bluuebunny/crossref_metadata_2025 huggingface dataset:
Modified Drug Delivery Systems for Veterinary Use: Pharmaceutical Development and Applications
Authors: Souto Eliana B. , Santini Antonello , Barbosa Catarina I. , Baldim Iara , Campos Joana R. , Fernandes Ana R. , Mazzola Priscila G. , Andreani Tatiana , Dias Isabel R. , Durazzo Alessandra , Lucarini Massimo , Atanasov Atanas G. , Silva Amélia M.
Published: April 2022

Scientific research in the field of veterinary pharmacology has provided new opportunities for the development of modified release dosage forms, with the aim to improve therapeutic efficacy and reduce animal stress. The formulation of classical drug molecules with advanced biomaterials has become a new approach to increase drug bioavailability and thereby improve the therapeutic outcome. The main reasons for the development of modified drug delivery systems for animal use are the need of reducing the animal stress caused by its handling and administration of the drug and of reducing the cost in financial and chronological terms. This review discusses the most common delivery systems used in veterinary, and the difficulties encountered in innovating therapeutic options in the field.
Distance-based Support Vector Machine to Predict DNA N6-
methyladenine Modification
Authors: Zhang Haoyu , Zou Quan , Ju Ying , Song Chenggang , Chen Dong
Published: April 2022

Background:

DNA N6-methyladenine plays an important role in the restriction-modification
system to isolate invasion from adventive DNA. The shortcomings of the high time consumption and
high costs of experimental methods have been exposed, and some computational methods have
emerged. The support vector machine theory has received extensive attention in the bioinformatics field
due to its solid theoretical foundation and many good characteristics.

Objective:

General machine learning methods include an important step of extracting features. The research
has omitted this step and replaced with easy-to-obtain sequence distances matrix to obtain better
results.

Method:

First sequence alignment technology was used to achieve the similarity matrix. Then, a novel
transformation turned the similarity matrix into a distance matrix. Next, the similarity-distance matrix
was made positive semi-definite so that it can be used in the kernel matrix. Finally, the LIBSVM software
was applied to solve the support vector machine.

Results:

The five-fold cross-validation of this model on rice and mouse data has achieved excellent accuracy
rates of 92.04% and 96.51%, respectively. This shows that the DB-SVM method has obvious
advantages over traditional machine learning methods. Meanwhile, this model achieved 0.943,0.982 and
0.818 accuracy; 0.944, 0.982, and 0.838 Matthews correlation coefficient; and 0.942, 0.982 and 0.840
F1 scores for the rice, M. musculus and cross-species genome datasets, respectively.

Conclusion:

These outcomes show that this model outperforms the iIM-CNN and csDMA in the prediction
of DNA 6mA modification, which is the latest research finding on DNA 6mA.
Temozolomide Resistance: A Multifarious Review on Mechanisms Beyond
O-6-Methylguanine-DNA Methyltransferase
Authors: Rao Vanishree , Kumar Gautam , Vibhavari R.J.A. , Nandakumar Krishnadas , Thorat Nanasaheb D. , Chamallamudi Mallikarjuna Rao , Kumar Nitesh
Published: April 2022

Background:

Chemotherapy with the oral alkylating agent temozolomide still prevails as a
linchpin in the therapeutic regimen of glioblastoma alongside radiotherapy. Because of the
impoverished prognosis and sparse chemotherapeutic medicaments associated with glioblastoma, the
burgeoning resistance to temozolomide has made the whole condition almost irremediable.

Objective:

The present review highlights the possible mechanisms of drug resistance following
chemotherapy with temozolomide.

Method:

The review summarizes the recent developments, as published in articles from Scopus,
PubMed, and Web of Science search engines.

Description:

One of the prime resistance mediators, O‑6‑methylguanine‑DNA methyltransferase, upon
activation, removes temozolomide-induced methyl adducts bound to DNA and reinstates genomic
integrity. In the bargain, neoteric advances in the conception of temozolomide resistance have opened
the door to explore several potential mediators like indirect DNA repair systems, efflux mechanisms,
epigenetic modulation, microenvironmental influences, and autophagy-apoptosis processes that
constantly lead to the failure of chemotherapy.

Conclusion:

This review sheds light on recent discoveries, proposed theories, and clinical developments
in the field of temozolomide resistance to summarize the complex and intriguing involvement of
oncobiological pathways.
Circularly Polarized Triangular Patch Antenna
Authors: Toktas Abdurrahim
Published: April 2022

Background:

Circularly polarized (CP) antenna is an effective choice for wireless systems
due to its insensitivity to the orientations of electromagnetic waves.

Objective:

A novel CP triangular patch antenna (CPTA) system is designed for ultra-wideband
(UWB) applications.

Methods:

The CPTA, with a total size of 40.6 x 40.9 x 1.6 mm3, comprises a triangular patch positioned
on the aperture of a V-shaped ground plane and a feeding network that powers the two corners
of the patch. The network consists of a T-shaped divider with a 50 Ohm microstrip transmission line
(MTL) and two 100 Ohm MTLs, and two matching strips are inserted at the end of the MTLs.

Results:

The antenna system shows UWB performance for both impedance bandwidth (IM-BW) of
4-11 GHz and axial ratio bandwidth (AR-BW) of 3.5-8.0 GHz. A detailed review is further carried
out to manifest the superiority of CPTA over the state-of-the-art technology.

