bluuebunny/crossref_metadata_2025 huggingface dataset:
Composition of Donkey Meat (Equus Asinus) from the Puno Region, Peru
Authors: Añasco Pedro Ubaldo Coila , Mamani Ruso Américo Ticona , Quispe Renán Dilton Hañari , Tapia Mery Luz Aliaga , Silva Walter Max Galindo , Carbajal Edwin Julio Condori , Mamani Hugo Vilcanqui
Published: October 2024

Objective: To determine the proximate chemical composition of donkey meat (Equus asinus) considering the variables of animal class (young and adult) and commercial cut (shoulder, rib and leg) with the purpose of nutritionally assessing it as an alternative source of red meat.
 
Theoretical Framework: Donkey meat is characterized by a low intramuscular fat content and could be used as a valid alternative to other species of red meat such as beef and sheep in the Puno region, Peru. However, little is known about the nutritional quality of meat from donkeys that are slaughtered at the main equine slaughterhouse in southern Peru.
 
Method: Muscle tissue samples were taken from the following muscles: deltoid, Longissimus dorsi and biceps femoris representing the commercial cuts of shoulder, rib and leg, respectively. Chemical analysis (moisture, protein, fat and ash) was performed following the protocols established for meat by the Association of Official Analytical Chemists (AOAC), in the Bromatology Laboratory of the Faculty of Veterinary Medicine and Zootechnics of UNA-Puno. Data analysis was performed in a randomized complete block design (DBCA) and the LSD significance test (α=0.05).
 
Results and Discussion: The proximate chemical composition of donkey meat is as follows: moisture 73.79%, protein 19.23%, fat 4.53% and ash 1.20%. The animal class (young and adult) and the commercial cut (shoulder, rib and leg) have a significant effect on the moisture and fat content (p≤0.05), with an inverse relationship between the two; but there is no effect on the protein and ash content (p>0.05).
 
Implications of the research: It was possible to demonstrate that the meat of donkeys from the Puno region has a similar composition to the red meat of other domestic species, so it can be a good alternative to replace red meat.
 
Originality/Value: This study contributes to the literature by knowing the chemical composition of donkey meat from the Puno region, Peru for consumption purposes as a substitute for red meat or for the preparation of meat by-products.
Análisis comparativo de separación de residuos entre académicos y estudiantes
Authors: Landa Reyes Claudia Anaid , Romero León Katia
Published: October 2024

La separación de los residuos sólidos urbanos desde la fuente representa una oportunidad para mejorar su tratamiento y aprovechamiento. En la Universidad Veracruzana, particularmente en la Unidad de Economía, Estadística e Informática (UEEI-UV) ubicada en la ciudad de Xalapa, Veracruz, se lleva a cabo un manejo ineficiente de los residuos sólidos urbanos generados. El objetivo es mostrar un análisis comparativo de los resultados de un diagnóstico exploratorio, realizado a través de una encuesta aplicada en 2023 a una muestra aleatoria de estudiantes y académicos cuya formación profesional no radica en generar o mantener un comportamiento proambiental. Se observan similitudes y diferencias en los conocimientos, percepciones y actitudes relacionadas al manejo de residuos de estos dos grupos poblacionales dentro de la Universidad. El resultado muestra características comparadas entre académicos y estudiantes en la disposición de residuos, mismas que fueron consideradas en la elaboración de un programa de gestión en la unidad.
 
Solid waste-sorting comparative analysis between professors and students: The case of Economics, Statistics and Informatics Unit at the Veracruzana University
Source sorting urban solid waste represents an opportunity to improve the treatment and use of discarded materials. At the Universidad Veracruzana, particularly in the Unidad de Economía, Estadística e Informática (UEEI-UV) located in the city of Xalapa, Veracruz, in the University’ space all solid waste is discarded indistinctly. This research applies a qualitative and comparative analysis of the data obtained from an exploratory diagnostic survey, applied to a random sample of students and academics whose professional education is not directly related to pro-environmental behavior. It shows the similarities and differences in knowledge, perceptions and attitudes related to waste management among students and professors.
Tratamientos psicológicos de pacientes psicóticos con cobertura del plan médico obligatorio
Authors: Barreira Ignacio , Comastri Silvia , Bevacqua Leandro Nicolás , Bidal María Camila , Varela Paula Daniela , Amaya César Gabriel , Vignati Pamela
Published: October 2024

El objetivo del presente estudio radica en evaluar la efectividad de tratamientos psicológicos realizados con pacientes con diagnóstico de psicosis con cobertura del Plan Médico Obligatorio (PMO). A tales fines, se realizó una evaluación longitudinal de personas que consultaron espontáneamente en un centro de salud mental radicado en la Ciudad Autónoma de Buenos Aires, que presentaron diagnóstico de trastorno del espectro de la esquizofrenia. La muestra relevada es de 15 consultantes que cumplieron con los criterios de inclusión. Los instrumentos utilizados fueron la escala PANSS y la COP 13, consignándose datos clínicos tales como motivos de consulta, focos acordados, objetivos cumplidos y logros. Los resultados que se presentan corresponden a evidencia generada entre abril de 2022 y noviembre de 2023. Se presentan resultados sobre motivos de consulta, focalización y logros de tratamiento, los mismos fueron trabajados con teoría fundamentada y luego se cuantificaron de modo tal que se estableció un análisis de frecuencias en relación con los constructos generados. Se plantea el debate sobre una adecuación parcial del PMO para estos pacientes.
Monitoreo de la campaña electoral por la presidencia de México 2024
Authors: Andrade Carmen Patricia , Pablo Contreras Mariangel
Published: October 2024

El Observatorio Veracruzano de Medios llevó a cabo el monitoreo de noticias emitidas en Portales Digitales: SDP Noticias, Milenio, Infobae, El Reforma, El Financiero, La Jornada, La Silla Rota, Sin Embargo, Uno TV y Aristegui Noticias, sobre la campaña electoral 2024. Los resultados del seguimiento muestran las estadísticas de cobertura de cada portal analizado - y otras variables - acerca de tres candidatas/o: Claudia Sheinbaum (MORENA), Xóchitl Gálvez (PRI/PAN/PRD) y Jorge Máynez (Movimiento Ciudadano).  El estudio resulta en una mayor cobertura para la Candidata Claudia Sheinbaum (MORENA).
 
