bluuebunny/crossref_metadata_2025 huggingface dataset:
Blood transcriptome analysis: Ferroptosis and potential inflammatory pathways in post-traumatic stress disorder
Authors: Zhu Jie , Zhang Ye , Ren Rong , Sanford Larry D. , Tang Xiangdong
Published: October 2022

Background

Transcriptome-wide analysis of peripheral blood in post-traumatic stress disorder (PTSD) indicates widespread changes in immune-related pathways and function. Ferroptosis, an iron-dependent regulated cell death, is closely related to oxidative stress. However, little is known as to whether ferroptosis plays a role in PTSD.

Methods

We conducted a comprehensive analysis of combined data from six independent peripheral blood transcriptional studies in the Gene Expression Omnibus (GEO) database, covering PTSD and control individuals. Differentially expressed genes (DEGs) were extracted by comparing PTSD patients with control individuals, from which 29 ferroptosis-related genes (FRGs) were cross-matched and obtained. The weighted gene co-expression network analysis (WGCNA), the Extreme Gradient Boosting (XGBoost) model with Bayesian Optimization, and the least absolute shrinkage and selection operator (LASSO) Cox regression were utilized to construct a PTSD prediction model. Single-sample Gene Set Enrichment Analysis (ssGSEA) and CIBERSORT revealed the disturbed immunologic state in PTSD high-risk patients.

Results

Three crucial FRGs (ACSL4, ACO1, and GSS) were identified and used to establish a predictive model of PTSD. The receiver operating characteristic (ROC) curve verifies its risk prediction ability. Remarkably, ssGSEA and CIBERSORT demonstrated changes in cellular immunity and antigen presentation depending on the FRGs model.

Conclusion

These findings collectively provide evidence that ferroptosis may change immune status in PTSD and be related to the occurrence of PTSD, which may help delineate mechanisms and discover treatment biomarkers for PTSD.
Improved emotion regulation following a trauma-informed CBT-based intervention associates with reduced risk for recidivism in justice-involved emerging adults
Authors: Dumornay Nathalie M. , Finegold Katherine E. , Chablani Anisha , Elkins Lili , Krouch Sotun , Baldwin Molly , Youn Soo Jeong , Marques Luana , Ressler Kerry J. , Moreland-Capuia Alisha
Published: October 2022

Objective

Male youth who have been involved in the juvenile legal system have disproportionate rates of trauma and violence exposure. Many justice-involved youth have untreated mental illness, with an estimated 66% of young men who are incarcerated meeting criteria for at least one mental health disorder, including posttraumatic stress disorder (PTSD), depression, and substance abuse. While Cognitive Behavioral Therapy (CBT) approaches are considered among effective evidence-based treatments for addressing and treating behavioral and emotional difficulties, male youth with a history of incarceration and youth who are at risk for (re)incarceration, violence, emotion dysregulation, and trauma face significant barriers in accessing these services.

Methods

Roca, Inc. (Roca), an internationally recognized organization moving the needle on urban violence by working relentlessly with young people at the center of violence in Massachusetts and Maryland, employs a trauma-informed CBT-based skills curriculum and approach in their intervention model, to improve youths' educational, employment, parenting, and life skills opportunities, while decreasing risk for recidivism, addressing trauma and increasing skills for emotion regulation. The aim of this analysis was to assess the effectiveness of Roca's trauma-informed CBT skills curriculum on youths' emotional and behavioral outcomes. We analyzed data from over 300 participating emerging adult men from four sites in Massachusetts and one site in Baltimore, Maryland who had at least three series of data collection across multiple skills-based sessions.

Results

We found improvements in outcomes in overall mean scores related to decreased distress about employment and education, as are expected with standard intervention approaches for justice-involved youth. Participants who show improvement in emotion regulation across engagement (approximately half the cohort), were found to have significant improvements in distress related to relationship and family functioning and self-care, and decreased substance use, along with other outcomes compared to those participants with less improvement in emotion regulation. Furthermore, improvement in different aspects of emotion regulation were associated with improved relationships, life distress, substance use, and improved prosocial thinking.

Conclusions

Together, these data suggest that adding mental health support and skills training, such as with trauma-informed CBT models, to programs for justice-involved youth may lead to significant improvements in functioning, quality of life, and mental health outcomes.
Living alone decreased calcaneus ultrasound T-score in a large Taiwanese population follow-up study
Authors: Lin Ting-Yi , Chen Szu-Chia , Geng Jiun-Hung , Tsai Hui-Ju
Published: October 2022

Background

Osteoporosis is associated with many serious health conditions that have a severely negative impact on quality of life, as well as higher rates of morbidity and mortality. Due to the aging society and low birth rate in Taiwan, an increasing number of people are living alone. This longitudinal study was aimed to assess the relationship between living alone and calcaneus ultrasound T-score in a large cohort in Taiwan.

Methods

A total of 118,853 participants enrolled in the Taiwan Biobank since 2008 to 2016, who had complete calcaneus ultrasound examinations were collected in the baseline study. Of these participants, 26,850 received complete follow-up measurements after a median of 4 years. The T-score (g/cm2) of the calcaneus in the non-dominant foot was measured using ultrasound. Changes in the calcaneus ultrasound T-score (ΔT-score) were calculated as follow-up T-score minus baseline T-score. We analyzed these data in 2022. We used multivariable linear regression analysis to investigate correlation between living alone with baseline T-score and ΔT-score. We also carried out separate analyses for men and women.

