bluuebunny/crossref_metadata_2025 huggingface dataset:
A Novel Hybrid Model for Predicting Blast-Induced Ground Vibration Based on k-Nearest Neighbors and Particle Swarm Optimization
Authors: Bui Xuan-Nam , Jaroonpattanapong Pirat , Nguyen Hoang , Tran Quang-Hieu , Long Nguyen Quoc
Published: September 2019

In this scientific report, a new technique of artificial intelligence which is based on k-nearest neighbors (KNN) and particle swarm optimization (PSO), named as PSO-KNN, was developed and proposed for estimating blast-induced ground vibration (PPV). In the proposed PSO-KNN, the hyper-parameters of the KNN were searched and optimized by the PSO. Accordingly, three forms of kernel function of the KNN were used, Quartic (Q), Tri weight (T), and Cosine (C), which result in three models and abbreviated as PSO-KNN-Q, PSO-KNN-T, and PSO-KNN-C models. The valid of the proposed models was surveyed through comparing with those of benchmarks, random forest (RF), support vector regression (SVR), and an empirical technique. A total of 152 blasting events were recorded and analyzed for this aim. Herein, maximum explosive per blast delay (W) and the distance of PPV measurement (R), were used as the two input parameters for predicting PPV. RMSE, R2, and MAE were utilized as performance indicators for evaluating the models’ accuracy. The outcomes instruct that the PSO algorithm significantly improved the efficiency of the PSO-KNN-Q, PSO-KNN-T, and PSO-KNN-C models. Compared to the three benchmarks models (i.e., RF, SVR, and empirical), the PSO-KNN-T model (RMSE = 0.797, R2 = 0.977, and MAE = 0.385) performed better; therefore, it can be introduced as a powerful tool, which can be used in practical blasting for reducing unwanted elements induced by PPV in surface mines.
A multilocus sequence typing scheme of Pseudomonas putida for clinical and environmental isolates
Authors: Ogura Kohei , Shimada Kayo , Miyoshi-Akiyama Tohru
Published: September 2019

Pseudomonas putida is a bacterium commonly found in soils, water and plants. Although P. putida group strains are considered to have low virulence, several nosocomial isolates with carbapenem- or multidrug-resistance have recently been reported. In the present study, we developed a multilocus sequence typing (MLST) scheme for P. putida. MLST loci and primers were selected and designed using the genomic information of 86 clinical isolates sequenced in this study as well as the sequences of 20 isolates previously reported. The genomes were categorised into 68 sequence types (STs). Significant linkage disequilibrium was detected for the 68 STs, indicating that the P. putida isolates are clonal. The MLST tree was similar to the haplotype network tree based on single nucleotide morphisms, demonstrating that our MLST scheme reflects the genetic diversity of P. putida group isolated from both clinical and environmental sites.
Design and Demonstration of High-Efficiency Quantum Well Solar Cells Employing Thin Strained Superlattices
Authors: Welser Roger E. , Polly Stephen J. , Kacharia Mitsul , Fedorenko Anastasiia , Sood Ashok K. , Hubbard Seth M.
Published: September 2019

Nanostructured quantum well and quantum dot III–V solar cells provide a pathway to implement advanced single-junction photovoltaic device designs that can capture energy typically lost in traditional solar cells. To realize such high-efficiency single-junction devices, nanostructured device designs must be developed that maximize the open circuit voltage by minimizing both non-radiative and radiative components of the diode dark current. In this work, a study of the impact of barrier thickness in strained multiple quantum well solar cell structures suggests that apparent radiative efficiency is suppressed, and the collection efficiency is enhanced, at a quantum well barrier thickness of 4 nm or less. The observed changes in measured infrared external quantum efficiency and relative luminescence intensity in these thin barrier structures is attributed to increased wavefunction coupling and enhanced carrier transport across the quantum well region typically associated with the formation of a superlattice under a built-in field. In describing these effects, a high efficiency (>26% AM1.5) single-junction quantum well solar cell is demonstrated in a device structure employing both a strained superlattice and a heterojunction emitter.
Responses of primary osteoblasts and osteoclasts from hemizygous β-globin knockout thalassemic mice with elevated plasma glucose to 1,25-dihydroxyvitamin D3
Authors: Charoenphandhu Narattaphol , Aeimlapa Ratchaneevan , Sooksawanwit Supagarn , Thongbunchoo Jirawan , Teerapornpuntakit Jarinthorn , Svasti Saovaros , Wongdee Kannikar
Published: September 2019

β-thalassemia is often associated with hyperglycemia, osteoporosis and increased fracture risk. However, the underlying mechanisms of the thalassemia-associated bone loss remain unclear. It might result from abnormal activities of osteoblasts and osteoclasts, and perhaps prolonged exposure to high extracellular glucose. Herein, we determined the rate of duodenal calcium transport in hemizygous β-globin knockout thalassemic (BKO) mice. Their bones were collected for primary osteoblast and osteoclast culture. We found that BKO mice had lower calcium absorption than their wild-type (WT) littermates. Osteoblasts from BKO mice showed aberrant expression of osteoblast-specific genes, e.g., Runx2, alkaline phosphatase and osteocalcin, which could be partially restored by 1,25(OH)2D3 treatment. However, the mRNA expression levels of RANK, calcitonin receptor (Calcr), c-Fos, NFATc1, cathepsin K and DMT1 were similar in both BKO and WT groups. Exposure to high extracellular glucose modestly but significantly affected the expression of osteoclast-specific markers in WT osteoclasts with no significant effect on osteoblast-specific genes in WT osteoblasts. Thus, high glucose alone was unable to convert WT bone cells to BKO-like bone cells. In conclusion, the impaired calcium absorption and mutation-related aberrant bone cell function rather than exposure to high blood glucose were likely to be the principal causes of thalassemic bone loss.
Multiple introductions and secondary dispersion of Tubastraea spp. in the Southwestern Atlantic
Authors: Capel K. C. C. , Creed J. , Kitahara M. V. , Chen C. A. , Zilberberg C.
Published: September 2019

