bluuebunny/crossref_metadata_2025 huggingface dataset:
Spurway/Acid Extraction Procedures
Authors: Markus D. K.
Published: September 2022

In the article “ Spurway/Acid Extraction Procedures” by D.K. Markus (HortScience 21:217-222, Apr. 1986), the last sentence in the 2nd paragraph under the caption “ Spurway/acid extractants vs. nonacid extractants in assessing macronutrient status” should read: “ The explanation for lack of correlation is that variations occuring in plant nutrient uptake in the study were related to growth-affecting factors other than levels of macronutrients in the growth medium.”
Qualitative assessment of the development of creative industries in emerging countries: The case of Kazakhstan
Authors: Doszhan Raigul , Nussyupayeva Aygerim , Baimakhambetova Gulnara , Ashirbekova Laura , Bilan Yuriy
Published: September 2022

The creative industries sector is snowballing, and many developing countries see it as a tool for national and local development. Given the regional specificity, political narratives adopted in developed countries may not apply in economies under transition. This paper aims to evaluate the current state of creative business in emerging countries such as Kazakhstan. Adopting the design of a qualitative method, 34 semi-structured interviews were conducted with entrepreneurs and owners of small and medium-sized businesses in Kazakhstan’s creative industries. The Nvivo 10 qualitative data analysis software was used for processing the data. The interviews help to understand better the factors affecting the development of the creative industry. In general, results indicate insufficient support from government agencies, lack of accessible resources to support entrepreneurs (65% of respondents used their capital, while 17% of them were forced to apply for loans from a bank), information availability, and skills shortage. Shortage of skills is also related to the creative brain drain in Kazakhstan. One of the main problems is access to materials and technology since most of the resources are foreign-made and imported.
AcknowledgmentThe authors appreciate the grant funding for young scientists Scientific and (or) in the years 2020–2022 the MES science project number AR08052483 “Creative Industries: methodological aspects of classification and quantitative measurements in the Republic of Kazakhstan” in the framework of the budget program 217 “Development of science”.
Desbravando os Consumidores de Cerveja Artesanal: Um Estudo Sobre Hábitos e Preferências de Consumo
Authors: Ceretta Simone Beatriz Nunes , Vargas Elisandro João de , Froemming Lurdes Marlene , Günther Khetlyn , Costa Valéria Bones
Published: September 2022

O setor de cerveja artesanal, objeto deste estudo, apresenta um crescimento exponencial, principalmente por ofertar um produto de valor agregado superior, destinado a um consumidor exigente e com idiossincrasias específicas. Tomar decisões assertivas nesse segmento exige prospectar dados que estão por trás do seu comportamento, compreendendo como ele consome, quando, com quem e em que situações. Nesse contexto, o objetivo deste estudo é identificar os hábitos e preferências de consumo de consumidores de cerveja artesanal, dados estes que podem auxiliar nas tomadas de decisão dos gestores do setor. Trata-se de uma pesquisa aplicada, quantitativa, utilizando-se do método Survey de objetivo exploratório e descritivo, com o uso de procedimentos técnicos e de análise bivariada. A amostra incluiu 183 consumidores de cerveja artesanal de microrregião do RS. Os resultados mostram um consumo médio de uma vez por semana, principalmente em finais de semana, na média de um litro por pessoa, maior prevalência do consumo em casa, em momentos acompanhado de amigos, namorados(as) ou cônjuges. Os consumidores mais assíduos são homens, com remuneração média alta e que, normalmente, produzem sua cerveja e consideram o produto algo funcional, de interesse, empolgante e divertido. Os hábitos e preferências apontados pelos entrevistados criam oportunidades de adaptação dos negócios ao perfil do público-alvo, com uma tomada de decisão mais assertiva.
Bioactive Compounds as Therapeutic Intervention in Cancer Therapy
Authors: Dwarka Depika , Baijnath Himansu , Mellem John Jason
Published: September 2022

Neither transmittable nor communicable, painstakingly the second most fataldisease worldwide, cancer has gained the interest of scientists who are attempting withtenacity to decrypt its unknown facets, discover new diagnosis techniques, as well as tocreate improved and more efficient treatment methods. A major impediment toeffective cancer therapy is the inability to destroy the complete malignant tumourgrowth and evolution of tumour resistance. Chemotherapeutic drugs are known fortheir cell death mode of action, thereby incapacitating non-cancerous cells in theprocess. A successful anti-cancer drug should kill or debilitate cancer cells withoutcausing unnecessary damage to normal cells. Administration of natural bioactivecompounds exemplifies an alternative technique as they are associated with lowertoxicities. These bioactive molecules are effective and demonstrate great specificity asthey possibly operate as potent anti-oxidants and apoptosis inducers. Moderatingapoptosis might be helpful in managing, treating, or deterring cancer. Significantly,bioactive compounds are providing such templates. Plants have a long history in cancertreatment. More than 3000 species have been known for their anti-cancer potential.Over 60% of currently used anti-cancer agents are derived in one way or another fromhigher plants. This chapter describes the roles and advancements of the use of bioactivecompounds in the treatment of cancer.
Green Synthesis Application in Diabetes Therapy
Authors: Balogun Fatai O. , Sabiu Saheed
Published: September 2022

