bluuebunny/crossref_metadata_2025 huggingface dataset:
Establishment and Application of a Quantitative PCR Method for E248R Gene of African Swine Fever Virus
Authors: Li Liwei , Du Nannan , Chen Jinxia , Zhang Kuan , Tong Wu , Zheng Haihong , Zhao Ran , Tong Guangzhi , Gao Fei
Published: August 2022

ASF has caused huge economic losses to China’s swine industry. As clinical symptoms of ASF were difficult to distinguish from classical swine fever and porcine reproductive and respiratory syndrome (PRRS), rapid and effective differential diagnosis of ASFV seems very important to control the spread of the disease. In this study, the ASFV E248R gene was selected to be the target for establishing a real-time PCR method. TaqMan real-time PCR for the detection of ASFV E248R gene did not cross-react with other porcine viruses that could cause similar symptoms. The results of the repeatability test showed that the coefficients of variation between and within groups were lower than 1.977%. This method can be used for the rapid detection and early diagnosis of ASF. Meanwhile, the recombinant PRRS virus (PRRSV)-expressing E248R gene of ASFV was constructed and rescued by using the reverse genetic platform of live-attenuated PRRSV vaccine. The ASFV E248R gene can be detected by using this real-time PCR detection method, confirming that the ASFV E248R gene could be stably amplified in PRRSV genome at least 20 cell passages. The detection methods can be used for the efficient detection of the ASFV infection and recombinant PRRSV live vector virus-expressing ASFV antigen protein.
Use of Maca Powder (Lepidium meyenii) as Feed Additive in Diets of Laying Quails at Different Ages: Its Effect on Performance, Eggshell Quality, Serum, Ileum, and Bone Properties
Authors: Gül Esra Tuğçe , Olgun Osman , Yıldız Alpönder , Tüzün Ahmet Engin , Sarmiento-García Ainhoa
Published: August 2022

Using additives can reduce the negative effects of aging on factors affecting profitability, such as the availability of nutrients, production, and egg quality. Maca is an herbaceous plant rich in protein, crude oil, essential acids, and pharmacological compounds. Maca has positive effects on different health parameters. In this study, the effect of adding Maca powder to the diets of young and old laying quails at the end of the 10-week trial was investigated. In total, 150 laying Japanese quails (Coturnix japonica) (209.1 ± 10.0 g) were randomly distributed to a 2 × 3 factorial arrangement with two ages (10 weeks and 30 weeks) and three Maca powder levels (0, 1, or 2 g/kg), with five subgroups per treatment. According to the study, eggshell quality, total cholesterol, triglyceride, progesterone, and testosterone concentrations of serum were lower in old quail than in young quail, while egg weight, feed intake, and follicle-stimulating hormone increased significantly as quail aged. (p < 0.05). Furthermore, aging negatively affected the histomorphology of the ileum and cortical bone thickness (p < 0.05). Additional findings show that adding 1 g/kg Maca powder to the diet of quail significantly improved eggshell, ileum, and bone traits that deteriorate with age, without affecting performance, and adding 2 g/kg Maca powder to the diet significantly reduced serum total cholesterol levels (p < 0.05). Incorporating Maca powder into the diet of aged birds could reduce the negative effects of aging.
What Is the Suitable Sampling Frequency for Water Quality Monitoring in Full-Scale Constructed Wetlands Treating Tail Water?
Authors: Song Siyuan , Sheng Sheng , Xu Jianqiang , Zhao Dehua
Published: August 2022

Three years of hourly COD and NH4+-N measurements for two full-scale integrated constructed wetlands (CWs) treating secondary effluents from sewage treatment plants (STPs) were used to quantify the proper sampling frequency (SF). The modified coefficient of variation (CVm) and average variation rate (VRa) were calculated to monitor the dynamics and annual average performance, respectively. It was found that (1) under CVm 5%, VRa 5%, and VRm 5%, the sampling intervals (SI) of COD can be set as 1.19 h, 526.5 h, and 110.1 h, respectively, and the SI of NH4+-N should be 4.51 h, 66.3 h, and 26.8 h, respectively; (2) under CVm 10%, VRa 10%, and VRm 10%, the monitoring intervals of COD can be set as 11.92 h, 1401.7 h, and 233.5 h, respectively, and the monitoring intervals of NH4+-N should be 30.73 h, 139.3 h, and 50.5 h, respectively. Therefore, to meet the need of monitoring the dynamic changes in data, hourly and 4 h SIs were recommended for COD and NH4+-N evaluation, respectively, when it is necessary to consider the operation and maintenance costs at the same time, 11 h and 30 h SIs were proper for COD and NH4+-N evaluation, respectively. The methods proposed in this study could provide reference to improve the management and evaluation level of full-scale CWs.
Nanomaterial-Based Sensors for the Detection of Glyphosate
Authors: Zúñiga Karem , Rebollar Georgette , Avelar Mayra , Campos-Terán José , Torres Eduardo
Published: August 2022

