bluuebunny/crossref_metadata_2025 huggingface dataset:
Examining the effectiveness of telemonitoring with routinely acquired blood pressure data in primary care: challenges in the statistical analysis
Authors: Parker Richard , Padfield Paul , Hanley Janet , Pinnock Hilary , Kennedy John , Stoddart Andrew , Hammersley Vicky , Sheikh Aziz , McKinstry Brian
Published: January 2021

Background Scale-up BP was a quasi-experimental implementation study, following a successful randomised controlled trial of the roll-out of telemonitoring in primary care across Lothian, Scotland. Our primary objective was to assess the effect of telemonitoring on blood pressure (BP) control using routinely collected data. Telemonitored systolic and diastolic BP were compared with surgery BP measurements from patients not using telemonitoring (comparator patients). The statistical analysis and interpretation of findings was challenging due to the broad range of biases potentially influencing the results, including differences in the frequency of readings, ‘white coat effect’, end digit preference, and missing data. Methods Four different statistical methods were employed in order to minimise the impact of these biases on the comparison between telemonitoring and comparator groups. These methods were “standardisation with stratification”, “standardisation with matching”, “regression adjustment for propensity score” and “random coefficient modelling”. The first three methods standardised the groups so that all participants provided exactly two measurements at baseline and 6-12 months follow-up prior to analysis. . The fourth analysis used linear mixed modelling based on all available data. Results The standardisation with stratification analysis showed a significantly lower systolic BP in telemonitoring patients at 6-12 months follow-up (-3.42, 95% CI -1.72 to -5.11, p<0.001). For the standardisation with matching and regression adjustment for propensity score analyses systolic BP was also significantly lower (-5.96, 95% CI -3.55 to -8.36, p<0.001) and (-3.73, -5.34 to -2.13, p<0.001) respectively, even after assuming that -5 of the difference was due to ‘white coat effect’. For the random coefficient modelling, the improvement in systolic BP was estimated to be -4.68 (95% CI -3.12 to -6.24, p<0.001) after one year.Conclusions The four analyses provide additional evidence for the effectiveness of telemonitoring in controlling BP in routine primary care. The random coefficient analysis is particularly recommended due to its ability to utilise all available data. However, adjusting for the complex array of biases was difficult. Researchers should appreciate the potential for bias in implementation studies and seek to acquire a detailed understanding of the study context in order to design appropriate analytical approaches.
Repetitive Overseeding for Ecological Management of Grass Playing Fields
Authors: Gannett Maria , Bray Natalie , Lampman Joellen , Lerner Jennifer , Murray Kathy , Wallace Victoria , Yeh Tamson , Slavens Mark , Thompson Grant L. , Kao-Kniffin Jenny
Published: January 2021

Because of public concern about exposing children to pesticides, legislation restricting its use on school playing fields has increased. One way to manage weeds without chemical herbicides is overseeding or the practice of repetitively seeding with a rapidly germinating turfgrass species. Overseeding for broadleaf weed control was tested on eight fields in Central New York (CNY) for three seasons and 40 fields across the northeastern United States for two seasons. Half of each field was treated each season by overseeding Lolium perenne L. (perennial ryegrass) three to five times each season for a total of 731 kg seed/ha (15 lb per 1000 ft2). Changes in the percent broadleaf weeds, grass, bare ground, soil moisture, Dark Green Color Index (DGCI) of grass cover, depth to soil compaction, and shear strength were measured after each treatment. The percent broadleaf weeds decreased and the percent grass cover increased due to overseeding in the Northeast fields, but not in CNY fields. Depth to compaction, percent soil moisture, and shear strength varied over time in the Northeast fields, and the percent bare ground, DGCI, and soil moisture varied over time in CNY fields. DGCI in the Northeast and soil compaction in CNY were affected by the interaction of overseeding × time. Although overseeding can be a beneficial weed management tool and affect other turf and soil traits in an integrated turf management program, monitoring environmental conditions and supporting field maintenance routines are critical weed management strategies for maintaining healthy turfgrass.
A two-way linear piezoelectric vibratory conveyor actuated by a composite sinusoidal voltage input
Authors: Lee Chun-Ying , Teng Tsung-An , Hu Chun-Ming
Published: January 2021

Piezoelectric vibratory conveyors are widely used in many industrial fields such as factory automation. However, there is still a limitation for most cases that the vibratory conveyor can only feed in the designed direction. In today's multitasking intelligent machinery, how to sort different parts from the same feed source and convey them efficiently in different directions remains a challenge to be overcome. This study proposes an innovative design that uses a composite sinusoidal control signal to drive a linear two-stage piezoelectric vibratory feeder. By simply tuning the amplitude and phase of the input composite signal, the conveying velocity and direction can be altered easily. The dynamic characteristics of this feeder were both investigated by theoretical formulation and experimental measurement. It is found that the conveying performance of this feeder is better suited for using the composite signal with two sinusoidal components of double frequency. With the composite control signal synthesized by two sinusoidal components of 237.5 Hz and 475.0 Hz, which were close to the feeder’s first two resonance frequencies to increase the response gain of the structure, and the input voltage of 60 V, which corresponded to the trough’s displacement amplitude of 54.5 m, the measured conveying speeds were +30.8 mm/s and –33.3 mm/s for setting the phase angles 180° and 0°, respectively. The result demonstrates the feasibility of the proposed two-way vibratory feeder design.
Music venues in transition: States of autonomy, dependence and subcultural institutionalization
Authors: Kuchar Robin
Published: January 2021

