bluuebunny/crossref_metadata_2025 huggingface dataset:
Recommendation to improve the WHO classification of posterior pituitary tumors as a unique entity: evidence from a large case series
Authors: Qiao Nidan , Cheng Haixia , Zhang Zhaoyun , Ye Hongying , Shen Ming , Shou Xuefei , Cao Xiaoyun , Chen Hong , Zhou Xiang , Wang Yongfei , Zhao Yao
Published: May 2022

Introduction

Most studies reporting posterior pituitary tumors (PPTs) are small case series or single cases.

Methods

Patients with a histological diagnosis of PPT from January 2010 to December 2021 in a tertiary center were identified. We reported clinical symptoms, endocrine assessments, radiological and pathological features, and surgical outcomes of PPTs.

Results

A total of 51 patients (23 males, 51.3 ± 10.3 years old) with PPT were included in this study. Major symptoms were visual defects, headache, and hypopituitarism, while diabetes insipidus was uncommon (9.8%). The typical radiological feature was homogeneous enhancement (84.3%) of a regular-shaped mass on T1 contrast imaging without cystic change, calcification, or cavernous sinus invasion. We achieved gross total resection in 38/51 patients (74.5%). Pathologically, all tumors showed thyroid transcription factor 1 immunoreactivity. Among 29 patients with suprasellar PPTs, postoperative hemorrhage due to tumor residue was encountered in 2/15 cases in the transcranial group and 0/14 in the endoscopy group. Patients with spindle cell oncocytoma (SCO) were more likely to be surgically treated (25% vs 0%, P = 0.018), harbor a higher Ki-67 index (16.7% vs 0% > 5% P = 0.050), and present a lower 2-year recurrence-free survival rate (67.5% vs 90.9%) compared with patients with pituicytoma or granular cell tumor.

Conclusion

PPTs should be considered in the differential diagnosis of patients with sellar and suprasellar masses with a regular lesion with homogeneous enhancement. SCOs had high proliferation activity and risk of recurrence.
The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis
Authors: Gomez-Lopez Nardhy , Galaz Jose , Miller Derek , Farias-Jofre Marcelo , Liu Zhenjie , Arenas-Hernandez Marcia , Garcia-Flores Valeria , Shaffer Zachary , Greenberg Jonathan M , Theis Kevin R , Romero Roberto
Published: May 2022

In brief

The syndrome of preterm labor comprises multiple established and novel etiologies. This review summarizes the distinct immune mechanisms implicated in preterm labor and birth and highlights potential strategies for its prevention.

Preterm birth, the leading cause of neonatal morbidity and mortality worldwide, results from preterm labor, a syndrome that includes multiple etiologies. In this review, we have summarized the immune mechanisms implicated in intra-amniotic inflammation, the best-characterized cause of preterm labor and birth, as well as novel etiologies non-associated with intra-amniotic inflammation (i.e. formally known as idiopathic). While the intra-amniotic inflammatory responses driven by microbes (infection) or alarmins (sterile) have some overlap in the participating cellular and molecular processes, the distinct natures of these two conditions necessitate the implementation of specific approaches to prevent adverse pregnancy and neonatal outcomes. Intra-amniotic infection can be treated with the correct antibiotics, whereas sterile intra-amniotic inflammation could potentially be treated by administering a combination of anti-inflammatory drugs (e.g. betamethasone, inflammasome inhibitors, etc.). Recent evidence also supports the role of fetal T-cell activation as a newly described trigger for preterm labor and birth in a subset of cases diagnosed as idiopathic. Moreover, herein we also provide evidence of two maternally-driven immune mechanisms responsible for preterm births formerly considered to be idiopathic. First, the impairment of maternal Tregs can lead to preterm birth, likely due to the loss of immunosuppressive activity resulting in unleashed effector T-cell responses. Secondly, homeostatic macrophages were shown to be essential for maintaining pregnancy and promoting fetal development, and the adoptive transfer of homeostatic M2-polarized macrophages shows great promise for preventing inflammation-induced preterm birth. Collectively, in this review, we discuss the established and novel immune mechanisms responsible for preterm birth and highlight the potential targets for novel strategies aimed at preventing the multi-etiological syndrome of preterm labor leading to preterm birth.
Endoglin (CD105) as a putative prognostic biomarker for colorectal cancer: a systematic review
Authors: Sur Daniel , Havasi Andrei , Lungulescu Cristian Virgil , Volovat Simona Ruxandra , Burz Claudia , Irimie Alexandru
Published: May 2022

The outcome of colorectal cancer (CRC) can be improved by the identification of prognostic biomarkers. This systematic review of observational cohort and case-control studies was conducted to investigate the role of Endoglin (CD105) in the prognosis of CRC. The databases PubMed, Web of Science, Scopus, and Cochrane CENTRAL were searched to identify the qualified studies using the relevant keywords. After the removal of duplicate articles, the screening was implemented on the titles, abstracts, and potential full-text articles. Afterward, the eligible cohort and case-control studies were identified, and the data were extracted into an Excel datasheet. In total, 11 observational cohort studies and 1 case-control study were identified to be eligible for this systematic review. The majority of the included studies achieved a moderate to high-degree quality according to the Newcastle-Ottawa Scale. Moreover, the eligible studies included a total of 1,400 patients with CRC and mean age of 60 years, the majority of whom were male. Endoglin was observed to be more upregulated in colorectal carcinomas and associated with poor survival outcomes, compared to healthy controls. The levels of Endoglin seem to reflect the degree of cancer invasiveness, therefore predicting dismal prognosis in patients with CRC. Larger and well-designed clinical studies with longer follow-up intervals are needed to investigate the role of Endoglin and its association with cancer metastasis.
Determination of modafinil in rat plasma by UPLC-MS/MS and a study of its pharmacokinetics and bioavailability
Authors: He Yan , Ma Yizhe , Luo Lvqi , Chen Junying , Wen Congcong , Zhang Meiling
Published: May 2022