The use of medicinal plants and or medicinal plants-aided nanoparticles(NPs) in the management of diabetes mellitus has progressively received wideracceptance over the years due to the accompanying side effects with conventionaltherapy. The review explores the application of green-synthesized nanostructures in thecontrol or management of diabetes as well as probable mechanism of NPs formationand possible toxicity. Information sourced from scientific databases including ScienceDirect, Google Scholar, PubMed, Web of Science, SciFinder, JSTOR revealed 58medicinal plants explored in the synthesis of four (4) NS such as gold, silver, zincoxide and platinum with established antidiabetic potential. The NS is characterized byvarying microscopic and or spectroscopic instruments such as UV-Vis, SEM, EDS,FTIR and XRD commonly are stable, smaller-sized and mostly crystalline in nature.The functional groups responsible for the reduction and stabilization of thenanoparticles are predominantly C-O, C-H, COOH, N-H found in phenols, flavonoids,alkaloids, proteins and so on. The review identified and revealed 45% studies with lessthan 5% (mostly from India) conducted on animal models for antidiabetic and toxicitydeterminations, respectively with none for clinical studies, indicating the need forintensified efforts on research on these identified plants and unidentified species fordrug development.
Computational Applications in the Drug Discovery and Development Processes
Authors: Kaka M.O. , Aribisala J.O. , Karishma S. , Oyebamiji A.K. , Ajayeoba T.A. , Ohanaka N.J. , Sabiu S.
Published: September 2022

The traditional drug discovery and development process has been shown tobe not only time-consuming and risky, but also expensive. The identification ofdisease-related targets, the identification and optimization of novel leads, and drugdevelopment are the three critical steps in modern drug discovery. Approaches such asgenomics, proteomics, molecular biology, cell biology, structure biology,computational biology, and bioinformatics are commonly used to identify diseaserelatedtargets. Here, we appraised the significance of computational applications inmodern drug discovery and development. It was revealed that the adoption of novelcomputational technologies has proven to be efficient in identifying drug targets anddrug candidates against degenerative diseases such as diabetes, cancer and bacterialinfections, and the concept holds significant promise for a future breakthrough in drugsdiscovery, design and development. The challenges involved with computationalapplications in drug discovery are basically those of precision and accuracy in handlerand software limitations. However, future breakthroughs and effective outcomesdepend on the combination of advanced models with vast experience in the field ofdrug discovery and an understanding of the limitations of the existing computationaltools.
Pelatihan dan Pendampingan Penulisan Penelitian Tindakan Kelas Bagi Guru SMP
Authors:   Universitas Brawijaya, Hapsari Yulia , Perdhani Widya Caterine ,   Universitas Brawijaya, Hartono Didik ,   Universitas Brawijaya
Published: September 2022

Kegiatan pengabdian kepada masyarakat ini bertujuan untuk melatih dan mendampingi para guru dalam melakukan penelitian tindakan kelas dan menuliskan hasil penelitian tersebut dalam sebuah tulisan ilmiah. Para guru dibekali dengan pemahaman fundamental agar dapat melakukan praktik penelitian tindakan kelas dan praktik penulisan karya ilmiah berdasarkan hasil penelitian tersebut. Para partisipan adalah para guru bahasa Inggris di Malang. Kegiatan ini terdiri dari beberapa tahap yang dilakukan baik dengan pertemuan tatap muka maupun kelas secara daring. Hasil kegiatan inimenunjukkan bahwa para guru mempunyai pemahaman yang lebih baik dalam melakukan dan menuliskan hasil penelitian tindakan kelas yang dibuktikan dengan isi laporan penelitian mereka yang semakin baik dalam hal latar belakang penelitian dan metode penelitian. Dalam sesi daring, para guru memberikan respon sangat positif yang ditunjukkan dengan adanya diskusi dan partisipasi aktif antar peserta dan dengan tim pengabdian. Pelatihan dan pendampingan PTK terhadap guru ini secara signifikan telah berkontribusi positif dalam meningkatkan kualitaspembelajaran di dalam kelas dan kualitas guru dalam melakukan dan menuliskan hasil penelitian.
PEMETAAN PELATIHAN PENULISAN ARTIKEL ILMIAH UNTUK MENDUKUNG PROFESIONALISME GURU
Authors:   Universitas Brawijaya, Lintangsari Alies Poetri , Emaliana Ive ,   Universitas Brawijaya, Suwarso Pratnyawati Nurudi ,   Universitas Brawijaya
Published: September 2022

Instead of teaching, teachers are expected to have the ability to write scientific papers as one of the efforts to develop their professionalism. Teachers' challenges in writing scientific papers are mostly due to having limited time to conduct research and some of them are clueless to the rules of scientific paper writing. The purpose of this devotional is to map the needs of English teachers in increasing professionalism through writing scientific papers. The method employed to achieve this goal is to provide research assistance and article writing for journals at least within 30 hours. Recent devotional is a replication of the previous devotional that has been conducted in partnership with the English MGMP of SMA/SMK in Malang which has proven effective and has succeeded in assisting 6 teachers in publishing journal articles. Social engagement is applied to English teachers in kabupaten Malang dan kota Batu. Through this activity, it is expected to find the obstacles and challenges faced by English teachers in writing scientific papers to improve teacher professionalism.
SOSIALISASI PENGELOLAAN LINGKUNGAN HIDUP BERBASIS KONESP GOOD ENVIRONMENTAL GOVERNANCE MENUJU SMART ENVIRONMENT DI HIMPUNAN MAHASISWA BATANGHARI (HIMBARI)
Authors:   Universitas Jambi, Hapsa Hapsa , Baidawi Ahmad ,   Universitas Jambi
Published: September 2022

