bluuebunny/crossref_metadata_2025 huggingface dataset:
The diagnostic value of HPV E6/E7 mRNA test in young women with cervical squamous intraepithelial lesion: A Retrospective Analysis
Authors: Wang Jing , Xu Xiaomin
Published: March 2021

Background At present, the HPV DNA test is used to triage young female patients with abnormal cytology. Still, it is not suitable to precisely identify the population with persistent HPV infection. The purpose of this study was to evaluate the diagnostic value of HPV E6/E7 mRNA test in young women with abnormal cytology by comparing HPV DNA test.Methods A total of 258 young women aged 20 to 29 years,with squamous cell abnormalities on the cervical cytology, were enrolled in this study between January 2015 and December 2019.All patients were subject to HPV DNA test, HPV E6/E7mRNA test,colposcopy biopsy, and histopathological examination.A comparative analysis of the diagnostic performance of the HPV DNA test and HPV E6/E7mRNA test was conducted according to the histological diagnosis(CIN II and CIN II+were defined as high-grade squamous intraepithelial lesion+(HSIL+)).Results The results showed that HPV E6/E7 mRNA test had a higher specificity of 47.3%(40.0%-55.1%) for HSIL+ compared to HPV DNA test that had specificity of 16.0% (11.0%-22.6%)in young women(P<0.01). The HPV E6/E7 mRNA test presented high rates of specificity,positive predictive value (PPV), and negative predictive value(NPV), which were 92.1%(86.0%-96.0%), 62.1%(42.4%-78.7%), 92.1%(85.9%-95.8%), respectively, compared to that of HPV DNA,which were 15.8%(10.4%-23.2%),14.6%(9.40%-21.9%), and 71.0%(51.8%-85.1%),respectively(P<0.01)in young women with mildly abnormal cytology(ASC-US and LSIL). Yet, with severe abnormal cytology(ASC-H and HSIL), HR-HPV test was similar to HPV E6/E7 mRNA test in sensitivity(χ2=0.98,P=0.322),specificity(χ2=0.938,P=0.333),PPV(χ2=0.074,P=0.786) and NPV(χ2=0.00,P=1.000).Conclusions Compared to the HPV DNA test,the HPV E6 /E7mRNA test has better clinical value in screening cervical cancer and predicting the risk of HSIL+ in young women, especially those with mild abnormal cytology.
Differences in characteristics between definite vestibular migraines, migraines with vestibular symptoms that do not meet vestibular migraine criteria, and migraines without vestibular symptoms: A cross-sectional study through the lens of central sensitization
Authors: Toriyama Toshihide , Hanaoka Yoshiki , Horiuchi Tetsuyoshi
Published: March 2021

Background: The demographic and clinical characteristics of vestibular migraine (VM) based on the International Classification of Headache Disorders (ICHD)-III beta are not well documented, and the underlying pathophysiology remains largely unknown. Based on evidence that central sensitization is involved in VM pathogenesis, we hypothesized that cutaneous allodynia (CA), which is a clinical manifestation of central sensitization, and interictal widespread pressure hyperalgesia (IWPH), which may be an accelerator for central sensitization, are more frequently associated with VM patients compared with non-VM patients. The aim of this study was as follows: 1) to assess differences in demographic and clinical characteristics among VM patients, patients with migraine with vestibular symptoms not meeting VM criteria (MwVS), and patients with migraine without vestibular symptoms (MwoVS); and 2) to evaluate whether VM patients were more frequently associated with CA/IWPH compared with the other two groups.Methods: This cross-sectional study enrolled consecutive migraine patients, aged 18–65. The comprehensive interview form included diagnostic questions of migraine and VM, demographic characteristics, migraine-specific variables, migraine-associated symptoms, and CA. IWPH occurrence was investigated using a manual tender point survey and clinical parameters were compared.Results: A total of 245 episodic migraineurs (mean age = 39.5 ± 11.3 years, 81.2% women) were enrolled. Based on ICHD-III beta criteria, 65 (26.5%), 74 (30.2%), and 106 (43.3%) patients were assigned to the VM group, MwVS group, or MwoVS group, respectively. Pairwise comparisons demonstrated no significant differences between the VM and MwVS groups, except for higher occurrence of headache disability in the VM group. Compared with the MwoVS group, the VM group was significantly associated with aura, severe disability, depression, tinnitus, sleep disorders, multimodal CA, and IWPH.Conclusions: There were no significant differences in clinical features between VM and MwVS groups, except for disability, which was possibly caused by criteria selection bias. VM and MwVS may be on the same disease process spectrum. Widespread multimodal CA, including clinical manifestations of thalamic sensitization, was significantly associated with VM patients compared with MwoVS patients, which indicates that thalamic sensitization may play a key role VM pathogenesis. Furthermore, IWPH may enhance susceptibility to thalamic sensitization.
MicroRNA-221 Targets FBXW11 to Inhibit NPC Cell Proliferation by Regulating PTEN Signaling
Authors: Liu Jun , Song Chengyi , Liang Zhuoping , Long Xiang , Guo Min , Xu Jianle
Published: March 2021

