bluuebunny/crossref_metadata_2025 huggingface dataset:
Espanhol como segunda língua
Authors: Machado Priscila Costa , Matzenauer Carmen Lúcia Barreto
Published: February 2023

O foco deste estudo piloto foi verificar se brasileiros aprendizes de espanhol como segunda língua (L2) são capazes de perceber a diferença na entoação de interrogativas totais e parciais na língua espanhola, além de examinar se o tempo de aquisição/exposição à língua alvo pode influenciar nesta percepção. Os enunciados interrogativos totais e parciais, na língua espanhola, apresentam como principal propriedade prosódica o movimento na inflexão final, sendo majoritariamente ascendente nas interrogativas totais e descendente nas interrogativas parciais. O corpus foi obtido pela aplicação de cinco testes de percepção a três participantes, estudantes do curso de Letras – Português/Espanhol, sendo dois estudantes do sétimo semestre e um do terceiro. Os resultados mostraram que os participantes apresentaram maior êxito na discriminação da entoação de interrogativas parciais em relação às interrogativas totais, o que se atribui à influência da L1 no processo de aquisição da L2, já que nas interrogativas parciais o padrão entoacional se aproxima nas duas línguas. Quanto ao tempo de exposição à língua alvo, verificou-se que a estudante do terceiro semestre apresenta um processamento mais lento frente aos estímulos da L2. Em trabalhos futuros, irá ampliar-se o número de participantes com diferentes níveis de aquisição da língua espanhola, a fim de observar-se com maior acurácia se, de fato, o tempo de processamento linguístico é maior por estudantes dos semestres iniciais e se, de fato, o nível de compreensão influencia na percepção de aspectos prosódicos da língua espanhola como L2.
Hacia la determinación de la calidad de los ensayos argumentativos a partir del análisis léxico-gramatical de sus introducciones
Authors: Venegas René , Castro-Cano Eleine , Carrasco-Del Carpio Pablo , Choque-Vilca Erika
Published: February 2023

Un género evaluativo escrito que presenta dificultades para los estudiantes universitarios es el ensayo argumentativo (EA). El objetivo de este artículo es relacionar la calidad de las introducciones con la calidad de los EA, considerando sus rasgos léxico-gramaticales. Para el logro de este, seleccionamos 96 EA, producidos en dos fases durante un semestre académico. Luego comparamos, para ambas fases, la evaluación de los EA y de sus introducciones (IEA), así como las características léxico-gramaticales de estas. Posteriormente, correlacionamos los datos de los EA con sus IEA. Finalmente, realizamos un análisis de agrupamiento, según patrones léxico-gramaticales. Los hallazgos indican: a) diferencias significativas entre los EA como entre las IEA de ambas fases, b) patrones léxico-gramaticales distintivos entre ambas fases, c) una correlación alta entre la calidad de los EA y la de las IEA y d) un continuun de calidad entre introducciones. Entre las fases, observamos una mejoría en la calidad de las IEA no solo desde el punto de vista argumentativo, sino que también acorde con el género discursivo. Además, se comprueba la importancia de esta macromovida como predictora de la calidad del contenido. Estos resultados son útiles para la detección temprana de dificultades en la escritura académica.
pluricronotopia da escrita acadêmica na pós-graduação
Authors: Brambila Guilherme
Published: February 2023

Este artigo tem o objetivo de analisar a presença de múltiplos cronotopos manifestados no depoimento de alunas de pós-graduação a respeito do processo da escrita de suas dissertações e tese. Com base na teoria bakhtiniana e guiado pela análise metalinguística (BAKHTIN, [1975] 2002; [1924] 2011; VOLOCHÍNOV, [1929] 2017), o trabalho evidencia três cronotopos que constituem e transformam a experiência de se escrever na pós-graduação. Esses apontamentos propõem a perspectiva de que há diversos fatores que colidem com essa atividade linguístico-discursiva, devendo-se tornar pauta conjunta à formação de novos pesquisadores.
cidade e a natureza em Paisagem matinal de Cida Pedrosa
Authors: Rigamonte Fhilipe Germano , Ramos Wellington Furtado
Published: February 2023

O artigo propõe uma leitura do poema Paisagem matinal de Cida Pedrosa evidenciando os jogos de sentido presentes na paisagem urbana os quais revelam a relação entre a cidade e o sujeito e a presença silenciosa da natureza nesse espaço tão hostil. Para tanto, considera-se algumas noções que contemplem a paisagem enquanto jogo de visível e invisível (BESSE, 2006; DIDI-HUBERMAN, 1998; MERLEAUPONTY, 2003) e a relação da cidade com o campo (WILLIAMS, 1990). Indo um pouco além do caminho dos estudos da lírica brasileira, o trabalho se justifica na possibilidade de se enxergar a natureza não como uma dicotomia do espaço urbano, mas também, como uma importante presença participativa na construção dos sentidos aqui ali circulam. Portanto, em meio ao ritmo acelerado da urbe, elementos naturais se confundem e são raramente, ou nunca, notados como como corpos marcados pela opressão daquele espaço moderno.
Regulação normativa do uso das formas de tratamento do português
Authors: De Moraes Milena Borges , Alves Heloísa Schmitt
Published: February 2023

