bluuebunny/crossref_metadata_2025 huggingface dataset:
Risk factors of severe dengue in children
Authors: Naaraayan Sridevi A. , Sundar Kuthanoor Chinnasamy
Published: September 2021

Background:

Dengue is a mosquito-borne viral disease whose severity varies from a mild undifferentiated fever to severe fatal form. The objectives of this study were to determine the prevalence and risk factors of severe dengue.

Subjects and Methods:

This nested case–control study was done in a medical college hospital in South India from October 2019 to January 2020. Children between 1 month and 12 years of age who presented with fever without focus and tested positive for dengue serology were included. Demographic data, anthropometry, clinical features, and laboratory parameters were noted down from all children. Severity of illness was classified according to the World Health Organization dengue guidelines 2009. Prevalence of severe dengue was expressed in proportion with 95% confidence interval (CI). Bivariate analysis was performed using Chi-square test, Fisher's test, and Student's t-test, and a P < 0.05 was considered statistically significant.

Results:

Out of 370 children, 192 (51.9%) had dengue without warning signs, 168 (45.4%) had dengue with warning signs, and 10 had severe dengue. The prevalence (95% CI) of severe dengue was 2.7% (1.3%–4.9%). Abdominal pain/tenderness (odd's ratio [OR] - 7.429), facial puffiness (OR - 4.333), hepatomegaly (OR - 3.857), and pleural effusion (OR - 13.222) were the significant risk factors for severe dengue.

Conclusions:

The significant risk factors for severe dengue were abdominal pain/tenderness, facial puffiness, hepatomegaly, and pleural effusion.
Probiotics in critically ill children
Authors: Angurana Suresh Kumar , Mehta Ankit
Published: September 2021

Gut microbiome is a complex ecosystem where good microbes outnumber pathogenic bacteria. Gut microbiome plays important role in host biology, function, physiology, and immune response by performing nutritive and immune functions and by providing physical barriers against pathogenic microorganisms. Critical illness leads to disruption of the gut microbiome, colonization with and overgrowth of pathogenic microorganisms, translocation of pathogens and their toxins, systemic inflammatory response syndrome, and sepsis. Probiotics restore gut microbiome, improve the barrier function of gastrointestinal tract, and prevent bacterial translocation. Commonly used probiotics are Lactobacillus, Bifidobacterium, and Saccharomyces. Enteral administration of probiotics has been shown to reduce the rate of necrotizing enterocolitis, candida colonization, candidiasis, sepsis, feed intolerance, mortality, and duration of hospital stay among preterm infants; and ventilator-associated pneumonia and antibiotic-associated diarrhea in critically ill children. Few studies suggested that probiotics supplementation among critically ill children resulted in reduction in the rate of candida colonization and candidiasis; and modulation of inflammation. However, there are safety concerns with probiotics as there are few reports of bacteremia/sepsis and fungemia in immunocompromised cases. Further, well-designed multicentric studies are needed to give clear answers on the dose and duration of treatment, the effectiveness of a single or multiple strain of probiotics, risk-benefit potential, and cost-effectiveness in critically ill children.
The link between abnormalities of calcium handling proteins and catecholaminergic polymorphic ventricular tachycardia
Authors: Lin Ding-Jyun , Lee Wen-Sen , Chien Yu-Chung , Chen Tsung-Yu , Yang Kun-Ta
Published: September 2021

Catecholaminergic polymorphic ventricular tachycardia (CPVT), a rare autosomal dominant or recessive disease, usually results in syncope or sudden cardiac death. Most CPVT patients do not show abnormal cardiac structure and electrocardiogram features and symptoms, usually onset during adrenergically mediated physiological conditions. CPVT tends to occur at a younger age and is not easy to be diagnosed and managed. The main cause of CPVT is associated with mishandling Ca2+ in cardiomyocytes. Intracellular Ca2+ is strictly controlled by a protein located in the sarcoplasm reticulum (SR), such as ryanodine receptor, histidine-rich Ca2+-binding protein, triadin, and junctin. Mutation in these proteins results in misfolding or malfunction of these proteins, thereby affecting their Ca2+-binding affinity, and subsequently disturbs Ca2+ homeostasis during excitation–contraction coupling (E-C coupling). Furthermore, transient disturbance of Ca2+ homeostasis increases membrane potential and causes Ca2+ store overload-induced Ca2+ release, which in turn leads to delayed after depolarization and arrhythmia. Previous studies have focused on the interaction between ryanodine receptors and protein kinase or phosphatase in the cytosol. However, recent studies showed the regulation signaling for ryanodine receptor not only from the cytosol but also within the SR. The changing of Ca2+ concentration is critical for protein interaction inside the SR which changes protein conformation to regulate the open probability of ryanodine receptors. Thus, it influences the threshold of Ca2+ released from the SR, making it easier to release Ca2+ during E-C coupling. In this review, we briefly discuss how Ca2+ handling protein variations affect the Ca2+ handling in CPVT.
О регулярном поведении целых функций нулевого порядка
по кривым правильного вращения
Authors: Zabolotskii N V , Mostova Mariana Romanivna , Shvets V E
Published: September 2021

Исследована связь между существованием $\upsilon$-плотности
$\Delta^\gamma(\alpha,\beta)$ корней по кривым правильного
вращения целой функции нулевого порядка и регулярным поведением
на бесконечности ее логарифма.
Библиография: 10 названий.
Разрешимость независимых систем уравнений
в конечно порожденных нильпотентных группах
Authors: Roman'kov Vitalii Anatol'evich
Published: September 2021

Доказывается, что проблема разрешимости
конечной независимой системы уравнений
в конечно порожденной нильпотентной группе эффективно сводится
к аналогичной проблеме в некоторой конечной фактор группе
этой группы. Следовательно, данная проблема
алгоритмически разрешима. Тем самым усиливается теорема
А. Г. Маканина о финитной аппроксимируемости и
алгоритмической разрешимости регулярного расщепимого уравнения
в конечно порожденной нильпотентной группе.
Библиография: 12 названий.
Абсолютная непрерывность спектра трехмерного периодического
магнитного оператора Шрeдингера с сингулярным электрическим потенциалом
Authors: Danilov Leonid Ivanovich
Published: September 2021

