bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Political Advertising on Voters Participation in Elections: A Study of 2019 General Election Participants in Anambra State
Authors: Ankeli Marjorie O.
Published: October 2023

The main objective of this study is to determine the effect of political advertising media on voters’ participation during election in Anambra State. The specific objectives are to: determine the effect of social media exposure, political rallies, mass media and town crier exposure on voter apathy, cynicism and political efficacy. Using a survey research design, a sample of 400 was selected randomly from the three senatorial districts in Anambra state. Questionnaire was used to collect the data. Data were presented using tables, percentages and frequencies while the study hypotheses were analyzed usim Structural Equation Model in Smart PLS software. Findings from the study show that: Town crier had a significant positive influence on voters’ participation; Political rallies had a significant positive effect on voters’ participation; Social media (Facebook) had a significant positive influence on voters’ participation; Mass media (Billboards) had a significant positive effect on voters’ participation. The study concludes that political campaign advertisement increasingly diversifying, more complex and demanding and its importance in political advertising is increasing. Therefore, the study recommends that: political advertising media such as town crier, political rallies, Facebook, and billboards are reliable tools which can be used by political parties and candidates during electioneering campaigns.
Artificial Intelligence and Computational Pathology: A comprehensive review of advancements and applications
Authors: Madoori Prashant Kumar , Sannidhi Sukumar , Anandam G
Published: October 2023

Abstract

Conventional pathology is essential for disease diagnosis, but challenges like inter-observer variability can impact treatment decisions. Immunohistochemistry assays improve patient identification, but advanced quantitative tools are needed for accurate marker quantification and spatial analysis. AI enhances accuracy in pathology by contextualizing spatial data and revolutionizing medicine through advanced data processing and machine learning. Clinical informatics and AI integration advance patient care and open new horizons in pathology. Artificial intelligence (AI) is crucial in pathology, leveraging deep learning techniques to integrate pathological images with radiological, clinical, and genomic data. These pattern recognition methods enhance disease diagnosis and prognosis assessment. This review article provides an overview of AI in pathology, recent advancements, and future prospects. It emphasizes digital pathology, image acquisition, data preprocessing, and feature extraction for AI-driven pathology analysis. A comprehensive analysis of the key findings and outcomes from recent studies incorporating AI in pathology is done. A focus on various applications, including but not limited to cancer diagnosis, grading, and prognosis, as well as the identification of specific tissue patterns and rare diseases. The impact of AI on workflow optimization, quality assurance, and predictive analytics in pathology is also discussed. This section explores the implications and challenges of AI adoption in pathology. We discuss benefits like enhanced accuracy and resource allocation but also cover limitations such as dataset requirements, ethics, interpretability, and regulations. Ongoing research and collaborations aim to address these concerns and ensure responsible AI implementation in pathology.
USG and CT-guided cytomorphological profile of FNAC in deep-seated lesions
Authors: Biswas Mridul Kanti , Saha Rajdeep , Ghosh Suman , Das Manas , Das Kausik
Published: October 2023

Abstract

Introduction: Ultrasound and computed tomography-guided fine needle aspiration cytology play an important role in the diagnosis of deep-seated lesions such as intra-abdominal and intrathoracic diseases.

Objective: To evaluate the efficacy of ultrasound (USG) and computed tomography (CT)-guided FNAC in the diagnosis of abdominal and intrathoracic lesions for one year, from January 2021 to December 2021.

Materials And Methods: The study included 58 intraabdominal and 45 intrathoracic lesions. Cytological findings were correlated to clinical and radiographic data to arrive at a definitive diagnosis.

Results: Fine needle aspiration cytology was performed at various anatomical sites: liver (24 patients), colon (9 patients), gallbladder (5 patients), ovary (6 cases), spleen (3 cases), mesentery (3 cases), omentum ( 3 cases), cecum (2 cases), pancreas (1 case), subhepatic lesions (1 case), lung (43 cases), mediastinum (2 cases). The most common intra-abdominal disease was metastatic adenocarcinoma of the liver (14 patients), and the most common intrathoracic disease was lung adenocarcinoma (18 patients).

Conclusion: Ultrasound and computed tomography-guided fine needle cytology is an excellent method for deep diagnosis in the abdominal and thoracic cavity.
Radiological study of foramen arcuale: implications for screw insertion via posterior arch for fixation of C1 vertebrae in atlantoaxial instability using plain radiograph
Authors: Hiroli Wasim , Gadade Varsha
Published: October 2023

Abstract

Introduction: Foramen arcuale is an osseous structure forming a bridge from the superior articular process of the atlas that completely or partially encircles the vertebral artery. We retrospectively reviewed plain cervical radiographs as suggested by neurosurgeons, neurologists and orthopaedic surgeons for evaluation of cervical spine problems. When foramen arcuale is present, it creates a false impression of a broad posterior arch and can pose a risk during neurosurgery. The aim of this study is to investigate the prevalence of foramen arcuale in the Jalgaon & Baramati population.

