bluuebunny/crossref_metadata_2025 huggingface dataset:
IL-1 Receptor Antagonist Anakinra in the Treatment of COVID-19 Acute Respiratory Distress Syndrome: A Retrospective, Observational Study
Authors: Franzetti Marco , Forastieri Andrea , Borsa Noemi , Pandolfo Alessandro , Molteni Chiara , Borghesi Luca , Pontiggia Silvia , Evasi Giulia , Guiotto Lorenzo , Erba Mattia , Pozzetti Ugo , Ronchetti Anna , Valsecchi Letizia , Castaldo Gioacchino , Longoni Ernesto , Colombo Daniele , Soncini Marco , Crespi Stefano , Maggiolini Stefano , Guzzon Davide , Piconi Stefania
Published: February 2021

The IL-1 receptor antagonist, anakinra, may represent a therapeutic option for acute respiratory distress syndrome (ARDS) associated with coronavirus disease 2019 (COVID-19). In this study, COVID-19 ARDS patients admitted to the Azienda Socio Sanitaria Territoriale of Lecco, Italy, between March 5th to April 15th, 2020, and who had received anakinra off-label were retrospectively evaluated and compared with a cohort of matched controls who did not receive immunomodulatory treatment. The primary end point was survival at day 28. The population consisted of 112 patients (56 treated with anakinra and 56 controls). Survival at day 28 was obtained in 69 patients (61.6%) and was significantly higher in anakinra-treated patients than in the controls (75.0 versus 48.2%, p = 0.007). When stratified by continuous positive airway pressure support at baseline, anakinra-treated patients’ survival was also significant compared with the controls (p = 0.008). Univariate analysis identified anakinra usage (odds ratio, 3.2; 95% confidence interval, 1.47–7.17) as a significant survival predictor. This was not supported by multivariate modeling. The rate of infectious-related adverse events was similar between groups. In conclusion, anakinra improved overall survival and invasive ventilation-free survival and was well tolerated in patients with ARDS associated with COVID-19.
miR-26b regulates cell proliferation and apoptosis of CD117+CD44+ ovarian cancer stem cells by targeting PTEN
Authors: Gao Zubiao , Ye Xiaofeng , Bordeaux Anne , Hettich Stanka , Lin Siyao , Han Fang , Jia Yan
Published: February 2021

Ovarian cancer (OC) is the one of the most common cancer in women globally. However, it still represents the most dangerous gynecologic malignancy even with the advances in detection and therapeutics. Thus, there is an urgent need in finding more effective therapeutic options for OC patients including cancer stem cells (CSC). MicroRNAs (miRNAs) are small, endogenous, and non-coding RNAs that play critical roles in the progression of various types of tumor. Our aim of this study was to find the regulatory function of microRNA-26 (miRNA-26b) on the cell proliferation and apoptosis of ovarian CSCs. Our studies show that miR-26b is under-regulated in human CD117+CD44+ ovarian CSCs. The miR-26b overexpression inhibits the cell proliferation and promotes cell apoptosis. Moreover, phosphatase and tensin homolog (PTEN) is found to be a functional target of miR-26b. Moreover, PTEN overexpression reversed the effects of miR-26b on the cell proliferation and apoptosis. PTEN overexpression remarkably accelerated the cell proliferation, and inhibited cell apoptosis. These results indicate that miR-26b regulates cell proliferation and apoptosis of CD117+CD44+ ovarian CSCs by targeting PTEN.>
A case of hemolytic anemia associated with interstitial lung disease, arthralgia and fever caused by Mycoplasma pneumoniae
Authors: Micarelli David , Santoboni Gianluca , Tarnani Michela , Angrisani Claudio , Fiorentini Alessandra , Meschini Carlo
Published: February 2021

Pulmonary interstitiopathies have become the most diagnosed forms of pneumonia in 2020 due to the COVID-19 pandemic. The spectrum of interstitiopathies is broad and includes idiopathic diseases and secondary forms. In April 2020, a 36-year-old man admitted to our department for arthralgias, fever, asthenia, cough, and dyspnea. In January 2020 fever, cough, arthralgias and asthenia appeared. In April, his general condition worsened with development of macrohematuria, malaise, and intense asthenia. On admission, the patient presented pale, asthenic and symptomatic for dyspnea and arthralgias. There was objective joint pain in the small joints of the hands, elbow, and knees with morning stiffness and decreased strength. CT of the chest documented ground-glass opacities in both lung fields. He performed 2 swabs for SARS-CoV2, which were negative. On hematochemical examination: IgM 332 mg/dL and ferritin 700.2 ng/ml. At venous blood smear peripheral venous blood, agglutination of erythrocytes. The serology (IgM) for M. Pneumoniae was positive with agglutinins in the serum; Doxaciclina was started. There was a progressive normalization of hemoglobin levels and cold agglutinins were gradually reduced and were no longer detected at 15 days after the start of treatment. At one month after discharge, pulmonary function had fully recovered and the picture of hemolytic anemia was resolved.
Michele Minolli: in ricordo di un Maestro
Authors: Coin Romina
Published: February 2021

In memoria di Michele Minolli, l’A. ripercorre gli aspetti essenziali del modello teorico-clinico che ha elaborato nel corso della sua vita, mettendo in risalto la questioni che hanno animato la sua ricerca e il suo impegno nella formazione.
La fraternità, perché? Resistere alla crudeltà del mondo
Authors: Zito Salvatore , Vanni Fabio
Published: February 2021

Non disponibile.
Emergenza COVID-19: riflessioni sull’esperienza di collaborazione all’iniziativa di aiuto psicologico telematico attuata dal Ministero della Salute
Authors: Bonassi Elena
Published: February 2021

