bluuebunny/crossref_metadata_2025 huggingface dataset:
Emotional states and self-confidence independently fluctuate at different time scales
Authors: da Fonseca María , Maffei Giovanni , Bote Rubén Moreno , Hyafil Alexandre
Published: August 2021

Emotional states are an important ingredient of decision-making. Human beings are immersed into a sea of emotions where episodes of high mood alternate with episodes of low mood. While changes in mood are well characterized, little is known about how these fluctuations interact with metacognition, and in particular with our perception of having made the right choice. Here, we evaluate how implicit measurements of confidence are related with the emotional states of human participants through two online longitudinal experiments involving mood self-reports and visual discrimination decision-making tasks. Self-confidence was assessed on each session by monitoring the proportion of opt-out trials when an opt-out option was available, as well as the mean reaction times on standard correct trials. We first report a strong coupling between the mood, stress, food enjoyment and quality of sleep reported by participants in the same session. Second, we confirmed that the proportion of opt-out responses as well as reaction times in non-opt-out trials provided reliable indices of self-confidence in each session. We introduce a normative measure of overconfidence based on the pattern of opt-out selection and the signal-detection-theory framework. Finally and crucially, we found that mood, sleep quality, food enjoyment and stress level are not coupled with self-confidence, but rather they fluctuate at different time scales: emotional states expose faster fluctuations (over one day or half-a-day) than self-confidence level (two-and-a-half days). Therefore, our findings suggest that emotional states and confidence in decision making spontaneously fluctuate in an independent manner in the healthy adult population.
Expectations about plant edibility in 6-month-old infants (Rioux & Wertz)
Authors: rioux camille , Wertz Annie E.
Published: August 2021

Learning what to eat is not easy. Here we examined 6-month-olds’ expectations about what kinds of entities are likely to be edible using a violation-of-expectation setup in which infants viewed an actor eating parts of two different items. In Experiment 1 (N=40, 20 females), infants expected plants, relative to feature-matched artifacts, to be edible, replicating a previous finding. In Experiment 2 (N=40, 23 females), infants tended to differentially expect fruits to be edible, but not leaves. However, infants’ expectations about fruits presented on their own were attenuated relative to their expectations for whole plants. These findings suggest that there is selectivity in infants' edibility inferences and the kinds of resources prioritized in human diets have shaped infants’ food learning.
The Association Between Well-Being and Objectively Measured Versus Self-Reported Smartphone Time
Authors: Walsh Lisa C. , Okabe-Miyamoto Karynna , Regan Annie , Twenge Jean , Lyubomirsky Sonja
Published: August 2021

Recent correlational research links smartphone and social media use to lower well-being among Gen Z youth, yet other work suggests that the effects are small and unnoteworthy. However, these findings rely heavily on self-report. How accurate is self-reported smartphone time and are objectively measured screen activities associated with lower well-being than nonscreen activities? Finally, are some smartphone uses “better” for well-being than others? We addressed these questions by examining correlations among psychosocial well-being and smartphone time in 414 Gen Z participants. Although objective smartphone use (i.e., assessed via Apple’s Screen Time function) and self-reports were correlated at r=.55, most participants were unable to accurately estimate their smartphone time. Furthermore, the more they used their smartphones—whether assessed objectively or via self-report—the less happy they were (rs=–.14 to .17). However, some apps were associated with more well-being (e.g., Camera, News, Snapchat) and others with less (e.g., Facebook, Reddit, Tinder, Twitter).
Estimation of Solar Energy Using Different Empirical Models at Mid Hill, Nepal
Authors: Joshi U. , Shrestha P. M. , Maharjan S. , Maharjan B. , Chapagain N. P. , Karki I. B. , Poudyal K. N.
Published: August 2021

Accurate knowledge of global solar radiation distribution is essential for designing, sizing, and performing an evaluation of solar energy system in any part of the world. However, it is not available in many sites of Nepal due to the high expense of the technical process. This study is focused on the performance of different models based on daily global solar radiation, sunshine hour, temperature, and relative humidity at mid-hill region Lumle, (lat. 28.29650N, long. 83.8179oE, and Alt. 1740.0 m.a.s.l.). This study is carried for the year 2018 to 2020. The performance of different models based on sunshine hour, temperature, and relative humidity were analyzed using the regression technique and statistical tools such as Root Mean Square Error (RMSE), Mean Bias Error (MBE), Mean Percentage Error (MPE), and Coefficient of determination (R2). After the analysis, the modified Angstrom model (M-9) based on temperature difference and relative humidity was found to be the best in terms of accuracy of least RMSE value and highest coefficient of determination. Finally, the empirical constants for model m-9 are a = 0.003, b = 0.523, c = 0.118 and, d = 0.002 obtained. The calculated empirical constants can be utilized for the prediction of GSR at similar geographical locations of Nepal.
Determination of Optical Constants and Thickness of Nanostructured ZnO Film by Spin Coating Technique
Authors: Ghimire R. R. , Dahal Y. P. , Rai K. B. , Gupta S. P.
Published: August 2021