Due to its chemical properties, glyphosate [N-(phosphonomethyl)glycine] is one of the most commonly used agricultural herbicides globally. Due to risks associated with human exposure to glyphosate and its potential harmfulness, the need to develop specific, accurate, online, and sensitive methods is imperative. In accordance with this, the present review is focused on recent advances in developing nanomaterial-based sensors for glyphosate detection. Reported data from the literature concerning glyphosate detection in the different matrices using analytical methods (mostly chromatographic techniques) are presented; however, they are expensive and time-consuming. In this sense, nanosensors’ potential applications are explained to establish their advantages over traditional glyphosate detection methods. Zero-dimensional (0D), one-dimensional (1D), two-dimensional (2D), and three- dimensional (3D) materials are reviewed, from biomolecules to metallic compounds. Bionanomaterials have generated research interest due to their selectivity with respect to using enzymes, DNA, or antibodies. On the other hand, Quantum Dots also are becoming relevant for their vast surface area and good limit of detection values (in the range of pM). This review presents all the characteristics and potential applications of different nanomaterials for sensor development, bearing in mind the necessity of a glyphosate detection method with high sensitivity, selectivity, and portability.
Unsteady Friction Modeling Technique for Lagrangian Approaches in Transient Simulations
Authors: Zeidan Mohamad , Ostfeld Avi
Published: August 2022

This study investigates the simulation of celerity attenuation and head damping in transient flows using a Lagrangian approach rather than an Eulerian approach. Typically, the Lagrangian approach requires orders of magnitude fewer calculations, resulting in the rapid solution of very large systems. Additionally, it is based on a simple physical model. As the method is continuous in both time and space, it is less sensitive to the structure of the network and the length of the simulation process. Most recent studies, however, have focused on the development and improvement of computational routines for modeling in an Eulerian environment. This results in the development of adequate models that are suitable for Eulerian models but not applicable in Lagrangian-based models. As a result of this fixation, a bias was created towards using Eulerian approaches in transient simulations. It also diverts resources from further development of Lagrangian models. Consequently, it is necessary to develop a friction model that is more accurate and compatible with Lagrangian methods without compromising their performance. To the authors’ knowledge, such a model is yet to be published in the literature. This study presents a new friction modeling technique that compensates for both the local and convective acceleration terms for the Lagrangian transient modeling approach without compromising the computational time.
Research Progress on Integrated Treatment Technologies of Rural Domestic Sewage: A Review
Authors: Chen Peizhen , Zhao Wenjie , Chen Dongkai , Huang Zhiping , Zhang Chunxue , Zheng Xiangqun
Published: August 2022

The improvement of rural living standards in developing countries and the continuous upgrading of the rural industrial economy have prompted the diversification of rural areas and residential forms. Thus, an integrated rural sewage treatment process has gradually become the mainstream technology for rural sewage treatment. Numerous studies have reported the effects of ecological wastewater treatment. Meanwhile, the relevant process technologies, evaluations, and operating models of the integrated rural sewage treatment process have yet to be thoroughly summarized. This review aims to fill these gaps. First, the applicability of artificial wetland, soil infiltration, stabilization pond, and integrated rural sewage treatment process technology in rural sewage treatment are outlined and compared. Second, the process flow, technical characteristics, and economic indicators of typical integrated sewage treatment processes (i.e., Anoxic/Oxic (A/O) process, Membrane Bio-Reactor (MBR) process, biological contact oxidation process, Sequencing Batch Reactor Activated Sludge (SBR) process) are introduced. The engineering application effects of the integrated rural sewage treatment process in different countries are also described. Third, the practical and effective evaluation methods of the integrated rural sewage treatment process are introduced. Bearing in mind the current operation and maintenance management modes of the integrated rural sewage treatment process in developed and developing countries, combined with the national conditions of developing countries, the prospect section provides development proposals for further optimization and improvement of the integrated rural sewage treatment process in developing countries.
A Peridynamic Differential Operator-Based Model for Quantifying Spatial Non-Local Transport Behavior of Pollutants in Heterogeneous Media
Authors: Li Tianyi , Gu Xin , Zhang Qing
Published: August 2022

Modeling pollutant transport in heterogeneous media is an important task of hydrology. Pollutant transport in a non-homogeneous environment typically exhibits non-local transport dynamics, whose efficient characterization requires a parsimonious model with the non-local feature. This study encapsulates the non-local transport characteristic of pollutants into the peridynamic differential operator (PDDO) and develops a PDDO-based model for quantifying the observed pollutant non-local transport behavior. The simulation results show that the proposed model can describe pollutant non-local transport behavior in various heterogeneous media. The non-local nature of pollutant transport can be adjusted by pre-defined weight function w(|ξ|) and horizon Hx. Applications show that the PDDO-based model can better capture pollutant non-local transport behavior than the classical advection–diffusion equation (ADE) model, especially for quantifying the tail of the experimental data late. Analyses further reveal that the PDDO-based model can characterize both normal (Fickian) and anomalous (Lévy) diffusion regimes.
Impact of Boundary Conditions Dynamics on Groundwater Budget in the Campania Region (Italy)
Authors: Gaiolini Mattia , Colombani Nicolò , Busico Gianluigi , Rama Fabrizio , Mastrocicco Micòl
Published: August 2022

