bluuebunny/crossref_metadata_2025 huggingface dataset:
Genus Ophioglossum L., from Western Part of India with Special Reference to Gujarat State
Authors: KACHHIYAPATEL Ronak N. , PATIL Sachin M. , PATEL Suresh K. , RAJPUT Kishore S.
Published: November 2018

The genus Ophioglossum L. is revised for the Gujarat state and there were reported eight species viz. Ophioglossum costatum R. Br., O. gramineum Willd., O. gujaratense SM Patil, RN Kachhiyapatel, R Patel and KS Rajput, O. lusitanicum L., O. reticulatum L., O. parvifolium Grev. & Hook., O. nudicaule L. f. and O. thermale Kom., from different parts of the state. Amongst these, Ophioglossum thermale Kom. and O. lusitanicum L. were collected for the first time from Jambughoda Wildlife Sanctuary and this result is documented as a new distributional record for Gujarat state.
Influence of Extraction Scheme on the Antioxidant Potential of Caralluma tuberculata
Authors: NOREEN Sobia , HUSSAIN Ishtiaq , TARIQ Muhammad Ilyas , IQBAL Shahid , BATOOL Fozia , GHUMMAN Shazia Akram , NOUREEN Shazia , KAUSAR Tusneem
Published: November 2018

Herbal industry of developing countries is facing several technical issues related to the extraction conditions in order to attain the maximum yield of a plant extract with maximum therapeutic attributes. Therefore the present study was aimed to investigate the best technique for respective herbal products. The effect of three different extraction techniques: ultrasonic assisted extraction, microwave assisted and orbital shaker assisted extraction, by using three solvents (80% methanol, ethanol, and ethyl acetate) on the antioxidant potential of Caralluma tuberculata stem (non-conventional vegetable) extracts were investigated. Folin-Ciocalteu method was applied on tested samples in order to find the concentration of total phenols. Therefore, the optimized extract of high yield and maximum total phenolic content was selected for further analysis like total flavonoid contents, FRAP, DPPH and ABTS scavenging potential. Quantification of phenolic acids in the extracts was also carried out by HPLC. Significant variation was observed in the yield of total phenols within the extracts, but better results were obtained in aqueous methanolic extract of ultrasonic assisted extraction, followed by microwave assisted and orbital shaker assisted extraction. Present findings supported the view that ultrasonic assisted extraction can be used for phytochemicals profiling, activity guided assays and the development of herbal products. Correlation coefficients of active principles indicated a significant relationship to antioxidant capacity P < 0.05.
Evaluation of Different RNA Extraction Methods from Agropatch Suppressor Assay for Small Quantities of Plant Tissue and Their Application for Analysis of Gene Expression
Authors: SHAHRIARI Amir G. , TAHMASEBI Aminallah
Published: November 2018

The agroinfiltration assay provides fast and efficient way to transiently express genes into plant cells by Agrobacterium tumefaciens. Extraction of RNA of high quality and sufficient amounts is prerequisite for gene expression studies such as quantitative Real Time PCR (q-PCR) from infiltrated areas in agropatch suppressor assay with small quantities of plant tissue. To attain prime RNA extraction from small tissues of infiltrated N. benthamiana plants with Potato virus A helper component proteinase viral suppressor protein, the efficiency of three RNA extraction methods (LiCl, TRIzol reagent and commercial kit) was evaluated. The total RNA yield with LiCl method was 2.83 and 33.2-fold greater than that of TRIzol reagent and commercial kit, respectively. Also, total RNA yield using TRIzol reagent was 11.7-fold higher than that with commercial kit. The A260/A280 ratio mean for TRI reagent (1.95) and kit (1.9) extractions were within the optimum range.q-PCR revealed that the cycle threshold values of housekeeping gene, EIF-1α and target genes AGO1 and ATG6 for RNA extracted using LiCl and kit were 1.07 to 1.3 and 1.02 to 1.12 times higher than those evaluated with the TRIzol method. Overall, TRIzol method showed the most effective approach for obtaining RNA from N. benthamiana patches in gene expression studies.
Testing The Biodegradability of Priority And Emerging Contaminants As A Mixture
Authors: TEZEL Ulas , ŞEPİTCİ Begüm
Published: November 2018

Currently about 110,000 chemical substances are present in the European market. The fate of most of those chemicals in the environment is not known. However, biodegradability of those chemicals should be tested before they are registered to the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) System. Current protocols offered by The Organisation for Economic Co-operation and Development (OECD) for testing the biodegradability of the chemicals are limited mainly due to they are low throughput and do not reflect real-world conditions. In OECD protocols, the biodegradability of a single chemical is tested. However, many chemicals coexist in the environment. In addition, experiments are set at a very high initial chemical concentration that is not expected in the environment. Both limitations are due to the lack of an analytical method which can measure multiple compounds simultaneously at very low concentrations. In this study, we coupled OECD 314 Simulation Tests to Assess the Biodegradability of Chemicals Discharged in Wastewater protocol with a powerful liquid chromatography mass spectrometry with scheduled multiple reaction monitoring and tested the biodegradability of 32 priority substances and chemicals with emerging concern. Only seven chemicals were degraded in the test within 28 days. The biodegradation half-lives of those degradable chemicals ranged between 0.6 to 18 days. Acetaminophen was degraded the fastest whereas biodegradation of sulfamethoxazole took longer than the rest of the biodegradable chemicals tested. The novel methodology described here can be applied to test biodegradability of different chemicals as a mixture and adopted as a standard protocol.
Selective protection and labelling of arginine/lysine side chains in HBSs of proteins v1
Authors: Thao Bui Phuong
Published: November 2018

