bluuebunny/crossref_metadata_2025 huggingface dataset:
Neural stem cell secretome and its role in the treatment of neurodegenerative disorders
Authors: Zhang Qian , Li Jia , An Wenqiang , Fan Yiou , Cao Qilong
Published: April 2020

Neurological diseases in the central nervous system are mostly characterized by the failure of endogenous repair to restore tissue damage and salvage lost function. Currently, studies have shown that neural stem cell transplantation provides a good therapeutic effect on neurological diseases. For this reason, neural stem cell transplantation has been explored as a cell replacement therapy. Although transplanted cells can replace cells lost during or post central nervous system injury, many studies have shown that this mechanism is insufficient as most of these newly formed cells fail to integrate and eventually die. Although it was initially thought that neural stem cell could only replace lost cells, recent experiments have shown that transplanted neural stem cell can also play bystander roles such as neuroprotection and immune regulation, promote tissue repair by preventing tissue damage, interfere with pathogenic processes, or by rescuing endogenous nerve cells. However, compelling evidence has raised concerns about this bystander effect, which can be caused by several biologically active molecules (collectively known as the secretome) produced by neural stem cells. These results also raise the possibility of the neural stem cell secretome as a potential candidate for neural stem cell transplantation therapies based on the bystander effect. A better understanding of the molecules and mechanisms of this effect is of critical importance for neural stem cell-based therapies. This review aims to discuss the function and application of neural stem cell secretome in the treatment of neurodegenerative disorders.
Microneurosurgical techniques and perioperative strategies utilized to optimize experimental supracollicular decerebration in rats
Authors: Ghali George Zaki , Ghali Michael George Zaki
Published: April 2020

Decerebration permits neurophysiological experimentation absent the confounding effects of anesthesia. Use of the unanesthetized decerebrate preparation in vivo offers several advantages compared with recordings performed in reduced slice preparations, providing the capacity to perform extracellular and intracellular neuronal recordings in the presence of an intact brainstem network. The decerebration procedure typically generates variable degrees of blood loss, which often compromises the hemodynamic stability of the preparation. We describe our microsurgical techniques and discuss microsurgical pearls utilized in order to consistently generate normotensive supracollicularly decerebrate preparations of the rat, exhibiting an augmenting pattern of phrenic nerve discharge. In brief, we perform bilateral ligation of the internal carotid arteries, biparietal craniectomies, securing of the superior sagittal sinus to the overlying strip of bone, removal of the median strip of bone overlying the superior sagittal sinus, supracollicular decerebrative encephalotomy, removal of the cerebral hemispheres, and packing of the anterior and middle cranial fossae with thrombin soaked gelfoam sponges. Hypothermia and potent inhalational anesthesia ensure neuroprotection during postdecerebrative neurogenic shock. Advantages of our approach include a bloodless and fast operation with a nil percent rate of operative mortality. We allow animal arterial pressure to recover gradually in parallel with gentle weaning of anesthesia following decerebration, performed contemporaneously with the provision of the neuromuscular antagonist vecuronium. Anesthetic weaning and institution of vecuronium should be contemporaneous, coordinate, gentle, gradual, and guided by the spontaneous recovery of the arterial blood pressure. We describe our microsurgical techniques and perioperative management strategy designed to achieve decerebration and accordingly survey the literature on techniques used across several studies in achieving these goals.
The Chinese herb Fructus Broussonetiae aids learning and memory in chronic cerebral hypoperfusion by reducing proinflammatory microglia activation in rats
Authors: Liu Ping , Wang Li-ye , Wang Yu-qing , Wang Rong-liang , Li Fang-fang , Zhang Sijia , Tao Zhen , Zhao Hai-ping , Han Zi-ping , Chen Zhi-gang , Luo Yu-min
Published: April 2020

The neuroprotective role of Fructus Broussonetiae in a model of chronic cerebral hypoperfusion with cognitive decline was focused on neural plasticity and microglia/macrophage polarization. Chronic cerebral hypoperfusion was induced by bilateral common carotid artery ligation. Fructus Broussonetiae shortened escape latency and added the number of platform crossings of rats, up-regulated the expression of synaptophysin in the gray matter and increased myelin basic protein expression in the white matter. Further mechanistic experiments were conducted to examine microglia activation and M1/M2 polarization. It was shown that Fructus Broussonetiae reduced the activation of microglia revealed by decreased expression of ionized calcium-binding adapter molecule-1, inhibited M1 polarization of microglia and improved microglial M2 polarization shown by down-regulated the expression of inducible nitric oxide synthase and Fc fragment of IgG receptor IIIa and up-regulated the expression of arginase-1. In conclusion, the Chinese herb Fructus Broussonetiae can improve cognitive function following chronic cerebral hypoperfusion by down-regulating the activation of microglia, inhibiting microglial M1 polarization, and improving neural plasticity.
Stress causes cognitive impairment by affecting cholesterol efflux and reuptake leading to abnormalities in lipid metabolism of rats
Authors: Ye Ran , Zhang Miao , Zhang Song , Bai Shasha , Jiang Zhangyu , Cai Qiang , Cao Kerun , Shen Chongkun , Shi Yafei , Zhang Rong , Yang Lei
Published: April 2020

