bluuebunny/crossref_metadata_2025 huggingface dataset:
EEG-based Brain-Computer Interfaces for people with Disorders of Consciousness: Features and applications. A systematic review
Authors: Galiotta Valentina , Quattrociocchi Ilaria , D'Ippolito Mariagrazia , Schettini Francesca , Aricò Pietro , Sdoia Stefano , Formisano Rita , Cincotti Febo , Mattia Donatella , Riccio Angela
Published: December 2022

Background

Disorders of Consciousness (DoC) are clinical conditions following a severe acquired brain injury (ABI) characterized by absent or reduced awareness, known as coma, Vegetative State (VS)/Unresponsive Wakefulness Syndrome (VS/UWS), and Minimally Conscious State (MCS). Misdiagnosis rate between VS/UWS and MCS is attested around 40% due to the clinical and behavioral fluctuations of the patients during bedside consciousness assessments. Given the large body of evidence that some patients with DoC possess “covert” awareness, revealed by neuroimaging and neurophysiological techniques, they are candidates for intervention with brain-computer interfaces (BCIs).

Objectives

The aims of the present work are (i) to describe the characteristics of BCI systems based on electroencephalography (EEG) performed on DoC patients, in terms of control signals adopted to control the system, characteristics of the paradigm implemented, classification algorithms and applications (ii) to evaluate the performance of DoC patients with BCI.

Methods

The search was conducted on Pubmed, Web of Science, Scopus and Google Scholar. The PRISMA guidelines were followed in order to collect papers published in english, testing a BCI and including at least one DoC patient.

Results

Among the 527 papers identified with the first run of the search, 27 papers were included in the systematic review. Characteristics of the sample of participants, behavioral assessment, control signals employed to control the BCI, the classification algorithms, the characteristics of the paradigm, the applications and performance of BCI were the data extracted from the study. Control signals employed to operate the BCI were: P300 (N = 19), P300 and Steady-State Visual Evoked Potentials (SSVEP; hybrid system, N = 4), sensorimotor rhythms (SMRs; N = 5) and brain rhythms elicited by an emotional task (N = 1), while assessment, communication, prognosis, and rehabilitation were the possible applications of BCI in DoC patients.

Conclusion

Despite the BCI is a promising tool in the management of DoC patients, supporting diagnosis and prognosis evaluation, results are still preliminary, and no definitive conclusions may be drawn; even though neurophysiological methods, such as BCI, are more sensitive to covert cognition, it is suggested to adopt a multimodal approach and a repeated assessment strategy.
Effects of constraint-induced movement therapy on activity and participation after a stroke: Systematic review and meta-analysis
Authors: de Azevedo Joyce Araújo , Barbosa Felipe Douglas Silva , Seixas Valquiria Martins , da Silva Scipioni Kelly Regina Dias , Sampaio Priscila Yukari Sewo , da Cruz Daniel Marinho Cezar , Piscitelli Daniele , Chui Kevin K. , de Freitas Zanona Aristela
Published: December 2022

Introduction

Hemiparesis is the main sensorimotor deficit after stroke. It can result in limitations in Activities of Daily Living (ADL) and social participation. Hemiparesis can be treated with behavioral techniques of intensive use of the affected arm, such as constraint-induced movement therapy (CIMT), however, it remains unclear whether motor improvement can lead to increases in the domains of activity and participation.

Objective

Identify whether CIMT is superior to usual techniques to enhance activity and participation outcomes in stroke survivors.

Methods

A systematic review with meta-analysis was conducted, based on the PRISMA guidelines. Search databases were: PubMed, LILACS, Embase, SciELO, Cochrane Library, Scopus, Medline, and Web of Science, with no language restriction. Meta-analysis was performed with Review Manager (version 5.3), significance level p ≤ 0.05.

Results

A total of 21 articles were included for analysis. Superior effects were observed on motor function and performance in activities of daily living of individuals treated with CIMT. The outcomes measures utilized were: Fugl-Meyer Assessment (p = 0.00001); Wolf motor function test (p = 0.01); Modified Barthel Index (p = 0.00001); Motor Activity log (MAL) Amount of use (AOU) (p = 0.01); MAL Quality of movement (QOM) (p = 0.00001); Action Research Arm Test-ARAT (p = 0.00001); and FIM (p = 0.0007).

Conclusion

Our results show that CIMT results in more significant gains in the functional use of the upper limb in ADL and functional independence, demonstrating superior activity and participation results in stroke survivors when compared to conventional therapies.
Real-time qPCR for the detection of puffer fish components from Lagocephalus in food: L. inermis, L. lagocephalus, L. gloveri, L. lunaris, and L. spadiceus
Authors: Yin Xinying , Xing Ranran , Li Zhiru , Hu Bing , Yang Lili , Deng Ruijie , Cao Jijuan , Chen Ying
Published: December 2022

