bluuebunny/crossref_metadata_2025 huggingface dataset:
Deep Learning Unravels Differences Between Kinematic and Kinetics Gait Cycle Time Series from Two Control Samples of Healthy Children Assessed into Two Different Gait Laboratories
Authors: Álvarez de Miranda Alfonso De Gorostegui , Kiernan Damien , Martín-Gonzalo Juan-Andrés , López-López Javier , Pulido-Valdeolivas Irene , Rausell Estrella , Zanin Massimiliano , Gómez-Andrés David
Published: December 2024

We investigate the application of deep learning in comparing gait cycle time series from two groups of healthy children, each assessed in different gait laboratories. Both laboratories used similar gait analysis protocols with minimal differences in data collection. Utilizing a ResNet-based deep learning model, we successfully identified the source laboratory of each dataset, achieving high classification accuracy across multiple gait parameters. To address inter-laboratory differences, we explored various preprocessing methods and time series properties that may be detected by the algorithm. We found that standardization of time series values was a successful approach to decrease the ability of the model to distinguish between the two centers. Our findings also reveal that differences in the power spectra and autocorrelation structures of the datasets play a significant role in model performance. Our study emphasizes the importance of standardized protocols and robust data preprocessing to enhance the transferability of machine learning models across clinical settings, particularly for deep learning approaches.
Left Ventricular Hypertrabeculation (LVHT) In Athletes: Negligible Finding?
Authors: Jagminas Rokas , Šerpytis Rokas , Šerpytis Pranas , Glaveckaitė Sigita
Published: December 2024

Left ventricular hypertrabeculation (LVHT) used to be a rare phenotypic trait. With advances in diagnostic imaging techniques, LVHT is being recognised in an increasing number of people. The scientific data shows a possibility of over-diagnosing this cardiomyopathy in a population of people who have very high physical activity. We described the case of a young athlete with no medical history who presented with syncope during a marathon running race. Initial evaluation showed elevated troponin I, transthoracic echocardiography showed a trabeculated ventricle and subsequent cardiac magnetic resonance (CMR), revealed left ventricular hypertrabeculation (LVHT). During subsequent evaluation by tilt table testing, vasovagal syncope was identified as the likely aetiology of syncope. The patient was advised to cease sports and stimulants like caffeine use. At the 29-month follow-up, CMR showed normalisation of the non-compacted to compacted myocardial ratio and improvement in left ventricular function, with no further syncopal episodes reported. This is an example of physiologic hypertrabeculation of the LV apex in a recreational endurance athlete with normalisation of non-compacted to compacted myocardial layer ratio after detraining. Physiologic hypertrabeculation, a benign component of exercise-induced cardiac remodelling, must be differentiated from noncompaction cardiomyopathy and other pathologies causing syncope. This case underscores the importance of distinguishing physiologic hypertrabeculation from pathological LVHT in athletes, highlighting that exercise-induced cardiac remodelling can normalise with detraining.
Application of Graph Theory and Variants of Greedy Graph Coloring Algorithms for Optimization of Distributed Peer-to-Peer Blockchain Networks
Authors: Švarcmajer Miljenko , Ivanović Denis , Rudec Tomislav , Lukić Ivica
Published: December 2024

This paper investigates the application of graph theory and variants of greedy graph coloring algorithms for the optimization of distributed peer-to-peer networks, with a special focus on private blockchain networks. The graph coloring problem, as an NP-hard problem, presents a challenge in determining the minimum number of colors needed to efficiently allocate resources within the network. The paper deals with the influence of different graph density, i.e. the number of links, on the efficiency of greedy algorithms such as DSATUR, Descending and Ascending. Experimental results show that increasing the number of links in the network contributes to a more uniform distribution of colors and increases the resistance of the network, whereby the DSATUR algorithm achieves the most uniform color saturation. The optimal configuration for a 100-node network has been identified at around 2000 to 2500 links, which achieves stability without excessive redundancy. These results are applied in the context of a private blockchain network that uses optimal connectivity to achieve high resilience and efficient resource allocation. The research findings suggest that adapting network configuration using greedy algorithms can contribute to the optimization of distributed systems, making them more stable and resilient to loads.
Contextual Analysis of Financial Time Series
Authors: Yarushkina Nadezhda , Filippov Aleksey , Romanov Anton
Published: December 2024

Today, problems of the evaluation of the financial state of small and medium-sized companies are actual. We propose a novel approach for the evaluation of the company financial state, that realized as a module of a decision support system. The proposed component is based on fuzzy logic and knowledge engineering. We present a model of ontology to form the context of data analysis and financial time series modeling. The ontological context allows to represent trends of the analyzed financial state indicators. An expert can add a set of fuzzy rules to the ontology for the creation of the control systems based on the fuzzy inference. The proposed approach allows reducing the time of analysis and interpretation of the results. Experimental results confirm the correctness and effectiveness of the approach proposed in this article.
Environmental Management and Decarbonization Nexus: A Pathway to Energy Sector’s Sustainable Futures
Authors: Mohamed Abdel Mohsen , Mohamed Dina , Fayad Ahdam , Al Nahyan Moza
Published: December 2024