Pembangunan daerah dengan konsep smart city tidak hanya berorientasi pada ekonomi, namun juga mempertimbangkan pembangunan sumberdaya manusia dan tetap mempertimbangkan kelangsungan alam. Salah satu dimensi dari smart city adalah smart environment yang berarti pembangunan dengan tetap menjaga lingkungan, untuk konsep pembangunan berkelanjutan. Hasil dari pembangunan seharusnya tidak hanya berfokus pada pembangunan yang bersifat ekonomi, namun berpusat pada pemberdayaan masyarakat. Tujuan Kegiatan ini adalah untuk memberikan pemahaman melalui sosialisasi akan pentingnya pelestarian lingkungan hidup dengan baik. Kegiatan Pengabdian ini dimulai dari tahap diskusi kelompok, persiapan, observasi, dan sosialisasi. Metode pengabdian adalah sosialisasi, pelatihan dan simulasi. Penyampaian materi sosialisasi dan pelatihan dilaksanakan dengan beberapa metode yang relevan, yaitu: metode ceramah, tanya jawab dan diskusi. Harapan dari pengabdian ini adalah meningkatnya partisipasi masyarakat khususnya generasi muda dalam pelestarian lingkungan hidup serta tumbuh kesadaran masyarakat untuk menjaga kebersihan lingkungan dan memiliki ruang terbuka hijau bebas dari polusi sehingga dengan hal tersebut masyarakat dan generasi muda memliki jiwa yang sehat dan bersih dan terhindar dari segala penyakit yang disebabkan lingkungan kotor.
Pelatihan Penyusunan LKS berbasis AKM bagi Guru MGMP Bahasa Jepang se Malang Raya
Authors:   Universitas Brawijaya, Indrowaty Sri Aju , Febriyanti Rike ,   Universitas Brawijaya, Husna Lailatul ,   Universitas Brawijaya
Published: September 2022

The National Examination (UN), carried out so far, will be replaced in 2021 with the 2021 National Assessment. In this national assessment, three instruments are elements of the evaluation: Minimum Competency Assessment (AKM), Character Survey, and School Environment Survey. AKM itself is an assessment of essential competencies needed by all students at the elementary, junior high, and high school levels to develop their capacity and participate actively and positively in society. After the MOU with the Japanese Language MGMP in the Malang area with the Japanese Language Education Study Program, due to the Covid-19 pandemic, this collaboration can only be realised in 2021. The formulation of the problem from this Penmas is 1. How to make teaching materials (in brief) easier for students to understand the material taught in the form of worksheets? 2. How to write assignments and exercises to improve students' understanding of the themes taught in worksheets? The final result of this Penmas is the creation of AKM-based Japanese worksheets. Then these worksheets will be printed to get the ISSN/ISBN to increase the score for the promotion of available positions for teachers, while language education lecturers implement the Tri Dharma of Higher Education, namely Service.
PENINGKATAN MENTAL HEALTH DAN WELL-BEING BAGI MAHASISWA PROGRAM STUDI PENDIDIKAN BAHASA INGGRIS FIB-UB PADA MASA PANDEMI COVID-19
Authors:   Universitas Brawijaya, Degeng Putu Dian Danayanti , Kusumawardani Irene Nany ,   Universitas Brawijaya, Isnaini Moh Hasbullah ,   Universitas Brawijaya
Published: September 2022

Mental health has become a crucial issue recently among young adults (students) around the world. It is fitting that educational institutions, including in Indonesia, provide this main developmental context by equipping students with lifelong mental health and wellbeing skills. The ongoing demands on students are able to replace their capacity to cope, coupled, in most cases, with preexisting or newly manifested psychiatric symptoms. The findings of many surveys have highlighted the true severity of the student mental health crisis and are an urgent call to action for universities and government agencies because otherwise it risks an entire generation of students and the future of a nation. Regarding stigma in society, even in educational institutions themselves, the level of hiding the real problem poses a risk that tends to be higher than when we face and deal with this problem openly. Therefore, support for students’ mental health must be an immediate concern for our university leaders.
PENGENALAN KONSEP BERHITUNG BAGI PEMULA (NON FORMAL) DENGAN MEDIA WARNA-WARNI
Authors:   Institut Agama Islam (IAI) Ibrahimy Genteng Banyuwangi, Yudha Firma , Fauzi Alex Haris ,   Institut Agama Islam (IAI) Ibrahimy Genteng Banyuwangi
Published: September 2022

There was education a formal and also non formal a formal education and non formal definitely different intensity of the time that do even though the subjects given the same, an example in mathematics in the basic level. Recognition this activity aimed to provide knowledge to kids who do not school (formal), non so that they know the numbers to be able to count the base of. Method devotion is by lectures, discussion and practices. The one conducted by a team devotion in this activity is the stage, preparation and training in the implementation stage and the evaluation. From the introduction of the activities and operated the activities conducted there are 6, following are: 1) know the 1-10; 2) the rank; 3)counting the number of; 4) know the count and operation; 5) operates a sum that is using the picture; 6) operates colored using a photo of the reduction. This activity, succeded is conducted it turn out that kids love to play the media, colored although, takes time yet the sons feeling easily in the memorization and children able to operate the 1-10. Addition and subtraction in the process.
Edifícios de Elevado Perfil Ambiental em Portugal
Authors: Fernandes Eduardo de Oliveira , Santos Hugo
Published: September 2022

