bluuebunny/crossref_metadata_2025 huggingface dataset:
HUBUNGAN KEBERADAN PENGAWAS MENELAN OBAT DENGAN KEPATUHAN MINUM OBAT PASIEN TUBERKULOSIS DI PUSKESMAS CIMAHI SELATAN KOTA CIMAHI
Authors: Dwi Yulnovianti  , Fardiansyah Mochamad Ari , Karwati
Published: May 2024

Pada tahun 2020, 9,9 juta telah didiagnosis dengan tuberkulosis (TB) dan 1,5 juta tidak mendapat pengobatan TB Salah satu dari delapan negara yang memiliki kasus TB ke dua terbanyak di dunia adalah Indonesia. Pada tahun 2021, terdapat 87 pasien TB di Puskesmas Cimahi Selatan dengan angka kesembuhan hampir 55%. Angka tersebut masih di bawah angka kesembuhan objektif program pengendalian TB nasional minimal 90%. Tujuan penelitian ini untuk mengetahui hasil analisis tentang hubungan keberadaan PMO dengan kepatuhan minum obat pasien TB di Puskesmas Cimahi Selatan. Penelitian ini menggunakan survei analitik Jumlah pasien TB yang telah selesai berobat di Puskesmas Cimahi Selatan antara bulan Januari 2022 sampai Mei tahun 2023 sebanyak 142 orang yang menjadi populasi penelitian ini. Hasil penelitian menunjukan bahwa 87% pasien TB Paru di Puskesmas Cimahi Selatan tidak patuh nenium obat TB, sebagian besar reponden 79(90,8%) memiliki PMO hanya sebagian kecil responden (9,2%) dari yang gagal pengobatan TB di Puskesmas Cimahi Selatan tidak memiliki PMO. Selain itu Sebagian besar 79 responden (90,8%) yang tidak patuh meminum obat TB memiliki PMO TB. Dari hasil analisis didapatan p 0,860 > 0,05 maka Ho diterima. Sebagian besar pasien TB di Puskesmas Cimahi Selatan sebesar 91% pasienmemmiliki PMO, tetapi sebagian besar 87% pasien TB Paru di Puskesmas Cimahi Selatan tidak patuh menjalani terapi TB. Maka dapat disimpulkan tidak ada hubungan antara keberadaan PMO dengan kepatuhan minum obat TB, dengan nilai p=0,860. Disarankan untuk PMO TB supaya dapat meningkatkan kualitas dengan memahami pengetahuan dan dengan aktif mencari informasi tentang pengobatan pasien TB.Kata kunci: Cross-Sectional, Kepatuhan Minum Obat, Keberadaan PMO, Pasien TB.
PENGARUH SENAM HAMIL TERHADAP PENURUNAN NYERI PUNGGUNG PADA KEHAMILAN TRIMESTER III DI PMB "N" KABUPATEN BANDUNG
Authors: Yosi Oktri  , Cantika Lestari  , Nida Amalia Muttaqin
Published: May 2024

Kehamilan merupakan suatu transisi antara kehidupan sebelum dan sesudah kelahiran anak. Perubahan ini dipertimbangkan sebagai periode menjalani proses persiapan baik secara fisik maupun secara psikologi. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh senam hamil terhadap penurunan nyeri punggung pada kehamilan trimester III di PMB "N" Kabupaten Bandung. Penelitian ini menggunakan metode Pre-eksperiment dengan desain penelitian one grup pretest posttest design. Populasi penelitian ini adalah seluruh ibu hamil trimester III. Sampel dalam penelitian ini adalah 10 responden. Nyeri diukur dengan Faces Pain Scale-Revised (FPS-R). Teknik pengambilan sampel menggunakan total sampling. Variabel bebas senam hamil dan variabel terikat penurunan nyeri punggung. Instrumen penelitian menggunakan kuesioner dan observasi. Uji statistik menggunakan uji Wilcoxon . Hasil uji statistik didapatkan adanya penurunan signifikan antara mean intensitas nyeri sebelum dan sesudah diberikan senam hamil dimana p- value 0,004 lebih kecil dari nilai alpha(p<α(0,05), berarti dapat disimpulkan bahwa senam hamil efektif dalam menurunkan intensitas nyeri punggung pada kehamilan trimester III. Hasil penelitian menunjukan terdapat pengaruh senam hamil terhadap ketidaknyamanan nyeri punggung.
Kata kunci : Kehamilan, Nyeri Punggung, Senam Hamil
HUBUNGAN STATUS KELENGKAPAN IMUNISASI DASAR DENGAN KEJADIAN STUNTING PADA USIA ANAK 24 - 59 BULAN
Authors: Ujang Daud  , Susanto Ijun Rijwan , Karwati
Published: May 2024

