bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of ThyroSeq v2 performance in thyroid nodules with indeterminate cytology
Authors: Valderrabano Pablo , Khazai Laila , Leon Marino E , Thompson Zachary J , Ma Zhenjun , Chung Christine H , Hallanger-Johnson Julie E , Otto Kristen J , Rogers Kara D , Centeno Barbara A , McIver Bryan
Published: January 2017

ThyroSeq v2 claims high positive (PPV) and negative (NPV) predictive values in a wide range of pretest risks of malignancy in indeterminate thyroid nodules (ITNs) (categories B-III and B-IV of the Bethesda system). We evaluated ThyroSeq v2 performance in a cohort of patients with ITNs seen at our Academic Cancer Center from September 2014 to April 2016, in light of the new diagnostic criteria for non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). Our study included 182 patients (76% female) with 190 ITNs consecutively tested with ThyroSeq v2. Patient treatment followed our institutional thyroid nodule clinical pathway. Histologies of nodules with follicular variant papillary thyroid carcinoma or NIFTP diagnoses were reviewed, with reviewers blinded to molecular results. ThyroSeq v2 performance was calculated in nodules with histological confirmation. We identified a mutation in 24% (n = 45) of the nodules. Mutations in RAS were the most prevalent (n = 21), but the positive predictive value of this mutation was much lower (31%) than that in prior reports. In 102 resected ITNs, ThyroSeq v2 performance was as follows: sensitivity 70% (46–88), specificity 77% (66–85), PPV 42% (25–61) and NPV 91% (82–97). The performance in B-IV nodules was significantly better than that in B-III nodules (area under the curve 0.84 vs 0.57, respectively; P = 0.03), where it was uninformative. Further studies evaluating ThyroSeq v2 performance are needed, particularly in B-III.
Mecanismos sancionatorios alternativos al proceso penal. Una visión desde el Derecho inglés.
Authors: Salat Paisal Marc
Published: January 2017

Durante el 2015, el legislador español aprobó dos reformas legislativas a través de las que ha abierto todavía más la posibilidad de plantearse la creación de mecanismos alternativos al proceso penal. En el presente trabajo, partiendo de la base de la eliminación de las faltas penales y de la creación de un nuevo proceso penal monitorio, se analizan las alternativas al proceso penal existentes en el derecho comparado y, en particular, en el ordenamiento jurídico inglés. Con ello, se pondrá de manifiesto las distintas alternativas existentes en otros países europeos así como los distintos problemas que ha planteado su aplicación. Finalmente, se propone un borrador de propuesta para la creación de un mecanismo alternativo al proceso penal en el derecho español aplicable frente a delincuentes primarios y siempre que se cometan delitos leves o menos graves.
BRANDUOLINIO GINKLO NENAUDOJIMO NORMA IR ATGRASYMAS: KONCEPCIJŲ SĄVEIKA JAV ATVEJU
Authors: Bladaitė Neringa
Published: January 2017

Straipsnyje nagrinėjamos branduolinio ginklo nenaudojimo normos ir branduolinio atgrasymo strategijos (ne)suderinamumo galimybės. Siekiant išgryninti teorinius koncepcijų sąveikos variantus, pirmojoje straipsnio daly­je atliekama teorinė konstruktyvistinės normų bei realistinei srovei priskiria­mos atgrasymo teorijos analizė. Išskiriant galimo koncepcijų suderinamumo ir ryškiausios priešpriešos taškus, konstruojamas tam tikras teorinis rėmas empirinei JAV atvejo analizei, kuri pateikiama antrojoje straipsnio dalyje. Tyrimas, grindžiamas kokybine turinio analize, atskleidė, kad nagrinėjamu 2009–2015 metų laikotarpiu JAV branduolinio ginklo nenaudojimo norma dėl dinamikos įgijo tradicijos formą. Ši normos forma palieka nedidelę bran­duolinio ginklo panaudojimo galimybę, kuri yra būtina atgrasymui. Taip bent teoriškai išsprendžiamas koncepcijų suderinamumo klausimas. Tačiau dėl tokio nenatūralaus nenaudojimo normos ir atgrasymo derinimo labiausiai nukenčia atgrasymo patikimumo elementas, o tai JAV branduolinę laikyseną paverčia neaiškia ir ateityje gali kelti tam tikrą grėsmę.
V. PUTINO VALDŽIOS VEIKIMAS: KELIŲ SLUOKSNIŲ ELITO GRUPIŲ SISTEMA
Authors: Keršanskas Vytautas
Published: January 2017

Straipsnyje teigiama, kad esminį vaidmenį Rusijos politinėje sistemoje vaidina įvairios galios elito grupės, o jų ir Vladimiro Putino, kaip sistemos arbitro, analizė padeda geriausiai suprasti sistemos veikimo bruožus. Pir­miausia darbe apžvelgtos pokomunistinės Rusijos politinio elito susidarymo aplinkybės, nurodyti pagrindiniai jį lėmę veiksniai ir pateiktos Rusijos ga­lios elito, ypač valdant V. Putinui, veikimo prielaidos. Remiantis pasiūlytu Rusijos politinės sistemos aiškinimu ir elito grupių skirstymo modeliu, bus pateikta pagrindinių veikėjų – sisteminių ir nesisteminių, formalių ir ne­formalių – apžvalga. Sisteminiai veikėjai apima tiek artimiausią V. Putino aplinką, tiek opoziciją imituojančius veikėjus. Nesisteminių veikėjų analizę papildo ir jų eliminavimo iš sistemos metodų aprašymas. Teigiama, kad, nors Rusijos politinė sistema yra sunkiai atidaroma „juodoji dėžė“, elito grupių sąveika ir konkurencija leidžia daryti išvadas apie pačioje sistemoje vyks­tančius pokyčius.
Permeation of limonene through disposable nitrile gloves using a dextrous robot hand
Authors: Banaee Sean , Hee Shane S Que
Published: January 2017

Objectives

The purpose of this study was to investigate the permeation of the low-volatile solvent limonene through different disposable, unlined, unsupported, nitrile exam whole gloves (blue, purple, sterling, and lavender, from Kimberly-Clark).

