bluuebunny/crossref_metadata_2025 huggingface dataset:
Heterocyclic Iminoquinones and Quinones from the National Cancer Institute (NCI, USA) COMPARE Analysis
Authors: Haji Naemah , Faizi Masoma , Koutentis Panayiotis A. , Carty Michael P. , Aldabbagh Fawaz
Published: July 2023

This review uses the National Cancer Institute (NCI) COMPARE program to establish an extensive list of heterocyclic iminoquinones and quinones with similarities in differential growth inhibition patterns across the 60-cell line panel of the NCI Developmental Therapeutics Program (DTP). Many natural products and synthetic analogues are revealed as potential NAD(P)H:quinone oxidoreductase 1 (NQO1) substrates, through correlations to dipyridoimidazo[5,4-f]benzimidazoleiminoquinone (DPIQ), and as potential thioredoxin reductase (TrxR) inhibitors, through correlations to benzo[1,2,4]triazin-7-ones and pleurotin. The strong correlation to NQO1 infers the enzyme has a major influence on the amount of the active compound with benzo[e]perimidines, phenoxazinones, benz[f]pyrido[1,2-a]indole-6,11-quinones, seriniquinones, kalasinamide, indolequinones, and furano[2,3-b]naphthoquinones, hypothesised as prodrugs. Compounds with very strong correlations to known TrxR inhibitors had inverse correlations to the expression of both reductase enzymes, NQO1 and TrxR, including naphtho[2,3-b][1,4]oxazepane-6,11-diones, benzo[a]carbazole-1,4-diones, pyranonaphthoquinones (including kalafungin, nanaomycin A, and analogues of griseusin A), and discorhabdin C. Quinoline-5,8-dione scaffolds based on streptonigrin and lavendamycin can correlate to either reductase. Inhibitors of TrxR are not necessarily (imino)quinones, e.g., parthenolides, while oxidising moieties are essential for correlations to NQO1, as with the mitosenes. Herein, an overview of synthetic methods and biological activity of each family of heterocyclic imino(quinone) is provided.
The Molecular Model of Organic Matter in Coal-Measure Shale: Structure Construction and Evaluation Based on Experimental Characterization
Authors: Li Kunjie , Tian Hongwu , Liang Yanxia , Guo Wei , Zhao Yuqiong , Meng Yanjun , Kong Shaoqi
Published: July 2023

To investigate the molecular structure and micropore structure of organic matters in coal-measure shale, the black shale samples of the Shanxi formation were collected from Xishan Coalfield, Taiyuan, and a hybrid experimental–simulation method was used for realistic macromolecular models of organic matter (OM). Four experimental techniques were used to determine the structural information of OM, including elemental analysis, state 13C nuclear magnetic resonance (13CNMR), X-ray photoelectron spectroscopy (XPS), and Fourier transform infrared spectroscopy (FTIR). With structural parameters, two-dimensional (2D) average molecular models of OM were established as C177H160O8N2S with a molar weight of 2474, which agreed well with the experimental 13C-NMR spectra. A realistic three-dimensional (3D) OM macromolecular model was also reconstructed, containing 20 2D molecules with a density of 1.41 g/cm3. To determine the connectivity and spatial disposition of the OM pores, focused ion beam microscope (FIB-SEM) and transmission electron micrographs (TEM) were utilized. The 3D OM pores models were developed. The results show that whether the OM pores varied from 20 to 350 nm as obtained from FIB-SEM images or less than 10 nm as observed in the TEM images, both were of poor connectivity. However, the ultra-micro pores from the 3D OM macromolecular model varied from 3Å to 10 Å and showed certain connectivity, which may be the main channel of diffusion. Furthermore, with the pressure increased, the methane adsorption capacity of the 3D OM model increased with a maximum value of 103 cm3/g at 7 MPa, indicating that OM pores less than 1 nm have a huge methane adsorption capacity. Therefore, our work provides an analysis method that is a powerful and superior tool in further research on gas migration.
Effects of Chitosan and Cellulose Derivatives on Sodium Carboxymethyl Cellulose-Based Films: A Study of Rheological Properties of Film-Forming Solutions
Authors: Zhang Huatong , Su Shunjie , Liu Shuxia , Qiao Congde , Wang Enhua , Chen Hua , Zhang Cangheng , Yang Xiaodeng , Li Tianduo
Published: July 2023

