bluuebunny/crossref_metadata_2025 huggingface dataset:
Rebelia i reakcja
Authors: Marzec Wiktor
Published: September 2024

Rebelia i reakcja to studium plebejskiego doświadczenia politycznego w czasie rewolucji lat 1905–1907. Praca analizuje uczestnictwo robotników w życiu publicznym i ideologiczne obrazy świata u progu „politycznej nowoczesności”. Wtedy to stare podstawy ładu społeczno-politycznego zaczęły kruszeć, nowe grupy ludności domagały się politycznego głosu i ukształtowały się języki polityczne nowoczesnych obozów ideowych. Nowe formy polityki spotkały się z silną, konserwatywną reakcją, która na długi czas ukształtowała polską sferę publiczną. Książka opisuje również nacjonalistyczną odpowiedź na rewolucję oraz zmianę politycznego myślenia Narodowej Demokracji przed, po i w trakcie tych wydarzeń. Przedstawia praktyki publiczne robotników, analizując związane z nimi doświadczenie polityczne. Proponuje ponadto analizę transformacji pola politycznego i zmiennych tożsamości politycznych mobilizowanej masowo ludności.
Słowo
Authors: Szkudlarek-Śmiechowicz Ewa , Wierzbicka Agnieszka , Olejniczak Elwira
Published: September 2024

Monografia stanowi kontynuację badań nad współczesną polszczyzną prowadzonych przez łódzkich językoznawców. Autorami są również wybitni badacze, m.in. z Uniwersytetu Warszawskiego, Uniwersytetu Marii Curie-Skłodowskiej w Lublinie, Uniwersytetu Śląskiego w Katowicach, a także uznani specjaliści z innych dyscyplin humanistycznych: literaturoznawstwa, kulturoznawstwa, prawa, filozofii oraz nauk społecznych (wiedzy o mediach i komunikacji społecznej). Publikacja poświęcona jest słowu jako jednostce systemu, tekstu i dyskursu. Autorzy skoncentrowali się na wartości słowa, analizie wybranych leksemów oraz słowach w określonych typach tekstów i dyskursów.
Mamy nadzieję, że lektura najnowszego tomu dotyczącego słowa, które stało się przedmiotem dociekań tak wielu badaczy reprezentujących różne dyscypliny i ośrodki naukowe, będzie wartościową oraz intelektualną podróżą po świecie form, znaczeń i kontekstów jednostek leksykalnych. Być może zainspiruje do podjęcia dalszych badań, a na pewno zwróci uwagę Czytelników na wyjątkową rolę słowa zarówno w życiu każdego użytkownika języka z osobna, jak i w życiu określonej wspólnoty dyskursywnej, wspólnoty komunikacyjnej czy – jeszcze szerzej – w życiu społeczeństw, które są nie tylko wyrazicielami słów, lecz także są przez słowa konstytuowane i kształtowane.
Redaktorki
Słowo, dźwięk, cisza
Authors: Bachura-Wojtasik Joanna , Kowalska-Elkader Natalia
Published: September 2024

Zbiór Słowo, dźwięk, cisza. Radio i sztuka audialna – poświęcony przede wszystkim nowym i najnowszym formom działalności radiowej, ze szczególnym uwzględnieniem przedsięwzięć artystycznych zasługujących na miano sztuki – wydaje się interesującą propozycją wydawniczą. Analizowane są tu nie tylko „aplikacje mobilne”, „podcasty” i „platformy agregujące”, lecz także słuchowiska, tradycyjne i eksperymentalne, problemy obecności radia w szkole i edukacji czy zagadnienia „formy” w ujęciu Witkacego oraz innych teoretyków. Różnorodność tematów nie jest jego wadą. […] Autorzy przekonują nas, że o radiu można wciąż mówić i pisać rozmaicie, ale w każdym razie pisać warto, bo jest ono znaczącym elementem zarówno naszej kultury, jak i cywilizacji cyfrowej.
Z recenzji prof. dr. hab. Jana Tomkowskiego
Microflore bactérienne normale vaginale et préputiale chez les bovins au Sénégal
Authors: Konté M.
Published: September 2024

L'auteur procède à un inventaire bactériologique systématique des segments génitaux externes, vestibulo-vaginal et préputial, des bovins locaux et importés, mâles et femelles, cliniquement normaux. Il s'efforce de définir la nature des relations existant entre le profil général de la microflore, le pH et les facteurs d'environnment afin de déterminer le caractère infectieux ou symbiotique, strict ou non, de ces résidents.
COMPARATIVE GYNOCRITICISM OF BRONTE’S WUTHERING HEIGHTS AND ROY’S THE GOD OF SMALL THINGS
Authors: Genç Melisa
Published: September 2024

