bluuebunny/crossref_metadata_2025 huggingface dataset:
PAIXÃO DO AMOR ENUNCIADA EM FRAGMENTOS DE UM DISCURSO AMOROSO, DE ROLAND BARTHES
Authors: Brixner Silvana Regina Martins , Martins Geraldo Vicente
Published: November 2024

A linguagem do sujeito amoroso é composta e enunciada por discursos, denominados como figuras por Barthes; estas, acionadas no imaginário do sujeito, evocam sentidos múltiplos de reconhecimento, de vivência experimentada. Nos Fragmentos, o sujeito amoroso é o sujeito apaixonado representado por várias vozes repercutidas em toda a obra, em ecos e ressonâncias plenos de paixão. Para a semiótica, em uma abordagem inicial, temos as paixões, vistas a partir da semântica narrativa, como efeitos de sentido de qualificações modais que transformam o sujeito de estado. Na organização das estruturas modais, o sujeito pode estar modalizado por um querer, um poder, um dever ou um saber, permitindo que o objeto desejado torne o sujeito desejoso. Além desses pontos, a fundamentação teórica utilizada para este trabalho baseia-se em estudos desenvolvidos na semiótica discursiva e seus desdobramentos referentes à enunciação. Nessa empreitada, analisaremos o nível discursivo, o qual situa uma narrativa no tempo e no espaço, e o narrativo, com os actantes (sujeitos, objetos, destinadores e destinatários da narrativa), que se tornam atores do discurso; do primeiro, abordaremos também os procedimentos sintáticos de temporalização, espacialização e actorialização e os semânticos de tematização e figurativização, focalizando os efeitos de sentido desse discurso da paixão.  
Palavras-chave: discurso; enunciação; paixão.
Expressão e conteúdo
Authors: Nascimento Flaviano Batista
Published: November 2024

Tomando por base os preceitos da semiótica linguística, que também é conhecida como greimasiana, este trabalho visa estudar a expressão e o conteúdo no poema “Consoada”, de Manuel Bandeira, procurando demonstrar que a temática da aceitação da morte pode ser apreendida tanto pelo conteúdo posto, como fizeram alguns exegetas da obra do poeta, quanto pela expressão pressuposta, como tentei elucidar com esta análise.
SEMIÓTICA DISCURSIVA E LEITURA
Authors: Lindolfo Barbosa Jakecilene , FABIANO-CAMPOS SULEMI
Published: November 2024

Resumo: Este trabalho teve como principal objetivo analisar semioticamente o livro-imagem Onda (Suzy Lee) a partir do Percurso Gerativo do Sentido, considerando a característica semissimbólica do texto, ou seja, o diálogo indissociável entre as categorias do plano de expressão e as categorias do plano de conteúdo. A análise revelou que Onda (Suzy Lee) aborda a isotopia da infância como a passagem do estado de não saber para o estado do saber figurativizada pela experiência da descoberta do mar por uma garotinha. No texto, a artista mobiliza os formantes plásticos, os formantes figurativos e o próprio projeto gráfico-editorial, explorando as diferentes partes que compõem o livro-objeto (a capa, contracapa, folha de guarda, dobra), para fabricar o sentido da narrativa. Para alcançar tal objetivo, debruçamo-nos nos estudos de autores como Barros (2005), Fiorin (1990), Lara & Matte (2009), Floch (2001), Girão (2014; 2017) e Pietroforte (2020).
AS MODALIDADES VERIDICTÓRIAS E OS EFEITOS DE VERDADE E CUMPLICIDADE NA CRÔNICA “OS DOIS BONITOS E OS DOIS FEIOS”, DE RAQUEL DE QUEIROZ
Authors: Tiogo da Silva Emerson
Published: November 2024

O modo como o texto se organiza, dispondo os fatos apresentados ao leitor, orienta a apreensão dos sentidos nele construídos; nesse viés, a escolha pelo tipo de narrador passa sempre por uma intencionalidade discursiva mediada pela enunciação. Partindo desse pressuposto, buscaremos, neste trabalho, compreender como as projeções enunciativas contribuem para a obtenção de efeitos de verdade e cumplicidade na crônica “Os dois bonitos e os dois feios”, de Raquel de Queiroz. Por considerar que as projeções enunciativas indicam modos de presença do enunciador, adotaremos como instrumental teórico os elementos da sintaxe e da semântica propostos pela semiótica discursiva por meio da descrição e análise dos modos de organização textual dos mecanismos de debreagem e embreagem, assim como pelas relações estabelecidas entre as categorias de pessoa, tempo, espaço e os percursos figurativo e temático no texto, conforme assinala Fiorin (2016); também nos interessa, em consonância com Bertrand (2003), analisar questões em torno do ponto de vista e das posições enunciativas. De posse desse inventário, verificaremos como procedimentos sintáxicos se revestem semanticamente, de modo a produzir os efeitos de verdade e cumplicidade. Defendemos a hipótese de que as projeções enunciativas presentes no texto indicam um ponto de vista orientado pela cumplicidade entre enunciador e enunciatário, visto que se constrói a partir de uma “verdade” posta pelo enunciador sobre a qual o enunciatário é frequentemente convidado a manifestar-se; assim, a narrativa constitui-se como exemplo que justifica o posicionamento discursivo defendido pelo enunciador, ou seja, como forma de consolidar o próprio discurso.
Master data management as part of data governance: A maturity model to improve efficiency and trust in master data and thus business performance
Authors: Schmuck Matthias
Published: November 2024

