bluuebunny/crossref_metadata_2025 huggingface dataset:
A Mars-analog sulfate mineral, mirabilite, preserves biosignatures
Authors: Gill Karena K. , Jagniecki Elliot A. , Benison Kathleen C. , Gibson Martha E.
Published: June 2023

Various sulfate minerals exist on Mars; except for gypsum, they are understudied on Earth. Extremophiles have been documented in modern gypsum and halite and ancient halite, but other chemical sediments have not been evaluated for biosignatures. Here, we present the first observations and analysis of microorganisms and organic compounds in primary fluid inclusions in the Mars-analog mineral mirabilite, Na2SO4·10H2O, from Great Salt Lake, Utah, USA. Microscopy by transmitted light and ultraviolet-visible (UV-vis) light, and Raman spectroscopy, show abundant bacteria and/or Archaea, algae, fungi, diatoms, protozoa, and organic compounds such as beta-carotene. This discovery expands our current knowledge of biological materials trapped in salt and aids the search for life on Mars, both for sample selection by rover and for analyses of return samples on Earth.
Use of ctDNA in identifying an actionable BRAF mutation in stage 4 metastatic melanoma
Authors: Bennett Charlotte , Morgan Sian , Aboud Karam , Frazer Ricky Dylan
Published: June 2023

The identification of genetic variants in melanoma has enabled the development of targeted therapies. Under the National Institute for Health and Care Excellence (NICE) guidance, patients with BRAF V600E variant are eligible for BRAF and MEK inhibitor therapy. For those with advanced or highly symptomatic disease, a rapid response to treatment is often seen. Current practice relies on tissue biopsy to perform immunohistochemistry (IHC) or next generation sequencing (NGS) to identify these variants; however, this can take up to 2 weeks. In patients with widespread disease, rapid initiation of treatment can be lifesaving.

We describe a case in which hotspot circulating tumour DNA (ctDNA) analysis confirmed BRAF variant 6 days prior to biopsy results. This was utilised to expedite treatment initiation and symptomatically, the patient had initial improvement within a few days.

This article demonstrates the potential value of ctDNA analysis and the need for further research into this as an alternative to NGS for patients with rapidly progressive disease.
Enterocutaneous fistula formation after cardiac transplantation due to injury from LVAD driveline migration
Authors: Tan Derek W , Yan Crystal Lihong , Yeh Daniel Dante , Thakkar-Rivera Nina
Published: June 2023

A man in his early 20s with heart failure with reduced ejection fraction secondary to non-compaction cardiomyopathy (Titin (TTN) gene mutation positive) was transitioned from left ventricular assist device (LVAD) mechanical support to heart transplantation. Transplantation was successful; however, LVAD explantation resulted in innumerable complications secondary to penetration of the driveline into the peritoneal cavity. He developed an enterocutaneous fistula which led to concurrent malnutrition, poor wound healing, systemic infection, and allograft rejection in a patient less than 1 month after heart transplantation on immunosuppression.
Thermodynamics and phase transition of Bardeen black hole via Rényi statistics in grand canonical ensemble and canonical ensemble
Authors: Wang Zefeng , Ren Haizhen , Chen Juhua , Wang Yongjiu
Published: June 2023

The thermodynamics of the Bardeen black hole in asymptotically flat space is investigated with the corrected first law of thermodynamics via Rényi statistics. The nonextensive parameter $$\lambda $$
λ
gives the possibility to the thermal stability of Bardeen black hole, and there is a Hawking–Page phase transition in the grand canonical ensemble (fixed the potential), which is similar to the cases of Bardeen black hole and corrected Bardeen black hole in asymptotically anti-de Sitter (AdS) space via standard Gibbs–Boltzmann (GB) statistics. By introducing the general Smarr formula via Rényi statistics, the thermodynamic pressure P is defined with the parameter $$\lambda $$
λ
and its conjugate quantity V is the thermodynamic volume (not a geometric spherical volume with horizon radius $$r_{h}$$

r
h

). The thermodynamics of the asymptotically flat Bardeen black hole via Rényi statistics in the canonical ensemble (fixed the charge q) behaves like the van der Waals system, which is also same as the asymptotically Bardeen-AdS black hole via GB statistics. The analogy between the thermodynamics of the asymptotically flat Bardeen black hole from Rényi statistics and the Bardeen-AdS black hole from GB statistics makes us to consider what is the relation between the nonextensive parameter $$\lambda $$
λ
and the cosmological constant $$\Lambda $$
Λ
.
Cosmological evolution in bimetric gravity: observational constraints and LSS signatures
Authors: Bassi Ajay , Adil Shahnawaz A. , Rajvanshi Manvendra Pratap , Sen Anjan A.
Published: June 2023

Bimetric gravity is an interesting alternative to standard GR given its potential to provide a concrete theoretical framework for a ghost-free massive gravity theory. Here we investigate a class of Bimetric gravity models for their cosmological implications. We study the background expansion as well as the growth of matter perturbations at linear and second order. We use low-redshift observations from SnIa (Pantheon+ and SH0ES), Baryon Acoustic Oscillations (BAO), the growth ($$f\sigma _{8}$$fσ8) measurements and the measurement from Megamaser Cosmology Project to constrain the Bimetric model. We find that the Bimetric models are consistent with the present data alongside the$$\Lambda $$ΛCDM model. We reconstructed the “ effective dark energy equation of state”($$\omega _{de}$$ωde) and “Skewness”($$S_{3}$$S3) parameters for the Bimetric model from the observational constraints and show that the current low-redshift data allow significant deviations in$$\omega _{de}$$ωdeand$$S_{3}$$S3parameters with respect to the$$\Lambda $$ΛCDM behaviour. We also look at the ISW effect via galaxy-temperature correlations and find that the best fit Bimetric model behaves similarly to$$\Lambda $$ΛCDM in this regard.
Revisiting the Friedberg–Lee–Sirlin soliton model
Authors: Heeck Julian , Sokhashvili Mikheil
Published: June 2023

