bluuebunny/crossref_metadata_2025 huggingface dataset:
Toxina botulínica en la neuralgia del trigémino
Authors: Torres Villacís María Paz , Zhune Gallegos Angie Heeyzarath , Monga Valdiviezo Kevin Alfredo , Celi González Odalys Estefanía
Published: September 2024

La neuralgia del trigémino es un trastorno neurológico caracterizado por episodios de dolor intenso y agudo en la zona inervada por el nervio trigémino, que incluye la cara, los dientes y las encías. Este dolor, a menudo descrito como punzante o similar a descargas eléctricas, puede ser desencadenado por estímulos leves, como tocar la cara, masticar o hablar. En la revisión bibliográfica sobre el uso de la toxina botulínica en el tratamiento de la neuralgia del trigémino, se recopilaron y analizaron estudios relevantes publicados hasta el 2024. Se identificaron artículos de revistas especializadas, tesis y trabajos de investigación que documentaron la eficacia y los mecanismos de acción de la toxina botulínica en pacientes con esta condición. Las conclusiones sobre el uso de la toxina botulínica en la neuralgia del trigémino indican que este tratamiento puede ser una opción efectiva para el manejo del dolor en pacientes que no responden adecuadamente a terapias convencionales. Los estudios revisados muestran que la inyección de toxina botulínica no solo reduce la intensidad del dolor, sino que también puede prolongar los períodos de alivio sintomático.
Rol de la enfermería en el manejo del paciente quirúrgico con comorbilidades: Desafíos y estrategias
Authors: Donoso Palomeque Myriam Susana , Cevallos Tapia Ana del Rocio , Espinel García Julia Teresa , Vélez Franco Madan Maricela
Published: September 2024

La disciplina enfermería brinda cuidados especializados al paciente que va a someterse a una intervención quirúrgica, ejecutando varias actividades coordinada con el resto de profesionales que forman parte del equipo quirúrgico que ayudarán significativamente en la culminación y éxito de la intervención quirúrgica .El objetivo de este trabajo es analizar el rol de la enfermería en el manejo del Paciente Quirúrgico con comorbilidades. Se llevó a cabo una revisión sistemática utilizando el la metodología PRISMA, que incluyo una búsqueda exhaustiva en diferentes fuentes de información académicas. Se seleccionaron varios estudios relacionados con el tema de revisión, cumpliendo con los criterios de inclusión, y se utilizó Mendeley como gestor bibliográfico. Concluyendo que la profesión de enfermería en la actualidad necesita cambiar su panorama enfocada en brindar cuidados de calidad y seguridad a los pacientes quirúrgicos, actuando con conciencia quirúrgica, lo que le permitirá aplicar correctamente las reglas y principios de asepsia y antisepsia ,por lo que el compromiso de enfermeras y enfermeros es proporcionar apoyo, asistencia, buen manejo de la tecnología y buenas actitudes que demuestren su condición humana, e ir aportando sus conocimientos a favor de los pacientes.
Tratamiento tópico para estomatitis subprotesis mediante la incorporación de acondicionador de tejidos y nistatina
Authors: Gavilanes Sánchez Carol Andrea , Egas Sánchez José Luis , Ortega Pow Hing Gipsy Paola , Bustamante Morán Víctor Hugo
Published: September 2024

La estomatitis de la dentadura postiza (DS) es un cambio patológico en la mucosa oral común en los usuarios de dentaduras postizas (DP), que se caracteriza por una reacción inflamatoria y eritema en la zona de la mucosa oral que entra en contacto con la dentadura. Hay 3 tipos de estomatitis de dentaduras postizas, a saber, lesiones hiperémicas puntuales tipo I (inflamación simple localizada), inflamación simple generalizada tipo 2, hiperplasia papilar inflamatoria tipo 3. En general, la DS se produce alrededor de la mucosa palatina. Los factores de riesgo como el traumatismo por oclusión por dentaduras postizas excesivas, la mala higiene bucal (OH), las malas condiciones sistémicas degenerativas y los malos hábitos como el tabaquismo aumentan la incidencia del DS. La descripción de las lesiones rojizas que se producen en la zona de la mucosa palatina sin síntomas de dolor intenso es uno de los signos clínicos del DS. La confirmación del diagnóstico de DS puede llevarse a cabo mediante un examen clínico, así como mediante un cultivo microscópico de tejidos. La reparación de las dentaduras postizas y la modificación de las condiciones de OH es una de las claves del éxito para acelerar la cicatrización del DS. Además, si hay candidiasis con una afección más grave, se pueden administrar fármacos antifúngicos tópicos en combinación con acondicionador de tejidos y sistémicos para recuperar la afección.
Fracaso en restauraciones adhesivas
Authors: Egas Sánchez José Luis , Ortega Rodríguez Danais Anniemari , Suasnabas Pacheco Erika Jazmín , Gavilanes Sánchez Carol Andrea
Published: September 2024

