bluuebunny/crossref_metadata_2025 huggingface dataset:
The idea of wholeness as a Russian socio-political phenomenon
Authors: Ishutin A.
Published: July 2020

The purpose of this article is to identify the role and significance of the category of wholeness in the Russian socio-political and historical process. Such methods of scientific research as the retrospective method, the comparative method and the hermeneutic method are used in the article. The author of the article claims that in the context of the collapse of the project Modern and the related worldview impasse, the idea of wholeness becomes the most important ideological paradigm, and this paradigm is peculiar to the Russian socio-political, cultural and philosophical sphere. Just in the Russian worldview wholeness is an important unifying component. It is very significant that thinkers out of completely different social backgrounds and completely different political views came to the idea of wholeness. As an example, the author of the article considers the views of the writer and thinker V.F. Odoyevskiy, religious philosopher V.F. Ern and the revolutionary Marxist A.A. Bogdanov. According to the views of V.F. Odoevsky, the basis of a true worldview is the trinity of faith, knowledge and art. Such integrity also determines the socio-political ideal of the writer. According to V.F. Ern, the whole becomes the whole only on the assumption that it is beyond the borders of our world, beyond death and it is a noumenal Being. Cognizing it, humanity can only build a new socio-political ideal. A.A. Bogdanov has come to the conclusion that the task of a genuine political project facing the future is to give an integral concept of man, as well as the science of holistic knowledge — tektology, and then the harmonious development of a new united humanity will begin. The theoretical and practical significance of the article lies in the fact that in the era of social upheaval and the dominance of postmodernism, the idea of wholeness becomes again very relevant because without it any social-political and historical design is impossible.
Artificial Intelligence Phenomenon: Citizen Between Digital Avatar and Political Interface
Authors: Fedorchenko Sergey
Published: July 2020

The aim of the article is to study the features and technologies of artificial intelligence related to the state field and the political sphere of activity of a modern citizen. The methodological basis of the work was the principles of Case Study, comparative analysis. The SWOT analysis was used as another method. The fundamental analytical tool was the principles of the functional approach of Frank Johnson Goodnow, who shared the «state» and «political». The author came to the conclusion that digital rituals are rather contradictory elements of communication - they have both a collective and an individualistic beginning. The main digital phenomena are analyzed. First, a citizen has his own digital avatar - a virtual embodiment of a person, reflecting his image and the most significant characteristic features of his character, individual digital rituals. In addition, non-human digital avatars of the «virtual politician» and «virtual official» appear that are directly related to AI. Secondly, disparate digital avatars can absorb a political interface - a complex of collective and standardized digital rituals that an individual must adhere to if he wants to remain part of a certain political community and network communication space. Secondly, disparate digital avatars can absorb a political interface – a complex of collective and standardized digital rituals that an individual must adhere to if he wants to remain part of a certain political community and network communication space. Thanks to AI, the political interface is able to create a politically determined standardization of the communication functionality offered to users. The thesis is substantiated, according to which the introduction of AI technologies contributes more to expanding control over a citizen than increasing the volume of his political rights. A variety of AI practices in the field of state security, e-government, diplomacy and geopolitics and a relatively small number of AI cases in public policy and party work are revealed.
Living by Others’ Pleasure: Marston, The Dutch Courtesan, and Theatrical Profit
Authors: Munro Lucy
Published: July 2020

We have known for over a century that John Marston held a share in Children of the Queen’s Revels, the all-boy playing company that first performed The Dutch Courtesan in 1604, but how this knowledge affects our understanding of his plays requires further exploration. Drawing on neglected documentary sources, this essay reappraises the company’s links with the Chapel Royal choir to argue that Dutch Courtesan capitalizes on the skills that most clearly connected its performers with the royal choir, even while scrutinizing the ways in which the company turned pleasurable recreation into profit.
Cosmopolitan Desire and Profitable Performance in The Dutch Courtesan
Authors: Fox Liz
Published: July 2020

The Dutch Courtesan reflects on the uses of seduction and desire in commercial culture. The eponymous courtesan Franceschina circulates among foreign clientele; the native conman Cocledemoy accumulates wealth through a range of foreign disguises. Their cosmopolitan appeal to diverse consumers illustrates the dangers of excessive desire linked to an intensifying fashion for foreign commodities in the period. The commodity that is the play itself also capitalizes on similar fascinations of London audiences. Franceschina and Cocledemoy’s explicitly theatrical performances display and satirize how salesmanship – in the form of seduction and trickery – preys on consumer interests to fuel commerce in the global marketplace.
A.D. Cousins and Daniel Derrin, eds. Shakespeare and the Soliloquy in Early Modern English Drama. Cambridge: Cambridge University Press, 2018. Pp. 278.
Authors: Caldicott Joshua
Published: July 2020

This review considers Shakespeare and the Soliloquy in Early Modern English Drama.
De uma discussão para uma investigação (histórica) a partir das aulas de análise real
Authors: Lübeck Kelly Roberta Mazzutti , Lübeck Marcos , Rodrigues Júnior Antônio
Published: July 2020

Este trabalho teve como motivação inicial as discussões acerca do tema numeração provenientes da disciplina de analise real, ministrada no quarto ano do curso de licenciatura em matematica da Universidade Estadual do Oeste do Parana, campus de Foz do Iguaçu. Na ocasião, buscavamos identicar e refletir sobre as principais diferenças entre o conjunto dos números racionais (Q) e o conjunto dos números reais (R); e as considerações a respeito da densidade de Q em R nos levou ao uso da propriedade arquimediana. A simplicidade de seu enunciado e sua relevância na estrutura dos números reais nos conduziu a diversos episódios que extrapolaram a ementa da disciplina, aprofundando os estudos tanto nos aspectos teóricos como nos históricos. Entre eles, buscamos esclarecer a origem do nome que caracteriza tal propriedade, bem como mostrar alguns exemplos e resultados sobre corpos arquimedianos e não arquimedianos.
Hajj health  istithaah  amid the COVID-19 pandemic
Authors: Mansyur Muchtaruddin
Published: July 2020

