bluuebunny/crossref_metadata_2025 huggingface dataset:
Right Place, Right Time: Preferences of Women with Ovarian Cancer for Delivery of CAM Education
Authors: Ebbert Judith , Donovan Kristine , Lengacher Cecile , Fabri Donna , Reich Richard , Daley Ellen , Thompson Erika , Wenham Robert
Published: September 2015

The purpose of this pilot study was to assess the feasibility of on-site complementary and alternative medicine (CAM) education sessions to maximize quality of life for women with ovarian cancer. The pilot intervention consisted of four weekly sessions, each focusing the techniques and benefits of a particular CAM topic (e.g., nutrition, massage, relaxation). Participants were recruited from the Center for Women’s Oncology at H. Lee Moffitt Cancer Center from 2010 to 2012. Eligible participants had an ovarian cancer diagnosis with a life expectancy of at least 12 months, and were 18 years or older. The Gynecologic Oncology research nurse invited women in the outpatient clinic who matched the eligibility criteria. The research nurse explained the study and provided an informed consent form and return envelope. Because ovarian cancer is not only a rare cancer but, also, most patients seen at Moffitt have recurrent or advanced disease, many women did not have an adequate ECOG score. Many women who consented had rapid changes in health status, with morbidity and mortality outpacing recruitment of the 20 needed to proceed with the four education sessions. Baseline and follow-up surveys were conducted to assess changes in QOL, knowledge, and satisfaction with the intervention. While 27 women consented and 24 women completed the baseline survey, only five women participated in the intervention. The five women who participated were all white, and at time of consenting had a mean age of 60 (SD 9.08) and an average of 102 months (SD 120.65) since diagnosis, and were all on active treatment, except for one. The intervention pilot did not encounter difficulties with regard to recruitment, but suffered problems in achieving an adequate number of women to launch the on-site sessions because of rapidly changing morbidity and significant mortality. The team recognized that a larger-scaled intervention comprised of on-site sessions was impractical and compared attendance rates with a more convenient format currently underway in the Women’s Oncology program at Moffitt. While low participation prevented an intervention analysis of scientific merit, the study data is informative with regard to barriers, facilitators, and alternative methods for sharing useful information to women with advanced ovarian cancer. The comparison strongly suggested that CAM education for women compromised by the disease and treatment associated with ovarian cancer would best be delivered in the convenient-access format that allowed remote access to live and recorded discussions of specific topics.
Breath Figure Method for Construction of Honeycomb Films
Authors: Dou Yingying , Jin Mingliang , Zhou Guofu , Shui Lingling
Published: September 2015

Honeycomb films with various building units, showing potential applications in biological, medical, physicochemical, photoelectric, and many other areas, could be prepared by the breath figure method. The ordered hexagonal structures formed by the breath figure process are related to the building units, solvents, substrates, temperature, humidity, air flow, and other factors. Therefore, by adjusting these factors, the honeycomb structures could be tuned properly. In this review, we summarized the development of the breath figure method of fabricating honeycomb films and the factors of adjusting honeycomb structures. The organic-inorganic hybrid was taken as the example building unit to discuss the preparation, mechanism, properties, and applications of the honeycomb films.
Research on the Piezoelectric Properties of AlN Thin Films for MEMS Applications
Authors: Zhang Meng , Yang Jian , Si Chaowei , Han Guowei , Zhao Yongmei , Ning Jin
Published: September 2015

In this paper, the piezoelectric coefficient d33 of AlN thin films for MEMS applications was studied by the piezoresponse force microscopy (PFM) measurement and finite element method (FEM) simulation. Both the sample without a top electrode and another with a top electrode were measured by PFM to characterize the piezoelectric property effectively. To obtain the numerical solution, an equivalent model of the PFM measurement system was established based on theoretical analysis. The simulation results for two samples revealed the effective measurement value d33-test should be smaller than the intrinsic value d33 due to the clamping effect of the substrate and non-ideal electric field distribution. Their influences to the measurement results were studied systematically. By comparing the experimental results with the simulation results, an experimental model linking the actual piezoelectric coefficient d33 with the measurement results d33-test was given under this testing configuration. A novel and effective approach was presented to eliminate the influences of substrate clamping and non-ideal electric field distribution and extract the actual value d33 of AlN thin films.
Dynamic Modeling and Real-Time Monitoring of Froth Flotation
Authors: Popli Khushaal , Sekhavat Masih , Afacan Artin , Dubljevic Stevan , Liu Qi , Prasad Vinay
Published: September 2015

A dynamic fundamental model was developed linking processes from the microscopic scale to the equipment scale for batch froth flotation. State estimation, fault detection, and disturbance identification were implemented using the extended Kalman filter (EKF), which reconciles real-time measurements with dynamic models. The online measurements for the EKF were obtained through image analysis of froth images that were captured and analyzed using the commercial package VisioFroth (Metsor Minerals). The extracted image features were then correlated to recovery using principal component analysis and partial least squares regression. The performance of real-time state estimation and fault detection was validated using batch flotation of pure galena at various operating conditions. The image features that were strongly representative of recovery were identified, and calibration and validation were performed against off-line measurements of recovery. The EKF successfully captured the dynamics of the process by updating the model states and parameters using the online measurements. Finally, disturbances in the air flow rate and impeller speed were introduced into the system, and the dynamic behavior of the flotation process was successfully tracked and the disturbances were identified using state estimation.
Fluorination Effects on NOS Inhibitory Activity of Pyrazoles Related to Curcumin
Authors: Nieto Carla , Cabildo María , Cornago María , Sanz Dionisia , Claramunt Rosa , Torralba María , Torres María , Elguero José , García José , López Ana , Acuña-Castroviejo Darío
Published: September 2015