Nos 35 anos passados desde a publicação do célebre e fundamental “Relatório Brundtland”, pelas Nações Unidas, só foi tornada mais evidente e clara a necessidade de ação definitiva, contundente e urgente, no combate aos impactos nefastos da atividade Humana no ambiente lato sensu. E de entre essas atividades danosas, a energia usada nos, e para, os nossos ambientes construídos, é responsável, sem dúvida, direta e indiretamente, por uma das maiores parcelas. Enquanto o apelo à ação se vai ouvindo ao nível global, a ação concreta, política e executiva, tem de se fazer, a começar com o respeito e a sensibilidade pelos valores e realidades vernaculares, culturais e económicas, que o sítio exige por si e pela sua quota-parte para o todo do Planeta. É neste contexto que se justifica a oportuna necessidade deste livro, que se apresenta como uma compilação e reflexão sobre o conhecimento e experiência adquirida pelos autores, ao longo de mais de 40 anos de investigação e consultoria na articulação harmoniosa dos problemas nas áreas da energia, saúde e sustentabilidade associadas à gestão do ambiente construído português. Isto é, não deixando nenhum responsável de fora desta missão que parte da realidade da fragilidade, tantas vezes sublinhada, do ambiente em geral e do Planeta em si mesmo, que requer a solidariedade de todos. E aqui, há que combater as tentações “gadgéticas” a todos os níveis e procurarassumir a bondade das ações a empreender no sentido de satisfazer as necessidades de hoje sem descurar a salvaguarda do futuro. Ora, isto requer um rigor que não se vê na linguagem política e, infelizmente, também não na ação dos profissionais das problemáticas energéticas, ambientais e da saúde e, latu sensu, da política, como da informação e da comunicação em geral. A cacofonia das terminologias sobre a energia dá disso uma imagem confrangedora ao chamar à eletricidade “a energia”, quando aquela é apenas uma forma de energia, “simpática” é certo, mas uma forma de energia entre muitas. Por isso, Semanários e TVs de elevadas audiências deveriam ser mais cautelosos e respeitosos do tema, mesmos que isso não lhes pague mais. Tentando não cair em modas ou tendências e analisando a situação ab initio, os autores apresentam e discutem os princípios científicos base, comentam e questionam a realidade recente do desenvolvimento urbano e da construção em Portugal, invocando o vernacular e o atual, e sugerem abordagens e perspetivas que ajudarão, de forma consciente e eficaz, a transformar os espaços urbanos e os edifícios para um futuro inclusivo e amplamente respeitador dos valores sociais, económico.
PECULIARITIES OF THE ORGANISM'S REACTION TO DOSED HYPOXIA IN ELDERLY PEOPLE WITH IMPAIRED GLUCOSE TOLERANCE
Authors: Havalko Anna , Asanov Ervin , Shatilo Valerii , Antonyuk-Shcheglova Ivanna , Naskalova Svitlana
Published: September 2022

Background. The incidence of carbohydrate metabolism disorders increases with age, resulting in a significantly increased risk of cardiovascular disease. Hypoxia plays an important role in the pathogenesis of carbohydrate metabolism disorders. The aim – to establish the features of carbohydrate metabolism in hypoxia in the elderly with impaired carbohydrate tolerance.

Materials and methods. 20 elderly people with impaired glucose tolerance and 23 elderly people with preserved glucose tolerance were examined. Determined the concentration of glucose and insulin in the blood when breathing air with an oxygen content of 12%.

Results. With hypoxia in people with impaired glucose tolerance, the decrease in saturation is more significant than in people with preserved glucose tolerance. Shifts in glucose concentration in hypoxia in people with impaired glucose tolerance are greater, but the ratio of Δ glucose concentration/ΔSpO2 is higher than in people with preserved glucose tolerance. Shifts in the concentration of insulin in the blood during hypoxia did not differ in people with different glucose tolerance, but the ratio of Δinsulin concentration /ΔSpO2 in people with impaired glucose tolerance is less. In people with impaired glucose tolerance, a relationship was found between glucose levels after 120 minutes of glucose tolerance test and SpO2 shifts in hypoxia, as well as a relationship between HOMA index and SpO2 shifts in hypoxia.

Conclusions. Elderly people with impaired glucose tolerance have reduced resistance to hypoxia and increased utilization of glucose in hypoxia, due to smaller changes in insulin concentrations. At the same time at them disturbance of a carbohydrate metabolism depends on resistance to a hypoxia.
АНАЛІЗ ЖИРНОКИСЛОТНОГО СПЕКТРУ ВІЛЬНИХ ЖИРНИХ КИСЛОТ СИРОВАТКИ КРОВІ ТА ПОКАЗНИКІВ ЛІПІДІВ У ХВОРИХ НА ЦУКРОВИЙ ДІАБЕТ 2 ТИПУ ЯК СКЛАДОВА МЕТАБОЛОМІЧНОГО ПРОФІЛЮВАННЯ ПРИ ТЕРАПІЇ ДАПАГЛІФЛОЗИНОМ
Authors: Kushnarova Nataliia , Зінич Олеся , Прибила Ольга , Ковальчук Алла , Корпачев Вадим , Шишкань-Шишова Катерина
Published: September 2022

