bluuebunny/crossref_metadata_2025 huggingface dataset:
Sağlık Turizmi Farkındalığı: Malatya İlinde Sağlık Çalışanları Üzerine Bir Araştırma
Authors: ŞAHİN Münevver , YILMAZ Mustafa , KARAMUSTAFA Kurtuluş
Published: December 2023

Bu araştırmanın temel amacı sağlık çalışanlarının sağlık turizmi konusunda farkındalık düzeylerini ve sağlık turizmi farkındalığının demografik değişkenlere göre ne derece farklılaştığını belirlemektir. Bu amaç doğrultusunda, kolayda örnekleme yöntemiyle Mayıs 2022'de Malatya ilinde faaliyet gösteren bir kamu hastanesinde görev yapan 350 sağlık çalışanından anket uygulaması ile veri elde edilmiştir. Yapılan istatistiki analizler sonucunda sağlık çalışanlarının genel anlamda sağlık turizmi farkındalığının orta düzeyde olduğu (3,40/5,00) tespit edilmiştir. Ek olarak, sağlık çalışanlarının sağlık turizmi farkındalığının incelenen cinsiyet, yaş, öğrenim durumu, meslekteki geçirilen yıl, çalışılan birim ve gelir düzeyi değişkenlerine göre istatistiksel olarak anlamlı şekilde farklılaştığı tespit edilmiştir. Erkek çalışanların ve lise mezunlarının farkındalığının yüksek olduğu, 39-45 yaş aralığındaki çalışanların sağlık turizminin sorunları hakkında daha bilinçli olduğu, hastane yönetiminde çalışan personelin farkındalığının yüksek olduğu ve en fazla beş yıldır görev yapmakta olan çalışanların diğerlerine göre sağlık turizmi konusunda daha bilinçli oldukları sonucuna ulaşılmıştır. Çalışma sonuçlarına göre sağlık kurumu yöneticilerine ve gelecek çalışmalara önerilerde bulunulmuştur.
Eğitim Haberlerine Gazetelerin İnternet Sayfalarında Nasıl Yer Verildiğine İlişkin Bir Çözümleme
Authors: AYDOĞDU Nilgün , URAL Ayhan
Published: December 2023

Bu çalışmanın amacı, Türkiye’de yayınlanan, basılı günlük ulusal gazetelerin internet sayfalarında eğitim haberlerine nasıl yer verildiğine ilişkin bir çözümleme yapmaktır. Bu doğrultuda; eğitim haberlerinin biçimsel olarak internet sayfalarında konumlandırıldıkları yere (ana sayfa, alt başlık ve hiç yer verilmeme), eğitim haberlerinin konularına (öğretmen, öğrenci, sınav, resmi kurumlar vb.) ve eğitim haberlerinin içeriklerinin nasıl verildiğine (doğrudan aktarım, eleştirel, duyuru vb.) ilişkin bir çözümleme yapılmıştır. Araştırmada nitel araştırma modellerinden biri olan doküman çözümlemesi kullanılmıştır. Araştırmanın veri kaynağını, Türkiye'de 2023 yılı Mart ayı içerisinde yayınlanan yirmi iki, basılı günlük ulusal gazetenin resmi internet sayfası oluşturmaktadır. Araştırmada amaçlı örnekleme yöntemlerinden ölçüt örnekleme yöntemi kullanılmıştır. Araştırmada nitel veri analiz türlerinden betimsel analiz kullanılmıştır. Kodlama sürecinde ise kategorik çözümleme tekniği kullanılmıştır. Araştırma sonuçları genel olarak değerlendirildiğinde; yirmi iki gazetenin eğitime birinde ana sayfada, onaltısında alt başlıklarda yer verildiği, beşinde ise eğitime hiç yer verilmediği görülmüştür. Eğitim haberlerinin internet sayfalarında konumlandırılmasından hareketle yapılan bu çalışmada eğitim haberlerine hem ulaşma pratiğinde hem de içerik analizleri açısından değerlendirildiğinde; biçimsel olarak eğitim haberlerine ulaşmak için alt başlıklarda arama yapılması gerektiği sonucuna varılmıştır. Ayrıca incelemeye konu gazetelerin neredeyse tamamında eğitimin gelişmesi ve kamu yararı sağlayacak şekilde bir köşe yazısı, yazı dizisi veya eğitim yazarlarının yazılarının olduğu bir yazarlar başlığına yer verilmediği görülmüştür. Bu sonuçlar, günlük ulusal gazetelerin internet sayfalarında eğitim konusuna etkili bir şekilde yer verilmediğini göstermektedir.
Estimation of hematological parameters and lipid profile of coronary artery disease patients with Helicobacter pylori
Authors: Alhasan Muntadher , Manal Badi Salih
Published: December 2023