In this report, we have investigated optical constants and thickness of nanostructured ZnO films grown on a glass substrate by sol-gel spin coating technique using zinc acetate as precursor. Optical constants such as complex refractive index ñ and dielectric constant ϵ determined from the transmittance spectrum in the ultraviolet, visible, near infrared (UV-VIS, NIR) region by envelope method. The value of refractive index decreases from 2.34 to 1.86 and extinction coefficient increases from 0.28 to 0.64 with increasing wavelength. The decreasing behavior of refractive index is attributed due to the increase in transmission and decrease in absorption coefficient with increasing wavelength. The film exhibits reasonably high transmittance (>80%) in the visible region. Absorbance coefficient α and film thickness (d) were calculated from the interference of fringes of transmittance spectrum. The band gap and thickness of the film were found 3.02 eV and 275nm, respectively. The thickness of the film measured by envelope method is validated with cross-section micrograph of SEM images which is about 285 nm. The real part of the dielectric function of nanostructured ZnO decreases with increasing wavelength where as the imaginary part of dielectric constant increases with increasing wavelength. The observed high value of refractive index n and real part of dielectric constant ϵ at lower wavelength is due to band edge absorption of carriers. The dispersion relation shows the increase of complex refractive index and dielectric constant at the high frequency regime is due to the discharging of defect levels using optical excitation of carriers in the visible region.
Particle size and convergent electron diffraction patterns of triangular prismatic gold nanoparticles
Authors: Fernando-Marquez Clemente , Mondragón-Galicia Gilberto , Bazán-Díaz Lourdes , Reyes-Gasga José
Published: August 2021

Convergent beam diffraction (CBED) patterns of nanoparticles are possible. CBED of triangular prismatic shaped Au nanoparticle with focus on diffraction pattern symmetry and forbidden reflections observed along [111] and [112] zone axes are reported in this work. It is well known that the CBED patterns of nanoparticles of 30 nm or less in size only show bright kinematical discs. The dynamic contrast with Kikuchi and sharp HOLZ lines within the bright discs, as observed in CBED of volumetric materials, is well observed in particles larger of 500 nm in size. In addition, it is shown that the 1/3[422] and 1/2[311] weak forbidden reflections observed in the [111] and [112] electron diffraction patterns of these particles do not modify the symmetry of the CBED patterns, but they disappear as the size of the particle increases. The symmetry of the CBED patterns are always observed in concordance with the space group Fm3m (No. 225) of the Au unit cell. The possible explanations for observing forbidden reflections are the incomplete ABC stacking due to surface termination and the stacking faults in the fcc structure.
Susceptible-Infected-Recovered model study using free particle dynamics
Authors: Garzón Fernando , Orozco Olvera , Castro Jorge , Figueroa Aldo
Published: August 2021

A study on the epidemiologic Susceptible-Infected-Recovered (SIR) model is presented using free particle dynamics. The study is performed using a computational model consisting of randomly allocated particles in a closed domain which are free to move inrandom directions with the ability to collide into each other. The transmission rules for the particle–particle interactions are based on the main viral infection mechanisms, resulting in real–time results of the number of susceptible, infected, and recovered particles within a population of N= 200 particles. The results are qualitatively compared with a differential equation SIR model in terms of the transmission rate β, recovery rate γ, and the basic reproductive number R0, yielding overall good results. The effect of the particle density ρ on R0 is also studied to analyze how an infectious disease spreads over different types of populations. The versatility of the proposed free–particle–dynamics SIR model allows to simulate different scenarios, such as social distancing, commonly referredto as quarantine, no social distancing measures, and a mixture of the former and the latter. It is found that by implementing early relaxation of social distancing measures before the number of infected particles reaches zero, could lead to subsequent outbreaks such as the particular events observed in different countries due to the ongoing COVID–19 health crisis
Descemetocele associada à distiquíase bilateral em cão: Relato de caso
Authors: Rodrigues Ivanilce
Published: August 2021

This study aims to report a case of bilateral descemetocele associated with dystichiasis, which received surgical treatment. Bilateral keratoplasty with pedicled conjunctival flap and manual epilation. The patient (Shih Tzu dog, 5 years old) was seen at the Doctor Vet clinic (Nucleus of Veterinary Specialties), located in the Commercial Area Local Residencial Norte, Quadra 712, Bloco G, Loja 15 Asa Norte - Brasília DF. The tutor reported that the patient was quieter than usual, with a lot of eye discharge, keeping her eyes always closed and showing a lot of pain when cleaning. In the specific physical examination, the patient was responsive to the threat, when evaluating the eyeball, bilateral dystachiasis (eyelids), presence of greenish secretion in the mucosa of both eyes, hyperemic conjunctiva of both the right and left eyes was observed in the cornea was noted, with the aid of a slit lamp, the right eye with intense and diffuse edema with vessels and descemetocele, already in the left eye, in addition to the same corneal changes of the right eye, showed dorsal bullous keratitis. The fluorescein test was performed for diagnostic purposes. In view of the above, the animal was diagnosed with bilateral descemetocele and dystichiasis. For treatment, keratoplasty and manual epilation were indicated respectively. Keratoplasty using a pedicled conjunctival graft proved to be effective, repairing and preventing the progression of the descemetocele and consequently corneal rupture in both eyes, leaving only a scar on the cornea. However, since it is a patient who presents with cilia disorders, periodic clinical monitoring is essential.
Avaliação comparativa entre dois glicosímetros portáteis e o método laboratorial enzimático colorimétrico na dosagem glicêmica em cavalos
Authors: TAVARES KARIN HELOISE TAVARES
Published: August 2021

