bluuebunny/crossref_metadata_2025 huggingface dataset:
A Deep-Learning Approach to Driver Drowsiness Detection
Authors: Ahmed Mohammed Imran Basheer , Alabdulkarem Halah , Alomair Fatimah , Aldossary Dana , Alahmari Manar , Alhumaidan Munira , Alrassan Shoog , Rahman Atta , Youldash Mustafa , Zaman Gohar
Published: September 2023

Drowsy driving is a widespread cause of traffic accidents, especially on highways. It has become an essential task to seek an understanding of the situation in order to be able to take immediate remedial actions to detect driver drowsiness and enhance road safety. To address the issue of road safety, the proposed model offers a method for evaluating the level of driver fatigue based on changes in a driver’s eyeball movement using a convolutional neural network (CNN). Further, with the help of CNN and VGG16 models, facial sleepiness expressions were detected and classified into four categories (open, closed, yawning, and no yawning). Subsequently, a dataset of 2900 images of eye conditions associated with driver sleepiness was used to test the models, which include a different range of features such as gender, age, head position, and illumination. The results of the devolved models show a high degree of accountability, whereas the CNN model achieved an accuracy rate of 97%, a precision of 99%, and recall and F-score values of 99%. The VGG16 model reached an accuracy rate of 74%. This is a considerable contrast between the state-of-the-art methods in the literature for similar problems.
Determination of Lysergic Acid Diethylamide and 2-Oxo-3-Hydroxy-LSD in Blood: Validation and Comparison of Two Liquid Chromatography–Tandem Mass Spectrometry Methods
Authors: Dimitrova Alexandra , Di Milia Maria Grazia , Rensi Regina , Grassi Simone , Gualco Barbara , Vaiano Fabio
Published: September 2023

Lysergic acid diethylamide (LSD) is a powerful hallucinogen. Its detection is limited by its low dosage; moreover, LSD is rapidly metabolized into 2-oxo-3-hydroxy-LSD (O-H-LSD). In this study we validated two methods for determination of LSD and O-H-LSD in blood. Method #1 consisted in the upgrade of a previously developed procedure for detection of 163 compounds. Method #2 was specific for LSD and O-H-LSD. Analyses were performed through LC-MS/MS by dynamic (#1) and/or MRM mode (#2), in positive ionization. Transitions were: 324→223,208 m/z for LSD; 356→237,222 m/z for O-H-LSD. Validations were performed following the AAFS’s guidelines. Linearity was good for both methods. Sensitivity was in line with previously validated methods with LOQs at 0.0375 (#1) and 0.025 (#2) ng/mL for LSD and 0.01875 (#1) and 0.0125 (#2) ng/mL for O-H-LSD. Bias and %CV always met the acceptance criteria. RRs were >83%, except for O-H-LSD with method #1. The methods were successfully applied to two real cases. Method #1 proved to be useful for screening purposes, while method #2 can represent a sensitive and reliable tool for confirmation procedures.
Coconut Water: A Sports Drink Alternative?
Authors: O’Brien Brendan J. , Bell Leo R. , Hennessy Declan , Denham Joshua , Paton Carl D.
Published: September 2023

Coconut water is used as an alternative to conventional sports drinks for hydration during endurance cycling; however, evidence supporting its use is limited. This study determined if drinking coconut water compared to a sports drink altered cycling performance and physiology. In a randomized crossover trial, 19 experienced male (n = 15) and female (n = 4) cyclists (age 30 ± 9 years, body mass 79 ± 11 kg, V̇O2 peak 55 ± 8 mL·kg−1·min−1) completed two experimental trials, consuming either a commercially available sports drink or iso-calorific coconut water during 90 min of sub-maximal cycling at 70% of their peak power output, followed by a simulated, variable gradient, 20 km time trial. Blood glucose, lactate, sweat loss, and heart rate were monitored throughout the 90 min of sub-maximal cycling, as well as the time trial performance (seconds) and average power (watts). A repeated measures analysis of variance and effect sizes (Cohen’s d) analysis were applied. There were no significant differences (p ≥ 0.05) between the treatments for any of the measured physiological or performance variables. Additionally, the effect size analysis showed only trivial (d ≤ 0.2) differences between the treatments for all the measured variables, except blood glucose, which was lower in the coconut water trial compared to the sports drink trial (d = 0.31). Consuming coconut water had a similar effect on the cycling time trial performance and the physiological responses to consuming a commercially available sports drink.
The Antibacterial Performance of Implant Coating Made of Vancomycin-Loaded Polymer Material: An In Vitro Study
Authors: Alenezi Ali
Published: September 2023

