bluuebunny/crossref_metadata_2025 huggingface dataset:
Emergence of mucormycosis in post-COVID infections in tertiary care hospital Warangal
Authors: Padmaja Goteti V. , Kumar Shanigarapu R.
Published: July 2024

Introduction:

Mucormycosis is an emerging fungal infection associated with high mortality, especially in post-COVID state. Mucormycosis, though fungal spores ubiquitous in the environment, is a clinical disease that occurs in immunocompromised conditions. However, the incidence of mucormycosis is enormously increased in post-COVID-19 infections and in those who are immunocompromised. It presents as rhino-orbital-cerebral mucormycosis. The diagnosis is done by KOH mount and culture on Sabouraud dextrose agar (SDA). The identification of post-COVID risk factors, clinical features, and KOH mount helps in early diagnosis. Early treatment helps in preventing progressive tissue invasion, surgical debridement and thus improves the outcome.

Aims and Objectives:

To establish etiological agents of mucormycosis.

To establish the relation of diabetes mellitus, steroid usage, oxygen inhalation, and other risk factors in postCOVID patients suspected with mucormycosis.

To study and establish associated high-risk factors for the sudden explosion of mucormycosis cases in post-COVID state.

Material and Methods:

The study was done on a total of 81 patients of suspected mucormycosis admitted at MGM Hospital and 20 controls of post-COVID patients over a period of 3 months. Demographic features, predisposing conditions, clinical features, culture characters, and radiological features were all obtained and analyzed.

Results:

The history of diabetes mellitus, steroid usage, and oxygen inhalation were analyzed. Among 81 debrided tissue samples received, 52 were KOH mount positive and out of them only 32 showed growths on SDA. Among them, 9 wereRhizopus, 13 wereMucor, and 10 were other species.

Conclusion:

Mucormycosis is a rare and uncommon disease in the past; However, in the COVID-19 pandemic, its association with post-COVID state is established. The common presentation of rhino-orbital-cerebral mucormycosis is dreadful; however, early diagnosis and prompt treatment in time will decrease mortality and morbidity remarkably.
Rehabilitation of an orbital defect using a silicone prosthesis with a custom ocular portion – A case report
Authors: Ramesh Janaki , Basapogu Sreeramulu , Pyla Vineela , Velamakuri Bharat C.
Published: July 2024

The surgical removal of the orbit can be a psychologically traumatic event that may incapacitate patients. The prosthetic rehabilitation of such defects is complex and artistically driven. This case report describes the aesthetic rehabilitation of a patient who had undergone unilateral orbital exenteration due to COVID-19-associated rhino-orbital mucormycosis. This technique uses commonly available materials in the dental clinic and artists’ colors for the fabrication of a custom ocular portion of the silicone orbital prosthesis that closely matches the natural eye color of the patient.
Efficacy and safety of combination therapy (desmopressin with tolterodine) in nocturnal enuresis in children: An institutional experience
Authors: Bansal Rajan , Rahul Nekkanti , Qazi Ifrah A. , Pogula Veda Murthy Reddy , Reddy Sandeep K.
Published: July 2024

Background:

Nocturnal enuresis is one of the most common problems of childhood. Desmopressin is started as a first-line treatment along with essential behavioral therapy like fluid restriction before bed and sleep hygiene. Given the high relapse rates seen with using desmopressin alone, the need of the hour is to reinforce its effects using another agent so that the remission is long-lasting.

Aim:

The aim is to look for efficacy and safety of treatment using combination therapy of desmopressin with tolterodine in nocturnal enuresis and further to look for the relapse rate with a structured withdrawal regimen.

Results:

A total of 150 patients of nocturnal enuresis were included in the study. Ninety patients (75%) were males, and 30 patients (25%) were females. The median age of patients was 12 years. Evaluation of the consequences at 1 month, 3 months, and 6 months revealed complete remission in 87 patients (72.5%), 105 patients (87.5%), and 105 patients (87.5%), respectively. After 12 months with desmopressin + tolterodine, it was found that 99 patients (82.5%) had complete remission, six patients (5%) had a relapse, and 12.5% of individuals still suffered from enuresis. The relapse rate on follow-up of 6 months after complete cessation of the treatment of 120 patients was 5% in combination therapy. The complication rate with combination therapy is 4.17%. There is no significant effect of gender or age on improvement with combination therapy.

Conclusion:

Desmopressin given in combination with tolterodine is safe and effective as combination therapy for treating nocturnal enuresis, and in most cases, long-term remissions can be achieved.
Is the current postgraduation batch less fortunate by missing the crucial junior resident 2 phase? A thought
Authors: Mukhida Sahjid , Kannuri Sriram , Das Nikunja K. , Patil Rajashri , Bhaumik Shalini
Published: July 2024

During Covid-19 core areas of medical education have taken a beating. After the first wave of COVID 19, PG admissions took place between May and July 2020. Due to the second wave of COVID 19, NEET PG 2021 exam was conducted 9 months late. JR 2 phase is also the time when the PGs have interdepartmental and outside postings in other speciality and super speciality sections, but due to the unavailability of a new batch, this thing also got hampered as the departments were reluctant to send them. Most of the PG students were not able to start work on mandatory requirements for exam due to massive workload with availability of lesser workforce. The overall conclusion is that the current PG batch students are losers in their JR 2 phase of learning, training, and teaching and the reason behind that is constant delays due to litigations.
Квантовая схема для атаки на протокол квантовой криптографии с фазово-временным кодированием
Authors: Kronberg Dmitry Anatolevich
Published: July 2024

