bluuebunny/crossref_metadata_2025 huggingface dataset:
Función ovárica y respuesta a la sincronización del estro en ganado Criollo en México. Revisión
Authors: Pérez-Ruiz Elizabeth , Quezada-Casasola Andrés , Carrera-Chávez José María , Álvarez-Holguín Alan , Ochoa-Rivero Jesús Manuel , Chávez-Ruiz Manuel Gustavo , Roman-Ponce Sergio Ivan
Published: May 2022

Hoy en día, las biotecnologías reproductivas han hecho posible conservar y aprovechar los recursos zoogenéticos. Una de estas tecnologías son los programas de sincronización de estros, mismos que permiten programar la época para el empadre acorde a la disponibilidad de forraje o el nacimiento de los becerros por fines comerciales. Otra aplicación es la reducción del intervalo parto primera ovulación, mediante protocolos que facilitan el uso de inseminación artificial. Los bovinos criollos son un recurso genético valioso, debido a su rusticidad y adaptabilidad a condiciones ambientales difíciles; son resistentes a parásitos, aprovechan los recursos forrajeros disponibles y se reproducen en sistemas con poca o nula suplementación. En México, los primeros estudios de sincronización de bovinos criollos sugieren que las vacas criollas no responden adecuadamente a los protocolos hormonales y se obtienen porcentajes de gestación inferiores a los obtenidos en otras razas. Lo anterior, dio origen a una serie de investigaciones en fisiología reproductiva y uso de biotecnologías en ganado criollo. El objetivo de esta revisión es recabar la información existente sobre el uso de protocolos de sincronización de estros y ovulación en bovinos criollos de México; con la finalidad de poder identificar las líneas de investigación necesarias para el desarrollo de protocolos de sincronización de estros y ovulación adecuados para el ganado criollo.
Quantum and Classical Bayesian Agents
Authors: DeBrota John B. , Love Peter J.
Published: May 2022

We describe a general approach to modeling rational decision-making agents who adopt either quantum or classical mechanics based on the Quantum Bayesian (QBist) approach to quantum theory. With the additional ingredient of a scheme by which the properties of one agent may influence another, we arrive at a flexible framework for treating multiple interacting quantum and classical Bayesian agents. We present simulations in several settings to illustrate our construction: quantum and classical agents receiving signals from an exogenous source, two interacting classical agents, two interacting quantum agents, and interactions between classical and quantum agents. A consistent treatment of multiple interacting users of quantum theory may allow us to properly interpret existing multi-agent protocols and could suggest new approaches in other areas such as quantum algorithm design.
Poetry and Tax Statute: Translation as Interpretation
Authors:   University of Western Australia, Sharkey Nolan , Tkachenko Tatiana
Published: May 2022

This paper applies the literary critique of translating poetry to the field of translating statute to raise significant constitutional and practical issues. The field of focus is taxation law, an area notable for its complexity and intricacy in a large number of countries. A linguistic argument is made that the demands that are made on the words of tax law parallel those made in poetry and this necessarily creates a demand for interpretation on the part of users of the law. This aspect of interpretation is then considered in situations that demand the translation of foreign and a number of constitutional and practical issues are highlighted in relation to the role of the translator. The issues raised in the paper are of significant importance in an increasingly globalised international tax world where statutes written in very different languages are called upon to interact with one another.
European Small Claims Procedure: Is It So Simplified?
Authors:   University of Latvia, Kacevska Inga
Published: May 2022

The European Small Claims Procedure is an alternative to national similar procedures and intended to simplify and speed up the litigation in the cross-border cases. The Regulation has proven to have a potential in settling small claims’ disputes within European Union. However, the more frequently the Regulation is applied in Member States, the more challenging issues are found, making application of Regulation not as simple as it might appear. This article analyses some of those issues arising from the practical application of the Regulation. Firstly, it is discussed whether the concept contained in Regulation “other claim” may also include a supplementary declaratory claim (not only the claim that can be expressed in money). Secondly, it is further argued that the Regulation should be amended to have a more uniform and autonomous character, as much as possible limiting the reference to the national procedural rules. For instance, in accordance to Regulation, the concept “clearly unfounded” claim shall be determined pursuant to national law. However, in some jurisdictions (i.e., Latvia) such concept is unknown. There is a need for further reform of the Regulation to introduce a new level to facilitate its popularity, effectiveness and uniform application in Member States.
Control Over Legality of Parliamentary Elections in a State Governed by the Rule of Law
Authors:   Faculty of Law, University of Latvia, Rodina Anita , Karklina Annija
Published: May 2022

The article examines the genesis of control over the legality of the Saeima (the parliament of the Republic of Latvia) elections, particularly focusing on the judicial review of the Saeima elections. The particularities of the control over elections, which differentiate them from typical administrative legal proceedings, are highlighted in the publication. The article presents findings of the case law regarding the limits of controlling the legality of elections and the cases when the court could revoke a decision by the Central Election Commission on approving the results of the Saeima elections. In view of the fact that sometimes the regulation set out in the Saeima Election Law has been criticised in the Latvian legal science, namely, that the legality of elections is controlled by the Department of Administrative Cases of the Supreme Court’s Senate rather than the Constitutional Court, the authors examine the models of controlling the legality of elections found in various states and provide their assessment of whether the control functions should be transferred into the jurisdiction of the Latvian Constitutional Court.
Foundation Atrocities and Public History: The Role of Lawyers in Finding Truth
Authors:   University of Western Australia, Sharkey Nolan , Muzyka Tetiana ,   Ivano-Frankivsk National Medical University,
Published: May 2022