Bio-based packaging materials and efficient drug delivery systems have garnered attention in recent years. Among the soluble cellulose derivatives, carboxymethyl cellulose (CMC) stands out as a promising candidate due to its biocompatibility, biodegradability, and wide resources. However, CMC-based films have limited mechanical properties, which hinders their widespread application. This paper aims to address this issue by exploring the molecular interactions between CMC and various additives with different molecular structures, using the rheological method. The additives include O-carboxymethylated chitosan (O-CMCh), N-2-hydroxypropyl-3-trimethylammonium-O-carboxymethyl chitosan (HTCMCh), hydroxypropyltrimethyl ammonium chloride chitosan (HACC), cellulose nanocrystals (CNC), and cellulose nanofibers (CNF). By investigating the rheological properties of film-forming solutions, we aimed to elucidate the influencing mechanisms of the additives on CMC-based films at the molecular level. Various factors affecting rheological properties, such as molecular structure, additive concentration, and temperature, were examined. The results revealed that the interactions between CMC and the additives were dependent on the charge of the additives. Electrostatic interactions were observed for HACC and HTCMCh, while O-CMCh, CNC, and CNF primarily interacted through hydrogen bonds. Based on these rheological properties, several systems were selected to prepare the films, which exhibited excellent transparency, wettability, mechanical properties, biodegradability, and absence of cytotoxicity. The desirable characteristics of these selected films demonstrated the strong biocompatibility between CMC and chitosan and cellulose derivatives. This study offers insights into the preparation of CMC-based food packaging materials with specific properties.
A Modified BRDF Model Based on Cauchy-Lorentz Distribution Theory for Metal and Coating Materials
Authors: Guo Fengqi , Zhu Jingping , Huang Liqing , Li Haoxiang , Deng Jinxin , Zhang Xiangzhe , Wang Kai , Liu Hong , Hou Xun
Published: July 2023

This paper presents a modified Bidirectional Reflectance Distribution Function (BRDF) model based on the Cauchy–Lorentz distribution that accurately characterizes the reflected energy distribution of typical materials, such as metals and coatings in hemispherical space. The proposed model overcomes the problem of large errors in classical models when detecting angles far away from the specular reflection angle by dividing the reflected light into specular reflection, directional diffuse reflection, and ideal diffuse reflection components. The newly added directional diffuse reflection component is represented by the Cauchy–Lorentz distribution, and its parameters are directly obtained from experimental measurement curves without distribution fitting. Surface morphology and model parameters are determined through measurements, and the comparison between simulation and actual measurement results shows that the modified BRDF model is in excellent agreement with the measured data. The proposed model not only achieves higher accuracy and universality, but it also represents a significant advancement in the field of BRDF modeling research. Its contributions have profound implications for advancing the state of the art in BRDF modeling, as well as having a broader impact on computer graphics and computer vision domains.
Plant Growth Regulators and Activated Charcoal Selectively Affect Phenylethanoid and Flavone Glycoside Accumulation in Sideritis scardica Griseb. Tissue Culture
Authors: Danova Kalina , Stanoeva Jasmina Petreska , Aneva Ina , Alipieva Kalina , Stefova Marina
Published: July 2023

Sideritis scardica Griseb. is a Balkan endemic species traditionally used for the treatment of pulmonary emphysema and angina pectoris. Recent research has also shown its phytotherapeutic potential as an anticancer and neuroprotective agent. These findings, as well as the endangered status of the species in its wild habitats, have motivated the present research on application of plant cell tissue and organ culture for the purposes of both valuable germplasm conservation and secondary metabolites production. Shoot cultures of the plant were initiated from sterile germinated seeds and the effects of activated charcoal (AC), as well benzyl adenine and 1-naphthaleneacetic acid treatments, were experimented. The phenolic profile analysis was performed by HPLC/DAD/MSn. Comparison with samples collected from wild plants in their natural habitat was performed. It was established that in vitro multiplication induced by plant growth regulators (PGRs) was accompanied by a higher impairment of leaf morphology and trichome formation, as well as by the occurrence of plantlet hyperhydricity and callus formation, as compared with the AC treatments. Shoot culture-derived plant material was shown to produce two phenylethanoids and five flavone glycosides, not detected in the wild collected plant material. In addition, the two types of in vitro culture treatments led to the stimulation of either flavone glycosides or phenylethanoids in the in vitro cultivated plants. Thus, AC stimulated, to a higher extent, flavone glycosides’ accumulation, leading to an elevated flavone/phenylethanoid ratio, as compared with PGR treatments.
Effect of Light of Different Spectral Compositions on Pro/Antioxidant Status, Content of Some Pigments and Secondary Metabolites and Expression of Related Genes in Scots Pine
Authors: Pashkovskiy Pavel , Ivanov Yury , Ivanova Alexandra , Kartashov Alexander , Zlobin Ilya , Lyubimov Valery , Ashikhmin Aleksandr , Bolshakov Maksim , Kreslavski Vladimir , Kuznetsov Vladimir , Allakhverdiev Suleyman I.
Published: July 2023

The aim of this study was to investigate the effect of light quality (white fluorescent light, WFL, containing UV components), red light (RL, 660 nm), blue light (BL, 450 nm), and white LED light (WL, 450 + 580 nm) on the components of the cellular antioxidant system in Pinus sylvestris L. in needles, roots, and hypocotyls, focusing on the accumulation of key secondary metabolites and the expression of related genes. The qualitative and quantitative composition of carotenoids; the content of the main photosynthetic pigments, phenolic compounds, flavonoids (catechins, proanthocyanidins, anthocyanins), ascorbate, and glutathione; the activity of the main antioxidant enzymes; the content of hydrogen peroxide; and the intensity of lipid peroxidation (MDA and 4-HNE contents) were determined. RL resulted in an increase in the content of hydrogen peroxide and 4-HNE, as well as the total fraction of flavonoids in the needles. It also enhanced the expression of several PR (pathogen-related) genes compared to BL and WL. WFL increased the content of phenols, including flavonoids, and enhanced the overall activity of low-molecular antioxidants in needles and hypocotyls. BL increased the content of ascorbate and glutathione, including reduced glutathione, in the needles and simultaneously decreased the activity of peroxidases. Thus, by modifying the light quality, it is possible to regulate the accumulation of secondary metabolites in pine roots and needles, thereby influencing their resistance to various biotic and abiotic stressors.
A Methodology for Consolidation Effects of Inventory Management with Serially Dependent Random Demand
Authors: Huerta Mauricio , Leiva Víctor , Rojas Fernando , Wanke Peter , Cabezas Xavier
Published: July 2023