En un intento por esclarecer las técnicas utilizadas en las restauraciones adhesivas debido a la escasa literatura sobre el tema, se pretende, a través de una revisión de la literatura, analizar las principales causas de los fracasos de este tipo de procedimientos. A través de la revisión, todos los trabajos presentaron que las restauraciones de cerámicas consisten en una alternativa protésica muy interesante para la modificación de la forma de los dientes, posición en el tema de correcciones leves, corrección de defectos estructurales, modificación de color, rehabilitación oclusal, entre otras indicaciones. A menudo es posible devolver el equilibrio estético de la sonrisa con poco o ningún desgaste dental, lo que caracteriza el procedimiento como mínimamente invasivo y relativamente conservador, en comparación con las coronas totales que siempre requieren una mayor reducción de la estructura dental. Existen ciertos factores que son de gran importancia para el éxito y longevidad del procedimiento como la correcta indicación del tratamiento y la adecuada elección del material restaurador, seguido de la preparación dental; el uso de la técnica precisa, con el campo aislado y libre de cualquier contaminación.
Rehabilitación oral en el paciente con alteración de la dimensión vertical oclusal aplicando un enfoque multidisciplinario
Authors: Paredes Baidal María Fernanda , Valarezo Torres Juan José , Mejía Gallegos Cesar Gerardo , Lainez Aráuz Sofía Mirella
Published: September 2024

Uno de los temas de mayor controversia en el área odontológica son los referidos a la alteración de la dimensión vertical oclusal, dado que hasta la actualidad no existe un protocolo preciso para determinar esa medida para cada paciente. No obstante, se encuentran disponibles diversas propuestas de diferentes autores, soportadas por evidencia científica, que permiten al profesional tratante elaborar planes de tratamientos que garanticen los mejores resultados. El enfoque multidisciplinario en este tipo de rehabilitación ofrece la ventaja de integrar diferentes especialidades con la finalidad de proporcionar un tratamiento sistémico y la satisfacción del paciente. En consecuencia, el objetivo de la presente investigación se centra en la rehabilitación oral en el paciente con alteración de la dimensión vertical oclusal aplicando un enfoque multidisciplinario. El enfoque metodológico de la investigación es una revisión bibliográfico – documental. De la revisión se encontró, en primer lugar, que la evaluación y diagnóstico integral son fundamentales para la elección del plan de tratamiento. A partir del diagnóstico preciso se puede elaborar un plan de tratamiento personalizado que considere también las preferencias y el estilo de vida del paciente. Las opciones de tratamiento pueden incluir una combinación de ajustes de ortodoncia, procedimientos restaurativos y posiblemente intervenciones quirúrgicas. Además, la comunicación continua entre el equipo multidisciplinario es vital para adaptar el plan de tratamiento según sea necesario durante todo el proceso, garantizando que el paciente reciba la atención más adecuada y eficaz. Este enfoque individualizado en última instancia mejora la probabilidad de lograr resultados funcionales y estéticos óptimos para el paciente.
Evaluación y acreditación de la universidad ecuatoriana: desafíos y funciones
Authors: Plaza Criollo Luisana Isabel , Neira Sancho Mercy Soraya , Navarrete Lozada Clara Marlena , Cardenas Palacios Luis Efrén
Published: September 2024

La evaluación y acreditación de las universidades son fundamentales dado el impacto de estas en el desarrollo integral de los países. La acreditación es un proceso de reconocimiento de la calidad de programas e Instituciones de Educación Superior, que tiende a consolidarse en el mundo de manera autónoma y voluntaria. Para que la educación superior contribuya a identificar y solucionar los problemas de la sociedad, se requiere que sea pertinente y de calidad, es decir, que debe actuar con responsabilidad y compromiso en la creación, desarrollo y transmisión del conocimiento, en todas sus formas y, expresiones promoviendo su uso en todos los campos, enmarcándonos en el accionar de los cambios de las reformas en la enseñanza universitaria como respuesta a las nuevas necesidades sociales. En este sentido, la evaluación y acreditación juega un papel sumamente importante. El objetivo de la presente investigación se centra en plasmar las generalidades relacionadas con la evaluación y acreditación de la universidad ecuatoriana, con énfasis en su funcionalidad y desafíos. El enfoque metodológico de la investigación es una revisión bibliográfico – documental. Entre los aspectos funcionales del sistema de evaluación y acreditación de las IES en Ecuador, se encontraron el paso de un sistema cuantitativo a un sistema mixto, donde lo cualitativo cobra un valor importante, la conformación y fortalecimiento de los organismos involucrados en estos procesos, así como la creación de guías y manuales de procedimientos que permiten que el sistema se soporte en una estructura sólida. Asimismo, a pesar de que es un sistema reciente, su puesta en práctica durante estos años ha permitido que las universidades hayan tomado conciencia de la importancia de la autoevaluación, la evaluación externa y la acreditación de sus procesos. Ahora bien, en cuanto a los desafíos, uno de los principales, es la resistencia al cambio entre las instituciones educativas, lo cual plantea una barrera importante. A pesar de que un gran número de universidades han entendido la importancia de mejorar la calidad, muchas de ellas han establecido tradiciones y prácticas que pueden no alinearse con las demandas cambiantes del proceso de acreditación.
La nutrigenética: una oportunidad para la prevención y el tratamiento de enfermedades
Authors: López Gamboa Yoel
Published: September 2024

