bluuebunny/crossref_metadata_2025 huggingface dataset:
P-092 INJURY MANAGEMENT PRACTICE IN AUSTRALIA AS AN OCCUPATIONAL PHYSICIAN
Authors: Shahzad Farhan
Published: July 2024

Introduction

The proposed session is to discuss injury management consultation in Australia as legislation incorporated into the Workers’ Compensation system.

Methods

We will discuss the effect on Workers’ Compensation return-to-work timeframes and management outcomes. Discussion about the history and the progress of the Workers’ Compensation System in Australia. Discuss injury management consultation with Australian statistics. Comparative analysis of New South Sales and other states in Australia including Victoria, Australian Capital Territory, Queensland, Northern Territory, Western Australia and Tasmania.

Results

Outcomes of legislative support with occupational injury management promote the scope of work for occupational physicians. NSW has increased the scope of practice and employability for occupational medicine practitioners as authorized providers of occupational medical services with rehabilitation and return to work in workers’ compensation claims.

Discussion

The role of occupational physicians in Workers’ Compensation return to work is crucial.

Conclusion

Legislative inclusion of Occupational Medicine practitioners should be promoted in workers’ compensation government schemes.
O-061 INVESTIGATING WORK-RELATED FACTORS AND INFECTION RISK DURING THE COVID PANDEMIC: POOLED ANALYSIS OF DATA FROM THE UK LONGITUDINAL LINKAGE COLLABORATION (UK-LLC)
Authors: Gittins Matthew , Carder Mel , Seed Martin , Iskandar Ireny , Daniels Sarah , Van Tongeren Martie , Gittins Matthew , Rhodes Sarah , Wels Jacques , Wielgoszewska Bozena , Zhu Jingmin , Shaw G. Richard J , Hamilton Olivia K L , Demou Evangelia , Stevenson Anna , Badrick Ellena , Rhead Rebecca , Katikireddi Vittal , Ploubidis George B , Van Tongeren Martie
Published: July 2024

Introduction

We investigated how work-related factors such as key worker status, furlough, and working from home were associated with infection risk during the COVID-19 pandemic. We also explored how these relationships differed given the definition of an infection i.e. self-reported infection vs diagnostic test.

Methods

The UK LLC has collated data from 15 UK national cohort studies initiated since the 1960s and linked to NHS testing data. Each cohort surveyed participants at multiple stages during the pandemic, asking questions relating to several characteristics including self-reported infection status and occupational factors. We pooled risk ratios across cohort specific mixed effects Poisson regression models to investigate the association between work-related characteristics and infection due to both the self-reported infection status and the linked diagnostic test-positive infection status.

Results

Of the 15 studies, approximately 72,290 individuals responded 136,453 times to COVID surveys between March 2020 and March 2021. During which 10.8% (20% individuals) self-reported an infection whereas 1.9% (4.1% individuals) were linked to a positive test result. Pooled risk ratios indicated for self-reported infection that ‘key workers’ and ‘not-home working’ were at 23% and 7% increased risk whereas furlough, and ‘part-time workers’ both decreased risk by 7%. Linked positive infection was consistently associated with a greater magnitude in the effect with a 70% (compared to 23%) increased risk for keyworkers.

Discussion and conclusion

These results give a better understanding of the influence of work-related characteristics had on infection risk. Careful consideration of the infection definition also appears to be an important consideration when interpreting the influence of these characteristics.
O-062 A MORE ACCURATE PREVALENCE OF PTSD AND COMMON MENTAL DISORDERS IN HEALTHCARE WORKERS IN ENGLAND: A TWO-PHASE EPIDEMIOLOGICAL SURVEY
Authors: Stevelink Sharon , Lamb Danielle , Greenberg Neil , Wessely Simon , Madan Ira
Published: July 2024

Introduction

Previous studies on impact of the COVID-19 pandemic on healthcare workers’ (HCWs) mental health relied on self-reported screening measures to estimate point prevalence. Screening measures, designed to be sensitive, have low positive predictive value and often overestimate prevalence. We present a more accurate prevalence of common mental disorders (CMDs) and post-traumatic stress disorder (PTSD) among HCWs in England using diagnostic interviews.

Methods

A two-stage, cross-sectional study comprising diagnostic interviews (n=337) within a larger multi-site longitudinal cohort of HCWs (n=23,462) was conducted during the COVID-19 pandemic. This included two representative participant groups: i) 243 participants completed the General Health Questionnaire (GHQ-12) and the Clinical Interview Schedule – Revised (CIS-R) to assess CMDs; ii) 94 participants completed the PCL-6 and the Clinician Administered PTSD Scale (CAPS-5) for DSM-5 – to assess PTSD.

Results

The GHQ screening caseness for any CMD was 52·8% (95% CI 51.7 to 53.8). Using the CIS-R diagnostic interviews, the estimated population prevalence of generalised anxiety disorder was 14.3% (95% CI 10.4 to 19.2) and for depression 13.7% (95% CI 10.1 to 18.3). The PCL-6 screening caseness for PTSD was 25·4% (95% CI 24.3 to 26.5). Using the CAPS-5 diagnostic interviews, estimated population prevalence of PTSD was estimated at 7·9% (95% CI: 4.0 to 15.1).

Discussion

Implications for clinical practice, policy and future research will be discussed.

