bluuebunny/crossref_metadata_2025 huggingface dataset:
Перспективы развития образовательных технологий при подготовке специалистов авиационного персонала
Authors: Иванова Мария Олеговна
Published: November 2019

При подготовке авиационного персонала необходимо использовать современные образовательные технологии для повышения эффективности обучающих программ и обеспечения высокого качества подготовки специалистов для гражданской авиации. Традиционные образовательные технологии для аудиторных занятий предлагается дополнять интерактивным компонентом, а подготовку авиационного персонала на тренажерах или с использованием других технических средств дополнять технологиями виртуальной реальности. В условиях ограниченного ресурсного обеспечения и высокой стоимости тренажерной подготовки авиационного персонала в качестве перспективной предлагается сетевая форма реализации образовательных программ. Представляется целесообразным использование дополнительных технологий, применение которых возможно в рамках самообразования, такие как он-лайн курсы, т.е. цифровые технологии в образовании, позволяющие специалистам авиационного персонала дистанционно осваивать знания, необходимые для успешного обучения в учебных заведения или авиационных учебных центрах
Introduction: Life Writing and European Identities
Authors: Huisman Marijke , Rensen Marleen
Published: November 2019

Since the turn of the millennium, life writing has been a burgeoning field, with identity formation as one of its key themes. In terms of identity ‘Europe’ is still relatively understudied, despite the fact that biographies and autobiographies have long been used to constitute or foster European identities, as is the case, for example, with respect to the so-called ‘founding fathers’ of the EU. Life writing bears at least as much potential to challenge such master narratives of Europe and make an important contribution to the ongoing debate about European identity. This special issue on life writing and European identity illustrates this, in articles ranging from Ai Weiwei’s art exhibition #SafePassage (2016) and the (contested) dichotomy of Western and Eastern European modernity in Vesna Goldsworthy’s memoir Chernobyl Strawberries (2005), to life in post-war Norway in Karl Ove Knausgard’s bestselling novel cycle Min Kamp (2009–2011) and the meta-biographical work of novelist A.S. Byatt.
Consideraciones sobre moda, estilo y tendencias
Authors: Doria Patricia
Published: November 2019

La Moda según Lipovetsky, se define como una búsqueda frenética de la novedad, yuna forma de venerar el presente. Estos conceptos se encuentran relacionados entre sí y acordesa una sociedad abierta en una cultura en la cual los valores primordiales son el placer, la búsqueda permanente de pertenecer a un grupo y al mismo tiempo ser diferente, y único.Esta exclusividad conlleva a tener o desarrollar un estilo específico. El estilo se define como unmodo de expresión básico y distintivo, la relación del estilo con las modas, es del orden de logeneral con lo particular. La moda en estos casos toma una posición de imperante y de regidoradel mundo del buen gusto, pero aún así, hay pequeñas modas que se instauran dentro de otrasesferas de no tanta envergadura y que son denominadas: estilos.
Al compás de la revolución Interactiva. Un mundo de conexiones
Authors: Onofre Elena
Published: November 2019

El impacto que genera la revolución interactiva en el escenario actual es equivalenteal producido por la revolución industrial, la aparición de la imprenta o la revolución copernicana. La gran diferencia entre estos hechos que han provocado cambios de paradigma y decosmovisión en la historia de la humanidad, es que la revolución interactiva se ha instalado enla sociedad en tan solo dos décadas, mientras que la penetración del industrialismo, la masificación y la accesibilidad a la palabra impresa, y más aún, la aceptación de la teoría copernicana,necesitaron decenas de generaciones para anclar en la sociedad.Las señales que caracterizan al escenario dominado por las tecnologías de la información y dela comunicación, ejercen una presión constante y sostenida sobre el modelo de aproximaciónal campo profesional que proponen las instituciones académicas.En este escenario dominado por la ubicuidad, la comunicación multidireccional y los públicosparticipativos multitasking, la dinámica institucional debería adoptar, si no en todas, en las másinnovadoras de sus propuestas formativas, el ritmo que demanda una sociedad dominada porel vértigo del descarte.Tenemos la necesidad de estar continuamente informados sobre múltiples temas y esto nosobliga a recargar de significado no solo los objetos de consumo sino aquello que hacemos comoprofesionales.
Diseño en Argentina. “Hacia la construcción de nuevos paradigmas”
Authors: Mon Laureano
Published: November 2019

Reflexión acerca de la producción actual del diseño de indumentaria y textil en Argentina, sus diálogos con otras disciplinas productivas y las problemáticas para abordar los desarrollos actuales desde las teorías tradicionales.
Baño, De Loof y Romero, tres revolucionarios de la moda y el arte en Buenos Aires
Authors: Lescano Victoria
Published: November 2019

Andrés Baño, Sergio De Loof y Kelo Romero representan tres casos de artistas-diseñadores e íconos de la Primera Bienal de Arte Joven, el movimiento de moda que en marzo de 1989 ofició de correlato estético y manifiesto luego del retorno a la democracia. Aquí un recorrido por sus obras y sus happenings más recientes
La aventura de la fotografía como arte de la moda
Authors: Muzzarelli Federica
Published: November 2019

