bluuebunny/crossref_metadata_2025 huggingface dataset:
About a “Certain-uncertain” Inconsistency within the Generally Accepted Experimental Procedures of Behavioral Economics
Authors: Harin Alexander
Published: September 2024

Old problems of the mathematical description of the economic behavior of a man are briefly reviewed. They are the comparison of choices of a man between uncertain and sure games and the radically different behavior of a man in different domains. The proposed solution of the problems consists of purely mathematical methods and models. They are briefly reviewed in the Appendix. In the present article, the main attention is paid to the analysis of the experimental support of this possible solution. The generally accepted random incentive experimental procedures are discussed. A “certain-uncertain” inconsistency between the certain type of choices and the uncertain type of incentives is revealed and analyzed.
Pain Related Secondary Outcomes Associated with Cold Tonsillectomy and Role of Topical Sucralfate in Mitigating Their Severity: A Comparative Observational Study
Authors: Momand Sadaqat , Zeb Momina , Shinwari Wajih Ud Din , Ahmad Wasim
Published: September 2024

The aim of the study was to assess the pain related secondary outcomes associated with cold tonsillectomy and role of topical sucralfate to reduce their intensity. Material and Methods: This comparative observational study was conducted in the ENT department of the Pakistan Institute of Medical Sciences (P.I.M.S.), affiliated with the Shaheed Zulfiqar Ali Bhutto Medical University (SZABMU), Islamabad, spanned from December 2016 to August 2017, following institutional ethical approval. The study comprised 112 patients with recurrent tonsillitis, evenly assigned to group A (subjects) and group B (control). Tonsillectomy, employing the cold steel dissection method, was administered to all patients. Group A received 10ml of topical sucralfate every 8 hours on the zero and first postoperative days, while group B received a placebo. Comparative analysis between the groups focused on pain-related secondary outcomes, including referred otalgia and the ability to initiate a regular oral diet on the morning of the first postoperative day. SPSS version 21 facilitated data analysis, with significance set at p < 0.005. Results: In group A, the mean age was 12.14±5.17, and in group B, it was 11.53±3.95, resulting in an overall mean age of 11.83±4.59 for both groups. Among 112 patients, 55.4% (n=62) were male, and 44.6% (n=50) were female. The frequency of referred earache was significantly lower in group A (15, 26.8%) compared to group B (25, 54.6%) [n1=n2=56, p=0.049]. Intolerance to start a normal diet was significantly lower in group A (17, 30.4%) compared to group B (39, 69.6%) at the first post-op day [n1=n2=56, p=0.034].Conclusion: Utilizing topical sucralfate alongside other pain management strategies proves to be an effective approach in reducing the intensity of pain related secondary complication i.e. referred otalgia and intolerance to oral intake among patients undergoing tonsillectomy using the cold steel dissection technique.
Revolutionizing Periodontics: The Impact of Digitalization on Diagnosis and Treatment
Authors: Chandrasekar Devadharshini , Kumari Dr. Burnice Nalina , Ravi et. al. Nikita
Published: September 2024

The objective of this review is to explore the impact of digitalization on periodontics, with a particular focus on its role in enhancing both diagnosis and treatment. Drawing from a range of recent technological advancements, the study reviews the implementation of advanced imaging techniques and artificial intelligence (AI) in clinical practice. Key digital tools such as cone-beam computed tomography (CBCT), digital intraoral scanners, computer-aided design and manufacturing (CAD/CAM), and 3D printing are examined for their contributions to the field. The results indicate that the integration of CBCT and digital intraoral scanners enables precise early detection of periodontal diseases, while AI refines diagnostics through predictive analytics and facilitates personalized treatment plans. Additionally, CAD/CAM and 3D printing technologies support minimally invasive procedures and the creation of custom dental prosthetics, leading to improved patient outcomes. Overall, the review highlights the significant potential of digital tools to optimize clinical workflows and elevate patient care standards, in alignment with contemporary policies aimed at advancing healthcare through technology.
When Diapers are Erotic: Investigation of 197 People with Adult-Baby-Syndrome (Autonepophilia)
Authors: Kasten Erich
Published: September 2024

Goal: Autonepophilia is a behaviour of adults in which people behave like toddlers. They wear diapers, suck on pacifiers and love it to be cared for from other people. Often an erotic component is involved and urinating into the diaper is connected with sexual arousal. Currently only a small number of studies exist about the AB/DL-syndrome (adult baby / diaper lovers). This study aimed to characterize causes in the development and typical behaviours of affected persons. Method: Data were collected in social networks and online communities for adult baby / diaper lovers. A sample of 184 male and 13 female participants with AB/DL behaviour was recruited and compared with a not-affected control group (158 male and 13 female). Primarily a questionnaire was used, which was developed to collect data about this syndrome by the authors. In addition the elements of the „Giessen-Test-II“ (GT-II, Beckmann et al.) and the „Need Inventory of Sensation Seeking“ (NISS, Hamelstein et al.) were used. Results: Data support a psychodynamic, behavioural and biopsychological explanation for AB/DL behaviour. Predisposing factors were the absence of a secure attachment object, lower stimulation in the anal stage, associations between infant care and first sexual arousal, enuresis and testosterone deficiency. The main motive was the reduction of stress and tensions. In contrast to the short excitement, in a long term practicing of AB/DL led to strong feelings of humiliation and shame. Moreover, AB/DL affected individuals had fewer, shorter and poorer-qualities of partnerships compared to the control group. No significant differences were found with respect to the expression of docility or sensation seeking. Conclusion: The study shows evidence of a psychodynamic explanation for the Adult Baby Syndrome. The absence of a safe attachment object and understimulation in the anal phase of development were identified as possible predisposing factors. In combination with the fact, that AB/DL sufferers more often come from divorced and adoptive families, it can be assumed that the origin of this behaviour is in the external circumstances of childhood and youth.
Bioinoculation Strategies for Enhanced Growth and Development of Economically Important Dalbergia latifolia Roxb
Authors: Mishra Atmaja Elina , Bhuyan Biswasana , Gupta Nibha
Published: September 2024