Masalah malnutrisi yang mendapat banyak perhatian akhir-akhir ini adalah masalah kurang gizi kronis dalam bentuk anak pendek atau stunting. Stunting merupakan keadaan status gizi dimana panjang badan atau tinggi badan menurut umur di bawah standar yang dijadikan parameter. Permasalahan gizi kurang yang dialami dalam waktu lama pada masa pertumbuhan dan perkembangan dari awal kehidupan dapat menunjukkan masalah stunting. Penelitian ini bertujuan untuk mengetahui hubungan status kelengkapan imunisasi dasar dengan kejadian stunting pada anak usia 24 - 59 bulan di wilayah kerja puskesmas Cimahi Selatan kota Cimahi. Rancangan penelitian yang penulis gunakan dalam penelitian ini adalah rancangan penelitian survey analitik jenis Case Control Retropektif. Sampel minimum untuk penelitian ini adalah 41 sampel. Rasio kasus dan kontrol adalah 1:1. Jadi, total sampel menjadi 82 responden, yang terdiri dari 41 kasus dan 41 kontrol. Hasil uji statistik menunujukan nilai p-value 0,208 (> α0,05) berarti dapat disimpulkan tidak terdapat hubungan antara Status Kelengkapan Imunisasi Dasar Dengan Kejadian Stunting Pada Anak Usia 24 - 59 Bulan Di Wilayah Kerja Puskesmas Cimahi Selatan Kota Cimahi. Stunting berpeluang 1,562 kali (95% CI: 0,123 - 1,618) pada balita yang melakukan imunisasi tidak lengkap dibandungkan dengan imunisasi lengkap.
Kata kunci: Stunting, Imunisasi Dasar Anak, Malnutrisi Anak
PENGARUH MEDIA VIDEO ANIMASI VULVA HYGIENE TERHADAP PERILAKU VULVA HYGIENE PADA REMAJA PUTRI DI RW 09 LEUWIGAJAH
Authors: Wahyuni Sri , Rika Afriyani  , Desta Herlia
Published: May 2024

Vulva hygiene yang kurang baik dapat menimbulkan masalah seperti keputihan, iritasi kulit genital, alergi, peradangan, infeksi saluran kemih, hal tersebut berkaitan dengan saluran kemih bawah wanita lebih pendek. Salah satu upaya edukasi yang dapat dilakukan dalam meningkatkan perilaku remaja putri adalah memberikan pendidikan kesehatan melalui media video animasi. Tujuan penelitian ini adalah untuk mengetahui pengaruh media video animasi. Penelitian ini menggunakan desain penelitian quasi eksperimental dengan rancangan one group pretest and posttest without control. Metode pengambilan sampel menggunakan purposive sampling dengan jumlah sampel 35 remaja putri. Hasil penelitian menunjukkan perilaku remaja putri sebelum diberikan video animasi terdapat 16 orang (45,7%) kurang dan 19 orang (54,3%) baik. Kemudian perilaku remaja putri setelah diberikan video animasi terdapat 7 orang (20%) kurang dan 28 orang (80%) baik. Pengukuran dilakukan menggunakan kuisioner sebelum dan setelah diberikan intervensi menggunakan uji McNemer. Hasil uji statistik menunjukkan nilai p value sebesar 0,012 (<0,05), dengan demikian H0 ditolak dan Ha diterima artinya terdapat pengaruh pemberian video animasi vulva hygiene terhadap Perubahan perilaku vulva hygiene pada remaja putri. Bahwa data disimpulkan terdapat pengaruh video animasi vulva vygiene terhadap perubahan perilaku vulva hygiene pada remaja putri di RW 09 Leuwigajah.
KATA KUNCI : Video Animasi, Vulva Hygiene, Perilaku Remaja Putri
Characterization of the Major Ions of Coal Creek Near Cedar City, Utah
Authors: Weaver Jared , Lamb Christopher , Weaver Kim , Kaiser Jason , Redd J Ty
Published: May 2024

The major ions of Coal Creek near Cedar City, in southwest Utah, were measured to determine if there were any differences in ion concentrations in July of 2014 as compared with spring measurements of 2012 and 2013. Past analyses have shown higher ion concentrations in lower regions of Coal Creek despite the apparent lack of water input. This research is aimed to better characterize these abrupt increases in concentration and determine if these trends varied when samples were acquired in the summer vs. in the spring when sample acquisition has occurred in the past. Environmental water samples were collected at evenly spaced locations in Coal Creek from State Route 14 Mile Marker 7 westward to where the creek intersects with Main Street in Cedar City. Ion concentrations were determined in water samples collected every other day for 3 consecutive weeks using Ion Chromatography (IC) and Atomic Absorption Spectroscopy (AA). The spatially intensive sampling revealed two previously unknown low volume springs that are highly concentrated in the major ions and discharge into the creek. Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) was used to characterize trace metal concentrations within the water tributaries, in addition to IC to determine bulk anion content in the creek. The high ion concentrations of springs correlated well with known geologic features near the creek, such as faulted gypsum layers creating springs as well as evaporate deposits, both of which explain the doubling of ion concentrations seen in the examined section of Coal Creek.
Triple-Level Single-Ended Main Inductor Converter (SeMLC) with regard to Wind-Solar Hybrid Energies
Authors: Jaenul Ariep , Altameemi Ban Najm Abdullah
Published: May 2024

