bluuebunny/crossref_metadata_2025 huggingface dataset:
Nurses Experience of Being a Nursepreneur in Independent Nursing Practice
Authors: Sudrajat Andi , Rejeki Yunita Fitri , Herdian Fitra
Published: November 2024

Nurses have the authority to open an independent nursing practice as one of the health services Nursepreneur is a business built based on the field of nursing the high number of nurses and the lack of independent nursing practice land into a phenomenon why nurses do not build a business in the field of nursing. Descriptive qualitative research method, sampling technique used purposive sampling and snowball sampling, with the number of informants three nurses who open nursing independent practice instrument used semi-structured interviews with data validity triangulation method and data analysis obtained five main themes. The results showed that the type of nursing independent practice established was wound care practice with a group wound care practice model, the strategic stage of establishing nursing independent practice by analyzing patient characteristics and analyzing the work environment and the regional environment, the obstacles are in the licensing flow in opening a nursing independent practice land that has not been structured and takes a long time and opportunities in mendiri nursing independent practice by branding between health agencies and through social media. Suggestions in this study need to develop quality standards for services to establish independent nursing practices and increase the involvement of professional organizations in fostering nurses who want to open independent nursing practices.
Probiotic-rich fermented milk from Lactiplantibacillus plantarum IIA-1A5: Effects on pregnancy health in the animal model
Authors: Sukma Ade , Suharto El LS. , Melia Sri , Juliyarsi Indri , Vebriyanti Ely , Fitria Najmiatul , Rahmadian Yudi , Hajrawati Hajrawati , Arief Irma I.
Published: November 2024

Previous studies of Lactiplantibacillus plantarum IIA-1A5 have shown its potential as a probiotic in modulating gut microbiota and providing health benefits; however, its effects during pregnancy remain underexplored. The aim of this study was to assess the safety of fermented milk enriched with L. plantarum IIA-IA5 in pregnant mice. An experimental study was conducted at Universitas Andalas, Padang, Indonesia. Two groups of pregnant mice (Mus musculus L.) were used, each with six mice. The control group received sterilized milk (10 mL/kg body weight (BW)), while the intervention group was given fermented milk containing L. plantarum IIA-1A5 (107 colony forming unit (CFU)/mL). The evaluated outcomes included maternal weight changes, fetal counts and measurements, and assessments of fetal morphology and skeletal development. Results indicated that the morphology of fetuses showed no significant differences between the control and intervention groups; both groups demonstrated normal development with no detected resorption sites, growth retardation, or hemorrhage. For skeletal development, both groups had the same bone counts, including frontal, parietal, intraparietal, exoccipital, supraoccipital, nasal, pre-maxilla, mandibular, thoracal, lumbar, sternum, and extremities. This study highlights that L. plantarum IIA-1A5-enriched fermented milk was safe, as no significant morphological or bone developmental abnormalities were observed, indicating its potential as a dietary supplement to support pregnancy health. However, further studies involving larger sample sizes may be needed to provide a more comprehensive assessment of its outcomes and safety.
Association between tumor necrosis factor-α gene polymorphism and interleukin-6 level with mortality of neonatal sepsis
Authors: Darnifayanti Darnifayanti , Akmal Muslim , Nur Syahrun , Yusuf Sulaiman
Published: November 2024

Sepsis is a systemic infection that significantly causes morbidity and mortality among neonates, which is associated with immature immune response. Variations in the tumor necrosis factor-alpha gene (TNF-α) -308G/A may be linked to neonatal sepsis mortality by modulating interleukins (ILs) involved in the immune response cascade, such as IL-6. The aim of this study was to investigate the association between TNF-α -308G/A gene variation and IL-6 level with mortality of neonatal sepsis. A cohort of 30 neonates diagnosed with clinical sepsis was recruited. Blood culture was performed for all patients and serum IL-6 levels were examined 24 hours after suspected sepsis. Genetic analysis of TNF-α single nucleotide polymorphisms (SNP) -308G/A was conducted using polymerase chain reaction and DNA sequencing. The association was assessed based on bivariate logistic regression. We found that 12 (40%) of 30 patients had blood culture-proven sepsis. Genotype of TNF-α -308G/A stratified of the patients was 56.7% for GA and 43.3% for GG. There were no AA variations found in this study. There was no significant association between the TNF-α -308 G/A genotype and mortality in neonatal sepsis (p=0.211). Similarly, the allelic model of TNF-α -308 gene had no association with mortality (p=0.325). Additionally, there was no association between serum IL-6 level and mortality in neonatal sepsis (p=0.253). In conclusion, SNP of TNF-α -308 gene and IL-6 level are not associated with mortality in neonatal sepsis.
Effect of walking and bone joint exercise on enhancing bone remodeling in menopausal women: A randomized controlled trial
Authors: Pasa Chusairil , Pamungkasari Eti P. , Doewes Muchsin , Purwanto Bambang , Hartono Hartono , Cilmiaty Risya , Dirgahayu Paramasari
Published: November 2024

