bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparative transcriptomic profiling of peripheral efferent and afferent nerve fibres at different developmental stages in mice
Authors: Wang Hongkui , Zhou Youlang , Cong Meng , Zhang Li , Gu Xiaosong , Tang Xin
Published: August 2018

Peripheral nerve injury impairs motor and sensory function in humans, and its functional recovery largely depends on the axonal outgrowth required for the accurate reinnervation of appropriate targets. To better understand how motor and sensory nerve fibres select their terminal pathways, an unbiased cDNA microarray analysis was conducted to examine differential gene expression patterns in peripheral efferent and afferent fibres at different developmental stages in mice. Gene ontology (GO) and Kyoto Enrichment of Genes and Genomes (KEGG) analyses revealed common and distinct features of enrichment for differentially expressed genes during motor and sensory nerve fibre development. Ingenuity Pathway Analysis (IPA) further indicated that the key differentially expressed genes were associated with trans-synaptic neurexin-neuroligin signalling components and a variety of gamma-aminobutyric acid (GABA) receptors. The aim of this study was to generate a framework of gene networks regulated during motor and sensory neuron differentiation/maturation. These data may provide new clues regarding the underlying cellular and molecular mechanisms that determine the intrinsic capacity of neurons to regenerate after peripheral nerve injury. Our findings may thus facilitate further development of a potential intervention to manipulate the therapeutic efficiency of peripheral nerve repair in the clinic.
On detection of periodicity in C-reactive protein (CRP) levels
Authors: Dorraki Mohsen , Fouladzadeh Anahita , Salamon Stephen J. , Allison Andrew , Coventry Brendon J. , Abbott Derek
Published: August 2018

C-reactive protein (CRP) is an acute-phase plasma protein that can be used as a biomarker for activation of the immune system. A spectral analysis of CRP level over time for patients with gynaecological tumours has been reported by Madondo et al., using a periodogram method, suggesting that there is no significant periodicity in the data. In our study, we investigate the impact of low sample number on periodogram analysis, for non-uniform sampling intervals—we conclude that data of Madondo et al. cannot rule out periodic behaviour. The search for patterns (periodic or otherwise) in the CRP time-series is of interest for providing a cue for the optimal times at which cancer therapies are best administered. In this paper we show (i) there is no evidence to rule out periodicity in CRP levels, and (ii) we provide a prescription for the minimum data sample rate required in future experiments for improved testing of a periodic CRP signal hypothesis. The analysis we provide may be used for establishing periodicity in any short time-series signal that is observed without a priori information.
Topological structures are consistently overestimated in functional complex networks
Authors: Zanin Massimiliano , Belkoura Seddik , Gomez Javier , Alfaro César , Cano Javier
Published: August 2018

Functional complex networks have meant a pivotal change in the way we understand complex systems, being the most outstanding one the human brain. These networks have classically been reconstructed using a frequentist approach that, while simple, completely disregards the uncertainty that derives from data finiteness. We provide here an alternative solution based on Bayesian inference, with link weights treated as random variables described by probability distributions, from which ensembles of networks are sampled. By using both statistical and topological considerations, we prove that the role played by links’ uncertainty is equivalent to the introduction of a random rewiring, whose omission leads to a consistent overestimation of topological structures. We further show that this bias is enhanced in short time series, suggesting the existence of a theoretical time resolution limit for obtaining reliable structures. We also propose a simple sampling process for correcting topological values obtained in frequentist networks. We finally validate these concepts through synthetic and real network examples, the latter representing the brain electrical activity of a group of people during a cognitive task.
Dose-dependent reversal of KCC2 hypofunction and phenobarbital-resistant neonatal seizures by ANA12
Authors: Carter B. M. , Sullivan B. J. , Landers J. R. , Kadam S. D.
Published: August 2018

Neonatal seizures have an incidence of 3.5 per 1000 newborns; while hypoxic-ischemic encephalopathy (HIE) accounts for 50–60% of cases, half are resistant to 1st-line anti-seizure drugs such as phenobarbital (PB). Tyrosine receptor kinase B (TrkB) activation following ischemic injury is known to increase neuronal excitability by downregulation of K-Cl co-transporter 2 (KCC2); a neuronal chloride (Cl−) co-transporter. In this study, three graded doses of ANA12, a small-molecule selective TrkB antagonist, were tested in CD1 mice at P7 and P10 following induction of neonatal ischemia by a unilateral carotid ligation. The PB loading dose remained the same in all treatment groups at both ages. Evaluation criteria for the anti-seizure efficacy of ANA12 were: (1) quantitative electroencephalographic (EEG) seizure burden and power, (2) rescue of post-ischemic KCC2 and pKCC2-S940 downregulation and (3) reversal of TrkB pathway activation following ischemia. ANA12 significantly rescued PB resistant seizures in a dose-dependent manner at P7 and improved PB efficacy at P10. Additionally, female pups responded better to lower doses of ANA12 compared to males. ANA12 significantly reversed post-ischemic KCC2 downregulation and TrkB pathway activation at P7 when PB alone was inefficacious. Rescuing KCC2 hypofunction may be critical for preventing emergence of refractory seizures.
Cobalamin-dependent radicalS-adenosyl-l-methionine enzymes in natural product biosynthesis
Authors: Wang Susan C.
Published: August 2018

This highlight examines the functions of cobalamin-dependent radicalS-adenosyl-l-methionine enzymes that catalyse chemically-challenging reactions in several bacterial natural product biosynthetic pathways.
Self-assembly of Au@Ag core–shell nanocubes embedded with an internal standard for reliable quantitative SERS measurements
Authors: Lin Shuang , Lin Xiang , Liu Yuanlan , Zhao Haiyan , Hasi Wuliji , Wang Li
Published: August 2018

