bluuebunny/crossref_metadata_2025 huggingface dataset:
Формування конструктивно-планувальних умінь студентів-філологів під час педагогічної практики
Authors: Бакум З. П.
Published: May 2022

У статті обґрунтовується проблема формування професійно-методичних умінь студентів-філологів під час проходження педагогічної практики, серед яких важливе місце посідають конструктивно-планувальні вміння, пов’язані з новаціями у змісті предмета „Українська мова”: теоретичні засади побудови, роль і місце змісту навчання мови в цілісній системі шкільної освіти, складові, рівні його презентації та ін.
Устойчивые сочетания в контексте украинской народной сказки
Authors: Вавринюк Т. І.
Published: May 2022

Досліджено типи фразеологічних одиниць: власне казкові формули, основною функцією яких є композиційно-конструктивна, та стійкі поєднання образно-експресивного характеру - загальнонародні фразеологізми. Проаналізовано стійкі поєднання в контексті української народної казки.
Допомога голодуючим у період Голодомору 1932-1933 рр.: міфи і реальність
Authors: Романець Наталя Радомирівна
Published: May 2022

У статті розглядається допомога голодуючим у період Голодомору 1932-1933 рр.: міфи і реальність.
Особливості реалізації політики розкуркулення на початковому етапі суцільної колективізації (січень-березень 1930 р.)
Authors: Романець Наталя Радомирівна
Published: May 2022

У статті розглядаються особливості реалізації політики розкуркулення на початковому етапі суцільної колективізації (січень-березень 1930 р.)
Показові судові процеси над районним керівництвом як складова антишкідницької операції в аграрному секторі України доби Великого терору 1937-1938 рр.
Authors: Романець Наталя Радомирівна
Published: May 2022

У статті досліджуються показові судові процеси над районними керівниками як складова репресивної кампанії по боротьбі зі шкідництвом в аграрному секторі України під час Великого терору 1937-1938 рр. На основі критичного переосмислення вітчизняної і зарубіжної історіографії, аналізу документів архіву Служби безпеки України, що вперше вводяться до наукового обігу, визначаються особливості, механізми, цілі карально-репресивних заходів влади.
Роль місцевого партійно-державного апарату у здійсненні політики колективізації на Дніпропетровщині
Authors: Романець Наталя Радомирівна , Іваненко Валентин Васильович
Published: May 2022

Досліджено внесок органів влади краю у забезпечення реалізації політики «великого перелому» на селі в кінці 1920 – початку 1930-х рр.
Методичні питання формування усвідомленості знань учнів
Authors: Комаров Володимир Олексійович
Published: May 2022

Розглянуто методичні питання формування усвідомленості знань учнів. Успішність формування усвідомлених знань учнів залежить, зокрема, від відповідних методичних розробок. Останні ж не можуть бути ефективними без розв’язання цілої низки проблем на методологічному рівні.
Utilization of Iron Scrap for Palm Oil Mill Effluent Treatment by Fenton and Foto-Fenton Processes
Authors: Sari Diana Novita , Amelia Dea , Ramadhon Muhammad David , Tiandho Yuant
Published: May 2022

The increase in the amount of palm oil production impacts increasing the total liquid waste from the processing of palm oil. Palm oil mill effluent (POME) has high chemical oxygen demand (COD) and biochemical oxygen demand (BOD) parameters that can cause environmental pollution. This study processed POME using the Fenton mechanism using reagents derived from scrap iron. The Fenton mechanism is one of the advanced oxidation process technology (AOPs) in wastewater treatment. To improve the performance of the Fenton mechanism, the researchers integrated it with UV-rays in the photo-Fenton mechanism scheme. Fenton and photo-Fenton processes effectively reduce the pH, BOD, and COD of POME. The COD removal efficiency was 99.91%, while the BOD removal efficiency was 99.93%. The more FeSO4 added to the wastewater, the more significant the reduction of BOD and COD in the Fenton and photo-Fenton processes. Also, photo-Fenton is more effective than the Fenton process to reduce BOD and COD in the POME.Keywords: POME; Fenton; Photo-Fenton; Scrap ironABSTRAKPemanfaatan Besi Bekas untuk Pengolahan Limbah Cair Industri Kelapa Sawit Melalui Proses Fenton dan Foto-FentonMeningkatnya jumlah produksi kelapa sawit, berdampak pada peningkatan total limbah cair dari hasil pengolahan kelapa sawit. Limbah cair industri kelapa sawit atau Palm Oil Mill Effluent (POME) memiliki nilai parameter chemical oxygen demand (COD) dan biochemical oxygen demand (BOD) yang tinggi sehingga dapat menyebabkan pencemaran lingkungan. Di dalam penelitian ini, dilakukan pengolahan POME menggunakan mekanisme Fenton menggunakan reagen yang berasal dari besi bekas. Mekanisme Fenton adalah salah satu pengembangan dari teknologi proses oksidasi maju (AOPs) dalam pengolahan air limbah.  Untuk meningkatkan performa dari mekanisme Fenton, peneliti mengintegrasikan system tersebut dengan sinar-UV dalam skema mekanisme foto-Fenton. Proses Fenton dan foto-Fenton sangat efektif dalam menurunkan pH, BOD dan COD dari POME. Efisiensi penyisihan COD mencapai 99,91%, sedangkan efisiensi penyisihan BOD mencapai 99,93%. Semakin banyak FeSO4 yang ditambahkan ke dalam air limbah maka semakin besar reduksi BOD dan COD dalam proses Fenton dan foto-Fenton. Selain itu, foto-Fenton lebih efektif dibandingkan dengan proses Fenton dalam mereduksi BOD dan COD dalam POMEKata kunci : POME; Fenton; foto-Fenton; besi bekas
Secondary Metabolites and Potential Antioxidants of Nutmeg (Myristica fragrans Houtt) Mace from West Java
Authors: Erza Rahmatul Kartini , Karmanah Karmanah , Nurlela Nurlela
Published: May 2022