Materials and Methods: 1255 lateral cervical spine radiographs were obtained from the radiology department, GMC, Jalgaon & GMC Baramati. The patient of which 655 (59.04%) were males and 600(31.42%) were females. Cases were classified as an incomplete and complete bony ridge.

Results: Overall prevalence of Foramen arcuale was 8.36%, with complete lesions in 3.50% and incomplete lesions in 4.86%. We noted an increasing percentage of patients with Foramen arcuale from the younger to the adolescent age group, with significantly greater prevalence in patients aged 15-30 years compared with the younger groups. Lesions were more common in males (59.04%) compared with females (31.42%), but no statistically significant difference between genders was detected for complete as well as incomplete foramen arcuale (p=0.95).

Conclusion: The foramen arcuale is a relatively common osseous structural variant therefore; surgeons should consider the risk of the presence of an FA prior to procedures on the atlas in each patient. So we suggest the identification of this variant by preoperative lateral radiograph as a starting point for C1 lateral mass for screw fixation via the posterior arch for atlantoaxial instability. If foramen arcuale is suspected or confirmed on a radiograph, 3D CT scanning should be considered for variations in size and shape of foramen arcuale and the possibility of injury to the vertebral artery.
USO DA CÚRCUMA COMO ADJUVANTE NO TRATAMENTO DO DIABETES MELLITUS: UMA REVISÃO DA LITERATURA
Authors: Farias de Araujo Renata , Candido de Barros Wilibran , Silva Lima Emersom
Published: October 2023

O diabetes mellitus (DM) é um problema de saúde mundial que atingiu níveis alarmantes, onde quase meio bilhão de pessoas vivem com a doença atualmente. Diversos tratamentos são usados para o controle do DM, seja a monoterapia ou associações terapêuticas, dentre estes inclui-se o uso de antidiabéticos orais e fitoterápicos. Nesse contexto a cúrcuma surge como uma alternativa terapêutica   potencial como adjuvante no tratamento do DM. Com suas ações antioxidantes, anti-inflamatórias e hipoglicêmicas, a cúrcuma longa demonstra atividade não só no controle do diabetes mellitus tipo 2, mas também em suas complicações como a nefropatia diabética. A biodisponibilidade por via oral da cúrcuma enfrenta adversidades por conta da sua baixa absorção, distribuição tecidual limitada, meia-vida curta e rápida velocidade de biotransformação hepática, sendo este um fator limitante para aprovação clínica. O artigo faz uma revisão atual sobre os principais aspectos do uso da cúrcuma como adjuvante no tratamento do DM e conclui que esta planta apresenta propriedades benéficas aos pacientes diabéticos.
MEASURING THE IMPACT OF ECONOMIC STABILITY ON FINANCIAL SUSTAINABILITY IN IRAQ FOR THE PERIOD (2004-2020)
Authors: Abdullah Essa ALSALIM Rajaa
Published: October 2023

The research discussed the impact of economic stability on financial sustainability in Iraq, and annual data was adopted for indicators of economic stability as an independent variable and indicators of financial sustainability as a dependent variable for the period (2004-2020)). On the stability of the time series of the research variables at the level, except for the growth rate of the budget deficit, it settled at the first difference, between the research a direct relationship between the growth of GDP and the ratio of public debt to GDP through the cointegration test and the existence of a long-term equilibrium relationship in addition to the adoption of the ARDL approach To measure the effect of economic stability on the growth rate of the general budget deficit, the research shows that the direct relationship between economic stability and the growth rate of the public budget deficit is a long-term equilibrium relationship, and that the models estimated by standard methods are distributed normal, and that errors are stable and free from the problem of autocorrelation and the problem of heterogeneity
The Effect of Motivation for Social Participation in the Elderly on Depression: Moderating Effect of Social Capital
Authors:   The K Association of Education Research, Choi Go-Woon , Kim Jun-Su
Published: October 2023

