bluuebunny/crossref_metadata_2025 huggingface dataset:
Synthesis Of 5, 7-Diaryl-1,5-Dihydro (Or 1, 2, 3, 5-Tetrahydro)- Pyrano[2, 3-D] Pyrimidin-2, 4-Diones (Or 2-Thioxo-4-Ones).
Authors: Ullah Mohammad Shahid , Ahmed M Giasuddin , Romman UKR , Akhter Kawsari , Ahmed S Mosaddeq , Halim Md. Ershad
Published: May 2013

Some 5, 7-diaryl-1,5-dihydro (or 1, 2, 3, 5-tetrahydro)- pyrano[2, 3-d] pyrimidin-2, 4- diones (or 2-thioxo-4-ones) (3a-g) has been synthesized in one-step by the cyclocondensation of barbituric acid or thiobarbituric acid (1) with arylideneacetophenones (2a-d), in glacial acetic acid in the presence of phosphorous pentoxide. The structures of the compounds 3a-g were determined by their UV, IR, 1H NMR, 13C NMR, mass spectral data and elemental analyses. Journal of Bangladesh Chemical Society, Vol. 25(2), 124-131, 2012 DOI: http://dx.doi.org/10.3329/jbcs.v25i2.15064
Synthesis And Characterization Of Mixed Ligand Complexes Of Co(Ii) And Fe(Iii) Ions With Maleic Acid And Heterocyclic Amines
Authors: Hossain Md. Belayet , Islam M Saidul , Islam M Rafiqul , Salam Md. Abdus , Yousuf M. Abu
Published: May 2013

This paper describes the preparation and characterization of mixed ligand complexes of Co(II) and Fe(III) ions with maleic acid and heterocyclic amines of general formula [M(ME)L] and K[M(ME)L] (where M = Co(II) (1-4), Fe(III) (5-6); ME = C4H2O4 (1-4), 2C4H2O4 (5-6); L = C5H6N2 (1), C9H7N (2-3), C9H6NO (4), C5H5N.H2O (5), C6H7N (6)). The molecular structures of the complexes have been determined by spectral, magnetic studies and elemental analysis. Journal of Bangladesh Chemical Society, Vol. 25(2), 139-145, 2012 DOI: http://dx.doi.org/10.3329/jbcs.v25i2.15066
Solvatochromic And Fluorescence Spectroscopic Studies On Polarity Of Ionic Liquid And Ionic Liquid-Based Binary Systems
Authors: Ahmed Kumkum , Auni Anika , Ara Gulshan , Rahman MM , Mollah M Yousuf Aa , Susan Md. Abu Bin Hasan
Published: May 2013

Polarity behavior of a hydrophobic ionic liquid (IL) 1-ethyl-3-methylimidazolium bis(trifluoromethyl)sulphonylimide [EMI][TFSI] and binary mixtures of [EMI][TFSI] with ethanol, acetone and dichloromethane was investigated by solvatochromic method using Reichardts betaine dye. Fluorescence spectroscopic method using pyrene as a probe was also used for estimation of polarity of [EMI][TFSI] and [EMI][TFSI]-based binary systems. The binary mixtures of [EMI][TFSI] with the molecular solvents interestingly showed increase in polarity with increasing [EMI][TFSI] for all compositions. The comparative and contrastive features of the results of two methods have been discussed to judge relative merit of one method over the other. Both of the methods collectively provided information to correlate specific interaction of the IL with molecular solvents and define polarity behavior. Journal of Bangladesh Chemical Society, Vol. 25(2), 146-158, 2012 DOI: http://dx.doi.org/10.3329/jbcs.v25i2.15067
Impact Of Heavy Metals On Water And Soil Environment Of A Paint Industry
Authors: Jolly YN , Hossain A , Sattar A , Islam A
Published: May 2013

A study on the heavy metal impact of a paint industry effluent on the surrounding water and soil environment was carried out. This investigation included a variety of sample types essentially related to the impact assessment. The effluent samples collected from Berger Paints Bangladesh Ltd., Savar, were found to contain K, Ca, Mn, Fe, Zn and Sr with the mean concentrations of 9.78, 221, 0.027, 0.031, 0.067 and 0.29 mg L-1, and values of pH, EC, TDS, TSS, BOD and COD measured in those samples were 5.8, 1.28 mS cm-1, 1084 mgL-1, 66 mg L-1 and 101 mg L-1, respectively. The mean concentrations of K, Ca, Mn, Fe, Zn and Sr in groundwater samples and the values of pH, EC, TDS, TSS found in those samples were 1.58, 16.27, 0.25, 0.013, 0.058 and 0.14 mg L-1 and 7.2, 0.17 mS cm-1, 145 mg L-1, and 10 mg L-1, respectively. The effluent receiving pond water showed the presence of K, Ca, Fe, Zn, Br, and Sr with the average concentrations of 3.37, 23, 0.32, 0.37, 0.03 and 0.11 mg L-1, respectively. The respective concentrations of elements-K, Ca, Mn, Fe, Cu, Zn, Br, Rb and Sr detected in aquatic plant (Halenchi shak) growing on effluent receiving pond water were 46400, 4846, 148, 174, 12.7, 62, 37, 124 and 23 mg kg-1. The mean contents of K, Ca, Ti, Mn, Fe, Cu, Zn, Rb and Sr in samples of paint industry-adjacent agricultural land soil were 10128, 8131,5260, 642, 24025, 56, 84, 135 and 138 mg kg-1, respectively. The mean concentrations of elements in pond water (K: 2.49, Ca: 15.2, Fe:0.19, Zn: 0.24, Br: 0.03 and Sr: 0.11 mgL-1), Halenchi shak (K: 42259, Ca: <1837, Mn: <58, Fe: 163, Cu: <14, Zn: 47, Br: 20, Rb: 68 and Sr: 16 mg kg-1) and soil samples (K: <5491, Ca: <3300, Ti: 5034, Mn: 514, Fe: 34660, Cu: 58, Zn: 65, Rb: 135 and Sr: 38 mg kg-1) collected from a pollution free non-industrial zone indicated lower levels for the same parameters than those in corresponding above mentioned effluent-polluted samples. Journal of Bangladesh Chemical Society, Vol. 25(2), 159-165, 2012 DOI: http://dx.doi.org/10.3329/jbcs.v25i2.15068
Method Development And Validation For Estimation Of Commercially Produced Sex Pheromones In Lure
Authors: Mandal Shankar , Rahman AMH , Mamun MIR , Shoeb Mohammad , Nahar Nilufar
Published: May 2013

