bluuebunny/crossref_metadata_2025 huggingface dataset:
Frequency of chronic Hepatitis B and Hepatitis C seropositivity in haemodialysis patients; A single center study.
Authors: Asma Naveed  , Muhammad Irfan Khattak  , Muhammad Owais Ismail  , Samina Naseem Khattak  , Sadia Rehman  , Irum Saddiqa
Published: October 2022

Objectives: To study the spectrum of chronic hepatitis in haemodialysis patients. Study Design:  Cross Sectional study. Setting: Kutiyanana Memon Hospital (KMH), A Tertiary Care, Charity Hospital at Karachi, Pakistan. Period: Jun 2015 to May 2020. Material & Methods: During the study period, 87 patients were followed up on and tested for hepatitis B and C virus infection. The patients were included in the study after calculation of sample size and application of inclusion and exclusion criteria. AxSYM, an enzyme-linked immunosorbent assay (ELISA)-based fast immunochromatographic technology, was used to screen the samples (Abbott Laboratories, Abbot Park, IL, USA). Hepatitis B and C prevalence was established, as well as the frequency of different sequelae such cirrhosis, encephalopathy, and hepatocellular cancer. Results: Our sample population was almost evenly split between males and females, with 44 (51%) males and 43 (59%) females. Three of the 43 females tested positive for HBV, whereas 19 (63 %) tested positive for HCV. On the other hand, in males, 11 (37 %) had chronic HCV and 9 (75 %) had Chronic HBV infection, accounting for 34% of the total HBV population. Conclusion: In haemodialysis patients, hepatitis B and C are very common. They are adding to morbidity and mortality of already suffering community. This trend is surrogate marker of suboptimal infection control techniques during dialysis in underdeveloped countries like Pakistan. To protect an already afflicted community from a potentially preventable disease, immediate measures are required for prevention and early diagnosis of chronic hepatitis.
Effects of cervical traction mobilization with mulligan’s SNAGS on Pain, cardiovascular and respiratory outcomes among young adults with cervical pain.
Authors: Zoya Mehmood  , Umama Ijaz  , Iqra Imtiaz  , Asmar Fatima  , Muhammad Junaid Akram  , Naveed Ahmed  , Ibraheem Zafar
Published: October 2022

Objective: To determine the effect of Mulligan’s Cervical Sustained natural Apophyseal glide and cervical traction cardiovascular and respiratory outcomes; systolic blood pressure, diastolic blood pressure, heart rate, ventilation rate, oxygen saturation, neck disability index and cervical range of motion. Study Design: Randomized Control Trial. Setting: Shifa Tameer-e-Millat University, Islamabad Pakistan. Period: November 2021 to March 2022. Material & Methods: A total of 84 participants with age range of 18 to 24 years of either gender with cervical pain and hypo mobility were included in the study whereas individuals with history of cervical trauma or injury, any structural deformity, vertebral instability, cardiac and respiratory complications were excluded. These participants were randomly allocated into two groups by using toss and trial method. Experimental group received sustained natural apophyseal glide and traction while the control group was subjected to traction alone. A total of four sessions were provided over a course of four weeks, with two weeks interval between them. Pre and post vitals including blood pressure, heart rate, respiratory rate and oxygen saturation were monitored at each session along with Numeric Pain Rating scale, Neck disability index and cervical range of motion. Results: Mean age of the participants was 21.70±2 years. Both groups showed significant reduction in pain with p value< 0.05 whereas heart rate was significantly increased in experimental group with pre median 81.75(16.6) and post median 82.00(15.05). Flexion range of motion was significantly improved in experimental group with pre median 69.00(15) and post median 71.00(11.7). Cervical left side bending was significantly improved with p value 0.04. Other variables including ventilation rate, oxygen saturation, systolic and diastolic blood pressure, Neck Disability Index, and other cervical range of motion showed no statistically significant difference with p value >0.05. Conclusion: The study results show improvement in both groups in terms of cardiovascular and respiratory outcomes but experimental group has more significant reduction in pain and change in pulse rate.
Aetiology and antibiotic susceptibility pattern of bacterial pathogens in respiratory specimens of COVID-19 patients on respiratory support: A tertiary care hospital study.
Authors: Shafqat Husnain Khan  , Muhammad Abid  , Asad Ahmed  , Anam Tariq  , Ayesha Bashir  , Chahat Hussain
Published: October 2022

Objective: To describe aetiology and antibiotic susceptibility pattern of bacterial pathogens in respiratory specimens of covid-19 patients on respiratory support in tertiary care hospital of Lahore. Study Design: Descriptive study. Setting: Microbiology Department, CMH, Lahore. Period: May 2021 to October 2021. Material & Methods: A total 107 isolates from 145 patients who were COVID-19 positive and on respiratory support were included in the study. Bacterial isolates were isolated from clinical samples according to standard protocol of culturing and incubation. Antibiotic sensitivity, carbapenamase detection was done according to CLSI 2021. Molecular identification of carbapenem resistant genes blaIMP and blaVIM was determined by PCR. Results: A total of 107 bacterial isolates were isolated from clinical specimens. A. baumannii was the most common isolated organism. Colistin and aminoglycosides were found to be the most effective antibiotics. Among carbapenem resistant isolates 89.5% were MHT positive and among these 59 (86.8%) were MBL positive. Among MBL positive isolates, 5.61% and 29.91% were positive for blaIMP and blaVIM respectively. Conclusion: Patients admitted for COVID-19 treatment are at higher risk of acquisition of secondary bacterial infections and antibiotic resistance among such pathogens is at alarming.
Ketofol as induction agent in diabetic patients.
Authors: Aslam Samina  , Ahmad Humaira  , Hussain Muhammad  , Muhammad Rauf
Published: October 2022