Bacterial adhesion and biofilm formation on the surface of titanium implants are the main causes of implant-associated infection. An antibacterial coating on the implant surface can reduce the risk of biofilm formation. The aim of this study was to investigate the bactericidal effects of a van-comycin-loaded polymer coated on an implant surface. For this purpose, poly(N-isopropylacrylamide) (PNIPAAm) was first synthesized as a homopolymer or by co-polymerization with acrylamide (PNIPAAm-AAm) at a 5% weight ratio. Then, thin and uniform polymer coatings were prepared using the spin coating technique. The degree of surface hydro-philicity of the polymer coatings was evaluated by measuring the water contact angle (CA). For the antibacterial tests, the polymer-coated surfaces were loaded with vancomycin. The tests were performed in three conditions: on a glass surface (control), on a PNIPAAm-AAm-coated surface, and on a PNIPAAm-AAm-coated surface loaded with vancomycin. The death rates of the bacteria in contact with the coated surfaces were evaluated at different temperatures with fluorescence microscopy. A scanning electron microscopy (SEM) analysis of cross sections of the polymer coatings revealed a uniform thin film of approximately 200 nm in thickness. The water contact angle analysis performed at different temperatures revealed that the polymer-coated surfaces were more hydrophobic (CAs ranging between 53° and 63°) than the uncoated glass surface (CA ranging between 15° and 35°). The bacterial death rate, measured at 40 °C or while continuously switching the temperature between 37 °C and 40 °C, was higher in the presence of the surface coated with vancomycin-loaded PNIPAAm-AAm than when using the other surfaces (p-value ≤ 0.001). The vancomycin-loaded polymer coating evaluated in this study exhibited effective antibacterial properties when the polymer reached the phase transition temperature.
Three Convergence Results for Iterates of Nonlinear Mappings in Metric Spaces with Graphs
Authors: Zaslavski Alexander J.
Published: September 2023

In 2007, in our joint work with D. Butnariu and S. Reich, we proved that if for a self-mapping of a complete metric that is uniformly continuous on bounded sets all its iterates converge uniformly on bounded sets, then this convergence is stable under the presence of small errors. In the present paper, we obtain an extension of this result for self-mappings of a metric space with a graph.
Risk Assessment of Heavy Metals in Sediment Samples from the Mae Chaem River, Chiang Mai, Thailand
Authors: Kawichai Sawaeng , Prapamontol Tippawan , Santijitpakdee Teetawat , Bootdee Susira
Published: September 2023

Heavy metals are significant environmental pollutants that are recognized as posing a potential health hazard to human beings. We investigated the concentrations of the heavy metals As, Cd, Cr, Cu, Ni, Pb, and Zn in surface sediments collected from the Mae Chaem River in Chiang Mai, Thailand, during the dry season in 2021. The mean concentrations of heavy metals in sediments were, in decreasing order, Zn > Cr > As > Pb > Ni > Cu > Cd. The mean values of As, Cd, Cr, and Cu were determined to be 32.5 ± 18.3, 0.33 ± 0.07, 45.8 ± 11.9, and 21.9 ± 7.42 mg Kg−1, respectively. These levels are higher than their standard levels in Thailand, namely 10.0, 0.16, 45.5, and 21.5 mg Kg−1, respectively. Principal component analysis (PCA) revealed that the primary origins of heavy metal contamination are predominantly attributed to residential settlements and agricultural areas. The hazard quotient (HQ) was used to estimate the non-carcinogenic risk of exposure to heavy-metal-bound surface sediments for both children and adults. The results showed that the HQ values for both groups were less than 1.0 (HQ < 1.0), indicating no risk. Moreover, assessment of the long-term risk for ingestion of toxic metals indicated no risk (<10−6) based on the lifetime cancer risk (LCR). However, the LCR values of As and Cr were 5.3 × 10−6 and 2.5 × 10−6, respectively, demonstrating the most elevated LCR among the hazardous metals in terms of children’s exposure. Therefore, it is possible that children living in agricultural areas and participating in activities around the study area may be exposed to elevated concentrations of As and Cr.
Expanded Polystyrene-Debris-Induced Genotoxic Effect in Littoral Organisms
Authors: Chelomin Victor Pavlovich , Dovzhenko Nadezda Vladimirovna , Slobodskova Valentina Vladimirovna , Mazur Andrey Alexandrovich , Kukla Sergey Petrovich , Zhukovskaya Avianna Fayazovna
Published: September 2023

Expanded polystyrene (EPS) is a major component of plastic debris in the environment, including coastal and littoral zones. EPS is widely used in various industries including fish farming and aquaculture, which poses a serious potential threat not only to cultured hydrobionts but also to all living organisms, including humans. This paper presents the results of experimental studies on the effects of EPS (0.024 m2/L) on marine mollusks Mytilus trossulus and Tegula rustica, which are typical inhabitants of the upper littoral of Peter the Great Bay (Sea of Japan), belonging to different systematic groups and differing in the type of nutrition. The results of biochemical marker analysis showed the development of oxidative stress processes. Thus, increasing malondialdehyde content relative to control values was registered in the digestive glands of M. trossulus and T. rustica. In the cells of the digestive glands of M. trossulus, integral antioxidant activity decreased more than 1.5 times compared with that of the control. The change in the concentration of protein carbonyls was unchanged in M. trossulus, whereas in T. rustica, there was a 1.5-fold increase. EPS exposure also resulted in significant DNA damage in the studied mollusks—the damage level increased 2.5-fold in M. trossulus and 1.5-fold in T. rustica relative to the control, indicating the genotoxic potential of EPS litters.
Prognostic Performance of Inflammatory Biomarkers Based on Complete Blood Counts in COVID-19 Patients
Authors: Gambichler Thilo , Schuleit Nadine , Susok Laura , Becker Jürgen C. , Scheel Christina H. , Torres-Reyes Christian , Overheu Oliver , Reinacher-Schick Anke , Schmidt Wolfgang
Published: September 2023