: Taking into account changing spatial structures of local music scenes and processes of music production, urban regeneration, and the commercialization of live music during the last decades, this article examines how ongoing transformations of socio-spatial environments exert influence on originally do-it-yourself music venues as a specific kind of urban music space. Venues are understood as individual actors that develop in relation to their initial spatial and cultural strategies. Therefore, the status of these venues reaches from traditionalist but highly dependent to paradoxical forms of “subcultural institutionalization”. Based on empirical data from three case studies in Hamburg, Germany, fieldwork shows that DIY-driven clubs increasingly become hijacked or taken-over spaces that apply different strategies in order to preserve their idea(l)s of self-governed and collective cultural work.
Digital Tools to Support Family-Based Weight Management for Children: Mixed Methods Pilot and Feasibility Study (Preprint)
Authors: Staiano Amanda E , Shanley Jenelle R , Kihm Holly , Hawkins Keely R , Self-Brown Shannon , Hӧchsmann Christoph , Osborne Melissa C , LeBlanc Monique M , Apolzan John W , Martin Corby K
Published: January 2021

BACKGROUND

Family-based behavioral therapy is an efficacious approach to deliver weight management counseling to children and their parents. However, most families do not have access to in-person, evidence-based treatment. We previously developed and tested DRIVE (Developing Relationships that Include Values of Eating and Exercise), a home-based parent training program to maintain body weight among children at risk for obesity, with the intent to eventually disseminate it nationally alongside SafeCare, a parent support program that focuses on parent-child interactions. Currently the DRIVE program has only been tested independently of SafeCare. This study created the “mHealth DRIVE” program by further adapting DRIVE to incorporate digital and mobile health tools, including remotely delivered sessions, a wireless scale that enabled a child-tailored weight graph, and a pedometer. Telehealth delivery via mHealth platforms and other digital tools can improve program cost-effectiveness, deliver long-term care, and directly support both families and care providers.

OBJECTIVE

The objective of this study was to examine preliminary acceptability and effectiveness of the mHealth DRIVE program among children and parents who received it and among SafeCare providers who potentially could deliver it.

METHODS

Study 1 was a 13-week pilot study of a remotely delivered mHealth family-based weight management program. Satisfaction surveys were administered, and height and weight were measured pre- and post-study. Study 2 was a feasibility/acceptability survey administered to SafeCare providers.

RESULTS

Parental and child satisfaction (mean of 4.9/6.0 and 3.8/5.0, respectively) were high, and children’s (N=10) BMI z-scores significantly decreased (mean –0.14, SD 0.17; P=.025). Over 90% of SafeCare providers (N=74) indicated that SafeCare families would benefit from learning how to eat healthily and be more active, and 80% of providers reported that they and the families would benefit from digital tools to support child weight management.

CONCLUSIONS

Pediatric mHealth weight management interventions show promise for effectiveness and acceptability by families and providers.

CLINICALTRIAL

Clinicaltrials.gov NCT03297541, https://clinicaltrials.gov/ct2/show/NCT03297541.
Exploring Test-Retest Reliability and Longitudinal Stability of Digital Biomarkers for Parkinson Disease in the m-Power Data Set: Cohort Study (Preprint)
Authors: Sahandi Far Mehran , Eickhoff Simon B , Goni Maria , Dukart Juergen
Published: January 2021

BACKGROUND

Digital biomarkers (DB), as captured using sensors embedded in modern smart devices, are a promising technology for home-based sign and symptom monitoring in Parkinson disease (PD).

OBJECTIVE

Despite extensive application in recent studies, test-retest reliability and longitudinal stability of DB have not been well addressed in this context. We utilized the large-scale m-Power data set to establish the test-retest reliability and longitudinal stability of gait, balance, voice, and tapping tasks in an unsupervised and self-administered daily life setting in patients with PD and healthy controls (HC).

METHODS

Intraclass correlation coefficients were computed to estimate the test-retest reliability of features that also differentiate between patients with PD and healthy volunteers. In addition, we tested for longitudinal stability of DB measures in PD and HC, as well as for their sensitivity to PD medication effects.

RESULTS

Among the features differing between PD and HC, only a few tapping and voice features had good to excellent test-retest reliabilities and medium to large effect sizes. All other features performed poorly in this respect. Only a few features were sensitive to medication effects. The longitudinal analyses revealed significant alterations over time across a variety of features and in particular for the tapping task.

CONCLUSIONS

These results indicate the need for further development of more standardized, sensitive, and reliable DB for application in self-administered remote studies in patients with PD. Motivational, learning, and other confounders may cause variations in performance that need to be considered in DB longitudinal applications.
Problematic Degrading Music Lyrics and Teen pregnancy during COVID-19 in Rwanda: A policy maker concern? (Preprint)
Authors: Ngamije James
Published: January 2021

UNSTRUCTURED

Lockdown and school closure for long term related to the coronavirus (COVID-19) pandemic have led to greatly participation in music. Many Rwandan artists support government in its effort to fight against COVID-19 pandemic. However, for others it was an opportunity to produce degrading music lyrics. Although online music can be a healthy coping for the majority during COVID-19 lockdown and school closure, degrading music preferred by many youth, can also pose risks to early sexual behaviors contributing to existing risk factors for teen pregnancy such as economic, social and physical environmental determinants. In this paper, I outline my recommendations for research in this area, and prevention of music containing sex message to reduce early sexual behavior and teen pregnancy.
ClinicalTrials.gov as a Source of Information About Expanded Access Programs: Cohort Study (Preprint)
Authors: Borysowski Jan , Górski Andrzej
Published: January 2021

BACKGROUND

ClinicalTrials.gov (CT.gov) is the most comprehensive internet-based register of different types of clinical studies. Expanded access is the use of unapproved drugs, biologics, or medical devices outside of clinical trials. One of the key problems in expanded access is the availability to both health care providers and patients of information about unapproved treatments.

