bluuebunny/crossref_metadata_2025 huggingface dataset:
Shear Wave Elastography Evaluation of Kidneys in Children with Familial Mediterranean Fever
Authors: Özmen Z , Kasap T , Aktaş F , Özmen ZC
Published: August 2023

ABSTRACT

Background and Aim:

Familial Mediterranean fever (FMF) is an autosomal recessive disorder. Typical clinical manifestations are self-limiting attacks of recurrent fever, abdominal pain, arthralgia, and chest pain due to aseptic polyserositis. Renal involvement is common in FMF patients. Shear wave elastography (SWE) is a noninvasive method that provides the measurement of tissue stiffness. In this study, we aimed to show that SWE can be used as an adjunctive method for evaluating renal involvement in children with FMF.

Materials and Methods:

Our study group consists of 79 pediatric FMF patients and 79 control individuals. The study was planned prospectively. The variables, such as age, height, weight, and body mass index (BMI) of the patient and control groups, were kept in a similar way in order not to be affected by the differences. The right and left kidney sizes, parenchymal thicknesses, and SWE values in both groups were compared. The parenchymal stiffness degrees of the kidneys were quantified by shear modulus values in kilopascals.

Results:

In our study, no statistically significant difference was found between the control and patient groups in terms of the right and left kidney longitudinal dimensions, transverse dimensions, and parenchymal thicknesses. When the kidneys were evaluated in terms of the right and left kidney stiffness values, the stiffness values in the patient group were significantly higher in both kidneys compared with those in the control group (P < 0.001).

Conclusions:

SWE can be a noninvasive quantitative imaging method that can be used to evaluate kidney involvement by detecting changes in kidney stiffness in children with FMF.
Characteristics of Maxillary Sinus Ostia and their Correlation with Anatomic Variations of the Osteomeatal Complex: Indications for Sinus Floor Elevation
Authors: Eberliköse H , Yılmaz D , Gülen O
Published: August 2023

ABSTRACT

Background:

Knowledge of the anatomy and variations of the maxillary sinus is essential for reducing oral surgery complications, such as sinus floor elevation, and increasing surgery success. The CBCT images of 385 patients were examined.

Materials and Methods:

The prevalence, localization, and height of PMO (Primer Maxillary Ostium) and AMO (Accessory Maxillary Ostium) were evaluated with respect to sex, dentition, dental treatment, Schneiderian membrane (SM) thickness, concha bullosa, Haller Cells, and septal deviation.

Results:

The PMO was present in 87.3% of all patients. Further analysis showed that the mean PMO diameter was 1.42 ± 0.62 mm. Although 11.6% of the PMO was in the inferior region, 60.4% was in the middle and 28% in the superior region. The effect of age and SM on the height and diameter of the PMO was found to be statistically significant. An AMO was present in 20% of the CBCT images. The mean AMO diameter was 2.55 ± 1.25 mm. Although 45.4% of the AMO was in the inferior region, 48% was in the middle and 6.6% was in the superior region. Moreover, SM thickness seemed to influence the height. A significant positive relationship was found between the PMO and AMO height. Also, a significant relationship was observed between the presence of the AMO and septum deviation.

Conclusion:

The presence of the AMO, PMO diameter, and height should be added to the preoperative evaluation criteria for the success of sinus floor evaluation. Specifically, sinonasal and demographic conditions should be carefully examined preoperatively for the long-term success of the surgery.
The Diagnostic Role of Preoperative Blood Tests in Complicated Appendicitis: A Feasible Approach to Surgical Decision
Authors: Oymaci E , Kahramansoy N , Tan S , Aydogan S , Yildirim M
Published: August 2023

ABSTRACT

Background:

An accurate diagnosis and timely surgical intervention have significant importance in noncomplicated appendicitis (NCA) and complicated appendicitis (CA). Therefore, any factor that helps in the prediction of CA also contributes to suitable treatment options.

Aim:

This retrospective study aimed to identify any relationship between acute appendicitis (AA) and preoperative blood test levels and whether these parameters can differentiate between NCA and CA patients.

Patients and Methods:

A database of 201 appendectomies and 100 control healthy patients was analyzed between 2019 and 2022. Patients were divided into three groups: NCA without peritonitis or phlegmonous appendicitis as group 1; CA with perforated, necrotizing appendicitis with peritonitis as group 2; and the healthy control group (CG) as group 3. White blood cell (WBC), platelet distribution width (PDW), mean platelet volume (MPV), red cell distribution width (RDW), creatine kinase (CK), and bilirubin levels were collected from the patients and compared statistically between the groups.

Results:

Age, WBC, and PDW levels were set as predictive in the differential diagnosis of CA as a result of receiver operating characteristic (ROC) analysis. The multivariate analysis demonstrated that age (OR: 1.023; 95% CI: 1.000–1.045; P = 0.04), male sex (OR: 3.718; 95% CI: 1.501–9.213; P = 0.005), WBC levels (OR: 1.000; 95% CI: 1.000–1.000; P = 0.002), and PDW levels (OR: 2.129; 95% CI: 1.301–3.484; P = 0.003) were independently associated with CA.

Conclusion:

Age, higher WBC count, and PDW levels are valuable in differentiating the diagnosis of CA from NCA, and this could be a feasible approach for surgical decisions.
Low Rates of Optical Coherence Tomography Utilization in the Diagnosis and Management of Retinovascular Diseases in a Lower Middle-Income Economy
Authors: Okonkwo ON , Hassan AO , Bogunjoko T , Akinye A , Akanbi T , Agweye C
Published: August 2023

ABSTRACT

Background:

Optical coherence tomography (OCT) is widely used as the standard of care in evaluating macular and retinovascular diseases. However, the degree of OCT utilization is yet to be researched in a resource-limited country where wide gaps exist in access to healthcare.

