao , Yuan Zheng , Ge Zhixing , Yang Wenguang
Published: September 2023

Magnetically driven swimming microrobot is a typical one in the family of microrobots and they can achieve navigation and manipulation in low Reynolds number biomedical environments with an external magnetic drive strategy. This study reviews recent advances in material selection, structure design, fabrication techniques, drive control method, and applications for magnetically driven swimming microrobots. First, the materials used in magnetically driven swimming microrobots were introduced and the effect of material selection on performance was discussed. Second, structure design of swimming microrobots and manufacturing techniques are reviewed, followed by a discussion on the main advances in effective motion control, path planning, and path tracking. Then, the multi-applications of magnetically driven swimming microrobots including targeted drug delivery, cell manipulation, and minimally invasive surgery are summarized. Finally, the current challenges and future directions of the work on magnetically driven swimming microrobots are discussed.
Das „Unternehmen“ im Unionsrecht: Rechtsträger oder wirtschaftliche Einheit?
Authors: Zimmermann Anton , Habrich Victor , Korn Laura , Weller Marc-Philippe
Published: September 2023

399Der Unternehmensbegriff durchzieht das gesamte Wirtschaftsrecht der Europäischen Union. Als Dreh- und Angelpunkt kommt dem Begriffsverständnis, insbesondere in Haftungsfragen, überragende Bedeutung zu. Mangels einer ausdrücklichen, vor die Klammer gezogenen Begriffsbestimmung bedarf es einer gesonderten Analyse der einzelnen Teilrechtsgebiete. Dabei ergibt sich ein klares Bild. Außerhalb des Kartellrechts wird ein enger Unternehmens­begriff verwendet, der das Unternehmen mit der einzelnen juristischen Person bzw. Gesellschaft gleichsetzt. Allein im Kartellrecht ist der Unternehmensbegriff an der wirtschaftlichen Einheit orientiert – ausnahmsweise und nicht verallgemeinerbar.
Los pronombres interrogativos complejos del españolel quéylo qué
Authors: Eguren Luis , Sánchez López Cristina
Published: September 2023

The neuter interrogative pronounsel quéandlo quéalternate withqué‘what’ in conversational Spanish in certain contexts and types of wh-questions (e.g., –No me lo puedo creer – ¿No te puedes creer qué/el qué/lo qué?). This paper describes geographical, register and social variation in the use ofel quéandlo quéand analyses the interpretive and distributional properties of these complex forms. Building on corpus data and speakers’ judgements, it is shown that the formel quéis common to all Spanish dialects and is used in all registers and at all social levels, whereaslo quéis only found in Spain, Argentina and Uruguay: in Spain and Argentina, this form belongs to lower class people with little education and speakers in rural areas; in Uruguay, it does not have a social bias and occurs in both formal and informal situations. It is also argued thatel quéandlo quéare used to indicate that the target of the question is identifiable in the context of utterance, and it is thus claimed thatelandloinel quéandlo quéare overt definiteness markers.
APRESENTAÇÃO
Authors: Edimar de Souza José , Quadros Rückert Fabiano , Luís dos Santos Rodrigo
Published: September 2023

Investigar instituições representa compreendê-las nas suas mais complexas relações sociais. Como o próprio termo indica, se refere ao instituído, trata-se de entidades que asseguram elementos centrais de uma sociedade e que se identificam em diferentes áreas que compõem o tecido social, como política, economia, cultura e a educação. O dossiê propõe acolher pesquisas que analisam os processos de transformações ocorridas no campo da historiografia da educação, as perspectivas teóricas e metodológicas no procedimento de pesquisas sobre instituições escolares e o patrimônio cultural e histórico educativo. Nesse sentido, as investigações que analisam práticas e culturas desenvolvidos em distintos espaços e tempos, a continuidade e descontinuidade dos processos de escolarização formal desenvolvidos em: colégios, grupos escolares, escolas étnicas e comunitárias, escolas isoladas; bem como se interessa pelos estudos do cotidiano, dos modos de fazer, de organizar e ainda das relações entre cultura da escola e cultura material escolar; dos fundamentos da Cultura Escolar; das contribuições da Cultura Escolar no ensino e na pesquisa histórica como produção de memória e do patrimônio histórico, cultural e educativo. Além disso, serão recebidos artigos que compreendam o patrimônio como bens culturais, uma vez que se encontram em constante processo de construção e reconstrução, compreendendo os usos, expressões, conhecimentos, técnicas, objetos, artefatos que produzem os diferentes grupos sociais na vida em comunidade.
Edição Especial: Dossiê “América Andina”
Authors: Luciana Maria de Aragão Ballestrin
Published: September 2023

