bluuebunny/crossref_metadata_2025 huggingface dataset:
INFRARED SPECTROSCOPY
Authors: Tejeswara Rao Voonna Dr.
Published: June 2024

Infrared spectroscopy is a very important tool to identify the functional groups present in the organic molecules. It is a non-destructive method. The IR spectroscopy measures the absorption of electromagnetic radiation in infrared region by a sample placed in the path of light. The frequency at which absorption takes place will depends on the nature of the sample and thus it can be used to identify the nature of the sample. Unlike UV spectrum which consists of very few peaks this technique provides a spectrum containing large number of absorption bands from which more information can be derived about the structure of organic compounds. The IR spectroscopy covers the range 10cm-1 to 13,000cm-1.
MANAGEMENT CHALLENGES IN THE POST COVID-19 ERA
Authors: Rajput Dr. Namita , Jyotsna Dr. , Sharma Dr. Urvashi
Published: June 2024

Due to the COVID-19 pandemic's unforeseen impact on company processes, management has had to put in extra effort to advice and assist workers adjust to the new normal. The epidemic has forced businesses to shift to a new normal, and managers have had to be ready for everything. Our research aims to provide a forum for exploring the challenges encountered by administration in the field of education in the wake of a pandemic. After the pandemic, the research analyses and describes certain specific challenges that the administrative division of every educational institution would face. This story and the study's conclusions are based on an exhaustive examination of key difficulties encountered in the wake of the epidemic.
REAL VS VIRTUAL INFLUENCER: IMPACT ON YOUNGSTER’S PERCEPTION
Authors: Bambeshwar Aditi , Kamble Nachiket , S. Singh Shwetank , A. Soni Nikhil
Published: June 2024

This research paper delves into the realm of virtual influencers and their role in modern marketing strategies. Virtual influencers, also known as CGI influencers, are computer-generated personalities that emulate human traits and personalities. Unlike traditional influencers, they leverage social media platforms like Instagram, Twitter, Facebook, and TikTok to promote products and brands. This paper explores the rise of virtual influencers, their increasing presence on Instagram, and the growing interest from brands to engage with this innovative form of marketing.
ENTREPRENEURSHIP IN THE AGE OF ARTIFICIAL INTELLIGENCE
Authors: Das Ms. Preeti
Published: June 2024

In the chapter "Entrepreneurship in the Age of Artificial Intelligence," the revolutionary influence of AI on business endeavors is explored. It explores how AI technologies influence innovation, business strategies, and decision-making. The abstract emphasizes the synergy between human creativity and AI capabilities for entrepreneurial success, highlighting important insights into navigating obstacles and seizing opportunities in this dynamic landscape.
EVOLVING ETHICAL LANDSCAPE IN BUSINESS
Authors: Aggarwal Dr. Swati , Ambawale Dr. Riddhi , Mandal Mr. Sayan
Published: June 2024

This chapter emphasizes how important business ethics extends beyond legality and covering a wider range of values. It covers contemporary issues involving environmental sustainability—represented by firms like Patagonia—and diversity commitment—exhibited by Salesforce. The conversation also covers new issues in corporate social responsibility, tech ethics, and the need for openness. Notable case studies, such as ones concerning Enron, Rana Plaza, Volkswagen, and Wells Fargo, offer strong instances of the broad repercussions that result from illicit behavior. Following business ethics builds strong stakeholder relationships, enhances risk management processes, and establishes a foundation for long-term, steady development. It also fosters trust. Businesses help establish a responsible and sustainable business environment by conforming to ethical standards.
THE ROLE OF ADVERTISING IN THE DIGITAL ERA: AN OVERVIEW
Authors: Kumar Mr. Rajesh , Smriti Dr. Ani
Published: June 2024

In the contemporary digital era, advertising has undergone a profound metamorphosis, transcending its traditional boundaries to assume a pivotal role in shaping the success and trajectory of modern businesses. This research delves into the multifaceted and dynamic role that advertising plays within the digital landscape. Digital advertising has evolved into a precision instrument, enabling businesses to target specific audiences with personalized content, thereby optimizing the allocation of marketing resources. This paradigm shift has ushered in a new era of audience involvement characterized by real-time interactions, data-driven insights, and unparalleled personalization. The integration of data analytics allows advertisers to measure and refine campaigns with a level of precision previously unattainable. The most common form of advertising in ancient times was word of mouth. Television, radio, magazines, and newspapers have dominated the advertising world in the 20th century, but the Internet has continued to gain popularity among advertisers since its initial rapid growth in the 1990s. Advertising is not limited to media options; ads are placed in physical locations, such as billboards and shop windows. As advertising media change, business practices also change in response, ensuring that the business world, and specifically marketing departments, never stay stagnant. Advertising is a form of communication aimed at promoting a product, service, idea, or brand to a target audience. Advertising messages are carefully crafted to appeal to the target audience’s emotions, desires, and needs. The effectiveness of advertising campaigns is often measured through metrics like reach, engagement, click-through rates, conversions, and return on investment (ROI). Advertising uses powerful media to control people's choices. We also have the power to choose, the power to think for ourselves, and the power to influence others. How we use that power is central to the creation of a good and healthy society. This research explores the various dimensions of advertising in the digital age, emphasizing its transformative influence on brand building, customer engagement, and adaptability to emergent technologies. Ultimately, it underscores how advertising, in its digital incarnation, serves as the linchpin connecting businesses with their target audiences, orchestrating a symphony of strategies and innovations to thrive in an ever-changing digital milieu.
LATENT AUTOIMMUNE DIABETES IN ADULTS (LADA)- AN INSIGHT INTO EARLY DIAGNOSIS AND MANAGEMENT
Authors: Singh Dr. Kamna , Chakotiya Dr. Pranay , Gupta Dr. Richa , Kumar Dr. Vikas
Published: June 2024

