bluuebunny/crossref_metadata_2025 huggingface dataset:
Double-Sided Metasurfaces for Dual-Band Mid-Wave and Long-Wave Infrared Reflectors
Authors: Ko Yeong Hwan , Magnusson Robert
Published: December 2024

We present an innovative method for dual-band mid-wave infrared (MWIR) and long-wave infrared (LWIR) reflectors. By using double-sided metasurfaces, two high reflection bands can be generated with a single device. As individual guided-mode resonance (GMR) reflectors are combined with interlayer (or substrate) on the top and bottom sides, we achieved high reflection in the MWIR and LWIR bands simultaneously. Each GMR reflector was optimized as a germanium (Ge) grating structure on a potassium bromide (KBr) substrate. In our analysis, it was found that the transparency of the interlayer is critical to produce the dual-band reflection. The simulation results on the Ge/KBr/Ge double-sided metasurfaces demonstrated wideband reflection from ~3.3 to 4.8 μm and ~8.8 to 11 μm. Additionally, the device exhibited favorable angular tolerance. The work contributes to developing capability of metasurface technologies in various application fields.
Exploring the Modelling of Gold Anisotropic Nanoparticles’ Optical Properties as a Promising Tool for Detection Systems Design
Authors: Sifuentes Jorge , Galarreta Betty Cristina , Hernandez Yulan
Published: December 2024

Gold nanoparticles have been a central topic in the last few decades due to their excellent optical properties that can be exploited in many applications, including food analysis, materials science, and biomedicine. The basis of these unique optical properties is the phenomenon known as localized surface plasmon (LSP), which relays in the collective oscillation of the conduction band electrons in the nanoparticle when excited by electromagnetic radiation. The optical properties of the nanoparticles are critical for selecting the best nanomaterials for each application, a key factor for optimum performance, and can be tuned due to their dependence on the geometry and size of the nanoparticles, as well as the polarization of the light beam. Here, we conducted simulations to study the tunable optical properties and local electric field distribution of three types of gold nanoparticles, cubes (AuNC), boxes (AuNB), and triangular prisms (AuNT), which have relatively simple synthetic routes. Finally, we compared these results with experimental data and described possible synthetic routes to discuss the positive and negative aspects of using each type of nanoparticle for potential applications.
A Genome-Wide Characterization of Receptor-like Cytoplasmic Kinase IV Subfamily Members in Populus deltoides Identifies the Potential Role of PdeCRCK6 in Plant Osmotic Stress Responses
Authors: Pan Huanhuan , He Zhengquan , Liu Linxiu , Cai Renyue , Huang Hu , Xie Xinru , Cao Xun , Li Yanan , Qiu Wenmin , Lu Zhuchou , Han Xiaojiao , Qiao Guirong , Zhuo Renying , Hu Jianjun , Xu Jing
Published: December 2024

The IV subfamily of receptor-like cytoplasmic kinase (RLCK-IV), known as calcium-binding receptor-like cytoplasmic kinases (CRCKs), plays a vital role in plant signal transduction, particularly in coordinating growth and responses to abiotic stresses. However, our comprehension of CRCK genes in Populus deltoides, a species characterized as fast-growing and pest-resistant but with drought intolerance, is limited. Here, we identify 6 members of the CRCK subfamily on a genome-wide scale in P. deltoides, denoted as PdeCRCK1–PdeCRCK6. An evolutionary and structural analysis revealed highly conserved kinase catalytic domains across all PdeCRCKs, characterized by calmodulin (CaM)-binding sites and serine (Ser)/threonine (Thr) phosphorylation sites. The cis-acting elements of promoters indicated the presence of responsive elements for plant hormones, abiotic stresses, and transcription factor binding sites, which is supported by the distinct transcriptional expression patterns of PdeCRCKs under abscisic acid (ABA), polyethylene glycol (PEG), and mannitol treatments. A transient overexpression of PdeCRCK3/5/6 in tobacco (Nicotiana benthamiana) leaves indicated their involvement in reactive oxygen species (ROS) scavenging, polyamine gene synthesis, and ABA signaling pathway modulation. Immunoprecipitation–Mass Spectrometry (IP–MS) and a yeast two-hybrid (Y2H) assay showed that PdeCRCK6 interacted with AAA-type ATPase proteins and ubiquitin, suggesting its potential function in being involved in chloroplast homeostasis and the 26S ubiquitin protease system. Taken together, these findings offer a comprehensive analysis of the RLCK-IV subfamily members in P. deltoides, especially laying a foundation for revealing the potential mechanism of PdeCRCK6 in response to osmotic stresses and accelerating the molecular design breeding of drought tolerance in poplar.
Genome-Wide Identification, Classification, Expression Analysis, and Screening of Drought and Heat Resistance-Related Candidates of the Rboh Gene Family in Wheat
Authors: Cao Miyuan , Zhang Yue , Zou Xiaoxiao , Yin Huangping , Yin Yan , Li Zeqi , Xiao Wenjun , Liu Shucan , Li Yongliang , Guo Xinhong
Published: December 2024