Conclusion:

It thus provides compatible IM-BW and AR-BW for UWB operations due to its optimal
compact design.
Rubbery Polyhydroxyesters based on Polyethylene Glycol Diglycidyl Ether:
Reaction and Vitrimer-like Behavior Catalyzed by Tin Octoate
Authors: Cunha Rodrigo H. , Nele Marcio , Dias Marcos L. , Cunha R.
Published: April 2022

Background:

Polyhydroxyesters prepared from epoxy and organic acids are vitrimers that can rearrange their topology from exchange reactions enhanced by catalysts, forming crosslinked net-works that can be deformed and remolded.

Objectives:

In this work, the curing kinetics and thermal properties of polyhydroxyesters vitrimers based on polyethylene glycol diglycidyl ether (PEGDGE), citric acid (CA), and sebacic acid (SA) in the presence and absence of tin octoate (Sn(Oct)2) were investigated.

Methods:

Differential scanning calorimetry (DSC) non-isothermal experiments and Ozawa models were used for the curing kinetic studies, and thermogravimetry analysis (TGA) and thermomechanical analyses (TMA) were employed to investigate the thermal behavior of the networks.

Results:

The highest curing enthalpy of these exothermic reactions was observed in the binary system PEGDGE:CA without catalyst (326 J/g). The addition of Sn increases the reaction enthalpy for formu-lations with SA and decreases it for formulations rich in CA. The lowest activation energy was shown for the formulation PEGDGE:CA = 3:2 containing 1 mol% of Sn (56 kJ/mol). The polyhydroxyesters presented Tg ranging from -24 to -48 °C, and the Tg decreased when the proportion of SA was in-creased in the formulation. The thermal stability was increased when the SA content increased and de-creased when the content of Sn increased from 1 to 5 mol%.

Conclusion:

Esterification of PEGDGE and organic acids (SA and CA) occurs even in the absence of catalyst, producing rubbery polyesters, but the use of Sn(Oct)2 decreases the curing time. Ternary net-works of polyhydroxyesters containing Sn showed a discontinuity in the thermal expansion around 180°C attributed to exchange reactions, similarly to what was theorized for this class of vitrimer material.
Analytical Methods and GAPI Assessment Used for the Determination of
Toxic Metals in Commercial Cosmetic Products: A Review
Authors: Abbas Ruba Fahmi , Waheb Ali Amer
Published: April 2022

Background:

The toxic metal content of cosmetics causes worry because of the daily and repeated use of these products, which are placed over thin and sensitive areas of the skin such as the face, eyelids, and lips.

Objective:

Toxic metals like Fe, Cr, Hg, Cu, Cd, Ni, and As are determined in various types of cosmetics such as colour cosmetics, hair cosmetics, body and face care products, and herbal cosmetics. Last studies estimate that in commercial cosmetics toxic metals might present in amounts making a risk to human health.

Methods:

Many analysis methods used for determining toxic metals in cosmetics were established. The instruments involving FAAS, ICP-AES, ICP–MS, Hydride generation, Cold vapor, and CE spectrometers with many novel methods were described in this review. Green analytical methods should be developed for determining toxic metals in cosmetics and particularly during the preparation of analytical cosmetic samples.

Results:

The most tools used for assessing analytical protocols related to green analytical chemistry are GAPI (Green Analytical Procedure Index). GAPI gives good information on the safety of analytical chemistry procedures, depending on the five pentagrams shaped with three color symbols that can be used (green, yellow, and red) referring to low, medium to high impact, respectively.

Conclusion:

This review offers an overview, analytical chemistry methods and instruments used for the estimation of toxic metals in cosmetics and their GAPI assessment.
Vesicular Approach Review on Nanocarriers bearing Curcumin and Applications
Authors: Upadhyay Prashant , Singh Deepak , Upadhyay Sukirti
Published: April 2022

Phytoconstituents have been used to treat a variety of human diseases for a long time, but their use in pharmaceuticals is limited because of their low aqueous solubility. Researchers have created vesicular systems to address many of the issues associated with the bioavailability and therapeutic efficacy of poorly water-soluble drugs and target the drug to the desired location in the body. Several vesicular nanocarrier systems have been developed. Review contrasts various vesicular drug delivery systems, including liposomes, sphingosomes, emulsomes, niosomes, ethosomes, virosomes, phytosomes, aquasomes, proniosomes, transfersomes, pharmacosomes. Vesicular drug delivery systems have caused a scientific revolution, which has resulted in the development of novel dosage forms. This review aims to illustrate the applications, advantages, and disadvantages of the vesicular approach as nanocarriers bearing curcumin and widely used in gene delivery, tumor-targeting to the brain, oral formulations, and resolving various problems associated with drug stability and permeability issues. Nanocarriers also has wide application as green nanocomposites and for antitubercular drugs depending on their physical properties.
Drug Delivery Platforms Containing Thermoresponsive Polymers and
Mucoadhesive Cellulose Derivatives: A Review of Patents
Authors: da Silva Jéssica Bassi , dos Santos Rafaela Said , Vecchi Camila Felix , Bruschi Marcos Luciano
Published: April 2022

