bluuebunny/crossref_metadata_2025 huggingface dataset:
Knowledge, Attitudes and Practices Regarding Dengue, Chikungunya, and Zika and their Vector Aedes Aegypti in Villavicencio, Colombia
Authors: Jaramillo Ramírez Gloria I. , Álvarez Luz S. Buitrago
Published: June 2017

Background:

Aedes aegyptitransmits dengue, chikungunya and zika, and high infestation rates of this mosquito are responsible for maintaining these arbovirus outbreaks in endemic areas

Objective:

To estimate the knowledge, attitudes, and practices regarding dengue, chikungunya, and zika and their vectorAedes aegyptiin Villavicencio, Colombia.

Methods:

A descriptive, cross-sectional study was conducted. Verbal informed consent was obtained from adults and then interviewed using a structured questionnaire. Houses were randomly selected; in the event that no one was home, the next house was selected. Entomological data were recorded to calculate the larval indexes at homes.

Results:

Seventy-six houses (309 people) were evaluated. 70% of subjects were aware that dengue, chikungunya or zika are viral diseases. Fever was considered the most important symptom and could be related to the experience of having these diseases at home. 79.45% knew that a mosquito transmits these diseases but did not know the scientific name or that only the female bites. 81.36% did not know the life cycle of the mosquito but were aware that the elimination of breeding sites and destruction of containers with water could aid in transmission prevention. 88.46% recognized that the community should be responsible for these control actions at home, but the recommendations are not implemented due to the lack of interest or apathy. The average house index was 40.3%, and Breteau index was 47.66%. Low tanks represented the most common breeding site.

Conclusion:

It is necessary to review campaigns, communication, and education promoted in the municipality because they do not reflect the knowledge of the people.
Engaging in Enhancement: Implications of Participatory Approaches in Higher Education Quality Assurance
Authors: Groen Jovan F
Published: June 2017

Stemming from increased levels of participation and diversity of the student base and from growing scrutiny on the quality of university degrees, governments have begun establishing mechanisms to monitor and support quality in higher education. Faced with administrative quality assurance structures, academics often complain that little is discussed in terms of collaborative effort toward program opportunities, enhancement, and growth and that focus is solely on accountability. This paper examines the viability of participatory approaches, pulled from the field of evaluation, as a way of leading to a more meaningful enhancement-oriented quality assurance process and creating common ground across the differing interests of external and internal stakeholders to quality in higher education.
Levers for Change in Educational Development in Canada: Looking Back, Looking Forward
Authors: Dawson Debra Louise
Published: June 2017

This paper examines levers or drivers that have influenced the direction of educational development in Canada over the last 40 years and also tries to predict what will be the impact of some current levers on changing the work of developers in the next 20 years. Reflecting on those years, it is apparent our work in the 1980s was very focussed on the individual and gradually shifted to become more organizational and sector focussed, particularly as the work of developers moved from the periphery to the center of our institutions. The challenge of the next 20 years will be responding to the breadth of areas we are being drawn into in the academy yet, the diversity of our work is one of the strengths of our profession.
Student Motivation in Response to Problem-based Learning
Authors: Fukuzawa Sherry , Boyd Cleo , Cahn Joel
Published: June 2017

Problem-based learning (PBL) is a self-directed learning strategy where students work collaboratively in small groups to investigate open-ended relatable case scenarios. Students develop transferable skills that can be applied across disciplines, such as collaboration, problem-solving and critical thinking.  Despite the extensive research on problem-based learning, an examination of variables that affect student engagement through the implementation of PBL is lacking (Savin-Baden, 2014; 2016).  Our research question examined student motivation during problem-based learning implementation in an undergraduate anthropology course (N = 49) with students with diverse subject matter experience and no previous exposure to active learning.  Student motivation was examined through surveys, peer-evaluations, and self-reflection exercises.  The results showed that student motivation was higher in students with more subject matter experience at the beginning of the course. During the course, motivation decreased in relation to subject matter experience, but by the end of the course the majority of students (76.7%) increased their motivation toward problem-based learning.  Based on their subject matter experience, we were surprised that a particular subset of students had low motivation at the end of the course (78%). We discuss some challenges of implementing problem-based learning in a traditional curriculum, and provide suggestions to successfully implement PBL for diverse student populations.
The Collaborative Case: From Class Assignment to Publication
Authors: Sharen Colleen , Feltham Mark , Braecker Michelle
Published: June 2017

This essay summarizes the experience of a business professor, her student, and an English professor in a collaborative project that resulted in a conference presentation that was subsequently submitted for publication.  We discuss the process of writing a business case, our learning experiences, and some suggestions for practice when undertaking a professor-undergraduate student project with an eye to publication.
Others and Imagination in Reasoning and Argumentation: Improving our Critical Creative Capacity
Authors: Baumtrog Michael D.
Published: June 2017