A method was developed and validated for quantitation of methyl eugenol and cuelure, the active ingredients of two formulated sex pheromones (bio-pesticides) Mukti and Jhilik by gas chromatography. Technical grade methyl eugenol and cuelure (purity 95- 96%) were used as standards. Calibration curves of methyl eugenol and cuelure were linear with correlation coefficient (r2) 0.9966 & 0.9988, respectively. Ten replicate analyses were done for both methyl eugenol & cuelure and quantity of the pheromones in the two formulated products were found to be 0.55 ± 0.11 and 0.56 ± 0.09 g/lure (Mean ± SD), respectively. The stability of both pheromones in solution and their diffusion from lures under UV-Vis light was determined for a period of 21 days. The results showed that diffusion of the both pheromones from lure were very fast and about two-third diffused within 10 days after exposure. Methyl eugenol was quite stable in solution, whereas cuelure was found to degrade slowly, and about 15 % cuelure degraded within 21 days. The recovery of methyl eugenol and cuelure from matrix were found to be 80.69 ± 3.14 and 78.48 ± 4.32 % (mean ± SD), respectively, where limit of detection (LOD) & limit of quantification (LOQ) were found to be 97 & 80 ppm, and 290 & 240 ppm, respectively. The developed method is very simple and can be used for estimation of the two sex pheromones. Journal of Bangladesh Chemical Society, Vol. 25(2), 180-185, 2012 DOI: http://dx.doi.org/10.3329/jbcs.v25i2.15084
Synthesis Of 2-Benzoyl-3,4,5,6-Tetrasubstitutedbenzoic Acid From Tetrasubstituted Phthalic Anhydride Using Organometalics
Authors: Biswas Pizush Kanti , Huq Enamul , Rahman MT , Nur Husna Parvin
Published: May 2013

The reactions of phenylcoppermagnesium and phenylmagnesium bromide reagents with perchlorophthalic anhydride were investigated. Along with 2-benzoyl-3,4,5,6- tetrachlorobenzoic acid, five other substituted products were isolated and their structure were determined by detailed spectroscopic studies. Journal of Bangladesh Chemical Society, Vol. 25(2), 186-193, 2012 DOI: http://dx.doi.org/10.3329/jbcs.v25i2.15085
Self-Assemble Monolayer Dependent Field Effect Transistors Performance Based On Tetracene Single-Crystal
Authors: Islam Md. Minarul
Published: May 2013

Organic field effect transistors with an active layer based on the tetracene single-crystal were fabricated. It was found that organosilane self-assemble monolayer (SAM) modified device with tetracene single-crystals gave higher mobility and on/off ratio rather than untreated device. SAM modified tetracene single-crystal transistors with parylene gate insulator showed the highest mobility of 0.66 cm2 V-1 s-1 and high on/off ratio of ~104. This finding demonstrates that SAM treatment decrease the charge leakage between source and drain which help to decrease the off current with greater extent and increase the on current slightly of the tetracene single-crystal field-effect transistors. Journal of Bangladesh Chemical Society, Vol. 25(2), 194-199, 2012 DOI: http://dx.doi.org/10.3329/jbcs.v25i2.15086
Studies Of Dissipation Pattern Of Cypermethrin In Tomato
Authors: Nahar Nilfur , Shoeb Mohammad , Mamun M Iqbal Rouf , Ahmed Sultan , Hasan Mir Mahadi , Kabir Ahmedul
Published: May 2013

Dissipation pattern of cypermethrin (Ripcord 10EC) on tomato plants sprayed at recommended and double the recommended doses followed first order kinetics. In both the doses residues were found below the maximum residue level (0.5 ppm) after one day of application. Recoveries were found to be 80.88% &77.09% spiked at 0.2 & 0.5 ppm, respectively. LOD and LOQ were found to be 0.01 and 0.06 ppm, respectively. Journal of Bangladesh Chemical Society, Vol. 25(2), 200-203, 2012 DOI: http://dx.doi.org/10.3329/jbcs.v25i2.15087
Anthrax Diseases
Authors: Ali Md. Zulfikar
Published: May 2013

DOI: http://dx.doi.org/10.3329/kyamcj.v1i1.13297KYAMC Journal Vol.1(1) July 2010, 1-2
Experience with P. Falciparum Malaria in a tertiary care hospital in Bangladesh
Authors: Rahman M Monzur , Ali M Zulfikar , Akhteruzzaman M
Published: May 2013

DOI: http://dx.doi.org/10.3329/kyamcj.v1i1.13298KYAMC Journal Vol.1(1) July 2010, 1-2
Reasons in favour of home delivery among mothers in rural community
Authors: Hussain Rubayet Farzana , Rahman Md. Mahfuzar
Published: May 2013

DOI: http://dx.doi.org/10.3329/kyamcj.v1i1.13299KYAMC Journal Vol.1(1) July 2010, 8-15
Abdominal Tuberculosis
Authors: Rabbi ANM Atai , Jahan Ferdous Ara J. , Aziz M Mohibul
Published: May 2013

DOI: http://dx.doi.org/10.3329/kyamcj.v1i1.13300KYAMC Journal Vol.1(1) July 2010, 16-20
Non-modifiable Risk Factors and Coronary Angiographic finding - Study in a tertiary rural Centre of Bangladesh
Authors: Islam Md. Saiful , Talukder Ranjan , Moniruzzaman Md.
Published: May 2013

DOI: http://dx.doi.org/10.3329/kyamcj.v1i1.13301KYAMC Journal Vol.1(1) July 2010, 21-23
Uroflowmetry in bladder outflow obstruction evaluating sensitivity and specificity - A clinical study
Authors: Mallik Ashraf Uddin
Published: May 2013

DOI: http://dx.doi.org/10.3329/kyamcj.v1i1.13303KYAMC Journal Vol.1(1) July 2010, 24-26
Early Detection of Atherosclerotic Changes in Diabetic Patients
Authors: Dey Prashanta Prasum , Paul S
Published: May 2013