Helicobacter pylori infection causes generally gastric illnesses, however from the beginning of 1994, a few researchers have detailed a relationship of H. pylori with other systemic manifestations are outside stomach include various extra gastric appearances, for e.g., neurological, dermatological, hematologic, visual, cardiovascular, metabolic, hypersensitive, and hepatobiliary diseases. In this study, blood parameters, lipid profile, and fasting glucose were measured for patients with coronary artery disease with H. pylori, and the relationship of H. pylori with lipids, which is considered a risk factor for coronary artery disease, was measured. 150 people participated in the current study, and they were divided into three groups: The first group had arterial disease. coronary artery disease with H. pylori 50 people, the second group had coronary artery disease without H. pylori 50 people, the third group the control group 50 people. The samples were obtained from the heart center in Nasiriyah. Risk factors were taken into account: which included age, gender, smoking status, high blood pressure, and diabetes. In the first group, the number of males was 28 (56%) and females 22 (44%) with an average age of 72.60 ± 18.97, the second group had a number of males 33 (66%) and females 17 (34%) with an average age of 71.70 ± 21.06, the third group the number of males was 28 (56%) and females 22 (44%) with an average age of 55.44 ± 18.53.
Untangling the complex food webs of tropical rainforest streams
Authors: Saito Victor , Kratina Pavel , Barbosa Gedimar , Ferreira Fabio , Leal Jean , Zemelka Gabriela , Sarmento Hugo , Perkins Daniel
Published: December 2023

1- Describing food webs with precision and detail is critical for understanding the functioning of ecosystems. Streams in the Brazilian Atlantic Rainforest stand out as one of the most threatened ecosystems worldwide and yet, little is known about whether these systems house stable food webs and what are the trophic properties associated with that. 2 - In this study, we applied a Bayesian Hierarchical approach unifying three sources of information (gut content analysis, literature compilation, stable isotope data) to derive a well-resolved meta food web and five individual food webs from an Atlantic Forest catchment in Brazil. Together with data on population-level biomass and individually measured body mass, we applied a bioenergetic model and assessed their dynamical stability using a Lotka-Volterra approach. From the meta food web, we simulated individual population extinctions and their impacts on the food web stability. Finally, we calculated network dissimilarity indices in order to estimate the relative importance of regional processes for the maintenance of the meta food web.3 - The hierarchical model resulted in a meta food web with 307 probable links among the 65 components, from basal resources to consumers (aquatic insects, shrimps, and fish). At the regional scale, a surprisingly large proportion of total energy flow (70%) occurred through a set of ten invertebrates with large variation in body masses, from chironomids to shrimps. The remaining 30% of total energy flow relied on 51 different taxa supporting a significant dependency on a diverse community.4 - We found that these food webs were robust against disturbances, with dynamic resilience of the bioenergetic models. The simulations of population extinctions resulted in scenarios with stable food webs indicating that these systems do not rely strongly on keystone species for their resilience. Finally, approximately 40% of the interactions changed among local food webs mostly due the absence of predators in individual streams.5 - At the local scale, stability was likely maintained due to the high diversity of organisms with different body-sizes buffering against size specific disturbances. At the regional scale, high total diversity should entail the colonization of redundant taxa at a high rate, while high beta diversity of predators should enhance spatial asynchrony and regional stability. Here we integrated for the first time a hierarchical model to rebuild a detailed food web with methods for estimating energy fluxes within it. This innovative approach provides a baseline for the structure and functioning of tropical rainforest streams, setting the ground for future studies on how these ecosystems may respond to environmental change.
Políticas educativas para la igualdad en educación superior: becas PRONABES desde las representaciones sociales de los beneficiarios
Authors: Morales Vanegas Elizeth , Valles Ruíz Rosa María
Published: December 2023

Hablar de programas de becas es hablar de política educativa, en México, el PRONABES (Programa Nacional de Becas) fue creado en el año 2001, en el marco del Programa Nacional de Educación 2001-2006 del Gobierno federal, en un Ejecutivo de cambio partidista con el mandato de Vicente Fox Quesada. El principal propósito que tiene es generar condiciones de igualdad a una mayor cantidad de jóvenes en la Educación Superior que tienen problemas económicos. Este programa muestra diferentes formas de reportar sus resultados y alcances con resultados de ejercicios evaluativos y mediante la utilización de información de corte estadístico, esto también como parte de la rendición de cuentas, sin embargo se tiene escasa información desde los beneficiarios directos sobre las condiciones de igualdad que busca generar este programa con el apoyo económico que otorga y aún en menor medida, sobre las mejoras o implicaciones prácticas en pro de mejorar dichas condiciones. La presente ponencia pretende explicar cómo atender esta dimensión desde los becarios y que se deriva del protocolo de investigación trabajado durante el primer semestre del programa educativo de la Maestría en Ciencias Sociales de la UAEH y del cual se desarrollará el trabajo de tesis para la obtención de grado, el cual se centrará en las construcciones sociales y aprensiones (significaciones y resignificaciones) individuales sobre las condiciones de igualdad educativa desde la postura de becario PRONABES. Para el abordaje del objeto de estudio se considera pertinente la utilización de los principios teóricos y metodológicos de las Representaciones Sociales.
The potential impact of policies and structural interventions in reducing cardiovascular disease and mortality: a systematic review of simulation-based studies
Authors: Uthman Olalekan A , Court Rachel , Anjorin Seun , Enderby Jodie , Al-Khudairy Lena , Nduka Chidozie , Mistry Hema , Melendez-Torres G J , Taylor-Phillips Sian , Clarke Aileen
Published: December 2023

Background

The aim of the study was to investigate the potential effect of different structural interventions for preventing cardiovascular disease.