Nowadays, the development of mucoadhesive systems for drug delivery has gained keen
interest, with enormous potential in applications through different routes. Mucoadhesion characterizes
an attractive interaction between the pharmaceutical dosage form and the mucosal surface. Many polymers
have shown the ability to interact with mucus, increasing the residence time of local and/or systemic
administered preparations, such as tablets, patches, semi-solids, and micro and nanoparticles.
Cellulose is the most abundant polymer on the earth. It is widely used in the pharmaceutical industry
as an inert pharmaceutical ingredient, mainly in its covalently modified forms: methylcellulose, ethylcellulose,
hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methylcellulose, and carboxymethylcellulose
salts. Aiming to overcome the drawbacks of oral, ocular, nasal, vaginal, and rectal
routes and thereby maintaining patient compliance, innovative polymer blends have gained the interest
of the pharmaceutical industry. Combining mucoadhesive and thermoresponsive polymers allows
for simultaneous in situ gelation and mucoadhesion, thus enhancing the retention of the system at
the site of administration and drug availability. Thermoresponsive polymers have the ability to change
physicochemical properties triggered by temperature, which is particularly interesting considering the
physiological temperature. The present review provides an analysis of the main characteristics and applications
of cellulose derivatives as mucoadhesive polymers and their use in blends together with
thermoresponsive polymers, aiming at platforms for drug delivery. Patents were reviewed, categorized,
and discussed, focusing on the applications and pharmaceutical dosage forms using this innovative
strategy. This review manuscript also provides a detailed introduction to the topic and a perspective
on further developments.
Glass and Natural Fiber Composite: Properties and Applications
Authors: Mann G.S.
Published: April 2022

The ecological concerns and issues such as recycling of plastic products and environmental care are increasingly important to handle the present situation of climate change. As a consequence of growing environmental awareness surrounding society a there is a great interest in the research on more eco-friendly materials that are derived from renewable resources. Therefore, natural composites also known as green bio composites have received attention from researchers and industries to develop biodegradable materials by using natural fibres, those possess outstanding degradable and sustainable properties. Because of its superior properties such as high specific strength, low weight, low cost, reasonably good mechanical properties, non-abrasive, eco-friendly, and bio-degradable characteristics, natural fibres these materials are useful to help researchers, scientists and industries to develop different biodegradable and eco-friendly products. This chapter explored the mechanical properties of natural-glass fibre reinforced polymer composites by considering database from google scholar and other relevant sites.
Applications of Polymers in Ophthalmology
Authors: Tewari A.K.
Published: April 2022

Ophthalmology focuses on health issues related to eye, vision, anatomy and concerned ailments. Hitherto, a variety of materials such as ceramic, metal, glass and polymers have been extensively explored that modify optic adherence, residing time, targeted release with minimum downsides. Modern ophthalmic implants including contact lens, ocular endotamponades, viscoelastic replacements etc. are developed by polymers owing to their inherent virtues such as biocompatible with eye tissues, ease of manufacturing, flexible in operation, cost effective etc. The chapter emphasizes on biodegradable (chitosan, poly-lactic acid) and non- biodegradable (PVA, silicones) polymeric ocular preparations such as artificial cornea, orbital ball, glaucoma drainage device etc.
Valid Virtual Reality Applications for Commercial Kitchen Safety Training
Authors: Saad Mazni , Mohamad Najib Muhammad Danial Haiqal , Pratt Thomas James
Published: April 2022

The rise in the number of workers in gastronomy tourism has coincided with an increase in workplace accidents. New workers lack hazard identification abilities and fail to recognize dangerous events in the workplace. Thus, a two-fold goal has been established: (1) design and develop VR applications for spotting risks in the kitchen workplace, and (2) validate the VR application's effectiveness. The invention involved the 360-degree camera and VR software, and it was validated with multiple experts who had long working experience. The VR technology was found noteworthy as it received positive acceptance in the hospitality business.
Keywords: Virtual Reality; Workplace Safety; Food Service Safety; Employee Safety
eISSN: 2398-4287 © 2022. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v7i19.3207
Use of a Paid Digital Marketing Campaign to Promote a Mobile Health App to Encourage Parent-Engaged Developmental Monitoring: Implementation Study
Authors: Arshanapally Suraj , Green Katie , Slaughter Karnesha , Muller Robert , Wheaton Demeika
Published: April 2022

Background

The internet has become an increasingly popular medium for parents to obtain health information. More studies investigating the impact of paid digital marketing campaigns for parents on promoting children’s healthy development are needed.

Objective

This study aims to explore the outcomes of a paid digital marketing campaign, which occurred from 2018 to 2020, to promote messages about parent-engaged developmental monitoring and ultimately direct parents to the Centers for Disease Control and Prevention’s (CDC’s) Milestone Tracker app, a mobile health (mHealth) app developed by the CDC.

Methods

The paid digital marketing campaign occurred in 3 phases from 2018 to 2020. In each phase, 24 to 36 marketing messages, in English and Spanish, were created and disseminated using Google’s Universal App Campaigns and Facebook Ads Manager. Outcomes were measured using impressions, clicks, and install data. Return on investment was measured using click-through rate (CTR), cost per click, and cost per install metrics.

Results

The Google-driven marketing messages garnered a total of 4,879,722 impressions (n=1,991,250, 40.81% for English and n=2,888,472, 59.19% for Spanish). The messages resulted in a total of 73,956 clicks (n=44,328, 59.94% for English and n=29,628, 40.06% for Spanish), with a total average CTR of 1.52% (2.22% for English and 1.03% for Spanish). From these clicks, there were 13,707 installs (n=9765, 71.24% for English and n=3942, 28.76% for Spanish) of the CDC’s Milestone Tracker app on Google Play Store. The total average cost per install was US $0.93 across all phases. The phase 3 headline “Track your child’s development” generated the highest CTR of 3.23% for both English and Spanish audiences. The Facebook-driven marketing messages garnered 2,434,320 impressions (n=1,612,934, 66.26% for English and n=821,386, 33.74% for Spanish). The messages resulted in 44,698 clicks (n=33,353, 74.62% for English and n=11,345, 25.38% for Spanish), with an average CTR of 1.84% (2.07% for English and 1.38% for Spanish). In all 3 phases, animated graphics generated the greatest number of clicks among both English and Spanish audiences on Facebook when compared with other types of images.