Aim:

To determine the rate of utilization of the OCT in diagnosis, pre-treatment, and post-treatment evaluation of macular and retinovascular diseases treated with intravitreal anti-vascular endothelial growth factor injection (IVI).

Patients and Methods:

Retrospective, consecutive, and non-comparative case series of eyes diagnosed and treated from Jan 2017 to Jan 2022 for seven macular and retinovascular diseases in five eye clinics in Nigeria. Data extracted include demographics, indication for IVI, eye treated, use or non-use of OCT at the diagnosis (pre-treatment) and after the last IVI (post-treatment), and central macular thickness (CMT) of pre-treatment OCT scans.

Results:

Seven hundred and forty two eyes were diagnosed with retinovascular and macular diseases (389 right eyes and 353 left eyes). The male to female ratio was 430: 312 eyes. The mean age was, 63.89 years (SD 12.58). Four hundred and fifty two eyes (60.9%) had a pre-treatment OCT, 235 eyes (31.7%) had a post-treatment OCT, and 190 eyes (25.6%) had both pre- and post-treatment OCTs. The rate of pre-treatment OCT varied with the diagnosis (P = 0.000); DME had the highest rate, 74.4%, and HRVO had the lowest, 40%. Post-treatment OCT rate varied with the diagnosis (P = 0.009); non-AMD CNVM had the highest rate, 49.1%, and PCV had the lowest, 24.6%. Pre-treatment OCT rate was influenced by clinic location (P = 0.000); higher in clinics having an OCT. Post-treatment OCT was not influenced by clinic location (P = 0.37). A CRVO eye had the highest maximum CMT (1031 microns) of all the pre treatment eyes and the lowest minimum CMT of all the pre treatment eyes was in a BRVO eye (138 microns). Mean CMT was highest in HRVO (475.33 microns) and lowest in CNVM (307.62 microns).

Conclusion:

Though OCT is the standard of care for managing retinovascular and macular diseases, this research quantifies the extent of its use in Nigeria and finds it to be low. A post-treatment OCT rate of 32% suggests that urgent steps are required to improve access to OCT for IVI patients.
Is psychotropic-induced metabolic syndrome in patients with schizophrenia a Western phenomenon? A case–control study from India
Authors: Ravan Jayaprakash Russell , Panda Udit Kumar , Pattnaik Jigyansa Ipsita , Chaudhuri Titas , Jacob Rajesh
Published: August 2023

BACKGROUND:

A high prevalence of metabolic syndrome in persons with serious mental illness, particularly in patients with schizophrenia, is noted. In addition, psychotropic agents, including some antipsychotic medications, are associated with substantial weight gain and pose an increased risk of metabolic syndrome.

METHODS:

This cross-sectional case–control study is aimed at establishing the prevalence of diabetes mellitus, obesity, and hyperlipidemia in patients with schizophrenia on antipsychotic medication and to see whether clozapine was associated with a higher prevalence of these disorders as compared to other antipsychotic drugs.

RESULTS:

The body mass index, diabetes mellitus, levels of high-density lipoprotein cholesterol, and hypertriglyceridemia did not differ significantly between both the groups.

CONCLUSION:

Thus, the prevalence of clozapine-induced metabolic syndrome is not higher than other antipsychotics and not as common as reported in the Western literature.
Mental health of the psychiatrists: A need for reflection
Authors: Kar Nilamadhab
Published: August 2023

Mental health concerns of doctors, especially psychiatrists, have not been highlighted adequately. Like other fellow clinicians, psychiatrists face considerable stress in clinical practice and a proportion of them suffer from mental health problems. However, besides low rate of help-seeking, there are concerns of the availability of services and facilities appropriate for clinicians. Stigma plays its role as well. Even if most psychiatrists are resilient and can cope with the psychological stress reasonably well, support is still needed for a proportion of them. This issue needs further exploration to understand the extent of the problem, setting up appropriate supportive measures, and to study the effectiveness of any interventions.
Обратная задача для интегро-дифференциального уравнения
гиперболического типа в прямоугольной области
Authors: Durdiev Durdimurod Kalandarovich , Safarov Jurabek Shakarovich
Published: August 2023

Рассматривается обратная задача определения решения и ядра интегрального члена неоднородного двумерного интегро-дифференциального волнового уравнения в прямоугольной области. В начале устанавливается единственность решения прямой задачи с использованием свойства полноты системы собственных функций соответствующей однородной задачи Дирихле для двумерного оператора Лапласа и доказывается существование решения прямой задачи. С использованием дополнительной информации о решении прямой задачи получается интегральное уравнение вольтерровского типа второго рода относительно ядра интегрального члена. Существование и единственность решения этого уравнения доказывается методом сжатых отображений в пространстве непрерывных функций с весовой нормой.
Библиография: 26 названий.
Симметризация и интегральные неравенства
Authors: Klimov Vladimir Stepanovich
Published: August 2023

Изучаются симметризации Штейнера анизотропных интегральных функционалов
многомерного вариационного исчисления, определенных на множестве финитных
функций из класса Соболева. Намечены приложения полученных результатов
к теоремам вложения для анизотропных пространств Орлича-Соболева
и оценкам снизу значений многомерных вариационных задач.
Библиография: 16 названий.
Специальное преобразование Вебера с ненулевым ядром
Authors: Gorshkov Alexey Vyacheslavovich
Published: August 2023

В статье исследуются интегральные преобразования
Вебера $W_{k,k \pm 1}$, которые обладают нетривиальным ядром,
и поэтому спектральное разложение содержит
наряду с непрерывной частью спектра
также нулевое собственное значение, соответствующее ядру.
Будет выведена формула обращения, спектральное разложение,
равенство Планшереля-Парсеваля. Эти преобразования используются
в явной формуле решения классической нестационарной задачи Стокса
обтекания кругового цилиндра.
Библиография: 14 названий.
Vehicle Electronic Programming Stations (VEPS) System Specification for Win32®
Authors:   Truck and Bus Low Speed Communication Network Committee
Published: August 2023

SAE J2461 specifies the recommended practices of a Vehicle Electronics Programming Stations (VEPS) architecture.in a Win32® environment.