Depression is a common mental health disorder that can impair normal functions, cause distress, and adversely affect the quality of life. Cognitive impairment is considered one of the characteristics of major depression disorders-related dysfunction, and it has received attention in the treatment of major depressive disorders. To investigated the mechanisms underlying depression-induced cognitive disorders, we selected a rodent model of chronic unpredictable mild stress and used liquid chromatography/mass spectrometry-based metabolomics of sera. Behavioral tests, including the sucrose preference test and open field test, revealed that model rats developed depression-like symptoms in the sixth week of the chronic unpredictable mild stress period. Rats of the model group exhibited significant cognitive changes in the Morris water maze test in the tenth week of the period. Tau phosphorylation and decreased levels of postsynaptic density-95 and synaptophysin were observed in the rodent brains by the tenth week. These results suggest that rodents developed cognitive impairment in the tenth week of the period, while serum metabonomic showed that glycerophospholipid metabolism is the most relevant pathway to reveal the mechanism of depression-induced cognitive impairment. The disorders of lipid metabolism caused by the increased cholesterol efflux and reduced reuptake could be one of the mechanisms of depression-induced cognitive disorders. However, the relationship between cholesterol efflux in the brain and elevated serum cholesterol needs further research.
The dynamic relationship between serum chloride and cardiorenal syndrome
Authors: Kazory Amir , Rosa Costanzo Maria
Published: April 2020

Low serum sodium concentration has long been recognized as an established marker of short- and long-term morbidity and mortality in patients with heart failure (HF), and is commonly included in various risk prediction models. Mechanisms leading to hyponatremia (e.g. maladaptive neurohormonal activation) could also lead to concurrent decline in serum chloride levels. Besides, chloride has distinct biological roles (e.g. modulation of renal tubular sodium transporters) that are relevant to the pathophysiology and therapy of HF, making it a potent cardiorenal connector. Several clinical studies have recently reported on a potentially overlooked link between low serum chloride levels and adverse outcomes in patients with a wide variety of HF syndromes, which could indeed be stronger than that of sodium. While evidence on predictive value of chloride is accumulating in various patient populations and settings, the limited available interventional studies have so far yielded conflicting results. It remains to be elucidated whether hypochloremia represents a marker of disease severity and prognosis, or it is an actual pathogenetic mechanism, hence being a potential novel target of therapy. Current ongoing studies are designed to better understand the mechanistic aspects of the role of hypochloremia in HF and shed light on its clinical applicability.
Analisa tahapan metodologi audit sistem informasi
Authors: Prayoga Refki
Published: April 2020

Analisa tahapan metodologi audit sistem informasi
Identification of vaccine targets & design of vaccine against SARS-CoV-2 coronavirus using computational and deep learning-based approaches.
Authors: Abbasi Bilal Ahmed , Saraf Devansh , Sharma Trapti , Sinha Robin , Singh Shachee , Gupta Pranjay , Sood Shriya , Gupta Akshat , rawal kamal
Published: April 2020

An unusual pneumonia infection, named COVID-19, was reported on December 2019 in China. It was reported to be caused by a novel coronavirus which has infected approximately 8.7 million people worldwide with a death toll of 463000 till date. This study is focused on finding potential vaccine candidates and designing an in-silico subunit multi-epitope vaccine candidates using a unique computational pipeline, integrating reverse vaccinology and molecular docking methods. A protein named SARS-CoV-spike [S] protein of SARS-CoV-2 having GenBank ID- QHD43416.1 was shortlisted, as a potential vaccine candidate and was examined for the presence of B-cell and T-cell epitopes. We also investigated antigenicity and interaction with distinct polymorphic alleles of the epitopes. High ranking epitopes/peptides such as DLCFTNVY (B cell class), KIADYNKL (MHC Class-I) and VKNKCVNFN (MHC class-II) were shortlisted for subsequent analysis. Digestion analysis verified the safety and stability of the shortlisted peptides. Docking study reported a strong binding of proposed peptides with HLA-A*02 and HLA-B7 alleles. We used standard methods to construct vaccine model and this construct was evaluated further for its antigenicity, physicochemical properties, 2D and 3D structure prediction and validation. Finally, the vaccine construct was reverse transcribed and adapted for E. coli strain K 12 prior to the insertion within the pET-28-a (+) vector for determining translational and microbial expression. Also, six multi-epitope subunit vaccines were constructed using different strategies containing immunogenic epitopes, appropriate adjuvants and linker sequences. We propose that our vaccine constructs can be used for downstream investigations using in-vitro and in-vivo studies to design effective and safe vaccine against COVID19.
Sekapur Sirih Tentang Statistik
Authors: Jusmiana Andi
Published: April 2020

Statistik sebagai suatu ilmu yang mempelajari tentang seluk beluk data yaitu tentang tatacara pengumpulan data, pengolahan data, penganalisaan, penafsiran dan penarikan kesimpulan dari suatu data dalam bentuk angka-angka. Statistik dapat dibagi menjadi beberapa jenis berdasarkan kriteria tertentu., yaitu: 1) Berdasarkan Orientasi Pembahasan, statistik dibagi menjadi statistik matematika dan statistik terapan; 2) berdasarkan fase dan tujuan analisis, dibagi menjadi Statistik deskriptif dan Statistik inferensial; 3) berdasarkan asumsi distribusi populasi data, dibagi menjadi Statistik parametrik dan Statistik non-parametrik; dan 4) berdasarkan jumlah variabel terikat, yaitu Statistik univariat dan Statistik multivariat.
Current understanding on the Effectiveness of Face Masks and Respirators to Prevent the Spread of Respiratory Viruses
Authors: Neupane Bhanu , Giri Basant
Published: April 2020