Обґрунтування: Оцінка спектру жирних кислот (ЖК) як частини метаболомічного профілювання може спрогнозувати кардіоваскулярні ускладнення цукрового діабету (ЦД) 2 типу ще до появи клінічних симптомів, а кількісне визначення багатьох ЖК та оцінка їх відносних рівнів в динаміці лікування захворювання можуть дати більш повну картину метаболізму ЖК, ніж дослідження кількох окремих ЖК.
Мета дослідження: метаболомічне профілювання вільних жирних кислот сироватки крові хворих на ЦД 2 типу з дисліпідемією, з метою порівняння жирнокислотного профілю до і після курсу лікування дапагліфлозином.
Матеріали та методи. Обстежено 30 хворих на ЦД 2 типу з дисліпідемією, віком більше 45 років, з рівнем HbA1c>7,5% на тлі прийому 2000 мг метформіну. У пацієнтів визначали показники вуглеводного обміну, ліпідного спектру сироватки крові. За допомогою газо-рідинної хроматографії визначали жирнокислотний склад вільних жирних кислот (ВЖК).
Результати: Після лікування пацієнтів дапагліфлозином впродовж 1 року достовірно знизився рівень холестерину, тригліцеридів та ВЖК без збільшення дози статинів, проте не спостерігалось достовірних змін у інших фракціях ліпідів. Зафіксовані також достовірні зміни індексу вісцерального ожиріння, що свідчить про зниження ризику атерогенезу та поліпшення функції вісцеральної жирової тканини. Виявлено, що в результаті лікування відбулося достовірне зниження не лише кількості ВЖК, а й зміни їх жирнокислотного спектру, а саме, перерозподіл співвідношення насичених і ненасичених ЖК у бік зниження ступеня насиченості за рахунок зменшення вмісту пальмітинової, стеаринової та міристинової кислот та зростання ненасиченості за рахунок підвищення частки мононенасиченої пальмітолеїнової та поліненасиченої арахідонової кислот.
Висновки. Показано, що вплив терапії дапагліфлозином у пацієнтів з цукровим діабетом типу 2 та дисліпідемією проявився у підвищенні відношення сумарної кількості ненасичених жирних кислот до насичених жирних кислот у фракції вільних жирних кислот на тлі зниження рівня холестерину та тригліцеридів. Крім того, зниження вмісту лінолевої кислоти у фракції вільних жирних кислот може вказувати на поліпшення її конверсії на арахідонову, яка є попередником ейкозаноїдів з протизапальними, вазоділятаційними, нейротропними властивостями. Отже, застосування дапагліфлозину не лише сприяє корекції порушень ліпідного спектру сироватки крові, а також за рахунок зміни якісного складу вільних жирних кислот покращує іх біодоступність до β-окислення у печінці, що свідчить про вплив дапагліфлозину на метаболомічному рівні та надає нові уявлення про дію цього препарату.
OTHER POSITRON EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY TRACERS IN DIFFERENTIAL THYROID CARCINOMA ¡BEYOND THE USE OF 2-[18F]FDG
Authors: Acuña Hernandez Marylin , Vallejo Armenta Paola , Cancino Ramos Uvi , Sánchez Ordúz Liset , Casanova Triviño Pamela , Cadavid Blanco Leonardo
Published: September 2022

Thyroid cancer is a common endocrinological malignancy worldwide, accounting for 3% of the global incidence of all cancers. Meta-analyses, systematic reviews, and descriptive reviews mention the use of positron emission tomography / computed tomography (PET/CT) as an alternative to morphological imaging such as computed tomography or magnetic resonance imaging to clarify the diagnosis. The aim: analysis of positron emission tomography/computed tomography tracers in the differential diagnosis of thyroid carcinomas.
Materials and methods: Review about PET/CT tracers different than 2-[18F] fluorodeoxyglucose (FDG) in patients with diagnosed differentiated thyroid carcinoma.
Evidence Synthesis: PET/CT is an alternative to morphological diagnosis imaging when is inconclusive or negative due to the suspicion of tumor persistence or recurrence, elevation of tumor markers, dedifferentiation thyroid carcinoma, non-conventional therapeutic options. 2-[18F] FDG is the most uses a tracer, but there are scenarios where can be negative or inconclusive, for this reason, in recent years other PET tracers have been used: [124I] NaI, [18F] Tetrafluoroborate, [68Ga] Ga-NOTE-PRGD2 or [18F] AIF-NOTE-PRGD2, [68Ga] Ga-DOTA-FAPI, [18F] Fluorocholine or [11C] C-Choline, [18F] or [68Ga] Ga-PSMA, [68Ga] Ga DOTA-TATE/TOC/NOC/LAN, [18F]-FAZA, L-[methyl-11C] Methionine and [89Zr] DFO-PAS200-Fab.
Conclusions. There are multiple radiopharmaceuticals different than 2-[18F] FDG, which can be adequate in the context of differentiated thyroid carcinoma: 2-[18F] FDG PET/CT negative, TENIS syndrome, radioiodine-refractory thyroid cancer suspected, thyroid dedifferentiated carcinoma, and some cases theragnostic tools.
Profile of blood donors in a hemotherapy institution in Midwestern Brazil
Authors: Ferreira Abreu Weldson , Silva Leticia Aparecida , Sousa Polyanna Campos Gonçalves
Published: September 2022

Objective: To describe the profile of blood donors in a hospital in the Midwest of Brazil with its own blood bank to have a diagnostic view of the establishment and enable the planning of improvements in services. Methods: This is a descriptive, retrospective study with a quantitative approach. A proportional stratified sampling technique was used, with a confidence level of 95% and a margin of error of 5%, to represent and characterize the study population, obtaining a sample of 363 donors. Subsequently, a proportional allocation was performed in the established groups (fit donors, unfit donors, and platelet apheresis donors). Results: The profile of eligible donors in the institution studied was composed of married (55.2%), male (63.7%), aged between 20 and 30 years (40.4%), with O RhD+ blood (46.7%) and A RhD+ (29.6%) more prevalent. Apheresis platelet donors (50%) are single, female (81.3%), and aged between 31 and 40 years (43.8%). As for unfit donors, 94.8% are temporary-unfit donors, married donors (53.2%), female (54.5%), and between 20 and 40 years old (54.6%), with the categories of health condition and lifestyle being the most prevalent reasons for disability. Conclusion: There is a hegemony for replacement and first-time donors, showing the effectiveness of the solidarity policy implemented in the institution, but it shows the low effectiveness in the loyalty of these donors.
Effect of different manipulations of the cluster-set method on training volume and time under tension in resistance training men
Authors: Dinardi Ricardo Reis , Tourino Frank Douglas , De Lacerda Lucas Túlio , Ferreira-Júnior João Batista , Martins-Costa Hugo César
Published: September 2022