The present paper focuses on two influential female novelists and their ardent endeavours to claim a gender-specific structure and voice within the discourse of the novel. Emily Bronte and Arundhati Roy nauseated their contemporary readers and most of the critics by making use of bi-sexuality and incest as salient structural and thematic features of their narrative. In Wuthering Heights, both thematic and structural elements of Bronte’s feminine narrative operate as meta-narratives reverberating with the becoming of Bronte as a female novelist. The particular impinge of Bronte’s feminine narrative on the discourse of the novel reveals itself through the reversal of the oedipal projectile motion of history. Similarly, Arundhati Roy has weaponized her Indianized language to break from the strict linguistic laws of the symbolic so that the semiotic or the maternal realm has become blatant in The God of Small Things. Like Bronte, Roy wields incest and bi-sexuality to prevent the phallic development of the grand history; instead of the oedipal identity formation process, she displays the motif of incest as an opponent of a linear progression of the hero. Consequently, this study emphasises the differentiation of the two female novelists from the monolithic discourse in the novel. It also explains how feminine narrative structure owing to its immanent on-hand polyphony and bi-sexuality goes hand in hand with what Bakhtin calls heteroglossia and dialogic discourse in the novel.
PERTANGGUNG JAWABAN ORANGTUA TERHADAP ANAK YANG BEKERJA UNTUK MEMBANTU PEREKONOMIAN KELUARGA PERSPEKTIF MAQASHID SYARIAH DAN UU NO 35 TAHUN 2014 PERUBAHAN ATAS UU NO 2002 TENTANG PERLINDUNGAN ANAK (Studi Kasus di Kecamatan Seteluk Kabupaten Sumbawa Barat)
Authors: Sherina Pramasela  , Hery Zarkasih
Published: September 2024

This research was motivated by researchers' attention to the phenomenon of minors working as the backbone of the family in Seteluk District, West Sumbawa Regency. The type of method used is a qualitative method with a juridical-empirical research approach. The data collection methods used were observation and interviews. The researcher explains the form of parental coverage for children who work to help the family's economy in Seteluk District, West Sumbawa Regency, and uses children, parents, and village and sub-district governments as primary data sources. Data collection techniques in this thesis are observation and interviews. The data that has been collected is then analyzed and conclusions are drawn. The results of this research are the first form of parental coverage for children    who work  to help the family economy in Seteluk District, West Sumbawa Regency, namely providing         a living         and               good                      nutrition,                          giving education rights to some working children, and giving children the right to participate.
Cash Waqf as an Alternative Source of Islamic Microfinance Institution’s Capital in Indonesia
Authors: Gustani Gustani , Ernawan Dwi Aditya
Published: September 2024

One type of contemporary waqf is cash waqf. Cash Waqf provide more giving mashlahah because the money can be used for many things other than endowments. Form of cash waqf development is to be invested in Islamic financial institutions were profitable and secure. This paper aims to integrate the cash waqf as a social fund to the financial intermediation role on Islamic Micro Finance Institutions. Endowments in cash will be an alternative source of capital LKMS cheap and mashlahah. The pattern is divided into a cash waqf endowments temporary cash invested in sharia-term investment products, such as savings deposits and capital investments. Average cash waqf permanently included as a component of capital. Endowment funds will be disbursed on micro-finance, the results of which will be channelled to the social fund. With this pattern expected cash waqf and where LKMS can benefit the wider community.
“Round Peg in a Square Hole”: Lessons from Community Health Promotion Practice on Dynamics of Accountability, Reporting and Evaluation, and Governance
Authors: Fursova Julia , Kranias Gillian
Published: September 2024

This paper presents results from a small-scale institutional ethnography study of reporting requirements and evaluation practices in two urban community health centers (CHCs), as a sample of community-based nonprofit organizations that focus on social justice and health equity. The study illuminated complex relationships among accountability, reporting and evaluation, and governance. Among the CHCs, reporting and evaluation practices consistent with goals of obtaining social justice and health equity were undermined by an imbalance toward funder-oriented functional accountability. Analysis of accountability and reporting practices as systemic factors shaping knowledge production, decision-making, and action revealed notable consequences for CHCs’ health promotion practice. This paper proposes a wholistic accountability model to encourage equitable power relations in evaluation, enable participatory methods, and better align CHC knowledge production and governance systems with their health promotion goals. This study further adds to the growing literature supporting critical attention to nonprofit accountability in the context of systems change work.
Relationship of Fracture Morphological Characteristics with Posterolateral Corner Injuries in Hyperextension Varus Tibial Plateau Fractures
Authors: Wang Binghao , Ye Teng , Zhang Binbin , Wang Yukai , Zhu Yi , Luo Congfeng
Published: September 2024

Background:

Hyperextension varus tibial plateau fracture (HVTPF) is known to present with concomitant injuries to the posterolateral corner (PLC). However, the exact rate and characteristics of these injuries remain unclear. The primary objective of this study was to explore the rate and characteristics of PLC injuries in HVTPFs. The secondary objective was to investigate the relationship between the fracture morphological features and the associated PLC injuries.

Methods:

Patients with HVTPFs were subdivided into 2 groups: group I (without fracture of the posterior column cortex) and group II (with fracture of the posterior column cortex). Fracture characteristics were summarized qualitatively based on fracture maps and quantitatively based on the counts of morphological parameters. Knee ligamentous and meniscal injuries were assessed using magnetic resonance imaging. The association between fracture characteristics and PLC injuries was analyzed.

Results:

We included a total of 50 patients with HVTPFs in our study: 28 in group I and 22 in group II. The rate of PLC injuries was 28.6% in group I and 27.3% in group II. In group I, patients with PLC injuries showed fracture lines closer to the anterior rim of the medial plateau and had smaller fracture areas. Furthermore, 6 of the 8 patients with PLC injuries in group I also had posterior cruciate ligament injuries.

Conclusions:

The rate of PLC injuries is relatively high in HVTPFs. In HVTPFs without fracture of the posterior column cortex, a small fracture area strongly suggests an accompanying PLC injury, and PLC injury is frequently combined with posterior cruciate ligament injury.