An output from a DC-to-DC converter that can be more or less than its input is called a Single-Ended Main Inductor Converter (SeMLC). Nevertheless, there is more switching stress in this dual-level SEMIC, which raises switching losses. This rise in switching loss causes the power converter's efficiency to drop. This research suggests a Triple stage SeMIC with lower switching losses to get over this drawback. Using a lower rated switch, Triple level SEMIC increases power efficiency. There is a description of a control method that balances the voltage of the capacitor to avoid damaging the power switch. The suggested converter also lessens the ripple in inductor current in the output inductor. Triple level SeMIC uses a hybrid wind-solar energy system as a source. The benefits of the suggested converter are emphasized by discussing the simulation results of both dual- and Triple-level SeMIC.
INVESTIGATION OF THE EFFECT OF SMALL THERMAL NEUTRON FLUXES ON THE PROPERTIES OF BACTERIA RHIZOBIUM PHASEOLI IS TAAS-80 TJ AND BACILLUS MEGATERIUM VAR. PHOSPHATICUM
Authors: Makhsudov Barot Islomovich , Habibulloev Hamidullo , Nigorai Zaydullo
Published: May 2024

In this work, the effects of a small thermal neutron flux on the growth rate of Rhizobium phaseoli IS TAAS-80 TJ and Bacillus megaterium var. phosphaticum bacteria intended for use in the production of micronutrients were studied. The phenomenon of germination of grow rate of bacteria under irradiation with small fluxes of thermal neutrons has been discovered. The best result was obtained with thermal neutron fluxes of 5.4-106 Fluence, at which the grow rate of bacteria increases by 5-6 times.

It has been experimentally shown that one of the possible mechanisms of the influence of thermal neutrons on the properties of biological objects is the interaction of thermal neutrons by the nuclei of light atoms of the composition of these objects. For this purpose, the IR spectra of the bacteria Rhizobium phaseoli IS TAAS-80 TJ and Bacillus megaterium var. phosphaticum were studied and the effect of a small thermal neutron flux on the spectral characteristics of these bacteria was estimated. It was found that in some bands of the IR spectrum of bacteria, when they are irradiated with small fluxes of thermal neutrons, the optical density intensity ratio changes. The greatest change is observed with thermal neutron fluxes of 5.4-106 Fluence, which correlates with an increase in the growth rate of bacteria by 5-6 times. It has been established that the change in the biological activity of bacteria is associated with a change in methyl groups.

It has been experimentally shown that one of the possible mechanisms of the influence of thermal neutrons on the IR spectrum of the bacteria Rhizobium phaseoli IS TAAS-80 TJ and Bacillus megaterium var. phosphaticum is a nuclear reaction of radiation capture of thermal neutrons by nuclei of nitrogen atoms of the species .

It is assumed that the mechanism of changing the activity of bacteria under the influence of thermal neutrons is due to a change in the conformation of DNA chains at certain sites and methylation of DNA, proteins and polymerase.
PATTERN OF SUICIDE DEATHS: A RETROSPECTIVE 5-YEAR AUTOPSY SAMPLE ANALYSIS IN PAKISTAN
Authors: Imran Nazish , Tariq Fareeha , Bhatti Izwa , Tariq Summaiya Syed , Ali Riasat , EhsanUllah Hafsah
Published: May 2024

Objective:
Suicide is a global public and mental health problem. In this study, we evaluated autopsy reports of suicidal deaths for 5 years to study the demographic distribution of the suicide victims, and methods of suicides.
Methods:
It is a descriptive cross-sectional study of suicide autopsies conducted at the mortuaries of two large Forensic departments in Punjab and Sindh (King Edward Medical University/Mayo hospital, Lahore, and Jinnah Postgraduate Medical Centre Karachi) for 5 years, between January 2017-December 2021. Data was collected on pre-designed proformas and was statistically analysed using SPSS 26.
Results:
Between 2017 and 2021, 98 cases of suicide were examined in the two study centres (67 males ,68.4% and 31 females, 31.6 %). Fifty-six suicides (57%) were in age group under 30 years old. The most frequently used methods for suicide were hanging (41,41.8%) , use of firearms (23, 23.5%), Self-poisoning (11,11.2%), and jumping from heights (6, 6.1%). Significant differences were noted regarding method of suicide among gender and different age groups as well as different study centres (P value<.05). Firearms were used solely by males, and all deaths due to jumping from heights were in Karachi.
Conclusion:
Due to local cultural and religious beliefs, the autopsy rate in suicide seems too low. There was a male preponderance amongst suicidal death autopsies in our study sample. Hanging  Firearms and self-poisoning were the most frequent suicidal methods. Provision of psychological and social supports along with restriction to easy access to firearms and poisons should be considered by policy making and healthcare authorities to tackle this preventable public health problem.
MODERN KAZAKH NOVEL: PAINTING AND AESTHETICS OF ARTISTIC DECISION OF THE XX CENTURY
Authors: Ashimkhan Taldaubek
Published: May 2024

The author of the article sets herself a goal – to highlight the relationship between Turkic-speaking and Iranian-speaking poets of the 15th–16th centuries, recorded in the “Tarikh-i Rashidi” by Mirza Muhammad Haidar. This question is poorly understood. This is proved the novelty of the idea of research. The article, written on the basis of data from a medieval source, helps to expand the relationship in Central Asian literary circles, a genre of poetry that was popular during this period. The picture of the relationship of poets is one of the aspects of the relationship in the culture of the peoples of Central Asia. The researcher used the publication “Tarikh-i Rashidi”, carried out by source scholars of Uzbekistan. As a result of the analysis of data from this work, it was established that the muʻamma genre was quite popular during the study period. The names of the masters of compiling charades, works on this genre are given. The data of “Tarikh-i Rashidi” were compared with data from “Majalis an-Nafais” by ʻAli Shir Navaʻi. It is established that some young poets of the era of ʻAli Shir Nava’i by the time of writing “Tarikh-i Rashidi” became famous poets in Herat. In the cultural center of Khorasan – Heart, poetry developed along with treatises. The relationship between the poets of Herat circle proves the path of development of the literature of Iranian-speaking and Turkic-speaking peoples of Central Asia, being an indicator of the relationship in the culture of the peoples of studying region.
CONTINUITY IN POLITICAL AUTHORITY OF THE PRC: FEATURES OF THE FIRST GENERATION FOREIGN POLICY
Authors: Dalelkhan Aibolat
Published: May 2024