OBJECTIVE

We aimed to evaluate CT.gov as a potential source of information about expanded access programs.

METHODS

We assessed the completeness of information in the records of 228 expanded access programs registered with CT.gov from February 2017 through May 2020. Moreover, we examined what percentage of published expanded access studies has been registered with CT.gov. Logistic regression (univariate and multivariate) and mediation analyses were used to identify the predictors of the absence of some information and a study’s nonregistration.

RESULTS

We found that some important data were missing from the records of many programs. Information that was missing most often included a detailed study description, facility information, central contact person, and eligibility criteria (55.3%, 54.0%, 41.7%, and 17.5% of the programs, respectively). Multivariate analysis showed that information about central contact person was more likely to be missing from records of studies registered in 2017 (adjusted OR 21.93; 95% CI 4.42-172.29; P<.001). This finding was confirmed by mediation analysis (P=.02). Furthermore, 14% of the programs were registered retrospectively. We also showed that only 33 of 77 (42.9%) expanded access studies performed in the United States and published from 2014 through 2019 were registered with CT.gov. However, multivariate logistic regression analysis showed no significant association between any of the variables related to the studies and the odds of study nonregistration (P>.01).

CONCLUSIONS

Currently, CT.gov is a quite fragmentary source of data on expanded access programs. This problem is important because CT.gov is the only publicly available primary source of information about specific programs. We suggest the actions that should be taken by different stakeholders to fully exploit this register as a source of information about expanded access.
Constructing High-Fidelity Phenotype Knowledge Graphs for Infectious Diseases With a Fine-Grained Semantic Information Model: Development and Usability Study (Preprint)
Authors: Deng Lizong , Chen Luming , Yang Tao , Liu Mi , Li Shicheng , Jiang Taijiao
Published: January 2021

BACKGROUND

Phenotypes characterize the clinical manifestations of diseases and provide important information for diagnosis. Therefore, the construction of phenotype knowledge graphs for diseases is valuable to the development of artificial intelligence in medicine. However, phenotype knowledge graphs in current knowledge bases such as WikiData and DBpedia are coarse-grained knowledge graphs because they only consider the core concepts of phenotypes while neglecting the details (attributes) associated with these phenotypes.

OBJECTIVE

To characterize the details of disease phenotypes for clinical guidelines, we proposed a fine-grained semantic information model named PhenoSSU (semantic structured unit of phenotypes).

METHODS

PhenoSSU is an “entity-attribute-value” model by its very nature, and it aims to capture the full semantic information underlying phenotype descriptions with a series of attributes and values. A total of 193 clinical guidelines for infectious diseases from Wikipedia were selected as the study corpus, and 12 attributes from SNOMED-CT were introduced into the PhenoSSU model based on the co-occurrences of phenotype concepts and attribute values. The expressive power of the PhenoSSU model was evaluated by analyzing whether PhenoSSU instances could capture the full semantics underlying the descriptions of the corresponding phenotypes. To automatically construct fine-grained phenotype knowledge graphs, a hybrid strategy that first recognized phenotype concepts with the MetaMap tool and then predicted the attribute values of phenotypes with machine learning classifiers was developed.

RESULTS

Fine-grained phenotype knowledge graphs of 193 infectious diseases were manually constructed with the BRAT annotation tool. A total of 4020 PhenoSSU instances were annotated in these knowledge graphs, and 3757 of them (89.5%) were found to be able to capture the full semantics underlying the descriptions of the corresponding phenotypes listed in clinical guidelines. By comparison, other information models, such as the clinical element model and the HL7 fast health care interoperability resource model, could only capture the full semantics underlying 48.4% (2034/4020) and 21.8% (914/4020) of the descriptions of phenotypes listed in clinical guidelines, respectively. The hybrid strategy achieved an F1-score of 0.732 for the subtask of phenotype concept recognition and an average weighted accuracy of 0.776 for the subtask of attribute value prediction.

CONCLUSIONS

PhenoSSU is an effective information model for the precise representation of phenotype knowledge for clinical guidelines, and machine learning can be used to improve the efficiency of constructing PhenoSSU-based knowledge graphs. Our work will potentially shift the focus of medical knowledge engineering from a coarse-grained level to a more fine-grained level.
Improving the Prognosis of Pancreatic Cancer Through Early Detection: Protocol for a Prospective Observational Study (Preprint)
Authors: Yamada Reiko , Isaji Shuji , Fujii Takehiro , Mizuno Shugo , Kishiwada Masashi , Murata Yasuhiro , Hayasaki Aoi , Inoue Hiroyuki , Umeda Yuhei , Tanaka Kyosuke , Hamada Yasuhiko , Tsuboi Junya , Kato Toshio , Kondo Yoshihiro , Matsuda Shinsuke , Watanabe Noriko , Ogura Toru , Tamaru Satoshi
Published: January 2021

BACKGROUND

Pancreatic cancer is associated with high mortality and its rates of detection are very low; as such, the disease is typically diagnosed at an advanced stage. A number of risk factors for pancreatic cancer have been reported and may be used to identify individuals at high risk for the development of this disease.

