bluuebunny/crossref_metadata_2025 huggingface dataset:
Evolutionary plasticity of SH3 domain binding by Nef proteins of the HIV-1/SIVcpz lentiviral lineage
Authors: Zhao Zhe , Fagerlund Riku , Tossavainen Helena , Hopfensperger Kristina , Lotke Rishikesh , Srinivasachar Badarinarayan Smitha , Kirchhoff Frank , Permi Perttu , Sato Kei , Sauter Daniel , Saksela Kalle
Published: November 2021

The accessory protein Nef of human and simian immunodeficiency viruses (HIV and SIV) is an important pathogenicity factor known to interact with cellular protein kinases and other signaling proteins. A canonical SH3 domain binding motif in Nef is required for most of these interactions. For example, HIV-1 Nef activates the tyrosine kinase Hck by tightly binding to its SH3 domain. An archetypal contact between a negatively charged SH3 residue and a highly conserved arginine in Nef (Arg77) plays a key role here. Combining structural analyses with functional assays, we here show that Nef proteins have also developed a distinct structural strategy—termed the "R-clamp”—that favors the formation of this salt bridge via buttressing Arg77. Comparison of evolutionarily diverse Nef proteins revealed that several distinct R-clamps have evolved that are functionally equivalent but differ in the side chain compositions of Nef residues 83 and 120. Whereas a similar R-clamp design is shared by Nef proteins of HIV-1 groups M, O, and P, as well as SIVgor, the Nef proteins of SIV from the Eastern chimpanzee subspecies (SIVcpzP.t.s.) exclusively utilize another type of R-clamp. By contrast, SIV of Central chimpanzees (SIVcpzP.t.t.) and HIV-1 group N strains show more heterogenous R-clamp design principles, including a non-functional evolutionary intermediate of the aforementioned two classes. These data add to our understanding of the structural basis of SH3 binding and kinase deregulation by Nef, and provide an interesting example of primate lentiviral protein evolution.
DATA ENCRYPTION ALGORITHM AES BY USING BLOCKCHAIN TECHNOLOGY: A REVIEW
Authors: Hidayat Taufik , Mahardiko Rahutomo
Published: November 2021

Blockchain is used as encryption algorithm in cryptocurrency, but less researches are found to study blockchain for data encryption. Data encryption is needed to protect the data from data theft. We know about data encryption, there are RSA, LEAP, AES, and other algorithms. This research proposed a review in AES algorithm for data encryption within blockchain technology. The research process is followed by determining library, then creating relevant questions and criteria. For good opportunity in the future, this paper generated suggestions and opportunities so that better research can be established in data encryption.
A Comparison of Burnout Experienced by Family and Consumer Sciences Teachers With Other Content Teachers During COVID- 19 Remote Teaching
Authors: Durr Tony , Graves Nicole A. , Wilson Alison
Published: November 2021

During the spring of 2020, K-12 schools were turned upside-down. The COVID-19 pandemic essentially forced all schools across the nation to close their doors and move their learning environments online. The switch to remote learning put a great deal of stress and responsibility on teachers
at all levels. The content taught by family and consumer sciences (FCS) teachers presented those teachers with unique challenges that differentiated them from other content teachers in programs such as math, language arts, and social studies. With a sample of 97 teachers from Midwestern states,
this study found that FCS teachers reported higher levels of depersonalization and lower feelings of personal accomplishment.
Modelling the ZalaZONE Proving Ground: a benchmark of State-of-the-art Automotive Simulators PreScan, IPG CarMaker, and VTD Vires
Authors: Gangel Kálmán , Hamar Zoltán , Háry András , Horváth Áron , Jandó Gábor , Könyves Balázs , Panker Dániel , Pintér Krisztián , Pataki Márton , Szalai Mátyás , Szalay Zsolt , Tettamanti Tamás , Tihanyi Viktor , Tóth Bálint , Varga Balázs , Viharos Zsolt János
Published: November 2021

In our days, simulation based development is a core element of vehicle engineering, especially considering highly automated or fully autonomous vehicles. Accordingly, the paper presents a benchmark of three different automotive simulators: PreScan, IPG CarMaker, and VTD Vires. The three software tools were applied for the same goal, namely, modelling the ZalaZONE Proving Ground of Hungary for vehicle testing. The paper aims to highlight the experiences while creating the virtual models by presenting and comparing the relevant software features and providing suggestions for scientific or practical application.
Reversed Myth and Negative Symbols of Narcissus in Mother-Son Relationship in Hayashi Fumiko’s Narcissus
Authors: Asmarani Ratna
Published: November 2021