DOI: http://dx.doi.org/10.3329/kyamcj.v1i1.13304KYAMC Journal Vol.1(1) July 2010, 27-29
Analgesic Nephropathy and Hyperparathyroidism - a case report
Authors: Ahmed Sheikh Salahuddin , Ali Md. Zulfikar , Laila Tarafdar Runa
Published: May 2013

DOI: http://dx.doi.org/10.3329/kyamcj.v1i1.13305KYAMC Journal Vol.1(1) July 2010, 30-33
CMC with Pregnancy - A case report
Authors: Rahman MM , Jalaluddin SM , Hossian L , Amran A , Kalam A , Ahsan S , Islam S , Begum S
Published: May 2013

DOI: http://dx.doi.org/10.3329/kyamcj.v1i1.13306KYAMC Journal Vol.1(1) July 2010, 34-35
Nipah virus - Reemergence in Bangladesh
Authors: Ali Md. Zulfikar
Published: May 2013

DOI: http://dx.doi.org/10.3329/kyamcj.v1i2.13311KYAMC Journal Vol.1(2) January 2011, 36-38
Study of relation between Body Mass Index (BMI) and Angiographically severity of Coronary Artery Disease
Authors: Islam Md. Saiful , Talukder Ranjan , Sakib Annaz Mus , Mokhlesuzzaman AKM
Published: May 2013

Background: Increased body mass index (BMI) is known to be related to ischaemic heart disease (IHD) in populations where many are overweight (BMI ? 25 kg/m2) or obese (BMI ? 30). Substantial uncertainty remains, however, about the relationship between BMI and severity of Coronary artery disease. Methods and Results: Total 152 patients undergoing coronary angiography for clinical indication (eg; stable angina, unstable angina, STEMI, NSTEMI). Among them 88.15% male and 11.84% female.6.57% were under weight, 69.07% were normal weight, 20.39% were over weight and 3.94% were obese or morbid obese. Normal & minimal coronary artery disease more common in under weight & normal weight patient ( 60% in underweight patient, 21.88% in normal weight patient compare to 16.12% in over weight & obese person). Tripple Vessel disease are more common in over weight and obese person (45.16% in over weight and 50% in obese person compare to 10% in under weight and 33.33% in nonmal weight person). Conclusion: In patients with established Ischemic heart disease, Increase BMI was associated with increase number of coronary lesion ( doable and tripple vessel disease more common in over weight and obese person). DOI: http://dx.doi.org/10.3329/kyamcj.v1i2.13312KYAMC Journal Vol.1(2) 2011 pp.39-42
Detection of Impurities in a tablet of Atorvastatin
Authors: Misbahuddin Mir , Islam Md. Saiful , Sarker Uttam Kumar
Published: May 2013

Identification of impurities and their amounts in the atorvastatin bulk drug and tablet DIVASTINTM (20 mg) were done using HPLC with diode array detector. The composition of mobile phase was acetonitril:phosphate buffer (45:55%; pH 4.0) with flow rate of 0.5 mL/min and detected at 248 ± 8 nm. Four impurities (desfluoro atorvastatin, distereoisomer, 3-o-methyl atorvastatin and lactone atorvastatin) were detected in the bulk drug whereas five impurities were detected in the tablet DIVASTINTM (20 mg). The total amounts of impurities in atorvastatin bulk drug and tablet were 0.804 and 0.983% respectively. In conclusion, the total amount of impurities was less than 1% which is acceptable.DOI: http://dx.doi.org/10.3329/kyamcj.v1i2.13313KYAMC Journal Vol.1(2) January 2011, 43-47
A study to see effects of radiation alone and radiation with concurrent chemotherapy for advanced squamous cell carcinoma of head and neck
Authors: Bhattacharjee Biswajit , Sengupta AShim Kr. , Bari MA , Hai MA
Published: May 2013

Aim: To observe the responses of radiation with concurrent chemo-radiation and radiation alone at the primary tumour sites and metastatic neck nodes of patients with head and neck cancers weekly during treatment, after completion of treatment and at 6 weeks interval after treatment.Methods: Randomizes prospective study was carried out in the Department of Radiotherapy, Dhaka Medical College and Hospital, Dhaka during the period of July 2003 to June 2004. Patients with histologic and/or cytologic confirmation of the diagnosis of squamous cell carcinoma of head and neck without distance metastasis were included in this study. After proper evaluation Arm-A was treated by concurrent chemotherapy with Inj. Cisplatinum 75mg/m2 on Day-1, Day-21 and Day-42 and conventional radiotherapy with a total dose of 60 Gy in 30 fractions in 6 weeks. Arm-B was treated by conventional radiotherapy with the same dose as that of Arm-A. Every patient was evaluated by monitoring routinely to see the responses. All the resultant informations were kept preserved on a prescribed data sheet. These informations were than analyzed statistically and results were compiled accordingly.Result: Out of 28 patients in Arm-A, complete desirable response was observed in 19 cases and partial response in 9 cases, where as out of 30 patients in Arm-B it was 7 and 23 cases respectively.Conclusion: Concurrent chemo-radiation showed better response than radiation alone, though toxicities were little bit higher but it was acceptable and easily manageable.DOI: http://dx.doi.org/10.3329/kyamcj.v1i2.13315KYAMC Journal Vol.1(2) January 2011, 54-58
Topical Clindamycin in the Treatment of Acne Vulgaris
Authors: Sultana Shahnaj , Siddiqul Md. Nure Alom , Rahman Md. Moksedur , Siddiqul Muhammad Afsar , Amin Abdullah Al
Published: May 2013

This study was conducted to evaluate the efficacy, safety and adverse effects of topical clindamycin phosphate 1% lotion in treating acne vulgaris in a group of Bangladeshi people. This prospective study was undertaken in skin & VD out patient department of Rajshahi Medical college Hospital, Rajshahi. A total of 30 patients, 15 (50%) males and 15 (50%) females between ages 15 and 35 years (mean 18 years) with acne of grades I, II and III of duration <3 years to 10 years (mean 3.33 years) were studied. Clindamycin phosphate 1% lotion was administered twice daily for 12 weeks to each patient. Response was excellent in 73.33%, good in 20%, fair in 3.33% and poor in 3.33% of cases. Clinical adverse effects were noted in 20% of cases where oiliness was in 6.67%, irritation and burning in 3.33%, puritans in 3.33%, erythema i3.33% and peeling in 3.33% of cases. None of the reactions was severe, all were mild and well tolerated and most occurred within the first month of initiation of treatment and resolved with continued use of drug and completely cured after the treatment completed. No body had to discontinue the therapy for side effects. 80% of the total patients had no side effects. This study confirms that clindamycin is safe and effective topical therapy for mild to moderate acne vulgaris.DOI: http://dx.doi.org/10.3329/kyamcj.v1i2.13316KYAMC Journal Vol.1(2) January 2011, 59-64
Tubularised incised plate hypospadias repair: a multicellular experience
Authors: Shahid Shah Md. Ahsan , Rahman Md. Mostafizur
Published: May 2013