Self-assembled Au@Ag nanocubes embedded with 4-MBA as an internal reference were applied for quantitative SERS measurements of aspartame in drinks.
Predicting the binding affinities of compound–protein interactions by random forest using network topology features
Authors: Li Zhanchao , Wang Yang , Xie Yun , Zhang Li , Dai Zong , Zou Xiaoyong
Published: August 2018

A predictor is proposed for the binding affinity of compound–protein interactions by constructing a comprehensive interaction network incorporating topology features.
Cu2+ modulated DNA-templated silver nanoclusters as a turn-on fluorescence probe for the detection of quinolones
Authors: Wang Renjun , Yan Xiaolu , Sun Jing , Wang Xiao , Zhao Xian-En , Liu Wei , Zhu Shuyun
Published: August 2018

In this contribution, DNA-templated silver nanoclusters (DNA-AgNCs) were successfully utilized as novel fluorescent probes for the detection of quinolones for the first time.
De novo design of small molecule acceptors via fullerene/non-fullerene hybrids for polymer solar cells
Authors: Zhao Yuan , Luo Zhenghui , Li Guanghao , Luo Jiajia , Zhang Zhi-Guo , Li Yongfang , Yang Chuluo
Published: August 2018

Fullerene and non-fullerene hybrids were designed and synthesized for polymer solar cells as small molecule acceptors.
The environmental stability of large-size and single-crystalline antimony flakes grown by chemical vapor deposition on SiO2 substrates
Authors: Wu Qinke , Song Young Jae
Published: August 2018

The environmental stability of large-sized and single-crystalline antimony flakes was systematically investigated with temperature and time dependence at fixed humidity.
Thermal-exfoliated synthesis of N-rich carbon-based nanosheets from layered bulk crystals of a metal–hexamine framework
Authors: Liu Sitong , Zhou Jisheng , Song Huaihe
Published: August 2018

2D N-rich carbon-based nanomaterials are succesfully prepared through the thermal exfoliation of layered metal–hexamine framework microcrystals.
A light-triggered transmembrane porin
Authors: Kahlstatt J. , Reiß P. , Halbritter T. , Essen L.-O. , Koert U. , Heckel A.
Published: August 2018

Porins are ideal model systems for channel engineering. Here, we present a photocaged diethylaminocoumarin (DEACM) hybrid of the transmembrane porin OmpG.
Ultrasensitive profiling of multiple biomarkers from single cells by signal amplification mass spectrometry
Authors: Wang Yuning , Du Ruijun , Qiao Liang , Liu Baohong
Published: August 2018

A mass spectrometry (MS) signal amplification method was developed to recognize simultaneously multiple biomarkers from a single cell.
Approaching single DNA molecule detection with an ultrasensitive electrochemical genosensor based on gold nanoparticles and cobalt-porphyrin DNA conjugates
Authors: Kaur Balwinder , Malecka Kamila , Cristaldi Domenico A. , Chay Clarissa S. , Mames Iwona , Radecka Hanna , Radecki Jerzy , Stulz Eugen
Published: August 2018

An ultrasensitive genosensor is obtained by using gold nanoparticles and cobalt-porphyrin labelled DNA reporter strands with an attomolar detection limit.
Unexpected behaviour in derivatives of Barluenga's reagent, Hal(Coll)2X (Coll = 2,4,6-trimethyl pyridine, collidine; Hal = I, Br; X = PF6, ClO4& BF4)
Authors: Morgan Lewis C. F. , Kim Yejin , Blandy Jack N. , Murray Claire A. , Christensen Kirsten E. , Thompson Amber L.
Published: August 2018

Attempts to study “diffuse modulation” in Br(Coll)2ClO4have shown that these non-Bragg features disappear very rapidly on exposure to synchrotron radiation, an observation that has implications for those using X-rays as a probe.
Li dopant induces moisture sensitive phase degradation of an all-inorganic CsPbI2Br perovskite
Authors: Li Yihui , Wang Yong , Zhang Taiyang , Yoriya Sorachon , Kumnorkaew Pisist , Chen Sujie , Guo Xiaojun , Zhao Yixin
Published: August 2018

The Li-TFSI dopant in hole transfer layers deteriorates the phase degradation of α-CsPbI2Br perovskites under ambient conditions.
The thermo-responsive behavior in molecular crystals of naphthalene diimides and their 3D printed thermochromic composites
Authors: Dharmarwardana Madushani , Arimilli Bhargav S. , Luzuriaga Michael A. , Kwon Sunah , Lee Hamilton , Appuhamillage Gayan A. , McCandless Gregory T. , Smaldone Ronald A. , Gassensmith Jeremiah J.
Published: August 2018

Alteration of the number of carbon atoms on the alkoxyphenyl substituent in naphthalene diimides results in tunable thermo-salient behavior.
Effect of basicity on the crystallization behavior of TiO2–CaO–SiO2 ternary system slag
Authors: Fan Gangqiang , Dang Jie , Lv Xuewei , Hu Meilong
Published: August 2018

The crystallization behavior of the TiO2–CaO–SiO2 system was investigated theoretically and experimentally in the binary basicity range from 1.0 to 1.4.
Kinetic studies of C1 and C2 Criegee intermediates with SO2 using laser flash photolysis coupled with photoionization mass spectrometry and time resolved UV absorption spectroscopy
Authors: Howes N. U. M. , Mir Z. S. , Blitz M. A. , Hardman S. , Lewis T. R. , Stone D. , Seakins P. W.
Published: August 2018

Kinetics of CH2OO + SO2 confirmed over a wide range of [SO2]. Acetaldehyde observed as a major product of the reaction of CH3CHOO + SO2.
Probing acid sites in solid catalysts with pyridine UV-Vis spectroscopy
Authors: Velthoen Marjolein E. Z. , Nab Sophie , Weckhuysen Bert M.
Published: August 2018

Pyridine UV-Vis spectroscopy is a promising acidity probing method, signified by its unique ability to distinguish different surface hydroxyl groups.
From quantum fragments to Lewis structures: electron counting in position space
Authors: Martín Pendás A. , Francisco E.
Published: August 2018