Results

The mean age of the participants was 49.89 ± 10.95 years, and multivariable analysis showed that living alone was significantly correlated to low baseline T-score in whole cohort (β = −0.040; p = 0.012) and women (β = −0.055; p = 0.023). Furthermore, living alone (coefficient β = −0.049; p = 0.048) was significantly correlated to a low ΔT-score after 4 years of follow-up.

Conclusion

In this large population-based longitudinal study, living alone may be related to low baseline calcaneus ultrasound T-score and ΔT-score. Adopting long-term community-based care policies to increase the activity of people living alone may help to prevent osteoporosis and decrease the risk of fractures in Taiwan.
A cross-sectional study to assess the level of satisfaction with virtual education in Peruvian medical students
Authors: Grados-Espinoza Pamela , Zila-Velasque J. Pierre , Soriano-Moreno David R. , Regalado-Rodríguez Kateriny Margot , Sosa-Nuñez Frank , Barzola-Farfán William , Gronerth Jim , Guizado Lucia , Mejia Christian R.
Published: October 2022

Objectives

Education has totally changed in the context of the pandemic. Therefore, the objective of the present study was to evaluate the factors associated with the level of satisfaction with virtual education in Peruvian medical students during COVID-19.

Methods

Analytical and cross-sectional study, based on an online survey of students nationwide. We use previously validated instruments to measure the level of satisfaction and stress (EPP-10-c) of students with virtual education. For the associated factors, adjusted prevalence ratios (PR) were estimated using Poisson regression.

Results

Of the 1,878 students surveyed, the median age was 21 years, 57.8% (1,086) were women, 34.8% (654) had a high level of satisfaction with virtual education and 10.7% (202) presented high levels of stress. The factors associated with a low level of satisfaction were attending the fifth year of study, the partial and non-virtual adaptation of the university to virtual education, and a high level of stress. On the other hand, the factors associated with a high level of satisfaction were the education platform used and the study method used.

Conclusion

Seven out of 10 students presented a low level of satisfaction with virtual education, 1 out of 10 presented a high level of stress. The factors associated with the low level of satisfaction were attending the fifth year of study, the non-virtual and partial adaptation of the university to virtual education, and the high level of stress.
Walking and taking vitamin C alleviates oxidative stress and inflammation in overweight students, even in the short-term
Authors: Zhang Qian , Guo Miao , Chen Tianyi , Cheng Huizhi , Yang Qianwen , Zhao Zhuohui , She Rong , Yang Xiaoyan , Xiao Wen , Yang Xu , Li Lijuan
Published: October 2022

Objective

Obese or overweight is a risk factor for some chronic diseases, and oxidative stress and inflammation may be one of the molecular mechanisms leading to the persistence of these chronic diseases. Discovering interventions to alleviate oxidative stress and inflammation in the overweight/obese population, is very important for public health and health education.

Methods

A two-week panel intervention study (Run 0-Run 1-Run 2) was conducted. The subjects were 77 overweight/obese undergraduates attending Dali University, with a BMI>24 kg/m2. The physical indices measured at the end of each run included BMI, waist circumference, serum ROS, TNF-α, IL-1β and urinary 8-OHdG. Students were allocated to one of four intervention groups: No intervention (control); walking; taking vitamin C; and walking + taking vitamin C.

Results

The results demonstrated (1) Walking significantly alleviated ROS levels, and this was consistent in Run 1 and Run 2; (2) During Run1, all three intervention modes reduced levels of 8-OHdG, but there was a statistically insignificant increase during Run 2; (3) No alleviating effects of the three intervention modes on TNF-α levels during Run 1 and Run 2 were observed; (4) The alleviating effects of the three intervention modes on IL-1β levels during Run 1 and Run 2 were clear.

Conclusion

Walking and taking vitamin C can reduce levels of ROS, 8-OHdG and IL-1β, but not TNF-α, in overweight/obese participants. These interventions may become potential preventive measures for the overweight against obese-induced oxidative stress and inflammation.
Uptake of COVID-19 booster shot among healthcare workers: A mediation analysis approach
Authors: Rehman Shazia , Rehman Erum , Jianglin Zhang
Published: October 2022

Since the thrust of previous research investigations has been on people's willingness to get immunized against the COVID-19 infection, the underpinning principle of compliance has received very little attention. Addressing the possible drivers and mechanisms influencing vaccine acceptance may provide significant insights for limiting the pandemic. In response, we intend to investigate the influence of decision regret and the consequences of post-vaccination adverse effects on the inclination to undertake booster shots. An electronic survey that was self-administered was conducted in Rawalpindi, Pakistan. The questionnaire was completed by 1,369 participants, with a response rate of 41%. 1,343 of them (98.10%) had received both doses of the COVID-19 vaccination. Besides, the present research has also adopted a mediation model. Our findings demonstrate that unfavorable vaccination responses in healthcare workers significantly affect their likelihood of receiving booster shots. Interestingly, healthcare workers who had adverse experiences after being immunized were more prone to regret their prior immunization decisions, which in response affected their decision to get a booster shot. The motivation to receive the booster dosage and adverse post-vaccination responses were mediated by decision regret. The outcomes suggested indissociable connections between unfavorable vaccination responses, decision regret, and the likelihood of receiving a booster shot. To strengthen immunization acceptance intent and enhance the likelihood of receiving COVID-19 booster shots, it is recommended that awareness of these post-vaccination adverse events be extensively integrated into immunization awareness programs and policy measures supporting booster doses.
Breast awareness mobile apps for health education and promotion for breast cancer
Authors: Yusuf Azlina , P. Iskandar Yulita Hanum , Ab Hadi Imi Sairi , Nasution Arryana , Lean Keng Soon
Published: October 2022