É com imensa satisfação que a RSulACP lança em seu terceiro número o Dossiê “América Andina”. O Dossiê reúne dois conjuntos de artigos dedicados ao entendimento da realidade política,econômica e cultural da Região Andina, composta por Chile, Colômbia, Peru, Venezuela, Bolívia e Equador. Sua concepção surgiu após a realização do Seminário de Estudos Latino-americanos“Interpretando os Andes: os novos paradigmas para o século XXI”, ocorrido em junho de 2013, na Universidade de Integração Latino-americana (UNILA), com o financiamento do CNPq. A presenteedição conta, portanto, com alguns artigos apresentados no âmbito deste encontro e da recepção pela chamada pública e aberta do Dossiê.
MiR-134 And MiR-106b Are Circulating Biomarkers For Temporal Lobe Epilepsy: Pilot Study Results
Authors: Lysova Kristina D. , Usoltseva Anna A. , Domoratskaya Ekaterina A. , Areshkina Irina G. , Shnayder Natalia A. , Dmitrenko Diana V.
Published: September 2023

Temporal lobe epilepsy (TLE) is among the most common forms of focal epilepsy in adults. Currently, scientists search for microRNAs as noninvasive epilepsy biomarkers. MicroRNAs constitute a class of short (or small) non-coding RNAs that control the level of gene expression affecting the stability of mRNA. They are key regulators and therapeutic targets in epilepsy. Considering the role of miRNA-134 and miRNA-106b in the processes of epileptogenesis, the goal of our study was the clinical evaluation of their circulation as novel noninvasive molecular diagnostic markers of TLE. Material and Methods — Our pilot study involved 59 participants. The main group included 33 patients with mesial temporal lobe epilepsy, the control group encompassed 26 healthy volunteers. The ranking of patients was carried out depending on the disease duration, presence of epileptiform activity on the electroencephalogram (EEG) and hippocampal sclerosis on MRI, the number of taken antiepileptic drugs (AEDs), and patient response to the pharmacotherapy of epilepsy. The isolation of circulating microRNAs from blood plasma was accomplished via the sorption method, and the analysis of microRNA expression was performed by real-time PCR. Results — The expression levels of miR-134 and miR-106b in blood plasma in patients with TLE were reduced. Therefore, these microRNAs can be diagnostic biomarkers of patients with TLE, compared with the control group. The results of receiver operating characteristic (ROC) analysis yielded high sensitivity and specificity values of this biomarker for the diagnosis of TLE. Conclusion — Circulating miR-134 and miR-106b concentrations were significantly reduced in patients with mesial TLE (MTLE), compared with healthy controls. At the same time, the level of microRNA expression did not depend on the presence of hippocampal sclerosis and the response to antiepileptic therapy.
The results of periodic and dispensary medical examination of Kursk Region population in 2022
Authors: Ryndina Vera V. , Pashina Irina V. , Breusov Aleksey V.
Published: September 2023

Objective: to analysis of indicators of preventive medical examinations and dispenserization of the adult population of Kursk, districts and the Kursk region as a whole, development of medical and organizational measures to achieve planned indicators. Material and methods. Analysis of data from form 131 and copying of information from the summary reports of medical institutions by cluster analysis and grouping of indicators depending on the achievement of the plan, extensive indicators were calculated, the results are presented in bar charts. Results. All districts and cities of the Kursk region are divided into three clusters. The first cluster (at least one of the features must reach 100% fulfillment) included 6 districts. The second cluster (districts with the implementation of the plan from 50%) included 21 districts and three cities of the Kursk region. The third cluster (districts with the implementation of the plan up to 50%) included 1 district. Conclusion. The analysis made it possible to identify areas with a low level of completeness of coverage of the adult population with preventive medical examinations and dispenserization. In these areas, it is necessary to resume the work of volunteer detachments with the population to educate them in order to achieve the planned indicators.
Is ongoing testosterone required after pubertal induction in Duchenne muscular dystrophy?
Authors: Wood Claire L , Hollingsworth Kieren G , Bokaie Edrina , Hughes Eric , Muni-Lofra Robert , Mayhew Anna , Mitchell Rod T , Guglieri Michela , McElvaney Joseph , Cheetham Timothy D , Straub Volker
Published: September 2023

Glucocorticoids (GCs) reduce inflammation and preserve muscle function in boys with Duchenne muscular dystrophy (DMD) but cause pubertal delay. Pubertal induction with testosterone is recommended but longer-term outcome is unknown.

Objective

To assess hypothalamic–pituitary–gonadal axis, muscle volume and function 5 years after pubertal induction.

Methods

A prospective observational follow-up of a clinical study was conducted. 15 GC-treated males with DMD were treated with incremental testosterone for 2 years (end of regimen +2 years) then evaluated at +2.5 years and +5 years (final follow-up ~3 years after last injection). Data collected included testicular volume (TV), gonadotrophin, testosterone, inhibin B, muscle function, and limb muscle MRI.

