bluuebunny/crossref_metadata_2025 huggingface dataset:
Project-Based Learning: implementação no primeiro ano de um curso de Engenharia
Authors: Moreira José Francisco Pereira , Lima Rui Manuel Sá Pereira , Carvalho José Dinis Araújo , Sousa Rui Manuel Alves Silva , Mesquita Diana Isabel Araújo , van Hattum-Janssen Natascha
Published: November 2021

As instituições de ensino superior estão cada vez mais preocupadas com a necessidade de implementar práticas de ensino e de aprendizagem centradas no estudante. Os métodos tradicionais de ensino, baseados exclusivamente em aulas expositivas, têm se revelado pouco eficazes para promover o desenvolvimento e formação global dos nossos estudantes. As crescentes exigências do mercado de trabalho, que procuram um perfil profissional não só baseado em competências técnicas de uma determinada área de conhecimento, mas antes uma variedade de competências transversais, como o trabalho em equipa, a resolução de problemas, a responsabilidade, gestão do tempo, criatividade, inovação, resiliência, etc. exigem que as universidades se aproximem da realidade e prática profissional dos futuros graduados, criando oportunidades para a cooperação e desenvolvimento de projetos interdisciplinares. Adicionalmente, a estrutura tradicional de organização em disciplinas que as isola em si mesmo e que não permitem ao aluno ter uma visão sistémica dos problemas, visão esta tão necessária no contexto profissional, requer mudanças ou abordagens que obriguem o aluno a ter esta visão sistémica e holística. Este livro apresenta a metodologia de Project-based Learning (PBL) ou Aprendizagem baseada em Projeto, desde a sua fase de preparação até à sua implementação num curso de Engenharia. Nesse sentido, visa constituir-se como um recurso de apoio a todos os interessados em implementar PBL, nos seus contextos de ensino e de aprendizagem. Apresenta uma descrição detalhada das etapas e procedimentos necessários para a preparação, definição, arranque, execução e finalização do processo PBL, partindo da realidade de um contexto concreto, nomeadamente, o curso de Mestrado Integrado em Engenharia e Gestão Industrial (MIEGI), da Escola de Engenharia da Universidade do Minho, Portugal.
The impact of students’ generating and answering questions on their performance
Authors:   Instructional Technology Department, College of Education, King Saud University, Riyadh, Saudi Arabia, Alshalan Anas Mohammed
Published: November 2021

The aim of the research is to measure the effect of students' use of the strategy of writing questions and answering them on their achievement performance. The researcher used the achievement test to measure the differences between variables, and checked the research tool from validity-consistency-experimental application. But for the implementation of the research experiment, the students were divided into three groups, namely: The experimental group 1 (generating questions and answering them by the learners in groups), the experimental group 2 (forming and answering the questions of the learners individually), and the control group (forming questions by the teacher). In addition, the researcher used the mean and standard deviation to answer the research question and compare student performance in all three research groups. The results showed that there were significant differences between the averages of the research groups, as the experimental group 2 achieved a higher average (26,474) than the experimental group 1 (24,333) and the control group (24,857).
COVID-19 Vaccine–Related Attitudes and Beliefs in Canada: National Cross-sectional Survey and Cluster Analysis
Authors: Benham Jamie L , Atabati Omid , Oxoby Robert J , Mourali Mehdi , Shaffer Blake , Sheikh Hasan , Boucher Jean-Christophe , Constantinescu Cora , Parsons Leigh Jeanna , Ivers Noah M , Ratzan Scott C , Fullerton Madison M , Tang Theresa , Manns Braden J , Marshall Deborah A , Hu Jia , Lang Raynell
Published: November 2021

Background

There are concerns that vaccine hesitancy may impede COVID-19 vaccine rollout and prevent the achievement of herd immunity. Vaccine hesitancy is a delay in acceptance or refusal of vaccines despite their availability.

Objective

We aimed to identify which people are more and less likely to take a COVID-19 vaccine and factors associated with vaccine hesitancy to inform public health messaging.

Methods

A Canadian cross-sectional survey was conducted in Canada in October and November 2020, prior to the regulatory approval of the COVID-19 vaccines. Vaccine hesitancy was measured by respondents answering the question “what would you do if a COVID-19 vaccine were available to you?” Negative binomial regression was used to identify the factors associated with vaccine hesitancy. Cluster analysis was performed to identify distinct clusters based on intention to take a COVID-19 vaccine, beliefs about COVID-19 and COVID-19 vaccines, and adherence to nonpharmaceutical interventions.

Results

Of 4498 participants, 2876 (63.9%) reported COVID-19 vaccine hesitancy. Vaccine hesitancy was significantly associated with (1) younger age (18-39 years), (2) lower education, and (3) non-Liberal political leaning. Participants that reported vaccine hesitancy were less likely to believe that a COVID-19 vaccine would end the pandemic or that the benefits of a COVID-19 vaccine outweighed the risks. Individuals with vaccine hesitancy had higher prevalence of being concerned about vaccine side effects, lower prevalence of being influenced by peers or health care professionals, and lower prevalence of trust in government institutions.

