bluuebunny/crossref_metadata_2025 huggingface dataset:
Collaborative Futures: Arts Funding and Speculative Fictions
Authors: Schnepf J. D.
Published: January 2021

According to scholars of literary sociology, US arts institutions—from the federal government to the writers’ colony to the creative writing program—have been central to the shaping of US literature for the better part of a century. This paper offers a preliminary investigation of the global crowdfunding platform Kickstarter as an emerging arts institution. Drawing on Kim Stanley Robinson and Marina Abramović’s artistic collaboration as a case study, the paper argues that the appearance of the Marina Abramović Institute (MAI) in Robinson’s novel New York 2140 troubles the author’s stated generic commitments to “realist speculative fiction”—fiction that bases its vision of the future on the state of things in our present. In addition to furnishing uncertain conditions of production for the novel, Kickstarter’s funding model solicits short-form speculative fiction organized around neoliberal selfhood from its artists. With the assistance of Kickstarter’s networked platform, the MAI’s capital campaign reimagined private funding as public performance art, as dutiful civic engagement, and as reward for artists willing to narrate entrepreneurial optimism.
INCIDENCE OF CONFIRMED MANIFEST VIRAL INFECTION IN CASES OF ISCHEMIC STROKE, DEPENDING ON THE SEASON
Authors: Turchina N.S. , Cherenko T.M. , Trepet L.N. , Rybalko S.L. , Starosyla D.B.
Published: January 2021

Relevance. Seasonal differences in stroke incidence are associated with various physical factors, some associated with pathophysiological changes in the body leading to ischemic stroke. At the same time, there is little research into the differences in the frequency of detection of the genome of herpes virus infection and influenza virus, depending on the season.

Objective.  Investigate the existence of associations between the season and the frequency of virologically confirmed herpezoid infection manifested by herpezoid virus and influenza virus of patients with ischemic stroke.

Materials and methods. In the period from 01.01.2017 to 31.12.2017. during the year at the bases of the neurological and department of the Alexandrovsky Clinical Hospital Centre. Kyiv conducted a study of 144 cases of cerebral ischemic stroke with the medium-severe neurological deficit: 78 (54.2%) women and 66 (45.8%) men, with an average age of 63.1 0.8 years. Neurological examination and identification of the genome of herpes viruses and influenza virus, performed with the help of a polymerase chain reaction (PCR), was carried out monthly in 12 patients hospitalized by ambulance. The account was taken of the presence of a viral manifestation if it preceded the stroke within 2 weeks.

Results. 36 cases were examined each season. The ratio of men to women was 45.8 / 54.2 in total and did not differ between seasons, p = 0.514. 32 (22.2 percent) patients have demonstrated a viral infection. In winter, 11 (34.4 percent), in spring, 7 (21.9 percent), in summer, 4 (12.5 percent), in autumn, 10 (31.3 percent), and all p. At the same time, during the summer period, the incidence of viral manifestation was definitely lower than in winter, p = 0.042. Virus genomes were found in 12 (33.3 percent) patients in winter, 7 (19.4 percent) in spring, 5 (13.9 percent) in summer, 12 (33.3 percent) in autumn and p = 0.131 rice. During the summer period, the frequency of PCR-confirmed herpes virus infection was definitely lower than in the winter-autumn season, p = 0.033.

Conclusions. Viral manifestations of herpes and influenza virus in the blood are more frequent during the winter and autumn periods; the frequency of detection indicated viral infection from October to January is reliably higher than the rate from March to August inclusive.

In 25.0 percent of patients with ischemic stroke, the genome of herpes viruses and influenza virus in the blood is detected. In the event of a demonstration, the frequency of the above-mentioned viral infection is clearly higher (90.6 percent as against 9.4 percent) than that of patients without it.
Asia Minor Refugee Associations in Lesvos (1914-1936)
Authors: Pelteki Afroditi
Published: January 2021

This paper focuses on the formation and dynamic of the Asia Minor refugee association in Lesvos island (in Greece), during two historical periods: the period known as the First Persecution (Protos Diogmos, in Greek) (1914-1918) and the interwar period (1922-1936). Collectivities of first refugee generation are transformed into communities, unions and associations at the host country (Lesvos), trying to integrate into society and constitute their social reality, structuring new collective identities, collective memories and historical conscience. The present case study relies on primary sources and archival material. It provides us the possibility of both comparative study and exploration/analysis of Asia Minor’s refugee association development, since it constitutes part of an ongoing research regarding the Asia Minor Refugee Memory, resulting through genealogical succession within the Asia Minor’s Refugee Associations institutional context, in Lesvos.
Modeling the Effect of Family Atmosphere, School Atmosphere, and Social Support on Aggressiveness and Addiction Preparedness Among Students: The Mediating Role of Extroversion
Authors:   Department of Psychology, Faculty of Psychology and Social Sciences, Central Tehran Branch, Islamic Azad University, Tehran, Iran., Shahriari Shaghaghi Zohre , Ghanbaripanah Afsaneh ,   Department of Psychology, Faculty of Psychology and Social Sciences, Central Tehran Branch, Islamic Azad University, Tehran, Iran., Tajalli Parisa ,   Department of Psychology, Faculty of Psychology and Social Sciences, Central Tehran Branch, Islamic Azad University, Tehran, Iran.
Published: January 2021