Most studies of inventory consolidation effects assume time-independent random demand. In this article, we consider time-dependence by incorporating an autoregressive moving average structure to model the demand for products. With this modeling approach, we analyze the effect of consolidation on inventory costs compared to a system without consolidation. We formulate an inventory setting based on continuous-review using allocation rules for regular transshipment and centralization, which establishes temporal structures of demand. Numerical simulations demonstrate that, under time-dependence, the demand conditional variance, based on past data, is less than the marginal variance. This finding favors dedicated locations for inventory replenishment. Additionally, temporal structures reduce the costs of maintaining safety stocks through regular transshipments when such temporal patterns exist. The obtained results are illustrated with an example using real-world data. Our investigation provides information for managing supply chains in the presence of time-patterned demands that can be of interest to decision-makers in the supply chain.
Slow-Time MIMO Waveform Design Using Pulse-Agile-Phase-Coding for Range Ambiguity Mitigation
Authors: Chang Shaoqiang , Yang Fawei , Liang Zhennan , Ren Wei , Zhang Hao , Liu Quanhua
Published: July 2023

This paper proposed a Pulse-Agile-Phase-Coding slow-time MIMO (PAPC-st-MIMO) waveform, where the phase-coded signal is utilized as the intra-pulse modulation of the slow-time MIMO waveform. Firstly, the signal model of the proposed waveform is derived. To improve the orthogonality of the phase-coded waveform sets, a novel hybrid evolutionary algorithm based on Cyclic Algorithm New (CAN) is proposed. After the optimization process of the phase-coded waveform sets, the signal processing method of the PAPC-st-MIMO waveform is derived. Finally, the effectiveness of the proposed method is verified with a simulation experiment. The mitigation ratio of the near-range detection waveform can achieve −30 dB, while the long-range detection waveform can achieve −35 dB. This approach ensures waveform orthogonality while enabling the slow-time MIMO waveform to achieve distance selectivity. By conducting joint pulse-Doppler processing across multiple range segments, range ambiguity can be suppressed, increasing the system’s Pulse Repetition Frequency (PRF) without introducing ambiguity.
Application of Data Sensor Fusion Using Extended Kalman Filter Algorithm for Identification and Tracking of Moving Targets from LiDAR–Radar Data
Authors: Montañez Oscar Javier , Suarez Marco Javier , Fernandez Eduardo Avendano
Published: July 2023

In surveillance and monitoring systems, the use of mobile vehicles or unmanned aerial vehicles (UAVs), like the drone type, provides advantages in terms of access to the environment with enhanced range, maneuverability, and safety due to the ability to move omnidirectionally to explore, identify, and perform some security tasks. These activities must be performed autonomously by capturing data from the environment; usually, the data present errors and uncertainties that impact the recognition and resolution in the detection and identification of objects. The resolution in the acquisition of data can be improved by integrating data sensor fusion systems to measure the same physical phenomenon from two or more sensors by retrieving information simultaneously. This paper uses the constant turn and rate velocity (CTRV) kinematic model of a drone but includes the angular velocity not considered in previous works as a complementary alternative in Lidar and Radar data sensor fusion retrieved using UAVs and applying the extended Kalman filter (EKF) for the detection of moving targets. The performance of the EKF is evaluated by using a dataset that jointly includes position data captured from a LiDAR and a Radar sensor for an object in movement following a trajectory with sudden changes. Additive white Gaussian noise is then introduced into the data to degrade the data. Then, the root mean square error (RMSE) versus the increase in noise power is evaluated, and the results show an improvement of 0.4 for object detection over other conventional kinematic models that do not consider significant trajectory changes.
Cross-Domain Multi-Prototypes with Contradictory Structure Learning for Semi-Supervised Domain Adaptation Segmentation of Remote Sensing Images
Authors: Gao Kuiliang , Yu Anzhu , You Xiong , Qiu Chunping , Liu Bing , Zhang Fubing
Published: July 2023