La moda y la fotografía, ya a mediados del siglo XIX, son dos fetiches perfectos paraexpresar el alma del Modernismo que se avecina y ambas incorporan, de manera ejemplar,ciertas transformaciones en el vestir y en la estética de la contemporaneidad que caracterizan,profundamente, el inicio del siglo XX. Durante el siglo XIX, sin embargo, la fotografía compite,ferozmente, con la tradición pictórica para compartir un espacio demasiado estrecho para dospretendientes exigentes: el del Arte. Por lo tanto, antes de convertirse en una de las herramientas claves para la construcción de un imaginario de la moda, la fotografía busca su identidad,durante varias décadas, en un proceso que la llevará a la industria de la moda entre la intuiciónbrillante de diseñadores geniales, pioneras empresas editoriales y primeros ejemplos de profesionalidad de autor.
Diseño paramétrico. El gran desafío del siglo XXI
Authors: Navarrete Sandra
Published: November 2019

Estamos habituados a responder con el diseño a los nuevos modelos conceptuales que emergen de los cambios de paradigmas, de los teóricos y críticos, de las referencias epistemológicas internacionales. El diseño paramétrico se nos presenta en una situación diferente. De la complementariedad con otras disciplinas (de base eminentemente tecnológica), se ha generado una nueva forma de proyectar, atendiendo al proceso y sus múltiples variaciones, pero con escasa argumentación teórica. Se asiste a numerosos encuentros de esta temática en los que se cae en un éxtasis formal, que pareciera no necesitar mayores explicaciones. Pero, dado que el diseño está al servicio de la sociedad (no es arte autoreferencial), surge la imperante necesidad de encontrar el sustento conceptual a esta nueva modalidad de praxis.
El diseño de packaging y su contribución al desarrollo de pequeños y medianos emprendimientos
Authors: Brizuela Leandro
Published: November 2019

El presente trabajo refiere a la problemática del diseño de packaging orientado hacia pequeños y medianos emprendimientos de diseño que requieren de packaging innovadores, personalizados y de baja serie.El objetivo de este trabajo es dar a conocer los requerimientos generales que se deben considerar al emprender un proyecto de diseño de packaging de modo que presente mayores posibilidades de éxito. Para tal fin, se establecen una serie de pautas, identificando los puntos mas sensibles e influyentes para lograr que el Sistema PP (Packaging + producto) se convierta en un elemento estratégico en el punto de venta.En esta publicación se presenta además un marco metodológico para el análisis de una serie casos de pequeños y medianos emprendimientos locales que servirán de ejemplo para clarificar las cuestiones troncales de este trabajo.
Renacimiento, Manierismo, Barroco
Authors: Cravino Ana
Published: November 2019

El diseño de interiores del Renacimiento, Manierismo y Barroco se caracterizó por empleo de formas estilísticas de la antigüedad greco-romana y por la utilización de un sistema ordenado de proporciones geométricas. La espacialidad así configurada fue evolucionando de propuestas simplificadas y definidas a soluciones de gran complejidad y ambigüedad.
Siglo XIX
Authors: Garófalo Gabriela
Published: November 2019

El diseño interior decimonónico hasta la mitad del siglo estará dominado por dos propuestas: por un lado, el neoclasicismo – racional y universalista –; por el otro, el neogótico – emotivo y localista –. Sin embargo, a fines de siglo la diversidad había penetrado profundamente en el pensamiento de los europeos materializándose en las búsquedas del diseño ecléctico.
De lo Trans / Inter
Authors: Taquini Graciela
Published: November 2019

El escrito enuncia la capacidad de las operaciones artísticas de transmutar no sólo los materiales, sino también los soportes, los formatos y los lenguajes con el fin de transformar en acto o en proceso una imagen eidética y otorgarle un nuevo sentido. Esta mezcla constituye una fuerte tendencia del arte de hoy y coloca otros cimientos que fundan nuestro mundo presente.
Fusión de instantes
Authors: Niedermaier Alejandra
Published: November 2019

Se tratará de establecer cuan “consanguíneas” son las imágenes resultantes de la fotografía, el cine y el video. A partir de este concepto se estudiará a la fotografía como el componente molecular que habita en los lenguajes mencionados. Para ahondar en la íntima relación de éstos se ejemplificará con tres trabajos autorales que presentan distintos modos de enunciación.
Comunikación y subjetivid@d. Algunas reflexiones en el borde de la red
Authors: Belmes Débora
Published: November 2019

El mundo actual constituye un escenario inédito para la humanidad: las comunicaciones y junto con ellas, las nuevas tecnologías, han colaborado en la complejización y/o modificación de conceptos vinculados a la noción de presencia, tiempo, existencia, velocidad, actualidad, simultaneidad, espacio, lugar, conexión, horizontalidad, verticalidad. Subjetividad, sociedad y cultura se constituyen en productores y producto que se afectan en forma recursiva, transformando sus relaciones y sus vínculos. La idea no es abolir modos de pensar sino incorporar y producir nuevas miradas que permitan capturar lo actual y apreciar los efectos y el impacto que la cotidianeidad y sus aparatos para comunicar imprimen y configuran en las subjetividades.
El séptimo arte en la era de la revolución tecnológica
Authors: Sabeckis Camila
Published: November 2019

