bluuebunny/crossref_metadata_2025 huggingface dataset:
PENINGKATAN KUALITAS PEMBELAJARAN MELALUI KEGIATAN LESSON STUDY DI UNIVERSITAS MAJALENGKA
Authors: Santoso Erik
Published: July 2020

Lesson study is a continuous activity that can be applied through study groups. The purpose of this service is to determine the quality of learning through lesson study activities. The method of implementing the activity is based on the three steps of lesson study activities namely plan, do and see. Planning is the starting point as a key to success in learning. The conclusion from this implementation activity that Lesson study, if it becomes a culture in a learning group, can create a good learning climate. Through ongoing lesson study activities, the quality of learning carried out by educators can improve as well.
PENINGKATAN KAPASITAS BADAN USAHA MILIK DESA (BUMDes) MAPAN DESA PANJALIN KIDUL
Authors: Sudirno Dadang , Masduki Masduki , Suparto L , Nahdi Dede Salim , Sumianto Toto
Published: July 2020

Badan Usaha Milik Desa atau disebut BUMDes pada dasarnya merupakan pilar kegiatan ekonomi di desa yang berfungsi sebagai lembaga sosial juga komersial. Sebagai sebuah usaha desa, pembentukan BUMDes adalah benar-benar untuk memaksimalisasi potensi masyarakat desa baik itu potensi ekonomi, sumber daya alam, ataupun sumber daya manusianya. Dalam perkembangannya keberadaan BUMDes di daerah termasuk di Kabupaten Majalengka, khususnya di Desa Panjalin Kidul, mengalami pasang surut disebabkan banyak faktor diantaranya, rendahnya kapasitas manajerial, kurangnya Pemberdayaan masyarakat lokal, dan Infrastruktur BUMDes belum optimal. Bumdesa Mapan Desa Panjalin Kidul memiliki potensi untuk berkembang karena memilki sumberdaya manusia (pengurus), dukungan keuangan serta aset yang dapat dimamfaatkan. Namun karena  masih minimnya pengetahuan pengurus dalam menjalankan BUMDesa, menyebabkan BUMDesa belum dapat berfungsi dengan optimal. Kegiatan pengabdian ini dilaksanakan dengan metode sosialisasi dan pelatihan. Dari kegiatan ini diperoleh hasil bahwa hampir seluruh peserta memahami dan memiliki kemampuan dalam melakukan pengelolaan BUMDes.
MENINGKATKAN KOMPETENSI PROFESIONAL GURU MELALUI PENGEMBANGAN MEDIA PEMBELAJARAN BERBASIS TEKNOLOGI INFORMASI
Authors: Nahdi Dede Salim , Rasyid Abdur , Cahyaningsih Ujiati
Published: July 2020

Kegiatan pengabdian  pada masyarakat  berupa pendampingan  dalam pengembangan media pembelajaran ini bertujuan untuk memberikan pengetahuan dan keterampilan dalam pengembangan media pembelajaran untuk meningkatkan kompetensi professional guru. Sasaran  dalam  kegiatan  pelatihan ini  adalah  guru-guru  sekolah dasar di Kecamatan Cingambul.  Pendampingan dalam pengembangan media pembelajaran dilakukan dengan metode ceramah,  demonstrasi  dan  latihan  yang  disertai  tanya  jawab.  Metode ceramah digunakan untuk menjelaskan konsep pengantar guru profesional dan sertifikasi  guru serta teori media pembelajaran.  Metode demonstrasi dipakai untuk menunjukkan suatu proses kerja yaitu tahap-tahap pengembangan   media   pembelajaran   berbasis   komputer,   sedangkan metode  latihan  untuk  mempraktikkan  pembuatan  media  yang memenuhi persyaratan program sertifikasi guru. Sementara metode tanya jawab untuk memberi kesempatan para peserta berkonsultasi dalam mengatasi kendala dalam pengembangan media pembelajaran. Manfaat yang dapat diperoleh peserta dari kegiatan pelatihan ini antara lain dapat mengembangkan media pembelajaran berbasis komputer sesuai mata diklat yang diampu.
PENGEMBANGAN SEKOLAH RAMAH ANAK DI TINGKAT PENDIDIKAN ANAK USIA DINI
Authors: Tusriyanto Tusriyanto
Published: July 2020

Fase anak usia 0-6 tahun (golden age) adalah masa dimana anak harus mendapatkan pendidikan khusus agar pertumbuhan dan perkembangan fisik maupun mentalnya secara tepat agar mampu menerima dan memberi respon terhadap stimulasi yang didapatkan dari lingkungan. Hal terpenting yang harus dilakukan pengelolan pendidikan khususnya di tingkat Pendidikan Anak Usia Dini adalah mengupayakan Sekolah Ramah Anak (SRA). Sekolah ramah anak diartikan sebagai sebuah konsep sekolah yang terbuka, berusaha mengaplikasi pembelajaran yang memperhatikan perkembangan psikis maupun psikologis siswanya. Pengembangan SRA dapat dilaksanakan pada Pendidikan Anak Usia Dini (PAUD), melalui kerjasama dari keluarga, masyarakat maupun sekolah.
BUDAYA DALAM DAKWAH WALI SONGO
Authors: Mujib Abdul
Published: July 2020

Pertumbuhan dan Perkembangan Islam pada periode awal ditandai adanya temuan nisan makam Fatimah binti Maemun (wafat 1082 M), di Leran, Gresik, Jawa Timur. Estafeta dakwah islamiyah tak kenal henti hingga silih berganti lahirnya sejumlah tokoh yang handal, antara lain Wali Songo, mereka adalah Maulana Malik Ibrahim di Gresik, Sunan Ampel di Surabaya, Sunan Giri di Gresik, Sunan Bonang di Tuban, Sunan Drajat di Lamongan, Sunan Kudus di Kudus, Sunan Muria di Kudus, Sunan Kalijaga di Kadilangu Demak, dan Sunan Gunung Jati di Cirebon. Sukses-sukses besar dakwah islamiyah telah memberikan keteladanan antara lain dalam aspek ekonomi. Melalui kekuatan ekonomi, Islam di Pulau Jawa bangkit melahirkan kekuatan politik dalam wujud Kesultanan Demak. Kehadiran Kesultanan Demak tidak terlepas dari peran Wali Songo yang dianggap sebagai pimpinan dari sejumlah besar muballigh Islam dalam dakwah islamiyah di daerah-daerah di Pulau Jawa.
AKULTURASI BUDAYA JAWA SEBAGAI STRATEGI DAKWAH
Authors: Setyaningsih Rina
Published: July 2020

