bluuebunny/crossref_metadata_2025 huggingface dataset:
Bridging Human Expertise and AI
Authors: Gimmelberg Dmitrii , Glowacka Marta , Belinskiy Alexey , Korotkii Sergei , Artamov Valentin , Ludviga Iveta
Published: February 2025

This study investigates the role of large language models (LLMs) in retail investors (RIs) decision-making processes from the perspective of the Theory of Planned Behaviour (TPB). It explores whether LLMs can replace or change the role of financial experts and whether introducing LLMs may lead to more infromed RIs’ decisions. Qualitative interviews were conducted with experienced RIs (n = 8). Secondary data were gathered from YouTube recordings (n = 44). Thematic analysis and Retrieval-Augmented Generation (RAG) methodology was used for data extraction and analysis of the scripts. The findings indicate that while LLMs have the potential to enhance accessibility to expert opinions and provide more informed investment decisions, they are unlikely to replace human experts. RIs show a preference for combining LLM insights with human expertise, recognising the limitations of LLMs in managing complex and nuanced investment information. The study highlights the usefulness of the TPB as a framework for the exploration of the topic. It also introduces a novel research method - advanced data extraction techniques on a vast unstructured dataset.?Results contribute to the understanding of LLMs potential in supporting RIs and confirms the usefulness on the AESTIMA tool for data extraction and analysis.
Bois pourri et santé des forêts : exemple du mélange épicéa (Picea abies [L.] Karst.) et mélèze (Larix decidua Mill.) en forêt subalpine de Sainte-Foy-Tarentaise (Savoie)
Authors: Bernier Nicolas , Trosset Jean-Yves
Published: February 2025

La coexistence du mélèze et de l’épicéa est interrogée à la lumière des multiples pressions que subissent les forêts subalpines. L’hypothèse énoncée par cette étude est que l’impact de la durée d’ensoleillement, de la végétationconcurrente et de la forme d’humus (les trois composantes majeures de la niche de régénération) s’exerce à l’échelle du mètre. Cette étude démontre le rôle important du bois pourri dans la régénération forestière, contrariant ainsi la vision d’une forêt s’écroulant sous l’accumulation de sa nécromasse (phase de « sénescence »). Notre rapport aux forêts doit donc se nourrir d’un dilemme qui interroge l’impact réel de l’exportation de bois sur la santé de cet écosystème.
Messages clés :- Sénescence et régénération sont interdépendants. Ils sont le reflet de la santé de la forêt.- Le bois mort au sol n’est que « la partie émergée de l’iceberg ». L’essentiel est incorporé à l’humus.- Il faut ajouter la santé aux quatre fonctions forestières déjà reconnues, qui sont : la production, la protection, la récréation, la conservation.
Apport de la télédétection pour la cartographie du dépérissement forestier des chênes en région Centre-Val de Loire
Authors: Mouret Florian , Beaudonnat Louise , Morin David , Planells Milena , Martin Hilaire , Vincent-Barbaroux Cécile
Published: February 2025

Ce travail a pour ambition de caractériser l’ampleur du phénomène de dépérissement des chênes dans la région Centre-Val de Loire à l’aide d’images satellites Sentinel-2 et d’un modèle de classification supervisée. Cette étude propose d’analyser en détail comment le modèle de classification utilise les séries temporelles d’indices Sentinel-2 pour détecter le dépérissement. Il apparaît que de faibles teneurs en eau (corrélées à l’infrarouge moyen) pendant l’été sont déterminantes pour détecter le dépérissement. Les cartes produites ont également été croisées avec d’autres données environnementales qui montrent que les dépérissements des chênes sont fortement associés à l’intensification de l’évapotranspiration de ces dernières années.
Messages clés :- Il est possible de détecter avec précision les dépérissements forestiers du chêne à l’aide d’images satellites Sentinel-2.- Une cartographie de l’état sanitaire des chênaies a été produite sur plusieurs années pour l’ensemble de la région Centre-Val de Loire et ses environs.- Notre analyse met en avant l’importance du contenu en eau de la canopée en été comme facteur le plus déterminent pour détecter les dépérissements.
Le bois du Baradat, deux siècles et deux révolutions d’une superbe chênaie de l’Adour
Authors: Bartoli Michel , Doly Gilberte
Published: February 2025

Les riches archives de la commune de Vic-en-Bigorre ont permis de suivre la totalité des actions sylvicoles dans la petite futaie du Baradat, chênaie pédonculée « de l’Adour » à croissance très rapide et de haute qualité. Du milieu du XVIIe siècle à celui du XIXe, se succèdent des coupes suivant les pratiques de l’Ancien Régime puis, à partir de 1797, des coupes avec éclaircies. Mais l’Administration des forêts, qui voyait dans le Baradat « sans contredit un des plus beaux [bois] qu’il y ait en France » (1824), en accepta le défrichement (1857) et le remplacement par un semis de glands sur 30 hectares, voisins dont les produits furent récoltés en 1980…
Messages clés :- Une croissance rapide des Chênes ne déprécie par leur qualité.- En deux révolutions complètes, un historique complet des coupes dans une très petite futaie régulière permet de suivre correctement l’évolution des pratiques et des idées sylvicoles du XVIIe au XIXe siècle.
Design and Evaluation of Compliant Hinges For Deployable Thick Origami Structures
Authors: Lee Munkyun , Tachi Tomohiro
Published: February 2025