Desde sus comienzos el cine se ha valido de los inventos tecnológicos, la incorporación de nuevas tecnologías –el sonido, el color, la tridimensión– le permitieron evolucionar y convertirse en una gran industria del espectáculo. En las últimas dos décadas, las técnicas digitales han sido absorbidas en todo el sistema de producción cinematográfico. Así, la industria del cine continúa incorporando innovacionestecnológicas que le permitan renovarse y seguir generando éxitos de taquilla. En la actualidad los avances tecnológicos han posibilitado también el surgimiento de nuevas formas de hacer, ver y analizar un film. El cine ya no es lo que era, el celuloide fue el punto de partida, pero los formatos se han ido modificando y adecuando a la nueva época que estamos viviendo. En el presente ensayo se buscará reflexionar acerca de las implicancias de esta unión entre cine y nuevas tecnologías tanto en la producción cinematográfica, como en la recepción por parte del espectador; indagando en las nuevas formas de realización y exhibición, de manera tal de poder perfilar el nuevo panorama del séptimo arte en esta era de revolución tecnológica queestamos viviendo.
Claves de identidad del programa Identidades Productivas
Authors: Porrúa Marina
Published: November 2019

Diseño Colectivo, Identidad, Diversidad , Articulación y Red, son las claves que identifican al programa Identidades Productivas, de la Secretaría de Cultura de la Nación, que, solidariamente con el “Plan de Capacitación en Diseño: Producir redes para potenciar recursos, proyectos e identidades”, de la Universidad Nacional de Mar del Plata, promueven, desde 2002, el desarrollo de grupos dedicados al diseño y producción colectiva de sistemas de objetos, portadores de identidades culturales, con rango de Colección provincial y/o nacional.
Lectura, escritura y oralidad en la escuela desde la perspectiva sociocultural
Authors: Galindo-Lozano Denys Paola , Doria-Correa Rudy
Published: November 2019

En este documento se muestran los resultados de una investigación para describir el enfoque de enseñanza del lenguaje que poseen los maestros de básica primaria, así como la relación de estos enfoques con sus prácticas de aula. Se asumió el paradigma cualitativo, con base en el método de investigación-acción, donde participan cinco maestros de básica primaria, de una institución educativa colombiana. Los resultados indican una concepción estructuralista, desde la cual se orientan las prácticas de enseñanza de los maestros en el ejercicio cotidiano de sus clases de lenguaje. Esto debido a que se percibe el detonante de la transcripción en la escritura, la representación gráfica de la palabra y la memorización en la oralidad. Se concluye con la necesidad de transformar la práctica de los maestros en el área de lenguaje hacia nuevos escenarios de enseñanza, que propicien el análisis profundo de los textos y los discursos, en cuanto a: sus condiciones de producción, sus intenciones y sus efectos entre los usuarios de la lengua, en distintos contextos sociales y culturales.
La educación secundaria y superior en Colombia vista desde las pruebas Saber.
Authors: Castro Mayerlin , Ruíz Jorge Vicente
Published: November 2019

Las pruebas estándar generan debate al evaluar la calidad de la educación.  Empero, son una herramienta de caracterización de los estudiantes. Colombia parece ser el único país del mundo en que se puede hacer el seguimiento de la prueba estándar de secundaria y universitaria para el mismo estudiante.  El estudio busca caracterizar a los estudiantes que presentaron ambas pruebas.  Se llevan a cabo tablas de contingencia en EXCEL para los estudiantes en Colombia que lograron terminar su bachillerato y pregrado, y presentaron la prueba Saber 11 en 2005-2006 y 4-5 años después  Saber Pro en instituciones tanto técnicas como universitarias (N=25,980), y solo universitarias (N=18,845). Seis de cada diez estudiantes que terminaron sus estudios superiores asistieron a un colegio o a una universidad del sector privado. Aproximadamente dos de cada tres estudiantes que terminan sus estudios superiores lo hacen en una universidad.  Hay diferencias significativas de las pruebas Saber 11 por género y esta prueba se encuentra muy correlacionada con la prueba Saber Pro.  Los resultados de las pruebas Saber Pro en universidades oficiales son superiores a aquellos de las públicas.
A TUTELA JURISDICIONAL DOS DIREITOS SOCIAIS: UMA ANÁLISE DO PAPEL DA ADMINISTRAÇÃO PÚBLICA E DO PODER JUDICIÁRIO
Authors: Fontana Helena Grassi
Published: November 2019

O presente artigo tem por objetivo discutir e instigar a análise sobre a importância e o papel da Administração Pública e do Poder Judiciário, enquanto responsáveis e guardiões da efetivação dos direitos. Além disso, analisa a tutela jurisdicional dos direitos sociais, o que pode representar um confronto com princípios basilares do direito e das estruturas do Estado. Com a promulgação da Constituição da República Federativa do Brasil de 1988, houve no Estado brasileiro a adoção do modelo denominado de tripartição dos poderes. Contudo, para que esse modelo exista, faz-se necessário que cada um dos poderes, Executivo, Legislativo e Judiciário, cumpra os atos correspondentes às suas funções. Porém, algumas vezes ocorre a confusão entre as funções destes poderes, que acabam por não ser tão harmônicos e independentes entre si. Em conclusão, percebeu-se que o papel da Administração Pública e do Poder Judiciário são indissociáveis e fundamentais para a manutenção do bem-estar social. Para investigar e analisar o tema, o problema e as hipóteses levantadas, foi utilizado o método indutivo na fase de investigação; na fase de tratamento de dados será o cartesiano e indutiva. Foram acionadas as técnicas do referente, da categoria, dos conceitos operacionais, da pesquisa bibliográfca, bem como os estudos das disposições legais sobre o tema e os entendimentos apresentados pela doutrina pátria.
ATIVISMO JUDICIAL E POLÍTICAS PÚBLICAS
Authors: Fonseca Junior Mauro Augusto Ferreira da , Teixeira Carla Noura
Published: November 2019