Background

Lack of knowledge, poor awareness, and attitude are barriers to breast cancer (BC) screening participation. The ubiquitous usage of mobile phones makes it a perfect platform for delivering interventions to increase knowledge and awareness in screening, a strategy for early identification of BC. However, although numerous applications for BC prevention are available on major mobile phone platforms, relatively few have been tested in scientific studies to determine their efficacy.

Objective

This study aimed to assess the efficacy of BrAware Apps in increasing the knowledge of BC risk factors, awareness of warning signs and confidence in breast self-examination (BSE) among women in northeast peninsular Malaysia.

Methods

A quasi-experimental pre and post-test research design were conducted with 41 women participants in Kelantan, Malaysia, before and after using the BrAware apps. Participants were given an online, adapted Breast Cancer Awareness Measure questionnaire. Post-test was 2 months after using the BrAware apps. Comparison using paired T-tests were conducted to evaluate the change in knowledge of risk factors, warning signs awareness and confidence level for BSE.

Results

The mean age of women was 39.71(SD = 8.80). The participants' mean knowledge score of BC warning signs differs before using BrAware (mean 70.62, SD 11.74) and after using the BrAware app (mean 79.83, SD 10.15) at the <0.001 level of significance.

Conclusions

The BrAware mobile app had a positive effect in increasing the women's knowledge of risk factors of BC, warning signs awareness and confidence level for BSE. It can be concluded that the mobile app may be an adjunct in educating women on BC.
“Blood lead level among battery factory workers in low and middle-income countries: Systematic review and meta-analysis”
Authors: Olana Ararso Tafese , Kumie Abera , Abegaz Teferi
Published: October 2022

Introduction

Lead is one of the most health-hazardous causes of acute and chronic poisoning at workplaces. A limited study was conducted on the blood lead concentration among battery factory workers in low and middle-income countries. Therefore, this study will improve workplace health and safety conditions of workers in this sector and serve as baseline data for further studies in this segment of the working setup.

Objective

This review aims to identify the pooled mean blood lead level among battery factory workers in low and middle-income countries.

Methods

The search methods considered the following electronic bibliographic databases: google scholar, PubMed, and other gray literature. A funnel plot and Begg test were used to see the publication bias. The heterogeneity of studies was checked using I-square statistics with a cut of point 75% and the Joanna Briggs Institute (JBI) quality assessment tool was applied to ensure the quality of the included articles. A random-effect model was applied to pool the blood lead level intoxication. The sub-group analysis and Meta-regression analysis were conducted by country and year of publication to control heterogeneity and to show variation. We included the articles published from 2000 to 2021 year in the English language.

Results

Through the search strategies, 135 articles were identified and 43 full-text articles were selected for evaluation, and finally, eighteen (18) articles fit the inclusion criteria. From the 18 studies included in the meta-analysis, the mean pooled blood lead level of workers was 37.996 μg/dl (95% CI: 30.680–45.312) which is higher than the threshold limit value set by American conference of governmental industrial hygienists (20 μg/dl). In subgroup analysis by year in the random effect model, the pooled mean of blood lead level from 2006 to 2011= 43.20 μg/dL (35.91–50.50), 2012–2015 = 37.78 μg/dl (25.23–50.29), and 2016–2020 = 36.53 μg/dl (19.44–53.62).

Conclusions

This review showed that the pooled mean blood lead level of workers exposed to lead battery factories was (37.996 μg/dl) which is above the threshold limit value (20 μg/dl). Therefore, attention should be given by employers, government, and researchers to improve the health of working populations exposed to lead exposure in low and middle-income countries through the provision of occupational health and safety services like periodical medical checkups, treatments, and provision of training and adequate and appropriate personal protective equipment.

Systematic review registration: Identifier: CRD42022322827.
High prevalence of obesity among women in urban Haiti: Findings from a population-based cohort
Authors: Dade Eliezer , Metz Miranda , Pierre Jean Lookens , Rouzier Vanessa , Sufra Rodney , Fox Elizabeth , Preval Fabyola , St-Preux Stephano , Zephir Jean Ronald , Ariste Wilson , Rasul Rehana , Sabwa Shalom , Roberts Nicholas , Deschamps Marie Marcelle , Severe Patrice , Fitzgerald Daniel , Pape Jean William , Yan Lily Du , McNairy Margaret L.
Published: October 2022

Introduction

Obesity is associated with increased risk of non-communicable diseases and death and is increasing rapidly in low- and middle-income countries, including Haiti. There is limited population-based data on body mass index (BMI) and waist circumference (WC) and associated risk factors in Haiti. This study describes BMI and WC, and factors associated with obesity using a population-based cohort from Port-au-Prince.

