bluuebunny/crossref_metadata_2025 huggingface dataset:
MORPHOMETRICAL CHANGES IN THE RATS UTERUS THICKNESS AFTER 30 DAYS OF HEAVY METAL SALTS EXPOSURE
Authors: Sikora Kateryna
Published: February 2023

Introduction. Much attention is paid to the global ecological problem of environmental pollution with heavy metals (HM), starting from their production and use and ending with the search for means of their degassing and bioremediation. Particular attention is drawn to the study of the influence of HM on the reproductive system, in particular, the uterus. This is due to the high risk of reproductive ability deterioration and the reflection of the consequences of HM exposure in future generations.
Objective. The objective of our study was to perform morphometric measurement of the structural elements of the uterine wall in female rats under the conditions of 30-day exposure to HM salts, as well as to study the protective role of vitamin E.
Materials and Methods. For the experimental study, 24 female rats were selected and randomly divided into three series (8 rats in each): series I included control rats that received ordinary drinking water; series II included rats that daily consumed water saturated with HM salts; and series III included rats that were administered vitamin E orally every day against the background of constant consumption of water enriched with a combination of HM. After 30 days of the experiment, the uteri were removed; the sections were stained with hematoxylin and eosin for microscopic examination, followed by morphometric measurement of the structural elements and their statistical analysis.
Results. First, we measured the morphometric dimensions of the structural elements of the uterine wall in the control animals. At the same time, in the animals of the experimental series II and III, the morphometric indicators underwent significant changes. Thus, on the 30th day of the study, series II rats showed a significant thickening of the uterine wall by 31.03% (p < 0.001) vs. the indicators of the control series. A similar trend of morphometric changes in the thickness of the uterus was noted in series III animals, where the uterus thickened by 20.58% (p < 0.001). Moreover, a significant difference was also observed between experimental series II and III. The analysis of the organ structural components in the experimental series indicated the predominance of endometrium thickness over myometrium thickness.
Сonclusions. The results showed that 30-day exposure to HM led to a statistically significant thickening of the uterine wall. At the same time, the most pronounced changes in morphometric indicators were observed in the endometrium (in comparison with the myometrium and perimetrium) of both experimental models, both under the conditions of HM combination exposure and during the prophylactic use of vitamin E against the background of the action of xenobiotics. It is important to note that with the use of vitamin E, the morphometric indicators of the uterine thickness were characterized by a less pronounced transformation of values, although they still significantly exceeded the values of the control series.
FEATURES OF SUPERFICIAL VEIN THROMBOSIS IN PATIENTS WITH A LARGE DIAMETER OF GREAT SAPHENOUS VEIN
Authors: Mishura Viktoriia , Melekhovets Yurii
Published: February 2023

Introduction. Superficial vein thrombosis is characterized by the formation of thrombi in the superficial veins with subocclusion or occlusion of the venous lumen and its inflammatory reaction, which occurs more often in the lower extremities. Chronic venous disease in 75–88% of cases is the most important clinically identified factor in the development of superficial vein thrombosis. The great saphenous vein is affected in 60–80% of cases. A population-based study found that the chronic venous disease is a risk factor for venous thromboembolism and correlates with an increased risk of mortality in patients. Venous thromboembolism is a major burden of the disease worldwide, with approximately 10 000 000 cases per year.
Objective: to assess the prevalence of superficial vein thrombosis in patients with chronic venous disease and to identify the relationship between the diameter of the great saphenous vein and superficial vein thrombosis.
Materials and methods. Total of 925 chronic venous disease cases were analyzed from January 2019 to December 2021 at the Clinical Department of Surgery, Traumatology, Orthopedics, and Phthisiology of Sumy State University (Sumy Laser Clinic, LLC) for the prevalence of superficial vein thrombosis in patients with chronic venous disease who were undergoing treatment. The patients with superficial vein thrombosis were examined for the diameters of great saphenous vein and venous reflux using ultrasound 10 mm below the sapheno-femoral junction, in the upper and lower thirds of the thigh.
Results: Of 925 chronic venous disease cases, superficial vein thrombosis was observed in 53 cases, which accounted for 5.73 % of the total. Women accounted for 67.9 % (36), men – for 32.1 % (17). The study included patients aged 25 to 69 years (mean age 52.62 ± 10.48 years). In 69.8 % (37) of superficial vein thrombosis cases, the diameter of great saphenous vein was ≥ 10 mm at a level 10 mm below the sapheno-femoral junction; in 49 % (26) of cases – in the upper third of the thigh; in 30.2 % (16) of cases – in the lower third of the thigh. That is, the extension of the sapheno-femoral junction trunk to the lower third of the thigh was preserved in 43.24% of cases.
Conclusion. The results of the study revealed a high prevalence (5.73%) of superficial vein thrombosis. 69.8% of all cases of superficial vein thrombosis was registered in patients with a large diameter (≥ 10 mm) of great saphenous vein.
Works of the brothers N. and G. Volk-Karachevsky as a source from the history of the Zemstvo Liberal Movement in the North of the Left-bank of Ukraine (60-80th ХІХ сentury)
Authors: Kotelnytskyi N.A.
Published: February 2023

