bluuebunny/crossref_metadata_2025 huggingface dataset:
The texture changing of fresh champignons under the influence of processing by accelerated electrons during the refrigeration storage
Authors: Fedynina N. I. , Karastoyanova O. V. , Korovkina N. V. , Shishkina N. S.
Published: November 2020

Technologies for processing and storage of food products using physical methods of exposure, in particular ionizing and non-ionizing radiation, have been actively developing in recent years. One of the types of ionizing radiation is processing by accelerated electrons, used to reduce losses, prolong the shelf life and sale of plant materials. The work has investigated champignons of the Agaricus bisporus species - the most common among cultivated mushrooms, which are a source of protein, containing useful micro- and macroelements, biologically active substances, vitamins of group B, PP, D. The dynamics of changes in texture as a qualitative indicator of the storage capacity of packaged fresh champignons in the process of refrigerated storage (at a temperature of +4...5 °C and a relative humidity of 85-90 %) for 29 days after treatment with accelerated electrons with an energy of 5 MeV in the range of accumulated doses from 0.8 to 3.2 kGy with a discreteness of 0.4 kGy. Treatment in the dose range of 3.4 kGy leads to a negative effect of changing storage capacity and is impractical. Treatment with accelerated electrons in the dose range from 0 to 3.2 kGy leads to an increase in storage capacity and reaches its extremum at 2 kGy. When extrapolating the results of experimental data, such a tendency is observed presumably up to a dose of 3.4 kGy. On the basis of experimental data, the dynamics of texture during storage after processing with accelerated electrons have been obtained, a mathematical model of the dependence of the limiting storage capacity in terms of the texture of mushrooms on the radiation dose has been constructed, and the modes of processing champignons have been established.
case of porencephaly complicated by central diabetes insipidus in a dog
Authors: HAYDARDEDEOĞLU ALI EVREN , ÇOLAKOĞLU EKREM ÇAĞATAY , ALIHOSSEINI HADI
Published: November 2020

Porencephaly is an extremely rare congenital disorder of the central nervous system characterized by focal cerebral cysts and cavities. Central diabetes insipidus is also a well-described condition in veterinary medicine. A 4-year-old Terrier dog was referred to the hospital with polyuria and polydipsia. Based on a diagnostic examination, porencephaly complicated by central diabetes insipidus was determined. Treatment consisted in administering intranasal desmopressin to the conjunctiva. The dog remains clinically healthy for 2 years. This case report reflects the MRI features of porencephaly and central diabetes insipidus associated with congenital porencephaly.
Structural Study of Wheat Gliadin in Different Solvents by Spectroscopic Techniques
Authors: Ribeiro Andresa , Leite Daiani , Scheibel Jóice , Soares Rosane , Silveira Nádya
Published: November 2020

Physicochemical properties of gliadin in different solvents (dimethyl sulfoxide (DMSO), H2O, and aqueous ethanol) and pH (9.8, 6.8, and 1.2) were investigated using dynamic light scattering (DLS), zeta potential (ZP), and attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR). Gliadin-DMSO and gliadin-deionized water (H2O) (pH 9.8) showed a lower size distribution, whereas samples solubilized in 60% aqueous ethanol presented a lower size distribution only at pH 1.2. ZP analysis showed that gliadin-H2O (pH 9.8) was the most stable evaluated system. ZP results of gliadin-DMSO indicated an unstable system, with the coexistence of several protein conformations. ATR-FTIR analysis showed that, in H2O, most protein conformations were β-sheets, while in DMSO a band at 1660 cm−1 appeared to be related to protein unfolding. The techniques proved to be effective in monitoring conformation and stability of all gliadin/solvent systems. Such information can be used in the development of new gliadin-based materials.
BRICS and a new model of hegemonic stability
Authors:   St. Petersburg State University, Tkachenko Stanislav , Coyle William ,   Babson College
Published: November 2020

BRICS as a forum of the largest developing economies is at the center of the global contem- porary political process. There are ongoing debates for more than a decade on the reasons for the establishment and the ways of assessing the efficiency of BRICS. Two major theoretical perspectives in the international political economy (IPE), namely economic nationalism and liberalism, have opposing views on many aspects of these debates. They emphasize the search for common interests, which places the five BRICS states into a single forum, and find a lack of shared values/interests, which inevitably leads to a collapse of the forum in the near future. This article puts forward the following hypothesis: the original willingness of BRICS members to transform the architecture of international finances to the profit of developing nations has been replaced recently by a desire to preserve some of the attractive features of todays’ global economy (low trade barriers, monetary stability, and free movement of investment) in the context of the decline of US hegemony. Today, BRICS member states share China’s intention to ensure the liberal nature of the international trading system while strengthening state control of public life according to the “embedded liberalism” model. To substantiate the hypothesis, the authors apply ideas from the neo-Marxist school of IPE, which is currently experiencing its renaissance.
Main achievements and further tasks for Korean-Russian economic cooperation: From trade to investment and innovation
Authors:   Kookmin University, Seoul, Lee Sang Joon
Published: November 2020