Budaya sudah melekat dalam masyarakat Indonesia sebelum Islam datang. Terutama di komunitas Hindu-Budha, orang tidak mengenal Islam. Banyak kelompok masih percaya pada animisme-dinamisme. Terutama masyarakat Jawa yang berbau mistis masih sering dilakukan. Budaya dibagi menjadi tiga fase yaitu: budaya Jawa pra-Hindu-Buddha, ciri menonjol dari struktur masyarakat pada waktu itu didasarkan pada aturan hukum adat dan sistem keagamaannya, yaitu animisme-dinamisme yang merupakan inti dari budaya yang mewarnai semua aktivitas kehidupan rakyat. Hukum adat sangat mengikat sehingga masyarakatnya statis dan konservatif. Budaya Hindu Jawa, Pada fase ini proses pengembangan budaya Jawa merupakan pengaruh kuat budaya India (Hindu). Dalam masyarakat Jawa, pengaruh Hindu-Budha bersifat ekspansif, sementara budaya Jawa yang menerima pengaruh dan menyerap unsur-unsur Hindu-Buddha setelah melalui proses akulturasi tidak hanya mempengaruhi sistem budaya, tetapi juga mempengaruhi agama. Dan budaya Jawa dalam fase menyebarkan dan melembagakan propaganda di Jawa. Pada fase terakhir ini Islam telah masuk ke Indonesia dan masyarakat sudah mulai memeluk Islam melalui propaganda dengan media budaya sehingga bisa diterima oleh semua pihak.
Mindfulness-Based Interventions for Schizophrenia
Authors: Hodann-Caudevilla Ricardo M. , Díaz-Silveira Cintia , Burgos-Julián Francisco Alfonso , Santed Miguel Angel
Published: July 2020

Mindfulness-based interventions (MBIs) consist of short and structured intervention protocols focused on teaching patients the use of mindfulness for therapeutic purposes. Over the last three decades, there has been a remarkable expansion of this kind of interventions for the treatment of various psychopathological conditions. Despite this, MBIs have only recently begun to be applied in the treatment of people with schizophrenia. Analysis of the available evidence on MBIs for the treatment of people with this disorder suggests that they are effective and safe treatments, although more research is needed to draw more robust conclusions.
 
Towards high–throughput analyses of fecal samples from wildlife
Authors: Sarabia C. , Salado I. , Cornellas A. , Fernández-Gil A. , Vilà C. , Leonard J. A.
Published: July 2020

High–throughput sequencing offers new possibilities in molecular ecology and conservation studies. However, its potential has not yet become fully exploited for noninvasive studies of free–ranging animals, such as those based on feces. High–throughput sequencing allows sequencing of short DNA fragments and could allow simultaneous genotyping of a very large number of samples and markers at a low cost. The application of high throughput genotyping to fecal samples from wildlife has been hindered by several labor–intensive steps. We evaluate alternative protocols which could allow higher throughput for two of these steps: sample collection and DNA extraction. Two different field sampling and seven different DNA extraction methods are tested here on grey wolf (Canis lupus) feces. There was high variation in genotyping success rates. The field sampling method based on surface swabbing performed much worse than the extraction from a fecal fragment. In addition, there is a lot of room for improvement in the DNA extraction step. Optimization of protocols can lead to very much more efficient, cheaper and higher throughput noninvasive monitoring. Selection of appropriate markers is still of paramount importance to increase genotyping success.
项目管理在建筑工程管理中的应用分析
Authors: 杨 阳
Published: July 2020

在最近的几年时间里，在多方面利好因素的影响下，使得我国社会经济水平得到了显著的提升，从而为建筑工程行业的发展带来了良好的机遇，并且也加剧了建筑工程行业内部的竞争形势。在建筑工程行业中工程管理工作的作用是十分巨大的，其在保证工程施工质量和安全方面具有非常重要的影响作用，并且能够有效的促进整个建筑工程行业持续稳定发展，鉴于此，这篇文章主要针对项目管理在建筑工程管理工作中的切实运用展开全面深入的研究分析，希望能够对建筑工程管理工作的良好发展有所帮助。
招标代理在建筑工程招投标中的作用研究
Authors: 顾 超杰
Published: July 2020

在多方面利好因素的影响下，使得我国综合国力得到了全面的提升，从而为我国建筑工程行业的发展带来了良好的机遇，在这种形势下促进了建筑工程项目招标单位市场主体地位的确定，招标代理机构需要顺应市场经济的发展形势，为项目招标单位给予良好的服务，并且要综合各方面实际情况和需求来对自身的市场定位以及业务覆盖范围给予调整。在最近的几年时间里，我国招投标代理行业取得了良好的发展成绩，并逐渐的扩展了自身的业务范畴，拥有大量的高水平专业人才，这样对于整个招投标行业的发展起到了积极的推动作用。这篇文章主要针对招标代理在建筑工程招投标中作用展开全面深入的研究分析，希望能够对我国招标代理行业的稳定健康发展有所帮助。
液压机械传动控制系统在机械设计及制造中的应用探讨
Authors: 赵 伟
Published: July 2020

近年来，我国加大了改革开放的力度，从而为各个领域的发展壮大带来了良好的机遇，尤其是工业生产行业的发展十分的迅猛，从而推动了我国机械设备制造整体水平的显著提升，促进了液压机械传动控制技术和系统的适用范围的不断扩展。但是在将液压传动控制系统加以实践运用的过程中也会遇到诸多的问题，所以我们还需要对系统的实践运用展开全面深入的研究，从而将液压机传动控制系统的作用充分的发挥出来，为我国机械设备制造行业的稳步健康发展创造良好的基础。
REFLECTION OF DEMOCRATIC VALUE AND ATTITUDE OF STATESMAN IN RAJA NEGERI JAMBI AND MENTIKO BETUAH’S FOLKLORE FUNCTION AND STATEMAN
Authors: Palupi Dian , Prayoga Reza Amarta
Published: July 2020