Nutmeg mace is a mesh-shaped seed coat that is bright red when the fruit is ripe and yellowish-white when immature, which generally contains secondary metabolites such as flavonoids and phenolics. This study aimed to examine the content of flavonoids and phenolics, the antioxidant activity of ethanol extract of the nutmeg (Myristica fragrans Houtt) mace based on three regions in West Java i.e. Sukabumi, Cianjur, and Bogor District with age differences. Total phenolic content was measured spectrophotometrically using the Folin Ciocalteau reagent. The total flavonoid content was quantitatively measured using the AlCl3 colorimetric method. Antioxidant activity was tested by measuring the IC50 using the 2,2-diphenyl-1-picryl hydrazyl (DPPH) method. The highest phenolic content was found in young nutmeg from Sukabumi Regency (76.40 mgTAE/g). The highest flavonoid content was found in old age mace nutmeg from Bogor Regency (20.33 mgQE/g). Nutmeg mace has the potential as a natural antioxidant because it can reduce free radicals in DPPH with the lowest IC50 of 153.5 mg/L in old mace from Cianjur District.Keywords: Myristica fragrans Houtt; Mace; Phenolic; Flavonoid; Antioxidant ActivityABSTRAKKandungan Metabolit Sekunder Dan Potensi Antioksidan Fuli Buah Pala (Myristica Fragrans Houtt) Dari Jawa BaratFuli pala adalah selubung biji berbentuk jala berwarna merah terang ketika buah sudah matang dan berwarna putih kekuningan ketika belum matang, yang  umumnya mengandung senyawa metabolit sekunder diantaranya flavonoid dan fenolik. Tujuan penelitian ini  untuk menguji kandungan senyawa flavonoid, fenolik dan aktivitas antioksidan ekstrak etanol fuli pala (Myristica fragrans Houtt) berdasarkan tiga wilayah yaitu Kabupaten Sukabumi, Kabupaten Cianjur dan Kabupaten Bogor dengan perbedaan usia. Kadar total fenolik diukur spektrofotometri menggunakan reagen Folin Ciocalteau, Kadar total flavonoid secara kuantitatif dengan metode kolorimetri AlCl3. Aktivitas antioksidan diuji dengan mengukur nilai IC50 dengan metode 2,2- difenil-1-pikril hidrazil (DPPH). Kadar fenolik tertinggi didapatkan pada pala usia muda dari Kabupaten Sukabumi dengan kadar sebesar 76,40 mgTAE/g. Kadar flavonoid tertinggi didapat pada fuli pala usia tua di Kabupaten Bogor dengan kadar sebesar 20,33 mgQE/g. Fuli buah pala berpotensi sebagai antioksidan alami karena mampu meredam radikal bebas pada DPPH dengan IC50 terendah sebesar 153,5 mg/L yang diperoleh dari fuli usia tua dari Kabupaten Cianjur.Kata kunci: Myristica fragrans Houtt; Fuli; Fenolik; Flavonoid; Aktivitas Antioksidan
Descripción de nuevas especies de marginelas
(Mollusca: Neogastropoda: Marginellidae) de las
islas Canarias, con aclaraciones sobre otros taxones
citados previamente
Authors: Espinosa José , Ortega Jesús , Moro Leopoldo
Published: May 2022

N: Se describen cinco especies nuevas de moluscos marinos de la
familia Marginellidae, cuatro del género Volvarina y una del género Prunum,
a partir de ejemplares colectados en las islas de Lanzarote, Fuerteventura, Tenerife y Gran Canaria: de cuatro de ellas se aportan datos de los animales
vivos; en dos ellas se decriben la rádula y el órgano de Leiblen. Adicionalmente, se discuten algunas especies de la familia citadas previamente en las
islas, y se repudian V. monilis, V. olivaeformis, V. ampelusica y V. deliciosa
Sweet Sap from Palms, a Source of Beverages, Alcohol,
Vinegar, Syrup, and Sugar
Authors: Francisco Ortega Javier , Zona Scott
Published: May 2022

The use of palms as a source of sweet sap is ancient and widespread throughout the palm-growing regions of Africa, Asia and the Americas. Sweet sap is consumed fresh, processed into syrup or sugar, or fermented
into alcohol or vinegar. We review 40 species of palms and their tapping methods, which may be either destructive or nondestructive. Nondestructive
exploitation, as with Phoenix canariensis, can provide a sustainable harvest
Nuevas adiciones y citas de interés para la flora autóctona y alóctona de las islas Canarias
Authors: Santos Guerra Arnoldo , Reyes Betancort Jorge Alfredo
Published: May 2022

One new species (Linaria simplex) is reported for the native flora of the Canary Islands as well as 16 species are new to the aloctonous flora of Tenerife, Gomera or La Palma islands. Among others Tetraclinis articulata is confirmed as subspotaneous in the flora of Gran Canaria island. Keywords: Native, aloctonous, Canarian flora, Linaria.
The effects of Membrane Lipid Replacement with NTFactor® Lipids on increasing the bioavailability of three test nutrients
Authors: Settineri Robert , Ji Jin , Shields Zenaida P. , Nicolson Garth L.
Published: May 2022