[No abstract available]
Pre-chirp managed self-phase modulation for efficient generation of wavelength-tunable energetic femtosecond pulses
Authors: Chen Runzhi , Chang Guoqing
Published: July 2020

Self-phase-modulation-enabled spectral selection (SESS) allows generation of widely tunable femtosecond pulses. We propose pre-chirp managed SESS, in which the excitation pulse is properly pre-chirped to control the fiber-optic nonlinear spectral broadening and hence generate separated spectral lobes—a feature demanded by SESS. Besides offering improved efficiency compared with conventional energy-tuned SESS, this new method is able to reshape an input pulse of unwanted shape into a bell-shaped pulse that is desired for implementing SESS. The excellent energy scalability of pre-chirp managed SESS can produce megawatt-level femtosecond pulses widely tunable in the wavelength range of 0.86–1.3 µm. Such a powerful source is well suited to drive multiphoton microscopy to achieve deep-tissue imaging.
Nonlinear beam self-imaging and self-focusing dynamics in a GRIN multimode optical fiber: theory and experiments
Authors: Hansson Tobias , Tonello Alessandro , Mansuryan Tigran , Mangini Fabio , Zitelli Mario , Ferraro Mario , Niang Alioune , Crescenzi Rocco , Wabnitz Stefan , Couderc Vincent
Published: July 2020

Beam self-imaging in nonlinear graded-index multimode optical fibers is of interest for many applications, such as implementing a fast saturable absorber mechanism in fiber lasers via multimode interference. We obtain a new exact solution for the nonlinear evolution of first and second order moments of a laser beam of arbitrary transverse shape carried by a graded-index multimode fiber. We have experimentally directly visualized the longitudinal evolution of beam self-imaging by means of femtosecond laser pulse propagation in both the anomalous and the normal dispersion regime of a standard telecom graded-index multimode optical fiber. Light scattering out of the fiber core via visible photo-luminescence emission permits us to directly measure the self-imaging period and the beam dynamics. Spatial shift and splitting of the self-imaging process under the action of self-focusing are also revealed.
Cultural appropriation: Yours, mine, theirs or a new intercultural?
Authors: Chatterjee Deepsikha
Published: July 2020

This article considers how by shifting culturally anchored design materials from one context to simplistic placement in decontextualized settings, cultural appropriation takes place in costume design. Building on that, it discusses how production teams need to be cognizant of such issues in the design process given that availability of such materials has historically been possible because acquisition has often aligned with political and commercial ambitions. Reviewing scholarship on appropriation that includes performance, costume, fashion and cultural studies, it questions how designing costumes through intercultural interaction might be navigated in a globalized context, where artists are excluded through travel bans, but cultural materials are permitted free movement. The article then discusses how to create productive intercultural projects with teams willing to invest in ethical engagement. By including case studies in which such processes were less successful as well as one that indeed created new intercultural exchanges, this article is one of the first texts to address this complex issue. It intends to engender future forward thinking conversations with practitioners and researchers on the thorny but urgent issue of cultural appropriation through costume.
Digital Design for Custom Textiles: Patterns as Narration for Stage and Film, Amber Marisa Cook (2018)
Authors: Kang Zi Young
Published: July 2020

Review of: Digital Design for Custom Textiles: Patterns as Narration for Stage and Film, Amber Marisa Cook (2018)

New York and London: Routledge, 146 pp.,

ISBN 978-1-13808-417-9, p/bk, £29.99
La participació dels espais rurals en la sostenibilitat ambiental. Anàlisi dels discursos d’iniciatives productives en el context rural de Castelló
Authors: Querol Vicent A. , Ginés Sànchez Xavier
Published: July 2020

Els espais rurals han estat cridats a jugar un paper central en la lluita per pal· liar els efectes del canvi climàtic. La categorització exògena que ha dividit i separat la natura de la societat i la cultura ha tingut efectes negatius sobre la relació entre les poblacions rurals i les institucions que han de vetlar per la sostenibilitat ambiental. Aquest article es planteja l’anàlisi d’iniciatives productives que, des de les àrees rurals de Castelló, hem identificat amb el concepte de Nova Ruralitat i de quina manera els seus discursos harmonitzen amb la sostenibilitat ambiental. L’enfocament teòric revisa un marc on s’exposen les accions del conservacionisme propi de les àrees protegides i del desenvolupament rural, com també les noves concepcions que reforcen els enfocaments que donen veu i valor a les mirades des del rural. I això sense perdre de vista un context institucional supralocal que concentra serveis i infraestructures a les ciutats al temps que genera normatives que segueixen desequilibrant el territori valencià. El bastiment d’una ciutadania rural conscient del canvi climàtic alhora que esperonada a la participació en els processos institucionals esdevé una de les claus d’una sostenibilitat ambiental que ha de recolzar-se sobre una altra sostenibilitat: la social al rural. | Rural areas have been called to play a central role in the fight to mitigate the effects of climate change. The exogenous categorization that has divided and separated nature from society and culture had negative effects on the relation between rural dwellers and the Institutions that supposed to look after environmental sustainability.
Hacia el estudio de megaproyectos turísticos desde la perspectiva de la desterritorialización
Authors: Massé Magaña Mariel Verónica , Vargas Martínez Elva Esther , Palafox Muñoz Alejandro , Zizumbo Villarreal Lilia
Published: July 2020

