bluuebunny/crossref_metadata_2025 huggingface dataset:
Motivational spheres of student youth in modern Russian society
Authors: Kolesnikova Galina I. , Barkova Eleonora Vl. , Oparina Nina A. , Vlasova Victoria N. , Potapkina Ekaterina V. , Panov Maksim O.
Published: February 2023

The article analyzes the elements that make up the motivational field of student youth and determine its specificity in the context of the modern realities of Russian society. The subject of the research is the content filling of such elements of the motivational field in the basic directions of activity in the youth environment as the choice of a profession, the motives of interpersonal communication, the structure of extracurricular interests, and the motives for choosing a hobby, a spouse. The theoretical foundation of the research is the works of domestic and foreign authors of the socio-philosophical and sociological directions. Based on the goal and objectives, the work uses comparative analysis, interdisciplinary synthesis and other techniques of general scientific methodology. Based on the results obtained, it can be concluded that most higher education students have the ratio of biological and psychological age within the age norm.
The influence of counselling on academic performance of undergraduate students
Authors: Oluwaferanmi Oyelami Blessing , Uzun Gizem Öneri
Published: February 2023

For undergraduate students, education plays an important role in their development of skills such as cognitive skills and abilities. The aim of this study was to examine the influence of the counseling experiences of undergraduates on their academic performance. The t-test and ANOVA statistics were used to test the hypotheses at a 0.05 alpha level of significance. The data collected with the help of the research questionnaire was analyzed with the help of the Statistical Package. This study will make use of data collection in the form of questionnaire administration to determine how counseling has influenced the students’ academic performance. The result of the study showed that 181 participants out of the 262 said that they had experienced counseling before, 159 of them mentioned that their academic performance improved after counseling. The outcome of the study also showed that most of the participants only go for counseling yearly.
Shaping the dynamics of aharonov-bohm caged localized modes by nonlinearity
Authors: Stojanovic Miljana , Mancic Ana , Stepic Milutin , Maluckov Aleksandra
Published: February 2023

Two-dimensional dice lattice can be dressed by artificial flux to host the
Aharonov-Bohm (AB) caging effect resulting in the occurrence of a fully
flatband spectrum. Here, we focus on the dynamics of flatband compact
localized eigenmodes shared by a few unit cells in two snowflake
configurations. We numerically show the possibility of dynamically stable
propagation of two types of compact localized complexes by tuning the
nonlinearity. The caging is imprinted in complexes dynamics regardless of
the type and strength of nonlinearity. On the other hand, nonlinearity can
only affect the appearance of the caged complex. These findings open a new
route for the manipulation of structured light in photonic systems.
Evaluation of a Produce Prescription Program for Patients With Diabetes: A Longitudinal Analysis of Glycemic Control
Authors: Hager Kurt , Shi Peilin , Li Zhongyu , Chui Kenneth , Berkowitz Seth A. , Mozaffarian Dariush , Chhabra Jyoti , Wilken Joel , Vergara Cunegundo , Becker Erica , Small Sara , Ling Brent , Cash Sean B. , Folta Sara C. , Zhang Fang Fang
Published: February 2023

OBJECTIVE

Produce prescriptions have shown promise in improving diabetes care, although most studies have used small samples or lacked controls. Our objective was to evaluate the impacts of a produce prescription program on glycemic control for patients with diabetes.

RESEARCH DESIGN AND METHODS

Participants included a nonrandom enrollment of 252 patients with diabetes who received a produce prescription and 534 similar control participants from two clinics in Hartford, Connecticut. The start of the COVID-19 pandemic in March 2020 coincided with program implementation. Produce prescription enrollees received vouchers ($60 per month) for 6 months to purchase produce at grocery retail. Controls received usual care. The primary outcome was change in glycated hemoglobin (HbA1c) between treatment and control at 6 months. Secondary outcomes included 6-month changes in systolic (SBP) and diastolic blood pressure (DBP), BMI, hospitalizations, and emergency department admissions. Longitudinal generalized estimating equation models, weighted with propensity score overlap weights, assessed changes in outcomes over time.

RESULTS

At 6 months, there was no significant difference in change in HbA1c between treatment and control groups, with a difference of 0.13 percentage points (95% CI −0.05, 0.32). No significant difference was observed for change in SBP (3.85 mmHg; −0.12, 7.82), DBP (−0.82 mmHg; −2.42, 0.79), or BMI (−0.22 kg/m2; −1.83, 1.38). Incidence rate ratios for hospitalizations and emergency department visits were 0.54 (0.14, 1.95) and 0.53 (0.06, 4.72), respectively.

CONCLUSIONS

A 6-month produce prescription program for patients with diabetes, implemented during the onset of the COVID-19 pandemic, was not associated with improved glycemic control.
Combination of Multiple Low-Risk Lifestyle Behaviors and Incident Type 2 Diabetes: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies
Authors: Khan Tauseef A , Field David , Chen Victoria , Ahmad Suleman , Mejia Sonia Blanco , Kahleová Hana , Rahelić Dario , Salas-Salvadó Jordi , Leiter Lawrence A
Published: February 2023

  

Objective: Combined low-risk lifestyle behaviors (LRLBs) have been associated with reduction in type 2 diabetes risk. This relationship has not been systematically quantified. 

