bluuebunny/crossref_metadata_2025 huggingface dataset:
Determination of Thermodynamic Protonation Constants of Some Selective Serotonin Reuptake Inhibitors in Water-Acetonitrile Binary Mixtures
Authors: DALDAL Yaşar Doğan , ÇUBUK DEMİRALAY Ebru
Published: October 2022

Bu çalışmada, trisiklik antidepresanlara alternatif olarak kullanılan selektif serotonin geri alım inhibitörleri (SSRİ)’nden sitalopram, fluvoksamin ve sertralinin su-asetonitril ikili karışımında, ters faz sıvı kromatografik (RPLC) yöntemle alıkonma davranışı incelenmiştir. Kromatografik analizler, mobil faz pH’sı 6,5 ila 10,5 arasında değişen, %45-%55 (h/h) arasında asetonitril içeren asetonitril-su ikili karışımlarında gerçekleştirilmiştir. Çalışma boyunca, kolon sıcaklığı ve akış hızı sırasıyla, 30 oC ve 0,8 mL/dakika’da sabitlenmiştir. Bu çalışmada, mobil faz pH değerlerine karşı bileşiklerin alıkonma değerlerinin lineer solvasyon enerjisi ilişkisi (LSER) yaklaşımıyla değerlendirilmesiyle teorik alıkonma değerleri hesaplanmıştır. Ayrıca farklı pH değerlerindeki mobil fazların aktivite katsayıları değerleri hesaba katılarak doğrusal olmayan regresyon programıyla bileşiklerin termodinamik protonasyon sabitleri ((_s^s)〖pK〗_a) belirlenmiştir. Hidrofobik özellikteki bileşiklerin (_s^s)〖pK〗_a değerleri kullanılarak iki farklı yaklaşımla su ortamındaki protonasyon sabiti değerleri hesaplanmıştır. Çalışma sonunda her iki ekstrapolasyon yönteminden elde edilen sonuçların birbiriyle uyumlu olduğu görülmüştür.
La comunicación estratégica de riesgo y crisis en los gobiernos autónomos descentralizados del Ecuador
Authors:   , Molina Estrella María Eugenia
Published: October 2022

La presente investigación busca aportar al conocimiento desde las distintas aristas académicas de la comunicación de riesgo y crisis; este trabajo se enmarca desde la óptica de la comunicación estratégica para su prevención, manejo y gestión, tomando en cuenta que la comunicación de riesgo y crisis constituye una temática nueva en el ámbito de la comunicación organizacional a nivel de América Latina en general y del Ecuador de forma específica. Desde esta perspectiva, esta tesis pretende ser un aporte e insumo para que tanto las autoridades como la ciudadanía conozcan, valoren y se apropien de la importancia de esta especialidad de la comunicación y que esta investigación se constituya en un material de consulta para la gestión del riesgo y la crisis en temáticas relacionadas con fenómenos naturales, dando principal atención a la vida y la seguridad mediante la gestión integral del riesgo, realizar mitigación de vulnerabilidades y amenazas y gestionando la crisis de manera técnica. La comunicación y la educación son clave para lograr que los fenómenos naturales no se desencadenen en desastres o catástrofes de lamentables consecuencias. Esta obra concentra la importancia y originalidad de la temática propuesta, el aporte sobre los estudios de comunicacón de crisis que van tomando fuerza y siendo cada vez más necesarios en la nueva perspectiva teórica de la comunicación.
AKTIVITAS ANTIBAKTERI EKSTRAK DAUN AKASIA (Acacia auriculiformis) TERHADAP PERTUMBUHAN BAKTERI Bacillus sp., Staphylococcus aureus DAN Escherichia coli
Authors: Hidayah Nurul , Nurdin Gaby Maulida , Ameliani Nur Afia
Published: October 2022

Meningkatnya kejadian resistensi bakteri terhadap antibiotik, mendorong pemanfaatan obat herbal dalam mengobati penyakit infeksi. Daun Acacia auriculiformis diketahui memiliki senyawa metabolit yang dapat menghambat pertumbuhan bakteri Gram positif dan negatif. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri ekstrak daun A. auriculiformis terhadap pertumbuhan bakteri Bacilus sp., Staphylococcus aureus dan Escherichia coli secara in vitro. Penelitian ini dilakukan dengan mengekstrak daun A. auriculiformis menggunakan pelarut etanol. Uji daya hambat ekstrak daun A. auriculiformis dilakukan dengan metode difusi sumur. Adanya aktivitas antibakteri ditunjukkan dengan adanya zona bening di sekitar sumur. Hasil penelitian menunjukkan bahwa ekstrak daun A. auriculiformis memiliki kemampuan menghambat pertumbuhan bakteri Bacillus sp. dan Staphylococcus aureus dengan kategori daya hambat tergolong kuat. Ekstrak daun A. auriculiformis tidak mampu menghambat pertumbuhan bakteri Escherichia coli. Uji golongan senyawa dengan metode skrining fitokimia menunjukkan bahwa daun akasia mengandung senyawa flavonoid dan tanin yang bersifat antibakteri.
Karakteristik Perilaku Kucing Domestik
Authors: Ngitung Rosdiana
Published: October 2022

Kucing domestic (Felis catus) memiliki pola perilaku yang berbeda dengan hewan lainnya. Perilaku ini terjabar dalam 10 pola perilaku yaitu perilaku ingestif, perilaku seks, perilaku eliminative, perilaku investigative, perilaku agonistic, perilaku allelomimetic, perilaku mencari perlindungan, perilaku epimeletic, perilaku et-epimeletic dan perilaku maladaptive. Perilaku ini terjadi secara alamiah maupun karena diajarkan kepada kucing. Penelitian kali ini dilakukan untuk mengetahui kesepuluh pola perilaku pada kucing yang dikaji melalui studi pustaka atau kajian literature dengan mencari sumber terkait dengan perilaku kucing domestik. Sehingga, diperoleh hasil bahwa kucing memiliki pola perilaku yang spesifik pada kesepuluh pola perilaku tersebut.
Trend Penelitian IPA Berbasis Etnosains Melayu Riau : Sistematic Literatur Review
Authors: Pane Indry Zusniati , Amalia Delfa Vioni , Ilhami Aldeva
Published: October 2022