Results

Participants were 18.7 years (s.d. 1.6) at the final follow-up and had been on GC for 11.2 years (s.d. 2.2). Testosterone levels were similar at +2.5 years (8.6 nmol/L (s.d. 3.4) and 5 years (11.0 nmol/L (s.d. 6.1). TV increased from 2.8 mL (s.d. 0.9) at +2 years to 7.1 mL (s.d. 1.8) then 10.6 mL (s.d. 3.5) at +2.5 years and +5.0 years (P < 0.001). Inhibin B levels increased from 55.6 pg/mL (s.d. 47.0) at baseline to 158.2 pg/mL (s.d.87.6), P =0.004 at 5 years but remained lower than reference values (mean 305 pg/mL). Muscle contractile bulk decreased.

Interpretation

Pubertal induction with testosterone in DMD is associated with HPG axis activation and ongoing increases in inhibin B, TV, and testosterone concentrations. Some patients have normal levels which is promising regarding future fertility. Given the beneficial impact of testosterone on bone health, muscle, and well-being, monitoring testosterone levels in this population and supplementation of sub-optimal levels is important.
RET fusion genes in pediatric and adult thyroid carcinomas: cohort characteristics and prognosis
Authors: Bulanova Pekova Barbora , Sykorova Vlasta , Mastnikova Karolina , Vaclavikova Eliska , Moravcova Jitka , Vlcek Petr , Lancova Lucie , Lastuvka Petr , Katra Rami , Bavor Petr , Kodetova Daniela , Chovanec Martin , Drozenova Jana , Matej Radoslav , Astl Jaromir , Hlozek Jiri , Hrabal Petr , Vcelak Josef , Bendlova Bela
Published: September 2023

Thyroid cancer is associated with a broad range of different mutations, including RET (rearranged during transfection) fusion genes. The importance of characterizing RET fusion-positive tumors has recently increased due to the possibility of targeted treatment. The aim of this study was to identify RET fusion-positive thyroid tumors, correlate them with clinicopathological features, compare them with other mutated carcinomas, and evaluate long-term follow-up of patients. The cohort consisted of 1564 different thyroid tissue samples (including 1164 thyroid carcinoma samples) from pediatric and adult patients. Samples were analyzed for known driver mutations occurring in thyroid cancer. Negative samples were subjected to extensive RET fusion gene analyses using next-generation sequencing and real-time PCR. RET fusion genes were not detected in any low-risk neoplasm or benign thyroid tissue and were detected only in papillary thyroid carcinomas (PTCs), in 113/993 (11.4%) patients, three times more frequently in pediatric and adolescent patients (29.8%) than in adult patients (8.7%). A total of 20 types of RET fusions were identified. RET fusion-positive carcinomas were associated with aggressive tumor behavior, including high rates of lymph node (75.2%) and distant metastases (18.6%), significantly higher than in NTRK fusion, BRAF V600E and RAS-positive carcinomas. Local and distant metastases were also frequently found in patients with microcarcinomas positive for the RET fusions. ’True recurrences’ occurred rarely (2.4%) and only in adult patients. The 2-, 5-, 10-year disease-specific survival rates were 99%, 96%, and 95%, respectively. RET fusion-positive carcinomas were associated with high invasiveness and metastatic activity, but probably due to intensive treatment with low patient mortality.
“Whether or not there will be a Great Russia, but one must be orthodox in any case”: the question of “Russia — Europe” dichotomy in the historiosophic views of G. V. Florovsky of the “Eurasian” period of his work
Authors: Dubonosov Alexander
Published: September 2023