Methods

Medline and EMBASE were searched for peer-reviewed simulation-based studies of structural interventions for prevention of cardiovascular disease. We performed a systematic narrative synthesis.

Results

A total of 54 studies met the inclusion criteria. Diet, nutrition, tobacco and alcohol control and other programmes are among the policy simulation models explored. Food tax and subsidies, healthy food and lifestyles policies, palm oil tax, processed meat tax, reduction in ultra-processed foods, supplementary nutrition assistance programmes, stricter food policy and subsidised community-supported agriculture were among the diet and nutrition initiatives. Initiatives to reduce tobacco and alcohol use included a smoking ban, a national tobacco control initiative and a tax on alcohol. Others included the NHS Health Check, WHO 25 × 25 and air quality management policy.

Future work and limitations

There is significant heterogeneity in simulation models, making comparisons of output data impossible. While policy interventions typically include a variety of strategies, none of the models considered possible interrelationships between multiple policies or potential interactions. Research that investigates dose–response interactions between numerous modifications as well as longer-term clinical outcomes can help us better understand the potential impact of policy-level interventions.

Conclusions

The reviewed studies underscore the potential of structural interventions in addressing cardiovascular diseases. Notably, interventions in areas such as diet, tobacco, and alcohol control demonstrate a prospective decrease in cardiovascular incidents. However, to realize the full potential of such interventions, there is a pressing need for models that consider the interplay and cumulative impacts of multiple policies. Rigorous research into holistic and interconnected interventions will pave the way for more effective policy strategies in the future.

Study registration

The study is registered as PROSPERO CRD42019154836.

Funding

This article presents independent research funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment programme as award number 17/148/05.
Nature-based interventions to support mental health and well-being of young women in pregnancy: exploratory work for future feasibility RCT
Authors: Sands Gina , Blake Holly , Carter Tim , Spiby Helen
Published: December 2023

Background

The prevalence of mental health and well-being issues among young women is increasing. Pregnancy is a time when new mental health challenges may arise, or existing conditions can be exacerbated. This project presents preparatory work on how nature-based interventions may help to support the mental health and well-being of young pregnant women (aged 16–24 years) in a future study.

Methods

This project was formed of three main phases conducted from March to August 2022: (1) mapping nature activities available across the East Midlands region and two focus groups with providers of nature activities (n = 6); (2) public participation and involvement work to inform future research. This included four focus groups with young women (n = 11), leading to the formation of a new young women’s panel (Research Influencers Group). Networking and stakeholder engagement to support future research.

Results

The mapping survey identified 68 nature-based organisations/projects operating in the region, many of whom expressed interest in being involved in future research. The young women’s focus groups confirmed the importance of the topic and generated a wealth of information to support the intervention design. A Research Influencer Group of five young women was established from the focus group participants. The Research Influencer Group chose the nature-based intervention and had input into all aspects of the study design. This group will continue into future projects. Focus groups with providers of nature activities have further advanced the study design. The project team have developed relationships with relevant stakeholders and networks that will inform the future trial.

Conclusion

This preparatory co-design work suggested that a nature-based intervention may be acceptable to young women, and providers of such interventions felt it was feasible to offer these activities to young pregnant women. This preparatory work has led to an outline research plan which has been co-produced with public contributors and stakeholders throughout.

Limitations

This preparatory work is limited by small focus group samples, and the possibility that not all providers were reached through the snowballing approach to the mapping survey.

Future work

Future research is needed to test the nature-based intervention; this would be in the form of a feasibility randomised controlled trial of nature-based interventions to promote the mental health and well-being of young pregnant women.

Funding

This article presents independent research funded by the National Institute for Health and Care Research (NIHR) Public Health Research programme as award number NIHR135167.
Ensuring the competitiveness of the hospitality industry enterprises
Authors: Fedyshyn I. , Boiko A.
Published: December 2023

