bluuebunny/crossref_metadata_2025 huggingface dataset:
PARAFAC model as an innovative tool for monitoring natural organic matter removal in water treatment plants
Authors: Ndiweni Sikelelwa N. , Chys Michael , Chaukura Nhamo , Van Hulle Stijn W. H. , Nkambule Thabo T. I.
Published: April 2020

The increase of fluorescent natural organic matter (fNOM) fractions during drinking water treatment might lead to an increased coagulant dose and filter clogging, and can be a precursor for disinfection by-products. Consequently, efficient fNOM removal is essential, for which characterisation of fNOM fractions is crucial. This study aims to develop a robust monitoring tool for assessing fNOM fractions across water treatment processes. To achieve this, water samples were collected from six South African water treatment plants (WTPs) during winter and summer, and two plants in Belgium during spring. The removal of fNOM was monitored by assessing fluorescence excitation–emission matrices datasets using parallel factor analysis. The removal of fNOM during summer for South African WTPs was in the range 69–85%, and decreased to 42–64% in winter. In Belgian WTPs, fNOM removal was in the range 74–78%. Principal component analysis revealed a positive correlation between total fluorescence and total organic carbon (TOC). However, TOC had an insignificant contribution to the factors affecting fNOM removal. Overall, the study demonstrated the appearance of fNOM in the final chlorinated water, indicating that fNOM requires a customised monitoring technique.
Fronteras y representaciones fronterizas: aproximaciones comparativas entre Estados Unidos y América Latina
Authors: Cueva Perus Marcos
Published: April 2020

El artículo se propone realizar una aproximación comparativa entre las nociones de frontera y las representaciones fronterizas entre Estados Unidos y América Latina y el Caribe. Constata que el número de conflictos fronterizos en el mundo ha venido disminuyendo, que Estados Unidos concibe la frontera con un mito nacionalista que encarna la fe cuasi religiosa en el libre mercado y la democracia, y que el subcontinente americano, con fronteras más complejas que las estadounidenses, ha mostrado en este terreno una extraordinaria estabilidad desde hace décadas. El artículo alerta sobre los riesgos que pueden entrañar, al trasladarse a otros países, las representaciones fronterizas estadounidenses, que incluyen por otra parte la problemática de la segmentación multicultural. América Latina y el Caribe tienen fronteras estables, pero son vulnerables a las representaciones fronterizas provenientes del exterior. Palabras clave: frontera, Estados Unidos, América Latina, mitos, representaciones.
Migración e (in)tolerancia religiosa: aportes al estudio del impacto de la migración internacional en la percepción de la diversidad religiosa
Authors: Odgers Ortiz Olga
Published: April 2020

La confrontación con un espacio social diferente exige a los mexicanos que migran a los Estados Unidos la reelaboración de un sinnúmero de referentes de identidad, entre los que destacan las creencias y las prácticas religiosas. Diversos estudios han mostrado la forma en que, en algunas ocasiones, quienes migran recurren a prácticas de la religiosidad popular para crear puentes y mantener vínculos con las comunidades de origen, mientras que en otros casos, la experiencia migratoria favorece los procesos de conversión religiosa. En este trabajo se retoman tales experiencias para abordar una tercera expresión del impacto de la migración en el cambio religioso: se trata de la transformación de la idea de diversidad religiosa entre quienes migran, y por consiguiente de la modificación de algunas actitudes de tolerancia e intolerancia religiosa.
Dinámicas configuraciones étnicas y renovaciones culturales inéditas. El caso de la más reciente evangelización protestante entre los indígenas guambianos en Colombia
Authors: Demera V. Juan Diego
Published: April 2020

Este trabajo de investigación presenta y analiza los procesos de imposición, transferencia y mudanza de los preceptos misionales protestantes entre los indígenas guambianos de Colombia. Parte de la idea del cambio cultural para mostrar las dinámicas configuraciones de la etnicidad y la religiosidad guambianas, a través de la inclusión de los procesos de choque, localización y resistencia. A partir del análisis de narrativas orales y de la etnografía, el estudio contempla los elementos más significativos de la conversión religiosa, del cambio y la memoria ritual.
Participación ciudadana y gestión del agua: los líderes de Comités de Vecinos en Ciudad Juárez, Chihuahua
Authors: Córdova Bojórquez Gustavo
Published: April 2020

Se presenta el análisis de la participación ciudadana a través de los líderes de Comités de Vecinos (CV) en la gestión del agua en Ciudad Juárez, Chihuahua, aplicando una metodología en las que se manejan dos variables: las influencias externas e internas y 14 indicadores. Los resultados muestran que los CV constituyen una estructura de participación ciudadana que se encuentra en crisis. Presentan signos de desarticulación interna y externa. No existen mecanismos claros de convocatoria y participación dentro de su estructura, ni vías adecuadas de articulación de demandas con la autoridad gubernamental al permitir la participación de agentes externos de tipo político en los asuntos directivos y de funcionamiento de los mismos. Por tal motivo se duda de la capacidad de incursión de éstos en la toma de decisiones respecto al manejo del agua en la ciudad.
Eugenesia actual: un nuevo desafío para las disciplinas metacientíficas
Authors: O´Lery María de las Mercedes
Published: April 2020