Monitoring of the electoral campaign for the presidency of Mexico 2024
Abstract: The Observatorio Veracruzano de Medios carried out monitoring of news broadcast on Digital Portals: SDP Noticias, Milenio, Infobae, El Reforma, El Financiero, La Jornada, La Silla Rota, Sin Embargo, Uno TV and Aristegui Noticias, about the electoral campaign 2024. The monitoring results show the coverage statistics of each portal analyzed - and other variables - about three candidates: Claudia Sheinbaum (MORENA), Xóchitl Gálvez (PRI/PAN/PRD) and Jorge Máynez (Movimiento Ciudadano). The study results in greater coverage for Candidate Claudia Sheinbaum (MORENA).
Keywords: Mexico; Elections 2024; Monitoring; Digital portals; Content analysis.
Exploring the dimensions of contemporary museum management
Authors:   National University of Political Studies and Public Administration, BĂLAN Emanuela Ana-Maria
Published: October 2024

Museums have acquired new roles, thus becoming active actors in society against the backdrop of the expectations of cultural consumers. In addition, consumers now have a higher demand for Romanian museums after visiting great European museums. The managerial approach continues to change considerably, reaching the point where it focuses more on aspects such as activism, sustainability, diversity, inclusion, and interactivity to encourage and bring together people from diverse socio-cultural backgrounds around a museum. Speaking about interactivity, one of the ways of attracting a diverse public is the adoption of new technologies such as VR and AI. The paper outlines some of the main dimensions and sub-dimensions associated with the management of a modern museum. It discusses how managerial best practices align with the new ICOM definition of a museum, using the latter as a benchmark. More specifically, modern museum management means participation, sustainability, activism, and new technologies. The investigation suggests that the definition adopted by ICOM is, to some extent, outdated compared to practice and cannot be relied upon alone to define the management of a modern museum.
Knowledge translation
Authors:   National University of Political Studies and Public Administration, BRATIANU Constantin
Published: October 2024

This paper aims to present some conceptual models for the knowledge translation process in its extended semantic dimension. Knowledge translation is usually understood through its primary meaning of translating from one language into another language. However, knowledge translation is a concept with a larger semantic universe used in recent years in many research domains, especially in healthcare systems. The basic idea is to maximize the knowledge transfer between a sender and a receiver, understanding the receiver's knowledge deficit and absorptive capacity. The method used in this paper is a functional analysis of different types of knowledge transfer and of searching for their critical elements. Based on this functional analysis, the paper presents a series of knowledge translation models and some basic competencies for people who initiate knowledge translation. Findings show the complexity of the expert knowledge translation and the need to transform the direct linear process into a series of several processes linked in a cascade. For each sequence, there is a smaller knowledge deficit than the initial one, such that the absorptive capacity of the receiver can accept it.
Analysis of the Romanian pension system in the context of the national recovery and resilience plan
Authors:   Romanian-American University, CROITORU Elena-Lucia , ROȘU Alexandru-Cristian ,   Romanian-American University
Published: October 2024

A new pension law, which aims to increase the small ones and allows the sustainability of the pension system, equity, and compliance with the principle of contribution, must be the desire of the Romanian Government to eliminate the inequities produced by the laws in force in the field of pensions and social insurance. Since there are delays in the calendar agreed with the European Commission in complying with the milestones of the National Recovery and Resilience Program, Romania will no longer receive a single euro from the 5.5 billion euros allocated to 2023, so at least for this year, no amount will no longer be available. According to the European Commission, when the pension system is not substantially reformed, the collapse will be inevitable. In the long term, the only possibility of paying pension rights will be realized only through the devaluation of the national currency or through loans from external sources. According to the Recommendation of the Council regarding the National Reform Program of Romania for 2023, which includes an opinion of the Council regarding the Convergence Program of Romania for 2023, the cost of not reforming the system for Romania’s GDP is about 3%.
Green banking practices. Essential tools for attaining the sustainable development objectives of the European taxonomy
Authors:   National University of Political Studies and Public Administration, GHEORGHIU Anda
Published: October 2024

Although banks do not significantly impact the natural environment, they have an indirect intermediary role in promoting sustainability issues by financing environmentalfriendly businesses. The paper aims to briefly clarify notions such as green banking, ESG, and European Taxonomy and analyze the progress made by Romanian banks in implementing them. For the time being, the scientific literature lacks a systematic analysis of green banking correlated to the sustainable development objectives of the European Taxonomy. The research hypotheses of the paper are a comparison of green banking practices of the top ten Romanian banks and the degree to which banks in Romania have achieved the six main environmental objectives established by article no. 9 of Regulation (EU) 2020/852, namely: mitigation of climate change, adaptation to it, sustainable use of waters, protection of water and marine resources, transition to a circular economy, prevention and control of pollution and protection and restoration of biodiversity and ecosystems. For both hypotheses, most data were collected by the author from the annual reports published by the banks, referring to the year 2022, and then classified and analyzed to reach a conclusion. The study reveals that most Romanian banks have implemented or are in the process of implementing the objectives of the European Taxonomy and the 2030 Agenda. Regrettably, very little was done in the domains of sustainable use and protection of water and marine resources or the protection and restoration of biodiversity and ecosystems, so, in future years, banks should try to focus more on these objectives. Banks should also concentrate their efforts on financing sustainable projects, responsible lending that avoids funding projects that damage the environment or violate social standards, and minimizing the environmental footprint of banks by implementing energy-efficient practices.
Sustainability and risks of introducing AI
Authors:   Transylvania University of Brasov, GOGA Alexandru-Silviu , BOȘCOIANU Mircea ,   Transylvania University of Brasov
Published: October 2024