Latent Autoimmune Diabetes in Adults (LADA) is a unique form of diabetes characterized by the presence of autoimmune markers, resembling features of both type 1 and type 2 diabetes. LADA patients have functioning beta cells at diagnosis, necessitating therapeutic strategies that aim to improve metabolic control and preserve insulin-secreting capacity. The presence of glutamic acid decarboxylase 65 autoantibodies (GADA) is a hallmark of LADA, along with other less frequent autoantibodies. Genetic susceptibility overlaps with type 1 diabetes, including specific HLA genes and polymorphisms within insulin and protein-tyrosine-phosphatase nonreceptor 22 (PTPN22) genes. Management of LADA involves early recognition, lifestyle modifications, and judicious use of hypoglycemic agents such as insulin sensitizers and dipeptidyl peptidase 4 inhibitors (DPP-4i). Individualized care and regular monitoring are essential to optimize glycemic control and preserve beta-cell function in LADA patients.
ARTIFICIAL INTELLIGENCE IN DIAGNOSTIC PATHOLOGY: ADVANCEMENTS AND APPLICATIONS
Authors: BK Dr. Praveen
Published: June 2024

The chapter explores the rapid evolution of artificial intelligence within the field of diagnostic pathology, showcasing its potential to revolutionize patient care and advance precision medicine. The narrative delves into the applications and advancements of AI, particularly deep learning algorithms, in histomorphological analysis and disease diagnosis across various medical specialties. The integration of AI into pathology workflows, while presenting promising opportunities, also confronts challenges related to data privacy, interpretability, and seamless clinical integration. The discussion navigates through the concerns of pathologists being replaced by AI algorithms, emphasizing a nuanced perspective that positions AI as a complement to, rather than a replacement for, human expertise. By relieving pathologists of routine tasks, AI integration enhances efficiency, allowing focus on complex patient care aspects. The chapter also addresses the practical, financial, and regulatory hurdles faced by healthcare institutions in adopting AI solutions in pathology. Real-world applications and challenges in developing AI models for pathology are highlighted, offering insights into how these technologies impact disease diagnosis, prognosis, and therapy response assessment. The integration of AI algorithms into routine pathology practice not only promises enhanced diagnostic accuracy but also the discovery of novel disease markers, contributing to personalized patient care.The future prospects of AI in surgical pathology are discussed, envisioning enhanced diagnostic accuracy, personalized medicine, rapid teleconsultations, and integration with multi-omics data. The chapter concludes by emphasizing the collaborative partnership between pathologists and AI algorithms as essential for unlocking the full potential of this groundbreaking technology in surgical pathology. The transformative opportunity presented by AI in elevating patient care to new heights is highlighted, paving the way for a brighter and more innovative future in diagnostic pathology.
EMERGING AND RE-EMERGING INFECTIOUS DISEASES: A PERSISTENT GLOBAL HEALTH CHALLENGE
Authors: Kumar Dr. Vikas , Saraswat Dr. Satender , Goyal Dr. Ankur , Shekh Dr. Nadim , Gupta Dr. Richa
Published: June 2024

Emerging and re-emerging infectious diseases persist as a pressing global health challenges, transcending borders and eras. Despite medical advancements, these diseases continue to threaten public health, economies, and societies. This chapter surveys the landscape of emerging infections, exploring their origins, drivers, and the urgent need for a coordinated worldwide response. The 21st century has seen the rapid emergence of novel pathogens and resurgences of familiar diseases. Zoonotic transmission highlights the interconnectedness of human, animal, and ecological health. Globalization accelerates disease spread, necessitating international co-operation. Urbanization, climate change, and antimicrobial resistance compound these challenges. Noteworthy recent infections like SARS, Ebola, Zika, and COVID-19 underscore the importance of a proactive approach to disease surveillance, readiness, and containment. The abstract emphasizes the enduring relevance of the 1997 World Health Organization slogan, "Emerging Infectious Diseases: Global Alert, Global Response." In conclusion, these diseases demand constant vigilance, interdisciplinary collaboration, and innovation. A fortified defense against infectious diseases is essential for safeguarding global health and well-being.
UNDERSTANDING AYURVEDA – AGE OLD SCIENCE FOR MODERN TIMES
Authors: Agarwal Dr. Nipun , Gupta Dipali , Khare Pragati
Published: June 2024

Many academics concur that the oldest form of medicine is Ayurveda. The Sanskrit name for Ayurveda is "The Science of Life." Ayurvedic knowledge, also known as the "Mother of All Healing," has its origins in India and has been practised for more than 5,000 years. It derives from the ancient Vedic culture and has been transmitted orally for a very long time from great teachers to their disciples. While the majority of this knowledge is unavailable, a little fraction has been kept in writing. Ayurveda is the source of many of the natural therapeutic concepts currently practised in the West, including homoeopathy and polarity therapy. (Vasant, 1984).
CONCEPTUALIZATION OF KHARALIYA RASAYAN AS CORNERSTONE AMONG AYURVEDIC MEDICINES
Authors: Kar Dr. Ranjita , Mishra Dr. Abhaya Kumar , Panda Dr. Pradip Kumar
Published: June 2024