O objetivo deste trabalho é apresentar como ocorre a intervenção judicial nas Políticas Públicas por meio do chamado ativismo judicial, bem como demonstrar as consequências de tal intervenção para o ordenamento o qual é pautado na Teoria da Separação de Poderes. Para tanto, se buscou explicitar a difculdade de se chegar a um conceito fechado para Políticas Públicas, visto a complexidade do tema e a pluralidade de fatores envolvido para se chegar ao que é de fato Políticas Públicas. Feito isso, se colocou como a fgura do Ativismo Judicial interfere na Administração Pública, isso porque é a Administração que tem o domínio das Políticas Públicas, logo quando ocorre a intervenção nas Políticas Públicas, ela ocorre, em última análise, na própria Administração. Por fm, enfatizou-se a relação e as consequências do Judiciário intervir nas Políticas Públicas por meio do ativismo, e a forma com que isso se dá no sistema em si, avaliando possíveis limites para a intervenção e, em última análise, se é de fato necessária a intervenção.
REDUCCIÓN DE LA REMUNERACIÓN NO CONSENSUADA ENTRE TRABAJADOR Y EL EMPLEADOR EN EL CONTEXTO PERUANO
Authors: Seminario Morante Bismarck Jefferson
Published: November 2019

En este artículo se hace un estudio sobre la posibilidad de que el empleador proceda a disminuir la remuneración de sus trabajadores sin consultar con estos últimos, pues, como es sabido, las empresas durante su existencia en el mercado, no siempre mantienen una economía estable, pueden atravesar por momentos de crisis que exigen tomar algunas medidas para ahorrar costos e ir resurgiendo de a pocos, ya que de no actuar así cabe el riesgo de terminar en la extinción empresarial lo que obviamente perjudicaría a todos, tanto al empleador como al trabajador. Por otro lado, resulta interesante elaborar una crítica sobre la Casación N° 3711-2016-Lima, en la medida que, en ella, la Corte Suprema del Perú fjó un listado de supuestos en donde sería permitida la reducción del salario no consensuada entre trabajadores y el empleador; sin embargo, dichos supuestos no fueron explicados individualmente, lo que implica la necesidad de emitir una punto de vista doctrinario que dé luces sobre lo que es viable y lo que no, según corresponda.
Ethnic Differences in Home Related Maternal Stress: Muslim and Jewish Mothers
Authors: Saadi Diana , Schnell Izhak , Tirosh Emanuel , Agay-Shay Keren
Published: November 2019

Parental stresses are normal responses to raising children. They are affected by stresses parents and children accumulate and bring to their interrelations. Background factors like economic difficulties or the relations between the parents may affect parental stresses as well as demographic and environmental factors like noise and access to urban parks. Most studies on parental stress are based on a verified psychological questionnaire. We suggest using frequency domain heart rate variability index (HRV) to measure parental stress enabling, by thus, the measurement of physiological aspects of stress and risk to health. Parental stress is measured as the difference between HRV accumulated at home while staying with the children and without the husband and HRV measured in the neighborhood while staying without the children and the husband. We use the index to compare differences among Muslim and Jewish mothers in exposure to maternal stress at their homes and to expose the factors that predict differences in maternal stress. We found that Muslim mothers suffer from home-related maternal stress while Jewish mother do not. Number of children and ethnically related environmental aspects predict differences in maternal stress between Muslim and Jewish mothers. Muslims' lower access to parks stems from lack of home garden and parks in their neighborhoods in the Arab towns but mainly by restrictions on Muslim women's' freedom of movement to parks. Despite differences in levels of noise at home and in the status of the mother in the household, these factors did not predict differences in parental stress. Instead, the study highlights the crucial role of greenery and freedom of movement to parks in moderating home-related maternal stress.
The TRAX Light-Rail Train Air Quality Observation Project
Authors: Mendoza Daniel L. , Crosman Erik T. , Mitchell Logan E. , Jacques Alexander , Fasoli Benjamin , Park Andrew M. , Lin John C. , Horel John
Published: November 2019

Observing air quality from sensors onboard light rail cars in Salt Lake County, Utah began as a pilot study in 2014 and has now evolved into a five-year state-funded program. This metropolitan region suffers from both elevated ozone levels during summer and high PM2.5 events during winter. Pollution episodes result predominantly from local anthropogenic emissions but are also impacted by regional transport of dust, chemical precursors to ozone, and wildfire smoke as well as being exacerbated by the topographical features surrounding the city. Two electric light-rail train cars from the Utah Transit Authority light-rail Transit Express (“TRAX”) system were outfitted with PM2.5 and ozone sensors to measure air quality at high spatial and temporal resolution in this region. Pollutant concentration data underwent quality control procedures to determine whether the train motion affected the readings and how the sensors compared against regulatory sensors. Quality assurance results from data obtained over the past year show that TRAX Observation Project sensors are reliable, which corroborates earlier preliminary validation work. Two case studies from summer 2019 are presented to illustrate the strength of the finely-resolved air quality observations: 1) an elevated ozone event and 2) elevated particulate pollution resulting from 4th of July fireworks. The mobile observations were able to capture spatial gradients as well as pollutant hotspots during both of these episodes. Sensors have been recently added to a third light rail train car, which travels on a north-south oriented rail line along which we were unable to monitor air quality previously. The TRAX Observation Project is currently being used to provide reliable pollutant data for health studies and inform urban planning efforts. Links to real-time data displays and updated information on the quality-controlled data from this study are available at https://atmos.utah.edu/air_quality/trax/.
Identification of Malignant Mesothelioma Risk Factors through Association Rule Mining
Authors: Alam Talha Mahboob
Published: November 2019

