bluuebunny/crossref_metadata_2025 huggingface dataset:
Mobile-Based Self-Care Application for COVID-19: Development Process Using the ADDIE Model
Authors: Saeidnia Hamid Reza , Ausloos Marcel , Mohammadzadeh Zahra , Babajani Afshin , Hassanzadhh Mohammad
Published: January 2022

During the COVID-19 era, technology-enhanced protection of this disease has saved lives in developed countries in which citizens have the privilege of accessing and using such technologies to fight Coronavirus. In the undeveloped countries, on the other hand, citizens have had no accession or ability to use digital technologies to prevent COVID-19. Having this in front, in the MyShield research project, we aim to address how to teach self-care skills in undeveloped countries in the era of COVID-19 using a mobile low-cost application effectively based on a standard educational model (ADDIE). This paper reports a framework that arises from the results of semi-structured interviews and online workshops conducted in the ADDIE design process for the self-care mobile application. The specialists contributed to indicte the appropriate content for teaching self-care skills while informants contributed to optimize the user experience flow.
Minimization of the Drug and Gene Interactions in Polypharmacy Therapies Augmented with COVID-19 Medications
Authors: Lagumdzija-Kulenovic Azra , Kulenovic Adnan
Published: January 2022

Medications Dexamethasone, Remdesivir or Colchicine, used to treat COVID-19 patients, have significant interactions with other medications and the human genome. The study presented in this paper investigates how to use the Personalized Medicine Therapy Optimization Method (PM-TOM) to minimize these interactions in polypharmacy therapies of COVID-19 patients. We applied PM-TOM on the EMR database of Harvard Personal Genome Project (PGP), drug database DrugBank and Comprehensive Toxicogenomics Database (CTD) to analyze polypharmacy therapies augmented with these medications. The main finding is that these COVID-19 medications significantly increase the drug and gene interactions in partially optimized (or unoptimized) therapies, which is not the case in the fully optimized ones. For example, the test results show that in polypharmacy treatments for patients having between 3 and 8 conditions, the average number of drug and gene interactions in partially optimized therapies ranges from 3 to 18 after adding Remdesivir, 4.3 to 20 Colchicine, and 4.7 to 23 Dexamethasone. On the other hand, these interactions in fully optimized therapies range only 0.6 to 5.2, 1.2 to 7, and 2.7 to 11, respectively. These results suggest that polypharmacy therapies should be carefully examined before adding these medications. This recommendation applies to all other situations when polypharmacy patients may conduct new serious conditions, such as COVID-19, requiring additional medications with a high number of drug and gene interactions.
Development and Evaluation of a Bayesian Risk Stratification Method for Major Amputations in Patients with Diabetic Foot Ulcers
Authors: Hüsers Jens , Hafer Guido , Heggemann Jan , Wiemeyer Stefan , John Swen Malte , Hübner Ursula
Published: January 2022

The diabetic foot ulcer, which 2% – 6% of diabetes patients experience, is a severe health threat. It is closely linked to the risk of lower extremity amputation (LEA). When a DFU is present, the chief imperative is to initiate tertiary preventive actions to avoid amputation. In this light, clinical decision support systems (CDSS) can guide clinicians to identify DFU patients early. In this study, the PEDIS classification and a Bayesian logistic regression model are utilised to develop and evaluate a decision method for patient stratification. Therefore, we conducted a Bayesian cutpoint analysis. The CDSS revealed an optimal cutpoint for the amputation risk of 0.28. Sensitivity and specificity were 0.83 and 0.66. These results show that although the specificity is low, the decision method includes most actual patients at risk, which is a desirable feature in monitoring patients at risk for major amputation. This study shows that the PEDIS classification promises to provide a valid basis for a DFU risk stratification in CDSS.
The Linkage Between Bone Densitometry and Cardiovascular Disease
Authors: Refaee Mahmoud A. , Al-Absi Hamada R.H. , Islam Mohammad Tariqul , Househ Mowafa , Shah Zubair , Rahman M.Sohel , Alam Tanvir
Published: January 2022

Dual-energy X-ray absorptiometry (DXA) has been traditionally used to assess body composition covering bone, fat and muscle content. Cardiovascular disease (CVD) has deleterious effects on bone health and fat composition. Therefore, early detection of bone health, fat and muscle composition would help to anticipate a proper diagnosis and treatment plan for CVD patients. In this study, we leveraged machine learning (ML)-based models to predict CVD using DXA, demonstrating that it can be considered an innovative approach for early detection of CVD. We leveraged state-of-the-art ML models to classify the CVD group from non-CVD group. The proposed logistic regression-based model achieved nearly 80% accuracy. Overall, the bone mineral density, fat content, muscle mass and bone surface area measurements were elevated in the CVD group compared to non-CVD group. Ablation study revealed a more successful discriminatory power of fat content and bone mineral density than muscle mass and bone areas. To the best of our knowledge, this work is the first ML model to reveal the association between DXA measurements and CVD in the Qatari population. We believe this study will open new avenues of introducing DXA in creating the diagnosis and treatment plan of cardiovascular diseases.
Recent Developments in Artificial Intelligence-Based Techniques for Prostate Cancer Detection: A Scoping Review
Authors: Shah Uzair , Biswas Md. Rafuil , Alzubaidi Mahmood Saleh , Ali Hazrat , Alam Tanvir , Househ Mowafa , Shah Zubair
Published: January 2022