Los parámetros con los que hasta el momento se distingue a las llamadas prácticas eugenésicas actuales de aquellas enmarcadas en la eugenesia clásica son: el carácter privado, individual y terapéutico de las primeras en contraposición al carácter colectivo, coercitivo y de perfeccionamiento de las segundas. Sin embargo, el debate ético actual en torno de las biotecnologías ha planteado sobre todo a partir de las críticas contra la llamada eugenesia liberal por parte de autores como Jürgen Habermas– la necesidad de considerar en un futuro a los tratamientos genéticos como objeto de redistribución a fin de evitar la discriminación que supondría la imposibilidad de acceso a los mismos. En el presente trabajo se intenta mostrar que dicha pretensión llevaría a la disolución futura de las características propias de la eugenesia actual que hoy permiten distinguirla de la clásica. En este sentido, se propone un análisis epistemológico de estas prácticas científicas actuales (o futuras) como uno de los caminos posibles en busca de redefinir parámetros que impidan identificar a las mismas con el fenómeno eugenésico del siglo pasado.
La alianza escuela-familia en los bordes de lo escolar en el gran Buenos Aires
Authors: López María Mercedes , Pérez Andrea Verónica
Published: April 2020

El presente trabajo, elaborado en el marco del proyecto “Análisis de experiencias alternativas en el abordaje del fracaso escolar masivo en el conurbano bonaerense”, toma como punto de partida dos categorías consideradas de relevancia para dar cuenta de la complejidad que caracteriza a las instituciones educativas públicas del conurbano de la Provincia de Buenos Aires en la actualidad. Se reflexiona en torno al concepto de frontera en el campo de las ciencias sociales, enfatizando su potencial para la comprensión de las prácticas que tienen lugar en la actualidad en las instituciones escolares. También se realiza una aproximación a la llamada alianza escuela-familia a fin de conocer y comprender algunas de las transformaciones que ha sufrido la misma durante las últimas décadas, en especial en los contextos estudiados, caracterizados por una grave situación de pobreza.
Klauzula antykonkurencyjna w prawie pracy. Praktyczne zastosowanie art. 300 k.p.
Authors: Pawłowska Aneta
Published: April 2020

Artykuł poświęcony jest dwóm powiązanym ze sobą zagadnieniom: złożonemu charakterowi umowy o zakazie konkurencji po ustaniu stosunku pracy oraz odpowiedniemu zastosowaniudo wskazanej wyżej umowy norm właściwych prawu cywilnemu znajdujących odpowiednie zastosowanie wskutek niewyczerpującego uregulowania rzeczonej umowy na grunciekodeksu pracy. W pierwszej kolejności autorka pokrótce omawia pojęcie oraz charakter wskazanego wyżej stosunku zobowiązaniowego. W szczególności, posiłkując się dotychczasowym dorobkiem doktryny oraz orzecznictwa, autorka poszukuje odpowiedzi na pytanie, czy umowa o zakazie konkurencji po ustaniu stosunku pracy winna być zakwalifikowana jako umowa cywilnoprawna, czy też może umowa z zakresu prawa pracy. W dalszej części dokładnie analizuje znaczenie oraz zakres zastosowania poszczególnych norm kodeksu cywilnego w prawie pracy. Dokonując szczegółowej charakterystyki kolejnych przesłanek zawartych w treści art. 300 k.p. autorka artykułu odpowiada, kiedy odpowiednie zastosowanie norm właściwych prawu cywilnemu jest możliwe w zakresie prawa pracy oraz na jakie ograniczenia należy w tym zakresie zwrócić uwagę. Ostatnia część artykułu poświęcona jest szerokiej analizietreści oraz istotnych elementów umowy o zakazie konkurencji po ustaniu stosunku pracy. Opisując zakres czasowy obowiązywania rzeczonej umowy, jej treść oraz ewentualnekonsekwencje jej niewykonania bądź nienależytego wykonania, autorka pracy pokazuje zjawisko przenikania się dwóch odmiennych gałęzi prawa, jak również praktyczne zastosowanie norm z zakresu prawa cywilnego w kodeksowej regulacji prawa pracy.
Nicotine Effects, Body Weight Concerns and Smoking: A Literature Review
Authors: Cepeda-Benito Antonio
Published: April 2020

How people become addicted to cigarette smoking and remain addicted despite repeated attempts to quit requires piecing together a rather complex puzzle. The present review contextualizes the role of nicotine and smoking sensory stimulation on maintaining smoking, describes nicotine’s effects on feeding behavior and body weight, and explores the impact of smoking outcome expectancies, including the belief that nicotine suppresses appetite and body weight, on the decision to smoke or vape (use of e-cigarettes). The analysis concludes with a review of rat models of human nicotine intake that attempt to isolate the effects of nicotine on appetite and weight gain. Animal research replicates with relative closeness phenomena observed in smokers, but the rat model falls short of replicating the long-term weight gain observed post-smoking cessation.
Regulatory T Cell Counts and Development of Malignancy in Patients with HIV Infection
Authors: Politou Marianna , Boti Sofia , Androutsakos Theodoros , Kontos Athanasios , Pouliakis Abraham , Kapsimali Violetta , Panayiotakopoulos George , Kordossis Theodore , Karakitsos Petros , Sipsas Nikolaos V.
Published: April 2020

Background:

T-regulatory cells (Tregs) play an important role in maintaining homeostasis
by attenuating the cytokine response to T-cell receptor (TCR) stimulation and by suppressing the
functioning of neighboring immune cells. In Human Immunodeficiency Virus (HIV) infection,
Tregs can be either beneficial, by suppressing generalized T-cell activation, or detrimental, by suppressing
protective anti-HIV cell-mediated immunity. An imbalance of Tregs and effector T-cells
can blunt immune responses to malignant cells or facilitate inflammation-mediated pathologies.