Objective: To evaluate the role of ketofol as induction agent in diabetic patients. Study Design: Randomized Control Trial. Setting: Department of Anesthesia, Abwa Medical College, Faisalabad. Period: 01-12-21 to 01-05-22. Material & Methods: Patients after informed consent divided randomly into two groups 25 in each. Group A receiving propofol 1.5 mg/kg and Group B receiving ketofol 1:2 as induction agent. The dose given was 1ml for every 5Kg. Standard 5 parameter monitoring with pulse oximetry, ECG, non invasive BP done starting from preoperative to 2 minutes, 5 minutes and 10 minutes after induction agent given. MAP and HR were monitored. Hemodynamic instability was defined as I) Heart rate >160/min or <50/min. II) MAP>120mmHg or <60 mm Hg. Results: Total 50 patients included in this study. 25 in each group. The results show significant stability in hemodynamics in group B. Conclusion: Ketofol has better hemodynamic stability as induction agent in diabetic patients when used in a 2:1 ratio. This makes it a good choice for this specific patient population.
Solitary rectal ulcer syndrome: Role of hydrocortisone enema in pediatric patients.
Authors: Ali Hammad  , Muhammad Tariq Aziz  , Ghazi Khan Khosa  , Muhammad Aslam Sheikh
Published: October 2022

Objective: To evaluate the effectiveness of adding hydrocortisone enema in the traditional management of Solitary rectal ulcers (SRU) in pediatric patients. Study Design: Randomized Controlled Trial. Setting: Department of Pediatric Gastroenterology, Children’s Hospital and The Institute of Child’s Heath, Multan, Pakistan. Period: January, 2021 till December, 2021. Material & Methods: A total of 52 children (15 years or younger) diagnosed to have SRU were included. Demographic data, clinical and colonoscopic findings were collected. Children were randomly divided into two groups. Group-A received only conventional therapy while Group-B received hydrocortisone enema in addition to conventional therapy. After starting treatment, patients were followed up every 15 days up to duration of 6 months and response to the treatment in terms of complete resolution of symptoms was noted. Results: The Mean age of 52 children was 9 + 1.8 years. Twenty eight (53.8%) were boys. The mean duration of symptoms was 5 + 1.4 months. Most common presenting features were per-rectal bleed 48 (92.3%) and mucus in stool 27 (51.9%). It was found that 14/25 (56.0%) children in Group-A reported complete resolution of symptoms in comparison to 20/24 (83.3%) in Group-B (p=0.0380) at 2-months post treatment follow up. Forty one children completed the 6-months follow up period and included in the final analysis. It was found that 10/21 (47.6%) children reported completed resolution of symptoms while Group-B, 18/20 (90.0%) children had complete resolution of symptoms (p=0.0036) at 6-months follow up. Conclusion: In children with SRUS, hydrocortisone enemas along with conventional treatment were found to be significantly more useful in resolution of pretreatment symptoms in comparison to conventional treatment alone. Further studies involving large sets of population are needed to verify the findings of present study.
MANEJO INICIAL DO PACIENTE COM DELIRIUM: UMA REVISÃO DE LITERATURA
Authors: Heinzen Rosângela Silva , Soares Diego , Almeida Igor Antônio De Macêdo , Fares Khadyja Vythoria W de O , Manzoli Isabela Reis , Zanatta Enzo Henrique Oliveira , Domingues Lohraine Talia , reis Gabriele Pereira dos , Bezerra Rodolfo Pereira , Callegari Sabrina Teixeira
Published: October 2022

Introdução: O delirium é caracterizado como um transtorno psíquico de início agudo e curso flutuante, com diminuição da consciência, déficit de atenção e alterações psicomotoras. Ademais, sabe-se que
Investigation of Characterization of Zerodur Glass Ceramics Used in Aerospace to Predict the Relationship between Surface Roughness and Subsurface Damage
Authors: ÖTENKAYA Şaban , ÜNAL Rahmi
Published: October 2022

Due to the brittle nature of the optical parts used in the grinding process to obtain a good surface quality, surface roughness and subsurface damage occur after the machining. These subsurface damages must be detected and destroyed with the help of post-process processes such as polishing. Because detecting these damages is time-consuming and costly, many researchers have tried relationship between subsurface damage and surface roughness since it is easier to detect and measure. In this study, Zerodur glass ceramic material characterization tests were carried out to predict the surface roughness and damage under the surface, and the material properties were determined to be specific to the sample. The grinding parameters taken from the previous studies and the values given for surface roughness and subsurface damage were examined with the help of the Lambropoulos theoretical model. The results theoretically showed that with the characterization of material properties different from those given in the literature, even if the parameters used in the experimental study do not change, much more severe subsurface damage will be created on the sample, and the load value applied to the material will increase significantly. For this reason, it is crucial to determine the material's mechanical properties by performing characterization tests before all material grinding and post-processing processes.
The effect of microwave energy on sintering of an austenitic stainless steel reinforced with boron carbide
Authors: Das Neves Ederson Bitencourt , Pollnow Edilson Nunes , Osorio Alice Goní§alves
Published: October 2022

Microwave heating has emerged as an alternative to traditional sintering methods because it consumes less energy and requires shorter processing times. The use of microwave energy in the processing of austenitic stainless steel AISI 316L reinforced with dispersed boron carbide particles was investigated in this study. Different processing parameters were used to investigate the effect of sintering time and temperature, as well as the weight percentage of the ceramic added to the steel matrix, on the final material properties. The compressibility curve, elastic relaxation, and geometric density of green compacts were used to investigate their physical properties. The Archimedes method was used to determine density, and the statistical treatment of analysis of variance was used to determine porosity. Images obtained using optical microscopy and scanning electron microscopy revealed the formation of a second phase in different volumes. The results showed that 1100 °C and a 15-minute plateau were sufficient to sinter the material. AISI 316L samples containing 3 wt.% boron carbide demonstrated greater volumetric formation of secondary phases, resulting in a significant increase in the hardness of the austenitic composite developed.
Effect of thermal aging above the glass transition temperature on the mechanical properties of rigid PVC tube
Authors: Hadj Amar Zineb , Chabira Salem Fouad , Sebaa Mohamed
Published: October 2022