Доказана абсолютная непрерывность спектра трехмерного периодического магнитного
оператора Шрeдингера с электрическим потенциалом типа производной от меры
$V=d\mu /dx$, если обобщенная функция $d|\mu|/dx$ ограничена относительно
оператора $-\Delta$ в смысле квадратичных форм с гранью, не превосходящей
некоторой постоянной $C(A)\in (0,1)$. На периодический магнитный потенциал $A$
накладываются условия, которые, в частности, выполнены, если
$A\in H^q_{\mathrm{loc}}(\mathbb R^3;\mathbb R^3)$, $q>1$, или
$A\in C(\mathbb R^3;\mathbb R^3)\cap H^q_{\mathrm{loc}}(\mathbb R^3;\mathbb R^3)$,
$q>1/2$.
Библиография: 34 названия.
О регулярности решения уравнения Прандтля
Authors: Petrov Vladimir Ernestovich , Suslina Tatiana Aleksandrovna
Published: September 2021

Изучаются вопросы разрешимости и регулярности решения задачи Дирихле для
уравнения Прандтля
$$
\frac{u(x)}{p(x)}-\frac{1}{2\pi}\int_{-1}^1\frac{u'(t)}{t-x} dt=f(x),
$$
где $p(x)$ - положительная функция на $(-1,1)$, причем $\sup(1-x^2)/p(x)<\infty$.
В терминах специального интегрального преобразования на отрезке вводится шкала
пространств $\widetilde H^s(-1,1)$. Устанавливается теорема существования
и единственности решения в классах $\widetilde H^{s}(-1,1)$ при $0\le s\le 1$.
В частности, при $s=1$ результат таков: если $r^{1/2}f\in L_2$, то
$r^{-1/2}u,r^{1/2}u'\in L_2$, где $r(x)=1-x^2$.
Библиография: 11 названий.
Об одном тождестве Рамануджана и его обобщениях
Authors: Daniyarkhodzhaev Aleksandr Timurovich , Korolev Maxim Aleksandrovich
Published: September 2021

В настоящей заметке предложен новый способ вывода теоретико-числовых
тождеств, который применяется к доказательству многомерного аналога
одного из тождеств С. Рамануджана. Предлагаемый способ позволяет получать
новые представления в виде бесконечных рядов для числа $\pi$, значений
дзета-функции Римана и $L$-рядов Дирихле в целых точках.
Библиография: 14 названий.
Динамические эффекты, связанные с потерей устойчивости положений равновесия и периодических траекторий
Authors: Neishtadt Anatolii Iserovich , Treschev Dmitry Valerevich
Published: September 2021

Изучается динамическая система, зависящая от параметра $\kappa$. Предполагая, что система имеет семейство положений равновесия или периодических траекторий, гладко зависящих от $\kappa$, мы интересуемся деталями потери устойчивости, происходящей через различные бифуркации (Пуанкаре-Андронова-Хопфа, удвоения периода и т. д.). Рассматриваются две основные постановки задачи. В первой $\kappa$ постоянен и предметом анализа служит явление мягкой и жесткой потери устойчивости. Во второй постановке $\kappa$ медленно меняется со временем (случай динамической бифуркации). В простейшей ситуации мы имеем $\kappa=\varepsilon t$, где $\varepsilon$ - малый параметр. В более общем случае $\kappa(t)$ может быть решением медленного дифференциального уравнения. В случае динамической бифуркации анализ в основном сконцентрирован вокруг явления затягивания потери устойчивости.
Библиография: 88 названий.
Стационарные точки функции Минковского
Authors: Gayfulin Dmitry Radislavovich , Kan Igor' Davidovich
Published: September 2021

В статье доказывается новая теорема о производной функции Минковского.
Библиография: 11 названий.
О регуляризованной асимптотике решения задачи Коши при наличии слабой точки поворота у предельного оператора
Authors: Eliseev Aleksandr Georgievich
Published: September 2021

В работе построено методом регуляризации Ломова асимптотическое решение линейной задачи Коши при наличии "слабой" точки поворота у предельного оператора. Выписаны в явном виде основные сингулярности данной задачи. Приведены оценки по $\varepsilon$, характеризующие поведение сингулярностей при $\varepsilon\to 0 $. Доказана асимптотическая сходимость регуляризованных рядов. Результаты работы проиллюстрированы примером.
Библиография: 8 названий.
Асимптотика оператора рассеяния для волнового уравнения в сингулярно возмущенной области
Authors: Korikov Dmitrii Vladimirovich
Published: September 2021

Рассматривается семейство задач Коши-Дирихле для волнового уравнения в неограниченных областях $\Lambda_{\varepsilon}$ ($\varepsilon\geqslant 0$ - малый параметр); c каждой задачей связан оператор рассеяния $\mathbb{S}_{\varepsilon}$. При $\varepsilon>0$ границы областей $\Lambda_{\varepsilon}$ гладкие, в то время как граница предельной области $\Lambda_{0}$ содержит коническую точку. Выводится асимптотика оператора $\mathbb{S}_{\varepsilon}$ при $\varepsilon\to 0$.
Библиография: 11 названий.
A Study on Diesel Spray Flame by Time-Resolved PIV with Chemiluminescence of OH*
Authors: Jo Hyun , Kawai Yuta , Horibe Naoto , Hayashi Jun , Kawanabe Hiroshi , Ishiyama Takuji
Published: September 2021