The purpose of this study is to examine and verify whether social capital modulates the relationship between motivation for social participation and depression in the elderly. To this end, data were collected through a questionnaire survey targeting elderly people aged 65 or older in the Jeonbuk area, and responses were collected from 414 people. Among them, the response data from 395 people were analyzed by a controlled regression equation using the SPSS 25.0 statistical program, and a simple slope test was performed. . The analysis results are as follows. First, as the relationship-oriented motivation among the elderly's social participation motivation increased, the elderly's depression decreased. Second, as social capital increased, depression in the elderly decreased. Third, as a result of verifying the moderating effect of social capital in the relationship where the elderly's social participation motivation (self-oriented motivation, relationship-oriented motivation, social-oriented motivation) affects depression in the elderly, the group with high social capital is the group with low social capital. In comparison, social participation motives (self-oriented motives, relationship-oriented motives) had a greater influence on depression in the elderly. Based on this, it was confirmed that social capital modulates the effect of the elderly's social participation motivation (self-oriented motivation, relationship-oriented motivation) on depression in the elderly. Based on these results, practical and policy suggestions were made on ways to provide social participation opportunities for the improvement of depression in the elderly, ways to form a social support network, and social participation activities for the elderly that can be applied at the community level.
The Relationship Between Digital Literacy, Social Capital, and Self-Efficacy using Digital Devices of the Elderly
Authors:   The K Association of Education Research, Lee Ju-Eun , Kim Jun-Su
Published: October 2023

The purpose of this study is to analyze the effect of the elderly's digital literacy on the formation of social capital and to verify the mediating effect of the elderly's digital device use self-efficacy in this relationship. To this end, the digital information gap fact-finding data conducted in 2022 was used as an SPSS 25.0 statistical program to determine the relationship between demographic characteristics, digital literacy, and self-efficacy using digital devices as independent variables and the social capital of the elderly as a dependent variable. analyzed. As a result, it was found that social capital also increased when the independent variable, digital literacy, was improved. In addition, it was analyzed that social capital increased as the self-efficacy of using digital devices in the elderly increased. Subsequently, as a result of analyzing the mediating effect of digital device use self-efficacy in the relationship between digital literacy and social capital of the elderly, digital literacy had a positive effect on social capital, and the path mediated by digital device self-efficacy was also statistically significant. Significant results were obtained. Based on the results of this study, practical efforts such as conversion of educational contents that can be used in daily life from simple contents-oriented education of educational institutions to improve the digital literacy of the elderly are suggested.
A Study on Interpersonal Problems in College Students
Authors:   The K Association of Education Research, Jeong Seong-Ran
Published: October 2023

The purpose of this study was to present basic data to prevent dropout by investigating and analyzing the characteristics of interpersonal problems related to maladjustment or dropout of college freshmen. To achieve this goal, 405 freshmen from K University in Daegu(117 males·288 females, 138 natural science majors·144 humanities and social science majors·123 artistic and physical education majors) were tested for interpersonal problems. The results were analyzed. The measurement tool is the Korean Inventory of Interpersonal Problem(KIIP), a self-report test with 99 questions. For data analysis, descriptive statistics, frequency analysis, and correlation analysis were conducted using the SPSS program. As a result of this study, it was found that the area of social inhibition was the highest in interpersonal problems, and the average of interpersonal problems was the highest among students in the humanities, social sciences and arts and physical education. All of the highest areas on the personality disorder scale were lack of sociability. In the personality disorder scale, interpersonal hypersensitivity and interpersonal non-acceptance were the subscale that had the highest correlation with the overall score. After analyzing the correlation between the entire interpersonal problem scale and the personality disorder scale, it was found that egocentrism had the highest correlation. In conclusion, since college freshmen have difficulties such as social inhibition, non-assertiveness, hyper-conformity, and deficiency of sociability, it seems that various programs are needed to help them.
Big Data Analysis Research on Private Investigation Systems
Authors:   The K Association of Education Research, Cho Cheol-kyu
Published: October 2023

In this study, we would like to explore how the media means the private investigation system through “Big Cains,” a news big data analysis site. Therefore, it provided a big data system for the media and collected data from various media organizations to analyze media reports on private investigations through BigKinds, a news big data analysis system created as news content. In order to achieve the purpose of the research, the flow of keywords was identified by dividing them into 2000s, 2010s and 2020s and deriving and presenting the number of related articles every year during that period. As a result of this study, it was found that in the 2000s, the frequency of media reporting was low at a time when public interest in the private investigation system and various studies were not conducted in academia. Second, in the 2010s, there was a high topic rank on the private survey system compared to the 2000s, and various research and education were conducted in academia and industry related to government policies and private surveys. Third, the 2020s marked a high topic rank as related laws were revised, heralding a new change in the private investigation system. Therefore, it is hoped that the government will move in a direction that will greatly help the people's security demand by supplementing the protection of citizens' rights, minimizing conflicts between direct translations, and limitations of national security.
A critical discourse analysis of social and structural inequalities that exist between NET and NNETs in South Korea's English Hiring Market
Authors:   The K Association of Education Research, Lee Young Eun
Published: October 2023

