bluuebunny/crossref_metadata_2025 huggingface dataset:
Manage Waste organic with Bioconversion Black Soldier Fly on Business Mega Maggot
Authors: Nathaniela Thalea Christy , Pramono Andi , Nurwardani Sekar Arum , Gunawan Alan Lukito , Adhirajasa Mahaputra Daffa
Published: November 2023

Management waste in developing countries is causing environmental concerns, particularly food waste. The study explores the use of the Black Soldier Fly (BSF) in managing organic waste and food waste in the business of Mega Maggot. The research aims to promote BSF as a potential and economical alternative to recycling biological waste. The study also discusses the challenges faced in changing the traditional feed model for maggot production, which relies on factory-made or subsidized feed. The authors utilized the Classic Life Cycle to create Mega Maggot’s website, a sequential software development process that minimizes errors and allows for easy modifications during testing. This method ensures accurate results and publishability. The author created a prototype website for Mega Maggot, serving as an informative learning media and purchasing platform for products and services. Activity diagrams on this website illustrate users as companies, individuals, and agents. This website offers a user-friendly interface with an earth-tone base color and sufficient fonts. Users can perform various activities, including purchasing menus and accounts. The Mega Academy offers three programs: Mega classes, workshops, and visits, focusing on waste management, organic waste management, and BSF breeding. The company also provides products like fresh, dried, and organic fertilizers.
Growth Response and Results of Two Sorgum Varieties With Different Dosage Application of Arbuscular Mycorrhizal
Authors: Mawardhani Munti’ah , Harsono Puji , Supriyono
Published: November 2023

Sorghum is an adaptive plant, able to grow and develop on sub-optimal land such as dry land but the soil fertility level is still low. This study aims to determine the variety of sorghum and the appropriate dosage of arbuscular mycorrhizal fungi (AMF) for growing sorghum on dry land and to determine the best interaction effect. Research is carried out in the field and in the laboratory. The environmental design used was a complete randomized block design with two factorials and was repeated three times. The first factor was 2 varieties of sorghum namely Luzhouhong (V1) and Hongyingzi (V2). The second factor was the dose of AMF at a dose of 0 g/plant (D0), 2.5 g/plant (D1), of 5 g/plant (D2), 7.5 g/plant (D3). The results showed that the sorghum variety that had more potential to be developed on dry land based on growth and yield variables was the luzhouhong variety. The right dose of AMF for growth and yield on dry land is a dose of 2.5 g/plant (D1) compared to other AMF doses. The combination of Luzhouhong sorghum varieties with AMF dose of 2.5 g/plant is suitable for development in dry land as a result of seed production.
Effects of Milling Time on Nano Rice Husk Ash Particle Size
Authors: Nasser Ibrahim Mohammed , Wan Ibrahim Mohd Haziman , Mohd Zuki Sharifah Salwa , Alshalif Abdullah Faisal , Nindyawati Nindyawati , Jaya Ramadhansyah Putra
Published: November 2023

This research focuses on the manufacture of nano Rice Husk Ash (nRHA) by ball milling technique and critically analyzes the effect of milling time on particle size. The process starts with collection of raw rice husk from a local rice mill factory, followed by controlled incineration at a temperature of 700°C for 5 hours to get the amorphous RHA. Finally, the nano RHA is prepared by subjecting the RHA to grinding for the different period like 10, 20, 30, and 40 hrs. The particle size was analyzed with FESEM, and it was found that particles got smaller as grinding proceeded, reaching an optimal size of 28 nm following 30 h grinding. Nonetheless, prolonged grinding resulted into particle agglomeration that was caused by Van der Waal forces. Therefore, these findings are significant in that they help to comprehend the morphology changes and particle size alterations in nRHA that may be applied for different uses such sustainable construction materials.
User’s Perception of Indoor Air Quality (IAQ) in Tall Office Buildings as the Cause of Symptoms of Sick Building Syndrome
Authors: Hajji Apif M. , Natasya Nasta , Malta Viola
Published: November 2023

The user’s assessment or perception of indoor air quality (IAQ) refers to an individual’s subjective assessment or perception of the quality of the air they breathe inside a particular building or space. This assessment or perception is very individual and can vary from one individual to another. This study aims to determine the IAQ felt by users of the Rectorate Building, State University of Malang, and its effect on Sick Building Syndrome (SBS) symptoms. This research is included in the quantitative research with the study population being all employees at the building, which has 215 people. The data collection technique in this study used the MM040NA questionnaire and the data analysis technique used was binary logistic regression analysis with the help of the IBM SPSS Statistics with crosstabs test. The results of this study indicate that all independent variables have no significant relationship with SBS symptoms experienced by respondents and all independent variables have a very weak correlation. In addition, from 80 respondents, 27 people (33.75%) experienced SBS and 53 people (66.25%) did not experience SBS. This shows that there is a SBS phenomenon in the building. The significance value for all independent variables is greater than the significance level value (>0.05). Furthermore, based on the test criteria, it is concluded that the variable airflow, high temperature, temperature change, low temperature, stale air, dry air, odor, air electrostatics, cigarette smoke, sound level, lighting, and air pollution have approximate significance values greater than 0.05 (null hypothesis was failed to be rejected). It is concluded that those variables have no significant relationship to the dependent variable (the SBS symptoms) experienced by the respondents.
Seismic Performance Analysis of Meru (Bali Pagoda): Preliminary Study
Authors: Sarassantika I. Putu Ellsa , Sulistiana Putu Didik , Sanjaya I. Gede Dhana Putra , Hartawan I. Made Nova , Tejadinata I. Gusti Ngurah Agung Eka Arya , Suwandi Kadek Yonas Prameira
Published: November 2023

