bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring the potential therapeutic value of Solanum lycopersicum L. phytoconstituents for Parkinson's disease through molecular docking analysis
Authors: Rani Khan  , Divyam Maheshwari  , Sunny Chauhan  , Gopal Vijay Lohiya  , Chandan Kumar  , Ishika Antil  , Shalu Sharma  , Yashika Garg  , Prince Chauhan  , Shamim  , Sudhanshu Kumar Jha
Published: November 2023

Parkinson's disease is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the brain, leading to motor and non-motor symptoms. The search for novel therapeutic agents to mitigate the progression of the disease and alleviate its symptoms has led to the exploration of natural compounds. Solanum lycopersicum L., commonly known as tomato, contains various phytoconstituents that have shown promise in neuroprotection and anti-inflammatory properties. This study aims to investigate the potential therapeutic value of Solanum lycopersicum L. phytoconstituents for Parkinson's disease through a comprehensive molecular docking analysis. Using state-of-the-art computational techniques, we will evaluate the binding interactions between these phytoconstituents and key protein targets associated with Parkinson's disease. The findings from this research may contribute to the development of new therapeutic strategies and drug candidates for the management of Parkinson's disease.
Die Käferfauna (Coleoptera) des Greifensolls bei Greifswald in Vorpommern
Authors: Wendlandt Leopold , Mainda Tobias
Published: November 2023

Von 2019 bis 2022 wurde die Käferfauna eines Kleingewässers am südlichen Stadtrand von Greifs-
wald in Vorpommern (54°03’48.3”N 13°22’41.4”E) untersucht. Dieses Kleingewässer wird erstmals als
Greifensoll benannt und beschrieben. Das Greifensoll ist hydrologisch durch jahreszeitliche Wasser-
standsschwankungen mit unregelmäßigem Trockenfallen im Sommer gekennzeichnet. Die Vegetation
des Gewässers wird von großen Beständen des Breitblättrigen Rohrkolbens (Typha latifolia L.) und der
Wasser-Sumpfkresse (Rorippa amphibia (L.) Besser) dominiert. Die am häufigsten angewandten Un-
tersuchungsmethoden waren das Aufsammeln per Hand und der Fang aquatischer Käfer mit Küchen-
sieb und Wasserkescher. Insgesamt wurden 204 Arten nachgewiesen, darunter 82 Arten aquatischer
Käfer aus neun Familien und 101 Arten terrestrischer Käfer aus zwölf Familien, inklusive 21 Arten der
Steninae (Staphylinidae). Bemerkenswert sind die Nachweise der gefährdeten Schwimmkäfer-Arten
Agabus labiatus (Brahm, 1790), Graptodytes bilineatus (Sturm, 1835), Hydroporus fuscipennis Schaum,
1868 und Rhantus bistriatus (Bergsträsser, 1778), des Hakenkäfers Dryops griseus (Erichson, 1847) so-
wie der Kurzflügelkäfer Stenus melanarius Stephens, 1833 und S. sylvester Erichson, 1839. Der Schim-
melkäfer Telmatophilus sparganii (Ahrens, 1812) wird das zweite Mal überhaupt für Mecklenburg-
Vorpommern gemeldet und der Triebstecher Temnocerus coeruleus (Fabricius, 1798) das erste Mal nach
2000. Das Greifensoll repräsentiert mit seiner hohen Artenvielfalt ein regional bedeutsames Habitat
in einer intensiv genutzten Agrarlandschaft.
Development of Obstacle Detection System Based On the Integration of Different Based Sensor for Small-Sized UAV
Authors:   Universiti Tun Hussein Onn Malaysia (UTHM), Nawawi Muhammad Amirul , Ramli Muhammad Faiz ,   Universiti Tun Hussein Onn Malaysia (UTHM)
Published: November 2023

Due to the physical size and weight limits of small unmanned aerial vehicles (UAVs), developing a reliable obstacle detection a system that can provide an effective and safe avoidance path is extremely difficult. Prior work has tended to use a vision-based sensor as the primary detecting sensor however, this has resulted in a high reliance on texture appearance and a lack of distance sensing capabilities. Furthermore, due to the inability to detect the free region, vision-based sensor detection systems have difficulty developing a trusted safe avoidance path. However, most wide spectrum range sensors are bulky and expensive, making them unsuitable for small UAVs. This projectaims to construct an obstacles detection system with the integration of various based sensors for a small UAV. The potential obstacles are identified by categorizing feature points identified in image frame. The suggested approach was tested in a real-world setting for both of the observed scenarios, which included various obstacles configurations. Two types of scenarios are experimented in this project consists of single frontal obstacles and presence of side obstacles alongside the frontal obstacles. On top of that, the position of the side obstacle is aligned to the frontal obstacle and then will be positioned in the increment of 20cm further from the frontal obstacle in order to analyze the outcome of the proposed algorithm. The proposed detection system had a possibility to be a trustworthy system even after utilizing the depth perception technique, however this does not imply that the proposed system is faultless. The results show that the suggested algorithm system detects and distinguishes between the potential obstacles and free region for a single frontal obstacle perfectly. However, there were improvements that should be implemented with the proposed system's ability of detection for multiple obstacles.
Mechanism System to Reduce the Pendulum Effect of a Load for Delivery Drone
Authors:   Universiti Tun Hussein Onn Malaysia, Abd Wahid Amirul Hilman bin , Ramli Muhammad Faiz Bin ,   Universiti Tun Hussein Onn Malaysia
Published: November 2023