English has become a crucial aspect of South Koreans' lives, and there exists a transnational linguistic market where English is a highly prized commodity. Private and public academic institutions, as well as national English programs, make significant financial investments to find Native-speaking English Teachers (NETs) to work in South Korea. Previous studies have revealed employment decisions for EFL teachers in Asia are frequently influenced by a candidate's “nativeness” as opposed to their professional accomplishments, such as their teaching experience and academic credentials. The NETNNET dichotomy in the EFL area is very problematic as it fosters discriminatory practices, yet little is known is known how these tensions play out in the South Korean context. By employing Norman Fairclough’s three-dimensional CDA framework, this paper seeks to critically examine the discourses surrounding the native and non-native English language teachers are constructed in the Korean English market. This paper identifies how relations of inequalities, power, and domination are reproduced or produced in discourse. Data include analysis of the texts in hiring advertisements for English language teachers in South Korea. Through CDA, I sought to reveal and confront dominant ideologies and discourses reflected in the texts. This paper concludes with suggestions on how to challenge the inequitable practices and policies widely present in the South Korean English market.
The High School Student Study Pre-parents’ Perceptions About Childcare Education of Infants and Toddlers
Authors:   The K Association of Education Research, Park Eun-Ju
Published: October 2023

The purpose of this study was to investigate the perception of parents of prospective high school students on the education of their children in early childhood. The subjects of the study were 245 high school students enrolled in G Metropolitan High School. The research questionnaire consisted of the number of children expected, the gender of the desired child, the reason why the child is needed, the desired form of education for infants and toddlers, the most important points when educating infants and toddlers, the education that should be given the most priority to infants and toddlers, the best way to educate infants and toddlers about basic lifestyle habits and personality, the cost of education for infants and toddlers for one month, the future hope that our child will become the most, and the most influential for infants and toddlers to grow. As a result of the analysis using SPSS 23.0, the respondents showed a tendency to expect two children and want them regardless of gender, and emphasized bonding and a sense of creation and achievement as reasons for needing children. The desired form of education for children in early childhood appeared to be parents, and character education was considered the most important. In addition, personality education and basic lifestyle habits were shown to be the education that should be given the highest priority, and the opinion that it should be carried out naturally at home was emphasized. The monthly cost of children's education was less than 50 to 1 million won, and the children's future hopes were mainly what the children wanted, and the parents' education and upbringing methods had a great influence on the growth of children. This study will be used as an important basic data for the education of infants and toddlers in Korea.
Os acordos de não persecução cível na seara da improbidade administrativa: impactos trazidos pela Lei 14.230/2021
Authors: Tourinho Rita
Published: October 2023

O artigo tem a finalidade de abordar os impactos ao instituto do Acordo de Não Persecução Cível no âmbito da Improbidade Administrativa devido a publicação da Lei 14.230/2021, norma que alterou a Lei de Improbidade Administrativa (Lei 8.429/1992). Desenvolve voltando-se para Direito Administrativo Sancionador e abordando a consensualidade de modo sistemático descrevendo os ajustes nos casos de improbidade administrativa até o acolhimento. Desse modo, promove metodicamente a análise da natureza, dos requisitos e do alcance do Acordo de Não Persecução Civil. Pontua as principais alterações na Lei de Improbidade Administrativa promovidas na publicação da nova regra. Aponta a possível repercussão aos Acordos de Não Persecução Cível que se encontram formalizados mediante a questão da retroatividade da atual normativa. Pondera na conclusão a alteração causou um impacto direito aos objetos de acordos, tal fato exclui um grande número de condutas que anteriormente estavam tipificadas como ato de improbidade.
Surface Characterization, Mechanical Properties, and Corrosion Behavior of Zn-Ni Alloy Coated Steel Using Electroplating-Hot-Dip Galvanizing
Authors: Raghebi Zahra , Parvini Ahmadi Nagi , Khosroshahi Rasul Azari , Jafari Robabeh
Published: October 2023