An optimized master data management correlates with improved data quality, enhanced process integration and increased business agility, leading to overall better business performance. This study proposes a maturity model for structured master data management improvement that has emerged from analysing previous maturity model research, data governance, master data management and the practical experience of the researcher. The model comprises six maturity levels for eight design levels with 23 assessment factors, which are framed by six organizational factors. It extends previous maturity models by expanding organizational dimensions and considering the measurement of success across all design levels. The results serve the purpose of creating an artifact for measuring the success of master data management that is informed by data governance experience.
Peningkatan Kewaspadaan Masyarakat Kelurahan Jaticempaka, Bekasi Terhadap Banjir dengan Alat Pendeteksi Banjir
Authors: Hartanto Sri , Nurbayan  , Priyono Tri Ongko , Wiharja Ujang , Hakim Teten Dian , Slamet Purwo Santosa  , Bayu Kusumo  , Al Bahar Abdul Kodir , Naibaho Nurhabibah , Aditya Lukman
Published: November 2024

Floods occur due to rainfall that is high enough so that the water level rises above normal limits and overflows into residential areas. Floods can occur regardless of time, so there is a need to increase public awareness of floods. In the environment around the Krisnadwipayana University, namely, Jaticempaka Village, Bekasi, which is one of the public service partners, floods often occur due to the overflow of the Sunter River. Based on surveys and monitoring, the lack of public awareness of Jaticempaka Village, Bekasi, regarding flood disasters due to the lack of a system or device that can detect the high water level in the Sunter River, which causes flooding. Therefore, lecturers and students of the Electrical Engineering Study Program, Faculty of Engineering, Krisnadwipayana University were inspired to participate with carrying out public service, namely by making and installing a flood detection device that can detect water level levels at the Sunter River using an Atmega 8535 microcontroller and an ESP8266 MCU node. It is hoped that by installing the flood detection device, the public of Jaticempaka Village, Bekasi, can obtain information about the water level of the Sunter River, so that can increase public awareness of flood disasters.
Pendampingan Siswa yang Berkesulitan Belajar Matematika Materi Turunan Kelas XI MIA 2 MAN 1 Sungai Penuh
Authors: Rahayu Atika , Sari Nada Afrima , Putra Aan
Published: November 2024

Learning difficulties are a major problem in the learning process, especially in learning mathematics. This is felt by several students in class XI MIA 2 MAN 1 Sungai Penuh, where there are several students who have difficulty in understanding mathematical concepts, difficulty in acquiring the ability to read, write, or speak fluently and effectively, and limited learning time. Therefore. this mentoring aims to help individuals achieve better learning outcomes. With learning assistance, it is hoped that they can overcome the difficulties or obstacles they face in understanding the material. The mentoring method consists of three stages, namely preparation or preliminary study, implementation of mentoring and evaluation of activities. Assistance is provided to 5 students who need assistance because of their poor understanding of the material being studied. From the results of the assistance, it was found that math learning assistance greatly helped students in understanding and mastering mathematical concepts through more focused explanations and individualized support.
Do Credit Ratings Reflect Private Information about SEC Investigations?
Authors: Bonsall Samuel B. , Donovan John B. , Holzman Eric R. , Wang Xue , Yang Daniel G.
Published: November 2024

Despite private access to managers, issuer-paid credit rating agencies (CRAs) are often criticized for failing to promptly reflect material negative private information in their ratings and being ineffective corporate watchdogs. We utilize a novel dataset of private SEC investigations to examine the timeliness and informativeness of CRAs’ rating adjustments in response to material negative private information. Our evidence suggests that CRAs adjust ratings downward within a quarter following the opening of an SEC investigation. Moreover, these adjustments are over three times larger for those investigations that ultimately yield an enforcement action than for those that do not, suggesting that CRAs quickly form sophisticated expectations about the materiality of the private information. Additionally, rating downgrades during the investigations are more informative to the stock market than other rating downgrades. Overall, our evidence suggests that CRAs reduce information asymmetry in the capital markets by timely incorporating material private information in their ratings.

Data Availability: All data are available from the sources cited in the text.

JEL Classifications: D82; G24; G30; M40; M41.
Being different during treatment: a qualitative study investigating patients’ experiences of treatments for missing maxillary lateral incisors
Authors: Hedmo Cecilia , Lindsten Rune , Josefsson Eva , Ekman Aimée
Published: November 2024

Introduction and objective: Agenesis of one or more teeth is common among patients who are referred for orthodontic treatment. The most common treatments are orthodontic space closure (SC) and implant replacement (IR), which are widely studied, but the experiences of patients receiving these treatments have received little attention. The aim of this qualitative study is to explore how treatments to address missing maxillary lateral incisors (MMLIs) are experienced by individuals who are treated using either orthodontic SC or IR.
Materials and methods: This study is conducted in Sweden and based on semi-structured interviews with 13 individuals who have completed treatment, either orthodontic SC (n = 7) or IR (n = 6), to address the lack of one or two maxillary lateral incisors. Data were analysed in accordance with the grounded theory approach.
Results: Findings were classified into the main category of being different during treatment and into three associated sub-categories. The first category, that is being different due to missing teeth, refers to when a person experiences being different because of the anterior spacing The second category, that is being different due to fixed appliance, refers to when the appliance itself makes a person different. The two first categories exemplify being different in terms of appearance. The third identified category, that is being different due to treatment appointments, refers to the need to spend time differently because of having appointments at the clinic for treatment.
Conclusion: Patients MMLIs consider their treatment to start at the time of diagnosis. They experience feelings of being different irrespective of whether the type of treatment is orthodontic SC or IR. The experience of being different differs in timing and causes depending on the treatment method.
Epidemiological investigation of traumatic spinal cord injury caused by object strike in China: strategies for workplace safety improvement
Authors: Zhang Wenjie , Wang Fangyong , Chen Zezheng , Yu Yang , Liu Tao , Lei Honghui , Yin Haoran , Cheng Meiling
Published: November 2024