As instâncias de regulação tentam controlar os usos linguísticos e os sentidos sobre a língua, a partir de uma variedade linguística idealizada, associada à assimetria de poder indicada pela forma usada por um determinado grupo, correspondendo a um conjunto de regras que definem as relações entre os membros da sociedade. Assim, objetiva-se realizar uma leitura diacrônica e discursiva de instrumentos normativos que versam sobre a regulação do uso das formas de tratamento do português, dos séculos XVI, XVIII e XXI, em Portugal e no Brasil. Para a análise dos materiais, mobilizou-se a teoria e os métodos da diacronia, bem como os princípios e os procedimentos da Análise do Discurso de linha francesa, proposta por Michel Pêcheux, na França, na década de 60, e divulgada e ampliada, no Brasil, por Eni Orlandi. Como resultado, observamos que o fio que permeia os discursos produzidos a partir dos instrumentos normativos analisados preserva os pressupostos da tradição europeia no uso das formas de tratamento; contudo, aprimora-se com novos dizeres acerca de uma igualdade idealizada que será, supostamente, alcançada por meio de umas e não outras formas de tratamento.
“No artigo da morte”
Authors: Da Silva David Lopes
Published: February 2023

O ensaio intenta, na encruzilhada de vida e obra do escritor Guimarães Rosa, sugerir que os três dias que decorreram entre a posse na Academia Brasileira de Letras, numa quinta-feira, com a leitura pública do discurso “O verbo & o logos”, e o falecimento do autor, no domingo, estão alegorizados na decisão do personagem da estória “A terceira margem do rio” de “se permanecer (demeurer) naqueles espaços do rio”. Rosa, inúmeras vezes, segundo depoimentos de conhecidos seus, afirmara que tomar posse na Academia poderia matá-lo. Mesmo assim, mesmo tendo demorado (demeuré) quatro anos para se resolver, enfrentou a cerimônia. Como metodologia, o texto rosiano será lido ao lado dos de outros autores, como Blanchot e Derrida. A conclusão do artigo é que, assim como o pai do conto tomou em suas mãos o seu destino e “nunca falou mais palavra”, Rosa decidiu também calar-se para sempre ao finalmente tomar posse da Cadeira n. 2 da ABL.
crítica machadiana e o realismo de uma outra realidade
Authors: Silva Teresinha Vânia Zimbrão
Published: February 2023

O presente trabalho procura mostrar o quanto a crítica machadiana, representada sobretudo pelos nomes de Roberto Schwarz e, em certa medida, do brasilianista John Gledson, questionou os padrões normativos e eurocêntricos da crítica literária ocidental, apresentando uma proposta produtiva para o estudo da obra do escritor brasileiro Joaquim Maria Machado de Assis (1839–1908). O trabalho explicita que a proposta dessa crítica consistiu em ler o texto machadiano como a manifestação do realismo de uma outra realidade. Por fim, conclui que essa crítica não hesitou em desafiar os limites impostos pela Europa ao conceito de realismo literário de modo que este, redefinido, pudesse acolher um excêntrico (fora do centro) realismo brasileiro.
Fios de esperança
Authors: Filho Valdelino Gonçalves Dos Santos , Apolinario Danielle da Silva , Soares Júlia Silveira
Published: February 2023

O presente artigo pretende identificar as marcas da ancestralidade como fio condutor da esperança na trajetória de mulheres negras, personagens de quatro contos do livro Olhos d’água, da escritora brasileira Conceição Evaristo. A pesquisa sobre o tema proposto assume um caráter qualitativo, de cunho exploratório, cuja coleta de dados possui foco na pesquisa bibliográfica. O aporte teórico orientador se baseia nos estudos produzidos sobre sociedades africanas de Amadou Hampâté Bâ (2010), Fábio Leite (1997) e Cunha Júnior (2010). Os resultados apontam para a presença da esperança como elemento constituidor do ser humano numa busca pelo equilíbrio da vida. As lutas dessas mulheres não se findam nelas mesmas, é necessário mais para prosseguir no mundo em busca da harmonia.
Violência e horror
Authors: Trevisan Ana Lucia
Published: February 2023

O artigo estuda o romance Enterre seus mortos (2018), da escritora brasileira Ana Paula Maia, a fim de compreender sua forma singular de instrumentalização da temática da violência, que se configura por meio do efeito de estranhamento, do horror e da expressão do reverso e do oculto na referencialidade. As relações tensivas entre os elementos externos, pertencentes aos contextos sócio-históricos, e os internos, imanentes a estrutura da obra (Candido, 1973; Angenot, 2015), compõem a potência da narrativa na medida em que as construções imagéticas da violência distorcem a imediatez da realidade, revelando um horror hiperbólico que exagera o real até o limite da repulsa e do asco. Ao examinar a estrutura narrativa do romance explicita-se a dramaticidade dos movimentos paradoxais que orientam o tempo presente e observa-se a composição de metáforas reveladoras de certa subjetividade contemporânea.
Silêncios que ecoam
Authors: Esteves Natacha dos Santos , Coqueiro Wilma dos Santos
Published: February 2023