This paper explores the intricate relationship between environmental management and decarbonization, demonstrating how these two areas can be effectively integrated to produce a wide-ranging framework for sustainability. The paper discusses the environmental management and decarbonization nexus towards sustainable futures in the energy sector through the conversion to green technologies, energy efficiency, and carbon capture, storage and utilization (CCSU) innovative technologies and infrastructures. In doing so circular economy principles, low GHGs emissions production processes, and CCSU strategies are emphasized. The outcomes of the paper include identifying actionable steps and policy recommendations that support environmental management and decarbonization nexus in the energy sector. By illustrating the benefits of this nexus, the paper provides insights into how governments, industries, and communities can collaborate to implement decarbonization measures that not only reduce GHGs emissions but also support environmental sustainability and social welfare.
Evaluating Ecosystem Characteristics and Ecological Carrying Capacity for Marine Fauna Stock Enhancement within a Marine Ranching System
Authors: Feng Jie , Yu HaoLin , Wu Lingjuan , Yuan Chao , Zhao Xiaolong , Sun Huiying , Cheng Cheng , Li Yifei , Sun Jingyi , Li Yan , Wang Xiaolong , Shang Yongjun , Xu JiangLing , Zhang Tao
Published: December 2024

China has recently launched extensive marine ranching projects, highlighting the need for scien-tific evaluation of ecosystem structure and function to guide their development. This study estab-lished two energy flow models and an evaluation index system to assess the structure, function, carrying capacity, and ecological status of both a marine ranching ecosystem and a nearby control site in the Beibu Gulf. The results showed that the ranching ecosystem outperformed the control ecosystem in terms of food chain length, system size, and the ecological carrying capacity of eco-nomically important species. The ranching ecosystem was classified as "relatively good," while the control ecosystem was deemed "relatively poor," confirming the success of the ranching efforts. Mussels, large crabs, and Scorpaenidae were identified as key species for stock enhancement based on their biomass potential. Scenario simulations using Ecosim, driven by biomass and fishing factors, indicated that stock enhancement strategies targeting MOB (mussels, oysters, and barna-cles) significantly improved the ranching ecosystem, raising its status to "good." However, the simulations also revealed that stock enhancement had limited effects on optimizing food web structure, system organization, and energy transfer efficiency, suggesting that a combination of strategies is necessary for further improvement.
Urtica dioica L. Leaf Extract Dose-Dependently Modulates Oxidative Stress in the Kidney and Exerts Anti-Fibrotic and Anti-Inflammatory Properties by the Molecular Mechanisms Independent of NRF-2 Signalization Mirroring the Effects of Losartan in SHR
Authors: Vajic Una -Jovana , Mihailovic-Stanojevic Nevena , Karanovic Danijela , Zivotic Maja , Ivanov Milan , Jovovic Djurdjica , Grujic-Milanovic Jelica , Miloradovic Zoran
Published: December 2024

Background: Previously, we confirmed systemic antihypertensive and antioxidant properties of Urtica dioica L. leaf extract (UE) in spontaneously hypertensive rats (SHR). Here, we aimed to evaluate whether UE can alter the NO and Nrf-2 signalling to prevent local oxidative stress and kidney damage in the model of essential hypertension. Methods: SHR were divided into 5 groups: SHRC- control, received 0.5 mL/day of water, SHR+L received 10 mg/kg/day of losartan, SHR+UE10, SHR+UE50, and SHR+UE200 received 10, 50, and 200 mg/kg/day during next 4 weeks. At the end of the experiment, urine samples were collected for albuminuria and nitrate/nitrite assessment. Mean arterial pressure (MAP) was measured, and blood samples were collected for plasma creatinine evaluation. Kidneys were analysed for nitrate/nitrite, oxidative stress, and target molecules by biochemical, Western blot and immunofluorescent techniques. Results: Losartan and UE50 significantly reduced MAP, albuminuria, oxidative stress, fibroinflammatory markers, and NRF-2/CAT/SOD signalling, with a significant increase of 6-nitrotryptophan and eNOS expressions compared to control. The effects of UE showed dose dependence. Conclusions: Beneficial effects of UE and losartan were independent of NRF-2 signalization in SHR. Interestingly, all treatments induced the increase of 6-nitrotryptophan expression, thus further studies are needed to elucidate the mechanisms of such nitrated tryptophan.
Beneficial Antioxidant Effects of Coenzyme Q10 in In Vitro and In Vivo Models of CDKL5 Deficiency Disorder
Authors: Loi Manuela , Valenti Francesca , Trazzi Stefania , Mottolese Nicola , Candini Giulia , Bove Angelica Marina , Trebbi Federica , Pincigher Luca , Fato Romana , Bergamini Christian , Medici Giorgio , Ciani Elisabetta
Published: December 2024