Non disponibile.
Killi Zeminlerin Özelliklerinin Uçucu Kül Kullanarak İyileştirilmesi
Authors: DEHGHANİAN Kaveh
Published: February 2021

Dispersif ve şişen topraklar sorunlu topraklar olarak tanımlanır ve birçok mühendislik yapısında ciddi sorunlara neden olurlar. Son yıllarda, bu toprakların özelliklerini geliştirmek için atık maddeler kimyasal katkı maddesi olarak kullanılmaktadır. Ekonomik sebeplerden dolayı ve kimyasal katkı maddelerinin hızlı uygulanması sayesinde geoteknik mühendisliğinde geniş uygulama alanı kazanmıştır. Uçucu kül, kömürün yanmasıyla oluşan en yaygın atık maddelerden biridir. Bu atık malzemenin kullanılması çevre kirliliğinin önlenmesinde de büyük rol oynamaktadır. Düşük birim ağırlığı, kayma mukavemeti ve düşük çökme hızı gibi uçucu külün özellikleri, bu malzemeyi toprak iyileştirme tekniklerinden biri olarak iyi bir seçenek haline getirir. Ayrıca uçucu kül setler, barajlar ve yollar gibi geoteknik projelerde kullanılabilir. Bu çalışmada killi toprakların mekanik özelliklerini iyileştirmek için uçucu külün etkisi araştırılmıştır. Elit analizi, su içeriğinin belirlenmesi, Atterberg limitleri, Standart Proktor ve üç eksenli kesme testleri İllit kil örneklerinin% 0,% 5,% 10,% 15,% 20 ve% 25 uçucu kül ile karıştırılmasıyla gerçekleştirilmiştir. Bu deneylerin bir sonucu olarak, numunenin plastiklik indeksi ve kohezyonu, uçucu kül içeriğinin artmasıyla azalmıştır. Ek olarak, sadece% 5 kül içeriği eklenerek sürtünme açısı arttırıldı. Karışımdaki uçucu külün daha büyük içeriği için, numunenin sürtünme açısı azalır. Sonuç olarak, optimum yüzde olarak % 5 uçucu kül ve kil karışımı önerilebilir. Elde edilen sonuçlar, killi toprağın uçucu kül kullanılarak etkili bir şekilde stabilize edilebildiğini göstermektedir.
Systematic CMA of the U-slot Patch with FEKO
Authors: Borchardt John
Published: February 2021

Since its introduction 25 years ago, the probe-fed Uslot patch antenna has remained popular. Recently, Characteristic Mode Analysis (CMA) revealed these devices are governed by Coupled Mode Theory (CMT). Although this principle is conceptually simple, achieving this understanding is only possible through a systematic analysis using CMA. This paper uses the Uslot patch to illustrate a general process for analyzing electrically
small antennas using CMA with the software package FEKO.
Mixed-Mode Effect on Motor Common Mode Current
Authors: Karakasli Vefa , Griepentrog Gerd , Wei Junsheng , Drozhzhin Danil
Published: February 2021

This paper presents the mixed-mode effect on motor common mode current (CMC) in an adjustable speed drive (ASD). It is expected that the motor CMC is lower than inverter
output CMC. However, the measurement result of the ASD shows that the AC motor input CMC is higher than the inverter output CMC in a frequency range. By using a mixed-mode (MM) 6-port networks, it is proven that the AC motor input CMC is higher due to an MM CMC which is generated from differential mode current.
A High Gain Lens-Coupled On-Chip Antenna Module for Miniature-Sized Millimeter-Wave Wireless Transceivers
Authors: Moosavifar Milad , Wentzloff David
Published: February 2021

This paper presents high gain and compact Transmit/Receive (TX/RX) integrated antennas in a standard BiCMOS 130nm technology for millimeter-scale millimeter-wave (mm-wave) applications, including high data rate radios and high resolution radars. The proposed TX/RX antenna module utilizes an integrated dipole antenna for the receiver and a slot antenna for the transmitter, placed orthogonally. The achieved gain and radiation efficiency are 5.7dBi and 41.3% for the slot antenna, respectively, and 6dBi and 39% for the dipole antenna. The link budget is improved by 16dB by optimization on the geometry as
well as application of a high resistivity hemispheric silicon dielectric lens.
Percepción de la calidad de vida del adulto mayor en México (Perception of the quality of life of Mexican older adults)
Authors: Villarreal Angeles Mario Alberto , Moncada Jiménez José , Ochoa Martínez Paulina Yesica , Hall López Javier Arturo
Published: February 2021

El objetivo del estudio fue evaluar la percepción de la calidad de vida en personas adultas mayores (AM) de dos centros de atención a esta población. Participaron 100 AM entre 60 a 98 años (M = 70.90 ± 9.19 años) distribuidos en dos grupos: a) Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE, n=50), y b) Ciudad del Anciano (n=50). Para el análisis de los datos se realizó un análisis multivariado de varianza (MANOVA), debido a las 6 dimensiones del instrumento WHOQOL-OLD para la calidad de vida. Dos dimensiones mostraron significancia estadística (p ≤ 0.05), capacidades sensoriales (CS) y participación social (PAIS). En conclusión, los adultos mayores del ISSSTE tuvieron una percepción más alta en el puntaje de la dimensión CS; en contraste con los AM de la Ciudad del Anciano. Al analizar la dimensión de PAIS, sucede lo contrario, los adultos mayores de la Ciudad del Anciano reportaron una percepción más alta que los AM del ISSSTE. 
Abstract.The objective of the study was to assess the perception of the quality of life in older adult persons (OA) from two institutions attending this population. Participants were 100 OA between 60 to 98 years (M = 70.90 ± 9.19 yr.) distributed in two groups: a) Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE, n = 50), y b) Ciudad del Anciano (n = 50). For the analysis of data, a multivariate analysis of variance (MANOVA) was performed, due to the 6 dimensions of the WHOQOL-OLD instrument for the quality of life. Two dimensions showed statistical significance (p ≤ 0.05), sensory abilities (SAB), and social participation (SOP). In conclusion, the biggest adults on the ISSST had a higher perception of the SAB dimension question; in contrast to the AM of Ciudad del Anciano. In analyzing the dimension of SOP, the opposite happens, the larger adults in Ciudad del Anciano reported a higher perception than the AM of the ISSSTE.
Efficacy in positions 1 and 2 in simple temporary numerical inequality at 15th Water polo World Championship (Eficacia desde posiciones 1 y 2 en situación de desigualdad en el 15º Campeonato del Mundo de Waterpolo)
Authors: Sabio Lago Yurema , Argudo-Iturriaga Francisco M. , Guerra-Balic Myriam , Cabedo-Sanromà Josep
Published: February 2021