Level of Evidence:

Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Outcomes of Total Knee Arthroplasty Following a Sham Incision Procedure in Patients with Previous Knee Incisions
Authors: Zink Thomas M. , Gonzalez Alexis G. , Coden Gloria , Smith Eric L. , Bono James V.
Published: September 2024

Background:

Tenuous blood supply carries a risk of wound-healing problems and subsequent infection following total knee arthroplasty (TKA). This risk may be increased by the presence of previous incisions. Performing a sham incision procedure allows for detection of wound-healing problems prior to performing TKA. The purpose of this retrospective case series is to describe the indications for and technique of a sham incision procedure in patients with previous knee incisions who underwent TKA following this procedure and to report the clinical outcomes observed in these patients following further surgery.

Methods:

Patients who had prior knee incisions, had undergone a sham incision prior to TKA, and had a minimum follow-up of 2 years were identified, and their cases were retrospectively reviewed. The identified cases typically adhered to the surgeon’s standard protocol, which consisted of making a midline incision adventitious to TKA, dissecting down to deep fascia, and closing the wound with suture. Incisions were then observed for at least 4 weeks to determine the viability of the skin flaps before TKA was performed via the same incision.

Results:

A total of 47 knees in 47 patients were included in the study cohort. TKA was performed at an average of 21.1 weeks (range, 4 to 163 weeks) following the sham incision. There were no cases of skin necrosis or periprosthetic joint infection at an average follow-up of 4.6 years (range, 2 to 12 years) after sham incision. A total of 11 patients (23.4%) required manipulation under anesthesia for stiffness.

Conclusions:

In our series, no patients developed skin necrosis or periprosthetic joint infection following TKA subsequent to a sham incision procedure, suggesting that healed sham incisions are safe to use for TKA and may be considered prior to TKA in cases in which local previous incisions increase the risk of wound-healing problems.

Level of Evidence:

Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Genomic analysis of antimicrobial resistant Escherichia coli isolated from manure and manured agricultural grasslands
Authors: Walsh Fiona , Leigh Robert , Drissner David , Münzenmaier Diana , Brennan Fiona , Burgess Catherine , Tyrrell Ciara
Published: September 2024

Antimicrobial resistance (AMR) is a multifactorial issue involving an intertwining relationship between animals, humans and the environment. The environment can harbour bacteria that are pathogenic to human health, including Escherichia coli, an indicator of environmental faecal contamination. Through culture dependent approaches this study identified 46 E. coli isolates in porcine and bovine manure, non-manured and manured soil, and the phyllosphere of manured grass. The grass isolation highlights grass as an environmental reservoir for E. coli. Whole genome sequencing identified 11 different multi-locus sequence types. We also identified a diverse plasmidome with 23 different plasmid replicon types. The E. coli isolates were phenotypically antibiotic resistance, predominantly multidrug resistant. Additionally, whole genome sequencing identified 31 antibiotic resistance genes, and mutations in the gyrA, parC, and parE genes, conferring fluoroquinolone resistance. The main virulence genes were associated actin mediated locomotion (icsP/sopA), siderophore production and alginate production (algA), which suggest adaptation to survive in the non-gut environment or the UV environment of grass surfaces. These results suggest that E. coli in soils and grasses may adapt to their new environments evolving novel strategies. This study demonstrates grass as an understudied environmental niche of AMR E. coli, which directly links the environment to the grass grazing animal and vice-versa via the circular economy of manure application.
A First Model Foundation Design of Wood Pillar in Swampland
Authors: Agusniansyah Nursyarif , Sarbini Gusti Novi , Rahman Akbar , Tharziansyah Muhammad
Published: September 2024

Swampy land in Banjarmasin has special characteristics for building house constructions. The foundation for very low soil bearing capacity requires special treatment as well. Many building collapses are caused by foundation failures due to mismatched building loads and foundation functions, as well as construction material errors. The need for house design follows the development of building functions. Nowadays, a one-story house is no longer sufficient due to limited land. The need to elevate houses to two stories or to develop houses (renovations) often leads to foundation construction errors. The commonly used foundation, wooden pile foundation, has limited load-bearing capacity, necessitating modification steps in the form of foundation reinforcement. Several steps, including material combinations or combinations of various types of foundations, can be implemented. Therefore, a specific model is required to obtain a foundation design that can accommodate construction needs. The aim of the research is to create a foundation design model capable of reinforcing wooden pile foundations for both house construction development and as a reference for building one-story and two-story houses. In this research, field observations will be conducted at various house construction sites in Banjarmasin, both residential and individual objects. Data will be presented descriptively and analyzed to obtain an applicable model as a reference for house construction on swampy land. The model will provide an applicable depiction and will be tested against foundation construction implementation methods.
NIPT/NIPT plus combined with ultrasound in screening fetal chromosomal abnormalities：a retrospective study
Authors: Chen# Meilin , Yan# Jinghai , Yu# Siyang , Ai Lu , Yu Xuegao , Wang Ruizhi , Chen Peisong , Lin Shaobin
Published: September 2024