In the equine clinic, the reference system for measuring blood glucose is the colorimetric enzymatic laboratory method. However, equipment, specific reagent and more time are required to perform it. Due to practicality, portable glucometers have been gaining ground in veterinary medicine, providing the result quickly, facilitating the measurement of blood glucose in the field. Several studies have used portable glucometers to measure blood glucose in horses, however, there are still many controversies about the reliability of their results compared to the enzymatic method. Therefore, the objective of this work was to evaluate the use of two portable glucometers for the measurement of blood glucose in horses considering the conventional laboratory test as control. For this purpose, the Wellion GLUCO CALEA® portable veterinary glucometer and the ACCU-CHEK Performa® human portable glucometer were evaluated and compared with the colorimetric enzymatic test. It was concluded that the ACCU-CHEK Performa® glucometer can be used for rapid blood glucose tests in horses.
Contenção química e física de répteis: Revisão
Authors: Valandro Marilia
Published: August 2021

The Reptilia class (reptiles) is composed of 8000 species split into four orders: Chelonia (turtles), Crocodilia (crocodilians), Rhynchocephalia (tuatara) and Squamata (lizards and snakes). They are ectothermic animals with sluggish metabolism, lack functional diaphragm, performing the breathing with help of other mechanisms; the response to drugs is differently. There are practically no docile species within this group of animals, requiring physical restraint or chemical restraint. There are different methods to perform the management of physical restraint of each species, each species with a different characteristic to using anesthetics for chemical restraint. In all procedures where the animals are anesthetized have a pre-anesthesia care performed with the use of anesthetic drugs before anesthesia, observation during maintenance of anesthesia, besides monitoring with evaluation of physiological parameters and different reflexes that those animals exhibit during anesthesia.
Dermatopatia secundária ao hiperestrogenismo em cão macho: Relato de caso
Authors: Barbosa Rafaela
Published: August 2021

Hyperestrogenism in dogs has several etiologies, among them, the result of the excessive production of estrogen by testicular or ovarian tumors. It is also described that it may have its origin due to an imbalance between the androgen and estrogen hormones. As a result of hyperestrogenism, clinical dermatoses are manifested, such as symmetrical bilateral alopecia, thinner coat, easily detachable, variable hyperpigmentation. The diagnosis is based on history, anamnesis, clinical signs, testicular ultrasound, hormonal measurement of serum estrogens and histopathological examination. The treatment of choice is orchiectomy. The aim of the present study is to report the occurrence of a dermatosis secondary to hyperestrogenism in a young dog.
Combinação da cetamina e da xilazina para reduzir a dor durante a eletroejaculação em cães
Authors: Oliveira Rodrigo
Published: August 2021

The present study evaluated the efficiency of a ketamine-xylazine combination to attenuate the pain associated to electroejaculation (EEJ) in dogs. To that end, 10 dogs of undetermined breed were anesthetized (i.m.) with a mixture of 8mg.kg-1 ketamine hydrochloride (Cetamin®, Syntec, Brazil) and 1mg.kg-1 IM xylazine hydrochloride (Xilazin®, Syntec, Brazil) and subjected to EEJ procedures. Painful stimuli were detected by cardiorespiratory rate, measured every 5 min, and body temperature, taken before and after EEJ. Mean values for the parameters evaluated decreased, suggesting that the anesthesia protocol used is safe for semen collection by EEJ and can relieve the pain associated to this procedure.Semen, collection, mammals
Perspectiva de tutores de cães e gatos de Manaus/AM sobre cardiopatias em pequenos animais
Authors: Mello Talita
Published: August 2021

Heart diseases in the small animal clinic are among the main casuistry in senile animals, this is mainly due to the new awareness present in the tutors' treatment of animal welfare, a factor that implies the recurrent increase in the longevity rates of companion animals. However, under the terms of Veterinary Preventive Medicine, there is a relapsed nature of the owners regarding the importance of routine consultations for the general health of dogs and cats, in this case, aimed at early diagnosis and treatment adapted to the promotion of a better quality of life for cardiopathic animals. In this context, the present study investigated the previous knowledge of the population of Manaus / AM about heart disease in small animals and its importance in the veterinary clinical routine for the application of Preventive Veterinary Medicine. Data obtained from a registration questionnaire answered by 102 pet tutors interested in scheduling care for animals in the social action “III Setembro Vermelho Animal”, which took place on September 29 and 30, 2020, were analyzed. The prerequisite for participation was the animal is over five years old and the tutor answers the entire questionnaire through an online form, applied between 22 and 28 September 2020, disseminated through publications on news portals and social networks of the coordination and organizing committee of the course event Graduation Course in Veterinary Medicine at CEUNI - FAMETRO, Manaus.
A importância da linguagem corporal na consulta veterinária com tutores idosos, desafios e limitações
Authors: Schwittay Nayara , . Anderson Scherer
Published: August 2021