From quantum atoms to electron counting the rs-AdNCP strategy: a Lewis structure through (nc,2e) functions.
Two-dimensional transistors beyond graphene and TMDCs
Authors: Liu Yuan , Duan Xidong , Huang Yu , Duan Xiangfeng
Published: August 2018

We present an overview of the recent advances in two-dimensional transistors beyond graphene and transition metal dichalcogenides.
Unique physicochemical properties of two-dimensional light absorbers facilitating photocatalysis
Authors: Liu Gang , Zhen Chao , Kang Yuyang , Wang Lianzhou , Cheng Hui-Ming
Published: August 2018

The emergence of two-dimensional (2D) materials with a large lateral size and extremely small thickness has significantly changed the development of many research areas by producing a variety of unusual physicochemical properties.
2D and 3D mixed MII/CuIImetal–organic frameworks (M = Ca and Sr) withN,N′-2,6-pyridinebis(oxamate) and oxalate: preparation and magneto-structural study
Authors: Fernandes Tamires S. , Melo Wanessa D. C. , Kalinke Lucas H. G. , Rabelo Renato , Valdo Ana K. , da Silva Cameron C. , Martins Felipe T. , Amorós Pedro , Lloret Francesc , Julve Miguel , Cangussu Danielle
Published: August 2018

Heterobimetallic coordination polymers with either antiferro- of ferromagnetic interactions are described herein.
A methodical selection process for the development of ketones and esters as bio-based replacements for traditional hydrocarbon solvents
Authors: Byrne Fergal P. , Forier Bart , Bossaert Greet , Hoebers Charly , Farmer Thomas J. , Hunt Andrew J.
Published: August 2018

A “top down” approach to the development of sustainable, greener, low-polarity solvents is presented.
Single-molecule tracking in liveYersinia enterocoliticareveals distinct cytosolic complexes of injectisome subunits
Authors: Rocha Julian Michael , Richardson Charles Joseph , Zhang Mingxing , Darch Caroline Maureen , Cai Eugene , Diepold Andreas , Gahlmann Andreas
Published: August 2018

Single-molecule tracking of bound (blue trajectories) and diffusive (red trajectories) injectisome subunits reveals the formation of distinct cytosolic complexes.
Biotransformation of organic selenium compounds in budding yeast,Saccharomyces cerevisiae
Authors: Ogra Yasumitsu , Shimizu Maya , Takahashi Kazuaki , Anan Yasumi
Published: August 2018

Organic selenium metabolites of plants and animals such as selenoamino acids and selenosugars are metabolized to selenomethionine in yeast.
A 3D metal–organic framework with dual-aerial-octahedral trinucleate building units: synthesis, structure and fluorescence sensing properties
Authors: Zhao Yan-Ning , Zhang Shu-Ran , Wang Wei , Xu Yan-Hong , Che Guang-Bo
Published: August 2018

JLNU-2 can be used to detect nitrobenzene with high selectivity, sensitivity, anti-interference ability and recyclability through tracing the fluorescence quenching behaviour.
A NBD-S-rhodamine dyad for dual-color discriminative imaging of biothiols and Cys/Hcy
Authors: Sun Lu , Jiang Yaqing , Zhang Changyu , Ji Xiuru , Lv Dequn , Xi Zhen , Yi Long
Published: August 2018

A fluorescent probe based on fast thiolysis of NBD thioether is developed for dual-color discriminative imaging of Cys and GSH.
Facile synthesis of a hierarchical CuS/CuSCN nanocomposite with advanced energy storage properties
Authors: Kannangara Yasun Y. , Prabunathan Pichaimani , Song Jang-Kun
Published: August 2018

Facile fabrication of a CuS/CuSCN nanocomposite electrode for a supercapacitor with a high specific capacitance (1787.3 F g−1).
Lithium titanate anode for high-performance lithium-ion batteries using octadecylamine and folic acid-functionalized graphene oxide for fabrication of ultrathin lithium titanate nanoflakes and modification of binder
Authors: Youjie Li , Li Ruiyi , Yang Yongqiang , Li Zaijun
Published: August 2018

Functionalized graphene oxide creates significant improvement in electrochemical performance of lithium titanate anode due to high conductivity and structural stability.
Stretchable thin-film transistors with molybdenum disulfide channels and graphene electrodes
Authors: Park Ick-Joon , Kim Tae In , Kang Sumin , Shim Gi Woong , Woo Youngjun , Kim Taek-Soo , Choi Sung-Yool
Published: August 2018

Stretchable MoS2 transistors with graphene electrodes are proposed for basic building blocks enabling the creation of 2D materials-based stretchable displays.
Bi2O3 monolayers from elemental liquid bismuth
Authors: Messalea Kibret A. , Carey Benjamin J. , Jannat Azmira , Syed Nitu , Mohiuddin Md , Zhang Bao Yue , Zavabeti Ali , Ahmed Taimur , Mahmood Nasir , Della Gaspera Enrico , Khoshmanesh Khashayar , Kalantar-Zadeh Kourosh , Daeneke Torben
Published: August 2018

Atomically thin layers of Bi2O3 are isolated from liquid bismuth, allowing the development of ultrafast 2D-enabled UV photo-detectors.
Room-temperature surface-assisted reactivity of a melanin precursor: silver metal–organic coordination versus covalent dimerization on gold
Authors: De Marchi F. , Galeotti G. , Simenas M. , Tornau E. E. , Pezzella A. , MacLeod J. , Ebrahimi M. , Rosei F.
Published: August 2018

The surface drives the self-assembly of a catechol–indole molecule, triggering metal–organic coordination on silver and dimerization on gold at room temperature.
Ultralow-fluence single-shot optical crystalline-to-amorphous phase transition in Ge–Sb–Te nanoparticles
Authors: Casarin Barbara , Caretta Antonio , Chen Bin , Kooi Bart J. , Ciprian Roberta , Parmigiani Fulvio , Malvestuto Marco
Published: August 2018