Unmanned aerial vehicles (UAVs), also referred to as "drones," are becoming more widely accepted as a typical form of transportation for a range of purposes in the logistics sector. Drones are anticipated to outperform traditional vehicles in a number of ways, including with a constant, quick speed, travel is straightforward, there is no exposure to traffic, and there is no requirement for physical transportation infrastructure. When an aircraftis in a sideslip, these surfaces generate sideward lift forces, which is known as the pendulum effect. The keel effect, also known as the "Pendulum Effect," occurs when the effect of sideways forces above the center of gravity in producing a rolling moment is increased by having a lower center of gravity. The load shift, also known as the pendulum effect, reduces flight efficiency and may unbalance the UAV, resulting in catastrophic failure. The purpose of this project is to construct a mechanism system toreduce the pendulum effect of a load for the delivery drone and to investigate the numbers of pendulum sway with the different types of loads. The mechanism for this project was constructed by using a 3D printer. The experiment process was used to carry out this project. This project's variables included various types of loads, string length, and the number of sways. The data obtained in this project are important to determine which design is the best for the delivery drone. Unfortunately, the data from the experiment gave the same result for all designs. For future studies try to come up with new concepts for how to construct the mechanism system to reduce the pendulum effect of a load for delivery drone and compare all the concepts.
Caracterización Eléctrica de una Pinza Bioinspirada
Authors: Estrada Cabrera Alan Jesús , Tecpoyotl-Torres Margarita , Vargas-Chable Pedro , Cabello-Ruiz Ramón
Published: November 2023

Este trabajo se enfoca en una micropinza bioinspirada, normalmente abierta, que corresponde al campo de los sistemas microelectromecánicos, MEMS, así como en el escalamiento del dispositivo y su proceso de fabricación en aluminio 6053 para la realización de pruebas de desempeño. El diseño está inspirado en las mandíbulas de las hormigas. Su estructura se compone de un amplificador flexible de tipo M y un actuador chevrón con vigas de forma Z. El diseño y la simulación se realizaron con ANSYSTM. Se calcularon la resistividad del aluminio y la resistencia equivalente de la pinza, y se realizaron pruebas experimentales con un medidor de propiedades eléctricas de inductores (L), capacitores (C) y resistencias (R), LCR. Se realizó la caracterización experimental de la pinza, aplicando un barrido de corriente eléctrica desde 5 hasta 60 A al actuador. Los valores de temperatura se registraron mediante una cámara termográfica; el desplazamiento se determinó con un microscopio. El error promedio entre los resultados numéricos y experimentales de la temperatura de la flecha del actuador son menores al 13%.
Detección del uso de casco de seguridad en imágenes de trabajadores mediante el método de la bolsa de palabras visuales (BoVW)
Authors: Cortes Aguilar Teth Azrael , Tovar Arriaga Adriana
Published: November 2023

El casco de seguridad es un equipo de protección personal (EPP) imprescindible para prevenir accidentes fatales en fábricas y sitios de construcción. El problema es que en muchos lugares no se lleva a cabo una inspección adecuada, particularmente cuando esta tarea queda a cargo de personas. Sin embargo, la detección automática de objetos a través de sistemas de visión por computadora con cámaras de bajo costo y algoritmos de inteligencia artificial, como el método de la bolsa de palabras visuales (BoVW) son una opción adecuada para inspeccionar en el puesto de control de acceso que los trabajadores y visitantes ocasionales usen cascos de seguridad antes de ingresar a zonas peligrosas. En este artículo reportamos que la etapa de entrenamiento se realizó con imágenes experimentales divididas en dos clases, obtenidas después de aplicar un filtro de detección de bordes y una reducción previa de su tamaño original. Como resultado, se redujo el tiempo promedio de la etapa de entrenamiento a 11.9 segundos y se logró una métrica de exactitud del 95.8%. La etapa de prueba se realizó con imágenes descargadas de internet, y se logró una exactitud del 88.3% en un tiempo promedio de 0.63 segundos. Esto muestra que el método de la bolsa de palabras visuales tiene un buen rendimiento en velocidad y precisión para la tarea de detección del casco de seguridad.
THE RELATIONSHIP OF CORROSION RESISTANCE OF PART SURFACE WITH ADHESIVE STRENGTH OF VIBRATIONAL MECHANCHEMICAL COATINGS
Authors: Lebedev Valeriy , Shtyn' Sergey , Kukarkin Il'ya
Published: November 2023

The paper shows the relationship of corrosion resistance with the strength of mechanochemical zinc coatings formed in vibration technological systems. It is considered that coating process is a combination of mechanical and physico-chemical phenomena occurring simultaneously in the surface layer of the metal under the shock and pulse action of the activating medium indentors on it under conditions of low-frequency oscillations; at the same time, a coating is formed in the zone of local coating-substrate contact interaction, and its main parameter is adhesion. It is found out that the same adhesive strength of the coating can be provided as a result of varying the energy contribution to the process of coating formation by the chemical interaction of the coating medium with metal and the mechanical action of the indentors on the surface to be coated. The correlation dependence of the corrosion resistance estimated by the permeability indicator on the adhesive strength of the coating is proposed, which allows at the stage of technological preparation of production to design technological regulations with sufficient accuracy for practice by regulating the mechanical and chemical parameters of the process, while providing the adhesive strength required by the operating conditions and the most environmentally preferable conditions for the coating. It is noted: the technological efficiency of the coating process with the control of mechanical parameters is 2-3% higher compared to the control of the process by chemical parameters; for structural steel samples, under the selected coating conditions, corrosion resistance increases from 9.8 to 46.6 times in relation to uncoated samples. This indicates a high level of protective anticorrosive properties of vibrational mechanochemical zinc coatings.
PERFIL DE PACIENTES COM ÚLCERAS VENOSAS SUBMETIDOS À TELENFERMAGEM EM UMA CLÍNICA DE ESTOMATERAPIA
Authors: Costa dos Santos Jakeline , Britto Ribeiro de Jesus Patricia , Queiroz dos Anjos Laura , Fernandes Jorge Thamires , Carneiro Carvalho Eloá , Silva de Andrade Karla Biancha , Da Costa Carolina Cabral Pereira , Dantas de Oliveira Souza Norma Valéria
Published: November 2023