Ambientado na pacata cidade de Cruzeiro, o romance A ponta do silêncio (2016), da escritora gaúcha Valesca de Assis, traz como trama o assassinato de Rudy Treibel, um sujeito pertencente à nata da sociedade cruzeirense e conhecido por todos. A única suspeita do crime é sua esposa, a professora Marga Treibel, que, para se defender, só pode utilizar a escrita, visto que perdeu a voz após o acontecido. Dessa forma, Marga passa a escrever cartas e, por meio delas, mostra detalhes de seu casamento abusivo e do comportamento violento do marido. Com base nisso, o presente estudo se ocupa de escrutinar a dominação masculina perpetrada na vida de Marga, mostrando como isso impactou diretamente no desfecho da obra. Além disso, tendo em vista que se trata de uma personagem escritora, que se expressa pela escrita, o foco analítico deste ensaio também recai sobre o processo de subjetivação que Marga encontra ao escrever, tendo como embasamento estudos oriundos da crítica feminista contemporânea. Ademais, visando à defesa de Marga, estudos sobre a dominação masculina também serão utilizados para ratificar os argumentos da personagem. Palavras-chave: Valesca de Assis; a ponta do silêncio; dominação masculina; violência doméstica.
On a production-inventory system with defective items and lost sales
Authors: R. Manikandan
Published: February 2023

A production-inventory system with the item produced being admitted (added to the inventory) with probability δ as well as an item from the inventory supplied to the customer with probability γ at the end of a service, is considered in this paper. The (s, S) control policy is followed. We obtain the joint distribution of the number of customers and the number of items in the inventory as the product of their marginals under the assumption that customers do not join when the inventory level is zero. Performance measures that impact the system are obtained. A few level-crossing results are derived. In particular optimal pairs (s, S) are obtained through numerical procedures for values of (γ, δ) on the set {0.1, 0.2, . . . , 1} × {0.1, 0.2, . . . , 1} . A comparison of the performance measures for a few (γ, δ) pair values is provided. Finally, we discuss the first emptiness time distribution for the M/M/1/1 production-inventory system.
Empirical analysis of machine learning-based energy efficient cloud load balancing architectures: a quantitative perspective
Authors: Singh K.R. , Gaikwad A.D. , Kamble S.D.
Published: February 2023

Design of energy efficient load balancing models in cloud environments requires in-depth analysis of the cloud architecture and nature of requests served by the cloud. Depending upon these parameters, machine learning models are designed which aim at assigning best possible resource combination to serve the given tasks. This assignment varies w.r.t. multiple task and cloud parameters; which include task time, virtual machine (VM) performance, task deadline, energy consumption, etc. In order to perform this task, a wide variety of algorithms are developed by researchers cloud designers. Each of these algorithms aim at optimizing certain load balancing related parameters; for instance, a Genetic Algorithm (GA) designed for optimization of VM utilization might not consider task deadline before task allocation to the VMs. While, algorithms aimed at performing deadline aware load balancing might not provide effective cloud-to-task-mapping before allocation of tasks. Thus, it becomes difficult for researchers to select the best possible algorithms for their cloud deployment. In order to reduce this ambiguity, the underlying text compares different energy efficient cloud load balancing algorithms; and evaluates their performance in terms of computational complexity, and relative energy efficiency. This performance evaluation is further extended via inter architecture comparison; in order to evaluate the most optimum load balancer implementation for a given energy efficient application. Thus, after referring this text, researchers and cloud system designers will be able to select optimum algorithmic implementations for their given deployment. This will assist in reducing cloud deployment delay, and improving application specific load balancer performance.
Role of frame structure in the development of KRS for learning dialogues.
Authors: Singh Harjit
Published: February 2023

Dialogues are building blocks of tasks and non-tasks of communication, which happen between objects in the universe. Each dialogue is a source of linguistic knowledge within a natural language that explains and elaborates with frame structure in general. In this paper, it is noticed that various forms like (nouns, pronouns, yes-no questions and deletion) are essential part of each dialogue structure (DSS) in Chandan’s work ਜੜਾਂ/Roots. With the help of frames, knowledge representation system (KRS) is prepared for such dialogues in Punjabi. On the other hand, it is argued that highest numbers of nouns are total 45 in DS2 and only 1 deletion case finds in DS3. While DS1 and DS2 both have similar number of 2-2 cases of yes-no questions. The overall evaluation is successfully matched with proposed an algorithm based on frames.
Analysis is a discrete time queueing-inventory model with back-order of items
Authors: Anilkumar M. P. , Jose K. P.
Published: February 2023

This paper analyses a discrete-time (s, S) queueing inventory model with service time and back-order in inventory. The arrival of customers is assumed to be the Bernoulli process. Service time follows a geometric distribution. As soon as the inventory level reaches a pre-assigned level due to demands, an order for replenishment is placed. Replenishment time also follows a geometric distribution. When the inventory level reduces to zero due to the service of customers or non-replenishment of items, a maximum of k customers are allowed in the system and the remaining customers are assumed to be completely lost till the replenishment. Matrix-Analytic Method (MAM) is used to analyze the model. Stability conditions, various performance measures of the system, waiting-time distribution and reorder-time distribution are obtained. Numerical experiments are also incorporated.
Fixed point theorems in the generalized rational type of C-class functions in b-metric spaces with Application to Integral Equation
Authors: Mehdi Asadi , Mehdi Afshar
Published: February 2023