Modafinil has a strong and long-lasting awakening effect. Short-term use can improve cognitive and work efficiency. Therefore, it has been known to be abused by students and parents as a “smart drug.” It is in the first category of psychotropic drugs and strictly controlled. To detect modafinil in rat plasma and study the differences in the pharmacokinetics of modafinil between oral and sublingual administration in rats, an ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was developed. Rats were injected with modafinil by oral gavage and sublingual vein, respectively, blood was collected within a certain period, and the plasma was obtained by centrifugation. Midazolam was used as the internal standard, and the concentration of modafinil in the plasma was determined by UPLC-MS/MS, where a drug-time curve was created to calculate the pharmacokinetic parameters. The standard curve for modafinil ranged from 1 to 2000 ng mL−1 with good linearity. The intra-day accuracy of modafinil was between 86% and 104%, and the intra-day accuracy was between 90% and 103%. Intra-day precision (RSD%) was less than 15%, inter-day precision (RSD%) was less than 15%. The matrix effect was between 93% and 102%, and the recovery was greater than 91%. The UPLC-MS/MS method established in this work has good selectivity and high sensitivity, and the UPLC-MS/MS method was successfully applied to the pharmacokinetics of modafinil by oral gavage and sublingual injection in rats. The bioavailability of modafinil was calculated to be 55.8%.
Towards the copular status of clefts—Evidence from diachrony
Authors: Jin Dawei , Chen Jun
Published: May 2022

This paper draws attention to a robust grammatical change trajectory, here dubbed the copula-to-cleft pathway. We show that the emergence of the copular clause construction tends to lead to the emergence of the cleft construction, and the decline of one tends to be in tandem with the other. We further propose that the above pattern follows from a syntactic treatment that derives the cleft structure from a copular clause. Such copular syntax can be further combined with a semantic analysis where the focus interpretation of clefts is computed based on a copular structure.
Розробка автоматизованої системи дозування рідких продуктів
Authors: Голубєв Л. П. , Резніков С. А.
Published: May 2022

У статті виконано дослідження дозування рідких продуктів. У роботі харчових, текстильних та фасувальних підприємств операції дозування виконуються дуже часто. Тому проблема автоматизації цих операцій стоїть особливо гостро. Автоматизація дозування дозволяє вивільнити робітників для виконання інших операцій, забезпечити більш точне дозування продукту. Авторами розроблено новий підхід до виконання операції порційного дозування рідких продуктів. Він заснований на застосуванні для управління дозуванням мікропроцесорної системи, а як порційний датчик використаний тензодатчик, що забезпечує високу точність вимірювань. В якості мікропроцесорної системи була використана плата Arduino UNO. Розроблено макет автоматизованої системи дозування рідких продуктів. Проектування мікропроцесорної системи управління виконувалось за допомогою системи FlProg, яка дозволяє використовувати засоби візуального програмування, що суттєво прискорює та спрощує процес проектування. Перед початком роботи системи виконується калібрування тензодатчика, встановлення ваги в нульове положення та облік ваги тари. У процесі роботи здійснюється зважування порції рідини і, якщо досягнуто задане значення, припиняється її подача. Інформація про поточне значення ваги рідини, що дозується, і кількість виконаних дозувань відображається на LCD екрані. Розроблена система є універсальною – її можна використовувати для великого спектру рідин, що дозуються, а також, після невеликої доробки, і для сипких продуктів. Невелика вартість розробленої системи є її безперечною перевагою перед існуючими системами, що забезпечує можливість її використання на різних підприємствах (зокрема ФОП та МП).
Розробка асетів для комп’ютерної гри у жанрі RPG
Authors: Бойцова М. , Ломовцев П. Б. , Бойцова О. С.
Published: May 2022

У роботі розглянуто процес розробки асетів для комп’ютерних ігор за професійним пайплайном, етапи моделювання та текстурування, акцентовано увагу на технологіях OpenGL та PBR. В роботі пропонується оптимальне поєднання технологій та програмних засобів для створення якісного проекту для подальшого використання як унікальних ігрових об’єктів. Особливу увагу приділено питанню оптимізації моделей на етапі роботи з сіткою, розлянуто ряд автоматичних засобів і виконано порівняння в ефективності з ручними методами. З метою прискорення роботи та економії цифрових ресурсів виконується ряд технічних задач : виконання ретопології, розгортки моделей, запечення карт нормалей. Продемонстровано технології високоякісного рендерингу в реальному часі для створення фінальної демонстрації готових асетів.
Long-Term Development and Health of Children Conceived by Assisted Reproductive Technologies
Authors: Belyaeva Irina А. , Namazova-Baranova Leyla S. , Baranov Alexander A. , Efendieva Kamilla Y. , Karkashadze George A. , Dedyukina Elena S. , Serebryakova Elena N. , Konstantinidi Tatiana A. , Molodchenkov Alexey I. , Gogberashvili Tinatin Yu.
Published: May 2022

The demographic situation in Russia requires escalation of measures to combat infertility including assisted reproductive technologies (ART). The analysis of correlations between ART and features of health and long-term development of “children from the tube” is presented. There is a high risk of dysontogeny after in vitro fertilization/intracytoplasmic sperm injection due to epigenetic disorders such as DNA methylation disorders. Living conditions, parenting, education, and health care are crucial for the healthy development of all children including those conceived by ART. The correlations between long-term cognitive development of “children from the tube” and the aspects of parenting in families are presented.
Synthesis and luminescent properties of new tungstates Ln2Zr(WO4)5 (Ln = Tb, Dy)
Authors: Bazarov B. G. , Dorzhieva S. G. , Shendrik R. Y. , Tushinova Y. L. , Bazarova Ts. T. , Sofich D. O. , Chimitova O. D. , Bazarova J. G.
Published: May 2022