Accidental introduction through ballast water and biofouling are currently the main factors responsible for spreading non-indigenous species in the marine realm. In the Southwestern Atlantic, two scleractinian corals,Tubastraea coccineaandT. tagusensis, have been introduced by opportunistic colonization in 1980 and are now widespread along more than 3,500 km of coastline. To better understand the invasion process and the role of vectors in spreading these species, we sampled 306 and 173 colonies ofT. coccineaandT. tagusensisfrom invaded sites, possible vectors and one native population. Analyses revealed a higher diversity of multi-locus genotypes (MLGs) on vectors, suggesting that they were contaminated prior to their arrival in the Southwestern Atlantic, and a high proportion of clones at invaded sites, with few genotypes spread over ~2,000 km. This broad distribution is most likely a result of secondary introductions through the transport of contaminated vectors. Results also suggest the occurrence of multiple invasions, mainly in the northernmost sites. In summary, clonality, secondary introductions, and multiple invasions are the main reasons for the broad spread and invasive success ofTubastraeaspp. in the Southwestern Atlantic. Consequently, the correct control of vectors is the most effective approach for management and prevention of new invasions.
Nuclear Chaperone ASF1 is Required for Gametogenesis in Arabidopsis thaliana
Authors: Min Yunsook , Frost Jennifer M. , Choi Yeonhee
Published: September 2019

Sexual reproduction in flowering plants is distinct from that in animals since gametogenesis requires production of haploid spores, which divide and differentiate into specialised gametophyte structures. Anti-Silencing Function 1 (ASF1) is a histone H3/H4 chaperone involved in chromatin remodeling during cell division, which we have found plays a critical role in gametophyte development in Arabidopsis thaliana. Using mutant alleles for the two ASF1 homologs, asf1a and asf1b, we show that ASF1 is required for successful development of gametophytes and acquisition of fertilisation competency. On the female side, reproductive failure is caused by aberrant development of ovules, leading to gamete degeneration. On the male side, we show both in vitro and in vivo that asf1 mutant pollen tube growth is stunted, limiting fertilisation to ovules nearest the stigma. Consistent with ASF1 importance in gametogenesis, we show that ASF1A and ASF1B are expressed throughout female and male gametogenesis. We show that the gametogenesis defects can be corrected by ASF1A and ASF1B transgenes, and that ASF1A and ASF1B act redundantly. Thus, in contrast to the role of ASF1 in sporophytic cell cycle progression, our data indicate that during reproduction, ASF1 is required for the precise nuclei differentiation necessary for gametophyte maturation and fertilisation.
Transmission dynamics of HIV-1 subtype B strains in Indonesia
Authors: Ueda Shuhei , Witaningrum Adiana Mutamsari , Khairunisa Siti Qamariyah , Kotaki Tomohiro , Motomura Kazushi , Nasronudin  , Kameoka Masanori
Published: September 2019

Human immunodeficiency virus type 1 (HIV-1) and acquired immunodeficiency syndrome (AIDS) represent a major public health concern in Indonesia. Although circulating recombinant form (CRF) 01_AE is a predominant subtype in Indonesia, HIV-1 subtype B (HIV-1B) is also widely prevalent. However, the viral genetic evolution, spatial origins, and patterns of transmission of HIV-1B in Indonesia remain unclear. In the present study, we described the evolutionary characteristics and spatial-temporal transmission networks of HIV-1B in Indonesia. To elucidate the epidemiological link between HIV-1B epidemics in Indonesia and those in the remainder of the world, we conducted phylogenetic analyses of HIV-1B strains in Indonesia. Based on the results obtained, at least three epidemic clades [the Indonesia, United States (US), and China clades] of HIV-1B were found to be prevalent in Indonesia. In order to identify the potential source and transmission route of Indonesian HIV-1B strains, we performed Bayesian analyses and constructed Maximum clade credibility trees of each clade. Although some HIV-1B strains in Indonesia were introduced from Thailand, the prevalent HIV-1B strains appeared to have been directly introduced from Europe or America. Indonesian HIV-1B may have spread via the main dispersal of pandemic HIV-1B strains via the US from the Caribbean region rather than being directly introduced from Africa.
Improved Osseointegration of a TiNbSn Alloy with a Low Young’s Modulus Treated with Anodic Oxidation
Authors: Kunii Tomonori , Mori Yu , Tanaka Hidetatsu , Kogure Atsushi , Kamimura Masayuki , Mori Naoko , Hanada Shuji , Masahashi Naoya , Itoi Eiji
Published: September 2019