This work intends to carry out the importance of body language in veterinary consultation with elderly tutors, it challanges and limitations. Throughout the work we will discuss this subject, based on a questionnaire with a veterinarian, addressing daily issues in a clinical routine with the elderly, their difficulties and possible methods of improvement for this condition. At the end of the article, these results will be discussed and suggestions for future research will be presented.
Alterações congênitas em filhotes da raça Pug decorrente de acasalamento consanguíneo: Relato de caso
Authors: Baldassaune de Holanda Letícia
Published: August 2021

Crossbreeding between individuals with a high degree of kinship often generate deformities to the fetuses. Inbreeding provides the formation of recessive genes that cause acrosomal defects responsible for malformations that can bring risks to the newborn's life. The objective was to report the follow-up and attendance to a delivery of a female PUG breed whose crossing took place with her grandfather, generating inbreeding and causing two neonates who had congenital malformations. The animal arrived at Tolevet – the veterinary clinic –, located in Toledo - Paraná, in labor, presenting uterine contractions and swelling in the region of the uterus in the abdomen. On physical examination, vital parameters were normal. At birth, seven puppies were born who received the care of removing the placental pouch, clearing the airways and umbilical ligation. Two puppies had congenital deformity; one had concurrent cleft lip with cleft palate (palatoschisis), the second, already in a state of death, presented abnormal fluid accumulation in fully edematous fetal tissue, defined as fetal hydrops. This report demonstrates the importance of avoiding common ancestors consanguineous mating, in order to minimize the incidence of birth defects in neonates that are incompatible with life or that pose a risk to the animal's health and quality of life.
Hipercalcemia em cadelas portadoras de neoplasia mamária malignas
Authors: Caliani Carrera Alefe , . Claudia Russo , . Sandra Maria Simonelli , . Marcela Baggio Luz , . Isabela Ferraro Moreno , . Ana Paula Frederico Rodrigues Loureiro Bracarense
Published: August 2021

Malignant hypercalcemia is a paraneoplastic syndrome. It has been detected in several types of malignant tumours in dogs, such as lymphomas, and also in mammary neoplasms, without the exact determination of the mechanisms involved in its occurrence as well as its incidence. In this study, 100 bitches with mammary malignant neoplasia, diagnosed by histopathological analysis, were submitted to clinical evaluation for disease staging, haematological evaluation, serum biochemistry, including renal function tests, hepatic and total calcium serum levels and ionized fraction. These parameters were analyzed at the time of the initial attendance and 30 days after the treatment. The most frequent histological pattern was carcinoma in mixed tumors (26%). In 52% of the diseased dogs, hypercalcemia was observed by means of ionized calcium dosing, which was not verified by means of total calcium dosing, where only 4% presented hypercalcemia. No correlation was found between hypercalcemia and the histological pattern of the neoplasms. However, the correlation was verified between hypercalcemia and more advanced stages of the disease, mainly from stage III, suggesting that the detection of hypercalcemia may be correlated with worse prognosis, showing the importance of the research concerning the presence of paraneoplastic syndromes in bitches with mammary neoplasms.
Análise comparativa entre glicosímetros portáteis e método laboratorial para a dosagem de glicemia em bovinos
Authors: De Morais Aline , Pozzatti Pricilla
Published: August 2021

Glucose is considered an important source of energy for cells, fetal growth and milk production in ruminants. Some diseases can be diagnosed by changes in blood glucose levels, which can currently be measured by two methods: the laboratory method and the method using portable glucometers. Therefore, the objective of this study was to carry out a comparative analysis of glucose, measured with a portable glucometer for human use and another for veterinary use, with the laboratory method, considered the gold standard, to assess whether portable equipment can be accurate in blood glucose measurement at field, in cattle. Blood was collected from 17 bovines through the coccygeal vein and the samples were placed in a tube with sodium fluoride for colorimetric enzymatic laboratory analysis, and for the measurement of glucose concentration in portable glucometers, 1 drop of blood was used. The data showed normal distribution by the Shapiro-Wilk test (P = 0.128) and in the comparative analysis provided by the Tukey test (P
Criptorquidismo em equinos: Revisão de literatura e relato de 20 casos
Authors: Melo Ubiratan , Ferreira Cíntia
Published: August 2021

This article aims to review the anatomical and pathophysiological aspects of cryptorchidism in the equine, as well as to report a series of 20 cases treated clinically or surgically. Cryptorchidism consists of a complex developmental change, limited to sex, being the most prevalent non-lethal developmental defect in the horse. This disorder occurs when there is a failure in the normal descent of one or both testicles, from their fetal position in the sub-lumbar area through the inguinal canal to the scrotum. Between the years 2013 and 2020, twenty horses, with an average age of 7.1 + 1.69 years, were examined for the diagnosis and treatment of cryptorchidism. All animals were examined on the property of origin and underwent a general clinical examination. General clinical examination (anamnesis and physical examination), transrectal palpation and ultrasonography (transrectal and trans abdominal) were performed on all animals to identify the retained gonad. With the exception of two cases, all animals were referred for surgery according to the criteria of the history of cryptorchidism reported by the owner and identification of the gonad retained at the time of the clinical examination. The cryptorchid testicle was removed by flank laparotomy. The chosen technique proved to be easily applicable at the field level, and no complications were observed in this series of cases.
Pengaruh Motivasi Belajar Terhadap Hasil Belajar Matematika Peserta Didik
Authors: Novianti Chatarina , Sadipun Berty , Balan John M
Published: August 2021