Conclusion

Prevalence estimates of CMDs in HCWs are considerably lower when estimated using diagnostic interviews than through screening tools. Nevertheless, 1-in-7 HCWs met the threshold for a clinically diagnosable mental disorder who might benefit from intervention.
O-064 COMMON CANCERS EXCESSES AMONG EMERGENCY SERVICE WORKERS
Authors: Demers Paul , Berriault Colin , Dakouo Mamadou , Kirkham Tracy , DeBono Nathan , Sritharan Jeavana
Published: July 2024

Introduction

Much attention has been focused on identifying cancer risks among firefighters and little on other emergency service workers. We investigated cancer risks among paramedics in Ontario, Canada, and compared their results to patterns observed among firefighters and police.

Methods

This study used the Occupational Disease Surveillance System; 2.37 million former worker’s compensation claimants linked to the Ontario Cancer Registry. Cox proportional hazard models were used to calculate sex and age-adjusted hazard ratios (HRs) and 95% confidence intervals (CIs). Results for firefighters and police were previously published, this is the first presentation of paramedic results.

Results

We identified 7,355 paramedics (Ncancers=289); and previously identified 13,642 firefighters (Ncancers=1,730), and 22,595 police (Ncancers=2,377). Compared to workers in all other occupational groups in the cohort, various excesses unique to these three groups were observed, but there were some striking similarities. For all three, we observed similar excesses of malignant melanoma (HRPara=2.03, CI=1.37-3.01; HRFF=2.38, CI=1.99-2.84; HRPol=2.27, CI=1.96-2.62) and prostate cancer (HRPara=1.44, CI=1.13-1.83; HRFF=1.43, CI=1.31-1.57; HRPol=1.47, CI=1.35-1.59) while decreased risks of lung cancer were observed in all three groups.

Discussion

Similarities between firefighters and police have been previously observed, but this is the first study to investigate cancer risks in paramedics. The assumption has generally been that cancer excesses in firefighters were due to their unique exposure. However, emergency service workers share some common carcinogenic exposures, including high-stress, vehicle exhaust, intermittent solar radiation, and night shift work.

Conclusion

Exploring similarities/differences between paramedics and other emergency responders may improve understanding of cancer etiology and inform primary prevention and screening efforts.
O-072 TRAJECTORIES OF MUSCULOSKELETAL PAIN FROM MIDLIFE TO OLD AGE: A MULTICOHORT, LONGITUDINAL STUDY
Authors: Neupane Subas , K.C Prakash , Kyrönlahti Saila , Nygård Clas-Håkan
Published: July 2024

Introduction

This study aimed to study the developmental patterns of musculoskeletal pain from working life to old age. We also studied the associations of lifestyle factors with trajectories of musculoskeletal pain.

Methods

Data from four independent cohort studies from Finland (FLAME), the UK (ELSA), Norway (MUST), and the USA (HRS) were used. Analysis was based on the participants who were employed or those looking for jobs at baseline. Musculoskeletal pain was defined as pain in one or more body parts of the musculoskeletal system (yes/no). Latent class growth modeling (LCGM) was applied to identify trajectories of the number of pain sites. The association of the trajectories of musculoskeletal pain with baseline lifestyle factors was studied using multinomial logistic regression models.

Results

Three class trajectories of musculoskeletal were found from midlife to old age in all cohorts. Overall, 12% of people were in the high trajectory group in ELSA, 14% in MUST, 19% in HRS, and 23% in FLAME.

Discussion

The pooled estimate shows that smoking was associated with a high trajectory of musculoskeletal pain (OR 1.44, 95% CI 1.12-1.75), while physical activity and alcohol intake had no significant association with high musculoskeletal pain.

Conclusion

A substantial proportion of people have more than one site of pain consistently from working life to old age. Lifestyle-related factors play an important role in the development of MSP. Lifestyle interventions may reduce the impact of MSP which should be started already at working age when major non-communicable diseases and permanent disability are still very rare.
O-077 EXPOSOME CHARACTERIZATION OF DIESEL ENGINE EXHAUST EXPOSURE
Authors: Lan Qing , Vermeulen Roel , Rahman Mohammad , Dai Yufei , Hu Wei , Irving Brooklynn McNeil , Lin Xiangping , Blechter Batel , Chaoyang Dianzhi Ren , Duan Huawei , Wong Jason , Niu Yong , Xu Jun , Chaoyang Wei Fu , Meliefste Kees , Hosgood Dean , Ye Meng , Jia Xiaowei , Meng Tao , Bin Ping , Silverman Debra , Zheng Yuxin , Rothman Nathaniel , Walker Douglas
Published: July 2024

Introduction

Exposure to diesel engine exhaust (DEE) is associated with increased lung cancer risk; however, underlying molecular mechanisms remain unclear. We apply an exposome approach to characterize early biological effects of occupational DEE exposure.

Methods

Plasma samples from 54 diesel engine factory workers and 55 non-exposed control workers were characterized using an integrated exposome platform that combines untargeted gas chromatography (GC-) and liquid chromatography (LC-) with high-resolution mass spectrometry (HRMS). Exposome profiles were evaluated by metabolome-wide association study (MWAS) for molecular features associated with DEE exposure and elemental carbon. Potential molecular mechanisms underlying DEE were further evaluated by integrating exposome profiles with plasma proteomics, urine aminopyrenes and mutagenicity, and buccal gene expression analysis.

Results

GC- and LC-HRMS untargeted analysis detected 68,285 metabolic features. Comparison of DEE-exposed and non-exposed workers identified 772 molecular features associated with exposure at a FDR <5%, including 102 detected using GC-HRMS and 670 detected using LC-HRMS. Molecular networking and annotation identified compounds consistent with DEE exposure, while metabolic pathway enrichment suggest alterations in oxidative stress and endothelial pathways. We conducted a secondary MWAS to link urinary mutagenicity, reflecting systemic exposure to genotoxic/carcinogenic agents, and associated with tumor development and identified 90 molecular features positively associated with urine mutagenicity at FDR<5%.