Conclusions

These findings can be used to inform targeted public health messaging to combat vaccine hesitancy as COVID-19 vaccine administration continues. Messaging related to preventing COVID among friends and family, highlighting the benefits, emphasizing safety and efficacy of COVID-19 vaccination, and ensuring that health care workers are knowledgeable and supported in their vaccination counselling may be effective for vaccine-hesitant populations.
The Role of Physicians in Digitalizing Health Care Provision: Web-Based Survey Study (Preprint)
Authors: Burmann Anja , Tischler Max , Faßbach Mira , Schneitler Sophie , Meister Sven
Published: November 2021

BACKGROUND

Digitalization affects all areas of society, including the health care sector. However, the digitalization of health care provision is progressing slowly compared to other sectors. In the professional and political literature, physicians are partially portrayed as digitalization sceptics. Thus, the role of physicians in this process requires further investigation. The theory of “digital natives” suggests a lower hurdle for younger generations to engage with digital technologies.

OBJECTIVE

The objective of this study was to investigate the role of physicians in the process of digitalizing health care provision in Germany and to assess the age factor.

METHODS

We conducted a large-scale study to assess the role of this professional group in the progress of the digital transformation of the German health care sector. Therefore, in an anonymous online survey, we inquired about the current digital penetration of the personal working environment, expectations, attitude toward, and concerns regarding digitalization. Based on these data, we studied associations with the nominal variable age and variations across 2 age groups.

RESULTS

The 1274 participants included in the study generally showed a high affinity towards digitalization with a mean of 3.88 on a 5-point Likert scale; 723 respondents (56.75%) stated they personally use mobile apps in their everyday working life, with a weak tendency to be associated with the respondents’ age (η=0.26). Participants saw the most noticeable existing benefits through digitalization in data quality and readability (882/1274, 69.23%) and the least in patient engagement (213/1274, 16.72%). Medical practitioners preponderantly expect further improvements through increased digitalization across almost all queried areas but the most in access to medical knowledge (1136/1274, 89.17%), treatment of orphan diseases (1016/1274, 79.75%), and medical research (1023/1274, 80.30%).

CONCLUSIONS

Respondents defined their role in the digitalization of health care provision as ambivalent: “scrutinizing” on the one hand but “active” and “open” on the other. A gap between willingness to participate and digital sovereignty was indicated. Thus, education on digitalization as a means to support health care provision should not only be included in the course of study but also in the continuing process of further and advanced training.
Digital Inclusion as a Foundation for Health Equity. Comment on “Expanding Video Consultation Services at Pace and Scale in Scotland During the COVID-19 Pandemic: National Mixed Methods Case Study” (Preprint)
Authors: Weatherburn Christopher
Published: November 2021

UNSTRUCTURED

N/A
Correction: Reducing Intrusive Memories of Childhood Trauma Using a Visuospatial Intervention: Case Study in Iceland (Preprint)
Authors: Thorarinsdottir Kristjana , Holmes Emily A , Hardarson Johann , Hedinsdottir Unnur , Kanstrup Marie , Singh Laura , Hauksdottir Arna , Halldorsdottir Thorhildur , Gudmundsdottir Berglind , Valdimarsdottir Unnur , Thordardottir Edda Bjork , Gamble Beau , Bjornsson Andri
Published: November 2021

UNSTRUCTURED

REMOVE
HYDROCHEMICAL CHARACTERISTICS AND WATER QUALITY ASSESSMENT IN ABU-ZAABAL AREA, EASTERN NILE DELTA, EGYPT
Authors: EL-SHEIKH RAGAA , HEGAZY IBRAHIM , ZAGHLOOL EHAB , E. A. ALI MOHAMED , GOUDA AYMAN A.
Published: November 2021

Objective: The study presents simple tools for water resources quality classification based on its chemical compositions in Abu Zaabal area, eastern Nile Delta, Egypt and assess the water quality for different uses.
Methods: 31 water samples were collected from different water resources in the study area and analyzed for physicochemical parameters. Hydrochemical relations, contour maps and statistical methods were used to estimate the contamination indices and evaluate the water resources for different purposes.
Results: 83.3% of groundwater samples is fresh water and 16.7% are brackish water. 85.7% of surface water samples are fresh and 14.3% is saline. 92% of groundwater samples and 71.5% of surface water samples are very hard water. According to HPI values, 8% of the quaternary groundwater samples are good, 4% are poor, 4% are very poor and 84% of the samples are unsuitable. All groundwater samples and 71% of surface water samples are contaminated with respect to ammonia.
Conclusion: Higher concentrations of TDS and heavy metal may be due to the clay nature of the soil, the marine sediments in the aquifer matrix together with the dissolution and leaching of minerals from agricultural, anthropogenic and industrial activities. The groundwater in the polluted zones is considered unsuitable for human drinking.
IN-SITU FILM-FORMING SOLUTION FOR TOPICAL APPLICATION OF TERBINAFINE HCL: BIOPHARMACEUTICAL EVALUATION AND IN VIVO ANTIFUNGAL PERFORMANCE USING ANIMAL MODEL
Authors: MUSTAFFA MOHD FAIZ , RAMASAMY KALAVATHY , JAAFAR NAQIBAH , HAZIZUL HASAN MIZATON , RAMLI NOR AMLIZAN , SURATMAN SURAYA , ADAM AISHAH
Published: November 2021