Background: The increased rates of aggression and drug abuse among students are considered an important health issue. Therefore, the present study aimed to investigate the relationship between the emotional atmosphere of the family, the school climate, perceived social support, aggressive behavior, and preparedness for addiction among students, considering the mediating role of extroversion. Methods: This research used the analytical-correlative method. Also, the statistical population included all high school students in Tehran, during the academic year of 2017-2018. Results: The school environment had a significant direct effect on the preparedness for addiction. Besides, we identified the indirect effect of the school environment on irregular drug addiction. The hypothesized model showed the full effect and the nonsignificant direct effect of perceived social support on aggressive behavior. Moreover, there was a significant indirect effect between perceived social support and aggressive behavior. However, there was no direct or indirect effect between perceived social support and preparedness for addiction and the existence of extroversion’s mediating function. Conclusion: Thus, teachers and school administrators are recommended to discuss the psychological environment of the family, the school atmosphere, and perceived social support.
The Application of Providing Analysis Based on Durian Seeds to Improve Protein Intake and Hemoglobin Levels of School Children
Authors: Oppusunggu Riris
Published: January 2021

School-age children are at high risk of anaemia, because of their low haemoglobin levels due to lack of iron intake. Anaemia causes pain and death, inhibits brain development, motor, mental, intelligence and physical growth, decreased physical abilities, pale faces which will reduce enthusiasm and learning achievement of school children. The purpose of this study was to determine the effect of giving lemuru fish sausage made from durian seeds on protein intake and haemoglobin levels in children with anaemia. This type of research is a quasi-experimental, namely the pre-test design and post-test experiment. Lemuru fish sausage made from durian seeds was given every day for 30 days to 30 school-age children in SD Negeri Jati Sari Lubuk pakam City, Deli Serdang Residence. Measurement of Haemoglobin and food consumption (energy, protein, vitamin C and iron) was carried out before and after the intervention. The results showed that most of the intake of energy, vitamin C and iron in school children was in the <100% category. The mean Haemoglobin before the intervention was 10.9 g / dl; after the intervention, the mean Haemoglobin was 12.1 g / dl. The mean increase in hemoglobin 1.2 g / dl was statistically significant (p-value = 0.000). It has been recommended to increase the time to intervene and use iron status indicators in other studies.
Increased Productivity of Oyster Mushroom Chips Through Business Management, Finance, and Handling Post-Harvest Management
Authors: Desi Ika
Published: January 2021

The community subjection activities is a partnership program between the Community Partnership Program (PKM) with Dolok Masihul (Domas) Farmer Group partners. The problems are (1) Production aspects include a) Oyster mushroom chips are oily and less crunchy and do not last long; b) Plastics and labels used are still inadequate and straightforward because they are not accompanied by product information as well as packaging for oyster mushroom chips which is even done manually. (2) Aspects of Business and Financial Management, among others: a) Marketing is still carried out conventionally. b) Business management is always simple, carried out in a family manner, and there is no product legality. c) There is no separation between household finances and business finances. d) There are no records or business bookkeeping so that it is difficult to calculate the profits it gets. This community service aims to increase the knowledge, skills, and income of the Domas Farmer Group and the surrounding community through training in production, finance, and marketing. Community service activities are carried out using method 1). Transfer of knowledge, such as lectures and discussions, 2). Training, and 3). Bookkeeping assistance for the Oyster Mushroom Chips business. The results to improve the skills and knowledge of the Domas farmer group include making Oyster Mushroom chips using Deep Fryers and Spinners, knowing the use of social Media for marketing, and being able to make a financial report—publishing the Compilation Guide Book.
Eco enzyme and its benefits for organic rice production and disinfectant
Authors: Hasanah Yaya
Published: January 2021

Eco enzyme is a fermented liquid from organic waste fruits, vegetables, and other organic waste which is very useful for agriculture, health, and households. One of Deli Serdang villages that are very vulnerable to Covid-19 is Karang Anyar Village, located in Beringin District, only about 5 km from Kuala Namu International Airport. On the other hand, in Karang Anyar Village, there is a Mekar Pasar Kawat farmer group that cultivates organic rice that needs liquid organic fertilizer (LOF). This community service aims to educate the public about using an eco enzyme from household waste as liquid organic fertilizer (LOF) and disinfectant. Implementing community service that is carried out is training and practice of making eco enzyme and its benefits, direct practice of demonstration plot of rice cultivation by utilizing eco enzyme as LOF. The results are training and mentoring in making eco enzyme based on household waste, training and hands-on practice on applying eco enzyme in the environment as disinfectant, training, and direct demonstration plot rice cultivation by utilizing eco enzyme produced as organic fertilizer liquid
A Case of Adrenoleucodystrophy: Newer Challenge to Rehabilitation
Authors: Newaz Fatema , Jashimuddin Jasmine , Nuery Nuzhat , Uddin Taslim
Published: January 2021

Adrenoleucodystrophy is a rare, genetic demyelinating disorder. Early onset of disease have rapid progression and worse prognosis. It may be associated with adrenal insufficiency. Not much treatment option as though rehabilitation is mainstream of management till death to reduce disability. We report the case of a 10-year-old boy with progressive weakness of all four limb and speech, swallowing difficulty, whose computerized tomography (CT) and Magnetic resonance imaging (MRI) scans showed unusually florid bilateral abnormalities. MRI showed hyperintensities on parieto-occipital lobe through corpus callosum and some biochemical imbalance on serum. The child was diagnosed as a case of Adrenoleukodystrophy and was presented in a clinical meeting for further managements including medical rehab. As this is a very rare case, it was a challenge to handle such type of patient with a course of combined rehabilitation program and discharged home.