This study aims to determine (1) learning motivation towards mathematics learning outcomes for Ende 11 students in Ende Regency. (2) learning outcomes of students of SDI Ende 11, Ende Regency. (3) to prove whether there is an influence of learning motivation on mathematics learning outcomes of SDI Ende 11 students. The sampling technique was done purposively on a questionnaire that was made in order to obtain actual data. The instrument of this study was the questionnaire and documentation of students' mathematics learning outcomes in SDI Ende 11. Data analysis techniques used product moment analysis analysis. The results of the study showed that the hypothesis testing obtained Fcount = 14.598 and Ftable = 4.20, meaning that there was a significant influence between learning motivation towards mathematics learning outcomes of classes III, IV and V SDI Ende 11. So the regression equation can be used to predict or predict the magnitude of the criterion variable (Y) based on the predictor variable (X). The results of these analysts prove that the constant coefficient on the linear model is 0.001 significantly smaller than 0.05, meaning that the regression coefficient of mathematics learning outcomes is significant. Conclusion, the effect value is R Square = 0.343, this value implies that the influence of learning motivation on mathematics learning outcomes is 34.3% and 65.7% is determined by variables or other factors.

Keywords: Learning Motivation, Mathematics Learning Outcomes
Kandungan Mineral dan Struktur Kristal Batu Sekis
Authors: Setiawan Muhamad Ragil , Siregar Rahmat Nawi
Published: August 2021

This study aims to determine the mineral content and crystal structure of schist rocks in South Lampung. The method used in this research is the X-ray diffraction method to see the lattice parameters and the crystal structure of the schist rocks. Based on data processing, information was obtained that two main minerals were found, namely quartz and albite minerals. In conclusion, the Albit minerals found in the two samples of rock crystal schists in South Lampung have the same crystal structure and lattice parameters, while the quartz minerals from the two samples have different crystal structures and lattice parameters.

Keywords: Lampung, Schis, XRD, Crystal Structure
Hasil Belajar IPA Berdasarkan Gaya Belajar Siswa
Authors: Adawiyah Tri Ambarwati , Harso Aloisius , Nassar Adrianus
Published: August 2021

This study aims to determine the differences in science learning outcomes of class VIII students of SMP Negeri 1 Larantuka who have visual, auditory and kinesthetic learning styles for the 2019/2020 academic year. The samples in this study were class VIII I and VIII J SMP Negeri 1 Larantuka. The research method used is quantitative with data analysis techniques using One Way Anova. Student learning styles are measured using a questionnaire that has been tested for validity and reliability first. Meanwhile, the learning outcome variable used the documentation method. The results of the F test showed that the value of Fcount <Ftable is 0.198 <2.53 with a significance value of 0.821> 0.05. In conclusion, there is no significant difference in science learning outcomes between students who have visual, auditory and kinesthetic learning styles.

Keywords: Learning Style; Science Learning Outcomes
Resistivitas Batuan Berdasarkan Metode Geolistrik Konfigurasi Schlumberger untuk Menentukan Potensi Air Tanah Sebagai Acuan Sumur Bor
Authors: Fadilah Fadilah
Published: August 2021

The purpose of this study is to analyze rock resistivity based on the geoelectric method of the Schlumberger configuration to determine the potential for groundwater as a reference for boreholes. The method used in this research is the geoelectric resistivity method with a Schlumberger configuration. Data acquisition modeling was analyzed using Progress Version 3.0 to describe the subsurface based on measurement sounding points in the field. The main targets for these measurements are confined aquifer traps and sandstone stratigraphy. Field measurement points are at coordinates S 030 43 '52.2 "and E 1020 19' 27.1". The results of this study indicate that the layer that is thought to be the groundwater carrier layer is found at a depth of about 64.99 meters to 150.86 meters with a layer thickness of 85.87 meters, which is in the form of sandstone density with a resistivity value of 5.39 ohm meters. The iteration error scale value in this study is, 5.05% RMS. In conclusion, the results obtained can provide specific information for groundwater drilling actors in the research location.

Keywords: Groundwater, Geoelectricity, Resistivity, Schlumberger
Identifikasi Batuan Granit Daerah Prospek Panas Bumi Nyelanding menggunakan Metode Magnetik
Authors: Siregar Ahmat Munawir , Dewi Ira Kusuma , Ngatijo Ngatijo
Published: August 2021

This study aimed to identify granite rocks around the Nyelanding geothermal area, especially in the geothermal manifestations. This research used the magnetic method to analyze the subsurface structure of the geothermal area. Correction of magnetic data was performed in Microsoft excel 2010 software and two-dimensional modeling was performed using Oasis Montaj 8.4. The results showed that there are three layers of rock under Nyelanding hot springs, namely granite with a susceptibility of 0.009 - 0.05 SI to a depth of 500 meters and a layer of sandstone - clay, as well as layers of clay, gravel and silt with a susceptibility of 0.00001 - 0, 00005 SI. In conclusion, the local geology of the Nyelanding hot spring area is dominated by the presence of granite to a depth of 500 meters. The results of forward modeling on layers A-A' and C-C' show the subsurface structure of Nyelanding hot springs in the form of a granite rock basin which is estimated to be able to accumulate geothermal energy.