Penelitian ini bertujuan untuk menganalisis kearifan lokal di Riau berbasis etnosains. Penelitian ini menggunakan metode SLR (Sistematic Literatur Review) dengan menggunakan diagram PRISMA. Teknik analisis yang digunakan yaitu dengan cara mengumpulkan data dilakukan dengan mengidentifikasi atau menelaah semua artikel yang memiliki topik penelitian yang sama pada penelitian ini. Artikel yang digunakan pada penelitian ini sebanyak 3 artikel jurnal dan 3 skripsi. Dari penelitian ini didapatkan bahwa kearifan lokal ada tiga yaitu tradisi manongkah kerang di Kabupaten Indragiri Hilir, kearifan lokal tentang teknik penangkapan burung di Desa Rumbio, kearifan lokal hutan larangan adat Rumbio. Hasil penelitian ini menunjukkan bahwa trend penelitian IPA yang berbasis Etnosains ada 2 yaitu kearifan lokal hutan larangan adat Rumbio dan kearifan lokal manongkah kerang di Indragiri Hilir. Dengan demikian dapat disimpulkan bahwa kearifan lokal yang ada di provinsi Riau penelitiannya ada yang berbasis Etnosains.
Spatial representation of mobile operators’ data on pulsations of the Central Administrative District of Moscow population during 2019–2020 in the context of studying the vulnerability of the population to emergencies
Authors: Bobrovskiy Roman , Babkin Roman , Bereznyatskiy Alexander
Published: October 2022

The high concentration of residents of large cities in certain localities requires a rethinking of existing methods for assessing the vulnerability of the population to various types of threats and to ways of mapping them. Moscow, being a megalopolis and the center of the largest European agglomeration, forms a zone of an increased level of natural and man-made risk for citizens, primarily due to spatial concentration and mobility of the population. The risks are especially high for the central part of Moscow (in the work considered within the boundaries of the Central Administrative District—CAO). The high business and cultural and entertainment attractiveness of this part of the capital contributes to the highest gradients of pulsations of crowding within the daily and weekday-weekend cycles. The present study is devoted to the qualitative display of these changes. To obtain the most detailed spatio-temporal information, the data of mobile operators on the localization of subscribers aggregated for January 2019–January 2020 were used. The paper tests the approach of displaying changes in the density characteristics of the population of the territory of the CAO districts by superimposing information on a pallet of 500 by 500 meters consolidated for fractional (30 minutes) time intervals of data (median population for all days of the year, separately for weekdays, weekends, and holidays). It was shown that for the central part of the capital, the gradients of daily pulsations on weekdays reach 220–320 %, and on weekends — 120–160 %. At the same time, in contrast to the sleeping areas of the city, seasonal fluctuations are much weaker here. The concentration of various cultural and entertainment activities in such areas as Tverskoy, Arbat and Yakimanka leads to pronounced festive changes in crowding, which are about 50 % stronger than the standard weekend pulsations.
Prevention of deviant behavior of adolescents in the context of spiritual and moral education
Authors: Filipenko Elena
Published: October 2022

Abstract: The article deals with one of the urgent problems of modern educational practice – the problem of prevention of deviant behavior of adolescents as a necessary condition for the progressive and safe development of society and civilization as a whole. When examining the problem under consideration, the authors focus on the study of the phenomenon of deviant behavior, since the effective implementation of preventive educational practice requires a deeper and more comprehensive understanding of the essence of deviant behavior. On the basis of this statement, the authors have studied the main types of deviant behavior, its leading socio-psychological determinants, the system of the most adopted scientific approaches to the interpretation of this scientific category, as well as pedagogical strategies for the prevention of this type of behavior. The complex of applied forms and methods of pedagogical prevention crucially determines the effectiveness of preventive measures, and therefore, this aspect is also reflected in our article. Particular attention is paid to the problem of spiritual and moral education of the younger generation. Achieving a high level of spirituality and morality both of an individual and society is considered as a kind of unconditional guarantee of preventive work to prevent adolescent deviance.
Victimization of the population of modern Russia. Deviantological view
Authors: Ogar Tatyana , Kharlamov Valentin
Published: October 2022

Abstract: In modern Russia many people become victims of crimes every day. Insufficient adaptation of Russians to ensure personal security is caused by their personal criminal vulnerability (victimization). The victimological situation in the country, without exaggeration, can be assessed as extremely tense, revealing the need to create a system of measures to ensure the proper security of citizens and legal entities. The solution of this problem is impossible without a deep study of the real state of victimization of the population. On the basis of official criminal statistics, the authors present the dynamics, state, structure of the negative consequences of crime. The assessment of material damage from crimes committed in the country is given. The specificity of arrays of victims of crimes in transport is shown in comparison with the general array of victims of crimes. The geography of criminal victimization is reflected. The nature of latent victimization is investigated. The ratio of criminal victims among legal entities and individuals is considered. The results of the proposed analysis of criminal victimization of the population will make it possible to make management decisions aimed at effective fighting crime.
Tanggung Jawab Sosial Perusahaan dan Akses Pendanaan
Authors:   Landis & Kadwell Indonesia, Jakarta, Tandiawan Wendy
Published: October 2022