Objective: Being struck by an object is a major cause of traumatic spinal cord injury in China. This study aims to investigate epidemiological characteristics of spinal cord injury caused by object strike.
Methods: This research analysed data from 435 cases of strike-induced spinal cord injury from 2013 to 2022. The collected information encompassed gender, age, level of neurological injury, surgical interventions, expense, occupation, and other relevant factors. χ2tests and Mann–Whitney U test were used with a statistical significance level of 0.05.
Results: The male-to-female ratio was 11.8:1. The 30–44 age group was more likely to suffer from complete spinal cord injuries (70.5%). The predominant occupations were workers (58.9%) and farmers (15.2%). Manual labourers are usually injured in the workplace (89.4%) with a high surgical rate (95.3%).
Conclusion: Young and middle-aged males engaged in manual work constitute the primary demographic for strike-induced spinal cord injury. Safety education in workplaces such as construction sites and mines should be emphasized to reduce the occurrence of spinal cord injuries caused by object strikes.
PROGRAMA DE AQUISIÇÃO DE ALIMENTOS (PAA) EM PIAÇABUÇU-AL: UMA ANÁLISE DA ATUAÇÃO DO PROGRAMA NO CONTEXTO DO MUNICÍPIO
Authors: Santos Janayson Rodrigues dos , Ferraz José Maria Gusman , Stoffel Janete , Silva Sanielma Lessa da
Published: November 2024

Como política pública, o PAA tornou-se um dos principais instrumentos do Estado brasileiro com foco no incentivo a produção da agricultura familiar por meio de um canal de comercialização exclusivo para este segmento. Assim, esta pesquisa tem como objetivo traçar um breve panorama da atuação do PAA no município de Piaçabuçu-AL. Esta pesquisa utilizou como referência o PAA modalidade doação da CONAB. A atuação do PAA ganha importância quando se analisa o contexto sócio econômico de Piaçabu-Al, com alto índice de pobreza, baixo PIB per capita e IDH, e segundo o IBGE (2024) somente 7,75% da população está ocupada com emprego formal. A pesquisa está caracterizada como um estudo descritivo e exploratório, apresentando uma abordagem qualitativa. Também foi realizado um levantamento bibliográfico sobre as temáticas políticas públicas e PAA, além da coleta de dados secundários em sites oficiais como: IBGE, CONAB, Portal da Transparência, Ministério da Cidadania etc. A pesquisa demonstrou que mesmo não tendo uma atuação efetiva em todos os anos de sua vigência, a atuação do PAA tornou-se de grande relevância no município Piaçabuçu-Al dentro de seu contexto sócio econômico, principalmente por proporcionar geração de trabalho e renda. Sendo que no ano de 2023 o programa contemplou 70 agricultores familiares do município. Neste sentido, compreende-se que uma ampliação da atuação do PAA por parte do Estado brasileiro, pode se tornar uma ferramenta no combate à pobreza dentro do espaço rural, por estimular cadeias produtivas do segmento da agricultura familiar com trabalho e renda.
ANALYSIS OF THE EFFECTIVENESS OF THE ONLINE REGISTRATION SYSTEM ON PATIENT SATISFACTION AT RATU AJI PUTRI BOTUNG HOSPITAL, PENAJAM PASER UTARA REGENCY
Authors: Hadisaputro Elvin Leander , Hasrullah Hasrullah , Setyaningsih Erlin , Wahyuni Nuorma
Published: November 2024

This study aims to analyze the effectiveness of the online registration system on patient satisfaction at Ratu Aji Putri Botung Hospital, Penajam Paser Utara Regency. This research uses a quantitative approach. The subjects of this study were patients of Ratu Aji Putri Botung Hospital and a sample of 83 people was taken as respondents. The data collection method used a questionnaire. The testing technique uses validity test, reliability test, classical assumption test and Regression Analysis test in which there are t test results, and the coefficient of determination. Based on the results of the t test regression analysis, it shows that the tcount value on the Online Registration System variable (X) on Patient Satisfaction (Y) is 5.775 and the significance value is 0.000. Then the significance value of 0.000 <0.05, while the comparison between tcount and ttable is 5.775> 1.989. This shows that the level of significance is smaller and also the comparison between tcount is greater than ttabel and is positive, it can be concluded that the Online Registration System (X) has a positive and significant effect on Patient Satisfaction (Y). The results showed that the utilization of information and communication technology applied to this Online Registration System will create an organized system and avoid the accumulation of more patients to come repeatedly to the service place, but customers only come according to the days and hours obtained from the Online Registration System website patients at a service place, so that the online registration system will increase patient satisfaction at Ratu Aji Putri Botung Hospital.
THE INFLUENCE OF ORGANIZATIONAL CULTURE, WORK MOTIVATION, AND COMPETENCE ON EMPLOYEE PERFORMANCE AT XYZ STORE IN BATAM
Authors: Junianto Pilifus
Published: November 2024

This research examines the influence of organizational culture, work motivation, and competence on employee performance at XYZ Store in Batam. Since 2004, XYZ Store has operated a stationery retail business unit and has expanded into eight branches, which are currently distributed across Batam City. The sampling method employed was purposive sampling. Data collection was conducted using a questionnaire distributed to 71 employees at XYZ Store. The research findings indicate that organizational culture has a significant impact on the performance of XYZ Store employees; work motivation significantly influences the performance of XYZ Store employees; competence has a significant effect on the performance of XYZ Store employees; and simultaneously, the three variables have a positive and significant effect on the performance of XYZ Store employees, with R2 is 0.911, which indicating that the independent variables has influenced 91.1% to dependent variable. The remaining 8.9% is influenced by other factors that were not examined in this study.
ГЕОМЕТРИЗИРОВАННАЯ ФИЗИКА ВАКУУМА. ЧАСТЬ 8: ИНЕРЦИОННЫЙ ЭЛЕКТРОМАГНЕТИЗМ ДВИЖУЩИХСЯ «ЧАСТИЦ»
Authors: БатановГаухман Михаил
Published: November 2024