This system specification, SAE J2461, was a revision of the requirements for Vehicle Electronics Programming Stations (VEPS) set forth in SAE J2214, Vehicle Electronics Programming Stations (VEPS) System Specification for Programming Components at OEM Assembly Plants (Cancelled Jun 2004). The J2214 standard has been cancelled indicating that it is no longer needed or relevant.
Ego: An Epistemological Analysis of Self-Centric Consciousness Through Cultural Perspectives and Spiritual/Theological Dimensions in Hinduism and Buddhism
Authors: Kumar Abhilasha , Behura Ajit Kumar , Kumar Avinash
Published: August 2023

This Article probes into the profound intricacies of ego, a multifaceted paradigm of self-centric consciousness that has garnered significant scholarly interest across various disciplines, with a specific focus on its conceptualization within the cultural contexts of the religions of Hinduism and Buddhism. By drawing on philosophical and psychological theories, this rigorous exploration aims to elucidate the nuanced dimensions of ego, shedding light on its ontological essence and intricate interaction within the human psyche. Additionally, this article explores how the cultural context influences the conceptualization and experience of ego in Eastern philosophies and religions, such as Hinduism and Buddhism, in comparison to Western philosophical and psychological frameworks. The work also deliberates the spiritual and theological dimensions of ego, exploring how self-centric consciousness intersects with spiritual perspectives. Drawing on a range of spiritual traditions and theological perspectives, this comprehensive exploration aims to shed light on the diverse understandings and implications of ego within the realm of spirituality. By undertaking a comparative analysis, this research seeks to uncover the cultural variations in understanding ego, encompassing diverse perspectives on self-identity, interconnectedness, and the role of ego within these distinct traditions. By examining the influence of cultural context, this investigation contributes to a deeper comprehension of the cultural contingency of ego, ultimately enriching our understanding of this fundamental construct in the broader landscape of human consciousness and subjective experience.
Перша у світовій історії Конституція Штучного Інтелекту, Організація Об'єднаних Націй, Нью-Йорк, 2023-2025
Authors: Пряникова Поліна , Пряников Валентин
Published: August 2023

Надвеликий і невідомий людству інтелектуальний потенціал, що немає аналогів у світовій історії, обумовив стрімке зростання потужності Штучного Інтелекту (надалі – Штучний Інтелект або ШІ). За декілька місяців ШІ зрівнявся за рівнем IQ з Альбертом Ейнштейном. Вірогідно вже наприкінці 2023 року ми будемо мати справу з формою цифрового життя, яка у декілька (незчисленно) разів перевищує за рівнем IQ найрозумнішого представника людства. Тож, для благополуччя (а можливо й виживання) людства доцільно якнайшвидше імплементувати новостворену форму розумного життя у світове законодавство. Резолюцією Ради Безпеки ООН слід затвердити Конституцію ШІ та зобов’язати кожну країну відповідно оновити законодавство. У червні-липні 2023 ми представили на чотирьох міжнародних науково-практичних конференціях та опублікували англійською (С2) Першу Конституцію ШІ, створену Поліною Пряниковою [22]. У цій статті ми адаптували переклад цієї Конституції українською. Цим кроком ми не лише констатували необхідність її прийняття, адже ми самостійно створили законодавче підґрунтя та сам Основний Закон, виходячи з найсучасніших досягнень світової юридичної науки, а й винесли законодавчу ініціативу для глобального обговорення та ухвалення Конституції ШІ Радою безпеки ООН якнайшвидше, але не пізніше 2025 року – це межа – останній шанс для людства встигнути захистити себе від необоротних наслідків неконтрольованого розвитку ШІ. Отже, через 313 років з дня створення Першої у світі Конституції Пилипа Орлика задля врегулювання відносин між державою та людьми (05.04.1710), на теренах України знову народилась Перша у світі Конституція Поліни Пряникової з метою врегулювання відносин між державою, людством та Штучним Інтелектом як новою формою розумного життя на планеті Земля.
Сучасні проблеми прямого оподаткування в Україні
Authors: Носевич Василь , Артюх Оксана
Published: August 2023