Plant respiratory burst oxidase homologs (Rbohs) are key enzymes that produce reactive oxygen species (ROS), which serve as signaling molecules regulating plant growth and stress responses. In this study, 39 TaRboh genes (TaRboh01–TaRboh39) were identified. These genes were distributed unevenly among the wheat genome’s fourteen chromosomes, with the exception of homoeologous group 2 and 7 and chromosomes 4A, as well as one unidentified linkage group (Un). TaRbohs were classified into ten distinct clades, each sharing similar motif compositions and gene structures. The promoter regions of TaRbohs contained cis-elements related to hormones, growth and development, and stresses. Furthermore, five TaRboh genes (TaRboh26, TaRboh27, TaRboh31, TaRboh32, and TaRboh34) exhibited strong evolutionary conservation. Additionally, a Ka/Ks analysis confirmed that purifying selection was the predominant force driving the evolution of these genes. Expression profiling and qPCR results further indicated differential expression patterns of TaRboh genes between heat and drought stresses. TaRboh11, TaRboh20, TaRboh22, TaRboh24, TaRboh29, and TaRboh34 were significantly upregulated under multiple stress conditions, whereas TaRboh30 was only elevated in response to drought stress. Collectively, our findings provide a systematic analysis of the wheat Rboh gene family and establish a theoretical framework for our future research on the role of Rboh genes in response to heat and drought stress.
Kick Risk Diagnosis Method Based on Ensemble Learning Models
Authors: Wu Liwei , Zhou Detao , Li Gensheng , Gong Ning , Song Xianzhi , Zhang Qilong , Yan Zhi , Pan Tao , Zhang Ziyue
Published: December 2024

As oil and gas exploration and development gradually advance into deeper and offshore fields, the geological environment and formation pressure conditions become increasingly complex, leading to a higher risk of drilling incidents such as kicks. Timely diagnosis of kick risk is crucial for ensuring safety and efficiency. This study proposes a kick risk diagnosis method based on ensemble learning models, which integrates various time-series analysis algorithms to construct and optimize multiple kick diagnosis models, accurately fitting the relationship between integrated logging parameters and kick events. By incorporating high-performance ensemble models such as Stacking and Bagging, the accuracy and F1 score of the models were significantly improved. Furthermore, the application of the Synthetic Minority Over-sampling Technique and Tomek Links (SMOTE-Tomek) data balancing technique effectively addressed the issue of data imbalance, contributing to a more robust and balanced model performance. The results demonstrate that integrating time-series analysis with ensemble learning methods significantly enhances the predictive reliability and stability of kick monitoring models. This approach provides a dependable solution for addressing complex kick monitoring tasks in offshore and deepwater drilling operations, ensuring greater safety and efficiency. The findings offer valuable insights that can guide future research and practical implementation in kick risk diagnosis.
Study on Explosion Venting Characteristics of L-Type Venting Duct
Authors: Wu Fan , Zhou Xing , Hao Yongmei , Zhuang Sunqi
Published: December 2024

The failure state of the natural gas pipelines in underground space may cause explosions, and an explosion flow field is affected by the structure of the venting duct. Based on FLACS software v9.0, the influence of the explosion vent and venting duct on temperature and pressure fields is studied. The results show that when the area of the explosion vent increases from 0 to 100 cm2, the peak overpressure decreases by half, and the overpressure drops to zero within 0.3 s. For different L-type venting ducts, when the structural coefficient is less than 5, the peak overpressures and pressure variations are similar. When the structural coefficient is equal to 5, the peak overpressure significantly decreases, and the time to reach the peak value is extended by 50%. From the perspective of achieving a safe and efficient venting effect, the optimal structural coefficient is 5 for the L-type venting duct.
Prediction of Chemical Composition of Gas Combustion Products from Thermal Waste Conversion
Authors: Skrzyniarz Magdalena , Morel Sławomir , Rzącki Jakub
Published: December 2024

The current global energy crisis is driving the need to search for alternative raw materials and fuels that will be able to ensure the continuity of strategic industries, such as the steel industry. A chance to reduce the consumption of traditional fuels (e.g., natural gas) is to utilise the potential of gases from the thermal conversion of waste, and, in particular, pyrolysis gas. Unfortunately, despite its high calorific value, this gas is not always suitable for direct, energy-related use. The limitation is the type of waste subjected to pyrolysis, particularly plastics, rubber and textiles. Due to the above, this article proposes the co-combustion of pyrolysis gas in a ratio of 1:10 with natural gas in a pusher reheating furnace employed to heat the charge before forming. The chemical composition of flue gases generated during the combustion of natural gas alone and co-combustion with pyrolysis gas from various wastes was modelled, namely, two types of refuse-derived fuel (RDF) waste, a mixture of pine chips with polypropylene and a mixture of alder chips with polypropylene. The calculations were performed using Ansys Chemkin-Pro software (ver. 2021 R1). The performed computer simulations showed that the addition of pyrolysis gas for most of the analysed variants did not significantly affect the chemical composition of the flue gases. For the gases from the pyrolysis of biomass waste with the addition of polypropylene (PP), higher concentrations of CO and H2 and unburned hydrocarbons were observed than for the other mixtures. The reason for the observed differences was explained by conducting a formation path analysis and a sensitivity analysis for the selected combustion products.
Optimization of Extraction Process for Improving Polyphenols and Antioxidant Activity from Papaya Seeds (Carica papaya L.) Using Response Surface Methodology
Authors: Robles-Apodaca Silvia Mitzel , González-Vega Ricardo Iván , Ruíz-Cruz Saúl , Estrada-Alvarado María Isabel , Cira-Chávez Luis A. , Márquez-Ríos Enrique , Del-Toro-Sánchez Carmen Lizette , Ornelas-Paz José de Jesús , Suárez-Jiménez Guadalupe M. , Ocaño-Higuera Víctor Manuel
Published: December 2024