The aim of this study was twofold: to know if the left-handed players are more effective in the goal categories and getting positive actions, in 1 and 2 position, than the right-handed in the same position at numerical inequality. To ascertain if the shots in 1 and 2 position, are less effective than the rest of the positions in the goal categories. A nomothetic observational, multidimensional and punctual design was used. The sample was the 389 shots and the 182 positive actions of 24 games (12 male and 12 female) at 15th FINA World Championship held in Barcelona. To record the data was used an ad hoc instrument for observation through the Sport Code Version Pro V9. Descriptive and Chi-square test was applied to study the relationship between variables. Left-handed players are more effective than right-handed players are if they are related to the goal and positive action categories in position 1. Shots from position 1 are the second least effective while position 2 is the fifth most effective. 
Resumen. El objetivo de este estudio fue doble: saber si los jugadores zurdos son más efectivos en las categorías de gol y obtener acciones positivas, en la posición 1 y 2, que los diestros en la misma posición en la desigualdad numérica. Determinar si los lanzamientos desde posición 1 y 2 son menos efectivos que desde el resto de posiciones en las categorías de gol. Se utilizó un diseño nomotético observacional, multidimensional y puntual. La muestra fueron los 389 tiros y las 182 acciones positivas de 24 juegos (12 masculinos y 12 femeninos) en el 15º Campeonato Mundial FINA celebrado en Barcelona. Para registrar los datos se utilizó un instrumento ad hoc para observación a través del software Sport Code Version Pro V9. Se aplicó la prueba descriptiva y de Chi-cuadrado para estudiar la relación entre las variables. Los jugadores zurdos son más efectivos que los diestros si están relacionados con el objetivo y las categorías de acción positiva en la posición 1. Los lanzamientos desde la posición 1 son los segundos menos efectivos, mientras que desde la posición 2 es la quinta más efectiva.
Efectividad de un programa educativo en Educación Física para fomentar las habilidades socioafectivas y prevenir la violencia en educación primaria (Effectiveness of educational program in physical education to promote socio-affective skills and prevent
Authors: Aguilar Herrero Maria Dolores , García Fernández Cristina Mª , Gil del Pino Carmen
Published: February 2021

Los programas basados en la mejora de las relaciones interpersonales y el ajuste emocional y social de los escolares han demostrado ser efectivos en la prevención de problemas de naturaleza social como el bullying. Sin embargo, el número de programas para promover las competencias socioemocionales es escaso. La Educación Física constituye una materia clave para el desarrollo de las mismas. Este artículo diseña, examina y evalúa una intervención para promoverlas entre los escolares de Educación Primaria. Para ello, se ha diseñado un estudio longitudinal, ex post facto, pre-post con un grupo experimental. Participaron 75 escolares con edades comprendidas entre 10 y 12 años (M =10.81; DT = 0.33). La intervención incluyó elementos comunicativos, expresivos, creativos y estéticos para promover competencias emocionales y sociales, desde el módulo de Expresión Corporal durante las clases de Educación Física. Los resultados mostraron que la práctica de las habilidades socioafectivas mejora las relaciones personales. Las conclusiones subrayan la necesidad de promover programas que desarrollen la competencia social del alumnado.
Abstract. Programs based on improvement interpersonal relationships and emotional and social adjustment of schoolchildren have been identified as effective strategies in prevention and intervention strategies against social nature problems such as bullying. However, the number of programs to promote these skills is low. Physical Education is a key subject for development of socio-emotional skills in students. This article designs, examines and evaluates an intervention to promote social and emotional skills among primary school children. For this, a longitudinal study, ex post facto, pre-post with the experimental group has been designed. 75 schoolchildren aged between 10 and 12 participated (M = 10.81; SD = 0.33). The intervention included communicative, expressive, creative and aesthetic elements to promote emotional and social competencies, from the Body Expression module during Physical Education classes. The results showed that the practice of socio-affective skills improves personal relationships. The conclusions highlight the need to promote programs that develop students' social competence.
El funcionamiento asambleario como mecanismo de consenso en un proceso de creación grupal (Assembly functioning as consensus mechanisms in the process of group creation)
Authors: Murillo-Pardo Berta , Canales-Lacruz Inma , Lorente-Echeverría Silvia , Corral-Abós Ana
Published: February 2021