This article is an attempt to show the development of historiosophic views of G.V. Florovsky during "Eurasian" period of his creativity on the example of his critique of the idea of "cultural-historical morphology" by N.S. Trubetskoy. The Eurasian movement, whose participants and founders were Florovsky and Trubetskoy, was characterized at an early stage of its development by a considerable ideological and ideological pluralism of its participants. It is noted that Florovsky's historiosophic views began to take shape even before he joined the Eurasian movement. As a result of the revision of the established historiosophy of Russian thought, Florovskij comes to criticize the concept of N.J. Danilevskij, to the continuers of whose ideas Florovskij included N.S. Trubetskij. Despite his disagreement with Troubetzky's ideas, which later became the basis for the "scientific" stage of Eurasianism, Florovskij takes part in the first collections "Exodus to the East" and "On the Roads. The correspondence between Florovsky and Trubetskoy shows that Florovsky's gradual development of historiosophic views and his shift of interest from the problem of nationality (from the dichotomy "Russia-Europe") to the problem of building religious culture leads him to a gradual departure from Eurasianism.
Invasive Bacterial Infections in Children With Sickle Cell Disease: 2014–2019
Authors: Gaschignard Jean , Koehl Bérengère , Rees David C. , Rincón-López Elena , Vanderfaeillie Anna , Pascault Alice , Allali Slimane , Cela Elena , Odièvre Marie-Hélène , Hau Isabelle , Oliveira Marisa , Guillaumat Cécile , Brousse Valentine , de Montalembert Mariane , Navarro Gómez Maria Luisa , Beldjoudi Naima , Bardon-Cancho Eduardo Jesus , Epalza Cristina ,   BACT-SPRING study group, Benkerrou Malika , Gaschignard Jean , Koehl Berengère , Pascault Alice , Brousse Valentine , Allali Slimane , de Montalembert Marianne , Odièvre Marie-Hélène , Hau Isabelle , Guillaumat Cécile , Blais Sophie , Runel-Belliard Camille , Pellegrino Béatrice , Malric Aurore , Guitton Corinne , Gouraud François , Petras Marie , Bensaid Philippe , Basmaci Romain , Eyssette-Guereau Stéphanie , Pham Luu-Ly , Bardon-Cancho Eduardo J. , Cela Elena , Gómez Maria Luisa Navarro , Rincon-Lopez Elena , Ruiz-Llobet Anna , Adan Rosa , Puyo Pablo Velasco , Recasens Valle , Epalza Cristina , Perez-Alonso Vanesa , Torrent Montserrat , Gomez Amanda Bermejo , Vázquez Angeles , Rodríguez Raquel Portugal , Alfaridi Huda , Almaghrabi Rana , Hoyoux Marie , Vanderfaeillie Anna , Oliveira Marisa , Ferreira Teresa , Rees David
Published: September 2023

BACKGROUND

Children with sickle cell disease (SCD) are at a high risk of invasive bacterial infections (IBI). Universal penicillin prophylaxis and vaccination, especially against Streptococcus pneumoniae, have deeply changed its epidemiology. Analysis of IBI in children with SCD in a post-13-valent pneumococcal vaccine era is limited.

METHODS

Twenty-eight pediatric hospitals from 5 European countries retrospectively collected IBI episodes in SCD children aged 1 month to 18 years between 2014 and 2019. IBI was defined as a positive bacterial culture or polymerase chain reaction from a normally sterile fluid: blood, cerebrospinal, joint, or pleural fluid and deep surgical specimen.

RESULTS

We recorded 169 IBI episodes. Salmonella spp. was the main isolated bacteria (n = 44, 26%), followed by Streptococcus pneumonia (Sp; n = 31, 18%) and Staphylococcus aureus (n = 20, 12%). Salmonella prevailed in osteoarticular infections and in primary bacteremia (45% and 23% of episodes, respectively) and Sp in meningitis and acute chest syndrome (88% and 50%, respectively). All Sp IBI occurred in children ≤10 years old, including 35% in children 5 to 10 years old. Twenty-seven (17%) children had complications of infection and 3 died: 2 because of Sp, and 1 because of Salmonella. The main risk factors for a severe IBI were a previous IBI and pneumococcal infection (17 Sp/51 cases).

CONCLUSIONS

In a post-13-valent pneumococcal vaccine era, Salmonella was the leading cause of bacteremia in IBI in children with SCD in Europe. Sp came second, was isolated in children ≤10 years old, and was more likely to cause severe and fatal cases.
Rheology and sensory properties of microencapsulated propolis-enriched stirred-type yogurt
Authors: Taşdemir Yasemin , Gölge Evren
Published: September 2023

In this study, the rheological, sensory and syneristic properties of yogurt enriched with 0.5%, 1% and 2% microencapsulated propolis (MP) was investigated. The viscosity measurements of stir-type yoghurt were performed with Brookfield DV-II viscometer. Shear rate varying between 0.02 s-1 and 100 s-1 flow models was obtained for rising and descending curves with the Rheocalc v3.3 software. Three flow models—Power Law, Herschel–Bulkley, and Casson models—were evaluated. All samples used in this analysis showed non-Newtonian and pseudoplastic properties. During the 21-day storage period, the Power Law flow model was optimal.
Quantifying Process Quality: The Role of Effective Organizational Learning in Software Evolution
Authors:   ,   Linnaeus University, Faculty of Technology, Department of computer science and media technology, Hönel Sebastian
Published: September 2023