The present experiment was conducted to evaluate the plant growth properties of the native rhizospheric microflora of Dalbergia latifolia, an important medicinal, timber and biofuel plant. A systemic isolation, characterization and identification of rhizospheric soil, collected indigenously, initially produced 45 numbers of fungi and 3 numbers of bacteria. Both groups of organisms were characterized for their extracellular useful activity, especially phosphate solubilisation potential, and presented in terms of solubilisation index and solubilisation efficiency. Two fungi and two bacteria with good phosphate solubilization activity, along with NPK and organic manure, were selected and used in a pot culture experiment to promote the growth and development of Dalbergia latifolia under nursery conditions. Data recorded on 90 Days of plant growth exhibited the growth promotion of inoculated plants over control uninoculated experimental set. Results obtained on morphological and physiological growth parameters exhibited that the application of Aspergillus flavus followed by Burkholderia territorii + org. manure showed maximum shoot height and inoculation of Burkholderia anthina + Aspergillus sp. + NPK was significantly higher leaf area. Significantly longer root has been observed in Burkholderia territorii. However, a difference was observed in the number of leaves in Aspergillus flavus. + Org. manure and higher numbers of branches were observed in Aspergillus flavus only as compared to uninoculated control. Coinoculation of Aspergillus flavus + Penicillium simplicissimum showed better performance in fresh and dry shoot biomass as compared to other treatments. Burkholderia territorii + Org.manure produced higher fresh biomass of roots and coinoculation of bacteria Burkholderia territorii + Burkholderia anthina helped in enhancing root dry biomass. Dual inoculation of Aspergillus flavus + Penicillium simplicissimum gives better result in both fresh biomass of leaves and dry biomass of leaves. Application of Aspergillus flavus + Penicillium simplicissimum enhanced the total fresh biomass of the seedlings whereas supplementation of Burkholderia anthina + Penicillium simplicissimum enhanced the total dry biomass. Coinoculation of Aspergillus flavus + Penicillium simplicissimum showed higher RGR and coinoculation of Burkholderia anthina + Aspergillus flavus + NPK showed quite higher Leaf area ratio (LAR cm2gm-1). Co inoculation of Burkholderia territorii + Burkholderia anthina + Organic Manure showed highest root-shoot ratio and Coinoculation of Penicillium simplicissimum + Org. manure showed higher Net assimilation rate (NAR). However, Bacterial and fungal inoculants were also used as potent bioinoculants for the growth and establishment of crops of forest tree species.
Early Childhood Education Teachers’ Use of Teaching Learning Resources in the Implementation of Play-Based Activities within the Hemang Lower Denkyira District of Ghana
Authors: Adu Justina , Awortwe Isaac , Owusu Esther
Published: September 2024

The main purpose of this study was to assess ECE Teachers’ use of teaching learning resources in the implementation of play-based activities within the Hemang Lower Denkyira District. The study adopted the qualitative research approach. The case study design was adopted for this study. Semi-structured interview guide and observation checklist were the instruments utilized to collect data from ten (10) participants, nine (9) professional Early Childhood Education Teachers and one (1) District Early Childhood Coordinator for this study. The purposive sampling was used in selecting the participants for the study. The data were analyzed thematically with the help of Taguette, an online qualitative analysis software. The findings of the study revealed that, Early Childhood Centres do not have audio materials like Bluetooth speakers for oral and listening activities. The study also found that, most schools have no access to electricity and so lack television set and computers to aid in audio-visual lessons. Lastly, it was revealed from the study that, most Early childhood teachers used improvised materials instead of realia to enhance first hand experiences of learners. The study hence recommends that; The Stakeholders of education such as; Parent Association (PA), School Management Council (SMC), Headteachers, Teachers and the Mission units should resource Early Childhood Centres with enough, varieties, and developmentally appropriate play resources/materials and equipment to facilitate play-based pedagogies at the early childhood centres. It could be concluded from the study that; teachers’ ability to meaningfully use TLRs in their lessons and to create the necessary environment and opportunities for their children to have access to the TLRs and to manipulate them is central to the successful implementation of play-based pedagogy. Therefore, relevant resources/materials such as Audio, audio-visual and concrete materials are to be provided to promote play-based pedagogies at the early childhood centres.
“You don’t have to say much; paint it then!”: A Thematic Analysis of Mural Arts in Iraq (Mosul and Erbil as a Case)
Authors: Taher Shamal , Halawachy Huda
Published: September 2024