Objective:

The purpose of our study was to explore the possible correlation between Tregs’ concentration
and HIV infection’s parameters as well as the development of hematological and solid malignancies.

Methods:

In a longitudinal prospective study, ex vivo phenotyping of fresh peripheral blood mononuclear
cells from patients with primary HIV infection was performed at baseline. All patients were
then followed up every 3 months and the development of solid or hematological malignancies was
noted.

Results:

A total of 155 patients were included in the study and the median follow-up period was 64
months. Treg counts were significantly higher among males, patients with high viral load (>350
copies/ml) and patients with virological failure to antiretroviral treatment (ART). Linear regression
analysis showed a significant negative correlation between Treg levels and CD4 (+) T-cell counts.
Patients with neoplasia had lower levels of Tregs while increasing levels showed a negative correlation
with the development of neoplasia.

Conclusion:

In our population of HIV-infected patients, high levels of Tregs were associated with
disease progression, and low baseline levels were associated with a higher probability of developing
neoplasia.
Analysis of Nonsteroidal Anti-inflammatory Drugs by using Microfluidic Techniques: A Review
Authors: Fanali Chiara , D’Orazio Giovanni , Gentili Alessandra , Fanali Salvatore
Published: April 2020

In this review paper, miniaturized techniques, including both electromigration and liquid
chromatographic techniques, have been discussed considering their main features in the analytical field
for the separation and analysis of Nonsteroidal Anti-inflammatory Drugs (NSAIDs). In Capillary Electrophoresis
(CE) and nano-liquid chromatography (nano-LC), separation is performed in capillaries
with Internal Diameter (I.D.) lower than 100 μm and therefore flow rates in the range 100-1000 nL/min
are applied. Therefore, due to the low flow rate, high mass sensitivity can be obtained. Usually, conventional
UV detectors are used on-line; however, these techniques can be coupled with Mass Spectrometry
(MS). CE and nano-LC have also been applied to the separation of NSAIDs using silica stationary
phases (SP) modified with C18 promoting interaction with analytes mainly based on hydrophobic
interaction. Besides, the use of chiral SP was found to be effective for the chiral resolution of these
compounds. In addition to silica phases, monolithic (both organic and inorganic) material has also been
used. Although most of the presented studies aimed to demonstrate the usefulness of the considered
microfluidic techniques, some applications to real samples have also been reported.
Bortezomib – First Therapeutic Proteasome Inhibitor for Cancer Therapy: A Review of Patent Literature
Authors: Vora Pratik A. , Patel Rakesh , Dharamsi Abhay
Published: April 2020

Background:

Bortezomib is a reversible inhibitor of proteasome proteins in mammalian
cells. Bortezomib is proven to be cytotoxic to a number of tumor cells by disrupting their normal
homeostatic mechanism and thereby, causing cell death. Currently, Bortezomib is prescribed for patients
with multiple myeloma and mantle cell lymphoma.

Objective:

This assessment highlights the overview of the recent patents of Bortezomib. This review
includes patents grouped in sections like product patents, process patent, composition related
patents as well as the treatment methodology. The objective of this article is to facilitate researchers
with all existing patents at a single place.

Methods:

Data were searched from various online databases. In which, paid databases include
SciFinder® and Orbit®. Free databases include Patentscope® (WIPO), Worldwide Espacenet® (EPO),
Google Patents and InPASS (Indian patent database).

Results:

Several new processes and composition related patents of Bortezomib have been recently
patented as its orange-book listed patents are going to soon expire during July 2022. Further, due
to the problem of oxidation during development and long-term storage of Bortezomib formulation,
a number of excipients are tried in these patents to stabilize the same. However, there is still a need
for further development of an improved formulation of Bortezomib with better characteristics.

Conclusion:

Extensive research has been carried out on various processes for preparing Bortezomib
and the composition thereof. This type of dynamic research will clear the path for many
generic players in the United States, which lead to the reduction of the price of the composition and
thereby enhancing global health care at cheaper prices.
Recent Advances in Microwave Promoted C-P Cross-coupling Reactions
Authors: Ghosh Sujit , Biswas Kinkar , Basu Basudeb
Published: April 2020

:

Organophosphorous compounds are of potential importance in diverse fields. They are often
used as intermediates for making functionalized phosphine ligands as well as find vast applications
in the areas of industrial, agricultural and biological chemistry. The microwave-assisted synthesis
of C-P bonds has become increasingly popular because of its various advantages over conventional
heating in the perspectives of green chemistry.

:

This review article has primarily focused on the synthesis of various organophosphorous molecules
via microwave promoted C-P cross-coupling reactions under metal-catalyzed or metal–free conditions
over the last two decades. The synthesis of phosphine ligands on 4,4′-bisquinolone structural framework,
disubstituted phosphinic acid esters, vinyl phosphines, aryl- and vinylphosphonates, sugar and
nucleoside phosphonates, aminobisphosphonates, triphenyl phosphines, water-soluble tertiary phosphine
oxides and many other potentially useful organophosphorous compounds have been illustrated
critically. The Hirao reaction, Michaelis-Arbuzov reaction and Sandmeyer type of reactions are generally
involved in creating C-P bonds. The role of various metal catalysts, solvents, bases, additives
and temperature in different literatures are carefully discussed.
CLIMATE LITERACY AWARENESS AMONG PRESERVICE TEACHERS IN MALAYSIA
Authors: Nayan Nasir , Mahat Hanifah , Hashim Mohmadisa , Saleh Yazid , Norkhaidi Saiyidatina Balkhis
Published: April 2020