The famous myth of Narcissus is about a mythical handsome young man who indifferently rejects the love of the nymph Echo leading to Echo’s broken heart and untimely death and his being cursed to excessively adore his own handsome reflection on the pond till his death. The short story entitled Narcissus written by Hayashi Fumiko is intriguing because its title calls to mind the famous myth of Narcissus. However, this short story portrays the myth of Narcissus from a unique perspective. Thus, the aims of this paper are to analyse the reversed myth and negative symbols of Narcissus as reflected in the mother-son relationship in the short story. To support the analysis various psychological understandings of the myth of Narcissus are used as well as various understandings of the symbols of the flowers called Narcissus. The methods of research used are a comprehensive combination of textual-contextual methods as well as library research and qualitative research. The textual method focuses on the intrinsic aspects relevant to the focus of analysis, such as character, conflict, and setting, while the contextual method borrows the psychological concepts of the term Narcissus and the symbolic meaning of the flowers named Narcissus. The result shows that the mother-son relationship clearly portrays the reversed myth in the matter of the gender roles, the type of relationship, and the ending of the relationship. Another result shows that all the symbols related to the flowers of Narcissus turn into negative meanings in the sort of story entitled Narcissus by Hayashi Fumiko. In short, the short story writer turns upside down both the myth and the symbols resulting in an engaging story full of hidden meanings to be interpreted
Potensi Reduksi Emisi GRK dan Kelayakan Finansial dari Teknologi Hidrotermal untuk Pengolahan Sampah di Kabupaten Tangerang
Authors: Ayuvitari Rania Salsabila , Wijayanti Pini
Published: November 2021

Peningkatan konsentrasi gas rumah kaca (GRK) di atmosfer telah menimbulkan efek pemanasan global. Salah satu kontributor emisi GRK adalah penumpukan sampah di TPA tanpa pengolahan lebih lanjut. TPA Jatiwaringin di Kabupaten Tangerang diprediksi akan mengalami overcapacity, sehingga diperlukan mitigasi untuk mengurangi sampah di TPA, salah satunya dengan teknologi hidrotermal. Namun dalam penerapan teknologi hidrotermal membutuhkan biaya yang tinggi. Penelitian ini bertujuan untuk mengestimasi potensi emisi GRK sebelum adanya proyek hidrotermal, mengestimasi potensi reduksi emisi GRK setelah adanya proyek hidrotermal, menganalisis kelayakan finansial dari proyek hidrotermal. Penelitian ini menggunakan metode Clean Development Mechanism (CDM) AMS-III.E untuk mengestimasi potensi reduksi emisi GRK proyek hidrotermal dan analisis cashflow untuk mengevaluasi kelayakan finansialnya. Hasil penelitian ini menunjukkan emisi baseline pada tahun 2021 diestimasi sebesar 18.766 t CO2 e dan akan meningkat menjadi 21.865 t CO2 e (16,5%) pada tahun 2030. Emisi proyek diestimasi sebesar 5883 t CO2 e per tahun. Rata-rata persentase potensi reduksi emisi GRK dari proyek hidrotermal tahun 2021-2030 sebesar 70,94% (Skenario 2 putaran per hari) dan 68,26% (Skenario 3 putaran per hari). Proyek hidrotermal juga layak secara finansial, dengan syarat produk hidrotermal yaitu Refused Derived Fuel (RDF) dapat terjual setidaknya 72% dan jumlah iuran masyarakat yang terkumpul minimal 50% dari target penerimaan iuran. ABSTRACTAn increase in the atmospheric concentrations of greenhouse gases (GHGs) produces global warming effect. One of GHGs emissions contributors is waste accumulation of in the landfill. Jatiwaringin landfill in Tangerang Regency is predicted to reach overcapacity. Therefore, mitigation measures are required to reduce such waste. One of potential measures is hydrothermal treatment technology for urban scale, but its implementation is costly. This study aims to: estimate the potential GHGs emissions prior the hydrothermal project, estimate the potential GHGs emission reduction after the project, and analyze the financial feasibility of the project. This study employs Clean Development Mechanism (CDM) method i.e., AMS-III.E to estimate the GHGs emissions reduction potential of hydrothermal projects and cashflow analysis to evaluate the project financial feasibility. The results show that the baseline emissions in 2021 are estimated at 18,766 t CO2 e and would increase to 21,865 t CO2 e (16.5%) in 2030. The potential project emissions are estimated at 5883 t CO2 e per year. The GHGs emission reductions could reach 70.94% (2 batches per day) and 68.26% (3 batches per day) within 2021-2030. Furthermore, the hydrothermal project would be financially feasible, if the hydrothermal product i.e., Refused Derived Fuel (RDF) are sold at least 72% and the cumulative households-contribution is at least 50% of the target.
Chondroblastoma of the Temporal Bone: A Case Report and Literature Review
Authors: Obtulovičová Katarína , Sičák Marián , Kališ Adrian , Buday Tomáš
Published: November 2021

Introduction: Temporal bone chondroblastoma is a rare, locally aggressive tumour originating from immature cartilage, which recurs to a high degree. Treatment is surgical. Radiotherapy is reserved for recurrence. We describe a case of a 15-year-old-boy choosing a conservative surgical approach with reconstruction of the posterior canal wall. This study aims to report a rare pediatric case. Methods: A literature review was performed to better understand temporal bone chondroblastomas, to describe their histopathological and radiological characteristics and to establish the optimal surgical and non-surgical treatments. The research of previous published data was done using PubMed with keywords mentioned below. Results: Authors present a case of a 15-year-old boy with hearing impairment and facial nerve palsy. Conservative surgery with reconstruction of the tympanic membrane and posterior wall of the external auditory canal, restoring the hearing has been performed. We did not administer any adjuvant therapies. No sign of recurrence was observed 1 year after primary surgery. Facial nerve function is normal, and hearing is satisfactory. Conclusion: Chondroblastomas account for less than 1% of primary bone tumours. Temporal bone chondroblastoma is rare, locally aggressive, with a high prevalence of recurrence. This study describes specific histopathological and radiological findings, the chosen surgical approach and follow-up to improve the management and the prognosis of patients affected with this particular clinical entity.
Self-Driving Vehicles Using End to End Deep Imitation Learning
Authors: Nabil Ashraf , Kassem Ayman
Published: November 2021

Autonomous Driving is one of the difficult problems faced the automotive applications. Nowadays, it is restricted due to the presence of some laws that prevent cars from being fully autonomous for the fear of accidents occurrence. Researchers try to improve the accuracy and safety of their models with the aim of having a strong push against these restricted Laws.

