bluuebunny/crossref_metadata_2025 huggingface dataset:
Le Huu Trac - Anton Chekhov: Points of contact in medical practice and literary activity
Authors: Britov Igor V.
Published: June 2022

The article uses comparative methods to research literary activity and medical practice of Vietnamese and Russian writers, Le Huu Trac and Anton Chekhov, including the way their medical skills and ethics manifested themselves in literary works. Although Le Huu Trac and Anton Chekhov belong to different cultures and epochs and have different “literary weight,” the comparative analysis of their medical practice and literary activity reveals certain similarities in Vietnamese and Russian literatures, which could be explained in the absence of mutual influence with the universal laws of human consciousness, in a particular case - by the patterns of consciousness inherent in a doctor-writer. The study of works by the writers, who never met either in space or in time, confirmed the universality of main functions of literature. At the same time, it is noted that the prioritization of functions (cognitive, evaluative, educational, aesthetic, and self-expression) is different for each national literature and each author. It has been revealed that the depiction of nature has a great ideological and semantic meaning in the works of Vietnamese and Russian medical writers. The analysis allowed to identify similar images of nature, which are often found in these authors’ works, although the meaning of these images may be different, as determined by different cultural systems. Similar literary images and artistic techniques were detected, in addition to the materialistic outlook of both Le Huu Trac and Anton Chekhov. The author points out that medical knowledge and medical ethics had a significant influence on the work of Le Huu Trac and Anton Chekhov. There are certain similar principles in the presentation of "medical material" in their literary works. The study supports the comparativist conclusion about “cross-cutting processes” in world literature.
Two-world Nature of Sibel Atasoy's Fantasy
Authors: Repenkova Maria M.
Published: June 2022

Modern Turkish mass literature is extremely diverse. Fiction has taken a special place among the popular genres in 2000. Fiction, in turn, is largely defined by the genre of fantasy, which has become a mainstream one. Genre forms classification of Turkish fantasy is still in its formative stages. However, three sub-genres of fantasy are clearly present in Turkish literature. These are sword and sorcery fantasy, urban fantasy and dark fantasy. Each of these genres blends two worlds - the real one and the magic one - mixing two together and splitting the timeline of the work, causing the reader to doubt the reality of the events. In the sword and sorcery fantasy, the magical events appear mostly in the background of the Middle Ages, whereas in the urban and dark fantasy, modern times become the main setting, making it more multilayered and colourful.
In Sibel Atasoy's novel The Grinning Red Moon (2000), the two-world nature of fantasy literature can be observed at all levels of a fiction text, presented as a monologue of the protagonist. Her monologue narration often disrupts time and space layers, aiming to better represent the character of a woman narrator who was also split into two. The protagonist's narrative clearly shows how her past and present are intertwined, how they become equal, and how the past finally replaces the present. The past and the present protagonists are two very distinct people in terms of psychology, trying to find contact with each other
Significance of D-dimer in Assessment of Severity and Mortality of COVID-19 Patients A Tertiary Care Hospital Study
Authors: Suruthy Ashwini , Vishwanathan Neethu Gowdru , Bijjaragi Seema
Published: June 2022

The outbreak of COVID-19 has brought public health emergency worldwide and has been the biggest challenge to date. This study aims to study the correlation between D-dimer levels with severity and mortality in COVID-19 patients. This study will help us understand the disease's progression and monitor the disease severity and mortality in Covid-19 patients. This retrospective descriptive study was conducted over four months from April 2021- to June 2021 in a tertiary care hospital in Central Karnataka. Demographic details and clinical and laboratory parameters were obtained from electronic hospital records. Inclusion criteria are Patients who were RT-PCR confirmed positive cases were only included in this study. Exclusion criteria are Patients who had cancer, hematologic malignancies, and acute coronary syndrome were all excluded. Results of the research are A total of 75 cases were evaluated and analyzed in this study. Patients were categorized based on severity as mild to moderate and severe. Out of which 50 patients had recovered from the illness, and 25 patients have succumbed to death. Our study revealed that elevated D-dimer levels were significant (p<0.02) with the outcome of the disease, and with the mean level of 929.27 in severe patients and 466.47 in mild-moderate patients, elevated D-dimer were highly significant (p<0.001) with the severity of the disease. Conclusion research detailed investigations of 75 COVID-19 patients suggests that a significant increase in D-dimer levels was associated with mortality and severity of the disease. Therefore, we strongly recommend that the D-dimer be used to screen patients with COVID-19 to evaluate the severity and predict the prognosis and mortality in hospitalized COVID-19 patients during admission and follow-up throughout hospitalization.
Interaksi Sosial Sesama Rekan Kerja Dengan Intensi Turnover Karyawan PT. Xuilong Outdoor
Authors: Alif Dian Cahyaning Tyas  , Vitri Yuniarti
Published: June 2022

The purpose of this study is to determine whether there is a relationship between the social interaction between coworkers and employee turnover intentions.The hypothesis proposed is that there is a link between the social interaction between colleagues and employee turnover intentions. Research subjects were 50 employees of PT. Xuilong Outdoor Tunggorono recruited through the Purposive random sampling technique. The independent variable chosen was the social interaction between colleagues. While, the dependent variable is the Turnover Intention. The data collection tools consist of a social interaction scale and a Turn over intention scale. Analysis of hypothesis testing using Spearman's Rho correlation analysis. Result of research rho XY = 0,-234; with p = 0.102 (p > 0.05). This indicates that the hypothesis is rejected, meaning that there is no correlation between Social Interaction among Coworkers and Employee Turnover Intentions at PT. Xuilong Outdoor Tunggorono Jombang
SISTEM INFORMASI PEMBAYARAN IURAN SEKOLAH SISWAPADA SMK YAYASAN BAKTI PRABUMULIH DENGAN METODE WATERFALL
Authors: Suhartini Suhartini , Purbasari Yuntari
Published: June 2022