The article aims to examine the performance of trade and investment since the diplomatic normalization of relations between the Russian Federation (RF) and the Republic of Korea (ROK) and also suggests further areas for the development of economic cooperation between the two countries. The volume of trade between the two countries in 2019 has grown 116-fold compared to 1992. To increase trade volume, it is necessary to increase intra-industry trade to improve the mutual relationship. The direct investment of Korea into Russia has been increased, as well as diversified in different sectors. Korea’s total investment in Russia is approximately 2.75 billion USD, which is relatively small compared to investments made by Korea globally. Korea’s New Northern Policy seeks to strengthen cooperation with Russia. Korean companies must reevaluate the strategic importance of Russia. The lesson learnt from the previous experience of overcoming past crises is, first, to believe in the potential and capabilities of the Russian economy and market. The development of the Far East and the Arctic has made Russia’s energy supply chain more stable and flexible in responding to changes in the energy market. In addition, Russia is also becoming the center of the 4th Industrial Revolution thanks to its advanced scientific and technological capabilities, as well as the revival of its manufacturing industry. To advance economic cooperation between Russia and Korea, Korea has to invest in Russia’s global energy supply chain and participate in the formation of a global value chain in a certain industry by combining Russian advanced science and technology with Korean product development planning and global marketing capabilities. Specifically, The Far East, Arctic Development, and Triangle (or Quadrangle) Cooperation among ROK-DPRK-Russia (-China) will provide significant opportunities to Korean companies.
The “New Northern Policy” strategy and its constraints
Authors:   Hanyang University, Eom Gu Ho
Published: November 2020

The article evaluates the “New Northern Policy” of Moon Jae-in’s administration. Based on the evaluations, geopolitical risk management strategies of the Northern Policy, essential and feasible tasks and projects, and a guideline to establish cooperative governance are proposed. The characteristics of the New Northern Policy under Moon Jae-in’s leadership are as follows: 1) the idea of connecting the Republic of Korea with the continent through North Korea is more important task of the New Northern Policy than that of participation in the Eurasian integration process; 2) at the moment, the New Northern Policy cannot overcome geopolitical restrictions and it can be compared to a car equipped with a powerful noisy engine, which however cannot be moved; 3) due to many difficulties, it seems that the current administration may have fewer motivating factors to implement the New Northern Policy than to promote the New Southern Policy. To succeed in the New Northern Policy, the following tasks must be completed: finding a reasonable answer to Western sanctions against Russia and North Korea; actively promoting mini-lateral cooperation; establishing the Northeast Asian Development Bank with the participation of the United States, Japan, Russia and China; connecting the regulation of the North Korean nuclear issue to the creation of the “Northeast Railway Community”; strengthen the platform for successful implementation of the New Northern Policy.
Conceptualization of post-Soviet regime changes: Some intermediate results
Authors:   RAS Institute of Philosophy, Letnyakov Denis
Published: November 2020

The aim of the article is to analyze the attempts to conceptualize post-Soviet regime changes that have been undertaken over the past thirty years. For convenience, all concepts are grouped around three main approaches. The first one examines regime transformations in the former USSR from the point of view of a possible transition to democracy (transition paradigm); the second approach emphasizes the continuity between the post-Soviet political regimes and previous ones, overlooking fundamental differences between them; the third approach assumes that the post-Soviet transition did take place, however, it was “autocracyto-autocracy transition” (from one-party communist dictatorship to hybrid regimes or consolidated personalistic autocracies). The author considers regime change as transformation of some basic formal and informal rules of the game that determine the functioning of a given political system (from the way of making key decisions and allocating resources to the main channels for recruiting to the elite). As a result, the author proves that the third approach is the most relevant for understanding post-Soviet politics. Inter alia, its advantage is that it allows us to fit post-Soviet studies into the wider field of comparative political science: the analysis of post-Soviet politics, on the one hand, can significantly enrich our ideas about “how dictatorships work” at large, on the other hand, empirical knowledge about autocracies outside post-Soviet Eurasia and theories built on this basis will help us to understand the nature of authoritarianism in Russia’s “near abroad”.
Effective removal of fly ash by Penicillium chrysogenum and determination of direct fly ash toxicity with Daphnia magna
Authors: Ertit Taştan Burcu
Published: November 2020

This study demonstrates the removal of fly ash with Penicillium chrysogenum, a newly isolated species of fungus, and acute toxicity assessment with Daphnia magna. In the study, two different removal mechanisms were compared, both bio-removal and bio-sorption. Six different ash and three different biomass concentrations were used simultaneously. Although other fungal species in the literature failed at such a high concentration of fly ash, P. chrysogenum was able to tolerate it even at 10% concentration. The highest bio-removal yield was recorded as 100% at 0.5% fly ash concentration. Maximum bio-sorption yield was 95.27% after 24th hour. The evaluation results of fly ash bio-toxicity by D. magna showed that the no observed effect level (NOEL) was 0.2 mg/L and the low observed effect level (LOEL) was 0.5 mg/L. The element analysis, determined by ED-XRF, clarified that Ca, Si, Fe and S were the common elements in this ash. This is the first study in the literature where fly ash removal was carried out using P. chrysogenum for both bio-removal and bio-sorption and needs to be developed in the future.
Sewage surveillance for the presence of SARS-CoV-2 genome as a useful wastewater based epidemiology (WBE) tracking tool in India
Authors: Arora Sudipti , Nag Aditi , Sethi Jasmine , Rajvanshi Jayana , Saxena Sonika , Shrivastava Sandeep K. , Gupta A. B.
Published: November 2020