Contemporary argumentation theories highlight the importance of Others for contributing to and critiquing an individual’s reasoning and/or argumentation. Reasoners and arguers are encouraged to interact with imagined constructs such as a community of model interlocutors or universal audience. These model interlocutors are theoretically meant to bring to mind reasons and counter-considerations that may not have been conceived of otherwise so as to improve the overall quality of an instance of reasoning or argumentation. Overlooked, however, is the impact of differing individual’s imaginative abilities. This paper argues that more important than relying on an Other, real or imagined, reasoners and arguers would do just as well to improve their own creative abilities first. Consulting a real or imagined Other may help in some cases help, but such a strong reliance on Others comes with serious limitations.
HISTORICIZING THE ENCOUNTER BETWEEN STATE, CORPORATE, AND INDIGENOUS AUTHORITIES ON GITXSAN LANDS
Authors: McCreary Tyler
Published: June 2017

This essay charts the shifting assemblage of the conduct of state, corporate, and Indigenous authority through four historical moments: mercantilism, settler colonialism, Indigenous resurgence, and corporate reconciliation. With reference to Gitxsan territories, it makes a series of interrelated arguments. The development of colonial territorial claims and regimes of governance overlapped pre-existent and ongoing Indigenous territorial relationships. The historical division between the political and economic domain reshaped the relationship between state and corporate authorities, the state deferring to corporate actors to manage relations in the economic domain. The conduct of state and corporate authorities has constrained and modified the exercise of Indigenous jurisdiction. Nevertheless, Indigenous resurgence has opened space for renegotiating the colonial legal order, including relations between extractive resource companies and Indigenous authorities. Emergent corporate practices of contracting with Indigenous authorities over development, however, reflect a reconfiguration rather than rupture of the settler colonial legal order. Corporate-Indigenous agreements rely upon colonial modes of organizing lawful political and economic conduct, and continue to block more radical and anti-colonial expressions of Indigenous jurisdiction. To expand possibilities for articulating forms of Indigenous jurisdiction that refuse the categories of colonial political economy, it is necessary to problematize the relationship between colonial state and corporate authority.
Untitled: Women's Work
Authors: Adesola Akinleye
Published: June 2017

Untitled: Women’s Work is both scholarly art and artistic research using narrative inquiry, dance and film as research methods. The research looks at the embodied experience of a group of women in the work place. Methodology for this research was to use an embodied approach across the whole research process from dancing with participants as part of the date collection process, to using choreographic tasks to analyze the data and finally using dance and film to disseminate the ‘findings’.

The research looked at the lived experience of women living and working in the Flint and Detroit areas, USA. It is an attempt to take the body and bodily experiences ‘seriously’ when we research. The research took the position that embodiment is a methodology and method for understanding the narratives of the women’s work and what makes a ‘good’ job. I saw dance and visual images as a language for communication of the ideas the research uncovered.

Data collection asked women participants what they considered makes a good job along with collecting their memories of their own working experiences (this was done through dancing together and verbal interviews). Analysis drew out two themes: relationships (developed and negotiated in the situation of work and Self), and rhythms (of Self and work institution). Initial findings presented here suggest the continual establishment, disruption, negotiation and maintenance of rhythms and relationships in the work place has an impact on what makes a ‘good’ job.

The research is part of my on-going study of how an embodied approach to the lived experience (based of Pragmatist and Phenomenological principles that place bodily experience as central to meaning making) can be embedded into the whole research process. This challenges ‘traditional’ research methods, that it could be argued, place the body as an add-on to text-based theory even when the research subject it self is about people's experiences.
Determinación experimental del módulo de compresibilidad adiabático para aceites minerales
Authors: Prado Martinez William , Hoyos Mesa Mario
Published: June 2017

En este trabajo se propone un método y se diseña un equipo para la determinación experimental del módulo de compresibilidad adiabático como función de la presión y temperatura en aceites minerales utilizando ondas ultrasónicas. El módulo de compresibilidad adiabático se obtiene al multiplicar el cuadrado de la velocidad de propagación del sonido en el fluido por su densidad.
Diseño e instrumentación de una línea de aire comprimido para un laboratorio académico
Authors: Nieto Vergara Gustavo , Manjarres Sierra Kevis , Galvis Villero Jesus , Rios Bertel Manuel , Roldán Mckinley Javier , Duque Jovanny Rafael
Published: June 2017

Se presentan los pasos a seguir para el diseño de una línea de suministro de aire comprimido para un laboratorio de enseñanza. La normativa aplicada permite la evaluación del tipo de riesgo y su respectiva cuantificación del nivel, asociada al riesgo de sordera profesional por el ruido producido por el compresor. Mediante una matriz de evaluación se consideraron cuatro alternativas de diseño, teniendo en cuenta sugerencias de potenciales usuarios y proveedores del servicio de instalación. Se construyó un DAQ para el monitoreo de la presión en la línea con un transductor piezoeléctrico y un microcontrolador Arduino. La curva del sensor obtenida permite el uso del sistema en futuros proyectos académicos.
Análisis de la Logística Hospitalaria aplicada en las Entidades de Salud de Nivel 3 y 4 en la ciudad de Barranquilla
Authors: Figueroa Geraldino Lindsay Ivania , Wilches Arango Maria Jimena , Romero Daniel , Aguirre Silebis
Published: June 2017