Recently, unsupervised domain adaptation (UDA) segmentation of remote sensing images (RSIs) has attracted a lot of attention. However, the performance of such methods still lags far behind that of their supervised counterparts. To this end, this paper focuses on a more practical yet under-investigated problem, semi-supervised domain adaptation (SSDA) segmentation of RSIs, to effectively improve the segmentation results of targeted RSIs with a few labeled samples. First, differently from the existing single-prototype mode, a novel cross-domain multi-prototype constraint is proposed, to deal with large inter-domain discrepancies and intra-domain variations. Specifically, each class is represented as a set of prototypes, so that multiple sets of prototypes corresponding to different classes can better model complex inter-class differences, while different prototypes within the same class can better describe the rich intra-class relations. Meanwhile, the multi-prototypes are calculated and updated jointly using source and target samples, which can effectively promote the utilization and fusion of the feature information in different domains. Second, a contradictory structure learning mechanism is designed to further improve the domain alignment, with an enveloping form. Third, self-supervised learning is adopted, to increase the number of target samples involved in prototype updating and domain adaptation training. Extensive experiments verified the effectiveness of the proposed method for two aspects: (1) Compared with the existing SSDA methods, the proposed method could effectively improve the segmentation performance by at least 7.38%, 4.80%, and 2.33% on the Vaihingen, Potsdam, and Urban datasets, respectively; (2) with only five labeled target samples available, the proposed method could significantly narrow the gap with its supervised counterparts, which was reduced to at least 4.04%, 6.04%, and 2.41% for the three RSIs.
Multi-Copy Relay Node Selection Strategy Based on Reinforcement Learning
Authors: Gao Yang , Zhang Fuquan
Published: July 2023

Delay tolerant networks (DTNs), are characterized by their difficulty in establishing end-to-end paths and and large message propagation delays. To control network overhead costs, reduce message delays, and improve delivery rates in DTNs, it is essential to not only delete messages that have reached their destination but also to more precisely determine appropriate relay nodes. Based on the above goals, this paper constructs a multi-copy relay node selection router algorithm based on Q-lambda reinforcement learning with reference to the idea of community division (QLCR). In community division, if a node has the highestdegree, it is considered the core node, and nodes with similar interests and structural properties are divided into a community. Node degree refers to the number of nodes associated with the node, indicating its importance in the network. Structural similarity determines the distance between nodes. The selection of relay nodes considers node degree, interests, and structural similarity. The Q-lambda reinforcement learning algorithm enables each node to learn from the entire network, setting corresponding reward values based on encountered nodes meeting the specified conditions. Through iterative processes, the node with the most cumulative reward value is chosen as the final relay node. Experimental results demonstrate that the proposed algorithm achieves a high delivery rate while maintaining low network overhead and delay.
Evaluation of Upper Body and Lower Limbs Kinematics through an IMU-Based Medical System: A Comparative Study with the Optoelectronic System
Authors: Cerfoglio Serena , Capodaglio Paolo , Rossi Paolo , Conforti Ilaria , D’Angeli Valentina , Milani Elia , Galli Manuela , Cimolin Veronica
Published: July 2023

In recent years, the use of inertial-based systems has been applied to remote rehabilitation, opening new perspectives for outpatient assessment. In this study, we assessed the accuracy and the concurrent validity of the angular measurements provided by an inertial-based device for rehabilitation with respect to the state-of-the-art system for motion tracking. Data were simultaneously collected with the two systems across a set of exercises for trunk and lower limbs, performed by 21 healthy participants. Additionally, the sensitivity of the inertial measurement unit (IMU)-based system to its malpositioning was assessed. Root mean square error (RMSE) was used to explore the differences in the outputs of the two systems in terms of range of motion (ROM), and their agreement was assessed via Pearson’s correlation coefficient (PCC) and Lin’s concordance correlation coefficient (CCC). The results showed that the IMU-based system was able to assess upper-body and lower-limb kinematics with a mean error in general lower than 5° and that its measurements were moderately biased by its mispositioning. Although the system does not seem to be suitable for analysis requiring a high level of detail, the findings of this study support the application of the device in rehabilitation programs in unsupervised settings, providing reliable data to remotely monitor the progress of the rehabilitation pathway and change in patient’s motor function.
Simulation Analysis of the Dispersion of Typical Marine Pollutants by Fusion of Multiple Processes
Authors: Guo Xueqing , Liu Yi , Zhang Jian-Min , Chen Shengli , Li Sunwei , Hu Zhen-Zhong
Published: July 2023

The rapid development of coastal economies has aggravated the problem of pollution in the coastal water bodies of various countries. Numerous incidents of massive-scale marine life deaths have been reported because of the excessive discharge of industrial and agricultural wastewater. To investigate the diffusion of typical pollutants after discharge, in this study, a multi-process fusion simulation analysis model of pollutants under the action of ocean currents was established based on the concentration analysis method. Furthermore, key technologies involved, such as the parameter value, data selection, and visualization, were investigated. The iterative analysis and programming realization of three independent sub-processes, such as pollutant diffusion and transport, and the drift path and concentration distribution of pollutants after their discharge into the sea, were visualized. The case study revealed that the increase in the concentration of pollutants in the ocean was affected by the diffusion sub-process, and the transport sub-process plays a critical role in the long-distance transport of pollutants. The proposed method can provide technical support for marine environmental risk assessment and dynamic tracking of marine pollutants.
Health Risk and Quality Assessment of Vegetables Cultivated on Soils from a Heavily Polluted Old Mining Area
Authors: Pavlíková Daniela , Zemanová Veronika , Pavlík Milan
Published: July 2023