The issue of succession to political power in the People's Republic of China is a frequently discussed topic in academic research. The fifth generation of Chinese power, the Xi Jinping administration, without opposing the political views of previous generations, continues its political course adhering to the basic foreign policy principles since the time of Mao Zedong. Therefore, the issue of continuity of China's foreign policy concepts is of particular interest. The main goal of the work is to consider the conceptual foundations of the foreign policy of the first generation of Chinese power and its evolution of development associated with changes in international relations of that time. The novelty of the study lies in the fact that foreign policy concepts formed during the time of Mao Zedong create optimal conditions for rationalizing the foreign policy of today's China. Objectives include assessing certain historical events in Chinese foreign policy and diplomacy and determining how they influenced the subsequent development of Chinese foreign policy. The research topic was considered based on the theory of political realism using methods of historical-comparative, structural, content analysis, and systematization methods. These methods helped to consider the problem and systematize the research results comprehensively. The results of the study provide an opportunity to deeply understand the issues of succession of Chinese political power and China's current foreign policy positions in a historical context. In addition, the results of the study can be widely used in research in the field of international relations, political science, Chinese studies, and history.
How a Christian Worldview Defines Strategy
Authors: Salgado Leonidas
Published: May 2024

Strategic decision makers have a set of beliefs, a worldview, that frame what reality is for them. Using this framework, they set strategic goals which, in turn, form a set of primary actions that define the strategic options of the firm. Therefore, we should be able to recognize various schools of strategy as defined by distinctive sets of beliefs in theory and practice. The paper argues that this is the case and that we should then be able to define at least one possible Christian school of strategy, framed by a Christian set of beliefs. A Christian school of strategy should assist all strategists in achieving their purposes in ways that are lifeenhancing for their organizations.
Proverbs: Ancient Wisdom for Contemporary Organizations
Authors: Dose Jennifer J.
Published: May 2024

This article discusses how the Biblical Book of Proverbs applies to contemporary organizations. An inductive study of the Proverbs related to organizational life elicited a set of thematic categories. All proverbs related to these categories are reported, and a subset of these categories is explored further. Select examples of proverbs are provided to illustrate each topic with connections made to current management scholarship. Finally, these topical themes are integrated in the context of organizational trust, demonstrating the importance of comprehensive adherence by organizations and their members to all the principles that Proverbs advocates. The degree to which all of the themes within Proverbs are present in organizational trust highlights the significance of God's wisdom for organizational relationships and effectiveness.
Management: A Faith-Based Perspective, by Michael E. Cafferky
Authors: Edgell Margaret
Published: May 2024

This review is of a management textbook, so any evaluation of the book must address whether or not it is appropriate for adoption in a management course. I enthusiastically recommend Management: A Faith-Based Perspective for adoption, particularly in Introduction to Management. It lays a sure foundation of Christian perspectives for the rest of the business curriculum.
Analisis Sumber Dana Pendidikan SMKS St.Nahanson Parapat Sipoholon
Authors: Rapita Banjarnahor Rapita , Hotmarito Hutabarat  , Tia Murni Tampubolon  , Rico Sihotang  , Tetti Manullang
Published: May 2024

Untuk meningkatkan kualitas pendidikan yang diharapkan, dana yang memadai sangat penting untuk mendukung berbagai aspek pembiayaannya. Kualitas pendidikan tidak dapat ditingkatkan tanpa adanya alokasi sumber daya keuangan yang cukup. Penelitian ini dilakukan di SMKS St. Nahanson Parapat dengan tujuan utama untuk mengidentifikasi sumber-sumber pendanaan yang digunakan oleh lembaga ini. Memahami sumber pendanaan dianggap krusial dalam manajemen lembaga pendidikan untuk mencapai tujuan pendidikan yang diinginkan.Metodologi yang digunakan dalam penelitian ini adalah pendekatan kualitatif, yang melibatkan teknik observasi, wawancara, dan dokumentasi untuk mengumpulkan data. Data utama diperoleh melalui wawancara dengan kepala sekolah, yang memberikan informasi mengenai sumber-sumber dana yang tersedia di SMKS St. Nahanson Parapat Sipoholon.Pendanaan pendidikan adalah tanggung jawab bersama antara pemerintah, pemerintah daerah, dan masyarakat, dan harus dikelola dengan prinsip keadilan, kecukupan, dan keberlanjutan. Efisiensi, transparansi, dan akuntabilitas publik juga merupakan prinsip penting dalam pengelolaan dana pendidikan. Sumber dana ini sangat menentukan dalam efektivitas dan efisiensi manajemen pendidikan.Sumber-sumber dana pendidikan untuk SMKS St. Nahanson Parapat meliputi: 1) Bantuan Operasional Sekolah (BOS) dari Pemerintah Pusat, 2) Iuran SPP dari Peserta didik, 3) Yayasan SMKS St. Nahanson Parapat, dan 4) kontribusi dari para alumni yang terlibat dalam berbagai kegiatan, termasuk bantuan finansial maupun fasilitas. Besaran biaya pendidikan sangat terkait erat dengan kualitas pendidikan yang diberikan, termasuk layanan kepada siswa dan kebersihan sekolah.Hasil dari penelitian ini menunjukkan bahwa prinsip-prinsip pengelolaan sumber dana yang ada dalam teori telah berhasil diterapkan di SMKS St. Nahanson Parapat Sipoholon. Hal ini terlihat dari kesesuaian antara teori dan praktik di lapangan terkait dengan sumber-sumber dana pendidikan. Temuan ini diharapkan dapat memberikan wawasan kepada kepala sekolah dalam menentukan dan mengelola sumber-sumber dana sekolah, memastikan bahwa mereka memiliki pemahaman yang mendalam tentang sumber-sumber pendanaan yang tersedia untuk lembaga pendidikan mereka.
The relationship between gluten proteins and loaf volume
Authors: Knežević Desimir , Kondić Danijela , Dragovich Aleksandra. Yu. , Kudryavtsev Alexander M. , Matković Stojšin Mirela , Zečević Veselinka , Radosavac Adriana , Paunović Aleksandar
Published: May 2024