The infection with SARS-CoV-2 is reported to be accompanied by the shedding of the virus in fecal samples of infected patients. Earlier reports have suggested that COVID-19 agents can be present in the sewage samples and thus it can be a good indication of the pandemic extent in a community. However, no such studies have been reported in the Indian context. Hence, it becomes absolutely necessary to detect the presence of the SARS-CoV-2 in the wastewater samples from wastewater treatment plants (WWTPs) serving different localities of Jaipur city. Samples from different WWTPs and hospital wastewater samples were collected and wastewater based epidemiology (WBE) studies were carried out using the RT-PCR to confirm the presence of different COVID-19 target genes namely S gene, E gene, ORF1ab gene, RdRp gene and N gene. The results revealed that the untreated wastewater samples showed the presence of SARS-CoV-2 viral genome, which was correlated with the increased number of COVID-19 positive patients from the concerned areas, as reported in the publically available health data. This is the first study that investigated the presence of SARS-CoV-2 viral genome in wastewater, at higher ambient temperature (45 °C), further validating WBE as potential tool in predicting and mitigating outbreaks.
İşletme Stratejileri Perspektifinden Stratejik Yönetim Okulları
Authors: Yolsal Murat
Published: November 2020

Bu çalışmada Henry Mintzberg’in on stratejik yönetim okulu, birbirinin zıddı olan iki temel işletme stratejisi açısından ele alınmıştır. Çalışmanın kapsamı üç yönden sınırlandırılmıştır. Bunlardan ilki stratejik yönetim okullarının ele alınması hususudur. Stratejik yönetim yaklaşımları konusunda, farklı araştırmacılar farklı taksonomiler geliştirmişlerdir. Fakat bu taksonomileri derinlik arz eden bir bütünlüğe kavuşturanın Henry Mintzberg olduğu, akademik çevrelerce geniş bir kabul görmektedir. Bu sebepten ötürü çalışma Mintzberg’in yönetim okullarıyla sınırlandırılmıştır. İkincisi işletme stratejileri hususundadır. Bu noktada çalışma günümüzün temel iki yaklaşım olan pazar yaklaşımı ile kaynak tabanlı görüşü karşı karşıya getirmeyi amaçlamış ve yönetim okullarını bu bağlamda değerlendirmiştir. İlerleyen sayfalarda okuyucu, bazı yönetim okullarının pazar yaklaşımına, bazılarının kaynak tabanlı yaklaşıma yakın olduğuna, bazı okulların ise her iki yaklaşımı bütünleştirdiğine şahit olacaktır. Üçüncüsü kısıt ise çalışmanın stratejik yönetim düşüncesi tarihine yön veren makro düzeydeki olay ve olguları çalışmanın kapsamı dışında bırakmasıdır. Bu bağlamda, ilgi duyan okurlar, mikro düzeyde zuhur eden yönetim okullarının makro düzeydeki arka planını anlatan muhtelif kitaplardan faydalanabilirler.
mTOR Targeted Cancer Chemoprevention by Flavonoids
Authors: Badar ul Islam  , Khan Mohd Shahnawaz , Husain Fohad Mabood , Rehman Md Tabish , Zughaibi Torki A. , Abuzenadah Adel M. , Urooj Maryam , Kamal Mohammad Amjad , Tabrez Shams
Published: November 2020

Over the past several decades, plant-derived products (phytochemicals) have
been suggested to possess immense therapeutic potential. Among these phytochemicals,
different flavonoids have been reported for their potent anticancer activity. To exhibit
their anticancer potential, these flavonoids modulate different signaling pathways.
Among these pathways, the mammalian target of rapamycin (mTOR) and associated
phosphatidyl-inositol 3-kinase (PI3K)/protein kinase B (Akt) signaling cascade have
been reported as a pivotal modulator of cell survival, proliferation, and death/apoptosis.
Hence, targeting this cascade could be an ideal strategy to alleviate apoptosis and inhibit
proliferation in different forms of cancer. The targeting of PI3K/Akt/mTOR by
flavonoids have been well documented in the scientific literature. In the current study,
we have studied the anticancer potential of various flavonoids, especially flavones,
flavonols, and isoflavones that include apigenin, luteolin, baicalein, tangeretin, epigallocatechin-
3-gallate, genistein, and daidzein especially dealing with mTOR targeting.
Novel Antidiabetic Agents: Cardiovascular and Safety Outcomes
Authors: Siasos Gerasimos , Bletsa Evanthia , Stampouloglou Panagiota K. , Paschou Stavroula A. , Oikonomou Evangelos , Tsigkou Vasiliki , Antonopoulos Alexios S. , Vavuranakis Manolis , Tousoulis Dimitrios
Published: November 2020

Background:

Concerns of elevated cardiovascular risk with some anti-diabetic medications warranted
trials on the cardiovascular outcome to demonstrate cardiovascular safety of newly marketed anti-diabetic
drugs. Although these trials were initially designed to evaluate safety, some of these demonstrated significant
cardiovascular benefits.

Purpose of Review:

We reviewed the cardiovascular and safety outcomes of novel antidiabetic agents in patients
with type 2 diabetes and established cardiovascular disease or at high risk of it. We included the outcomes
of safety trials, randomized controlled trials, meta-analysis, large cohort studies, and real-world data, which
highlighted the cardiovascular profile of DPP-4is, GLP-1RAs and SGLT-2is.