Osteoporosis increases fracture risk and reduces quality of life in menopausal women. Although physical activity, such as walking and bone joint exercise, is known to help maintain bone health, its effectiveness needs further examination. The aim of this study was to analyze the effects of physical activity, in particular walking and bone joint exercise, on enhancing bone remodeling in menopausal women. A randomized controlled trial was conducted among menopausal women and allocated into three groups: walking, bone joint exercise, and control groups. The intervention was provided for eight weeks, with the outcomes measured before and after the intervention. The study assessed five bone remodeling biomarkers: estrogen, parathyroid hormone (PTH), receptor activator of nuclear factor kappa-β ligand (RANKL), tumor necrosis factor-alpha (TNF-α), and bone mineral density (BMD). The paired sample student t-test and ANOVA were used to assess the effects of the interventions. The results indicated that, compared to pre-intervention, both walking and bone joint exercise significantly increased the estrogen (p=0.026 and p=0.023, respectively), decreased RANKL (p=0.019 and p=0.002, respectively), decreased PTH levels (p=0.022 and p=0.048, respectively) and increased the BMD scores (p=0.001 and p<0.001, respectively). In the control group, none of the remodeling biomarkers significantly changed except the mean level of TNF-α, which was increased significantly (p=0.001). This study highlights that structured exercise, such as walking and bone joint exercise, can significantly enhance bone remodeling markers in menopausal women. Therefore, implementing such physical activities into management may provide benefits to menopausal women.
Professional Development of Teachers in the Context of STEM Education as a Relevant Psychological and Pedagogical Issue
Authors: Zavalevskyi Yurii , Lozova Oksana , Vasylashko Iryna , Chernomorets Valentyna
Published: November 2024

The article analyzes scientific research related to the issues of professional development of teachers in the context of STEM education, which is determined as a prerequisite for improving the quality of education.
It is determined that the professional development of teachers in the context of STEM education involves mastering the knowledge and skills necessary for the implementation of STEM programs and methods, adaptability and cognitive flexibility, professional self-improvement, etc. This process should be systematic and continuous and requires training and professional development during courses, scientific and practical seminars, conferences, workshops, summer schools, and other educational events.
The article presents the results of a study that highlights the psychological and pedagogical aspects of teachers' professional development in the context of STEM education, and identifies a number of problems with professional support for educators. The authors of the publication substantiate the relevance of teacher training to ensure the competitiveness and high quality of the educational process. The steps for effective professional pedagogical development in modern conditions are highlighted and a list of resources for the professional development of the teaching community in the context of STEM education is proposed.
Global Experience in Using Immersive Technologies in Geography Lessons
Authors: Nezhyvyi Oleh
Published: November 2024

The article explores the global experience of implementing immersive technologies, such as virtual (VR), augmented (AR), and mixed reality (MR), to enhance interactive learning and boost student motivation in studying geography. It provides an overview of various types of immersive technologies and their application in the educational process of institutions in Australia, Asia, North America, and Europe.
It is determined that immersive technologies involve the integration of virtual content with the physical environment, allowing users to interact with mixed reality. In the course of such interaction, virtual elements are perceived as an integral part of the surrounding environment, gradually blurring the boundaries between physical and virtual reality.
The advantages and challenges of using immersive technologies are outlined, particularly issues related to students' comprehension of educational material, the cost of equipment, and the preparation of teachers to work with these technologies. The article also analyzes the prospects for the development of immersive technologies in the education sector, specifically the potential for integrating these tools from various fields into education.
Informational and Methodical Support of Out-Of-School Education Institutions: Basic Principles and Current State
Authors: Lyaschenko Tetyana
Published: November 2024

The article reveals the essence of informational and methodical support of out-of-school education institutions. It was found that informational and methodological support is a system of necessary and sufficient conditions for the organization of the educational process, which includes a set of informational, educational, methodological and scientific materials to ensure the need for information sources.
It was determined that when developing educational and methodological materials, certain principles should be followed: scientificity, availability and reliability of information, systematicity, relevance, adaptability and innovativeness of educational materials.
The main principles of informational and methodical provision of out-of-school education institutions are characterized, in particular, the principle of legality and compliance of the regulatory and legal field; the principle of unity of purpose and goals; the principle of information security; the principle of functional structuring; optimization principle; principle of availability; the principle of sufficiency of informational and methodological support.
An analysis of the current state of informational and methodological support of out-of-school education institutions in wartime conditions was carried out by interviewing leaders of clubs and other creative associations from all over Ukraine. The exception was Zaporizhzhia, Kharkiv and Kherson regions, which, due to the hostilities, could not participate.
The level of provision of out-of-school education institutions with the necessary teaching and methodical materials for conducting classes has been determined; the quality of extracurricular education programs was analyzed; forms of improvement of the professional level of leaders of circles and other creative associations during the last five years have been clarified; the level of use of innovative forms and methods of work by teachers and which innovations are mainly used by teachers of extra-curricular education institutions is established.
It has been proven that informational and methodological support plays a key role in the system of extracurricular education, contributing to the improvement of the quality of the educational process and the effectiveness of pedagogical activities.
Leadership Qualities of the Future Officers as an Innovative Way of Developing Moral Resistance
Authors: Sokolov Artem
Published: November 2024