Introduction: Previous studies indicated that lipids and nanostructured materials may improve the uptake of nutrients with moderate bioabsorption properties.  Objectives: This study evaluated the effects of Membrane Lipid Replacement with NTFactor® Lipids (NTFL) on bioabsorption of three poorly to moderately absorbed nutrients (quercetin, curcumin and coenzyme Q10) utilizing the Caco-2 epithelial cell permeability model. Methods: Transfer across a Caco-2 epithelial cell layer has become a reference standard in the pharmaceutical and nutraceutical industries for in vitro prediction of in vivo human intestinal absorption and bioavailability of orally administered substances. The degree of bioabsorption of the test materials was assessed by monitoring the concentrations of the test materials on each side of the Caco-2 monolayers by liquid chromatography and mass spectroscopy (LCMS/MS analysis).Results: When NTFL was added to each of the three test nutrients, there was increased absorption and transfer across a Caco-2 cell layer in a dose-dependent manner for the three nutrients. When compared individually, CoQ10 with NTFL showed the most significant increase in absorption (2.01-times more compared to controls without NTFL, p=0.0011) at a concentration of NTFL of 10 mg/mL. NTFL also increased absorption and transfer across a Caco-2 cell layer of the other test nutrients, but these results did not achieve the same level of significance.  Discussion: A variety of Oral membrane lipid replacement supplements with NTFL, such as various vitamins, minerals and nutrients, have been designed to reduce fatigue, improve health conditions, and protect cellular and especially mitochondrial membranes from damage. Here we used NTFL to demonstrate improvements in absorption and bioavailability of three nutrients. Conclusion: Using the Caco-2 bioabsorption and bioavailability in vitro model we found that NTFL could enhance absorption, bioavailability and uptake of nutrients while providing its own clinically demonstrated health benefits. Keywords: Phospholipids, Membrane Lipid Replacement, CoQ10, curcumin, quercetin, bioavailability, absorption, permeability, Caco2, bio-uptake, bioabsorption, glycerolphospholipids, intestinal absorption
Gornjostubički slučaj Ciglar i Žukina u kontekstu seljačke pobune zbog žigosanja stoke 1920.
godine
Authors: Vuković Saša
Published: May 2022

U ovom članku autor se bavi uzrocima i posljedicama napada na gornjostubičke državne službenike i trgovce Ciglar i Žukina za trajanja seljačkih nemira zbog žigosanja stoke 1920. godine. U tu svrhu spomenuta je pobuna, s naglaskom na područje kotara Donja Stubica, iskorištena kao kontekst opisivanih zbivanja, odnosno pomoćno sredstvo u objašnjavanju opisanih postupaka. Uporabom arhivskog materijala, sastavljenog za potrebe žalbe oštećenih zbog izostanka dodjele obećane odštete 1923. godine, te povlačenjem paralela sa sličnim situacijama u drugim mjestima sjeverozapadne Hrvatske, autor dolazi do zaključka o višeslojnosti uzroka napada na kućanstva Ciglar i Žukina, sastavljena od općeg nezadovoljstva društvenom situacijom te od akumulirane netrpeljivosti prema lokalnim predstavnicima nove vlasti. Također, naglasak je stavljen i na nepodudaranje između samoreprezentacije oštećenika u pismima beogradskim organima vlasti i stvarne situacije na području njihovog djelovanja.
Krležin kajkavski trolik/trolist/troslik (model i varijacije u konstrukciji lika kajkavca: Joža, Petrica, Valent)
Authors: Kovač Emilija
Published: May 2022

U kompleksu dugovremene Krležine zaokupljenosti kajkavštinom kao jezikom i njome upisanim svjetonazorom, rad analizira mentalitetne i konstrukcijske momente (označenost lika jezikom) u oblikovanju trojice osebujnih kajkavaca: Jože Podravca – Povratak Filipa Latinovicza, 1932., Petrice Kerempuha – Balade Petrice Kerempuha, 1936. te Valenta Žganca – Na rubu pameti, 1938. Obiman raspoloživ materijal sažimamo na diskurs navedenih likova (i diskurz o njima). Likove razmatramo kao samostalne i samosvojne konstrukte, a njihovo pojavljivanje u vremenskoj sukcesiji i njihovo usložnjavanje otvara mogućnost pristupa kao varijacijama srodnog koncepta.
Comparison of screw-home movement between patients with knee osteoarthritis and normal adults
Authors: Jeon Jeongwoo , Lhee Sang Hoon , Chong Suri , Lee Dongyeop , Yu Jaeho , Kim Jinseop , Kim Seong-Gil , Hong Jiheon
Published: May 2022

BACKGROUND: Tibial rotation accompanying sagittal movement contains the phenomenon of screw-home movement (SHM) of the knee, which plays an important role in knee stability during extension. OBJECTIVE: This study aimed to investigate the change of SHM in patients with knee osteoarthritis (OA). METHODS: Thirty-one sex-matched patients with knee OA and 31 normal subjects were recruited. The total tibial rotation was obtained during knee sagittal movement (extension and flexion) using an inertial measurement unit. The acquired angle of tibial rotation was divided into eight periods. The total tibial rotation and the variation of each period were compared between the OA and control groups. The difference in tibial rotation according to Kellgren-Lawrence (KL) grade was compared. RESULTS: The total tibial rotation of the OA group decreased compared with the control group during knee extension and flexion (P< 0.001). Variations of tibial rotation were significantly different between groups in all periods (P< 0.001) except for knee extension at 70∘ to 45∘ (P= 0.081). There was no significant difference in tibial rotations among the KA grades of OA patients. CONCLUSION: We found a reduction in the total tibial rotation and loss of the SHM in the unloaded OA knee. It could be predicted that reduced SHM appeared early in knee OA.
Quality of life in working populations with and without musculoskeletal pain in Saudi Arabia
Authors: Algarni Fahad Saad Homed
Published: May 2022

