bluuebunny/crossref_metadata_2025 huggingface dataset:
TRATAMENTO DA DOENÇA PERIODONTAL E A INFLUÊNCIA DO TABACO NAS SUAS DIVERSAS FORMAS DE UTILIZAÇÃO.
Authors: Ribeiro Marco Antônio Ávila , Santos Frederico Augusto de Lima , Faustino Juliano , Gonçalves Lísia Aparecida Costa , Rocha Vinicio Felipe Brasil
Published: August 2023

Este trabalho teve como objetivo conhecer a respeito das diferentes formas de utilização do tabaco e suas repercussões no tratamento da doença periodontal, assim como apontar evidências disponíveis sobre seu aspecto microbiológico, o aconselhamento e tratamento interdisciplinar deste importante vício. Foi realizada uma revisão de literatura com buscas no Scielo, PubMed, Google acadêmico, sites científicos, livros e e-books, todos datados entre 2005 e 2020. Verificou-se que a associação entre o fumo e o biofilme modificado por este, contribuem para que a doença periodontal tenha uma evolução mais acelerada e de pior prognóstico. Concluiu-se que o profissional deve conhecer os mecanismos desencadeados pelo tabaco e a melhor forma de ajudar seus pacientes na diminuição deste uso ou cessação total. O profissional também deve saber lidar com pacientes com quadros depressivos ou aqueles que relatam dificuldade em parar de fumar, encaminhando esses pacientes para profissionais especializados.
MANEJO ODONTOLÓGICO EM TEMPOS DE COVID-19
Authors: Rodrigues Vitor Carvalho , Nunes Douglas Carlos , Pereira Rafael Martins Afonso , Pereira Patrícia Cristine de Oliveira Afonso , Marangon Júnior Helvécio
Published: August 2023

A adoção de medidas de prevenção e controle de infecção cruzada, dentro do consultório odontológico, é de inteira responsabilidade do cirurgião-dentista e sua equipe. Recentemente, a OMS declarou pandemia, em decorrência do vírus Sars-CoV-2, causador da doença COVID-19, de caráter respiratório, transmitida principalmente pela tosse e espirros, por contato direto com o portador infectado ou com secreções contendo o vírus. Os profissionais de Odontologia desempenham um papel crucial na prevenção da transmissão dessa infecção viral, pois aerossóis e gotículas são importantes meios de propagação. Dessa forma, o objetivo desse trabalho de cunho descritivo exploratório, foi realizar uma revisão de literatura sistematizada a respeito dos aspectos fisiopatogênicos, da conduta odontológica frente à COVID-19, suas rotas de transmissão e possíveis sinais e sintomas, bem como descrever os métodos de prevenção e controle da infecção na prática odontológica. Artigos completos publicados em língua inglesa, indexados em bases de dados e que abordavam protocolos para práticas odontológicas, foram incluídos nessa revisão. Selecionou-se 47 artigos, sendo que destes, 30 foram incluídos no estudo. Verificou-se que, é unânime a indicação do estabelecimento de protocolos de manejo clínico a serem instituídos nos consultórios odontológicos e de fundamental importância aos cirurgiões-dentistas e sua equipe. O conhecimento técnico e a conscientização acerca da COVID-19 tornam-se estratégias eficazes para o controle e gerenciamento da sua propagação.
ABORDAGEM CLÍNICA E TERAPÊUTICA DOS EFEITOS COLATERAIS CAUSADOS PELA RADIOTERAPIA EM CABEÇA E PESCOÇO
Authors: Oliveira Amanda Alves de , Maluf Fabiano
Published: August 2023

O objetivo do artigo é apresentar os impactos e efeitos colaterais que a radioterapia de cabeça e pescoço pode trazer para o paciente oncológico com ênfase nos principais efeitos adversos, suas características e consequências na mucosa oral, além de ressaltar a importância da atuação do cirurgião-dentista no diagnóstico, terapêutica e cura. Trata-se de estudo de natureza exploratória e descritiva por meio de revisão integrativa de literatura no qual os dados foram analisados por meio de busca em base de dados. Foram encontrados 96 artigos sobre o tema e selecionados dez artigos para compor a amostra. Os efeitos colaterais mais frequentemente relatados foram: xerostomia, osteorradionecrose, trismo, mucosite, disgeusia, cáries de radiação e infecções oportunistas. Os dados mostraram que as sequelas da radioterapia se estabelecem rapidamente após o início do tratamento e demoram a desaparecer comprometendo a saúde bucal como um todo. Dessa forma, a terapia preventiva, iniciada antes da radioterapia, reduz as chances do surgimento e agravo dos efeitos colaterais e o cirurgião-dentista é capaz de tratar e amenizar as consequências proporcionando aos pacientes qualidade de vida.
Using neural networks to predict the low curves and processing maps of TNM-B1
Authors: Stendal Johan Andreas , Emdadi Aliakbar , Sizova Irina , Bambach� Markus
Published: August 2023