Ge2Sb2Te5 crystalline nanoparticles amorphize through a single laser pulse with exceptional low fluence, boosting the energetics of a phase-change process.
Solid-state nanocasting synthesis of ordered mesoporous CoNx–carbon catalysts for highly efficient hydrogenation of nitro compounds
Authors: Wei Xiangru , Zhang Zhujun , Zhou Mengyuan , Zhang Aijian , Wu Winston Duo , Wu Zhangxiong
Published: August 2018

A solid-state nanocasting approach is developed for the synthesis of ordered mesoporous CoNx–carbon catalysts with outstanding catalytic activity, selectivity and stability for the hydrogenation of nitro compounds in aqueous solutions.
Recent developments in functionalization of acyclic α-keto amides
Authors: Muthukumar Alagesan , Sangeetha Subramani , Sekar Govindasamy
Published: August 2018

This review describes the synthetic utility of α-keto amides to synthesize various important molecules via mono, dual and triple functionalization reactions.
2-Picoline catalyst-triggered [2 + 2 + 2] cycloaddition-type reaction of acetylenedicarboxylates, aldehydes and alkenes
Authors: Tateishi Keiichiro , Noguchi Keiichi , Saito Akio
Published: August 2018

2-Picoline efficiently catalyzes the formation of α,β-enones from acetylenedicarboxylates and aldehydes in the presence of alkenes, thereby leading to pyrans with complete regioselectivities. This method is represented as a first example of catalytic and metal-free [2 + 2 + 2] cycloaddition of three different components.
Poly(2-methacryloyloxyethyl phosphorylcholine)-based biodegradable nanogels for controlled drug release
Authors: Xie Ruihong , Tian Yefei , Peng Shaojun , Zhang Liren , Men Yongzhi , Yang Wuli
Published: August 2018

We developed reduction degradable PMPC nanogels for controlled drug releaseviaprecipitation polymerization using a disulfide-containing crosslinker.
Fluorescent sensors based on AIEgen-functionalised mesoporous silica nanoparticles for the detection of explosives and antibiotics
Authors: Wang Chen , Li Qinglan , Wang Bolun , Li Dongdong , Yu Jihong
Published: August 2018

AIEgen-functionalised mesoporous silica nanoparticles can be used for the detection of explosives and antibiotics based on a FRET mechanism.
Fabrication of Ag3PO4/GO/NiFe2O4 composites with highly efficient and stable visible-light-driven photocatalytic degradation of rhodamine B
Authors: Zhou Tianhong , Zhang Guozhen , Yang Hao , Zhang Hongwei , Suo Ruini , Xie Yingshuang , Liu Gang
Published: August 2018

Effective visible-light-driven Ag3PO4/GO/NiFe2O4Z-scheme magnetic composites were successfully fabricated by a simple ion-exchange deposition method. The composites exhibited excellent photocatalytic activity and stability for RhB degradation.
Halogen bonding for the design of inhibitors by targeting the S1 pocket of serine proteases
Authors: Jiang Longguang , Zhang Xu , Zhou Yang , Chen Yayu , Luo Zhipu , Li Jinyu , Yuan Cai , Huang Mingdong
Published: August 2018

BrBA binds to the S1 pocket of urokinase with Br facing the base of the pocket by halogen bonds, while iodine of IBA binds to the S1 in the opposite way.
Infrared microlenses and gratings of chalcogenide: confined self-organization in solution processed thin liquid films
Authors: Sachan Priyanka , Singh Radhakant , Dwivedi Prabhat K. , Sharma Ashutosh
Published: August 2018

Directed self-organization of a glassy material is demonstrated to generate ultra smooth, optically useful micro structures such as lens arrays and gratings. Liquid thin films of chalcogenide re-organize within the confinement provided by the mould.
Synthesis of β-alkoxy-N-protected phenethylamines via one-pot copper-catalyzed aziridination and ring opening
Authors: Saavedra-Olavarría Jorge , Madrid-Rojas Matías , Almodovar Iriux , Hermosilla-Ibáñez Patricio , Pérez Edwin G.
Published: August 2018

An efficient, regioselective and rapid copper-catalyzed one-pot aminoalkoxylation of styrenes has been developed using different alcohols and phenyl iminoiodinanes.
Incorporation of antimicrobial peptides on electrospun nanofibres for biomedical applications
Authors: Amariei Georgiana , Kokol Vanja , Boltes Karina , Letón Pedro , Rosal Roberto
Published: August 2018

The aim of this work was to immobilize antimicrobial peptides onto a fibrous scaffold to create functional wound dressings.
Adsorption characteristics of Cd(ii) in aqueous solutions using spent mushroom substrate biochars produced at different pyrolysis temperatures
Authors: Xian Yang , Wu Jun , Yang Gang , Liao Ruiting , Zhang Xiaohong , Peng Hong , Yu Xiaoyu , Shen Fei , Li Li , Wang Lilin
Published: August 2018

To effectively remove Cd from water, biochars were produced by pyrolyzing SMS. And the adsorption characteristics of Cd(ii) using SMS biochars was studied.
Skin cancer detection using non-invasive techniques
Authors: Narayanamurthy Vigneswaran , Padmapriya P. , Noorasafrin A. , Pooja B. , Hema K. , Firus Khan Al'aina Yuhainis , Nithyakalyani K. , Samsuri Fahmi
Published: August 2018

Recent advances in non-invasive techniques for skin cancer diagnosis.
A review of the interfacial characteristics of polymer nanocomposites containing carbon nanotubes
Authors: Chen Junjie , Liu Baofang , Gao Xuhui , Xu Deguang
Published: August 2018