Background: In the current study, we aim to demonstrate the biological function and molecular regulatory mechanisms of miR-221 in human nasopharyngeal carcinoma (NPC). Methods: The quantitative real time-polymerase chain reaction was used to measure the expression of miR-221 in NPC clinical tissues and cells. And the flow cytometry assay was used to demonstrate the role of miR-221 on cell cycle, and the potential target of miR-221 was predicted and identified using luciferase reporter assay.Results: Our results demonstrate that miR-221 expression was significantly decreased in NPC tissues and cell lines. We also confirmed that inhibition of miR-221 could induce G1/S cell cycle transition through upregulation of the cyclin D-CDK4/6 complex but not cyclin E-CDK2 complexes. Furthermore, luciferase reporter assay demonstrated that miR-221 could directly bind to the 3’-UTR of FBXW11. FBXW11 expression was found to increase in NPC, and was inversely correlated with miR-221 expression; thus, FBXW11 expression interfered in the biological function of miR-221. We further confirmed that miR-221 targeted FBXW11 to inhibit proliferation and promote apoptosis in NPC cell lines through regulating the PTEN signaling pathway. Conclusion: our findings suggest that miR-221 plays an important role as a tumor suppressive factor in the occurrence and progression of NPC.
SARS-CoV-2 Reinfection within the first 3 months of COVID-19 Recovery in A Referral Hospital, Tehran, Iran
Authors: Sadr Sara , Bafrani Melika Arab , Abdollahi Alireza , SeyedAlinaghi SeyedAhmad , Mohammadnejad Esmaeil , Hossienzade Roghieh , Golestan fereshteh Shahmari , Ahmadinejad Zahra , Salehi Mohamadreza , Javaherian Mohammad , Kimyaee Elahe , Jafari Fatemeh , Ghiasvand Fereshteh
Published: March 2021

ObjectivesPossibility of reinfection with SARS-CoV-2 changes our view on herd immunity and vaccination, and can impact quarantine policies. We performed follow-up studies on recovered patients to assess possible development of reinfections.MethodDuring a 6-month period, 202 PCR-confirmed recovering COVID-19 patients entered this study. Follow-up RT-PCR tests and symptoms assessment were performed one month after the initial Positive results. patients who tested negative were tested again one and three months later. The Serum IgG and IgM levels were measured in the last follow-up session.ResultsIn the first two follow-up sessions, 82 (out of 202) and 44 patients participated with four and three asymptomatic patients testing positive. In the last session, 32 patients were tested and four were positive, three of them were mildly symptomatic and all of them were positive for IgG.ConclusionA positive RT-PCR in a recovering patient may represent reinfection. While we did not have the resources to prove reinfection by genetic sequencing of the infective viruses, we believe presence of mild symptoms in the three patients who tested positive over 100 days after becoming asymptomatic, can be diagnosed as reinfection. The IgG may have abated the symptoms of the reinfection, without providing complete protection.
­Trends and Zonal Variability of Extreme Rainfall Events Over East Africa During 1960-2017
Authors: Ojara Moses.A , Lou Yunsheng , Babaousmail Hasssen , Wasswa Peter
Published: March 2021

East African countries (Uganda, Kenya, Tanzania, Rwanda, and Burundi) are prone to weather extreme events. In this regard; the past occurrence of extreme rainfall events is analyzed for 25 stations following the Expert Team on Climate Change Detection and Indices (ETCCDI) regression method. Detrended Fluctuation Analysis (DFA) is used to show the future development of extreme events. Pearson’s correlation analysis is performed to show the relationship of extreme events between different rainfall zones and their association with El Niño -Southern Oscillation (ENSO and Indian Ocean dipole (IOD) IOD-DMI indices. Results revealed that the consecutive wet day's index (CWD) was decreasing trend in 72% of the stations analyzed, moreover consecutive dry days (CDD) index also indicated a positive trend in 44% of the stations analyzed. Heavy rainfall days index (R10mm) showed a positive trend at 52% of the stations and was statistically significant at a few stations. In light of the extremely heavy rainfall days (R25mm) index, 56% of the stations revealed a decreasing trend for the index and statistically significant trend at some stations. Further, a low correlation coefficient of extreme rainfall events in the regions; and between rainfall extreme indices with the atmospheric teleconnection indices (Dipole Mode Index-DMI and Nino 3.4) (r = -0.1 to r = 0.35). Most rainfall zones showed a positive correlation between the R95p index and DMI, while 5/8 of the rainfall zones experienced a negative correlation between Nino 3.4 index and the R95p. In light of the highly variable trends of extremes events, we recommend planning adaptation and mitigation measures that consider the occurrence of such high variability. Measures such as rainwater harvesting, stored and used during needs, planned settlement, and improved drainage systems management supported by accurate climate and weather forecasts is highly advised.
Unpacking the black box of the effectiveness of task forces in maternal and neonatal health in Morocco : A realist evaluation protocol 
Authors: Belrhiti Zakaria , Moulki Rachid , Mowafaq Safwane , Chrifi Hassan , Assarag Bouchra
Published: March 2021

Background In low and middle incomes countries (LMICs), health policies failed to reduce significantly maternal and neonatal mortality rates. This was attributed to inequitable access to care and to poor governance of local health systems. In Morocco, there are still regional disparities with access to maternal care, and poor governance of regional maternal and neonatal health programmes (RMNHP). To address these governance issues, the ministry of health implemented in 2017 a multi-actor’s governance structure called “regional task forces”(RTF). They aim at enabling collective concerted actions, active engagement of local community partners and better coordination between health systems managers and frontline workers in the monitoring, assessment and implementation of RMNHP. In this study, we aimed at analysing how regional taskforces were implemented in six heath regions and identify the mechanisms and contextual conditions underlying their effectiveness.Methods We adopted the realist evaluation as a suitable approach to decipher complex intertwined social phenomena. We adopted a multiple embedded case study design that allows a flexible exploration of different levels of analysis and takes into consideration the role of context. First, we developed an initial programme theory based on a literature review and policy document analysis as follows: ”A taskforce is effective whenever there is a fit between its intrinsic technocratic, political, democratic and learning capacities and the characteristics of the institutional context, the complexity of health problems and the engagement and leadership of actors”. Our programme theory will be refined using 10 to 12 individual interviews (IDI) with policy implementers. We will use secondary documents, and 4 to 6 interviews with taskforces members (clinicians, managers, and midwives). We will then carry two in-depth case studies in one low and one high performing taskforce using additional 6 to 12 interviews, 3 focus group discussions with senior managers, clinicians, and midwives. Qualitative data analysis will be informed by Intervention Context Actor Mechanism Outcome (ICAMO) hypothesis coding. We will then compare the different ICAMOs across cases using qualitative comparative analysis . DiscussionThe resulting programme theory will guide the reinforcement of regional governance of MNH programmes in Morocco.
EVALUASI HUBUNGAN BIAYA INVESTASI TERHADAP KUALITAS KENYAMAN PADA PERUMAHAN
Authors: Ilfiani Pratiwi Dian , Siswosukarto Suprapto , Sulistyo Djoko
Published: March 2021