Origami models are often idealized by discrete folding of zero-thickness sheets; however, the sheet thickness and the elastic limit of the material cannot be ignored in engineering practice. One solution for realizing thickness is the compliant hinge, which realizes the folding deformation
in the elastic range of the material by replacing the crease line with a wide deformation zone where the compliant structure is installed. However, the compliant hinge has several limitations. First, it cannot maintain the center of rotation (CoR) between panels during the folding motion.
This makes origami structures with interior vertices not transformable because the crease lines are no longer concurrent. Second, the play caused by the wide deformation zone increases the degree of freedom of the origami structure, leading to instability. To solve these problems, we propose
three types of new compliant hinges. We provide two evaluation methods: the play is evaluated using eigenvalue analysis, and the change CoR under unideal load conditions is evaluated using FEM analysis.
Topic: Leveraging Agile and Hybrid Models to Advance Sustainability Initiatives in the Oil and Gas Industry
Authors: Larbi Samuel Yaw , Boakye Kwaku , Fakeyede Mobolaji , Asimolowo Adewale Joshua , Owusu Frederick , Omole Ogooluwa Korede , Omuvwie Enita Anita
Published: February 2025

Environmental concerns, strict guidelines, and social needs are piling pressure on the oil and gas industry to change their practice to be more sustainable. This review looks at how Agile and Hybrid project management methodologies can help address these efforts while balancing flexibility and structure, and managing issues such as regulatory compliance and stakeholder engagement. The review through case studies demonstrates the increases in adaptability, collaboration, and innovation that Agile’s iterative processes provide. It is especially useful to address dynamic issues, like green energy schemes, or cutting carbon footprints. Agile models on the other hand, alternatively fuse the flexibility of Agile with the structure of Waterfall, manage to bring the requirement of stability for such compliance-intensive projects. Taken together these methodologies provide a balanced matrix for managing sustainability efforts in complex contexts. Nevertheless, these methods are not easy to implement. However, these are usually impeded by cultural resistance, high costs and regulatory complexities. Leadership, employee training and the use of new technology such as AI and digital twins are all critical ways to get around these hurdles and achieve better outcomes, the review concludes. Finally, Agile and Hybrid models are valuable tools for the progress of sustainability in the oil and gas industry, following many macro goals (such as the United Nations Sustainable Development Goals (SDGs). This review offers practical guidance for field leaders and policymakers to hasten sustainable progress in this important area.
Limitation of Ammonia Exposure among Workers in Fertilizers Industry Using Modern Modified Technology Towards Sustainability
Authors: Elhadad Safinaz M. , Mansour Taher A. , Elshibiny Ibrahim A. , Elmarakby Fadia A.
Published: February 2025

Background: Fertilizer production is a worldwide industry. Workers in the production process area may be exposed to mineral dust, water-soluble and insoluble compounds, nitric acid, nitrogen dioxide, nitrogen monoxide, ammonia (NH3), and hydrogen fluoride which might be emitted into the work environment in the different departments.
Subjects and methods: The study was conducted in one of the modern nitrogenous fertilizer companies in Alexandria, Egypt. The company specializes in producing high quality nitrogenous fertilizers, mainly Granular Urea (46%) as a final product and Anhydrous NH3 as an intermediate product using advanced technology. The study involved descriptive research adopts a quantitative and case study approach. Pre-designed and pre- tested structured two questionnaires for workers' data were used. The first questionnaire (A) was used for professional characters and occupational hygiene profile. The second questionnaire (B) was an optimal symptom score for employees’ complaints and their awareness about the occupational exposure to NH3. NH3 gas was measured in the ten different working areas in the factory. A direct reading- infrared spectrophotometry method was used.
Results: The NH3 synthesis factory is based on reliable and proven process steps controlled through automated operation of plants and machines. In the urea plant, the possible and available emission reduction techniques were used. All workers are males (100%). Current position includes specifications as technicians (n=125, 74.4 %) and engineers (n=43, 25.6%). The technicians' job duties are operation (n=77, 61.6%), production (n=2, 1.6%), maintenance (n=32, 25.6%) and inspection (n=14, 11.2%). Otherwise, the engineers ' job duties are operation (n=33, 76.7%), production (n=1, 2.3%), and maintenance (n=9, 20.9%). Work regime is day shift (n=119, 70.8%), and night shift (n=49, 29.2%). The total number of working hours/week ranges from 24-48 hours with a mean of 47.68±1.85 and a median of 48 hours. Considering the availability and usage of personal protective equipment (PPE) (n=167, 99.4%) and no smoking habits (n=168,100%), this reflects the increased knowledge and awareness, and the promoted safety culture of both the management and the employees. There is a statistically significant difference between the years of employment and the median for eyes, nose and sinuses symptoms (P = 0.001, 0.019 and 0.009 respectively). Regarding the mean concentration of NH3 in the different working stations, it was found to be lower than the Threshold Limit Value- Time weighted average (TLV-TWA) of NH3 which is 25 ppm.
Conclusion: The current study highlighted the role of applying modern modified industry in limiting exposure to potential occupational hazards, improving the health of the workers, and achieving sustainability.
Neither uni- nor multi-modal exercise interventions improve single- and dual-task gait performance in physically active healthy elderly – a pilot study
Authors: Freitag Constantin Wilhelm , Behrens Martin , Bielitzki Robert , Behrendt Tom , Al-Nosairy Khaldoon O. , Stolle Francie H. , Prabhakaran Gokulraj T. , Beyer Rosalie , Thieme Hagen , Hoffmann Michael , Schega Lutz
Published: February 2025