Puffer fish is a type of precious high-end aquatic product, is widely popular in Asia, especially in China and Japan, even though it naturally harbors a neurotoxin known as tetrodotoxin (TTX) that is poisonous to humans and causes food poisoning. With the increasing trade demand, which frequently exceeds existing supply capacities, fostering fraudulent practices, such as adulteration of processed products with non-certified farmed wild puffer fish species. To determine the authenticity of puffer fish processed food, we developed a real-time qPCR method to detect five common puffer fish species in aquatic products: Lagocephalus inermis, Lagocephalus lagocephalus, Lagocephalus gloveri, Lagocephalus lunaris, and Lagocephalus spadiceus. The specificity, cross-reactivity, detection limit, efficiency, and robustness of the primers and probes created for five species of puffer fish using TaqMan technology have been determined. No cross-reactivity was detected in the DNA of non-target sample materials, and no false-positive signal was detected; the aquatic products containing 0.1% of a small amount of wild puffer fish materials without certification can be reliably tracked; the statistical p-value for each method’s Ct value was greater than 0.05. The developed qPCR method was sensitive, highly specific, robust, and reproducibility, which could be used to validate the authenticity of wild puffer fish in aquatic products sold for commercial purposes.
Advances in Polygonatum sibiricum polysaccharides: Extraction, purification, structure, biosynthesis, and bioactivity
Authors: Liu Dan , Tang Wei , Han Chao , Nie Shaoping
Published: December 2022

Polygonatum sibiricum has been used as food and medicine for thousands of years, and P. sibiricum polysaccharides (PSPs) have become the hot research spot due to their various health-promoting functions. Numerous studies have shown that PSPs possess huge potential in the application of functional food and medicine fields. However, the research status and features of the preparation process, molecular structure, and bioactivities of PSPs are unclear. Therefore, this review makes a comprehensive summary and proposes new insights and guidelines for the extraction, purification, structural features, biosynthesis, and multiple bioactivities of PSPs. Notably, it is concluded that PSPs mainly contain several types of polysaccharides, including fructan, pectin, galactomannan, glucomannans, arabinogalactan, and galactan, and multiple bioactivates, including osteogenic activity, anti-obesity, anti-diabetes, anti-depression, antioxidant, antiglycation, and protective effect against neurotoxicity and gut microbiota regulating activity. This review contributes to the structure–function study and resource utilization of P. sibiricum and its polysaccharides in food fields.
Combination of immune checkpoint inhibitors with radiation therapy in cancer: A hammer breaking the wall of resistance
Authors: Voronova Veronika , Vislobokova Anastasia , Mutig Kerim , Samsonov Mikhail , Peskov Kirill , Sekacheva Marina , Materenchuk Maria , Bunyatyan Natalya , Lebedeva Svetlana
Published: December 2022

Immuno-oncology is an emerging field in the treatment of oncological diseases, that is based on recruitment of the host immune system to attack the tumor. Radiation exposure may help to unlock the potential of the immune activating agents by enhancing the antigen release and presentation, attraction of immunocompetent cells to the inflammation site, and eliminating the tumor cells by phagocytosis, thereby leading to an overall enhancement of the immune response. Numerous preclinical studies in mouse models of glioma, murine melanoma, extracranial cancer, or colorectal cancer have contributed to determination of the optimal radiotherapy fractionation, as well as the radio- and immunotherapy sequencing strategies for maximizing the antitumor activity of the treatment regimen. At the same time, efficacy of combined radio- and immunotherapy has been actively investigated in clinical trials of metastatic melanoma, non-small-cell lung cancer and renal cell carcinoma. The present review summarizes the current advancements and challenges related to the aforementioned treatment approach.
Computed tomography angiography assessment of the degree of simple coarctation of the aorta and its relationship with surgical outcome: A retrospective analysis
Authors: Xiao Hui-Jun , Zhan A-Lai , Huang Qing-Wen , Huang Rui-Gang , Lin Wei-Hua
Published: December 2022

Objective

To investigate the correlation between the degree of aortic coarctation and surgical prognosis in infants with simple coarctation of the aorta (CoA) using computed tomography angiography (CTA).

Methods

This study was a retrospective study. Twenty-seven infants with simple CoA who underwent surgical correction from January 2020 to June 2022 were enrolled. Aortic diameters were measured at five different levels and normalized to Z scores based on the square root of body surface area. The relevant data were collected and analyzed, and the predictors associated with surgical outcome were determined.

Results

Patients were divided into the mild CoA group and the severe CoA group according to the severity of coarctation. The mechanical ventilation duration and the length of ICU stay in the mild CoA group were significantly lower than those in the severe CoA group. Multiple linear regression analyses revealed that the degree of aortic coarctation was a significant risk factor for a prolonged postoperative ICU stay. In addition, gestational age and age at operation were risk factors for a prolonged postoperative ICU stay. Correlation analysis showed that the degree of aortic coarctation correlated with the Z scores of the ascending aorta and postcoarctation aorta.