In today's world, where the situation is constantly escalating and new geopolitical challenges are being created, some leaders-officers possess the quality of leadership and moral stability to perform various tasks and lead their units to victory.
The author analyzes the main components of leadership that contribute to the military personnel’s effective training and determines the relationship between leadership qualities and the ability of officers to withstand moral and ethical challenges. It is especially important to pay attention to innovative methods of education that contribute to increasing the personal responsibility and moral stability of future military leaders in modern conditions. It is noted that future officers’ moral stability is a key aspect of the successful performance of tasks in conditions of danger and stress, officers must not only physical training but also a strong moral spirit that allows them to defend their principles and values, independent of complex requirements. Therefore, leadership qualities are one of the key components that contribute to the formation of moral stability of future officers of the Armed Forces of Ukraine and help create a strong foundation for professional development and success in a military career. A researched type of resilience that allows officers to remain strong and determined even in the most difficult situations without compromising their principles and duties. Leadership and moral stability, which are integral aspects of successful professional training of future officers of the Armed Forces of Ukraine, are characterized.
Critical Perspectives on the Adoption of Circular Design Strategies in the Built Environment for Sustainable Development in Sub-Saharan Africa
Authors: T. A. Suleman, , I. C. Ezema, , P. A. Aderonmu,
Published: November 2024

Adopting circular design strategies (CDS) in building development presents a transformative approach toward sustainability by promoting resource efficiency and reducing environmental impacts. This paper examined the current landscape of CDS adoption, focusing on barriers, enablers, benefits, and critical success factors within the built environment (BE) in Sub-Saharan Africa. Drawing on a comprehensive review of global contexts literature, the study identifies and categorizes 185 factors, subsequently pruning them to 121 pertinent to the design stage. Barriers such as low awareness, regulatory gaps, and economic constraints are explored alongside enablers like leadership commitment, technological innovation, and supportive policies. The paper underscores the pivotal role of these factors in shaping sustainable building practices, emphasizing the need for tailored strategies to overcome local socio-cultural, economic, and technological challenges in the BE of Sub-Saharan Africa. This research contributes a nuanced understanding of how CDS can be effectively integrated into the BE, offering practical implications for policymakers, industry stakeholders, and researchers striving to embrace sustainable practices.
Does Current Account Balance Affect Economic Growth? Evidence from Sub-Saharan Africa
Authors: T. H. Olakulehin, , O. A. Olaniyi, , A. M. Adekanmbi, , M. O. Alabi, , D. A. Babalola,
Published: November 2024

This study aimed to provide an econometric analysis of the impact of current account balances on economic growth in various subregions of Africa. It utilized the cross-sectional autoregressive distributive lags (CS-ARDL) technique and analyzed data from 1994 to 2022. The result showed that inflation has had an adverse effect on the Gross Domestic Product (GDP) in three specific regions. While the short-run influence of inflation on GDP may not be statistically significant, its long-term impact is notably negative. Foreign Direct Investment (FDI) has a negative effect on GDP in the short run; however, this effect is not statistically significant across the different economies. Over time, Foreign Direct Investment (FDI) has a negligible effect on the GDP in North Africa, but it has a negative and statistically significant influence in Central Africa. These findings emphasize the different regional dynamics in Africa and illustrate the intricate interplay between current account balances and economic growth. In conclusion this study affirmed the necessity for targeted economic strategies to combat inflation and utilize FDI for long-term growth.
Study on the Related Substance of Lamivudine by A Validated HPTLC Method in Oral Dosage Forms
Authors: R K Sangeetha , S Suganya , A S Manju , S Poomalai
Published: November 2024

Lamivudine is an anti-retroviral drug available in the formulation of tablets and oral solution. The selected compound Salicylic acid is categorized as Lamivudine impurity C. An HPTLC method was developed and validated for the estimation of Lamivudine in bulk and oral dosage forms. The chromatograms were developed using a mobile phase of methanol: water: ethyl acetate in the ratio 4:2:4, v/v/v on pre-coated plate of silica gel 60 F254 and quantified by densitometric absorbance mode at 233nm. The Rf values were 0.76±0.03 and 0.65±0.02 for Lamivudine and Salicylic acid respectively. The linearity was found to be within the range of 500-3000 ng/band for Lamivudine and 50-300ng/band for Salicylic acid. The lower limits of detection and quantification were 21.24ng/band and 64.37ng/band for Lamivudine and 8.47ng/band and 25.68ng/band for Salicylic acid. The statistical evaluation by the %RSD calculation for accuracy and precision were below 2. The validated method was applied to detect and quantify Salicylic acid in the tablets of two dosage forms and the oral solution prepared as admixture. The quantified amount of the impurity C was found to be within the limits in the tablets and not detectable in the oral solution. This method can be adopted to determine Lamivudine and its impurity C in the API and different dosage forms.
Review on Thiazolo-triazole as a Promising Anticancer Agent
Authors: Kale Jyoti D. , P.B. Akolkar
Published: November 2024