Ti6Al4V alloy orthopedic implants are widely used as Ti6Al4V alloy is a biocompatible material and resistant to corrosion. However, Ti6Al4V alloy has higher Young’s modulus compared with human bone. The difference of elastic modulus between bone and titanium alloy may evoke clinical problems because of stress shielding. To resolve this, we previously developed a TiNbSn alloy offering low Young’s modulus and improved biocompatibility. In the present study, the effects of sulfuric acid anodic oxidation on the osseointegration of TiNbSn alloy were assessed. The apatite formation was evaluated with Scanning electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy and transmission electron microscopy analyses. The biocompatibility of TiNbSN alloy was evaluated in experimental animal models using pull-out tests and quantitative histological analyses. The results of the surface analyses indicated that sulfuric anodic oxidation induced abundant superficial apatite formation of the TiNbSn alloy disks and rods, with a 5.1-µm-thick oxide layer and submicron-sized pores. In vivo, treated rods showed increased mature lamellar bone formation and higher failure loads compared with untreated rods. Overall, our findings indicate that anodic oxidation with sulfuric acid may help to improve the biocompatibility of TiNbSn alloys for osseointegration.
Pressure-induced tuning of lattice distortion in a high-entropy oxide
Authors: Cheng Benyuan , Lou Hongbo , Sarkar Abhishek , Zeng Zhidan , Zhang Fei , Chen Xiehang , Tan Lijie , Prakapenka Vitali , Greenberg Eran , Wen Jianguo , Djenadic Ruzica , Hahn Horst , Zeng Qiaoshi
Published: September 2019

As a new class of multi-principal component oxides with high chemical disorder, high-entropy oxides (HEOs) have attracted much attention. The stability and tunability of their structure and properties are of great interest and importance, but remain unclear. By using in situ synchrotron radiation X-ray diffraction, Raman spectroscopy, ultraviolet–visible absorption spectroscopy, and ex situ high-resolution transmission electron microscopy, here we show the existence of lattice distortion in the crystalline (Ce0.2La0.2Pr0.2Sm0.2Y0.2)O2−δ HEO according to the deviation of bond angles from the ideal values, and discover a pressure-induced continuous tuning of lattice distortion (bond angles) and band gap. As continuous bending of bond angles, pressure eventually induces breakdown of the long-range connectivity of lattice and causes amorphization. The amorphous state can be partially recovered upon decompression, forming glass–nanoceramic composite HEO. These results reveal the unexpected flexibility of the structure and properties of HEOs, which could promote the fundamental understanding and applications of HEOs.
A low-cost microplasma generation unit allowing for the on-site processing of ZnO-based gas sensors
Authors: Huang Fei-Hung , Lin Sz-Yun , Hsu Cheng-Che
Published: September 2019

In this study, a low-cost gas-sensing device that integrates a zinc-oxide (ZnO)-based gas sensor with a microplasma generation unit is presented.
Establishment of an immunofiltration strip for the detection of 17β-estradiol based on the photothermal effect of black phosphorescence
Authors: Lu Lixia , Wang Minglu , Zhang Dan , Zhang Hongyan
Published: September 2019

In this study, a novel immunofiltration strip method with temperature as the readout signal based on the photothermal effect of black phosphorus nanosheets was established. The temperature was monitored by a portable temperature sensor.
Cascaded multiple recycling amplifications for aptamer-based ultrasensitive fluorescence detection of protein biomarkers
Authors: Qin Yao , Li Daxiu , Yuan Ruo , Xiang Yun
Published: September 2019

Target-induced cascaded multiple recycling amplifications lead to aptamer-based and highly sensitive fluorescence detection of mucin 1.
Efficient photoacoustic imaging using indocyanine green (ICG) loaded functionalized mesoporous silica nanoparticles
Authors: Chaudhary Zanib , Khan Gul Majid , Abeer Muhammad Mustafa , Pujara Naisarg , Wan-Chi Tse Brian , McGuckin Michael A. , Popat Amirali , Kumeria Tushar
Published: September 2019

Herein, we demonstrate the role of surface modification of nanocarriers on their ability to load and protect sensitive payloads.
Single photon DNA photocleavage at 830 nm by quinoline dicarbocyanine dyes
Authors: Basnet Kanchan , Fatemipouya Tayebeh , St. Lorenz Anna , Nguyen Mindy , Taratula Oleh , Henary Maged , Grant Kathryn B.
Published: September 2019

Near-infrared DNA strand scission occurs at pH 7.0 and 10 to 22 °C.
Coordination-induced conformation diversity for pharmaceutical polymorph control
Authors: Kang Juan , Wang Yongli , Chen Yifu , Huang Xin , Yin Qiuxiang , Wang Na , Hao Hongxun
Published: September 2019

Template-induced heteronucleation can dramatically influence crystal polymorphism.
Low-dimensional functional networks of cage-like B40 with effective transition-metal intercalations
Authors: Zan Wen-Yan , Li Hai-Ru , Mu Yue-Wen , Lu Hai-Gang , Li Si-Dian
Published: September 2019

MnB40 networks.
Molecular dynamics investigation of reduced ethylene carbonate aggregation at the onset of solid electrolyte interphase formation
Authors: Boyer Mathew J. , Hwang Gyeong S.
Published: September 2019

Concentration dependent aggregation of reduced ethylene carbonate through Li+ mediation allows for radical combination reactions between the reactive intermediates to stable products such as ethylene dicarbonate.
Enhancement mechanism of Sn on the catalytic performance of Cu/KIT-6 during the catalytic combustion of chlorobenzene
Authors: He Fei , Jiao Yumiao , Wu Liyao , Chen Xi , Liu Shantang
Published: September 2019

Sn promoted the redox capacity of Cu2+ and Sn4+, thus greatly reducing the surface chloride-deposition during the chlorobenzene catalytic combustion process.
Highly crystalline lithium chloride-intercalated graphitic carbon nitride hollow nanotubes for effective lead removal
Authors: Zhou Ying , Liao Changzhong , Fan Yiang , Ma Shengshou , Su Minhua , Zhou Zhengyuan , Chan Ting-Shan , Lu Ying-Rui , Shih Kaimin
Published: September 2019