A series of new (E)-3(5)-[β-(aryl)-ethenyl]-5(3)-phenyl-1H-pyrazoles bearing fluorine atoms at different positions of the aryl group have been synthesized starting from the corresponding β-diketones. All compounds have been characterized by elemental analysis, DSC as well as NMR (1H, 13C, 19F and 15N) spectroscopy in solution and in solid state. Three structures have been solved by X-ray diffraction analysis, confirming the tautomeric forms detected by solid state NMR. The in vitro study of their inhibitory potency and selectivity on the activity of nNOS and eNOS (calcium-calmodulin dependent) as well as iNOS (calcium-calmodulin independent) isoenzymes is presented. A qualitative structure–activity analysis allowed the establishment of a correlation between the presence/ absence of different substituents with the inhibition data proving that fluorine groups enhance the biological activity. (E)-3(5)-[β-(3-Fluoro-4-hydroxyphenyl)-ethenyl]-5(3)-phenyl-1H-pyrazole (13), is the best inhibitor of iNOS, being also more selective towards the other two isoforms.
Wheat Bran Phenolic Acids: Bioavailability and Stability in Whole Wheat-Based Foods
Authors: Laddomada Barbara , Caretto Sofia , Mita Giovanni
Published: September 2015

Wheat bran is generally considered a byproduct of the flour milling industry, but it is a great source of fibers, minerals, and antioxidants that are important for human health. Phenolic acids are a specific class of wheat bran components that may act as antioxidants to prevent heart disease and to lower the incidence of colon cancer. Moreover, phenolic acids have anti-inflammatory properties that are potentially significant for the promotion of gastrointestinal health. Evidence on the beneficial effects of phenolic acids as well as of other wheat bran components is encouraging the use of wheat bran as an ingredient of functional foods. After an overview of the chemistry, function, and bioavailability of wheat phenolic acids, the discussion will focus on how technologies can allow the formulation of new, functional whole wheat products with enhanced health-promoting value and safety without renouncing the good-tasting standards that are required by consumers. Finally, this review summarizes the latest studies about the stability of phenolic acids in wheat foods fortified by the addition of wheat bran, pearled fractions, or wheat bran extracts.
Antigenotoxicity and Tumor Growing Inhibition by Leafy Brassica carinata and Sinigrin
Authors: Lozano-Baena María-Dolores , Tasset Inmaculada , Obregón-Cano Sara , De Haro-Bailon Antonio , Muñoz-Serrano Andrés , Alonso-Moraga Ángeles
Published: September 2015

Cruciferous vegetables are well known and worldwide consumed due to their health benefits and cancer prevention properties. As a desirable cruciferous plant, Ethiopian mustard (Brassica carinata A. Braun) and its glucosinolate sinigrin were tested in the in vivo Drosophila melanogaster (SMART) and the in vitro HL60 (human promyelocytic leukaemia cell line) systems. High performance liquid chromatography (HPLC) analysis of plant samples confirmed the presence of sinigrin as principal B. carinata glucosinolate. SMART was performed by feeding D. melanogaster larvae either with different concentrations of plant/compound samples or combining them with hydrogen peroxide (a potent oxidative mutagen) being both antimutagenics. HL60 assays showed the tumoricidal activity of plant samples (IC50 = 0.28 mg·mL−1) and the breakdown products of sinigrin hydrolysis (IC50 = 2.71 µM). Our results enhance the potential of B. carinata as health promoter and chemopreventive in both systems and the leading role of sinigrin in these effects.
p38α MAPK and Type I Inhibitors: Binding Site Analysis and Use of Target Ensembles in Virtual Screening
Authors: Astolfi Andrea , Iraci Nunzio , Sabatini Stefano , Barreca Maria , Cecchetti Violetta
Published: September 2015

Mitogen-activated protein kinase p38α plays an essential role in the regulation of pro-inflammatory signaling, and selective blockade of this kinase could be efficacious in many pathological processes. Despite considerable research efforts focused on the discovery and development of p38α MAPK inhibitors, no drug targeting this protein has been approved for clinical use so far. We herein analyze the available crystal structures of p38α MAPK in complex with ATP competitive type I inhibitors, getting insights into ATP binding site conformation and its influence on automated molecular docking results. The use of target ensembles, rather than single conformations, resulted in a performance improvement in both the ability to reproduce experimental bound conformations and the capability of mining active molecules from compound libraries. The information gathered from this study can be exploited in structure-based drug discovery programs having as the ultimate aim the identification of novel p38α MAPK type I inhibitors.
Synthesis of Mesoporous Metal Oxides by Structure Replication: Thermal Analysis of Metal Nitrates in Porous Carbon Matrices
Authors: Weinberger Christian , Roggenbuck Jan , Hanss Jan , Tiemann Michael
Published: September 2015