Objective: The main purpose of this study is to develop a film-forming solution with optimum physical-mechanical characteristics and excellent antifungal activity to enhance deposition and penetration into the stratum corneum (SC).
Methods: The film-forming solutions of terbinafine HCl were formulated using methacrylate copolymers, polyethylene glycol 400, and ethanol as diluent. The selected formulations were subjected to test of physical-mechanical properties, drug release, drug permeation across the stratum corneum and drug deposition study. The best formulation was further evaluated for in vivo antifungal efficacy.
Results: The selected formulations exhibited superior pharmaceutical characteristics, including rapid drying, non-stickiness, and being transparency on the skin. Formulation A (FA) had significantly lower tensile strength (4.78 N/m2, p<0.05) and higher percentage elongation at break (33.61%, p<0.05), which reduced the firmness of the film, allowing it to be super-flexible in following the movement of the skin and preventing loss of film through abrasion. FA showed significantly (p<0.05) rapid drug permeation (1510.51 µg/cm2) across the stratum corneum (SC) at 24 h when compared with the other formulations and the positive control proprietary drug (PD), Terbex® cream formulation (475.8 µg/cm2).
Conclusion: Having superior physical-mechanical and drug permeation characteristics, FA can be considered as an efficient, reproducible, and efficacious antifungal formulation for topical application.
FUNCTIONALIZED POLYMERIC NANOPARTICLES: A NOVEL TARGETED APPROACH FOR ONCOLOGY CARE
Authors: RAIKAR PRASIDDHI R. , M. DANDAGI PANCHAXARI
Published: November 2021

Popular cancer therapies face extreme disadvantages, including multimedicament tolerance and non-target impact. These issues will lead to poorer patient conformity and poor levels of survival. Successful medical therapies for cancer patients are desperately required. Nano-particulate structures with a pluronic base represent revolutionary platforms for anti-cancer agent provision. These structures provide great potential for the advancement of cancer therapy due to their pharmacological properties and sufficient physicochemical characteristics. This review aims to offer a more detailed description of the pluronic drug delivery mechani sms that are currently available and explains pluronic as a medicinal polymer. Hydrophobic payload formulations and updated, targeted distribution mechanisms are explained based on pluronic formulations. This analysis offers a rundown of the current situation art related to the theranostic application of polymer micelles targeting the microenvironment of cancer cells. Some guidelines for the future scope and possible opportunities are also been addressed.
Search criteria: Primary sources such as Medline a principal component of PubMed, an online, searchable, and biomedical and life science research literature database has been used. It brings readers to almost any area of interest with research and journal articles. One of the internet resources of importance to get scientific publications is specialized scientific search engines known as Google Scholar a database of research material that can be searched for. I have used the online electronic access portal of Elsevier, such as Science Direct to its publications. Scopus is the biggest abstract and peer-reviewed literature database for scientific journals, books, and conference work. Keywords like Cancer, Pluronic, Nanoparticles, Chemotherapy, Cancer, Theranostic, Targeted, Micelles, and Core-shell are crucial as they notify search engines of the content of the site.
Range of years: 1992-2020.
LATENTIATED PRODRUG APPROACH OF DRUGS: AN OVERVIEW
Authors: P. R. DHARUN , Y. ISMAIL , PRASAD M. VIJAYA VARA
Published: November 2021

Prodrugs, with their capability of declining the adverse events and elevating the bioavailability of certain drugs, have captured enormous attention throughout the world since the 20th century. The versatility of the prodrugs that are inert and after administration releasing the parent moiety for the desired effect has become a major criterion for the scientists to incorporate this to alleviate the undesired effects of a conventional drug. About 10% of the prevailing drugs are prodrugs and their usage is being amplified owing to its critical application in cancer therapy, toxicity alleviation, and specificity. The purpose of this review is to understand the prodrugs, strategies incorporated in designing the prodrugs, applications, their crucial benefits in targeted action at a specific site of the body, their advantageous effects in chemotherapy. Also, to be acknowledged with the ongoing clinical trials and researches on prodrugs and some notable marketed prodrugs in a depth manner.
Relação anatômica entre a arquitetura interna e as zonas de segurança externas do tronco encefálico
Authors: Moraes Karina Ruiz de , Holanda Vanessa Milanesi de , Cavalheiro Sérgio
Published: November 2021

Introdução: Compreender a complexa anatomia interna do tronco encefálico permite um melhor planejamento cirúrgico ao acessar as zonas de entrada de segurança localizadas na superfície externa. Objetivo: Analisar a anatomia intrínseca do tronco encefálico através do uso de técnicas de dissecção de peças de encéfalo humano em laboratório. O objetivo é buscar a preservação de estruturas eloquentes nas abordagens cirúrgicas. Metodologia: Seis espécimes de tronco encefálico foram fixados no formol e congelados, sendo analisados por técnicas de dissecção de fibras e vistos ao microscópio para definir a anatomia (D.F. Vasconcellos M 900A). As estruturas estão apresentadas em diversos ângulos, destacando-se uma série de secções transversais axiais paralelas. Resultados: Quando as lesões não afloram à superfície pial, as zonas de entrada de segurança representam estreitos referenciais em que há paucidade de estruturas eloquentes e ausência de vasos perfurantes. Conclusão: O conhecimento anatômico é fundamental para tornar o acesso cirúrgico ao tronco encefálico mais seguro.
Dr. Albert L. Rhoton Jr: sua vida e contribuições para a Neurocirurgia
Authors: Júnior Luiz Severo Bem , Coimbra Ana Luiza Serra , Lins Camila Mendonça , Gemir Júlia Lins , Costa Lucas Nunes Viana da , Silva Millena Rayssa de Andrade , Lira Carlos Cezar Sousa de , Valença Marcelo Moraes , Filho Hildo Rocha Cirne de Azevedo
Published: November 2021