There are four varieties of Parad Murchit Rasaousadhies: Kharaliya Rasayan, Parpati Rasayan, Kupi Pakwa Rasayan, and Pottali Rasayan. Among them is Kharaliya Rasayan .It is a Rasaousadhi form (Mercurial preparation) that is said to be the initial form of Rasayan. These formulations are entirely produced in Khalwa Yantra through a rigorous trituration process, and the finished product is known as "Kharaliya" or "Khalviya Rasayana." There are several mercurial formulations, however the bulk of them include Kajjali (Black Mercury Sulphide). Kajjali, the base of the majority of formulations, contains Sodhita Parad (Mercury) and Sodhita Gandhak (Sulphur). It may also include dried herbs in powder form, as well as different metals and minerals that have been purified or burnt. So, by including a variety of components and mixing them with appropriate amounts of fresh juices from various plants, and repeating the Bhavna process, an effective and original product is generated. As a result, the major element of Kharaliya Rasayan is highlighted in this chapter.
FUTURISTIC TRENDS IN MEDICAL SCIENCES: A BRIEF OVERVIEW
Authors: Bedi Prof. Dr. Neeraj
Published: June 2024

Welcome to "Futuristic Trends in Medical Sciences." This book chapter explores the exciting advancements, ground breaking technologies, and innovative approaches that are shaping the future of healthcare. As we stand at the forefront of a new era in medicine, where science fiction is becoming a reality, it is crucial to understand and embrace the transformative potential of these emerging trends. From artificial intelligence and robotics to regenerative medicine and telemedicine, this book aims to provide a comprehensive overview of the futuristic landscape in medical sciences. Join us on this captivating journey as we explore the possibilities that lie ahead and envision a future where healthcare is revolutionized to benefit all humankind.
A TOE WALKING WITH CLINICAL INTERPRETATION AND MANAGEMENT – AN OVERVIEW
Authors: Chandramohan. R Dr. , R. Sedhunivas Dr. , Senthilkumar. S Dr.
Published: June 2024

While frequent in young children, toe walking can develop into a persistent Problem with uncertain long-term effects. This thorough analysis dives into the complexity of toe walking in children, emphasizing the mysterious nature of "idiopathic toe walking" (ITW) or "habitual toe walking" (HTW) with no known explanation. While neurological conditions like cerebral palsy or muscular dystrophy can cause toe walking, ITW poses a distinct problem because it typically manifests in otherwise healthy youngsters. This chapter looks at the traits, categories, and methods of diagnosis for ITW, emphasizing the value of gait analysis and setting it apart from other developmental and neuromuscular disorders. It investigates several reasons, such as genetics and deformities of the muscles. ITW's administration is still debatable. The review compares surgical techniques like Achilles tendon lengthening with non-operative therapies including physical therapy, bracing, and casts, critically analyzing their efficacy. It highlights that age-appropriate treatment plans and early intervention are critical for the best results. It acknowledges the ongoing discussion regarding the necessity of interventions and goes over several treatment approaches, such as gait re-education and shoe adjustments. To sum up, this review provides a thorough and informative investigation of toe walking in children, especially the mysterious ITW. It gives parents and medical professionals important information to help them negotiate the challenges of diagnosis and treatment, ultimately leading to the best possible results for kids With this illness.
LAPAROSCOPIC SURGERY IN CHILDREN: THE ANAESTHETIC PERSPECTIVE
Authors: Singhal Meghna , Hirani Kshitiz , Singhal Isha , Khurana Bisman Jeet Kaur
Published: June 2024

Laparoscopic surgery has revolutionized the field of abdominal, pelvic, urological and gynaecological procedures, offering numerous benefits over traditional open surgery. Laparoscopic surgeries are gaining popularity in children. However, when it comes to their management, special considerations and adaptations are necessary to ensure safe and effective outcomes. This chapter aims to provide a comprehensive overview of the unique challenges and considerations in laparoscopic surgery for paediatric patients. The chapter begins by highlighting the physiological changes that occur during laparoscopy in paediatric patients. These include the effects of increased intraabdominal pressure and its impact on cardiovascular, respiratory and other systemic function. Understanding these changes is crucial for anaesthesiologists and surgeons to optimize patient care. Anaesthesia management is a critical aspect of laparoscopic surgery in paediatric patients is highlighted. Gas absorption, particularly carbon dioxide, can have adverse effects on respiratory and acid-base status. The chapter discusses strategies for minimizing gas absorption and maintaining appropriate ventilation and oxygenation. Patient positioning plays a vital role in laparoscopic procedures and specific considerations must be made for paediatric patients. Proper positioning ensures optimal access to the surgical site while minimizing the risk of neurovascular compromise or injury. Additionally, the chapter addresses postoperative care and highlights the importance of monitoring and managing potential complications. This includes maintaining normothermia, implementing multimodal analgesia techniques and promoting early mobilization and recovery. By understanding the unique challenges and considerations associated with laparoscopic surgery in paediatric patients, healthcare providers can improve patient outcomes and provide safer and more effective care.
BIOPRINTING: ADVANCEMENTS, APPLICATIONS AND CHALLENGES IN REGENERATIVE MEDICINE
Authors: Sharma Dr. Priyanka
Published: June 2024