Methods

This study utilized a moving and static dextrous robot hand as part of a novel dynamic permeation system that allowed sampling at specific times. Quantitation of limonene in samples was based on capillary gas chromatographymass spectrometry and the internal standard method (4-bromophenol) .

Results

The average post-permeation thicknesses (before reconditioning) for all gloves for both the moving and static hand were more than 10% of the pre-permeation ones (P≤0.05), although this was not so on reconditioning. The standardized breakthrough times and steady-state permeation periods were similar for the blue, purple, and sterling gloves. Both methods had similar sensitivity. The lavender glove showed a higher permeation rate (0.490±0.031 µ/cm2/min) for the moving robotic hand compared to the non-moving hand (P≤0.05), this being ascribed to a thickness threshold.

Conclusions

Permeation parameters for the static and dynamic robot hand models indicate that both methods have similar sensitivity in detecting the analyte during permeation and the blue, purple, and sterling gloves behave similarly during the permeation process whether moving or non-moving.
Variaciones microclimáticas en el interior y exterior del bosque de caldén (Prosopis caldenia), Argentina
Authors: Duval Valeria Soledad , Campo Alicia María
Published: January 2017

Clima y vegetación son variables del espacio físico que poseen una relación dinámica y de interdependencia. La flora modifica los elementos climáticos y da lugar a un microclima cuya caracterización está en función de las condiciones climáticas regionales y de la estructura de la vegetación. El objetivo del trabajo fue comparar las variaciones climáticas (interior y exterior) del bosque de caldén en la Reserva Provincial Parque Luro. Se analizaron y compararon estadísticamente los datos de temperatura, humedad relativa, velocidad, dirección del viento y precipitación de dos estaciones meteorológicas para el 2012. Se demostró la influencia del bosque en los parámetros climáticos y se comprobó que las variaciones mayores se dieron en la velocidad del viento, la temperatura diaria y las precipitaciones.
La determinación de potencialidades agropecuarias y silvícolas en zonas de montaña: municipio Tercer Frente, Cuba
Authors: Ramón Puebla Adonis , Martínez Quintana Leusnier , Suárez García Célida , Salinas Chávez Eduardo
Published: January 2017

La entrega en usufructo de tierras ociosas para la producción de alimentos en el municipio Tercer Frente no siempre considera las potencialidades reales del territorio, ni las regulaciones y normas ambientales vigentes para la ocupación de dichos espacios. Esta investigación parte de la obtención de mapas de cobertura vegetal, la modelación en sig de las variables y el análisis de las normas ambientales vigentes para cada uso propuesto. Se ofrece un escenario de potenciales agropecuarios y silvícolas para su adecuado aprovechamiento en función de la producción de alimentos del municipio, y se determina que el territorio, a pesar de ser montañoso en un 95%, cuenta con lugares adecuados para este desarrollo sin comprometer la protección del medio ambiente.
Geomorfología de la duna remontante ubicada en el acantilado sur del Castillo de Araya, estado Sucre (Venezuela)
Authors: Núñez Ravelo Franklin , Hernández Labrador Michel , Ugas Pérez María
Published: January 2017

El objetivo es caracterizar en lo físico-químico y morfodinámico la duna remontante ubicada en Araya, para ello se asumieron las siguientes fases de investigación: a) “Campo”, que permitió la colecta sedimentológica en el ápice y la base del depósito; b) “Laboratorio” a fin de determinar tamaño y forma de los granos, contenido de CaCo y minerales pesados, y c) “Oficina”, centrada en el análisis estadístico. Se trata de arenas finas, generalmente redondeadas, bien seleccionadas, mineralógicamente compuestas por: 63,68% de cuarzo + feldespatos, 33,75% CaCo3 y 2,56% de minerales pesados, las cuales experimentan un cabalgamiento promedio de 1,16 metros sobre el acantilado entre septiembre-abril, posiblemente vinculado al incremento de la velocidad de los vientos locales, los cuales registran en promedio hasta 81,04 m/s.
Aguas turbias: los nuevos cuerpos de agua de las urbanizaciones cerradas de Buenos Aires (Argentina)
Authors: Ríos Diego Martín
Published: January 2017

Últimamente, los cuerpos de agua se han convertido en uno de los rasgos paisajísticos más valorados por el urbanismo neoliberal en distintos lugares del mundo. La apropiación y producción de condiciones acuáticas aprovechadas por los desarrollos inmobiliarios y turísticos más exclusivos, así como también la generación de contradicciones ambientales desiguales, son dos caras de un mismo proceso que crece notablemente. En este trabajo se aborda el caso de los cuerpos de agua de las urbanizaciones cerradas en las áreas inundables de Tigre, al norte de Buenos Aires. A partir de información primaria y secundaria, se analizan las formas en que se producen, las consecuencias ambientales adversas y las respuestas diferenciales que se generan tanto “puertas adentro” como “puertas a fuera” de esos emprendimientos suburbanos.
Espaços públicos e mobilidade urbana: uma análise comparada dos arranjos normativos de Bogotá (Colômbia) e do Rio de Janeiro (Brasil)
Authors: Ardila Pinto Ana Marcela , Parente Ribeiro Leticia
Published: January 2017

