bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical Experiences in Collegiate Nursing Education
Authors: Ross Dennis G
Published: May 2007

Clinical Experiences in Collegiate Nursing Education. Joellen Watson Hawkins. Springer Publishing Company, 200 Park Ave S, New York, NY 10003, 1981, 116 pp, $11.50 paperback.
Coping with the Joint Commission: The New Quality Assurance, Third Generation
Authors: HENNESSY JULIETTE
Published: May 2007

Coping with the Joint Commission: The New Quality Assurance, Third Generation, second ed. By Jacqueline P. Gary 1987, 210 pp $29 paperback
Stress and the Manager
Authors: McConnell Edwina A
Published: May 2007

Stress and the Manager. Karl Albrecht. Prentice Hall, Inc, Englewood Cliffs, NJ 07632, 1979.
Surgical Infections
Authors: Glenn Georgia R
Published: May 2007

Lewis M Flint, Donald E Fry, Surgical Infections, 1982, Medical Examination Publishing Co. Inc, 969 Steward Ave, Garden City, NY 11530, 180, $24.50.
I'm Dying to Take Care of You … Nurses & Codependence: Breaking the Cycles
Authors: Collins Marjorie A.
Published: May 2007

I'm Dying to Take Care of You … Nurses & Codependence: Breaking the Cycles By Candace Snow, David Willard 1989, 186 pp $9.95 paperback
Readings in Nursing Trends and Issues
Authors: Bandell Kay J.
Published: May 2007

Readings in Nursing Trends and Issues Edited by Carol A. Lindeman, Marylou McAthie 1990, 533 pp $19.95 paperback
Tubal Reconstructive Surgery
Authors: Berger Pamela H.
Published: May 2007

Tubal Reconstructive Surgery By Ginter Sotrel 1990, 281 pp $75.00 clothbound
HIV Infection: Prevention and Care
Authors: DeStefano Alicia
Published: May 2007

HIV Infection: Prevention and Care 1990, 61 pp o charge
Ambulatory Care Quality Assurance Manual
Authors: Patterson Marla
Published: May 2007

Ambulatory Care Quality Assurance Manual By Howard S. Rowland, Beatrice L. Rowland 1990, 385 pp $115 loose‐leaf
Basic and Clinical Pharmacology
Authors: Bashline Dianna
Published: May 2007

Basic and Clinical Pharmacology, fourth ed. Edited by Bertram G. Katzung 1989, 897 pp $32 paperback
TEMPERATURE MEASUREMENT
Authors: Abbott Cynthia A.
Published: May 2007

Temperature and temperature measurement after induced hypothermia T. Heidenreich, M. Giuffre, J. Doorley Nursing Research Vol 41 (September/October 1992) 296–300
DUAL‐CAREER FAMILIES
Authors: Noss Vicki A.
Published: May 2007

Quality of life in dual‐career families: Commuting versus single‐residence couples B. Bunker et al Journal of Marriage and the Family Vol 54 (May 1992) 399–407
stress and coping strategies of nurse executive
Authors: WARD Suzanne F.
Published: May 2007

stress and coping strategies of nurse executive, C C Scalzi Journal of Nursing Administration Vol 18 (March 1988) 34–37
Comparisons of rectal, femoral, axillary, and skin‐to‐mattress temperatures in stable neonates
Authors: Takahashi Jacklyn J.
Published: May 2007

Comparisons of rectal, femoral, axillary, and skin‐to‐mattress temperatures in stable neonates, M T Kunnel, et al, Nursing Research Vol 37 (May/June 1988) 162–164
Video recording trauma resuscitations: An effective teaching technique
Authors: Strzelecki Lorna R.
Published: May 2007

Video recording trauma resuscitations: An effective teaching technique, D B Hoyt, et al, The Journal of Trauma Vol 28 (April 1988) 435–440
Practical Guide to the Care of the Surgical Patient
Authors: Sullins Mary Lou
Published: May 2007

Practical Guide to the Care of the Surgical Patient, third ed. By Robert L. McEntyre 1989, 348 pp $22.95 spiral bound
Mastering the Nursing Process: A Case Method Approach
Authors: Hennessy Juliette
Published: May 2007

Mastering the Nursing Process: A Case Method Approach By Jean D'Meza Leuner, Anne Keiran Manton, Dorothy Bagnell Kelliher, Sharon P. Sullivan, Meg Doherty 1990, 494 pp $24.95 paperback
Safety Guide for Health Care Institutions
Authors: Phillips Susan S.
Published: May 2007

Safety Guide for Health Care Institutions, fourth ed. By Linda F. Chaff 1989, 209 pp $35 AHA members, $45 nonmembers paperback
Pocket Guide to Nursing Diagnoses
Authors: Cozad Janet
Published: May 2007

Pocket Guide to Nursing Diagnoses, third ed. By Mi Ja Kim, Gertrude K. McFarland, Audrey M. McLane 1989, 333 pp $15.95 paperback
Nursing Theories: The Base for Professional Nursing Practice
Authors: Miehl Jann L.
Published: May 2007

Nursing Theories: The Base for Professional Nursing Practice, third ed. Edited by Julia B. George 1990, 401 pp $26.95 paperback
Operating Room Nursing: Perioperative Practice
Authors: Snyder Rhonda P.
Published: May 2007

Operating Room Nursing: Perioperative Practice, second ed. By Linda K. Groah 1990, 405 pp $ 39.95 hardcover
SPECIALIZATION
Authors: BARONI‐KAESTNER MARY ANN
Published: May 2007

The ICU Book By Paul L. Marino 1991, 713 pp $39.50 paperback
VERBAL ABUSE
Authors: DIOMEDE BARBARA
Published: May 2007

Verbal abuse nationwide, part II: Impact and modifications K cox Nursing Management Vol 22 (March 1991) 66–69
ORIENTATION PROGRAMS
Authors: JOHNSON JANE H.
Published: May 2007