Bangladesh Med J. 2019 May; 48 (2): 48-50
Antimicrobial Sensitivity Pattern of the isolated Uropathogens at a Teaching Hospital
Authors: Islam Md. Badrul , Yusuf Md. Abdullah , Hassan Munir , Akter Shimul
Published: January 2021

Background: Urinary tract infection is the most common infection occurs in both male and female.

Objective: This study was aimed to identify the uropathogens and their antimicrobial sensitivity pattern.

Methodology: This study was carried out in the Department of Microbiology at Dhaka National Medical College & Hospital, Dhaka from January 2018 to December 2018.

Result: A total of 1686 samples of urine were collected from suspected cases of urinary tract infections from Dhaka National Medical College & Hospital. Among them, 292 (17.32%) specimens showed significant bacterial growth. The most common uropathogens isolated were Escherichia coli.

Conclusion: In conclusion Gram negative bacteria is the commonest uropathogens isolated.

Journal of Science Foundation July 2019;17(2):42-45
Prospects of Quality Research and Evaluation of Education in Bangladesh
Authors: Rana Md. Masud , Gomes Kamol , Jahan Rounak , Khondoker Md. Fahmid Uddin , Hossain Md. Iqbal , Hoque AKM Fazlul
Published: January 2021

Education is the backbone of a nation. Only a splendid mentor can provide the educational system for the country by using his or her wisdom. Teachers are obligate to universal and quality education for all; they are central to shaping the minds and attitudes of the coming generations to deal with new global challenges and opportunities. In many countries, the quality of education is undermined by a severe deficit of teachers. The shortage of qualified teachers is hampering efforts in many countries to achieve quality education for all. Teachers are often lacking of good resources such as teaching materials, textbooks, proper training etc. The quality of teaching is cardinal to proper learning outcomes. This implies an education system that attracts and retains a magnificent teaching staff and supports teachers in the classroom, as well as in their continued professional development. Higher education with research is one of the important parts of the education system. The key aims of higher education are to generate the new knowledge, explore research works on different social and development issues, anticipate the needs of the economy and prepare highly skilled workers. In these contexts, higher education should be standard, welfare and sustainable development oriented. The present paper intends to analyze the higher education system of Bangladesh in the light of diversity, quality and accessibility.

Journal of Science Foundation 2019;17(2):46-53
Schwanomma of the Left Iliohypogastric Nerve: A Case Report and Technical Consideration
Authors: Alam Md. Shafiul , Haroon Kaisar , Farzana Tayseer , Ahmed Forhad , Taher Tania
Published: January 2021

Schwannomas are encapsulated tumors arising from Schwann cells of the nerve sheath, and are usually solitary sporadic lesions. The schwannoma of the ilio-hypogastric nerve especially in the retro-petoneal space is very rare. We are reporting a case of the schwannoma of the left ilio-hypagastric nerve over the psoas muscle. The diagnosis was done by ultarsonogrsphy and MRI. The histopathological study confirmed the diagnosis. The tumour was excised through retro-peritoneal approach. By this approach total excision of the tumour with preservation of ilio-hypogastric nerve is possible.

Journal of Science Foundation 2019;17(2):71-74
Impact of Climate Change in Rural Health: Bangladesh Perspective
Authors: Zeba Zebunnesa
Published: January 2021

Abstract Not Available

Journal of Science Foundation, January 2020;18(1):1-2
Anatomical Variation of Recurrent Laryngeal Nerve with Inferior Thyroid Artery: A Cross Sectional Study in Bangladeshi People
Authors: Islam Md Rabiul , Begum Tahmina , Islam Nazrul , Islam Md Moshabbirul
Published: January 2021

Background: Recurrent laryngeal nerve is varied anatomically with inferior thyroid artery.

Objective: The purpose of the present study was to observe the anatomical variation of recurrent laryngeal nerve with inferior thyroid artery among Bangladeshi people.

Methodology: This comparative cross-sectional study was conducted in the Department of Otolaryngology and Head-Neck surgery at Sylhet MAG Osmani Medical College Hospital, Sylhet, Bangladesh from January 2004 to December 2004 for a period of one (01) year. Patients whose recurrent laryngeal nerve was identified during thyroidectomy due to various pathological conditions of thyroid gland were selected as group I. Again, the dead body which were undergone dissection were designated as group II. All the patients whose recurrent laryngeal nerve and inferior thyroid artery were identified during total, near total, sub-total, hemithyroidectomised or lobectomised were included in this study.

Result: A total number of 32 patients were recruited for this study. On the left side nerve was found anteriorly in 2(10.53%), in between in 4(21.05%) and posteriorly in 13(68.42%). On the right side-nerve was found anteriorly in 7(30.43%), in between in 6(26.09%) and posteriorly in 10(43.48%). In this series nerve was seen posterior relation more than other two relations and anterior relation more on right side whereas posterior relation on left side, anterior relation more than in between relation on right side but reverse on left side. In group II On the left side nerve was found anteriorly in 2(6.25%), in between in 6(18.75%) and posteriorly in 24(75%). On the right side-nerve was found anteriorly in 8(25%), in between in 9(28.12%), and posteriorly in 10(46.88%).

Conclusion: In conclusion each recurrent laryngeal nerve lies posterior to the inferior thyroid artery in the majority of the occasions whereas the nerve lies anterior to the branches of the inferior thyroid artery less commonly except right side of both study group.