The article analyzes the creative heritage of members of the opposition aristocratic front of northern Ukraine – the works of the brothers N. and G. Volk-Karachevsky, the absolute majority of which are being introduced to international scientific circulation for the first time. The author comes to the conclusion that the discovered set of works of the brothers N. and G. Volk-Karachevskyi is a unique primary source from the history of the Zemstvo liberal movement in the north of Left Bank Ukraine (60-80s of the 19th century). The main issues of N. Volk-Karachevskyi’s works were the development of public education and the progress of agriculture. Nikodym Nikodymovych insisted on the priority free education of the poorest strata of the population – the peasantry, especially former serfs. In the field of agricultural production, the well-known liberal advocated the imperatives of urgent irrigation of the land fund of the Russian Empire, the formation of a purposeful strategy of Zemstvo institutes to improve the economic situation of the peasantry, the introduction of the positions of Zemstvo agronomists and technicians with appropriate official status and financial support, a strategic reference point for the perspective of the union of the peasantry, the liberal nobility and democratic intelligentsia in the struggle against the regime of Russian absolutism. The small number of publications by N. Volk-Karachevskyi were devoted to the problems of the development of the agricultural industry, which were little known at that time. The oppositionist insisted on the need to borrow the progressive experience of the countries of Western Europe, such as France, where a powerful system of agricultural education was built: from primary and higher education institutions to specialized scientific institutions. It is necessary to note separately the manifestation of the national enzyme in the journalism of the authors. Articulated allusions to the history of the statehood of the so-called Little Russia – the imperial name of a part of Ukrainian ethnic lands; their past economic and industrial glory; careful, but transparent wishes regarding the use of the dominant language in the territory of northern Ukraine, clearly indicate that the ethnic component occupied not the last place in the programmatics of the researched current of the liberation movement in the Russian Empire of the second half of the 19th century. In general, the discovered works of the brothers N. and G. Volk-Karachevsky clearly reflect the social program of the Zemstvo liberal party of the Northern Left Bank and illustrate the political and ideological imperatives of the opposition aristocratic front of the region.
Bioactive Flavonoids: A Comparative Overview of the Biogenetic and
Chemical Synthesis Approach
Authors: Gupta Mukta , Mishra Awanish
Published: February 2023

Flavonoids are natural polyphenolic compounds and constitute a major class of plant secondary
metabolites. To date, structures of more than 10,000 different flavonoids have been elucidated,
and most of them are present in cells and tissues of plant parts. Flavonoids have been reported to exert
multiple physiological activities and are also consumed as dietary supplements. Flavonoids have been
extensively explored as anticancer, anti-inflammatory, antidiabetic, antirheumatic, antioxidant, antimalarial,
neuroprotective, cardioprotective, anti-angiogenic, and antiproliferative agents. Most of the
flavonoids are biosynthesized in plants via the phenylpropanoid pathway. However, they are associated
with some limitations. Chemical synthesis is an alternative strategy to improve the yield and obtain
purified products but is hampered by drawbacks, such as intolerance to stressful lab conditions. Pharmacokinetics
is the rate-limiting step defining the bioavailability and metabolism of flavonoids, though
greatly influenced by their chemical structure. However, nanoformulation is an emerging technique
to improve biopharmaceutical fate and achieve target drug delivery. Thus, much attention should be
given to identifying other possible chemical approaches for synthesizing flavonoids and improving
their pharmacokinetic profiling, hence potentiating their efficacy in clinic.
Advances and Prospects in Antimicrobial Research using Nanomedicines
Authors: Agrawal Surendra S. , Nagendran Saraswathy , Pimpale Avdhoot
Published: February 2023

Background:

Nanotechnology is moving toward future goals in the field of medicines,
cosmetics and hospitality due to the size reduction of material in the range of 1-100nm, enhancing the
stability and bioavailability of the material.

Objective:

This review includes the progress in the field of nanotechnology, its advantages, understanding
and applications in antimicrobial therapy.

Methods:

The manuscripts were collected in the field of antimicrobial research with the help of nanotechnology
platforms from different sources like PubMed, ScienceDirect and Google. A total of 236
manuscripts were collected and analyzed, out of which 93 were relevant and considered for the present
manuscript.

Results:

There are diverse forms of metallic nanomaterials that show antimicrobial properties, such as
gold, silver, copper, zinc, titanium and many such metal oxides. Various carriers are used to deliver
the drug at targeted sites via encapsulating the nanomaterial in polymers, liposomes or in the lipoidal
structure. The inhibition of microorganism growth may be attributed to different mechanisms like destroying
the synthesis of a cell wall, nucleic acid, injury to the bacteria cell wall and inhibiting the
metabolic pathways in bacteria. This enhanced the antimicrobial activity and reduced the toxicity that
could be significant due to a reduction in the dose proportionality.

Conclusion:

The recent advances in drug delivery with the help of liposomes, solid lipid nanoparticles,
dendrimers, and various nanoparticles led to effective prevention, treatment and diagnosis of various
microbial infections and this could dramatically change the way antimicrobial therapy explored
for reducing drug resistance.
Role of Education and Physical Activity in Executive Function Performance
of Adult Population
Authors: Sharma Namrata , Shenoy Shweta
Published: February 2023

Background:

Executive function performance has been extensively studied in extreme
age groups, but the middle age population, where a decline could begin, is still under investigation.
The role of factors like education and physical activity that might influence cognitive performance
is not well understood.