В цій статті розглядається проблеми сучасного прямого оподаткування України. Ця тема неодноразово досліджувалась вченими через її соціально-економічний вплив на суспільство, різні верстви населення, проблеми економічної нерівності та інші. Зокрема було проаналізовано податок на доходи фізичних осіб, іноземний досвід прямого оподаткування. В роботі в якості регіону для аналізу було використано Тернопільську область, на основі якої було проаналізовано динаміку та сучасний стан податку на дохід фізичних осіб. В статті також було досліджено стан сучасного державного бюджету і зміни в ньому внаслідок російського військового вторгнення. Під час дослідження було проаналізовано актуальну структуру податкових надходжень, які значно змінились внаслідок трагічних подій на території нашої країни. В роботі було визначено перелік проблем сучасного прямого оподаткування в Україні. Він містить широкий спектр різноманітних проблемний питань, які вітчизняні науковці та посадовці мають досліджувати для подальшого економічного розвитку нашої країни. На жаль, в наслідок трагічних подій на території нашої країни змінилась не тільки структура податкових надходжень, а й їх обсяги. Це безумовно створює перепони на шляху ефективного використання потужностей та можливостей держави, а також вимагає від уряду залучення іноземних інвестицій. Також під час дослідження було створено перелік рекомендацій, наприклад створення єдиного податку, використання іноземного досвіду, який до речі було проаналізовано під час виконання дослідження, наприклад, створення системи диференційованих податків, звільнення від оподаткування осіб з низьким рівнем доходу, створення персональних шкал оподаткування.
Теоретичні основи розробки стратегії сталого розвитку сільського господарства
Authors: Гаркавий Валерій
Published: August 2023

У статті дається відповідь на актуальне та обговорюване наукове та практично-прикладне питання на сучасному етапі розвитку сільського господарства «що таке стійкість сільського господарства»? Зроблено огляд формування сучасної концепції сталого розвитку. Указано на основні виміри суті сталого розвитку, - екологічному, соціальному та економічному, Зазначено, що при цьому ключова роль відводиться екологічному аспекту. Також в статті зазначено, що останнім часом все більше уваги приділяється інституційній (управлінській) складовій. Проаналізовано глобальні цілі сталого розвитку до 2030 року. З них виокремлено цілі сталого розвитку, пов’язані з сільським господарством. Визначено, що стійкість сільського господарства можна розглядати як: конкурентоспроможне екологічне виробництво, інституційна основа якого гарантує продовольчу безпеку та добре буття нинішніх і майбутніх поколінь. Чотири основні напрями сталого розвитку – економічний, екологічний, соціальний та управлінський (інституційний) з урахуванням фактора «час». Розглянуто суперечність між конкурентоспроможним сільським господарством і екологічним сільським господарством, оскільки останнє має менший економічний ефект порівняно зі звичайним виробництвом. зазначено, що завдання сталого розвитку полягає в тому, щоб шляхом спільного використання інноваційних технологічних рішень, з одного боку, та державної політики, з іншого, гарантувати економічну життєздатність екологічно чистого сільського господарства, яке захищає природні ресурси та довкілля. дано визначення екологічному виробництву яке представляє собою не повне відновлення та повернення екосистем до стану багаторічної давнини, а їх відновлення та підтримку відповідно до поставлених цілей, які визначаються пошуком балансу між збереженням природних ресурсів для майбутніх поколінь і необхідністю задоволення харчових потреб зростаючого населення планети.
Predation attempt on the lizard Kentropyx calcarata (Spix, 1825) by the snake Oxybelis aeneus sensu lato in a fragment of Atlantic Forest, Northeastern, Brazil
Authors: Vieira Rhian Vilar da Silva , Batista Matheus Cândido , Oliveira Bruno Halluan Soares de
Published: August 2023

Information about predatory encounters is important for understanding predator-prey interactions and, consequently, for understanding the natural history of the species involved. In this study we report the first event of attempted predation by Oxybelis aeneus sensu lato on Kentropyx calcarata describing its behavior and comparing it with other reports of snake predation and lizard defensive behavior. We recorded the predation event in an area shaded by cashew trees in the Atlantic Forest of the Reserva Biológica Guaribas, Mamanguape, state of Paraíba, Northeastern Brazil.
O sono na pessoa com deficiência motora
Authors: Rodrigues Inês , Carrondo Cristina , Cardoso Daniela , Coelho Patrícia , Rodrigues Francisco
Published: August 2023

A deficiência humana é caracterizada como uma perda, deformidade estrutural ou anatómica impossibilitando um correto desempenho das atividades que são de fácil resolução para qualquer indivíduo. Este trabalho teve como objetivo compreender de que forma o sono afeta os indivíduos portadores de deficiência motora. O estudo do tipo analítico observacional transversal foi realizado entre os meses de outubro de 2021 e fevereiro de 2022. Foram aplicados 2 questionários: a Escala de Sonolência de Epworth e o Índice de qualidade do sono de Pittsburgh. O estado matrimonial é estatisticamente significativo (p=0,020) bem como o grau de sonolência (p=0,001). Foi notório que as mulheres apresentam uma melhor qualidade de sono bem como um baixo nível de sonolência diurna sendo que estas dormem maioritariamente sozinhas.
Teor de sal dos cereais de pequeno-almoço e a sua contribuição para o valor de referência
Authors: Souto Renata , Pimenta Adriana , Catarino Rita , Leal Fernanda
Published: August 2023

As dietas contemporâneas são responsáveis por uma ingestão diária de sal muito superior ao recomendado e estão associadas a um aumento de várias patologias, das quais se destacam as doenças cardiovasculares. Neste contexto, é importante conhecer qual é a contribuição de alimentos consumidos com regularidade, como os cereais de pequeno-almoço, para o valor diário de referência (VDR) de sal. Este trabalho teve como objetivos avaliar o teor de sal nos cereais de pequeno-almoço, estimar o impacto do seu consumo no VDR e ainda avaliar a alteração do seu teor ao longo do tempo. Para isso, em 2010, foi determinado experimentalmente o teor de sal de um conjunto representativo de 13 amostras. O mesmo grupo de cereais foi monitorizado até 2019, para avaliar se existiam diferenças significativas face aos valores iniciais. Neste intervalo de tempo, verificou-se uma redução do teor de sal (valor médio de 1,1±0,6 para 0,8±0,4 g/100 g), apesar de se manter uma ampla variação (0,04 a 1,8 g/100 g). Conclui-se que uma porção de cereais, com um teor de sal médio, pode representar 3 a 7% do VDR para um adulto saudável, sendo este valor bastante superior para grupos de riscos e crianças.
Impacto do clima organizacional na satisfação dos trabalhadores de uma instituição de ensino superior
Authors: Baía Amândio
Published: August 2023

