bluuebunny/crossref_metadata_2025 huggingface dataset:
Aportes de la economía feminista para repensar el magisterio
Authors: Jiménez Narcia Cora
Published: July 2023

En este artículo se presenta una reflexión pedagógica en torno a los aportes del campo de la Economía Feminista para analizar la relación entre feminización, desarraigo y precarización que ha atravesado históricamente la profesión magisterial en México, y su particularidad en el contexto de la pandemia por la covid-19. Este trabajo se deriva de la sistematización de una experiencia de Investigación-Acción colaborativa que orienta el acompañamiento del colectivo docente de una primaria ubicada en un contexto rural de la Ciudad de México, cuya configuración destaca por encontrarse en una región de relevancia socioecológica para la sostenibilidad de la propia ciudad, la alta rotación del colectivo docente y el carácter pluricultural de las comunidades vinculadas. Se destaca la importancia de resignificación del magisterio con perspectiva territorial y de género y se propone la relevancia de “entrar enteras a las aulas”, con los cuerpos y territorios, para avanzar hacia un horizonte educativo en el que la escuela, al poner el cuidado al centro, sea un espacio fundamental para promover la ampliación de derechos de las infancias, pero también del trabajo docente desde un enfoque de educación sexuada justa y con pertinencia socioecológica.
Socialización y pedagogización
Authors: Díaz Villa Mario , Carrillo Hernández Maria Teresa de Jesús
Published: July 2023

Tanto en el campo de la sociología como en el de la pedagogía, los conceptos nucleares de este artículo están vinculados a la constitución de identidades, que se diferencian en términos del cambio histórico en las bases sociales. Así, mientras el concepto de socialización representaba el ordenamiento de la conducta, el carácter, las maneras y formas de relación, que respondían a la racionalidad moderna, la pedagogización representa el descentramiento de las formas de socialización jerarquizadas, mediadas por límites rígidos, y el surgimiento de modalidades de control sutiles, imperceptibles, difusas y aparentemente vacías. Sin embargo, estos conceptos coexisten y se hibridan en el siglo XXI. Ellos son objeto de descripción y análisis en el presente artículo, en el cual se desarrollan algunos aspectos relevantes para comprender su diferencia y esclarecer su papel histórico en la constitución de la identidad y, contemporáneamente, en la domesticación y control del pensamiento. Para efectos analíticos, en primer lugar, nos referiremos al concepto de socialización; en segundo lugar, abordaremos el de pedagogización. Finalmente, planteamos algunas consideraciones para leer críticamente los sistemas de valores y la constelación de imaginarios construidos por la pedagogización, que alimenta estilos de vida flexibles, transitivos, hedonistas, saludables, a través de los cuales el sujeto es sujetado, cooptado y descentrado. El artículo es el resultado del proceso de reflexión teórica que adelantan los autores sobre la relación entre pedagogía y cultura, conceptos interdependientes que han atravesado las diversas formaciones sociales a lo largo de la historia.
Öğretmenlerin Eğitim Programı Okuryazarlığı ve Mesleki Öz-Yeterlik Düzeyleri Arasındaki İlişkinin İncelenmesi
Authors: SARACALOĞLU Asuman Seda , GÜNDÜZ ÇETİN İpek
Published: July 2023

Bu araştırmada öğretmenlerin eğitim programı okuryazarlık seviyeleri ile mesleki öz-yeterlikleri arasındaki ilişkinin araştırılması amaçlanmıştır. Bunun yanı sıra öğretmenlerin eğitim programı okuryazarlığı ve mesleki özyeterlik düzeylerinin kişisel özelliklere göre farklılıkları araştırılmıştır. Araştırmada betimsel tarama modeli ve ilişkisel desen kullanılmıştır. Evreni Aydın İlinde, devlet okullarında görev yapan öğretmenlerden oluşan çalışmanın örneklemini 396 öğretmen oluşturmaktadır. Çalışmada, Kişisel Bilgi Formu, Eğitim Programı Okuryazarlığı Ölçeği, Öğretmen Öz-yeterlik Ölçeği kullanılmıştır. Çalışma kapsamında toplanmış olan veriler SPSS 21 programı ile analiz edilmiştir. Çalışmanın verileri Mann-Whitney U Testi, Kruskal Wallis Testi ve Pearson korelasyon analizleri ile analiz edilmiştir. Çalışmanın bulgularına göre öğretmenlerin eğitim programı okuryazarlığı ve mesleki öz-yeterlikleri yüksek düzeyde bulunmuş ve aralarındaki ilişkinin ise orta düzeyde pozitif yönlü olduğu sonucuna ulaşılmıştır. Ayrıca kadın öğretmenlerin programı okuryazarlığı daha yüksektir ancak mesleki öz- yeterlikte cinsiyete göre bir farklılığa rastlanmamıştır. Mezun olunan okul türü bakımından incelendiğinde, öğretmenlerin ne eğitim programı okuryazarlığı ne de mesleki öz-yeterlik düzeylerinde anlamlı bir farklılığa ulaşılmıştır.
The psychological experience of medical rescuers during the COVID-19 pandemic
Authors: Fonseca Sílvia Monteiro , Cunha Sónia , Silva Márcio , Ramos M. Joaquina , Azevedo Guilherme , Campos Rui , Faria Sara , Queirós Cristina
Published: July 2023