Methods

Baseline sociodemographic and clinical data were collected from participants in the Haiti CVD Cohort Study between March 2019 and August 2021. Weight was categorized by BMI (kg/m2) with obesity defined as ≥30 kg/m2. Abdominal obesity was defined using WC cutoffs of ≥80 cm for women and ≥94 cm for men based on WHO guidelines. Sociodemographic and behavioral risk factors, including age, sex, educational attainment, income, smoking status, physical activity, fat/oil use, daily fruit/vegetable consumption, and frequency of fried food intake were assessed for their association with obesity using a Poisson multivariable regression.

Results

Among 2,966 participants, median age was 41 years (IQR: 28–55) and 57.6% were women. Median BMI was 24.0 kg/m2 (IQR: 20.9–28.1) and 508 (17.1%) participants were obese. Women represented 89.2% of the population with BMI ≥30 kg/m2. A total of 1,167 (68.3%) women had WC ≥80 cm and 144 (11.4%) men had WC ≥94 cm. BMI ≥30 kg/m2 was significantly more prevalent among women than men [PR 5.7; 95% CI: (4.3–7.6)], those 40–49 years compared to 18–29 years [PR 3.3; 95% CI: (2.4–4.6)], and those with income >10 USD per day compared to ≤1 USD [PR 1.3; 95% CI: (1.0–1.6)]. There were no significant associations with other health and behavioral risk factors.

Discussion

In Haiti, women have an alarming 6-fold higher obesity prevalence compared to men (26.5 vs. 4.3%) and 89.2% of participants with obesity were women. Abdominal obesity was high, at 44.3%. Haiti faces a paradox of an ongoing national food insecurity crises and a burgeoning obesity epidemic. Individual, social, and environmental drivers of obesity, especially among women, need to be identified.
Faculty perspectives on a collaborative, multi-institutional online hydrology graduate student training program
Authors: Jefferson Anne J. , Loheide Steven P. , McCay Deanna H.
Published: October 2022

The CUAHSI Virtual University is an interinstitutional graduate training framework that was developed to increase access to specialized hydrology courses for graduate students from participating US institutions. The program was designed to capitalize on the benefits of collaborative teaching, allowing students to differentiate their learning and access subject matter experts at multiple institutions, while enrolled in a single course at their home institution, through a framework of reciprocity. Although the CUAHSI Virtual University was developed prior to the COVID-19 pandemic, the resilience of its online education model to such disruptions to classroom teaching increases the urgency of understanding how effective such an approach is at achieving its goals and what challenges multi-institutional graduate training faces for sustainability and expansion within the water sciences or in other disciplines. To gain faculty perspectives on the program, we surveyed (1) water science graduate program faculty who had served as instructors in the program, (2) water science graduate program faculty who were aware of the program, but had not participated, and (3) departmental chairs of participating instructors. Our data show widespread agreement across respondent types that the program is positive for students, diversifying their educational opportunities and increasing access to subject matter experts. Concerns and factors limiting faculty involvement revolved around faculty workload and administrative barriers, including low enrollment at individual institutions. If these barriers can be surmounted, the CUAHSI Virtual University has the potential for wider participation within hydrology and adoption in other STEM disciplines.
The squeaky wheel gets the grease: Violent civil unrest and global social assistance provision
Authors: Çemen Rahmi , Yörük Erdem
Published: October 2022

What are the contemporary determinates of social assistance provision? What is the role of contentious politics? Social assistance literature is dominated by economic and demographic accounts, which under-examine the possibility that governments extend social assistance to contain social unrest. We test factors associated with these “structuralist” and “political” theories on a new panel dataset which includes 54 OECD and emerging market countries between 2002 and 2015. The results indicate social assistance coverage has a significant positive relationship with riots. We explain this outcome as policymakers expanding social assistance as a means of containing violent civil unrest. This effect is more significant in emerging markets, suggesting that the domination of structural explanations is a result of sample bias toward the OECD. Finally, we find that governments consider World Bank social policy recommendations only insofar as there is violent unrest.
Global investment gap in agricultural research and innovation to meet Sustainable Development Goals for hunger and Paris Agreement climate change mitigation
Authors: Rosegrant Mark W. , Sulser Timothy B. , Wiebe Keith
Published: October 2022