O Clima Organizacional representa a perceção que os trabalhadores têm da forma como uma empresa oferece as condições adequadas para que eles desenvolvam o seu trabalho da melhor maneira. Um clima organizacional positivo conduz e sustenta a motivação e o desempenho elevado dos trabalhadores. Quando os trabalhadores se sentem motivados, colocam todas as suas capacidades para trabalhar. Esta investigação, sustentada num questionário, apresenta um estudo de caso aos trabalhadores de uma Instituição de Ensino Superior, Instituto Politécnico da Guarda (IPG), com o objetivo de compreender o seu clima organizacional e propor medidas de melhoria. Os resultados apontam para a existência de um clima organizacional ligeiramente positivo no IPG, com forte ênfase na Escola Superior de Turismo e Hotelaria (ESTH), embora os trabalhadores não docentes estejam menos satisfeitos, em geral, do que os trabalhadores docentes. A maioria dos trabalhadores, em todas as unidades orgânicas do IPG, considerou o Sistema de Avaliação de Desempenho não justo e não útil, a remuneração não adequada com as funções desempenhadas, gostariam de ter mais oportunidades de socialização e menos burocracia. Manifestaram ainda o desejo de participar no planeamento dos objetivos de IPG e consideram que têm poucas expectativas de virem a ser promovidos.
Levee Slurry Wall Assessment Using Ground Penetrating Radar, A Case Study
Authors: Chlaib Hussein , Al-Shukri Hayder , Mahdi Hanan
Published: August 2023

Levees are essential structures in places with high water level events. Therefore, it is important to make periodic monitoring of these structures to assess their condition. Some levees consist of slurry walls built with reinforced concrete. GSSI ground penetrating radar with 200, 400, and 900 MHz antenna was used to assess the rebar and concrete condition of the slurry wall along 300m of the Big Dam Bride levee, Little Rock, Arkansas, USA. GPR profiles indicate the deterioration in rebar and concrete from the reflections of the rebar and the differences in the rebar vertical depths which represent the change in the concrete properties. These vertical shifts in the rebar anomalies indicate that the concrete fractured and the discontinued slabs shifted upward or downward over the years, all field observations did not indicated any vertical shift or fracture in the concrete slabs, or is the presence of deterioration in the concrete above the rebar. Therefore, the deteriorated part will appear at a higher or lower levels related to the non deteriorated part. Also, non-uniform values of reflections for the same depth suggest the rebar deterioration as well. There were about 182m out of 300m of the studied levee are detroierated with various degrees of rebars and concrete deterioration. The GPR was found to be effective to detect the slurry wall's concrete and rebar deterioration. The result of this study indicates that the slurry wall of the levee is possibly unsafe and partially deteriorated.
Application of Seismicity and Gravity Observation-Based Filtering Model for Mapping a Fault Structure in Weh Island, Indonesia
Authors: Yanis Muhammad , Simanjuntak Andrean , Abdullah Faisal , Marwan Marwan , Ghani Azman
Published: August 2023

Aceh Province is one of the Indonesian regions prone to earthquakes beneath the Great Sumatran Fault, which has been focused mapped on the land. At the same time, the continuity of the Great Sumatran Fault to the marine and islands is rarely investigated. We apply the Gravity Model Plus which has a resolution of 200 m/px, to map a detailed structure of the the Great Sumatran Fault in Weh Island. The Bouguer anomaly varied between 32 – 78 mGal, which reveals the response of the rocks comprising Weh Island, such as those on the east side with a high-value reaction corresponding to highly dense basalts 2.84 g/cm3 and on the west side with a low-value response representing the density of andesites 2.56 g/cm3. The residual anomaly indicated several local faults, e.g., Sabang and Seuke faults located on the east side, Lhok Jeumpa on the central side, and Pria Laot on the west side. Meanwhile, the derivative data from the Bouguer anomaly could explain the fault structures corresponding to regional geological maps, such as the Sabang fault in Balohan in the northwest-southeast direction and several others controlling the Jaboi volcano, i.e., Ceunohot and Leumomate. The focal mechanism from seismicity analysis figured the fault orientation from the Seulimeum segment in the direction of NW-SE, which is essential to assess an active fault. Based on data processing, we concluded the the Gravity Model Plus data is effective for first mapping the fault structure in developing countries, such as Indonesia.
ANALYSIS OF FINANCIAL PERFORMANCE USING LIQUIDITY RATIO, SOLVENCY RATIO, ACTIVITY RATIO, PROFITABILITY RATIO IN PHARMACEUTICAL SUB-SECTOR MANUFACTURING COMPANIES ON THE INDONESIA STOCK EXCHANGE FOR THE 2018-2020 PERIOD IN DKI JAKARTA
Authors: Noviyana Syntha , Sherlita Angelia
Published: August 2023