This chapter introduces the field of bioprinting within regenerative medicine, focusing on the precise fabrication of 3D structures using living cells, biomaterials, and bioactive molecules. Exploring potential applications, it highlights the role of bioprinting in addressing organ shortages, enabling personalized transplantation, and advancing regenerative therapies. The bioprinting process, including pre- bioprinting design, main printing techniques, and post-printing stabilization, is detailed. Case studies illustrate clinical applications, from wound healing to cardiac tissue repair. Challenges include material selection, industrial scaling, complex structure replication, vascularization, and ethical considerations. The chapter underscores the transformative potential of bioprinting in medicine, emphasizing ongoing research to optimize techniques and establish specific regulations for its safe and ethical use.
EFFECT OF INTERFERENTIAL THERAPY ON PAIN LEVEL IN PEOPLE WITH TRAPEZIUS MYALGIA FOLLOWING A SINGLE TREATMENT SESSION
Authors: Dutta Pinky
Published: June 2024

Trapezius myalgia is a leading disability. The microcirculation is disrupted by the mitochondrial disruption, which also results in discomfort and stiffness. By activating large-diameter nerve fibres, IFT(interferential therapy) causes analgesia. IFT is typically offered in a single session per day. IFT is known to alleviate pain; however, it is unknown if the hypoalgesic effect lasts up to 24 hours before the delivery of the following session. Therefore, it becomes necessary to assess IFT's impact on trapezius myalgia sufferers 24 hours after the session. To evaluate and compare the degrees of pain in trapezitis prior to the treatment, just after, and 24 hours after providing an IFT session Subjects were divided into experimental and control groups. Study group received IFT with suction electrode and a sham therapy to control group. Visual Analogue scale(VAS) and Pain pressure threshold(PPT) was measured before the treatment, immediately after, and 24 hours. Also, a patient report card was given. The experimental group showed a significant decrease in pain level and an increase in pressure threshold after the therapy. IFT and sham therapy both reduced pain right away and for up to 24 hours within and between the groups. But when compared to sham therapy, the pain was significantly reduced by IFT after 24 hours rather than right away. This study suggests that although the immediate effect of IFT on pain levels is not obvious, it has definitely been demonstrated to generate a substantial effect post 24 hours, therefore demonstrating that the IFT has hypolagesic effect which lasts for 24 hours after a single session. IFT has a hypoalgesic effect on persons with trapezius myalgia's pain level that lasts for 24 hours after a single session.
ROLE OF MINI IMPLANTS IN ORTHODONTICS
Authors: Paul Dr. Rahul , Yadav Dr. Deepti , Sharma Dr. Ish Kumar , Sairal Dr. Anudeep
Published: June 2024

The Chapter discusses the significant role of temporary anchoring devices (TADs) or mini-implants in orthodontics, emphasizing their evolution and applications in various treatment modalities. Historically, orthodontic anchorage has been a challenge, and TADs have emerged as a practical solution. In the late 20th century, various skeletal anchorage devices, such as prosthetic implants, palatal implants, micro-implants, mini-plate screws, and onplants, were introduced. TADs, also known as orthodontic implants, gained popularity due to their small size, ease of insertion and removal, immediate loading capability, and ability to provide absolute anchorage with minimal patient compliance. The anchorage protocols are critical in orthodontics to direct forces properly and prevent unintended tooth movements. Extraoral anchorage, although effective, is less preferable due to patient discomfort and compliance issues. The term 'absolute anchorage' refers to the stability of the anchorage unit, and TADs have made achieving absolute anchorage feasible. The Chapter details the advantages of mini-implants, including their versatility in placement, simplicity of surgical procedure, rapid healing, easy removal, and lower cost compared to conventional dental implants. Anatomic considerations, such as cortical bone density and thickness, play a crucial role in implant placement. Clinical applications of TADs in orthodontics are discussed, including intrusion of anterior teeth, correction of gummy smiles, retraction of anterior teeth, correction of a canted occlusal plane, correction of dental midline discrepancies, molar mesialization, molar distalization, upper third molar alignment, extrusion of impacted canines, and correction of molar crossbites. The Chapter highlights the benefits of TADs in achieving precise tooth movements with minimal patient discomfort and reduced treatment time. The complications associated with TADs, such as inflammation of soft tissues, occasional screw fracture, and potential displacement during orthodontic loading, are acknowledged. Studies on the behavior of miniscrews under orthodontic loading are cited, indicating some forward tipping but overall stability. The application of TADs in specific cases, such as molar intrusion, upper third molar alignment, and correction of impacted canines, is illustrated. The Chapter concludes by introducing MARPE (miniscrew assisted rapid palatal expansion) as a nonsurgical alternative for maxillary expansion in individuals with limited growth potential.
WELL DIFFERENTIATED THYROID CANCERS
Authors: Khan Dr Amena
Published: June 2024