Self‐directed learning and nursing orientation programs: Are they compatible? J L Prociuk The Journal of Continuing Education in Nursing Vol 21 (November/December 1990) 252–256
Statistical Priniciples in Health Care Information
Authors: Minckley Barbara B
Published: May 2007

S Kilpatrick Jr., Statistical Priniciples in Health Care Information, 1973, University Park Press, Baltimore, 228, pp.
Modern Medicine for Nurses
Authors: Reed Elizabeth A
Published: May 2007

J Gibson, Modern Medicine for Nurses, 2nd ed., 1972, Blackwell Scientific Publications, Oxford, 343, pp.
Changes in AORN Bylaws proposed
Authors: Huff Sarah Davis
Published: May 2007

These changes in the AORN Bylaws will be considered by the House of Delegates at the 1981 AORN Congress, March 8 to 13, in Dallas. The proposals would change delegate representation for members‐at‐large and establish an Editorial Board for the AORN Journal. Both the current and proposed bylaws are printed below. Accompanying statements follow each proposal.

These proposals are published for review by the membership. Please examine them carefully so you can instruct your delegates how to vote at Congress.
Anesthesiology: Problem‐oriented Patient Management
Authors: Davis Janice L
Published: May 2007

Anesthesiology: Problem‐oriented Patient Management. Fun‐Sun F Yao, Joseph F Artusio Jr, eds. J B Lippincott Co, East Washington Square, Philadelphia, PA 19105, 1983, 466 pgs, $32.50.
Nursing Issues and Nursing Strategies for the Eighties
Authors: Philbrick Mark
Published: May 2007

Nursing Issues and Nursing Strategies for the Eighties. Bonnie Bullough, Vern Bullough, Mary Claire Soukup, eds. Springer Publishing Company, Inc, 220 Park Ave S, New York, NY 10003, 1983, 338 pp, $17.95 paperback.
Documenting Care: Communication, the Nursing Process and Documentation Standards
Authors: Richardson Karen
Published: May 2007

Frances T. Fischbach, Nursing Process, Documenting Care: Communication, the Nursing Process and Documentation Standards, 1991, 677, $24.95 paperback
Ethics in Health Service Management
Authors: Hodges Sharon R.H.
Published: May 2007

Kurt Darr, et al., Ethics, Infection control, 1991, 292, $38 hardcover
Drawing the Line: Life, Death, and Ethical Choices in an American Hospital
Authors: Sapnas Kathryn G.
Published: May 2007

Samuel Gorovitz, et al., Ethics, Drawing the Line: Life, Death, and Ethical Choices in an American Hospital, 1991, 195, $19.95 hardcover
Crisis Intervention–Theory and Methodology
Authors: McConnell Edwina A
Published: May 2007

Donna C Aguilera, Janice M Messick, C V Mosby Co, 4th ed., 1982, F A Davis Co, 11830 Westline Industrial Dr, St Louis, Mo 63141, 194, $12.95.
Relationships among perceived supervisor communication, nurse morale, and sociocultural variables
Authors: Markey Bernadine T. ,   Nursing Research Committee
Published: May 2007

Relationships among perceived supervisor communication, nurse morale, and sociocultural variables C W Kennedy, C T Camden, G M Timmerman Nursing Administration Quarterly Vol 14 (Summer 1990) 38–46
First‐line Patient Care Management
Authors: Shaneberger Kathy E
Published: May 2007

Barbara J Stevens, First‐line Patient Care Management, 2nd ed., 1983, Aspen Systems Corp, 1600 Research Blvd, Rockville, Md 20850, 195, $22.50.
Professionalism and the Empowerment of Nursing
Authors: Owen Charlotte
Published: May 2007

Professionalism and the Empowerment of Nursing, 1982, American Nurses' Association, 2420 Pershing Rd, Kansas City, Mo 64108, 76
The Socialization of Neophyte Nurses
Authors: Placek Marjorie Y
Published: May 2007

Loretta C Myers, The Socialization of Neophyte Nurses, 1982, UMI Research Press, University Microfilms International, Ann Arbor, Mich 48106, 144, 39.95.
PERCUTANEOUS INJURIES AMONG OPERATING ROOM PERSONNEL
Authors: Watson Donna S. ,   Nursing Research Committee
Published: May 2007

J. Jagger, et al., PERCUTANEOUS INJURIES AMONG OPERATING ROOM PERSONNEL, Presentation at the Conference on Preventing Bloodborne Pathogen Transmission in Surgery and Obsterics Atlanta, Feb 14, 1994
Nursing Research: Principles and Methods
Authors: Marrone Stephen R.
Published: May 2007

Nursing Research: Principles and Methods, third ed. Denise F. Polit, Bernadette P. Hungler. J B Lippincott Co, E Washington Square, Philadelphia, PA 19105, 1987, 571 pp, $27.50 clothbound.
The Changing Image of the Nurse.
Authors: Edwards Mary Jane C.
Published: May 2007

The Changing Image of the Nurse. Philip A. Kalisch, Beatrice J. Kalisch. Addison‐Wesley Publishing Co, Health Sciences Div, 2725 Sand Hill Rd, Menlo Park, CA 94025, 1987, 259 pp, $17.95 paperback.
Principles of Surgical Technique: The Art of Surgery
Authors: Matthews Kay
Published: May 2007

Principles of Surgical Technique: The Art of Surgery Surgery,By Gary G. Wind, Norman M. Rich 1987, 280 pp $34.50 paperback
Current Surgical Diagnosis and Treatment
Authors: Edwards Mary Jane C.
Published: May 2007

Current Surgical Diagnosis and Treatment, eighth ed. Edited by Lawrence W. Way 1988, 1233 pp $34.50 paperback
Understanding ethical issues, psychiatric needs of patient care: Effective Approaches to Patients' Behavior
Authors: Ross Dennis
Published: May 2007