Conclusion

The degree of the CoA is an important predictor of surgical outcomes in infants with simple CoA and was significantly correlated with the ascending aorta and postcoarctation aorta Z scores. Therefore, preoperative CTA should be routinely performed to assess the degree of aortic coarctation and better identify risk factors.
Plasma cell free next-generation sequencing detects an unusual pneumonia pathogen in an immunocompetent adolescent with acute respiratory distress syndrome
Authors: Rodriguez Katherine M. , Ramchandar Nanda , Coufal Nicole G.
Published: December 2022

This case details a rapid diagnosis of legionella pneumonia causing severe acute respiratory distress syndrome (ARDS) in an otherwise healthy adolescent through plasma microbial cell-free DNA next generation sequencing (mcfDNA-NGS). Diagnosis by mcfDNA-NGS of this unexpected pathogen led to narrowing of antimicrobials and the addition of glucocorticoids as adjunctive therapy for ARDS.
Case Report: Interventional therapy for coronary artery occlusion in a 6-year-old child with Kawasaki disease
Authors: Zhao Lu , Xie Li-ping , He Lan , Liang Xue-cun , Chu Chen , Liu Fang
Published: December 2022

A 6-year-old girl was diagnosed with Kawasaki disease and bilateral giant coronary artery aneurysms at four months old and was subsequently referred to our hospital due to chest pain and T wave changes on electrocardiography. After admission, stress myocardial perfusion imaging showed reversible ischemia in multiple areas of the left ventricle. Coronary angiography revealed complete proximal segment occlusion of the left circumflex artery (LCX). The occluded LCX was recanalized by a Gaia 3rd micro-wire successfully passing through the occluded section to the distal end of the LCX, followed by sequential balloon dilation and drug-coated balloon angioplasty. Coronary angiography immediately after post-dilation and one-year follow-up angiography showed that the structure and blood flow of LCX was good. Although percutaneous coronary intervention (PCI) in pediatric patients with Kawasaki disease is limited in practice, PCI remains one of the treatment options for selected patients.
Ceftriaxone-induced cholestatic hepatitis in a child: A case report and a review of the literature
Authors: Castellazzi Massimo Luca , Agostoni Carlo Virginio , Palella Jessica , Civeriati Daniela , Marchisio Paola , Nebbia Gabriella
Published: December 2022

Ceftriaxone, a third-generation cephalosporin, is commonly used in pediatric patients and is generally well tolerated. Its more frequent adverse effects are biliary pseudolithiasis, urolithiasis, and hemolytic anemia. On the other hand, ceftriaxone-induced acute cholestatic hepatitis is a very rare condition, especially in children. Here, we describe a case of this condition in a young male child to highlight the importance of suspecting this drug-induced liver injury to achieve a prompt diagnosis.
Clinical characteristics, pathology features and outcomes of pediatric myeloid sarcoma: A retrospective case series
Authors: Ye Fanghua , Zhang Hui , Zhang Wen , Dong Jiajia , Deng Wenjun , Yang Liangchun
Published: December 2022

Purpose

Myeloid sarcoma (MS) is a rare extramedullary mass with myeloid expression, which is easy to be missed and misdiagnosed, especially in the pediatric population. We analyze the clinicopathological characteristics, immunophenotypic, cytogenetic, and molecular studies, therapeutic approaches, and outcomes, to optimize the management of such patients.

Methods

A retrospective, single-center, case series study of eleven children diagnosed with MS by pathology was performed.

Results

The male-to-female ratio was 8:3, and the median age at diagnosis was 7 years. The most commonly involved sites were the skin and orbital region, followed by lymph nodes, central nervous system, and testis. Seven cases (64%) with Class I-MS and four cases (36%) presented as Class II-MS. Immunohistochemically, MPO and CD117 were the most commonly expressed markers, followed by CD33, CD43, CD34, CD68, and lysozyme. Chromosomal abnormalities were detected in 4 patients. Two patients had the presence of deleterious mutations (FLT3, ASXL, KIT, and DHX15) on molecular detection. Ten patients were treated with chemotherapy based on AML regimens. The median follow-up time was 33.5 months in eleven patients. Two patients relapsed, one died, and one lost to follow-up. The 2-year overall survival (OS) rate estimated by Kaplan-Meier curves was 90.9% ± 8.7%, and the event-free survival (EFS) rate was 64.9% ± 16.7%.

Conclusions

MS diagnosis is usually challenging. Adequate tumor biopsy and expanded immunohistochemistry are necessary for the correct diagnosis of MS. Early and regular systemic chemotherapy promises long-term survival.
Pseudo-rheumatic manifestations of limping: Camptodactyly–arthropathy–coxa vara–pericarditis syndrome: Single case report and review of the literature
Authors: Maniscalco Valerio , Pizzetti Camilla , Marrani Edoardo , Perrone Anna , Maccora Ilaria , Pagnini Ilaria , Artuso Rosangela , Simonini Gabriele , Mastrolia Maria Vincenza
Published: December 2022