La nutrigenética emerge como un campo de estudio crucial en la búsqueda de estrategias personalizadas para la prevención y el tratamiento de enfermedades. Con el objetivo de establecer la relación que existe entre el consumo de nutrientes y la probabilidad de desarrollar enfermedades se desarrolló el presente trabajo con la intención de exponer el estado actual de la literatura científica en este sentido. Se desarrolló un estudio de revisión en los idiomas español, inglés y portugués en Scielo, PubMed, Google académico y Redalyc. Se utilizaron los siguientes términos de búsquedas: nutrigenética, nutrición de precisión y nutrigenómica. Se encontraron 68 artículos, de los cuales se estudiaron 31 por ajustarse con mayor precisión al objeto de estudio. La nutrigenética se fundamenta en la comprensión de cómo los genes individuales interactúan con los nutrientes que consumimos, marcando una relación estrecha entre la alimentación y la expresión genética. Este campo de estudio aborda cómo las variaciones genéticas entre individuos influyen en la manera en que sus cuerpos procesan y utilizan los nutrientes, lo que puede tener un impacto significativo en la salud y el desarrollo de enfermedades, siendo las más estudiadas la diabetes, obesidad y las enfermedades cardiovasculares.
The effect of early mobilization on constipation after abdominal surgery: A systematic review
Authors: Öztaş İsmail , Yava Ayla , Koyuncu Aynur
Published: September 2024

Background/Aim: Constipation can occur after abdominal procedures. In this study, we investigated whether early mobilization after abdominal surgery is effective for treating constipation.
Methods: We conducted a systematic review of studies implementing early and planned mobilization after abdominal surgical procedures. We extracted studies published from 2012–2022 from six electronic databases: PubMed, Google Scholar, Science Direct, Cochrane, TürkMedline, and Ulakbim. The data were collected by two reviewers following a pre-designed subtraction form. We made use of narrative synthesis when presenting our results.
Results: We examined 10 articles that satisfied the inclusion criteria; patients underwent a cesarean section in four studies, bariatric surgery (gastric bypass) in one study, liver resection in one study, radical cystectomy in two studies, cholecystectomy in one study, and a kidney transplant in one study. The studies were characterized by differences in the early mobilization programs applied to patients after abdominal surgery. In two of the studies, the patients were mobilized accordingly to daily step goals; in five studies only early stimulation and walking attempts were utilized. In three of the studies, the patients were mobilized within the scope of mobilization programs prepared in detail after surgery, and the targets were determined in terms of distance walked. All of the studies stipulated that physical activity should gradually increase over time.
Conclusion: Early and planned mobilization programs applied after surgery had positive effects on first gas/first stool output time, the severity of abdominal distension, the occurrence of nausea/vomiting, and the onset of oral intake.
‘Standing with Each Other’: Indigenous-Muslim Relation-Making on Turtle Island
Authors: Hossain Memona
Published: September 2024

Within the context of the northern part of Turtle Island, the space of relationships between Indigenous and Muslim communities is one intertwined within the history and geopolitical realities of settler-colonialism and immigration.  This paper is an exploration of the theme of space, and relationship formation from the perspective of Muslim and Indigenous peoples in Canada who have engaged in building relations over the past two decades.  This article is based on a wider qualitative semi-structured interview-based research project, supported by content analyses of existing literature and online resources produced by relevant organizations and initiatives. The research analysis has led me to thematically organize these spaces into four general types of spaces: 1) organization-led spaces of relationship building; 2) spaces of conviviality as pathways to relationship building; 3) relational spaces defined through acts of documentation; and 4) spiritually and emotionally bonded spaces that transcend a secular framework. This analysis led to identifying practices of relational meaning-making that form a preliminary understanding of what characterizes Indigenous-Muslim relations on Turtle Island.
Statistical analysis of multivariate binary time series based on a neural network model
Authors: Kharin Yu. S. , Shibalko S. A.
Published: September 2024

This article is devoted to the statistical analysis of multivariate binary time series. For solving this problem a parsimonious neural network model of Markov’s ergodic chain of order s was determined. Consistent statistical estimators for model parameters and estimation algorithms of parameters and forecasting algorithms of future states of time series were developed. The results of computer experiments on simulated and real data are presented.
Optical nanotransceivers in photonics
Authors: Gaponenko S. V. , Efimova T. A.
Published: September 2024

The analogy used in nanophotonics with radiophysics, on the basis of which the notion of an optical nanoantenna was introduced and fruitfully used, is extended to the case of two-step processes with optical excitation of a quantum emitter (scatterer) and subsequent emission of secondary photons and the concept of an “optical nanotransceiver” (transceiver), i. e. a device receiving primary and generating secondary photons is introduced. The nanotransceiver efficiency parameter is introduced, which is defined by the product of the primary radiation intensity factor and the local density of photonic states at the secondary radiation frequency. This nanotransceiver parameter determines scattered radiation intensity enhancement and a maximum possible value of photoluminescence enhancement. The latter is achieved for emitters with low intrinsic quantum yield.
Features of spectral characteristics of phenyl-containing vanadium (III) β-diketonates
Authors: Kostyuk N. N. , Diсk T. A. , Tsyhanau A. R.
Published: September 2024