CDKL5 deficiency disorder (CDD), a developmental encephalopathy caused by mutations in the cyclin-dependent kinase-like 5 (CDKL5) gene, is characterized by a complex and severe clinical picture, including early-onset epilepsy, cognitive, motor, visual, and gastrointestinal disturbances. This disease still lacks a medical treatment to mitigate, or reverse, its course, and improve the patient’s quality of life. Although CDD is primarily a genetic brain disorder, some evidence in-dicates systemic abnormalities, such as the presence of a redox imbalance in plasma and skin fi-broblasts from CDD patients and in cardiac myocytes of a mouse model of CDD. In order to shed light on the role of oxidative stress in the CDD pathophysiology, in this study we aimed to in-vestigate the therapeutic potential of Coenzyme Q10 (CoQ10), which is known to be a powerful antioxidant, using in vitro and in vivo models of CDD. We found that CoQ10 supplementation not only reduces levels of Reactive Oxygen Species (ROS) and normalizes glutathione balance, but also restores the levels of markers of DNA damage (γ-H2AX) and senescence (lamin B1), significantly improving cellular proliferation and survival in a human neuronal model of CDD. Importantly, oral supplementation with CoQ10 exerts a protective role toward lipid peroxidation and DNA damage in the heart of a murine model of CDD, the Cdkl5 (+/−) female mouse. Our results highlight the therapeutic potential of the antioxidant supplement CoQ10 in counteracting the detrimental oxidative stress induced by CDKL5 deficiency.
Ecotoxicity of a Representative Urban Mixture of Rare Earth Elements to Hydra vulgaris
Authors: Auclair Joelle , André Chantale , André Eva , Gagné François
Published: December 2024

The aquatic toxicity of realistic mixtures of rare earth elements (REE) is less understood. The purpose of this study was to examine the sublethal and lethal toxicity of an environmentally realistic mixture of five REE in Hydra vulgaris. The REE mixture was composed of 5 elements (Gd, Ce, Nd, Yb and Dy with a total REE loading of 13.7 µg/L) that were found in 6 municipal effluents at the same concentration ratios (1X). The organisms were exposed to increasing concentrations (0.5, 1, 5, 10, 25, 50 and 100X) of the mixture for 96 h at 20oC. The lethal and sublethal toxicity was evaluated by morphological changes and the gene expression (mRNA) involved in oxidative stress, damaged protein salvaging (autophagy), regeneration, neural activity and oxidated DNA repair. The data revealed that the total REE concentration of the environmental mixture was well below the potential toxicity of REE, which occurs generally at concentrations > 200 ug/L. At the gene expression levels, effects occurred at concentrations below those reported in municipal effluents suggesting that these REEs could produce toxic effects on the long-term in hydra close to municipal effluent discharges.
Poly(acrylic acid)/TiO2 Nanocomposite Hydrogels for Paper Art Work Cleaning and Protection
Authors: Botti Sabina , Bonfigli Francesca , D'Amato Rosaria , Rodesi Jasmine , Santonicola Maria Gabriella
Published: December 2024

Paper-based artworks are prone to natural aging processes driven by chemical and biological mechanisms. Numerous cleaning, disinfecting, and protective treatments have been developed to mitigate deterioration and prevent irreversible damage. In this context, the application of hydrogels as support materials has gained widespread attention due to their efficacy in enabling minimally invasive treatments. In the present study, we investigated the use of poly(acrylic acid)/TiO2 composite hydrogels both as cleaning agents and protective coatings to shield paper from the detrimental effects of ultraviolet (UV) radiation. To evaluate the efficacy of these treatments, we employed a diagnostic protocol previously developed to differentiate between hydrolytic and oxidative aging processes, based on Raman spectroscopy imaging. Our findings demonstrate that papers coated with poly(acrylic acid)/TiO2 composite hydrogels exhibit enhanced stability and improved resistance to degradation compared to uncoated samples.
Epigenetic Modulation of Estrogen Receptor Signaling in Ovarian Cancer
Authors: Skrzypczak Maciej , Wolinska Ewa , Adaszek Łukasz , Ortmann Olaf , Treeck Oliver
Published: December 2024

Ovarian cancer remains one of the leading causes of cancer-related deaths in women. There are several processes that are described to have a causal relationship in ovarian cancer development, progression, and metastasis formation, that occur both at the genetic and epigenetic level. One of the mechanisms involved in its pathogenesis and progression is estrogen signaling. Estrogen receptors ERα, ERβ and GPER1, in concert with various coregulators and pioneer transcription factors, mediate the effects of estrogens primarily by transcriptional regulation of estrogen responsive genes, thereby exerting pleiotropic effects including regulation of cellular proliferation and apoptosis. The expression and activity of estrogen receptors and their coregulators have been demonstrated to be regulated by epigenetic mechanisms like histone modifications and DNA methylation. Here, we intend to summarize and to provide an update on the current understanding of epigenetic mechanisms regulating estrogen signaling and their role in ovarian cancer. For this purpose, we reviewed publications on this topic listed in the Pubmed database. Finally, we provide an assessment to which extent drugs acting on the epigenetic level might be suitable for therapy of ovarian cancer.
Real-Time Analysis of Industrial Data Using the Unsupervised HDBSCAN Method in Monitoring the Welding Process in a Robotic Cell
Authors: Blachowicz Tomasz , Wylezek Jacek , Sokol Zbigniew , Bondel Marcin
Published: December 2024

The application of modern machine learning methods in industrial conditions is a relatively new challenge and is still in the early stages of development. The currently available computing power of computers makes it possible to process a huge number of production parameters in real time. The article presents, from the practical perspective, the analysis of the manufacturing process associated with welding in a robotic cell using the unsupervised DBSCAN and specifically HDBSCAN machine learning algorithms, while showing its usefulness and advantages from the k-means algorithm. The paper also discusses the problem of predicting and monitoring undesirable situations and proposes the usage of the first derivative of the time-dependent signal of noised data to support the problem solution.
Enhancing Calibration Precision in MIMO Radar with Initial Parameter Optimization
Authors: Kwon Yong Hwi , Kim Chul Ki
Published: December 2024