El capital requiere de nuevos espacios para la preproducción del turismo. La producción primaria es objeto de nuevas fuentes económicas, donde territorios rurales son incorporados a la dinámica productiva de desarrollo urbano. Se analiza, el modelo turístico a partir de una política internacional adoptada por el Estado mediante tres dinámicas: penetración, desterritorialización y acumulación, y su interrelación entre este, el capital turístico y el territorio. Lo anterior permite analizar el modelo turístico hegemónico basado en la creación de megaproyectos, donde las condiciones territoriales son propicias para lograr la acumulación de capital.
A global environmental justice movement: mapping ecological distribution conflicts
Authors: Martínez Alier Joan
Published: July 2020

The industrial economy is not circular, it is entropic, therefore requiring new supplies of energy and materials extracted from the “commodity frontiers”, and producing polluting waste. Therefore, ecological distribution conflicts arise. The Global Atlas of Environmental Justice is an online inventory of such ecological distribution conflicts based on scholarly and activist knowledge. It reached 3200 entries by July 2020 (ejtlas.org) allowing research on such conflicts in the field of comparative, statistical political ecology. The EJAtlas is used for research but also for university teaching in the environmental social sciences and in business economics and management. It is a unique instrument co-produced with and supporting environmental movements. One can do comparative analyses on the social actors involved in the conflicts and their forms of mobilization, and also on the behaviour of private or public companies. Research may focus on countries or regions but also on cross-cultural topics such as gold and copper mining, sand mining, dams, eucalyptus or oil palm plantations, incinerators and other methods of waste disposal, coal fired power plants, gas fracking, nuclear reactors, CAFOs. Analyses are done also on the cross- cultural expressions (slogans, banners, documentaries, murals) of the conflicts gathered in the EJAtlas. The wealth of research coming from the EJAtlas gives an affirmative answer to the question: Is there a global environmental justice movement? Making old or emergent conflicts more visible contributes to placing political ecology at the centre of politics.
La rajola a la costa i els residus a l’interior. Mapa dels conflictes socioecològics al País Valencià
Authors: Faus-Bertomeu Aina , Requena-i-Mora Marina
Published: July 2020

El País Valencià ha vist en la darrera dècada un creixement desmesurat dels processos productius que ha conduït inevitablement a una degradació del territori sense precedents. L’increment de la petjada ecològica, material i de carboni, alhora, ha conduït a la generació de multitud de conflictes socioecològics. Se’n proposa una tipologia dels conflictes socioecològics formada per 5 categories —derivats de processos urbanístics, d’infraestructures, contaminació i salut pública, l’extracció dels recursos minerals i l’ús del recurs hídric—, que els classifica i ubica en el ‘Mapa dels conflictes socioecològics del País València’. El mapa situa territorialment les confrontacions. A més desemmascara la distribució desigual de les confrontacions mediambientals tot reservant per al litoral i l’àrea d’Alacant les que es deriven de la construcció d’habitatges i xarxa viària, i les ocasionades per l’extracció minera i el dipòsit de residus a l’interior de Castelló i València.
Effect of soybean expeller supplementation during the final phase of sow gestation on litter birth weight
Authors: Masi Mignaco Santiago , Alba-Casals Ana , Carranza Alicia , Parada Julián
Published: July 2020

Aim: Nutrition plays a key role in the production of pigs, especially in pregnant sows, where modifications in nutritional requirements can affect their productive performance. The aim of this study was to evaluate nutritional supplementation with soybean expeller in sows during the last third of the gestation period and its effect on litter birth weight.

Materials and Methods: A quasi-experimental study was conducted on a farrow-to-finish farm, where 192 sows were equally assigned to treatment and control groups. Several variables were recorded at both the sow and piglet level. The treatment group consisted of piglets from 95 sows supplemented with soybean expeller during the final phase of gestation (20 days), and the comparison group consisted of piglets from 97 sows fed only with a commercial balanced ration (control group).

Results: Soybean expeller supplementation increased individual piglet weight by 190-270 g, and the increased number of live piglets could decrease the weight of each piglet. Moreover, the number of piglets weighing <900 g decreased by 10% as compared to the control group, indicating that supplementation could improve pre-weaning mortality.

Conclusion: Our results suggest that soybean expeller supplementation in sows during the last third of the gestation period could improve production performance, especially on organic farms.
Novel Diastereoselective Synthesis of 1-Trimethylgermyl-1-alkenes by
Hydrolysis of α-Trimethylgermylzirconacyclopentenes
Authors: Bhat Narayan G. , Villarreal Maria
Published: July 2020

1-Trimethyl-1-germylalkynes were synthesized by deprotonation of terminal alkynes with n-butyl
lithium at low temperature followed by treatment with trimethylgermyl chloride under nitrogen
atmosphere. The reagent system Cp2ZrCl2/2EtMgBr converts 1-trimethylgermyl-1-alkynes into α-
trimethylgermylzirconacyclopentenes at -78 ºC for 1 h followed by stirring at room temperature
overnight. These novel intermediates are hydrolyzed at 0 ºC for an hour to provide the corresponding
(Z)-1-trimethylgermyl-1-alkenes in good yields (74-85%) and in high stereochemical purities (> 98%)
as evidenced by 13C spectral data.
Synthesis and Antimicrobial Activity of Novel Oxothiazolidine Derivatives
Authors: Pagar Balasaheb P.
Published: July 2020