Malignant mesothelioma is a rare proliferative cancer that develops in the thin layer of tissues surrounding the lungs. Malignant mesothelioma is associated with an extremely poor prognosis and the majority of patients do not show symptoms. The epidemiology of mesothelioma is important for the identification of disease. The primary aim of this study is to explore the risk factors associated with mesothelioma. The dataset consists of healthy and mesothelioma patients but only mesothelioma patients were selected for the identification of symptoms. The raw data set has been pre-processed and then the Apriori method was utilized for association rules with various configurations. The pre-processing task involved the removal of duplicated and irrelevant attributes, balanced the dataset, numerical to the nominal conversion of attributes in the dataset and creating the association rules in the dataset. Strong associations of disease’s factors; asbestos exposure, duration of asbestos exposure, duration of symptoms, erythrocyte sedimentation rate and Pleural to serum LDH ratio determined via Apriori algorithm. The identification of risk factors associated with mesothelioma may prevent patients from going into the high danger of the disease. This will also help to control the comorbidities associated with mesothelioma which are cardiovascular diseases, cancer-related emotional distress, diabetes, anemia, and hypothyroidism.
Statistical Analysis and Forecasting of Price and Mileage Correlation for Second-hand Cars in Australia
Authors: Agokei Chinedu G. , Afa Bomonyo J.
Published: November 2019

In developed countries, especially the big-sized ones like Australia and the USA, a car is almost an inevitable necessity to carry out daily activities. Due to this, used cars have become a great alternative to brand new cars because of their cost effectiveness. In this work, estimation of prices of used cars based on numerous factors is studied statistically. Data is based on prices of used cars sold across Australia. Statistical methods like correlation and permutation tests using linear regression model, exact tests and non-parametric bootstrapping is implemented to study the relationship of price with mileage and year of manufacture of the car using p-values and null hypothesis. Predictions are also made on the price by calculating a 95% confidence interval (CI) of median prices in small portions of the dataset. The study presents potential ideas for understanding correlation between variables and parameters in business studies.
Field Application of Tubing Deployed Inflow Control Devices ICDs to Repair Liner Failures in SAGD Completions: Diagnosis, Design, Deployment and Outcome
Authors: Saeedi Majid , Cowle Jason , Cross Ryan , Stevenson Jesse , Tuttle Aubrey
Published: November 2019

Liner failure is one of the key risks in operation of SAGD producers and is often associated with erosion as a result of steam production (Burke, L. et al. 2018). Among various intervention methods, tubing deployed inflow control devices (ICDs) have been used to remediate wells. In this paper, two field examples of using tubing ICDs are discussed, one inside a wire wrapped screen liner and the other inside a liner deployed ICD system.

Liner failures were diagnosed by analyzing the temperature data from fibre optics along with the performance indicators of the ESP pumps. Various remediation plans such as patching the failed intervals, using tubing ICDs or drilling a parallel lateral were considered. Using tubing deployed ICD systems along with blanked intervals was selected as the most practical solution to recover productivity from these wells. To size the ICDs and length of segments, a range of emulsion production volumes as well as estimated corresponding vapor and gas volumes were assumed. Furthermore, the risk of creating new hot points near the existing failed points or vapor producing intervals was considered.

The well workovers involved detailed planning of operations and services to effectively achieve cleanouts, maintain adequate inner wellbore diameter to run the swell packers and correlate DTS data with workover findings. The workover involved gauge runs, a jet-vac clean-out, a multi-finger caliper log and mud circulation of the wellbore for final solid removal to ensure successful installation of the new ICD systems.

The wells were put on production initially with low drawdown and slowly ramped up to let the packers set and sand to form bridges. After a few months of production, the wells were fully ramped up with production rate increasing 2 to 5 times the pre-workover rates. ESP pump performances is stable in both wells and the fibre optic temperature data show that failed liner intervals and hot points are well managed.

The intent of this paper is to share the processes and factors considered in using remedial ICDs and the learnings from the workover operations and startup of the wells.
Prognostics Thermal Well Management: A Review on Wellbore Monitoring and the Application of Distributed Acoustic Sensing DAS for Steam Breakthrough Detection
Authors: Soroush Mohammad , Roostaei Morteza , Fattahpour Vahidoddin , Mahmoudi Mahdi , Keough Daniel , Cheng Li , Moez Kambiz
Published: November 2019

Accurate prediction of flow regime and flow profile in wellbore is among the main interests of production engineers in the quest of optimizing wellbore production and increasing reliability of downhole completion tools especially in SAGD projects. This study introduces a methodology for wellbore monitoring by detecting flow phase and flow regime. In order to develop this method, an advanced multi-phase flow injection experiment was designed and commissioned.