In this study, the processing of zinc-nickel alloys with an electroplated nickel layer as the first layer followed by hot-dip galvanizing on plain carbon steel (St37) is investigated. The effect of the nickel layer and the effect of the immersion time on the alloy layers of the coating obtained by this method are studied. In addition, some properties of the obtained coating, such as the overall thickness, hardness, surface uniformity, coating adhesion strength, and corrosion resistance, were investigated using the optical microscope, scanning electron microscopy, energy dispersive x-ray spectrometer analysis, and potentiostat. The results show that the 16-min immersion time is the optimum galvanizing time at which an alloy with a nickel content of 0.11 wt% is formed and that the overall thickness of the galvanized sheet, especially the alloy layers, decreases compared to the pure zinc sheet. In addition, a more ductile, corrosion-resistant, and smoother surface is obtained.
European students are more likely to provide incorrect HIV testing indications as compared to other international students
Authors: Kowalska Justyna D. , Kozioł-Kaczorek Dorota , Horban Andrzej
Published: October 2023

Introduction:  Expanding HIV testing is recognised as a major tool in halting the HIV epidemic. However, HIV testing is still advised inadequately by medical practitioners. Therefore we investigated medical students’ knowledge on HIV and indications for HIV testing.

Material and methods: Fifth year students were pre-tested while entering the infectious diseases course. Questionnaires were anonymous and covered three areas: medical practice, transmission risk and indications for HIV testing. Logistic regression models were used to identify factors associated with incorrect responses to questions on HIV testing indications.

Results: In total 224 students were included; 64% were female. The majority of students were from Europe (64.3%), followed by Asia (24.5%), North Africa (6.3%) and North America (4.9%); 72.8% were from high-income countries. Only 91 (41%) students provided correct indications for HIV testing, i.e. including sexual contacts, STDs or pregnancy in addition to medical condition. Over half (54%) listed only medical conditions related to immunodeficiency as an indication for HIV testing. In the multivariate logistic regression model the odds of incorrect indications for HIV testing were higher for European students (odds ratio (OR) = 2.56, 95% CI: 1.19–5.50; p < 0.016) and those overestimating the homosexual risk of HIV infection (OR = 1.03, 95% CI: 1.00–1.06; p = 0.026). The odds were lower for students overestimating the risk of mother-to-child transmission (OR = 0.97, 95% CI: 0.96–0.98; p < 0.001).

Conclusions: Students tend to represent a condition-focused HIV testing approach, underscoring the importance of behaviour-related indications, as well as the asymptomatic character of HIV infection. This observation is especially relevant for students originating from Europe.
Effects of prognostic factors on overall and disease-free survival in patients with stage I–III colorectal cancer
Authors: Çetin Durmuş Ali , Yildirim Mehmet , Yakan Savaş , Çiyiltepe Hüseyin , Aydoğan Serdar
Published: October 2023

Introduction: The aim of this study was to retrospectively analyze predictive factors for overall survival (OS) and disease-free survival (DFS) rates in patients with stage I, II, or III colorectal cancer who underwent surgical treatment.

Material and methods: Files and electronic data of 120 patients with stage I, II, or III colorectal cancer who underwent surgery between 2008 and 2012 in the Department of General Surgery of Izmir Bozyaka Research and Training Hospital were retrospectively analyzed. The effects of several prognostic factors for DFS and OS were investigated.

Results:  There were 45 (37.5%) female and 75 (62.5%) male patients; mean age was 65.51 ±11.29 years. In univariate analysis, length of DFS was found to be associated with presence of perforation, lymphovascular invasion, preoperative carcinoembryonic antigen (CEA) value and positive surgical margin. Presence of comorbidities, American Society of Anesthesiologists (ASA) score, histological grade of tumor, presence of lymphovascular invasion, preoperative CEA value, preoperative albumin value, number of metastatic lymph nodes and positive surgical margin were found to be independent prognostic factors for DFS. Cox regression analysis indicated radial surgical margin and presence of perforation had statistical significance for DFS (p value of 0.008 and 0.025, respectively).

Conclusions: There are numerous prognostic parameters affecting postoperative survival in colorectal cancers. Prospective studies and studies on a larger scale are necessary in order to more accurately designate clinical prognostic factors that have an effect on survival time and to identify new biological and molecular markers.
3D CT scan assessment of the outcome of displaced intra-articular calcaneal fractures: operative versus non-operative treatment
Authors: Bajuri Mohd Yazid , Veerakumaran Rajkumar , Ali Abdul Muhaimin , Sridharan Radhika , Rehir Rasyidah
Published: October 2023

Introduction

Computed tomography (CT) scan is helpful in identifying bone deformities resulting from intraarticular calcaneal fractures such as loss of calcaneal height, increased width of calcaneal wall, and disruption of the posterior articular facet. The aim of this study is to compare the result of spiral CT scan assisted analysis of calcaneum anatomy, articular congruity and onset of arthritic changes with intraarticular calcaneal fractures in patients treated either operatively or conservatively.