Conclusions

These paid digital marketing campaigns can increase targeted message exposure about parent-engaged developmental monitoring and direct a parent audience to an mHealth app. Digital marketing platforms provide helpful metrics that can be used to assess the reach, engagement, and cost-effectiveness of this effort. The results from this study suggest that paid digital marketing can be an effective strategy and can inform future digital marketing activities to promote mHealth apps targeting parents of young children.
Health-Related Quality of Life of HIV-Positive and HIV-Negative Pregnant Women in an Impoverished Area: Cross-sectional Study (Preprint)
Authors: Qu Shuiling , Wang Ailing , Wang Xiaoyan , Yang Yehuan , Pan Xiaoping , Zhang Tong
Published: April 2022

BACKGROUND

Liangshan prefecture of Sichuan province was an impoverished mountainous area in China, where the annual number of HIV-positive pregnant women accounted for approximately 10% of China’s total population in the decades before 2020. In general, pregnant women living here are likely to be physically and mentally different from those in other places.

OBJECTIVE

This study aims to explore the health-related quality of life (HRQoL) of pregnant women living with HIV in an impoverished area.

METHODS

From December 2018 to January 2019, HIV-positive and HIV-negative parturients within 18 months after delivery were recruited in Liangshan Prefecture, Sichuan Province. Questionnaires were designed to collect their demographic data, while the EuroQol 5-Dimension, 3-Level questionnaire was used to measure their HRQoL when they were in the second trimester from 4 to 6 months of pregnancy, and their quantitative health scores were converted to corresponding healthy utility values by using the Chinese Utility Value Integral System (time trade-off coefficient).

RESULTS

A total of 250 pregnant women (133 HIV-positive and 117 HIV-negative) were enrolled in the study. Among them, 55 (41.35%) and 75 (64.10%) of HIV-positive and HIV-negative pregnant women self-reported full health (healthy state 11111), respectively. The median health utility value of the 250 pregnant women was 0.961 (IQR –0.046 to 0.961), and those of the HIV-positive and HIV-negative pregnant women were 0.875 (0.424-0.961) and 0.961 (IQR –0.046 to 0.961), respectively. We observed a significant difference only in the dimension of anxiety or depression between the two groups (P=.002) and no significant difference in the distribution of health utility indices between the two groups in terms of maternal age, education level, occupation, annual household income, prenatal care visits, family size, and medical insurance category. Multivariate ordinal logistic regression analysis showed that age (odds ratio [OR] 0.62, P<.05) and prenatal care visit (OR 0.29, P<.01) were independent risk factors for health status.

CONCLUSIONS

Most pregnant women self-reported satisfactory HRQoL in this impoverished mountainous area. HIV-negative pregnant women had an edge over HIV-positive pregnant women, and there were significant differences in anxiety or depression dimensions between the two groups.
Where Do Oncology Patients Seek and Share Health Information? Survey Study (Preprint)
Authors: Freeman Eric , Patel Darshilmukesh , Odeniyi Folasade , Pasquinelli Mary , Jain Shikha
Published: April 2022

UNSTRUCTURED

N/A
Analisis Pengaruh Variasi Tegangan Terhadap Oxyhydrogen (Hho) Generator
Authors: Handayani Yanolanda Suzantry , Priyadi Irnanda
Published: April 2022

Konsumsi energi di Indonesia meningkat rata-rata sebesar 7% per tahun seiring dengan meningkatnya jumlah penduduk, kegiatan ekonomi, dan perkembangan industri. Beberapa jenis energi di Indonesia diantaranya adalah minyak bumi, gas alam, batu bara, tenaga air, dan panas bumi. Energi merupakan salah satu komponen penting bagi kelangsungan hidup manusia. Pada umumnya masyarakat masih banyak bergantung pada ketersedian sumber daya alam energi fosil yang sifatnya un-renewable, terutama minyak bumi yang semakin lama semakin berkurang jumlahnya. Energi alternatif yang dapat diperbarui perlu terus diteliti karena ketergantungan terhadap bahan bakar fosil masih sangat tinggi. Padahal bahan bakar fosil akan terus menipis, ketergantungan yang tidak teratasi akan menyebabkan  krisis energi. Suplemen Oxyhydrogen (HHO) pada kendaraan bermotor berbahan bakar gasoline mampu meningkatkan efisiensi mencapai 14 % hingga 18%. Selain sebagai suplemen HHO masih dapat dikembangkan menjadi bahan bakar utama yang bersih dan ramah lingkungan. Untuk memproduksi HHO diperlukan energi listrik, sehingga perlu mengetahui karakteristik generator HHO, salah satunya dengan modifikasi menggunakan elektroda pelat berlubang. Penelitian ini akan megimplementasikan sebuah alat elektrolisis yang mampu menghasilkan gas hidrogen dari air (H2O) dengan cara yang sederhana dan praktis, dan menganalisa efektivitas dari alat tersebut sehingga kedepannya mampu menghasilkan suatu alat elektrolisis dengan tingkat efisiensi yang tinggi. Hasil dari penelitian ini adalah Variasi tegangan listrik berpengaruh terhadap hasil produksi Oxyhydrogen (HHO) Generator. Generator kering HHO bersel sebelas berdimensi sel 75mm x 75mm dengan jarak gap 3mm yang digunakan menghasilkan 290 mL/min, 455,5 mL/min, 650 mL/min dari variasi tegangan  12V, 14V dan 16V.
Implementasi Filter Kalman pada Sensor Jarak Berbasis Ultrasonik
Authors: Hudati Imroatul , Nugroho Ervan Surya Aby , Resty Nerissa Diana
Published: April 2022