The storage proteins influence technological quality value of grain wheat, dough quality traits, and loaf quality. The aim of this study is to estimate variability in the dry gluten content, loaf volume, and their relationships with encoding alleles of gliadin and glutenins. Wheat genotypes grown in two vegetation seasons (2015/16 and 2016/17) were studied. The technological quality traits analyzed in this study varied in wheat genotypes within and between vegetation seasons. In both vegetation seasons the highest dry gluten content was established in G-3621-1 (30.23% and 31.15%) and the highest value of loaf volume in G-3621-1 (530 ml and 540 ml). In both vegetation seasons the least dry gluten content was found in G-3606-6 (25.42% and 25.98%) and the least loaf volume in G-3606-6 (380 ml and 390 ml). The composition of gliadin and glutenin alleles in the wheat genotypes analyzed was different. The genotypes carrying Gli-B1b, Gli-D1b, Gli-D2b, and Glu-A1b, Glu-B1c, Glu-D1d had the highest gluten content, while the genotype that carried Gli-B1l and Glu-A1b, Glu-B1c, Glu-D1d had high bread volume. The results have shown relationships between gliadin and glutenin alleles and quality traits of grain, flour, and bread.
Przejawy mineralizacji kruszcowej w skałach obszaru Strzelin–Głuchołazy
Authors:   Państwowy Instytut Geologiczny – Państwowy Instytut Badawczy, Markowiak Marek
Published: May 2024

Na podstawie badań mikroskopowych i w mikro­obszarze próbek skał z trzech rejonów morawsko-śląskiej strefy tektonicznej: Wzgórz Strzelińskich, okolic Paczkowa i Głuchołaz, dokonano charakterystyki przejawów mineralizacji kruszcowej tego obszaru. Stwierdzono obecność szerokiego zestawu minerałów kruszcowych, w tym wielu dotychczas na badanym obszarze nierozpoznanych, takich jak: piryt, pirotyn, chalkopiryt, sfaleryt, mielnikowit, mielnikowit-piryt, markasyt, kowelin, digenit, galena, greenockit, carrolit-fletscheryt, bravoit, Co-bravoit, molibdenit, scheelit, tennantyt, minerały z grupy euksenitu (EGM) zbliżone do yttrocrasite-(Y), elektrum, bizmut rodzimy, bismutynit, cosalit, joseit?, tsumoit?, gustavit?, stannin, argentyt, srebro rodzime, ilmenit, rutyl, tytanit, goethyt oraz szereg minerałów pierwiastków promieniotwórczych – uraninit, toryt, coffinit, a także minerałów zawierających pierwiastki promieniotwórcze (w tym wspomniane wyżej minerały grupy euksenitu): rabdofan, uranopolycrase i prawdopodobnie thorbastnäsyt współwystępujący z parisytem. Zespołem mineralnym najpowszechniej spotykanym w całym regionie jest zespół o składzie: piryt, pirotyn, chalkopiryt, sfaleryt, przy czym dwa ostatnie minerały występują podrzędnie. Przejawy mineralizacji pierwiastkami ziem rzadkich wymagają dalszych badań w pierwszej kolejności.
LITOSTRATYGRAFIA OSADÓW WYŻSZEJ CZĘŚCI NEOGENU NA OBSZARZE NIŻU POLSKIEGO
Authors:   Państwowy Instytut Geologiczny – Państwowy Instytut Badawczy, Kasiński Jacek , Słodkowska Barbara ,   Państwowy Instytut Geologiczny – Państwowy Instytut Badawczy
Published: May 2024