Material and methods

Twenty patients were recruited, 9 in the operative group and 11 in the conservative group. CT scan of the injured foot and ankle were taken followed by detailed functional assessment based on the American Orthopaedic Foot & Ankle Society Score (AOFAS) and Maryland Foot Score (MFS). Calcaneal height, length and width were measured to assess the functional and radiological outcome in the patients. The presence and severity of arthritic changes were reviewed.

Results

The calcaneal height, length and width were relatively restored in the operative group compared to the conservative group. A significantly larger posterior articular facet step was seen in the conservative group with accelerated onset and significantly higher (p = 0.001) grade of arthritis in the subtalar joints apart from having significantly higher (p = 0.038) incidences of calcaneocuboid arthritis. The operative group showed significant improvement (p = 0.009) in functional outcome based on MFS scoring system.

Conclusions

Operative intervention with calcaneal locking plate provides good framework for near anatomical bone healing and redistributes the mechanical forces on the foot resulting in improved pain, function and alignment in patients.
Comparison of Mortality in Patients with Multiple Morbidities and with Single Morbidity Admitted at Acute Medical Unit, Pak Emirates Military Hospital, Rawalpindi, Pakistan
Authors: Sharif Nazia , Fazal Imran , Noor Ul Ain
Published: October 2023

Objective: to discover the impact of single and multimorbidity on the specific outcomes in patients admitted to a critical care setup, Acute Medical Unit, at Pak Emirates Military Hospital, Rawalpindi Pakistan.
Study Design: Cross sectional comparative study.
Place and Duration of Study: Acute Medical Unit, Pakistan Emirates Military Hospital, Rawalpindi Pakistan, from Aug 2018
to Jan 2019.
Methodology: All patients admitted to AMU were included in the study. Age was kept as the primary inclusion criteria for
this study. Non-probability convenient sampling technique was used. After exclusion, the final sample size was 354. Data was analysed using SPSS version 22.0.
Results: Out of 354 patients that were included in the study, 215(60.7%) were males while 139(39.3%) were females. The
patients were divided in 4 age groups i.e., 15-35 years, 36-55 years, 56-75 years and 76-90 years. Based on the history taken from the patient and the lab tests ordered, 216(61%) had more than one disease while 138(39%) had only a single disease. Most common comorbid diseases, found in our study were diabetes mellitus, hypertension, ischemic heart disease (IHD) and cerebrovascular accident, Mortality rates of patients with multiple morbidities were higher than those with single morbidity.
 
Conclusion: Multimorbidity is a great challenge faced by physicians of today. Our study found greater mortality rates in patients with multiple morbidities and greater age than those with single morbidities and lesser age.
Correlation of Percentage of Ki67 with Tumor Grade in Breast Cancer
Authors: Khan Aveen Yousuf , Haider Ghulam , Zahoor Saima , Nouman Maryum , Bukhari Neelma
Published: October 2023

Objective: To determine the association of Ki67 with tumor grade and other pathological features in patients with breast carcinoma.
Study Design: Cross-sectional analytical study.
Place and Duration of Study: Department of Medical Oncology of Jinnah Postgraduate Medical Center, Karachi Pakistan, from Jul 2018 to Jul 2019
Methodology: Two hundred and sixty females diagnosed with breast carcinoma of age more than 19 years were included using non-probability consecutive sampling technique. The histologic grade of tumor has been assessed using the classification of the World health organization. Representative sample was selected from each tumor for immune histochemical staining examination including estrogen receptors, progesterone receptors, Her2neu and Ki67. Nuclear expression has been quantitatively documented for Ki67.
Results: The mean age of the study sample was noted as 46.93±12.8 years ranging from 20 to 76 years. Of 260 patients, 17 patients (6.5%) had low Ki67 (1-5%), 23 patients (8.8%) had intermediate Ki67 (6-14%) and 220 patients (84.6%) had high Ki67 (≥15%). The significant relationship was found between Ki67 status and age, stage, tumor size, grade, lymph node status, estrogen receptors, progesterone receptors, HER2/Neu and triple negative (p<0.05).
Conclusion: Ki67 index is associated with tumor grade and other pathological features such as stage, tumor size, lymph node status, estrogen receptors, progesterone receptors, HER2/Neu and triple negative.
Role of Percutaneous Bone Marrow Aspirate in the Management of Femoral Delayed Union and Non Union Fractures
Authors: Muhammad Rehan Saleem  , Rana Shahbaz Ahmad  , Shahzad Inam  , Shahzad Inam  , Adnan Anwer  , Osma Jafar  , Hassan ud Din Hassan
Published: October 2023