The ability to predict the behavior of a material is vital in both science and engineering. Traditionally, this task has been carried out using physics-based mathematical modeling. However, material behavior is dependent on a wide range of interconnected phenomena, properties and conditions. During deformation processes, work hardening, softening, microstructure evolution and generation of heat all occur simultaneously, and can either cooperate or compete. In addition, they can vary with the deformation temperature, applied force and process speed. As the complete picture of material behavior from the macroscopic scale to the atomic scale is not yet fully understood, deformation processes such as hot forg-ing can be difficult to handle using physics-based modeling. Usually, modeling the high temperature deformation behavior of metals consists of extracting characteristic points from the experimental flow curve data, and use them to fit the model equations through regression analysis. This is called phenomenological modeling, as it is based on the observations of a phenomena rather than being derived from fundamental theory. Alternatively, the data obtained from experiments could be used for a data-driven or machine learning (ML) approach to model the material behavior. An ML model would require no knowledge of the underlying physical phenomena governing a deformation process, as it can learn a mapping function which connects input to output based purely on the experimental data. In this work, the application of machine learning to modeling the flow curves of two different states of the titanium aluminide (TiAl) TNM-B1; hot isostatically pressed (HIPed) and heat treated, is investigated. Neural networks were used to learn a mapping function which predicted flow stress based on the inputs temperature, strain and strain rate. In addition, strain rate sensitivity maps and processing maps based on the experimental and the predicted data are analysed and compared. The results revealed that the neural networks were able to produce realistic and accurate flow curves, which fitted to the underlying behavior of the experimental data rather than the noise. The strain rate sensitivity and processing maps showed conflicting results. Good correlation was found for the HIPed material state between the ones based on experimental data and the ones based on predicted values, while there was a significant difference for the heat treated state.
Gases in the near-surface zone of the reclaimed Barycz municipal waste landfill – a case study from southern Poland
Authors: Kopera Paulina A. , Sechman Henryk , Twaróg Anna
Published: August 2023

The formation of biogas at municipal landfills and the significant emission of greenhouse gases from these facilities into the environment were the main reasons for analyzing the molecular composition of soil gas in the near-surface zone at the reclaimed part of the Barycz municipal waste landfill. The relations between the studied components (methane, carbon dioxide, light hydrocarbons and non-hydrocarbon components) and impact of the magnitude of recorded concentrations of methane and carbon dioxide on their emission to the atmosphere were evaluated. Two profiles were determined, along which 41 soil and landfill gas samples were taken at 20-meter intervals. At the same time, emissions were measured at each sampling point using a static chamber with a portable fluxometer. Chromatographic analysis showed that the concentrations of methane and carbon dioxide fluctuated in the ranges: 2.1 ppm – 76 vol% and 0.04 ppm – 11 vol%, respectively. Relatively high concentrations of these gases were determined at many of the measurement points, and this was particularly evident at the A-A’ profile, indicating stronger biochemical processes in this part of the landfill, or lateral migration of methane from the neighbouring stage II of the landfill, where biogas extraction is currently taking place. In addition, significant correlations between methane, carbon dioxide, and oxygen were demonstrated, indicating ongoing methane fermentation processes. Based on the study, it can be concluded that the southern part of the A-A’ profile is an optimal place to locate a degassing well from which biogas production could be used. However, the research is only preliminary and, it will be necessary to extend the soil gas tests before the final decision on the location of the well is made. Moreover, it has been shown that the concentrations of methane and carbon dioxide measured at points located outside the landfill were low. This means that generated biogas probably does not migrate beyond the boundaries of reclaimed waste landfill, but this will need to be confirmed by performing additional soil gas tests inside and outside the landfill area. The preliminary assessment of the effectiveness of the reclamation carried out was confirmed by the negligible values of the measured methane and carbon dioxide emissions on the surface.
Integration of seismic and well data for a 3D model of the Balkassar anticline (Potwar sub-basin, Pakistan)
Authors: Mudasir Muhammad , Wysocka Anna , Naseem Shazia
Published: August 2023

The Potwar sub-basin is an important hydrocarbon producing zone of the Upper Indus basin and has significant oil and gas potential. The Balkassar area is the main oil field of the Potwar sub-basin and oil is mainly produced from Eocene carbonates. The Chorgali Formation is of Eocene age and is the main reservoir rock in this area. Structurally, the Potwar sub-basin is complicated, and surface features often do not reflect subsurface structures. This is due to the presence of detachments at different levels. In such cases, it is necessary to integrate seismic data with geological information for an accurate delineation of subsurface structures. Eleven seismic profiles were interpreted to understand subsurface structural style. To correlate well data with seismic data, a synthetic seismogram has been generated. Time, velocity and depth contour maps have been prepared. A 3D model for the Chorgali Formation has been prepared which confirms that this is a four-way anticlinal structure bounded by faults. It makes this structure more favorable for hydrocarbon accumulation. Moreover, a cross section has been prepared for five wells to show that the Chorgali Formation is spreading. Based on it, to show the relationship between compressional tectonics and basement slope, a 3D structural model has been prepared. In this case study, the Balkassar anticline was interpreted as a four-way closure pop-up structure which provides a structural trap for the accumulation of hydrocarbons. This study will help us understand the accumulation of hydrocarbons in the same type of structural traps in the Potwar sub-basin and in similar kinds of basins. It is also relevant to oil exploration within Pakistan.
Alunogen from the sulfate efflorescence of the Stone Town Nature Reserve in Ciężkowice (the Outer Carpathian Mountains, Poland)
Authors: Marszałek Mariola , Gaweł Adam
Published: August 2023

