bluuebunny/crossref_metadata_2025 huggingface dataset:
Ascomycota In the Shallow Ecoregion of Catarina, Caatinga, Brazil: Part 1
Authors: Vitória Nadja Santos , Silva Mabel Sherlla Rozendo Campos da , Santos Maiara Araújo Lima dos , Cáceres Marcela Eugenia da Silva , Aptroot André , Bezerra José Luiz
Published: April 2024

Objective: Inventories of fungi are essential, but they are rarely carried out, especially in areas of the Caatinga biome. It is therefore important to carry out surveys and mapping to make knowledge more accessible.  In this context, the aim of this work was to organize and discuss the information and data related to the fungi of Raso da Catarina, cataloguing and presenting the first checklist of Ascomycota in an insufficiently researched locality, adding knowledge from scientific collections, publications, and field expeditions.
 
Method: Literature searches were carried out on the Ascomycota of the Raso da Catarina Ecoregion; consultations of the Fungal Databases, U.S. National Fungus Collections, the EMBRAPA database (Fungi Reported on Plants in Brazil) and the Mycology Collections Portal; consultations of the speciesLink networks that integrate data from scientific collections; consultations of the Reflora Virtual Herbarium and the INCT-Herbário Virtual da Flora e dos Fungos. In addition to field expeditions in areas of the Raso da Catarina in the municipalities of Paulo Afonso, Jeremoabo and Glória.
 
Results and conclusion: A total of 243 taxa comprising 75 asexual fungi, 85 lichenized sexual fungi and 73 non-lichenized sexual fungi, distributed in 148 genera, were catalogued. This work represents an initiative to systematize research carried out in Raso da Catarina, with the aim of adding knowledge to the estimate of Ascomycota species in the Caatinga.
 
Originality/value: Work on fungi in areas of the Raso da Catarina is still incipient. Some data is scattered in a few publications and many taxa are in scientific collections without being published. This is therefore the first checklist of Ascomycota for the Ecoregion and provides relevant information.
Public Service Policy in The Form of Civil Registration
Authors: Marewa Yeheschiel Bartin , Muttaqin Elfran Bima , Salim Agus
Published: April 2024

Purpose: to determine and analyze the implementation of public services at the Population Service and the obstacles to implementing public services at the Population and Civil Registration Service of North Toraja Regency.
 
Methode: juridical-normative sourced from primary and secondary materials which are analyzed qualitatively by describing descriptively the results of the relevant data and cases studied.
 
Research results: the implementation of public services in issuing population documents in North Toraja Regency has not been optimal, this can be seen in three things, including: population registration, civil registration and population document data. The public service process in issuing population documents has not been fully implemented by residents, the data exchange that occurs in population documents and the many procedures for public services in issuing population documents that are not implemented, and the obstacles to implementing public services at the Population and Civil Registration Service of North Toraja Regency , namely legal basis aspects, institutional aspects, human resource (HR) constraints, lack of budget, and low public awareness, as well as lack of socialization regarding government regulations.
 
Research implications: Public services in civil registration make it easier for the government to register every citizen in an orderly and orderly manner, increasing the recruitment of competent and proportional resources will support good and sustainable services.
 
Originality/value: In the above context, the government is expected to prioritize effective services and recruit competent employees in the field of public services.
The effect of Lignova sorbent to the concentration of interleukin-6 in the blood and bile in patients with mechanical jaundice of tumors etiology
Authors: Aripova N. U. , Ismailov U. S. , Baymakov S. R. , Adilkhodjaev A. A. , Pulatov M. M. , Matmuratov S. K. , Jamalov S. I. , Yunusov S. Sh.
Published: April 2024

The OBJECTIVE was to study changes of IL-6 concentration in the blood and bile in patients with MJ of tumor genesis by means of biliary sorption.

METHODS AND MATERIALS. The investigation was conducted to study changes in the concentration of IL-6 in the blood and bile against the background of bile sorption in 105 patients with mechanical jaundice (MJ), the cause of obturation was a tumor of the periampullary zone. The patients are divided into two groups. The first group consisted of 51 patients, the second group included 54 patients. All patients of the main group underwent percutaneous perhepatic cholangiostomy for the purpose of decompression; bile sorption was performed using the domestic Lignov enterosorbent. The level of IL-6 in blood serum and bile was determined by enzyme immunoassay.

RESULTS. The use of bile sorption in the treatment complex significantly changed the concentration of IL-6 in blood serum (P<0.01) and bile. Determination of IL-6 in blood and bile makes it possible to more objectively assess the degree of cytokine-induced endogenous intoxication in response to ongoing therapeutic measures for tumors of the periampullary zone complicated by mechanical jaundice. The use of bile sorption contributes to a decrease in the concentration of the pro-inflammatory cytokine IL-6 in the blood and bile as an inducer of endogenous intoxication and a cascade of inflammatory processes in patients with tumors of the periampullary zone complicated by mechanical jaundice.