ABSTRACTThe demand for housing has never stopped because the population growth  always increased. Technical Guidelines for the Construction of Healthy Houses issued by the Minister of Regional Regional Development states that a house as a place of residence must meet indoor health and comfort requirements which is influenced by lighting, airing, air temperature and humidity. This study uses natural lighting, natural ventilation, room humidity and acoustic comfort as variables. The object of this study is limited to the building area of a maximum of 70 m2 with four sample that maintain the original house shape from the design of the developer. Three out of four houses showed the relation between investment and indoor comfort, the higher investment improve indoor comfort. But, one of them showed different pattern, this is because the investment value is influenced by the accessibility of site and buildings.This study found that indoor comfort is influenced by design factors and micro climates. While home investment is influenced by the design and accessibility of site and buildings.Keywords: indoor comfort, lighting, natural ventilation, humidity, acoustic comfort ABSTRAK Tuntutan adanya sebuah rumah tidak pernah berhenti karena pertumbuhan penduduk yang selalu meningkat. Pedoman Teknis Pembangunan Rumah Sederhana Sehat yang dikeluarkan oleh Menteri Permukiman dan Prasarana Wilayah (2002) menyatakan bahwa rumah sebagai tempat tinggal yang memenuhi syarat kesehatan dan kenyamanan dipengaruhi aspek  pencahayaan, penghawaan, serta suhu udara dan kelembaban dalam ruangan. Adapun variabel yang diangkat terdiri dari pencahayaan alami, penghawaan alami, kelembaban ruang dan kebisingan. Objek dari penelitian ini dibatasi pada dengan luas bangunan maksimal 70 m2 dengan empat sampel rumah yang mempertahankan bentuk rumah asli dari desain pengembang. Dari empat rumah, tiga diantara menunjukkan hubungan bahwa semakin tinggi investasi semakin baik kualitas kenyamanan di dalamnya. Akan tetapi satu diantaranya memperlihatkan pola yang berbeda, hal tersebut dikarenakan nilai investasi yang dipengaruhi oleh nilai aksesibilitas lahan dan bangunan. Penelitian ini pada akhirnya mendapatkan hasil bahwa kenyamanan dalam ruang dipengaruhi oleh faktor desain rumah dan iklim mikro. Sedangkan investasi rumah dipengaruhi oleh desain dan nilai aksesibilitas lahan dan bangunan. Kata kunci: kenyamanan dalam ruang, pencahayaan, penghawaan, kelembaban, kebisingan
ANALISIS REGANGAN BAJA TULANGAN PADA STRUKTUR PILE CAP EMPAT TIANG METODE STRUT AND TIE MODEL
Authors: Sukarman Sukarman , Sulistyo Djoko , Irawati Inggar Septhia
Published: March 2021

ABSTRACTPile cap is one of the many types of structures that are entirely Disturbed-region. The structure undergoes a non-linear strain because it was meeting point of the pile and column with centralized forces. In addition, geometry changes occur at the meeting between the column, pile cap, and pile, so the Bernoulli concept is no longer suitable for this condition. Pile cap testing consists of two groups of specimens and each group consists of three specimens. The first group was designed using the STM method (SNI 2847: 2013 Appendix A) and the second group was designed using conventional methods (SNI 2847: 2013 Article 15). Loading is the application of a centralized static load that is channeled through a centric column until the pile cap structure has collapsed. The results show that: (1) The flexural reinforcement which experiences the first yield condition both on the pile cap testing of the STM method and in the conventional method was the X direction flexural reinforcement (outsidest flexural reinforcement). (2) The average strain of the yield conditions and load on the pile cap STM method were 2242 με and 528.97 kN, whereas the conventional method were 2436 με and 437.03 kN. (3) Increasing the load capacity of the yield conditions (Py) of the pile cap STM method and conventional method on the plan load (Pn) were 32.2% and 9.3%.Keywords: pile cap, four piles, Strut and Tie Model (STM)  ABSTRAK Pile cap merupakan salah satu dari jenis struktur yang sepenuhnya merupakan daerah terganggu (Disturbed-region). Struktur tersebut mengalami regangan non-linear karena merupakan titik pertemuan pile dan kolom dengan gaya-gaya terpusat. Selain itu, terjadi perubahan geometri pada pertemuan antara kolom, pile cap, dan pile, sehingga konsep Bernoulli tidak cocok lagi pada kondisi tersebut. Pengujian pile cap terdiri dari dua kelompok benda uji dan masing-masing kelompok terdiri dari tiga buah benda uji. Kelompok pertama dirancang menggunakan metode STM (SNI 2847:2013 Lampiran A) dan kelompok kedua dirancang menggunakan metode konvensional (SNI 2847:2013 Pasal 15). Pembebanan berupa penerapan beban statik terpusat yang disalurkan melalui kolom sentris sampai struktur pile cap mengalami keruntuhan. Hasil menunjukkan bahwa: (1) Tulangan lentur yang mengalami kondisi leleh terlebih dahulu baik pada pengujian benda uji pile cap metode STM maupun pada metode konvensional adalah tulangan lentur arah X (tulangan lentur terluar). (2) Rata-rata regangan kondisi leleh dan beban pada benda uji pile cap metode STM adalah 2242 με dan 528,97 kN, sedangkan pada metode konvensional adalah 2436 με dan 437,03 kN . (3) Peningkatan kapasitas beban kondisi leleh (Py) pada benda uji pile cap metode STM dan metode konvensional terhadap beban rencana (Pn) adalah 32,2 % dan 9,3 %. Kata kunci: pile cap, empat tiang, Strut-and-Tie Model (STM)
PENGARUH BIAYA LIFE CYCLE COST PADA HARGA SEWA KAMAR BUDGET HOTEL DI KOTA YOGYAKARTA (Studi Kasus Hotel Musafira, Hotel Asana Grove, dan Hotel Nagari)
Authors: Dwiyanto Titis , Siswato M. Fauzie , Priyosulistyo Hrc.
Published: March 2021