Abstract: Purpose: Purpose of this research is to find out the effect of Corporate Social Responsibility (CSR) on cost of equity and capital constraint, as well as the effect of the cost of equity itself to capital constraint. Moreover, this research attempts to see the relationship effect of the exogenous variable towards the endogenous variable, and to test the position of cost of equity variable as an intervener. Methodology/approach: Type of this research is descriptive and verification, where the focus is to find the effect and amount of the effect itself between the exogenous and endogenous variable. In case of the cost of equity as an intervening variable, multiple linear regression with Two Stage Least Squareis used. The sampling method for this research is a purposive sampling. To see the effect between the variables, t-test and F-test are used. Subjects of this research are the listed manufacturing companies in Indonesia Stock Exchange, and the objects are Corporate Social Responsibility as the exogenous variable that consist of stakeholder engagement and CSR Disclosure as proxy, and cost of equity as the endogenous variable, as well as the capital constraint. Results/findings: The research result proves that the first structural model to see the effect of CSR on cost of equity partially or simultaneously is not significant. As the opposite, the second model to test the effect of CSR on capital constraint has significant relationship partially and simultaneously. Nevertheless, cost of equity is not proven to be an intervening variable for CSR and capital constraint. Keywords: 1. corporate social responsibility 2. capital constraint 3. cost of equity 4. stakeholder engagement 5. disclosure
Perkawinan Nglangkahi pada Masyarakat Adat Jawa dalam Perspektif Hukum di Indonesia
Authors: Rahma Laela Novitri Ervia
Published: October 2022

Sebuah kelompok masyarakat tentunya memiliki kebiasaan khusus yang diyakini sebagai sesuatu yang baik dan dilakukan secara berulang dan turun temurun dan terkadang mengandung suatu sanksi yang disebut sebagai sebuah adat. Di dalam masyarakat Jawa dikenal sebuah adat terkait dengan perkawinan yang dikenal dengan perkawinan nglangkahi. Perkawinan nglangkahi merupakan perkawinan yang dilaksanakan dengan mendahului kakak mempelai. Menurut masyarakat Jawa, hal ini merupakan sesuatu yang kurang baik untuk dilakukan, maka dari itu terdapat sanksi yang diberikan kepada mempelai apabila melaksanakan perkawinan nglangkahi. Kajian dalam tulisan ini membahas mengenai keterkaitan antara hukum nasional di Indonesia dengan perkawinan nglangkahi pada masyarakat Jawa beserta dengan sanksinya. Studi yang digunakan menggunakan studi hukum adat dengan melihat juga dari sisi antropologis dan sosiologis yang ada dalam kehidupan masyarakat Jawa.
Penyimpangan Asas Itikad Baik dalam Perjanjian Sewa Menyewa Kendaraan dalam Perspektif Hukum Pidana dan Perdata
Authors: Christy Maria Acynta
Published: October 2022

Tujuan penulisan ini adalah untuk mengetahui bentuk penyimpangan asas itikad baik dalam perjanjian sewa menyewa kendaraan,dan peranan asas itikad baik dalam perjanjian sewa menyewa kendaraan dalam perspektif hukum perdata dan pidana. Penelitian ini merupakan penelitian hukum normatif, dilakukan dengan cara menelaah data sekunder yang diperoleh melalui penelitian dengan cara mempelajari dan mengkaji buku-buku, salinan putusan pengadilan, jurnal, hasil studi dan/atau penelitian terdahulu, dan peraturan perundang-undangan yang berkaitan dengan permasalahan. Bahan penelitian tersebut dianalisis dengan metode kualitatif dan ditampilkan dengan menggunakan metode deskriptif. Hasil penelitian menunjukan bahwa Pemerintah dan lembaga bantuan hukum perlu memberikan sosialisasi kepada para pelaku usaha mengenai prosedur yang aman dalam menjalankan usaha sewa menyewa kendaraan, seperti: bagaimana membuat perjanjian yang melindungi hak-hak pelaku usaha dan konsumen, serta bagaimana upaya hukum yang dapat ditempuh oleh para pihak yang dirugikan karena adanya perbuatan melawan hukum oleh konsumen/ pelaku usaha yang beritikad tidak baik. Masyarakat dan pihak-pihak yang terlibat di dalam perjanjian sewa menyewa kendaraan harus berhati-hati dalam melakukan sewa menyewa kendaraan dengan terlebih dahulu meneliti subjek dan objek perjanjian pada tahap offering and acceptance, sebelum menandatangani perjanjian. Para pihak yang terlibat di dalam perjanjian sewa menyewa kendaraan sebaiknya merumuskan perjanjian secara tertulis agar memberikan kepastian hukum bagi para pihak dan sebagai alat bukti jika terjadi sengketa di kemudian hari.
Problematika Wanprestasi Atas Perjanjian Arisan Online
Authors: Juang Nurhadi Ahmad , Hidayat Muhammad Kevin , Andriati Syarifah Lisa
Published: October 2022