Objective:

The study aimed to examine the influence of age, education, and physical activity on
executive function performance and the interaction effects between these factors on two subpopulations
of adults, i.e., young adults and middle-aged adults.

Methods:

92 adults, 46 young adults (N = 24.4 ± 2.7 years, 25 postgraduates and 21 PhDs) and 46
middle-aged adults (N = 48.08 ± 5.79 years, 28 postgraduates and 18 PhDs), were included. Each
subject performed Delayed Matching of Sample (DMS), Spatial Working Memory (SWM), and
Multitasking (MTT) test on CANTAB. Physical activity levels were reported through IPAQ.

Results:

Results indicated age to have a major influence on DMS, SWM, and MTT performance;
however, education was only found to influence SWM. MTT and SWM performance was found to
be lower in middle-aged adults in comparison to young adults. On comparison of test scores between
highly active and moderately active groups of middle-aged adults, no differences were
found; however, in young adults, MTT correct scores (p < 0.05) were significantly higher in the
highly active group in comparison to their counterparts. Interaction between age and level of education
revealed better retrieval in middle-aged adults with higher education in comparison to their
counterparts.

Conclusion:

In comparison to younger counterparts, executive function performance deteriorated
around the middle ages. Education was found to play a protective role in executive abilities slowing
during middle age. Also, physical activity may play some role in executive function performance.
Magnetic Spinel Ferrite Nanoparticles: From Synthesis to Biomedical Applications
Authors: Nikolic M.V.
Published: February 2023

Spinel ferrites are a widely investigated and applied class of materials with a cubic spinel lattice structure. Their unique multifunctional properties (magnetic characteristics, tunable shape/size, large number of active surface sites, high values of specific surface area, good chemical stability, and possibilities for enhancing properties through surface modification) influenced by the synthesis procedure make them attractive for biomedical applications as magnetic nanoparticles in drug delivery to a set target, magnetic hyperthermia, tissue engineering, magnetic extraction of biological components and magnetic diagnostics. In this review, we give an overview of up-to-date synthesis procedures for obtaining magnetic spinel nanoparticles and nanocomposites with optimal properties for biomedical applications.
Electromagnetic Properties of Cobalt Ferrite (CoFe2O4) with and without Addition of Niobium Pentoxide
Authors: Carvalho F.E.
Published: February 2023

This chapter compares the electromagnetic behavior of CoFe2O4 with and without addition of Nb2O5 in order to find biomedical applications of these compositions. Taking into account that their electromagnetic behavior is affected by their morphological structure, a structural analysis of samples prepared with different stoichiometries and sintered at different temperatures was performed. The formation of a new phase and the presence of lamellar veins crystallographically oriented by their magnetic domains were identified. In addition, complex measurements of electrical permittivity and magnetic permeability allowed us to infer that maximum absorption frequency increases with the addition of niobium pentoxide, while hysteresis cycles indicated a decrease in saturation magnetization and an increase in coercive force.
COMPARISON OF HYDRODISSECTION INJECTION THERAPY USING ULTRASONOGRAPHIC AS GUIDES BETWEEN TRIAMCINOLONE ACETONIDE AND 5% DEXTROSE IN CARPAL TUNNEL SYNDROME
Authors: Mardi Santoso Widodo , Sedar Wasis Sasono Ika , Ari Setianto Catur , Hevy Nuretha
Published: February 2023

Background: Carpal Tunnel Syndrome (CTS) is a symptomatic compression neuropathy of the median nerve characterized by increased pressure in the carpal tunnel and decreased nerve function due to compression of the median nerve in the carpal tunnel. The purpose of the hydrodissection injection method in CTS is to separate the soft tissue adhesions that cause nerve compression and this method are known for being minimally invasive, fast healing, and easy to apply. Local injection of triamcinolone acetonide (TCA) is often used as therapy for CTS because it stabilizes the sodium channels and reduces abnormal stimulatio, thus it relieved the pain. 5% dextrose injection (D5W) is also widely used as therapy of CTS because it is harmless to nerves and may reduce neurogenic inflammation through inhibition of capsaicin-sensitive receptors. Aim: To compare the effectivity of hydrodissection injection therapy using ultrasound guidance with triamcinolone acetonide and 5% dextrose in CTS. Methods: This study recruited 30 participants who diagnosed with CTS and met the inclusion criteria. Participants were divided into two treatment groups, the first group (n=15) was given 1ml TCA injection and 1 ml lidocaine 2%, while the second group (n=15) was given 5% 5 ml Dextrose injection. The parameters measured in this study were NRS, FSS, and SSS value before injection and 4 weeks after injection of the agent. We compared these parameters at week four after injection between the TCA group and the D5W group. Results: NRS values before and 4 weeks after TCA injection (sig 0.001; p <0.05), FSS values (sig 0.020; p <0.05), and SSS values (sig 0.001; p <0.05). NRS before and 4 weeks after injection of D5W (sig 0.002; p <0.05), FSS (sig 0.001; p <0.05), and SSS (sig 0.000; p <0.05). Comparison between TCA injection and D5W injection at 4 weeks after the injection showed that the results was significantly different on NRS (sig 0.806; p> 0.05) for FSS (sig 0.512; p> 0.05) and SSS (sig 0.293; p> 0.05). Conclusion: There is a significant difference in NRS, FSS and SSS values at 4 weeks after hydrodissection injection, using either TCA or D5W. TCA hydrodissection injection compared to D5W hydrodissection injection was equally effective in improving NRS, FSS and SSS after 4 weeks of injection.
La historia de la filosofía española, latinoamericana y mexicana como filosofía sin más
Authors: López Forjas Manuel
Published: February 2023