Objective: The objective of the study is to radiologically ascertain bone union following percutaneous autologous bone marrow aspirate injection in the management of delayed union and non-union fractures of femur.
Study design: Case series.
Duration and place of Study: Department of Orthopedics, Combined Military Hospital, Rawalpindi Pakistan, from Jan to Jun 2019.
Methodology: Forty-two (42) patients of fracture femur who fulfilled the inclusion criteria were enrolled in the study. Fresh radiographs of affected side were performed to document cases of delayed union and nonunion. 50ml of bone marrow aspirate from iliac crest was injected at fracture site. Results were evaluated after 12 weeks with the help of radiographs to see radiological union of bone.
Results: A total of 42 patients were included in the study. 37(88.09%) were males and 5(11.9%) were females between the ages of 18 and 60 years. The mean age of patients was calculated to be 34.80±11.17 years. Radiological union was achieved in 32(76.19%) patients.
Conclusion: Radiological assessment shows percutaneous injection of bone marrow as a safe procedure with bone healing in 12 weeks in patients with non-union or delayed union.
The effects of Equal Weight Bearing Sit-to-Stand Exercise Program on Balance in Stroke Patients: A Randomized Clinical Trial
Authors: Iqbal Muhammad Hussain , Khalid Fariha , Ahmad Ashfaq , Shahid Sana , Iqbal Zarmeen
Published: October 2023

Objective: To determine the effectiveness of routine physical therapy with and without equal weight bearing sit to standexercise program on balance in stroke patients.
Study Design: Randomized Clinical trial (IRCT-50122)
Place and Duration of Study: Physiotherapy department of University of Lahore Teaching Hospital, Omer Medical Centre,Lahore and Yaseen Medical Centre, Lahore Pakistan from Nov 2019 to Jun 2020.
Methodology: The 24 participants with sub-acute stroke aged 40-60 years were divided randomly using lottery method, into two equal groups of 12 each. A random number table was generated using computer. All random numbers were kept in a sealed envelope. For each patient a sealed envelope was opened and according to mentioned number, group was allocated. The assessment was done before treatment, at 4th week and after 8th week of intervention. Control Group received the 3 sessions per week of routine physical therapy treatment. Experimental Group received 3 sessions per week of routine physical therapy with equal weight bearing sit-to-stand exercise.
Results: Control Group consist of 12 stroke patients, out of which had 5(41.7%) hemorrhagic while 7(58.3%) had ischemic stroke. In Experimental Group, there were 2(16.7%) hemorrhagic while 10(83.3%) stroke patients. According to p-value=0.001 for factor significant improvement was seen in berg balance scale total score from baseline till 2nd follow up.
Conclusion: This study concluded that equal weight bearing sit to stand exercise program with routine physiotherapy was aneffective treatment to improve balance in sub-acute stroke patients as compared to the only routine physiotherapy.
EGFR-TKI Sensitizing Mutation Rate in Adenocarcinoma of Lung
Authors: Sana Sehar  , Ghulam Haider  , Berkha Rani  , Versha Rai  , Tooba Ather  , Batool Memon
Published: October 2023

Objective: To assess EGFR-TKI sensitizing mutation rate in patients having lung adenocarcinoma and its association with smoking status.
Study Design: Cross-sectional study.
Place and Duration of Study: Department of Medical Oncology, Jinnah Postgraduate Medical Center, Karachi Pakistan from Apr to Dec 2019.
Methodology: One eighty-seven patients aged 20-75 years, of either gender presented with confirmed diagnosis of adenocarcinoma of lung were included in the study. The data regarding characteristics of patients such as gender, age, smoking status, ethnicity and religion were recorded on pre-designed proforma. The examination of EGFR mutation in plasma and tissue specimens was done by the Real-Time polymerase chain reaction assays. SPSS version 23 was used to analyze data.
Results: Out of 187, 65(34.8%) patients presented with EGFR TKI-sensitizing mutation and among them 48(73.8%) patients had exon 19 deletion and 17(26.2%) patients had exon 21 L858R point mutation. In patients with positive EGFR, 90.8% were never smokers and 9.2% were smokers or ever smokers. The statistically significant relationship was found between EGFR mutation and smoking status (p=0.001).
Conclusion: This study showed EGFR-TKI mutation frequency as 34.8% which in contrast to western studies where EGFR mutation is less frequent. Further, never smokers are at greater risk of EGFR mutation.
Pengaruh Jalur Pelaporan Anonim Terhadap Niat Whistleblowing Dengan Moderasi Religiusitas
Authors: Lakaba Rosalyn , Pesudo David Adechandra Ashedica
Published: October 2023