Interactions between heparan sulfate proteoglycans and the partner proteins regulate many aspects of cell functions, however, their binding properties are still equivocal. Developed eight years ago was a method for selective labelling of lysine residues in the heparin binding sites of Fibroblast Growth Factors (FGFs). The labelling of arginine residues is far more challenging, due to the multiple reaction products between a dicarbonyl and a guanidino group.
Protocols from: Invasion genetics of the silver carp (Hypophthalmichthys molitrix) across North America: Differentiation of fronts, introgression, and eDNA detection v1
Authors: Stepien Carol , Elz Anna , Snyder Matthew
Published: November 2018

This protocol describes the data collection and analysis performed in "Invasion genetics of the silver carp (Hypophthalmichthys molitrix) across North America: Differentiation of fronts, introgression, and eDNA detection". Published in PLOS One, 2018. The invasive silver carp Hypophthalmichthys molitrix escaped from southern U.S. aquaculture during the 1970s to spread throughout the Mississippi River basin and steadily moved northward, now reaching the threshold of the Laurentian Great Lakes. The silver carp is native to eastern Asia and is a large, prolific filter-feeder that decreases food availability for fisheries. The present study evaluates its population genetic variability and differentiation across the introduced range using 10 nuclear DNA microsatellite loci, sequences of two mitochondrial genes (cytochrome b and cytochrome c oxidase subunit 1), and a nuclear gene (ribosomal protein S7 gene intron 1). Populations are analyzed from two invasion fronts threatening the Great Lakes (the Illinois River outside Lake Michigan and the Wabash River, leading into the Maumee River and western Lake Erie), established areas in the southern and central Mississippi River, and a later Missouri River colonization. Results discern considerable genetic diversity and some significant population differentiation, with greater mtDNA haplotype diversity and unique microsatellite alleles characterizing the southern populations. Invasion fronts significantly differ, diverging from the southern Mississippi River population. About 3% of individuals contain a unique and very divergent mtDNA haplotype (primarily the southerly populations and the Wabash River), which may stem from historic introgression in Asia with female largescale silver carp H. harmandi. Nuclear microsatellites and S7 sequences of the introgressed individuals do not significantly differ from silver carp. MtDNA variation is used in a high-throughput sequence assay that identifies and distinguishes invasive carp species and their population haplotypes (including H. molitrix and H. harmandi) at all life stages, in application to environmental (e)DNA water and plankton samples. We discerned silver and bighead carp eDNA from 10 bait shops in the Great Lakes watershed, indicating that release from retailers comprises another likely vector. Our findings provide key baseline population genetic data for understanding and tracing the invasion’s progression, facilitating detection, and evaluating future trajectory and adaptive success.
Use of various strategies of mixed methods research in organizational culture diagnosis
Authors: Lipatov S.A.
Published: November 2018

Differences between quantitative and qualitative methods at various levels are described. The advantages and disadvantages of these groups of methods are analyzed in relation to the process of studying the culture of the organization, it is concluded that the separate use of only one class of methods in the diagnosis of organizational culture can lead to the construction of an inadequate picture. The emergence of a strategy of “mixed methods” is quite natural phenomenon. However, the joint use of different methods in one study involves solving a number of methodological problems of their interrelation. We consider a variant of the theoretical justification that guides such studies, proposed by J. Green and her colleagues, based on which three strategies for mixing quantitative and qualitative methods in diagnosing the culture of an organization are described: triangulation, addition, and development. It is supposed that these strategies can be combined in the process of an organizational culture diagnosis in order to obtain a more complete, reliable and most relevant result.
Adaptation of «Proactive coping inventory» Adaptation of «Proactive coping inventory»
Authors: Belinskaya E.P. , Veсherin A.V.
Published: November 2018

The article presents the results of adaptation and correction of the Russian-language version of the questionnaire “proactive copying inventory”. This questionnaire was translated into Russian by E.S. Starchenkova, but the results of its psychometric verification are not available in publications. The original Russian version of the questionnaire showed good consistency of scales (Cronbach’s alpha was greater than 0.77), but unsatisfactory compliance with empirical data by the results of confirmatory factor analysis (χ²(df) 3025.73 (1259); p <0.01; CFI 0.76; TLI 0 , 75, RMSEA 0.056). Based on the analysis of the theoretical model of the classification of coping behavior using the Confirmatory Factor Analysis, a shortened version of the questionnaire was proposed which has good indicators of compliance with the original data (χ²(df) 509,05 (307); CFI 0.95; TLI 0.94; RMSEA 0.04). The abbreviated version showed good indices of internal discriminant validity, and significant correlations were also obtained with the scales of the COPE questionnaire that were close in content.
Graphene Katkılı Sıvılaştırılmış Fındık Kabuğu Polyvinyl pyrrolidone (PVP) Nanoyüzeylerin Elektrospinning Tekniği İle Elde Edilmesi Ve Karakterizasyonu
Authors: YAZICI Mustafa , ÖNAL Ömer , KONUŞ Oğuzhan
Published: November 2018