In this paper, we study some results of existence and uniqueness of fixed points for a C-class of mappings satisfying an inequality of rational type in b-metric spaces. After definition of C-class functions covering a large class of contractive conditions by Ansari [2]. Our results extend very recent results in the literature; as well as Khan in [14] and later Fisher in [9] gave a revised improved version of Khan’s result and Piri in [17] a new generalization of Khan’s Theorem. At the end, we present an example of finding solutions for an integral equation.
Concavity Method: A concise survey
Authors: Narayanan Lakshmipriya , Soundararajan Gnanavel
Published: February 2023

This short review article discusses the concavity method, one of the most effective ways to deal with parabolic equations with unbounded solutions in finite time. If the solution ceases to exist for some time, we say it blows up. The solution or some of its derivatives become singular depending on the equation. We focus on situations where the solution becomes unbounded in finite time, and our objective is to review some of the key blowup theory papers utilising the concavity method.
Dynamics of Sofic Shifts
Authors: Akbar Kamaludheen Ali
Published: February 2023

In this paper, we provide a characterization for the subshifts of finite type (SFT) in terms of Cellular automata (CA). In addition, we prove that 1. The following are equivalent for a non-singleton subshift of finite type XF. a) XF is transitive and Per(XF), the set of periodic points of XF, is cofinite b) XF is weak mixing c) XF is mixing. 2. For non-singleton sofic shifts, only the statements (a) and (b) are equivalent.
Verification of role of data scanning direction in image compression using fuzzy composition operations
Authors: Paikrao Prashant , Doye Dharmapal , Bhalerao Milind , Vaidya Madhav
Published: February 2023

A digital image is a numerical representation of visual perception that can be manipulated according to specifications. In order to reduce the cost of storage and transmission, digital images are compressed. Depending upon the quality of reconstruction, compression methods are categorized as Lossy and Lossless compression. The lossless image compression techniques, where the exact recovery of data is possible, is the most challenging task considering the tradeoff between the compression ratio achieved and the quality of reconstruction. The inherent data redundancies like interpixel redundancy and coding redundancy in the image are exploited for this purpose. The interpixel redundancy is treated by decorrelation using Run-length Encoding, Predictive Coding, and other Transformation Coding techniques. While entropy-based coding can be achieved using Huffman codes, arithmetic codes, and the LZW algorithm, which eliminates the coding redundancy. During the implementation of these sequential coding algorithms, the direction used for data scanning plays an important role. A study of various image compression techniques using sequential coding schemes is presented in this paper. The experimentation on 100 gray-level images comprising 10 different classes is carried out to understand the effect of the direction of scanning of data on its compressibility. Depending upon this study the interrelation between the maximum length of the Run and compression achieved similarly the resultant number of Tuples and compression achieved is reported. Considering the fuzzy nature of these relations, fuzzy composition operations like max-min, min-max, and max-mean compositions are used for decision-making. In this way, a rational comment on which data scanning direction is suitable for a particular class of images is made in the conclusion.
Apoyo en los trabajos de investigación para el incremento de titulados por la modalidad de sustentación de tesis
Authors: Vega Huerta Hugo , Moquillaza Henríquez Santiago , Benito Pacheco Oscar , Vélez de Villa Percy De La Cruz
Published: February 2023

Según los compendios estadísticos publicados en la página web de Universidad Nacional Mayor de San Marcos por la Oficina General de Planificación, en la facultad de Ingeniería de Sistemas e Informática la cantidad de titulados por la modalidad de sustentación de tesis es inferior al 20% de la cantidad total de titulados, esto significa que más de 80% se titula mediante otras modalidades no vinculantes a la investigación. La consecuencia es la baja cantidad de tesis producidas, por ello, el objetivo de la presente investigación es incrementar el porcentaje de titulados por tesis en la facultad de Ingeniería de Sistemas e Informática mediante un apoyo extraordinario, por parte de los docentes, en las asesorías de los trabajos de investigación de los estudiantes. El proyecto se implementó durante los años 2015 y 2016 y como resultado se obtuvo un incremento del 72% de titulados por la modalidad de sustentación de tesis.
El triple picado en el clarinete. Uso de las tecnologías para el aumento de velocidad
Authors: Marín Conesa Isabel , Marín Conesa María Belén , Marín Conesa Ester , Conesa Ferrer María Belén
Published: February 2023

El triple picado es una técnica que instrumentos como el clarinete no suelen utilizar, pero que consiste en tocar notas picadas a mucha velocidad. El instrumento parece ofrecer resistencia ante la necesidad de la vibración de la caña para producir sonido. El objetivo es demostrar que la técnica puede interpretarse a altas velocidades en este instrumento gracias a las TIC. Se recogió una muestra de 13 clarinetistas con nivel mínimo de Grado Profesional. La prueba inicial consistió en grabar 2 ejercicios (con Audacity). Esta se repitió tras 6 semanas de estudio para comprobar si existía evolución. En este periodo, los participantes estudiaron 11 ejercicios (escritos con Sibelius7) utilizando el software ZyMi. Se mantuvo la calidad examinando los espectrogramas con Sonic Visualiser. El resultado obtenido en la primera grabación fueron velocidades muy bajas (entre 32 y 75). Los participantes encontraron dificultades principalmente en los dos registros superiores. En cambio, en la última grabación, 7 clarinetistas lograron duplicar los tempi, 5 la quintuplicaron y sólo 1 la disminuyó en el segundo ejercicio porque no pudo dedicar tiempo en la última fase de estudio a practicar la técnica. Además, mejoraron colateralmente otros aspectos como la estabilidad de la pulsación al utilizar el software ZyMi y mejoraron la emisión de aire y la sonoridad al trabajar con Sonic Visualiser. Finalmente, del estudio se concluye que el aumento de tempo de la técnica sí es posible al utilizar las TIC pues permite medir exactamente cuánto asciende la velocidad y la calidad de los ejercicios.
Fixed point theorems for suzuki nonexpansive mappings in banach spaces
Authors: Sebastian John , Pulickakunnel Shaini
Published: February 2023