Research design and methods: A systematic review and meta-analysis was conducted to assess the association of combined low-risk lifestyle behaviors with type 2 diabetes. Databases was searched up to September 2022. Prospective cohort studies reporting the association between a minimum of 3 combined LRLBs (including healthy diet) with incident type 2 diabetes were included. Independent reviewers extracted data and assessed study quality. Risk estimates of extreme comparisons were pooled using random-effects model. Global dose-response meta-analysis (DRM) for maximum adherence was estimated using one-stage linear mixed model. The certainty of the evidence was assessed using GRADE. 

Results: 30 cohort comparisons (n=1,693,753) involving 75,669 incident type 2 diabetes cases were eligible. LRLBs, with author defined ranges, were healthy body weight, healthy diet, regular exercise, smoking abstinence or cessation, and light alcohol consumption. LRLBs were associated with 80% lower risk of type 2 diabetes (relative risk (RR), 0.20 [95% confidence interval, 0.17 to 0.23]), comparing the highest with lowest adherence. Global DRM for maximum adherence to all 5 LRLBs reached 85% protection (RR, 0.15 [95% CI, 0.12 to 0.18]. The overall certainty of the evidence was graded as high.

Conclusions: There was a very good indication that combination of LRLBs that include maintaining a healthy bodyweight, healthy diet, regular exercise, smoking abstinence or cessation and light alcohol consumption was associated with a lower risk of incident type 2 diabetes.  

Study registration: ClinicalTrials.gov (NCT03234101)
Evaluation of a Produce Prescription Program for Patients with Diabetes: A Longitudinal Analysis of Glycemic Control
Authors: Hager Kurt , Shi Peilin , Li Zhongyu , Chui Kenneth , Berkowitz Seth A. , Mozaffarian Dariush , Chhabra Jyoti , Wilken Joel , Vergara Cunegundo , Becker Erica , Small Sara , Ling Brent , Cash Sean B. , Folta Sara C. , Fang Zhang Fang
Published: February 2023

  

Objective: Produce prescriptions have shown promise to improve diabetes care, although most studies used small samples or lacked controls. Our objective was to evaluate impacts of a produce prescriptions program on glycemic control for patients with diabetes.

Research Design and Methods: Participants included a non-random enrollment of 252 patients with diabetes who received produce prescriptions and 534 similar controls from two clinics in Hartford, CT. The start of the COVID-19 pandemic in March 2020 coincided with program implementation. Produce prescription enrollees received vouchers ($60/month) for six months to purchase produce at grocery retail. Controls received usual care. Primary outcome was change in glycated hemoglobin (HbA1c) between treatment and controls at six months. Secondary outcomes included 6-month change in systolic and diastolic blood pressure (SBP and DBP), body mass index (BMI), hospitalizations, and emergency department admissions. Longitudinal generalized estimating equation models, weighted with propensity score overlap weights, assessed changes in outcomes over time. 

Results: At six months, there was no significant difference in change in HbA1c between treatment and control groups, with a difference of 0.13 percentage points (95% CI: -0.05, 0.32). No significant differences were observed for change in SBP (3.85 mmHg ( -0.12, 7.82)), DBP (-0.82 mmHg (-2.42, 0.79)), or BMI (-0.22 kg/m2 (-1.83, 1.38)). The incidence rate ratios for hospitalizations and emergency department visits were 0.54 (0.14, 1.95) and 0.53 (0.06, 4.72).

Conclusion: A 6-month produce prescription program for patients with diabetes, implemented during the onset of the COVID-19 pandemic, was not associated with improved glycemic control.
Cilia and ciliopathy
Authors: Indeykin F. A , Mavlikeev M. O , Deev R. V
Published: February 2023

Cilia (cilia) are organelles that are characteristic exclusively for eukaryotes and are found in protozoa, on somatic and germ cells of multicellular, as well as gametes of many plants. In humans, two main types of cilia are distinguished: motile and sensory; also in embryogenesis, it is customary to isolate special nodular cilia necessary for the normal course of gastrulation and possibly subsequent histo- and organogenesis. Motile cilia provide the movement of the liquid medium relative to the cell in the respiratory tract, the ventricular system of the brain and the fallopian tubes, or the movement of the cell itself in the case of sperm. The main function of sensory cilia is the perception of changes in the external environment and the signal molecules inside it and their conversion into intracellular signals that regulate proliferation, differentiation, and programmed cell death. Ciliopathies, a group of pathological conditions associated with impaired development, structure, and functioning of cilia, are of clinical interest. The most studied ciliopathies include polycystic kidney disease, nephronophysis, Barde-Beadle, Joubert, Mekel, Kartagener, Karoli etc. Clinical nephronophthisis and morphological analysis of the case of Caroli, syndrome is given.
Prognostic significance of tumour infiltrating lymphocytes in different molecular subtypes of invasive breast carcinoma
Authors: Tashireva L. A , Lyapunova L. S , Buzenkova A. V , Pankova O. V , Zavyalova M. V , Perelmuter V. M
Published: February 2023