Discussion

Integration of exposome profiles with protein and genome-wide gene expression identified biological alterations consistent with many of the key characteristics of carcinogens.

Conclusion

Integrated exposome characterization of DEE exposure identified novel DEE biomarkers and biological response profiles in a high exposure setting.
O-079 DO HUMIDIFIER DISINFECTANTS CAUSE LUNG CANCER?: STANDARDIZED INCIDENCE RATIO OF LUNG CANCER IN THE HUMIDIFIER DISINFECTANT VICTIM COHORT
Authors: Ahn Yeon Soon , Park Soyoung , Lee Jongin
Published: July 2024

Introduction

Humidifier Disinfectants(HDs) contained various chemicals, including polyhexamethylene guanidine (PHMG) and oligo(2-(2-ethoxy)ethoxyethyl guanidinium (PGH)), as ingredients. While several respiratory diseases have been recognized as health damages caused by HDs, there is currently no known association with lung cancer. However, a recent PHMG exposure study conducted on rats resulted in lung cancer, and when human alveolar epithelial cells were treated with PHMG, carcinogenesis-related genetic changes were observed. Consequently, there is a need for an epidemiological study on humans.

Methods

The objective of this study was to assess the risk of lung cancer among HD victims. The HD victim cohort was comprised of 7,343 registered claimants. Exposure histories were merged with the Korea National Health Insurance Service(KNHIS) data to assess cancer morbidity between 2002 and 2020. Standardized incidence ratios (SIRs) with reference to Korean were analyzed.

Results

The number of lung cancer cases was 109 in men and 86 in women. The SIRs of lung cancer were 2.77 (N=64, 95% CI=2.13–3.54) in men and 9.18 (N=53, 95% CI=6.87–12.00) in women with a 5-year lag.

Discussion and conclusion

The cohort used in this study consists of claimants who reported health damage caused by HD exposure, which causes a significant selection bias compared to a cohort of individuals solely exposed to HDs. However the majority of claimed diseases were respiratory issues, only a small proportion of confirmed lung cancer cases claimed caused by HDs. Therefore the findings of this study provide valuable insights into the potential association between HDs and the development of lung cancer.
O-080 OCCUPATIONAL EXPOSURE TO CARCINOGENS AMONG MIGRANT WORKERS IN THE UNITED ARAB EMIRATES
Authors: Adam Balazs , Elbarazi Iffat , El-Zaemey Sonia , Sharjah Basema Saddik , Sadig Mohamed El , Abdullahi Aminu S , Fritschi Lin , Sheek-Hussein Mohamud
Published: July 2024

Introduction

Occupational carcinogens may be induced by physical, chemical, biological and organizational workplace hazards. In the United Arab Emirates (UAE), migrant workers account for 80% of labor. Being sometimes employed as unskilled workers and more willing to work in demanding jobs, their vulnerability to harmful exposures may be increased. This study aimed to estimate the prevalence of occupational exposure to carcinogens among migrant workers in the UAE.

Methods

A sample of employees working in construction, cleaning, dry cleaning, mechanic workshops and hair salons were recruited and interviewed. Using OccIDEAS (an online assessment tool), participants were asked questions about their demographics, work history and regular tasks. Exposure to various carcinogens was estimated using the in-built algorithms of OccIDEAS.

Results and discussion

A sample of 1778 workers was included. The sample consisted of workers from Bangladesh (19.2%), India (31%), Nepal (4.7%), Pakistan (29.9%) and the Philippines (4.8%), with the rest from other nationalities. Overall, the prevalence of probable exposure was considerable, with the highest among drivers (96%) and the lowest among laundry workers (52%). Moderate to high exposure was found to 20 different carcinogens. Self-rated health among those who were exposed to carcinogens was significantly lower than among those not exposed (AOR = 0.783, 95% CI [0.638–0.961]).

Conclusion

Exposure to several different carcinogens is relatively common in the UAE among migrant workers. Further policy development and implementation of tailored interventions are needed to prevent exposure to occupational carcinogens and, consequently, to combat occupational cancer in the UAE.
O-081 EPIDEMIOLOGICAL TRENDS OF AGE-STANDARDIZED RATES FOR WORKPLACE ACCIDENTS IN JAPAN (2012–2019)
Authors: Zaitsu Masayoshi , Tsushima Saki , Hirohashi Sora , Niki Shinji
Published: July 2024

Introduction

The aging workforce in Japan poses a growing concern regarding its potential impact on workplace accidents. Nevertheless, there is a lack of epidemiological studies analyzing statistical trends in workplace accidents at the national level.

Methods

We conducted a trend analysis using publicly available national data spanning 2012 to 2019 in Japan. Using age-stratified annual data and statistics from the Reports of Occupational Accidents and Diseases, sourced from the Ministry of Health, Labour, and Welfare, we examined occupational fatalities and workplace accidents requiring a leave of four or more days. Age-standardized rates (ASRs) were calculated using the direct method with 10-year age categories. Temporal trends were assessed with Joinpoint regression analysis.

Results

Occupational fatalities exhibited a significant ASR decline, with an annual percent change (APC) of 5.1% (95% CI 6.8–3.3). However, no significant changes in ASR for overall workplace accidents were observed. Furthermore, when categorized by industry, the healthcare sector demonstrated an increasing ASR trend, with an APC of 2.2% (95% CI 1.1–3.3).