Key words: Nonvolcanic Geothermal, Magnetic Method, Granite Susceptibility, Forward Modeling
A new Mexican species of Messatoporus Cushman (Hymenoptera: Ichneumonidae: Cryptini)
Authors: Kasparyan D.R.
Published: August 2021

Messatoporus flavator sp. n. is described from the south of Mexico (Chiapas).
EFFECT OF TRANSGLUTAMINASE TREATMENTON TRANSITION OF SOLIDS FROM MILK TO CHEESE
Authors: Yashkin A. I. , Mazalevskij V. B.
Published: August 2021

Transglutaminase is an enzyme that forms cross-links between protein molecules and affects such protein properties as the ability to gel, thermal stability, water retention, etc. One of the important tasks of the food industry is to increase the yield of products, in particular soft cheeses, in the production of which a significant part of the whey with dissolved substances is separated from milk. Therefore, the aim of the work was to study the effect of transglutaminase on the transition of milk solids to cheese, depending on the stage of application of the enzyme. Transglutaminase in an amount of 0.05% by weight of milk (1.6 units in terms of 1 g of protein) was introduced in two versions: simultaneously with the milk-clotting enzyme and after cutting the clot. It was found that the use of transglutaminase does not affect the duration of acid-rennet coagulation of milk. The data obtained indicate that when transglutaminase is introduced into milk simultaneously with the milk-converting enzyme, the transition of milk solids to cheese increases by 5.15%, including fat by 3.07%, compared to samples without transglutaminase. When transglutaminase is added at the stage of processing the clot, a denser consistency of cheese is formed.
THE RESULTS OF THE USE OF BIOTECHNOLOGICAL DRUGS IN VETERINARY MEDICINE, PROMISING FOR MEDICINE (PART 1)
Authors: Alikin Yu. S. , Alekseeva M. V. , Ermolaev V. V. , Klimenko V. P. , Telegina Yu. V.
Published: August 2021

Cell and serum nucleases are considered as a natural biological barrier, one of the first links in the body’s antiviral defense: nucleases act on viruses that the usual immunological barrier cannot resist. Inactivation of the enzymatic properties of nucleases also leads to the loss of their antiviral activity. It was found that the nucleases do not inactivate the native virus outside the cell and act mainly on the virus that multiplies in the cells. There is a direct dependence of the antiviral activity of endonuclease on the concentration of the enzyme in the medium. The first antiviral drug created on the basis of the Serratia marcescens endonuclease was called bacterial endonuclease. Its technology was developed by joint research of NIKTI BAS of the Ministry of Medical Industry (Berdsk, Novosibirsk region) and ICIG SB of the USSR Academy of Sciences in 1973–1984. Serratia marcescens endonuclease is capable of cleaving the nucleic acids of both RNA and DNA-containing viruses. The enzyme inhibits the reproduction of vesicular stomatitis and smallpox vaccine viruses in chicken fibroblast cell culture, respectively. It was the first antiviral drug in the history of beekeeping, designed to prevent acute and chronic paralysis and other viral diseases of bees. The drug was also intended as an antiviral agent for a wide range of diseases in various organisms. The effectiveness of bacterial endonuclease as a means of prevention and treatment of respiratory viral diseases in calves was studied. The research was carried out at the industrial complex for growing heifers of the Gosnensky state farm in the Leningrad region on calves of a black-and-white breed of 20–60 days old. For the experiments, we used bacterial endonuclease produced by the Vyshnevolotsky Plant of Enzyme Preparations or NICTI BAS of the Ministry of Medical Industry. In the future, NIKTI BAV together with Diafarm LLC developed a second – generation antiviral drug, endoglucin, based on bacterial endonucleosis. Production experiments to study its effect as a therapeutic and prophylactic agent for respiratory diseases of calves were conducted during 2007– 2011. in the agricultural complex «Prichulymsky» of the Achinsky district of the Krasnoyarsk Territory with the participation of the Department of Epizootology and Parasitology of the Faculty of Veterinary Medicine of KrasGAU and in CJSC «Suzdalskoye» of the Dovolensky district of the Novosibirsk region. Prophylactic use of endoglucin in calves with bronchopneumonia can reduce the incidence from 2.2 to 3.1 times. The drug endoglucin in combination with drugs indicated for the treatment of pulmonary pathology, has therapeutic effectiveness in bronchopneumonia of calves.
QUALITY AND NUTRITIONAL VALUE OF FREEZED SEA BUCKTHORN POWDER
Authors: Burmistrova O. M. , Burmistrov E. A. , Naumova N. L.
Published: August 2021