With the end of the pandemic, COVID-19 has entered an endemic phase with expected seasonal spikes. Consequently, the implementation of easily accessible prognostic biomarkers for patients with COVID-19 remains an important area of research. In this monocentric study at a German tertiary care hospital, we determined the prognostic performance of different clinical and blood-based parameters in 412 COVID-19 patients. We evaluated the neutrophil-to-lymphocyte ratio (NLR), systemic immune-inflammation index (SII), pan-immune-inflammation value (PIV), and absolute eosinopenia (AEP, 0/µL) of COVID-19 patients (n = 412). The Siddiqui and Mehra staging proposal, the WHO clinical progression scale, and COVID-19-associated death were used as COVID-19 outcome measures. With respect to Siddiqi and Mehra staging, patient age of older than 75 years, high C-reactive protein (CRP), absolute eosinopenia (AEP), cardiovascular comorbidities, and high ferritin were significant independent predictors for severe COVID-19. When outcome was determined according to the WHO clinical progression scale, patient age of older than 75 years, high CRP, high LDH, AEP, high neutrophil-to-lymphocyte ratio (NLR), and the presence of pulmonal comorbidities were significant independent predictors for severe COVID-19. Finally, COVID-19-associated death was predicted independently by patient age of older than 75 years, high LDH, high NLR, and AEP. Eosinopenia (< 40/µL) was observed in 74.5% of patients, and AEP in almost 45%. In conclusion, the present real-world data indicate that the NLR is superior to more complex systemic immune-inflammation biomarkers (e.g., SII and PIV) in COVID-19 prognostication. A decreased eosinophil count emerged as a potential hallmark of COVID-19 infection, whereas AEP turned out to be an accessible independent biomarker for COVID-19 severity and mortality.
An In-House ELISA for Treponema Antibodies in Bulk Milk as Part of a Monitoring Tool for Claw Health in Dairy Herds
Authors: Holzhauer Menno , Mars Jet , Holstege Manon , van der Heijden Harold
Published: September 2023

Digital dermatitis (DD) is a painful inflammation at the coronary band of the claws, a major cause of lameness in cattle and associated with infections with several Treponema spp. Clinical inspection of the feet is the best way to diagnose DD, but this is laborious and stressful for cattle. A simple diagnostic tool was developed to monitor DD prevalence at the herd level. An antibody ELISA based on antigens from four different Treponema spp. has been developed and validated in two field studies. In one study, bulk milk and individual milk samples of seven dairy herds, of which clinical claw scores were obtained, were tested. In the second study, bulk milk was tested from 110 herds of which clinical scores were obtained. A weak correlation between clinical scores of cows and the ELISA results in individual milk samples was observed. The ELISA response in bulk milk was higher in herds with higher mean clinical scores. Using the ELISA results in bulk milk, herds with a low or high proportion of cattle with DD lesions could be distinguished. This ELISA is useful to obtain insight into the DD status at the herd level, and is nowadays being used in a claw health monitoring program for dairy cattle in the Netherlands.
Uncertainty Quantification and Simulation of Wind-Tunnel-Informed Stochastic Wind Loads
Authors: Duarte Thays G. A. , Arunachalam Srinivasan , Subgranon Arthriya , Spence Seymour M. J.
Published: September 2023

The simulation of stochastic wind loads is necessary for many applications in wind engineering. The proper-orthogonal-decomposition-(POD)-based spectral representation method is a popular approach used for this purpose, due to its computational efficiency. For general wind directions and building configurations, the data-informed POD-based stochastic model is an alternative that uses wind-tunnel-smoothed auto- and cross-spectral density as input, to calibrate the eigenvalues and eigenvectors of the target load process. Even though this method is straightforward and presents advantages, compared to using empirical target auto- and cross-spectral density, the limitations and errors associated with this model have not been investigated. To this end, an extensive experimental study on a rectangular building model considering multiple wind directions and configurations was conducted, to allow the quantification of uncertainty related to the use of short-duration wind tunnel records for calibration and validation of the data-informed POD-based stochastic model. The results demonstrate that the data-informed model can efficiently simulate stochastic wind loads with negligible model errors, while the errors associated with calibration to short-duration wind tunnel data can be important.
Associating Economic Growth and Ecological Footprints through Human Capital and Biocapacity in South Asia
Authors: Mehmood Usman , Aslam Muhammad Umar , Javed Muhammad Adil
Published: September 2023

The ecological footprint (EF) has been used as an environmental indicator in most of the past research. Due to the complex linkages between economic growth and human development, EF has been inadequately understood in policy making. This research attempts to investigate the impacts of economic growth, human capital, biocapacity, and urbanization on the factors affecting the ecological footprint (EF) of five South Asian countries. To provide empirical evidence, this study utilizes the annual data from 1990 to 2022 for Pakistan, India, Bangladesh, Nepal, and Sri Lanka. The findings confirm the positive contribution of GDP, human capital, biocapacity, and urbanization to EF. The causality analysis shows feedback association between GDP and EF, human capital and EF, and biocapacity and EF.
Critical analysis of the definitions of the category “valuation” in accounting and non-accounting sources
Authors:   Federal State Autonomous Educational Institution of Higher Education “Lobachevsky State University of Nizhny Novgorod”, Nizhny Novgorod, Russia, Druzhilovskaya E.S.
Published: September 2023