Camptodactyly–arthropathy–coxa vara–pericarditis (CACP) syndrome is a rare genetic disease characterized by tetrad camptodactyly, noninflammatory arthropathy, coxa vara deformity, and pericardial effusion. Arthropathy typically affects large joints and presents with joint swelling in the absence of other signs of inflammation. We described the case of a girl affected by CACP syndrome caused by a novel compound heterozygous variant in proteoglycan 4 gene (c.2831_2832insT; c.3892C > T) and associated with temporomandibular involvement. The patient received treatment with intra-articular hyaluronic acid injections, which presented rapid but transient improvements of pain and range of motion. A literature review of previously reported CACP patients has been performed. Of the patients. 69.2% (101 out of 146) were Middle Eastern, and 65.7% (96) were consanguineous. The median age of onset was 24 months (interquartile range of 12–36 months), and median age of diagnosis was 96 months (interquartile range of 48–156 months). Arthropathy was always present, mainly involving hips (95.2%), knees (92.4%), wrists (87.7%), elbows (79.5%), and ankles (57.5%). Camptodactyly and pericardial effusion were described, respectively, in 97.3% (142) and 15.1% (22) of patients. The main radiological findings were coxa vara (95.2%), femoral changes (64.4%), intraosseus cysts (14.4%), and bone erosion (5%). Of the patients, 32.9% (48) had received a previous juvenile idiopathic arthritis diagnosis. CACP syndrome can be easily misdiagnosed with juvenile idiopathic arthritis. A prolonged lack of response to immunosuppressive therapy associated with typical clinical and radiological features should prompt consideration of this rare syndrome.
The effect of the cyclic GMP-AMP synthase-stimulator of interferon genes signaling pathway on organ inflammatory injury and fibrosis
Authors: Liu Yuliang , Li Yihui , Xue Li , Xiao Jie , Li Pengyong , Xue Wanlin , Li Chen , Guo Haipeng , Chen Yuguo
Published: December 2022

The cyclic GMP-AMP synthase-stimulator of interferon genes signal transduction pathway is critical in innate immunity, infection, and inflammation. In response to pathogenic microbial infections and other conditions, cyclic GMP-AMP synthase (cGAS) recognizes abnormal DNA and initiates a downstream type I interferon response. This paper reviews the pathogenic mechanisms of stimulator of interferon genes (STING) in different organs, including changes in fibrosis-related biomarkers, intending to systematically investigate the effect of the cyclic GMP-AMP synthase-stimulator of interferon genes signal transduction in inflammation and fibrosis processes. The effects of stimulator of interferon genes in related auto-inflammatory and neurodegenerative diseases are described in this article, in addition to the application of stimulator of interferon genes-related drugs in treating fibrosis.
Targeting cancer-related inflammation with non-steroidal anti-inflammatory drugs: Perspectives in pharmacogenomics
Authors: Lai Hongjin , Liu Yi , Wu Juan , Cai Jie , Jie Hui , Xu Yuyang , Deng Senyi
Published: December 2022

Inflammatory processes are essential for innate immunity and contribute to carcinogenesis in various malignancies, such as colorectal cancer, esophageal cancer and lung cancer. Pharmacotherapies targeting inflammation have the potential to reduce the risk of carcinogenesis and improve therapeutic efficacy of existing anti-cancer treatment. Non-steroidal anti-inflammatory drugs (NSAIDs), comprising a variety of structurally different chemicals that can inhibit cyclooxygenase (COX) enzymes and other COX-independent pathways, are originally used to treat inflammatory diseases, but their preventive and therapeutic potential for cancers have also attracted researchers’ attention. Pharmacogenomic variability, including distinct genetic characteristics among different patients, can significantly affect pharmacokinetics and effectiveness of NSAIDs, which might determine the preventive or therapeutic success for cancer patients. Hence, a more comprehensive understanding in pharmacogenomic characteristics of NSAIDs and cancer-related inflammation would provide new insights into this appealing strategy. In this review, the up-to-date advances in clinical and experimental researches targeting cancer-related inflammation with NSAIDs are presented, and the potential of pharmacogenomics are discussed as well.
Data needs to be a priority
Authors: Halford Alexa J. , Chen Thomas Y. , Rastaetter Lutz
Published: December 2022

Findability, Accessibility, Interoperability, and Reusability (FAIR) data are essential to heliophysics and all scientific research. The principles of FAIR data ensure the reusability and findability of data, as well as its long-term care. The goal is that data are accessible for the ongoing discovery and verification process and can be used on their own or with newly generated data in future studies leading to innovations. With the onset in the previous decades of NASA and other agencies requiring mission data to be open to the public, heliophysics has already made great strides toward FAIR data and benefited from these efforts. Continued improvements in our metadata, data archives, and data portals and the addition of DOIs for data citation will ensure data will be FAIR, enabling further scientific discoveries, reproducibility of results, longitudinal studies, and verification and validation of models. Currently, not all the data collected are findable and on open networks or archives, and not all data on archives have DOIs. Within this study, we make recommendations to prioritize resources needed to satisfy FAIR data principles, treating them as a fundamental research infrastructure rather than a simple research product.• Data collection, preparation, archiving, and accessibility need to be a priority.• Data collection, preparation, archiving, and accessibility need dedicated and sustained funding support.• Data need to be accessible through investment in infrastructure: tools to access and read the data and personnel to maintain these data and IT infrastructure.• Data need to be collected in sustained ways to enable further science and, specifically, model validation efforts.
A survey of highly cited studies on plant pathogen effectors during the last two decades (2000-2020)
Authors: Louet Clémentine , Duplessis Sébastien , Frey Pascal , Petre Benjamin
Published: December 2022