Gladys B. Lipkin, Roberta G. Cohen, Effective Approaches to Patients' Behavior, third ed., 1986, Springer Publishing Co,, 175 5th Ave, New York, NY 10010, 282, $16.95 paperback.
Handbook of Emergency Nursing: The Nursing Process Approach
Authors: Persson June C.
Published: May 2007

Handbook of Emergency Nursing: The Nursing Process Approach By Linda Mowad, Diane C. Ruhle 1988, 391 pp $36.50 paperback
Commonsense Approach to Coronary Care: A Program
Authors: Marrone Stephen R.
Published: May 2007

Commonsense Approach to Coronary Care: A Program, fifth ed. By Marielle Ortiz Vinsant, Martha I. Spence 1988, 681 pp $27.95 spiral bound
Comprehensive Perioperative Nursing Review
Authors: GAEHLE KAY E.
Published: May 2007

Comprehensive Perioperative Nursing Review By Susan S. Fairchild 1993, 356 pp $34.95 paperback
PDR Guide to Drug Interactions, Side Effects, Indications
Authors: McEwen Donna R.
Published: May 2007

PDR Guide to Drug Interactions, Side Effects, Indications, 47th ed Edited by Mukesh Mehta 1993, 1,300 pp $45.95 hardcover
Propensity for Obtaining Alcohol Through Shoulder Tapping
Authors: Toomey Traci L. , Fabian Lindsey E. A. , Erickson Darin J. , Lenk Kathleen M.
Published: May 2007

Background: Underage youth often obtain alcohol from adults who illegally provide the alcohol. One method for obtaining alcohol from adults is shoulder tapping, where youth approach an adult outside an alcohol establishment and ask the adult to purchase alcohol for them. The goal of this study was to assess what percentage of the general and youth‐targeted adult population approached outside of a convenience/liquor store will agree to purchase and then provide alcohol to individuals who appear under age 21.

Methods: We conducted 2 waves of pseudo‐underage shoulder tap request attempts, using requesters who were age 21 or older but appeared 18 to 20 years old. In both waves, requests were conducted at randomly selected liquor and convenience stores, requesters explained that the reason they were asking the adult was because they did not have their identification with them, and requesters asked the adults to purchase a 6‐pack of beer. During wave 1, we conducted 102 attempts, with the requester approaching the first adult entering the store alone. During wave 2, we conducted 102 attempts where the requester approached the first casually dressed male entering the store alone who appeared to be 21 to 30 years old.

Results: During wave 1, 8% of the general sample of approached adults provided alcohol to the pseudo‐underage requesters. The odds of adults providing alcohol in urban areas were 9.4 times greater than in suburban areas. During wave 2, 19% of the approached young men provided alcohol to the requesters. No requester, request attempt, establishment, or community characteristics were associated with request attempt outcomes during wave 2.

Conclusions: A small percentage of the general population of adults will agree to provide alcohol to underage youth when approached outside an alcohol establishment. The likelihood of underage youth obtaining alcohol through shoulder tapping increases substantially if the youth approach young men.
All Three Trimester Binge Alcohol Exposure Causes Fetal Cerebellar Purkinje Cell Loss in the Presence of Maternal Hypercapnea, Acidemia, and Normoxemia: Ovine Model
Authors: Ramadoss Jayanth , Lunde Emilie R. , Piña Kevin B. , Chen Wei‐Jung A. , Cudd Timothy A.
Published: May 2007

Background: The third trimester equivalent has been identified, both in rat and sheep models, as a period of cerebellar vulnerability to alcohol‐mediated injury. We wished to determine whether alcohol exposure throughout gestation results in greater injury compared with exposure limited to the third trimester equivalent. While this question has previously been addressed in the rat model, where the third trimester equivalent occurs postnatally, it has not yet been addressed in an animal model where all 3 trimester equivalents occur prenatally, as in the ovine. We also wished to correlate cerebellar Purkinje cell loss to alcohol‐mediated alterations in maternal arterial pH and blood gases as these responses might be important mechanistically in mediating the damage.

Methods: Three groups of pregnant sheep were used: an untreated normal control group, a saline control group, and an alcohol group (1.75 g/kg of the body weight). The alcohol exposure regimen was designed to mimic a human binge pattern; alcohol was administered intravenously on 3 consecutive days, followed by 4 days without alcohol, beginning day 4 of gestation, continuing to the end of the third trimester equivalent of human brain growth, day 132 of gestation.

Results: All 3 trimester alcohol‐exposed fetal brains exhibited significant deficits in cerebellar volume and Purkinje cell number compared with those of control subjects. We did not detect a difference in the reduction of Purkinje cell number when comparing between all 3 trimester and third trimester alcohol exposure studies. The neuronal loss was accompanied by maternal hypercapnea, acidemia, and normoxemia.

Conclusions: These findings demonstrate in an ovine model where all 3 trimester equivalent of brain growth occur in utero that the fetal cerebellar Purkinje cells are more sensitive to the timing of alcohol exposure and less so to the duration of exposure. Decreases in maternal PaO2 were not detected, suggesting that maternal hypoxia does not play a role in fetal Purkinje cell loss. And finally, we conclude that alcohol‐induced changes in maternal arterial pH may play a role in alcohol‐mediated developmental brain injury.
Nematicidal activity of onion (Allium cepa) oil and its components against the pine wood nematode (Bursaphelenchus xylophilus)
Authors: Choi In-Ho , Shin Sang-Chul , Park Il-Kwon
Published: May 2007

