bluuebunny/crossref_metadata_2025 huggingface dataset:
Maternal and Neonatal Outcomes Associated with Mild COVID-19 Infection in an Obstetric Cohort in Brazil
Authors: Santos Carolina A. D. , Fonseca Filho Gentil G. , Alves Manoella M. , Macedo Erianna Y. L. , Pontes Monise G. de A. , Paula Artemis P. , Barreto Carolina T. R. , Zeneide Felipe N. , Nery Andréia F. , Freitas Reginaldo A. O. , D’Souza-Li Lília
Published: October 2022

Previous coronavirus epidemics were associated with increased maternal morbidity, mortality, and adverse obstetric outcomes. Reports for SARS-CoV-2 indicate that the obstetric population is at increased risk for severe illness, although there are still limited data on mild COVID-19 infection during pregnancy. To determine the association between mild COVID-19 infection during pregnancy, and maternal and neonatal outcomes, we performed a prospective cohort study among pregnant women with COVID-19 and a control group. Postnatal depressive symptoms were assessed using the Edinburgh Postnatal Depression Scale. We recruited 84 pregnant women with mild COVID-19 and 88 pregnant women without COVID-19. All participants were unvaccinated. The most common acute COVID-19 symptoms were headache (82.1%), loss of smell (81%), and asthenia (77.4%). The median duration of long COVID symptoms was 60 days (interquartile range, 130). Pregnant women with a COVID-19 diagnosis were at greater risk for obstetric ultrasound abnormalities—mainly, fetal growth restriction (relative risk [RR], 12.40; 95% CI, 1.66–92.5), premature birth (RR, 2.62; 95% CI, 1.07–6.43), and postpartum depression (RR, 2.28; 95% CI, 1.24–4.21). Our results alert clinicians to the consequences of COVID-19 during pregnancy, even in mild cases, given the increased risk of ultrasound abnormalities, premature birth, long COVID symptoms, and postpartum depression. National guidelines on preventive measures and treatments should be based on scientific evidence, including attention to the impact on health and family needs during and after the COVID-19 pandemic.
Investigation of the Effect of Glass Sand Used in SCC on the Behavior of the SCC Stress- Strain Relationship
Authors: ETLİ Serkan
Published: October 2022

Glass, who is found as a waste in nature, seems to be among the causes of fires in forest areas and landfills, especially with the increase in temperature in recent years. Within the scope of the study, waste soda glass bottles collected from waste sites and natural environment were separated by passing through 0.25-0.5 mm sieves after grinding. The self-compacting concrete (SCC) produced with this glass sand were replaced with the natural sand inside. Natural sand and glass sand were substituted in increments of 5% between 5% and 35% by volume. SCC were tested with fresh feature tests where it provides regulatory standards. Stress-strain relationships were obtained for 7- and 28-days old samples from the mixtures obtained. These relations were evaluated by comparing them with the concrete model, which is frequently used in the literature. It was observed that the resulting stress-strain relations converged well to the model chosen especially at the age of 7 days but diverged from the model used at the age of 28 days, especially in the initial part.
Investigation of Polylactic Acid (PLA) / Titanium Carbide (TiC) Nanocomposite Films Gamma Ray Shielding Properties
Authors: YILMAZ Mücahit
Published: October 2022

In this study, gamma rays absorption properties of Polylactic Acid (PLA)/Titanium Carbide (TiC) nanocomposite films produced by containing 5% TiC were investigated. In applications where radioactive sources such as industry and medical are used, protection from the harmful effects of radiation is very important. Researches on materials to be used in shielding as an alternative to lead are becoming widespread. Comfortable, easily shaped, thin, durable, non-toxic to the environment and the user are the features sought in an ideal shield materials. For this purpose, the gamma ray absorption properties of the PLA/TiC nanocomposite material and its effect on radiation shielding were investigated. The linear attenuation coefficient value of the sample with different thicknesses was obtained with the NaI(TI) scintillation detector. A monochromatic gamma source, Cs-137 gamma radioisotope with 661.62 keV energy was used as the gamma radiation source. To determine the gamma ray shielding ability of materials Half value layer (HVL), tenth value layer (TVL) and radiation shielding efficiency (RPE) parameters of the material were calculated.
Socio-Economic View of Fisheries Processing Sector Employees: Black Sea Region-Türkiye
Authors: ALTUN Muhammed Ali , ÇAĞLAK Emre
Published: October 2022

In this study, the socio-economic status of the employees who work in the seafood processing plants operating in the Black Sea region provinces was examined in order to reveal the social and economic data. 37 enterprises, which have a production permit from the Ministry of Agriculture and Forestry, are located in 7 provinces in the Black Sea region, where 18 provinces are located. It has been studied with 532 interviewers in 28 companies that are actively operating, with a participation of 24 questions each. 19 of the enterprises work for fish and fish products, 4 are for snails, and 5 are for fish flour and oil processing plants. 63.9% of the employees are male. When we look at the distribution of the employees’ age groups, the rate of 31-40 years was the highest with a percentage of 36.64%. Regarding the education levels, it is seen that the secondary school graduates constitute the highest rate with a percentage of 38.91%. It has been detected that 99.62% of the employees have social security, and all of them take advantage of the social security institution. For the marital status, it is determined that 73.50% of the employees are married.
Examining Traditional Winter Preparations: The Case of Bitlis Cuisine
Authors: ŞİMŞEK Aykut , ÇELİK YEŞİL Seher
Published: October 2022

Today, the term that corresponds to winter preparation is to ensure that the products produced in the season take place in human nutrition for a longer period of time due to their biological and physical structures. It is also a method of preservation. Considering the 81 provinces of Turkey's geography, it is thought that each region has its own winter preparations. This study aims to examine the winter preparations of Bitlis cuisine. In this direction, interviews were conducted with 13 female participants between 20-25 December 2021 using the semi-structured interview technique. As a result of the interviews, it was determined that the winter preparations were for drying, fermentation, and meat products. Among them, it has been determined that there are products such as sauerkraut called çörti, salted cabbage brine called şör leaf, dried meat, dried head and leg and dried fish, basma cheese, which is kept in the soil and kept for five or six months to mellow. In addition, fruits and vegetables obtained from the temperate districts of the region are dried and stored.
Digital Transformation and Strategic Analysis of Human Resource Value
Authors: Liu Li-Lun , Su Yao-Jen
Published: October 2022