Thermal aging of standard samples of rigid PVC (u-PVC) taken from plastic tubes near and above the glass transition temperature (Tg) was used to investigate the effect of elevated temperatures on the mechanical properties of rigid (u-PVC) tubes used in industrial areas. Three aging protocols were used, each lasting 90 days at 80 °C, 100 °C, and 120 °C. Crosslinking and chain scission reactions changed the tensile properties, either increasing them or decreasing them. For all three aging protocols, it was discovered that Young's modulus increased with aging time. Furthermore, the rate of increase of the modulus was observed to increase with aging temperature. The Yield stress showed the same pattern. Their increase in both cases is due to material stiffening caused by a crosslinking process. This last one was revealed by DSC, where Tg increased as a result of the chemical process. The decrease in elongation at break, which occurred progressively in all aging protocols and more precisely at temperatures above Tg, on the other hand, demonstrated the relationship between chain scissions and temperature. The material becomes more brittle as the temperature rises. Brittleness is caused by a high activity of chain scissions on the surface sample, which allows micro-cracks to form. When subjected to tensile forces, cracks propagate from the surface toward the sample's thickness.
Failure analysis of fractured dental implants
Authors: Bansal Rajesh , Sharma Amit Raj , Singh Vakil Singh
Published: October 2022

The success and predictability of titanium implants over long periods of time are well established, and there has been a tremendous increase in implant popularity among patients and clinicians over the last four decades. However, complications can occur, resulting in the loss of both the implant and the prosthesis. Dental implant fracture is uncommon; however, implants or abutment screws can fracture and cause significant problems for both the clinician and the patient. Improper design, overload, fatigue, and corrosion are all potential causes of implant fracture. Six retrieved fractured dental implants of varying diameter and thread design were collected on a regular basis to characterize their fracture behavior by SEM and assess the fracture mechanism. The majority of the implants were fractured as a result of fatigue crack initiation and propagation from the thread roots.
Deformation behavior and processing map of ATI 425 with initial lamellar microstructure
Authors: Mahdavi Rashid , Emadoddin E. , Abbasi S. M.
Published: October 2022

The effect of hot compression temperatures and strain rates on deformation behavior and resultant microstructure of ATI 425 alloy with initial lamellar microstructure was investigated in this study. The temperature and strain rate of the hot compression test were chosen to be in the 700-1100 °C and 0.001-1 s-1 ranges, respectively. The stress-strain curve and microstructure evaluation show that the alloy's flow softening is associated with globularization and dynamic recrystallization mechanisms. The constitutive equation calculates the activation energy for the α/β and β regions to be 348 kJ/mol and 201 kJ/mol, respectively. Dynamic recovery and partial recrystallization are the dominant structure modification mechanisms in the beta single-phase region. Bending and fragmentation of alpha plates is the dominant mechanism of microstructure promotion in the α/β region at low temperatures and low strain rates, less than 0.1s-1. Local shear and alpha plate break-up are the main factors in structural modification at high strain rates, greater than 0.1s-1. The extracted process map at 0.5 strain revealed three zones: instability, safe zone, and peak zone, with power dissipation efficiencies of 0 -0.25%, 30-40%, and above 40%.
Optimization and analysis of dry sliding wear behaviour of N-B4C/MOS2 unreinforced AA2219 nano hybrid composites using response surface methodology
Authors: Chitwadgi Riddhisha , Siddesh B , Shankar B Latha , Suresh R , Siddeshkumar N. G
Published: October 2022

The effect of heat treatment on nano-size B4C particle reinforced hybrid composites is discussed in this paper. For this, hybrid reinforced AA2219 composites with 2% by weight nano B4C and 2% by weight MoS2 particulates were fabricated using a two-stage stir casting process, and the specimens were heat treated to assess their influence on wear behavior. Experiments were carried out to study the wear behavior by varying important factors such as aging temperature, load, and sliding distance. Response Surface Methodology (RSM) designed by Box-Behnken was used to identify the critical variables influencing wear rate and optimize wear behavior. To comprehend the wear mechanisms involved, an analysis of the worn surface was presented. Based on the analysis, a regression equation with a predictability of 97.2% was developed for the response to obtain the optimum wear rate. The following order effectively captures the relative importance of the various factors determining the alloy's wear resistance: sliding distance, load, and aging temperature. When compared to load and sliding distance, heat treatments via artificial aging in the temperature range of 200-240 °C have no significant effect on the wear resistance of hybrid AA2219 composites reinforced with n-B4C and MoS2 particulates. However, when a temperature range of 200-240 °C is considered, composites exhibit better wear resistance at the aging temperature of 240 °C with ice quenching.
An investigation on dry sliding wear behavior of aluminum based metal matrix composites using grey relational analysis coupled with principle component analysis
Authors: P Muthu
Published: October 2022

The current study reports on wear properties of aluminum 6061-T6 reinforced with titanium carbide and graphite hybrid metal matrix composite using principal component analysis based grey relational analysis. Experiments were carried out using Taguchi's L9 orthogonal array. The dry sliding wear properties of composite samples are evaluated using a Pin-on-Disc apparatus. The effects of wear parameter input variables such as load, sliding speed, and sliding distance on different output responses, namely wear rate, friction force, and coefficient of friction, were investigated in this work. Using grey relational analysis in conjunction with principal component analysis, three output responses from each experiment were normalized into a weighted grey relational grade. According to the analysis of variance, the most influential parameter is sliding velocity (45.51%), followed by load (26.75%) and sliding distance (2.94%), all of which contribute to the quality characteristics. Additional experiments have confirmed optimal results. Finally, a scanning electron microscopic analysis was performed to investigate the wear mechanism.
Utah Dialect Regions and Features
Authors: Eddington David Ellingson
Published: October 2022