Climate change and global warming are the primary issues often debated when environmental issues are discussed nowadays. Among the efforts made to raise awareness concerning mitigation and adaptation to climate change is climate literacy acquired from the educational medium. Therefore, this article seeks to identify the level of awareness on climate literacy among preservice teachers in Malaysia. This study involved 500 final-year students from nine faculties at Sultan Idris Education University using the stratified sampling method. A questionnaire instrument was used to get feedback, containing four study variables, namely the knowledge, attitudes, skills, and practices of climate change mitigation and adaptation. The findings showed that the knowledge of and attitudes towards climate change mitigation and adaptation variables were at high levels, while the skills and practices of climate change mitigation and adaptation variables were at moderate levels. Thus, this indicates that students’ knowledge of and attitudes towards climate change mitigation and adaptation were good and satisfactory, but not the skills and practices of climate change mitigation and adaptation, which were still moderate and could be improved over time. The findings and issues that have been studied can be used as a reference and guide for universities, educators and ministries in improving students’ climate literacy, aiming for a more sustainable life.
CLASS CULTURE AND THE ACADEMIC STRESS OF DIGITAL NATIVES GENERATIONS
Authors: Muchsini Binti , Siswandari Siswandari
Published: April 2020

The culture Digital Natives Generations (DNG) are important considerations for lecturers in designing their courses because they are a generation that is very familiar with the technology. The DNG will feel pressured if the learning process is similar to that of the previous generation. Therefore, the purpose of this study is to examine the effect of cultural values in the classroom that may lead to the academic stress of DNG. The research uses quantitative research methods. The instruments of cultural values in the classroom refer to Hofstede's cultural dimension, while Academic Stress (AS) refers to Gadzella’s Student-Life Stress Inventory, with 152 respondents representing students at Sebelas Maret University Indonesia. Data analysis was performed using simple regression analysis with the aid of MINITAB. The results show that there are significant influence of cultural values in the classroom Power Distance (PD), collectivism individualism (CI), feminism masculinity (FM), uncertainty avoidance (UAI), and long-term orientation (LTO) on AS (p < 0.05). The results of the study could be utilized to determine the cultural values in the classroom that could be incorporated into the design of learning models so as to minimize the AS of DNG at higher education.
Developing a Questionnaire on Autistic Learning Environment
Authors: Ghazali Roslinda , Md Sakip Siti Rashidah , Samsuddin Ismail
Published: April 2020

Developing a new questionnaire as a tool used in data collection might be the greatest challenge.  The survey must be both valid and reliable.The purpose of the paper is to describe the processes undertaken to develop the questionnaire to measure awareness and knowledge among who involves in the autistic learning environment. The researcher refers to the expertise to check the quality of the tool. Each expert independently evaluated all details regarding the relevance, the clarity, and the understandability of the instrument. The overall content of the questionnaire comprises of sensory stimulation, sensory sensitivity, sensory design, and physical learning environment.  Keywords: Autism, pre-testing, questionnaire;eISSN: 2398-4287 © 2020. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer-review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.DOI: https://doi.org/10.21834/e-bpj.v5i13.1722
A vantagem do incumbente nas eleições municipais e estaduais brasileiras: Um estudo de 2000 a 2018
Authors: Araujo Jr Ari Francisco de , Pires Tiago Silva
Published: April 2020

Este estudo busca averiguar a existência da vantagem do incumbente em eleições municipais e estaduais brasileiras. A metodologia adotada é a de pares repetidos de Brambor e Ceneviva (2011), na qual pares de candidatos que se enfrentam mais de uma vez são a unidade de análise. A grande vantagem de se utilizá-la reside na retirada de efeitos fixos de candidato e município. Encontram-se evidências contrastantes em termos de vantagem do incumbente para eleições executivas de prefeitos e governadores. Estimou-se que prefeitos incumbentes sofrem uma desvantagem de 2,7 pontos percentuais nas eleições municipais brasileiras. Há evidências de queda na desvantagem do incumbente entre as eleições de 2000 e 2008. No entanto, observou-se um crescimento do fenômeno para os anos de 2012 e 2016. Por outro lado, governadores incumbentes gozam de uma expressiva vantagem de 9,5 pontos percentuais. A vantagem de governadores em exercício do cargo parece manter trajetória crescente de 1998 até 2010, quando atinge o máximo de 17,3 pontos percentuais.
Population-Level Interest and Telehealth Capacity of US Hospitals in Response to COVID-19: Cross-Sectional Analysis of Google Search and National Hospital Survey Data
Authors: Hong Young-Rock , Lawrence John , Williams Jr Dunc , Mainous III Arch
Published: April 2020

Background

As the novel coronavirus disease (COVID-19) is widely spreading across the United States, there is a concern about the overloading of the nation’s health care capacity. The expansion of telehealth services is expected to deliver timely care for the initial screening of symptomatic patients while minimizing exposure in health care facilities, to protect health care providers and other patients. However, it is currently unknown whether US hospitals have the telehealth capacity to meet the increasing demand and needs of patients during this pandemic.

Objective

We investigated the population-level internet search volume for telehealth (as a proxy of population interest and demand) with the number of new COVID-19 cases and the proportion of hospitals that adopted a telehealth system in all US states.

Methods

We used internet search volume data from Google Trends to measure population-level interest in telehealth and telemedicine between January 21, 2020 (when the first COVID-19 case was reported), and March 18, 2020. Data on COVID-19 cases in the United States were obtained from the Johns Hopkins Coronavirus Resources Center. We also used data from the 2018 American Hospital Association Annual Survey to estimate the proportion of hospitals that adopted telehealth (including telemedicine and electronic visits) and those with the capability of telemedicine intensive care unit (tele-ICU). Pearson correlation was used to examine the relations of population search volume for telehealth and telemedicine (composite score) with the cumulative numbers of COVID-19 cases in the United States during the study period and the proportion of hospitals with telehealth and tele-ICU capabilities.