To clarify the relationship between the local heat release and the velocity distribution inside the diesel spray flame, simultaneous optical diagnostics of OH* chemiluminescence and particle image velocimetry (PIV) have been applied to the diesel spray flame under the elevated in-cylinder pressure and temperature conditions formed in a rapid compression expansion machine (RCEM). The cranking speed of the RCEM was 900 rpm, and the in-cylinder pressure and temperature were 8 MPa and 800 K at the start of injection, respectively. The amount of fuel was 10.2 mg. The injection pressure was 120, 90, and 60 MPa. To minimize the disturbance of luminous flame on optical diagnostics, a solvent, with comparable combustion characteristics to diesel fuel was used as fuel. The oxygen concentration was set to 15%. Results clearly show that PIV can successfully analyze the velocity distribution in diesel spray flames. The local velocity fluctuation inside the diesel spray flame represents the peak value slightly inside of the high-temperature region. In addition, the intensity of local velocity fluctuation increases as the injection pressure increases.
«Арестный» залог в делах о банкротстве
Authors: Кукин А.В. , Плешанова О.П.
Published: September 2021

Проект изменений в Закон о банкротстве предлагает дополнить ст. 138 Закона и признать обеспеченными залогом требования лиц, в чьих интересах был наложен арест на распоряжение имуществом. Тем самым залог в силу ареста — «арестный» (или «арестантский») залог, — изначально вызывавший серьезные споры среди ученых и практиков, может быть легализован в делах о банкротстве, что позволит кредиторам, в пользу которых наложен арест, получить статус залоговых. Это не только изменит судебную практику, но и существенно усложнит институт залога, породив множество вопросов о старшинстве залогов разного вида и очередности удовлетворения требований залоговых кредиторов.
Проектируемый п. 8 ст. 138 Закона о банкротстве предусматривает, что статус залоговых кредиторов должны получить «управомоченные» лица, в чьих интересах был наложен запрет на распоряжение имуществом в соответствии с п. 2 ст. 174.1, п. 5 ст. 334 Гражданского кодекса (ГК), а также рядом положений Налогового кодекса (НК) РФ. Указанные требования «признаются обеспеченным залогом соответствующего имущества с момента наложения такого запрета». Проектируемая норма специально оговаривает, что правила о залоге в силу ареста «применяются независимо от снятия (прекращения) соответствующих запретов на распоряжение имуществом», предусмотренных для процедур наблюдения и конкурсного производства (абз. 4 п. 1 ст. 63, абз. 9 п. 1 ст. 126 Закона о банкротстве). В проектируемых п. 9–11 ст. 134 Закона о банкротстве делается попытка установить очередность удовлетворения требований различных залоговых кредиторов, в том числе с учетом возможной субординации требований. Очевидно, что предлагаемое регулирование охватывает главным образом требования налогового органа и банков, но не учитывает сложные случаи залога и наличие квазизалоговых требований, которые создают проблемы и без вмешательства «арестного» залога.
В статье будут рассмотрены следующие вопросы:
1) законодательство и судебная практика о залоге и аресте имущества;
2) основания возникновения «арестного» залога;
3) соотношение «арестного» залога с иными требованиями, обеспеченными залогом имущества, согласно Проекту;
4) проблема старшинства различных видов залога и квазизалоговых требований (удержание, кристаллизация залога и др.);
5) проблема публичности залога и возможность оспаривания залога в силу ареста.
PELATIHAN PEMBUATAN BAHAN AJAR UNTUK PEMBELAJARAN DARING MENGGUNAKAN APLIKASI VIDEO EDITING BAGI GURU DAN CALON GURU
Authors: Munawaroh Munawaroh , Parimita Widya , Parlyna Ryna , Susanti Santi , Sumiati Ati , Zulaihati Sri
Published: September 2021

The training is part of the community service activities of the lecturers of the Faculty of Economics, Universitas Negeri Jakarta. This Workshop is to educate and train teachers or prospective teachers to make teaching materials that are certainly interesting for students. Given the current COVID-19 pandemic, where everyone is encouraged to work or distance learning, all teachers must also teach students remotely. In addition, this training is also to prepare teachers to continue to adapt to the times because it is possible that learning and teaching activities will be carried out online and offline in the future.
PKM PENANAMAN NILAI KARAKTER MELALUI MASA TAARUF SISWA MADRASAH DALAM KONDISI NORMAL BARU COVID-19 DI MA PLUS NURUL ISLAM SEKARBELA
Authors: Rizaldi Dedi Riyan , Zaenudin Muhamad , Fakhrurrozi Fakhrurrozi , Fatimah Ziadatul
Published: September 2021

Research has been carried out which aims to determine the implementation of introducing the madrasa environment to prospective new students through the activities of the Ta’aruf Period of Madrasah Students. This study uses a qualitative approach with the method of observation. This research was conducted on all prospective new students of MA Plus Nurul Islam Sekarbela for the academic year 2021/2022, with a total of 45 people. The implementation of the research went through two stages, namely the delivery of material and the introduction of the madrasa environment. Based on the results of observations and discussions, it can be seen that the activities of the Madrasah Student Ta’aruf Period are essential for prospective new students to get to know more about the conditions, characteristics, and environment of the madrasa. In addition, this activity instills various character values of madrasah children through various activities that are integrated with religious contexts to meet the goals set previously
Genome assembly and annotation of the tambaqui (Colossoma macropomum): an emblematic fish of the Amazon River Basin
Authors: Hilsdorf Alexandre Wagner Silva , Uliano-Silva Marcela , Coutinho Luiz Lehmann , Montenegro Horácio , Almeida-Val Vera Maria Fonseca , Pinhal Danillo
Published: September 2021