A variety of metal nitrates were filled into the pores of an ordered mesoporous CMK-3 carbon matrix by solution-based impregnation. Thermal conversion of the metal nitrates into the respective metal oxides, and subsequent removal of the carbon matrix by thermal combustion, provides a versatile means to prepare mesoporous metal oxides (so-called nanocasting). This study aims to monitor the thermally induced processes by thermogravimetric analysis (TGA), coupled with mass ion detection (MS). The highly dispersed metal nitrates in the pores of the carbon matrix tend to react to the respective metal oxides at lower temperature than reported in the literature for pure, i.e., carbon-free, metal nitrates. The subsequent thermal combustion of the CMK-3 carbon matrix also occurs at lower temperature, which is explained by a catalytic effect of the metal oxides present in the pores. This catalytic effect is particularly strong for oxides of redox active metals, such as transition group VII and VIII metals (Mn, Fe, Co, Ni), Cu, and Ce.
Patterns of Sweet Taste Liking: A Pilot Study
Authors: Asao Keiko , Miller Jason , Arcori Leann , Lumeng Julie , Han-Markey Theresa , Herman William
Published: September 2015

Two distinct patterns of sweet taste liking have been described: one showing a peak liking response in the mid-range of sucrose concentrations and the other showing a monotonic liking response at progressively higher sucrose concentrations. Classification of these patterns has been somewhat arbitrary. In this report, we analyzed patterns of sweet taste liking in a pilot study with 26 adults including 14 women and 12 men, 32.6 ± 14.5 years of age with body mass index 26.4 ± 5.1 kg/m2 (mean ± SD). Sweet taste liking was measured for 10 levels of sucrose solutions (0.035 M to 1.346 M). Participants rated their liking of each solution using a visual analog scale with 0 indicating strongly disliking and 100 strongly liking. The cluster analysis demonstrated two distinct groups: 13 liked relatively low sucrose concentrations and liked high sucrose concentrations less, and 13 liked high sucrose concentrations greatly. If we use the 0.598 M sucrose solution alone and a cutoff liking score of 50, we can distinguish the two clusters with high sensitivity (100%) and specificity (100%). If validated in additional studies, this simple tool may help us to better understand eating behaviors and the impact of sweet taste liking on nutrition-related disorders.
High Fat Diet Exposure during Fetal Life Enhances Plasma and Hepatic Omega-6 Fatty Acid Profiles in Fetal Wistar Rats
Authors: Cerf Marlon , Louw Johan , Herrera Emilio
Published: September 2015

Pregnant rats were fed a high fat diet (HFD) for the first (HF1), second (HF2), third (HF3) or all three weeks (HFG) of gestation. Maintenance on a HFD during specific periods of gestation was hypothesized to alter fetal glycemia, insulinemia, induce insulin resistance; and alter fetal plasma and hepatic fatty acid (FA) profiles. At day 20 of gestation, fetal plasma and hepatic FA profiles were determined by gas chromatography; body weight, fasting glycemia, insulinemia and the Homeostasis Model Assessment (HOMA-insulin resistance) were also determined. HF3 fetuses were heaviest concomitant with elevated glycemia and insulin resistance (p < 0.05). HFG fetuses had elevated plasma linoleic (18:2 n-6) and arachidonic (20:4 n-6) acid proportions (p < 0.05). In the liver, HF3 fetuses displayed elevated linoleic, eicosatrienoic (20:3 n-6) and arachidonic acid proportions (p < 0.05). HFG fetuses had reduced hepatic docosatrienoic acid (22:5 n-3) proportions (p < 0.05). High fat maintenance during the final week of fetal life enhances hepatic omega-6 FA profiles in fetuses concomitant with hyperglycemia and insulin resistance thereby presenting a metabolically compromised phenotype.
U.S. Pharmacist Opinions Regarding the Rescheduling of Hydrocodone Combination Products: A Pilot Study
Authors: Covvey Jordan , Pfalzgraf Andrea , Cohron Peter
Published: September 2015

In October 2014, the Drug Enforcement Administration in the U.S. reclassified hydrocodone combination products (HCPs) from Schedule III to Schedule II, initiating one of the most significant and controversial regulatory changes for opioids in recent national history. The aim of the present study was to determine community pharmacist opinions on the effect of the rescheduling of HCPs on their personal practice. A web-based pilot survey was emailed to a convenience sample through online newsletters of professional pharmacy organizations in Pennsylvania, Kentucky and West Virginia in April/May 2015. A total of 62 surveys were initiated, yielding 56 complete responses. More than 75% of respondents noted increases in their workload as a result of the rescheduling of HCPs. Opinions regarding the intended outcomes of rescheduling were only weakly positive, with only 37.5% of respondents believing it has increased safety and 44.6% of respondents believing it has lessened abuse/diversion. For overall attitudes regarding the rescheduling, respondents were split between positive (26.8%), neutral (26.8%) and negative (46.4%). These initial data suggest that pharmacists have encountered barriers in practice resulting from the rescheduling. Further expanded work is necessary to verify these results from the small sample, and to assess the intended effects of the rescheduling upon the safe and effective use of hydrocodone.
Rice Phytochrome B (OsPhyB) Negatively Regulates Dark- and Starvation-Induced Leaf Senescence
Authors: Piao Weilan , Kim Eun-Young , Han Su-Hyun , Sakuraba Yasuhito , Paek Nam-Chon
Published: September 2015