Abstract

With the development of COVID-19, the corporate value evaluation model has gradually changed from traditional concepts to the digital information. This article aims to analyse how the value chain of human resource management practice creates competitive advantages and value for enterprises, focuses on the value chain model, and explores value activities in practice. The decision-making model and research topic direction of human resource management are put forward to provide a reference for personnel management. Combining AMO (ability, motivation, and opportunity), employee competence, employee motivation, employee opportunity, and to use the following formula to maximize the organization’s revenue. Digital transformation has improved the quality of human resource management. This study is based on the implementation of human resource management systems and human resources in listed companies in Taiwan. The survey results show that capital, employee engagement, organizational behaviour, and digital transformation help practitioners understanding.

JEL classification numbers: M1, M12.
Keywords: Enterprise Value, Competitive Advantage, Organizational Performance, Digital Transformation.
Study on usage of Land and changes in Ecology in Babile Elephant Sanctuary, Eastern Ethiopia
Authors: Geleta Taye Lemma , Mengesha Girma , Workeneh Sintayehu
Published: October 2022

The focus of this paper is to investigate how the land covers in Eastern Ethiopia's Babile Elephant Sanctuary (BES). The spatiotemporal patterns of land-cover changes involved using remote sensing, geographic information systems, and questionnaires. Researchers used the Landsat images acquired in 1972, 2000, and 2021 were used. The result revealed that bushland and agricultural land areas expanded highest over the study period (1972–2021) at the expense of natural forests. With an average annual loss rate of 8343.12 ha, riverine forests and woods lost a substantial amount of land cover. The woodland and riverine forest cover decreased steadily from 59.85 and 20.56% in 1972 to 30.37 and 3.13% in 2021.From 1972, the coverage of bushland, agricultural land, bare land, and settlement increased to 17.57, 1.75, 0.23, and 0.04%, respectively, to the year 2021, when it occupied 34.68, 22.30, 4.95, and 4.57%, respectively, of the total land area. Several bushland areas in the sanctuary while data collected for this study, with likely impacts were observed (such as tree-cutting) on the forest and riverine habitat. As a result, there was currently a greater area covered by wilderness patches (i.e., 34.68 % in 2021). The result showed that the increasing agricultural land and settlements become a threat to the ecological integrity of elephant habitats, leading to habitat fragmentation and human encroachment on elephant habitats, and high pressure and competition over resources. Based on the study, the interpretation drawn is that, BES is necessary to build gaps in knowledge for conservationists to design plans for the restoration of habitats and the species by lowering the impact on land cover change, immediate action, and restoring mechanisms to conserve biodiversity and associated ecosystem services in the area.
Electoral Violence in Nigerian Polity: Causes and Consequences
Authors: PALLY AGIDI EJIME
Published: October 2022

Nigerian polity over the years has witnessed several electoral processes and elections which have been characterized by various forms of violence. These have equally resulted into negative indices such as political apathy among the electorates, loss of lives and properties, low economic growth, poor standard of living and stunted political development. The paper examines electoral violence and its prevalence in Nigerian polity. The paper focuses on the factors behind the continuous occurrences of electoral violence in almost all the elections conducted in Nigeria at the federal, state and local government levels since independence. The study is a qualitative research which relied on secondary sources of information and anchored on elite theory as its theoretical framework of analysis. The paper finds that poverty, unemployment, financial inducement of elective positions, bad governance and loose security architecture among others are the causes of electoral violence in Nigeria. The paper further reveals that electoral violence creates fear among the electorates and some interested candidates which hinders their political participation and interests resulting in political apathy. The paper posits that electoral violence is an obstacle to good governance, peaceful coexistence and political development in Nigeria. The paper therefore recommends among others, that political education, public enlightenment, eradication of poverty through people oriented government policies and creation of jobs for the idle youths will help to ameliorate the occurrences of electoral violence in Nigeria polity.
Study ofSocial Behavior of Village Consultative Body Members (BPD)in Tunjungtirto Village, Singosari Sub-District, Malang Regency
Authors: Suardika Ida Bagus , Weni I Made , Widjajan Roos
Published: October 2022

This study aims to describe and analyze the social behavior of BPD members in Tunjungtirto Village, Singosari Sub-District, Malang Regency, with indicators namely attitudes, actions, and decision making and describe and analyze internal and external causes behind the social behavior of BPD members in Tunjungtirto Village. This study uses a qualitative approach. The technique goes through three stages of this research, namely: data condensation, data display, and drawing conclusions/verification. The results of the analysis show that the members of the BPD of Tunjungtirto Village will basically support the decisions of the village government if the decisions are carried out in accordance with the main tasks and results of the village deliberations. When members of the Tunjungtirto Village BPD feel disapproval of the village government's decision, then the actions taken are (1) remain silent and do not express an opinion, (2) continue to sign the minutes which means agreeing to the results of the deliberation decision, even though this action is against their conscience. (3) showing disapproval through passive aggression, for example not attending meetings and displaying displeased expressions through facial expressions or voice intonation, and (4) refusing to sign the minutes even though BPD members understand that if only one person does not sign, then the result of the deliberation decision will continue to run. The members of BPD Desa Tunjungtirto decided to keep signing the minutes, which meant agreeing to the decision of the deliberation. The decision taken is actually contrary to their attitude. Religious values, cultural values, and personal values are internal factors that influence the social behavior of BPD members in Tunjungtirto Village. The existence of a control function from community members, imitating the behavior of previous members of the Tunjungtirto Village BPD, and the ewuh pakewuh culture which is very attached to become external factors that affect the social behavior of Tunjungtirto Village BPD members.The social behavior of BPD members of Tunjungtirto Village is motivated by internal factors and external factors that result in discrepancies between their attitudes and actions, resulting in cognitive dissonanc.
A Study of the Omnibus Law Method in Law Establishment in Indonesia
Authors: Gainau Keny , Supriyadi  , Susanto
Published: October 2022