Intisari – Kehadiran noise pada pengukuran dari perangkat sensor dapat memberikan dampak yang besar terhadap penurunan performa sistem kendali. Kehadiran dari noise tersebut bisa diakibatkan dari banyak faktor, misalnya terkait  rendahnya spesifikasi perangkat, gangguan sinyal luar (eksternal), kerumitan dari pengukuran yang dilakukan. Dengan dampak yang diberikan tersebut maka perlu adanya pencegahan atau upaya untuk mendapatkan respons kendali dari sistem dengan performa yang baik. Terlebih apabila sensor tersebut diterapkan pada palang pintu kereta api yang pastinya akan mendapat banyak noise dari lingkungan sekitar. Adapun salah satu solusinya adalah dengan membuat desain sebuah filter sinyal. Pada penelitian ini, desain dari Algoritma Filter Kalman (AFK) dibuat untuk digunakan pada sensor ultrasonik. Filter tersebut dibuat untuk mengatasi derau pengukuran dari sensor. Jenis sensor ultrasonik yang digunakan adalah HC-SR04 yang dapat mendeteksi jarak pengukuran mulai dari 3 cm sampai dengan 350 cm. AFK tersebut diimplementasikan menggunakan microcontroller ATMEGA328P yang ada pada board Arduino Uno. Algoritma tersebut diuji dengan lima jarak pengukuran yang berbeda-beda. Hasilnya menunjukkan bahwa AFK mampu mereduksi derau pengukuran sensor ultrasonik. Analisa data menunjukkan bahwa variabel standar deviasi pengukuran memiliki penurunan yang signifikan. Hal tersebut dibuktikan dengan nilai rata-rata dari standar deviasi dari kelima pengujian turun dari 0.3831 menjadi 0.0173 atau mengalami penurunan sekitar 95,5%.Kata kunci : sensor jarak, derau, sinyal, Filter Kalman, HC-SR04
Experimental production of lithic artefacts: Developing understanding; developing engagement
Authors: Piprani John
Published: April 2022

This paper is reflective and discusses the results of a process experiment designed to develop understanding of a particular British Early Upper Palaeolithic stone tool technology. The technology in question is the Lincombian, and the discussion breaks down into three main parts. The first part argues that raw material availability and practitioner performance can be influential factors within the modern experimental reproduction process. When these issues were factored in for this experiment it became clear that early phase debitage materials reflected a process of interpretation, not replication. The second substantive part of this discussion focuses upon the final phase of the experimental process. Selection criterion for assessing finished artefacts was tightly constrained by archaeologically derived data. It is argued therefore that when finished artefacts fell within these assessment criteria the final phase of the process was akin to replication. Consequently, debitage associated with the final phase can provide useful analogue material to fill gaps in our understanding of this Lincombian technology. The final section is summative and returns to the issue of performance. It argues that practitioner performance facilitates audience engagement. Engagement is valuable for communicating understanding to both specialist and non-specialist audiences. The paper concludes by arguing that a rigorously evaluated experimental process can be used twice: firstly, as a tool for generating materials to develop our understanding; secondly, as an engaging performance to communicate understanding to specialist and non-specialist audiences.
Temps, mémoire et altérité en technologie lithique: synthèse et perspectives de l’approche technogénétique française
Authors: De Weyer Louis , Pérez Antonio , Hoguin Rodolphe , Forestier Hubert , Boëda Eric
Published: April 2022

L'approche technogénétique dans le domaine des études en technologie lithique préhistorique trouve son origine à la fin des années 1980. Les approches traditionnelles comme de la typologie à la technologie productionnelle ont eu tendance à aborder les objets de la préhistoire à travers leurs dimensions socioculturelle et économique, sans vraiment considérer l’existence d’une technogenèse antérieure à ces contingences. L’appréhension de cette dimension technogénétique en préhistoire convoquera à la fois la philosophie et l’anthropologie des techniques pour amener à une double approche des artefacts: une approche technogénétique de l’objet lithique selon les critères techniques de sa genèse; et une approche psychosociale de l’objet selon les critères propres à sa production artisanale au sein d’un système technique majeur. L’objectif de cet article est d’identifier deux existences fondamentales constituantes de l’objet technique, l’une interne (technogénétique) avec des lignées techniques et l’autre externe (psychosociale) avec des trajectoires techniques. La distribution spatio-temporelle de l’altérité technique préhistorique sur différents continents a logiquement amené à de nouvelles questions, constats et de nouveaux critères d’analyse. Sur cette base, notre démarche visera à revisiter les principaux axes conceptuels des fondements de l’approche technologique, à préciser les anciennes questions tout en développant de nouvelles expertises. À travers l’application de concepts clés comme celui de temps, de mémoire et d’altérité, une méthodologie d’ensemble sera également rediscutée et proposera une ligne de fuite épistémologique.
Pleistocene volcanism along the margins of the Canal de Ballenas transform fault, Gulf of California
Authors: Martín-Barajas Arturo , Schmitt Axel K. , Weber Bodo , López-Martínez Margarita
Published: April 2022