Kajian ini bertujuan untuk membangun suatu sistem informasi pembayaran spp. Sistem ini dikembangkan dengan menggunakan perangkat lunak NetBeans IDE 7.4, iReport-5.6.0, dan XAMPP 1.7.3. Sistem ini bekerja untuk dapat memasukkan data transaksi pembayaran biaya pendidikan, seperti spp, biaya seragam, biaya pendaftaran serta membuat laporan pembayaran secara otomatis. Tujuan sistem ini adalah untuk mempermudah staf atau pegawai administrasi dalam melakukan transaksi pembayaran spp.Sistem pembayaran SPP yang efektif akan memicu kinerja dari instansi untuk menjadi lebih baik dari sebelumnya. Untuk itu diperlukan adanya sebuah sistem yang mampu menangani proses pembayaran SPP. Dengan menggunakan sistem pembayaran SPP ini diharapkan dapat membantu kinerja pihak instansi. Dengan di terapkannya sistem ini pada SMK Yayasan Bakti Prabumulih dapat mengurangi kesalahan-kesalahan pembayaran yang mungkin terjadi. Sistem ini juga dapat mempercepat proses pembayaran dan pembuatan laporan yang pada akhirnya dapat membantu SMK Yayasan Bakti Prabumulih.
Pengaruh tingkat kesehatan bank terhadap profitabilitas perusahaan perbankan yang terdaftar di BEI tahun 2016-2020
Authors: Kurniawati Nita , Nasrifah Batara Daniel
Published: June 2022

In the world of banking, profitability is important for market participants. The increase in profitability is a good signal for market participants. This study aims to examine the effect of the soundness of banking seen from LDR, NPL, and CAR on profitability. The method used in this research is descriptive quantitative. The analysis technique uses multiple linear regression analysis with the help of the EViews 12 program. The results show that LDR has no effect on profitability, which means that the LDR of banks listed on the IDX does not affect the magnitude of profitability, NPL and CAR have a negative effect on profitability, which means that if the A low NPL indicates that the level of risk in lending to banks is low enough so that the bank will experience profits and the level of profit earned by the bank is not significantly affected by the size of the CAR ratio.
Pengaruh kepemilikan institusional, kepemilikan publik dan profitabilitas terhadap penghindaran pajak dengan manajemen laba sebagai variabel intervening
Authors: Edastami Mayangsari , Kusumadewi Yunita
Published: June 2022

The purpose of this study was to determine whether there is an effect of institutional ownership, public ownership and profitability variables on tax avoidance with earnings management as the intervening variable..The research approach used in this research is quantitative research with causality type. The sample used was 13 companies during the 6-year study period (2015-2020) or 78 samples. Hypothesis testing using Sobel test (criteria from mediation). Sobel test is used to determine the effect of the mediating variable, namely earnings management. Based on the results of the tests that have been carried out, this study concludes that institutional ownership and public ownership have no effect on earnings management. profitability have an effect on earnings management.However, institutional ownership and profitability have no effect on tax avoidance, public ownership have an effect on tax avoidance. Meanwhile, earnings management is not able to mediate the variables of institutional ownership, public ownership and profitability on tax avoidance.
Analisis dampak keberadaan wisata edukasi kampung coklat terhadap perubahan perekonomian masyarakat di Desa Plosorejo Kabupaten Blitar
Authors: Dewi Velina Sari , Mukhlis Imam
Published: June 2022

This study aims to analyze the educational conditions of the chocolate village and analyze the impact of the existence of chocolate village educational tourism on changes in the economy of the people of Plosorejo Village, Blitar Regency. This study uses qualitative data types and qualitative data with samples of educational tourism in Kampung kuning and the surrounding community who work around educational tourism in Kampung kuning. Data analysis from observations, interviews and documentation was carried out by transcribing the interview data from the manager of the Kampung Chocolate Educational Tourism and the surrounding community, then coding on the themes according to the research title. To test the validity of the data in this study, the technique used is using triangulation techniques. The conclusion in this study is that this Kampung Chocolate Educational tour, is very influential on the community, especially in encouraging the economy of the Plosorejo Village community, can provide job opportunities and job opportunities for the community. In the beginning, people who did not have jobs, worked odd jobs, farmers, and former thugs could work as employees at the Chocolate Village Educational Tour and could open up business opportunities. With job opportunities, the wheels of motion would also decrease.
Sharing Economy and its impacts on modern consumption
Authors: Munaro Cristina , Bertoldo Jeferson
Published: June 2022