Objective: To compare the acute effect of two training protocols until concentric failure (CF) with different intra-set interval (ISI) configurations (20 s and 40 s) on total weight, the total number of repetitions, and time under tension in trained subjects. Methods: Ten men participated in the study (age = 25.1 ± 4.4 years; body mass = 76.5 ± 10.4 kg; height = 175.8 ± 9.3 cm). Two protocols were performed with 4 sets of bench press exercises and differentiated by the ISI: i) Protocol ISI-40 (40 s) - each set consisted of 6 repetitions followed by an ISI of 40 s and completed with repetitions up to CF; ii) Protocol ISI-20 (20 s) - each set consisted of 6 repetitions with ISI of 20 s every 3 repetitions followed by repetitions to CF. The intensity was 10 repetitions maximum, and the rest interval between sets of 80 s. A minimum interval of 48 h was adopted between protocols. Results: There was no significant difference in the number of repetitions (p = 0.074), in the time under tension (p = 0.353) and in the total volume (p = 0.083) between the protocols. Conclusion: The results indicate that the different ISI configurations did not distinctly influence the number of repetitions, time under tension, and total volume.
Health profile of the elderly person accompanied by the family health strategy in a countryside of Ceará - Brazil
Authors: Almeida José Rogécio de Sousa , Solano Lorrainy , Freire Marco Aurelio M , Oliveira Lucidio C
Published: September 2022

Objective: To evaluate the correlation between functional dependence and emotional state, cognitive function, and ambulation of the elderly people accompanied by a family health team. Methods: A cross-sectional, quantitative, and prospective study was conducted in the city of Quixeré/CE between August 2020 and April 2021. Participated in 229 elderly people registered in the Family Health Strategy teams evaluated using the Lawton scale, MMSE, GDS-15, and Tinneti test. The association of variables was verified using the chi-square or Fisher's exact tests. Odds Ratio (95%CI) were calculated, followed by logistic regression using the Hosmer and Lemeshow test. Results: The sample was primarily composed of women with low education, average age of 70 years, and a high demand for primary health services. Women were more vulnerable to depression, with no difference in falls related to sex. Age was a risk factor for all aspects evaluated. There was a correlation between functional dependence and all aspects analyzed. There was a relationship between the level of functional dependence and education (OR: 2.0; 95%CI: 0.05 - 78.32), living in the rural area (OR: 2.83; 95%CI: 1.6 - 5.1), depression (OR: 5.18; 95%CI: 1.2 – 22.8) and risk of falls (OR: 1.67 CI: 0.8 – 3.5), with the last two factors remaining significant in the logistic regression. Conclusion: Functional dependence to more complex daily activities among the elderly was significant, with an essential relationship with emotional and cognitive aspects and risk of falls.
Patriarchy as Ideology: An Examination of Marxist Feminism
Authors: Duan Jiale
Published: September 2022

Marxist feminist scholars have gone through a rather long and tortuous process of understanding the capitalist system and patriarchy. At first, they argued that the capitalist system and patriarchy go hand in hand and together keep women in subservient positions. Later, they examined related concepts and argued that the capitalist system and patriarchy merge and intensify the oppression of women. At the same time, later Marxist feminist scholars returned to Marxist theory and suggested that the capitalist system is the key to the current women’s problems and patriarchy is its ideological tool to defend the ruling class’s interests.
Estimation of Pralatrexate by Simple and Fast Reverse Phase High Performance Liquid Chromatographic Method
Authors: Kulsum Syeda , Naz Ayesha , Zareen Misbah , Noor Amatul
Published: September 2022

Abstract: A simple, specific, precise, accurate, and sensitive Reverse Phase High Performance Liquid Chromatographic method has been developed for the determination of Pralatrexate in both pure and pharmaceutical dosage forms. In this method Agilent (4.6×150mm) 5µ column in isocratic mode with mobile phase containing water: methanol (25:75% v/v) was selected. The effluents were monitored at 300 nm and flow rate was fixed as 1.4 ml / min. The retention time was 3.312 min. The linearity was in the range of 20-100 g / ml. This method was validated for linearity, precision, limit of detection, limit of quantification and accuracy. Statistical analysis proves that the method is precise, reproducible and selective for the estimation of the pralatrexate drug
To Study the Behavior of Concrete by Replacement of Fine Aggregate with Granite Powder and Cement with Tobacco Waste Ash
Authors: Sharma Sunandan , Lalotra Sourabh
Published: September 2022

Abstract: Environmental concerns caused by the extraction of raw materials and CO2 emissions in the production of Portland cement led to pressures to reduce the consumption of this constituent of concrete, combined with the need to increase its durability. The cement is the most costly and energy intensive component of concrete. The unit cost of concrete can be reduced as much as possible by partial replacement of cement with other waste pozzolanic materials. Certain materials of mineral origin are also added to concrete to enhance their strength and durability properties of concrete materials such as Granite Powder and other by TWA.
An Experimental Study on the Behavior of Concrete by Using Tobacco Waste Ash and Spent Fire Bricks
Authors: Sharma Sunandan , Lalotra Sourabh
Published: September 2022