Journal of Science Foundation, January 2020;18(1):7-12
Triterpenoids Isolated from Stem Bark of Glochidion lanceolarium (Roxb.), Voigt
Authors: Kabir Selina , Haque Mohammad Rashedul , Chowdhury Abdullah Mohammad Sarwaruddin , Rashid Mohammad Abdur , Hasan Choudhury Mahmood
Published: January 2021

This paper presents the chemical investigation of the stem barks of Glochidion lanceolarium (Roxb.) Voigt, Euphorbiaceae. Classic phytochemical investigation of organic extracts of the aerial parts of Glochidion lanceolarium together with spectroscopic methods led to the isolation and characterization of three triterpenes, namely Epilupeol (1) Glochidonol (2), Glochidone (3).

Journal of Science Foundation, January 2020;18(1):13-18
Comparison of Serum Lipid Profiles of Women with or Without Hormonal Contraceptives Users at a Tertiary Care Hospital in Dhaka City
Authors: Khatun Kashifa , Shewly Naznin Rashid , Akter Shimul , Afroj Sultana , Yasmin Nilofar , Tawhida Fazle Noor-e , Nahar Shamsun
Published: January 2021

Background: Both oral and injectable hormonal contraceptives are the most popular type of birth control measures used in Bangladesh.

Objective: The purpose for the present study was to see the effects of hormonal contraceptives on serum lipid profiles.

Methodology: This was case-control study which was carried out in the Department of Obstetrics & Gynaecology at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from July 2004 to December 2005 for eighteen (18) months. Women of reproductive age group who had given the history of taking low-dose OCP containing 30 meg EE plus 150 meg LNG were included as case group and women who were presented without the history of hormonal contraceptives use were included as control group. Blood was collected from each woman in fasting state and serum was sent for estimation of serum lipids profiles like serum triglycerides, total cholesterol, LDL and HDL.

Result: The study included 40 women (control) who were not using OCP and 40 women (case) who were using OCP for more than one year. Comparison of age between control (31.75±4.85 years) and case (30.43±5.44 years) groups showed no significant difference (p>0.05). No significant difference with raised cholesterol levels (207.50±3.54 and 254.71± 45.54 mg/dl) was reported. Comparison of normal (136.16±39.46 and 154.05±35.33 mg/dl) and raised (229.00±24.52 and 246.32±35.98 mg/dl) triglyceride levels between control and case groups did not statistically significant. Comparison of normal and raised HDL levels did not show statistically any significant difference in control (32.07±3.02 mg/dL) and case (32.48±1.76 mg/dL) groups. Mean (±SD) of normal and raised levels of LDL was significantly high in case group. Normal LDL level was 82.71±26.82 and 111.05±15.40 mg/dl and raised LDL level was 138.55±3.03 and 188.82±40.37 mg/dL.

Conclusion: In conclusion use of low-dose OCP containing 30 meg EE plus 150 meg LNG significantly increases serum cholesterol, serum triglyceride and LDL-cholesterol levels but not HDL-cholesterol.

Journal of Science Foundation, January 2020;18(1):19-24
Aneurysmal Bone Cyst (ABC) Involving Petrous Apex Treated by Microsurgical Removal: A Case Report
Authors: Chowdhury Forhad H , Yusuf Mohammad Abdullah , Haque Mohammod Raziul
Published: January 2021

Aneurysmal bone cyst (ABC) is a benign progressive expansile bone lesion that usually involves often located in vertebrae, long tubular bones and flat bones. A small percentage of aneurysmal bone cysts arise from the skull base. Skull base involvement is very rare. Here, we describe a 22-year young man presented with diplopia, right sided facial paresis and right sided sensori-neural hearing loss. CT scan and MRI showed a right petrous apex skull base mass that was confirmed as ABC in histopathology after surgical removal.
Journal of Science Foundation, January 2020;18(1):25-28
When a single central incisor makes the difference for human identification – a case report
Authors: Silva Rhonan Ferreira , Picoli Fernando Fortes , Rodrigues Lívia Graziele , Silva Maria Alves Garcia Santos , Felisari Bárbara Forte , Franco Ademir
Published: January 2021

The analysis of dental features and patterns figures amongst the primary means for human identification established by the International Criminal Police Organization (INTERPOL). Differently from fingerprint and genetic analyses, forensic dentistry does not necessarily require a minimum number of similarities between antemortem and postmortem data. In other words, human identification could be achieved from the analysis of a single distinctive tooth or even from a single dental identifier. This study aims to report a case of dental human identification of a charred body. Police investigations were carried out and narrowed the scenario towards a single victim. Fingerprints were destroyed by the fire, hence the relatives of the victim were requested to provide any antermotem dental data. A panoramic radiograph was provided. Developing third molars were visible as well as the endodontic treatment, post and core, and the nonmetallic crown of the maxillary right central incisor (tooth #11). Postmortem radiographs were taken from the cadaver and revealed the same therapeutic dental identifiers found in tooth #11. The observed similarities and the lack of discrepancies between antemortem and postmortem data converged to the positive identification of the victim. This study illustrated the importance of Forensic Dentistry for complex cases of human identification, such as those exposed to fire. Especial attention is driven to the possibility of safely achieving positive human identification with the contribution of a single distinctive tooth.
O Impacto do Coronavírus (COVID-19) as atividades odontológicas: desafios econômicos e mentais
Authors: Gomes Pamela , Vieira Wellington , Daruge Rudiney , Recchioni Christian , Pugliese Camila , Villafort Rayssa , Cirilo Wilson , Barel Kelly Zaia
Published: January 2021