Thiazolo-Triazole is a fused ring heterocyclic system consisting of three nitrogen atoms and one Sulphur atom shows wide range of biological activities. Cancer is the second leading cause of death worldwide. In past few decades, there has been a crucial necessity for the design and development of innovative anticancer drugs that can diminish the serious health problems and unwanted side effects associated with presently used anticancer drugs. Many anticancer drugs are commercially accessible, but nonexistence of selectivity, target specificity, cytotoxicity, and development of resistance lead to serious side effects. Several experiments have been going on to develop compounds with negligible or no side effects. The thiazole and triazole heterocyclic are well-recognized to possess abundant pharmacological activities, including predominantly anticancer, as revealed by various investigations on anticancer compounds and the latest research findings pointed out that to study the anticancer potential of thiazolo-triazole compounds in single scaffold.
A Panoramic Review on Microparticles
Authors: Chatterjee Arindam , Pandey Amrita , Bansal Mayank , Sain Sunil , Sharma Ashutosh
Published: November 2024

Microparticles, microspheres, and microcapsules are common multiparticulate drug delivery systems with technological and medical benefits. Microparticles are employed extensively these days. In order to improve efficacy, tolerance, and patient compliance, microparticles are used as multi-unit drug delivery systems with clearly defined physiological and pharmacokinetic benefits. The size of their particles varies from 0.1 to 1000 μm. A range of polymers have been employed in the synthesis of microparticles for drug delivery research in an effort to boost therapeutic efficacy while reducing negative effects. These days, glass, ceramic, and polymers are used to create microparticles. This method is used to deliver medications to particular regions. Microparticles are also used for regulated, prolonged, and long-term release. to treat a variety of illnesses, including inflammation, cancer, heart disease, ocular disorders, and psychotic disorders. This review covers the pros, cons, type of microparticles, preparation method, evaluation of microparticles and applications.
Conventional and Modern Techniques to Treat Cancer
Authors: Kamble Deepti Dharmendra , Maner Saddam Shamashuddin , Jadhav Pranoti Pralhad
Published: November 2024

Cancer is global health problem responsible for one in six deaths worldwide. Treating cancer has been a highly complex process. Based on common belief, herbal medicine with the least possible side effect should be the centre of attention in cancer care. Cancer remains one of the most formidable challenges in modern medicine, with diverse forms and intricate mechanisms of progression. Cancer is a complex and multifaceted group of diseases characterized by the uncontrolled growth and spread of abnormal cells. This abstract provides a broad overview of various cancer types, highlighting their prevalence, risk factors, diagnostic methods, and treatment options. The main objective of cancer treatment is – How to discover? How to detect? How to prevent? How to treat? There are various herbal drugs that are used to treat cancer. Some mentioned drugs are as follows- curcumin, astragalus, wheat grass, green tea, garlic and ashwagandha, cinnamon and zinger etc… The most widely used traditional treatment methods are surgery chemotherapy and radiotherapy while modern modalities includes hormone therapy, targeted cell therapy, steam cell therapies, immunotherapies, radiation therapies, and antioxidants drugs. As we known some modern techniques are also used in treatment in cancer such as – Nano medicine, nano therapy, liquid biopsies and gene editing.
Lantidra: Cell Therapy for Treatment of Type 1 Diabetes Mellitus
Authors: B. Bharambe Shital , Jawarkar Shailesh
Published: November 2024

The more recent cell treatment for type 1 Diabetes is called lantidra. Lantidra has recently received approval to treat type 1 Diabetes mellitus. The first allogeneic (deceased donor) pancreatic islet cell therapy, lantidra (donislecel), was approved by the FDA Centre for Biologics Evaluation and Research (CBER) on June 28, 2023. It is intended to treat adults with type 1 diabetes who, despite current management, do not achieve target glycosylated hemoglobin levels due to recurrent episodes of severe hypoglycemia. The editorial’s goal is to draw attention to the growing impact of type 1 diabetes on the world’s health, discuss earlier attempts at pancreatic transplant techniques, and announces the first regulatory approval of a revolutionary transplant strategy called allogeneic pancreatic islet beta cell infusion.
Dispersion and Stability Behaviour of Graphene and MWCNT Based Nano-Lubricant for Vapour Compression Refrigeration (VCR) System
Authors: Cut Vira
Published: November 2024