Personal protective equipment (PPE) such as safety foot wares, gloves, face masks and respirators, face shields, and gowns are used both in health care and community settings to contain the spread of infectious diseases during microbial outbreaks. Filtering device including face masks and respirators are important components of PPE to prevent the bio-aerosol and droplet mediated transmission of a disease. In case of respiratory pathogens, droplets originate from an infected person sneezing and coughing and aerosols are formed by exhalation and desiccation of larger droplets. The filtering efficiency of a filtering device depends on nature of the filter, size and nature of particles, user preference, and environmental conditions. The breathability, facial fitness, and contamination from used mask and respirator are important factors to be considered in designing a filtering device. This review discusses on current development in materials used for filtering device, effectiveness of face mask and respirator, emerging technologies for better filtering device, and finally provide a general guideline for proper use and future prospective of face mask and respirator.
Priapismo en anestesia para cirugía urológica: alternativas terapéuticas intraquirúrgicas
Authors: Martínez Pérez Alejandro , Andrade Navas Gabriela
Published: April 2020

Introducción: El priapismo puede definirse como la erección persistente a lo largo del tiempo y en ausencia de estimulo sexual, constituye una emergencia médica, dentro de su etiología clínica pueden considerarse de dos tipos: venoso isquémico y arterial no isquémico, siendo el primero mucho más frecuente.

La ocurrencia de priapismo dentro del período intraquirúrgico es poco frecuente y puede presentarse tanto bajo anestesia general como neuroaxial, no existe literatura florida sobre este tema, por lo que se realiza una presentación de caso clínico con actualización de alternativas terapéuticas farmacológicas y anestésicas.

Objetivo: Describir un caso clínico de priapismo en anestesia para cirugía urológica.

Material y métodos: Estudio descriptivo retrospectivo, presentación de caso clínico.

Resultados: Se describe un caso clínico de paciente masculino de 33 años de edad con diagnóstico de litiasis ureteral izquierda programado para colocación de catéter doble J, litotripsia intracorpórea y cistoureteroscopia, quien presenta erección peneana permanente que no cede a profundidad anestésica y relajación muscular que imposibilitan el procedimiento quirúrgico por dificultad en la manipulación, responde adecuadamente a la administración de epinefrina intracavernosa, sin evidenciarse crisis adrenérgica ni compromiso vascular distal. 

Conclusiones: El priapismo intraquirúrgico, no es común, puede presentarse por diversas etiologías (estímulo táctil, anestesia neuroaxial y general) puede ser ocasionante de suspensiones quirúrgicas de no ser tratado pronta, adecuada y oportunamente. En la realidad de nuestro medio la técnica de inyección inracavernosa de 10 – 20 mcg de epinefrina es un método sencillo, fácil y con resultados inmediatos que permitirán la manipulación del pene para procedimientos urológicos.
La mejor evidencia científica, ante la pendemia de SARS-Cov-2
Authors: Leiva Suero Lizette Elena , Villacís Valencia Sandra Elizabeth , Quishpe Jara Graciela De las Mercedes , Chicaiza Quishpe Andrea Alejandra
Published: April 2020

Introducción: La nueva epidemia de coronavirus (SARS-CoV-2), que se informó por primera vez en diciembre de 2019 en Wuhan, China, y que ha sido declarada una emergencia de salud pública de importancia internacional por la Organización Mundial de la Salud, muestra una sustancial morbilidad y mortalidad, por tal motivo es imprescindible profundizar en los aspectos epidemiológicos, clínicos, del diagnóstico y el tratamiento para enfrentar y vencer este flagelo.

Objetivos: Revisar la mejor evidencia médica publicada y analizar el comportamiento de la pandemia por SARS-Cov-2, su epidemiología, aislamiento, manifestaciones clínicas, complicaciones, los elementos más significativos para su diagnóstico y las nuevas opciones terapéuticas disponibles, para así aprender y aplicar estas experiencias en nuevas epidemias.

Material y Métodos: Se realizó una búsqueda sistemática en las bases de datos PubMed, ProQuest, Embase, Redalyc, Ovid, Medline, DynaMed y ClinicalKey, EMBASE, LILACS durante el periodo 2019-2020 en el contexto internacional, regional y local. 

Resultados: La revisión sistemática de artículos aportó un total de 100 registros, de los cuales 62 eran elegibles; de estos, 12 no eran relevantes al objeto de esta revisión, por lo que quedaron incluidos 50.

Conclusiones: La enfermedad causada por el SARS-Cov-2, a pesar de su alta mortalidad, puede ser prevenida con aislamiento, diagnosticada oportunamente y tratada con efectividad, lo cual permitirá disminuir su impacto epidemiológico a nivel mundial. Existe un potencial arsenal terapéutico en fase de experimentación con resultados prometedores.
Atención integral a la salud de trabajadores de la terminal terrestre de Ambato, y áreas de transferencia las Américas y Cashapamba.
Authors: Hernandez Navarro Elena Vicenta , Proaño Alulema Ricardo Xavier , Caiza Vega Mónica Del Rocío , Fernández Nieto Miriam Ivonne , Chasillacta Amores Fabiola Beatriz
Published: April 2020

Introducción: Los principales aspectos del primer punto de la Declaración de Alma-Ata fueron la definición de salud y considerar la salud como un Derecho Humano Fundamental. La Atención Primaria va un paso más allá y es capaz de dispensar una atención integral y continuada, centrándose en la prevención, la promoción de la salud y en las necesidades de las personas, las familias y las comunidades a lo largo de toda su vida.

Objetivo: Detectar los problemas de salud más frecuentes en el ámbito clínico, y social en las personas de servicio el terminal terrestre y en las diferentes áreas de transferencia.