Light regulates leaf senescence and light deprivation causes large-scale transcriptional reprogramming to dismantle cellular components and remobilize nutrients to sink organs, such as seeds and storage tissue. We recently reported that in Arabidopsis (Arabidopsis thaliana), Phytochrome-Interacting Factor4 (PIF4) and PIF5 promote dark-induced senescence and natural senescence by directly activating the expression of typical senescence-associated genes (SAGs), including ORESARA1 (ORE1) and ETHYLENE INSENSITIVE3 (EIN3). In contrast, phytochrome B (PhyB) inhibits leaf senescence by repressing PIF4 and PIF5 at the post-translational level. Although we found how red light signaling represses leaf senescence in Arabidopsis, it remains unknown whether PhyB and/or PhyA are involved in leaf senescence in rice (Oryza sativa). Here we show that rice phyB knockout mutants (osphyB-1, -2, and -3) exhibited an early senescence phenotype during dark-induced senescence, but an osphyA knockout mutant (osphyA-3) senesced normally. The RT-qPCR analysis revealed that several senescence-associated genes, including OsORE1 and OsEIN3, were significantly up-regulated in osphyB-2 mutants, indicating that OsPhyB also inhibits leaf senescence, like Arabidopsis PhyB. We also found that leaf segments of osphyB-2 senesced faster even under light conditions. Supplementation with nitrogen compounds, such as KNO3 and NH4NO3, rescued the early senescence phenotype of osphyB-2, indicating that starvation is one of the major signaling factors in the OsPhyB-dependent leaf senescence pathway.
The Influence of Diesel Fuel Subsidies and Taxes on the Potential for Solar-Powered Hybrid Systems in Africa
Authors: Bertheau Paul , Cader Catherina , Huyskens Hendrik , Blechinger Philipp
Published: September 2015

Many people in African countries lack access to sufficient electricity supply due to missing infrastructure of the centralized conventional power generation system. In order to provide electricity to a wider part of the population, it is necessary to exploit the vast renewable resources in African countries. Therefore, this paper scrutinizes the economic advantages of photovoltaic-based hybrid systems over fossil fuel-based power generation. A simulation model is applied in order to calculate the cost advantage of hybrid systems compared to diesel-only systems for the entire continent on a long term basis by applying two scenarios: one based on world market diesel prices and the other one based on national diesel prices. The results indicate that average power generation costs per country can be reduced by up to 0.11 €/kWh considering world market diesel prices and by up to 0.48 €/kWh considering national diesel prices. Furthermore, the effect of diesel fuel subsidies and taxes on the renewable energy potential and the respective savings are examined. These findings may ameliorate the policy development according to fossil fuel subsidies and taxes and demonstrate the advantages of decentralized renewable hybrid systems especially in rural areas of Africa.
A Spatial Queuing-Based Algorithm for Multi-Robot Task Allocation
Authors: Lenagh William , Dasgupta Prithviraj , Munoz-Melendez Angelica
Published: September 2015

Multi-robot task allocation (MRTA) is an important area of research in autonomous multi-robot systems. The main problem in MRTA is to allocate a set of tasks to a set of robots so that the tasks can be completed by the robots while ensuring that a certain metric, such as the time required to complete all tasks, or the distance traveled, or the energy expended by the robots is reduced. We consider a scenario where tasks can appear dynamically and a task needs to be performed by multiple robots to be completed. We propose a new algorithm called SQ-MRTA (Spatial Queueing-MRTA) that uses a spatial queue-based model to allocate tasks between robots in a distributed manner. We have implemented the SQ-MRTA algorithm on accurately simulated models of Corobot robots within the Webots simulator for different numbers of robots and tasks and compared its performance with other state-of-the-art MRTA algorithms. Our results show that the SQ-MRTA algorithm is able to scale up with the number of tasks and robots in the environment, and it either outperforms or performs comparably with respect to other distributed MRTA algorithms.
Time-domain Statistics of the Electromagnetic Bias in GNSS-Reflectometry
Authors: Ghavidel Ali , Camps Adriano
Published: September 2015

Global Navigation Satellite Systems-Reflectometry (GNSS-R) is an emerging remote sensing technique that uses navigation signals reflected on the Earth’s surface as sources of opportunity for scatterometry and altimetry. The time-domain statistics of the electromagnetic bias in GNSS-R altimetry are investigated to assess the residual electromagnetic bias after averaging during the dwell time (as long as 100 s). A three-dimensional time-evolving sea surface is generated using Elfouhaily’s ocean surface height spectrum and spreading function. This surface is illuminated by a right hand circular polarization electromagnetic wave at L-band. Then, the scattered waves are computed using the Physical Optics method under the Kirchhoff Approximation. The electromagnetic bias is estimated using a numerical technique previously validated at C- and Ku-bands, and then extrapolated at L-band. Montecarlo simulations for different sea surface realizations consecutive in time are performed so as to analyze the electromagnetic bias statistics up to the 4PthP order moments. Histograms and distribution of the time domain electromagnetic bias are also used for statistical interpretation. All statistical descriptors confirmed that the electromagnetic bias has a non-Gaussian behavior. This study is important to assess the residual electromagnetic bias in future GNSS-R altimetry missions, such as the “GNSS Reflectometry, Radio Occultation and Scatterometry on board the International Space Station” experiment onboard the International Space Station.
The EnMAP-Box—A Toolbox and Application Programming Interface for EnMAP Data Processing
Authors: Van der Linden Sebastian , Rabe Andreas , Held Matthias , Jakimow Benjamin , Leitão Pedro , Okujeni Akpona , Schwieder Marcel , Suess Stefan , Hostert Patrick
Published: September 2015