Medical rescuers are the frontline for COVID-19 and their psychological experience and health are major concerns to our society and healthcare system. This study aims to understand how medical rescuers psychologically experienced this pandemic and explore the contributing variables to COVID-19 anxiety. Portuguese medical rescuers (n = 203) answered questions about their COVID-19 experience, the COVID-19 Anxiety Scale, Patient-Health Questionnaire, Perceived Stress Scale, Obsessive-Compulsive Inventory, and Well-Being Questionnaire. Rescuers presented low COVID-19 anxiety and low-moderate levels of fear. Most already faced or were facing changes in their job-related tasks, did not change household and did not feel stigma/discrimination. COVID-19 workplace security measures were considered moderately adequate and low anxiety, depression and obsessive-compulsive symptoms, low to moderate stress and moderate well-being were found. Only COVID-19 fear and security measures, anxiety, depression and obsessive-compulsive symptoms explained COVID-19 anxiety. Overall, findings showed these rescuers were psychologically well adjusted during the pandemic’s initial stages.
Hibernoma: a case report and discussion of a rare tumor
Authors: Galustov A. M. , Sofronov D. I. , Kozlov N. A. , Fedorova A. V. , Batyrova G. S. , Borzov K. A.
Published: July 2023

Intriduction. Hibernomas account for less than 2 % of all benign lipomatous tumors and 1 % of all lipomatous tumors. They are usually found in 20–40-year old adults (the average age of patients is 38 years). The clinical manifestations are painless soft tissue mass that are mostly slow growing; rapid growth is only found in a small number of patients. We present a case of successful surgical treatment of a pathologically confirmed rare lipomatous tumor of large size, which was located in the soft tissues of the thigh.

Clinical case. A 46-year-old woman was admitted to the hospital due to a tumor 20 × 10 × 10 cm in size, that had developed 10 years ago in the anteromedial aspect of the proximal thigh. Furthermore, she had a history of hypoesthesia one month prior to her admission. During surgery, the femoral nerve was found to be compressed by the large tumor. The resultant symptoms probably caused the patient to seek medical care. Resection was performed by careful dissection, femoral nerve and vessels were spared. Histopathological examination and cytogenetics showed findings suggestive of a hibernoma. At the 6-month follow-up local tumor recurrence or metastasis was not found.

Conclusions. Asymptomatic small-sized hibernoma does not require surgical resection or other treatment. When the tumor is too large and/or has the potential to compress the surrounding tissues, timely radical surgical intervention is reuired.
26 años del Plan Director de la catedral de Oviedo´ (XII-1996 / XII-2022)
Authors: Hevia Blanco Jorge
Published: July 2023

En este artículo se indican las 26 intervenciones restauradoras realizadas en la catedral de Oviedo durante el periodo 1996-2022, bajo las pautas señaladas en el Plan Director, incluyendo la estructura, el método de trabajo, los criterios de intervención y los principales contenidos del mismo. También se indican diversos acontecimientos y anécdotas (hechos y fechas) a modo de referencias temporales que van jalonando este largo proceso restaurador.
Los Bermúdez y los Montero: dos sagas de plateros compostelanos unidas por matrimonios
Authors: Pérez Varela Ana
Published: July 2023

Los apellidos Bermúdez y Montero han aparecido hasta ahora relacionados con marcas de piezas de plata en trabajos de naturaleza catalográfica y exposiciones, sin que se supiese prácticamente nada sobre estos orfebres a pesar de que fueron de las familias más sobresalientes de la platería de Santiago en el siglo XIX. A través de nuestro trabajo en el Archivo Municipal, el de la Catedral de Santiago, el de la Real Sociedad Económica de Amigos del País de Santiago y las hemerotecas de la Biblioteca Nacional de Madrid y la Biblioteca Xeral de la USC, donde trabajamos con prensa histórica y documentos industriales, hemos sido capaces de ubicar a un buen número de miembros de estas familias, que hasta ahora desconocíamos que estaban unidas, y además, por dos matrimonios. Gracias a esto hemos podido periodizar aproximadamente sus carreras, determinar sus marcas y cargos públicos como la contrastía de la ciudad o concejalías en el Ayuntamiento, así como hacer acopio de sus obras, proponer su atribución y datación correcta y pautar unas consideraciones estilísticas.
Hierros para la catedral de Plasencia. Domingo de Céspedes y la antigua reja del coro donada por el obispo Vargas Carvajal, una obra documentada y redescubierta
Authors: Méndez Hernán Vicente , Ramos Berrocoso Juan Manuel
Published: July 2023

El obispo Vargas Carvajal encargó a mediados del siglo XVI una reja para el coro de la catedral nueva de Plasencia, una vez que las obras habían avanzado hasta cerrar las bóvedas del primer tramo de las naves. La reja fue contratada en Toledo con el maestro Domingo de Céspedes. La instalación de la misma en su lugar natural hizo que fuera desechada debido a su estrechez, y sustituida por la que haría Juan Bautista Celma a finales del siglo XVI. Sin embargo, la reja de Vargas Carvajal no se perdió, sino que se integró en otras de menor envergadura de la propia catedral, e incluso se reutilizó en sus púlpitos, de los que aportamos una traza inédita realizada en el siglo XVII. Asimismo, y con las piezas que se han conservado, proponemos una reconstrucción de la reja original.
Potential for acclimation of banded-dye murex, Hexaplex trunculus (Linnaeus, 1758) aft er long-term exposure to low pH
Authors:   University of Dubrovnik, Department of Applied Ecology, Grđan Sanja , Dupont Sam , Glamuzina Luka , Bratoš Cetinić Ana
Published: July 2023