The state of research on the characteristics at the interface in polymer nanocomposites is reviewed. Special emphasis is placed on the recent advances in the fundamental relationship between interfacial characteristics and nanocomposite properties.
Theoretical investigation of the effects of various substituents on the large energy gap between triplet excited-states of anthracene
Authors: Dawei Yu , Xiaojuan Zhang , Zhiming Wang , Bing Yang , Yuguang Ma , Yuyu Pan
Published: August 2018

The utilization of excitons is key to the effectiveness of organic electroluminescent materials.
Evaluation of anti α-d-Glcp-(1→4)-α-d-Glcp (GAGA4) IgM antibodies as a biomarker for multiple sclerosis
Authors: Braganza Chriselle D. , Santoso Kristiana T. , Dangerfield Emma M. , La Flamme Anne C. , Timmer Mattie S. M. , Stocker Bridget L.
Published: August 2018

Anti-glucose IgM antibodies are not upregulated in RRMS patients and thus are not a suitable biomarker for MS.
Formation of nanopores in DiynePC–DPPC complex lipid bilayers triggered by on-demand photo-polymerization
Authors: Chun Min Jung , Choi Yeol Kyo , Ahn Dong June
Published: August 2018

Nanopores generated upon photo-polymerization of the lipid membrane containing DiynePC were identified and their size was controllable.
Asymmetric ring-opening reaction of meso-epoxides with aromatic amines using homochiral metal–organic frameworks as recyclable heterogeneous catalysts
Authors: Tanaka Koichi , Kinoshita Maya , Kayahara Jun , Uebayashi Yutaro , Nakaji Kazusada , Morawiak Maja , Urbanczyk-Lipkowska Zofia
Published: August 2018

Asymmetric ring-opening reactions of meso-epoxides by aromatic amines were achieved by using some chiral metal–organic frameworks. The corresponding β-amino alcohols were obtained with good yields and enantioselectivities (up to 97% ee).
Development of a high-throughput and sensitive assay of fusion genes in lung cancer by array-based MALDI-TOFMS
Authors: Wu Han-Tao , Li Kun , Wang Gang , Yang Xue-Xi , Zhu Anna , Xu Xu-Ping , Li Ming , Wu Ying-Song , Liu Tian-Cai
Published: August 2018

This study established a high-throughput, sensitive and cost-effective method to detect three lung fusion genes of 96 samples at one time.
Proximity hybridization triggered strand displacement and DNAzyme assisted strand recycling for ATP fluorescence detection in vitro and imaging in living cells
Authors: Gao Fenglei , Wu Jing , Yao Yao , Zhang Yu , Liao Xianjiu , Geng Deqin , Tang Daoquan
Published: August 2018

A novel strategy for ATP imaging was developed based on proximity binding-induced strand displacement and metal ion-dependent DNAzyme recycling.
Dual pH-sensitive and UCST-type thermosensitive dendrimers: phenylalanine-modified polyamidoamine dendrimers with carboxyl termini
Authors: Tamaki Mamiko , Fukushima Daichi , Kojima Chie
Published: August 2018

We designed carboxyl-terminal Phe-modified PAMAM dendrimers by using various acid anhydrides. These dendrimers exhibited UCST-type thermosensitivity, which was dependent on both pH and the anhydride modifier.
Discovery of asymmetric NaXBi (X= Sn /Pb) monolayers with non-trivial topological properties
Authors: Jia Yi-zhen , Ji Wei-xiao , Zhang Chang-wen , Li Ping , Wang Pei-ji
Published: August 2018

Based on density functional theory (DFT) calculations, we propose a new type of 2D asymmetric NaXBi (X = Sn and Pb) monolayer, which can realize the coexistence of a topological phase and the Rashba effect.
Valorization of papaya fruit waste through low-cost fractionation and microbial conversion of both juice and seed lipids
Authors: Han Zhenlin , Park Alex , Su Wei Wen
Published: August 2018

Seed oil from papaya waste was validated as a novel carbon substrate for Yarrowia lipolytica to produce high-value products.
Length-independent charge transport of well-separated single-crystal TiO2 long nanowire arrays
Authors: Liu Jie , Sheng Xia , Guan Fengying , Li Ke , Wang Dandan , Chen Liping , Feng Xinjian
Published: August 2018

Vertically aligned and well-separated single-crystal TiO2 NW arrays with a length of up to ∼10 μm were synthesized via a simple solvothermal method. The charge transport in these NWs is over 100 times faster than that of nanoparticle films and remarkably exhibits length-independence.
Effect of geometry on the dewetting of granular chains by evaporation
Authors: Cejas Cesare M. , Hough Lawrence A. , Frétigny Christian , Dreyfus Rémi
Published: August 2018

Meniscus stability depends on grain arrangement, whose geometry is defined by a packing angle. Smaller angles have stable menisci.
Biomimetic super durable and stable surfaces with superhydrophobicity
Authors: Jing Xueshan , Guo Zhiguang
Published: August 2018

A detailed introduction to superhydrophobic surfaces with superior durability characteristics and comprehensive discussion about fabrication approaches to prolong surface lifetimes are presented in this review, which is expected to inspire a number of scholars to fabricate more durable superhydrophobic materials.
Composition effect of alloy semiconductors on Pt-tipped Zn1−xCdxSe nanorods for enhanced photocatalytic hydrogen generation
Authors: Choi Ji Yong , Nam Ki Min , Song Hyunjoon
Published: August 2018

The light absorption and electron mobility of alloy semiconductors significantly influenced the photocatalytic hydrogen evolution of Pt-tipped Zn1−xCdxSe nanorods.
Highly conductive and stabilized side-chain-type anion exchange membranes: ideal alternatives for alkaline fuel cell applications
Authors: Ran Jin , Ding Liang , Chu Chengquan , Liang Xian , Pan Ting , Yu Dongbo , Xu Tongwen
Published: August 2018