In this article, acid hydrazide 2, a functional group, was synthesized by the reaction of (4-chloro-12-
methyl-16,17-dihydro-15-thia-6,11-diaza-cyclopenta[a]phenanthren-7-ylsulfanyl)acetic acid ethyl ester
(1) with hydrazine yield (4-chloro-12-methyl-16,17-dihydro-15-thia-6,11-diazacyclopenta[a]-
phenanthren-7-ylsulfanyl)acetic acid hydrazide (2) is discussed. The reactive acid hydrazide compound
2 was utilized for the synthesis of amides 3, Schiff’s bases 4 and thiazolidine 5 derivatives. The
structures of target compounds were confirmed by elemental analysis and spectral data. The antimicrobial
activity of new compounds were studied against Streptococcus sp., Bacillus megaterium, Staphylococcus
aureus, Escherichia coli, Bacillus cereus, Bacillus subtilis, Proteus valgaris and Pseudomonas aeroginosa
by the agar well diffusion method. Compounds 4b, 5a, 5b and 5c showed good antimicrobial activity
Synthesis, Docking Studies and Biological Evaluation of Novel N-(2-(3-fluorophenyl)-
quinolin-5-yl)benzamide Derivatives as Potent Anti-breast Cancer Agents
Authors: Rathod Shrimant V. , Shinde Kailas W. , Kharkar Prashant S. , Shah Chetan P. , Ingle Ajit V. , Lotlikar Onkar A. , Dandekar Shweta N.
Published: July 2020

A novel series of quinoline benzamide derivatives have been synthesized and screened for their anticancer
activity against a breast cancer cell line (MDA-MB-231) by MTT assay method. All the synthesized
compounds were confirmed by spectral characterization viz. FTIR, 1H & 13C NMR and MS. All the
molecules demonstrated potency less than 35 μM and were better than standard cisplatin but not
comparable to doxorubicin. Compound 3i (IC50 = 6.86 μM) exhibited better promising anti-breast cancer
activity among various synthesized molecules and in addition, docking of compound 3i into kinesin
spindle protein (KSP) active site was performed in order to predict the affinity and the orientation at
the enzyme active site.
Synthesis and in vitro Evaluation of Dihydrobenzimidazole Thiopyranooxazinone
Derivatives as a Potent Biological Agents
Authors: Kardile Deepak P. , Shirsat Mrunal K.
Published: July 2020

In the present study, dihydrobenzimidazole thiopyranooxazinone derivatives were efficiently
synthesized, which were further characterized and authenticated by means of TLC and different spectral
analysis such as IR and 1H NMR. The synthesized compounds DPK2d2 to DPK2d8 were screened for
their in vitro antimicrobial, antitubercular and anticancer activities. The results showed that the titled
compounds DPK3d1, DPK3d2 and DPK3d4 exhibited potent antimicrobial activity, shows a broadspectrum
activity against Bacillus subtilis, Escherichia coli (antibacterial) and Aspergillus niger
(antifungal) as compared to ciprofloxacin and fluconazole, respectively. Compounds DPK3d1, DPK3d3
and DPK3d5 exhibited potent antitubercular activities against Mycobacterium tuberculosis as compared
to pyrazinamide, ciprofloxacin and streptomycin. Compounds DPK3d3, DPK3d4 and DPK3d5 showed
highly potent cytotoxic activity against human lung cancer cell line (A549) as compared to adriamycin.
In silico molecular docking studies shown that all the ligands highest binding affinity range -6.7 to -8.7
for selected 1CB4 PDB of superoxide dismutase, which recognized that ligands having antioxidant
activity.
Synthesis, Spectroscopic Studies and Antispermatogenic Activity of Tri- and Pentavalent Organoantimony Derivatives of Schiff Bases
Authors: Gupta R. , Mathur A.
Published: July 2020

Diphenyl antimony(III) and triphenylantimony(V) derivatives of Schiff bases having general formulae Ph2Sb[OC(R)CHC(R′)NC6H5] and Ph3Sb[OC(R)CHC(R′)NC6H5]2 (where R=R′=CH3,C6H5; R = CH3, R′=C6H5), respectively have been prepared. Trivalent organoantimony derivatives have been synthesized by the reaction of RC(O)CHC(R′)-NH(C6H5) with Ph3Sb in 1: 1 molar ratio whereas, pentavalent organoantimony derivatives have been synthesized by the reaction of Ph3SbBr2 with Na[OC(R)CHC(R′)N(C6H5)] in 1:2 molar ratio, respectively in benzene solution. The structures of these complexes have been assigned on the basis of chemical analysis, molecular weight measurements and spectral (IR 1H & 13C NMR) studies. Schiff base (R = CH3, R′ = C6H5 ) and its corresponding organoantimony(III) and antimony(V) compounds were used for evaluation of reproductive physiological activity in male rats and for studying antifertility activity. Compounds were administrated orally for 30 days to male albino rats and after termination of treatment, animal tissue and serum were taken for histopathological, biochemical and hematological parameters
Synthesis and Biological Evaluation of 3,4-Dihydro-2H-benzo[b][1,4]-oxazine-2-carboxylic
Acid Derivatives as Antitubercular Agents
Authors: Tambe Macchindra S. , Gadhe Sonali , Choudhari Amit , Sarkar Dhiman , Sangshetti Jaiprakash N. , Patil Rajesh B.
Published: July 2020