Autonomous driving is a sought-after solution which isn’t easily solved by classical approaches. Deep Learning is considered as a strong Artificial Intelligence paradigm which can teach machines how to behave in difficult situations. It proved its success in many differ domains, but it still has sometime in the automotive applications.

The presented work will use the end-to-end deep machine learning field in order to reach to our goal of having Full Autonomous Driving Vehicle that can behave correctly in different scenarios. CARLA simulator will be used to learn and test the deep neural networks. Results will show not only performance on CARLA’s simulator as an end-to-end solution for autonomous driving, but also how the same approach can be used on one of the most popular real datasets of automotive that includes camera images with the corresponding driver’s control action.
Invasive bacterial diseases in northern Canada, 1999 to 2018
Authors: Huang Grace , Martin Irene , Tsang Raymond S , Demczuk Walter H , Tyrrell Gregory J , Li Y Anita , Dickson Catherine , Reyes-Domingo Francesca , Squires Susan G
Published: November 2021

Background: The International Circumpolar Surveillance (ICS) program conducts surveillance on five invasive bacterial diseases: pneumococcal disease (IPD), group A streptococcus (iGAS), Haemophilus influenzae (Hi), meningococcal disease (IMD) and group B streptococcus (GBS). Invasive bacterial diseases have a higher burden of disease in northern populations than the rest of Canada. Methods: To describe the epidemiology of invasive bacterial diseases in northern Canada from 1999 to 2018, data for IPD, iGAS, Hi, IMD and GBS were extracted from the ICS program and the Canadian Notifiable Diseases Surveillance System (CNDSS) and analyzed. Results: The annualized incidence rates for IPD, iGAS, Hi, GBS and IMD were 23.3, 10.5, 8.9, 1.9 and 1.1 per 100,000 population, respectively. The incidence of IPD, iGAS and Hi serotype b were 2.8, 3.2 and 8.8 times higher, respectively, in northern Canada than in the rest of Canada. Rates of disease decreased statistically significantly for IPD (β=−0.02) and increased statistically for iGAS (β=0.08) and Hi serotype a (β=0.04) during the study period. In Northern Canada, the annualized incidence rates for IPD, iGAS and Hi were statistically higher for Indigenous residents than for non-Indigenous residents. The highest incidence rates were among the very young and older age groups. Conclusion: Invasive bacterial diseases represent a high burden of disease in Canada’s northern populations. Indigenous peoples, children and seniors are particularly at risk.
Szlachetni szaleńcy czy zwykli złodzieje? Wybrane aspekty problemu kradzieży książek na przestrzeni wieków
Authors: Kubiaczyk Monika
Published: November 2021

This paper analyzes the phenomenon of book theft, sometimes referred to somewhat frivolously as bibliokleptomania. The essential goal is to outline the motives behind such practices and, based on that, develop a typology of book thieves.
Piłka nożna jako narzędzie wyjaśniania świata, rec. książki: Anita Werner, Michał Kołodziejczyk, Mecz to pretekst. Futbol, wojna, polityka
Authors: Kubiaczyk Filip
Published: November 2021

Piłka nożna jako narzędzie wyjaśniania świata, rec. książki: Anita Werner, Michał Kołodziejczyk, Mecz to pretekst. Futbol, wojna, polityka
Pine-cones for moss: a late Byzantine/early modern Greek version of ATU 1525E, Thieves steal from one another
Authors: Braccini Tommaso
Published: November 2021

Two Greek authors, Georgios Sphrantzes (fifteenth century) and Makarios Melissourgos-Melissenos (sixteenth century) refer to a variant of the type ATU 1525E, Thieves steal from one another. It is the oldest known version, and it is remarkably close to the variants later attested in Georgia and the Balkans (an area that clearly shows the features of the Byzantine cultural heritage). The comparison also makes it possible to clarify and confirm the meaning of an obscure word used in the oldest version, that of Sphrantzes, where pine-cones (koukoutzella) and moss are at the center of the exchange.
A füstölgő meddőhányóktól a globális közlekedésig. Beszélgetés Erdősi Ferenccel [Interjú]
Authors:   TEMI Fried Művelődési Ház Közhasznú Alapítvány, Herczeg Alexandra , Moró Dávid Róbert ,   Pécsi Tudományegyetem, Természettudományi Kar, Tésits Róbert ,   Pécsi Tudományegyetem, Természettudományi Kar, Földrajzi és Földtudományi Intézet
Published: November 2021