En este artículo se presenta una lectura personal sobre la temática en torno al problema de la filosofía en España, Latinoamérica y México, ofreciendo un acercamiento a textos específicos de María Zambrano, José Gaos, Leopoldo Zea y Carmen Rovira. El artículo tiene en cuenta el contexto histórico en el que escribieron los textos trabajados y comenta críticamente la posibilidad de tejer un hilo conductor en el camino que han trazado. Al final del texto, se ofrece a los lectores el enlace y la transcripción de la intervención de Carmen Rovira Gaspar en el programa de radio de la unam El ser y el pronóstico del tiempo, acerca de ¿Qué distingue a la filosofía mexicana? Se han colocado algunas notas que permiten explicar mejor a los autores y los textos a los que se hizo alusión.
Re-examining the center of gravity
Authors: Šlebir Miha
Published: February 2023

The center of gravity concept is one of contemporary military science’s fundamental yet highly controversial pillars. Although, over the past decades, the center of gravity has become the modus operandi of the planning and conduct of (major) military operations in a number of armed forces, the concept remains insufficiently understood and is often poorly applied in practice. In this light, we have sought to improve its theoretical comprehension by identifying the conceptual dimensions that the most influential authors commonly highlight. Using the structural method for the concept analysis, we have identified seven entities frequently understood as the potential centers of gravity. These are: (1) fielded military, (2) leadership, (3) industry, (4) infrastructure, (5) population, (6) public opinion, and (7) ideology.
Experiences of Using a Telepresence Robot During the COVID-19 Pandemic
Authors: Diaby Lahila Fanta , Dinesen Birthe
Published: February 2023

Background

School absenteeism due to mental disorders and physical disabilities is an international problem. When children are absent from primary school, they do not receive the fundamental educational foundation they are entitled to. This affects their further opportunities to receive higher education later in their life. Studies show that telepresence robots can include absent students in the teachings and social life at school.

Objective

The purpose of this project was therefore to investigate the opportunities and limitations of using an OriHime telepresence robot to teach absent primary school students during the COVID-19 pandemic.

Methods

This project was a case study from a primary school in Denmark. The study included primary school students (n=3), teachers (n=5), parents (n=2), a school principal, a pedagogue, a school absentee consultant, and a psychologist. The 14 participants were interviewed based on interview guides. In all, 20 hours of observation of OriHime have been made in the classroom conducting in the pilot test. Afterward, OriHime was tested by an absent primary school student for a 2-month period during the COVID-19 pandemic.

Results

The absent students found that OriHime was useful and a good alternative for them to be able to attend class. Teachers and pupils found that OriHime was useful in a class setting but not when conducting outdoor activities. The parents found that OriHime could include the absent students in the teachings and social life in class.

Conclusions

The absent students experienced that OriHime could function as an educational and social tool during COVID-19 and that it was possible to participate in the indoor teachings while being physically absent. The absent students, teachers, and parents found OriHime useful with opportunities but stated some limitations. Based on the results, a guideline for the implementation of OriHime in Danish primary schools was produced.

Conflicts of Interest

None declared.
A Digital Single-Session Intervention Platform for Youth Mental Health: Cultural Adaptation, Evaluation, and Dissemination
Authors: Shroff Akash , Roulston Chantelle , Fassler Julia , Dierschke Nicole A , Todd Jennifer San Pedro , Ríos-Herrera Ámbar , Plastino Kristen A , Schleider Jessica Lee
Published: February 2023

Background

Despite the proliferation of evidence-based digital mental health programs for young people, their low uptake and inconsistent implementation preclude them from benefiting youths at scale. Identifying effective implementation strategies for evidence-based supports is especially critical in regions where treatment access is lowest owing to mental health provider shortages.

Objective

The goal of this academic-community partnership, funded by the City of San Antonio Metropolitan Health District, was to culturally adapt, disseminate, and gauge the acceptability and utility of an evidence-based digital mental health platform—Project Youth Empowerment and Support (YES)—among English- and Spanish-speaking youths living in south Texas.

Methods

Project YES is an open-access, anonymous platform containing 3 evidence-based, self-guided interventions for youth mental health. Project YES was culturally adapted via focus groups and co-design sessions with San Antonio youths with lived experience of depression and anxiety; translated into Spanish; and disseminated throughout San Antonio, Texas, via community and school partnerships.

Results

During the project period (April 2021 to December 2021), 1801 San Antonio youths began and 894 (49.64%) of them completed a 30-minute, single-session intervention within Project YES (aged 11-17 years; n=718, 39.87% male; n=961, 53.36% female; and n=3, 0.17% intersex; n=1477, 82.01% Hispanic; n=77, 4.28% non-Hispanic White; n=113, 6.27% Black; n=28, 1.55% Asian; and n=93, 5.16% other). This completion rate (49.64%) surpassed those previously observed for Project YES (eg, 34% when disseminated via social media). San Antonio youths rated Project YES as highly acceptable across all metrics, both in English and Spanish. In addition, the youths who completed Project YES—ENGLISH reported significant improvements in hopelessness (Cohen d=0.33; P<001), self-hate (Cohen d=0.27; P<001), and perceived agency (Cohen d=0.25; P<001) from before to after the intervention, and the youths who completed Project YES—SPANISH reported significant improvements in self-hate (Cohen d=0.37; P=.049) from before to after the intervention.