Discussion and conclusion

This study is the first to report the epidemiological trend in workplace accidents in Japan. The findings indicate a positive outcome in the reduction of occupational fatalities in Japan, possibly attributable to improved safety measures and awareness. However, the stability in overall workplace accident rates suggests a need for targeted interventions to mitigate accident risks in the aging workforce, especially in industries with increasing trends, such as healthcare.
O-082 ASSOCIATIONS BETWEEN JOB CONTROL AND ISCHEMIC HEART DISEASE MORTALITY AMONG SWEDISH MEN
Authors: Almroth Melody , Hemmingsson Tomas , Falkstedt Daniel , Kjellberg Katarina
Published: July 2024

Introduction

Previous studies of low job control and IHD mortality have shown mixed results. The aim of this study is to investigate the association between job control and IHD mortality among Swedish men in their mid-50s followed up prospectively while accounting for potential confounding throughout the life-course.

Methods

The study is based on a register-linked cohort of 46,565 men who conscripted for the Swedish military in 1969/1970. Job control was measured using a job-exposure matrix (JEM) linked to the men’s registered occupations in 2005 and categorized into quintiles. They were followed regarding IHD deaths between 2006 and 2020. Cox regression models were used to estimate crude and adjusted hazard ratios. Models were adjusted for childhood socioeconomic position, factors from conscription at age 18 (divorced parents, psychiatric and musculoskeletal diagnoses, emotional control, cognitive ability, body mass index, blood pressure, alcohol consumption, and smoking), highest attained education, and occupational physical workload.

Results

Compared to the highest job control category, those with lower job control had an increased risk of IHD mortality in the crude model (HR 1.40, 95% CI 1.07-1.83 for medium high; HR 1.52, 95% CI 1.17-1.97 for medium; HR 2.13, 95% CI 1.66-2.73 for medium-low; and HR 2.92, CI 95% 2.31-3.69 for low). No significant associations remained in the adjusted model.“

Discussion

This study contributes to previous research through the possibility to adjust for several important explanatory factors. The results are limited to older Swedish men.

Conclusion

Associations between low job control and IHD mortality appear to be non-causal and explained by other life-course factors.
O-084 AUTOIMMUNE MANIFESTATIONS OF OCCUPATIONAL SILICA EXPOSURE IN THE STONE BENCHTOP INDUSTRY, VICTORIA, AUSTRALIA
Authors: SM Gwini , RF Hoy , K Walker-Bone
Published: July 2024

Introduction

Artificial stone typically contains extremely high concentration of crystalline silica (90%). The Stone Benchtop Industry (SBI) in Australia started using artificial stone in the early 2000s but unfortunately practices in the sector including dry-cutting, polishing and inadequate ventilation and respirator use has exposed workers in this industry to a very high risk of silicosis. Silica exposure has also been associated with a range of other clinical complications including systemic autoimmune diseases such as systemic sclerosis, SLE (Lupus), rheumatoid arthritis and Sjogren’s syndrome. Therefore, we investigated the prevalence of a diagnosis of a systemic autoimmune condition and of biomarkers of autoimmune disease including: anti-nuclear antibodies (ANAs); rheumatoid factor (RF) and extractable nuclear antigens (ENAs) in this group of SBI workers.

Methods

From 2019, workers in the SBI in Victoria were offered free health screening for silica-associated conditions. Workers participated in a protocolised program coordinated by an occupational health provider, under the supervision of an occupational physician. The assessment included systematic collection of information about symptoms including joint pains, dry eyes/mouth, Raynaud’s and skin conditions, and blood was taken for assessment of erythrocyte sedimentation rate (ESR), ANAs, ENAs and RF.

Results

Blood-test results from 469 workers were analysed (n=453 males, mean age 41 years and n=175 with a final diagnosis of silicosis). Five workers had received a diagnosis of an autoimmune condition. RF>14 IU/mL was found in 8.5% and 3.7% of workers with and without silicosis, respectively (p=0.062). ANA was detected in 103 workers (n=52/137, 38.0% silicosis cases and n=51/236, 21.6% without silicosis, p=0.001) and was present in titres usually regarded as clinically significant in 54 workers. ENA was positive in 9.8% (with no significant differences between diagnosis groups).

Discussion and conclusion

In this young, predominantly male cohort of SBI workers, considerably increased rates of detectable ANAs, ENAs and RF indicate that silica exposure has triggered autoimmune activation. Whilst few workers were identified to have manifested clinical autoimmune disease currently, there is potential for a high rate of incident disease in future and longitudinal follow-up is required.
P-100 OCCUPATIONAL EXPOSURE AND CO-EXPOSURE TO PHYSICAL CONSTRAINTS AND NEUROTOXIC CHEMICALS IN FRENCH WORKERS: RESULTS FROM THE SUMER STUDY
Authors: Bodin Julie , Babin Jessica , Bertin Mélanie , Roquelaure Yves
Published: July 2024

Introduction

Given the high incidence of carpal tunnel syndrome in the working population and the co-exposure of workers, it is necessary to improve knowledge of the joint effects of physical and chemical exposures in order to improve prevention strategies. The aim of this study was to assess the prevalence of occupational exposure and co-exposure to physical constraints and neurotoxic chemicals.

Methods

The study sample was composed of 26,444 workers included in the French cross-sectional survey SUMER 2017s. Occupational exposure within the previous week of work were assessed using a questionnaire during face-to-face interviews with occupational physicians. Four physical constraints were studied: manual handling of loads, forceful joints exertion, repetitive movement and hand-arm transmitted vibrations. Nineteen neurotoxic chemicals were studied: perchloroethylene, trichloroethylene, white-spirit, formaldehyde, etc. Analyses were conducted using weighted data.

