bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparative Legal History: uma combinação produtiva?
Authors: Sordi Bernardo
Published: September 2022

The text intends to discuss the limits and possibilities of Comparative legal history. Although it played an important informative role, the descriptive and na-tionalist legal comparison of the last century finds its limits today. The current Comparative legal history project takes on the new problems of spatial mapping of legal history beyond national histories. The new historical-comparative perspective must, therefore, attenuate the centralist perspective, which dimin-ishes the role of the peripheries and understands their history in terms of the center. Within the frame-work of a European history of public law, the methods are still being refined; cross-reads, improved and syn-chronized. The difficulties of this research project are many, imposed by chronologies, the different weights of political fractures, the question of borders and the difficult legacy of colonialism.Keywords:Comparative legal history; Research methodology in legal history; History of public law; Transnational aspects; European legal experience.*Professor Doutor Catedrático da Università degli Studi di Firenzi, Itália.bernardo.sordi@unifi.it**Doutor em Direito pela Universidade de Brasília. Professor do Programa de Pós-Graduação em Direito da UFERSA.Professor do IDP, Brasília.raphapeixoto@gmail.comRecebido em 14-7-2022|Aprovado em 14-7-202211Artigo convidado. Nota do tradutor:tradução autorizada pelo autor.Resumo e palavras-chaves elaboradaspelo tradutor.A versão original em italiano foi apresentada no Seminário Diritto: storia e comparazione,realizado
A locomotiva do tempo da história: o rádio durante o primeiro governo de Getúlio Vargas – 1930 a 1945
Authors: Fernando Rigo Joanir
Published: September 2022

The radio has played a significant role during GetúlioVargas’ first government in Brazil –1930-1945. In ad-dition to being used as a political tool, the radio may have contributed to the perception that the time of events was shortened. This paper aims to analyse whether Reinhart Koselleck’s concept of time acceler-ation in history could be applied to the use of Radio during that period. By the end of this study, it was found that not only the speed of communications changed due to the new technology, but also its use may have contributed to the rapid social changes that took place. The radio was, in that context, the “loco-motive” of time acceleration experience.
Teoria da argumentação jurídica: análise da tópica de Viehweg
Authors: Arruda Lorena , Sousa Renan
Published: September 2022

This article aims to study the link between topical and legal arguments, initially proposed by Theodor Viehweg and the member of the member of the Mainz School and the dynamic system. Through the study of rhetoric, which addresses the ways in which a speech persuades an audience on a certain topic and the juridic topic, which aims to solve basics issues with the help of arguments supported by common sense or the opinion of the authorities. A thought that isbases on rhetoric and topic helps to understand the production of legal decisions in Brazilian state agen-cies. This article is divided into three parts. The first analyzes the relationship between topic and law. In the second part, the legal argument is analyzed by the study of Theodor Viehweg ́s proposal. In the third part, the importance of the topic as a technique for rationalizing interpretations in Law will be analyzed.
Netnografia em Administração: Uma Bibliometria em Publicações Brasileiras
Authors: Medeiros Henriques Flávio , Cruz Mendes Renato
Published: September 2022

A netnografia é um método de pesquisa desenvolvido em 1998 por Robert. V. Kozinets e pode ser descrita como um método qualitativo interpretativo que adapta as tradicionais técnicas antropológicas da pesquisa etnográfica ao estudo de culturas online e comunidades virtuais. Desenvolvida no campo dos estudos de cultura e consumo, a netnografia representa um esforço de criar uma alternativa metodológica que viabiliza o estudo das culturas e comunidades de consumo construídas por consumidores através da internet. O objetivo deste trabalho é investigar a trajetória da netnografia nas publicações brasileiras. Para isso, foi realizado um estudo bibliométrico levando-se em conta artigos publicados em periódicos brasileiros indexados pela CAPES na área de avaliação “Administração Pública e de Empresas, Ciências Contábeis e Turismo”. Os principais resultados confirmam a predominância de estudos netnográficos no âmbito do marketing, especialmente no campo do comportamento do consumidor. Contudo, existem evidências de que outras áreas de conhecimentos, como a educação e saúde, estejam utilizando a netnografia para estudar outras temáticas que podem ser exploradas no âmbito das comunidades virtuais online.
Conscientização do homem acerca de sua responsabilidade de escolha a partir do conceito de Liberdade em Jean Paul Sartre
Authors: De Avila Ramos Paula , Leite Reis Thaís
Published: September 2022

Este trabalho enfoca a temática da liberdade na perspectiva fenomenológico-existencial, com vistas a uma reflexão, de forma atuante, abstendo-se do conceito de libertinagem e buscando compreender o homem como responsável por suas escolhas, que tangem de igual modo o individual e o coletivo, já que age livremente dentro do que considera possível não somente para si, mas também para todo o social ao seu redor. A concepção de liberdade, considerada neste artigo, se apresenta como a única condenação presente na existência do homem, de modo a movimentar sua trajetória entre escolhas, atos, consequências e angústias, além de revelar a possibilidade de se assumir autêntico no que elege frente às intempéries que a realidade pode apresentar. O objetivo deste trabalho é trazer à luz a conscientização do homem enquanto um ser relacional, onde, ao mesmo tempo em que afeta o mundo, é também afetado por ele, o que revela a responsabilidade de suas ações e seu papel transformador na sociedade. Para discorrer sobre tal tema e seus desdobramentos lançamos mão do autor, filósofo francês e escritor: Jean Paul Sartre.
Ética e Presença: efeitos da pandemia do COVID-19 nas práticas dos profissionais da Psicologia no Brasil
Authors: Braga Nogueira Cleto Letícia , Rodrigues de Oliveira Geovana
Published: September 2022