Objectives: To report the outcomes in a series using modified tubularized incised plate (TIP) urethroplasty (Snodgrass) technique. The use of the TIP urethroplasty (Snodgrass) technique has gained wide acceptance among pediatric urologists for the correction of hypospadias repair because of its good cosmesis, low complication rate, and reliability in creating a vertically oriented meatus. Methods: A total of 54 boys aged 2 -13 years admitted in paediatric surgery ward Glanular(5.5%),Coronal(18.5%),Subcoronal(35.18%), Distal RMCH and IBH,Rajshahi with penile(11.1%),midpenile(9.6%) hypospadias underwent one-stage repair using a modified TIP repair during January,2010 to December,2010 were included in the study. Outcome was reviewed for each patient to determine the complications, reoperations, cosmesis, and functional results after surgery. Results: With at least 6 months of follow-up, all patients had achieved excellent functional and cosmetic results, with the meatus at the tip of the penis on follow-up. Three repairs for meatal stenosis and two for fistula were needed. Conclusions: The modified TIP procedure is a safe and reliable technique. It provides excellent cosmesis with a low reoperation rate.DOI: http://dx.doi.org/10.3329/kyamcj.v1i2.13317KYAMC Journal Vol.1(2) January 2011,64-69
Quality Assurance Scheme for Under Graduate Medical Institutions: A brief overview
Authors: Rahman Md. Mahfuzar
Published: May 2013

DOI: http://dx.doi.org/10.3329/kyamcj.v1i2.13319KYAMC Journal Vol.1(2) January 2011, 74-81
Off-Pump Total Myocardial Revascularization for Dextrocardia and Situs Inversus
Authors: Rahman Md. Lutfar , Chowdhury Md. Masumul Gani , Badruzzaman Dr , Kalam SMA
Published: May 2013

DOI: http://dx.doi.org/10.3329/kyamcj.v1i2.13320KYAMC Journal Vol.1(2) January 2011, 82-83
Double rare ABO blood group inheritance
Authors: Nandy CK , Begum Shahida , Uddin SM Jalal , Sengupta Ashim Kumar , Biswas Joly , Khatun Ayesha
Published: May 2013

Blood group system ABO phenotype Oh Bombay detected while cross-matching with different donors and by the by, family screening leads to a unusual matting result when mother AB and father O.DOI: http://dx.doi.org/10.3329/kyamcj.v1i2.13321KYAMC Journal Vol.1(2) January 2011, 84-86
Bleeding manifestation of post operative case in routine ENT surgery - a Caution for the young ENT Surgeons
Authors: Karim R , Hossain D , Martin MA
Published: May 2013

DOI: http://dx.doi.org/10.3329/kyamcj.v1i2.13322KYAMC Journal Vol.1(2) January 2011, 88-91
Sudden Cardiac Death (SCD) -One of the most difficult challenges in modern cardiology.
Authors: Islam Md Saiful
Published: May 2013

DOI: http://dx.doi.org/10.3329/kyamcj.v2i1.13511KYAMC Journal Vol.2(1) 2011 pp.92-95
Prevention of ischemic Stroke
Authors: Haque Badrul , Mohammad Quazi Deen , Ali Shah Md Keramot
Published: May 2013

Carotid atherosclerosis is associated with ischemic stroke. It is common in the elderly and the condition can be controlled or improved by drugs. In order to find out the role of antioxidant vitamins (beta carotene [USP 6 mg], Vitamin C [BP 200 mg] and Vitamin E [BP 50 mg]) and aspirin, aspirin and ACE- inhibitor (Ramipril) or aspirin alone in prevention of ischaemic stroke due to plaque in or near carotid artery bifurcation diagnosed by carotid color duplex ultrasonography and patients attended in Dhaka Medical College Hospital were studied to justify that these are effective.DOI: http://dx.doi.org/10.3329/kyamcj.v2i1.13512 KYAMC Journal Vol.2(1) 2011 pp.96-108
Prevalence of Renal Artery Stenosis in Patients Undergoing Routine Coronary Angiography
Authors: Sakib Md Annaz Mus , Talukder Ranjan , Morshed Maruf , Islam Md Saiful
Published: May 2013

This retrospective observational study aimed to see the angiographic association of at Renal-Artery Stenosis (RAS) with Coronary Artery Disease(CAD) in Bangladeshi population. It was conducted in the department of cardiology, Khwaja Yunus Ali Medical College and Hospital (KYAMCH), Enayetpur, Sirajgonj, Bangladesh, from January 2007 to January 2009.A total 281 patients with Ischaemic heart disease, on non emergent coronary angiogram who underwent either selective or non selective renal angiography were enrolled in this study. Among 281 patients, male patients was 241(85.76%), female was 40(14.23%) and age group was 30-75 years. Among those patients 228(81%) patients had Coronary artery disease, 53(18.86%) patients had normal coronary artery. Among CAD, 51(18.14%) patients had single vessel disease (SVD),39(13.87%) patients had double vessel disease (DVD),124(44.12%) patients had triple vessel disease(TVD) and 14(4.9%) patients had minimal coronary artery disease. RAS was detected 23(8.18%) patients and RAS with HTN was 18(78%) patients and ARAS without HTN was 5(21.73%) patients. RAS tends to increase with age. In age group 30-45 years, RAS was 17.39% and age group 50-75 it was 82.60%.The incidence of was high in50.09±8.76 years. Incidence of RAS was more common in male patients (73.91% vs. 26.08%).DOI: http://dx.doi.org/10.3329/kyamcj.v2i1.13513 KYAMC Journal Vol.2(1) 2011 pp.109-113
A comparative study of locally advanced oesophageal squamous cell carcinoma by radiation versus concurrent chemo-radiation
Authors: Sengupta Ashim Kr , Bhattacharjee Biswajit , Sharmin Meher Nigar , Bari MA , Hai MA
Published: May 2013