The paper highlights that innovation and sustainability are paramount challenges in the modern world, requiring new approaches considering environmental concerns. Artificial Intelligence is identified as a valuable tool to address these challenges by accelerating innovation in various domains, including renewable energy, energy efficiency, waste reduction, and environmental monitoring. The paper provides specific examples of AI applications in these areas. The risks of AI implementation in industrial management are examined, including concerns related to bias, transparency, safety, job displacement, loss of control, malicious use, and societal disruption. Mitigation strategies for these risks are outlined, emphasizing careful planning, human oversight, data quality, ethical guidelines, and industry collaboration. Case studies illustrate real-world incidents and concerns related to AI in industrial settings, including Tesla's Autopilot system, Amazon's hiring algorithm, Clearview AI's facial recognition technology, and Toyota's recent production disruption. In conclusion, the paper uses multiple research methods to emphasize the need for a balanced approach to AI adoption. It recognizes its potential benefits and the importance of addressing associated risks to ensure responsible and safe usage in industrial management.
Impact of demographic change on society: active ageing, silver economy and strategic business
Authors:   University of Insubria, QUERCI Elena , GAZZOLA Patrizia ,   University of Insubria
Published: October 2024

The changes in the structure of the population worldwide, particularly in Europe and the United States, have determined the transition of the population with a demographic dividend characterized by the increase in the life span of the elderly population and the fertility capacities with the result of low birth rate and low mortality. The expected negative effects on the economic growth of the current demographic change can be mitigated by prolonging the participation of seniors in the workforce, managing migration correctly, improving financial flows, and using the IoT to increase productivity. In reality, there is a scenario with even positive implications since an aging population opens up a market that has not been fully explored and exploited. A longevity society is a multidimensional target for the Silver Economy. The spending power of the baby boomers is high. It is aimed at sectors such as training, health care, housing, information and communication technologies, travel and tourism, and cultural and leisure activities. In the 2021 Green Paper, the European Commission outlines the guidelines for active and healthy aging through the promotion of healthy lifestyles throughout life, positively impacting the labor market, employment rates, social protection systems, and, therefore, economic growth and productivity. The UN 2030 goals examine longevity and its impact on society by suggesting actions to promote healthy aging to address inequalities and ensure older people age safely in a place that suits them, are free from poverty, continuing to develop their skills by contributing to their community, maintaining autonomy and health.
Modeling Kinetics and Transport Mechanism Study of Poorly Soluble Drug Formulation in High Acidic Medium
Authors: Al-Ali Maha , Al-Ali Laith I.
Published: October 2024

Some medicinal particles are poorly soluble in highly acidic solutions, particularly those subjected to various production processes. Therefore, the present research investigated the kinetics and mechanisms of the drug release rate of newly formulated solid pills in a low pH medium. Three pills were prepared: one from a non-moisturized powder mixture (PILD) and the other two, PILC and PILM, from the dried powder mixtures, which were dried using hot-air heating and microwave radiation, respectively. These pills were subjected to drug release tests, and the outcomes were considered in the kinetics investigation using various models. Zero-order, Hixson–Crowell, First-order, Higuchi, Hopfenberg, Korsmeyer-Peppas, Logistic, and Peppas-Sahlin were the kinetic models used to inspect the release rate mechanism of these tablets. It was found that the Peppas-Sahlin and zero-order were the most reliable models to represent the drug release profile of all prepared pills with very high accuracy, estimated by R^2>0.99. The Hixon and first-order models were the weakest to characterize this work outcome. This work also applied these models to describe the controlling mechanism of the drug release for each prepared pill. It is detected that the non-Fickian diffusion and polymer chain relaxation control the PILC’s release behavior. However, case II transport and super case II transport with erosions is the dominant mechanism for PILD and PILM pills, respectively. Additionally, new semi-empirical models were modified to describe the kinetics of the solid release of those tablets with greater accuracy.
Musculoskeletal Tissue Asymmetries Following Anterior Cruciate Ligament Reconstruction
Authors: Anderson Olivia K. , Redinger Allen L. , Mintz Emery L. , Voskuil Caleb C. , Mogonye Jason A. , Baker Breanne S. , Carr Joshua C.
Published: October 2024

OBJECTIVE: To compare musculoskeletal tissue asymmetries between those who had undergone anterior cruciate ligament reconstruction (ACLR) and nonsurgical controls, and to evaluate the influence of sex on asymmetries and perceptions of knee function in ACLR patients.

DESIGN: Cross-sectional cohort analysis.

METHODS: Individuals (female, n = 11; male, n = 11) with a history of ACLR and matched controls (female, n = 10; male, n = 9) completed dual-energy x-ray absorptiometry scans to measure lower-body bone mineral content (BMC), total body fat percent (Fat%), and lean mass (LM). Perceptions of knee function were captured via the International Knee Documentation Committee (IKDC) instrument and interlimb asymmetry indices (AI%) were calculated for each dual-energy x-ray absorptiometry outcome. Surgical groups and sexes were compared using independent t tests ( P<.05) and Cohen’s effect sizes ( d). Additionally, Pearson’s correlation coefficients evaluated the association between AI% and IKDC scores.