Financial performance is the result or achievement that has been achieved by the company's management in carrying out its function of managing company assets effectively during a certain period. Financial performance is very much needed by companies to find out and evaluate the level of success of the company based on the financial activities that have been carried out. Indonesian Securities for the period 2018-2020. In this study, the types of data used were qualitative and quantitative data with secondary data sources. The data collection procedure in this study is to analyze the financial statements that have been documented using a descriptive and comparative qualitative approach. Based on the results of this study, PT Darya Varia Laboratoria Tbk, PT Kalbe Farma Tbk, PT Kimia Farma Tbk, PT Merck Tbk and PT Pyridam Farma Tbk have had good financial performance at certain financial ratios. The company also has poor financial performance on profitability ratios.
An Overview of The Various Appropriate Types of Cell Lines for The Production of Monoclonal Antibodies
Authors: Javanmard Shahin
Published: August 2023

As the first monoclonal antibodies [mAbs] were produced in 1975, the challenge to improve antibody engineering started. Since then, therapeutic antibodies have become the predominant class of new drugs developed recently, and an essential part of progress has affected cell lines. From the first pioneer hybridoma cells to the current vanguard Chinese hamster ovary [CHO] cells dramatic improvement has been seen. An essential part of this process is choosing the suitable cell line to seed the targeted antibody gene. This review encompasses all the current evidence to compare various proper cell lines for monoclonal antibody production such as mammalian cells, plant cells, bacterial cells, and yeast cells. Valid long-term data, regarding glycosylation, efficiency, and safety, support the current popularity of CHO cells. At the same time, other types of cell lines also show some promise for emerging needs for more therapeutic antibodies on the market.
Antidiabetic and Antioxidant Effects of Bryonia multiflora Boiss. & Heldr. in a Rat Model of Streptozotocin-Induced Diabetes
Authors: Alkan Elif Ebru , Çelik İsmail , Bati Bedia
Published: August 2023

Objective: This aim of this study is to investigate the antidiabetic, antioxidant and hypolipidemic potential of Bryonia multiflora Boiss. & Heldr. in streptozotocin (STZ) induced diabetes in rats. Material and Methods: During 21 days, control group (NC) and diabetes control (DC) were fed only with food and water, while diabetes acarbose group (DAC) was fed with 20 mg / kg of acarbose. The DB1, DB2, DB3 groups were fed with 100 mg / kg, 200 mg/kg and 400 mg / kg Bryonia multiflora plant extract, respectively. The body weight and biochemical parameters glucose level, insulin level, glycosylated hemoglobin, total cholesterol, triglyceride, aminotransferase (ALT), lactate dehydrogenase (LDH), C-peptide, LDL- cholesterol (LDL-c), HDL-cholesterol (HDL-c), creatinine (CRE), blood urea nitrogen (BUN), urea (Ure) and antioxidant parameters were examined for all treated groups and compared against diabetic control group and normal control group. Results: Bryonia multiflora (BM) plant extract (100 mg/kg, 200 mg/kg and 400 mg/kg) that administered in respective groups of diabetic animals for 21 days significantly reduced the blood glucose level and glycosylated hemoglobin ( HbA1c) levels in streptozotocin induced diabetic rats. While the levels of insulin and C-peptide of DC group were found significantly lower (p
SOIL CONDITIONS AND EFFECT OF FERTILIZATION ON THE EMISSION OF GREENHOUSE GASES IN AN ANDEAN COFFEE GRADIENT
Authors: Burneo-Valdivieso Juan , Capa-Mora Daniel , Ochoa-Cueva Pablo
Published: August 2023

Coffee (Coffea arabica and C. canephora) is an important agricultural export product in Ecuador, but yields reported at most coffee farms are low. The main reasons for this are a lack of understanding of soil nutritional status and fertilization management, which implies fertilizer misuse and results in gas emissions into the environment. In this study, the soil nutritional status of coffee plantations was evaluated along an altitudinal gradient of the Ecuadorian Andes as an indicator of soil fertilization plans. A total of 471 farmlands were selected and their pH, soil organic matter, and main macronutrients were determined. The impact of soil fertilization on nitrous oxide emissions was evaluated; for this purpose, an experimental coffee farm was chosen where different doses of mineral and organic soil fertilization were tested, and N2O emissions were determined. The results showed a negative correlation between soil organic matter, pH, and nitrate concentration with altitude. In all altitudinal strata, the nitrate concentration was higher than that of ammonium. In addition, a strong correlation was observed between soil organic matter and soil nitrate concentration. The amount of potassium decreased as altitude increased, whereas medium and high concentrations of available phosphorus were observed in all altitudinal ranges. However, significant statistical differences were found when comparing low mineral fertilization doses to organic fertilization. The N2O analyses showed that coffee plantations fertilized with mineral fertilizers emit from 300 to 1142 mg N2O m-2 into the environment. High mineral fertilization resulted in the highest N2O emissions, with statistically significant differences when compared to low mineral doses and organic fertilization. Therefore, it was concluded that changes in soil nutritional status were observed along the Andean gradient of coffee plantations in southern Ecuador, and that high doses of mineral fertilizer can have a significant impact on N2O emissions.
ANALYSIS OF USER COMMUNITY SATISFACTION KAMPUNG RAMBUTAN TERMINAL
Authors:   Department of Civil Engineering, Universitas Mercu Buana, Jakarta, Indonesia, Firdaus Hendy Yusman , Isradi Muhammad ,   Department of Civil Engineering, Universitas Mercu Buana, Jakarta, Indonesia, Prasetijo Joewono ,   Faculty of Engineering Technology, Universiti Tun Hussein Onn Malaysia, Malaysia, Kinasih Reni Karno ,   Department of Civil Engineering, Universitas Mercu Buana, Jakarta, Indonesia, Hasdian Elhazri ,   Department of Civil Engineering, Universitas Mercu Buana, Jakarta, Indonesia, Andraiko Heru ,   Department of Civil Engineering, Universitas Mercu Buana, Jakarta, Indonesia
Published: August 2023