This work analyzes the Sharing Economy and its impacts on modern consumption. Such an approach is due to the fact that the sharing economy is a new benefit to consumers and a nuisance to traditional companies, as it is more economical. The objective of this study is to analyze how the Sharing Economy has been transforming the way companies innovate and the behavior of people. This purpose will be achieved from the bibliographic research, where all the information collected will be analyzed. The research showed how important this new economy is, how it is changing the way of consuming certain services and their benefits compared to the traditional one.
РОЗВИТОК SOFT SKILLS МАЙБУТНІХ УЧИТЕЛІВ ПОЧАТКОВИХ КЛАСІВ ЯК ЗАСІБ АКМЕОЛОГІЧНОГО ЗРОСТАННЯ
Authors: Демченко Олена , Казьмірчук Наталія , Стахова Інна
Published: June 2022

Актуальність: сучасне суспільство потребує нових прогресивних педагогів, здатних виховати гуманне, цілеспрямоване покоління, яке працюватиме на розвиток власної держави; це зумовлює підвищення уваги до підготовки майбутніх учителів, розвитку їхніх soft skills, формуванні внутрішньої потреби перебувати в епіцентрі освітніх новинок, займатися саморозвитком та педагогічним зростанням.
Мета: здійснити діагностику розвитку soft skills майбутніх учителів початкової школи; запропонувати напрями розвитку гнучких навичок студентів у сучасному закладі вищої освіти.
Методи: теоретичні (аналіз наукової та методичної літератури, узагальнення, систематизація інформації); емпіричні (спостереження за педагогічною діяльністю студентів у ході ділових ігор та під час педагогічної практики), аналіз творчих робіт, опитування, тестування.
Результати: проведено дефінітивний аналіз та визначено основні напрямки розуміння гнучких навичок в педагогічному процесі; відповідно до проведених науково-педагогічних досліджень запропоновано різні класифікації груп гнучких навичок; визначено, що на низькому рівні розвинені soft skills у 24 (29,3%) студентів, на середньому – у 35 (42,7%), на достатньому – у 17 (20,7%), а на високому – у 6 (7,3%); акценовано увагу на формах роботи зі студентами, запропоновано методичні рекомендації для розвитку гнучких навичок майбутніх учителів.
Висновки: результати, отримані в результаті дослідження, дозволили чітко визначити подальші напрями роботи з розвитку soft skills студентів, спланувати подальшу участь майбутніх учителів у низці професійних заходів (конференцій, вебінарів, майстер-класів тощо); запропоновано напрями розвитку гнучких навичок студентів у контексті акмеологічного підходу (організація творчого освітнього простору, що забезпечує кожному студентові вільний вибір навчальних предметів та професійний ріст; використання інноваційних технологій та акмеологічних моделей, спрямованих на професійний розвиток кожного педагога; залучення студентів до різних видів пізнавальної діяльності в освітньому процесі; організація спільної творчої діяльності, діалогічної взаємодії студентів і викладачів, спрямованих на формування цілісної особистості майбутнього фахівця; стимулювання рефлексивної оцінки студентом власної педагогічної діяльності).
Pengaruh Modal Kerja Terhadap Profitabilitas Perusahaan Perdagangan Eceran di Bursa Efek Indonesia
Authors: Sukmadewi Refni
Published: June 2022

The purpose of this study is to determine the effect of working capital management which consists of: Cash Turnover, Accounts Receivable Turnover and Inventory Turnover on the level of profitability in retail trading companies listed on the Indonesia Stock Exchange in 2017-2019. This research uses quantitative research by observing and studying audited financial reports from retail trading companies listed on the Indonesia Stock Exchange during the study period. The analysis method used is multiple regression analysis. The sample of this study amounted to 14 companies. The results of this study indicate that partially working capital management which consists of: Cash Turnover has a positive effect on Profitability, Receivables Turnover has a positive effect on Profitability and Inventory Turnover has a positive and significant effect on profitability in retail trading companies listed on the Indonesia Stock Exchange 2017-2019. Furthermore, simultaneously working capital management which consists of: Cash Turnover, Accounts Receivable Turnover and Inventory Turnover affect the profitability of 2017-2019 companies listed on the Indonesia Stock Exchange 2017-2019.

 

Keywords: Cash Turnover, Accounts Receivable Turnover, Inventory Turnover, Working Capital, Profitability
Banks in Midst of Fintech and Neobanks
Authors: Hidayat Adrian
Published: June 2022

In the year of 2021more and more challenging. The banking industry facing the urgency of  the fundamental reinforecement. No one can predict that the affect of COVID-19 pandemic has already 1 year and the waves affected financial and economy in the country.

The banking industry are suffering so much, and the intermediary system is quite slow, especially in the credit granting to banking-customer. The business is practically slowing down and even more, they are on the critical situations, therefore the credit-demand is also slowing down. At the same time, credit quality is becoming worse scenario, due to so many creditor facing bad business situation, and therefore they can not pay the credit installment.