Conclusions

The results indicate that Project YES—an open-access, free, and anonymous web-based single-session intervention platform—is an acceptable, accessible, and applicable mental health support for English- and Spanish-speaking San Antonio youths.
Effects of Physical Exercise on Telomere Length in Healthy Adults: Systematic Review, Meta-Analysis, and Meta-Regression (Preprint)
Authors: Sánchez-González Juan Luis , Sánchez-Rodríguez Juan Luis , Varela-Rodríguez Sergio , González-Sarmiento Rogelio , Rivera-Picón Cristina , Juárez-Vela Raúl , Tejada-Garrido Clara Isabel , Martín-Vallejo Javier , Navarro-López Víctor
Published: February 2023

BACKGROUND

Physical exercise is one of the main nonpharmacological treatments for most pathologies. In addition, physical exercise is beneficial in the prevention of various diseases. The impact of physical exercise has been widely studied; however, existing meta-analyses have included diverse and heterogeneous samples. Therefore, to our knowledge, this is the first meta-analysis to evaluate the impact of different physical exercise modalities on telomere length in healthy populations.

OBJECTIVE

In this review, we aimed to determine the effect of physical exercise on telomere length in a healthy population through a meta-analysis of randomized controlled trials.

METHODS

A systematic review with meta-analysis and meta-regression of the published literature on the impact of physical exercise on telomere length in a healthy population was performed. PubMed, Cochrane Library, SCOPUS, Web of Science, and Embase databases were searched for eligible studies. Methodological quality was evaluated using the Risk Of Bias In Nonrandomized Studies of Interventions and the risk-of-bias tool for randomized trials. Finally, the certainty of our findings (closeness of the estimated effect to the true effect) was evaluated using Grading of Recommendations, Assessment, Development, and Evaluations (GRADE).

RESULTS

We included 9 trials that met the inclusion criteria with fair methodological quality. Random-effects model analysis was used to quantify the difference in telomere length between the exercise and sham groups. Meta-analysis showed that exercise did not significantly increase telomere length compared with the control intervention (mean difference=0.0058, 95% CI −0.05 to 0.06; P=.83). Subgroup analysis suggested that high-intensity interventional exercise significantly increased telomere length compared with the control intervention in healthy individuals (mean difference=0.15, 95% CI 0.03-0.26; P=.01). Furthermore, 56% of the studies had a high risk of bias. Certainty was graded from low to very low for most of the outcomes.

CONCLUSIONS

The findings of this systematic review and meta-analysis suggest that high-intensity interval training seems to have a positive effect on telomere length compared with other types of exercise such as resistance training or aerobic exercise in a healthy population.

CLINICALTRIAL

PROSPERO CRD42022364518; http://tinyurl.com/4fwb85ff
Access to the Internet and Mobile Applications in a Mixed Population Emergency Department: A Repeated Cross-Sectional Survey (Preprint)
Authors: Toohey Shannon , Nguyen Michelle Thao , Saadat Soheil , Chandwani Carrie , Gassner Stephen , Wray Alisa , Rivera Ronald , Wiechmann Warren
Published: February 2023

BACKGROUND

Electronic media can be used to help address the communication gaps that exist between doctors and patients. Prior to utilizing these tools within an emergency department with patients of various socioeconomic statuses, it was important to collect data regarding patient accessibility to the internet, email, and other health management applications.

OBJECTIVE

The survey was conducted in 2014 and repeated in 2019 to identify trends in patients’ access to and use of the internet. We sought to assess the degree of interest in education content delivered through electronic modalities.

METHODS

This anonymous, prospective, cross-sectional survey included 50 questions and was completed by 241 English and Spanish-speaking patients in 2014. 253 additional surveys were collected in 2019. Participants were surveyed at the University of California, Irvine Medical Center’s Emergency Department (UCIMCED) while patients were waiting for treatment and diagnostic tests. The primary outcome was to compare internet access and communication technology use between 2014 and 2019. Secondary goal was to compare the pattern of internet use and search for health information between 2014 and 2019 among patients who presented to the UC Irvine Emergency Department.

RESULTS

The vast majority of patients have access to the internet, with 83.8% (N=241, 95%, CI: 78.5% - 88.2%) having access in 2014, and this number increasing to 88.1% (N= 253, 95%, CI: 83.5% - 91.9%) in 2019 (P=.160). Most internet-using patients owned a smartphone in 2014 (N= 161; 80.1%), increasing almost 10% by 2019 (N=200; 89.7%). When searching for health-related information, 32.5% of patients could always find pertinent health information and 20.6% found this information always reliable. In addition, patients reported using electronic devices to obtain more information on their health, including Fitbits, activity trackers, and blood pressure cuffs. Among a range of electronic modalities patients can use to communicate with their healthcare provider, patients felt most comfortable receiving discharge instructions via email in 2014 and 2019.