ABSTRAK Persaingan pasar yang terjadi menyebabkan harga sewa yang ditentukan oleh budget hotel kepada konsumen terbilang rendah. Dengan anggapan bahwa lahan hotel tersebut merupakan lahan sewa, penentuan harga sewa kamar menjadi salah satu keputusan penting karena harga yang ditawarkan harus bisa menutup semua biaya yang dikeluarkan. Kajian ini dilakukan dengan metode wawancara dan analisis data sekunder untuk mendapatkan biaya keseluruhan dari awal hotel dan diprediksi sampai periode 25 tahun dengan metode Future Worth Method, Simple Payback Method dan Discounted Payback Method untuk menentukan harga pokok produksi. Hasil kajian menunjukkan bahwa harga pokok produksi sewa hotel dengan penghitungan life cycle cost lebih tinggi rata - rata 13.31% jika dibandingkan dengan harga sewa kamar hotel yang ditawarkan, oleh karena itu target tingkat hunian hotel per tahun harus ditingkatkan rata – rata sebesar 12.59% untuk menutup selisih kekurangan biaya life cycle cost bangunan budget hotel jika ingin tetap mempertahankan harga sewa yang ditawarkan saat ini. Kata kunci: budget hotel, life cycle cost, harga sewa kamar  ABSTRACTDue to market competition among budget hotel managements the room rate may have gone below rational basis. Assuming that the rent of land area used by the hotel was considered, the price of the room rate may become a significant and important decision, since such a cost shall be able to cope the overall cost including cost of building construction as well as operational and maintenance cost. This research was conducted by interview and by analyzing the secondary data, collected from three budget hotels. The overall cost including planning, designing, construction and maintenance for life period of 25 years was analyzed using Future Worth Method, Simple Payback Method, and Discounted Payback Method in determining the basic production cost. This research concludes that the basic production cost, where life cycle cost is considered, is 13,31% higher than that average room rate as being offered. Therefore, targeted occupancy of the room in the coming years shall be increased by 12,59%, if available room rate is maintained the same.Keywords: budget hotel, life cycle cost, room rate
PRINCIPIOLOGIA DO ECA NO CASO BEBÊ JONATAS E A ACUSAÇÃO DE CRIME PATERNAL: representações sociojurídicas sobre direito da criança e o dever dos pais
Authors: Lopes Ricardo Cortez
Published: March 2021

O caso do bebê Jonatas, criança catarinense portadora de uma doença extremamente agressiva, mobilizou um bom número de doações financeiras, sejam elas em espécie, sejam em gênero. A controvérsia pública se deu por conta de algumas atitudes dos pais da criança após as doações, em que foram adquiridos bens e realizadas viagens. O presente artigo aborda a controvérsia para explicar o modo como a justiça brasileira lidou com o caso: ao não conseguir enquadrar o casal juridicamente através do ECA, tentou proteger a criança e aplacar a condenação pública utilizando o código civil e o código penal, na busca da equidade. A conclusão do estudo é que o ECA tornou válido o direito da criança e o código penal foi mobilizado para lidar com os pais.
Regularity and normality in ideal bitopological spaces
Authors: Pachón Rubiano Néstor Raúl
Published: March 2021

We introduce, and study, the regularity and normality in ideal bitopological spaces, absent subject in literature. Our definitions have the advantage of using only the open sets of the two underlying topologies. These new concepts represent generalizations of Kelly’s concepts of pairwise regularity and pairwise normality. The extension of the T0, T1 and T2 axioms to these spaces is due to Caldas et al.
Evaluation of the Effectiveness and Efficiency of the Government Regulation Implementation Number 12 of 2019
Authors: Icuk Rangga Bawono  , Adhitia Pradana  , Apriani Kartika Rahayu
Published: March 2021

The law should govern the dynamics of the nation and state life in an ideal country. For instance, Indonesia is a constitutional state that subjects to legal supervision based on the 1945 Constitution for state administration. Public policies are used as guidelines and references for actions, including financial management. However, regulations as the basis for regional financial management need to be adjusted to suit the dynamics in legal condition development and the community needs. Government Regulation Number 12 of 2019 is an improvement to Government Regulation Number 58 of 2005 on Regional Financial Management used as a reference in formulating regional financial management rules. This study examines the evaluation of the readiness to implement Government Regulation Number 12 of 2019 as the basis for regional financial management. The method used in this study is a normative legal research method. The legal materials source from primary and secondary legal material. The method in presenting this research result is deductive method. This study shows that financial management is a government responsibility in exercising regional power. The urgency of drafting a Regional Regulation on financial management is motivated by changes in legal dynamics and community needs for its management. Furthermore, there is a need for evaluation of the regulation improvement for effectiveness. In conclusion, the effectiveness and efficiency of regional financial management should be evaluated after Government Regulation Number 12 of 2019 is applied. The regulations need to be disseminated for the wider community response to be identified for evaluation of improvements and adjustments to its needs.
Legal Liability of Doctors on the Disclosure Medical Secrecy for Covid-19 Patients in the Pandemic Era
Authors: Almadani Jaufan Fata , Putera Andika Persada , Yulianto
Published: March 2021