Three garden vegetables—radish, carrot and lettuce—were cultivated in a pot experiment using two soils from the Příbram area polluted mainly by cadmium (Cd), zinc (Zn), lead (Pb) and chromium (Cr). The soils of the Příbram district, Czech Republic, are heavily polluted as a result of the atmospheric deposition of toxic elements originating from historic lead–silver mining and smelting activities. The results showed that lettuce absorbed the highest amounts of toxic elements (Cd 28 and 30, Cr 12 and 13, Zn 92 and 205 mg·kg−1 DW), except Pb, which was higher in radish (30 and 49 mg·kg−1 DW). Changes in macronutrient contents in edible parts were not found, except for sulfur. A higher total free amino acids (fAAs) accumulation was shown in all vegetables in more contaminated soil, with the highest fAA content being in radish. A group of essential fAAs reached 7–24% of total fAAs in vegetables. The risk to human health was characterized using the target hazard quotient and total hazard index (HI). The cumulative effect of the consumption of vegetables with HI > 1 showed possible non-carcinogenic health effects for lettuce and carrot. HI decreased in the order Cd > Pb > Cr > Zn. The carcinogenic risk of toxic elements decreased in the order Cd > Cr > Pb (0.00054, 0.00026, 0.00003). These values showed a carcinogenic risk from the consumption of lettuce and carrot and confirmed that the adult population of the studied area is at high risk if lettuce and carrot cultivated in this area are consumed daily.
An Overview of the Conventional and Novel Methods Employed for SARS-CoV-2 Neutralizing Antibody Measurement
Authors: Rocha Vinícius Pinto Costa , Quadros Helenita Costa , Fernandes Antônio Márcio Santana , Gonçalves Luana Pereira , Badaró Roberto José da Silva , Soares Milena Botelho Pereira , Machado Bruna Aparecida Souza
Published: July 2023

SARS-CoV-2 is the etiological agent of the coronavirus disease-19 (COVID-19) and is responsible for the pandemic that started in 2020. The virus enters the host cell through the interaction of its spike glycoprotein with the angiotensin converting enzyme-2 (ACE2) on the host cell’s surface. Antibodies present an important role during the infection and pathogenesis due to many reasons, including the neutralization of viruses by binding to different spike epitopes. Therefore, measuring the neutralizing antibody titers in the whole population is important for COVID-19’s epidemiology. Different methods are described in the literature, and some have been used to validate the main vaccines used worldwide. In this review, we discuss the main methods used to quantify neutralizing antibody titers, their advantages and limitations, as well as new approaches to determineACE2/spike blockage by antibodies.
Knowledge, Attitude, and Practice towards Influenza Vaccination among Older Adults in Southern China during the COVID-19 Pandemic
Authors: You Yating , Li Xiaoheng , Chen Binglin , Zou Xuan , Liu Gang , Han Xinxin
Published: July 2023

Influenza is prevalent globally, leading to severe morbidity and mortality. During the pandemic, knowledge, attitude, and practice (KAP) towards influenza virus and vaccination were less investigated among southern Chinese older adults. A cross-sectional study was conducted through the structured questionnaire among community healthcare centers in selected districts in Shenzhen, southern China from September to October 2021. KAP towards influenza virus and vaccination were analyzed. A multivariable logistic regression model was used to identify associated factors. Among 975 participants, 55.6% were reported to have received influenza vaccination ever, and 46.6% had taken influenza vaccination in 2020 during the pandemic. Only one-fifth of participants knew severe comorbidities happen among severe influenza cases. A total of 88.3% thought older adults should have influenza vaccination. COVID-19 vaccination history was associated with receiving influenza vaccination (OR 1.92, 95% CI 1.32–2.80). People with a high-level income had better KAP towards influenza virus and vaccination. COVID-19 vaccination history was associated with the positive actions of influenza vaccination during the pandemic. Efforts should be made to promote the free influenza vaccination program widely and launch health education events on influenza and its vaccination regularly to improve KAP among older adults.
Improving Equity in Urban Immunization in Low- and Middle-Income Countries: A Qualitative Document Review
Authors: Belt Rachel Victoria , Abdullah Shakil , Mounier-Jack Sandra , Sodha Samir V. , Danielson Niklas , Dadari Ibrahim , Olayinka Folake , Ray Arindam , Crocker-Buque Tim
Published: July 2023

Introduction: As the world continues to urbanize, particularly in low- and middle-income countries, understanding the barriers and effective interventions to improve urban immunization equity is critical to achieving both Immunization Agenda 2030 targets and the Sustainable Development Goals. Approximately 25 million children missed one or more doses of the diphtheria, tetanus and pertussis (DTP3) vaccine in 2021 and it is estimated that close to 30% of the world’s children missing the first dose of DTP, known as zero-dose, live in urban and peri-urban settings. Methods: The aim of this research is to improve understanding of urban immunization equity through a qualitative review of mixed method studies, urban immunization strategies and funding proposals across more than 70 urban areas developed between 2016 and 2020, supported by Gavi, the Vaccine Alliance. These research studies and strategies created a body of evidence regarding the barriers to vaccination in urban settings and potential interventions relevant to low- and middle-income countries (LMICs) with a focus on the vaccination of urban poor, populations of concern and residents of informal settlements. Through the document review we identified common challenges to achieving equitable coverage in urban areas and mapped proposed interventions. Results: We identified 70 documents as part of the review and categorized results across (1) social determinants of health, (2) immunization service-delivery barriers and (3) quality of services. Barriers and solutions identified in the documents were categorized in these thematic areas, drawing information from results in more than 21 countries. Conclusion: Populations of concern such as migrants, refugees, residents of informal settlements and the urban poor face barriers to accessing care which include poor availability and quality of service. Example solutions proposed to these challenges include tailored delivery strategies, improved use of digital data collection and child-friendly services. More research is required on the efficacy of the proposed interventions identified and on gender-specific dynamics in urban poor areas affecting equitable immunization coverage.
Classification of values in accounting and reporting
Authors:   Federal State Autonomous Educational Institution of Higher Education “Lobachevsky State University of Nizhny Novgorod”, Nizhny Novgorod, Russia, Druzhilovskaya E.S.
Published: July 2023