A series of side chain modified structurally diverse 3,4-dihydro-2H-benzo[b][1,4]-oxazine-2-carboxylic
acid derivatives were synthesized and characterized by IR, 1H NMR, 13C NMR and mass spectral
study. All the newly synthesized compounds were examined for their in vitro antitubercular activity
against Mycobacterium tuberculosis H37Ra. The synthesized compounds exhibited minimum inhibitory
concentration (IC50) ranging from 5.98 to >30 (μg/mL) against MtbH37Ra. Among the screened
compounds, compounds 5a, 5c, 5d, 5f, 5g, 5h, 5I, 5j exhibited IC50 as 10.42, 11.81, 18.79, 5.98,
19.21, 24.81 and 14.81 μg/mL, respectively. The antibacterial screening study of these compounds
was conducted against four different bacteria to asses there selectivity towards MTB. The antibacterial
screening of all the synthesized compounds was conducted against four bacterial strains (Gram-negative
strains: E.coli and S.aureus; Gram-positive strains: P. aeruginosa and B.subtilis. The compounds 5a,
5b, 5c, 5e and 5j showed higher antibacterial activity up to 7-25 μg/mL. Furthermore, molecular
docking studies revealed the binding modes of the compounds in the binding site of the good agreement
with the in vitro antitubercular screening. The compounds 5a, 5c and 5f with free energy of binding
lower than -9.0 Kcal/mol binds more favourably at the binding site of panC as compared to other
compounds. Specifically, the compound 5f with free energy of binding -9.6 Kcal/mol is indeed found
more active in docking study as well as in the in vitro antitubercular screening. These findings open
the possibility for potential lead for antituberculosis chemotherapy.
An Efficient Straightforward Synthesis of Antidepressant Drug Moclobemide
Authors: Potdar Santoshkumar M. , Waghmode Krishnakant T.
Published: July 2020

Efferent, new and simple synthesis for antidepressant drug moclobemide has been developed via two liner steps. Initially, morpholine treated with 60% aqueous solution of 2-bromoethylamine hydrochloride under solvent and catalyst free condition leads to a key intermediate N-(2-aminoethyl)morpholine, which subsequently treated with p-chlorobenzoic acid in presence of commercially available solid catalysts, afforded moclobemide with good yield. Mild reaction conditions, short reaction time, easy workup, cost-effective, environment friendliness and high yields are attractive advantages of the present method, so our synthetic strategy was applicable to large scale manufacturing of moclobemide every conveniently.
Study of the pterigidal canal (vidian canal) through images of cone beam computer tomography.
Authors: Santana Fernanda Fritoli Marcondes , Silveira Marcos Paulo Motta , Diamantino Pedro Jacy Santos , Fardim Karolina Aparecida Castilho , Manhães Júnior Luiz Roberto Coutinho , Costa André Luiz Ferreira , Saavedra Guilherme de Siqueira Ferreira Anzaloni , Lopes Sérgio Lucio Pereira de Castro
Published: July 2020

Objective: The aim of this study was to evaluate the pterygoid canal (PC) by Cone Beam Computed Tomography (CBCT), establishing its configuration and proximity with anatomical structures. Material and Methods: We evaluated 398 CBCT exams, all from a public University radiology clinic archive. Four parameters were evaluated: single or double PC, distance between PC and the inferior part of the sphenoid sinus (SS), ratio of PC and SS and the distance between the PC and the foramen rotundum. Results: It was observed that most of the PC of the sample presented simple morphology, the most frequent type of relationship between the PC and the SS on both sides was the close contact with the wall. Among the cases that there were some distances between the PC and the inferior wall of the SS, the mean of this distance did not exceed 3.20 mm, being the left side (3.03 mm) slightly closer than the right (3.20 mm). Finally, the distances between the PC and the corresponding Foramen Rotundum are presented with mean values of 5.87 mm for the right side and 6.31 mm for the left side. Conclusion: CBCT examination is of paramount importance for PC identification; once in the studied sample, the mean values found evidence the close relation between the PC and the SS.KeywordsCone beam computed tomography; Endonasal approach; Vidian canal.
Assessment of remineralization potential of Theobromine and Sodium Fluoride gels on Artificial Caries like lesions
Authors: Elsherbini Mohamed Saber
Published: July 2020

Objective: To compare the remineralization potential of theobromine and sodium fluoride gels on artificial caries like lesion. Materials and Methods: Forty longitudinal halves of human mandibular premolars were equally divided into 4 groups of 10 samples each: control group (C), samples were stored in distilled water during the experiment period. The remaining 30 specimens were subjected to demineralization protocol to create caries like lesions. samples were immersed for three days in a demineralization solution (pH 5.0) containing 0.2% carbopol and 0.1% lactic acid saturated with calcium phosphate tribasic. The samples were subdivided into 3 equal groups according to the treatment applied during the pH cycle. Demineralization group “D”: no treatment applied. Group “F” treated with 2000 mg/liter sodium fluoride gel. Group “T” treated with 200 mg/liter theobromine gel. The specimens of the two studies groups were subjected to Demineralization- Remineralization PH Cycle Protocol for 5 days (Alternating four steps: 1: Treatment material, fluoride or theobromine ˜= 3 minutes. 2: Demineralizing solution 3 hours. 3: treatment material ˜= 3 minutes. 4: Remineralizing solution till the next cycle). The samples were investigated by scanning electron microscope (SEM) and energy dispersive x-ray analysis (EDXA). Results: The enamel of the demineralization group was porous with artificial caries like changes exposing the subsurface enamel rods with severe rod core defects. Theobromine gel and fluoride gel groups showed marked improvement in the surface characteristics in the enamel in both groups. Theobromine gel group showed more observable enamel surface improvement than the fluoride gel group. EDXA revealed that the calcium-phosphorus ratio displayed a descending order: (C > T > F > D). The differences between the two tested groups were not statistically significant. Conclusion: Theobromine gel had more effective remineralizing potential than fluoride gel as a result of its effect in improving the enamel surface characteristics of human teeth.KeywordsDental caries; Dental enamel, Ultrastructure; Hardness; Microscopy; Electron; Scanning; Sodium Fluoride, Therapeutic use; Theobromine/therapeutic use.
Failure of miniscrews installed in maxilla and mandible: a systematic review and meta-analysis
Authors: Batista dos Santos Sandro Henrique , Poletto-Neto Victório , Lima de Queiroz Ana Beatriz , Sarkis-Onofre Rafael , Pereira-Cenci Tatiana
Published: July 2020