Plant effector biology is a research area that describes how plant-associated organisms modulate host structures and function to promote colonization by using small molecules (effectors). In this article, we analyzed 249 highly cited publications focused on plant pathogen effectors (i.e., Highly Influential studies on plant Pathogen Effectors; thereafter HIPEs) published between 2000 and 2020. This analysis identifies countries, organizations, and journals that contributed HIPEs, and reveals the evolution of research trends, model molecules, and model organisms over the last two decades. We notably show an increasing proportion of studies focused on effectors of biotrophic and hemibiotrophic fungi upon time. Our snapshot of the highly influential plant effector biology papers may help new comers in the field to gain an analytical understanding of this research area.
Genome-wide association study reveals novel genomic regions governing agronomic and grain quality traits and superior allelic combinations for Basmati rice improvement
Authors: Abhijith Krishnan P. , Gopala Krishnan S. , Ravikiran Kuram Tirumala , Dhawan Gaurav , Kumar Pankaj , Vinod Kunnummal Kurungara , Bhowmick Prolay Kumar , Nagarajan Mariappan , Seth Rakesh , Sharma Ritesh , Badhran Sourav Kumar , Bollinedi Haritha , Ellur Ranjith Kumar , Singh Ashok Kumar
Published: December 2022

Background

Basmati is a speciality segment in the rice genepool characterised by explicit grain quality. For the want of suitable populations, genome-wide association study (GWAS) in Basmati rice has not been attempted.

Materials

To address this gap, we have performed a GWAS on a panel of 172 elite Basmati multiparent population comprising of potential restorers and maintainers. Phenotypic data was generated for various agronomic and grain quality traits across seven different environments during two consecutive crop seasons. Based on the observed phenotypic variation, three agronomic traits namely, days to fifty per cent flowering, plant height and panicle length, and three grain quality traits namely, kernel length before cooking, length breadth ratio and kernel length after cooking were subjected to GWAS. Genotyped with 80K SNP array, the population was subjected to principal component analysis to stratify the underlying substructure and subjected to the association analysis using Bayesian-information and Linkage-disequilibrium Iteratively Nested Keyway (BLINK) model.

Results

We identified 32 unique MTAs including 11 robust MTAs for the agronomic traits and 25 unique MTAs including two robust MTAs for the grain quality traits. Six out of 13 robust MTAs were novel. By genome annotation, six candidate genes associated with the robust MTAs were identified. Further analysis of the allelic combinations of the robust MTAs enabled the identification of superior allelic combinations in the population. This information was utilized in selecting 77 elite Basmati rice genotypes from the panel.

Conclusion

This is the first ever GWAS study in Basmati rice which could generate valuable information usable for further breeding through marker assisted selection, including enhancing of heterosis.
What matters when examining the performance of salespersons? Analyzing the boundary conditions of personal dispositional factor
Authors: Naeem Muhammad , Shah Fayaz Ali , Kakakhel Shahid Jan , Gul Shabana
Published: December 2022

Purpose

This study intended to examine the effect of developmental and evaluative purposes of performance appraisal (PA) on job meaningfulness (JM). Furthermore, the study also aimed to assess the moderating effect of personal dispositional factors, that is, internal and external loci of control between developmental and evaluative PA and JM.

Design/Methodology/Approach

A total of 295 questionnaires were received from salespersons working in national and multinational pharmaceutical companies in Khyber Pakhtunkhwa, Pakistan. Data were gathered using a time lag study design using a convenience sampling technique. Data collectedviaquestionnaires were analyzed using PLS-SEM to assess measurement and structural models for testing hypotheses.

Findings

Results revealed that developmental PA significantly influenced JM, while evaluative PA failed to influence JM. Furthermore, there was a moderating effect of the external locus of control (ELOC) on the relationship between developmental PA and JM, while the rest of moderating hypotheses failed to influence the relationship of developmental and evaluative PA with JM.

Practical implications

The results can be used as a building block in order to bring positive work outcomes in the form of meaningful work. Organizations should use their PA as a development tool, instead of instrumental or evaluative PA, for making the work more meaningful to the employees.

Originality/Value

The extant literature is limited in terms of assessing the dimensions of PA (developmental and evaluative) in predicting workplace outcomes. Also, examinations of multidimensions of the locus of control are limited in the existing literature between HR practices and work outcomes. The current study has filled these gaps in the contemporary literature.
The critical role of job embeddedness: The impact of psychological empowerment and learning orientation on organizational commitment
Authors: Yoon Dong-Yeol , Han Caleb Seung-Hyun , Lee Soo-Kyoung , Cho Jun , Sung Moonju , Han Soo Jeoung
Published: December 2022

Job embeddedness (JE) has been recognized as a key factor to address the issue of employee turnover and employee attitudes. This study explores underlying mechanisms of job embeddedness that link the organizational environment and the individuals’ perceptions of the job. Particularly, the effects of psychological empowerment and learning orientation on organizational commitment were examined. This study hypothesizes that psychological empowerment (PE) and learning orientation (LO) should influence organizational commitment (OC) and job embeddedness plays a significant mediating role in these relationships. Data were collected from 27 offices of Human Resource Development Service of Korea (governmental agency) located in major cities in South Korea. Results indicate that all hypothesized relationships (PE and JE, LO and JE, LO and OC, JE and OC, and the mediating role of JE) are supported, except for psychological empowerment and organizational commitment. While the impact of psychological empowerment was not significantly related to organizational commitment, it is notable that through job embeddedness, psychological empowerment had indirect effects on organizational commitment. Further, learning orientation had significant effects on job embeddedness and organizational commitment. Lastly, the most compelling finding is a full mediation of job embeddedness in the relationship between psychological empowerment and organization commitment. Implications for research and practice are discussed.
The influence of internet use frequency, family atmosphere, and academic performance on adolescent depression: Based on the chain mediating effect of self-adjustment and campus deviant behavior
Authors: Jiang Mao-min , Wang De-wen , Wu Zheng-yu , Gao Kai , Guo Pei-pei , Kong Yang
Published: December 2022