Dr. Albert L. Rhoton, conhecido como um dos pioneiros no estudo da neuroanatomia microcirúrgica, dedicou, com muito brilhantismo, parte de sua vida à elaboração de inúmeras linhas de pesquisas nesta área do conhecimento através de estudos realizados por ele e por seu laboratório ao longo dos anos, uma vez que havia, na época, uma clara necessidade de aprofundar os conhecimentos a respeito da mesma. A fim de compreender melhor seus estudos e contribuições para a especialidade neurocirúrgica, realizou-se uma pesquisa nas plataformas MedLine/PubMed e SciELO, com os descritores “Rhoton”, “Rhoton’s lab”, “education”, “historical review”, “anatomy”, “microsurgical anatomy” e “neurosurgery” combinados entre si, resultando em seis artigos que serviram de base para a elaboração da presente revisão narrativa. A partir desta, foi possível inferir que seus trabalhos versaram, principalmente, a respeito dos temas: nervos cranianos, hipófise e sela túrcica, artérias, ventrículos, conhecimentos relativos ao estudo de base de crânio e estruturas internas do cérebro, a fim de correlacioná-las com as descobertas anatômicas e as novas abordagens cirúrgicas avançadas Estas, possibilitaram grandes avanços na especialidade, inaugurando novas técnicas, sugerindo abordagens mais eficazes e seguras e trazendo descrições anatômicas de maior acurácia e riqueza de detalhes, graças às técnicas inovadoras de pesquisa e ilustração adotadas por seu laboratório, que facilitaram a aprendizagem médica. Além disso, é importante ressaltar que suas contribuições não foram restritas apenas ao seu país de atuação, tendo se disseminado ao redor do mundo, podendo-se destacar a América Latina e, dentro dela, o Brasil.
Brain cryptococcoma in immunocompetent patient. A case report
Authors: Cherain Luiz Gabriel Gonçalves , Rocha Carollayne Mendonça , Oliveira Marcos Antônio de , Pereira Denis Batista , Bárbara Pinto Michelli , Rabelo Nícollas Nunes
Published: November 2021

Cryptococcosis commonly associated with immunosuppressed individuals is an infection caused by Cryptococcus neoformans/var. gattii. This infection has high mortality worldwide. C. neoformans inhabits the lung, later spreading to the Central Nervous System (CNS) which is the most significant site in the clinical manifestation of the disease. However, the prevalence in the CNS is low in immunocompetent individuals. Case presentation: A 42-year-old woman presented only headache, nausea, vomiting and simple partial epileptic seizure. Neuroimaging showed an expansive hypointense frontal lesion and a neurosurgical treatment was proposed, confirmed by histopathological analysis. Discussion: The exposure to C. neoformans among human populations is almost ubiquitous. The immunological status of the patient, the parasitic load and the virulence of the infectious strain are fundamental for the progression of the pathology. The balance of these factors is decisive for the prognosis. Currently, treatment is limited and consists of long term antifungal therapy. Conclusion: In this case, the necessity of differential diagnosis like brain tumors (e.g.: lymphoma and glioblastoma multiforme), resulting in poor prognosis and late treatment is seen. A neurosurgical approach should be instituted as soon as possible when pharmacological treatment is ineffective.
Partial resolution of cerebrovascular stenosis after conservative treatment of moyamoya disease
Authors: Tedde Filho Gustavo , Nunes Mariana Silva , Machado Marcelle Rehem , Parente Bruno de Sousa Mendes , Waihrich Eduardo
Published: November 2021

Relatamos o caso de um paciente masculino, 28 anos de idade, sem histórico de descendência oriental, que procurou atendimento após apresentar dois quadros de hemiparesia esquerda reversível em um intervalo de seis meses. Lesões isquêmicas não foram evidenciadas nas tomografias computadorizadas (TC) de crânio. O diagnóstico de doença de moyamoya foi confirmado por meio da angiografia cerebral diagnóstica com subtração. A revascularização cirúrgica foi proposta, porém recusada pelo paciente. Iniciou-se tratamento não invasivo com mono-antiagregação plaquetária e rosuvastatina, obtendo-se regressão parcial da estenose.
Sarcoma sinovial mimetizando schwannoma em membro inferior
Authors: Silva Henzo Theodoro Fonseca , Barbosa Abraão Mota , Gonçalves Daniel Buzaglo , Santos Gabriel Pinto dos , Reis Franklin , Amorim Robson
Published: November 2021

O sarcoma sinovial (SS) é um tumor de origem mesenquimal com diferenciações epiteliais variáveis, representando 5 a 10% de todos os sarcomas de partes moles e cerca de 95% destes ocorrem nas extremidades. Acometem principalmente adultos jovens, predominantemente perto de grandes articulações, apresentando-se como uma massa palpável de crescimento lento. Relato de Caso: Paciente feminina, 35 anos, iniciou quadro de tumefação de caráter progressivo em face lateral de panturrilha esquerda, evoluindo com dor a deambulação, aumento da tumefação e da dor local. Discussão: Schwannoma e SS são tumores distintos, mas que no modo de evolução podem apresentar-se de forma semelhante, como pequena massa palpável de crescimento lento, muitas vezes dolorosa, aumentando o grau de dificuldade para o diagnóstico. Comentários: O SS pode manifestar-se com características relacionadas ao tamanho, sintomatologia, apresentação radiológica e tempo de evolução que são semelhantes na evolução de schwannomas de nervos periféricos, podendo incorrer em dificuldade diagnóstica.
Diastematomielia cervical associada a lipoma e hipotrofia de membros superiores: relato de caso e revisão da literatura
Authors: Gonçalves Daniel Buzaglo , Cabral Lucas de Cristo Rojas , Santos Maria Izabel Andrade dos , Silva Henzo Theodoro Fonseca , Oliveira Louise Makarem , Coutinho Gabriela Campos da Silva , Falcão Marcos Gabriel do Vale Gomes , Ramos Stephanie , Viana Rodrigo , Cohen Moyses , Reis Franklin , Amorim Robson
Published: November 2021