Onion oil and its components were tested for their nematicidal activity
against the pine wood nematode, Bursaphelenchus xylophilus, with 96-well
plate bioassays. Responses varied with test materials and concentration.
Good nematicidal activity against male, female and juvenile nematodes of B.
xylophilus was achieved with onion oil. The LC50 values of onion oil against
male, female and juvenile pine wood nematodes were 17.6, 13.8 and 12.1 μg
ml−1, respectively. Analysis by gas chromatography-mass spectrometry led to
the identification of four major sulphur compounds: propyl disulphide,
propyl trisulphide, methyl propyl disulphide and methyl propyl trisulphide.
These four compounds and propyl sulphide and methyl propyl sulphide were
tested individually for their nematicidal activities against pine wood
nematode. LC50 values of propyl trisulphide and methyl propyl trisulphide
against juvenile nematode were 5.0 and 22.9 μg ml−1, respectively. Other
sulphur compounds showed weak activity.
Morphological and molecular characterisation of a new awl nematode, Dolichodorus mediterraneus sp. n. (Nematoda: Dolichodoridae), from Spain
Authors: Guirado Domingo Jiménez , Murillo Navarro Raquel M. , Liébanas Gracia , Landa Blanca B. , Castillo Pablo
Published: May 2007

A new species of awl nematode, Dolichodorus mediterraneus sp. n., is
described from southern Spain. The new species is described and illustrated
by light microscopy and scanning electron microscopy studies from specimens
collected in a sandy soil around roots of cork oak (Quercus suber L.) from
Hato Raton, Aznalcázar (Seville), southern Spain. Dolichodorus mediterraneus
sp. n. is characterised by a prominent, rounded, lip region, which is offset
from the body and has four to six very fine annuli; lateral fields areolated
with three lines, ending posterior to anus level; tail 72-122 μm long,
abruptly tapering to an acuminate, often spicate, terminus; tail projection
51-79 μ m long; spicules ventrally arcuate, 33-42 μm long; gubernaculum
slightly ventrally curved, 14-22 μm long. Scanning electron microscopy
observations showed a similar en face pattern to other Dolichodorus spp.
Molecular data from the ribosomal large subunit D2-D3 expansion segment of
28S rDNA from paratypes yielded a single fragment of approximately 800 bp.
This is the first record of the genus Dolichodorus in Spain and only the
second in Europe. A key to species is provided.
Life cycle and calculation of the intrinsic rate of natural increase of two bacterivorous nematodes, Panagrolaimus sp. and Poikilolaimus sp. from chemoautotrophic Movile Cave, Romania
Authors: Muschiol Daniel , Traunspurger Walter
Published: May 2007

The life cycle and somatic growth of two bacterivorous nematodes, Panagrolaimus sp. and Poikilolaimus sp., isolated from chemoautotrophic microbial mats in Movile Cave, Romania, were studied in monoxenic cultures at 20°C with Escherichia coli as the food source. A method is described that allows simultaneous investigation of the somatic growth pattern, age-specific fecundity, and age-specific mortality of single individuals with high accuracy. Somatic growth curves of the species are presented. During juvenile development, both species showed a strict linear increase in body length, whereas body weight increased exponentially. Growth was continuous without lag phases. The relationships between fresh weight, W (μg), and body length, L (mm), were W = 1.6439L2.7672 for Poikilolaimus sp. and W = 0.2085L4.0915 for Panagrolaimus sp. Life tables and fecundity schedules for the two species are presented. In addition, demographic parameters were calculated. For Panagrolaimus, the intrinsic rate of natural increase (rm), calculated according to the Lotka equation, was 0.309, the net reproductive rate (R0) 64, the mean generation time (T) 13.8 days and the minimum generation time (Tmin) 9.5 days. The corresponding values for Poikilolaimus were rm = 0.165, R0 = 108, T = 26.2 and Tmin = 19.5. Panagrolaimus produced fewer progeny than Poikilolaimus during its life but exhibited faster population growth due to its faster maturation. It showed a distinct post-reproductive period, whereas Poikilolaimus remained fertile until death.
The effects of different anaesthetic agents on the estimation of uterine vascular permeability in mice
Authors: Milligan S. R. , Edwards C.
Published: May 2007

Vascular permeability in the uterus and other tissues of mice was assessed using the accumulation of 125I-human serum albumin 30 min after its intravenous injection. The anaesthetic agent employed for the 125I-albumin injection differentially affected the estimates of vascular permeability: intraperitoneal (i.p.) tribromoethanol of pentobarbitone sodium produced significantly higher values for the uterus and body wall than ether. The i.p. administration of either Saffan or pentobarbitone sodium reduced estimates of vascular permeability in the duodenum. These results emphasize the importance of the choosing a suitable anaesthetic agent in vascular studies of the uterus and other abdominal tissues.
Gross anatomy of the liver, biliary tree, and pancreas in the black-tailed prairie dog (Cynomys ludovicianus)
Authors: Grace P. A. , McShane J. , Pitt H. A.
Published: May 2007

The gross anatomy of the liver, extrapetatic biliary tree, sphincter of Oddi, and pancreas in the black-tailed prairie dog ( Cynomys ludovicianus), a widely used animal model for investigations into biliary physiology, pathophysiology, and pathology, was studied in 10 animals. The liver consists of 4 lobes, the left lateral, median, right lateral, and caudate. The gallbladder ties on the ventral surface of the right lobule of the median lobe. The cystic and hepatic ducts unite to form the common bile duct which enters the duodenum approximately 5 mm distal to the pylorus. The lower end of the common duct dilates forming an ampulla which is surrounded proximally by a band of circular muscle fibres which constitute the choledochal sphincter. The pancreatic duct opens separately into the duodenum approximately 80 mm from the pylorus. Earlier physiologic studies have demonstrated that the choledochael sphincter has intrinsic motility distinct from the duodenum.
Assessment of discomfort in rats with hepatomegaly
Authors: Beynen A. C. , Baumans V. , Bertens A. P. M. G. , Haas J. W. M. , Van Hellemond K. K. , Van Herck H. , Peters M. A. W. , Stafleu F. R. , Van Tintelen G.
Published: May 2007