Previous work on ocean acidification highlighted contrasting response between marine species and population. This so-called species-specific response was hypothesized to be partly a consequence of local adaptation to the present range of natural variability in the carbonate chemistry. Under that hypothesis, species tolerance threshold should be correlated to its environmental pH niche. This paper aims to evaluate shell growth rate of Hexaplex trunculus, an important predatory gastropod in benthic communities of Mali Ston Bay. A long-term experiment (310 days) was designed to test a range of pH treatments covering present and future pH levels relevant in the context of future ocean acidification (7.95-7.22 pHT) at the sampling site. Sex had an effect on the shell growth rate irrespective of pH, and was only significant after 236 days. As growth rate in all pH treatments followed seasonal patterns correlating to changes in seawater temperature, the data were divided into 3 time periods. A positive relationship between shell growth rate (SGR, mm day-1) and pH was observed for the period 1-59 days (temperature ranging between 26.5 & 18.8 °C), whereas SGR decreased significantly with pH for the following period (60-236 days, temperature ranging between 20.6 & 8.5 °C). After 236 days (temperature ranging between 27.5 & 14.1 °C), there was no significant difference in SGR among pH. Similar temperature was experienced between the first and third period and the difference in response could be explained as a consequence of an acute negative response versus a longer exposure indicating possible potential for acclimation. Our results highlight the modulating effect of temperature and the importance of long-term experiments to better assess impacts of ocean acidification on marine organisms.
Documenting the spatial and temporal expansion of grouper species in the eastern Adriatic Sea (Croatia) through local ecological knowledge of recreational fishermen
Authors:   Split, Croatia, Ugarković Pero , Dragičević Branko
Published: July 2023

Groupers are important predator marine fish species, and also economically important to commercial and recreational fisheries, but threatened by overfishing worldwide. The dusky grouper (Epinephelus marginatus) is the most common species that historically occurred in the southern and central Eastern Adriatic, while other species were mostly restricted to the southern part of the region or were not recorded in the Adriatic Sea. However, the warming of the sea caused by recent climate change has caused some grouper species in the Eastern Adriatic to expand northward. This spread has been poorly documented, largely because rocky coastal habitats, which are less accessible to conventional research methods that often rely on specific fishing gears, have received far less attention than other more accessible habitats i.e. soft bottoms. Reports of recent grouper expansion are primarily anecdotal and mainly based on the extensive observations of recreational fishermen who mainly utilize rocky coastal habitats. In order to gain insight into this phenomenon, we conducted a survey to investigate the distribution of groupers along the Croatian coast of the eastern Adriatic using the Local Ecological Knowledge methodology. Semi-structured interviews were carried out to record fishers' knowledge and perceptions of changes in their catches, as well as personal observations. The data collected provided information on the spatial and temporal expansion of groupers in the eastern Adriatic over the last 60 years, as perceived by local recreational fishermen.
Unusual fi ndings of soft mouth trout Salmo obtusirostris (Actinopteri: Salmonidae) in the marine environment along the middle Eastern Adriatic coast as a consequence of extreme weather events
Authors:   Institute of Oceanography and Fisheries Laboratory for Ichthyology and Coastal Fisheries, Split, Croatia, Tutman Pero , Kennedy Brian , Matić-Skoko Sanja , Ugarković Pero , Hamzić Adem , Bolotin Jakša , Glamuzina Branko
Published: July 2023

The discovery of individuals of softmouth trout Salmo obtusirostris in the marine environment has been recorded several times in the period from 2015 to the present day in the wider area of the Neretva River delta and southern Adriatic coast. Although this phenomenon appears to be happening more frequently along the Adriatic coast, scientific reports regarding family Salmonidae species found in the marine environment are still very rare in the eastern Adriatic, especially for the softmouth trout. The findings reported here represent the first marine records of this endemic freshwater species. An increasing frequency of these findings may indicate that a higher number of individuals are ending up in the coastal environment during heavy storm events or other unusual hydrologic occurrence. Extreme weather conditions have become more frequent in recent years, mainly as a result of climate change and have led to unexpected phenomena and impacts on nature. The long-term effects on fish and community structure of rivers flowing into the sea require further research, as these weather-induced situations can be expected to become more common. Further investigation into the physiological costs and population consequences of these unusual ecological findings is warranted.
The Impact of Intra-Group Relations on the Amount of the Tax on Certain Financial Institutions
Authors: Szczęśniak Paweł
Published: July 2023

This study of a scientific and research nature concerns the structure of the tax on certain financial institutions. The essence of the subject of research as a scientific problem focuses on the assessment of the impact of intra-group relations between companies on the amount of the tax on certain financial institutions. The main objective of the paper is to analyse how intra-group relations are defined in relation to the rules for creating definitions of legal terms. A lack of proper linkage of legal and factual relations between undertakings and the tax law rules, as determined by the legal-dogmatic method and jurisprudence analysis, may lead to discriminatory or preferential differentiation. The article attempts to prove the thesis that in the light of the provisions of the Act on the tax on certain financial institutions, there is a problem of privileging groups of companies in which, in addition to a domestic entity, which is a taxpayer, members are also those having its registered office or place of management outside the territory of the Republic of Poland. The article contains legislative recommendations that should improve the provisions of the Act on the tax on certain financial institutions. Despite the fact that the article deals with a dogmatic analysis of Polish tax law, the conclusions drawn from it may be of universal importance in relation to the principle of equality understood as the obligation to treat entities in a similar situation equally, without differentiations, either discriminatory or preferential.
The Termination of the Employment Contract of a Data Protection Officer under GDPR: Commentary on the Judgment of the Court of Justice of the European Union in Leistritz AG v LH (C-534/20)
Authors: Fajgielski Paweł
Published: July 2023