Incorporating nanoparticles into oil compressors marks a significant advancement in scientific research. It has been widely demonstrated that the inclusion of nanoparticles can markedly improve the system's efficiency by reducing energy consumption, decreasing evaporator temperatures, and increasing condenser temperatures. Nanoparticles made of carbon, including those of metal, metal oxide, and metal hybrids, are particularly valued for their superior properties and are deemed to have considerable potential for achievements. This study focuses on examining the stability of graphene and multi-walled carbon nanotubes (MWCNT) in polyolester (POE) oil as a precursor to replacing conventional lubricating oil in refrigeration systems separately. Graphene nano-lubricants were tested at concentrations ranging from 0.1 to 0.3 g/L with the selected surfactant, cetyltrimethylammonium bromide (CTAB), in a 1:1 ratio, while MWCNT nano-lubricants were tested from 0.5 to 0.7 g/L. All samples were prepared using a two-step method that involved magnetic stirring at 1250 rpm for 45 minutes, followed by ultrasonication for 30 minutes. The samples underwent evaluation through three methods of observation. Initial visual observation was conducted immediately after production, then after a 24-hour settling period, and finally, after seven days, the three most optimal samples were identified. For MWCNT, an additional stability test was necessitated due to the high concentration levels, making it challenging to determine the three most stable concentrations. The UV-VIS spectrophotometer played a crucial role in analyzing the stability of the samples, providing data that enabled more precise results. The absorption peak at a wavelength of 294 nm reached its highest absorption value of 0.892 (a.u.) at a concentration of 0.2 g/L. In the case of MWCNT, after testing all samples, concentrations of 0.5, 0.55, and 0.65 g/L were identified as the best options based on peak absorption at different wavelengths, with their peaks at 4.87, 4.045, and 4.116 (a.u.), respectively. The Zeta Potential Analyzer confirmed the stability of these concentrations, indicating a moderate stability with values around -37.4 mV. This level of stability was also observed in MWCNT samples, with the three chosen concentrations showing excellent stability at 88.4, -84.9, and -137 mV, respectively. Among all tested nano-lubricant samples, those with concentrations of 0.2 g/L and 0.65 g/L for Graphene/CTAB/POE and MWCNT/POE, respectively, demonstrated the highest stability and optimum performance. This suggests that these concentrations have the potential to serve as replacements for POE oil in refrigeration systems.
Marketing Management in Ed-tech: Innovations and Challenges in Promoting Educational Technologies
Authors: Arvindbhai Santoki Ashwinkumar
Published: November 2024

In the rapidly evolving field of educational technologies (Ed-tech), effective marketing management is crucial for promoting innovations and engaging a diverse audience. This research explores the use of AI-driven predictive analytics to optimize marketing strategies in the Ed-tech industry. By harnessing vast amounts of user data, predictive models are employed to identify emerging trends, anticipate customer needs, and personalize marketing content. This approach enhances the relevance of promotional efforts and improves conversion rates. However, the application of AI in this domain also poses challenges, such as ensuring data privacy, managing biases in predictive models, and balancing personalization with ethical marketing practices. The research provides insights into the innovations AI brings to Ed-tech marketing while addressing the challenges that need to be navigated to fully leverage its potential. This framework offers a strategic blueprint for Ed-tech companies to stay competitive in a crowded marketplace.
IMPLEMENTATION OF CUSTOMS PROTECTIONISM ON THE EXAMPLE OF MEAT INDUSTRY ENTERPRISES IN THE NORTH-WEST
Authors:   St. Petersburg State University of Aerospace Instrumentation, Bondar Elena G.
Published: November 2024

The article examines the instruments of customs protectionism (including tariff incentives, tariff quotas) used in Russia to regulate the meat and meat products market. The official statistical indicators reflecting the volume of imports and the vol- ume of domestic production of meat products are analyzed. It is determined that the necessary level of food security has been achieved in Russia in terms of the provision of meat products included in the list of socially significant products. It has been es- tablished that the North-Western region remains dependent on imported meat products, as a result, the instruments of customs protectionism are sensitive for participants in foreign economic activity.
THE ROLE OF THE NORTHWESTERN FEDERAL DISTRICT IN ENSURING SUSTAINABLE INNOVATIVE DEVELOPMENT OF THE RUSSIAN FEDERATION
Authors:   St. Petersburg State University of Aerospace Instrumentation, Kornilova Svetlana V. , Vakhromeev Boris A. ,   St. Petersburg State University of Aerospace Instrumentation
Published: November 2024

The article is devoted to the innovative development of the Russian Federation, both in general and in the regional context for the period from 2014 to 2022. The scientific research is based on statistical data for the open period. The purpose of the study is to identify the role of the Northwestern Federal District in the innovative development of the Russian Federation through indicators of financing scientific activities, costs of innovative research in the context of types of work and subjects. The results obtained confirm the potential of sustainable innovative development of the Russian Federation, the significant place in it of the North-Western Fed- eral District and can be applied for strategic planning of measures for the implementation of innovative development
D YNAMICS OF BUSINESS DEMOGRAPHICS OF ORGANIZATIONS IN THE DIGITAL ECONOMY AND ITS IMPACT ON APPROACHES TO PERFORMANCE ASSESSMENT
Authors:   Peter the Great St. Petersburg Polytechnic University, Bondarenko Sergei A. , Pupentsova Svetlana V. ,   Peter the Great St. Petersburg Polytechnic University
Published: November 2024