Material y métodos: Estudio explicativo observacional, de cohorte prospectivo, la población estuvo conformada por el universo de conductores terrestres durante el período septiembre 2019 – enero 2020, la muestra representada por 51 trabajadores que aceptaron ser incluidos en la investigación.

Resultados: Se demostró que existe un elevado índice de trabajadores con predisposición a diferentes enfermedades crónicas, y con estados nutricionales inadecuados los cuales pueden constituir factores de riesgo para su calidad de vida.

Conclusiones: Predominaron las enfermedades de Diabetes, hipertensión arterial, hipercolesterolemia, como predisponentes a alteraciones del equilibrio salud enfermedad, además el índice de factores nutricionales inadecuados se evidenció en el estudio.
Mathematical Learning Development using Discovery Learning Model to Improve Mathematical Understanding Skills of Students
Authors: Kartika Yuni , Murani Hutapea Nahor , Kartini Kartini
Published: April 2020

This study aims to produce a mathematics learning tool with a discovery learning model on rectangular and triangular material, with valid, practical and effective criteria to improve the mathematical understanding ability of grade VII students in junior high school. The type of research was development research with the design development using Borg and Gall. This study produced learning tools consisting of syllabus, lesson plans and student worksheets (LKPD). The results of the study showed that the learning tools met valid, practical and effective criteria. The validity of the product development was determined by expert validation with an average value of 4.46 with a very valid category. The practicality of the product development is determined by the teacher with an average of 99%, students 90.57% and observers 4.16 which is categorized as very practical while the effectiveness of the development product in terms of the achievement of learning objectives using KKM scores of 75 is obtained from the test results of mathematical understanding ability with the results there is an increase in learning outcomes using developed learning tools.
A Review of Pre-Clinical Studies for the Treatment of Neonatal Brain Injury
Authors: Kolb Bryan , Kolb Bryan , Williams Preston
Published: April 2020

The developing brain is especially sensitive to perturbations such as hypoxia-ischemia (HI) or surgical
ablation in the perinatal period. We first review and contrast the effects perinatal HI and surgical
perturbation in laboratory rats. The developing brain is also very responsive to a wide range of other
experiences that can induce remarkable neural plasticity in both the normal and perinatally injured brain.
We next review the factors that influence this plasticity in both the normal and perinatal injured. We consider
treatments that stimulate cerebral and behavioural plasticity, especially in the motor systems. The goal is to
draw attention to possible treatments that could be translated from perinatal surgical ablation to the HI model
and eventually to the clinic.
Two new species of free-living nematodes (Nematoda) from Vietnam
Authors: Tsalolikhin S.Ya.
Published: April 2020

Two new species of nematodes from the families Monhysteridae and Tobrilidae are described. Nematodes were collected from small forest ponds in North and Central Vietnam. Monhystera vietnamica sp. nov. differs from morphologically close M. uncigubernaculum Zedan, Jacobset et Geraert, 1989 mainly in longer vagina and rectum, from M. rolandi Khan et Tahseen, 2006 in longer cephalic setae and presence of ocellus. Brevitobrilus larae sp. nov. differs from morphologically close B. orientalis Tsalolikhin, 2013 mainly in longer body and longer and thinner, not hornlike cephalic setae. The genus Brevitobrilus was previously represented in Vietnam only by the species B. stefanskii (Micoletzky, 1925).
Model Auditory Intellectually Repetition (AIR) Berbantuan Video Pembelajaran untuk Meningkatkan Pemahaman Siswa
Authors: Purwanti Yuniar , Putri Munira Habibah , Rahadan Dian
Published: April 2020

Abstrak - Kemampuan siswa untuk memahami dalam mata pelajaran sejarah sangat diperlukan karena siswa perlu membangun pengetahuan baru dari pengalaman dan pengetahuan sebelumnya. Model Auditory Intellectually Repetition (AIR) berbantuan video pembelajaran dianggap sesuai untuk meningkatkan pemahaman siswa dalam Sejarah. Tujuan penelitian adalah 1) untuk mengetahui apakah ada peningkatan pemahaman siswa tentang mata pelajaran Sejarah setelah menerapkan model AIR dibantu dengan pembelajaran video dan 2) untuk mengetahui apakah peningkatan pemahaman siswa dalam mata pelajaran Sejarah menerapkan UDARA. video pembelajaran model video pembelajaran berbantuan lebih baik dibandingkan dengan yang menerapkan video pembelajaran. Metode penelitian yang digunakan dalam penelitian ini adalah metode Quasi Experimental Design yang melibatkan dua kelas Ilmu Sosial di SMAN 6 Garut sebagai kelas kontrol dan kelas eksperimen. Penelitian ini menunjukkan peningkatan pemahaman siswa tentang mata pelajaran sejarah baik di kelas kontrol dengan 25,86 dan di kelas eksperimen dengan 38,47 yang secara statistik berbeda nyata. Pemahaman siswa tentang mata pelajaran Sejarah berdasarkan Uji t menunjukkan bahwa kelas eksperimen meningkat lebih dari kelas kontrol. Pemahaman siswa tentang mata pelajaran sejarah menunjukkan peningkatan dalam menggunakan metode AIR dibantu oleh video pembelajaran dan video pembelajaran. Pemahaman siswa yang meningkat lebih baik pada model AIR yang dibantu dengan video pembelajaran.Kata kunci: Model Auditory Intellectually Repetition (AIR), video pembelajaran, pemahaman siswa
Perencanaan Sistem Informasi Pada Perusahaan PT. XYZ
Authors: Sidiq Purnomo , Nugraha Yopy , Denny Irdham , Bhakti Demmy Dharma
Published: April 2020