Non-topological solitons are localized classical field configurations stabilized by a Noether charge. Friedberg, Lee, and Sirlin proposed a simple renormalizable soliton model in their seminal 1976 paper, consisting of a complex scalar field that carries the Noether charge and a real-scalar mediator. We revisit this model, point out commonalities and differences with Q-ball solitons, and provide analytic approximations to the underlying differential equations.
Online Ternary Classification of Covert Speech by Leveraging the Passive Perception of Speech
Authors: Moon Jae , Chau Tom
Published: June 2023

Brain–computer interfaces (BCIs) provide communicative alternatives to those without functional speech. Covert speech (CS)-based BCIs enable communication simply by thinking of words and thus have intuitive appeal. However, an elusive barrier to their clinical translation is the collection of voluminous examples of high-quality CS signals, as iteratively rehearsing words for long durations is mentally fatiguing. Research on CS and speech perception (SP) identifies common spatiotemporal patterns in their respective electroencephalographic (EEG) signals, pointing towards shared encoding mechanisms. The goal of this study was to investigate whether a model that leverages the signal similarities between SP and CS can differentiate speech-related EEG signals online. Ten participants completed a dyadic protocol where in each trial, they listened to a randomly selected word and then subsequently mentally rehearsed the word. In the offline sessions, eight words were presented to participants. For the subsequent online sessions, the two most distinct words (most separable in terms of their EEG signals) were chosen to form a ternary classification problem (two words and rest). The model comprised a functional mapping derived from SP and CS signals of the same speech token (features are extracted via a Riemannian approach). An average ternary online accuracy of 75.3% (60% chance level) was achieved across participants, with individual accuracies as high as 93%. Moreover, we observed that the signal-to-noise ratio (SNR) of CS signals was enhanced by perception-covert modeling according to the level of high-frequency ([Formula: see text]-band) correspondence between CS and SP. These findings may lead to less burdensome data collection for training speech BCIs, which could eventually enhance the rate at which the vocabulary can grow.
Invariant means and multipliers on convolution quantum group algebras
Authors: Esfahani Ali Ebrahimzadeh , Nemati Mehdi , Esmailvandi Reza
Published: June 2023

Let [Formula: see text] be a locally compact quantum group. Then the space [Formula: see text] of trace class operators on [Formula: see text] is a Banach algebra with the convolution induced by the right fundamental unitary of [Formula: see text]. We show that properties of [Formula: see text] such as amenability, triviality and compactness are equivalent to the existence of left or right invariant means on the convolution Banach algebra [Formula: see text]. We also investigate the relation between the existence of certain (weakly) compact right and left multipliers of [Formula: see text] and some properties of [Formula: see text].
Methods and results on conserved-charge fluctuations for the Beam Energy Scan program at RHIC
Authors: Nonaka Toshihiro , Esumi Shinichi
Published: June 2023

Understanding the phase diagram of the QCD matter is one of the ultimate goals in high-energy nuclear physics. Event-by-event fluctuations of conserved charges are believed to be sensitive to the QCD phase structures. In this paper, we will review the measurements carried out in the Beam Energy Scan program at RHIC. Our focus will be on the technical details to overcome various difficulties of the measurements. We will also discuss about the current interpretations on the results and future prospects.
Comprehensive device simulation of barium silicide solar cells with diverse ETMs and HTMs
Authors: Deng Quanrong , Cheng Chuanmeng , Chen Ziyi , Huang Zhenyao , Liao Hui , Shen Yonglong , Huang Wei
Published: June 2023

The photovoltaic performances of n-i-p or inverted p-i-n BaSi2 homojunction solar cells are limited by the parasitic high light absorption of n-BaSi2 or p-BaSi2 window layer. In this work, diverse electron transport materials (ETMs) and hole transport materials (HTMs) are employed instead of BaSi2 as window layers to promote the performances of BaSi2 solar cells, and the effects of different ETMs and HTMs were simulated and comprehensively studied. For n-ETM/i-BaSi2/p-BaSi2 solar cells, the solar cell with ZnO exhibits the highest efficiency of 28.21%. As increasing the thicknesses of ETM layer from 5[Formula: see text]nm to 100[Formula: see text]nm, the efficiency for n-BaSi2/i-BaSi2/p-BaSi2 solar cell decreases seriously from 24.52% to 15.99%, while the solar cells with wide band gap ETMs including SnO2, TiO2 and ZnO show neglectable change in performances. The performances n-ETM/i-BaSi2/p-BaSi2 solar cells are affected by donor like defects more than acceptor like defects in i-BaSi2. For p-HTM/i-BaSi2/n-BaSi2 solar cells, employing Cu2O, CuI, CuSCN or NiO as HTM layer produces evident valence band discrepancies at HTM/i-BaSi2 interfaces. Heavy doping in HTM layer is necessary desired to overcome the energy band barriers. As increasing the thicknesses of HTM layer from 5 nm to 100 nm, the efficiency for p-BaSi2/i-BaSi2/n-BaSi2 solar cell also decreases from 24.52% to 15.99%, while the solar cells with wide band gap HTMs including CuI, CuSCN and NiO show neglectable change, and the efficiency for p-Cu2O/i-BaSi2/n-BaSi2 solar cells decreases slightly from 25.86% to 24.88%. The performances of p-HTM/i-BaSi2/n-BaSi2 solar cells are affected by acceptor like defects more than donor like defects in i-BaSi2.
An Improved GPS/INS Integration Based on EKF and AI During GPS Outages
Authors: Ebrahimi A. , Nezhadshahbodaghi M. , Mosavi M. R. , Ayatollahi A.
Published: June 2023