Ferenc Erdősi was born on April 19, 1934 in Pécs, Hungary. He first graduated from the University of Szeged as a teacher of Geography and Geology, and then from the Faculty of Humanities at the Eötvös Loránd University as a teacher of History. He became the doctor of Hungarian Academy of Sciences in 1989 and was appointed university professor in 1993. In the last two decades, he has dealt with transport geography and the study of the territorial effects of telematics. In 2004, he was awarded the Gábor Baross Prize and the Knight’s Cross of the Order of Merit of the Republic of Hungary. In 2010, he was awarded the Officer’s Cross. The subsequently semi-structured interview was conducted in September 2021, at his home. The purpose of this discussion was to gain a better understanding of the important moments in the professor’s life, the milieu that played a role in shaping his professional career. Our aim was also to present the virtues, challenges and tasks of Hungarian Geography through the experiences of this conversation.
Effects of actual and perceived financial literacy skills on financial well-being at retirement
Authors: Voros Zsofia , Szabo Zoltan , Schepp Zoltán , Kehl Daniel , Kovacs Oliver Bela
Published: November 2021

THE AIMS OF THE PAPER

Studies have not explained fully how financial literacy, decision making skills and the diverse forms of financial literacy overconfidence interact with each other to explain households’ actual and perceived financial well-being at retirement. This study aims to map the interactions among these constructs within the elderly population.

METHODOLOGY

In the framework of a larger assessment on subjective well-being and its antecedents at retirement, three hundred retired people between the age of 65 and 85 filled out a questionnaire in their home in Hungary in March 2019.

MOST IMPORTANT RESULTS

Elderly people are overconfident in their financial literacy skills both on absolut and relative levels. Percieved financial literacy is a better predictor of financial situation than actual financial literacy. However, financial literacy overconficence relative to others harms elderly people’s financial situation. Subjective financial well-being is mainly driven by the actual financial situation. Decision making skills play an important role in the calibration of financial literacy skills and have an additional direct effect on the subjective level of financial well-being. Our outcomes reinforce that it is indeed worth promoting programs helping elderly people acquiring domain-specific financial knowledge. These programs may lead to better financial situation and higher self-efficacy. Moreover, our findings imply that it would be worthwhile for programs to concentrate on the calibration of financial knowledge vis-á-vis others.

RECOMMENDATIONS

To complement the mainstream literature, the study examines the forms of overconfidence and their effects on financial well-being separately and concentrates on the elderly population.

Acknowledgements: The project was financed by the European Social Fund: Comprehensive Development for Implementing Smart Specialization Strategies at the University of Pecs (EFOP-3.6.1.- 16-2016-00004). Declarations of interest: none.
Selective Increase of Correlated Activity in Arc-Positive Neurons after Chemically Induced Long-Term Potentiation in Cultured Hippocampal Neurons
Authors: Jiang Yuheng , VanDongen Antonius M. J.
Published: November 2021

The activity-dependent expression of immediate-early genes (IEGs) has been utilized to label memory traces. However, their roles in engram specification are incompletely understood. Outstanding questions remain as to whether expression of IEGs can interplay with network properties such as functional connectivity and also if neurons expressing different IEGs are functionally distinct. In order to connect IEG expression at the cellular level with changes in functional connectivity, we investigated the expression of 2 IEGs, Arc and c-Fos, in cultured hippocampal neurons. Primary neuronal cultures were treated with a chemical cocktail [4-aminopyridine (4AP), bicuculline (Bic), and forskolin] to increase neuronal activity, IEG expression, and induce chemical long-term potentiation (LTP). Neuronal firing is assayed by intracellular calcium imaging using GCaMP6m and expression of IEGs is assessed by immunofluorescence staining. We noted an emergent network property of refinement in network activity, characterized by a global downregulation of correlated activity, together with an increase in correlated activity between subsets of specific neurons. Subsequently, we show that Arc expression correlates with the effects of refinement, as the increase in correlated activity occurs specifically between Arc-positive neurons. The expression patterns of the IEGs c-Fos and Arc strongly overlap, but Arc was more selectively expressed than c-Fos. A subpopulation of neurons positive for both Arc and c-Fos shows increased correlated activity, while correlated firing between Arc+/cFos– neurons is reduced. Our results relate neuronal activity-dependent expression of the IEGs Arc and c-Fos on the individual cellular level to changes in correlated activity of the neuronal network.
A One-Shot Shift from Explore to Exploit in Monkey Prefrontal Cortex
Authors: Achterberg Jascha , Kadohisa Mikiko , Watanabe Kei , Kusunoki Makoto , Buckley Mark J. , Duncan John
Published: November 2021

Much animal learning is slow, with cumulative changes in behavior driven by reward prediction errors. When the abstract structure of a problem is known, however, both animals and formal learning models can rapidly attach new items to their roles within this structure, sometimes in a single trial. Frontal cortex is likely to play a key role in this process. To examine information seeking and use in a known problem structure, we trained monkeys in an explore/exploit task, requiring the animal first to test objects for their association with reward, then, once rewarded objects were found, to reselect them on further trials for further rewards. Many cells in the frontal cortex showed an explore/exploit preference aligned with one-shot learning in the monkeys' behavior: the population switched from an explore state to an exploit state after a single trial of learning but partially maintained the explore state if an error indicated that learning had failed. Binary switch from explore to exploit was not explained by continuous changes linked to expectancy or prediction error. Explore/exploit preferences were independent for two stages of the trial: object selection and receipt of feedback. Within an established task structure, frontal activity may control the separate processes of explore and exploit, switching in one trial between the two.