Papaya seeds (Carica papaya L.), a by-product of the food industry, contain primary metabolites and offer secondary health benefits, but are often considered a waste with no value. Therefore, the aim of this research was to optimize the extraction process of polyphenols from papaya seeds (Carica papaya L.) to maximize their antioxidant activity using the response surface methodology (RSM). A design of experiment (DOE) approach was applied to produce the optimum conditions of factors such as solvent concentration (0–100%), temperature (30–60 °C), time (1–6 h), and exhaustion (1–6 times) to improve the extraction process. The response variables were the number of phenols and flavonoids, and the inhibition capacity of the DPPH and ABTS radicals. The main findings indicated that optimal conditions—100% solvent concentration, a temperature of 30 °C, an extraction time of 6 h, and 6 depletion cycles—maximized the yield of total polyphenols, total flavonoids, and antioxidant capacity, as evaluated using ABTS and DPPH assays. The extracts presented values of 2.521 to 6.168 mg AGE/g DW for total polyphenols and 30.830 to 68.599 mg QE/g DW for total flavonoids. Likewise, they presented an antioxidant capacity using DPPH and ABTS methods with values of around 15.151 to 72.389 and 29.434 to 165.393 μM TE/g DW, respectively. Identification was also performed using liquid chromatography to determine the presence of sugars (glucose, fructose, and sucrose) and organic acids (oxalic, citric, tartaric, malic, quinic, and succinic). However, optimal values were presented outside the study area, which indicates the maximum point of the surface was at intervals higher than those studied in this investigation. The papaya seed can be applied in future research for the optimization of bioactive compounds extracted from vegetable waste and it represents a matrix with potential in the area of technological development and health.
Contemporary and Future Secondary Copper Reserves of Southeast Asian Countries
Authors: Le Thi Van , Dente Sebastien Michael Rene , Hashimoto Seiji
Published: December 2024

This study employed dynamic material flow analysis (MFA) and mass balance principles to examine copper flows in Indonesia, Malaysia, the Philippines, Thailand, and Vietnam from 1960 to 2020, with projections extending to 2050 using five shared socioeconomic pathway (SSP) scenarios. We applied the secondary resources classification framework to assess secondary copper resources and their recoverability in these countries. The results indicated that total copper stocks across these countries would continue to rise, with Indonesia’s copper stock projected to reach around 5000–12,000 kt by 2050, the highest among the five nations. In 2022, Malaysia had the highest per capita copper stock at 100 kg/person, although all countries were expected to remain below the per capita stock levels seen in major copper-consuming developed countries by 2050. Copper demand was projected to increase by 118–238 kt annually from 2023 to 2050, leading to a significant rise in end-of-life copper scrap. By 2050, secondary copper reserves in Indonesia were estimated to reach 4096 kt, with similar growth trends observed in other countries (3898 kt in Thailand, 3290 kt in Vietnam, 3096 kt in Malaysia, and 2564 kt in the Philippines). This highlights both the potential for resource recovery and the need for improved waste management. If recycling rates increase to 80–90%, secondary reserves could meet up to 42–65% of the copper demand in 2050. However, current recycling rates remain well below this potential, underscoring the urgent need for better waste management systems. This study emphasizes the balance between economic development and resource sustainability, offering critical insights for policymakers to improve recycling efficiency and reduce reliance on primary copper sources.
Physical Activity and Sedentary Behavior on Well-Being and Self-Rated Health of Italian Public Health Medical Residents During the COVID-19 Pandemic: The PHRASI Study
Authors: Catalini Alessandro , Minutolo Giuseppa , Caminiti Marta , Ancona Angela , Cosma Claudia , Gallinoro Veronica , Gianfredi Vincenza
Published: December 2024

High workloads and extended work shift greatly limit the opportunities for medical residents to adopt a healthy lifestyle by practicing regular physical exercise. Using data from the Public Health Residents’ Anonymous Survey in Italy (PHRASI), this research assessed the associations between physical activity levels and sedentary behavior, well-being, and self-rated health among Italian public health residents (PHRs) during the COVID-19 pandemic. Employing a cross-sectional design, this study utilized the International Physical Activity Questionnaire, the WHO-5 Well-being Index, and the single-item self-rated health to measure physical activity, sedentary behavior, self-rated health, and well-being among PHRs. The study included 379 PHRs. Multiple logistic regressions adjusted for age and sex were applied to explore the associations among the variables of interest. While 74% of PHRs were sufficiently active, 50% reported good well-being. We found a positive association between physical activity (specifically walking and intense activities) and well-being (aOR 1.292, p = 0.032). At the same time, sedentary behavior was negatively associated with self-rated health (aOR 0.948, p = 0.022) and well-being (aOR 0.945, p = 0.005). This study contributes valuable insights into the role of physical activity and sedentary behavior in PHRs’ mental health, calling for targeted public health strategies to support their well-being.
Framework for Enhancing Urban Living Through Sustainable Plant Selection in Residential Green Spaces
Authors: Priya Udayasoorian Kaaviya , Senthil Ramalingam
Published: December 2024