For Advanced Driver Assistance Systems (ADAS), lots of researchers have been constantly researching various devices that can become the eyes of a vehicle. Currently represented devices are LiDAR, camera, and radar. This paper suggests one of the operation processes to study the radar, which can be used regardless of climate change, weather, day or night. Thus, we propose a simple and easy calibration method for Multi Input Multi Output (MIMO) radar to guarantee performance with the initial calibration parameters. Based on the covariance matrix, the modified signals of all channels improve the performance, reducing unexpected interferences. Therefore, using the proposed coupling matrix, we can reduce the unexpected interference and generate accurately calibrated results. To prove and verify the improvement of our method, the practical experiment is conducted with Frequency Modulated Continuous Wave (FMCW) MIMO radar, mounted on an automotive.
Characteristics of Precipitation, Streamflow, and Sediment Transport of the Hangman Creek in the Pacific Northwest USA: Implication for Agricultural Conservation Practice Implementation
Authors: Yuan Yongping , Kanyuk Sean
Published: December 2024

Anthropogenic climate change and changes to land use and land management practices can have significant impacts on streamflow and sediment transport. In this study, we investigated long-term precipitation, streamflow and suspended sediment load patterns within the Hangman Creek watershed, draining from the Rocky Mountains in Idaho to Washington, to identify the magnitude of changes with the goal of better understanding the links between these processes and the potential effects of agricultural conservation practices (ACPs) implemented since the 1990s. Comparing study periods of 1991 to 2020 with 1961 to 1990, 1991 to 2020 had lower streamflow/precipitation ratios in the highest flow months such as February and March. Most streamflow occurred during winter and spring, so does suspended sediment. In addition, 2018 had much lower suspended sediment load compared to earlier years (1999 and 2000) during high flow seasons (January to May) given that streamflow was higher in 2018 than in 1999 and 2000. These changes may be attributed to adoption of agricultural conservation practices because land cover remained almost unchanged from 2001 to 2021 and ACP adoption increased. Finally, flow frequency analysis showed a strong linkage between higher streamflow events and increased suspended sediment load, with between 81% and 96% of total annual suspended sediment loads transported during the highest 10% of flows.
Compensation of numerical noise at large time steps using temperature fluctuations in an atomistic spin dynamics
Authors: Ivanov Anton Valerievich
Published: December 2024

The atomistic model of classical Heisenberg magnetic material is a system of stochastic differential equations of Landau-Lifshitz with a Langevin source. Strong local exchange interaction leads to the appearance of numerical noise, which significantly limits the time step. Numerical noise manifests itself similarly to temperature fluctuations, which makes it possible to try to compensate for the noise by reducing the temperature. The temperature correction is calculated based on the second equation of correlation magnetodynamics. This approach allows increasing the integration step by almost an order of magnitude, while maintaining the error level at an acceptable level.
A Psychometric Evaluation of Preserving Cultural Heritage as a Form of Psychosocial Support
Authors: Kamiyama Machiko , Sato Masae , Ichijo Reika , Sato Daisuke , Morris John
Published: November 2024

It is now widely recognized that the rescue of local historical materials following a disaster can be an effective tool for the recovery of individuals and communities. After the Great East Japan Earthquake of 2011, a local NPO rescued and restored historical heritage that had been owned by the victims. This study hypothesizes that such activities constitute psychosocial support as recommended by the WHO for survivors. Our informants were people owning damaged historical materials that had been rescued by the NPO. In view of the short-comings of conventional methodology in assessing the merits of psychosocial support, this study applies a psychometric evaluation of how the informants perceived their rescue by the NPO, using a semi-structured interview survey method with a quasi-experimental design. Of the 20 informants, 19 were over 65 years old. Interviews were conducted by clinical psychologists who were not involved in the NPO’s activities so as to ensure an independent evaluation. The results revealed that those who experienced their rescue within three months after the disaster had positive images of the rescue and surrounding events, whereas informants whose rescue was delayed tended to have negative impressions, despite the objective fact that it was the former group who had all suffered greater damage from the disaster. Those informants who succeeded in changing their overwhelmingly negative experiences into positive images also showed a markedly higher rate of engagement with their communities, which can be interpreted as showing higher resilience.
Future Projection of Extremely Heavy Rainfall in the Tohoku District of Japan with Large Ensemble Simulations Using the 5 km Regional Climate Model
Authors: Suzuki Shin-ichi , Morooka Hiroko , Yamazaki Takeshi , Iwasaki Toshiki
Published: November 2024