Bu
çalışmada, yüksek iletkenlik özelliğine sahip çok hafif ve çok mukavemetli bir
madde olan grafen, sıvılaştırılmış Fındık Kabuğu / Polyvinyl pyrrolidone
(PVP)  karışımına katılarak
Elektrospinning tekniği ile nano yüzeyler elde edilmiştir. Önce fındık kabuğu,
fenol (phenol) ve diğer kimyasallarla muamele edilerek sıvılaştırılmış
(Liquefied hazelnut shell, LHS), daha sonra etanol ile çözelti haline getirilen
PVP ile sıvılaştırılmış fındık kabuğu çözeltisi belli oranlarda grafen ile
katkılandırılarak  homojen karışım elde
edilmiştir. Elde edilen homojen karışımdan yarı endüstriyel elektrospinning
cihazında nanolifli yüzeyler (nano malzemeler) üretilmiştir. Üretilen nano
yüzeylerin yapısal, morfolojik, termal ve elektriksel özellikleri
incelenmiştir. Grafen oksit, grafen, grafen/fındık kabuğu, grafen pvp,
grafen/fındık kabuğu/PVP örnekleri SEM, EDX, FTIR, Zeta Potansiyeli ve Raman
analizleri ile karakterize edilmiştir.
Göknar (Abies bornmülleriana Mattf.) Ahşabının Yüzey Pürüzlülüğü Üzerine Zımparalama ve Kesiş Yönünün Etkisi
Authors: ÖZDEMİR FERHAT , DALGIÇ Eda , ÖZYURT Hamit , RAMAZANOĞLU Doğu , TUTUŞ Ahmet
Published: November 2018

Bu çalışmada Göknar (Abies
bornmülleriana Mattf) ahşabının yüzey pürüzlülüğü üzerine zımparalama ve kesiş yönünün
etkisi araştırılmıştır. Daire testere ile radyal ve teğet yönde kesilen göknar ahşap
numuneleri sırasıyla 60, 80, 100 ve 150 numaralı zımpara ile zımparalama işlemi
uygulanmıştır. Zımparalama işlemi yapılan numunelerin yüzey pürüzlülük
parametre değerleri ISO 4287 standardına göre ölçülmüştür. Elde edilen verilere
göre yüzey pürüzlülük değeri hem radyal hem de teğet yönde zımpara numarasının
artmasına bağlı olarak iyileşme göstermiştir. Radyal yöndeki yüzey pürüzlülük
parametrelerine kıyasla teğet yönde iyileşmenin daha fazla olduğu
belirlenmiştir
Güneş Panellerinde Hibrit ve YSA Tabanlı Algoritmalar ile Güç Takibi
Authors: ÖZDEMİR Ayhan , Güngör Okan
Published: November 2018

Bu çalışmada, ilk olarak panel çıkış akım - gerilim büyüklüklerini
kullanan IC algoritmasını bulanık mantık yardımıyla değişken adım aralıklarına
sahip bir hibrit algoritma ile doğrudan MPPT yapılmaktadır. İkinci olarak çeşitli
sıcaklık ve radyasyon büyüklükleri ile YSA kullanılarak panel modeli elde
edilmiştir. Uygulamada bu model kullanılarak PID kontrolör aracılığıyla MPPT
yapılmıştır. Son olarak da bu iki algoritmanın değişken radyasyon, sıcaklık, yük
ve ön görülmeyen şartlar için karşılaştırmalı performansları benzetim ortamında
incelenmiştir.
Serum uric acid levels as a risk stratification tool in hypertensive pregnancy
Authors: Saldanha Cimona Lyn , Malik Sabha , Quraishi Azhar Un-Nisa
Published: November 2018

Background: Hypertensive disorders represent the most common medical complication of pregnancy affecting between 7-15% of all gestations and accounts for approximately a quarter of antenatal admissions.Methods: A case-control study was conducted over a period of 1 year. A total of 200 subjects were enrolled in the study and were divided into two groups; 100 cases and 100 controls. Serum uric acid levels were measured in cases and controls. The serum uric acid levels were correlated with the severity of PIH and maternal and fetal complications.Results: It was observed that the mean serum uric acid level in cases (5.0±1.74 mg/dl) was significantly higher compared to 2.66±0.39 mg/dl in controls. Serum uric acid levels also tended to increase with increasing severity of PIH, increasing from 3.69±0.95 mg/dl in gestational hypertension to 6.36±1.38mg/dl in severe PE. Maternal complications during antepartum and postpartum period were higher once SUA≥5mg/dl was taken as a cut-off. Protienuria(p=0.00), coagulopathy(p=0.007), need for blood/platelet transfusion(p=0.01) and eclampsia (p= 0.007) were significantly more. Similarly, complications were found to be higher, in babies born to mothers having serum uric acid more than 5 mg/dl compared to others in case group.Conclusions: Higher serum uric acid levels may indicate higher risk of progression to preeclampsia and development of adverse maternal/infant conditions.
Assistentes sociais de Belo Horizonte: esboço de um perfil profissional
Authors: Guiraldelli Reginaldo , Figueiredo Kênia Augusta , Maciel Fabrícia Cristina
Published: November 2018

Pesquisar o perfil profissional dos assistentes sociais na atualidade é essencial para compreendermos e situarmos a inserção destes profissionais no mundo do trabalho em tempos de reestruturação produtiva, desemprego estrutural e desmonte dos direitos sociais em um cenário de contra-reforma do Estado e expansão do ensino superior (público e privado) em todas as suas modalidades (presencial e a distância). Por isso, torna-se relevante analisar o perfil dos assistentes sociais tendo como ponto de partida considerações sobre a formação dos profissionais e os espaços ocupacionais que incorporam esta especialidade do trabalho coletivo. Assim, esse texto resulta de pesquisa qualitativa realizada por meio de entrevista com 209 assistentes sociais inseridos em diversos campos de trabalho do município de Belo Horizonte, com o objetivo de conhecer de forma aproximativa o perfil desses profissionais.
Ecos do silêncio: violência sexual denunciada no CREAS Mossoró-RN
Authors: Russo Gláucia Helena Araújo , Silva Hiago Trindade de Lira , Nogueira Jéssica Lima Rocha , Dantas Juliana Grasiela da Silva
Published: November 2018