Colossoma macropomum, known as “tambaqui”, is the largest Characiformes fish in the Amazon River Basin and a leading species in Brazilian aquaculture and fisheries. Good quality meat and excellent adaptability to culture systems are some of its remarkable farming features. To support studies into the genetics and genomics of the tambaqui, we have produced the first high-quality genome for the species. We combined Illumina and PacBio sequencing technologies to generate a reference genome, assembled with 39× coverage of long reads and polished to a consensus quality value (QV) of 36 with 130× coverage of short reads. The genome was assembled into 1269 scaffolds (a total of 1,221,847,006 bases), with a scaffold N50 size of 40 Mb, where 93% of all assembled bases were placed in the largest 54 scaffolds corresponding to the diploid karyotype of the tambaqui. Furthermore, the NCBI Annotation Pipeline annotated genes, pseudogenes, and non-coding transcripts using the RefSeq database as evidence, guaranteeing a high-quality annotation. A Genome Data Viewer for the tambaqui was produced, which will benefit groups interested in exploring the unique genomic features of the species. The availability of a highly accurate genome assembly for tambaqui provides the foundation for the discovery of novel ecological and evolutionary insights, and is a helpful resource for aquaculture.
Using real-world cases, innovation and rhetorical tools to teach social pharmacy
Authors: Nørgaard Lotte Stig , Møllebæk Mathias , Halstrøm Per Liljenberg , Riis Nina Louise Fynbo , Christensen Vibeke Brix , Arevalo Lourdes Cantarero
Published: September 2021

Background: Innovation refers to the process in which individuals or organisations transform ideas into novel products, services or processes. Pharmacy graduates are increasingly expected to have the competencies necessary to find innovative solutions to medicine-related challenges, particularly solutions addressing patient´s need and societal aspects of medicine use.
Objective: To describe and discusses the rationale, development, implementation and evaluation of the pharmacy course ‘Contemporary Social Pharmacy’ (CONSOC), and to summarise lessons learned.
Methods: Several methods and models were used to develop, run and evaluate the course. The course examination consisted of a written report and an oral presentation and defence of the report. The course was evaluated through a student assessment questionnaire and oral and written feedback from case providers and the teachers.
Results: Three selected case reports representing particularly innovative solutions are described. The student evaluations revealed that nine out of 14 course learning objectives were either fully or partly fulfilled, and that what students liked best from the course were the teamwork, the open discussions, the real-world cases and the innovation features. The teachers and case providers also found the course rewarding and extremely positive.
Conclusion: Teaching innovation opens up new possibilities for educators and researchers. The CONSOC course introduced several novel components, but the increased complexity of the course also presented challenges to students and faculty alike.
Intervención multidisciplinaria del trabajador social en el área gerontológica
Authors: Bailón Anchundia Cristhian Michael , Loor Lino Ligia Estela
Published: September 2021

La vulneración de las personas adultas mayores requiere atención especializada por organismos que aporten en su calidad de vida, como respuesta a la problemática que puede complicarse en los ámbitos sociales. El objetivo de esta investigación consistió en identificar la intervención multidisciplinaria del trabajo social en el área gerontológica en el centro Gerontológico Guillermina Loor de Moreno de la ciudad de Portoviejo, Ecuador. El estudio fue de tipo descriptivo, con un enfoque cualitativo, como fuente de recopilación de información se utilizó la técnica de la entrevista y como instrumento la guía de entrevista que se aplicó a la trabajadora social del centro gerontológico. Los resultados demuestran que la participación de la trabajadora social con el equipo multidisciplinario en el proceso de valoración de la persona adulta mayor permite realizar acciones de organización, programación y evaluación de las actividades del centro por lo que se implementan actividades complementarias como realizar la identificación, mapeo y coordinación de redes con otras instituciones, que de manera eficaz permiten a las personas adultas mayores en situación de calle incorporase al centro gerontológico. La gestión interinstitucional que realiza el trabajo social en el centro gerontológico le permite integrar estrategias de prevención y promoción de la salud buscando acciones integrales de manera paliativa, la cual sigue procesos sistemáticos de evaluación.
Potensi Antioksidan Menggunakan Metode DPPH Ekstrak Beras Hitam (Oryza Sativa L Indica) dan Penghambatan Tirosinase
Authors: Febram Prasetyo Bayu , Madyastuti Purwono Rini , Valgar Novarino Alvin
Published: September 2021

Black Rice (Oryza sativa L. Indica) adalah beras yang biasa digunakan untuk meningkatkan kesehatan. Beras hitam memiliki bentuk fisik yang mirip dengan nasi pada umumnya, namun permukaan beras ini berwarna ungu kehitaman. Penelitian ini bertujuan untuk menguji aktivitas antioksidan dan inhibitor tirosinase dalam ekstrak beras hitam. Penelitian dilaksanakan pada bulan Februari 2019 sampai Agustus 2019. Dengan menggunakan metode eksperimen. Beras hitam diekstraksi dengan metode maserasi menggunakan etanol 96% pelarut, kemudian dilakukan beberapa tes menggunakan spektrofotometri. Parameter yang diamati termasuk hasil tes fitokimia, aktivitas antioksidan, dan aktivitas penghambatan tirosinase. Tes aktivitas antioksidan dan penghambatan tirosinase diamati dari nilai IC50 (konsentrasi inhibitor). Hasil analisis fitokimia menunjukkan bahwa ekstrak beras hitam mengandung flavonoid, tanin, dan triterpenoid. Tes aktivitas antioksidan dilakukan dengan menggunakan metode DPPH (2,2-diphenyl-1-picrihydracil) yang memiliki aktivitas antioksidan yang sangat kuat dengan nilai IC < 10 ppm. Ekstrak beras merah memiliki penghambatan tirosinase. Kesimpulan yang di dapat dari penelitian ini adalah ekstrak beras hitam secara fitokimia mengandung flavonoid, tanin, dan triterpenoid yang termasuk ke dalam senyawa antioksidan.
Assumption of heparin-induced thrombocytopenia in mucopolysaccharidoses
Authors: Osipova Liliya Aleksandrovna , Kuzenkova Lyudmila Mikhailovna
Published: September 2021

Background: Mucopolysaccharidoses (MPSs) are a group of lysosomal storage diseases, resulted from glycosaminoglycans’ breakdown failure (GAGs). The study aims to determine the presence of thrombocytopenia, its prevalence, clinical implication, and correlation with the types of MPSs and with the types of glycosaminoglycans storage.