This paper provides estimates of the global investment gap in agricultural research and development (R&D) and innovation. The investment gap is defined as the additional annual investments required to end hunger in 2030 (Sustainable Development Goal SDG2) and to put agriculture on the pathway to the Paris Agreement target for 1.5°C increase over pre-industrial temperature levels. The investment gap is projected relative to a reference scenario with projections to 2030 using an integrated economic-biophysical model of the global agri-food system. In addition to showing the impacts on hunger, the modeling results are used to simulate the effect of the gap-closing investments on greenhouse gas (GHG) emissions from agriculture. In addition to projecting the impacts of overall investment in agricultural R&D on productivity and environmental outcomes, the analysis assesses the contributions of different types of innovative technologies and farming systems to the environmental outcomes, especially technologies that contribute to sustainability outcomes. Sustainability-oriented technologies and management practices examined include conservation tillage, nitrogen-use efficiency, improved livestock management, and other climate-smart technologies. The projected results show that additional agricultural R&D investments of USD 4 billion per year above baseline investments together with USD 6.5 billion per year invested in technical climate-smart options, can reduce hunger to 5% globally and achieve 2030 GHG emission reductions consistent with the Paris Agreement 2°C and 1.5°C pathways to 2030.
Conocimiento del uso de hierbas y especias en la culinaria otavaleña, con enfoque hacia el marketing gastronómico
Authors: Guevara Aroca Francisco Xavier , Buenaño Allauca Mónica , Villarreal Martínez Bryan Manuel , Herrera Eguez Carolina
Published: October 2022

Se realizó un estudio dirigido a establecer el estado actual del conocimiento local sobre el uso de hierbas y especias en la gastronomía del pueblo indígena kichwa Otavalo, Provincia de Imbabura, Ecuador. Además, identificar el vínculo entre este conocimiento y las acciones que se podrían establecer en un marketing gastronómico más asertivo. A través de un inventario acerca de las especias encontradas cuya información fue analizada mediante la matriz etnobotánica IVIER y clúster, y una revisión de bibliografía especializada en marketing. Esta investigación contiene dos partes bien diferenciadas, una consiste en la investigación de hierbas y especias en la gastronomía local, la otra parte que reside en la revisión de la literatura especializada para sugerir diferentes acciones de marketing que pueden adoptar empresarios del sector turístico, gastronómico y de marketing.
Evaluación de las competencias organizacionales de dos pequeñas y medianas empresas avícolas de la zona norte de Manabí
Authors: Vélez Ganchozo Jessica Viviana , Bravo Macías Columba Consuelo , Félix López Miryam Elizabeth , Murillo Cedeño Silvia Patricia
Published: October 2022

Este trabajo investigativo tuvo como objetivo evaluar las competencias organizacionales previamente identificadas en las micro, pequeñas, medianas y grandes empresas de la zona norte de Manabí: caso Avícola Marcos Vivanco y Avícola Burgos Zambrano con la finalidad de aportar a la mejora de la gestión organizacional. La investigación se realizó bajo un enfoque cuali-cuantitativo, con el que se transformaron las cualidades extraídas del tema objeto de estudio en valores fáciles de interpretar, luego del respectivo tratamiento de los datos; para recabar información referente al tema se utilizó el análisis bibliográfico y a través los métodos inductivo y deductivo se generaron criterios de valor, aplicando las técnicas de la encuesta y la entrevista y, como herramienta, el sistema informático SPSS. Mediante los resultados se denota que: Avícola Marcos Vivanco de las seis competencias, calidad al trabajo con el 22% es la menos desarrollada y orientación al cliente con un 33% posee el mayor nivel de desarrollo; en la Avícola Burgos Zambrano se evaluaron cinco competencias, de las cuales, compromiso con un 28% es la competencia con menor nivel real de desarrollo y orientación a los resultados con un 50% es la más afianzada; por tanto, las competencias organizacionales de las MIPYMES objeto estudio, no se encuentran totalmente desarrolladas como se requiere. Finalmente, se concluye que la carencia de estudios de la gestión organizacional direccionados a las competencias en este sector, impide complementar los resultados con un análisis histórico de la evaluación, aportándole mediante este estudio a mejorar las condiciones técnicas operativas y de gestión.
Procedimientos tributarios en la compañía Libertadores Libertaxis S.A. de Riobamba, Ecuador
Authors: Castillo Moya Viviana Aracely , Santillán Silva Myriam de los Angeles
Published: October 2022

La presente investigación tiene como objeto establecer los procedimientos para el cumplimiento de las obligaciones tributarias de la compañía Libertadores Libertaxis S. A. de la ciudad de Riobamba (Ecuador).Esta investigación es de tipo documental puesto que se basa en la Ley Orgánica de Régimen Tributario Interno (LORTI) y el Código Tributario, el diseño que se aplicó es no experimental con un enfoque de campo, los métodos de investigación fueron deductivo, inductivo y analítico, las técnicas que se utilizaron fueron de observación directa; una vez establecidas las fechas máximas de presentación de sus deberes se establecieron flujogramas para la elaboración de las declaraciones y anexos requeridos; los resultados esperados con el cumplimiento de estos procedimientos será evitar el pago innecesario de multas y aportarán con cultura tributaria así como en la disminución de evasión existente en nuestra sociedad.
Análisis de los costos asociados a la calidad en comercializadora de tabaco
Authors: Naranjo Naranjo Aniel , Bravo Amarante Edelvis , Quintero Rodríguez Dairon
Published: October 2022