An attempt was made to assess discomfort in rats with hepatomegaly induced by feeding a high cholesterol, high cholate diet. After 8 weeks, the rats displayed a more than two-fold increase in liver weight when compared with controls fed a commercial diet. In a small open field test, behaviour of rats with hepatomegaly was similar to the controls. Of 9 parameters scored per rat, only the response to pressure on the right hypo-chondrium (tension of overlying muscles) scored higher than in control animals. There was considerable between-assessor variation in the assignment of scores. It is suggested, tentatively, that hepatomegaly in rats caused by cholesterol plus cholate feeding, may not cause extreme discomfort. Upon 'blind' palpation of control and test rats, an average of 60% of the rats with hepatomegaly were classified correctly.
The effectiveness of Ivomec and Neguvon in the control of murine mites
Authors: Baumans V. , Havenaar R. , Van Herck H. , Rooymans T. P.
Published: May 2007

The effectiveness of different methods of external applications of Neguvon and Ivomec for treating infestations with Myobia musculi and Myocoptes spp. in conventional colonies of laboratory mice was investigated.

Ivomec appeared to be effective over a longer period of time than Neguvon. There was no difference in the results obtained with different methods of application, but spraying seems to be more practical for large colonies of mice than individual dipping.
Blood coagulation studies in guineapigs (Cavia porcellus)
Authors: Kaspareit J. , Messow C. , Edel J.
Published: May 2007

Blood coagulation studies were performed on 45 healthy, adult guineapigs. Additionally thrombelastograms of 30 animals were recorded. Guineapigs revealed short partial thromboplastin times and euglobulin lysis times, but long prothrombin times and thrombin times. Fibrinogen values were within the range of human normal values. Biphasic ADP-induced aggregation of platelets, as occurs in man, was found in 29% of the animals. Short r (reaction time until the beginning of clot formation) and k times (time from the beginning of clot formation until an amplitude of 20 mm) of their thrombelastograms indicate, that whole blood clotting is enhanced in guineapigs. Higher maximum amplitudes in this species suggest a stronger clot stability than in man.
Mebendazole for worming mice: effectiveness and side effects
Authors: Baskerville M. , Wood M. , Newton C. M.
Published: May 2007

The use of mebendazole-treated diet (60 ppm) effectively controlled Hymenolepis nana and Aspiculuris tetraptera in a large mouse breeding colony. In a 3 generation pilot study using a medicated diet, there was some reduction in litter size and in female growth rate and an overall 2·07% incidence of kinky tails in the offspring. When the whole mouse colony was fed mebendazole-treated diet, a high incidence of kinky tails (maximum 46% of weaned offspring) occurred.
Rearing cynomolgus monkeys (Macaca jascicularis) on surrogate mothers with bottle feeding
Authors: Timmermans P. J. A. , Röder E. L. , Kemps A. M. L. J.
Published: May 2007

Fifty-two cynomolgus monkeys were reared in peer groups on surrogate mothers and fed by bottle during the first months of life. A description of the technique of bottle feeding and the structure of surrogate mothers is presented. Results are shown in a growth curve. Inter-individual differences in body weight were very large. The mean weight was higher in males than in females, but no significant sex differences in growth occurred. The weight of mother-reared infants stayed within the standard deviation of the mean weight of the artificially-reared subjects.
Aprotinin reduces hypothermic mortality-an experimental model
Authors: Bhargava N. , Dhasmana K. M. , Banerjee A. K. , Faithfull N. S. , Fennema M. , Vermij M. , Erdmann W.
Published: May 2007

In order to test the postulate that posthypothermic damage may be caused by protease activation, the effect of the administration of aprotinin on hypothermic mortality was investigated in anaesthetized rabbits. A group of 6 animals received 40.000 KIU aprotinin intravenously prior to the induction of hypothermia by surface cooling and this was followed by a further 35.000 KIU each hour for 5 h. The animals were cooled to 29°C and then rewarmed. A control group received equal volumes of physiological saline. The aprotinin treated animals survived, whereas all the control group died within 7 days, 5 of them within 24 h. The haemodynamic, biochemical and haematological changes in the two groups are reported.
Infantile disease with microvesicular fatty infiltration of viscera spontaneously occurring in the C3H-H-2° strain of mouse with similarities to Reye's syndrome
Authors: Koizumi T. , Nikaidoi H. , Hayakawa J. , Nonomura A. , Yoneda T.
Published: May 2007

The clinical, biochemical and histopathological findings of an infantile disease occurring in the C3H-H-2° strain of mice, which has similarities with Reye's syndrome in children, is described.
A simple method for prevention of coprophagy in the mouse
Authors: Ebino K. Y. , Yoshinaga K. , Saito T. R. , Takahashi K. W.
Published: May 2007

A series of studies of coprophagy in mice has been conducted from the viewpoints of behaviour and nutrition. Since it was necessary to prevent coprophagy to investigate its significance, an attempt was made to devise a re-strainer. A polyethylene bottle was cut and fixed to the mouse so as to prevent its head from reaching its anus when faeces were excreted. The animals were also housed in cages with floors of larger mesh size in order to let the faeces fall through.
Embryonic death in pregnant rats owing to intercurrent infection with Sendai virus and Pasteurella pneumotropica
Authors: Carthew P. , Aldred P.
Published: May 2007

During an outbreak of Sendai virus infection in a colony of rats used for embryo production, severe lung lesions due to secondary colonization of the rat lungs with Pasteurella pneumotropica were noted. The effect on pregnancy was to cause embryonic death and resorption, leaving a deciduoma with trophoblastic giant cells as the only embryonic remnants. Up to 30% of fetuses in each pregnant animal were affected at the time of severe maternal lung lesions. Heavy growths of Pasteurella pneulnotropica were obtained from the lungs of all affected dams.