History provides the basis for nations’ existence. Yet, history is capable of telling different stories in relation to the same events. It is also open to manipulation and distortion. More so than ever, this is the case with the easy availability and cross border reach of many forms of media. In addition, the concept of public history recognises that representations of history are not made solely by professional historians. The conclusion that must be reached from this is that history is open to contesting and it is not necessarily a fair contest favouring accuracy. This paper argues that law and legal scholars can play a role in settling significant historical disputes by applying the rigour of legal dispute settlement institutions. Consideration of evidence and narrowing arguments to relevant issues are of significant worth. These possibilities are illustrated through the debates surrounding two significant atrocities of history, the Great Irish Famine and the Ukrainian Holodomor. Both events have a critical place in the nation-building of the Irish and the Ukrainians, yet the debate rages on as to whether they may or may not be genocide. We review the historical issues and the genocide issue and suggest that legal scholars rather than historians may assist in settling rather than perpetuating the disputes.
O resgate das urnas: o histórico da luta munduruku contra a morte de seus lugares sagrados
Authors: Loures Rosamaria Santana Paes , Moreira Fernanda Cristina
Published: May 2022

Nos últimos anos, com o avanço dos grandes projetos de desenvolvimento sobre a bacia do rio Tapajós, povos indígenas e comunidades tradicionais vêm testemunhando a destruição de paisagens que compõem sua territorialidade. O povo Munduruku deparou-se com a destruição de seus Ipi Cekay’Piat (“lugares sagrados”) e com a retirada de Itiğ’a (urnas funerárias) durante a construção de usinas hidrelétricas no rio Teles Pires, iniciada em 2012. Em face das tragédias provocadas por essa interferência em lugares onde não se deve mexer, os Munduruku que vivem em Terras Indígenas no alto e médio Tapajós foram convocados por wamõat (pajés) e espíritos para atuarem em uma batalha contra a aniquilação de seus mundos. O artigo pretende apresentar recentes composições cosmológicas, escatológicas e rituais emergentes nas ocupações do canteiro de obras da Usina Hidrelétrica São Manoel, no rio Teles Pires e no resgate das Itiğ’a Wuyjuyū (urnas funerárias Munduruku) do Museu de História Natural de Alta Floresta (MT).
Precificando a dignidade humana no tribunal: os planos de saúde e as indenizações por danos morais
Authors: Bähre Erik
Published: May 2022

Clientes de planos de saúde processam suas seguradoras por essas empresas se recusarem a autorizar algum tratamento ou por fraude. Eles reivindicam juridicamente, com sucesso, que as seguradoras violam sua dignidade humana e que, portanto, devem pagar por danos morais. Alegações de danos morais não são feitas contra o Estado, que é o responsável pelo Sistema Único de Saúde (SUS). Isto significa que os tribunais estabelecem que o sofrimento e a dignidade humana significam uma coisa quando relacionados a uma companhia privada e outra quando se trata do Estado. Este estudo visa explorar a noção substantiva e legal da dignidade para demonstrar que a compensação financeira pelo sofrimento e pelas violações de dignidade é parte de um regime de valores. Esse regime molda a comensurabilidade da dignidade com o dinheiro e está ancorado em narrativas pessoais e em procedimentos legais, assim como nas expectativas do Estado e do mercado. Portanto, pacientes, que são também consumidores, são empoderados com uma dignidade humana que tem tanto um valor moral quanto um valor monetário.
Fofoca e relações entre parentes: um estudo etnográfico junto aos kariri-xocó
Authors: Santana Maiara Damasceno da Silva
Published: May 2022

Este artigo tem por objetivo compreender os processos de produção, reprodução e atualização das relações parentais entre os(as) Kariri-Xocó, comunidade indígena localizada no município de Porto Real do Colégio (AL), no vale do São Francisco. Centrado na temática da fofoca, aborda o papel que tal prática desempenha tanto no que se refere especificamente à produção de conflitos quanto à configuração das dinâmicas sociais em sentido mais amplo. Com base numa perspectiva etnográfica, o trabalho descreve e analisa alguns aspectos da gramática que estrutura as relações de parentesco locais, mostrando como, a depender da valoração que lhe é socialmente atribuída (isto é, se considerada boa ou ruim), a fofoca pode contribuir, seja para o espessamento ou a diluição de relacionalidades, seja para a dinamicidade, a reprodução e a atualização diária das relações.
“Vai além do nomadismo”: processos identitários, povos ciganos e o Estado na prática legislativa
Authors: Silva Phillipe Cupertino Salloum e , Figueira Luiz Eduardo de Vasconcellos
Published: May 2022

Este trabalho é uma descrição e análise das movimentações políticas e das discussões sobre os direitos dos povos ciganos no Congresso Nacional. Por meio do trabalho de campo, que envolveu levantamentos documentais e observação participante, compilamos e interpretamos os dados etnográficos, produzidos entre 2011 e 2020, à luz dos estudos envolvendo processos identitários, cultura e a questão cigana. O objetivo foi compreender os sentidos, os usos políticos e o que está em jogo acerca da condição cigana tomando como base a tramitação do Projeto de Lei n° 248, de 20151, que propõe a instituição do Estatuto do Cigano. Nota-se que o processo político do Estatuto não se restringe ao reconhecimento dos direitos dos povos ciganos e à previsão de políticas públicas. Culmina também na própria constituição do “sujeito cigano”, que se dá mediante um impulso dicotômico no qual ele experimenta seu processo de subjetivação, num jogo relacional entre forças e tensionamentos.
“Um governo dedicado ao homem comum e seus valores”: a cultura como objeto da política na gestão Bolsonaro
Authors: Cid Gabriel da Silva Vidal , Domingues João Luiz Pereira , Paula Leandro de
Published: May 2022