W pracy główny nacisk położono na prezentację i dyskusję na temat korelacji osadów wyższej części neogenu na Niżu Polskim. W rezultacie zaproponowano nowy podział litostratygraficzny lądowych osadów wyższego neogenu w basenie niżowym. Skorygowano dane i nazewnictwo, dotyczące dotychczas stosowanych jednostek litostratygraficznych oraz wykreowano i zrewidowano kilka jednostek, które skorelowano z aktualnym podziałem chronostratygraficznym dla obszaru Europy. Zastosowano zasady podziałów litostratygraficznych zgodnie z litologicznymi kryteriami przyjętymi przy tworzeniu nowych jednostek litostratygraficznych. Ważnym zadaniem było ustalenie pozycji stratygraficznej utworów wyższej części miocenu i pliocenu ze szczególnym uwzględnieniem serii brunatnowęglowych oraz rozdzielających je osadów mineralnych. Ramy czasowe weryfikowanego odcinka neogenu są zdefiniowane przez dwa regionalne zdarzenia geologiczne, które zaznaczyły się niemal na całym obszarze Niżu Polskiego: dolną granicę badanego interwału definiuje początek sedymentacji charakterystycznych piasków adamowskich i tworzenia się węgla brunatnego I pokładu środkowopolskiego, a górną granicę stanowi początek glacjacji plejstoceńskiej. Na przeważającym obszarze Niżu Polskiego, poza Polską południowo-zachodnią, profil osadów wyższego neogenu jest na ogół pełny, z niewielką liczbą luk stratygraficznych, chociaż jest widoczne pewne zróżnicowanie regionalne osadów. Jest to spowodowane nieco odmiennym reżimem sedymentacyjnym, stymulowanym najczęściej zmianami geotektonicznymi i związanymi z nimi oscylacjami klimatu. Utwory wyższego neogenu na obszarze Niżu Polskiego są w przeważającej mierze osadami lądowymi, wykształconymi w facjach fluwialnych, limnicznych i telmatycznych.
Inferring control objectives in a virtual balancing task in humans and monkeys
Authors: Sadeghi Mohsen , Sharif Razavian Reza , Bazzi Salah , Chowdhury Raeed H , Batista Aaron P , Loughlin Patrick J , Sternad Dagmar
Published: May 2024

Natural behaviors have redundancy, which implies that humans and animals can achieve their goals with different strategies. Given only observations of behavior, is it possible to infer the control objective that the subject is employing? This challenge is particularly acute in animal behavior because we cannot ask or instruct the subject to use a particular strategy. This study presents a three-pronged approach to infer an animal’s control objective from behavior. First, both humans and monkeys performed a virtual balancing task for which different control strategies could be utilized. Under matched experimental conditions, corresponding behaviors were observed in humans and monkeys. Second, a generative model was developed that represented two main control objectives to achieve the task goal. Model simulations were used to identify aspects of behavior that could distinguish which control objective was being used. Third, these behavioral signatures allowed us to infer the control objective used by human subjects who had been instructed to use one control objective or the other. Based on this validation, we could then infer objectives from animal subjects. Being able to positively identify a subject’s control objective from observed behavior can provide a powerful tool to neurophysiologists as they seek the neural mechanisms of sensorimotor coordination.
Microtubule-dependent orchestration of centriole amplification in brain multiciliated cells
Authors: Boudjema Amélie-Rose , Balagué Rémi , Jewett Cayla E , LoMastro Gina M , Mercey Olivier , Jord Adel Al , Faucourt Marion , Schaeffer Alexandre , Noûs Camille , Delgehyr Nathalie , Holland Andrew J , Spassky Nathalie , Meunier Alice
Published: May 2024

Centriole number must be restricted to two in cycling cells to avoid pathological cell divisions. Multiciliated cells (MCC), however, need to produce a hundred or more centrioles to nucleate the same number of motile cilia required for fluid flow circulation. These centrioles are produced by highjacking cell cycle and centriole duplication programs. However, how the MCC progenitor handles such a massive number of centrioles to finally organize them in an apical basal body patch is unclear. Here, using new cellular models and high-resolution imaging techniques, we identify the microtubule network as the bandleader, and show how it orchestrates the process in space and in time. Organized by the pre-existing centrosome at the start of amplification, microtubules build a nest of centriolar components from which procentrioles emerge. When amplification is over, the centrosome’s dominance is lost as new centrioles mature and become microtubule nucleators. Microtubules then drag all the centrioles to the nuclear membrane, assist their isotropic perinuclear disengagement and their subsequent collective apical migration. These results reveal that in brain MCC as in cycling cells, the same dynamics - from the centrosome to the cell pole via the nucleus-exists, is the result of a reflexive link between microtubules and the progressive maturation of new centrioles, and participates in the organized reshaping of the entire cytoplasm. On the other hand, new elements described in this work such as microtubule-driven organization of a nest, identification of a spatio-temporal progression of centriole growth and microtubule-assisted disengagement, may shed new light on the centriole duplication program.
Inhibition of ULK1/2 and KRASG12C controls tumor growth in preclinical models of lung cancer
Authors: Ghazi Phaedra C , O'Toole Kayla T , Srinivas Boggaram Sanjana , Scherzer Michael T , Silvis Mark R , Zhang Yun , Bogdan Madhumita , Smith Bryan D , Lozano Guillermina , Flynn Daniel L , Snyder Eric L , Kinsey Conan G , McMahon Martin
Published: May 2024