No âmbito desse artigo buscamos analisar a violência sexual intrafamiliar contra crianças e adolescentes no município de Mossoró-RN, tendo como referência os resultados parciais da pesquisa intitulada: Sobre o (in)dizível: Violência intrafamiliar contra crianças e adolescentes em Mossoró-RN, na qual realizamos um levantamento dos casos atendidos pelo Centro de Referência Especializada em Assistência Social (CREAS), no período de 2010 a 2012.
Dispositivo da Velhice: o dito e o não dito na sua fabricação.
Authors: Giusti Patricia Haertel , Henning Paula Corrêa
Published: November 2018

O objetivo deste artigo é mostrar como constituímos um enunciado de velho-saudável, partindo da análise e discussão acerca de como o dispositivo da velhice é hoje operacionalizado na mídia impressa. Para isso apresentamos alguns elementos jurídicos, como o Estatuto do Idoso, formas de viver e praticar a velhice nos dias de hoje e, ainda, algumas reportagens de capa dos cadernos de saúde de dois jornais brasileiros. Essas trazem para reflexão enunciações sobre a velhice e o processo de envelhecimento, especialmente pautados pelo discurso da ciência médica, hoje focado nas ações de promoção da saúde e prolongamento da vida. Finalizamos a discussão mostrando como aquilo que está dito para a população de velhos e aquilo que está visível se entrelaçam na constituição de um dispositivo que precisa responder a uma urgência do século XX – dar conta de um país que envelhece.
Política pública, juventude e sustentabilidade
Authors: Fernandez Cristiane Bonfim , Rodrigues Débora Cristina Bandeira , Nunes Maísa Bruna de Almeida , Teles Maria Alcione Pereira
Published: November 2018

A questão ambiental e a discussão em torno da sustentabilidade têm ocupado espaço importante na agenda dos meios de comunicação, da sociedade civil e do governo, o que requer de diferentes estudiosos uma análise. Nesse sentido, este artigo desenvolve uma reflexão sobre a relação entre juventude, política pública para jovens e sustentabilidade. Trata-se de uma pesquisa bibliográfica. Além da literatura sobre o tema, o principal documento consultado foi a Política Nacional da Juventude.  Este estudo revelou os avanços das políticas públicas de juventude, particularmente a criação de coletivo jovens de meio ambiente e qualidade de vida. Constatou-se ainda que a discussão da sustentabilidade está presente principalmente quando aponta o eixo qualidade de vida na Política de Juventude e há uma orientação visando a preservação do meio ambiente para as gerações futuras.
Plano Colômbia e Iniciativa Mérida: uma análise à luz da Segurança Humana
Authors: Lyra Mariana
Published: November 2018

O texto traz uma análise do Plano Colômbia e da Iniciativa Mérida em termos de segurança humana, apresentando os desafios da atual política de Guerra às Drogas na América Latina para garantir a segurança das pessoas e sua contribuição para a diminuição drástica das condições de vida das populações locais.
O Banco Mundial e as Reformas da Previdência Social na América Latina
Authors: Magioni Mirella Januário
Published: November 2018

Neste artigo apresentamos a trajetória do Banco Mundial na sua aproximação com a política de Previdência Social, bem como sua evolução ao longo das décadas de 1980, 1990 e 2000. Partimos da premissa de que tal perspectiva não se apresentou de forma igual nessas três décadas, uma vez que as condições objetivas que a sustentam também se modificaram. Assim, a crise de endividamento dos países da América Latina na década de 1980, os ajustes estruturais, as reforma dos sistemas de repartição e o aumento da pobreza são processos dinâmicos em que o Banco Mundial atuou e ao mesmo tempo se modificou no decorrer dessa atuação.
Spatial Econometrics and GIS YouTube Playlist
Authors: Burkey Mark L.
Published: November 2018

This resource describes a website and playlist of YouTube videos using open source software (R, GeoDa, and QGIS) designed to help get scholars up and running with analyzing their own data. In the series sample data, handouts, code, and map files are provided. The course covers the basics of integrating data into a spatial data set, contiguity and spatial correlation, doing basic spatial regressions in GeoDa, and doing more sophisticated specification tests and regressions in R.
ОЦІНЮВАННЯ ЯКОСТІ БАНКІВСЬКИХ ПОСЛУГ НА ОСНОВІ ПІДХОДУ SERVQUAL: СУЧАСНА ІНТЕРПРЕТАЦІЯ
Authors: Leonov S. V. , Demkiv Yu. M. , Samusevych Ya. V.
Published: November 2018

У статті проведено аналіз репрезентативності окремих компонент оцінювання якості банківських послуг на основі існуючих емпіричних досліджень з визначення їх впливу на задоволення споживачів та ступеня пріоритетності для клієнтів банку. Запропоновано нову інтерпретацію підходу SERVQUAL з урахуванням важливості компонент та застосуванням методу семантичного диференціалу для оцінювання критеріїв споживачами банківських послуг.
НАГЛЯД ТА КОНТРОЛЬ ЗА ОРГАНАМИ МІСЦЕВОГО САМОВРЯДУВАННЯ В УКРАЇНІ: ТЕОРЕТИЧНІ ТА ЮРИДИЧНІ ПІДХОДИ ДО РОЗРОБКИ КОНЦЕПЦІЙ
Authors: Sychenko V. V. , Pugach Andriy , Molodchenko Tayisiya , Tarasenko Tetiana
Published: November 2018