Este artículo presenta una metodología de tipo exploratoria descriptiva basada en el análisis de la logística hospitalaria desde sus diferentes características para las clínicas, IPS y hospitales de nivel 3 y 4 de la ciudad de Barranquilla. Este análisis profundiza sobre las áreas en la que se han aplicado herramientas de logística para el manejo de recursos. La principal debilidad encontrada en este sector es el manejo de inventarios debido a múltiples dificultades sobre abastecimiento y optimización de los niveles adecuados para el funcionamiento eficiente. Es por ello, que a través de esta investigación se establece la situación actual de las entidades de la ciudad de Barranquilla con el fin de proponer recomendaciones que le permitan al sector salud mejorar las condiciones presentes. En esta investigación se aplicó una encuesta a entidades de salud a partir de la cual se obtuvo como resultado que al momento de implementar una herramienta logística existen limitantes financieras, físicas y tecnológicas.  Además se identificó que el manejo y control de inventarios es la herramienta logística que más se ha implementado, aun cuando las entidades consideran que aún se debe ser reforzada.
Técnicas de umbralización para el procesamiento digital de imágenes de GEM-Foils
Authors: Triana Nayid , Jaramillo Andrés E. , Gutiérrez Rafael M. , Rodríguez César A.
Published: June 2017

Una GEM-Foil (Gas Electron Multiplier - Foil) es un componente básico de nuevos detectores de radiación usados principalmente en experimentos de física de altas energías y física nuclear. El desempeño óptimo de tales detectores depende críticamente de la calidad de fabricación de dicho componente, ya que cualquier irregularidad en una de las cientos de miles de micro-perforaciones de la placa puede inducir una chispa durante el funcionamiento y dañar el detector. Actualmente, para evaluar la calidad de fabricación de una GEM-Foil se adquieren imágenes de alta resolución mediante sistemas ópticos que las digitalizan para ser luego examinadas por inspección visual. En este trabajo se comparan varias técnicas para realizar la binarización de las imágenes de las GEM-Foils, aplicando técnicas de umbralización global y local, con el propósito de mejorar la rapidez y eficiencia del procesamiento  de las imágenes de las GEM-Foils para realizar posteriormente su control de calidad. A partir de las pruebas realizadas se encontró que mediante cálculos  estadísticos simples, como el promedio del máximo y mínimo de intensidad, aplicando umbralización local adaptativa es posible realizar la segmentación de las imágenes de una manera eficiente sin tener que recurrir a métodos más complejos los cuales pueden implicar tiempos de proceso demasiado grandes.
Determinación teórica y comparación con datos experimentales de la cantidad de agua producida por una celda de combustible de membrana de intercambio protónico
Authors: Trejos Valencia Jorge Mario , Tibaquirá Giraldo Juan Esteban
Published: June 2017

Este artículo resume el diseño, construcción y simulación de una celda de combustible de membrana de intercambio protónico (CCMIP), así como la validación de los resultados teóricos obtenidos frente a resultados experimentales relacionados con la cantidad de agua producida por ésta. Con las simulaciones se pudo visualizar el comportamiento de la celda de combustible bajo diferentes condiciones de operación. Una vez obtenida la celda de combustible físicamente, se procedió a efectuar mediciones de voltaje generado y corriente que circula por la celda. Dado que los resultados experimentales relacionados con la producción de agua no difieren mucho de los resultados teóricos, puede afirmarse que el trabajo desarrollado con esta celda de combustible constituye un aporte en el área del diseño y construcción de este tipo de dispositivos, sentándose las bases para futuros proyectos relacionados con CCMIP.
Indirect Regulation of Endogenous Glucose Production by Insulin: The Single Gateway Hypothesis Revisited
Authors: Bergman Richard N. , Iyer Malini S.
Published: June 2017

On the basis of studies that investigated the intraportal versus systemic insulin infusion and transendothelial transport of insulin, we proposed the “single gateway hypothesis,” which supposes an indirect regulation of hepatic glucose production by insulin; the rate-limiting transport of insulin across the adipose tissue capillaries is responsible for the slow suppression of free fatty acids (FFAs), which in turn is responsible for delayed suppression of hepatic endogenous glucose production (EGP) during insulin infusion. Preventing the fall in plasma FFAs during insulin infusion either by administering intralipids or by inhibiting adipose tissue lipolysis led to failure in EGP suppression, thus supporting our hypothesis. More recently, mice lacking hepatic Foxo1 in addition to Akt1 and Akt2 (L-AktFoxo1TKO), all required for insulin signaling, surprisingly showed normal glycemia. Inhibiting the fall of plasma FFAs in these mice prevented the suppression of EGP during a clamp, reaffirming that the site of insulin action to control EGP is extrahepatic. Measuring whole-body turnover rates of glucose and FFAs in L-AktFoxo1TKO mice also confirmed that hepatic EGP was regulated by insulin-mediated control of FFAs. The knockout mouse model in combination with sophisticated molecular techniques confirmed our physiological findings and the single gateway hypothesis.
Islet Encapsulation: Physiological Possibilities and Limitations
Authors: Korsgren Olle
Published: June 2017

