bluuebunny/crossref_metadata_2025 huggingface dataset:
Multi-century dynamics of the climate and carbon cycle under both high and net negative emissions scenarios
Authors: Koven Charles D. , Arora Vivek K. , Cadule Patricia , Fisher Rosie A. , Jones Chris D. , Lawrence David M. , Lewis Jared , Lindsay Keith , Mathesius Sabine , Meinshausen Malte , Mills Michael , Nicholls Zebedee , Sanderson Benjamin M. , Séférian Roland , Swart Neil C. , Wieder William R. , Zickfeld Kirsten
Published: May 2022

Abstract. Future climate projections from Earth system models
(ESMs) typically focus on the timescale of this century. We use a set of
five ESMs and one Earth system model of intermediate complexity (EMIC) to
explore the dynamics of the Earth's climate and carbon cycles under
contrasting emissions trajectories beyond this century to the year 2300.
The trajectories include a very-high-emissions, unmitigated fossil-fuel-driven scenario, as well as a mitigation scenario that diverges from the
first scenario after 2040 and features an “overshoot”, followed by a
decrease in atmospheric CO2 concentrations by means of large
net negative CO2 emissions. In both scenarios and for all models
considered here, the terrestrial system switches from being a net sink to
either a neutral state or a net source of carbon, though for different
reasons and centered in different geographic regions, depending on both the
model and the scenario. The ocean carbon system remains a sink, albeit
weakened by carbon cycle feedbacks, in all models under the high-emissions
scenario and switches from sink to source in the overshoot scenario. The
global mean temperature anomaly is generally proportional to cumulative
carbon emissions, with a deviation from proportionality in the overshoot
scenario that is governed by the zero emissions commitment. Additionally,
23rd century warming continues after the cessation of carbon emissions in
several models in the high-emissions scenario and in one model in the
overshoot scenario. While ocean carbon cycle responses qualitatively agree
in both globally integrated and zonal mean dynamics in both scenarios, the
land models qualitatively disagree in zonal mean dynamics, in the relative
roles of vegetation and soil in driving C fluxes, in the response of the
sink to CO2, and in the timing of the sink–source transition,
particularly in the high-emissions scenario. The lack of agreement among
land models on the mechanisms and geographic patterns of carbon cycle
feedbacks, alongside the potential for lagged physical climate dynamics to
cause warming long after CO2 concentrations have stabilized, points to
the possibility of surprises in the climate system beyond the 21st century
time horizon, even under relatively mitigated global warming scenarios,
which should be taken into consideration when setting global climate policy.
Cyclostratigraphy of the Middle to Upper Ordovician successions of the Armorican Massif (western France) using portable X-ray fluorescence
Authors: Sinnesael Matthias , Loi Alfredo , Dabard Marie-Pierre , Vandenbroucke Thijs R. A. , Claeys Philippe
Published: May 2022

Abstract. To expand traditional cyclostratigraphic numerical
methods beyond their common technical limitations and apply them to truly
deep-time archives, we need to reflect on the development of new approaches
to sedimentary archives that are not traditionally targeted for
cyclostratigraphic analysis but that frequently occur in the impoverished
deep-time record. Siliciclastic storm-dominated shelf environments are a
good example of such records. Our case study focuses on the Middle to Upper
Ordovician siliciclastic successions of the Armorican Massif (western
France) that are well-studied examples in terms of sedimentology and sequence
stratigraphy. In addition, these sections are protected geological heritage
due to the extraordinary quality of the outcrops. We therefore tested the
performance of non-destructive high-resolution (centimeter-scale) portable X-ray
fluorescence and natural gamma-ray analyses on an outcrop to obtain major
and trace element compositions. Despite the challenging outcrop conditions
in the tidal beach zone, our geochemical analyses provide useful information
regarding general lithology and several specific sedimentary features such
as the detection of paleo-placers or the discrimination between different
types of diagenetic concretions such as nodules. Secondly, these new
high-resolution data are used to experiment with the application of commonly
used numerical cyclostratigraphic techniques on this siliciclastic
storm-dominated shelf environment, a non-traditional sedimentological
setting for cyclostratigraphic analysis. In the parts of the section with a
relatively homogeneous lithology, spectral power analyses and bandpass
filtering hint towards a potential astronomical imprint of some sedimentary
cycles, but this needs further confirmation in the absence of more robust
independent age constraints.
The effect of spin polarization in DEER spectroscopy
Authors: Sweger Sarah R. , Denysenkov Vasyl P. , Maibaum Lutz , Prisner Thomas F. , Stoll Stefan
Published: May 2022

Abstract. Double electron-electron resonance (DEER) spectroscopy measures the distribution of distances between two electron spins in the nanometer range, often on doubly spin-labeled proteins, via the modulation of a refocused spin echo by the dipolar interaction between the spins. DEER is commonly conducted under conditions where the polarization of the spins is small. Here, we examine the DEER signal under conditions of high spin polarization, thermally obtainable at low temperatures and high magnetic fields, and show that the signal acquires a polarization-dependent out-of-phase component, both for the intra- and the inter-molecular contribution. For the latter, this corresponds to a phase shift of the spin echo that is linear in the pump pulse position. We derive a compact analytical form of this phase shift and show experimental measurements using monoradical and biradical nitroxides at several fields and temperatures. The effect highlights a novel aspect of the fundamental spin physics underlying DEER spectroscopy.
Modeling road surface potholes within the macroscopic flow framework
Authors: Fosu Gabriel Obed , Opong Joseph M. , Owusu Bright E. , Naandam Samuel M.
Published: May 2022