Визначено теоретико-правову основу для розгляду сучасної системи нагляду органів місцевого самоврядування в Україні. Доведено, що українське законодавство у цій сфері орієнтоване на контроль за конституційною концепцією підзвітності органів місцевого самоврядування. Водночас зазначається, що правові підстави для організації чинної системи державного нагляду в цілому відповідають принципам адміністративного нагляду, викладеним у Європейській хартії місцевого самоврядування. Проте зазначається, що адміністративний нагляд не виявляє цілого комплексу питань, які потребують нагляду і контролю у процесі діяльності органів місцевого самоврядування та їхніх посадових осіб. Було підтверджено необхідність подальшого дослідження проблеми у зв’язку з питанням відповідальності органів місцевого самоврядування та посадових осіб.
FISCAL EFFICIENCY OF ADMINISTRATION OF DUTIES UKRAINE
Authors: Gontareva I. V. , Hutsul I. A. , Tkachyk F. A. , Miroshnik O. Yu.
Published: November 2018

In the current conditions of development of European integration processes and strengthening of role of international economic relations, a significant role is played by customs policy and its effective implementation in the context of administering duties. The fiscal and regulatory component of customs duties plays an important role in shaping the financial resources of the state and enhancing the customs security of Ukraine. The theoretical and organizational principles for administering duties have been outlined in the article. Fiscal analysis of the formation of budgetary resources at the expense of import and export duties has been carried out. The article states that import duty is a common tool for regulation of foreign economic activity, along with this it increases the price of goods and reduces its competitiveness.The forecasting of budget revenues from the duty for the near future has been performed. The coefficient of collection of import and export duties has been calculated and its dynamics has been highlighted.It has been found that customs payments are characterized by a regularity of revenues, as the population often needs the consumption of goods and services.The monitoring of the taxation of foreign economic activity in Ukraine made it possible to find out that the fiscal function of custom duty appears to be insignificant in relation to other tax payments, but the nature of customs administration is manifested in its regulatory influence. It should be noted that the policy in the field of customs taxation of consumption should be flexible and take into account the peculiarities of socio-economic development and the state of the consumer market in Ukraine.On the basis of identification of positive and negative features of the customs tax, measures to increase the efficiency of administration of customs duties to the budget have been formulated, among which, the main attention should be paid to simplifying customs clearance procedures, counteracting contraband and corruption facts, enhancing professional skills of the personnel capacities customs units of SFSof Ukraine and automating customs administration and regulation procedures.
ADVERSE INFLUENCE OF INVESTMENT CLIMATE ON INVESTMENT ATTRACTIVENESS OF UKRAINE
Authors: Furdychko L. Ye. , Pikhotska О. M.
Published: November 2018

The article deals with the main directions of state regulation of the investment climate in Ukraine, the question of becoming an investment attractiveness and investment climate. The analysis of dynamics of volume of direct foreign investments in the Ukrainian economy has been made, which made it possible to assess the investment climate of Ukraine at the present stage of development, to determine the reasons that cause an unfavorable investment climate and restrain economic development of the country. It was established, that investment resources are called to influence the economy and social sector of the country to transform it into an international space by searching for new sources of such resources for ensuring perspective development of Ukraine.The main factors influencing the investment climate and the reasons for the reduction of investment flows into the Ukrainian economy are analyzed and the problems encountered by the foreign and national investors are analyzed.It was emphasized, that effective development of industries of Ukrainian economy has a perspective in involving foreign investment resources and forming of the favorable investment climate. The attention was drawn to the fact, that the absence of subsequent reforms prevents the industries from involving the necessary investment into the durable production assets and for improving management skills with an aim to enhance the performance of production facilities.The index of investment attractiveness according to the version of the top managers of member companies of the European Business Association is analyzed.The investment attractiveness of Ukraine at the present stage of development was assessed. It was mentioned that slowness of social and economic reforms, ineffective tax policy, high credit rates in financial and credit establishment, annexation of Crimea and military action in the Eastern Ukraine, bureaucracy in making administrative decisions, illegal trafficking and presence of “shadow” economy in the country — all these are problems, which deteriorate the investment climate in Ukraine and degrade its investment attractiveness.The article determines the ways of solving problems connected with the containment of investment development and proposes directions of improvement of the investment climate.
ЕВОЛЮЦІЯ БАЗОВИХ КОНЦЕПЦІЙ ВАРТІСНО-ОРІЄНТОВАНОГО УПРАВЛІННЯ
Authors: Ievdokymov V. V. , Valinkevich N. V. , Zavalii T. O.
Published: November 2018

Представлено історичні аспекти розвитку концепції вартісно-орієнтованого управління. За допомогою онлайн-сервісу «Google Books Ngram Viewer» визначено, що першим роком згадки словосполучення «Value Based Management» слід вважати 1975 рік, натомість словосполучення «Value-Based Management» з 1984-го. Основні етапи розвитку концепції вартісно-орієнтованого управління визначені в такій послідовності: створення моделі «Shareholder Value Added» (SVA); створення моделей «Economic Value Added» (EVA), «Market Value Added» (MVA), «Cash Flow Returnon Investment» (CFROI), «Cash Value Added» (CVA); адаптація консалтингових продуктів основних учасників ринку стратегічного консультування до нових ідей і посилення конкурентної боротьби за право управляти інвестиційною вартістю капіталу; поширення підходів вартісно-орієнтованого управління на діяльність фінансових аналітиків та їхню практику. Основний наголос зроблено на тому, що головну роль у виникненні концепції вартісно-орієнтованого управління відіграли провідні у світі консалтингові компанії, у практиці яких консалтинг у сфері управління вартістю компаній — один з основних напрямів діяльності. Виокремлено два основні підходи в еволюції досліджуваної концепції. Першим у ході становлення вартісно-орієнтованого управління слід вважати підхід, що дістав назву управління акціонерною вартістю» (Shareholder Value Management). Основним аргументом противників цього підходу стало твердження, що абсолютна концентрація на зростанні акціонерної вартості не вирішує таких нагальних питань, як проблеми зайнятості, навколишнього середовища, етики в бізнесі. Той факт, що вартість компанії формується не тільки завдяки акціонерам і їхнього капіталу, а й завдяки іншим стейкхолдерам сприяв появі другого підходу — управління стейкхолдерською вартістю (Stakeholder-BasedManagement), що має за мету гармонізувати інтереси різних груп стейкхолдерів.
Isolasi dan Karakterisasi Bakteri Proteolitik yang Berasosiasi dengan Lamun Enhalus acoroides di Pantai Bama, Taman Nasional Baluran, Situbondo, Jawa Timur
[Isolation and Characterization Proteolytic Bacteria which is Associated with Sea Grass (Enhalus acoroides) in Bama Beach, Baluran National Park, Situbondo, East Java].
Authors: Rizaldi Rachmat , Setyantini Woro Hastuti , Sudarno Sudarno
Published: November 2018