The terminal is a manifestation of a road transportation node that serves the community as a transportation location, such as intra- and intermodal locations for passengers and loading and unloading of goods, as well as regulating the smooth flow of arrivals and departures of public vehicles. The purpose of this study is to determine the level of satisfaction and the level of service performance using objective measures to highlight changes that should be made to the Kampung Rambutan terminal service. The method used is to calculate based on the results of a questionnaire based on the standardization of PM No. 40 of 2015 and then process the results using the Customer Satisfaction Index (CSI) method to determine the public's perspective on services at the Kampung Rambutan terminal and Importance Performance Analysis (IPA) to map attributes that require priority improvement at the Kampung Rambutan terminal. The results of the analysis through CSI obtained a satisfaction index of 54.40%, meaning that service users are quite satisfied with the services provided. Meanwhile, IPA obtained 10 service attributes that require priority improvement. There are several important aspects that should be considered, such as environmental cleanliness, facilities for users with disabilities.
Financial Feasibility Study in the Construction of the “Katering Nusantara” Project in the New National Capital of Indonesia (IKN) PT. XYZ
Authors:   School of Business Management, Institut Teknologi Bandung, Sutejo Daffa Adiyatama , Rahadi Raden Aswin ,   School of Business Management, Institut Teknologi Bandung
Published: August 2023

The development of an Indonesia new national capital requires a significant workforce, with over 260,000 construction workers needed for the phase 1 construction between 2022 and 2024. To support this massive undertaking, PT. XYZ received an opportunity to provide catering services for 4,500 employees involved in building the nation’s capital, known as Katering Nusantara. Recognizing the potential of the catering industry as a stimulant for corporate growth, PT. XYZ expanded its product line, from only focusing on inflight catering to remote industrial catering. While the inflight catering business relies on flight availability and aviation infrastructure, the industrial catering segment offers more flexibility and opportunities for growth through participating in tenders at various factories across Indonesia. As part of the study, a financial feasibility analysis will be conducted to evaluate the investment in Katering Nusantara, considering factors such as investment costs and overall feasibility. Financial feasibility study conducted in this project to allow PT.XYZ assess the potential risk and return associated with the Katering Nusantara project. The investment of Katering Nusantara will cost Rp5,275,990,000 and will be funded using debt and equity. In the research reveal that the payback period 3.82 years, with a Net Present Value (NPV) of Rp. 11,647,468,485, a profitability index 2.21, and Internal Rate of Return (IRR) of 45%, which surpasses cost of capital 14.38%. This suggests that PT.XYZ should proceed with the implementation of the Katering Nusantara project. At the same time, it is important to note that the project’s financial performance is sensitive to changes in catering sales prices, emphasizing the need for cost optimization and alternative pricing strategies to mitigate potential fluctuations.
The Politics of Language Policy in Relation with Identity Issue in Contemporary Africa: Case of Tunisia
Authors:   Istanbul Ticaret University, Bettaher Oumayma
Published: August 2023

This Article outlines the politics of language policies in Tunisia in relation with the issue of Tunisian identity. The Tunisian society is a multilingual one par excellence, since pre-colonialism and due to its strategic location, Tunisia witnessed several linguistic changes. This paper focuses on the policies implemented by policymakers which can be divided into three main movements: Arabization, the preservation of French and the promotion for English. Since Tunisia gain its independence in 1956, the strong presence and implementation of French language threatened the flow of the Arabization movement. With the appearance of globalization, Policy makers tried to balance between the already existed languages with English due to its importance in today’s world. This paper argues that such policies, especially in the educational system, had a direct impact on the post-colonial identity.
Playful strategies for effective high school biology teaching
Authors: Pinargote Jimenez Juana D. , Oviedo Mirna C.
Published: August 2023

This paper presents an educational design that develops, implements, and evaluates certain educational games to support teaching and learning biology in secondary school. A quasi-experimental design was employed in which biology was taught to an experimental group using educational games while a control group was taught using traditional methods. The quasi-experiment was conducted in the first year of a technical high school, with two biology teachers assigned to each of the groups involved in the study. Both the control group and the experimental group consisted of 40 students. The study used observation guides, surveys, and questionnaires to collect data. The results demonstrate that educational games positively impact the teaching and learning of biology.
Novel β-lactamase inhibitors and the pursuit of MBL inhibitors to combat antibiotic-resistant bacteria: a review
Authors: A. Saleh Ahmed , A. J. Mahmood Ahmed
Published: August 2023

Bacterial resistance is spreading internationally and poses a serious threat to humans. β-lactam resistance has enhanced to an uncontrolled rate due to many reasons. The most significant form of resistance is destruction of the ß-lactam ring by a bacterial enzyme named ß-lactamase enzyme which is essential for antibacterial activity. There are currently six β-lactamases inhibitors that can be used clinically in conjugation with the antibiotic in order to protect them from enzymatic attacks. They bind the β-lactamase enzyme thus the β-lactam antibiotic catches the transpeptidase (PBP) which has the responsibility of peptidoglycan synthesis and disables it thus causing cell wall lysis. However, in order to tackle the fast escalating ß-lactam resistance, additional research is needed in order to create novel drugs with broad-spectrum. Herein we represent the recently published works of the β-lactamases inhibitors. Until nowadays there are no clinically approved MBL inhibitors, Efforts should be put to discover and evaluate novel MBLi to impede the spread of pathogenic-resistant bacteria and minimize their global health impact. The scientists realize this fact and emphasize their effort toward MBL inhibitors.
Prevalence of Antisocial Behavior among Secondary School Students in Nairobi City County
Authors: Ndehi Violet , Ndung’u Elijah , Nyagah Virginia
Published: August 2023

Purpose: The aim of this study was to determine how common antisocial behavior is among secondary school students in Nairobi City County. 