Abstrac - PT. XYZ is a company engaged in the manufacture of sweet soy sauce, with a segment of middle class consumers, focusing on the market share of the housewives, restaurants and traders of the wheel circumference. SI/TI in the PT .XYZ at this time not integrated in the utilization of information technology by better, of course, the very necessary development of information systems with the approach of the Architecture of the Enterprise (EA) with enterprise system manufacturing for business architecture, information architecture, application architecture and technology architecture, with method Architecture Enterprise Planning (EAP) approach framework Zachman.With planning Architecture Enterprise Planning (EAP) described in the modeling business according to the organization identified 25 business function 7 business processes, schemes of information technology are connected, the architecture of the data on the candidate data entities 41 entities, the data base tersentralisasikan accessed by all organizational units in PT. XYZ, the architecture of the application identification on candidate 41 applications, technology architecture 30 network infrastructure technology supporting business, with the aim that the process of business connected overall so that stacholder easy to plan the development of a system. Keywords - Information Systems Architecture, EAP, Information Systems, Manufacturing  Abstrak - PT. XYZ merupakan perusahaan yang bergerak dalam pembuatan kecap manis, dengan segmen konsumen menengah kebawah, berfokus pada pangsa pasar para ibu rumah tangga, rumah makan dan pedagang roda keliling. SI/TI di PT .XYZ pada saat ini belum terintergrasi pada pemanfaatan teknologi informasi dengan baik, tentunya sangat diperlukan pengembangan sistem informasi dengan pendekatan Architecture Enterprise (EA) dengan sistem enterprise manufaktur secara arsitektur bisnis, arsitektur informasi, arsitektur aplikasi dan arsitektur teknologi, dengan metode Architecture Enterprise Planning (EAP) pada pendekatan framework Zachman.Dengan perencanaan Architecture Enterprise Planning (EAP) dijabarkan dalam suatu pemodelan bisnis yang sesuai organisasi mengidentifikasi 25 fungsi bisnis dan 7 proses bisnis, skema teknologi informasi yang terkoneksi, arsitektur data pada kandidat entitas data 41 entitas, basis data yang tersentralisasikan diakses oleh semua unit organisasi di PT. XYZ, arsitektur aplikasi melakukan identifikasi pada kandidat 41 aplikasi, arsitektur teknologi 30 infrastruktur jaringan teknologi pendukung bisnis, dengan tujuan agar proses binis terkoneksi secara keseluruhan sehingga stacholder mudah merencanakan pengembangan sebuah sistem.   Kata Kunci – Sistem Informasi Arsitektur, EAP, Sistem Informasi Manufaktur
Avaliando programas de microcrédito e economia solidária do Banco do Nordeste
Authors: Gussi Alcides Fernando , Thé Raul Da Fonseca Silva
Published: April 2020

Duas experiências distintas no campo das microfinanças promovidas pelo Banco do Nordeste do Brasil são aqui avaliadas: (1) Programa Crediamigo, de microcrédito urbano produtivo orientado; e (2) Programa de Apoio a Projetos Produtivos Solidários (PAPPS), nos pressupostos da economia solidária. Para tanto, o enfoque etnográfico é apresentado como importante metodologia no desenvolvimento de processos avaliativos. Aponta-se para o alcance de sujeitos, relativamente, no mesmo grupo social, porém que se apresentam como públicos diferentes e recebem atenções, impactos e investimentos dispares sobre suas vidas e trajetórias, de acordo com os programas em que se inserem. Os resultados mapeiam como essas duas políticas, dialogam ao mesmo tempo em que diferem e se distanciam em foco e peso dados às dimensões econômicas, sociais e políticas no Nordeste brasileiro. À guisa de conclusão, evidencia-se a lógica seguida pelos programas; os impactos proporcionados na vida dos alcançados; e que qualidades, limites e possibilidades desses programas.
The Impact of an Assessment Certificate on Faculty Perceptions and Knowledge
Authors: Restrepo Jennifer L. , Perez Katherine , Sanabria Eilyn , Lebin Suzanne
Published: April 2020

Administrators are struggling to understand how to best promote and implement a culture of evidence-based decision making to stakeholders. The research study presented explored best practices on creating meaningful professional development experiences using both direct and indirect evidence of learning -- this article will describe the effectiveness of a certificate program designed to educate faculty about assessment and its impact on faculty learning gains, perceptions, and self-efficacy. The study used a pre-/post-test design to measure participant knowledge using quizzes for each of the four modules of the certificate and participant perceptions using a survey. The modules covered writing student learning and program outcomes, curriculum mapping, developing assessment methods, creating assessment instruments, collecting data, analyzing and reporting results, and using results for improvement. Certificate completers demonstrated increased knowledge of assessment terminology, procedures, and best practices, as well as improved assessment-related self-efficacy. However, their perception regarding assessment did not change. Data gathered through this study can help inform decisions on needed assessment-related faculty professional development activities.
园林绿化植物的养护管理工作研究
Authors: 周 昆
Published: April 2020

养护与管理是一项经常性的工作,必须根据园林植物的生物学特性,了解其生长发育规律,结合当地生态条件,制定一套符合实情的、科学的养护措施进行养护管理工作。本文针对当前园林绿化养护管理措施罗列,对绿化养护技术的管理进行探讨。
如何健全忠县农业气象服务和农村气象灾害防御体系
Authors: 李 佳雯 , 陈 桂琴 , 陈 伟
Published: April 2020