Two optional strategies for enhancing the hydroxide conductivity of conventional side-chain-type anion exchange membranes.
Cobalt and nitrogen-codoped ordered mesoporous carbon as highly efficient bifunctional catalysts for oxygen reduction and hydrogen evolution reactions
Authors: Liu Xiaojun , Li Wenyue , Zou Shouzhong
Published: August 2018

Co, N-codoped ordered mesoporous carbons showed excellent electrocatalytic activities for the ORR and HER.
Thermoelectric stability of Eu- and Na-substituted PbTe
Authors: Wang Xinke , Veremchuk Igor , Burkhardt Ulrich , Bobnar Matej , Böttner Harald , Kuo Chang-Yang , Chen Chien-Te , Chang Chun-Fu , Zhao Jing-Tai , Grin Yuri
Published: August 2018

The out-of-equilibrium samples show highest values of figure-of-merit, ZTmax, up to 2.1.
Study of Circulation Drive in High-Speed Rotating Flow Field
Authors: Fan Xu , Ran Bo
Published: August 2018

In the rotor with high speed, there is a certain axial circulation in the internal gas, which is necessary to analyze the cause of formation and influence factors for understanding better the internal flow field. There are many factors affecting the axial circulation. Different circulation drives have different effects on the flow field. In this paper, numerical computation with N-S equations is used to compute the flow field parameters and analyze the mechanism of the flow field. The influence of the temperature of the end cap on the flow field is mainly disscussed. By comparing and analyzing the streamline shape and the size of vortex region under different temperature drive, an effective method is provided for the study of axial circulation in the highspeed rotating flow field.
Electromagnetic Radiation from the Geometrical Point of View
Authors: Dmitriy Divakov , Mikhail Malykh , Anastasiia Tiutiunnik
Published: August 2018

The article describes the relationship between the solutions of Maxwell's equations which can be considered at least locally as plane waves and the curvilinear coordinates of geometrical optics. We introduce phase-ray coordinate system for any electromagnetic field if vectors E and H are orthogonal to each other and their directions do not change with time t, but may vary from point to point in the domain G.
Effect of Shear Deformation on Texture Evolution in Rolled Pure Titanium
Authors: Yang Huanping , Wang Yaomian
Published: August 2018

The cold rolling texture evolution under different strain states caused by coupled effects from different combinations of roll gap geometry and friction in pure titanium with initial typical recrystallized texture has been studied using viscoplastic self-consistent simulations. Under plane strain state, the texture is dominated by a typical cold rolling fiber texture RD//<1010> in pure titanium. However, when shear deformation is induced and increased, RD//<1010> fiber texture is decreased, whereas basal texture (0001)[1010] is increased and a strong partial fiber texture RD//<2110> is formed. The variation of cold rolling texture at different strain states can be ascribed to variation of relative contribution from activation of prismatic, basal and pyramidal slip.
Strength Development and Microstructure of Alkali-activated Slag-MgO in Air Curing Condition
Authors: Hwang Chao-Lung , Vo Duy-Hai , Yehualaw Mitiku Damtie , Tran Vu-An
Published: August 2018

The aim of this study is to analysis the effect of MgO on strength development and microstructure of alkali-activated slag (AAS) in air curing condition. Four mixtures of AAS are prepared using different MgO content (0%, 5%, 10%, and 15 % by weight of slag) at water to binder ratio of 0.4. The flow, compressive strength, scanning electron microscopy, and X-ray diffraction are tested under relevant standards. The addition of MgO significantly accelerated the hydration rate of AAS. AAS with adding MgO tended to increase the compressive strength and to reduce the flow. The higher adding MgO content was associated with higher hydrotalcite-like phase (Ht) formation which improved the microstrure of AAS in the air curing condition.
Chemical Profiling Analysis and Identification the Bioactivities of Herbal Compress Extracts
Authors: Chotikamas Sumitta , Cheenkachorn Kraipat , Wongpanit Boochita , Tantayotai Prapakorn , Sriariyanun Malinee
Published: August 2018

The traditional Thai herbal compress is composed of six different types of herbs including Ginger (Zingiber cassumunar), Turmeric (Curcuma longa Linn.), Soap Pod (Acacia concinna), Kaffir lime (Citrus hystrix), Lemongrass (Cymbopogon citratus), and Tamarind (Tamarindus indica Linn.). Herbal compress is used in treatment of Thai traditional massage to relieve the body pain and muscle strains. The objective of this work is to perform chemical profiling and extraction modelling of herbal compress obtained from solvent extraction method. The kinetic models, The second order and Fick‘s second law, representing the extraction behaviors of bioactive compounds were constructed to fit with experimental data of solvent extraction. Under tested condition, the extraction equilibrium was reached after 360 min and the second-order model gives the best fit for the experimental data with high coefficients of correlation (R2 = 0.9927). Additionally, chemical profiling analysis showed that the amounts and variations of bioactive components in drying-pretreated herbal compress were more abundant than that of untreated sample. This finding could be applied further for preparation and production of traditional Thai herbal compress in the industrial scale.
Preparation of Microcrystalline Cellulose from Water Hyacinth Reinforced Polylactic Acid Biocomposite
Authors: Semachai Teerapa , Chandranupap Panitnad , Chandranupap Pravitra
Published: August 2018

In this work, we successfully mixed polylactic acid (PLA) with microcrystalline cellulose (MCC) from water hyacinth. The MCC was prepared by treating water hyacinth fiber (WHF). Then hydrochloric acid was used to hydrolyze treated fiber to MCC. X-rays diffraction (XRD) showed that the MCC produced has 73.28 per cent crystallinity. Internal mixing was used to combine composites between MCC and PLA. Percentages of MCC were 1, 5, 10 and 15, respectively. Fourier transform infrared (FT-IR) spectroscopy indicated that the interaction between MCC and PLA are only mechanically interaction. Tensile testing of this composite (ASTM D638) revealed that tensile strength and percentage of elongation at break decreased but the increase of young's modulus. The morphological analysis was observed thru composites fractured surface by Scanning Electron Microscope (SEM). They showed a void between cellulosic fiber and PLA when high amount of MCC conformed with tensile results.
Strategies for Promoting Steelmaking Slag Resourcezation in Taiwan
Authors: Chang Ching-Jung
Published: August 2018