The Japan Meteorological Agency defines extreme climate events as phenomena occurring once every 30 years or less. To prepare for disasters, we investigated future projections of 30-year return values of heavy precipitation in the Tohoku District of northern Japan based on a large number of ensemble warming projections that are dynamically downscaled to 5-km grids under the Social Implementation Program on Climate Change Adaptation Technology. The 30-year return values of daily and hourly precipitation are projected to significantly increase under global warming, indicating the strengthening of extremely heavy rainfall. Their averaged ratios across the Tohoku District in the 2-K and 4-K warmer climates to those in the present climate are 1.12 and 1.30 times for daily precipitation and 1.18 and 1.45 times for hourly precipitation, respectively. In particular, the 30-year return values are enormous on the eastern slopes of the Kitakami and Abukuma Mountains and the Ou Mountain Range. The rates of increase in the 30-year return values are pronounced in the northern part of Tohoku, where the surface air temperature increase is more significant than in other regions. These results suggest the need to upgrade disaster prevention measures for heavy rainfall as a climate change adaptation in the Tohoku District. We also examined the regional dependency of seasonal variation in the occurrence rates of daily and hourly extreme events. The results indicated that the occurrence rates tend to be relatively high on the Sea of Japan side of the Tohoku District in July due to the Baiu front, over the entire Tohoku District in August due to strong convective instability, and on the Pacific Ocean side due to September typhoons and autumn stationary fronts. This seasonality is projected to remain almost unchanged under warmer conditions.
Contributions of the Large-Scale Earthquake Simulator to Shaking Experiments Over Fifty Years
Authors: Aoki Takashi , Nakazawa Hiroshi , Kawamata Yohsuke , Kajiwara Koichi
Published: November 2024

The Large-scale Earthquake Simulator at the National Research Institute for Earth Science and Disaster Resilience was established in 1970 as the first facility in Tsukuba Science City and remained in operation until 2022. Over its more than 50 years of operation, the facility conducted a total of 447 experiments, playing a vital role in advancing seismic engineering. This article summarizes the contributions of the now-decommissioned facility by outlining its updates over time and providing examples of the experiments conducted to adapt to evolving needs.
Voces de madres juarenses: la experiencia de maternar a un hijo o hija con discapacidad
Authors: Vargas Alba Alejandra , Cervantes Herrera Ana del Refugio , Plascencia González Martín
Published: December 2024

Mothers of sons and daughters with disabilities usually invest time, money, physical and mental energy, in addition to managing care and attention to basic needs. Although these activities are usually vital, mothers are often not recognized as people who also need care, leading them to live alone, facing impacts and challenges in various areas of their lives. Through qualitative research, sought to know: what and how have the experiences of mothering a son or daughter with some type of disability, physical limitation, condition or mental problem been in Ciudad Juárez? For this, three open interviews were carried out, the information obtained was analyzed from the thematic analysis approach. The results are presented in 5 categories to show the voices of mothers of sons and daughters with disabilities about: 1) the beginning of the experience of mothering in front medical violence, 2) loneliness, isolation and their impacts on mothers, 3) emotions and family dynamics in front of disability, 4) mothering in the presence and absence of support networks and 5) guides and care criteria proposed by and for mothers of sons and daughters with disabilities. It is concluded that loneliness and isolation are main factors for experiencing impacts and effects in various areas of life of mothers, while providing information, awareness and support on disability and mothering are care guides in the voices of mothers.
ANALISIS LOYALITAS KERJA KARYAWAN DI UNP HOTEL & CONVENTION CENTER PADANG
Authors: Aldhinata Biaggi , Waryono
Published: November 2024

Penelitian ini dilatarbelakangi karena terdapat permasalahan yang terjadi mengenai loyalitas para karyawan di UNP Hotel & Convention Center Padang. Tujuan penelitian ini adalah menganalisis loyalitas karyawan di UNP Hotel & Convention Center Padang yang ditinjau dari indikator: 1) Ketaatan atau kepatuhan, 2) Bertanggung jawab, 3) Pengabdian, dan 4) Kejujuran. Penelitian ini bersifat deskriptif dengan data kualitatif yang diperoleh melalui teknik observasi, wawancara, dan dokumentasi, dengan informan penelitian dipilih menggunakan teknik purposive sampling dan snowball sampling. Setelah itu, data dianalisis melalui reduksi data, penyajian data, pengambilan kesimpulan dan verifikasi.
Secara keseluruhan, hasil penelitian menunjukkan bahwa analisis loyalitas kerja karyawan UNP Hotel & Convention Center Padang ditinjau dari indikator: 1) Ketaatan atau kepatuhan, hasil penelitian menunjukkan bahwa sebagian karyawan belum sepenuhnya mematuhi peraturan yang berlaku, seperti ketepatan waktu dan penggunaan seragam yang sesuai. 2) Bertanggung jawab, para karyawan telah menunjukkan sikap tanggung jawab dengan melaksanakan job desk sesuai instruksi dan melakukan overhandle kepada karyawan shift berikutnya. 3) Pengabdian, karyawan menunjukkan pengabdian dengan siap melakukan overtime dan bekerja pada hari libur demi kepentingan hotel. 4) Kejujuran, karyawan UNP Hotel & Convention Center Padang menunjukkan kejujuran dalam pekerjaan mereka, baik dalam berkomunikasi maupun dalam menjaga kualitas produk dan layanan.
Kata kunci: Hotel, Karyawan hotel, Loyalitas karyawan
Bir Osmanlı Paşasının Kitap Dünyası: Silahdar İbrahim Paşa ve Kütüphanesi
Authors: Demir Selçuk
Published: November 2024