Tris-dibenzoylmethanate ([V(dbm)3 ]) and tris-benzoylacetonate vanadium ([V(bac)3 ]) were obtained by electrochemical synthesis. The composition of chelates was determined using elemental analysis and IR spectral data. It was shown that the formation of a quasi-aromatic metallocycle, the main structural element of chelate, occurred as a result of electrolysis. At the same time, the batachromic shift of absorption bands of carbonyl groups was more than 100 cm–1. The overwhelming majority of absorption bands in the IR spectra of both compounds had mixed nature. For ([V(dbm)3 ] the characteristic of absorption bands did not exceed 13.5 %, and for [V(bac)3 ] – 10.3 %. The peripheral groups of ligands (phenyl and methyl) did not undergo transformation when influenced by electric current.
Supramolecular structure and thermal transformations of modified resinous-asphaltene substances
Authors: Yakavets N. V. , Krut’ko N. P. , Luksha O. V. , Sycheva O. A. , Kulbitskaya L. V.
Published: September 2024

A detailed study of the supramolecular structure of high molecular weight resinous-asphaltene substances (RAS) and the study of their stability to thermal-oxidative degradation processes in the presence of surfactants is a promising scientific direction and can become the basis for the development of additional oil treatment processes and, as a result, the intensification of thermal transformations of oil dispersed systems (ODS). In the work it has been established that the maximum modifying effect, which consists in reducing the amount of asphaltenes by 8–11 % and increasing the concentration of resins, saturated and aromatic hydrocarbons in the composition of the dispersion medium, is achieved by the interaction of ODS with octadecylpropylenediamine, alkyldiamine with the content of ethoxylated groups n = 3–6 and butyl coconut fatty alcohol ester with n = 10. This fact is due to a change in the geometric parameters of asphaltene nanoaggregates due to the adsorption of these surfactants on their surface. Thus, against the background of an increase in the interplanar distances of condensed aromatic layers dm from 3.66 to 3.85 Å and values of the intrachain distance from 5.71 to 5.80 Å, the average diameter of aromatic layers decreases by 0.67–2.36 Å and the average height of their pack by 1.52–2.64 Å, while the average number of layers in a pack is 5. Estimation of the results of thermal analysis indicates that the RAS thermograms have a similar form with three endoeffects with minima in the ranges of ~ 34.7–37.7 °C (I); 325.7–339.3 (II) and 434.8–438.7 °С (III) and one exoeffect with a maximum of ~ 460.5–475.3 °С (IV). With a decrease in the factor of crystallinity and aromaticity of RAS, their resistance to the processes of thermo-oxidative degradation in the temperature region of coke formation increases. The energy of thermal-oxidative destruction for modified systems by surfactants exceeds by 21.6 kJ/mol of this indicator for unmodified RAS and is 62.07 ÷ 66.13 kJ/mol.
Synthesis of functional derivatives of chlorine-substituted isothiazoles.
Authors: Margun E. N. , Kolesnik I. A. , Akishina E. A. , Dikusar E. A. , Logvinenko N. A. , Volchkov N. S. , Potkin V. I.
Published: September 2024

Optimal procedures have been developed for the synthesis of substituted isothiazoles containing an active chlorine atom in position 5 of the heterocycle and various functional groups in position 3: carboxyl, hydroxymethyl, aldehyde. Based on these methods, previously undescribed compounds were obtained: 5-morpholino-substituted 3-hydroxymethyl-4- chloroisothiazole, 4-chloroisothiazole-3-carboxylic acid and its methyl ester. The resulting substances are reactive building blocks for organic synthesis of compounds with a high potential for biological activity.
The effect of the liposomal form of alteplase on the effectiveness of thrombolysis in coronary arteries in acute myocardial infarction
Authors: Agabekov V. F. , Adzerikho I. E. , Vladimirskaya T. E. , Dubatouka K. I. , Zhilkevich A. V. , Lutsik I. N.
Published: September 2024

A liposomal (Lip) formulation of tissue plasminogen activator, alteplase (AlT), has been developed. The quantitative and qualitative composition of the liposomes, as well as their physicochemical properties and proteolytic activity, have been studied in relation to the thrombolytic liposomal form. It was determined that a formulation consisting of liposomes with a phosphatidylcholine/cholesterol ratio of 1.5 : 1, and lipids/alteplase ratio of 1 : 1, is optimal for treating acute myocardial infarction (AMI) in experimental models. At different component ratios, liposomes had a negative zeta potential value greater than 30 mV, indicating their aggregative stability, even after storage for two days at 20 degrees Celsius. Liposomes derived from soy phosphatidylcholine showed greater colloidal stability with a zeta potential of approximately –57 mV and a lower hydrodynamic diameter of approximately 140 nanometers, compared to liposomes derived from egg phosphatidylcholine, which had a zeta potential around –35.4 mV and a hydrodynamic diameter around 220 nanometers. The initial content of free AlT in the liposome supernatant from egg phosphatidylcholine (Lipeg) was 15.0 ± 4.0 %. During the incubation period of 4 days, the concentration of free AlT decreased to 9.0 ± 4.5 %. In contrast, in liposomes derived from soy phosphatidylcholine (LipS), the content of free AlT increased from 11.0 ± 4.5 % to 32.5 ± 6.0 % over the same incubation period. The value of the proteolytic activity of tissue plasminogen activator (tPA) in the compositions of Lipeg(AlT) and Lips (AlT) depends on the type of phosphatidylcholine. The initial tPA activity in Lipeg (AlT) was 36.0 %, and after 1 day, it increased to 45 %. In Lips (AlT), the initial activity was 61.0 % and increased to 66 % after 1 day. When using the liposomal form of alteplase for delivery into the coronary arteries of rats with acute myocardial infarction (AMI), a more complete fibrin lysis is noted compared to animals receiving the native form of the drug. The developed system of targeted delivery of alteplase using soy liposomes has been shown to significantly improve the degree of coronary artery lumen restoration by more than 15 %, compared to the use of a conventional drug (p < 0.05).
IR-spectroscopic analysis of interaction with multi-layer paper and cardboard containing synthetic fibers with printing inks
Authors: Eshbaeva U. J. , Djalilov A. A.
Published: September 2024