Introduction

Depression has become a prominent psychological problem among young people. The purpose of this study was to investigate the potential relationship between the frequency of Internet use, family atmosphere, academic performance, self-adjustment, campus deviant behavior, and depressive symptoms among adolescents.

Methods

Based on the survey data of the fifth wave (2017~2018) and the sixth wave (2019~2020) of the China Family Panel Studies (CFPS), this study used LISREL8.8 software to analyze 1,577 10~15 data on adolescents.

Results

In this study, the mean score of self-adjustment was 42.40 (SD = 6.79), the mean score of campus deviant behavior was 12.59 (SD = 4.00), the mean score of depressive symptoms in 2018 was 11.88 (SD = 3.04), and the mean score of depressive symptoms in 2020 was 7.64 (SD = 2.20). Secondly, the frequency of Internet use had no direct effect on the depressive symptoms of adolescents, family atmosphere was negatively correlated with depressive symptoms (p < 0.005), and academic performance was positively correlated with depressive symptoms (p < 0.005). Depressive symptoms in 2020 had a direct effect (β = 0.37, p < 0.001), and also had a negative effect on depressive symptoms in 2020, with a total effect of-0.07 (p < 0.001); self-adjustment had no direct effect on depressive symptoms in adolescents in 2018, However, the total effect was −0.14 (p < 0.001), which had a significant positive effect on 2020 depressive symptoms, and the total effect was 0.18 (p < 0.001), and self-adjustment had a significant negative effect on adolescent campus deviant behavior (β = −0.38, p < 0.001); in addition, the frequency of Internet use, family atmosphere, and academic performance all had indirect effects on adolescents’ 2020 depressive symptoms, with total effects of −0.60, 0.01, and 0.02 (p < 0.001), respectively. This study also found depressive symptoms in adolescents have a certain persistence in time.

Discussion

Based on this study, it is necessary to pay more attention to the depression of adolescents, strengthen the training of self-adjustment, improve the anti-frustration ability and psychological resilience, and reduce the campus deviant behavior of adolescents. It is recommended to try to start from emotional self-adjustment to promote the personality health of adolescents.
Context and target recollection for words and pictures in young adults with developmental dyslexia
Authors: Obidziński Michał , Nieznański Marek
Published: December 2022

Introduction

The specificity of memory functioning in developmental dyslexia is well known and intensively studied. However, most research has been devoted to working memory, and many uncertain issues about episodic memory remain practically unexplored. Moreover, most studies have investigated memory in children and adolescents—much less research has been conducted on adults. The presented study explored the specificity of context and target memory functioning for verbal and nonverbal stimuli in young adults with developmental dyslexia.

Methods

The dual recollection theory, which distinguishes context recollection, target recollection, and familiarity as the processes underlying memory performance in the conjoint recognition paradigm, was adopted as the theoretical basis for the analysis of memory processes. The employed measurement model, a multinomial processing tree model, allowed us to assess the individual contributions of the basic memory processes to memory task performance.

Results

The research sample consisted of 82 young adults (41 with diagnosed dyslexia). The results showed significant differences in both verbal and nonverbal memory and context and target recollection between the dyslexic and the typically developing groups. These differences are not global; they only involve specific memory processes.

Discussion

In line with previous studies using multinomial modeling, this shows that memory functioning in dyslexia cannot be characterized as a simple impairment but is a much more complex phenomenon that includes compensatory mechanisms. Implications of the findings and possible limitations are discussed, pointing to the need for further investigation of the relationship between context memory functioning and developmental dyslexia, taking into account the type of material being processed.
The economics of psychedelic-assisted therapies: A research agenda
Authors: Marseille Elliot , Bertozzi Stefano , Kahn James G.
Published: December 2022

After a long hiatus, psychiatry is undergoing a resurgence of interest in psychedelic drugs as therapy for a wide range of mental health disorders Accumulating clinical evidence suggests substantial potential for psychedelics used in a therapeutic context, as treatment for, among other disorders, depression, post-traumatic stress disorder (PTSD), and addictions to tobacco, opioids and alcohol. As soon as 2024, powerful new therapeutic modalities could become available for individuals with mental health problems refractory to traditional therapies. Yet research has lagged on economic considerations, such as costs and cost-effectiveness, the economic effects of widespread implementation, pricing, and economic appraisal's methodological considerations relevant to psychedelic therapies. These issues are critical if psychedelic therapies are to become widely accessible. We describe six types of economic analyses and their rationale for decisions and planning including the needs of health care payers. We also outline desirable features of this research, including scientific rigor, long horizons, equity, and a global view.
Impact of food safety supervision efficiency on preventing and controlling mass public crisis
Authors: Ding Jian , Qiao Ping , Wang Jiaxing , Huang Hongyan
Published: December 2022