On this 2021 situation, the banking industry can not wait preparing the future financial-technology (Fintech), such as developing the infrastructure as well as the products to gain more customer and giving more benefits on digital payment system.
Influence Of Auditor Switching, Audit Fee, Tenure Audit and Company Size To Audit Quality
Authors: Yanti Lia Dama , Wijaya Michael Darmawan Wijaya Darmawan
Published: June 2022

Audit quality is a function of the auditor's independence and competence of the company's management in examining and providing opinions on the company's financial statements so that the auditor can report violations in a financial statement. This study aims to determine the effect of auditor switching, audit fees, audit tenure and company size on audit quality in food and beverage companies listed on the Indonesia Stock Exchange for the period 2015-2018 This research is an Ex-Post Facto research with data collection methods using secondary data. The population in this study are food and beverage companies listed on the Indonesia Stock Exchange. The sampling technique used was purposive. The sample of companies amounted to 12 companies. Data analysis techniques in this study used a logistic regression test. The results shows: (1) Auditor switching has no effect on audit quality, with the significance value of 0.177> 0.05 (2) Audit fee has no effect on audit quality with a significance value of 0.046 <0.05 (3) audit tenure has no effect on audit quality with a significance value of 0.229> 0.045 (4) Firm size has no effect on audit quality with a significance value of F of 0.031 <0.05
Sentiment Analysis: The Water Crisis
Authors: Smeriglio Makenzie
Published: June 2022

This research examines the issue of the water crisis from an Indigenous Feminisms perspective. The First Nations Water Crisis is the issue of long-term water advisors that Indigenous communities have had and are currently still experiencing. It is a complex issue stemming from settler colonialism, and the broader Canadian public does not understand it well.

This research examines public sentiments in the comment sections of news stories about First Nations and the water crisis. This is to identify settler-colonial mythologies about Indigenous peoples and offer counter-narratives.

Clean water is a basic necessity and should be offered to everyone. By addressing hateful socio-political imaginaries and offering counter-narratives, we can work towards changing people's opinions from apathy to empathy. We can also work towards making real positive changes to the First Nations Water Crisis.
ОСНОВНІ ЧИННИКИ ФОРМУВАННЯ ВИДОВИХ ВИЩИХ ВІЙСЬКОВИХ НАВЧАЛЬНИХ ЗАКЛАДІВ НА ПРИКЛАДІ ВІЙСЬКОВО-ПОВІТРЯНИХ ТА ВІЙСЬКОВО-МОРСЬКИХ СИЛ ЗБРОЙНИХ СИЛ УКРАЇНИ
Authors: Корольов Станіслав
Published: June 2022

В даній статі висвітлюються основні заходи, які проводилися під час військового будівництва України в рамках створення системи вищих військових навчальних закладів видів Збройних Сил України для підготовки військових фахівців Військово-Повітряних Сил та Військово-Морських Сил Збройних Сил України. При цьому висвітлюються процеси щодо формування серед вищих військових навчальних закладів України саме таких, які мали готувати спеціалістів відповідного фаху для видів Збройних Сил України згідно їх майбутнього призначення щодо виконання бойових завдань. Також приводяться приклади виконання подібних заходів досвіду країн-членів НАТО, зокрема, США.

Ключові слова: вищі військові навчальні заклади, військові фахівці, види Збройних Сил України, підготовка, заходи, забезпечення, законодавство, формування, будівництво, Військово-Повітряні Сили, Військово-Морські Сили Збройних Сил України.
ТРАНСФОРМАЦІЯ ОРГАНІВ МІЖНАРОДНОГО СПІВРОБІТНИЦТВА МІНІСТЕРСТВА ОБОРОНИ УКРАЇНИ ТА ЗБРОЙНИХ СИЛ УКРАЇНИ
Authors: Сидоров Сергій , Попко Сергій , Гребенюк Михайло
Published: June 2022

Анотація. Мета дослідження – є розкриття еволюції створення системи органів міжнародного співробітництва Міністерства оборони та Збройних Сил України від її зародження до президентських виборів в Україні в 2019 р. Методологія дослідження спирається на принципах історизму, системності, науковості, авторської обʹєктивності, також на використання загальнона- укових (аналіз, синтез, порівняння, узагальнення) та спеціально-історичних (історико-статистичний, історико-системний) методів. Наукова новиз- на полягає у тому, що у статті вперше розкриваються еволюція та основні етапи розвитку органів міжнародного співробітництва Міністерства оборони України та Збройних Сил України від часу їх створення до виборів Президента України у 2019 році. Обґрунтована необхідність створення системи орга- нів міжнародного співробітництва, показаний склад структурних підрозділів, надається характеристика та спрямованість основних завдань, особливості їх виконання, розкрита обумовленість їх трансформації. На підставі аналізу кількості контактів різних видів і форм, прийнятих державних програм і планів, підписаних міжнародних договорів та угод, проведених спільних навчань та участі у миротворчих місіях запропонована періодизація інтенсивності міжнародного співробітництва. Висновки. Аналіз організаційних змін в органах міжнародного співробітництва показав, що з 1997 р. відбувся розподіл напрямів міжнародного співробітництва між Міністерством оборони та Генеральним штабом ЗС України, а самі органи неодноразово реформувалися. В цілому за роки незалежності у Збройних Силах України була створене дієз- датна система органів міжнародного співробітництва, яка своєчасно реагувала на зміни політичної обстановки, забезпечувала інтенсивність контактів у різних сферах та напрямах, сприяла реалізації потенціалу Збройних Сил України.Ключові слова: міжнародне, воєнно-політичне, військово-технічне, військове співробітництво, верифікаційна діяльність, центр, департамент.
Investigation of a Novel Interleaved Buck Converter for Renewable Energy Applications: Design and Analysis
Authors: Popuri Madhuchandra , Bhajana Veera Venkata Subrahmanya Kumar , Maharana Manoj Kumar
Published: June 2022