Groundwater budgets and fluxes are affected by human activities and climate change. Numerical models are cost-effective tools to investigate the different components of the hydrologic cycle. In this study, a groundwater flow model of the unconfined aquifers of the Campania region (Italy) has been developed and calibrated in Processing Modflow 11, resulting in an accurate assessment of groundwater fluxes and their trends over fifteen years (2000–2015). The model was implemented using a high-resolution grid to capture small hydrogeological features such as wells and rivers and informed by time variable datasets used as boundary conditions (i.e., river and sea levels, aquifer recharge, evapotranspiration, and discharge from adjacent systems). Good calibration and validation performances were achieved for piezometric heads (R2 = 0.958). A set of scenarios was developed using constant boundary conditions (i.e., constant sea-level BC, uniform extinction depth BC), and the outputs were compared, quantitively assessing differences in groundwater fluxes. Simulations pointed out that using time series to inform boundary conditions in the model does not always result in a significant change in the computed fluxes. Overall, non-uniform extinction depth was the most influential condition, while both rivers and sea level conditions barely affected groundwater budgets. In addition, results highlighted the need for an accurate estimation of spatiotemporal variations of both recharge and evapotranspiration, due to their strong seasonal variability and their massive contribution to the hydrogeological cycle. Finally, a marked increase of evapotranspiration fluxes controlled by interannual variability of precipitation and atmospheric temperatures has been quantified over the modelled period.
Assessing the Role of Extreme Mediterranean Events on Coastal River Outlet Dynamics
Authors: Meslard Florian , Balouin Yann , Robin Nicolas , Bourrin François
Published: August 2022

River mouths are highly dynamic environments responding very rapidly to changes in wave energy or river floods. While the morphological response during floods or during marine storm events has been widely documented in the literature, little is known about the mechanisms acting during the co-occurrence of fluvial and marine hazards. This concomitance of river flood and marine storm is quite common in the western Mediterranean Sea, and was the case for the Gloria event, considered to be the most extreme event in recent decades. During this event, monitoring of hydrodynamics and morphological evolution was implemented, making it possible to better understand the impact of concomitant marine storm and fluvial flood during an extreme meteorological event on spit breaching of a small Mediterranean river mouth. Monitoring using a combination of high-resolution hydrodynamic measurements, topographic and bathymetric surveys, and sediment cores was used before, during, and after the storm “Gloria”. The results suggest an amplification of the morphological impact of the events and a different morphogenic response than if each of the events had acted independently on the system. The marine storm, occurring first, weakened the spit and initiated its breaching, which was continued by the extreme fluvial flood, thus leading to the complete destruction of the mouth. The destruction of the spit acted as a sediment source for subaqueous large delta deposition amounting to 50% of the total volume. The contribution of the river, estimated at 30%, was quite low for an exceptional event, showing the importance of locating rainfall in a catchment area controlled by a dam. For this event, extreme morphological evolution was observed, as well as the importance of water levels in the river mouth, which probably increased flood hazards, demonstrating the importance of including the compounding effect of extreme coastal water levels in river flood risk management.
Determining the Flow Resistance of Racks and the Resulting Flow Dynamics in the Channel by Using the Saint-Venant Equations
Authors: Baselt Ivo , Malcherek Andreas
Published: August 2022

Racks retain debris in wastewater treatment plants and shield sensitive machinery in numerous engineering applications. In open-channel flows, racks impound the upstream water level by posing local obstacles in the flow. Based on experimental investigations, empirical approaches usually predict the flow resistance by relying on Bernoulli’s energy principle. Since this principle does not correctly consider downstream conditions such as submerged flows, we present a more accurate workflow to determine the flow resistance based on the Saint-Venant equations. We will demonstrate how the loss coefficient and the hydraulic head loss are determined more reliably without adding complexity to the engineering realisation. In contrast to relying solely on two cross-sections with Bernoulli’s energy principle, applying the Saint-Venant equations enables determining the flow depth profile and the flow velocity in the entire channel. This workflow additionally allows predicting the channel’s hydraulic capacity and freeboard in arbitrary applications.
Effects of Straw Mulching and Reduced Tillage on Crop Production and Environment: A Review
Authors: Du Changliang , Li Lingling , Effah Zechariah
Published: August 2022