Well differentiated thyroid cancers are a class of cancers that have one of the best prognosis. They include papillary and follicular cancers with a few of their subtypes. They often present as solitary thyroid nodules. Cervical lymph node metastases is more common in papillary carcinoma than follicular carcinomas. Diagnosis is made with the help of thyroid ultrasonography coupled with fine needle aspiration cytology. Surgical management can either be lobectomy for low risk, small tumors or sub total/ total thyroidectomy for larger, high risk tumors. Total thyroidectomy enables better post operative follow up via serum thyroglobulin levels and radio iodine scans. Remnant thyroid tissue is ablated with radioiodine and patients are kept on suppressive doses of thyroxine to decrease risk of recurrence. 10 year prognosis is usually >95%, especially in patients with PTC.
NANOTECHNOLOGY, NANODEVICES AND LABORATORY DIAGNOSIS
Authors: Shrivastava Jyoti Priyadarshini
Published: June 2024

Nanotechnology is a revolution of 20th century .It has a great role in diagnostics, biomedical research and clinical practice in the medical field .Nanotechnology is study of extremely small structures. Richard Feyman is considered as father of nanotechnology. Nano particles posess special properties of electrical conductance, reactivity, absorption, optical and physical strength etc. which make them highly useful to apply in human diagnostis. Various types of Nano devices are in use like diamond and salt nanoparticles, carbon nanotubes ,Nano rods ,Nano wires etc. Nano particles have wide applications in fields of immunology, immunohistochemistry, genotyping, cancer and infection detection and most importantly vaccine development. Nanotechnology will enable personalized, customised medicine as point of care diagnostic and integration of diagnostics and therapeutics. Nanotechnology will lead to paradigm shift in the field of diagnostics in healthcare.
MALIGNANT PERSISTENT PULMONARY HYPERTENSION IN NEONATES
Authors: Amalraj Julie Christy , G Sumathy
Published: June 2024

Persistent Pulmonary Hypertension is a crucial condition requiring emergency intervention. Birth is a phase of transition from fetal to neonatal life. Fetal respiration occurs through the placenta. Gaseous Transition occurs from maternal to fetal through the passive ionic movement in the placenta. After birth gaseous transfer occurs through the lung with decreased pulmonary vascular resistance and increased pulmonary blood flow. Vasoconstriction can cause hypoxia in neonates. Hypoxia can be due to vascular resistance that progressively decreases during the first few weeks of life. The other abnormalities include abnormal pulmonary hypoplasia, meconium aspiration syndrome (MAS), respiratory distress syndrome (RDS), Congenital Diaphragmatic Hernia, etc. Circulatory transition during birth can lead to persistent pulmonary hypertension. This chapter explains persistent pulmonary hypertension with two case presentations.
LITERATURE REVIEW OF PRE-OPERATIVE ANXIETY
Authors: R Sonani Dr. Snehal , Dudhamal Dr. T. S.
Published: June 2024

Preoperative anxiety is a prevalent and a multifaceted psychological phenomenon that affects individuals facing surgery. This literature review provides an extensive analysis of the existing research on preoperative anxiety, synthesizing findings from various studies and shedding light on its prevalence, causes, consequences, assessment, and management strategies. The review explores the physiological, psychological, and sociodemographic factors contributing to preoperative anxiety, as well as its impact on surgical outcomes, patient satisfaction, and healthcare costs. Additionally, it delves into the various assessment tools used to measure preoperative anxiety, discussing their strengths and limitations. The chapter also highlights a range of interventions aimed at alleviating preoperative anxiety, including pharmacological, psychological, and complementary approaches. Understanding preoperative anxiety is crucial for healthcare professionals, as it can inform strategies to enhance patient care and surgical outcomes, ultimately improving the overall quality of healthcare delivery.
EXPLORING THE FRONTIERS OF REGENERATIVE ENDODONTICS
Authors: Pandey Dr. Jayati , Gupta Dr. Aditya , Singh Dr. Isha , Sinha Dr. Dakshita Joy
Published: June 2024

Root canal treatment is one of the most common dental procedures, however it does not restore the vitality of the tooth. As the technology and scientific research in the dental field is booming, newer dental procedures to replace conventional root canal treatment are emerging, one of them being regeneration of the pulpal tissue. Techniques like pulp autotransplantation and cell homing technique have also been attempted to regenerate lost vital pulpal tissue. This chapter briefly discusses scaffolds, stem cells, clinical considerations for regenerative endodontic treatment and its histological aspects.
THE GENETIC UNDERPINNINGS: DECIPHERING THE INHERITANCE PATTERN OF THALASSEMIA
Authors: Upadhyay Kirti , Nigam Nitu , Gupta Surbhi , Rawat Neha , Verma S P , Kushwaha Rashmi
Published: June 2024

Thalassemia, a congenital blood illness brought on by incorrect haemoglobin synthesis, causes anaemia and other health issues. Understanding its genetics is crucial for understanding how it is passed on and how it affects the affected individuals and their families. The impact of the condition on RBC, the pathogenesis of thalassemia, clinical presentation and diagnostics, thalassemia therapy, and future prospects of thalassemia developments and promising paths are the main topics of this chapter. Additionally, it looks at the genetic foundation, pattern of inheritance, and structure and function of haemoglobin in RBC. We also offer historical context and comments on the identification and discovery of thalassemia from eminent experts in the area.
USE OF CAD/CAM IN DENTISTRY
Authors: A Jamnare Dr. Shubhangi , Wasu Dr. Prashant , B. Sable Dr Jyoti , Ambadkar Dr Shraddha , Chorey Dr Swati
Published: June 2024