Diastematomielia é um disrafismo espinhal oculto (HSD), descrito pela primeira vez em 1837 e representa 3,8% de todos os HSD. Poucos casos de diastematomielia cervical foram relatados, uma vez que a localização principal da doença é a coluna torácica baixa, no cone medular. Neste artigo, fizemos uma revisão da literatura e descrevemos um caso raro de diastematomielia cervical associada a lipoma e hipotrofia de membros superiores. Relato do caso: Uma mulher de 48 anos apresentou-se em nosso ambulatório com queixa de atrofia da porção distal do membro superior direito, que evoluiu para o lado contralateral após seis meses. No intraoperatório, a membrana epidural foi aberta, sendo encontrada uma lesão amarelada, reforçando o diagnóstico sugestivo de lipoma. Após a remoção, a medula espinhal dividida tornou-se clara. Discussão: Segundo nossa pesquisa, este é o primeiro caso de lipoma associado a diastematomielia na região cervical. Desde 1985, apenas 23 pacientes adultos foram diagnosticados com exames de imagem e tratados cirurgicamente. É possível dividir os pacientes com malformação da medula espinhal (SCM) em dois grupos. Um grupo de pacientes diagnosticados nos primeiros anos de vida com sintomas remanescentes e outro grupo formado por aqueles diagnosticados na idade adulta. Nosso paciente encontra-se no segundo grupo.
Craniopharyngiomas: A literature review
Authors: Carapeba Rafael Peron , Gobbo Giovanni Rezende , Oliveira Eduardo , Pasquini Carolina Abrahão , Nóbrega Adriane Okunami , Santos Leandro Rezende dos , Strapasson Atahualpa Cauê Paim
Published: November 2021

Esta é uma revisão comparativa dos modelos diagnósticos e terapêuticos dos craniofaringiomas. Os craniofaringiomas são tumores raros, quase invariavelmente benignos, extra-axiais e não gliais do sistema nervoso central. Eles estão mais comumente localizados na sela túrcica e na região suprasselar. São tumores cuja apresentação clínica se baseia no efeito de massa em estruturas adjacentes, como perda de visão, distúrbios do desenvolvimento hipofisário e endocrinopatias. Este estudo foi elaborado a partir de informações coletadas nas bases de dados da Biblioteca Virtual em Saúde (VHL), PubMed e LILACS, excluindo referências duplicadas ao final da busca. Os artigos selecionados foram publicados entre 2001 e 2019. A partir da pesquisa realizada, é possível concluir que, embora os CFs (craniofaringiomas) sejam uma forma rara de tumores, eles têm sido amplamente divulgados em toda a comunidade médica com apresentações clínicas extensas e correspondentes. Esses achados são de relevância prática direta e corroboram nossa intenção de reunir informações confiáveis a respeito dessa doença.
La historia clínica en el proceso judicial por responsabilidad médica en Cuba. Alcance y valor probatorio
Authors: Momblanc Liuver Camilo
Published: November 2021

El presente texto persigue como propósito principal analizar el alcance y valor probatorio de la historia clínica en el ámbito jurídico-procesal a la luz del ordenamiento jurídico cubano frente a la discutida definición de su carácter de documento público o privado. Como objetivo secundario, se pretende enunciar aquellos factores que constituyen riesgos legales asociados a la historia clínica e inciden en su valor probatorio. Con tales designios, la metodología seguida estuvo sustentada esencialmente en los métodos analítico-sintético, inductivo-deductivo y el hermenéutico, aplicados en el marco de una indagación de tipo documental, argumentativa y exploratoria. Entre los resultados se muestra el comportamiento del estado del arte del tema en el país y las falencias legales en este aspecto. La conclusión señala la necesidad de armonizar la legislación de salud, que se refiere a la historia clínica, con las exigencias establecidas desde nuestra norma procesal civil en cuanto al carácter público o privado de los documentos.
La reforma laboral y sus fundamentos económicos en perspectiva histórica
Authors: Harari Ianina , Bil Damián
Published: November 2021

Este trabajo se propone analizar los fundamentos económicos que motivaron la presentación de un nuevo proyecto de reforma laboral durante el gobierno de Mauricio Macri en Argentina. Para ello adoptaremos una perspectiva histórica mediante la reconstrucción de las transformaciones que ha sufrido la legislación laboral, específicamente la ley de contrato de trabajo, que es la que rige la casi totalidad de los acuerdos laborales. También abordamos la evolución de las relaciones laborales en las últimas décadas y los intentos por parte del empresariado argentino de conseguir condiciones más favorables para un uso flexible de la fuerza de trabajo. Nuestro análisis muestra que la reforma laboral es parte de una estrategia de mediano plazo cuyo objetivo es mejorar las condiciones de acumulación de capital en Argentina, incluyendo un aumento de la explotación de la fuerza de trabajo. La metodología utilizada no solo se basará en el análisis cualitativo de las fuentes legislativas, sino también en análisis cuantitativos de información estadística nacional y mundial. Nos remitimos a diversos tipos de fuentes: legislación laboral, convenios y acuerdos de diferentes períodos históricos, series estadísticas oficiales nacionales e internacionales y aportes de otros autores.
Transformation of the acute myeloid leukemia to acute B cell lymphoblastic leukemia with CAR-T cell therapy: a case report and review of the literature
Authors: Zhang Yanan , Liu Fengan , Wang Xue , Cao Jiang , Chen Wei , Qi Kunming , Xu Kailin , Cheng Hai
Published: November 2021