Aim: To observe the effects of radiation and concurrent chemo-radiation as treatment on locally advanced oesophageal carcinoma in human. Methods: Randomized prospective study was carried out in the Department of Radiotherapy, Dhaka Medical College and Hospital, Dhaka during the period of July 2001 to June 2002. Patients of locally advanced oesophageal carcinoma, histologically squamous cell carcinoma type was included in the study. After proper evaluation Arm-A was treated by concurrent chemotherapy weekly with Inj. Cisplatinum and Inj. 5-Flurouracil and conventional radiotherapy with a total dose of 44 Gy in 22 fractions in 4.5 weeks. Arm-B was treated by conventional radiotherapy with the same dose as that of Arm-A. Every patient was evaluated by monitoring routinely to see the responses. All the resultant informations were kept preserved on a prescribed data sheet. These informations were than analyzed statistically and results were compiled accordingly. Result: Out of 30 patients in Arm-A, complete desirable response was observed in 21 cases and partial response in 9 cases, where as out of 30 patients in Arm-B it was 13 and 17 cases respectively. Conclusion: Concurrent chemo-radiation showed better response than radiation alone, though toxicities were little bit higher but it was acceptable and easily manageable.DOI: http://dx.doi.org/10.3329/kyamcj.v2i1.13514 KYAMC Journal Vol.2(1) 2011 pp.114-117
Studies on lipid profile in patients with non insulin dependent diabetes mellitus
Authors: Choudhury Md Manzurur Rahman Shah , Alam Towhidul , Rahman AKM Shahidur
Published: May 2013

Diabetes mellitus is a global health problem and is associated with abnormalities of lipids and lipoprotein metabolism in variable frequency. The aim of the present work was to study the lipid abnormalities in NIDDM patients. Dyslipidaemia is of special interest because to compare it between male and female NIDDM patients and as well as to see the impact between women of reproductive age group and post menopausal women. For this purpose total serum cholesterol, triglyceride, LDL-C, HDL-C and LDL/HDL ratio were determined of a total number of 160 subjects. Out of these 80 subjects were diabetic and 80 were non-diabetic control subjects of both sexes. In this study, the total serum cholesterol levels were higher in NIDDM than control subjects and showed significant statistical difference (P<0.05) between control and NIDDM subjects. The serum triglyceride levels were found higher amongst diabetics as compared to the normal healthy controls and showed statistically significant difference (P<0.05). Higher LDL-C levels were showed in NIDDM and revealed significant difference (P<0.05) in comparison to control non-diabetic subjects and NIDDM patients. HDL-C levels were found decreased in patients with NIDDM compared to controls. The findings in the patients with NIDDM between male and female revealed no significant difference (P>0.05) in mean TC, TG, HDL-C and LDL-C between male and female diabetic patient in unpaired t-test. With improvement of diabetic control some improvement of the lipid abnormalities can be achieved. Most studies have shown that improvement of lipid abnormalities occur with proper glycaemic control in patients with NIDDM. The atherosclerotic process in the diabetic patient is indistinguishable from that seen in the non-diabetic population but it begins earlier and is more severe. Risk factors associated with atherosclerosis in the non-diabetic subject appear to have a similar relation to coronary heart disease among diabetics. Further studies are necessary to confirm the present suggestions, studies involving more number of subjects, estimation of Hb AIC.DOI: http://dx.doi.org/10.3329/kyamcj.v2i1.13516 KYAMC Journal Vol.2(1) 2011 pp.123-127
Study of referral pattern for psychiatric evaluation in psychiatric OPD in a rural tertiary care hospital
Authors: Shaikh Muhammad Abdul Kayum , Ali Md Zulfikar , Islam Md Saiful , Mokhlesuzzaman AKM
Published: May 2013

Health includes both physical and psychological well being of an individual. There is strong chance that every physical illness has psychological component and in many cases psychological disorders present with somatic symptoms; so psychiatric referral is very important to the proper management of a patient. The aim of this study was to find out the pattern of referral from different outpatient departments in a tertiary level hospital in rural setting of Bangladesh. In this descriptive study total 237 patients were evaluated in 7 months period and most of the diagnoses were anxiety disorders (40%), major depressive disorder (35%) and somatoform disorders (17%). Departments of medicine (cardiology 34%, internal medicine 28% and neurology 26%) referred most of the patients than the surgical or gynecological departments.DOI: http://dx.doi.org/10.3329/kyamcj.v2i1.13517 KYAMC Journal Vol.2(1) 2011 pp.128-131
Emerging Treatment Of Rheumatoid Arthritis - Use of Biologic Agents
Authors: Rahman Md Monzur
Published: May 2013

Until now there no curative treatment for Rheumatoid arthritis. As the pathogenesis of the disease is now greatly unveiled, and role of many immunologic key-molecules have been understood, new agents called 'biologic agents' are discovered, which are being used as therapeutic agents to target the key-molecules with great success. Remarkable results have been achieved ( even cure in significant number of cases, when treatment started early) when some of these agents are used in combination with Methotrexate. Notable among these agents are anti-TNF agents, IL-1 and IL-6 inhibitors, B-cell antagonists (e.g. Rituximab), T-cell blocking agents, RANKL inhibitors ( denosumab) etc. The main obstacle to their use is treir high cost, for which reason they out of reach of general people.DOI: http://dx.doi.org/10.3329/kyamcj.v2i1.13518 KYAMC Journal Vol.2(1) 2011 pp.132-139
Dislocation Of Shoulder Joint
Authors: Hafizuddin AH Ahmed
Published: May 2013

Dislocation means complete loss of contact of the articular surfaces of bony components of a joint. Shoulder joint is the most commonly dislocated large joint. Dislocation of shoulder joint has been recognized for centuries as an injury in both young and old.DOI: http://dx.doi.org/10.3329/kyamcj.v2i1.13519 KYAMC Journal Vol.2(1) 2011 pp.140-144
Arterial Thromboembolism in a patient with Ischemic Dilated Cradiomypathy (IDCM)
Authors: Islam Md Saiful , Hossain Md Alamgir , Talukder Ranjan , Moniruzzaman Md
Published: May 2013