This study evaluates the earthquake-resistant performance of Meru, specifically level eleven, located in the Ulun Danu Batur Kintamani Temple Area, Bali Province. Despite the upper layer’s construction with wooden frames and panels, and the base layer’s masonry walls, Meru has remained remarkably undamaged by earthquakes since its establishment in 1968. The analysis encompasses Meru’s architectural forms, structural systems, building materials, and dynamic response to seismic activity. A 3D finite element model and nonlinear time history dynamic analysis methods were employed to investigate its earthquake resistance. The findings indicate that Meru can withstand credible maximum seismicity for a return period of 2500 years, and the natural period and modes of Meru have been determined. This study serves as an initial investigation into predicting and monitoring the behavior of Meru structures during earthquakes. Future research could involve experimental analysis of individual components and the overall structure to further validate the analytical model. As a result, this study offers significant insights into the upkeep and preservation of traditional Balinese historic buildings in an earthquake-prone area.
Characteristics of Plastic Block Wall Materials (PBWM) Using Waste Engine Oil, Crackle Plastic, Mineral Water Plastic Cups Cover and Label of Plastic Bottle Without and With Rice Husk Ash and Natural Aggregates Filling Materials
Authors: Thanaya I. Nyoman Arya , Purbanto I. Gusti Raka , Putra Dewa Gede Darma
Published: November 2023

The increase of waste in Indonesia has reached 38 million tons per year and about 30% of this waste are plastic. One of the efforts is to overcome this issue is by using thin plastic waste from packaging which is rarely recycled to become plastic blocks wall material (PBWM), where the plastic was melted in hot waste engine oil (WEO). The main purpose of this study was to analyze the characteristics of the PBWM. Variation of material proportion was based on trials. The plastic waste was initially shredded to sizes about 5-10mm. On sample productions, the WEO was heated to 200°C then the shredded plastic gradually added and evenly mixed, and poured into a metal mould. The mixture was cooled down to ideal temperature for compaction of 110°C to 125°C, then left to reach room temperature. It was obtained that the Initial Rate of Suction (IRS) test results range from 0.0982-0.1012 kg/ 2.
The Quantitative Comparison of Grid Re-analysis Rainfall Products, Satellite Rainfall Products, and Hourly Rainfall Gauge Observation over Bali Province
Authors: Aryastana Putu , Wahyuni Putu Ika , Dewi Listya , Punay Jason Pajimola , Haditama I. Gusti Ngurah Hesa Respati , Jalakam Surya Pramod
Published: November 2023

Grid re-analysis and satellite-based rainfall products offers a means of estimating rainfall information at both regional and worldwide level. Numerous rainfall estimates are accessible, each varying in terms of the retrieval algorithm, sensor instrumentation, spatial-temporal resolution, and geographical coverage. The objective of this research was to assess the accuracy of grid re-analysis precipitation dataset (ERA-5) and the satellite-derived rainfall dataset (IMERG) when compared to hourly rain gauge observations in Bali Province during the period spanning 2017 to 2020. To assess grid-based datasets, conventional point-to-pixel comparison methods, along with statistical metrics in the forms of continuous, categorical, and volumetric measurements. The comparative findings illustrate that IMERG exhibits superior performance at sub-daily scales in accurately detecting volume, whereas ERA-5 demonstrates greater capability in identifying rainfall events. Both products display a tendency to overestimate the capture of low to moderate rainfall occurrences and for underestimating intense to exceptionally heavy rainfall occurrences. The IMERG product excels across various elevations.
Utilization of Rainwater Puddles at Campus I State University of Malang
Authors: Rahman Muhammad Abdul , Sulistyorini Anie , Rahayuningsih Titi , Setyawan Eko , Dewi Vita Ayu Kusuma , Dewi Mega Septia Sarda
Published: November 2023

Heavy rain that occurs on the State University of Malang campus often results in puddles. With the large water catchment area in the campus area and the many locations where rainwater pools, it is necessary to research how much rainwater can be collected. The methodology used includes collecting rain data, observing inundation locations, calculating rain using the ranking method, rational method debit calculations, water balance calculations, and storage size calculations. From the survey results, the locations that can be used as reservoirs consist of 14 locations. The area of the catchment area that has the potential to drain water into the reservoir is 69,845.10 m2. The storage capacity calculation results obtained: G1 = 178.50 m3, G1 = 80 m3, G3 = 75 m3, G4 = 108 m3, G5 = 97.5 m3, G6 = 93.6 m3, G7 = 84 m3, G8 = 22.5 m3, G9 = 67.2 m3, G10 = 83.2 m3, G11 = 41.6 m3, G12 = 36.4 m3, G13 = 65 m3, G14 = 65 m3. The amount of standing water that can be accommodated in the storage pond is 852.72 m3. The amount of standing water that can potentially be stored for 1 year is 19,553.98 m3.
An Analysis of The Use of Insulation Systems on OTTV Values of Residential Building in Hot Humid Climate
Authors: Haripram Adi Susetyo , Dewi Cynthia Permata
Published: November 2023