O advento da pandemia do novo coronavírus provocou mudanças repentinas que atingiram os mais diversos aspectos da vida humana. Diante disso, alguns processos esperados para o futuro foram acelerados e colocados à prática, como a utilização da tecnologia para mais atividades do cotidiano e o uso de também dela para serviços de saúde. Estudos da FioCruz (2020), apontaram que uma população exposta a uma pandemia pode sofrer manifestações psicopatológicas, caso não seja feito um trabalho voltado à saúde mental. Em tais condições, os impactos são psicossociais e de acordo com o tamanho da pandemia e o grau de vulnerabilidade de cada pessoa. Desta forma, o presente trabalho tem como objetivo discutir como a pandemia do COVID-19 influenciou na atuação do psicólogo e como a ciência psicológica se estruturou em sua ética e práxis para promover saúde mental nesse contexto. Propõe também, uma reflexão acerca das possíveis contribuições da mesma para a diminuição das desigualdades sociais que ficaram mais atenuadas nesse momento. Conclui-se que durante a pandemia, o psicólogo ficou limitado em certas situações, se adaptou e repensou alguns posicionamentos. Iniciativas de projetos sociais que atendam a população mais vulnerável foram presentes e de extrema necessidade para contribuir com ações que buscaram amenizar as consequências de tal contexto, principalmente para grupos minoritários que foram atingidos de forma expressiva.
Epidemiologia do câncer de próstata no Brasil nos últimos 10 anos
Authors: Gomes do Nascimento Eduarda , Filgueiras de Carvalho Gabriel Augusto , Paiva da Costa Jardim Gabriela , Lopes Dias Juliana , Serpa de Figueiredo Junior Hélcio
Published: September 2022

O câncer de próstata é o que mais acomete homens no país, principalmente idosos com mais de 65 anos. Sendo assim, o objetivo foi avaliar a perspectiva do câncer de próstata no Brasil nos últimos 10 anos, tendo como foco relacionar dados relevantes como número de internações, faixa etária e taxa de mortalidade com a bibliografia coletada. Para isso, foi realizada uma coleta observacional, descritiva e transversal de dados do DATASUS - Sistema de Informações Hospitalares do Sistema Único de Saúde (SIH/SUS) do Ministério da Saúde. Como resultado, o número de internações foi de 282.736, com taxa de mortalidade de 9,15 e maior acometimento a partir dos 50 anos e na etnia branca. A partir disso, foi constatado que os números da doença estão aumentando a cada ano, associado a alta taxa de mortalidade. Por esse motivo, é necessário realizar estudos epidemiológicos aprofundados e conscientizar a população a respeito da doença, a fim de possibilitar um melhor controle dela no Brasil.

Palavras-chave: Câncer de Próstata; Neoplasia Maligna da Próstata; Epidemiologia.
Tratamento não farmacológico na síndrome de abstinência alcoólica: Revisão de literatura
Authors: Moras Vicentino Vitória Maria , Barroso Werneck Márcia
Published: September 2022

A síndrome de abstinência alcoólica é caracterizada por sinais e sintomas  após abstinência ou diminuição do consumo crônico do álcool. O objetivo desse trabalho foi comparar fatores que podem interferir antes, durante e após , na eficácia do tratamento não farmacológico da abstinência alcoólica. Trata-se de uma revisão integrativa de literatura que utilizou os seguintes descritores: treatment, alcoholic abstinence e symptoms. Foram selecionados, após critérios de inclusão e exclusão nos últimos 5 anos (2016 a 2021), 26 artigos das bases de dados PubMed e BVS. Os fatores que influenciaram antes no tratamento da abstinência alcoólica foram o paciente possuir uma personalidade dotada de autocontrole, rastreamento sobre o abuso de álcool e explorar a trajetória anterior ao tratamento. Entre os fatores que influenciam durante e após o início da abstinência alcoólica estão a inclusão de novas tecnologias, utilização de terapia psicológica e comportamental, além da individualização das metas de consumo. O rastreamento para uso abusivo de álcool deve ser realizado na atenção primária para encontrar casos de alcoolismo iniciais. A instituição de alvos individualizados de consumo diminui as recidivas. A utilização de terapias aumenta o autocontrole e as expectativas do paciente. Por fim, a utilização de internet aproxima o dependente da equipe de saúde e facilita o acompanhamento. Logo, para abordagem efetiva da abstinência alcoólica, o sistema de saúde deve possuir sistema de rastreamento para o consumo abusivo do álcool, inserir terapia psicológica e comportamental no tratamento, calcular meta de consumo personalizada e possuir abordagem que utilize novas tecnologias envolvendo a internet.
Paciente oncológica com obstrução do trato gastrointestinal: um relato de caso entre as clínicas médica e cirúrgica
Authors: Côrtes Vieira João Antonio , Chiapini Ornellas Rhafaela , Vidal Teixeira Carlos Roberto , Trovão Queiroz Aline
Published: September 2022