The continual wearing of road surfaces results to crack and holes called potholes. These road surface irregularities often elongate travel time. In this paper, a second-order macroscopic traffic model is therefore proposed to account for these road surface irregularities that affect the smooth flow of vehicular traffic. Though potholes do vary in shape and size, for simplicity the paper assumes that all potholes have conic resemblances. The impact of different sized potholes on driving is experimented using fundamental diagrams. Besides, the width of these holes, driver reaction time amid these irregularities also determine the intensity of the flow rate and vehicular speed. Moreover, a local cluster analysis is performed to determine the effect of a small disturbance on flow. The results revealed that the magnitude of amplification on a road surface with larger cracks is not as severe as roads with smaller size holes, except at minimal and jam density where all amplifications quickly fade out.
KEMUDAHAN DAN KEPASTIAN HUKUM PENGURUSAN IZIN USAHA SECARA ONLINE MELAUI PTSP DIKAITKAN DENGAN PERDA DKI JAKARTA No.12 TAHUN 2013 TENTANG PENYELENGGARAAN PELAYANAN TERPADU SATU PINTU
Authors: Latumahina Jeffry
Published: May 2022

Tujuan dari penelitian ini adalah untuk mengetahui apakah kemudahan dan kepastian hukum dalam pengurusan Izin Usaha Perdagangan secara online melalui Pusat Pelayanan Terpadu Terpadu Satu Pintu terkait dengan niat untuk mendirikan Pelayanan Terpadu Satu Pintu pada Pasal (3) Peraturan Daerah. Peraturan DKI Jakarta No.12 Tahun 2013 tentang Penyelenggaraan Pelayanan Terpadu Satu Pintu tercapai dengan baik. Metode pendekatan yang digunakan dalam penelitian ini adalah yuridis normatif atau disebut juga penelitian dokumen. Metode ini menggunakan data sekunder berupa hukum positif dan bahan pustaka seperti buku, karya ilmiah dan makalah seminar. Metode yuridis normatif ini digunakan untuk memahami realitas yang dikaitkan dengan peraturan perundang-undangan yang ada. Wawancara atau diskusi, yaitu mengadakan sesi tanya jawab atau berdiskusi untuk mendapatkan data primer secara langsung dalam lingkup pemanfaatan layanan Izin Usaha Perdagangan melalui Pelayanan Terpadu Satu Pintu dan hubungannya dengan peraturan daerah yang mengaturnya. Hasil penelitian ini menunjukkan bahwa kemudahan dan kepastian hukum untuk memperoleh Izin Usaha Perdagangan melalui Pelayanan Terpadu Satu Pintu terkait dengan niat untuk mendirikan Pelayanan Terpadu Satu Pintu dalam Pasal 3 Perda No.12 Tahun 2013 belum tercapai dengan baik.
DEVELOPMENT OF DIGITAL COMPETENCIES OF CIVIL SERVANTS IN THE REPUBLIC OF KAZAKHSTAN
Authors: Sergaliyeva R. , Bugubayeva R. , Tretyakova L. , Сергалиева Р.Т. , Бугубаева Р.О. , Третьякова Л.А.
Published: May 2022

The system of state administration is becoming more digital and convenient for citizens. In this regard, there are growing requirements for personnel who manage the digitalization processes, they must have a wide range of digital competencies. A modern civil servant who is responsible for the implementation of digital projects and the transfer of work to a digital environment must first of all have the skills to work in the digital world.The development of the unified information space of the civil service and the widespread introduction of e-government technologies place increased demands on the digital competencies of civil servants.When studying this research topic, the main strategic programs for the implementation of digitalization are considered and analyzed. In the course of the research, special attention is paid to the study of the current state of the electronic government of the republic, as well as an overview of upcoming projects on the introduction of digitalization.The result of the study is methodological recommendations on the transformation of competencies in the field of ICT, which have practical significance for improving the selection process of civil servants in the conditions of digitalization of the civil service. They will contribute to increasing the level of development of digital competencies of applicants for civil service positions.

Система государственного управления становится более цифровой и удобной для граждан. В связи с этим, растут требования к кадрам, которые управляют процессами цифровизации, они должны обладать широким спектром цифровых компетенций. Современный госслужащий, ответственный за реализацию цифровых проектов и перевод рабочих процессов в цифровую среду, должен прежде всего иметь навыки работы в цифровом мире.Развитие единого информационного пространства государственной службы и повсеместное внедрение технологий электронного правительства предъявляет повышенные требования к цифровым компетенциям государственных служащих.При изучении данной темы исследования использовались методы теоретического и сравнительного анализа, методы сравнения, сбор информации. Рассмотрены и проанализированы основные стратегические программы по внедрению цифровизации. В процессе исследования особое внимание уделено изучению текущего состояния электронного правительства республики, а также приведен обзор предстоящих проектов по внедрению цифровизации.Результатом исследования являются методические рекомендации по трансформации компетенций в области ИКТ, имеющие практическую значимость для совершенствования процесса отбора государственных служащих в условиях цифровизации государственной службы.Они будут способствовать повышению уровня развития цифровых компетенций претендентов на должности государственной службы.
PUBLIC ENTREPRENEURSHIP IN THE CONTEXT OF KAZAKHSTAN'S INNOVATION ECONOMY
Authors: Нурмухаметов Н.Н. , Темирова А.Б. , Нургалиева Ж.Е. , Тансыкбаева Г.О. , Nurmukhametov N. , Temirova A. , Nurgaliyeva Z. , Tansykbayeva G.
Published: May 2022