Alunogen (Al2(SO4)3∙17H2O), a rare secondary mineral, has been found in the efflorescence on sandstones from the Stone Town Nature Reserve in Ciężkowice, southeastern Poland. This is probably the first find of this salt on such rocks in Poland. Alunogen forms in various geological environments, but mainly from the oxidation of pyrite and other metal sulfides in ore deposits and Al-rich Earth materials under low-pH conditions. Its crystallization at this particular site depends on a set of necessary physicochemical (pH, concentration), climatic (season, temperature, humidity), site-related (location and protection of efflorescence), and mineralogical (the presence of pyrite) conditions. This paper presents the mineralogical and geochemical characteristics of the alunogen from the Stone Town Nature Reserve (based on SEM-EDS, XRPD, EPMA and Raman spectroscopy methods) as well as of the efflorescence itself (based on XRPD and STA coupled with QMS and FTIR for the analysis of gas products). Crystals of alunogen take the shape of flakes, often with a hexagonal outline, clustered in aggregates forming a cellular network. Its calculated formula is (Al1.96Fe3+0.01)Σ1.97(SO4)3∙17H2O (based on 12 O and 17 H2O). The unit-cell parameters refined for the triclinic space group P1 are: a = 7.423 (1) Å, b = 26.913 (5) Å, c = 6.056 (1) Å, a = 89.974 (23)°, b = 97.560 (25)°, g = 91.910 (22)°. The Raman spectra (SO4) bands are: intensive 995 cm−1 (ν1); low-intensive 1069, 1093 and 1127 cm−1 (ν3); low-intensive 419 and 443; medium-intensive 470 cm−1 (ν2); and medium-intensive 616 cm−1 (ν4). Those at 530, 312 and at 338 cm−1 are assigned to water vibrations and those at 135, 156, 180 cm−1 to the lattice modes. Although the efflorescence contained an admixture of other minerals (pickeringite, gypsum and quartz), the predominant alunogen is almost chemically pure and the above parameters are consistent with the values reported in the literature for alunogen from different locations and of various origins.
3D Block Modelling of the Sin Quyen IOCG Deposit, North Vietnam
Authors: Duong Van Hao , Nguyen Chau Dinh , Klityński Wojciech , Zygo Władysław , Nowak Jakub
Published: August 2023

The IOCG Sin Quyen deposit is located in the Red River shear zone of North Vietnam. The ore bodies are known as hydrothermal veins and are hosted in Proterozoic metapelite. A block modelling approach was used to build a 3D model of the ore bodies. An analysis was carried out on SurferR 11 computer software using the archival data recorded from several dozen boreholes distributed within the study area, as well as data obtained from the mineral and chemical analysis of 50 samples collected recently in the deposit. The ore bodies generally trend in a NW-SE direction with an average azimuth of 107° and a dip of around 70°.  Cu content in the ore bodies is inhomogeneous. In the bed extension direction, the exponential correlation of Cu concentration in ore bodies is recognized within 2,500 m, while in the direction perpendicular to the bed strike, the exponential dependence is observed at 500 m of distance. The high-grade mineralisation of copper within the ore bodies is often at the altitude interval from ∼100 m to ∼150 m above sea level (asl). These bodies are also rich in uranium and gold-bearing minerals. The total resources of Cu, U and Ag were estimated and amounted to 361,000; 12.7 and 11.87 tonnes respectively. The model indicates the downward extension of some ore bodies to below 300 m beneath the ground surface.
Recognition of the flysch substrate using the electrical resistivity tomography (ERT) method to assess the effectiveness of the injection process
Authors: Ćwiklik Michał , Pasierb Bernadetta , Porzucek Sławomir
Published: August 2023

During the construction of a section of the S-7 Lubień – Rabka-Zdrój dual expressway, located in the area of the Carpathian flysch (Carpathian Flysch Belt, South Poland), damage to the embankment was observed, as well as cracks and depressions in the new pavement. An analysis of the geological and engineering conditions in the area of the road section under construction showed the existence of a complex tectonic structure of the flysch formations, a shallow groundwater table, and numerous landslides. In order to stabilize the road substrate, it was decided to carry out injections, and the locations of these injections were initially geotechnically tested. However, due to the high variability of the geological structure, the target method employed was electrical resistivity tomography (ERT), which performed the survey in two stages. In Stage I, the geoelectrical/geochemical structure of the near-surface zone was identified, and the probable causes of road damage were indicated. This stage was completed by performing the stabilization and sealing process of the ground with an injection mixture. In Stage II, studies were carried out to evaluate the effectiveness of the injection process. The ERT method effectively identified the shallow geological structure and, in particular, delineated the zone of strong fractures in the flysch and areas associated with faults. Using the electrical resistivity tomography method, it was also possible to determine the injection mixture’s approximate penetration depth and the loosening zone’s degree of filling.
Opposing chemosensory functions of closely related gustatory receptors
Authors: Ahn Ji-Eun , Amrein Hubert
Published: August 2023