Inertial navigation system (INS) is often integrated with satellite navigation systems to achieve the required precision at high-speed applications. In global navigation system (GPS)/INS integration systems, GPS outages are unavoidable and a severe challenge. Moreover, because of the usage of low-cost microelectromechanical sensors (MEMS) with noisy outputs, the INS will get diverged during GPS outages, and that is why navigation precision severely decreases in commercial applications. In this paper, we improve GPS/INS integration system during GPS outages using extended Kalman filter (EKF) and artificial intelligence (AI) together. In this integration algorithm, the AI receives the angular rates and specific forces from the inertial measurement unit (IMU) and velocity from the INS at [Formula: see text] and [Formula: see text]. Therefore, the AI has positioning and timing data of the INS. While the GPS signals are available, the output of the AI is compared with the GPS increment; so that the AI is trained. During GPS outages, the AI will practically play the GPS role. Thus, it can prevent the divergence of the GPS/INS integration system in GPS-denied environments. Furthermore, we utilize neural networks (NNs) as an AI module in five different types: multi-layer perceptron (MLP) NN, radial basis function (RBF) NN, wavelet NN, support vector regression (SVR) and adaptive neuro-fuzzy inference system (ANFIS). To evaluate the proposed approach, we utilize a real dataset that has been gathered by a mini-airplane. The results demonstrate that the proposed approach outperforms the INS and GPS/INS integration systems with the EKF during GPS outages. Meanwhile, the ANFIS also reached more than 47.77% precision compared to the traditional method.
An Empirical Study on GitHub Sponsor Mechanism
Authors: Zhang Ziyuan , Yang Yiqian , He Haolan , Chen Jie
Published: June 2023

From May 2019, GitHub launched sponsor mechanism indicating that GitHub is moving towards deeper integration of open source development and economic support. It will bring more comprehensive and diversified support to the open source community. However, the number of developers profiting from the sponsor mechanism follows a long tail distribution. Our study found that only 31% of developers who started the sponsor mechanism received rewards, and 39.3% of them only received a reward of one dollar.

Our work focuses on identifying what factors affect the availability of sponsorship for developers in open source community. We start by defining 45 features to characterize the developers in four dimensions i.e. Personality, Advertisement, Repository and Behavior. The results of statistical analysis indicate that most of the proposed features differ significantly between the ones who received rewards (short for MTs_Yes) from those that are not. After that, we build machine learning model based on the proposed features to predict MTs_Yes. Compared with the existing work, results show that our method outperforms baselines by 30% for AUC (Area Under the Curve). In addition, we investigated the relative contribution of features in detecting MTs_Yes and analyzed the important features by using an interpretable model SHAP. Finally, based on the experimental results, we put forward corresponding and practical suggestions for developers who want to receive rewards so as to make the community of open source projects develop more harmonious.
NISe: Non-Invasive Secure Framework for Multi-Access Edge Computing
Authors: Wang Xuguo , Chen Ligeng , Liang Yu , Huang Hao
Published: June 2023

To address the emerging security challenges in Multi-Access Edge Computing (MEC), it is imperative that solutions go beyond the current infrastructure-centric measures. These methods, including authentication and access control, are insufficient to combat malware that conceals itself within ME applications. The acknowledged flaws in the ME application layer necessitate an immediate call for creative solutions. In this work, we propose a non-invasive security architecture for MEC, meticulously designed to strike a balance between performance burden and security protection capabilities. The objective of the design contains three major aspects, i.e. user experience, service density and serviceability. We conduct a thorough evaluation that enables us to quantify the significance of high bandwidth, low user experience latency and MEC serviceability. The experimental results and ablation studies indicate that our proposed method effectively balances user experience and security capabilities. This not only provides a practical and cost-effective solution but also establishes a strong precedent for the community to develop a secure MEC with superior performance in real-world production environments.
ℵ0-Distributive modules and rings
Authors: Tuganbaev Askar
Published: June 2023

Let A be a ring with minimum condition on principal right ideals. It is proved that countably distributive right (left) A-modules coincide with Artinian (Noetherian) right (left) A-modules. Rings, over which all right modules are [Formula: see text]-distributive coincide with rings of finite representation type. Rings, whose right modules are semidistributive, coincide with Kawada rings, over basis rings of which all right modules are completely cyclic.
Ultrafast nonlinear optics of Niobium selenide nanosheets
Authors: Zhou Li , Wang Yiduo , Wang Yingwei , Kang Jianlong , Zheng Wanxin , He Jun
Published: June 2023

In this work, the nonlinear optical response and the ultrafast carrier dynamics in the visible region of NbSe2 are investigated. The transient absorption (TA) spectra reveal the relaxation process, including electron–phonon scattering and phonon–phonon scattering. These results contribute to an in-depth understanding of the light-matter interactions and carrier dynamics in NbSe2 and will establish a foundation for its applications in nonlinear photonic and optoelectronic devices.
When are Baer modules extending?
Authors: Ebrahim Fatma Azmy F. , Rizvi Syed Tariq , Roman Cosmin S.
Published: June 2023