Данная статья является восьмой частью научного проекта под общим названием «Геометризированная физика вакуума на основе Алгебры сигнатур» [1,2,3,4,5,6,7]. В этой статье предложены метрико-динамические модели движущихся «электрона» и «позитрона», которые перемещаются с прямолинейно и равноного (т.е. с постоянной скоростью) относительно вакуума, стабильными искривлениями которого они сами являются. Показано, что полученные результаты применимы для всех «барионов» и «мезонов», входящих в состав Стандартной модели элементарных частиц. Модельные представления о наведении тороидально-винтовых вихрей вокруг направления движения «частиц» и «античастиц» позволили дать полностью геометризированные объяснение таких явлений как движение атомистических тел по инерции (без привлечения понятия масса), инерционный электрический ток и инерционное электромагнитное поле. Как и весь проект, данное исследование направлено на частичную реализацию программы полной геометризации физики Клиффорда-Эйнштейна-Уилера.
Динамика генеалогической структуры популяции молочного скота Омской области
Authors: Юрченко Елена
Published: November 2024

При анализе динамики поголовья по принадлежности к одной определенной линии можно сделать вывод, что по линии Вис Бэк Айдиал можно отметить снижение процентного отношения с 58,6 % в 2019 году до 38,8 % в 2022 году, но к 2023 году доля скота этой линии вновь увеличивается и составляет уже 54,4 %. По линии Рефлекшн Соверинг динамика обратная, с 2019 года по 2022 год отмечается рост доли поголовья, отнесенного к этой линии с 30,4 % до 45,4 %, а в 2023 году снижается и составляет чуть более 1/3 от всего оцененного поголовья (34,4 %). Максимальная доля животных, отнесённых в линии Монтвик Чифтейн, отмечена в 2022 году – 15,4 %, а минимальная – в 2023 году – 6,0 %. Доля животных линии Силинг Трайджун Рокит, как отмечалось ранее, была самая незначительная на протяжении всего исследуемого периода, при этом необходимо отметить, что начиная с 2019 года по 2022 год она снизилась более чем на треть и составила всего 0,3 %, но в 2023 году доля животных данной линии среди всего исследуемого поголовья значительно возросла и составила 5,2 %, это произошло в основном за счет сокращения к 2023 году поголовья животных линии Монтвик Чифтейн. К линии Пабст Говернер отнесено лишь 0,02 % исследуемого поголовья в 2019 году, далее животных этой линии в стадах не отмечено.
Specifics of constructed dialogue use in motivational discourse
Authors: Khoutyz I.P.
Published: November 2024

The article examines the use of constructed dialogue (CD) in motivational discourse. The aim of the research is to identify the specifics of the CD use in three motivational speeches in Russian. Thus, three speeches by Radislav Gandapas, Vyacheslav Polunin and Margulan Seisembaev were determined as motivational and included into the research corpus. Motivational discourse is chosen for the analysis due to its increasing importance in everyday life and its power to influence individual's world view formation. Strong addressee-orientation, expressiveness and emotionality are recognized as the main characteristics of motivational discourse. With the help of the linguistic-pragmatic analysis, which implied the use of contextual analysis and methods of classification, systematization and interpretation, it was determined that CD is an integral feature of motivational speech. The frequency of its use is not connected with expressivity and emotionality. However, it is aimed at establishing the contact with the audience and clear explanation of notions connected with the topic of the speech. Emotional speakers, relying actively on nonverbal and paraverbal communication, prefer such types of CD as dialogue as inner speech and choral. It seems that the dialogue as instantiation type prevails in more restrained from emotions motivational speech that draws on arguments, comparisons and citations.
Increasing library presence on social media with content strategy: tools and suggestions
Authors: Duong Thi Phuong Chi
Published: November 2024

Social media is a great way to connect with organization's audience and have a two-way conversation. Nowadays, librarians are becoming increasingly interested in applying social media to better understand the needs of readers as well as promote library resources and services. Therefore, content strategy is considered as a valuable tool for planning to update content of all library communication platforms on social media. This article aims to lay out some of the fundamental tools used by content strategists and discusses how librarians can apply them to their own content. The study would facilitate librarians to understand and develop a content strategy which increases library presence on social media.
Increased sense Review of the book: Increasing sense, a collection of scientific articles, dedicated to the anniversary of Tatyana Viktorovna Shmeleva, ed. by A.N. Speranskaya, Moscow, RUSAINS publ., 2021, 320 p.
Authors: Norman B.Ju.
Published: November 2024

The article presents a review of a collection of articles written by colleagues and students of T.V. Shmeleva, the outstanding Russian linguist. The articles of the collection continue and develop the problems raised in the Shmeleva's works: syntax, speech genres, onomastics, speech culture, media linguistics, key words of the current moment, etc.
OPTIMASI DAN VALIDASI METODE KLT-DENSITOMETRI FASE TERBALIK UNTUK ANALISIS OKSIBENZON DALAM LOSION TABIR SURYA
Authors: Andayani Regina , Andira Retno Permata , Armin Fithriani
Published: November 2024