Objective: The aim of this systematic review was to compare the clinical failure rate of orthodontic miniscrews in maxilla and mandible. Material and Methods: Randomized controlled trials of patients in orthodontic treatment, which required miniscrews for orthodontic intervention reporting the failure rate of miniscrews in the maxilla and mandible were searched in Pubmed database. Two authors independently reviewed all identified titles and abstracts for eligibility. Comparison between failures in maxilla and mandible were estimated using pairwise meta-analysis to calculate the relative risk (RR) of failure and the 95% confidence intervals using a random-effect model. The reports of randomized trials were assessed for bias using the Cochrane risk of bias tool. Results: Four studies fulfilled the eligibility criteria. 299 patients with a total of 628 miniscrews installed were included in the analysis. The analysis showed a 0.55 RR (95% CI 0.23–1.29) and I2 = 85%. All studies had an unclear risk of bias regarding to the two following items: allocation concealment, blinding of participants and personnel. All studies had a low risk of bias with regard to incomplete outcome data and selective reporting. The results did not demonstrate statistical difference between risk of failure of miniscrew between maxilla and mandible. Conclusion: The results of the meta-analysis showed that miniscrews installed in maxilla presents reduced risk of failure. A tendency of higher number of failures in mandible was also demonstrated. However, results should be interpreted with caution because of the very low quality of included studies and the differences among methodologies. KeywordsMeta-analysis; Orthodontic anchorage procedures; Review.
Study of Organic Pollutants in the Muscles of fish Collected from El-Mahmodia Stream at El-Beheira Governorate, Egypt
Authors: Radwan E H , Mokhamer EL-Hassan M , Radwan K H , Elsaka M
Published: July 2020

The purpose of this study is to evaluate the impact of organic pollution of EL-Mahmodia canal on the fish (Oreochromis niloticus)muscles tissues collected from two sites at EL-Mahmodia canal in summer and winter 2017. EL-Mahmodia canal is exposed to excessive of effluents which impact fish. The present results showed high concentrations of organic pollutants, particularly in winter. Organic pollutants were analyzed using the gas-chromatography-mass spectrometry (GC-MS). A variety of environmental screening studies concerning varieties of water pollutants in Egypt, the target of the present study was to scan the organic pollutants of El-Mahmodia stream at El-Beheira Governorate, Egypt within the muscles of Tilapia fish. Within the present study, it was found that; the analysis of fish muscles in summer season showed a high level of organic pollutants. The organic pollutants that are reported in the muscle of fish in the polluted site were reported as; Dimethomorph-(E), Hexestrol, Diisobutyl phthalate, Diamyl phthalate, Di-n-propyl phthalate, Chlorpyrifos, Phorate sulfoxide, Exaltolide (15-Pentadecanolide), Chlorfenapyr, Pyridate, Ethofumesate, Bis (2-ethylhexyl)phthalate, Dicyclohexyl phthalate, Di-n-octyl phthalate, Tricresylphosphate, meta-, XMC (3, 4-Dimethylphenyl N-methyl, XMC (3,5-Dimethylphenyl N-methyl, Hexestrol, Thymol, Kinoprene, Diisobutyl phthalate, Diisobutyl phthalate, Di-n-hexyl phthalate, Di-n-hexyl phthalate, Carbofuran-3-keto, Tefluthrin, cis-, Carbofuran-7-phenol, Carbofuran, Dicyclohexyl phthalate, Di-n-propyl phthalate, Di-n-propyl phthalate, Bis(2-ethylhexyl)phthalate, Ethofumesate, Hexestrol, Kinoprene, Di-n-hexyl phthalate, Exaltolide (15-Pentadecanolide), Spiroxamine metabolite (4-tert-b), Chlorfenapyr, Tricresylphosphate, para, Tricresylphosphate, meta-, Tricresylphosphate, ortho-, XMC (3, 5-Dimethylphenyl N-methyl, XMC (3,4-Dimethylphenyl N-methyl, Fluroxypyr-1-methylheptyl ester, Cashmeran, Propargite metabolite (Cyclohexa), and Quinoclamine. The present results showed that Diisobutyl phthalate, Bis(2-ethylhexyl)phthalate, Pyridate and Ethofumesate were detected in winter season in the polluted site, whereas, Bis (2-ethylhexyl) phthalate, and Pyridate were the only organic pollutants that were found in winter in the reference site. The accumulation patterns of organic pollutants percentage in the polluted site in summer in the muscles of O. niloticus were in the following order: Chlorpyrifos> Diamyl phthalate> Diisobutylphthalate> Di-n-butylphthalate> Diamyl phthalate> Bis (2-ethylhexyl) phthalate, whereas, in the reference site in summer, it was Chlorpyrifos> Chlorfenapyr> Di-n-butylphthalate> Diisobutylphthalate> Hexestrol> Di-nhexyl phthalate. The accumulation patterns of organic pollutants in the polluted site in winter in the muscles of O. niloticus, were in the following order: Bis(2-ethylhexyl)phthalate> Pyridate> Ethofumesate, whereas in the reference site it was; Bis (2-ethylhexyl)phthalate> Pyridate.
Recent New Results and Achievements of California South University (CSU) BioSpectroscopy Core Research Laboratory for COVID-19 or 2019-nCoV Treatment: Diagnosis and Treatment Methodologies of “Coronavirus”
Authors: Heidari Alireza , Caissutti Angela , Henderson Maria , Schmitt Katrina , Besana Elizabeth , Esposito Jennifer , Peterson Victoria
Published: July 2020