Residential greening is a critical strategy for mitigating the negative impacts of urbanization on the environment, biodiversity, and human well-being. Proper plant species selection is essential for the success of residential greening projects, as it influences the ecological, aesthetic, and health outcomes. This review provides a comprehensive framework for selecting plant species for residential greening, considering environmental suitability, aesthetic values, maintenance requirements, and potential health effects. The plant’s adaptability to local climatic conditions, soil type, and water availability are key considerations. Aesthetic factors like plant form, texture, color, and seasonal interest should be balanced with maintenance needs, including pruning, fertilization, and pest control. Potential health concerns, like allergenic pollen or toxic properties, must also be evaluated while deploying residential greeneries. The guide emphasizes the importance of selecting native or well-adapted non-invasive species to support local biodiversity and minimize ecological disruption. Employing a systematic approach to plant selection for urban vegetation and residential greening initiatives can enhance the environmental, social, and health benefits. Plant species invasiveness is a critical global concern, with substantial ecological, economic, and social impacts that demand careful consideration in species selection and management. This method maximizes these advantages and promotes long-term sustainability and resilience against the challenges posed by climate change. This present review supports the UN’s Sustainable Development Goal 11: Sustainable Cities and Society.
Protective Efficacy of an Inactivated Recombinant Serotype 4 Fowl Adenovirus Against Duck Adenovirus 3 in Muscovy Duck
Authors: Lin Yun , Jiang Wenjie , Ma Lihua , Zhang Jiayu , Tang Ye , Kan Qiuqi , Xiong Haifeng , Wu Jiayan , Zhang Jun , Niu Yiwen , Zhang Wei , Wang Shengnan , Wang Weikang , Xie Quan , Li Tuofan , Wan Zhimin , Gao Wei , Shao Hongxia , Qin Aijian , Ye Jianqiang
Published: December 2024

Background: Duck adenovirus 3 (DAdV-3) is an emerging pathogen that has caused severe economic losses to the duck industry in China. Recently, the infection of ducks with serotype 4 fowl adenovirus (FAdV-4) has also been reported in China. Therefore, an efficient bivalent vaccine to control the diseases caused by DAdV-3 and FAdV-4 is extremely urgent. In our previous study, a recombinant FAdV-4 expressing Fiber-2 of DAdV-3 was generated and designated as rFAdV-4-Fiber-2/DAdV-3. Methods: Here, the recombinant virus rFAdV-4-Fiber-2/DAdV-3 was inactivated to serve as a bivalent vaccine, and its immunogenicity and protective efficacy against DAdV-3 were evaluated in Muscovy ducks. Results: The subcutaneous injection of rFAdV-4-Fiber-2/DAdV-3 could efficiently induce antibodies against Fiber-2 of DAdV-3 and neutralize antibodies against FAdV-4. After challenges with DAdV-3, in comparison with the non-immunized ducks, the immunized ducks did not show any bodyweight loss, gross lesions, or histopathologic change. Moreover, viral loads in livers and kidneys from immunized ducks were undetectable, whereas those in non-immunized ducks with challenge were significantly high. Conclusions: All these data demonstrate that the inactivated recombinant virus rFAdV-4-Fiber-2/DAdV-3 has the potential to be an efficient vaccine candidate against both FAdV-4 and DAdV-3, although efficacy for FAdV-4 needs to be confirmed experimentally.
Longitudinal Immunological Analysis of Portuguese Healthcare Workers Across the COVID-19 Pandemic Reveals Differences in the Humoral Immune Response to Vaccines
Authors: Vilela Luísa , Silva Anabela , Cruz Alberta , Sousa Madalena , Costa Margarida , Fonseca Fernando , Campino Susana , Clark Taane G. , Miranda Anabela
Published: December 2024

Background: A vaccination programme against severe acute respiratory syndrome coronavirus 2 was initiated in Portugal in December 2020. In this study, we report the findings of a prospective cohort study implemented with the objective of monitoring antibody production in response to COVID-19 vaccination. Methods: The humoral immune response to vaccination was followed up using blood samples collected from 191 healthcare workers. Participants were split into three groups: the Oxford-AstraZeneca (Vaxzevria) vaccine group (n = 68), the Pfizer-BioNTech COVID-19 (Comirnaty) vaccine group (n = 51), and the Post-COVID group (n = 72). The kinetics of anti-spike antibody production were evaluated until 56 days on average after the third dose (booster). Results: We observed that antibody titres peaked approximately one month after full vaccination and declined steadily thereafter. We also found that mRNA vaccination induces higher titres of antibodies than viral vector vaccination, and both generate greater antibody responses than mild or moderate COVID-19. Additionally, whilst the booster for the Oxford-AstraZeneca and Pfizer-BioNTech groups led to antibody levels higher than those at any previous sample collection point, the booster for the Post-COVID group (persons with a history of COVID-19 prior to vaccination) led to antibody levels lower than those attained one month after the second dose. Interpretation: Our results indicate that there are different kinetics of antibody production between individuals who received the Pfizer-BioNtech mRNA vaccine and those who received the Oxford-AstraZeneca vector vaccine, or individuals who had COVID-19 before being vaccinated. Additionally, we observed that exposure to either natural infection or vaccination modulates the response to subsequent vaccination. This is particularly evident after administration of the third dose to the Post-COVID group, where our findings point to a hindrance in vaccine boosting, probably due to unwanted feedback by high titres of pre-existing antibodies.
The modern concept of labor-legal status of sportsmen-athletes
Authors:   Federal State Budgetary Educational Institution of Higher Education, Korzun A.V. ,   State Academic University of Humanities,   (Federal State Budgetary Educational Institution,   GAUGN
Published: December 2024

