bluuebunny/crossref_metadata_2025 huggingface dataset:
Valorization of bioactive metabolites from Trichodesmium erythraeum bloom biomass for vector borne disease control, bactericidal and anticancer therapy
Authors: Surya Parthasarathy , Seema Siddharthan , Salmen Saleh H. , Aljawdah Hossam M. , Sundaramanickam Arumugam
Published: October 2024

In the marine environment, algae are regarded as globally distributed entity. The excessive accumulation of nutrients such as nitrogen or phosphorus causes an algal bloom, which is caused by the rapid growth of microscopic algae rather than macroscopic ones. Even though it has negative effects, its significance in terms of biological usage was limited to experimental perspective. In our study, we have utilized algal waste biomass of Trichodesmium erythraeum to valorize its natural metabolites for the vector control, bacterial inhibition and anticancer study. Among the solvents, the methanolic extract produced significant mosquitocidal action against A. stephensi, A. aegypti, and C. quinquefasciatus. The methanolic extract of T. erythraeum were found to inhibit the growth of clinical pathogens including B. subtilis, P. mirabilis, S. aureus, E. coli and K. pneumoniae. Further, the methanol extract mediated anticancer effect was assessed on non-small cell lung cancer cell lines. Moreover, the extract displayed no impact on non-target organism. FT-IR results suggested the incidence of alkanes (–C ≡ C–H: C–H stretch), nitrile (C ≡ N), (primary amines (N–H bend), aliphatic amines (C–N stretch), alkenes (= C–H bend) and nitro compounds (N–O asymmetric stretch). GCMS analysis listed the series of compounds such as Hexadecanoic acid, Bicyclo [10.1.0] tridec-1-ene, Glycidol stearate, Tricyclo [20.8.0.0 (7, 16)] triacontane, 1(22), 7 (16)-diepoxy- and Piperidine played vital role in vector control and bactericidal action. This study specifies on usage of algal metabolites and the obtained results imply that it might be useful for essential medicinal applications.
The Role of Quantum Metastability and the Perspective of Quantum Glassiness in Kitaev’s Fractional Spin Dynamics: An NMR Study
Authors: Papavassiliou Georgios , Papawassiliou Wassilios , Lazaridis Nicolas , Mpanga Eunice Mumba , Koppe Jonas , Panopoulos Nikolaos , Karagianni Marina , Gkoura Lydia , Berthelot Romain , Fardis Michael , Pell Andrew
Published: October 2024

The suppression of magnetic order and the detection of a half-quantized thermal Hall effect in α-RuCl3 under an external magnetic field have sparked significant debate, whether these phenomena point to spin fractionalization, as posited by the Kitaev quantum spin liquid (QSL) model, or if they arise from a more conventional mechanism in an antiferromagnetically ordered spin state. Here, through 23Na NMR relaxation measurements on the layered cobaltate Na2Co2TeO6 at two distinct magnetic fields (4.7 and 9.4 Tesla), we provide compelling evidence supporting a variant interpretation. While upon cooling, the NMR relaxation times align with the temperature dependence predicted by Kitaev’s fractional spin excitations, below 10 K, a dynamically heterogeneous state is detected with Quantum Spin Glass (QSG) characteristics. In this state, the spin fractionalization dynamics unfold over markedly different time scales, and are characterized by quantum metastability, inducing prolonged equilibration as T→0. This observation challenges the prevailing view of a primarily homogeneous QSL state, as the ground state of tangible Kitaev systems.
miRNA-223-5p Inhibits Hypoxia-induced Apoptosis of BMSCs and Promotes Repair in Legg-Calvé-Perthes Disease rabbit model by Targeting CHAC2 and Activating the Wnt/β-catenin Signaling Pathway
Authors: Yang Jiafei , Zhang Tianjiu , Zhu Xingtao , He Zhexi , Jiang Xu , Yu Song
Published: October 2024

Legg-Calvé-Perthes disease (LCPD) involves femoral head osteonecrosis due to disrupted blood supply, leading to joint deformity and early osteoarthritis. This study examines the role of miRNA-223-5p in regulating hypoxia-induced apoptosis and promoting osteogenesis in bone marrow mesenchymal stem cells (BMSCs). Using a juvenile New Zealand white rabbit model of LCPD created through femoral neck ligation, we transfected BMSCs with miR-223-5p mimics, inhibitors, and controls, followed by hypoxic exposure. We assessed the impact of miR-223-5p on BMSC apoptosis using qPCR, Western blotting, and dual-luciferase reporter assays, focusing on the Wnt/β-catenin signaling pathway. In vivo, we evaluated the effects of transplanting miR-223-5p-overexpressing BMSCs into the LCPD model. Our findings indicate that miR-223-5p is downregulated under hypoxic conditions. Overexpression of miR-223-5p in BMSCs inhibited hypoxia-induced apoptosis and activated the Wnt/β-catenin pathway through direct targeting of CHAC2. In vivo, miR-223-5p-overexpressing BMSCs enhanced femoral head osteogenesis and reduced necrosis in the LCPD model. These results suggest that miR-223-5p inhibits hypoxia-induced apoptosis in BMSCs by targeting CHAC2 and activating the Wnt/β-catenin pathway, proposing miR-223-5p as a promising target for improving bone repair in ischemic conditions.
BSPKTM-SIFE-WST: Bispectrum based Channel Selection using Set-Based-Integer-Coded Fuzzy Granular Evolutionary Algorithm and Wavelet Scattering Transform for Motor Imagery EEG Classification
Authors: KARDAM VIKRAM SINGH , TARAN SACHIN , PANDEY ANUKUL
Published: October 2024