Results

Approximately 24% of men and 11% of women were exposed to at least one physical constraint, and 14% of men and 12% of women were exposed to at least one neurotoxic chemical. About 6% of men and 3% of women were co-exposed to physical constraints and neurotoxic chemicals. Male and female workers under 30 years old and blue-collar workers were more co-exposed than other workers. Male workers in the construction were more co-exposed than other male workers.

Discussion

Despite the frequency of co-exposures, very few data are available in the literature on the combined effects of physical and neurotoxic chemical exposures on the risk of CTS.

Conclusion

Occupational co-exposure to physical constraints and neurotoxic chemicals was observed in a significant proportion of French workers.
P-104 MORBIDITIES AMONG ALCOHOL BREWERY WORKERS IN INDIA
Authors: Mhalshekar Sweta , Mhalshekar Vishwaraj
Published: July 2024

Introduction

The alcohol brewery industry produces alcoholic beverages, and it has become a global industry. Brewery workers may be exposed to occupational hazard such as noise and exposure to chemicals. They might also be susceptible to alcohol-related health issues. The study aimed to assess specific morbidities among alcohol brewery workers in India and recommend measures to minimize hazards.

Methods

A retrospective record-based cross-sectional study was conducted over a period of 3 months. The data of 115 workers was obtained and was analyzed using SPSS version 23. Chi-square test was used to find association between qualitative variables.

Results

The records of 115 workers were analyzed, out of which 91.3% were male and 8.69% were females. It was observed that 31.3% were overweight with a BMI of > 25, 13% workers were hypertensive, 0.8% had abnormal ECG findings, 5.2% were diabetic, 13.9% had far vision deficit, 24.3% had near vision and 1.7% had anemia. 6.9% of the workers had abnormal audiometry tests. Liver function tests were deranged in 7.2% of the workers.

Discussion

The workers of alcohol brewery suffer from several occupational health problems such as hearing impairments and abnormal liver functions as well as lifestyle diseases like diabetes, hypertension and obesity.

Conclusion

This study stresses the need for regular health surveillance of workers in an alcohol brewery to detect any deviations from heath along with information, instruction and training on use of appropriate PPE. Lifestyle modifications such as exercise and healthy diet should be inculcated amongst the workers to prevent non communicable diseases.
P-106 OCCUPATIONAL CLASS AND RISK OF PARKINSON’S DISEASE: A CASE-CONTROL STUDY-BASED DATA FROM A NATIONWIDE HOSPITAL GROUP IN JAPAN
Authors: Nakazawa Shoko , Fukai Kota , Furuya Yuko , Hoshi Keika , Kojimahara Noriko , Toyota Akihiro , Tatemichi Masayuki
Published: July 2024

Introduction

This study investigates the association of occupational class with Parkinson’s disease (PD).

Methods

This was a nationwide, multicenter, hospital-based matched case-control study included patients with PD (ICD–10, G20) and controls without mental/ behavioral disorders or nervous system diseases (ICD–10, F, G), aged ≥ 20 years who were initially hospitalized between 2005 and 2020. 10 controls matched by age, sex, admission year and hospital were selected for each case. Participants were grouped into the 12 longest-held occupational class by the Japanese Standard Occupational Classification and Japanese Standard Industrial Classification. We conducted conditional logistic regressions to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for risks of PD adjusted for alcohol consumption and smoking status.

Results

There were 2,077 cases and 20,368 controls. Service workers in service industry were set as reference. Professionals in service industry and white-collar industry showed higher risk of PD (ORs=2.35 (1.48–3.73) and 1.35 (1.15–1.59)). Stratified with smoking status, professionals in service industry remained an increased risk of PD in current smokers. Current and former smokers had lower risks of PD (0.36 (0.30–0.43) and 0.73 (0.66–0.80)). Furthermore, researchers (2.97 (1.06–8.28)), doctors/ dentists/veterinarians/ pharmacists (1.84 (1.17–2.87)), religious workers (2.31 (1.09–4.91)), musicians and stage designers (4.55 (1.39–14.8)) showed higher risk of PD.

Discussion

Although smoking had an inhibitory effect on PD, there were risk in specific professionals. It is significant to clarify the occupational factors that increase risk of PD.

Conclusion

Occupational class was possibly associated with PD risk.
P-110 TRENDS IN THE PREVALENCE RATE RATIO OF CHRONIC DISEASES AT A SEMICONDUCTOR COMPANY COMPARED TO THE NATIONAL PREVALNCE RATE
Authors: Na Wonwoong , Hong Dongui , Lee Jiae , Kwon Hyukhwa , Cho Jaehyun , Kim Gawon , Heo Jieun
Published: July 2024

Introduction

The SK hynix Employee Cohort (SHE cohort) was launched in 2017 to identify the causes of occupational diseases in the semiconductor industry and to conduct various research activities to promote the health of its members. The SHE cohort is a dynamic cohort with 25,505 participants as of December 2022.

Methods

In order to prevent occupational diseases in the semiconductor industry and improve the health of employees, SK hynix organized the Committee for Advanced and Sustainable Occupational Health in 2017 and analyzes the prevalence of chronic diseases annually. As a control group for comparison, data from the Korea National Health and Nutrition Examination Survey from 2017 to 2021 were standardized by age and gender to obtain the prevalence rate ratio (PRR), which was analyzed using the empirical quantile method for five-year trends.