Data from the Utah Dialect Survey were used to delineate dialect boundaries in the state of Utah. Statistical algorithms divided the state into rural and urban dialect zones. Twelve features were identified that distinguish the two dialects. Three additional features were extracted from the the Harvard Survey of North American Dialects. The idea that the rural vs. urban divide is related to a greater number of immigrants to urban areas is discounted. Many rural features coincide with those used more by older Utahns suggesting that rural areas maintain more conservative Utah characteristics.
Renal histopathology after mixed liquor consumption in Wistar rat
Authors: Narendra Lintang Yudhisthira  , Anny Setijo Rahaju  , Arifa Mustika
Published: October 2022

In Indonesia illegal traditional liquor mostly contain ethanol and methanol some of illegal liquor Indonesia called cukrik (mixed liquor), Misuse of mixed liquor can lead to intoxication and may lead to death. Several studies have shown its effect on kidney damage. This study is to analyzing the effect of mixed liquor (ethanol and methanol) on the histopathological damage of male Wistar rat kidney. This was experimental laboratories using a post-test only control group design. We are using 28 wistar rats that were divided into four groups, each group consisting of 7 rats. Group control (C) was given 4 mL of distilled water; groups P1, P2, and P3 were given 1ml, 2 ml, and 4 ml cukrik in orally for 14 days. Mixed alcohol contains 4% methanol and 20% ethanol. Examination of histopathological features was carried out by identifying glomerular cells, tubular cells, and interstitial with HE (Hematoxylin and Eosin) stainning using EGTI (Endothelial, Glomerular, Tubular, and Interstitial) scoring. Data were analyze using kruskal wallis and Mann whitney test. With confidence level p<0,01. glomerular and tubular examination there were significant differences with p<0,01, in interstitial examination there was no significant damage found on the instrestitial with p<0,01. Consumption of cukrik produced glomerular and tubular damage on the histopathological image of male Wistar rats' kidneys, but there was no visible damage to the interstitials cell. With higher consumption of mixed liquor will make tubular and glomerular damage heavier.
Extracellular calcium induces neurite outgrowth through calcium-sensing receptors in PC12 HS cells
Authors: Yasushi Hasegawa  , Saori Toda
Published: October 2022

PC12 cells have been used extensively to study neuronal differentiation and neurite outgrowth. However, the effects of extracellular Ca2+ on PC12 cells have not yet been sufficiently evaluated. In this study, we investigated the effect of extracellular calcium using PC12 HS cells, which have high sensitivity to nerve growth factor (NGF). The addition of Ca2+ (1 mM) to the medium induced neurite outgrowth and increased the intracellular calcium concentration. In contrast, the calcium-sensing receptor antagonist NPS2143 suppressed neurite outgrowth and increased the intracellular calcium concentration, suggesting that extracellular calcium promotes neurite outgrowth through calcium-sensing receptors. An increase in extracellular calcium concentration increased phosphorylation of Akt and cyclic AMP response element-binding protein (CREB). Semi-quantitative RT-PCR showed that elevated extracellular calcium increased the mRNA expression of brain-derived neurotrophic factor (BDNF) and platelet-derived growth factor (PDGF), which are regulated by CREB activation. Our results suggest that elevated extracellular calcium can promote the phosphorylation of Akt and CREB through calcium-sensing receptors, resulting in the promotion of neurites. PC12 HS cells are a useful model to investigate the regulation of extracellular calcium via calcium-sensing receptors in neuronal cells.
The impact of slaughter practices on the prevalence of Salmonella in poultry carcasses in slaughterhouses in Bamako (Mali)
Authors: Brahima Sacko  , Satigui Sidibe  , Ousamane Coulibaly  , Kadiatou Coulibaly  , Modibo Kouyate  , Amadou Hamadoun Babana
Published: October 2022

This study, carried out between October 2016 and June 2018, aimed to assess the impact of slaughtering practices on the prevalence of Salmonella in poultry carcasses slaughtered in Bamako markets. It involved 8 slaughterhouses grouped into two categories (A and B). Slaughterhouses classified in category A (75%) were characterized by unsatisfactory hygienic practices. On the other hand, those classified in category B (25%) respected certain principles and standards of slaughter. The prevalence of Salmonella observed in category A slaughterhouse (15.97%) is high compared to that of category B (7.29%). The results of this study have made it possible to establish that the risk factors at the origin of the contamination of poultry products are, among other things, the non-application of basic hygiene rules in the markets and at the level of poultry slaughterhouses, the non-application of good slaughtering practices and the use of rudimentary instruments for slaughtering.
Pengaruh Tingkat Stres Saat Kuliah Daring Terhadap Binge Eating Disorder
Authors: Filipi Hansel , Rasyida Annisa Ullya
Published: October 2022

The outbreak of the Covid-19 virus in Indonesia in 2020 caused many changes in the government sector, work and even education. Online learning has several impacts from various sides, both for educators and on students, one of which is increased stress. Stress has various effects, one of which is eating disorder, therefore the researcher wanted to know whether there is an effect of stress level during online lectures on binge eating disorder. This research is an analytic observational study, with a cross sectional type. This study used a sample of 238 respondents, and the sampling used the quota sampling method. In taking the sample, the researcher used the DASS-42 and BES questionnaires, assisted by the google form instrument. Data processing was carried out statistically using = 0.05 and hypothesis testing using Spearman correlation. Measurement of stress levels showed that 159 respondents had normal stress levels, 38 respondents had mild stress levels, 23 respondents had moderate stress levels, 14 respondents had severe stress levels, and 4 respondents had very severe stress levels. In the measurement of binge eating disorder, there were 212 respondents with no/mild BED levels, 22 respondents with moderate BED levels, and 4 respondents with severe BED levels. The data above was tested for Spearman correlation, and obtained significant results (α = 0.000), where there is an influence between stress levels and binge eating disorder. The level of stress affects the severity of binge eating disorder, therefore it is necessary to do adequate stress management to avoid the possible effects of binge eating disorder, as well as the effects of other stress.
Gambaran Tentang Pengaruh Musim Terhadap Kejadian Pneumonia Anak di Kabupaten Natuna Tahun 2020-2021
Authors: Anwar Rendy Andromeda
Published: October 2022