BACKGROUND: Musculoskeletal (MSK) pain can negatively affect work life and quality of life (QoL). OBJECTIVE: This study characterizes the QoL of workers in Saudi Arabia and compares it between adults of working age with and without MSK pain. METHODS: This is a descriptive cross-sectional study. The Short Form-36 (SF-36) instrument was used to measure eight domains that describe QoL among workers with and without MSK pain. Descriptive statistics and parametric tests enabled comparisons between the two sets of workers. RESULTS: A total of 2042 workers participated in the study. The majority of them had experienced MSK pain during the last 12 months. In addition, the results for most SF-36 domains varied significantly across age and gender groups. Workers who lacked MSK pain over the last 12 months reported higher means for all SF-36 domains, with the exception of the physical function domains. CONCLUSION: This study found that the majority of workers experience MSK pain. In all bodily regions, neck and back pain are the most frequently reported areas of discomfort for these employees. Workers without MSK pain experience better QoL. This observation suggests the need for managers to pay closer attention to workers with MSK pain, as these employees experience significantly lower QoL. To prevent or reduce MSK pain, workers should undergo routine medical examination and early intervention for MSK pain. These preventative measures can help to increase workers’ QoL.
Effects of Kinesio tape on pain and edema following surgical extraction of the third molar: A meta-analysis and systematic review
Authors: Qi Jing , Yue Haiquan , Liu E. , Chen Guang , Liu Yuting , Chen Jiahui
Published: May 2022

BACKGROUND: Kinesio tape (KT) has been in extensive use for the rehabilitation of injuries related to sports, however, only a handful of studies have focused on the efficacy of KT following extraction of a third molar tooth. OBJECTIVE: The study aims to assess whether pain and edema following surgical extraction of the third molar can be reduced by KT. METHOD: This research was carried out following the principles of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Web of Science, Embase, PubMed, The Cochrane Library, CNKI, VIP, and WanFang Data databases were searched for trials published from their inception to eighth October 2021. They included published randomized controlled trials in Chinese or English languages. The methodological quality of the included studies was assessed using the Physiotherapy Evidence Database scale. Mean differences (MDs) with 95% confidence intervals (CIs) were used for the analysis of continuous data. The heterogeneity was measured using the I2 statistics. Then, Revman 5.4 software was employed for performing the meta-analysis. RESULTS: Eight studies comprising 453 participants in total were included. In comparison to the no kinesio tape group, KT did not furnish improved results on mouth opening ([MD = 0.36, 95% CI (-0.67, 1.40), p= 0.49]), and swelling ([MD =-1.24, 95% CI (-3.43, 0.95), p= 0.79]). However, KT manifested a reduction in operation time ([MD =-1.00, 95% CI (-1.93, -0.07), P= 0.04]), edema ([MD =-0.53, 95% CI (-0.88, -0.19), P= 0.003]), and pain intensity ([MD =-1.29, 95% CI (-1.86, -0.73), P< 0.00001]), favouring the kinesio tape group. Overall, the size of the effect was found in the small to moderate range. CONCLUSION: Despite the fact that KT can reduce pain and has been shown to have positive effects in several studies, there is no convincing evidence that it can reduce the swelling after surgical extraction of the third molar.
Between formality and informality: A critical study of the integration of drones within the Neuchâtel police force12
Authors: Pedrozo Silvana , Klauser Francisco
Published: May 2022

The use of police drones in Switzerland has significantly increased since the early 2000s. However, Swiss citizens remain largely uninformed about the multifold uses of drones by the police. Whilst many public institutions today advocate more transparent decision-making processes in security matters, this paper demonstrates that the acquisition of police drone systems results from a set of interdependent socio-technical mediations that are inherently opaque, and that bring together both formal and informal mechanisms. Drawing upon qualitative interviews and observational research conducted with Neuchâtel police (Switzerland), this analysis highlights the importance of the practical and relational mechanisms that interlink various public and private actors with the objects in question. This raises a series of informality issues surrounding the acquisition of police technologies more generally.
A modularly tailored commuter ferry platform
Authors: Cheemakurthy Harsha , Garme Karl
Published: May 2022

Background: Among the challenges for implementation of Waterborne public transportation (WPT) are the difficulties in procuring efficient ferries tailored towards local requirements. Fundamental questions on the ferry’s environmental impact, speed and procurement costs linger in the public transport (PTP) mind. Objective: In this paper, a methodology for adopting a platform architecture for ferries is illustrated by a modular design approach. Methods: For this, WPT operational profiles are categorized by three route types in a structure for operational requirements including sustainability performance. Generic parameters for size and speed of WPT ferries are defined. Using these parameters as a skeletal structure, a modular commuter ferry concept is proposed as a set of basic modules. As a combination of these functionally independent modules, a ferry can be tailored to fit the operational requirements. Results: The paper proposes standard sizes for waterborne commuter craft and shows that ferries are compatible with land-based public transport in terms of energy efficiency and speed. Suitable speed ranges for mono hulls and catamarans are investigated and the idea of modular design for rational procurement is explored and illustrated for the three type routes. Conclusions: The proposed concepts can make WPT more attractive for PTPs as a sustainable option to complement the existing network.
Data-Driven Analyses of Longitudinal Hippocampal Imaging Trajectories: Discrimination and Biomarker Prediction of Change Classes
Authors: Drouin Shannon M. ,   for the Alzheimer’s Disease Neuroimaging Initiative, McFall G. Peggy , Potvin Olivier , Bellec Pierre , Masellis Mario , Duchesne Simon , Dixon Roger A.
Published: May 2022