CONCLUSION. Bile sorption application helps to decrease proinflammatory cytokine IL-6 concentration in blood and bile as an inductor of endogenous intoxication and inflammatory processes cascade.
A case of surgical treatment of an aneurysm of the internal carotid artery with severe angulation
Authors: Kalinin R. E. , Suchkov I. A. , Pshennikov A. S. , Karpov V. V. , Egorov A. A. , Solianik N. A. , Afenov M. R.
Published: April 2024

The leading role among causes of CVA (cerebrovascular accident) is occupied by pathology of the internal carotid artery. The most common etiological factor is a pronounced atherosclerotic process in the area of carotid artery bifurcation. Significantly less common factors are non-atherosclerotic causes of internal carotid artery disease, which include aneurysm and pathological tortuosity. Their combination significantly increases the risk of cerebral events, which requires timely surgical treatment. Surgical treatment is associated with certain intraoperative difficulties. The following is a clinical case of surgical treatment of an aneurysm of the internal carotid artery extracranial segment in combination with its deformation correlated with hemodynamic stenosis of more than 70%. A resection of the tortuosity-aneurysm complex with the formation of an end-to-end anastomosis of the internal carotid artery was performed.
Simultaneous replacement of the aortic valve and hip joint in a patient with critical aortic stenosis and femoral neck fracture
Authors: Petrov S. V. , Peleshok A. S. , Ignatenko V. L. , Mutalibov O. M. , Krivopalov V. A. , Khubulava G. G. , Pilyugov N. G.
Published: April 2024

Concomitant cardiovascular diseases in elderly patients with a hip fracture significantly increase the risk of developing postoperative complications. Developing the treatment algorithm for a combination of two or more diseases in this category of patients is the main task. The advantages of simultaneous surgery are one-stage repair of two or more surgical diseases, the implementation of one anesthetic procedure, the reduction in the total time of the patient’s stay in the hospital and the reduction in rehabilitation time. This paper presents the clinical observation of simultaneous surgical treatment of severe aortic stenosis and femoral neck fracture in an elderly patient.
Commentary on the article by S. V. Petrov et al. «Simultaneous replacement of the aortic valve and hip joint in a patient with critical aortic stenosis and femoral neck fracture»
Authors: Polushin Yu. S.
Published: April 2024

.
Academician Yuri Fedorovich Isakov (1923–2016) (on the 100th anniversary of his birth)
Authors: Kurygin Al. A. , Semenov V. V. , Dovganyuk V. S.
Published: April 2024

Outstanding pediatric surgeon, scientist, teacher and health care organizer, founder of a large school of pediatric surgeons, Honored Scientist of the RSFSR (1973), academician of the USSR Academy of Medical Sciences (1975) and the Russian Academy of Sciences (2013), vice-president of the Russian Academy of Medical Sciences (1989–2001), laureate of two State USSR Prizes (1979, 1985) and the State Prize of the Russian Federation (1999), Chief Pediatric Surgeon of the USSR Ministry of Health (1966–1981) and the Russian Ministry of Health (1992–2005), Deputy Minister of Health of the USSR (1981–1987), Professor Yuri Fedorovich Isakov was born on June28, 1923 in Kovrov, Vladimir region. In 1966, he was elected head of the department of surgical diseases of childhood at the 2nd Moscow Medical Institute named after N. I. Pirogov and led it for 40 years. The surgical and scientific activities of Yuri Fedorovich were distinguished by a very wide range of areas. On the problems of thoracic surgery, extensive experience has been accumulated in the treatment of children with diseases and malformations of the neck, chest, lungs, mediastinum, and esophagus. Many diverse research works have been carried out on topical issues of abdominal surgery. Yu. F. Isakov made a very large contribution to the development of endovideosurgery in children. The clinic became one of the first in the country to create a specialized endovideosurgical service. Under the leadership of Yuri Fedorovich and with his direct participation, pediatric nephrurology and vascular surgery quickly developed, scientific research was conducted on topical issues of combined trauma of the musculoskeletal system, an anesthesiology, resuscitation and intensive care service was organized in the clinic, fundamental research was carried out on the problem of pain management in children surgery. Yu. F. Isakov was the author and co-author of more than 500 scientific works, including 23 monographs and manuals, 7 textbooks and teaching aids. At the department headed by Yuri Fedorovich, 390 dissertations were defended, including 67 doctoral dissertations. Academician Yuri Fedorovich Isakov died on August 4, 2016 and was buried at the Troekurovskoye cemetery in Moscow.
Local negative pressure technique in abdominal surgery: advantages, disadvantages, controversial issues
Authors: Sazonov A. A. , Romashchenko P. N. , Makarov I. A. , Aliev R. K. , Maistrenko N. A.
Published: April 2024

A literature review of studies on the use of local negative pressure technique (vacuum therapy) in abdominal surgery is presented. The article highlights modern approaches to its use in emergency pathology of the abdominal cavity and retroperitoneal space. The mechanisms of action, advantages and disadvantages of the local negative pressure technique, as well as the main morphofunctional aspects of its application are discussed in detail. Data from recent clinical studies and meta-analyses are summarized, and the effectiveness of using vacuum-assisted laparostomy within the framework of the «damage control» concept in multi-stage surgical treatment of injuries and urgent abdominal diseases accompanied by abdominal sepsis is demonstrated. The use of local negative pressure techniques can reduce postoperative mortality, as well as shorten the length of hospital treatment of patients. However, despite the obvious positive effect on the course of the wound process, vacuum therapy carries the risk of developing serious complications, the most dangerous of which are bleeding and perforation of hollow organs. In addition, it requires very expensive equipment and consumables, as well as training of medical personnel. Thus, the use of vacuum therapy requires a sound approach and a clear understanding of the technical features of its implementation. However, the indications for the use of local negative pressure in abdominal surgery have not yet been clarified, which undoubtedly hinders the wider introduction of this promising technique into clinical practice.
Indigenous languages and the field of linguistics
Authors: Oxford Will
Published: April 2024