Metastasis is the main cause of death from cancer, including breast cancer, so the search for simple and effective prognostic parameters is becoming a priority for researchers. The number of tumor-infiltrating lymphocytes is a proven prognostic factor for triple negative and Her2-positive, but not luminal, molecular subtypes of breast cancer. Possible reasons for the failure of this prognostic parameter for luminal subtypes of breast cancer may be the tumor morphological heterogeneity. Objective: to assess the prognostic significance of the tumor-infiltrating lymphocytes number in the invasive breast carcinoma of a non-specific type (IC NST) of various molecular subtypes, taking into account its morphological heterogeneity. 152 patients with IC NST (T1-3N0-2M0) aged 29 to 75 years were enrolled in the study. The molecular subtype was determined using immunohistochemical analysis of the expression of estrogen and progesterone receptors, Ki-67 and Her2/neu. TILs were assessed in accordance with the recommendations of the International TILs Working Group. It was shown that TILs near the structures of various types is heterogeneous only in patients with the luminal Her2-negative subtype of IC NST. In addition, was found that the development of hematogenous metastases and worse metastatic-free survival in this cohort of patients is associated with a high TILs near solid structures and also depended on Ki-67 level. Thus, TILs near solid structures is a potential prognostic factor for the development of distant metastasis in the luminal Her2-negative and Ki-67 level less 20% subtype of IC NST.
Poor oocyte quality as a cause of embryo fragmentation in IVF program: clinical case report
Authors: Maysina E. N , Salimov D. F , Lisovskaya T. V
Published: February 2023

High degree of embryo fragmentation correlates with absence of implantation in IVF programs. The aim of the work was to determine the most probable cause of embryo fragmentation and ineffective in vitro fertilization (IVF) program on the example of a specific clinical situation and based on the analysis of literature data. In contrast to the common form of infertility, associated with the absence of ovulation and constituting 35-40% in the structure of infertility factors, , this clinical situation is unusual due to the fact that pregnancy as a result of repeated IVF programs did not occur due to the production of fragmented embryos with a preserved ovarian reserve and the exclusion of other infertility factors. The successful solution of reproductive problems in this couple is obviously associated with the use of the oocyte donation program.
Role of autophagy in response of epithelial ovarian cancer cells to cisplatin treatment and cisplatin resistance
Authors: Mazitova A. M , Topchu Iu. A , Mingazova L. A , Biktagirova E. M , Abramova Z. I , Gabbasov R. T
Published: February 2023

Ovarian cancer survival rate is inversely associated with the extent of tumor metastasis. One of the main treatment approaches against ovarian cancer is employment of platinum based therapies, including cisplatin. Majority of ovarian cancer patients develop cisplatin resistance. We aimed to investigate roles for macroautophagy in response of epithelial ovarian cancer cells to cisplatin, including changes in cell motility, as well as in development of cisplatin resistance. Cisplatin treatment induced autophagy in Caov-3 cells in vitro, as well as resulted in increased cell motility. Pharmacologic inhibition of autophagy by wortmannin eliminated the effect of cisplatin on cell motility. We further selected Caov-3 cells with acquired cisplatin resistance and observed elevated baseline expression of autophagy markers in the resistant cells. Our data indicate a role for autophagy in development of cisplatin resistance by the EOC cells, as well as a potential role for cisplatin-induced autophagy in ovarian tumor metastasis.
A.S. Benyan, I.V. Gilevich-Rodkina, L.S. Tselkovich, R.B. Balter, E.P. Shatunova, T.V. Ivanova, A.R. Ibragimova, OA. Ilchenko, G.I. Teleeva, O.V. Tyumina, A.Yu. Ryabov Prospects for restoring the endometrium function in women with hyperplasia of the uterine mucosa after an unsuccessful attempt of extracorporeal fertilization
Authors: Benyan A. S , Gilevich-Rodkina I. V , Tselkovich L. S , Balter R. B , Shatunova E. P , Ivanova T. V , Ibragimova A. R , Ilchenko O. A , Teleeva G. I , Tyumina O. V , Ryabov A. Yu
Published: February 2023

One of the causes of infertility is endometrial hyperplasia. The treatment of it is a prerequisite before the in vitro fertilization. The aim of the study was to develop measures to prevent the development of endometrial hyperplastic processes in patients who have undergone the in vitro fertilization. The paper discusses the results of hysteroscopic, immuno-histochemical, and histological examinations of the endometrium of 179 infertile women with hyperplasia of the uterine mucosa before the ovulation stimulation in the in vitro fertilization protocols and after the protocols. The results were compared with similar indicators of 119 fertile patients with endometrial hyperplastic processes. Significant differences in the expression of endometrial receptivity were obtained. Immunohistochemical analysis indicated a significant decrease in the level of α-2 microglobulin of fertility with preserved estrogen and progesterone receptions even with a normal histological result. Based on the results of the study, an algorithm for the rehabilitation of patients after unsuccessful attempts at in vitro fertilization is proposed. It consists of three stages and allows to restore normal morphological and functional indicators of the endometrium, which is important for the subsequent implementation of the reproductive function. With a personalized approach to hormone therapy, complete restoration of endometrial function in infertile patients is achieved in 64% of cases. It was found that with an adequate reaction of the body to the therapeutic effect, endometrial reception is restored regardless of the presence or absence of fertility. As a prognostic criterion for pregnancy, it is possible to use indicators of α-2 microglobulin of fertility in the menstrual blood and ultrasound parameters of the endometrium in various phases of the menstrual cycle.
Extracellular ATP molecules effects the functional properties of granulocyte plasma membrane
Authors: Skorkina M. Yu , Shevchenko T. S , Fetter V. V , Cherkashina O. V , Palchikov M. Yu
Published: February 2023