People find themselves in need of adding some inspiration indoors; interior designers likely let their customers immerse in the charm of some wall art decor with sweet family room wall quotes like “Love begins at home”. The art of filling walls exceeds the interior spaces for decoration, including outdoor spaces where different forms of artistic expression are used. This wall art matters among populations globally as it conveys different messages to the public and the decision-makers as well. The current article investigates Mural Arts (MAs) in Mosul and Erbil, Iraq. The researchers aim to (1) interpret the variety of themes that Mosuli Artists (MoAs) and Erbili Artists (ErAs) communicate via painting and (2) figure out the shared and distinctive theme in MoAs and ErAs’ artwork. This study employed a qualitative approach to grasp the themes of MAs in both Mosul and Erbil. The researchers gathered 60 Mixed Mural Arts MMA samples (verbal and visual); 38 in Mosul and 22 in Erbil in four months (from 8 August to 20 November 2023). They purposefully covered a broad range of sites including street walls, building facades, government institution walls, school walls, and bridge side walls in both cities. The researchers employed the Thematic Analysis Approach (TAA)by Braun and Clarke (2006) benefiting from NVivo 11(1999-2017) software to induce themes in Mosul and Erbil. This study revealed a total of 13 themes in both Mosul and Erbil in Mosul and 5 in Erbil. 2 themes, viz. ‘Environmental Sustainability’ and ‘Patriotism’ were shared. Other 6 themes viz, ‘The Transformative Power of Knowledge’, ‘The Horse as a Symbol of Nobility’, ‘Reviving the City of Mosul’, ‘Women Abuse’, ‘Unity for Iraq’, and ‘Martyrdom’ were said to be distinctive in Mosul whereas 3 other themes, viz. ‘The Role of Women in Society’, ‘Music Therapy’, and ‘Motivation in Learning’ were interpreted in Erbil.
Reading Nick Joaquin: Magic Realism and Filipino Psyche
Authors: Cañete April Rose U. , Sumicad Rulthan , Cuevas Gloria Con-ui
Published: September 2024

The term ‘magic realism’ extensively refers to the style of writing or technique that includes magical and supernatural events narrated realistically. This research investigates the elements of magic realism in Nick Joaquin’s select short stories, The Mass of St. Sylvestre, Dona Jeronima, and May Day Eve, as juxtaposed with reality, specifically on the magic realism and realities, cultural milieu, and Filipino psyche. The assumption is supported by the literary theories of Mary Ann Cain’s Formalism Theory, Homi K. Bhaba’s Postcolonialism Theory, and Aristotle’s Mimetic Theory. This research uses qualitative methods and discourse analysis. The findings of this study demonstrate that the existence of magic realism juxtaposes with the realities, the cultural milieu displays the different Filipino culture and identity, and the Filipino psyche is depicted in the other short stories. Based on the findings of this research, it has been found that the elements of magic realism and realities are revealed in Nick Joaquin’s selected Philippine short fiction, namely, The Mass of St. Sylvestre, Dona Jeronima, and May Day Eve. In the future, a more in-depth and advanced study focusing on a unified theme of the plot, characterization, and setting could be done to reveal the prevalence of magic realism as juxtaposed with reality. Specific conflicts could be studied for a deeper understanding of the cultural milieu, and more stories could be used to reveal the Filipino psyche of ordinary Filipinos.
Unveiling the Apathy: Understanding the Causes of Student Disengagement in Student Governance
Authors: Tiongzon Joshua Mata , Sumicad Rulthan , Adolfo Ana Luna L. , Margallo Danilo , Jumao-as Jhay Myka
Published: September 2024

This study delved into the causes of student disengagement in any form of student-based governance of the University of Cebu College of Arts and Sciences Department's Student Body Organization (CAS-SBO) during the academic year 2023-2024. A descriptive phenomenological research design was employed, exploring participants' experiences in student governance, how these experiences influence their lack of total disengagement and the strategies that could revitalize their engagement and active participation in the said area. Data were gathered through in-depth interviews with twelve students selected via linear snowball sampling, focusing on those with prior governance experience who did not participate in recent CAS-SBO activities. Thematic content analysis revealed nine emergent themes: (1) Lack of Connection, Inequality in Representation, and Faculty Intervention as essential experiences in student governance; (2) Student Unfamiliarity, Feeling Unrepresented, and Unmet Expectations as reasons for disengagement; and (3) Inclusive Activities, Addressing Electoral Disparity, and Empowered Leadership as potential strategies to increase engagement. Based on these findings, the study recommends regular CAS-SBO general assemblies, teambuilding exercises, leadership seminars, and the election of representatives for each degree program to foster more vital student involvement and improve representation. The study also suggests future research topics, including electoral system reforms and former CAS-SBO presidents' experiences.
Tracer Study of the Bachelor of Arts Graduates of the University of Cebu-Main Campus from 2019-2024
Authors: Sumicad Rulthan , Cuevas Gloria Con-ui , Gimarangan Rommel T. , Pacaldo Joavanni M. , Geraldizo-Pabriga Maria Gemma
Published: September 2024