В статье рассмотрены основные условия характерные для развития государственного предпринимательства в рамках инновационной экономики, в контексте повышения экономической активности данной формы бизнеса как одной из стратегических направлений экономики страны.Определение значимости данной формы бизнеса рассматривается с различных его функциональных характеристик и предназначения, при этом особая роль государственного предпринимательства направлена на развитие социально-ориентированной модели рынка.Раскрытие экономической сущности государственного предпринимательства в контексте инновационной экономики требует переосмысление его роли и значения в условиях системного развития всех форм бизнеса.В современных условиях роль государственного предпринимательства возрастает в развитии новшеств, научно-технического потенциала национальных компании с целью определения результативности их влияние на социально-экономическое развитие страны в целом. Поэтому вопросы государственного бизнеса в контексте развития инновационной экономики в целом неизбежны на всех этапах развития шестого технологического уклада.В научной статье определены роль и задачи государственного предпринимательства в экономической реальности, с учетом определения конкурентоспособности государственного бизнеса в контексте цифровых реалии. Предложены меры и направления перспективы развития данной формы бизнеса в Казахстане.

The article considers the main conditions characteristic for the development of state entrepreneurship within the framework of innovation economy, in the context of increasing economic activity of this form of business as one of the strategic directions of the country's economy.Determination of the significance of this form of business is considered from its various functional characteristics and purpose, with a special role of state entrepreneurship aimed at the development of a socially-oriented market model.Disclosure of the economic essence of state entrepreneurship in the context of innovation economy requires rethinking its role and importance in the context of systemic development of all forms of business.In modern conditions the role of state entrepreneurship increases in the development of innovations, scientific and technological potential of national companies in order to determine the effectiveness of their impact on the socio-economic development of the country as a whole. Therefore, the issues of state business in the context of development of the innovation economy as a whole are inevitable at all stages of development of the sixth technological mode.The scientific article defines the role and tasks of state entrepreneurship in the economic reality, taking into account the definition of the competitiveness of state business in the context of digital realities. Proposed measures and directions for the prospects of development of this form of business in Kazakhstan
Анализ инновационной активности регионов Центрального Казахстана, необходимый для оценки конкурентоспособности
Authors: Викуленко Ю.Р. , Иванов А.В. , Кокушева Г.Я. , Vikulenko Yu. , Ivanov A. , Kokusheva G.
Published: May 2022

В настоящее время долгосрочный конкурентный успех предприятия зависит от его инновационной деятельности, основной целью которого является определение рыночной ниши и занятие лидирующей позиции. В данной работе мы исследуем феномен инновационного предпринимательства, явление которого является одним из основных факторов устойчивого экономического развития и национальной жизни, и характеризуется интеграцией отношений и активным поиском новых парадигм, чтобы справиться с постоянными изменениями эпохи глобализации. Проблема выявления таких связей была исследована и решена путем применения сложного показателя, как анализ структурной динамики, который показал, что при его применении для оценки экономической конкурентоспособности региона, регионы с крупными агломерациями и динамичным развитием занимают лидирующие позиции, что дает повод признать важность организационной формы этого экономического пространства для формирования критической массы конкурентоспособных отраслей. С помощью метода структурно-динамического анализа к региональной конкурентоспособности результатом исследования явилось определение отраслевых профилей региональной конкурентоспособности на основе показателей промышленного производства, что позволило определить как профиль конкурентоспособности региона, так и количество основных отраслей специализации и количество отраслей с динамикой лучше, чем в среднем по стране.

At present, the long-term competitive success of an enterprise depends on its innovative activities, the main purpose of which is to define a market niche and take a leading position. In this paper we investigate the phenomenon of innovative entrepreneurship, the phenomenon of which is one of the main factors of sustainable economic development and national life, and is characterized by the integration of relationships and the active search for new paradigms to cope with the constant changes of the era of globalization. The problem of identifying such links was investigated and solved by applying a complex indicator as a structural dynamics analysis, which showed that when it is applied to assess the economic competitiveness of a region, regions with large agglomerations and dynamic development take the leading positions, which gives reason to recognize the importance of the organizational form of this economic space for the formation of a critical mass of competitive industries. Using the method of structural-dynamic analysis to regional competitiveness, the result of the study was the determination of sectoral profiles of regional competitiveness on the basis of industrial production indicators, which allowed to determine both the profile of regional competitiveness and the number of major industries of specialization and the number of industries with dynamics better than the national average.
BASIS OF ECONOMIC DEVELOPMENT OF ENTERPRISES OF KAZAKHSTAN IN THE REALIZATION OF COMPETITIVE ADVANTAGES
Authors: Ставбуник Е.А. , Жидкоблинова О.В. , Мукатай А. , Джазыкбаева Б.К. , Stavbunik Y. , Zhidkoblinova O. , Mukatay A. , Jazykbayeva B.
Published: May 2022

В данной статье отмечается, что на экономику Республики Казахстан оказало воздействие мировой пандемии коронавируса. По прежнему существует неопределенность относительно будущего экономического роста, доступности капитала, а также стоимости капитала, что может негативно повлиять на реализацию конкурентных преимуществ предприятий.Особое место занимает проблема повышения эффективности использования производственных мощностей предприятия. Возникает необходимость в совершенствовании механизма повышения эффективности использования основного капитала предприятий в целях обеспечения снижения издер­жек производства и роста производительности труда.Исследование факторов, влияющих на использование основных фондов, позволит выявить направления повышения эффективности использования основных фондов.Авторами приведены показатели валового внутреннего продукта методом доходов, технического состояния основного капитала промышленных предприятий Республики Казахстан, инвестиции в основной капитал, динамика прибыли промышленных предприятий за последние годы.Отмечается, что амортизация в основной своей части практически перестала нести выполнять функции и роль главного источника финансового обеспечения воспроизводственных процессов элементов основного капитала, в лучшем случае обслуживая текущие потребности реновации. С помощью целенаправленной современной государственной политики необходимо создание предпосылок экономического роста.