AbstractSunscreen is useful for protecting the skin against sun exposure.  Oxybenzone is one of the active ingredients in sunscreen which can cause skin allergies, redness, dryness, and acne. This study aims to optimize and validate the reverse phase densitometry thin layer chromatography (TLC) method for the analysis of oxybenzone in sunscreen lotions. The TLC silica gel 60 RP-18 F254 was used as the stationary phase, the mobile phase was acetonitrile: aquabidest (18:3). The Rf values of oxybenzone in lotion A and B were 0.63. The resolution of oxybenzone in lotions A and B were 2.53 and 3.2, respectively. The correlation coefficient (r) of oxybenzone was 0.999 in the range of 50 – 250 μg/mL, the limit of detection was 16.37 μg/mL and the limit of quantitation was 49.39 μg/mL. The precision of lotions A and B was ≤ 2%. The % recovery of oxybenzone in lotion A and lotion B was  99.33-99.63%. The results showed that the levels of oxybenzone lotion A and B were 3.4% and 2.59% successively.  The reverse phase TLC-Densitometry method is a valid method for the analysis of oxybenzone in sunscreen lotions.Keywords: Oxybenzone, sunscreen, validation, thin layer chromatography-densitometry, reversed-phase. OPTIMASI DAN VALIDASI METODE KLT-DENSITOMETRI FASE TERBALIK UNTUK ANALISIS OKSIBENZON DALAM LOSION TABIR SURYA Abstrak Tabir surya berguna untuk melindungi kulit dari paparan sinar matahari. Oxybenzone merupakan salah satu bahan aktif tabir surya yang dapat menyebabkan alergi kulit, kemerahan, kering dan berjerawat. Penelitian ini bertujuan untuk mengoptimalkan dan memvalidasi metode kromatografi lapis tipis (KLT) densitometri fase terbalik untuk analisis oksibenzon dalam lotion tabir surya. Silika gel TLC 60 RP-18 F254 digunakan sebagai fase diam, fase geraknya adalah asetonitril: akuabides (18:3). Nilai Rf oxybenzone pada lotion A dan B adalah 0,63. Resolusi oxybenzone pada lotion A dan B berturut-turut adalah 2,53 dan 3,2. Koefisien korelasi (r) oxybenzone adalah 0,999 dalam kisaran 50 – 250 μg/mL, batas deteksi adalah 16,37 μg/mL dan batas kuantitasi adalah 49,39 μg/mL. Nilai presisis lotion A dan lotion B adalah ≤ 2%. Persentase perolehan kembali oxybenzone pada lotion A dan lotion B adalah 99,33-99,63%. Hasil penelitian menunjukkan bahwa kadar oxybenzone lotion A dan B berturut-turut adalah 3,4% dan 2,59%. Metode TLC-Densitometry fase terbalik adalah metode yang valid untuk analisis oxybenzone dalam lotion tabir surya.Kata kunci: Oxybenzone, tabir surya, validasi, kromatografi lapis tipis-densitometri, fase terbalik.
Formulasi dan Karakterisasi Nanopartikel Supernatan Bacillus subtilis dengan Poly Lactic-co-Glycolic Acid (PLGA)
Authors: Kurniawan Dhadhang Wahyu , Farahnida Alfia Nayudia , Sulaeman Uyi
Published: November 2024

Pemanfaatan supernatan Bacillus subtilis kini telah banyak dimanfaatkan dalam bidang kesehatan sebagai probiotik karena mengandung senyawa bakteriosin serta enzim enzim. Senyawa tersebut mampu menghambat mikroorganisme lain dan mudah terdegradasi oleh enzim proteolitik. Pemanfaatan nanopartikel polimer cukup efektif untuk melindungi probiotik dari kondisi gastrointestinal. Penelitian ini bertujuan untuk membuat sediaan nanopartikel supernatan B. subtilis dengan pembawa PLGA dan dilakukan karakterisasi. Nanopartikel dibuat dengan metode solvent evaporation menggunakan variasi konsentrasi PLGA. Hasil karakterisasi nanopartikel supernatan B. subtilis memiliki ukuran nanopartikel 545,45 ± 90,73 nm dengan nilai indeks polidispersitas (PDI) kategori monodisperisi yaitu 0,503 ± 0,065 dan zeta potensial -14,57 ± 3,08 mV. Morfologi yang dihasilkan berbentuk sferis dan cukup seragam. Analisis Fourier transform infrared spectroscopy (FTIR) menunjukkan pita-pita spektrum mirip dengan nanopartikel PLGA dan menunjukkan beberapa puncak spesifik supernatan B. subtilis dengan sedikit pergeseran. Analisis Differential Scanning Calorimetry (DSC) pada termogram tidak menunjukkan adanya puncak endotermik dari supernatan B. subtilis. Formulasi nanopartikel supernatan B. subtilis telah ter-loading-kan ke dalam sistem nanopartikel melalui analisis FTIR dan DSC.
Studi In Silico Senyawa 5-BOTP dan ADPB sebagai Senyawa Pembawa Radioteranostik terhadap LAT-1
Authors: Holik Holis Abdul , Elaine Angela Alysia , Sitinjak Bernap Dwi Putra , Qolbina Shofura Marsa , Ibrahim Faisal Maulana , Achmad Arifudin , Sudarmanto B.S. Ari , Kartamihardja Achmad Hussein Sundawa
Published: November 2024

Kompleksitas patogenesis kanker membuat kanker sulit untuk menemukan target terapi yang tepat, sehingga tingkat keberhasilan obat baru dalam uji klinis rendah. Oleh karena itu, studi pengembangan teknik intervensi yang baru untuk pasien kanker sangat penting. Large-type Amino Acid Transporter 1 (LAT-1) diekspresikan secara berlebihan dalam sel kanker jika dibandingkan dengan sel normal, hal ini menjadikannya salah satu target molekuler khusus untuk terapi kanker. Fungsi LAT-1 adalah memberikan nutrisi pada sel kanker untuk berkembang biak secara masif sehingga penghambatan LAT-1 dapat dijadikan alternatif terapi kanker. Penelitian ini bertujuan untuk mendapatkan senyawa potensial yang akan digunakan untuk radioteranostik dengan dua senyawa inhibitor LAT-1 sebagai senyawa pembawa, yaitu 5-Benzyloxytryptophan (5-BOTP) dan asam (S)-2-amino-4-(3,5-diklorofenil) butanoat (ADPB) yang dikonjugasikan dengan senyawa linker dan berbagai agen pengkelat bifungsional (BFCA) terhadap situs antiporter LAT-1. Metode penelitian terdiri dari mode pengikatan senyawa 5-BOTP dan ADPB terkonjugasi dengan LAT-1, simulasi penambatan molekuler, dan analis pre-ADMET. Hasil penelitian menunjukkan bahwa 5-BOTP-6AHA-H2CB-DO2A dan ADPB-6AHA-H2CB-DO2A memiliki afinitas terbaik dan kompleks pengikatan yang terbaik dengan LAT-1 sehingga keduanya berpotensi sebagai agen radioteranostik kanker dengan menghambat LAT-1.Kata kunci: Kanker, radioteranostik, LAT-1, 5-Benzyloxytryptophan, asam (S)-2-amino-4-(3,5-diklorofenol) butanoat.
Islamic Law and Gender Equality: Challenges and Reforms in Sri Lanka’s Muslim Marriage and Divorce Act
Authors: Dawood Shamila
Published: November 2024