En el campo de los estudios urbanos, la dicotomía entre espacios públicos y de circulación es bastante hegemónica. Recientemente, los debates académicos y políticos alrededor del concepto de movilidad han desafiado esta visión. Se observa un diálogo creciente entre la gestión de los desplazamientos y el fortalecimiento de los espacios públicos, en relación con aspectos morfológicos, políticos y de convivencia en las ciudades. El análisis comparativo de las políticas de movilidad de Bogotá y de Río de Janeiro, desde 1990, evidencia un aumento significativo de la importancia de los espacios públicos, así como también diferencias locales sobre su papel en la planeación del transporte y del crecimiento urbano, en el reconocimiento de nuevas formas de movilidad y en la regulación de la convivencia entre los ciudadanos.
The Homicide Atlas in Colombia: Contagion and Under-Registration for Small Areas
Authors: Urdinola B. Piedad , Torres Áviles† Francisco , Velasco Jairo Alexander
Published: January 2017

El atlas del homicidio en Colombia es una representación visual de la expansión y agravamiento del conflicto armado interno en las décadas más mortales: 1990 a 2009. Sin embargo, el subregistro de la mortalidad sigue siendo un problema en la mayoría de los países en desarrollo, más notablemente en el estudio de causas específicas de muerte en áreas pequeñas. Este documento propone un Método Espacial Bayesiano para identificar el subregistro de la mortalidad en los municipios. Los mapas de probabilidad ayudan a identificar los municipios subregistrados en Colombia que coinciden con el aumento de la violencia a principios del siglo XXI, no capturada en sistemas del registro vitales. También muestra que las mujeres sufren mayores problemas de subregistro que los hombres. Los atlas del homicidio corregidos facilitan la interpretación y la metodología propuesta demuestra ser una buena fuente de identificación del subregistro en poblaciones pequeñas.
Las respuestas de los habitantes al proyecto Ciudades Rurales Sustentables en Chiapas (México)
Authors: Ruiz López Cinthia Fabiola
Published: January 2017

En el 2007, el Gobierno del estado de Chiapas, México, instaló el proyecto Ciudades Rurales Sustentables que proponía el reacomodo de población de Ostuacán y Santiago El Pinar en centros con infraestructura, servicios básicos y vivienda. No obstante, los habitantes respondieron de manera diferencial al programa. El presente artículo se centra en analizar las formas de actuar de los pobladores y los factores que justifican ese comportamiento. El análisis se basa en la vida cotidiana, entendida como la construcción social de un territorio, para lo cual se retomó información de entrevistas, observaciones de sitio y análisis documental. Se muestra la relación directa entre las respuestas a una propuesta gubernamental y las prácticas cotidianas delos habitantes de un territorio.
Configuración espacial de la formación urbana regional del Eje Cafetero colombiano
Authors: Ríos Mario Gaviria
Published: January 2017

El objetivo de este trabajo es caracterizar la configuración de la formación espacial urbano-regional del Eje Cafetero (Colombia) y valorar su condición de sistema urbano de carácter policéntrico. Para ello se recurre a un enfoque morfológico asociado a la distribución de las masas de población sobre el territorio, con el cual se identifican centros y subcentros en el sistema de ciudades que integran la formación espacial. El ejercicio se complementa con un análisis de jerarquía y condiciones de desigualdad de peso y dimensión entre las ciudades, para lo cual se estiman índices a partir de los principios de “rango-tamaño” y primacía urbana. Las evidencias aportadas permiten definir este sistema urbano como una ciudad región con estructura policéntrica.
México cartográfico: una historia de límites fijos y paisajes fugitivos
Authors: Arango López Cindia
Published: January 2017

“Esta no es una historia de mapas ni de paisajes. Es una historia de seres humanos”. Estas son las palabras con las que el historiador Raymond B. Craib presenta su libro: México cartográfico: una historia de límites fijos y paisajes fugitivos. Profesor de la Universidad de Cornell y Doctor en Historia por la Universidad de Yale (Estados Unidos), este autor brinda un significativo aporte a la interpretación y usos de la cartografía en el análisis histórico y político en la formación del Estado mexicano.
Clinical validation study of the SignCare Vital Signs Monitor of Fundación Cardiovascular de Colombia
Authors: Rodríguez-Salazar Leonardo Andrés , Gamboa-Delgado Edna Magaly , Plata Rangel Sherneyko , Mantilla-Prada Oscar Alberto , Sarmiento-Caraballo Eugenio , Rincón-Riveros José Domingo
Published: January 2017

Introduction: In Colombia, due to the difficult access to health services and to geographic conditions, the implementation and innovation of telemedicine technological tools is a priority. Having a validated vital signs monitor (VSM) improves proper medical treatment and diagnosis.Objective: To design and perform clinical trials for the SignCare VSM.Materials and methods: A device for continuous monitoring of electrocardiography, respiration, oxygen saturation, temperature and noninvasive blood pressure (NIBP) was designed. This device was validated in a laboratory in order to ensure a robust prototype, close to the level of commercial medical devices. Clinical trials were performed through a cross-section study with 98 patients, whose vital signs were measured using the SignCare monitor and a commercial monitor. These two measurements were compared using Pearson’s correlation coefficients.Results: There were no statistically significant differences between the results obtained with the SignCare VSM and the commercial monitor. The highest correlations were found for the following items: heart rate by electrocardiogram (r=0.844), heart rate by oxymetry (r=0.821), body temperature (r=0.895), systolic blood pressure (r=0.780), and diastolic blood pressure (r=0.811).Conclusions: The SignCare device is as reliable as the commercial monitor in the qualitative detection of morphologic alterations of electrocardiogram records, as well as in breathing, temperature, oxygen saturation and blood pressure parameters, which makes it recommendable for clinical use in adult population.
Fulminant gas gangrene in an adolescent with immunodeficiency. Case report and literature review
Authors: García Edna Karina , Sierra Pedro Alberto , Quintero-Guevara Omar , Jaramillo Lina
Published: January 2017