An IR spectroscopic analysis of the printing and technical properties of new types of multilayer packaging paper and cardboard containing waste polyacrylonitrile fiber and their interaction with printing inks was carried out. The preference for using multilayer composite paper and cardboard for the printing and paper industries is shown. It has been established that the tensile strength of paper does not depend on the strength of individual components, but on the strength of the paper structure formed during its production. When the paper contained 20% waste modified polyacrylonitrile, maximum optical density was achieved with a minimum thickness of the ink layer, that is, saturated prints were obtained with minimal consumption of printing ink.
Application of neurophysiological studies for diagnosis and justification of neurosurgical treatment of kyphotic deformity due to the congenital anomaly of the spine
Authors: Soshnikova E. V. , Ilyasevich I. A. , Tesakov D. K. , Gerasimenko M. A. , Pustovoitov K. V.
Published: September 2024

The results of a comprehensive clinical, radiological and neurophysiological study were analyzed in patients with kyphotic deformity of the thoracic and lumbar spine due to a congenital anomaly of vertebral development in the dynamics of surgical treatment. It has been established that congenital kyphotic spinal deformity is accompanied by vertebromedullary conflict with a high risk of the occurrence and/or worsening of spinal neurological disorders. The study of the data obtained made it possible to evaluate deformation lesions of the spine from the standpoint of qualitative and quantitative severity of pathological changes in the conduction function in the system of nervous tracts of the spinal cord, which was an objective argument in justifying the indications for surgical correction and its methodological implementation, as well as an important neurophysiological criterion for subsequent dynamic monitoring of clinical conditions of a patient.

It was found that the surgical treatment allowed us to improve and subsequently stabilize the functional state of the spinal cord as a consequence of the achieved significant correction of congenital kyphotic spinal deformity.
Experimental modeling of the choledochojunoanastomosis stricture
Authors: Arlouski Yu. N. , Gain Yu. M. , Vladimirskaya T. E. , Yuraga T. M. , Chernov O. N.
Published: September 2024

As a result of experimental modeling of the choledochojejunostomy stricture n laboratory animals, the role of specific biomarkers in establishing the causes of excessive scarring of biliodigestive anastomoses was revealed. The proposed model is suitable for studying the phase nature of the pathological process and the pathogenesis of development of the choledochojejunostomy stricture, allowing one to outline ways how to prevent its formation in a clinical setting.
Free amino acid pool in the rat skin and the skin morphological structure in acute allergic contact dermatitis
Authors: Chumachenko M. S. , Korik E. O. , Rjabceva S. N. , Semak I. V.
Published: September 2024

The concentration of free amino acids in the skin of rats in experimental acute allergic contact dermatitis (ACD) was studied. Free AAs were determined by reverse-phase high-performance liquid chromatography. Acute ACD was simulated using 2.4-dinitrochlorobenzene. The levels of asparagic and glutamic acids, valine, leucine, phenylalanine, lysine, and taurine increased and methionine, tyrosine, tryptophan, α-aminobutyric acid and anserine decreased in the rat skin during acute ACD development. An imbalance of amino acid metabolism was expressed in an increase in the ratio of aromatic amino acids/branched-chain amino acids by a decrease in the sum of aromatic amino acids. An increase in the Phe/Tyr ratio may indicate a decrease in the activity of the hydroxylase pathway of phenylalanine metabolism in the rat skin. Only in the skin of rats with acute ACD, the levels of valine, isoleucine and lysine were negatively correlated with the level of blood TNF-1α, which confirms their anti-inflammatory effect.

Histological examination revealed an inflammatory reaction expressed by lymphocytic infiltration of various skin layers (ectoderm, subepidermal layer). Perivascular proliferation of fibroblasts and formation of subepidermal fibrosis were observed in subepithelial sections. The upper layer of the thorny layer was necrotic, the granular layer with necrosis and pronounced karyopiknosis of nuclei was observed. The epidermis thickness increased, infiltration of lymphocytes and segmented neutrophils into epidermis was noted up to the cells of the thorny layer (exocytosis).