In tropical climates, the main problems are high solar radiation and humidity. The aim of this study is to find the right insulation material to provide thermal comfort of BSPS houses in Pamekasan Regency. The method use in this study is experimental with quantitative data analysis. Experiments were conducted on aspects that affect the value of thermal transmittance (U-value) and type of materials (glass wool, VIPs, and aerogel). The result shows that the best insulation material for thermal comfort is Vacuum Insulation Panels (VIPs). It could provide a significant reduction in OTTV value. The final results of the research by applying the insulation system to the BSPS house of Pamekasan Regency, Proppo Subdistrict, Panaguan Village show that the OTTV value of the alternative model in a house type 24 m2 is 29.505-23.462 W/m2 with a decrease of 22.86%-38.66% while in a house type 33.12 m2 it is 30.205-24.217 W/m2 with a decrease of 22.74% -38.06% and in a house type 84.46 m2 it is 27.223-21.084 W/m2 with a decrease of 26.19%-42.84%. Furthermore, the best type and thickness of insulation material used in this study is Vacuum Insulation Panels (VIPs).
Analysis of Flood Hydrograph Metro Sub Watershed with Synthetic Unit Hydrograph Snyder and SCS (Soil Conservation Service) Methods
Authors: Dewi Mega Septia Sarda , Rahman Muh. Aimar Al Qadri , Sholikhah Nafi’atus , Setyawan Eko , Sugiyanto Sugiyanto , Pranoto Pranoto , Rudianto Rudianto
Published: November 2023

Metro Sub-watershed is in Malang City. Based on data from BPBD Malang City, flood disasters have continued to increase from 2016 - 2022. The purpose of this research is to analyse the synthetic unit hydrograph (SUH) which will be used as the basis for planning water resources management. The rainfall data used in 2012-2021 with an average maximum rainfall height of 108 mm... Metro sub-watershed with an area of 31.371 km2 and a river length of 42 km and land use data with 59% of the residential. All data will be analysed for SUH in return periods Q2 = 2th, Q5 = 5th, Q10 = 10th, Q25 = 25th, Q50 = 50th, and Q100 = 100th. SUH analysis using HEC-HMS auxiliary program with Snyder and SCS (Soil Conservation Service) methods. The peak discharge results of the SUH in the Snyder method are Q2 = 47.8 m3/s, Q5 = 48.6 m3/s, Q10 = 50.7 m3/s, Q25 = 52.8 m3/s, Q50 = 54.1 m3/s, Q100 = 55.2 m3/s, and in the SCS method are Q2 = 37.5 m3/s, Q5 = 37.9 m3/s, Q10 = 39.8 m3/s, Q25 = 41.8 m3/s, Q50 = 43 m3/s, Q100 = 44 m3/s.
Morphological Evaluation of the Blended Microalgae-Activated Carbon (Mass Ratio 10:7) for Considering Its Impact on Thermal Conversion Processes
Authors: Sukarni Sukarni , Ardjaka Aufariq Citryan , Aminullah Ahmad Yusril , Zakaria Yahya , Permanasari Avita Ayu , Puspitasari Poppy
Published: November 2023

Morphology, including size, shape, and structure, plays a crucial role in determining heat and mass transfer within materials during thermal conversion processes. This study presents a concise overview of research conducted on the morphological evaluation of a blended composite consisting of microalgae and activated carbon, with a mass ratio of 10:7. To ensure homogeneity, the mixture was stirred simultaneously at 1200 rpm for 30 minutes. The blended microalgae-activated carbon composite was analyzed using scanning electron microscopy (SEM) to examine its surface structure and morphology. The SEM images revealed the presence of predominantly flake-shaped particles in the sample. The particle size distribution, determined from the SEM images, indicated that particles of approximately 30 μm in size were the most dominant. Considering the impact of this blended composite on thermal conversion processes, the findings suggest that the combination of both materials significantly enhances reactivity during thermal conversion.
Proposition for analysis of elastic deformation in ceramic tiles using multilevel factorial design
Authors: das Dores Silva Fernando , Margarido Ana Paula , de Souza Bonfim Juliana Luiza , Sordan Juliano Endrigo , Oprime Pedro Carlos
Published: November 2023

The production of ceramic tiles requires specific technical properties to allow a wide application, including covering floors and walls, building furniture, and decorative items. Current methods of measuring the dimensions of large ceramic tiles seem inadequate for products that exhibit elastic deformation due to their weight affecting the accuracy and precision of measurements. This paper aims to analyze the influence of format, thickness, and typology variables on the elastic deformation of ceramic tiles. Additionally, this study provides an analysis about which products can be measured by the traditional measurement system without compromising the quality of the results. Tests to determine warpage under different support conditions were performed using a laser-equipped coordinate measuring machine. This technology provided typology, thickness and size, and elastic deformation outcomes. In addition, a multilevel factorial design was carried out using analysis of variance (ANOVA) to investigate the influence of the selected variables. The results suggest that all the studied variables affect the elastic deformation due to the weight of ceramic tiles. The effect of interactions between predictor variables is significant mainly for the largest tiles sizes. The results also show that the current measurement method is indicated for tiles smaller than 30 × 30 cm. Further studies will be conducted to develop a new compatible and reliable method to determine the dimensional characteristics of larger ceramic tiles.
Gezielte medikamentöse Therapie der pulmonalarteriellen Hypertonie bei Patient*innen ohne Komorbiditäten
Authors: Klose Hans , Harbaum Lars , Richter Manuel J. , Lichtblau Mona , Marra Alberto M. , Kabitz Hans-Joachim , Harutyunova Satenik , Milger-Kneidinger Katrin , Lange Tobias J.
Published: November 2023