Objetivo: descrever o perfil sociodemográfico e clínico de pessoas com úlceras venosas submetidas à Telenfermagem em uma clínica de enfermagem em Estomaterapia. Métodos: estudo documental, descritivo e transversal, com abordagem quantitativa, realizado com 159 prontuários de pacientes com úlceras venosas, acompanhadas por Telenfermagem na Clínica de Enfermagem em Estomaterapia de uma universidade pública do município do Rio de Janeiro, entre os meses de abril de 2018 a fevereiro de 2020. Os dados foram processados pela análise das variáveis por meio de estatística simplificada, auxiliada por uma planilha do aplicativo Microsoft Excel®. Resultados: Apontam uma igualdade entre o sexo biológico dos participantes, composto por 50,94% mulheres e 49,06% homens; na faixa de 60 a 69 anos (32,71%). Constatou-se que 32,07% faziam acompanhamento médico regular na clínica da família; 40,88% possuíam o membro inferior esquerdo acometido por úlcera venosa, sendo a região do maléolo medial mais acometida (38,19%). Outro resultado foi que em 54,72% dos prontuários analisados não houve cicatrização. As úlceras possuíam exsudato com aspecto seroso (71,07%); presença de edema em 79,25%; possuíam lesões que interferiram na deambulação (33,62%); e 35,42% queixavam-se de dor. Conclusão: O perfil apreendido vem ao encontro de outros estudos em relação à maioria das variáveis investigadas e permite planejar um cuidado individualizado e focado nas características apreendidas.
Strategi Pengembangan dan Tata Kelola Manajemen Usaha Mandiri “Bakso Wilujeng” di Kelurahan Ketawanggede - Kota Malang
Authors: Widyastuti Fikka Kartika , Anggraini Sinar Perbawani Abrina , Fitri Ayu Chandra Kartika , Mediaswanti Kun Aussieanita
Published: November 2023

Bakso adalah salah satu usaha kuliner khas Malang yang banyak diminati oleh konsumen dan mempunyai potensi banyak pembeli. Akan tetapi pemilik mengalami masalah dalam produksi bakso karena masih menggunakan cara cetak manual menggunakan tangan. Oleh karena itu, tujuan kegiatan PkM ini adalah membantu mengembangkan produksi usaha UMKM bakso dengan memperbaiki kualitas proses produksi, manajemen keuangan dan pemasaran yang diharapkan dapat meningkatkan daya jangkau pemasaran mitra yang lebih luas, sehingga pendapatan mitra akan bertambah. Metode yang dilakukan adalah melakukan observasi untuk mengetahui permasalah mitra, menyusun tahapan dan teknik penyelesaian masalah, pelaksanaan dan evaluasi kegiatan. Setelah melakukan rangkaian kegiatan pengabdian masyarakat, mitra mendapatkan bantuan alat pencetak bakso, proses pencetakan adonan bakso lebih cepat 35 menit dari sebelumnya, dapat mengelola keuangan dengan memanfaatkan aplikasi keuangan, memahami pentingnya hygiene sanitasi produk makanan, serta meningkatkan promosi di media sosial. Berdasarkan hasil kegiatan pengabdian kepada masyarakat ini mitra menjadi lebih terbantu dengan adanya alat pencetak bakso karena lebih efisien waktu dan lebih higienis, serta dapat membuat laporan keuangan usaha secara otomatis menggunakan aplikasi keuangan.
Control of PD1 by NOD2.
Authors: Mamoor Shahan
Published: November 2023

We provide evidence here from loss-of-function studies in mice and gain-of-function studies in human cells (1, 2) which demonstrate control of PD1, encoded by PDCD1, by the NLR (nucleotide-binding oligomerization domain-like receptor) family protein NOD2. In a heterologous system, human cells expressing Crohn’s Disease mutant NOD2 L1007sfsinsC display compromised ability to induce PD-1 expression.
The Necessary Existence and Death of Organisms to Sustain the Eternity of DNAs
Authors: Orquiza João Carlos
Published: November 2023

This essay introduces the concept of "Dynamic Genostability," a hypothesis that redefines life on Earth as the manifestation of DNA's quest for perpetuation. Contrary to the traditional organism-centric view of evolution, we propose that organisms are merely transient vehicles for DNA, which seeks to maintain its low-entropy state amidst environmental challenges. Through a synthesis of literature on molecular biology, thermodynamics, and evolutionary theory, we explore the role of entropy in DNA stability and the universality of nucleotide bases, challenging the anthropocentric bias in biology. We argue that the diversity of life is a direct consequence of DNA's strategy to ensure its replication, suggesting a shift in conservation ethics and providing new insights for astrobiology. The essay culminates in a call for future research to further explore the implications of this hypothesis, particularly through experimental and observational studies on DNA's resilience to entropy.
Control of PPARG by NOD2.
Authors: Mamoor Shahan
Published: November 2023