Background
A brain-computer interface (BCI) is a system that makes communication between the brain and an external device. The electroencephalogram (EEG) is the most favourable tool for extracting neural signals from the brain. Motor Imagery (MI) based BCI with EEG signals is an active BCI paradigm. The performance of MI-based BCI is easily affected by noise and redundant information. To decrease noisy and redundant information and increase the spatial resolution of the EEG signals, a multichannel EEG-based BCI system is used. However, high-dimensional data from multichannel BCI systems has serious impact on the classification performance. Therefore, for better classification performance of EEG-based BCI systems, channel selection methods are used. Generally, many traditional signal processing techniques such as correlation and power spectrum have been used for feature-based channel selection. However, the estimation of the power spectrum discards the phase relationship among frequency components.
Methods
To solve this problem, a bispectrum (BSPKTM) based channel selection technique is used to overcome the drawback of the power spectrum. It effectively provides the frequency domain information of MI related brain activities. Therefore, in this study, a bispectrum-based channel selection algorithm is proposed for the MI-based BCI system. The most relevant channels from bispectrum analysis are selected from bispectrum analysis using a set-based integer-coded fuzzy granular evolutionary algorithm (SIFE). The features are extracted from the selected channels using wavelet scattering transform (WST).
Results
Finally the experiments are tested on multiple classifiers and best performance is obtained using the SVM classifier. The best results are obtained as accuracy 96.78%, sensitivity 93.58%, specificity 94.64%, F1-score 0.9403, and kappa value 0.8821. The other classifiers also attained significant results using minimum number of EEG channels.
Conclusions
The proposed work explores the utility of channel reduction using BSPKTM-SIFE and WST based features extraction for the classification of left hand and right hand MI tasks EEG signals.
Do your employees really thrive or just (barely) survive? Exploring the potential benefits of having frontline home care professionals that thrive at work
Authors: Mutonyi Barbara Rebecca , Slåtten Terje
Published: October 2024

Background This study explores thriving at work (TAW) as an influential aspect of employees’ experience of their organization and work conditions. TAW concerns whether employees are energized and feel alive as members of an organization. Although TAW is essential for organizations, few studies have focused specifically on TAW within a healthcare context. In particular, research has not considered the potential benefits of frontline TAW for employees. The aim of this study is to examine a broad selection of potential benefits of TAW to individuals. Three types of benefits are explored: (1) job performance, (2) creative performance, and (3) learning. Each of these types involves two factors, representing the potential outcomes or benefits of TAW in each category. No previous research has explored the benefits of TAW as extensively as this study. Consequently, this study is unique and contributes to a relatively overlooked subfield of health services research. Methods This study utilized a crosss-sectional survey in nine home care insitutions in Norway, with a total ofN = 258 home care professionals in Estern-Norway. The study analyzed its data with the Stata 17 program, using the SEM (structural equation modeling) method to measure the direct proposed relationships. Results The results reveal that frontline home care professionals’ level of TAW is positive for each of the three categories examined. Specifically, the individual benefits of TAW in each category are as follows: first category (job performance), service quality of care (β = 0.46) and work productivity (β = 0.46); second category (creative performance): individual innovative behavior (β = 0.39) and creativity (β = 0.37); third category (learning): learning orientation (β = 0.40) and relationship learning (β = 0.49). Conclusions Frontline home care professionals’ TAW level is directly linked to many desirable individual benefits. Consequently, managers of healthcare organizations should take the TAW of their frontline employees seriously. Specifically, they should inspect and closely follow how the TAW in their organization may change over time. This requires organizations to track the TAW of their frontline employees continuously, and if it falls, managers should quickly identify the root cause and implement policies to return it to an acceptable level. Therefore, managers should focus on and continually foster the TAW of their employees. As our results demonstrate, TAW is a multipurpose tool that can successfully achieve numerous desirable and important benefits in healthcare organizations.
Reanalysis of cryo-EM data reveals ALK-cytokine assemblies with distinct stoichiometries
Authors: Savvides Savvas , Felix Jan , De Munck Steven , Bazan Fernando
Published: October 2024

