bluuebunny/crossref_metadata_2025 huggingface dataset:
The Authenticity Concept of Sh. Zukin: “Schizoid” Category in Urban Studies
Authors: Kalashnikova Kseniia N.
Published: June 2020

The article is devoted to the consideration of the concept of authenticity set forth by S. Zukin in the book “Naked City: Death and Life of Authentic Urban Spaces”. The sources of the concept are traced in the author’s early works, the main subjects described in them are: the process of gentrification; power relations forming the urban landscape; symbolic economy and the power of cultural characteristics. These subjects became the basis of the idea of authenticity. Its manifestations are described by the example of “uncommon” and “common” urban spaces. A separate place in the article is considered by the development of individual ideas of Sh. Zukin, their interpretations, as well as applications for specific studies in the work of followers. The conclusion is drawn about the variety of interpretations offered by researchers and the ambiguity of using authenticity as a tool for analyzing the city.
Information support and promotion of chemistry in the USSR
Authors: Vaganov Andrey G.
Published: June 2020

The effectiveness of the implementation of large-scale socio-economic, technological and scientific programs and projects largely depends on how easily and organically these ideas will be accepted by society. Of course, it will be an exaggeration to say that this is what determines the success or failure of certain socio-economic projects in the USSR. But to neglect and ignore the influence of this factor would be a big mistake.The article examines in detail one of the largest (and one of the last) campaigns of scientific popularization – “chemicalization of the national economy of the USSR”. When analyzing the campaign to popularize and promote chemicalization (late 1950s – early 1980s) in order to understand the logic of its origin, rise and fall, it was necessary to consider the media support of a similar campaign in the USSR in the 1920–1930s. As a result, three waves of this kind of propaganda campaigns have been identified, with those going on with a damped amplitude.The author made an attempt to show how, from the very beginning of the institutionalization of this program, its initiators provided for powerful informational support. Methods and tools have been allocated that the state has primarily resorted to during the chemicalization process throughout the entire period under review. The continuity of these approaches is traced. It is noted that as one of the key moments of the program for the chemicalization of the national economy in the USSR, initially, almost immediately after the end of the Civil War, the Soviet leadership assumed the development of not only applied (primarily related to defense tasks) aspects of chemicalization, but also fundamental chemical science. And all this was accompanied by widespread media support. Moreover, given the scarce resources of the state in the 1920s, the most effective strategy in those conditions was chosen: the “chemicalization” of public education, school and university.Using a wealth of factual material, using the capabilities of computer statistical analysis and rare bibliographic copies of books and periodicals, it was possible to trace the dynamics of the process of popularizing chemical knowledge in Soviet society.
On the return of the professionals to the governance of science
Authors: Semenov Evgeny V.
Published: June 2020

The learning system should be smarter than the one being studied, the control system should be at least no more stupid than the control object. The governance of such an object as science implies an extremely high level of intelligence and professionalism of managerial personnel. The achievement of such level of professionalism and its maintenance requires considerable continuous efforts. But the entire thirty-years post-Soviet period of Russian history is characterized by a progressive decline of the professionalism of personnel in the science governance system. The process of personnel degradation of the Ministry of Science is inextricably linked with its chaotic reorganization that has been ongoing all this time. Based on the author’s personal observations throughout this period, the article analyzes the process of successive loss of professionalism during the permanent reorganization of the Ministry. A possible way of reviving the professional governance of science in the country is substantiated on the basis of awareness by the state leaders of the importance of this task and firm decision-making. The necessity of linking the personnel policy to a large real task of national importance, which for Russia at present time is the need to overcome the growing technological gap and the growing technological dependence of the country, is substantiated.The fundamental importance of the leader, whose potential will be adequate to the complexity of the existing problems and tasks, and which can be capable to form a management team and to create a professional governance environment at all levels and in all segments of governance of science, is substantiated.
Visibility of scientific results Green Open Access in institutional repositories
Authors: Valeeva Marina V.
Published: June 2020

Open access gives free access to research publications and today, about 23% of scientific publications in Russia are in the public domain. How and to what extent an open access publication affects citation - issues that have been the subject of debate for quite some time, and of course, the type of open access in which the article is posted plays an important role here. Now, the most common are the “golden” and “green” types of open access, each of which has both advantages and disadvantages. The article presents the results of a study conducted in 2018, during which the degree of using the capabilities of Gold Open Access and Green Open Access by universities of the 5-100 project, as well as Moscow State University, St. Petersburg State University and the RAS institutes (namely, the Ural Branch of the RAS and the SB RAS). The analysis included articles located in Scopus - Gold Open Access and Green Open Access. Also, as part of the study, the authors analyzed the case of the Ural Federal University named after B.N. Yeltsin, in the framework of which the success of the institutional repository was evaluated Electronic scientific archive of Ural Federal University (elar.urfu).
The role of scientific schools in the organization of native radiophysics
Authors: Kudryavtsev Vasily V. , Chulkova Galina M.
Published: June 2020