Immunity defects are important predisposing factors to aggressive infections with high risk of mortality. The case of a teenager with a history of immunodeficiency, who developed gas gangrene infection originated in the left lower limb is reported here. The disease progressed in less than 24 hours, developed systemic involvement and led to multiple organ failure and death. Pathophysiological aspects and features of the agent are reviewed here, highlighting the importance of high index of clinical suspicion and immediate handling.
Secondary erythrocytosis due to hypoxemia as prognosis in exacerbated chronic pulmonary diseases
Authors: Galindo Javier Leonardo , Granados Carlos Eduardo , Galeano Adriana Catalina , Callejas Ana Milena , Sánchez Víctor Leonardo
Published: January 2017

Introduction: Even though exacerbations are the main cause of emergency consultation in patients suffering from lung diseases, erythrocyte parameters are not assessed in their prognosis. Thus, determining the implications of erythrocyte parameters might contribute to define the usefulness of phlebotomy or red blood cells transfusion in these patients.Objective: To establish a possible relationship between the different hematocrit levels with a 30-day prognosis in patients admitted with exacerbated chronic lung disease and hypoxemia.Materials and methods: A study based on a 30-day follow-up was conducted. Variables were described using an additional categorization by hematocrit levels and an adjustment in a multivariate model through logistic regression.Results: Follow-up was completed for 110 Patients. The frequency of anemia was 7.3% and of erythrocytosis, 14.5%. A significant association to the outcome using Anthonisen score (OR=10.45, 95%CI: 1.11-98.48, p=0.04), hypertension (OR=11.02, 95%CI: 1.32-91.75, p=0.026) and heart failure (OR=0.09, 95%CI: 0.01-0.82, p=0.032) was found.Conclusion: This research could not determine any relationship between erythrocyte parameters and prognosis of patients suffering from pulmonary diseases; nevertheless, extreme values of hematocrits tended to have adverse outcomes.
Bilateral testicular pain as an acute aortic dissection symptom
Authors: Guarín-Loaiza Gloria Mercedes , Nocua-Báez Laura Cristina , Alfonso-Hernández Gladys
Published: January 2017

Acute aortic dissection is a serious cardiovascular event and the most common acute disease of the great vessels. According to the anatomical distribution of the compromised aorta, the Stanford Group classifies it into type A and type B. Its prognosis depends on its early identification and treatment, as the mortality rate in type A increases rapidly with each hour of delay of diagnosis.Clinical manifestations of aortic dissection may be varied, which makes its early diagnosis difficult. Regarding its diagnosis, genital pain is one of the rarest symptoms. In this paper, the case of a patient who initially attended a health care institution due to acute bilateral testicular pain and was eventually diagnosed with acute aortic dissection is presented.
Recommendations on treatment of nail and fingertip injuries in children. Cases series and literature review
Authors: Vergara-Amador Enrique , Castillo Pérez Sergio , Tovar Cuellar Wilson
Published: January 2017

Introduction: Nail and fingertip injuries in children are very frequent and may range from a simple nail or fingertip injury to amputations.Objective: To present a series of cases with their clinical and demographic characteristics and to describe the current concepts for the treatment of these injuries.Materials and methods: A series of cases presenting fingertip injuries was analyzed for six months. Epidemiology of injuries is described and the current concepts of their treatment are reviewed.Results: 60% of the injuries analyzed in this study occurred in male subjects; 88% of patients suffered crush injuries, the nail was affected in 98% of the cases, sterile matrix damage was observed in 64% and germinal matrix damage was experienced in 34% of the cases. The soft tissue around the finger was affected in 40% of the cases and associated fractures were observed in 55% of the cases.Conclusion: Fingertip crush caused by closing doors was the most frequent injury, which implied a higher involvement of the nail. An adequate treatment focused on the anatomic repair of the nail bed, the relocation of the nail plate and, in some cases, the use of flaps to cover defects in the soft tissue is ideal for this type of injuries, and must be provided as fast as possible to avoid secondary deformities.
One hundred years after the expedition by Harvard University to Peru to investigate Carrion’s disease. Lessons for science
Authors: Salinas-Flores David
Published: January 2017

In 1913, around 100 years ago, the Harvard University sent an expedition to Peru, led by Richard Strong, to investigate Carrion’s disease. This paper provides a critical review of the scientific research carried out in this expedition.Richard Strong was a physician who performed unethical human experimentation in the Philippines and China. In Peru, Strong conducted experiments on humans to inoculate wart secretions to a psychiatric patient, which led him to replicate the Peruvian wart in this individual, although he could not replicate Oroya fever. Based on this experiment, and without taking into account epidemiological and clinical evidence, the Harvard expedition erroneously concluded that Oroya fever and Peruvian wart were two different diseases.A retrospective review of the scientific work conducted by the expedition in Peru allows drawing the following lessons for science: a) disapproving unethical human experimentation conducted by the expedition; b) to determine the cause of infectious diseases, it is necessary to obtain the best scientific, experimental and observational evidence, and c) to acknowledge that, despite the poor infrastructure, researchers in developing countries are able to produce high-quality scientific knowledge that may surpass the knowledge generated by researchers in developed countries.
Association between anger management and cigarette consumption in adolescents
Authors: Cogollo-Milanés Zuleima , Gómez-Bustamante Edna Margarita
Published: January 2017