The intercalation of chloride in the interstitial space of highly crystalline graphitic carbon nitride provides effective binding sites for Pb(ii).
A diet containing high- versus low-daidzein does not affect bone density and osteogenic gene expression in the obese Zucker rat model
Authors: Rochester Eric , Wickman Brooke E. , Bell Andrea , Simecka Christy , Clayton Zachary S. , Hakkak Reza , Hooshmand Shirin
Published: September 2019

Phytoestrogens are nonsteroidal plant compounds with similar chemical structures to mammalian estrogen capable of mimicking the effect of estrogen in selective tissues.
Framing technology challenges associated with improving cancer immunotherapies
Authors: Heath James R.
Published: September 2019

Thought leader Jim Heath introduces the Lab on a Chip Immunotherapy thematic collection.
Macromolecular design strategies toward tailoring free volume in glassy polymers for high performance gas separation membranes
Authors: Corrado Tanner , Guo Ruilan
Published: September 2019

This review highlights recently reported novel macromolecular design strategies providing tailorable free volume for high performance gas separation membranes.
Horizons Community Board Collection – Progress and Development in Advanced Energy Storage Technologies
Authors: Kumar Vipin , Zhu Kai
Published: September 2019

A themed collection on progress and development in advance energy storage technologies, guest edited by Materials Horizons Community Board members Vipin Kumar and Kai Zhang.
Bimetallic MOF-derived porous CoNi/C nanocomposites with ultra-wide band microwave absorption properties
Authors: Liu Chang , Qiao Jing , Zhang Xue , Xu Dongmei , Wu Nannan , Lv Longfei , Liu Wei , Liu Jiurong
Published: September 2019

The CoNi bimetallic MOF-derived composites were synthesized in this work. The target product is composed of fine particles with uniformly distributed elements of Ni, Co, C. The CoNi/C-650 sample displays good microwave absorbing properties.
Multifunctional fluorescent leucomalachite green derivatives for chemodosimetric detection of Fe3+, specific imaging of lipid droplets and intracellular pH monitoring
Authors: Divya Thekke Thattariyil , Raghav Darpan , Rathinasamy Krishnan , Chakkumkumarath Lakshmi
Published: September 2019

Fluorescent leucomalachite green derivatives detect micromolar concentrations of Fe3+, specifically stain lipid droplets in live cells and monitor intracellular pH variations in microorganisms.
Direct measurement of Lighthill's energetic efficiency of a minimal magnetic microswimmer
Authors: Calero Carles , García-Torres José , Ortiz-Ambriz Antonio , Sagués Francesc , Pagonabarraga Ignacio , Tierno Pietro
Published: September 2019

This work demonstrates the direct measurement of the Lighthill's energetic efficiency from a minimal colloid-nanorod magnetic microswimmer.
A self-assembled, nacre-mimetic, nano-laminar structure as a superior charge dissipation coating on insulators for HVDC gas-insulated systems
Authors: Zhang Boya , Wang Qiang , Zhang Yunxiao , Gao Wenqiang , Hou Yicen , Zhang Guixin
Published: September 2019

By mimicking the layered structure of nacre, we successfully fabricated a nano-laminar coating on high-voltage insulators. The coating is demonstrated to achieve a higher flashover strength by effectively dissipating surface charge under dc stress.
Synthesis and supramolecular assembly of fluorinated biogenic amine recognition host polymers
Authors: Kovács Ervin , Deme János , Turczel Gábor , Nagy Tibor , Farkas Vajk , Trif László , Kéki Sándor , Huszthy Péter , Tuba Robert
Published: September 2019

Fluorine functionalized biogenic amine carrier polymers.
First phosphorus AB2monomer for flame-retardant hyperbranched polyphosphoesters: AB2vs. A2+ B3
Authors: Markwart Jens C. , Battig Alexander , Kuckhoff Thomas , Schartel Bernhard , Wurm Frederik R.
Published: September 2019

Hyperbranched polyphosphoesters (hbPPEs) are promising flame retardants. Herein we synthesized the first phosphorus-based AB2monomer for the synthesis ofhbPPEs and assess its flame-retardant performance in an epoxy resin.
Assembling features of calixarene-based amphiphiles and supra-amphiphiles
Authors: Tian Han-Wen , Liu Yan-Cen , Guo Dong-Sheng
Published: September 2019

A systematic review of current achievements in calixarene-based amphiphiles and supra-amphiphiles, mainly focused on their assembling features.
A porous reduced graphene oxide/chitosan-based nanocarrier as a delivery system of doxorubicin
Authors: Hazhir N. , Chekin F. , Raoof J. B. , Fathi Sh.
Published: September 2019

Nowadays, the concept of drug transmission is an important topic in the field of drug delivery research.
Synthesis and electrochemical performances of Na3V2(PO4)2F3/C composites as cathode materials for sodium ion batteries
Authors: Wang Mingxue , Huang Xiaobing , Wang Haiyan , Zhou Tao , Xie Huasheng , Ren Yurong
Published: September 2019

Na3V2(PO4)2F3/C composites were synthesized by a solid-state reaction method using pitch as the carbon source, the as-prepared sample with the carbon content of 12.14% possesses an excellent rate performance and cycle stability.
Recent progress in development of 2,3-diaminomaleonitrile (DAMN) based chemosensors for sensing of ionic and reactive oxygen species
Authors: Aruna Aruna , Rani Bhawna , Swami Suman , Agarwala Arunava , Behera Debasis , Shrivastava Rahul
Published: September 2019