The relevance of the research is justified by the change in the external environment of organizations’ activities, which is manifested in the integration of ICT technologies into the sphere of organizations’ activities. The turbulence of the external environment also affects the business demography of organizations that require detailed analysis. The study presents the cur - rent structure of organizations in the cross-section of various organizational and legal forms and reveals the current share of non-financial corporations in the gross value added of Russia. Shows changes in the business demographics of domestic com- mercial organizations by form of ownership, current number, opening and closing in the 21st century. The dynamics of activity in the registration of new IT-organizations and in the use of special software by commercial organizations is reflected, and the dynamics of IT-industry development by main indicators is revealed. The growth of the share of IT-organizations in the total number of different organizations over time is revealed. The influence of the dynamics of development of business demogra- phy of commercial organizations on the established approaches to assessing the effectiveness of their activities has been es - tablished. The necessity to revise these approaches in the conditions of the digital economy has been substantiated, and the corresponding proposals have been put forward.
Breaking the Lock through Gender Responsive Workplace Practices in e-Commerce at GittiGidiyor
Authors: Uru F. Oben , Vardarlier Pelin , Mujtaba Bahaudin G. , Yozgat Ugur
Published: November 2024

Gender responsive workplace practices which promote economic development progress and lead to a more sustainable future for the work life are on the agenda globally. Notwithstanding that the importance and promotion of gender responsive workplace practices has been recognized and accelerated in recent years; these practices have not reached the desired level worldwide yet. Thus, it is important to share and increase the number of best practices that businesses should perform on gender equality. Considering the importance of this subject, in the literature, gender responsive workplace practices have not been adequately addressed, especially in developing countries. To fill this gap in the field, in this study, we aim to reveal gender responsive workplace practices by opening a new door on this issue while grounding the subject on the New Institutional Theory and Feminist Institutionalist Paradigm at the macro level, and on the Strategic Human Resources Management (SHRM) and its sub-branch Diversity and Equality Management Systems (DEMS) at the micro level. Hence, we explain this issue by analyzing it in-depth via a case study in leading gender responsive workplace practices in the context of a developing country, Turkey. The results indicate that gender responsive workplace practices are put into practice by following acquiesce strategy and with SHRM and DEMS.
Knowledge of self-care among heart failure patients at Vinmec Times City International Hospital In 2023
Authors: Tran Thi My , To Thi Huyen Sam , Nguyen Thanh Tra , Tran Thi Nhinh , Giang Tri Thanh
Published: November 2024

Background: The study aims to describe the knowledge of self-care among heart failure patients at Vinmec Times City International Hospital in 2023. Method: A cross-sectional descriptive study was conducted on 246 diagnosed heart failure patients undergoing outpatient treatment at the Cardiology Department of Vinmec Times City International General Hospital from April 2023 to October 2023, using the Atlanta Heart Failure Knowledge Test (AHFKT – V2) to assess patients' knowledge of self-care. Results: The proportion of heart failure patients with adequate self-care knowledge was very low (19.5%), with basic knowledge about heart failure reaching 27.2%, knowledge about medication and adherence to treatment reaching 6.1%, knowledge about symptom control and self-care practice reaching 5.3%, and knowledge about nutrition reaching 5.7%. Patients with an education level of secondary vocational school or higher have better self-care knowledge compared to those with a basic education level (OR = 5.3; p < 0.001). Conclusion: The proportion of heart failure patients with knowledge of self-care during outpatient treatment at Vinmec Times City International Hospital is relatively low and there is a correlation between educational level and self-care practices among heart failure patients. It is essential to implement measures to enhance self-care knowledge among outpatient heart failure patients, such as health education interventions, monitoring, and timely support to supplement knowledge. Keywords: self-care; knowledge; heart failure.
The desire to work abroad of regular bachelor of nursing students and associated factors at the University of Medicine and Pharmacy, Hue University
Authors: Nguyen Van Hiep , Nguyen Thi Khoa Nhu , Tran Van Son , Le Hoang Anh Quan , Nguyen Minh Tu , Nguyen Thanh Gia
Published: November 2024

Background: With the economy developing towards globalization, workers going abroad to work is a common phenomenon, including bachelor of nursing. Objective: To describe the desire of bachelor of nursing students at the University of Medicine and Pharmacy, Hue University, to work abroad, and to identify some associated factors. Methods: A cross-sectional study was conducted on all bachelor of nursing students from November 2023 to January 2024. Multivariable logistic regression was performed to identify associated factors. Results: Among 693 students, 52.1% wanted to work abroad. Desire to work in Germany and Japan accounted for 65.7% and 21.1%. The purpose of financial support for the family was 24.5%. Foreign language barriers were 32.3%, and professional qualifications were 20.2%. Factors associated with the desire to work abroad included first-year students (OR= 4.11; 95% CI: 1.08-15.66), third-year students (OR= 2.45; 95% CI: 1.59-3.77), and having ever heard of career guidance (OR= 1.82; 95% CI: 1.18-2.82). Conclusion: It is necessary to encourage students to learn about working abroad programs and improve their foreign language skills and professional qualifications. Keywords: Student, nursing; working abroad.
Differences between self-perceived and objectively measured body composition in HIV patients using InBody
Authors: Thanh Thai Truc , Thao Thi Ngo Vy , Thu Thi Pham , Phuong , Trong Tran  Vo Binh , Quoc Trung Huynh Hieu , Hy Thi Bui Han
Published: November 2024