The well-known notion of an extending module is closely linked to that of a Baer module. A right [Formula: see text]-module [Formula: see text] is called extending if every submodule of [Formula: see text] is essential in a direct summand. On the other hand, a right [Formula: see text]-module [Formula: see text] is called Baer if for all [Formula: see text], [Formula: see text] where [Formula: see text]. In 2004, Rizvi and Roman generalized a result of [A. W. Chatters and S. M. Khuri, Endomorphism rings of modules over nonsingular CS rings, J. London Math. Soc.  21(2) (1980) 434–444.] in terms of modules and showed the connections between Baer and extending modules via the result: “a module[Formula: see text] is[Formula: see text]-nonsingular extending if and only if[Formula: see text] is[Formula: see text]-cononsingular Baer”. [Formula: see text] is called [Formula: see text]-nonsingular if [Formula: see text] such that [Formula: see text], [Formula: see text]. Moreover, [Formula: see text] is called [Formula: see text]-cononsingular if for any [Formula: see text] with [Formula: see text] for all [Formula: see text], implies [Formula: see text]. In view of this result, every Baer module which happens to be [Formula: see text]-cononsingular will automatically become an extending module. In this paper, our main focus is the study of [Formula: see text]-cononsingularity of modules. Our investigations are also motivated by the fact that very little is known about the notion of [Formula: see text]-cononsingularity while sufficient knowledge exists about the other three remaining notions in the preceding result. Moreover, we introduce the notion of special extending (or sp-extending, for short) of a module and show that the class of [Formula: see text]-cononsingular modules properly contains the class of extending modules and the class of special extending modules. Among other results, we obtain a new analogous version for the Rizvi–Roman’s result which illustrates the close connections between Baer and extending modules. Examples illustrating the notions and delimiting our results are provided.
COMPARING THE MESOSCALE AND MICROSCALE MECHANICAL PROPERTIES OF RAT LUNG TISSUE USING COMPUTATIONAL MODELING
Authors: DIMBATH ELIZABETH , GEORGE STEPHANIE , BRÁS LISANDRA DE CASTRO , VADATI ALEX
Published: June 2023

Current literature reports a wide range of stiffness values and constitutive models for lung tissue across different spatial scales. Comparing the reported lung tissue stiffness values across different spatial scales may provide insights into how well those mechanical properties and the proposed constitutive models represent lung tissue’s mechanical behavior. Thus, this study applies in silico modeling to compare and potentially bridge the differences reported in lung tissue mechanical properties at different length scales. Specifically, we predicted the mesoscale mechanical behavior of rat lung tissue based on in situ and in vitro microscale test data using finite element (FE) analysis and compared those computational predictions to the reported data using mesoscale uniaxial experiments. Our simulations showed that microscale-based stiffness values differed from the mesoscale data in the simulated strain range of 0–60%, with the atomic force microscopy (AFM)-based data overestimating the mesoscale data above 15% strain. This research demonstrates that computational modeling can be used as an informative and guiding tool to investigate and potentially bridge the differences in reported lung tissue material properties across length scales.
Optical Emission Spectroscopy Characterization of Nanosecond Pulsed Laser Ablation of ZnCd Plasma Plume
Authors: Muhammed Emad J. , Abbas Ahmed K.
Published: June 2023

This work used spectroscopic plasma emission analysis to investigate the parameters of Zn–Cd plasma formed in the atmosphere by a Q-switched Nd:YAG nanosecond laser system emitting infrared (1064[Formula: see text]nm) laser light with an energy output spanning 200[Formula: see text]mJ to 500[Formula: see text]mJ. The spectrometer was used to examine and record the emission spectrum profiles of (ZnCd), which helped to extract crucial plasma characteristics (i.e., [Formula: see text] and [Formula: see text]. The electron density was measured using the Stark broadening, and the plasma temperature was calculated using the Boltzmann plot technique. The electron temperature was between 1.02[Formula: see text]eV and 1.39[Formula: see text]eV, and the electron density was between (39.05 and 50.66) [Formula: see text][Formula: see text]cm[Formula: see text]. The Debye length (l), the number of particles in the Debye sphere ([Formula: see text] and the plasma frequency ([Formula: see text] can all be estimated from the electron temperature ([Formula: see text] and the electron density ([Formula: see text] ([Formula: see text]. Results indicate that plasma parameters are proportional to the energy of laser due to the increase in the intensity of spectral lines energy, and that plasma shielding of ZnCd increases with laser energy in the range of (1.20–1.23).
Assessment of the Acceptance of Internet of Things Technology in the Health Field Using TAM2: A Survey Study of Medical Staff in Nineveh Governorate
Authors: Salah Sara , Alyouzbaky Bassam A.
Published: June 2023

This study aims to identify the acceptance of Internet of Things (IoT) technologies, by medical care providers, in healthcare institutions in Nineveh Governorate. The study uses the deductive approach through the Technology Acceptance Model (TAM2). The survey was conducted using an electronic questionnaire prepared based on several studies in this field. The data population included physicians, dentists, and pharmacists with the sample size being 341. Structural equation modeling was used to test the hypotheses of the study. The results revealed that job relevance and result demonstrability have a significant impact on the perceived usefulness of using IoT technology in the medical field, whereas, job relevance, output quality, perceived ease of use, and subjective norms have no direct impact on the perceived usefulness of this technology. Furthermore, the participant-perceived benefit does not significantly influence behavioral intent.
Investigating the effect of three different types of diffusion on the stability of a Leslie–Gower type predator–prey system
Authors: Chen Hongyu , Zhang Chunrui
Published: June 2023