Results

We found that US population–level interest in telehealth increased as the number of COVID-19 cases increased, with a strong correlation (r=0.948, P<.001). We observed a higher population-level interest in telehealth in the Northeast and West census region, whereas the proportion of hospitals that adopted telehealth was higher in the Midwest region. There was no significant association between population interest and the proportion of hospitals that adopted telehealth (r=0.055, P=.70) nor hospitals having tele-ICU capability (r=–0.073, P=.61).

Conclusions

As the number of COVID-19 cases increases, so does the US population’s interest in telehealth. However, the level of population interest did not correlate with the proportion of hospitals providing telehealth services in the United States, suggesting that increased population demand may not be met with the current telehealth capacity. Telecommunication infrastructures in US hospitals may lack the capability to address the ongoing health care needs of patients with other health conditions. More practical investment is needed to deploy the telehealth system rapidly against the impending patient surge.
Telemedicine for COVID-19 in China (Preprint)
Authors: Wang Yuye , Li Baojie , Liu Lei
Published: April 2020

UNSTRUCTURED

At present, COVID-19 has attracted the attention of the entire industry and society and the medical resources allocation process following COVID-19 outbreak is difficult. Telemedicine can eliminate the limitation caused by distance and provide high-quality expert services. It plays an important role in remote consultation, image transmission and information communication. In this viewpoint, we introduce how we use telemedicine to fight against pneumonia and explain the problems we found in our work in China. We hope to share our experience with the world and help other developing countries fight against the disease epidemic.
A Web- and App-Based Connected Care Solution for COVID-19 In- and Outpatient Care: Qualitative Study and Application Development (Preprint)
Authors: Schinköthe Timo , Gabri Mariano Rolando , Mitterer Manfred , Gouveia Pedro , Heinemann Volker , Harbeck Nadia , Subklewe Marion
Published: April 2020

BACKGROUND

From the perspective of health care professionals, coronavirus disease (COVID-19) brings many challenges as well as opportunities for digital health care. One challenge is that health care professionals are at high risk of infection themselves. Therefore, in-person visits need to be reduced to an absolute minimum. Connected care solutions, including telehealth, remote patient monitoring, and secure communications between clinicians and their patients, may rapidly become the first choice in such public health emergencies.

OBJECTIVE

The aim of the COVID-19 Caregiver Cockpit (C19CC) was to implement a free-of-charge, web- and app-based tool for patient assessment to assist health care professionals working in the COVID-19 environment.

METHODS

Physicians in Argentina, Germany, Iran, Italy, Portugal, Switzerland, and the United States explained their challenges with COVID-19 patient care through unstructured interviews. Based on the collected feedback, the first version of the C19CC was built. In the second round of interviews, the application was presented to physicians, and more feedback was obtained.

RESULTS

Physicians identified a number of different scenarios where telemedicine or connected care solutions could rapidly improve patient care. These scenarios included outpatient care, discharge management, remote tracking of patients with chronic diseases, as well as incorporating infected physicians under quarantine into telehealth services.

CONCLUSIONS

The C19CC is the result of an agile and iterative development process that complements the work of physicians. It aims to improve the care and safety of people who are infected by COVID-19.
Effect of humic acid on the growth and yield of two maize (Zea mays L.) cultivars on andisol
Authors: Prakoso Tangguh , Sulistyaningsih Endang , Purwanto Benito Heru
Published: April 2020

One way to improve maize (Zea mays L.) production is through land extension using Andisol land. However, andisol soil has phosphate (P) fixation problem due to the high amorphous material. Hence, the use of organic material in the form of humic acid that has greater affinity to amorphous minerals is recommended to solve the problem. This research was conducted in February-May 2017 at Tri Dharma field of Faculty of Agriculture, Gadjah Mada University. The Andisol land used has a low available P category from Datar, West Java and Wonosobo, Central Java. This research was arranged in a Randomized Complete Block Design (RCBD), consisting of 2 factors. The first factor was maize cultivar (Bisi-2 and Pioneer-35). The second factor was the doses of humic acid, consisting of control treatment (without fertilizer and humic acid), NPK without humic acid, and NPK + humic acid at 5%, 10%, and 15%. The percentage of humic acid given, based on the amount of NPK 16:16:16 fertilizer, was 350 kg ha-1. Fertilization was applied 3 times 100 kg ha-1 on 1 WAP, 150 kg ha-1 at 3 WAP and 100 kg ha-1 at 7 WAP. The results is, humic acid treatment had the same effect with NPK fertilization treatment only and control on P available Andisol soil. Humic acid, also has the same effect with NPK fertilizer treatment in increasing the yield component of 100 seeds weight, dry weight of seeds, harvest index, length of cobs and productivity.
ANALYTICAL METHODS FOR THE DETERMINATION OF AMINOGLYCOSIDES ANTIBIOTICS BY CHROMATROGRAPHIC TECHNIQUE
Authors: SOFIQUL ISLAM , V. MURUGAN , KUMARI PREMA
Published: April 2020