The use of phytopowders as food additives allows you to create highly nutritious mixtureswith a pronounced taste and aroma of fresh fruits and berries. Fruit and berry powders are already usedin the production of jelly, fruit drinks, drinks, juices and sauces based on domestic plant raw materials witha high proportion of biologically active substances. The most important phytonutrients of sea buckthorn fruits(Hippophae rhamnoides L.) are carotenoids, flavonoids, anthocyanins, sugars, organic and amino acids, tannins and pectin substances, phospholipids, macro- and microelements. The aim of the research was to study thequality and nutritional value of freezedried sea buckthorn powder. Sublimated sea buckthorn was the objectof study (TU 10.39.25-007-0111115841-2018) manufactured by IP A.N. Mazurina (Russia, Kaluga region,Borovsky district, Borovsk). The quality of packaging and labeling, as well as organoleptic characteristics,nutritional value and mineral composition of raw materials have been studied. It was determined that themarking of sublimated sea buckthorn does not comply with the regulated requirements of GOST R 51074-2003and TR CU 022/2011. Organoleptic characteristics of phytopowder are identified as characteristic of thistype of raw material. The actual protein and fat content of the test material does not correspond to the levelsstated by the manufacturer. The studied raw materials are distinguished by a variety of chemical composition,namely, the content of protein, carotenoids, vitamins E and A, lipids, dietary fiber, unique trace elements – Al,Co, Cr, Cu, Fe, Li, Mn, Ni, Ti, Zn.
REGIONAL FEATURES OF THE FORMATION OF THE NOSOLOGICAL PROFILE OF INFECTIOUS ANIMAL DISEASES IN THE REPUBLIC OF BURYATIA
Authors: Badmaeva O. B.
Published: August 2021

On the territory of the Republic of Buryatia, the epizootological profile is formed by 8 nosological forms of infectious pathology of farm animals. The dominant epizootic significance is rabies, leptospirosis, brucellosis. Rabies was registered in 8 (38.1 %) rural administrative districts of the republic and in the urban district of Ulan-Ude. In the total number of cases of rabies, the disease of farm animals occupies 48.3%, domestic carnivores-3.9, and in 47.6% of cases, epizootic foci began among wild animals. The main reservoir of the rabies virus is the wild fox: 46.2 % in the total number of cases and 97.1 % - in autochthonous epizootic foci. Leptospirosis in the conditions of Buryatia is an indigenous natural focal infection with a pronounced indicator of epizootic manifestation in the form of infection of animals without clinical signs. It is registered in 11 (52.4 %) rural administrative districts of the republic in 1.5 % of cattle and 0.6% of horses. The unfavorable situation with bovine brucellosis persisted from 2009 to 2018, 26 unfavorable points were registered. In the Jida district, 5 km from the state border with Mongolia, brucellosis was first registered in a dog. In this area, the corridor of migration of wild animals across the border passes, which confirms the assumption of the existence of natural foci of brucellosis in the transboundary territories of Russia and Mongolia and the introduction of the pathogen from the natural focus to the territory of the buffer zone farms.
AVAILABILITY OF BIBLIOGRAPHIC MANUALS ON NATURAL SCIENCES IN THE PROCESS OF STUDYING NORTH ASIA IN THE XVIII-EARLY XX CENTURIES
Authors: Ehrlich V. A.
Published: August 2021

The article considers the bibliographic equipment of scientific research of the pre-revolutionary period in the field of natural sciences in Siberia and the Far East.
Compression on the Twisted Jacobi Intersection
Authors: Dryło Robert
Published: August 2021

Formulas for doubling, differential addition and point recovery after compression were given for many standard models of elliptic curves, and allow for scalar multiplication after compression using the Montgomery ladder algorithm and point recovery on a curve after this multiplication. In this paper we give such formulas for the twisted Jacobi intersection au2 + v2 = 1, bu2 + w2 = 1. To our knowledge such formulas were not given for this model or for the Jacobi intersection. In projective coordinates these formulas have cost 2 M +2 S +6 D for doubling and 5 M + 2 S + 6 D for differential addition, where M; S; D are multiplication, squaring and multiplication by constants in a field, respectively, choosing suitable curve parameters cost of D may be small.
NLRP3 Inflammasome: A Starring Role in Amyloid-β- and Tau-Driven Pathological Events in Alzheimer’s Disease
Authors: Van Zeller Mariana , Dias Diogo , Sebastião Ana M. , Valente Cláudia A.
Published: August 2021

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease commonly diagnosed among the elderly population. AD is characterized by the loss of synaptic connections, neuronal death, and progressive cognitive impairment, attributed to the extracellular accumulation of senile plaques, composed by insoluble aggregates of amyloid-β (Aβ) peptides, and to the intraneuronal formation of neurofibrillary tangles shaped by hyperphosphorylated filaments of the microtubule-associated protein tau. However, evidence showed that chronic inflammatory responses, with long-lasting exacerbated release of proinflammatory cytokines by reactive glial cells, contribute to the pathophysiology of the disease. NLRP3 inflammasome (NLRP3), a cytosolic multiprotein complex sensor of a wide range of stimuli, was implicated in multiple neurological diseases, including AD. Herein, we review the most recent findings regarding the involvement of NLRP3 in the pathogenesis of AD. We address the mechanisms of NLRP3 priming and activation in glial cells by Aβ species and the potential role of neurofibrillary tangles and extracellular vesicles in disease progression. Neuronal death by NLRP3-mediated pyroptosis, driven by the interneuronal tau propagation, is also discussed. We present considerable evidence to claim that NLRP3 inhibition, is undoubtfully a potential therapeutic strategy for AD.
Intrahepatic Cholestasis Is a Clinically Significant Feature Associated with Natural History of X-Linked Myotubular Myopathy (XLMTM): A Case Series and Biopsy Report
Authors: Molera Cristina , Sarishvili Tinatin , Nascimento Andrés , Rtskhiladze Irakli , Muñoz Bartolo Gema , Fernández Cebrián Santiago , Valverde Fernández Justo , Muñoz Cabello Beatriz , Graham Robert J. , Miller Weston , Sepulveda Bryan , Kamath Binita M. , Meng Hui , Lawlor Michael W.
Published: August 2021