Die neuen Leitlinien der European Society of Cardiology (ESC) und European Respiratory Society (ERS) von 2022 zur pulmonalen Hypertonie fassen die aktuelle Evidenz zusammen und legen Therapiestrategien dar. Um der veränderten klinischen Präsentation der Patient*innen, bei denen eine pulmonalarterielle Hypertonie (PAH) in Europa diagnostiziert und behandelt wird, Rechnung zu tragen, werden Behandlungsempfehlungen für Patient*innen mit und ohne kardiopulmonale Komorbiditäten unterschieden. Dieser Artikel stellt die gezielte Therapie der PAH bei Patient*innen ohne kardiopulmonale Komorbiditäten vor und konzentriert sich auf Patient*innen mit idiopathischer, hereditärer, medikamenten-/toxinassoziierter oder mit Bindegewebserkrankungen-assoziierter PAH. Bei diesen Patient*innen orientiert sich die Therapieeinleitung und Anpassung im Krankheitsverlauf an einer multiparametrischen Bewertung des Mortalitätsrisikos. Für Patient*innen mit niedrigem oder intermediärem Risiko wird eine initiale, orale Kombinationstherapie (Phosphodiesterase-5-Inhibitor und Endothelin-Rezeptor-Antagonist) empfohlen. Bei Patient*innen mit hohem Risiko sollte eine Dreifach-Kombinationstherapie mit einem i. v./s. c. Prostazyklin-Analogon in Betracht gezogen werden. Wenn unter der Therapie ein niedriger Risikostatus nicht erreicht wird, sollte eine sequentielle Therapieerweiterung mit einem Prostazyklin-Rezeptor-Agonisten oder einem Prostazyklin-Analogon in Betracht gezogen werden. Alternativ kann eine Umstellung des Phosphodiesterase-5-Inhibitors auf einen Guanylatzyklase-Stimulator erwogen werden.
Medikamentöse Therapie der pulmonalarteriellen Hypertonie mit Komorbiditäten – Welche Phänotypen gibt es, was gibt es zu beachten?
Authors: Grünig Ekkehard , Halank Michael , Neurohr Claus , Behr Jürgen , Milger-Kneidinger Katrin , Ronczka Julia , Lichtblau Mona , Benjamin Nicola , Lange Tobias J. , Ulrich Silvia , Wilkens Heinrike , Grohé Christian , Skowasch Dirk
Published: November 2023

Im letzten Jahrzehnt hat sich aufgrund zunehmenden Alters bei Erstdiagnose eine Veränderung des klinischen Phänotyps mit einem vermehrten Vorkommen von Komorbiditäten bei der pulmonalarteriellen Hypertonie herausgebildet. Durch Clusteranalysen von Registerdaten wurden insbesondere ein kardialer, kardiopulmonaler und klassischer Phänotyp identifiziert.

Daten aus Subgruppenanalysen randomisierter, kontrollierter Studien und Registerdaten konnten bereits darauf hinweisen, dass auch bei Patient*innen mit pulmonalarterieller Hypertonie und kardialen Komorbiditäten, v. a. vom Linksherzphänotyp, ein Kombinationstherapieversuch unter engmaschiger Kontrolle des Therapieerfolgs und der unerwünschten Wirkungen erwogen werden kann. Das 4-Strata-Modell kann für das Monitoring und die Risikostratifizierung verwendet werden.

Die individuelle Therapieentscheidung sollte im Zentrum für pulmonale Hypertonie getroffen werden. Dabei sollten Faktoren wie Hämodynamik, Alter, Phänotyp, Anzahl und Schwere der Komorbiditäten, Therapieansprechen, Nebenwirkungen und Patient*innenwunsch berücksichtigt werden. Prospektive, randomisierte Studien zur Einschätzung der Wirksamkeit und des Nebenwirkungsprofils bei pulmonalarterieller Hypertonie mit Komorbiditäten wären wünschenswert.

Patient*innen mit einem überwiegend pulmonalen Phänotyp (Rauchen, DLCO < 45 % und/oder Lungengerüstveränderungen im CT) sprechen nach den bestehenden Daten möglicherweise weniger gut auf orale Medikamente an.
Allgemeine Maßnahmen und Management der pulmonalarteriellen Hypertonie
Authors: Lichtblau Mona , Harutyunova Satenik , Nechwatal Robert , Mayer Laura , Kabitz Hans-Joachim , Wilkens Finn Moritz , Uiker Sören , Grünig Ekkehard , Ritter Daniel , Florea Andreea , Benjamin Nicola
Published: November 2023

Die Betreuung von Patienten mit pulmonalarterieller Hypertonie (PAH) erfordert ein multimodales Konzept und Management vielschichtiger Maßnahmen, die die medikamentöse Therapie für das Management von Nebenwirkungen und der Rechtsherzinsuffizienz umfassen sowie die Aufklärung u. a. über Schwangerschaft und Flugreisen, psychosoziale Unterstützung, körperliches Training und Prophylaxe durch Impfungen.

Positive Studienergebnisse haben zu einer gesteigerten Empfehlung eines spezifischen Trainings bei pulmonaler Hypertonie geführt. Auch wurde die Empfehlung zur Eisengabe auf die aktuelle Evidenzlage angepasst.

Besonderen Fokus hat in den aktuellen Leitlinien die Ausarbeitung der Empfehlungen zu Schwangerschaftsaufklärung und Verhütung sowie dem Management einer Schwangerschaft erhalten.