We provide evidence here from overexpression-based gain-of-function studies in human cells (1, 2) which demonstrate control of peroxisome proliferator-activated receptor gamma, PPARG, by the NLR (nucleotide-binding oligomerization domain-like receptor) family protein NOD2.
Measuring and Controlling Assets Employed
Authors: Juliawati Nunung
Published: November 2023

Resume ini berisikan penjelasan mengenai Tujuan pengukuran aset yang dimanfaatkan, Mengukur aset yang dimanfaatkan, Mengukur kas, Mengukur piutang dagang, Mengukur sediaan barang dagang, Mengukur aset sewa-guna, Mengukur aset menganggur, Mengukur aset tidak berwujud, Mengukur utang tidak lancar.
Transcranial Histotripsy Applica4on to Cadaveric Brain
Authors: Xu Zhen
Published: November 2023

The goal of this project is to determine whether histotripsy can be used to create lesions at varying locations and volumes within the human brain. The neuronavigation-guided transcranial histotripsy (NaviTH) system with a hemispherical 15-cm radius, 360-element, 700kHz histotripsy array was used. This NaviTH system uses pre-treatment CT and MRI for co-registration with the histotripsy array position to guide the targeting. During the treatment, our transmit-receive capable histotripsy array provides treatment monitoring via cavitation mapping, at on-target and off-target locations as well as locations near or on the skull surface. Histotripsy treatment was applied to the brain of 6 full human cadavers, including 3 unembalmed cadavers within 96-hours post-mortem and 3 embalmed cadavers. Effective ablations were generated in 2 unembalmed cadavers and 1 embalmed cadaver. For the 1 unsuccessful unembalmed cadaver, histotripsy treatment was not effective because of the technical issues with the neuronavigation system. In the 2 unsuccessful embalmed cadavers, histotripsy treatment was not effective due to the cadaver brain being overly gassy, which negatively impacted the histotripsy treatment. The cadavers get gassy quickly post-mortem. In the 3 successful human cadavers, the lesions were created mostly in the central regions, not near the skull surface due to the high attenuation and prefocal pressure hotspot, high tissue gassiness, and experimental timing / duration limitations associated with the university morgue. In addition, we performed simulations showing that the attenuation and prefocal pressure hotspot increases as the target location is closer to the skull surface. Our current 360-element array can treat a wide range of locations within excised human skulls with a high SDR (low density variation over the skull).
Comprehending Turkish Sentences using Word Order, Thematic Roles, and Case
Authors: Ergin Mehmet Yarkın , Stromswold Karin
Published: November 2023

A core aspect of sentence comprehension is assigning thematic roles such as agents and patients to nouns. Turkish, a flexible word order language with accusative case-marking, allows us to compare the relative effect of word order, case-marking, and thematic reversibility in sentence comprehension. We conducted two spoken language comprehension experiments to investigate the relationships among these factors. Native Turkish-speaking adults were faster and more accurate in comprehending sentences with default word order than those with scrambled word order; case-marked sentences than non-casemarked sentences; and sentences with thematically irreversible nouns than those with reversible nouns. The effect of word order depended on the reversibility of the nouns, and case-marking had little-to-no effect on comprehension when the nouns were thematically irreversible. Our results suggest that while Turkish speakers use multiple cues to map thematic roles onto nouns, there are diminishing returns of facilitation with each additional source of information. These results give support to race-based models of sentence comprehension.
Moral judgment is sensitive to bargaining power
Authors: Le Pargneux Arthur , Cushman Fiery Andrews
Published: November 2023

For contractualist accounts of morality, actions are moral if they correspond to what rational or reasonable agents would agree to do, were they to negotiate explicitly. This, in turn, often depends on each party’s bargaining power, which varies with each party’s stakes in the potential agreement and available alternatives in case of disagreement. If there is an asymmetry, with one party enjoying higher bargaining power than another, this party can usually get a better deal, as often happens in real negotiations. A strong test of contractualist accounts of morality, then, is whether moral judgments do take bargaining power into account. We explore this in five preregistered experiments (n = 3,025; US-based Prolific participants). We construct scenarios depicting everyday social interactions between two parties in which one of them can perform a mutually beneficial but unpleasant action. We find that the same actions (asking the other to perform the unpleasant action, or explicitly refusing to do it) are perceived as less morally appropriate when performed by the party with lower bargaining power, as compared to the party with higher bargaining power. In other words, participants tend to give more moral leeway to parties with better bargaining positions, and to hold disadvantaged parties to stricter moral standards. This effect appears to depend only on the relative bargaining power of each party, but not on the magnitude of the bargaining power asymmetry between them. We discuss implications for contractualist theories of moral cognition and the emergence and persistence of unfair norms and inequality.
Sustainability in food-based dietary guidelines: a review of recommendations around meat and dairy consumption and their visual representation
Authors: Sinclair Maddie , Combet Emilie , Davis Tess , Papies Esther K.
Published: November 2023