Indigenous languages play a prominent role in the academic discipline of linguistics, particularly in Canada. Linguists have worked extensively with speakers of Indigenous languages in the documentation and analysis of vocabulary, grammar, and discourse. Such work can have beneficial outcomes for both the field of linguistics and the communities in which Indigenous languages are spoken. However, it cannot be denied that the field of linguistics has often enjoyed a disproportionate share of these benefits. This brief article outlines the goals of modern linguistics, the role that Indigenous languages have played in the field, and the tensions that can exist between the different priorities of academic linguists and Indigenous communities.
Creating the booklet Indigenous Languages in Canada
Authors: Gold Elaine
Published: April 2024

The creation of the booklet Indigenous Languages in Canada was initiated by the Canadian Language Museum (CLM) and brought to fruition through the generous support of the Robarts Centre for Canadian Studies. The CLM undertook this project because we believe that it is very important to raise awareness of the rich diversity of Indigenous languages in Canada.
The Genetics behind Sulfation: Impact on Airway Remodeling
Authors:   Laboratory of Pharmacology, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece, Ntenti Charikleia , Papakonstantinou Eleni ,   Clinic of Respiratory Medicine, Faculty of Medicine, University of Freiburg, Freiburg, Germany, Fidani Liana ,   Laboratory of Medical Biology-Genetics, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece, Stolz Daiana ,   Clinic of Respiratory Medicine, Faculty of Medicine, University of Freiburg, Freiburg, Germany, Goulas Antonis ,   Laboratory of Pharmacology, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece
Published: April 2024

In COPD, chronic inflammation, and exposure to irritants, such as cigarette smoke, leads to the thickening of bronchial walls. This results from increased deposition of collagen and other extracellular matrix components, contributing to the narrowing of airways. Nevertheless, it is widely recognized that COPD is an inflammatory disorder marked by partially reversible airflow limitation wherein genetic factors interact with the environment. In recent years, numerous investigations have substantiated the correlation between gene polymorphisms and COPD. SUMF1 has been implicated in diverse cellular processes, including lysosomal function and extracellular matrix maintenance, both of which play pivotal roles in respiratory health. The genetic variations in SUMF1 could lead to an imbalanced sulfation in the extracellular matrix of lung tissue, potentially playing a role in the onset of COPD. Recent studies have uncovered a potential link between dysregulation of SUMF1 and COPD progression, shedding light on its involvement in the abnormal sulfatase activity observed in COPD patients. Through a comprehensive review of current literature and experimental findings, this article aims to contribute to the growing body of knowledge surrounding the genetic intricacies concerning sulfation, of airway remodeling and possible pharmacological applications in COPD and asthma management.
Fenugreek (Trigonella Foenum-Graecum L.): Health, Medicine and Chemistry
Authors:   Laboratory of Plant Biotechnology and Molecular Biology, Department of Biology, Faculty of Sciences, University Moulay Ismail, PO. Box 11201, Zitoune, Meknes, Morocco, Rahal El Kahkahi , Meryama Moustaine ,   Laboratory of Botany and Plant Protection, Faculty of Sciences, University Ibn Tofail, BP 133, University Campus, Kenitra, Morocco, Rachid Zouhair ,   Laboratory of Plant Biotechnology and Molecular Biology, Department of Biology, Faculty of Sciences, University Moulay Ismail, PO. Box 11201, Zitoune, Meknes, Morocco
Published: April 2024

Fenugreek (Trigonella foenum-graecum L.), is widely destributed throughout the world and belongs to the Fabacecae family. It is an old medicinal plant and has been commonly used as a traditional food and medecine. Fenugreek is known to have hypoglycemic, and hypocholesterolaemic effects. Recent research has identified fenugreek as a valuable medicinal plant with potential for multipurpose uses and also as a source for preparing raw materials of pharmaceutical industry, especially steroidal hormones. This review article summarizes and reviews puplished experimental studies and scientific literature from the databases including PubMed, Google, Scpous and Local library.
Transcending Lifshitz Theory: Reliable Prediction of Adhesion Forces between Hydrocarbon Surfaces in Condensed Phases using Molecular Contact Thermodynamics
Authors: Siles-Brugge Oscar , Hunter Christopher , Leggett Graham
Published: April 2024

Works of adhesion W(Lifshitz) between hydrocarbon surfaces in 260 liquids were calculated using Lifshitz theory and compared with interaction free energies ∆∆G determined using a model in which the interactions between a molecule and a liquid are described by a set of surface site interaction points (SSIP). The predictions of these models diverge in significant ways. Interaction free energies calculated using the SSIP approach are typically small and vary little, but in contrast, Lifshitz theory yields works of adhesion that span a broad range. Moreover, the SSIP model also yields significantly different ∆∆G values in some liquids for which, in contrast, Lifshitz theory predicts similar values of W. These divergent predictions were tested using atomic force microscopy. The experimentally determined work of adhesion was found to be closer to the value predicted using the SSIP model than to W(Lifshitz). Still greater differences were found in the interaction energies calculated using the two models when liquid mixtures were considered. For mixtures of methanol and benzyl alcohol, ∆∆G declines smoothly as the benzyl alcohol concentration increases, but W(Lifshitz) decreases to a minimum and then increases, reaching a larger value for benzyl alcohol than for methanol. The experimental adhesion data were correlated closely with the predictions of the SSIP model. We conclude that the molecular-scale treatment intrinsic to the SSIP approach enables adhesive interactions to be modelled more accurately than is possible using Lifshitz theory, which instead uses the bulk properties of the medium to predict work of adhesion values.
Development of Peptoid-Based Heteroaryl-Decorated Histone Deacetylase (HDAC) Inhibitors with Dual-Stage Antiplasmodial Activity
Authors: Stopper Daniel , de Carvalho Lais Pessanha , de Souza Mariana Laureano , Winzeler Elizabeth , Held Jana , Hansen Finn Kristian
Published: April 2024