Background: Hippocampal atrophy is a well-known biomarker of neurodegeneration, such as that observed in Alzheimer’s disease (AD). Although distributions of hippocampal volume trajectories for asymptomatic individuals often reveal substantial heterogeneity, it is unclear whether interpretable trajectory classes can be objectively detected and used for prediction analyses. Objective: To detect and predict hippocampal trajectory classes in a computationally competitive context using established AD-related risk factors/biomarkers. Methods: We used biomarker/risk factor and longitudinal MRI data in asymptomatic adults from the AD Neuroimaging Initiative (n = 351; Mean = 75 years; 48.7% female). First, we applied latent class growth analyses to left (LHC) and right (RHC) hippocampal trajectory distributions to identify distinct classes. Second, using random forest analyses, we tested 38 multi-modal biomarkers/risk factors for their relative importance in discriminating the lower (potentially elevated atrophy risk) from the higher (potentially reduced risk) class. Results: For both LHC and RHC trajectory distribution analyses, we observed three distinct trajectory classes. Three biomarkers/risk factors predicted membership in LHC and RHC lower classes: male sex, higher education, and lower plasma Aβ1–42. Four additional factors selectively predicted membership in the lower LHC class: lower plasma tau and Aβ1–40, higher depressive symptomology, and lower body mass index. Conclusion: Data-driven analyses of LHC and RHC trajectories detected three classes underlying the heterogeneous distributions. Machine learning analyses determined three common and four unique biomarkers/risk factors discriminating the higher and lower LHC/RHC classes. Our sequential analytic approach produced evidence that the dynamics of preclinical hippocampal trajectories can be predicted by AD-related biomarkers/risk factors from multiple modalities.
Nocturnal Hypoxia and Sleep Fragmentation May Drive Neurodegenerative Processes: The Compared Effects of Obstructive Sleep Apnea Syndrome and Periodic Limb Movement Disorder on Alzheimer’s Disease Biomarkers
Authors: Fernandes Mariana , Chiaravalloti Agostino , Manfredi Natalia , Placidi Fabio , Nuccetelli Marzia , Izzi Francesca , Camedda Riccardo , Bernardini Sergio , Schillaci Orazio , Mercuri Nicola Biagio , Liguori Claudio
Published: May 2022

Background: Sleep disorders may cause dysregulation in cerebral glucose metabolism and synaptic functions, as well as alterations in cerebrospinal fluid (CSF) biomarker levels. Objective: This study aimed at measuring sleep, CSF Alzheimer’s disease (AD) biomarkers, and cerebral glucose consumption in patients with obstructive sleep apnea syndrome (OSAS) and patients with periodic limb movement disorder (PLMD), compared to controls. Methods: OSAS and PLMD patients underwent 18F-fluoro-2-deoxy-D-glucose positron emission tomography (18F-FDG PET), polysomnographic monitoring, and lumbar puncture to quantify CSF levels of amyloid-β42 (Aβ42), total tau, and phosphorylated tau. All patients were compared to controls, who were not affected by sleep or neurodegenerative disorders. Results: Twenty OSAS patients, 12 PLMD patients, and 15 controls were included. Sleep quality and sleep structure were altered in both OSAS and PLMD patients when compared to controls. OSAS and PLMD patients showed lower CSF Aβ42 levels than controls. OSAS patients showed a significant increase in glucose uptake in a wide cluster of temporal-frontal areas and cerebellum, as well as a reduced glucose consumption in temporal-parietal regions compared to controls. PLMD patients showed increased brain glucose consumption in the left parahippocampal gyrus and left caudate than controls. Conclusion: Sleep dysregulation and nocturnal hypoxia present in OSAS patients, more than sleep fragmentation in PLMD patients, were associated with the alteration in CSF and 18F-FDG PET AD biomarkers, namely reduction of CSF Aβ42 levels and cerebral glucose metabolism dysregulation mainly in temporal areas, thus highlighting the possible role of sleep disorders in driving neurodegenerative processes typical of AD pathology.
Cattle Encephalon Glycoside and Ignotin Ameliorate Palmitoylation of PSD-95 and Enhance Expression of Synaptic Proteins in the Frontal Cortex of a APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease
Authors: Zhang Yinghan , Hu Yazhuo , Han Zhitao , Geng Yan , Xia Zheng , Zhou Yongsheng , Wang Zhenfu , Wang Yuanyuan , Kong Eryan , Wang Xiaoning , Jia Jianjun , Zhang Honghong
Published: May 2022