In this paper, we consider a Leslie–Gower type reaction–diffusion predator–prey system with an increasing functional response. We mainly study the effect of three different types of diffusion on the stability of this system. The main results are as follows: (1) in the absence of prey diffusion, diffusion-driven instability can occur; (2) in the absence of predator diffusion, diffusion-driven instability does not occur and the non-constant stationary solution exists and is unstable; (3) in the presence of both prey diffusion and predator diffusion, the system can occur diffusion-driven instability and Turing patterns. At the same time, we also get the existence conditions of the Hopf bifurcation and the Turing–Hopf bifurcation, along with the normal form for the Turing–Hopf bifurcation. In addition, we conduct numerical simulations for all three cases to support the results of our theoretical analysis.
Application of neural-network hybrid models in estimating the infection functions of nonlinear epidemic models
Authors: Li Chentong , Zhou Changsheng , Liu Junmin , Rong Yao
Published: June 2023

Hybrid neural network models are effective in analyzing time-series data by combining the strengths of neural networks and differential equation models. Although most studies have focused on linear hybrid models, few have examined nonlinear problems. This work explores the potential of a hybrid nonlinear epidemic neural network in predicting the correct infection function of an epidemic model. We design a novel loss function by combining bifurcation theory and mean-squared error loss to ensure the trainability of the hybrid model. Additionally, we identify unique existence conditions that support ordinary differential equations for estimating the correct infection function. Moreover, numerical experiments using the Runge–Kutta method confirm our proposed model’s soundness both on our synthetic data and the real COVID-19 data.
Strong zero-divisor graph of rings with involution
Authors: Kumbhar Nana , Khairnar Anil , Waphare B. N.
Published: June 2023

We associate a simple undirected graph to a ∗-ring [Formula: see text] whose vertex set is [Formula: see text][Formula: see text][Formula: see text] and two distinct vertices [Formula: see text] and [Formula: see text] are adjacent if and only if [Formula: see text]. This graph is called the strong zero-divisor graph of a ∗-ring [Formula: see text] and denoted by [Formula: see text]. In general [Formula: see text] is not connected. It is proved that [Formula: see text] is connected and [Formula: see text], when [Formula: see text] is a principally quasi-Baer (p.q.-Baer) ∗-ring. We characterize the [Formula: see text] using the lattice of central projections of a p.q.-Baer ∗-ring [Formula: see text]. We proved a sort of Beck’s conjecture for the strong zero-divisor graph [Formula: see text] of a p.q.-Baer ∗-ring [Formula: see text]. It is proved that for a p.q.-Baer ∗-ring [Formula: see text], [Formula: see text] is uniquely complemented.
Great enhancement in power conversion efficiency of DSSCs with Ni0.85Se nanoparticles as counter electrode in contrast to matrix nickel particles
Authors: Li Li , Li Guang
Published: June 2023

Pure nickel nanoparticles with diameter around 100 nm were prepared with a moderate hydrothermal method. The matrix was then selenized into Ni[Formula: see text]Se particles in a Se vapor without any damage to their original morphologies. The as-prepared N[Formula: see text]Se and Ni nanoparticles were then used as counter electrodes (CEs) in dye-sensitized solar cells. It was found that the performance of the cell with Ni[Formula: see text]Se as counter electrode is enhanced by nearly two times in contrast to the one with Ni as CEs. This provides a new method to fabricate optional counter electrode for Pt.
The Frequency Spectrum of a Harmonically Radiating Monopole Moving along Arbitrary Trajectories with Application to Helical Orbits
Authors: Ochmann Martin
Published: June 2023

The sound field of a harmonically radiating monopole moving along arbitrary trajectories in three-dimensional space is studied in the frequency range and represented as a convolution integral in Cartesian coordinates. The observation time of the motion of the source can be finite or infinite. This convolution integral is referred to as the “Cartesian Convolution Integral ” and is applied to point sources moving on special orbits described by circular and conical helices. For such helical orbits, an alternative approach in cylindrical or spherical coordinates leads to closed form expressions in the form of infinite series for the frequency spectra. The comparison of the results of the Cartesian Convolution Integral with those of the series expansion shows a very good agreement. Finally, the Cartesian Convolution Integral is used to calculate the spectral sound field of a source moving along an elliptical helix.
The Impact of Fine-Scale Currents on Biogeochemical Cycles in a Changing Ocean
Authors: Lévy Marina , Couespel Damien , Haëck Clément , Keerthi M.G. , Mangolte Inès , Prend Channing J.
Published: June 2023

Fine-scale currents, O(1–100 km, days–months), are actively involved in the transport and transformation of biogeochemical tracers in the ocean. However, their overall impact on large-scale biogeochemical cycling on the timescale of years remains poorly understood due to the multiscale nature of the problem. Here, we summarize these impacts and critically review current estimates. We examine how eddy fluxes and upscale connections enter into the large-scale balance of biogeochemical tracers. We show that the overall contribution of eddy fluxes to primary production and carbon export may not be as large as it is for oxygen ventilation. We highlight the importance of fine scales to low-frequency natural variability through upscale connections and show that they may also buffer the negative effects of climate change on the functioning of biogeochemical cycles. Significant interdisciplinary efforts are needed to properly account for the cross-scale effects of fine scales on biogeochemical cycles in climate projections.
Time‐Dependent Creep Damage Model of Frozen Soil with Unsteady Fractional Order under Temperature and Stress Coupling
Authors: Lv Hongmiao , Chen Lei
Published: June 2023