Mutational activation of KRAS occurs commonly in lung carcinogenesis and, with the recent U.S. Food and Drug Administration approval of covalent inhibitors of KRASG12C such as sotorasib or adagrasib, KRAS oncoproteins are important pharmacological targets in non-small cell lung cancer (NSCLC). However, not all KRASG12C-driven NSCLCs respond to these inhibitors, and the emergence of drug resistance in those patients who do respond can be rapid and pleiotropic. Hence, based on a backbone of covalent inhibition of KRASG12C, efforts are underway to develop effective combination therapies. Here, we report that the inhibition of KRASG12C signaling increases autophagy in KRASG12C-expressing lung cancer cells. Moreover, the combination of DCC-3116, a selective ULK1/2 inhibitor, plus sotorasib displays cooperative/synergistic suppression of human KRASG12C-driven lung cancer cell proliferation in vitro and superior tumor control in vivo. Additionally, in genetically engineered mouse models of KRASG12C-driven NSCLC, inhibition of either KRASG12C or ULK1/2 decreases tumor burden and increases mouse survival. Consequently, these data suggest that ULK1/2-mediated autophagy is a pharmacologically actionable cytoprotective stress response to inhibition of KRASG12C in lung cancer.
Book Review of: Ramadani, V., Kjosev, S. and Sergi, Bruno S. (2023). Entrepreneurship Development in the Balkans: Past, Present, and Future
Authors: Chichevaliev Stefan
Published: May 2024

Book Review of: Ramadani, V., Kjosev, S. and Sergi, Bruno S. (2023). Entrepreneurship Development in the Balkans: Past, Present, and Future
Geographic Accessibility of General Practitioners by Car and Public Transport - A Study Using the Minimum Travel Time Method in a Rural Area in the North-East of Germany
Authors: Hecht Julia , Langer Bernhard
Published: May 2024

Basic medical care should be accessible to all people without restriction. However, the distribution of practices in rural areas is often limited to the centers, meaning that distances have to be covered. The Federal Joint Committee (G-BA), the highest decision-making body of the joint self-government of physicians, dentists, hospitals and health insurance funds in Germany, only states for cars that 95% of the population should be able to reach general practitioners (GPs) in less than 20 minutes on average. The aim of this study was to determine the geographic accessibility of GP practices by car and public transport.
A cross-sectional study was conducted in a rural area in the north-east of Germany called Neustrelitz Central Zone and reported according to the STROBE statement. Geographic data of OpenStreetMap and the Federal Agency for Cartography and Geodesy and GP practices data of the Associations of Statutory Health Insurance Physicians Mecklenburg-Western Pomerania and Brandenburg were used. Based on the method of minimum travel time, the required travel times by car and public transport from the local centers to the three nearest physician locations were determined using various online tools.
On average, inhabitants need 10.7 minutes to reach the three nearest GP practices by car, up to a maximum of 19 minutes. The average travel time by public transport for an appointment at 10 a.m. is four hours and twelve minutes. While it is possible for all municipalities (and their inhabitants) to reach the nearest GP practices in time for an appointment at 10 a.m. and to complete the return journey on the same day, this is no longer possible for 35% of municipalities (and their inhabitants) for an appointment at 3 p.m. and for 53% for an appointment at 5 p.m.
In the Neustrelitz Central Zone, the accessibility of GP practices by car is ensured in accordance with the G-BA statements. On the other hand, the accessibility of GP practices by public transport can be a problem for people who do not have their own car. This could be remedied, for example, by expanding eHealth or mobile medical practices.
Performance of ZZ (Zamioculcas zamiifolia) Cultivars on Different Organic Potting Mixture
Authors: `Sangloi . , Keditsu Rokolhuü , M Abdul Rahman
Published: May 2024

An experiment was carried out at the research cum instructional farm, Department of Horticulture, School of Agricultural Sciences, Nagaland University, Medziphema, India (2022-2023). The experiment was laid out in completely randomized design (CRD) with 14 treatments and 3 replications. The treatments consisted of organic substrates (T1: FYM, T2: Vermicompost, T3: Used tea leaves, T4: Forest litter, T5: Cocopeat, T6: Perlite and T7: Rice husk) and 2 cultivars (C1: Super Nova and C2: Black Raven). The rooted plants of ZZ cultivars were planted in different organic substrates along with garden soil and sand in the ratio of 1:1:1. Among the cultivars, C1 (Super Nova) was found to be significantly better than Black Raven. Amongst the organic substrates, T5 (Garden soil + sand + cocopeat) was found to be statistically superior in all observed parameters except for plant height which was found to be in maximum in T4 (Garden soil + sand + forest litter). The same treatment of T5 exhibited the highest profit (Rs. 12250) and benefit cost ratio (1.89) on ZZ cultivar Black Raven.
A Critique of Supervisory Practices of Doctoral Student Research in Emerging Higher Education Context, Botswana
Authors: Dube Buyisani
Published: May 2024

The science community in Botswana holds a broad consensus that not enough quality PhDs are being produced to meet the needs of societal developments in the country. There appears to be a connection between the level of knowledge advancement of a nation and its economic wealth. The role of supervision in the quest for a leap towards quality and quantity knowledge output therefore, cannot be overemphasised. This paper provides a critique of supervisory practices of doctoral student research in emerging higher education context of Botswana. The study adopted a desk top research methodology which focused on a scoping view of studies related to the phenomenon of study. The areas interrogated included the initial stage of student recruitment and selection, allocation of supervisors, proposal development, and management environment for research, implementation of the proposal, and document compilation for examination.
A History of International Engagement in the Council for Exceptional Children Since 1980. Part 1: Organizational Components
Authors: Keller Clayton , Martin Suzanne
Published: May 2024