New polycrystalline powder samples of double Ln2Zr(WO4)5 (Ln = Dy, Tb) tungstates were synthesized using high-temperature solid-phase and sol-gel methods. The conditions of the sol-gel synthesis of tungstates were optimized. The obtained phases were characterized by the X-ray powder diffraction on the basis of the crystallographic data of similar Ln–Zr molybdates. It is found that Ln2Zr(WO4)5 (Ln = Dy, Tb) double tungstates crystallize in the orthorhombic crystal system, space group Cmc21 (Z = 4). The intensive luminescence in the green spectral region for Tb2Zr(WO4)5 and yellow spectral region for Dy2Zr(WO4)5 was shown.
AUTOVALORAÇÃO DE COMPETÊNCIAS GENÉRICAS EM EGRESSOS DE UM BACHARELADO INTERDISCIPLINAR BRASILEIRO
Authors: ARAÚJO FERNANDA RIBEIRO DE , FONTOURA CARLOS EDUARDO DA SILVA , CONTI WILLIAM REMO PEDROSO , MARTINS FERNANDO RAMOS , SCACHETTI RODOLFO EDUARDO , OLIVEIRA-MONTEIRO NANCY RAMACCIOTTI DE
Published: May 2022

RESUMO: As competências profissionais representam uma combinação de atributos (conhecimentos, habilidades e atitudes) que descrevem o grau em que a pessoa é capaz de desempenhá-los, podendo ser classificadas como: específicas (relacionadas diretamente com a profissão), e genéricas (transferíveis a múltiplas funções e tarefas). O estudo apresenta autoavaliações de competências genéricas feitas por egressos do Bacharelado Interdisciplinar em Ciência e Tecnologia do Mar, da Universidade Federal de São Paulo. Participaram da pesquisa 180 egressos formados de 2015 a 2018. Das 19 competências genéricas autovaloradas com maior desenvolvimento durante o curso, destacam-se Capacidade de trabalhar em equipe e Compromisso ético. Motivação para o trabalho, Capacidade de aplicar os conhecimentos à prática e Motivação para alcançar metas foram as menos valoradas. Para os egressos que estavam trabalhando, as competências tidas como mais importantes para o trabalho foram: Compromisso ético, Responsabilidade no trabalho e Capacidade de trabalhar em equipe. Conhecimentos básicos da profissão, Capacidade de aplicar os conhecimentos à prática e Motivação para o trabalho foram valoradas como menos importantes. Houve discrepâncias na valoração de competências entre o desenvolvido no curso e o praticado no trabalho, apontando um descompasso entre o desenvolvimento dessas competências na Universidade e o que é demandado no mercado profissional.
OUTRAS FORMAS DE PENSAR AS DOCÊNCIAS EM MATEMÁTICA: OS USOS DE TEORIA E PRÁTICA NA FORMAÇÃO DE PROFESSORES
Authors: BOFF DAIANE SCOPEL , FABRIS ELÍ TEREZINHA HENN
Published: May 2022

RESUMO: Este artigo desenvolve-se a partir das discursividades sobre teoria e prática que circulam na formação de professores. A pesquisa, ao tomar como inspiração analítica as teorizações de Michel Foucault, o pensamento tardio de Ludwig Wittgenstein e estudos sobre docência contemporânea, descreve os significados atribuídos à teoria e à prática em cursos de formação de professores de Matemática e analisa de que forma eles têm produzido docências que reforçam enunciados dicotômicos sobre essas dimensões. O material de pesquisa foi produzido a partir de entrevistas semiestruturadas com professores de Matemática que desenvolvem a docência em cursos de Licenciatura em Matemática no sul do país. O movimento analítico realizado mostra que, na docência em Matemática, ao significarem-se os conhecimentos matemáticos e pedagógicos somente em uma das dimensões, são construídos modos de ensinar que priorizam o que está na ordem do concreto e do cotidiano ou o que está na ordem da abstração e do formalismo, naturalizando e reforçando, na formação de professores, a dicotomização teoria-prática.
Quando o Estado não chega: a eficácia de programas educacionais em assentamentos, comunidades indígenas e quilombolas
Authors: LOBO CINARA ARAÚJO , BERNARDINO-COSTA JOAZE
Published: May 2022

RESUMO: O artigo avalia os benefícios efetivos da política de descentralização de recursos federais da educação para unidades de ensino situadas em comunidades indígenas, quilombolas e assentamentos. A partir da análise quantitativa de dados do Censo da Educação Básica, de informações de saldo e repasse de valores do Programa Dinheiro Direto na Escola e de dados da Federação da Indústria do Rio de Janeiro, relacionam-se o volume de recursos transferidos, a estrutura física das escolas e a capacidade estatal dos entes federados. A hipótese inicial é que comunidades historicamente excluídas se encontram situadas em municípios com baixa capacidade estatal e apresentam maior dificuldade em desenvolver políticas educacionais diferenciadas. O artigo também levanta a hipótese de racialização do Estado, que normaliza a precariedade das condições de existência das populações tradicionais. Conclui-se chamando atenção para a complexidade da execução de políticas descentralizadas para essas comunidades e a importância de se incluir, nas reflexões e avaliações, o papel do Estado racial.
DOMESTIC GYMNASTICS OF THE DOCTOR DANIEL SCHREBER: CIRCULATION MANUALS IN THE LAST DECADES OF THE XIX CENTURY
Authors: PUCHTA DIOGO RODRIGUES , LINHALES MEILY ASSBÚ
Published: May 2022