Penelitian ini dilakukan untuk melihat pengaruh musim terhadap kejadian pneumonia anak di Kabupaten Natuna pada tahun 2020 hingga 2021. Metode yang digunakan adalah deksriptif kualitatif. Sementara, data primer adalah laporan jumlah anak-anak penderita pneumonia pada tahun 2020 hingga 2021. Data sekunder adalah artikel-artikel studi terdahulu dan juga yang bisa mendukung dalam melengkapi penelitian ini. Hasil dari penelitian ini menunjukkan bahwa ada tren fluktuasi pada kejadian pneumonia anak setiap dua bulan. Meskipun begitu, data menunjukkan bahwa tidak selalu tepat setiap dua bulan karena jarak dari kejadian terakhir tahun 2020 adalah pada bulan September kemudian ditemukan kejadian pneumonia anak pada bulan Januari 2021. Sehingga, dapat dilihat bahwa jaraknya tidak selalu setiap dua bulan. Setelahnya tidak ditemukan lagi adanya penderita. Meskipun begitu kejadian terbanyak memang pada bulan-bulan periode musim hujan yaitu pada Januari-Februari di mana masing-masing pada Januari 2020 terdapat satu kejadian pneumonia anak dan pada Februari 2021 ditemukan satu lagi kejadian pneumonia anak. Dua kejadian lain terjadi pada bulan Mei 2020 dan bulan September 2020.
Karakteristik Pasien Dewasa yang Terdiagnosis COVID-19 dengan Komorbid Penyakit Kardiovaskular yang Dirawat di RSPAL dr. Ramelan Surabaya Bulan Juni - Agustus 2021
Authors: Herlambang Lidya Prillyarista
Published: October 2022

COVID-19 is a disease caused by SARS-CoV-2. This disease quickly developed into a worldwide pandemic. In China, comorbidities are found in a quarter of COVID-19 patients. Cardiovascular comorbidity ranks third most compared to other comorbidities. However, in Indonesia there is no data related to the characteristics of COVID-19 patients with comorbidities and what types of cardiovascular disease are found.The design of this research is descriptive research with quantitative research methods.  This research data was obtained by total sampling technique from medical record data. This research was conducted at RSPAL dr.  Ramelan Surabaya in June – August 2021 because on that month, Indonesia experienced the highest spike in COVID-19 cases.

The results showed that COVID-19 patients with cardiovascular comorbidities disease have positive RT-PCR results and are dominated by leukocytosis, neutrophilia, lymphopenia, high level of D-dimer, and pneumonia bilateral. The cardiovascular disease that become the most common comorbidity is hypertension.
PENGARUH PUASA INTERMITEN MENGGUNAKAN METODE PUASA DAUD TERHADAP KADAR SGOT TIKUS PUTIH (Rattus norvegicus) ALIRAN WISTAR YANG DIINDUKSI PARACETAMOL
Authors: Dagradi Eric Mayo , Sukmana Judya , Rahayu Indri Ngesti
Published: October 2022

Background: Intermittent fasting is done with one day of fasting and one day of eating as usual so that it can reduce oxidative stress, inhibit apoptosis and tissue damage which will reduce degenerative diseases. Fasting can activate SIRT1 and SIRT3 to prevent apoptosis by decreasing reactive oxygen species and inhibiting the mitochondrial permeability transition pore component. The accumulation of free radicals is one of the mechanisms that play a role in liver damage so that the SGOT enzyme present in the liver cells will leave and enter the blood circulation, so that the number of these enzymes in the blood increases.

Objective : To prove that there was a decrease in the levels of SGOT (Serum Glutamic Oxaloacetic Transaminase) in male white rats (Ratus norvegicus) of the wistar strain which were fasted intermittently by the Daud fasting method after being induced by Paracetamol.

Method : The research design used is a laboratory experimental research type where the method used is randomized the post only control group design. The experimental animals used were white rats (Rattus norvegicus) wistar strain 2-3 months old with an initial body weight of 150-200gr as many as 32 tails. During the fasting treatment, the research subjects were not given diet and drinking, while the non-fasting subjects were given a standard diet and drank regularly were divided into four groups, namely negative control with a water probe that was filtered for 10 days and 1ml of 1% CMC-Na, positive control with a probe. filtered water for 10 days and induction of paracetamol 400mg/kgBW, treatment 1 with standard diet and induction of paracetamol and treatment 2 with intermittent fasting and induction of paracetamol.

Results: The results of this study indicate that One-Way ANOVA test obtained p value = 0.384. (p > 0.05) then H0 was accepted, there was no significant difference between the SGOT levels of the experimental animal group that was given a standard diet, the experimental animal group that was given intermittent fasting, the experimental animal group that was given a standard diet and paracetamol and the experimental animal group that was given intermittent fasting and paracetamol treatment.

Conclusion:  There is no effect of intermittent fasting with the Dawood fasting method on decreasing SGOT levels in male white rats (Rattus norvegicus) Wistar strain induced by paracetamol.