Osmanlı Devleti’nde XVIII. yüzyılın başlarından itibaren kitaba olan ilgi artmış ve kitapseverlerin sayısında büyük bir artış meydana gelmiştir. Başta dönemin padişahları olmak üzere pek çok devlet adamı zengin kitap koleksiyonları oluşturmuştur. Kitap meraklısı devlet adamlarından biri de Silahdar İbrahim Paşa’dır. Silahdar İbrahim Paşa Enderun’da yetişmiş, Erzurum, Haleb ve Diyarbekir gibi eyaletlerde beylerbeylik yapmıştır. Gerek eğitim hayatında ve gerekse meslekî hayatında kitap temin etmekten geri kalmamış, ciddi bir kitap koleksiyonu oluşturmuştur. Bu makalenin amacı XVIII. yüzyıl Osmanlı dünyasında okuma kültürü üzerine yapılan çalışmalara katkıda bulunmaktır. Bunun için ömrünün önemli bölümünü İstanbul’dan uzak vilayetlerde geçiren Silahdar İbrahim Paşa tercih edilmiştir. O’nun üzerinden taşrada görev yapan bir Osmanlı devlet adamının kitapları incelenmiştir. Silahdar İbrahim Paşa’nın en çok hangi tür kitaplara sahip olduğu, en fazla hangi yazarları okuduğu, kitap seçiminde etkili olan faktörlerin neler olduğu sorularına cevap aranmıştır. Kaynak olarak MAD.d 665 numaralı muhallefat defterinden istifade edilmiştir. Defterde yer alan bilgiler ışığında Silahdar İbrahim Paşa’nın kitapları tasnif edilmiş, ayrıca önemli kitaplar hakkında bazı bilgiler verilmiştir.
Features of the organization of medical care in private medical organizations of a dermatological profile.
Authors:   Federal State Budgetary Educational Institution of Higher Education «St. Petersburg State Pediatric Medical University» of the Ministry of Health of the Russian Federation, Karailanov M. G. ,   Federal State Budgetary Military Educational Institution of Higher Education “Military Medical Academy named after S. M. Kirov» of the Ministry of Defense of the Russian Federation, Vasilchenko P. S. ,   Federal State Budgetary Educational Institution of Higher Education «St. Petersburg State Pediatric Medical University» of the Ministry of Health of the Russian Federation, Sushkova N. S. ,   Federal State Budgetary Educational Institution of Higher Education “Voronezh State University”
Published: December 2024

The population’s need for dermatological care requires the creation of a new level of organization of medical care based on medical information systems capable of improving the activities of private medical organizations and improving the quality of services provided in the dermatological profile.
Purpose of the study is to reveal the features and directions of the formation of high–quality dermatological care in private medical organizations.
Materials and methods. In the process of achieving this goal, statistical data, legislation, and the medical information system were
studied. Methods of observation, generalization, comparison, grouping, and data analysis were used.
Subject. An algorithm for organizing dermatological medical care, focused on improving quality through the introduction of a narrowly specialized medical information system.
Results. The basic algorithms for the implementation of a medical information system for a private clinic of a dermatological profile based on the construction of a scheme of medical and social characteristics of dermatological diseases and focused on nosological forms of the most common etiologies are proposed. A distinctive feature of the organization of the provision of medical services by private dermatological clinics is the quality, which allows not only to provide a highly effective service to the population, but also to gain a competitive advantage in the market. In the process of development and implementation, the basic principles of an information system
focused on achieving the set goals were determined. The version of the medical information system implemented in practice, based on the research materials, made it possible to integrate.
Conclusion. The specific features of the implementation of a narrowly specialized medical information system in private medical organizations are determined. Directions of improvement have been formed within the framework of the state implementation of a common electronic database of patients through EGISZ.
AUGMENTING ISLAMIC DIGITAL PAYMENT EFFECT ON MUSLIM CUSTOMER PURCHASE DECISION ON MICRO, SMALL AND MEDIUM ENTERPRISES’ (MSMEs) PRODUCTS
Authors: Riofita Hendra
Published: November 2024

To support the role of digital transaction in improving the growth of economy, the effect of Islamic digital payments on Muslim customer purchase decision on Micro, Small and Medium Enterprises’ (MSMEs) products should be augmented. This study employs a modified Technology acceptance Model (TAM) to examine whether  perceived values mediate or augment the effect of Islamic digital payments on purchase decisions of MSMEs’ products. Using data gathered from 477 respondents,  we find that the perceived values do augment Islamic digital payment effect on Muslim customer purchase decision on MSMEs products. However, their augmentation for the case of cash payments is absent. In other words, Islamic digital payments and perceived values are together the predictors of Muslim customer purchase decision while cash payments are not.  We also note that the Islamic digital payments are the predictor of perceived values.
FINANCIAL RESILIENCE AMONG WOMEN SMALL AND MEDIUM ENTERPRISE IN MALAYSIA DURING AND AFTER COVID-19: THE ROLE OF ISLAMIC SOCIAL FINANCE
Authors: Yusuf Muhammad-Bashir Owolabi , Mahadi Nur Farhah , Kassim Salina , Mohd Yusoff Syarah Syahira Binti
Published: November 2024