ABSTRACT: This study deals with the production and circulation processes of a manual entitled Ginástica doméstica, médica e higiênica ou representação e descrição de movimentos ginásticos, first published in Leipzig, in 1855, by the German physician Daniel Gottlob Moritz Schreber and addressed to parents and educators. Starting from a particular scale of observation that includes singularities that characterize the diffusion of the referred manual between the second half of the 19th century and the beginning of the 20th, we sought to identify the adopted authorship and editorial strategies, as well as the “manufacturing” exercises present in the various translations, in order to understand how printed texts confer and add effects of truths to certain knowledge about the body. More specifically, two translations of the work that circulated in Brazil are analyzed. The first was published in Lisbon, in 1879, and the second in Rio de Janeiro by the newspaper Gazeta de Notícias, in 1887. The study allows us to affirm that it was translations, as a strategy of appropriation and cultural circulation, that allowed tris work to achieve a remarkable achievement reach in different countries.
Por uma poética do instante. Roland Barthes em Haruo Ohara
Authors: Fontanari Rodrigo
Published: May 2022

Resumo Este ensaio busca explorar a poética da obra fotográfica do nipo-brasileiro Haruo Ohara. Particularmente, pretende-se estabelecer uma aproximação inesperada de suas fotografias com a concepção estética de Roland Barthes, elaborada pelo semiólogo notadamente a partir da publicação de O império dos signos, em 1970.
Exhibicionismos y borramientos en prácticas artísticas brasileñas de comienzos de los 80
Authors: Cóccaro Victoria
Published: May 2022

Resumen El presente artículo propone reflexionar sobre las maneras en que, en una serie de escrituras, intervenciones urbanas, performances y un libro-objeto que se produjeron en Brasil entre 1979 y 1982, los cuerpos adquirieron nuevas figuraciones y reaparecieron en el espacio público, antes vedado por la dictadura militar. En particular, se analizarán prosas de João Gilberto Noll, intervenciones urbanas del colectivo 3nós3, performances del Movimento Arte Pornô y un libro experimental de Hudinilson Urbano Jr. Partimos de la hipótesis de que en el contexto de los retornos democráticos estas prácticas artísticas están recorridas por dos fuerzas en tensión, borrosidades y exhibicionismos, a través de las cuales los cuerpos responden a la represión y la violencia, practican herencias alternativas, ensayan nuevos modos de visibilización y exploran nuevos vínculos entre el arte y la política.
Oito poemas de Jaime Gil de Biedma: A invenção de um personagem
Authors: Valladares Saturnino
Published: May 2022

Resumo Ao entender que sua obra poética estava terminada, o poeta espanhol Jaime Gil de Biedma titulou seu último livro como Poemas póstumos, em 1968. Entre outros motivos, o personagem poético reflete sobre a profunda crise de identidade que lhe provoca o final da juventude. Neste trabalho apresento minha versão ao português de oito poemas deste poemário.
Análise do comportamento mecânico de concreto com agregado reciclado e adição de fibras de aço e de vidro AR
Authors: Furian Bruna O. , Pimentel Lia L. , Forti Nádia C. S. , Jacintho Ana Elisabete P. G. A.
Published: May 2022

RESUMO A extensa utilização do concreto no mundo provoca a geração de grandes quantidades de resíduos, vinculada a sua produção e utilização. Hoje, esse resíduo é subestimado, porém em alguns países o seu uso como agregado reciclado é permitido na produção de novos concretos. Estudos apontam que o agregado reciclado no concreto pode diminuir algumas das suas características mecânicas. Visando mitigar este problema, propõe-se o estudo do comportamento deste compósito com resíduos, adicionando fibras. O objetivo desse trabalho foi a análise do comportamento mecânico de concretos produzidos com agregado reciclado e fibras de aço e de vidro do tipo AR. Foram executados dois traços base, o de referência com agregado natural e o traço com 30% de substituição do agregado natural pelo agregado reciclado. A partir destes dois traços base foram produzidos concretos com porcentagens, em volume, de 0,25%, 0,38% e 0,50% de fibras, tanto de aço, como de vidro AR, totalizando 14 traços. Foram determinadas a resistência à compressão axial, resistência à tração, módulo de elasticidade, capacidade de absorção de água e massa específica. Os resultados obtidos foram analisados com auxílio da análise de variância (ANOVA). Foi possível verificar que a resistência à compressão, aos 28 dias, tende a aumentar quanto maior o teor de fibra, principalmente com o uso de agregado reciclado. Quando se aumenta o teor de fibras de aço ocorre aumento no módulo de elasticidade, sendo que esse comportamento não é observado para o concreto com a fibra de vidro AR. Para os ensaios de absorção e massa específica, o tipo de agregado não influencia de maneira significativa no comportamento dos concretos estudados.
A câmara de nuvens como estratégia pedagógica para o ensino de raios cósmicos
Authors: Cabral Raphaella Bahia Soares , Ferreira Giovana Cougo , de Mendonça João Guidugli , de Souza Sarah El Haouche Teixeira
Published: May 2022

Os raios cósmicos são partículas ultrapenetrantes advindas de eventos cósmicos diversos que atravessam a atmosfera e atingem a superfície terrestre. Neste trabalho, pretendemos explicar o que são raios cósmicos, sua detecção e a construção de uma câmara de nuvens. Esperamos, ainda, propor uma metodologia de ensino-aprendizagem dos conhecimentos e saberes pertinentes aos fenômenos físicos envolvendo raios cósmicos por meio da aprendizagem baseada em projetos. Nessa perspectiva, os estudantes desenvolveram um projeto de construção de uma câmara de nuvens e registraram a detecção desses raios na câmara.
Yang-Mills-Shaw e as equações de Maxwell não-Abelianas
Authors: Furtado J. , Helaÿel-Neto J.A.
Published: May 2022