Introduction: Cigarette smoking in adolescents is associated with a set of variables such as sex, age, anxiety disorders, depression and secondhand smoke (parents, siblings and friends). However, the association between anger management and smoking among adolescent students has been poorly studied in Colombia.Objective: To quantify the association between anger management in high school students in Cartagena, Colombia.Materials and methods: A cross-sectional survey designed for adolescent students of sixth and seventh grade in high school. Anger management was quantified through a seven-item version of the Spielberger’s Inventory for State-Trait Anger Expression (Cronbach’s alpha: 0.73) and through the input of the participants who have smoked at least once.Results: A total of 1 090 students between ages 10 to 18 (µ=12.3, σ=1.1), attending sixth and seventh grades, took part in the study; 565 (52.1%) were female. A group of 269 students (24.7%) reported low anger control, and 127 (11.7%) stated they had smoked at least once. After age and sex adjustment, the association between anger and smoking was not statistically significant (OR=1.35; 95%CI: 0.89-2.04).Conclusions: Anger management is a variable independent from cigarette smoking among teenager students.
Creation and initial development of the Radiology Service of the Faculty of Medicine from the Universidad Nacional de Colombia. One hundred years
Authors: Hulloa-Guerrero Luis Heber
Published: January 2017

The first X-rays laboratory of Hospital San Juan de Dios in Bogotá was acquired by the board of directors of the Faculty of Medicine and Natural Sciences of Universidad Nacional de Colombia, and was opened in September 1917. This laboratory was created in order to modernize the attention of patients and to promote medical education. Radiology, as a subject, was first introduced to the Medicine program curriculum of this university in 1928. It is important to note that before Gonzalo Gómez Esguerra became the first Colombian director of the laboratory, three radiologist from abroad had already taken this position.
INOVASI DALAM PRODUKSI CALON INDUK IKAN MAS (Cyprinus carpio L.) MELALUI BACKCROSS
Authors: Purwanto Joko , Prayoga Teguh , Juanda Tatang , Hidayat Rahmat
Published: January 2017

Kegiatan inovasi dalam produksi calon ikan mas dalam tahun 2012 ini diharapkan menjadi sumbangan BBPBAT Sukabumi dalam menyediakan, mendistribusikan, dan mendiseminasikan produk ikan mas yang dihasilkan untuk menunjang peningkatan produksi ikan mas di masyarakat. Dalam kegiatan ini, inovasi yang dilakukan adalah melalui penerapan backcross. Melalui backcross, diharapkan ada kontribusi keragaman genetik induk awal (F-2) dalam turunannya, F-1b. Oleh karena itu, maka di samping bertujuan untuk mengetahui kombinasi perkawinan terbaik, kegiatan ini sekaligus juga dapat digunakan untuk memproduksi calon induk. Kombinasi perkawinan terbaik untukperforma pertumbuhan panjang dan bobot dihasilkan adalah antara F-5 x F-5. Kegiatan backcross ini juga telah menghasilkan calon induk sebanyak 6.000 ekor dengan rincian ukuran 500-700 g sebanyak 2.100 ekor, 900 ekor ukuran 500-1.500 g. Sebagian di antaranya telah didistribusikan ke BBI Muntilan, BBI Wanayasa, BBAT Mandiangin, BBAT Tatelu, dan BBI Cikonyal Bandung, masing-masing 100 ekor jantan dan 100 ekor betina berukuran 200-250 g/ekor serta 3.000 ekor ukuran 50-100 g digunakan untuk kegiatan vaksinasi oleh kelompok kesehatan ikan di BBPBAT Sukabumi.
Logic Structure Determination (LSD) as a Computer Assisted Structure Elucidation (Case) for Molecular Structure Determination of Cytotoxic Cembranoids from Soft Coral
Authors: Januar Hedi Indra , Zamani Neviaty Putri , Soedharma Dedi , Chasanah Ekowati
Published: January 2017

The tropical Indonesian soft corals are a valuable resources that produce pharmacological cytotoxic cembranoids. However, manual structure determination into these compounds requires adequate knowledge of organic chemistry. This study presents the application of Logic Structure Determination (LSD), as a freeware Computer Assisted Structure Elucidation (CASE) for automatic molecular structure determination of cembranoid compounds from soft corals species. 12 Nuclear Magnetic Resonance (NMR) dataset of cytotoxic cembranoids were used to evaluate the accuracy of LSD in generating the possible structures. Results of this study shows LSD  generated numerous possible molecular structures, as the data input file derived only from 2D-NMR HMQC (Heteronuclear Multiple-Quantum Correlation), COSY (Homonuclear Correlation Spectroscopy), and HMBC (Heteronuclear Multiple Bond Correlation). The accuracy significantly enhanced (only 2-4 possible cembranoid structures from each NMR dataset) with addition of H2BC (Heteronuclear  2 Bond Correlation) experimental data. This may indicates that VLRC (Very Long-Range Correlations) affects significantly to LSD capability. Furthermore, LSD with direct 2 bond NMR experimental data is a reliable CASE technique for identification of cembranoid compounds. In general, this freeware-CASE is potential to be applied to other type of small molecule compounds and may serves as a potential solution for elucidation bottleneck step in Indonesian natural products studies.
Thyroid hormone status in children with protein energy malnutrition a hospital based case control study
Authors: Dhanjal Gurdeep S. , Singh Mrigind
Published: January 2017

Background: WHO estimates that about half of all deaths, occurring among children aged less than five years in the developing countries, can be attributed to malnutrition. In malnourished children various endocrinal changes are noted. There is reduced synthesis of plasma proteins that affects secretion and metabolism of thyroid hormone. The present study has been conducted to study the effect of protein energy malnutrition (PEM) on thyroid hormone and plasma protein levels; and to find correlation between thyroid hormones and plasma protein levels in PEM children.Methods: A cross sectional hospital based case-control study was carried out in tertiary care hospital of Northern India. 50 children with PEM, and equal number of age and sex matched healthy controls (1-5 years) were included in the study. Detailed clinical assessment of nutritional status followed by anthropometric measurement was recorded in a predesigned performa. The cases were categorized into moderate and severe malnutrition as per WHO classification (weight for height). Free Triiodothyronine (fT3), free Thyroxine (fT4), thyroid stimulating hormone (TSH), serum total protein and serum albumin were estimated. The parameters were compared among cases and controls using appropriate statistical tool. Results: Mean hemoglobin, serum protein, serum albumin, fT3, fT4 and TSH levels were significantly low in case group, when compared to the control group (p <0.001).The levels of biochemical variables, decreases as the severity of malnutrition increases. The difference within the cases (moderate and severe malnutrition) was also found to be statistically significant (p <0.001).Conclusions: PEM is associated with decrease level of thyroid hormone levels and were positively correlated with serum total protein and albumin levels. The decrease level of thyroid hormone may have a contributory role in retarded growth and development.
The evaluation of the Higher Education lecturer competences in East Timor: a student inquiry
Authors: Belo Abílio António Freitas
Published: January 2017