Purpose: Aging is an inevitable process leading, inter alia, to the loss of muscle mass as well as the decrease in physical and cognitive function. These age-related impairments translate into a reduced gait performance and an increased risk of falls, which can be tackled with resistance training, Unimodal intervention (UMI). However, Multimodal intervention (MMI), i.e. combined motor-cognitive and resistance training, might be a more promising approach to increase physical and cognitive function in old adults. Therefore, this pilot study aimed to investigate the effects of MMI, compared to UMI, on gait and cognitive performance in elderly participants. We hypothesized that MMI will increase gait and cognitive performance to a larger extent than UMI.
Methods: In this two-arm randomized controlled pilot study, 29 healthy active elderly participantswere assigned to MMI (15 participants, 72.0±5.5 years) and UMI (14 participants, 70.1±4.7 years). Both groups trained for 12 weeks, two times a week for 60 min, respectively. MMI consisted of motor-cognitive training directly followed by resistance training, while UMI consisted of a stand-alone resistance training. Three weeks before and after the interventions, gait performance (e.g., stride length, velocity, minimum toe clearance) was assessed during single- and dual-task walking trials using inertial measurement units. During dual-task walking, participants walked and concurrently performed different cognitive tasks in a random order: (i) reaction time task, (ii) N-back-task, and (iii) letter fluency task with two difficulty levels, respectively. Data were analyzed with repeated measures analyses of covariance (Time×Intervention×Condition).
Results: Although the analyses of the progression of the external load used during resistance training showed a significant increase over the training period (e.g. leg press p<0.001, η2p=0.618), there was no improvement of gait or cognitive performance in active old adults after neither MMI nor UMI.
Conclusion: Against our hypothesis, the present pilot study indicated that neither a 12-week MMI nor UMI seems to have a sizable impact on gait parameters and cognitive performance in physically active healthy adults. Still, a significant increase in the external load used during resistance training was observed, implying neuromuscular adaptations, which, however, did not translate into a higher gait and/or cognitive performance.
Investigating the mental health burden amongst breast and cervical cancer patients in Rwanda using a modified self-reported questionnaire for mental health screening (SRQ- 20): A validation study
Authors: Rusatira Jean Christophe , Uwimana Jean Berchmans , Rutagumba Dieudonne , Byiringiro Samuel , Natta Saswathi , Espmark Johannes , Rurangwa Eric , Kågesten Anna E. , Nzeyimana Innocent , Ndoli Andrea Diane
Published: February 2025

Background
Despite continued advancement in cancer care, mental health support has been inadequately integrated, particularly for female breast and cervical cancer in low- and middle-income countries. This study aims to address this gap by validating a mental health screening tool and apply it to investigate the mental health burden and associated factors among this patient population in Rwanda.
Methods
A cross-sectional study was conducted with 437 breast and cervical cancer patients who sought care at six major cancer care hospitals in Rwanda between October 2022 and February 2023. The survey questionnaire included questions about participant’s socio-demographic characteristics, cancer diagnosis and care, mental health, sexual and gender-based violence (SGBV) experience, and sexual health. Descriptive statistics were used to summarize patients’ characteristics. Psychometric analysis was conducted to validate the modified self-reported questionnaire (SRQ-20) for mental health screening, generating unweighted mental health scores for each woman on a X-20 scale. Prevalence estimates of mental health follow-up needs were calculated, and multivariable regression analysis were conducted to identify factors associated with mental health follow-up needs.
Results
The items used for mental health screening loaded on two distinct factors named “Anhedonic symptoms” and “Psychomotor changes” (Chronbach’s alpha = 0.92). The overall average mental health score was 9.6. The overall prevalence of mental health follow-up need was 38.9%. In adjusted regression models, mental health follow-up was associated with lifetime experience of physical or sexual violence (aOR = 2.59, 95% CI 1.25, 5.39), having experienced sexual dysfunction after cancer treatment initiation (aOR = 2.11, 95% CI 1.15, 3.88), being in the age category of 50–65 (aOR = 0.36, 95% CI 0.14, 0.91), and having a partner who is perceived as not satisfied with sexual life before and after cancer diagnosis (aOR = 2.49, 95% CI 1.20, 5.17).
Conclusions
The modified SRQ-20 questionnaire is a valid tool for mental health screening among breast and cervical patients in Rwanda. The need for mental health follow-up in this population is high and cancer care needs to integrate psychotherapy for the couples, alongside interventions targeting sexual and gender-based violence and sexual health care.
Knowledge of Consequences and Sociodemographic Variables as Predictors of Drug Abuse Among Secondary School Students in Semi Urban, Nigeria
Authors: Olabisi Oluwaseyi Isaiah , Owoeye Michael Olumide , Samuel-Ajayi Yetunde Abiola , Olabisi Tolulope Esther , Oladepo Eniolaoluwa Peace , Odira Chika
Published: February 2025