Most animals possess functionally distinct population of taste cells, expressing receptors that are tuned to compounds of different valence. This organizational feature allows for discrimination between chemicals associated with different taste modalities and facilitates sensing of foods contaminated with toxic chemicals. In the fruit fly
D. melanogaster
, primary sensory neurons express taste receptors that are tuned to distinct chemicals, thereby activating neural ensembles that elicit either feeding or avoidance behavior. Members of a family of ligand gated receptor channels, the Gustatory receptors (Gr), play a central role in these behaviors. In general, closely related, evolutionarily conserved Gr proteins are co-expressed in the same type of taste neurons, tuned to chemically related compounds and therefore triggering the same behavioral response. Here, we report that members of the Gr28 subfamily are expressed in largely non-overlapping sets of taste neurons in
Drosophila
larvae, detect chemicals of different valence and trigger opposing feeding behaviors. We determined the intrinsic properties of
Gr28
neurons by expressing the mammalian Vanilloid Receptor (VR1), which is activated by capsaicin, a chemical to which wild type
Drosophila
larvae do not respond. When VR1 is expressed in
Gr28a
neurons, larvae become attracted to capsaicin, whereas expression of VR1 in
Gr28bc
neurons triggers avoidance to capsaicin. Thus, the
Gr28
proteins, which have been evolutionarily conserved over the last 65 million years in insects, represent the first taste receptor subfamily in which specific members mediate behavior with opposite valence. We also identified denatonium benzoate, a synthetic bitter compound that shares structural similarities with natural bitter chemicals, as a ligand for a receptor complex containing a Gr28bc or Gr28ba receptor subunit. Alphafold structure prediction, combined with the limited sequence conservation in the putative binding pockets of various Gr28 proteins, creates a theoretical framework for targeted
in vivo
structure function studies to precisely map residues critical for ligand recognition.
Integrative models of histopathological images and multi-omics data predict prognosis in endometrial carcinoma
Authors: Li Yueyi , Du Peixin , Zeng Hao , Wei Yuhao , Fu Haoxuan , Zhong Xi , Ma Xuelei
Published: August 2023

Objective

This study aimed to predict the molecular features of endometrial carcinoma (EC) and the overall survival (OS) of EC patients using histopathological imaging.

Methods

The patients from The Cancer Genome Atlas (TCGA) were separated into the training set (n = 215) and test set (n = 214) in proportion of 1:1. By analyzing quantitative histological image features and setting up random forest model verified by cross-validation, we constructed prognostic models for OS. The model performance is evaluated with the time-dependent receiver operating characteristics (AUC) over the test set.

Results

Prognostic models based on histopathological imaging features (HIF) predicted OS in the test set (5-year AUC = 0.803). The performance of combining histopathology and omics transcends that of genomics, transcriptomics, or proteomics alone. Additionally, multi-dimensional omics data, including HIF, genomics, transcriptomics, and proteomics, attained the largest AUCs of 0.866, 0.869, and 0.856 at years 1, 3, and 5, respectively, showcasing the highest discrepancy in survival (HR = 18.347, 95% CI [11.09–25.65], p < 0.001).

Conclusions

The results of this experiment indicated that the complementary features of HIF could improve the prognostic performance of EC patients. Moreover, the integration of HIF and multi-dimensional omics data might ameliorate survival prediction and risk stratification in clinical practice.
Factors Affecting Recidivism of Persons Deprived of Liberty at Tabaco City District Jail
Authors: Onsat Desman , Breva Jr. Domingo
Published: August 2023

Recidivism is a term used to describe the tendency of a person who has been released from prison or other Detention facilities to re-offend and return to incarceration. The study aimed to identify the factors that affect the recidivism of persons deprived of liberty at Tabaco City District Jail using a descriptive-quantitative research design. The data were collected through a survey questionnaire administered to 100 selected PDL who were detained or had been released and returned to the jail. The study found several factors contributing to recidivism, including lack of employment opportunities, substance abuse problems, lack of education and skills, and poor social support. The findings suggest the need for more comprehensive rehabilitation and reintegration programs that address these underlying factors to reduce the likelihood of repeated offenses and promote successful re-entry into society. These programs should focus on providing educational and vocational training, substance abuse treatment, and social support to help PDL successfully reintegrate into their communities. This is useful for policymakers and practitioners in the criminal justice system to develop and implement more effective interventions to reduce recidivism rates among persons deprived of liberty at Tabaco City District Jail.
Condições Higiênico-Sanitárias em uma Fábrica de Farinha de Mandioca no município de Castanhal-PA avaliação e recomendações
Authors: E Oliveira Jose Moises de Oliveira , Santos Bueno Roger da Silva , De Lima Suely Cristina Gomes
Published: August 2023

No beneficiamento da mandioca, são identificados desafios como instalações em péssimo estado de conservação e falta de aplicação de medidas higiênico-sanitárias. Este trabalho teve como objetivo avaliar o processo produtivo da farinha de mandioca em uma agroindústria localizada na zona rural de Castanhal-PA, e propor melhorias de acordo com as Boas Práticas de Fabricação (BPF). Para isso, foi realizado um checklist de BPF, que possibilitou a avaliação sanitária por meio do cálculo da porcentagem de conformidade. Com base nessa análise, a indústria foi classificada no grupo 3, apresentando 50,43% de conformidade, com índice mais baixo relacionado à documentação. Também foi aplicado um questionário aos colaboradores  para avaliar o conhecimento deles sobre as BPF. Com base nesses resultados, um curso foi ministrado, no qual foi utilizado um folder infográfico que abordava os principais pontos de dúvida identificados no questionário. Além disso, foi elaborado um plano de ação contendo recomendações de melhorias para a agroindústria, com foco principalmente na infraestrutura do estabelecimento, visando evitar contaminações cruzadas. A implementação das medidas propostas têm como objetivo a melhoria das condições  higiênico-sanitárias  na fabricação da farinha, garantindo um produto seguro para o consumidor.
An assessment of the Impact of Good Governance on Health Outcome among Selected African Countries
Authors: Shafa Musa Ismail , Haladu Adahama Ibrahim , Salisu Ali
Published: August 2023