RESULTS: The ACLR group showed greater lower-body asymmetries, specifically less BMC and LM and greater Fat% in the ACLR limb ( P≤.044, d = 0.63-0.87). ACLR group sex comparisons found that females had lower IKDC scores, greater asymmetries for BMC and LM ( P≤.027, d = 0.40-0.74), and these asymmetries were negatively correlated with IKDC scores (all r≥0.755, P≤.007) while males demonstrated no such correlations.

CONCLUSIONS: Individuals with a history of ACLR had persistent musculoskeletal tissue asymmetries that favored the nonsurgical leg. The asymmetries were greater in female versus male patients and were associated with lower perceptions of knee function. Thus, musculoskeletal imaging may provide complementary information to the current standard of care during ACLR rehabilitation. JOSPT Open 2025;3(1):59-68. Epub 28 October 2024. doi:10.2519/josptopen.2024.1242
Procedimento de Whipple: Objetivos, indicações e prognóstico
Authors: Silva Cainan Vítor Santos Pinto da , Guimarães Carlos Eduardo Silva , Carvalho Esther Grzesiuk de , Costa Gabriella Fernanda Moraes , Martire João Pedro Lopes , Barba Leonardo Ribeiro Della , Silva Nathalia Adorno , Zorman Vinícius Santiago , Ridolfi Michelli Daltro Coelho
Published: October 2024

Objetivo: Abordar o procedimento de Whipple, elucidando as indicações, técnicas e prognóstico. Revisão bibliográfica: A duodenopancreatectomia, também conhecida como procedimento de Whipple, é um procedimento de alta complexidade técnica, comumente utilizado para o tratamento de tumores pancreáticos e periampulares. Consistia originalmente na remoção da cabeça do pâncreas, do duodeno, dos primeiros 15cm do jejuno, do ducto biliar comum e uma gastrectomia parcial. Contudo, avanços na precisão diagnóstica permitem que o procedimento seja readequado às necessidades do paciente. Associado a isso, o aprimoramento técnico e o surgimento de métodos cirúrgicos por vídeo e robóticos, promoveram a redução da mortalidade original de 40% para menos de 5%. A indicação para o procedimento é feita principalmente para casos de neoplasia de pâncreas, neoplasia de vias biliares, neoplasias duodenais e a pancreatite crônica grave. Considerações finais: O prognóstico está associado à localização da neoplasia, assim como o tempo de evolução até o diagnóstico. Ademais, a qualidade de sobrevida do paciente é associada à qualificação técnica da equipe cirúrgica e multidisciplinar, apresentando significativa divergência quando realizado em centros de referência.
Perfil epidemiológico dos casos de AIDS no Rio Grande do Norte entre 2019 a 2023
Authors: Borges Cícero Romero Miguel da Costa , Santos Lorena Ellen Souza dos
Published: October 2024

Objetivo: Identificar o perfil epidemiológico dos casos de Aids no estado do Rio Grande do Norte nos últimos cinco anos. Métodos: Trata-se de um estudo epidemiológico, descritivo, com abordagem quantitativa, com todos os casos diagnosticados com Aids no estado do Rio Grande do Norte, ocorridos entre os meses de janeiro de 2019 a 2023 e registrados na aba Informações em Saúde, presente no Departamento de Informática do Sistema Único de Saúde. Resultados: Durante o período de 2019 a 2023, foram notificados 157.308 casos no Brasil. Desses, foram identificados 1.496 casos de Aids no estado do Rio Grande do Norte, representando 0,95% a nível nacional. Dos quais, 365 foram no ano de 2019; 275 em 2020; 356 em 2021; 357 em 2022 e 143 casos em 2023. Essa amostra foram analisadas dentro das variáveis previamente definidas de faixa etária, sexo, escolaridade e categoria de exposição hierárquica . Conclusão: Os resultados evidenciaram que o perfil dos casos de Aids no Rio Grande do Norte durante o período de 2019 a 2023 foram, principalmente, indivíduos do sexo masculino, jovens, heterossexuais, com menor nível educacional e que apresentassem comportamentos de risco.
Índice vacinal de doses aplicadas contra a COVID-19 no Rio Grande do Norte
Authors: Borges Cícero Romero Miguel da Costa , Santos Lorena Ellen Souza dos
Published: October 2024

Objetivo: Evidenciar o índice vacinal de doses aplicadas contra a COVID-19 no estado do Rio Grande do Norte. Métodos: Trata-se de um estudo do tipo epidemiológico, retrospectivo com abordagem quantitativa. Os dados firam coletados por meio da análise de registros contidos no Vacinômetro COVID-19 a respeito da vacinação contra a Covid-19 ocorrida no estado do Rio Grande do Norte, através dos dados fornecidos pelo próprio sistema, com as variáveis previamente selecionadas. Resultados: Os dados presentes na ferramenta do Ministério da Saúde evidenciam que, no estado do Rio Grande do Norte, foram aplicadas 8.798.838 doses de vacinas monovalentes e foram aplicadas 527.509 doses contra o vírus SARS-CoV-2 e a variante Omicron – vacinas bivalentes. Verificou-se que 1.490.036 doses foram aplicadas na população indígena e especificamente na população quilombola, observou-se uma totalidade de 26.407 doses. Conclusão: Percebeu-se prevalência de um perfil: mulheres, com meia-idade. Além de uma tendência de redução do quantitativo a cada nova dose, ou seja, as pessoas tomavam a primeira e segunda e sentiam-se seguros.
Análise da cobertura vacinal da tríplice viral no Brasil
Authors: Couto Ana Beatriz Rosendo , Silva Eduarda Nayane Santos da , Barros Nyelle Nunes , Silva Deysiane Morgana da , Silva Paloma Barbosa da Costa , Silva Felipe Paulo da , Assis Tibério César Teixeira de , Melo Ingrid Maria de Almeida , Silva Anna Luiza , Lima Ellison Neves de
Published: October 2024