La presente investigación se realiza en la Unidad Empresarial de Base División Centro Este ubicada en la ciudad de Sancti Spíritus, el objetivo general es aplicar un procedimiento que permita el análisis de los costos asociados a la calidad y facilite la toma de decisiones, orientadas a la mejora de la calidad de los procesos. En el cumplimiento del objetivo se identifican los problemas de no calidad en uno de sus procesos claves, tomado como caso de estudio. Para la investigación se propone un procedimiento de análisis de costos de calidad, que cuenta con ocho etapas que se dividen en tres fases. Con la aplicación se logra la identificación y clasificación de los costos de calidad, sobre la base del criterio de expertos, otorgándoles niveles de importancia y facilitar el proceso de toma de decisiones. Se identifican los fallos y las causas que lo originan. Los fallos internos representaban el 5,3% y los fallos externos 7,8%, de los costos totales de calidad, haciendo énfasis en los fallos y las causas que los originan, aspecto que permitió, reducirlos a niveles de poca relevancia de un trimestre con respecto al otro.
Turismo y desarrollo local en el litoral ecuatoriano. Potencialidad y límites: Crucita, Ecuador
Authors: Sabando Cedeño Erick Fabian , Amat Montesinos Xavier , Ruiz Cedeño Angélica Beatriz
Published: October 2022

La investigación ha sido desarrollada en la cabecera parroquial de Crucita (Portoviejo). El objetivo es identificar las principales limitaciones y potencialidades turísticas de la playa de Crucita, además de explorar el alcance de las prácticas de desarrollo local sostenible por parte de las administraciones públicas y privadas. La investigación se plantea si el modelo de turismo de masas implantado en Crucita podría haberse agotado y si sería necesaria una transformación. Para abordar lo mencionado, se han empleado los métodos de análisis-síntesis, deductivo-inductivo, histórico-lógico y el estadístico. Los resultados demuestran que la cabecera parroquial de Crucita posee gran capacidad de alojamiento y un potencial de empleabilidad de carácter local. Este destino ha reportado un fuerte crecimiento en flujos de visitas en los últimos años que, acompañado de las acciones administrativas adecuadas, podrían hacer del turismo un importante activo para el desarrollo local sostenible.
Gestión de proyectos en sistemas de agua potable: Evaluación de modelos implementados en Manabí
Authors: García Urdánigo Jonathan Paúl , Mieles Bravo Yordi , Quiroz Fernández Santiago
Published: October 2022

El presente artículo analiza la gestión de proyectos como una herramienta fundamental para el desarrollo, donde una buena implementación de esta actividad permite la obtención oportuna de créditos financieros. El objetivo del mismo es realizar una evaluación de los modelos de gestión de proyectos de agua potable implementados en la provincia de Manabí, para lo cual se utilizaron diferentes instrumentos como la entrevista en profundidad, el análisis de la documentación entregada en la gestión por parte del Gobierno Autónomo Descentralizado (GAD) Municipal del cantón Pichincha y la aplicación de evaluación de madurez en la gestión de proyectos mediante Organizacional Project Management Maturity Model (OPM3). Los resultados indicaron que no se cuenta con un modelo estandarizado, con un nivel de madurez gestionado; siendo indispensable aplicar este tipo de evaluación en otros municipios e instituciones públicas, lo que permitirá tener una perspectiva real de los modelos de gestión utilizados actualmente.
Action of Carbofuran Technical on Tissue Lipids of Freshwater Catfish, Heteropneustes fossilis (Bloch)
Authors: GHOSH R.
Published: October 2022

Female catfish (Heteropneustes fossilis, Bl.) were exposed to sublethal doses of carbofuran technical pesticide (0.5, 1.0 and 2.0 mg/I) for 30 days during the prespawning phase of the annual reproductive cycle (May-June) .. Cholesterol, total lipid and its fatty acid contents were determined in the liver and in the ovary. Cholesterol and total lipid increased significantly in the liver but remained unchanged in' the ovary. This is an indication of the inhibitory effect of carbofuran on the mobilization of hepatic cholesterol and total lipid. In both organs, the predominant fatty acids in total lipid were palmitic (C16:0),palmitolic (C16:1), stearic (C18:0), oleic (C18:1), linoleic (C13:2), and arachidonic (C20:4), both in the controlled and in the treated fish. However, eicosapentaenoic acid (C20:5), and docosahexaenoic acid (C22:J, were absent among fish receiving high doses of carbofuran. The polyunsaturated fatty acid ratio (w3/w6) was reduced among treated fish in comparison to the controlled ones. It is concluded that the lipid metabolism in catfish is affected by the technical grade of carbofuran.
Environmental Management/Marketing Research: Bibliographic Analysis
Authors: Mohammed Datu , Prawiyog Anggy Giri , Royani Dewi Elisa
Published: October 2022

This study identifies, synthesizes and evaluates existing environmental research marketing and management with the ultimate goal of revealing trends in this area. In particular, we focus on: the methodological aspects of empirical research are the design, scope, and methodology, the field of study covered and the specific issues raised in all regions. Related articles are also identified electronically. Manual bibliographic search method. A total of 530 articles from 119 scientists were identified in magazines published from 1969 to 2008. Each article is analyzed with 6 pieces of content: key aspects: author profile, manuscript characteristics, study design, scope research, research methodology and field of study. Overall, this research facility is facing serious problems. Transformation moves from the early stages of identification and discovery to more advanced stages, an advanced stage characterized by greater maturity and rigidity. This is indicated by: trends towards inter-author, intercultural and interdisciplinary collaboration. The length of the manuscript and the number of references increased over time. Grow up maturity of study design with increasing emphasis on formalization and causality structure; various countries, industries, Products and companies of varying status, size, and geographic focus. The tendency to use stochastic sampling designs to achieve high response rates, ensuring large sample sizes, Apply advanced statistical analysis. Wide variety and deep coverage examining the topic.
Implementation of Competence-Based Human Resources Management in the Digital Era
Authors: Dolan Ellen , Kosasi Sandy , Sari Siti Nurindah
Published: October 2022