Introduction: This is a retrospective study of 306 pregnant women of which 182 had genetic testing with NIPT plus and CMA, and another 124 had genetic testing with standard NIPT and CMA. To compare the clinical performance of NIPT and NIPT plus in prenatal evaluation, and the NIPT results were compared to CMA as the gold standard to analyze the diagnostic efficiency of the two NIPT methods. Methods: By analyzing the NIPT Plus/NIPT results and correlating them with the ultrasound results, we evaluated the accuracy and clinical utility of this approach. Finally, the results of CMA were compared as the gold standard to analyze the diagnostic efficiency of the two methods. Results: It showed that the combined diagnosis of NIPT Plus and ultrasound had a higher detection rate than the combined diagnosis of NIPT and ultrasound. The positive predictive value of the combined diagnosis of NIPT and ultrasound was as high as 100% in our study. Conclusion: NIPT plus has a higher false positive rate, which emphasizes the need for combining ultrasound in the screening process to provide clinical guidance. Screening for sex chromosome aneuploidy in fetuses, using NIPT alone, may be superior to combined screening with ultrasound.
Genetic diversity and relationships among Iris aucheri genotypes determined via ISSR and CDDP markers
Authors: Rasul Kamaran Salh , Majeed Hoshman Omar , Faraj Jamal Mahmood , Lateef Djshwar Dhahir , Tahir Nawroz Abdul-razzak
Published: September 2024

Iris aucheri, which belongs to the Iridaceae family, is one of the most important wild ornamental plants distributed widely throughout the Iraqi Kurdistan Region (IKR) (north of Iraq). The genetic diversity of this plant species is partly known. Thus, ten ISSR markers and ten CDDP markers were utilized to evaluate the genetic diversity and perform population analysis of forty-eightwild Iris aucheri genotypes from five locations in the IKR. The results revealed 108 and 134 polymorphic bands for the ISSR and CDDP markers, respectively. The mean values of the number of observed alleles (Na), effective number of alleles (Ne), Shannon's information index (I), expected heterozygosity or gene diversity (He), unbiased expected heterozygosity (uHe), and polymorphic information content (PIC) were 1.71, 1.43, 0.39, 0.26, 0.27, and 0.32 for the ISSR primers and 1.53, 1.37, 0.34, 0.22, 0.23, and 0.26 for the CDDP primers, respectively. All the genotypes were classified into two main clades and two populations on the basis of the UPGMA dendrogram and population structure analysis derived from the marker data. The variation within populations was 89.59%, 90.64%, and 90.31% for ISSR, CDDP, and combinations of both markers, respectively. Among all the data, population 2 presented the highest values of the majority of diversity indices. Our results revealed the efficacy of both markers in determining the genetic variability among iris genotypes. This is the first attempt to use these markers to elucidate genetic diversity among I. aucheri plants. These findings can be used in germplasm conservation and future breeding plans.
Optimization of uprooting efficiency of counter-rotating cotton stalk puller for on-field operations
Authors: Pandirwar Ashutosh , Pandey HIMANSHU , Magar AJIT P , Roul AJAY K , Kumar MANOJ , Jyoti BIKRAM
Published: September 2024

Background
Cotton stalks, a by-product left after cotton picking, have several industrial applications as a raw material. However, due to deep taproot system, the uprooting and disposal of cotton stalks from the field is a labour-intensive operation. In this study, the uprooting efficiency of a counter-rotating drum type cotton stalk puller (CSP) was optimized using Response Surface Methodology (RSM) and combined Artificial Neural Network (ANN) - Particle Swarm Optimization (PSO) approach. Machine operational parameters and design parameter were independent variables, whereas, uprooting efficiency, plants broken and plants left were response variables.
Results
An experimental CSP unit was operated in field at three forward speeds (1.37, 1.67 and 1.95 km/h), four drum speeds (250, 300, 350 and 400 rpm) and three drum inclinations (00, 100, 200). The optimization using RSM shown 332.5 rpm drum speed, 8.360 drum inclination and 1.37 km/h forward speed as optimal values. Plants uprooted, plants broken and plants left have optimum values of 96.6%, 2.8% and 1.1% with individual desirability of 0.97, 0.85 and 0.89 showing the closeness of responses to predicted values. ANN-PSO model shown optimal parameters as 1.37 km/h forward speed, 7.890 drum inclination and 331.45 rpm drum speed with the observed and predicted values of uprooting efficiency are 96.72% and 94.84%, respectively.
Conclusion
The results show that both RSM and combined ANN-PSO approach can better predict and optimize the performance of CSP with higher accuracy. Optimization study provide essential information on optimal combination of operating and design parameters for enhanced uprooting efficiency with minimum plant breakage.
HDAC3 inhibitors induce drug resistance by promoting IL-17A production by T cells
Authors: Chen Hao , Qin Anqi , Xu Fan , Guo Shuai , Zhang Ge , Zhang Aihong , Li WenTing , Tian Feng , Zheng Quanhui
Published: September 2024

HDAC3 has been demonstrated to play a crucial role in the progression of various tumors and the differentiation and development of T cells. However, its impact on peripheral T cells in the development of murine lung cancer remains unclear. In this experiment, a subcutaneous lung tumor model was established in C57BL/6 mice, and tumor-bearing mice were treated with the specific inhibitor of HDAC3, RGFP966, at different doses to observe changes in tumor size. Additionally, a lung tumor model was established using hdac3fl/fl cd4cre+/+ mice to investigate its mechanism. Mice injected with 10mg/kg RGFP966 had the smallest tumor volume, while those injected with 30mg/kg RGFP966 had the largest tumors. Flow cytometry analysis revealed that the expression of HDAC3 in splenic T cells was reduced in all groups of mice, while IFN-γ and IL-17A were increased. Moreover, the expression of granzyme B and perforin in splenic CD8+ T cells was increased in all groups of mice. Compared to the use of 30mg/kg RGFP966 alone, the combination with anti-IL-17A mAb reduced the infiltration of Neutrophils and exhausted T cells in mouse tumors, thereby impeding tumor development. These findings demonstrate that the use of RGFP966 or T cell-specific loss of hdac3 promotes the expression of IL-17A in splenic T cells, leading to tumor resistance and providing insights for clinical treatment.
Effect of High‑Fat-Diet and Semaglutide on Bladder Cancer in Mice
Authors: Liu Yanhui , Ban Jiangli , Yang Lin , Pan Xiaoyu , Zhen Ruoxi , Jia Zhuoya , Chen Shuchun
Published: September 2024