Several studies have demonstrated the impact that the quality of teacher education has on teaching and student performance. The assessment of the competences of higher education teachers by students is one way of assessing the quality of teachers and, therefore, the quality of public higher education itself. It is therefore pertinent to carry out empirical studies that make it possible to understand how students evaluate teachers' competences.

The objective of this study was to evaluate the competences of higher education teachers in the public university of East Timor, based on the students' opinion. Using a random sample of 342 students enrolled in four of the nine faculties of the National University of East Timor (UNTL), surveys were carried out to evaluate the pedagogical, professional, social and personality traits of teachers. The results showed a positive evaluation by the students, although the objectives of the National Strategic Plan for Education 2011-2030 (METL, 2011) have not yet been fully achieved.
UPACARA JIB BOK, MAI SONG, SANG CONG, DAN JIB GONG DALAM KHONGHUCU
Authors: Darno Darno
Published: January 2017

Most of the death ceremony for Chinese descendant who are Khonghucu
follower are similar particularly in Singkawang and generally in Indo­
nesia.

For instance, a Jib Bok ceremony, which is a ceremonial to enter the
death people inti the box. Mai Song that is a ceremonial before depar­
ture to the cemetery held in the evening. Song Cong is a departure ritual,
and Jib Gong is a buried service.
PENGEMBANGAN INSTRUMEN PENILAIAN RANAH AFEKTIF MATA PELAJARAN AQIDAH AKHLAK
Authors: KUSUMAWATI TRI
Published: January 2017

Penelitian ini bertujuan untuk mengembangkan instrumen penilaian ranah afektif mata pelajaran Aqidah Akhlak dan menyusun panduan tentang instrumen   penilaian ranah afektif yang teruji valid dan reliabel. Pendekatan penelitian yang digunakan adalah R and D dengan mengadaptasi prosedur pengembangan dari Borg dan Gall tanpa tahapan yang terakhir, yaitu diseminasi dan implementasi. Analisis data menggunakan pendekatan kuantitatif, yang meliputi uji validitas, uji reliabilitas, dan uji generalisabilitas antar rater. Pengembangan instrumen menghasilkan sebuah produk yang berupa buku Panduan Instrumen Penilaian Afektif. Buku panduan memuat instrumen angket skala sikap, instrumen observasi, dan instrumen wawancara. Hasil uji empiris di lapangan menghasilkan item- item pernyataan yang valid dan mempunyai tingkat reliabilitas yang tinggi. Buku panduan dapat dimanfaatkan oleh guru dalam melakukan penilaian afektif yang lebih obyektif dan komprehensif sehingga menghasilkan penilaian yang lebih bermakna.

 

Kata kunci: instrumen penilaian; penilaian afektif; aqidah akhlak.
INTERNALISASI NILAI-NILAI KARAKTER BANGSA MELALUI MATA PELAJARAN PENDIDIKAN AGAMA ISLAM PADA SMA EKS-RSBI DI TEGAL
Authors: Sofanudin Aji
Published: January 2017

Penelitian ini bertujuan untuk memahami proses internalisasi nilai-nilai karakter bangsa melalui mata pelajaran Pendidikan Agama Islam (PAI). Dengan menggunakan pendekatan kualitatif model CIPP (Context, Input, Process, Product) penelitian ini menghasilkan empat temuan, yaitu: (1) secara konteks, strategi penanaman nilai-nilai karakter bangsa melalui mata pelajaran agama dilakukan melalui kebijakan kepala sekolah, sistem sekolah, kualitas sarana dan prasarana, serta iklim dan budaya yang mendukung internalisasi pendidikan karakter di sekolah; (2) secara input, internalisasi nilai-nilai karakter bangsa telah dilakukan melalui kualifikasi dan kompetensi guru, input sarana dan prasarana, serta kualifikasi peserta didik; (3) proses internalisasi nilai-nilai karakter bangsa dilakukan melalui kurikulum PAI berupa kegiatan intrakurikuler, kegiatan ekstrakurikuler,  dan pembiasaan sekolah; (4) produk yang dihasilkan dari internalisasi  nilai-nilai karakter bangsa melalui PAI adalah peserta didik yang kompeten dan memiliki karakter yang baik.