Dentre todos os cânceres, o carcinoma colorretal é o terceiro tipo mais prevalente e segundo em maior mortalidade, tanto no Brasil quanto no mundo. Sua etiologia está relacionada a diversos fatores genéticos e ambientais ainda não tão bem compreendidos. Este relato discorre sobre uma paciente sem histórico familiar ou fatores de risco para câncer de cólo a exceção da raça, que foi diagnosticada com uma doença em estágio IV aos 49 anos, após evoluir com um quadro de sub-oclusão intestinal. Apesar do prognóstico reservado, acabou apresentando uma resposta satisfatória e duradoura ao tratamento quimioterápico. Além disso, mesmo necessitando ser submetida a uma jejunostomia descompressiva a apenas 1,5 metros do ângulo Treiz, a paciente também se adaptou bem a nova condição pós-cirúrgica, não evoluindo para um quadro de síndrome do intestino curto. Este trabalho demonstra a importância de mais estudos acerca dos diferentes fatores acerca desta patologia tão prevalente, bem como a importância de se investir no tratamento mesmo de casos mais avançados da doença, desde que não ultrapasse os limites da distanásia.
Barreiras ao Acesso do Rastreamento e Detecção Precoce da Neoplasia de Colo de Útero
Authors: Alves Leite da Luz Oliveira Gabriela , Moreira Penedo Mariana , Hybner Gonçalves Matheus , Anderi Stephanie , Aparecido Caetano Oswaldo
Published: September 2022

Resumo

O câncer de colo de útero (CCU) tem evolução lenta, com alta taxa de letalidade, porém tem alto potencial de prevenção e cura. O exame utilizado em seu rastreamento é o Papanicolau. Junto à infecção ao Papiloma Vírus Humano (HPV), existem fatores de risco que aumentam a possibilidade do CCU. Desse modo, programas que incentivem o rastreamento podem diminuir a incidência e mortalidade desta neoplasia. O objetivo do estudo foi analisar as barreiras para o acesso ao rastreamento e diagnostico precoce do câncer de colo de útero. Foi realizada uma revisão integrativa de literatura, com levantamento bibiográfico nos bancos de dados PubMed e Biblioteca Virtual em Saúde, com a utilização  dos critérios de inclusão e exclusão, além dos filtros, em que ao final da pesquisa foram encontrados 20 artigos. Após a análise dos artigos foi observado que as principais barreiras para o rastreamento e detecção precoce foram a falta de informação e conhecimento, medo de realizar o exame e e encontrar um resultado positivo, falta de acesso, sendo este de transporte ou localização e financeiro. Desse modo, pode-se observar que grande parte das mulheres não fazem o rastreamento, comprovando que as barreiras analisadas impedem que haja uma detecção precoce do CCU, precisando que haja um bom atendimento humanizado, com privacidade, horários acessiveis e informações corretas. Portanto, com as barreiras identificadas é possivel colocar em práticas medidas que diminuem elas e possam elevar a cobertura de rastreamento, sendo possível assim aumentar a sobrevida das pacientes.
Immunometabolism Dysfunction in the Pathophysiology and Treatment of Rheumatoid Arthritis
Authors: Masoumi Maryam , Hashemi Nader , Moadab Fatemeh , Didehdar Mojtaba , Farahani Rahim , Khorramdelazad Hossein , Sahebkar Amirhossein , Johnston Thomas P. , Karami Jafar
Published: September 2022

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial hyperplasia and joint damage. Systemic complications and progressive disability are burdens that lead to a significant socio-economic costs in patients with RA. Current RA biomarkers used in predicting, diagnosing, and monitoring the treatment of the disease have not been very successful. Moreover, only 60% of patients show a satisfactory response to current biological and conventional therapies. Studies on immunometabolism have suggested that dysregulated enzymes, transcription factors, metabolites, and metabolic pathways could be considered potential therapeutic targets for the treatment of RA. Factors such as the high concentration of various intermediate molecules arising from metabolism, hypoxia, lack of nutrients, and other metabolic alterations affect local immune responses and preserve a state of chronic inflammation in synovial tissues. Fortunately, in vitro and in vivo studies have shown that targeting specific metabolic pathways is associated with a decreased level of inflammation. Specifically, targeting metabolic intermediates, such as succinate or lactate, has shown promising clinical outcomes in RA treatment. These findings open an avenue for the identification of novel biomarkers for diagnosis, prognosis, and determining the success of various treatments in RA patients, as well as the discovery of new therapeutic targets.
Implications of CRISPR-Cas9 in Developing Next Generation Biofuel: A Mini-review
Authors: Sharma Pushpender Kumar , Lakhawat Sudarshan Singh , Malik Naveen , Kumar Vikram , Kumar Sunil
Published: September 2022

The major drawbacks of biofuel production at the commercial level are its low yield, nonavailability
of feedstock, feedback inhibition, presence of inhibitory pathways in various organisms,
and biofuel intolerance of organisms. The present review focuses on the implications of the CRISPRCas9
mediated gene editing tool to alter the genome of bacteria, algae, fungi, and higher plants for efficient
biofuel production. Gene knockout and gene cassette insertions employing CRISPR-Cas9 in
Saccharomyces cerevisiae and Kluyveromyces marxianus have resulted in enhanced production of bioethanol
and 2-Phenyl ethanol in these organisms, respectively. Genomes of several bacterial strains
were also modified to enhance ethanol and butanol production in them. CRISPR-Cas9 modification of
microalgae has demonstrated improved total lipid content, a prerequisite for biofuel production. All
over, CRISPR-Cas9 has emerged as a tool of choice for engineering the genome and metabolic pathways
of organisms for producing industrial biofuel. In plant-based biofuel production, the biosynthetic
pathways of lignin interfere with the satisfactory release of fermentable sugars thus hampering efficient
biofuel production. CRISPR-Cas9 has shown a promising role in reducing lignin content in various
plants including barley, switchgrass, and rice straw.
Polymer based Gels: Recent and Future Applications in Drug Delivery
Field
Authors: Siafaka Panoraia I. , Gündoğdu Evren Atlıhan , Cağlar Emre Sefik , Özgenç Emre , Gonzalez-Alvarez Marta , Gonzalez-Alvarez Isabel , Okur Neslihan Üstündağ
Published: September 2022

Background:

Currently, there is ongoing research in the pharmaceutical technology field to
develop innovative drug delivery systems with improved therapeutic efficacy.