The article discusses theoretical concepts, essence and features of ensuring the competitiveness of hospitality industry enterprises. Authors analyzed trends in the development of the hotel and restaurant business in the period 2020-2022. In particular, it was determined that the crisis conditions of the pandemic had a negative impact on the number of restaurants in Ukraine. Also, changes in the political and economic environment of recent times have greatly affected the way companies operate. The shift from a production economy to a market economy and globalization have put companies in front of new realities. In 2019, there were 48,398 of them, and in 2020, this number decreased to 41,139. In other words, 7,259 restaurants ceased operations, which is 15% of the level of 2019 and even less than in 2018. In 2020, the number of business entities operating in the accommodation and catering sector in Ukraine reached a maximum of more than 7,700. In 2021, the figure decreased to 69,800 accommodation and catering companies. Since the beginning of the war in Ukraine, about 7000 restaurants and cafes have closed, and more than 2000 new food establishments have opened. The hospitality industry market decreased by about 25% compared to February 2022. In some regions, the market decline was more than 50% (Kharkiv, Mykolaiv, Zaporizhzhia, Luhansk regions), and in Kyiv, Odesa, and Dnipro regions - up to 30%. The western regions showed positive dynamics in 2022. In particular, the number of restaurants and cafes increased by about 30% in Lviv and its region, and by about 20% in Zakarpattia, Chernivtsi, and Ivano-Frankivsk regions. The patterns of development of restaurant business enterprises in Ukraine were characterized by both positive and negative factors. The article presents basic proposals for improving the competitiveness of hospitality industry enterprises in modern realities.
Study of export and import turnover of the regional development of the national economy by the method of clustering objects in the context of European integration processes
Authors: Harmatii S.
Published: December 2023

The European course of development of the national economy, which was taken back in 2014, is undergoing certain stages of transformation. At the first stages of European integration, a number of transformational transitions took place from partnership from the "Eastern" direction to a clear vector towards EU countries and global partnership. The Ukrainian production system was morally and technologically outdated a long time ago. New external factors, such as Covid-19, introduced their transformational changes in management and the transition to "digitalization" of both production and information and management flows. The study of the potential of export-oriented regions of Ukraine will allow to determine priorities in the introduction and implementation of European standards and requirements, such as for production, compliance with European requirements for product quality, environmental requirements, and other aspects, the standards of which are prescribed in the road map of Ukraine's accession to the EU, and, accordingly, European integration processes for all enterprises and companies of the national economy. The external aggression of the Russian Federation in 2022 only accelerated the processes of European integration transformations for the sectors of the national economy, the products of which are primarily exported to EU countries and the world. Such goods include products of the agro-industrial sector, mineral products, wood and wood products. And if agro and food products make up 53% of the total export in Ukraine in 2022, the share of metallurgy is only 4.3%. In our article, we investigated which sectors of the economy are a priority for the support of state and European institutions and financial foundations, for further dynamic development and investment and economic support. Also, in our article, we conducted research and modeling of the regions of Ukraine, which are the largest clusters in terms of export and import turnover. Such research using modern scientific methods of cluster analysis will allow to unite the regions of Ukraine in one cluster according to the level of export and import turnover. This will allow identifying the potentials in the regions of the lower clusters and increase their potential opportunities in the future to develop those sectors of the national economy that will be able to ensure the growth of export-oriented products. The development of the metallurgical sector of the national economy and military-oriented production will allow not only to increase the defense capability of our country, but also to increase the share of export-oriented products, and accordingly to significantly improve the production potential of the national economy. The use of modern Python-type software in our article allows you to visualize all the performed stages of modeling using cluster analysis.
STATE INSTITUTION «NATIONAL RESEARCH CENTER FOR RADIATION MEDICINE OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE» – RESEARCH ACTIVITIES AND SCIENTIFIC ADVANCE IN 2022
Authors:   State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», Bazyka D. , Sushko V. ,   State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», Chumak A. ,   State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», Fedirko P. ,   State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», Talko V. ,   State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», Yanovych L. ,   State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine»
Published: December 2023

Research activities and scientific advance achieved in 2022 at the State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine» (NRCRM) concerning medical problems of the Chornobyl disaster, radiation medicine, radiobiology, radiation hygiene and epidemiology in collaboration with the WHO network of medical preparedness and assistance in radiation accidents are outlined in the annual report. The report presents the results of fundamental and applied research works of the study of radiation effects and health effects of the Chornobyl accident. The report also shows the results of scientific-organizational and health care work, staff training. The Scientific Council meeting of NAMS approved the NRCRM Annual Report. Key words: NRCRM, Chornobyl, radiation effects, epidemiology, radiation hygiene, treatment of victims, international cooperation, personnel. Key words: NRCRM, Chornobyl, radiation effects, epidemiology, radiation hygiene, treatment of victims, international cooperation, personnel.
HEMATOPOIETIC PROGENITORS CELLS IN PERIPHERAL BLOOD OF BALB/C MICE UNDER IONIZING RADIATION ACTION IN SUBLETHAL DOSE
Authors:   National University of Kyiv-Mohyla Academy, Russu I. Z. , Bilko D. I. ,   National University of Kyiv-Mohyla Academy, Bilko N. M. ,   National University of Kyiv-Mohyla Academy
Published: December 2023