SIGNIFICANCE STATEMENTMuch animal learning is slow, with cumulative changes in behavior driven by reward prediction errors. When the abstract structure a problem is known, however, both animals and formal learning models can rapidly attach new items to their roles within this structure. To address transitions in neural activity during one-shot learning, we trained monkeys in an explore/exploit task using familiar objects and a highly familiar task structure. When learning was rapid, many frontal neurons showed a binary, one-shot switch between explore and exploit. Within an established task structure, frontal activity may control the separate operations of exploring alternative objects to establish their current role, then exploiting this knowledge for further reward.
Indicators of Ukrainian Industries’ Competitiveness Considering Factor of Human Capital
Authors:   Lviv Polytechnic National University, Oleksiv Ihor , Mirzoieva Diana ,   Lviv Polytechnic National University
Published: November 2021

The aim of the article is to determine the types of economic activity of Ukraine with high export competitiveness, taking into account human capital. The stages of creation of an export product were elaborated, the main resource of which is human capital, the indicator of its efficiency – labor intensity, the results – the volume of output and the share of value added in output, and the foreign economic result – the share of exports. As a result of hierarchical cluster analysis, five clusters were defined, the current state of which was characterized by statistical data. In particular, outpacing coefficients were calculated for each cluster. As the result, recommendations were provided for clusters and the Ukrainian economy as a whole.
History of Kharkiv school of endocrinology
Authors:   Kharkiv Medical Academy of Postgraduate Education, Goncharova О.А.
Published: November 2021

The article contains data on the creation and formation in Kharkiv of the V.Ya. Danilevsky Institute of Endocrine Pathology of the National Academy of Medical Sciences of Ukraine, its role in the development of domestic and world endocrinology. The personal contribution of the Institute’s scientists to the development of fundamental and applied aspects of endocrinology is specified. The role of the Institute in creating an organizational system of endocrinological care in Ukraine and in solving the problem of postgraduate training of endocrinologists for Ukraine is presented.
A citizen of Byzantium in the «valley of the shadow of death» (Psalm 22:4).
Authors:   V.N. Karazin Kharkiv National University, Sorochan S.B.
Published: November 2021

The article attempts to generalize the ideas of specialists in Byzantine Studies about the causes and levels of mortality in Byzantium. Studies show that the average life expectancy was quite typical of ancient and medieval society and did not differ from the Neolithic era. Usually death occurred within 20-40 years, in the most productive period of life. Thus, Byzantine society remained quite young. With a high birth rate, the number of children who reached adulthood usually did not exceed two per family. Premature deaths were caused by epidemics of infectious diseases, environmental, natural disasters, accidents, murders, and wars. In the last case, 90% of the deaths were due to disease, starvation and cold, and not to the battle. In general, the Byzantine rulers, representatives of secular and ecclesiastical authorities behaved very wisely, trying to avoid excessive violence and human loss.
The initiator of the Kharkiv Medical Society, professor W.F. Grube
Authors:   Ukrainian Academy of Medical History, Petrova Zh.P.
Published: November 2021

The article considers the biography and professional path of the founder of the Kharkiv Medical Society, Professor W.F. Grube. The connection between his social and clinical activities is shown. Professor W.F. Grube headed the Kharkiv Medical Society (HMT) for 22 years. His position and work have identified the development of HMT in the clinical, scientific and industrial fields. As a public figure, professor W.F. Grube enjoyed authority among colleagues, government officials and the general public.
Yu.R. Pensky — surgeon and dean of the medical faculty of Kharkiv University.
Authors:   Kharkiv National Medical University, Pertseva Zh.M.
Published: November 2021

The article is devoted to the memory of Yu.R. Penskii, a famous surgeon and clinician of the late 19th — early 20th century and the last dean of Kharkiv University, who made a significant contribution to the development of the higher medical school in Kharkiv.
Scientific heritage of Leonardo da Vinci and modern cardiology
Authors:   Kharkiv Medical Academy of Postgraduate Education, Korzh O.M.
Published: November 2021

Leonardo da Vinci’s research on human organs attracted his lifelong interest. His diagrams and sketches of the skull, skeleton, muscles and major organs make up countless pages of writing. Even more space in his personal diaries is occupied by theories about how all these human organs function. Modern autopsies show that he was correct in many aspects of his functioning. In 2020, scientists managed to uncover the secret of the human heart of Leonardo da Vinci. It turned out that a network of muscle fibers called trabeculae lines the inner surface of the heart and, as shown in its drawings, affects the favorable functioning of the heart.
Progressive multifocal leukoencephalopathy after a kidney transplantation: based on literature review and own clinical case
Authors:   Kharkiv Medical Academy of Postgraduate Education, Litovchenko T.A. , Vostrotin O.V. ,   Kharkiv Medical Academy of Postgraduate Education, Tondiy O.L. ,   Kharkiv Medical Academy of Postgraduate Education, Lebedynets V.V. ,   Kharkiv Medical Academy of Postgraduate Education, Kolinko Yu.L. ,   Kharkiv Medical Academy of Postgraduate Education
Published: November 2021