Real-world software applications must constantly evolve to remain relevant. This evolution occurs when developing new applications or adapting existing ones to meet new requirements, make corrections, or incorporate future functionality. Traditional methods of software quality control involve software quality models and continuous code inspection tools. These measures focus on directly assessing the quality of the software. However, there is a strong correlation and causation between the quality of the development process and the resulting software product. Therefore, improving the development process indirectly improves the software product, too. To achieve this, effective learning from past processes is necessary, often embraced through post mortem organizational learning. While qualitative evaluation of large artifacts is common, smaller quantitative changes captured by application lifecycle management are often overlooked. In addition to software metrics, these smaller changes can reveal complex phenomena related to project culture and management. Leveraging these changes can help detect and address such complex issues. Software evolution was previously measured by the size of changes, but the lack of consensus on a reliable and versatile quantification method prevents its use as a dependable metric. Different size classifications fail to reliably describe the nature of evolution. While application lifecycle management data is rich, identifying which artifacts can model detrimental managerial practices remains uncertain. Approaches such as simulation modeling, discrete events simulation, or Bayesian networks have only limited ability to exploit continuous-time process models of such phenomena. Even worse, the accessibility and mechanistic insight into such gray- or black-box models are typically very low. To address these challenges, we suggest leveraging objectively captured digital artifacts from application lifecycle management, combined with qualitative analysis, for efficient organizational learning. A new language-independent metric is proposed to robustly capture the size of changes, significantly improving the accuracy of change nature determination. The classified changes are then used to explore, visualize, and suggest maintenance activities, enabling solid prediction of malpractice presence and -severity, even with limited data. Finally, parts of the automatic quantitative analysis are made accessible, potentially replacing expert-based qualitative analysis in parts.
Understanding Antecedent Components of Social Entrepreneurship in Relation to Entrepreneurship and Family Business
Authors: Vargas Zeledon Aaron A.
Published: September 2023

Background: This conceptual paper advance the understanding between the fields of entrepreneurship and family business to social entrepreneurship derived from studies which expose the existence of meaningful antecedent components moving closer to each other in the direction of social entrepreneurship.

Research design and methods: This paper presents a theoretical framework of five antecedent components that emerge as an active ground of practice and research based in a systematic literature review using different works published in scientific journal.  

Results: Social entrepreneurship within the last three decades, in spite of its rising acceptance, scholars are far from touching a defined consensus concerning their valuable impact. This paper sheds light on the understanding and offer a novel establishment of knowledge, which enlarges the social entrepreneurship domain. 

Conclusions: Yet little research elucidates the mechanisms addressing the antecedent components. In this aspect, examining the link that exist between entrepreneurship and family business will augment the social entrepreneurship domain enabling future research to consolidate the impact of the discipline.
Experimental Simulation of the Influence of Temperature on the Migration of Substances from Bottom Sediments
Authors: Zhezherya V. A. , Zhezherya T. P. , Linnik P. M. , Osipenko V. P.
Published: September 2023

The results of experimental investigations of the influence of water temperature on the migration of nutrients, organic matter, and metals from bottom sediments into the aquatic environment are discussed in the paper. It has been found that the increase in water temperature from 5°C to 15°C resulted in the increase in the concentration of inorganic nitrogen, inorganic and total phosphorus, and dissolved silicon respectively by a factor of 1.6, 1.1, 1.2, and 1.4. The increase in water temperature from 5°C to 25°C resulted in the increase in the content of these nutrients by a factor of 1.8, 5.8, 1.9, and 2.5. Water temperature increase influenced the contribution of nitrogen compounds to the total balance of inorganic nitrogen. A relative content of ammonium decreased, whereas the contribution of nitrite- and nitrate ions increased as a result of the process of nitrification. The concentration of readily oxidized organic matter and the total content of organic matter also increased almost by a factor of 1.6 with increasing water temperature from 5°C to 25°C. Under such conditions, the concentration of aluminum, manganese, and chromium increased by a factor of 1.9, 3.2, and 2.0. In this case, the content of iron and copper remained almost unchanged due to their occurrence in inaccessible fractions of bottom sediments. Artificial aeration at 25°C was responsible for an insignificant decrease in the concentration of inorganic nitrogen, inorganic and total phosphorus, dissolved organic matter, and also of dissolved aluminum, manganese, and chromium. It has been found that water temperature increase results in the migration of the studied chemical compounds from bottom sediments. However, this process is not as intensive as, for example, with a deficiency of dissolved oxygen and a decrease in pH and redox potential in the near-bottom layer of water.
Slippery surface with ternary coupled structures for improving lubricant-storage capacity
Authors: Zhai Ying , Lv Shuwei , Liu Qiao , Yang Xiaodong , Liu Xianli , Yang Zhuojuan , Mao Chunyu
Published: September 2023

A slippery surface has the capability to protect the substrate surface, which can prevent substrate corrosion in a harsh environment. However, existing slippery surfaces have the limitation of insufficient oil-locking capability for rough structures, which limits their practical application. To solve the aforementioned limitation, the authors developed a slippery surface with a good oil-locking capability. First, a wire-cutting machine tool was used to fabricate ternary coupled grooved structures on an aluminum (Al) substrate, which could increase the lubricant-storage capacity of the microstructures, and the substrate was named slippery porous surface with groove-textured aluminum (Slips-G-Al). Then, a surface durability test was performed involving lubricant shear, sandpaper wear and water impact. The chemical stability test involved acid, alkali, salt corrosion and weather resistance tests, which showed that Slips-G-Al had a good lubricant-storage capacity compared with the traditional Slips surface. In addition, the self-cleaning performance and the fog collection capability of Slips-G-Al were also studied. Finally, an electrochemical corrosion test of Slips-G-Al was carried out. The findings showed remarkable application prospects in the aerospace and shipbuilding fields.
Regarding the number of blades in the rotor of the wind turbine
Authors: M Shykhailov , V Kokhanevich
Published: September 2023