A infecção pelo novo Coronavírus 2019 (COVID-19) tem causado um grave impacto na saúde mundial, nos setores hospitalar e odontológico. O Brasil registrou o segundo maior número de pacientes e mais óbitos pelo coronavírus no mundo, perdendo apenas para os Estados Unidos. Os meios de comunicação social e científicas afirmaram que cirurgiões dentistas foram considerados grupo de risco para o covid-19, podendo atuar como vetor de transmissão direta e indireta em sua rotina de atendimento odontológico. Diante do ocorrido novas regras e hábitos amparados pela Organização Mundial de Saúde, alertaram sobre os atendimentos e procedimentos Odontológicos fossem realizados em caso de necessidade extrema; ou seja; apenas atendimentos de urgência e emergência, e casos eletivos fossem postergados, como medida de prevenção da disseminação do COVID-19, o distanciamento social adotado no Brasil pode ter consequências econômicas e psicossociais para a odontologia. Neste contexto, o presente estudo, os autores realizaram uma pesquisa nacional com cirurgiões dentistas brasileiros para avaliar o impacto da pandemia do novo Coronavírus sobre as atividades odontológicas.Um total de 246 cirurgiões dentistas responderam à pesquisa e os resultados indicaram que a grande maioria dos profissionais tiveram renda diminuída no período, seja pelos cancelamentos de consultas ou diminuição o número de atendimentos. Eles têm consciência que estão mais expostos, e por este motivo realizaram investimento científico e aquisição de equipamentos de proteção individual e essas junções de fatores podem provocar maior prejuízo no período de pandemia.
A importância das condições higiênico-sanitárias em abatedouros: Uma revisão de literatura
Authors: Santos Damaris Alves dos , Amaral Gabriela Vieira do , Sartori Fabio , Simas Jessica do Vale
Published: January 2021

Manter as condições higiênicas durante a produção é considerada peça chave na obtenção de alimentos inócuos. Os produtos cárneos podem ser contaminados por microrganismos durante a manipulação e o processamento. Após ter sido contaminada, a carne oferece condições para que os microrganismos se multipliquem, se tornando um potencial veiculador de bactérias patogênicas e uma ameaça à saúde do consumidor. A aplicação de programas de autocontrole como as boas práticas de fabricação, procedimento padrão de higiene operacional e análise de perigos e pontos críticos de controle são implantados com vistas a assegurar a inocuidade e a qualidade dos produtos. Por isso, é relevante avaliar as condições higiênicas e sanitárias dos estabelecimentos através do uso do checklist e coleta de amostras por meio do swab, e por meio das amostras é realizada a identificação de microrganismos indicadores como mesófilos aeróbios, enterobactérias e coliformes totais, que vão refletir as condições higiênicas e sanitárias do local e do produto.
Beyond coping with chronic NCDs: reflections on paradigms in one Brazilian Health Promotion Programme
Authors: Parreira Fernanda Ramos , Souza Marta Rovery de
Published: January 2021

This study provides reflections on the hybridisation of paradigms resulting from the creation of the Academy of Health Programme created by the Brazilian National Ministry of Health. This was a descriptive study, analysing the National Health Promotion Policy (first published in 2006 and revised in 2014), the National Strategic Action Plan to Battle Chronic Non-Communicable Diseases (NCDs) and the Academy of Health Programme (established by Ordinance no. 719/GM/MS in 2011). The scientific disputes seen during the development of the programme have had an impact on the practices it advises and on its implementation. We reflect that the Academy of Health Programme can and should create a space where, beyond the chronic NCDs, the model of dominator and dominated can be subverted and the transformation idealised by collective health through the health promotion movement can be made concrete.
Educação permanente visando à integralidade do cuidado na rede de saúde mental
Authors: Santos Silvia Cristina Pereira dos , Cortez Elaine Antunes , Valente Geilsa Soraia Cavalcanti , Assad Suellen Gomes Barbosa
Published: January 2021

Objetivo: Identificar as dificuldades enfrentadas pelos trabalhadores da rede de saúde mental e realizar ações de educação permanente, fomentando a discussão sobre o movimento de estruturação da Rede de Atenção Psicossocial. Método: Pesquisa-ação com aplicação de questionário e realização de oficinas de educação permanente com 22 trabalhadores da rede de saúde mental de Japeri, RJ, cujos dados foram tratados por análise de conteúdo temática. Resultados: Foram analisadas quatro categorias: Desafiando gigantes: estrutura do trabalho na saúde mental; “Despreparo” profissional e a construção na reflexão da prática: a grande virada; Articulação: integralidade e intersetorialidade, caminho para romper as desigualdades; Desdobramentos da pesquisa e das oficinas de Educação Permanente em Saúde: a reflexão na ação gerou construção. Conclusões e implicações para a prática: A partir do processo de reflexão-na-ação, os entraves que fragmentam os serviços de saúde mental foram analisados, permitindo a elaboração de propostas coletivas de intervenção que promovam o cuidado integral aos usuários.
Panorama da contaminação ambiental por agrotóxicos no estado do mato grosso: risco para o abastecimento urbano
Authors: Novais Cleidiane Moraes , Queiroz Tadeu Miranda de , Seabra Júnior Santino
Published: January 2021