Objective The aim of this study is to examine the proteomics of adipose tissue in mice with obesity induced by a high-fat diet, in order to investigate how obesity affects the protein expression profile of adipose tissue. Additionally, we seek to establish a foundation for understanding the mechanism through which semaglutide may impact bladder cancer (BLCA) associated with obesity.Methods Thirty-six male C57BL/6J mice, all in good health, were chosen and divided into three groups: a group fed a normal diet (referred to as the NCD group), a group fed a high-fat diet (known as the HFD group), and a group fed a high-fat diet along with semaglutide treatment (referred to as the Sema group). We examined how obesity affects serum markers and how semaglutide influences these markers. Additionally, we investigated changes in protein expression within BLCA using proteomics techniques. By employing bioinformatics methods, we identified differentially expressed proteins that may be associated with the hypothesized mechanism of semaglutide's potential for reducing bladder cancer risk.Results Our findings indicate that semaglutide has the potential to decrease body weight, enhance glucose metabolism, and improve blood lipid levels. The alterations observed in the expression of Lama2 ( laminin subunit alpha-2), Lama4 (laminin subunit alpha 4), Lamc1 (laminin subunit gamma 1), Thbs2 (thrombospondin 2) genes across the normal group, high fat group, and semaglutide group primarily involve the extracellular matrix (ECM) pathway. Following intervention with semaglutide, a significant reduction in the expression of various proteins was observed in BLCA. These results suggest that by modulating genes such as Lama2, Lama4, Lamc1, Thbs2 and others, semaglutide may potentially mitigate the risk associated with BLCA.Conclusion Semaglutide exhibits potential in mitigating obesity induced by a high-fat diet and delaying the onset and progression of bladder cancer. The activation of Lama2, Lama4, Lamc1, Thbs2, and their involvement in the ECM pathway may underlie the mechanism through which semaglutide exerts its effects on bladder cancer.
Dynamic Scheduling Strategies for Load Balancing in Parallel and Distributed Systems
Authors: Albalawi Nasser
Published: September 2024

Actual load balancing in parallel and distributed systems ruins a serious task owing to the dynamic nature of workloads and the availability of resources. Existing scheduling procedures continually fail to regulate real-time alterations, leading to suboptimal performance and resource underutilization. Our study validates dynamic and effective load distribution by combining novel systems and optimization techniques to handle these issues. To provide efficient load balancing in distributed and parallel systems, we utilize a comprehensive dynamic scheduling approach in this work. In this example, we start by using Round-Robin Allocation with Sunflower Whale Optimization (RRA-SWO) to perform an allocation procedure. The allocation step is followed by the Hybrid Ant Genetic Algorithm (HAGA), which is used to schedule tasks in parallel. The Least Response Time (LRT) technique for the Load Monitoring procedures will be developed once the job scheduling is complete. The Harmony Search Algorithm with Linear Regression (LR-HSA) is then used to do Distributed Computing-based Load Prediction and Adjustment. Alongside ongoing observation, this is carried out. Finally, we use the Least Recently Used (LRU) technique to do dynamic load balancing. We build and test our methods CloudSim and NetBeans 12.3 are used on a Windows 11 64-bit. Throughput, Packet Delivery Ratio, Average Response Time, Task Success Rate, Memory Utilization Rate, and Throughput are all analyzed to validate our strategy.
Determinants of Depression and Anxiety in Informal Waste Pickers: A Cross-Sectional Study of Informal Waste Pickers in Hong Kong
Authors: CHAN SIU MING , Xu HENG , TANG YUEN KI , ZHANG Jasmine , KWOK KIM , LAM Bess YIN HUNG , TANG WING HIM , LUI KA CHUN
Published: September 2024

Background
There are growing global concerns about informal waste pickers and their health issues. This cross-sectional study drew on the structural violence theory to examine the mental health situation of informal waste pickers in Hong Kong and identified the determinants of depression and anxiety in them ranging from individual to societal and governmental levels.
Method
The data from the largest territory-wide study of informal waste pickers in 2023 was analysed. Descriptive statistics and logistic regressions were used to investigate the association between mental health and socioeconomic variables, including demographic background, governmental measures against informal waste pickers, other negative experiences related to safety and public discrimination, and supportive resources. The symptoms of depression and anxiety were assessed using the Patient Health Questionnaire (PHQ) and General Anxiety Disorder (GAD).
Results
The results showed that physical strain/illness and chronic illness caused by long-term scavenging works (for depression adjusted OR 3.33, 95% CI [1.75, 6.31]; for anxiety adjusted OR 5.01, 95% CI [2.45, 10.24]), recycling or personal property stolen (for depression adjusted OR 2.04, 95% CI [1.23, 3.36]; for anxiety adjusted OR 2.72, 95% CI [1.62, 4.56]), being treated rudely by citizens (for depression adjusted OR 2.16, 95% CI [1.32, 3.55]); for anxiety (adjusted OR 2.85, 95% CI [1.74, 4.67]) are the critical risk factors of informal waste pickers’ mental health. While higher intention to continue scavenging work if financial conditions permit is the critical protective factor for depression (adjusted OR 0.46, 95% CI [0.24, 0.88]) and anxiety (adjusted OR 0.43, 95% CI [0.22, 0.86]), compared to lower intention to continue scavenging work if financial conditions permit in the multivariate model.
Conclusions
This study discloses the close relationship between informal waste pickers’ long-term physical strain/illness and mental health and identifies the governmental measures, other negative experiences related to safety issues and public discrimination as risk factors for informal waste pickers’ mental health. Providing outreach, tailored medical services, increasing the unit price of recycling, developing specific recycling zones and establishing membership-based organisations help alleviate the challenges of precarious employment and enhance the well-being of the informal waste pickers.
Impact of electronic cigarette vaping on the cardiovascular functions in young and old rats
Authors: Dai Wangde , Shi Jianru , Carreno Juan , Kleinman Michael T , Herman David A. , Arechavala Rebecca J. , Renusch Samantha , Hasen Irene , Ting Amanda , Kloner Robert
Published: September 2024