Is the Council for Exceptional Children (CEC), arguably the largest professional organization in exceptional education in the world, international or not? What does it mean to be international? An integrative literature review of primary sources of CEC news articles, reports of initiatives and workgroups, and columns in CEC publications that provided records of the Council’s internationally related thinking and activities involving countries outside the United States and Canada was conducted to reconceptualize CEC’s international nature since 1980. In this article, we report the findings from these sources that provide evidence of international aspirations and activities at times for six organizational components of CEC—mission and vision, policy, units, committees, work groups, and membership. There were instances of international thinking and efforts in these components. Both are necessary for meaningful international engagement, as neither is sufficient on its own. Our results suggest, though, that each may have been wanting. Recommendations are provided on how CEC can increase its global engagement through these elements.
ChemInform Abstract: Synthesis and Crystal Structure of Ba2ScCl7, a Barium Chloride Hexachloroscandate(III), Ba2Cl[ScCl6].
Authors: MASSELMANN S. , MEYER G.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Na3AsSe3 and K3AsSe3 — Synthesis and Crystal Structure.
Authors: BRONGER W. , DONIKE A. , SCHMITZ D.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Spectroscopic Properties of LiErF4.
Authors: HEYDE K. , BINNEMANS K. , GOERLLER‐WALRAND C.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Eu1‐xPrxBa2Cu3 O7‐δ Solid Solutions.
Authors: GLUSHKOVA V. B. , KRZHIZHANOVSKAYA V. A. , EGOROVA O. N. , LAPSHIN A. E. , ZAITSEV YU. M.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Improved Porous Mixture of Molybdenum Nitride and Tantalum Oxide as a Charge Storage Material.
Authors: DENG C. Z. , PYNENBURG R. A. J. , TSAI K. C.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Phase Diagram of the Indium—Tellurium System.
Authors: BUDANOVA N. YU. , SKASYRSKAYA E. YA.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of LiMnO2 with α‐NaMnO2‐Type Structure by a Mixed‐Alkaline Hydrothermal Reaction.
Authors: TABUCHI M. , ADO K. , KOBAYASHI H. , KAGEYAMA H. , MASQUELIER C. , KONDO A. , KANNO R.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Preparation of Fibrous, Porous Hydroxyapatite (HAp) Ceramics from Hydroxyapatite Whiskers.
Authors: SUCHANEK W. L. , YOSHIMURA M.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: B4 Tetrahedra for Aluminum Atoms — A Surprising Substitution in τ‐Borides Ni20Al3B6 and Ni20AlB14.
Authors: HILLEBRECHT H. , ADE M.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Analysis of Substituent Effects on 1H and 13C NMR Parameters of Substituted Furans. Linear Free Energy Relationships and PM3 Semiempirical Calculations.
Authors: ALVAREZ‐IBARRA C. , QUIROGA‐FEIJOO M. L. , TOLEDANO E.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ecstasy: 3,4‐Methylenedioxymethamphetamine (MDMA).
Authors: MORIMOTO B. H. , LOVELL S. , KAHR B.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Effect of 3‐Substitution on the Structures of Pyrrole‐2‐carbaldehydes.
Authors: DESPINOY X. L. M. , HARRIS S. G. , MCNAB H. , PARSONS S. , WITHELL K.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 13C NMR Study on Magnesium Carbenoids.
Authors: SCHULZE V. , LOEWE R. , FAU S. , HOFFMANN R. W.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoelectronic Effect at Nitrogen in 2,6‐Di‐tert‐butyl‐4‐(N,N‐disubstituted‐aminomethyl)phenoxyl Radicals (I) and (II).
Authors: JAEGER M. , STEGMANN H. B.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Effect of an Alkoxy Group on the Kinetic and Thermodynamic Acidity of Benzene and Toluene.
Authors: SCHLOSSER M. , MACCARONI P. , MARZI E.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Ligands for Regio‐ and Enantiocontrol in Pd‐Catalyzed Allylic Alkylations.
Authors: PRETOT R. , PFALTZ A.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of P‐Chiral, Non‐Racemic Phosphinylacetates via Enzymatic Resolution of Racemates.
Authors: KIELBASINSKI P. , ZURAWINSKI R. , PIETRUSIEWICZ K. M. , ZABLOCKA M. , MIKOLAJCZYK M.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Synthesis of peri‐Hydroxy Aromatic Compounds: A Strong Base‐Induced [4 + 2] Cycloaddition of 4‐Phenylthio‐Substituted Homophthalic Anhydrides with Various Sulfinyl‐Substituted Dienophiles.
Authors: KITA Y. , IIO K. , OKAJIMA A. , TAKEDA Y. , KAWAGUCHI K. , WHELAN B. A. , AKAI S.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Pentafluorophenol: A Superior Reagent for Condensations in Heterocyclic Chemistry.
Authors: RAJAPPAN V. P. , HOSMANE R. S.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Polyfluoroalkylated 1,4‐Diazinols and 1,4‐Oxazinols Using Polyfluoro‐2,3‐epoxyalkanes.
Authors: SALOUTINA L. V. , ZAPEVALOV A. YA. , KODESS M. I. , SALOUTIN V. I.
Published: July 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.