本文对健全忠县农业气象服务和农村气象灾害防御体系的意义进行阐述,从明确工作内容、设定建设目标、完善具体措施三个方面,对忠县农业气象服务和农村气象灾害防御体系建设要求进行解析,并以此为依据,提出健全忠县农业气象服务和农村气象灾害防御体系的相关建议。
论新形势下烧结烟气净化技术的发展
Authors: 张 锐
Published: April 2020

在群众环保意识全面提升背景下,国内制定了一系列环保政策和标准,本文通过主要是对当前国内环保政策的解决,并且对活性焦烟气净化技术的应用进行了详细研究,希望通过对相关问题解决方案的提出,能为环境建设和发展提供更有效的帮助作用。
Gerencia social como fundamento del desarrollo sustentable en el sector carbonífero venezolano.
Authors: López Juvinao Danny Daniel , Sierra Daza Leandro Amiro , Nava Chirinos Angel Alberto
Published: April 2020

Esta investigación tiene como propósito analizar la gerencia social como fundamento del desarrollo sustentable en el sector carbonífero venezolano. Se enmarca como descriptivo, no experimental, transeccional y de campo. La población estuvo conformada por 20 gerentes que laboran en las empresas carboníferas venezolanas. Se concluyó que las empresas carboníferas no identifican un patrón de cultura y valores sociales, lo que hace que estas no asuman su responsabilidad social como un elemento preponderante que estime la inserción de la empresa al contexto social, y que les permita sistematizar con su entorno, empoderarse de la necesidad social e interactuar con lo colectivo, generando así posiciones encontradas donde los sujetos del contexto social, no asumen la empresa como parte de ella, sino como generadora de situaciones divergentes con afectación social.
DIMENSI KEMISKINAN DI WILAYAH PESISIR PADA KABUPATEN INDRAGIRI HULU PROVINSI RIAU
Authors: Rahayu Heffi Christya , Sarungu J J , Hakim Lukman , Soesilo A M
Published: April 2020

This purpose of this study  to analyze the poverty of the region in Indargiri Hilir regency. This study uses panel data. The data used in this study results of Podes survey in 2003, 2006, 2008, 2011 and 2014. The sample used amounted to 465 villages. The results of variables of electric users, TVRI users, hospital distance to the village and access to hospitals have negative and significant value, indicating more and more people use electricity, TVRI and access to hospitals will reduce poverty. While the river variables for crossing between villages and rivers for transportation have positive and insignificant values, indicating that the more rivers for transportation the more poverty will increase.

Tujuan menganalisa kemiskinan  di daerah di Kabupaten Indragiri Hilir. Penelitian ini menggunakan data panel. Data yang digunakan dalam penelitian ini hasil survei Podes tahun 2003, 2006, 2008, 2011 dan 2014. Sampel yang digunakan berjumlah 465 desa. Hasil penelitian Variabel pengguna listrik, pengguna TVRI, Jarak rumah sakit  ke desa dan akses rumah  sakit mempunyai nilai negatif dan signifikan, yang menandakan semakin banyak masyarakat menggunakan listrik, TVRI dan akses rumah  sakit maka akan mengurangi kemiskinan. Sedangkan variabel sungai untuk melintas antar desa dan sungai untuk transportasi mempunyai nilai positif dan tidak signifikan, yang menandakan bahwa semakin banyak sungai untuk transportasi maka kemiskinan akan semakin meningkat.
Determinant of Islamic Banking Profitability In Indonesia
Authors: Kuswara Dimas Puja , Puji Lestari Etty , Retnaningsih Tri Kurniawati
Published: April 2020

Finding a determinant of profitability has become one of the most popular topics in banking research. Previous research has identified many factors that significantly influence bank profitability. There are also many studies that measure the effectiveness of sharia banking globally, but few analyze the profitability issues of sharia banks. This study aims to analyze the impact of factors affecting profitability in Islamic Banks listed on the Indonesia Stock Exchange. The method used is multiple linear regression analysis. The variables are return on assets as dependent variable and murabahah, musyarakah, mudharabah, branch office, cash office, and Automatic Teller Machine as independent variable. This study found that funding factors such as murabaha, musharaka and conventional and electronic networking factors such as Branch Office, Cash Office, and ATM had positive and significant impact on profitablity of Sharia Bank, while mudharabah had a negative and significant influence on profitablitas Sharia Bank. Sub-Branch Offices also had a negative but insignificant effect on the profitability of Sharia Banks. This result indicated that income on management became the most dominant income in generating profit of sharia banking. However, the management of funds could not work if not supported by Islamic banking channeling tools.
Islamic Commercial Banks and Sharia Business Units; How Efficient Are They?
Authors: Indra Kusuma Septian , Dorkas Rambu Atahau Apriani
Published: April 2020

The purpose of this study is to determine the efficiency level of Islamic commercial banks and Sharia Business Units for the period of 2012-2017 and to examine the existence of size effect in bank efficiency. Using Data Envelopment Analysis (DEA) method, this research employs total assets, deposits, and operating costs as the inputs, while the output is total financing and operating income. The samples are 11 Islamic commercial Banks and 20 Sharia Business Units. Results of this study show that Islamic commercial banks are more efficient than Sharia Business Units during the period of analysis and large Islamic commercial banks are more efficient than small sharia business units which provide evidence of size effect existence in bank efficiency. Thus, the policymaker needs to consider bank size in policy formulation regarding bank efficiency.
CONCEPT OF ‘SUCCESSFUL COLLEGE STUDENT’ IN YOGYAKARTA PROTOTYPE SEMANTICS
Authors: Kurniawan Muhammad Hafiz , Ahdiani Ulaya
Published: April 2020