Este artigo tem como objetivo principal apresentar, de maneira sucinta e intuitiva, aspectos fundamentais da construção e do do desenvolvimento da Teoria de Yang-Mills-Shaw. Partindo do paradigma do Eletromagnetismo de Maxwell, construímos, por analogia, a teoria para campos vetoriais não-Abelianos e sua interação com a matéria. Para tal, estendemos o grupo U ( 1 ) do eletromagnetismo para o grupo SU ( N ) e escrevemos as equações tipo-Maxwell para o caso de simetrias não-Abelianas, definindo os campos elétricos e magnéticos associados para a simetria SU ( N ).
DIAGNÓSTICOS DE ENFERMAGEM PARA PESSOAS VIVENDO COM HIV: RELAÇÕES ENTRE TERMINOLOGIAS
Authors: Rocha Cintia Capistrano Teixeira , Lima Dhyanine Morais de , Menezes Harlon França de , Silva Rudval Souza da , Sousa Paulino Artur Ferreira de , Silva Richardson Augusto Rosendo da
Published: May 2022

RESUMO Objetivos: identificar as relações entre os diagnósticos de enfermagem para pessoas vivendo com HIV das terminologias NANDA-Internacional e Classificação Internacional para a Prática de Enfermagem (CIPE®) e validar a equivalência de significados dos diagnósticos entre os sistemas de linguagem. Método: estudo transversal, realizado em um hospital de referência no Nordeste do Brasil, constituído pelas etapas: 1) Identificação dos achados clínicos por meio de entrevista e exame físico com pessoas que viviam com HIV norteada por um roteiro validado; 2) Estruturação dos diagnósticos de enfermagem por meio do julgamento clínico de Risner; 3) Mapeamento cruzado dos enunciados de diagnósticos de enfermagem com os sistemas de classificação da NANDA-I e CIPE®; 4) Validação de conteúdo utilizando a técnica Delphi, em duas rodadas, com enfermeiros especialistas, para os diagnósticos com equivalência de significados entre os sistemas. A coleta de dados ocorreu no período de agosto a novembro de 2018. Resultados: na elaboração e identificação dos diagnósticos obtiveram-se 135 diagnósticos de enfermagem, destes, 62% (n=84) constam da terminologia da CIPE® e 38% (n=51), da NANDA-Internacional. Para 81% (n=68) dos diagnósticos de enfermagem da CIPE® foi identificada a ausência de mapeamento direto na NANDA-Internacional, constando 19% (n=16). O estudo evidenciou que 47 diagnósticos apresentaram equivalência de significados. Conclusão: ambos os sistemas possibilitam a identificação de diagnósticos de enfermagem com acurácia e possuem a capacidade de auxiliar na elaboração de um plano de cuidados individualizado para pessoas vivendo com HIV.
Individual integrity and public morality in scientific publishing
Authors: Della-Sala Sergio
Published: May 2022

ABSTRACT. Science and science reporting are under threat. Knowingly or not, researchers and clinicians are part of this debacle. This is not due so much to the notorious replication crisis, as to our acceptance of lowering common morality for personal gains, including the widespread, deprecable phenomenon of predatory publishing. Rather than fiercefully countering this loathsome practice, academics are accepting, often supporting a masquerade solution: paying several thousand dollars to publish for all their own papers. This new policy will create a disparity across richer and poorer disciplines; will result in concentrating even more in the hands of large, rich, Western institutions, also penalising younger researchers; will kill observational studies and exploratory research; and will make disseminating science depending more on finances than on quality. This article calls for the full awareness of the academic community on the risks of the current situation in scientific publishing.
INTERCROPPING OF EGGPLANT AND TOMATO AS FUNCTION OF TIMES OF TRANSPLANT AND CROPPING SEASON
Authors: CECÍLIO FILHO ARTHUR BERNARDES , ALVES ANARLETE URSULINO , GALATI VANESSA CURY , BEZERRA NETO FRANCISCO , BARBOSA JOSÉ CARLOS , MACHADO BELIZA QUEIROZ VIEIRA
Published: May 2022

ABSTRACT The use of intercropping system allows crops to better utilize inputs supplied and the productive capacity of the area, which can be advantageous to the farmer. Thus, the aim of this study was to evaluate the production performance of eggplant and industrial tomato intercropped as a function of the date of eggplant transplantation compared with tomato transplantation, in two seasons. Ten dates of eggplant transplantation were evaluated (-30, -25, -20, -15, -10, -5, 0, + 5, +10 and +15 days compared with tomato transplantation), with the first season from February to September 2009 and the second from August 2009 to February 2010. The number of commercial fruits per plant, commercial yield per plant and commercial yield of eggplant and tomato were influenced by the date of transplanting of eggplant. Highest eggplant yields were obtained in the second season, due to the more favorable weather conditions for the development of this crop. Late eggplant transplants resulted in yield losses due to tomato interference. For tomatoes, the later the eggplant was transplanted, the higher the yield. Therefore, it is concluded that the species have a high degree of interference with each other and the variation in the time of eggplant transplantation influenced the production characters of both crops. In terms of production, the intercropping of these species may not be economically viable for the farmer due to negative influences on the growth, development and production of these crops.
CAN PUMPKIN BE USED AS A MELLIFEROUS PLANT?
Authors: DA SILVA NATÁLIA CAMPOS , DE QUEIRÓZ MANOEL ABILIO , BARBOSA GRAZIELA DA SILVA , COUTINHO MILENA DOS SANTOS , LIMA NETO IZAIAS DA SILVA
Published: May 2022