In this paper, a new interleaved buck converter with soft-switching is investigated. The soft-switching condition, zero voltage zero current switching (ZVZCS) of IGBTs during turn-on is obtained with the help of a soft-switching cell that includes active and passive devices that is incorporated in the interleaved buck converter (IBC). The presence of the soft-switching cell reduces the switching losses and improves the overall efficiency. The IGBTs in the converter achieved ZVZCS turn on operations, while converter is operated under both light and heavy loads. The principles of operation and theoretical aspects of the proposed converter system 400 V / 110 V / 2.5 kW are verified with simulation analysis.
Past and Future Practical Solutions for Torsional Vibration Damping in Vehicle Industry
Authors: Venczel Márk , Veress Árpád , Peredy Zoltán
Published: June 2022

In addition to material and production costs, consumption and emission limits, the requirements for performance, efficiency and space utilization must be met when it comes to the design of today's internal combustion engines for the automotive industry. As a result, three new design trends have been emerged (based on J. Pfleghaar and B. Lohmann's paper in 2013): 1. downsizing: reduction of engine size (number of pistons and stroke) for fuel and space-saving and CO2 emission reduction purposes, 2. downspeeding: reduction of engine speed to save fuel, which necessarily entails significantly higher torques being generated and transmitted in the engine, 3. turbo supercharging: increasing the pressure and compression ratio in the engine piston cylinder to cover the increased torque demand, which is accompanied by NOx gas emissions. Due to these new design trends, significant transverse, axial, and torsional oscillations can occur on the engine's crankshaft. To avoid power loss and fatigue due to the torsional oscillations, a torsional vibration damper is advised to be installed on the free end of the crankshaft or integrated into the flywheel. This review paper focuses on the possible reasons for torsional vibrations, the applied methods used to dampen them, and expected future trends.
Dining in the dark
Authors: Hoskins Toni
Published: June 2022

Our relationship to food and patterns of feeding creates opportunities for intimacy and meaningful communication. How we feed ourselves and others in families, couples, friendship groups, and the wider community reflects our social and cultural norms. Despite a growing interest in attachment theory and our relationship to food, research into the specific area of food, attachment, and sight loss remains scarce. It is estimated that more than two million individuals are living with sight loss in the UK. When people experience the life-changing event of losing their vision and acquiring a disability, their relationship with food impacts on their relationships with people. Equally, relationships with people impact on how those with sight loss relate to food, eating behaviours, and the sense of belonging to a wider community. These dynamics are explored in this article and illustrated with clinical examples.
The argument for attachment (as the cornerstone of the understanding of eating disorders)
Authors: Buckroyd Julia
Published: June 2022

Eating disorder symptoms, for all their painful behavioural constrictions, hold com-plex, personal stories of the sufferer’s relationship not only to food and her body, but also to the caregivers who fed or did not feed her—to the relational context in which needs were met or dismissed, and in which life came to feel as if it could or could not hold the potential for satisfaction, possibilities, and meaning (Petrucelli, 2015, p. 14). There is a wide consensus that eating disorders pose a significant puzzle for therapists. This article uses a case history to illustrate how an eating disorder can be addressed through the lens of attachment theory. Via the themes of trust and relationships, self-soothing, identity, self-esteem/body esteem, trauma, shame, and self-compassion, I will suggest how the eating disordered behaviour can be understood and how we, as therapists, might respond to it.
What does food have to do with it?
Authors: Chioni Konstantina
Published: June 2022

The eating disorder subgroups addressed by this article include, predominantly, anorexia nervosa, bulimia nervosa and binge-eating disorder. This article will reflect on how awareness of the attachment styles of patients across the subgroups of eating disorders helps to inform beneficial clinical decisions and the therapeutic process in general. Drawing from personal observations in therapy group settings as well as individual therapy sessions, this article discusses the similarities and differences between patients from the different subgroups regarding attachment styles, clinical presentation, features of the pathology and, especially, their recovery perceptions and aspirations. Often, patients of the different sub-groups envisage recovery in contrasting ways. Typically, anorexia nervosa patients aspire to free themselves from compulsive thinking and ritualistic behaviours but they remain acutely averse to changes to their physical appearance. Conversely, the bulimia nervosa and binge-eating patients, generally, wish to change their physical appearance but remain attached to established behaviours and lifestyle choices. The variances in the recovery approach across the subgroups will be discussed with regards to their underlying attachment styles.
On food, love, and loss
Authors: Samuel Jacqueline
Published: June 2022

In the aftermath of her wife’s death, the author reflects upon the impact of loss on her relationship with food. She touches on her history in which preparing and feeding nutritious and delicious food held a largely medicinal function and how that evolved in her early relationship with her wife. When her wife was diagnosed with cancer, paradoxically, food served at once as a symbol of agency and denial—sustenance to keep her wife alive—as well as a meter of cancer’s encroachment and the powerlessness to halt death. As the author grapples with her changing reality in the wake of death, she traces the integration of food, love, and loss into her new emerging post-bereavement identity.
Assessment of the configuration accuracy of two UWB local positioning systems, six antennae and 18 Hz vs. eight antennae and 33 Hz, to measure movement patterns in physical education
Authors: Rico-González Markel , Los Arcos Asier , Bastida-Castillo Alejandro , Pino-Ortega José
Published: June 2022