Good governance is an essential component that drives better health outcome and education output required as a catalyst that will stimulate economic growth, and this constitutes a vital social objective as a result of good level of human capital development. The study evaluated the impact of good governance on health outcome among selected African countries using panel data from 2000 to 2020. The Panel unit root tests indicated that real gross domestic product, health outcome, and indicators of good governance are stationary at level while health expenditure and foreign aid are stationary at first difference. The Generalized Method of Moment (GMM) results show that indicators of good governance have positive and statistically significant effects on health outcome in the selected African Countries. Real gross domestic product has a positive and a statistically significant effect on health outcome in the selected African Countries Life expectancy has a positive and statistically significant effect on health outcome in the selected African Countries. Health expenditure has a positive and statistically significant effect on health outcome in the selected countries. Foreign aid has a positive and statistically significant effect on health outcome in the selected African Countries. The study recommends that African Countries should ensure that indicators of good governance such as political stability, accountability and voice, and control of corruption are moving smoothly without any interruption, by so doing economic growth of African countries will increases.
Spatial Assessment of Elevation-based Flood Risk Level of Communities and Mitigation Measures in the Wetlands Areas of Rivers and Bayelsa States, Niger Delta Region, Nigeria
Authors: Horsfall G. B. , Obafemi A. A. , M. Ogoro
Published: August 2023

The study examined the spatial assessment elevation-based flood risk level of communities and mitigation measures in the wetlands areas of Rivers and Bayelsa States, Niger Delta Region, Nigeria. The study made use of the elevation data from the Shuttle Radar Topographic Mission, flood height and tidal inundation data to determine the flood risk levels of communities in the study location. Similarly, 400 copies of questionnaire were administered to the residents from the wetland communities using random sampling technique. Descriptive and inferential statistics were used for the analysis. Findings revealed that majority of the coastal region in the study area is generally low lying and highly exposed to flood event. Results also showed that most communities in the Ogba/Egbema/Ndoni Local Government Areas are very highly exposed which included Ahoada, Azagbene, Eben, Kpopkie, Owenegbene, Bisagbene, Ekeni among others while the very risk exposed communities included Okpogo, Ebubu, Aboigbene among other. Findings showed that damage compensation and government relief funds were the major ways used to tackle the negative impact of flood. The popular methods of flood abatement in the study area were restoring meanders in brooks and rivers and coastal wetlands protection. The study concluded that many communities in the coastal parts of Rivers and Bayelsa States in the Niger Delta Region of Nigeria are highly prone to flood risk. The study recommended among others that the use of dam for flood abatement and prevention should be adequately established in the study area; and apart from embankment, other flood defense and control measures such as flood barrier, mobile flood wall, coastal sand supply, bypasses to safeguard wetlands, connect rivers to existing lake, dredging rivers, and river bed widening should be adequately put in place to reduce the levels of flood impact in the study area.
Assessment of the Effect of West African Ebony (Diospyros mespiliformis) Seed Extracts on Selected Bacteria of Upper River Benue Surface Water
Authors: Mohammed Mohammed A. , Bukar Modu A.
Published: August 2023

This study was conducted to investigate the effects of D. mespiliformis; crude seed, mucilage and seed extracts on some surface water quality parameters and total bacteria count. The experiment was design as a factorial experiment in Complete Randomized Design (CRD). Sample water was collected from Upper River Benue in Jimeta Bridge. D. mespiliformis purchased at Jimeta Market, Yola Adamawa State. The water sample was collected in Jerry cans (50 litters) transported to wet laboratory, Department of Fisheries, School Agriculture, Modibbo Adama University of Technology Yola where the following physico-chemical parameters were analyzed Electrical Conductivity, Total Dissolve Solid, Ionic Concentration, Temperature, Biological Oxygen Demand and Turbidity. However, Total Bacterial Count was analyzed from microbiology laboratory of same University. Data obtained were analyzed using Analysis of Variance (ANOVA). Result obtained shows the effect of D. mespiliformis treated surface water on the Physicochemical Parameters and effect of D. mespiliformis Crude Seed, Mucilage and Seed Extracts on Total Bacteria Count. The following bacteria Escherichia coli, Bacillus subtilis and Staphylococcus aureus were used during the studies with E. coli has highest total bacteria count of 233 and 22 recorded lowest in seed extract, B. subtilis recorded it highest of 164 and 42 reveal as lowest in the seed mucilage while S. aureus has highest of 100 with it lowest of 32 recorded in mucilage. Further study on the efficacy of D. mespiliformis crude seed, mucilage and seed extracts on contaminant water treatment should be done.
Effect of Different Herbicidal Weed Management on Yield and Economic of Ragi
Authors: Kumar Harendra , Tiwari Nitish , Savu Rama Mohan , Langangmeilu Golmei , Chandrakala
Published: August 2023

The present experiment was carried on the performance of ragi at the Instructional cum Research Farm, Indira Gandhi Krishi Vishwavidyalaya, Raipur, Chhattisgarh during Kharif seasons  2021 and 2022 The field experiment was laid out of ragi (Indira ragi 1) was growing  variety for test crop in Randomized block design (RBD) with 10 treatment and 3 replications. The crop was sown manually on seedcum fertilizers 1 July 2021 and 2 July 2022 after the onset of monsoon. The result of the experiment revealed that, different weed management practices on seed yield, straw yield, harvest index % and economics of different herbicide application of ragi reveals that T9: Green manuring up to 40 DAS required highest cost of cultivation (Mean viz., 39676Rs. ha-1) than hand weeding twice 20 and 40 DAS (Mean viz., 34876Rs. ha-1) and lowest cost of cultivation in control (Mean viz., 22876Rs. ha-1). Gross return, net return and B: C ratio was significantly higher under (T5) Pyrazosulfuron ethyl 10 % 20 g/ha (PE) fb Chlorimuronethyl 10 % + Metsulfuron methyl 10 % 4 g/ha (PoE). Seed and straw yield of finger millet (Mean viz., 2719 and 8167 kg ha-1   and 24.98%), Gross return, net return and B: C ratio (Mean viz., 94573, 68950Rs. ha-1 and 3.69) while minimum was recorded under T10: control during both years and on mean value.
Effects of Integrated Nutrient Management on Soil Properties, Growth and Yield of Black Gram (Vigna mungo L.) var. Shekhar-2
Authors: Goswami Anal , Bharose Ram , Thomas Tarence , Naga Indar Raj
Published: August 2023