This study determined the factors influencing job placement among graduates of the College of Arts and Sciences at the University of Cebu-Main Campus between 2019 and 2024, serving as a basis for proposed curriculum enhancements. The study used descriptive research design methods with the adopted-modified questionnaire, with frequency counts and percentages applied to analyze the results. Findings reveal that graduates, particularly those from the Psychology, Political Science, and English programs, are highly employable, whether through direct applications or referrals. Key factors influencing job choices include career challenges, salary, and benefits. The study also highlights a notable gender disparity, with most female graduates and a steady increase in graduates during the study period, peaking in 2024. Although the employment rate is high, most graduates occupy rank-and-file positions, with fewer advancing to managerial roles. Also, many graduates eventually shift to fields unrelated to their studies, indicating a potential mismatch between education and career progression. Graduates identify communication, human relations, problem-solving, and critical thinking as essential skills in their professional roles. These insights suggest the need for curriculum adjustments to align education with long-term career success better.
Student Commuters’ Perceived Level of Stress
Authors: Sumicad Rulthan , Palanas Karyl Vivien G. , Ebesa Adrian B. , Sesante Maribel A. , Nuñez Kate Antonette , Pacaide Angelo , Navarro Hanne Lore D.
Published: September 2024

This study, conducted during the academic year 2023-2024 at the University of Cebu Main Campus, aimed to establish the student commuters’ perceived level of stress among the currently enrolled students in the institution. Using a sample size application generator ,150 students were carefully selected from the population. The Descriptive Correlational Method was employed to seek the connection between the perceived level of stress and different variables, with a focus on these students who might be susceptible to commuting related stress. The study employed a researcher-made survey questionnaire consisting of forty (40) items on a four-point Likert scale (from Not Stressful at all to Very Stressful) and conducted a pilot test to ensure questionnaire’s internal consistency and reliability. Data were collected via face-to-face interaction, and chi-square test was utilized to know if significant relationship was established between the profile of the respondents and their perceived level of stress. Also, Kruskal-Wallis test was used to determine whether there is a significant difference in the respondents' reported stress level when grouped by profile. The results revealed that students' perceived level of stress was so high (very stressful), with no significant relationships between the perceived level of stress and the profile such as sex, age, department. However, a significant difference was found between respondents' perceived level of stress among different year levels. This study highlights the need for supportive measures to enhance the respondent’s well-being and mitigate the perceived level of stress they have experienced.
Analisis Displacemet Connecting Rod Menggunakan Metode Elemen Hingga Dengan Material Titanium Alloy
Authors: Erdyno Nafi’ , Tjiptady Bella Cornelia , Rohman Mojibur
Published: September 2024

Connecting rod merupakan komponen berupa batang penghubung antara piston dan crankshaft. Connecting rod memiliki fungsi untuk meneruskan daya dari piston ke crankshaft dengan mengubah gerak naik turun (translasi) pada piston menjadi gerak rotasi pada crankshaft. Connecting  rod mendorong piston pada sistem pembakaran  yang terdapat di ruang silinder karena terkompresinya bahan bakar dan udara. Permasalahan yang ada yaitu connecting rod harus mampu menahan beban tekan, tarik dan tegangan lentur yang diakibat oleh gaya dorong maksimum pada piston. Sehingga perlu adanya perancangan desain connecting rod menekankan pada hasil pengujian dengan tekanan yang telah di tentukan mulai dari tekanan 300 N, 500 N dan 1000 N. Subjek yang di analisis hasil pengujian yaitu displacement,stress,dan strain. Bahan material yang digunakan titanium alloy karena material ini memiliki kekuatan yang baik, dan memiliki ketahanan korosi yang bagus. Dengan kata lain dasain connecting rod motor yang baik, harus memiliki kekuatan yang baik, aman dan sesuai dengan kebutuhan maka pemilihan material sangatlah berpengaruh pada kinerja connecting rod ini. Metode yang digunakan adalah Metode Elemen Hingga (MEH) dengan software solidworks 2014. Analisis dilakukan pada desain connecting rod motor dengan berdasarkan hasil analisis dengan MEH, dinyatakan bahwa connecting rod dengan bahan material titanium alloy dengan working pressure maksimal 1000 N, kuat dan aman untuk digunakan.
Implementasi Sensor PH Untuk Budidaya Hidroganik pada UMKM Bengkel Mimpi Berbasis IoT
Authors: Ma'rifatillah Aulia Faridatu , Al Azhar Gillang , Saukani Imam
Published: September 2024