The transition away from meat and dairy consumption and towards more plant-based diets is vital for meeting environmental sustainability targets, including reducing greenhouse gas (GHG) emissions and land use from food. Food-based dietary guidelines (FBDG) exist to communicate nutrition information to the public of a country’s population. However, it is not known how different countries’ FBDG communicate reducing meat and dairy intake in the context of sustainability. To address this gap, we reviewed global consumer-facing FBDG (n=58) to explore whether and how recommendations and information around meat and dairy consumption were included, and the pictorial representation of these two groups compared to other foods. Few countries used a sustainability argument to recommend reducing meat (6/58) or dairy consumption (2/58). The proportion of dairy images within food guides was consistently higher than meat images. Some countries’ guidelines are starting to consider meat in the context of sustainability and implementing meat reduction as recommendations. However, this is not the case for dairy, potentially due to complex nutritional implications. Overall, our review shows that not enough countries recommend reducing either meat or dairy consumption. Clearer guidelines backed by current evidence are needed, which provide justification behind recommendations, actionable advice for how to meet the recommendations, and appropriate quantified targets or limits of certain foods. This well-rounded advice is imperative to empower citizens to take action on their dietary habits, to reduce global meat and dairy consumption and replace these with more sustainable alternatives for human and planetary health.
Parental attitudes toward sexual orientation and gender diversity: Challenging LGBT discrimination in Australian schools
Authors: Hendriks Jacqueline , Francis Neil , Saltis Hanna , Marson Katrina , Walsh Jenny , Lawton Tasha , Burns Sharyn
Published: November 2023

As the Australian government considers legislative reform regarding the rights of religious schools to discriminate against LGBT students or staff, claims are often made that religious parents or those who enrol their child in religious schools do not affirm diversity of sexuality or gender. Using a national dataset of parents (n=2,418), attitudes toward sexual orientation, gender diversity, homophobia and transphobia were examined. Across all religiosities, school sectors and attitudinal statements, significant majorities reported supportive attitudes (62.7–93.5%). Only small minorities expressly reported negative attitudes (1.6–20.2%). Pairwise religiosity comparisons between parents with children only at a secular school, versus any religious school, revealed few differences. Amongst Catholic parents, those with children at Catholic schools and those with children only at secular schools, held similar attitudes and a majority held favourable attitudes towards sexual and gender diversity, suggesting most Catholic parents who enrol their children in Catholic schools do so despite Catholic doctrine. Findings suggest a significant majority of parents affiliated with religious schools hold supportive attitudes towards diverse sexual orientations, gender diversity, and support actions to address homophobia and transphobia. This empirical evidence contradicts religious schools' calls for rights to discriminate against LGBT persons on the basis of parental attitudes.
Comment on “The real facts supporting Jeanne Calment as the oldest ever human”
Authors: Gibbs Philip , Zak Nikolay
Published: November 2023

In 1997 Jeanne Calment died at a claimed age of 122 years and 164 days. The authenticity of her age was validated by Michel Allard and Jean-Marie Robine who published popular books about her case. In 2018 Nikolay Zak presented evidence that Jeanne Calment’s daughter Yvonne had assumed her mother’s identity. In 2019 the original validators and their colleagues defended their work and tried to refute the points of evidence made by Zak. In this comment we examine their arguments and find that they do not hold up. We provide new damning evidence in favour of the identity switch hypothesis.
Textiloma intraabdominal incidental reconocido en la sala de Emergencia. Reporte de caso clínico
Authors: Robalino Díaz Anderson Raúl , López Buenaño Anngela Germania , Ruiz Chicaiza Aida Emperatriz , Ordoñez Saetama María Olivia
Published: November 2023

Los textilomas son cuerpos originados a partir del material textil quirúrgico olvidado en la cavidad del paciente, provocando una reacción inflamatoria y fibrosis circundante con el pasar del tiempo. El objetivo de este estudio es caracterizar la sospecha, tras el primer contacto con el paciente en la sala de Emergencia. La metodología utilizada en el reporte y análisis de este caso lleva un enfoque observacional, retrospectivo y cualitativo, apoyado en la revisión actualizada de revistas de alto impacto. En los resultados obtenidos se pudo establecer que el cuadro clínico es variado, sin embargo, el dolor, una masa palpable y la respuesta inflamatoria sistémica junto con el antecedente de cirugía abdominal, permiten incrementar la sospecha y direccionar su diagnóstico.
PENETAPAN HARGA JUAL MAKANAN DI RUMAH MAKAN KAMPUNG BAKAU KOTA KENDARI PERSPEKTIF EKONOMI SYARIAH
Authors: Ariyani Nova , Sari Kiki Novita , Lestari Niken
Published: November 2023

This research aims to describe the mechanism for determining food selling prices at the Kampung Bakau Restaurant, Kendari City and to determine the sharia economic view in determining food selling prices at the Kampung Bakau Restaurant, Kendari City. Data collection techniques in this research are by means of documentation, observation and interviews. This type of research is qualitative research, namely research that produces descriptive data in the form of written or spoken words from people and observed behavior. With the aim of getting more comprehensive, valid, reliable and objective results regarding determining food selling prices from a sharia economic perspective at the Kampung Bakau Restaurant, Kendari City.
PERAN ZAKAT PRODUKTIF DALAM UPAYA PENANGGULANGAN KEMISKINAN DENGAN PENDEKATAN MODEL CIBEST
Authors: Abu Rahma Rafifah , Mongkito Abdul Wahid
Published: November 2023