O estado do Mato Grosso tem a maior participação em vendas de agrotóxicos do Brasil, como consequência da expansão agrícola sofrida nos últimos anos. Fundamentando-se no risco de exposição humana a esses produtos pela ingestão de água contaminada, o presente artigo teve como objetivo identificar, analisar e descrever as contribuições científicas encontradas na literatura sobre o panorama da contaminação dos mananciais utilizados para abastecimento urbano mato-grossense, as metodologias analíticas para tratamento da contaminação e as políticas públicas voltadas para seu monitoramento. Constatou-se que apesar de existir legislações vigentes de controle da qualidade da água, há falhas no cumprimento e no monitoramento desses princípios ativos, motivo que é associado ao alto custo para o tratamento adequado, resultando assim, em diversos transtornos ambientais e sociais.
The role of type 2 Diabetes mellitus as a risk factor for Alzheimer's and Parkinson's diseases
Authors: Rocha Kellen Mariane Athaide , Goulart Aline da Silva , Costa Márcio Tavares , Salgueiro Andréia Caroline Fernandes , Folmer Vanderlei
Published: January 2021

Currently, one of the most significant health problems is the increased incidence of obesity and type 2 Diabetes mellitus (DM2). The most recent epidemiological and clinical research studies have indicated that low physical activity, as well as many genetic and environmental factors are the main causes of these metabolic disorders. It is widely recognized that insulin resistance plays a key role in the development of DM2, disrupting not only the functioning of peripheral tissues, but also the brain. Insulin plays a critical role in the central nervous system participating in neuronal survival, neuroplasticity, memory and cognitive functions. In addition, peripheral insulin resistance results in loss of brain function, which indicates a strong relationship between metabolic disorders, cognitive impairment and the emergence of neurodegenerative diseases. There are links between these different pathologies, such as increased oxidative stress, neuroinflammation, changes in glucose metabolism as well as insulin resistance. Advances in the knowledge of these links may contribute to the development of treatments for the prevention of these pathological events. Based on the above, this study aimed to review the mechanisms associated with DM2 in the development of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s diseases.
Proximal composition, caloric value and price-nutrients correlation of comercial cuts of tambaqui (Colossoma macropomum) and pirarucu (Arapaima gigas) in diferente body weight classes (Amazon: Brazil)
Authors: Dantas Filho Jerônimo Vieira , Cavali Jucilene , Nunes Carla Taveira , Nóbrega Beatriz Andrade , Gasparini Lucas Rodrigues da Fonseca , Souza Maria Luiza Rodrigues de , Porto Marlos Oliveira , Rosa Bruna Laurindo , Gasparotto Paulo Henrique Gilio , Pontuschka Rute Bianchini
Published: January 2021

The aimed of the study was to evaluate the caloric value as a function of the proximal composition and correlate the selling price with the nutritional values ​​of commercial cuts of tambaqui (Colossoma macropomum) and pirarucu (Arapaima gigas) in different weight classes. The sample collections were performed in two processing units located in the state of Rondônia, Brazil. Were 200 tambaquis in five weight classes were studied. And, were 77 pirarucus were studied in seven weight classes. The design was completely randomized, with processing carried out in triplicate. The Kruskal-Wallis test (α=0.05) was used to compare the averages and the Spearman correlation (ρ) between price and nutrients. The commercial cuts with the highest caloric value were the tambaqui filet (145.70 kcal/100g) and the pirarucu filet mignon (119.11 kcal/100g) (p<0.05). And the less caloric commercial cuts were steak of tambaqui (100.47 kcal/100g) and pirarucu loin 102.01 kcal/100g) (p<0.05). It was also observed that the variables caloric value and protein content did not correlate with the price of the kilo of fish for the different commercial cuts, which leads to infer that, possibly, the sensorial, market and cultural factors were responsible for the price variations. Regarding the caloric value according to the composition of the tambaqui, the Class 4 was the most efficient category for production and commercialization. And in the composition of the pirarucu, the Class 4 presented satisfactory values of proteins and lipids and a good percentage of mineral matter.
Fatores relacionados à intensificação do trabalho da enfermagem hospitalar
Authors: Arboit Éder Luís , Camponogara Silviamar , Freitas Etiane de Oliveira
Published: January 2021

Objetivo: identificar os fatores relacionados à intensificação do trabalho da enfermagem no ambiente hospitalar. Método: estudo de revisão integrativa da literatura, cujo levantamento bibliográfico foi realizado em agosto e setembro de 2019, em seis bases de dados da área da saúde. A amostra esteve constituída por 20 artigos. Realizou-se a sistematização dos dados pela técnica de Análise de Conteúdo Temático. Resultados: a intensificação do trabalho da enfermagem está relacionada aos fatores institucionais/laborais com foco na precarização do trabalho, sub dimensionamento de pessoal com consequente aumento da carga de trabalho, fragilidades nas condições e relações de trabalho, extensão e/ou duplicidade na jornada de trabalho e, neste interim, a realização de varias tarefas de modo simultâneo. Dentre os fatores humanos, destaca-se a ocorrência de alterações físicas e emocionais nos trabalhadores, aumento do estresse, exaustão, fragilidade nas relações e aumento do absenteísmo.  Já em relação aos fatores clínicos, estão relacionados com o aumento nas taxas de admissões a altas hospitalares, aumento nas taxas de mortalidade dos pacientes e tempo de permanência hospitalar. Conclusão: evidencia-se que a intensificação do trabalho da enfermagem no ambiente hospitalar advém de fatores institucionais/laborais, fatores humanos e aqueles relacionados com o quadro clínico dos pacientes. O estudo poderá contribuir poderá subsidiar e fomentar discussões sobre a temática, possibilitando à formulação de estratégias direcionadas a saúde do trabalhador e melhoria da qualidade dos cuidados oferecidos aos pacientes.
Delimitación de las potenciales zonas de recarga-caso de estudio: acuífero multicapa del eje bananero del Urabá Antioqueño-Colombia
Authors: Betancur-Vargas Teresita , Duque-Duque Jhon Camilo , Martínez-Uribe Cristina , Garcia-Giraldo Daniel Alejandro , Villegas-Yepes Pedro Pablo , Paredes-Zuñiga Vanessa
Published: January 2021