Artificial intelligence (AI) techniques can contribute to the early diagnosis of prostate cancer. Recently, there has been a sharp increase in the literature on AI techniques for prostate cancer diagnosis. This review article presents a summary of the AI methods that detect and diagnose prostate cancer using different medical imaging modalities. Following the PRISMA-ScR principle, this review covers 69 studies selected from 1441 searched papers published in the last three years. The application of AI methods reported in these articles can be divided into three broad categories: diagnosis, grading, and segmentation of tissues that have prostate cancer. Most of the AI methods leveraged convolutional neural networks (CNNs) due to their ability to extract complex features. Some studies also reported traditional machine learning methods, such as support vector machines (SVM), decision trees for classification, LASSO, and Ridge regression methods for features extraction. We believe that the implementation of AI-based tools will support clinicians to provide better diagnosis plans for prostate cancer.
Evaluative Frameworks and Models for Health Information Systems (HIS) and Health Information Technologies (HIT)
Authors: Joseph Amanda L. , Stringer Eleah , Borycki Elizabeth M. , Kushniruk Andre W.
Published: January 2022

Evaluation criteria for health information systems (HIS) and health information technologies (HIT) is broad, diverse and lacks a gold standard approach that could be leveraged, to evaluate clinical systems at various stages of their system development life cycle (SDLC). Without generalizable tools such as frameworks or models, comparative analysis across HIS and HIT is not possible. This paper presents the findings from a scoping review, utilizing the Arksey and O’Malley methodology [1]. The objective of this review is two-fold: 1) to classify models and frameworks published between the years 2010–2020 according to their level of evaluative focus (e.g. micro, meso, macro, multi), 2) to identify the countries where these models and frameworks have been employed for the purpose of evaluation, using the International Medical Informatics Association (IMIA) Represented Regions [3]. The results demonstrated the heterogeneity of evaluation models and frameworks currently used in health informatics and reflected the necessity for more adaptive approaches to HIS and HIT evaluation.
Digital Health Platform for Emotional and Self-Management Support of Caregivers of Children Receiving Growth Hormone Treatment
Authors: Signorelli Gabriel , Núñez-Benjumea Francisco José , Muñoz Antonio De Arriba , Callau Marta Vara , Pierantonelli Maitena , Jiménez- Díaz Alba , Fernandez-Luque Luis
Published: January 2022

In recent years there has been growing research on the combination of evidence-based behavioral change techniques with mobile-based recommender systems. In this paper, we have focused on understanding the psychological burdens experienced by caregivers of children undergoing growth hormone treatment (GHt) and the perceived barriers to and drivers of the adoption of a digital health solution. This is a mixed-methods formative research study looking into technical acceptance aspects of using digital health for the emotional support of parents of children undergoing GHt. After one month using the ADHERA CARING platform (Adhera Health, Inc., Palo Alto, CA), individual semi-structured interviews were conducted. ADHERA CARING provides tailored emotional and self-management support to caregivers of children undergoing GHt to improve adherence to treatment through positive education, personalized motivational messages, and emotional support. A preliminary thematic analysis and categorization were carried out, based on the Behavioral Intervention Technology (BIT) model. The majority of participants were female. All caregivers positively valued having the tool, especially at the beginning of treatment. Information provided in the educational module was useful and improved self-efficacy. Motivational messages contributed to commitment and reinforced the educational content, thus promoting continuity of treatment and potentially improving treatment efficacy. Most participants (n=10, 80%) accessed all educational units and completed all the 27 quiz questions. Regarding the motivational messages, the overall average rating was 4.55 out of 5.00. ADHERA CARING has the potential to help caregivers to understand the treatment journey. Nevertheless, users have identified that some types of educational content are more valuable at specific stages of the treatment journey, which suggests that personalization of educational content is required to adapt to different stages of the patient journey.
Assessing Staff’s and Stroke Patients’ Experiences in 8 Hospitals in Greece: Results from a Prospective Multi-Center Study (“SUN4Patients”)
Authors: Galanis Petros , Konstantakopoulou Olympia , Karagkouni Iliana , Gallos Paris , Tsampalas Evangelos , Lypiridou Maria , Gamvroula Anastasia , Mavraganis Georgios , Manios Efstathios , Ntaios George , Karagkiozi Efstathia , Milionis Haralampos , Evangelou Chara , Tountopoulou Argyro , Kouzi Ioanna , Vassilopoulou Sofia , Protogerou Athanasios , Samara Stamatina , Karapiperi Asteria , Savopoulos Christos , Hatzitolios Apostolos I. , Myrou Athina , Kalliontzakis Ioannis , Kouridaki Aspasia , Papastefanatos Stefanos , Papastefanatos George , Vemmos Kostas , Sourtzi Panayiota , Bellali Thalia , Korompoki Eleni , Kaitelidou Daphne , Siskou Olga
Published: January 2022

To assess stroke patient-reported experiences and hospital staff experiences, during hospital stay. Methods: Stroke patient-reported experiences (n=387) were recorded using the translated and culturally adapted NHS-Stroke Questionnaire into Greek and staff experiences (n=236) were investigated using the Compassion Satisfaction and Burnout subscales of the ProQOL questionnaire. Results: Staff’s mean compassion satisfaction score was 39.2 (SD=6.3) and mean burnout score was 24.3 (SD=5.6). Only 38.5% of the staff stated that there is smooth cooperation with healthcare professionals of other specialties/disciplines. Personnel working in an NHS Hospital was more satisfied and less burned-out when compared to personnel working at a University Hospital (p=0.02 and p<0.001, respectively). Mean total patient-reported experiences score was 81.9 (SD=9.5). Bivariate analysis revealed statistically significant differences for total patient-reported experiences among the eight study hospitals (p>0.001). Conclusions: Health policy planners and decision-makers must take into consideration the results of such self-reported measures to establish innovative techniques to accomplish goals such as staff-specialization, continuous training and applying formal frameworks for efficient cooperation amongst different disciplines.
Using Automated Text Processing to Assess the Patient Experience of an On-Demand Tele-Urgent Care
Authors: Khairat Saif , Zhang Xinyi , Boyd Makena , Edson Barbara , Gianforcaro Robert
Published: January 2022