Although DPP-4is demonstrated non-inferiority to placebo, gaining cardiovascular safety, as well
market authorization, SGLT-2is and most of the GLP-1RAs have shown impressive cardiovascular benefits in
patients with T2D and established CVD or at high risk of it. These favorable effects of novel antidiabetic agents
on cardiovascular parameters provide novel therapeutic approaches in medical management, risk stratification
and prevention.
Plant Polyphenols: Natural and Potent UV-Protective Agents for the Prevention and Treatment of Skin Disorders
Authors: Farjadmand Fatemeh , Karimpour-Razkenari Elahe , Nabavi Seyed Mohammad , Ardekani Mohammad Reza Shams , Saeedi Mina
Published: November 2020

:

Nowadays, destructive and immunosuppressive effects from long-term exposure to UV
radiation have been fully investigated and documented in the literature. UV radiation is known as the
main cause of skin aging and carcinogenesis. Hence, skin protection against anti-oxidative and immunosuppressive
processes is highly in demand. Now, plant polyphenols have been found as a versatile
and natural tool for the prevention and treatment of various skin diseases. The presence of a large
number of hydroxyl groups in the cyclic structure of polyphenols has induced valuable biological activities.
Among them, their UV protective activity has attracted lots of attention due to promising efficacy
and simple instruction to use.
Current Challenges and Limitations in the Studies of Intrinsically Disordered Proteins in Neurodegenerative Diseases by Computer Simulations
Authors: Akbayrak Ibrahim Y. , Caglayan Sule I. , Ozcan Zilan , Uversky Vladimir N. , Coskuner-Weber Orkid
Published: November 2020

Experiments face challenges in the analysis of intrinsically disordered proteins in solution due
to fast conformational changes and enhanced aggregation propensity. Computational studies complement
experiments, being widely used in the analyses of intrinsically disordered proteins, especially those
positioned at the centers of neurodegenerative diseases. However, recent investigations – including our
own – revealed that computer simulations face significant challenges and limitations themselves. In this
review, we introduced and discussed some of the scientific challenges and limitations of computational
studies conducted on intrinsically disordered proteins. We also outlined the importance of future developments
in the areas of computational chemistry and computational physics that would be needed for
generating more accurate data for intrinsically disordered proteins from computer simulations. Additional
theoretical strategies that can be developed are discussed herein.
Recent Advances in the Synthesis of Pyrazole Derivatives
Authors: Abdulla Afsina Cheriya Mukkolakkal , Aneeja Thaipparambil , Neetha Mohan , Anilkumar Gopinathan
Published: November 2020

Pyrazole and its derivatives have gained wide attention in pharmaceutical, agrochemical and biological fields as well as in industry. They exhibit various biological activities such as anti-pyretic, anti-microbial, anti- inflammatory, anti-tumor, anti-viral, anti-histaminic, anti-convulsant, fungicidal, insecticidal, etc. In this review, we summarise the recent advances in the synthesis of pyrazole derivatives using various methodologies and covers literature from 2017-2020.
Exploring Photoactivated Disinfection-Induced Bystander Effects on Microbial Biofilms of Aggregatibacter actinomycetemcomitans
Authors: Pourhajibagher Maryam , Bahador Abbas
Published: November 2020

Background:

Photoactivated disinfection (PAD) has been indicated as one of the potential
methods for the initial periodontal therapy in periodontitis and peri-implantitis, which may
have bystander effects on the viability of off-target cells.

Objective:

In this article, we evaluated the effects of PAD-induced bystander on biofilm formation
ability, metabolic activity, and gene expression level of Aggregatibacter actinomycetemcomitans
as one of the bacteria involved in causing periodontitis and peri-implantitis.

Methods:

Bystander effects induced by bacterial cell suspension (BCST) obtained from treated A.
actinomycetemcomitans culture with indocyanine green (ICG)-PAD on biofilm formation of A. actinomycetemcomitans
were determined using microbial viability assay. Additionally, metabolic activity
and changes in gene expression of fimA were assessed using the XTT reduction method and
quantitative real-time PCR (qRT-PCR) assay, respectively.

Results:

The results revealed that 1000 and 125 μg/mL of ICG combined with diode laser irradiation
for 1 min were significant and sub-significant reduction doses of ICG-PAD, respectively, versus
A. actinomycetemcomitans. The biofilm formation ability, metabolic activity, as well as, expression
level of fimA gene in A. actinomycetemcomitans were significantly reduced after treatment by
a significant reduction dose of ICG-PAD-induced bystander effects (P<0.05).

Conclusions:

ICG-PAD could significantly reduce the microbial population, cell metabolic activity,
and gene expression through the bystander effects and could enhance the efficiency of PAD as an
adjunct approach for the nonsurgical treatment of periodontitis and peri-implantitis.
Holistic model of the formation of requirements for freight cars on the example of the “Northern Latitudinal Railway” project
Authors: Petrov S. V. , Nazarov I. V. , Nazarov O. N.
Published: November 2020

In the context of economic integration, an important factor is increasing the efficiency of rail transport. It depends both on the quality of the transportation process as a whole and on the quality of its individual elements. It is especially worth highlighting the rolling stock, and in particular freight cars, since it is with the car along the route that labor-intensive technological operations are performed, including shunting, technical and commercial maintenance, unscheduled repairs, as well as starting and finishing operations — loading and unloading. Therefore, the efficiency of freight transportation does not depend to a small extent on the quality of cars.