CONCLUSIONS

The implications of this study can be used to develop electronic resources tailored to educate emergency department patients about their healthcare beyond the confines of a hospital. Given that as of 2019 88.1% of patients in our emergency department have access to the internet or email, electronic media is a reasonable venue for patient education. Given that we have a predominantly low-income patient population, with 61% of respondents reporting an income of less than $25,000, these results are valuable and provide new ways to reach patients of all socioeconomic statuses.
Interactive Digital Self-management Interventions for Chronic Respiratory Disease: Systematic Review and Meta-analysis (Preprint)
Authors: Michaelchuk Wade , Quach Shirley , Benoit Adam , Maybank Aline , Oliveira Ana , Goldstein Roger , Brooks Dina
Published: February 2023

BACKGROUND

Interactive, digital self-management (IDSM) interventions may help individuals with chronic respiratory disease manage their condition.

OBJECTIVE

The aim of this review was to summarize the characteristics and effectiveness of IDSM interventions for individuals with chronic respiratory diseases.

METHODS

Reviewers screened titles, abstracts, and full texts of studies featuring: 1) applications or wearable devices for IDSM, 2) randomized controlled trials, and 3) adults with chronic respiratory disease. Articles were excluded if they were not available in English, French, or Portuguese. Study and intervention characteristics and outcomes were extracted. A meta-analysis was conducted for outcomes with combinable data.

RESULTS

The search generated 93,419 studies. Twenty-four trials were included in the qualitative synthesis and 17 in the quantitative synthesis. Studies evaluated 1726 individuals with asthma and 1265 individuals with chronic obstructive pulmonary disease (COPD; FEV1 %predicted 36 to 69). In asthma, median (range) intervention length was 12 (8-52) weeks. In COPD, median (range) intervention length was 24 (2-48) weeks. Meta-analysis for COPD studies showed IDSM interventions had a greater effect than control for health status (COPD Assessment Test score mean difference [95%CI]: -2.7 [-4.3, -1.2], P < .01) and physical activity (steps per day: 627.65 [95%CI 104.23, 1151.06], P = .02). Meta-analysis for asthma studies examined asthma control. No effect greater was found for asthma control test (0.55 [95% CI -1.90, 3.00], P = .66) or asthma control questionnaire (2.80 [95% CI -0.08, 0.64], P = .12). Evidence quality ranged from very low to moderate.

CONCLUSIONS

This review outlined the effectiveness and characteristics of IDSM interventions for chronic respiratory disease. Interventions were heterogeneous and studies yielded very low to moderate quality evidence. For COPD, IDSM benefitted health status and physical activity. Improvements in design of IDSM interventions will assist clinicians to identify those best suited to improve health in individuals with respiratory conditions.
Correction: The Effect of an App-Based Home Exercise Program on Self-reported Pain Intensity in Unspecific and Degenerative Back Pain: Pragmatic Open-label Randomized Controlled Trial (Preprint)
Authors: Weise Hannes , Zenner Benedikt , Schmiedchen Bettina , Benning Leo , Bulitta Michael , Schmitz Daniel , Weise Kuno
Published: February 2023

UNSTRUCTURED

Addendum to the Acknowledgements is attached as a file.
Religiusitas Versus Dukungan Sosial: Manakah yang Lebih Berkontribusi Bagi Well-Being Mahasiswa?
Authors: Wardoyo Jason Theosebya , Aditya Yonathan
Published: February 2023

Pandemi yang terjadi di berbagai negara di dunia, termasuk di Indonesia memberikan dampak negatif terhadap well-being mahasiswa. Hal ini membuat faktor-faktor yang dapat mempengaruhi well-being mahasiswa menjadi penting diteliti. Penelitian sebelumnya menemukan bahwa dimensi belonging dari religiositas memiliki pengaruh yang dominan terhadap well-being. Penelitian lain menemukan dukungan sosial juga berpengaruh positif terhadap well-being. Belonging dan dukungan sosial merupakan konstruk yang mirip. Oleh karena itu, peneliti ingin melihat bagaimana dinamika kaitan religiositas dan dukungan sosial terhadap well-being pada mahasiswa. Hasil regresi linier berganda dari data 216 partisipan menunjukkan religiositas dan dukungan sosial memberikan kontribusi terhadap well-being mahasiswa sebesar 28% (R2 = .28). Jika dilihat secara total, religiositas mempunyai kontribusi lebih besar (β = .33, ρ < .01) terhadap well-being dibandingkan dukungan sosial (β = .31, ρ < .01). Namun jika dilihat dari dimensi religiositas, dukungan sosial memiliki kontribusi yang lebih besar, dan hanya dimensi belonging yang signifikan. Hasil yang terlihat paradoks ini dan implikasinya akan dijelaskan.
Policy Reflection and Demystify on Street Vendors in the Context of COVID-19—Based on the Empirical Investigation of Pingfang District in Harbin
Authors: Yan Minna , Zhao Yike , Haomiao Yang
Published: February 2023

At the beginning of 2020, the epidemic raged in China. Faced with the great pressure of economic downturn, the state has issued policies to relax the limitations on the street vending economy, making it promote employment and maintaining social stability in the stage of economic restart and recovery. This paper discussed policies related to street vendor economy under the background of epidemic in Pingfang District and gave reasonable suggestions for the orderly and stable development of the vendor economy in the post-epidemic era.
The Impact of the Revision of Income Standards on the New Energy Vehicle Industry—A Case Study of BYD
Authors: Zhao Yixue
Published: February 2023