Anaplastic lymphoma kinase (ALK) and leukocyte tyrosine kinase (LTK) are receptor tyrosine kinases activated by their cognate ligands ALKAL2 and ALKAL1 resulting in pleiotropic signalling outputs in development, metabolism and cancer. Structural studies by X-ray crystallography and electron cryo-microscopy (cryo-EM) recently revealed distinct assemblies corresponding to ALK-ALKAL2 and LTK-ALKAL1 assemblies with either 2:1 stoichiometry versus ALK-ALKAL2 complexes with 2:2 stoichiometry. Here, we report the reanalysis of cryo-EM data deposited by Reshetnyak et al. (EMPIAR-10930) and show that over half of the particles in the dataset correspond to ALK-ALKAL2 complexes obeying a 2:1 stoichiometry besides the originally reported structure displaying 2:2 stoichiometry. Our workflow critically relied on extensive particle orientation rebalancing in cryoSPARC followed by 3D refinement with Blush regularization in RELION leading to a 3D reconstruction of the 2:1 ALK-ALKAL2 complex to 3.2 Å resolution. This cryo-EM structure together with the reported crystal structures of ALK-ALKAL2 and LTK-ALKAL1 complexes with 2:1 stoichiometry, reconcile a common receptor dimerization mode for ALK and LTK poised for the facile juxtapositioning of their intracellular kinase domains for signalling.
Characterization of Respiratory, Skin, and Cloaca Microbiota in Mediterranean Loggerhead and Green Sea Turtle Populations
Authors:   Vanessa M. Bachmann1 M. Bachmann, Hochscheid Sandra , Affuso Andrea , Pace Antonino , Lalzar Maya , Levy Yaniv , Kan Gaston , Rybak Olga , Tchernov Dan , Morick Danny , Meron Dalit
Published: October 2024

Animals are considered biological units with their microbiota, which is composed of commensal, pathogenic, and symbiont bacteria. This microbiota is shaped by the environment and through changes in the animal life history, and it plays a key role in the physiology and fitness of its host. Sea turtles are known to be good indicators of marine ecosystem health, and it is known that their populations are declining in the Mediterranean. Herein, we characterize the upper respiratory, cloaca, and skin microbiota of loggerhead sea turtles under rehabilitation at the Israeli Sea Turtle Rescue Center located in Mikhmoret, Israel, and the Stazione Zoologica Anton Dohrn located in Napoli, Italy to compare sea turtles’ microbiota in the Eastern Mediterranean Sea (EMS) and the Western Mediterranean Sea. Furthermore, we characterize the breath, skin, and cloaca microbiota of green sea turtles kept in captivity for conservation purposes at the Israeli Sea Turtle Rescue Center. Our results showed significant composition differences between the three groups of sea turtles, their surrounding water, and between the organs assessed within and between species. Additionally, we identified core bacterial taxa for the organs sampled in each sea turtle group. The dominant bacteria in all turtle groups belonged to the Gammaproteobacteria, Bacteroidia and Alphaproteobacteriaclasses. Our study is the first one to enable the comparison of the microbial composition of two loggerhead populations in the Eastern and Western Mediterranean. The results aligned with previous findings regarding the dominant bacterial groups and constituted baseline data for the core microbial communities’ composition on wild chelonians as sentinel species in the Tyrrhenian and Levantine basins. The differences in the bacterial profile enable the identification of the turtles' species, sex, and environment. Changes in the microbiota can also indicate their health status. Additionally, the microbiome characterization of the Israeli green sea turtle population allows the understanding of the microbial community composition of a breeding stock aimed to repopulate the EMS to improve its conservation status practically extinct in the area.
Nucleation-promoting and growth-limiting synthesis of disordered rock-salt Li-ion cathode materials
Authors: Lee Jinhyuk , Ahmed Hoda , Woo Moohyun , Dumaresq Nicolas , Lara Pablo , Brodusch Nicolas , Seo Dong-Hwa , Gauvin Raynald , Demopoulos George
Published: October 2024

Manganese-based disordered rock-salt (Mn-DRX) oxides and oxyfluorides are promising cathode materials for high-performance, nickel- and cobalt-free Li-ion batteries. However, existing synthesis methods for these materials require post-synthesis particle pulverization to achieve acceptable particle size for cycling, which lacks control over particle microstructure and crystallinity, accelerating performance degradation and limiting secondary particle processing. In this study, we propose a universal synthesis method using Li1.2Mn0.4Ti0.4O2 as a representative Mn-DRX, which promotes nucleation while limiting particle growth and agglomeration. This method controls the particle size while preserving the crystallinity to produce highly crystalline, dispersed sub-200 nm single particles, which form homogeneous electrode films with significantly improved capacity retention (84.3% over 100 cycles at ~200 mAh/g) and discharge voltage retention (4.8 mV loss per cycle) compared to electrodes made from particles synthesized through traditional solid-state synthesis followed by pulverization (38.1% capacity retention and 7.5 mV loss per cycle). Our approach offers a new direction for Mn-DRX research and development in nickel- and cobalt-free Li-ion batteries.
Analyzing the Impact of Different Shading Devices on Energy Consumption and Thermal Comfort in Office Buildings Using Machine Learning and Energy Simulation in Three Different Climates of Iran.
Authors: Abedini Mohammad Hassan
Published: October 2024