AbstrakLamun adalah tumbuhan sejati yang hidup di perairan pantai yang kurang dimanfaatkan dalam bidang perikanan, selain sebagai bioindikator kualitas air laut. Beberapa mikroorganisme yang berasosiasi dengan lamun Enhalus acoroides antara lain benthos, kapang, bakteri dan plankton. Bakteri proteolitik merupakan bakteri yang mampu menghasilkan enzim protease. Enzim perotese merupakan enzim yang paling banyak digunakan dalam kehidupan. Bakteri merupakan sumber enzim yang paling banyak digunakan dibandingkan dengan tanaman dan hewan. Tujuan penelitian ini adalah untuk mengetahui jenis isolat bakteri proteolitik yang berasosiasi dengan lamun Enhalus acoroides di Taman Nasional Baluran, Situbondo. Penelitian ini menggunakan metode survei dengan dianalisis secara deskriptif dengan bantuan tabel dan gambar. Hasil yang peroleh menunjukkan bahwa terdapat 12 isolat bakteri yang berasosisasi dengan lamun Enhalus acoroides. Terdapat empat isolat yang tergolong sebagai bakteri proteolitik karena mampu mendagradasi kasein dalam media TSA + 2% NaCL yang ditambah 1 % susu skim, tampak dari pembentukan zona bening. Pengamatan morfologi koloni dan sel serta pengujian biokimia dari keempat isolat (EA-1, EA-2, EA-9 dan EA-10) terdapat kesamaan karakteristik dengan empat genus bakteri berturut-turut yaitu Staphylococcus sp., Plesiomonas shigeloides, Bacillus sp., Pseudomonas sp.AbstractSeagrass is a true living plants underutilized coastal waters in the field of fisheries, as well as bio-indicators of the quality of sea water. Some microorganisms associated with seagrass Enhalus acoroides among others benthos, fungi, bacteria and plankton. Proteolytic bacteria are bacteria that are capable of producing the enzyme protease. Protease enzyme is an enzyme that is most widely used in life. Bacteria are a source of enzymes that are most widely used compared to plants and animals. The purpose of this study was to determine the type of proteolytic bacterial isolates associated with seagrass Enhalus acoroides in Baluran National Park, Situbondo. This study used survey method with descriptive analysis with tables and figures. The results obtained that there are 12 bacterial isolates associated with seagrass Enhalus acoroides. There are four isolates were classified as proteolytic bacteria because it can degrade casein in TSA media + 2 % NaCL plus 1% skim milk which is evidenced by the formation of clear zones. Observations colony morphology and cells, as well as testing of Biochemistry of the four isolates (EA-1, EA-2, EA-9 and EA-10), were obtained, with similar characteristics to the four genera of bacteria in a row as follows Staphylococcus sp., Plesiomonas shigeloides, Bacillus sp., Pseudomonas sp.
Prevalensi dan Derajat Infestasi Ektoparasit pada Udang Vaname (Litopenaeus vannamei) di Tambak Intensif dan Tradisional di Kabupaten Gresik
[ Prevalence and Degrees of Infestation Ectoparasite on White Shrimp (Litopenaeus vannamei) in Intensive and Extensive Cultivation System in Gresik]
Authors: Farras Abyan , Mahasri Gunanti , Suprapto Hari
Published: November 2018

AbstrakUdang putih (Litopenaeus vannamei) adalah komoditas unggulan budidaya yang memiliki harga yang signifikan pada pasar di seluruh dunia. Sepenuhnya permintaan udang, perlu perhatian serius dalam pembenihan vaname, dengan bertujuan untuk mendapatkan panen maksimal dan dapat memenuhi kebutuhan pasar. Tujuan penelitian ini untuk menentukan prevalensi dan derajat infestasi, serta mengetahui perbedaan prevalensi dan derajat infestasi ektoparasit pada udang vaname sistem intensif dan tradisional. Metode yang digunakan dalam penelitian ini menggunakan metode survei, yaitu metode pengamatan sistematis, faktual, dan akurat tentang fakta dan sifat populasi atau pada wilayah tertentu. Prevalensi ektoparasit yang menyerang udang putih di budidaya intensif 57,5% dan budidaya tradisional 56,6% dan dalam kategori sering (sering kali) tingkat infestasi rata - rata yang menginfeksi vaname putih dalam budidaya intensif adalah 76,56 (berat), sedangkan di budidaya tradisional adalah 43,78 (sedang). Hasil analisis data menunjukkan bahwa tidak ada perbedaan antara prevalensi budidaya intensif dan tradisional (p> 0,05), terdapat perbedaan tingkat infestasi ektoparasit antara prevalensi budidaya intensif dan tradisional                                                             Abstract White shrimp (Litopenaeus vannamei) is a species of cultivation and have important value in the worldwide market.Tofully a demand of shrimp, need for serious treatment in prawn hatchery vaname, with the aim that gets the maximum harvest and can fulfill a need market. The aims of this research to determine the prevalence and degree of infestation, as well as know the difference prevalence and degree of infestation ectoparasite on shrimps vaname which are in intensive and extensive cultivation. The method used in this study using survey methods, that is methods to make observation systematical, factual, and accurate about the fact and the nature of the population or to a definite region. The prevalence of ectoparasite that infests white shrimp in intensive cultivation is 57,5% and in traditional cultivation is 56,6% and in category frequently (often times). The average degree of infestation that infects white vaname in intensive cultivation is 76,56 (heavy), while in the traditional cultivation is 43,78 (medium). The results analysis of the data show that there is no difference between the prevalence of intensive and traditional cultivation (p > 0,05), there was difference infestation degree of ectoparasite between the prevalence of intensive and traditional cultivation.
Kajian Potensi Ekstrak Daun Pepaya (Carica Papaya L) terhadap Immunitas Non Spesifik Udang Vaname (Litopenaeus vannamei)
[Potential Study of Papaya Leaf Extract (Carica papaya l) against Non-Specific Immunity of Lithopenaeus vannamei]
Authors: Monica Mona , Wardiyanto Wardiyanto , Susanti Oktora
Published: November 2018