Coronavirus nanoparticles show a strong peak of Plasmon absorption in ultraviolet–visible zone. A strong interaction exists between the surface of Coronavirus nanoparticles and Bcr–Abl tyrosine–kinase inhibitors (TKI) such as Imatinib (STI571), Nilotinib (AMN107), Dasatinib (BMS–345825), Bosutinib (SKI–606), Ponatinib (AP–24534) and Bafetinib (INNO–406). Bcr–Abl tyrosine–kinase inhibitors (TKI) such as Imatinib (STI571), Nilotinib (AMN107), Dasatinib (BMS–345825), Bosutinib (SKI–606), Ponatinib (AP–24534) and Bafetinib (INNO–406) cause to aggregation of Coronavirus nanoparticles linked to DNA/RNA and hence, lead to widening of peak Plasmon of Coronavirus nanoparticles surface at 550 (nm) and emerging a new peak at higher wavelength. In the current project, this optical characteristic of Coronavirus nanoparticles is used to time investigate of interaction between different Bcr–Abl tyrosine–kinase inhibitors (TKI) such as Imatinib (STI571), Nilotinib (AMN107), Dasatinib (BMS–345825), Bosutinib (SKI–606), Ponatinib (AP–24534) and Bafetinib (INNO–406) and Coronavirus nanoparticles. The results were shown that Bcr–Abl tyrosine–kinase inhibitors (TKI) such as Imatinib (STI571), Nilotinib (AMN107), Dasatinib (BMS–345825), Bosutinib (SKI–606), Ponatinib (AP–24534) and Bafetinib (INNO–406) with shorter chain length interact faster with Coronavirus nanoparticles. Therefore, a simple and fast method for identification of Bcr–Abl tyrosine–kinase inhibitors (TKI) such as Imatinib (STI571), Nilotinib (AMN107), Dasatinib (BMS–345825), Bosutinib (SKI–606), Ponatinib (AP–24534) and Bafetinib (INNO–406) with various chain length using red shift in surficial Plasmon absorption is presented.
Quantitative Computational Prediction of the Consensus B-cell Epitopes of 2019-nCoV
Authors: Isea Raúl
Published: July 2020

The goal of this paper is to obtain the numerical consensus of B cell epitopes from the three-dimensional structure of the prefusion spike glycoprotein of the new betacoronavirus that could lead to the development of a vaccine to 2019-nCoV. In order to do that, we first calculated the B-cell epitopes that are predicted using fourteen different mathematical algorithms. Later, we obtained the consensus of B-cell epitopes according to the Similarity Index, and finally selecting the best candidates according to the results of a function called  which is evaluated for the glycoprotein. The best candidates that we obtained in order to design a vaccine are SSANNCT, PLQSYGFQPT, TESNKKFLP, NNSYEC, AENS, LPDPSK and YDPLQPE.
Project-Based Learning Integrated To Stem (Stem-Pjbl) To Enhance Arabic Learning Hots-Based
Authors: Harun Uhame Binti
Published: July 2020

HOTS are the skills needed at this time. STEM-PjBL model is one learning model that can be applied to improve students' higher-order thinking skills. STEM-PjBL is learning that integrates four fields, namely science, technology, engineering, and mathematics, which are project-based learning. Therefore, this learning model encourages students to be active, creative, and innovative in learning, which is in line with the educational goals in Learning Arabic as a foreign language. The research method in this article descriptively is library research. Data obtained from the results of literature studies in the form of books and articles relating to STEM-PjBL using the technique of documentation or searching of library sources for data collection. Data analysis techniques using data triangulation. This study shows that the STEM-PjBL learning model is a learning model that can improve students' higher-order thinking skills (HOTS). Also, learning Arabic can use the STEM-PjBL learning model.
Subsistence and persistence: agriculture in the Central Plains of China through the Neolithic to Bronze Age transition
Authors: Jing Yuan , Campbell Roderick , Castellano Lorenzo , Xianglong Chen
Published: July 2020

The Neolithic to Bronze Age transition (c. 5000–3500 BP) saw dramatic socio-economic developments in ancient China. Complex polities emerged in many regions, only to decline and collapse by the end of the period. In the Central Plains area, however, these centuries laid the foundations for China's first dynasties. This article presents zooarchaeological, palaeobotanical and isotopic research from key sites of the Central Plains spanning the period c. 5000–3500 BP. The results demonstrate that, contrary to narratives of the climate-induced collapse of these polities, Central Plains agricultural regimes intensified and diversified during the Neolithic to Bronze Age transition.
Mortuary practices of the first Polynesians: formative ethnogenesis in the Kingdom of Tonga
Authors: Valentin Frederique , Clark Geoffrey , Parton Philip , Reepmeyer Christian
Published: July 2020

Ancestral Polynesian Society has been argued to represent a formative stage in Polynesian ethnogenesis. Recently discovered human burials at the Talasiu midden site in Tonga, dating to c. 2650 cal BP, now provide the earliest known evidence for Ancestral Polynesian mortuary behaviour. This article presents and evaluates the burials, comparing archaeological evidence for Talasiu mortuary practices with those of older Lapita and more recent Tongan burials, as well as with Ancestral Polynesian Society funerary activities inferred through linguistic reconstruction. These comparisons emphasise that several socio-cultural behaviours that are important to contemporary Polynesian societies were expressed very differently in the past.
Meropi Tzanetakis / Heino Stöver (Hrsg.) (2019): Drogen, Darknet und organisierte Kriminalität. Herausforderungen für Politik, Justiz und Drogenhilfe
Authors: Marx Stefan Alexander
Published: July 2020

n/a
Intratumor heterogeneity of prognostic DNA-based molecular markers in adrenocortical carcinoma
Authors: Jouinot Anne , Lippert Juliane , Fassnacht Martin , de La Villeon Bruno , Septier Amandine , Neou Mario , Perlemoine Karine , Appenzeller Silke , Sibony Mathilde , Gaujoux Sébastien , Dousset Bertrand , Libe Rossella , Groussin Lionel , Ronchi Cristina L , Assié Guillaume , Bertherat Jérôme
Published: July 2020

Background:

The prognosis of adrenocortical carcinoma (ACC) is heterogeneous. Genomic studies have identified ACC subgroups characterized by specific molecular alterations, including features measured at DNA level (somatic mutations, chromosome alterations, DNA methylation), which are closely associated with outcome. The aim of this study was to evaluate intratumor heterogeneity of prognostic molecular markers at the DNA level.