In this regard, the article highlights the results of the development of a holistic model for the formation of requirements for freight cars that increase the efficiency of the transportation process, taking into account the features of specific transportation conditions. In this case, a holistic model is applied to the conditions 

for the export of freights from fields in Western Siberia along the routes of the Northern Latitudinal Railway project.

A holistic model for the formation of requirements for the cars of the Northern Latitudinal Railway includes:

• operational and functional model, containing the substantiation of the technical and economic parameters of the cars and the model of their operation ranges, taking into account the technological operations performed;

• reliability model containing justification of the reliability indicators of cars and the parameters of the system of their maintenance and repair;

• model for evaluating and confirming efficiency based on the results of calculating a complex of technical and economic indicators of cars.

The holistic model makes it possible to formulate rational requirements for cars of different levels of specialization for specific operating conditions. The model also makes it possible to predict the effects of participants in the transportation process when using cars with given characteristics in specific transportation conditions. This contributes to the use of the principles of dynamic pricing of tariffs, depending not only on the type of freight and the region, but also on the route, distance of transportation and other parameters. As a result, the advantages and competitiveness of rail transport will be provided.
Kajian reflektif: Relevansi pendidikan humanis-religius dalam menghadapi era revolusi industri 4.0
Authors: Isnaini Rohmatun Lukluk
Published: November 2020

Penelitian ini bertujuan untuk mengkaji pendidikan humanis-religius secara reflektif dalam menghadapi era revolusi industri 4.0. Data dikumpulkan dengan teknik library research (penelitian pustaka). Data yang telah terkumpul kemudian dianalisis secara kualitatif dengan pendekatan deskriptif. Analisis data dilakukan melalui pemaparan suatu pemikiran, pendapat para ahli (Ki Hajar Dewantara dan Prof. Abdurrahman Mas’ud, Ph.D.) atau fenomena yang ada dalam kehidupan masyarakat. Hasilnya menyebutkan bahwa pendidikan humanis-religius akan terus relevan dengan berbagai perubahan zaman, terutama dalam menghadapi era revolusi industri 4.0. Hal ini dikarenakan pendidikan humanis-religius merupakan dasar pondasi dalam kehidupan setiap insan untuk menjadikannya manusia yang berkarakter baik, tidak hanya untuk dirinya sendiri tetapi juga mampu bersikap humanis terhadap sesama dengan landasan agama. Sikap humanis dan religius akan dibutuhkan pada setiap masa oleh manusia, oleh karenanya melalui pendidikan humanis-religius akan ada keseimbangan antara kemajuan intelektual untuk sosial kemasyarakatan, sehingga dapat menghasilkan generasi-generasi yang berkarakter kuat secara humanis dan religius dengan segala potensi yang dimilikinya dan diorientasikan untuk kemashlahatan umat untuk meraih kebahagiaan bagi kehidupan AbstractThis research aims to examine reflective humanist-religious education in the face of the industrial revolution era 4.0. Data collected by library research techniques (library research). The collected data is then analyzed qualitatively using a descriptive approach. Data analysis is carried out through the presentation of thought, opinion of experts (Ki Hajar Dewantara and Prof. Abdurrahman Mas'ud, Ph.D.) or phenomena that exist in people's lives. The results state that humanist-religious education will continue to be relevant to the changing times, especially in the face of the industrial revolution 4.0. This is because humanist-religious education is the basic foundation in the life of every human being to make him a human with good character not only for himself but also able to be humane towards others with a religious foundation. Humanist and religious attitudes will be needed at all times by humans. Therefore, through humanist-religious education, there will be a balance between intellectual progress for social society so that it can produce generations of people who have strong human and religious characteristics with all the potential they have and are oriented to the benefit of the people to achieve happiness for life.
Effects of Tinnitus Sound Therapy Depending on Stimulating Sound
Authors: Yoo Jeeun , Ku Minseung , Choi Soon-Je , Jin In-Ki
Published: November 2020

Purpose: This study aimed to identify the effects of sound therapy according to various types of stimuli for 3 months in people with chronic tinnitus.Methods: Fifty-eight participants with chronic tinnitus based on inclusive and exclusive criteria were randomly assigned to one of the three groups: broadband noise group, nature sound group, and music sound group. Each group received sound therapy for 3 months and the level of stimulus was set to the level of the mixing point. To measure the change in participants’ tinnitus, the Korean version of the Tinnitus Primary Function Questionnaire (K-TPFQ) was used at the initial and 3-month follow-up sessions.Results: In the mixed model analysis of variance, the main effects of time were significant in almost all the K-TPFQ categories, except for the hearing category. However, the main effect of groups was not significant in most of the K-TPFQ categories, except for the sleep category. The main effects of interaction with group × time were not significant.Conclusion: The results of this study indicate that sound therapy for 3 months could be effective in the management of tinnitus. However, no difference in the effect of sound therapy according to the type of stimuli was noted. These results show that sound therapy could be an effective method for people with tinnitus, regardless of the type of stimulus.
Apuestas del departamento de Sucre en sectores Agroindustria y Minería
Authors: Arroyo Morales Eylen , Mendoza Ortega Gean Pablo , Hernández Guillermo Carlos , Vergara rodríguez César José , Puentes Márquez Jorge , Vergara Narváez Andrés , Hernández Ruiz Moisés , Vásquez Otálora César Augusto , Vergara Streinesberger Francisco , Hernández Meza Yuraima Yuliza , Martínez Franco Jaime Alberto , Martínez García José de la Concepción , Pérez Fernández Angelly Paola , Navarro Mesa Clarisa Isabel
Published: November 2020