Kata kunci: Internalisasi, Nilai-nilai Karakter, CIPP, SMA eks-RSBI
PSYCHOPHYSICAL HEALTH DURING PROLONGED UNEMPLOYMENT: LONGITUDINAL DATA
Authors: Majstorović Nebojša , Popov Boris , Matanović Jelena , Slijepčević Vanja
Published: January 2017

Research on health effects of unemployment have shown inconsistent findings, both in terms of stability and factors of overall health during time without a job, and in terms of the significance of factors based on which one can reliably predict the health of the unemployed. The Psychophysical health scale was conducted on a sample of 222 unemployed individuals in the Republic of Serbia, in order to analyze factors of general psychophysical health. By applying a longitudinal study design, we measured general health of the unemployed from four regions in the Republic of Serbia on three occasions (March 2012, October 2012, and May 2013). During the course of the study, the results have indicated that, unemployed individuals show significantly fewer symptoms of ill-health, that women, as a group, are more vulnerable in most aspects of health, that the oldest unemployees report symptoms of health deterioration most often, and that job loss does not produce different effects on health in people with different levels of education. These results are discussed in light of findings from previous research studies.
GENERATIONAL DIFFERENCES IN PSYCHOLOGICAL CONTRACT CONTENT AND REACTIONS TO PSYCHOLOGICAL CONTRACT BREACH IN THE TRANSITION CONTEXT: A STUDY OF CROATIAN EMPLOYEES
Authors: Dautović Mojra , Galić Zvonimir
Published: January 2017

In our study we explored generational differences in psychological contract content (PCC) and reactions to psychological contract breach (PCB) among Croatian employees. We collected the data on a sample of 432 participants and compared the PCC between Generation Y (born from 1981 to 1993) and older employees (born between 1946 and 1980). The results showed that the Generation Y employees expected more from their employers regarding career development, work-life balance, and social atmosphere. At the same time, the older generation perceived stronger employer obligations related to organizational policy, and stronger employee obligations related to in-role performance. We also tested the moderating effect of age on the relationship between PCB and job attitudes (job satisfaction, organizational commitment, and turnover intention). The moderating effect was observed only for the relationship between PCB and turnover intention: the younger employees reacted to PCB with a stronger turnover intention than the older employees.
Safety management on the poultry farm
Authors:   University of Maryland, USA, Joo Jungsoo , Pradeep Rao Aishwarya ,   University of Maryland, USA,   University of Arizona, USA, Biswas Debabrata ,   University of Maryland, USA
Published: January 2017

Transmission and colonization of poultry pathogens and infectious diseases can be controlled, and the colonization of major zoonotic pathogens in the poultry can be minimized, through better farm safety management, phytosanitary measures and a pre-harvest Hazard Analysis and Critical Control Point (HACCP) system. Such safety management practice can also significantly reduce food safety challenges that are present during post-harvest processing and packaging, improve the microbial quality of poultry products, better protect consumer health and mitigate environmental contamination. Appropriate control of pest and wildlife infiltration and a well-designed, low-stress environment are fundamental to maintaining optimal flock health. Safety training and education of breeders, farmers, suppliers and workers are essential to produce healthy birds while ensuring that poultry farming remains sustainable and economical.
The emergence of antibiotic resistance in poultry farms
Authors:   The Ohio State University, USA, Kassem Issmat I. , Helmy Yosra A. ,   The Ohio State University, USA, Kashoma Isaac P. ,   The Ohio State University, USA, Rajashekara Gireesh ,   The Ohio State University, USA
Published: January 2017

The use of antibiotics in poultry farming has enhanced production via effectively controlling infectious diseases and promoting growth of birds, allowing the industry to cope with the increasing consumer demands and provide safe and affordable products. However, the use of antibiotics results in the selection of antibiotic-resistant bacteria, including established animal and human pathogens. The emergence and proliferation of resistant pathogens and the cognate decrease in the efficacy of antibiotic therapy pose a concrete risk to public health and sustainable farming. Consequently, the need to tightly regulate the use of antibiotics in poultry farming has been highlighted as a pre-emptory necessity.
Influence of ultrasonic activation in association with different final irrigants on intracanal smear layer removal
Authors: Souza Matheus Albino , Motter Felipe Trentin , Fontana Tobias Pitton , Ribeiro Marlos Barbosa , Miyagaki Daniela Cristina , Cecchin Doglas
Published: January 2017

Aim: To evaluate the influence of ultrasonic activation (US) with different irrigant regimens in smear layer removal. Methods: One hundred bovine incisors were instrumented and divided into ten groups (n=10) according to final irrigation protocols: distilled water (DW); DW+US; 17% EDTA; QMix; 10% citric acid; 37% phosphoric acid; 17% EDTA+US; QMix+US; 10% citric acid+US; 37% phosphoric acid+US. The samples were then submitted to scanning electron microscopy where a score system was used to evaluate the images and effectiveness of proposed treatments. The data were statistically analyzed by Kruskal-Wallis and Mann-Whitney U tests for intergroup comparisons as well as the Wilcoxon and Friedman tests for intragroup comparisons at 5% significance level. Results: In the cervical third, groups 17% EDTA, QMix, 10% citric acid, 17% EDTA+US, QMix+US and 10% citric acid+US were more effective in smear layer removal (p<0.05); in the middle third, groups 17% EDTA+US and QMix+US were more effective in smear layer removal (p<0.05); in the apical third, groups 17% EDTA,17% EDTA+US and QMix+US were more effective in smear layer removal (p<0.05). Conclusions: US can aid 17% EDTA and QMix in smear layer removal at the middle third and QMix at the apical third, contributing to the cleaning of root canal system.
Expression of TIMP-2 in HPV-16 infected oral squamous cell carcinoma in patients in Iraq
Authors: Manal Habib A , Huda Habib A , Israa Hussain A , Al-Salih Karima
Published: January 2017

Aim: To determine the expression of tissue inhibitors of metalloproteinases (TIMP-2) in oral squamous cell carcinoma (OSCC) and the difference in its expression level between positive and negative HPV-16 (human papilloma virus- 16) OSCC patients. Methods: This study was conducted on 33 biopsies obtained from patients with OSCC and 10 normal oral mucosa as controls. In situ hybridization (ISH) was used to investigate the presence of HPV-16, while immunohistochemistry (IHC) was used to estimate the expression level of TIMP-2. Results: The TIMP-2 was expressed in 27 (81.8%) of OSCC sections with no significant difference between its expression level in HPV-16 positive and HPV-16 negative OSCC cases (p=0.058). TIMP-2 was found to be highly expressed in OSCC sections, and the presence of HPV was not related to its overexpression. Conclusions: The percentage of samples that appeared to accommodate detectable HPV-16 was high, but no significant difference was observed in relation to TIMP-2 expression level. Future studies with a larger number of patients are highly recommended to address the possible association between TIMp-2 and OSCC positive HPV-16.
Jesuítas e embates para a inculcação da educação e da cultura europeia na América Portuguesa
Authors: Melo Jéssica Cristine de , Hernandes Paulo Romualdo
Published: January 2017