The data obtained indicate a significant metabolic imbalance of amino acids in the skin of rats in acute ACD, manifested by depletion of the amino acid pool of aromatic and sulfur-containing amino acids, impaired metabolism of phenylalanine, as well as increased levels of immunogenic amino acids that play a functional role in the regulation of anti-inflammatory, antioxidant system and proliferative activity of immune system cells on the background of a significant inflammatory process.
Neuronal Activity Topography Reveals Neuronal Change in Comatose Patients Treated by tDCS.
Authors: Takahashi Chiaki , Shibata Takashi , Tanaka Mieko , Watanabe Yuri , Kobayashi Yohei , Matsushita Isao
Published: September 2024

BACKGROUND: In our hospital, transcranial direct current stimulation (tDCS) is applied in combination with occupational therapy (OT) for patients with persistent consciousness disorders. There have been reports from some research groups on Left dorsolateral prefrontal area (F3) anodal stimulation as wells as Frontal pole (Fpz) anodal stimulation under different conditions. We chose either anodal stimulation site depending on the patient's condition. CASES: Nine patients underwent tDCS with Fpz or F3 anodal stimulation for 10 days, followed by a 2-day break, after which the stimulation sites were switched, and the patients were stimulated for another 10 days. Their Electroencephalography changes were evaluated by using visual images of neuronal activity topography (NAT). The asymmetry index (AI) was also calculated to compare lateral differences in neuronal changes in the frontal lobe. Seven out of nine cases started with Fpz anode, and two with F3 anode. In the former setting, six cases improved, two aggravated and one remained unchanged. In the latter, one case unchanged and one remained aggravated. After applying tDCS, NAT and AI of the improved cases showed a tendency to approximate the normal control group. Discussion: Among these cases, all but one showed improvement in CRS-R scores, especially in Fpz stimulation. Additionally, changes in the scores indicated that most cases showed improvements in responses to visual and auditory stimulation. Furthermore, the NAT system allows for the rapid and minimally invasive assessment of changes in neuronal activity. Consequently, it is suggested that this system may be valuable for evaluating the therapeutic effects of tDCS and identifying effective stimulation sites.
A Musicoterapia sob a ótica de graduando em Enfermagem: Uma reflexão acerca de suas vivências pessoais
Authors: Sousa Joab Gomes da Silva , Silva Leila Araújo da , Siebra Isabela Rocha , Sousa Neto Argemiro José de
Published: September 2024

Saúde mental e qualidade de vida são aspectos fundamentais quando se refere aos estudantes de enfermagem e aos comportamentos relacionados às adaptações vivenciadas, sendo a universidade um ambiente que o estudante atribui valores a sua vida profissional e pessoal. No entanto, as práticas complementares não medicamentosas podem ser auxílio, defendendo o cuidado integral ao indivíduo. A musicoterapia é um recurso terapêutico dentre as práticas, envolvendo aspectos emocionais, induzindo o indivíduo a perceber-se em sua singularidade. O estudo tem como objetivo principal conhecer a percepção de acadêmicos de enfermagem sobre a musicoterapia e a relação com o seu bem-estar. Este estudo caracteriza-se como uma pesquisa do tipo exploratório descritivo com abordagem qualitativa. Os dados foram coletados entre os meses de março e abril de 2020, por meio de um roteiro de perguntas subjetivas, sendo realizados por meio de um link através de um questionário eletrônico online no Google Forms devido à pandemia, a fim de manter o distanciamento entre pesquisador e participante, os estudantes responderam as perguntas após o aceite da pesquisa pelo Termo de Consentimento Livre e Esclarecido. Após a aprovação do estudo, o mesmo foi submetido ao Comitê de ética em pesquisa – CEP, por meio da plataforma Brasil. A partir dos dados coletados foi possível identificar a concepção de acadêmicos de enfermagem tendo em vista o efeito da musicoterapia nas sobrecargas psicológicas, sendo apresentadas características sócias demográficas dos participantes da pesquisa, em seguida aborda-se em categorias a inserção na vida acadêmica e sobrecargas geradas pela mudança de rotina e o uso da música com eficácia terapêutica na rotina dos acadêmicos. Diante disso, vale ressaltar a importância do desenvolvimento de mais estudos sobre a temática em questão, pois a música pode ser trabalhada de forma terapêutica proporcionando benefícios a saúde.
Educação, metodologias ativas e gestão
Authors: Sousa Maiara Gadelha de , Holanda Magno de Souza , Santos Filho Humberto Nascimento Dias
Published: September 2024

Livro
Empirical Analysis of Sustainable Performance in Relation to Stock Exchange Performance: Evidence from Romania
Authors: Tiscenco Vilena , Grosu Veronica , Bădicu Galina , Cosmulese Cristina Gabriela
Published: September 2024

Given the substantial advancements in worldwide financial markets and the sharp increase in sustainability concerns, this article proposes an incursion into the empirical analysis of the interaction between companies' sustainable performance and stock market performance, focusing on the specificities of the Romanian financial market. It emphasizes the importance of a comprehensive approach that goes beyond simple financial figure analysis to include aspects such as sustainability, corporate governance, and social impact. The article aims to shed light on this complex relationship through rigorous empirical analysis applied to data specific to the Romanian market. We will thoroughly investigate the connections between companies' sustainability practices and the evolution of stock prices, taking into account the economic particularities of Romania, culminating with the estimation of a multiple linear regression model. Our study reveals that there is a correlation between the market capitalization of a company, its corporate performance and the specific industry or sector in which it operates.
The Impact of Urbanization on Energy Consumption In South Africa: An Empirical Investigation
Authors: Vacu-Ngqila Nomfundo Portia , Odhiambo Nicholas Mbaya
Published: September 2024

