bluuebunny/crossref_metadata_2025 huggingface dataset:
Định hướng vị trí việc làm và các yếu tố ảnh hưởng của sinh viên năm cuối ngành Y học Dự phòng và Y tế Công cộng Trường Đại học Y Dược Huế
Authors: Thủy Đặng Thị Thanh , Hùng Hoàng Lê Tuấn , Thủy Nguyễn Thị Xuân , Hà Lê Thị , Vui Trần Văn
Published: August 2023

Nghiên cứu mô tả cắt ngang trên 104 sinh viên năm cuối ngành Y học dự phòng và Y tế công cộng Trường Đại học Y Dược Huế năm 2022 nhằm mô tả thực trạng định hướng vị trí việc làm và một số yếu tố ảnh hưởng bằng cách phỏng vấn trực tiếp với bộ câu hỏi soạn sẵn có cấu trúc. Kết quả là 56,7% sinh viên đã có định hướng vị trí việc làm, trong đó 28,8% thay đổi định hướng do ảnh hưởng COVID-19. Hầu hết sinh viên đều gặp khó khăn khi định hướng vị trí việc làm của họ. Có người thân làm trong lĩnh vực sức khỏe (OR = 3,439; 95% CI 1,232 – 9,602) và tự cảm thấy bản thân phù hợp với ngành học (OR = 3,238; 95% CI 1,244 – 8,430) là những yếu tố giúp sinh viên có định hướng vị trí việc làm tốt hơn. Các yếu tố “sở thích công việc”, “kinh nghiệm học tập”, “năng lực phù hợp”, “uy tín công việc”, “cơ hội phát triển”, “cơ hội tham gia nghiên cứu khoa học”, “công việc ổn định”, “dễ xin việc”, “thời gian làm việc linh hoạt”, và “thu nhập cao” là những yếu tố có tác động đến định hướng vị trí việc làm. Các buổi tư vấn định hướng nghề nghiệp, cung cấp thông tin là cần thiết giúp sinh viên có định hướng vị trí việc làm tốt hơn trong tương lai.
Khảo sát sự hài lòng của nhân viên công tác xã hội tại các bệnh viện công lập tỉnh Long An năm 2022
Authors: Hoàng Nguyễn Văn , Nhi Trần Kim , Đức Phạm Tấn
Published: August 2023

Nghiên cứu này là nhằm mô tả mức độ hài lòng, sự gắn bó với nghề nghiệp, ý định chuyển đổi vị trí công tác của nhân viên công tác xã hội cũng như những khó khăn mà nhân viên công tác xã hội gặp phải khi thực hiện nhiệm vụ. Qua khảo sát 76 nhân viên công tác xã hội của 18 bệnh viện công lập trên địa bàn tỉnh Long An cho thấy có 9 (11,8%) nhân viên công tác xã hội “Không hài lòng”, 33 (43,4%) nhân viên công tác xã hội “Chấp nhận được” và 34 (44,7%) nhân viên công tác xã hội “Hài lòng” với công việc. Ngoài ra, nghiên cứu này cũng cho thấy có 32 (42,1%) nhân viên công tác xã hội không muốn gắn bó với nghề nghiệp và 35 (46,1%) nhân viên công tác xã hội có ý định chuyển đổi vị trí công tác. Tỷ lệ nhân viên công tác xã hội gặp phải khó khăn khi thực hiện nhiệm vụ là khá cao (82,9%). Đây là những vấn đề mà các nhà quản lý của các bệnh viện công lập tỉnh Long An cần phải quan tâm hơn trong thời gian tới.
Kiến thức, thực hành tiêm an toàn của điều dưỡng khoa lâm sàng và một số yếu tố ảnh hưởng tại Bệnh viện đa khoa tỉnh Hà Tĩnh, năm 2022
Authors: Thanh Bá Chí , Minh Phạm Đức , Ngọc Lê Bích , Anh Hoàng Tuấn , Cường Uông Quốc
Published: August 2023

Nghiên cứu mô tả cắt ngang kết hợp định lượng và định tính được thực hiện trên 130 điều dưỡng tại 13 khoa lâm sàng Bệnh viện đa khoa tỉnh Hà Tĩnh từ tháng 02 đến tháng 6 năm 2022 nhằm mô tả kiến thức, thực hành tiêm an toàn (TAT) và một số yếu tố liên quan đến thực hành TAT của điều dưỡng. Kết quả cho thấy kiến thức chung về TAT có tỷ lệ đạt thấp là 76,2%. Tỷ lệ điều dưỡng thực hành TAT chung đạt là 76,2%, trong đó tỷ lệ thực hành về kỹ thuật tiêm chiếm tỉ lệ cao nhất (91,5%), còn thực hành về xử lý chất thải và vệ sinh tay sau tiêm thấp nhất (76,9%). Một số yếu tố liên quan như nhóm tuổi 31 - 45, trình độ học vấn đại học là tăng tỷ lệ TAT đạt. Một số yếu tốt khác như đào tạo, tập huấn; trang bị, dụng cụ cũng có vai trò trong việc ảnh hưởng đến tỷ lệ TAT. Bệnh viện cần tăng cường tập huấn về TAT, cũng như chú trọng việc chuẩn bị đầy đủ trang bị, dụng cụ phục vụ cho công tác tiêm thuốc.
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Authors: Loc Nguyen Vo , Mai Truong Tuyet , Thu Nghiem Nguyet , Dung Truong Viet , Trang Tran Thu , Hanh Nguyen Lien
Published: August 2023

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Authors: Chi Nguyen Thi Kim , Thao Duong Quoc , Long Tran Hoang , Loi Cao Ba , Thai Pham Quang
Published: August 2023