Objectives:

Although there is a high need for new drug molecules, most scientists focus on the advancement
of novel pharmaceutical formulations since the present excipients lack important properties
such as low release rate leading to repeated dosing. Aside from this, pharmaceutical technologists aim
to develop drug formulations that can target specific organs and tissues, lowering the possibility of
adverse effects.

Methods:

This review aims to cover the different polymer-based gel types, the development and characterization
methods, as well as applications thereof. Finally, the recent advancements and future perspectives
focusing on radiolabeled gels will be addressed.

Results:

In the last decades, polymer based pharmaceutical gels have shown attractive properties and
therefore have raised the attention of pharmaceutical scientists. Gels are either chemically or physically
cross-linked networks that can absorb fluids such as water(hydrogels), oil (organogels) and even
air(aerogels). A variety of polymers, either synthetic or natural, have been employed as components for
the gels. Stimuli-responsive gels based on stimuli-sensitive polymers are among the most studied gel
class of last years.

Conclusion:

The use of polymer-based gels as drug delivery systems would be beneficial for targeting
numerous diseases.
Association between Maternal Hemoglobin, other Maternal Attributes and
Neonatal Birth Weight: A Case-control Study
Authors: Ranjbaran Mehdi , Javadi Maryam , Zarei Shabnam , Shiri-Shahsavar Mohammad Reza , Jafarimanesh Hadi , Tola Habteyes Hailu
Published: September 2022

Background:

Although the burden of anemia in pregnant women and its consequences on the pregnancy outcome are well documented, there is limited evidence on the association be-tween maternal hemoglobin concentration and low birth weight (LBW) in the study area.

Objectives:

This study aimed to determine the association between maternal hemoglobin concentra-tion and neonatal birth weight (BW) in Qazvin, Iran, 2018-2019.

Materials and Methods:

A case-control study was conducted among 450 neonates with BW < 2500 gm (LBW) and 451 neonates with BW > 2500 gm. In this study, neonates with BW less than 2500 gm were cases, while those who were greater than 2500 gm were considered as control. Multiple logistic regression model was used to calculate OR with 95% Confidence Interval (95 % CI) to determine the association between maternal anemia and other maternal attributes and neonate BW.

Results:

Maternal hemoglobin (g/dl) was not significantly associated with neonate BW (OR: 1.03 (95 % CI: 0.58 - 1.81), p = 0.93). However, maternal initial weight (Kg) (OR: 0.96 (95 % CI: 0.94 - .098), p < 0.001), mother's age in year (OR: 1.04 (95 % CI: 1.00 - 1.09), p = 0.038), gestational age (OR: 0.49 (95 % CI: 0.43 - 0.57), p < 0.001) were significantly associated with neonatal BW.

Conclusion:

Maternal hemoglobin concentration was not significantly associated with LBW. How-ever, other maternal attributes such as low initial maternal weight, low gestational age, low educa-tion status and old age were significantly associated with LBW. Intervention that targeted mothers with low initial weight, low educational status and older age is required to minimize LBW among neonates in the study area.
A New Current Limiting Strategy Based on Id − ω and Iq − V Droop Characteristics for Grid-Connected Distributed Generations
Authors: Saleh Abdolhossein
Published: September 2022

Background:

Increase in the output current of inverter-based Distributed Generations (DGs), which are connected to Upstream Grid (UG) and equipped with droop controller, due to UG frequency and/or voltage magnitude drop is a conventional event. The first solution to limit the output currents is using current limiter circuits at the output side of the grid-connected droop-controlled DG. Suppose the increasing output currents of this DG in continuous UG frequency drop exceeds their maximum. In that case, the current limiter circuits limit them to their maximum values. This limitation is based on the P-ω droop characteristic due to instability because the DG frequency will be greater than the UG frequency. This difference leads to sending and receiving power between DG and UG. To overcome this problem, different methods have been presented in the literature.

Methods:

This paper proposes a method based on a floating droop controller. In this method in order to limit output currents strictly, I_od-ω and I_oq-v droop characteristics are used instead of P-ω and Q-v characteristics, respectively. In the proposed method, instead of increasing the droop coefficients to limit currents, the droop curves are moved downward. Also, two transient supplementary signals are proposed to ensure that instantaneous currents do not have overshoot in the transient state.

Results:

Small-signal stability analysis shows that the system remains stable under the proposed controller. Moreover, the proposed strategy performance is indicated by time-domain simulation results using MATLAB/Simulink software under different case studies.

Conclusion:

The proposed new method limits the output currents of grid-connected droop-controlled DG without using current limiter circuits and performs a stable operation under the abnormal conditions of the grid.
Marine Algal Bioactive Metabolites and their Pharmacological Applications
Authors: Kachhwaha Neetu , Kumar Sharma Mukesh , Khandelwal Renu , Kaushik Pallavi
Published: September 2022

Thousands of bioactive components are derived from various marine macro
and microalgae. Such beneficial algae are considered as a renewable and sustainable
resource of bioactives with potential use as dietary food supplement, anti-viral,
antiinflammatory, anti-cancerous, anti-oxidant, anti-diabetic, anti-bacterial agents
which can provide nutritive and health care benefits. The biochemical infrastructure of
algae comprises proteins, lipids, polysaccharides, minerals, vitamins etc. which can be
used as nutritional and dietary sources along with use in therapeutics and cosmetics.
The therapeutic and industrial applications of the algal derivatives are primarily due to
the secondary metabolites such as astaxanthin, aquamin, alginates, fucoidan, omega-3-
fatty acids, polyphenols, fucoxanthin, etc. This chapter focuses on various algae
derived bioactives and their wide range of applications.
Nutritive Importance and Medicinal Properties of Foeniculum vulgare Mill. (Fennel) and Trachyspermum ammi L. (Ajwain)
Authors: Goswami Nandini , Jain Shalini , Chatterjee Sreemoyee
Published: September 2022