Folklore is a construction of local wisdom that grows and develops into the basis of the values of social functions. The social function of the political meaning in folklore can be used as the country’s resilience reflection, like democratic learning and strengthening the figure of the statesman. The social reality that was constructed in folklore can be a gap between the real and imaginary condition in the text. This study dug out the interrelatedness between the reflection of folklore as the forming of the resilience nation’s character and characteristic of Indonesian’s diversity. This study uses a qualitative description method and literature sociology and politic approach. The corpus data are “Mentiko Betuah” (Aceh) and “Raja Negeri Jambi” (Jambi) story. The results of the study indicated that the social reflection of both (stories) can be the basis of the building social resilience to counter radicalism, to grows up tolerances, mutual solidarity, democracy, and the integrity of anti-kleptocratic statesman. The method of the study is a qualitative description. The data of the study are sentences and written expressions in “Mentiko Betuah” (Aceh) and “Raja Negeri Jambi”’s story (Jambi). The results of the study indicated that tolerance and plural values were depicted in “Raja Negeri Jambi” and “Mentiko Betuah” were needed to be maintained. The threat of disintegration of the nation through the inculcation of narrow and shallow ideologies have poisoned people’s perspective, especially millennial society.
THE REVIEW OF DISASTER PREPAREDNESS SCHOOL PROGRAM IN INDONESIA ELEMENTARY AND HIGH SCHOOL
Authors: Kurniadi Anwar , Bahar Fauzi
Published: July 2020

Schools are an essential avenue for youth to learn about disaster resilience A critical success factor for the uptake of disaster resilience learning in schools is the ability to embed learning activities in school programs that are linked to relevant curriculums. The introduction of Disaster Preparedness School (DPS) hoped students were able to identify disaster resilience learning and face the disaster occurring. In 2009, the government started developing a pilot project by combining the curriculum disaster education to the curriculum of Disaster Preparedness School (DPS). The purpose of this study was to analyze the cause of inhibition and make a strategy to solve the problem. This study used a literature review approach and source of data search from the literature that obtains via the internet in the form of results of an online library of local, national, and international, and also from books and related regulations. The results of this study are: a) The cause of inhibitions included four indicators like program target inexact, program of socialization less strength,  program goal less power, monitoring program less document incomplete;  b) The strategy to the development program of DPS would be successful under following conditions: 1) insertion curriculum of disaster mitigation education into several subjects, and into extracurricular activities that exist in schools. 2) conducting DPS Program by proper training that has been done by the ways:  right participant, the subject that relates to a local disaster, functional modules, good time setting, monitoring equipment, done routinely and systematically, and also involving the whole stakeholder.
MECHANICAL PROPERTIES ENHANCEMENT OF BORON CARBIDE BASED ARMOUR MATERIALS
Authors: Hartoko Priyadi , Li Sean
Published: July 2020

Lightweight armor materials made from ceramics have become a great interest in the past decades.  There have been many research efforts to develop the high-performance ceramics for this particular application. Boron carbide (B4C) is one of the promised candidates due to its extraordinary hardness, wear resistance, chemical inertness, ultra-lightweight, and its high resistance to radiation.  However, the strong covalent bonding nature of B4C makes it hard to be sintered.  Sintering at high temperatures and the presence of impurities can also result in grain coarsening. One of the methods being used to overcome the problems is to introduce Boron (B) as a sintering aid into raw materials of B4C.  To evaluate the effects of B addition on the sinterability of B4C, B4C powders were ball-milled with B powders in different ratios and the mixtures of B4C and B were processed by spark plasma sintering technique. Density and toughness of the as-sintered materials were increased along with increasing B content in the range from 1 wt% to 7 wt% while hardness and strength of the samples were also increased when the percentage of B addition is up to 5 wt%.
A pilot study of ruxolitinib as a front-line therapy for 12 children with secondary hemophagocytic lymphohistiocytosis
Authors: Qing Zhang  , Ang Wei  , Hong-Hao Ma  , Li Zhang  , Hong-Yun Lian  , Dong Wang  , Yun-Ze Zhao  , Lei Cui  , Wei-Jing Li  , Ying Yang  , Tian-You Wang  , Zhi-Gang Li  , Rui Zhang
Published: July 2020

Hemophagocytic lymphohistiocytosis (HLH) is an immune-regulatory disorder characterized by excessive production of inflammatory cytokines. The treatment recommendations of the HLH-1994 and HLH-2004 protocols have long been used in HLH therapy, but some patients still do not respond well to or have unacceptable side effects from conventional therapies. It is believed that cytokine-targeted strategies that directly target disease-driving pathways will be promising options for HLH. This prospective study aimed to investigate the efficacy and safety of ruxolitinib, a Janus kinase (JAK) 1/2 inhibitor, as a front-line therapy in children with secondary HLH. Twelve newly diagnosed patients without previous treatment were enrolled in this study with a median follow-up of 8.2 (7.1-12.0) months, including 8 cases of Epstein-Barr virus associated HLH (EBV-HLH), 2 cases of autoinflammatory disorder (AID)- associated HLH, and 2 cases of unknown etiology. Patients received oral ruxolitinib dosed on 2.5 mg, 5 mg or 10 mg twice daily depending on the body weight for 28 consecutive days. The overall response rate at the end of treatment (day 28) was 83.3% (10/12), with 66.7% (8/12) in complete response (CR), 8.3% (1/12) in partial response (PR), and 8.3% (1/12) in HLH improvement. Among the patients achieving CR, 87.5% (7/8) maintained CR condition for>6 months, and one patient with EBV-HLH relapsed following CR. For the EBV-HLH subgroup, all 8 patients responded to ruxolitinib, with a CR rate of 75% and a PR rate of 25%. Two patients with AID-associated HLH had quite different responses, with one showing reversal of the HLH abnormalities soon and the other showing no improvement, as did the two cases of unknown etiology. Patients who had no response or discontinued ruxolitinib all responded well to the subsequent HLH-1994 regimen. The expected 6-month event-free survival (EFS) rate was 58.3%±10.2%. No serious adverse effects were reported. Our study provides further support for the possibility of ruxolitinib targeted therapy for secondary HLH in children. This study was registered in the Chinese Clinical Trials Registry Platform (http://www.chictr.org.cn/) as ChiCTR2000029977.
Hematopoietic recovery and immune reconstitution after axicabtagene ciloleucel in patients with large B-cell lymphoma
Authors: Paolo Strati  , Ankur Varma  , Sherry Adkins  , Loretta J. Nastoupil  , Jason Westin  , Fredrick B. Hagemeister  , Nathan H. Fowler  , Hun J. Lee  , Luis E. Fayad  , Felipe Samaniego  , Sairah Ahmed  , Yiming Chen  , Sandra Horowitz  , Sara Arafat  , Swapna Johncy  , Partow Kebriaei  , Victor Eduardo Mulanovich  , Ella Ariza Heredia  , Sattva S. Neelapu
Published: July 2020