The article describes the scientific-school approach as a method of historical and scientificresearch. The value of the scientific-school approach in relation to the study of domesticscience is revealed. Based on the consideration of new «dimensions» (or aspects) ofscience, a researcher can get a panoramic picture of its development in a scientifically-substantive,scientific-organizational, scientific-educational, personal-psychological and sociocultural«dimensions». A brief historical review is given, fixing some important milestones onthe path to the formation of the first Soviet scientific schools in physics. These schools played a fundamental role in the organization and development of physical science in our countryafter the October Revolution. The reasons for the loss of the role of scientific schools in the organizationof modern scientific research abroad are discussed. It is shown that the evolutionof Russian radiophysics is closely related to the activities of a number of scientific schools.Various «roles» of scientific schools that they played in the emergence of native radiophysics,the creation of its theoretical foundation, the formation of new areas of radiophysical research,the development of information transfer technologies, military technologies with a significantradiophysical component, the formation of modern educational and scientific radiophysicalcenters are examined. These «roles» may be useful in organizing research in our country.
The value of the national language of science (part no. 1)
Authors: Donskikh Oleg A.
Published: June 2020

The article examines the history of the formation of several languages of science – Ancient Greek, Sanskrit, Arabic and Latin - relating to the material of four languages and corresponding cultures. Several considerations are given in favor of the need to preserve the national languages of science. The stages of formation of languages of science in the system of culture are traced. There are two types of languages that are used by scientific communities: 1) languages that are rooted in the national culture and remain firmly linked with the natural language community; 2) languages that are reserved for performing a certain function, while in parallel, national languages are fully functioning in society. The first type includes the Greek and Arabic, the scientific languages of the second type are Sanskrit and Latin. The key role of the humanitarian, in particular poetic, philological and philosophical culture for the formation of the language of science is shown. Based on the material of the Ancient Greek language, the stages of its development over several centuries are traced, which resulted in such linguistic tools that allowed not only to use abstract conceptual concepts, but also to organize the vocabulary hierarchically, and this as a result allowed to form any needed generic chains. The importance of the appearance of impersonal texts that comes with collections of written documents alienated from a particular teacher is emphasized.
Resiliensi pada Remaja Tunadaksa yang Mengalami Bullying
Authors: Oviyanti Melinda , Hendriani Wiwin
Published: June 2020

Penelitian ini bertujuan untuk mengetahui gambaran resiliensi yang ditinjau dari teori Grotberg. Sumber resiliensi, sebagaimana dinyatakan oleh Grotberg, dibagi menjadi 3 dimana terdapat sumber I am, I have, dan I can. Metode penelitian ini menggunakan pendekatan kualitatif dengan tipe penelitian studi kasus intrinsik. Pemilihan partisipan menggunakan purposive sampling dengan metode screening resilience. Partisipan berjumlah 3 remaja perempuan yang terdiri dari seorang remaja berusia 14 tahun dan 2 remaja berusia 15 tahun. Proses pengambilan data menggunakan wawancara dan dianalisis menggunakan analisis tematik theory-driven. Hasil penelitian ini menunjukkan bahwa ketiga partisipan memiliki bentuk coping stress yang berbeda untuk menuju resiliensi. Partisipan 3 memiliki resiliensi paling menonjol di antara partisipan lain, dan meskipun terdapat banyak adversity yang dialami, partisipan 3 menunjukkan resiliensi yang tinggi melalui indikator I am. This study aimed to overview the Grotberg's resilience theory. The source of resilience, as stated by Grotberg, is divided into 3 which include "I am", "I have", and "I can". This was qualitative intrinsic case study. The participants were chosen by purposive sampling with resilience screening methods. There were 3 female adolescent participants; one aged 14 years old and the other two aged 15 years old. The data were collected using interviews and analyzed using theory-driven thematic analysis. The result of this study indicated that the participants had different forms of coping stress towards resilience. Participant 3 was the most prominent among other participants, and although participant 3 experienced adversity, the participant demonstrated a high resilience as evidenced through the "I am" indicator.
Etos Kerja Pada Anggota Kepolisian Ditinjau dari Persepsi Dukungan Organisasi dan Dukungan Sosial Keluarga
Authors: Permata Ekshalanty , Priyatama Aditya Nanda , Satwika Pratista Arya
Published: June 2020

ABSTRAKPenelitian ini bertujuan untuk mengetahui: 1) hubungan antara persepsi dukungan organisasi dan dukungan sosial keluarga dengan etos kerja, 2) hubungan persepsi dukungan organisasi dengan etos kerja,  3) hubungan dukungan sosial keluarga dengan etos kerja. Sampel penelitian ini berjumlah 61 orang anggota kepolisian. Pengambilan sampel dalam penelitian ini menggunakan cluster random sampling. Penelitian ini menggunakan metode kuantitatif. Analisis data penelitian dilakukan menggunakan analisis regresi ganda. Hasil penelitian ini menunjukkan nilai F(61)=27.420, df=2, nilai p=.000, R=.697, yang berarti terdapat hubungan positif yang signifikan antara persepsi dukungan organisasi dan dukungan sosial keluarga dengan etos kerja. Secara parsial, terdapat hubungan positif yang signifikan antara persepsi dukungan organisasi dengan etos kerja (rx|y= 0,410; p=0,001) dan terdapat hubungan positif yang signifikan antara dukungan sosial keluarga dengan etos kerja (rx|y= 0,334; p=0,009). Nilai R2 dalam penelitian ini menunjukkan bahwa persepsi dukungan organisasi dan dukungan sosial keluarga secara bersama-sama memberikan sumbangan efektif sebesar 48,6% terhadap etos kerja.Kata kunci: dukungan sosial keluarga, etos kerja, persepsi dukungan organisasi                                                                                                                                                                                ABSTRACTThis study aims to identify: 1) relation between perceived organizational support and family social support with work ethos, 2) relation between perceived organizational support with work ethos 3) relation between family social support with work ethos. This study was conducted on 61 active police department officers, selected by using cluster random sampling method. This study was using quantitative approach. Data analysis used multiple regression analysis technique. Result shows the score of F(61)=27.420, df=2, p=.000, R=.697, which means that there is a significant, positive correlation between perceived organizational support and family social support with work ethos. Partially, there is a significant, positive correlation between perceived organizational support with work ethos (rx|y= 0,410; p=0,001 < 0,05) and also between family social support with work ethos (rx|y= 0,334; p=0,009 < 0,05). R2 score shows that both perceived organizational support and family social support give effective contribution until 48,6% to work ethos. Keywords: family social support, perceived organizational support, work ethos
Respon Kedelai Hitam terhadap Berbagai Jenis Pupuk Organik
Authors: Ralle Andi , Subaedah St
Published: June 2020