Motorsport is one of the most dynamic and hazardous forms of professional activity, requiring a special approach to the legal regulation of labor and the social protection of racing drivers. Racing drivers, as professional athletes, face unique working conditions and social risks, including high physical and psychological demands, the risk of injuries, and income instability. The topic of the article becomes more and more relevant in the conditions of commercialization of motorsport and its globalization. In different countries, including the US, UK, Italy,
Germany and Russia, the legal status of road racers remains undefined, leading to differences in their rights and
guarantees. They are often classified as independent contractors, which limits their protection and access to social benefits. The lack of specialized legislation creates legal insecurity and makes it difficult to protect the interests of athletes. Therefore, it is necessary to develop a unified law that will clearly regulate the labor relations of road racers, ensure their safety and guarantees, and adapt to international standards. It is also necessary to train specialized legal personnel who will be able, together with the sports federation, to protect and defend the rights of athletes and teams at the international level.
Thyme oil and argan oil's effects on horse welfare
Authors: Paksoy Yavuzkan , Çelik Güney Melis , Koluman Nazan
Published: December 2024

This study examines the effectiveness of thyme oil and argan oil as potential treatments for leg edema in horses. Swollen legs, often a result of infections, injuries, allergies, and underlying health conditions can significantly affect a horse's mobility and overall health. Traditional treatments may include antibiotics, anti-inflammatories, cold therapy, compression bandaging, and rest, but there is growing interest in natural remedies. For this purpose, argan and thyme oil were applied to 22 horses of various ages and different breeds at different times at Mersin Doğa Horse Farm. As a result of the study, some observations before and after the application of thyme and argan oil are listed. In addition, there was a significant association between oils and side effect from rash, itchiness, temperature increase, drinking too much, excessive urination (p
Contribuições do PIBID na Formação de Professores de Matemática em uma Universidade Pública Goiana
Authors: Da Cunha Maria Francisca , Lima Luciano Feliciano de
Published: December 2024

Este texto aborda a formação de professores de matemática através do Programa Institucional de Bolsa de Iniciação à Docência (PIBID), focando na Educação Matemática Crítica (EMC). Discorremos como o PIBID pode possibilitar práticas educativas que incentivam a reflexão crítica sobre o ensino de matemática, relacionando-o com questões do cotidiano dos alunos. A relevância do estudo reside na necessidade de formar professores capazes de ensinar matemática de maneira crítica e reflexiva, alinhada às demandas sociais contemporâneas. Objetivamos, com este relato, apresentar como o PIBID contribui para a formação docente em matemática, investigando experiências práticas, metodológicas e teóricas. A metodologia adotada é qualitativa, envolvendo as interações entre Pibidianos, professores preceptores e formadores. Espera-se que os resultados demonstrem o impacto positivo do PIBID na formação de professores, evidenciando o desenvolvimento de habilidades críticas e reflexivas essenciais para a prática docente.
Ensino de Ciências e alfabetização científica com Aprendizagem Baseada na Resolução de Problemas
Authors: Ferreira Oliveira Deivison , Da Silva Gomes Mariele , Freitas de Souza Ronilson , Pereira Leal José Fernando
Published: December 2024

O artigo analisa as possíveis contribuições de uma intervenção didática, baseada na Aprendizagem Baseada na Resolução de Problemas (ABRP), focada nos impactos ambientais causados por agrotóxicos na Amazônia paraense, com uma discussão voltada para os indicadores de Alfabetização Científica (AC). A pesquisa segue uma abordagem qualitativa, utilizando um estudo de caso, e emprega como instrumentos de coleta de dados a ficha de monitoramento ABRP e o diário de campo. Os dados foram analisados no contexto dos indicadores de AC. A partir dos registros escritos dos alunos, foram identificados esses indicadores, o que sugere que a intervenção didática contribui de maneira significativa para esse aspecto educacional. Dessa forma, a intervenção esclarece aos alunos os malefícios causados ao meio ambiente pelo uso indiscriminado de agrotóxicos, destacando a importância de utilizá-los de forma correta e responsável, respeitando as normas de segurança.
Desafios e disparidades na saúde oral de crianças autistas: discutindo barreiras e necessidades não atendidas – revisão de literatura
Authors: Tamborini Poliana da Silva , Mendonça Isabelle Thayna de Andrade , Silva Marcílio José Mendonça da , Freitas Juliana Rocha de
Published: December 2024

O Transtorno do Espectro Autista (TEA) é caracterizado por déficits na comunicação social e comportamentos repetitivos que afetam o autocuidado, incluindo a saúde oral. Este estudo teve como objetivo revisar as principais disparidades e desafios no cuidado odontológico de crianças autistas, destacando barreiras comportamentais, sensoriais e no acesso aos serviços de saúde bucal. Para isso, foi realizada uma pesquisa sistemática em bases de dados como PubMed, SciELO, Google Acadêmico e Periódico CAPES, utilizando palavras-chave relacionadas a “saúde oral”, “crianças autistas” e “disparidades no acesso à saúde bucal”. A triagem inicial resultou em 102 artigos, dos quais 10 foram selecionados para análise detalhada com base em critérios de inclusão e exclusão. Os resultados revelaram que crianças autistas apresentam uma prevalência significativamente maior de cáries e doenças periodontais, agravada por barreiras comportamentais, como resistência ao tratamento e sensibilidade sensorial, que frequentemente exigem anestesia geral. A falta de capacitação dos profissionais de saúde bucal e o envolvimento insuficiente das famílias nas práticas de higiene oral também foram identificados como fatores que ampliam as disparidades. As discussões indicam a necessidade de abordagens personalizadas, ambientes clínicos adaptados e maior inclusão familiar para melhorar o cuidado odontológico dessas crianças. Conclui-se que, para reduzir as disparidades no tratamento odontológico de crianças autistas, são necessárias intervenções que adaptem o ambiente clínico e treinem profissionais para lidar com as demandas comportamentais e sensoriais. Além disso, programas educativos para pais e cuidadores são fundamentais para fortalecer o autocuidado e prevenir doenças bucais.
Perfil epidemiológico das internações por Doença de Crohn e colite ulcerativa em crianças e adolescentes entre 2013 e 2023 pelas regiões do Brasil
Authors: Paes Laura Marães , Coelho Gabriel Magalhães , Carmo Yan Vítor Porto do , Steinen Alice Fernandes Von Den , Zamuner Carlos Eduardo Moutinho
Published: December 2024