ABSTRACT The aim of this paper was to study nectar in male and female flowers of pumpkin (Cucurbita moschata Duch) accessions, aiming at evaluating the species potential as a melliferous plant. Two experiments were conducted in an experimental area of the State University of Bahia, at the Department of Technology and Social Sciences, in Juazeiro-BA, in the period from January to December 2017. Nectar volume, soluble solids, and pH were evaluated in the two floral types using 32 accessions and Tetsukabuto hybrid, which was used as check. Using a sample of accessions, the types of sugar present in the nectar were studied. Male flowers did not have significant differences in nectar traits; however, there was significant variation in female flowers in the first experiment and in both floral types in the second experiment. In male flowers in both experiments, the maximum volume of nectar was 310 μL and in female flowers it was 803 μL. The sugar concentration was around 24 °Brix. Sucrose was similar in both floral types and was higher than glucose and fructose contents, showing mean values of 1,306.13, 357.14 and 351.88 g.mL−1, respectively. Obtaining progeny with contrasting characters in the accessions will be important for species improvement. These results indicate that pumpkin might be considered as a melliferous plant with great potential.
PHYSIOLOGICAL ADJUSTMENTS, YIELD INCREASE AND FIBER QUALITY OF 'BRS RUBI' NATURALLY COLORED COTTON UNDER SILICON DOSES
Authors: FERRAZ RENER LUCIANO DE SOUZA , COSTA PATRÍCIA DA SILVA , MAGALHÃES IVOMBERG DOURADO , VIÉGAS PEDRO ROBERTO ALMEIDA , DANTAS NETO JOSÉ , MELO ALBERTO SOARES DE
Published: May 2022

ABSTRACT Globally, the demand for food and consumer products has accompanied population growth, forcing the agriculture and livestock sector to optimize the production systems. In the specific case of agriculture, using improved edible and energetic plant cultivars associated with abiotic stress-reducing substances is a strategy adopted to solve this problem. This investigation aimed to evaluate whether silicon (Si) promotes physiological adjustments, an increase in production, higher yield, and improved quality of naturally colored cotton fibers. Five doses of silicon (0 (control), 5, 10, 15, and 20 kg ha−1) were tested in a completely randomized design. The variables assessed were physiological adjustments, production, yield and quality of fibers produced by BRS Rubi cultivar. Data were submitted to principal component analysis, multivariate and univariate analyses of variance, and multiple linear regression analysis. Silicon promotes physiological adjustments, enhanced production, yield, and quality of naturally colored cotton fibers of BRS Rubi cultivar grown in the Brazilian semiarid region. Fiber quality in plants that have been treated with Si is within the expected values for this cultivar and by the international standard D-4605 of the American Society for Testing and Materials. 10 kg ha−1 of Si is recommended to increase fiber quality of naturally colored cotton cv. BRS Rubi.
PRODUCTION AND YIELD OF ONION UNDER DIFFERENT WATER AND NUTRITION MANAGEMENTS
Authors: MASSARANDUBA WENDEL DE MELO , GOMES FILHO RAIMUNDO RODRIGUES , BRITO MARCOS ERIC BARBOSA , CARVALHO CLAYTON MOURA DE , ARAÚJO RYCHARDSON ROCHA DE , OLIVEIRA THIAGO HERBERT SANTOS
Published: May 2022

ABSTRACT The objective of this study was to evaluate the effect of different irrigation depths applied by drip system and nitrogen fertilization levels that promote higher yield and water use efficiency in onion (Allium cepa L.). The treatments consisted of five irrigation depths (50; 75; 100; 125; 150% of crop evapotranspiration), applied by drip system, combined with five nitrogen fertilization rates (0, 40, 80, 120 and 160 kg ha−1), in a 5 x 5 factorial scheme, in a randomized block experimental design, with four replicates. Irrigation depths estimated at 120.2% and 77.81% of crop evapotranspiration promoted higher yield and water use efficiency for total yield of onion bulbs, respectively. Nitrogen dose of 160 kg ha−1 promoted maximum total yield and water use efficiency.
ROOT DISTRIBUTION, NUTRIENT CONCENTRATION AND ACCUMULATION IN ‘GIGANTE’ CACTUS PEAR IRRIGATED WITH SALINE WATER
Authors: FONSECA VARLEY ANDRADE , DOS SANTOS MARCELO ROCHA , DONATO SÉRGIO LUIZ RODRIGUES , DA SILVA JOÃO ABEL , BRITO CLEITON FERNANDO BARBOSA
Published: May 2022

ABSTRACT In semiarid regions with greater climatic variability, including prolonged droughts and delayed rainy seasons, supplemental irrigation is critical to ensuring yields of forage cactus pear. The objective was to evaluate root distribution and nutrient concentration and accumulation in ‘Gigante’ forage cactus pear subjected to different irrigation regimes. Seven irrigation regimes were tested: no irrigation (rainfed); five liters of medium-salinity water, with an electrical conductivity (EC) of 0.75 dS m−1, applied per linear meter every 15 days; 7% reference evapotranspiration (ETo) with a 15-d irrigation interval (II); 15% ETo with a 7-d II; 33% ETo with a 3-d II; 50% ETo with a 2-d II; and 100% ETo, irrigated daily - high-salinity water, EC of 3.6 dS m−1, was used in the last five treatments. The treatments were laid out in a randomized block design with four replicates. Roots developed best in plants irrigated at 50% ETo with a 7-d II. Applying high-salinity water at 15% ETo with a 7-d irrigation interval promotes higher concentrations of P, Ca, Mg and S in cladodes of cactus pear. Applying high-salinity water at 33% ETo with a 3-d II promotes higher uptake/accumulation of P, Ca, Mg, S and Zn in cladodes of ‘Gigante’ forage cactus pear.
Physiological and molecular changes in seeds of Hancornia speciosa Gomes stored in conservative solutions
Authors: Nunes Valdinete Vieira , Silva-Mann Renata , Souza Juliana Lopes , Lima Laura Catharine Dória Prata , Torres Maria Fernanda Oliveira , Álvares-Carvalho Sheila Valéria
Published: May 2022