Pleistocene subaerial volcanism along the margins of the Ballenas Channel, northern Gulf of California, is represented by two morphologically young dacite dome complexes exposed at the opposite edges of sheared continental crust: Isla Coronado in coastal Baja California, and the Lobera volcanic complex in west-central Isla Ángel de la Guarda. Single crystal zircon U-Pb crystallization ages of Coronado and Lobera volcanoes range between ca. 250 and 1000 ka, indicating maximum ages for the eruptions. Eruption ages are directly constrained by an 40Ar/39Ar whole-rock age of 692 ± 164 ka for one of the lava units in the Lobera volcanic complex. Trace elements in Pleistocene zircon indicate continental affinity, which supports radiogenic (Nd, Sr) isotopic data that were modeled using different mixing and AFC scenarios indicating a MORB-type primary magma with significant (~10–20 %) crustal assimilation involving tonalitic basement of the eastern Peninsular Ranges Batholith.
Vida material y espiritual en los curatos de San Salvador y Sonsonate en el último cuarto del siglo XVIII
Authors: González Torres Julián
Published: April 2022

La presente investigación analiza un conjunto de disposiciones, tomadas por el arzobispo Cayetano Francos y Monroy, en torno a la administración y el uso del dinero y los bienes de las cofradías y hermandades, en los curatos de San Salvador y Sonsonate, en el antiguo Reino de Guatemala, a partir de las visitas pastorales que realizó en los años de 1781, 1782, 1790 y 1791. La metodología consistió en el análisis y la contextualización del contenido de los autos de las visitas pastorales, prestando especial interés a la información concerniente al dinero y los bienes de aquellas corporaciones. El estudio revela que la ceremonia de la visita pastoral reafirmaba el valor y la supremacía del poder espiritual en los pueblos de San Salvador y Sonsonate; demuestra que la economía de las cofradías y hermandades sostenía el tiempo y el espacio sacros de los pueblos; al mismo tiempo expone algunas resistencias de los parroquianos a las disposiciones tomadas por el arzobispo.
Lucha y resistencia indígena en el México colonial
Authors: Soriano Hernández Silvia
Published: April 2022

Este libro presenta una parte de la historia de México resaltando el carácter rebelde de los indígenas, su lucha por desprenderse del dominio explotador, sus constantes fracasos y nuevas incursiones, su inconformidad con una vida de sometimiento y mal trato, de desprecio y sojuzgación; larga resistencia que muchas veces se tradujo en rebelión.
El pensamiento lascasiano de la conciencia de América y Europa
Authors: Ruiz Bonifaz Augusto G. , Soriano Hernández Silvia , González Casanova H. Pablo , Esponda Jimeno Víctor Manuel , Matos Arévalo José A. , Mosquera Aguilar Antonio , Rodríguez Pérez Margarita J. , Chiong Guevara Teresa , Aubry Andrés , Romo Cedano Pablo , Robles Ramírez Ángel , Fernández Ríos Olga , Márquez Piñero Rafael , Ordóñez Cifuentes José , Monal Isabel , Sánchez Macgregor Joaquín , Barrios Ruiz Walda E.
Published: April 2022

Esta publicación cuestiona a Bartolomé de Las Casas sobre como se propone objetar todo un sistema de dominación en cuyo centro político él mismo continúa ubicado, y que durante el pasado vivió experiencias que lo contradicen siendo esclavista primero, y como dominico esclavista después.
Los canguros mexicanos: aspectos importantes de su ecología y conservación
Authors: Montero-Bagatella Sandra H. , Cervantes Fernando A.
Published: April 2022

Los desiertos mexicanos son habitados por las carismáticas ratas canguro. Estos roedores destacan tanto por su diversidad como por los diferentes servicios que brindan a los ecosistemas. Algunas de las especies del grupo están en peligro de extinción debido a las severas transformaciones de su hábitat. En este artículo se abordarán los principales aspectos biológicos y ecológicos de las ratas canguro en México, así como los algunos de los riesgos de conservación a los que se están enfrentando.
¡Qué dientes tan grandes tienes! Un vistazo a la dieta del lobo mexicano
Authors: Reyes-Díaz Jorge L. , Lara Díaz Nalleli E. , López-González Carlos A.
Published: April 2022

El lobo mexicano ha regresado a las serranías mexicanas, pero su ecología y conflictos potenciales con los ganaderos lo hacen vulnerable a la extinción. La presencia de estos carnívoros en vida silvestre permite estudiar su dieta, para enriquecer las estrategias para su conservación. Los excrementos de los lobos guardan en su interior restos no digeridos de las presas que comen, y el pelo es utilizado para identificar qué especies de animales consumieron. Durante nueve años, se colectaron excrementos de lobo en el noroeste de México. La dieta del lobo mexicano en nuestro país registra una diversidad de 25 presas silvestres y tres domésticas, mientras que en Estados Unidos se han reportado 15 y una, respectivamente. Los venados y el cerdo son los componentes principales, en biomasa y frecuencia, en la dieta de los lobos en México, seguidos del ganado bovino, ardillones, zorrillos y conejos. El consumo de cerdo forma parte de las estrategias de reintroducción, entre aquellas que disminuyen el consumo de ganado, pero para que éstas funcionen es necesario que los ganaderos aumenten la vigilancia y protección del ganado. De esta forma, lobos y otros depredadores dejarán de ser considerados dañinos y podrán coexistir con el ser humano.
Herramientas matemáticas y políticas para reducir el efecto invernadero
Authors: Munguía López Aurora del Carmen , Ponce Ortega José María
Published: April 2022