This study aims to examine the impact of productive Zakat on poverty reduction in Kendari City using the CIBEST model. The research addresses two main questions: (1) What is the distribution model of productive Zakat for poverty alleviation at BAZNAS Kendari City (2) What are the effects on recipients (mustahiq) after receiving productive zakat assistance from BAZNAS Kendari City using the CIBEST model. The research adopts a qualitative, descriptive approach, collecting data through interviews, observation, and documentation. The findings indicate that: (1) The productive zakat distribution model focuses on planning, organizing, and implementation stages, with limited supervision due to human resource constraints. (2) Using the CIBEST Model, changes in mustahiq households were observed before and after receiving productive Zakat. Notably, the number of prosperous households increased from 14 to 22 in Quadrant I, while material poverty decreased from 8 to 6 households in Quadrant II. Spiritual poverty decreased from 8 to 2 households in Quadrant III, and no households fell into the absolute poverty category in Quadrant IV, both before and after receiving productive Zakat.
Investigación de las subjetividades y emociones en los procesos de colectivización del cuidado en la vejez: estudios de caso en México, España y Uruguay
Authors: Enríquez Rosas Rocío
Published: November 2023

Nos encontramos en la Década del envejecimiento saludable (2020–2030), que tiene como propósito central la colaboración de los gobiernos, las organizaciones internacionales, las organizaciones de la sociedad civil, las instituciones de educación y salud, así como las comunidades y las familias, para mejorar las condiciones de vida de las personas mayores (OMS, 2020).
La multimensionalidad de la vejez y sus sentidos en personas mayores institucionalizadas y no institucionalizadas: estudios de caso en México, Uruguay y España
Authors: Enríquez Rosas Rocío , Ramírez García María Martha , Espinosa Martínez Aimeé Viridiana
Published: November 2023

Los significados culturales (Bruner, 1990) sobre la vejez, desde la perspectiva de género, así como de la condición de ser personas mayores, institucionalizadas o no, es central en la presente investigación. El acercamiento a la producción de sentido sobre la vejez desde los propios sujetos, así como desde los otros implicados en las relaciones de cuidado (cuidadores, familiares, directivos), permite conocer las formas contemporáneas en que se negocian los sentidos acerca de la vejez y la emergencia de significados que rompen con formas estereotipadas.
RARE BLOOD DISEASES: GAUCHER DISEASE. CASE DESCRIPTION
Authors:   Novosibirsk State Medical University, Novosibirsk, Russia, Pospelova T.I. , Babaeva T.N. ,   Novosibirsk State Medical University, Novosibirsk, Russia
Published: November 2023

Gaucher disease is the most common form of hereditary enzymopathies included in the group of lysosomal storage diseases. The disease is based on a hereditary deficiency in the activity of the enzyme glucocerebrosidase (also called glucosylceramidase or acid β-glucosidase) which is involved in the degradation of cellular metabolic products. Gaucher disease is a systemic disease characterized by the same type of clinical manifestations (hepatosplenomegaly, cytopenias, lesions of the skeletal system) but an extremely heterogeneous clinical course. In the article, the authors describe their own clinical case of Gaucher disease in a teenage girl. A long past history of he¬terogeneous clinical symptoms, the complexity of differential diagnosis and interpretation of existing deviations within the course of the single systemic process were noted. The high effectiveness of modern enzyme replacement therapy has been demonstrated.
Pemanfaatan Rumput Laut Bagi Masyarakat Kecamatan Pontianak Utara Kota Pontianak
Authors: Vatria Belvi
Published: November 2023

Seaweed is one of the fishery commodities which can be used as a mainstay source of the national fisheries economy. Seaweed has long been known in Indonesia as a food, beverage, vegetable and traditional medicine ingredient. The target area for this community service program (PKM) is North Pontianak District, Pontianak City, which is also one of the tourism destinations for the equatorial monument in Indonesia. The partner group selected in this community service program (PKM) is the people of Batulayang Village, North Pontianak District, who are members of the village PKK group of 20 people divided into 5 small groups. The main objective of this PKM activity is to transfer seaweed utilization science and technology through training and assistance in processing food and beverages made from seaweed. In general, the results of this PKM activity run smoothly and thoroughly. After participating in this PKM activity, the training participants gained new skills about seaweed processing, how to make small-scale business feasibility, and how to market the seaweed products that have been produced. There are ten types of processed seaweed products, namely: seaweed brownies, seaweed pudding, seaweed drinks, seaweed bingke cake, seaweed ointment, seaweed sticks, seaweed crackers, seaweed lunkhead, seaweed jely, and sweets. seaweed. Increasing community skills in the use of seaweed is one of the efforts to support the community's economy and stretch tourism in the North Pontianak District.

Key words: economy, livelihood, processing, empowerment
Pelatihan Penggunaan Aplikasi SPSS untuk Statistik Dasar Penelitian bagi Mahasiswa Se-kota Pontianak
Authors: Suprihartini Lia , Rinaldi Hasymi , Saputra Haris Mirza , Sulaiman Sulaiman , Tandra Rudy , Krisandi Samuel Dendy
Published: November 2023

In general, research methodology is divided into quantitative and qualitative methods where quantitative is usually used in exact science studies such as engineering and business, while qualitative is for social humanities studies such as social politics. So that not all higher education students master these two methodologies. This training is specifically designed to provide an understanding of one of the popular research methods, namely the quantitative method related to the use of the SPSS application, especially for students in Pontianak City. Community Service (PPM) is carried out with the aim of being part of increasing the capacity of students in the city of Pontianak regarding understanding the application of SPSS statistics so that it can be better and beneficial for the smooth running of their studies. This activity was held in collaboration with Statistics Indonesia West Kalimantan on July 23 2022 which was attended by approximately 30 participants. Based on the results of the implementation of the PPM activities, it was concluded that with the training activities on the use of this Statistical Application, from the results of observations and observations, students began to open their minds to later try to use Quantitative data processing methods with this SPSS Statistical application. This picture can be seen from the enthusiasm of the participants in carrying out the activity.
The Prejudice towards Blacks in the 16th and 17th Century America
Authors: Gamsakhurdia Nino
Published: November 2023