A flow injection setup was developed to test distributed fiber optic sensor installation under different operating conditions, including multi-phase flow (oil, brine and gas), and flow fraction scenarios. Different signal processing methods were applied to extract meaningful features and filter the noise from the raw signals. A statistical analysis was performed to assess the trend of the driven data. Then, typical SAGD models were simulated to assess the results of experimental setup for scale-up purpose and determination of local breakthrough of steam along the well.

Results showed that the Distributed Acoustic Sensing (DAS) data contains different levels of signals for each phase and flow regime. We also found that some level of uncertainties is involved in relating the flow regime and DAS information which could be resolved by improving the sensor installation procedure. In addition, the application of data-driven machine learning methods was found necessary to interpret the signal patterns. Initial results have shown that steam breakthrough along the well can be detected using real time DAS high energy/frequency signals. It can be concluded that including the DAS along with Distributed Temperature Sensing (DTS) is necessary to provide a better picture of steam conformance and SAGD wellbore monitoring. The limitations of the current experimental setup restricted further conclusions regarding the hybrid DAS and DTS application.

This paper is a part of an ongoing project to address the application of the combined DAS and DTS in SAGD projects. The ultimate goal is a downhole monitoring system to oversee the flow phase, flow regime and sand ingress in thermal application. The next phase will address the required improvements for developing a flow loop to handle high temperatures, include sand production and mimic thermal operation conditions.
Geomechanical Simulations to Design Well Integrity
Authors: Yuan Yanguang , Boone Thomas J.
Published: November 2019

Rock deformation and fracturing is an important causal mechanism that can compromise well integrity. Geomechanical simulation is a valuable tool to investigate this mechanism and connect well tubular designs with reservoir development strategies. Utilizing relevant field examples, this paper describes a work flow in these regards.

Two example simulation approaches are described. One is to use a composite casing/cement/rock model in a reservoir of complex geology to compute maximum strain, dogleg severity, and ovality/restriction in the casing along the well trajectory. Different well design parameters, such as casing size, grade, and cement thickness, can be iterated against different reservoir production strategies. All these efforts are to arrive at an optimized design. The other approach is to calculate localized shear displacement along a weak plane that will be imposed on well tubulars during reservoir activities. The resulting design is optimized by altering well placement and stimulation/production schedules.

The above workflow has been proven in various field applications. Experience is shared in this paper. It is hoped this work can demonstrate that the optimal management of well integrity can be achieved by an integrated approach that designs appropriate tubulars and adjusts reservoir activities. Placing well tubulars in the context of rock deformation, geomechanical simulation is the best tool to connect the reservoir activities with the well tubular designs and therefore, can potentially offer a cost-effective well integrity management program.
SAGD Circulation Strategy Utilizing Flow Control Devices
Authors: Batias Jeremie , Ortiz Julian , Nespor Kristian
Published: November 2019

For ConocoPhillips, technology is a key driver and development accelerator to continuously improve its SAGD operations. The deployment of conventional Flow Control Device (FCD) technology in Surmont has allowed ConocoPhillips to realize shorter circulation times and higher oil production rates. These benefits have been realized while ensuring liner and well integrity.

Optimizing the well start-up process in SAGD has been a challenge at Surmont and in the industry in general. SAGD well start-up involves heating bitumen through a mostly conductive process to allow the SAGD mechanism to initiate. A recent breakthrough in the circulation strategy for wells equipped with FCDs at Surmont was developed and implemented by the ConocoPhillips Technology and Operation teams. This new approach has been possible by integrating FCD characterization and erosion testing with complex engineering principles such as convective heating, sand control, reservoir multiphase flow and wellbore flow dynamics. ConocoPhillips commenced the implementation of the new strategy in the field between 2015 and 2016 with great success. Benefits of this circulation strategy by fully utilizing the FCD technology are numerous, including a reduction of circulation duration, substantial increase in early time oil and liquid production and accelerated well ramp-up.

The paper begins by presenting the concept of this new circulation strategy. Then, details on various SAGD mechanisms and associated FCD physics are explained. Finally, field data is presented to illustrate the successful implementation of this strategy along with an analysis of the operating results.
Transcriptome sequencing of a keystone aquatic herbivore yields insights on the temperature-dependent metabolism of essential lipids
Authors: Windisch Heidrun Sigrid , Fink Patrick
Published: November 2019