This article notes that the economy of the Republic of Kazakhstan was affected by the global coronavirus pandemic. Despite some indicators of economic recovery, there is still uncertainty about future economic growth, the availability of capital, and the cost of capital, which could negatively affect the realization of the competitive advantages of domestic enterprises. It is highlighted that the problem of increasing the efficiency of the use of fixed assets and production capacities of the enterprise occupies a central place. Having a clear understanding of the role of each element of fixed assets in the production process, their physical and moral deterioration, factors affecting the use of fixed assets, it is possible to identify methods, directions by which the efficiency of using fixed assets and production capacities of an enterprise is increased, providing a reduction in production costs and an increase in labor productivity. The indicators of gross domestic product by the method of income, the technical condition of the fixed capital of industrial enterprises of the Republic of Kazakhstan, investments in fixed capital, the dynamics of profits of industrial enterprises are given. It is noted that depreciation in its main part has practically ceased to perform the functions and role of the main source of financial support for the reproduction processes of fixed capital elements, at best serving the current needs of renovation.
INCREASE THE OIL PRICES AND THE EFFECT OF REAL EXCHANGE RATE ON REGIONAL ECONOMIC GROWTH: THE CASE OF KAZAKHSTAN
Authors: Bolganbayev A. , Myrzabekkyzy K. , Baimaganbetov S. , Kelesbayev D. , Болганбаев А.Д. , Мырзабеккызы К. , Баймаганбетов С.Т. , Келесбаев Д.Н.
Published: May 2022

An increase of oil prices will affect the Kazakhstan economy in various ways. However, in the world each country has regions with its economic structure, level of development, and system. There are differences between regions in terms of economic, physical, and social conditions, and these differences can affect their levels of economic development. This study examines 14 regions of Kazakhstan and two big cities with special status and the relations between Gross Regional Product (GRP) per Capita, Brent type crude oil prices, and real exchange rate. In this article: to study the short-term impact of changes in oil prices on regional growth in Kazakhstan and the real exchange rate, the ADF Unit Root Test and Granger causality test were used. The results showed that Aktobe, Almaty, West Kazakhstan, and Pavlodar Regions are affected by oil prices, while the oil price is not a Granger cause for other regions. In addition, it has been concluded that while the real exchange affects Akmola, Karaganda, Kyzylorda, and East Kazakhstan regions, it is not a Granger reason for the other regions.This study investigated the reasons for the development of the Kazakhstan regions. Two variables were included in the model as external factors. These are oil prices and real exchange rates. It is also tested whether the real exchange rate is the Granger cause of the development of the regions.

В каждой стране есть регионы со своей экономической структурой, уровнем развития и систематичностью. Между регионами существуют различия в экономических, физических и социальных условиях, и эти различия могут повлиять на их уровень экономического развития. В данной работе исследуются 14 регионов Казахстана и 2 города республиканского значения, а также отношения между 3 переменными валовым региональным продуктом (ВРП) на душу населения, ценами на сырую нефть марки Брент и реального обменного курс. Для изучения краткосрочного влияния изменения цен на нефть на региональный рост в Казахстане и на реальный обменный курс были использованы тест единичного корня ADF и тест причинно-следственных связей Грейнджера. Результаты показали, что Актюбинская, Алматинская, Западно-Казахстанская и Павлодарская области подвержены влиянию цен на нефть, в то время как цена на нефть не является причиной изменения (Грейнджера) для других регионов. Кроме того, был сделан вывод, что хотя реальный обмен курса валют затрагивает Акмолинскую, Карагандинскую, Кызылординскую и Восточно-Казахстанскую области, он не является причиной изменения (Грейнджера) для других регионов.
How to practice the return and +1s in women‘s professional tennis
Authors: Born Philipp , Vogt Tobias
Published: May 2022

The aim of this article is to present stroke placements of the return, the 3rd stroke and 4th stroke in professional women’s tennis. Based on recent scientific insights (Born et al., 2021), training recommendations as well as practice patterns will be derived from these results.For returns, training recommendations include aiming to the middle zones and longer than the service line. For 3rd strokes, it is recommended to e.g., train hitting into the c-zones, whereas for 4th strokes this is e.g., hitting more frequently to the backhand or, respectively, the weaker side of the opponent. Practice patterns are exemplified for each stroke.
Make it fun! A new proposal to organize tournaments for 12&U
Authors: Botella Hector
Published: May 2022

The main goal of this article is to expose a comprehensive overview of mental health concerns in young athletes while playing in competitions and to provide a list of new different initiatives to organize tournaments for 12&U,  with the aim of finding higher satisfaction and fewer levels of stress while performing.
Unruh effect of multiparticle states and black hole radiation
Authors: Wang Jianyu ,   Department of Astronomy, School of Physical Sciences, University of Science and Technology of China, Hefei 230026, China,   CAS Key Laboratory for Researches in Galaxies and Cosmology, University of Science and Technology of China, Hefei 230026, China,   School of Astronomy and Space Science, University of Science and Technology of China, Hefei 230026, China
Published: May 2022