AbstrakDalam berbudidaya udang vaname terdapat kendala yang harus dihadapi, salah satunya adalah serangan penyakit. Upaya pencegahan dan penanggulangan dapat berupa pemberian imunostimulan menggunakan ekstrak daun pepaya yang diaplikasikan dengan cara perendaman. Tujuan penelitian ini adalah mempelajari pengaruh ekstrak daun pepaya terhadap imunitas non spesifik udang vaname (Litopenaeus vannamei). Penelitian ini dilaksanakan pada bulan juli-agustus dengan menggunakan empat perlakuan yang diterapkan yaitu perlakuan A (0 mg/l ekstrak daun pepaya), B (10 mg/l ekstrak daun pepaya), C (20 mg/l ekstrak daun pepaya), dan D (30 mg/l ekstrak daun pepaya). Parameter yang diuji yaitu total hemocyte count, aktivitas fagositosis, indeks fagositosis. Hasil penelitian menunjukkan bahwa ekstrak daun pepaya sebagai imunostimulan dapat meningkatkan respon imun udang vaname. Konsentrasi terbaik yaitu 30 mg/l.                                                              AbstractIn the activity of cultivating shrimp, there are some obstacles that must be faced such as diseases attack. One of the efforts that we can do as the prevention and solve the problem in shrimp that us through the giving of immunostimulant using papaya leaf extract which applicated with dipping method. This research aimed to study the effect of papaya leaf extract against the nonspecific immunity of vannamei shrimp (Litopenaeus vannamei). This research was carried out in July-August which applied with 4 treatments, treatment A (0 mg/l papaya leaf extract), B ( 10 mg/l papaya leaf extract), C (20 mg/l papaya leaf extract), and D (30 mg/l papaya leaf extract). The parameters used in this research were total hemocyte count, phagocytosis activity, and phagocytosis index. The result showed that papaya leaf extract as immunostimulant can improve the immune response of vannamei shrimp. The treatment with 30 mg/l is the best concentration.
EFFICACY OF HYPOFRACTIONATED ADJUVANT RADIATION THERAPY IN PATIENTS WITH OPERABLE BREAST CANCER
Authors: Afonin G. V. , Ragulin Y. A. , Gulidov I. А. , Beketov Е. E. , Kaprin A. D.
Published: November 2018

The purpose of the studywas to evaluate the efficacy and safety of hypofractionated postoperative radiation therapy (2.7 Gy per fraction in 15 fractions to a total dose of 40.5 Gy) in comparison with the standard fractionation regimen.

Material and methods.The study included 321 patients diagnosed with stage I–IIIA breast cancer treated in the A. Tsyb Medical Radiological Research Center from 2013 to 2017. The patients were divided into two groups. Group I patients received hypofractionated postoperative radiotherapy at a total dose of 40.5 Gy in 15 fractions with Gy 2.7 Gy/fraction (n=223). Group II patients received conventional radiotherapy at a total dose of 50 Gy in 25 fractions with 2 Gy/fraction (n=98). Both groups were comparable in terms of the stage of the disease and molecular subtype of the tumor. The statistical analysis of the main characteristics of the studied regimens was carried out.

Results.The analysis revealed no significant differences in the overall survival (OS) and disease-free survival (DFS) between two groups. The frequency of acute radiation-induced complications (grade 1 and 2) in Groups I and II were 79 % and 84 %, respectively. Late radiation-induced side effects were observed less frequently in patients treated with hypofractionated postoperative radiotherapy than in the control group patients (23 % versus 43 %, p<0.01). Severe post-radiation damage to normal tissues was not found. The extent of surgery did not affect the long-term treatment outcomes.

Conclusion.Comparison of hypofractionated radiotherapy with conventional radiotherapy in breast cancer patients demonstrated the superiority of hypofractionated radiotherapy regimen in terms of late toxicity and economic profitability. Further studies of accelerated fractionated postoperative radiotherapy are required to improve the treatment outcomes in breast cancer patients.
THE FIRST EXPERIENCE OF USING LAPAROSCOPIC GAMMA PROBE FOR INTRAOPERATIVE VISUALIZATION OF SENTINEL LYMPH NODES IN GYNECOLOGICAL CANCER
Authors: Ochirov M. O. , Kolomiets L. A. , Chernov V. I. , Sinilkin I. G. , Chernyshova A. L. , Villert A. B. , Molchanov S. V. , Churuksaeva O. N. , Kishkina A. Yu.
Published: November 2018

Visualization of sentinel lymph nodes (SLN) is now widely accepted for lymph node (LN) detection using a radioactive lymphotropic trace. Preoperative lymphoscintigraphy with intraoperative lymphatic mapping under gamma detecting probe guidance proved to be an easy and reliable method for SLN detection.