Основным свойством квантовой криптографии является возможность строгого доказательства стойкости против любых действий противника. Однако доказательство стойкости является сложным и может содержать ошибки. Неполнота доказательства стойкости создает риск уязвимости, т. е. ситуации, при которой противник обладает полным или частичным знанием о криптографическом ключе. В этой работе предлагается квантовая схема атаки на двупараметрический протокол квантовой криптографии с фазово-временным кодированием, которая демонстрирует его уязвимость. Показано, что построенная атака является относительно простой и требует лишь трех дополнительных кубитов. Обсуждаются ошибки в доказательстве стойкости, которые сделали возможной построенную атаку.
Can LLMs help with XML?
Authors: DeRose Steven J.
Published: July 2024

LLMs have become popular for a huge range of tasks. They train over vast collections of text, yet largely discard markup of all kinds. Historically, many AI and NLP tools just stripped out not only explicit markup but even punctuation, case distinctions, or inflection. Recent work is a bit less drastic, but still commonly discards even simple notions like paragraphing, headings, block quotes, and notes. Likewise, few systems create output with any useful markup beyond paragraph breaks (if that). The conventions of written language leverage all these things, and it seems odd that LLMs should waste the opportunity of using them.

“Cleaning” to avoid inappropriate text is also ubiquitous and also leads to unintended consequences. Exclusion granularity is coarse – a work may be discarded because it (perhaps critically) includes a rude quote. Just like markup “cleaning,” text selection may get minimal and non-expert attention. Censorship is often done by word-list, or worse, string-list, and even the best-known lists seem almost random.

Underlying all these issues is the substitution of deceptively simple proxies for more complex and subtle goals. This is understandable especially at scale; but it has extensive and varied consequences. Such cleaning may seem to work fine, but we have little idea of precisely where, how often, and in how biased a way, it goes wrong. Figuring that out post facto is hard, in part because there is little transparency about any of these decisions and processes.

How can markup (broadly construed) and LLMs work better together? Why and how can LLMs make use of structure, both going in and coming out? Can LLMs help with structure-related questions and tasks? How can users construct effective prompts in this area? And finally, how does the semantic orientation of markup relate to LLM's probabilistic rather than semantic treatment of language? This paper begins to explore such questions.
Stretching XPath: Three Testing Tales
Authors: Galtman Amanda
Published: July 2024

This paper describes three testing situations that can be addressed by markup-technology functionality whose primary uses are fairly different from those testing situations. One testing situation involves ensuring that certain kinds of test verifications don’t pass for the wrong reason. Another situation involves testing an XSLT template both cleanly and compactly. The third situation involves reducing maintenance of schema-valid and schema-invalid XML fragments when testing a schema. Software testing frameworks are sometimes sparse in their own functionality, but the XSpec and BaseX software discussed here can use rich functionality from the XML technologies on which they rest.
“Why are some technologies more successful than others? And why are my predictions usually wrong?”
Authors: Kay Michael
Published: July 2024

If asked “what made XML successful”, I could come up with many answers, ranging from ease of implementation through availability of support tools to dumb luck and good timing. But if, back in the day, I had been asked “will the World Wide Web take off”, I would have given the wrong answer: I could see the positive things it shared with current succesful technologies, like SGML, but I couldn’t have predicted the rise of TCP/IP that made the Web feasible. It’s not too hard to recognize the importance of low cost or potential benefits of promising technologies but much more difficult to predict the effects of timing or the endorsement of trusted influencers. And it is most difficult for us to see our own strong inbuilt biases that make prediction risky.
Variations on an Invisible Theme
Authors: Lumley John
Published: July 2024

InvisibleXML (iXML) is designed as a lightweight context-free grammar notation to describe a mapping between structured textual data and an XML representation of that structure. As such it is being used practically and several implementations of processors exist, for various execution environments. But one of the perhaps underexploited features of iXML is that an iXML grammar text can itself be parsed by the iXML grammar definition to produce an equivalent XML representation of that grammar (i.e. as a series of production rules). With the power of XSLT to analyse, modify and generate such an XML representation, there are a number of interesting possibilities for expanding the scope of Invisible XML by so doing. This paper describes some of the types of manipulation that can be achieved, giving examples ranging from multi-language support to tree-depth reduction, automated generation of a parser for XPath/XQuery and “round-tripping” via generated XSLT transforms, and outlines some of the practical problems encountered.
White-box filtering attacks breaking SEL masking: from exponential to polynomial time
Authors: Charlès Alex , Udovenko Aleksei
Published: July 2024