Objective: determination of the content of hematopoietic progenitor cells circulating in peripheral blood of Balb/C mice, under ionizing radiation action in sublethal dose, at different periods after the irradiation, using cell culture in diffusion chambers in vivo. Methods. Peripheral blood smears of Balb/C mice were prepared and studied, its cellular composition was determined, as well as by cultivation of peripheral blood cells in diffusion chambers in vivo their colony-forming efficiency was determined on the 0th, 5th, and 30th day after external irradiation in sublethal dose 5.85 Gy. Results. The content of myelocytes and metamyelocytes among blood nucleated cells of the irradiated animals was increased, compared to control, during the whole investigated period. In particular, on the 30th day after irradiation the content of myelocytes in peripheral blood was 3.3 ± 0.7 % compared to (0.8 ± 0.4) % in control, and the content of metamyelocytes – (3.4 ± 0.7) % compared to (0.9 ± 0.3) % in control. A significant increase in the amount of circulating progenitor cells in the peripheral blood was observed in the early stages after irradiation (12.5 ± 1.6 colony-forming units per 100,000 explanted cells, compared to 5.1 ± 0.8 in control). However, on the 5th day their content was slightly reduced compared to control (1.3 ± 0.9), and only to the 30th day a normalization of the amount of progenitor cells occurred in the peripheral blood (6.8 ± 0.7 colony-forming units per 100,000 explanted cells). Conclusions. The analysis of the obtained results revealed an increased level of immature forms of cells in the peripheral blood of irradiated animals, compared to control, in the early stages after irradiation, including hematopoietic progenitor cells, which are able to colony forming in cell culture. Therefore, the action of ionizing radiation in sublethal dose had a critical effect on the proliferation of hematopoietic cells in bone marrow and provoked their increased migration into the bloodstream. Determination of the content of hematopoietic cells’ immature forms in peripheral blood allowed assessing the degree of hematopoietic damage due to the action of ionizing radiation. Key words: hematopoiesis, circulating progenitor cells, ionizing radiation, sublethal dose, cell culture in vivo.
REVIEW OF THE NATURE OF ANTI-INFLAMMATORY AND PRO-INFLAMMATORY CYTOKINE REGULATION IN DIFFERENT PERIODS OF PLASMA CELL MYELOMA NATURAL HISTORY IN THE CHORNOBYL NPP ACCIDENT SURVIVORS
Authors:   State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», Minchenko Zh. M. , Dmytrenko O. O. ,   State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», Silaiev Yu. O. ,   State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», Liubarets T. F. ,   O.O. Bogomolets National Medical University
Published: December 2023

Objective: identify the nature of anti-inflammatory and pro-inflammatory cytokine regulation in different periods of plasma cell myeloma (PCM) natural history with evaluation of its role as a prognostic criterion for the disease course in the Chornobyl NPP (ChNPP) accident survivors. Materials and methods. Levels of pro-inflammatory (IL-6, TNF-α) and anti-inflammatory (IL-10) cytokines both with their relationship were studied in the stage I–II and stage III PCM patients (n = 74) in different periods of the disease natural history i.e. remission/stabilization and progression. Study groups included the ChNPP accident survivors (n = 35) and non-irradiated subjects (n = 39). Immunoenzymatic method was applied using the Vector-Best CJSC commercial kits. Results. There was a unidirectional increase in the levels of IL-6, TNF-α, and IL-10 in irradiated persons, and an elevation of IL-6 and TNF-α concentration but with a decreased level of IL-10 in non-irradiated subjects compared to control at the time of PCM diagnosis. Period of the disease remission/stabilization in PCM stage I–II patients featured a decrease in IL-6 concentration regardless of the exposure to ionizing radiation, while TNF-α content remained at the level of the control group. There was a significant increase in IL-6 concentration in both study groups during the disease relapse, while TNF-α level remained unchanged compared to stabilization phase of the disease. According to the obtained data a certain contribution of radiation exposure to the PCM pathogenesis as a possible predictor of the exacerbated disease course cannon be excluded. Conclusion. Determining the serum level of pro-inflammatory and anti-inflammatory cytokines (IL-6, TNF-α and IL-10 respectively) provides advancement in assessment of the PCM course and predict the effectiveness of administration of therapy protocols. Key words: plasma cell myeloma, anti-inflammatory cytokines, pro-inflammatory cytokines, Chornobyl NPP accident.
THE STRUCTURE OF THE INCIDENCE OF ONCOHEMATOLOGICAL DISEASES IN ECOLOGICALLY DISADVANTAGED REGIONS OF THE DNIPROPETROVSK REGION FOR THE PERIOD 2006–2017
Authors:   PI «Dnipropetrovsk City Multidisciplinary Clinical Hospital No. 4» DCC, Selina I. O. ,   Dnipro State Medical University, Dyagil I. S. ,   State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine»
Published: December 2023