Pada era digital saat ini marak adanya arisan online dikalangan masyarakat Indonesia. Jika pada umumnya arisan itu harus dengan pertemuan, namun tidak dengan jenis arisan ini, kegiatannya hanya melalui media sosial atau wadah untuk menghubungkan para peserta arisan online. Dimana perjanjian arisan online yang telah disepakati berlaku layaknya undang-undang bagi para pihak. Sehingga apabila salah satu pihal lalai dan tidak dapat memenuhi prestasi atau melakukan kewajibannya, maka pihak tersebut dapat dikatakan telah melakukan perbuatan wanprestasi. Pada umumnya wanprestasi baru muncul ketika ada pernyataan lalai dari kreditur maupun debitur. Pada arisan online, kreditur pada permasalahan ini adalah orang yang seharusnya menerima uang dalam arisan dan pihak debitur pada arisan online ialah orang yang seharusnya memberi uang. Jadi, pernyataan lalai ini mucul sebagai peringatan kepada debitur ataupun kreditur untuk segera melaksanakan kewajibannya dengan tenggang waktu yang telah ditentukan. Adapun kasus yang menjadi pendekatan pada tulisan ini adalah kasus wanprestasi terhadap perjanjian arisan online pada Putusan Nomor 18/Pdt.G.S/2021/PN Sby, merupakan salah satu bentuk kasus wanprestasi arisan online yang masih baru saja terjadi. Dimana tergugat selaku peserta arisan online tidak membayarkan uang iuran bulanan sesuai dengan yang telah diperjanjikan. Sehingga berdasarkan pertimbangan majelis hakim, tergugat telah dinyatakan melakukan wanprestasi dan gugatan penggugat dikabulkan untuk sebagian. Jenis penelitian yang digunakan adalah yuridis normatif. Penulisan jurnal ini didasarkan pada masalah tentang apa sebenarnya yang dapat menyebabkan terjadinya wanpretasi atas perjanjian arisan online dan bagaimana peran pemerintah untuk mengatasinya. Terhadap pencegahan dan perlindungan berupa regulasi saja tidak cukup sebagai upaya dalam melindungi dan menjamin hak para pihak dalam perjanjian arisan online. Perlu adanya sebuah langkah yang dapat digunakan sebagai upaya preventif demi meminimalisir adanya wanprestasi atas perjanjian arisan online. Peran pemerintah yang bersifat preventif sangat diperlukan untuk mengatasi permasalahan-permasalahan arisan online yang semakin marak terjadi saat ini.
Hak waris Surrogate Mother dari Anak Hasil Sewa Rahim Ditinjau dari Aspek Perdata
Authors: Az Zahra Nur Ina
Published: October 2022

Sewa rahim (surrogate mother) merupakan sebuah inovasi di bidang kesehatan dan teknologi yang memungkinkan pembuahan terjadi di luar tubuh dan ditanamkan lagi dalam rahim perempuan lain. Penemuan teknologi ini menambah daftar bagi pasangan suami isteri yang tidak bisa menghasilkan keturunan. Praktik sewa rahim sudah mulai banyak di lakukan oleh berbagai negara di Indonesia, meskipun banyak kasus sewa rahim di Indonesia dilakukan secara tertutup. Sewa rahim memunculkan berbagai problematika terutama dalam ranah hukum perdata terkhususnya terkait dengan status hukum anak tersebut, menentukan status hukum anak tersebut merupakan hal yang krusial karena berkaitan juga dengan unsur perdata lainnya seperti hak waris. Adapun yang menjadi permasalahan dalam penelitian ini adalah bagaimana pengaturan hukum sewa Rahim (surrogate mother) dalam perspektif hukum positif Indonesia dan bagaimana hak waris seorang surrogate mother dengan anak hasil sewa rahim. Artikel ini menggunakan metode penelitian yuridis normatif serta pendekatan undang-undang menggunakan Kitab Undang-Undang Hukum Perdata sebagai acuan utama, hasil penelitian menunjukan bahwa anak yang terlahir merupakan anak dengan status anak luar kawin dan yang memiliki hak waris atas anak tersebut adalah ibu pengganti (surrogate mother).
Guía metodológica para la implementación de televisión digital en Bolivia
Authors:   XTOTV Enlace (Bolivia), Mejia Noe Alex Fernando , Arambarri Jon ,   Universidad Europea del Atlántico (España)
Published: October 2022

The migration to Digital Terrestrial Television or Open Digital Television, with the ISDB-Tb standard, is a transition that involves several changes and heavy investments in the transmission and development of content by television companies and also meansa change for users, since they must also adapt their televisions to have access to the new signal with more audio and video quality. It is necesary to study the regulations, to point out the essential requirements for the different phases of implementation, in joint work with companies and specialized professionals, with international recognized good practices in project management. In Bolivia, Telecommunications Law 164 was amended on August 31, 2017 to provide a conglomerate of resolutions and decrees that promote the digital migration of the different analogue television channels and subsequently a series of provisions were established for operating licensing for 15 more years for each current operator, for free. The channels companies have a new digitalblackout period for the 3 main cities until November 2021 and others with less coverage until November 2025. The guide resulting from this work has already been applied and its contribution to all other channels is expected.
TireEye: Optical On-board Tire Wear Detection
Authors: Huber Sebastian , Preindl Peter , Betz Johannes
Published: October 2022

Automotive tire tread depth has a major influence on a car's safety and thus has to be closely monitored. However, there is currently no on-board solution that can measure tire wear with an accuracy of less than 1 mm. TireEye is an optical device mounted inside the wheel well and facing towards the road. It records the cross-section of the longitudinal tread groove and extracts its outline by means of adaptive Canny edge detection. The tread wear indicators serve es means to calibrate the scale since they provide the minimum tread depth.
Remaining useful life estimation of turbofan engines using adaptive fault detection learning
Authors: Soualhi Moncef , Nguyen K , Medjaher Kamal , Zerhouni N
Published: October 2022

Failure prognostics have greatly enhanced the predictive maintenance of industrial systems by providing the remaining useful life (RUL) information, offering opportunities for high reliability, availability, maintainability and safety. To do so, historical monitoring data are injected into machine learning model to learn how to predict the RUL and then, in an online phase directly estimate the RUL of a new similar system. However, in case of multiple degradation trends representing multiple systems, it lead to different times of anomaly appearance and therefore various RUL values for learning. This situation makes difficult to train the predictor and use in this case an approximated unique RUL value. Hence, this paper proposes an adaptive anomaly detection methodology to identify the times of fault occurrence, and then assign the correct RUL values of each failure trajectory to the train the predictor. This methodology will facilitate the learning task for an accurate prediction of system RUL. The performance of the proposed methodology is highlighted using a long short-term memory (LSTM) network with the accelerated run to failure data of turbofan engines provided by the NASA to estimate the RUL.
The effects and side effects of liraglutide as a treatment for obesity
Authors: Ha Jeonghoon , Yu Jin , Lee Joonyub , Kim Hun-Sung
Published: October 2022