Budidaya sistem hidroganik merupakan bentuk inovasi yang ditemukan oleh UMKM Bengkel Mimpi dalam mengatasi permasalahan berkurangnya lahan di Inondesia. Dalam sistem hidroganik terdapat pemanfaatan kolam ikan lele yang mana dalam pengecekan kondisi airnya masih menggunakan cara konvensional yang masih kurang efektif. Ikan lele dapat bertahan hidup dalam kadar pH antara 6.5-7.5 agar tidak mudah terserang penyakit hingga kematian massal. Terdapat penggunaan larutan garam dan larutan pH down yang bertujuan menetralkan kadar air apabila terdeteksi pH tidak dalam rentang yang dibutuhkan. Sehingga dibuatnya penelitian ini untuk mengatasi masalah tersebut dengan mengintegrasikan dalam sistem kontrol dan monitoring berbasis Internet of Things (IoT) melalui Blynk. Sistem ini menggunakan ESP32 untuk mengelola data hingga mengontrol gerak pompa mist sprayer dan sensor PH E201-C sebagai feedback dari kontrol PID. Dengan menggunakan metode kontrol PID pada sistem ini daidapatkan parameter kontrol dengan nilai Kp = 3.9, Ki = 0.01, Kd = 0.042 dengan menghasilkan kurva respon sistem Rise Time = 63s, Delay Time = 38s, Peak Time = 70s, dan Settling Time = 82s yang menghasilkan pompa mist sprayer dapat bekerja stabil dalam mengeluarkan larutan untuk menetralkan kadar pH dan mempertahankan setpoint yang telah ditentukan.
The Influence of a Mother Tongue on English Pronunciation While Acquiring English as a Second Language
Authors: Taefi Mawaddah Mohammed
Published: September 2024

This study aims to investigate the role of the mother tongue on English pronunciation in the acquisition of a second language. Many people face issues while acquiring English as a second language. These issues can be divided into two main categories: the impact of a mother tongue on second language and ineffective teaching approaches. This study focuses on the first category which means the influence of the native language of the learner on their acquisition of the target language. The researcher used a mixed method in the present study and asked the participants to record their voices while pronouncing certain vowels and consonants. After that, the data were collected and analyzed from audio recordings based on the International Phonetic Alphabet system. There are 40 participants including 20 females and 20 males from four nationalities: Saudi, Mexican, Turkish, Filipino. The results showed that the findings of the study answered the research questions about the influence of the mother tongue on learners’ pronunciation while acquiring English as a second language. It showed that participants faced problems because of the influence of their mother tongue. It also answered the second research question about the difference between L2 learners’ pronunciation based on their gender. In general, there was a difference between genders when pronouncing English by learners from different countries, where male participants had higher numbers of mispronunciations than female participants.
Implementation of The Kampus Mengajar Policy Program in Enhancing Literacy, Numeracy, and Technology Adaptation
Authors: Subagdja R Oetje , Qotrunada Rasya , Pratidina Ginung
Published: September 2024

The aim of this research is to understand how the Kampus Mengajar program enhances literacy, numeracy, and technology adaptation in Ciderum Village, Caringin District. The policy implementation theory used in this research is the Implementation Policy theory by George Edward III, which includes four dimensions: Communication, Resources, Disposition, and Bureaucratic Structure. The research applies a qualitative descriptive research method, relying on information gathered through observation, interviews, and documentation. The analysis techniques include data summarization, presentation, and drawing conclusions. The results indicate that the implementation of the Kampus Mengajar program in literacy, numeracy, and technology adaptation learning can be considered good. The school has implemented literacy, numeracy, and technology adaptation learning and collaborated with teachers and parents in the learning process for each student. Although the implementation at SDN Cikereteg 03 is not yet optimal and maximal, the school continuously strives to ensure that it can be implemented optimally and maximally for all students.
Analysis of Erythrocyte Parameters in Multiple and Long-Term Blood Donors from Northern Pomerania (Poland)
Authors: Kurhaluk Natalia
Published: September 2024

Background/Aims: Assessment of the levels of vital blood parameters in donors is essential to evaluate their health status, ensure their suitability for donation, preserve the integrity of the circulatory system, and facilitate comprehensive health monitoring. The aim of our study was to analyse the levels of haemoglobin, haematocrit, erythrocyte count, MCV, MCH, and MCHC in 12 groups of first-time donors and experienced donors of both sexes at the John Paul II Regional Blood Donation and Treatment Centre in Słupsk, northern Poland. The donors were divided into three age groups (18-30 years, 31-45 years, and 46-65 years). Methods: Using MANOVA multivariate significance tests, we examined the main effects of donor-related factors (age, sex, donor stage) on morphological blood parameters to evaluate different haematological parameters, such as Hb, Ht, RBC, MCV, MCH, and MCHC, and identified statistically significant relationships between all variables. Results: The multivariate analysis of these three main factors showed that the variation in haemoglobin (Hb) levels accounted for 46% of the explained dependence in this statistical model. In particular, approximately half of the variability in the multivariate statistical analysis was attributed to the role of Hb and haematocrit (Ht). In addition, the β-coefficient values for Hb and Ht were statistically higher in relation to donor sex and donor type (single versus repeat). These β-coefficient values from our data represent the strength and direction of the relationship between the haematological parameters (Hb and Ht) and the specific donor characteristics. A higher β-coefficient indicates a stronger influence of donor sex and donor type on these parameters, suggesting that these factors contribute significantly to the variation in the Hb and Ht levels. Based on our results, the comprehensive analysis of the entire statistical model of metabolic biomarkers revealed the following hierarchy: Hb > Ht > MCHC > MCV > RBC > MCH. The results obtained showed strong statistical relationships, as indicated by the high values of the key statistical indicators in our analysis. The coefficient of determination (R²) showed that the model explained a significant proportion of the variance in the data, while the F-test statistic confirmed the significance of the predictors. Conclusion: These strong statistical dependencies provided a clear justification for selecting this model over others, as it effectively represented the underlying relationships within the data. These statistics help to assess how well the model matches the actual data, thereby helping to reduce the risks associated with blood donation, optimise donor safety, and maintain the quality and efficiency of blood transfusion services.
GNAS, not a Highly Mutated Gene, Has Prognostic Significance and Carcinogenic Effects in Osteosarcoma
Authors: Qi Jin , Huang Yanjiao , Bian Yaogang
Published: September 2024