This article discusses the development of progressive multifocal leukoencephalopathy after a kidney transplantation on the background of immunosuppressive therap. It’s the example of a clinical case. Based on the literature review, it is known that progressive multifocal leukoencephalopathy is a progressive demyelinating disease of the central nervous system, which is caused by reactivation of the latent JC virus; such reactivation usually occurs in immunodeficient conditions. In the clinical case, the appearance of this disease was demonstrated and its severe and potentially fatal multifocal lesion of the white matter of the brain was proved. The disease was developed on the background of immunosuppressive therapy after a history of kidney transplantation. The understanding of the clinical course of progressive multifocal leukoencephalopathy, the absence of specific neurological manifestations and course were expanded. It is noted that MRI results in addition to the clinical picture and anamnestic data help to establish the diagnosis of PML and make a differential diagnosis. Progressive multifocal leukoencephalopathy in transplant recipients receiving immunosuppressive therapy have an unfavorable prognosis.
On the Interplay between Q2 and t Dependences in Exclusive Diffractive Production of Real Photons and Vector Mesons in ep Collisions
Authors: Fiore R. , Jenkovszky L.L. , Lavorini A. , Magas V.K.
Published: November 2021

We show how the familiar phenomenological way of combining the Q2 (photon virtuality) and t (squared momentum transfer) dependences of the scattering amplitude in Deeply Virtual Compton Scattering (DVCS) [1, 2] and Vector Meson Production (VMP) [2] processes can be understood in an off-mass-shell generalization of dual amplitudes with Mandelstam analyticity [3]. By comparingdifferent approaches, we managed also to constrain the numerical values of the free parameters.
Hoarseness
Authors: Adam Henry
Published: November 2021

Key Points

Most pediatric hoarseness is benign, reversible, and self-limited.Some causes of hoarseness are progressive, malignant, and even life-threatening.Stridor accompanying hoarseness should be investigated urgently.The age of the patient is a useful way to organize the differential diagnosis.
OPTIMIZATION OF DATA TRANSFER IN THE INTERNET OF THINGS ENVIRONMENT
Authors:   Department of Computers and Informatics, Faculty of Electrical Engineering and Informatics, Technical University of Košice, Letná 9, 042 00 Košice, Slovak Republic, PETIJA Rastislav , JAKAB František , FECIĽAK Peter , MICHALKO Miroslav
Published: November 2021

This article deals with the implementation and experimental verification of the suitability of the TinyIPFIX protocol for data transmission in the Internet of Things environment. The work was devoted to the creation of three main components, namely TinyIPFIX exporter, collector, and mediator. The implementation of these tools made it possible to extend the possibility of monitoring a common network with an IoT environment. The experiments confirmed the success of the implementation of the protocol based on standards and pointed out the suitability of the implementation of the TinyIPFIX protocol mainly due to its optimized processes, which save up to 72% of bandwidth consumption compared to the IPFIX protocol when transmitting one data unit. Thanks to the modular approach during implementation, it is possible to deploy the protocol in the environment regardless of the transport technology. The created solution can therefore also be used in UAV sensor networks.
NOVEL SOFTWARE IN MATLAB DESIGNED FOR UWB SENSOR-BASED LOCALIZATION OF PEOPLE IN 2D AND 3D SPACE
Authors:   K-Mlab organizational unit of Ilmsens GmbH, University science park TECHNICOM, Nemcovej 5, 040 01 Kosice, Slovak Republic, ŠVINGÁL Michal , KOCUR Dusan ,   Department of Electronics and Multimedia Communications, Faculty of Electrical Engineering and Informatics, Technical University of Kosice, Letna 9, 042 00 Kosice, Slovak Republic, FORTES Jana ,   Department of Electronics and Multimedia Communications, Faculty of Electrical Engineering and Informatics, Technical University of Kosice, Letna 9, 042 00 Kosice, Slovak Republic
Published: November 2021

Detection, localization, and tracking of people in 2D or 3D space using Ultra-wideband (UWB) short-range sensors is a subject of worldwide intensive research. In this paper, we describe a proposal for a novel software called UWB-PerLoc-2D3D. This software has been created in a MATLAB programming environment and designed to process UWB radar signals for the purpose of movement monitoring of human targets in 2D and 3D space. We present an evaluation of the proposed software properties as well as examples of its utilization in practice.
Birds of Parque Nacional do Caparaó, Atlantic Forest, southeastern Brazil
Authors: Ferreira Carolina Demetrio , Baptista Michelle Noronha da Matta
Published: November 2021

Parque Nacional do Caparaó is located in the Serra do Caparaó in the southeastern region of Brazil. It lies on the border between the states of Espírito Santo and Minas Gerais. It is a large fragment of Atlantic Forest vegetation, with altitudinal variation from 630 to 2,892 m. We present an annotated list of bird species found in the park based on data collected from 2012 to 2018. We recorded 216 species, including 66 endemic, 22 threatened, and 17 newly recorded species. To complete the list of species, we added data available in several bibliographic sources and digital databases, bringing the total number of bird species in the park to 348 and including 98 endemic and 33 threatened species. This work is the first to present an updated list of birds for the park, and the data presented show the importance of this protected area for conservation of birds in the region.
Improvement of covered wagons of the “East-West” type by sectioning with a partition
Authors: Fomin Oleksij , Lovska Alyona , Klymash Andriy , Keremet Mykhailo
Published: November 2021