Objective: to conduct a comparative analysis of the incidence of malignant oncohematological diseases structure among the population of the 4 most ecologically disadvantaged cities of the Dnipropetrovsk region, taking into account the possible influence of various adverse environmental factors (radiation and chemical pollution of air, water and soil) for the period 2006–2017. Materials and methods. 1948 cases of acute myeloblastic and lymphoblastic leukemia, chronic myeloid and lymphocytic leukemia in residents of 4 cities of the Dnipropetrovsk region were analyzed, taking into account the possible influence of adverse environmental factors (radiation, air pollution, etc.). We used clinical and hematological data per patient and statistic information on these diseasis incidence in the region. Results. An analysis of the oncohematological patients incidence structure, namely: acute lymphoblastic (C91.0) and myeloblastic leukemia (C92.0), chronic lymphocytic (C91.1) and myeloid (C92.1) leukemia, over 12 years in environmentally disadvantaged cities of Dnipropetrovsk region have been conducted. A comparative analysis of the incidence of these diseases among the population of 4 cities of the Dnipropetrovsk region was carried out, taking into account the possible influence of adverse environmental factors (radiation, air pollution, etc.). An excess of the incidence rates of the above-mentioned oncohematological diseases for the period 2006–2017 was revealed in the cities of Dnipro, Kryvyi Rih, Kamianske and Zhovti Vody, where environmental factors significantly affect the increase in morbidity due to pollution mainly by radioactive and chemical substances. Key words: morbidity, acute lymphoblastic leukemia, chronic lymphocytic leukemia, chronic myeloid leukemia, acute myeloid leukemia, environmental disadvantage, radiation.
ROLE OF CONTEMPORARY IMAGING METHODS IN RADIOTHERAPY PLANNING AND MONITORING OF GYNECOLOGICAL CANCER PATIENTS (REVIEW)
Authors:   National Cancer Institute of the Ministry of Health of Ukraine, Ivankova V. S. , Domina E. A. ,   R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of National Academy of Sciences of Ukraine, Khrulenko T. V. ,   National Cancer Institute of the Ministry of Health of Ukraine, Baranovska L. M. ,   National Cancer Institute of the Ministry of Health of Ukraine, Glavin O. A. ,   R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of National Academy of Sciences of Ukraine
Published: December 2023

Radiotherapy (RT) and radiation oncology are of essential role in the clinical treatment of cancer patients. The widely available imaging modalities such as diagnostic ultrasound, computer-assisted tomography, and contrastenhanced MRI are used in clinical practice for diagnostics and management planning. Moreover, these methods are also used to monitor the treatment upon RT. However, some diagnostic issues cannot be sufficiently resolved by the simple use of standard morphological imaging. Thus, positron emission tomography is gaining an increasing clinical relevance in the management of cancer patients undergoing RT, as it allows to visualize and quantify the tumor features at a molecular level, such as tumor metabolism or receptor expression, beyond simple morphological patterns shown by the conventional imaging. This review focuses on the recent and current advances in imaging techniques, including PET imaging, in the diagnostics and planning of RT in some cancers, namely in cervical cancer.
ACUTE RADIATION SICKNESS IN HUMAN: ETIOPATHOGENESIS, CLINIC, DIAGNOSIS AND TREATMENT (LECTURE)
Authors:   State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», Belyi D. , Sushko V. ,   State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine», Bazyka D. ,   State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine»
Published: December 2023

Under the conditions of war in Ukraine, there remains a high probability that russia will use nuclear weapons or commit terrorist acts against nuclear power plants, which will lead to exposure of the population in doses that cause acute radiation sickness (ARS). In this regard, our medical service must be ready for the treatment of ARS of various degrees of severity under a mass influx of victims. In peacetime, ARS is a rather infrequent pathology, so most doctors lack experience in its treatment. This article, having the form of a lecture, presents material on the pathogenesis, classification, clinic, diagnosis and treatment of ARS, taking into account the modern achievements of radiation medicine. Treatment of ARS is based on the use of pharmaceutical drugs that are licensed in Ukraine. The article will be useful for doctors and medical workers of all branches and levels of health care, who will have to deal with irradiated persons in order to timely identify patients with ARS and provide them with effective treatment. Key words: acute radiation sickness, bone marrow syndrome, oropharyngeal syndrome, hematopoietic growth factor, antibacterial therapy.
APPLICATIONS OF THREE DIMENSIONAL FACIAL COMPUTED TOMOGRAPHY IN HEAD AND NECK REGION – A REVIEW
Authors:   PSP Medical College Hospital and Research Institute, Shunmugavelu K. , Kannapan H. ,   Sree Balaji Medical College Hospital and Research Institute, Vaishnavi P. ,   Sri Venkateswara Dental College - Hospital, Dhinakaran E. C. ,   Sree Balaji Medical College Hospital and Research Institute, Lavanya S. ,   Malabar cancer centre, Kumar B. ,   Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital
Published: December 2023

3D facial CT has evolved and revolutionized diagnosis leading to better management. The limitations of conventional 2D methods limit the therapeutic options related to leading to an erroneous treatment. Although 3D facial CT is expensive, its advantages outweigh the cons. They are used in surgery, prosthetic replacement, orthodontics and forensics. Key words: 3D facial CT, prosthetic, orthodontics.
Mathematical substantiation and creation of information tools for optimal control of drilling and blasting in open-pit mine
Authors: Shcherbakov P , Tymchenko S , Moldabayev S , Amankulov M , Babets D
Published: December 2023