Taking sustainable agriculture measures is critical to effectively cope with the effect of the increasing population on water shortage. Straw mulching and reduced tillage are the most successful measures adopted in arid and semi-arid regions which affect crop production by changing the crop environment. This review focuses on the effects of tillage and mulching on the soil environment, including soil organic matter, soil moisture, soil temperature, soil microorganisms, soil enzyme activity, soil fertility, soil carbon emissions, pests, weeds, and soil erosion. In addition, water use efficiency and crop production are discussed under different tillage measures. Straw mulching can increase soil organic matter content, adjust soil moisture, and prevent water loss and drought; however, it can also lead to an increase in pests and diseases, and change the structure of the soil microbial community. Straw mulching can significantly enhance WUE (water use effectively) and yield. Reducing tillage maintains soil integrity, which is conducive to soil and water conservation, but could negatively impact crop yield and WUE. Precise field management measures, taken according to crop varieties and local conditions, not only ensure the high yield of crops but also protect the environment.
Simulation-Based Evaluation of Charging Infrastructure Concepts: The Park and Ride Case
Authors: Fischer Markus , Hardt Cornelius , Elias Jörg , Bogenberger Klaus
Published: August 2022

In this study, a framework regarding park and ride facilities is presented and demonstrated to evaluate different approaches of charging concepts. The innovation in this study is that the framework can be used to evaluate arbitrary conductive charging concepts on a detailed level and on the basis of real usage data. Thus, the results can be broken down to the level of individual charging events and charging points. Among other factors, the study considers the expected growth in electric vehicles, the construction and operating costs for the investigated charging infrastructure, and the impact of heterogeneous electric vehicle fleets with different vehicle-specific charging powers. Since both technological and economic perspectives are considered in the framework, the study is relevant for all decision makers involved in the development and operation of charging infrastructure. The results in the investigated case of park and ride facilities show a high potential for cost-efficient low-power charging concepts. Thus, significantly higher energy volumes could be transmitted and better economic results could be achieved by the investigated low-power approaches. Especially for heterogeneous electric vehicle fleets, the number of available charging points appears to be more important than the charging power of the individual charging points in this case.
Rearing of quails for meat when over intermittent lighting different modes
Authors:   Federal State Budgetary Educational Institution of Higher Education “Russian State Agrarian University – Moscow Timiryazev Agricultural Academy”, Russia, Moscow, Osmanyan A. K. , Slashcheva Yu. V ,   Federal State Budgetary Educational Institution of Higher Education “Russian State Agrarian University – Moscow Timiryazev Agricultural Academy”, Russia, Moscow, Komarchev A. S. ,   Federal State Budget Scientifi c Institution Federal Scientifi c Center “All-Russian Research and Technological Poultry Institute” of Russian Academy of Sciences, Russia, Moscow region, Sergiev Posad
Published: August 2022

Poultry farming is currently the most dynamic and important branch of agricultural production in most countries of the world, including Russia. It is necessary for the development of the poultry industry to fi nd ways to increase the effi ciency of the use of production resources. The rejection of natural lighting and the widespread use of windowless poultry houses in industrial poultry farming by increasing the role of artifi cial lighting, made it possible to develop modes for regulating the puberty of poultry, manage the daily rhythm of egg laying, increase poultry productivity by reducing energy costs. The purpose of the research was to determine the best variant of intermittent lighting mode when testing two modes with decreasing light day and with decreasing-increasing light day when rearing meat and egg quails. The results of studies of intermittent lighting during the day during the rearing of the meat-egg quails up to 6, 7 and 8 weeks of age have been presented in the experiment. It was found that the most effective lighting mode with a decreasing-increasing light day at the age of quails of 3–4,4–5 and 5–8 weeks according to the scheme 10L:1D:10L:3D, 7L:2D:7L:8D, 9L:2D:9L:4D (L is the period of light, D is the period of darkness). As has been shown by the productivity index, depending on the fi nal live weight, livability, feed intake per 1 kg of gain and the age of the quails at slaughter, in the group with the specified light mode, the production effi ciency was the highest, in comparison with other groups. The level of profi tability of quail meat production was 73,2 % observed when rearing quails with the specified light mode up to 6 weeks of age, 53,0 and 31,7 % when rearing for 7 and 8 weeks, respectively. Rearing quails up to 6 weeks of age is economically more efficient than rearing up to 7 and especially up to 8 weeks of age.
Dinamika Penyebaran Agama Islam di Kerajaan Siantar, 1904-1913
Authors: Ponja Dona , Siregar Yusra Dewi , Azhar Anang Anas
Published: August 2022