In this study, we investigated the field under the Unruh effect. The energy and entanglement properties of the single-mode \begin{document}$q$\end{document}-particle states were discussed. We found that in the non-inertial reference frame \begin{document}$|q, 0\rangle_\alpha$\end{document} states exhibit a similar energy spectrum to vacuum \begin{document}$|0, 0\rangle_\alpha$\end{document}, but with different entanglement properties. With respect to an application, we proposed a black hole radiation model, assuming that states near the horizon are constructed via \begin{document}$q$\end{document}-particle states. We calculated the evolution of the entanglement entropy of radiation and proved that our model can reproduce the Page curve. Hence, this can be considered as an indication solution of the black hole information paradox.
Productividad, crecimiento y estancamiento de la economía mexicana (1950-2015)
Authors: Hernández Laos Enrique
Published: May 2022

El presente libro hace una relevante aportación al análisis del crecimiento económico de México en un contexto de largo plazo (1950-2015). A partir de un acucioso estudio de la bibliografía existente, el libro examina, preferentemente de manera cuantitativa, la trayectoria de la productividad multifactorial agregada y sectorial de México, la acumulación de capital fijo y humano, el desarrollo tecnológico, las tendencias demográficas y las condiciones de operación de los mercados de factores, y plantea hipótesis de interés para entender la precaria ruta que el crecimiento de la economía nacional registra desde hace varias décadas y que, en diversos años, ha revestido un carácter de franco estancamiento en términos per cápita.
Nonlinear optical response of D-π-A chromophores based on benzoxazin: quantum modification of π‑spacer
Authors: Azaid A. , Abram T. , Kacimi R. , Raftani M. , Khaddam Y. , Nebbach D. , Sbai A. , Lakhlifi T. , Bouachrine M.
Published: May 2022

In this research article, four chromophores based on benzoxazine as the electron donor and tricyanovinyl dihydrofuran (TCF) as the electron acceptor have been designed to investigate the nonlinear optical (NLO) response. The geometric and electronic structures, absorption spectra, NBO analysis, and nonlinear optical response have been calculated by employing density functional theory (DFT) at PBEPBE/6-31G (d,p). The new design of chromophores has been proposed by the structural modification of π-spacers/conjugated systems. The DFT and TD−DFT computations at CAM−B3LYP/6−31G (d,p) have been performed to shed light on the influences of structural modification on the NLO properties. The absorption wavelength in different organic solvents, polarizability (α), and hyperpolarizability (β) are all determined. A strong NLO response indicates that this family of organic compounds with a D-π-A structure exhibits large first hyperpolarizability βtot values, these values are much greater than ones of urea. This theoretical model may be used to design other chromophores for usage in electro-optics.
Synthesis and anticancer properties of 3-furan-2-yl-2-(4-furan/thiophen-2-ylthiazol-2-yl)acrylonitrile derivatives
Authors: Matiichuk Yulia , Horak Yuriy , Chaban Taras , Chaban Ihor , Matiychuk Vasyl
Published: May 2022

By the reaction of (4-furan-2-yl-thiazol-2-yl)- 3a and (4-thiophen-2-yl-thiazol-2-yl)- 3b acetonitriles with furfural 4 and 5-arylfurfyrals 5a-g 3-furan-2-yl-2-(4-furan/thiophen-2-ylthiazol-2-yl)acrylonitrile derivatives 6a-i were obtained. Anticancer activity screening was carried out within the framework of Developmental Therapeutic Program of the National Cancer Institute's (DTP, NCI, Bethesda, Maryland, USA). It was found out that (2E)-3-(2-furyl)-2-[4-(2-furyl)-1,3-thiazol-2-yl]acrylonitrile (6a) and 2-(4-thiophen-2-yl-thiazol-2-yl)-acrylonitriles 6h,i possessed low activity and 2-(4-furan-2-yl-thiazol-2-yl)acrylonitrile derivatives 6b-g showed moderate action. Compounds 6b-g were sensitive to cell lines of MDA-MB-468 and T-47D Breast Cancer. In this case cytotoxic effect was observed with a range of GP = -38.24 – 1.28%.
Análisis del régimen impositivo simplificado ecuatoriano: microempresas de Pichincha 2019-2020
Authors: Ortega Naranjo William , Jaramillo Bayas Carolina , Chulde Malquin Henry , Lojano Lojano Juan
Published: May 2022

La recaudación de impuestos en el Ecuador viene a formar parte fundamental en el Presupuesto General del Estado. En el caso de las microempresas o pequeñas empresas el estado requiere de su contribución para poder seguir fomentando la cultura tributaria en el país, y es ahí donde se ejecuta el Régimen Impositivo Simplificado Ecuatoriano. La investigación tiene como objetivo analizar la variación que tuvo la recaudación del este impuesto según dicho régimen en el año 2019-2020. La investigación es descriptiva de carácter cualitativo en el cual se analizan los resultados obtenidos por los instrumentos de investigación y de carácter cuantitativo porque fue posible hacer una medición sobre su impacto. Mediante la información obtenida de los años de estudio se determinó la afectación económica negativa con una reducción del 9% en el año 2020 en relación con el año 2019. Una de sus causas fue la emergencia sanitaria a nivel mundial por lo cual muchos emprendimientos tuvieron que cerrar actividades de forma permanente; con esta disminución el estado se ve afectado por la falta de ingresos para el presupuesto que destina. Es importante capacitar y fomentar la cultura tributaria en los contribuyentes para recaudar de mejor manera los impuestos.
Estrés financiero en las pequeñas y medianas empresas en Quito, Ecuador
Authors: Ortega Naranjo William , De la Torre José , Pérez Manosalvas Héctor , Caicedo Linger Edgar
Published: May 2022