When developing a wind turbine, sooner or later the designer is faced with the problem of the number of blades. After all, the purpose of the wind turbine and its cost depends on this. The criteria were determined and an analysis was carried out regarding the appropriate number of blades in the rotor of the wind turbine.
A live-cell platform to isolate phenotypically defined subpopulations for spatial multi-omic profiling v1
Authors: O. Khatib Tala
Published: September 2023

Numerous techniques have been employed to deconstruct the heterogeneity observed in normal and diseased cellular populations, including single cell RNA sequencing, in situhybridization, and flow cytometry. While theseapproaches have revolutionized our understanding of heterogeneity, in isolation they cannot correlate phenotypic information within a physiologically relevant live-cell state with molecular profiles. This inability to integrate a live-cell phenotype - such as invasiveness, cell:cell interactions, and changes in spatial positioning - with multi-omic data creates a gap in understanding cellular heterogeneity. We sought to address this gap by employing lab technologies to design a detailed protocol, termed Spatiotemporal Genomic and Cellular Analysis (SaGA), for the precise imaging-based selection, isolation, and expansion of phenotypically distinct live cells. This protocol requires cells expressing a photoconvertible fluorescent protein and employs live cell confocal microscopy to photoconvert a user-defined single cell or set of cells displaying a phenotype of interest. The total populationis then extracted from its microenvironment, and the optically highlighted cells are isolated using fluorescence activated cell sorting. SaGA-isolated cells can then be subjected to multi-omics analysis or cellular propagation for in vitro or in vivo studies. This protocol can be applied to a variety of conditions, creating protocol flexibility for user-specific research interests. The SaGA technique can be accomplished in one workday by non specialists and results in a phenotypically defined cellular subpopulations for integration with multi-omics techniques. We envision this approach providing multi-dimensional datasets exploring the relationship between live cell phenotypes and multi-omic heterogeneity within normal and diseased cellular populations.
Sea Water - Blue Treasure v1
Authors: Barela Costa Willian
Published: September 2023

Sea water production for microalgae cultivation using the Blue Treasure supplier. 25 - 35 Salinity
DNA Isolation (Gel Clean-up) v2
Authors: iGEM NUS
Published: September 2023

2023 NUS-Singapore iGEM team followed this protocol to isolate the DNA fragments from the agarose gel after the gel electrophoresis.
Golden Gate Assembly v1
Authors: iGEM NUS
Published: September 2023

2023 NUS-Singapore iGEM team followed this protocol to assemble DNA oligos containing Golden Gate restriction sites with a plasmid backbone that contains the same restriction sites. The restriction enzymes utilised in this protocol are the Type IIS restriction enzymes, specifically BsaI. The use of Type IIS restriction enzymes ensures that there is no scar or extra sequence at the junctions between the assembled fragments.
Telecommunications Secrecy Violation in the Context of Russian Criminal Law: Current Problems and Prospects for Overcoming Them
Authors: Yurchenko I. A.
Published: September 2023

The paper is devoted to the controversial issues of criminal liability for violating the secrecy of correspondence, telephone conversations, postal, telegraph and other messages based on the analysis of Russian legislation, generalization of judicial practice and experience of foreign countries. The author explains the concept and content of communication secrecy, examines its correlation with other types of legally protected information, provides a criminal legal assessment of the dissemination of mutual correspondence without the consent of one of the addressees, and considers a sign of insignificance of the act in relation to encroachments on constitutional human rights. Telecommunications secrecy is defined as any information transmitted using wired, radio, optical or other electromagnetic systems, to which access is restricted in accordance with the Constitution of the Russian Federation, other regulatory legal and local acts. It is proposed to consolidate the provision that only a person who is not the addressee of negotiations, correspondence and other messages can bear criminal responsibility for violating the secrecy of communication. The rules of qualification of the violation of the secrecy of communication are formulated in conjunction with the crimes in the field of computer information, as well as with the illegal receipt and disclosure of information constituting a trade secret. It is noted that Part 2 of Article 138 of the Criminal Code of the Russian Federation should be supplemented with the provision listing qualifying signs of the use of information and telecommunication networks by a person and about unauthorized access to the critical infrastructure of the Russian Federation. The author criticizes the refusal of the courts to recognize the violation of the secrecy of communication as an insignificant act only because of the special significance of the object of criminal law protection. A rule is established to eliminate competing criminal law norms concerning exemption from liability for violating the secrecy of communication by applying the article of the Criminal Code of the Russian Federation, which is the most favourable for the person who committed the crime. In conclusion, the author proposes a new version of the article of the criminal law on violation of the secrecy of correspondence, telephone conversations and other telecommunication messages that provides for the composition of a crime with administrative prejudice.
The Development of Constitutionalism in Albania (1912-1938)
Authors: Alidemaj Avni , Haxhiu Sadik
Published: September 2023