This article discusses the dynamics of the spread of Islam in the Siantar Kingdom at the beginning of the 20th century. The interaction of coastal communities with inland areas through trade routes made this area then influenced by Islam. This study uses the historical method in four writing steps, namely; heuristics, verification or criticism, interpretation, and historiography, with a historical approach. After King Sang Naualuh Damanik embraced Islam, the development of Islam in this area spread quite massively. The king and the preachers and other court officials became the front guard in preaching Islam in Siantar. In the process of spreading, Islam also faced some serious challenges. First, there are still many Siantar people who embrace the religion of their ancestors (Habonaron Do Bona). Second, the entry of Christian missionaries from the RMG (Rheinische Missions Gesellschaft) organization from Germany, which was tasked with evangelizing the people of Simalungun and the coast of Lake Toba. With his increasingly active activities in preaching Islam, finally, Raja Sang Naualuh Damanik was arrested by the Dutch colonialists in 1905. The following year, he was exiled to Bengkasli, Riau. After the exile of the King, the spread of Islam in the Siantar region practically stopped.
Masjid Al-Musannif: Lambang Keberagaman di Kota Medan
Authors: Fitri Mita Saskia , Siregar Yusra Dewi , Abidin Syahrul
Published: August 2022

This article discusses the architecture of the Al-Musannif Mosque which is located in the Cemara Asri complex, Medan. Al-Musannif Mosque is one of the most famous mosques in Medan City. This study uses a qualitative research method with a descriptive approach. Al-Musannif Mosque is a mosque founded by one of the well-known businessmen in the city of Medan named H. Anif Shah. This mosque was founded after H. Anif Shah experienced a spiritual incident during the pilgrimage. This mosque comes with a domed architectural design, which combines various cultures in its architecture, such as: Malay, Arabic, and European. This mosque has a large courtyard, and is often used as a place to carry out religious and social activities. Until now, the Al-Musannif Mosque is one of the mosques that is often visited by residents of the city of Medan.
Komunitas Historical Sumatera Utara dan Perannya dalam Mempromosikan Situs Islam di Sumatera Utara, 2016-2021
Authors: Hasibuan Yudi Pratama , Achiriah Achiriah , Nurhayani Nurhayani
Published: August 2022

This article aims to discuss the History of the Historical Community of North Sumatra and its role in promoting Islamic sites in North Sumatra. The North Sumatra Historical Community was established on January 17, 2016. This community is a community engaged in history, education, tourism and culture. The members of this community are approximately 20 people. The method used in this research is the historical method with four stages, namely; heuristics, criticism or verification, interpretation and historiography. Based on the results of research that the authors get. The efforts made by the Historical Community of North Sumatra in carrying out its role as an institution that promotes Islamic sites in North Sumatra are; holding seminars and discussions, being a tour guide, promoting various historical sites through social media.
Analisis Signifikansi Taman Merdeka Kota Metro sebagai Objek Struktur Cagar Budaya
Authors: Amboro Kian
Published: August 2022

This article aims to identify and analyze the Taman Merdeka Kota Metro as the object of the cultural heritage structure. This research uses a descriptive qualitative method, with historical and archaeological approaches. The results showed that the Taman Merdeka Kota Metro met the criteria for cultural heritage as stated in Article 5 and Article 8 of the Law of the Republic of Indonesia Number 11 of 2010 concerning Cultural Heritage. The criteria that are met are: a) over 50 years of age; b) represents a style period of at least 50 years; c) has a special meaning for history and education; d) have cultural values for strengthening the nation's personality; e) have a single element and become one unit with the urban spatial landscape; f) its placement is integrated with natural formations. So based on historical and archaeological perspectives, it can be concluded that Taman Merdeka Kota Metro deserves to be proposed for its status as a Cultural Heritage Structure.
Peran Museum Perjuangan TNI dalam Merawat Peninggalan Karya Juang Prajurit di Kota Medan
Authors: Ginting Trimahdalena , Monang Sori , Devianty Rina
Published: August 2022

This article discusses the role of the Museum Perjuangan TNI in caring for the relics of the struggle of the Indonesian independence fighters in Medan and its surroundings. This article uses a historical research method with five steps, namely: topic selection, source collection, source criticism, interpretation, and historiography, with a qualitative approach. The main focus of this article is that the author wants to see the history of the establishment of the Museum Perjuangan TNI and the role it has in storing and caring for historical objects used by the fighters in Medan. Before becoming a museum, the building belonged to a Dutch insurance company named NV Levensverzekering Maatschappij Arnhem. After the Dutch surrender to Japan, the building was later converted into the headquarters of the Japanese army (Kementai). After being controlled by the Indonesians, this building was used as the office of the Commander of the Military Command (Pangdam) I-III. However, since October 5, 1996, this building was inaugurated as the TNI Struggle Museum by the Commander of the I/BB Regional Military Command, Major General (Mayjend). Sedaryanto. Currently the Museum Perjuangan TNI is located at Jalan KH. Zainul Arifin No. 8, Central Petisah Village, Medan City, North Sumatra Province. This museum acts as a place for education, tourism, and collective memory storage of the freedom fighters in Medan and its surroundings.
Masjid Jaya Ar-Rahman Bingai: Sejarah dan Perkembangannya
Authors: Ramadhani Annisa , Rohani Laila , Abidin Syahrul
Published: August 2022