En la actualidad, uno de los retos más importantes es desarrollar acercamientos para abordar problemas como la creciente generación de emisiones en el sector energético, debido a las consecuencias negativas que esto puede tener en nuestra vida diaria. En relación con estas problemáticas, se ha propuesto formular modelos matemáticos para evaluar políticas de carbono en sistemas de generación de energía no convencionales, que permitan reducir las emisiones. Estas políticas de carbono involucran impuestos y bonos de carbono para disminuir las emisiones; y algunos de los sistemas no convencionales incluyen plantas de potencia que utilizan combustión indirecta con un sistema de cultivo de algas y plantas de potencia de doble propósito, que incluyen el uso de biocombustibles y energía solar. El objetivo de este trabajo es mostrar cómo estas herramientas matemáticas y políticas permiten obtener soluciones óptimas que incluyen relaciones complejas entre aspectos económicos, ambientales, y sociales. Esto facilita la toma de decisiones en esquemas no convencionales de generación de energía.
Personalized AI Dietitian and Fitness Trainer
Authors: Gawli Swarangi , Ubale Ishan , Damekar Sudha
Published: April 2022

Abstract: Exercising is the most important thing to live a healthy life. To be free from injuries and getting the most from our workout proper form of exercise is important. Doing too much repetition and over training can cause muscle soreness. Unendingly doing exercise incorrectly could eventually cause severe future injuries. The rest between the sets should be optimum depending on the repetition of the exercise, what muscle group is being trained and the load that is being put in the muscle. Maximum Muscle hypertrophy is achieved with the correct form of exercise. The goal of the project is to build an exercise repetition counter and form corrector in a way so the optimum growth can be achieved with the help of cutting edge technology. The whole project is written in python. Simple easy to use tkinter GUI is used, Computer vision for live video input, media pipe for building machine learning solutions and numpy for mathematical calculations. Our system is built on the most recent advancements in deep learning for build cause estimation. We tend to the area units that are able to observe and find errors in user’s activity (pose) by effectively supporting some threshold deviation between the limb angles. If a person is doing exercises with the help of this system, the user's form is checked (corrections in form also will be given if any) repetition’s status and count is displayed. Along with this the AI dietitian calculates the maintenance calories, BMR, etc. This will increase muscle hypertrophy and reduce the risk of injury. Keywords: Exercise, Form corrector, Machine learning, Numpy, Tkinter
Desenho universal para aprendizagem na EB: o que dizem as produções científicas
Authors: Da Silva Pereira Danielly Raquel , Massaro Munique
Published: April 2022

O objetivo deste artigo é analisar a aplicabilidade do Desenho Universal para a Aprendizagem na Educação Básica brasileira, a partir de produções científicas. Foi realizada uma pesquisa bibliográfica com o recorte entre 2015 e 2019, com a palavra-chave Desenho Universal para a Aprendizagem, na base de dados Google Acadêmico. Assim, 15 estudos foram selecionados e analisados a partir de três categorias de análise. Os resultados apontaram que as práticas realizadas foram ações pontuais, a maioria com resultados positivos, e mostraram a possibilidade de aplicar os princípios.
Estatuto e saberes da docência na educação profissional: questões inaugurais dos anos 1940
Authors: Pedrosa José Geraldo , Duenhas Flávia Oliveira , Ramos Nívea Maria Teixeira
Published: April 2022

O artigo focaliza a docência na educação profissional no Brasil dos anos 1940, com base nos escritos de Francisco Montojos (1900–1981) e Lourenço Filho (1897–1970). Nessa década, com os fenômenos industrial e urbano, surgiram situações inéditas para a educação profissional, entre as quais a preparação da docência de cultura técnica ou da docência de oficina. O artigo examina ideias de dois intelectuais que atuaram nesse período e identifica as questões relativas ao estatuto próprio da docência na educação profissional e a circulação de ideias anglo-americanas e do escolanovismo.
Uma trajetória de contradições e disputas: Formação docente na ETFPel/CEFET-RS/IFSul - Campus Pelotas
Authors: Porto Júnior Manoel José , Araujo Jair Jonko , Eslabão Leomar da Costa
Published: April 2022

Este trabalho tem por objetivo examinar a trajetória histórica da formação de professores no IFSul/Campus Pelotas, a partir de nossa experiência docente e de documentos disponíveis. Pretende contribuir na construção de uma resistência diante dos retrocessos que enfrentamos, com as Diretrizes Curriculares Nacionais para a Formação Inicial de Professores para a Educação Básica e a Base Nacional Comum, definidas pela Resolução Conselho Ncional de Educação nº 02/2019. Examina-se as alterações na composição do currículo, evidenciando a tradição epistemológica adotada na instituição, incompatível com o pragmatismo e utilitarismo que pretende se impor.
História e Cultura Afro-Brasileira e Africana na formação inicial de professoras(es) de Pedagogia
Authors: Loro Alexandre Paulo , De Souza Flávia Bezerra
Published: April 2022

O presente estudo objetiva analisar como a História e Cultura Afro-Brasileira e Africana são abordadas no currículo escolar da Educação Básica. Participaram do estudo gestores/as de dezenove escolas da região Oeste de Santa Catarina e, para tanto, utilizou-se como técnica para o levantamento de dados a entrevista. As diferenças étnico-raciais presentes no exercício da docência, por vezes, reforçam os processos coloniais e as relações de poder/saber vigentes. Conclui-se que uma das alternativas de superação é por meio da formação inicial de professores/as, capacitando-os/as/ para atuar na perspectiva da diversidade cultural, ao colocar sob tensão estereótipos e preconceitos étnico-raciais, apontando para a necessidade de pensar em outros paradigmas.
Indícios para se pensar a permanência escolar: memórias narradas do Programa de Educação Integrada do Mobral
Authors: Freitas Marinaide Lima , Da Silva Jailson Costa , Torres Andresso Marques
Published: April 2022