Este artículo identifica los factores de la interacción social que facilitan y dificultan el proceso de creación grupal en un proyecto interdisciplinar de acrosport denominado “La voz del rehén”. La muestra estuvo formada por 65 alumnos/as –36 hombres y 29 mujeres– con 21.42±1.69 de media de edad de la mención de educación física del Grado de Magisterio de Educación Primaria de la Facultad de Educación de la Universidad de Zaragoza –España–. Cada grupo de creación diseñó y mostró una propuesta de acrosport, la cual fue elaborada durante el transcurso de tres asignaturas de la mención de educación física –actividades físicas de oposición-colaboración; actividades físicas individuales; y actividades físicas artístico-expresivas–. La recogida de datos fue a través de unos informes grupales que fueron cumplimentados sobre la interacción social desencadenada en el proceso de creación grupal. Posteriormente se realizó el análisis de contenido de dichos informes grupales. Para el tratamiento de los datos se utilizó el NVIVO 11. Los resultados mostraron que: a) el funcionamiento asambleario es el principal mecanismo utilizado para el consenso colectivo; b) la pertenencia y el compromiso grupal favorecen los procesos de creación.
Abstract. This article outlines the factors of social interaction that facilitate and hamper the process of group creation in an interdisciplinary acrosport project based on sustainable development goals called “The hostage voice”. The sample consisted of 65 students –36 men and 29 women– with an average age of 21.42±1.69 from the physical education module of the of Primary Education Bachelor at the Faculty of Education of the University of Zaragoza -Spain-. Each creation group designed and showed an acrosport proposal based on the sustainable development goals, which was elaborated during the course of three subjects of the mentioned module -physical activities of opposition-collaboration; individual physical activities; and artistic-expressive physical activities-. Data regarding the social interaction triggered by the group creation process was collected through reports filled out by each group. Later, the content analysis of these reports was carried out. For the analysis of the data, the software NVIVO 11 was used. The results showed that: a) the assembly discussion is the main mechanism used for collective consensus, b) the group commitment favours the processes of creation.
IMPLEMENTASI METODE FUZZY TSUKAMOTO DALAM MEMPREDIKSI JUMLAH PRODUKSI TMG
Authors: Juliana Eki , Kurniawan Ragil
Published: February 2021

Abstrak: Usaha kuliner adalah salah satu usaha yang banyak digemari dan diminati oleh masyarakat. Sejak dulu hingga sekarang, usaha kuliner seperti jajanan khas daerah terus berkembang tiada habisnya. Salah satu jajanan khas daerah yang berasal dari kota Sampit yaitu Telur Mata Gajah. Di kota Sampit sendiri salah satu usaha kuliner yang Sering di cari warga dan cukup dikenal yaitu Telor Mata Gajah Amrozy yang berlokasi di Jalan Yos Sudarso atau Kompleks Pujasera di Kota Sampit, persis bersebelahan dengan Taman Kota Sampit. Menjadi tempat jajanan yang dikenal dan ramai dikunjungi membuat pemilik usaha kesulitan dalam menentukan jumlah produksi yang mesti disiapkan dalam memenuhi jumlah permintaan dalam penjualan nya. Penelitian ini bertujuan untuk menyelesaikan permasalahan di atas dengan menggunakan sebuah metode. metode yang digunakan oleh penulis pada penelitian ini adalah metode fuzzy Tsukamoto. Dari hasil penelitian yang dilakukan oleh penulis diperoleh hasil yakni 2162 TMG yang harus diproduksi. Sehingga hasil penelitian ini bisa menjadi pertimbangan untuk menentukan  jumlah rata rata dalam memproduksi TMGKata kunci: Produksi, Prediksi Produksi, Fuzzy Tuskamoto, Telur Mata GajahAbstract: The culinary business is one of the most popular companies and is in demand by the community. Since then until now, culinary companies such as local specialties have continued to grow endlessly. One of the typical regional snacks from the city of Sampit is Elephant Eye Eggs. In the town of Sampit itself, one of the culinary businesses that are often sought after by residents and are quite well known is Telor Mata Gajah Amrozy, which is located on Jalan Yos Sudarso or the Pujasera Complex in Sampit City, right next to Sampit City Park. Being a well-known and visited place for snacks makes it difficult for business owners to determine the production required to meet the demand for sales. This study aims to solve the above problems by using a method. The method used by the author in this study is the Tsukamoto fuzzy method. From the author's research results, it was found that 2162 TMG had to be produced. So that the results of this study can be a consideration to determine the average amount in creating TMGKeywords: Production, Production Prediction, Fuzzy Tsukamoto, Elephant Eye Eggs
MEDIA PROMOSI DAN PENJUALAN IKAN TUNA LOIN PADA PT. UD RAUL BERBASIS WEB (Studi Kasus : PT. UD RAUL )
Authors: Djafar Rusman , Noh Junaidi , Ibrahim Adelina
Published: February 2021

Abstrak: PT. UD RAUL merupakan perusahaan yang bergerak dalam penjualan ikan tuna loin, Namun dalam pelayanan penjualan PT. UD RAUL seperti pemesanan ikan dan transaksi pembayarann masih bersifat manual dimana pembelian melakukan transaksi pembelian ikan secara langsung PT. UD RAUL yang menjadi salah satu permasalahannya. Dalam hal ini guna mempermudah pelanggan untuk mendapatkan pelayanan tersebut, berdasarkan masalah diatas maka perlu adanya suatu aplikasi Media Promosi Dan Penjualan Ikan Tuna Loin Pada PT. UD RAUL Berbasis Web. Penelitian ini menggunakan Metode Prototype sebagai Metode Pengembangan dan pemodelan Aplikasi menggunakan bahasa pemrograman Java pada bagian web dan bahasa pemrograman PHP Pada bagian Administrator dengan MySQL untuk pengolahan databasenya. Sistem Informasi Penjualan Ikan Tuna Loin Pada PT. UD RAUL Berbasis Web Dapat mengumpulkan, mengidentifikasi, menyimpan, mengolah dan memberikan informasi Penjualan Pada PT. UD RAUL yang menjadi target dalam penelitian ini.Kata Kunci: Website, Promosi, Penjualan, Tuna LoinAbstract: PT. UD RAUL is a company engaged in the sale of tuna loin, however in sales services PT. UD RAUL, such as fish orders and payment transactions, is still manual, where purchases make fish purchases directly. PT. UD RAUL, which is one of the problems. In this case, to make it easier for customers to get these services, based on the above issues, it is necessary to apply for Media Promotion and Sales of Tuna Loin at PT. Web-based bolted application supported Web application for database manager by admin. This research uses the Prototype Method as a method of application development and modeling using the Java programming language on the web and the PHP programming language on the Administrator section with MySQL for database processing. Information System for Tuna Loin Sales at PT. Web-Based UD RAUL Can collect, identify, store, process and provide sales information at PT. UD RAUL, which was the target of this researchKeywords: Website, Promotion, Tuna, Sales
NR 17 NO CONTEXTO ACADÊMICO: APLICADA NA EDUCAÇÃO TÉCNICA
Authors: Maziero Rômulo , Fortunato Frederico da Silva
Published: February 2021