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Authors: Uyen Nguyen Quynh , Hong Nguyen Ngoc , Giang Van Huong , Ha Nguyen Duy , Hoang Le Huy , Quyen Huynh Nguyen Minh , Huy Nguyen Quang , Vinh Hoang Van
Published: August 2023

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The medication management in a patient with resistant hypertension with percutaneous endoscopic gastrostomy tube: The role of the clinical pharmacist
Authors: Kelleci Burcu , Ballı Nisa , Savaş Müge , Balcı Cafer , Eşme Mert , Demirkan Kutay , Halil Meltem Gülhan
Published: August 2023

Resistant hypertension (RH) is characterized as a clinical condition in which the patient needs three antihypertensive medications including diuretic for uncontrolled blood pressure (BP). Treatment of RH involves improving medication adherence and correct administration. Medication administration may be the key point when the patients’ clinical conditions are not applicable for oral drug administration. Thus, comprehensive investigation of the patient is extremely important to identify the right medication, administration route, and time. In this case report, BP control was not achieved despite consulting several related medical services/departments for the patient with gastrostomy and uncontrolled RH. Thereafter, BP was gradually decreased with the intervention of the clinical pharmacists based on detailed research about the appropriateness of drug administration through percutaneous endoscopic gastrostomy (PEG) tube and timing. Drug administration via a PEG tube or feeding tube can be challenging at some points. Although drug–drug interactions can be recognized easily, potential drug–nutrient interactions should be also considered.
Beslenme Destek Tedavisinde Oral Nütrisyonel Destek Ürünleri Kullanımı: KEPAN Rehberi
Authors: Bahat Gülistan , Akmansu Müge , Güngör Levent , Halil Meltem , Hopancı Bıçaklı Derya , Koç Nevra , Özoğul Yusuf , Sungurtekin Hülya , Abbasoğlu Osman
Published: August 2023

Beslenme desteği, hasta tedavisin ayrılmaz bir parçasıdır. Bununla birlikte, günlük uygulamalarda beslenme tedavisi hedeflerine ulaşıldığını söylemek zordur. Bu nedenle klinik pratikte beslenme tedavisi uygulamalarını kolaylaştırmaya yönelik girişimlere ihtiyaç vardır. Malnütrisyon tedavisinde ilk seçenekler diyet düzenlemesi ve oral tamamlayıcı nütrisyon ürünleri (ONS) kullanımıdır. Tüm dünyada tıp fakültesi, beslenme ve diyetetik fakültesi ve uzmanlık eğitimi müfredatları klinik beslenme konusunda genellikle yeterli değildir. Hekim, diyetisyen, hemşire, eczacı ve diğer sağlık profesyonellerine yönelik, ONS kullanım endikasyonları, ürünlerin seçimi ve uygulanma şekli, hasta izlemi ve tedavi sonlandırılmasında yol gösterecek kısa, net ve pratik önerilere odaklı bir rehberin yararlı olacağını düşündük. Bu rehber, alanında deneyimli uzman bir ekip tarafından KEPAN çatısı altında hazırlanmış ve 28 kişiden oluşan KEPAN rehber grubunca onaylanmıştır.
ANALISIS SPASIAL PRIORITAS PENANGANAN STUNTING DI PROVINSI ACEH TAHUN 2021
Authors: Sakti Eka Satriani , Makful Martya Rahmaniati , Dewi Romariana
Published: August 2023

Stunting adalah kondisi tubuh pendek yang tidak sesuai dengan kurva pertumbuhan tinggi/panjang badan berdasarkan usia yang disebabkan oleh gangguan gizi kronis. Prevalensi stunting tahun 2021 di Indonesia adalah 24,4%, belum mencapai target penurunan yang ditetapkan WHO yaitu 20%. Prevalensi stunting di Provinsi Aceh masih tergolong tinggi yaitu 33,2%. Tujuan dari penelitian ini adalah untuk mendeskripsikan dan memetakan faktor-faktor yang berkorelasi dengan stunting sehingga dapat ditentukan daerah prioritas penanganan stunting di Provinsi Aceh. Penelitian merupakan studi deskriptif ekologi dengan menggunakan Sistem Informasi Geografis. Sumber data dari Studi Status Gizi Indonesia (SSGI) tahun 2021 dan Profil Kesehatan Aceh tahun 2021. Klasifikasi berdasarkan standar WHO untuk prevalensi stunting dan metode natural breaks (jenks) untuk variabel faktor-faktor yang berkorelasi dengan stunting. Penentuan daerah prioritas dilakukan dengan akumulasi hasil skoring seluruh variabel untuk masing-masing kabupaten/kota. Hasil analisis diketahui kabupaten/kota prioritas 1 adalah Kabupaten Pidie, Bireun, Aceh Tamiang, Aceh Timur, Aceh Besar, dan Aceh Utara. Saran dilakukan intervensi penanganan stunting pada wilayah prioritas 1 dan diperlukan analisis lanjutan penentuan daerah prioritas penanganan stunting tidak hanya berdasarkan variabel di penelitian ini, tetapi juga variabel yang berkaitan dengan intervensi gizi sensitif sehingga penentuan daerah prioritas dapat lebih tepat.
HUBUNGAN DUKUNGAN KELUARGA DAN KUALITAS HIDUP LANSIA PENDERITA DM TIPE II DI PUSKESMAS BAKTIRAJA, HUMBANG HASUNDUTAN
Authors: Sijabat Flora , Siregar Rinco , Barus Darwita J
Published: August 2023