Objetivo: Analisar a cobertura vacinal da Tríplice Viral nas regiões do Brasil de 2000 a 2022. Métodos: Trata-se de uma pesquisa documental retrospectiva, realizada pela base de dados TABNET, com a intenção de analisar os dados da cobertura vacinal da Tríplice Viral no Brasil de 2000 a 2022. Resultados: Em geral, a cobertura vacinal do Brasil apresenta homogeneidade entre as regiões, com quedas e crescimentos sempre semelhantes. No ano de 2003 todas as regiões apresentavam CV da D1 acima dos 95% e esse feito perdura até 2014. Em 2017 nenhuma região conseguiu alcançar o esperado, perdurando assim até o fim do estudo (2022). Relacionado a CV da D2, os dados só são expressos a partir de 2013 no TABNET e 2014 foi o único ano a atingir o previsto e apenas para a região Nordeste com 95,21% e a região Centro-Oeste com 99,27%. Conclusão: Constata-se que a CV da D1 alcançou ótimos números, contudo desde 2015 essa cobertura vem caindo drasticamente. A CV da D2 quase nunca foi satisfatória e por falta de dados, só é possível analisar a partir de 2013, o que gera uma lacuna.
Mudança comportamental na doença renal crônica por meio da abordagem motivacional conduzida pelo enfermeiro: relato de experiência
Authors: Biancamano Aline de Oliveira , Camacho Alessandra Conceição Leite Funchal , Cortez Elaine Antunes , Almeida Yasmin Saba de
Published: October 2024

Objetivo: Descrever como a abordagem motivacional conduzida por enfermeiros possibilita a mudança de comportamento para melhoria da adesão ao tratamento, redução da progressão da doença renal e diminuição da angústia e do sofrimento acerca do enfrentamento da doença. Relato de experiência: Trata-se de um relato de experiência acerca da atuação de um enfermeiro do serviço de nefrologia de um hospital de referência na especialidade, sobretudo para pacientes com doença renal crônica que residam fora do município do Rio de Janeiro. A experiência ocorreu entre março e maio de 2024. Os resultados demonstram que com a progressão da doença renal crônica, a motivação dos pacientes diminui, levando à falta de adesão e afastamento de suas relações com profissionais de saúde. Desta forma, em sua assistência, o enfermeiro deve evocar as motivações dos pacientes para mudanças, buscando o melhor caminho para alcançar seus objetivos. Considerações finais: A experiência demonstra a importância da abordagem motivacional, guiando a conduta dos enfermeiros na mudança de comportamento dos pacientes com doença renal crônica. Isso permite que os pacientes reconheçam suas falhas, fortaleçam a adesão ao tratamento e atenuem a angústia relacionada ao enfrentamento da doença.
Worte ohne Lieder. Sprachästhetik und musikalisches Schreiben bei Adorno
Authors: Urbanek Nikolaus
Published: October 2024

"Es gibt kein richtiges Leben im falschen." – "Philosophie ist das Allerernsteste, aber so ernst wieder auch nicht." – "Aufgabe von Kunst heute ist es, Chaos in die Ordnung zu bringen." Solche pointierten Formulierungen haben Theodor W. Adorno in weiten Kreisen bekannt gemacht, und oft werden sie in falscher Vereindeutigung für die komplexe gedankliche Bewegung seiner Texte substituiert. Nichtsdestoweniger leben Adornos Texte von der Spannung, die von seiner mitunter hermetischen, oft aber unvermutet anschaulichen und von polemischem Witz immer wieder durchbrochenen Sprache ausgeht. Das wird auch und gerade in jenem Bereich seines Schreibens deutlich, der auf alle anderen ausgestrahlt hat, und dem Adorno die prägnant doppelsinnige Bezeichnung "Musikalische Schriften" gab; ähnlich, wie er in späteren Jahren von "Ästhetischer Theorie" sprach. Dieser Band widmet sich aus interdisziplinärer Perspektive Aspekten der Sprache, des Stils und des Schreibens, insbesondere aber dem Verhältnis von sprachlich artikuliertem Gedanken und musikalischem Denken bei Adorno. Mit Beiträgen von Max Beck und Nicholas Coomann, Lars Fischer, Julia Freund, Wolfgang Fuhrmann, Gabriele Geml, Pola Groß, Christian Grüny, Hans-Joachim Hinrichsen, Han-Gyeol Lie, Cosima Linke, Karsten Mackensen, Claus-Steffen Mahnkopf, Michael Schwarz, Elettra Villani, Boris Voigt und Sophie Zehetmayer.
An empirical study of pistachio production and its forecast in Afghanistan
Authors: S.M. Mowahed , Zada M.W. Sharif
Published: October 2024

This article discusses the statistical analysis of pistachio production in the last 46 years and its forecast for the next 10 years in Afghanistan. The premier focus of this paper is to find the effect of pistachio production in the next years by using the data of the previous years from 1976-2022, and by analyzing time-series data using the ARIMA model. For better and more precise results we used Eviews 10 for data analysis for the ARIMA model. The coefficients of the obtained model are statistically significant and show that the previous period of pistachio production and its errors can significantly affect the future period of pistachio production. Even though the forecast shows that pistachio production has not increased significantly between 2023 and 2032, the corresponding line shows decreasing pistachio production in coming years. Therefore, according to this estimation, Afghanistan will experience a significant decrease in pistachio production in the coming ten years.