Valuation is undoubtedly the basis of accounting and reporting of any organization. At the same time, as our research have shown, to date, the accounting regulations do not provide a definition of the valuation, and in the scientific and educational literature there is no consensus of scientists on this issue. This article critically analyzes various points of view regarding the interpretation of the category “valuation”, presented in Russian and foreign accounting and non-accounting sources of recent decades. The following research methods were used: analysis and synthesis,comparison, grouping method, logical approach, systematic approach, analogy method. As a result of the research, this paper presents the author’s view of the existing definitions of the category “valuation” in relation to their applicability in modern accounting and reporting. The results reflected in this article will be of interest to a wide range of readers who analyze various problems of Russian and foreign accounting and reporting, including the valuation of accounting objects and reporting elements. In addition, the results obtained in this work can be applied in the educational process of higher educational institutions and in the practical work of accounting departments. In addition, the results of this study can be used in the development and improvement of relevant domestic and foreign regulatory documents on accounting and reporting.
Mechanisms for the implementation of state "green" procurement in Russia
Authors:   Plekhanov Russian University of Economics, Moscow, Russian Federation, Kovalenko Yu.N. , Kovalenko S.N. ,   Plekhanov Russian University of Economics, Moscow, Russian Federation
Published: September 2023

This study examines state “green” purchases, as well as their impact on various spheres of life. The economic, environmental and social benefits of “green” public procurement have been identified, which can help improve not only the ecology of the country, but also the standard of living of its citizens. The legislation related to this type of procurement is also presented, environmental requirements for goods, works, and services that are mandatory for indication in the procurement of state organizations of the city of Moscow are given. The experience of foreign countries was cited as an example of the development of the public “green” procurement sector. The study analyzes the mechanism of implementation of state “green” procurement in Russia by the example of the application of certain environmental requirements in the implementation of the public procurement process in Moscow, provides a number of obstacles to the development of “green” public procurement in the Russian Federation. The conclusions are formulated on the basis of the analysis of the state “green” procurement in Russia.
Modern values of the Kazakhstan youth: trends and analysis
Authors:   Faculty of Philosophy and Political Science, Al-Farabi Kazakh National University, PhD student of the Department of Philosophy, Sociology and Cultural Studies, Moscow University for the Humanities, Almaty, Republic of Kazakhstan, Maylykutova Mariya Dzhumakodzhaevna
Published: September 2023

The article analyzes the dynamics of young people’s life orientations and values, presented in the context of the life of society. In the conducted study, one of the problems was to determine how young people assess various life values. Research objectives: 1) selection of an unlimited number of values that young people considered significant, 2) compilation of a hierarchy of three to five values most significant for young people. The article examines the views on the social and spiritual values of the Kazakhstan youth in modern society. The value orientations of the Kazakhstan youth and their age and socioprofessional groups have been studied. The main factors influencing the formation of value orientations of the Kazakhstan youth and the degree of stability and formation of values have been identified and analyzed. The article analyzes the theoretical and practical conclusions about the features of the intergenerational dynamics of life requirements and youth strategies, as well as practical conclusions that help strengthen and increase the value potential of the youth of Kazakhstan, adequate to the conditions for the formation of new social relations.
Social media as a new forum for youth communication: from the advantage to destruction
Authors:   Academy of Federal Guard Service Orеl, Russia, Malik Elena Nikolayevna
Published: September 2023

Digital epoch has identified the unifying role of information in various areas of society. Today, social networks present themselves with a new forum that allows people to exchange ideas, establish contacts, get education, and enjoy new creative knowledge and technology. The purpose of this study is to conduct a comprehensive analysis of online communications on social media. The advantage of social media is also the elimination of communication barriers and the creation of decentralized communication channels, which is especially important for youth. However, the analysis showed that, along with positive characteristics, it is important to assess the destructive impact of social networks on young users. The method of system analysis revealed the main risks and threats of cybersocialization of youth. Social networks can serve as destructive content, become an instrument for committing crimes and countermeasures, and weave into extremism and terror. Digital services have opened doors for a new type of threat to social media — social engineering. The author made a reasoned conclusion that in order to reduce the destructive impact of social networks on the young generation, measures of increased state control over their activities are necessary. Also, a productive step in this direction will be the self-control of social media users for their digital hygiene and information literacy.
Legal linguistics and its role in modern legal proceedings in the Federal Republic of Germany
Authors:   Interstate Educational Institution of Higher Education «Russian-Armenian University», Department of Political Science of the Institute of Law and Politics, Yerevan, Ustinovich Elena Stepanovna
Published: September 2023