For proper accounting and reporting, a clear understanding of the values that can be applied in these areas is necessary. Such an understanding certainly gives the classification of values in accounting and reporting. At the same time, as our studies have shown, today there is no single holistic classification of these values. This article is devoted to the creation of such a classification. As research methods, we used the following: analysis and synthesis, grouping method, comparison, analogy method, logical approach, systematic approach. As a result of the research, we have proposed a comprehensive classification that covers all the most important aspects of values in accounting and reporting (including forty-five classification features), meeting the requirements of modern times. The results presented in this paper will be useful to a wide range of readers interested in various problems of modern accounting and reporting, including the values of accounting objects and reporting elements. The results obtained in this article can also be used in the educational process of higher educational institutions and in the practical work of accounting departments. In addition, the results of this study can be used in the development and improvement of relevant regulatory documents on accounting and reporting.
ANTESEDEN REPURCHASE INTENTION: STUDI EMPIRIS PADA KONSUMEN VITAMIN C SAAT PANDEMI COVID-19 DI JAKARTA
Authors: Briliana Vita , Fialim Guniadi
Published: July 2023

This study aims to examine and analyze how the influence of Brand Trust, Perceived Value and Halal Concern on Brand Preference and Satisfaction and their consequences on Repurchase Intention of consumers of vitamin C products in Jakarta. This research design uses descriptive and causal research by measuring all variables using a Likert scale consisting of 5 points. The sampling technique used was the purposive sampling method which was carried out by distributing questionnaires to 281 respondents. Statistics for data processing with the Structural Equation Model (SEM) analysis method used in this study are SmartPLS version 3.0 and IBM SPSS. The results of this study explain that Brand Trust, Perceived Value and Halal Concern affect Brand Preference and Satisfaction. It was identified that Halal Concern had the most influence on Brand Preference and Satisfaction. Meanwhile, Brand Preference has a higher impact than Satisfaction on Repurchase Intention on vitamin C consumers in Jakarta. The implication of this research is vitamin C producers should register their products to get halal certificate to increase their sales.
INDIVIDUAL PREDISPOSITION AND TAX KNOWLEDGE: GENDER DIFFERENCE ON TAXPAYER COMPLIANCE OF BATIK MSME
Authors: Kusumawardhani Indra , Sirait Afni , Murdianingrum Sri Luna
Published: July 2023

Changes in the business world due to the COVID-19 pandemic have directly affected the Individual predisposition of business people. The government provides several economic stimuli so that the Indonesian economy and adjustments to tax regulations harmonization of tax regulations. Harmonization of tax regulations is expected to help income from the tax sector with taxpayer compliance in paying taxes. The purpose of this study is to analyze the individual predisposiotion of Batik SME’s in the Special Region of Yogyakarta in carrying out tax payment obligations due to the latest legislation harmonization of tax regulations. This research uses the method of purposive sampling with the number of respondents 50 male respondents and 50 womans respondents. Data were processed using WarpPLS 7.0 to aim of examining direct and indirect causal relationships as well as significant and insignificant ones. The results of the study explain that variableIndividual Predispositon male respondents did not affect taxpayer compliance even though the mediation variable Harmonization of Tax Regulations was added, while for woman respondents this had a direct effect. The tax knowledge variable is directly and significantly related to male and woman taxpayer compliance. The mediation variable Harmonization of Tax Regulations has a significant effect on male respondent taxpayer compliance, but the mediation variable provides an insignificant relationship so that this variable fully mediates for woman respondents.
DIVERSIFICATION OF THE ACTIVITIES OF TRADING ENTERPRISES IN THE CONTEXT OF REGIONAL AND SECTORAL DEVELOPMENT OF THE ECONOMY
Authors: Donets Lyubov
Published: July 2023

Based on the constellation of various approaches to the interpretation of the concept of "diversification", the author's understanding of it is formulated, the main elements of the diversification of the activities of a trading enterprise are identified, and the logic of the relationship of objects, processes and results that make up the content of the studied economic category is established, which is visualized in a logical and meaningful a scheme for diversifying the activities of a trading enterprise in the context of regional and sectoral development of the economy. A process-situational approach to the diversification of the activities of a trading enterprise is proposed, the essence of which is the integration of the features of the regional-sectoral economy, as a situational base, and the diversification of the activities of a trading enterprise, as a process. The use of this approach ensures the synergy of the features of the regional-industrial economy and the architectonics of the process of diversifying the activities of a trading enterprise. A scientific and methodological approach to determining the economic feasibility of diversifying the activities of a retail enterprise is proposed, the use of which helps to increase the efficiency of management decisions when planning the diversification of a trading enterprise in the turbulent conditions of the development of a regional sectoral economy. The scientific and practical approach to identifying the level of efficiency of diversification of the types of activities of trading enterprises has been improved, the constitutive basis of which is the calculation of the integral indicator of the effectiveness of diversification of the types of activities of a trading enterprise, including the indicator of return on total resources, the indicator of profitability of total resources, the indicator of profitability of total resources.
A SYSTEM OF FOR SUSTAINABLE DEVELOPMENT ASSESSING OF INDUSTRIAL ENTERPRISES IN THE CONSTRUCTION INDUSTRY
Authors: Bulina Anna
Published: July 2023