Chimeric antigen receptor (CAR) T-cell therapy targeting CD19 may be associated with long-term adverse effects such as cytopenia and immune deficiency. In order to characterize these late events, we analyzed 31 patients with relapsed or refractory large B-cell lymphoma treated with axicabtagene ciloleucel at our institution on two clinical trials, ZUMA-1 (clinicaltrials gov. Identifier: NCT02348216) and ZUMA-9 (clinicaltrials gov. Identifier: NCT03153462). Complete blood counts, lymphocyte subsets, and immunoglobulin levels were measured serially until month 24 or progression. Fifteen (48%) patients had grade 3-4 cytopenia, including anemia (five, 16%), neutropenia (nine, 29%), or thrombocytopenia (13, 42%) at day 30. Cytopenia at day 30 was not significantly associated with later diagnosis of myelodysplasia. Among patients with ongoing remission, grade 3-4 cytopenia was observed in one of nine (11%) at 2 years. While peripheral CD8+ T cells recovered early, CD4+ T-cell recovery was delayed with a count of <200/mL in three of nine (33%) patients at 1 year and two of seven (29%) at 2 years. Immunoglobulin G levels normalized in five of nine (56%) patients at 2 years. Thirteen (42%) patients developed grade 3-4 infectious complications, including herpes zoster and Pneumocystis jiroveci pneumonia. These results suggest the need for prolonged monitoring and prophylaxis against opportunistic infections in these patients, to improve the longterm safety of axicabtagene ciloleucel therapy.
Response to Callus Induction and Regeneration of Newly Released BRRI Rice Varieties
Authors: Joya SD , Sultana S , Ferdous J , Qayum MA , Hoque ME
Published: July 2020

A study was carried out for developing an efficient callus induction and regeneration system for three newly developed BRRI varieties namely BRRI dhan86, BRRI dhan87 and BRRI dhan89. Dehusked seeds were plated onto MS and N6 media with two hormone combinations for callus induction. Calli obtained from each callus induction medium were transferred to four different regeneration media. Callus induction frequency and regeneration ability were significantly influenced by rice varieties, and interactions of variety and media. Among the media compositions, the highest callus (59.44%) were obtained from C1 (MS+2mg/l 2,4-D) followed by C2 ( MS+2 mg/l 2,4-D+0.5 mg/l kinetin) , C3 ( N6+2 mg/l 2,4-D) and C4 (N6+2 mg/l 2,4-D+0.5 mg/l kinetin) medium. The highest regeneration (45.74%) was obtained from R2 (MS+4 mg/ml BAP+1.2 mg/ml kinetin+0.5 mg/ml NAA), followed by R3 (1 mg/ml BAP+1 mg/ml Kinetin+1 mg/ml NAA), R4 (2 mg/ml kinetin+1 mg/ml NAA+300 mg casein hydrolysate) and R1 (2 mg/ml BAP+1 mg/ml kinetin+1 mg/ml NAA). BRRI dhan86 showed the highest regeneration ability (53.06%) than the other two varieties. It is observed that all varieties performed better in C1 medium for callus induction and R2 medium for regeneration. This study also revealed that BRRI dhan86 was more responsive to callus induction and regeneration of green plants than the other two varieties.

Bangladesh Rice j. 2019, 23(2): 17-25
Genetic Variability, Heritability, Correlation and Path Coefficient Studies for Yield and Yield Components of Some Promising Rice Hybrids
Authors: Akter A , Hasan MJ , Latif MA , Kulsum MU , Biswas PL , Rahman MH , Majumder RR , Lipi LF , Quddus MR , Akter F , Ara A
Published: July 2020

Eight promising hybrids along with three checks were evaluated for yield and yield contributing traits to observe their genetic variability, heritability, correlation and path coefficient analysis during T. Aman season 2014. The results indicated that the highest genotypic variance was recorded in spikelet panicle-1 followed by effective tiller m-2. Similarly, the highest phenotypic variances were also found with these two characters. Phenotypic coefficient of variation (PCV) was slightly higher than genotypic coefficient of variation (GCV) for all the traits under this study. Hence, slight differences indicate less or minor environmental influence and greater role of genetic factors on the expression of the traits. High heritability was observed in all the characters studied except effective tiller m-2. Highly significant and positive correlations of grain yield with effective tiller m-2, spikelet panicle-1 at genotypic level were observed. Spikelet fertility was found significant at both genotypic and phenotypic level. Path analysis revealed that spikelet fertility had highly positive direct effect on grain yield followed by effective tiller m-2. On the other hand, spikelet panicle-1 showed positive indirect effect on grain yield. Thus, the results suggested that effective tiller m-2; number of spikelet panicle-1 and spikelet fertility (%) could be considered as effective selection criteria for the development of heterotic rice hybrids.