The correct linguistic interpretation is widely used in contemporary co-production. Correct linguistic interpretation-a particular form of linguistic investigation into the entire establishment of the existence, subject to evidence in the frame of an arbitrary, civil or angular process. Linguistic investigation, as well as another form of experimental investigations, indicates the establishment of facts, if the facts cannot be established in any way, but only with the help of attraction of the face, special knowledge in the field of linguistics. All this was a method of linguistic analysis used in the Russian co-production in the distribution of part according to the frequency and dostoy, part of the reputation, the humanization of the rights of the author in the production of advertising products, etc.d. in relation to what, one of the active development of interdisciplinary research methods on the style of jurisprudence and Linguistics, there is, unconditionally, the right linguistics. The fact that the development of scientific-methodological characterisation, scientific publications, allows them to make practical application of linguistic expertise in co-production as in the use of native and foreign languages, publicly deficient. The development of the Institute of legal linguistics results in different countries. It is always an interest of its own, as a form of life that flows in the countries with the glubby traditions of the right. In life, a country worthy of opting for the Federal Republic of Germany in the development of university scientific schools of legal linguistics.
TRENDS OF ARCHITECTURAL FORMATION AND URBAN PLANNING ARRANGEMENT OF THE LARGEST STADIUMS
Authors: Skoblickaya Yu.
Published: September 2023

Currently, Russia at the state level actively supports and popularizes sports and a healthy lifestyle. In this regard, the development of sports infrastructure facilities, including demonstration ones, such as stadiums, is underway. The article briefly describes the world experience in the formation of the planning structure of stadiums. Five years after the commissioning of the stadiums leased as part of the 2018 World Cup, an analysis of the functional and planning structure is carried out, the impact on the transformation of the adjacent territories is determined. On this basis, the features of the urban planning of the largest stadiums are identified. Taking into account the location, the main layout schemes are identified and described, the enlarged most characteristic aspects of the functional and planning structure of the largest modern stadiums are presented. Modern trends in the formation of the planning structure of stadiums related to urban planning and technological aspects are presented. Three options for the location of stadiums are described, in view of the urban planning situation. In accordance with this, the general plan structure and the planning structure of the facility are determined. Modern stadiums are multifunctional objects that have a complex planning structure with the possibility of transformation for holding various kinds of events, as well as including different functional objects taking into account the specific urban planning situation.
METHODS FOR ASSESSING MECHANICALLY ACTIVATED MINERAL RAW MATERIALS FOR COMPOSITE BINDERS
Authors: Sival'neva M. , Strokova V. , Nelyubova V. , Ogurtsova Yu. , Orehova T. , Botsman L. , Necvet Dar'ya
Published: September 2023

In the conditions of constantly increasing construction volumes, there is a necessity to transfer to environmentally efficient technologies for the production of building materials in order to reduce industrial pressure on the ecosphere and ensure rational subsoil use. One of the solutions is to reduce cement consumption by using composite binders with a reduced proportion of the clinker component. Improving the quality of composite binders is possible due to the preliminary activation of the surface of raw components. One of the most effective methods of activating raw materials is mechanical activation. A reasonable choice of its method and mode is possible only on the basis of the results of comprehensive studies in the system "the object of mechanical activation – the instrument of mechanical activation – the indicator of mechanical activation – the product of improvement by methods of mechanical activation". A comprehensive determination of the activity of mechanoactivated mineral raw materials as an indicator of the effectiveness of mechanoactivation includes the use of various research methods and evaluation of: the area of the interface boundary, granulometric composition, morphostructural features, sorption capacity, donor-acceptor surface centers, the energy state of the system and other parameters. The paper proposes a decomposition of the methodology for evaluating mineral raw materials from the position of mechanical activation in the production of composite binders. The use of this methodology will make it possible to rank mineral raw materials of natural and technogenic origin, optimize the process of mechanical activation from the point of view of choosing a rational method and develop generalized recommendations for the selection of technological modes of milling, taking into account the genesis of raw materials for obtaining active mineral components of composite binders of various composition, type of hardening and functional purpose. The development and implementation of the principles of rational selection of mineral raw materials components, based on the example of their application in composite binders, will ensure the specified functional properties and implement a predictive assessment of the performance characteristics of building composites as a whole.
PRINCIPLES OF INVESTMENT ATTRACTIVENESS OF TERRITORIES OF INDUSTRIAL HERITAGE OF SUGAR FACTORIES MIDDLE XIX – EARLY XX CENTURIES
Authors: Tsvetkova Yu. , Perkova M.
Published: September 2023

Industrial heritage objects reflect the history of the nation, the peculiarities of its thinking, and also have great potential in the context of the sustainable development of small towns and villages in which they are located. Sugar factories of the Central Black Earth region are historically city-forming enterprises. However, at the moment, industrial territories that do not perform a city-forming function, on the one hand, and an acquired socio-cultural function as a significant cultural heritage, on the other hand, have degraded and are partially in a ruined state. The study considers the factors affecting the investment attractiveness of industrial heritage objects of sugar factories: restrictions on the creation of a new function, location in small towns and rural settlements, low transport accessibility, the problem of property rights, the unsatisfactory state of the territory and objects of industrial heritage, imperfection of the legislative base in the field of cultural heritage preservation, lack of tourist and recreational attractiveness. The features in the legal documentation that negatively affect the investment attractiveness of the object of cultural heritage are revealed. The principles of investment attractiveness based on the resolution of urban conflicts are proposed, which are recommended when adapting the industrial heritage of sugar factories of XIX – early XX centuries It is assumed that the application of the developed principles for the territories of the industrial heritage of sugar factories will increase their level of attractiveness for the investor (public/private).
Continuité et discontinuité de la transmission de l’emploi de l’alsacien dans deux familles alliées
Authors: Tabouret-Keller Andrée
Published: September 2023