OBJECTIVE

The aim of this prospective, observational trial is to evaluate a scoring metric for systematic early detection of pancreatic cancer in Mie Prefecture, Japan.

METHODS

Eligible patients aged 20 years and older will be referred from participating clinics in the Tsu City area to the Faculty of Medicine, Gastroenterology, and Hepatology at Mie University Graduate School, until September 30, 2022. Participants will undergo a detailed examination for pancreatic cancer. Data collection will include diagnostic and follow-up imaging data and disease staging information.

RESULTS

The study was initiated in September 2020 and aims to recruit at least 150 patients in a 2-year period. Recruitment of patients is currently still underway. Final data analysis is expected to be complete by March 2025.

CONCLUSIONS

This study will provide insights into the feasibility of using a scoring system for the early detection of pancreatic cancer, thus potentially improving the survival outcomes of diagnosed patients.

CLINICALTRIAL

UMIN-CTR Clinical Trials Registry UMIN000041624; https://tinyurl.com/94tbbn3s

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/26898
Kuwaiti Hospital Patients’ Continuance Intention to Use Telemedical Systems in the Wake of the COVID-19 Pandemic: Survey Study Among Patients (Preprint)
Authors: Almutairi Ibtesam
Published: January 2021

BACKGROUND

Telemedicine is a system using telecommunication technologies to diagnose, treat, and monitor patients by healthcare physicians and specialists in many developing countries such as Kuwait. Telemedicine services have proven to be successful in reporting and tracking patient records, delivering, real time monitoring, providing correct medications, and early detection of clinical decline. Covid-19 pandemic period have reinforced telemedicine system’s benefits even more in Kuwait.

OBJECTIVE

The objective of this study is to investigate factors influencing patients’ continuance intention to use telemedicine after the COVID-19 pandemic in the medical sector of Kuwait.

METHODS

The updated Delone and Maclean (2003) model was utilized to investigate the aforementioned factors. As such, this research applied quantitative research methods with a sample of 290 participants from patients in Dar Al Shifa Hospital, a private hospital in Kuwait which utilizes telemedical services called ‘Sehaty online’. The corresponding data was analyzed using SmartPLS.

RESULTS

The findings of this study revealed that the relationship of both telemedicine’s information quality and system quality with patient’s satisfaction are significant with (β = 0.377, t = 5.612, P < 0.001), (β = 0.295, t = 4.397, P < 0.001) respectively. While the relationship of service quality and patient’s satisfaction is not significant with (β = -0.056, t = 0.894, P > 0.05). patient’s satisfaction relationship with patients’ continuance intention to use telemedicine found to be significant with (β = 0.403, t = 8.732, P < 0.001).

CONCLUSIONS

It has been concluded that information quality and system quality have a positive and significant influence on patient’s satisfaction, whereas service quality has an insignificant influence on patient’s satisfaction. Also, patients’ continuance intention to use telemedicine is found to be significantly impacted by their satisfaction.
Financial Development and Economic Growth: Evidence from the Eurozone
Authors: Stamatiou Pavlos , Papadopoulou Maria
Published: January 2021

The aim of this paper is to investigate the relationship between financial development and economic growth, within a panel framework that also accounts for trade openness, for the case of Eurozone using data covering the period 1990-2018. We explore this relationship using panel analysis techniques, robust to cross sectional dependence, in order to investigate the presence of causality between the variables. The cointegration results suggested that there is one cointegrated vector between the functions of economic growth, financial development and trade openness. In addition, the causality results of the study revealed, both in the short and long-run, that there is a unidirectional causal relationship between financial development and economic growth with direction from economic growth to financial development, as well as a unidirectional causality running from trade openness to financial development.
JOGOS DIGITAIS E SUAS POSSIBILIDADES NA/PARA EDUCAÇÃO INCLUSIVA
Authors: Rocha Julimar Santiago , Correia Patrícia Carla da Hora , Santos Jocenildes Zacarias
Published: January 2021

RESUMO
As transformações culturais e a evolução das novas tecnologias da comunicação e informação, associadas à diversidade dos sujeitos na escola da contemporaneidade, trazem desafios relacionados às práticas de ensino que precisam romper com o modelo tradicional para construção do conhecimento. Ao repensar as metodologias, surge a perspectiva do uso de jogos digitais para promoção da aprendizagem, principalmente para o público-alvo da educação inclusiva. O objetivo dessa pesquisa bibliográfica é refletir sobre as possibilidades dos jogos digitais na/para a educação inclusiva, analisando produções acadêmicas de seis universidades públicas brasileiras (2009-2019). A busca foi realizada na Biblioteca Digital Brasileira de Teses e Dissertações (BDTD). Através de diferentes jogos e em interlocução com diferentes campos de conhecimento, os pesquisadores propõem uma nova forma de ensinar, de aprender, de interagir com o mundo virtual, acreditando que todos os sujeitos são capazes de aprender.
A PARTICIPAÇÃO DA CRIANÇA NA PESQUISA: entre possibilidades e limites
Authors: Brostolin Marta Regina , Zaikievicz Azevedo Ana Paula
Published: January 2021