A logical cure for type 1 diabetes (T1D) involves replacing the lost insulin-producing cells with new ones, preferably cells from a well-characterized and unlimited source of human insulin-producing cells. This straightforward and simple solution to provide a cure for T1D is immensely attractive but entails at least two inherent and thus far unresolved hurdles: 1) provision of an unlimited source of functional human insulin-producing cells and 2) prevention of rejection without the side effects of systemic immunosuppression. Generation of transplantable insulin-producing cells from human embryonic stem cells or induced pluripotent stem cells is at present close to reality, and we are currently awaiting the first clinical studies. Focus is now directed to foster development of novel means to control the immune system to enable large-scale clinical application. Encapsulation introduces a physical barrier that prevents access of immune cells to the transplanted cells but also hinders blood vessel ingrowth. Therefore, oxygen, nutrient, and hormonal passage over the encapsulation membrane is solely dependent on diffusion over the immune barrier, contributing to delays in glucose sensing and insulin secretion kinetics. This Perspective focuses on the physiological possibilities and limitations of an encapsulation strategy to establish near-normoglycemia in subjects with T1D, assuming that glucose-responsive insulin-producing cells are available for transplantation.
Impact of Glycemic Variability on Chromatin Remodeling, Oxidative Stress, and Endothelial Dysfunction in Patients With Type 2 Diabetes and With Target HbA1c Levels
Authors: Costantino Sarah , Paneni Francesco , Battista Rodolfo , Castello Lorenzo , Capretti Giuliana , Chiandotto Sergio , Tanese Luigi , Russo Giulio , Pitocco Dario , Lanza Gaetano A. , Volpe Massimo , Lüscher Thomas F. , Cosentino Francesco
Published: June 2017

Intensive glycemic control (IGC) targeting HbA1c fails to show an unequivocal reduction of macrovascular complications in type 2 diabetes (T2D); however, the underlying mechanisms remain elusive. Epigenetic changes are emerging as important mediators of cardiovascular damage and may play a role in this setting. This study investigated whether epigenetic regulation of the adaptor protein p66Shc, a key driver of mitochondrial oxidative stress, contributes to persistent vascular dysfunction in patients with T2D despite IGC. Thirty-nine patients with uncontrolled T2D (HbA1c >7.5%) and 24 age- and sex-matched healthy control subjects were consecutively enrolled. IGC was implemented for 6 months in patients with T2D to achieve a target HbA1c of ≤7.0%. Brachial artery flow-mediated dilation (FMD), urinary 8-isoprostaglandin F2α (8-isoPGF2α), and epigenetic regulation of p66Shc were assessed at baseline and follow-up. Continuous glucose monitoring was performed to determine the mean amplitude of glycemic excursion (MAGE) and postprandial incremental area under the curve (AUCpp). At baseline, patients with T2D showed impaired FMD, increased urinary 8-isoPGF2α, and p66Shc upregulation in circulating monocytes compared with control subjects. FMD, 8-isoPGF2α, and p66Shc expression were not affected by IGC. DNA hypomethylation and histone 3 acetylation were found on the p66Shc promoter of patients with T2D, and IGC did not change such adverse epigenetic remodeling. Persistent downregulation of methyltransferase DNMT3b and deacetylase SIRT1 may explain the observed p66Shc-related epigenetic changes. MAGE and AUCpp but not HbA1c were independently associated with the altered epigenetic profile on the p66Shc promoter. Hence, glucose fluctuations contribute to chromatin remodeling and may explain persistent vascular dysfunction in patients with T2D with target HbA1c levels.
Maternal BMI and Glycemia Impact the Fetal Metabolome
Authors: Lowe William L. , Bain James R. , Nodzenski Michael , Reisetter Anna C. , Muehlbauer Michael J. , Stevens Robert D. , Ilkayeva Olga R. , Lowe Lynn P. , Metzger Boyd E. , Newgard Christopher B. , Scholtens Denise M.
Published: June 2017

OBJECTIVE

We used targeted metabolomics to determine associations of maternal BMI and glucose levels with cord blood metabolites and associations of cord blood metabolites with newborn birth weight and adiposity in mother-offspring dyads.

RESEARCH DESIGN AND METHODS

Targeted metabolomic assays were performed on cord blood plasma samples from European ancestry, Afro-Caribbean, Thai, and Mexican American newborns (400 from each ancestry group) whose mothers participated in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study and who had anthropometric measurements at birth.

RESULTS

Meta-analysis across the four cohorts demonstrated significant correlation of all cord blood metabolites analyzed with maternal fasting levels of the same metabolites at ∼28 weeks’ gestation except for triglycerides, asparagine/aspartate, arginine, and the acylcarnitine C14-OH/C12-DC. Meta-analyses also demonstrated that maternal BMI with or without adjustment for maternal glucose was associated with cord blood metabolites including the branched-chain amino acids and their metabolites as well as phenylalanine. One-hour but not fasting glucose was associated with cord blood 3-hydroxybutyrate and its carnitine ester, a medium-chain acylcarnitine, and glycerol. A number of cord blood metabolites were associated with newborn birth weight and sum of skinfolds, including a negative association of triglycerides and positive association of 3-hydroxybutyrate, its carnitine ester, and serine with both newborn outcomes.