A field experiment was conducted at research farm of Department of Soil Science and Agricultural Chemistry, SHUATS, Prayagraj, (U.P.) on sandy loam soil to Assess the “Effects of Integrated Nutrient Management on Soil Properties, Growth and Yield of Black gram (Vigna mungo L.) var. Shekhar-2” during Zaid season of 2022. The experiment consists of nine treatment combinations, comprised in randomized block design with three replications. To achieve higher growth and yield it was found application of T9 (RDF + 100% Rhizobium + 100% Biochar) has shown effective growth under Prayagraj climatic conditions. It was observed that for physical and chemical properties of soil in treatment T9 (RDF + 100% Rhizobium + 100% Biochar) were improved significantly due to the application of Nitrogen, Phosphorus, Potassium, Rhizobium and Biochar inputs. Bulk density (Mg m-3), Particle density (Mg m-3), Pore space (%), Water holding capacity (%), pH, Electrical conductivity (dS m-1), Organic carbon (%), Available Nitrogen (kg ha-1), Available Phosphorus (kg ha-1), Available Potassium (kg ha-1). The soil organic carbon content, Water holding capacity and available NPK significantly increased in most of the treatments after harvest of Black gram, it was observed that treatment T9 (RDF + 100% Rhizobium + 100% Biochar) was best in terms of growth, yield and economic parameters with maximum plant height, the number of branches plant-1, seeds pod-1, pod yield and maximum cost benefit ratio.
Genetic Inheritance of Anthocyanin Pigmentation in Rice (Oryza sativa L.)
Authors: Manoj M. S. , Surendra P. , Bharatkumar Chitti , Nandini B. , Manju M. J. , Hosmath J. A.
Published: August 2023

Rice is an important cereal crop that belongs to the grass family Poaceae. A unique feature of purple-coloured anthocyanin pigmentation is possessed by some of the rice varieties and the accumulation of anthocyanin in plants offers resistance to UV radiation and brings out responses to various biotic and abiotic stresses. Knowledge of the inheritance of pigmentation will aid breeders in developing appropriate selection strategies to improve the trait under consideration. In order to study the inheritance of anthocyanin pigmentation, an experiment involving the F1 and segregated F2 populations obtained by crossing the two Oryza sativa subsp. indica varieties, viz., BPT-5204 (non-pigmented) and HY-256 Purple (pigmented), was conducted during three consecutive growing seasons at AICRIP, ARS (Paddy), Sirsi. Hybridization between the female parent, BPT-5204 and male parent, HY-256 Purple, was done during summer 2021 and the seeds obtained from hybridization constituted the F1 generation and were sown during kharif 2021. The same were subjected to selfing to obtain seeds to generate the F2 population, which were evaluated along with the parents and F1 plants during summer 2022. Observations on the presence or absence of anthocyanin pigmentation for different morphological traits, viz., leaf blade, leaf tip, leaf margin, midrib, juncture and junctura back, were recorded in the parents, F1’s and F2 populations in such a way that the presence of pigmentation was recorded as purple, while its absence was recorded as non-pigmented or green. Purple-coloured anthocyanin pigmentation was absent in all the characters in the F1 plant. Similarly, varied segregation for pigmentation was observed and documented in 1276 plants that constituted the F2 generation. The data was analyzed for colour pigmentation to determine the fitness with diverse segregation ratios and to determine the mode of inheritance by chi-square test, which revealed the involvement of two to three genes with different gene interactions.
Health Implication of Mycotoxigenic Fungi and Mycotoxins Analysed from Sun Dried Yam and Potato Chips Sold in Minna Niger State, Nigeria
Authors: Evuti Mahmud Mohammed , Galadima Musa , Makun Hussaini Anthony , Badmos Fatimah Omolola , Unekwuojo Ajanya Benjamin , Friday Attah , Hamidu Abdullahi
Published: August 2023