This work proposes a new white-box attack technique called filtering, which can be combined with any other trace-based attack method. The idea is to filter the traces based on the value of an intermediate variable in the implementation, aiming to fix a share of a sensitive value and degrade the security of an involved masking scheme.Coupled with LDA (filtered LDA, FLDA), it leads to an attack defeating the state-ofthe-art SEL masking scheme (CHES 2021) of arbitrary degree and number of linear shares with quartic complexity in the window size. In comparison, the current best attacks have exponential complexities in the degree (higher degree decoding analysis, HDDA), in the number of linear shares (higher-order differential computation analysis, HODCA), or the window size (white-box learning parity with noise, WBLPN). The attack exploits the key idea of the SEL scheme - an efficient parallel combination of the nonlinear and linear masking schemes. We conclude that a proper composition of masking schemes is essential for security.In addition, we propose several optimizations for linear algebraic attacks: redundant node removal (RNR), optimized parity check matrix usage, and chosen-plaintext filtering (CPF), significantly improving the performance of security evaluation of white-box implementations.
A Deep Analysis of two Glitch-Free Hardware Masking Schemes SESYM and LMDPL
Authors: Müller Nicolai , Lammers Daniel , Moradi Amir
Published: July 2024

In the context of masking, which is the dominant technique for protecting cryptographic hardware designs against Side-Channel Analysis (SCA) attacks, the focus has long been on the design of masking schemes that guarantee provable security in the presence of glitches. Unfortunately, achieving this comes at the cost of increased latency, since registers are required to stop glitch propagation. Previous work has attempted to reduce latency by eliminating registers, but the exponential increase in area makes such approaches impractical. Some relatively new attempts have used Dual-Rail Pre-charge (DRP) logic styles to avoid glitches in algorithmically masked circuits. Promising approaches in this area include LUT-based Masked Dual-Rail with Pre-charge Logic (LMDPL) and Self-Synchronized Masking (SESYM), presented at CHES 2020 and CHES 2022 respectively. Both schemes allow masking of arbitrary functions with only one cycle latency. However, even if glitches no longer occur, there are other physical defaults that may violate the security of a glitch-free masked circuit. The imbalanced delay of dual rails is a known security problem for DRP logic styles such as Wave Dynamic Differential Logic (WDDL), but is not covered by the known security models, e.g., robust probing model.In this work, we illustrate that imbalanced signal delays pose a threat to the security of algorithmically masked circuits implemented with DRP logic, both in theory and practice. Notably, we underscore the security of LMDPL even when delays are taken into account, contrasting with the vulnerability observed in SESYM under similar conditions. Consequently, our findings highlight the critical importance of addressing imbalanced delays in the design of masked circuits using DRP logic. In particular, our findings motivate the need for an appropriate security model, and imply that relying solely on the probing security model and avoiding glitches may be insufficient to construct secure circuits.
THE PERFORMANCE ANALYSIS OF MIDWIFERY SERVICES IN SAMARINDA CITY
Authors: Johan Herni
Published: July 2024

Antenatal care (ANC) was an essential part of healthcare services for pregnant women. Various studies showed that antenatal care could improve care experiences and health outcomes for pregnant women and newborns. This study aimed to analyze the factors influencing the performance of midwives in antenatal care services in Samarinda City. This research used a quantitative method with a cross-sectional approach. The respondents of the study were the entire population, totaling 23 people, and were obtained through a questionnaire. Data processing was done with SPSS and data analysis used statistical tests, including univariate, bivariate, and multivariate analyses. The results of the study showed that there was a relationship between age, employee status, and years of service with the performance of midwives in ANC services. This study recommended that the Health Department and midwives establish human resource management policies for midwives with non-permanent employee status and regulate incentives that could improve performance in ANC services. Additionally, it was important to carry out antenatal care with full responsibility and seriousness, considering that these services were related to the Maternal and Child Health program that needed to be achieved.
Bromelain Administration Ameliorates Neurobehavioural Deficits Mediated by Cadmium Neurotoxicity via Oxido-Nitrosative Stress, Cholinergic and Neuroinflammatory Modulations in Male Wistar Rats
Authors: Bayo-Olugbami Adedamola ,   Neuroscience Unit, Department of Physiology, Osun State University, Osogbo, Nigeria, Muritala Al-Hassan , Abdur-Rahman Habeebullahi , Bakare Ah-med , Arogundade Tolulope , Atere Tope , Owoyele Bamidele ,   Department of Physiology, Adeleke University, Ede, Nigeria,   Department of Anatomy, Adeleke University, Ede, Nigeria,   Department of Physiology, Adeleke University, Ede, Nigeria,   Division of Neurobiology, Department of Human Anatomy, Redeemer’s University, Ede, Nigeria,   Department of Medical Biochemistry, Osun State University, Osogbo, Nigeria,   Neuroscience & Inflammation Unit, Department of Physiology, University of Ilorin, Ilorin, Nigeria
Published: July 2024