Il s'agit de deux familles d'origine alsacienne alliées par un mariage, l'une étant plus urbanisée et d'un niveau socioculturel plus élevé que l'autre qui reste surtout rurale quoique non-agricole. L'enquête porte sur quatre générations, les indicateurs de l'emploi linguistique sont la ou les langues employées dans le foyer familial par les parents entre eux, quand ils s'adressent à leurs enfants, éventuellement à leurs petits enfants, et par ceux-ci quand ils s'adressent à leurs parents ou grands-parents. La résidence et la profession font également partie des données mises en oeuvre pour établir le parcours sociolinguistique de ces familles et pour analyser les facteurs en jeu dans l'évolution des usages linguistiques.
La communication familiale lorsqu'un ou plusieurs membres sont sourds
Authors: Mottez Bernard
Published: September 2023

On envisage de façon cursive différents cas de figure selon la place du (des) sourd(s) dans la famille. On se centrera sur les familles où les deux parents sont sourds et natif de la LSF (langue des signes française) et où au moins un des enfants est entendant. Quelle langue (LSF, un pidgin LSF-français, français) est utilisée entre les uns et les autres et selon les contextes ? Même chose pour les interactions avec des personnes extérieures à la famille (amis, membres de la famille étendue, tous les ’’autres'' en général de la société entendante). Jusqu'à quel âge le jeune entendant se considère-t-il et est-il considéré par les membres de la communauté des sourds comme un sourd (culturellement) ?
Cetoacidose Diabética: fisiopatologia, diagnóstico e abordagem terapêutica
Authors: Lima Paola Tássia Freitas Mendonça , Cazzoletti Giulia , Passos Jhon Rollyman Carvalho , Silva Ricardo Rúbio Campos , Rodrigues Lucca Aires Porto , Nogueira Júlia Carvalho , Duarte Alice Lima Dias , Amaral Maria Paula Roman
Published: September 2023

A cetoacidose diabética (CAD) representa uma das complicações agudas mais graves do diabetes mellitus, caracterizada por hiperglicemia, cetogênese aumentada e acidose metabólica. Este artigo visa oferecer uma análise abrangente da fisiopatologia, diagnóstico e abordagem terapêutica da CAD. A insuficiência de insulina e o aumento de hormônios contrarregulatórios, como o glucagon, resultam em uma produção excessiva de corpos cetônicos e glicose hepática, contribuindo para a hiperglicemia e acidose. Clinicamente, os pacientes podem apresentar desidratação, hálito cetônico, taquipneia e alterações do estado mental. O diagnóstico se baseia em critérios clínicos e laboratoriais, destacando-se glicemias elevadas, acidose metabólica e presença de corpos cetônicos no sangue e urina. A abordagem terapêutica envolve a reposição volêmica, correção da hiperglicemia com administração de insulina, reposição de eletrólitos e tratamento das causas subjacentes. O reconhecimento precoce e a gestão apropriada são cruciais para reduzir a morbidade e mortalidade associadas. A educação do paciente sobre o controle glicêmico e o reconhecimento de sintomas é fundamental para a prevenção.
Transtorno do Espectro Autista em meninas: uma análise comparativa envolvendo estudos de gênero e possível sub reconhecimento na população feminina
Authors: Fink Beatriz Kaminski , Moreira Andressa Gabrielle , De Lima Sofia Santos
Published: September 2023

Objetivo: A maior prevalência em meninos com Transtorno do Espectro Autista (TEA) sugere modelos comportamentais e vieses masculinos nos atuais instrumentos relevantes para a avaliação diagnóstica. O atual estudo propõe descrever o perfil epidemiológico de pacientes com Transtorno do Espectro Autista (TEA) em crianças de um serviço público de Brasília, dando enfoque a possíveis diferenças de gênero, a fim de incentivar novos trabalhos sobre o tema. Metodologia: Estudo realizado em 2 etapas. A primeira consistiu em uma análise retrospectiva de prontuários dos pacientes e a segunda se deu pela aplicação de questionários direcionados aos responsáveis das crianças, avaliando os critérios do DSM-5 e aplicando os instrumentos diagnósticos ASSQ, ABC e M-CHAT. Resultados: Não foram encontradas diferenças epidemiológicas entre os grupos. Nos critérios do DSM-5 foi observada distribuição diferente dos domínios entre meninos e meninas. No ASSQ, ambos os grupos obtiveram pontuação semelhante e no ABC, as meninas obtiveram maior pontuação. O M-CHAT -CHAT foi desconsiderado para análise, pois havia apenas 1 paciente elegível para aplicação. Conclusões: Percebe-se que existem diferenças no diagnóstico de meninas com TEA, sendo que nas meninas o predomínio dos critérios A e B do DSM-V (comunicação e interação social, padrões restritivos e repetitivos de comportamento), enquanto que nos meninos há uma distribuição mais homogênea na sintomatologia e na gravidade. Mais estudos sobre esse tema ainda muito desconhecido são necessários.
The Organ of Vision Lesions in Some Hemoblastoses
Authors: Воробьева М.В.
Published: September 2023