In tropical and sub-tropical countries, spices have a long history in
traditional food preparations. Several spices are described to have medicinal effects.
Among them are Foeniculum vulgare Mill. and Trachyspermum ammi L. belonging to
the Apiaceae family are the most common spices known for their highly aromatic
nature and flavor with culinary and traditional uses. F. vulgare seeds increase urine
flow, improve the digestive system, promote menstruation and improve milk flow.
Various pharmacological activities of F. vulgare such as antioxidant, hepatoprotective,
antimicrobial, estrogenic, acaricidal, antihirutism, antidiabetic, anti-inflammatory, and
antithrombotic, have been reported in the literature. T. ammi seeds are used for
relieving flatulence, dyspepsia, spasmodic disorders, common cold, acute pharyngitis,
sore and congested throat, dipsomania, and hysteria. T. ammi seeds are reported to
possess antimicrobial, antioxidant, hepatoprotective, nematicidal, antihelmintic, and
gastroprotective activities. The review presents an overview of the traditional uses,
phytochemical constituents, and pharmacological properties of F. vulgare and T. ammi
seeds.
Bioactive Constituents and Anti-diabetic Activity of the Indian Medicinal Plant Hemidesmus indicus R. Br.: An Overview
Authors: Kumar Dixit Amit , Banerji Avijit , Banerji Julie , Dixit Deepti , G. Nair Parvathy , Gupta Damodar
Published: September 2022

Hemidesmus indicus R. Br. is a laticiferous, slender, and twining shrub,
which is found over almost every part of India. Its roots (Anantmul - Sanskrit meaning:
endless root) are particularly used extensively as a single drug and in formulations with
other plants to treat several ailments. In view of the wide range of medicinal properties
claimed in traditional medicine, significant efforts have been made to determine the
efficacy of Hemidesmus indicus through pharmacological experiments in vitro and in
vivo models. These include analgesic, anti-inflammatory, antipyretic, antioxidant,
antiarthritic, hepatoprotective, antiepileptic, anticonvulsant, antiulcer, antivenom,
antiacne, and antipsychotic activities. Recent studies have also established anti.diabetic, anti-carcinogenic, anti-venom, and wound healing activities. Extensive
phytochemical investigations have been carried out by several research groups. The
present review provides an overview of the bioactive compounds of this Indian
medicinal plant. Several classes of compounds, viz. triterpenoids, steroids, steroid
glycosides, coumarin-lignoids, flavonoids in addition to many simpler compounds,
have been isolated and characterised from different parts of H. indicus. These are
listed, along with brief write-ups on isolation procedures, spectroscopical and chemical
characterization, and their biological properties. Particular emphasis is given to the
anti-diabetic properties associated with it, indicus root extracts, and the factors
contributing to these properties
Reporte anual de visibilidad e impacto 2022
Authors: Fernández-Osorio Andrés Eduardo , Miron Marina
Published: September 2022

Este reporte compila los aportes académicos de la RCGJMC a la investigación y el debate sobre el uso legítimo del poder y su adecuado ejercicio en relación con los intereses nacionales, para el beneficio de la formulación de políticas y la gestión pública.
Removal of As(III) from Water by Cellulase Templated TiO2: A Photocatalytic Oxidation Conjugated Adsorption Process
Authors:   School of Engineering, National Center for International Research on Photoelectric and Energy Materials, School of Materials and Energy, School of Chemical Sciences & Technology, Yunnan University, Kunming 650091, P.R. China, Jiang Liang , Xie Lulu ,   School of Engineering, National Center for International Research on Photoelectric and Energy Materials, School of Materials and Energy, School of Chemical Sciences & Technology, Yunnan University, Kunming 650091, P.R. China, He Jiao ,   School of Engineering, National Center for International Research on Photoelectric and Energy Materials, School of Materials and Energy, School of Chemical Sciences & Technology, Yunnan University, Kunming 650091, P.R. China, Kang Juanxue ,   School of Engineering, National Center for International Research on Photoelectric and Energy Materials, School of Materials and Energy, School of Chemical Sciences & Technology, Yunnan University, Kunming 650091, P.R. China, Wang Wei ,   School of Engineering, National Center for International Research on Photoelectric and Energy Materials, School of Materials and Energy, School of Chemical Sciences & Technology, Yunnan University, Kunming 650091, P.R. China, Wang Jiaqiang ,   School of Engineering, National Center for International Research on Photoelectric and Energy Materials, School of Materials and Energy, School of Chemical Sciences & Technology, Yunnan University, Kunming 650091, P.R. China
Published: September 2022

TiO2 photocatalyst was prepared using cellulase as a biotemplate through a hydrothermal process. The as-prepared catalyst was characterized based on physicochemical techniques and was used to remove As(III) from contaminated water. The cellulase templated TiO2 photocatalyst (TiO2-cellulase) had a large specific surface area, which reached 166.6 m2·g–1. It also had a strong oxidation ability and, thus, behaved well in both photocatalytic oxidation of As(III) and dark adsorption. The pH of the solution had a negligible effect on the removal rate. TiO2-cellulase had a higher photocatalytic removal rate of As(III) than commercial Degussa P25 TiO2.
Assessment of lipid profile with HbA1c in type 2 diabetic Iraqi patients
Authors: Al-Shaheeb Sama , Kamil Hashim Husham , Kadhim Mohammed Athir , Abdulkareem Almashhadani Haider , Al Fandi Ali
Published: September 2022