Simplifying complex regulations to encourage investment and employment has made the Omnibus Law method in the Job Creation Act, which was initially believed to accommodate investment and employment, have a very noble purpose. However, the Formation of the Law must adhere to the formation procedures outlined in law number 12 of 2011 regarding the Formation of laws and regulations. In reality, law number 11 of 2020 about employment creation, an example of the omnibus legislative technique, is not in conformity with the formation procedure envisioned by law number 12 of 2011. The method of research is normative legal research with a statute-based approach. The primary concerns of this study are whether the omnibus law approach is consistent with the Indonesian legal system and whether it is suitable for use in the formulation of laws in Indonesia based on law number 12 of 2011. To evaluate and analyze the use of the omnibus law method in the Indonesian legal system, as well as the compatibility of Law No. 11 of 2020 about job creation as a type of the omnibus law method with the principle of establishing Legislation based on Law No. 12 of 2011.
Suicide Reporting: An Analysis of Selected Nigerian Online News Sites (September2018-August2020)
Authors: Onakoya Toluwanimi , Aririguzoh Stella
Published: October 2022

In 2019, the World Health Organisation released a report which revealed that Nigeria had the highest suicide rate in Africa. Employing a mixed-method approach, the researcher examined suicide reportage in Nigeria, between 2018-2020, comparing it to the standards set by the World Health Organisation’s suicide reporting guidelines. A total of 227 articles and 3 editors were examined and interviewed. The findings revealed that although the editors stated that they were aware of and followed such guidelines, suicide incidents were reported irresponsibly. The research’s result indicates that journalists need to be re-oriented on suicide and reporting best practices.
Operational Schedules for Heavy Equipment Transportation Vehicles: A Case Study of Sangatta City of Indonesia(Study of Policy on Regulation of HETV Operational Hours)
Authors: Farisaputra Alpha Wahyu , Prianto Budhy , Jatmikowati Sri Hartini
Published: October 2022

The purpose of this research is to describe and analyze the Implementation of the Policy on Regulation of Operational Hours for Heavy Equipment Transport Vehicles(HETV’s) in Sangatta City based on the Regulation of the Regent of East Kutai Number 20 Years, and to describe and analyze the factors supporting and inhibiting the Implementation of Policy on Regulation of Operational Hours for Heavy Equipment Transport Vehicles in Sangatta City based on the Regulation of the Regent of East Kutai Number 20 Years. This type of descriptive research uses a qualitative methodology. By using the theory of public policy implementation, this study aims to describe and analyze the implementation of the policy on Regulation of Operational Hours of Heavy Equipment Transport in Sangatta City, based on the Regulation of the Regent of East Kutai Number 20 of 2018. The findings of this study are that the implementation of the policy on Regulation of Operational Hours of Transport Vehicles Heavy Equipment in Sangatta City is based on East Kutai Regent Regulation Number 20 of 2018 in terms of mechanisms, coordination, prohibition of crossings, and violations that occur not continuously, clear and consistent communication; additional sources of authority owned by the executor, selective appointment of the executor.
Lokaal gebruik van dehydro-epiandrosteron voor de behandeling van vaginale atrofie na borstkanker
Authors: Vandamme S. , Willers N. , Han S.
Published: October 2022

Vaginal dehydroepiandrosterone for the treatment of vaginal atrophy in breast cancer survivors

Vaginal atrophy is a common problem in breast cancer survivors, but often remains undiscussed with the health care professional. Vaginal oestrogens are the standard treatment, yet this treatment remains quite controversial in breast cancer survivors.

Vaginal dehydroepiandrosterone (DHEA) appears to be a promising alternative. PubMed was screened for clinical trials on offering local DHEA for the treatment of vaginal atrophy in breast cancer survivors.

Only 2 published articles, both covering 1 randomized double-blind controlled trial, were found. In that study, 443 participants were equally randomized into 3 arms: each participant receiving daily vaginal administration during 12 weeks of 3.25 mg DHEA, 6.5 mg DHEA and a plain moisturizer.

All arms showed improvement in both vaginal dryness and dyspareunia, yet no dose of DHEA administration led to a statistically significant difference on both parameters compared to the plain moisturizer. Some significant self-reported side effects were observed. Serum DHEA sulphate and testosterone increased significantly depending on the DHEA dose in comparison to a plain moisturizer, yet still remaining within the normal postmenopausal range. Oestradiol amounts also increased in the 6.5 mg DHEA group, but not in the 3.25 mg DHEA group and, remarkably, not in women taking an aromatase inhibitor.

Vaginal DHEA improves the symptoms of vaginal atrophy, especially in terms of sexual experience. However, further research is needed on the efficacy and safety of long-term use of vaginal DHEA in breast cancer survivors, especially in case of hormone-sensitive breast cancer.
“The use of the page as an artistic medium”: Catalina Parra and her work in editorial publications in the 1970s.
Authors: Izquierdo Valentina
Published: October 2022

In this article I explore the participation of Chilean artist Catalina Parra as a visualizer and diagrammer in certain editorial publications (Manuscritos Magazine and some books and catalogues of V.I.S.U.A.L.). These works offer a key to the analysis of the different production techniques of the artist, being fundamental montage techniques and theories form the basis of this exploration as it is through her work that words and images are manipulated as compositional material on the pages/media to be reviewed and in her photomontages. And it is in this common exercise where effects could be recognised that allow us to problematise certain states of art, as well as aesthetic and intellectual questions.
Managing COVID- 19 Crisis in Nigeria: Impact on Informal Small and Medium Scale Enterprises in Anambra State
Authors: Madueke Chinwe Monica , Chukwuka Stephen Maduabuchukwu , Ozoh Joan Nwamaka , Akolisa Chidiogo Jane , Imoagwu Chika Priscilla
Published: October 2022