Cadmium (Cd) is a toxic metal widely present in the environment. Certain plant-based natural or active compounds are gaining attention for their neuroprotective effects against chemically induced toxicity. However, there is no report on the impact of bromelain on Cd-induced neurotoxicity, hence the rationale behind this study. Twenty-four adult male rats were divided into four groups: control (normal saline, 5mL/kg), Cd (orally, 5mg/kg), bromelain (50mg/kg), and Cd+bromelain. Rats received bromelain or normal saline for 14 days. Cd was administered concurrently with bromelain and normal saline in the last 7 days. Neurobehavioural responses to locomotion, cognition, anxiety, and depression were assessed. Plasma was assayed for the levels of superoxide dismutase (SOD) and malondialdehyde (MDA), while the prefrontal cortex (PFC) was processed for the concentration of Cd and levels of SOD, MDA, nitric oxide (NO), acetylcholinesterase (AChE), interleukin-6 (IL-6), and tumour necrotic factor-α (TNF-α). Data were analysed using one-way ANOVA (Tukey’s post hoc), with the level of significance set at p<0.05. Exposure to Cd caused a significant behavioural deficit, as indicated by a decline in motor coordination, memory index, and enhanced depressive and anxiety-like behaviours. Biochemically, Cd concentration was significantly increased in the PFC of Cd group compared to the control. There was a reduction in the level of SOD and increased levels of MDA, NO, IL-6, AChE, and TNF-α following Cd exposure. Bromelain significantly improved the behavioural outcomes and reversed some of the biochemical markers altered by Cd toxicity. Bromelain reduced neurobehavioural impairment, cholinergic alteration, and oxido-inflammatory deficits induced by Cd exposure.
Fase Perkembangan Anak Sekolah Dasar dan Pembinaannya dalam Perspektif Islam
Authors: Ekawati Meilinda , Setti Azkiy Silva , Mulyati Siti Triani Amelia
Published: July 2024

Penelitian ini membandingkan pengertian psikologis dengan konsepsi Islam tentang anak, tahapan perkembangannya, dan pola asuh orang tua dalam perspektif Islam berdasarkan Al-Qur'an dan Al Hadits. Tujuannya adalah untuk memberikan kontribusi ilmiah terhadap pemahaman kita tentang bagaimana mendidik anak sesuai dengan keyakinan Islam. Penelitian ini mengkaji teks-teks Al-Quran dan Al Hadits serta sumber informasi penting psikologis lainnya dengan menggunakan metode hermeneutika psikologis. Setelah itu dilakukan perbandingan dan analisis isi terhadap data tersebut. Temuan penelitian menunjukkan bahwa konsepsi Islam dan psikologis anak berbeda satu sama lain. Dalam bidang psikologi, anak diartikan sebagai seseorang yang berusia kurang dari 14 tahun yang kebutuhan fisik dan psikisnya masih terpenuhi oleh lingkungannya. Sebaliknya anak dalam Islam adalah seseorang yang lahir dari perkawinan yang sah antara suami dan istri, karena keyakinan Islam memandang perkawinan sebagai satu-satunya kewajiban terhadap keturunan.
ABORDAGENS MODERNAS EM CIRURGIA DE URGÊNCIA E EMERGÊNCIA
Authors: Oliveira Junior José Ferraz de , Araujo Rocio Cristal Enciso , Lens Luigi Neves , Couto Gabriela Silva do , Borchart Eduardo Felipe Camargo
Published: July 2024

Este artigo aborda abordagens modernas em cirurgia de urgência e emergência, com destaque para a importância da preparação pré-operatória, técnicas cirúrgicas inovadoras, manejo de complicações pós-operatórias e uso de recursos tecnológicos. Aspectos éticos e legais, treinamento e educação continuada, abordagens multidisciplinares, telemedicina e telessaúde, gestão de recursos e protocolos institucionais, pesquisa e inovação também são discutidos. Os resultados e conclusões alcançados são apresentados. Destaca-se a preparação pré-operatória, o papel das técnicas cirúrgicas inovadoras e o manejo de complicações pós-operatórias. Avanços tecnológicos recentes, como robótica, inteligência artificial e realidade virtual, também são explorados. Questões éticas e legais, treinamento e educação continuada, abordagem multidisciplinar, telemedicina e telessaúde, gestão de recursos e protocolos institucionais, pesquisa e inovação são discutidos. O artigo contribui para a melhoria da prática da cirurgia de urgência e emergência e promove uma abordagem segura, eficiente e baseada em evidências.
Evaluation of anti-radiation efficacy of the Staphylococcus aureus-derived therapeutic agent
Authors: Gaynutdinov TR , Ryzhkin SA , Shavaliev RF , Vagin KN , Kurbangaleev YaM , Kalimullin FH , Plotnikova EM , Idrisov AM , Ohrimenko SE , Mayorova EN
Published: July 2024

The study is relevant due to the fact that the decrease in microbial toxicity observed during the radio-inactivation of microorganisms is accompanied by synthesis of radioprotective substances and exertion of the radioprotective effects associated with administration of such microbial agents to exposed animals. The study was aimed to assess radioprotective efficacy of the exposed Staphylococcus aureus variants. The study showed that the Staphylococcus aureus culture treated with a single dose of gamma radiation (30–40 kGy) ensured protection of 55–66% of the lethally irradiated animals. Multiple exposures of the test microorganism to the gradually increasing doses of gamma radiation induced an even larger increase in radioresistance resulting from the synthesis of endogenic radioprotectors, particularly peroxidase, the antioxidant enzyme, and IL1β cytokine, ensuring interception of the radiation-induced toxic radicals and thereby preventing postexposure pancytopenia in the bone marrow. The experiments involving white mice exposed to the absolutely lethal gamma radiation doses (7.9 Gy, LD100/30) showed that a single subcutaneous administration of the St. aureus radioresistant variant (strain 209R70) in a dose of 2 × 108 bacterial cells per animal 3 days after the exposure ensured the 77.7% survival rate, while 100% of untreated animals died. Based on the findings it was concluded that inclusion of the exposed agents of microbial origin would make it possible to increase the efficacy of the combination radioprotectors.
Morphological characteristics of toxic brain damage
Authors: Gaykova ON , Kozlov AA , Katretskaya GG , Melnikova MV , Melekhova AS , Bondarenko AA , Sokolova YuO , Bazhanova ED
Published: July 2024