A natureza interdisciplinar da ergonomia a torna notavelmente aplicável a vários campos que envolvem desempenho humano. A educação é um campo em que a ergonomia pode dar uma contribuição significativa, mas a aplicação da ergonomia educacional recebe apenas uma atenção limitada. Deste modo, o objetivo do presente estudo foi analisar os riscos ergonômicos, de servidores estaduais (professores, administrativo) e terceirizados (auxiliar de serviços gerais, vigilantes) de uma instituição de educação profissional técnica de nível médio, de forma a contribuir com a organização e/ou reorganização ergonômica no ambiente educacional. Foram conduzidos questionários eletrônicos semiestruturados quantitativos em forma de entrevistas individuais, para os grupos servidores e terceirizados. Posteriormente, a intervenção no ambiente educacional envolveu um curso com a temática ergonomia educacional, aplicado ao grupo alunos, além de uma campanha educativa - Webinar. Os resultados evidenciaram, de forma geral, os níveis de desconforto/dor classificados em moderado e intenso, com base nos questionários respondidos pelos servidores e terceirizados. Notou-se ainda o desconhecimento dos alunos em relação à ergonomia educacional e áreas afins. Conclui-se que é necessária intervenção educacional, ergonômica e interação professor-aluno-ambiente na temática ergonomia.
AN EVALUATION OF THE FACTORS INFLUENCING VEGETABLE COMMERCIALIZATION IN KENYA
Authors: M’ithibutu Mbiti Job , Gogo Elisha Otieno , Mangale Fikirini Lugogo , Baker Gregory
Published: February 2021

Purpose: The purpose of the study was to establish factors that influence vegetable commercialization among smallholder farmers of fresh vegetables in Kenya. The present study defined commercialization against farmer characteristics including portion of land committed to vegetable farming, share of household income generated from it, and the producers’ perception that the vegetables they consumed at the farm were produced or procured without any substantial cost.

Methodology: The researcher adopted a cross-sectional survey design to randomly recruit a sample of crop farmers (n=118) from Kirinyaga and Kiambu counties in Kenya. Data on agrochemical use, crop diversity and scale as well as logistical issues regarding proximity to markets and social status of the crop farmers were collected using a researcher-administered questionnaire in a one-on-one interview. These data were initially entered on MS Excel spread sheets for cleaning and later transferred to Minitab (Ver 12) for statistical analyses. Principal component analysis (PCA) was used to isolate crucial commercialization factors responsible for varying agrochemical use behaviours among crop farmers and later presented in scree plots.

Results/Findings: The study revealed that commercialization of tomatoes and kale was real in different areas of study which was influenced by structural and socio-demographic factors. From the study findings, structural policies to promote horticulture and high value crop production had a positive impact on production of vegetables while wildlife conservation and livestock development resulted to human-wildlife conflicts due to agrochemical abuse. Various socio-demographic factors that influence commercialization of vegetables included: household size, farm size, proportion of land used for vegetable production and household income. It emerged that household size (Eigen value EV=3.63), income (EV=2.61) and farm size (EV=1.27) accounted for 68.4% of variability in agrochemical abuse. This finding also explains their marginalization from county government extension services and high costs of market access.

Unique contribution to theories, practice and policy: The study finds that vegetable farmers’ perception of commercialization leaned more towards increasing production in response to consumer demand and not necessarily to raise household food supplies. Famers dedicated over two thirds (66.67%) of their land to vegetable farming to support their livelihood (97.1%, SE= 1.30). Commercialization of vegetable farming was influenced by the level of education (SE=3.68). The study found out that that access to ICT equipment, particularly mobile phones, were the prime means via which farming techniques and agribusiness practices were learnt or improved (V= 0.196 Pearson, p=0.11).
Overview of Forensic DNA Profiling and Database
Authors: Sabreen Aboujildah Sabreen
Published: February 2021

Deoxyribonucleic acid (DNA) profiling, has had a tremendous impact on forensic genetics. Before DNA profiling, all forensic genetic casework (e.g., Paternity testing, criminal casework, individual identification) was performed using classical serological genetic markers. Blood groups, human leukocyte antigen (HLA), and polymorphic protein and enzymes were used for solving forensic genetic casework using immunological and electrophoretic methodologies. These genetic markers were nevertheless limited when it was necessary to analyze minimal or degraded material, which is commonly involved in forensic cases. An STR is a region of human DNA containing an array of tandem repeats. Arrays range from only a 10 to about a hundred repeated units. This essay confers the basic concepts of operating of DNA in the criminal investigation. This review primarily summarizes the major tandem repeat markers used in forensic DNA profiling, that assist criminal’s conviction, exonerate the inferring individuals, and recognize victims of violence, catastrophes, and armed conflict.
Inclusive training as a leading direction modern policy of education
Authors:   South Kazakhstan State Pedagogical University, Masaliyeva Zhanar
Published: February 2021