El conocimiento del Modelo Hidrogeológico Conceptual permite adoptar y adaptar un procedimiento adecuado para cada caso de estudio, considerando acuíferos libres y acuíferos confinados, teniendo en cuenta las diferencias estructurales entre rocas duras, rocas blandas y depósitos no consolidados; y evaluando el rol de la textura y la capacidad de infiltración del suelo, en la dimensión de la función de la recarga directa. Para el sistema hidrogeológico del Eje Bananero del Urabá Antioqueño- Colombia la tarea de entender la recarga puso de manifiesto la necesidad de establecer una escala de calificación para evaluar el factor estructural en rocas blandas y depósitos no consolidados y definir categorías de importancia, basados en propiedades texturales y tasas de infiltración para las zonas de recarga directa difusa en acuíferos libres; también se determinó un procedimiento para delimitar zonas asociadas a las unidades hidrogeológicas que subrayasen a los acuíferos confinados.
Relación entre la percepción del riesgo biológico y la accidentalidad laboral en un hospital Colombiano, 2019
Authors: Uribe-Salazar Johny Andrés , Bedoya-Carvajal Oscar Augusto , Vélez-Gómez Diego Enrique
Published: January 2021

La percepción del riesgo es un factor importante asociado al error humano, e involucrado en la ocurrencia de accidentes laborales. Objetivo: Explicar la relación que existe entre la percepción del riesgo biológico y la accidentalidad laboral de los empleados de un hospital de Antioquia, en el año 2019. Metodología: Estudio explicativo transversal que empleó la metodología EPRO (Evaluación de Percepción de Riesgo Ocupacional) y el software RISKPERCEP a través de una encuesta estructurada a todos los trabajadores (N=50) de la institución. La información estadística se analizó con el software SPSSv24. Resultados: Se encuentra un perfil de subestimación del riesgo biológico laboral en las diferentes áreas de la institución. A la accidentalidad laboral se asocian factores como el tiempo desarrollando la misma actividad y la percepción del estado de salud. Conclusión: Los trabajadores con mayor experiencia y exposición al riesgo biológico laboral subestiman el riesgo.
Emerald Ash Borer Specific Gene Silencing Has No Effect on Non-target Organisms
Authors: Pampolini Flavia , Rieske Lynne K.
Published: January 2021

The sequence complementarity of the RNA interference (RNAi) pathway allows for targeted suppression of genes essential for insect survival, and enables development of pest management strategies specific to a given species while reducing the likelihood of adversely impacting non-target organisms (NTOs). The feasibility of manipulating the RNAi pathway to cause mortality in the highly invasive emerald ash borer (EAB) has been demonstrated. Here the spectrum of activity of three double stranded RNAs (dsRNAs) targeting the geneshsp, shi, andsn-rnpin EAB was evaluated in model insects representing five functional guilds including herbivore, predator, detritivore, pollinator, parasitoid; the last represented by the classical biological control agents currently deployed for EAB management in North America. All NTOs were exposed to EAB-specific dsRNAs in diet bioassays that measured potential lethal effects. Gene expression andin silicoanalysis were also assessed on NTOs for which gene sequences were publicly available. Bioassays demonstrated no lethal effects on our model insects, suggesting a narrow spectrum of activity for the three EAB-specific dsRNAs evaluated. The gene expression andin silicoanalyses suggest potential sublethal effects on our model pollinator; however we found no effects on insect survival. Overall, our results suggest no adverse effects of the RNAi strategy targeting EAB genes on the survival of the selected non-target organisms we evaluated. The results from this study provide guidance for future RNAi risk analyses that will allow this technology to move forward to a deployment stage.
Applications of Microbial β-Mannanases
Authors: Dawood Aneesa , Ma Kesen
Published: January 2021

Mannans are main components of hemicellulosic fraction of softwoods and they are present widely in plant tissues. β-mannanases are the major mannan-degrading enzymes and are produced by different plants, animals, actinomycetes, fungi, and bacteria. These enzymes can function under conditions of wide range of pH and temperature. Applications of β-mannanases have therefore, been found in different industries such as animal feed, food, biorefinery, textile, detergent, and paper and pulp. This review summarizes the most recent studies reported on potential applications of β-mannanases and bioengineering of β-mannanases to modify and optimize their key catalytic properties to cater to growing demands of commercial sectors.
System Identification and Seismic Performance Assessment of Representative RC Buildings in Kathmandu Valley
Authors: Dhakal Rajan , Rupakhety Rajesh , Gautam Dipendra
Published: January 2021