В статье рассматриваются глазные проявления при гемобластозах. Представлены подробное описание повреждения внутриглазных и внеглазных структур, включая поражение орбиты и придаточного аппарата глаза, а также нейроофтальмологические изменения при наиболее распространенных формах лейкоза и лимфомах. Рассмотрены их первичные клинические проявления, частота их выявления, а также механизмы развития, которые связаны как с прямой инфильтрацией различных структур глаза, так и со вторичными нарушениями системы гемостаза, анемией и тромбоцитопенией. Особое внимание уделяется маскарадному синдрому – характерному признаку опухолевого процесса в глазу. Также оценены влияние терапии на орган зрения, изменения, развивающиеся на фоне иммунодефицита в результате токсического воздействия полихимиотерапии, таргетной и лучевой терапии, а также побочные эффекты аллогенной трансплантации гемопоэтических стволовых клеток, в частности развитие реакции «трансплантат против хозяина» в глазу реципиента.

The article discusses ocular manifestations in hemoblastosis. A detailed description of the damage to intraocular and non-ocular structures, including damage to the orbit and appendage of the eye, as well as neuro-ophthalmological changes in the most common forms of leukemia and lymphoma, is presented. Their primary clinical manifestations, their frequency of detection, as well as the mechanisms of development associated with both direct infiltration of various structures of the eye and secondary disorders of the hemostasis system, anemia and thrombocytopenia are considered. Special attention is paid to the masquerade syndrome – a characteristic feature of the neoplastic process in the eye. The effect of the therapy on the organ of vision, changes developing against the background of immunodeficiency as a result of the toxic effects of polychemotherapy, targeted and radiation therapy, as well as side effects of allogeneic hematopoietic stem cell transplantation, in particular, the development of a graft-versus-host reaction in the recipient’s eye, are also considered.
The prioruty directions of child and adolescent health care in the Russian Federation
Authors: Zagoruychenko Anna A. , Karpova Oksana B. , Bashkueva Elena Yu.
Published: September 2023

The article defines the priority areas for the protection of the health of children and adolescents, carried out a content analysis of the legal framework, revealed a negative trend in the prevalence of pathology in this population group. Particular attention has to be paid to the consistency and interdepartmental systemic approach that takes into account territorial features in the formation of strategic priorities for regional health care, especially within the framework of previously approved regional programs for the development of children's health care, and the results obtained can become the basis for making effective and competent management decisions by territorial health authorities.
Comparasion of composition of brake pad hardness and wearness
Authors: Mulia Mulia
Published: September 2023

This study aims to identify the most optimal material composition in achieving the best combination of hardness and wear. The experimental method was conducted using a special test bed designed to test the mechanical properties of various material compositions. The material specimens used were weighed before and after the test to calculate the wear rate by observing the change in specimen mass. The results showed that the 50:50 material composition performed significantly better than the 60:40 composition in terms of hardness and wear properties. These findings suggest that the 50:50 composition may be a superior choice in various applications where a combination of strength and wear resistance is required, such as in the manufacturing industry, materials engineering, or the automotive sector. This research provides valuable insights into material selection that can improve the performance and durability of the final product.
Goods, Services and Environmental Impacts Economic Valuation Methodologies
Authors:   Colegio de Postgraduados Campus Montecillo, RUIZ-SANDOVAL Daniela , SANDOVAL-SALAS Fabiola ,   Colegio de Postgraduados Campus Montecillo, ARANA-CORONADO Oscar Antonio ,   Colegio de Postgraduados Campus Montecillo, Stéphane GODBOUT ,   Colegio de Postgraduados Campus Montecillo
Published: September 2023

All human activity causes impacts on the environment, and this generates changes or alterations in the ecosystem services that ecosystems provide us. However, it is difficult to know the price or the cost that these impacts generate in the economy of a place, since very few goods and services that are commercialized in a market. This paper provides a general framework for the economic valuation of goods, services and environmental impacts, which ranges from traditional forms of valuation such as the hedonic price method or contingent valuation, to some non-traditional ones such as the multicriteria method or the benefit transfer method.
Guía para la identificación de Algas en Sabancuy, Campeche, México
Authors:   Universidad Autónoma de Campeche, MALDONADO-MONTIEL Teresita del Niño Jesús , CHAN-KEB Carlos Armando ,   Universidad Autónoma de Campeche, AGRAZ- HERNÁNDEZ Claudia Maricusa ,   Universidad Autónoma de Campeche, PERÉZ-BALÁN Román Alberto ,   Universidad Autónoma de Campeche
Published: September 2023