This article examines the ongoing debates and reform efforts surrounding the Muslim Marriage and Divorce Act of 1951 (MMDA) in Sri Lanka. The Act has faced substantial criticism for its inability to adapt to the evolving needs of modern society, often prioritizing men’s interests over women’s rights. Despite numerous reform attempts, reaching a consensus on crucial provisions has proven challenging, creating significant obstacles to amending the MMDA. Employing library research, this article analyzes reports from various committees to assess current practices, which reveal conflicting perspectives between committees and civil society organizations. This study re-evaluates the MMDA’s provisions to determine whether proposed reforms align with Sharia law while meeting international legal standards, particularly Sri Lanka’s obligations to eliminate all forms of discrimination against women, while considering religious and cultural sensitivities. The article underscores the need for collaborative dialogue among stakeholders to foster reforms that address the evolving Muslim community’s legal needs, focusing on justice and equality.
[Artikel ini mengkaji perdebatan yang sedang berlangsung dan upaya reformasi seputar Undang-Undang Perkawinan dan Perceraian Muslim tahun 1951 di Sri Lanka. Undang-undang tersebut telah menghadapi kritik besar karena gagal beradaptasi dengan kebutuhan masyarakat modern yang terus berkembang, yang sering kali memprioritaskan kepentingan laki-laki di atas hak-hak perempuan. Meskipun ada banyak upaya reformasi, mencapai konsensus tentang ketentuan-ketentuan utama telah terbukti menantang, menciptakan hambatan signifikan terhadap amandemennya. Dengan menggunakan penelitian kepustakaan, artikel ini menganalisis laporan dari berbagai komite untuk menilai praktik terkini, di mana terdapat pandangan yang saling bertentangan antara komite dan organisasi masyarakat sipil. Studi ini mengevaluasi kembali ketentuan-ketentuan tersebut untuk menilai apakah reformasi yang diusulkan selaras dengan hukum Syariah sekaligus memenuhi standar hukum internasional, khususnya kewajiban Sri Lanka untuk menghapuskan segala bentuk diskriminasi terhadap perempuan, sambil mempertimbangkan kepekaan agama dan budaya. Artikel ini menggarisbawahi perlunya dialog kolaboratif di antara para pemangku kepentingan untuk mendorong reformasi yang memenuhi kebutuhan hukum komunitas Muslim yang terus berkembang dengan menekankan keadilan dan kesetaraan.]
Breaking the habit: The impact of tobacco taxation on smoking behavior
Authors: O’Neill Alexandra , Marques Mariana
Published: November 2024

Objective: This study investigates the influence of tobacco prices on consumption habits among 200 smokers in Lisbon, Portugal, focusing on generational preferences and perceptions of tobacco taxes. Methods: A cross-sectional survey was conducted using a quantitative approach. Participants were categorized by generational cohort, and data on tobacco consumption types, awareness of tobacco taxes, and opinions on tax increases were collected. Statistical analyses were used to explore relationships and predictors. Results: Findings reveal that 46.5% of participants favored heated tobacco, 37.0% smoked cigarettes, and 16.5% consumed other types like roll-your-own tobacco and electronic cigarettes. Significant generational differences were observed, with older cohorts predominantly smoking cigarettes (51.5%), while Generation Z showed a preference for heated tobacco (55.2%). Most smokers (79.5%) were aware of tobacco taxes, with diverse opinions on their purpose: revenue generation (44.0%), consumption reduction (44.5%), and indifference (11.5%). Despite this awareness, 60.5% reported no change in consumption habits due to tax increases. Conclusion: The study underscores the complexity of tobacco consumption behaviors influenced by price and generational factors. While heated tobacco gains popularity among younger smokers, traditional cigarettes remain prevalent among older cohorts. The findings highlight challenges in tobacco control policies, suggesting a need for comprehensive strategies integrating price measures with targeted educational and cessation interventions to effectively reduce tobacco use across different generations.
Kirschner wire creates more microdamage than standard or acrylic drill bits in the rabbit (Oryctolagus cuniculi) femur
Authors: Massie Anna M. , Kapatkin Amy S. , Garcia Tanya C. , Marcellin-Little Denis J. , Guzman David Sanchez-Migallon , Chou Po-Yen , Stover Susan M.
Published: November 2024

OBJECTIVE

Histologically evaluate damage to rabbit femur after the creation of bicortical 1.5-mm-diameter holes using a standard surgical drill bit, an acrylic drill bit, and a Kirschner wire (K-wire).

METHODS

10 femora (5 pairs) from skeletally mature female intact New Zealand white rabbits were used. The bone diaphyses were divided into 4 locations, systematically undergoing each test (surgical drill bit, acrylic drill bit, K-wire, and intact control). Four pairs were drilled using a mechanical testing machine, and 1 pair was drilled by hand. Cross-sections of the bone were stained en bloc with basic fuchsin for undecalcified histological evaluation. Damaged bone was reported as a percentage of a standardized area and categorized by location (cis- or transcortex), drill contact (entrance or exit of the cortex), and total damage (both cortices).