Introduction: Body composition is a critical aspect of health, particularly for individuals living with HIV. This study investigates the differences between self-perceived body composition and objectively measured body composition using the InBody machine in HIV outpatients. Methods: A total of 383 HIV-infected outpatients receiving ARV treatment were invited to participate. Patients’ perceptions of their weight, muscle mass, fat mass, water, and mineral content were collected through face-to-face interviews. Subsequently, patients underwent body composition analysis using the InBody machine, and the data were classified into three groups according to each individual’s reference level. Results: Among the 383 patients, 77.5% were male, with the highest age group being 30–45 years, accounting for 56.1%. Nearly two thirds (66.3%) of the patients had been living with HIV for five years or more. The results revealed significant differences between patients’ perceptions and the objective measurements of body composition in 4 out of 5 indicators, except for fat mass. Conclusion: Self-perception of health is important as it influences decisions to seek medical services and other forms of assistance. The discrepancies between HIV patients’ perceptions of their body composition and objective measurements highlight the necessity of regular body composition assessments and improved patient education to enhance health outcomes. Keywords: Body composition, HIV, ARV, Inbody, outpatient
ON TENSORS AND THE VOLUME ELEMENT OF 푳ퟏ
Authors: Karagöz Serpil
Published: November 2024

In this work, we give the relationship between the alterne tensor 풅풆풕∈푱풏(푳ퟏ풏)which is the volume element of 푳ퟏ풏and the symmetric tensor inner product on푳ퟏ풏
Understanding tuberculosis: Examining its historical impact, modes of transmission, risk factors, and strategies for global prevention and effective treatment
Authors: Alharbi Abdulrhman Awadh , Al-Arej Ibrahim Muhammad , Alsayegh Abdullatif Suliman , Al Owias Meshal Ibrahim Zaid , Alanezi Bader Sayah
Published: November 2024

Background: Tuberculosis (TB) is a highly infectious disease with a long history of impacting global health. Despite the availability of effective treatments, TB remains a significant cause of morbidity and mortality, particularly in low- and middle-income countries and among HIV-positive individuals. TB transmission occurs primarily through inhaling aerosolized droplets from an infected person, leading to potential disease progression. Risk factors for TB include close contact with infected individuals, residency in TB-endemic regions, and immunocompromising conditions like HIV and diabetes. Aim: This article aims to provide an overview of TB’s historical impact, modes of transmission, risk factors, diagnostic methods, and global strategies for prevention and treatment. Methods: The review synthesizes data from recent studies on TB transmission, clinical symptoms, imaging techniques, and diagnostic tests, including acid-fast bacilli (AFB) smear, nucleic acid amplification tests (NAATs), and immune-based tests. Various diagnostic and treatment protocols are discussed for both drug-susceptible and drug-resistant TB strains. Results: TB diagnosis relies on a combination of imaging, microbiologic testing, and immune-based tests. While AFB smears and NAATs remain primary diagnostic methods, novel imaging techniques like CT and PET scans are expanding diagnostic accuracy.
Cushing's syndrome: An in-depth review of pathophysiology, diagnosis, and manifestations
Authors: Alfawaz Farah Saeed , Alsaadi Mona Mudlah , Alotaibi Suhoud Saud , Al Anazi Nouf Ayes , Alotaibi Areej Bader , Al-Arej Ibrahim Muhammad , Alsayegh Abdullatif Suliman , Alduaybi Mohammed Abdullah , Al Owias Meshal Ibrahim Zaid , Alnughaymishi Ahmed Abdulkarim Sulaiman , Aldawsari Hamad Fahad Hamad , Alqahtani Asma Saad , Alanezi Bader Sayah , Al-Shuwayman Abdullah Abdulrahman
Published: November 2024

Background: Cushing's syndrome results from prolonged exposure to elevated glucocorticoids, leading to significant morbidity and mortality. Despite its historical identification over a century ago, challenges remain in diagnosing and treating this condition due to its non-specific symptoms and complex underlying mechanisms. Aim: This review aims to elucidate the pathophysiology, diagnostic approaches, and treatment options for Cushing's syndrome to enhance clinician understanding and improve patient outcomes. Methods: A comprehensive literature review was conducted, synthesizing data on the etiology, classification, and epidemiology of Cushing's syndrome. The review categorized Cushing's syndrome into ACTH-dependent and ACTH-independent forms, highlighting diagnostic challenges and therapeutic strategies, including surgical, medical, and radiation options. Results: The findings reveal that Cushing's syndrome predominantly arises from either endogenous factors (e.g., pituitary adenomas, ectopic ACTH production) or exogenous glucocorticoid use. ACTH-dependent Cushing's disease accounts for the majority of cases, particularly in women aged 25-40. The review also identifies key diagnostic tools, including biochemical tests and imaging studies, and discusses the importance of recognizing both overt and subtle clinical presentations. Conclusion: Cushing's syndrome remains a complex endocrine disorder requiring a multifaceted approach for accurate diagnosis and effective management.
THE POLITICAL HEARTLAND OF CHAGATAI KHAN IN ZHETYSU
Authors: O. Oshanov
Published: November 2024