CONCLUSIONS

Maternal BMI and glycemia are associated with different components of the newborn metabolome, consistent with their independent effects on newborn size at birth. Maternal BMI is associated with a newborn metabolic signature characteristic of insulin resistance and risk of type 2 diabetes in adults.
Direct metal deposition of abrasive tracks—Potentials concerning geometry and materials
Authors: Rommel Daniel , Terock Michael , Scherm Florian , Kuttner Christian , Glatzel Uwe
Published: June 2017

Diamond tools are essential in various industries. The high hardness of diamond enables the machining of a wide range of different materials. The materials processed with diamond cutting tools vary from ceramic or metal components to natural materials like stone. In most cases, the abrasive diamonds of such cutting tools are embedded in a metal matrix. Depending on the application, this metal matrix has to fulfill certain requirements of wear resistance in order to achieve a sufficient tool life in combination with optimal cutting results. Laser cladding offers the opportunity to produce metal bond diamond tools with different matrix materials. In this process, the matrix is applied as metal powder. Together with the diamond particles, the metal powder is blown into the focus of the laser beam. By moving the laser over the workpiece, an abrasive line trace, consisting of diamonds embedded in a metal matrix, is built. In this way, arbitrary geometries (only limited by the handling system) can be generated. For example, dot patterns or spiral tracks can easily be processed. The use of an Yb-fiber laser with high beam quality (1.05 mm mrad) enables us to build up structures with dimensions less than 1 mm. In contrast to our process, the established ways of manufacturing (electroplating or brazing) require huge efforts to produce abrasive coatings with complex shapes. In order to rate the potential of this laser cladding method, especially for small structures, 1 mm and below, the ability and the influence of different matrix materials are of great interest. Therefore, this work examines the evaluation of three different matrix materials: Co-based matrix, Fe-based matrix, and Ti-based matrix. The abrasive clads were analyzed by light optical microscopy and scanning electron microscopy (SEM); in some cases, preparation took place by focused ion beam etching. Moreover, the diamonds were chemically leached out of the metal matrix and analyzed by SEM and Raman microscopy in order to understand the interfacial reactions between the diamond and the matrix melt. The diamond strength, after the laser cladding process, was measured by mechanical tests.
ENTRE IDÉAL, ÉTHIQUE ET LOI: L’ÉQUITÉ
Authors: SARFATI Jean-Jacques
Published: June 2017

Equity between Ideal, Ethics and Law. The purpose of this text is to show that equity is now a need for our post-modernity. However, it can only become a reality only if it is applied by an elite that regains the support of the people and of the intellectual sphere. Without this support and reality, the legal philosophy seeks to build it without being able to convince completely. Indeed, equity cannot be only an idea - it must be a concrete reality and at work. Otherwise, it vanishes.
Zsarnay Lajos teológiája
Authors: BÁTORINÉ MISÁK Marianna
Published: June 2017

The Theology of Lajos Zsarnay.
Zsarnay’s theological thinking was eclectic. Even though he considered supranatu-ralism the only valid direction, still the interpretations of several doctrines bear the theology and formulation of Schleiermacher. He made it obvious that the views of rationalism are far from his views, and still, according to some suppositions, its doc-trines can be found also in his formulations. He was not familiar with the Hungari-an line of the theological liberalism, but it doesn’t mean that the German liberal thinking did not reach him. But according to our convictions, these views were far from him. He was looking for his own path, while he was open, but also critical to-wards the theological thinking of his time.
„A maga képére...” – Misszionáriusok fotográfiái mint az egyháztörténet forrásai
Authors: NAGY Károly Zsolt
Published: June 2017

„In his own image” – Photographs of Missionaries as the Source of Church History.
„The picture speaks for itself” – says the proverb, but how do we hear what it says and how do we understand its words? We are now in the age of visual information where visual content plays a role in every part of life. But we do not spend enough time looking at the pictures in detail. We spend a flash of time with them, and the pictures do not affect our consciousness, but our emotions. From this follows the question of how can we, as social scientists extract the contents of the photos? How can a photo be the source of the church history? This essay cannot, of course, give a perfect answer to the question, but it gives a brief introduction to the so-called „skills of visual literacy”, based on some photography relevant to Church history.
The management and organizational practices survey (MOPS): An overview
Authors: Buffington Catherine , Foster Lucia , Jarmin Ron , Ohlmacher Scott
Published: June 2017

This paper describes the Management and Organizational Practices Survey (MOPS), conducted by the U.S. Census Bureau in 2010 and 2015. The 2010 survey was the first-ever large scale survey of management practices in the United States. Enhancements for the 2015 survey include questions on two topics related to management: data and decision making (DDD) and uncertainty. This paper provides an overview of the existing literature on the role of management and organizational practices in firm performance, focusing on earlier efforts to measure these practices using survey data. The paper then describes the content and methodology of the MOPS.
Simulator Demonstrations of Different Retrofit Options of a Self-propelled Inland Vessel
Authors: Hargitai Csaba , Schweighofer Juha , Simongáti Győző
Published: June 2017