Background: Synaptic abnormalities in synaptic proteins are the initial hallmarks of Alzheimer’s disease (AD). The higher level of palmitoylation of synaptic proteins was closely associated with amyloid-β (Aβ) in AD. Cattle encephalon glycoside and ignotin (CEGI) have been shown to act as multitarget neurotrophic agents in APPswe/PS1dE9 (APP/PS1) transgenic AD mice. However, it is not clear whether CEGI can influence Aβ deposition or whether it does so by the regulation of protein palmitoylation and expression of synaptic proteins in transgenic AD mice. Objective: In this study, we investigated the roles of CEGI in modulating postsynaptic density protein 95 (PSD-95) palmitoylation, Aβ pathologies, and expression of synaptic-associated proteins in APP/PS1 mice. Methods: Five-month-old APP/PS1 mice were treated intraperitoneally with 6.6 mL/kg of CEGI for 6 weeks. At the end of the treatment period, APP/PS1 mice were subjected to Morris water maze to test their cognitive functions. Acyl-biotinyl exchange (ABE) for PSD-95 palmitoylation, immunofluorescent staining for expression of PSD-95, N-methyl-D-aspartic acid receptor subunit 2B (NR2B), and synaptotagmin 1 (SYT1) were assessed in mouse brain sections. Results: CEGI treatment in APP/PS1 mice significantly reduced Aβ deposition, relieved memory deficits, and decreased PSD-95 palmitoylation while markedly increasing the expression of PSD-95, NR2B, and SYT1 in the frontal cortex. There was a significant correlation between Aβ expression and PSD-95 palmitoylation in APP/PS1 mice. Conclusion: Our findings demonstrate that CEGI improved AD-like neuropathology, possibly by inhibiting PSD-95 palmitoylation, improving learning memory, and enhancing expression of synaptic-associated proteins, representing a potential therapy for AD treatment.
Gut Microbiota and Subjective Memory Complaints in Older Women
Authors: Wu Fen , Davey Samuel , Clendenen Tess V. , Koenig Karen L. , Afanasyeva Yelena , Zhou Boyan , Bedi Sukhleen , Li Huilin , Zeleniuch-Jacquotte Anne , Chen Yu
Published: May 2022

Background: Epidemiological studies that investigate alterations in gut microbial composition associated with cognitive dysfunction are limited. Objective: To examine the association between the gut microbiota and subjective memory complaints (SMCs), a self-reported, validated indicator of cognitive dysfunction. Methods: In this cross-sectional study of 95 older women selected from the New York University Women’s Health Study (NYUWHS), we characterized the gut microbial composition using 16S rRNA gene sequencing. We estimated odds ratio (OR) from beta regression which approximates the ratio of mean relative abundances of individual bacterial taxon from phylum to genus levels by binary (2+ versus < 2) and continuous SMCs. Results: Women reporting 2 or more SMCs had higher relative abundances of genus Holdemania and family Desulfovibrionaceae compared with those reporting one or no complaint. Compared with women with < 2 SMCs, the relative abundances of Holdemania and family Desulfovibrionaceae were 2.09 times (OR: 2.09, 95% confidence interval [CI]: 1.38–3.17) and 2.10 times (OR: 2.10, 95% CI: 1.43–3.09) higher in women with 2+ SMCs, respectively (false discovery rate (FDR)-adjusted p = 0.038 and 0.010, respectively). A dose-response association was observed for genus Sutterella and family Desulfovibrionaceae. Every one-unit increase in SMCs was associated with 25% and 27% higher relative abundances of Sutterella (OR: 1.25; 95% CI: 1.11–1.40) and Desulfovibrionaceae (OR: 1.27; 95% CI: 1.13–1.42), respectively (FDR-adjusted p = 0.018 and 0.006, respectively). Conclusion: Our findings support an association between alterations in the gut bacterial composition and cognitive dysfunction.
Education and Literacy as Risk Factors of Dementia after Stroke and Transient Ischemic Attack: NEDICES Study
Authors: Contador Israel , Alzola Patricia , Bermejo-Pareja Félix , del Ser Teodoro , Llamas-Velasco Sara , Fernández-Calvo Bernardino , Benito-León Julián
Published: May 2022

Background: A protective effect of education on cognitive decline after stroke has been claimed, but evidence from prospective population-based cohorts is very limited. The differential role of literacy and education on dementia after stroke remains unexplored. Objective: This research addresses the role of education and literacy in dementia incidence after stroke and transient ischemic attack (TIA). Methods: 131 participants with stroke or TIA were identified within the population-based NEDICES study (N = 5,278 persons). Participants were fully assessed at baseline (1994–1995) and incident dementia diagnosis was made by expert neurologists (DSM-IV criteria) after a mean follow-up of 3.4 years. Adjusted Cox regression analyses were applied to test the association between education, literacy, and dementia risk. Results: Within the 131 subjects with stroke or TIA, 19 (14%) developed dementia at follow-up. The Cox’s regression model (age and sex adjusted) showed that low education (HR = 3.48, 95% CI = 1.28, 9.42, p = 0.014) and literacy (HR = 3.16, 95% CI = 1.08, 9.22, p = 0.035) were significantly associated with a higher dementia risk. Low education was also associated with dementia when main confounders (i.e., cognitive/functional performance) were considered in the Cox’s model. However, after including stroke recurrence, only low/null literacy (versus education) remained as significant predictor of dementia. Finally, low/null literacy showed an effect over-and-above education on dementia risk when both factors were introduced in the adjusted Cox’s regression. Conclusion: These findings underline the importance of literacy to estimate cognitive decline after stroke in low-educated populations.
The whole field temperature rise calculation of oil-immersed power transformer based on thermal network method
Authors: Ai Mengmeng , Shan Yi
Published: May 2022

With the rapid development of UHV power transmission and transformation project in our country, the gradually increasing electromagnetic capacity and electromagnetic loads of power transformers causes serious heating of the transformers. Therefore, it is particularly important to accurately calculate its temperature rise. Based on field-circuit coupling method, this paper took a 240000 KVA, 330 KV power transformer as the research object to calculate the whole temperature rise and heat transfer characteristics. Firstly, the average velocity of fluid was gotten by three-dimensional flow field of transformer which is calculated by establishing thermal network model of the transformer, phase winding and related structures. And then substitute it into thermal network model. The whole average temperature and temperature rise was gotten by using first law of thermodinamics and after the iteration. And according to the temperature rise test, this paper comprised and analyzed the computed results of thermal network and numerical analysis. Results showed that the error of the thermal network model was within the scope of the permit, and it was simple and quick. The method can provide basis for the future heat transfer research and temperature rise prediction of transformer.
A new dynamic displacement prediction method for contactors with constant air gap
Authors: Wang Gongrun , Dong Enyuan , Wang Yongxing , Yin Sheng , Zhang Liyan , Qin Taotao
Published: May 2022