The impact of diabetes mellitus includes physical, psychological and social changes in sufferers. One of the common psychological changes experienced is anxiety. Support from family for people with type 2 DM in the form of emotional attention, practical assistance, and assesments provided by family members can help improving physicaly and mental well-being of sufferers and is an important form of social support. This study aims to evaluate the relationship between family support and the quality of life of elderly peopple with type 2 diabetes mellitus at the Baktiraja Health Center, Humbang Hasundutan District. This study used a quabtitative approach with a correlative descriptive method and a cross-sectional design. The research sample consisted of 65 respondents. The result showed that there was a significant relationship between family support and the quality of life of elderly people with type 2 diabetes mellitus at the Baktiraja Health center, Humbang Hasundutan District (p = 0,000). The involvement of family support for human type 2 DM has an importance role in improve heir quality of life. Therefore, health workers can provide appropriate nursing interveitions. One way that’s can be do by nurses to increase family’s support is to provide knowledge through health education and counseling to sufferers and families.
Analysis of Anions Distribution in Gobbiya Dam Water, Bogoro Local Government Area of Bauchi State by GIS
Authors: Sumdhin Gad Dauda , Mahmoud Auwal Adamu , Adamu Haruna , Afsa Shiphrah Retu , Raymond Wisdom
Published: August 2023

Water quality is one of the main challenges that societies faces, threatening human health, limiting food production, reducing ecosystem functions, and hindering economic growth. In this research water sample from Gobbiya dam were collected at ten different points on the dam water surface using a water sampler with the coordinate of the sampling point recorded using a Global Positioning System (GPS) camera. Powder pillow reagents with a DR/890 colorimeter was used to determine the level of anions in the water samples after which Geographical information system (GIS) were used to estimate by interpolation the levels of anions at unmeasured distance on the dam water surface. The result obtained showed that the concentration of sulphate and phosphate has no statistical difference across the ten sampling points as revealed by ANOVA (P≤0.05) ,Whilst Chloride, Nitrate, Ammonium showed a statistical differences across the ten sampling points and where further subjected to Turkey Pair-Wise test to determine the points of variation. The average concentrations of the anions determine are as follows: Phosphate, Chloride, Nitrate, Ammonium, Sulphate (0.06±0.01, 0.48±0.24, 14.4±10.30, 3.95±2.82, 2.40±0.97) mg/dm3, respectively. The anions determined in the dam water are within the permissible limit set by WHO and FEPA for domestic and irrigation purposes.
Effect of the Use of Information and Communication Technology on The Instruction of Physics in Secondary Schools in Awka Education Zone of Anambra State
Authors: Egolum Evelyn Obianuju , Sunday Chime, Chukwuma
Published: August 2023

This study examined the effect of the use of information and communication technology on the instruction of physics in secondary schools in Awka Education Zone of Anambra state. The study was guided by the three research questions and three hypotheses. The population for the study was 19, 153 SS3 physics students in all the secondary schools in the study area. A sample size of 110 SS3 physics students were selected (59 males and 51females). The research instrument used for the study was a Physics Achievement Test (PAT). PAT was validated by three experts, one lecturer from science education department, one from educational foundations department and one from computer science department, all from Nnamdi Azikiwe University Awka. A reliability coefficient of 0.86 was gotten using Kudar- Richarson’s reliability formula. The mean and standard deviation were used to answer the research questions while Analysis of Variance (ANOVA) was used to test the null hypotheses at 0.05 level of significance. The findings of the study showed that students taught physics with ICT performed higher than their counterparts that were taught physics without ICT. Gender interaction effect showed that the male students taught with ICT performed higher than their female counterparts. Based on the findings of this study, it was recommended among others that physics teachers should be encouraged to use ICT in teaching physics, since the method is more effective in learning physics compared to the conventional lecture method Also the federal ministry of education should organize workshops and seminars for science teachers to strengthen their knowledge of the use of ICT in teaching.
Bridging Educational Gaps Among University Students During the New Normal through the Kumustahan Project: A Focus Group Discussion Initiative for Higher Education
Authors: Paras Percival S. , Ferranco Achilles Alfred C.
Published: August 2023

I. Introduction A year after World Health Organization declared Covid-19 as a global pandemic, most universities across the world are still struggling to face the new normal. Online learning has become the means universities have in continuing education. While most progressive universities are digitally prepared, there is another gap that these universities have to deal with – the continuing divide between those who are able to study digitally, and those that are left behind due to economic factors. In a recent study by Grishchenco (2020), most of the students living in rural areas have been greatly affected by the sudden shift to full digital learning due to the limitations of technology. Beaunoyer, Dupéré, and Guitton (2020) pointed out that the digital divide has already been existing even in the pre-pandemic days. It, however, exacerbated when students were left with no other means but through online learning. The series of lockdowns caused a lot of limitations to the students. From technological limitations to financial and even social challenges (Lassoued, Alhendawi, & Bashitialshaaer, 2020; Peters, et al., 2020), students are also challenged when it comes to their mental health and psychological wellness (Cao, et al., 2020), causing greater issues on inclusion – both academically and socially. In the Philippines, the readiness of students in a fully-digital learning space remains low on students’ demographics who belong to lower income and rural areas (Alipio, 2020). Approximately 2,400 Higher Education Institution in the Philippines are challenged to bridge the gap between the economically-able students and those who are being left behind. Prior to the 2020 Pandemic, Oztok et al. (2013) surveyed different means of conducting digital learning to alleviate such gap, through synchronous and asynchronous learning. Years later, the acceptance of synchronous and asynchronous mode of online learning has become a staple in the New Normal set-up of education.
Transmission Dynamics of Peste des petit ruminant (PPR) in sheep and goats: A Mathematical Modelling Approach
Authors: S. Bashir , A. Muhammad , I. D. Garba
Published: August 2023