Purpose. To establish the rationale for the informational infrastructure necessary for effectively managing drilling and blasting operations in open-pit mining of rock deposits. To define the distribution function of natural rock blocks within the mass they comprise. To ensure timely access to data regarding the strength, fracturing characteristics of geological formations in their initial state, as well as the particle size distribution of mined materials obtained post-explosion. Methodology. Statistical modeling techniques were employed to analyze the natural blockiness of rock masses. The approach involved utilizing the principle of measuring the dimensions of individual rock fragments through a transmitting television tube and differentiating the obtained results using electronic pulse circuits. Electronic circuits capable of implementing statistical dependencies derived for drilling machines and loading excavators were introduced. Findings. Electronic devices have been proposed for real-time determination of the dimensions of natural rock blocks along their visible surfaces, as well as for assessing the strength, fracturing characteristics of rocks within the mass, and the particle size distribution of the mined material obtained during drilling and blasting operations. Originality. The study has established the distribution function of natural rock fragments within a mass, serving as a prototype for the distribution function of visible rock fragments located on the sidewall of a slope. The theoretical developments of the proposed electronic devices are protected by patents. Practical value. The presented tools for obtaining real-time, objective information about the natural blockiness, strength, and fracturing characteristics of rock formations in their initial state (before blasting), as well as relationship of these indicators with the particle size distribution of mined material obtained through blasting. These a tangible opportunity to implement optimal management of the entire blasting process, which will enable the enhancement of the technical and economic performance of open-pit mining
Problems of operating heating boilers of increased environmental efficiency
Authors: Fialko N. M , Navrodska R. O , Shevchuk S. I , Serhiienko R. V
Published: December 2023

Purpose. Ensuring reliable operation of heating heat-generating devices with recirculation and exhaust gas heat recovery. Methodology. The normative methods of thermal calculation for surface heat exchange devices and the software according to the requirements of regulatory methods for this type of equipment for processing the results of our own experimental studies on heat exchange during deep cooling of combustion products of gas-consuming boilers were used. Findings. Calculation studies on the thermal operation modes during the heating period under the conditions of recirculation and heat recovery of flue gases of gas-fired water-heating boiler plants not equipped with air heaters were carried out. The main characteristics were determined of the thermal and humidity operation state for the air-supply ducts of these installations under the conditions of recirculation of flue gases’ part into the blown air. Regularities of temperature and dew point changes in the mixture of admixed gases and air under the conditions of using traditional heat recovery technologies and without them in different boiler modes and with different parts of recirculated gases were established. Problems of ensuring the operability and reliability of such boiler plants are highlighted. It is shown that these problems are related to condensate formation on the internal surfaces of air ducts and their freezing in some operating modes during in the cold period of the heating season. It is also shown that an effective solution to existing problems can be the use of air heaters in heat recovery systems to preheat the blown air before its mixing with recirculation gases. Originality. For the first time, the thermal and humidity operation modes of the air-supply ducts of heating boiler plants with increased environmental efficiency, which is ensured by boiler exhaust gases recirculation into the blown air, have been investigated. Practical value. The obtained research results will be used in the design of systems of recirculation and heat recovery of heat-generating devices’ exhaust gases to improve their environmental and thermal efficiency.
Automated building damage detection on digital imagery using machine learning
Authors: Kashtan V. Yu , Hnatushenko V. V
Published: December 2023

Purpose. To develop an automated method based on machine learning for accurate detection of features of a damaged building on digital imagery. Methodology. This article presents an approach that employs a combination of unsupervised machine learning techniques, specifically Principal Component Analysis (PCA), K-means clustering, and Density-Based Spatial Clustering of Applications with Noise (DBSCAN), to identify building damage resulting from military conflicts. The PCA method is utilized to identify principal vectors representing the directions of maximum variance in the data. Subsequently, the K-means method is applied to cluster the feature vector space, with the predefined number of clusters reflecting the number of principal vectors. Each cluster represents a group of similar blocks of image differences, which helps to identify significant features associated with fractures. Finally, the DBSCAN method is employed to identify areas where points with similar characteristics are located. Subsequently, a binary fracture mask is generated, with pixels exceeding the threshold being identified as fractures. Findings. The introduced methodology attains an accuracy rate of 98.13 %, surpassing the performance of conventional methods such as DBSCAN, PCA, and K-means. Furthermore, the method exhibits a recall of 82.38 %, signifying its ability to effectively detect a substantial proportion of positive examples. Precision of 58.54 % underscores the methodology’s capability to minimize false positives. The F1 Score of 70.90 % demonstrates a well-balanced performance between precision and recall. Originality. DBSCAN, PCA and K-means methods have been further developed in the context of automated detection of building destruction in aerospace images. This allows us to significantly increase the accuracy and efficiency of monitoring territories, including those affected by the consequences of military aggression. Practical value. The results obtained can be used to improve automated monitoring systems for urban development and can also serve as the basis for the development of effective strategies for the restoration and reconstruction of damaged infrastructure.
Structuring “education – migration – labour market” chain
Authors: Barvinok V. Yu , Artyukhova N. O , Marci A , Polishchuk I. R , Vasylieva T. A
Published: December 2023