Aminoglycosides antibiotics are considered to be the antimicrobial agents used frequently in the treatment of human diseases caused by a bacterial infection. Most of the aminoglycosides antibiotics are highly polar in nature and they are lacking the UV absorbing chromophore in the molecules. The present articles accentuate the analytical method associated with the analysis of aminoglycosides molecules. Various chromatographic techniques like liquid chromatography, gas chromatography; mass spectrometry were used for the detection of aminoglycosides antibiotics. However, due to its limitation in the ultraviolet-visible spectrophotometry (UV/Vis) technique, different types of detection techniques like corona-charged aerosol detector (CAD), electrochemical detector (ECD) were used as a most powerful and versatile technique for the demonstration of these molecules in the analytical field. Analytical methods help to ensure the quality of the drug products. This review paper is devoted to providing an overview of the key performance technique used for the application and detection of these aminoglycosides molecules.
IMPROVING TRANSDERMAL DRUG DELIVERY SYSTEM FOR MEDROXYPROGESTERONE ACETATE BY OLIVE OIL AND DIMETHYLSULFOXIDE (DMSO) AS PENETRATION ENHANCERS: IN VITRO PENETRATION STUDY
Authors: MASRIJAL CAMELIA DWI PUTRI , HARMITA HARMITA , ISKANDARSYAH ISKANDARSYAH
Published: April 2020

Objective: Medroxyprogesterone Acetate (MPA) using a transdermal drug delivery system for contraception by passive diffusion is limited by the skin barrier properties. Penetration enhancers such as olive oil (fatty acid permeation enhancer) and DMSO (chemical enhancer) can be used. The objective of this study was to overcome MPA penetration problem by using olive oil and DMSO.

Methods: An in vitro penetration study using the Franz diffusion cells was performed. The first penetration study used MPA in olive oil (O) and MPA in coconut oil (C) with the concentration 100 μg/ml to each sample and MPA suspension as a control with the same concentration. The second study used MPA in olive oil with the concentration 200.0 μg/ml (A), MPA in olive oil with 0.5% DMSO with the concentration 200.0 μg/ml (B), and MPA in olive oil with 1% DMSO with the concentration 200 μg/ml (C).

Results: MPA penetration test for olive oil+0.5% DMSO had flux value 4.24±0.074 μg/cm2. hr and it was not significantly different (t-test, P>0.05) with olive oil+1% DMSO. While the MPA penetration test in only Olive oil had flux value 0.90±0.0087 μg/cm2. hr.

Conclusion: This research concluded that olive oil and 0.5% DMSO could improve the penetration of MPA into skin membrane by 4.5 times more than olive oil alone.
EVALUATION OF GLOMERULAR FILTRATION RATE ESTIMATING EQUATIONS IN CKD PATIENTS WITH DIABETES AND HYPERTENSION
Authors: PANEERSELVAM GANESH SRITHERAN , KASSAB YAMAN WALID
Published: April 2020

Objective: To compare the performance of Cockcroft-Gault and Modification of Diet in Renal Disease (MDRD) equations in estimating kidney function in CKD patients with diabetes and hypertension.

Methods: This study retrospectively reviewed medical records in Hospital Kajang. The GFR was calculated using Cockcroft-Gault and MDRD equations. Kappa Measure of Agreement was used to check the consistency of CKD staging. Wilcoxon signed-ranked tests and Bland-Altman plots were used to determine the difference of both equations. Spearman correlation was used to determine the correlation between blood pressure and blood sugar levels with eGFR.

Results: Data pertaining to a total of 81 patients were extracted. Results showed 22% of the patients were staged differently (Kappa value = 0.644 [P<0.001]) and the majority of them moved down one CKD stage when MDRD equation was used instead of Cockcroft-Gault equation. Wilcoxon signed rank test demonstrated there was a significant difference (P<0.001) in eGFR using CandG and MDRD in patients with diabetes and hypertension. Furthermore, the mean difference observed was 3.78±5.56 [P<0.001]), where the Cockcroft-Gault equation measured 3.78 units higher than MDRD equation. However, the relationship between blood sugar and blood pressure with eGFR were not significant.

Conclusion: There was a significant difference between Cockcroft-Gault and MDRD equations in estimating kidney function CKD patients with diabetes and hypertension.
Formación docente para integrar el eje medio ambiente en el proceso de enseñanza-aprendizaje en el nivel superior en la Universidad Autónoma de Guerrero México
Authors: Esteban Adriana Miranda , Solano Ramón Bedolla , Sampedro Rosas María Laura
Published: April 2020

Para atender la crisis ambiental planetaria, hacer conciencia en los seres humanos y tomar medidas que contribuyan a mejorar las condiciones del medio ambiente, es necesario recurrir a la Educación Ambiental (EA) para formar personas que actúen con responsabilidad ambiental y con una visión de sustentabilidad, una estrategia para implementar contenidos ambientales en el currículo es la transversalidad.En este documento se presenta una propuesta de formación docente con la finalidad de dar orientaciones para integrar de manera transversal en sus UAp contenidos ambientales, la metodología implementada fue mixta con un enfoque de investigación-acción. Previo a la implementación de formación docente se aplicó un diagnóstico de la percepción de los docentes sobre saberes ambientales se evidenció que la vinculación del eje medio ambiente con el perfil de egreso es escasa. En cuanto al proceso de formación docente se visualizó que los docentes contaban con conocimientos generales sobre el tema ambiental, pero no tenían claro como introducir estos contenidos en su unidad de aprendizaje. Se deben fortalecerse los trabajos colegiados, complementados con procesos de formación docente que permitan una adecuada implementación de la competencia ambiental en las unidades de aprendizaje, y que se refleje en el perfil de egreso.
Estado del arte sobre el impacto de deslizamientos de suelo y roca en puentes
Authors: Canales Alvarado Mario Alberto , Salazar Garrido José Antonio
Published: April 2020