The outbreak of COVID-19 Pandemic disrupted the Nigerian economy and brought the global economy to a standstill. The crisis led to a drop in production volumes and severe market circumstances as the epidemic continued to wreak havoc on the country, SMEs in the informal sector are battling to survive. This study examines the effect of COVID-19 government palliative on informal Small and medium enterprises (SMEs) in Anambra State, Nigeria. The researcher used purposive sampling technique and selected all informal enterprises in public places using questionnaire as an instrument for data collection which were distributed to 200 SMEs owners in Anambra State. Three commercial areas were selected namely Awka, Onitsha and Nnewi, 180 out of 200 questionnaires were viable. From the Research conducted, COVID-19 Pandemic was found to have a negative impact on volume of sales, revenue, and non-payment of wage during the Crisis. The finding also showed that most SMEs did not receive government palliative which would have help them in boosting the SMEs during the Pandemic, this make most of them to shutdown their business. Lastly, SMEs adopted some strategies like cutting the salaries of their staff during Covid 19 and laying off of workers (with no plan to recall them), and ensuring business continuity. This research recommends that government should support SMEs in informal sector in meeting their operational expenses as this will assist them in reviving and boosting their business which will help them increase their income as well as recoup revenue lost during the pandemic.
USO DO DASHBOARD NA GESTÃO DE INDICADORES, UMA AVALIAÇÃO DA IMPLANTAÇÃO AOS IMPACTOS NA GOVERNANÇA DA ATENÇÃO DOMICILIAR: PROTOCOLO DE REVISÃO DE ESCOPO
Authors: Saldanha de Menezes Fortes Artemisa , Cavalcante Ramalho Brilhante Ana Paula
Published: October 2022

Objetivo: o presente trabalho tem por objetivo elaborar um protocolo de revisão de escopo, que visa compreender os conteúdos, benefícios, aplicabilidade e fases de avaliação para implantação do Dashboard de governança da atenção domiciliar. Método de Revisão: A metodologia da pesquisa terá como base os estudos da prática baseada em evidencias (PBE) e os princípios do protocolo de revisão de escopo através de suas fases de construção, conforme orientação do Manual da JBI (Joanna Briggs Institute) e utilizar-se-á como critério de inclusão na amostra, artigos nacionais e internacionais que respondam a estratégia de busca embasada nos critérios P(população) = Governança da Atenção Domiciliar, C(conceito) = Tecnologia Digital Dashboard e C(contexto) = Gestão de Indicadores, sendo elegíveis artigos que estejam completos e disponíveis gratuitamente nas bases de dados Lilacs via BVS, PUBMED, SciELO, SCOPUS e fonte de Literatura Cinzenta – Google Acadêmico. Os dados passarão pelo crivo de dois revisores que no caso de divergência na análise, contarão com um terceiro. Apresentação e Interpretação dos resultados: Os resultados serão apresentados tendo como base estrutural de análise a proposta por Bardin, por meio de tabelas, fluxos, gráficos, análises percentuais e comparativos que explicitarão as informações extraídas, além de dispor de discussão crítica embasada nos achados e na verificação realizada pelos revisores.
Aplicação de escalas de teoria de resposta ao item na área de tecnologia da informação e comunicação
Authors: Borba Eduardo Henrique de , Tezza Rafael
Published: October 2022

RESUMO
Tecnologias da Informação e Comunicação (TICs) são ferramentas essenciais no cotidiano atual, incluindo Educação a Distância (EaD), comércio eletrônico etc. Para captar a percepção de seus usuários, a Teoria de Resposta ao Item (TRI) se revela como um instrumento robusto e eficaz. Sendo assim, este artigo tem como objetivo explorar a aplicação de escalas da TRI no contexto de TICs, focando na avaliação das escalas utilizadas nas pesquisas. Para isso, foi desenvolvida uma busca sistemática nas bases de dados da EBSCO, SCOPUS e Web of Science. Foram encontrados 16 artigos que aplicam a TRI em situações de TICs, estes aplicaram o Modelo de Resposta Gradual, o Modelo Logístico de Um, Dois e Três Parâmetros, Modelo de Desdobramento Graduado Unidimensional e Modelos Multidimensionais. Foram evidenciadas escassez de aplicação da TRI em conjunturas tecnológicas, apesar da sua robustez e variabilidade de modelos; e carência de destaque à elementos iniciais do desenvolvimento de uma escala precisa e coerente.
Palavras-chave: TICS; TRI; escala; confiança; validade.
Fracture Pressure Calculation Method in Transversely Isotropic Formation by Logging
Authors: GUI Junchuan , XIA Hongquan , SANG Yu , ZENG Bo , WU Jian , SONG Yi , HUANG Haoyong , XU Ersi
Published: October 2022

Fracture pressure is one of the key parameters in drilling engineering,completion engineering and hydraulic fracturing technology.Using logging data to calculate continuous formation fracture pressure is the most commonly used method,but the effect of formation anisotropy is usually ignored by the conventional method.To this end,the formation is considered as the transversely isotropic medium,and the Young􀆳s modulus and Poisson􀆳s ratio in the vertical and horizontal directions are obtained by calculating the elastic stiffness matrix.By considering the relationship between vertical stress and horizontal strain,a novel formula is derived to calculate the formation fracture pressure based on the relationship between depth and strain.Finally,this novel formation fracture pressure formula is optimally programmed and applied to the calculation of the formation fracture pressure in Block L.The comparison between the field measurement results of formation fracture pressure and the logging prediction results shows that the measured formation fracture pressure of hydraulic fracturing at 4,266m in Well L1 is 90.5MPa,while the fracture pressure calculated by the traditional method is 93.5MPa (with a relative error of 5.4% compared with the measured results),and the fracture pressure calculated by the transversely isotropic method is 95.4MPa (with a relative error of 3.3% compared with the measured results).The accuracy of the formation fracture pressure calculated by the new method is better than that of the formation fracture pressure calculated by the traditional method,which is applicable and comparable.
Coinfection by Group C Streptococcus dysgalactiae subsp. equisimilis and Flavobacterium davisii in Nile Tilapia from the United States
Authors: Shoemaker C.A. , Heckman T.I. , Soto E. , LaFrentz B.R. , Beck B.H. , Paulson M. , García J.C.
Published: October 2022