Mrs. Shikha, 51 years old pleasant lady presented to us with the complaints of acute severe pain in the left leg associated with bluish discoloration for 5 days. She is a known case of Ischemic Dilated cardiomyopathy (IDCM) for last 6 years & had history of formation of LV thrombus for repeated times. She was on regular anti-platelets, anti-ischemic & anti-coagulant drugs. Recently her echocardiogram report revealed- IDCM, Mitral regurgitation (gr-11), spontaneous echo contrast within LV, LVEF- 24%. On this admission her CT coronary angiogram of lower limb vessels revealed total occlusion associated with thrombosis of left common iliac, external iliac & internal iliac, distal popliteal, ant. & post. tibial, peroneal arteries, & on right side diffuse atherosclerosis of distal popliteal, ant & post tibial arteries. Patient was treated with anticoagulants, anti platelet, anti-ischemic & other relevant medications & referred to vascular surgeon.DOI: http://dx.doi.org/10.3329/kyamcj.v2i1.13521 KYAMC Journal Vol.2(1) 2011 pp.149-151
Medical Education in Bangladesh: Problems and Prospects
Authors: Reza Hossain
Published: May 2013

DOI: http://dx.doi.org/10.3329/kyamcj.v2i2.13254KYAMC Journal Vol.2(2) January 2012 156-158
Bioequivalence study of FlunacTM and DiflucanTM in healthy Bangladeshi male volunteers
Authors: Sarker UK , Misbahuddin M , Hossain MA
Published: May 2013

A bioequivalence study of a local antifungal drug, fluconazole (FlunacTM), was compared with that of innovator product DiflucanTM. The study was conducted on 15 healthy volunteers and single cross-over dose of 150 mg fluconazole was administered orally. Two milliliter of blood was collected at different time intervals for 96 hours. The drug was extracted by liquid-liquid extraction and estimated by high performance liquid chromatography with diode array detector (260 nm). The chromatographic separation was accomplished using C18 analytical column with a mobile phase consisting of water and acetonitril (80:20, v/v). The Cmax of DiflucanTM and FlunacTM was 2.48 ± 0.29 g/mL and 2.23 ± 0.29 g/mL respectively. The Tmax of DiflucanTM and FlunacTM was 2.18 ± 0.98 hours and 2.56 ± 0.81 hours respectively. The area under the curve (0 to 96 hours) of DiflucanTM and FlunacTM was 73.28 ± 13.80 hours/mL and 74.49 ± 16.03 hours/mL. The half-life of both the drugs was 44.59 ± 13.79 hours for DiflucanTM and 42.73 ± 11.71 hour for FlunacTM. This study shows that FlunacTM is comparable to DiflucanTM in pharmacokinetic aspect.DOI: http://dx.doi.org/10.3329/kyamcj.v2i2.13255KYAMC Journal Vol.2(2) January 2012, 159-163
Depression in common dermatological patients attending outpatient department
Authors: Khan SMAH , Shaikh MAK , Ali MZ
Published: May 2013

Skin is the organ which covers our whole body and its condition directly influences our well being. Its psychological impacts are enormous, as evident by the efforts we put for taking care of our skin condition. The aim of this study was to find the presence of depression among the patients with dermatological disorders. Total 100 dermatological patients were assessed by the Hamilton Depression Rating Scale (HAM-D), 38% of patients had depression. Depression was highest in atopic dermatitis (71.43%), followed by psoriasis (58.82%), acne vulgaris (47.62%) and vitiligo (44.44%). Suicidal ideation was more common patient with atopic dermatitis (28.57%, 2 among 7) followed by psoriasis (23.53%, 4 among 17).DOI: http://dx.doi.org/10.3329/kyamcj.v2i2.13260KYAMC Journal Vol.2(2) January 2012, 164-171
Pattern of diseases in admitted patients in medicine unit 2 - in a rural tertiary medical institute period: January 1, 2010 - December 31, 2010
Authors: Mokhlesuzzaman AKM , Ali MZ , Shaikh MAK , Ripon SH , Uddin MM , Hoque MN
Published: May 2013

Existing disease pattern and health seeking behavior in a community should be known to provide need based quality service. The aim of this study was to find out the disease pattern, common diseases, age distribution, sex ratio, seasonal influence, comorbidity etc in admitted patients in Khwaja Yunus Ali Medical College & Hospital (KYAMCH), a rural tertiary care Hospital in Bangladesh. In this retrospective and descriptive study total 550 patients were evaluated in 1 year period who were admitted either from OPD or through Emergency. Most of the diagnoses were made after evaluation according to the organ system involved eg. Gastrointestinal, hepatobiliary & pancreatic (15%); Respiratory (24%); Infective (6.5%); Renal (11%); Neurological (24%); Haematological (2.75%); Endocrine (6.75%); Rheumatological (4%); Psychiatric & Poisoning (6%). Hope we will get a understanding of disease pattern among the admitted patients in a good organized way through this study. Furthermore, it will be possible to calculate the mortality, treatment success, hospital staying, total cost of treatment thus to estimate the disease burden and cost effectiveness as well.DOI: http://dx.doi.org/10.3329/kyamcj.v2i2.13261KYAMC Journal Vol.2(2) January 2012, 172-181
Prevalence of primary renal diseases among patients on maintenance haemodialysis: a hospital based study
Authors: Ahmed ST , Rahim MA , Ali Z , Iqbal MM
Published: May 2013