The EnMAP-Box is a toolbox that is developed for the processing and analysis of data acquired by the German spaceborne imaging spectrometer EnMAP (Environmental Mapping and Analysis Program). It is developed with two aims in mind in order to guarantee full usage of future EnMAP data, i.e., (1) extending the EnMAP user community and (2) providing access to recent approaches for imaging spectroscopy data processing. The software is freely available and offers a range of tools and applications for the processing of spectral imagery, including classical processing tools for imaging spectroscopy data as well as powerful machine learning approaches or interfaces for the integration of methods available in scripting languages. A special developer version includes the full open source code, an application programming interface and an application wizard for easy integration and documentation of new developments. This paper gives an overview of the EnMAP-Box for users and developers, explains typical workflows along an application example and exemplifies the concept for making it a frequently used and constantly extended platform for imaging spectroscopy applications.
Stochastic Resonance in an Underdamped System with Pinning Potential for Weak Signal Detection
Authors: Zhang Haibin , He Qingbo , Kong Fanrang
Published: September 2015

Stochastic resonance (SR) has been proved to be an effective approach for weak sensor signal detection. This study presents a new weak signal detection method based on a SR in an underdamped system, which consists of a pinning potential model. The model was firstly discovered from magnetic domain wall (DW) in ferromagnetic strips. We analyze the principle of the proposed underdamped pinning SR (UPSR) system, the detailed numerical simulation and system performance. We also propose the strategy of selecting the proper damping factor and other system parameters to match a weak signal, input noise and to generate the highest output signal-to-noise ratio (SNR). Finally, we have verified its effectiveness with both simulated and experimental input signals. Results indicate that the UPSR performs better in weak signal detection than the conventional SR (CSR) with merits of higher output SNR, better anti-noise and frequency response capability. Besides, the system can be designed accurately and efficiently owing to the sensibility of parameters and potential diversity. The features also weaken the limitation of small parameters on SR system.
Efficient, Decentralized Detection of Qualitative Spatial Events in a Dynamic Scalar Field
Authors: Jeong Myeong-Hun , Duckham Matt
Published: September 2015

This paper describes an efficient, decentralized algorithm to monitor qualitative spatial events in a dynamic scalar field. The events of interest involve changes to the critical points (i.e., peak, pits and passes) and edges of the surface network derived from the field. Four fundamental types of event (appearance, disappearance, movement and switch) are defined. Our algorithm is designed to rely purely on qualitative information about the neighborhoods of nodes in the sensor network and does not require information about nodes’ coordinate positions. Experimental investigations confirm that our algorithm is efficient, with O(n) overall communication complexity (where n is the number of nodes in the sensor network), an even load balance and low operational latency. The accuracy of event detection is comparable to established centralized algorithms for the identification of critical points of a surface network. Our algorithm is relevant to a broad range of environmental monitoring applications of sensor networks.
Received Signal Strength Database Interpolation by Kriging for a Wi-Fi Indoor Positioning System
Authors: Jan Shau-Shiun , Yeh Shuo-Ju , Liu Ya-Wen
Published: September 2015

The main approach for a Wi-Fi indoor positioning system is based on the received signal strength (RSS) measurements, and the fingerprinting method is utilized to determine the user position by matching the RSS values with the pre-surveyed RSS database. To build a RSS fingerprint database is essential for an RSS based indoor positioning system, and building such a RSS fingerprint database requires lots of time and effort. As the range of the indoor environment becomes larger, labor is increased. To provide better indoor positioning services and to reduce the labor required for the establishment of the positioning system at the same time, an indoor positioning system with an appropriate spatial interpolation method is needed. In addition, the advantage of the RSS approach is that the signal strength decays as the transmission distance increases, and this signal propagation characteristic is applied to an interpolated database with the Kriging algorithm in this paper. Using the distribution of reference points (RPs) at measured points, the signal propagation model of the Wi-Fi access point (AP) in the building can be built and expressed as a function. The function, as the spatial structure of the environment, can create the RSS database quickly in different indoor environments. Thus, in this paper, a Wi-Fi indoor positioning system based on the Kriging fingerprinting method is developed. As shown in the experiment results, with a 72.2% probability, the error of the extended RSS database with Kriging is less than 3 dBm compared to the surveyed RSS database. Importantly, the positioning error of the developed Wi-Fi indoor positioning system with Kriging is reduced by 17.9% in average than that without Kriging.
Illumination and Reflectance Estimation with its Application in Foreground Detection
Authors: Tu Gang , Karstoft Henrik , Pedersen Lene , Jørgensen Erik
Published: September 2015