In the judgment in question, the Court of Justice of the European Union rules that Article 38 (3) GDPR does not preclude national legislation which provides that a termination of the employment contract of a data protection officer is allowed only with just cause, even if the termination is not related to the performance of that officer’s tasks, in so far as such legislation does not undermine the achievement of the objectives of that regulation. In the approving commentary, based on the theses contained in the judgment, the reasons related to the performance of the data protection officer tasks and other reasons for the inspector’s dismissal are discussed. Doubts related to the dismissal of the data protection officer due to the reorganization of the company are also highlighted. The issue of dismissal of the data protection officer is of great practical importance, the considerations and conclusions presented in the commentary may be helpful for many controllers.
Mueve la lengua, que el cerebro te seguirá. 75 acciones lingüísticas para enseñar a pensar ciencias
Authors: Soler Garcia Jordi
Published: July 2023

Reseña. Domènech Casal, J. (2022). Mueve la lengua, que el cerebro te seguirá. 75 acciones lingüísticas para enseñar a pensar ciencias. Graó.
Africanismos léxicos en la historia lexicográfica de Uruguay: acepciones, usos y etimologías
Authors: Alvarez López Laura , Coll Magdalena
Published: July 2023

El presente artículo estudia palabras de origen africano con registro lexicográfico en Uruguay centrándose en dos extremos cronológicos: el primer diccionario publicado en Uruguay en 1890, Vocabulario Rioplatense Razonado, y el más reciente, Diccionario del Español del Uruguay, de 2011. Describe el recorrido de 14 voces por la lexicografía uruguaya elicitando variantes, derivados, significados, marcas e informaciones sobre su origen y uso. Verifica si se han recogido en la lexicografía del portugués y presenta posibles étimos de lenguas africanas. Para concluir, destaca que la mayoría de las voces figuran en el diccionario más reciente, que son de origen bantú y que, probablemente, entraron al español uruguayo a través del portugués. Constata igualmente que algunas no se alejan de su significado de origen, mientras que otras han evolucionado de manera particular en el español del Uruguay.
Baroja, Besses y el lenguaje informal
Authors: Carbonell Basset Delfín
Published: July 2023

Pío Baroja publicó su novela La busca en 1904, donde refleja la vida popular madrileña de aquel momento y emplea el lenguaje informal de la gente humilde en su lucha por la vida. Luis Besses publicó su Diccionario de argot español en 1905, que marcó un pequeño hito lexicográfico en el estudio del lenguaje jergal español. El vasco no pudo utilizar la obra de Besses y recopiló las voces argóticas de la vida misma, haciendo trabajo de campo. Besses no empleó la novela para recopilar palabras, y aquí se comparan los dos títulos, y se demuestran las coincidencias lexicográficas de ambos, poniendo énfasis en la seriedad y buen hacer de los dos, a la par que se verifica la actualidad de 40 vocablos, de los 60 estudiados, y su devenir en el tiempo.
Technological and Economic Optimization of Honeybee (Apis mellifera L.) Colony Production
Authors: Puškadija Zlatko , Ranogajec Ljubica , Jaman Filip , Bošković Ivica , Kovačić Marin
Published: July 2023

Zbog povećanih gubitaka pčelinjih zajednica, potražnja za njima raste iz godine u godinu. Kako bi nadoknadili izgubljene pčelinje zajednice ili povećali veličinu pčelinjaka, pčelari moraju kupiti nove zajednice ili ih mogu sami proizvesti tijekom sezone. Cilj ovoga rada bio je ispitati tehnološku i ekonomsku učinkovitost triju različitih metoda proizvodnje pčelinjih zajednica: korištenjem jednoga, dvaju i četiriju okvira saća s poklopljenim leglom i pripadajućim pčelama kojima je dodana sparena matica. Istraživanje je provedeno u sjeveroistočnoj Hrvatskoj od svibnja 2019. do travnja 2020. Na kraju prve sezone nije bilo značajnih razlika između skupina u broju okvira zauzetih leglom i pčelama. Proizvodnja zajednica s jednim okvirom poklopljenoga legla omogućuje pčelaru proizvodnju većega broja pčelinjih zajednica, dok su se pčelinje zajednice proizvedene na početku sezone s pomoću četiriju okvira poklopljenoga legla dovoljno razvile i proizvodile med tijekom glavne ljetne pčelinje paše. Sva tri načina proizvodnje pčelinjih zajednica pokazala su pozitivan ekonomski rezultat i stopu isplativosti.
Baseline and 1-Year Follow-Up Data of Patients with End-Stage Hallux Rigidus Treated with an Arthrodesis Reported to Swefoot
Authors: Cöster M C , Osbeck I , Montgomery F , Cöster-Stoij M E
Published: July 2023