Inspirado pelos estudos em antropologia das políticas públicas, o artigo discute sentidos impressos pelo governo de Jair Bolsonaro à gestão do setor produtivo da cultura. O objetivo é demonstrar a formulação de um sujeito ideal a quem seria destinado o conteúdo da política pública, e lançar luz sobre conflitos que essa operação instala em relação a categorias e circuitos interacionais que pautaram historicamente a governamentalidade da área. Investigamos essa problemática tendo como referência dois atores-chave da Secretaria Especial de Cultura do governo federal, nativos de uma cena que se propõe a disputar os termos do debate público sobre as políticas para o setor. Com base na análise da formação de contrapúblicos, discutimos a atitude litigante que marca a produção da cultura como objeto da política no quadro do governo Bolsonaro.
Apresentação: “O certo é saber que o certo é certo” ou “o inferno são os outros”: conflitos (d)e representações em um mundo dividido
Authors: Silva Edilson Márcio Almeida da , Silva Emanuel Freitas da
Published: May 2022

Tendo como pano de fundo a propalada polarização político-ideológica vigente em nosso país, este dossiê temático tem por objetivo explorar discussões teóricas e etnográficas que enfoquem situações conflitivas sucedidas em diferentes contextos empíricos tanto no Brasil como no exterior. Com a seleção dos seis artigos que o compõem, buscou-se coligir trabalhos que, por meio de múltiplos e variados caminhos, se dedicassem não só à compreensão da natureza dos conflitos, mas também à discussão das suas respectivas formas de manifestação, administração, publicização e/ou (in)visibilização, o que levou os autores a descreverem e a analisarem os processos de produção de representações acerca das disputas em jogo, as estratégias então mobilizadas para se sagrar vencedor, bem como os efeitos práticos e simbólicos que os acompanham enquanto expressão do que se convencionou chamar construção social da realidade.
Vidas represadas: apuntes sobre los efectos de la implementación de la Hidroeléctrica Ituango en el Cañón del Cauca (Colombia)
Authors: Reyes Ángela Jasmín Fonseca , Silva Edilson Márcio Almeida da
Published: May 2022

Ciertos ríos, además de ser fenómenos naturales, cuentan con importantes dimensiones simbólicas que pueden ser leídas de diferentes maneras. Con respecto al río Cauca – uno de los más importantes cuerpos de agua de Colombia – los sentidos y significados que se construyen están mediados por discursos y prácticas que se tornan conflictivos ante las drásticas transformaciones generadas a partir de la construcción de la Hidroeléctrica Ituango, el mayor proyecto energético que actualmente se ejecuta en el país. Por tanto, en este texto proponemos una discusión sobre lo que podría denominarse una disputa de representaciones acerca del río Cauca en la región del Cañón del Cauca (Antioquia), examinando la forma como diferentes actores interpretan sus transformaciones a través del tiempo, considerándose, sobre todo, la construcción de este megaproyecto. Para tal fin nos aproximaremos a las prácticas de Estado y las nociones de desarrollo accionadas tanto por sus idealizadores y ejecutores como por las comunidades que se identifican como afectadas por este.
Social media content analysis of electronic cigarette information: Implications for public health ethics – A Brief Report
Authors: Sarwar Evangel , Moore Champagne , Corral Karina , Becerra Monideepa
Published: May 2022

The purpose of this study was to conduct a social media analysis on content related to electronic cigarettes, especially the validity of the information, audience engagement, and emergent ethical issues of health and related information on such a platform. Our results show a majority of the videos on social media platform analyzed were from individuals or organizations for marketing purposes, thus demonstrating a significant gap of needed public health driven content. We further present unique characteristics of popular videos, such as duration, comments, and like to dislike ratios that public health program can mimic to gain acceptance for anti-tobacco initiatives. The lack of information regulation on validity further raises several ethical concerns and we provide recommendations for actions to ensure the audience of such social media platform receive experience an-unbiased view of electronic cigarettes and associated outcomes.
Információ a piaci hangulatról
Authors: Póra András
Published: May 2022

A befektetések narratívája számos változáson ment keresztül az utóbbi száz évben, hiszen a hangulati és technikai alapú kereskedést a 20. század második felében a hatékony piacok elmélete gyakorlatilag eltüntette a főáram narratívájából. Később a viselkedési közgazdaságtan és pénzügyek előtérbe kerülésével ez a trend megfordult: a megközelítés mára ismét a tankönyvek részévé vált. A tanulmány elsőként ismerteti a folyamatot, amelynek keretében a befektetések narratívája visszatért a kezdeti értelmezéshez. Ezt követően a tőzsdei hangulat legkirívóbb kilengései, a buborékok, az ezekről alkotott elméletek kerülnek sorra a GameStop-jelenséget mint esettanulmányt szemléltetve. Végül az ezek észlelésére leggyakrabban használt tőzsdei hangulati indikátorok áttekintő összefoglalása következik. Utóbbira még nincs példa a szakirodalomban, ez adja a vizsgálódás újdonságértékét. Következtetésként elmondható: a közösségi média és a kereskedés demokratizálódása miatt a jövőben is megkerülhetetlen lesz a tőzsdei „információs társadalom” hangulatának mérése, elemzése és kutatása.
A case of cryptosporidial gastroduodenitis and wasting syndrome in an adolescent with advanced AIDS
Authors: Darazam Ilad Alavi , Zerehpoosh Farahnaz Bidari , Rabiei Mohammad Mahdi , Gharehbagh Farid Javandoust , Lotfollahi Legha , Shoushtari Maryam Taleb
Published: May 2022

Cryptosporidium causes watery diarrhea, despite the normal population it
might prolonged and life threatening in severely immunocompromised
individuals. In the current study, we reported Cryptosporidium
gastroduodenitis in 17 years old female with HIV (human immunodeficiency
virus).
Outcomes of expanded polytetrafluoroethylene pericardial membrane implantation in left ventricular assist device explantation and heart transplantation
Authors: R Kevin An , Christakis Nicole , Jegatheeswaran Anusha , Cusimano Robert , Rao Vivek , Badiwala Mitesh , Yau Terrence
Published: May 2022