The use of valid, accurate and reliable systems is decisive for ensuring optimal data collection and correct interpretation of values. Among other factors, it seems that sampling rate and the number of nodes determine data accuracy using LPS. Thus, the aim of this study was to assess and compare the accuracy of two UWB configurations (i.e. UWB6_18HZ: 6 antennae and 18 Hz capacity vs. UWB8_33HZ: 8 antennae and 33 Hz capacity) to measure locomotion on court. A healthy and well-trained former soccer player (age: 38 years, mass: 76.34 kg, height 1.85 m) ran 9 m along the middle line of a volleyball court (n=10, samples= 424). UWB6_18HZ and UWB8_33HZ configurations have shown high accuracy in sport movement patterns monitoring (mean difference between actual measurements and UWB = 0.014±0.03m for UWB6_18HZ and 0.013±0.03m for UWB8_33HZ), although UWB8_33HZ presented higher accuracy (8.99±0.03 m) than UWB6_18HZ (8.94±0.03). Therefore, manufacturers should consider future developments based on sampling rates and number of antennae installed around the court.
Análise físico-química e microbiológica da água de poços artesianos em condomínios no município de Vitória da Conquista – BA
Authors: Barbosa Elian Chaves , Eça Marcela Almeida Curcino de , Portela Fernanda Santos , Santos Tayanne Andrade dos , Silva Rafaela Meira , Amorim Aline Teixeira
Published: June 2022

Com a crescente expansão urbana e o aumento do número de condomínios, uma alternativa de abastecimento mais econômica e sustentável, são os poços artesianos que podem fornecer uma água segura para o consumo. Porém essa água também está sujeita a contaminações por patógenos e podem sofrer alterações físico-químicas. O objetivo deste estudo foi analisar as características de potabilidade da água de poços artesianos em condomínios na cidade de Vitória da Conquista – Ba. Esta é uma pesquisa descritiva de caráter experimental exploratório, com abordagem quantitativa. A coleta das amostras de água dos poços artesianos se concentrou em cinco condomínios, escolhidos de forma aleatória. Foram analisados parâmetros físico-químicos como: pH, turbidez, condutividade, temperatura, alcalinidade total e alumínio. Nas amostras microbiológicas, foram avaliadas a presença de coliformes totais e termotolerantes, bem como as análises parasitológicas. Foi verificado que a água de todos os poços não atendeu aos padrões de potabilidade estabelecidos pela Portaria 888/2021, o que sugere a necessidade de um melhor controle destes poços.
Chronic Compensated Tonsillopharingitis: Clinical and Microbiological Features
Authors: Meloyan E. K. , Safronenko A. V. , Gantsgorn E. V. , Polyakova V. I. , Stagniev S. D. , Ilyina A. A. , Romanova E. Yu.
Published: June 2022

The article presents the results of a complex clinical and bacteriological study aimed at determining the quantitative and qualitative composition of the microflora of the pharyngeal lymphatic ring in patients with chronic compensated tonsillopharyngitis, including identification of microorganisms followed by determination of their sensitivity toward antibacterial and antimycotic drugs. β-hemolytic streptococcus was revealed to be the most etiologically significant microorganism in the development of chronic compensated tonsillopharyngitis. In addition, populations of microorganisms growing in the throat of such patients were found to exhibit high resistance toward antibacterial and antifungal drugs.
Great Powers, Core Members, and the Fate of Regional Cooperation: A Study of Indian and the US Behavior towards India-Pakistan-Iran Gas Pipeline Project
Authors: Naazer Manzoor Ahmad
Published: June 2022

This paper elucidates the significance of the role and behavior of a core member - occupying a central position and politically, militarily, and economically superior to others – and the outside great or superpower for the success of the process of regional cooperation especially in the developing world. The core state plays a vital role in either success or failure of any regional cooperative arrangement. Outside powers, especially the great or superpowers can also affect the fate of regional schemes. Moreover, the nature of relations between the core member state and an outside great or superpower also affects in diverse ways the process of regionalism. Under this theoretical framework, this paper investigates why the Iran-Pakistan-India gas pipeline proposal could not materialize. The paper explores internal and external factors that halted the progress of the project with special reference to the role and behavior of India and the United States. It illuminates how the Indo-US strategic partnership and nuclear deal overshadowed a crucial project that was designed to create interdependence between three states, especially India and Pakistan and establish peace in the region. The study finds that India emphasized its connections with the United States to realize its ambitions of becoming a key player in world affairs. The paper shows how the US distracted India from pursuing a crucial regional cooperation project by providing payoffs and incentives that jeopardized the process of regionalism in South Asia.
An Application to Keep in Mind in Cases of Pulmonary Thromboembolism: Positive Airway Pressure System
Authors: Kınık Oğulcan , Yenal Kadir , Ay Ahmet Emre , Erdem Ahmet Burak , Dönmez Safa , Büyük Faruk
Published: June 2022

Massive pulmonary embolism is a vital emergency pulmonary pathology. Early diagnosis and treatment approach reduce mortality. Thrombolytic applications play an important role in the treatment. However, complications of thrombolytic therapy put a serious strain on physicians. In this case series, we aimed to present the management of carbon dioxide retention with the EzPAP® device in two young massive embolism patients who were given thrombolytic therapy.

Our 26 and 36-year-old male patients applied to our emergency department with complaints of flank pain and syncope, respectively. Massive PTE was detected in PCTAs taken due to hypoxia and tachycardia in our patients. When carbon dioxide retention developed in patients who were decided to be given thrombolytic therapy, barotrauma, which could be caused by non-invasive mechanical ventilation, was withdrawn. And it was decided to apply EzPAP® to these patients. In both patients, hypoxia and carbon dioxide retention were treated in a short time without complications. Etiological investigations of the patients are continuing and they were discharged with convalescence.