The effects of various toxicants on the body tissues cause tissue abnormalities resulting in dystrophic changes and necrosis. The nervous system is the most vulnerable to the effects of exogenic substances, both chemical and biological, due to high metabolic activity and the cells' incapability of self-renewal. Neurotoxicants lead to disturbances of cellular nutrition and eventually to neurodegeneration. Neurons can die due to both apoptosis and necrosis.
Comparative assessment of toxic pulmonary edema caused by poisoning with carbonyl chloride and fluoroplastic thermal degradation products
Authors: Yaroshenko DM , Lopatko VS , Tolkach PG , Vengerovich NG , Basharin VA
Published: July 2024

Poisoning with acylating pulmonary toxicants results in toxic pulmonary edema (TPE), the approaches to treatment of which are limited. The lung injury similar to poisoning with acylating pulmonary toxicants can be simulation through body’s exposure to the fluoroplastic thermal degradation products containing perfluoroisobutylene. The study was aimed to compare toxic pulmonary edema manifestations in the laboratory animals poisoned with an acylating pulmonary toxicant (carbonyl chloride) and fluoroplastic thermal degradation products. Animals (male rats, n = 78) were divided into three groups: controls; Poisoning 1, where the animals were exposed to carbonyl chloride; Poisoning 2, where the animals were exposed to the fluoroplastic thermal degradation products. The animals’ lung/body ratio was determined and the partial pressure of arterial oxygen (PaO2) and carbon dioxide (PaCO2) was assesed 10 min, 1, 3, 6, 24, and 48 h after the exposure. Histological examination of lung tissue was performed 3 and 6 h after the exposure. The increase in the lung/body ratio, decrease in PaO2, and increase in PaCO2 relative to controls were revealed 3, 6, 24, and 48 h after the exposure to carbonyl chloride and fluoroplastic thermal degradation products. The signs of the interstitial toxic pulmonary edema phase were detected 3 h after the exposure to the studied toxicants, and the signs of alveolar phase were revealed after 6 h. Similar changes were identified in animals of the experimental groups. The findings have shown that the exposure to carbonyl chloride and the fluoroplastic thermal degradation products containing perfluoroisobutylene lead to similar changes in the early post-intoxication period.
The Concept of Recidivism for Juvenile Criminal Offenders in Law Number 1 of 2023 on the Indonesian Criminal Code
Authors: Fawwaz Muhammad Fairuz Khansa ,   Master of Law Study Program, Faculty of Law, Diponegoro University, Indonesia, 50241., Soponyono Eko ,   Master of Law Study Program, Faculty of Law, Diponegoro University, Indonesia, 50241.
Published: July 2024

The Juvenile Criminal Justice System (JCJS) in Indonesia is inextricably linked to the country's Criminal Law Policy. Law Number 11 of 2012 concerning the Juvenile Criminal Justice System represents a significant reform effort in Indonesia by introducing the concept of diversion to address juvenile delinquency. Diversion allows for the resolution of juvenile cases outside the formal criminal justice process, under certain conditions, to avoid stigmatization and promote restorative justice. This study employs a normative juridical approach through legal comparison. The research specification is descriptive, utilizing secondary data sources and types. Data collection is based on literature/documents, and the data analysis technique used is qualitative analysis. The JCJS Law in Indonesia needs clearer and more comprehensive regulations regarding recidivism. Furthermore, the JCJS Law tends to focus more on the recovery and reintegration of juveniles, with insufficient emphasis on preventing recidivism. There is a conceptual change in recidivism within the Indonesian Criminal Code. The Dutch Criminal Code (Wetboek van Strafrecht), which has traditionally applied a special recidivism concept with an intermediate system, will be changed to an "Algemene Recidive" system. Article 112 of the Indonesian Criminal Code stipulates the obligation to seek diversion for juveniles.
ENTRE O NARRADOR DA IMAGEM E OS DA HISTÓRIA
Authors: Ferreira Jamylle de Almeida
Published: July 2024

Ao comemorarmos o bicentenário da independência, propomos uma reflexão que toca a questão do processo de constituição da identidade nacional. O objeto é a polêmica representação da confecção da bandeira do Brasil Republicano como signo imagético na obra A Pátria, de 1919. Apesar de o autor do quadro não se comprometer com uma representação personalista e quantitativa, a cena ficou conhecida como a confecção do primeiro exemplar da bandeira republicana pela esposa e filhas de Benjamin Constant. Entretanto, diferente do que aponta a memória social construída e manipulada, a primeira bandeira do Brasil Republicano foi bordada por Flora Simas de Carvalho, que teria passado pela vida no anonimato, não fosse esse feito. A obra de arte se permite interpretar dentro de certos limites estabelecidos pelo autor. Para além dos que nela são evidenciados, o querepresentam os que são esquecidos?
FLANCO LESTE DO ENTORNO ESTRATÉGICO DO BRASIL
Authors: Visentini Paulo Fagundes
Published: July 2024