The article deals with the topical issue of the development of reporting on the sustainable development of industrial enterprises in the construction industry, which at the moment is voluntary, extending to the choice of tools and evaluation criteria. This approach makes it difficult to get an idea of the sustainable development of enterprises, which determines the relevance of this study. The author offers a criterion assessment of the sustainable development of industrial enterprises of the construction industry, which was based on an empirical study. In the course of the study, an analysis of reports on the sustainable development of industrial enterprises of the construction industry – leaders in sustainable development was carried out, and a list of criteria used by them for reporting on sustainable development was formed, as well as a list of topics significant for reporting allocated by industrial enterprises of the construction industry. Among the general list of topics and criteria, using the scoring system, those that have the greatest impact on the presentation of information about sustainable development were identified – significant criteria. When forming the final list of criteria, a new component of the sustainable development of industrial enterprises of the construction industry, called "digital sustainability", was identified, and criteria for its evaluation were proposed. At the final stage, a final list of topics, criteria and evaluation indicators was formed, which is the basis for a unified system for assessing the sustainable development of industrial enterprises in the construction industry.
One Step to a Cure Outcomes of Experimental Treatments for Non-Hodgkins Lymphomas, A Systematic Review
Authors: Neto Gilberto A. , Cascudo Maria L.
Published: July 2023

Non-Hodgkins lymphomas are malignant lymphatic tumors, mainly affecting B cells. Generally occur in children and young adults with different forms of treatment, however most treatments are accompanied by tumoral relapse.Recently, many researches have been made to identify the best treatment with positive long-term outcomes. In that regard, CAR-T cell treatment has been recognized for its accessibility and effect, it utilizes T cells with chimeric antigen receptors, facilitating cancerous cells detection after non-response to the regular R-CHOP treatment. As data-base 26 research papers were found, with 23 of them being utilized.
Pre-service EFL Teachers’ Knowledge and Beliefs about Developmental Dyslexia: Implications for EFL Teacher Training
Authors: ATAR Cihat , AMİR Alia
Published: July 2023

This study aims to analyse the misconceptions, knowledge, and knowledge gaps of 176 Turkish pre-service English as a foreign language teachers about dyslexia which is a prevalent developmental disorder. The data were collected at eight different universities in Turkiye and analysed by SPSS 25.0 via descriptive statistics and the Kruskal Wallis Test, considering the participants’ scores on the Knowledge and Beliefs about Developmental Dyslexia scale. In addition to studying the knowledge base about dyslexia, the effect of the variables grade and gender was analysed. The results showed that most of the participants had flawed information about dyslexia, and lack of information was common. On the other hand, gender and grade did not have any significant effects. These findings indicate a need for wider awareness and formal education about dyslexia for pre-service English as foreign language teachers to create more inclusive classrooms.
KETERBUKAAN PROSES PERPAJAKAN MELALUI AKSES INFORMASI KEUANGAN
Authors: Setyo Utomo Ananto , Susanti Dyah Ochtorina , Setyawan Fendi
Published: July 2023

Secara umum sudah ada undang-undang yang memberikan perlindungan kepada pihak perbankan selaku pemberi kredit untuk mendapatkan pelunasan pitangnya manakala debitur mengalami wanprestasi, hal itu tertuang dalam Pasal 1131 KUHPerdata yang isinya: “Segala harta kekayaan Debitur, baik yang bergerak maupun yang tidak bergerak, baik yang sekarang ada maupun yang aka nada dikemudian hari menjadi tanggungan/jaminan atas hutang-hutangnyaSalah satu ciri dari UUHT adalah mudah dan pasti dalam pelaksanaan eksekusinya, yang artinya dalam pelaksanaan eksekusi sertipikat hak tanggungan harus dapat dilakukan namun tetap dapat memberikan kepastian hukum bagi pihak yang berkepentingan dalam hal ini adalah penjual lelang, pembeli lelang dan terlelang. Oleh karena itu dalam pelaksanaan eksekusi berdasarkan parate eksekusi harus dapat memberikan kemudahan dan kepastian hukum bagi semua pihak yang berkepentingan.
PENGEMBANGAN USAHA PRODUK UMKM IBU PKK DUSUN SANGKREK
Authors: Fitriyanti Fadia
Published: July 2023