Introduction
Drug abuse is a major public health concern globally. This study assessed the level of drug abuse and knowledge of secondary school students on the consequences of drug abuse. It also determined whether the knowledge about the consequences and sociodemographic variables predicts the level of drug abuse.
Methods: A descriptive cross-sectional design was utilized. This study was conducted among 440 senior secondary school students in four selected secondary schools in a semi-urban area in Oyo State, Nigeria. The Drug Abuse Screening Test (DAST 10) and Knowledge of the Consequences of Drug Abuse (KCDA) were used to collect the data. Frequency and percentages were used to summarize the sociodemographic variables, the knowledge of the consequences of drug abuse, and the level of drug abuse. Multivariate regression analysis at p<0.05 was done to ascertain the prediction of drug abuse.
Results
Out of 440 students that participated in the study, 283 (64.3%) were females, and 308 (70.0%) were between 13 and 15 years of age. More than half of the students were at the moderate level of 298 (67.7%) of drug abuse. whoAge (β = 0.171; p = 0.036) and class (β = 0.684; p = 0.025) predict drug abuse. Knowledge about the consequences of drug abuse as impaired judgment and decision making (β = 0.504. p = 0.031), mental illness (β = 2.145; p = 0.012), and death (β = 1.165; p = 0.023) also predict the drug abuse among the students.
Conclusion
The students abused the drug at a moderate level. Age, class of the students, and knowledge about the consequences of drug abuse, including impaired judgment and decision-making, mental illness, and death are predictors of drug abuse. Therefore, there is need to create more awareness on the consequences of drug abuse among secondary school students. Moreover, age-specific programmes and class-level interventions should be designed and implemented to address adolescent drug abuse.
Evaluating recruitment, retention and adherence patterns in the GET FIT fall prevention exercise trial in older, postmenopausal cancer survivors
Authors: Sitemba Jessica , Crisafio Mary , Li Fuzhong , Eckstrom Elizabeth , Winters-Stone Kerri M.
Published: February 2025

Purpose
The GET FIT trial tested fall prevention exercise approaches in older (50–75 years) post-chemotherapy, postmenopausal cancer survivors. We describe recruitment, retention, and adherence patterns from GET FIT to inform future trials.
Methods
Participants were recruited through multiple strategies (e.g., cancer and research registries, clinician referral, outreach, electronic health record (EHR) screening) and were randomized to one of three supervised, facility-based, group exercise programs for six months. We compared effectiveness of accrual across recruitment strategies, examined characteristics of women who completed the interventions to those who withdrew, and women with good (≥ 50%) versus poor (< 50%) adherence to training.
Results
Of 1490 interested women, 442 women were eligible, randomized, and received the assigned intervention (30% accrual rate). Accrual was similar across recruitment strategies, except for EHR screening which yielded no accruals. Retention over 12 months was 87% with most dropouts occurring within the first month. There were no differences in baseline characteristics between women who did or did not drop out. Poor adherers (n = 60) had higher baseline BMI, comorbidities, pain, disability and lower physical functioning (p < 0.05) compared to more adherent women (n = 377).
Conclusions
A variety of recruitment strategies appear to be effective for enrolling older, postmenopausal cancer survivors into a facility-based exercise trial, except for directly approaching women identified through the EHR. Women with poorer health were at risk for study drop-out and poor adherence to exercise.
Implications for Cancer Survivors:
Women with poorer initial health may need additional retention strategies to help them stick with supervised, facility-based, group exercise.
A META-ANALYSIS FOR ANALYZING CHANGES IN SERUM-FREE T4 LEVELS WITH METFORMIN TREATMENT INPATIENTS WITH OR WITHOUT THYROID DISEASE AND/OR DIABETES
Authors:   Internal Medicine Icahn School of Medicine at Mount Sinai, Queens, NY, US, Maheshwari Mashal , Kumar Maheshwari Karan ,   Internal Medicine Icahn School of Medicine at Mount Sinai, Queens, NY, US, Shehryar Muhammad ,   Internal Medicine Icahn School of Medicine at Mount Sinai, Queens, NY, US, Advani Poonam ,   Internal Medicine Icahn School of Medicine at Mount Sinai, Queens, NY, US, Sachmechi Issac ,   Internal Medicine Icahn School of Medicine at Mount Sinai, Queens, NY, US
Published: February 2025

Context: Previous studies suggestthe effect of metformin on TSH levels, but its impacton free T4 (fT4) levels has not been understood clearly.

Objective:This Meta-analysis aims to studythe effects of metformin on serum-free T4(fT4) levels in patients with or without underlying thyroid disease and/or diabetes.

Data Sources:We reviewed articles from the Cochrane Library based on the systematic protocol.

Data Extraction: Demographic, clinical, and relevant data was extracted. Data were analyzed according to the changes in fT4 levels with metformin administration.

Data Synthesis: A total of 5 datasets (475 patients) were included in our analysis. There was a reduction in free thyroxine levels evident bythe statistically significant mean difference in this meta-analysisin the treatment group between the baseline levels and post-follow-up (Metformin MD= 1.0 pg/ml, CI=0.3423 to 1.657, P value=0.005).

Conclusion:While this meta-analysis found no significant overall effect of metformin on fT4 levels in patients with or without underlying diabetes or thyroid disease, the results from individual studies like Oleandri et al. (1999) suggest that metformin may cause a slight decrease in fT4 levels. However, given the small effect size and minimal clinical significance, the impact of metformin on fT4 levels remains uncertain and warrants further investigation to better understand its clinical relevance. Clinically, anthropometric and metabolic characteristics can alter these levels differently in each case. Dose adjustment for Levothyroxine (LT4) replacement in patients is the main concern when metformin is given concomitantly.
Effect of carbohydrate-protein supplement on anaerobic capacity after physical activity
Authors:   Faculty of Sport and Health Sciences, Thailand National Sports University, Chaiyaphum Campus, Chaiyaphum, Thailand, Limnararat Kornthip
Published: February 2025