Background
While the acute exposure to electronic cigarette (E-cig) vapor has been associated with an increase in blood pressure, the chronic effect of E-cig vapor on blood pressure compared to standard cigarette smoke has not been extensively studied. We determined the effect of E-cig exposure on blood pressure and other cardiac functional measures in both young and old rats.
Methods
Young Sprague Dawley rats (6 weeks old, both sexes) were randomly exposed to air (n = 34), E-cig with nicotine (E-cig Nic+; n = 30), E-cig without nicotine (E-cig Nic-; n = 28) or standard cigarette smoke (n = 27). Old F344 rats (25 months old, both sexes) were randomized into 2 groups: (1) 26 rats in the purified air (negative control) group and (2) 17 rats in the electronic cigarette vapor plus nicotine group (E-cig Nic+). After 12 weeks of exposure, hemodynamics were determined by Millar catheter, echocardiography, and thermodilution catheter, a few days after their last exposure.
Results
In young rats, cigarette smoke was associated with higher systolic, diastolic and mean blood pressures and peak LV systolic pressure, compared to air or E-cig Nic + or E-cig Nic- groups. Neither fractional shortening nor cardiac output differed among the groups. dp/dt min, a measure of diastolic LV function, was lowest in the E-cig Nic- group. Tau, a measure of LV relaxation was worse in this group as well. In old rats, E-cig vaping did not change heart rate, blood pressure, and cardiac function. However, E-cig Nic + exposure was associated with a greater heart weight/BW and LV weight/BW compared to air exposure in old rats, while this phenomenon was not observed in young rats.
Conclusions
Because E-cig vaping did not cause an increase in blood pressure and heart rate, or changed cardiac function compared to air in young rats after 12 weeks of exposure, while standard cigarette smoking was associated with an increase in blood pressure, our data agreeing with the statement that E-cig vaping was less harmful than cigarette smoking. E-cig vaping was associated with a greater heart weight/BW and LV weight/BW compared to air exposure in old rats, but this result was not observed in young rats, suggested that older animals might be more vulnerable to E-cig stimulus than younger ones.
Optimization of Distribution Network Reconfiguration for Power Loss Minimization Using GOA and PSO: A Case Study of Dilla Substation, Ethiopia
Authors: BalaKumar S. , Fetu Mohammed , mulugeta Baye
Published: September 2024

This paper presents a study that considers reconfiguring a given substation's distribution network at Dilla, Ethiopia, to minimize losses with the help of the Grasshopper Optimization Algorithm and Particle Swarm Optimization. The main aim is to achieve the best switch combination to minimize power loss, subject to system-imposed constraints. A mathematical model was carried out of the best network configuration at the Dilla feeder, inspired by grasshopper behavior. The proposed method was tested over a 76-bus radial distribution system at the Dilla substation. Compared with PSO and other existing methods, the performance of GOA is far better in reducing active and reactive power losses. The reduction of power loss with the help of GOA comes to be 70.3%, while with PSO, it comes out to be 68.8%. The voltage profile improved reasonably, stabilizing around one pu for all the buses. The results illustrated that GOA could be an effective and practical strategy for optimizing the distribution networks with increased reliability and decreased power losses. The paper concludes with a comparative analysis of the proposed GOA and existing methods for distribution network reconfiguration (DNR), showing that the GOA is more effective in reducing voltage deviation (VD) and power losses in the system.
Effects of Short-Term High and Low-Temperatures stress on Spodoptera litura (Fabricius) Eggs and Pupae Development and offspring
Authors: Tian Xu , Li Jinmeng , Wang Hancheng , Wang Qing , Zhang Xinghong , Sun Zhirong , Yang Yuting , Meng Jianyu , Shi Caihua
Published: September 2024

To clarify the effects of short-term high and low temperature treatment on the growth and development of Spodoptera litura (Fabricius) in eggs and pupae. S. litura eggs and pupae were treated at 35°C and 4°C for different time, respectively. The results demonstrated a gradual prolongation of the developmental period of S. litura eggs with increasing treatment time at a high temperature of 35°C for 6, 12, 18, 24, and 36 hours. Moreover, the hatching rate progressively decreased to as low as 19.33%, and no survival was observed after treating the eggs for 36 hours. Similarly, exposure to 4°C for durations of 24, 48, and 96 hours resulted in an extended developmental period accompanied by a gradual decline in the hatching rate. When subjected to 35°C at durations of 24, 48, and 96 hours, the emergence rates of female and male pupae decreased to 21.60-81.67% and 11.67-80%, respectively. The duration of high-temperature treatment initially shortened and then lengthened both the developmental period and preoviposition period; however, it led to a gradual reduction in oviposition time. After 48 hours of treatment, the shortest oviposition time recorded was 4.42 days. Nevertheless, a significant impact on oviposition behavior occurred after subjecting individuals to 35°C for 96 hours, resulting in minimal adult survival and no oviposition activity. Adult lifespan gradually decreased. In summary, short-term exposure to low temperatures at 4°C or high temperatures at 35°C had a inhibitory effect on the development and breeding of S.litura eggs and pupae.
Application of solid-state joining to investigate the Bi-polymer (PEHD-PP) joints performance
Authors: Serier Mohamed , Milad Abdalrhman. , Albaijan Ibrahim
Published: September 2024