Food safety has received unprecedented attention since the COVID-19 outbreak. Exploring food safety regulatory mechanisms in the context of cluster public crises is critical for COVID-19 prevention and control. As a result, using data from a food safety regulation survey in the Bei-jing-Tianjin-Hebei urban cluster, this paper investigates the impact of food safety regulation on the prevention and control of COVID-19. The study found that food safety regulation and cluster public crisis prevention and control have a significant positive relationship, with the ability to integrate regulatory resources acting as a mediator between the two. Second, industry groups argue that the relationship between regulatory efficiency and regulatory resource integration should be moderated in a positive manner. Finally, industry association support positively moderates the mediating role of regulatory re-source integration capacity between food safety regulatory efficiency and cluster public crises, and there is a mediating effect of being moderated. Our findings shed light on the mechanisms underlying the roles of regulatory efficiency, resource integration capacity, and industry association support in food safety, and they serve as a useful benchmark for further improving food safety regulations during the COVID-19 outbreak.
Impact of smart health systems on the behavior of older adults under community healthcare
Authors: Zhao Jing , Wang Liangyu , Guo Kaimeng
Published: December 2022

Background

With the trend of world population aging, a good community health care system will determine whether the elderly can get good medical conditions. How to improve the community health care system can study how the behavior of the elderly affects it.

Objective

This paper is based on the analysis of the current situation of population aging at home and abroad.

Methods

On the premise of analyzing the demand and behavior of elderly people seeking medical treatment and the function of community health service institutions. Literature research was conducted to analyze the influencing factors of community health care needs and elderly people's medical seeking behavior at home and abroad. Then the elderly in Tianjin were investigated by issuing questionnaires, and the law of medical treatment behavior of the elderly in Tianjin was calculated. Combined with the results of relevant investigations abroad, the common phenomenon is summarized. Finally, the analysis method of intelligent medical system is proposed, and the design process of system acquisition module and user usage mode are given.

Result

The smart medical system can bring great convenience to the elderly and community healthcare.

Discussion

It emphasizes the powerful functions of smart health systems and their future importance for the health care of the elderly.
A critical phenomenological investigation in the use of touch as “know how” in practical physiotherapy in primary care with children and adults
Authors: Bjorbækmo Wenche Schrøder , Mengshoel Anne Marit
Published: December 2022

In this article, we examine the interactions between physiotherapists and patients in actual situations, focusing on how touch is expressed, what it may mean and how physiotherapists know (or do not know) when and how to touch. The empirical material is obtained from two Norwegian research projects. In both of them, the first author observed physiotherapeutic practice and conducted interviews with patients (children and adults) and physiotherapists. A phenomenological research approach was applied, and analysis of the empirical data was guided by the concept of bridling, implying adopting a questioning attitude and being open to that which presents itself and exploring its possibilities. Three processed excerpts from the empirical data are presented to illustrate how, in different ways, physiotherapists' expert knowledge about how to relate to and interact with individual patients is put into play and expressed in real physiotherapy encounters. Each excerpt is presented individually, followed by analysis. Our findings reveal aspects of the epistemology of physiotherapeutic practice to be intercorporal and illuminated by the concept and phenomenon of letting the other be.
Greenhouse gas and energy payback times for a wind turbine installed in the Brazilian Northeast
Authors: Fonseca Luiz Felipe Souza , Carvalho Monica
Published: December 2022

Introduction

Going a step further than quantifying environmental impacts, establishing the environmental and energy payback times of a wind turbine can significantly impact the planning of a wind farm. This study applies the Life Cycle Assessment methodology to a wind turbine and verifies its environmental and energy payback times.

Methods

The Life Cycle Assessment was developed with the SimaPro software, using the Ecoinvent database and the IPCC 2013 GWP 100y and Cumulative Energy Demand environmental impact assessment methods. The Life Cycle Assessment considered the extraction of raw material, production of parts and pieces, transportation, assembly, use, and decommissioning. Besides the material composition of the wind turbine, meteorological data was also utilized to calculate wind electricity production in Northeast Brazil. The environmental analysis and data on energy production were used to calculate the time required to recoup the energy and emissions due to wind electricity compared to the emissions of the electricity grid.

Results

The emission factor of wind electricity was 0.0083 kg CO2-eq/kWh, and the emissions associated with consumption of electricity from the Brazilian Electricity mix was 0.227 kg CO2-eq/kWh. Consideration of the energy consumed for the manufacture of the wind turbine yielded an energy payback of 0.494 years, and greenhouse gas accountancy led to a payback of 0.755 years.