Streptococcal disease and columnaris disease are common in tilapia aquaculture across the globe. Coinfections are also common but often overlooked or not reported. In the present study, we describe the clinical presentation of streptococcosis and columnaris coinfection in diseased Nile tilapia (Oreochromis niloticus), and the phenotypic (Lancefield grouping, hemolytic pattern, biochemical characteristics, antibiotic susceptibility) and genotypic (multilocus sequence analysis for streptococci and multiplex PCR for flavobacteria) characterisation of its etiological agents, namely Group C Streptococcus dysgalactiae subsp. equisimilis and Flavobacterium davisii. We further fulfilled Koch’s postulates with the S. dysgalactiae subsp. equisimilis isolate in genetically improved Nile tilapia.
Coop kämpft gegen steigende Preise
Authors: Hofmann Janine
Published: October 2022

In der Schweiz spitzen sich die Preiskonflikte zwischen Handel und Industrie trotz geringerer Inflation zu. Die Coop-Gruppe investiert in die Preise und listet Mars-Artikel aus.
Milch ist in Frankreich viel günstiger als in Deutschland
Authors: Murmann Christoph
Published: October 2022

In ganz Europa erreichen die Erzeugerpreise für Milch Rekordniveau, nur in Frankreich liegen sie weit darunter. Der französische Handel verweigert stärkere Preiserhöhungen. Für deutsche Verarbeiter ist das ein Problem.
Arla will das Markengeschäft stärken
Authors: Rück Daniela
Published: October 2022

Der Molkerei-Riese Arla lanciert eine breit angelegte Marketingkampagne, die die gleichnamige Dachmarke in den Fokus rücken beziehungsweise die Nachhaltigkeitsaktivitäten des Unternehmens betonen soll.
TOP 50-LEH Europa (Prognose 2022)
Authors: Biehl Bernd
Published: October 2022

Die Schwarz-Gruppe vergrößert 2022 ihren Vorsprung als größter europäischer Lebensmittelhändler. Ein großes Mittelfeld an vorwiegend nationalen Anbietern sichert den Wettbewerb in der Breite.
Personalmangel belastet den Verkauf
Authors: Kapell Elisabeth
Published: October 2022

Verkaufsmitarbeiter fühlen sich aktuell besonders belastet, doch Gesundheitsförderung ist ein Stiefkind der Personalchefs. Dabei kann ein gut gemachtes Präventionsprogramm als Pluspunkt auch bei der Rekrutierung helfen.
Quick-Commerce-Anbieter stoßen ins Kuriergeschäft vor
Authors: Manner-Romberg Horst
Published: October 2022

Kapitalanleger sind offenbar nach wie vor bereit, umfangreiche Mittel in Essens- und Lebensmittel-Lieferdienste zu investieren. Gleichzeitig verlangen sie schwarze Zahlen. Die Quick-Commerce-Firmen drängen deshalb zunehmend in den Bereich der klassischen City-Kurierdienste.
Smart-Box erweist sich als tauglich und nachhaltig
Authors: Haubenreißer Matthias
Published: October 2022

Die neue Mehrweg-Transportkiste „Smart-Box“ kann im Piloteinsatz überzeugen. Die Logistikkosten lassen sich dank der Boxen um bis zu 20 Prozent senken, zeigt der erste Einsatz in der Praxis.
Simulationssoftware identifiziert Schwachstellen und Engpässe
Authors: Kippenberger Johanna Kim
Published: October 2022

Die aktuelle Situation stellt die Lieferketten zahlreicher Konsumgüterunternehmen vor Herausforderungen. Dank einer neu entwickelten Simulationssoftware können nun Schwachstellen und Engpässe abgebildet sowie behoben werden.
Optimismus in schwierigen Zeiten
Authors: Heimig Dieter
Published: October 2022

Die Fleischwirtschaft ist im Exportgeschäft gut unterwegs. Bei den Schweinefleisch-Ausfuhren wird 2021 ein Rekordwert erreicht, die Rindfleisch-Exporte legen fast 8 Prozent zu.
Bens blickt optimistisch in die Zukunft
Authors: Heimig Dieter
Published: October 2022

Der Zerlege-Spezialist Bens NV punktet bei seinen Handelspartnern vor allem mit einem hohen Maß an Flexibilität und gutem Kundenservice.
Kritik von allen Seiten
Authors: Mönch Axel
Published: October 2022

Brüssel. Die EU-Kommission stößt mit ihrem Vorschlag zur Verschärfung der EU-Industrieemissionsrichtlinie auf Widerstand. Nach der Ablehnung im EU-Agrarministerrat kommt nun auch heftige Kritik aus dem Europaparlament. Im Fokus stehen dabei die Einbeziehung der Rinderhaltung und die niedrigen Obergrenzen für Schweine und Geflügel.
Gedeckelte Euphorie
Authors: Vetter Bernhard
Published: October 2022

Frankfurt a.M. Unter sanftem Druck des Bundeswirtschaftsministers hat die Gaspreiskommission eilig einen Zwischenbericht erarbeitet und vorgestellt.
Energiekrise zwingt zu mehr Effizienz
Authors: Schaal René , Fleischman Marco
Published: October 2022