The incidence of obesity is increasing throughout the world, including Korea. Liraglutide, the main purpose of which is glucose control, has recently gained significant attention due to its additional effect on weight loss. Liraglutide injections have been widely used as an important treatment for obese patients in Korea. In addition to weight loss, liraglutide has various other effects, such as prevention of cardiovascular disease. Despite its excellent effect on weight loss, notable side effects, such as nausea and vomiting, have also been associated with liraglutide. Despite these side effects, liraglutide has not been discontinued due to its beneficial effects on weight loss. Nonetheless, there are reports wherein patients did not experience weight loss upon taking the drug. As such, there is a possibility of liraglutide misuse and abuse. Therefore, physicians need to have a broad understanding of liraglutide and understand the advantages and disadvantages of liraglutide prescription.
Metabolically healthy obesity: it is time to consider its dynamic changes
Authors: Cho Yun Kyung , Jung Chang Hee
Published: October 2022

Obesity reduces life expectancy, lowers quality of life, and causes numerous cardiometabolic diseases and some cancers. However, the individual risk of developing obesity-associated comorbidities is highly variable and cannot be explained only by body mass index. Observations that some obese people have a low risk for cardiometabolic disorders gave rise to the notion of metabolically healthy obesity (MHO). Despite the lack of a precise definition, MHO is typically identified by normal glucose and lipid metabolism indices, as well as the absence of hypertension. In individuals with MHO, the absence of metabolic abnormalities may minimize the risk of mortality, cardiovascular diseases, chronic kidney disease, dementia, and cancer, compared to metabolically unhealthy individuals with obesity. However, MHO appears to be a temporary phenotype that may not confer permanent benefits to individuals with obesity, further justifying therapeutic efforts to maintain metabolic fitness. In this review, we describe the traits of the MHO phenotype, its changeable nature, and the factors associated with phenotype change. In addition, we discuss the clinical outcomes of the MHO phenotype, particularly focusing on the transition of metabolic health over time and its effect on cardiometabolic disorders. Finally, the clinical importance of maintaining metabolic health is emphasized.
Public awareness of cardiovascular disease prevention in Korea
Authors: Kim Eunji , Jung Chan-Hee , Rhee Eun-Jung , Noh Junghyun , Lee Jae Hyuk , Park Hun-Jun , Park Sungha , Ihm Sang-Hyun , Lee Won-Young , Kim Hyeon Chang
Published: October 2022

Background: The burden of cardiovascular disease (CVD) is significant in Korea. Ultimately, public knowledge and awareness of CVD risk factors and prevention are essential to reduce its burden. Hence, this study aimed to examine the level of public awareness of CVD risk factors and prevention in Korea in 2022. Methods: We used data from the Cardiovascular Disease Prevention Awareness Survey conducted by the Korean Society of Cardiovascular Disease Prevention in June 2022. Using a structured web-based questionnaire, 2,000 individuals aged 20 years or more were surveyed on computers or mobile devices. Information on sociodemographic characteristics, the presence of cardiometabolic disease, CVD concerns and self-assessed likelihood, and awareness of CVD prevention were analyzed. Results: Cancer (44.3%) was the most feared disease, followed by CVD (19.5%). Nevertheless, most respondents stated that they were likely to develop CVD in their lifetime (67.4%). Only 9.2% of respondents were aware of the details of recommendations to prevent CVD, and this level of knowledge was also low among respondents with cardiometabolic diseases (10.7%). Not smoking, being physically active, eating a healthy diet, and reducing alcohol consumption were deemed easy to implement. On the contrary, reducing stress, being physically active, and eating a healthy diet were considered the most difficult recommendations to practice.Conclusions: Public awareness of CVD risk factors and prevention appeared to be insufficient in Korea. Our research suggests that simple but practical recommendations should be conveyed and promoted to raise public awareness, which is currently inadequate.
Reduced Carbon Monoxide Emission in Ghee Lamp than Peanut Oil Lamp
Authors: Shukla Divya , Sursaut Rewati Mitaram , Kumar Mohit
Published: October 2022

Lighting the lamp is an ancient tradition of Indian culture. Various cultures such as Indian, Chinese, Tibetan, Japanese, etc. widely use ghee for religious purposes. In India, Ghee is an essential component of most of the rituals. Ayurveda suggests different types of vegetative oils and ghee (clarified butter) for Ayurvedic preparations. Both ghee and peanut oil are commonly used in food preparations. Besides for eating, both ghee and peanut oil lamps are also commonly used for lighting lamps in India. Hence, evaluating the emissions from these lamps is of interest. In the present comparative study we have evaluated the emission of air pollutants: Particular Matter (PM1, PM2.5, PM10), Sulphur Dioxide (SO2), Nitrogen Dioxide (NO2), Ozone, Carbon Monoxide (CO), and Carbon Dioxide (CO2) from peanut oil and ghee lamps. We found that there was no significant difference between oil and ghee lamps for all emissions except for CO, where there was a significant reduction (15.93%, p= 0.0183) in ghee lamps compared to peanut oil lamps. Lower CO from ghee lamps than that from peanut oil lamps might be due to differences in the combustion efficiency resulting from chemical structure differences. Thus, the present finding of reduced CO emission from ghee lamps supports its wide use as a component in Indian religious purposes, Vedic-rituals of Yagya or Havan and meals.
Pengaruh Platform Wordwall Berbasis Website dalam Meningkatkan Minat Belajar Peserta Didik pada Mata Pelajaran PAI
Authors: Maghfirah Syahidatil , Sulaiman Sulaiman
Published: October 2022