The Covid-19 outbreak is a disease that attack countries around the world, no exception in Indonesia. The discourse of revealing the secrecy of positive Covid-19 patient medicine raises pros and cons in society. This study aims to analyze the concept of medical secrecy according to statutory regulations and legal liability of doctors in revealing medical secrecy in the pandemic era. This study uses a normative juridical method with a statutory approach, and a conceptual approach. The source of data collection consists of primary, secondary, and tertiary legal material. The results of the research show that medical secrecy is confidential individual right. The identity of Covid-19 patients can be accessed in a limited manner by authorized institutions and used proportionally and appropriately for the benefit of handling the Covid-19 outbreak. In order to anticipate an increase in Covid-19 transmission, the practice of using patient personal data is implemented by several countries according to principles proporsionalitas, necesssitas and purposive limitation.
Hubungan Kebiasaan Merokok Masyarakat dengan Pengeluaran Kesehatan Individu di Indonesia: Analisis Survei Kehidupan Keluarga Indonesia 2014/2015
Authors: Fauzia Hana , Kamilah Afifah Nada , Azizah Fizri Nur , Riza Muhammad Rayhan Devan , Zaqi Aditya Maulana , Sihaloho Estro Dariatno
Published: March 2021

ABSTRAK

Kebiasaan merokok merupakan salah satu masalah kesehatan masyarakat yang serius di Indonesia. Pada tahun 2016, Southeast Asia Tobacco Control Alliance (SEATCA) melaporkan terdapat 65,19 juta perokok di Indonesia atau setara dengan 34% dari jumlah penduduk. Penelitian ini bertujuan untuk menganalisis pengaruh kebiasaan merokok terhadap kesehatan individu dan pengeluaran pribadi. Penelitian ini menggunakan metode Ordinary Least Squares (OLS) dengan menggunakan data sekunder dari Indonesian Family Life Survey (IFLS 5) tahun 2014/2015. Hasil penelitian menunjukkan kebiasaan merokok masyarakat meningkat signifikan terkait pengeluaran kesehatan individu. Sedangkan variabel lain seperti jenis kelamin, usia, jumlah rokok yang dikonsumsi dalam satu hari, pendapatan, penyakit kronis, dan wilayah pemukiman (perkotaan atau pedesaan) juga memiliki hubungan positif dengan pengeluaran kesehatan individu.

Kata Kunci: Pengeluaran Kesehatan Individu, Kebiasaan Merokok, Penyakit Kronis, Perkotaan
POTENSI AIR LAUT ACEH SEBAGAI SUMBER ENERGI LISTRIK ALTERNATIF
Authors: Nengsih Sri
Published: March 2021

Keberadaan air laut yang melimpah di Indonesia menjadikannya potensial sebagai sumber energi alternatif  dalam mengatasi keterbatasan pasokan energi untuk jangka panjang. Kajian ini bertujuan untuk mengetahui potensi air laut Aceh sebagai sumber energi alternatif. Proses pengukuran ini menggunakan dua plat elektroda yakni plat lempeng tembaga sebagai elektroda positif dan Plat Lempeng Seng sebagai elektroda negatif. Kedua plat direndamkan dalam wadah yang berisi air laut dan dirangkai secara seri. Volume air laut divariasikan mulai dari 600 ml, 800 ml dan 1000 ml. Sampel air laut diambil dari tiga Lokasi air laut yang berbeda yaitu air laut Ujung Pancu, air laut Kahju dan air laut Alue Naga. Hasil pengukuran menunjukkan bahwa, nilai arus dan tegangan terbesar didapati pada air laut daerah Ujung Pancu kemudian air laut daerah Kahju dan air laut daerah Alue Naga. Daya hantar listrik yang baik ini menunjukkan adanya korelasi dengan tingkat kadar salinitas air laut daerah tersebut. Dapat disimpulkan bahwa air laut Aceh dapat digunakan sebagai salah satu sumber energi alternatif.
Analisa Gangguan Belitan Stator Pada Motor Brushless DC Menggunakan Matlab Simulink
Authors: Kurniawan Didit Lestyo , Diah PK Iradiratu , Yan Dewantara Belly
Published: March 2021

Motor Brushless Direct Current sebagai salah satu mesin listrik yang banyak digunakan di industri, ketika diberi pembebanan maka kecepatan motor akan berubah sehingga fungsi alih motor juga mengalami perubahan. Mekanisme kerusakan pada motor BLDC yang paling umum dapat dikategorikan menurut komponen utama mesin seperti gangguan pada belitan stator, rotor dan bearing. Gangguan pada bagian belitan stator hal ini disebabkan karena hubung singkat belitan stator.Maka pada penelitian ini membahas analisa gangguan pada bagian belitan stator dan dilakukan dalam beberapa variasi kondisi pembebanan dengan menggunakan software Matlab R2013a. Beban yang digunakan adalah  tanpa beban,10 N.m dan 20 N.m Hasil dari data tersebut kemudian diolah menggunakan metode Fast Fourier Transform (FFT) digunakan untuk analisis arus stator dari domain waktu kedalam domain frekuensi. Data analisa berupa karakeristik nilai-nilai arus terhadap frekuensi. Deteksi gangguan belitan stator pada motor BLDC dilakukan dengan mengamati amplitudo pada frekuensi terjadinya gangguan belitan stator yang muncul disekitar frekuensi fundametal. Resolusi frekuensi digunakan untuk mengatur tingkat akurasi pengamatan amplitudo pada spectrum frekuensi. Rata – rata pada persentase tingkat keberhasilan deteksi hubung singkat belitan stator untuk pembebanan dan tanpa beban 94 %. Dampak positif adanya sistem analisa gangguan belitan stator dapat mengantisipasi kerusakan fatal pada motor BLDC.
PENGGUNAAN MEDIA PEMBELAJARAN MIND MAP UNTUK MENINGKATKAN HASIL BELAJAR PESERTA DIDIK PADA MATA PELAJARAN DASAR LISTRIK DAN ELEKTRONIKA DI KELAS X TEKNIK AUDIO VIDIO SMKN 1 SIMPANG ULIM
Authors: Maili Andrika , Kurniawan Hadi , Yasa Ghufram Ibnu
Published: March 2021