Increased productivity of black soybeans continues to be pursued by improving appropriate cultivation technologies, including by providing organic fertilizer. This research aimed to assessing the response of growth and production of black soybean plants to various types of organic fertilizers. The study was conducted in the form of a field experiment in Gowa Regency from March-June 2019. The experiment was designed with a randomized completed block design consisting of four treatments, namely: without organic fertilizer, organic fertilizer from rice straw, organic fertilizer from banana stems and organic fertilizer from gamal leaves. Each treatment was repeated four times, so as to get 16 experimental units. The parameters observed were plant height, number of pods per plant, pod weight per plant and pod weight per plot. The results showed that the administration of organic fertilizers obtained better growth and production of black soybeans. Fertilization with organic fertilizer from Gamal leaves obtained the highest yield of black soybean seeds, 2.46 tons ha-1.
Efektivitas Pupuk Organik dan Interval Penyiraman terhadap Pertumbuhan dan Produksi Tomat
Authors: Fateha Riska Nur , Ilhaminnur Bait , Soemarno Soemarno , Wandansari Niken Rani
Published: June 2020

This research aimed to determine the effect of various organic fertilizer and watering intervals on plant growth and tomato yield, also soil nutrient content. The method used was factorial completely randomized design with a combination of organic fertilizer types (kaliandra compost, water hyacinth and Mexican sunflower compost, cow manure and straw compost, and vermicompost) and watering intervals (1, 3 and 7 days). Mycorrhizal dose used was 2 grams/plant, while organic fertilizer used was 160 g/plant. The results showed that the interaction between organic fertilizer and watering intervals did not affected significantly on tomato plant height, stem diameter, root length, initial flowering, fruit diameter, number of fruits and fresh fruit weight and soil nutrient content. Watering interval affected significantly to all parameters of the observation. Addition of organic fertilizer can increase soil C-organic content by 6.58% and P-available by 170.51% compared to controls. In general, the highest tomato production was obtained in the combination of treatments water hyacinth and Mexican sunflower compost and watering interval of 1 day, which was 231 g/plant or equivalent 7.22 tons/ha.
PENGARUH PEMOTONGAN BUNGA, PUCUK DAN PENGHENTIAN PENAMBAHAN CAHAYA PADA TANAMAN MENTHA (Mentha piperita L.)
Authors: ROSMAN ROSIHAN , HARJAD SRI SETYATI , SUDIATSO SUGENG , YAHYA SUDIRMAN , PURWOKO BAMBANG SAPTA , CHAIRUL CHAIRUL
Published: June 2020

ABSTRAK
Penelitian bertujuan mengkaji pengaruh pemotongan bunga, pucuk
dan penghentian pencahayaan pada tanaman M. piperita L. Penelitian
dilakukan di Instalasi Penelitian Lembang, Balai Penelitian Tanaman
Rempah dan Obat, Jawa Barat, dari bulan Januari sampai Juli 2000, dalam
dua tahap : tahap pertama membuat variasi lingkungan cahaya dan habitus
tanaman, dan tahap kedua penyulingan dan analisis komponen minyak
dengan kromatografi gas spektrometer massa. Penelitian menggunakan
tanaman yang tidak berbunga akibat panjang hari normal dan tanaman
berbunga akibat penambahan cahaya empat jam, pukul 18.00-22.00 mulai
umur 30 hari. Penelitian menggunakan rancangan acak kelompok 5
perlakuan, yaitu B 0 (tanaman berbunga dibiarkan), B 1 (tanaman berbunga
dipotong bunganya), B 2 (tanaman berbunga diletakkan pada kondisi
normal), B 3  (tanaman tidak berbunga dibiarkan), dan B 4 (tanaman tidak
berbunga dipotong pucuk). Hasil penelitian menunjukkan bahwa
pemotongan bunga meningkatkan mentol dan menekan menthofuran.
Penghentian penambahan cahaya 4 jam pada tanaman berbunga
menjadikan tanaman merunduk, kadar mentol menurun dan menthofuran
meningkat. Pemotongan pucuk dapat menurunkan kandungan mentol dan
meningkatkan kandungan menthofuran.
Kata kunci : Mentha, Mentha piperita L., pemotongan bunga, pucuk,
pencahayaan, kandungan mentol, kandungan menthofuran