Mycotoxin is toxic secondary metabolite synthesized by filamentous fungi during their stationary phase of growth in agricultural crops, food and feed products. Niger State experienced high temperature and humidity for about three-quarters of the year, and these are some of the conditions that encourage filamentous fungi to produce mycotoxin in food products. Enzyme Linked Immunosorbent Assay (ELISA) was used to dectect mycotoxins. Mycological profile and mycotoxins of sun dried yam and potato chips was determined. Total of fifty (50) samples were collected randomly from five markets in Minna and its environs. 179 isolates were recorded. Aspergillus species 86(53.1 %) Mucor species 27(15.1 %), yeast species 25(13.9 %) Penicillium species 14(7.8 %), Fusarium species 14(7.8 %) Rhizopus species 3(1.7 %) and Microsporum species 1(0.6 %) were the common fungi. The highest mean fungal counts (12.8 x 103 cfu/g) were observed in sweet potato chips bought in Gwada market while the lowest (3.5 x 103 cfu/g), was observed in Yam chips from Paiko market. The mean moisture content of 7.41±2.28 % was recorded in potato chips and yam chips had the lowest moisture content of 4.72± 1.66 %. Total aflatoxins, fumonisin and zearalenone contents were detected in 48 (96 %) of the samples. In yam and potato chips, total aflatoxin contamination was 68 and 84 % with mean concentrations of 12.6±7.36 μg/kg and 10.3±13.81 μg/kg respectively. The total aflatoxin concentration range of yam and potato chips were 0-61.84 μg/kg and 0-54.49 μg/kg with 28 and 48 % of the samples below 4μg/kg E.U limit respectively. Fumonisin contamination was 80 and 60% with mean concentrations of 928.123±559.50 μg/kg and 722.64 ± 137.85 μg/kg with a range 0.0-4018.24 μg/kg and 0 – 2055.98 μg/kg and had 52 and 72 % below 1000 μg/kg acceptable limit for yam and potato chips respectively. Zearalenone contamination in yam and potato account for 56 and 68% having mean concentration of 16.33± 9.71 μg/kg and 24.12± 21.03 μg/kg with a range 0 – 45.53 μg/kg and 0 – 83.74 μg/kg respectively. All the samples contaminated with Zearalenone were below the E.U regulatory limit of 100 μg/kg for food stuff intended for direct consumption. Dietary exposure and risk characterisation (EDI and %TDI) were further estimated for total aflatoxins, fumonisin and zearalenone. It was concluded that the level of contamination of these chips with mycotoxins poses a serious threat to public health and there is the need for proactive approach to drastically reduce fungal contamination.
Thermosonication an Alternative to Thermal Pasteurization for Nagpur Mandarin Juice
Authors: Sahu Rajnish Kumar , Minj Shashi Kiran , Sahu Pooja
Published: August 2023

Nagpur mandarin is well known globally for its excellent nutritional benefits and flavour. These all characteristics get affected due to a lack of knowledge & processing techniques. Thermal pasteurization is a processing technique mostly used for juice processing before storage. Thermal pasteurization treatment leads to a loss in various physicochemical qualities of juice viz. ascorbic acid content, and carotenoid content. Thermal pasteurization treatment also leads to an increase in limonin content and the browning value of the juice. Therefore, an experiment was carried out to check the effect fascorbic acid and carotenoid content using the ultrasound combined with higher temperatures known as ensthermosensation on Nagpur mandarin (Citrus reticulata Blanco) juice as compared. Treatments were also used to observe its effect on limonin, browning, total soluble solids, pH & acidity as compared to thermal pasteurization. Juice samples were thermosonicated at temperatures of 50 ℃, 55 ℃, 60 ℃, and 63 ℃ for 25, 20, 15 and 10 min respectively at a constant frequency of 40 kHz. Juice samples were also thermally pasteurized at 65 ℃, 75 ℃, 85 ℃, and 95 ℃ for 80, 60, 40, and 20 sec. Samples were analyzed after treatment. Thermosonication treatments showed better ascorbic acid content and carotenoid content in comparison to thermally pasteurized juice samples. Limonin value and browning value were also less in thermosonicated juice samples. Both treatments do not have any significant effect on Physicochemical characteristics like TSS, pH & acidity. fromThe result indicated that ensthermosensation treatments performed better than thermal pasteurization treatments and can be used as an alternative technique for Nagpur mandarin juice processing.
I Cancervive: Exploring the Modern Travails of Cancer-Stricken Adolescents in the Pandemic New Normal
Authors: Adlawan Melvel Angelo M. , Agbon Essa P. , Monzolin Jorissa A. , Ceballo Emma C.
Published: August 2023

Currently, the world faces two critical challenges: the COVID-19 pandemic and surging cancer cases. Healthcare systems worldwide, including the Philippines, struggle to cope with rising cancer patient mortality. Urgent action and innovative solutions are vital to managing cancer care amidst the ongoing pandemic. Hence, this study explored the journey of adolescent cancer patients who are receiving treatment during the pandemic particularly the present challenges with cancer treatment, its holistic repercussions, the patient's coping mechanisms, and their significant life breakthroughs. It employed a qualitative multiple-case study, utilizing semi-structured interviews to collect data from four (4) pediatric hematology-oncology cases. The data was analyzed using content analysis wherein the narratives of the participants were compared. The findings of the study revealed themes that represent the challenges experienced by cancer patients namely, (1) treatment and other medical services disruption; (2) reduced social support; and (3) increased contamination-related anxieties. The immediate repercussions included (1) psychological disturbance, stress, and depression; (2) uncertainty and emotional distress; (3) stronger behavioral adherence to COVID-19 prevention measures; (4) increased gadget usage/gadget dependence, and (5) decreased scholastic involvement. Further, the participants’ coping mechanisms include (1) active coping strategies via engaging activities; (2) awareness and acceptance of the current situation; (3) strong social and spiritual support, and (4) positive and active mind setting. The insights gathered from the analysis are (1) the need for better access to cancer-related services and assistance, and (2) the call for more psychological health intervention programs. The findings showed that the insights and realizations of participants emphasized the need for better access to cancer-related services and assistance and a calling for psycho-oncological therapeutic interventions for fellow cancer patients.
Search Engine Optimization (SEO) for Journalistic Content in Building Brand Image for Innovation Products
Authors: Goenawan Felicia , Hadi Ido Prijana , Sidik Amelia
Published: August 2023