2,3-Diamniomaleonitrile (DAMN) is valuable π-conjugated organic scaffold molecule for designing of efficient chemosensors for sensing of ionic and Reactive Oxygen Species (ROS).
Accumulation risk and sources of heavy metals in supratidal wetlands along the west coast of the Bohai Sea
Authors: Liu Fude , Zheng Bowen , Zheng Yi , Mo Xue , Li Desheng
Published: September 2019

The accumulation risk and sources for heavy metals Al, Cr, Cu, Ni, Pb, Zn, Fe, Mn, As, and Cd were analysed in rainfall-driven supratidal wetlands.
DNA photo-cross-linking using a pyranocarbazole-modified oligodeoxynucleotide with a d-threoninol linker
Authors: Fujimoto Kenzo , Yamaguchi Tsubasa , Inatsugi Takahiro , Takamura Masahiko , Ishimaru Isao , Koto Ayako , Nakamura Shigetaka
Published: September 2019

An alternative more efficient photo-cross-linker having a d-threoninol skeleton instead of the 2′-deoxyribose backbone in pyranocarbazole was investigated to improve the photoreactivity of photo-cross-linkers.
Merging hypervalent iodine and sulfoximine chemistry: a new electrophilic trifluoromethylation reagent
Authors: Kalim Jorna , Duhail Thibaut , Le Thanh-Nghi , Vanthuyne Nicolas , Anselmi Elsa , Togni Antonio , Magnier Emmanuel
Published: September 2019

Two prominent trifluoromethylation reagent classes join forces in a bench stable hypervalent iodosulfoximine CF3transfer agent. We report its synthesis, properties and reactivity, opening up new possibilities in trifluoromethylation chemistry.
Controllable synthesis of barnyardgrass-like CuO/Cu2O heterostructure nanowires for highly sensitive non-enzymatic glucose sensors
Authors: Zhou Qing-Qing , Zhuo Ming-Peng , Chen Rui , Wang Shao-Zhen , Wang Zuo-Shan , Zheng Min , Liao Liang-Sheng
Published: September 2019

Barnyardgrass-like CuO/Cu2O heterostructure nanowires were rationally constructed via a synergistic approach integrating precipitation and microwave process based on porous Cu(OH)2 nanorods and exhibit commendable glucose detection capacity.
Circular patterns of waste prevention and recovery
Authors: Ghisellini Patrizia , Santagata Remo , Zucaro Amalia , Ulgiat Sergio
Published: September 2019

The growth of modern societies with their scientific, economic and social achievements was made possible by the cheap availability of fossil fuels. Side effects of fossil energy resources were the development of unsustainable production and consumption patterns, the degradation of natural capital, and the release of airborne, waterborne and solid waste. Consumption and environmental loading are not only related to fuels, but also to other material resources, such as minerals in general and rare earths in particular. The increasing shortage of crucial resources affects and constrains important economic sectors (e.g., electronic sectors, renewable energies, food production), thus placing a limit on further development and wellbeing. Concepts of sustainable economies and communities, with focus on the social dimension of development and also on the ecological and economic aspects at the same time, are gaining the attention of policy makers, managers, and investors, as well as local stakeholders (organisations, small and medium enterprises, individual citizens) and encouraging new development and business models globally referred to as the “circular economy”. The circular economy (CE) is a production and consumption system that is restorative by intention and design. Although there has been a relative decoupling of economic growth from resource use in recent decades, the gains made so far have been eaten up by a combination of economic growth and the rebound effect. There are two questions: (i) why has it been so hard to move from theory(most often from rhetoric) to practice and implementation, and (ii) how is it possible to promote an innovative and effective CE strategy in urban systems where 60% of world population is concentrated. This shift (design, networking, organisation, implementation, community planning) and related monitoring tools constitute the skeletonof the transition that needs to occur within both urban systems and economies. The point we make is that a society without waste is not only desirable, but also possible and necessary. We cannot wait longer and we cannot just accept small adjustments, increased end-of-pipe technologies and the usual interplay of promises and conflicts. The time for a massive and successful effort towards a radical change of lifestyles and production/consumptionpatterns is now, where the term "waste" itself is considered a symptom of societal illness, an indicator of immature economies, poor science and old-fashioned technology.
Present and prospective role of the oceans and ice cover in the world climate
Authors: Wadham Peter
Published: September 2019

In this article I will focus on the role of the ice-covered oceans, particularly the Arctic, because global warming affects the Arctic more than any other part of the world, and the decline in ice extent which this induces has serious feedback effects upon the enire global climate, including that of the non-polar oceans.
Fostering collective effort toward ecosystem conservation
Authors: Amel Elise , Manning Christie
Published: September 2019

For human society to thrive amidst our changing environmental realities, we must alter our behavior. Individual change, while important, is unreliable due to cognitive and social barriers. An important nexus for the required transformation is at the collective level. Rather than encouraging individuals to engage in personal climate-friendly behavior, our efforts must focus on individuals changing their social networks, engaging in political change, and transforming the organizations in their community, such as corporations, NGOs, boards, and governments. Formal and informal leaders make daily decisions which influence the organizational structures that propel large-scale human behavior change. This scale of change is more in line with the scope needed to successfully persist into the future on this planet.
Waste 4.0. Perceptual alterations of space and time
Authors: Cuozzo Gianluca
Published: September 2019