Artikel ini membahas tentang sejarah dan perkembangan Masjid Jaya ar-Rahman Bingai yang merupakan masjid bersejarah peninggalan Kejuruan Bingai. Artikel ini menggunakan metode penelitian sejarah dengan pendekatan kualitatif. Fokus utama artikel ini ialah melihat bagaimana sejarah dan perkembangan Masjid Jaya ar-Rahman Bingai, terutama dalam bidang sosial dan keagamaan di sekitaran Langkat dan Bingai. Masjid ini didirikan oleh Tengku Abdul Rani bergelar Kejeruan Sri Amar Setia pada tahun 1889 M. Masjid ini berarsitektur Melayu dan menjadi salah satu masjid tertua yang ada di Kabupaten Langkat. Pada masa lalu, masjid ini menjadi pusat kegiatan keagamaan dan sosial di wilayah Bingai. Bahkan, masjid ini juga dijadikan sebagai tempat bermusyawarah para pembesar Kesultanan Langkat dan Kejuruan Bingai. Posisi masjid ini menghadap ke arah Sungai Wampu dan sering dijadikan sebagai tempat transit para pedagang yang melewati sungai tersebut. Saat ini kondisi masjid tersebut masih berdiri kokoh dan tetap menjadi ikon kebanggaan masyarakat Langkat umumnya, dan masyarakat Bingai khususnya.
Innate Immunity and SARS-CoV-2 Vaccine Response in Hemodialysis Patients
Authors: Valentini Nicolas , Marchitto Lorie , Raymond Maxime , Goyette Guillaume , Kaufmann Daniel E. , Finzi Andrés , Suri Rita S. , Lamarche Caroline
Published: August 2022

Key Points

Patients receiving hemodialysis (HD) have more inflammatory monocytes and less plasmacytoid dendritic cells (DCs) compared with healthy controls.

Patients on HD who have a poor antibody response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine had fewer monocyte-derived DCs and conventional DCs compared with good responders.

The defects in antigen presentation might be possible therapeutic targets to increase vaccine efficacy in HD patients.
Land objects size approximation informational technology
Authors: Zhernovyi V.
Published: August 2022

Despite rapid development of Big Data and data processing technologies, it is still quite a challenge to implement efficient pipelines for obtaining reliable and reasonable results. In re-mote sensing, thousands of gigabytes of data is acquired by satellite and aircraft vehicles, but only the modest amount of data is processed. Among the data processed, even less results re-mains reliable overtime due to the nature of satellite imagery. Nowadays, machine learning area affects nearly every domain of knowledge including remote sensing. A toolset of machine learning suggests ways to automate data processing which makes data pipelines constructure much more effective. Deep neural networks demonstrate the best results so far in image pro-cessing field. However, applying deep learning achievements in Remote Sensing still remain challenging in regard to multi-channel satellite imagery of a very-high resolution. Despite astonishing results deep learning field demonstrates in remote sensing competitions such as Open Street Map, these are applicable on regular RGB images of popular image formats such JPEG and similar. In current paper, a technology is suggested to apply deep neural network toolset in multispectral images of a very high resolution acquired from a commercial WorldView-3 satellite vehicle. The suggested approach covers topics of dataset preparation to fully replicate the results of the suggested neural network training. The proposed neural network solution output are segmentation maps. In addition to replicatable neural network structure, a particular use case is considered in detail which implements a fully automated technology of highly precise approximation of physical sizes of the land objects. The neural network performance is measured and compared to modern similar neural network solutions.
Web application for researching the brightness distribution of pixels in digital images
Authors: Ivon A. , Istushkin V. , Krikunenko Yu.
Published: August 2022

Web application (program) for testing the distribution of pixel brightness along the line segment specified by user on a digital image is described. The application was created using the languages HTML5, CSS3, JavaScript and the Canvas technology. Investigations of the pixels brightness distribution of digital images of analog oscillograms were performed. On the basis of these investigations the criteria necessary for organizing automatic (software) scanning of the oscillograms digital images at measuring the parameters of electric signals were determined.
Simulation modeling of a computer system multithreaded architecture using AnyLogic
Authors: Gnilenko A.
Published: August 2022