Extracellular ATP is an auto- and paracrine regulator in the mechanisms of intercellular signaling. It is the trigger starting the purinergic signaling cascade also. The aim of this work to study the effect of extracellular ATP on the functional properties (rigidity, surface potential, adhesive properties and osmoregulatory capabilities of the membrane) of the plasma membrane and the migration activity of granulocytes in experiments in vitro. In the experiment, the granulocyte subpopulation separated from the venous blood of healthy people was used. The experiment samples were incubated with adenosine-5-triphosphate disodium salt trihydrate in concentration 10 мМ that matches of ATP concentration released from blood cells during deformation stress in the microvasculature vessels. The stiffness and surface potential of a cell, the adhesion force between erythrocyte and granulocyte was measured by using the method of atomic force microscopy, tests with hypoosmotic load were performed and the migration activity of granulocytes was studied. As a result of the experiment, a decrease in stiffness and surface potential was found by 53.2% and 32.5 % (р
The effect of cell-mediated delivery of combination VEGF165, GDNF, and NCAM1 genes on molecular and cellular reactions in the spinal cord of pigs with contusion trauma
Authors: Davleeva M. A , Bashirov F. V , Izmailov A. A , Fadeev F. O , Sokolov M. E , Markosyan V. A , Garifulin R. R , Kuznetsov M. S , Pakhalina I. A , Minyazeva I. S , Chelyshev Yu. A , Islamov R. R
Published: February 2023

Currently, the treatments for spinal cord injury are limited. Gene therapy is one of the most promising approaches aimed at overcoming negative post-traumatic consequences in the spinal cord. Numerous studies performed in rodents indicate a positive effect of the delivery of therapeutic genes to the spinal cord to stimulate neuroregeneration. However, to bring the developed protocols of gene therapy to the stage of clinical trials, it is necessary to verify the results obtained in experiments on large laboratory animals. Objective: Immunofluorescence analysis of the response of markers of cell stress and apoptosis, synaptic proteins and neuroglia in the spinal cord of female vietnamese pot-bellied pigs after intrathecal delivery of genes encoding vascular endothelial growth factor (VEGF165), glial-derived neurotrophic factor and neuronal cell adhesion molecule (NCAM1), using human umbilical cord blood mononuclear cells (UCBMC). In experimental pigs (n = 2), 4 hours after modeling a dosed contusion injury of the spinal cord at the Th8-Th9 level, 2х106 genetically modified UCBMCs overexpressing recombinant VEGF, GDNF, and NCAM molecules in 200 |jl of saline were intrathecally injected. Control animals (n = 2) were injected with 200 jl of saline into the cerebrospinal fluid. Intact pigs (n = 2) were used to obtain baseline values for immunofluorescence analysis of post-traumatic molecular and cellular responses. After 60 days, immunofluorescence analysis in the rostral and caudal parts of the spinal cord relative to the epicenter of injury revealed positive changes in experimental pigs against the background of cell-mediated delivery of the VeGf165, GDNF, and NCAM1 genes. In the anterior horns of the rostral and caudal spinal cord of animals from the therapeutic group, a higher level of fluorescence of the synaptic protein synaptophysin, a lower number of astrocytes and microglial cells were found, which may indicate functional recovery of neurons and suppression of the development of astrogliosis. In the rostral section, in the area of the corticospinal tract, gene therapy maintained the number of oligodendrocytes, which ensure myelination of regenerating axons. The results obtained suggest that genetically modified UCBMCs, overexpressing recombinant molecules VEGF and GDNF (as therapeutic molecules) and NCAM (as a molecule providing survival and targeted targeting of cell carriers), contribute to post-traumatic regeneration of the spinal cord.
Participation of adhesion molecules in changing cell interactions during metastasis development
Authors: Shevlyuk N. N , Khalikova L. V , Khalikov A. A , Bakeev M. R , Lipatov D. O , Mustafin R. N
Published: February 2023