Objectives Redo sternotomy and explantation of left ventricular
assist devices (LVAD) for heart transplantation (HT) involve prolonged
dissection, potential injury to mediastinal structures and/or bleeding.
Our study compared a complete expanded polytetrafluoroethylene (ePTFE)
wrap versus minimal or no ePTFE during LVAD implantation, on outcomes of
subsequent HT. Methods Between July 2005 and July 2018, 84
patients underwent a LVAD implant and later underwent HT. Thirty
patients received a complete ePTFE wrap during LVAD implantation (Group
1), and 54 patients received either a sheet of ePTFE placed in the
anterior mediastinum or no ePTFE (Group 2). Results Baseline
characteristics were similar between Groups 1 and 2. Surgeons reported
subjective improvements in speed, predictability and safety of
dissection with complete ePTFE compared with minimal or no ePTFE. Time
from incision to initiation of cardiopulmonary bypass (CPB) were similar
between groups (97±38 min vs 89±29 min, p=0.3). Injury to mediastinal
structures during the dissection was similar between groups (10% vs
11%, p>0.9). While surgeons reported less intraoperative
bleeding in Group 1 (43% vs 61%), this trend did not reach
significance (p=0.1). In-hospital mortality, ICU length of stay and
hospital length of stay were similar between both groups.
Conclusions In patients undergoing LVAD explant-HT, there was a
trend towards reduced surgeon reported intraoperative bleeding with
ePTFE placement. Despite qualitatively reported greater ease and speed
of mediastinal dissection with ePTFE membrane placement, time to
initiation of CPB did not differ, likely because surgeons remained
cautious, allowing extra time for unanticipated difficulties.
FcRn-targeting and ROS-responsive Fedratinib-incorporated Nanoparticles Alleviate Asthma by Inducing Eosinophil Apoptosis
Authors: Sun Weimin , SONG Shijie , LI Guangmeng , ZHOU linghui , XIE Junmou , GUO Yuhe , ZENG Jun , Zhang Junyan , LI Linmei , Yan Jie , SHUAI Xintao , TAO Ailin
Published: May 2022

Background: Reducing the number of airway eosinophils is
critical for treating eosinophilic asthma. The JAK2-STATs pathway is
essential for myelopoiesis of eosinophils and production of type I and
II cytokines, and therefore can be a novel target for intervention of
eosinophilic asthma. Here, we aimed to demonstrate the
apoptosis-inducing potential of Fedratinib (FDTN), a JAK2-specific
inhibitor, and test the efficacy of the ROS-responsive, FcRn-targeting
and FDTN-caged nanoparticles on eosinophilic asthma alleviation.
Methods: The apoptosis-inducing potential of FDTN in
eosinophils from asthma patients was assessed by flow cytometry, and
light and electron microscopy. FDTN-caged nanoparticles (NPs-FDTN) were
designed to ROS responsive and modified with Fc portion of IgG through
the avidin-biotin interaction. The biological availability of NPs-FDTN
was assembled via biochemical and immunological analysis, and the
therapeutic effects were investigated in eosinophilic asthma model mice
by comparing free FDTN and budesonide treatment. Results: FDTN
blocked the JAK2/STAT5 pathway and activated the intrinsic pathway of
apoptosis in eosinophils in a concentration-dependent manner. NPs-FDTN
crossed the epithelial barrier via the Fc/FcRn-mediated transcytosis,
bypassed the lysosome and entered the inflammatory microenvironment.
Caged FDTN was released from the nanoparticles in the presence of ROS.
Compared to free FDTN, the residence time of FDTN in the lung parenchyma
was prolonged and the therapeutic effects were improved when delivered
in nanoparticles. Conclusion: Ros-responsive, FcRn-targeting
and FDTN-caged nanoparticles overcame the airway epithelial barrier and
improved the bioavailability on eosinophil apoptosis. This study
provides a fancy and safe therapeutic strategy for treatment of
eosinophilic asthma.
Effects of straw returning and nitrogen addition on soil quality and physicochemical characteristics of coastal saline soil: A field study of 4 consecutive wheat-maize cycles
Authors: Xie Wenjun , Yang Hongjun , Xia Jiangbao , Wei Shoucai , Cui Qian , Shao Pengshuai , Sun Jingkuan , Dong Kaikai , Qi Xingchao
Published: May 2022

The effects of different straw returning and nitrogen addition levels on
soil quality are important for proper coastal saline soil remediation.
Two maize/wheat straw returning levels (1.0 × 10 kg
ha (2S) and 5.0 × 10 kg ha
(S)) and three inorganic nitrogen addition levels
(300 kg ha (N2), 150 kg ha (N)
and 75 kg ha (N1/2))—were studied, with 150 kg ha
inorganic nitrogen and without straw addition
treatment as the control (CK), to elucidate the response of soil
physical and chemical properties to the two factors. Dry-sieving
technique was applied to fractionate the soils into silt-plus-clay
particles (< 0.053 mm, CS), microaggregates (0.053–0.25 mm,
MI), small macroaggregates (0.25–2.0 mm, SM), and large macroaggregates
(> 2 mm, LM). After four consecutive wheat-maize cycles,
different straw and N fertilizer treatments obviously decreased the
salinity contents, increased the total nutrient contents, and optimized
the soil structure of the saline soil. The saline soil reclamation
effects showed significant distinctions among the different straw and N
fertilizer treatments. The 2SN2 treatment displayed the greatest effects
in regard to decreasing salinity, increasing the total soil nutrient
contents and optimizing the soil structure, which resulted in the best
remediation effect. Straw returning play a major role in decreasing soil
salinity and enhancing saline soil aggregate formation. N fertilizer
addition supplies rich nutrients for straw decomposition, and promotes
soil microbial growth and reproduction, which brought about C
sequestration in coastal saline soil. During the coastal saline soil
remediation process in the Yellow River Delta, it is suggested to
prioritize straw returning and moderate N fertilizer addition, and live
together with moderate P fertilizer application.
The roles of divergent and parallel molecular evolution contributing to thermal adaptive strategies in trees
Authors: W Collin Ahrens , Watson-Lazowski Alexander , Huang Guomin , Tissue David , Rymer Paul
Published: May 2022