In order to improve the dynamic characteristics of the contactor, this paper proposes a new dynamic displacement prediction method for contactors with constant air gap. The dynamic displacement process can be predicted by observing the flux linkage produced by the permanent magnet. The equivalent magnetic circuit model of electromagnetic force driving actuator (EMFA) is established. The formulas of dynamic flux linkage, displacement and current are deduced, and the displacement prediction of the contactor is completed. The curved surfaces of driving force, flux linkage, displacement and current are established by finite element method. The movement process of the contactor is dynamically simulated by interpolation method. Finally, an EMFA-driven contactor is used for the experiment. Experimental results show that the new dynamic displacement prediction method is suitable for contactors with constant air gap. On the basis of sensorless control, bounce time of the contact can be effectively reduced by adjusting the PWM duty cycle and the corresponding displacement control parameters. The research in this article can be used to guide the design of future controllers. And the simulation results are consistent with the experimental results. The experiment verifies the effectiveness of the new dynamic displacement prediction method.
Effect of ultrasonic non-thermal sterilization on the volatile components of pumpkin juice
Authors: Suo Guanwen , Zhou Chunli , Su Wei , Hu Xueyan
Published: May 2022

The objective of this study was to investigate the effects of ultrasonic treatment on the aroma profile of pumpkin juice. Samples were treated according to the experimental design, with a numerically controlled ultrasonic instrument at an ultrasound frequency of 45 kHz under various conditions (treatment times of 10, 20, and 30 min, sample temperature of 25(± 2)∘C, and powers of 180, 240, and 300 W). The aromatic profiles of pumpkin juice showed that a total of 52 volatile components were detected in the 10 groups of pumpkin juices, including 16 alcohols, 11 alkane olefins, 6 aldehydes, 4 ketones, 4 esters, and 11 others. Alcohol compounds had the highest content among all volatile compounds; the most abundant were 1-Octen-3-ol, (E, Z)-3, 6-Nonadien-1-ol, 1-hexanol, and (Z) -3-Nonen-1-ol. Compared to the untreated samples of juices, ultrasonic treatment leads to the formation of new compounds or the disappearance of compounds found in the untreated samples. The findings presented in this study provide a deeper understanding of the application of ultrasound to enhance the volatile components of pumpkin juice.
Small sample and efficient crop pest recognition method based on transfer learning and data transformation
Authors: Wei Qingfeng , Li Huan , Luo Changshou , Yu Jun , Zheng Yaming , Wang Furong , Zhang Bao
Published: May 2022

In order to solve the problem of long training time and large samples required by traditional image recognition model, a method of crop pest recognition based on transfer learning and data conversion was proposed. It takes CNN models such as Inception V3, VGG16, ResNet as the backbone structure. And the transfer learning was used to improve the model effect. The original picture data was expanded through the transformation of flip, rotation, scale, crop, translation and shading. Based on the data of 11 common pests such as white grub, east asian locust and whitefly etc., the model training and recognition was carried out. The result shows that, the accuracy of transfer learning model is higher than that of non-transfer learning model. The Inception V3 model performs well of all, the recognition accuracy is more than 98.94%. Through the analysis of cross entropy and confusion matrix, data transformation is helpful to improve the accuracy of the model with small sample.
Nursing Approaches and Perceived Quality of Life in Advanced Stage Huntington’s Disease Patients
Authors: Engels Josine , van Duijn Erik
Published: May 2022

Background: Long-term Huntington’s disease (HD) care is offered in specialized inpatient nursing home units with a focus on individually perceived quality of life (QoL). This is shaped in daily care and interaction, which is often abstract and intangible. Furthermore, different perspectives are involved and may vary. Objective: To explore and describe perceived QoL of HD patients from three perspectives: manifest HD patients, family members, and nursing staff. Methods: 36 patients, 11 family members, and 30 nurses participated in this qualitative study by means of individual interviews and systematic qualitative observations on three units. Results: Preservation of identity and autonomy is important for patients. Patients struggle with increasing dependence, and try to cope with the impact, uncertainty, and progressive nature of the disease. All participants emphasize the focus on “being human, not just a patient”. Both patients and family members mention the difficulty of dealing with altered behavior and loss of control. Patients are reliant on a relational approach, and an attitude of unconditional acceptance, trust, and understanding support by the nurses. Nursing staff help patients to focus on preserved abilities, and to continue to engage in personalized preferred social activities. Specific qualifications of the nurses were of major influence on QoL for HD patients. Conclusion: This study shows, from the patient as well as family member and nursing staff perspectives, that caring for HD patients requires specific knowledge and skills. Particular nursing approaches and attitude and qualifications of the nursing staff in residential HD care improves the perceived QoL of patients.
User-centered care, engagement, and user’s orientation preference in postpartum care of quality: practitioner-postpartum women interdependence mediation analysis
Authors: Chou Ying-Chyi , Linda Linda , Lu Ching-Hua
Published: May 2022