In this paper, we investigate the existence of fixed points for Suzuki nonexpansive mappings in the setting of Banach spaces using the asymptotic center technique. We also establish the convergence of regular approximate fixed point sequence to the fixed points of Suzuki nonexpansive mappings. Examples are also given to illustrate the results. Our theorems generalize several results in the literature.
RFM analysis for customer segmentation using machine learning: a survey of a decade of research
Authors: Chavhan Sushilkumar , Dharmik R. C. , Jain Sachin , Kamble Ketan
Published: February 2023

Customer segmentation is a method of categorizing corporate clients into groups based on shared characteristics. In this study, we looked at the different customer segmentation methods and execute RFM analysis by using various clustering algorithms. Based on RFM values (Recent, Frequency, and Cost) of customers, the successful classification of company customers is divided into groups with comparable behaviors. Customer retention is thought to be more significant than acquiring new clients are analyzed on two different databases. Results show the significance of each method. Comparison is helps for selection of better customer segmentation.
Performance analysis of NOMA in Rayleigh and Nakagami Fading channel
Authors: N. Thakre Prasheel , Pokle Sanjay , Deshpande Radhika , Paraskar Samruddhi , Sinha Shashwat , Lalwani Yash
Published: February 2023

Cellular connectivity is expanding rapidly in the modern world. The multiple access strategy is one of the highly used methods for allocating the range of users in cellular network. Spectrum allocation is a crucial element to take into account since cellular communication is becoming more and more popular. NOMA is a channel access mechanism used in 5G mobile communication. It is also known as non-orthogonal multiple access. NOMA is a potential strategy for enhancing spectral efficiency and sum rate. Using the NOMA method, we evaluated the BER versus transmitted power of two users in rayleigh and nakagami fading channels. In this NOMA setup, a single antenna is shared by two users. Two users can accept the same frequency using 5G NOMA technology, but at different power levels. The results of the MATLAB simulation show that the two user NOMA in the Nakagami channel performs better than the Rayleigh channel in terms of Bit Error Rate vs. Transmitted Power.
The Supreme Court Corrects a Seventy-Five-Year Distortion in Establishment Clause Jurisprudence
Authors: Garry Patrick M.
Published: February 2023

In Kennedy v. Bremerton School District,1 the U.S. Supreme Court ruled that the Establishment Clause did not prohibit a high school football coach from offering a brief mid-field prayer at the conclusion of games. The Ninth Circuit had held that the coach’s free exercise rights had to yield to the Establishment Clause’s prohibition of conduct that might reflect a state endorsement of religion. In overturning the Ninth Circuit, the Supreme Court issued an historic and far-reaching ruling on the scope and nature of the Establishment Clause, providing the first truly clarifying decision in this area in the past seventy-five years. The Court held that the Establishment and Free Exercise Clauses were not in tension and that the Establishment Clause could not be used to limit theFree Exercise Clause. Even more profoundly, the Court rejected the use of tests that over time had become hostile to religious liberty. Finally, the Court stated that it would decide future Establishment Clause cases by consulting the historical meaning of the Clause. This Article analyzes the future impact that the Kennedy decision will exert on Establishment Clause jurisprudence.
The Unhappening of Heart Disease
Authors: Silverstein H.
Published: February 2023

Most of the major diseases, and atherosclerotic cardiovascular disease (ASCVD) in particular, are made to happen by patient actions. Relevantly, it has been said that 95% of ASCVD, diabetes, hypertension and lipid disorders are curable: made to unhappen. Cardiovascular disease (CVD) is the leading cause of mortality and morbidity in industrialized countries including the United States. Healthcare inflicts a significant societal burden in terms of cost, and accounts for one-fifth of the gross domestic product expenditure in the United States. CVD is a disease primarily brought on by lifestyle factors, underlying genetic susceptibility becoming manifest in time (aging). Given the significant burden of health care, a major focus is now on the preventive aspects to reduce the incidence and prevalence of not only CVD, but multiple other diseases. Most diseases occur if, and ONLY if, the person with a particular genetic tendency does what is necessary to express that genetic tendency. The American public has the same genetic make-up as all other populations, but our behavioral patterns are what have activated our disease-causing genes, resulting in the major diseases and costs of our culture. By changing our behaviors, we can prevent the expression of those genetically-originated and behaviorally induced medical conditions and costs. This includes the basic requirements: clean air, clean water, a 90+% minimally-processed, high-fiber and ideally organic whole foods, diet with any pleasure-generating food once in a while, exercise to the point of developing abdominal clear lines of definition and demarcation, and the avoidance of unrealistic expectations. This article provides the Preventive Medicine Center’s (PMC) philosophy and outlines guidelines that would lead to significant regression of ASCVD and reduce the disease burden in our communities as a whole. These recommendations are an invitation to consider and provide the reasonable probability of freeing the patient from the risk of disease by the “unhappening” of (heart) disease.
Stakeholder Engagement to Drive Iterative Software Development of the ART-Access Web-Based Application for Community Pharmacy Dispensing of Anti-Retroviral Therapy
Authors: Kyomugisha Eunice , Balaba Martin , Nakibuuka Eva , King Rachel , Parkes-Ratanshi Rosalind
Published: February 2023