Results

The average PRR for hypertension over the five-year period was 0.49, with an annual percent change(APC) value of -2.44. The mean PRR and APC for diabetes prevalence was 0.78 and 2.30 respectively and the mean PRR and APC for dislipidemia prevalence was 0.66 and 5.53 respectively. The mean PRR for obesity was 0.97 with an APC of -0.49, and the mean PRR for metabolic syndrome was 0.72 with an APC of -1.17.

Discussion and conclusion

There were no statistically significant trends. For all chronic diseases, a low PRR can be interpreted as a health worker effect. Obesity had a relatively high PRR, which should be considered when prioritizing the allocation of healthcare resources in the workplace.
P-111 HEAVY METALS BLOOD LEVEL ASSESSMENT AMONG WORKERS LIVING IN HEAVY METALS EXPOSED AREA IN JAVA ISLAND, INDONESIA
Authors: Fitriani Dewi Yunia , Prodia Mulyana Mulyana , Istiani Nur , Tebet Ari Prayogo , Bose-O’Reilly Stephan , Mansyur Muchtaruddin
Published: July 2024

Introduction

Lead polluted areas, attributed to the activities of collecting and recycling of used lead acid batteries, are widespread throughout Indonesia, including on Java Island. This presentation is an initial analysis of the study which is aimed to determine the blood levels of various heavy metals among workers residing in heavy metals polluted areas of Java, Indonesia.

Methods

The initial analysis of this cross-sectional study included a total of seventy male workers who reside in lead-exposed areas but work in a variety of industrial settings. Five milliliters of whole blood was drawn and stored using EDTA tube. The metal levels were measured by Inductively coupled plasma mass spectrometry (ICP-MS). The socio-demographic characteristics of the respondents were gathered using questionnaires. The Research Ethics Committee of Faculty of Medicine at Universitas Indonesia has approved the study in March 2023.

Results & discussion

There were 23,9% of respondents, aged between 20 and 62 years old, working directly exposed to heavy metals, as welders, smelting labor, and battery seller. Results showed that blood Lead, cadmium and chromium levels were significantly higher in the respondents working exposed to heavy metals with P<0,001, P=0,02, and P=0,03 consecutively. There was no significant difference for other metals such as Mangan, Arsenic, and Cobalt. No significant age-based differences were found in terms of all metals.

Conclusion

The occupational exposure remains a significant contributor to elevated heavy metal blood levels, regardless of their living area. This also showed the importance of workplace intervention to control the exposures.
P-116 RELATIONSHIP BETWEEN DAILY SLEEP DURATION AND METABOLIC SYNDROME-RELATED ITEMS IN POLICE OFFICERS
Authors: Nogawa Kazuhiro , Sakuma Sayaka , Watanabe Yuuka , Suwazono Yasushi
Published: July 2024

Introduction

Many police officers tend to have irregular lifestyles due to shift work, investigative activities, etc., and many of them do not get enough sleep. We examined the relationship between sleep duration and findings of metabolic syndrome-related items in annual health examinations among police officers.

Methods

The participants were 9,633 men and 1,086 women who underwent the legally-required annual health screenings in a Prefectural Police. Based on this self-administered questionnaire, we obtained information on daily sleep duration. Fisher’s exact test was performed on the prevalence of obesity, hypertension, lipids, blood sugar, and metabolic syndrome, respectively, based on the results of the medical examinations.

Results

Short sleep duration (≤5 hours) was significantly related to obesity, hypertension, metabolic syndrome, and blood glucose in men. In women, only lipid was significant.

Discussion

In police officers, a comparison of sleep duration and prevalence of metabolic syndrome-related items revealed significant associations in a number of items. The importance of ensuring adequate sleep hours for maintaining good health was demonstrated.

Conclusion

It needs to promote various health measures such as lifestyle disease countermeasures and promotion of work-life balance, not merely longer or shorter work hours, but more importantly, whether or not sleep is being obtained.
P-117 ASSESSING EXHALED BREATH CONDENSATE AS MINIMALLY INVASIVE MATRIX FOR LUNG-RELATED BIOMARKER ANALYSES
Authors: De Ryck Evi , Verscheure Eline , Schlünssen Vivi , Stierum Rob H , Pronk Anjoeka , Godderis Lode , Ghosh Manosij
Published: July 2024

Introduction

Inhalation is an important route wherethrough occupational exposure can reach and potentially affect pulmonary function. Recently, there is a shift towards using less invasive matrices. We investigated quality and stability of exhaled breath condensate (EBC) as a minimally invasive matrix to identify lung-related biomarkers.

Methods

EBC and lung function measurements were collected, from twelve healthy participants twice six months apart (T1,T2) using Medivac® TurboDECCS System and spirometry. Cytokines, MMP-1, 2, 7, and 9, VEGF/Flt1, E- and P-selectin, α-amylase activity, proteomics, CysLTs, LTB4, and TXB2 were measured in EBC. This study was approved by the Ethics Committee Research UZ/KU Leuven (S64599).

Results

Only two out of twenty-four EBC samples exhibited detectable α-amylase activity. Proteomics showed presence of proteins involved in several biological processes, originating from different cellular components, with different molecular functions. Negative associations were shown between forced expiratory flow (FEF) 25% and TXB2(T2), and FEF 75% and forced expiratory volume within the first second (FEV1) and IFNγ(T1). Peak expiratory flow positively associated with CysLTs(T1) and IL6(T2), FEF 25% with CysLTs(T1), FEF 75% with IL8(T1), FEV1 with IL2 and IL6(T2), and forced vital capacity with IL1β, IL2, and IL6(T2).

Discussion

With only limited saliva contamination, the collection procedure for EBC is robust. Several associations were shown between spirometry parameters and various markers, suggesting the potential of EBC as alternative minimally invasive matrix.