This study investigates the impact of three types of shading devices, including overhangs, louvers, and side fins, on energy consumption and thermal comfort in office buildings. The analysis utilizes climatic data from three cities—Yazd, Tehran, and Bandar Abbas—extracted from EPW files and simulated using the Honeybee and Ladybug tools. Additionally, the XGBoost machine learning model is employed to provide more accurate predictions of shading devices' effects on indoor temperature and energy consumption. Key climatic factors such as temperature, solar radiation, humidity, and wind speed are used as input variables for the model. The results indicate that overhangs in the hot and dry climate of Yazd significantly reduce energy consumption, while louvers demonstrate the highest efficiency in the hot and humid conditions of Bandar Abbas. This study highlights the importance of combining energy simulations with machine learning algorithms to optimize shading device design and improve thermal and lighting comfort.
Institutionalization of the party system in the de facto states of the post-soviet space (by the example of the Republic of Abkhazia)
Authors:   Institute of world economy and international relations Baikal State University, Shalak Alexander V. , Yeritsyan Inga N. ,   Institute of world economy and international relations Baikal State University
Published: October 2024

To ensure the democratic functioning of the state, the party system must be competitive and institutionalized, in connection with which it is relevant to study the process of institutionalization of the party system in the Republic of Abkhazia, which allows us to determine not only the stages of this process, but also a number of its features, including the degree of institutionalization . The novelty of the work: the reasons for the low level of institutionalization of parties and party systems in Abkhazia are identified. Object of study: the party system of the de facto states of the post-Soviet space. Subject: institutionalization of the party system in Abkhazia. The purpose of the work is to determine the features and main stages of the institutionalization of the party system in Abkhazia. Methodology and research methods: to analyze the process of institutionalization of the party system of Abkhazia, the organizational approach proposed in the works of M. Duverger and M. Ya. Ostrogorsky, which makes it possible to analyze the process of institutionalization of parties from the point of view of their organizational structure. The results of the research contribute to the scientific discussion about the role of political parties and the level of institutionalization of the party systems of Abkhazia and can serve as a basis for further study of the role of public associations and political parties in political processes, including in other de facto republics of the post-Soviet space. Conclusions: the programs of all parties are united in matters of the status of Abkhazia in the global political space, socio-economic development priorities and the preservation of the institution of the president; high informational activity of pro-government parties; The choice of the Abkhazian electorate is focused primarily on individuals, and not on ideology and the party program.
Prospects for the tourism development in the Russian Far East
Authors:   Far Eastern Federal University, Vladivostok, Davyborets Elena N. , Radikov Ivan V. ,   Saint Petersburg State University
Published: October 2024

The prospects for the tourism development in the Russian Far East should be considered in the context of numerous factors contributing to and hindering this direction. The object of the study is the tourism industry in Russia. The subject is the factors influencing the tourism development in the Russian Far East at the present stage. The purpose of the study is to analyze the numerous conditions for the tourism development in the Far East. The research methodology provides for a systematic approach to consider the tourism industry as an integral system, including numerous factors that have a direct and indirect impact on it. Research methods are as follows: general scientific methods are used – analysis, synthesis, induction, deduction, analogy, etc., which allows us to identify the factual side of the problem – the prospects for the development of tourism in the Far East, as well as to trace its development in dynamics, and make a forecast for the future. The method of comparative analysis has made it possible to identify the strengths and weaknesses of the resource component of the modern tourism industry in the region. The complex use of these and other methods allows us to recreate an objective and dynamic picture of the subject of research. Tourism is currently one of the most popular and profitable destinations in the global economy: both developed and developing countries are striving to occupy their niche in the tourism industry. Russia’s turn to the East forced us to pay special attention to it due to a number of favorable factors for its development: large recreational potential, high density and population of Asian neighbors, interest of domestic and foreign investors in the tourism business, etc. There are also problems faced by the tourism industry in the Far East: difficult weather conditions, insufficient funding, poorly developed infrastructure, flight distances, etc. It is concluded that the long-forgotten Russian Far East has all the necessary prerequisites for the development of domestic and foreign tourism on its territory.
Development of an Enlarged Adsorber for the Processing of Productive Solutions
Authors:   Research Geotechnological Center, Far Eastern Branch of Russian Academy of Sciences, Popov Grigory V. , Iodis Valentin A. ,   Research Geotechnological Center, Far Eastern Branch of Russian Academy of Sciences
Published: October 2024