Introduction: Significant advances in combination anti-retroviral therapy have been instrumental in improving the quality of lives and life expectancy for people living with HIV. However, in the absence of a cure, sustained investment and innovation is required to improve adherence and quality of life for people living with HIV. We developed ARTAccess, a web-based application that links patient information on anti-retroviral therapy and viral load to an algorithm that guides a private community pharmacist on anti-retroviral therapy refills without the need for an additional nurse in the pharmacy. The aim of this paper is to describe the present the development process of the ARTAccess application and the exploration of the perceptions about its use by end users. Methods: Between October–December 2018, we conducted a qualitative observational study to document the processes of the ART-Access™ application development. Using theoretical frameworks of participatory action research and human-centred design, we undertook structured and unstructured observations of the application development review meetings. We observed and had interactions in 12 stakeholder meetings. Three observers attended each development meeting and independently drafted a reflective narration of the transcript and separately conducted their own analyses. ARTAccess was launched in January 2019 and in March 2019, three in-depth interviews were conducted with the nurse dispensers running the refill program at the three pharmacies where ARTAccess was piloted. Results: The ARTAccess application development meetings generated emerging themes. Introduction of a mHealth application for efficiency introduced job insecurity fears of health workers which needed to be addressed, to allow for increased engagement by health worker stakeholders. Stakeholder meetings provided important perceived gaps and needs for improvement at each stage of the ARTAccess application development. The user-centred design process led to five application versions; three more than the two originally planned; the feedback on the ARTAccess application became more positive as later versions were presented to stakeholders. Conclusions: The study provides evidence that participatory action research in a human-centred design approach enhanced the application development process of a new technology for health. In resource limited settings, where digital technologies may be used to support overstretched health systems, health workers need re-assurance that digital tools being developed will not threaten their employment.
Ways to Mitigate Climate Change by Implementing Zero Emission Hospitals – A Case Report
Authors: Weimann Edda , MArts Léa
Published: February 2023

If the global healthcare system would be a country, it would be the fifth largest emitter. Hence various health care systems worldwide have committed themselves to become carbon neutral. In Europe, Germany as an economy and the German healthcare system produces by far the most emissions. This has a significant impact on the health of the population in Germany, Europe and worldwide. It leads to Disability Adjusted Life Years (DALYs) as well as premature deaths. To reduce global climate change related damages, disasters and negative health outcomes, Germany has committed itself through various treaties to become carbon neutral and to transform the healthcare system towards net zero until 2030. The article highlights crucial steps for hospitals how this can be achieved. Important management tools are the SWOT analysis, the PDCA cycle, the DHOW model and the sustainable Balanced Score Card. Hospitals should establish Key Performance Indicators for Scope 1, 2, and 3 emissions and monitor them on a monthly basis. Important action areas are energy sources, insulation of buildings, waste, water consumption, nutrition, transportation, chemicals, pharmaceuticals, climate education and leadership. Leadership should be executed as a top-down as well as a bottom-up approach to involve all relevant stakeholders including staff and patients.
Complex Trauma, Psychosis and COVID-19: A Case Report
Authors: Delgado Marlon , Vallina-Alvarado Francisco , Mawcinitt-Backmann Katherine , Toledo-Lozano Christian
Published: February 2023

Background: Complex trauma is a variant of post-traumatic stress disorder (PTSD), adding symptoms of affect dysregulation, difficulty in relationships, and negative self-perception. Its neurobiology is closely linked to the pro-inflammatory alterations by the disruption of the hypothalamic-pituitary-adrenal axis, which are also described in psychosis, and neuropsychiatric symptoms of the SARS-CoV-2 virus infection. Aim: To present a case that illustrates the clinical and neurobiological overlap between COVID-19, psychosis, and complex trauma. Case presentation: A 24-year-old female who initially presented dissociative symptoms evolving into a psychotic episode, after suffering from COVID-19 disease, in whom a history of abuse was later clarified. The clinical case is reviewed, performing a free search of articles for the discussion of clinical and pathophysiological challenges. Conclusion: Trauma is one of the greatest determinants in mental health, and is associated with several clinical spectra, being necessary to open the phenomenological and physiological debate to understand the sum of effects in patients who present with severe mental illness.
Are gastrointestinal signals the principal guides to human appetite and energy balance?
Authors: Borer Katarina
Published: February 2023