In order to study the creep characteristics of frozen soil under different confining pressures, triaxial creep tests of frozen soil under different temperatures are carried out and the creep deformation law of frozen soil under different confining pressures and different freezing temperatures is analyzed. In this paper, the unsteady Abel dashpot is constructed by the unsteady viscosity coefficient. On this basis, the fractional order of the viscosity dashpot is unsteady. Then, a time‐dependent creep constitutive model for frozen soil based on the unsteady fractional order is established. The model can better describe the law of accelerated creep deformation of rock. Through the Levenberg–Marquardt algorithm, the parameters of the triaxial creep model are identified to verify the correctness of the creep model. The results show that the model can describe the creep deformation of frozen soil well and overcome the shortcoming that the traditional model cannot describe the law of accelerated deformation. At the same time, the agreement between the model curve and the test curve is also much greater than that between the traditional Nishihara model curve and the test curve. This lays the foundation for the later use of the creep model to simulate the settlement and horizontal displacement of subgrade soil under long‐term loads and also provides a theoretical basis for the construction of other roadbed projects.
Research on Global Path Planning of Robot Based on Ant Colony Algorithm and Gaussian Sampling
Authors: Zhang Junhao , Hu Zhangfang , Wang Xingyuan
Published: June 2023

In response to the issue of the traditional ant colony algorithm (T‐ACO) with many iterations and slow convergence speed in robot global path planning, we propose an enhanced ant colony algorithm (S‐IACO) that incorporates Gaussian sampling. Firstly, the initial pheromone concentration contained in the raster map is preprocessed. Gaussian distribution sampling is adopted, and the sampling median value is used as the initial pheromone concentration of the raster map. Secondly, the heuristic function of the ant colony algorithm was improved. The number of ant colony iterations and the current path length were dynamically introduced into the heuristic function of the algorithm as influencing factors. Finally, this work redefined the pheromone update rule and introduced the concept of loss function by considering the influence of initialization pheromone on the results. By comparing with other improved ant colony algorithms, as well as PSO and GA algorithms, the S‐IACO algorithm proposed has fewer iterations and faster convergence speed.
A Novel Reservation and Allocation Approach of Shared Parking Slots considering the Noncritical Aisle Space
Authors: Huang Ke , Hong Shaozhi , Shi Zhiyuan , Jiang Haoran
Published: June 2023

Urban areas are experiencing a substantial increase in parking demand, which creates an imbalance due to the limited availability of parking facilities. To address this issue, effective parking management is necessary. Shared parking is an alternative solution that utilizes private plots which are vacant during the day to serve the parking needs of users engaged in nearby activities. While current parking management approaches have achieved high utilization rates for available parking slots, the use of aisle space in parking lots can alleviate oversaturated parking demands, especially during peak periods, for users with relatively short parking durations. This study aims to model the noncritical aisle space with time-space constraints in the shared parking slot allocation problem. We propose a programming model that maximizes the profit of the platform based on a reservation and allocation platform. Numerical experiments demonstrate that utilizing the aisle space can enhance the revenue and enable the platform to accommodate more requests that meet the requirements. Moreover, the presence of aisle parking slots may potentially result in slightly lower turnover rates of normal parking slots.
High‐Fat Diet Promotes Adipogenesis in Offspring Female Rats Induced by Perinatal Exposure to 4‐Nonylphenol
Authors: Zhang Hongyu , Ke Weiran , Chen Xi , Han Yu , Xiong Yan , Zhu Feng , Xiang Yang , Yan Rong , Cai Hongbo , Huang Shunmei , Ke Xiaoyu
Published: June 2023

Background. Both high‐fat diet (HFD) and 4‐nonylphenol (4‐NP) could affect fat formation in adipose tissue individually. We investigated whether HFD promote abnormal adipose tissue formation caused by early exposure to 4‐NP in life and preliminarily explore the possible mechanisms involved. Methods. The first‐generation rats were treated with HFD on postnatal day after pregnant rats exposure to 5 ug/kg/day 4‐NP. Then, the second generation rats started to only receive normal diet without 4‐NP or HFD. We analyzed organ coefficient and histopathology of fat tissues, biochemical index, and gene level involved in lipid metabolism in female offspring rats. Results. HFD and 4‐NP interaction synergistically increased birth weight, body weight, and organ coefficients of adipose tissue in offspring female rats. HFD accelerately aggravated abnormal lipid metabolism and increased the adipocyte mean areas around the uterus of the offspring female rats induced by prenatal exposure to 4‐NP. HFD also facilitate the regulation of gene expression involved lipid metabolism in offspring female rats induced by perinatal exposure to 4‐NP, even passed on to the second generation of female rats. Moreover, HFD and 4‐NP interaction synergistically declined the gene and protein expression of estrogen receptor (ER) in the adipose tissue of second‐generation female rats. Conclusion. HFD and 4‐NP synergistically regulate the expression of lipid metabolism genes in adipose tissue of F2 female rats and promote adipose tissue generation, leading to obesity in offspring rats, which is closely related to low expression of ER. Therefore, ER genes and proteins may be involved in the synergistic effect of HFD and 4‐NP.
Effects of CatSper Stimulation and Inhibition by Progesterone and NNC on Human Sperm
Authors: Maleki Setareh , Keshtgar Sara , Ebrahimi Bahareh , Matavos-Aramyan Hedie , Karbalaei Narges , Masjedi Fatemeh
Published: June 2023