Insulin-induced hyperglycemia is the hallmark of diabetes mellitus (DM), including various metabolic disorders. Diabetic people are more likely to develop dyslipidemia, hypertension, and obesity. Type 2 diabetes ‎(T2DM), the most common illness, is generally asymptomatic in its early stages and can go misdiagnosed for years. Diabetes screening may be beneficial in some cases since early identification and treatment can lessen the burden of diabetes and its consequences.‎ This study aimed to find the relationship between Glycated hemoglobin (HbA1c) ‎and lipid profile components in T2DM‎ patients. This descriptive-analytical and cross-sectional study was performed on the control group and T2DM patients in ‎Medical City in Baghdad between March and June 2021‎. A total of 90 patients with T2DM and ‎‎45 healthy control were included in this study. In the control group, healthy volunteer individuals participated. For all subjects, HbA1c, fasting blood sugar/FBS, and lipid profile (Total Cholesterol/TC, Triglyceride/TG, High-density Lipoprotein/HDL, Low-density Lipoprotein/LDL, and Very Low-density Lipoprotein/VLDL) were assessed. Among T2DM patients 62.22% (n= 56) were male and 37.78% (n= ‎‎34) were female. Mean ± SD levels of HbA1c, TC, TG, LDL, VLDL, HDL, and FBS were 7.33±0.56 ‎‎% (168.21±9.23, 146.10±9.64, 137.23±8.32, 41.05±5.86, 43.85±6.17, and ‎‎208.81±52.1) mg/dl respectively in the T2DM group. In the control group, ‎the Mean ± SD results of the same parameters were 4.91±0.27%, ‎‎(171.20±3.57, 116.60±8.25, 105.05±2.11, 41.83±4.92, 44.04±5.54, ‎‎96.20±7.8) mg/dl respectively. Results demonstrated statistically significant ‎‎differences between T2DM patients and control groups in HbA1c ‎‎(p equal to 0.0025), TG ‎(p equal to 0.015), LDL ‎ ‎(p=0.0029),‎ and FBS ‎(p=0.02‎). Pearson correlation analysis of HbA1c with other variables showed a significant ‎positive correlation with serum TC, TG, LDL, and ‎FBS ‎(r=0.573, P<0.01; ‎r=0.655, P <0.001; r=0.498, P<0.05‎; r=0.691, ‎P<‎0.001‎; ‎‏respectively). While the data showed a negative connection between HbA1c and HDL (r= - 0.562, P<0.01) The findings of this study reveal that diabetic people do not have a satisfactory HbA1c level. Furthermore, HbA1c shows a significant correlation with TC, TG, LDL, and VLDL, whereas it has a significant negative correlation with HDL. The study showed that HbA1c might be useful for predicting dyslipidemia in T2DM patients.

Keywords: T2DM, Lipid profile, HbA1c.
Levantamiento y evaluación del catastro del recurso hídrico en tres microcuencas del Río Sampile
Authors: Almendares-Rivera Kelly , García-Santos Saúl , Peña-Paz Tania , Chirinos-Escobar Marcio
Published: September 2022

Investigación basada en el levantamiento y análisis del catastro de fuentes de abastecimiento de agua para consumo humano presentes en tres microcuencas pertenecientes al Río Sampile en la zona sur de Honduras. Esta iniciativa nace ante la necesidad de tener en el país, y principalmente en el área de estudio, información hídrica de oferta, demanda, su condiciones sociales y ambientales. Para lograrlo, se analizó oferta, usando valores de parámetros climáticos, y estudios de descripción física, y para, el análisis de demanda y análisis del contexto social, ambiental y del agua, mediante campo, el catastro de fuentes de agua dentro de cada microcuenca en estudio, utilizando una ficha de levantamiento de información. Los resultados muestran una oferta hídrica con la valoración de precipitación, escorrentía, recarga y evapotranspiración, la demanda actual y futura, carece y proyecta carencia de cobertura en un 100% a la población, se identificó también, falta de personería jurídica de las juntas administradoras de agua, y amenazas como, presencia de ganadería, agricultura y zonas cafetaleras dentro de las microcuencas, zonas con susceptibilidad a inundaciones, sequías y deslizamientos, y carencia de análisis de calidad de agua. La investigación es una herramienta de gestión integrada de los recursos hídricos.

Palabras claves: fuentes de agua, catastro, oferta hídrica, abastecimiento, demanda hídrica, dinámica social, dinámica ambiental del agua
mHealth Apps Using Behavior Change Techniques to Self-report Data: Systematic Review
Authors: Aguiar Maria , Trujillo Maria , Chaves Deisy , Álvarez Roberto , Epelde Gorka
Published: September 2022

Background

The popularization of mobile health (mHealth) apps for public health or medical care purposes has transformed human life substantially, improving lifestyle behaviors and chronic condition management.

Objective

This review aimed to identify behavior change techniques (BCTs) commonly used in mHealth, assess their effectiveness based on the evidence reported in interventions and reviews to highlight the most appropriate techniques to design an optimal strategy to improve adherence to data reporting, and provide recommendations for future interventions and research.

Methods

We performed a systematic review of studies published between 2010 and 2021 in relevant scientific databases to identify and analyze mHealth interventions using BCTs that evaluated their effectiveness in terms of user adherence. Search terms included a mix of general (eg, data, information, and adherence), computer science (eg, mHealth and BCTs), and medicine (eg, personalized medicine) terms.