Productive solutions obtained after leaching of ores have a complex composition, including a variety of non-ferrous and heavy metal cations. The method of extracting nickel from productive solutions after leaching of sulfide and lateritic ores is the most important process in hydrometallurgical processing. Sorption by ion-exchange resins is an alternative to existing technologies for nickel recovery from productive solutions. The ability to selectively extract nickel and regenerate makes polymeric ion-exchange resins one of the most popular sorbents in the modern world. The polymer resin sorption process avoids wastage of reagents, costly filtration, and poor nickel selectivity compared to other metal ions associated with solvent extraction processes. In order to conduct experimental studies of sorption using Amberlite IRC 748 polymer resin, it is necessary to calculate and design an adsorber. The objectives of the study include the determination of the geometric parameters of the adsorber, the parameters of the sorption/desorption process and the development of a process flow diagram. As a result of the research, an enlarged adsorber has been designed to extract nickel from the productive solution after bacterial-chemical oxidation of cobalt-copper-nickel sulfide ore, and a process flow diagram for the process of obtaining nickel salts from the productive solution has been developed. The volume of the adsorber, its height, diameter, diameter of the inlet fitting, the height of the sorbent layer, the required resin flow rate, and the duration of the process before regeneration are determined. To ensure the continuity of the process, taking into account the duration of bacterial-chemical oxidation, periodic regeneration of the sorbent, the number of adsorbers in a common installation is taken to be two. When the adsorption stage occurs in one of the apparatuses, the stage of regeneration and drying of the polymer resin proceeds in the other. The estimated sorption capacity of Amberlite IRC 748 resin was taken as 21.6 g of nickel per 0.1 kg of adsorbent. Resin desorption has been supposed to be carried out with a 10 % sulfuric acid solution, at a flow rate of 5 l/h.
Prospects for the Development of the Global Market for Shipping Liquefied Natural Gas
Authors:   St. Petersburg State Marine Technical University, Marchenko Sergey S.
Published: October 2024

This article explores the significance of future prospects for the development of maritime transportation of natural gas, which is one of the main sources of energy raw materials. Transportation of gas on sea vessels is expedient and cost-effective only in liquefied form, when the volume of natural gas is reduced by more than 600 times. Liquefied natural gas (LNG or LNG) carriers are called LNG carriers. The purpose of the study is to develop a new mathematical model that will play the role of a methodological basis for forecasting changes in the global volume of LNG shipping. In the course of the study, general scientific methods of system analysis and synthesis, methods of mathematical statistics were used. The article presents the results of the study of trends in the global maritime LNG transportation market development. The author considers the main exporters and importers of LNG, as well as an assessment of the growth in its demand after the decline of the COVID-19 pandemic. The trend in the development of innovative gas liquefaction production capacities, as well as the state of the world LNG fleet and the dynamics of its increase, are analyzed.The development research of this area of maritime transportation has been carried out and the dynamics of the increase in the volume of transported LNG in recent years has been analyzed.
Influence of a new controlled voltage regulator on the current and voltage non-sinusoidality of a power supply system
Authors: Tabarov B. D.
Published: October 2024

This work evaluates the influence of a new controlled voltage regulator on the current and voltage non-sinusoidality in different sections of a power supply system during smooth (discrete) voltage regulation on the high-voltage side of a shop transformer. The MatLab software application was used to develop a block-modular model for a transformer substation with the proposed controlled voltage regulator and measurement modules. The developed model was used to investigate the current and voltage non-sinusoidality in different parts of a power supply system when stabilizing the voltage at the consumer end at a given level. The study was carried out using a shop transformer with a capacity of 1 MV∙A and a voltage of 6/0.4 kV under an active-inductive character of the load with the load current phase angle of φ=45 deg. The obtained results confirm that, due to the extended functional capabilities of the proposed technical solution, the voltage at consumers is maintained at a given level under high technical and economic performance. When the network voltage is reduced by 5% and the activeinductive load current is increased by 35%, the proposed device was shown to create voltage non-sinusoidality. The voltage non-sinusoidality value does not exceed the permissible domestic and international norms. In addition, the proposed device is capable of maintaining the voltage at the consumer end at a given level. The obtained integral characteristic of voltage stabilization shows that the application of the proposed technical solution instead of the existing mechanical voltage regulator of the “switching without excitation” type allows the nominal voltage at the busbar of the switchgear to be retained. Further research will investigate voltage stabilization at consumers with simultaneous compensation of reactive power for complex improvement of technical and economic indicators of power supply systems under the conditions of unstable supply voltage and load current.
Kinetic characteristics of bornite and chalcopyrite dissolution in nitric acid
Authors: Shklyaev Yu. , Dizer O. A. , Lugovitskaya T. N. , Golovkin D. I. , Rogozhnikov D. A.
Published: October 2024

The kinetic characteristics of dissolution of copper-bearing sulfides – chalcopyrite (CuFeS₂) and bornite (Cu₅FeS₄) – in nitric acid were studied. The kinetics of the dissolution process was described using a compressible nucleus model. Chalcopyrite of the Vorontsovskoye deposit and bornite of the Karabash deposit were used as research objects. Solution and cake samples were analyzed by optical emission spectrometry and X-ray fluorescence analysis, respectively. The results obtained were processed in the MS Excel software package. The influence of various factors, including temperature, solvent concentration, particle size, and process duration on the dissolution degree of minerals was studied. The process parameters were varied as follows: temperature – from 35 to 95°C; HNO₃ concentration – from 1 to 9 mol/dm³; particle size – from +0.1 to 0.056 mm; duration – from 0 to 60 min. It was established that an increase in temperature and acid concentration leads to a significant increase in the degree of dissolution of both chalcopyrite and bornite. A decrease in particle size also contributes to a more efficient dissolution of both minerals in nitric acid. The calculated activation energy values were 55 kJ/mol for chalcopyrite and 43 kJ/mol for bornite, which is characteristic of the kinetic region of the process. The reaction orders in terms of reactant were determined: 1.62 for chalcopyrite and 1.57 for bornite. In terms of particle size, these were -1.16 for chalcopyrite and -2.53 for bornite. On this basis, generalized equations of dissolution kinetics for both minerals were derived. The results obtained allow an assumption about the kinetic nature of dissolution of chalcopyrite and bornite under the studied conditions.
Sistem Pendukung Keputusan Berbasis K-Means untuk Evaluasi Keberhasilan Bisnis dan Nilai Perusahaan
Authors: Sarmini Sarmini , Ma'arifah Windiya , Tahyudin Imam
Published: October 2024