Malaria remains a significant global health challenge, causing approximately 608,000 deaths and over 249 million infections in 2022. With the rise of resistance to current chemotherapies, including artemisinin-based combination therapies (ACTs), the search for novel antimalarial drugs with new modes of action is of utmost importance. Histone deacetylases (HDACs) have been identified as promising targets for antiplasmodial drug development. In this study, we present a novel series of peptoid-based HDAC inhibitors incorporating heteroaryl residues, synthesized via an efficient multicomponent protocol. The subsequent screening of 16 compounds from our mini-library identified 6i as the most promising candidate, demonstrating potent activity against asexual blood-stage parasites (IC50 Pf3D7 = 30 nM; IC50 PfDd2 = 98 nM), low submicromolar activity against liver-stage parasites (IC50 PbEEF = 0.25 µM), excellent microsomal stability (t1/2 > 60 min), and negligible cytotoxicity to HepG2 cells (IC50 > 10 µM).
Synthesis, characterization and stability of phosphonium phenolate zwitterions derived from a (diphenylphosphino)phenol derivative and oxiranes
Authors: Steiner Matthias , Marschner Christoph , Baumgartner Judith , Hlina Johann , Slugovc Christian
Published: April 2024

Phosphonium phenolate zwitterions have been synthesized from 2,4-di-tert-butyl-6-(diphenylphosphino)phenol and five different oxirane derivatives. The reaction does not proceed at a detectable rate when the two reactants are combined in dichloromethane at room temperature. Despite the substantial ring strain, the reaction proceeds only with the addition of methanol, which acts as a hydrogen transfer shuttle, allowing a slow conversion to the desired zwitterions. The compounds have been fully characterized and single crystal X-ray crystallography has been performed on the methyloxirane and the phenyl glycidyl ether-derived zwitterion. The phosphonium phenolate units exhibit an ylidic bonding situation as evidenced by spectroscopic and crystallographic analysis. Glycidyl ethers were found to react faster than alkyl and aryloxiranes. Decomposition studies of the zwitterions showed high thermal stability in solution under ambient conditions. Under forced conditions (150 °C, 6 h), decomposition to the corresponding phosphine oxide and secondary aliphatic alcohols, the formally hydrogenated oxirane derivative, was observed.
Self-Diffusion of Acetonitrile in a Covalent Organic Framework: Simulation and Experiment
Authors: Grunenberg Lars , Keßler Christopher , Teh Tiong Wei , Schuldt Robin , Heck Fabian , Kästner Johannes , Groß Joachim , Hansen Niels , Lotsch Bettina V.
Published: April 2024

Covalent Organic Frameworks have emerged as a new class of porous materials whose sorption properties have so far been studied primarily with physisorption techniques. Quantifying the self-diffusion of guest molecules in the interior of their nanometer-sized pores allows for a better understanding of confinement effects or transport limitations and is thus vital for various applications ranging from molecular separation to catalysis. Using a combination of pulsed field gradient nuclear magnetic resonance (PFG NMR) measurements and molecular dynamics (MD) simulations we have probed the self-diffusion of acetonitrile in the 1.7 nm diameter pore channels of two imine-linked COFs (PI-3-COF) featuring different levels of crystallinity and porosity, between 270 K and 300 K. In the sample showing higher crystallinity and porosity, we observe clear evidence for anisotropic diffusion parallel to the pore channel direction as characterized by a diffusion coefficient of D_par = 6.1 × 10^-10 m2/s at T = 300 K, consistent with 1D transport. Self-diffusion in the pores vs. bulk liquid is thus reduced by a factor of 7.4, in good agreement with MD simulations which predict a reduction of the self-diffusion coefficient by a factor of 5.4 compared to the bulk liquid value, assuming an offset-stacked COF layer arrangement. In contrast, more frequent diffusion barriers give rise to isotropic, yet significantly reduced diffusivities in the low-porosity sample (D_B = 1.4 × 10^-11 m2/s at T = 300 K). Our multimodal study thus highlights the significant influence of real structure effects such as stacking faults and grain boundaries on the long-range diffusivity of molecular guest species, while suggesting efficient intracrystalline transport at short diffusion times.
Ligand Tail Controls Shape Shifting of Indium Sulfide Ultrathin Nanoribbons
Authors: Guillemeney Lilian , Dutta Sarit , Mahler Benoit , Patriarche Gilles , ABECASSIS Benjamin
Published: April 2024

We report the conformational control of 2D ultra-thin indium sulfide nanoribbons by tuning their amine ligands' alkyl chain. The initial orthorhombic InS nanoribbons bare octylamine ligands and display a highly curved geometry with a characteristic figure of eight shapes. Exchanging the native ligand by oleylamine induces their complete unfolding to yield flat board-shaped nanoribbons. Significant strain variations in the InS crystal structure accompany this shape-shifting. By tuning the linear alkyl chain length from 4 to 18 carbon atoms, we show using SAXS in solution and TEM that the curvature of the nanoribbon subtly depends on the ligand-ligand interactions at the nanoribbon's surface. The curvature decreases gradually as the chain length increases, while carbon unsaturation has an unexpectedly significant effect at constant chain length. These experiments shed light on the critical role of the ligand monolayer on the curvature of ultrathin 2D crystalline nanosheets and demonstrate that weak supramolecular forces within the organic part of colloidal nanocrystals can dramatically impact their shape. This transduction mechanism, in which changes in the organic monolayer impact the shape of a nanocrystal, will help devise new strategies to design stimuli-responsive systems that take advantage of both the flexibility of organic moieties and the physical properties of the inorganic core.
Characteristics of NaNbO3 templates and improvement of electrical properties of textured KNLNS-BNKT ceramics
Authors: Vuong Le Dai
Published: April 2024