The development of constitutionalism in Albania from 1912 until 1938 is characterized by the approval of four constitutional acts: Organic Statute of Albania in 1914, Statute of Lushnja in 1920, Basic Statute of the Republic of Albania in 1925, and Basic Statute of the Monarchy of Albania in 1928. These statutes have interrupted the tradition of applying Sharia Law in Albania, by applying models of the most advanced constitutions of the time, such as the monarchies and parliamentary republics of Western Europe and the United States. These acts have been approved in special political circumstances elaborated throughout the paper.
Enviado el (Submission Date): 02/07/2022Aceptado el (Acceptance Date): 14/09/2022
La Audiencia de Nueva Galicia vs. los alcaldes constitucionales. Un caso de infracción a la Constitución de Cádiz
Authors: Ramos Quiroz Francisco
Published: September 2023

La aplicación de la Constitución de Cádiz de 1812 presentó algunas complicaciones en los territorios de ultramar, pues el cambio en la naturaleza de algunas autoridades y el establecimiento de otras nuevas, hizo que se tuvieran que resolver algunas dudas sobre el margen de operación de las mismas, llegando inclusive algunos asuntos a resolverse con intervención de las autoridades centrales en España. El caso que nos ocupa en este trabajo tuvo lugar en 1821 en el territorio que hoy corresponde a México y guarda relación con una supuesta infracción a la Constitución que derivó en un conflicto entre la Audiencia de la Nueva Galicia y los alcaldes constitucionales de Guadalajara.
Enviado el (Submission Date): 13/08/2022
Aceptado el (Acceptance Date): 21/09/2022
Lo legal y lo legítimo: Notas en torno a la relación entre Otto Kirchheimer y Carl Schmitt
Authors: De Miguel Bárcena Josu
Published: September 2023

El presente trabajo pretende analizar la categoría de legitimidad constitucional a partir del debate mantenido entre Otto Kirchheimer y Carl Schmitt, discípulo y maestro durante la República de Weimar. Dicho debate nos permitirá, además, presentar la biografía intelectual y, sobre todo, la teoría del Estado y de la Constitución del joven Otto Kirchheimer, parcialmente olvidada, al público español. En el contexto de este análisis, consideramos interesante abordar igualmente la influencia de Carl Schmitt en la izquierda académica desde un punto de vista histórico y contemporáneo, teniendo en cuenta las contradicciones metodológicas del propio Kirchheimer, primer representante de lo que viene considerándose como “izquierda schmittiana”.
Fecha de envío / Submission Date: 22/10/2022Fecha de aceptación / Acceptance Date: 12/12/2022
El derecho administrativo del Estado en construcción: resignificaciones disciplinares en Brasil y España durante el siglo XIX
Authors: Guandalini Walter
Published: September 2023

Es de sentido común en la dogmática administrativista la importancia de la doctrina extranjera para la construcción teórica del derecho administrativo brasileño durante el siglo XIX. A pesar del indiscutible predominio de la doctrina francesa, otros países también tienen sus doctrinas consideradas por los administradores brasileños, con especial énfasis en la doctrina ibérica. Este artículo pretende analizar las representaciones que la doctrina administrativa brasileña del siglo XIX hace de la experiencia jurídica española, evaluando los factores que hacen posible esta traslación, los términos en que se desarrolla y los diversos usos y resignificaciones a los que esta experiencia es sometida por la doctrina jurídica brasileña. Al final, concluye que las dificultades similares enfrentadas por el Estado brasileño y el Estado español hacen que la doctrina española sea una referencia importante para la doctrina administrativa brasileña y desempeñe un papel relevante en el proceso de formación del derecho administrativo nacional.
Enviado el (Submission Date): 08/11/2022
Aceptado el (Acceptance Date): 3/01/2023
Joaquín Varela Suanzes y la construcción de la Historia Constitucional como disciplina
Authors: Fernández Sarasola Ignacio
Published: September 2023

Joaquín Varela no sólo fue autor de una extensa producción científica, sino que realizó una contribución decisiva al intento de convertir a la historia constitucional en una disciplina autónoma. A su parecer, la historia constitucional era un campo científico en el que confluían la historia contemporánea, el derecho constitucional, la historia del pensamiento político y la filosofía del derecho. Sus aportaciones metodológicas, así como la creación de revistas, editoriales y centros de investigación dedicados a la historia constitucional persiguieron ese objetivo de crear una nueva disciplina científica.