Für die Düngemittelproduktion sind essenzielle Rohstoffe momentan knapp und teuer. Nun ist auf ganzer Linie mehr Effizienz gefragt – dies gilt insbesondere für den Nährstoffeinsatz. Verschiedene Tools können dabei helfen, den zur Verfügung stehenden Dünger möglichst effizient auszubringen.
Epidemiology, risk factors, and prevention of colorectal cancer
Authors: Jung Kyung Uk , Kim Hyung Ook , Kim Hungdai
Published: October 2022

Background: Colorectal cancer remains the fourth most common malignancy in Korea, and has been ranked as the third leading cause of cancer deaths in 2020. This study aims to describe the epidemiologic status of colorectal cancer in Korea, and provide basic data for effective primary and secondary prevention methods by summarizing risk factors and screening tools.Current Concepts: Although colorectal cancer incidence and mortality have decreased in recent years in Korea, it still poses a significant public health burden. From the early 1990s until the mid-2000s, the 5-year relative survival of patients with colorectal cancer in Korea continuously increased. This can be attributed to the successful introduction of the government-led screening program; development of improved surgical techniques, anticancer drugs, and adjuvant treatment; and advances medical resources and infrastructure along with economic growth. However, since the late 2000s, the improvement in survival has stagnated. The coronavirus disease 2019 outbreak has reduced hospital visits and screenings, which is assumed to cause delays in diagnosis, leading to a worse prognosis in the patients. To overcome these obstacles, it is essential to explore modifiable environmental risk factors and appropriate screening test methods in Korea.Discussion and Conclusion: Primary prevention through risk factor modification and secondary prevention using suitable screening programs can reduce the incidence and mortality rates of colorectal cancer.
Surgical treatment for metastatic colorectal cancer
Authors: Park Eun Jung , Baik Seung Hyuk
Published: October 2022

Background: Stage IV colorectal cancer (CRC) exhibits heterogeneous characteristics in tumor extent and biology. The overall survival of patients with metastatic CRC has improved with the development of multimodal treatments and new chemotherapeutic drugs.Current Concepts: Resection of metastatic CRC is performed for liver, lung, or peritoneal metastases. Conversion surgeries to resect oligometastatic lesions have been developed with tumor regression using chemotherapeutic agents. Two-stage hepatectomy has extended the surgical indications for patients with metastatic CRC. Synchronous liver and primary tumor resection can be considered in patients with adequate conditions. Local ablation with radiotherapy can be used to treat lung metastasis. Meanwhile, for treating patients with CRC with peritoneal metastasis, cytoreductive surgery with hyperthermic intraperitoneal chemotherapy can be considered. Surgical treatments should be performed in patients with symptomatic primary tumors with unresectable metastasis. However, in recent studies, primary tumor resection in patients with asymptomatic CRC with synchronous, unresectable metastases did not show overall survival benefits.Discussion and Conclusion: The treatment of metastatic CRC is challenging because of the variable tumor extent and heterogenous characteristics. Tailored surgical treatments and multidisciplinary approaches may improve the survival and quality of life of patients with metastatic CRC.
Robotic surgery for colorectal cancer
Authors: Bae Sung Uk
Published: October 2022

Background: Robotic surgical systems were created partly to solve several constraints of laparoscopic surgery and to offer technical advantages. With a substantial body of evidence demonstrating its efficacy in rectal cancer treatment, robotic surgery will soon become another conventional treatment. However, further investigations and randomized trials focusing on primary endpoints are necessary to establish some advantages of robot-assisted colon surgery.Current Concepts: Da Vinci Single-Site and SP platforms (Intuitive Surgical Inc.) were developed to overcome the shortcomings of single-port laparoscopic surgery. Despite the currently insufficient evidence, it seems that the SP platform addresses several limitations of single-port transabdominal or transanal surgery. Robotic transanal minimally invasive surgery and total mesorectal excision were developed to overcome conventional platforms’ limitations, using wristed instrumentation to enhance dexterity and ergonomics. Studies on the effectiveness and viability of this novel approach are ongoing. The near-infrared fluorescence technique, real-time stereotactic navigation technology, and other surgical data platforms based on artificial intelligence incorporated into the robotic system will play an important role in improving outcomes.Discussion and Conclusion: Robotic systems for advanced colorectal cancer offer technical advantages for complex and precise surgeries. If robotic surgery costs are reduced by expanding its indications and enhancing competition among different robotic platforms, it will provide clinical benefits to more patients and reduce social healthcare costs.
Principles of the use of inhaler devices in asthma treatment
Authors: Kang Sung-Yoon , Min Taek Ki
Published: October 2022

Background: Inhaler therapy is the most critical route of administering drugs in the management of asthma due to its rapid onset of action, better pulmonary efficacy, and reduced risk of side effects, compared with other routes of administration.Current Concepts: Although many physicians and patients believe they know how to use inhaler devices, most do not know the correct techniques. To achieve better and more effective treatment results, the inhalation device should be appropriate for the characteristics and wishes of each patient. Available inhaler devices include pressurized metered dose inhalers, dry powder inhalers, soft mist inhalers, and nebulizers. To improve disease outcomes and treatment adherence, a personalized stepwise approach, based on each patient’s conscious inhalation, inspiratory flow, and hand-lung coordination, is recommended in the selection of the most appropriate device.Discussion and Conclusion: Common problems with inhaler usage include failure to exhale completely before inhaling, insufficient inhalation efforts, and inadequate breath-hold after inhalation. Therefore, continuing education and support are warranted to ensure optimal outcomes and enable patients to improve inhaler usage techniques. Health care providers should also know the devices and develop systems in order to provide comprehensive support to patients in clinical practice.
Survey study on the emotional labor of physicians in Korea
Authors: Kim Jin Suk
Published: October 2022