Introdução: A doença inflamatória intestinal, representada principalmente pela doença de Crohn e colite ulcerativa, se manifesta de forma mais agressiva e extensa quando se inicia na infância ou adolescência. Nos últimos anos, houve aumento da sua incidência na população pediátrica. Cerca de 25% dos pacientes desenvolvem essa doença na infância ou adolescência, no entanto, o diagnóstico nessa faixa etária ocorre em 15 a 20% do total de pacientes. Objetivo: Analisar o perfil epidemiológico do número de internações por Doença de Crohn e colite ulcerativa de crianças e adolescentes nas regiões do Brasil. Método: Trata-se de um estudo epidemiológico, ecológico e descritivo, com dados do Departamento de Informática do Sistema Único de Saúde (DATASUS), na categoria de morbidade hospitalar do SUS pelo CID-10. A amostra foi composta por pacientes de 0 a 19 anos internados por doença de Crohn e colite ulcerativa entre 2013 e 2023. Utilizou-se as variáveis: ano de atendimento, região brasileira, unidade da federação, cor/raça, faixa etária, sexo, média de permanência, custos médios de internação e óbitos.  Os dados foram calculados e analisados por meio do software Microsoft Office Excel. Resultados: As internações hospitalares por Doença de Crohn e Colite Ulcerativa totalizaram 10.816 entre 2013 e 2023, com maior concentração na região Nordeste, que registrou 3.775 internações (34,9%), seguida pela região Sudeste com 3.384 internações (31,29%). A média de permanência hospitalar variou entre 4,5 e 6,7 dias. Durante o período analisado, ocorreram 53 óbitos, sendo a maioria na região Sudeste (37,7%). A maioria dos pacientes se identificou como branca (35,7%) ou parda (30,4%). O custo médio por internação em 2023 foi de R$657,82, com a maior concentração de gastos na região Sudeste (42,97% do total). Discussão: A concentração de hospitalizações nas regiões Sudeste e Nordeste têm associação direta ao desenvolvimento econômico nos últimos 10 anos. Nota-se disparidades regionais relacionadas ao valor médio de internações que reflete desigualdades no sistema de saúde. Além disso, a média de permanência hospitalar sugere o nível de gravidade da doença, assim como o número de óbitos evidencia sua baixa letalidade em pacientes pediátricos no Brasil. Na maioria dos casos, os pacientes são brancos demonstrando acesso desigual à saúde. Conclusão: Evidencia-se disparidades em relação à distribuição do número de internações entre as regiões do Brasil, que podem estar associadas a fatores predisponentes já discutidos. A produção de dados epidemiológicos auxilia na identificação das localidades que necessitam de políticas públicas direcionadas para prevenção de complicações, diagnóstico precoce e tratamento eficaz.
O uso dos novos anticoagulantes orais na fibrilação atrial - revisão de literatura
Authors: Donalonso Rafaela Andrade , Telles Rafaella Castilho da Silva , Neto Geraldo Soares de Lima , Cunha Liana Andreza Dias da , Sousa João Rafael Coelho Cruz e , Gomes Amanda Letícia Rodrigues , Moreira Anadiely , Carvalho Giulia Carolina Pretto
Published: December 2024

A fibrilação atrial (FA) é uma taquiarritmia sustentada de grande importância na prática clínica, afetando 3% da população adulta. Um dos seus pilares terapêuticos é a terapia anticoagulante em pacientes com risco aumentado de fenômenos tromboembólicos. Os novos anticoagulantes orais (NOACs) vêm ganhando espaço no tratamento de pacientes com FA de origem não valvar. Foi realizada uma revisão de literatura a fim de comparar a eficácia, riscos e benefícios dos NOACs em relação à varfarina em pacientes com FA. Concluiu-se que os NOACs representam um avanço na profilaxia de acidente vascular cerebral (AVC) no grupo de pacientes com FA de origem não valvar, principalmente por apresentarem melhor perfil de segurança em relação a eventos hemorrágicos a longo prazo, pela não necessidade de monitoramento da anticoagulação.
Desenvolvimento e avaliação do potencial nutracêutico de uma farinha alimentícia a partir do uxi amarelo (Endopleura uchi)
Authors: Caetano Emanuele Sousa da Silva Caetano , Fernandes Larissa Cristine Pinheiro , Dias Natalice Pedroso , Ramos Ândrea Carolina de Azevedo , Fernandes Joice Farias , Silva Odilene Lima da , Júnior Antônio Quaresma da Silva
Published: December 2024