Over the past ten years, the use of polymer products has taken a huge step forward in all sectors. The multiple properties of polymer types are positive factors that increase their scope of use in all aspects of daily life. Obtaining an ideal product requires assembling the polymers as needed. Friction welding is considered the safest way to connect polymer parts without any additional means. Welding two parts of the same polymer depends on controlling the effective factors in this process, which are the rotation speed, the feed, the penetration force, and the residence time of the spot weld. In this article, pneumatic energy is used to weld HDPE to PP by friction stir (linear and point) by selecting the ideal welding agents that meet the mixture of these two types of polymers and respond to pneumatic energy. The response surface method (RSM) and analysis of variance (ANOVA) were used to analyze the thermal results. The tensile test also has a role in deducing the mechanical properties of the welded area resulting from the mixture of these two types of polymers.
Injury Risk and Influencing Factors of Substance Use and Problematic Internet Use Among Emerging Adults in Beijing, China.
Authors: Zhou Xiaoding , Li Ruyu , Gao Qi , Wang xiaonan , Cheng Peixia , Zhu Huiping
Published: September 2024

Background
This study aimed to explore the impact of substance use (SU), problematic internet use (PIU), and their comorbidity on unintentional and intentional injuries among emerging adults in Beijing.
Methods
This cross-sectional study targeted emerging adults from two universities (undergraduates and postgraduates) in Beijing to ensure comprehension ability and voluntary participation. Commencing in July 2023, an on-site survey employed an anonymous electronic questionnaire accessible through a QR code. Descriptive measures, analysis of variance (ANOVA), chi-square tests, and logistic regression were used for statistical analysis. Logistic regression analyses were used to explore the risk of injury in different populations and to further analyze the factors influencing injury in different populations.
Results
Among the 1629 participants, substance use was categorized into 1045 low-risk (64.15%), 525 medium-risk (32.22%), and 59 (3.62%) high-risk users. For problematic internet use, participants were divided into non-PIU (n = 777, 47.70%), mild-moderate PIU (n = 819, 50.28%), and severe PIU (n = 33, 2.02%) groups. The comorbid group had a significantly greater risk of intentional injuries, with an adjusted odds ratio (aOR) of 2.08 (95% CI: 1.44–3.01). Patients in the comorbid group demonstrated increased risks of non-suicidal self-injury (NSSI) and suicidal ideation. The comorbid group had the highest risk for NSSI (aOR = 6.75, 95% CI = 3.15–14.48) and suicidal ideation (aOR = 3.49, 95% CI = 2.54–4.81). The demographic, psychological and social factors associated with injury risk varied among substance use, problematic internet use, and comorbid groups.
Conclusion
This study unveiled the prevalence of substance use and problematic internet use, each manifesting distinct risk profiles, among individuals in the emerging adulthood stage. Both substance use and problematic internet use independently contributed to increased risks of non-suicidal self-injury and suicidal ideation. Notably, the comorbid group faced the highest vulnerability, emphasizing the compounding effect of these behaviors. Improving the mental health of young people, the quality of their sleep, appropriate stress release and the control of bullying in schools may play a significant role in the occurrence of intentional injuries. Furthermore, it is even more important to intervene with emerging adulthood who are younger, live in urban areas, have neurotic personalities and female groups.
The Petunia heavy metal P-type ATPase PhHMA5II1 interacts with copper chaperons and regulate Cu detoxification
Authors: Pan Liru , Li Ruiling , Wu Jinglei , Li Yanbang
Published: September 2024

Copper (Cu) is an essential element for plant growth but toxic when present in excess. In this study we present the functional characterization of a petunia (Petunia hybrid) P1B-type heavy-metal ATPases (HMAs), PhHMA5II1. Heterologous expression of PhHMA5II1 in yeast (Saccharomyces cerevisiae) showed Cu transport activity. The expression of PhHMA5II1 in roots and shoots was unaffected by excess Cu. CRISPR/Cas9-edited mutant lines and PhHMA5II1 overexpressing transgenic plants were generated to investigate the functions of PhHMA5II1 in petunia. The PhHMA5II1 knockout mutant was hypersensitive to excess Cu and accumulated more Cu in roots compared to wild-type petunia. Overexpression of PhHMA5II1 enhanced Cu tolerance and reduced Cu accumulation in roots. Furthermore, PhHMA5II1 localized in endoplasmic reticulum, and the localization was unaffected by excess Cu. Yeast two-hybrid experiments and bimolecular fluorescence complementation assays demonstrate that PhHMA5II1 interact with petunia copper chaperons, PhATX1 and PhCCH. Finally, RNA-sequencing revealed that knockout PhHMA5II1 affected the expression of genes involved in cell wall organization, copper ion homeostasis, and response to oxidative stress. Taken together, PhHMA5II1 plays an important role in Cu detoxification in petunia.
Do the Regional Upper GI Bleed Services can provide safe and effective services? (Outcome based analysis from a regional upper GI bleeding service centre in the United Kingdom)
Authors: Anarajula Chaitthanya , Baskar Sangeetha , Schembri John , Nair Abhinav , Bhagrav Srishti , Nishad Nilanga , Thoufeeq Mo
Published: September 2024