В этой статье обсуждается статистический анализ производства фисташек за последние 46 лет и его прогноз на следующие 10 лет в Афганистане. Основное внимание в этой статье уделяется поиску эффекта производства фисташек в последующие годы с использованием данных за предыдущие годы с 1976 по 2022 год и путем анализа данных временных рядов с использованием модели ARIMA. Для получения лучших и более точных результатов мы использовали Eviews 10 для анализа данных для модели ARIMA. Коэффициенты полученной модели статистически значимы и показывают, что предыдущий период производства фисташек и его ошибки могут существенно повлиять на будущий период производства фисташек. Несмотря на то, что прогноз показывает, что производство фисташек существенно не увеличится между 2023 и 2032 годами, соответствующая линия показывает снижение производства фисташек в ближайшие годы. Таким образом, согласно этой оценке, в Афганистане в ближайшие десять лет произойдет значительное снижение производства фисташек.
Determinants of Venture Investment Size in Indian Unicorn Companies
Authors: A.V. Novikov
Published: October 2024

The objective of this comprehensive study is to elucidate the critical factors that determine the magnitude of venture investment in Indian unicorn companies during subsequent rounds, beginning with the second. With a keen focus on a sample of 37 unicorn firms during the year 2022, the study scrutinizes a plethora of influential elements that may enhance the size of investments within the Indian economic landscape. This research is built upon an exhaustive analysis of the multifaceted elements such as industry, investor experience, initial investment quantum, and a host of other germane factors, that all work in synergy to shape the unique attributes of the Indian startup ecosystem. Moreover, the investment environment of this emerging market is evaluated and compared with global standards to understand the defining characteristics that contribute to its individuality. The study thus serves as an extensive guide for venture capital investors, stakeholders in the Indian startup ecosystem, policy-makers, and researchers by shedding light on any distinctive features of the Indian market that may have contributed to the observed results, and outlining potential future avenues for further investigation.

Целью данного комплексного исследования является выявление ключевых факторов, определяющих величину венчурных инвестиций в индийские компании-«единороги» на последующих раундах, начиная со второго. Особое внимание уделяется выборке из 37 компаний-«единорогов» в 2022 году, исследуются многочисленные факторы, способствующие увеличению объема инвестиций в условиях индийской экономики. Это исследование основывается на всестороннем анализе множества элементов, таких как отрасль, опыт инвесторов, начальный объем инвестиций и другие важные факторы, которые совместно формируют уникальные особенности индийской экосистемы стартапов. Кроме того, инвестиционный климат этого развивающегося рынка оценивается и сравнивается с мировыми стандартами для понимания отличительных черт, которые способствуют его индивидуальности. Таким образом, исследование служит всеобъемлющим руководством для венчурных инвесторов, участников индийской экосистемы стартапов, политиков и исследователей, освещая характерные особенности индийского рынка, которые могли повлиять на наблюдаемые результаты, а также указывая на возможные направления для дальнейшего изучения.
Влияние санкций на международную торговлю Российской Федерации
Authors: А.Т. Шадыев
Published: October 2024

Настоящая статья посвящена исследованию последствий санкционного давления на внешнеэкономическую деятельность Российской Федерации с момента их введения в 2014 году. Рассматриваются изменения в торговом обороте, трансформация структуры внешнеторговых связей, а также адаптация бизнеса в ответ на ограничительные меры. В статье проводится анализ изменений в экспорте и импорте, особенно в секторах энергетики, машиностроения и сельского хозяйства. На основе выявленных тенденций предложены меры по повышению устойчивости внешнеэкономической деятельности в условиях санкций.

This article is devoted to studying the consequences of sanctions pressure on the foreign economic activity of the Russian Federation since their introduction in 2014. It examines changes in trade turnover, transformation of the structure of foreign trade relations, as well as business adaptation in response to restrictive measures. The article analyzes changes in exports and imports, especially in the sectors of energy, engineering and agriculture. Based on the identified trends, measures are proposed to increase the sustainability of foreign economic activity under sanctions.
ОСНОВНЫЕ РЕЗУЛЬТАТЫ АНАЛИЗА ПРИМЕНИМОСТИ СТАНДАРТОВ МАГАТЭ К ПРОЕКТУ РЕАКТОРНОЙ УСТАНОВКИ РИТМ-200Н ДЛЯ АТОМНЫХ СТАНЦИЙ МАЛОЙ МОЩНОСТИ
Authors: В.В. Петрунин , А.М. Бахметьев , А.В. Кураченков , В.Ю. Галицких , Ю.А. Макеев , Д.В. Щекин
Published: October 2024

Нормы безопасности Международного агентства по атомной энергии (МАГАТЭ) содержат принципы, требования и рекомендации по обеспечению безопасности и являются согласованным и общепринятым ориентиром эффективного выполнения международных обязательств стран, использующих атомную энергию в мирных целях. Действующие нормы Агентства применимы, как правило, к наземным стационарным атомным электростанциям с водоохлаждаемыми реакторами мощностью от 600 до 1 500 МВт. Для других типов реакторов, включая инновационные разработки, в том числе атомные станции малой мощности, некоторые положения по безопасности могут оказаться неприменимыми или же применимыми с определенными изменениями. В статье представлены основные результаты анализа применимости стандартов МАГАТЭ к проекту реакторной установки РИТМ-200Н для наземных атомных станций малой мощности.