X-linked myotubular myopathy (XLMTM) is a rare, life-threatening congenital myopathy characterized by profound skeletal muscle weakness, respiratory distress, and motor dysfunction. However, pathology is not limited to muscle and can be associated with life-threatening hepatic peliosis. Hepatobiliary disease has been reported in up to 17% of XLMTM patients but has not been extensively characterized. We report on five XLMTM patients who experienced intrahepatic cholestasis in their disease natural history, illustrating the need to further investigate these manifestations. These patients shared presentations that included pruritus, hypertransaminemia, and hyperbilirubinemia with normal gamma-glutamyl transferase, following infection or vaccination. Three patients who had genetic testing showed no evidence of genetic mutations associated with familial cholestasis. In one patient, progression to cirrhotic, decompensated liver disease occurred. Further investigations into the molecular pathomechanism underpinning these clinical observations in XLMTM patients will be important for informing patient care.
Measuring General Expectations of Advanced Stage Treatment Outcomes in Parkinson’s Disease
Authors: Loftus Andrea M. , Nielsen Chloe , Corti Emily J. , Starkstein Sergio , Gasson Natalie , Egan Sarah J.
Published: August 2021

Background: Recent research suggests that a significant number of those who receive advanced treatments for Parkinson’s disease (PD) do not report improvements for some symptoms, which may relate to their pre-treatment expectations. It is important that expectations of treatment are measured and discussed prior to advanced treatment. Objective: The primary aim of this study was to develop a measure of treatment expectations of two advanced-stage treatments in PD, deep brain stimulation (DBS), and Levodopa/Carbidopa Intestinal Gel (LCIG). A secondary aim was to explore potential predictors of treatment expectations. Methods: The questionnaire-based measure was developed by researchers in conjunction with a highly experienced clinician, and evaluated treatment expectations in 189 people aged 46–91 years (M = 71.35, SD = 8.73; 61% male) with idiopathic PD. Results: The overall measure demonstrated excellent internal consistency (α= 0.96). Exploratory factor analysis suggested the scale was unidimensional for both DBS and LCIG. Participant expectations of the two treatments differed significantly, with expectations being higher for DBS. Perceived symptom severity was the strongest predictor of treatment expectations. Conclusion: This scale has potential to inform clinicians about client expectations prior to advanced stage therapy for PD, with a view to the management of these expectations. Further evaluation of the scale is required across different treatment contexts.
Effectiveness of Long-Term Physiotherapy in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Authors: Okada Yohei , Ohtsuka Hiroyuki , Kamata Noriyuki , Yamamoto Satoshi , Sawada Makoto , Nakamura Junji , Okamoto Masayuki , Narita Masaru , Nikaido Yasutaka , Urakami Hideyuki , Kawasaki Tsubasa , Morioka Shu , Shomoto Koji , Hattori Nobutaka
Published: August 2021

Background: Long-term physiotherapy is acknowledged to be crucial to manage motor symptoms for Parkinson’s disease (PD) patients, but its effectiveness is not well understood. Objective: This systematic review and meta-analysis aimed to assess the evidence regarding the effectiveness of long-term physiotherapy to improve motor symptoms and reduce antiparkinsonian medication dose in PD patients. Methods: Pubmed, Cochrane, PEDro, and CINAHL were searched for randomized controlled trials before August 31, 2020 that investigated the effectiveness of physiotherapy for 6 months or longer on motor symptoms and levodopa-equivalent dose (LED) in PD patients with Hoehn and Yahr stage 1– 3. We performed random effects meta-analyses for long-term physiotherapy versus no/control intervention and estimated standard mean differences with 95% confidence intervals (CIs). Levels of evidence were rated by the Grading of Recommendation Assessment, Development and Evaluation approach. Results: From 2,940 studies, 10 studies involving 663 PD patients were assessed. Long-term physiotherapy had favorable effects on motor symptoms in off medication state [– 0.65, 95% CI – 1.04 to – 0.26, p = 0.001] and LED [– 0.49, 95% CI – 0.89 to – 0.09, p = 0.02]. Subgroup analyses demonstrated favorable effects on motor symptoms in off medication state by aerobic exercise [– 0.42, 95% CI – 0.64 to – 0.20, p < 0.001] and LED by multidisciplinary rehabilitation of primarily physiotherapy [– 1.00, 95% CI – 1.44 to – 0.56, p < 0.001]. Quality of evidence for aerobic exercise and multidisciplinary rehabilitation were low and very low. Conclusion: This review provided evidence that long-term physiotherapy has beneficial impact on motor symptoms and antiparkinsonian medication dose in PD patients and could motivate implementation of long-term physiotherapy.