This study aims to determine the effect of a website-based wordwall platform on students' interest in learning. The type of this research is quantitative with a pre-experimental method of design one shoot case study. The subjects of this study were students of class X TJKT SMK Negeri 2 Padang. The data collection instrument used was a questionnaire with additional supporting data such as observations, interviews and documentation. The results showed that 1) from the results of hypothesis testing using the t test, it was stated that t table > t arithmetic, namely 5.666 > 2.03951, with a significance value of 0.000 which means <0.05 this means that H1 is accepted and H0 is rejected. 2) based on the results of the f test, the results of f table > f count are 32.106 > 4.16, which means that the wordwall platform variable (x) has an influence on increasing the learning interest variable (y). 3) from the simple linear regression test the equation Y = 17,830 - 1,225X
O pai e a função paterna na teoria winnicottiana
Authors: Santos Gabriel Aparecido Gonçalves dos , Barbieri Valeria , Santos Manoel Antônio dos
Published: October 2022

A teoria psicanalítica de D. W. Winnicott assume a existência de uma tendência inata ao desenvolvimento que depende, para ter êxito, do oferecimento suficientemente bom de recursos ambientais que deem suporte e estimulem o desenvolvimento e integração do Self em formação. Grande parte de sua obra enfoca o papel da mãe como principal agente fornecedor de cuidados ao recém-nascido. Contudo, Winnicott não deixou de abordar a importância do pai como elemento real da dinâmica familiar e, como tal, também agente de cuidados do filho e da díade mãe-filho, pois o consi-dera como parte do ambiente total disponível da criança. Esse artigo busca descrever e analisar as principais proposições teóricas do autor e de estudiosos contemporâ-neos a respeito do pai e das funções paternas na família, de acordo com cada etapa do amadurecimento pessoal em que o filho se encontra.
A experiência de acompanhamento de bebês em escolas de educação infantil através da Metodologia IRDI
Authors: Silva Milena da Rosa , Ferrari Andrea Gabriela
Published: October 2022

Este trabalho relata uma pesquisa-intervenção, sustentada na psicanálise, em berçá- rios de escolas de educação infantil. Utilizou-se a Metodologia IRDI como dispositivo de leitura da constituição psíquica do bebê e da relação educadora-bebê. Sobre a constituição psíquica dos bebês, foi possível intervir a tempo com aqueles que apre- sentavam sinais iniciais de sofrimento psíquico. Quanto às educadoras, ao final do acompanhamento, elas demonstraram estar questionando-se mais quanto ao seu trabalho e mais conectadas com as necessidades afetivas dos bebês. As coordenações/direções das escolas puderam repensar algumas rotinas a partir das necessi- dades que os bebês apresentavam. Foi possível pensar nos recursos da Metodologia IRDI como dispositivo de acompanhamento dos bebês em berçário e de cuidado de quem cuida, como suporte às educadoras.
Arecanut Segregation System Using Local Binary Pattern and HOG Features
Authors: Mulla Asif Iqbal , Sab Ayaz , Gubbi Abdullah
Published: October 2022

Agriculture is, doubtlessly, one of the most relevant fields that drive Indian economy. India produces diverse types of spices and seeds depending upon the different soil and climate conditions. India is also one among the cultivator of arecanut and much of its production happens in the coastal region. It is a tropical crop. There is a variation in the quality of arecanut that makes it classified into various types. The arecanut classification and segregation is necessary, basically segregation is done manually which consumes much time, more effort and more error prone. This paper proposes an automatized approach of classification and segregation using hardware and digital image processing
PLASMA TECHNOLOGY FOR THE PRODUCTION OF GLASS MICROBEADS BASED ON THE BREAKAGE OF CONTAINER AND GRADED GLASSES
Authors:   V.G. Shukhov Belgorod State Technological University, Bessmertnyi Vasily S. , Minko Nina I. ,   V.G. Shukhov Belgorod State Technological University, Bondarenko Marina A. ,   V.G. Shukhov Belgorod State Technological University, Kochurin Dmitry V. ,   V.G. Shukhov Belgorod State Technological University
Published: October 2022

A technology – based on the breakage of graded and container glasses – was developed for the production of glass microbeads in a plasma reactor. The regularities of the influence of the flow rate of plasma-forming gas argon and the power of the plasma reactor on the fractional composition of glass microbeads were established. It was shown that with an increase in the flow rate of plasma-forming gas from 1.0 m3/hour to 2,0 m3/hour and the current strength from 300 A to 400 A, the amount of fraction over 630 microns increases due to coagulation processes. It was established that under the influence of high plasma temperatures, about 6000-8000 K, complete melting and sphering of particles occur with the formation of glass microbeads ranging in size from 80 microns to 1250 microns. The microhardness, acid resistance and alkali resistance of glass microbeads were investigated.
ARLAN FIBER IS AN ADVANCED RAW MATERIAL FOR THE PRODUCTION OF FIRE-RESISTANT MATERIALS
Authors:   Representative Office in Russia TEXTIMA EXPORT IMPORT GmbH, Bakhteeva Ksenia Yu. , Musina Tamara K. ,   Lirsot LLC, Diankova Tamara Yu. ,   St. Petersburg State University of Industrial Technologies and Design
Published: October 2022

The article provides a comparative analysis of the functional properties of meta-aramide fibers of Russian and foreign manufacturers. The possibilities and limitations of the use of materials based on Arlan fiber are shown. A high level of fire protection of LIRSOT LLC products in combination with hygroscopicity was noted.
Jugendliche und junge Erwachsene im urbanen Umfeld als Fokus der Kriminalprävention - 13. Zürcher Präventionsforum – Tagungsband 2022
Authors: Baier Dirk , Hestermann Thomas , Holderegger Nicole , Schaffer Bernadette , Schneider Martina , Walser Simone , Wirz Michael , Zimmerlin Sven
Published: October 2022