Methods:

Two different tissue samples (primary tumor, local recurrence or metastasis) were analyzed in 26 patients who underwent surgery for primary or recurrent ACC. DNA-related biomarkers with prognostic role were investigated in frozen and paraffin-embedded samples. Somatic mutations of p53/Rb and Wnt/β-catenin pathways were assessed using next-generation sequencing (n = 26), chromosome alteration profiles were determined using SNP arrays (n = 14) and methylation profiles were determined using four-gene bisulfite pyrosequencing (n = 12).

Results:

Somatic mutations for ZNRF3, TP53, CTNN1B and CDKN2A were found in 7, 6, 6 and 4 patients, respectively, with intratumor heterogeneity in 8/26 patients (31%). Chromosome alteration profiles were ‘Noisy’ (numerous and anarchic alterations) in 8/14 and ‘Chromosomal’ (extended patterns of loss of heterozygosity) in 5/14 of the study samples. For these profiles, no intratumor heterogeneity was observed. Methylation profiles were hypermethylated in 5/12 and non-hypermethylated in 7/12 of the study samples. Intratumor heterogeneity of methylation profiles was observed in 2/12 patients (17%).

Conclusions:

Intratumor heterogeneity impacts DNA-related molecular markers. While somatic mutation can differ, prognostic DNA methylation and chromosome alteration profile seem rather stable and might be more robust for the prognostic assessment.
El encuentro en el juego: formulaciones sobre la reserva lúdica
Authors: Fajn Sergio
Published: July 2020

En este texto se aborda el concepto de reserva lúdica, enmarcado en el territorio de la Psicogerontología, ligándola con los contenidos de la teoría de la identidad flexible;   con elaboraciones articuladas del campo del juego provenientes del psicoanálisis y de las ciencias sociales.
Juego, desmadre y organización social: el caso de una barra de fútbol en México
Authors: Duarte Bajaña Ricardo
Published: July 2020

Explicar las relaciones entre “desmadre”, juego y organización social en una agrupación de aficionados al fútbol, en contraste con la distancia que convencionalmente se ha señalado que tienen estas categorías. A partir del diseño etnográfico, se estudió a la Banda del Rojo, una barra de futbol de la ciudad de Toluca, en el Estado de México; se evidencia el desmadre-juego dentro de la agrupación en el marco de una organización social que los integrantes han construido una manera diferente a la impuesta en el hogar, la escuela y en su contexto sociocultural. En este caso, el orden y el desorden dejan de ser polos opuestos y en su lugar formulan una manera de relacionarse que combina juego y jerarquía, turbulencia y organización social.
Recreación, juego y decolonialidad: una aproximación urgente y necesaria
Authors: Sánchez Londoño Néstor Daniel
Published: July 2020

El documento presenta definiciones sobre conceptos que se emplean como sinónimos e intenta demarcar una línea necesaria entre éstos; posteriormente trata de hacer una mirada crítica sobre el juego, desplazado por los españoles, que tuvo que ser proscrito para imponer nuevas formas de jugar de manera que éstas sirvieran más a los intereses de la cosmogonía que se implantaba; el documento intenta identificar también como las formas jugadas que nos impone el mundo globalizado, también desplaza y menosprecia acciones de juego que se reconocen como tradicionales y como las nuevas propuestas resquebrajan aspectos que en el juego se favorecían como el desarrollo de la autonomía para construir referentes de libertad. Finalmente el documento propone una mirada crítica al juego, a la recreación y a las formas de entretenimiento que se imponen, proponiendo que la diversión en la cotidianidad, pueda favorecer un proceso recreativo que nos construya como pueblo.
Bird’s-Eye Views of Alberta’s Land Boom of the 1910s
Authors: Stevens Rhys
Published: July 2020

Bird's-Eye Views of Alberta's cities and towns, including a 25-view appendix.
Universidad y Filosofía de la Praxis Artística: teatro, pensamiento teatral, Ciencias del Teatro
Authors: Dubatti Jorge
Published: July 2020

Asistimos a nuevos desafíos para la investigación artística fuera y dentro de la Universidad. Se ha puesto en primer plano la necesidad de practicar y pensar desde nuevas aproximaciones las relaciones entre arte y conocimiento, y especialmente los vínculos entre la praxis artística y la ciencia en el marco universitario. Este trabajo propone articular las nociones de teatro, pensamiento teatral y Ciencias del Teatro como diferentes formas de producir conocimiento desde el acontecimiento teatral, es decir, Filosofía de la Praxis Teatral. Se promueve la identificación de cuatro figuras fundamentales en la producción de conocimiento desde/para/sobre la praxis artística: el artista-investigador, el investigador-artista, el artista asociado a un investigador no-artista especializado en arte y el investigador que (sin ser artista) produce conocimiento participando en el acontecimiento artístico (ya sea por su estrecha relación y familiaridad con el campo artístico o por su trabajo en el convivio como espectador; es el investigador que ubica su laboratorio en el acontecimiento teatral, no solo en el gabinete científico), con sus respectivas combinaciones. Se propone además distinguir un pensamiento teatral sustentado o no sustentado por las prácticas artísticas. Finalmente, pensar el teatrista como intelectual específico, en paradójica complementariedad con la crisis del teatrista “ilustrado”.