The study is mainly concerned with mathematical modelling of peste des petit ruminant (PPR) disease using deterministic approach. A system of differential equations was formulated. Disease free and epidemic equilibria were calculated and used Jacobian Matrix to carried out stability analysis of the model. We then perform numerical simulations using Euler’s method. Sensitivity analysis with basic reproduction number were finally conducted to identify the most important parameters in the model. It was finally recommended that animal suffering from peste des petit ruminant (PPR) diseases should be immediately quarantined so as to reduce the contact rate between the infected and the susceptible and other items that have been in contact with the sick animals must be disinfected with common disinfectants.
EDUTAINMENT ЯК СУЧАСНА ІННОВАЦІЙНА ТЕХНОЛОГІЯ
Authors: Михалюк А. М.
Published: August 2023

Edutainment — це інноваційна технологія, яка поєднує розважальні методи й активне навчання з метою створення ефективного балансу між інформацією та розвагами. За допомогою сучасних техно­логій і мультимедійних продуктів Edutainment може бути використана для подання складних тем у легкій розважальній формі, що сприяє розвантаженню психіки студентів. Як стверджує Мікела Еддіс, техноло­гія Edutainment поєднує в собі розважальні прийоми та методи інтерактивного й активного навчання з метою мотивації до пізнання та взаємодії. Вона є ефективним поєднанням інформації, мультимедійних продуктів, психологічних прийомів та сучасних технологій, що допомагає створювати баланс між осві­тою та розвагами. Шерон Де Варі вважає, що Edutainment є важливим інструментом для ефективного навчання та розвитку, і це уможливлює залучення учнів до навчального процесу і робить його цікавим та змістовним. Роб Донован наголошує на можливостях Edutainment для подання складних тем у розва­жальному характері задля зменшення навантаження на психіку студентів. Технологія Edutainment може бути використана у сферах навчання — від шкільної освіти до вищої освіти і освіти дорослих. За допомо­гою Edutainment можна підвищити зацікавленість студентів до навчання і сприяти більш ефективно­му засвоєнню матеріалу ними. Водночас українські вчені розуміють технологію Edutainment як сукупність сучасних засобів навчання, що поєднують у собі дидактичні, інформаційні й ігрові елементи з метою пе­редачі знань та розвитку вмінь і навичок. Крім того, вони відзначають, що використання розважальних методик та інформаційних технологій сприяє задоволенню цікавості та глибокому захопленню пробле­мою, що допомагає більш ефективному навчанню. У статті висвітлено авторське тлумачення поняття «Edutainment» як інноваційної освітньої технології, яка складається з технічних і дидактичних засобів нав­чання, заснована на концепції навчання через розвагу, спрямована на передачу знань, досвіду та забезпечує формування вмінь і компетентностей в активній практичній діяльності. Розкрито важливість техно­логії Edutainment у процесі загальнопедагогічної підготовки студентів вищої освіти, що сприятиме збіль­шенню їх зацікавленості і мотивації до навчання, забезпеченню конкурентоспроможності та підвищенню професійної мобільності. Використання ігрових технологій допоможе формуванню здатності вільно спіл­куватися в освітньому процесі з урахуванням індивідуальних запитів та можливостей здобувачів вищої освіти. Представлено результати опитування серед здобувачів першого (бакалаврського) рівня вищої освіти, яке засвідчило ефективність застосування технології Edutainment у процесі загальнопедагогічної підготовки здобувачів вищої освіти.
EFEKTIVITAS ANTOSIANIN EKSTRAK BUNGA MAWAR UNTUK PENGOBATAN DIABETES MELLITUS TIPE 2
Authors: KURNIAWAN WAWAN
Published: August 2023

Hyperglycemia is a medical condition in the form of an increase in blood glucose levels beyond normal which is a characteristic of several diseases, especially diabetes mellitus, in addition to various other conditions. Indonesia's rich edible tropical flowers have become part of the archipelago's cuisine, traditionally used as medicine, as natural dyes for food and beverages. Anthocyanins are polyphenolic compounds whose existence is very abundant in nature with diversity in various types of plants. Anthocyanins are natural components that accumulate in vacuoles and are responsible for the red, blue and purple colors in fruits, vegetables, flowers and other plants. Various positive benefits of anthocyanins for human health are as antioxidants, improve eye vision, anti-inflammation, prevent diabetes, inhibit tumor cells and prevent neurological diseases.
ABSTRAKHiperglikemia adalah suatu kondisi medis berupa peningkatan kadar glukosa darah melebihi normal yang menjadi karakteristik beberapa penyakit terutama diabetes melitus di samping berbagai kondisi lainnya. Kekayaan bunga-bunga tropis di Indonesia yang dapat dimakan telah menjadi bagian dari kuliner nusantara, secara tradisional digunakan sebagai obat, sebagai pewarna alami untuk makanan dan minuman. Antosianin merupakan senyawa turunan polifenol yang keberadaannya sangat melimpah di alam dengan keanekaragaman dalam berbagai jenis tumbuhan. Antosianin adalah komponen alami yang terakumulasi pada vakuola dan bertanggungjawab untuk warna merah, biru dan ungu pada buah, sayur, bunga dan tumbuhan lainnya. Berbagai manfaat positif dari antosianin untuk kesehatan manusia adalah sebagai antioksidan, meningkatkan kemampuan penglihatan mata, anti inflamasi, mencegah diabetes, menghambat sel tumor dan mencegah penyakit neurologis.
ANÁLISE DOS ACIDENTES DE TRABALHO EM UM MUNICÍPIO INDUSTRIAL DO CEARÁ
Authors: Rocha Samille Marques Bulcão , Silva Gyselle de Oliveira , Cruz Helânia do Prado , Benevides Marina Layara Sindeaux
Published: August 2023