En un mundo globalizado las empresas necesitan decisiones acertadas que les permita reducir el estrés financiero al pertenecer a una economía volátil. El presente artículo tiene como objetivo medir el nivel y conocer las causas del estrés financiero de quienes son dueños o administradores de las pequeñas y medianas empresas en Quito, Ecuador. La investigación es de tipo descriptiva, bibliográfica-documental. Se aplicaron encuestas con escala Likert a personeros de las 379 empresas determinadas en la muestra y los datos fueron procesados en el programa IBM SPSS 24. Los resultados indican que el 82,32% de esta clase de empresas tiene un nivel de estrés financiero alto y esto obedece al temor de pérdidas financieras y el endeudamiento que mantienen. El estrés financiero se genera en mayor nivel en la población con rango de edad 20 a 41 años, en tanto que quienes tienen más de 41 años es medio y bajo. Las pequeñas empresas y el sector comercial son quienes se ven más afectados por el estrés financiero, lo que denota la fragilidad de este sector. Los indicadores financieros son una alternativa para tener una visión sobre las empresas y tomar decisiones oportunas para evitar el estrés financiero.
Ética y bioética en la práctica profesional
Authors: Pinilla Forero José
Published: May 2022

Para impactar las necesidades y entornos culturales es necesario manejar teórica y prácticamente la conceptualización relacionada con la ética, la bioética y los códigos deontológicos que regulan la práctica social de las profesiones. La ética general ha sido reconocida en su evolución de muchos años. Por su parte, la bioética es un conocimiento relativamente reciente y forma parte de una corriente internacional que inició en las últimas décadas. En ese sentido, el objetivo de este artículo es ofrecer un panorama sobre los códigos de ética y bioética, así como su importancia en el ámbito profesional.
The role of preprocedural mouth rinse application in decreasing COVID-19 transmission in Dental Care Settings: A mini-review
Authors: Sanaz Gholami Toghchi  , Nozhan Azimi  , Nahal Azimi
Published: May 2022

The COVID-19 virus present in saliva and respiratory droplets is a possible high-risk source of viral transmission in health care settings. Dental practitioners and dentists in particular are highly susceptible to virus acquisition from their source patients. Mouthwashes before dental examination and procedures may be one possible solution to decrease the viral burden in the mouth, hence reducing transmission probability. Application of hydrogen peroxide, cetylpyridinium chloride, povidone-iodine, and chlorhexidine have been proposed to achieve this target. This paper aims to investigate for evidence in the literature for a decrease in the viral burden following preprocedural application of different mouthwashes.
Genetic variability and inter-relationship between cooking time and some physico-chemical characteristics in pigeon pea (Cajanus cajan (l.) Millsp.) genotypes
Authors: Innocent Ezeorah Ezeaku  , Hakeem Ajeigbe
Published: May 2022

Twenty two pigeon pea (Cajanus cajan) genotypes were evaluated for their physicochemical and cooking quality traits. There were significant differences among genotypes for seed weight (8.83-12.47 g), water absorption capacity (13.00-28.67 ml), seed hardness (17.00-21.70 Nm2), swelling ration (2.067-2.973 ml) and cooking time (66.67-86.67 min). Cooking time showed significant correlation with water absorption capacity and swelling ration indicating that these traits may be involved in controlling cooking time. The results of this study indicates that it is possible to develop cultivars with faster cooking time among pigeon pea cultivars through improvement in their water absorption capacity and swelling ration. Cultivar, ICPL 87091 which took lowest time to cook should be further investigated to determine additional qualities that could have influenced its cooking time.
TMX, Organizational Citizenship Behavior Dengan Kontrak Psikologis Sebagai Variabel Mediasi
Authors: Prakoso Benedictus , Gunawan D. Agus
Published: May 2022

Penelitian ini bertujuan menguji hubungan antara team member exchange (TMX), kontrak psikologis,dan organizational citizenship behavior (OCB). Sampel dalam penelitian ini berjumlah 75 karyawan, terdiri dari wanita 44 orang dan pria 31 orang. Teknik analisis menggunakan analisis jalur dengan program AMOS 18, hasil penelitian membuktikan terdapat pengaruh signifikan TMX terhadap OCB dan kontrak psikologi terhadap OCB. Hasil perhitungan efek langsung TMX ke OCB masih lebih besar dibandingkan dengan kontrak psikologis sebagai mediasi.
Merevitalisasi Penggunaan Bahasa Inggris pada Satuan Pendidikan
Authors: Heri Pranoto Yohanes , Inharjanto Anselmus
Published: May 2022

This study aims at revitalizing the role of the English language in education, where it becomes the house of the students for most time in their lives. When something wrong occurs and goes on the paradigm conformation of this revitalization, shifting assumption should become one of the efforts and be strived by one most element who takes main responsibility on education itself – teacher. This study explores empirically and theoritically the teachers’ paradigm on the use of English language in the real classroom. The participants were the teachers from private schools in Lahat and Bengkulu joining a workshop due to Hari Studi Guru conducted by the foundations. The workshop results were reflected and interpreted by the involvement of a related-literature review from previous researchers and experts - journal articles and scientific books.
Pengembangan Industri Pupuk BAOC Ribon Atom I melalui Penyempurnaan TTG Teknologi Produksi
Authors: Epriliati Indah , Kuswardani Indah , Armunanto Bram
Published: May 2022

Abstract. An effort to produce standardized liquid organic fertilizer initially established by a small-scale enterprise was taken by the improvement of production technology. This study aimed to obtain a production line machines of the liquid fertilizer and to determine a standard operational method. The designs included fermentor, hopper, mixer, and autofilling machine; and testing the new fermentor performance as the critical point. The product obtained can preserve the excellence of the initial Ribon Atom 1 characteristics (old fermentor).