El libro “Apuestas del Departamento de Sucre en sectores Agroindustria y Minería” es un aporte desde la academia y la ciencia para dar soluciones ante las necesidades del Departamento. La importancia que representa el desarrollo económico, productivo y social desde estos ámbitos para el territorio contribuye a procesos de cambio, crecimiento y mejoras en las condiciones de vida de sus habitantes. Es de esta manera, como los autores de esta publicación responden con sus investigaciones a dar respuestas objetivas a las necesidades actuales más sentidas del departamento de Sucre.
A Mindfulness-Based Brain-Computer Interface to Augment Mandala Coloring for Depression: Protocol for a Single-Case Experimental Design
Authors: Daudén Roquet Claudia , Sas Corina
Published: November 2020

Background

The regular practice of mindfulness has been shown to provide benefits for mental well-being and prevent depression relapse. Technology-mediated interventions can facilitate the uptake and sustained practice of mindfulness, yet the evaluation of interactive systems, such as brain-computer interfaces, has been little explored.

Objective

The objective of this paper is to present an interactive mindfulness-based technology to improve mental well-being in people who have experienced depression. The system, Anima, is a brain-computer interface that augments mandala coloring by providing a generative color palette based on the unfolding mindfulness states during the practice. In addition, this paper outlines a multiple-baseline, single-case experimental design methodology to evaluate training effectiveness.

Methods

Adult participants who have experienced depression in the past, have finished treatment within the last year, and can provide informed consent will be able to be recruited. The Anima system, consisting of 2 tablets and a nonintrusive mental activity headband, will be delivered to participants to use during the study. Measures include state and trait mindfulness, depression symptoms, mental well-being, and user experience, and these measures will be taken throughout the baseline, intervention, and monitoring phases. The data collection will take place in the form of a questionnaire before and after each mandala-coloring session and a semistructured interview every 2 weeks. Trial results will be analyzed using structured visual analysis, supplemented with statistical analysis appropriate to single-case methodology.

Results

Study results will offer new insights into the deployment and evaluation of novel interactive brain-computer interfaces for mindfulness training in the context of mental health. Moreover, findings will validate the effectiveness of this training protocol to improve the mental well-being of people who have had depression. Participants will be recruited locally through the National Health Service.

Conclusions

Evidence will assist in the design and evaluation of brain-computer interfaces and mindfulness technologies for mental well-being and the necessary services to support people who have experienced depression.

International Registered Report Identifier (IRRID)

PRR1-10.2196/20819
Use of an Internet-of-Things Smart Home System for Healthy Aging in Older Adults in Residential Settings: Pilot Feasibility Study (Preprint)
Authors: Choi Yong K , Thompson Hilaire J , Demiris George
Published: November 2020

BACKGROUND

The Internet-of-Things (IoT) technologies can create smart residences that integrate technology within the home to enhance residents’ safety as well as monitor their health and wellness. However, there has been little research on real-world testing of IoT smart home devices with older adults, and the feasibility and acceptance of such tools have not been systematically examined.

OBJECTIVE

This study aims to conduct a pilot study to investigate the feasibility of using IoT smart home devices in the actual residences of older adults to facilitate healthy aging.

METHODS

We conducted a 2-month feasibility study on community-dwelling older adults. Participants chose among different IoT devices to be installed and deployed within their homes. The IoT devices tested varied depending on the participant’s preference: a door and window sensor, a multipurpose sensor (motion, temperature, luminosity, and humidity), a voice-operated smart speaker, and an internet protocol (IP) video camera.

RESULTS

We recruited a total of 37 older adults for this study, with 35 (95%) successfully completing all procedures in the 2-month study. The average age of the sample was 78 (SD 9) years and primarily comprised women (29/37, 78%), those who were educated (31/37, 86%; bachelor’s degree or higher), and those affected by chronic conditions (33/37, 89%). The most widely chosen devices among the participants were multipurpose sensors and smart speakers. An IP camera was a significantly unpopular choice among participants in both phases. The participant feedback suggests that perceived privacy concerns, perceived usefulness, and curiosity to technology were strong factors when considering which device to have installed in their home.