Abstract: Nowadays, there is an increasing curiosity within the development of eco-friendly materials. Tobacco waste ash displays properties such as fineness, amorphous form and high silica content and thus needs to be investigated with its potential to show high pozzolanic activity The usage or replacement of fire bricks is periodical in nature in metallurgical based industries. The fire bricks cast out off after use are called as Spent Fire Bricks. The Spent Fire Brick which are the waste should be through properly without causing environmental problematics in the vicinity of dump. Usually the waste materials are cast out by land filling. In the analogous manner the spent fire bricks are also used as land filling material degrading the environment. Certain materials of mineral origin are also added to concrete to enhance their strength and durability properties of concrete materials such as Spent Fire Bricks and other by TWA.
How Does Profitability, Size, and Capital Affect Credit Risk?: Evidence from Islamic Banks in Asian Countries
Authors: Zuhroh Idah
Published: September 2022

The study aims to analyze the effect of profitability, size, and capital on the credit risk of Islamic banks in Asian countries through the mediating variable of financing by path regression analysis. Data were obtained quarterly from 2015Q1 – 2020Q3. Method of the study usedcausal research design, namely research that has the main objective of proving a a relationship affecting and being influenced by the variables studied. The findings conclude that size and profitability significantly affect credit risk through the financing mediation variable.  Capital does not significantly reduce credit risk because it only functions to mediate financing. Meanwhile, increased financing will also increase the credit risk of Islamic banks in the Asian Region. The study can explain why there is an inconsistency of the effect profitability, size, capital, on credit risk because there is a financing mediation role. The implication of policy that the Islamic bankers in Asian countries must more prudent to manage financing so that credit risk is controlled.
Critical Analysis on Business Innovation for Traders During Pandemic Covid-19: An Islamic Economics Perspective
Authors: Surahman Maman , Srisusilawati Popon , Hadiyanto Redi , Ambarwati Tri , Maharis Fadilah Reyhan
Published: September 2022

This study aims to analyze business innovation in Islam Economics to the sustainability of traders around UNISBA during pandemic Covid-19. This study was qualitative using descriptive analytical approach. Type of data collected was primary data obtained from interview. The data analysis technique used was descriptive model qualitative in shape data collection, data reduction, data display, and conclusion. The result found that traders can continue their business by using e-marketing and online marketplace which considered necessary to be implemented, especially in the Covid-19 pandemic situation. The contribution of this research to enhance the development of science and business practice in the implementation of e-marketing dan online marketplace.
Faktor Yang Mempengaruhi Tingkat Pengangguran di Beberapa Negara ASEAN
Authors: Ghifari Dimas Bayu Patra  , Nuraini Ida , Fuddin Muhammad Khoirul
Published: September 2022

This study aims to determine the effect of economic growth, population and inflation on unemployment rates in five ASEAN countries. This study uses a quantitative approach method. The data analysis tool used is multiple linear regression analysis using panel data through the help of Software Eviews 9. The results of this study indicate that partially, the economic growth variabel has a negative and significant effect on unemployment, the population variabel has a negative and significant effect on unemployment. Inflation has a positive and significant effect on unemployment. Simultaneously, economic growth, population and inflation have a positive and significant impact on unemployment in five ASEAN countries in 2009-2020.
Analisis PDRB 34 Provinsi di Indonesia Pada Masa Pemerintahan Presiden Joko Widodo
Authors: Ahrizal Ghaly Rizquillah
Published: September 2022

This study is intended to analyze the direct influence of education, labor, information and communication technology development index (ICT-DI), and domestic investment (DI) on the gross regional domestic product (GRDP) of 34 provinces in Indonesia during the government period. President Joko Widodo. This study uses secondary data in the form of panel data, 2015-2020, using the variables of average length of school, working population, information and communication technology development index (ICT-DI), and domestic investment (DI). The analytical method used is Ordinary Least Square (OLS). The results showed that education and manpower had a significant effect on the GRDP of 34 provinces in Indonesia, while the ICT development index and DI did not significantly affect the GRDP of 34 provinces in Indonesia. For this reason, the government should be able to intensify the development of communication infrastructure and provide various trainings, especially for residents in archipelagic provinces, so that the value of ICT-DI can be increased. and also the government to get domestic investment as much as possible can be maximized again because, high and stable DI can help Indonesia in economic development.
Analisis Pendapatan Pedagang Batu Intan Permata Sebelum dan Pada Saat Pandemi Covid-19 di Pasar Martapura Kalimantan Selatan
Authors: Sardanah Nor Mila Ayu , Malik Nazaruddin , Arifin Zainal
Published: September 2022

Penelitian ini bertujuan untuk mengetahui dan menganalisis hasil penjualan Batu Intan pada sebelum dan pada saat Pandemi Covid-19 di Pasar Martapura Kalimantan Selatan dan Untuk mengetahui apakah ada perbedaan penjualan Batu Intan peramata sebelum dan pada saat pandemi Covid-19 di Pasar Martapura Kalimantan Selatan. Penelitian ini merupakan deskriptip kuantitatif, Variabel yang digunakan dalam penelitian ini yaitu pendapatan yang diperoleh pedagang batu intan di Pasar Martapura. Sampel yang digunakan dalam penelitian ini yaitu pedagang batu intan. Teknik analisis data menggunakan kuisioner dan wawancara , yaitu dengan membuat daftar pernyataan tertulis yang telah disusun (kuisioner terbuka). Analisis kuantitatif digunakan untuk menjabarkan hasil dari kuisioner yang telah didapatkan untuk menjabarkan hasil dari kuisioner yang didapatkan dari responden dalam bentuk angka. Hasil penelitian ini yaitu adanya perbedaan pendapatan yang sangat drastis oleh pedagang batu intan di Pasar martapuka Kalimantan Selatan sebelum dan pada saat pandemi Covid-19
Perbandingan dan Representasi Feminisme Eksistensialis dalam Novel Berlatar Papua Berjudul Namaku Teweraut dan Tanah Tabu
Authors: Rahman Fauzi
Published: September 2022