Historians believe that societal or implicit racism appeared very early, as a consequence of pre-existing European attitude towards blacks. Economic Necessities in America which called for some sort of controlled labor made Africans slaves. By 1640 it was clear that English Settlers kept Negroes as hereditary slaves for life. When English confronted with Africans, they did not realize that Africans were potentially subjects for a special kind of obedience and subordination which was to arise as adventurous Englishmen sought to possess for themselves and their children one of the most bountifulterritories of the earth. In England the concept of blackness was full with intense meaning. Englishmen found in the idea of blackness a way of expressing some of their ingrained values.
Myth in the Novel Khazarula by Nodar Dumbadze
Authors: BAKURIDZE Mariam
Published: November 2023

Nodar Dumbadze’s novel entitled „Khazarula“presents readers a fascinating story of anapple tree and of a wine pitcher. The story mentioned is full with seemingly unnoticed,yet transparent paradigms and is fit to the simplistic style of narration of the author.The readers of Nodar Dumbadze’s writings know quite well the fact that the writer frequentlyuses mythic models in his novels as well as in stories however, there is alwaysa touch of contemporaneity and especially the notion of humanity is being emphasizedin the human characters.
Foreign Policy-Making Processes in XX-XXI Centuries: Theoretical and Practical Background on the Example of the USA
Authors: BERAIA Eka
Published: November 2023

“Avoid entangling alliances”- these words were formulated by George Washington in1789 and contained a message to the country to respect and regard other nations.Those words shaped United States foreign policy for more than a century.Today, as with all policy making, many people and organizations have a hand in settingUnited States foreign policy, but the President almost always has the primary responsibilityfor shaping it.The article aims to represent the political system of the U.S. and its implications towardforeign-policy making provisions, the key members of the foreign policy team players,the missions and goals of the USA government in foreign-policy decision making process.
Global Challenges of Earth Protection and Philosophic Foundation of Cherokee Indian Religion: the 19th Century American Transcendentalism and Georgian “Gialove” in Poetry
Authors: BAKHTADZE Irina
Published: November 2023

Environmental issues now present a greater challenge for the global society than everand demand better cooperation among nations around the world to save the planet andhumans from inevitable disaster which may be caused by environmental degradation.Air and water pollution, depletion of soil, loss of biodiversity, extinction of many speciesare the result of inhuman and irrational attitudes towards the earth and the gifts of nature.Civilization means more people demanding higher standards of living which hasdirect disastrous impacts on world ecosystems because it stimulates exploitation ofrenewable resources, such as fresh water, forests, and fertile topsoil.This article ecological problems caused by the brutal consumption of natural resourcesand the attempt of international community to protect the earth; also it argues that manyancient civilizations, and among them aboriginal Cherokee people, worshiped universalspirit of nature and tried to maintain balance with nature. Based on the analysis offamous essay Nature by the 19th century American essayist and poet Ralph WaldoEmerson and the short stories by Georgian poet and writer Vazha Pshavela, the articlereveals the authors’ philosophy of nature interpreted as a Universal being.The central idea of the paper is that the most important for mankind is to restore “wholeness”with nature and save it from the flaws and distractions imposed by “civilized society”in the post-industrial era. “Gialove” - is an Earth-affection philosophy, which wasbrilliantly demonstrated in Vazha’s poetry and stories.
Роль биомаркёров в оценке поражения тубулоинтерстициальной ткани почек у больных хроническим гломерулонефритом
Authors: Кraydaschenkо О. V. , Аbramov А. V. , Dolinna М. О.
Published: November 2023

Вивчали характер взаємозв'язку між рівнями NGAL і IL-18 сироватки крові, сечі та клініко-морфологічними параметрами, що відображають ураження тубулоінтерстиціальної тканини (ТІТ) нирок у хворих на хронічний гломерулонефрит (ХГН). Обстежено 81 хворого на ХГН, яких розподілено на дві групи залежно від наявності артеріальної гіпертензії (АГ). Рівні NGAL і IL-18 сироватки крові та сечі визначали імуноферментним методом. Для аналізу ураження ТІТ нирок використовували дані прижиттєвого морфологічного дослідження нирок. У хворих на ХГН з АГ спостерігали більш виражені морфологічні зміни ТІТ нирок, що відповідало вищим показникам NGAL сироватки крові та сечі, IL-18 сироватки крові. Виявлені нами кореляційні зв'язки між маркерами та даними морфологічного дослідження нирок дозволяють використовувати NGAL сироватки крові та сечі, IL-18 сироватки крові для оцінки ураження ТІТ нирок при ХГН. NGAL сироватки крові найточніше відображає наявність інтерстиціального фіброзу (ІФ) і змін тубулярної базальної мембрани; NGAL сечі – дистрофії епітелію канальців. IL-18 сироватки крові є показником дистрофії та некрозу епітелію канальців, ІФ.
Роль остеокальцину в перебігу остеоартрозу та цукрового діабету типу 2
Authors: Zhuravlyova L. V. , Oliinyk M. O.
Published: November 2023