Introdução: O trabalho é fundamental na vida das pessoas, é por meio deste que o homem mantém o seu sustento e de sua família. Os riscos inerentes a saúde do trabalhador são previsíveis e, portanto, passíveis de prevenção. Objetivos: Analisar os acidentes de trabalho em um município industrial do Ceará. Métodos: Trata-se de uma pesquisa descritiva, com coleta de dados documental e análise quantitativa, mediante notificações de acidentes de trabalho nos anos de 2018-2019. Resultados: Foram encontradas 67 notificações, onde 64,18% corresponderam aos Acidentes de Trabalho Grave e 35,82% aos Acidentes com exposição a material biológico. A população jovem e parda foi a mais atingida, representando 97,67% em relação aos acidentados graves e 79,16% acidentados por exposição a material biológico. Quanto à ocupação dos acidentados, dentre os acidentes de trabalho grave, 20,93% eram operadores de máquinas, 11,63% pedreiros e 9,30% auxiliares de produção. Quanto aos acidentados com material biológico, 100% pertenciam à saúde e destes, 33,33% eram Técnicos de Enfermagem A mão foi a região mais acometida, seguida pelos membros inferiores. Conclusão: Conclui-se que faz-se necessário ações educativas e uma maior participação da gestão na construção de ferramentas que garantam a integralidade da Saúde do trabalhador.
A BASE NACIONAL COMUM CURRICULAR NA EDUCAÇÃO INFANTIL: DESAFIOS NA IMPLANTAÇÃO
Authors: Silva Cleusa Feniman da , Feniman Neusa
Published: August 2023

A Base Nacional Comum Curricular (BNCC) é um documento normativo que estabelece os conhecimentos, habilidades, competências e valores essenciais que todos os alunos devem desenvolver ao longo de sua trajetória educacional. No contexto da educação infantil, a implantação da BNCC apresenta desafios significativos. Este artigo tem como objetivo abordar os desafios enfrentados na implantação da BNCC na educação infantil e as possíveis soluções para superá-los.
An age scale for new climate records from Sherman Island, West Antarctica
Authors: Rowell Isobel , Martin Carlos , Mulvaney Robert , Pryer Helena , Tetzner Dieter , Doyle Emily , Talasila Hara Madhav , Li Jilu , Wolff Eric
Published: August 2023

Abstract. Few ice cores from the Amundsen Sea and Bellingshausen Sea sectors of the West Antarctic Ice Sheet (WAIS) extend back in time further than a few hundred years. The WAIS is believed to be susceptible to collapse as a result of anthropogenic climate change and may have at least partially collapsed during the Last Interglacial (LIG) period. Understanding the stability of the WAIS during warm periods such as the LIG and Holocene is important. As part of the WACSWAIN (WArm Climate Stability of the West Antarctic ice sheet in the last INterglacial) project, the British Antarctic Survey's (BAS) Rapid Access Isotope Drill (RAID) was deployed in 2020 on Sherman Island in the Abbot Ice Shelf, West Antarctica. We drilled a 323 m deep borehole, with discrete samples of ice chippings collected that cover the entire depth range of the drilled ice. The samples were analysed for stable water isotope composition and major ion content at BAS from 2020–2022. Using annual layer counting of chemical records, volcanic horizon identification and ice modelling, an age scale for the record of 1724 discrete samples is presented. The Sherman Island ice record extends back to greater than 1240 years, providing the oldest, continuous ice-derived palaeoclimate records in the coastal Amundsen and Bellingshausen Sea sectors to date. We demonstrate the potential for recovery of a complete Holocene climate record from Sherman Island in the future and confidence in the ability of RAID samples to contain sufficiently resolved records for meaningful climatic interpretation.
The functional role of a GWAS identified microRNA in prostate cancer
Authors:   , Lalkota Bhanu Prakash
Published: August 2023

MicroRNAs (miRNAs) are small RNA species that act as master regulators in cancer by simultaneous regulation of multiple genes. In cancer cells, the lack of natural miRNA function and consequent uncontrolled oncogene expression leads to tumorigenesis. This study aimed to analyse the functional role of a specific miRNA, shorlisted via previous genetic association study. Stable overexpression cell lines harboring this miRNA were established, and its functional role was confirmed using cell proliferation, migration and invasion assays. Moreover, in vivo analyses confirmed the potential of our shortlisted miRNA for the "miRNA replacement therapy" to treat prostate cancer.
Revolutionary Target-Based Approaches Inscribing the Pathogenesis of Psoriasis
Authors: Dobariya Mansi , Goswami Sunita
Published: August 2023

Psoriasis is a chronic, non-communicable, painful, disfiguring, and disabling disease for which there is no cure and it considerably affects a patient’s quality of life. This article has considered an in-depth review using various search methodologies which describes the pathogenesis of psoriasis and target-based approaches. The findings in pathogenesis include many approaches from epidermal hyperplasia to immune-mediated, chronic inflammatory, genetic and autoimmune mechanisms. Psoriasis seems to be a feedback system of immune cells running beneath the skin. The development of precisely targeted therapy is possible with a detailed understanding of disease pathophysiology. So, the present review comprises insights into pathophysiology and target-based approaches for psoriasis therapy.