The article discusses the realization of the idea of "introducing" children with special educational needs into the educational process within the framework of integration of special education and the state of inclusive education in our Republic, including in the South Kazakhstan region in accordance with international human rights documents declaring equal rights for children on education. The implementation of the idea "introduction" in the educational process justifies the need for socialization of children with special educational needs, based on the requirements of society, regulatory documents and scientific and methodological guidelines, the region's readiness for inclusive education, migration processes and demographic, ethnotic characteristics and specific conditions and indicators in the system of preschool, primary and secondary education.
DISTANCE LEARNING OPPORTUNITIES IN THE COVID-19 PANDEMIC
Authors:   South Kazakhstan State Pedagogical University, Meiirbek Nursaule
Published: February 2021

Distance learning is often associated with part-time learning, but it means a completely different concept. Distance learning - traditional and specific methods, tools and forms of learning based on computer and telecommunication technologies in the educational process, can be full-time or part-time. At the Distance Learning Center, the student's own research is conducted according to a developed program. Online education allows students to fully integrate into the learning environment - listening to lectures, completing assignments, consulting with teachers and talking to students through the Internet.
Development of lexical skillsin children with speech disorders and their principles
Authors:   South Kazakhstan State Pedagogical University, Turmakhanova S , Tanabayeva G
Published: February 2021

The article discusses the theoretical foundations and ways of developing lexical skills and abilities of children with speech disorders. We considered effective methods for developing speech skills in children with disabilities. Defining learning methods by source of knowledge we studied the close relationship with their grouping by type of knowledge. In order to enrich the vocabulary of children with speech disorders, each teacher should pay special attention to the following processes of speech development in Kazakh language lessons. These are: the ability to correctly use a word in its meaning; the ability to correctly give a written game; the ability to use keywords. Depending on the features of language proficiency, the ability to use language tools for communication purposes, to improve the level of skills and abilities of language development, are considered on the basis of known language systems, language structures and language units, educational materials at school.
علاقة الزمان بالحدث في القصيدة الجاهليّة
Authors: الحاج حسن رائد رشيد
Published: February 2021

يشكِّل الزمان عنصراً مهماً من العناصر القصصية في القصيدة الجاهليّة، إلى جانب المكان والشخصيات والحدث والحوار والصراع، ويسعى هذا البحث إلى دراسة علاقة الزمان بالحدث من خلال تحديد الزمن في القصّة الشعريّة، وإظهار تأثيره في الحدث القصصي في نماذج شعريَّة مختلفةٍ لشعراء مشهورين من أمثال امرئ القيس والنابغة الذبياني والأعشى وغيرهم، وكذلك من المُقلّين مثل قيس بن الحداديّة.
ويسعى البحث إلى توضيح تقنية السرد الاسترجاعي الذي يعني أي حدثٍ أو مشهدٍ سابقٍ على الزمن الذي يصفه العمل الأدبي، كما يهدف إلى إبراز دور تقنية الحذف في تسريع السرد القصصي، فهو يحيل على مدَّةٍ زمنيَّةٍ لا يوافقها حيِّزٌ في النصّ الأدبيّ، فيتخطى الشاعر من خلالها الأحداث غير المهمة بالنسبة إلى القصّة الدراميّة.
الكلمات المفتاحيّة: القصيدة الجاهليّة، العناصر القصصيّة، السرد الاسترجاعي، الحدث القصصيّ، الحذف، القصّة الدراميّة.

The study investigated the connections between the time settings and the historical events that occurred during those periods. In any dramatic work, it is known that the time element is dependent upon the internal perspective of the characters. One technique of temporal narration focused upon the usage of an analepsis or flashback, which changes the time perspective of a character and presents a story within a story. The study also attempts the influence of such technique on the narrative structure as exemplified in three different poetic models: Imru 'al-Qais, al-Nabigha al-Dhibiyyi, al-Asha and others.

Another technique (ellipses) utilizes was placing time gaps in the narrative to increase the pace of the events of the story to eliminate less important events. This was a commonly used technique to move a story along and maintain interest. When narrative descriptions are drawn out too long, the flow of the story slows down and loses momentum.
Keywords: Pre-Islamic (Jahily) Poem, Narration Elements , analepsis, narrative events, ellipses, dramatic story.
قاعدة: الحقيقة تترك بدلالة العادة
Authors: العجمي مبارك سعود
Published: February 2021

سلطت الضوء في هذه الدراسة على قاعدة فقهية عظيمة لها أهميتها في علم القواعد الفقهية، وهي قاعدة الحقيقة تترك بدلالة العادة، وقد اتبعت في دراستي لهذه القاعدة منهج استقرائيا ووصفيا تحليليا، وقسمت الدراسة إلى مطالب سبعة، تناولت في المطلب الأول المعنى الإجمالي لقاعدة الحقيقة تترك بدلالة العادة، وذكرت في المطلب الثاني ألفاظ القاعدة، وبينت في المطلب الثالث أدلة القاعدة، وفي المطلب الرابع تناولت القواعد ذات الصلة بالقاعدة، وفي المطلب الخامس تناولت بعض الفروع الفقهية للقاعدة، وفي المطلب السادس قمت بإيراد تطبيقات فقهية على القاعدة، وفي المطلب السابع قمت بإيراد تطبيقات معاصرة للقاعدة، وفي المطلب الثامن تناولت مستثنيات القاعدة، ثم ختمتُ الدراسة بخاتمة اشتملت على أهم النتائج والتوصيات. وتوصلت الدراسة إلى أن الحقيقة أنواع أربعة: لغوية، وشرعية، وعرفية عامة، وعرفية خاصة، وأن المقصود بالعادة هو الاستمرار على شيء مقبول للطبع السليم، والمعاودة إليه مرة بعد أخرى، وهي المرادة بالعرف، وأن قاعدة الحقيقة تترك بدلالة العادة تندرج تحت قاعدة كبرى هي: العادة محكمة.
الكلمات المفتاحيّة: الحقيقة، تترك، دلالة العادة.