The review summarizes current information about the role and significance of adhesion molecules in the process of tumor metastasis. For example, different tumors is shown that changes in the expression of adhesion molecules leads to disruption of the regulatory interactions in the processes of proliferation, cytodifferentiation and migration of tumor cells, enables the cascade of pathological processes leading to the colonization of other tumor cells remote from the tumor bodies. The phenomenology of tumor development and metastasis is shown. The participation of the main groups of adhesion molecules (cadherins, integrins, selectins, immunoglobulins and white blood cell homing receptors) at the stages of metastasis is considered. A violation of cadherin expression is accompanied by a decrease in the expression of integrins involved in the formation of hemidesmosomes, while a cascade of reactions develops that contributes to the development of an aggressive malignant phenotype, cells acquire an increased ability to migrate and invade, resulting in the appearance of a tumor in secondary foci. The role of immunoglobulins in the development of metastatic process has been studied in less detail than in cadherins and integrins. It was found that immunoglobulins are involved in the formation of resistance of tumor cells to proapoptotic signals. Immunoglobulins increase the expression of metalloproteinase genes involved in the degradation of the extracellular matrix, which is a factor in the initiation of metastasis. A correlation between increased selectin expression and increased metastasis is shown. An increase in the expression level of white blood cell homing receptors leads to an increase in the invasive potential of tumors. The results of the study of cell adhesion proteins serve as a fundamental basis for the development of methods of antitumor therapy. Over the past decades, a number of immunohistochemical protein detection reactions have become one of the diagnostic methods of cancer clinics. However, the role of cell adhesion molecules in ensuring the metastasis process, as well as their significance in the prognosis of the development of the tumor process and antitumor therapy, needs to be further studied.
Study of the RS2910164 polymorphic variant of MIR-146A microRNA gene in patients with primary osteoporosis
Authors: Yalaev B. I , Khusainova R. I
Published: February 2023

MiRNAs, known as the family of short non-coding RNAs, are key repressors of gene expression and play an important role in the regulation of osteogenesis, interact with signaling molecules of bone remodeling, and control the processes of differentiation of bone cells. A study of the polymorphic variant rs2910164 (n. 303C>G) of the microRNA gene (miR-146a) and an assessment of its role in the formation of the risk of osteoporetic fractures and low bone mineral density (BMD) in a sample of postmenopausal women and men over 45 years of age was conducted. The C allele was found to be associated with a low level of bone mineral density in the lumbar spine in women. There were no significant associations of the studied locus with osteoporotic fractures in General and their separate localities in men and women, with a low level of BMD in General and various localities in men.
Genetic diagnostics and treatment of young adult acute myelomonoblastic leukemia patient using double haploidentic bone marrow transplantation
Authors: Vinogradov A. V , Izotov D. V , Rezaykin A. V , Anisimova I. V , Konstantinova T. S , Kudryashova A. V , Sazonov S. V , Sergeev A. G
Published: February 2023

Treatment ofprognostically unfavorable forms ofacute leukemia isaserious problem ofhematology, since their frequency inthe group ofadult patients reaches 60%, and inelderly patients- 80-90%.Aim: toanalyze the case ofdiagnostics and treatment ofacute myelomonoblastic leukemia with anunfavorable genetic prognosis inayoung adult female using double haploidentical bone marrow transplantation.Samples ofbone marrow and peripheral blood ofpatient K., 35years old, who recived program chemotherapy and double haploidentical bone marrow transplantation inthe Sverdlovsk Regional Hematological Centre were examined.Atthe onset ofdisease was noted hyperleukocytosis, blastaemia and infiltration ofleukemic cells inthe bone marrow. Cytochemical reactions tolipids were positive in7,0% ofblasts, small-granular and large-granular glycogen was detected in24,0% ofblast cells, and diffuse- in22,0%. Immunophenotypically, 28,0% ofblast cells were characterized byexpression ofHLA-DR, CD13, CD33, CD34, CD38, CD117, MPO-cyt, 13,0%- CD33, CD11cyt, CD64, CD14. The cytogenetic study determined the karyotype 48, XX, +4, +21[2]/ 47, XX, +4[3]/ 46, XX[2]. Non-synonymous transversions с. 2447A>Тinс-KIT gene, с.215С>GinТР53, and transition с. 2644С>ТinDNMT3A were detected using direct sequencing method. Despite the detection ofoncogenic mutations, the tumor was chemosensitive topolychemotherapy (including anthracyclines with cytarabine). However, given the unfavorable genetic prognosis, itwas decided toperform abone marrow transplantation. Due tothe lack ofanHLA-matched unrelated donor, the first haploidentical transplantation was performed from the patient'seldest daughter. At+51day, transfusion ofdonor white blood cells with correction ofthe immunosuppression scheme was performed tocorrect persistent pancytopenia. At+ 71day after the first transplantation, taking into account the remaining pancytopenia, asecond haploidentic transplantation from the patient'syounger daughter was performed. The total duration ofhematological remission was 48months, including 36months after the second haploidentical bone marrow transplantation.
Layakkah Media Papan Ludo Digunakan Pada Muatan IPA Untuk Siswa Sekolah Dasar?
Authors: Ulfa Maria , Tembang Yonarlianto , Palittin Ivylentine Datu
Published: February 2023