Enviado el (Submission Date): 12/03/2023

Aceptado el (Acceptance Date): 25/04/2023
Joaquín Varela y la historia del constitucionalismo: Mucho más que una cuestión de nombres y método
Authors: Álvarez Alonso Clara
Published: September 2023

Por méritos propios Joaquín Varela Suanzes-Carpegna es reconocido como uno de los fundadores de la Historia del constitucionalismo en España. Sus contribuciones al respecto han adquirido una proyección internacional y han sido elogiadas por los más conspicuos especialistas europeos e iberoamericanos. En este trabajo se quiere subrayar  la validez y originalidad de una producción construida sobre los presupuestos de la comparación y la contextualización, la apertura y colaboración con otras disciplinas jurídicas y extrajurídicas, la superación de los límites dogmáticos y temporales y los confesados fines de la materia. En especial en lo que referente  a la construcción de una historia constitucional europea que supere los rígidos esquemas de los nacionalismos, pero sin olvidar las características y peculiaridades de las  historias constitucionales propias.

Enviado el (Submission Date): 28/03/2023

Aceptado el (Acceptance Date): 27/04/2023
Joaquín Varela y la conversión de su vida en una pasión por la historia constitucional
Authors: Álvarez Álvarez Leonardo
Published: September 2023

El trabajo analiza algunos aspectos de la carrera profesional de Joaquín Varela, profesor de derecho constitucional de la Universidad de Oviedo. Su labor en las aulas de la Facultad de Derecho, su trayectoria en el Departamento de Derecho Público, y el periodo investigador en el final de su vida.
 

Enviado el (Submission Date): 28/03/2023
Aceptado el (Acceptance Date): 27/04/2023
Joaquín Varela, el mejor compañero de viaje.
Authors: Presno Linera Miguel Ángel
Published: September 2023

Este breve texto es una semblanza, personal y académica, del profesor Joaquín Varela Suanzes-Carpegna, Catedrático de Derecho constitucional de la Universidad de Oviedo, fallecido el 1 de febrero de 2018. El objetivo de estas páginas es destacar tanto su calidad humana como sus extraordinarias aportaciones a la Historia constitucional.
Enviado el / Submission date: 14/04/2023
Aceptado el / Acceptance Date: 29/05/2023
Análisis de los reforzadores docentes en didáctica científica gamificada con población adulta
Authors: Quintas-Hijós Alejandro , Martín-Bozas Fernando , Latre-Navarro Lorena
Published: September 2023

La gamificación se está constituyendo como foco de la revolución de la era digital en contextos educativos. Desde distintas teorías de la motivación, la gamificación se ha planteado como una propuesta para la mejora educativa. Dentro del contexto educativo de personas adultas con discapacidad intelectual en una organización sin ánimo de lucro, se desarrolló una investigación-acción focalizándose en la implementación gamificadora mediante la aplicación ClassDojo. Se formó a las profesoras (n = 4) de dicha institución en el método de la gamificación, e implementaron un programa experimental diseñado ad hoc durante 14 meses a personas adultas con discapacidad intelectual (n = 12). Se recogieron 8926 puntos donados, que implicaban reforzadores positivos. Mediante análisis correlacionales, se hallaron diferencias de interacción entre ciertas profesoras y algunos estudiantes, así como que el tipo de punto más frecuente fue el individual frente al grupal. Se destaca que existieron más interacciones de las tutoras con determinados participantes y que usar el ClassDojo favoreció la motivación. Los resultados animan a la comunidad educativa y científica a replicar este tipo de intervenciones en contextos similares. Además, sería interesante complementar los resultados hallados con otros de corte cualitativo para poder triangular los datos y, por tanto, las conclusiones de la presente investigación.
Análisis del discurso de las estrategias para la mejora de la convivencia escolar de las Comunidades Autónomas españolas
Authors: Azqueta Arantxa , Arbués Elena , Merino-Arribas Adoración
Published: September 2023

Los sistemas educativos del siglo XXI se enfrentan al desafío de promover los conocimientos, habilidades y actitudes que permitan a los jóvenes ser ciudadanos activos en las sociedades democráticas. En esta tarea, el clima de convivencia escolar es relevante porque contribuye a conformar la conciencia cívica. En esta investigación se emplea un análisis crítico-interpretativo, completado con un análisis lexicográfico del contenido de los documentos estratégicos relativos a la convivencia escolar de las 17 comunidades autónomas españolas. Para la visualización de los datos se utiliza el software Iramuteq. Los resultados ponen de manifiesto la importancia de poner el foco educativo en la convivencia escolar y en convertir los centros educativos en espacios participativos. También se recalca la puesta en marcha de proyectos para prevenir el acoso y la violencia. Asimismo, queda de manifiesto que la mejora de la convivencia escolar corresponde de manera compartida al profesorado, al alumnado y a las familias. Finalmente se concluye la relevancia de la mejora del clima escolar como elemento favorecedor de la motivación del alumno, de disminución de la violencia y de prevención del abandono escolar.