Manipulation and even murder case done by student to the teacher shocked Indonesians. These unexpected phenomena happened in university – the place where the students achieve their dreams and the new knowledge to nourish their brains – because of the undergraduate thesis. Therefore, this research aimed to discover the concept of “successful college student” in the respondents’ mind. The respondents were 200 students majority from one of private universities and twodifferent universities in Yogyakarta for each method. This concept portrayed the ideal college student in their mind by revealing the most ideal and successful student, so the goal of the college students can be well-described. This research used free listing with limited time, 30 seconds as the first step of collecting the data and judging the illustration as the second one. The first method was used to create the criteria that should be included in the illustrations. Those illustrations were judged by the respondents using semantic scale, 1-7 to represent from failed to successful. The result of this research showed the gradation of member in the concept of “successful college student” was different in age, semester and discipline category but they shared common prototypical concept that the successful college student should have high GPA, be smart, diligent and religious, and should graduate on time.
TRANSLATION STRATEGIES FOR CULTURAL EXPRESSIONS IN GARUDA INDONESIA’S INFLIGHT MAGAZINE "COLORS"
Authors: Salsabila Rizky , Jumanto Jumanto
Published: April 2020

The aims of this research were to find the translation strategies, translation accuracy, and translation readability of cultural expressions in tourism texts of the Garuda Indonesia Inflight Magazine Colors. The research used a descriptive – qualitative method. To achieve the aims of this study, the researcher used some techniques to analyze the data such as reading and collecting data, encoding data, underlining the cultural expressions in the tourism texts, assessing translation accuracy, assessing translation readability, categorizing types of translation strategies and drawing conclusion. Based on the data analysis from three expert judgements, it was found that 84.5% of the data were accurate because the expressions in the target language have equivalent meaning with the source language; 15.5% of the data were less accurate because the expressions had no equal meaning with the source language and the equivalence seemed less natural; and 0% of the data were inaccurate. Meanwhile, 74% of the data were readable because the translation was very easy to understand; 16.67% of the data were less readable because the translation was not very easy to understand; and 9.33% of the data were unreadable because the translation was difficult to understand. The dominant strategy was the synonymy which got the percentage of 29%, which meant that translators also used the target language words which were more or less the same as the general source language words.
Beggars as Bully Perpetrators and General Public as Victims
Authors: Rohail Atteen , Hanif Tayyaba , Rohail Iffat
Published: April 2020

This qualitative study aimed to explore peoples’ experiences of being bullied and victimized while dealing with beggars phenomenologically. 14 Adults (7 males, 7 females) were included in the study. The age of participants was 25 years and above. The main objectives of the study were to explore how beggars emotionally victimize the general public, how do people get threatened at the hands of beggars as they exploit the publics’ emotions with the help of blackmailing tactics Therefore the Research Questions in this regard were: firstly, how people are entangled in situations and feel threatened while interacting with beggars? Secondly, what tactics are used by beggars to emotionally victimize the general public? Thirdly, how public is emotionally blackmailed by the tricks and tactics used by beggars? Phenomenological research design was used which provided a rich and detailed account of public experiences. The focus was on how people actually perceived the events rather than how the phenomena existed. Open ended questions were put forth which provided the lived experiences of the participants. Responses of the participants were transcribed and themes were generated. The major themes which emerged  were named as Anger, Exploitation, Distress, Manipulation, Fraud, Fear, Assault, Fooling public, Emotionally charging, Threatening, Stealing, Target weakness, Harassed, Monitory gain by beggars. Hence the results revealed that people do felt threatened while interacting with beggars who blackmailed them with different tricks and at times also involved in stealing, intimidation unwanted touching, name calling, cursing and even snatching the money from wallets, etc The implication of this study can be at societal or governmental level where authorities and policy makers can adopt some preventive or remedial measures for beggars and their interaction with public.
Key words: Perpetrators, Bully, Victim, General Public, Beggar, Phenomenological.
Nuclear Receptors as Regulators of Pituitary Corticotroph Pro-Opiomelanocortin Transcription
Authors: Zhang Dongyun , Heaney Anthony P.
Published: April 2020

The hypothalamic–pituitary–adrenal (HPA) axis plays a critical role in adaptive stress responses and maintaining organism homeostasis. The pituitary corticotroph is the central player in the HPA axis and is regulated by a plethora of hormonal and stress related factors that synergistically interact to activate and temper pro-opiomelanocortin (POMC) transcription, to either increase or decrease adrenocorticotropic hormone (ACTH) production and secretion as needed. Nuclear receptors are a family of highly conserved transcription factors that can also be induced by various physiologic signals, and they mediate their responses via multiple targets to regulate metabolism and homeostasis. In this review, we summarize the modulatory roles of nuclear receptors on pituitary corticotroph cell POMC transcription, describe the unique and complex role these factors play in hypothalamic–pituitary–adrenal axis (HPA) regulation and discuss potential therapeutic targets in disease states.
Produção de massa seca, volume radicular e eficiência nutricional de fósforo em Brachiaria brizantha cv. Marandu e Massai (Panicum maximum x P. infestum)
Authors: Fernandes Andre Luis Sodré , Brachtvogel Elizeu Luiz , Reis Luis Lessi
Published: April 2020