Keywords: Pathogenesis, Targets, Immune cells, cellular mechanisms, Signal transduction pathways, biologics
Applying Diversion and Restorative Justice in Juvenile Narcotics Cases at the Binjai District Court, North Sumatera, Indonesia
Authors: Hasibuan Lidya Rahmadani , Marbun Rika Jamin
Published: August 2023

The problem of drug abuse involving Narcotics, Psychotropics, and other Addictive Substances is a specialized criminal offense with widespread national and international implications, causing adverse effects on society, the nation, and the country as a whole. In this context, the role of the law is crucial in addressing and combating this criminal activity through the implementation of criminal law policies, as part of the broader efforts in law enforcement. The research objective is to examine the Juridical Review of the Implementation of Rehabilitation Institutions during the Prosecution Stage by the Prosecutor's Office in cases of drug abuse, with a specific focus on Narcotics. The study aims to gain insights into how Rehabilitation Institutions are applied by the Prosecutor's Office during the prosecution stage, following the guidelines outlined in the Attorney General's Directive No. 18 of 2021.
Imposing prison sentences on individuals, especially minors, who fall victim to drug abuse involves the deprivation of their freedom and carries negative implications, making it challenging to fully realize the goals of punishment. In the context of the Binjai District Court, measures are taken to provide a protective environment for children facing legal issues, enabling them to be diverted through the principles of Restorative Justice. Conversely, Rehabilitation is designed to help individuals categorized as drug addicts overcome their dependency on narcotics. The process of resolving drug abuse cases through rehabilitation places emphasis on restorative justice and the potential benefits, taking into account principles of expeditious and uncomplicated justice with minimal costs, the principle of using criminal measures as a last resort, cost and benefit analysis, and the recovery of the offenders involved.

Keywords: Restorative Justice, Narcotics, Juvenile Offenders
A Study to Determine the Knowledge, Attitude and Usage of Traditional (AYUSH) Systems of Medicine among the Students Seeking Admission to the Bachelor in Homoeopathic Medicine and Surgery (BHMS) Course - Telangana, India
Authors: Bevinamarad Sneha , V. Patil Priya
Published: August 2023

AYUSH system of medicines consists of seven systems - Ayurveda, Yoga, Naturopathy, Unani, Siddha, Sowa- Rigpa, and Homeopathy.1 Apart from these many other systems like, acupuncture, Chinese medicines, Chiropractic and osteopathic medicine, etc. are included under Complementary and Alternative medicines (CAM). In India, only the above-mentioned. AYUSH systems and educational courses related to these systems are considered under medical stream. AYUSH medicines though are popular among people, the knowledge regarding these systems in medical science and medical course is not evident. Hence this study is aimed to estimate the knowledge, attitude towards, and usage of AYUSH systems of medicine among the students seeking admission to the BHMS course.
Materials and Methods: For this observational, cross-section study, a total of 132 students of both sexes, seeking admission to the BHMS course between October 2022 to May 2023, were selected by random sampling. A closed-ended, self-structured online questionnaire was used after validation and approval, to assess the knowledge, attitude towards and usage of the AYUSH system of medicines. Descriptive statistical analysis was done using MS EXCEL.
Result: The study revealed that students had good knowledge and positive attitudes towards AYUSH systems. 74% of students had used AYUSH medicines at least once. 84% of students willingly joined the course. The most popular system was Homoeopathy, while no student was aware of Sowa-Rigpa as the system of medicine.
Conclusion: This study concludes that the knowledge and attitude among the students seeking admission to the BHMS course, regarding Homoeopathy is good compared to other AYUSH systems.

Keywords: Alternative; Complementary; AYUSH; Traditional; Attitude; Knowledge; Usage; BHMS
Psychological Distress of Infertility and Assisted Reproductive Technology: Psychosocial Management Modalities of Clients
Authors: R.O. Aina , C.A. Owopetu , I.Y. Ademuyiwa
Published: August 2023

Infertility is the inability of couples to achieve pregnancy within one year of regular unprotected sexual intercourse. It affects around 8 to 12% of reproductive-aged couples globally, with one-third of cases caused by male issues, one-third by female issues, and one-third by a combination of both or unknown factors. Several treatment options abound and the couple may need to be managed through Assisted Reproductive Technology (ART). Infertile couples often experience psychological distress in the form of stress, anxiety and depression with a diagnosis and treatment with ART. It is therefore important to provide psychosocial support and appropriate coping strategies during infertility treatment, as couples may lack information and strategies to deal with the psychological impact. These are actions that address both the psychological and social needs of the couple. Though very important, there is limited research on the efficacy of psychological interventions for couples undergoing assisted reproductive technology (ART) treatment, particularly in Africa.
Reengineering Supervisory Practices for Effective Goal Attainment in Public Senior Secondary Schools in Rivers State
Authors: T.J. Nwuke , R. Soli
Published: August 2023