Papan ludo merupakan inovasi media pembelajaran sebagai penguatan materi yang berisi tentang kuis dari materi yang telah dipelajari oleh siswa. Tujuan dari penelitian ini adalah untuk mengembangkan kelayakan dan keterbacaan media papan ludo pada muatan IPA siswa kelas IVB. Metode dalam penelitian ini yaitu R&D menggunakan model Thiagarajan, atau 4D yaitu define, design, development and dissemination. Namun dalam penelitian ini dibatasi hanya sampai tahap developement karena melihat waktu pada saat penelitian dimasa pandemi. Subjek penelitian ini adalah ahli materi, ahli media dan siswa kela IV SD. Teknik pengumpulan data yang digunakan yaitu angket validasi dan angket respon peseta didik serta didukung dengan dokumentasi. Instrumen yang digunakan yaitu lembar angket validasi para ahli dan lembar angket respon siswa. Hasil penelitian ini menunjukkan bahwa media papan ludo yang dikembangkan telah divalidasi oleh 3 validator dengan presentase ahli materi 82% ahli bahasa 87% dan ahli media 89%. Sedangkan hasil rata-rata angket keterbacaan media papan ludo yang dilakukan oleh siswa yaitu sebesar 100%. Dari hasil penelitian ini dapat simpulkan bahwa penggunaan media papan ludo sangat layak digunakan dengan presentase 86% dan sangat menarik digunakan sebagai media pembelajaran muatan IPA.
Museum: Media of Non-Formal Education in Intruding Character Values Strengthening the National Self
Authors: Brata Ida Bagus , Ida Bagus Rai  , Lianda Dewi Sartika  , Ida Bagus Nyoman Wartha
Published: February 2023

Museums are scientific information service providers based on data and facts presented through collections as part of a scientific study. This study aims to analyses museum as a medium of non-formal education in instilling character to strengthen national identity. The study in this paper is classified as a descriptive-exploratory type of study. This study uses a literature review approach and data study through the internet network, combined with field studies by visiting the Bali Museum as a research locus where cultural heritage is stored. Data analyses divided into three stages, namely: data reduction, data presentation, concluding/verification. The study results show that museums are perceived as non-profit institutions that prioritize social goals, such as education. Museums as a place for cultural studies while having recreation can foster thinking skills in children. The eyes are the windows to the soul that can stimulate active, creative, critical, and innovative thinking, thus giving rise to intelligence in understanding the character values ​​that lie behind a collection of cultural heritage to strengthen national identity. The Bali Museum is the pride of the Balinese people having a fundamental role in instilling character values ​​in maintaining national identity and identity.
English Teacher Identity Crisis after Fruitless Virtual Teaching Practices During Covid-19 Outbreak in Underprivileged Institution
Authors: Kadek Wiramarta , Ni Putu Dian Utami Dewi
Published: February 2023

Education institutions are under proliferating challenges to deliver successful virtual learning in an increasingly digitized and globalized environment and especially during Covid-19 outbreak. This even become harder in academically challenging circumstance. This might put their identity as a teacher in hard situation. The aim of this research is to analyses English teacher attitudes and perception after having unsuccessful teaching practices from professional identity lens. An interpretative phenomenological analysis by utilizing dialogic interview will be employed to 4 higher education English teacher in underprivileged and newly established university to capture the intended data. After that, the data regarding teacher identity will be displayed and extensively analysed to unfold some individual phenomenon while implementing virtual classroom to teach English. This study found that our participants have evidently grown professionally during the Covid-19 epidemic time frame. Several teachers have developed some strategies to actually engage students in the virtual classroom and gained more awareness of technological issues in learning. In fact, this experience was viewed as enhancing their teacher identity. This study is expected to offer a glimpse of teacher individual situation and some insight on the effort in maintaining personal teachers’ identity during virtual learning process.
Determining the geometry of the modified shape heat transfer surface in the shell-and-tube heat exchanger
Authors:   Belgorod State Technological University named after V. G. Shukhov, Nikulin N. U. , Sheremet E. O. ,   Belgorod State Technological University named after V. G. Shukhov, Alifanova A. I. ,   Belgorod State Technological University named after V. G. Shukhov, Yakovlev V. A. ,   Saint Petersburg State University of Architecture and Civil Engineering
Published: February 2023

At present, much attention is paid to an important task in industry, namely, increasing the heat transfer coefficient of heat exchangers with smooth tubes. The article considers one of the techniques to increase the heat transfer coefficient between the heating and heated coolants in a shell-and-tube heat exchanger. The authors propose using the method of increasing the degree of turbulence of the coolant flow by equipping the plate with cylindrical ribs. The results of research carried out by the method of mathematical modeling in the ANSYS Fluent program are presented. Based on the results of mathematical modeling, the optimal rib arrangement has been chosen, which makes it possible to ensure the most complete turbulent flow around the plate. Options for placing ribs with a description of the main thermal and hydraulic characteristics of coolant flows are presented.
Features of the chemical composition of barium hydrosilicates synthesized by different technologies
Authors:   Moscow State University of Civil Engineering, Grishina A. N. , Korolev E. V. ,   Saint Petersburg State University of Architecture and Civil Engineering
Published: February 2023