Bangladesh Rice j. 2019, 23(2): 27-34
Genetic Diversity of Bacterial Blight Resistant Rice (Oryza sativa L.) Genotypes from INGER
Authors: Akter F , Islam MZ , Akter A , Debsharma SK , Shama A , Khatun M
Published: July 2020

Genetic diversity of 65 rice genotypes was studied from IRBBN (International Rice Bacterial Blight Nursery) of INGER (International Network for Genetic Evaluation of Rice) materials through Mahalanobis D2 statistic for grain yield and yield contributing characters. The genotypes were grouped into five clusters. The inter-cluster distances were higher than intra-cluster distances indicating wider genetic diversity among the genotypes of different clusters. The intra-cluster distances were lower in all the cases reflecting homogeneity of the genotypes within the clusters. The cluster III contained the highest number of genotypes (23) and the clusterv contained the lowest (8). The highest intra-cluster distance was noticed for the cluster I and lowest for cluster III. The highest inter-cluster distance was observed between cluster I and V, followed by cluster IV and V, cluster II andV and the lowest between cluster I and IV. Regarding inter-cluster distance, the genotypes of cluster V showed high genetic distance from all other clusters. The genotypes from cluster V could be hybridized with the genotypes of other clusters for producing transgressive segregants. Based on canonical vector analysis, panicle number per plant had maximum contribution towards genetic divergence. The highest cluster means for yield, grain/panicle and spikelet fertility were obtained from cluster V. The highest means for 1000 grain weight, second higher yield and the lowest growth duration were found in cluster II, while the lowest mean value for yield and 1000 grain weight and higher mean value for growth duration were found in cluster IV. The crosses between the genotypes/parents of cluster V and cluster II, cluster V and cluster I would exhibit high heterosis as well as higher level of yield potential. Therefore, more emphasis should be given for selection of the genotypes from clusters II and V for future breeding programme.

Bangladesh Rice j. 2019, 23(2): 59-64
Alteration of serum calcium and magnesium level in transfusion dependent thalassemic patients with combined iron chelator therapy
Authors: Munira Fatema Tuz , Begum Shelina , Urmi SFH
Published: July 2020

Background: Regular blood transfusion and iron chelation is the primary treatment of thalassemia patientsto maintain their life. Iron chelatormay alter serum total calcium and magnesium level in TDT patients.

Objective: To evaluateany alteration of serum total calcium and magnesium level in transfusion dependent thalassemia patients treated with iron chelator.

Method: The present cross sectional study was carried out in the department of Physiology, BSMMU, Dhaka between September 2017 to February 2019. Thirty cases of TDT, aged 5-40 year were included in the study group. Age and sex matched 30 healthy subjects were also studied as control. All the TDT patients were selected from the outpatient Department of Hematology and Transfusion Medicine, BSMMU, Dhaka. Serum total calcium, magnesium and ferritin levels were measured by colorimetric method. For statistical analysis independent sample t test and Chi-Square test and Pearson correlation coefficient test were used.

Result: The mean serum total calcium and magnesium levels were significantly (p<0.05) lower and serum ferritin level was significantly (p<0.001) higher in study group compared to that of control. Again, in this study group 6.7 % TDT patients had hypocalcemia and 13.3% TDT patients had hypomagnecemia.

Conclusion: This study may conclude that low serum total calcium and magnesium level may be associated with TDT patients treated by combined deferoxamine (DFO) & deferiprone (DFP) iron chelator.

J Bangladesh Soc Physiol. 2020, June; 15(1): 17-22
Effect of music therapy on heart rate variability in generalized anxiety disorder: A poincaré analysis
Authors: Mallik Bithi , Ferdousi Sultana , Sultana Shamima
Published: July 2020

Background: Poincare plot analysis of heart rate variability (HRV) is a complex nonlinear method for assessing cardiac autonomic nerve function (CANF) in generalized anxiety disorder (GAD).

Objective: This study aimed to observe the effect of music therapy on HRV by poincaré plot analysis in GAD patients.

Methods: This prospective Interventional study was done in 2019 on 60 newly diagnosed GAD patients aged 20- 40 years, both male and female. Among them, 30 patients were under music therapy with Raga Bhairabi based Rabindra Sangeet for 3 months and 30 patients were without music therapy and both patient groups were studied over three months. Healthy controls, who were enrolled in this study, were Age, sex and BMI matched. Poincaré plot (non linear measure) of HRV of all GAD patients and control were recorded at baseline and after three months of follow up. HRV were recorded by Power Lab 8/ 35. For statistical analysis Bonferroni’s Post Hoc test and paired sample ‘t’ test were done.

Results:Standard deviation of the points perpendicular to the axis of line of identity(SD1), standard deviation of the points along the axis of line of identity (SD2) SD and SD1/SD2 were significantly lower in all GAD patients compared to healthy control at baseline. After 3 months of music therapy, significant increment of these parameters occurred in GAD patients, whereas no changes of these except SD1 were noted in patients without music therapy after 3 months. Moreover, these parameters were not significantly different in patients under music therapy compared to control at the end of three months.

Conclusion: This study concluded that music therapy can improve cardiac autonomic dysfunction in GAD patients.

J Bangladesh Soc Physiol. 2020, June; 15(1): 39-45
Ergonomics-Follow and Keep Well
Authors: Mohammed Emran -
Published: July 2020

Abstract not available

KYAMC Journal Vol. 11, No.-2, July 2020, Page 57-58
EEffect of Great Saphenous Vein Harvesting in Lower Limb Following Coronary Artery Bypass Grafting in Diabetic Patients
Authors: Ahsan Mahbub , Kashem Md Abul , Kibria Md Golam
Published: July 2020

Background: Coronary artery bypass graft Surgery is an established method of myocardial revascularization. Great saphenous vein is the conduit of choice for all cardiac surgeons.

Objective: To compare the effect of great saphenous vein harvesting on lower limb such as swelling, pain, discharge with diabetic and non diabetic CABG patients in whom great saphenous vein was used as a conduit.