Methods: A retrospective cross-sectional study of complete blood count data was conducted among 108 children with a confirmed diagnosis of MPS in the National Medical Research Center for Children's Health, Moscow, Russian Federation. STATISTICA 10 (Stat Soft, Inc. 1984-2011) was used for statistical analysis. A p-value of ≤0.05 was considered significant.

Results: The median age of children was 65 [IQR: 41; 102] months, range: 3 – 102 months. The male to female ratio was 3:1. The prevalence of fluctuating or persistent thrombocytopenia in all children with MPS was 19.0%. Thrombocytopenia occurred in patients with MPS I (14.0%), II (19.0%), and III (31.0%). Neither of the patients with MPS IV nor VI demonstrated low platelet count. There was a non-significant predominance (P=0.068) of thrombocytopenia frequency in patients with heparan sulfate storage (22.0%) compared with patients without heparan sulfate burden (0%).

Conclusion: Routine checkups of patients with MPSs must include complete blood count with platelet measurement. Cases of thrombocytopenia that requiring treatment, immunomodulatory/ immunosuppressive therapy should be considered. Further research is needed to look for the laboratory confirmation of autoimmune variants of HIT in patients with MPS I, II, III.
Laboratory manifestations of COVID-19 associated with hemostatic abnormalities
Authors: Elsadig Ahmed Elhadi , Ali May Mohammed , Yousif Alfatih Aboalbasher
Published: September 2021

Hemostatic abnormalities had been reported in COVID-19 patients, which may include disseminated intravascular coagulation (DIC), hypercoagulability, and alterations in platelets parameters. Articles that investigate the alterations of hemostatic abnormalities during the COVID-19 disease (2020-2021) and their predictive value of disease outcome have been thoroughly reviewed. Among the reviewed articles, thrombocytopenia is observed in 5.0-41.7% of COVID-19 patients, which is related to disease severity. Moreover, other platelets parameters, including Platelets/lymphocytes ratio (PLR), Mean platelets volume (MPV), and aggregation, may also be affected. On the other hand, findings of coagulation tests such as D dimer; fibrinogen, Antithrombin (AT), and Fibrin degradation products (FDP) are significantly elevated in COVID-19 patients, while in a single study, most of the patients had positive Lupus anticoagulants (LA) and normal protein C (PC). In the same perspective, these alterations showed significant correlations with disease severity. Overall, hemostatic laboratory markers are significant predictors of COVID-19 disease outcome as indicated by the increased risk of venous and arterial thrombotic events, especially in ICU patients.
Utilization of Financial Resources and Development of School Facilities and Services for Students and Teachers of Esperanza National High School
Authors: Karlyn B. Rico MAT
Published: September 2021

This study is a descriptive correlational study which determined the impact of the utilization of financial resources on the development of school facilities and services for students and teachers. Teachers, Supreme Student Council (SSG) Officers, class mayors, student athletes, Parent-Teacher Association (PTA) Officers, disbursing officer, bookkeeper and supply officer were the respondents of this study. They gave a reliable information regarding the utilization of financial resources. Findings revealed that Maintence and Other Operating Expenses (MOOE), Special Education Fund (SEF) and other financial resources were well implemented and the development they have given to the school facilities and services for students and teachers was very satisfactory. Effective utilization of MOOE increased the positive perceptions of the respondents about the welfare and development of school facilities and services for students and teachers in terms of academic achievement and other school performance indicators. Thus, MOOE and SEF should be utilized according to the approved budget where the teachers, PTA officers and School Governing Council (SGC) members will be part of the budget hearing. School administrators should involve all the teachers and some stakeholders in budget planning and implementation and should follow the budget specifications in planning and implementation to avoid diversion of funds.
Imperative Sentences in Java Ngoko in North Sumatra
Authors: Astri Nanda Dwi , Pardede Oktaviandi Bertua
Published: September 2021

This study uses a qualitative method. Qualitative method is a method that uses descriptive methods to describe data by describing related events both in writing and verbally. The research procedure consists of three stages, namely the stage of data collection, data analysis, and presentation of data analysis. The method used in data collection is the method of observing. The technique used in data collection is a free-to-conversation listening technique by observing and recording data in the form of imperative sentences in the Ngoko Javanese language in North Sumatra. The purpose of this study is to increase knowledge and increase understanding of language command sentences   Java Ngoko in North Sumatra. The source of the data in this research is the people in Bandar Tengah village, Bandar Khalipa h, North Sumatra as speakers of the Javanese Ngoko language. Based on the results of the study, imperative sentences in Javanese. Ngoko contain the intent to command, prohibit, invite, order repeatedly, invite, request, be angry, and ask for help.
Development of Agricultural Infrastructure and Material Logistics Support of Farms
Authors:   Namangan Institute of Engineering and Technology, Adashaliyevich Bekmirzayev Mirzohid
Published: September 2021

The article discusses the prospects for the development of entrepreneurship in agriculture in our country, sustainable economic development of farms, which are its main and leading link.
Aportaciones a los estudios de las sexualidades, las identidades y los derechos sexuales y reproductivos
Authors: Ortiz-Ortega Adriana , Rosales Mendoza Adriana Leona
Published: September 2021

Este libro recoge búsquedas interdisciplinarias elegidas para abordar problemas sociales que, por su complejidad y por el reto conceptual y metodológico que plantean, hasta muy recientemente comienzan a ser abordadas dentro del ámbito académico latinoamericano
PENGARUH SISTEM PENGENDALIAN INTERNAL TERHADAP KUALITAS LAPORAN KEUANGAN PADA BADAN PENGELOLAAN KEUANGAN DAN ASET DAERAH PROVINSI JAWA BARAT
Authors: Firmansyah Indra , Sinambela Rani Tarida
Published: September 2021