A series of closely linked steps are required to make a fixed dental prosthesis. After any preparation, dentist must take an impression of prepared tooth, together with adjacent d opposing teeth, using elastic impres­sion material. This impression is used obtain a hard stone model, and a wax pattern of the crown or inlay is carved. The actual cast restoration is obtained using the "lost wax method.1
DOES THOUGHTS AFFECT THE DNA OF THE FOOD?
Authors: Rawat Neha , Nigam Dr. Nitu , Gupta Surbhi , Kumar Praveen , Upadhyay Kirti
Published: June 2024

The increased interest in the scientific study of unseen forces and the possible outcome of these forces on subjects important or used daily by human body in the form of nourishment or nutrients are being studied. According to researches, the practices of different cultures and beliefs that were studied have been capable of creating changes in the living matter and convey out the changes accordingly. Experiments over the few years have inspected whether intention of a human thoughts affects the properties of nourishment we select. The grownup human body includes about 70% water any alterations via human recognition could additionally have an effect on the human frame capabilities. Researchers have shown human consciousness to be an issue for growth of plants and cultured cells. Foods have been studied as a part of creating and altering the properties in the human body by its components and providing beneficial nutrients required for the body. Nutrition, genes and environmental factors have proven to alter the body functioning and cause irregularities which have been studied for many years. The human body consumes most of the plant derived meals which may trade the properties of the food as human consciousness has established to have an effect on the DNA or properties of plant The potential of human consciousness to trade the structure of water and modify the adjustments in the growth of cultured human brain cells is in interest to complementary and alternative medicine research, and mainly for cures regarding purpose. There are nevertheless many studies to proclaim the consequences of human intention on foods.
SOME ACTIVE COMPOUNDS PREVENTING AND TREATING BREAST CANCERS
Authors: Srivastava Dr. Shikha , Siddiqi Dr. Zeba
Published: June 2024

In the whole world, cancer is the second main cause of death. Currently, many advanced medicines and techniques are available for the treatment and control of cancer, but all of them have many undesirable side effects. Although medicinal plants and their derived products, which are used as natural therapies, are safe to use in the prevention and treatment of cancer, Recently, many plant products have been used for the prevention and treatment of cancer, but in this chapter, we discuss some important medicinal plants that have shown promising anticancer effects, such as ginseng, garlic, turmeric, green tea, linseed, and black cumin. Further clinical studies are required to determine the effect of these medicinal plants in the treatment and prevention of cancer in humans.
UNVEILING THE NEXUS OF NON-MODIFIABLE RISK FACTORS IN ACUTE CORONARY SYNDROME: IMPLICATIONS FOR PERSONALIZED CARE AND PREVENTION
Authors: Raza Syed Tasleem , Rizvi Saliha , Fatima Kaynat , Eba Ale , Srivastava Sanchita
Published: June 2024

Acute Coronary Syndrome (ACS) encompasses a spectrum of critical cardiovascular conditions, including unstable angina and myocardial infarction (MI), and represents a significant global health challenge. This review provides a comprehensive analysis of non-modifiable risk factors associated with ACS, shedding light on the importance of thorough risk assessment and tailored interventions for individuals with these risk factors. The review begins by emphasizing the profound impact of ACS on public health, especially in low and middle-income countries, with a focus on the escalating prevalence in India. Furthermore, the review delves into the mechanisms contributing to ACS, which include plaque rupture associated with inflammation, plaque rupture without significant macrophage accumulations, plaque erosion causing non-ST-segment-elevation MI, and vasospasm affecting both epicardial arteries and coronary microcirculation. The primary focus of this review is on non-modifiable risk factors, with a detailed exploration of age, gender, family history, and ethnicity as significant contributors to ACS risk. It also draws on recent studies to provide insights into the complex interplay of these non-modifiable risk factors and their implications for ACS management. It underscores the necessity for tailored, culturally sensitive healthcare approaches to improve ACS outcomes across diverse populations.
MICRORNA AS MARKERS INVOLVED IN THE PROGRESSION OF CERVICAL CANCER
Authors: D. Pratap Pushpendra , Raza Syed Tasleem , Ahmad Sharique
Published: June 2024

The most communal cancer-related cause of fatality in women in emerging nations is cervical cancer (CC). Persistent infection with hr-HPV primarily 16/18 is acknowledged as major risk factor for cervical carcinogenesis. However, the fact that only a small number of women who have morphologic manifestations of HPV infection develop invasive illness suggests the presence of additional variables in the development of CC. Conserved tiny ncRNAs termed as miRNAs, control the genes expression, comprising those intricate in basic living processes and human cancer. MiRNA Dysregulation has frequently been linked to CC. Evaluating the miRNAs impacted by the infection process of HPV and the miRNAs that support the growth and upkeep of malignant cervical tumour cells are the main objectives of this study.
REVOLUTIONIZING FORENSIC MEDICINE THROUGH VIRTUAL AUTOPSY
Authors: Gupta Dr. Richa , Kumar Dr. Vikas , Mittal Dr. Anjesh , Chegudi Dr. Manogna
Published: June 2024