Background
The aim of this study was to compare the clinical characteristics and clinical outcomes of patients who presented with AUGIB among two groups of patients who were transferred from local and district hospitals for endoscopy and subsequent management versus direct admissions to the emergency department with acute UGIB to the Sheffield University Hospital NHS Trust.
Methods
We included 259 patients who underwent upper GI endoscopy from April 2018 to March 2022, of whom 29 were transferred and 230 were direct admissions. The analysis focused on demographics, pathological findings, and time to endoscopy, blood transfusions, and hospital stay.
Results
Transferred patients were younger (median age 58 vs. 67 years) and received early endoscopic interventions compared to direct admissions (mean time to endoscopy 0.97 vs 2.1 days/p = 0.001). The means (s.d.) of hospital stay among the transferred and direct admission groups were 9.9 (9.5) and 8.3 (9.7) days, respectively (p = 0.43), regardless of intervention timing or transfusion needs. The timing of the procedure did not influence the length of hospital stay from the time of endoscopy to discharge (p = 0.241). Thirty-day mortality was 8 (28%) in the transferred group and 20 (9%) in the non-transferred group. (p = 0.006)
Conclusion
These findings underscore that regional bleeding services are safe and effective.
Single-Cell RNA Sequencing of the Carotid Artery and Femoral Artery of Rats Exposed to Hindlimb Unloading
Authors: Li Chengfei , Pan Yikai , Wang Yuan , Li Xi , Tie Yateng , Li Shuhan , Wang Ruonan , Zhao Xingcheng , Fan Jieyi , Yan Xianchun , Wang Yongchun , Sun Xiqing
Published: September 2024

Background
Prolonged spaceflight is known to cause vascular deconditioning and remodeling. Although tail suspension, a widely used spaceflight analog, is reported to result in vascular remodeling of rats, little is known about the cellular atlas of the heterogeneous cells of CA and FA from hindlimb-unloaded rats.
Methods
Firstly, we leveraged scRNA-seq to perform clustering analysis to identify diverse cell populations and sub-clusters within CA and FA from rats subjected to 3 months of hindlimb unloading, unravel dysregulated genes specific for artery types and cell types in HU group compared to Con. Then R package “Cellchat” was used to reveal ligand-receptor cellular communication. At last, the TF network analysis was performed using the SCENIC R package to predict the pivotal TFs in rat artery remodeling induced by hindlimb unloading.
Results
Clustering analysis identified ECs, SMCs, fibroblasts, and a spectrum of immune cells, as well as neuronal and stem cells. Notably, an increased percentage of ECs in the CA and a diminished proportion of SMCs in both CA and FA were observed following tail suspension. Intersection of dysregulated genes specific for artery type and cell type after tail suspension revealed several gene sets involved in ECM remodeling, inflammation, vasoconstriction, etc. Fibroblasts, in particular, exhibited the most significant gene expression variability, highlighting their plasticity. Subclustering within ECs, SMCs and fibroblasts revealed specialized subsets engaged in processes such as EndoMT and cell cycle checkpoint regulation. Additionally, enhanced intercellular interactions among major cell types, especially between SMC and fibroblast, underscored the importance of cell communication in vascular remodeling. Several TFs were identified as potentially influential in the vascular remodeling process under simulated microgravity conditions.
Conclusions
This study presents the first cellular atlas of the conductive arteries in hindlimb-unloaded rats, revealing a spectrum of dysregulated gene profiles. The identification of the subclusters of ECs, SMCs and fibroblasts, cellular communication analysis and transcription factors prediction are also included in this work. The findings provide a reference for future research on vascular deconditioning following long-duration spaceflight.
Geochemical formatives and risk assessment of heavy metals in the near-shore sediments of the Red Sea, Egypt
Authors: Dar Mahmoud A. Radi , Madkour Amany G. , Algendy Ahmed R. , Zaghloul Ghada Y. , Daba Abd El Mohsen S. El
Published: September 2024

The Red Sea's near-shore zones were thought to be nurseries and grazing grounds for the various economic fish species. To illustrate the relation between human health and seafloor sediments, the geological and geochemical properties of seafloor sediments were investigated in near-shore zones at each of Mersa Alam and Hurghada cities along the Red Sea. The obtained data illustrated that the sediment nature at Hurghada is primarily of biogenic origin, as indicated by the high carbonate contents; however, the sediment nature at Mersa Alam is attributed mainly to the terrigenous origin. Accordingly, the studied heavy metals at both localities showed different feeding sources; Mersa Alam sites showed high levels of; Fe, Mn, Zn, Ni, and Cu attributed to terrigenous inputs; however the high averages of Cd and Pb at Hurghada pointed accusingly to land-based and human activities. Geochemically and as indicated by the statistical parameters; Correlation coefficient, PCA and Geo-accumulation (Igeo); Mn, Zn, Cu and Ni were found mainly in association with Fe in the same source of accumulation and similar geochemical forms. However, the adsorption over sediment particles and/or assimilation inside the carbonate lattices are possible occurrences of Cd, Pb, and partially Ni. The calculated risk assessment parameters and Carcinogenic Risk (ILCR) don’t show any threats for marine organisms and humans consumption.