Novel methods are needed to evaluate the perceptions of patients using telehealth. Automated text processing methods presents a golden opportunity to classify and analyze unstructured survey responses from patients. This study analyzed 585 unstructured entries from telehealth patients. Satisfied patients who returned for a second visit applauded the efficiency and physician interactions. While unsatisfied patients who did not return for a second visit complained of misdiagnosis and inefficiencies in e-prescription. Patient experience was significantly different between weekdays and weekends (p<0.05). Overall, tele-urgent are convenient for patients however, there are current facilitators related to patient-provider interaction and health information exchange that need further optimization.
Electronic Health Records and Physician Burnout: A Scoping Review
Authors: Muhiyaddin Raghad , Elfadl Asma , Mohamed Ebtehag , Shah Zubair , Alam Tanvir , Abd-Alrazaq Alaa , Househ Mowafa
Published: January 2022

This scoping review aims to identify the causes and consequences of physician burnout resulting from using Electronic Health Records (EHRs), as reported by current literature. We identified studies by searching PubMed, Wiley Online Library, and Google Scholar. Study selection and data extraction were conducted by three reviewers independently. Extracted data was then synthesized narratively. Out of 500 references retrieved, 30 studies met all eligibility criteria. We identified six main causes that lead to physician burnout related to the use of EHRs: EHRs’ documentation and related tasks, EHRs’ poor design, workload, overtime work, inbox alerts, and alert fatigue. We also identified the following consequences of physician burnout: low-quality care, behavioral issues, mental health complications, substance abuse, career dissatisfaction, costly turnover, and a decline in patient safety and satisfaction.
WITHDRAWN
Authors: Doe Jane
Published: January 2022

The document associated with this DOI has been withdrawn.
STUDY OF OUTCOME OF STATIN THERAPY IN PATIENTS BY CHECKING LIPID PROFILE AFTER 3 MONTHS OF STARTING TREATMENT IN STATIN NAIVE PATIENTS
Authors: Atwal Shilpa , Thakur Jitender
Published: January 2022

Background: To describe the outcome of statin therapy in patients by checking lipid profile after 3 months of starting treatment in statin naive patients

Methods: Study was conducted on Patients with indications for statins presenting to cardiology OPD, Medicine OPD and Endocrinology OPD and started on statins at PGIMER, Chandigarh, within a period of 9 months.

Results: The mean decrease in total cholesterol, triglycerides, VLDL and LDL levels in primary prevention group mean decrease in after 3 months of statin treatment in comparison to baseline were 17.24%,21.24%, 22.83 % and 33.19% respectively and increase in mean HDL level was 9.55%. The mean decrease in total cholesterol, triglyceride, VLDL and LDL levels in secondary prevention group after 3 months of statin treatment in comparison to baseline were 14.35% 15.80%, 16.17% and 36.92% respectively and increase in mean HDL level was 8.77%.

Concluded: So there was statistically significant change in lipid profile from baseline in both primary and secondary prevention groups after 3 months of statin treatment.

Keywords: Statin, LDL,VLDL, HDL
Effect of food additive E415 on the microstructure of rat liver
Authors: Ziruk I. V. , Rysmukhambetova G. E. , Beloglazova K. E. , Kopchekchi M. E. , Tarasova A. A.
Published: January 2022

One of the forms of activity of a veterinary specialist can be his work in a laboratory. Currently, there is an increasing need for laboratory studies of organs for their detailed study, as well as identification of pathologies. In this connection, there is a need for a more detailed study of the internal organs. The presented materials set out the results of a study of the effect of the food additive E415 on the morphology of the liver of rats. The work proved that the studied food additive does not have a negative effect on the organism of laboratory animals.
Oil flax – food culture (review)
Authors: Kosykh L. A.
Published: January 2022

Flax is an agricultural crop for complex use; it is widely used in textile, paint and varnish, electrical, rubber, leather, pharmaceutical, soap-making, as well as food and other industries. The interest in using flax as a food product is explained by its component structure. Flax seeds contain 25–48% oil and up to 30% protein, they also contain nitrogen – up to 5%, ash – up to 4%, fiber – up to 4.5%. Linseed oil contains up to 16–20% oleic fatty acid, 50–60% linolenic acid, 14–17% linoleic acid, 5–7% palmitic acid, 3–4% stearic acid. Recent studies have revealed the amazing healing properties of flaxseed oil, due to the presence of a large amount of linolenic acid in it. Unsaturated fatty acids accelerate the metabolism of cholesterol in the blood and promote its elimination from the body, improve the metabolism of proteins and fats, have a beneficial effect on blood pressure, relieve spasms of blood vessels and prevent the formation of blood clots and tumors. Flaxseed oil significantly reduces the risk of cardiovascular and cancer diseases, allergic reactions. Whole flaxseed does not lose its nutritional qualities for 3 years and is widely used in various countries of the world as popular additive to various types of bread and cereal mixtures, for sprinkling confectionery products. The flour obtained from fat-free seeds is used in various mixtures for baking bread and pastry.
Atuação fisioterapêutica no mal de Alzheimer: uma revisão da literatura
Authors: Oliveira Tâmara Lourdes da Silva
Published: January 2022