Human resource management digitization may help businesses update their HR processes and provide them a competitive edge. At the same time, it demands a change in work style and a change in the necessity for Human Resources. The purpose of the study is to determine how competency-based human resource management may be used in the digital age. Additionally, researchers examine the primary advantages and disadvantages of the present situation and examine how they affect the skills and roles of HR professionals. Analysis of secondary data characterizing the degree of current digital proficiency based on the responses of more than 7,000 respondents from six EU member nations is part of the qualitative research (Germany, Finland, UK, Portugal, Sweden and Slovakia). The findings show that professional HR applications are typically hesitant to incorporate new technology. Future scholars should note that this study solely focuses on how human resource management is used in the digital age. Therefore, further in-depth study on this issue may be carried out by choosing a larger focal area.
Richard Taruskin and Us
Authors: Ковнацкая Людмила
Published: October 2022

Это эссе - попытка запечатлеть Ричарда Тарускина таким, как его помнит автор: не только блестящим ученым, но и замечательным человеком.

This essay attempts to capture Richard Taruskin as the author remembers him: not only a brilliant scientist but also a wonderful person.
In Memory of Professor Taruskin
Authors: Савенко Светлана
Published: October 2022

Некролог посвящен памяти Ричарда Тарускина (1945-2022) - ключевой фигуры современного музыковедения. В тексте даются выдержки из биографии ученого, а также цитаты из переписки с автором.

This obituary is dedicated to the memory of Richard Taruskin-the key figure of modern musicology. The text gives excerpts from the biography of Taruskin, as well as fragments from correspondence with the author.
“The Bach Bow”: An Ingenious Discovery or a Beautiful Legend?
Authors: Текучева Алеся
Published: October 2022

В статье идет речь о так называемом баховском смычке. Еще в эпоху романтизма музыканты задавались вопросом, каким образом нужно играть полифонические сочинения И. С. Баха для скрипки соло: возможности инструмента не позволяли исполнять все звуки аккорда в соответствии с длительностями, указанными в нотном тексте. В начале XX века А. Шеринг пришел к мысли, что во времена Баха существовал смычок иной конструкции, предполагавший звучание на скрипке протянутых аккордов. Теорию Шеринга горячо поддержал А. Швейцер, включив описание смычка в свою монографию о Бахе. По мнению ученых, знаменитые сонаты и партиты для скрипки соло композитор сочинил с расчетом именно на такой смычок. Оригинальные идеи музыковедов восприняли скрипачи и, адаптировав теоретически описанную конструкцию к практическому использованию, представили публике столь необычное исполнение произведений Баха. Обращаясь к трактатам XVII-XVIII веков, освещая историю появления и дальнейшего усовершенствования смычка, анализируя качество звучания и неудобства, с которыми сталкиваются скрипачи, а также сопоставляя слышимый результат с рукописным текстом, автор статьи приходит к выводу, что теория, согласно которой в баховскую эпоху существовал особый смычок, безосновательна, а ее практическое применение в барочном исполнительстве, в отличие от современного искусства, вряд ли можно считать оправданным: его использование целесообразно ограничить кругом современных сочинений, авторы которых сознательно ориентируются на возможности разработанного в 1989 году М. Бахом изогнутого смычка.

This article clarifies the phenomenon of the Bach bow. The question of how to play Bach's polyphonic works for solo violin goes back to the era of Romanticism. The design of the standard violin bow makes it incapable of playing simultaneous chords indicated in Bach's scores. Musicologist Arnold Schering first suggested at the beginning of the 20th century that there had been a special bow with a widely-curved wood piece to play all four strings of the violin simultaneously. Albert Schweitzer supported this new theory and described Bach bow construction in his monograph. According to these musicologists, Bach's famous violin solo sonatas and partitas were composed specifically for this type of bow. Violinists accepted these ideas and made the transition from the theoretical model of the curved bow to performing practice possible. After analysing several treatises of the 17th-18th centuries, the history and development of the Bach bow, sound quality as well as the inconveniences faced by the violinists and also after comparing the audible result with Bach's manuscripts, the author of this article proves the Bach bow theory to be unfounded and the Bach bow itself inappropriate for performing baroque music-in contrast to modern art: it would be appropriate to restrict the use of this device to the range oF modern compositions whose authors consciously focus on the possibilities of the curved bow developed in 1989 by M. Bach.
Music and Poetry in Dialogue: Pauline Viardot and Ivan Turgenev
Authors: Редепеннинг Доротея
Published: October 2022