ABSTRACT
The effect of inflorescent pinching , bud pinching, and
normal light period on peppermint (Mentha piperita L)
Experiment on the effect of pinching the inflorescent, pinching the
bud, and normal light period on peppermint (Mentha piperita L) was
carried out at the experimental garden Lembang of Research Institute for
Spice and Medicinal Crops, West Java, from January to July, 2000. The
study was conducted with two steps i.e. The first step was manipulation of
photo period using TL lamps and the second step was distillation and
analisis of peppermint oil from their products with gas chromatography
and mass spectrometry. The experiment, 5 treatments were given i.e.
using long day treated plants, 3 treatments are given i.e. control, pinching
the inflorescent and with holding light supplement (four hours light
supplement at the age of 30 days), and using control plants, 2 treaments
are given i.e. no pinching and pinching of terminal bud (control or normal
light period). The result showed that pinching the inflorescent elevate the
menthol and reduce the menthofuran content. Pinching the bud of non
flowering plants can reduce the menthol and increase the menthofuran
content.
Key words : Peppermint, Mentha piperita L, inflorescent pinching, bud,
pinching, light period, menthol content, menthofuran content
PENGARUH PUPUK MAJEMUK TERHADAP HASIL DAN MUTU TEMBAKAU VIRGINIA DI BONDOWOSO, JAWA TIMUR
Authors: DJAJADI DJAJADI
Published: June 2020

ABSTRAK
Untuk mengetahui pengaruh pupuk majemuk terhadap hasil dan
mutu tembakau virginia yang ditanam di tanah ringan, telah dilakukan
penelitian di Desa Pengarang, Kecamatan Pujer, Kabupaten Bondowoso
mulai bulan April sampai Nopember 2001. Penelitian ini menggunakan
rancangan acak kelompok dengan tiga kali ulangan untuk menyusun
perlakuan. Perlakuan yang dicoba adalah pupuk majemuk (PM) dengan
dosis 5, 6, 7, 8 dan 9 butir pertanaman dibandingkan dengan PM (dosis
masing-masing) dicampur dengan biokonsentrat. Sebagai perlakuan
pembanding adalah paket pupuk rekomendasi, yaitu 200 ZA + 200 PN +
100 SP36 + 100 ZK. Hasil penelitian menunjukkan bahwa pemberian PM
sebanyak 6 butir per tanaman (setara dengan 185 kg/ha atau 40 kg N/ha)
menghasilkan daun basah tembakau sebanyak 11,34 ton/ha. Hasil daun
basah tersebut tidak berbeda dengan hasil daun basah tertinggi (12,42
ton/ha) yang dihasilkan tanaman tembakau dengan paket dosis
rekomendasi. Dosis pupuk majemuk juga memberikan nilai indeks mutu
tertinggi (55,90) tidak berbeda pengaruhnya dengan pupuk rekomendasi.
Pemberian pupuk rekomendasi menghasilkan tanaman tembakau yang
berkadar N dan P jaringan tanaman tertinggi pada pengamatan umur
tanaman 75 hari setelah tanam dan pada saat akhir panen.
Kata kunci: Tembakau virginia, tanah ringan, pupuk, Kabupaten
Bondowoso, Jawa Timur
ABSTRACT
Effect of compound fertilizer on yield and quality of
virginia tobacco in light soil, Bondowoso, East Java
Study to determine the effect of compound fertilizer on yield and
quality of virginia tobacco was conducted in Pengarang, Pujer, Bondo-
woso District, from April to November 2001. Factorial in randomized
block design with three replicates was arranged to set the treatment
consisting of two factors. The first factor of treatment consists of two
variables, i.e. compound fertilizer (PK) and PK +bio-concentrate. The
second factor was the rates of PK, i.e 5, 6, 7, 8, and 9 tablets per plant or
equivalent to 185, 221, 258, 294 and 331 kg/ha. All the treatments were
compared to recommended fertilizer to farmers (200 ZA + 200 PN + 100
SP36 + 100 ZK kg/ha). The results showed that 185 kg/ha PK gave the
fresh tobacco yield of 11.34 tones/ha which was not significantly different
with the highest fresh tobacco leave (12.42 tones/ha) produced by
recommended fertilizer. Grade index value of tobacco produce by PK and
recommended fertilizer was not significantly different. However, virginia
tobacco with recommended fertilizer had the highest content of N and P in
plant tissues which were observed at 75 days after planting and until the
end of harvesting.
Key words: Virginia tobacco, light soil, fertilizer, Bondowoso District,
East Java
Monoclonal and polyclonal immunoglobulin G deposits on tubular basement membranes of native and pretransplant kidneys: A retrospective study
Authors: Sawada Anri , Okumi Masayoshi , Horita Shigeru , Tamura Tomomi , Taneda Sekiko , Ishida Hideki , Hattori Motoshi , Tanabe Kazunari , Nitta Kosaku , Honda Kazuho , Koike Junki , Nagashima Yoji , Shimizu Akira
Published: June 2020

BackgroundMonoclonal tubular basement membrane immune deposits (TBMID) are identified by renal biopsy and are associated with progression of interstitial injury in renal allograft. However, the significance of TBMID in the native kidney remains unclear.MethodWe retrospectively analyzed 3,126 native kidney biopsies and 1,724 zero-hour biopsies performed between 2008 and 2018 in our institution.ResultsThe rate of immunoglobulin G (IgG) TBMID was found to be 5.2 % among native kidney biopsies and 0.4 % among zero-hour biopsies. The rate of IgG TBMID was relatively common in the case of diabetic nephropathy (31.3%) and lupus nephritis (25.5%), but rare in IgA nephropathy (IgAN) (1.1%). Monoclonal IgG TBMID was identified in seven cases, including three zero-hour biopsies. The pathological diagnosis from native kidney biopsy was IgAN in two cases, antineutrophil cytoplasmic antibody-related vasculitis in one, and Focal segmental glomerulosclerosis in one. Zero-hour biopsy revealed IgAN in one case and mild atherosclerosis in two. The combination of IgG1κ was observed in two cases, IgG1λ in three, and IgG2κ in two. Interstitial injury is not severe in all cases. Electron microscopy revealed powdery electron-dense deposits. Monoclonal gammopathy of undetermined significance was diagnosed in one case with IgA nephropathy. Although One patient developed renal failure, all others exhibited stable renal function.ConclusionMonoclonal IgG TBMID in the native kidney is not associated with renal prognosis or interstitial injury. However, this could be a useful immunopathological parameter for early identification of cases requiring hematological investigation and microscopic evaluation.
Impact of the COVID-19 pandemic on orthopedic surgical practice: international study
Authors: Meraghni Nadhir , Bouyoucef Hichem , Benkaidali Riad , Hamza Amine
Published: June 2020