The project MoVe IT! (www.moveit-fp7.eu), funded by the Seventh Framework Programme of the European Union, was focussed on modernisation of inland waterway vessels by retrofitting. In order to stimulate an implementation of the results by the industry, visualization of the positive impacts was realised by a set of vivid demonstrators. In this paper, the demonstrations by simulators for a single screw motor cargo vessel of the type Johann Welker are described.The motion simulations are carried out by a custom made (for inland vessels developed) computer program, which use common naval architect force calculation algorithms and a new approximation theory for added masses.The simulator demonstrations comprise descriptions and visualisations of ship lengthening, application of different rudder and a new propulsion device. Five different cases are examined, the original vessel and four retrofit options.First retrofit variant is the lengthened vessel with original rudder and propeller. Other two analysis are performed changing only the rudder system. In fourth simulator demonstration the original propeller is changed to a pump propeller (a novel propulsion device).The environment are in the simulator demonstrations: constant draught of the vessel, and calm, infinite deep waterway.As results of simulator demonstrations the effects on fuel consumption and manoeuvrability are discussed in the paper.
A structural numerical model for the optimization of double pelvic osteotomy in the early treatment of canine hip dysplasia
Authors: Terzini Mara , Mossa Luca , Bignardi Cristina , Costa Piero , Audenino Alberto , Vezzoni Aldo , Zanetti Elisabetta
Published: June 2017

Background: Double pelvic osteotomy (DPO) planning is usually performed by hip palpation, and on radiographic images which give a poor representation of the complex three-dimensional manoeuvre required during surgery. Furthermore, bone strains which play a crucial role cannot be foreseen.

Objective: To support surgeons and designers with biomechanical guidelines through a virtual model that would provide bone stress and strain, required moments, and three-dimensional measurements.

Methods: A multibody numerical model for kinematic analyses has been coupled to a finite element model for stress/strain analysis on deformable bodies. The model was parametrized by the fixation plate angle, the iliac osteotomy angle, and the plate offset in ventro-dorsal direction. Model outputs were: acetabular ventro-version (VV) and lateralization (L), Norberg (NA) and dorsal acetabular rim (DAR) angles, the percentage of acetabular coverage (PC), the peak bone stress, and moments required to deform the pelvis.

Results: Over 150 combinations of cited parameters and their respective outcome were analysed. Curves reporting NA and PC versus VV were traced for the given patient. The optimal VV range in relation to NA and PC limits was established. The 25° DPO plate results were the most similar to 20° TPO. The output L grew for positive iliac osteotomy inclinations. The 15° DPO plate was critical in relation to DAR, while very large VV could lead to bone failure.

Clinical significance: Structural models can be a support to the study and optimization of DPO as they allow for foreseeing geometrical and structural outcomes of surgical choices.

ORCID iD

ALA: http://orcid.org/0000-0002-4877-3630

AV: http://orcid.org/0000-0003-2837-7822

CB: http://orcid.org/0000-0002-7065-2552

EZ: http://orcid.org/0000-0003-4121-6126

MT: http://orcid.org/0000-0002-5699-6009
Comparison of complications following tibial tuberosity advancement and tibial plateau levelling osteotomy in very large and giant dogs 50 kg or more in body weight
Authors: Barnhart Matthew , Kennedy Shawn , Naber Steven , Hans Eric
Published: June 2017

Objectives: To analyse and compare major complications in dogs ≥50 kg undergoing tibial tuberosity advancement (TTA) or tibial plateau levelling osteotomy (TPLO) for treatment of cranial cruciate ligament disease.

Methods: Medical records and radiographs of client-owned dogs (≥50 kg) treated for cranial cruciate ligament disease with either TTA or TPLO between January 2011 and November 2015 were reviewed. Ninety-one TTA cases and 54 TPLO cases met the study inclusion criteria. All complications within one year of surgery were recorded. Major complications were those requiring surgical revision or intervening medical therapy to resolve. Logistic regression analysis evaluated for associations with major complication occurrence. Major complications were statistically compared between TTA and TPLO treatment groups.

Results: Incidence of major complications following TTA and TPLO surgery were 19.8% and 27.8%, respectively. Surgical site infection (SSI) was the single most common major complication following both TTA (15.4%) and TPLO (25.9%) surgery. There were no significant differences between TTA and TPLO treatment regarding the rate of SSI, surgical revision, or overall occurrence of major complications. Postoperative antibiotic therapy significantly reduced the risk of a major complication in all dogs ≥50 kg (p = 0.015; OR: 0.201: 95%CI: 0.055–0.737).

Clinical significance: Major complications occurred frequently following TTA and TPLO treatment of cranial cruciate ligament disease in dogs ≥50 kg. The increased chance for SSI should be considered and postoperative antibiotic therapy is recommended.
Clinical outcome and complications of thoracic and pelvic limb stump and socket prostheses
Authors: Kulendra Elvin , Bishop Edith , Monk Michelle , Parsons Kevin , House Arthur , Phillips Andrew
Published: June 2017

Objectives: To describe the use, quality of life, compliance, complications, and outcome of animals fitted with stump socket prostheses.

Methods: Medical records of dogs fitted with a stump socket prosthesis were reviewed. Functional outcome, quality of life and complications were retrospectively assessed from an owner questionnaire.