In view of the exponential rise of global obesity in the past three quarters of the century, it is useful to examine what is driving this change and what approaches can curb it. The chief drivers of weight gain are, on one hand our misunderstanding of the mechanisms controlling energy balance, and, on the other, reliance on current, potentially misleading conflicting scientific opinions and government policies regarding the controls of human appetite. This review outlines the evidence that: (1) there is no direct bioenergetic feedback from energy metabolism or energy stores to the brain mechanisms guiding feeding and energy expenditure, (2) human appetite is controlled by signals originating from an empty or full stomach, food palatability and opportunities to eat as well by the rate of food absorption, that (3) humans bear a genetic burden of having high ability and capacity to store fat and mechanisms that curb body- mass and fat loss, (4) humans are motivated to overconsume while maintaining low energy expenditure, and (5) commercial interests of food businesses marketing highly palatable foods, and wide-spread mechanization of living tasks and urban design reduce the need for physical work and movement. The non-pharmacological and non-surgical solutions to obesity involve an understanding of human genetic impediments and environmental obstacles to maintaining healthy weight, coupled with deliberate corrective or preventive behaviors, such as understanding and using gastrointestinal tract signals that provide sufficient, albeit subtle, cues for sensible food intake, and using daily weight monitoring and activity tracking devices to record and motivate healthy levels of physical activity.
Unique Characteristics of Neonatal T Cells
Authors: Kempis-Calanis L.A. , Rodríguez-Jorge O. , Ventura-Martínez C.J. , Gutiérrez-Reyna D.Y. , Spicuglia S. , Santana M.A.
Published: February 2023

Birth causes complex changes in the individual physiology and organ systems and certainly poses a big immune challenge. The sudden encounter with an antigen full world, with the exposure to food antigens, and the colonization of the skin and mucosa with microbiota, require a tolerant immune system. Nevertheless, neonates must also be able to deal with pathogens, which makes their immune system unique. T lymphocytes are responsible for the coordination of the adaptive immune system response, the elimination of infected cells and the type of immune response and memory. It has been shown that neonatal cells have intrinsic differences with adult cells, biased towards an innate response and a tolerant phenotype. In the perinatal period, the immune system changes from basal signaling and innate like responses, towards stimulus-specific signals, which increase with gestational age. After birth the cells of the immune system continue to change both in composition and function. In this review, we present the intrinsic differences of neonatal CD4+ and CD8+ T cells, as compared with adult naïve cells. A specific transcriptome profile is present in both CD4+ and CD8+ neonatal T cells, with overexpression of homeobox transcription factors. These cells also present differences in cell signaling and metabolic characteristics, which result in unique functional capabilities. Neonatal CD4+ T cells respond differently from adult cells, with a high production of IL-8, a prevalent Th2 over Th1 profile, and an innate inflammatory response. The neonatal period is one of the most vulnerable periods of life, with a high morbidity and mortality rate, approaching on average 17 deaths per 1000 live births worldwide. A better understanding of the neonatal immune system will help to ensure a better care of this vulnerable population.
Religious Elit’s Communication and Strategy in Building Attitude of Tolerance in Plural Society in the Gunungsari West Lombok
Authors: Krisdiana Putri , Misbahuddin
Published: February 2023

This article discusses the strategy of the religious elite in building tolerance for a plural society in Gunungsari, West Lombok. The main problem studied is the strategy of Islamic and Hindu religious elites in internalizing and externalizing the value of religious tolerance in a plural society in Gunungsari. The writer uses three methods to get data about the main problem: observation, interview, and documentation. After conducting an analysis using qualitative methods, the authors found that religious elites had three strategies for instilling an attitude of tolerance: (1) Islamic religious elites instilled tolerance values in Muslim communities at religious events such as recitations at mosques. Likewise, the Hindu religious elite, their religious elite instills a value of tolerance at Piodalan events at temples, (2) The religious elite of Islam and Hinduism are the example, and role models for their followers and congregations, (3) In the event of a conflict, the Muslim and Hindu religious elites look for problem points by establishing communication to obtain a fair solution for both parties.
Humanizing Patients with a Holistic Care Approach to Improve their Psycho-Social-Spiritual Conditions
Authors: Mumtahanah Silma , Khisoli Alfis Khoirul
Published: February 2023

The purpose of this study is to describe the process of spiritual guidance by implementing Holistic Health Care services performed by Bina Rohani officers in improving the patient's psycho-social-spiritual health. This qualitative research applied a descriptive analysis approach. Data collection techniques in this study were carried out by observation, in-depth interviews, and document review. The results of this study show that Bina Rohani plays a role in improving the psycho-social-spiritual health of patients side by side with nursing assessments using Holistic Health Care services. This is evidenced by positive changes in patients who experience problems in the psycho-social-spiritual aspect so that patients can worship, pray and read verses, have a feeling of peace, accept illness, and be ready to return to society without feeling inferior. The process of implementing spiritual guidance with Holistic Health Care services is carried out by spiritual development officers based on established Standard Operating Procedures (SOP).
Standardization & evaluation of anti-oxidant, anti-inflammatory and antimicrobial potential of Panchnimba Churna
Authors: Meena Ajay Kumar , Rajput Sanjana , Chaturvedi Sadhana , Parashar Deepesh , Sharma Lavkush
Published: February 2023

: Ayurvedic medication pancha nimba choorna is a herbal powder. The panchanimba is a well-known medication stated in the old Ayurvedic texts used to cure kshudra kushtas (minor skin disorders), such as eczema, acne, and Maha kushtas (major skin ailments).It is used to treat a variety of skin conditions, including dermatitis, pruritis, psoriasis, sinus, non-healing wounds, headaches, uti, diabetes, toxins, and arthritis. It is employed to treat infections of the skin.