Purpose The purpose of this study was to assess the impact of the COVID-19 pandemic on the clinical practice in orthopedic units.Methods An online survey was sent by e-mail to orthopedic surgeons practicing in different parts of the world.Results This study showed that orthopedic surgery plan management was adapted to respond more effectively to the COVOD-19 pandemic while maintaining the continuity of health care and ensuring protection of medical staff and patients. Among the introduced measures, elective surgery was postponed to free-up beds for suspected or COVID-19 positive patients requiring hospitalization. Additionally, the number of outpatient visits was considerably decreased and non-urgent visits were postponed to reduce the flow of patients in and out of hospitals and therefore minimize the risk of contamination. Interestingly, data revealed the willingness of orthopedic surgeons to take care of COVID-19 positive patients and support their colleagues in intensive care units, if needed.Conclusions Though, orthopedic surgeons are not in the frontline, they have an important role to play to face the increasing pressure due to the Covid-19 pandemic. Based on these findings, publication of international orthopedic practice guidelines during the COVID-19 pandemic would be of great benefit to health practitioners in general and orthopedic surgeons in particular.
Influence of suture diameter on microsurgical ureterorrhaphy in rabbits: an experimental study
Authors: Peixoto Tainara Micaele Bezerra , Scheffer Jussara Peters , Mello Luciana De Macêdo , Denevitz Rodiney Pinheiro , Faes Márcia Rezende , Petronilha Mariah Bianchi Reis Gusmão , Morales Isabella Cristina , Antunes Fernanda , Oliveira André Lacerda de Abreu
Published: June 2020

Background

Ureteral obstruction is a common indication for surgical intervention, due to the small size of the ureter, specialized instrumentation is required such as operating microscope for intraoperative magnification and microsutures. The aim of this study is to evaluate and compare 3 sizes of nylon 6 − 0,8 − 0,10 − 0 for ureterorrhaphy in the ureter of rabbits, using microsurgical technique.
Results

A total of fifteen male, adults, New Zealand rabbits were divided in three groups: all groups were submitted ureterotomy. A 2 mm longitudinal incision was made in the medial portion of the right ureter, followed by a partial perforating simple interrupted 6 − 0, 8 − 0 and 10 − 0 sutures in each group. During the experiment ultrasound evaluations were performed to assess the kidney length and width, the presence of ureteral calculi, the renal pelvic dilation, the ureter diameter and the presence of free liquid in the abdominal cavity. At the end of the experiment all kidneys and ureters were submitted to macroscopic and histopathological evaluations. In the first ultrasound assessment, all groups had an acute increase in renal length (p < 0.048). The group with 8 − 0 suture showed a difference in ureteral diameter on the 5th day (p < 0.01) and all groups showed a reduction in diameter on the 30th day. The group with 6 − 0 suture showed a high mortality rate during the experimental period and the histopathological evaluation exhibited areas of necrosis. According to the ultrasound evaluation caliber 10 − 0 achieved better results in, macroscopic and microscopic evaluations. The finer suture diameters had better outcomes according to the ureteral inflammation scores.
Conclusions

The use of 10 − 0 suture resulted in lower rates of ureteral inflammation, renal changes and postoperative complications when compared to two other sizes of the same material.
What Influences Doctors’ Perceptions of The Doctor–Patient Relationship? — A National Cross-Sectional Study in China
Authors: Liu Shiyang , Hu Linlin , Wu Shichao , Liu Yuanli
Published: June 2020

Background: Tense doctor–patient relationships have become a great challenge for the Chinese government due to their high incidence rate and negative social impact. This study aimed at exploring the factors influencing doctors’ perceptions of the doctor–patient relationship.Methods: We conducted a national cross-sectional study in 136 tertiary grade-A hospitals in China. A total of 19,774 doctors reported their perceptions of the doctor–patient relationship over the last two years, as well as sociodemographic factors, work experience, and hospital security measures. A logistic-regression model was used to identify factors significantly associated with doctors’ perceptions of the doctor–patient relationship.Results: Doctors’ perceptions of the doctor–patient relationship were relatively negative. Region, hospital type, gender, age, and income influenced these perceptions. With regard to doctors' work experience, those with excessive workloads, those who had experienced medical disputes, and those who did not have enough communication time with patients tended to report more-negative perceptions of the doctor–patient relationship. In terms of hospital security measures, doctors working in hospitals with effective precautions, in-place security staff, and medical-liability insurance purchased for medical staff tended to report more-positive perceptions of this relationship.Conclusion: Doctors’ work experiences and hospital security measures both played essential roles in improving doctors' perceptions of the doctor–patient relationship. On the part of doctors, improving their communication skills and providing adequate communication were beneficial to their perceived relationships with patients. On the part of hospitals, reducing doctors’ workloads, preventing medical disputes, and increasing job security and organizational support are potential ways to improve doctors' perceptions of these relationships.Practice implications：This study provided evidence and advice for Chinese government, as well as Chinese hospitals, to improve doctors’ perceptions of the doctor-patient relationship by measures of enhancing doctors’ work experiences and hospital security.
Earthquake Magnitude Prediction using Probabilistic Classifiers
Authors: Fahandezhsadi Mahshid , Sadi Hamed Fahandezh
Published: June 2020