O presente artigo analisa os embates que os jesuítas enfrentaram para a inculcação da cultura e da educação europeia na terra dos brasis. A partir da leitura e análise de alguns documentos jesuíticos, percebe-se que houve resistência por parte dos nativos das matas à interferência dos religiosos em sua cultura e educação. Aconteceram, também, conflitos no interior da Companhia de Jesus e mesmo entre religiosos de outras ordens e hierarquias da Igreja Católica para a realização de um modo de educar realista, iniciado por Nóbrega, de enfrentamento da realidade brasileira, que Saviani nomeou pedagogia brasílica.
As tarefas escolares e o ensino desenvolvimental
Authors: Miranda Made Júnior
Published: January 2017

Este texto buscou reunir contribuições sobre os procedimentos pedagógicos e didáticos no contexto do desenvolvimento das “tarefas escolares”. O estudo foi com base da teoria histórico-cultural da atividade dos psicólogos da educação russa expressados na Teoria do Ensino Desenvolvimental de Vasili V. Davídov. A demanda está centrada na ideia de que as ‘tarefas escolares’ são ações que se inserem no próprio processo de ensino valorizando a sua essência dialética e transformadora do potencial dos indivíduos em constante desenvolvimento. A finalidade foi incitar os leitores no sentido produzir ideias capazes de influenciar consideravelmente no contínuo processo transformador que regula o ato de ensinar e de aprender no campo prático. A revisão e análise de literatura discutiu as tarefas no contexto escolar e os pressupostos da Teoria do Ensino Desenvolvimental na relação com as tarefas escolares. Concluiu-se que o trabalho com as tarefas no ensino desenvolvimental é uma perspectiva superadora de educação e acontece vinculado a uma estrutura de atividade humana que integra indissociavelmente o saber, o aluno e o professor na atividade propositiva.
O manifesto dos pioneiros da educação nova e a defesa da ordem: O embate entre liberais e católicos no campo da educação
Authors: Oliveira Marco Antonio
Published: January 2017

O presente texto analisa as determinações mais amplas que constituíram os embates presentes no campo da educação que permearam a publicação do Manifesto dos Pioneiros da Educação Nova no cenário marcado pelas disputas entre liberais e católicos. Objetiva situar os distanciamentos e aproximações entre os dois grupos que apesar das diferenças existentes, defendiam a ordem regida pelo capital. Tomamos como parâmetros de nossas análises, além do Manifesto dos Pioneiros da Educação Nova, os trabalhos de Saviani (2008), Xavier (2002), Lemme (2005) Azevedo (1976), Nagle (1974), entre outros.
A hegemonia do projeto educativo do empresariado no Brasil e em Portugal
Authors: Souza Camila Azevedo
Published: January 2017

Este trabalho analisa o movimento da responsabilidade social, tendo em vista os projetos educativos da organização empresarial brasileira Gife (Grupo de Institutos, Fundações e Empresas) e da organização empresarial portuguesa Epis (Empresários pela Inclusão Social). Com base no materialismo histórico e, mais especificamente, nas formulações de Antonio Gramsci, o objetivo é identificar os modos de pensar, agir e sentir disseminados por essas entidades empresariais para apreender o processo de hegemonia que legitima a cultura empresarial nas políticas educacionais e reafirma os interesses da classe dominante no conjunto das relações sociais.
Imagens da mulher na ciência e na ficção de Afrânio Peixoto: a esfinge e elementos medicina legal em debate
Authors: Silva Maria Lourdes , Moreira Helena Maria Alves
Published: January 2017

Este trabalho analisa as formas como a mulher é apresentada em duas obras de Afrânio Peixoto (1876-1947) escritas entre 1910-1: o romance A Esfinge e o manual didático, Elementos de Medicina Legal. Os contemporâneos do médico baiano costumavam aclamar sua competência profissional e inteligência solicitando circulação e adesão do polígrafo à rede institucional constitutiva do aparato administrativo estatal, corporativo ou editorial, aos quais Afrânio selava alinhamento através de sua obra escrita. A educação da mulher, o seu lugar na sociedade e os papeis a ela cabíveis são temas que ocupam o autor e filtro de nossa investigação nas obras citadas. Formado na tradição da ciência criminológica do final do século XIX e início do XX, a relevância do presente trabalho está em refletir sobre como a literatura “peixotiana” traz à cena as teorias eugenistas e os preconceitos sociais pelas caracterizações de suas personagens, forçando-nos a repensar a genialidade atribuída ao autor e os limites entre a poética literária e a escrita científica em sua obra. Como resultado desse estudo, indicamos as imprecisões entre ciência e moral no pensamento do autor, o que acarreta manutenção de explicações organicistas justificando o lugar da mulher na sociedade.
Web Intelligence and Artificial Intelligence
Authors: Takama Yasufumi ,   Tokyo Metropolitan University
Published: January 2017

This paper briefly summarizes the progress of artificial intelligence (AI) and web intelligence (WI) in the last two decades. The reason why we mention AI and WI together is because those have strong relationship with each other. This paper first summarizes the history of AI, and then gives brief description of supervised learning, which I think has played a major role in AI in the last two decades. As most history of WI is in the target decades, this paper first briefly describes major WI topics, and then gives more detailed description about information recommendation, which I think one of more successful and necessary technologies in practical use.