В статье рассматриваются песни Полины Виардо, имеющие несколько вариантов текста на разных языках; определяется роль, которую сыграл Иван Тургенев в композиторском творчестве певицы, а также обосновывается гипотеза о влиянии музыки Виардо на выполненные для нее Тургеневым поэтические переводы. В качестве необходимого контекста излагается информация о художественном кружке, сложившемся в Баден-Бадене в 1860-е годы вокруг семьи Виардо и Тургенева, а также об изданиях песен Виардо в России, Германии и Франции. Специфические требования Тургенева к переводу текстов песен выясняются путем анализа его переписки с Фридрихом фон Боденштедтом. Заключительный раздел статьи содержит подробный разбор взаимодействия музыки и слова в двух песнях Виардо: «Синица» на стихи Тургенева и «In der FrChe» на стихи Эдуарда Мёрике («На заре» в переводе Тургенева). Как показывает автор статьи, Виардо удалось тонкими музыкальными приемами подчеркнуть экзистенциальные глубины стихотворения Тургенева, оставшиеся без внимания его переводчиков на немецкий и французский языки. В то же время Тургенев, переводя миниатюрный шедевр Мёрике, не просто вдохновлялся музыкой Виардо, но принял под впечатлением от нее важные художественные решения, которые помогли ему эксплицировать христианские смыслы, заложенные немецким поэтом, и создать конгениальное оригиналу произведение.

The article examines the songs by Pauline Viardot, which have several versions in different languages, determines the role Ivan Turgenev played in the musical compositions by the singer, and substantiates the hypothesis of the influence of Viardot's music on the poetic translations made for her by Turgenev. As a necessary context, the information is provided about the artistic circle that developed in Baden-Baden in the 1860s around the Viardot family and Turgenev, as well as about the publications of Viardot's songs in Russia, Germany and France. Turgenev's specific requirements for the translation of song lyrics are clarified by analysing his correspondence with Friedrich von Bodenstedt. The final section of the article contains a detailed analysis of the interaction of music and poetry in two songs by Viardot: “The Tit” (“Sinitsa,” in Turgenev's text) and “In der Frühe” by Eduard Mörike (“Na zare,” in Turgenev's translation). As shown by the author, Viardot succeeded in using subtle musical devices to emphasize the existential depths of Turgenev's poem, which were ignored by its translators in German and French. At the same time, when translating Mörike's miniature masterpiece, Turgenev was not only inspired by Viardot's music, but under its influence, he made important artistic decisions that helped him explicate the Christian dimension of the original and create a congenial work.
Adaptive Music in Video Games
Authors: Попов Даниил
Published: October 2022

Музыкальное оформление видеоигр сегодня можно оценивать как феномен, полностью обособленный в самостоятельный жанр. Адаптивная музыка - разновидность игрового саундтрека, ключевой особенностью которой является адаптация звукового сопровождения к тем или иным ситуациям, вызванным действиями игрока. Следует с осторожностью говорить о том, что глубокие теоретические исследования феномена адаптивного саундтрека в настоящий момент отсутствуют и существует проблема его недостаточной изученности в контексте музыкальной теории. Выбор темы обусловлен представлением о рядоположности адаптивной игровой музыки с алеаторными формами. Поскольку классификация техник адаптивного саундтрека на сегодняшний день уже определена и описана в ряде источников, в данной работе будет предпринята попытка дополнить ее соотнесением с существующими классификациями алеаторных форм.

The musical design of video games today can be assessed as a phenomenon completely isolated into an independent genre. Adaptive music is a kind of game soundtrack, the key feature of which is the adaptation of the soundtrack to certain situations caused by the actions of the player. We can say with caution that deep theoretical studies of the phenomenon of adaptive soundtrack are currently lacking, and there is a problem of its insufficient study in the context of musical theory. The choice of the theme is due to the idea of the sequence of adaptive game music with aleatory forms. Since the classification of adaptive soundtrack techniques has already been defined and described in a number of sources, an attempt will be made in this paper to supplement it by correlating it with existing classifications of aleatory forms.
RELAÇÃO ENTRE O IEGM E O PARECER PRÉVIO DAS PRESTAÇÕES DE CONTAS DOS MUNICÍPIOS PELO TCE/RN
Authors: Clara Ismael Rodrigues Maria
Published: October 2022

This study aimed to identify if the Municipal Management Effectiveness Index (IEGM) attributed to the municipalities of Rio Grande do Norte is reflected in the previous opinions issued by the State Court of Auditors (TCE/RN) on the government accounts of these municipalities, as well as to verify if socioeconomic variables of budget superavit of the fiscal year, size of the municipality and volume of revenues explain the final IEGM score and the seven component indexes. For this, data from 158 municipalities were analyzed, referring to fiscal year 2015 - the most recent period with available information on prior opinions. The results showed that there is no association between the IEGM and the probability of a favorable Previous Opinion on the accounts issued by the TCE/RN. This result is influenced by the high number of prior opinions with disapproval of accounts, which makes discrimination difficult. For the same reason, none of the socioeconomic variables cited showed a determining relationship in the issuing of these opinions. In what concerns the IEGM determinants, the estimations carried out revealed that the population size variable presented a relevant value for the Fiscal Management, Protected Cities and Information Technology Governance indexes, and the budget superavit variable presented a determinant value in the Education area. The importance of this study is based on the relevance of the data that the inspection and control mechanisms provide, allowing the analysis of public spending at different levels and in different areas, and promoting a greater participation of the population.