Materials and Methods: It was a cross sectional study on 60 patients who underwent CABG during July 2003 to June 2005 in department of cardiovascular surgery, National Institute of Cardiovascular Diseases (NICVD).

Results: The age in group A (Diabetic) ranged from 40-72 years in group B (Non Diabetic) the age range was 40-65 years. Myocardial infarction and Congestive cardiac failure were the predominant risk factors in both age groups. There was no motor or sensory disturbances post operatively. Some patients developed swelling, tenderness, paresthesia in both group but it was not statistically significant.

Conclusion: Morbidity occurs in both diabetic and non diabetic patients with certain complications like numbness, paresthesia, swelling etc. at the harvesting site.

KYAMC Journal Vol. 11, No.-2, July 2020, Page 59-61
Maternal Risk Factors, Clinical Profile and Short-Term Outcome of Pre-Term Low Birth Weight Babies
Authors: Jinnat Mosammat Afroza , Ahmed Shafi , Monira Sirajum , Haque Muhammad Mozammel , Musharraf Mashura , Hasan Md Rabiul
Published: July 2020

Background: Preterm Low Birth Weight babies carry relatively higher risk of perinatal and neonatal mortality, retarded growth and development subsequently. In this study, some maternal risk factors were investigated as it seems to be important to study these factors on regional basis.

Objective: To find out the maternal risk factors, clinical profile and short term outcome of pre-term low birth weight neonates by gestational age, birth weight, Occipitofrontal Circumference, length, different presentation (asphyxia, hypothermia, feeding difficulties, signs of infection) on admission and the morbidity and mortality of preterm LBW.

Materials and Methods: A descriptive type of cross sectional study was done in neonatal ward of Jalalabad Ragib Rabeya Medical College Hospital, Sylhet from May, 2015 to April, 2016. Hundred cases were selected from neonatal ward and 100 controls were selected from obstetrics ward.

Results: Among 100 pre-term LBW neonates, 52 were male and 48 were female. Only 22% mother took regular antenatal check up in case group and 55% in control group. Mean gestational age of neonates were 33.3±2.1 weeks. Important risk factors were primi parity (58% in cases vs 34% in control), hypertension (19% vs 5%), pre-eclampsia (26% vs 12%), prolonged rupture of membrane (33% vs 7%), APH (22% vs 0%), acute infection (8% vs 1%), multiple birth (17% vs 2%). Common clinical presentations were prematurity and LBW. Commonest morbidity was feeding problem (70%). The overall survival rate was 87%. Most common cause of death was septicemia (30%).

Conclusion: all the identified risk factors were significantly higher in pre-term LBW babies than those of control.

KYAMC Journal Vol. 11, No.-2, July 2020, Page 77-82
Solitary Rectal Ulcer Syndrome in a 12-Year Bangladeshi Boy: an Unusual Cause of Rectal Bleeding
Authors: Md Benzamin - , Fathema Kaniz , Saha Dipawnita , Nahar Bodhrun , Akther Sharmin , Nahid Khan Lamia
Published: July 2020

Solitary rectal ulcer syndrome (SRUS) is an uncommon cause of per rectal bleeding in children. Due to it's wide variety of presentation and rarity, it is frequently misdiagnosed as other clinical condition like inflammatory bowel disease, rectal polyp, amoebiasis or malignancy. Here we presenting a case initially misdiagnosed as ulcerative colitis, latter after thorough evaluation diagnosed as a case of SRUS.

KYAMC Journal Vol. 11, No.-2, July 2020, Page 104-107
Faktor-faktor yang Mempengaruhi Kepatuhan Ibu dalam Pemberian Imunisasi Difteri pada Balita
Authors: Muklati Ameylia Hilda , Rokhaidah Rokhaidah
Published: July 2020

Imunisasi merupakan upaya pencegahan untuk meningkatkan kekebalan seseorang terhadap beberapa penyakit yang dapat dicegah dengan imunisasi (PD3I) khususnya imunisasi Difteria Pertusis Tetanus (DPT). Penelitian ini bertujuan untuk menganalisis hubungan karakteristik (usia ibu, pendidikan ibu, pekerjaan ibu), pengetahuan ibu, sikap ibu, kepercayaan ibu dan dukungan keluarga dengan kepatuhan ibu dalam pemberian imunisasi difteri pada balita. Penelitian ini menggunakan analitik kuantitatif dengan desain Cross-Sectional. Pengambilan sampel menggunakan teknik purposive sampling sehingga didapatkan sampel 75 responden. Responden penelitian adalah ibu yang memiliki balita (usia 1-5 tahun) di RW 01 Kelurahan Kukusan Kecamatan Beji Kota Depok. Instrumen yang digunakan adalah data primer (kuisioner dan observasi) dan data sekunder (buku KMS/KIA). Analisis data yang digunakan yaitu uji statistik bivariat dengan uji Chi-Square. Hasil penelitian terdapat hubungan yang bermakna antara usia ibu (p=0,008), tingkat pendidikan ibu (p=0,000), status pekerjaan ibu (p=0,003), tingkat pengetahuan ibu (p=0,001), sikap ibu (p=0,001), kepercayaan ibu (p=0,003) dan dukungan keluarga (p=0,000) dengan kepatuhan ibu dalam pemberian imunisasi difteri pada balita di RW 01 Kelurahan Kukusan Kecamatan Beji Kota Depok. Peneliti merekomendasikan pendidikan kesehatan tentang imunisasi kepada ibu untuk meningkatkan kepatuhan dalam pemberian imunisasi pada anak.
Hubungan Lamanya Penggunaan Alat Kontrasepsi Hormonal Suntik Tiga Bulan dengan Hipertensi
Authors: Fatmawati Ariani , Mulyani Mulyani , Lusiani Eli
Published: July 2020