In this study, plate-like perovskite NaNbO3 (NN) templates were formed from Bi2.5Na3.5Nb5O18 (BiNN5) precursors via a molten salt method. The structure and microstructure of BiNN5 precursors and NN templates were studied. As a result, the platelike BiNN5 precursor particles have a bismuth layer perovskite structure, which is the basis for forming the synthesized plate-like NN particles that have a high aspect ratio with a width of 2-7 μm, a length of 5-12 μm and a thickness of 0.5-1 μm. From NN templates, we fabricated textured lead-free 0.98(K0.48Na0.48Li0.04)(Nb0.95Sb0.05)O3 − 0.02Bi0.5(Na0.4K0.1)TiO3 (KNLNS- BNKT) ceramic by the grain orientation technique. Experimental results show that the KNLNS-BNKT ceramics have a single-phase orthorhombic structure in which textured KNLNS-BNKT ceramics with 67% grain orientation. The electrical properties of the oriented ceramic are significantly improved compared to the non-oriented ceramic fabricated by the traditional method. Specifically, the electrical properties of the resulting KNLNS-BNKT oriented ceramics have a high dielectric constant (ε = 1323, an increase of 17%); large remnant polarization (Pr = 13.5 mC/cm2, an increase of 11.9%); high piezoelectric coefficient (d33 = 205 pC/N, an increase of 32%) and high electromechanical coupling coefficient (kp = 0.4, an increase of 11%).
MỘT HƯỚNG TIẾP CẬN LẬP LỊCH NHÓM TỐI ƯU TRONG MẠNG CHUYỂN MẠCH CHÙM QUANG
Authors: Nguyễn Hồng Quốc
Published: April 2024

Lập lịch là một trong những hoạt động quan trọng trong mạng chuyển mạch chùm quang. Khi gói điều khiển của một chùm đến tại một nút lõi mạng, dựa vào thông tin được chứa trong gói điều khiển như thời điểm đến, thời điểm kết thúc của chùm, một giải thuật lập lịch sẽ được gọi để tìm kênh bước sóng ra khả dụng cho việc lập lịch chùm đến. Mục đích chính của giải thuật lập lịch là sắp xếp các chùm đến trên các kênh bước sóng ra sao cho tối đa hiệu suất sử dụng băng thông và giảm mất mát chùm. Trong bài báo này chúng tôi đề xuất một giải thuật lập lịch nhóm MF_GS nhằm tối ưu kết quả lập lịch trong mỗi khe thời gian chờ lập lịch. Qua phân tích và đánh giá từ kết quả mô phỏng, giải thuật được đề xuất mới đã khẳng định được ưu điểm, đó là giảm xác suất mất gói tin và giảm độ phức tạp của giải thuật.
“COVID-19 Vaccination – A Missile in the War on the Pandemic”
Authors: Ranganath TS Dr.
Published: April 2024

None
A Situational Review of Comprehensive Infection Prevention and Control Guidelines Aimed at Preventing the Nosocomial Spread of COVID-19
Authors: Maria D’Souza Pearl , Prabhaker Ugargol Allen
Published: April 2024

The COVID-19 pandemic has affected the world drastically by disrupting normal routines in society and healthcare facilities are no exception. Irrespective of a nationrsquos socio-economic background healthcare facilities are facing issues with shortage of skilled health workforce personal protective equipment PPE lack of oxygen supplies and adherence to multiple changes in infection prevention and control practices. Coronavirus disease COVID-19 caused by the novel severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 is leading to greater challenges for infection prevention and control measures in healthcare settings. Since the transmission can occur through droplets fomites airborne routes and from individuals who are asymptomatic or from individuals in the incubation phase the likelihood of spread of infection among the health care workers where there is close contact with infected individuals makes it very challenging. With guidelines being continuously updated as knowledge rapidly evolves and measures being taken even as there is unprecedented demand on healthcare facilities the authors felt the need to review and draw inferences from the relevant guidelines provided by the World Health Organization WHO International Health Organisations and respective Health Ministries which might serve to refresh and bring about better awareness among the health care workers and patients on tackling the nosocomial spread of COVID-19 and also highlight how the response to COVID-19 can in general help improve infection control practices and prevent nosocomial infection spread in healthcare settings in subsequent waves.nbsp
Structural basis of translation inhibition by a valine tRNA-derived fragment
Authors: Wu Yun , Ni Meng-Ting , Wang Ying-Hui , Wang Chen , Hou Hai , Zhang Xing , Zhou Jie
Published: April 2024

Translational regulation by non-coding RNAs is a mechanism commonly used by cells to fine-tune gene expression. A fragment derived from an archaeal valine tRNA (Val-tRF) has been previously identified to bind the small subunit of the ribosome and inhibit translation inHaloferax volcanii. Here, we present three cryo-electron microscopy structures of Val-tRF bound to the small subunit ofSulfolobus acidocaldariusribosomes at resolutions between 4.02 and 4.53 Å. Within these complexes, Val-tRF was observed to bind to conserved RNA-interacting sites, including the ribosomal decoding center. The binding of Val-tRF destabilizes helices h24, h44, and h45 and the anti-Shine–Dalgarno sequence of 16S rRNA. The binding position of this molecule partially overlaps with the translation initiation factor aIF1A and occludes the mRNA P-site codon. Moreover, we found that the binding of Val-tRF is associated with steric hindrance of the H69 base of 23S rRNA in the large ribosome subunit, thereby preventing 70S assembly. Our data exemplify how tRNA-derived fragments bind to ribosomes and provide new insights into the mechanisms underlying translation inhibition by Val-tRFs.
Pumice as a coarse aggregate substitute for lightweight concrete: Strength and density assessment
Authors: M. Shaju Pragash
Published: April 2024