The International Atomic Energy Agency (IAEA) safety standards contain safety principles, requirements and recommendations and are a consistent and generally accepted guideline for the effective fulfilment of international obligations of countries that use nuclear energy for peaceful purposes. The current Agency standards are generally applicable to land-based stationary nuclear power plants with water-cooled reactors with a capacity ranging from 600 to 1 500 mW. For other types of reactors, including innovative designs such as small nuclear power plants, some safety provisions may not be applicable or may be applicable with certain modifications. The paper provides the main results of the analysis of the applicability of the IAEA standards to the design of the RITM-200N reactor plant for land-based small nuclear power plants.
التوافق الاجتماعي وعلاقته بالثقة بالنفس (دراسة تطبيقية على عينة من طلاب جامعة الملك عبد العزيز في محافظة جدة)
Authors: المعبدي محمد أحمد
Published: October 2024

هدفت الدراسة الراهنة إلى التعرف على التوافق الاجتماعي وعلاقته بالثقة بالنفس ودور الجامعة في تعزيزها لدى طلاب الجامعة، وذلك من خلال استخدام المسح الاجتماعي كمنهج للدراسة لجمع البيانات عن طريق أداة الاستبانة من عينة عشوائية من طلاب بعض أقسام كلية الآداب والعلوم الإنسانية بجامعة الملك عبد العزيز بجدة بلغت (401) مفردة. وقد توصلت الدراسة لنتائج من أهمها: أن توفر التوافق الاجتماعي لدى عينة الدراسة كان بدرجة كبيرة، وكان أكثر العوامل التي تبين هذا الواقع هو المقدرة على التوافق مع البيئة الجامعية، بينما ظهر أن أقل هذه العوامل يتمثل في تخوف أفراد العينة من مجابهة المواقف الاجتماعية أياً كان نوعها؛ وأتضح أن عدم وجود أنانية لدى الطالب الجامعي وحب النفس أكثر من الغير يعد أكثر العوامل التي تسهم في تعزيز الثقة بالنفس لدى أفراد العينة، بينما يتمثل أقل العوامل في أن التحصيل الأكاديمي يشجع طلاب الجامعة على المزيد من التعلم، كما اتضح أن لدور للجامعة دوراً حول مدى توفر هذه العوامل والذي جاء بدرجة كبيرة، ف حين أن هناك فروق ذات دلالة احصائية لمتغيرات المستوى الدراسي، والمشاركة في الأنشطة اللاصفية، ومستوى تعليم الأبفي محور "الجوانب التي تكسب الطالب ثقته بنفسه"، وكذلك توجد فروق ذات دلالة احصائية بين المعدل التراكمي، ومستوى تعليم الأم، ومستوى دخل الأسرة في دور الجامعة في التوافق الاجتماعي.
دور المحميات الطبيعية في السياحة البيئية المستدامة محمية الإمام سعود بن عبد العزيز (محازة الصيد)
Authors: الكحيلي سماح رباح
Published: October 2024

أوضحت الدراسة ان المحميات الطبيعية تلعب دوراً حيوياً في تعزيز السياحة البيئية والتنمية المستدامة . مما يسهم في جذب السياح وتنمية الادراك لديهم وتوعيتهم للنواحي البيئية الهامة والتي تستدعي الحفاظ عليها مما يعزز لسياحة مستدامة في المنطقة . فالمحميات الطبيعية لها طابع جمالي خاص بها مثل محمية محازة الصيد الواقعة في المنطقة الغربية من المملكة العربية السعودية، على بعد 180 كيلومتر شمال شرق مدينة الطائف وهي تابعة لمنطقة مكة المكرمة.  وأسهمت المحمية بشكل كبير في الحفاظ على العديد من الجوانب الحيوية. والقت الدراسة الضوء على المحميات الطبيعية في منطقة مكة المكرمة ومالها من دور فعال في جانب السياحة البيئية والتنمية المستدامة والتي تعود بالنفع على مختلف الجوانب البيئية والاجتماعية والاقتصادية للمنطقة .  وهدفت الدراسة التعرف على دور المحميات الطبيعة في السياحة البيئية المستدامة . واتبعت الدراسة المنهج الوصفي التحليلي من خلال التعريف بمنطقة الدراسة بالاعتماد على الدراسات النظرية . والتحليل من خلال المرئيات الفضائية من القمر الصناعي  LANDSAT8. وتوصلت الدراسة الى ان المحمية تعد من المناطق البكر والتي لا يوجد فيها سياحة بيئية قائمة في المنطقةى، بل أن هناك خطط لإقامة هذا النوع من السياحة في المستقبل من خلال الورش المقامة للعاملين في الموقع. واوصت الدراسة بعدم قيام سياحة بيئية في المنطقة نظرا لأنها منطقة طبيعية ولم تتواجد بها الحيوانات الا لكون المحمية بعيدة عن النشاط البشري. وقد يتناسب مع هذا النوع من البيئات الحساسة السياحة البيئية التي تعتمد على المشي والاستمتاع والتواصل مع الطبيعة والتعرف على الطيور والحيوانات في المحمية.
Data-driven Workflow for the Development and Discovery of N-oxyl Hydrogen Atom Transfer Catalysts
Authors: Yang Cheng , Wild Thérèse , Rakova Yulia , Maldonado Stephen , Sigman Matthew , Stephenson Corey
Published: October 2024