Restaurar funções como equilíbrio, força e coordenação motora, são alguns dos benefícios que a fisioterapia traz para o idoso, principalmente para aqueles que já possuem algum quadro patológico em curso. Geralmente estas doenças causam um déficit nas funções básicas, como na locomoção e coordenação motora. A doença de Alzheimer, em estágios mais avançados, deixa o idoso debilitado, acamado e com várias disfunções, como por exemplo: dificuldade para deambular normalmente. Portanto, a fisioterapia atua de modo a evitar e/ou retardar as adversidades causadas pela doença de Alzheimer. O objetivo do estudo foi verificar por meio da literatura a atuação fisioterapêutica no mal de Alzheimer. Para isto, adotou-se como metodologia a revisão da literatura, construída por meio de consulta às bases de dados e outros trabalhos relacionados ao tema, nos meses de julho de 2020 a outubro de 2021, respondendo à questão norteadora: Quais as condutas fisioterapêuticas descritas na literatura para os pacientes com doença de Alzheimer? Foram selecionados 13 trabalhos que explicitaram a importância da fisioterapia diante do tema exposto, sendo pontuada sua atuação no início da doença, desde a educação em saúde e orientações aos familiares. Pode-se concluir que, a atuação fisioterapêutica no mal de Alzheimer é benéfica aos pacientes portadores da afecção neurodegenerativa, não só do ponto de vista físico e motor, mas, também, cognitivo e respiratório, e que esta possui meios para reabilitar e retardar perdas funcionais, evitar encurtamentos musculares, promover a independência funcional, melhorando assim a qualidade de vida.
O paradigma do pastorado feminino na igreja evangélica da atualidade
Authors: Sá Danielle Mendonça de , Ghedini Robson Maurício
Published: January 2022

Atualmente, há igrejas que optam por limitar a contribuição da mulher no exercício de seu ministério em alguns setores eclesiásticos, ou mesmo, por silenciá-la. Portanto, essa pesquisa se pauta na seguinte questão: de que forma a análise do papel da mulher no contexto bíblico, auxilia na aceitação da legitimidade do pastorado feminino na igreja evangélica da atualidade? Assim, objetiva-se neste estudo proporcionar um novo horizonte na compreensão do tema da liderança eclesiástica feminina, de modo a contribuir com o solucionamento desta problemática e com a quebra de paradigmas, à luz da Bíblia Sagrada, descrevendo as principais dificuldades enfrentadas pela mulher no exercício ministerial, ao passo em que busca compreender o pensamento oriundo de aspectos do contexto social, político, histórico, econômico e religioso da época em que os textos bíblicos foram escritos. Para tanto, utilizou-se como pressuposto metodológico a pesquisa bibliográfica e a abordagem qualitativa de forma descritiva, pois, fez-se necessário apresentar elementos e fatos extraídos da história referentes a estes aspectos, visto que, a junção de todos, possibilitou traduzir o modo como os homens e as mulheres daquela época se portavam, pensavam e sentiam. Compreende-se, ainda, que esse pensamento impregnou a tradição da Igreja, ao longo dos séculos, no entanto, ressalta-se que a tradição cultural da época, não possui os mesmos elementos socioculturais da atualidade. Nesse sentido, são reunidas informações sobre as dificuldades enfrentadas pelas mulheres no campo social e religioso, a função feminina no judaísmo, sua participação no Cristianismo, desde o modo como Jesus as tratava; à participação delas na Igreja Primitiva, além de oferecer espaço de análise de textos bíblicos que lançam luz sobre a visão bíblica dos ministérios femininos, um relato sobre a história de Débora, uma pastora na prática, apesar de não ostentar o título, bem como, aborda-se sobre o ministério pastoral como um dom concedido por Deus. Conclui-se então que na atualidade conclama-se por mais mulheres destemidas, corajosas, fiéis a Deus, piedosas, obedientes, leais, pastoras de almas, como Débora, Miriã, Hulda entre outras. Afinal para homens e mulheres há um só Deus, uma só missão (a Dele), uma só visão e um só alvo, Jesus.
Comparison of efficiency of diesel fuel fractions recovery at stages of atmospheric and vacuum oil distillation
Authors:   SLAVNEFT-YANOS PJSC, Yaroslavl, Karpov N. V. , Vakhromov N. N. ,   SLAVNEFT-YANOS PJSC, Yaroslavl, Dutlov E. V. ,   SLAVNEFT-YANOS PJSC, Yaroslavl, Bubnov M. A. ,   SLAVNEFT-YANOS PJSC, Yaroslavl, Gudkevich R. I. ,   SLAVNEFT-YANOS PJSC, Yaroslavl, Burov E. A. ,   SLAVNEFT-YANOS PJSC, Yaroslavl, Borisanov D.V. ,   SLAVNEFT-YANOS PJSC, Yaroslavl
Published: January 2022

Purpose of this article is to compare technologies, quality parameters, determination of most rational application of diesel fuel fractions, received at stages of atmospheric (hereinafter – at), and vacuum (hereinafter – VT) oil distillation.
Repair department of the enterprise: today and tomorrow
Authors:   SLAVNEFT-YANOS PJSC, Yaroslavl, Kuchin D. P. , Lypko L.V. ,   SLAVNEFT-YANOS PJSC, Yaroslavl
Published: January 2022

this article reviews the development of the repair and mechanical department of SLAVNEFT-YANOS PJSC since the foundation of the enterprise to the present day. Thanks to its own repair production, expansion of its functionality, reliable, trouble-free and uninterrupted operation of all units of the oil refinery is ensured.
ФІНАНСОВА ГРАМОТНІСТЬ НАСЕЛЕННЯ ЯК ПРІОРИТЕТНА УМОВА УСПІШНОГО РОЗВИТКУ ДЕРЖАВИ
Authors: Повод Т.М.
Published: January 2022