The product innovations produced by Meal for 60+ focused on healthy food for the elderly. The purpose of Meal for 60+ is as a medium that can help everyone, be it mothers, fathers, teenagers, and children, in serving healthy food for the elderly at home. It is not easy for people to accept an innovative product. Companies must be able to build a Brand Image for their innovative products in the eyes of potential consumers. Therefore, the purpose of this research is to find out what factors are in the diffusion of innovative products and can be used to create messages on websites and Instagram. The paradigm in this research is positivistic with a quantitative approach and the research method used is a survey. The distribution of the questionnaire focused on respondents in Solo and Tulungagung. The results of this study indicate that Meal for 60+ should be more aggressive in conveying information related to their products. This is because respondents need acceptance from the surrounding community first before accepting innovative products. The keyword "healthy diet menu" is the main reference for respondents in searching for news. “HEREDITY.ID” will be one of the portal websites that can be accessed by the public, accommodates and becomes a source of detailed information on patent products in Indonesia.
Supplemental Nutrition Assistance Program Emergency Allotments and Food Security, Hospitalizations, and Hospital Capacity
Authors: Lavallee Matthew , Galea Sandro , Abuelezam Nadia N.
Published: August 2023

Importance

Understanding how social policies shape health is a national priority, especially in the context of the COVID-19 pandemic.

Objective

To understand the association between politically motivated changes to Nebraska’s Supplemental Nutrition Assistance Program (SNAP) policy and public health measures during the COVID-19 pandemic.

Design, Setting, and Participants

This cross-sectional study used synthetic control methods to estimate the association of Nebraska’s decision to reject emergency allotments for the SNAP with food security and hospital capacity indicators. A counterfactual for Nebraska was created by weighting data from the rest of the US. State-level changes in Nebraska between March 2020 and March 2021 were included. Data were acquired from the Census Bureau’s Household Pulse Survey on individual food security and mental health indicators and from the US Centers for Disease Control and Prevention on hospital-level capacity indicators. Data analysis occurred between October 2022 and June 2023.

Intervention

The rejection of additional SNAP funds for low-income households in Nebraska from August to November 2020.

Main Outcomes and Measures

Food insecurity and inpatient bed use indicators (ie, inpatient beds filled, inpatient beds filled by patients with COVID-19, and inpatients with COVID-19).

Results

The survey data of 1 591 006 respondents from May 2020 to November 2020 was analyzed, and 24 869 (1.56%) lived in Nebraska. Nebraska’s population was composed of proportionally more White individuals (mean [SD], 88.70% [0.29%] vs 78.28% [0.26%]; P < .001), fewer individuals who made more than $200 000 in 2019 (4.20% [0.45%] vs 5.22% [0.12%]; P < .001), and more households sized 1 to 3 (63.41% [2.29%] vs 61.13% [1.10%); P = .03) compared with other states. Nebraska’s rejection of additional funding for SNAP recipients was associated with increases in food insecurity (raw mean [SD] difference 1.61% [1.30%]; relative difference, 19.63%; P = .02), percentage of inpatient beds filled by patients with COVID-19 (raw mean [SD] difference, 0.19% [1.55%]; relative difference, 3.90%; P = .02), and percentage of inpatient beds filled (raw mean [SD] difference, 2.35% [1.82%]; relative difference, 4.10%; P = .02).

Conclusions and Relevance

In this cross-sectional study, the association between social policy, food security, health, and public health resources was examined, and the rejection of emergency allotments in Nebraska was associated with increased food insecurity. Additionally, this intervention was associated with an increased rate of hospitalizations for COVID-19 and non–COVID-19 causes.
Using Machine Learning to Predict Suitability for Surgery at an Ambulatory Surgical Center
Authors: Henderson James , Cuttitta Anthony , Dossett Lesly A.
Published: August 2023

This Surgical Innovation describes the use of a site optimization model that uses machine learning to stratify patients according to whether they can have surgery at an ambulatory surgical center vs a hospital-based outpatient department.
Cadherin‐11 increases tumor cell proliferation and metastatic potential via Wnt pathway activation
Authors: Liu Yayu , Lei Pedro , Samuel Ronel Z. , Kashyap Anagha M. , Groth Theodore , Bshara Wiam , Neelamegham Sriram , Andreadis Stelios T.
Published: August 2023

During epithelial–mesenchymal transition (EMT) in cancer progression, tumor cells switch cadherin profile from E‐cadherin to cadherin‐11 (CDH11), which is accompanied by increased invasiveness and metastatic activity. However, the mechanism through which CDH11 may affect tumor growth and metastasis remains elusive. Here, we report that CDH11 was highly expressed in multiple human tumors and was localized on the membrane, in the cytoplasm and, surprisingly, also in the nucleus. Interestingly, β‐catenin remained bound to carboxy‐terminal fragments (CTFs) of CDH11, the products of CDH11 cleavage, and co‐localized with CTFs in the nucleus in the majority of breast cancer samples. Binding of β‐catenin to CTFs preserved β‐catenin activity, whereas inhibiting CDH11 cleavage led to β‐catenin phosphorylation and diminished Wnt signaling, similar to CDH11 knockout. Our data elucidate a previously unknown role of CDH11, which serves to stabilize β‐catenin in the cytoplasm and facilitates its translocation to the nucleus, resulting in activation of Wnt signaling, with subsequent increased proliferation, migration and invasion potential.