The study examined how carbohydrate-protein (CHO-PROT) beverages affect anaerobic capacity after exercise. Fifteen male university football players, aged 20–25, participated in a 90-minute cycling session while consuming one of three drinks: CHO-PROT, carbohydrate-only (CHO), or a placebo (PLA). Results analyzed with two-way repeated measures ANOVA and pairwise comparisons (Bonferroni’s method, p<.05) showed that the CHO-PROT group experienced less decline in peak power during and after exercise compared to the PLA group (p<.01). Both CHO-PROT and CHO groups showed smaller reductions in mean power at the 90th minute of exercise compared to the PLA group (p<.01), and the CHO-PROT group maintained better mean power 24 hours after exercise (p<.05). Blood glucose levels increased more in the CHO-PROT and CHO groups than in the PLA group at all times (p<.01). The CHO group also showed a smaller drop in blood glucose at the 90th minute of exercise compared to the PLA group (p<.01). No significant differences were found in blood lactate levels between groups. Muscle soreness was lowest in the CHO-PROT group and lower in the CHO group compared to the PLA group at all times (p<.01). In summary, CHO-PROT drinks improved anaerobic performance, raised blood glucose levels, and reduced muscle soreness, with no effect on blood lactate levels.
How do you evaluate me? A systematic review of conversational agents supporting self-management in persons with a chronic disease (Preprint)
Authors: Peerbolte Tessa F , van Diggelen Rozanne A , van den Haak Pieter , Geurts Kim , Evers Luc W.J. , Bloem Bastiaan R , de Vries Nienke M , van den Berg Sanne W
Published: February 2025

BACKGROUND

Chronic diseases necessitate effective self-management strategies to improve health outcomes and reduce healthcare demand. Conversational agents (CAs) offer promising, scalable, personalized solutions, yet robust evidence of their efficacy remains limited.

OBJECTIVE

This systematic review examines CA characteristics, integration of behaviour change techniques, and evaluation methods to guide future research and intervention design.

METHODS

We conducted a systematic search in PubMed to identify studies that evaluated the efficacy of CAs for chronic diseases self-management published from 2018 onward. Data extraction was guided by conceptual frameworks to ensure comprehensive reporting of intervention and methodologies: the Behavioral Intervention Technology model; and the CONSORT eHealth checklist.

RESULTS

Twenty-four studies were included, primarily focusing on text-based, rule-based CAs delivered via mobile applications. The chronic diseases predominantly targeted were diabetes and cancer. Commonly identified clusters of behaviour change techniques were ‘Shaping knowledge,’ ‘Feedback and monitoring,’ ‘Natural consequences,’ and ‘Associations’. However, reporting of behaviour change techniques and their delivery was lacking, and intervention description was limited. Studies were mostly early phase, with a great variety in intervention description, study methods and outcome measures.

CONCLUSIONS

Advancing the field of CA-based interventions requires transparent intervention description, rigorous methodologies, consistent use of validated scales, standardized taxonomy and reporting aligned with standardized frameworks. Enhanced integration of AI-driven personalization and a focus on implementation within healthcare settings are critical for future research.

CLINICALTRIAL

Our protocol was not registered.
Novel internet advertising approach to raise public awareness about metabolic dysfunction-associated steatotic liver disease (Preprint)
Authors: Inoue Kaori , Araki Kaoru , Shibayama Kaoru , Yada Tomomi , Hara Nagisa , Oeda Satoshi , Udo Kazuma , Tobu Shohei , Yamashita Shun , Isoda Hiroshi , Eguchi Yuichiro , Anzai Keizo , Noguchi Mitsuru , Takahashi Hirokazu
Published: February 2025

UNSTRUCTURED

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD), which causes cirrhosis and liver cancer, is globally prevalent. Analyses of Internet searches for the term “fatty liver” are needed, as well as effective methods to raise awareness about MASLD.
Methods: In this retrospective analysis, we determined cooccurrence terms for “fatty liver” and conducted a search term history. Key terms associated with searches for “fatty liver” were identified. In a case control study, a banner advertisement regarding MASLD was provided to individuals searching for our key terms (key term group: KTG) or provided randomly (control group: CTR). The banner advertisement redirected viewers to an educational cartoon, followed by a questionnaire survey.
Results: The cooccurrence term “how to treat” was the most frequently searched with “fatty liver.” The search term history revealed that people searched for various terms. Search terms associated with lifestyle-related diseases and diet were most frequent. “Diet,” “blood sugar level,” “cholesterol,” “triglyceride,” “visceral fat,” and “antihypertensive drugs” were defined as key terms. In the case control study, the number of banner advertisement views by the KTG and CTR groups was 5,864,184 and 49,388,176, respectively. The KTG group had a significantly higher click-through rate for the advertisement than the CTR group (0.097% vs. 0.063%; p<0.001). The KTG group more frequently responded to the questionnaire survey than the CTR group (3.22% vs. 0.84%, p<0.001) and had greater intention to receive medical care as early as possible (74 people, 60.2% vs. 73 people, 42.4%; p=0.003).
Conclusions: An advertising approach based on search term analyses can increase awareness about MASLD among the general public and might contribute to individuals with MASLD receiving appropriate medical care.
Risk Mitigation of Fresh Milk Supply Chain Based on Vulnerability Analysis in Boyolali Regency, Indonesia
Authors: Annisa Warastra Nur , Guritno Adi Djoko , Sukartiko Anggoro Cahyo
Published: February 2025