In this paper, we introduce a novel approach to estimate the illumination and reflectance of an image. The approach is based on illumination-reflectance model and wavelet theory. We use a homomorphic wavelet filter (HWF) and define a wavelet quotient image (WQI) model based on dyadic wavelet transform. The illumination and reflectance components are estimated by using HWF and WQI, respectively. Based on the illumination and reflectance estimation we develop an algorithm to segment sows in grayscale video recordings which are captured in complex farrowing pens. Experimental results demonstrate that the algorithm can be applied to detect the domestic animals in complex environments such as light changes, motionless foreground objects and dynamic background.
Adaptive Correlation Space Adjusted Open-Loop Tracking Approach for Vehicle Positioning with Global Navigation Satellite System in Urban Areas
Authors: Ruan Hang , Li Jian , Zhang Lei , Long Teng
Published: September 2015

For vehicle positioning with Global Navigation Satellite System (GNSS) in urban areas, open-loop tracking shows better performance because of its high sensitivity and superior robustness against multipath. However, no previous study has focused on the effects of the code search grid size on the code phase measurement accuracy of open-loop tracking. Traditional open-loop tracking methods are performed by the batch correlators with fixed correlation space. The code search grid size, which is the correlation space, is a constant empirical value and the code phase measuring accuracy will be largely degraded due to the improper grid size, especially when the signal carrier-to-noise density ratio (C/N0) varies. In this study, the Adaptive Correlation Space Adjusted Open-Loop Tracking Approach (ACSA-OLTA) is proposed to improve the code phase measurement dependent pseudo range accuracy. In ACSA-OLTA, the correlation space is adjusted according to the signal C/N0. The novel Equivalent Weighted Pseudo Range Error (EWPRE) is raised to obtain the optimal code search grid sizes for different C/N0. The code phase measuring errors of different measurement calculation methods are analyzed for the first time. The measurement calculation strategy of ACSA-OLTA is derived from the analysis to further improve the accuracy but reduce the correlator consumption. Performance simulation and real tests confirm that the pseudo range and positioning accuracy of ASCA-OLTA are better than the traditional open-loop tracking methods in the usual scenarios of urban area.
GNSS Signal Tracking Performance Improvement for Highly Dynamic Receivers by Gyroscopic Mounting Crystal Oscillator
Authors: Abedi Maryam , Jin Tian , Sun Kewen
Published: September 2015

In this paper, the efficiency of the gyroscopic mounting method is studied for a highly dynamic GNSS receiver’s reference oscillator for reducing signal loss. Analyses are performed separately in two phases, atmospheric and upper atmospheric flights. Results show that the proposed mounting reduces signal loss, especially in parts of the trajectory where its probability is the highest. This reduction effect appears especially for crystal oscillators with a low elevation angle g-sensitivity vector. The gyroscopic mounting influences frequency deviation or jitter caused by dynamic loads on replica carrier and affects the frequency locked loop (FLL) as the dominant tracking loop in highly dynamic GNSS receivers. In terms of steady-state load, the proposed mounting mostly reduces the frequency deviation below the one-sigma threshold of FLL (1σFLL). The mounting method can also reduce the frequency jitter caused by sinusoidal vibrations and reduces the probability of signal loss in parts of the trajectory where the other error sources accompany this vibration load. In the case of random vibration, which is the main disturbance source of FLL, gyroscopic mounting is even able to suppress the disturbances greater than the three-sigma threshold of FLL (3σFLL). In this way, signal tracking performance can be improved by the gyroscopic mounting method for highly dynamic GNSS receivers.
Structural Stability Monitoring of a Physical Model Test on an Underground Cavern Group during Deep Excavations Using FBG Sensors
Authors: Li Yong , Wang Hanpeng , Zhu Weishen , Li Shucai , Liu Jian
Published: September 2015

Fiber Bragg Grating (FBG) sensors are comprehensively recognized as a structural stability monitoring device for all kinds of geo-materials by either embedding into or bonding onto the structural entities. The physical model in geotechnical engineering, which could accurately simulate the construction processes and the effects on the stability of underground caverns on the basis of satisfying the similarity principles, is an actual physical entity. Using a physical model test of underground caverns in Shuangjiangkou Hydropower Station, FBG sensors were used to determine how to model the small displacements of some key monitoring points in the large-scale physical model during excavation. In the process of building the test specimen, it is most successful to embed FBG sensors in the physical model through making an opening and adding some quick-set silicon. The experimental results show that the FBG sensor has higher measuring accuracy than other conventional sensors like electrical resistance strain gages and extensometers. The experimental results are also in good agreement with the numerical simulation results. In conclusion, FBG sensors could effectively measure small displacements of monitoring points in the whole process of the physical model test. The experimental results reveal the deformation and failure characteristics of the surrounding rock mass and make some guidance for the in situ engineering construction.
Technologies for Assessment of Motor Disorders in Parkinson’s Disease: A Review
Authors: Oung Qi , Muthusamy Hariharan , Lee Hoi , Basah Shafriza , Yaacob Sazali , Sarillee Mohamed , Lee Chia
Published: September 2015