The rapid development of economy requires more and more energy. With the continuous enhancement of the awareness of environment and sustainable development, new energy has the advantages of low pollution and wide development prospects, and has been deeply studied by various countries. At the same time, in order to regulate the development of the new energy automobile industry, China revised the accounting standards for Business Enterprises No. 14 - revenue in 2017 to standardize the relevant measurement methods, which has a certain impact on the new energy automobile industry. Taking the development status and trend of China's new energy automobile industry in recent years as the research background, this paper uses the case analysis method and selects BYD, a new energy automobile company, as the research sample to systematically analyze the impact of the revision of the income accounting standards on the accounting, strategy and risk management of BYD, and puts forward targeted suggestions and measures for the effective implementation of the income accounting standards in the new energy automobile industry.
Intrinsic Competencies: A Leverage Tool for The Performance of Learning Organization (Case Study: Wasit University)
Authors: R. Alsreiwe Saad , A. Younis Joumana , Massoud Mazen
Published: February 2023

Learning organization performance is based on the sharing of experience and knowledge. The methods and adaptability of learners demonstrate its competitive advantage. However, in a fluctuating context marked by successive crises (economic, health), relying on intrinsic competencies is a crucial advantage for learning companies. This study investigated the influence of intrinsic competencies with three dimensions on the performance of the learning organization. This quantitative study used the questionnaire as a quantifiable tool to obtain data. A pre-test and face validation ensured the questionnaire’s validity. The analytical method is used in this study. Path analysis and SEM were applied in this study to test hypotheses. The influence of intrinsic competencies dimensions (Organizational Resources, Human Resources Strategies, Employees Capabilities) on the performance of learning organizations is the most prominent conclusion. The learning organization should adopt a learning and teaching culture where people collaborate and think together to constantly improves to enhance their performance.
Effects of water salinization on tomato seedlings (Solanum lycopersicum)
Authors: Oliveira Leandra Brito de , Oliveira Luziléa Brito de
Published: February 2023

Tomato quality is directly related to the quality of the water used for irrigation and the adequate supply of nutrients, which can lead to damage due to soil salinization, with a consequent reduction in crop yield. This work aims to evaluate the emergence and initial development of 'Bartô' tomato seeds when submitted to different levels of saline water. Tomato cultivar seeds (Solanum lycopersicum) were subjected to five concentrations of sodium chloride (NaCl), 2.5; 3.5; 4.5; 6.5 and 7.5 dS m-1. The design used was completely randomized (DIC) with four replications of 25 seeds per modality. Sowing was carried out in petri dishes, on a paper towel disc. The papers were moistened with the saline solution in their respective concentrations. Then the plates were sealed to prevent moisture loss. The assays were kept in the BOD (biology oxygen demand), at a temperature of 25ºC. In addition to the electrical conductivity test, the physiological characterization of tomato seeds was carried out, such as: first germination assembly, emergence speed index (IVE); germination percentage; seedling length. The data were submitted to analysis of variance using the SISVAR Software, and were not transformed, as they followed a normal and homogeneous distribution. The maximum salinity in irrigation water that tomato plants can withstand without affecting productivity was 1.7 dS m-1. The salinity level that negatively affected the studied variables was from 4.5 dSm-¹.
Coffee Storage in Hermetic Bags and its Influence on Prices and Sensory Scores
Authors: Zurita Carlos Alejandro , Foster Kenneth , Baributsa Dieudonne , Parra Carlos Alberto , Donovan Natalie
Published: February 2023

Coffee quality is generally evaluated through cupping, a technique based on sensory perceptions. Trained cuppers assign scores to ten quality attributes on a scale of 1 to 10. Exposure of coffee to moisture and/or oxygen during storage and/or transportation can affect the sensory evaluation and reduce the price received by farmers. This paper has two objectives. First, it estimates the effect of sensory scores and water activity on coffee price and its price differential from the market price. Second, it explores coffee sensory scores sensitivity to storage duration and water activity under two methods of application of the Purdue Improved Crop Storage (PICS) bags - the standard three layers PICS bag (PICS-3L) and the two layers PICS bag (PICS-2L). Data were collected for ten months from an experiment conducted in Manizales, Colombia. Results suggest, on average, that an additional point in the score of flavor or body increases the price of coffee by at least 66 COP/kg (0.015 USD/kg). If coffee has an additional point in aftertaste or uniformity from what is expected from other coffees of the same origin, then its price differential is reduced by at least 8 COP/kg (0.002 USD/kg). Using a PICS-3L bag instead of a PICS-2L bag does not affect the coffee price or sensory scores, but it reduces the price differential by approximately 18 COP/kg (0.004 USD/kg). On the other hand, water activity reduces coffee price but not its price differential. Storage time affects coffee sensory scores in some attributes, which may impact the coffee bean price.
Determinants of nitrogen use efficiency in coffee crops. A review
Authors: Sadeghian-Khalajabadi Siavosh , Acuña-Zornosa José-Ricardo , Salazar-Gutiérrez Luis-Fernando , Rey-Sandoval Juan-Camilo
Published: February 2023