O artigo apresenta os achados de uma pesquisa realizada no sertão de Alagoas, focalizada em compreender como os sertanejos se apropriaram das ações de continuidade da escolarização, implementadas pelo Programa de Educação Integrada (PEI) pertencente ao Mobral (1967-1985) – época da ditadura civil-militar. Baseou-se nos pressupostos metodológicos da História Oral. As narrativas apontaram que a permanência dos sujeitos na escola, após a conclusão do PEI, deu-se por intermédio de ações individuais, cujos esforços por uma vida melhor marcaram os percursos dos/as interlocutores/as.
Pesquisas sobre o Proeja produzidas no Estado de Santa Catarina
Authors: Agne Sandra Aparecida Antonini , Lopes Andréa Isensee
Published: April 2022

Neste artigo foram analisadas 19 pesquisas, produzidas entre 2008 e 2019, no âmbito dos programas de pós-graduação das instituições de ensino superior de Santa Catarina, e que trataram do Programa Nacional de Integração da Educação Profissional com a Educação Básica na modalidade de Jovens e Adultos – PROEJA. Após identificadas, tais pesquisas foram situados no que concerne a seu contexto de produção, seus objetos e principais fundamentos teóricos. Com isso, nossa finalidade foi de compreender o atual estado de produção do conhecimento acerca desse programa, em território catarinense. Como considerações, aponta-se a necessidade de mais pesquisas sobre tal iniciativa, bem como da reafirmação da própria política que garantiu o PROEJA, pois, como evidenciou-se, sua oferta está além da universalização e do direito à educação: trata-se de um processo em disputa, tanto a respeito da oferta pelas escolas e pela garantia financeira governamental, quanto pelo espaço de produção acadêmica.
O currículo da Educação de Jovens e Adultos e a formação dos sujeitos
Authors: Sousa Roberto Fernandes , Dantas Tânia Regina , Conceição Ana Paula da Silva
Published: April 2022

Este artigo tem como tema o currículo da Educação de Jovens e Adultos – EJA. Nosso intuito é compreender como o currículo pode legitimar os conhecimentos que os sujeitos constroem e validam na sua interação com o território de Vila de Abrantes, no município de Camaçari-BA. O objetivo geral é apreender as relações entre o território e os currículos instituídos e implementados na EJA. Os sujeitos dessa pesquisa são estudantes, professores/as, coordenadores/as pedagógicos/as e gestores/as da EJA de escolas da rede municipal. Metologicamente, optou-se por uma pesquisa qualitativa, com inspiração etnográfica. Os resultados do trabalho evidenciam que os sujeitos têm uma significativa apreensão acerca dos saberes emanados do território, fruto das suas experiências pessoais, sociais e laborativas e que percebem oportunidades para que estes saberes sejam incorporados aos conteúdos curriculares da EJA. Os achados apontam para a necessidade de uma inserção sistemática dos temas nos programas de formação continuada dos/as profissionais da EJA no território.
Artefatos político-pedagógicos de combate à desigualdade de gênero e sexualidade nos processos educativos
Authors: Vigano Samira de Moraes Maia , Laffin Maria Hermínia Lage Fernandes
Published: April 2022

O presente artigo objetiva situar uma análise sobre um conjunto de artefatos político-pedagógicos, de orientações e de legislações produzidos no contexto de lutas dos movimentos sociais, dos espaços educativos e de suas efetivações nas esferas governamentais que contribuem para o combate à desigualdade de gênero e de sexualidade, bem como para o respeito à diversidade. Incialmente, apresenta-se a discussão com a problematização das desigualdades em relação às pessoas lésbicas, gays, bissexuais e transgêneros – LGBTs, na sequência, o debate sobre direitos humanos e o reconhecimento por parte da sociedade brasileira sobre as questões da diversidade de gênero e de sexualidade em diferentes documentos legais e de orientações sociais e educativas, finalizando a reflexão sobre alguns materiais teóricos voltados às questões dessa diversidade de gênero e de sexualidade com o objetivo de fomentar a formação docente e as práticas educativas. Conclui-se que tais artefatos constituem importantes apoios no reconhecimento às questões da diversidade de gênero e de sexualidade, de construção de práticas democráticas e de respeito no âmbito dos processos educativos.
DAMPAK INSENTIF PAJAK PERUMAHAN TERHADAP POTENSI PENERIMAAN PAJAK NEGARA DAN PENINGKATAN PENDAPATAN MASYARAKAT: KASUS PROVINSI SULAWESI SELATAN
Authors: Irawan Towaf Totok
Published: April 2022

Until now the government and private sector have not been able to address the backlogof 13.5 million housing units for ownership status and 7.6 million units for residentialstatus. The high price of land has led to the high price of the house, so that lowincomecommunities (MBR) is not able to reach out to make a home purchase. In addition to thehigh price of land, tax factors also contribute to the high price of the house. Thegovernment plans to issue a policy for the provision of tax incentives, ie abolish VAT onhomeforming material transaction. This policy is expected to house prices becomecheaper, so the demand for housing increases, and encourage the relevant sectors tointensify its role in the construction of houses. It is expected to replace the lost taxpotential and increase incomes. Analysis of the impact of tax incentives housing topotential state revenue and an increase in people's income, especially in South Sulawesiprovince is using the table IO because in addition to looking at the role each sector canalso see the impact on taxes (income tax 21 Pph 25Pph, VAT), and incomes (wage).Althoughintheshorttermimpactisstillsmall,butveryrewardinginthelongrun.