Local adaptation is a major driver of biological diversity, and related
species may develop analogous (parallel evolution) or alternative
(divergent evolution) solutions to similar ecological challenges. We
expect these adaptive solutions between closely related organisms would
culminate in both phenotypic and genotypic signals. In this study, we
employ a reciprocal transplant, glasshouse experiment with two
Eucalyptus species with large, overlapping distributions grown
under contrasting ‘local’ temperature conditions (tropic and temperate)
to investigate the independent contribution of adaptation, plasticity,
and their interaction at molecular, physiological and morphological
levels. We find key traits differ in their response. The link between
gene expression and traits markedly differed between species. Divergent
evolution was the dominant pattern driving adaptation as unique gene
responses (91% of all significant genes) was the greatest factor
driving differentiation; but the few homologous responses were varied
depending on effect. For example, 98% of the plastic homologs were
similarly regulated, while 50% of the adaptive homologs and 100% of
the interaction homologs were antagonistically regulated. Suggesting
that parallel evolution between species among homologous genes for the
adaptive effect was no better than random. Further, heat shock proteins
for one species were almost entirely driven by adaptive responses, while
plasticity drove the response in the other species. These results
suggest divergent molecular evolutionary solutions dominated the
adaptive mechanisms among species, even in similar ecological
circumstances. Thus, trees with similar distributions are unlikely to
equally persist in the future, suggesting that management of future
forests to changing temperature conditions must be species specific.
Dissociation constants of eight amines: Experimental measurements and modeling
Authors: Liu Gao , Nguyen William , Henni Amr
Published: May 2022

In this study, the dissociation constants of the eight amines, namely,
N-(2-aminoethyl)-1,3-propanediamine, 2-methylpentamethylene diamine, N,
n-dimethyldipropylene-triamine, 3,3’-Diamino-n-methyldipropylamine,
Bis[2-(n, n-dimethylamino) ethyl]ether, 2-[2-(Dimethylamino)
ethoxy] Ethanol, 2-(dibutylamino) Ethanol and N-propylethanolamine
were determined from 298.15 K to 313.15 K. Using the van’t Hoff
equation, thermodynamic properties such as the standard state changes of
enthalpy, entropy and Gibbs free energy were calculated. Using
computational chemistry calculations, the amino group protonated first
was predicted. Furthermore, computer free group contribution methods
such as the original Perrin-Dempsey-Serjeant (PDS), the modified PDS and
the Qian-Sun-Sun-Gao (QSSG) model were used to estimate the dissociation
constants of the studied amines. In these methods, the QSSG provided the
most accurate results as the database used in this method was updated
with additional the functional groups as well as information about group
positions. Finally, an artificial neural network was used to predict the
pKa values.
Surgical site infection following orthopedic surgery in a patient with acne: A challenging case
Authors: Dadkhahfar Sahar , Ohadi Laya , Biglari Farsad , Kafiabadi Meisam Jafari
Published: May 2022

Propionibacterium acnes is a typical component of the human body’s flora
and has been implicated as the causative infectious agent following a
variety of medical operations. We present a case of a 21-year-old male
with severe global acneiform eruption with a non-healing limb lesion
near the orthopedic surgery incisions.
Nonlocal heat equations with generalized fractional Laplacian
Authors: Kossowski Igor , Przeradzki Bogdan
Published: May 2022

We study heat equtions with generalized fractional Laplacian, which is
defined by the spectral theory. Here, we develop the existence theory
for that equations. Moreover, we present some numerical simulations for
our problems.
A Rare Case of Mycotic Pulmonary Artery Aneurysm Complicated by Infective Endocarditis in Association with Ventricular Septal Defect
Authors: Vidiyala Pujitha , Shaw Manish , Kumar Sanjeev , Ramakrishnan Sivasubramanian
Published: May 2022

We present a case of a 3-year-old child with ventricular septal defect
and infective endocarditis with mycotic pulmonary artery aneurysm. The
case highlights the role of CT angiography in the diagnosis and
characterization of aneurysm and in demonstrating the extent of
thrombo-embolic complications in distal pulmonary arteries and lung
parenchyma.
The Control and Trust of CRISPR / Cas9 Genome Altering for Clinical Application with Gene Treatment and Treatment of Hereditary Diseases
Authors: Soltaninejad hossein , khoshandam mohadeseh , Hamidieh Amir Ali , Hosseinkhani Saman
Published: May 2022