Living in today’s disfigured environment, where nature is but a fragment of an ancient beauty and richness, means living in a global allegory, where humans are forced to dwell in a lunar landscape – a locus of rotting trash, made up of all our discarded technological gadgets, where everything is swiftly reduced to “kipple” and “gubble” (Philip K. Dick). To put an end to this strabismus, we need to fully investigate the new4.0 e-wastes and expose their ontological and circumstantial structure, which profoundly affects our concept of space (in terms of geopolitics) and of time (as for the durability of our sensations of wellness).
A Study on the Serial Position Effect of Memory according to Illumination of LED Light
Authors: Lee Chung Won , Kim Jin Ho , Hwang In Keuk
Published: September 2019

The purpose of this study was to verify the forms of the effect of serial position effects of memory according to the illuminance of light. This study was conducted as an experimental method, and 21 adults without cognitive impairment participated in the study. The illuminance condition was designed with high illuminance condition of 1,000 lx and low illuminance condition of 300 lx. The memory task used word list of 20 items consisting of a series of pointless spellings. After memorizing the word list for 10 minutes, the participant performed a retention task 24 hours later. The memory retention task consisted of filling the empty part of the learned word and completing the word. The analysis was performed by dividing the word items into three conditions: primacy, middle, and recency. Primacy used the first item in the word list, Middle used the 10th item in the middle of the word list, and finally Recency used the last item in the word list for analysis. The result was F = 4.16 (p = .02), and showed that there was a statistically significant difference in memory retention of primacy, middle, and recency at 95% confidence level in dim condition.
Prediction of Density and Speed of Sound of Binary Ionic Liquid and Ketone Mixtures Using Artificial Neural Network
Authors: Rivera Redden Rose , Soriano Allan
Published: September 2019

The applications of ionic liquids solve a lot of major problems regarding green energy production and environment. Ionic liquids are solvents used as alternative to unfriendly traditional and hazardous solvents which reduces the negative impact to environment to a great extent. This study produced models to predict two of the basic physical properties of binary ionic liquid and ketone mixtures: density and speed of sound. The artificial neural network algorithm was used to predict these properties by varying the temperature, mole fraction, atom count in cation, methyl group count in cation, atom count in anion, hydrogen atom count in anion of ionic liquid and atom count in ketone. Total experimental data points of 2517 for density and 947 for speed of sound were used to train the algorithm and to test the network obtained. The optimum neural network structure determined for density and speed of sound of binary ionic liquid and ketone mixtures were 7-9-9-1 and 7-7-4-1 respectively; overall average percentage error of 2.45% and 2.17% respectively; and mean absolute error of 28.21 kg/m3 and 33.91 m/s respectively. The said algorithm was found applicable for the prediction of density and speed of sound of binary ionic liquid and ketone mixtures.
Properties and Characteristics of Compressed Biofuel Production from Empty Palm Fruit Bunches
Authors: Larptansuphaphol Tanuwat , Jitjumroonchokchai Penja
Published: September 2019

Thailand sits in the third place of the global rankings for crude palm oil production with an annual output of approximately 2 million tons/p.a., or 1.2% of the global output. Empty palm fruit bunches is one of residual from palm oil extraction process of Palm Oil industry. The objective of this research was to study properties and characteristics of biofuel made from empty fruit bunches and mixed with black rice hush with various composition ratios of empty palm fruit bunches and black rice husk as 100:0, 90:10, 80:20, 70:30, 60:40 and 50:50. Only the biofuels with a ratio of 100:0 and 90:10 could be formed to be compressed biofuels. The heating values of biofuels were analyzed by Gallenkamp Autobomb Calorimeter whereas other fuel properties and characteristics were tested and analyzed according to ASTM standards. The comparison results between biofuel from a mixture ratio 100:0 and 90:10 showed that the average of heating value, ash content, carbon content and combustion time (minute per one piece) were 4,672.46 and 4,199.33 cal/g, 21.73% and 29.30%, 12.07% and 16.28%, 92.33 and 63 minutes, respectively.
Physical and Chemical Properties of Philippine Coal Blended with Torrefied Biomass from Rice (Oryza sativa) Straw
Authors: Lomeda-De Mesa Rose Ann P. , Soriano Allan N. , Marquez Ariziel Ruth D. , Adornado Adonis P.
Published: September 2019

Looking at the feasibility of using rice (Oryza sativa) straw locally known as “dayami”, which the Philippines is quantitatively abundant, for power generation could help farmers reduce production cost and minimize the postharvest waste. Hence, this study’s objective is to provide a detailed knowledge of the physical and chemical properties of Philippine coal blended with torrefied rice (O. sativa) straw to efficiently use biomass for energy production. Proximate, ultimate, and calorific value analyses showed that rice (O. sativa) straw like other biomass resources are appropriate to meet the requirement of thermochemical process. When compared to pure coal, agricultural residues biomass like rice (O. sativa) straw has lower moisture and ash content, likewise nitrogen and sulfur are very low as well. Generally, blending Philippine coal with torrefied rice (O. sativa) straw would improve its quality in terms of its combustion properties thereby making these combinations of coal and biomass advantageous.
Gas-to-electricity investment planning for power system stability improvement and environmental sustainability in Nigeria
Authors: Adewuyi Oludamilare B. , Kiptoo Mark. K. , Afolayan Ayodeji F. , Adeagbo Ayooluwa P. , Senjyu Tomonobu
Published: September 2019