The simulation is the most effective way to investigate information processing in computer systems. Computer system simulation is advantageous due to the fact, that such class of systems are well formalized in the form of queuing systems. Any computer system can be considered in terms of queuing system theory as an interconnected set of requests for service, system re-sources, queues to resources, and rules of service. The problem with the study of computer systems is that the existing simulation software tools have been developed as universal tools for the study of general-purpose systems. There are no specialized libraries or separate modeling tools for the study of computer systems. Therefore, modeling computer systems based on the use of standard libraries of such a modern modeling tool as AnyLogic, and the possible creation of elements of a specialized library is of great importance. The objective of the paper is to model multithreaded computing in a multiprocessor computer system using AnyLogic software. The designed computer system diagram enables us to have a deep insight into all details of information processing, and the obtained characteris-tics of the computer system, such as CPU usage coefficients, queue dynamics, distribution of thread execution time in the system, etc., allow us to determine the most effective configuration of the system, the parameters of its elements and operation modes.
Methods for detecting statistical changes in network traffic characteristics
Authors: Astakhov D. , Mazurenko V. , Fedorovych A. , Lysenko N.
Published: August 2022

Network flows of information systems (IS) are characterized by certain quantitative characteristics. They contain information about network load, the quality of communication between nodes, and many other service information. For example, an attacker can use this service information to prepare for a cyberattack. When an attack is already being carried out, network traffic is filled with additional atypical information. In other words, the values of its quantitative characteristics change. Therefore, quantitative indicators of these characteristics can indirectly monitor the atypical behavior of network nodes. For example, by the number of requests of the same type per unit of time. Such an event may occur, for example, when the network scanner is running or during a denial-of-service attack. To detect such events, special software packages are used, such as intrusion detection systems. These systems use a variety of algorithms in their work, which are based on statistical methods, neural networks, fuzzy logic Automata, and others. The type of mathematical processing depends on the complexity of the problem, the level of the protocol being observed, and the preferences of the detection system developer. Sometimes statistical methods for analyzing metrics can be simpler and faster to implement than others, because they do not contain a large number of mathematical operations. This can allow you to monitor the state of the IP in real time. And timely detection of changes in the state of the IP allows you to avoid malfunctions. One of the signs of a change in the system state is the release of values of quantitative indicators of network traffic parameters. Therefore, this task is urgent and requires further development and improvement. In this paper, it is investigated that using the Chauvet criterion, it is possible to detect outliers with high probability in small time series with a probability distribution that differs from the normal one.
Detecting fishing URLs using fuzzy clustering algorithms with global optimization
Authors: Gerasina O. , Korniienko V. , Gusev O. , Sosnin K. , Matsiuk S.
Published: August 2022

An algorithm for detecting phishing URLs (classifier) using fuzzy clustering is proposed, which includes choosing the type of intelligent classifier and justifying its parameters using global optimization methods. The following were studied as intellectual classifiers: subtractive clustering and fuzzy clustering of C-means. To find (adjust) the optimal (for a specific task) parameters of intelligent classifiers, the use of global optimization methods is justified, including genetic algorithm, direct random search, annealing simulation method, multicriteria optimization and threshold acceptance method. As a criterion of global optimization, a combined criterion was used, which includes the definition of the regularity criterion calculated on the test sample and the bias (minimum shift) criterion based on the analysis of solutions. By modeling in the Matlab environment with the help of standard and developed programs, the evaluated efficiency of using the proposed algorithm is evaluated on the example of experimental data – a set of 150 phishing and 150 secure URLs. The set of experimental data included information about the domain name registrar, the lifetime of the domain, the geolocation of the hosting server, the presence of a secure connection with a valid certificate. By simulation it is established that the fuzzy classifier with the subtractive clustering algorithm and using the Sugeno structure and 6 clusters meets the minimum of the combined criterion. All phishing URLs that were mistakenly classified as secure were found to have a secure con-nection with a valid certificate. Thus, further research should be aimed at exploring additional informative attributes (features) that could allow better separation of phishing and secure URLs.
Development of a parametric model of a building of the educational institution in the OpenSCAD system
Authors: Uzlova M. , Zhurba A. , Zhuravlev V. , Larionov H.
Published: August 2022

Not so long ago, the production of master models and prototyping was a complex and difficult process, prototypes were made by hand on the basis of complex developments and drawings. Now, with the advent of 3D technology, these processes have become much simpler and much more efficient. 3D modeling plays an important role in the life of modern society. 3D graphics are widely used in marketing, architecture, design and many other areas. 3D modeling is a limitless possibility. Three-dimensional models, animation, visualization - a generalized, but far from complete list of possibilities. 3D modeling allows you to create a prototype of a future building, a commercial product in three-dimensional format, printed on a 3D printer. The use of three-dimensional models of real objects is an unusual and interesting means of transmitting information, which can significantly increase the effectiveness of the presentation. OpenSCAD software was selected to perform the work. This open 3D modeling program allows the designer to model quite complex and accurate 3D models and parametric structures that can be easily adjusted by changing the parameters, the simulation itself is based on a program written in OpenSCAD. Therefore, the topic of the work "Development of a parametric model of a building of the educational institution in the OpenSCAD system" is relevant. The purpose of this work is to develop a parametric model of the building of the Ukrainian State University of Science and Technology using the OpenSCAD system.
Research and development of the method design UX / UI design internet – platforms
Authors: Ostrovskaya K. , Guda A. , Romanyuk K.
Published: August 2022