Abstract: For native species in Brazil, there is a great need for scientific information that allows efficient production and storage of seeds. The present work evaluated the physiological and molecular changes in Hancornia speciosa seeds stored in conservative solutions. The experiment was carried out in a completely randomized design, in a split-plot scheme, with eight replications. In the plots, the conservative solutions (A, B, C, and D) were allocated, and the subplots the storage periods (50, 100, 150, and 200 days). The following variables were analyzed: water content, X-ray, germination, shoot length, root, dry mass of seedlings, electrical conductivity, concentration and quality of ribonucleic acid, the concentration of peroxidase, and heat-resistant proteins. The water content remained above 50%, and 88% of the seeds are full and well-formed. There is a reduction in the germination, shoot length, root, and dry mass of seedlings; and an increase of electrical conductivity with the increase of the storage time. Heat-resistant proteins were not sufficient to protect seeds against macromolecular damage, and RNA and peroxidase concentrations decreased with the increase of the storage time. The seeds stored in solutions B and C are more vigorous, being such solutions indicated for the conservation of H. speciosa.
Protein profile in arabica coffee seeds in electrophoresis gel: importance of freeze-drying
Authors: Fávaris Nathália Aparecida Bragança , Rosa Sttela Dellyzete Veiga Franco da , Figueiredo Madeleine Alves de , Coelho Stefânia Vilas Boas , Vilela Ana Luiza de Oliveira , Padilha Lilian
Published: May 2022

Abstract: Coffee seeds are sensitive to desiccation and are used or stored with different moisture content values, which may affect the results of quality assessment. The aim of this study was to evaluate the changes in protein profile in electrophoresis gel in coffee seeds with different moisture content values under freeze-drying and without freeze-drying. Two lots of arabica coffee seeds were used, one of newly-harvested seeds and another of stored seeds. The seeds were dried to the moisture content values of 12, 15, 20, 25, 30, 35, and 40%. The physiological quality of the seeds was assessed through the germination test, electrical conductivity, and the profiles of the enzymes SOD, CAT, PO, GOT, MDH, and EST and of heat-resistant proteins. In general, there is an effect on expression of these enzymes in accordance with the presence of free water in the seeds. Moist seeds have little to no enzyme expression. The freeze-drying process allows preservation of coffee seed quality and does not change the functionality of the enzymes studied. The isoenzyme profiles of the antioxidant process in arabica coffee seeds are affected by the initial moisture content of the seeds. The freeze-drying process of the seeds ensures greater sensitivity in detection of the expression of these isoenzymes.
The hydrolysis dynamic of storage reserves in maize seed germination helps to explain differences in inbred lines and hybrid seed vigor
Authors: Nerling Daniele , Coelho Cileide Maria Medeiros , Brümmer Adriele
Published: May 2022

Abstract: Storage reserves composition is directly related to the manifestation of seed vigor. However, the physiological potential expression in inbred lines, as well as hybrids from the storage reserves hydrolysis, is not clear. Thus, the aim of this study was focused on verifying if there are differences in the hydrolysis of seed storage reserve of maize inbred lines or hybrids during germination, and also checking if the changes in hydrolysis are associated with seed vigor. The seeds of inbred lines and hybrids were submitted to germination test, vigor by accelerated aging and cold tolerance. Biochemical profiling (total protein content, soluble proteins, phytate, inorganic phosphorus, starch, and soluble sugars), was temporally determined at 0 h (quiescent seeds), 12 h, 24 h, 30 h, and 48 h after imbibition. The seeds of inbred lines showed a longer time for root protrusion and less vigor when compared to hybrids. The highest hydrolysis rates in inbred lines were observed in phase I and at the end of phase II of germination. In hybrids, the rates remained, on average, constant throughout germination. The greatest differences in the hydrolysis of reserve compounds occur in phase II of germination and differentiate the germination metabolism of hybrids and inbred lines.
Nurses’ perception regarding their health and working conditions during the COVID-19 pandemic
Authors: Galon Tanyse , Navarro Vera Lucia , Gonçalves Angélica Martins de Souza
Published: May 2022

Abstract Objective: to identify working conditions and their effects on nursing professionals’ health during the COVID-19 pandemic, based on the workers’ own perceptions. Methods: qualitative research carried out with 15 nursing professionals interviewed through online focus group. We analyzed the interviews content based on hermeneutics-dialectics. Results: nurses reported that the pandemic worsened their historic, chronic, and precarious working and health conditions, marked by increased workload, lack of personal protection equipment and material resources, shortage of professionals and devaluation of their jobs, generating a perceived dehumanization at work, with nurses feeling as “machines” and “numbers”. Mental suffering due to the risk of contamination, the frequent death of co-workers, patients, and family members, lack of societal support concerning protective measures, and the increasing demands for performance and productivity generates anxiety, depression, and stress. Conclusion: the COVID-19 pandemic enhanced nurses’ mental suffering and the precariousness of their work, urging the improvement of their working conditions and health promotion, essential for workers’ protection and dignity.
Brasil, 200 anos de devastação O que restará do país após 2022?
Authors: Marques Luiz
Published: May 2022

RESUMO Duas constantes atravessam nossa história nos dois últimos séculos: a escravidão e seu legado nas relações entre os humanos, e a destruição nas relações dos humanos com a paisagem natural e com as outras espécies. O presente artigo atém-se a uma breve análise desse segundo traço estruturante da sociedade brasileira. O discurso proferido em 1823 por José Bonifácio de Andrada e Silva assinala o ponto de partida de um processo que só viria desde então a se agravar. Após 200 anos de destruição, três evidências se acumulam: 1- após 50 anos (1970-2020) de destruição e degradação de mais de 2 milhões de km2 dos biomas nacionais, a sociedade brasileira avança na direção de uma catástrofe ambiental sem precedentes em nossa história; 2- esse avanço se acelerou no último decênio; e 3- múltiplos indicadores permitem afirmar que já estamos nos estágios iniciais desse colapso.
Educação, sociedade e democracia: o legado de John Goodlad
Authors: Fernandes Domingos
Published: May 2022