Вивчали вплив остеокальцину на перебіг остеоартрозу (ОА), цукрового діабету типу 2 (ЦД 2) та при їх поєднанні. Встановлені достовірні негативні кореляційні зв’язки між рівнем остеокальцину, показниками вуглеводного обміну та клініко-рентгенологічними змінами у хворих на ОА, ЦД 2 і значне підвищення їх при поєднанні ОА й ЦД 2. Відмічено, що зниження рівня остеокальцину у хворих з поєднаним перебігом ОА та ЦД 2, а також негативний кореляційний зв’язок його з показниками вуглеводного обміну і рентгенологічними змінами, з більш вираженим больовим синдромом при ОА можуть свідчити, що недостатність вироблення остеокальцину призводить до більш тяжких змін в перебігу ОА на фоні ЦД 2.
Порівняльна оцінка ефективності використання 13С-змішаного тригліцеридного та 13С-амілазного дихальних тестів у хворих на хронічний панкреатит після холецистектомії
Authors: Sirchak Ye. S.
Published: November 2023

Наведено результати комплексного обстеження 96 хворих після холецистектомії. Виявлено більш високу чутливість та інформативність 13С-змішаного тригліцеридного дихального тесту порівняно з 13С-амілазним дихальним тестом у хворих після холецистектомії для визначення функціональної недостатності підшлункової залози вже на ранніх стадіях її формування.
Рівень лактатдегідрогенази як маркер порушення функції нирок у новонароджених з асфіксією
Authors: Loboda А. M.
Published: November 2023

Стаття присвячена дослідженню можливості визначення рівня лактатдегідрогенази (ЛДГ) в біологічних рідинах як маркера порушення функції нирок та їх енергетичного забезпечення у новонароджених з асфіксією. Обстежено 200 доношених новонароджених з ознаками ушкодження нирок: 100 дітей, які перенесли тяжку асфіксію, та 100 дітей з помірною асфіксією. Активність ЛДГ визначали кінетичним спектрофотометричним методом. Дослідження активності ЛДГ в сечі протягом раннього неонатального періоду доцільно використовувати як неінвазивний маркер для діагностики порушення функції нирок у новонароджених, які перенесли асфіксію. Показник вмісту ЛДГ в сироватці крові можливо застосовувати як один із ранніх маркерів ураження нирок у немовлят з асфіксією.
L’uso della tradizione. “Sacri Canonis Missae Duplex Expositio” di Odone Cameracensis e Franciscus Titelmans
Authors: Mantyk Tomasz Karol
Published: November 2023

Użytek z tradycji. “Sacri Canonis Missae Duplex Expositio” Odona z Cambrai i Franciszka Titelmansa: szesnastowieczne wykorzystanie średniowiecznego dzieła.   Streszczenie Artykuł jest poświęcony komentarzowi do kanonu Mszy Świętej złożonego z XII wiecznego dzieła Odona, biskupa Cambrai i obszernych dodatków autorstwa Franciszka Titelmansa, XVI wiecznego franciszkanina. Stawia pytanie, dlaczego renesansowy teolog postanowił opublikować średniowieczne dzieło wraz ze swoim komentarzem. Ukazuje, iż działo Odona było jednym z ostatnich komentarzy do Eucharystii inspirowanych myślą patrystyczną. Wskazuje to, iż Titelmans mógł mieć intencję odnowy języka teologii sakramentalnej, atakowanej przez reformatorów, przez powrót do terminologii przed-scholastycznej. Z drugiej strony Titelmans nie unikał sformułowań typowo scholastycznych. Wydaje się, że chciał niejako połączyć elementy scholastyczne z patrystycznymi, aby przekonująco wyłożyć katolicką teologię sakramentu ołtarza.
FOOD AND SUSTAINABILITY IN THE TWENTY-FIRST CENTURY
Authors: Collinson Paul , Young Iain , Antal Lucy , Macbeth Helen
Published: November 2023

Sustainability is one of the great problems facing food production today. Using cross-disciplinary perspectives from international scholars working in social, cultural and biological anthropology, ecology and environmental biology, this volume brings many new perspectives to the problems we face. Its cross-disciplinary framework of chapters with local, regional and continental perspectives provides a global outlook on sustainability issues. These case studies will appeal to those working in public sector agencies, NGOs, consultancies and other bodies focused on food security, human nutrition and environmental sustainability.
Domestic Violence: Comparison between Islamic Law and Domestic Violence Act
Authors: Arief Hanafi
Published: November 2023

The purpose of this study was to determine the comparison between Islamic Law and Domestic Violence Law in handling domestic violence in Indonesia. The type of research used is qualitative research with comparative descriptive method. As the only research design, the ethnographic method is the method in this research with descriptive analysis writing techniques, where ethnography itself provides a tool that allows the research process to take place better. The results of this study are from two sources of law, namely Islamic Law and Domestic Violence Law which can be used as a legal basis to punish and limit the arbitrariness of a husband against his wife and family members. In addition, the two sources of law view the need for formal juridical protection of a person's human rights and freedoms, preventing arbitrary acts of violating other people's laws without clear or justified reasons. The conclusion of this study is that there is a relationship between Islamic Law and the Domestic Violence Law, including 1) The views of Islamic law and positive law view that domestic violence or violence against wives is a despicable and promiscuous behavior; 2) Correlation about the purpose of punishment; 3) In terms of punishment, it can be said that punishment in the form of imprisonment is a form of takfir punishment in Islamic criminal law.