The traditional use of the neem tree's leaves, blossoms, seeds, fruits, roots, and bark for the treatment of inflammation, infections, fever, skin conditions, and dental problems includes all of these parts. Neem leaf's therapeutic benefits have been specifically discussed. The immunomodulatory, anti-inflammatory, anti-hyperglycaemic, antiulcer, antimalarial, antifungal, antibacterial, antiviral, antioxidant, antimutagenic, and anticarcinogenic activities of neem leaf and its components have been proven. Protein, carbohydrates, flavonoids, phenol, saponin, glycosides, tannin, and alkaloids are all present according to phytochemical analysis, whereas terpenoids, sterols, and other substances are not present.

To guarantee the quality of the product, standardization employing various parameters was used which was performed as per the Indian Pharmacopoeia, WHO guidelines and various literature reports. The antioxidant activity may be attributes to flavonoids and phenolics present in extracts of . In terms of gallic acid equivalent, Panchanimb Churna contained 105 mg/g of total phenols and the total flavonoid concentration was 43.8214 mg/g, which is the quercetin equivalent.Antioxidant property was evaluated using DPPH activity.

According to a forementioned quality criterion, Panchanimb Churna was determined to be competent under every examined aspect. The current study strengthens belief in herbal remedies of natural origin to combat infectious diseases and other illnesses that may be included in medications in the future. Overall the product is very beneficicial in day to day life for humans as it possess various qualities and activities.
Pattern and outcome of obstetric patients admitted in the medical critical care unit of tertiary care hospital
Authors: Shetti Akshaya Narayan , Patel Arush , Mustilwar Rachita G
Published: February 2023

Various types of diseases are seen in pregnant patients, it may be prior to the pregnancy or during the pregnancy period. Certain diseases may lead to critical care admission and may be either elective or emergency admission.

This study was conducted to know the pattern and outcome of obstetric patients getting admitted to the medical critical care unit of our tertiary care hospital.

This is a retrospective study, and we collected the data from the records for two years duration, starting from 1st January 2020 to 31st December 2021.

A total of 97 patients were admitted and a maximum number of patients were aged between 18-25 years. 56(57.7%) of patients were primigravida, and 58(59.8%) of the patients were registered cases. 82(84.5%) of cases were registered under the medico-legal case as per Indian law. 68(70.1%) patients had lower segment cesarean sections. Among 97 patients, 22(22.7%) of patients had comorbid illnesses. A total of 22(22.7%) patients got admitted for poisoning-related issues, which was the single most common cause among 97 admissions. 25(25.8%) of patients were on mechanical ventilation and the average number of critical care unit stay was 4 days. 65(67%) patients survived, 15(15.5%) patients died, and the remaining patient was either took discharged against the advice or referred.

Obstetric patient admission in the rural critical care unit is not uncommon, and poisoning is the most common cause of admission in the medical critical care unit.
The characterization of the electronic state of transition metal ions occuring in the Li1 + xNi1 / 3Co1 / 3Mn1 / 3O2 by magnetic methods
Authors:   Institute of Chemistry of a Solid body UB of RAS, Semenova A. S. , Melkozerova M. A. ,   Institute of Chemistry of a Solid body UB of RAS, Zabolotskaya E. V. ,   Institute of Chemistry of a Solid body UB of RAS, Kellerman D. G. ,   Institute of Chemistry of a Solid body UB of RAS, Kosova N. V. ,   Institute of Chemistry of a Solid body and Mechanochemistry of the Siberian Branch of RAS, Devyatkina E. T. ,   Institute of Chemistry of a Solid body and Mechanochemistry of the Siberian Branch of RAS
Published: February 2023

The complex oxides Li1 + xNi1 / 3Co1 / 3Mn1 / 3O2 were obtained by solid state method. The conclusion about influence of lithium concentration on Ni2+ and Ni3+ ions ratio in Li1 + xNi1 / 3Co1 / 3Mn1 / 3O2 is made. Monotonous decrease of g-factor value identified by EPR method testifies the intensification of local exchange interactions with temperature descent. That is in agreement with magnetic susceptibility data indicating the antiferromagnetic ordering at T=4 K.
Calculation of structures of low-melting electrolits in threefold salt systems
Authors:   Samara State Technical University, Garkushin Ivan Kirillovich , Gubanova Tat'yana Valer'evna ,   Samara State Technical University, Frolov Evgenii Igorevich ,   Samara State Technical University, Moshchenskaya E. Yu. ,   Samara State Technical University, Batalov Nikolai Nikolaevich ,   Institute of high-temperature Electrochemistry UB of RAS, Zakharov V. V. ,   Institute of high-temperature Electrochemistry UB of RAS
Published: February 2023

Melts based on lithium salts are applied in various branches of engineering and scientific research. This requires improved methods to search for low-melting compounds and data on phase equilibria in systems of three or more components. We developed computational and experimental method for determining the composition of ternary eutectic for inorganic systems, which is tested on twenty systems of lithium salts, as well as three-component systems containing lithium iodide.