Background/Aims: Osteosarcoma is a prevalent and aggressive primary malignant bone tumor affecting children and adolescents. Despite advancements in sequencing technologies, there remains a lack of reliable prognostic biomarkers and effective targeted therapies for osteosarcoma. This study focuses on identifying key prognostic genes, particularly the role of GNAS, in osteosarcoma progression. Methods: Bioinformatics analyses were performed on osteosarcoma datasets from the Gene Expression Omnibus (GEO). Differential gene expression analysis, weighted correlation network analysis (WGCNA), and survival analysis identified potential prognostic hub genes. The expression and function of these genes were validated through immunohistochemistry and animal experiments. Specifically, the role of GNAS was investigated through siRNA-mediated knockdown in osteosarcoma cell lines and nude mice models. Results: Five hub genes (PROP1, GNAS, CYP4F2, LHX3, CNGB1) were identified as significantly related to osteosarcoma prognosis. Among these, GNAS was found to be highly expressed in osteosarcoma tissues compared to normal tissues. Immunohistochemical analysis confirmed the elevated expression of GNAS in osteosarcoma samples. GNAS mutation analysis revealed a low mutation rate in osteosarcoma, suggesting its oncogenic role is independent of mutational status. Animal experiments demonstrated that knocking down GNAS significantly inhibited tumor growth and induced apoptosis in osteosarcoma cells. Conclusion: GNAS is highly expressed in osteosarcoma and associated with poor prognosis, acting as an oncogene in osteosarcoma progression. Targeting GNAS could be a potential therapeutic strategy for osteosarcoma. Further studies on GNAS-related signaling pathways may provide deeper insights into the molecular mechanisms driving osteosarcoma malignancy.
Ultrasound and Doppler Study in Assessing the Efficiency of Complex Rehabilitation in Patients with Diabetic Neuropathy
Authors: Alybaeva S. , Mambetov M. , Aimanbetova G.
Published: September 2024

The aim of the work: to evaluate the effectiveness of exercise therapy, ozone therapy, physiotherapy equipment in outpatient rehabilitation and treatment of patients with diabetic neuropathy of the lower extremities from the standpoint of the International Classification of Functioning, Disability, and Health. When evaluating the effectiveness of a monthly course of rehabilitation treatment, changes in the vessels of the lower extremities are of great importance. We were able to prove a positive change in the vessels of the lower extremities after treatment with the rehabilitation complex using ultrasound Dopplerography. In the main group, an increase in the blood flow velocity in the vessels of the lower extremities by 20.5% was noted, and in the comparison group, an increase in the blood flow velocity of the lower extremities by 12.7% was noted. The effectiveness of rehabilitation was assessed based on a comparison of the achieved rehabilitation results with the initial indicators.
Regional Anesthesia for Operations on Pathology of the Pelvic Organs
Authors: Beishenaliev A. , Atabaev T. , Abdiev A.
Published: September 2024

Article discusses regional anesthesia during operations on pathologies of the pelvic organs. Research objectives: comparative study of the epidural, spinal, intravenous and general anesthesia results during operations of pathology of the pelvic organs. Research materials and methods: literature review was carried out on the article topic for comparative results of regional anesthesia during operations of the pelvic organs. Research results: when using regional anesthesia during operations in the lower part of the abdominal cavity in the patients with pelvic pathology, a smoother course of the operation and the early postoperative period was observed comparing with general anesthesia. Conclusions: regional anesthesia for operations in the lower abdominal cavity, especially in elderly patients, is the gentlest method of anesthesia, including in the presence of concomitant diseases.
Indications for Spinal Anesthesia in Simultaneous Operations for Combined Gynecological Diseases
Authors: Beishenaliev A. , Atabaev T. , Abdiev A.
Published: September 2024

In the early postoperative period, complications usually occur in groups with a significant and high degree of surgical and anesthetic risk. For this reason, studying the indications for spinal anesthesia is relevant. To study indications for spinal anesthesia during simultaneous operations of combined gynecological diseases. The results of 123 patients’ surgical treatment with combined surgical and gynecological diseases were analyzed depending on the surgical and anesthetic risk. According to a retrospective analysis and study of prognostic indicators, postoperative complications occurred in patients with a significant and high degree of surgical and anesthetic risk. Simultaneous operations are contraindicated in cases of significant and extremely high degrees of surgical and anesthetic risk; such patients must be operated on in stages.
Clinical Acute Bulbar Syndrome in a 6-Month-Old Child with Cortical Brain Dysplasia
Authors: Zhikhareva V. , Yuldashev I. , Sulaimanov Sh.
Published: September 2024