The formation of deciduomas as a result of embryonic death was due to the indirect effect of damage to the lungs during pregnancy rather than the direct pathogenic effect on the developing embryo of the microbial organisms isolated.
The behaviour of chickens, mice and rats during euthanasia with chloroform, carbon dioxide and ether
Authors: Blackshaw J. K. , Fenwick D. C. , Beattie A. W. , Allan D. J.
Published: May 2007

Euthanasia of chickens, young and mature rats, and mice was assessed using chloroform, carbon dioxide and ether. Behavioural patterns were recorded to give some indication of the stress involved. Carbon dioxide induced collapse faster (11·2 ± 0·4 s) than chloroform(18·9 ± 0·4 s) or ether (> 60 s). With regard to the time taken to death, in carbon dioxide mice had the shortest time (48 ± 10 s) and mature rats had the longest time (135 ± 10 s). In chloroform, the only difference was the delayed onset of death (127 ± 10 s) in the chicken. Behavioural patterns were similar for the chicken in carbon dioxide and chloroform, except for wing flapping, even when unconscious, in carbon dioxide. Chloroform is recommended as more aesthetically acceptable for euthanasia of chickens. Carbon dioxide is recommended for the euthanasia of both rats and mice, considering behavioural criteria. Ether is unsuitable as a euthanasia method as it is dangerous, slow acting and an irritant.
A simple method for measurement of the haemoglobin binding capacity of canine haptoglobin
Authors: Batchelor J. , Fuller J. , Woodman D. D.
Published: May 2007

The potential of a series of related compounds to induce haemolytic anaemia in dogs highlighted the need for a reliable and sensitive technique to identify changes in plasma haptoglobin concentration. An indirect method established for human samples was adapted for use with canine plasma. This method measures the haemoglobin binding capacity of plasma, which is directly proportional to the functional haptoglobin concentration. The efficacy of this technique was investigated on samples taken from Beagle dogs which had previously received small quantities of water intravenously. A substantial reduction in haemoglobin binding capacity was recorded before other haematological parameters were significantly affected. It was concluded that measurement of haemoglobin binding capacity by this method provides a valid reflection of haptoglobin status in the dog.
Prolapsus vaginae in the IIIVO/JU rabbit
Authors: Van Herck H. , Hesp A. P. M. , Versluis A. , Zwart P. , Van Zutphen L. F. M.
Published: May 2007

In a specified pathogen free (SPF) breeding colony of IIIVO/JU rabbits 8 cases of prolapsus vaginae occurred in 5 years. Clinically the animals were in shock. Haematocrits ranged from 9 to 15%. The prolapses started from the submucosal layer of the proximal part of the vestibulum vaginae. The prolapsed tissue consisted of over-expanded blood-sinuses. Between the sinuses signs of an inflammatory reaction were present.

All 8 animals were in a period of increasing sexual activity when the prolapse developed. The 8 rabbits were closely related, indicating a possible hereditary defect.
Pygomelia in a C3H/Crl mouse: case report
Authors: Rao S. Harinarayana
Published: May 2007

Accessory hind limbs (pygomelia) were found in a male pup born in our colony of C3H/Crl mice. This malformation has not previously been reported in mice.
The effects of intracage ventilation on micro environmental conditions in filter-top cages
Authors: Lipman Neil S. , Corning Brian F. , Coiro Michael A.
Published: May 2007

Filter-top cages, while effective in reducing cross contamination by particulate material including microbes, can also cause accumulation of the waste gases carbon dioxide and ammonia as well as increased intracage relative humidity. A prototype system which provided each cage with 23 air changes per hour through a nozzle inserted in the filter lid was evaluated. The ventilated cageing system was effective in reducing intracage carbon dioxide, ammonia and relative humidity levels. Mean weekly carbon dioxide levels were 2900 ppm lower, ammonia levels 240 ppm lower and intracage relative humidity levels 8% lower in the ventilated cages than in unventilated controls.
Echocardiographic parameters and indices in the normal Beagle dog
Authors: Crippa L. , Ferro E. , Melloni E. , Brambilla P. , Cavalletti E.
Published: May 2007

M-mode and two-dimensional echocardiographic measurements were made from the right sternal border of 50 healthy Beagles (25 males and 25 females) approximately 7 months old. The dogs were conscious and standing during the investigation.

The following parameters, in systole and diastole, were measured on the echocardiographic images: left ventricular posterior wall thickness (LVWT); intraventricular septum thickness (IST); left ventricular internal dimension (LVID); and circumference (LVC). Fractional shortening (FS) and ejection fraction (EF) were also calculated.

Mean, standard deviation, range and coefficient of variation are reported for each echocardiographic parameter and for body weight. Males and females were considered separately and together. Each parameter was analysed statistically to check for differences between the sexes and for correlations with body weight. A statistically significant difference between the sexes was only observed for LVWT in systole and diastole. A linear regression with body weight was obtained only for LVID in systole and in diastole. The results show that morphofunctional cardiac homogeneity is independent of size in dogs of this breed and age.
Developmental and regressive changes in the testes of the Himalayan rabbit
Authors: Tsunenari Ichiro , Kast Alexander
Published: May 2007

The testes of 81 Himalayan rabbits, controls in toxicity studies, and 113 purpose-bred rabbits of various age groups from birth to 2 years were studied. In mature male rabbits, regressive changes in the seminiferous tubules including the multinucleated spermatid giant cells were common and showed a tendency for age-related and seasonal differences. The finding is considered as a remnant of the previous seasonal and possibly also social testicular regression in wild living animals. The giant cells develop from the syncytium of the germinative epithelium and have parallels in phylogenesis.
Rabbit encephalitozoonosis in Kenya
Authors: Wesonga H. O. , Munda M.
Published: May 2007

Encephalitozoon cuniculi infection was diagnosed in a laboratory rabbit breeding colony at Muguga, Kenya. This is the first report of the disease in rabbits in Kenya. Post-mortem examination showed gross renal lesions and the presence of the parasite in histological sections of the cerebrum and cerebellum. On Gram stain, spores were observed in the kidney sections.
Haematological and serum biochemical values in hairless and haired descendants of Mexican hairless dogs
Authors: Kimura T. , Ohshima S. , Doi K.
Published: May 2007