Background: Hallux rigidus (HR) affects the first metatarsophalangeal joint and is the most common osteoarthritic condition in the foot. The most used surgical treatment for severe cases of HR is an arthrodesis. The aim of this study is to describe patient characteristics, surgical treatment and the patient-reported outcomes for patients treated with arthrodesis for HR using data from Swefoot, the Swedish quality register for foot and ankle surgery. Methods: From Swefoot we extracted data on patients who underwent surgery for HR between January 2014 and December 2019. We included 419 patients with end-stage HR, who had not previously been treated surgically for HR on the same side. The outcome was measured with the Self-reported Foot and Ankle Score (SEFAS) (summary score 0-48) and EuroQol 5 Dimensions (EQ5D) (index 0-1) together with questions regarding appearance, shoe wear and satisfaction. We extracted surgical and patient-reported data preoperatively and 1 year postoperatively. Results: Our patient-population is predominantly female, around 61 years old, and slightly overweight. The arthrodeses are most often fixated with screws and most of the patients are allowed to bear weight immediately after surgery. The mean SEFAS score is 22 preoperatively and 38 postoperatively, the corresponding values for EQ5D index are 0.56 and 0.81 which means that the health-related quality of life (HrQoL) improves significantly after surgery. Conclusion: Patients with severe HR treated with an arthrodesis have reduced pain, improved function and HrQoL according to the patient-reported outcome measures SEFAS and EQ5D. The mean postoperative SEFAS value was close to the mean SEFAS value of the Swedish general population in the same age category. Fixation techniques and postoperative regimen differ among surgeons in the country. This is the first report from Swefoot regarding this patient population.
Prenatal Stress and Endo-crine Disrupting Chemical Exposure: Hypothalamic-Pituitary-Adrenal Axis Dysregulation as a Mecha-nism for the Health Conse-quences of Both
Authors: Hall Julianne , Mercugliano Christina , Conti Lisa
Published: July 2023

During the past several decades there has been increasing attention to the risks of exposure to endocrine disrupting chemicals, agents that mimic or block the effects of endogenous hormones. Previous research demonstrates that there may be critical periods of development where factors such as prenatal stress and endocrine disrupting chemical exposure can result in endocrine system dysregulation which manifests both immediately and later in life. This review describes the types of common endocrine disrupting chemicals and routes of exposure, the structure and functions of the hypothalamic-pituitary-adrenal axis and its role in the physiological response to stress, and highlights the current evidence showing that endocrine disrupting chemicals may alter normal hypothalamic-pituitary-adrenal axis functions. These topics are unified upon discussion of evidence indicating that prenatal endocrine disrupting chemical exposure has many of the same effects as prenatal stress on the hypothalamic-pituitary-adrenal axis, leading to long-term dysregulation of the axis and subsequent alterations in physiological responses to stress. We further suggest that prenatal endocrine disrupting chemical exposure in combination with prenatal stress may result in additive, if not synergistic effects on the hypothalamic-pituitary-adrenal axis-mediated stress response. Finally, we discuss vulnerable populations at an elevated risk for dual stress and endocrine disrupting chemical exposure and emphasize critical areas for future research.
Correspondence of yolk sac and embryonic genotypes in F0 mouse CRISPants
Authors: Fuselier Kayla , Kruger Claudia , Salbaum J. , Kappen Claudia
Published: July 2023

CRISPR-mediated genome editing in vivo can be accompanied by prolonged stability of the Cas9 protein in mouse embryos. Then, genome edited variant alleles could potentially be distributed differentially to the cell lineages that are specified early during morula and blastocyst development. This has practical implications for the investigation of F0 generation individuals, as cells in embryonic and extraembryonic tissues, such as the visceral yolk sac, might end up inheriting different genotypes. We investigated the possible scenarios, and here report that, most commonly, embryonic and yolk sac genotypes are congruent even when the conceptus is a chimera. Nevertheless, low abundance of a variant allele may represent a private yolk sac mutation, and in those rare cases, the mutational status of the embryo proper should be determined with additional genotyping.
The Glioblastoma Landscape: Hallmarks of Disease, Therapeutic Resistance, and Treatment Opportunities
Authors: Boylan Jack , Byers Elizabeth , Kelly Deborah
Published: July 2023

Malignant brain tumors are aggressive and difficult to treat. Glioblastoma is the most common and lethal form of primary brain tumor, often found in patients with no genetic predisposition. The median life expectancy for individuals diagnosed with this condition is 6 months to 2 years and there is no known cure. New paradigms in cancer biology implicate a small subset of tumor cells in initiating and sustaining these incurable brain tumors. Here, we discuss the heterogenous nature of glioblastoma and theories behind its capacity for therapy resistance and recurrence. Within the cancer landscape, cancer stem cells are thought to be both tumor initiators and major contributors to tumor heterogeneity and therapy evasion and such cells have been identified in glioblastoma. At the cellular level, disruptions in the delicate balance between differentiation and self-renewal spur transformation and support tumor growth. While rapidly dividing cells are more sensitive to elimination by traditional treatments, glioblastoma stem cells evade these measures through slow division and reversible exit from the cell cycle. At the molecular level, glioblastoma tumor cells exploit several signaling pathways to evade conventional therapies through improved DNA repair mechanisms and a flexible state of senescence. We examine these common evasion techniques while discussing potential molecular approaches to better target these deadly tumors. Equally important, the presented information encourages the idea of augmenting conventional treatments with novel glioblastoma stem cell-directed therapies, as eliminating these harmful progenitors holds great potential to modulate tumor recurrence.
Ahifen: A critical review
Authors: Sharma Preeti
Published: July 2023

Poppy, a plant belonging to the papaveraceae family, is the source of opium.It is a plant that blooms. It has sedative, somniferous, and neurotoxic properties in addition to being cerebrally poisonous. Due to its neurotoxic nature, opium causes a variety of adverse effects, including anxiety, seizures, hallucinations, sleepiness, giddiness, and many more. In order to create various types of analgesic medications to cure pain and promote sleep, this poppy is grown as an agricultural crop. The main source of opium, or dried latex made by the seed pods, is the opium poppy, as its name suggests. Because opium has sexual properties, many people use it for extended periods of time before becoming addicted.
Improvement in renal function of Hyperhomocysteinemic rats by panax ginseng
Authors: Singh Kuldeep , Gupta Jeetendra Kumar , Kumar Shivendra , Mukherjee Soumyadip , Kumari Sonal , Kumari Meena , Anurag  , Singh Talever , Singh Krishanveer
Published: July 2023

Hyperhomocysteinemia is a condition characterized by elevated levels of homocysteine in the blood, which has been linked to various cardiovascular and renal complications, including impaired renal function. , a widely used medicinal herb, has been shown to possess antioxidant, anti-inflammatory, and vasoprotective properties. However, its potential role in improving renal function in hyperhomocysteinemic conditions remains largely unexplored.