The purpose of this paper is to examine the impact of urbanization on energy consumption in the case of South Africa. To empirically estimate this, the study employed the autoregressive distributed lag (ARDL) approach and annual time series data covering the period from 1983 to 2021. In this study, urbanization and energy consumption are measured through the total urban population as a share of the total population and total energy consumption per capita, respectively. The findings from the ARDL cointegration test confirm that an increase in urbanization leads to a short-run increase and a long-run decrease in energy consumption. The results further confirm that an increase in economic growth leads to a long-run and short-run increase in energy consumption. It was also found that financial development leads to a long-run increase in energy consumption, while its first lagged values lead to a short-run decline. Foreign direct investment was found to have no significant impact on energy consumption both in the long run and short run.
A Study on Post-Taukte (Cyclone) Impact on Economic Recovery of People of Jafrabad City
Authors: Gandhi Kalpesh P. , Shilu Viralkumar M. Shilu
Published: September 2024

Natural calamities have always been disastrous for the people who are affected by it. Taukte cyclone had hit Sourthern Saurashtra area of Gujarat state on 17th May 2021. Through this research paper, researchers have tried to find the loss of assets and loss of income of people of Jafrabad city, which is situated on costal area of Arabian Sea due to devastating effect of Taukte. This study focuses on recovery period of the damaged assets and normalization of income of affected people. A structured questionnaire used to collect the primary data from 433 respondents of this region. It was the challenging task for researchers to collect data from the respondents as they could not balm their wounds, however the main purpose of this study is to analyse recovery period with regard to assets and income of the people of this badly affected area. To know the association with demographic variables, Chi-square technique has been used by the researchers. It has been found that there is no significant association for recovery period for assets and gender and occupation of the respondents while for recovery period of income gender has association but occupation does not have association.
Fiscal - Economic Perspectives in Promoting Sustainable Development of National Economies
Authors: Grosu Veronica , Melega Anatol , Tulvinschi Mihaela
Published: September 2024

In recent years, sustainable development has become a topic of major interest, aiming not only at economic growth, but also at enhancing social welfare and protecting the environment. The aim of this research is to analyse the role of taxation in promoting sustainable development and to assess how taxes affect the economy, the environment and society. The study is based on data collected from 163 national economies and uses statistical methods to examine the impact of the tax burden on sustainable development in national economies. The results show that tax dynamics significantly influence economic growth, the sustainability of national economies and social welfare. Furthermore, the article highlights the importance of tax policy in achieving sustainable development goals and suggests adopting a balanced approach to taxation that takes into account economic, social and environmental aspects. This research contributes to expanding knowledge in the field of sustainable development of national economies, providing a new perspective on the relationship between sustainable development and the tax burden.
Globalization and Inflation Nexus in South Africa: An Empirical Investigation
Authors: Musakwa Mercy T T , De Jenga Mmathapelo
Published: September 2024

The impact of globalisation on inflation is investigated for South Africa using annual time series data from 1990 to 2022. The study was motivated by the need to establish if the notion that globalisation leads to a decrease in prices in the domestic economy still holds water for South Africa. The study employs ARDL to explore the nature of the relationship between globalisation and inflation. Using trade openness as a measure of globalisation and the rate of change of the consumer price index as a measure of inflation, the study found globalisation to worsen inflation pressures in South Africa irrespective of the timeframe considered. Thus, South African authorities need to put measures in place to reduce the impact of globalisation on price levels. Policy implications are discussed
Bibliometric Insights into TV Advertising Research: Trends, Challenges, and Continued Relevance in the Digital Age
Authors: Nichifor Bogdan , Zaiț Luminița , Timiras Laura
Published: September 2024

Bibliometric analysis has been employed for several years across various fields to identify the existing body of science related to a specific discipline or topic. However, such a research approach has not been applied to TV advertising. This article proposes the use of bibliometric analysis to discern trends in research activity related to TV advertising. The motivation for this approach stems from the fact that traditional media advertising is currently facing "pressure" from online platforms. This pressure is evident not only from the perspective of companies and their communication strategies but also in terms of research emphasis. We sought to determine whether researchers still maintain an interest in this subject. Through our analysis, we found that TV advertising remains a topic of interest for researchers. Moreover, their focus aligns with a pragmatic philosophy, emphasizing areas such as impact, communication, media, and consumption – topics that are crucial when deliberating about budgets and communication ROI.
The Demographic Profile of The Population in Small, Medium and Large-Sized Cities in Romania
Authors: Stângaciu Oana-Ancuța , Harja Eugenia
Published: September 2024

The present study analyzes the demographic profile of the population by categories of urban localities, categories established according to the number of inhabitants, respectively very small, small, medium and large-sized cities. The main conclusions from this study would be that approximately 40% of the Romanian population lives in medium and large cities, the average age of the population in very small and small towns is lower than that in larger cities, the share of the population whose domicile coincides with residence is higher in smaller cities compared to larger ones, and the distribution of the main ethnicities highlights a slightly asymmetric territorial distribution within the Hungarian ethnic group (there are localities with very high percentages of this ethnic group) and a symmetrical distribution for the Romany ethnic group.
Wastewater treatment in the pulp and paper industry: A review
Authors: Yung-Tse Hung  , Emersen Liauw  , Howard H. Paul  , Christopher R. Huhnke
Published: September 2024