World production of coffee (Coffea spp.) has increased in recent decades due to its growing demand. Nitrogen (N) is one of the most required nutrients by coffee crops and in many cases, the most yield-limiting; nevertheless, a high percentage of supplied N is lost, generating pollution, greenhouse gases, and economic losses. Given this scenario, it is a priority to adopt practices that increase nitrogen use efficiency related to the capacity of plants to absorb and use N to produce biomass. This article provides context about NUE and determining factors in coffee: plant, soil, climate, and management. On the plant side, despite advances in genetics and the results of genotype evaluation, it may be a decade or more before improved coffee varieties with high EUN become available or used in world coffee farming. Both the physical, chemical, and biological properties of the soil and the elements of the climate, mainly temperature, precipitation, and solar radiation, have an influence on coffee growth and many of the processes that intervene in the N cycle and NUE; however, some components of these two factors are not fully controllable. Management of the factors that determine NUE should focus on reducing N losses in the system, increasing its uptake and utilization by plants, and maintaining or increasing productivity.
Cattle movement as a function of some biotic and abiotic factors in a tropical pasture
Authors: Castilla Anderson Leonardo , Mora-Delgado Jairo , Rodríguez-Márquez Miguel , Lopez Jaime
Published: February 2023

The research question is how do some biotic and abiotic variables, under a silvopastoral system exert influence on the animal movement? These studies have been carried out through different approaches and have included analyses from empirical to statistical. The aim of this study was to relate cattle grazing sites with some biotic and abiotic factors under a silvopastoral system. The fieldwork was carried out in a paddock of the farm La Reforma located in the upper part of the Magdalena River basin (Tolima, Colombia). Through global positioning devices (GPS), movement, grazing route, and resting data that cattle perform in these habitats during daytime hours were obtained. Six cows (460 kg live weight, not pregnant) were monitored during two periods of the year at one-minute time intervals. Data were processed in a geographic information systems (GIS) environment, and mechanisms and algorithms were used to establish an association of moving animals with some biotic (pasture productivity and cover, trees, and floristic composition) and abiotic factors (climatological season, access to drinking and salt troughs). The results suggest an association between animal movement concerning the different attractants for which the drinking and salt troughs in the paddocks were relevant. In conclusion, the analysis of animal behavior at the landscape level is useful for decision-making in the design of livestock landscapes.
Хот төлөвлөлтийн үзэл баримтлалуудын хотын тэлэлтийг багасгахад үзүүлэх нөлөөллийг орон зайн зарим үзүүлэлтүүдийг ашиглан тооцох нь
Authors: Болормаа Б. , Fürst Christine , Буяндэлгэр М.
Published: February 2023

One of the most serious problems in the 21st century is urban sprawl. Due to that, many cities in the world today are facing the problem of chaotic settlement, traffic congestion, inadequate buildings and air pollution apart from that it has created settlement on floods, swamps, landslide and hazardous zone. Although the general land use planning of Ulaanbaatar city, is estimated to be 33698 hectares, which is suitable for the population of the settlement area, because of population increase the urban sprawl, it has reached to 39235 hectares as of today, exceeding 5,537 hectares. Although many urban development concepts are suggested to use in Ulaanbaatar, it is difficult to choose urban concept due to the lack of measurement and analysis of the city as a whole for each of the spatial indicators in the current situation and planning. In a specific urban setting, the most important step in performing this task is to evaluate current situation and compare planning results. In this study, the urban sprawl of Ulaanbaatar started in the 1990s, was determined by using geographic information system based on the satellite data of 1990, 1995, 2000, 2005 Landsat TM- 5, 2010 Quickbird, 2015 World View, and the March 2020 Sentinel2. This study measures the urban sprawl of Ulaanbaatar with spatial indicators and compares the urban development concepts with land use efficiency and land use form, and researches the issue of reducing urban sprawl by increasing the city's internal density. According to the study, the implementation of compact city concept of land readjustment on 4604 hectares will allow to improve the land use form by reducing the sprawl of the settlement threefold, and increase the efficiency of land use by allocating the settlements in 12479 hectares.
Баян (Увсын) нуурын хотгорын гарал үүсэл, морфологийн хэв шинжийн тайлал
Authors: Алтанболд Э. , Уламбадрах Х. , Гансүх Я. , Даариймаа Б. , Амаасүрэн Э.
Published: February 2023

Data on the origin and morphology of the lakes in Mongolia is relatively scarce. This study represents the relationship between lake depression and faults of the Lake Bayan in Uvs province, Mongolia. The volume and area of the lake are formed due to geological and geomorphological processes and climate change. Geological faults may relate to the lake's depression. whereas, the lake depression along faults have not been studied yet. The methods used in this study are morphometric methods (Analysis of topography, geomorphological criteria, hypsometric integral (HI) and Relief Slope (RSl) analysis), Spatial improvement method of remote sensing and, geophysical magnetic survey. The present morphological patterns of lake depression were defined by coherent research methods. The study result suggests that a fault has a significant impact on the origin of the lake depression. The main fault was formed in the western part of the Lake Bayan depression. Field investigation based on coherent methods, the fault influenced the origin of the lake depression, directed by the fault SW to NE. The length of the main fault is 82.5 km; 4 lakes have been formed along this fault. The largest of the Lake Bayan. The current research suggests that the Lake Bayan origin is different from the previous explanation, and the depressions of the lakes in Mongolia need to be redefined further.