Because of the world ever-growing pursuit of economic growth, natural resources have been overly exploited and squandered. Such actions have created a negative effect on the environment and led to resource depletion. These problems subsequently garnered the government attention for waste reuse, in which they began to promote sustainable circulation and reuse of resources to lower natural resource consumptions. Accordingly, the concept of the "3 R's," namely, reduce, recycle, and reuse was introduced. However, the said concept merely adopts a unidirectional, cradle-to-grave-based treatment and fails to consider the effects of waste on the economy and society. Taiwan produces approximately 20 million tonne s of waste annually, roughly 40% of which are slags. The illegal dumping and burying of slags have negatively influenced Taiwan's environment, economy, and society. Thus, the present study revolutionized the 3R concept by introducing the cradle to cradle concept. Producers are recommended to consider product features and slag usage options during the steelmaking process. Transparent productions, effective management, scientific treatments, and systematic inspections are employed to bring slags into industrial circulations, facilitating the recycling and reuse of resources.
Syngas from Updraft Gasifier Incineration for Internal Combustion Engine Power Generation in Klongluang PathumThani Thailand
Authors: Sookramoon Krissadang
Published: August 2018

This paper presents the internal combustion engine power generation using syngas from the updraft biomass gasifier as a fuel. 3 types of fuel such as Golden shower tree wood chip, charcoal, and gasohol 91 were tested for the engine running. The experiment was performed on July 25-26, 2017 at Faculty of Industrial Technology Vallaya Alongkorn Rajabhat University Pathum Tani Thailand. Data on the performance of the engines fueled with producer gas and gasohol 91 is presented. The experiment was carried out by using a four-stroke 13 HP gasoline engine coupled with a generator as a load in producing electricity. The carburetor was modified for fuel gas running by loading 7 kg/batch of Golden shower chips and charcoal for syngas producing and the engine performance was measured. The results showed that, the engine power was 110.125 W, 115.425 W, and 128.038 W, while using a golden shower chip, charcoal, and gasohol 91 as the fuel, respectively. The generator efficiency is 80% therefore the generator power reduces 20%. The test indicated that golden shower chips could produce higher quality of syngas than charcoal but the engine power has less power than fueled with gasohol 91.
A Novel Global Warming Solution: Use of Flue Gas to Produce Urea
Authors: AlDhaheri Zaina , Aysha Ajish Saniha , Rahman Sumaita , Owda Laila , AlNowahi Salma , Chaalal Omar
Published: August 2018

Urea is a nitrogenous organic compound which is widely used as a fertilizer and in the agricultural industry. On an industrial scale, urea can be manufactured from the reaction of carbon dioxide and ammonia. The goal of this research is to design a plant that produces 46.84 tons/hr of urea from the raw materials carbon dioxide and ammonia. The quantities of carbon dioxide and ammonia consumed in the process were 37.32 tons/hr and 28. 84 tons/hr, respectively. The carbon dioxide is obtained using a sustainable approach from the waste products, the flue gas, of a nearby power plant. In the first step of the process, carbon dioxide is extracted in an absorption column that uses ammonia and stripping columns from the flue gases emitted from a power plant. This ensures that the whole production process is environmentally sustainable and contributes to the reduction of carbon dioxide that cause global warming.
Linear Programming Model for the Measurement of Environmental Performance in Wine Industry—Concepts and Empirical Results
Authors: Chen Shiang , Wu Jung-Hua
Published: August 2018

In Taiwan we are currently facing serious air pollution problems, PM2.5 airborne particles not only endanger the human body, leading to coughing, asthma, chronic bronchial and other respiratory diseases, but it is also carcinogenic, our basic rights for survival has been seriously threatened. According to the latest study by the Environmental Protection Agency, the industrial sector accounts for about 25% of the sources of air pollution in Taiwan. The winemaking industry, with raw materials has several stages of production; it must use electricity, water, oil, diesel, gasoline, and steam as energy. The final product is not only wine, but also the discharge wastewater, lees, CO2, waste gas, etc. Different process methods will produce different energy consumption results, thus providing the possibility of CO2 reduction. This study takes the winemaking industry as a case study, trying to find out how to achieve a concept of “win-win situation “for both sides of carbon reduction and economy development. First, aiming at the policy of energy saving and carbon-reduction inventory of winery, trying to find out the source of pollution and the change of pollution source during 2008-2016, and then according to the data, the empirical results are analysed. Finally, a linear programming model proposed for the production planning of winemaking processes to achieve maximum operational profit while reducing CO2 emissions. The options considered in this research are levy the carbon tax in different prices to decrease CO2 emissions; installation of new equipment to enhance capacity; switching production schedule that emits less CO2. The objective of the linear programming model is to determine suitable CO2 mitigation options for a given reduction target while meeting the demand of each final product, quality specifications, and simultaneously maximizing profit. In this research, How to achieve the optimal production goals: minimizing the cost & energy consumption, and the maximum production value become the optimal production objection.
Analysis of Energy Consumption of Indonesian Flat Glass Industry PT. X Based on Green Industry Standards
Authors: Revitasari Reviana , Heru Susanto Bambang
Published: August 2018