Alat kontrasepsi hormonal paling banyak diminati, sebagian besar peserta menggunakan kontrasepsi hormonal KB suntik tiga bulan. Penelitian ini bertujuan untuk mengetahui hubungan lamanya penggunaan alat kontrasepsi hormonal KB suntik tiga bulan dengan kejadian hipertensi di wilayah kerja UPT Puskesmas Kopo Kota Bandung. Jenis penelitian ini adalah penelitian kuantitatif dengan pendekatan cross sectional. Populasi dalam penelitian ini adalah seluruh ibu yang menggunakan KB suntik tiga bulan diwilayah kerja UPT Puskesmas Kopo sebanyak 741 orang. Teknik sampling yang digunakan adalah accidental sampling dengan total sampel sebanyak 101 responden. Pengambilan data dilakukan secara langsung menggunakan lembar data demografi dan dilakukan pengukuran tekanan darah sesuai dengan prosedur penelitian. Waktu penelitian dilakukan pada bulan November – Desember 2019. Analisis yang digunakan adalah uji statistik Chi-Square. Hasil penelitian menunjukan bahwa terdapat hubungan antara lamanya penggunaan kontrasepsi hormonal KB suntik tiga bulan dengan kejadian hipertensi (p=0,000). Saran penelitian, memberikan penyuluhan kepada akseptor KB suntik tiga bulan yang lebih dari 5 tahun untuk beralih ke alat kontrasepsi non hormonal. Hal ini dimaksudkan untuk menstabilkan kadar hormone dalam tubuh.
AN OVERVIEW OF TIME-DOMAIN COMPUTATIONAL METHODS FOR AEROELASTIC INSTABILITIES OF MULTI-STAGE COMPRESSOR
Authors: Vahdati Mehdi , Zhao Fanzhou , Sureshkumar Prathiban
Published: July 2020

Modern gas turbine design continues to move towards improved performance, reduced weight and reduced cost. As turbomachinery blade aerofoils are thinned to improve performance and reduce weight, aeroelastic issues such as flutter, forced response and stall driven vibrations become more predominant. Moreover, as the use of blisks (blade-integrated-disks) with very low mechanical damping becomes more common in modern compressor designs, accurate prediction of compressor aeroelastic stability in a multi-row environment becomes vital. This paper presents a review of aeroelasticity research carried out at Rolls-Royce Vibration University Technology Centre (VUTC) at Imperial College over the past 20 years. The aim is to summarise the unusual aeroelastic issues observed in multi-stage compressors into one document so that it can be used by other researchers in the field. Blade passing forced response is not addressed here as their existence can be detected by a Campbell diagram. The results presented here are based on numerical methods but where possible data from experiments are used to verify the numerical findings.
Hydroxysafflor Yellow A Protects Against Myocardial Ischemia/Reperfusion Injury via Suppressing NLRP3 Inflammasome and Activating Autophagy
Authors: Ye Jingxue , Lu Shan , Wang Min , Ge Wenxiu , Liu Haitao , Qi Yaodong , Fu Jianhua , Zhang Qiong , Zhang Bengang , Sun Guibo , Sun Xiaobo
Published: July 2020

Myocardial ischemia/reperfusion (MI/R) injury is a serious threat to human health. Hydroxysafflor yellow A (HSYA), the main water-soluble ingredient extracted from Carthami flos (Carthamus tinctorius L.), has therapeutic potential for treating MI/R injury. However, the mechanisms of HSYA−mediated protection from MI/R injury are incompletely understood. In the present study, we investigated the effects and the underlying mechanisms of HSYA during MI/R. Adult Sprague-Dawley rats were subjected to left anterior descending artery ligation for 30 min followed by 24 h of reperfusion with or without HSYA treatment. The protective effect of HSYA was detected by 2,3,5-triphenyl tetrazolium chloride (TTC) staining, hematoxylin eosin (HE) staining, and myocardial enzymes detections. Serum levels of inflammatory factors such as TNF-α, interleukin (IL)-1β, and IL-18, were detected using ELISA kits. The expression of NLRP3 and other related proteins in the myocardium was detected by western blot and immunohistochemistry. The expression of autophagy-related proteins, including Atg5, BECN1, P62, and LC3B, was detected by western blot to evaluate the effect of HSYA on autophagy. Results showed that HSYA decreased the myocardial infarct size and attenuated the cardiac dysfunction in rats after I/R. In addition, HSYA inhibited myocardial apoptosis compared with the I/R group, decreased the levels of inflammatory cytokines in rat serum, reduced NLRP3 inflammasome expression, and induced autophagy. Mechanistically, our results demonstrated that HSYA can activate AMPK to improve autophagy and inhibit NLRP3 inflammasome by inhibiting the mTOR pathway. This work provides strong data supporting for the clinical applications of HSYA in MI/R injury.
Effects of Biochar and Ground Magnesium Limestone Application, with or without Bio-Fertilizer Addition, on Biochemical Properties of an Acid Sulfate Soil and Rice Yield
Authors: Panhwar Qurban Ali , Naher Umme Aminun , Shamshuddin Jusop , Ismail Mohd Razi
Published: July 2020

A study was conducted to evaluate the effects of applying rice husk biochar (RHB) or ground magnesium limestone (GML) in combination with bio-fertilizer on soil biochemical properties and the yield of rice planted on an acid sulfate soil. The RHB or GML plus bio-fertilizer were applied each at the rate of 4 t ha−1. Applying the amendments increased soil pH (>5.0) and improved soil biochemical properties with a concomitant reduction of Al and Fe that resulted in enhanced rice growth. Applying GML plus bio-fertilizer resulted in increased soil N content (0.20%), available P (34.38 mg kg−1), exchangeable Ca (2.97 cmolc kg−1) and exchangeable Mg (2.45 cmolc kg−1); all these enhanced rice nutrient uptake. The highest bacterial population of 8.34 log10 CFU g−1 soil was found in the same treatment. Applying GML and RHB alone, or in combination with bio-fertilizer, was found to enhance rice growth and the yield. The highest plant height (90.33 cm), leaf chlorophyll content (38.05), plant tiller numbers (16), filled grains (86%), number of panicles per plant (18), lengths of panicles (24.40 cm), grain (5.24 t ha−1), straw yield (10.20 t ha−1) and harvest index (0.51) were determined in the GML plus bio-fertilizer, followed by RHB plus bio-fertilizer treatment. Thus, GML applied in combination with bio-fertilizer is considered as a promising agronomic package to sustain the production of rice planted on acid sulfate soils.
Potassium Fertilisation Is Required to Sustain Cassava Yield and Soil Fertility
Authors: Chua Ming Fung , Youbee Laothao , Oudthachit Saythong , Khanthavong Phanthasin , Veneklaas Erik J. , Malik Al Imran
Published: July 2020