Haematological and serum biochemical measurements were carried out in 1-year-old hairless and haired hybrids derived from the Mexican hairless dog (MHD). These hybrids included F1 hybrids obtained from male MHD and female Beagles, and BCF1 hybrids obtained from male hairless F1 and female Beagles. There were no significant differences between F1 and BCF1 hybrids, nor between male and female hybrids. Except for red blood cell counts, haemoglobin concentrations and packed cell volumes which were slightly higher in MHD-descendants than in Beagles, there were no differences for haematological and serum biochemical findings between hairless and haired hybrids when compared to age-matched Beagles.
A modified anaesthetic induction chamber for rats
Authors: Gwynne B. J. , Wallace J.
Published: May 2007

The anaesthetic induction chamber for rats described in this paper has been designed for use in conjunction with a controlled delivery of halothane/O2 mixture and an anaesthetic scavenger system. Using this system rapid induction of anaesthesia is achieved using low levels of anaesthetic vapour without risk to the operator.
Spinal dysplasia with stump tail and hind limb paralysis in a laboratory bred cat
Authors: Lansdown A. B. G. , Pate P.
Published: May 2007

A case is presented of a specified pathogen free bred cat which was apparently tail-less at birth and at three weeks of age revealed hind limb paralysis. The animal was euthanized at 4 weeks and X-radiography revealed an abnormal spinal curvature, greatly reduced caudal vertebrae and abnormal pelvic development. A small tail was dissected at post-mortem, but other abnormalities were not seen.
Euonymus europaeus lectin as an endothelial and epithelial marker in canine tissues
Authors: Roussell F. , Dalion J. , Wissocq J. C.
Published: May 2007

The Euonymus europaeus agglutinin (EEA) is an endothelial marker in mammalia. In canine tissues, 4 types of endothelial cells (general, nervous, arterial, hepatic) were identified by the presence of the EEA receptor and by its sensitivity to neuraminidase enhancement. In adult dogs, EEA binding saccharides had endothelial or epithelial distributions and reactivities similar to those described for human tissues. Different EEA reactivities were observed between fetal, neonatal and adult canine tissues mainly at the arterial level. These findings suggest that the development of the binding sites is not identical in dog and man. Related lectins and monoclonal antibodies were used to characterize the EEA binding site, and the probable structure of the EEA binding saccharide in endothelial cells appeared to be αGal (1,3) βGal (1,4) GIcNAc.
A method for hyperthermic treatment of mouse skin
Authors: Gragtmans N. J. , Jevcak J. J. , Mitchel R. E. J. , Morrison D. P. , McCann R. A. , Murphy J. W.
Published: May 2007

The Sencar mouse skin system is a recognized model for tumour initiation, promotion and progression. The current interest in the effect of hyperthermia on this multi-stage tumorigenesis model prompted the need for a technique to accurately heat a section of dorsal skin of a large number of mice for 30 min per heat treatment. In the technique described, experimental groups of 25 female Sencar mice were treated at 7-8 weeks of age under general methoxyflurane anaesthesia. Treatment consisted of the application of initiating and/or promoting agents with or without hyperthermia. For hyperthermic skin treatments, each group of mice was placed onto a platform in a water bath so that the dorsal skin of the mice was in contact with 44°C temperature controlled water.
Monitoring of blood gas parameters and acid-base balance of pregnant and non-pregnant rabbits (Oryctolagus cuniculus) in routine experimental conditions
Authors: Barzago M. M. , Bortolotti A. , Omarini D. , Aramayona J. J. , Bonati M.
Published: May 2007

Blood gas parameters and acid-base balance values were determined in adult pregnant New Zealand rabbits ( Oryctolagus cuniculus) in standard laboratory housing conditions and during anaesthesia with an association of ketamine-chlorpromazine, administered before surgical procedures. All the variables were also studied in adult non-pregnant female, used as controls. No differences in pH, sO2c, O2Hb, COHb, sO2m and a-vDO2 were found between pregnant and non-pregnant rabbits in physiological conditions and during anaesthesia. Ketamine-chlorpromazine and pregnancy seemed to change the other parameters used to assess the acid-base balance and the oxygenation conditions. Anaesthesia affected only Hb, O2Ct, O2Cap, CcO2 and P50. The additive effect of pregnancy and anaesthesia modified pCO2, pO2, HCO3-, TCO2, BEb, SBC, BEecf, A-aDO2, RI, MetHb, RHb, CaO2 and CvO2. The patterns described are close to those of other species, suggesting the New Zealand rabbit might be a reliable animal model for monitoring selected variables.
Unusual patterns of susceptibility to degradation of DNA isolated from tissues in Peromyscus californicus
Authors: Kass David H. , Hoffman Susan M. G.
Published: May 2007

Isolation of intact, high molecular weight genomic DNA from the livers of 2 subspecies of Peromyscus californicus without excessive degradation was typically unattainable, whereas highly intact DNA from livers of other Peramyscus (field mice) species is invariably obtained using the same isolation methods. Additionally, highly intact DNA was obtained from splenic tissues of adult P. californicus and hepatic tissue of juvenile animals, indicating that the phenomenon is tissue-specific and age-related.
Isolation of Acinetobacter calcoaceticus from the gastrointestinal tracts of SCID mice
Authors: Ohsugi Takeo , Shimoda Kouji , Maejima Kazuyoshi , Kagiyama Naoko , Takagi Hiroshi , Nomura Taisei
Published: May 2007

Acinetobacter calcoaceticus colonization was observed in the gastrointestinal tracts of C.B17- scid/seid (SCID) mice, while it was not observed in C.B17- scid/+ and C.B17-+/+ mice with normal immunity housed under the same conditions. A. calcoaceticus and other viable enteric bacteria were not isolated from any organs other than gastrointestinal tract in SCID mice. The mice colonized with this organism were apparently healthy and no significant visceral lesion was observed.
The influence of buprenorphine or bupivacaine on the post-operative effects of laparotomy and bile-duct ligation in rats
Authors: Liles Jane H. , Flecknell P. A.
Published: May 2007