Virtual autopsy, also known as digital autopsy or post-mortem imaging, is an innovative approach of conducting post-mortem examinations without conventional surgical dissection. This technology has emerged as a promising alternative to conventional autopsies in recent years, with the potential to provide more comprehensive and less invasive examinations of deceased individuals. The utility, effectiveness, and restrictions of virtual autopsy in forensic medicine are all covered in this paper, along with a discussion of the various imaging modalities used in virtual autopsy, such as computed tomography (CT) and magnetic resonance imaging (MRI), and their individual benefits and drawbacks. This paper also emphasized on the potential benefits of virtual autopsy, including faster turnaround times, decreased costs, and improved safety for pathologists and technicians and also the challenges and limitations of virtual autopsy, including the need for specialized training and expertise, limited access to technology in certain areas, and the inability to detect certain types of injuries and lesions is also explored. Virtual autopsy has generally become a useful tool in the field of forensic medicine, providing a quick and effective replacement for traditional autopsies. Virtual autopsy is probably going to be more and more common in the years to come as technology develops and gets better.
ASSESSMENT OF KNOWLEDGE AND PRACTICES OF MEDICAL STAFF REGARDING OCCUPATIONAL POST EXPOSURE PROPHYLAXIS AGAINST HIV, HBV AND HCV INFECTIONS IN A TERTIARY CARE HOSPITAL, LUCKNOW
Authors: Verma Neera , Himanshu D. , Paliwal Saurabh , Gupta Neetu , Shukla Suman , Verma Kallol
Published: June 2024

To assess the level of knowledge regarding post exposure prophylaxis (PEP) among residents, staff nurse and other employees working in a Tertiary care Hospital. Questionnaires were distributed among residents, staff nurse and other employees working in a Tertiary care Hospital. Out of 600 questionnaires distributed, 496 participants took part in the study. Ninety nine (20%) were residents, 214(43.1%) were staff nurse and 183 (36.9 %) were other staff members. Most of the HCWs were able to answer when they were enquired about the PEP. Regarding knowledge of HCWs on potentially infectious material that causes HIV, HBV and HCV infections, their responses were quiet poor. Of 496 respondents, 17 residents, 28 staff nurse and 14 other staff had needle prick and their responses regarding practices of PEP were not satisfactory. In this study 338 respondents (88 residents, 148 staff nurse and 102 other staff members) had complete Hepatitis B vaccination. This study recommends mandatory training of HCWs on PEP, Universal Work Precautions and vaccination strategies in various departments.
LEVERAGING ARTIFICIAL INTELLIGENCE IN THE COMPARATIVE ANALYSIS OF MEDICINAL APPROACHES FOR MENSTRUAL DISORDERS A COMPREHENSIVE STUDY OF PCOD AND PCOS THERAPIES
Authors: V Chalapathy Chethana , Maheshwari Disha , Nalinan Archana , Khandelwal Lahar , Awasthi Shruti
Published: June 2024

The delicate balance of menstrual cycles and fertility is orchestrated by the female reproductive system, which functions as an intricate symphony of hormones and physiological processes. However, the two common and complicated menstrual disorders polycystic ovary disease (PCOD) and polycystic ovarian syndrome frequently interfere with this natural rhythm (PCOS). Many women around the world are affected by these conditions, which have an impact on both their reproductive health and general well-being.
BIOMEDICAL SCIENCE
Authors: Sah Dr. Ashok Kumar , Rao Mr. Darla Srinivasan , Kumar Mr. Vivek , Sharma Ms. Prigya , Vashishtha Mr. Ankur
Published: June 2024

Biomedical science is a multifaceted and ever-evolving field at the intersection of biology, medicine, and technology. This chapter delves into the fundamental concepts that underpin the practice and progress of biomedical science. It provides an overview of the historical development of this discipline, tracing its roots from ancient medical practices to the cutting-edge research of today. The chapter explores the key components of biomedical science, including cellular biology, genetics, physiology, and pharmacology. It highlights the critical role of these foundational sciences in understanding the mechanisms of health and disease. Moreover, it discusses how advances in technology have revolutionized data acquisition, analysis, and interpretation, ushering in the era of precision medicine and personalized healthcare. Furthermore, the chapter emphasizes the interdisciplinary nature of biomedical science, showcasing how collaboration between scientists, clinicians, engineers, and other professionals is essential for translating laboratory discoveries into clinical applications. It also touches on the ethical considerations and regulatory frameworks that guide biomedical research and practice, ensuring the responsible and equitable use of scientific knowledge.
FROM PIONEERS TO FUTURE GENERATIONS, A WAY OF LIVING – AYURVEDA
Authors: Azeem Mohd. Umar , Saini Yashika , Singh Sonalika
Published: June 2024

Ayurveda, often referred to as the "Science of Life," is a traditional holistic medical practice that has its roots in the Indian subcontinent and dates back thousands of years. This chapter examines the development of Ayurveda from its early pioneers to its current relevance and prospective applications in influencing future generations' lifestyles through the adoption of an integrated approach and the fusion of Ayurveda with contemporary sciences. This chapter explores the growing data that supports Ayurvedic practices by drawing comparisons to contemporary science. The concepts underlying Ayurvedic ideas, such as how some herbs affect biological processes and how practising mindfulness reduces stress, are starting to be understood by science.Ayurveda is recognised as a profound "Way of Living" that has endured over the ages. Pioneers and practitioners have kept its ancient wisdom alive, and it continues to offer wisdom and direction for overcoming the challenges of modern life. Ayurveda has the power to create a future that is healthier and more peaceful by encouraging a closer connection between people, their environment, and their inner selves.
MANAGING RHEUMATOID ARTHRITIS: INSIGHTS INTO POSTPARTUM ONSET AND HOLISTIC APPROACHES
Authors: Kaur Dr. Harpreet , Lakshmikanth Dr. Sankara , Yadav Dr. Sonal
Published: June 2024