CONCLUSIONS

Overall, our deployment results revealed that the use of IoT smart home devices is feasible in actual residences of older adults. These findings may inform the follow-up assessment of IoT technologies and their impact on health-related outcomes and advance our understanding of the role of IoT home-based monitoring technologies to promote successful aging-in-place for older adults. Future trials should consider older adults’ preferences for the different types of smart home devices to be installed in real-world residential settings.
Association between Use of Hydrochlorothiazide and Risk of Keratinocyte Cancers in Kidney Transplant Recipients
Authors: Letellier Thibault , Leborgne Florent , Kerleau Clarisse , Gaultier Aurélie , Dantal Jacques , Ville Simon ,   on behalf of Divat Consortium
Published: November 2020

Background and objectives

Keratinocyte cancers, which primarily comprise squamous cell carcinomas and basal cell carcinomas, represent a major concern and potential risk for kidney transplant recipients. Hydrochlorothiazide, a diuretic widely used to treat hypertension, has been implicated in skin photosensitivity reaction. Recent studies conducted in the general population have found that hydrochlorothiazide use is associated with a higher risk of keratinocyte cancer, especially squamous cell carcinomas. High-risk groups, however, including transplant recipients were excluded from these. Our aim was to investigate whether hydrochlorothiazide use was associated with keratinocyte cancer in kidney transplant recipients on immunosuppressive therapy.

Design, setting, participants, & measurements

In a single-center cohort of kidney (n=2155), combined kidney-pancreas (n=282), and pancreas (n=59) transplant recipients from the Données Informatisées VAlidées Transplantation (DIVAT) database transplanted between 2000 and 2017 in Nantes, France, we evaluated the association between hydrochlorothiazide exposure and keratinocyte cancers. Multivariable cause-specific, time-varying Cox models were used to estimate the relationship between hydrochlorothiazide exposure and the hazard of squamous cell carcinoma and basal cell carcinoma, with hydrochlorothiazide designated as the time-dependent variable.

Results

Among the participants, 279 of 2496 (11%) were exposed to hydrochlorothiazide after the transplantation. Cumulative incidence rates of keratinocyte cancer by 10 and 15 years were 7% and 9% for squamous cell carcinomas, respectively, and 8% and 11% for basal cell carcinomas, respectively. We found a relationship between exposure to hydrochlorothiazide and the risk of squamous cell carcinomas (hazard ratio, 2.04; 95% confidence interval, 1.27 to 3.28). In contrast, we found no association between hydrochlorothiazide exposure and basal cell carcinomas (hazard ratio, 0.63; 95% confidence interval, 0.35 to 1.15).

Conclusions

In a single-center cohort of kidney, combined kidney-pancreas, and pancreas transplant recipients, exposure to hydrochlorothiazide was associated with a two-fold higher risk of squamous cell carcinoma and no higher risk of basal cell carcinoma.
Characterizing Opportunity Power in the California Independent System Operator (CAISO) in Years 2015-2017
Authors: Chien Andrew A.
Published: November 2020

Studying the California Independent System Operator (CAISO) day-ahead and real-time markets for the period January 2015 to December 2017, we characterize the growth of curtailment and negative-priced power from renewable generators. Results show that renewable curtailment is growing rapidly, tripling to over 400 GWh from 2015-2018. Negative-priced renewable power is larger and also growing rapidly, reaching 1.5 TWh in 2017 for 40% CAGR.Resource-hours for negative pricing grew nearly 3-fold from 80,006 to 217,728 hours, with the highest single generator reaching 955 hours in 2017 or 33% of the daylight solar hours. Spatially, the quantity of negative-priced power is concentrated at a few dozen renewable generators, reaching peaks of 170GWh at the largest generator. We also consider an averaged-price model (NetPrice) that smooths over fluctuations to estimate the usable quantities of low-priced power. Results for NetPrice show a much larger quantity of low-priced power available than with either negative-pricing or curtailment alone. Overall, these results suggest both that opportunity power is a substantial and growing resource and a number of opportunities to exploit it.
Репрессии против комсомола Калмыкии во 2-й половине 1930-х гг.
Authors:   Kalmyk Scientific Center of the RAS, Okonov Baatr A.
Published: November 2020

Introduction. The paper deals with repressions against Kalmykia’s Komsomol in the late 1930. It examines archival materials of the Kalmyk ASSR, and explores a definitely troubled period in the development of the regional organization of All-Union Leninist Young Communist League. From the earliest days Komsomol communities had been regularly cleansed. In official discourse, such measures were interpreted as essentials aimed to exclude unreliable individuals, improve community cohesion, and facilitate further Socialist construction activities. According to documents issued by the 4th Plenary Assembly of Komsomol Central Committee and 14th Kalmyk Oblast Komsomol Conference, those were Komsomol executives and activists who were actually repressed. Goals. The article aims to analyze the repressive procedures initiated. Materials and Methods. Considered are unpublished documents held by National Archive of Kalmykia (Collection П-22 — archives of Kalmyk Oblast Komsomol Committee), and some other published materials. The work employs the chronological and problem-chronological research methods that proved instrumental in identifying features specific for repressive measures against local Komsomol members. Results and Conclusions. The 1930s political repressions against Komsomol in Kalmykia were directly related to ones against party-state and economic executives of the region. Admitting to ‘have participated in a bourgeois-nationalist organization’, Communist and Komsomol executives gave rise to further mass and dramatic cleanses.
Prediction for civil aero-engine performance after shop visit based on lazy support vector machine regression model
Authors: Fu Xuyun , Zhou Xingjie , Zhong Shisheng
Published: November 2020