Discussion

The results demonstrate that the payback periods are much lower than the lifetime of the wind turbine, highlighting the important role in addressing climate change and energy savings. The combination of Life Cycle Assessment and energy and environmental paybacks can be used to measure sustainability and deploy wind energy projects in locations with the shorter payback times.
Dreaming is not enough. Audiovisual methodologies, social inclusion, and new forms of youth biopolitical resistance
Authors: Guerra Paula , Sousa Sofia
Published: December 2022

The eleventh Sustainable Development Goal, “make cities and human settlements inclusive, safe, resilient and sustainable,” can only be truly answered when there are no individuals in our societies who feel forgotten by the various social institutions. Not in Education, Employment, or Training [NEET] are among those most affected by this social invisibility. Nevertheless, these young people are not alienated or lost. Far from it. Instead, some of them found in the arts registered in the community—music, dance, photography and graffiti—a possibility to resist the various social stigmas attached on them. This was the view on which we conducted our artistic and social intervention, based on the innovative “arts-based research” methodology and “youth-led participatory research,” called “The Neighborhood is Ours II!,” with young NEETs in the socially underprivileged Cerco neighborhood of Porto in Portugal in 2022. We propose a theoretical-empirical approach around a visual/narrative sociology—namely using digital cinema—which will be based on a short film about the life narrative of a young NEET, who has used artistic practices to establish himself in the city of Porto as a cultural mediator. Thus—through these processes of co-creation of knowledge (cine-making)- we aim to demonstrate how the use of the arts can be a key tool in promoting social inclusion and reducing/minimizing feelings of insecurity, but also act as a means of resistance to the daily adversities experienced by marginalized young people and, of course, demonstrate the ways in which the use of artistic practices plays a pivotal role in the development of sustainable and alternative professional, social futures and citizenship.
Cage egg producers' perspectives on the adoption of cage-free systems in China, Japan, Indonesia, Malaysia, Philippines, and Thailand
Authors: de Luna Maria Catalina Tan , Yang Qing , Agus Ali , Ito Shuichi , Idrus Zulkifli , Iman Rahayu H. S. , Jattuchai Jutamart , Lane Elissa , Nuggehalli Jayasimha , Hartcher Kate , Sinclair Michelle
Published: December 2022

Asia is responsible for ~60% of global egg production. As in most of the world, nearly all of the egg-laying hens are housed in cages. While there is growing demand for cage-free eggs in many regions of the world, challenges have been reported when transitioning to these systems, which may affect the willingness of producers to transition. The aim of this research was to investigate the views of Asian egg producers on the feasibility of cage-free systems and what they perceive to be the main challenges and proposed solutions in adopting cage-free systems. A total of 224 egg producers (165 cage egg producers) completed questionnaires containing a mix of free-form, Likert scale and demographic items. Data were analyzed using thematic qualitative analysis and descriptive quantitative statistics. Responses indicated that cages are primarily used for their efficiency and ease of management. The most common reasons to consider adopting cage-free systems included improved animal welfare, increased market access, and increased product quality. A majority of producers (65%) responded “yes” or “maybe” when asked if they consider cage-free systems to be feasible in their country. Perceived challenges in adopting cage-free systems included reduced profitability, higher costs, and biosecurity and disease. Potential solutions included the development of the cage-free industry and market development. Most producers (72%) said more support is needed to establish cage-free farms, mostly pertaining to technical advice, training and resources. The findings of this study provide an enhanced understanding of the egg industry in these countries and potential areas for producer support in transitioning to cage-free systems.
Reentry Flight Capability Assessment Based on Dynamics–Informed Neural Network and Piecewise Guidance
Authors: Liu Kai , Zhang Jili , Guo Xinlu
Published: December 2022

To improve the flexibility of the trajectory and the diversity of the drop point of the reentry vehicle, a flight capability assessment method based on a dynamics–informed neural network (DINN) is proposed. Firstly, the concept of a reachable domain is introduced to characterize the flight capability of the reentry vehicle and to estimate whether there are appropriate TAEM points in the area. Secondly, after the impact characteristic analysis, the reachable domains corresponding to different initial flight states are obtained through moderate dynamic simulations and reasonable mathematical expansion. The flight states and boundary point positions of the reachable domain are used as the training database of DINN, and the acquired DINN can realize the fast solution of reachable domains. Finally, the effectiveness of DINN in solving the reachable domain is verified using simulation. The simulation results show that DINN manifests the same accuracy as the existing solving methods and can meet the demand of determining whether the target point is located in the reachable domain. Additionally, the running time is shortened to one–800th of the existing methods, reaching the millisecond level, to support real–time assessment and decision–making. A predictor–corrector guidance algorithm with the piecewise objective function is also introduced. The simulation results illustrate that the proposed algorithm can stably guide the vehicle from the initial state points to the target points in the reachable domain.
Malicious URL Detection Model Based on Bidirectional Gated Recurrent Unit and Attention Mechanism
Authors: Wu Tiefeng , Wang Miao , Xi Yunfang , Zhao Zhichao
Published: December 2022

With the rapid development of Internet technology, numerous malicious URLs have appeared, which bring a large number of security risks. Efficient detection of malicious URLs has become one of the keys for defense against cyber attacks. Deep learning methods bring new developments to the identification of malicious web pages. This paper proposes a malicious URL detection method based on a bidirectional gated recurrent unit (BiGRU) and attention mechanism. The method is based on the BiGRU model. A regularization operation called a dropout mechanism is added to the input layer to prevent the model from overfitting, and an attention mechanism is added to the middle layer to strengthen the feature learning of URLs. Finally, the deep learning network DA-BiGRU model is formed. The experimental results demonstrate that the proposed method can achieve better classification results in malicious URL detection, which has high significance for practical applications.