Dari hasil observasi awal peserta didik dalam bidang teknik audio vidio pada mata pelajaran Dasar Listrik dan Elektronika di SMKN 1 Simpang Ulim masih terdapat kekurang pada penggunaan media pembelajaran dan masih rendahnya hasil belajar peserta didik yang belum mencapai kriteria (KKM ). Penelitian   inidilakukan dengan tujuan untuk mengetahui hasil belajar peserta didik setelah menggunakan media pembelajaran Mind Map dikelas X Teknik audio vidio SMKN 1 Simpang Ulim. Penerapan media pembelajaranMind Map adalah sebagai proses memetakan pikiran untuk menghubungkan konsep-konsep permasalahan   tertentu dan hasilnya dituangkan langsung   diatas kertas dengan animasi yang disukai dan gampang dimengerti oleh pembuatnya. Metode yang digunakan dalam penelitian ini  adalah metode kuantitatif dengan Quasi-Eksperimen yang merupakan eksperimen semu untuk mengetahui  ada tidaknya akibat dari suatu perlakuan yang dikenakan pada subjek didik.Populasi dalam penelitian ini seluruh peserta didik di SMKN 1 Simpang Ulim dengan jumlah 396 peserta didik, sedangkan sampel yang digunakan seluruh peserta didik di kelas X teknik audio vidio di SMKN 1 Simpang Ulim sebanyak 17 orang. Pengumpulan data mengguankan pretes, perlakuan dan postest. Hasil penelitian menunjukkan bahwa   hasil balajar peserta didik sebelum menggunakan media pembelajaran mind map dengan nilai rata-rata yaitu 29.11 dan setalah diberikan perlakuan dengan menggunakan media pembelajaran nilai rata-rata nya meningkat sebesar 66.47. Analisis  hasil  belajar    diperoleh  thitung>ttabel   (7.33>2.110)  sehingga  H0   ditolak  dan  Ha   diterima. Sehingga dapat disimpulakan bahwa penggunaan media pembelajaran Mind Map pada mata pelajaran Dasar Listrik dan Elektronika di SMKN 1 Simpang Ulim berpengaruh terhadap hasil belajar peserta didik.
Intraspecific genetic variation matters when predicting seagrass distribution under climate change
Authors: Hu Zi-Min , Zhang Quan-Sheng , Zhang Jie , Kass Jamie , Stefano Mammola , Fresia Pablo , Stefano Draisma , Assis Jorge , Jueterbock Alexander , Yokota Masashi , Zhang Zhixin
Published: March 2021

Seagrasses play a vital role in structuring coastal marine ecosystems,
but their distributional range and genetic diversity have declined
rapidly over the past decades. In order to improve conservation of
seagrass species, it is important to predict how climate change may
impact their ranges. Such predictions are typically made with
correlative species distribution models (SDMs), which can estimate a
species’ potential distribution under present and future climatic
scenarios given species’ presence data and climatic predictor variables.
However, these models are typically constructed with species-level data,
and thus ignore intraspecific genetic variability of populations that
potentially have adaptations to heterogeneous climatic conditions. Here,
we explore the link between intraspecific adaptation and niche
differentiation in Thalassia hemprichii, a seagrass broadly distributed
in the tropical Indo-Pacific Ocean and a crucial provider of habitat for
numerous marine species. Using microsatellite-based genotyping, we
identified two distinct phylogeographical lineages within the nominal
species and found an intermediate level of differentiation in their
multidimensional environmental niches, suggesting the possibility for
local adaptation. We then compared projections of the species’ habitat
suitability under climate change scenarios using species-level and
lineage-level SDMs. In the Central Tropical Indo-Pacific region, both
models predicted considerable range contraction in the future, but the
lineage-level model predicted more severe habitat loss. The two
modelling approaches predicted opposite pattern in habitat change in the
Western Tropical Indo-Pacific region. Our results highlight the
necessity of conserving distinct populations and genetic pools under
climate change and have important implications for guiding future
management of seagrasses.
The Brezis-Nirenberg problem for fractional systems with Hardy potentials
Authors: Shen Yansheng
Published: March 2021

In this work we study the existence of positive solutions to the
following fractional elliptic systems with Hardy-type singular
potentials, and coupled by critical homogeneous nonlinearities
\begin{equation*} \begin{cases}
(-\Delta)^{s}u-\mu_{1}\frac{u}{|x|^{2s}}=|u|^{2^{\ast}_{s}-2}u+\frac{\eta\alpha}{2^{\ast}_{s}}|u|^{\alpha-2}
|v|^{\beta}u+\frac{1}{2}Q_{u}(u,v)
\ \ in \
\Omega, \\[2mm]
(-\Delta)^{s}v-\mu_{2}\frac{v}{|x|^{2s}}=|v|^{2^{\ast}_{s}-2}v+\frac{\eta\beta}{2^{\ast}_{s}}|u|^{\alpha}
|v|^{\beta-2}v+\frac{1}{2}Q_{v}(u,v)
\ \ in \
\Omega, \\[2mm]
\ \ u, \ v>0
\ \ \ \
\ in \ \
\Omega, \\[2mm]
\ u=v=0 \ \
\ \ in \ \
\mathbb{R}^{N}\backslash\Omega,
\end{cases} \end{equation*} where
$(-\Delta)^{s}$ denotes the fractional Laplace
operator,
$\Omega\subset\mathbb{R}^{N}$
is a smooth bounded domain such that
$0\in\Omega$,
$\mu_{1}, \mu_{2}\in
[0,\Lambda_{N,s})$,
$\Lambda_{N,s}=2^{2s}\frac{\Gamma^{2}(\frac{N+2s}{4})}{\Gamma^{2}(\frac{N-2s}{4})}$
is the best constant of the fractional Hardy inequality and
$2^{*}_{s}=\frac{2N}{N-2s}$ is the
fractional critical Sobolev exponent. In order to prove the main result,
we establish some refined estimates on the extremal functions of the
fractional Hardy-Sobolev type inequalities and we get the existence of
positive solutions to the systems through variational methods.
Hyperbolicity of the complement of arrangements of non complex lines
Authors: Haggui Fathi , Jalled Abdessami
Published: March 2021