Results

This systematic review included 24 studies and revealed that the most frequently used BCTs in the studies were feedback and monitoring (n=20), goals and planning (n=14), associations (n=14), shaping knowledge (n=12), and personalization (n=7). However, we found mixed effectiveness of the techniques in mHealth outcomes, having more effective than ineffective outcomes in the evaluation of apps implementing techniques from the feedback and monitoring, goals and planning, associations, and personalization categories, but we could not infer causality with the results and suggest that there is still a need to improve the use of these and many common BCTs for better outcomes.

Conclusions

Personalization, associations, and goals and planning techniques were the most used BCTs in effective trials regarding adherence to mHealth apps. However, they are not necessarily the most effective since there are studies that use these techniques and do not report significant results in the proposed objectives; there is a notable overlap of BCTs within implemented app components, suggesting a need to better understand best practices for applying (a combination of) such techniques and to obtain details on the specific BCTs used in mHealth interventions. Future research should focus on studies with longer follow-up periods to determine the effectiveness of mHealth interventions on behavior change to overcome the limited evidence in the current literature, which has mostly small-sized and single-arm experiments with a short follow-up period.
Mental Health Mobile Apps in the French App Store: Assessment Study of Functionality and Quality
Authors: Carrouel Florence , du Sartz de Vigneulles Benjamin , Bourgeois Denis , Kabuth Bernard , Baltenneck Nicolas , Nusbaum Fanny , Burge Valérie , Roy Sylvain , Buchheit Sophie , Carrion-Martinaud Marie-Line , Massoubre Catherine , Fraticelli Laurie , Dussart Claude
Published: September 2022

Background

Approximately 800 million people, representing 11% of the world’s population, are affected by mental health problems. The COVID-19 pandemic exacerbated problems and triggered a decline in well-being, with drastic increase in the incidence of conditions such as anxiety, depression, and stress. Approximately 20,000 mental health apps are listed in mobile app stores. However, no significant evaluation of mental health apps in French, spoken by approximately 300 million people, has been identified in the literature yet.

Objective

This study aims to review the mental health mobile apps currently available on the French Apple App Store and Google Play Store and to evaluate their quality using Mobile App Rating Scale–French (MARS-F).

Methods

Screening of mental health apps was conducted from June 10, 2022, to June 17, 2022, on the French Apple App Store and Google Play Store. A shortlist of 12 apps was identified using the criteria of selection and assessed using MARS-F by 9 mental health professionals. Intraclass correlation was used to evaluate interrater agreement. Mean (SD) scores and their distributions for each section and item were calculated.

Results

The highest scores for MARS-F quality were obtained by Soutien psy avec Mon Sherpa (mean 3.85, SD 0.48), Evoluno (mean 3.54, SD 0.72), and Teale (mean 3.53, SD 0.87). Mean engagement scores (section A) ranged from 2.33 (SD 0.69) for Reflexe reussite to 3.80 (SD 0.61) for Soutien psy avec Mon Sherpa. Mean aesthetics scores (section C) ranged from 2.52 (SD 0.62) for Mental Booster to 3.89 (SD 0.69) for Soutien psy avec Mon Sherpa. Mean information scores (section D) ranged from 2.00 (SD 0.75) for Mental Booster to 3.46 (SD 0.77) for Soutien psy avec Mon Sherpa. Mean Mobile App Rating Scale subjective quality (section E) score varied from 1.22 (SD 0.26) for VOS – journal de l’humeur to 2.69 (SD 0.84) for Soutien psy avec Mon Sherpa. Mean app specificity (section F) score varied from 1.56 (SD 0.97) for Mental Booster to 3.31 (SD 1.22) for Evoluno. For all the mental health apps studied, except Soutien psy avec Mon Sherpa (11/12, 92%), the subjective quality score was always lower than the app specificity score, which was always lower than the MARS-F quality score, and that was lower than the rating score from the iPhone Operating System or Android app stores.

Conclusions

Mental health professionals assessed that, despite the lack of scientific evidence, the mental health mobile apps available on the French Apple App Store and Google Play Store were of good quality. However, they are reluctant to use them in their professional practice. Additional investigations are needed to assess their compliance with recommendations and their long-term impact on users.
The Development of Game-Based Digital Mental Health Interventions: Bridging the Paradigms of Health Care and Entertainment (Preprint)
Authors: Lukka Lauri , Palva J Matias
Published: September 2022

UNSTRUCTURED

Game elements are increasingly used to improve user engagement in digital mental health interventions, and specific game mechanics may yield therapeutic effects per se and thereby contribute to digital mental health intervention efficacy. However, only a few commercial game–based interventions are available. We suggest that the key challenge in their development reflects the tension between the 2 underlying paradigms, health care and entertainment, which have disparate goals and processes in digital development. We describe 3 approaches currently used to negotiate the 2 paradigms: the gamification of health care software, designing serious games, and purpose shifting existing entertainment games. We advanced an integrative framework to focus attention on 4 key themes in intervention development: target audience, engagement, mechanisms of action, and health-related effectiveness. On each theme, we show how the 2 paradigms contrast and can complement each other. Finally, we consider the 4 interdependent themes through the new product development phases from concept to production. Our viewpoint provides an integrative synthesis that facilitates the research, design, and development of game-based digital mental health interventions.
Editorial
Authors: Álvarez Plaza Consuelo , Machin Rosana , Blazquez Graf Norma , Salomé Lima Natacha
Published: September 2022

La reproducción asistida plantea muchos retos que deben debatirse de manera multidisciplinar. Si hace unas décadas el interés se centraba en los sujetos con necesidad de acceder a las técnicas de reproducción asistida, el derecho o no a conocer los orígenes genéticos, cuya consecuencia sería levantar el anonimato de los donantes, en la actualidad la reflexión gira en torno a quién debe elegir a los y las donantes, la cuota de niños nacidos por donante, la trazabilidad de las muestras y de los donantes, las posibles relaciones de los niños nacidos de donante y/o gestante con los donantes reproductivos y con los hijos “propios” de los mismos, lo que viene a ser la “hermandad genética”.