Este texto, recorte de uma pesquisa de Mestrado, tece reflexões acerca da participação de crianças em pesquisa. A intenção não é analisar os resultados da pesquisa realizada, mas sim refletir acerca das possibilidades e limites que a pesquisa com crianças nos impõe como processo investigativo denso que necessita de muito estudo, planejamento, organização e ética. A pesquisa ancora-se na Sociologia da Infância, pois esse campo teórico defende as crianças enquanto sujeitos de direitos, produtores de culturas e de saberes, que precisam ser escutadas e respeitadas. Com o desenvolvimento da pesquisa foi possível constatar que o exercício de pesquisar com criança não é um processo simples, mas um exercício que exige, cuidado, sensibilidade, ética, flexibilidade e amplo conhecimento sobre a infância por parte do pesquisador, pois, envolver as crianças na pesquisa, torna-se um importante mecanismo de reconhecimento destas enquanto autores e atores de suas próprias histórias que merecem ser escutadas e respeitados pelas suas singularidades.
POSSIBILIDADES NA FORMAÇÃO DE CONCEITOS POR CRIANÇAS COM SÍNDROME DE DOWN NA ESCOLA COMUM
Authors: Couto Pimentel Susana
Published: January 2021

Esta pesquisa, realizada com apoio da FAPESB, objetivou analisar o processo de apropriação de conceitos por estudante com Síndrome de Down (SD) inserida no segundo ano do Ensino Fundamental de uma escola comum. A metodologia utilizada foi a análise microgenética dos momentos de trabalho docente com conceitos na área de Ciências. A análise microgenética direciona o olhar do observador para o processo de internalização que ocorre a partir da mediação social. Os resultados apontam para a importância de mediações pedagógicas que favoreçam situações vivenciais, apoiadas nos conceitos cotidianos, para apropriação dos conceitos científicos, bem como para elaboração de estratégias de memorização. Conclui-se que o professor deve proporcionar atividades que favoreçam o avanço da criança com SD na internalização do pensamento conceitual, de modo a organizar suas percepções iniciais, vagas e sincréticas, em modos mais ordenados do pensamento que dão significado à experiência concreta.
La productividad de los puertos en la región del APEC: un estudio a través del análisis de la frontera estocástica
Authors: Delfín Ortega Odette Virginia , Navarro Chávez José César Lenin
Published: January 2021

Esta investigación tiene como objetivo determinar la Productividad Total de los Factores (PTF) de los 40 principales puertos de la región del APEC durante el periodo 2005-2015. Se mide la PTF a partir de sus componentes: cambio tecnológico, cambio en la eficiencia técnica y cambio en la eficiencia de escala, instrumentando el Análisis de la Frontera Estocástica (SFA). Se tiene como variable dependiente el número de teus y como variables independientes la longitud del muelle y el personal ocupado. En promedio los puertos del APEC tuvieron un incremento en su PTF del 5.10% durante los años de estudio, donde el aumento en la eficiencia de escala es quien más incidencia tiene con un 4%.
Energy consumption and atmospheric emissions from refined petroleum in Mexico by 2030
Authors: Granados Hernández Elías , López  Andrade Xicoténcatl , Vega Rangel Elizabeth , Sosa Echeverria Rodolfo , Alarcón Jiménez Ana Luisa , Fuentes García Gilberto , Sánchez Álvarez Pablo
Published: January 2021

One of the basic needs for a country’s economic development is to cover the major fuel demand, and both energy consumption and environmental impacts resulting from the production of such fuels need to be fast and reliable. The purpose of this paper is to contribute to an estimate of energy consumption and atmospheric emissions of some of the pollutant species reported by Pemex Refinacion under different projections. The predictive estimate model was applied considering four different gasoline demand scenarios, as well as different refining technology options to satisfy fuel consumption needs, based on production yields: four different types of refineries, three types of crude oils and eight different processes. Emission estimates were determined applying emission factors, both for the type of fossil fuel energy source used in the direct heating processes for vapor generation, as well by using electric energy. Results show that the equivalent energy consumption relative to the total processes crude is greater in complex refineries (full conversion); however, a greater conversion efficiency allows a smaller volume of crude consumption needed to satisfy the fuel demand with lower emissions relative to other types of technologies. Mexico’s possible refineries need to adapt themselves to different operation scenarios, such as changes in the crude’s yield, the quality of the product, variations in the prices of the crude and of the refined products. Therefore, is important to develop and apply perspectives than maximize productivity and minimize energy consumption, reducing air emissions, in constant change scenarios. Finally, the problem would then be evaluating which would be more convenient to obtain a greater socio-economic benefit: reduce emissions to the atmosphere or to lower operation costs of the refinery.
Mejoramiento de terreno afectado por grietas para la cimentación de viviendas de mampostería
Authors: Sánchez Guzmán Jesús , Auvinet Guichard Gabriel
Published: January 2021