Background: Chronic Kidney Disease (CKD) is the third most common non-communicable disease throughout the world. Studies have shown that kidney patients suffer much from hypertension, diabetes than glomerulonephritis. Many of these CKD patients ultimately terminate to End Stage Renal Disease (ESRD) when life is not sustainable unless hemodialysis is initiated. Aim: The aim of this study was to identify primary renal disease leading to ESRD requiring hemodialysis and associated co-morbidities. Material and methods: Data was collected purposively from selected six hemodialysis centers. Patients were selected purposively who were available at the time of interview. Data was collected on working days at three shifts After taking informed consent from patients the pre-tested questionnaire was filled up by taking general history, family history, socioeconomic condition, drug history and available records were reviewed for collecting previous biochemical parameters. All entered data were analyzed by using SPSS program version 13.0. Result: Among total 393 subjects, male was 247(63%) and female 146 (37%). Majority were middle aged. Glomerulonephritis were found to be the leading cause of End Stage Renal Disease (ESRD) (50.4%), followed by diabetes in 31.1%, Poly Cystic Kidney Disease (PKD) 5.3%, Renal Stone in 3.7% and rest other. Among the study population hypertension was the most common co morbidity disease (63%) followed by ischemic heart disease and Cerebrovascular accidents. Conclusion: Glomerulonephritis was found to be the leading cause of End Stage Renal Disease (ESRD) and diabetic nephropathy was the second common cause. Hypertension was the most common associated co morbid disease. To evaluate the actual disease pattern a large scale study is required to find the outcome of haemodialysis patients.DOI: http://dx.doi.org/10.3329/kyamcj.v2i2.13262KYAMC Journal Vol.2(2) January 2012, 182-186
Development of APLAR-COPCORD Core Qestionnaire for Identification of Risk Factors for Non Specific low Back Pain
Authors: Siddiqui MNA , Islam MN , Haq SA , Sultana Shahnaj
Published: May 2013

Background: Non specific low back pain (NSLBP) has been identified as one of the commonest rheumatic disorders in prevalence surveys in Asia-Pacific. Objective: Development of a core questionnaire for identification of risk factors of NSLBP at community level. Methods: Following steps were followed: 1) item generation from literature survey, existing Nordic questionnaires and patient focus group discussions, 2) development of a preliminary APLARCOPCORD English questionnaire, 3) translation into target language, back translation and development of a synthetic target language version, 4) adaptation of the synthetic target language version through tests of comprehensibility, content validity test-retest reliability, and 5) finalization of the English questionnaire. Results: 45 items were generated. A preliminary English questionnaire was developed. Conclusion: The developed English questionnaire will serve as an efficient tool for identification of risk factors of NSLBP in Asia-Pacific communities.DOI: http://dx.doi.org/10.3329/kyamcj.v2i2.13263KYAMC Journal Vol.2(2) January 2012, 187-192
Perception and practice of waling exercise in morning walkers
Authors: Ansari MMH
Published: May 2013

Walking is the mostly preferred form of exercise for all ages. Brisk walking [5-6 kilometer per hour] for 30-60 minutes is an ideal one for a healthy person. A lot of people in urban Bangladesh do morning walk for cheering good health. This descriptive study was carried out among 208 morning walkers in Rajshahi Metropolitan area, selected purposively and was interviewed with a pre-tested close ended questionnaire for appraisal of their knowledge and practice of morning walking. The mean age of the respondents was 45.78 ± 13.01 years and majority of them (54.33%) had health problems including diabetes (35.58%). Almost all (92.30%) preferred walking in the morning. Majority respondents (64.42%) walked every day in the week and 64.90% spent one hour daily for it. Among the respondents, majority (60.58 %) had knowledge of one hour daily walking and 55.77% knew that daily walking coverage for two kilometers was the ideal. Only 3.63% of the morning walkers were found walked briskly and were scientifically correct in their practice. Most of the respondents with health problems had consulted with physicians but did not get proper guideline for walking. Physicians should advice their patients with detail about walking considering the age and the disease if they think it necessary. Health education program for acceptance of walking with correct information should be initiated and broadcast in mass media for general people.DOI: http://dx.doi.org/10.3329/kyamcj.v2i2.13264KYAMC Journal Vol.2(2) January 2012, 193-197
Sinus histiocytosis with lymphadenopathy - a case report
Authors: Ahmed SS , Ali MZ , Laila TR
Published: May 2013

Sinus histiocytosis with lymphadenopathy is a rare condition of unknown etiology that is characterized by the overproduction of histiocytes accumulating in the lymph node sinuses and in the lymphatics of extranodal sites if involved. Lymph nodes of the neck are the most common place of histiocyte accumulation, although other lymph nodes and organs may involve, as well. The common sites of the disease outside the lymph nodes are skin, soft tissues, upper respiratory tract, the sinuses, kidney, thyroid, small bowel, breast, and bone. Hepatosplenomegaly is uncommon. The symptoms of this disease vary with the site of involvement. It is often referred to as sinus histiocytosis with massive lymphadenopathy (SHML). In this article an adult male of 38 years, has been described who presented with bilateral cervical and axillary lymphadenopathy clinically suspected of infectious (tubercular-in the context of our country) or hematological malignant etiology. However on fine needle aspiration cytology, the smears showed many histiocytes, lymphocytes and plasma cells. Biopsy of cervical lymph node showed dilated sinuses filled with histiocytes and lymph node architecture showing inflammatory cells having lymphocytes and histiocytes. These findings were considered consistent with sinus histiocytosis with chronic lymphadenitis.DOI: http://dx.doi.org/10.3329/kyamcj.v2i2.13266KYAMC Journal Vol.2(2) January 2012, 205-208
Tradition of Adenoidectomy in children with recurrent URTI's
Authors: Karim R , Chowdhury AR , Hossain D
Published: May 2013

KYAMC Journal Vol.2(2) January 2012, 209-210
Information for Authors
Authors: Editor The
Published: May 2013

DOI: http://dx.doi.org/10.3329/kyamcj.v2i2.13268
Cancer Care- A Scenario in tertiary Rural Institute of Bangladesh
Authors: Ali Md Zulfikar
Published: May 2013

Not availableDOI: http://dx.doi.org/10.3329/kyamcj.v3i1.13654 KYAMC Journal Vol. 3, No.-1, June 2012 pp.210-213
Role of flexible cystoscopy and ultrasound in the detection of recurrent Bladder Tumour
Authors: Uddin Md Mohsin , Islam A K M Anwarul , Islam Md Saiful
Published: May 2013