Keywords: intermittent fasting, SGOT, paracetamol
Kejadian Ablasio Retina Regmatogen Pada Miopia Tinggi: Sebuah Laporan Kasus
Authors: Putriutami Ni Luh Ayu Made Intan Edyassari , Kusumastuti Fitria , Sudiarta I Ketut Edy
Published: October 2022

Latar Belakang: Ablasio retina adalah salah satu kelainan mata yang dapat mengancam penglihatan dan dapat menyebabkan kebutaan. Ablasio retina regmatogen merupakan jenis ablasio yang paling sering ditemukan dan memerlukan penatalaksanaan bedah yang segera dan komprehensif untuk mencegah terjadinya gangguan penglihatan dan kebutaan yang permanen. Insiden kasus ablasio retina regmatogen secara global adalah 1 dibanding 10.000 kasus per tahunnya. Miopia tinggi merupakan salah satu faktor resiko dari ablasio retina regmatogen.

Ilustrasi Kasus: Pasien laki-laki berusia 25 tahun datang ke rumah sakit dengan keluhan mata kanan kabur mendadak dan pandangan seperti tertutup tirai hitam sejak 4 jam sebelum ke rumah sakit setelah mengangkat benda berat dengan riwayat penggunaan kacamata OD S-11.0 D dan OS S-10.0 D. Pada pemeriksaan oftalmologis didapatkan visus OD light perception (+) dengan total detach pada retina, retinal tear pada jam 11-12, macula off, RM (-). Pasien menjalani vitrektomi pars plana dengan tamponade perfluorocarbon dan endolaser. Pasien mengalami peningkatan tajam penglihatan setelah menjalani tindakan tersebut.

Kesimpulan: Seorang laki-laki berusia 25 tahun dengan riwayat miopia tinggi mengalami ablasio retina regmatogen setelah melakukan aktifitas mengangkat benda berat. Tindakan vitrektomi pars plana dengan tamponade perfluorocarbon dan endolaser telah dilakukan pada pasien ini dan memberikan hasil attachment dan hasil tajam penglihatan yang relatif baik.
Skrining Kesehatan dan Pelatihan Senam Ergonomis untuk menurunkan Kadar Asam Urat pada Lansia di Desa Sukorejo Kecamatan Gurah Kabupaten Kediri
Authors: Prihananto Dhian Ika , Wijayanti Endah Tri , Risnasari Norma , Mudzakkir Muhammad , Wati Susi Erna , Aisyah Septi Dewi , Naqiyyah Qothrunnada
Published: October 2022

Penyakit asam urat adalah penyakit yang disebabkan oleh tumpukan asam urat atau kristal pada jaringan, terutama pada jaringan sendi. Upaya untuk mencegah penyakit asam urat bisa dilakukan dengan cara besifat perawatan, pengobatan, pola hidup sehat seperti diet purin dan juga upaya lain. Penatalaksanaan non farmakologis untuk menurunkan kadar asam urat pada penderita penyakit asam urat salah satunya adalah melakukan senam ergonomis yang merupakan kombinasi gerakan otot dan teknik pernafasan. Tujuan pegabdian masyarakat ini adalah melakukan skrining kesehatan pada lansia dan melakukan pelatihan senam ergonomis untuk menurunkan kadar asam urat pada lansia. Langkah-langkah kegiatan yaitu skrining kesehatan dan pratik senam ergonomis. Hasil skrining kesehatan menunjukkan bahwa lansia yang tekanan darah Sistol rendah tidak ada, Lansia yang tekanan darah Sistol normal sebanyak 19 lansia dan lansia yang tekanan darah Sistol tinggi sebanyak 6 lansia. Lansia yang tekanan darah Diastol rendah tidak ada, Lansia yang tekanan darah Diastol normal sebanyak 11 lansia dan lansia yang tekanan darah Diastol tinggi sebanyak 14 lansia. Lansia yang kadar gula darah normal sebanyak 16 lansia, Lansia yang Pre Diabetes sebanyak 2 lansia dan lansia yang Diabetes sebanyak 7 lansia. lansia berjenis kelamin laki-laki yang memiliki kadar asam urat tinggi sebanyak 7 lansia, Lansia berjenis kelamin laki-laki yang memiliki kadar asam urat normal sebanyak 4 lansia. Lansia berjenis kelamin Perempuan yang memiliki kadar asam urat tinggi sebanyak 10 lansia, Lansia berjenis kelamin Perempuan yang memiliki kadar asam urat normal sebanyak 4 lansia. lansia berjenis kelamin laki-laki yang memiliki kadar asam urat tinggi setelah melakukan senam ergonomis selama 1 minggu sebanyak 2 lansia,Lansia berjenis kelamin laki-laki yang memiliki kadar asam urat normal setelah melakukan senam ergonomis selama 1 minggu sebanyak 9 lansia. Lansia berjenis kelamin perempuan yang memiliki kadar asam urat tinggi setelah melakukan senam ergonomis selama 1 minggu sebanyak 5 lansia, lansia berjenis kelamin perempuan yang memiliki kadar asam urat normal setelah melakukan senam ergonomis selama 1 minggu sebanyak 9 lansia. Simpulannya bahwa Senam ergonomis efektif dalam menurunkan kadar asam urat pada lansia baik lansia laki-laki dan lansia perempuan.
Public Speaking for Children of PGRI 1 Vocational School, Balaraja
Authors: Yulianti Neng , Vanchapo Antonius Rino
Published: October 2022

Everyone really capable speak however only some who can concoct words into beautiful language and can interesting public for hear it . So, by simple public speaking means ability speak with do the language " game " in front audience.Public speaking or speak in front general no Becomes something rare in the era Up moment this . All individual sued skilled speak in front of general for convey the goal . In study communication , public speaking skills become part from communication effective that is convey message to audience with the right and interesting way attention . Moment In this case , public speaking is one of the ability absolutely necessary in the global era. Hal the triggered by the demands of the times and existing technology now this is forcing individual for can compete increase quality self . Place importance public speaking skills miss from the definition of public speaking alone . In the ' Empowerment . activity to the Community' (PKM) which involves writer , public speaking training took the place at SMK 1 PGRI BALARAJA, TANGERANG Reason targeting students  student at school the is none other than for equip students knowledge related Skills do public speaking . The majority student class X and XI not yet completely believe self ' when showing herself to public . Therefore with method lectures and exercises  (practice ), students challenged brave to front and present his opinion.
Pemberdayaan Deteksi Dini Risiko Tinggi pada Ibu Hamil di Desa Doyomulyo Kec. Kembangbahu Lamongan
Authors: Darwati Lilik , Fatmawati Vitri , Susila Ida
Published: October 2022