Background: Nutritional quality of phytoplankton is a major determinant of the trophic transfer efficiency at the plant-herbivore interface in freshwater food webs. In particular, the phytoplankton’s content of the essential polyunsaturated omega-3 fatty acid eicosapentaenoic acid (EPA) has been repeatedly shown to limit secondary production in the major zooplankton herbivore genus Daphnia. Despite extensive research efforts on the biological model organism Daphnia, and the availability of several Daphnia genomes, little is known regarding the molecular mechanisms underlying the limitations in Daphnia related to dietary EPA availability. Results: We used RNA-seq to analyse the transcriptomic response of Daphnia magna which were fed with two different diets — each with or without supplementation of EPA — at two different temperature levels (15 and 20°C). The transcripts were mapped to the D. magna genome assembly version 2.4, containing 26,646 translations. When D. magna fed on green alga, changing the temperature provoked a differential expression of 2,001 transcripts, and in cyanobacteria-fed daphnia, 3,385 transcripts were affected. The supplementation of EPA affected 1,635 (on the green algal diet), or 175 transcripts (on the cyanobacterial diet), respectively. Combined effects for diet and temperature were also observed (669 for the green algal and 128 transcripts for the cyanobacterial diet). Searching for orthologous genes (COG-analysis) yielded a functional overview of the altered transcriptomes. Cross-matched transcript sets from both feed types were compiled to illuminate core responses to the factors temperature and EPA-supplementation. Conclusions: Our highly controlled eco-physiological experiments revealed an orchestrated response of genes involved in the transformation and signalling of essential fatty acids, including eicosanoid-signalling pathways with potential immune functions. We provide an overview of downstream-regulated genes, which contribute to enhance growth and reproductive output. We also identified numerous EPA-responsive candidate genes of yet unknown function, which constitute new targets for future studies on the molecular basis of EPA-dependent effects at the freshwater plant-herbivore interface.
Prevalence of HIV, syphilis, and assessment of the social and structural determinants of sexual risk behaviour and health service utilisation among MSM and TG in Terai highway districts of Nepal: Findings based on an Integrated Biological and Behavioural Surveillance survey using respondent driven sampling
Authors: Storm Margrethe , Deuba Keshab , Damas Jose , Shrestha Upendra , Rawal Bir , Bhattarai Rajan , Marrone Gaetano
Published: November 2019

Background: Men who have sex with men (MSM) and transgender people are disproportionately affected by HIV and sexually transmitted infections. MSM and transgender people in Nepal experience considerable discrimination and marginalisation, they are subject to abuse from legal authorities and suffer from mental health issues. This study aims to assess the prevalence of HIV and syphilis, and how individual and socio-structural factors influence sexual risk behaviour and health care service uptake, among MSM and transgender women in the Terai highway districts of Nepal. Methods: A cross-sectional survey was conducted in June 2016 in eight Terai highway districts of Nepal, recruiting 340 MSM and transgender women through respondent driven sampling. The primary outcome variables were HIV and syphilis prevalence. The secondary outcome variables were sexual risk behaviour and health care service uptake. Logistic regression models were used to assess the individual and socio-structural determinants of sexual risk behaviour and health care service uptake. Results: The prevalence of HIV among MSM was 5%, whereas it was 13% in transgender women. The prevalence of active syphilis was 4% in MSM and 11% among transgender women. Among transgender women, 76% were involved in sex work, and 51% had experienced discrimination in one or more settings. In multivariable analysis, having visited an outreach centre was positively associated with condom use in the last sexual encounter among both MSM (AOR: 5.37, 95% CI: 2.42 - 11.94, p<0.001) and transgender women (AOR: 2.37, 95% CI: 1.12 – 5.02, p=0.025). Moreover, transgender women who reported being open towards family about sexual identity/behaviour were 2.4 more likely to have visited an outreach centre (AOR: 2.40, 95% CI: 1.04 – 5.57, p=0.041). Conclusions: The high prevalence of HIV and syphilis, as well as indicators of marginalisation and discrimination among transgender women, highlights the increased burden transgender women in Nepal are facing and the need for tailored interventions. Moreover, since health care service uptake is an important factor in determining sexual risk behaviour among MSM and transgender women in Nepal, outreach services should be scaled up.
Association of PD-1 polymorphisms with the risk and prognosis of lung adenocarcinoma in the northeastern Chinese Han population
Authors: huang Kun , Hu Erqiang , Li Wan , Lv Junjie , He Yuehan , Deng Gui , Xiao Jinling , Yang Chengcheng , Zhao Xinyu , Chen Lina , Wang Xinyan
Published: November 2019

Introduction Lung cancer is a leading cause of death from cancer worldwide, especially non-small cell lung cancer (NSCLC). The marker of progression in lung adenocarcinoma has been rarely studied. PD-1 is an effective drug target for the treatment of non-small cell lung cancer. The study of the effect of polymorphism on the progression of lung adenocarcinoma in the Han population of Northeast China may provide a valuable reference for the research and application of these drugs. Methods Chi-square test, Wilcoxon rank sum test, and classification efficacy assessment were used to teste SNPs of PD-1 in 287 patients and combined with clinical information. Results We successfully identified biomarkers (rs2227981, rs2227982, and rs3608432) that could distinguish the early stages and late stages of lung adenocarcinoma. Multiple clinical indicators showed significant differences among different SNP typing and cancer stages. Furthermore, this gene was confirmed to effectively distinguish the staging of lung adenocarcinoma with RNA-seq data in TCGA. Conclusions This indicated that the PD-1 gene and the SNPs on it could be used as markers for distinguishing lung adenocarcinoma staging in the Northeast Han population.
Intensive Home Treatment for adolescents in psychiatric crisis
Authors: Muskens Jet , Herpers Pierre C.M. , Hilderink Caroline , Deurzen Patricia A.M. van , Buitelaar Jan K. , Staal Wouter G.
Published: November 2019