Gemäss polizeilicher Kriminalstatistik steigt die Jugendkriminalität seit fünf Jahren wieder an. Insbesondere Gewaltdelikte haben stark zugenommen. Dieser Trend manifestiert sich nicht nur in Zürich, sondern auch in anderen Städten. Stimmt die Realität mit der Kriminalitätsstatistik überein und welches sind mögliche Gründe für diesen Anstieg? Ist er eine Folge des Bevölkerungswachstums oder sind neue Formen des Freizeitverhaltens sowie gewaltlegitimierende Einstellungen der Jugendlichen ausschlaggebend? Wie kann dieser Entwicklung mit kriminalpräventiven Mitteln begegnet werden? Diese Fragen soll die Tagung aus kriminologischer und präventiver Sicht beleuchten. Es referierten PräventionsexpertInnen aus den Bereichen Polizei, Jugendstrafverfolgung, Sicherheit und Forschung über Ursachen und wirksame Präventionsmassnahmen. Diese aktuellen Fragen wurden im Rahmen des 13. Zürcher Präventionsforums aus kriminologischer und präventiver Sicht beleuchtet.
Formulation and Evaluation of Zolmitriptan Loaded Nano-Structured Lipid Carriers for Effective Treatment in Migraine
Authors: Prajapati Dr. Bhupendra , Varia Umang , Patel Aara
Published: October 2022

Objective: Zolmitriptan is a BCS class II drug having low solubility and poor bioavailability by formulating Nanostructured lipid carriers that will sustain the release of the drug for a longer period which leads to reduced dose and frequency of dose.
Method: Zolmiptriptan-loaded Nanostructured lipid carriers were fabricated by a solvent diffusion evaporation method. The formulation parameters like the selection of solid (Precirol ATO 5) and liquid lipid (Miglyol 812), solid to liquid lipid ratio (3:1), drug: solid lipid ratio (1:4), the ratio of the organic phase (Acetone: Ethanol, 1:1), the concentration of surfactant (1.5% Tween 80) and temperature               (70 °C) of secondary phase were optimized. NLC dispersion was finally lyophilized and converted into a tablet. A stability study of freeze-dried NLCs tablet was performed according to ICH Q1A (R2) guidelines.
Result: Optimized formulation contained Particle size 11.39 ± 0.85 nm, Zeta potential -38.30 and %EE 76.56 ± 0.12. Characterization was performed by TEM and FTIR analysis. The residual solvent test confirms the concentration of organic solvents was in the acceptable range as per ICH guidelines. In-vitro drug permeation study of NLCs shows 88.91±0.238 % drug release while pure drug suspension shows 58.9±0.578 % drug release after 12 hrs. 
Conclusion: Zolmitriptan-loaded NLCs show better absorption as compared to pure drug suspension which indicates prolonged release of medicament which may reduce dose or dose frequency.
Clinical utility of liquid biopsy-based companion diagnostics in the non-small-cell lung cancer treatment
Authors: Sato Yoshiharu
Published: October 2022

Recently, technological advances in the detection and biological characterization of circulating tumor DNA (ctDNA) have enabled the implementation of liquid biopsy testing into clinical practice. Methods for analysis of liquid biopsies have rapidly evolved over the past few years and have continued to advance, thus providing details about tumor biological characteristics such as tumor progression, metastasis, tumor heterogeneity, genomic mutation profile, clonal evolution, etc. In tandem with technological advances, the implementation of liquid biopsy in routine clinical settings has proceeded. In 2016, the Food and Drug Administration (FDA) approved the first ctDNA liquid biopsy test to detect epidermal growth factor receptor (EGFR) gene mutations in patients with non-small-cell lung cancer (NSCLC) as a companion diagnostic for molecular targeted drug of EGFR-tyrosine kinase inhibitor (TKI, EGFR-TKI). More recently, multigene panel assays of liquid biopsy have been approved as companion diagnostics and have been used in routine clinical settings. The estimation of blood tumor mutation burden (bTMB) to predict the efficacy of immune checkpoint inhibitor (ICI) treatment can be one of the promising approaches to liquid biopsy. The next stage of implementation of liquid biopsy for routine clinical settings is for monitoring of ctDNA after surgical treatment to predict prognosis and to detect disease relapse earlier than conventional imaging diagnosis. Its clinical utility is under assessment in several clinical trials. This review introduces recent advances in liquid biopsy methodology, the development of biomarkers, and its clinical utility in the treatment of NSCLC patients.
Application of Hydrothermal and Solvothermal Method in Synthesis of MoS2
Authors: Huang He , Liu Na , Wang Xueying , Zhong Mei , Huang Xueli
Published: October 2022

Hydrothermal and solvothermal method were considered as the effective methods for preparation of MoS2 nanomaterials. The current researches of MoS2 mainly concerned on electrical properties, the research of reaction system was relatively less. In this paper, synthesis system of MoS2 was elaborated from precursor, solution, reductant, sulfurizing agent, additive and pH regulator. The application of multifunctional raw materials can greatly simplify reaction system. This provided a reference for the application of hydrothermal and solvothermal method in preparation of MoS2.
Penentuan Jalur Distribusi Gas LPG dengan Metode Savings Matrix dan Nearest Neighbor pada PT. XYZ
Authors: Emaputra Andrean , Maulana Kevin Akbar
Published: October 2022