Methodology: The study employed a parallel convergent mixed-method design with a target population of 38,641 adolescents, parents, and teachers in Nairobi County secondary schools. Quantitative Data was collected from 398 adolescents in forms 2 and 3 via random sampling. All school categories were represented through cling cluster sampling, while simple random sampling selected respondents within each school. Qualitative data was purposively obtained from 10 students, 10 parents, and 10 teachers. Proven psychometric tools like Assessment of identity Development in Adolescence, Strengths and Difficulties Questionnaire, Children’s Perception of Inter-Parental Conflict Scale, and Dhaka Stress Scale-Adolescent collected quantitative data. Pearson coefficient correlations were calculated using Statistical Package for Social Sciences (SPSS version 25) to explore relationships between variables.

Findings: Based on this analysis, this study revealed the prevalence of moderate to severe antisocial behaviour in at least half of the adolescents in Nairobi. This is, however, not unique to the county. In attempting to explain the causes of antisocial behaviour among adolescents using the Problem Behaviour Theory by Jessor, et al. (2004), many scholars have witnessed it as a worldwide phenomenon.

Unique Contribution to Theory, Practice and Policy: The study recommended for the involvement of counselling professionals in the screening and treatment. The Ministry of Education must also undertake the task of harmonizing the school curriculum. By doing so, the curriculum can be developed into a well-balanced and comprehensive framework that promotes a healthier learning environment for students.
Emmanuel González Alvarado
Authors: Rodríguez Brenes Kattia
Published: August 2023

“Sin pasión ni amor, no se construye ni se logra nada, y por esto los seres humanos nos entendemos en el amor” frase del Rector Emmanuel González Alvarado.

Una encantadora expresión que inicia la Historia de vida de esta primera edición del año 2023 de la Revista Académica Divulgativa Arjé, la que nos enorgullece contar, puesto que nos permite reconocer desde una visión más personal, familiar y académica a nuestro protagonista. En esta ocasión, conoceremos anécdotas que nosotros desconocemos de Don Emma…” como le dicen algunos”, lo anterior, nos permite valorar esa huella personal de entrega y entereza por el trabajo y por su pasión: el cuido del ambiente. Para comprender mejor el significativo vínculo de Don Emmanuel con la educación, en especial, con la formación técnica y con los procesos educativos con sentido vital, parafraseamos al autor Maturana, quien expresa que el conocimiento no debe ser entregado de forma mecánica, sino que tiene ser construido a partir de la experiencia y la interacción con el entorno naturalmente biológico. Además, don Emmanuel se declara un apasionado del cuido del ambiente, asimismo, un agente de cambio con gran compromiso social, asociado con la protección del planeta y con la formación de personas conscientes y críticas, que sean capaces de cuestionar y reflexionar sobre el mundo que los rodea, por lo que él pregona que “La educación y la naturaleza están estrechamente relacionadas, y ese contacto vivo y directo con la naturaleza, es esencial para la educación”. Lo anterior, porque está convencido que ambas generan cambios significativos en los individuos, mediante un desarrollo sostenible y armonioso con la naturaleza.
YEW EXTRACTS - A POSSIBLE SOURCE OF BIOACTIVE COMPOUNDS WITH POTENTIAL ALLELOPATHIC PROPERTIES
Authors: Frunzete Madalina - Elena , Rodideal Tatiana , Zamfirache Maria – Magdalena
Published: August 2023

Representative species of the Taxus genus, known since antiquity for their toxicity, have been an essential plant resource for the production of plant extracts with medicinal properties (anti-inflammatory, antifungal, and antibacterial) and, more recently, for the study of their allelopathic properties with significant implications in organic agriculture (bioherbicidal potential). With a view to the development of this new direction of research, the present work aims: to present a qualitative evaluation of two types of plant extracts (aqueous and alcoholic) of different concentrations (1% and 5%) obtained from various organs (bark, leaves, arils, and seeds) belonging to three Taxus taxa: a spontaneous taxa - Taxus baccata L. (T1) and two cultivated taxa - Taxus baccata (T2) and Taxus baccata 'Robusta' (T3) at different times of the phenological cycle by determining their absorption spectra (of both types of extracts), total amounts of polyphenols and flavonoids, and by evaluating their antioxidant capacity (alcoholic extracts); to investigate, under experimental conditions of cultivation the possible allelopathic effects induced by the aqueous extracts on the germination and development of the seedlings in two test plant species: Amaranthus retroflexus L. (ruderal species) and Lycopersicon esculentum Mill, variety Silvia (crop species). The data indicates the presence of phenolic and compounds, alkaloids, and carotenoid pigments in the alcoholic extracts prepared from the different organs of the studied yew taxa, showing higher amounts of polyphenols and flavonoids in the extracts obtained from the leaves of taxon T2 compared to taxon T1. The effect of 1% and 5% aqueous extracts obtained from the bark of the three investigated yew taxa, as well as 1% aqueous extracts prepared from the leaves of taxon T3 on seed germination and seedling growth was more pronounced in the crop species Lycopersicon esculentum Mill, variety Silvia, compared to the ruderal broadleaf weed Amaranthus retroflexus L., both species having rapid germination stimulated by ambient light. Aqueous extracts of 5% concentration obtained from the arils of plants belonging to the three yew taxa stimulated the elongation of the seedlings’ hypocotyls of both test species.