In diesem Artikel soll ein Überblick über die Empfehlungen zu allgemeinen Maßnahmen und zum Management der PAH gemäß ESC/ERS-Leitlinien gegeben werden. Ergänzungen der Leitlinienempfehlungen wurden durch die Autoren als Kommentare gekennzeichnet.
Diabetes mellitus und kardiovaskuläre Prävention
Authors: Kellerer Monika , Qiu Hui Jing
Published: November 2023

Menschen mit Diabetes leiden überproportional häufig an Herzkreislauferkrankungen. Hierzu tragen auch komplexe metabolische Veränderungen und vermehrte Freisetzung von inflammatorischen Zytokinen aus dem Fettgewebe bei. Nicht zuletzt aufgrund der Herzkreislauferkrankungen liegt ein mindestens zweifach erhöhtes Risiko für einen frühzeitigen Tod im Vergleich zu Menschen ohne Diabetes vor, und die Lebenserwartung ist im Durchschnitt um etwa 5–6 Jahre kürzer. Zur Prognoseverbesserung von Menschen mit Diabetes ist eine Reduzierung der kardiovaskulären Risikofaktoren unabdingbar.
Modeling magnetically targeted drug delivery
Authors: Shapiro Maura
Published: November 2023

Fitting magnetic material to treatment enables localized and controlled drug delivery by applying a magnetic field.
Identifying emitters in fluorescent microscopy
Authors: Shapiro Maura
Published: November 2023

Discerning precisely how many fluorophores emit provides a more vivid picture of atomic behavior.
Invasion-Block and S-MARVEL: A high-content screening and image analysis platform identifies ATM kinase as a modulator of melanoma invasion and metastasis
Authors: Guo Dajiang , Jurek Russell , Beaumont Kimberley A. , Sharp Danae S. , Tan Sioh-Yang , Mariana Anna , Failes Timothy W. , Grootveld Abigail K. , Bhattacharyya Nayan D. , Phan Tri Giang , Arndt Greg M. , Jain Rohit , Weninger Wolfgang , Tikoo Shweta
Published: November 2023

Robust high-throughput assays are crucial for the effective functioning of a drug discovery pipeline. Herein, we report the development of Invasion-Block, an automated high-content screening platform for measuring invadopodia-mediated matrix degradation as a readout for the invasive capacity of cancer cells. Combined with Smoothen-Mask and Reveal, a custom-designed, automated image analysis pipeline, this platform allowed us to evaluate melanoma cell invasion capacity posttreatment with two libraries of compounds comprising 3840 U.S. Food and Drug Administration (FDA)-approved drugs with well-characterized safety and bioavailability profiles in humans as well as a kinase inhibitor library comprising 210 biologically active compounds. We found that Abl/Src, PKC, PI3K, and Ataxia-telangiectasia mutated (ATM) kinase inhibitors significantly reduced melanoma cell invadopodia formation and cell invasion. Abrogation of ATM expression in melanoma cells via CRISPR-mediated gene knockout reduced 3D invasion in vitro as well as spontaneous lymph node metastasis in vivo. Together, this study established a rapid screening assay coupled with a customized image-analysis pipeline for the identification of antimetastatic drugs. Our study implicates that ATM may serve as a potent therapeutic target for the treatment of melanoma cell spread in patients.
When Reading Gets Ruff: Welfare Challenges and Strategies in an Elementary School Dog-Assisted Literacy Program
Authors: Kirnan Jean , Thompson Ashley
Published: November 2023

The co-authors of this case report have worked collaboratively for over 10 years in a dog-assisted literacy program at an elementary school. In their roles as a teacher and a dog handler, the authors are able to provide unique insights into the challenges and strategies of successfully implementing a school-wide program. This case report addresses animal and participant welfare considerations in the specific areas of recruiting and selecting dog-handler teams, preparing teachers and students, program adaptations for differing abilities, and navigating loss due to separation or retirement. While the examples and anecdotes are from elementary children in a reading program, readers interested in animal-assisted interventions (AAIs) in other settings and with different clients can also benefit as the discussion is broad and the topics relevant to many interventions. Readers are encouraged to exercise proper preparation and planning, as well as consider the various challenges discussed, as a way to facilitate the implementation of future AAIs.

Information

© The Authors 2023
Bird Watching Tourism in Sustainable and Accessible Destinations: The Case of the Entrepreneurial Venture Explora Caloccita in the Mexican Pacific Coast
Authors: Ramos Kenia , Pérez Luis Rubén , Bassols Narcís
Published: November 2023

Bird watching is an activity that may prompt sustainable tourism development in remote communities. This case study lays out some lessons learned from the entrepreneurship case Explora Caloccita, a young venture offering bird watching to tourists in the Mexican Pacific coast. This case is based on descriptive research, laying out the practitioners’ insights and analysing the supply of experiences related to bird watching. The innovative vision of the entrepreneurs, the financial and logistical backing by the local hotel La Quinta, and the support of residents and local tour operators allow for the conclusion that bird-watching tourism has been, in this particular case, a sustainable economic alternative. Furthermore, the entrepreneurship Explora Caloccita is embedded in a destination that strongly supports accessible tourism, sustainable local development and nature preservation. The venture and the place’s sustainability are both possible thanks to the strong connections among all stakeholders and residents in the area, as locals also support the bird-watching routes and thus contribute to the conservation of the native and migrant bird species.