Endopleura uchi, conhecida como uxi amarelo, é uma fruta nativa da Amazônia com propriedades nutricionais promissoras, mas pouco exploradas. Estudos anteriores indicam que a polpa do uxi possui nutrientes essenciais, como vitaminas, minerais e antioxidantes, que podem beneficiar a saúde humana e promover o desenvolvimento de novos produtos funcionais para a indústria alimentícia, especialmente voltados para dietas sem glúten. O presente estudo teve como objetivo desenvolver uma farinha alimentícia a partir do uxi amarelo e avaliar seu potencial nutracêutico por meio da caracterização físico-química, análise da atividade antioxidante e antibacteriana. Os frutos foram coletados, higienizados, despolpados, desidratados a 80°C e triturados para obtenção da farinha. Foram realizadas análises de umidades, cinzas, proteínas e lipídios; seguindo as normas do Instituto Adolfo Lutz, além da determinação do índice de acidez e pH. A atividade antioxidante foi medida pelo método DPPH, e a atividade antimicrobiana foi avaliada pelo método de disco-difusão com bactérias Escherichia coli, Staphylococcus aureus e Enterococcus faecalis. Os resultados da análise centesimal indicaram que a transformação da polpa em farinha concentrou significativamente os nutrientes. A farinha apresentou 28,59% de lipídios e 60,1% de carboidratos, comparados a 14,48% e 33,95% na polpa, respectivamente, enquanto a umidade de 48,9% para 5,34%. Esses valores indicam um aumento significativo no valor energético, passando de 275,68 Kcal para 517,51 Kcal. A acidez foi maior na farinha (2,56%) com pH de 4,75, o que contribui para a estabilidade do produto. Quanto à atividade antioxidante, a farinha declara uma resposta promissória, com valores de IC50 diminuindo progressivamente ao longo do tempo, reforçando seu potencial como ingrediente antioxidante. No entanto, não foram observados halos de inibição de crescimento bacteriano nas amostras, diminuindo ausência de atividade antimicrobiana contra as cepas testadas, o que sugere que o produto não afeta qualidades à microbiota intestinal. A farinha de uxi amarelo apresenta um perfil nutricional concentrado e potencial antioxidante, sendo uma alternativa viável para o desenvolvimento de produtos sem glúten e alimentos funcionais. A ausência de atividade antimicrobiana contribui para sua segurança alimentar e aplicabilidade em dietas saudáveis.
NGHIÊN CỨU CHẾ TẠO VẬT LIỆU TỔ HỢP PANi/BÃ MÍA ĐỊNH HƯỚNG HẤP PHỤ AMONI TRONG NƯỚC
Authors: Anh Nguyễn Thị Phương , Huy Phạm Quang , Ánh Nguyễn Thị Ngọc , Linh Đinh Thùy , Tiên Đỗ Thủy
Published: December 2024

Trong nghiên cứu này, vật liệu tổ hợp gốc PANi với chất mang là bã mía (PANi/bã mía) được tổng hợp bằng phương pháp hóa học và được sử dụng để hấp phụ amoni trong nước. Đặc điểm bề mặt của vật liệu PANi/bã mía được đánh giá bằng kính hiển vi điện tử quét (SEM), phổ hồng ngoại biến đổi Fourier (FTIR) và diện tích bề mặt riêng Brunauer – Emmett – Teller (BET). Khảo sát khả năng hấp phụ amoni của vật liệu thông qua nghiên cứu ảnh hưởng của pH dung dịch, thời gian hấp phụ và nồng độ amoni ban đầu. Đẳng nhiệt hấp phụ được nghiên cứu dựa trên mô hình hấp phụ đẳng nhiệt Langmuir và Freundlich. Kết quả cho thấy quá trình hấp phụ tuân theo mô hình hấp phụ đẳng nhiệt Langmuir với dung lượng hấp phụ amoni cực đại của PANi/bã mía ước tính là 87,72 mg/g ở nồng độ amoni ban đầu là 20 mg/L, pH = 6, hàm lượng vật liệu hấp phụ là 0,6 g/L và thời gian hấp phụ là 20 phút. Vật liệu tổ hợp PANi/bã mía hứa hẹn sẽ là một vật liệu có khả năng xử lý khá tốt amoni trong nước.
Digital Transformation of Local Government: Design and Development of the Pakuhaji District Community Service Information System Website
Authors: Budiarto Mukti , Asmawati Ari , Kurniawan Muhamad
Published: December 2024

In the era of digital transformation, local governments are increasingly pursuing innovation to improve the quality of public services. This research aims to carry out digital transformation in the government of Pakuhaji District, Tangerang Regency, by designing and building an efficient and responsive public service information system website. Through a systems development approach, this research identifies community needs, evaluates existing service processes, and designs information technology-based solutions. The designed information system covers various aspects of community services, such as submitting correspondence, public service information, and managing population data. The use of web technology enables better accessibility for the public, increases administrative efficiency, and speeds up the handling of service requests. The application of responsive design principles and intuitive interfaces is also a focus in website development to ensure optimal user experience. The research methodology includes a community needs survey, analysis of existing service processes, and development of a website prototype. It is hoped that the results of this research can make a positive contribution to the effectiveness and efficiency of community services in Pakuhaji District, creating a local government that is more responsive and connected to the needs of its citizens. It is hoped that this digital transformation can become the basis for further development in realizing a technology-oriented government for the welfare of society.
Harnessing AI Technologies: Innovations in Literacy Libraries for Diverse Learners
Authors: Ajwa Zalika Icasia , Patel Aroha , Moseley Anne
Published: December 2024