Algae are autotrophic organisms and thallophytes are the main component of plankton and marine benthos. It is the group most affected by climate change variations when performing photosynthesis and is the main base of the food chain in the ocean and world. This book is developed in 3 chapters: Chapter 1 Phycology. the background is described, where it is mentioned that there are few phycofloristic studies and inventories in the State of Campeche compared to the rest of the Mexican coast and given the great diversity of algae in the tropics due to its vast morphology, size and cellular structure, color are key to recognition, thus derives the problem of addressing with this guide to identify the algae of Sabancuy, Campeche Mexico. In Chapter 2 Methodology for the Collection and Recognition of Algae. It is proposed where and how the collection was carried out, which was established at the limit of a 60 m transect perpendicular to the coastline parallel to it by using GPS to register the place, the collections were carried out by means of basic snorkeling for the entire quadrant. The basic elements to make a quick and assertive identification. Using color, size, external morphological structures such as type of thallus and branching, frond, apex structure, phyllodes, stolon, rhizoids, formade, reproduction structures, flotation structures, among others. In Chapter 3 Morphology and Species Recognition. The images of algae collected annually in the period 2006 to 2018 and 2022 are presented. Likewise, a phycofloristic list of 42 species distributed in three divisions is presented: Chlorophyta (16 species and 9 genera), in Rhodophyta (21 species and 15 genera) and in the Division Heterokontophyta (5 species and 4 Genera). For each division, it is described from the morphology and the external characteristics of the collected specimens were considered for recognition and references for the elaboration of a guide and the identification of algae for the area. The description of the morphology of the algae was supported by authors with a recognized trajectory in the field.
An Evaluation in the Perspective of Public Interest in the Privatization and Regeneration of Public Lands: İstanbul
Authors: ALP Jülide
Published: September 2023

Urban regeneration has become one of the most significant instruments for the urban planning process particularly after the 1980’s with the effects of globalization and the acceleration of the race between cities. Thus, the metropolitan cities that stand out with their economic performance, cultural/traditional identity, and tourism potential have been restructured due to the social, cultural, technological, and economic changes and expectations that spread throughout the world. Cities known for their industrial areas and productions in the past are now turning into innovative productions and new prestige areas where the service sector is concentrated. In recent years, old industrial areas, warehouses, which had lost their former functions, have undergone the urban transformation processes. More recently, public lands located in city centers have been incorporated into the agenda of urban regeneration. Privatization of public lands is the most basic approach in such regeneration processes and therefore protecting public interest is the most critical issue. The main objective of this study is to identify the role of privatization policies in relation to the urban regeneration process and to provide an analysis of several urban regeneration projects in İstanbul.
Üçüncü Sınıf Türkçe Dersi Okuma Metinlerindeki Matematiksel Dil
Authors: AŞIKCAN Mehmet , UYGUN Neşe
Published: September 2023

Araştırmanın amacı; matematiksel dil açısından üçüncü sınıf Türkçe dersi okuma metinlerinin incelenmesidir. Araştırma nitel araştırma deseninde doküman incelemesi ile gerçekleştirilmiştir. Araştırmanın veri kaynakları; Millî Eğitim Bakanlığı (MEB) tarafından 2022-2023 eğitim-öğretim yılı için önerilen Millî Eğitim Bakanlığı Yayını ve Gizem Yayıncılık’a ait üçüncü sınıf Türkçe ders kitaplarıdır. Ders kitaplarından 16 metin (sekiz hikâye edici ve sekiz bilgilendirici) seçilmiştir. Metinler, matematik dersi öğretim programı öğrenme alanlarındaki (sayılar ve işlemler, geometri, ölçme ve veri işleme) matematiksel dil ifadelerine göre incelenmiştir. Araştırma sonucunda, incelenen metinlerde veri işleme haricinde sayılar ve işlemler, geometri ve ölçme öğrenme alanlarında matematiksel ifadelerin kullanıldığı saptanmıştır. Hikâye edici metinlerde (her iki yayınevinde) en çok ölçme; bilgilendirici metinlerde MEB Yayını ders kitabında en çok sayılar ve işlemler ve Gizem Yayıncılık ders kitabında en çok ölçme öğrenme alanına ilişkin matematiksel dil ifadelerine yer verilmiştir. Her iki kitapta matematiksel dil kullanımı hikâye edici metinlerde bilgilendirici metinlere kıyasla daha fazladır.
Hemangioendotelioma Retiforme en Tórax: reporte de un caso
Authors: Trujillo Ramírez Raúl , Sosa Cruz Andres Gustavo , Montes Osorio Mario German
Published: September 2023

Introducción El hemangioendotelioma retiforme es una neoplasia de grado intermedio o potencialmente maligna, su incidencia es entre la segunda y cuarta década de la vida, más frecuente 2:1 en mujeres, la etiología es incierta, se manifiesta generalmente como lesión nodular o en forma de placa en tronco o extremidades, el diagnostico es por histopatología e inmunohistoquímica, su tratamiento es resección de la lesión, con una recurrencia del 60% posterior al manejo quirúrgico. Caso clínico Se describe un caso atípico de hemangioendotelioma retiforme en tórax; de un femenino de 43 años, su padecimiento inicia con aumento de volumen de 6 meses en axila derecha, acompañándose de dolor y limitación de la movilidad; se realiza tomografía de tórax con reporte de tumoración del musculo pectoral de 83 mm, se realiza exéresis de tumoración con reporte histopatológico de: hemangioendotelioma retiforme e inmunohistoquímica positiva a CD34.
LETÁLIDE CUTÁNEA COMO MANIFESTACIÓN METASTÁSICA INFRECUENTE DE ADENOCARCINOMA DE PULMÓN.
Authors: Sáez-Cazallas Rodríguez Carlos , Sáez Carlin Patricia
Published: September 2023

Las metástasis cutáneas o letálides dermis constituyen una afectación metastásica cuya aparición es extremadamente infrecuente, presentando una incidencia entre el 0,7-0,9% de los pacientes con tumores sólidos1