The COVID-19 pandemic disproportionately impacted women-owned small and medium enterprises (SMEs) in Malaysia, exposing their vulnerabilities and highlighting the need for effective resilience strategies. This study examines the role of Islamic social finance in enhancing the financial resilience of these businesses during and beyond the pandemic. To achieve this goal, the study explores three key areas i.e., identifying factors shaping the financial resilience of women-owned SMEs in Malaysia during and beyond the pandemic, assessing the effectiveness of Islamic social finance instruments in fostering financial resilience for these businesses, and formulating recommendations for effective policies that strengthen the financial resilience of women-owned SMEs, enabling them to navigate future pandemics more effectively. Using a Partial Least Squares Structural Equation Modeling (PLS-SEM) approach, we document no significant effects of Islamic social finance instruments on the financial resilience of women-owned SMEs.  We argue that this documented insignificance could be due to the ways Islamic Social Finance (ISF) is operationalized. At the same time, contradicting previous research on the ISF women-owned SMEs financial resilience, we also believe that further investigation is needed.
THE LEVEL OF CONVERGENCE TO SHARI’AH PRINCIPLES AND CORPORATE PROFITABILITY
Authors: Parlak Deniz , Yildiz Mehmet Emin , Yılmaz Naci
Published: November 2024

This study constructs a Shari'ah convergence index for 1,362 companies operating in 10 different Islamic countries between 2017 and 2021 and assesses its relation to corporate profitability. Shari’ah screening variables are based on existing Shari’ah screening literature and applications, and variable weights are assigned using the Integrated Determination of Objective Criteria Weights (IDOCRIW) technique, a widely used, multi-criteria decision-making method. The results suggest that 4% of the sample is completely non-compliant as they engage in non-permissible business activities, 82% has a non-compliant activity level below 30% and the remaining 14% has a non-compliant activity level between 41 and 99%. Our panel data regression analysis shows that, while the Shari'ah convergence index does not affect operating profitability, it does have a statistically positive effect on total corporate profitability. These findings are attributable to two factors, interest burden and debt level. It seems that, for Islamic companies, The high cost of debt service may offset the advantage of high leverage on profitability.
Performance Comparison of Gradient-Free Optimization Methods for Well Placement and Well Controls Optimization for Geologic CO2 Storage
Authors: Tom Imaobong , Nguyen Quang Minh , Onur Mustafa
Published: December 2024

In this study, we investigate the use of three different gradient-free population-based optimization methods—namely, iterative Latin hypercube sampling (ILHS), particle swarm optimization (PSO), and genetic algorithm (GA)—for the well placement and well controls optimization problem of CO2 underground storage in a 2D saline aquifer with bound constraints on the design variables. We also consider both simultaneous and sequential optimizations of well locations and well controls using these gradient-free methods. The optimization problem involves finding the optimal well types, well locations, or well controls for a CO2 injection problem in a synthetic saline aquifer compositional model built in a commercial simulator. The objective function formulated for the CO2 injection problem is the net present environmental value (NPEV) involving discrete design variables (well types and well locations) and continuous design variables (well controls). We observe that for simple well-location optimization problems involving one or two wells, all three algorithms obtained comparable results, given the same number of samples and number of iterations. However, for more complex cases such as the sequential or simultaneous optimization problems, when multiple wells that may include injectors and producers are present, we observe significant differences in the selection of the optimal well types and well locations among the three optimizers. In the simultaneous optimization of well types, well locations, and well controls, when both injectors and producers are bottomhole pressure (BHP) controlled, the results show that it is more optimal for at least one producer to be present, and for the injectors to be operated at the upper bound of the injector BHP, while the producers are operated at the lower bound of the producer BHP to maximize the NPEV.
What is a Correct Resistance Pre- and Post-Flashing: Application of EQUALIZER DART
Authors: Llanos Marco Melo , Irani Mazda
Published: December 2024

Flow Control Devices (FCDs) have emerged as promising tools for enhancing recovery in Steam Assisted Gravity Drainage (SAGD) production wells. Initially, it was hypothesized that FCDs delayed steam breakthrough by homogenizing injection and production, equalizing flow, and compensating for pressure changes along the wellbore. However, recent advancements in Inflow Control Devices (ICDs) featuring internal flashing have shown potential for superior performance. Internal flashing, characterized by self-boiling of water due to pressure reduction, has become a focal point in ICD design, with the prevailing belief in the SAGD industry that increased flashing enhances performance, leading many vendors to extend the flashing zone. Contrary to common belief, excessive choking can impede flow rates without necessarily improving performance. This paper introduces the concept of sandface subcool, defined as the subcool at the sandface calculated based on temperature and pressure. When sandface subcool reaches zero, conditions are conducive to steaming, potentially leading to severe steam coning. The role of ICDs is to elevate upstream pressure, increasing sandface subcool and halting steam flashing at the sandface. However, excessive choking can hinder flow rates, rendering it unnecessary to raise sandface subcool above zero degrees.

Furthermore, the heterogeneity of Athabasca McMurray oil sands reservoirs significantly impacts SAGD recovery outcomes. In response, the implementation of ICDs has become pivotal in enhancing SAGD performance. This study delves into the variation of permeability and temperature along the wellbore, emphasizing the importance of resistance before and after flashing in understanding producer performance. Through comparative analysis of ICD systems with varying resistance profiles, this study identifies optimal resistance parameters for different geological structures.