Hyperhomocysteinemia is a metabolic disorder characterized by elevated levels of homocysteine in the blood, which is associated with impaired renal function. This study aimed to investigate the potential therapeutic effects of Panax Ginseng on renal function in hyperhomocysteinemic rats.

Male Wistar rats There were five animals per group. Group 1 functioned as the control group, receiving a typical meal (chow feed) and unlimited water. L-methionine (1.7 g/kg/day, p.o.) was given to group 2 Hyperhomocysteinemia (HHCY Control) once daily.

A modest dosage of Panax ginseng (50 mg/kg body weight) and L-methionine (1.7 g/kg/day, p.o.) was administered orally to the third group (test drug 1). The fourth group (test drug 2) got the same combination of L-methionine (1.7 g/kg/day, p.o.) and Panax ginseng (high dosage, 100 mg/kg body weight). In addition, the second, third, and fourth groups of rats received intraperitoneal doxorubicin injections at a dosage of 5 mg/kg after 1 hour of L-methionine administration at intervals of 15 days in order to produce Hyperhomocysteinemia-mediated nephrotoxicity. After 28 days of the trial, the animals were slaughtered, and the blood levels of homocysteine, creatinine, and urea were measured. We measured the amounts of urea, creatinine, and homocysteine in the serum.

administration effectively improved renal function and attenuated histopathological changes in hyperhomocysteinemic rats. These findings suggest that Panax Ginseng may have a renoprotective effect in Hyperhomocysteinemia-induced renal dysfunction.
Atypical childhood Takayasu arteritis – A case report
Authors: Appaswamy Shruti , Pandey Neha , Ghildiyal Radha
Published: July 2023

Childhood Takayasu arteritis is one of the most common vasculitis in paediatric age group. It predominantly involves the greater vessels such as aorta and its branches, leading to granulomatous inflammation. The process of inflammation gives rise to the symptoms based on thrombotic or aneurysmal phenomena. This is a case report of a 11-year-old girl diagnosed in an urban tertiary care centre in India with childhood Takayasu arteritis. The said child had first presented with non-specific symptoms such as leg ache, back ache and fever. Over the course of illness, the child developed hypertension and had also suffered from PRES (posterior reversible encephalopathy syndrome). Clinical examination was consistent with Takayasu arteritis, however with predominant medium-sized vessel involvement on imaging. Since this is a relatively atypical presentation, it was mandatory to rule out other causes of medium-vessel arteritis, especially DADA2 (deficiency of ADA2).
Features of US foreign policy in the South Caucasus at the present stage
Authors: BUTOROV ALEXEY
Published: July 2023

The article examines the foreign policy, the main priorities and the economic direction of the United States in the South Caucasus region. The geopolitical, geostrategic and geo-economic role of the South Caucasus in the general system of international relations is highlighted. The article analyzes the current state of bilateral political and economic relations between the United States and Azerbaijan, Armenia and Georgia.
The American concepts of the settlement of The Ukraine crisis
Authors: Podlesny Pavel
Published: July 2023

The goal of the article is to explore main approaches of the American experts and politicians of the settlements of the Ukrainian crisis, to and analyze their contents and the possible of the extent of their influence on the USA policy on this problem.
Patrón de riqueza de flora y vegetación del páramo El Romeral - macizo de Santurbán
Authors: Galván-Carvajal Sandra Y. , Ortiz-Rodríguez Nelcy Y. , Pinto-Zárate Jairo , Rangel-Ch. J. Orlando , Sánchez Roberto
Published: July 2023

A partir de los inventarios detallados del componente vegetal del páramo de El Romeral Cucutilla, Norte de Santander, y California, Santander (07°22’-07°24’ N, 72°51’- 72°05’ W, entre los 3400 y los 3920 m), se registraron 252 especies agrupadas en 157 géneros y 72 familias de plantas con flores, helechos y briófitos. Se encontraron 190 especies de 120 géneros y 45 familias entre las plantas con flores (grupo mayoritario). En la caracterización de la vegetación con enfoque fitosociológico se determinaron la clase Orthrosantho chimboracensis-Calamagrostietea effusae, el orden Vaccinio floribundi-Chusquetalia tessellatae y cuatro alianzas. La alianza con mayor número de asociaciones (cuatro) fue Espeletio conglomeratae-Chusqueion tessellatae. En la distribución de la vegetación a nivel de alianza se diferenció un patrón de los sitios de suelos húmedos-encharcados asociados con un microclima muy húmedo donde predominó Chusquea tessellata, como en las alianzas Carici pygmaeae-Chusqueion tessellatae y Espeletio conglomeratae-Chusqueion tessellatae. En sitios asociados con fases de transición en la humedad del suelo (áreas bien drenadas) disminuyó la importancia ecológica y la frecuencia de aparición de Chusquea tessellata, como en la alianza Acaeno elongatae-Hypericion phelli, en tanto que en sitios secos se encontró vegetación de la alianza Arcytophyllo mutici-Calamagrostion effusae, en la que generalmente están ausentes elementos característicamente ligados a las condiciones de humedad-encharcamiento del suelo. La vegetación era de porte bajo con mayor cubrimiento de los estratos herbáceo (dominante) y rasante. El número total de especies varió entre 26 Niphogetonis ternatae-Chusqueetum tessellatae y 37 Hyperico phelli-Puyetum bicoloris, sintaxón que igualmente presentó el mayor índice de riqueza (77x10-2).
Nanociencia, nanotecnología y tecnologías disruptivas en el contexto de la medicina de precisión
Authors: Orozco Jahir
Published: July 2023