Clustered Frequently Interspaced Brief Palindromic Rehashes (CRISPR) is
determined from the bacterial natural safe framework and designed as a
strong gene-editing apparatus. Due to the higher specificity and
proficiency of CRISPR/Cas9, it has been broadly connected to numerous
hereditary and non-genetic malady, counting cancers, hereditary
hemolytic illnesses, obtained immunodeficiency disorder, cardiovascular
illnesses, visual maladies, and neurodegenerative infections, and a few
X-linked maladies. Besides, in terms of the restorative technique of
cancers, numerous analysts have utilized the CRISPR/Cas9 procedure to
remedy or lighten cancers through diverse approaches, such as quality
treatment and resistant treatment. Here, we conclude the later
application and clinical trials of CRISPR/Cas9 in non-cancerous
illnesses and point out a few of the issues to be illuminated. Focus on
the toughest barrier to potential in vivo use of CRISPR / Cas9 is then
delivered. Shipping & Conveyance Vehicles Detailed to CRISPR / Cas9
Depict viral conveyance strategies (such as adenovirus-associated
infection (AAV), full-size, non-viral adenovirus, and lentivirus. Gold),
and we talk about their comparative focal points, which appear promising
in this respect.CRISPR/Cas9, determined from the microbial natural safe
framework, is created as a strong gene-editing device and has been
connected broadly. Due to its tall exactness and proficiency,
CRISPR/Cas9 strategies may give an awesome chance to treat a few
gene-related maladies by disturbing, embeddings, rectifying,
supplanting, or blocking qualities for clinical application with quality
therapy.
Organic substitution accumulates more nitrogen in soil while maintaining unchanged nitrogen use efficiency in rice-fava bean rotation system
Authors: Wang Panlei , Wang Bin , Chen Anqiang , Sun Xi , Du Caiyan , Zhu Hongye , Pan Yanhua , Tang Li
Published: May 2022

Organic substitution management (OSM) is critical for soil conservation
and nitrogen efficiency. However, assessment of soil N pool and system
NUE under paddy-upland rotation systems after OSM introduction is still
lacking, especially given the system’s alternating wetting-drying soil
environment and double cropping. Here, the response of soil nitrogen and
crop nitrogen use efficiency to OSM was evaluated in 2018, 2019 and
2020, basing on a long-term rice-fava bean rotation experiment started
in 2015. Soil nitrogen, soil enzymes and microbial functions were also
used to identify the key factors influencing nitrogen use in response to
OSM. The results showed that in comparison to chemical fertilization,
OSM increased the soil total nitrogen in both cropping seasons, with
increases of 13.1% for the rice season and 16.3% for the fava bean
season, respectively. However, nitrogen use efficiency (NUE) showed
season-specific responses to OSM. OSM decreased NUE by 18.2% in the
rice season but decreased by 8.0% in the fava bean season. Based on the
SEM analysis results, we suggest that the opposite response of NRE and
NUE to OSM across the studied seasons was mainly attributed to the
difference in crop nitrogen requirements and soil hydrological
conditions. In conclusion, in paddy-upland rotation areas where have
increasing demand for food and chemical fertilizers are currently
abused, the use of OSM has potential to curb regional soil degradation
due to its high capacity of improving soil quality while ensuring no
yield reduction.
Construction, expression and application of microbial β-1,3-glucanase for β-1,3-glucan oligosaccharide production
Authors: Xu Ying , Yang Guoshuai , Zhan Xiao-Bei , Hu Xiuyu , Gao Minjie
Published: May 2022

β-1,3-Glucan oligosaccharides produced by enzymatic hydrolysis of
β-1,3-glucans are of great interest, because they possess biological
functionalities such as regulating intestinal health, improving immunity
and anti-tumor. A significant qualification for the industrial
production of glucan oligosaccharides is β-1,3-glucanase with high
catalytic ability. These enzymes are widely present in fungi, bacteria,
plants and invertebrates, they are separated into glycoside hydrolase
families 3, 5, 16, 17, 55, 64, 72, 81, 128 and 132. This report presents
the research progress on the construction and expression of
β-1,3-glucanases in Pichia pastoris and Escherichia coli from different
microorganisms. Culture conditions and strategies to improve enzyme
activity in these hosts are summarized. The application of
β-1,3-glucanases in different β-1,3-glucans (curdlan, scleroglucan,
laminarin, and schizophyllan) degradation and their hydrolysate analysis
are reviewed. This review provides an important reference for further
modification and utilization of microbial β-1,3-glucanases in
large-scale production of multi-functional oligosaccharides.
Maternal Interleukin-17 and Disease Activity Influence Pregnancy Outcomes in Women with Psoriatic Arthritis and Ankylosing Spondylitis
Authors: Girbash Ehab , ABDELWAHAB SHAIMAA , ATEF REHAB , SHERIF HALA , ABDELDAYEM HUSSEIN , ATTA DOAA
Published: May 2022

Objective: We aimed in this study to evaluate the impact of maternal
interleukin -17A and the activity of the illness on pregnancy outcomes
in Psoriatic arthritis (PsA) and ankylosing spondylitis (AS) patients.
Methods: This prospective cohort research was carried out on 48
Psoriatic arthritis and ankylosing spondylitis pregnant women attending
the inpatient and outpatient clinics of Rheumatology & Rehabilitation
and Obstetrics & Gynecology Departments, Faculty of Medicine, Zagazig
university hospitals in Egypt and Yanbu National Hospital in KSA and 30
apparently healthy age- and sex-matched pregnant women between January
1,2018, and December 31, 2019. Results: The study group patients have
higher risk of preterm labour (32‐36 weeks’ gestation) (aRR 1.80, 95%
CI 0.79–4.17), oligohydramnios (aRR 3.15, 95% CI 1.26-8.42), Caesarean
delivery (aRR 1.57, 95% CI 1.41-2.68), and delivering infants small for
gestational age (aRR 7.04, 95% CI 2.36-12.42). There was significant
difference between the control group and the study groups regarding the
level IL-17A. Conclusion: A lot of females with PsA and AS have
uninhibited pregnancy as regards adverse events, but in comparison with
normal pregnancies particularly with high IL-17A during third trimester
we noticed a growing risk of preterm labour, oligohydramnios and
caesarean section.
Maternal and umbilical cord 25(OH)D levels at delivery and identification of factors affecting the correlation: a prospective observational study from a northern Emirate.
Authors: Jutell Magnus , Bagge Maria , Bhat Shakura , Isberg Per-Erik , Wiberg Nana
Published: May 2022