This paper investigates the feasibility of using pumice as a substitute for coarse aggregate in lightweight concrete, focusing on its strength and density characteristics. A significant drawback of conventional concrete lies in its substantial dead load, rendering it economically inefficient as a structural material due to its high self-weight. Lightweight concrete, characterized by a lower density, addresses this concern by reducing dead loads and enhancing thermal insulation. This research focuses on achieving density reduction by partially replacing coarse aggregate with pumice in concrete of grade M20. The study aims to assess the structural viability of lightweight pumice concrete by determining its cube compressive strength and split-tensile strength with a target density of less than 1800 kg/m³. Various proportions of pumice substitution ranging from 0% to 20%, 40%, and 60% are investigated. The primary objective is to assess the compressive and split tensile strengths of lightweight concrete specimens. Comparative analysis with traditional concrete aims to identify the most advantageous substitution percentage that offers superior strength while meeting structural requirements.
Exploration of the Reform of Cultivating Rural Governance Talents in Universities in the Context of Rural Revitalization
Authors: Wang Haoyu
Published: April 2024

The rural revitalization strategy is a major strategic decision for national development, aimed at promoting thecomprehensive development of rural areas and improving the living standards of farmers. The success of rural revitalization requires full leverage of the role of rural governance, where all individuals from grassroots governments to community residents should take on their responsibilities. The exploration of the reform of cultivating rural governance talents in universities plays a crucial role in cultivating professional talents with knowledge and skills in rural governance. These talents will be able to assist rural grassroots governments in allocating resources, providing social services, and addressing issues, thereby strengthening the implementation of rural revitalization strategies. This article explored the necessity and urgency of the reform of rural governance talent cultivation in universities in the context of rural revitalization, analyzed the opportunities and challenges, and provided useful ideas and inspiration for this reform strategy.
A LEITURA GEO-IMAGÉTICA COMO MÉTODO DE INTERPRETAÇÃO GEOGRÁFICA E SUA CONTRIBUIÇÃO PARA O RACIOCÍNIO E A COMPREENSÃO DE PROCESSOS DE PENSAMENTO
Authors: Copatti Carina
Published: April 2024

A leitura e a interpretação de imagens fazem parte de distintas propostas inseridas nos mais diversos componentes curriculares. Considerando a importância das imagens na construção do conhecimento e, diante disso, a necessidade de rigorosidade metodológica no sentido de construir aportes às pesquisas em âmbito geográfico, o presente artigo tem por objetivo abordar o método de leitura Geo-Imagético (COPATTI, 2019) e debater sua importância tanto na construção do pensamento geográfico do professor quanto no desenvolvimento do raciocínio geográfico em sala de aula. Este artigo constitui-se de um recorte da pesquisa de doutorado, concluída em 2019, a qual, em uma das etapas, utilizou-se desse método para compreender aspectos voltados à análise de respostas obtidas a partir da pesquisa com um grupo de professores de Geografia.
THE FIRST STRUCTURAL CHARACTERIZATION OF A NI(NCS)64– BRIDGED HOMOMETALLIC NI(II) CHAIN DERIVED FROM A N3O DONOR SCHIFF BASE LIGAND
Authors: Chowdhury B. , Nandy R. , Jana N.Ch. , Brandão P. , Panja A.
Published: April 2024

Thiocyanate bridged homometallic Ni(II) chains have potential applications in areas such as molecular magnetism and spintronics due to their tunable magnetic properties. The magnetic properties of these chains are of particular interest and can lead to intriguing magnetic behaviors, such as antiferromagnetic or ferromagnetic interactions. In this context, we have successfully synthesized a Ni(NCS)64– bridge Ni(II) chain complex [Ni2(H2L)2(m1,3-NCS)2(NCS)4]n∙2nCH3CN (1), derived from a tetradentate N3O donor Schiff base ligand (HL). It has been thoroughly characterized by the help of elemental analysis and IR spectroscopy. Single crystal X-ray crystallography has confirmed the geometry of the chain complexes. Both Ni1 and Ni2 centers exhibit hexa-coordination with slightly distorted octahedral geometries, and their coordination environments differ significantly (NiN2O2S2 for Ni1 and NiN6 for Ni2). Within the solid-state structure of the complex, a noteworthy two-dimensional network of hydrogen bonding is observed. The present complex showing a unique example in the realm of single thiocyanato-bridged Ni(II) chains.
E-peer feedback training on L2 writing: A case study of inexperienced learners
Authors: Do Hieu Manh
Published: April 2024

Online peer feedback has been widely applied to teaching L2 writing because of its potential benefits. Accordingly, training is one of the prominent factors contributing to the effectiveness of the activity, especially for inexperienced learners. Acknowledging this significant issue, the current study aims to develop a specific online peer feedback training for inexperienced learners based on their performance naturally during the online peer feedback process, followed by an assessment of its effectiveness. Using the qualitative method design that draws upon the sources of data, including students’ online written comments (Google Docs), oral feedback (Zoom recorded), observations, their drafts, and their reflections and responses through semi-structured interviews, this study presents an in-depth analysis of students’ performance toward peer feedback (without training), how the training is developed, and the impacts of training on the students’ practice. Finally, the study discusses pedagogical implications regarding the instructions and training for online peer feedback in teaching L2 writing, which can be applicably adapted for similar EFL or ESL contexts and learner backgrounds.
A Review on Deep Learning For Electroencephalogram Signal Classification
Authors: Kamil Gatfan Sarah
Published: April 2024