Kegiatan pengabdian kepada masyarakat ini dilakukan untuk meningkatkan pengetahuan dan pemahaman tentang deteksi dini kehamilan resiko tinggi didesa. Waktu pelaksanaan kegiatan. Metode yang diberikan pre test dan post test dengan memberikan pengetahuan tentang deteksi dini kehamilan beresiko tinggi. Penyuluhan menggunakan metode ceramah dan tanya jawab tentang Pengetahuan ibu hamil tentang kehamilan     resiko tinggi diukur dengan memberikan pre test berupa kuesioner yang diisi oleh ibu untuk mengetahui tingkat pengetahuan mengenai deteksi dini kehamilan resiko tinggi yang dilakukan sebelum penyuluhan dimulai . Setelah penyuluhan selesai ibu diberi kuesioner yang sama untuk mengukur peningkatan pengetahuannya. Hasil pemberian pengabdian masyarakat menunjukkan adanya peningkatan pengetahuan tentang kehamilan resiko tinggi pada ibu hamil yang sebelumnya 40 % meningkat hingga 77%. Diperlukan peran serta aktif dari ibu hamil dan masyarakat untuk melakukan deteksi dini kehamilan resiko tinggi.
Strategi Pengembangan Transformasi Sistem Informasi Manajemen Rumah Sakit (SIM-RS) di RSUD dr. Iskak Tulungagung
Authors: Aini Zuhrotul , Nurwijayanti Nurwijayanti , Supriyanto Supriyanto , Susanto Heru Eko
Published: October 2022

Dalam persiapan menuju era disrupsi kesehatan 4.0, masih banyak rumah sakit dan fasilitas pelayanan kesehatan yang menghadapi berbagai tantangan. Tantangan yang paling utama dirasakan dari segi ketidakjelasan peraturan perundangan dan kurangnya harmonisasi regulasi antar kementerian terkait. RSUD dr. Iskak Tulungagung sebagai fasilitas pelayanan kesehatan sekunder merupakan komponen yang tidak terpisahkan dalam proses transformasi kesehatan nasional. SIMRS RSUD dr. Iskak Tulungagung saat ini terfokus utama pada pelayanan billing pasien mulai dari pendaftaran pasien, pelayanan di unit pelayanan, order pemeriksaan ke penunjang medis sampai dengan pasien keluar rumah sakit. Proses digitalisasi dan integrasi seluruh data Rumah Sakit dalam bentuk digital ini memiliki beberapa kendala, sehingga dinilai belum optimal dalam penerapan transformasi SIM-RS RSUD dr.Iskak Tulungagung.Tujuan kegiatan residensi ini adalah untuk menganalisa faktor- faktor yang menjadi penyebab belum optimalnya Pengembangan Transformasi SIM RS di RSUD dr. Iskak Tulungagung dengan analisis fishbone dan USG serta mencari strategi yang tepat dalam upaya pengembangan Transformasi SIM RS di RSUD dr. Iskak Tulungagung dengan analisis SWOT. Hasil penelitian menyatakan masalah yang perlu diprioritaskan penyelesaiannya adalah berkas rekam medis belum terintegrasi secara digital serta setiap operator modul aplikasi hanya bisa mengakses data sesuai dengan unit masing-masing (belum terintegrasi). Strategi yang dapat diterapkan pada kegiatan residensi ini adalah secara bertahap merubah Berkas rekam medis dalam bentuk kertas menjadi digital dan terintegrasi, setiap operator modul aplikasi bisa diakses pada seluruh unit pelayanan serta mulai membentuk sistem Integrasi Layanan Back Office di RSUD dr. Iskak Tulungagung.
Peningkatan Cakupan Booster Vaksin COVID-19 di Wilayah Kerja Puskesmas Sumberpucung
Authors: Mardianto Rudy , Nushah Tutik , Peristiowati Yuly , Ambarika Rahmania , Anggasari Evrin , Nuryanti Ida , Fakhrudin Muhammad Imam
Published: October 2022

Rendahnya cakupan booster vaksin COVID-19 di wilayah kerja puskesmas Sumberpucung karena masyarakat yang kurang memahami pentingnya booster vaksin COVID-19. Berdasarkan identifikasi permasalahan di lapangan menunjukkan bahwa pemahaman masyarakat akan kebutuhan vaksin masih rendah. Tujuan pengabdian masyarakat adalah untuk meningkatkan cakupan booster vaksin COVID-19 di wilayah kerja Puskesmas Sumberpucung. Metode penyuluhan dengan ceramah, tanya jawab dan diskusi secara langsung dengan materi tentang COVID-19 dan vaksin COVID-19.  Media yang digunakan, yaitu laptop, proyektor, microphone, sound system. Penyuluhan dilakukan pada tanggal 16 April 2022 di desa Sumberpucung kabupaten Malang. Sasaran kegiatan adalah masyarakat umum di desa Sumberpucung dengan jumlah peserta sebanyak 56 orang. Hasil penyuluhan menunjukkan capaian vaksin COVID-19, yaitu umur 6-11 tahun dosis 1 sebanyak 110%, dosis 2 sebanyak 99%. Umur 12-59 tahun dosis 1 sebanyak 95%, dosis 2 sebanyak 88%, sedangkan dosis 3 sebanyak 14.92%. Umur >60 tahun capaian vaksin COVID-19, yaitu dosis 1 sebanyak 46%, dosis 2 sebanyak 35%, dosis 3 sebanyak 12.69%. Kesimpulan adalah peningkatan pengetahuan masyarakat melalui penyuluhan tentang COVID-19 dan vaksin COVID-19, memberikan dampak yang cukup berarti bagi tercapainya cakupan booster vaksin COVID-19 di wilayah kerja puskesmas Sumberpucung Malang. Saran, penyuluhan tentang COVID-19 dan vaksin COVID-19 terus dilakukan sebagai upaya peningkatan pengetahuan masyarakat sehingga menggugah kesadaran masyarakat tentang pentingnya vaksin COVID-19. Menghindari informasi yang tidak benar tentang COVID-19 dan vaksin COVID-19 di lingkungan wilayah kerja puskesmas Sumberpucung Malang.
Pemberian Makanan Tinggi Protein di Masa New Normal dalam Pemenuhan Kebutuhan Nutrisi pada Anak Balita
Authors: Vidiasari Vivit
Published: October 2022