25-hydroxyvitamin-D (25(OH)D) level in the fetus entirely depends on the
transport over placenta which is assumed to be obstructed with maternal
levels <25nmol/L. Design Observational study. Setting
Prospectively enrolling from September to December 2021 in a tertiary
governmental hospital in a northern Emirate. Population Admission for
spontaneous and elective labor. Methods 25(OH)D was analyzed in maternal
serum at admission, respectively, in cord blood after delivery. Main
outcome measures Factors affecting maternal and fetal 25(OH)D levels and
the correlation between the two at delivery. Results 303 women were
enrolled and 237 had complete maternal/umbilical cord blood samples. 138
(47.7%) of women were diagnosed with deficiency
(25(OH)D<50nmol/L), whereas only 34 fetuses (13.8%) were
deficient (25(OH)D<30nmol/L). The mean difference between
maternal and cord blood 25(OH)D was negative in 91% of cases
(-16.27nmol/L, SD=13.36). The correlation between maternal/umbilical
cord levels was excellent (r = 0,906, p<0,000). After dividing
into subgroups of maternal 25(OH)D levels, BMI, diabetes yes/no and
delivery-mode the correlation was consistent, although the correlation
coefficients in the subgroups of maternal 25(OH)D levels were lowered
for all groups. Of factors studied, only the supplementation dose
affected the maternal 25(OH)D level. 25(OH)D <50nmol/L was not
associated to an increased risk for diabetes, preterm labor,
preterm-rupture-of-membranes or low Apgar-score. Conclusion We found a
higher 25(OH)D level in cord blood with consistent correlation to
maternal levels. Of the studied factors only supplementation dose had
significant impact on the maternal level. 25(OH)D <50nmol/l
were not associated to increased risk for preterm-labor,
preterm-rupture-of-membranes, diabetes or low AS.
Discontinuous Sturm-Liouville Problem with Eigenparameter-Dependent Boundary conditions and Herglotzs transmission
Authors: Du Gaofeng , Gao Chenghua , Wang Jingjing
Published: May 2022

This paper is to study a Sturm-Liouville equation
Ly:=-p(x)y’‘+q(x)y=\lambda y with discontinuities in the
case that eigenparameter appears not only in the differential equation
but also appears in both the boundary conditions
\lambda(\alpha’_{1}&y(-a)-\alpha’_{2}y’(-a))-(\alpha_{1}y(-a)-\alpha_{2}y’(-a))=0,
\lambda(\beta’_{1}y(b)-\beta’_{2}y’(b))+(\beta_{1}y(b)-\beta_{2}y’(b))=0
and transmission conditions as
-y(0^{+})&\bigg(\lambda\eta-\xi-\sum_{i=1}^{N}\frac{b_{i}^{2}}{\lambda-c_{i}}\bigg)=y’(0^{+})-y’(0^{-}),
y’(0^{-})&\bigg(\lambda\kappa+\zeta-\sum_{j=1}^{M}\frac{a_{j}^{2}}{\lambda-d_{j}}\bigg)=y(0^{+})-y(0^{-}).
In particular, in the space
L^{2}([-a,b])\oplus\mathbb{C}\oplus\mathbb{C}\oplus
\mathbb{C}^{N’}\oplus
\mathbb{C}^{M’}, the considered problem can be
interpreted as the eigenvalue problem of self-adjoint operator A.
Moreover, we construct the Green’s function of the considered problem
and resolvent operator of A.
Intrauterine Pregnancy with Copper Intrauterine Contraceptive Device in situ: A Case Report.
Authors: Rana Abilasha , Shrestha Amit , Aryal Shreyashi , Regmi Anil , Singh Rewant
Published: May 2022

Intrauterine pregnancy in the background of intrauterine devices heralds
its rare but possible failure. Despite having an excellent contraceptive
pearl index, clients with copper-T may present with typical pregnancy
symptoms. Term pregnancies with excellent prognosis have been
demonstrated in many studies after removal of intrauterine devices.
Central shunt for tetralogy of Fallot after original Blalock--Tasussig shunt in a 34-year-old woman
Authors: Nakanishi Keisuke , Kawasaki Shiori , Amano Atsushi , Tabata Minoru
Published: May 2022

A 34-year-old woman presented with original Blalock Taussig shunt and
tetralogy of Fallot. The anastomosis site of the original
Blalock–Taussig shunt revealed stenosis and severe cyanosis. A central
shunt was performed with 6mm artificial vessel, not a radical operation.
After surgery, the cyanosis improved as intended.
Optical control of insect behavior via ionotropic GABA receptors
Authors: ZHAO CHUN QING , Huang Qiu Tang , Shao Xu Sheng , Hou Qing Qing , Xu Qi , Zhou Cong , Du Yao Yao , Ji Yun Fan , Xu Zhi Ping , Cheng Jia Gao , Li Zhong
Published: May 2022