Power outage is a prominent feature of the current Nigerian power system. However, a properly planned energy sector can help the nations quest for energy sustainability and economic development. Techno-economic assessment of the Nigerian energy facilities for efficient gas-to-grid power integration is presented in this paper using the particle swarm optimization algorithm (PSO) for solving a voltage stability-constrained optimal power flow model on Matlab environment. Investment in gas-fired DG technology can be an economic and sustainable approach for reducing the detrimental effeccts of gas-flaring practices of the petroleum industries on the environment. The technical benefits such as voltage profile improvement and voltage stability enhancement are the main focus of the technical analysis carried out in this study.
Integrated ecosystems management of the coastal zones in the Artic zone of the Russian Federation: problems and solutions
Authors: Konovalov Alexey , Baturova Galina , Gavrilenko Tatyana , Grigorenko Olga
Published: September 2019

The article is devoted to development, implementation and information support of integrated approach to ecosystem management in the Arctic zone of the Russian Federation in the context of global climate change. According to the adopted strategic planning documents for the development of the Arctic zone of the Russian Federation, integrated ecosystems management of the coastal zones is an issue that must be dealt with expeditiously. Solution of this problem is an urgent task in the state policy of the Russian Federation. The article presents the methodology for development, implementation and information support of integrated approach to ecosystem management in the Arctic zone of the Russian Federation as well.
Some aspects regarding the influence of the anisotropy of an AA2021-T351 rolled thick plate on its tribological behaviour
Authors: Pirva Elisabeta , Tudor Andrei , Gavrus Adinel , Stoica Nicolae , Cananau Sorin
Published: September 2019

This scientific paper aims to study the influence of the anisotropy of an aluminium AA2024-T251 rolled thick plate on the surface tribological properties based on previous experimental and numerical studies concerning bulk and surface mechanical behaviour. Experimental friction tests have been made on the aluminium alloy thick plate surface using sliding of an ultra-high-molecular-weight polyethylene (UHMWPE) cylindrical pin. The used tribological test involves the generation of local motion along specified trajectories with different orientations under the action of a constant normal force and a constant slip velocity. Three different normal forces (3N, 5N, 7N) have been applied using five different sliding speeds (0.005, 0.05, 0.5, 1 and 5mm/s) along a linear trajectory of 3 mm length. In order to analyze the influence of the aluminium alloy anisotropy, the tests have been performed along three directions: a longitudinal one, corresponding to the rolling direction of the sample (0°), a transverse one, perpendicular to the rolling direction (90°), and a median direction (45°). Taking into account the observed bulk and surface anisotropy, especially concerning a fractal nature of the surface topography, an investigation was performed in order to determine its influence on the anisotropic tribological properties. In this purpose, fractal friction characteristics have been determined for the sliding process using a constant normal force Fn = 7N and the above five sliding speeds.
Immunonkologie trifft Intensivmedizin: CAR-T-Zellen
Authors: Böll Boris , Borrega Jorge Garcia , Schellongowski Peter , Subklewe Marion , von Bergwelt-Baildon Michael
Published: September 2019

CAR-T cells, genetically modified tumor-targeted t-cells, revolutionized the treatment of refractory B-cell malignancies. CAR-T cell treatment however, is invariably associated with severe immune-mediated toxicities, namely Cytokine Release Syndrome (CRS) and neurological toxicity (CRES/ICANS). Although knowledge on the pathomechanism of these toxicities is still very limited, recent findings including mouse models might allow prediction, earlier recognition and targeted treatment of patients suffering from these potentially life-threatening side effects. This article summarizes current knowledge and recent findings on the management of severe CAR-T associated toxicities and gaps of knowledge stressing the importance of an interdisciplinary approach including hematology-oncology and Intensive Care Medicine.
Intensivmedizinische Versorgung des kritisch kranken Tumorpatienten – Status Quo 2019
Authors: Beutel Gernot , Kiehl Michael , Stemmler Joachim , Shimabukuro-Vornhagen Alexander , Staudinger Thomas
Published: September 2019

In Europe, up to 25 % of the ICU patients suffer from malignant diseases. Recent studies have shown that the short term prognosis of critically ill cancer patients is determined by the severity of the acute complication leading to ICU admission, but not by the underlying malignancy. Long-term prognosis of cancer patients surviving the ICU however is given by the underlying disease and comparable to cancer patients never admitted to the ICU. In particular, survival rates of tumor patients admitted after surgery are equal to those from surgical non-tumor patients. Despite this favorable trend the ICU admission of patients suffering from malignancy is still debatable.

To define admission criteria a triage system has been developed taking into account the prognosis of the underlying disease, the overall performance status, patient will and the severity of complications. Those criteria allow us to categorize patients and to grade the intensity of treatment into “full code” treatment, a limited “ICU trial”, or palliative care without ICU intervention. In addition to those, additional factors of adverse prognosis as low performance status, number of comorbidities, admission due to cardiorespiratory arrest, organ failure due to malignancy, aspergillosis or admission after allogeneic stem cell transplantation have been identified.

This complexity requires an interdisciplinary cooperation between oncologists/haematologists and intensive care specialists and seems to be an essential clue to successfully manage critically ill cancer patients. For the future the improvement of education and training, the development of individualized therapies, and to seize the opportunity to use modern tools of data analytics and machine learning are important goals in this field.
Rechtsatriale Thromben als Komplikation bei Hämodialysekathetern und zentralen Venenkathetern
Authors: Kavalerchyk Vladyslav , Stöbe Stephan , Hagendorff Andreas , Augustyniak Jaroslaw , Staudt Alexander
Published: September 2019

Anamnese Fall 1: Vorstellung einer 65-jährigen Patientin mit Nachweis multipler zerebraler Infarktläsionen, nach mikrochirurgischer Resektion einer benignen Raumforderung, zur TTE/TEE zur Detektion kardialer Embolie-Quellen. Perioperativ erfolgte die Anlage eines zentralen Venenkatheters. Fall 2: Vorstellung einer 59-jährigen Patientin zur TTE/TEE bei Verdacht auf Endokarditis im Rahmen einer Urosepsis infolge einer infizierten Harnstauungsniere links bei disloziertem Doppel-J-Katheter. 4 Monate zuvor wurde ein Vorhofkatheter angelegt.