Makanan tinggi protein yang diberikan pada anak balita adalah makanan yang diberikan kepada anak usia 6 bulan – 60 bulan baik berupa makanan mikro maupun makro untuk memenuhi kebutuhan hidup dan tumbuh kembang anak. Makanan tinggi protein berupa padat maupu  cair yang diberikan secara bertahap sesuai dengan usia dan kemampuan pencernaan anak (Kemenkes, 2013) makanan tinggi protein  terdiri dari karbohidrat, lemak, vitamin, mineral, maupun protein. Makanan tinggi protein sangat dibutuhkan bagi anak usia 6 – 60 bulan dalam mendukung tumbuh kembang anak. Pertumbuhan anak dapat dilihat dari tinggi badan dan berat badan yang bertambah sesuai dengan usia anak tersebut. Tenaga kesehatan dapat menganalisa pertumbuhan berat badan normal maupun tidak dengan cara penimbangan berat badan pada anak, dan memasukan hasil penimbangan anak tersebut kedalam buku KIA (Kesehatan Ibu dan Anak). Tujuan Pengabdian masyarakat tentang pemberian makanan tinggi protein di masa new normal dalam pemenuhan kebutuhan nutrisi pada anak balita adalah untuk membantu dalam proses pemenuhan gizi sehingga mampu menunjang proses pertumbuhan supaya optimal. Metode Pelaksanaan kegiatan dimulai dengan penimbangan berat badan anak balita usia 6 – 60 bulan. Hasil penimbangan berat badan dianalisa apakah pertumbuhan sesuai dengan usia anak. Kemudian kegiatan inti dilanjut dengan pemberian makanan tinggi protein. Keberhasilan kegiatan ini diharapkan kebutuhan protein anak dapat terpenuhi sehingga anak dapat tumbuh secara optimal sesuai dengan usia anak tersebut.
Upaya Mengurangi Stres pada Ibu Hamil Trimester III dengan melakukan Senam Hamil di Polindes Desa Karangagung Glagah Tahun 2022
Authors: Nikmah Khusnul , Muthoharoh Husnul , Cholidah Maya
Published: October 2022

Kecemasan merupakan suatu kondisi psikologis yang tidak nyaman dengan rasa gelisah yang disertai dengan peningkatan perubahan fisiologis. Peningkatan kimiawi dan kadar hormon yang ditimbulkan oleh rasa cemas tersebut akan bersirkulasi dalam tubuh dan menembus plasenta hingga mencapai janin. Kecemasan merupakan perasaan yang dapat muncul pada setiap orang, baik itu anak-anak, remaja maupun dewasa, begitu juga dengan ibu hamil trimester III yang sedang menunggu kelahiran, tidak menutup kemungkinan mengalami kecemasan. Tujuan dalam pengabdian masyarakat ini adalah mengurangi stress pada trimester III dengan melakukan senam hamil di Polindes Desa Karangagung Glagah. Solusi yang dilakukan adalah dengan memberikan penyuluhan tentang beberapa jenis relaksasi yang diterapkan dalam senam hamil yaitu relaksasi otot dan relaksasi pernapasan dengan sasaran ibu hamil yang ada di Polindes Desa Karangagung Glagah. Evaluasi yang dilakukan adalah memberikan Kuesioner dengan  pertanyaan - pertanyaan tentang senam hamil mulai dari manfaat senam hamil, kapan ibu hamil boleh melakukan senam hamil dan gerakan apasaja yang harus dilakukan oleh ibu hamil. Hasil dari kegiatan pengabdian ini adalah senam hamil efektif dalam mengurangi kecemasan ibu hamil Trimester III di Polindes Desa Karangagung Glagah.
Some properties of Reactive Powder Concrete Contain Recycled Glass Powder
Authors: Al shemaree Zainab , Aljalawi Nada
Published: October 2022

Every year, millions of tons of waste glass are created across the globe. It is disposed of in landfills, which is unsustainable since it does not disintegrate into the environment. This study aims to produce reactive powder concrete by using recycled glass powder and determine the influence on the mechanical properties. This study investigated the effect of partial replacement of cement with recycled glass powder at two percentages (0, 20) % by weight of cement on some mechanical properties (Fresh density, Splitting tensile strength, Impact Strength, and voids%) of reactive powder concrete containing 1 % micro steel (MSRPC). Furthermore, using steam curing for (5 hours) at 90 degrees celsius after hardening the sample directly, RPC was produced using local cement, silica fume, and a super plasticizer, with a w/c (0.2). It was found the Fresh density increased by about (7.27%), splitting tensile strength increased by about (23.5%) at age 28day, energy that causes 1-st crack increased by about (77.7%), energy that causes ultimate failure increased by about (54.9%) at age 60 days, and a reduction in the voids % by about (12.5)% at age 28 day compared with the reference mixture.