Calcium ion enters the sperm through a specific calcium channel, CatSper. This voltage-sensitive channel is stimulated by intracellular alkalization and progesterone. This study is aimed at investigating the effects of CatSper inhibition or stimulation on sperm motility, viability, and sperm function regulators such as mitochondrial membrane potential (MMP), ATP, and reactive oxygen species (ROS) production. This study was performed on 30 semen samples of fertile volunteers, referred to Shiraz Fertility Center. The semen samples were diluted to

20
×

10

6

sperm/mL. The samples were divided randomly into control, solvent, progesterone (10 μM), NNC (2 μM), and NNC+progesterone groups. Sperm kinematics, viability, MMP, ATP content, and the amount of ROS production were assessed using VT-SPERM3.1, eosin staining, JC1 flow cytometry, bioluminescence, and chemiluminescence methods, respectively. Sperm viability and total and progressive motility were significantly decreased in the NNC and NNC+progesterone groups. The amplitude of lateral head displacement (ALH) and curvilinear velocity (VCL) was reduced in the NNC-containing groups. These parameters did not change in the progesterone group. ROS production by viable spermatozoa in the NNC and NNC+progesterone groups was significantly higher than the controls. MMP and ATP content did not show any significant difference with controls in none of the experimental groups. NNC inhibits the CatSper and reduces human sperm motility and viability. These harmful NNC effects were not due to their impact on MMP or ATP production but are likely because of intracellular calcium reduction and higher ROS production. Progesterone at 10 μM concentration had no significant effect and may not be a considerable stimulator for CatSper.
Untethered Nanotextured Thermopneumatic Soft Actuators Operable with Different Stimuli: Thermal Blowing, Infrared Light, and Electromagnetic Field
Authors: Kim Yong Il , Kim Si Wung , An Seongpil , Yarin Alexander L. , Yoon Sam S.
Published: June 2023

In this study, untethered nanotextured thermopneumatic soft actuators (UTPSAs) were developed using a soft elastomer body encapsulating a volatile fluid (Novec 7000), which underwent a phase change (evaporation) when stimuli that convert energy into heat were applied using wireless transmission. Herein, we analyzed three types of stimuli: (i) thermal blowing, (ii) irradiation with infrared light, and (iii) electromagnetic energy transmission. In the third case, an electromagnetic field induced an electric current in a wire coil embedded in an elastomeric body, thus providing Joule heating to induce fluid evaporation. The bending curvature and force generated during bending were examined under various operational conditions, which enable one to select the optimal operating mechanism of UTPSAs for a specific environment. Specifically, diverse operating capabilities of UTPSAs are expected to be useful in dynamic environments, e.g., rescue situations. In addition, as a potential application, a crawler-configured UTPSA was fabricated, and its operation was demonstrated.
Confirmed Malaria Cases in Children under Five Years: The Influence of Suspected Cases, Tested Cases, and Climatic Conditions
Authors: Tawiah Kassim , Asampana Asosega Killian , Ansah Richard Kwame , Appiah Sampson Takyi , Otoo Dominic , Aponye Isaac Aganeba , Tinbil Thomas , Addai Isaac Mensah
Published: June 2023

Tropical and potentially fatal malaria is brought on by the parasite Plasmodium spp which spreads through infected female anopheles mosquitoes within the human populations. In Ghana, malaria is endemic and perennial, with distinct seasonal fluctuations in the northern part. Children aged below five years are among the population most vulnerable to malaria in Ghana. This study’s goal is to establish how suspected malaria cases, tested malaria cases, and climatic conditions impact confirmed malaria cases in children under five years in the Sunyani Municipality, Bono Region, Ghana. The dependent variable, monthly number of confirmed cases of malaria in children under five years, was modelled with the independent variables, monthly number of tested cases of malaria in children under five years, mean monthly relative humidity, mean monthly rainfall, and mean monthly temperature, in the Sunyani Municipality. We employed multiple linear regression after data transformation, exploratory data analysis, and correlation analysis. Results show that tested malaria cases and climatic factors significantly influence confirmed malaria cases in children under 5 years. About 41.8% of variations in confirmed malaria cases among children under 5 years is attributed to climatic factors and the number of tested cases. Moreover, results show that increase in tested cases and rainfall leads to more confirmed malaria cases among children under 5 years, while increase in temperature reduces malaria infections. To reduce the incidence of malaria in children under five years, the government and its stakeholders should encourage parent to let their children sleep in treated mosquito nets, distil stagnant waters during raining seasons, spray bushes with antimosquito insecticides, and destroy all breeding grounds of mosquitoes at all times. We proposed that all malaria cases should be laboratory tested and properly confirmed.
Supplementary Fig. 4 from Antitumor Efficacy of the Novel KIT Inhibitor IDRX-42 (Formerly M4205) in Patient- and Cell Line–Derived Xenograft Models of Gastrointestinal Stromal Tumor (GIST)
Authors: De Sutter Luna , Wozniak Agnieszka , Verreet Jasper , Vanleeuw Ulla , De Cock Lore , Linde Nina , Drechsler Christine , Esdar Christina , Sciot Raf , Schöffski Patrick
Published: June 2023

Supplementary Fig. 4.(A) Average number of mitotic cells per treatment group in 10 high power fields assessed on phospho-histone H3 (pHH3) immunostaining and (B) percentage of proliferative cells per treatment group per 5 high-power fields assessed on Ki-67 immunostaining.
Figure S5 from Immunogenomic Landscape of Neuroendocrine Prostate Cancer
Authors: Bhinder Bhavneet , Ferguson Alison , Sigouros Michael , Uppal Manik , Elsaeed Ahmed G. , Bareja Rohan , Alnajar Hussein , Eng Kenneth Wha , Conteduca Vincenza , Sboner Andrea , Mosquera Juan Miguel , Elemento Olivier , Beltran Himisha
Published: June 2023