Distribusi merupakan suatu cara perusahaan agar dapat melakukan proses pengiriman dengan tepat. Oleh karena ini pengembangan sistem distribusi sangat dibutuhkan untuk pengembangan bagi perusahaan. PT. XYZ merupakan perusahaan yang bergerak dibidang pendistribusian Gas LPG dari gudang ke pelanggan yang berada di wilayah kabupaten Bantul Daerah Istimewa Yogyakarta. Permasalahan yang terjadi pada perusahaan PT. XYZ sendiri yaitu penentuan dalam rute distribusi yang belum berjalan baik, dikarenakan jarak pangkalan yang cukup jauh menyebabkan tingginya biaya distribusi. Untuk mengatasi masalah pada PT. XYZ, maka diperlukan penerapan metode Savings Matrix dan metode Nearest Neighbor yang digunakan untuk menentukan jalur dan jarak dari gudang ke pangkalan berdasarkan kapasitas alat angkut serta melakukan proses penghematan biaya distribusi untuk penekanan biaya. Tujuan dari penelitian kali ini untuk mendapatkan jalur atau rute distribusi yang tepat dan mendapatkan penghematan biaya distribusi dengan membandingkan setelah dilakukan perbaikan pada PT. XYZ. Dari hasil perhitungan dan analisis yang diperoleh setelah dilakukan perbaikan menunjukan bahwa jarak  tempuh sejauh 4.945 kilometer dengan biaya distribusi Rp22.525.500. Penghematan jarak yang dihasilkan setelah dilakukan perbaikan adalah 24% atau 1.540 Kilometer, sedangkan penghematan biaya distribusi yang dihasilkan adalah 6% atau Rp1.315.950,-/bulan.
Evaluasi Penjadwalan Proyek Kapal Penyeberangan RO-RO 500 GT Melalui Pendekatan Metode CPM Dan PERT Studi Kasus PT. XYZ
Authors: Ahmad Padhil  , Muhammad Shadiq Anwari  , Abdul Mail  , A. Dwi Wahyuni P  , Muhammad Fachry Hafid
Published: October 2022

PT. XYZ yang merupakan galangan yang memiliki peluang yang besar untuk menjadi galangan maju ini didukung oleh tenaga tenaga Engineering yang berkualitas dan professional dan ketersedian material yang memadai. Tujuan dari penelitian ini adalah untuk melakukan evaluasi penjadwalan proyek kapal penyeberangan Ro-Ro 500 GT dan menentukan waktu optimal dalam menyelesaikan sebuah proyek kapal Penyeberangan Ro-Ro 500 GT. Penelitian ini menggunakan metode CPM (Critical Path Method), PERT (Program Evaluation and Review Technique). Hasil evaluasi penjadwalan di PT. XYZ dengan menggunakan metode CPM pada analisa dan pengolahan data dengan membandingkan waktu pada time schedule perusahaan selama 36 minggu, 252 hari dengan hasil analisis dengan menggunakan metode CPM didapatkan waktu pengerjaan selama 42 minggu, 292 hari. maka dapat disimpulkan bahwa dengan menggunakan metode CPM dapat menyelesaikan proyek dengan tepat waktu sesuai waktu realisasinya dibandingkan dengan menggunakan metode time schedule perusahaan dengan selisih pengerjaan nya sebanyak 6 minggu. Sedangkan dengan menggunakan metode PERT didapatkan hasil pengerjaan dengan waktu optimal selama 43 minggu.
A systematic review of the empirical literature on character development in individuals in low- and middle-income countries
Authors:   Oxford Policy Management, Jeffery-Schwikkard David , Lomas Timothy , Nagpal Phalasha , Morgan Ellen , Li Junying
Published: October 2022

Review question / Objective: How has character development in individuals been studied in low-income and middle-income countries? Constituent questions: 1. Which populations are being studied? a. Which demographics? (gender, age, income, minorities, disabilities) 2. What aspects of character development are being studied? a. Including for interventions – intervention design, duration, dosage. b. How is character development itself conceptualized and operationalized? 3. What are the contexts of these studies? a. Which countries? b. For interventions – what is the site of the intervention? (e.g., schools, communities, religious institutions) 4. What are the methodological designs of these studies? a. What measurement tools are used in these studies? i. Are these developed for use (or otherwise adapted for use) in these regions? If so, how? b. What is the quality of these studies? 5. What are the key findings of these studies? 6. Who is funding and conducting this research?
Tuina for osteoarthritis : a protocol for systematic review
Authors:   Affiliated Hospital of the Changchun University of Chinese Medicine, Weidong Zhang , Cui Zhenhai , Sha Liquan , Zhao wenhai
Published: October 2022

Review question / Objective: As a traditional Chinese medicine technique, massage can treat osteoarthritis. The aim of this systematic review protocol was to evaluate the value of the efficacy and safety of tuina in the treatment of osteoarthritis. Condition being studied: Osteoarthritis (OA) is a particularly common chronic degenerative disease that not only severely affects patients' joint function and quality of life, but also causes serious health problems worldwide. Tuina, a traditional Chinese medicine technique, has been widely used to treat OA in Asian countries such as China and Thailand, but the evidence for its effectiveness is unclear.
INFLUÊNCIA DA CULTURA NO BEM-ESTAR MATERNO-FETAL: UMA REVISÃO NARRATIVA
Authors: Lopes Joana Nunes Dias , Pereira Sara Cristina Gaitas Rodrigues , Frias Ana Maria Aguiar , Barros Maria da Luz Ferreira
Published: October 2022

Na Gravidez a família é preponderante para o seu sucesso, pois é esta que transmite as suas crenças e costumes, de acordo com a sua cultura, que idealmente proporcionará um parto seguro, com mãe e recém-nascido saudáveis. Com esta revisão narrativa pretendemos conhecer os aspetos culturais que influenciam o comportamento das grávidas. Os artigos foram encontrados nas bases de dados PubMed, CINAHL, MEDLINE, MedicLatina, Nursing & Allied Health Collection, Web of Science e Scielo, através de descritores MeSH, entre 2016 e 2021, que abordassem a influencia dos fatores culturais no comportamento das grávidas. De acordo com a literatura analisada, os aspetos culturais centram-se maioritariamente na alimentação e na espiritualidade, tendendo a culpabilizar a mulher em todas as suas práticas enquanto grávida. Assim, os profissionais de saúde devem estar preparados para as possíveis dificuldades encontradas, devendo estar livres de tabus e preconceitos, para que consigam ajudar as mulheres na sua interação entre a sua cultura e o mundo hospitalar ocidental.