To identify dynamic characteristics of representative reinforced concrete frame buildings with brick infills, ambient vibration measurements were taken in two four-storied buildings—one situated in soft soil and the another in stiff soil. Non-parametric as well as parametric system identification (SID) algorithms were used to estimate vibration frequencies and damping of the two buildings. The numerical models of the buildings were created using the finite element method. The modal frequencies and damping ratios obtained from ambient measurements were used to calibrate and tune the finite element models. The comparison between measured vibration frequencies and those obtained from finite element model highlights the need for accuracy in modeling assumptions, in particular, consideration of the stiffness of infill walls and the flexibility of foundation soil. The finite element models calibrated with SID results were used to estimate the response of the two buildings when subjected to strong ground motion recorded at different places in the Kathmandu Valley during the 2015 Gorkha earthquake. The results show that not considering flexibility of foundation and stiffness of infill walls, as is commonly done in engineering practice, can lead to inaccurate estimates of seismic demand.
Interferon-γ and Hypoxia Priming Have Limited Effect on the miRNA Landscape of Human Mesenchymal Stromal Cells-Derived Extracellular Vesicles
Authors: Peltzer Juliette , Lund Kyle , Goriot Marie-Emmanuelle , Grosbot Marion , Lataillade Jean-Jacques , Mauduit Philippe , Banzet Sébastien
Published: January 2021

Mesenchymal stromal cell (MSC)-based cell therapy has received great interest in regenerative medicine. Priming the cells during the culture phase can improve their efficacy and/or survival after injection. The literature suggests that MSC extracellular vesicles (EV) can recapitulate a substantial part of the beneficial effects of the cells they originate from, and that micro-RNAs (miRNAs) are important players in EV biological action. Here, our aim was to determine if two classical priming methods of MSC, interferon-gamma (IFNγ) and hypoxia (HYP), could modify their EV miRNA content. Human bone marrow MSCs (BM-MSCs) from five healthy donors were cultured with IFNγ or in HYP or in control (CONT) conditions. The conditioned media were collected after 48 h in serum-free condition and EV were isolated by ultracentrifugation. Total RNA was isolated, pools of CONT, IFN, and HYP cDNA were prepared, and a miRNA profiling was performed using RT-qPCR. Then, miRNAs were selected based on their detectability and measured on each individual EV sample. Priming had no effect on EV amount or size distribution. A set of 81 miRNAs was detected in at least one of the pools of EVs. They were measured on each individual sample; 41 miRNAs were detected in all samples. The principal component analysis (PCA) failed to discriminate the groups. HYP induced a significant decrease in EV hsa-miR-34a-3p content and IFN induced a significant increase in five miRNAs (hsa-miR-25-3p, hsa-miR-106a-5p, hsa-miR-126-3p, hsa-miR-451a, and hsa-miR-665). Taken together, we found only limited alterations in the miRNA landscape of MSC EV with a high inter-individual variability.
gga-miR-148a-5p-Targeting PDPK1 Inhibits Proliferation and Cell Cycle Progression of Avain Leukosis Virus Subgroup J (ALV-J)-Infected Cells
Authors: Yu Heling , Xu Hengyong , Yan Chaoyang , Zhu Shiliang , Lan Xi , Lu Yuxiang , He Qijian , Yin Huadong , Zhu Qing , Zhao Xiaoling , Li Diyan , Liu Yiping , Wang Yan
Published: January 2021

Avian leukosis virus subgroup J disease (ALV-J) is a contagious and immunosuppressive avian disease caused by ALV-J virus. Although miRNA participate in various biological processes of tumors, little is known about the potential role of miRNA in ALV-J. Our previous miRNA and RNA sequencing data showed that the expression of gga-miR-148a-5p was significantly different in ALV-J-infected chicken spleens compared with non-infected chickens. The aim of this study was to investigate the functional roles of gga-miR-148a-5p and identify downstream targets regulated by gga-miR-148a-5p in ALV-J-infected chickens. We found that the expression of gga-miR-148a-5p was significantly downregulated during ALV-J infection of chicken embryo fibroblasts (CEF). Dual luciferase reporter assays demonstrated that PDPK1 is a direct target gene of gga-miR-148a-5p. In vitro, overexpression of gga-miR-148a-5p significantly promoted ALV-J-infected CEF cell proliferation, included cell cycle, whereas inhibition of gga-miR-148a-5p had an opposite effect. Inhibition of PDPK1 promoted the proliferation of ALV-J-infected cells but had no effect on the activity of NF-κB. Together, these results suggested that gga-miR-148a-5p targets PDPK1 to inhibit the proliferation and cell cycle of ALV-J-infected CEF cells. Our study provides a new understanding for the tumor mechanism of ALV-J infection.
Two Types of Contact Between Lipid Droplets and Mitochondria
Authors: Cui Liujuan , Liu Pingsheng
Published: January 2021

Lipid droplets (LDs) and mitochondria are essential organelles involved in cellular lipid metabolism and energy homeostasis. Accumulated studies have revealed that the physical contact between these two organelles is important for their functions. Current understanding of the contact between cellular organelles is highly dynamic, fitting a “kiss-and-run” model. The same pattern of contact between LDs and mitochondria has been reported and several proteins are found to mediate this contact, such as perilipin1 (PLIN1) and PLIN5. Another format of the contact has also been found and termed anchoring. LD-anchored mitochondria (LDAM) are identified in oxidative tissues including brown adipose tissue (BAT), skeletal muscle, and heart muscle, and this anchoring between these two organelles is conserved from mouse to monkey. Moreover, this anchoring is generated during the brown/beige adipocyte differentiation. In this review, we will summarize previous studies on the interaction between LDs and mitochondria, categorize the types of the contacts into dynamic and stable/anchored, present their similarities and differences, discuss their potential distinct molecular mechanism, and finally propose a working hypothesis that may explain why and how cells use two patterns of contact between LDs and mitochondria.