The article considers the procedural factor effect on the chemical composition of barium hydrosilicates used to control the structure formation of cement stone. It is established that the initial characteristics of sodium hydrosilicate solutions (liquid glass) can influence the carbonation of the deposition product. It has been revealed that during prolonged washing of the deposition products of liquid glasses (barium hydrosilicates), their chemical composition does not change. Concentrations of solutions for synthesis also have an effect on carbonation - so, the use of low-concentration salt solutions increases the content of barium carbonate in the product. It is proposed to study the chemical composition by FTIR spectroscopy method only for powders of deposition products subjected to temperature treatment at a temperature of 800 °C for 60 minutes.The results of the study can be used to control the quality of hydrosilicate additives used at producing composite mineral binders.
Mine Testing of the CoalAwakeningBeast Gas Flow Meter for the Сurrent Outburst Hazard Forecast
Authors:   NTPK Microclim, Abramson K.M. , Baysagov Ya.Zh. ,   NTPK Microclim, Bozhko D.I. ,   STC «Industrial Safety» CJSC
Published: February 2023

In the mines developing coal seams that are dangerous and threatened by the sudden outbursts, the current forecast of outburst hazard of coal seams is carried out. It is based on the estimate of initial outgassing from freshly drilled control holes. At present, gas flow measurement is conducted using mechanical pressure meters PG2-MA and IG-1. Assessment from the readings is approximate. This leads to false results. An erroneous «not dangerous» prediction can lead to obtaining a sudden release. A false «dangerous» forecast forces the implementation of technically unjustified and costly blowout preventive measures. The modern mine methane flowmeter CoalAwakeningBeast was developed based on the hot-wire measurement principle and with electronic information processing. The device has a flow sensor passage section increased by orders of magnitude, not clogged with dust, dust coal and water. The hot-wire sensor works stably even in the presence of dust. Digital processing of the measurement signal, as well as the accumulation and presentation of reliable information obtained by the mine flowmeter, significantly increase the accuracy of the current outburst hazard forecast. The conditions are being created for a significant reduction in the danger of working in the deep coal mines. Metrological software for electronic flowmeters was created and certified, including a reference installation and a method for checking the device with clean air (instead of methane). This makes the technological processes of adjustment and verification in the plant safe. The device is produced in an explosion-proof version. Mine tests confirmed its advantages in difficult conditions of outburst and especially outburst coal seams. It is recommended to use this flow meter in the mines instead of pressure meters.
Implementation of Digital Twin Technology in the Occupational Risk Management System of an Enterprise
Authors:   Don State Technical University, Maslensky V.V. , Ryabova N.V. ,   Don State Technical University
Published: February 2023

The technology of digital twins has wide possibilities in comparison with the standard work processes, finding an increased application in a wide variety of human activities. The main advantage of this technology is the increase in the efficiency of production processes due to the transition from a large number of full-scale tests, which require significant costs, to mathematical and computer modeling. The article demonstrates the results of using the digital environment to perform a rather time-consuming process of occupational risk assessment. The mathematical model introduced into the digital environment for assessing the components of occupational risk makes it easy to carry out a quantitative and qualitative analysis of the danger and harmfulness of any production process. The method of integral assessment of working conditions was taken as the basis for the mathematical model, the essence of which is to assess the risk of the complex impact of harmfulness and hazards identified in the workplaces. As a result, using appropriate software (for example, Excel), it is possible to upload data on the results of a special assessment of working conditions and expert analysis of scenarios of possible incidents and the consequences of their implementation into the system, and almost immediately receive information about the risk of harmful and hazardous effect, thereby bypassing the process of identifying risky production factors. For objects being designed or reconstructed, the digital environment makes it possible to preliminarily assess the state of working conditions at the workplaces, which in the future may become a justification for the use of more efficient means to reduce occupational risks. Thus, the presented digital model allows to optimize the work of employees of the labor protection service, which will ultimately affect the quality of working conditions and the level of occupational risks of employees.
Stress and Coping Among Elderly During The COVID-19 Pandemic in Sulaimanya City in Kurdistan Region of Iraq
Authors: Qadr Yousif Abdalla , Ismail Azad Ali
Published: February 2023

This study aimed to find out the level of stress and coping methods among elderly in Sulaimanya city during the pandemic COVID-19. Through the snowballing sampling method, 394 elders were included to this study. After validation, two scales were used in this study; stress subscale from Depression, Anxiety and Stress Scale (DASS-21) and a culture-bound scale for determining coping methods. The results of this study showed that participants experienced a mild level of stress. Male participants, elders who live with their family, unvaccinated elders, physically passive elders have had higher stress level than female, elderly home, vaccinated, physical active elders. The findings also indicated that spiritual connection was the most common coping method used by the sample. Results of this study are the first and foremost way to share elder's unexpressed messages; it also can be a way for verbalizing their unspoken feelings. These results may also inform the elder's caregivers that elder's stress level and illness anxiety was not very high, strengthening their social support and spiritual connection may help them to reduce their distress into a lesser degree.
Identifying Maritime Ports’ Investment Drivers: The Case of French Local and Regional Ports
Authors: Fredouet Charles H.
Published: February 2023