Avaliação de respostas de Brachiaria brizantha cv. Marandu e Massai a diferentes doses de fósforo. O ensaio foi conduzido em casa de vegetação no IFMT – Campus Confresa, implantado em vasos plásticos de 5dm-³ com areia grossa lavada. O delineamento experimental em blocos casualizados, combinados em esquema fatorial 5x2, com quatro repetições para cada época de coleta (30 e 60 dias após emergência). Os tratamentos consistiram em aplicações de doses de fósforo (P), via solução nutritiva, correspondentes a concentração de P em solução equivale a 0,0; 36,9; 73,8; 110,8 e 147,6 mg dm-3. Para o material vegetal coletado foi obtida a massa seca em estufa de circulação de ar e posteriormente moídas separadamente (parte aérea e raiz) para a determinação da concentração de fósforo. Os dados foram submetidos à análise de variância a nível de 5% de probabilidade pelo teste F usando software Sisvar. Observando-se efeito significativo para dose, espécie e interação doses e espécie. A espécie Brachiaria revelou-se ser mais eficiente na absorção e transporte do nutriente P do que a espécie Massai, alcançando maior produção de massa seca e raiz, evidenciando ser mais responsiva a adubação fosfatada.
An offshore transgressive–regressive mudstone-dominated succession from the Sinemurian of Skåne, Sweden
Authors: Frandsen Nils , Surlyk Finn
Published: April 2020

A Sinemurian mudstone-dominated succession was exposed until recently in the Gantofta quarry in Skåne, southern Sweden. The deposits are placed in the Döshult and Pankarp Members of the Sinemurian–Aalenian Rya Formation. Similar facies of the same age are widespread in the Danish Basin where they constitute the F-Ib unit (F-I member) of the Fjerritslev Formation. The Gantofta succession thus represents the easternmost extension of the environment characteristic of the Fjerritslev Formation and is essentially the only locality where it has been possible to study the facies of this formation in outcrop. Sedimentation seems to have taken place under relatively quiet tectonic conditions except for the possible fault-control of the basin margin. The lower part of the Gantofta section is of Early and early Late Sinemurian age. It represents the upper part of the Döshult Member and consists of muddy, lower shoreface sandstones, abruptly overlain by dark, bioturbated, fossiliferous mudstones with thin storm siltstones and sandstones. They are overlain by the Upper Sinemurian Pankarp Member which comprises red-brown, restricted marine calcareous mudstones with an upwards increasing number of storm siltstones and sandstones reflecting general shallowing and shoreline progradation. The succession spans the greater part of two simple sequences with a distal sequence boundary located at the boundary between the Döshult Member and the Pankarp Member. The exposed part of the lower sequence includes a thick transgressive systems tract and a very thin highstand systems tract. The upper sequence is represented by an undifferentiated transgressive and highstand systems tract. An Early Sinemurian sea-level rise, a late Early Sinemurian highstand, an early Late Sinemurian fall and a Late Sinemurian minor rise and a major fall are recognised. Nearby boreholes show evidence for an end-Sinemurian – Early Pliensbachian major rise. This evolution corresponds well with trends recorded in the subsurface Fjerritslev Formation of the Danish Basin. Comparison with published European and British Jurassic sea-level curves show similar overall trends, but exhibit differences in the precise ages of sequence boundaries and maximum flooding surfaces. This may reflect poor biostratigraphical resolution of the Gantofta section, differences in sequence stratigraphic interpretation, real differences in the age of sequence stratigraphic key surfaces, or the basin marginal position of Gantofta in the Fennoscandian Border Zone.
Six years of petroleum geological activities in North-East Greenland (2008–2013): projects and a view of the future
Authors: Bojesen-Koefoed Jørgen A. , Alsen Peter , Christiansen Flemming G.
Published: April 2020

The deadline for applications to the first licence round for petroleum exploration offshore North-East Greenland was 15 December 2012. The round was restricted, allowing only members of the KANUMAS consortium to be operators (BP, Chevron, Exxon, JOGMEG, Shell and Statoil). Nunaoil is also part of KANUMAS, but it is a carried, non-operator partner. An ordinary licensing round followed shortly after with a deadline on 15 October 2013.
Integrating 3D photogeology with aeromagnetic data as a tool for base-metal exploration in East Greenland
Authors: Brethes Anaïs , Guarnieri Pierpaolo , Rasmussen Thorkild M.
Published: April 2020

An 800 km long basin system developed along the East Greenland margin since the Late Palaeozoic in which the Jameson Land Basin forms the southern part of the system. Along the margins of the Jameson Land Basin there are occurrences of barite, copper, lead, zinc and silver, which are particularly abundant in the northern part of the basin’s eastern margin in the Wegener Halvø area (Fig. 1). Structures and stratigraphic architecture play important roles in the mineralisation distribution, so detailed mapping is essential. We used 3D photogeology combined with geophysical data to map the different stratigraphic units, faults and dykes in three dimensions.
To what extent is Denmark vulnerable to mineral supply shortage?
Authors: Kalvig Per , Clausen Rune J. , Fold Niels , Hanghøj Karen
Published: April 2020

Mineral resources are building blocks of modern society and essential for progress and prosperity. Mankind has always depended on access to mineral raw materials, which have been a key factor for wealth, culture and development. Modern societies are characterised by a rapidly increasing demand for specialised mineral raw materials, determined by their stage of technological development, the number of consumers, and their standard of living. Generally, the availability of mineral raw materials has not, until recently, been considered an issue by the average consumer or by companies in the downstream end of the value chains, and mineral resources have not been part of the political agenda. In this context China’s control over rare-earth elements (REE) has been an eye opener to both industry and politicians worldwide, and has subsequently led to discussions about the possible exhaustion of finite resources and potential threats to the availability of raw materials caused by geopolitical tension and market restrictions.