RESULTS

The drilling method (hand vs mechanical testing machine) had no effect on histologic damage, so results were analyzed by combining all data. The K-wire demonstrated the greatest area of cracks/damage compared to both standard surgical and acrylic drill bits, whereas no difference in damage was noted between the 2 drill bits for all variables.

CONCLUSIONS

The K-wire and drill bits caused microdamage; K-wire drilling created more microdamage than drill bits.

CLINICAL RELEVANCE

The rabbit bone cortex is thin and brittle relative to dogs and cats, leading to failure during and after fracture fixation. The clinical failure of rabbit bone is at least partially caused by drill bits or K-wires causing microcracks.
Class: A Memoir of Motherhood, Hunger, and Higher Education
Authors: Dadzie Benjamin Michael
Published: November 2024

Book review of Stephanie Land's Class: A Memoir of Motherhood, Hunger, and Higher Education by Benjamin Michael Dadzie from Clemson University.
Mujer, cuerpo y territorio: construcción de paces y resistencias con el Movimiento Ruta Pacífica de las Mujeres - Eje Cafetero. Experiencia de la práctica profesional realizada en el periodo 2019-1
Authors: Perdomo Celis Laura María
Published: November 2024

En el presente artículo encontrarán la descripción de la práctica profesional de una estudiante del Programa de Psicología de la Universidad Surcolombiana de Neiva-Huila en intercambio con la Universidad Católica de Pereira y el Movimiento Ruta Pacífica de las Mujeres Regional Eje Cafetero en el período 2019-1. El desarrollo de esta se llevó a cabo a partir de dos ejes, acciones públicas/actos simbólicos y de acompañamiento psicosocial, que se abordaron metodológicamente desde metodologías feminista y de la educación popular. La apuesta teórica desde la que se desarrolla son los feminismos, la sororidad, los derechos sexuales y reproductivos, las violencias basadas en género y la psicología social comunitaria. Además, a partir de una reflexión frente al quehacer de la psicología social y el feminismo, se presentan las conclusiones a las que, tanto colectiva como individualmente, se llega.
Representaciones sociales sobre subjetividad, inmersas en las prácticas pedagógicas de estudiantes con capacidades diversas
Authors: Vanegas López Julián Alberto , Castillo Caycedo Angie Katherine , Cuellar Urriago Fabián Fernando , Vargas Bahamón Alicia Fernanda
Published: November 2024

En Neiva actualmente existen centros educativos que realizan programas de inclusión con niños, niñas y adolescentes en condición de discapacidad, pero, además de la normatividad existente es necesario conocer cuáles son las representaciones sociales de sujeto que están inmersas en las prácticas pedagógicas de los docentes dentro del aula. Además, es pertinente interrogar por la subjetividad, cuando las personas con capacidades diversas son reducidas a una condición biologicista y se dejan de potenciar otras dimensiones de su desarrollo. La pregunta de investigación que se propone cómo objetivo responder es ¿Cuáles son las representaciones sociales de los docentes de una Institución Educativa de la ciudad de Neiva acerca de la subjetividad en sus estudiantes con capacidades diversas? El análisis de los datos se realizó mediante las categorías de creencias y prácticas, la búsqueda de estas categorías se efectuó en la agrupación de patrones comunes expresados en los relatos de los docentes. Los resultados revelan tres hipótesis centrales: necesidad de control, desconocer su sexualidad y sin identidad. Se concluyó que la intervención pedagógica de los docentes apunta a la necesidad de control sobre el comportamiento de los estudiantes con capacidades diversas, lo que se convierte en un desconocimiento de su subjetividad en términos de negar su sexualidad y de no contar con una identidad que los represente ante el mundo.
Pendampingan Penerapan Pajak Parkir dalam rangka Peningkatan Pendapatan Asli Daerah (PAD) Pemerintah Kabupaten Badung
Authors: Putri Kadek Gita Jesiska , Putri Putu Indah Dianti
Published: November 2024

Kegiatan pengabdian masyarakat ini bertujuan untuk mendampingi penerapan penetapan wajib pajak parkir di Kabupaten Badung sebagai upaya optimalisasi Pendapatan Asli Daerah (PAD). Melalui tiga tahapan utama yang meliputi observasi, pelaksanaan pendampingan, dan evaluasi, dilakukan penataan terhadap proses pemeriksaan pajak, konsultasi, negosiasi, hingga pelaporan pajak parkir. Hasil kegiatan menunjukkan peningkatan efisiensi waktu pemeriksaan, ketepatan pembayaran, serta kepatuhan wajib pajak dalam melaksanakan kewajiban mereka. Kesadaran wajib pajak terhadap tanggung jawab perpajakan juga meningkat secara signifikan. Pendekatan ini berhasil mengoptimalkan potensi PAD dari pajak parkir dan memberikan kontribusi positif terhadap pengelolaan pajak di Badung.
Pelatihan Cleanlinnes, Health, Safety & Environmental Sustainability (CHSE) di Rumah Sakit Bhayangkara Tk. III Indramayu
Authors: Chandra Teddy , Riyadi Heru , Prabowo Susilo Dwi , Sosiadi Rohyan , Wibowo Sukarno
Published: November 2024