The dynamic loading and strength of the frame of the “East-West” type covered wagon were determined. To increase the efficiency of operation of covered wagons in international traffic, it is proposed to improve their frames. This improvement consists in using a sectional partition in the body in order to divide it into two separate sections. This allows the transportation of different goods in one wagon, and therefore decreasing empty mileage.
The longitudinal loading of the covered wagon frame was determined. The case of shunting impact was considered. The studies were carried out in a flat coordinate system. The loading mode of the frame of the covered wagon in the empty and loaded states was considered. The acceleration acting on the covered wagon frame in the loaded state was 0.37g, empty – 0.42g, which does not exceed the standard values. The wagon motion is rated “excellent”.
The main strength indicators of the covered wagon frame were determined. The calculation was made by the finite element method. It was found that the maximum equivalent stresses are concentrated in the area of interaction of the center sill with the bolster beam and amounted to 340 MPa, which is lower than the yield stress of the material. Maximum displacements occur in the middle of the frame beams and are about 12 mm. The natural vibration frequencies of the covered wagon frame were calculated.
The research will help to increase the efficiency of using covered wagons in international traffic. Also, the research results can be useful developments in the creation of innovative rolling stock structures
Ontologiczne podstawy antropologii bł. Antonia Rosminiego
Authors: Orzeł Tomasz
Published: November 2021

Bł. ks. Antonio Rosmini (1797–1855) to niezwykle wszechstronny i płodny pisarsko myśliciel włoski. Jego spuścizna naukowa obejmuje prawie 100 książek z różnych dziedzin: od filozofii poprzez teologię aż po nauki polityczne. Był niezrozumiany przez swoje pokolenie. Jego dwie prace: O pięciu ranach Kościoła Świętego (Delle cinque piaghe della santa Chiesa) oraz Konstytucja według sprawiedliwości społecznej (La Costituzione secondo la giustizia sociale) zostały wpisane na Indeks ksiąg zakazanych. Po wielu latach zrehabilitowany, został ogłoszony błogosławionym w 2007 r.Domeną jego zainteresowań była filozofia, a szczególnie metafizyka i antropologia. Dzięki stworzeniu spójnej i oryginalnej koncepcji osoby jest nazywany ojcem europejskiego personalizmu. Niniejszy artykuł jest próbą przedstawienia rosminiańskiej wizji osoby ze szczególnym zwróceniem uwagi na ontologiczne podstawy jego teorii.
Network Interaction Monitoring System with IoT Devices Connected
Authors:   Volgograd State University, Demyanov Gleb , Sadovnikova Natalya ,   Volgograd State Technical University
Published: November 2021

The Internet of Things is a concept of a computer network of physical objects equipped with built-in technologies for interacting with each other or with the external environment, considering the organization of such networks as a phenomenon that can restructure economic and social processes, eliminating the need for human participation from part of actions and operations. IoT technology has had a significant impact on the development of information technology and other industries. According to Forbes, the Internet of Things market is expected to reach $520 billion in 2021, up from $235 billion in 2017, indicating a continued growth in demand for such devices in the future. Gartner Research also estimates that the number of devices connected to the Internet will reach 25 billion by 2021, up from 8.4 billion in 2017. Network with IoT devices connected is an indispensable prey for intruders. There are many ways to attack IoT devices. In this article, the authors have identified several methods of protection. Among them, network interaction monitoring through the analysis is highlighted. The paper also describes how to apply this method in practice.
Investigation of the Interaction of Carbon Dioxide with Modified Functional Groups of Nanotubes
Authors:   National Research Technological University “MISIS”, Kozhitov Lev , Zaporotskova Irina ,   Volgograd State University, Boroznina Natalia ,   Volgograd State University, Boroznin Sergey ,   Volgograd State University, Akatiev Vladimir ,   Volgograd State University
Published: November 2021

The article presents a theoretical study of the possibility of interaction of one of the most common substances in nature – carbon dioxide – with modified functional carboxyl and amine groups of carbon nanotubes and borocarbon nanotubes of the BC5 type. The article analyzes the results of the interaction and provides a comparative analysis of the efficiency of the sorption interaction of a nanosystem with a carbon dioxide molecule. The performed studies prove the implementation of a weak physical sorption interaction between a nanosystem consisting of a carbon nanotube, a boundary-modified amine group, and a carbon dioxide molecule. This allows us talking about a possible sensory interaction that will allow using such a complex to detect a micro amount of a substance-carbon dioxide. Based on this, it can be concluded that modified carbon nanotubes can be elements of sensors for determining the quality of indoor air, act as probes for cantilevers of atomic force microscopes and other devices. Recommendations are given for further use of the results as a basis for creating a highly sensitive new-generation sensor device for detecting micro-quantities of substances.
Changes in Intestinal Microbiota Composition in 1–5 Years Old Children with Atopic Dermatitis: Cross Sectional Study
Authors: Yudina Julia V. , Aminova Alfiia I. , Prodeus Andrey P. , Korsunskiy Anatoly A.
Published: November 2021

Background. Atopic dermatitis (AD) arouses high research interest these days due to its significant morbidity rate. The most crucial risk factor for its development is the intestinal microbiota composition. The correlation of this factor with the development of AD in children requires further study.

Objective. The aim of the study is to perform comparative analysis of the intestinal microbiota in 1–5 years old children with AD and conditionally healthy children via 16S-sequencing of ribosomal RNA (rRNA) of bacterial genes.

Methods. We have conducted cross sectional study. 60 children with diagnosed AD and 15 conditionally healthy children aged from 1 to 5 years were surveyed. Intestinal microbiota was examined via 16S-sequencing of rRNA of bacterial genes.