Fresh milk in Boyolali Regency is currently unable to meet the demand of the processing industry because the quantity is limited and the quality is below the standard. The large number of activities at each tier and the long supply chain flow for fresh milk have the potential to cause a decrease in quality and quantity, making it vulnerable to risk. Therefore, this research aimed to analyze risk management in supply chain and provide mitigation proposals. Data were collected by in-depth interviews with 51 respondents using purposive and snowball sampling techniques. The variables examined include supply chain flow of fresh milk, risks at each tier, causes and impacts of risks, as well as likelihood, severity, and capacity to manage risk. Data processing used ISO 31000:2018 and the Rapid Agricultural Supply Chain Risk Assessment (RapAgRisk) method to assess risk vulnerability. The results showed that in Boyolali Regency, fresh milk supply chain consists of four tiers, namely farmers, as well as milk couriers, collectors, and processors, comprising processing industry and street vendors. Mitigation proposals were given for nine risks in the categories of high, moderate, and low vulnerability. These risks include high animal feed prices, low forage availability, cows being attacked by foot and mouth disease (FMD), adulteration of fresh milk, the amount of fresh milk received by couriers and collectors fluctuating, rejection, sudden demand, and excess stock of fresh milk. Subsequently, risk mitigation proposals were provided to maintain quality and increase fresh milk production.
Physicochemical Characteristics of Potato (Solanum tuberosum L.) after Chitosan Coating and Storage at Various Temperature
Authors: Mudyantini Widya , Pramesthi Vionita Dyah , Suranto Suranto , Solichatun Solichatun , Pitoyo Ari , Suratman Suratman , Purnama Purin Candra
Published: February 2025

Potato (Solanum tuberosum L.) plant is widely favored due to its versatility in various processed products, but perishable. This study aimed to determine the effect of chitosan coating and storage at various temperatures on the physiological and chemical characteristics of potato tubers. This research used 2 variables, namely the concentration of chitosan (0, 1, 1.5 and 2%) and storage temperatures of 0, 10 and 25°C. The parameters observed included tuber skin color, weight loss, hardness, the thickness of the chitosan layer and tissue penetration, oxygen levels, water content, starch degradation, reduced sugar content, and sprouting amount. Furthermore, data were analyzed using the Analysis of Variance (ANOVA) test. The results showed the effect of chitosan coating and storage temperature on weight loss, color, oxygen level, hardness, water content, starch degradation, and reduced sugar content in potato tubers during storage. The most effective treatment was 1.5% chitosan coating combined with a storage temperature of 10°C.
Root System Traits and Their Association with The Yield of Safflower under Different Irrigation Regimes
Authors: Ganji Masomeh , Galeshi Serolah , Jabbari Hamid , Sanjarian Forough , Torabi Benjamin
Published: February 2025

Root system is recognized to play a crucial role in enhancing plant tolerance and stability during drought conditions. Therefore, this study aimed to assess safflower (Carthamus tinctorius L.) genotypes under various irrigation regimes and explore the relationship between root traits and yield. A two-year factorial experiment was conducted with three spring safflower genotypes, namely Parnian, Goldasht, and Kazak under two irrigation regimes, including full and deficit. Irrigation treatments maintained residual moisture levels at 60% and 20% of available water. Root traits such as biomass (RB), length (RL), diameter (RD), dry weight (RDW), and root length density (RLD) were measured. Additionally, seed yield (SY), yield components, and oil content (OC) were assessed in all treatments. The results showed that drought stress reduced safflower RB and RL, but Kazak genotype had a significant increase in RDW (48%) and RL (12%) under deficit irrigation. Root biomass distribution and RLD varied among genotypes across soil layers. Parnian and Goldasht genotypes had the highest root biomass at 30 cm depth with full irrigation, while Kazak showed the highest values at 60-90 cm depth under deficit irrigation. Drought stress significantly reduced safflower SY by 71% and Kazak genotype showed the highest SY under deficit irrigation, suggesting better performance stability. SY had a strong positive correlation with RDW (0.57) and RD (0.84), indicating a significant relationship. Furthermore, SY was significantly correlated with RLD at depths of 60-90cm (0.72-0.68). These results suggested that root traits such as RDW, RD, and RLD in deeper soil layers were crucial for breeding programs aiming to develop drought-tolerant genotypes.
A Critical Analysis of Lexicon and Phonological Development through Children’s Songs in First Language Acquisition
Authors: Ma Zhi
Published: February 2025

This paper investigates the significance of children’s songs in promoting vocabulary and phonological development during first language acquisition, especially within diverse and multicultural educational contexts. It adopts Sociocultural, Postmodern, and Interactionist theoretical frameworks to analyse the influence of these songs on language learning. Sociocultural theory emphasises the crucial role of social interactions and cultural relevance in language development. In contrast, Postmodern theory critiques the cultural biases frequently found in traditional song selections and advocates for broader inclusive linguistic representation. Interactionist theory underscores the importance of interactive and multisensory experiences in facilitating language acquisition. The study finds that children’s songs’ repetitive structures and rhythms significantly aid vocabulary development and phonological awareness. However, it also identifies challenges such as cultural biases and limited opportunities for individual feedback in group learning environments. To address these issues, the research recommends expanding the repertoire of songs to include diverse linguistic and cultural elements, promoting equity in language learning and fostering a richer cultural understanding. The paper underscores their potential as practical tools for promoting language development while catering to learners’ varied needs by situating children’s songs within a broader, inclusive teaching framework.
EVALUATION OF THE DETERMINATION AND IMPLEMENTATION OF BEYOND-USE DATE (BUD) TO NON-STERILE EXTEMPORANEOUS COMPOUNDED MEDICINES BY PHARMACISTS IN SUKOHARJO INDONESIA
Authors: KARUNIAWATI HIDAYAH , HI MARSILIA ROSA SINENSIS
Published: February 2025