Parkinson’s Disease (PD) is characterized as the commonest neurodegenerative illness that gradually degenerates the central nervous system. The goal of this review is to come out with a summary of the recent progress of numerous forms of sensors and systems that are related to diagnosis of PD in the past decades. The paper reviews the substantial researches on the application of technological tools (objective techniques) in the PD field applying different types of sensors proposed by previous researchers. In addition, this also includes the use of clinical tools (subjective techniques) for PD assessments, for instance, patient self-reports, patient diaries and the international gold standard reference scale, Unified Parkinson Disease Rating Scale (UPDRS). Comparative studies and critical descriptions of these approaches have been highlighted in this paper, giving an insight on the current state of the art. It is followed by explaining the merits of the multiple sensor fusion platform compared to single sensor platform for better monitoring progression of PD, and ends with thoughts about the future direction towards the need of multimodal sensor integration platform for the assessment of PD.
Angle Specific Analysis of Side-to-Side Asymmetry in the Shoulder Rotators
Authors: Ruas Cassio , Pinto Ronei , Cadore Eduardo , Brown Lee
Published: September 2015

Although side-to-side asymmetry of the shoulder rotators calculated by independent peak torque (IPT) has been used for interpretation of injury risks in athletes, it may not measure strength through the entire range of motion (ROM) tested. The aim of this study was to compare side-to-side asymmetry of the shoulder rotators between independent peak torque (IPT) and ten-degree angle specific torque (AST). Twenty healthy adult males (24.65 ± 2.4 years) performed concentric and eccentric internal rotation (IR) and external rotation (ER) of the preferred and non-preferred arms on an isokinetic dynamometer at 60°/s through 150° of total ROM. The total ROM was divided into 14 ten-degree angles of the physiological ROM from −90° of ER to 60° of IR. Concentric and eccentric IR IPT (10.5% ± 8.7% and 12.1% ± 7.2%) and ER IPT (13.6% ± 9.8% and 8.7% ± 5.6%) were significantly less than AST at several angles (p < 0.05). IPT might lead to erroneous interpretations of side-to-side asymmetry in the shoulder rotators and does not represent the entire ROM tested. This information could be used to prescribe strength exercises to enhance overhead performance and reduce risk of shoulder injuries.
Kinematics and Kinetics of Youth Baseball Catchers and Pitchers
Authors: Oliver Gretchen , Lohse Keith , Gascon Sarah
Published: September 2015

The purpose of this study was to compare the throwing kinematics and kinetics of youth catchers and pitchers. It was hypothesized that catchers and pitchers would exhibit differences throughout the throwing motion. Descriptive statistics were used to investigate kinematics during the four events of throwing: foot contact (FC), maximum shoulder external rotation (MER), ball release (BR) and maximum shoulder internal rotation (MIR). Additionally, kinetics were investigated within phases of the events: Phase 1 (cocking; FC to MER), Phase 2 (acceleration; MER to BR) and Phase 3 (deceleration; BR to MIR). Results revealed significant difference in torso flexion, lateral flexion, pelvis lateral flexion and segment velocities between the catchers and pitchers. Based on data from the current study, it appears that the youth catchers execute their throw as they have been instructed. It is unclear if the throwing mechanics displayed by these youth are efficient for a catcher, thus further investigation is needed to determine long-term injury susceptibility.
The Economic Impact of Climate Change on Road Infrastructure in Ghana
Authors: Twerefou Daniel , Chinowsky Paul , Adjei-Mantey Kwame , Strzepek Niko
Published: September 2015

This paper estimates the economic impact of climate change on road infrastructure using the stressor-response methodology. Our analysis indicates that it could cumulatively (2020–2100) cost Ghana $473 million to maintain and repair damages caused to existing roads as a result of climate change (no adapt scenario). However, if the country adapts the design and construction of new road infrastructure, expected to occur over the asset’s lifespan (adapt scenario), the total cumulative cost could increase to $678.47 million due to the initial costs of adaptation. This investment provides lower costs on a decadal basis later in the infrastructure lifespan. This creates the planning question of whether lower decadal costs in the future are a priority or if minimizing initial costs is a priority. The paper addresses this question through decadal and average annual costs up to the year 2100 for the ten regions, using the potential impacts of 54 distinct potential climate scenarios.
Parametric Assessment of Water Use Vulnerability Variations Using SWAT and Fuzzy TOPSIS Coupled with Entropy
Authors: Won Kwangjai , Chung Eun-Sung , Choi Sung-Uk
Published: September 2015