Suppl Figure 5. Comparative analysis between NEPC and SCLC.
Figure S2 from Immunogenomic Landscape of Neuroendocrine Prostate Cancer
Authors: Bhinder Bhavneet , Ferguson Alison , Sigouros Michael , Uppal Manik , Elsaeed Ahmed G. , Bareja Rohan , Alnajar Hussein , Eng Kenneth Wha , Conteduca Vincenza , Sboner Andrea , Mosquera Juan Miguel , Elemento Olivier , Beltran Himisha
Published: June 2023

Suppl Figure 2. T-cell signature-based classification of prostate cancer types and other independent cancer cohorts.
Figure S1 from Immunogenomic Landscape of Neuroendocrine Prostate Cancer
Authors: Bhinder Bhavneet , Ferguson Alison , Sigouros Michael , Uppal Manik , Elsaeed Ahmed G. , Bareja Rohan , Alnajar Hussein , Eng Kenneth Wha , Conteduca Vincenza , Sboner Andrea , Mosquera Juan Miguel , Elemento Olivier , Beltran Himisha
Published: June 2023

Suppl Figure 1. Classification of prostate tumors based on T-cell immune status
Supplementary Table S4 from Autocrine 17-β-Estradiol/Estrogen Receptor-α Loop Determines the Response to Immune Checkpoint Inhibitors in Non–Small Cell Lung Cancer
Authors: Anobile Dario P. , Salaroglio Iris C. , Tabbò Fabrizio , La Vecchia Sofia , Akman Muhlis , Napoli Francesca , Bungaro Maristella , Benso Federica , Aldieri Elisabetta , Bironzo Paolo , Kopecka Joanna , Passiglia Francesco , Righi Luisella , Novello Silvia , Scagliotti Giorgio V. , Riganti Chiara
Published: June 2023

Primers list for RT-PCR
Supplementary Figure S7 from Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML
Authors: Letson Christopher T. , Balasis Maria E. , Newman Hannah , Binder Moritz , Vedder Alexis , Kinose Fumi , Ball Markus , Kruer Traci , Quintana Ariel , Lasho Terra L. , Finke Christy M. , Almada Luciana L. , Grants Jennifer M. , Zhang Guolin , Fernandez-Zapico Martin E. , Gaspar-Maia Alexandre , Lancet Jeffrey , Komrokji Rami , Haura Eric , Sallman David A. , Reuther Gary W. , Karsan Aly , Rix Uwe , Patnaik Mrinal M. , Padron Eric
Published: June 2023

Supplemental Figure 7 shows clonogenicity data associated with 6A broken down by patient sample and a non-transplanted control sample stained with CD45 corresponding to Figure 6E.
Supplementary Table S1 from Autocrine 17-β-Estradiol/Estrogen Receptor-α Loop Determines the Response to Immune Checkpoint Inhibitors in Non–Small Cell Lung Cancer
Authors: Anobile Dario P. , Salaroglio Iris C. , Tabbò Fabrizio , La Vecchia Sofia , Akman Muhlis , Napoli Francesca , Bungaro Maristella , Benso Federica , Aldieri Elisabetta , Bironzo Paolo , Kopecka Joanna , Passiglia Francesco , Righi Luisella , Novello Silvia , Scagliotti Giorgio V. , Riganti Chiara
Published: June 2023

Representativeness of Study Participants
Supplementary Figure S9 from Autocrine 17-β-Estradiol/Estrogen Receptor-α Loop Determines the Response to Immune Checkpoint Inhibitors in Non–Small Cell Lung Cancer
Authors: Anobile Dario P. , Salaroglio Iris C. , Tabbò Fabrizio , La Vecchia Sofia , Akman Muhlis , Napoli Francesca , Bungaro Maristella , Benso Federica , Aldieri Elisabetta , Bironzo Paolo , Kopecka Joanna , Passiglia Francesco , Righi Luisella , Novello Silvia , Scagliotti Giorgio V. , Riganti Chiara
Published: June 2023

PD-L1 inhibition does not affect amount and phosphorylation of estrogen receptor α.
Female-derived ERα lowNCI-H1385 and ERα highNCI-H1975 cells, male-derived ERα lowA549 and ERα highNCI-H1650 cells were treated 24 h in the absence (-) or presence (+) of 1 μg/mL atezolizumab (Atezo), a PD-L1 inhibitor, then lysed and analyzed for the indicated proteins in nuclear extracts. TBP is included as control of equal protein loading. The image is representative of one of three experiments.
Supplementary Figure S1 from Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML
Authors: Letson Christopher T. , Balasis Maria E. , Newman Hannah , Binder Moritz , Vedder Alexis , Kinose Fumi , Ball Markus , Kruer Traci , Quintana Ariel , Lasho Terra L. , Finke Christy M. , Almada Luciana L. , Grants Jennifer M. , Zhang Guolin , Fernandez-Zapico Martin E. , Gaspar-Maia Alexandre , Lancet Jeffrey , Komrokji Rami , Haura Eric , Sallman David A. , Reuther Gary W. , Karsan Aly , Rix Uwe , Patnaik Mrinal M. , Padron Eric
Published: June 2023

AZD1208 Synergy Plots and BETi Resensitization Data