The natural resource consumption is higher along with the increasing needs of people in various sectors, which affect the environment directly or indirectly. Especially for energy consumption, the supply and availability of fossil energy, as a non-renewable energy, are increasingly depleted and not guaranteed in the long run, coupled with the issue of emissions generated. The industrial sector as a driver of the national economy, including the flat glass industry as a case study, is an energy intensive sector. Almost 83% of its energy consumption used for operating the furnaces as the main production unit with temperature up to 1700 °C continuously about 15 years. The increasing of effectiveness and efficiency of energy consumption in the glass manufacturing process will affect significantly to sustainable production in PT. X and gives many other valuable impacts to the economic growth, environment, and society. So, this study analyzes about the energy consumption in PT. X based on Green Industry Standards, believed as a proper strategy, the benchmark of some standards or related regulations for energy consumption in several countries, and the opportunity of the green industry concept implementation in the glass manufacturing process. The methods were studied of literature, plant observation, interview, and data calculation manually and using spreadsheets. The results indicate that the Flat Glass Industry PT. X requires the improvement to increase the effectiveness and efficiency of energy consumption to get the sustainable production.
Scale-Up of Solid-Liquid Mixing Based on Constant Power/Volume and Equal Blend Time Using VisiMix Simulation
Authors: Megawati  , Triwibowo Bayu , Karwono  , Sammadikun Waliyuddin , Musfiroh Rofiatun
Published: August 2018

Mixing is one of the important process in many areas of chemical industries, for instance pharmaceutical, drug, ink, paint and other industries. Solid-liquid suspension is produced for 80% of all mixing industries such as leaching process, crystallization process, catalytic reactions, precipitation, coagulation, dissolution and other applications. Two main objectives in solid-liquid mixing namely, avoid settling of solid particles on the tank bottom and ensure the solid particles are uniformly distributed. Many factors that can affect the quality of solid-liquid mixing, they are tank geometry, impeller geometry and speed, baffles, viscosity and density of media. Scale-up of the process is important to conduct before produce it on commercial scale. Two parameters for scale-up solid-liquid mixing are equal blend time and power per volume. Before scaling up the process to industrial scale, an engineer must know the condition of the mixture between both of two. VisiMix can simulating scale-up of solid-liquid mixing in order to know the phenomena inside the tank without conducting a large number of experiments and cheaper. The simulation start from keep the ratio of impeller to tank diameter remains constant, then change the condition operation of mixing. In this paper, power per volume parameter is more recommended as a result of the degree of uniformity of solid phase in liquid.
Tonsillotomie verursacht weniger indirekte Kosten als Tonsillektomie
Authors: Dombrowski Tobias
Published: August 2018

Gudnadottir G et al. Indirect costs related to caregivers‘ absence from work after paediatric tonsil surgery. Eur Arch Otorhinolaryngol 2017; 275: 2629–2636. doi:10.1007/s00405–0174526–7

Bei Kindern mit schlafbezogenen Atemwegsobstruktionen durch vergrößerte Rachenmandeln hat die Tonsillotomie die Tonsillektomie heute weitgehend ersetzt. Vorteil könnte neben geringerer Schmerzen und kürzerer Rekonvaleszenzzeit auch eine Reduktion indirekter Kosten durch kürzere Arbeitsausfallzeiten der Eltern oder Betreuer sein. Dies wurde im Rahmen einer schwedischen Kohortenstudie untersucht.
Contrast-Enhanced Ultrasound (CEUS) Identifies Perfusion Differences Between Tibial Fracture Unions and Non-Unions
Authors: Fischer Christian , Haug Tabea , Weber Marc-Andre , Kauczor Hans-Ulrich , Bruckner Thomas , Schmidmaier Gerhard
Published: August 2018

Purpose To assess the value of CEUS in the evaluation of tibial fracture perfusion and its ability to differentiate between physiologic and abnormal fracture healing.

Materials and Methods From 2014 to 2017, 107 patients with tibial fractures or tibial non-unions underwent CEUS examination. CEUS was performed at the regular follow-up examination 26 weeks after osteosynthesis or before non-union surgery. Time-intensity curves (TICs) of the contrast enhancement in the fracture gap were generated, and volume parameters such as wash-in rate (WiR), peak enhancement (PE) and wash-in perfusion index (WiPI) were quantified.

Results A total of 34 patients met the inclusion criteria of this study, including 14 consolidated fractures, 12 aseptic non-unions and 8 infected non-unions. WiR, PE and WiPI showed significantly lower values in aseptic non-unions compared to unions (p = 0.009, 0.009, 0.012, resp.). In contrast, infected non-unions showed higher values of WiR, PE and WiPI when compared to unions (p = 0.034, 0.056, 0.029, resp.).

Conclusion CEUS represents a feasible method in the assessment of tibial fracture perfusion. Perfusion differences between aseptic and infected tibial non-unions as well as healing tibial fractures could be detected. The deviation of physiologic fracture perfusion seems to be associated with disturbed osseous regeneration leading to non-union.
Thyroid Autoimmunity and Thyroid Cancer – The Pathogenic Connection: A 2018 Update
Authors: Nagayama Yuji
Published: August 2018

The association between thyroid cancer and thyroid autoimmunity has long been suggested, but remains to be elucidated for several decades. Here the data on this issue are updated by summarizing relevant papers published between 2012 and early 2018. Although numerous papers demonstrated the significant increase in the prevalence of thyroid autoimmunity (positive intrathyroidal lymphocyte infiltration and/or anti-thyroglobulin/thyroid peroxidase antibodies) in patients with thyroid cancers as compared to those with benign nodules, and also the significant increase in the prevalence of papillary thyroid cancer (PTC) in patients with thyroid autoimmunity as compared to those without, there are some crucial biases that should be taken into account for their interpretation. However, a difference in the incidence of thyroid autoimmunity in patients with PTCs and those with other types of thyroid cancers appears to support the significant association of two conditions. Thyroid autoimmunity is, at least partly, likely to be elicited against antigens shared by normal and cancerous thyroid tissues, thereby inducing autoimmunity. At the same time, elevated TSH levels (even within the normal reference ranges), which often accompany Hashimoto’s patients are a risk factor for thyroid cancer. However, it is still unclear whether or not the co-existence of thyroid autoimmunity impacts on cancer characteristics and prognosis. This issue needs to be further investigated with large-scale prospective studies.