Sebuah perusahaan dapat dikatakan berkembang bila perusahaan tersebut dapat menampilkan kinerja terbaik dengan sumber daya manusia yang berkompeten agar dapat bersaing sehat dengan perusahaan. Hal ini dapat dilakukan dengan menciptakan sistem yang baik dengan meningkatkan Sistem Pengendalian Internal terhadap Kualitas Laporan Keuangan yang baik diperlukan demi tercapainya tujuan perusahaan. Sistem Pengendalian Internal sangat dibutuhkan untuk kegiatan pengawasan terhadap sistem akuntansi sehigga pada akhirnya akan menghasilkan informasi yang dibutuhkan perusahaan dalam mengambil keputusan serta mendukung fungsi penyediaan pihak manajemen dan mendukung operasional harian perusahaan.Penelitian ini bertujuan untuk mengetahui bagaimana Sistem Pengendalian Internal pada Badan Pengelolaan Keuangan dan Aset Daerah Provinsi Jawa Barat, dilakukan beberapa metode perhitungan yaitu metode perhitungan analisis data atas tanggapan responden, uji validitas dan reliabilitas, koefisien korelasi Rank Speman, regresi linear sederhana dan korelasi determinasi. hasil penelitian untuk hasil uji regresi linear sederhana adalah Yâ€™ = 2.142 + 0,435X, data koefisien tersebut adalah positif sehingga dapat diartikan bahwa adanya pengaruh yang signifikan pada Sistem Pengendalian Internal terhadap Kualitas Laporan Keuangan.
PENGARUH KINERJA KEUANGAN DALAM MEMPREDIKSI PERTUMBUHAN LABA PADA PT POS INDONESIA (PERSERO) CABANG ASIA AFRIKA BANDUNG
Authors: Fatmawati Ade Pipit , Awaru Rala Andi Tenri
Published: September 2021

Analisis laporan keuangan merupakan suatu alat analisis yang digunakan oleh suatu perusahaan untuk melihat ataupun menilai kondisi perusahaan. Salah satunya menilai kinerja keuangan. Analisis tersebut dapat diukur menggunakan analisis rasio keuangan yang terdiri dari rasio net profit margin, return on asset, dan total asset turn over yang dengan rasio-rasio tersebut dapat dievaluasi kinerja perusahaan terhadap prospek laba untuk kedepannya. Tujuan penelitian ini yaitu untuk mengetahui pengaruh kinerja keuangan yang berdasarkan rasio net profit margin, return on asset, dan total asset turn over terhadap pertumbuhan laba pada PT Pos Indonesia (Persero) Cabang Asia Afrika Bandung tahun 2013-2017. Pada penelitian ini, penulis melakukan penelitian dengan menggunakan metode kuantitatif dan metode pengambilan sampel menggunakan teknik purposive sampling. Adapun alat analisis data yang digunakan yaitu uji normalitas data, korelasi product moment analisis regresi linier berganda, koefisien determinasi, uji t, dan uji f. Hasil pengujian koefisien regresi secara parsial menunjukkan bahwa variabel net profit margin berpengaruh signifikan terhadap pertumbuhan laba, return on asset tidak berpengaruh terhadap pertumbuhan laba, dan total asset turn over tidak berpengaruh terhadap pertumbuhan laba. Sedangkan hasil pengujian koefisien regresi secara simultan menunjukkan bahwa net profit margin, return on asset, dan total asset turn over berpengaruh secara simultan terhadap pertumbuhan laba.
PENGARUH REALISASI ANGGARAN BIAYA PRODUKSI DAN REALISASI ANGGARAN PENDAPATAN TERHADAP KINERJA KEUANGAN PERUSAHAAN (GPM) PADA PT PERKEBUNAN NUSANTARA VIII
Authors: Marismiati Marismiati , Zakiyah Rina
Published: September 2021

Realisasi anggaran digunakan untuk menilai baik atau buruknya kinerja keuangan perusahaan. Realisasi anggaran terdiri dari realisasi anggaran biaya produksi dan realisasi anggaran pendapatan. Realisasi anggaran biaya produski dan realisasi anggaran pendapatan berkaitan erat dengan laba perusahaan. Tujuan penelitian ini adalah untuk mengetahui pengaruh realisasi anggaran biaya produksi  dan realisasi anggaran pendapatan terhadap kinerja keuangan perusahaan (GPM) pada PT Perkebunan Nusantara VIII. Metode penelitian yang digunakan yaitu penelitian kuantitatif. Jenis data yang digunakan adalah data primer dengan sampel penelitian yaitu RKAP biaya produksi, RKAP pendapatan dan laporan laba rugi untuk masing masing periode 2010-2017. Hasil penelitian ini menunjukkan secara parsial realisasi anggaran biaya produksi tidak berpengaruh dan tidak signifikan terhadap kinerja keuangan perusahaan (GPM), dan realisasi anggaran pendapatan mempunyai pengaruh signifikan terhadap kinerja keuangan perusahaan (GPM). Kemudian secara simultan realisasi anggaran biaya produksi dan realisasi anggaran pendapatan berpengaruh signifikan terhadap kinerja keuangan perusahaan (GPM) dan didukung dengan nilai koefesien determinasi sebesar 79%.
PENGARUH AKTIVA TETAP DAN MODAL KERJA TERHADAP LABA BERSIH SETELAH PAJAK PENGHASILAN PADA PERUSAHAAN BUMN DIBIDANG PERDAGANGAN (STUDI KASUS PT. PERUSAHAAN PERDAGANGAN INDONESIA (PERSERO), PT . SARINAH (PERSERO) DAN PERUM BULOG) 2012-2016
Authors: Satria M Rizal , Thamrin Titani An Niza
Published: September 2021