The goal of this paper is twofold. We study holomorphic curves f:C ? C3
avoiding four complex hyperplanes and a real subspace of real dimension five
in C3 where we study the cases where the projection of f into the complex
projective space CP2 is constant. On the other hand, we investigate the
kobayashi hyperbolicity of the complement of five perturbed lines in CP2.
Boundary Schwarz lemma and rigidity property for holomorphic mappings of the unit polydisc in Cn
Authors: Huang Ziyan , Zhao Di , Li Hongyi
Published: March 2021

In this paper, we generalize the classical Schwarz lemma at the boundary from
the unit disk D in the complex plane to the unit polydisc Dn in
higher-dimensional complex space. Two boundary Schwarz lemmas for
holomorphic mappings of Dn and corresponding rigidity properties are
established without the restriction of the interior fixed point.
Stability and convergence analysis for a new class of GNYIP involving XOR-operation in ordered positive Hilbert spaces
Authors: Ahmad Iqbal , Abdullah A , Khedher Khaled , Irfan Syed
Published: March 2021

In the setting of real ordered positive Hilbert spaces, a new class of
general nonlinear ordered Yosida inclusion problem involving ? operation has
been considered and solved by employing a perturbed two step-iterative
algorithm. The stability and convergence analysis of solution of new class
of Yosida inclusion problem involving ? operation has been substantiated by
applying a new resolvent operator and Yosida approximation operator method
with XOR-operation technique. The iterative algorithm and results
demonstrated in this article have witnessed, a significant improvement for
many previously known results of this domain. Further, we give a numerical
example in support of our main result by using MATLprogramming.
Employing Kuratowski measure of non-compactness for positive solutions of system of singular fractional q-differential equations with numerical effects
Authors: Samei Mohammad
Published: March 2021

In this work, we investigate the existence of solutions for the system of two
singular fractional q-differential equations under integral boundary
conditions via the concept of Caputo fractional q-derivative and fractional
Riemann-Liouville type q-integral. Some new existence results are obtained
by applying Krattowski measure of non-compactness. Also, the Darbo?s fixed
point theorem and the Lebesgue dominated convergence theorem are the main
tools in deriving our proofs. Lastly, we present an example illustrating the
primary effects.
Overcoming traps and challenges in child and adolescent psychiatry
Authors: Pejovic-Milovancevic Milica , Grujicic Roberto , Stupar Sanja , Ninkovic Minja
Published: March 2021

Appropriate healthcare and psychological support for children and adolescents is essential for the successful development and good mental health. Unfortunately, this is often a neglected element in the healthcare systems around the world. It is known that approximately half of all adult psychiatric disorders start under the age of 14 and that the prevalence of child and adolescent-onset psychiatric conditions is increasing. The real reason for this increase remains unclear, but it demands our attention as does the care of affected children, adolescents, and their families. Transitions between different age groups need to be made easily navigable for the patients and their families. Many challenges in child and adolescent psychiatry are present, especially in developing countries such as Serbia. A possible solution for overcoming these challenges is uniting the child and adolescent professional societies from all over the world. These societies should work together to develop unified strategies for diagnosis, treatment and support of children affected by psychiatric conditions. By working closely with pediatricians, family physicians, psychologists, nurses, and other professionals, child and adolescent psychiatry can use knowledge and skills to support practice while teaching other professionals how to optimize the utilization of child and adolescent psychiatry services.
Lärarstudenters erfarenheter av två veckors utlandspraktik – en möjlighet till utveckling av interkulturella perspektiv
Authors: Svensson Maria
Published: March 2021

Att öka internationaliseringen inom högre utbildning och speciellt lärarutbildningen har länge varit en viktig fråga. Det handlar vanligen om att studenter ska få möjlighet att skaffa kunskaper om lärande ur ett interkulturellt perspektiv så att de kan verka i ett globaliserat och mångkulturellt samhälle. Det finns forskning som visar vilka effekter internationella utbyten under några månader eller år kan få men det finns få studier av lärarstudenter som genomför kortare internationella utbyten. I denna studie har skriftliga reflektioner i samband med lärarstudenters två veckor långa utlandspraktik i Uganda samlats in för att beskriva de erfarenheter som studenter fått samt hur dessa kan möjliggöra utveckling av interkulturella perspektiv. Genom en kvalitativ innehållsanalys framträder tre teman av erfarenheter som utlandspraktiken har gett upphov till: kulturella, didaktiska och personliga. Den kulturella dissonans som uppstår när studenterna under två veckor får möjlighet att möta en kultur som skiljer sig från den de är vana vid utmanar deras förståelse genom så väl positiva som negativa upplevelser. Även en kortare utlandspraktik med goda möjligheter till reflektion kan bidra till erfarenheter viktiga för att utveckla kunskaper så att de kan verka i ett globaliserat och mångkulturellt samhälle.
INFLUENCE OF INFLATION, BI RATE AND THE RATIO OF THE RESULTS TO THE GATHERING OF THIRD PARTY FUNDS ON SHARIA BANKING IN INDONESIA
Authors: Muhammadinah Muhammadinah
Published: March 2021