Conclusion

So far, these results support the usage of EBC to identify biomarkers for lung function. EPHOR is funded by the European Union’s Horizon 2020 research and innovation programme under grant agreement number 874703.
P-121 POSITIVE OUTCOME EXPECTANCIES AND PERCEIVED RESILIENCE AS POTENTIAL SOURCES OF WITHIN-GROUP HETEROGENEITY IN THE REPORTING OF EXHAUSTION SYMPTOMS AMONG SWEDISH SCHOOL PRINCIPALS
Authors: Persson Roger , Leo Ulf , Håkansson Carita , Oudin Anna , Arvidsson Inger , Österberg Kai , Leo Ulf , Håkansson Carita , Oudin Anna , Arvidsson Inger
Published: July 2024

Introduction

Beliefs and expectations are psychological mechanisms of relevance for stress and health, yet they are often overlooked as a source of within-group heterogeneity when it comes to reporting epidemiological survey data. Accordingly, we examined to what extent positive outcome expectancies (POE) and perceived resilience change the reporting of exhaustion symptoms.

Methods

Cross-sectional data from 2219 Swedish school principals (78% women; mean age 49 years [SD 7 years]) were analyzed. The Karolinska Exhaustion Disorder Scale (KEDS) and the Lund University Checklist for Incipient Exhaustion (LUCIE) were used to classify exhausted versus non-exhausted principals. Low, medium, or high levels of POE and resilience were determined via generalized self-efficacy scores and two single items “Have you lately felt hopeful for the future” and “You are a stress tolerant person, that is, you quickly bounce back after difficulties in work and private life.”

Results

Most principals reported high Generalized self-efficacy (88.0%), high Hope for the future (67.6%), and high resilience (90.0%). Principals reporting low POE, or low resilience, reported more exhaustion symptoms. Adjusted logistic regression analyses showed that low Hope for the future scores were strongly associated with exhaustion in LUCIE (OR=12.3, 95% CI=8.0-19.0, p <.001) and KEDS (OR=12.6, 95% CI=8.4-18.8, p<.001).

Discussion

The associations between low hope for the future and exhaustion symptoms is a reminder that a positive outlook on life is a vital part of mental health and a potential area for psychological intervention.

Conclusion

Positive outcome expectancies and perceived resilience are potential sources of heterogeneity in the reporting of exhaustion symptoms in epidemiological surveys.
P-122 WORK-RELATED ROAD TRAFFIC ACCIDENTS: IMPACT OF THE EMERGENCE OF NEW PERSONAL MOBILITY DEVICES. ANALYSIS BASED ON DATA FROM A REGISTER OF ROAD TRAFFIC ACCIDENTS
Authors: Fort Emmanuel , Connesson Nicolas , Brière Julien , Ndiaye Amina , Gadegbeku Blandine , Charbotel Barbara
Published: July 2024

Introduction

In the last decade, in several countries, the use of personal mobility devices (PMDs) has steadily increased.

Objective

This study aimed to describe the characteristics of work-related road accidents and their evolution since the introduction of new PMDs in France, in terms of incidence and severity.

Methods

A cross-sectional study was performed using data from the Rhône Road Trauma Registry, focusing on users aged 18–70 years who were injured in work-related road accidents between 2015 and 2020.

Results

10,653 victims were identified. An increase in the number of work-related traffic injuries was observed, mainly due to an increase in the number of accidents while commuting (approximately 4%). The proportion of scooter drivers increased by more than 660%. In contrast, the share of car drivers decreased by 21% over the period, and motorized two-wheeler drivers by 24%. Most scooter users had upper limbs (59.2%), lower limbs (46.8%), face (21.2%) or head (17.9%) injuries. Most accidents were of low or moderate severity (97.9%; MAIS score < 3) compared to other users (93.4% for pedestrians, 95.5% for motorized two-wheelers, 97.5% for bicycle, p<0.0001). Less than one-fifth of injured PMD and scooter users wore helmets.

Discussion

The use of PMDs has steadily increased in France. However, accidents involving scooters or other PMDs seem to be of low severity.

Conclusion

Many head injuries could be prevented with more widespread use of helmets, among scooter- and other PMD users and bicycle users. Companies could take preventive actions to ensure that employees are better informed.
P-123 EVALUATION OF THE CAUSES OF DEATH OF PATIENTS WITH ESTABLISHED DIAGNOSIS OF ASBESTOSIS
Authors: Kovalevskiy Evgeny , Kashanskiy Sergey
Published: July 2024

Introduction

In assessing the prevalence of diseases potentially associated with asbestos exposure the mortality rates are recognized as the most reliable index. But this indicator does not allow to estimate the prevalence of asbestos-related diseases, which are often not indicated in death certificates as the main cause of death, such as asbestosis.

Methods

Initial review of the causes of death in a group of 850 chrysotile asbestos mining and enrichment workers with diagnosis “asbestosis” established in the territorial center of occupational health from 1946 to 2020 carried out using death certificates’ national electronic database.

Results

210 workers of the group died. The average age of deceased was over 60 years old. The peak age of mortality was for women 71-80 years, for men 61-70. Asbestosis was identified as the main cause of death for only 9 patients (3 men and 6 women). Most of the death causes (46.1%) were diseases of the circulatory system, malignant neoplasms (32.0%). In men, the main cancer sites were respiratory and chest organs (56.7%), digestive (20.0%), urinary tract (13.3%). Women died more often from cancer of the digestive organs (37.8 %), respiratory organs and chest (27.6%), female genital organs (13.8%) and breast (10.3%). The third ranking place was respiratory diseases (8.3%).