У статті досліджено сутність фінансової грамотності, визначено її сучасний стан та вплив на соціально-економічні процеси в умовах сучасного розвитку, розглянуто джерела підвищення фінансової культури населення. Аналіз світового досвіду підтверджує беззаперечну необхідність фінансової освіти населення країни, що дасть змогу поліпшити не лише добробут громадян, а й сприятиме стабільності та економічному розвитку держави. Визначено роль держави і спеціальних інституцій у процесі підвищення рівня фінансової грамотності населення, а також необхідність популяризації фінансової грамотності серед молоді. Ці чинники дають змогу розглядати завдання підвищення фінансової грамотності населення як пріоритетні.
ФАКТОРИ ЗАБЕЗПЕЧЕННЯ ПРИБУТКОВОСТІ ПРИВАТНИХ ЗАКЛАДІВ ДОШКІЛЬНОЇ ОСВІТИ В КОНТЕКСТІ СОЦІАЛЬНО-ЕКОНОМІЧНОГО РОЗВИТКУ РЕГІОНУ
Authors: Карпенко Є.А.
Published: January 2022

У статті проаналізовано кількість та підпорядкованість закладів дошкільної освіти, що дало змогу підтвердити факт відсування державою на другий план приватного сектору у дошкільній освіті України протягом тривалого періоду. Обґрунтовано, що традиційна класифікація чинників розвитку дошкільної освіти не дає змогу визначити напрями збільшення прибутковості та забезпечення конкурентоспроможності приватних закладів вищої освіти. Запропоновано класифікувати фактори забезпечення прибутковості приватних закладів дошкільної освіти в контексті соціально-економічного розвитку регіону. Виділено фактори зовнішнього середовища (непрямої і прямої дії) та фактори внутрішнього середовища. Обґрунтовано, що для приватних закладів дошкільної освіти найбільш прийнятною є стратегія орієнтації на стабільний прибуток.
СТВОРЕННЯ МЕРЕЖІ БІЗНЕС-КЛУБІВ ЯК ОДИН З АЛЬТЕРНАТИВНИХ НАПРЯМІВ РОЗВИТКУ МОЛОДІЖНОГО ПІДПРИЄМНИЦТВА
Authors: Алєщенко Л.О.
Published: January 2022

Розвиток молодіжного підприємництва в країні може стати одним зі шляхів вирішення низки соціально-економічних проблем, таких як створення робочих місць, скорочення рівня безробіття, підготовка кваліфікаційних кадрів. Водночас цей вид бізнесу є досить непопулярним. Основними причинами цього є не лише недостатня підтримка як на регіональному, так і на державному рівні, а й відсутність у більшості регіонів країни платформ для молодих людей, за допомогою яких вони могли б отримувати актуальні знання й навички, обмінюватися інформацією, розробляти власні ідеї, отримувати консультації експертів. Одним з альтернативних напрямів популяризації ведення молодіжного бізнесу може стати створення всеукраїнської мережі бізнес-клубів. Його специфіка і технологія організації роботи полягатимуть у системному підході до вирішення проблеми пошуку розроблення інноваційних та бізнес-проєктів на стадіях seed та pre-seed. Молодіжні інноваційні проєкти зможуть отримувати всебічну допомогу: фінансову, консультаційну, інформаційну та організаційну. Такий комплексний підхід дасть змогу сприяти активізації залучення молоді до підприємницької діяльності. Основною метою статті є обґрунтування доцільності створення мережі бізнес-клубів як одного з альтернативних напрямів розвитку молодіжного підприємництва. Аспект наукової новизни проведених досліджень полягає в обґрунтуванні необхідності створення всеукраїнської мережі бізнес-клубів, метою роботи якої має стати об’єднання молодих енергійних людей, які б володіли актуальними знаннями та прогресивним мисленням для започаткування успішного бізнесу. У дослідженні розроблено основні концептуальні положення створення цієї мережі, структуру й механізми її формування, сформульовано основні результати.
ІНСТРУМЕНТИ КОНТРОЛІНГУ В СИСТЕМІ ЕКОНОМІЧНОЇ БЕЗПЕКИ ПІДПРИЄМСТВА
Authors: Бойко В.В. , Вінник В.О.
Published: January 2022

У статті визначено стратегічну важливість контролінгу в процесах мінімізації ризиків невизначеності прийняття управлінських рішень на підприємстві. Ідентифіковано передумови обґрунтування інструментів контролінгу в системі економічної безпеки підприємства. Проведено SWOT-аналіз стану використання контролінгу вітчизняними підприємствами в системі їх економічної безпеки. Розроблено матрицю узгодження завдань і пріоритетних заходів контролінгу з базовими функціональними складовими частинами економічної безпеки підприємства (фінансовою, силовою, виробничою, ринковою, техніко-технологічною, кадровою, інформаційною та екологічною). Запропоновано реалізацію комплексу інструментів контролінгу в системі економічної безпеки, серед яких слід назвати інституційно-правові, фінансово-економічні, організаційно-управлінські, науково-методологічні та інформаційно-комунікаційні.
МЕТОДИЧНІ ПІДХОДИ ДО ОЦІНЮВАННЯ РІВНІВ РИНКОВИХ ПОЗИЦІЙ НОВОГО БРЕНДУ
Authors: Фірсова С.Г. , Деметер Д.Є.
Published: January 2022