Adolescents with acute psychiatric disorders are typically treated with long-term clinical admission. However, long term admission may be associated with a variety of negative outcomes. This pilot study presents a new model of care, that is, the combined application of intensive home treatment and the possibility of short term stay at a psychiatric high & intensive care. Methods In total 112 referred adolescents with mixed diagnoses participated in this longitudinal observational design. Clinical outcome was measured by the Health of the Nation Outcome Scales for Children and Adolescents (HoNOSCA) which measures the severity of multiple mental health problems. The HoNOSCA was clinician-rated at intake, after two months and after four months at discharge. Change in HoNOSCA total score was analysed with paired t-tests. Outcome moderators were gender, age, primary diagnosis, clinical admission, home treatment-time, medication and additional therapies. Follow up data were completed for 62 patients after two months and for 53 after four months. Results Participants aged between 11 and 18 years (M = 14.8 years, SD = 0.3; 52% female). Mean HoNOSCA total score at intake was 18.8 (SD = 5.2), after two months 13.0 (SD = 5.0); after four months resulting in a score of 9.3 (SD = 5.2). None of the moderators tested showed a significant effect on HoNOSCA scores. However, a control group could not be used because of the severe psychopathology and high risk for suicidality and the lack of an effective treatment intervention for a comparable study group. Conclusion With a symptom decrease of over 50% within four months as measured by the HoNOSCA, including less risk for hospitalization, this new model appears promising and of clinical relevance. Nevertheless, further research regarding stability of treatment outcome is warranted and evaluation of long-term effects of this model in follow-up studies is needed.
Downregulation of lncRNA DANCR promotes osteogenic differentiation of periodontal ligament stem cells
Authors: Wang Zhuo , Huang Yuanliang , Tan Luanjun
Published: November 2019

Backgrounds: Long non-coding RNAs (lncRNAs) have been widely known to have an appreciable effect in physiology and pathology. In tooth regeneration, periodontal ligament stem cells (PDLSCs) are regarded as a key effector, whereas, how lncRNA acts in the osteogenic differentiation of PDLSCs have not been completely understood. This study aims to find out the relationship between lncRNA DANCR and the proliferation and osteogenic differentiation of PDLSCs. Method: Microarray was used to observe the different expression of lncRNAs in differentiated and undifferentiated PDLSCs. And then osteogenic-related lncRNA, DNACR was screened out. To explore its effects on proliferation and osteogenic differentiation by constructing an overexpression and inhibition model. qRT-PCR was used to detect the mRNA expression of osteogenesis related genes. MTT assay was performed to assess the effects of DNACR on cell growth curve. To quantify the effects of DNACR on osteogenic differentiation of PDLCs, ALP staining and alizarin red was performed in basic culture medium and osteogenic medium. Data were statistically processed. Results: Compared with the undifferentiated PDLSCs, the alizarin red staining level was higher in differentiated PDLSCs. And the expressions of osteogenic differentiation marker genes Runt-related transcription factor 2 (Runx2), osteocalcin (OCN) and bone morphogenetic protein (BMP-2) were significantly increased in the differentiated PDLSCs. Furthermore, we noticed that comparing with control groups, the expression of LncRNA DANCR decreases markedly in osteogenically induced PDLSCs. DANCR promoted proliferation of PDLSCs, as evidenced by cell viability. Further investigation has proven that the downregulation of DANCR shows in the calcium sediment forming, alkaline phosphatase (ALP) activation and some osteogenic-related gene markers’ upregulation including Runx2, OCN and BMP-2, which finally results in the osteogenic differentiation of PDLSCs following the transfection and induction. Conversely, DANCR upregulation was shown to repress the osteogenic differentiation potential of PDLSCs. Conclusions: The osteogenic differentiation of PDLSCs has proven to related to the down regulation of lncRNA DANCR. And this paper throws light on the effects of DANCR in the process of PDLSCs’ osteogenic differentiation.
Lower serum 25-hydroxyvitamin D3 concentration is associated with higher pain and disability in subjects with low back pain: a case-control study
Authors: Pishgahi Alireza , Dolatkhah Neda , Shakouri Seyed Kazem , Hashemian Maryam , Amiri Atefeh , Reihany Morteza Delkhosh , Jahanjou Fatemeh
Published: November 2019

Objectives: Low back pain (LBP) is a common medical problem worldwide. The aim of this study is to evaluate the association between serum concentration of 25-hydroxivitamin D3 and functional disability in patients suffering from LBP in a sample of Azeri middle-aged subjects, North West of Iran .
Results: In this case-control study, 63 eligible patients with LBP and 55 healthy subjects enrolled in the study. Peripheral venous blood was taken for evaluating the serum concentration of 25-hydroxivitamin D3. We recognized factors related with LBP by multiple regression analyses. The average serum 25-hydroxivitamin D3 concentration in case group was significantly lower than that of the matched controlled group (26.25±15.95 vs. 34.20±14.92, p-value < 0.01 respectively). Subjects with vitamin D deficiency or insufficiency were more likely to exhibit LBP than subjects with normal serum 25-hydroxivitamin D3 concentration [(OR= 2.388, 95% CI (1.114 to 5.119)]. According to the partial correlation analysis, there was a reverse correlation between serum 25-hydroxivitamin D3 concentration with functional disability measured by Modified Oswestry Questionnaire (r = -.307, p = .017) and also with pain intensity according to Visual analogue Scale (VAS) score (r = -.268, p = .040) whilst adjusting for age, sex and body mass index (BMI).