RESUMO O principal propósito deste artigo é apresentar e discutir algumas das ideias mais relevantes da extensa e intensa obra de John Goodlad (1920-2014) no que se refere a questões relacionadas com a renovação e a melhoria da educação, das escolas e da sociedade democrática e social. Por meio da leitura e da consulta de alguns dos seus textos reconhecidamente mais influentes, foi possível, por um lado, produzir uma breve síntese biográfica do autor e, por outro, identificar algumas das linhas mestras que orientaram o seu pensamento e a sua ação cívica. As suas pesquisas e a sua incansável luta para melhorar a educação e a democracia, que perspetivava numa relação simbiótica, foram sempre orientadas pela ideia de que o conhecimento sociológico crítico e profundo das escolas é uma condição indispensável para a sua renovação e melhoria. E esse é, muito provavelmente, o seu mais fundamental legado.
Ensinar longe da escola: ensaio sobre as representações em E. Durkheim e R. Chartier
Authors: Menezes Roni Cleber Dias de , Silva Vivian Batista da
Published: May 2022

RESUMO Após meses com as salas de aula fechadas, professores e alunos ainda não vislumbram quando se poderá voltar às escolas. Roger Chartier, no artigo “Mundo pós-pandemia”, publicado em 1º de junho na página virtual do Sesc-SP, destaca a “infinita tristeza do ensino” no isolamento. Na esteira dessa percepção, vimos desde a interrupção das aulas avaliações as mais diversas sobre o papel da instituição escolar e da socialização que ela realiza para a formação educacional da infância e juventude. Interessados em alargar a visão sobre o tema, propomos historicizar o que chamamos aqui de “imagem da sala de aula”. Para concretizar nosso propósito, escolhemos para análise as imagens presentes nas famosas histórias em quadrinhos francesas do Petit Nicholas, assinadas por René Goscinny e ilustradas por Jean-Jacques Sempé entre 1956 e 1964. Tais imagens serão interpeladas com o auxílio da noção de representação, na voz de autores há muito tempo lidos e relidos entre os educadores: Émile Durkheim e Roger Chartier. O uso do conceito de representação nos será útil para explorar as múltiplas respostas dos autores de seus respectivos tempos históricos sobre os problemas e as potências da escola. Lembrando as palavras de Ítalo Calvino (1993), convém dedicarmos um tempo para revisitar leituras importantes de nossa formação. As referências permanecem as mesmas, mas nossas trajetórias e desafios mudam. A atual situação é um convite à releitura dessas obras “clássicas” que, pela sua fecundidade, sobretudo quando explicam a força da representação, permitem refletir sobre a construção do desejável em educação hoje.
Avaliação da funcionalização da superfície de microfibras de aço com Tetraeoxissilano (TEOS) e Glixidoxipropriltrimetoxissilano (GPTMS)
Authors: Casagrande Cézar Augusto , Jochem Lidiane Fernanda , Repette Wellington Longuini
Published: May 2022

RESUMO Fibras de aço são largamente utilizadas para os mais diversos fins na construção civil. A principal utilização é para reforço estrutural. Nessa aplicação as fibras atuam como ponte de transferência de tensão no compósito por meio do atrito entre a fibra e a matriz. Um meio para potencializar a aplicação de fibras em compósitos cimentícios é a alteração da superfície das fibras por meios físico químicos de modo proporcionar maior interação entre a fibra e a matriz. Neste trabalho é proposto um tratamento químico com dois tipos de silano, o Tetraetoxissilano (TEOS) e o Glicidoxipropiltrimetoxissilano (GPTMS). Foram realizados tratamentos de funcionalização por processo úmido e rota ácida com banhos sequenciais e cura após tratamento com silanos em porções de 1 e 10% em volume na solução e posteriormente analisados por MEV/EDS e método gravimétrico. Foram obtidas fibras de aço com silanos depositados em sua superfície. Foi verificado que quanto maior a concentração do banho de silano, maior é a deposição de silano na superfície das fibras. Em paralelo, verificou-se o aumento expressivo da concentração de silício em função do teor de silano nos banhos de funcionalização. Também se verificou que os filmes de silano quando espessos apresentam fragilidade à abrasão, sendo possível remover parte do filme por meio do atrito entre as fibras.
Dopamine Receptors in Breast Cancer: Prevalence, Signaling, and Therapeutic Applications
Authors: Ben-Jonathan Nira , Borcherding Dana C. , Hugo Eric R.
Published: May 2022

Breast cancer (BC) is the most common malignancy among women, with over one million cases occurring annually worldwide. Although therapies against estrogen receptors and HER2 have improved response rate and survival, patients with advanced disease, who are resistant to anti-hormonal therapy and/or to chemotherapy, have limited treatment options for reducing morbidity and mortality. These limitations provide major incentives for developing new, effective, and personalized therapeutic interventions. This review presents evidence on the involvement of dopamine (DA) and its type 1 receptors (D1R) in BC. DA is produced in multiple peripheral organs and is present in the systemic circulation in significant amounts. D1R is overexpressed in ~ 30% of BC cases and is associated with advanced disease and shortened patient survival. Activation of D1R, which signals via the cGMP/PKG pathway, results in apoptosis, inhibition of cell invasion, and increased chemosensitivity in multiple BC cell lines. Fenoldopam, a peripheral D1R agonist that does not penetrate the brain, dramatically suppressed tumor growth in mouse models with D1R-expressing BC xenografts. It is proposed that D1R should serve as a novel diagnostic/prognostic factor through the use of currently available D1R detection methods. Fenoldopam, which is FDA-approved to treat renal hypertension, could be repurposed as an effective therapeutic agent for patients with D1R-expressing tumors. Several drugs that interfere with the cGMP/PKG pathway and are approved for treating other diseases should also be considered as potential treatments for BC.