Purpose. This study aims at analysis of the research landscape with the current trends, gaps, and potential directions for future publications in education, migration, and labour markets in preventing “brain drain” in Ukraine during the war. Methodology. The research method is based on analysis of chronological nature of educational, migration and labour markets and building geographical, interconnections maps and utilizing Scopus and Web of Science databases within VOSviewer software. Findings. The comparison of subject areas demonstrated the interdisciplinary nature of the study, where “social sciences sector” (48.8 %), “economics, econometrics, and finance” (14.8 %) are leading in scientific literature. Four clusters and three clusters of scientific publications were determined in Scopus and Web of Science accordingly. The following trends were obtained: effect of migration on labour market outcome, economic opportunities of high-quality human capital, student professional development to avoid economic crisis were actively investigated by scientists, as well as crisis due to migration flow among young people at universities, positive effect of immigrants and connection with formal education. The highest number of relevant articles are in the United States, Germany, and the United Kingdom. The spatial analysis demonstrates intercontinental connection between researchers of six clusters (North American and Pacific countries, Countries of Northern Europe and the Middle East, Central European countries, island, and peninsular countries of the European contingent and the Gulf of Mexico, Central and Western European countries, Western European countries, and Intercontinental cluster). Ukrainian authors regularly collaborate with scientists from Poland, the Netherlands, France, Switzerland, and the United States. Originality. For the first time, a comprehensive analysis covering all three aspects (education, migration and the labor market) was conducted in order to study the interrelationships and mutual influence of these sectors of the economy. The analysis was carried out on geographical-chronological maps built by the authors based on the Scopus and Web of Science databases. Practical values. The results can be utilized to develop new strategies, policies, and legislative initiatives to ensure improve economical and organizational management of education at universities in a country.
Information support for management of energy-saving economic development of enterprises
Authors: Prokhorova V. V , Yemelyanov O. Yu , Koleshchuk O. Ya , Antonenko N. S , Zaitseva A. S
Published: December 2023

Purpose. Formation of theoretical and methodological approaches to structuring information provision and assessing its significance for achieving energy-saving economic development of enterprises. Methodology. In the research process, the following methods were used: economic-mathematical modeling, grouping, generalization, system analysis, etc. Findings. The conditions under which energy-saving economic development takes place at enterprises have been formalized. Methodological principles of quantitative and qualitative assessment of the level of such development are proposed. The array of information necessary for managing the energy-saving economic development of enterprises is structured. Based on a sample of 150 Ukrainian enterprises that consume natural gas, the level of energy-saving economic development is assessed. The importance of information management of this development is substantiated. Originality. The methods for grouping the types of economic development of the enterprise by highlighting a new classification characteristic, namely: the nature of the relationship between the change in the value of a certain financial and economic result of the enterprise’s activity and the change in its consumption of a certain type (types) of energy resources, have gained further development. Methodological principles for assessing the impact of the quality of information support on the performance of enterprises have been improved through the substantiation of the approach, which determines the impact of the completeness of information support for the management of energy-saving economic development of enterprises on its level. An approach to structuring an array of information for managing energy-saving economic development of enterprises is proposed, which, unlike the existing ones, involves taking into account the hierarchical nature of the array of data. Practical value. The obtained results can be used by enterprises when evaluating the dynamics of their economic results in comparison with changes in the amount of consumption of energy resources and when forming information support for the management of energy-saving economic development.
Sino-Caspian Energy Cooperation: an Analysis of Kazakhstan And Turkmenistan Cases
Authors: Nest R.
Published: December 2023

This paper analyses the current state of Sino-Caspian energy cooperation by examining China’s energy relationships with its two major economic partners in the region: Kazakhstan and Turkmenistan. China’s increasing energy demand over the past decades has led to significant investments and cooperation in these countries. Kazakhstan has become a vital trade partner, with China investing in its energy sector and becoming a significant importer of Kazakh oil. Similarly, Turkmenistan has seen China emerge as its primary economic partner due to its vast natural gas reserves. This paper concludes in both sections that despite challenges such as declining trade volumes and competition from other suppliers, China is poised to remain an important stakeholder for both Kazakhstan and Turkmenistan.

В данной статье анализируется текущее состояние энергетического сотрудничества Китая со странами Каспийского региона посредством изучения энергетических отношений Китая с двумя его основными экономическими партнёрами в регионе: Казахстаном и Туркменистаном. Растущий спрос Китая на энергию за последние десятилетия привёл к значительным инвестициям в эти страны и расширению сотрудничества с ними. Казахстан стал жизненно важным торговым партнёром Китая, который инвестировал в его энергетический сектор и стал крупным импортёром казахстанской нефти. Аналогичным образом, Туркменистан стал свидетелем того, как Китай стал его основным экономическим партнёром из-за его огромных запасов природного газа. В обоих разделах данной статьи делается вывод о том, что, несмотря на такие проблемы, как снижение объёмов торговли и конкуренция со стороны других поставщиков, Китай намерен оставаться важным партнёром как для Казахстана, так и для Туркменистана.