Information

© The Authors 2023
Integration of FDM and self-healing technology: evaluation of crack sealing by durability and mechanical strength
Authors: Hameed Noor A , Othman Farhad M , Abdul-Hamead Alaa A
Published: November 2023

The tensile zone of concrete is prone to cracking due to its limited ability to withstand tension. To address this issue, steel reinforcement is used in these specific regions. The occurrence of little cracks might potentially facilitate the ingress of liquids and gases into the reinforcing material, hence inducing corrosion. Self-healing concrete can repair and seal minuscule cracks, thus impeding the formation of corrosion. This study investigates the potential application of fused deposition modeling (FDM) for generating novel vascular networks and tubes using polylactic acid (PLA) as the material. Poly (lactic acid) (PLA) was fabricated using three-dimensional (3D) printing techniques, and its properties were compared to those of one-dimensional (1D) and two-dimensional (2D) networks. The external diameter measured 5.6 mm, while the internal diameter measured 4 mm. utilized a 10 ml volume to apply healing agents, specifically organic polyethylene glycol liquid and nano-powder (fly ash) derived from recycled materials, to all vascular structures (1D, 2D, and 3D). This application was carried out using a planetary ball mill. Following this, the prepared tubes were incorporated into a concrete beam to introduce self-healing capabilities. The water-to-cement ratio (W/C) utilized for all concrete mixtures was 0.6%, while the definite mixture proportions were 1:2.16:2.98. The quantification of the self-healing phenomenon was conducted by evaluating the restoration of load-carrying capacity following the application of a repaired specimen to a four-point bending test. Furthermore, these enhancements resulted in improved durability, increased compressive strength, and enhanced other physical characteristics. The pipes that are manufactured can be utilized to produce innovative concrete that possesses the ability to undergo self-healing processes by combining low-viscosity healing solutions (PEG) with powders (nano fly ash) that are appropriate for this application by injection into the vascular network , making it well-suited for various self-healing applications.
Sexually Transmitted Dermatophytes Can Cause Severe Infection Among Men who Have Sex With Men as Tinea Genitalis
Authors: Chromy David , Osmers Anthea-Margaux , Bauer Wolfgang Michael , Touzeau-Roemer Veronique , Borst Carina , Esser Stefan , Weninger Wolfgang , Willinger Birgit , Grabmeier-Pfistershammer Katharina
Published: November 2023

Very limited data on tinea genitalis, a potentially severe dermatophytosis transmitted during sexual intercourse affecting the genital area, suggest its potential to cause outbreaks. Thus, we investigated genital dermatophyte infections at an HIV/sexually transmitted infection clinic and identified 17 men who have sex with men (all people with HIV or pre-exposure prophylaxis users) diagnosed with tinea genitalis.
The soft X-ray background with Suzaku. II. Supervirial temperature bubbles?
Authors: Sugiyama Hayato , Ueda Masaki , Fukushima Kotaro , Kobayashi Shogo B , Yamasaki Noriko Y , Sato Kosuke , Matsushita Kyoko
Published: November 2023

Observations of the hot X-ray emitting interstellar medium in the Milky Way are important for studying the stellar feedback and for understanding the formation and evolution of galaxies. We present measurements of the soft X-ray background emission for 130 Suzaku observations at 75° < l < 285° and |b| > 15°. With the standard soft X-ray background model consisting of the local hot bubble and of the Milky Way halo, residual structures remain at 0.7–1 keV in the spectra of some regions. Adding a collisional-ionization-equilibrium component with a temperature of ∼0.8 keV, much higher than the virial temperature of the Milky Way, significantly reduces the derived C-statistic for 56 out of 130 observations. The emission measure of the 0.8 keV component varies by more than an order of magnitude: assuming the solar abundance, the median value is $3 \times 10^{-4}\, \rm {cm^{-6}\ pc}$ and the 16th–84th percentile range is $(1\!-\!8) \times 10^{-4}\, \rm {cm^{-6}\ pc}$. Regions toward the Orion–Eridanus superbubble, having a large cavity extending from the Ori OB1 association, have the highest emission measures of the 0.8 keV component. While the scatter is large, the emission measures tend to be higher toward lower galactic latitudes. We discuss possible biases caused by the solar wind charge exchange, stars, and background groups. The 0.8 keV component is probably heated by supernovae in the Milky Way disk, possibly related to Galactic fountains.
Effects of Early Aquatic Experience on Motor and Physiological Outcomes in Infants and Children Under 36 Months: A Systematic Review and Meta-analysis
Authors: Yen Hannah , Allen Diane D. , Anderson David I.
Published: November 2023

Background and Purpose:

Early aquatic experiences may benefit infants and young children with and without developmental delays, but research is limited. Our purpose was to review aquatic experience effects on motor skill, heart rate, and weight gain for participants younger than 3 years of age.

Methods:

PubMed, Science Direct, and CINAHL were searched from inception through February 2022. Included studies examined infants and children younger than 36 months having aquatic experiences, compared with not having or prior to aquatic experiences, and reported outcomes that included motor skills, heart rate, or infant weight gain. Studies were assessed for quality and potential bias using the PEDro or STROBE checklists. Effect sizes were calculated as the standardized mean difference (Cohen's d; 95% confidence interval) within and between groups in individual studies and combined across studies using random-effects models.

Results:

Twelve of 16 articles met the criteria, with 110 participants in studies assessing motor skills, 58 participants in studies assessing heart rate, and 421 newborns in studies assessing infant weight gain. Significant within-group effects were found in motor skills (d = 1.16; 0.09, 2.23), heart rate (d = −0.93; −1.54, −0.31), and weight gain (d = 1.01; 0.09, 1.92). Between-group effects were not significant in motor skills (d = 0.48; −0.49, 1.44), but were significant in newborn weight gain (d = 0.63; 0.43, 0.83). No articles reported between-group data for heart rate.