Rheumatoid arthritis (RA) is a common autoimmune condition influenced by a combination of intricate genetic and environmental factors that play a role in its development. Our review examines the multifaceted aspects of RA, focusing on its development following childbirth in women, potential triggers, and strategies for management during breastfeeding and beyond. Diagnosis involves clinical evaluation, serological tests, and imaging studies, emphasizing early and accurate identification for prompt intervention. RA management encompasses disease-modifying drugs, surgery, and physical therapy, while emerging dietary and lifestyle interventions, including fasting, veganism, probiotics, and exercise, hold promise. Mindfulness, yoga, and exercise training are complementary approaches gaining traction in improving RA symptoms and overall well-being. Balancing symptom control with pregnancy and breastfeeding safety is crucial in managing RA during and after pregnancy. In summary, this review underscores the intricate nature of RA, its potential postpartum occurrence, and a multifaceted management approach, highlighting the need for a holistic strategy tailored to the unique challenges faced by women with RA during this life phase.
BALLOON BLOWING EXERCISES: EFFECTIVE FOR RESPIRATORY PARAMETERS A SYSTEMATIC REVIEW & META ANALYSIS
Authors: Thapa Rajni , Supriya Ms.
Published: June 2024

In India, the children younger than 15 years old involve around 35 percent of total population. This special group of the society ought to be secured as prime concern in all nations. A Meta Analysis manifested that 1.9 million children expired from acute respiratory infections in 2009 worldwide and a normal death rate is 4.3 million consistently are alluded to intense respiratory infections.
UNCOVERING THE HIDDEN MAGIC AND GOTHIC THROUGH UNCANNY AND UNHOMELY IN ANTHONY HOROWITZ’S RAVEN’S GATE
Authors: Malik Rishabh
Published: June 2024

This paper packs its bags for a journey to a place which is not down on maps but in children’s fictional worlds. This journey will be through weary roads abutted by gothic on one side and magic on the other. The road this paper takes leads to the destination of Sigmund Freud’s uncanny from where the study will chart the route to Homi Bhabha’s Unhomely. The journey will overcome its obstacles of dark and formidable magical worlds, on looking back to which, the research will trace the uncanny and the unhomely. This paper studies the genre of gothic and magic in Anthony Horowitz’sRaven’s Gate (2007) through the penetrating lens of “The Uncanny” (1919) by Sigmund Freud, translated by David McLintock, and the concept of unhomely from Homi K. Bhabha’s 1992 essay “The World and the Home”. By charting this journey, this paper explores how the selected novel has incorporated and defied the traditional gothic tropes. With this exploration, the paper establishes the correlation between the real world and the magical world which establishes a connection with the uncanny and unhomely by extensively studying the selected novel and its protagonists’ experiences.
CRITICAL INTERPRETATION: AN EXPLORATION OF THIS EDUCATIONAL PRACTICE THROUGH SARAH FIELDING’S THE GOVERNESS (1749)
Authors: Malik Dr. Raman
Published: June 2024

This paper highlights two important aspects regarding girl’s education in England from the early to the mideighteenth century when interpreted through Sarah Fielding’s The Governess (1749). Former exploration of differences in education on the basis of gender and class in institutions founded by the Church or established by the English government provide extensive information on the type of education given to girls. This chapter, however, explores the type of education deemed necessary for girls and establishes, one, proper instruction for directing their imagination and two, critical interpretation of every knowledge they receive to be the distinguishing features of a good education. Such an education not only helps them in becoming exemplary students whose investigative minds aim at interpreting reasons behind every line written in books but also dutiful citizens who aim for personal happiness and social development. Sarah Fielding through her ideal educator tries to persuade the eighteenth century educational institutions to redirect their objectives toward the betterment of young readers. According to her, teachers in such institutions should aim at the intellectual development of their students through proper instructional teaching rather than preaching religion that remains irrelevant as a subject for children to study. Fielding’s only children’s novel, The Governess, which was published in 1749 presents an educational practice that lays emphasis on improving students’ interpretative skills, especially of girls, in the eighteenth century. It alienates itself from the early eighteenth century educational ideas of Mary Astell and the later religious educational ideas of Hannah More. The Governess, which is also considered to be the first book in the genre of children’s literature, encapsulates the ideas of philosophers such as John Locke and the Bluestocking Elizabeth Montagu on good education and presents them in a much simplified form to her readers. Like Montagu, Sarah Fielding uses fairy tales, fictional autobiographies, fables and dramatic plays to communicate her message and asks her readers to interpret the actions of these characters for learning important morals. It is the induction of such genres of literature (fairy tales, plays) into the education of children which distinguish her novel from the complex and lengthy educational tracts of other prominent thinkers mentioned above, and which help us in understanding how teaching children to critically interpret the books they read strengthens the foundation of their intellectual development.