Ports play an essential role in the production and distribution processes of companies, as well as in the organizations set up by logistics and transportation service providers. But ports are also likely to have to contribute to the development of the territories they are part of. This paper aims at knowing more about how this double challenge impacts the investments made by local and regional ports. To this end, seventeen individual websites and three collective websites of French ports have been surveyed. Results show that the sampled ports and groups of ports have for the most part properly adjusted both to the constraints posed by the public authorities and to the needs and expectations of their current and potential customers.
The Elements of Forming Space Design at the Great Mosque of Nur Sulaiman Banyumas
Authors: Fariz Nizar  , Ilham Nur Utomo
Published: February 2023

Mosque is the most important place of worship for Muslims, especially in Banyumas city which is dominated by the Muslim community. Researchers are interested in conducting research on The Great Mosque of Nur Sulaiman. This mosque is the oldest mosque in Banyumas city. The researcher examined the space-forming elements in mosque buildings from the viewpoint of Design History. The space-forming elements in buildings are very important as a space-forming identity of a building. Therefore, the researcher took the theme "Design of Space-Forming Elements in the Great Mosque of Nur Sulaiman Banyumas". It was to find out whether the Great Mosque of Nur Sulaiman Banyumas still retains its building elements. And whether there are any additions or subtractions to the current building design. The research aims to determine the design elements of the building of the Great Mosque of Nur Sulaiman and to compare the elements design of the previous and current buildings. The benefit of this research is none other than to increase knowledge and study of the architecture of old buildings, especially mosques in Banyumas city
Breast Milk Donor in Islamic Law Perspective: A Study at The Lactashare Foundation Lowokwaru Malang
Authors: M. Taufiq Agiel  , Adji Pratama Putra
Published: February 2023

Breast milk donation is an alternative solution to help mothers who have difficulty producing breast milk to support exclusive breastfeeding. Donor breast milk is given from mothers who have excess supply of breast milk to babies who need breast milk. Breast milk donation can provide many benefits, but it is undeniable that it will be risky for the baby if it is not handled wisely. The purpose of this study is to determine the donor of ASI (Mother's Milk) at the Lactashare Lowokwaru Foundation, Malang in the perspective of Islamic law. This study used a descriptive qualitative method. The location of this research is at Lactashare Foundation St. Bunga December, Green Sapphire No. 10 Jatimulyo Lowokwaru Malang. Data collection techniques used are observation, interviews, and documentation. The results of the study show that the procedure passes through several steps, namely, mothers who wish to donate their breast milk must register themself through the Lactashare application which can be downloaded via the Google Play Store or contact the contact person directly. Then do a health check and mental examination. The procedure is allowed in the Islamic perspective in that some conditions such as an agreement between both parties (donor and recipient) and the donor are physical and mental health. The procedure applied at the Lactashare Lowokwaru Foundation in Malang is still within the path of Islam and maintains the requirements of Islamic law
Resisting the Disability Gaze in Amy Webb’s Picturebook Awesomely Emma
Authors: Almutairi Reham
Published: February 2023

Recently, the (mis)representation of disability and disabled people has become a key topic of conversation within disability studies. These misrepresentations result from the disability gaze—depicting disability and disabled people in literature and popular culture from the perspective of non-disabled people that often cast disabled people in myriad stereotypical representations. Therefore, this study aims to investigate how the disability gaze is negotiated in Awesomely Emma (2020), a children’s picturebook by Amy Webb, illustrated by Merrilee Liddiard. Drawing on disability studies and visual analysis scholarship, this study highlights how the disability gaze is resisted and destabilized in this picturebook by using staring back—a strategy of resistance developed by disabled people that involves looking back at non-disabled people to demand recognition and resist silencing and marginalization. The study demonstrates how Awesomely Emma employs the process of staring back at the visual and verbal levels as a tool for resistance and activism against the rhetoric of disability discrimination and stigmatization, thereby significantly contributing to disability counternarratives. The significance of this study lies in its manifestation of the role the process of staring back can play in transfiguring entrenched, negative ways of disability representation to propose alternative means of understanding and reimagining disability.
The Impact of Collocational Competence on Translation Quality: Literature Review
Authors: Abdelsattar Metwally Amal , M. Hamadp Mona
Published: February 2023

This study reviews the literature on the significance of collocational competence on the quality of translation, being a meaningful lexical relationship between words. Though the value of recognizing collocations in translation is well acknowledged, several earlier studies have underlined students’ lack of collocational competence and the difficulties they encounter when dealing with collocations in the translation process. The current study evaluates previous research in this field and examines the influence of lexical and grammatical collocation knowledge in translation from English into Arabic and vice versa. The significance of this review lies in exploring the importance of a translator’s collocational expertise in accurately translating lexical and grammatical collocations in the target language. This review aims at answering the review question: How does collocational competence affect translation quality? To answer this question, the researchers examined many studies investigating the impact of collocational competence on the quality of translation. The review further aims at increasing awareness of the significance of this aspect of translation accuracy. The review study provides an overview of pertinent terminology and classifications and a brief introduction to the subject. Then follows an overview of the significance of collocations competence for ensuring the quality of the translation. The final section includes recommendations for translation instructors as well as translators. The review’s findings showed a substantial correlation between the quality of the translation and the adequate knowledge of lexical and grammatical collocations.