Tujuan Program KKN 073 membantu UMKM Ibu-ibu PKK Dusun Sangkrek, Desa Hargorejo, Kokap, Kabupaten Kulonprogo Daerah Istimewa Yogyakarta yang memiliki produk olahan singkong agar meningkat kualitas produknya dengan cara diversifikasi pangan olahan dan memanfaatkan teknologi yang ada dan menginovasikan produk produknya melalui packaging baru. Dengan demikian produk olahan dapat bervariasi dan pemasaran pangan dapat diperluas keluar daerah dusun Sangklek. Target khusus dan luaran yang dihasilkan dari program KKN ini adalah pengembangan usaha UMKM ibu PKK melalui diversifikasi olahan dan perubahan packaging produk agar tampak lebih menarik apabila diperdagangkan, apalagi pemasaran dapat diperluas dengan menggunakan teknologi. Metode yang akan dipakai untuk mencapai tujuan tersebut yaitu praktek, perantara atau penghubung. ceramah. rencana yang akan dicapai dengan mengadakan pembuatan market place di whats app business serta pelatihannya dan pembuatan packaging baru. Solusi yang ditawarkan adalah pembuatan market place di  whatsapp business disertai dengan pelatihannya serta pembuatan packaging baru.  Hasil pretest dan posttest diperoleh peningkatan pemahaman mengenai pengembangan usaha sebesar (40%), pemahaman mengenai usaha online (40%), pemahaman tentang peran mitra (40%), pemahaman cara pengembangan usaha online (30%), pemahaman mengenai prosedur. usaha online (30%). Sehingga secara  keseluruhan pemahaman peserta terhadap pemahaman pengembangan usaha online, peran mitra untuk pengembangan usaha secara online terjadi kenaikan sebesar 0,5 persen.dapat diterima atau signifikat
Eibar eta Oleta herrietako hikako tratamenduak
Authors: Lopez de Arana Arrieta Inaxio
Published: July 2023

Artikulu honetan bizkaieraren eremuko bi azpieuskalkiren hikako tratamenduei buruzko azterlan txiki bat aurkezten da. Datuak biltzeko, egileak bi herritara jo du: Oleta (Araba) eta Eibar (Gipuzkoa). Bietan ere hiztun bana aukeratu eta elkarrizketatu du, bere inguruko hikako tratamenduaren berri jasotzeko. Argi dago askoz ere hiztun gehiago behar direla, azterlana zientifikoa izango bada. Jakingarri askoak dira, hala ere, hiztun horiek emandako argibideak, nahiz eta begien bistakoa den euskararen tratamendu berezi hori sarritan eskualde berean etxez etxe eta herriz herri aldatzen dela eta bi lagunek emandako datuak ezin direla inola ere ezeren arau izan. Lantxo honek lau atal ditu: galdetegia, erdarazko esaldi batzuen itzulpena, iruzkina eta aditzen paradigma, Oletako eta Eibarko bi hiztunen laguntzarekin ondua.
Zaraitzuera aztertzeko ekarpen berriak 1- Eaurta (hasiera)
Authors: Artola Koldo
Published: July 2023

Zaraitzuera aztertzeko ekarpen berriak izenburu orokorra eman diogun lan honetan, zenbait entregatan garatuz joango garena, nafar Pirinioaren hegoaldean kokatu Zaraitzu ibarreko mintzamoldea, Aezkoa eta Erronkari izeneko ibarren artekoa, aztertzen saiatuko gara, horretarako 1975. urteaz geroztik adin handiko gizon eta emakume batzuengandik bildu ditugun datu ugari samarrak, zein bere testuinguruaren arabera, baliatuko ditugularik. Zaraitzuko euskara Louis-Lucien Bonaparte printze euskaltzaleak egindako mapa zoragarrian ekialdeko behe-nafarreraren esparruan kokaturik agertzen da, horretarako arrazoi nagusienetarik bat, antza, errespetuzko alokutibotasunaren erabilera izaki, ekialdeko euskalkien ezaugarri.
Erroibarko eta Esteribarko oikonimoak (I)
Authors: Orreaga Orreaga
Published: July 2023

Bi artikulu hauen helburua da Esteribar eta Erroibarko etxe-izenen inguruan azterketa bat burutzea. Erroibarren honako urteak hartu dira oinarritzat: 1644, 1726 eta 2001, eta urte hauetan zehar jasandako bilakabidea aztertu da. Metodologia berbera jarraitu da Esteribarren, baina urteak hauek izan dira: 1644, 1677 eta gaurkoak. Artikulu honetan oikonimoen etimologia aztertzen da, eta bide batez hauen sailkapena burutzen da, kontuan izanik zertan dauden oinarriturik etxe-izen hauek: toponimoetan, antroponimoetan edota jentilizioetan. Lan honek bi zati ditu, batean toponimoen zerrendak eta berauen bilakabidea ematen da eta bigarrenean, hauen sailkapena eta etimologia dira aztergai.
On hypocoristic formation in Basque
Authors: Salaberri Patxi
Published: July 2023

This article deals with the different procedures for hypocoristic formation which have existed and still exist in the Basque language. There are three: palatalisation (phonetic symbolism), the use of suffixes (amplification) and reduction or condensation. These procedures, however, are normally combined. For example, the shift Maria → Txariako reveals palatalisation and also contains a suffix; in the shift Domingo → Txomin, both palatalisation and reduction are used; and Josefina → Finatxo is a product of both reduction and a suffix. The use of palatalisation as an expressive resource is an old phenome non, as can be observed from evidence dating from the Middle Ages onwards. Neither is the use of suffixes a modern resource. Some of the suffixes still used today appear in the Aquitaine inscriptions. However, proof of name reduction is, for the most part, modern