This study examined reengineering supervisory practices for effective goal attainment in public senior secondary schools in Rivers State. The study was guided by three research questions. The research design employed in this study was a descriptive research design. The population of the study comprised all supervisors in the ministry of education and the Rivers State senior secondary school board. The total population of supervisors in the Ministry of Education is one hundred and ninety-one (191), and supervisors in the Rivers State Senior Secondary Schools Board are one hundred and thirty-one (131). Hence, the population for this study is three hundred and twenty-two (322). The sample of the study is composed of three hundred and twenty-two (322) supervisors in the Rivers State Ministry of Education and the Rivers Senior Secondary Schools Board. The census sampling technique was adopted. This technique is considered most appropriate because the population of the study is quite small and can be managed. However, out of 322 copies of the instrument distributed, 280 were correctly filled and returned, which represented an 87% return rate of the instrument distributed and used for data analysis. The instrument that was used for data collection was a self-constructed questionnaire titled Reengineering Supervisory Practices for Effective Goal Attainment Questionnaire (RSPEGAQ). Reliability for the study was determined using the Cronbach alpha coefficient statistics. The reliable index yielded a result of 0.892, which showed that the instrument was reliable and was adopted for the study. Mean and Standard Deviation Statistics were used to answer the research questions. Through the implementation of supportive supervision models that foster a culture of self-reflection, public schools can witness notable enhancements in the achievement of objectives, professional development, collaboration, accountability, and instructional leadership. The study recommends, among other things, that a systematic approach be implemented, involving administrators, teachers, and other relevant stakeholders, in order to establish goals. This approach should prioritise open communication and shared decision-making to ensure that these goals are in line with the school's vision and long-term objectives.
Surgical approach to forearm pronation deformity in patients with cerebral palsy: a systematic review
Authors: DE LEPELEERE Bram , FORWARD Malcolm , MARTENS Manuel , PLASSCHAERT Frank
Published: August 2023

Background: Pronation deformity in patients with cerebral palsy can have a major impact on upper limb functionality. There is lack of consensus in the literature about the preferred surgical technique to address this deformity.

Study aim: To evaluate and synthesize the outcome of different surgical techniques for pronation deformity in patients with cerebral palsy.

Methodology: The databases MEDLINE and Embase were searched for publications up to December 2021. Articles were considered eligible for inclusion when the included patients had a pronation deformity caused by cerebral palsy and results of surgical intervention for pronation deformity were examined. Evaluation of the quality of the retrieved study was conducted using the MINORS tool. Meta-analysis was not possible due to the heterogeneity of interventions and reported outcomes.

Results: Nineteen studies, involving 475 patients and eight different techniques were included. All studies reported gain of active supination in most patients. The effect of surgery on functional gain was less clear and there was a large heterogeneity of reported functional outcome measures. There were 46 reported complications. Overall quality of study design was poor, illustrated by the average MINOR score of 6.9/16. Overall, there is a high risk of bias due to poor internal and external validity of the studies.

Conclusion: Despite positive reports on gain in supination and functionality after most procedures addressing pronation deformity in CP patients, no conclusions can be drawn concerning the preferred technique due to the low quality of the evidence.
Results of Ilizarov external fixator lengthening compared to lengthening and then plating in management of femoral shortening in children
Authors: EL-ADLY Wael , EL-GAFARY Kamal , KHASHABA Ahmed , KHALED Mohamed
Published: August 2023

Femoral shortening in children is a challenging condition with complex functional and psychological implications. We study the results of Ilizarov external fixator (IEF) lengthening compared to lengthening and then plating (LAP) in the management of femoral shortening in children. Forty patients were included in the study and equally divided randomly into 2 groups, in group I LAP was used and in group II lengthening by IEF only was done. The two groups were analyzed for postoperative variables to adjudge the surgical outcomes. The mean follow up time was 24.05 ± 2.99 months, The gained length was 5.60 ± 0.60 cm in group 1 and 5.48 ± 0.64 cm in group II, group I had a shorter external fixator period (3.96 ± 0.22) months, better healing index (24.6 ±2.76) days/cm, earlier complete weight-bearing (5.55 ± 0.78) months than group II. The period of hospitalization for group I was longer more than group II. The complications were less in group I (n=7, 35%) than in group II (n=11, 55%). There was no significant correlation between the healing index with age, also no significant difference was detected between the healing index and gender. There was a significant correlation between the gained length and complete weight-bearing. This study efficiently demonstrates that LAP may be better than lengthening with IEF alone in the management of femoral shortening in children.
China-Pakistan Space Cooperation: Path, Motivation And The Future
Authors: Kuang Ho Yeh , Guihua Ni
Published: August 2023

After the founding of the People’s Republic of China, friendly bilateral relations between China and Pakistan have become increasingly close in various fields following China’s peaceful rise. The space cooperation that started after the end of the Cold War is a sign of the gradual progress of the relationship between the two countries to the current all-weather strategic cooperative partnership. With China’s assistance, Pakistan has achieved significant milestones in the space field. Pakistan is also a key node in China’s strategy to expand international space cooperation. After the 2010s, China-Pakistan space cooperation was integrated with the construction of the Space Silk Road and the China-Pakistan Economic Corridor under the framework of the Belt and Road Initiative, becoming a model for space cooperation specifically promoting the social and economic development of developing countries. This paper outlines the complete picture of China-Pakistan space cooperation under the evolutionary logic and chronological context of "ideological-materialization" two-way mutual construction, so as to reasonably predict the prospects of China-Pakistan space cooperation.
Some Aspects Of The Algerian-Russian Military Cooperation: The Features And Prospects
Authors: Gasparyan Aram
Published: August 2023

The article examines the military cooperation between Algeria and Russia, which is of key importance for bilateral relations. The cooperation between the two countries intensified and received a new impetus during the presidency of Abd al-Aziz Bouteflika and Vladimir Putin. In a short time, Algeria became the largest buyer of Russian weapons in the Middle East and North Africa, which, together with the revenues from the sale of oil, strengthened Algeria's position and increased its influence in the region. At the same time, military cooperation with Russia had a significant impact on the development of political relations between the two countries. Algeria gradually became an important strategic partner for Russia in North Africa. In presenting the Russian-Algerian military cooperation, it is important to highlight certain aspects that have had both positive and negative effects on this partnership during different periods. These aspects include a shared desire for strengthening positions, as Russia and Algeria have shown a mutual interest in bolstering their positions and influence in the Middle East and African region; political cooperation and similarity of positions on a number of international issues; and the Russian- Ukrainian war, which had and has some impact on military cooperation.
Epidemiologia das doenças do apêndice em adultos nos anos de 2019 e 2020 no Brasil
Authors: Nogueira Paulo Luiz Batista , Fonseca Lucas Hortolam , Barbosa Luiz Eduardo Okada , Parisi João Villar Souza , Martins Arnaldo Barbosa , Nunes Guilherme Pavini , Martins João Guilherme Dos Santos , Lope Júlio Lúcio Mello , Neves Lucas Fernandes , Bezerra Luis Otávio Tábuas , Carvalho Vinicius Dal Ponte
Published: August 2023