Background: Currently, research on emotional labor is increasing. The purpose of this study was to measure the level of emotional labor of Korean physicians and analyze its differences according to the physicians’ individual and group characteristics.Methods: The 2020 Korean Physician Survey was conducted from November 19, 2020, to January 10, 2021, through an online questionnaire. Participants were selected from the member database of the Korean Medical Association by stratified quota sampling. The target population was 57,714, out of which 6,507 participants answered the questionnaire. Out of the 6,507 participants, 5,563 were included for the analysis as they were clinically experienced in patient care.Results: It was found that Korean physicians engaged significantly in emotional labor (average score=70.03). Further, the level of emotional labor was high in women and physicians <40 years of age, as well as in fellow clinicians, physicians in clinic, physicians in private medical institutions, and psychiatrists.Conclusion: Education, legal protection, mandatory holidays, and counseling programs might be necessary to manage the emotional labor of physicians.
ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ BƯỚC ĐẦU ĐIỀU TRỊ UNG THƯ PHỔI KHÔNG TẾ BÀO NHỎ GIAI ĐOẠN IV CÓ ĐỘT BIẾN GEN ALK ĐƯỢC ĐIỀU TRỊ BẰNG THUỐC ỨC CHẾ TYROSINE KINASE – CERITINIB
Authors: Hoàng Gia Nguyễn , Hùng Kiên Đỗ
Published: October 2022

Mục tiêu: Nhận xét một số đặc điểm lâm sàng, cận lâm sàng người bệnh ung thư phổi không tế bào nhỏ giai đoạn IV có đột biến gen ALK được điều trị thuốc ức chế tyrosine kinase – ceritinib. Đánh giá đáp ứng điều trị và một số yếu tố liên quan. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả hồi cứu kết hợp tiến cứu trên 69 bệnh nhân ung thư phổi không tế bào nhỏ có đột biến gen ALK, được điều trị bằng thuốc kháng tyrosine kinase – ceritinib từ 1/2019 đến tháng 06/2022, bệnh nhân được đánh giá mức độ đáp ứng theo tiêu chuẩn RECIST 1.1 và liên quan đáp ứng điều trị với một số yếu tố. Kết quả: Tuổi trung bình 52,6 ± 11,5; hay gặp ở nữ giới 52,2%; phần lớn (59,4%) người bệnh không hút thuốc. 63,8% bệnh nhân được điều trị TKIs bước một. Chỉ số toàn trạng kém PS ≥ 2 chiếm 11,5%. Di căn từ 3 cơ quan trở lên chiếm tỷ lệ cao 49,3%. Di căn não gặp tỷ lệ cao 36,2%. Mô bệnh học ung thư biểu mô tuyến là chủ yếu chiếm 89,9%. Xét nghiệm NGS xác định đột biến gen ALK chiếm 55,1%; RT-PCR chiếm 27,5%, nhuộm HMMD 13,0% và FISH 4,3%. 97,1% được thực hiện trên mẫu mô.  Đáp ứng điều trị: Tỷ lệ đạt đáp ứng hoàn toàn 10,1%, đáp ứng một phần 66,8%. Tỷ lệ đáp ứng toàn bộ 76,9%. Tỷ lệ kiểm soát bệnh là 87,0%. Đáp ứng tổn thương di căn hệ thần kinh trung ương đạt hiệu quả cao 72%. Không có sự khác biệt về tỷ lệ đáp ứng liên quan đến độ tuổi, giới tính, tình trạng hút thuốc, điều trị trước đó, chỉ số toàn trạng, tình trạng di căn não. Kết luận: Bệnh nhân ung thư phổi không tế bào nhỏ giai đoạn IV có đột biến gen ALK thường gặp ở tuổi trẻ, nữ gặp nhiều hơn nam, không hút thuốc. Di căn não gặp với tỷ lệ cao và thường di căn nhiều cơ quan. Điều trị bằng thuốc TKIs thế hệ 2 ceritinib có tỉ lệ đáp ứng cao, đặc biệt với tổn thương di căn hệ thần kinh trung ương. Đáp ứng điều trị không có sự khác biệt liên quan đến các đặc điểm lâm sàng.
U MÁU TIM: BÁO CÁO MỘT CA BỆNH HIẾM GẶP
Authors: Quốc Đạt Nguyễn , Thành Đạt Phạm
Published: October 2022

U máu tim là một loại u lành tính cực kỳ hiếm gặp, với tỷ lệ chỉ chiếm 2,8% trong tổng số các loại u tim nguyên phát. Các triệu chứng của khối u thường biểu hiện ở bệnh nhân khó thở, đau tức ngực và ho khan kéo dài. Chẩn đoán có thể được thực hiện bằng siêu âm tim, chụp cắt lớp vi tính hoặc chụp cộng hưởng từ. Phẫu thuật cắt bỏ triệt để được chỉ định ở những bệnh nhân có triệu chứng.  Báo cáo ca bệnh: Chúng tôi báo cáo về một trường hợp tình cờ tìm thấy một khối u nằm ở ngoại tâm mạc bên phải đã được loại bỏ thành công bằng phẫu thuật nội soi toàn bộ. Kết luận: Chẩn đoán giải phẫu bệnh là u máu tim nguyên phát. Trong trường hợp này, u máu đã được cắt bỏ thành công bằng phẫu thuật nội soi. Bệnh nhân ổn định không tái phát.
ĐÁNH GIÁ KẾT QUẢ ĐIỀU TRỊ TS-1 VÀ OXALIPLATIN TRONG UNG THƯ DẠ DÀY GIAI ĐOẠN MUỘN TẠI BỆNH VIỆN K
Authors: Thị Dung Quách , Hồng Thăng Vũ , Thị Hương Giang Nguyễn
Published: October 2022