Business development is in line with the development of increasingly sophisticated technology. This requires every company to compete and be motivated to increase its value as an indicator of success in managing the company so that investors are interested in investing. This study aims to design a K-means-based Decision Support System with a clustering approach to classify the growth rate of company value. Investment Opportunity Set (IOS) and profitability variables are the leading indicators of increasing company value. The problem formulation is how the design of this K-means-based decision support system can assist in classifying the growth rate of the company's value based on the IOS and profitability variables. This research aims to produce a decision support system that can organize the growth rate of company value using the K-means method. System testing is conducted to evaluate the effectiveness of the applied clustering method, focusing on the accuracy of the results. The weighting of IOS and profitability variables is based on the percentage of positive relationship to firm value, and the ultimate goal is to group companies with different growth rates. As a result, the K-means-based Decision Support System, or "Business Growth Prediction Decision Support System," successfully clustered the growth rate of firm value. With reasonable accuracy, measured using the silhouette coefficient, the calculation results show an overall mean silhouette coefficient of 0.684, close to the maximum value of 1. This result confirms that this decision support system can group companies in the L (Low), M (Medium), and H (High) categories based on the level of value growth, using the IOS and profitability variables as the leading indicators. Thus, this research supports decisions related to company growth strategies using K-means-based decision support systems.
Pengukuran Tingkat Risiko dan Keamanan Informasi Menggunakan Metode FMEA Berbasis ISO/IEC 27001 pada Instansi XYZ untuk Keamanan Sistem Informasi
Authors: Kusnandar Aris , Rochim Adian Fatchur , Gunawan Vincensius
Published: October 2024

The more information stored in an organization, the higher the risks that may arise, such as damage, loss, or the exposure of personal information to irresponsible parties. XYZ Institution faces information security threats from various sources, including data theft, damage, and computer hacking. It is essential for the organization to understand the level of information security risk to ensure information remains secure. Therefore, this study proposes measuring information security risk using the FMEA method and analyzing information security risks based on ISO/IEC 27001:2013. The aim of this study is to identify and assess the level of information security risk at XYZ Institution to provide recommendations for information security. The study's results revealed 4 high-risk information security threats, 9 medium-risk threats, and 16 low-risk threats. The findings demonstrate that the organization needs to pay more attention to information security to ensure its smooth operation in the future.
The New European Bauhaus: The ‘Simplexity’ of Innovation in Design
Authors: Rotondi Carmen
Published: October 2024

European initiatives, such as the New European Bauhaus, foster collaboration across diverse sectors, artistic experimentation and new materials, creating a movement that inspires and guides the transition to a fairer and resilient future for the Next Generation. In this regard, design needs to experiment with a cultural and interdisciplinary implementation of approaches for serving as a bridge between disciplines and between technology and sustainability, ensuring that ethical and sustainable principles guide digital and scientific innovation. The paper presents "Biovision of the future", an educational and research experience conducted at the Saperi&Co research and service centre of Sapienza University of Rome on the issues of Bio Revolution and aimed to experiment with new hybrid processes and methodologies as fertile ground for converging different knowledge and perspectives on complex issues and to foster a more critical and strategic design culture regarding using advanced (bio)technologies. These methodologies, accomplished during a workshop phase and built on a strong interaction and hybridisation between the design methodologies (inductive-experiential-synthetical) and the scientific, sociological and psychological methodologies (deductive-logical-analytical), use visual tools to stimulate interdisciplinarity, critical thinking and strategic reflection during participatory dialogues and co-design activities. The results materialised in six design concepts as forward-looking strategies and solutions (products, processes, services, systems) to "rebuild" the lost links between humans and nature, technology and ecology, fostering Biorevolution from an ethical perspective. They prove the importance of employing systemic and lateral thinking, proactive and future-oriented approaches capable of managing a wide range of information, enabling the planning of actions, and making informed decisions. In this sense, implementing visual methods in design processes becomes central and proactive, materialising complex meanings in 'signs' and using a simple and universal language suitable for organising non-linear processes and 'simplexity'.
Head Games: Exploring the Symbolic Uses of Heads in Fashion Shows
Authors: Domínguez Mariel , Aman Hoda Mohamed
Published: October 2024