Since early in 2020, the Covid-19 pandemic has arrive in our home land. Many people get infected by this virus. The goverment take a quick and responsive restrictive, preventive and currative policy to mitigate this disaster. The social life has change. So many people normal habits has to be adjusted to the situation. Many healthy protocol was applied by the goverment to eradicate this global pandemic desease. CHSE was one of the healthy life style promoted by the goverment c.q Ministry Of Tourism Creative Economy. CHSE was the protocol to implementing the cleanlinnes, health, safety environmental sustainability. the purpose of this CHSE training was to create a healthier and condusive condition for the people, so they can still do the activity during the pandemic situation. Sejak awal tahun 2020 Pandemi Covid-19 datang melanda tanah air. Banyak di antara masyarakat Indonesia yang terjangkit virus corona ini. Pemerintah bergerak cepat dalam upaya mitigasi bencana virus ini dengan mengeluarkan berbagai kebijakan publik yang bersifat restriktif, preventif dan kuratif agar penyebarannya dapat ditekan. Hal itu berdampak kepada kehidupan masyarakat Indonesia. Kebiasaan-kebiasaan normal yang seringkali masyarakat lakukan, kini telah berubah. Berbagai pembatasan-pembatasan dan juga protokol kesehatan diterapkan oleh pihak berwenang dalam upaya untuk menanggulangi wabah global ini. Diantara beberapa kampanye gaya hidup sehat yang digaungkan pemerintah itu, salah satunya adalah kampanye Cleanlinnes, Health, Safety Environmental Sustainability (CHSE) yang digalakkan oleh kementerian pariwisata ekonomi kreatif. CHSE adalah suatu protokol kesehatan yang menekankan kepada terjaganya kebersihan (cleanlinnes), upaya menjaga kesehatan (health), upaya menjaga keamanan (safety) dan juga upaya menjaga kelestarian lingkungan (environmental sustainability). Tujuan dari pelatihan CHSE adalah agar terwujud suatu keadaan yang kondusif dalam menjalankan aktifitas di tengah pandemi yang belum diketahui kapan akan berakhirnya.
Comparative Research on Landing and Rollout Characteristics of Skid-Equipped and Wheeled Aircraft
Authors: Liang Taotao , Yin Yin , Yin Qiaozhi , Nie Hong , Wei Xiaohui
Published: November 2024

Skid landing gear is a specialized landing device known for its compact structure and lightweight. However, current research on the dynamic characteristics of skid-equipped aircraft on concrete runways is limited, which raises uncertainties about its practical applications. To address this gap, a general aircraft model based on a modular concept is first constructed, considering the coupling effects of aerodynamic, buffer, and ground forces. On this basis, the differences in motion characteristics between skid-equipped and wheeled aircraft are compared in detail. Then, the impact of various factors on the landing characteristics of skid-equipped aircraft is analyzed, such as initial longitudinal velocity, pitching angle, and friction coefficient of skid. Simulation results show that the lack of buffering capability provided by tires results in a [Formula: see text] increase in overload for skid-equipped aircraft and a [Formula: see text] decrease in the efficiency of the main landing gear buffer. Notably, the initial pitching angle has a critical impact on the landing overload of skid-equipped aircraft. Due to the significant differences in the mechanical properties of the landing gears, the skid-equipped aircraft without nose wheel steering ability is a statically unstable system during the rollout phase. The intervention of asymmetric disturbances would pose a serious threat to the rollout safety.
Surfactant-Polymer Slug Optimization, Injection Rate & Pattern Size Determination Using The Cmg Simulator In The Mj Well
Authors: Gaspar Fonseca Oliveira  , Gama Luz Sousa  , Zafran Syahyuda  , Mario Abel Carvalho
Published: November 2024

The MJ well is one of the oldest in the Central Sumatra field. This field was originally produced in 1952, with a reserve of 4.5 MMSTB. This explains why EOR studies are needed to increase the production of oil.
The MJ well can be injected with surfactant-polymer based on the EOR screening criteria. Surfactant performance mechanisms can minimise IFT and displacement, however, polymers can limit mobility by increasing the viscosity of formation water and sweep efficiency. It is preferable to use reservoir modelling before applying surfactant-polymer to a well. Surfactant-polymer simulation, specifically CMG software, is used in this research. Several simulations were run using sensitivity such as slug SP, injection rate, and pattern size to determine the best approach for use in the MJ well. Surfactant injection was performed after a year of applying a water flood followed by injection of surfactant-polymer with several slug variations, namely 0.2 PV, 0.3 PV, 0.4 PV, 0.5 PV, and 0.6 PV at varied injection rates. 1600 BPD, 2300 BPD, and 3000 BPD, as well as many well-pattern variations, including a 5-spot pattern, a 7-spot pattern, and a 9-spot pattern.
Based on the simulation, optimal results are obtained at a slug of 0.6 PV, an injection rate of 3000 BPD, and a 5-Spot well pattern with a total amount of oil of 2,023,700 bbl and a recovery factor of 81.67%.
Exploration of the Molecular and Phylogenetic Aspects of Brucella intermedia (Ochrobactrum intermedia)
Authors: Zeadan Ayat Majeed , Abbas Sura Mouaid , Mahal Shaimaa Noori , Taher Noor M.
Published: November 2024

Brucella bacteria are among the oldest known zoonotic pathogens and they have become iconic case studies in infectious diseases. Genome comparisons have led to the reclassification of the genus Ochrobactrum, with its individual species now being categorized as Brucella. This study aims to isolate and molecularly identify Ochrobactrum intermedia from Iraqi patients. One hundred seventy urine samples were collected from patients with various conditions suspected of brucellosis. Based on identification by the VITEK compact system, two of the bacterial isolates were identified as Brucella intermedia (Ochrobactrum intermedia) species. This was confirmed by polymerase chain reaction using genus-specific primers for the 16S rRNA and recA genes which are specific for B.intermedia. The 16S rRNA gene sequences were aligned using BLAST and the BioEdit program. It was observed that there was a remarkable 99% similarity among the Brucella intermedia sequences. The affiliation of the two novel strains of B. intermedia, identified as Brucella intermedia strain BC-TCC 16S ribosomal RNA gene (OP415407) and Brucella intermedia strain Baghdadies 16S ribosomal RNA gene (OP415409), was confirmed through the analysis of both 16S rRNA and recA genes. These findings suggest that the use of 16S RC-PCR and sequencing in clinical settings can improve patient care by increasing the sensitivity of detection and identification of bacterial pathogens, resulting in more diagnoses of bacterial infections. By studying novel strains in a phylogenetic tree, researchers can learn more about the diversity of a species and can identify potential new threats to human and animal health.