Бренди нині є рушійною силою успішності підприємств через зростаючий рівень конкуренції та розширення асортименту на ринку пропозиції. Сильний бренд – це ключова конкурентна перевага, що стимулює споживача придбати товар. Зважаючи на важливість бренду, зауважуємо, що методики оцінювання позицій бренду на ринку нині потребують удосконалення з точки зору визначення критеріїв оцінки. Стаття містить аналіз підходів до оцінювання ринкових позицій бренду, перелік факторів, що можуть на нього впливати. Розроблено авторську модель оцінювання ринкових позицій бренду з переліком факторів впливу на бренд та їх важливості. Запропоновано графічне зображення результатів дослідження для визначення основних можливостей та позицій серед конкурентів. Стаття дає змогу практично застосовувати авторський метод для оцінювання бренду в умовах конкуренції.
Research on the Display of City Image in Macau Light and Shadow Festival
Authors: Wenying Feng , Hengtong Zhang
Published: January 2022

The lighting of the city landscape has ignited the night-time economy as a new blue ocean. Macau takes festivals as an opportunity to create a city night scene, and light and shadow festivals, as part of the popular cultural industry, are better able to expand city life, enhance the city's charm and create a city name card. This paper analyzes the main categories of the Macao Light and Shadow Festival, defines the connotation and denotative value discusses the influence of the Light and Shadow Festival on the spread and display of the city of Macao, and summarizes how the Light and Shadow Festival promotes the relationship between people and people, people and space, and people and the city. The final research findings pointed out that the future Macau Light and shadow Festival should optimize the connection between people, space and city, highlight the characteristics of the city, strengthen branding and other related recommendations.
La conciliación en conflictos con el estado como una herramienta para el desarrollo
Authors: Pérez Márquez Uriel Ángel , Reyes Ortega Luis Fernando
Published: January 2022

Este trabajo de investigación tiene como objetivo principal Analizar la función de la Conciliación como herramienta para el Desarrollo, en el marco de los conflictos con el Estado; lo anterior, partiendo de que la conciliación, tal y como ha sido concebida, busca resolver o prevenir los conflictos sin necesidad de acudir al juez. Sin embargo, esta posibilidad es compleja tratándose de conflictos con entidades públicas, entre otras cosas, porque el Estado debe garantizar y proteger el orden público y el interés general, representados en el patrimonio público. Por esa razón se exige que los acuerdos que se pretendan celebrar sean revisados por un juez especializado. Sin embargo, este proceso resta eficacia a la figura ya que desnaturaliza la esencia autocompositiva de la conciliación y además porque este juez, el de lo contencioso administrativo, tiene en su ADN la función de asesorar al ejecutivo en sus actuaciones. Es imperativo un cambio en el procedimiento que posibilite la implementación de una verdadera cultura de paz, entendida ésta en el marco de los objetivos del desarrollo sostenible.
Judicialización de la macrocriminalidad en el Marco del Derecho Penal Internacional: del análisis sociopolítico de la criminalidad a los modelos dogmático-penales aplicables a la justicia transicional
Authors: Flórez Muñoz Daniel
Published: January 2022

La justicia transicional tiene como uno de sus principales mecanismos los denominados “juicios de rendición de cuentas”, los cuales son instancias judiciales de naturaleza penal a través de las cuales se investiga, juzga y castiga los máximos responsables de crímenes graves y sistemáticos contra los derechos humanos. No obstante, los actores de dichos crímenes así como la complejidad, gravedad y sistematicidad de los mismos suponen un importante desafío dogmático para el derecho penal tradicional. Lo anterior, hace necesario que la justicia transicional se apoye en la experiencia propia del derecho penal internacional a la hora de definir modelos de judicialización colectiva que permitan la imputación individual de delitos al interior de estructuras criminales complejas. En el presente artículo se describirán algunas de las principales estrategias de judicialización colectiva utilizadas en el marco del derecho penal internacional para establecer la responsabilidad individual al interior de injustos colectivos, dichas estrategias podrían ser de enorme utilidad al interior de los procesos de judicialización de crímenes atroces en cabeza de los tribunales transicionales.
Efectividad de la consulta previa del proyecto Sociedad Portuaria Puerto Bahía, en el corregimiento de Pasacaballos de la Ciudad de Cartagena
Authors: Páez Payares Karen Margarita , Macías Seguanes Rosa Amelia , Matson Ospino William
Published: January 2022

El objetivo propuesto en esta investigación consiste, en examinar la efectividad de la consulta previa realizada en el corregimiento de pasacaballos, de la ciudad de Cartagena con motivo del proyecto Sociedad Portuaria Puerto Bahía; para ello la metodología empleada fue la de la investigación socio jurídica y aplicada para el derecho y las técnicas de recolección de la información fueron las primarias ya que se aplicaron encuestas sociales a integrantes de la base social que viven en dicha localidad, para establecer su percepción sobre el grado de cumplimiento de los compromisos adquiridos por la Sociedad Portuaria Puerto Bahía en la Consulta Previa realizada por su Consejo Comunitario, y medir estadisticamente su impacto en el desarrollo socioeconómico de dicha comunidad; además se utilizaron fuentes secundarias como la ficha bibliográfica que permitió realizar un análisis de contenido a libros, capítulos de libros y artículos científicos y elaborar así el estado de la discusión sobre la consulta previa en Colombia a nivel normativo, jurisprudencial y doctrinal. Encontramos que los resultados de las encuestas sociales aquí analizadas estadísticamente denotan según el sentir de los encuestados, el poco desarrollo social del corregimiento mencionado entre los años 2014 a 2018, aun cuando el proyecto en mención, durante el desarrollo de la consulta previa realizada por el consejo comunitario pactó unas compensaciones proporcionales al daño recibido por los afrodescendientes que allí habitan, dada la imposibilidad de gozar y usar su territorio, por poner en riesgo su vida debido a la instalaciones portuarias que tiene una terminal de líquidos al granel, que además durará instalado por tiempo indeterminado.
Harlequin Color Change: a brief literature review
Authors: Pinel Guzmán Esther , Martínez Fernández Brayan Julián , Pinel Dubón José Rafael
Published: January 2022