Lineage conversion is used to describe acute myeloid or lymphoid
leukemia becomes the opposite at relapse.We report a 4-year-old child
with acute myeloid leukemia who was converted to acute lymphoblastic
leukemia at relapse and received chimeric antigen receptor T (cell)
therapy for reference.
Seychelles warblers with silver spoons: juvenile condition is a lifelong predictor of annual survival, but not annual reproduction or senescence
Authors: Brown Thomas , Dugdale Hannah , Hammers Martijn , Komdeur Jan , Richardson David
Published: November 2021

1) The environment experienced during development, and its impact on
intrinsic condition, can have lasting outcomes for adult phenotypes and
could contribute to the individual variation in senescence trajectories.
2) However, the nature of this relationship in wild populations remains
uncertain, owing to the difficulties in summarizing environmental
complexity and long-term monitoring of individuals from free-roaming
long-lived species. 3) In this study, we determine whether juvenile
condition (derived from measures of body mass and size) is associated
with senescence-related traits of a closely monitored population of
Seychelles warblers (Acrocephalus sechellensis). 4) Juveniles with a
higher condition index were more likely to survive to adulthood –
suggesting these juveniles experienced better developmental conditions.
Furthermore, these juveniles as adults were in better condition and had
higher rates of annual survival, independently of age. In contrast,
there was no association between juvenile condition and declines in
adult telomere length (a measure of somatic stress) nor annual
reproduction. 5) These results indicate that juvenile condition, while
not associated with senescence trajectories, can influence the
likelihood of surviving to old age due to silver-spoon effects. This
study shows that measures of intrinsic condition in juveniles can
provide important insights into long-term fitness of individuals in wild
populations.
Forhandling om tekst og kontekst. En studie av 7. trinns-elevers meningsforhandling i intendert utforskende gruppesamtaler
Authors: Kvistad Tone Holten , Kjelaas Irmelin , Matre Synnøve
Published: November 2021

Denne artikkelen undersøker hvordan et utvalg elever forhandler om mening i gruppesamtaler i norskfaget. Materialet er hentet fra en kasusstudie i en klasse der det ble gjennomført et ti-ukers undervisningsforløp med mål om å fremme elevenes samtaleferdigheter og spesifikt samtaleformen utforskende samtale (eng. exploratory talk) (Mercer & Littleton, 2007). Med et sosiokulturelt og dialogisk rammeverk, og bruk av begrepene samtaleramme (Goffman, 1974) og kontekstualiseringssignaler (Gumperz, 1982), analyseres tekstsamtaler i tre grupper mot slutten av undervisningsforløpet. Vi finner at elevene orienterer seg mot ulike samtalerammer og tar i bruk ulike interaksjonelle og innholdsmessige ressurser, slik at utforskingen blir mer sammensatt, kreativ og lekpreget enn det som ofte beskrives i teori og empiri om utforskende samtale (jf. f.eks. Mercer et al., 2019). Artikkelens formål er å belyse elevenes mangfoldige meningsforhandling, samt å diskutere ulike forståelser av hva utforskende samtale er og kan være i samtaler mellom elever.
English abstract
Negotiation about text and context. A study of students’ peer interaction in intended exploratory group talk
This article examines how a sample of seventh-grade students (12–13 years) negotiate meaning in peer group talk in Norwegian L1 lessons. The data is collected from a single case study in one classroom, where ten lessons were conducted to promote talk skills, specifically exploratory talk (Mercer & Littleton, 2007). With a sociocultural and dialogical framework, and the concepts of frame (Goffman, 1974) and contextualisation cues (Gumperz, 1982), we analyze text discussions in three peer groups from the end of the intervention. We find that the students orient themselves towards different talk frames and use different interactional resources and knowledge references, so that their ways to shared understanding become more complex, creative, and playful than what is often described in theory and empirical data on exploratory talk (cf. Mercer et al., 2019). The purpose of the article is to shed light on the complexity of students’ meaning negotiation, as well as to discuss different notions of what exploratory talk may entail in peer groups.
The Role of Tat Twam Asi Teachings in Leader Member - Exchange Mediated by Teamwork towards BUMDes Employee Performance In Buleleng Regency
Authors: Sudarnaya Ketut
Published: November 2021

The Law Number 6 of 2014 concerning Villages, gives enthusiasm for villages to initiate themselves by creating the spirit of “Building Village” then BUMDes is born as an independent business institution for rural communities and will be able to develop its potential, if BUMDes pays close attention to the performance of employees is one of the factors that play an important role in achieving organizational goals. The purpose of this study is to explain the effect of leader member-exchange (LMX) and teamwork as a mediating variable on employee performance, both direct and indirect effects. The results showed that leader member-exchange (LMX) has a positive and significant effect on employee performance, teamwork has a positive and significant effect on employee performance and teamwork is a partial mediator of the influence of leader member-exchange (LMX) on the performance of BUMDes employees in Buleleng Regency. This research can provide knowledge and understanding for stakeholders in implicating teamwork in the relationship between leaders and subordinates (LMX) in improving employee performance.
Development of Resilient Measurement Instruments for High School Students in Denpasar
Authors: Olok Wilhelmina , Dantes Nyoman , Suarni Ni Ketut
Published: November 2021