Conclusion; While thrombolytic therapy provides rapid and positive results, it also includes serious life-threatening side effects such as bleeding. EzPAP® can be used as an alternative treatment method for thrombolytic-related bleeding that may develop in the face and respiratory tract due to barotrauma of non-invasive mechanical ventilation.
Membrane-free Electrocatalysis of CO2 to C2 on CuO/CeO2 Nanocomposites
Authors: Tian Yangming , Fei Xiang , Ning Hui , Wang Wenhang , Tan Xiaojie , Wang Xiaoshan , Ma Zhengguang , Guo Zhihao , Wu Mingbo
Published: June 2022

Carbon dioxide electroreduction (CO2RR) with renewable energy is of great significance to realize carbon neutralization. Traditional electrolysis devices usually need an ion exchange membrane to eliminate the interference of oxygen generated on the anode. Herein, the novel CuO/CeO2 composite was facilely prepared by anchoring small CuO nanoparticles on the surface of CeO2 nanocubes. In addition, CuO(002) crystal planes were induced to grow on CeO2(200), which was preferable for CO2 adsorption and C-C bond formation. As the catalyst in a membrane-free cell for CO2RR, the Cu+ was stabilized due to strong interactions between copper and ceria to resist the reduction of negative potentials and the oxidation of oxygen from the counter electrode. As a result, a high Faradaic efficiency of 62.2% toward C2 products (ethylene and ethanol) was achieved for the first time in the membrane-free conditions. This work may set off a new upsurge to drive the industrial application of CO2RR through membrane-free electrocatalysis.
Shifting Trade-offs: Finding the Sustainable Nexus of Hydropower and Environmental Flows in the San Joaquin River Watershed, California
Authors: Willis Ann D. , Rheinheimer David E. , Yarnell Sarah M. , Facincani Dourado Gustavo , Rallings Anna M. , Viers Joshua H.
Published: June 2022

Environmental flow management in watersheds with multi-objective reservoirs is often presented as an additional constraint to an already strained and over-allocated stream system. Nevertheless, environmental flow legislation and regulatory policies are increasingly being developed and implemented globally. In California, USA, recent legislative and regulatory policies place environmental flows at the forefront of the state’s water management objectives; however, the increased reliance on hydropower to support climate change mitigation goals may complicate efforts on both issues. This study modelled alternative environmental flow strategies in the major tributaries to the San Joaquin River in California. Strategies included detailed water management rules for hydropower production, flood control, and water deliveries, and three methodological approaches to environmental flow releases: minimum instream flows (“baseline”) year-round, 40% of full natural flow (FNF) during the spring runoff season and minimum releases the remainder of the year, and functional flows year-round. Results show that environmental flow strategies affect downstream flow releases in each of the San Joaquin’s four sub-basins differently depending on infrastructure capacity, water management objectives, and hydrologic year types. While hydropower production was comparable or declined in the Stanislaus, Tuolumne, and Merced basins, functional flow and 40% FNF strategies increased hydropower production in the Upper San Joaquin basin by 11%. Uncontrolled spill of high flow events decreased when high flow releases were based on hydrologic cues rather than exclusively on flood storage capacity. Water deliveries were reduced in all years regardless of environmental flow strategy. The 40% FNF and functional flow strategies both increased water released to the river relative to baseline, but in different ways. The functional flow strategy allocated water in a holistic approach that enhanced ecological functions in all years, but particularly in moderate and wet years. In contrast, the 40% FNF strategy provided increased flows relative to baseline and some ecological benefit in dry years, but less ecological benefit in other years. This study shows that alternative environmental flow strategies will have different and important trade-offs for integrated water management, and may mutually benefit seemingly conflicting objectives.
One Fee, Two Reductions: The Double Abatement Effect of Pollutant Discharge Fees on Industrial Pollution and Carbon Emissions
Authors: Wang Zhimeng , Yu Lu , Zheng Mengmeng , Xing Yafei , Liu Xiaoyuan , Wang Yanwen , Xiao Zumian
Published: June 2022

Formulating policies under the dual policy objectives of environmental protection and carbon neutrality in China is essential. This paper utilizes enterprise-level data to construct a panel model. Our empirical test indicates that increasing China’s pollutant discharge fee can effectively reduce industrial pollutants, including wastewater and exhaust gas. The empirical results indicate that in terms of enterprises, pollutant discharge fees can not only directly reduce carbon emissions but also indirectly by reducing coal assumption. This paper also constructs a threshold model of the carbon emission reduction effect of population size. It has been proved that when the population size does not exceed the threshold, the utility of the pollutant discharge fee is apparent. According to this study’s heterogeneity test, the carbon emission reduction effect of the pollutant discharge fee is more evident in large- and medium-sized enterprises and heavy pollution enterprises.
Relationship Between CNVs and Immune Cells Infiltration in Gastric Tumor Microenvironment
Authors: Li Fazhan , Wen Huijuan , Bukhari Ihtisham , Liu Bin , Guo Chenxu , Ren FeiFei , Tang Youcai , Mi Yang , Zheng Pengyuan
Published: June 2022