Discussion/Conclusion

Even initial review demonstrated that asbestosis itself in modern conditions is practically not considered as the main cause of death, which indicates the need for a wider study of the incidence of non-malignant occupational asbestos-related diseases in the country with special attention to exposure conditions, occupational history and lifestyle factors.
P-130 THE PREVALENCE OF STRESS AND BURN-OUT AMONG HEALTH CARE-PROFESIONNALS IN THE PREFECTURE OF MÉKNES CITY DURING COVID 19 PANDEMIC
Authors: Amellah Amal
Published: July 2024

Introduction

Psychiatric related diseases such as burnout and stress have recently begun to attract attention among health professionals espacialy during and in post pandemic period, our study aims to examine whether prevalence of burnout and stress are higher among community nurses and medical staff engaged in public health services of meknes city.

Methods

Our cross-sectional study involved 200 health workers in public hospitals working under stress during COVID 19 pandemic. A questionnaire was shared with participants during tow month. The degree of stress and burn out symptoms was assessed using the 14-item of perceived stress scale and the 23 items of the Maslach-burnout inventory.

Results and discussion

60% were women. A considerable proportion of participants reported higher score of percieved stress (47%) and 43% of respondants are calssed with a higher score of burn-out.

Multivariable logistic regression analysis showed that being married, and parent of children, and involved in intensive care units and in emergency services, were associated with a higher prevalence of stress and burnout. The Prevalence of burnout and stress are significantly elevated among nurses and medical stuff engaged during COVID19 pandemic

Conclusion

working in emergency services and during public health crisis appear to represent work environment factors contributing to stress and burnout.
P-132 THE PREVALENCE OF DECREASED KIDNEY FUNCTION IN MANUFACTURE WORKERS AND ITS ASSOCIATED RISK FACTORS: AN ANALYSIS OF BIG DATA FROM WEST JAVA, INDONESIA’S INDUSTRY WORKERS
Authors: Kekalih Aria , Nurhadi Ferdy , Ilyas Muhammad , Soemarko Dewi , Sugiarta Iwan
Published: July 2024

Introduction

Chronic kidney disease is a global health issue due to its increased prevalence, severe morbidity and mortality, and profound socio-economic effects. The manufacturing sector in Indonesia exposes many workers to long hours, heat, and low humidity, which may increase their risk of renal disease. Thus, early diagnosis of decreasing kidney function and related factors is essential.

Methods

A big data Analysis of 2304 manufacturing workers in West Java, Indonesia was performed using compiled 2022 medical checkup databases from twelve companies. West Java was chosen since it has the most workers in Indonesia. Gender, age, physical activity, history of urinary tract illnesses, smoking, alcohol, and current comorbidities (metabolic syndrome and urinalysis) are included. Manufacturing kinds, working hours, heat exposure, workload, prolonged seated >4 hours, and ergonomic position were occupational factor risks. Kidney function was impaired when eGFR was below 90 mL/min/1.73 m². Univariate and multivariate risk factor analyses were performed.

Results

The prevalence of decreased kidney function was 33.8% of workers. The significant factor risks were male (aOR 2.52), age over 40 years old (aOR 2,48), conditions of grade I and II hypertension (aOR 1,88 and 2.15 consecutively), obesity (aOR 1.27) and working more than 20 years (aOR 1.93).

Discussion

Higher prevalence than average global prevalences indicated kidney failure threat. Recognising that heat exposure and ergonomic position were unrelated, workers’ drinking habits and implementation of hydration programmes must be monitored.

Conclusion

Imminent kidney failure must be prevented in manufacturing workers, especially in male, older, obese, and long-term manufacturing employees with hypertension.
P-133 ASSOCIATION BETWEEN WORKPLACE VIOLENCE AND ANXIETY AMONG HEALTHCARE WORKERS DURING THE COVID-19 PANDEMIC IN BRAZIL
Authors: Feijó Fernando , Reis Elaine , Helioterio Margarete , Werneck Guilherme , Araújo Tânia
Published: July 2024

Introduction

The COVID-19 pandemic changed several aspects of the work organization and aggravated psychosocial risk factors for healthcare workers. Those changes may be more serious in a social context where there is a lack of resources and huge social inequalities. Therefore, the aim of this study was to investigate the association between workplace violence/harassment and anxiety among healthcare workers in Brazil.

Methods

Cross-sectional study with a representative sample of public health employees who worked in the primary and secondary care in three municipalities in Bahia, northeastern Brazil, in 2021. Anxiety Disorder was measured by the Patient Health Questionnaire(PHQ). Workplace violence and bullying/harassment were assessed using the self-labeled method, with validated specific questions. A structured questionnaire and other validated instruments were used to assess sociodemographic, behavioral and psychosocial factors. Logistic regression was used to estimate prevalence odds ratios and 95% confidence intervals.

Results

1097 workers participated in the study. The prevalence of bullying was 8.2%, and the prevalence of Anxiety Disorder was 18.9%. After adjustment for confounders, healthcare workers exposed to verbal/physical aggression and workplace bullying had 1.90 (95% CI: 1.23-2.95) and 2.29 (95% CI: 1.41-1.37) higher odds of anxiety, compared to those non-exposed, respectively.

Discussion

The results highlight the possible role of the work organization for the occurrence of workplace aggression, workplace bullying and anxiety.

Conclusion

Interventions to prevent mental health outcomes, particularly anxiety, as well as sick leave and work disability, must focus on the work organization and managerial policies, minimizing psychosocial risk factors and eliminating violence and harassment from the healthcare environment.