Cassava is often grown in low-fertility soils and has a reputation for having modest nutrient requirements. The storage roots that are harvested, however, contain relatively large amounts of potassium (K). We carried out a field experiment in Laos to determine the growth response to K fertiliser and to examine the field’s K balance over the cropping season. Four different rates of K (0-40-80-120 kg K2O equivalents ha−1) were applied to cassava variety Rayong11. Harvests were done at 8 and 10 months after planting, when the crop was at early and full maturity respectively, to assess if any benefits for productivity or K balance could be achieved by early harvest. We found a positive effect of K fertiliser (up to 39% yield increase compared to no K fertiliser at early harvest, 21% at late harvest) and a positive effect of late harvest (on average a 35% increase compared to early harvest) on cassava root yield. Low-K crops benefited more from a late harvest. At 10 months, the harvested cassava contained 99–142 kg K ha−1, indicating that there was a net removal of K from the fields, even at high K fertilisation levels. This experiment was carried out in comparatively fertile soil with relatively high background K levels, yet, yield benefits of K fertilisation were observed and soil K reserves were depleted by the harvest. It can be concluded that K fertilisation of cassava is advisable for better yields and to avoid progressive depletion of the soil K capital.
Characterization of Different Commercial Dietary Supplements in the Peri-Weaning Period on Consumption and Growth Performance in C57Bl/6J Mice
Authors: Craig Angela M. , Graham Melanie L.
Published: July 2020

This experiment was conducted to investigate the effects of common commercially available dietary supplementation in the peri-weaning period on feed intake, growth, and survival in C57Bl/6J mouse pups and lactating dams. A total of 96 pups and their dams were randomized to the control group or one of three nutritional supplement treatment groups: (i) control group without supplementation, or (ii) weanling-targeted Clear H2O gel (Gel), (iii) transgenic-targeted Bio-Serv dough (Dough), or (iv) dam diet as a mash (Chow), in the peri-weaning period (from 11 to 28 days). Stool was observed daily for a dye marker indicating supplement consumption. Pups were weaned at 21 days and followed for a total of 42 days. No pup morbidity or mortality was observed. There was a higher proportion of pups consuming dough and gel earlier than chow (p = 0.0091). The majority of treated pups (>95%) were consuming the supplement by day 23 (range 15–23), suggesting interplay between organoleptic properties of the supplement and pup maturity. All groups gained weight, with typical sexual dimorphism observed in the growth curves. Dough treatment led to significantly higher average daily gain in male pups (0.64 ± 0.03 g/d) as compared with controls (0.58 ± 0.03 g/d). The highest average daily gain in all groups was observed pre-weaning between days 21 and 28. Compared with controls, the weight gain slope was significantly higher in the Dough and Chow treatment groups and lower in Gel treatment groups, with a more pronounced effect in males. In this study, the composition of nutritional supplementation was the dominant factor in increasing the growth trend as opposed to energy density. Peri-weaning supplementation with Dough and Chow treatments improved pre- and post-growth performance in a comparable way and was more effective than Gel treatment during adaptation to solid feeding. Proper application of supplements to support weanlings can directly improve welfare and limit unintended experimental variability.
Intra-Group Lethal Gang Aggression in Domestic Pigs (Sus scrofa domesticus)
Authors: Camerlink Irene , Chou Jen-Yun , Turner Simon P.
Published: July 2020

Intraspecific coalitional aggression is rare among all species, especially within stable social groups. We report here numerous cases of intraspecific lethal gang aggression within stable groups of domestic pigs. The objective was to describe this extreme aggression and to identify potential causes. Management data were collected from farms with (n = 23) and without (n = 19) gang aggression. From one farm, 91 victims were assessed for skin injuries and body condition score. Lethal gang aggression was significantly associated with deep straw bedding, which may be related to various other factors. Gang aggression tended to occur more in winter, and was unrelated to genetic line, breeding company, group size or feed type. It occurred equally in female-only and mixed sex groups (male-only groups were not represented), from around eight weeks of age. Injuries typically covered the whole body and were more severe on the front of the body. Victims who survived had a lower body condition score and fewer injuries than victims found dead. There are still many unknowns as to why this abnormal social behaviour occurs and it deserves further research attention, both for its applied relevance to animal welfare as for the evolutionary background of lethal gang aggression.
Milk Production, N Partitioning, and Methane Emissions in Dairy Cows Grazing Mixed or Spatially Separated Simple and Diverse Pastures
Authors: Carmona-Flores Lorena , Bionaz Massimo , Downing Troy , Sahin Muhammet , Cheng Long , Ates Serkan
Published: July 2020

Increasing pasture diversity and spatially separated sowing arrangements can potentially increase the dry matter intake of high-quality forages leading to improved animal production. This study investigated the effects of simple (two-species) and diverse (six-species) pastures planted either in mixed or spatially separated adjacent pasture strips on performance, N partitioning, and methane emission of dairy cows. Thirty-six mid-lactation Jersey cows grazed either (1) simple mixed, (2) simple spatially separated, (3) diverse mixed, or (4) diverse spatially separated pastures planted in a complete randomized block design with three replicates. Compared to simple pasture, diverse pasture had lower CP content but higher condensed tannins and total phenolic compounds with an overall positive effect on yield of milk solids, nitrogen utilization, including a reduction of N output from urine, and methane yields per dry matter eaten. The spatial separation increased legume and CP content in simple pasture but decreased NDF in both diverse and simple pastures. In conclusion, increasing diversity using pasture species with higher nutritive value and secondary compounds can help improving the production while decreasing the environmental effect of dairy farming, while spatial separation had a minor effect on feed intake and yield, possibly due to overall high-quality pastures in early spring.