The article examines the history of Zhetysu, during the period when this historical region was part of the Chagatai’s ulus. Special attention is paid to the Kegen-Narynkol district, which was the political center of this Ulus. The historical significance of this region is insufficiently covered in historical research. Kegen-Narynkol district is considered the seasonal political center of Chagatai and his descendants, their summer pastures were located here. It also describes the artificial ponds (reservoirs) preserved to this day in the Kegen-Narynkol steppes, the construction of which is associated with the rulers of the Chagatai Ulus. At the end of the article, the political situation in Kegen-Narynkol during the existence of the Kazakh Khanate under the rule of Yesim and Zhangir, as well as the general history of the Kazakh and Kyrgyz peoples, is investigated. The article uses information from written sources, as well as historical legends, pedigrees preserved by the Kazakhs and Kyrgyz.

В статье рассматривается история Жетысу, в период, когда эта историческая область входила в состав Улуса Чагатаидов. Особое внимание уделяется Кеген-Нарынкольскому региону, который являлся политическим центром этого улуса. Историческое значение этого региона не получило должного освещения в исторических исследованиях. Кеген-Нарынкольский район рассматривается как сезонный политический центр Чагатая и его потомков, здесь находились летние пастбища Чагатаидов. Также дается описание сохранившихся до наших дней в Кеген-Нарынкольских в степях искусственных прудов (водоемов), сооружение которых связывается с правителями Чагатайского улуса. В завершении статьи исследуется политическая ситуация в Кеген-Нарынколе в период Казахского ханства в правление Есима и Жангира, а также общая история казахского и кыргызского народов. В статье использованы сведения письменных источников, а также исторические легенды, родословные, сохранившиеся у казахов и кыргызов.
ОРНАМЕНТИРОВАННЫЕ ФАЛАНГИ ЖИВОТНЫХ НА ПОСЕЛЕНИЯХ БОТАЙСКОЙ КУЛЬТУРЫ: АРХЕОЛОГИЧЕСКИЙ КОНТЕКСТ, ОСОБЕННОСТИ ДЕКОРА И ИНТЕРПРЕТАЦИЯ
Authors: Э.Р. Усманова , С.В. Захаров , И.В. Палагута , В.К. Мерц , А.А. Плешаков
Published: November 2024

Находки орнаментированных фаланг лошадей и других копытных животных — характерная особенность культур энеолита степей Евразии. Коллекция орнаментированных путовых костей преимущественно лошади (реже — кулана и сайги) из поселений ботайской культуры Ботай и Красный Яр I (Северо-Казахстанская обл., Казахстан) насчитывает 78 изделий. Это самая большая серия орнаментированных фаланг, известная по материалам евразийских древностей. Предположение о том, что они представляют своеобразную разновидность антропоморфной пластики неоднократно высказывалось ранее. Поселение Ботай является уникальным по обилию остеологического материала: 99% — принадлежало лошади. Жизнь «ботайцев» была тесно связана с популяцией лошади лесостепного Приишимья. Фаланга копытного животного, устойчивая в вертикальном положении, по форме напоминает антропоморфную фигурку. Перед нанесением орнамента фаланга обрабатывалась. Планиграфический анализ находок указывает на их повсеместное присутствие в жилом пространстве ботайского поселения. Возможно, они играли роль идолов-оберегов, охранявших жилое пространство и/или в каком-то виде изображали взаимоотношения человека и лошади.

Finds of ornamented phalanx bones of horses and other ungulates are typical for the Eneolithic cultures of Eurasian steppes. The collection of ornamented fetlock bones, mainly of horses (less commonly, of kulan and saiga) from the Botai culture settlements of Botai and Krasny Yar I (North Kazakhstan Oblast, Kazakhstan) includes 78 items. It is the largest series of ornamented phalanges known in the materials of Eurasian antiquities. The assumption that they represent a distinctive type of anthropomorphic figurines, has been repeatedly expressed earlier. The Botai settlement is unique in terms of the abundance of osteological material: 99% belonging to horses. The life of the “Botai people” was closely connected with horse population of the forest-steppe region. The phalanx bone of a hoofed animal, stable in vertical position, resembles by its shape an anthropomorphic figurine. A phalanx was processed before applying decoration. Planographic analysis of the finds indicates their ubiquitous presence in the living space of the Botai settlement. Perhaps, they played the role of idols-charms that protected the living space, and/or in some ways represented the relationship between a man and a horse.