The post-operative effects of laparotomy and common bile-duct ligation were investigated in rats. Bile-duct ligation caused a significant reduction in food and water consumption, body weight and locomotor activity in the immediate post-operative period. Animals which underwent laparotomy in which bile-duct ligation was not carried out (sham operated groups) had significantly less depression of food and water consumption and body weight than groups which underwent bile-duct ligation. The detrimental effects on food and water consumption and body weight could be significantly reduced by the administration of buprenorphine (0·05 mg/kg, s/c), but not by infiltration of the surgical wound with the long-acting local anaesthetic agent, bupivacaine. The reduction of the depressant effects of surgery on food and water consumption by the opioid analgesic buprenorphine suggests that some of these changes may be related to the presence of post-operative pain.
Haematological and plasma biochemical values for healthy Yucatan micropigs
Authors: Rispat G. , Slaoui M. , Weber D. , Salemink P. , Berthoux C. , Shrivastava R.
Published: May 2007

Blood samples ( n = 135) were collected from 36 male and 35 female 20±4-week-old Yucatan micro pigs and were analysed for 19 haematological and 18 plasma biochemical parameters at weeks 20, 24, 33, 46, 59, 71 and 80. For each parameter, the total number of analyses per sex, mean values, standard deviation, lowest and highest values, and 95% confidence intervals are presented as reference values for this breed. Age- and sex-related differences in these parameters are also discussed.
Light intensity and the oestrous cycle in albino and normally pigmented mice
Authors: Donnelly Harry , Saibaba Palle
Published: May 2007

The effects of light intensity (15-20 lux & 220-290 lux) on the oestrous cycle of albino and normally pigmented mice were examined. The oestrous cycle of both types of mice was shorter at the lower intensity but the difference was significant only with the black mice. The proportion of albino mice from which embryos were recovered was significantly smaller than the proportion of black mice at 15-20 lux but not at 220-290 lux. No significant differences due to strain or light intensity were found in the number of embryos recovered. We conclude that pigmented mice respond in the same way as albino mice to changes in light intensity within the range normally found in laboratory animal accommodation. That is, increased light intensity prolongs the oestrous cycle and the period of vaginal cornification.
Chondroma of the foreleg in a Syrian hamster
Authors: Brown Peter , Henderson Julian , Hilton Tamsin , Parren John
Published: May 2007

A spontaneous bone tumour in the foreleg of a Syrian hamster was shown to be a chondroma; this is only the second report of such a tumour and the first described in detail.
Reduced tumour incidence in mice with inherited seborrhoeic dermatitis
Authors: Höger Harald , Gialamas Jordane , Adamiker Dieter
Published: May 2007

121 mice homozygous for the gene seb (inherited seborrhoeic dermatitis) and their 142 unaffected heterozygous littermates were kept for their natural lifespan. Heterozygotes showed 84.1% total tumour incidence in males and 95.9% in females. The most common neoplasms were lymphomas, osteomas, lung tumours and neoplasms of the female genital tract. Homozygotes showed a tumour incidence of 36.1 % in males and 45.0% in females. The reduction in incidence included all types of neoplasms except epithelial tumours of the skin: skin tumours were detected in 11 homozygous but only in one heterozygous animal. Life expectancy was not affected significantly by genotype. Homozygous mice showed rough and greasy fur and became alopecic with age. Energy intake was increased but growth and depository fat was reduced compared with heterozygous mice. Higher heat loss may incompletely be compensated by higher metabolic rate and thus 'dietary restriction' results in decreased tumour rates. As females show small gonads and a higher increase in food consumption hormonal factors may also be involved.
Ornithine decarboxylase, fatty acid synthetase, and lipid levels in selected organs of the postnatal developing male miniature pig
Authors: Gaines Dennis W. , Friedman Leonard , Newell Richard F. , Matthews Roger N. , Sager Arlen O. , Braunberg Robert C. , Henderson Glen R.
Published: May 2007

Ornithine decarboxylase (ODC) and fatty acid synthetase (FAS) activities were determined in tissues from male neonate and juvenile miniature swine (Hormel-Hanford strain) at various ages. ODC activity was measured in liver, brain, kidney, pancreas, and spleen at one day and at 1, 4, 8, 12 and between 24 and 32 weeks. Hepatic FAS activity, total lipid, triglyceride, and total cholesterol were measured at 2, 8, 16, and 32 weeks. Generally, tissue ODC activity was highest in the spleen at all ages. Three postnatal patterns of ODC activity were observed for the different organs. The mean values of FAS activity, total lipid, and cholesterol were highest at 8 weeks compared to other sampling periods.
Transmission of murine viruses and mycoplasma in laboratory mouse colonies with respect to housing conditions
Authors: Homberger Felix R. , Thomann Peter E.
Published: May 2007

Pathogen-free sentinel mice were placed in 7 animal rooms with different housing conditions and were serologically screened for antibodies to mouse hepatitis virus (MHV), pneumonia virus of mice (PVM), Sendai virus, reovirus 3, Theiler's mouse encephalomyelitis virus (TMEV), ectromelia virus and Mycoplasma pulmonis by enzyme-linked immunosorbent assays, at intervals after introduction. The most commonly detected antibody was against MHV, which was found in mice from 4 rooms, followed by PVM antibody in mice from 3 rooms. Seroconversion to Sendai virus and TMEV was detected in mice from one room each. No seroconversion to any of the antigens was found in 2 rooms. The common criteria of these 2 rooms were that they housed pathogen-free animals from a single source and that the access to the rooms was, purposely or not, restricted to people who had no contact to other mice. The study demonstrated the importance of husbandry and hygienic regimen on the prevalence of infectious agents in laboratory mice.