Background: Earthquake prediction plays an important role in preventing catastrophic damage. We present here a scheme for earthquake prediction using an improved version Tree Augmented Naïve Bayes (TAN). This approach can achieve an appropriate performance by extracting dependencies among seismicity features effectively. At first we use the simplest Discretization Method, Equal Interval Width, for discretization of six seismicity features (Time, Mean Magnitude, Energy, Slope, deviation, Magnitude deficit) drive from National Earthquake Information Center (NEIC), then in order to the magnitude of earthquake we utilize an improve version of Tree Augmented Naïve Bayes that is based on Decomposable Models. Results: Finally, we test our method by using two schemes and compare it to Tree Augmented Naïve Bayes and Hidden naive Bayes classifier. F-measure metric is used for evaluation of our results. Conclusion: Experimental results demonstrated proposed approach based on an improved version of Tree Augmented Naïve Bayes achieves a higher performance compared to two other methods.
Identification and Characterization of Metastasis-Associated Individualized Gene Expression Signature in Osteosarcoma
Authors: Zhang Guofeng , Zhu Yonglin , Jin Chengzhen , Zhou Baisui , Zhao Shanrun , Li Chuanbo , Fu Fangang , Li Shanhui
Published: June 2020

Background: Osteosarcoma (OS) patients with surgical resection still relapse with poor prognosis due to the inability to detect distant metastasis. It’s essential to identify metastasis-related biomarkers for OS. Methods: Here, a computational pipeline follow relative expression orderings (REOs) using gene expression was constructed in metastases and non-metastases OS patients. Results: 138 metastasis-associated gene pair signatures (MGPSs) were identified follow two independent datasets. A metastases-specific co-expressed MGPS network was constructed for extracting biomarker for clinical application. MGPS such as MYL5 and RPL27A showed strong positive correlation (Cor =0.75, P <0.001). There were thirteen prognostic MGPSs in above network. These prognostic MGPSs could become as a specific classifier to distinguish metastases and non-metastases OS patients. MGPSs were associated with cancer metastasis-related functions. Drug and MGPS network could provide some drug candidates for treatment of OS. Conclusions: Collectively, the roles of the MGPSs in OS were elucidated, which could be beneficial for understanding OS pathogenesis and treatment.
Safe Behaviour in The Petrochemical Industry: Evaluating The Consistency Between Conceptual Frameworks and Factors Reported by Iranian Workers
Authors: Harsini Azita Zahiri , Bohle Philip , Matthews Lynda R , Ghofranipour Fazlollah , Sanaeinasab Hormoz , Shokravi Farkhondeh Amin , Prasad Krishan
Published: June 2020

Background: Unsafe worker behaviour is often identified as a major cause of dangerous incidents in the petrochemical industry. Behavioural safety models provide frameworks that may help to prevent such incidents by identifying factors promoting safe or unsafe behaviour. A literature review was conducted to identify models of safe behaviour and determine which were most consistent with the experiences reported by workers in our qualitative study of the Iranian petrochemical industry.Methods: Five databases (EBSCOhost, Google Scholar, ProQuest, Science Direct, Scopus) were searched for studies between 2000 and 2019 that evaluated antecedents and outcomes of safe workplace behaviours in the petrochemical industry or other industrial settings. After duplications were removed, 141 publications were screened and 31 that met the inclusion criteria were reviewed. Constructs described in each publication were assessed for consistency with themes derived from the interview responses from Iranian petrochemical workers in the qualitative study: poor direct safety management and supervision; unsafe workplace conditions; workers' perceptions, skills and training; and broader organisational factors. Results: The themes identified in the qualitative study most closely matched those in the model described by Wu et al. (2011): poor direct safety management and supervision matched with safety leadership and several subscales; unsafe workplace conditions matched with several subscales; workers' perceptions, skills and training matched with two subscales, and broader organisational factors matched with two other subscales. The model selected was the one that included the most constructs matching the themes identified in the qualitative study.Conclusions: Valid behavioural safety models can provide a basis for more effective safety cultures and management systems in selected contexts. This study identified most consistency between themes elicited from Iranian petrochemical workers and the constructs described by Wu et al. (2011), providing evidence of the validity of their model. Intervention studies are needed to assess the effectiveness of safety models in improving safe behaviours in industrial settings.Trial registration: Iranian Registry of Clinical Trials: IRCT20170515033981N2. Registered 19 June 2018. https://www.irct.ir/trial/26107
Association Between Alcohol use in Pregnancy and Preeclampsia or Hypertension in Pregnancy: A Systematic Review
Authors: Gong Weiyan , Zeng Na , Corsi Daniel , Wen Shi Wu
Published: June 2020