The purpose of this development research is to determine the value of the validity and reliability of the tough character instrument. This study was designed with research and development methods. Analysis of the data used in the CVR and CVI tests from Lawshe, the empirical test with the product moment formula, while to test the reliability using Cronbach's alpha. The instrument validation test was carried out by experts. The results of data analysis using the Lawshe CVR test obtained an item value (CVR> 0), then the CVI value was obtained at 0.96, this value means that the content validity index of 45 items in the tough character instrument is very good. The results of the calculation of the validity of the item validity test using the Product Moment formula according to the valid category criteria. this shows that the level of reliability of the tough character instrument is very high, so this tough character instrument product is very important to be developed for students in high school.
Development of Group Counseling with Modeling Techniques to Increase Efficiency in Career Decisions of Students
Authors: Mutmainah Siti , Gading I Ketut , Dharsana I Ketut
Published: November 2021

This study aims to develop a guidebook for group counseling on modeling techniques to improve self-efficacy in career decision making for vocational students. This research is a type of research and development (R&D). The product acceptance tester of this manual involves 5 experts and practitioners of guidance and counseling. Testing the validity of the content of the manual product using the Lawshe formula and testing the effectiveness by finding the effective contribution (nn effect size) using the Cohen-D formula. The results of the acceptance test data analysis with the Lawshe CVR test obtained a value per item (CVR> 0 or 1) for all items, then the results of the Lawshe CVI analysis obtained a score of 1, then this result means that the value of the content validity of the product content of the group counseling guidebook Modeling technique is high, calculate the effectiveness of the guidebook and get the results 3.17 So based on the value of the effectiveness of the above then according to the criteria. If the value of effect size > 0.50 then the group counseling guide modeling technique is effective to minimize self-efficacy students'in making career decisions. This shows that the level of effectiveness of the modeling technique group counseling guidebook for SMK students is very good, so it is important to develop it for students in school.
Development of Self-Change Classical Guidance Module to Reduce Student’s Stress Due to COVID-19
Authors: Wahyudi Hendro , Dharsana I Ketut , Suranata Kadek
Published: November 2021

The COVID-19 pandemic is affecting to the learning process in school. As an effort to reduce the spread of virus, all of learning activity now conducted via online. Various obstacles arise during the online learning. This new condition increase the level of student’s stress and requires students ready to make self-change. This study is research and development that aims to develop and evaluate the classical guidance module as an instrument to help students make self-change in order to reduce their stress. The development procedure conducted by following 4D model (Thiagarajan, 1974). Five expert involved as judges to evaluate the content validity of module and 30 students were involved as subject on piloting study. Results of expert judgement were analyzed using formula Lawshe and show the module has a “very special” content validity index ( CVI = 1). Results of piloting study show the module has “very good” category in all aspect of evaluation. Based on the results, it show that the classical guidance module developed in this study feasible to use as an instrument to help students make self-change in order to reduce their stress levels due to COVID-19.
Development of Consistency Personality Measurement Instruments on Students at SMA Dwijendra Bualu
Authors: Purnama Sari Ni Komang Shintia Agustini , Suarni Ni Ketut , Dantes Nyoman
Published: November 2021

This research is a type of research and development. Measurement of personality consistency was carried out by testing the validity of the instrument items by applying the product moment correlation formula and testing the reliability of the questionnaire with Cronbach's Alpha coefficient. Based on the VC calculation on the content validation test with the Gregory formula, the results are 1 or > 0, it is stated that the personality consistency character instrument is very valid. The results of data analysis conducted to determine the validity of items using the product moment formula obtained 39 items declared valid or very good. Based on these results, it is expected that students are able to develop personality consistency so that they have goals and efforts or continuous development, this is still needed even though they have succeeded in achieving their goals in life.
Kecerdasan Emosional dengan Organizational Citizenship Behavior (OCB) pada Karyawan UMKM Nabil Konveksi Tingkir
Authors: Setiyawan Setiyawan
Published: November 2021

This study aims to determine the relationship between Emotional Intelligence and Organizational Citizenship Behavior (OCB) among MSME employees Nabil Conveksi Tingkir. Participants are employees of MSME Nabil Conveksi Tingkir with a total of 40 people. Data collection uses the Emotional Intelligence Scale which consists of 30 items and the Organizational Citizenship Behavior Scale which consists of 30 items, both of which have met good reliability requirements. Data analysis used Pearson's product moment correlation technique. The results of this study indicate a correlation coefficient of 0.909 with a significance value of 0.00 (p <0.05), which means that there is a significant positive relationship between Emotional Intelligence and Organizational Citizenship Behavior (OCB) in MSME employees Nabil Conveksi Tingkir. Through this research, it is hoped that it can help companies in an effort to improve employee performance, one of which is by maintaining and improving the employees' physical and non-physical work environment.
Pelaksanaan Kode Etik Konselor Dalam Hubungan Ganda Di Sekolah
Authors: Abdillah Nurfauzy , Kurniawati Siti Zahra , Marjo Happy Karlina
Published: November 2021