Setiap perusahaan pada umumnya didirikan untuk menghasilkan keuntungan yang lebih atas investasi yang telah ditanamkan untuk kelangsungan hidup usaha dan perkembangan perusahaan itu sendiri, dan menghasilkan keuntungan atau laba menjadi perhatian utama dalam setiap perusahaa. Penelitian ini bertujuan untuk mengetahui pengaruh aktiva tetap dan modal kerja terhadap laba bersih setelah pajak penghasilan perusahaan BUMN dibidang perdagangan. Metode yang digunakan adalah kuantitatif bersifat asosiatif. Sumber data dalam penelitian ini adalah primer dengan sampel laporan keuangan tahun 2012-2016. Berdasarkan hasil analisis diperoleh korelasi  sebesar 0,658 hal ini menunjukkan hubungan yang kuat antara variabel independen yaitu aktiva tetap (X1) dan modal kerja (X2) terhadap variabel dependen yaitu laba bersih setelah pajak penghasilan (Y). Hasil uji t statistik menunjukkan bahwa secara parsial aktiva tetap berpengaruh negatif signifikan terhadap laba bersih setelah pajak penghasilan, dan secara parsial modal kerja berpengaruh positif signifikan terhadap laba bersih setelah pajak penghasilan.
PENGARUH BUDAYA ORGANISASI, MOTIVASI DAN PROFESIONALISME TERHADAP KINERJA AUDITOR INTERNAL (Survey pada BUMN Sektor Jasa Keuangan & Asuransi di Kota Bandung)
Authors: Lisda Ruslina , Sukesih Sukesih
Published: September 2021

This study aims to examine and analyze how much influence Organizational Culture, Motivation and Professionalism to the Performance of Internal Auditors. Population in this research is Internal Auditor and Internal Supervision Unit in the State Industry Companies financial and insurance services in Bandung City. The number of seals taken as many as 46 respondents. The research method used is descriptive and verification method. Data collection techniques are done through primary data with questionnaires. Sampling technique using Probability Sampling technique using Simple Random Sampling method. Statistical analysis used in this research are validity test, reliability test, multiple correlation analysis, multiple regression analysis, T test, F test, and coefficient of determination. Simultaneously shows that the magnitude of the influence of organizational culture, motivation and professionalism to the performance of internal auditors of 70,7%, while the rest of 20,3% influenced by other factor not observed in this research. Thus, the higher the organizational culture, motivation and professionalism will further improve the performance of internal auditors.
ANALISIS POTENSI PAJAK RESTORAN KABUPATEN GARUT
Authors: Romdhon Mochamad , Siska Dellya
Published: September 2021

Pajak Restoran di Kabupaten Garut diatur dalam Peraturan Daerah Kabupaten Garut Nomor 1 Tahun 2016. Dari segi kewilayahan, Kabupaten Garut mempunyai wilayah yang luas dengan bermacam-macam aneka kekayaan alam yang ada didalamnya. Kabupaten Garut memiliki alam yang masih alami sehingga bisa dikembangkan menjadi objek wisata alam. Dalam rangka pelaksanaan kepemerintahan di Kabupaten Garut sesuai kewenangannya, salah satu pendukung untuk terlaksananya pemerintahan harus didukung dengan pembiayaan yang memadai. Salah satu sumber pembiayaan yang dapat diperoleh Pemerintah Kabupaten Garut adalah melalui penerimaan pajak daerah yang salah satunya adalah pajak restoran. Tujuan penelitian ini adalah untuk mengetahui bagaimana potensi pajak restoran di Kabupaten Garut. Metode yang digunakan adalah metode deskriptif, teknik pengumpulan data menggunakan penelitian kepustakaan dan penelitian lapangan dengan survey, wawancara, studi pustaka dan observasi langsung. Teknik pengolahan data yang digunakan adalah analisis data kualitatif yang meliputi reduksi data, penyajian data, dan penarikan kesimpulan.
INFLUENCE OF PROJECT MANAGEMENT INFORMATION SYSTEM ON CREDIT DIGITIZATION IN COMMERCIAL BANKS IN NAIROBI, KENYA
Authors: KAMAU JEREMIAH , Pedo Maurice
Published: September 2021

Purpose:  Therefore, the study sought to establish the influence of PMIS on credit digitization in commercial banks in Kenya.

 Methodology: The target population for the study was the 42 commercial banks in Kenya. The study employed a descriptive survey design and was census of the 42 commercial banks head offices in Nairobi, Kenya. Data was collected by use of a structured questionnaire. The data was cleaned, coded and analyzed using a Statistical software (SPSS). The findings were presented in form of tables, charts and graphs. Descriptive statistics were deduced from the data. From this, inferential statistics were presented and associations drawn. Regression analysis was interpreted and appropriate conclusions made.

Findings: The findings from regression analysis showed that expertise of the project team, end-user involvement, project risk management and project monitoring and evaluation positively and significantly influence credit digitalization in Kenyan Commercial banks.  

Unique contribution to theory, practice and policy: The study was guided by the lenses of Stakeholder Management theory, Technology Acceptance Model (TAM) and the Theory of Disruptive Innovation from which the study operationalized the variables of PMIS Implementation and Credit Digitization. Banks should conduct training to all team members before commencement and during project execution. Moreover banks should involve customers in testing of projects before launching and should consider the feedback from customers
VARIABILIDADE INTERANUAL DO BALANÇO HÍDRICO EM LAGOA SECA, PARAÍBA – BRASIL
Authors: Rodolfo de Araújo Wagner , Mainar de Medeiros Raimundo , Morant de Holanda Romildo , Marcelo Falle Saboya Luciano , Vieira de França Manoel , Cartaxo Rolim Neto Fernando
Published: September 2021