BackgroundTo summarize evidence on the association of maternal alcohol consumption during pregnancy with preeclampsia (PE) or hypertensive disorders of pregnancy (HDP).Methods We searched PubMed, EMBASE, PsycINFO, and Cochrane Central Register of Controlled Trials databases. We included original studies that presented relative risks, odds ratios, or data to calculate the risks for the association of alcohol consumption during pregnancy with PE or HDP. We used the Newcastle-Ottawa Scale to assess study quality. We conducted a random-effects meta-analysis to calculate the pooled association of gestational alcohol use with PE or HDP.ResultsThirty-seven articles met the criteria for inclusion. The total study population was 4,434,003 women with 170,481 cases of PE and 467,055 women with 41,708 cases of HDP. For all included studies, there was no significant association between alcohol consumption during pregnancy and incidence of PE (OR=0.93, 95%CI: 0.73-1.20), with statistical significant heterogeneity (I2=91%, P<0.00001). Among the subgroup of prospective cohort studies, the pooled results showed that alcohol consumption during pregnancy had a protective effect on PE (OR=0.64, 95% CI: 0.54-0.76), and with no statistical heterogeneity (I2 =0%, P=0.56). The results from the subgroup of retrospective cohort and case-control studies showed that alcohol consumption during pregnancy was not associated with PE, with odds ratios of 1.07 (0.65-1.74) and 1.02 (0.64-1.61), respectively, and with statistically significant heterogeneity. The pooled OR for the association between alcohol consumption during pregnancy and HDP was 0.98 (95% CI: 0.75-1.29), with considerable heterogeneity (I2=90% P<0.00001).ConclusionOverall, there is no apparent association of alcohol consumption during pregnancy with PE or HDP. In prospective cohort studies, an evident protective effect is likely due to residual confounding. Further studies should consider alternative designs such as mendelian randomization, which can overcome some of the limitations of conventional prospective studies.
Metabolic and Inflammatory Profile in Patients with COPD
Authors: Fekete Monika , Szollosi Gergo , Tarantini Stefano , Nemeth Anna N , Bodola Csenge , Varga Luca , Varga Janos Tamas
Published: June 2020

Background: In COPD, aside from obesity, decreased physical activity significantly increases the probability of developing metabolic syndrome, which can have a great impact on the natural course of COPD. Objective: The purpose of our study was to evaluate the prevalence of metabolic syndrome and whether it is related to age, sex, comorbidities, drug intake, degree of impairment of lung function, nutritional status, physical activity and quality of life. Methods: A cross-sectional study was performed on patients in Budapest at the Department of Pulmonary Rehabilitation of the National Koranyi Institute of Pulmonology between March 1, 2019 and March 1, 2020. The anthropometric and respiratory function tests and laboratory parameters of a random sample of 401 patients were known. Metabolic syndrome was determined according to IDF criteria and by definition CRP levels above 5.0 mg/L were considered elevated. Results: Metabolic syndrome occurred in 59.1% of COPD patients, male: 49.7% female: 67.6% (p <0.001). Patients with metabolic syndrome had worse FEV1%pred (43 (30-56) vs. 47 (36-61); p=0.028), lower 6MWD (250 (150-330) vs. 277 (162-360); p=0.235), lower quality of life, and significantly higher number of exacerbations (3 (1-6) vs.1 (0-3); p <0.001), than patients without metabolic syndrome. C-Reactive protein level was elevated in 55.1% of patients, higher in patients with metabolic syndrome, but the difference was not significant (7.0 (2-18) vs. 5.1 (1-17); p = 0.064). Conclusions: MetS can affect respiratory function, physical activity, quality of life and the number of exacerbations and is related to nutritional status and the level of systemic inflammation.
Multi-omics Prognostic Analysis of Lysine Acetylation Regulators in Glioma
Authors: Tu Zewei , Lv Shigang , Wu Lei , Hu Qing , Tao Chuming , Li Kuangxun , Zhu Xingen , Huang Kai
Published: June 2020

Background: Lysine acetylation is a crucial kind of protein modification and is related to the malignant development of various cancers. But their roles in glioma are still unclear and needed concluded comprehensively. Methods: In this study, we comprehensively analyzed the expression levels of 33 lysine acetylation regulators (LARs) and prognostic roles by using public data, including the Chinese Glioma Genome Atlas (CGGA) and The Cancer Genome Atlas (TCGA). The prognostic roles of LARs were judged by univariate Cox regression. Consensus clustering was applied to result in three stratified glioma subtypes (LA1, 2, and 3) with different clinical outcomes. We also constructed a risk signature for predicting the overall survival of glioma patients by using least absolute shrinkage and selection operator regression (LASSO regression). Besides, copy number variations (CNVs) and single nucleotide polymorphism (SNP) of LARs were also analyzed in our study. Results: We found the mRNA expression levels of most of LARs were dysregulated in gliomas and associated with the prognosis of glioma patients. The risk signature constructed by 14 LARs presented an independent prognostic role in both the CGGA (HR:1.96, 95%CI:1.33-2.90) and TCGA (HR:1.48, 95%CI:1.08-2.03) datasets and robust predictive effects in the ROC curves with all of area under curves more than 0.800. Moreover, the copy number variations of LARs were also significantly related to the prognosis of glioma patients, in which HDAC1 (1p) was one of the oncogenes lost in 1p/19q codeletion events, while SIRT2 (19q) and EP300 (22q) may act as tumor suppressors in gliomas with 19q or 22q deletions, respectively. Conclusion: LARs are potential biomarkers for the malignant progression of gliomas, and our results could be useful for predicting the OS of glioma patients and provide some clues in searching the functions of LARs in glioma progression. Keywords: glioma, lysine acetylation regulator, epigenetic, prognostic signature, biomarker.
Identification and the First Record of Marine bacteria Mudskippers Boleophthalmus dussumieri (Valenciennes, 1837) by 16S rRNA on the Northern Intertidal areas of Persian Gulf, Iran
Authors: nassirabady nerssy , Ghotbeddin N. Negar , Roomiani Laleh
Published: June 2020