The study explores the symbolic uses of heads in fashion shows, multifarious influence and the cultural/historical symbolism that it holds against a multiplicity of representations, sites, and registers: religion, art, fashion. In following the evolution of uses of heads from its birth as a dread form of punishment and tool of terror to implications and representations by media and consumer culture in today's society, the research applies an in-depth analytical approach. The transformation of this motif and the influence on societal norms and values turned toward this motif in the respective historical periods and cultural contexts have been methodically analyzed. Illustrating that while decapitation has forever provoked a reaction from revulsion to fascination, these days it is rebooted as a provocative symbol in fashion and art, often straying between cultural tribute and tastelessness. An example of this research is the study that seeks to describe cases whereby fashion brands like Gucci and Balenciaga were using images of beheading in a bid to illustrate the thin line between creative freedom and cultural appropriation. A sensitive approach needs to be paid to the use of such potent symbols, which includes the possibility of respect or offense, depending on the context of use. This makes the study relevant in its contribution of understanding how re-interpretations of historical symbols are done in contemporary culture and, respectively, the influence they have on issues of identity and ethics in the strategy of global marketing. This study extended the academic debate about the cultural symbolism by providing useful insight to practice by brands on how to manage the perils cultural representation may pose in a global market.
Machine Learning for Basic Visual Research in Graphic Design
Authors: Raff Jan-Henning
Published: October 2024

This paper explores the intersection of machine learning and graphic design, aiming to enhance visual analysis methodologies through the integration of domain-specific knowledge. A critical examination of existing machine learning approaches for visual analysis reveals their limitations and the need to integrate more design specific knowledge. The paper proposes two approaches to analyze spatial aspects of graphic design. The application of the proposed methods demonstrates the potential of machine learning to reconstruct the intuition of graphic designers and to automate visual analysis tasks. The relevance of this study lies in its contribution to both academic research and practical applications in graphic design. By bridging the gap between computational methods and design theory, the study offers new perspectives on visual communication and provides tools for designers and researchers alike. Moving forward, interdisciplinary collaborations between machine learning experts and graphic designers will be essential to refine methodologies and unlock the full potential of machine learning in visual communication.
Demystifying Art Therapy: Using Response Art to Enhance Reflexivity, Professional Knowledge, and Collegiality in a Grounded Theory Methodology Design
Authors: Theodoropoulou Dimitra
Published: October 2024

This paper is part of a professional doctorate research in Health and Social Care aiming to advance practice-based knowledge of Art Therapy. The literature review highlighted the need for more qualitative research with children addressing the question ‘how Art Therapy works’. The study was conducted within a children’s mental health charity in the UK exploring conceptualisation of change through the Art Therapists’ perspectives. The overarching methodology used was Constructivist Grounded Theory including the methods of Intensive Interviewing and Response Art. Five Art Therapists were interviewed twice to allow for deeper exploration of case studies. Researcher and participants created response art images between the interviews to visually reflect and capture symbolic nuances of change in the children’s journey. Presented in the findings are the author’s response art images, accompanied by selected excerpts of shared reflections with and from the participants illustrating the process of visual exploration. The discussion lays out the author’s insight into the benefits of the researcher sharing their own Response Art with the participants for bringing about collegial vulnerability and collaboration. The conclusion is focused on how visual reflexivity methods, such as response art, can create conditions of time, space and hope in stimulating research and advancing professional knowledge.
Exploring Visual Analysis in Design Research: Insights from Workshops with PhD Students at the University of Porto, 2022
Authors: Barreto Susana , Alvelos Heitor , Rebelo Ana Miriam , Lopes Luciana
Published: October 2024

This paper discusses two workshops on visual analysis conducted with research students from the PhD in Design at the University of Porto in 2022 within a curricular context. The objectives were to extract significance from visual information and to use visual methods for more effective research communication. The workshops focused on visual ethnographic analysis of photographs. Through hands-on exercises and joint theorising, two doctoral projects gained insights. The first project aimed to explore the contributions of informal dwelling to the city of Porto's visual and semantic identities using visual ethnography. The workshop's goal was to refine the research universe's definition. The second project, ‘Pulse Approach’, proposed a design project management tool based on ancestral wisdom from Portugal and Brazil's southern communities. The workshop aimed to clarify the research concept and facilitate an exploratory immersion for the transformative social design concept. In both workshops, clusters of images were analysed to identify themes, patterns, and connections. Visual methods allowed researchers to engage better with participants, validating their self-expression through selected photographs. Visual data brought participants' experiences and perspectives to life for analysis and interpretation, providing multidimensional feedback as triggers of memories and feelings. The workshops provided insights into collaboration and interdisciplinary approaches in design research, demonstrating the potential of visual methods for supporting research outcomes. Working with students from different disciplines brought diverse perspectives and insights. In the first workshop, colleagues helped interpret samples from the photographic collection, contributing to a suitable selection for analysis and communication. The process refined typological classifications, leading to a central definition for the research object. The second workshop, a collaborative work of sensorial and exploratory immersion, identified core concepts and terminologies from research images collected through fieldwork, based on feelings, impressions, and perceptions expressed by the focus group. It clarified the meaning of the concept and proposed a taxonomy of approaches to project management templates. Both workshops confirmed that a collective, exploratory use of visual methods for research analysis and communication enhances data, leading to new knowledge and tangible outcomes for research projects.
TO ASSESS THE EFFECTIVENESS OF VIDEO ASSISTED TEACHING PROGRAMME ON KNOWLEDGE REGARDING IMPORTANCE OF UMBILICAL CORD BLOOD PRESERVATION FOR FUTURE TREATMENT MODALITIES AMONG EXPECTANT COUPLES AT SELECTED HOSPITALS
Authors:   Asst. Professor, Swami Vivekanand Subharti University, Meerut., P.N Manikanadan , Unnikrishnan Arun ,   Associate, Professor, Swami Vivekanand Subharti University, Meerut., Malik Kavita ,   Asst. Lecturer, Swami Vivekanand Subharti University, Meerut.
Published: October 2024