Mục tiêu: Đánh giá kết quả điều trị ung thư dạ dày giai đoạn muộn tại bệnh viện K bằng phác đồ TS-1 và Oxaliplatin. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả hồi cứu kết hợp tiến cứu BN có chẩn đoán xác định là ung thư dạ dày giai đoạn muộn, không còn khả năng phẫu thuật triệt căn, được điều trị hóa chất bước một phác đồ TS-1 kết hợp Oxaliplatin tại bệnh viện K từ tháng 1/2019 đến hết tháng 2/2022. Kết quả: Sau điều trị hóa chất phác đồ SOX, tỷ lệ đáp ứng hoàn toàn, đáp ứng một phần, bệnh ổn định lần lượt là 3.1%, 53.1% , 9.4%. Thời gian sống thêm không bệnh (DFS) trung bình là 7.19±4.06 tháng. Thời gian sống thêm toàn bộ trung bình đạt 12.03± 3.74 tháng. Tác dụng phụ hay gặp nhất của phác đồ SOX là rối loạn thần kinh ngoại vi 68.8% (trong đó 62.5% độ 1, 6.3% độ 2), tiếp theo là thiếu máu (37.6% trong đó 31.3% độ 1, 6.3% độ 2), hầu hết các tác dụng phụ đều ở mức độ nhẹ. Kết luận: Hóa chất phác đồ SOX là phác đồ hiệu quả trong ung thư dạ dày giai đoạn muộn
PHÂN TÍCH CHI PHÍ TRỰC TIẾP Y TẾ TRONG ĐIỀU TRỊ ĐÁI THÁO ĐƯỜNG TÍP 2 CHO NGƯỜI BỆNH CÓ BẢO HIỂM Y TẾ TẠI BỆNH VIỆN LÊ VĂN THỊNH NĂM 2021
Authors: Thy Nhạc Vũ Hoàng , Đỗ Hồng Nhung Nguyễn , Phước Thành Nhân Lê , Văn Khanh Trần
Published: October 2022

Mục tiêu: Nghiên cứu được thực hiện nhằm phân tích chi phí trực tiếp y tế trong điều trị đái tháo đường típ 2 (ĐTĐ2) cho người bệnh có BHYT tại bệnh viện Lê Văn Thịnh (BVLVT) năm 2021. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang, được thực hiện thông qua việc hồi cứu dữ liệu liên quan của toàn bộ các lượt điều trị ĐTĐ2 có BHYT tại bệnh viện Lê Văn Thịnh trong năm 2021. Số liệu được xử lý và tổng hợp vào Excel, sau đó phân tích bằng phần mềm SPSS. Kết quả: Trong năm 2021, số lượt điều trị ĐTĐ2 có BHYT là 40.455 lượt, với độ tuổi trung bình là 61,0 (±11,6) tuổi; 59,1% là nữ; 69,3% lượt điều trị có 2 bệnh kèm Tăng huyết áp và Rối loạn lipid máu. Tổng chi phí trực tiếp y tế trong điều trị ĐTĐ2 cho người bệnh có BHYT tại BVLVT là 18,8 tỷ đồng, trong đó chi phí sử dụng Insulin là 4,4 tỷ đồng. Chi phí thuốc và chi phí xét nghiệm chiếm tỷ lệ cao hơn các chi phí khác, có giá trị lần lượt là 75,1% và 13,5%. Chi phí trung bình cho một lượt điều trị ĐTĐ2 có BHYT của mẫu nghiên cứu là 4.114.537 ± 3.565.214 đồng/ lượt nội trú và 449.495 ± 246.074 đồng/ lượt ngoại trú. Kết luận: Kết quả phân tích chi phí trực tiếp y tế trong điều trị ĐTĐ2 góp phần cung cấp thông tin trong việc ra quyết định phân bổ và điều chỉnh ngân sách của BVLVT, nhằm sử dụng hợp lý nguồn ngân sách và thực hiện tự chủ tài chính tại BVLVT.
SO SÁNH HIỆU QUẢ KHỞI MÊ, THOÁT MÊ VÀ TÁC DỤNG TRÊN TUẦN HOÀN GIỮA GÂY MÊ KẾT HỢP PROPOFOL TCI VỚI KETAMIN VÀ ETOMIDAT VỚI SEVOFLURAN Ở NGƯỜI CAO TUỔI
Authors: Thị Thanh Huyền Nguyễn , Hữu Tú Nguyễn
Published: October 2022

Mục tiêu nghiên cứu này nhằm so sánh thời gian khởi mê, thời gian hồi tỉnh và ảnh hưởng trên nhịp tim, huyết áp giữa gây mê bằng propofol TCI kết hợp với Ketamin và Etomidat kết hợp với sevofluran ở người cao tuổi. 210 bệnh nhân ≥ 60 tuổi, ASA I-II được ngẫu nhiên chia làm ba nhóm: nhóm 1 (n = 70) khởi mê bằng propofol TCI (Target Controlled Infusion) đặt nồng độ đích tại huyết tương (Cp- plasma concentration); nhóm 2 (n = 70) khởi mê bằng propofol TCI đặt nồng độ đích tại não (Ce - effect site concentration). Cả nhóm 1 và nhóm 2 kết hợp ketamin 0,3 mg/kg, duy trì mê bằng propofol -TCI; nhóm 3 (n = 70) khởi mê bằng etomidat truyền tĩnh mạch tốc độ 0,05 mg/kg/phút, duy trì mê bằng sevofluran. Ba nhóm cùng kết hợp fentanyl 3µg/kg; rocuronium 0,8mg/kg để đặt ống nội khí quản (NKQ). Kết quả: Thời gian chờ mất tri giác, đủ điều kiện đặt ống NKQ, thời gian khởi mê của nhóm 3 ngắn hơn so với nhóm 1 và nhóm 2 (p < 0,01). Tại thời điểm trước khi đặt ống NKQ: huyết áp tâm thu, huyết áp trung bình của nhóm 1 thấp hơn so với nhóm 2 và nhóm 3 với p < 0,05; Sau đặt ống NKQ: tần số tim, huyết áp tâm thu, huyết áp động mạch của nhóm 3 cao hơn so với nhóm 1, nhóm 2 và cao hơn so với thời điểm trước khi khởi mê (p < 0,001). Thời gian đủ điều kiện rút ống NKQ của nhóm 1 và nhóm 2 ngắn hơn nhóm 3.