 

[Abstrak. Upaya untuk memproduksi pupuk organik cair terstandar yang awalnya diterapkan oleh UMKM dilakukan melalui perbaikan teknologi produksi. Riset ini bertujuan untuk mendapat mesin-mesin jalur produksi pupuk organik cair dan menentukan metode standar operasinya. Rancang bangun meliputi fermentor, hopper, mixer, autofilling dalam pembotolan; dan melakukan uji kinerja fermentor baru sebagai titik kritis. Produk yang diperoleh dapat mempertahankan keunggulan karakteristik Ribon Atom 1 yang semula (fermentor lama).]
MICRORGANISMOS CAUSADORES DE MASTITE EM REBANHOS LEITEIROS DA REGIÃO DE SÃO JOÃO DEL-REI E A QUALIDADE DO LEITE
Authors: Leite Ana Luiza de Oliveira , Coura Fernanda Morcatti , Paciulli Sônia de Oliveira Duque
Published: May 2022

A mastite é a doença mais importante em rebanhos leiteiros, acarretando prejuízos sanitários e econômicos aos produtores e à indústria. O estudo objetivou identificar os agentes causadores de mastite, avaliar a relação entre a sua ocorrência e a qualidade do leite de 30 propriedades da região de São João del-Rei/MG. Efetuou-se uma comparação à média da contagem de células somáticas com os parâmetros estabelecidos pela legislação e também foi verificada qual a interferência dos agentes causadores de mastite no rebanho com CCS. Além disso, avaliou-se a suscetibilidade de isolados de S. aureus e de S. agalactiae a 7 antimicrobianos. De acordo com os resultados, a presença do patógeno S. agalactiae é responsável por importantes alterações na CCS dos animais em relação aos outros patógenos, além de provavelmente contribuir negativamente para a qualidade do leite. Também se verificou um acentuado nível de resistência para o agente S. aureus, sendo os antibióticos menos eficazes contra os agentes Penicilina, Enrofloxacina e Neomicina, e o de melhor eficácia, Cefalexina. Para o S. agalactiae, os antimicrobianos mais resistentes foram Ampicilina e Cefalexina, sendo o ácido Clavulânico+amoxicilina o mais eficiente. Os resultados obtidos demonstram a necessidade e a importância do controle da mastite, visando minimizar as perdas de produção leiteira e melhorar os índices econômicos, assim como elevar a sanidade do rebanho e a qualidade da matéria-prima ofertada às indústrias.
EXPERIÊNCIA DE ADAPTAÇÃO DOS CALOUROS E A SAÚDE MENTAL DOS ESTUDANTES UNIVERSITÁRIOS: UM PARÂMETRO PRÉ-PANDÊMICO
Authors: Sousa Vanessa dos Santos , Farias Vanessa Ruana Amorim , Casarin Roberson Geovani
Published: May 2022

O presente estudo buscou investigar a experiência de adaptação dos calouros e a situação da saúde mental dos estudantes da Universidade Federal do Sul e Sudeste do Pará (Unifesspa). Para o levantamento sobre adaptação, participaram 91 estudantes de sete cursos, que estivessem cursando até o segundo período. Os resultados indicaram que possuir uma rede de apoio, manter boa relação com os pares e professores, além de uma significativa relação e cooperação com a turma contribuem para a adaptação. Dentre os fatores que dificultam o processo de adaptação estão sair da “residência mãe” e não se inserir no curso de primeira opção do vestibular. No que tange à situação da saúde mental de estudantes universitários, participaram 75 discentes distribuídos por sete cursos, que cursavam entre o quarto e o sétimo períodos. De acordo com os resultados, a maioria considera prioridade cuidar da saúde mental, no entanto foi possível notar que dificuldades relevantes impactam o desempenho acadêmico, assim como a vivência externa a universidade.
The Intersection of the Rule in Yerkey v Jones and Contemporary Anti-Discrimination Law in Australia – Can the ‘Special Wives’ Equity Survive?
Authors: Yin Kenneth , Naser Mostafa Mahmud
Published: May 2022

The High Court in Yerkey v Jones considered the enforceability of a guarantee provided by a married woman to secure her husband’s debts. Dixon J said that although the relationship of husband and wife did not give rise to a presumption of undue influence, the law had never been divested completely of ‘the equitable presumption of an invalidating tendency’. Dixon J’s formulation was essentially adopted by the majority justices in Garcia v National Australia Bank and their judgment thus represents the definitive endorsement of Dixon J’s view. Kirby J on the other hand rejected ‘the stereotype underlying Yerkey’, which he described as evidence of an ‘unprincipled discriminatory category’.

This article advances the argument that the majority’s view of wives was stereotypical and accordingly would be inconsistent with the principles of contemporary sex discrimination laws which prohibit discrimination based on the assumption of stereotypical views. This inconsistency will be explored by first discussing the propositions that underpinned the Yerkey and Garcia, and by comparing them with the treatment of those propositions in contemporary discrimination law.
Asynchronous Learning Initiatives: Case Study during COVID-19
Authors: Azeem Muhammad , Asghar Sehar , Lodhi Rab Nawaz , Hussain Amjad , Ahmad Ayyaz , Naz Farkhanda
Published: May 2022