Este trabajo se refiere al problema del agrietamiento del suelo que afecta gran parte de la zona lacustre del valle de México. Por medio de simulaciones por el Método de Elementos Discretos se estudia el efecto de las grietas sobre el comportamiento de viviendas de mampostería. Específicamente, se consideran las grietas con escalón que se presentan en las zonas de transición entre suelos blandos y firmes de la ciudad. Los modelos reproducen en forma cualitativa los mecanismos de deformación y de fracturamiento que se observan típicamente en las viviendas afectadas. Se pone en evidencia que al incluir una caja disipadora de deformaciones constituida por material granular en la cimentación, los daños en las viviendas se reducen considerablemente. Además, se revisa el comportamiento de la cimentación de viviendas tipo a construir y se emiten algunas recomendaciones complementarias para el mejoramiento del terreno de cimentación.
IMPROVING INFORMATION LITERACY SKILLS AGAINST HOAX ON CORONA VIRUS IN SOCIAL MEDIA AMONG TEENAGERS IN BANDARLAMPUNG PENINGKATAN KETERAMPILAN INFORMATION LITERACY DALAM MELAWAN HOAX TENTANG VIRUS CORONA DI MEDIA SOSIAL BAGI REMAJA DI BANDARLAMPUNG
Authors: Sulistyarini Dhanik , Gustina Anna , Suciska Wulan , Ashaf Abdul Firman
Published: January 2021

ABSTRACTThe purpose of the community service activity was to improve knowledge and information literacy skills among teenagers in Bandarlampung against hoax on Corona virus in social media. The outbreak of the Corona virus (Covid-19) in the past few months has resulted in widely spread hoaxes and conspiracy theories in the community, including in social media. Indonesia is one of countries with the highest number of social media users in the world, and teenager is a social group that are very active in social media. It suggests that teenagers are vulnerable to hoaxes in social media. It is the reason that this training is very important for them. After participating in this activity, the teenagers became more aware that they need to more critical toward information in social media, they have more understanding about hoax characteristics, and they know how to evaluate information from social media.Keywords: media literacy, information literacy, social mediaABSTRAKTujuan dari kegiatan pengabdian kepada masyarakat ini adalah untuk meningkatkan pengetahuan dan keterampilan information literacy bagi para remaja dalam melawan hoax tentang virus Corona di media sosial. Merebaknya penyebaran virus Corona (Covid-19) beberapa bulan terakhir telah menyebabkan maraknya hoax dan teori konspirasi dalam masyarakat, termasuk di media sosial. Indonesia merupakan salah satu negara dengan jumlah pengguna media sosial yang tertinggi di dunia, dan remaja merupakan kelompok masyarakat yang sangat aktif di media sosial. Hal itu mengindikasikan bahwa remaja merupakan kelompok yang rentan terhadap hoax di media sosial. Oleh karena itu kegiatan ini sangat penting untuk mengedukasi remaja supaya dapat menangkal hoax di media sosial. Setelah mengikuti kegiatan ini, pengetahuan dan kemampuan para remaja meningkat dalam beberapa hal, antara lain sikap kritis terhadap informasi di media sosial, mereka lebih memahami ciri-ciri hoax, dan cara mengevaluasi informasi di media sosial.Kata kunci: literasi media, literasi informasi, media sosial.
The Majelis Tarjih Muhammadiyah’s Fatwa on the Pregnant Marriage: A Maqāṣid Approach
Authors: Mutmainah Nurul Afiyah Hikmatul
Published: January 2021

This study aims to analyse the Majelis Tarjih Muhammadiyah’s fatwa on the case of pregnant marriage applying the maqāṣid al-sharī’ah approach. There are three rationales why this research is important. First, this issue is considered controversial as opinions regarding the law of pregnant marriage among Islamic scholars are quite diverse. Second, Muhammadiyah as an Islamic organisation in the largest Muslim majority country (Indonesia) has a semi-authoritative body, namely the Majelis Tarjih Muhammadiyah; to provide religious views for its members. Third, this research is important to examine the council’s fatwa whether it is in accordance with maqāṣid al-sharī’ah. Based on the author’s analysis, it has been argued that the Majelis Tarjih Muhammadiyah’s fatwa on the law of pregnant marriage is in accordance with maqāṣid al-sharī’ah. This research also studies various opinions and methods used by Muhammadiyah. Finally, this research concludes that pregnant women should not be married except by men who cause pregnancy or by their ex-husbands.
El bandolerismo mexicano como respuesta al contexto socioeconómico porfirista (1877-1893)
Authors: Escalante Piña Pablo
Published: January 2021

En la presente investigación se aborda el bandolerismo mexicano en un periodo en el cual las circunstancias del contexto histórico fueron coyunturales para la presencia de dicha práctica social. Se plantea como idea central que efectivamente el bandolerismo mexicano fue una de las tantas respuestas al contexto socioeconómico entre 1877-1893. Para ello, en un primer momento se elabora un balance historiográfico a partir del inicio de la guerra de independencia hasta la década de 1870. Asimismo, se efectúa la caracterización de la región conocida como el Bajío michoacano, partiendo del supuesto de que el contexto socioeconómico pudo influir en los índices de presencia y permanencia del bandidaje. Finalmente, se realiza la identificación de las gavillas y bandidos que tuvieron lugar en el Estado de Michoacán entre 1877-1893, ello, para delimitar la morfología del bandidaje y la relación que guardaba con el contexto que se estaba viviendo en la sociedad mexicana.
Símbolos nacionales en cambio: el caso del estandarte real de Francisco Pizarro
Authors: Sánchez Paredes Libardo
Published: January 2021