Recently, the research on Electroencephalogram (EEG) signals have been obtained more focus at the same time the EEG signal is regarded as the basis for the prediction of diagnosis disease and the brain behavior. EEG is as significant tool for many conditions that can be recorded the brain human waves which accommodate the brain activity. In the recent decades, EEG data has been extensively applied in the approaches of data analysis such as time series analysis. With the considerable achievement of deep learning (DL) implement on the time series data, multiple studies have been began applying deep learning algorithms on the processing of EEG signal. Several deep learning techniques that assistant in the detection various psycho-neuro disorders, have been proposed in order to automate EEG detection and classification with great development in multiple applications of EEG signals.  Also, different machine learning (ML) algorithms have been presented in such research for brain signals identification and classification in the era of Artificial intelligence (AI). In an attempt to summarize the EEG signal processing techniques, we have performed a literature review around deep learning algorithms for decoding the human’s brain activity as well as diagnosis disease and clarified particulars about several deep learning algorithms. We also conducted some of ML papers about EEG signals classification. Based on the achievement results of the research mentioned in this article appears an advanced scientific development in terms of deep learning.
ENFRENTANDO A EVASÃO: O ARDUINO COMO FERRAMENTA DIDÁTICA EM CURSOS DE ENGENHARIA
Authors: Martins kaio , Silva André Oliveira Carvalho da , Medeiros Lucas Maxwel Fernandes Sales , Lisboa Yasmim Maria Dantas , Maia Lucas Borges , Farias Aleqssandro Alexandre de Oliveira , Lima Júnior Damasio Alves de , Silva Kaylane de Sousa , Miranda Arthur Gutemberg Hora de , Campos Matheus Leão , Couto Thiago Farias , Santos Jhennifer Freitas dos , Fonseca Wellington
Published: April 2024

O trabalho possui por objetivo demonstrar a importância do Arduino como ferramenta didática na formação de profissionais de engenharia, combatendo a evasão que é enfrentada na formação de profissionai
ASSISTÊNCIA DOMICILIAR AO PACIENTE COM INFARTO AGUDO DO MIOCÁRDIO: UMA REVISÃO DE LITERATURA
Authors: pereira Matheus santos samaritano , Silva Victor Hugo Góes
Published: April 2024

Introdução: O infarto agudo do miocárdio (IAM) é uma das principais causas de morte no mundo e no Brasil. O tratamento envolve medidas de emergência e de acompanhamento. A assistência domiciliar (AD)
Atendimento inicial à vítima de trauma
Authors: Ribeiro Taysa Siebra
Published: April 2024

Introdução: O atendimento inicial a vítimas de trauma é primordial para obter a melhor recuperação da vítima e evitar possíveis pioras do quadro clínico. Com isso, a execução do sistema ABCDE é o meca
FINANCIAMENTO EM EDUCAÇÃO: A EDUCAÇÃO DE JOVENS E ADULTOS (EJA) NOS ORÇAMENTOS DA BAHIA
Authors: Silva Marta Rosa Farias de Almeida Miranda
Published: April 2024

O artigo tem por objetivo apresentar estudo sobre o financiamento público da
Educação de Jovens e Adultos (EJA) no Estado da Bahia no período de 2014 a 2017 buscando
evidenciar como a EJA é contemplada nas das Leis Orçamentárias Anuais do Estado. Para
esse fim, fizemos uma breve revisão dos aspectos relativos aos instrumentos de planejamento
no setor público, buscando identificar as principais fontes de financiamento, bem como
conhecer as despesas orçadas pelo Estado destinadas à EJA. Levantamos e analisamos os
dados sobre a evolução dos recursos alocados à Função de Governo Educação e no valor
programado da despesa com Manutenção e Desenvolvimento do Ensino (MDE) com ênfase na
participação da subfunção Educação de Jovens e Adultos. O tema insere-se no campo da
política educacional e, mais especificamente, aos estudos sobre o financiamento, investimento e
orçamentos em EJA. São apresentados resultados de estudos exploratórios, bibliográficos e
documentais. Consideramos que, ainda que preliminares e parciais, os dados apurados alertam
quanto à necessidade e urgência em se aprofundarem pesquisas, visando, entre uma diversidade
de outros aspectos, investigar e analisar o modelo de financiamento, nível de investimento, os
orçamentos e a gestão orçamentária e financeira da Educação de Jovens e Adultos (EJA).
Palavras-chave: Educação de Jovens e Adultos (EJA), Financiamento, Orçamento.
JOSÉ BONIFÁCIO: O PRIMEIRO GEOPOLÍTICO BRASILEIRO?
Authors: Moraes Carlos Henrique Arantes de
Published: April 2024

O presente trabalho busca apresentar a possibilidade de apontar José Bonifácio de Andrada e Silva como um geopolítico brasileiro. Ainda que seu período de atuação na política nacional tenha ocorrido antes do termo geopolítica possuir um campo do conhecimento. Nesse bojo, utilizando-se de uma metodologia qualitativa o objetivo é apresentar que os pensamentos de Bonifácio se assemelham com os pensadores geopolíticos, particularmente aqueles da escola geopolítica brasileira. O estudo faz uma releitura da geopolítica como campo do conhecimento para que se possa fundamentar o objetivo do artigo de aproximar a forma de pensar do “Patrono” da Independência do Brasil com os pensadores geopolíticos.
Os desafios do dia a dia do corpo discente na EJA
Authors: Fideles Gildeny de Carvalho , Araújo Márcia Moreira de
Published: April 2024