A apendicite aguda no Brasil tem uma prevalência elevada e é responsável por uma grande quantidade de internações hospitalares e cirurgias de emergência. A ocorrência é maior entre homens com faixa etária comum em adolescentes e adultos jovens. O tratamento de escolha é a apendicectomia laparoscópica e apresenta baixa incidência de mortalidade. Objetivo: Identificar os fatores epidemiológicos das hospitalizações por doenças que acometem o apêndice vermiforme ocorridas no Brasil entre janeiro de 2019 e dezembro de 2020. Métodos: Trata-se de um estudo epidemiológico, observacional, analítico de corte transversal utilizando dados do Sistema de Internações Hospitalares nos anos de 2019 e 2020. Foram incluídos pacientes maiores de idade, internação em caráter de urgência, especialidade do leito como cirúrgico e com diagnóstico principal preenchido com códigos CID-10 referente às doenças do apêndice, com as seguintes variáveis: ano e mês de competência, caráter da internação, idade, diagnóstico principal, dias de permanência, utilização de UTI, evolução, região de residência, número da AIH, procedimento realizado, raça/cor, sexo e valor total. Resultados e Conclusão: Foram observados um total de 155.430 hospitalizações, com idade média de 35,35 anos, maioria pertencente ao sexo masculino e a raça/cor branca ou parda. A evolução por alta foi predominante e o custo hospitalar médio de R$ 702,00 sendo a região mais prevalente no Brasil o Sudeste.Palavras-Chave: Apendicite; COVID-19; Hospitalização; Epidemiologia.
A importância da imuno-histoquímica para abordagem terapêutica de meningioma em fossa nasal
Authors: Santos Caio Carvalho , Domingos Olívia Gabriela de Jesus , Koch Tammiress Braz , Garrido Ana Luiza Moraes , Kondo Dennis Frank , Villasboas Paulo Lucas Benchimol , Metello Maria Julia Medeiros , Moussalem Guilherme Figner
Published: August 2023

Os meningiomas são os tumores cerebrais primários mais comuns.Síndromes genéticas, radiação ionizante e traumatismo cranianosão associados a um risco aumentado para o seu desenvolvimento.A recorrência mesmo após sua ressecção é um dos problemasmais relevantes no tratamento. Evidencias atuais apontam que aprogesterona pode contribuir para o crescimento e a recorrência dotumor.Palavras-Chave: Meningioma; Recorrência; Progesterona.
Zagrożenia cybernetyczne w funkcjonowaniu administracji publicznej powiatu jarosławskiego
Authors: Kupińska Katarzyna
Published: August 2023

W czasach coraz powszechnej i ogólnodostępnej cyfryzacji i jednocześnie porozumiewania się za pośrednictwem sieci teleinformatycznych sprawa bezpieczeństwa systemów IT przestaje być tylko przedmiotem zainteresowania małej grupy ekspertów i specjalistów w tej dziedzinie. Bezpieczeństwo cybernetyczne ma szczególne znaczenie w prawidłowym funkcjonowaniu administracji publicznej na poziomie gminnym i powiatowym, gdzie istnieje potrzeba nieustannego podnoszenia kompetencji przez pracowników tych instytucji, co potwierdziły przeprowadzone badania w powiecie jarosławskim.
Determination of the efficacy of human Chorionic Gonadotropin (hCG) administrations on reproductive performance, placentation, parturition, and neonatal parameters on different post–mating days in Kangal ewes sexually induced during anestrus
Authors: Takci Abdurrahman , Kivrak Mehmet Bugra
Published: August 2023

This study aimed to determine the efficacy of post mating human Chorionic Gonadotropin (hCG) during anestrus on the formation of the accessory corpus luteum and some reproductive parameters. For this purpose. after synchronization of all the animal were divided into group 1 (n=100), group 2 (n=100), and group 3 (n=100) by applying 600 IU of hCG 6 d after sponge removal, 600 IU of hCG 8 d after sponge removal, and no hCG application (Control), respectively. The difference between groups in terms of reproductive parameters such as estrus, pregnancy, multiple pregnancy, litter size, and productivity was not statistically significant. The live birth weight of lambs was evaluated for singletons, twins, and triplets. The difference between group 1 and the control group was statistically significant in singleton lambs (P=0.04). The difference between group 1 and control (P<0.001) and between group 2 and control (P<0.001) was statistically significant for twins. In triplets, group 1 was different from both groups (P<0.001) and group 2 was different from the control group (P<0.001). In addition, when the placenta weight and the daily body weight gain of singleton lamb in the neonatal stage were examined, the values of both groups that were administered with post mating hCG were higher than the control group (P<0.001). The Progesterone (P4) level in blood samples taken on the 21st d of pregnancy was found to be different between all groups. Furthermore, P4 levels were found to be higher in group 1 compared to the other two groups (P<0.001). In the light of these findings, it was determined that hCG administration after mating contributed to placenta and offspring development by elevating P4 levels. It was concluded that hCG should be administered 6 d after the sponge will be removed (on d 5 postmating) for optimal efficacy.