The work is devoted to interface design using the developed methodology. The paper considers the issues of developing a methodology to improve the quality of development of online stores and speed up this process. The purpose of the work was to research and develop a methodology for designing UX / UI design of an Internet platform. As a result of the work, a study was made of the design process of the user interface of the Internet platform. A methodology for designing the interface of an online store has been developed, which helps to develop a product with high quality. The main approaches to designing user interfaces were considered, studies of existing UX research methods were carried out and the most popular of them were applied. A methodology for designing the interface of an online store was developed. To evaluate the effectiveness of the created methodology, the ranking method and the network analysis method were used. As a result of an experimental study of the proposed methodology, the values of the concordance coefficient were found, which indicate a sufficient degree of agreement of opinions. Also, based on the results obtained by the network analysis method, it can be concluded that the second design option is the most preferable (global priority = 0.612). An economic justification for the feasibility of this work has been carried out.
Concept of digital voting based on the Blockchain technology
Authors: Volkovskyi O. , Pachevskyi M. , Obydennyj E.
Published: August 2022

Democratic voting is one of the most popular methods of resolving socially important issues in developed countries. The most common method of voting is the paper system. This method has certain disadvantages, including technical (falsifications, calculation errors, lack of transparency), social and economic (high cost to the budget). Electronic voting systems have not become widespread due to security issues, verification of results or incorrect operation of software [1, 2]. Blockchain technology offers new opportunities to develop completely different types of digital services due to the key features of this technology, such as transparency and security of the data transfer process. Developers have the opportunity to bring the voting system to a new information technology level that meets modern requirements. The use of smart contracts in combination with blockchain technology will help solve most of the existing problems of modern voting systems Blockchain technology is based on a transactional model. The principle of operation of blockchain technology is shown in Pic. 1. Each user has his "wallet" with unique public / private keys, which confirm any action of the user. Transactions (agreement, shipment), which are carried out by all users of the system, are stored in successive blocks. Since the hash of the data of the previous block is used when generating the next, the consistency of the data within the blockchain is ensured.
Decision support system for the use of metal in multi-stage rolling production
Authors: Zheldak T. , Koriashkina L. , Haranzha D. , Serdiuk D.
Published: August 2022

The presented system is based on the implementation of a mathematical model of the problem of optimal metal consumption in a two-stage process of its distribution in the produc-tion of rolled products, namely: at the stage of casting steel from a ladle during converter production and during the formation of blanks in machines with continuous casting. The cri-terion of optimality is the minimum loss of metal. This takes into account the type of products produced and possible options for cutting in two rolling stages. The mathematical model is a problem of partial-integer linear programming. For its solving, we use the method of branches and boundaries. An important part of the DSS is the preprocessing of a large order containing various types of products and providing for the execution of several heats. The proposed heuristic algorithm for dividing a large order into parts that can be performed within only one heat with as complete filling of the ladle as possible. Moreover, the received order, measured in tons, is converted into that measured in the bars of the finished product. The presented results of computational experiments confirm the correctness of the mathematical model of the problem of optimal metal distribution when fulfilling the plan for the production of rolled products. The presented calculations also show the possibility of using the developed system at metallurgical enterprises in the production of rolled products to ensure the minimum number of changeovers of the equipment of cutting machines and the rational use of metal.
Automation of solving problems of optimization of parameters of metrological maintenance system of measuring equipment
Authors: Ignatkin V. , Alekseyenko S. , Gorbiychuk M.
Published: August 2022

Automation of the metrological service of the enterprise allows to reduce the use of labor to perform tasks of maintenance of measuring equipment and reduce staff errors. At the same time, the process of creating appropriate automated systems requires solving a number of problems related to the need to optimize the parameters of the designed system to ensure its highest efficiency. This article attempts to solve the problem of covering various models in the synthesis and study of simulation computer models that actively use the database of measuring instruments of enterprises. Developed and software implemented a model that allows interactive mode, taking into account the characteristics coming from the calibration laboratories of the service, and given economic and metrological criteria, to determine the values of optimal calibration and repair intervals, the optimal number of inspections in the repair interval and other parameters. The dependence of FTA reliability indicators on the quality of metrological maintenance and repair was investigated by simulation. The influence of inter - repair and inter - calibration intervals on economic efficiency of metrological service is investigated. As a result, the dependences are obtained, which also allow to investigate the influence of service quality parameters on complex reliability indicators. The use of research results allows in the dialog mode of the automated workplace of the metrologist to solve problems of optimization of parameters of metrological service on eco-nomic criteria and restrictions of concrete production on indicators of metrological reliability of measuring instruments, to carry out diagnostics and to forecast metrological reliability of measuring instruments. measurement accuracy and reduce the likelihood of hidden failures.