I highlighted in this study a great jurisprudence base of importance in the science of jurisprudence, a rule of truth left in terms of habit, I have followed in my study of this rule inductive method and descriptive analytical, The study was divided into seven demands, which dealt in the first request with the overall meaning of the rule of truth left as a function of habit. In the sixth requirement, I mentioned doctrinal applications on the rule. I then concluded the study with a conclusion containing the most important findings and recommendations. The study found that the truth has four types: linguistic, legitimacy, customary public, and customary, and that the custom is usually to continue something acceptable to the proper printing, and return to it again and again, which is the desire to custom, and that the rule of truth left in terms of habit falls under the rule is Custom Court.
Keywords: truth, leave, significance of habit.
Opportunities for the development of cross-border tourism in South-East Europe: The case of Kosovo-Albania border.
Authors:   University of Prishtina, Kosovo, RAMADANI Ibrahim , DIBRANI Etnike , HOTI Dardan , GASHI Ferim ,   University of Prishtina, Kosovo
Published: February 2021

This paper examines the regional and institutional opportunities for cross-border cooperation, networking and tourism development at the Kosovo- Albania border, which is one of the internal borders of the Albanian ethnic territory. Completion of the study confirms the hypothesis that closure of states within the classical boundaries causes obstacles, not only for the development of cross-border tourism, especially when viewed from the perspective of sustainable tourism development in this region. While, on the other hand, cross border cooperation enables exchanges of experiences, Ideas between communities, etc., and all this reflects on the economic prosperity of these areas. In the process of developing the countries of southern Europe, particular importance has been paid to settlements and infrastructure away from border areas, while border regions have remained underdeveloped and without prospects. Development has been challenged in many border areas, including all Balkan states, while these areas were abolished as a result of the population's departure. The idea in this case study, aims to "create" the unique tourist zone "Green Albania" between the two countries, with its unique natural characteristics, leading to economic, cultural and national integration, as well as preservation and advancing the natural and cultural values of the cross-border territory.
Using synthetic data for the dissemination of computational geospatial models
Authors:   University College London, Centre for Advanced Spatial Analysis, London, UK, CHELIOTIS Kostas
Published: February 2021

Detailed datasets of real-world systems are becoming more and more available, accompanied by a similar increased use in research. However, datasets are often provided to researchers with restrictions regarding their publication. This poses a major limitation for the dissemination of computational tools, whose comprehension often requires the availability of the detailed dataset around which the tool was built. This paper discusses the potential of synthetic datasets for circumventing such limitations, as it is often the data content itself that is proprietary, rather than the dataset schema. Therefore, new data can be generated that conform to the schema, and may then be distributed freely alongside the relevant models, allowing other researchers to explore tools in action to their full extent. This paper presents the process of creating synthetic geospatial data within the scope of a research project which relied on real-world data, originally captured through close collaboration with industry partners.
InunIB: Analysis of a flood database for the Balearic Islands
Authors:   Universitat de les Illes Balears, Departament de Geografia, Palma de Mallorca, Spain, GRIMALT Miquel , ROSSELLÓ Joan ,   Universitat de les Illes Balears, Departament de Geografia, Palma de Mallorca, Spain
Published: February 2021

This paper presents a database that includes all the known flood events in the Balearic Islands from the 15th century to 2018. The research uses historical sources, such as chronicles, church records and public archives, while for recent events, the data is obtained from newspapers information and official reports from local and regional authorities. The result is that more than 200 floods have been identified. The next step is study the obtained data. In that sense, the temporal distribution is analysed. Some other characteristics, such as the evolution of damaged areas or the increase of events during the 20th century, are presented. The database structure allows to be updated after recent events and the data presented can be considered as a first step to gain a valuable knowledge of the flooding risk in the Balearic Islands and can contribute to provide information on future events in terms of spatial and temporal flood impact.
La licenciatura en Turismo Alternativo de la Universidad Intercultural Maya de Quintana Roo (UIMQROO), desde la mirada intercultural de los egresados
Authors: Medina Martín Cecilia del Socorro , Navarro Favela Margarita de Abril , Uc Angulo Andrea Danilu
Published: February 2021

Para evaluar la pertinencia de la licenciatura en Turismo Alternativo de la Universidad Intercultural Maya de Quintana Roo (UIMQROO), en marzo de 2018 las profesoras de este programa educativo trabajamos con egresados mediante la metodología sociocrítica1 y analizamos sus percepciones, expresadas tanto en un cuestionario individual como en un grupo focal. En ambos casos, se plantean cambios que responden a las competencias requeridas en las demandas laborales del turismo alternativo, a la vez que reconocen, por tener una mirada intercultural, la importancia de seguir incorporando los saberes tradicionales y de fortalecer la identidad con base en la lengua y la cultura maya. Asimismo, los egresados señalan la relevancia del respeto a la diversidad, lo cual revaloriza la pertinencia y el aporte social del modelo intercultural con énfasis en la vinculación comunitaria. 