Penelitian ini bertujuan membandingkan serta merepresentasikan feminisme eksistensialis dalam novel berjudul Namaku Teweraut karya Ani Sekarningsih dengan novel Tanah Tabu karya Anindhita S. Thayf. Metode yang digunakan dalam penelitian ini adalah deskriptif kualitatif dengan pendekatan sastra perbandingan. Analisis data atau prosedur analisis penelitian dilakukan dengan cara membaca keseluruhan novel, menandai bagian-bagian yang dianggap sesuai dengan sasaran kajian feminisme eksistensialis, mereduksi bagian yang tidak termasuk kajian feminisme eksistensialis, mengklasifikasikan persamaan dan perbedaan hasil analisis, hingga menarik simpulan. Hasil penelitian menunjukkan bahwa novel Namaku Teweraut merepresentasikan suku Asmat yang masih menganut sistem poligami, perjodohan, perempuan tidak boleh mengambil keputusan atau memilih jalan hidupnya dan mengabaikan pentingnya pendidikan. Adapun novel Tanah Tabu mengisahkan suku Dani yang mengesampingkan pendidikan dan mengutamakan pernikahan karena perempuan tidak perlu belajar cukup mengurus keluarga dan patuh pada suami. Dalam kedua novel ini dijelaskan bahwa tokoh wanita tidak bisa mengenyam pendidikan secara bebas karena terikat dengan sistem patriarki.
Factors Affecting the Life Satisfaction of Multicultural Adolescents According to Gender: Self-Perception and Relational Aspects
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Sangmi
Published: September 2022

Objectives This study aimed to explore the factors that affected life satisfaction in multicultural adolescents according to gender in terms of self-perception and relational aspects.
Methods The data used in this study were from the eighth wave of the Multicultural Adolescents Panel Study conducted by the National Youth Policy Institute. Multiple logistic regression analysis was performed using SPSS version 28.0. In step 1, self-perception factors were analyzed. In step 2, self-perception, relational factors, and general characteristics were analyzed.
Results In step 1, self-esteem had the greatest influence on life satisfaction in both boys (β=.32, p<.001) and girls (β=.43, p<.001). In step 2, parental support had the largest effect of the relational factors on life satisfaction in both boys (β=.12, p=.003) and girls (β=.11, p=.005). The factors that most affected life satisfaction according to gender were national identity (β=.09, p=.011) and residence in large cities (β=-.09, p=.006), which disproportionately affected boys, and a poor perceived household economic status (β=-.08, p=.011) and the number of close friends (β=.07, p=.038), which disproportionately affected girls.
Conclusions Efforts to improve the life satisfaction of multicultural adolescents should include strategies to enhance self-perception and parental support and consider gender differences.
Keyword Network Analysis of Domestic Research Trends on the Journal of the Work-Study Combination in Korea
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Woo Ki Jung , Lee Eun-taek
Published: September 2022

Objectives The purposes of this study was to propose future research direction by analyzing the research trends on the journal of the ‘work-study combination’ in Korea.
Methods 110 domestic researches of the work-study combination published from 2013 to March of 2022 in Korea were examined the characteristics of the subjects and methods. Then keywords of researches except ‘work-study combination’ that is commonly used were performed by the keyword network analysis to analyze keyword network structure and centrality by using Gephi 0.9.
Results Papers were published mainly in 2019 and 2020, when the ‘Work-Study Combination Act’ was enacted and implemented. It was focused on commitment, satisfaction, performance in participating company as well as the education and training method and program design of the work-study combination. In particular ‘apprenticeship training’ was highly positioned at degree, eigen vector, closeness, and betweenness centrality.
Conclusions The ‘work-study combination’ in Korea has been conducted not by the industry but the government in a short time. In order to take root in industry as a healthy vocational education and training model as well as qualitative growth in the future, spontaneous movement of the key members like as business owner, corporate on-site trainer, participating employee is mostly needed. Also it is necessary to study the methodological discussions on apprenticeship training and the experiences of the participating employee who is not a simple participant as employee but a positive participant who has willing to trained.
Analysis on the Inquiry Tendency of the Social Studies Textbooks in Elementary School: Based on Romey Technique
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Rhee Seo young
Published: September 2022

Objectives According to the 2015 revised curriculum, elementary school social studies textbooks were issued and used by the nation, and the method of issuance was changed to the authorization system in 2021, so 3rd and 4th graders in elementary school used the authorized textbooks from 2022. Social studies emphasizes inquiry from ‘character’ and ‘goals’ in the 2015 revised curriculum. Therefore, I would like to examine whether the authorized textbook has an inquiry tendency according to the purpose of the curriculum.
Methods In this study, the inquiry tendency of elementary school social studies government-designated textbook and six authorized textbooks was analyzed using the Romey technique. The Romey analysis technique quantitatively determines the inquiry tendency of the textbooks by calculating the evaluation index based on the texts, figures and diagrams, activities, and questions.
Results The text analysis rating index was all high except for the two types. In the Figure and diagram analysis, activities index, and analysis questions at chapter ends, the inquiry tendecy was all shown to be an exploratory textbook. It can be seen that the overall evaluation index is less than 1, so that students can fully understand the content and apply it to learning activities through textbooks.
Conclusions The possibility of student exploration was seen in the text, data, activities, and questions. However, authoritative and non-exploratory textbooks are still provided to students in the composition of the text. Accordingly, it is hoped that the text of elementary school social studies textbooks can be transformed into an exploratory tendency that can interest students and start solving problems.