Gastric cancer (GC) is a highly fatal and common malignancy of the digestive system. Recent therapeutic advancements have significantly improved the clinical outcomes in GC, but due to the unavailability of suitable molecular targets, a large number of patients do not respond to the immune checkpoint inhibitors (ICI) therapy. To identify and validate potential therapeutic and prognostic targets of gastric cancer, we used the “inferCNV” R package for analyzing single-cell sequencing data (GSE112302) of GC and normal epithelial cells. First, by using LASSO, we screened genes that were highly correlated with copy number variations (CNVs). Therefrom, five gene signature (CPVL, DDC, GRTP1, ONECUT2, and PRSS21) was selected by cross-validating the prognosis and risk management with the GC RNA-seq data obtained from GEO and TCGA. Moreover, the correlation analyses between CNVs of these genes and immune cell infiltration in gastric cancer identified CPVL as a potential prognostic marker. Finally, CPVL showed high expression in gastric cancer samples and cell lines, then siRNA-mediated silencing of CPVL expression in gastric cancer cells showed significant proliferation arrest in MGC803 cells. Here, we conclude that CNVs are key regulators of the immune cells infiltration in gastric TME as well as cancer development, and CPVL could potentially be used as a prognostic and therapeutic marker in gastric cancer.
A Comprehensive Analysis of HAVCR1 as a Prognostic and Diagnostic Marker for Pan-Cancer
Authors: Liu Sheng , Tang Wenting , Cao Jing , Shang Mei , Sun Hengchang , Gong Jiao , Hu Bo
Published: June 2022

Hepatitis A virus cellular receptor (HAVCR1) is a type-1 integral membrane glycoprotein that plays a key role in immunity and renal regeneration and is abnormally expressed in various tumor types. Nonetheless, the function of HAVCR1 in pan-cancer remains unknown. In this study, we comprehensively analyzed the expression and promoter methylation level of HAVCR1 and assessed the immune cell infiltration, correlation between stromal and immune cell admixture, CD (Cluster of Differentiation) and HAVCR1 expression and prognostic value of HAVCR1 mRNA expression in Liver hepatocellular carcinoma (LIHC) and Pancreatic adenocarcinoma (PAAD). Our results showed that HAVCR1 was overexpressed while the promoter methylation of HAVCR1 was decreased in Liver hepatocellular carcinoma and Pancreatic adenocarcinoma. HAVCR1 was associated with increased infiltration of B cells, CD8 cells, macrophages, neutrophils and Dendritic cells in Liver hepatocellular carcinoma and Pancreatic adenocarcinoma. HAVCR1 expression was positively correlated with the immune, stromal and estimate scores of Pancreatic adenocarcinoma and the stromal and estimate scores of Liver hepatocellular carcinoma. Furthermore, HAVCR1 expression was correlated with other immune molecules such as HHLA2 (Human endogenous retrovirus-H long terminal repeat-associating protein 2), CD44 and TNFRSF4 (TNF Receptor Superfamily Member 4) in Liver hepatocellular carcinoma and Pancreatic adenocarcinoma. During Kaplan-Meier analysis, high HAVCR1 expression in Liver hepatocellular carcinoma and Pancreatic adenocarcinoma correlated with poor survival. A marginally significant p-value (p = 0.051) was obtained when the relationship between HAVCR1 expression in Liver hepatocellular carcinoma and prognosis was analyzed, attributed to the small sample size. Overall, we provided compelling evidence that HAVCR1 could be a prognostic and diagnostic marker for Liver hepatocellular carcinoma and Pancreatic adenocarcinoma.
Risk Model and Immune Signature of m7G-Related lncRNA Based on Lung Adenocarcinoma
Authors: Zhang Chuanhao , Zhou Dong , Wang Zhe , Ju Zaishuang , He Jiabei , Zhao Genghao , Wang Ruoyu
Published: June 2022

Lung cancer is a major cause of cancer-related deaths globally, with a dismal prognosis. N7-methylguanosine (m7G) is essential for the transcriptional phenotypic modification of messenger RNA (mRNA) and long noncoding RNA (lncRNA). However, research on m7G-related lncRNAs involved in lung adenocarcinoma (LUAD) regulation is still limited. Herein, we aim to establish a prognostic model of m7G-related lncRNAs and investigate their immune properties. Eight prognostic m7G-related lncRNAs were identified using univariate Cox analysis. Six m7G-related lncRNAs were identified using LASSO-Cox regression analysis to construct risk models, and all LUAD patients in The Cancer Genome Atlas (TCGA) cohort was divided into low-risk and high-risk subgroups. The accuracy of the model was verified by Kaplan-Meier analysis, time-dependent receiver operating characteristic, principal component analysis, independent prognostic analysis, nomogram, and calibration curve. Further studies were conducted on the gene set enrichment and disease ontology enrichment analyses. The gene set enrichment analysis (GSEA) revealed that the high-risk group enriched for cancer proliferation pathways, and the enrichment analysis of disease ontology (DO) revealed that lung disease was enriched, rationally explaining the superiority of the risk model. Finally, we found that the low-risk group had higher immune infiltration and checkpoint expression. It can be speculated that the low-risk group has a better effect on immunotherapy. Susceptibility to antitumor drugs in different risk subgroups was assessed, and it found that the high-risk group showed high sensitivity to first-line treatment drugs for non-small cell lung cancer. In conclusion, a risk model based on 6 m7G-related lncRNAs can not only predict the overall survival (OS) rate of LUAD patients but also guide individualized treatment for these patients.