Los símbolos sobre los cuales se cimenta el sentimiento nacional tienden a ser incuestionados. Se olvida que son productos de un proceso histórico de definición que incluye diversas interpretaciones y debates. El estandarte real atribuido a Francisco Pizarro que reposa en las colecciones del Museo Nacional de Colombia es un ejemplo paradigmático que permite apreciar las transformaciones de sentido en un objeto con el que se ha simbolizado tanto el poder real como la independencia nacional. El artículo indaga en torno a dichas transformaciones en la intención significante de este estandarte desde finales de la época colonial hasta inicios del siglo xx. El análisis muestra que el sentido del estandarte ha cambiado, obedeciendo a las tendencias ideológicas de las élites políticas en curso.
The Factors Affecting the Investors’ Decisions: A Study on Nuclear Energy Investments
Authors: Yüksel Serhat , Çağlayan Çağatay
Published: January 2021

The aim of this study is to evaluate the indicators affecting the decision of investors in nuclear energy sector within the scope of behavioral economics. There are two different stages in the analysis process in this paper. First, after a detailed literature review, six different behavioral economics biases are selected as the criteria. Secondly, these factors are weighted for the nuclear energy investors. For this purpose, fuzzy DEMATEL methodology is used. The findings indicate that uncertainty avoidance and overconfidence bias are the most essential factors affecting the decision of investors. Similarly, the mental accounting bias and regret avoidance also have important impacts for this situation. However, loss aversion bias and lack of self-control have the lowest weights for the nuclear energy investors. Additionally, with respect to the impact relation map, it is concluded that uncertainty avoidance is the most influencing issue whereas overconfidence bias is identified as the most influenced factor. Our results suggest that that strategies should be implemented to decrease the anxiety of the nuclear energy investments. For this purpose, governments should take some actions to minimize the uncertainty in the market. For instance, providing loans with low interest rate can minimize interest rate risk. This will probably decrease the anxiety of the nuclear energy investors.
Autologous fat grafting in the face and neck-Multinational trends and knowledge of the safety, applications and indications considering oncologic risk potential
Authors: Fiedler Lukas S , Saleh Daniel B , Mukrowsky Alicia
Published: January 2021

Introduction Autologous fat grafting (AFG) has both aesthetic and
reconstructive applications. Described by Neuber in 1893 there are
numerous applications of AFG as the body of evidence for its use
has expanded. The earliest controversies were evident in lipofilling for
breast defects post-oncological treatment, and to this day some
countries do not allow it for fear of inducing tumourogenesis in an
oncologically ablated field. Adipose-derived stem cells (ASCs) have been
shown pro-oncologic behaviour in xenografts, however, this has not been
reproduced in clinical observations thus far.

Material and Methods We sought to review contemporary harvesting
and processing techniques for AFG in the craniofacial region,
therefore distributed a survey to evaluate the opinion and clinical
impact of oncological risk across four European countries with possibly
differing clinical attitudes.

Results In the craniofacial region AFG is mostly used for
aesthetic indications, cannula hand-held aspiration and centrifugation
seem to be the predominant harvesting and processing techniques. Half of
our respondents tell patients about the possibility of pro-oncologic
behaviour of AFG. We found no significant geographical
differences between the German-speaking and the English groups
concerning their harvesting and processing technique. German
participants seem to perform AFG more often and mostly use it for
cosmetic and post-cancer treatment sequelae, English participants
homogenically use AFG for cosmetic reasons.

Conclusion Theoretical pro-oncologic behaviour of craniofacial
AFG does not deter surgeons. Perhaps, we shouldn’t consider
discussing this complex area of oncogenesis with patients as there is no
elevated risk from what we know.
Pleural tuberculosis in children and adolescents: a difficult diagnosis?
Authors: Lunelli Magda , Ferreira Isabel Cristina , Sarmento Muriel , Chakr Valentina , Fischer Gilberto
Published: January 2021

Objective This study aimed to describe the clinical and laboratory
findings of patients diagnosed with pleural tuberculosis (PT) at two
tertiary university hospitals in Southern Brazil. Methods Patients below
18 years of age admitted to the study hospitals were retrospectively
evaluated. Medical and epidemiological history, tuberculin skin test
(TST) results, radiological and pathological findings, and pleural fluid
(PF) analysis were retrieved from health records. Results Ninety-two
patients with PT were identified during the study period. Among them, 51
(55%) were males. The mean age was 10.9 years old. Twenty-one percent
was represented by children aged six years or less. The most common
symptoms were fever (88%), cough (72%) and chest pain (70%). The time
between the onset of symptoms and diagnosis varied between 2 and 300
days, with a median of 16 days. Unilateral pleural effusion was
described in 96% of the cases. Lymphocyte predominance was found in
90% of PF samples. The adenosine deaminase dosage of PF was greater
than 40 U/L in 85% of the patients. Prior diagnosis of community
acquired pneumonia and antibiotic use were observed in 76% of the
cases. Conclusion We suggest consider the diagnosis of PT in children
and adolescents with the following characteristics: fever, cough and
thoracic pain as presenting symptoms; history of contact with
tuberculosis; Mantoux test 10 mm; unilateral pleural effusion;
lymphocytes predominance in PF sample; pleural fluid ADA greater than 40
U/L and poor response to antibiotics prescribed for community-acquired
pneumonia.
Early Ambulatory Multidrug Therapy Reduces Hospitalization and Death in High-Risk Patients with SARS-CoV-2 (COVID-19)
Authors: Procter Brian , Ross Casey , Pickard Vaness , Smith Erica , Hanson Cortney , McCullough Peter A.
Published: January 2021