BACKGROUND AND PURPOSE Ionotropic GABA receptors (GABARs) in insects are
the major inhibitory receptor and common targets in insecticides for
pest control. Due to their high spatiotemporal resolution, the
photopharmacological ligands have been developed in vertebrates, but
only a few in insect yet. EXPERIMENTAL APPOACH In this study, two types
of photoswitchable ligands (PCLs) by incorporating photoswitch
azobenzene or dithienylethene into the antagonist, fipronil (FIP)
generated the DTFIPs (DTFIP1 and DTFIP2) and ABFIPs (p-, m-, and
o-ABFIP). Their photomodulation was measured by mosquito larval
behavior, and the potential action mechanism of them was explored by
two-electrode voltage clamp (TEVC) technique in vitro. KEY RESULTS
DTFIP1 and m-ABFIP exhibited biggest difference of insecticidal activity
between unirradiated and irradiated formation, and allowed for optical
control of insect locomotors activity in swimming. The TEVC assay
results indicted m-ABFIP and DTFIP1 enable optical control over the
homomeric RDL-type GABAR, which is achieved by regulating the chloride
channel of insect resistance to RDL-type GABAR by photoisomerization.
CONSLUSION AND IMPLICATIONS Our results suggested that PCLs provide an
alternative and precise tool for studying insect ionotropic GABARs and
GABA-dependent behavior.
Case Report: Successful Rechallenge With Cisplatin Following Cisplatin Induced Ischemic Cerebrovascular Accident In A Patient with Small Cell Lung Cancer.
Authors: Rahat Farah , Omar Nabil , Aakel Hassan , Al-Homsi Ussama , Shablak Alaaeldin
Published: May 2022

Cisplatin is a widely used platinum-based chemotherapy agent. Its common
adverse effects are neuropathy, nephrotoxicity, electrolyte abnormality,
and rarely causing thrombotic vascular toxicity. We present a patient
known to have Small-cell Lung Cancer who developed ischemic
cerebrovascular accident (CVA) after receiving chemotherapy regimen
including cisplatin.
An Improved Iterative Log Thresholding Algorithm for DFL in Subspace
Authors: Cheng Qin , Zhang Linghua , shu feng , wang xu , bo xue
Published: May 2022

In order to improve the efficiency and robustness of device-free
localization (DFL) systems in harsh environments, this letter proposed
an iterative log thresholding algorithm for DFL in subspace. The log
regularizer is taken as the constraint to optimize the object function.
To meet the requirement of real-time performance, the dimensions of
learning dictionary and observed vector are reduced with principal
component analysis (PCA), and the sparse coefficient vector is
iteratively computed with sparse coding algorithm. Eventually, by
projecting the reference points (RPs) index of the coefficient vectors
to the location of objects, the location is estimated. Numerical
experiment verified the effectiveness of the proposed algorithm over the
alternatives.
Participating in God's Purpose by Following the Cruciform Pattern of Christ: The Use of Psalm 69:9b in Romans 15:3
Authors: Wu Siu Fung
Published: May 2022

In his letter to the Romans, Paul emphasizes the importance of Israel's Scripture for his gospel (1:3–4; 16:25–27). In 15:4, he specifically links the Scriptures with endurance, consolation, and hope. Immediately before this verse, Paul cites Ps 69:9b. Commentators customarily—and rightly—think that Paul uses this citation to support his exhortation on community harmony in Rom 14–15. But is this the sole function of the citation? Does it, directly or indirectly, support other themes in Romans? Psalm 69 is significant for Romans, because it is cited in 11:9–10 and 15:3. It is also probable that Ps 69 played a significant role in the early church's understanding of Christ's suffering and death, because it is alluded to in the passion narratives in all four canonical gospels. But the use of Ps 69:9b in Rom 15:3 has drawn relatively little attention among scholars. This article suggests that the function of the citation is extensive, and it strengthens several main themes of the letter. More specifically, this article argues that the citation serves to reinforce Paul's call for believers to participate in God's purpose by following the cruciform pattern of Christ.
Galatians and the Progymnasmata on Refuting a Law: A Neglected Aspect of Pauline Rhetoric
Authors: Gordley Matthew E.
Published: May 2022

The structure, flow, and logic of Paul's argumentation in Galatians continues to be a subject of debate as scholars seek to read Paul's statements about the law, works of the law, and other aspects of Judaism within a framework that appreciates both the diverse nature of first-century Judaism and Paul's appropriation of his own Jewish heritage. Scholars have also sought to read Paul's letter to the Galatians in light of first-century Greco-Roman rhetorical strategies and conventions. This essay contributes to these discussions by looking at Galatians from an angle that has not yet been considered: the first-century A.D. progymnasmata exercise on the introduction and refutation of a law (νόμου εἰσφορά). This specific compositional exercise drew on the skills mastered in earlier exercises as students utilized compositional and rhetorical skills to persuade the reader (an imaginary audience) to enact or abandon a particular law based on the topics of legality, possibility, advantage, and appropriateness. By reading Galatians through the lens of this particular exercise, it is possible to appreciate the extent to which Paul utilized conventional forms of argumentation about the application of existing laws. This sort of reading contributes to a thicker description of Paul's use of elements of ancient rhetoric.
Recovering Paul's Hypothetical Slaves: Rhetoric and Reality in 1 Corinthians 7:21
Authors: Flexsenhar Michael
Published: May 2022

Current opinion on 1 Cor 7:21 is that Paul addresses slaves in his Corinthian churches concerning their social status as enslaved people, instructing them whether or not to take freedom if they have the opportunity. Most now conclude that Paul did not require these slaves to remain in their calling (slavery) but advised them to “make use of freedom.” This reading, however, does not fully appreciate Paul's rhetoric in its Greco-Roman context or its reception among the Corinthians. Nor does it capture the social realities of slavery and manumission as both Paul and the Corinthians understood them. Paul's comments about slavery take on a different light if we recognize that both Paul and the Corinthians presumed that slaves would indeed take freedom given the chance, because slaves did not have a choice. This social reality, I will suggest, helps account for the rhetorical nature and the sociocultural context of v. 21, and in turn sets it within Paul's broader concerns in 1 Cor 7. The textured reading I propose is that Paul's comments, though rooted in the reality of slavery, do not advise slaves concerning slavery or freedom. Slavery or freedom as such are not at issue in 1 Cor 7. Rather, Paul uses a diatribal and hence primarily hypothetical argument about slavery and manumission for other instructional purposes, and this reflects the conventions of Stoic moral instruction on indifference.