Na época da independência do Brasil, em 1822, o Atlântico Sul e o litoral africano eram vitais para a segurança nacional, mas depois perderam relevância. Todavia, há algum tempo a análise do Entorno Estratégico do Brasil passou a considerar a configuração de um flanco oriental, constituído pelo Oceano Atlântico Sul, bem como pelo litoral ocidental africano. A extroversão da economia brasileira, a identificação de recursos naturais off-shore (especialmente petróleo) e a crescente presença de atores extrarregionais, como a China, na área estudada, deram substância ao tema em sua dimensão securitária. Embora o Atlântico Sul não seja o espaço marítimo mais relevante estrategicamente, sua importância cresce rapidamente. Assim, o capítulo busca analisar a presença chinesa, norte-americana e britânica, que já caracteriza uma disputa acirrada, em um cenário de preocupação para o Brasil e os países da região, associados na Zona de Paz e Cooperação do Atlântico Sul (ZOPACAS).
Metastatic colorectal cancer cells upregulate SMLR1 that interacts with tumor-associated macrophages in the liver
Authors: Wong Chi Wut , Wang Lihua , Balcazar Jorge Prado , Chen Yong , Shen Xiling
Published: July 2024

Colorectal cancer liver metastasis (CRLM) is the most common form of metastatic colorectal cancer (CRC), one of the leading causes of cancer deaths. The CRLM microenvironment tends to be more immunosuppressive, making immunotherapy less effective. By transcriptomics analysis, we discovered that small leucine-rich protein 1 (SMLR1) is upregulated in CRC liver metastases compared to primary tumors. High SMLR1 expression by the cancer is associated with poor prognosis. Proteomics analysis and cell retention assay revealed associations between SMLR1 and mannose receptor C-type 1 (MRC1, CD206) and sialic acid binding Ig-like lectin 1 (SIGLEC1, CD169) expressed on tumor-associated macrophages in the metastatic liver microenvironment. These data provide evidence that cancer cells modulate their metastatic niche via the upregulation of SMLR1 and physical interaction with immunosuppressive macrophages in the liver.
Analisis Perlindungan Hukum Terhadap Pekerja Harian Lepas Menurut Undang-Undang No. 13 Tahun 2003 Tentang Ketenagakerjaan
Authors: Raflianto Muhammad Caesar , Sayudi Akbar
Published: July 2024

Legal protection for casual daily workers is contained in Law Number 13 of 2003. Protection for workers includes social, economic and technical protection. However, casual daily workers do not yet receive full protection from a social, economic and technical perspective. Many workers' rights have not been fulfilled, such as wages, and there is no social security for workers, if workers experience work accidents or occupational health problems while carrying out their work.This research aims to determine the regulation of casual daily workers and legal protection for casual daily workers according to Law Number 13 of 2003 concerning Employment. This research is a type of normative legal research. The data used is secondary data consisting of primary, secondary and tertiary legal materials followed by document studies, regulations and related theories which produce descriptive-analytical data. The research results show that the regulation of casual daily workers is based on PKWTT which can be made in written or verbal form. Meanwhile, the PKWT provisions in Article 51 paragraph (2) of Law Number 13 of 2003 are required to be in writing, this aims to provide protection and certainty to workers/laborers. Legal protection for casual daily workers includes: protection of wages, protection of workers' health and safety, and protection of Social Security. It is hoped that relevant employers and governments will pay more attention to the rights of each worker so that they are adjusted to the mandate of Law Number 13 of 2003, because casual daily workers also work based on work agreements and have the same rights.
Hak Warga Negara dalam Menyampaikan Kebebasan Berpendapat Berdasarkan Peraturan Perundang-Undangan Perspektif Fiqh Siyasah
Authors: Dachi Adliano Dino , Khalid Khalid
Published: July 2024

Freedom of speech is one of the most important human rights. Freedom of opinion requires individuals to express opinions and opinions without fear of retaliation or punishment from the government or other entities. The important role of freedom of opinion is closely related to human rights in ensuring an open and democratic political system and can help in fighting for other human rights. In this research, it will examine more deeply about freedom of opinion based on laws and regulations that aim to achieve the right of freedom in expressing opinions on something reviewed from Law Number 9 of 1998 concerning Freedom to Express Opinions in Public with the perspective of Fiqh Siyasah and Maqashid Syari'ah.
Keywords: Opinion, Human Rights, Fiqh Siyasah
The Position of The Honorary Council of The Constitutional Court in the Indonesian Legal Order
Authors: Juanda Juanda , Rizkia Nanda Dwi
Published: July 2024