This study introduces a novel model designed to accurately simulate flashing under thermal conditions, demonstrating its efficacy by matching C-FER (Continuous Flow Extraction Rate) data. Subsequently, this model is integrated into a comprehensive wellbore model to replicate well performance pre- and post-flashing. Specifically, the performance of EQUALIZER Dart, featuring various resistance profiles, is modeled and contrasted with previously deployed EQUALIZER Select wells. The findings reveal that EQUALIZER Dart can enhance oil production rates by 40% and reduce steam consumption by 20% compared to baseline scenarios, highlighting its potential for optimizing SAGD operations.
Research on support technology of driving roadway under the influence of continuous fault fracture zone
Authors: Zhang Li Xin , Li Yi , Li Gang
Published: December 2024

In order to study the support technology of roadway excavation under the influence of multiple fault fracture zones, this paper takes 2101 transport trough of Donggou Coal Mine as the engineering background, and analyzes the surrounding rock variation rules at different stages during roadway excavation under the influence of multiple fault fracture zones through numerical simulation software. The results show that the main factors affecting the surrounding rock are vertical stress and unstable rock mass in the fracture zone. Through numerical simulation, the plastic zone is reduced by 58% after grouting and strengthening support, and the deformation of roof, bottom plate and two sides is reduced by 3.05m, 0.5m and 1.6m respectively. Due to the change of rock stratum caused by fault drop after breaking zone, it is necessary to strengthen the support of roadway roof. After supporting, the plastic zone is reduced by 40%, and the deformation of roof and two sides is reduced by 0.75m. The results of simulation analysis meet the requirements of support and provide a theoretical basis for mine construction. It also provides reference for the excavation of roadway under similar conditions.
1H NMR-based Metabonomic Analysis of Serum and Flap Tissue of Gensenoside Rb1 on Survival of Random-Pattern Skin Flap in Rats
Authors: Huang Yeqian , Liu Yu , Meng Fanjun , Wijaya Wilson Adrian , Cao Chang
Published: December 2024

The randomly patterned skin flap is limited by the length-to-width ratio, which can affect its clinical application. This study aims to review the effect of ginsenoside Rb1 on the survival of random skin flaps and analyze the mechanism by metabonomic approaches. Sprague-Dawley rats were divided into a control group, an ischemia-reperfusion (I/R) group, and a ginsenoside Rb1 group. Serum and middle flap tissue of the rats were collected for 1H-NMR spectroscopy detection and computer pattern recognition analysis. Ten days post-surgery, the survival rate of the dorsal flaps in the Rb1 group (61.06 ± 3.71) % was significantly higher than in the I/R group (50.46 ± 1.41) %. In 24 hours after surgery, the 1H-NMR spectrum analyses demonstrated increased lipid content in the serum in I/R group. Compared with the serum in I/R group, the Rb1 group showed significantly higher levels of glutamate creatine fumarate, while lactate choline/phosphocholine N-acetylglycoprotein allantoin was decreased. The contents of ATP/ADP/AMP of glutamine, citrate, tauric acid, and fumarate in flap tissue were increased while that of lactate acetate acetoacetate was significantly decreased. Our finding suggests that ginsenoside Rb1 may have the potential to enhance the survival rate of dorsal random flaps and provide protective effects.
Additive impact of cardiovascular diseases and hearing loss on all-cause and cardiovascular mortality: A longitudinal nationwide population-based study
Authors: Li Ling , Li Lan , Qin Chenchen , Zhong Qian
Published: December 2024

Background
Cardiovascular diseases (CVD) and hearing loss (HL) are significant public health concerns, sharing common pathological mechanisms and being associated with severe health outcomes. This study investigates the impact of CVD and HL on all-cause and cardiovascular mortality.
Methods
Data from the National Health and Nutrition Examination Survey (NHANES) between 1999 and 2018 were analyzed, along with mortality data from the National Death Index (NDI) up to December 2019. Initially, we explored the correlation between different types of HL and CVD. Participants were categorized into four groups based on the presence of CVD and HL, and mortality outcomes were analyzed accordingly.
Results
Among 10,614 participants, 6,039 (56.9%) had neither CVD nor HL (CVD-/HL-), 3,465 (32.6%) had HL only (CVD-/HL+), 279 (2.6%) had CVD only (CVD+/HL-), and 831 (7.8%) had both CVD and HL (CVD+/HL+). Compared to individuals without HL, those with overall frequency HL (OR = 1.49, 95% CI: 1.14–1.96, p = 0.004) and high-frequency HL (OR = 1.41, 95% CI: 1.04–1.90, p = 0.03) showed a positive correlation with CVD, while low-frequency HL (OR = 1.04, 95% CI: 0.86–1.26, p = 0.71) showed no significant association. In terms of mortality, compared to the CVD-/HL- group, the CVD+/HL- group (HR = 1.88, 95% CI: 1.29–2.73, p = 0.001) and the CVD+/HL + group (HR = 2.19, 95% CI: 1.69–2.83, p < 0.0001) had increased all-cause mortality risks, whereas the CVD-/HL + group did not show statistical significance (HR = 1.24, 95% CI: 0.98–1.57, p = 0.07). The CVD+/HL- group (HR = 3.66, 95% CI: 2.00–6.71, p < 0.0001) and the CVD+/HL + group (HR = 2.91, 95% CI: 1.89–4.47, p < 0.0001) had increased cardiovascular mortality risks, while the CVD-/HL + group did not show statistical significance (HR = 1.24, 95% CI: 0.98–1.57, p = 0.07).
Conclusion
The simultaneous presence of CVD and HL significantly raised the likelihood of death from any cause and cardiovascular events. Patients with either condition may need more vigilant treatment to avoid the onset of the other condition and lower the risk of death.