Tem-se por objetivo avaliar os balanços hídricos anuais do período 1981-2019, e suas oscilações pluviais, evaporativa e evapotranspirativa, além das reposições, retirada, deficiência e excedentes hídricos interanuais. Os dados pluviais médios mensais em estudos foram caracterizando como um período de normal climatológica, onde, empregou-se do software em planilhas eletrônicas, para extrair os valores das médias mensais e anuais da precipitação do período de 1981 a 2019. Os dados térmicos foram estimados pelo software estima_T, para o mesmo período pluvial. O balanço hídrico foi computado pela metodologia de Thornthwaite. Os anos que o poder evapotranspirativo foi maior que os índices pluviais registram- se em: 1983-1988; 1990 a 1992; 1994; 1996; 1998; 2000; 2008; 2009 2011 e 2019. Os índices evaporativos igualaram-se ou fluíram abaixo da pluviometria anual foram: 1981; 1993; 1999; 2004; 2006; 2007; 2012 e 2015. Recomenda-se o auxílio da irrigação mesmo nos períodos de chuva irregulares pois o poder evaporativo e evapotranspirativo superam os índices pluviais.
Designing a neighborhood centre with the approach of improving the lifestyle of residents (Case study: Kandahar New Town neighborhood centre)
Authors: ارغستانی عبدالرحمن
Published: September 2021

از عناصر تشکیل‌دهنده فضاهای شهری، محلات شهری می‌باشند که یکی از عناصر مشترک شهر بوده، بی‌تردید روابط متقابل ما با دیگران نقش مهمی در اولویت‌هایمان در سکونت‌گاه دارد و محیط شناخته‌شده باید بتواند نیازهای مربوط به این روابط را پاسخ گوید. از سوی دیگر می‌دانیم که فضاها، نقش اجتماعی خاصی را بر ساکنان خود تحمیل می‌کنند و برخی الگوها و معیارهای رفتاری را تقویت و برخی دیگر را تضعیف می‌کنند و درنهایت جهت و ابعاد جدیدی به رفتارهای ساکنان خود می‌بخشد. عطف به این مفاهیم و با نظری به معماری گذشته درمی‌یابیم که در آن معماری، این نیازها نیاز به تعاملات اجتماعی و ارتباط با همنوعان، حفظ حریم، در جای خود به‌خوبی پاسخ می‌گرفتند، به‌گونه‌ای که تأمین، تعریف و شفافیت مناسب قلمروهای خصوصی و عمومی، همراه با افزایش تعاملات اجتماعی مدنظر قرار داشتند. روش تحقیق در این پژوهش از نوع تحلیلی کاربردی بوده که با استفاده از روش گردآوری اطلاعات به شیوه میدانی و کتابخانه‌ای و تجزیه‌وتحلیل داده‌ها انجام گرفت. درروش میدانی با استفاده از روش برداشت و تکمیل پرسشنامه اطلاعات گردآوری‌شده. حجم نمونه جامعه موردمطالعه (محله شهر نو قندهار) ۱۰۰ نمونه به دست آمد، داده‌های گردآوری‌شده در نرم‌افزارSPSS پیاده شده و با استفاده از آزمون آماری و نسبت و فریدمن تجزیه‌وتحلیل داده‌ها و آزمون فرضیات صورت گرفت. نتایج حاصل از این تحقیق نشان می‌دهد که متغیرهای تعاملات اجتماعی، عامل روانی – اجتماعی و ساختار کالبدی فضایی در ارتقاء سطح تعاملات اجتماعی و کیفیت طراحی مرکز محله رابطه مستقیم و معناداری وجود دارد.
Editorial: mundos imaginados
Authors: Lorenzo Hernández María
Published: September 2021

Editorial del decimotercero número de Con A de Animación
European Contract Law
Authors: Schulze Reiner , Zoll Fryderyk
Published: September 2021

European contract law is not only a key aspect of European private law but also plays a highly important role in the development of contract law at national level. However, European contract law is often an unfamiliar subject as its content, methods and objectives are overshadowed by national laws.

This book therefore provides fundamental information about the content, methods and objectives of European legislation in the field of contract law and explains the interaction between the legislator, judges and academics during the creation of European contract law. It attempts to show how a system arises from the dialogue between the different sources. It therefore focusses not only on current EU legislation but also the extensive preparatory works in which the authors of this book were actively involved.
Left Behind: Labor Unions and Redistributive Policy under the Brazilian Workers' Party
Authors: Schipani Andrés
Published: September 2021

How do leftist governments negotiate the trade-off between courting union support and maintaining the business sector's trust? Scholars have argued that leftist parties will remain accountable to their labor base when powerful unions have strong ties to centralized leftist parties.
However, I argue that strong party-union ties and party leadership centralization may, in fact, insulate leftist presidents against redistributive pressures from below. When party-union ties allow labor leaders to develop careers as professional politicians, these leaders become more responsive
to the party's goals than to their union base. Further, a centralized party organization can exclude unions and leftist factions from the design of redistributive policies. To test my argument, I use a case study of Brazil under the administration of the Worker's Party (PT).
The Influence of Lecturer Competence, Self-Efficacy and Motivation on Student Achievement of the Faculty of Economics and Business, Warmadewa University
Authors: Martadiani AA Media , Azita Aziz Ita Silvia , Niti Widari Dewa Ayu
Published: September 2021

This study aims to analyze the mediating role of self-efficacy and motivation between lecturer competencies, on student achievement in the Faculty of Economics and Business, Warmadewa University. The sample used in this study were 93 students. Research resultshows that all variables have a positive and significant effect on student achievement. Self efficacy and motivation fully mediate between lecturer competence and student achievement.
Impacts of Parental Involvement on English Language Learning of Vietnamese Secondary School Students: Understanding Parents’ Perceptions
Authors: Le Nhu Quynh , Phuong Nguyen Hong Thi
Published: September 2021

This paper reports a descriptive study that examined Vietnamese parents’ perceptions of the impacts of their parental involvement on their children’s English language learning at secondary school. It draws on data collected as part of a larger project. Data were collected using including a questionnaire and semi-interviews and analysed using descriptive statistics. Findings reveal that parents held positive perceptions of their involvement on their children’s English language learning outcome. Implications for practical applications of parental involvement are also presented.