Postpartum or “zuo yue zi” services are well-received among Chinese communities such as Taiwan, China, Singapore, and Malaysia. The postpartum services provided by the confinement center or one-month home confinement are designed to support the needs of postpartum women and to help in regaining their health. The goal of this research was to analyse the impact of postpartum women-centered care towards the quality of the postpartum care. Engagement was proposed as the mediating variable to investigate whether postpartum women-centered care can drive the postpartum women’s engagement and, eventually, improve the quality of care. In addition, patient-practitioner orientation preference was tested whether it moderates the relationship between postpartum women-centered behavior and quality of care. 80 female participants who had the experience of using postpartum service in Taiwan were recruited. The analysis results showed that postpartum women-centered care had significant and positive effect on quality of care. Meanwhile, the mediating effect of postpartum women engagement and the moderating effect of orientation preference were not significant.
A multi-modal fusion framework for continuous sign language recognition based on multi-layer self-attention mechanism
Authors: Xue Cuihong , Yu Ming , Yan Gang , Qin Mengxian , Liu Yuehao , Jia Jingli
Published: May 2022

Some of the existing continuous sign language recognition (CSLR) methods require alignment. However, this is time-consuming, and breaks the continuity of the frame sequence, and also affects the subsequent process of CSLR. In this paper, we propose a multi-modal network framework for CSLR based on a multi-layer self-attention mechanism. We propose a 3D convolution residual neural network (CR3D) and a multi-layer self-attention network (ML-SAN) for the feature extraction stage. The CR3D obtains the short-term spatiotemporal features of the RGB and optical flow image streams, whereas the ML-SAN uses a bi-gated recurrent unit (BGRU) to model the long-term sequence relationship and a multi-layer self-attention mechanism to learn the internal relationships between sign language sequences. For the performance optimization stage, we propose a cross-modal spatial mapping loss function, which improves the precision of CSLR by studying the spatial similarity between the video and text domains. Experiments were conducted on two test datasets: the RWTH-PHOENIX-Weather multi-signer dataset, and a Chinese SL (CSL) dataset. The results show that the proposed method can obtain state-of-the-art recognition performance on the two datasets, with word error rate (WER) value of 24.4% and accuracy value of 14.42%, respectively.
RETRACTED: Novel algorithm for multivariate time series crash risk prediction using CNN-ATT-LSTM model
Authors: Deva Hema D. , Ashok Kumar K.
Published: May 2022

This article has been retracted. A retraction notice can be found at https://doi.org/10.3233/JIFS-219433.
Hybrid-attention and frame difference enhanced network for micro-video venue recognition
Authors: Wang Bing , Huang Xianglin , Cao Gang , Yang Lifang , Wei Xiaolong , Tao Zhulin
Published: May 2022

Many micro-video related applications, such as personalized location recommendation and micro-video verification, can be benefited greatly from the venue information. Most existing works focus on integrating the information from multi-modal for exact venue category recognition. It is important to make full use of the information from different modalities. However, the performance may be limited by the lacked acoustic modality or textual descriptions in uploaded micro-videos. Therefore, in this paper visual modality is explored as the only modality according to its rich and indispensable semantic information. To this end, a hybrid-attention and frame difference enhanced network (HAFDN) is proposed to generate the comprehensive venue representation. Such network mainly contains two parallel branches: content and motion branches. Specifically, in the content branch, a domain-adaptive CNN model combined with temporal shift module (TSM) is employed to extract discriminative visual features. Then, a novel hybrid attention module (HAM) is introduced to enhance extracted features via three attention mechanisms. In HAM, channel attention, local and global spatial attention mechanisms are used to capture salient visual information from different views. In addition, convolutional Long Short-Term Memory (convLSTM) is enforced after HAM to better encode the long spatial-temporal dependency. A difference-enhanced module parallel with HAM is devised to learn the content variations among adjacent frames, which is usually ignored in prior works. Moreover, in the motion branch, 3D-CNNs and LSTM are used to capture movement variation as a supplement of content branch in a different form. Finally, the features from two branches are fused to generate robust video-level representations for predicting venue categories. Extensive experimental results on public datasets verify the effectiveness of the proposed micro-video venue recognition scheme. The source code is available at https://github.com/hs8945/HAFDN.
RETRACTED: Curative effect of pop light music on depression patients based on improved fuzzy algorithm
Authors: Li Hao
Published: May 2022

This article has been retracted. A retraction notice can be found at https://doi.org/10.3233/JIFS-219433.
Sensory evaluation of customer satisfaction using type-2 fuzzy logic
Authors: Abiyev Rahib H. , Sadikoglu Gunay , Alsalihi Adnan , Abizada Rufat
Published: May 2022

Sensory experiences that include vision, hearing, touching, smelling and tasting are important parameters that enable people to trade effectively in retail stores. In this study, based on multisensory attributes the evaluation of customer satisfaction is considered using fuzzy set theory and conjoint analysis. Fuzzy set theory is one of the best methodologies for describing the meaning of linguistic values that express customer preferences. However, there may be different customer and expert opinions in the evaluation of preferences by expressing linguistic values. In the paper, a type-2 fuzzy set is used to handle these uncertainties. This paper proposes the combination of type-2 fuzzy sets and conjoint analysis in order to evaluate customer satisfaction using customer opinions about sensory variables such as sight, sound, taste, touch and smell when purchasing goods in retail stores. For this purpose, using statistical survey results and type-2 fuzzy sets the customer satisfaction degrees were determined. The methodology used for the determination of customer satisfaction is based on conjoint analysis that uses the similarity measure to determine the closest opinions of the customers and experts for the evaluation of customer satisfaction degrees. The obtained experimental results indicate the efficiency of the presented approach in the determination of customer satisfaction in retail markets.