Results. The intestinal microbiota in children with AD and conditionally healthy children has statistically significant differences. Despite the absence of significant differences in species richness of compared groups, children with AD had the elevation in the metagenome of Proteobacteria; Bacilli and Gammaproteobacteria classes; Enterococcaceae and Veillonellaceae families; Eggerthella, Dialister and Enterobacter genus; as well as the decrease in the relative value of Actinobacteria, Bacteroidetes, Verrucomicrobia; Bacteroidales and Bifidobacteriales orders; Bifidobacteriaceae, Bacteroidaceae, Erysipelotrichaceae families; Lachnoclostridium, Roseburia, Prevotella, Coprococcus, Ruminococcus, Faecalibacterium, Bifidobacterium, Bacteroides genus; decrease of Bifidobacterium longum, Faecalibacterium prausnitzii, Bacteroides fragilis.

Conclusion. It was revealed that the intestinal microbiota of children with AD has significant differences in taxonomic composition with the microbiota of conditionally healthy children. Elevation of Proteobacteria, Bacilli and Gammaproteobacteria classes, Eggerthella, Dialister and Enterobacter genus can be the risk factor for this disease development, whereas decrease of such bacteria as Verrucomicrobia, Bacteroidales and Bifidobacteriales can aggravate atopic symptoms. Thus, the need for further study of intestinal microbiota in children with AD is justified to establish the correlation of these bacteria with the disease course.
Glycemic index studies in rice (Oryza sativa L.) varieties developed by ANGRAU
Authors: Kumari S. Divya Prasanna , Devi G. Nirmala , Chamundeswari N.
Published: November 2021

Twenty popular rice varieties developed by ANGRAU obtained from Regional Agricultural Research Station (RARS), Maruteru during Kharif – 2019, were screened for chemical quality traits viz., gel consistency, gelatinization temperature, amylose along with glycemic index.In our study, significant variation was observed among all the varieties for chemical traits but no significant variation was observed in case of glycemic index.The amylose content observed over the varieties ranged from 21.7 per cent to 24.73 per cent. All the varieties have intermediate amylose content. Gel consistency ranged from 37.67 (hard gel) to 75 (soft gel) with the mean of 52.57. The alkali spreading value was noticed to be low, intermediate and high among all rice varieties.Glycemic index rangedfrom 56.72 -66.43 with a general mean of 60.67. Furthermore, all the varieties were categorized as medium GI varieties (56-69). Among all the varieties, Pushyami has shown the least value (56.72) for glycemic index.From the present investigation, it is concluded that, Rice varieties such as Chandra, Indra, Sri Dhruthi, Swarna, Samba Mahsuri, Sujatha, Maruteru Samba, MaruteruMahsuri recorded intermediate amylose, alkali spreading value and medium GI, which are desirable for rice consumers while counting for better rice with the best quality and glycemic index.
Development and evaluation of barnyard millet instant dosa mix
Authors: Karakannavar Sarojani , Nayak Geeta , Madhushri Y. , Hilli Jitendrakumar S.
Published: November 2021

Instant mixes offer great convenience to the homemakers to prepare traditional delicacies. It reduces the time and drudgery associated with the preparation. The present study aimed to at standardization of barnyard millet instant dosa mix. The impact of barnyard millet flour incorporation on sensory characteristics and shelf life of instant dosa mix was studied. Instant barnyard dosa mix with 50 per cent of barnyard millet flour was finalisedand assessed for shelf life. The particle size distribution of barnyard millet dosa mix and cooking characteristics of best accepted variation was carried out using standard procedures.The results revealed that, as millet flour increased, the thickness of dosa decreased and diameterwas increased, resulting in increased spread ratio.The nutrition composition of 100 g barnyard millet instant dosa mix contains9.50 % moisture, 12.67 % protein, 2.64 % fat, 1.81 % crude fibre,2.57 % ash, 72.62 %carbohydrates, 4.93 mg of iron, 2.21 mg of zinc and 23.94 mg of calcium. From storage study it is evident that the barnyard millet instant dosa mix stored in food grade aluminum foil pouches at ambient temperature can be stored for four and half months.
Effect of sulphur on growth, yield and economics of sesame (Sesamum indicum)
Authors: Sujatha V. , Saritha R. , Bhanu S.K. Haseena , Sirisha A.B.M. , Rao S.V.S. Gangadhara
Published: November 2021

The productivity of sesame is mainly dependant on proper agronomic management practices including nutrient management. In oilseeds, sulphur plays a prominent role in the synthesis of essential oils, chlorophyll formation and gives pungency in oil. It is also increasing drought and cold resistance of oilseed crops. Hence, field studies were conducted for two consecutive years to study the effect of various sources of sulphur (Gypsum and Sulphur Bentonite) and their different levels (15, 30 and 45 kg S ha-1) on growth, yield and economics of sesame. Studies revealed that, irrespective of sources of sulphur seed yield increased progressively with increase in sulphur dose from 15 to 45 kg ha-1 and the increase was significant at 45 kg ha-1 over 15 kg ha-1and control. Application of sulphur at 45 kg/ha through gypsum produced significantly higher plant height (97.1 cm), branches/plant (4.98), capsules/ plant (95.9) and seed yield (586.5 kg/ha) than at 15 kg S/ha through gypsum, Sulphur bentonite and recommended NPK and remaining at par with application of Sulphur at 30 kg/ha. Sulphur application at 45 and 30 kg ha-1 through gypsum recorded significantly higher net returns (Rs. 33365 and 31963 ha-1 respectively) and B: C ratio (2.47 and 2.38 respectively) than Sulphur Bentonite and recommended NPK during both the years.