Through consideration of problems that the influence of the aero-engine state before shop visit and the adopted maintenance work scope on its performance after shop visit is complex and the sample size is small, we propose a lazy support vector machine regression (LSVMR) model for aero-engine performance prediction after shop visit based on the ε-support vector machine regression (ε-SVMR) model. Unlike the ε-SVMR, the insensitive loss function in LSVMR depends on the distance between the training sample and the predicted sample. The proposed model not only makes full use of the information of the predicted sample, but also seeks the best tradeoff between the model complexity and the learning ability. In this article, we give the solving process of LSVMR and collect the actual aero-engine maintenance samples from an airline to validate it. By comparing the prediction accuracy among LSVMR, ε-SVMR and k-nearest neighbor algorithm (k-NN), we find that LSVMR has the best prediction accuracy and can be seen as an effective method for the aero-engine performance prediction after shop visit.
Health Monitoring of IGBTs with a Rule-Based Sub-safety Recognition Model Using Neural Networks
Authors: Meng Linghui , Pecht Michael , Liu Jie , Wang Yuanhang , Cheng Keqiang
Published: November 2020

IGBTs are used everywhere ranging from aerospace, to transportation systems to the grid but it’s the most fragile device in power electronics. So it’s very critical to evaluate the health state and take advanced and active maintenance measures to avoid the accidents. This paper develops a rule-based sub-safety recognition model using neural networks to evaluate the degradation degree of the IGBTs and determine the health state. The model was validated with two groups of experimental data.
Penggunaan Strategi Kooperatif Model Group Investigation Bagi Siswa yang Mengalami Attention Devicit Hyperactive Disorder (ADHD)
Authors: Septiana Nila Zaimatus , Chuluq Chusnul , Ummah Choiru Umatin
Published: November 2020

Penelitian ini bertujuan untuk menguji seberapa efektifnya penerapan strategi kooperatif model Group Investigation bagi siswa yang mengalami ADHD khususnya di kelas III-B MI Nizhamiyah Rejoagung, Ploso, Jombang. Penelitian ini menggunakan metode kualitatif dengan desain studi kasus yang menggunakan dua fase dalam penerapannya. Pengambilan subjek penelitian ini menggunakan teknik purposive sampling yakni subjek yang memiliki karakteristik penderita ADHD. Penderita ADHD kerap sekali mengalami kesulitan konsentrasi (inatensi), pengendalian diri (impulsifitas), dan hiperaktifitas. Setelah menerapkan strategi kooperatif model group investigation pada siswa tersebut dengan menggunakan dua fase, menghasilkan kesimpulan bahwa pada fase pertama sampai kedua berhasil membuat penderita ADHD fokus pada tugas dan mengurangi perilaku berlebihannya.
Podem ser considerados protestantes os batistas?
Authors: Stephanini Valdir , Brotto Julio Cezar de Paula
Published: November 2020

Neste momento em que são comemorados os 500 anos da Reforma Protestante, o presente artigo argumentará sobre a impossibilidade de se comprovar historicamente as origens dos batistas de forma dissociada do pensamento e dos pressupostos da Reforma. Para tanto serão apresentadas as principais teorias sobre as origens dos batistas, a saber: a teoria sucessionista orgânica estrita; a teoria do parentesco anabatista; a teoria do sucessionismo espiritual e a teoria separatista britânica. Apoiado nos argumentos históricos que podem ser verificáveis, o artigo propõe que os batistas, enquanto designados por esse nome distintivo, estão vinculados ao movimento da Reforma em função de importantes doutrinas da Reforma, como a justificação pela fé, a autoridade da Escritura e o sacerdócio universal dos crentes, afirmadas claramente na teologia batista.
Teologia do reconhecimento: provocações decoloniais e a ética do Bem Comum
Authors: Cunha Carlos Alberto Motta
Published: November 2020

Nosso objetivo é propor uma intelecção da fé em perspectiva decolonial, que aqui chamamos de “teologia do reconhecimento”. Ou seja, repensar não só a epistemologia da teologia, mas também sua tarefa, iluminadas pela situação de colonização dos excluídos. Esse húmus de reflexão também permite avaliar criticamente os interesses por trás de uma teologia hegemônica propiciando, como sugere Juan Luis Segundo, a libertação da própria teologia. Para isso, faremos uma breve introdução sobre a situação de intolerância, tolerância e reconhecimento na atualidade, para, no segundo momento, avaliar criticamente as provocações decolonias à teologia e, por fi m, propor uma intelecção da fé disposta a “ouvir” o grito dos excluídos e com eles refazer a tarefa teológica a luz da ética do Bem Comum. O caminho proposto permite uma formação teológica em diálogo com as teorias decoloniais e capaz de abraçar horizontes mais amplos, reconhecendo as minorias e sua importância não só para a teologia, mas para a construção de outro mundo possível.
Religião e violência nos limites da experiência humana: um diálogo com Edward Schillebeeckx
Authors: Rocha Abdruschin Schaeffer , Rosa Wanderley Pereira da
Published: November 2020

O presente artigo propõe-se a refletir sobre os limites da relação entre religião e violência tendo como referência principal o teólogo belga Edward Schillebeeckx. Com isso em foco, sugere a violência como algo que não necessariamente tem na religião sua origem, bem como procura mostrar que a religião também não pode ser atrelada automaticamente à violência ou mesmo à não violência. Seu ponto de partida é a conceituação de essencialismo, aplicado tanto à religião como à violência, uma vez que, conforme o ponto de vista dos autores, a categoria de análise essencialista fundamenta uma equivocada e apressada relação entre esses dois entes.