N-oxyl species are promising hydrogen atom transfer (HAT) catalysts to advance C–H bond activation reactions. However, because of the complex structure-activity relationship within the N-oxyl structure, catalyst optimization is a key challenge, particularly for simultaneous improvement across multiple parameters. This paper describes a data-driven approach to op-timize N-oxyl hydrogen atom transfer catalysts. A focused library of 50 N-hydroxy compounds was synthesized and char-acterized by three parameters – oxidation peak potential, HAT reactivity, and stability – to generate a database. Statistical modeling of these activities described by their intrinsic physical organic parameters was used to build predictive models for catalyst discovery and to understand their structure-activity relationships. Virtual screening of 102 synthesizable candidates allowed for rapid identification of several ideal catalyst candidates. These statistical models clearly suggest that N-oxyl sub-structures bearing an adjacent heteroatom as more optimal HAT catalysts compared to the historical focus, phthalimide-N-oxyl, by striking the best balance among all three target experimental properties.
Reexamining the Enhanced Solubility of Sodium Laurate/Sodium Oleate Eutectic Mixtures
Authors: Hu Jing , Anachkov Svetoslav E. , Moaddel Teanoosh , Carnali Joseph O.
Published: October 2024

Mixtures of multiple surfactants that have superior performance to the individual components are highly sought-after commercially. Mixtures with a reduced Krafft point (TK) are particularly useful as they enable applications at lower temperatures. Such an example is the soap maker’s eutectic: the mixture of sodium laurate (NaL) and sodium oleate (NaOl). A true eutectic implies that the two surfactants do not mix in the solid state but mix readily in the micellar solution above TK, leading to a sharp TK depression at a specific composition. However, the NaL/NaOl mixture shows a broad TK depression of > 15 °C at a NaOl weight fraction (wO) of about 0.5. Our tie-line analysis shows that pure NaL and NaOl do not coexist in the solid phase on either side of the TK minimum. X-ray analysis of the isolated solids with varying wO reveals that a unique intermediate compound (I.C.) forms in the solid state with a NaL-to-NaOl mole ratio of about 4/3. Below the TK minimum, NaL and the I.C. coexist in the solids for wO < 0.5, whereas the I.C. and NaOl coexist in the solids for wO > 0.5. Each pair of solids exhibits eutectic or monotectic solubility behavior, and the congruent I.C. melting point is so close to that of the eutectic point(s) that a broad TK minimum ensues. Thermal analysis and modeling via the freezing-point depression approach support the above interpretation. The fact that surfactants with other headgroups but the same blend of chain lengths do not exhibit similar depressed TK is a topic for further study.
Effect of Chemical modification in Trigonal Gd(III) Molecular Qubits
Authors: Hansen Steen Hansgaard , Buch Christian Dirk , Weihe Høgni , Piligkos Stergios
Published: October 2024

Molecular quantum bits (qubits) are often hailed for the tunability of their properties through chemical backbone modifications. This concept has been explored in detail for transition metal-based systems. However, the effect of chemical modifications in the ligand backbone on the spin dynamics of 4f molecular qubits remains relatively unexplored. We present herein a study of the effect of the addition, and topology thereof, of methoxy groups in the ligand backbone of a Gd(III) quantum bit while maintaining the molecular symmetry. Continuous wave X-band Electron Paramagnetic Resonance on single crystals of two such derivatised Gd-based molecular qubits, give detailed information on their eigenvector composition. Their dynamic properties were examined by pulse Electron Paramagnetic Resonance on single crystals revealing that both complexes display coherent spin dynamics up to 100 K where spin-lattice relaxation limits the coherence. Furthermore, we show that tuning of the ligand field-derived anisotropy leads to control of the eigenvector composition which translates to control of the Rabi nutation frequency and hence of the time for quantum gate implementation. This demonstrates that molecular qubits offer the possibility for synthetic control and tuning of the speed of coherent manipulations.
Antibody–Bottlebrush Conjugates Unlock Diverse Payloads for Targeted Cancer Therapy
Authors: Liu Bin , Nguyen Hung , Jiang Yivan , Wang Aiden , Lensch Valerie , Sun Zehao , Boyer Zane , Raftopoulos Philip , Dai Yutong , MacNicol Piper , Wang Yuyan , Jyotsana Nidhi , Wang Wencong , Bhagchandani Sachin , Hemdev Sanjana , Shieh Peyton , Kristufek Samantha , Boucher Magalie , Downes Michael , Evans Ronald , MacMillan David , Johnson Jeremiah
Published: October 2024

Antibody drug conjugates (ADCs), which feature a monoclonal antibody (mAb) for cell targeting linked to a cytotoxic payload for cell killing, are a remarkably effective class of targeted therapeutics. Despite their success, however, ADCs typically rely on highly potent payloads, precluding the use of less potent payloads and a broader range of payload mechanisms of action (MoA).1-4 Moreover, the emerging perspective that passive targeting mechanisms play roles in ADC function in vivo suggests opportunities to engineer new ADCs based on stable prodrug scaffolds with tunable release mechanisms.5,6 Here, inspired by the physics, shape, and chemical versatility of molecular bottlebrush polymers,7-11 we introduce “Antibody–Bottlebrush prodrug Conjugates” (ABCs) as a next-generation targeted cancer therapy platform designed to enable the modular and predictable use of a broad range of payloads with varied potencies and MoAs. ABCs feature an IgG1 mAb covalently conjugated to the terminus of a compact bivalent bottlebrush prodrug (BPD) with payloads bound via cleavable linkers and hydrophilic poly(ethylene glycol) (PEG) branches on each repeat unit. This design enables the synthesis of ABCs with tunable drug-to-antibody ratios (DARs) up to two orders-of-magnitude greater than traditional ADCs without negatively impacting the physical properties of the mAb. The efficiency of ABC manufacturing is highlighted by the synthesis of >10 different variants for distinct targets (HER2 and MUC1) and with payload potencies spanning several orders-of-magnitude, imaging agents for direct ABC visualization, and photocatalysts for proximity-based labeling of the ABC interactome. ABCs display excellent target engagement, cell uptake, and efficacy in antigen expressing tumor-bearing mouse models, suggesting that they may be promising for future clinical translation.