The article presents a rare clinical case of Autoimmune brain stem encephalitis of unknown etiology in a 6-month-old girl. The manifestation of the disease began with a subacute growing bulbar syndrome, however, in the clinical picture noted hemiparesis, which was not typical for the brain stem lesions. In the series of examinations, we revealed a concomitant congenital pathology of the cerebral cortex, which was the cause of child hemiparesis. The clinical case shows the importance of differential diagnosis in limited conditions and medical alertness for the correct diagnosis and further treatment.
Medullary Nephrocalcinosis
Authors: Murkamilov I. , Aitbaev K. , Yusupov F. , Raimzhanov Z. , Yusupova Z. , Yusupova T. , Khakimov Sh. , Nurmatov Т. , Solizhonov Zh. , Abdykadyrov M.
Published: September 2024

Medullary nephrocalcinosis is a clinical variant of chronic kidney disease characterized by diffuse deposition of calcium and phosphate salts in the parenchyma, leading to inflammatory-dystrophic changes and the development of chronic renal failure. Medullary nephrocalcinosis is divided into primary (develops in previously unaltered kidneys and initially affects the proximal part of the nephron) and secondary (simultaneously affects all parts of the renal glomeruli, causing nephrosclerosis and increasing the risk of chronic kidney disease). The article describes two clinical cases of medullary nephrocalcinosis with different etiological factors. In the first case, the disease developed against the background of regular use of third-generation cephalosporins (ceftriaxone), while in the second case, it resulted from lipid and purine metabolism disorders. The genetic and etiopathogenetic aspects of medullary nephrocalcinosis are discussed. Given the importance of determining the causes and pathogenetic mechanisms of medullary nephrocalcinosis, the need for thorough diagnostics in adult patients with changes in the renal parenchyma accompanied by hyperparathyroidism, hyper- or normocalcemia, hypophosphatemia, hypomagnesemia, and hypercalciuria is emphasized. Diagnostic workup should include genetic, metabolic, and iatrogenic components of kidney damage.
Toxic and Metabolic Kidney Injury: Focus on Energy Drinks
Authors: Murkamilov I. , Sabirov I. , Yusupov F. , Raimzhanov Z. , Yusupova Z. , Yusupova T. , Khakimov Sh. , Nurmatov Т. , Solizhonov Zh. , Abdykadyrov M.
Published: September 2024

Currently, energy drinks on the market are represented by medium and highly carbonated, as well as non-alcoholic and low-alcohol products. More than 500 brands producing energy drinks are registered in the world. Long-term abuse of energy drinks can lead to serious consequences. Kidney damage caused by energy drinks is becoming an urgent medical and social problem, since with prolonged use there is dependence on them, numbness of the limbs, palpitations, headaches and dizziness, pain in the precordial region, increased blood clotting, frequent urination, irritability, depression, insomnia, increased fatigue, anxiety, fear and convulsions. Widespread and uncontrolled use of energy drinks can cause social imbalance in society, decreased mental and physical performance, especially in adolescents. The toxic properties of energy drinks are manifested depending on the volume and composition, presentation, duration of intake, as well as concomitant disease. Availability, wide popularization through advertising in the media, insufficient awareness of young people about the harmful effects of energy drinks serves as a condition for the development of damage to internal organs when consuming them. The article presents data from scientific literature on the epidemiology of risk factors for the development and progression of chronic renal failure. Negative effects on human health with long-term abuse of energy drinks are discussed. The article presents the results of clinical observation of patient N., 31 years old, who developed a neo-oliguric variant of acute kidney injury against the background of long-term use of energy drinks. Laboratory testing revealed hyperglycemia, dyslipidemia, hypercreatininemia (blood creatinine 161.0 μmol/l) and hypercytokinemia due to an increase in the serum concentration of interleukin-6. The glomerular filtration rate (GFR) was at the level of 48 ml/min. Against the background of the therapy, kidney function was restored: blood creatinine 85.9 μmol/l, GFR increased to 116 ml/min.
Cervical Spinal Stenosis - Modern Approaches to Diagnosis and Treatment
Authors: Evgrafov D. , Yarikov A. , Vishnevsky A. , Fraerman A. , Perlmutter O. , Gunkin I. , Kornakova O. , Istrelov A. , Tsybusov S. , Kotelnikov A. , Khomchenkov M. , Volkov I. , Pavlova E. , Sosnin A. , Tutkin A. , Parkaev M. , Simonov A.
Published: September 2024

The article analyzes in detail the scientific literature on the etiology, classification, diagnosis, clinical picture and treatment of spinal canal stenosis in the cervical spine. Special attention is paid to the clinical picture, diagnosis and differential diagnosis of the causes of cervical myelopathy. Further, the work presents all modern methods of treatment of cervical spinal stenosis. The researchers divided the methods into ventral and dorsal. The advantages and disadvantages of each type of operation are described. In conclusion, the authors summarized the indications and contraindications for each type of surgical aid.
Dietary Preferences and Potential Impact on Dental Hard Tissue Diseases in Schoolchildren of Osh Region, Kyrgyz Republic
Authors: Omurbekov E. , Minbaev Z. , Tynalieva R. , Abykeeva R. , Yuldashev I.
Published: September 2024