A Educação de Jovens e Adultos (EJA) é um território rico em nuances, onde os caminhos da aprendizagem são moldados por experiências únicas e desafios singulares. Este eBook lança luz sobre os desafios do dia a dia enfrentados pelo corpo discente em uma Escola Municipal de Ensino Fundamental no Município de Serra, no estado do Espírito Santo.
SAÚDE DO HOMEM
Authors: Miranda Carolina Barros Gouvêa , Gomes Elizangela Guedes , Trindade Isabel Cristina Ferraz da , Baia Karolyne de Carvalho , Farias Daniele Gonçalves , Almeida Paulo Henrique Vieira de , Alves Jhony Antônio Moraes , Amorim Naiza Almeida , Ladislau Thayane Drosdosky , Martins Janne de Jesus Bugarim , Serrão Mairley Albuquerque , Furtado Wendrel Gonçalves , Gaia Vinicius Ramos , Silva Taynara da Costa , Antonio Carina Lopes de Sousa , Lima Mateus Coutinho de , Oliveira João Vitor da Silva , França Kelly Wanessa da Silva , Lima Arthur Henrique Almeida de , Silva Luciana Tabatha Souza e
Published: April 2024

A saúde do homem, embora frequentemente negligenciada, é um tema crucial para o bem-estar individual e social. Apesar da maior vulnerabilidade masculina a diversas doenças, os homens apresentam menor frequência de visitas à rede de Atenção Primária à Saúde (APS). Essa disparidade exige uma investigação profunda das barreiras que impedem o acesso masculino aos cuidados básicos de saúde. A cultura machista impõe a imagem do homem viril e invulnerável, desestimulando a busca por ajuda médica e reforçando a automedicação. Expressões como "homem não chora" e "homem que é homem não se consulta" perpetuam a ideia de que cuidar da saúde é sinal de fraqueza.
A sobrecarga de trabalho, o compromisso com a família e a priorização das responsabilidades financeiras podem dificultar a busca por atendimento médico. A rigidez da jornada de trabalho masculina também contribui para essa dificuldade. Homens geralmente se sentem menos à vontade para falar sobre suas emoções e problemas de saúde, especialmente em ambientes tradicionalmente femininos como Unidades Básicas de Saúde (UBS). A falta de empatia por parte de alguns profissionais também pode dificultar a comunicação e a confiança.
A carência de profissionais qualificados, horários de atendimento inadequados e a falta de estrutura física adequada nas UBS podem desmotivar o público masculino. A insuficiência de profissionais especializados em saúde do homem também limita o acesso a um atendimento direcionado. A localização distante das UBS, a falta de transporte público e a burocracia para agendamentos podem dificultar o acesso, especialmente para homens que residem em áreas periféricas ou rurais. Dessa forma, a superação dos obstáculos à saúde do homem exige um esforço conjunto dos diversos setores da sociedade. Através da desconstrução de estereótipos, da humanização do atendimento, da ampliação da oferta de serviços e do engajamento da comunidade, podemos construir pontes para um futuro mais saudável para os homens.
ÁLBUM SERIADO DIGITAL PARA O ENSINO-APRENDIZADO DE FAMILIARES DE PACIENTES EM TERAPIA INTENSIVA
Authors: Cruz Luany Rafaele da Conceição , Tavares Helber Freitas , Pantoja Jackeline Pinheiro , Sanches João Victor da Silva , Batista David Vilhena , Seabra Roselane Ferreira , Neves Aline Bento , Lopes Bárbara Cybelle Monteiro , Barbosa Vaneska Tainá Pinto , Oliveira Dyele da Silva de
Published: April 2024

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EDUCAÇÃO EM SAÚDE
Authors: Santos José Paulo Vale dos , Marinho Raísha Ciane Dias , Campos Steffanie Caroline Trindade de , Nascimento Giovana Lima do , Lima Cintia Paula da Silva de , Tyll Milene de Andrade Gouvêa , Brito Luciana Duarte Moreira , Andrade Luis Ricardo Ferreira , Silva Mikely Roseane Mendes da , Wanzeler Larisse Batista , Damasceno Neto Alberto Portilho , Cardoso Maira Isabelle de Miranda , Mendonça Octavio Augusto Barbosa , Pimentel Ester de Jesus da Silva
Published: April 2024

Prezados leitores, esta obra trata de um assunto fundamental para a compreensão sobre as vacinas disponibilizadas pelo Sistema Único de Saúde (SUS), no calendário Nacional de Vacinação. A imunização é indispensável para o controle e prevenção de várias patologias. Contudo, apesar da sua segurança e benefícios, podem gerar alguns efeitos adversos importantes, que devem ser explanados para educação e reconhecimento sobre estes efeitos.
A vacinação é uma das medidas mais eficazes na prevenção de doenças infecciosas, salvando milhões de vidas anualmente. No entanto, como qualquer procedimento médico, as vacinas podem causar efeitos colaterais, conhecidos como eventos adversos pós-vacina (EAPV). Frente a isso, a educação em saúde sobre EAPV é fundamental para garantir a segurança e a confiança na vacinação. Através da informação e do diálogo, podemos fortalecer a cultura de imunização e proteger a saúde da população.
Portanto, ressalta-se que os eventos adversos pós-vacinação podem ser esperados ou inesperados, assim, a sua ocorrência deve ser relatada aos profissionais de saúde, como a equipe de enfermagem, que atua na aplicação dos imunobiológicos. Assim, a educação é necessária para esclarecer dúvidas, mitos e benefícios sobre a vacinação. Diante disso, esta obra pretende abordar sobre a educação em saúde acerca dos eventos adversos causados pelas vacinas.