This study assessed the water use vulnerability to include the uncertainty of the weighting values of evaluation criteria and the annual variations of performance values using fuzzy TOPSIS coupled with the Shannon entropy method. This procedure was applied to 12 major basins covering about 88% territory of South Korea. Hydrological components were simulated using Soil and Water Assessment Tool (SWAT) of which parameters were optimally calibrated using SWAT-CUP model. The 15 indicators including hydrological and anthropogenic factors were selected, based on three aspects of climate exposure, sensitivity and adaptive capacity. Their weighting values were objectively quantified using the Entropy method. All performance values of 12 basins obtained from statistic Korea and SWAT simulation were normalized with the consideration of the annual variations from 1991 to 2014 using triangular fuzzy numbers (TFNs). Then, Fuzzy Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) technique was used to quantify the water use vulnerability and rank 12 basins as follows: A12 (Hyeongsan River) > A6 (Seomjin River) > A5 (Youngsan River) > A8 (Mangyung River) > A2 (Ansung River) > A9 (Dongjin River) > A10 (Nakdong River) > A3 (Geum River) > A4 (Sapgyo River) > A11 (Taehwa River) > A7 (Tamjin River) > A1 (Han River). This framework can be used to determine the spatial priority for sustainable water resources plan and applied to derive the climate change vulnerability on sustainable water resources.
Sustainable Water Systems for the City of Tomorrow—A Conceptual Framework
Authors: Ma Xin , Xue Xiaobo , González-Mejía Alejandra , Garland Jay , Cashdollar Jennifer
Published: September 2015

Urban water systems are an example of complex, dynamic human–environment coupled systems which exhibit emergent behaviors that transcend individual scientific disciplines. While previous siloed approaches to water services (i.e., water resources, drinking water, wastewater, and stormwater) have led to great improvements in public health protection, sustainable solutions for a growing global population facing increased resource constraints demand a paradigm shift based on holistic management to maximize the use and recovery of water, energy, nutrients, and materials. The objective of this review paper is to highlight the issues in traditional water systems including water demand and use, centralized configuration, sewer collection systems, characteristics of mixed wastewater, and to explore alternative solutions such as decentralized water systems, fit for purpose and water reuse, natural/green infrastructure, vacuum sewer collection systems, and nutrient/energy recovery. This review also emphasizes a system thinking approach for evaluating alternatives that should include sustainability indicators and metrics such as emergy to assess global system efficiency. An example paradigm shift design for urban water system is presented, not as the recommended solution for all environments, but to emphasize the framework of system-level analysis and the need to visualize water services as an organic whole. When water systems are designed to maximize the resources and optimum efficiency, they are more prevailing and sustainable than siloed management because a system is more than the sum of its parts.
Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain Superfamily
Authors: Nelson Christopher , Epperson Megan , Singh Sukrit , Elliott Jabari , Fremont Daved
Published: September 2015

Poxviruses encode a broad array of proteins that serve to undermine host immune defenses. Structural analysis of four of these seemingly unrelated proteins revealed the recurrent use of a conserved beta-sandwich fold that has not been observed in any eukaryotic or prokaryotic protein. Herein we propose to call this unique structural scaffolding the PIE (Poxvirus Immune Evasion) domain. PIE domain containing proteins are abundant in chordopoxvirinae, with our analysis identifying 20 likely PIE subfamilies among 33 representative genomes spanning 7 genera. For example, cowpox strain Brighton Red appears to encode 10 different PIEs: vCCI, A41, C8, M2, T4 (CPVX203), and the SECRET proteins CrmB, CrmD, SCP-1, SCP-2, and SCP-3. Characterized PIE proteins all appear to be nonessential for virus replication, and all contain signal peptides for targeting to the secretory pathway. The PIE subfamilies differ primarily in the number, size, and location of structural embellishments to the beta-sandwich core that confer unique functional specificities. Reported ligands include chemokines, GM-CSF, IL-2, MHC class I, and glycosaminoglycans. We expect that the list of ligands and receptors engaged by the PIE domain will grow as we come to better understand how this versatile structural architecture can be tailored to manipulate host responses to infection.
Optimized design of a nanostructured SPCE-based multipurpose biosensing platform formed by ferrocene-tethered electrochemically-deposited cauliflower-shaped gold nanoparticles
Authors: Argoubi Wicem , Saadaoui Maroua , Ben Aoun Sami , Raouafi Noureddine
Published: September 2015

The demand for on-site nanodevices is constantly increasing. The technology development for the design of such devices is highly regarded. In this work, we report the design of a disposable platform that is structured with cauliflower-shaped gold nanoparticles (cfAuNPs) and we show its applications in immunosensing and enzyme-based detection. The electrochemical reduction of Au(III) allows for the electrodeposition of highly dispersed cauliflower-shaped gold nanoparticles on the surface of screen-printed carbon electrodes (SPCEs). The nanostructures were functionalized using ferrocenylmethyl lipoic acid ester which allowed for the tethering of the ferrocene group to gold, which serves as an electrochemical transducer/mediator. The bioconjugation of the surface with anti-human IgG antibody (α-hIgG) or horseradish peroxidase (HRP) enzyme yields biosensors, which have been applied for the selective electrochemical detection of human IgG (hIgG) or H2O2 as model analytes, respectively. Parameters such as the number of sweeps, amount of charge generated from the oxidation of the electrodeposited gold, time of incubation and concentration of the ferrocene derivatives have been studied using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and scanning electron microscopy (SEM). Selectivity and specificity tests have been also performed in the presence of potentially interfering substances to either hIgG or H2O2. Results showed that the devised immunosensor is endowed with good selectivity and specificity in the presence of several folds of competitive analytes. The enzyme-based platform showed a good catalytic activity towards H2O2 oxidation which predestined it to potential applications pertaining to enzymatic kinetics studies. The levels of hIgG in human serum and H2O2 in honey were successfully determined and served as assessment tools of the applicability of the platforms for real samples analysis.