Health is the general condition of a person in all aspects it is also a level of functional and metabolic efficiency of an organism. Nothing is more important than protecting the health of your family. A healthy future starts with saving - or banking - your newborns cord blood stem cells. Its a one-time opportunity that can change or even save a life. After a baby is delivered, the mothers body releases the placenta, the temporary organ that transferred oxygen and nutrients to the baby while in the mothers uterus. Stem cell research holds enormous promise for easing human suffering. We have a lot to gain through furthering stem cell research, but medical breakthroughs should be fundamentally about saving, not destroying, human life. Therefore, support stem cell research that does not destroy the embryo. The aim of this study is to assess the effectiveness of video assisted teaching programme on knowledge regarding importance of umbilical cord blood preservation for future treatment modalities among expectant couples. The main objective of the study was to assess the knowledge regarding importance of umbilical cord blood preservation for future treatment modalities among expectant couples. Methodology: The sample size was 60 expectant couples and the setting of the study was selected hospitals where the couples come for antenatal checkup. Sampling technique was convenient sampling technique. One group pretest posttest design was used. Result: The study shows that in pre-test 81.67% of couples were having inadequate knowledge and 18.33% of them having moderately adequate knowledge and none of them having adequate knowledge. While in post test 55% of expectant couples were having Moderately Adequate knowledge and 45% of them having adequate knowledge and none of them having inadequate knowledge. The result shows that the video assisted teaching was effective in improving the knowledge. There was significant association between selected demographic variables and post test score. Conclusion: The teaching was effective in increasing the knowledge of expectant couples and similar awareness programmes should be given to the public so that they can understand regarding the newer treatment modalities.
SMILE REHABILITATION IN ANTERIOR AESTHETIC ZONE USING BASAL IMPLANT
Authors: Khadse Apurva , Thombre Vivek , Phadnaik Mangesh , Bhesaniya Vivek , Nagdeve Ayushi , Gawande Dipak
Published: October 2024

Aesthetics are one of the primary goals of restorative care. Teeth that are traumatized in the anterior maxilla usually avulse or require extraction due to fractures. Rehabilitation is challenging in such a therapeutic state since it presents several anatomical and aesthetic issues. There are circumstances in which traditional implant placement is problematic. There must be enough bone for implant placement to be uneventful and successful. Other surgical therapies may be necessary in addition to implant placement for certain operations, such as extensive grafting, direct or indirect sinus lifts, and nerve lateralization. Certain procedures are required for these operations but are not always achievable. Because single-piece basal implants provide immediate temporization and loading while receiving adequate anchoring from the basal cortical bone, they have been extensively used to rehabilitate resorbed ridges. This case report demonstrates the placement of the basal implant in the anterior zone.
THE AI-GENDER INTERSECTION: PIONEERING SOLUTIONS FOR WORK-LIFE BALANCE BEYOND TRADITIONAL HOURS
Authors: Kohli Kamya
Published: October 2024

The paper explores the intersection of artificial intelligence (AI) and gender equality, focusing on how AI can address gender disparities in the workplace and enhance work-life balance. It begins by outlining the historical context of the traditional 9-5 work model and its implications for gender inequality, particularly the challenges faced by women in achieving career advancement and work-life balance. The research objectives include investigating the potential of AI technologies to reduce gender disparities, improve work-life balance, and foster unbiased hiring practices. Key findings highlight that AI can play a pivotal role in transforming workplace dynamics by automating repetitive tasks, enabling flexible work arrangements, and providing personalized support for employees. Case studies illustrate successful implementations of AI in recruitment processes, showing how organizations like Unilever and Hilton have utilized AI to promote fairer hiring practices and enhance diversity. However, the paper also addresses the risks of AI reinforcing existing biases if not carefully managed. The significance of this research lies in its implications for policymakers, employers, and workers. By leveraging AI responsibly, organizations can create more equitable workplaces that accommodate diverse needs and promote gender parity. The paper concludes with recommendations for ethical AI use, emphasizing the importance of transparency, accountability, and continuous monitoring to mitigate biases and ensure that AI technologies benefit all employees.