Disruption to education and the havoc of a health crisis have been common trends found in every region of the globe as a consequence of the COVID-19 epidemic. This pandemic has interrupted educational activities worldwide. Countries have taken significant measures to continue education via asynchronous learning. Cases were selected to explore “how have countries taken initiatives in switching from synchronous learning to asynchronous learning during the critical time of the COVID-19 pandemic?” Secondary data was collected from existing literature and published reports. Yin explanatory, embedded case study design was employed and thematic analysis was carried out using NVIVO 12. It is observed that 95 percent of countries of the world have taken steps toward asynchronous learning in the emergency period for each level of education, and some common emerging tools for asynchronous learning are also identified in the study. This study was first conducted to investigate the trend of countries in a state of emergency providing a continuation of educational activities utilising their available resources. The study is believed to be helpful for countries of different regions wanting to modify the existing asynchronous learning infrastructure. Post emergency measures may be considered for further studies.
Rezension von: Beuckers, Klaus Gereon (Hrsg.), Die mittelalterlichen Wandmalereien zwischen Rhein, Neckar und Enz
Authors: Setzler Sibylle , Beuckers Klaus Gereon
Published: May 2022

Klaus Gereon Beuckers (Hrsg.): Die mittelalterlichen Wandmalereien zwischen Rhein, Neckar und Enz. (Heimatverein Kraichgau e. V. Sonderveröffentlichung Nr. 35). Verlag regionalkultur Ubstadt-Weiher 2011. 512 Seiten mit 551 farbigen Abbildungen. Fester Einband € 79,–. ISBN 978-3-89735-669-6
Rezension von: Lorenz, Sönke u.a. (Hrsg.), Die Universität Tübingen zwischen Scholastik und Humanismus
Authors: Schweizer Günther , Lorenz Sönke
Published: May 2022

Sönke Lorenz, Ulrich Köpf, Joseph S. Freedman und Dieter R. Bauer (Hrsg.): Die Universität Tübingen zwischen Scholastik und Humanismus. In Verbindung mit dem Institut für Geschichtliche Landeskunde und Historische Hilfswissenschaften der Universität Tübingen und der Akademie der Diözese Rottenburg-Stuttgart. (Tübinger Bausteine zur Landesgeschichte, Band 20). Thorbecke Verlag Ostfildern 2012. 503 Seiten mit einigen Abbildungen. Pappband € 39,90. ISBN 978-3-7995-5520-3
Rezension von: Bumiller, Casimir; Rüth, Bernhard; Weber, Edwin Ernst (Hrsg.), Mäzene, Sammler, Chronisten
Authors: Waibel Raimund , Bumiller Casimir , Rüth Bernhard , Weber Edwin Ernst
Published: May 2022

Casimir Bumiller, Bernhard Rüth und Edwin Ernst Weber (Hrsg.) Mäzene, Sammler, Chronisten. Die Grafen von Zimmern und dieKultur des schwäbischen Adels. Chr. Belser Verlag Stuttgart 2011. 353 Seiten mit zahlreichen Abbildungen. Gebunden € 39,95. ISBN 978-3-7630-2625-8
Rezension von: Ulmer, Martin, Antisemitismus in Stuttgart 1871–1933
Authors: Setzler Wilfried , Ulmer Martin
Published: May 2022

Martin Ulmer: Antisemitismus in Stuttgart 1871–1933. Studien zum öffentlichen Diskurs und Alltag. Metropol-Verlag Berlin 2011. 478 Seiten mit 12 Abbildungen. Pappband € 28,–. ISBN 978-3-940938-82-4
Rezension von: Fritz, Eberhard, Diener und Beamte am württembergischen Hof 1806–1918
Authors: Schreiber Klaus , Fritz Eberhard
Published: May 2022

Eberhard Fritz: Diener und Beamte am württembergischen Hof 1806 – 1918. Ein biografisches Verzeichnis. Cardamina-Verlag Breuel Plaidt 2012. XII, 388 Seiten. Gebunden € 35,–. ISBN 978-3-86424-065-2
Rezension von: Drecoll, Volker Henning; Baur, Juliane; Schöllkopf, Wolfgang (Hrsg.), Stiftsköpfe
Authors: Schreiber Klaus , Drecoll Volker Henning , Baur Juliane , Schöllkopf Wolfgang
Published: May 2022

Volker Henning Drecoll, Juliane Baur und Wolfgang Schöllkopf (Hrsg.): Stiftsköpfe. Mohr Siebeck Verlag Tübingen 2012. XI, 400 Seiten. Fadengeheftete Broschur € 24,00. ISBN 978-3-16-152231-4
Ultrasound imaging of anatomical variations of humeral insertions of the subscapular muscle
Authors: Snoeck Thyl , Selfslagh Lucie , Paillaugue Frederic , Provyn Steven
Published: May 2022

Aims: The purpose of this study was to highlight the variations of the humeral insertion of the muscle in vivo, by means of an ultrasound (US) device to depict anatomical variations that could lead to instability of the scapulohumeral complex. Methods: This prospective study (IRB approval) brings a dynamic imaging of the anatomical variation by US exploration of 193 shoulders to confirm MRI and dissection approaches.

Results: The results confirm the previous classification of two different classes of organization. 20% with a non-fibrous bridge over the intertubercular groove (type I and II combined) and 80% with a fibrous bridge over the tendon of the long head of the bicipital tendon muscle (type III and IV combined). Furthermore, statistical analysis (Fisher and Chi square test with a threshold of 95%) showed that this variation is not related to gender, side or laterality.

Conclusion: This study shows the same results as obtained by dissection or MRI, meaning that this non-radiating, easy to perform technique can be used as a first approach in a dynamic clinical examination to detect anatomical variations of the subscapular muscle.
Supernumerary first dorsal interosseous muscle of the hand
Authors: Chernev Alexandra , Chernev Ivan
Published: May 2022

No Abstract