Objective: This research aims to evaluate pharmacists' determination and implementation of Beyond-Use Date (BUD) for extemporaneously compounded medicines from non-sterile drugs and the factors that influence it.
Methods: This research is a non-experimental cross-sectional study that used a validated questionnaire with the cluster sampling method applied to select pharmacists. The data were analyzed statistically using the Mann-Whitney, Kruskal Wallis tests and Spearman Correlation.
Results: Of the 181 pharmacists who participated, 161 (89.0%) were aged 26–45 years, 160 (88.4%) were women, 118 (65.2%) were married, and 173 (95.6%) had a bachelor's degree with a profession. Around 75%–77% of respondents calculate BUD on the extemporaneous compounded and mark BUD on the drug label or medicine packaging. Around 80% of pharmacists inform patients about BUD, but only 65% ensure patients understand it. Age, marital status, education level, length of work experience, and income significantly influence the determination and implementation of BUD (P<0.05). Knowledge has a significant relationship with pharmacists' attitudes (r = 0.836) and behavior (r = 0.646) towards BUD
Conclusion: The role of pharmacists in determining and implementing BUD in extemporaneously compounded medicines needs to be improved to ensure maximum drug quality, safety, and optimal therapy.
FORMULATION AND STABILITY EVALUATION OF GELS CONTAINING CHITOSAN MICROPARTICLE-LOADED BEETROOT (BETA VULGARIS, LINN) FOR TOPICAL SKIN BRIGHTENING
Authors: SUKMAWATI ANITA , WAHYUNINGRUM SHINTA JANNATI , UTAMI MAGHFIRATUL LAILIYAH
Published: February 2025

Objective: The objective of this research is to investigate the effect of Hydroxypropyl Methylcellulose (HPMC) concentration as a gel base for chitosan microparticle-containing beetroot (Beta vulgaris, Linn) toward gels stability and skin brightening effect.
Methods: Ionic gelation was used to make microparticle using chitosan 1% solution and beetroot dry extract as active component. Scanning Electron Microscope (SEM) and active substance loading were used for physical characterisation. The MP then was added to HPMC-based gels at 0.5, 1.0, and 1.5% w/w. Gels were tested for viscosity, pH, and active component stability. Gels were tested for skin lightening on humans.
Results: Results reveal beetroot extract may be loaded into chitosan microparticle with a Drug Loading (DL) of 23.27±0.057% w/w. HPMC gels had a pH of 5-5.4 and increased viscosity related with HPMC content. Gels showed colour instability after 6 cooling-heating cycles and decreased betanin levels on day 7 at 40±2 °C and RH 75±5%. HPMC 0.5% gel brightened human skin more than other HPMC gels.
Conclusion: The 0.5% HPMC gel base had the smallest betanin reduction during the accelerated stability test, compared to the 1.0 and 1.5% HPMC gels. The formulation of chitosan microparticle gel loading beetroot extract with 0.5% HPMC gel base had brightened skin better than the other two formulae.
SYNTHESIS OF BLACK TURMERIC EXTRACT NANOPARTICLES (CURCUMA CAESIA) AND ITS CYTOTOXIC ACTIVITY ON T47D CELLS
Authors: DA’I MUHAMMAD , AZIZAH NUR , RAHMANA ANDREA Y , NURWAINI SETYO , WIKANTYASNING ERINDYAH R
Published: February 2025

Objective: This study aimed to formulate black turmeric into nanoparticle preparations with various concentrations of chitosan and determine its cytotoxic effect on T47D breast cancer cells.
Methods: Extraction was carried out by the maceration method. Black turmeric condensed extract was formulated into nanoparticles using the ionic gelation method, which was a method that relies on the cross-linking agent sodium tripolyphosphate (Na-TPP). The cytotoxic activity of black turmeric extract was tested using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay method.
Results: The results showed that black turmeric extract nanoparticles have a size range of 266-558 nm and were positively charged with zeta potential values ​​ranging from 3.3 to 9.7 mV. The encapsulation efficiency of black turmeric extract nanoparticles was 63.42%. The results of the cytotoxic test showed that both black turmeric extract and black turmeric extract nanoparticles showed moderate cytotoxic activity, with the IC50 values ​​of the two preparations were 78.60 µg/ml and 162.95 µg/ml, respectively.
Conclusion: The results obtained in this research indicate a promising potential of nanoparticles of black turmeric extract as a cytotoxic agent for the treatment of breast cancer.
EXPLORATION OF ETHNOVETERINARY MEDICINE FOR CATTLE’S LUMPY SKIN DISEASE IN INDONESIA: NARRATIVE REVIEW
Authors: CHOLISOH ZAKKY , NURINNAFI’A AHDA M. U. , SURANTO  , WIKANTYASNING ERINDYAH R.
Published: February 2025

Objective: Lumpy Skin Disease (LSD) is a condition characterized by the development of nodules on the skin of affected cattle. Typically, it impacts bovine animals such as cattle and buffalo. Ethnoveterinary medicine focuses on the application of traditional medicine to animals. The efficacy of traditional medicine in addressing the symptoms of lumpy skin condition was established through empirical research. Farmers can utilize medicinal plants from traditional medicine to treat bovine LSD. The primary objective of LSD treatment in cattle is to address the clinical symptoms. The objective of this study was to examine the use of LSD treatment in indigenous medicine in Indonesia.
Methods: A review was conducted primarily targeting traditional medicines that have gained interest as potential treatments for cattle infected with Lumpy Skin Disease Virus (LSDV). Government authorities have specifically advised some precautions, while national mass media has raised awareness about further measures.
Results: The screening result indicates that there are 9 plant species which can be used in the traditional treatment of cattle to cure LSD e. g. Nicotiana tabacum, Acorus calamus, Allium sativum, Annona muricata, Piper betle, Zingiber officinale, Curcuma xanthorrhiza, Kaempferia galanga, and Curcuma domestica, which have antimicrobial, anti-inflammatory, antioxidant, analgesic, immunostimulant, antidepressant, wound healing, and insect/larvae repellant. This research aims to contribute to the advancement of LSD treatment using conventional herbal remedies.
Conclusion: Evidence from the study revealed the significance of said plants against LSDV, especially in Indonesia.
El problema del “indio” en la universidad nacional San Marcos de Lima (1879-1909)
Authors: Heredia-Neyra Juan José
Published: February 2025