Introducción: en 1952, Neligan y Strange describieron por primera vez un fenómeno raro, que se produce en el periodo neonatal y se caracteriza por un cambio repentino del color de la piel, con una línea recta que divide la mitad del cuerpo como si hubiera sido "dibujada con un lápiz y una regla" que discurre por la línea media, presentando la mitad del cuerpo eritematoso y la otra pálida.
Objetivo: presentar literatura relacionada con el fenómeno del cambio de color arlequín y sus diferentes presentaciones clínicas.
Métodos: se llevó a cabo una revisión no sistemática de la literatura disponible utilizando palabras claves como “Harlequin Color Change”, “Harlequin Newborn”, “Harlequin Color Change NOT Syndrome NOT ichthyosis” además de sinónimos, que se combinaron con los conectores “AND” y “OR”, tanto en inglés como en español, en las bases de datos PubMed, ScienceDirect y Google Academics.
Resultados: el cambio de color arlequín se caracteriza por un aspecto de la piel dividida en dos zonas de color distinto. Se desconoce su etiología, pero se cree que está causado por inmadurez de la regulación hipotalámica del tono vascular periférico. Afecta aproximadamente 10% de los neonatos sanos.
Conclusiones: el cambio de color arlequín es una condición benigna, idiopática y autolimitada que no necesita tratamiento. El médico debe reconocer este fenómeno, que presenta una variedad de patrones de cambio de color. Es esencial informar a los padres de esta afección cutánea benigna y transitoria para evitar pruebas y tratamientos innecesarios. No debe confundirse con la ictiosis arlequín.
Análisis del impacto económico del Covid-19 en el comercio minorista del valle del cauca
Authors: Hernández Salazar Juliana , Palacio Mera Julián Alberto
Published: January 2022

Este artículo analiza los impactos económicos en el sector minorista generados por la COVID-19, específicamente, en algunos subsectores a analizar que corresponden al total del comercio minorista para el departamento del Valle del Cauca como consecuencia de la declaración de estado de emergencia relacionado con la propagación de la infección por el virus. Para ello, se escogieron tres subsectores que presentaron variaciones negativas en sus ventas reales en un período comprendido entre marzo de 2020 a junio del mismo año, luego, se aplicó un modelo de cambio estructural dirigido a los subsectores analizados como los Restaurantes, servicios Culturales y la línea de Vestuario. Seguidamente, los resultados obtenidos en el proceso de análisis para cada una de estas tres variables, evidencian cambios estructurales y al mismo tiempo choques estructurales ocasionados por la COVID-19 en tres periodos de tiempo, como también, la afectación en las ventas reales en los meses comprendidos de la presente investigación. Finalmente, los resultados derivados de la investigación aplicando el modelo mencionado anteriormente, permitieron entender que la pandemia deja diversos impactos negativos sobre los ingresos de los comerciantes que dependen de éstos subsectores anteriormente mencionados, ocasionando pérdidas económicas, el cierre de sus establecimientos y que tengan que buscar alternativas de ventas para seguir en funcionamiento y volver a incrementar sus ingresos.
Challenges in security and privacy in wireless communications
Authors: Romero Torres Alberto de Jesús
Published: January 2022

This Research Review Paper highlights some of the main concepts of Wireless Communication including Network Security, Privacy, and Transmission Control Protocol/Internet Protocol (TCP/IP). In equal manner, it illustrates the organizational importance to establish more effective policies to counterattack and prevent cyber-attacks and reduce cyber threats. Therefore, avoiding the financial cost occasioned by hackers and the physical harm that could be cause to an individual by the sensitive data shared via technological devices to the internet without permission.
Implementación de la metodología Sigma Seis como herramienta de gestión en el proceso de manejo de equipajes en una aerolínea en la ciudad de Cartagena
Authors: Luna Amador Jorge Armando
Published: January 2022

La presente investigación tiene como objetivo principal la implementación de la metodología Sigma Seis como herramienta de gestión en el proceso de manejo de equipajes de una aerolínea estadounidense que opera en la ciudad de Cartagena, con el fin de solventar una problemática que surgió a raíz de la insatisfacción de los clientes a causa de la mala percepción que tienen acerca del manejo de su equipaje en el vuelo de conexión que llega a Cartagena. Para el desarrollo de la metodología propuesta, se partió de una descripción detallada del proceso de gestión de equipaje, se midió el desempeñó de los subprocesos críticos dentro del mismo, luego se analizaron estos subprocesos mediante herramientas como el AMEF y Poka Yoke y, finalmente, se establecieron mecanismos de mejora y prevención de errores o fallas para incrementar la calidad en la prestación del servicio de manejo de equipajes en la aerolínea. Entre los resultados principales al aplicar la metodología, se obtuvo que el desempeño de la estación es bueno de acuerdo a las mediciones, sin embargo, al manejar un solo vuelo en conexión en Cartagena, las metas de la estación apuntan a “cero errores”, razón por la cual, se hace necesario buscar mecanismos de prevención de fallas para mejorar los indicadores de calidad del proceso de gestión de equipajes.
Desigualdad educativa en el estado de Oaxaca. Una aproximación a través del coeficiente de Gini para la educación
Authors: Favila Tello Antonio , Armas Arévalos Enrique , González Samaniego Octavio
Published: January 2022