Technological advancements have a place in every industry, including libraries. Artificial intelligence (AI) is one technology that libraries may make use of. The authors of this study provide a detailed explanation of how libraries have evolved in the wake of disruption and note many applications of AI that could be applied in library settings. Applications of AI include helping librarians do their jobs more easily and giving users quick, effective service. But the best use of AI necessitates thoughtful thought. Literacy libraries must change to meet the requirements of various learners in this more linked and complicated society. The integration of AI technology is suggested in this article as a creative way to enhance literacy library services for students with various requirements. We investigate the potential of AI in maximizing accessibility, personalizing learning, and early detection of learning issues using conceptual analysis and observational literature. With an emphasis on equity and inclusivity, we also emphasize the opportunities and difficulties associated with implementing AI technology. A responsive, adaptable, and inclusive learning environment can be created for students of different backgrounds and skill levels by using AI into library literacy.
Evaluating How Development Methodology Software is Used
Authors: Martinez Santiago , Johannes Maxx , Tan Wei Xiang
Published: December 2024

The success of software development projects heavily relies on effective project management software and the implementation of appropriate methodologies within the System Development Life Cycle (SDLC). Selecting and implementing suitable software design and development approaches pose significant challenges due to the inherent complexity of information system implementation. Tailored methodologies that cater to the diverse needs and standards of each organization are imperative. This research aims to address the multifaceted demands of software development by evaluating the practical usage of software development methodologies in industrial settings. Through evaluative research, valuable insights into the real-world application of these methodologies, their efficacy, and the challenges faced by practitioners are uncovered. By delving into usage patterns, encountered challenges, and potential avenues for improvement, this study seeks to contribute to the refinement of software development practices within industrial contexts. Ultimately, the goal is to foster greater efficiency, effectiveness, and innovation in software development methodologies, thereby enhancing the overall success of software projects.
Network Communication Security: Challenges and Solutions in the Digital Era
Authors: Martinez Ashley , Fitzroy Arabella , Hogwart Ainsley
Published: December 2024

Network communication security is basic within the advanced age due to the developing dependence on associated gadgets and computerized innovation. This theoretical investigates the issues of the computerized time whereas analyzing issues and potential answers in this subject. It offers a rundown of security dangers and shortcomings in a few sorts of systems, counting remote, arrange cutting, and in-automobile systems. It moreover looks at machine learning and cryptography strategies for making dependable security arrangements. Furthermore, the paper offers cures for imperative security imperfections and deterrents in IoT shrewd domestic advances.The challenges in arrange communication security are various and complex. These challenges incorporate the complexity of arrange situations, advancing risk scenes, information protection and compliance, bequest frameworks integration, client mindfulness and preparing, versatility, asset imperatives, and occurrence reaction. To address these challenges, inventive arrangements are required. One approach is to embrace a all encompassing approach to arrange security, which includes considering the whole arrange foundation and actualizing security measures at each layer. This incorporates actualizing strong get to controls, such as multi-factor confirmation and role-based get to control, to guarantee that as it were authorized clients can get to arrange resources. Encryption is another pivotal component of organize security, because it secures information in travel and at rest from unauthorized get to. Data loss avoidance instruments, such as information concealing and tokenization, can moreover offer assistance anticipate delicate information from being spilled or stolen.
Artificial Intelligence in Literacy Libraries A Review of the Literature
Authors: Sithole Precious , Zirolla Eric , Lowel Simon
Published: December 2024

Technological developments bring their respective roles in all fields including libraries.One of the technologies that can be utilized in libraries is artificial intelligence. In this study, the authors explain in detail the development of libraries in the era of disruption and observe several opportunities for using artificial intelligence that can be implemented in libraries. The application of intelligence has several benefits including facilitating librarians in their work, as well as providing fast and efficient services to users. The application of artificial intelligence must be carried out optimally by considering the allocation of funds for maintenance of its infrastructure, increasing the knowledge and literacy of librarians and users about artificial intelligence technology, and adjusting the needs of users to use artificial intelligence features.
Synthetic Tannery Effluent Mixture Degradability Assessment
Authors: Minozzo O. Manuelle , Pistorello Eduarda C.S. , Queiroz Vânia , Duarte Bruno G. , Agustini Caroline
Published: December 2024

Leather is a material with unique mechanical properties, making it widely used in the production of footwear, clothing, sports articles, and in the field of coverings, such as in the automotive, furniture, marine and aeronautical industries. Leather processing involves three major stages: beamhouse, tanning, and finishing. In each of these stages, characteristic effluents are generated, which typically reach the Wastewater Treatment Plant (WWTP) mixed, for the so called end-of-pipe treatment, consisting of primary and secondary treatment. The objective of this study is to analyze the characteristics of the effluents generated in each processing stage individually and when mixed, in order to assess how the mixture impacts degradability. For the evaluation, wastewater corresponding to the three stages was generated, using raw hides for (i) beamhouse and (ii) tanning, and wet-blue leather for (iii) wet finishing. Subsequently, chemical inputs were added to the wastewater, forming synthetic effluents. The (iv) mixture of the effluent generated in the three stages was made based on the proportion of each effluent in relation to the total generated. Analyses of Biological Oxygen Demand (BOD) and Total Organic Carbon (TOC) were performed for the four samples. The BOD obtained for the mixture was zero, while the other three effluents obtained high values for the same analysis. This result indicates that an inhibitory environment to microbial growth was formed, preventing biodegradation. The TOC results indicate that the mixture contains an organic load proportional to the effluents that compose it. It was concluded that the organic load and biodegradability of the effluent can be strongly influenced by the processing methods of each tannery, such as the amount of water and inputs used, and that the secondary treatment of mixed effluents tends to be compromised compared to segregated treatment.
Lifelines
Authors: The Editors
Published: December 2024

Lifelines 119n12