El presente estudio toma distancia de las clásicas aproximaciones que consideran a la Universidad de San Marcos como cantera del racismo científico y legitimadora del orden oligárquico. Siguiendo a Clemente Palma, se creyó que en la universidad se buscaba la exterminación del indígena y que reinaba una mentalidad racista y excluyente. En el presente estudio se demuestra que un sector importante de la universidad refutaba el racismo científico y proponía incluir al “indio” en la nación peruana. Con este fin, los autores se sirven de la gran historia prehispánica para probar que, pese a su degeneración, el indígena podría recuperar su grandeza. Igualmente, usan las ideas de pensadores europeos críticos del racismo científico. Finalmente, se sirven del despegue japonés y su triunfo en la guerra contra Rusia de 1904-1905 para demostrar que las “razas” que habían degenerado podrían regenerarse. Sin embargo, los dispositivos de redención que proponían significaban su desindianización.
Health Monitoring Using IOT
Authors: Khan Shoaib Nadeem
Published: February 2025

A pulse oximeter is used to measure a persons oxygen level; this indicates the ratio of oxygen-carrying molecules in the
blood that carry oxygen. It is important to assess saturation oxygen levels in cases where patients are at risk of overdose, as the
global spread of COVID-19 has now reached a pandemic-free state. Currently, with no cure and limited vaccines, the novel
coronavirus has had a significant impact on public health, society, and the global economy that will last for years. IoT platforms
are the first choice to achieve this due to their intuitive capabilities and seamless connectivity. IoT technology is changing our
lives through smart healthcare, smart cities, or smart buildings to create a simpler and smarter society. We will measure the
saturation point oxygen content in our body with the pulse and this information will be stored in the system and made available
to users. Use a pulse oximeter to monitor a person's oxygen level and heart rate. Pulse oximeters are designed to use infrared
and visible light to transmit light from a transmitter through a person's finger. Suction indicates that blood is flowing through
your finger and displays oxygen and pulse results. The output of this analog circuit is connected to the NodeMCU, which
calculates the heart rate and oxygen level based on these values. Results will be displayed and viewed on the app and LCD.
FIR Analysis using ML for Proper Acts and Sections
Authors: Aslam Shaikh Nihalahamad
Published: February 2025

This project aims to enhance the filing process of First Information Reports (FIRs) by improving speed, accuracy, and
legal correctness. A critical aspect of FIR filing involves correctly applying the relevant sections of the Indian Penal Code (IPC)
and other applicable laws, as errors can significantly impact prosecution and justice outcomes.
To achieve this, the project emphasizes key objectives such as ensuring accuracy and completeness through an AI/ML system
that captures all necessary information while minimizing errors. Legal compliance is prioritized by adhering to established
requirements and standard FIR formats set by the IPC.
Interfaces entre a escrita e a oralidade nas aulas de lí­ngua materna: uma experiência com alunos do ensino fundamental
Authors: Oliveira Rose Maria Leite de , Dantas Wallace
Published: February 2025

O presente trabalho é fruto de um estudo realizado com alunos do Ensino Fundamental de uma escola particular da Paraí­ba. Seu foco foi investigar que estratégias linguí­sticas, textuais, cognitivas ou interacionais são utilizadas por aprendizes da lí­ngua ao lidarem com a produção de textos escritos tomando como base a fala espontânea. Para realizarmos tal investigação, tomamos como aporte teórico, os pressupostos de Marcuschi (2007),Travaglia (2006), Fávero et al. (2005), Cavalcante & Melo (2006), Monteiro-Platin (2008), dos PCNs (1998) dentre outros. Os resultados do estudo apontaram para o quanto é pertinente o trabalho com gêneros orais em sala de aula e sua interface com os textos escritos, como forma de contribuir para o desenvolvimento da competência comunicativa dos aprendizes da lí­ngua, haja vista que, em muitas das situações comunicativas do cotidiano, a fala é uma ferramenta imprescindí­vel para as ações de linguagem.
Práticas de letramento(s) na escola: reflexões sobre a formação do aluno do ensino médio
Authors: Abreu Kélvya Freitas
Published: February 2025

O presente estudo traz uma reflexão sobre o que se entende por letramento(s) e como esta abordagem pedagógica de ensino produz impactos na formação dos sujeitos aprendizes de lí­ngua materna no ensino médio. Nesse sentido, adotam-se os últimos direcionamentos propostos pelas Orientações Nacionais do Ensino Médio (OCNEM, BRASIL, 2006) e pela perspectiva do letramento, mais precisamente em sua vertente sociocultural (CASSANY, 2006), para a discussão e análise desta pesquisa. Uma vez que ao compreender os conceitos-chave que gravitam os estudos do(s) letramento(s), os docentes constroem espaços de consciência linguí­stica do usuário de linguagem nas mais diversas práticas, inclusive as escolares. Como resultado, o aluno se percebe envolto em uma contí­nua atividade de construção de sentidos, inserindo-os em práticas socioculturamente contextualizadas e situadas que os levam a oportunidade de construir, compartilhar, recriar e recontextualizar o seu conhecimento.