El presente trabajo tiene por objetivo medir la desigualdad educativa en los municipios del estado de Oaxaca utilizando para ello una adaptación del coeficiente de Gini, tanto para la población en general como para la población masculina y femenina por separado, con datos del año 2015. Los resultados sugieren que las condiciones de mayor desigualdad se encontraron en los municipios de Santa María Apazco, Coicoyán de las Flores, San Miguel Santa Flor, San Martín Peras y Santa María la Asunción. Llama la atención que los centros urbanos importantes del estado no se encontraron entre los municipios más igualitarios. Los coeficientes encontrados también revelaron una mayor desigualdad educativa entre las mujeres en comparación con los hombres, en 556 de los 566 municipios estudiados.
Oportunidades de la pandemia en la educación musical universitaria: motivación para acciones académicas sustentables
Authors: Carbajal Vaca Irma Susana
Published: January 2022

Se analizaron acciones académicas realizadas en la Licenciatura en Música de la Universidad Autónoma de Aguascalientes (UAA) para dar respuesta a las demandas educativas provocadas por la situación de confinamiento iniciada en marzo de 2020. Los mecanismos motivacionales y volitivos que impulsaron las acciones fueron contrastados teóricamente e interpretados para este trabajo como oportunidades de la pandemia COVID-19, para la educación universitaria. El resultado puede considerarse un indicador hacia un cambio social que va encaminado a prácticas educativas más sostenibles.
Effectiveness of Turmeric Ethanol Extract Cream Preparation (Curcuma Longa) in Speeding up Wound Healing in Male Wistar Rats
Authors: Ling Wang , Florenly Florenly , Liena Liena , Purba Dewi Riastawaty
Published: January 2022

Injury is the loss or damage of some body tissues, due to a factor that interferes with the body's protective system. The results of several studies state turmeric rhizome extract is effective in wound healing. This study aims to find out the effect of turmeric extract (Curcuma longa) on wound healing in white rats. This type of research is experimental with the approach of Pre-test and Post-test group only control design, conducted November to December 2020. The samples used were turmeric rhizomes (Curcuma Longa) and male white rats. Determination of the size of the sample according to Federer's formula, so that the number of samples as many as 25 mice, the division of 4 treatment groups and 1 control group. The results of the study from the Anova test obtained a Sig value. Calculate 0.000 while sig value (α) is 0.05 which means sig value. Count sig < (α). This means that there is a real influence of the administration of turmeric extract (Curcuma Longa) on the healing of sores in mice. Turmeric ethanol extract (Curcuma Longa) has several bioactive compounds such as alkaloids, flavonoids, saponins, and tannins that play a role in wound healing. The optimum concentration of turmeric ethanol extract (Curcuma Longa) that can cure sores in white rats is 5%. The highest percentage of cures on k-14 days was in the positive control (Bioplacenton®) which was 95% and followed by extract 5% v/ v with a cure percentage of 90%. The creamy preparation of turmeric ethanol extract (Curcuma Longa) has an ability that is close to Bioplacenton® in healing wounds in mice.
Effectiveness of Ethanol Extract Mangosteen Peel (Garcinia Mangostana L.) in Accelerating Post-Tooth Extraction Healing in Wistar Rats
Authors: Qian Dong , Florenly Florenly , Liena Liena , Purba Dewi Riastawaty
Published: January 2022

Tooth extraction will cause a wound in the form of alveolar bone that opens in the oral cavity. Mangosteen peel has various pharmacological effects such as anti-inflammatory, antioxidant, antidiabetic, and antibacterial. The goal of this study was to find out the effectiveness of Mangosteen Peel Ethanol Extract (Garcinia mangostana L.) 45% with 90% in speeding up the healing time of post-tooth extraction wounds in Wistar rats. This type of research is an experimental laboratory with a post-test pattern only control group design. Conducted at the Laboratory of Pharmacology & Laboratory of Traditional Medicine Faculty of Pharmacy, University of North Sumatra January-March 2021. The animal is a male Wistar rat of 32 who is physically healthy. The size of the sample is determined by Federer's formula, the minimum sample size for each treatment is 16 rats. The results of the study that there is a significant relationship between the amount of fibroblast tissue per field of view in Wistar Rats after tooth extraction with the administration of mangosteen peel (Garcinia mangostana L.) with a concentration of 45% and mangosteen peel (Garcinia mangostana L.) concentration 90%, p = 0.036 (p<0.05). Mangosteen skin extract (Garcinia mangostana L.) is 45% and 90% effective in speeding up wound healing time after extraction of rat teeth Wistar. Mangosteen skin extract (Garcinia mangostana L.) is 90% more effective than turmeric extract (Curcuma longa) 45% in speeding up wound healing time post-extraction of rat teeth Wistar due to the flavonoid content in mangosteen skin extract (Garcinia mangostana L.) 90% which helps accelerate wound healing higher than skin extract Mangosteen (Garcinia mangostana L.) 45%.