 

1 El método sociocrítico se caracteriza por hacer partícipes a los involucrados en el empoderamiento social, es decir, el investigador sólo es un facilitador e implica la adopción de decisiones consensuadas para la transformación desde el interior. Todas estas características son tomadas del paradigma estudiado por Philipp (1998). También implica el empleo de herramientas participativas para transformar la realidad social y el intercambio de conocimiento como apropiación social.
Erosion-Corrosion of AISI 302 Stainless Steel Sudden Expansion Pipes in High Salt Wastewater: Effect of Fluid Flow on Different Positions of a Sudden Expansion Pipe
Authors: Wang Weibing , Ren Yongsheng
Published: February 2021

Erosion-corrosion (E-C) is common in chemical industries. Sudden expansion pipes (SEP) are one of the flow components which may experience severe erosion rates. Computational fluid dynamic modeling (CFD) and flow-through experiments were used to study E-C for a SEP of AISI 302 stainless steel. A typical geometry for SEP was investigated: 20 mm diameter inlet pipe, 40 mm diameter outlet pipe, with an inlet flow rate of 0.1 m/s, and 10 wt% concentration of SiO2. CFD simulation results showed that turbulence energy and wall shear were highest at 5 mm and fluid axial velocity was lowest at 5 mm from the inlet/outlet SEP connection point. E-C test results showed that the most severe E-C occurred between 5 mm and 7 mm downstream of the SEP. At deeper lengths into SEP, the corrosion rate decreased and remained constant. The results indicated that increasing wall shear and turbulence energy increased the mechanical effects of particles on SEP and hence increased the E-C rates of the reattachment point. This work provides a means of understanding E-C behavior and predicting erosion damage of SEP.
Lack of Change Information and End User Grumbling: Mediating Role of Fear of Unknown and Moderating Role of Emotional Regulation
Authors: Bangash Rida , Khawaja Kausar Fiaz , Chughtai Sumayya
Published: February 2021

User resistance is a complex phenomenon and is considered a major constraint towards the successful implementation and usage of information technology. Hence, in order to investigate the factors that may lead to user resistance; the current study proposes and investigates the mediating role of fear of unknown between lack of change information and end-user grumbling, and the moderating role of emotional regulation between the relationship. Emotional self-regulation theory has been used as an overarching theory that explains the research model proposed and tested in the study. Using a Quantitative approach, the survey was conducted and data was collected from 334 users of FBR systems. With the help of SPSS and MACRO PROCESS, statistical tests were conducted and links were tested. Results revealed that all hypotheses were accepted. Along with these discussions, research implications and recommendations are also provided.
Phenotypic tests and Molecular detection of blaOXA-48 and blaNDM-1 genes among carbapenem-resistant Enterobacteriaceae isolated from allograft liver recipients
Authors: M. Awad Samah , M. Ghoneim Enas , M. Abd El Aziz Azza , A. El Shaaraway Yasmin , Taha Mohammad
Published: February 2021

Background: Infections with carbapenem resistant Enterobacteriaceae (CRE) cause
significant morbidity and mortality in Liver transplant recipients. Accurate detection of
CRE is the first step in combating this problem. Objectives: to study the distribution of
pathogens and CRE causing infections in liver allograft recipients with special reference
to the impact of pre-operative intestinal colonization with CRE on post-operative
infections, and to investigate the phenotypic tests and to detect the frequency of blaOXA48 and blaNDM-1 genes by duplex PCR. Methodology: A total of 23 CRE isolates were
investigated for carbapenemase production by phenotypic methods such as the modified
Hodge test (MHT), douple disc synergy test (DDST), E test and Rabidec Carba NP
(RCNP) test. Production of blaOXA 48 and blaNDM-1genes was investigated by duplex
PCR. Results: Frequency of CRE that harbored blaOXA-48 and blaNDM-1 genes, as
obtained by PCR, was 47.8% for blaOXA-48, 20.1% for blaNDM-1 and 8.7% of CRE
isolates co-produced the two genes. RCNP test exhibited Sensitivity of 90.9% and 100%
versus 81.1% and 66.6% sensitivities by MHT in detecting blaOXA-48 and blaNDM1genes respectively. E-test had a much higher sensitivity in identifying NDM-1
carpabenemase compared to DDST (100% versus 66.6% respectively).Conclusion:
RCNP test can be done instead of MHT in detecting CRE, as it is more accurate, rapid
and having excellent sensitivity in detecting blaNDM-1 and blaOXA-48 producing
isolates. E-test is more reliable than DDST and can be a valid alternative to PCR in
detecting MBL especially NDM-1 type.
Rate of Carriage of Streptococcus agalactiae among Pregnant Women and Role of Some Virulence Genes
Authors: F. Makled Amal , B. Mahmoud Ahmed , A. Saleh Said , G. Hegazy Sara , G. Mostafa Rasha
Published: February 2021

Background: Although, GBS is a natural flora of the ano-rectal region, it may colonize
vagina and many infants can be infected during the passage through the birth canal. It
has emerged as a leading cause of neonatal infections and deaths. Objectives: To
estimate the rate of recto-vaginal carriage of GBS among pregnant females, describe its
antimicrobial susceptibility profile and to detect some of its virulence genes by multiplex
PCR. Methodology: Vaginal, anorectal and neonatal throat swabs which were collected
from two-hundred and fifty pregnant women were inoculated in Todd-Hewitt broth for
24 hours then inoculated on blood agar plates. Antimicrobial susceptibility testing for
GBS isolates was done and its virulence genes (scpB, bca, rib and HvgA) were identified
by PCR. Also, the relation between these virulence genes and antimicrobial susceptibility
was studied. Results: Among 250 pregnant females, 36(14.4%) were identified as GBS
carriers with exclusive vaginal and anorectal colonization rates of 4% and 10.4%
respectively. All isolates were susceptible to penicillin, ampicillin, cefepime, cefotaxime,
ceftriaxone, vancomycin and linezolid. On the other hand, 19.4%, 80.6%, 44.4% and
13.9% of GBS isolates were resistant to each of erythromycin and azithromycin,
tetracycline, levofloxacin and clindamycin respectively. ScpB, rib, and Hvg-A genes
were identified in 100%, 69.4% and 33.3% of GBS isolates respectively. None of them
had the bca gene. Conclusion: Screening for GBS colonization of pregnant females is
recommended and determination of virulence and different surface proteins would be
relevant for better diagnosis and further possible formulation of a vaccine