Abstract: Multiple relationships or multiple roles are relationships that occur professionally and non-professionally. This study aims to explore the experiences of school counselors regarding multiple relationships in counseling with students. This study uses a qualitative research method with a case study design. The sampling technique used was non-probability sampling with a purposive sampling form. The subjects in this study were 2 Guidance and Counseling teachers. Data collection was carried out by interview. The results showed 1) The implementation of counseling in schools in managing multiple relationships by determining boundaries and explaining the different roles to students in the counseling process to minimize the risk of multiple relationships. 2) School counselors in building social relationships, need to avoid special closeness with students as a form of maintaining the counselor's professional identity 3) Ethical violations of multiple relationships in schools such as providing understanding to students as well as providing punishment and a dual role between counseling teachers and subject teachers.Indonesian Abstract: Hubungan ganda atau peran ganda merupakan hubungan yang terjadi secara professional dan non-profesional. Penelitian ini bertujuan untuk mengeksplorasi pengalaman konselor sekolah tentang hubungan ganda dalam konseling dengan siswa. Penelitian ini menggunakan metode penelitian kualitatif dengan desain studi kasus. Teknik sampling yang digunakan adalah non-probability sampling dengan bentuk purposive sampling. Subyek dalam penelitian ini 2 orang guru Bimbingan dan Konseling. Pengumpulan data dilakukan dengan wawancara. Hasil penelitian menunjukan 1) Pelaksanaan konseling di sekolah dalam mengelola hubungan ganda dengan  menentukan batasan dan menjelaskan tentang perbedaan peran kepada siswa dalam proses konseling untuk meminimalisir resiko dari hubungan ganda. 2) Konselor sekolah dalam membangun hubungan sosial, perlu menghindari kedekatan khusus dengan siswa sebagai bentuk menjaga identitas professional konselor 3) Pelanggaran etis hubungan ganda di  sekolah seperti memberikan pemahaman kepada siswa sekaligus memberikan hukuman dan adanya peran ganda antara guru konseling dan guru mata pelajaran
OPTIMALISASI PENGELOLAAN GERBANG TOL KALIANDA PROVINSI LAMPUNG
Authors: Anggraini Melisa , Sulistyorini Rahayu , Zakaria Ahmad
Published: November 2021

Jalan tol merupakan jalan bebas hambatan bagi kendaraan bersumbu dua atau lebih yang penggunanya wajib membayar tarif tol dan bertujuan untuk mempersingkat jarak dan waktu tempuh. Oleh sebab itu tujuan dalam penelitian ini adalah mengetahui kinerja pelayanan gardu tol pada gerbang tol Kalianda dan mengetahui jumlah gardu tol optimal sesuai dengan tingkat kedatangan kendaraaan. Penelitian ini dilakukan di gerbang pintu tol Kalianda Provinsi Lampung dengan data yang digunakan adalah jumlah gardu tol saat ini, data kedatangan kendaraan pada gardu standar pelayanan minimal, sarana dan prasarana dan lalu lintas harian. Hasil penelitian diperoleh: (1) Kinerja pelayanan gardu tol Kalianda Provinsi Lampung untuk saat ini untuk tahun 2019 masih cukup optimal untuk digunakan dikarenakan masih mampu untuk memberikan pelayanan secara cepat sehingga tidak menimbulkan antrian yang cukup panjang dan berakibat kemacetan, namun untuk tahun 2029 atau 10 tahun mendatang gardu tol Kalianda untuk waktu pelayanan 2 sampai dengan 8 detik masih cukup optimal melayani kendaraan yang datang namun untuk waktu pelayana 9 sampai dengan 14 detik membutuhkan perencanaan ulang dikarenakan gardu tol Kalianda sudah tidak mampu lagi memberikan pelayanan secara maksimal kepada 804 kendaraan. (2) Jumlah gardu tol optimal sesuai dengan tingkat kedatangan kendaraaan yang ada di gerbang tol Kalianda.
Study of Testing on Transformers and its Significance
Authors: Patel Ramesh Kumar , Upadhyay Madhu
Published: November 2021

Transformers make up the main electrical network of the equipment. Failure of a transformer leads to loss of income and affects the reliability of the power supply for consumers. In order to ensure long and trouble-free operation of the transformers, various diagnostic tests are performed and corrective actions are initiated throughout their lifetime. There are many methods to access the residual life of transformers, for example short circuit tests on transformers and areas of application.
Performing Archives: Documentary Theatre, Transition and Adaptation to a New Lifestyle in Romanian Society
Authors: Felseghi Alexandra
Published: November 2021

"The change of political regimes and the long period of transition that followed afterwards brought dramatic, even tragic shifts in common people’s lives, who were born and raised in the Eastern Bloc. These experiences, which were strikingly common in Eastern European countries, have left significant marks in nowadays society, which historians and artists alike are trying to analyze and explain to their audiences, in a personal and accessible form.
This article aims to analyze the manners in which recent history themes, like the period of transition, economy and the essential lifestyle changes which came as a consequence, are researched and handled in Romanian documentary theatre. As follows, two theatre productions of this kind will be presented. They were considered to be a real success in the independent theatre scene in the past five years and their specificity is the shared socio-political context between stage and audience.

Keywords: documentary theatre, archives, transition, recent history, non-Aristotelian theatre, independent theatre, consumerism, society.
"
Direct and Indirect Evaporative Cooling Strategies: An Analysis
Authors:   Assistant Professor, Department of Mechanical Engineering, Acropolis Institute of Technology and Research, Indore, Madhya Pradesh, India, Mishra Sakshi
Published: November 2021

Evaporative cooling can be understood as natural response of human body to effective climate control. It is the similar to the cooling principle that human body practices when moisture/ sweat vaporizes and cools off the skin. Needing less energy input, evaporative cooling is perfectly fit for uses in which decreasing high temperatures as well as energy consumption is the requisite. Evaporative cooling is an energy competent resolution for trades, where hot inside environments lead to low output, productivity and discontented employed workers. This could also upsurge the amount of faults and mishaps in the production lines. There are many technologies in place used in poultry, horticulture, swine and dairy industries such as in-duct direct evaporative cooling, exhaust air evaporative cooling, in-direct evaporative cooling and direct air evaporative cooling. In this paper, different evaporative cooling technologies have been discussed.