En esta investigación se revisan las principales causas y mecanismos de colapso de puentes ante deslizamientos, principalmente de rocas y suelos. En el primer apartado, se contextualizan los deslizamientos en México; en el segundo, se describen los deslizamientos sobre estructuras tipo barreras flexibles y rígidas; en el tercero, se revisan y discuten los modos de colapso de algunos puentes estudiados. Por último, se propone una metodología para estudiar el impacto de deslizamientos de tierra y suelo sobre la superestructura de un puente. La finalidad de este trabajo es proporcionar información para comprender el fenómeno de impacto del deslizamiento de desecho de rocas y suelo sobre los puentes, así como facilitar el hallazgo de soluciones en el diseño de puentes, en investigaciones futuras, y la proyección de medidas de protección para puentes ya construidos, cercanos a laderas de cerros.
El daño al medio ambiente: entidad jurídica para la obligación de reparación
Authors: Roqué Fourcade Elsa Cristin
Published: April 2020

El tema forma parte de un proyecto cuyo objeto es el derecho de las energías. Este trabajo se aboca al concepto jurídico de daño ambiental desde la doctrina y normas del derecho ambiental; se propone un enfoque donde prevalezcan las personas y el derecho a un ambiente sano para el desarrollo, como los elementos propios que justifican un modo de ser de la responsabilidad por daños y de la reparación integral.
Más allá del quehacer jurisdiccional de la Suprema Corte de Justicia de la Nación
Authors: Flores Villicaña Quetziquel
Published: April 2020

La Constitución Política de los Estados Unidos Mexicanos (CPEUM), en el Artículo 49, establece el esquema de la división tripartita de gobiernos, delimitando las esferas de competencia de cada uno de los poderes que garantizan los pesos y contrapesos necesarios en cualquier democracia. En el presente trabajo no se analizarán las facultades jurisdiccionales típicas del Poder Judicial, sino las legislativas y administrativas de la Suprema Corte, dentro de las cuales se encontraba la facultad de investigación, cómo funcionó y en qué casos importantes se ejerció, la cual fue eliminada con la reforma constitucional del 10 de junio de 2011. Además, se revisará la facultad de la Suprema Corte de Justicia de la Nación de expedir acuerdos generales, fundamentalmente analizaremos los acuerdos 10/2000 y 5/2001 por el impacto que tiene en las funciones sustantivas de la Corte de Justicia de la Nación a decir el control de constitucionalidad.
Vivir y pensar la construcción de la sociedad anarquista desde la realidad mesoamericana, ayer y hoy
Authors: Maldonado Alvarado Benjamín
Published: April 2020

La vida comunal de los pueblos mesoamericanos ha sido la base de la resistencia indígena comunitaria frente al colonialismo español y luego frente al mexicano. Este modo de vida y de pensar fue considerado por los magonistas, en la década de 1910, como la poderosa experiencia histórica que sería la base para la reconstrucción libre de la sociedad mexicana, después del triunfo de la corriente anarquista de la revolución que impulsaban desde el exilio en Estados Unidos; pero no valoraron a la comunalidad como una forma de resistencia para liberarse del colonialismo capitalista, porque suponían muerto un modo de vida que hoy sigue vivo en comunidades de estados como Oaxaca.
La cultura mexicana en el siglo XX
Authors: Rosas Corona Mariana Itzél
Published: April 2020

¿Cómo progresaron las expresiones culturales en nuestro país a través del siglo XX y cuál fue su importancia en el desarrollo de México como nación? En el libro La cultura mexicana en el siglo XX (El Colegio de México, 2010), Carlos Monsiváis ofrece un breve y certero recorrido por la evolución de lo que conocemos como cultura mexicana, durante el siglo XX. Muestra las principales corrientes originadas a partir de los diversos movimientos sociales, políticos y económicos, que más influyeron en la cultura y en el desarrollo de la sociedad mexicana.

Monsiváis nos habla del impulso del modernismo, bajo la premisa de que la cultura acabaría con la barbarie a la que el pueblo estaba sometido, transitando por el positivismo, el cual influyó en la construcción de la nación y la comprensión de la nacionalidad.
Project-based learning model assisted by worksheet: It’s effect on students’ creativity and learning outcomes
Authors: Suwarno S. , Wahidin W. , Nur Sofyan Hasanudin
Published: April 2020

The low factor of learning outcomes is triggering by the emergence of students' boredom in learning. This study aimed to determine the effect of Project-Based Learning (PjBL) Models assisted by the Science Worksheet on Applied Waste Management on students' creativity and learning outcomes. This research was a quasi-experimental study. The population was all students in Vocational High School 1 Cikedung, Indonesia, and the sample was 57 students from two classes. Learning outcomes data obtained through tests with multiple-choice questions while creativity data using response questionnaires. The data obtained were analyzed using a one-way analysis of covariance. The results showed there was a significant effect of the learning model on students' creativity and learning outcomes. It concluded that the PBL model assisted in the worksheet has a positive impact on student competencies, especially on their creativity and biology learning outcomes.
The correlation between learning styles and biology learning performance of Nigerian students
Authors: Abidoye Florence Omosholape , Olorundare Adekunle Solomon
Published: April 2020