Results: Thirteen stump socket prostheses (12 dogs) were fitted for a variety of reasons including trauma, congenital abnormalities, and neoplasia. Eight dogs had a good outcome overall and four a poor outcome. Quality of life (QOL) remained good or excellent in 10/12 dogs. Nine complications were seen in 7/12 dogs, most were manageable; surgical wound complications (n = 2) and pressures sores (n = 4) were the most frequently encountered. One dog suffered multiple complications. Thoracic and pelvic limb stump socket prostheses had a similar complication rate, however all animals with a poor outcome had a thoracic limb stump socket prosthesis; two were small breed dogs (under 10 kg) and two had bilateral thoracic limb abnormalities.

Clinical significance: Stump socket prostheses are feasible and versatile in animals. In correctly selected cases, good to excellent outcomes are possible. However, complications are frequent but often manageable. Further investigations are required into the risk factors for poor outcomes and prospective studies are required to assess changes in biomechanics, function, and QOL before and after fitting of a stump socket prosthesis. Until further evidence is available, careful consideration should be given before fitting bilateral thoracic limb stump socket prostheses or thoracic limb stump socket prostheses to small breed dogs.

Supplementary Material to this article is available online at https://doi.org/10.3415/VCOT-16-09-0127
Strategies in megasynthase engineering – fatty acid synthases (FAS) as model proteins
Authors: Fischer Manuel , Grininger Martin
Published: June 2017

Megasynthases are large multienzyme proteins that produce a plethora of important natural compounds by catalyzing the successive condensation and modification of precursor units. Within the class of megasynthases, polyketide synthases (PKS) are responsible for the production of a large spectrum of bioactive polyketides (PK), which have frequently found their way into therapeutic applications. Rational engineering approaches have been performed during the last 25 years that seek to employ the “assembly-line synthetic concept” of megasynthases in order to deliver new bioactive compounds. Here, we highlight PKS engineering strategies in the light of the newly emerging structural information on megasynthases, and argue that fatty acid synthases (FAS) are and will be valuable objects for further developing this field.
Impact of Ménière’s Disease on Significant Others’ Health and Lives
Authors: Manchaiah Vinaya , Pyykkő Ilmari , Levo Hilla , Kentala Erna
Published: June 2017

Background:Ménière’s disease (MD) is a chronic and, in part, intermittent illness that poses multiple challenges for both the physical and psychological well-being of patients, as well as on those around them. The patients face psychosocial consequences, which
include disruptions to life goals, employment, income, relationships, leisure activities, and daily living activities that also influence their family members and friends. However, there is a limited understanding of the impact of MD on significant others (SOs).Purpose:The current study
was aimed at identifying how the SOs of patients with MD respond to different aspects of the impact of the disorder on health and life (i.e., psychological aspects, activities, participation, and positive aspects).Research Design:The study employed a cross-sectional survey design.Study
Sample:The study sample was 186 SOs of patients with MD who were recruited through Finnish Ménière’s Federation.Data Collection and Analysis:Participants completed a 25-item structured questionnaire focusing on different aspects of the impact of the disorder
on health and life, and also provided some demographic information. Data were analyzed using Kruskal‐Wallis test, Pearson’s correlation, and K-means cluster analysis techniques.Results:Examination of response patterns suggests that the disorder had, on average, a
marginal effect on SOs’ psychological aspects, activities, and participation as the SOs generally focused on complaints. Interestingly, SOs reported some positive consequences as a result of their partners’ condition. The results show a limited association between SOs’ demographic
variables and response patterns. The Pearson’s correlation suggested a strong association between the subscales psychological aspects, activity limitations, and participation restrictions. Also, a weak negative correlation was observed among positive aspects and participation restrictions.
The cluster analysis resulted in three clusters, namely, (1) “nonengaged,” (2) “supportive,” and (3) “concerned.”Conclusions:The current study results identify that the SOs’ reaction to patients’ condition varies and this may be from coping
with victimization. Although the impact of MD on SOs is limited, some of the SOs may have more severe consequences and may require rehabilitation. The information gathered about SOs’ coping and adjustment in this study can also help while developing management and/or rehabilitation plan
for people with MD.
The Impact of Innovation on Store Managers’ Job Satisfaction: Evidence from Tunisian Retailing
Authors: Karmeni Kerim , Hamadi Abdelkader , Mesri Leila , Slim Ben Mimoun Mohamed
Published: June 2017

La présente étude a comme objectif d’analyser l’impact de l’innovation sur la satisfaction du travail dans les réseaux commerciaux. En particulier, nous testons des hypothèses sur l’effet de trois formes d’innovation (organisationnelle, procédé et produit) sur la satisfaction des gérants des points de ventes appartenant aux réseaux de distribution. L’analyse des données collectées auprès de 95 points de ventes appartenant aux réseaux de distribution implantés en Tunisie, moyennant la méthode PLS ( Partial Least Squares ), montre que seulement l’innovation organisationnelle qui affecte positivement la satisfaction des gérants des points de ventes. Ceci constitue une contribution à la compréhension de la gestion de l’innovation et ses conséquences dans le secteur de la distribution en Tunisie.
Les sociétaires des banques coopératives : quelle ubiquité ? Le cas des Banques Populaires
Authors: Ben Slimane Faten , Pallas Valérie , Rousselet Evelyne
Published: June 2017