Background. There is an emergency need for early ambulatory treatment of
COVID-19 in acutely ill patients in an attempt to reduce disease
progression and the risks of hospitalization and death. Methods and
Results. We recently reported results on 320 high-risk (age
> 50 with ≥ 1 comorbidity) COVID-19 cases and have updated
our results with 549 additional cases in period ending December 16,
2020. Our protocol utilizes at least two agents with antiviral activity
against SARS-CoV-2 (zinc, hydroxychloroquine, ivermectin) and one
antibiotic (azithromycin, doxycycline, ceftriaxone) along with inhaled
budesonide and/or intramuscular dexamethasone. Albuterol nebulizer,
inhaled budesonide, intravenous volume expansion with supplemental
parenteral thiamine 500 mg, magnesium sulfate 4 grams, folic acid 1
gram, vitamin B12 1 mg, are administered for severely ill patients who
either present or return to the clinic with severe symptoms. In period 1
(April-September, 2020) 6/320 (1.9%) and 1/320 (0.3%) patients that
were hospitalized and died, respectively. In period 2,
(September-December, 2020) 14/549 (2.6%) and 1/549 (0.18%) were
hospitalized and died, respectively. For comparison, we used the
Cleveland Clinic COVID-19 hospitalization calculator and based on
average age and comorbidities the expected rate of hospitalization for
both periods was 18.5%. The cumulative mortality among confirmed and
suspected COVID-19 in Collin, Dallas, Denton, and Tarrant counties was
0.76, 1.04, 0.90, and 0.97. As a result, our early ambulatory treatment
regimen was associated with estimated 87.6% and 74.9% reductions in
hospitalization and death respectively, p<0.0001. Conclusions.
We conclude that early ambulatory, multidrug therapy is associated with
substantial reductions in hospitalization and death compared to
available rates in the community. Prompt ambulatory treatment should be
offered to high-risk patients with COVID-19 instead of watchful watching
and late-stage hospitalization for salvage therapies.
Development of Home Economics Education for Life Quality in Latvia
Authors:   Latvia University of Life Sciences and Technologies, Pridane Aija ,   Latvia University of Life Sciences and Technologies, Vronska Natalja ,   Latvia University of Life Sciences and Technologies, Lice-Zikmane Iveta ,   Latvia University of Life Sciences and Technologies
Published: January 2021

The research “Development of Home Economics Education for Life Quality in Latvia” is based on authors’ experience gained in long-term activities. The study is a scientific monograph, the materials is approbated in authors’ doctoral thesis and in scientific publications. The Home Economics education in Latvia has significantly changed from the acquisition of a simple, practical, narrow specification profession to the conscious, all-around development of a pupil’s individuality aimed at awareness of the quality of life and purposeful action to improve its quality. The aim of the book is to introduce the public to different aspects of the development of Home Economics and Technologies (Design and Technology) education for life quality in Latvia at schools and at University level. This book describes the research done by authors within Home Economics and Technologies sphere during 2000-2020 years in Latvia University of Life Sciences and Technologies (LLU), Institute of Education and Home Economics. Here are described the historical development of the Home Economics from 19th century until nowadays in Latvia, the change of paradigm of Home Economics studies, relationship between various aspects of the education in Home Economics and Technologies in the context of sustainable development, methodology structure for training teachers of Home Economics and Technologies at University level, understanding of life quality criteria of Home Economics and Technologies education in elementary school, research of pupils nutrition habits; the Information and Communication Technology Integration Skills Development Model in Home Economics and Technologies education for prospective teachers based on transformative digital learning, integration and student-centred approach implementation in the study process. The book is intended for researchers, University lecturers, teachers, master students, students, and other interested parties. The book is print with the financial support of the Association “School of Home Environment”.
Escritos do Visconde de Ouro Preto e outros Autores sobre o Golpe Republicano
Authors: Rangel Ronaldo Raemy , Raemy Rangel Gabriel Dolabela
Published: January 2021

Afonso Celso de Assis Figueiredo, Visconde de Ouro Preto, foi o ultimo Presidente do Gabinete Ministerial (ou Primeiro-ministro) do Império do Brasil. Após a Proclamação da República, no exílio, escreveu um folhetim intitulado Advento da ditadura militar no Brasil, no qual oferece sua versão sobre o que chamou de “sublevação militar que derrubou a monarquia brasileira”. Baseado no texto de Ouro Preto e em outros autores que relatam os eventos que deram origem a República, o artigo pretende sustentar que a verdadeira causa que esteia o do movimento republicano não é a republica em si, mas a descentralização do poder e o estabelecimento de um pacto federativo no país. O texto defende também, que os eventos que geraram o estabelecimento da república, em certo sentido, se deram de forma precipitada, sem comando e, principalmente, sem envolvimento popular, caracterizando-se como um golpe, sendo que o relato do Visconde de Ouro Preto, a despeito de contra-argumentos que lhe possam ser apresentados, é o fio condutor da argumentação que o artigo apresenta.