Diagnostik/Befunde In beiden Fällen konnten mithilfe der Echokardiografie thrombotische Formation im Bereich des rechten Vorhofs detektiert werden. In Fall 2 konnten zudem morphologische und funktionelle Veränderungen des rechten Vorhofs und Ventrikels sowie der Trikuspidalklappe nachgewiesen werden.

Therapie und Verlauf Während bei der Patientin in Fall 1 eine medikamentöse therapeutische Antikoagulation mit Phenprocoumon durchgeführt wurde, wurde bei der Patientin in Fall 2, v. a. aufgrund des erhöhten thromboembolischen Risikos und der funktionellen Beeinträchtigung der Trikuspidalklappe, die Indikation zur chirurgischen Thrombektomie gestellt.

Folgerung Mithilfe der Echokardiografie können thrombotische Formationen des rechten Herzens detektiert werden. Das weitere Therapieregime sollte jeweils individuell und interdisziplinär festgelegt werden.
Comparison of International Therapy Guidelines with Regard to the Treatment of Malignant Catatonia
Authors: Schönfeldt-Lecuona Carlos , Cronemeyer Maximilian , Hiesener Lilli , Connemann Bernhard J. , Gahr Maximilian , Sartorius Alexander , Mühlbauer Viktoria
Published: September 2019

Objective Malignant catatonia (MC) is an extremely rare, life-threatening disorder. It is characterized by catatonic symptoms accompanied by autonomic instability, hyperthermia, and changes in laboratory values. In many cases, MC is not recognized as such. Evidence-based guidelines are essential to ensure quality of treatment, but what do current national and international guidelines recommend?

Method Online search for international guidelines from English-, French-, Italian-, and German-speaking countries whose medical care meets high standards addressing the treatment of MC. These were analyzed and compared regarding statements on MC, recommendations, and strength of scientific evidence.

Results Fifteen of the identified guidelines were included. Only 5 of 15 comment on the treatment of MC. As for other rare diseases, no detailed recommendations are available. Suggested therapies are limited to benzodiazepines and electroconvulsive therapy. Levels of evidence and grades of recommendation are predominantly low.

Conclusion Many international guidelines do not mention MC. It is not possible to derive a clear algorithm for the treatment of MC from most current guidelines. A thorough update of most guidelines appears to be necessary. Lack of awareness and knowledge of MC among physicians and medical professionals might lead to inadequate or delayed care, worsened outcome, or death.
Work–Life Integration and Time Management Strategies
Authors: Gade Lindsey , Yeo Heather L.
Published: September 2019

When choosing a career as a surgeon, we knowingly dedicate ourselves to a lifetime of service and education. Our commitment as physicians is but one of many commitments in the larger scheme of life where we function as family members, friends, athletes, and numerous other roles. Work and life are often described as two separate entities diametrically opposed to each other. In reality, personal and professional goals are part of a continuum where work is a major part of our lives and who we are as people and is not necessarily separate from the others. The goal-directed nature with which we approach our responsibilities as surgeons should be applied to all domains of life. As we progress along the training paradigm from intern to attending, control over time allocation increases. Understanding oneself, determining priorities, applying realistic expectations, cultivating a supportive environment, setting personal and professional goals, and being held accountable for progress and completion of these goals will allow us to utilize limited time efficiently to achieve what we individually desire from life.
Alergia alimentar ao trigo
Authors: Pinto Aline Pereira Reis , de Mello Elza Daniel
Published: September 2019

A alergia alimentar é o nome dado para as reações adversas aos alimentos que circundam mecanismos imunológicos, ocasionando então uma gama de manifestações clínicas. Aproximadamente 6% das crianças com idade inferior a 3 anos, e cerca de 4% dos adultos apresentam desordens alérgicas causadas por alimentos. A alergia alimentar ao trigo (AAT) ocorre quando o sistema imunológico do organismo se torna sensível e reage a qualquer uma das proteínas do trigo. A reação alérgica é classificada conforme o mecanismo imunológico implicado, podendo ser mediada por IgE ou por reações mistas, quando ocorre o envolvimento de citocinas e linfócitos T pró-inflamatórios, ou imunocomplexos, ou ainda reações citotóxicas. O presente estudo tem por objetivo fazer uma revisão sobre a alergia alimentar ao trigo (AAT), englobando sua manifestação clínica, diagnósticos, e tratamento. A pesquisa de estudos foi feita nas bases de dados de referência Lilacs e Scielo, utilizando os seguintes descritores em saúde: alergia, reação alérgica e trigo. Em relação ao tratamento, o mais eficiente e garantido ainda é a extração absoluta do alérgeno da dieta, no caso do trigo. Diante das considerações, o referido estudo verificou a preocupação frequente quanto ao aumento das alergias alimentares em nível mundial, e salienta-se a importância de novos estudos relacionados ao tratamento dos alérgicos ao trigo no intuito de reduzir as reações alérgicas, manter o estado nutricional, e aumentar a qualidade de vida.