El cuidado de la salud está experimentando un cambio de paradigma con respecto al diagnóstico y manejo de enfermedades orientado a llevar la medicina y la atención personalizadas a quienes lo necesitan. En este sentido, las ciencias puras han encontrado aliados en la nanociencia, la nanotecnología y otras tecnologías convergentes y disruptivas para asumir tan exigente tarea. Aquí se ilustra cómo dicha convergencia puede generar soluciones sin precedentes en el cuidado de la salud, por ejemplo, con el uso de nanobiosensores electroquímicos para monitorear patógenos y biomarcadores multiparamétricos a diferentes niveles moleculares y dilucidar el estado de salud de un individuo de manera personalizada. Se presentan, asimismo, ejemplos de nanobiosensores electroquímicos explorados para el diagnóstico, su potencial para el pronóstico y la posible evaluación del riesgo de complicaciones en pacientes. En este contexto, los diagnósticos inteligentes juegan un papel crucial en el cuidado de la salud 4.0, ya que puede avanzarse desde los datos inteligentes hacia dispositivos de diagnóstico capaces de analizar macrodatos que se beneficien del Internet de las cosas, el aprendizaje automático, el aprendizaje profundo y los teléfonos inteligentes entre otras tecnologías convergentes y disruptivas de vanguardia. Además, el trabajo destaca el potencial de los nanoportadores funcionales para la administración controlada y específica de fármacos como una rama de la medicina personalizada que promete revolucionar la atención médica. Por último, se hacen algunas reflexiones sobre medicina traslacional, así como comentarios finales y el recuento de los desafíos que implica llevar masivamente esta nueva y revolucionaria tecnología a los sistemas de salud globales.
Um estudo sobre a tripartição dos setores dos apartamentos em João Pessoa
Authors: Olveira Patrícia , Silva Maísa Beatriz , Costa Joana Darc , Meira Alexsandra
Published: July 2023

Na Idade Média, a Europa tinha habitações que se apresentavam como um grande espaço, onde se realizavam atividades de cozinhar, comer, dormir, etc. Em meados do século XIX, essas habitações começaram a reproduzir os padrões burgueses parisienses, caracterizados pela tripartição. A esse modelo de partição coube o papel de fragmentar a habitação nos setores: social, íntimo e de serviços. Desta feita, este artigo objetiva analisar os apartamentos de João Pessoa entre 2006 e 2011, com foco nessa tripartição burguesa da habitação. Para tanto, a princípio, levantou-se o número de prédios residenciais em construção, a partir de 4 pavimentos, obtendo-se o universo de 597 empreendimentos, do qual retirou-se uma amostra de 240 edificações. Coletou-se plantas de folders ou de projetos obtidos diretamente com construtoras, que foram lançadas no AUTOCAD e analisadas tipologicamente. A partir dessas análises, buscou-se verificar as mudanças ocorridas nos apartamentos, tais como: percentuais de áreas destinadas a cada setor e quantidade de cômodos. Percebeu-se que a influência da tripartição burguesa na habitação ainda é muito forte desde os apartamentos mais simples aos de padrão mais elevado. Comprovou-se isso a partir da quantidade de apartamentos separados em setores funcionais.
Uma metodologia para implantação de um Sistema de Gestão de Segurança da Informação (SGSI) baseado nas normas ABNT NBR ISO/IEC 27001 e 27002
Authors: Mendes Ricardo Ribeiro , Oliveira Rômulo R. L. de , Costa Anderson Fabiano Batista Ferreira da , Gomes Reinaldo Cezar De Morais
Published: July 2023

A segurança da informação destaca-se como uma das principais preocupações em diversas organizações. Para garantir que as informações e os sistemas de informações estejam protegidos contra ameaças de todos os tipos é necessário definir processos gerenciados e assegurar a confidencialidade, integridade e disponibilidade delas. Com esta finalidade, as normas ABNT NBR ISO/IEC 27001 e ABNT NBR ISO/IEC 27002 provem um conjunto de técnicas para estabelecer, implementar, operar, monitorar, analisar criticamente, manter e melhorar um Sistema de Gestão de Segurança da Informação (SGSI). Porém, ainda é preciso definir uma metodologia para aplicar os conceitos identificados nas normas. Este artigo traz uma metodologia para implantar um SGSI, tomando como base a ABNT NBR ISO/IEC 27001 e 27002 simplificando o processo de planejamento, implantação, análise crítica e modificação do sistema. Através do modelo sugerido, será possível classificar a informação, identificar os riscos relevantes que atingem as informações, selecionar controles das normas e construir um plano de ação para a implantação do SGSI em qualquer tipo de organização.
Filmes produzidos com compostos de tungstênio para aplicações elétricas e optoeletrônicas: uma revisão
Authors: Siqueira Nívia Luciana Costa de , Chibério Paulo Henrique , Dantas Neto João De Medeiros , Silva Vamberto Monteiro da , Acchar Wilson
Published: July 2023