ABSTRACT
This research is qualitative research with a normative approach. The data that researchers use in this article is secondary data that researchers obtained from various credible sources such as legal regulations, books, articles, scientific and various other sources. The data that the researchers used were analyzed using three legal analysis techniques, namely normative legal analysis techniques, historical legal analysis techniques, and telelogical legal analysis techniques. The result in this article show The Honorary Council of the Constitutional Court has existed since the enactment of Law no. 24 of 2003, namely Article 23 paragraph (3), which states that; "Requests for dishonorable dismissal as intended in paragraph (2) letters b, c, d, f and g are made after the person concerned has been given the opportunity to defend himself before the Honorary Council of the Constitutional Court." Then in 2006 the Constitutional Court established a Regulation concerning the Honorary Council of the Constitutional Court, namely regulation Number 10/PMK/2006. Regarding changes to Law no. 24 of 2003, the Honorary Council was only defined after the enactment of Law no. 8 of 2011. Article 1 number 4 of Law no. 8 of 2011 states that: "The Honorary Council of the Constitutional Court is a device established by the Constitutional Court to monitor, examine and recommend actions against Constitutional Judges, who are suspected of violating the Code of Ethics and Code of Conduct for Constitutional Judges. Thus, the statement regarding the Honorary Assembly of the Constitutional Court only existing in 2023 is not justified.Theologically, the formation of the constitutional court has objectives, duties and authority, among others: 1. The Honorary Council has the authority to maintain the dignity and honor of the Court. 2. The Honorary Council has the authority to examine and decide on alleged violations of the Code of Ethics and Conduct of Constitutional Judges 3. Alleged violations of the Code of Ethics and Conduct of Constitutional Judges can be examined and decided within a maximum of 30 working days from the time the report is recorded in e-BRLTP 4. In terms of a period of 30 days If the inspection has not been completed, it can be extended for a maximum of 15 working days.
Perlindungan Hukum Para Pihak Apabila Terjadi Wanprestasi Lelang Non Eksekusi Sukarela Secara Online Tanpa Pejabat Lelang
Authors: Anita Dewi , Nurdiani Herlin , Dania Tasya , Maskanah Umi
Published: July 2024

As explained, auctions basically adopt the characteristics of a sale and purchase agreement (1457 BW), where the elements of price and goods are important elements. The difference is that auctions require the presence of an Auction Officer, especially for execution auctions and mandatory non-execution auctions. Auctions have special regulations (Lex Specialis), namely Vendu Reglement and Vendu Instructie as auction regulations which are still valid today. Apart from that, the implementation of auctions is also regulated in PMK 213/PMK.06/2020 concerning Instructions for Implementing Auctions. Online auctions are carried out through the e-Marketplace Auction Platform where the implementation is usually carried out without an auction official, for example auctions on eBay. The purpose of this research is to determine protection for parties who experience losses due to default. This research is legal research with a statutory approach, conceptual approach and case approach. The research results obtained are that the validity of online voluntary non-execution auctions without the presence of an auction official is valid by adopting the characteristics of a sale and purchase agreement. And the protection for the parties is the legal protection of the parties in the event of default in a non-execution auction, there are 2 (two) namely regulated in the ITE law regarding electronic transactions and Consumer Protection which explains the existence of compensation, as well as by taking legal action to resolve disputes, where the parties can choose resolution either through court, arbitration or other alternative dispute resolution institutions (conventional/online dispute resolution) in accordance with the provisions of the Laws and Regulations as the default is related to responsibility.
Kontrol Perilaku Ibu Rumah Tangga Terhadap Penggunaan Tas Belanja untuk Mengurangi Penggunaan Kantong Plastik Terhadap Lingkungan Sekitar
Authors: Melati Deviana
Published: July 2024

The environmental pollution that occurs is increasingly creating awareness on the part of consumers. Wrong One cause of environmental pollution is the use of plastic bags. Use of pockets Plastics that are not environmentally friendly cause environmental damage. Therefore, it is necessary there is a change in the use of inorganic plastic bags to environmentally friendly shopping bags. Changing the use of environmentally friendly shopping bags can reduce the impact of pollution Environment: The aim of this research is to investigate changes in green bags or ecobags Use environmentally friendly shopping bags instead of plastic bags. Environmentally friendly tote bags made from canvas or various types of fabric with designs that have added value and can be folded into a pocket bag, with the addition of batik cloth elements as a medium for preserving Indonesian culture can create added value for both the user and the supplier himself. This idea emerged because of the accumulation of rubbish which is always increasing every day in every part of the world. In Indonesia itself, plastic waste is in the second highest position after food waste. This is based on data in the National Waste Management Information System (SIPSN) in 2021, approximately 15.7% of waste in Indonesia is in the form of single-use plastic. Data from the Indonesian Central Statistics Agency (BPS) in 2018 shows the fact that Indonesia is the second largest contributor of plastic waste in the world. People consume a lot of instant food with plastic packaging, and a lot of it people who have the habit of using plastic bags when carrying out Shopping transactions are the cause of the accumulation of plastic waste in Indonesia.
Perlindungan Hukum Jaminan Kesehatan di Indonesia
Authors: Rahmat Ezravania , Lie Gunardi
Published: July 2024