This research aims to determine the influence of inflation, BI rate and the ratio of the outcome to third party funding. The population in this study is all sharia banking operating in Indonesia. The sample in this study is the sharia banking statistic report by Bank Indonesia amounting to 36 taken from the number of January 2017 – December 2019. The analytical techniques used in this study are multiple regression analyses with hypothesized tests using the T test and F test, then coupled with the test coefficient of correlation (test R) and test coefficient of determination (R2 test). The results showed that the inflation variable, the BI rate and the yield share ratio jointly impacted significantly to third party funding. Then in partial only variable inflation and BI rate are significant effect on third party funding.
PREDISPOSISI KRIMINAL TINDAK PIDANA PERZINAHAN DAN ABORSI DALAM PELAKSANAAN PERATURAN PEMERINTAH NOMOR 61 TAHUN 2014 TENTANG KESEHATAN REPRODUKSI.
Authors: Fatimah Siti
Published: March 2021

This paper contains a discussion of predisposition or contradiction in laws and regulations governing the crime of adultery with the implementation of abortion. Adultery and abortion are criminal acts that are victimless in nature or crimes with mutual agreement and without victims. In positive Indonesian law, adultery is only considered a criminal act when one or both of the perpetrators are married people or in our society it is known as an affair or gathering. kebo. This is very contrary to Islamic law and laws that live in society or customary law as stated in the Pancasila. As a result, a pregnancy outside of wedlock or an unwanted pregnancy may result from this adulterous relationship. When a pregnancy outside of marriage occurs, the psychological condition of both parties is disturbed and eventually not a few decide to take the path of abortion, especially teenagers, even though at the risk of losing their life. Even though by law abortion is allowed, but even then it must be subject to rules, conditions and supervision. strictly carried out by competent parties as designated by law. The formulation of the article on adultery in Indonesian legislation is still unclear, especially for the act of adultery committed by two men and women who are neither married to any party. However, sexual behavior is risky or between other pre-marital sexual behavior according to Article 11 of Government Regulation no. 61 of 2014 concerning Reproductive Health to prevent and protect adolescents from these acts because it is clear that they have a bad impact both physically and psychologically. This is where there is a conflict between Indonesia's positive law, namely between Article 284 of the Criminal Code and Article 11 of Government Regulation no. 61 of 2014 concerning Reproductive Health. Meanwhile, the adultery article as mentioned above has been clearly stated in Article 240 of the Draft Criminal Code, but so it has not been ratified for certain reasons. Among the efforts to prevent the crime of adultery and abortion is the enforcement of the substance, structure and culture of law in Indonesia.
Fraseología en el lenguaje jurídico: Binomios y multinomios a través del código penal y código civil italiano y español
Authors: González Vallejo Rubén
Published: March 2021

En el presente artículo trataremos las unidades fraseológicas en el lenguaje jurídico con el fin de aportar una profunda contribución a la contrastiva lingüística entre el español y el italiano. Si bien existen estudios recientes (Corpas Pastor, 2003; Higueras García, 2006; Timofeeva, 2012; Leal Riol 2013) sobre la aplicación de la fraseología en ciertos campos de la lingüística aplicada, como la enseñanza de segundas lenguas o la traducción, tradicionalmente se ha detectado una escasez contrastiva en la comparación jurídica de dichas unidades en los idiomas que nos competen. A tal propósito, inicialmente expondremos una de las clasificaciones más aceptadas de la fraseología para luego introducir cuáles son las unidades más presentes en la fraseología especializada en el campo del Derecho. Posteriormente, centraremos nuestra atención en los binomios y multinomios, proporcionando siempre en cada caso diversos ejemplos extraídos del Código Penal y del Código Civil italiano y español a través de la herramienta terminológica AntConc.
Skönlitteraturens språk
Authors: Dahl Christoffer , Smedberg Bondesson Anna
Published: March 2021

This article explores the possibilities of combining literary and linguistic text analyses: a double perspective on the teacher education for secondary school. The aim is to analyze how two students, in a course in text analysis, solve an examination assignment where they are asked to combine literary and linguistic tools in their analysis of Pär Lagerkvist's short story "Father and I" (1924).  We ask the following questions: How do students use literary and linguistic tools in the analysis of Lagerkvist's work and how do they combine these tools? What kind of didactic potentials do students see in a double perspective? The result shows both similarities and differences in how the students combine linguistic and literary tools and how they underpin the analysis. The students’ meta-reflections indicate that such double perspective provides a deeper understanding of literary texts containing both literary and linguistic resources. Our conclusion is that the double perspective may provide a powerful theoretical and didactic tool for students of the Swedish language at the teacher education for secondary school.
ANAK PESISIR BELAJAR IPA (STUDI ETNOGRAFI ATAS POTENSI DAN HAMBATAN KULTURAL ANAK SUMENEP BELAJAR IPA)
Authors: Habibi Habibi , Fajarianingtyas Dyah Ayu
Published: March 2021

Penelitian ini bertujuan untuk mengeksplorasi bagaimana kondisi budaya di kabupaten sumenep yang dapat memberikan dukungan atau hambatan terhadap proses belajar anak pesisir dalam bidang IPA. Jenis penelitian ini adalah kualitatif etnografis, dimana data diperoleh melalui dua teknik yaitu Observasi dan Wawancara. Peneliti dibantu oleh informan kunci (key informant), diambil dari anggota asli masyarakat yang menjadi obyek penelitian. Hasil dari penelitian ini menunjukkan bahwa kehidupan anak pesisir di Sumenep membentuk suatu pola aktivitas yang sesuai dengan ritme profesi orang tuanya. Dalam hal ini umumnya adalah sebagai petani garam, nelayan, peternak atau petani tembakau). Porsi aktivitas belajar anak pesisir (dalam hal ini belajar IPA) masih minim. Umumnya belajar di rumah baru dilakukan ketika anak-anak mendapat tugas (PR) dari gurunya. Kata kunci: Anak pesisir, Belajar IPA, Etnografi.