The pulp and paper industry plays a large role in global manufacturing, which creates significant water consumption and generation of wastewater that is filled with organic compounds and other chemicals. This paper will explore many different aspects of the pulp and paper industry such as raw material sourcing, manufacturing processes, environmental concerns, technological advancements, and the various wastewater treatment approaches. While there are many different methods to approach this wastewater issue, in this paper we will focus on anaerobic digestion, the application of biological aerated filters, and the use of constructed wetlands. The main material utilized in this industry is wood pulp, which undergoes multiple different procedures and processes to create the typical paper products we use every day. These processes, such as pulping and bleaching, create a large number of environmental concerns despite efforts to encourage better manufacturing practices and paper recycling.
Measuring the impact of green packaging on consumer purchase intention: A study on selected convenience goods in Banglades
Authors: Md Zahid Hasan  , Md. Oliul Islam  , Shamima Easmin Shanta
Published: September 2024

The fundamental accomplishment of moving towards the green concept is the use of green packaging in a product. With the growing worldwide environmental concerns, green practices like green packaging have become more important for businesses and consumers worldwide. This study was intended to identify the key factors that actually help enhance the buying intention of consumers towards green packaged convenience goods in terms of mini-pack shampoo, chips, and wallet tissue in Bangladesh. Based on previous research and fieldwork, a total of five (5) attributes have been chosen for the study. The survey was conducted using a self-structured questionnaire, with data collected from 150 respondents among the users of green packaging via the convenience sample approach. This study’s reliability, validity, regression, and correlation have been tested with the help of SPSS (version 21). The findings of this study examined that the variables named environment concern, environmental knowledge of green packaging, green trust, and availability have positive impact on consumers’ purchase intention towards green packaged convenience items in terms of mini-pack shampoo, chips and wallet tissue. On the other hand, the variable named price has a negative impact on consumers’ purchase intention towards green packaged convenience goods in the prospects of mini-pack shampoo, chips, and wallet tissue. The results presented have significance for national policymakers, product and package designers in Bangladesh, and marketers therein for creating compelling and successful marketing strategies for eco-friendly packaging that appeals to consumers' subconscious needs.
Ethno veterinary practices for cattle amongst traditional veterinary health care practitioners in palayamkottai, tirunelveli, tamilnadu
Authors: P.Kamali  , A.Muneeswaran
Published: September 2024

In the Palayamkottai, tirunelveli in tamilnadu, people make extensive use of medicinal plants to treat a number of diseases in cattle. The aim of the study was to identify the medicinal plants used to treat various ailments in cattle. Ethno veterinary survey was carried out using questionnaire and individual interviews from June to July 2024 in Palayamkottai, Tirunelveli district, Tamilnadu. The study identified total of 53 plants species divided into 31 families used in the various cattle ailments such as Foot and Mouth Disease, Dysentery, Mastitis, wound, bleeding horns, abscess, to improve milk production, pain and contusion due to trauma in Cattle by traditional veterinary health care practitioners. 16 internal and external applications are prepared by using these species. Species from the Fabaceae, Poaceae and Lamiaceae families are the most widely represented. Leaves, seeds, fruits and roots are the most commonly used parts. The results of the study provided all relevant information, particularly Ingredients, mode of preparation and route of administration.
Extra-pulmonary manifestations of COVID-19: A comprehensive review
Authors: Eghbal Lahooran  , Oilinia Bordovski  , Bonesch Tiora
Published: September 2024

The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has predominantly been recognized for its respiratory impact. However, as the pandemic has progressed, it has become evident that SARS-CoV-2 affects multiple organ systems beyond the lungs, resulting in a wide array of extra-pulmonary manifestations. These manifestations encompass cardiovascular, neurological, gastrointestinal, hepatic, renal, dermatological, hematological, endocrine, musculoskeletal, ocular, immunological, and psychiatric complications. This review aims to provide a comprehensive understanding of these extra-pulmonary manifestations, highlighting their clinical significance, underlying mechanisms, and implications for patient management. Recognizing these manifestations is critical for improving patient outcomes and informing ongoing research and therapeutic strategies.
Computer Vision Promising Innovations
Authors: David Shamoo Excel
Published: September 2024

Computer vision, an interdisciplinary field bridging artificial intelligence and image processing, seeks to bestow machines with the capability to interpret and make decisions based on visual data. As the digital age propels forward, the ubiquity of visual content underscores the importance of efficient and effective automated interpretation. This paper delves deeply into the modern advancements and methodologies of computer vision, emphasizing its transformative role in various applications ranging from medical imaging to autonomous driving. With the increasing complexity of visual data, challenges arise pertaining to real-time processing, scalability, and the ethical implications of automated decision-making. Through an exhaustive literature review and novel experimentation, this research demystifies the multifaceted domain of computer vision, elucidating its potential and constraints. The study culminates in a visionary outlook, highlighting future avenues for research, including the fusion of augmented reality with computer vision, novel deep learning architectures, and ensuring ethical AI practices in visual interpretation.
Blockchain Beyond Cryptocurrencies: An Exploration of Potential Applications
Authors: David Shamoo Excel
Published: September 2024

Blockchain technology, primarily acclaimed for its instrumental role in underpinning cryptocurrencies, has seen rising prominence in a multitude of applications outside the digital currency realm. Its decentralized infrastructure coupled with cryptographic integrity offers solutions to longstanding challenges across various industries, including supply chain, healthcare, and finance. This research endeavor delves into these multifarious applications, providing insights into the potential benefits and the existing impediments in the broader adoption of blockchain technology.