Social security is an important system in providing adequate protection and access to health services for the community. The most important social security is health insurance. Health insurance is regulated through specific laws and regulations. The implementation of Health Insurance involves the Health Insurance Administering Agency (BPJS) as the one that manages the health insurance program. BPJS is responsible for managing funds, paying claims, setting service rates, monitoring service quality and providing information and education to participants. With the collaboration between BPJS Health and health facilities (Hospitals) through cooperation agreements to ensure access and quality of health services in accordance with established standards. In its implementation related to law enforcement, the effectiveness of the law, public awareness and compliance must be evaluated through several variables of target accuracy, program socialization, achievement of program objectives and implementation monitoring that affect health insurance. The research method used is normative legal research which is descriptive analytical in nature which describes precisely the characteristics of an individual, situation, symptom or particular group and to determine whether or not there is a relationship between a symptom and other symptoms in society. The type of data used is from literature, official documents. The data collection technique used was a literature study with additional interviews from the Health Social Security Administration (BPJS) and one at the hospital. With this health insurance program, some people have registered, but for those who have not registered, BPJS should provide outreach to its participants. In the event that the complaint process is carried out in less days than specified in the regulations.
ROLE OF COVID 19 PANDEMIC ON TALENT MANAGEMENT IN THE INSURANCE SECTOR
Authors: Kajwang Ben
Published: July 2024

Purpose: In the recent years, the insurance industry has experienced accelerated change in technology and uncharted risks in because of the Covid-19 pandemic. This has raised the need for talented employees in the insurance sector who have been a scarce resource in the current business environment. Hence to manage these risks and trends and optimize the value of new technologies, the industry will need a new approach and strategy to attract and retain talent employees in order to improve their performance and remain competitive against their competitors. The purpose of this study was therefore to establish the role of Covid 19 pandemic on talent management in the insurance sector.
Methodology: A desktop literature review was used for this purpose. , a systematic search was carried out using Google Scholar, Semantic Scholar, and Research Gate. The study included relevant sources that were published between 2019 and 2022.
Findings: The study findings indicated that concluded that the revenue reductions and budget shortfalls caused by the COVID-19 crisis have resulted in significant talent management challenges in all industries including insurance firms. Under these difficult circumstances, most organizations have opted to downgrade and even completely abandon performance and talent evaluations and reviews. The fact that these practices are being discontinued demonstrates that many organizations do not implement state-of-the-science talent management systems but, instead, just performance appraisal. In contrast, talent management is particularly suited to address the many talent management challenges created by the COVID-19 crisis because it serves important administrative, strategic and communication, developmental, organizational maintenance, and documentation purposes.  It was also found that measuring results in addition to behaviors, measuring adaptive performance, conducting stay interviews to retain top performers, implementing multisource performance management systems and using performance promoter scores not only help organizations address challenges during a crisis but also allow them to thrive after the crisis is over.
Recommendations: Based on the study findings, the study recommended that insurance firms should foster organizational citizenship behavior. This is because during a time of crisis or pandemic, OCB is important because employees are asked to contribute ideas to help the organization survive, and employees need to go out of their ways to use their talent, skills, networks, and innovativeness to do so. It as well recommended that during a crisis, human resource managers should conduct stay interviews focus on discovering what makes star performers decide to stay in the organization and provide information that managers can use to implement actions that will retain them. -management systems that can be realigned to track skills alongside employee performance.
Unlocking the Potential of Digital Finance for Sustainable Development in Nigeria’s Economy
Authors: Echu Edwin Sunny , Ogundare Nathaniel Jide , Abba Maryam Tijjani , Misau Abdullahi Muhammad , Liman Jaafar Aliyu
Published: July 2024

This study aims to explore the potential of digital finance in driving sustainable development in Nigeria’s economy. The research focuses on defining and highlighting the importance of key constructs related to digital finance. The study also outlines its aims and objectives, which include assessing the impact of digital finance on economic growth, financial inclusion, and financial stability. To achieve these objectives, a positivist approach was adopted, utilizing a sample size of 384 participants. Data analysis was conducted using regression analysis to examine the relationships between digital finance and the desired outcomes. The study also tests three null hypotheses which were all rejected to establish significant associations between digital finance and sustainable development indicators. The technology acceptance model (TAM) served as the underpinning theory for this research, providing a framework to understand users’ acceptance and adoption of digital finance solutions. Additionally, the capability approach theory was used as a supporting theory to explore the role of digital finance in enhancing individuals’ capabilities and well-being. In conclusion, this study shed light on the potential of digital finance in promoting sustainable development in Nigeria’s economy. The findings will contribute to the existing literature on the subject and provide valuable insights for policymakers, financial institutions, and other stakeholders. Based on the research outcomes, the study recommends the adoption and utilization of digital finance to drive sustainable economic growth, financial inclusion, and stability in Nigeria.
A Simulation-based Guided Inquiry Laboratory Package in Teaching Mirrors and Lenses for Grade 10 Learners
Authors: Arboiz Kennette M. , Malayao Jr. Sotero O.
Published: July 2024

The perennial problem of Philippine education characterized by the lack of uniform laboratory apparatus and activities across schools, can be one culprit of low performance in the PISA examinations and ranking. During its conceptualization stage, this study intended to develop a set of activities for optics that allow the guided- inquiry opportunity. A series of evaluation refined the activity to its optimum version and was implemented in a single section in one public school in the Division of Misamis Occidental. Trend of student performance showed that students had a good performance and that the guided inquiry activities helped them in their learning acquisition. The quality of performance task output also showcased the depth of learning acquired by students. The normalized also yielded a medium gain that signifies the guided inquiry virtual activities can engender learning despite the absence of 3- dimensional hands-on laboratory activities.