Discussion and Conclusions:

Moderately strong evidence supports the beneficial effects aquatic experiences have in infants and young children. Limitations include heterogeneity across aquatic experience protocols and measures, retrospective study design for one study, and lack of recommendations for optimal timing and duration for protocols. Additional research is needed to determine effectiveness in subpopulations at developmental risk.
Development of a Nomogram for Predicting the Risk of Hospital-Acquired Pressure Injuries in Patients in the Cardiovascular Intensive Care Unit
Authors: Li Hao-yue , Zhang Yan , Shui Xiao-lan , Che Zhi-gang , Liu Qi-fan , Guo Shan-shan
Published: November 2023

Purpose

Hospital-acquired pressure injuries (HAPIs) increase the medical burden of patients in the cardiovascular intensive care unit (CCU). Thus, identification of CCU patients with a risk for HAPIs is important. To establish a nomogram model for predicting the occurrence of HAPIs in patients in the CCU.

Methods

This was a retrospective cohort study in patients in the CCU at our hospital who developed HAPIs between January 2023 and June 2023. Patient data were extracted from the hospital’s information management system. Risk factors for HAPIs were identified using univariate and multivariate logistic regression analyses and the screened indicators were integrated into a nomogram. The effectiveness of the nomogram was evaluated and verified using receiver operating characteristic curve and decision curve analysis (DCA).

Results

In this study, a total of 161 patients were enrolled. Univariate logistic regression analysis showed that vasopressor use (OR=2.51, 95%CI=1.24–5.09,p=.010) and NT-proBNP (OR=2.92, 95%CI=1.45–5.92,p=.003), lactic acid (OR=9.43, 95%CI=4.15–21.41,p<.000), procalcitonin (OR=1.37, 95%CI=1.07–1.75,p=.012), D-dimer (OR=1.16, 95%CI=1.05–1.28,p= .004), and albumin (OR=0.88, 95%CI=0.81–0.95,p=.002) levels were independent risk factors for HAPIs. Multivariate logistic regression analysis showed that vasopressor use (OR=3.05, 95%CI=1.20–7.73,p=.019) and lactic acid (OR=12.05, 95%Cl=4.13–35.21,p<.000), procalcitonin (OR=1.30, 95%Cl=1.01–1.69,p=.043) and albumin (OR=0.82, 95%Cl=0.73–0.93,p=.002) levels were independent risk factors for HAPIs. The nomogram was well-calibrated and showed good discriminative ability (AUC=.87). The DCA showed a better net benefit, and the results were confirmed within the validation cohort.

Conclusion

The nomogram model developed in this study showed good predictability and can identify patients at risk of developing HAPIs and aid the formulation of targeted interventions.
Developing incentive mechanisms for long-term and short-term technological innovation in major engineering projects using principal-agent theory
Authors: Zhu Jianbo , Chen Jialong , Jin Wenliang , Li Qiming
Published: November 2023

Purpose

Promoting technological innovation is important to address the complexity of major engineering challenges. Technological innovations include short-term innovations at the project level and long-term innovations that can enhance competitive advantages. The purpose of this study is to develop an incentive mechanism for the public sector that considers short-term and long-term efforts from the private sector, aiming to promote technological innovation in major engineering projects.

Design/methodology/approach

This study constructs an incentive model considering the differences in short-term and long-term innovation efforts from the private sector. This model emphasizes the spillover effect of long-term efforts on current projects and the cost synergy effect between short-term and long-term efforts. It also explores the factors influencing the optimal incentive strategies for the public sector and innovation strategies for the private sector.

Findings

The results indicate that increasing the output coefficient of short-term and long-term efforts and reducing the cost coefficient not only enhance the innovation efforts of the private sector but also prompt the public sector to increase the incentive coefficient. The spillover effect of long-term innovation efforts and the synergy effect of the two efforts are positively related to the incentive coefficient for the public sector.

Originality/value

This research addresses the existing gap in understanding how the public sector should devise incentive mechanisms for technological innovation when contractors acting as the private sector are responsible for construction within a public-private partnership (PPP) model. In constructing the incentive mechanism model, this study incorporates the private sector's short-term efforts at the project level and their long-term efforts for sustained corporate development, thus adding considerable practical significance.
Let the facts speak, not the pictures: an experimental survey on rape narratives
Authors: Focacci Chiara Natalie , Lam Pak Hung
Published: November 2023

Purpose

According to statistics by the US National Sexual Violence Resource Center, more than 50% of women claim they have been raped by an intimate partner or an acquaintance. In this experiment, the authors test whether exposing individuals to different types of images portraying the victim and their perpetrator influences individuals' perception of (1) the perpetrator's deserved punishment and (2) the role played by the victim in her rape.

Design/methodology/approach

In an experimental survey, the authors randomly treat groups of individuals with manipulated facial and physical expressions of the same photographs.

Findings

The authors find that news about rape are more or less effective in uncovering the seriousness of the crime independent of the pictures accompanying them, suggesting media should avoid their misusage.

Originality/value

While the role of the narrative of rape has been extensively discussed in the literature from a theoretical perspective, this research provides original evidence based on actual behavioural response.
A conceptual framework for a new service model: digital servitization with an Industrial 4.0 perspective
Authors: Adsiz Tilbe , Ozturkoglu Yucel
Published: November 2023

Purpose

Recently, increasing costs and competitive pressure have accelerated the search for different business models in both the production and service sectors. The rapid development of technology has increased the importance of digitalization, especially in developing new and different strategies. The digital service business model has also become a new business model that companies have recently preferred. In addition to its many advantages, it is a business model in which different barriers arise in practice. When we look at the literature, there are very few studies, especially on digital servitization. The purpose of this study is to integrate the concept of digital servitization with the Industry 4.0 perspective.