Learning style has been considered as one of determining factors for learning processes. This study aimed at observing the correlation between students’ learning style and performance of Nigerian students in biology. The sample of this study consisted of 100 students which were randomly selected from the secondary schools in Ifelodun LGA, Kwara State, Nigeria. The two validated instrument used for data collection were Grasha & Reichmann’s Student Learning Scale and VAK/VARK Learning Style. The data gained were analyzed using percentage, Pearson correlation, and Chi-Square test. The study findings indicated that: (i) there was a negative correlation between students’ academic performance and visual (-0.061) and kinesthetic learning style (-0.50), as well as positive correlation between the performance and auditory learning style (0.108). (ii) There were no significant differences between the study of learning styles, either visual (t(99) = 1.60, p = 0.11), auditory (t(99) = 1.33, p = 0.18), or kinesthetic (t(99) = 0.59, p = 0.55), of male and female biology students’ performance. Thus, it is suggested that teachers choose the most proper learning methods which accommodate the students’ need based on their learning styles.
Conflicts in Bayesian Statistics Between Inference Based on Credible Intervals and Bayes Factors
Authors: Lovric Miodrag M.
Published: April 2020

In frequentist statistics, point-null hypothesis testing based on significance tests and confidence intervals are harmonious procedures and lead to the same conclusion. This is not the case in the domain of the Bayesian framework. An inference made about the point-null hypothesis using Bayes factor may lead to an opposite conclusion if it is based on the Bayesian credible interval. Bayesian suggestions to test point-nulls using credible intervals are misleading and should be dismissed. A null hypothesized value may be outside a credible interval but supported by Bayes factor (a Type I conflict), or contrariwise, the null value may be inside a credible interval but not supported by the Bayes factor (Type II conflict). Two computer programs in R have been developed that confirm the existence of a countable infinite number of cases, for which Bayes credible intervals are not compatible with Bayesian hypothesis testing.
Análisis del comportamiento de las acciones de crecimiento y de valor en el mercado financiero
Authors: Venegas Venegas Maria Pia
Published: April 2020

El presente artículo tiene por objeto analizar el comportamiento de los indicadores de las acciones de valor y de crecimiento en el mercado financiero por un período de 3 años (2009-2011). Explicando la creación de los índices de las acciones de crecimiento y valor, el crecimiento obtenido por las empresas de acciones de crecimiento y valor, así como la comparación de las acciones de valor y crecimiento, en base a los resultados de las empresas. Concluyendo que el consejo entregado por los expertos en cuanto a invertir en época de contingencia económica, en acciones de valor y no de crecimiento es un modo de no arriesgarse a la volatilidad que presentan las acciones, esto porque las acciones de valor tienen un comportamiento más estable que las empresas querepresentan las acciones de crecimiento, ya que éstas últimas alcanzaron su crecimiento y reconocimiento, adicionalmente, forman parte del IPSA. En el período de estudio, es más rentable invertir en acciones que están indexadas a este índice.
Análisis a los procesos estratégicos en relación al marco regulatorio de gobierno corporativo
Authors: Mena Meza Paola Andrea
Published: April 2020

Con la presente investigación se analiza la teoría en normativa referente a gobierno corporativo basándose en los principios de la Organización para la Cooperación y el Desarrollo Económico (OCDE) relacionándolos así, con los procedimientos estratégicos al momento de la formulación en una organización, su respectiva implantación, posteriormente, la evaluación de los mismos. Esto, se realizó a través de entrevistas a personas que trabajen en una empresa, la cual tenga incorporado en ella un gobierno corporativo; se analizarán los resultados obtenidos de la entrevista, se compararán en efecto con la teoría que fundamenta el problema de investigación y verificando la consideración de los procedimientos estratégicos a buenas prácticas de gobierno
David E. Nye's 'Image Worlds' - Corporate Identities at General Electric. 1890- 1930
Authors: Lundén Rolf
Published: April 2020

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Tom Moylan's 'Demand the Impossible
Authors: Thomsen Christen Kold
Published: April 2020

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AS FORÇAS DO FIGURAL OU ALGUMAS CATEGORIAS DE ANÁLISE PARA DRAMATURGIAS MODERNAS E CONTEMPORÂNEAS
Authors: Brito Nayara Macedo Barbosa de
Published: April 2020

A personagem dramática, conforme forjada pela tra- dição aristotélico-hegeliana, enfrentou um processo de decomposição e posterior recomposição, sob no- vas bases e nomenclaturas, ao longo do século XX. Nesse sentido, propomo-nos a investigar a pertinên- cia da concepção de figura desenvolvida por Gilles Deleuze (1981) a partir da análise da obra do pintor anglo-irlandês Francis Bacon e enquanto desenvol- vimento teórico da noção homônima elaborada por Jean-François Lyotard (1979) para a análise de um recorte das dramaturgias moderna e contemporâ- nea. Para tanto, realizamos o cotejamento de alguns exemplos dessas dramaturgias e suas concretiza- ções cênicas com as pinturas baconeanas, organi- zando nossa discussão a partir de algumas catego- rias analíticas levantadas por Deleuze em seu estudo. Palavras-chave Figura. Figural. Dramaturgia Moderna. Dramaturgia Contemporânea. Francis Bacon.
UBU REI: UMA PARTICIPAÇÃO LATINO-AMERICANA NA PQ19
Authors: Almeida Desirée Bastos de
Published: April 2020

Este artigo pretende descrever o processo de criação, desenvolvimento e viabilização do projeto UBU REI, único projeto latino-americano apresentado na mostra Common Design Project da seção PQStudio da Quadrienal de Praga de 2019. O projeto foi criado por Igor Avelino e Rafael Torres, estudantes da Escola de Belas Artes da Universidade Federal do Rio de Janeiro, orientados orientado pela Profa. Desirée Bastos. Palavras-chave PQ2019. Common Design Project. Ubu Rei.