Cet article vise à identifier les rôles que les banques coopératives attribuent à leurs sociétaires. L’étude empirique, réalisée à partir de l’analyse du discours institutionnel sur les sites Internet des 16 banques régionales du réseau des Banques Populaires, révèle que l’ubiquité du sociétaire n’est pas principalement fondée sur le principe historique de double qualité : un client détenteur de parts sociales. Cette caractéristique semble s’effacer au profit d’une utilité économique et territoriale plus large. Les Banques Populaires se représentent davantage le sociétaire comme une ressource contributrice au processus de création de valeur de sa banque.
L’Inde a-t-elle besoin d’être industrielle pour devenir une grande puissance mondiale ?
Authors: Hache Emmanuel , Bourcet Clémence
Published: June 2017

De la campagne autour du Shining India à la politique industrielle du Make in India , l’Inde continue à chercher sa place sur la scène internationale à côté de son dynamique voisin chinois. Le pays fait aujourd’hui valoir des atouts considérables : une croissance économique supérieure à 7 %, une population qui dépassera celle de la Chine autour de 2020, des technologies de pointe dans plusieurs secteurs. Mais pour devenir une puissance mondiale de premier plan, l’Inde cherche à densifier un secteur manufacturier encore peu présent sur la scène internationale, alors que son économie demeure largement basée sur les services. Amorcée en mars 2014, la politique du Make in India vise à répondre aux grandes problématiques que connaît le pays. Elle s’inscrit également dans le contexte plus large d’une dynamique asiatique de développement, au sein de laquelle Beijing a aussi lancé, en 2015, son programme Made in China 2025 . Derrière ces slogans se cachent certainement les arcanes des futures chaînes de production économiques internationales, et peut-être de la puissance indienne et chinoise au niveau mondial.
Politique interculturelle et gouvernance à niveaux multiples à Barcelone : Approche globale en matière d’intégration
Authors: Zapata-Barrero Ricard
Published: June 2017

L’objectif principal de cet article consiste à analyser l’approche globale (mainstreaming) adoptée par Barcelone dans sa politique interculturelle depuis le début de son processus d’immigration. Je pose trois questions-clés : a) pourquoi Barcelone a-t-elle été attirée par l’approche interculturelle dès 1997 ? b) comment pouvons-nous comprendre la consolidation de l’interculturalisme, et c) comment expliquer le succès de sa persistance constante (20 ans), en dépit de contextes migratoires/gouvernements politiques différents ? Nous verrons que le statut de Barcelone en tant qu’acteur clé au sein du système espagnol et catalan de gouvernance à niveaux multiples a constitué un facteur clé favorable. Je commencerai par décrire l’approche globale, avant de défendre l’argument selon lequel la dimension verticale a contribué à renforcer la légitimité de la dimension horizontale dans la mesure où elle a fourni un terreau favorable à l’épanouissement de l’interculturalisme. Je conclurai en soulignant que l’analyse de Barcelone contribue à apporter de nouvelles significations pour alimenter le débat relatif à la gouvernance à niveaux multiples dans plusieurs villes d’Europe. Remarques à l’intention des praticiens La gouvernance à niveaux multiples et les réseaux de villes influencent l’élaboration des politiques et la consolidation des politiques qu’adoptent les villes en matière de diversité. Il existe un lien présumé entre les politiques interculturelles et l’approche globale en matière de politiques de diversité. La relation entre les dimensions horizontale et verticale de la gouvernance à niveaux multiples joue un rôle clé dans la promotion d’un environnement permettant à ces politiques de s’épanouir.
Défis locaux et préoccupations nationales : Réactions au niveau municipal aux politiques d’établissement des réfugiés au Danemark et en Suède
Authors: Myrberg Gunnar
Published: June 2017

Le présent article examine la manière dont les politiques nationales danoises et suédoises concernant les réfugiés et les demandeurs d’asile sont perçues, ainsi que les réactions qu’elles suscitent, au niveau municipal dans les villes d’Aarhus et de Malmö. Comme nous le verrons dans l’article, les représentants municipaux ont pris la parole tant au Danemark qu’en Suède au milieu des années 1990, estimant que leurs municipalités devaient supporter un « fardeau d’accueil » qui excédait leurs capacités, et demandant avec insistance des changements au niveau des politiques nationales de répartition et de migration. Les réactions au niveau national ont toutefois été radicalement différentes au Danemark et en Suède. Aujourd’hui, cette différence se traduit non seulement sur le plan du nombre de primo-arrivants, mais aussi des pratiques municipales de présentation ainsi que des mémoires institutionnelles des agents municipaux Remarques à l’intention des praticiens Les conclusions présentées dans cette étude renvoient à la fois à la possibilité, pour les municipalités, d’avoir un impact direct sur les politiques nationales ; en l’occurrence, il s’agit principalement des politiques d’établissement des réfugiés, mais aussi de la manière dont les décisions politiques prises à un certain moment façonnent par la suite les structures d’opportunité politique, tant au niveau national que local.