Design/methodology/approach

To achieve this aim, first, the authors identify various challenges and barriers in front of digital servitization based on the Industry 4.0 perspective. Later, they determine the relative importance of these barriers critical to the success of digital servitization. Lastly, one multi-criteria decision-making method, the fuzzy decision-making trial and evaluation laboratory method, is used to analyze the cause-and-effect relationship between each barrier based on the Industry 4.0 perspective

Findings

Based on the results, the most crucial cause-and-effect barriers are insufficient infrastructure/lack of IT infrastructure and high implementation, respectively. Therefore, this study offers the reader the possible barriers to sustainable digital servitization with Industry 4.0 perspective implementations and comprehensive solutions for these barriers. In addition, this study draws a roadmap for disseminating digital service applications.

Originality/value

There is no study, to the best of the authors’ knowledge, about determining barriers and problems with merging digital servitization with the Industry 4.0 perspective. So, there is still a significant gap in the literature about investigating these two essential topics from the Industry 4.0 perspective.
Anti‐inflammatory and antioxidative actions of tacrolimus (FK506) on human microglial HMC3 cell line
Authors: Kocanci Fatma Gonca , Goksu Azize Yasemin
Published: November 2023

Microglial cells are indispensable for the normal development and functioning of neurons in the central nervous system, where they play a crucial role in maintaining brain homeostasis by surveilling the microenvironment for signs of injury or stress and responding accordingly. However, in neurodegenerative diseases, the density and phenotypes of microglial cells undergo changes, leading to chronic activation and inflammation. Shifting the focus from neurons to microglia in drug discovery for neurodegenerative diseases has become an important therapeutic target. This study was aimed to investigate the potential of Tacrolimus (FK506) an FDA‐approved calcineurin inhibitor, to modulate the pathology of neurodegenerative diseases through anti‐inflammatory and antioxidative effects on microglial activation. The human microglia clone 3 (HMC3) cells were exposed to 1 μg/mL LPS in the presence and absence of doses of FK506. Survival rates of cells were determined using the 3‐(4,5‐Dimethylthiazol‐2‐yl)‐2,5‐Diphenyltetrazolium Bromide (MTT) method. Morphological evaluation of cells showed that FK506 restored the normal morphology of activated microglia. Furthermore, FK506 treatment increases the total antioxidant capacity and reduces the total oxidative capacity, indicating its potential antioxidant effects. Data from ELISA and RT‐PCR analyses showed that LPS abolished its promoting effects on the release of proinflammatory IL‐1β and IL‐6 cytokines in HMC3 cells, reflecting the anti‐inflammatory effect of FK506. These findings support the idea that FK506 could be a promising therapeutic agent for neurodegenerative diseases by modulating microglial activation and reducing inflammation and oxidative stress.
Historical associations and spatiotemporal changes of pathogen presence in ticks in Canada: A systematic review
Authors: Crandall Kirsten E. , Millien Virginie , Kerr Jeremy T.
Published: November 2023

Background

Starting in the early 20th century, ticks and their pathogens have been detected during surveillance efforts in Canada. Since then, the geographic spread of tick vectors and tick‐borne pathogens has steadily increased in Canada with the establishment of tick and host populations. Sentinel surveillance in Canada primarily focuses on Ixodes scapularis, which is the main vector of Borrelia burgdorferi, the bacterium causing Lyme disease. Other tick‐borne pathogens, such as Anaplasma, Babesia, and Rickettsia species, have lower prevalence in Canada, but they are emerging or re‐emerging in tick and host populations.

Aims/Materials & Methods

Here, we assessed the historical associations between tick vectors, hosts and pathogens and identified spatiotemporal clusters of pathogen presence in ticks in Canada using data extracted from the literature.

Results

Approximately one‐third of ticks were infected with a pathogen, and these ticks were feeding primarily on bird and mammal hosts. B. burgdorferi was the most detected pathogen and I. scapularis harboured the greatest number of pathogens. We identified several spatial outliers of high pathogen presence in ticks in addition to five spatiotemporal clusters in southern Canada, all of which have long‐established tick populations. Six spatiotemporal clusters of high pathogen presence in ticks were also identified based on surveillance method, with four clusters associated with passive surveillance and two clusters associated with active surveillance.

Discussion

Our review represents the first systematic assessment of the literature that identifies historical associations and spatiotemporal changes in tick‐host‐pathogen disease systems in Canada over broad spatial and temporal scales.

Conclusion

As distinct spatiotemporal clusters were identified based on surveillance method, it is imperative that surveillance efforts employ standardized methods and data reporting to comprehensively assess the presence, spread and risk of tick‐borne pathogens in tick and host populations.
Interfacial reactivity in the Co/CuO samples as investigated by x-ray photoelectron spectroscopy
Authors: Chourasia A. R. , Chopra D. R.
Published: November 2023

The interfacial reactivity at the Co/CuO interfaces has been investigated in situ by the technique of x-ray photoelectron spectroscopy. Thin films of cobalt were evaporated on the CuO substrates by the technique of e-beam. The depositions were undertaken by maintaining the substrates at ambient temperature. Significant differences have been observed in the Cu 2p core level spectra recorded for these samples and that for pure CuO. The Co 2p core level spectrum also shows differences upon comparison with the spectrum for elemental cobalt. These differences arise from chemical interaction occurring at the Co/CuO interface. The curve fitting technique has been utilized to estimate the relative percentages of the constituents at the interface. The interface width has been determined from the relative percentage of the unoxidized cobalt present in the overlayer. The dependence of the interface width has also been explored as a function of annealing temperature. The interface width is much less for the room temperature deposited sample as compared to that for annealed samples. The spectral data also indicate increase in the diffusion of copper oxide through the cobalt overlayer with increasing temperature.