Background

Mudskipper is from the Gobiidae family and from the subfamily Oxudercinae. Mudskipper contains four main genera Boleophthalmus, Periophthalmodon, Periophthalmus, and Scartelaos. The aim of this research identification of bacterial agent (Marine bacteria) mudskippers Boleophthalmus dussumieri on the Shores of the northern intertidal areas of the Persian Gulf (Abadan, Hendijan and Bahrekan), Iran. The mud sediment and water samples (at the depth of one m), and mudskipper fish samples (near shore at the intertidal) were collected from Abadan, Hendijan and Bahrekan in northern coasts of the Persian Gulf, Iran.
Results

A total of 80 aerobic bacteria marine (from the intestines of mudskipper, seawater, and muddy sediments ) was identified by biochemical tests and 16S rRNA gene sequence analysis. The bacteria's (Marine bacteria) [Eubacterium] tenue strain DSM 20695, Praclostridium bifermentans strain JCM 1386 and Vibrio hyugaensis strain 090810a was first identified in the northern intertidal areas of Persian Gulf, Iran.
Conclusions

Bacteria compete with other organisms to get oxygen to the surface layers of the flower bed. They give that the bacterial species common to the fish intestines and sediments is high and due to fish feeding of sediment it can be concluded that the species present in the fish intestine in the present study may be a function of substrate species that needs further studies to prove this.
Microscopic extra-laminar sequestrectomy (MELS) for the treatment of hidden zone lumbar disc herniation: report of the surgical technique, patient selection, and clinical outcomes
Authors: Wang Chunxiao , Zhang Yao , Tang Xiaojie , Cao Haifei , Song Qinyong , Tan Jiangwei , Jin Chengzhen , Song Hongkai
Published: June 2020

Background

Surgical management of lumbar disc herniation in the hidden zone is technically challenging due to its difficult surgical exposure. The conventional interlaminar approach harbors the potential risk of post-surgical instability, while other approaches consist of complicated procedures with a steep learning curve and prolonged operation time.
Objective

To introduce a safe and effective technique named microscopic extra-laminar sequestrectomy (MELS) for treatment of hidden zone lumbar disc herniation and present clinical outcomes within a two year follow-up period.
Methods

Between Jan 2016 to Jan 2018, twenty one patients (13 males) with hidden zone lumbar disc herniation were enrolled in this study. All patients underwent MELS (19 patients underwent sequestrectomy only, 2 patients underwent an additional inferior discectomy). The nerve root and herniated fragment were visually exposed using this extra-laminar approach. The operation duration, blood loss, intra- and postoperative complications, and recurrences were recorded. The Visual Analog Scale (VAS), Oswestry Disability Index (ODI), and the modified MacNab criteria were used to evaluate clinical outcomes. Postoperative stability was evaluated both radiologically and clinically.
Results

The mean follow-up period was 20.95 ± 2.09 months, ranging from 18 to 24 months. The mean operation time was 32.43 ± 7.19 min and the mean blood loss was 25.52 ± 5.37 ml. All patients showed complete neurological symptom relief after surgery. The VAS and ODI score were significantly improved at the final follow-up compared to those before operation (7.88 ± 0.70 vs 0.10 ± 0.30, 59.24 ± 10.83 vs 11.29 ± 3.59, respectively, p < 0.05). Seventeen patients (81%) obtained an “excellent” outcome and the remaining four (19%) patients obtained a “good” outcome based the MacNab criteria. One patient suffered reherniation at the same level one year after the initial surgery and underwent a transforaminal endoscopic discectomy. No major complications and postoperative instability were observed.
Conclusions

Our observation suggest that MELS is a safe and effective method in the management of hidden zone lumbar disc herniation. Due to its relative simplicity, it comprises a flat surgical learning curve and shorter operation duration, and overall results in reduced disturbance to lumbar stability.
ABBV-744 and Onalespid as Potential Inhibitors of SARS-CoV-2 main Protease Enzyme: A Promising Therapeutics in COVID-19?
Authors: Fakhar Zeynab , Khan Shama , Ahmad Aijaz
Published: June 2020

A new pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide and become pandemic with thousands new deaths and infected cases globally. To address coronavirus disease (COVID-19), currently no effective drug or vaccine is available. This necessity motivated us to explore potential lead compounds by considering drug repurposing approach targeting main protease (Mpro) enzyme of SARS-CoV-2. This enzyme considered to be an attractive drug target as it contributes significantly in mediating viral replication and transcription. Herein, comprehensive computational investigations were performed to identify potential inhibitors of SARS-CoV-2 Mpro enzyme. The structure-based pharmacophore modeling was developed based on the co-crystallized structure of the enzyme with its biological active inhibitor. The generated hypotheses were applied for virtual screening based PhaseScore. Docking based virtual screening work-flow was used to generate hit compounds using HTVS, SP and XP based Glide GScore. The pharmacological and physicochemical properties of the best hit compounds were characterized using ADMET. Molecular dynamics simulations were performed to explore the binding affinities of the considered compounds. Binding studies revealed that compound ABBV-744 binds to the Mpro with strong affinity (Gbind -45.43 kcal/mol), and the complex is more stable in comparison with other protein-ligand complexes. Our study classified three best compounds which could be considered as promising inhibitors against main protease SARS-CoV-2 virus.