El dosier de este número abarca temas desde los mercados y flujos reproductivos entre Europa y América Latina; genética, donantes de ovocitos y semen; gestación por sustitución, familias y accesos; hasta debates en relación con las tecnologías reproductivas: discursos feministas y jurídicos.
lnvitamos a seguir este debate desafiante, y esperamos que el lector encuentre en nuestros trabajos una pequeña contribución a esta tarea colectiva de luchar por la justicia reproductiva, parte de la justicia social.
Reproducción transnacional con terceros: el mercado reproductivo en Brasil
Authors: Machin Rosana
Published: September 2022

La expansión de las tecnologías de reproducción asistida ha provocado un aumento en la movilidad de las personas y del material genético a escala mundial. El acceso a la fertilidad de terceros es característico de esta expansión. Este contexto incluye países con normativas y prácticas distintas que implican diferentes lógicas de movilidad de forma convergente, contradictoria e interdependiente. Es un mercado complejo, dependiente del trabajo reproductivo de las mujeres, sea remunerado o no. Para evaluar la situación del mercado de células sexuales en Brasil, se realizó un estudio con metodología cualitativa y análisis documental de los registros de importación de gametos. Se realizaron un total de 33 entrevistas semiestructuradas a profesionales de la salud reproductiva entre 2016-2018. Entre los principales resultados destacamos que la regulación médica adoptada en el país, la existencia de vacíos legales y la creciente demanda de gametos favorecieron el aumento de la importación de material genético procedente de bancos de semen en Estados Unidos y de bancos de óvulos en España. Los diferentes sistemas de regulación que operan en estos países fomentan el mercado de células sexuales al reforzar la lógica empresarial del poder de la oferta/demanda. 
El legado genético: mensajes de los donantes de semen a las familias y a sus descendientes
Authors: Álvarez Plaza Consuelo , Pichardo Galán J. Ignacio
Published: September 2022

La genética proporciona una cosmovisión emic del parentesco donde los gametos aparecen cómo portadores de vínculos y características heredables. Los mensajes personales de donantes de semen en las webs de los bancos señalan características que son percibidas por las receptoras como heredables. Objetivos: conocer los tipos de mensajes que dejan los donantes de semen en la web de un banco, a quiénes van dirigidos y cuál es el propósito de estos mensajes. Metodología: se realizó una etnografía virtual en la web oficial de un banco de semen danés, durante 2 meses en 2019. De 1,010 donantes registrados, el 60% (605), tenían en su perfil mensajes manuscritos visibles para los usuarios registrados. Resultados: los donantes de semen están clasificados por perfiles “raciales”: 915 (87%) caucásicos, 54 (5%) asiáticos, 42 (3%) hispanos, 32 (3%) de oriente próximo y 16 (2%) africanos. Han dejado mensajes: 531 caucásicos (seleccionados 100 para el análisis), 32 asiáticos, 41 hispanos, 17 de oriente próximo y 12 africanos. Los mensajes suelen incluir una descripción personal, las motivaciones para ser donantes y mensajes para los niños/as explicitando, en algunos casos, la posibilidad de contacto. Conclusiones: los mensajes son retratos personales de los donantes que pretenden motivar para ser elegidos y presentarse como alguien único. 
La no regulación de la gestación subrogada en México entre 2018 y 2021. ¿Laicismo o evangelismo?
Authors: Olavarría María Eugenia
Published: September 2022

Este artículo explora el contexto de la no regulación de la gestación por sustitución o gestación subrogada en México en los últimos tres años. A través de las iniciativas legislativas presentadas ante el Congreso de la Unión y las sentencias de la Suprema Corte de Justicia de la Nación durante 2021, este trabajo se pregunta si estas abonan o no al fortalecimiento del laicismo del Estado y en qué medida la visibilidad reciente de las asociaciones evangélicas y de los partidos de base confesional aportan en este sentido. Con base en la revisión del contenido de las propuestas de modificación a la Ley Federal de Salud por parte de la senadora Olga Sánchez Cordero del partido en el poder Movimiento de Regeneración Nacional (Morena), tanto como en el principal documento pedagógico del gobierno federal la Cartilla moral, se discuten los tres principales rasgos de la perspectiva religiosa: 1) afirmación del óvulo fertilizado como persona; 2) rechazo a la “ideología de género”, y, 3) la noción de familia natural. Ante el hecho de que la veintena de inicitativas presentadas desde 2011 ante las cámaras de diputados y senadores se encuentre en estatus ‘pendiente’, se concluye junto con especialistas médicos (Canales de la Fuente 2019, 13) y asociaciones civiles feministas (GIRE A. C. 2021, 332) que, a pesar de que desde hace más de cuatro décadas en México se realizan técnicas de reproducción humana médicamente asistida en clínicas y hospitales públicos y privados, hasta este momento no existe un marco normativo que permita garantizar el acceso a este tipo de atención, produciendo incertidumbre, riesgos para los involucrados y abriendo la puerta a posibles actos de discriminación. 