Os materiais à base de tungstênio têm despertado interesse nos últimos anos devido às suas propriedades únicas e à possibilidade de utilização em uma ampla gama de aplicações. Em vista disso, neste trabalho, foi realizada uma revisão sistemática da literatura (RSL) acerca de filmes produzidos com compostos de tungstênio como material base. Foram analisados os métodos de deposição empregados na confecção dos filmes bem como as propriedades elétricas, dielétricas e optoeletrônicas estudadas nos trabalhos analisados, as principais aplicações estudadas e/ou sugeridas, composição do filme, entre outros aspectos. As buscas foram realizadas nas plataformas: Periódicos CAPES, Science Direct, Scopus e Google Acadêmico. Os critérios de análise, seleção e exclusão de trabalhos foram definidos de acordo com a estratégia PICO – População, Intervenção, Comparação e Resultados (outcomes). Na primeira etapa da busca, foram encontrados 187 artigos, dos quais 36 foram selecionados para leitura integral após a aplicação dos referidos critérios. O método de produção mais utilizado foi o Sputtering, seguido dos de Deposição de Vapor Químico (DVQ), Sol-gel e Tape Casting. As principais propriedades estudadas nos trabalhos foram a resistividade elétrica e a curva IV. Quanto à composição, o trióxido de tungstênio foi o composto mais investigado nos trabalhos sobre confecção dos filmes. A aplicação mais indicada foi em dispositivos eletrocrômicos, como películas para janelas inteligentes, displays e outras aplicações optoeletrônicas. Também foram indicadas aplicações como supercapacitores, células solares, sensores, armazenamento de energia e fotodetectores. Com base nos artigos analisados, é possível afirmar que filmes de tungstênio possuem propriedades interessantes para diferentes aplicações, sendo um material versátil e com potencial para mais investigações.
Kia Takatū ā-Matihiko: Final evaluation report
Authors:   NZCER, Bolstad Rachel , Bright Nicola
Published: July 2023

Kia Takatū ā-Matihiko, the National Digital Readiness Programme, was a bilingual and bicultural programme designed to support teachers, kaiako, principals, and tumuaki to feel confident and well equipped to be ready to implement the new Digital Technologies and Hangarau Matihiko (DT & HM) curriculum content. Based on NZCER's evaluation findings, we identified several key messages to support the Ministry of Education’s ongoing and future design plans for any nation-wide PLD support approach.
Educação Permanente em Saúde: implementação do protocolo gerenciado da sepse em uma Unidade de Pronto-Atendimento
Authors: Oliveira Sousa Matheus , Gomes de Andrade Aryândelly , Angélica Da Hora Raquel , Emanuel dos Santos Lucas , Fernando Silva Cardoso Luiz , Caires Moreira Dos Santos Izabelle , Cristina de Souza Arcanjo Keite , Regina de Oliveira Pedroso Márcia , Lidiany Tributino de Souza Maria
Published: July 2023

A Educação Permanente em Saúde é caracterizada pela inserção dos sujeitos no processo de aprendizagem, tornando a formação dos profissionais de saúde um processo importante na qualidade do cuidado e na segurança do paciente. Uma das maiores demandas das Unidade de Pronto-Atendimento é o tratamento por infecções bacterianas que atinge tanto o público mais idoso quanto o mais jovem, sendo esse espaço um local propício para o desenvolvimento de estratégias que visem melhorar a identificação precoce e realizar o acompanhamento necessário desses casos. O presente artigo tem como objetivo relatar a experiência de discentes do Programa de Educação para o Trabalho em Saúde da Universidade Federal do Oeste da Bahia e da Secretaria Municipal de Saúde em uma Unidade de Pronto Atendimento, durante o período de julho a dezembro de 2022, de forma a colaborar na construção da gestão do cuidado de Sepse. Discentes dos cursos de Ciências Biológicas, Farmácia, Medicina e Nutrição tiveram a oportunidade de auxiliar nas quatro fases pertencentes ao Protocolo Sepse: Reconhecimento, Ressuscitação, Reavaliação e Referenciamento. Ao final, foram realizados oficinas, treinamentos e produção de materiais que auxiliaram a equipe profissional da pronto-atendimento e do Programa Melhor em Casa na prevenção do quadro de Sepse, assim como identificação e tratamento precoce dos casos existentes. O envolvimento dos estudantes colaborou na gestão do cuidado dos casos de sepse no município ao integrar protocolos pautados cientificamente em práticas atualizadas e oportunizar a ampliação dos saberes e rotinas profissionais a partir da Educação Permanente em Saúde.
Influence of additives of carbon nanotubes and graphene to the active mass of the negative electrode of the lead-acid battery on its electrochemical characteristics
Authors:   Saratov State University, Burashnikova Marina M. , Panshin Egor V. ,   Saratov State University
Published: July 2023

The electrochemical characteristics of the negative electrodes of the lead-acid battery with additives of carbon nanotubes and graphene were studied. It was shown that the highest values of the capacitive characteristics of the electrodes were obtained by adding carbon nanotubes to the negative active mass. The processes occurring on the negative electrode were studied by the method of impedance spectroscopy. Applying simulation, an equivalent electrical circuit was obtained, which adequately approximated the obtained frequency dependences. The elements of the proposed equivalent circuit were calculated. It was found that the injection of carbon additives increases the resistance R3 related to the porous structure of the electrodes.
Internet as an element of modern social infrastructure: Sociological and territorial aspects
Authors:   Saratov State University, Molochko Anna V. , Andryuschenko Polina A. ,   Saratov State University
Published: July 2023

The article is devoted to the analysis of the ways of using and accessing the Internet. In the course of the study, a sociological survey of respondents living in the city of Saratov was conducted, the results of which were compared with the average Russian statistical data.