Material and methods.In this article we present our experience in using laparoscopic gamma-probe for intraoperative visualization of sentinel lymph nodes in gynecological cancer.

Results.Intraoperative visualization of sentinel lymph nodes in young cervical cancer patients and in patients with stage I endometrial cancer allowed us to perform radical surgery with personalization of the extent of lymph node dissection, especially for patients with low and intermediate risks of lymphogenic metastasis.
RESECTION OF TRACHEAL BIFURCATION IN TREATMENT OF NON-SMALL CELL LUNG CANCER (LITERATURE REVIEW)
Authors: Dadyev I. A. , Davydov М. M. , Chekini A. K. , Anisimov M. A. , Gerasimov S. S. , Shogenov M. S. , Akhmedov P. I. , Kanzapetov M. R.
Published: November 2018

Over the past few years, significant advances in surgical and anesthetic techniques as well as appropriate selection of patients have led to an improvement in the immediate and long-term treatment outcomes in patients with non-small cell lung cancer with involvement of tracheal bifurcation. In accordance with the current selection criteria, patients with contralateral lymph node metastases (lung root, aortic window, paratracheal area) require chemotherapy or chemoradiotherapy with subsequent estimation of follow-up and treatment strategy. Surgeries with resection of tracheobronchial bifurcation are considered technically complicated, and they should be performed in carefully selected lung cancer patients and only in specialized centers with extensive experience. It allows the incidence of intra-and postoperative complications to be significantly reduced.
Cooling phonon modes of a Bose condensate with uniform few body losses
Authors: Bouchoule Isabelle , Schemmer Max , Henkel Carsten
Published: November 2018

We present a general analysis of the cooling produced by losses on
condensates or quasi-condensates. We study how the occupations of the
collective phonon modes evolve in time, assuming that the loss process
is slow enough so that each mode adiabatically follows the decrease of
the mean density. The theory is valid for any loss process whose rate is
proportional to the jjth
power of the density, but otherwise spatially uniform. We cover both
homogeneous gases and systems confined in a smooth potential. For a
low-dimensional gas, we can take into account the modified equation of
state due to the broadening of the cloud width along the tightly
confined directions, which occurs for large interactions. We find that
at large times, the temperature decreases proportionally to the energy
scale mc^2mc2,
where mm
is the mass of the particles and cc
the sound velocity. We compute the asymptotic ratio of these two
quantities for different limiting cases: a homogeneous gas in any
dimension and a one-dimensional gas in a harmonic trap.
Primera época - Año V, Número 13, enero 2003
Authors: De San Luis Revista de El Colegio
Published: November 2018

Este número corresponde a la primera época de la Revista de El Colegio de San Luis, denominado VETAS.
Electrochemical Detectors in Liquid Chromatography: Recent Trends in Pharmaceutical and Biomedical Analysis
Authors: Kauffmann Jean-Michel , Bakirhan Nurgul K. , Bozal-Palabiyik Burcin , Uslu Bengi , Rodriguez Gomez Rocio , Vandeput Marie , A. Ozkan Sibel
Published: November 2018

Liquid chromatography (LC) coupled to an electrochemical (EC) detector is a
complementary analytical tool compared to LC coupled with optical or mass spectrometry
detectors (LC-MS). LC-EC can be applied to the determination of molecules difficult to be
analyzed by other commercially available detectors. New EC detector design and new
working electrode material have extended the scope of application in the field of pharmaceutical
compounds analysis. Combining EC with LC-MS offers additional advantages
compared to optical detectors in terms of drug stability and drug metabolism mimicry studies.
Selected literature devoted to pharmacologically active compounds in their dosage
forms, herbal drugs in natural products, drug residues in feed and/or in biological samples
are reported in this review.
Plant Aquaporins: Diversity, Evolution and Biotechnological Applications
Authors: Bezerra-Neto João P. , de Araújo Flávia Czekalski , Ferreira-Neto José R.C. , da Silva Manassés D. , Pandolfi Valesca , Aburjaile Flavia F. , Sakamoto Tetsu , de Oliveira Silva Roberta L. , Kido Ederson A. , Barbosa Amorim Lidiane L. , Ortega José M. , Benko-Iseppon Ana M.
Published: November 2018

The plasma membrane forms a permeable barrier that separates the cytoplasm from the external environment, defining the physical and chemical limits in each cell in all organisms. The movement of molecules and ions into and out of cells is controlled by the plasma membrane as a critical process for cell stability and survival, maintaining essential differences between the composition of the extracellular fluid and the cytosol. In this process aquaporins (AQPs) figure as important actors, comprising highly conserved membrane proteins that carry water, glycerol and other hydrophilic molecules through biomembranes, including the cell wall and membranes of cytoplasmic organelles. While mammals have 15 types of AQPs described so far (displaying 18 paralogs), a single plant species can present more than 120 isoforms, providing transport of different types of solutes. Such aquaporins may be present in the whole plant or can be associated with different tissues or situations, including biotic and especially abiotic stresses, such as drought, salinity or tolerance to soils rich in heavy metals, for instance. The present review addresses several aspects of plant aquaporins, from their structure, classification, and function, to in silico methodologies for their analysis and identification in transcriptomes and genomes. Aspects of evolution and diversification of AQPs (with a focus on plants) are approached for the first time with the aid of the LCA (Last Common Ancestor) analysis. Finally, the main practical applications involving the use of AQPs are discussed, including patents and future perspectives involving this important protein family.