Background: Rigid cystoscopy under anaesthesia for the surveillance of recurrent bladder tumour creates a large urological workload. Recently, flexible cystoscopy became a popular alternative and an easy, safe and effective means of check cystoscopy in following-up patients of superficial transitional cell carcinoma (TCC) of the urinary bladder. Because of the frequency of tumor recurrences and the necessity of finding, whether a less invasive, easily repeatable investigation is capable of providing precise information about the bladder cavity, and, could decrease the frequency of repeated rigid cystoscopy under anaesthesia and inpatient admission; we have decided to perform this study. Methods: This is a prospective comparative study that involved 85 patients (70 male and 15 female) with a mean age of 61 years (41-80 years), who had undergone one or more transurethral resections for TCC of bladder (stage pTa and pT1; grade I and II.) in the department of Urology, BSMMU between July 2005 -Feb 2007. Ultrasonography(USG) of the bladder was performed one week before check cystoscopy. We have calculated sensitivity and accuracy of USG and flexible in comparison to rigid cystoscopy.Results: Eighty five (85) sessions of follow-up investigations- Ultrasound and flexible cystoscopy showed 31 recurrences confirmed by rigid cystoscopy and biopsy. In over 85 rigid cystoscopies, 54 were negative and 31 were positive for tumour. Sensitivity, the most important parameter, was 97% for the two examinations together. Each method separately had the following sensitivity: ultrasound 77%; flexible cystoscopy 90%.Conclusion: Considering that there was only one false-negative result of combined abdominal ultrasound and flexible cystoscopy; with this follow-up scheme we could have saved our patient from rigid cystoscopies, reducing the cost of in-patient admission and anaesthesia.DOI: http://dx.doi.org/10.3329/kyamcj.v3i1.13655 KYAMC Journal Vol. 3, No.-1, June 2012 pp.214-219
Study of disease pattern of patients admitted in Gynae & Obst. Department in a rural tertiary medical institute
Authors: Sultana Mst Atia , Akter Monira , Noor Tahmina , Hossain Mahbub
Published: May 2013

The aim of this study was to find out the Gynaecological disease pattern, common diseases, age  distribution , organs involvement of female reproductive system, types of diseases etc. in admitted  patient of Khwaja Yunus Ali Medical College & Hospital (KYAMCH) a rural tertiary hospital in  Bangladesh. In this retrospective & descriptive study total 853 Gynaecological patients were  evaluated in 4 years period, who were admitted either from OPD or through emergency. Most of  the diagnosis were made after evaluation of organ involvement, 53% uterine origin, most are  benign 29%; 40% patient having normal menstrual cycle but suffering from Gynaecological  diseases like chronic cervicitis, lower abdominal pain(PID). Vaginal discharge, urinary tract  infection, ectopic pregnancy, different types of abortion. This study showed that the Gynaecological  disease pattern of Patients admitted in Obs& Gynae department of KYAMCH- a rural tertiary  medical institute.DOI: http://dx.doi.org/10.3329/kyamcj.v3i1.13656 KYAMC Journal Vol. 3, No.-1, June 2012 pp.220-222
Spectrum of heart diseases on Echocardiography in a Rural tertiary care Medical college hospital in Bangladesh
Authors: Islam Md Saiful , Sakib Md Annaz Mus , Talukder Ranjan , Yusuf Sheikh Mohammed Taslim
Published: May 2013

Background: Echocardiography is a non-invasive, on-injurious, relatively cheap and useful   imaging technique for the evaluation of cardiac diseases. The procedure has reliable levels of  accuracy. Echocardiography commenced at the Cardiology Department of Khawja Yunus Ali   Medical College Hospital,Enayetpur Sirajgonj,Bangladesh since 2004.The aim of this study is to  report our experience with the procedure, and to define the clinical cases seen in our setting.Methods: This is a retrospective analysis of a prospectively collected data. Echocardiography was  performed using Aloka Prosound-SSD 5500 SV echocardiograph equipped with 2.5-5.0 MHz   transducer.  Results: During the period of 6 months under review (July 2011-December 2011), 1883 procedures  were performed. Those reports were reviewed for demographic parameter, indications for the procedure and the main echocardiographic diagnoses. The mean age of the 1883 individuals   studied was 50 +/- 18.67 years (10-90). There were 1221 men and 662 women. Four hundred   ninety eight(498) (26.45%) had Ischemic Heart Disease, 229(12.16%) subjects were Hypertensive Heart disease,160 subjects (8.5%) had rheumatic heart disease while 62,(3.3%) had   cardiomyopathy. Pericardial diseases, corpulmonale, congenital heart diseases, were present in 36(1.92%), 35 (1.85%), 88(4.67%), respectively. Seven hundred and Seventy Five (41.1%) subjects had normal study.   Conclusion: Ischemic heart disease was found to be the most prevalent cardiac condition in this study. The relatively frequent diagnoses of Hypertensive heart Disease, valvular heart disease, cardiomyopathies and pericardial diseases reflect the impact of infections on the cardiovascular   health of adult Bangladeshis. We suggest that prevention and treatment of cardiac diseases in our setting should among other things focus on life style modification, Ceasation of smoking,regular exercise, blood pressure and blood glucose control and early treatment of infections causing heart   diseases.DOI: http://dx.doi.org/10.3329/kyamcj.v3i1.13657KYAMC Journal Vol. 3, No.-1, June 2012 p.223-224
Studies on microscopic technique and culture on Sabouraud's dextrose agar medium for diagnosis of dermatophytes infection
Authors: Khan Md Abul Abul Hossain , Khan S M Atique Hasan , Sarker Mahbub Rashid , Hussain Rubiyat Farzana , Ahmed Mejbah Uddin , Joarder Yasmin , Hasan Md Bulbul
Published: May 2013

Dermatophytoses (a fungal infection of the skin, hair and nail, usually caused by dermatophytes) constitutes an important public health problem because of its high prevalence and associated morbidity but not life-threatening. Three genera of dermatophytes are recognized based on the site and pattern of fungal invasion. Dermatophytes are the predominant pathogenic mould, but yeasts (especially Candida albicans) and non-dermatophytic moulds may also be implicated. For accurate diagnosis of dermatophytoses requires microscopic demonstration and isolation and identification by culture. This study evaluates the usefulness of microscopic technique and culture for the isolation and identification of dermatophytes from clinical samples. Thirty samples were included in this study for detection of fungal elements by both methods but sensitivity of microscopic demonstration and culture were 60.0% and 66.7% respectively. As the sensitivity of microscopic demonstration (60.0%) is almost equal to the isolation and identification rate (66.7%), requires further evaluation in large scale as its ready to use format makes the application and microscopy much easier and faster.DOI: http://dx.doi.org/10.3329/kyamcj.v3i1.13658 KYAMC Journal Vol. 3, No.-1, June 2012 pp.235-238