Dental caries, known as one of the civilization diseases, leads to chronic progressive destruction of teeth, impaired aesthetics, inflammatory and other complications. The conducted study of ethnic, dietary preferences and their potential influence on the prevalence and intensity of dental caries in schoolchildren of the Kyrgyzstan highland region showed a moderate degree of intensity and prevalence in the deciduous dentition (6-7 years) — 94.2%. In the permanent bite (11-12 years) — 95.5%. The average prevalence of caries of permanent teeth in schoolchildren 6-17 years old was 77.7%. Increased consumption of sugar-containing products and carbonated drinks was determined.
Hormonal Regulation of the Amount of Sugar in the Blood Converter
Authors: Seyidova L.
Published: September 2024

Although hormones differ in their place of origin, order of distribution, chemical composition and nature of action, they are united under a very important general biological pattern: they participate in metabolism, morphological differentiation of the organism, growth and development, reproduction and regulation and coordination of its basic functions. The nervous system carries out the connection and influence between different parts of the organism directly through hormones. Hormones are substances of a protein nature or steroids that act in extremely small quantities. Their effect is carried out in 2 ways: through the nervous system and directly through the blood to the organs.
State and Development Prospects of the Maternal and Childhood Care Service of the Kyrgyz Republic
Authors: Sulaimanov Sh. , Eshalieva A. , Saatova G. , Dzhetybaeva A.
Published: September 2024

The National Center for Maternity and Childhood Care (NCMCC), operating under the Ministry of Health of the Kyrgyz Republic is a premier institution dedicated to the advanced treatment, diagnostics, and overall healthcare of women and children. As a tertiary-level center, NCMCC plays a pivotal role in organizational, methodological, educational, and scientific endeavors related to maternal and child health. In alignment with its mandate, the NCMCC develops and implements comprehensive programs focusing on the prevention, early detection, and treatment of diseases. These initiatives are crucial in reducing maternal and infant mortality rates and promoting a healthy lifestyle among children and their parents. Furthermore, the center ensures the organized provision of essential medicines, specialized medical nutrition products, and other medical supplies for children.
Competency Approach in Nurse Training
Authors: Turgunalykyzy G.
Published: September 2024

In the current conditions of market relations, especially in the context of reforming the medical education system, it is necessary to change the quality of training of specialists in order to train demanded and competitive graduates of secondary vocational educational institutions using a competency approach. The competence approach contributes to the orientation of the young specialist to obtain theoretical knowledge, increasing the level of practical knowledge that a graduate of a medical college should have and his ability to master in the labor market. The opinion of medical college students about the knowledge and practical skills required by the graduate is important. To this end, a questionnaire survey of 84 medical college students was conducted. First-year students do not yet have a clear idea of ​ ​ the competence approach in the learning process and the importance of not only theoretical knowledge, but also clinical disciplines, practical communication skills. Students of the 3rd year have already formed an opinion about the importance of all subjects and motivation for future professional training. The introduction of a competency approach in the training of nurses makes it possible to conduct the educational process at a qualitative level, contributing to the training of highly qualified, competitive specialists in the medical labor market.
Sanitary and Chemical Analysis of Drinking Water and Laboratory Control of the Content of Toxic Elements of Pesticides and Mycotoxins in Food Products
Authors: Adyluulu T. , Zhunusova G.
Published: September 2024

Relevance of the study: nutrition is the most important factor in maintaining health, normal growth and development of children and adolescents, preventing a number of diseases, maintaining high performance of the adult population, maintaining active longevity. Drinking water and food are necessary for the existence of humans and all life on Earth. Issues related to increasing responsibility for the effectiveness and objectivity of quality control of drinking water and food products are relevant in guaranteeing their safety for the health of consumers. Objectives of the study: to study the quality of drinking water and the efficiency of the water supply system in Osh in the period from 2020 to 2023; analysis of compliance of drinking water quality with sanitary and chemical standards; development of recommendations for improving the quality of water and the water supply system in Osh. Determination of toxic elements, pesticides and mycotoxins in food products, determination of physicochemical indicators and toxic elements in drinking water, pesticides and mycotoxins in food products was carried out in accordance with regulatory documents of GOST and the maximum permissible concentration. The test results showed the normal and permissible levels of pH, total iron, fluorides, hardness, dry residue, ammonia, nitrates, etc. in water, and the content of aflatoxin B1, the mass concentration of cadmium and lead, hexachlorane, dichlorodiphenyltrichloroethane in food products. For a more in-depth analysis, it is recommended to use additional data on climatic conditions, geological features of the region, as well as the demographic situation in Osh.
Modeling the Optimal Distance Between Pipes in a Solar Water Heating Collector
Authors: Satybaldyev A. , Mavlyanova Zh.
Published: September 2024

This study proposes a mathematical model based on normal distribution to determine the optimal distance between pipes in a solar water heating collector. The model takes into account key system parameters such as material thermal conductivity, heat losses, and solar radiation intensity. Experimental data collected for model validation confirm its accuracy and adequacy. The main results show that the maximum efficiency (η) of the solar water heating collector is achieved at a pipe spacing of approximately 0.0469 m. The analytical method demonstrates a smooth decrease in efficiency when deviating from the optimal distance, whereas the experimental data indicate a high sensitivity of the system to changes in this parameter. Thus, the proposed model is a useful tool for designers, allowing for precise prediction of optimal system parameters and increased efficiency. Further research and experiments are planned to improve model accuracy and expand its applicability.