Whistleblowing merupakan pengungkapan kecurangan individu atau organisasi yang dilakukan oleh anggota organisasi terkait prakitk-praktik kecurangan dalam organisasi. Whistleblowing dianggap sebagai salah satu cara efektif dalam pencegahan dan pendeteksian kecurangan. Penelitian ini bertujuan untuk menguji pengaruh jalur pelaporan anonim terhadap niat whistleblowing dengan mengunakan religiusitas sebagai variabel moderasi. Penelitian ini juga menggunakan sampel dari universitas swasta berbasis agama yang berada di Salatiga dan universitas negeri tidak berbasis agama yang berada di Makassar karena penulis ingin mengetahui apakah ada perbedaan atau tidak. Hasil penelitian menunjukkan bahwa pada universitas berbasis agama niat seseorang untuk melakukan whistleblowing dipengaruhi oleh jalur pelaporan anonim. Tetapi sebaliknya, pada universitas tidak berbasis agama jalur pelaporan anonim tidak menjadi pengaruh pada niat whistleblowing. Namun, berbeda dengan prediksi, penelitian ini menemukan bahwa religiusitas tidak dapat memoderasi jalur pelaporan anonim terhadap niat whistleblowing baik itu pada universitas berbasis agama maupun tidak berbasis agama.
DETERMINASI HARGA SAHAM PERUSAHAAN JASA SUBSEKTOR PROPERTY DAN REAL ESTATE
Authors: Ihza A Nur Kholifah , Meirini Dianita
Published: October 2023

Investor yang ingin berinvestasi sepantasnya berhati-hati dan mencari tanda-tanda bahwa perusahaan sedang mengalami masalah keuangan atau dalam kondisi baik. Oleh karena itu, diperlukan kajian keuangan atas laporan keuangan perusahaan, serta pemeriksaan rasio-rasio keuangannya. Penelitian ini bertujuan menganalisis pengaruh Working Capital Turn Over, Debt To Equity Ratio dan Pertumbuhan Aset Terhadap Harga Saham perusahaan jasa dalam subsektor property dan real estate yang terdaftar di Bursa Efek Indonesia. Metode pengambilan sampel menggunakan purposive sampling, sehingga didapatkan total jumlah 34 perusahaan pada sampel penelitian. Metode analisis data menggunakan analisis regresi linier berganda yang diolah menggunakan aplikasi SPSS 25. Hasil penelitian uji simultan menunjukkan bahwa working capital turn over, Debt To Equity Ratio dan pertumbuhan aset berpengaruh signifikan terhadap harga saham. Uji parsial menunjukan bahwa working capital turn over berpengaruh signifikan terhadap harga saham, debt to equity ratio tidak berpengaruh signifikan terhadap harga saham dan pertumbuhan aset berpengaruh signifikan terhadap harga saham.
Pengaruh Profitabilitas, Ukuran Perusahaan, Kebijakan Dividen dan Keputusan Investasi Terhadap Nilai Perusahaan
Authors: Dita Fernanda Vio , Ratna Dwiati Agustina
Published: October 2023

Abstrak. Pengaruh Profitabilitas, Ukuran Perusahaan, Kebijakan Dividen dan Keputusan Investasi Terhadap Nilai Perusahaan.  Tujuan dilakukannya penelitian ini adalah untuk menguji apakah profitabilitas, ukuran perusahaan, kebijakan dividen dan keputusan investasi mempengaruhi nilai perusahaan. Nilai perusahaan menggambarkan kepercayaan pasar atas kinerja perusahaan dan dapat tercermin melalui harga saham. Penelitian ini menggunakan nilai perusahaan sebagai variabel dependen sedangkan variabel independen yang digunakan adalah profitabilitas, ukuran perusahaan, kebijakan dividen dan keputusan investasi. Penelitian ini bersifat kuantitatif dengan menggunakan data sekunder. Populasi penelitian yang digunakan adalah perusahaan manufaktur yang telah terdaftar di Bursa Efek Indonesia pada tahun 2016-2018. Penentuan sampel menggunakan metode purposive sampling. Total data yang digunakan sebanyak 146 data. Metode penelitian adalah analisis regresi berganda dengan menggunakan SPSS. Hasil dari penelitian ini menunjukkan bahwa profitabilitas, ukuran perusahaan dan keputusan investasi mempengaruhi nilai perusahaan. Semakin tinggi nilai profitabilitas, ukuran perusahaan dan keputusan investasi akan meningkatkan nilai perusahaan. Sementara itu, kebijakan dividen tidak mempengaruhi nilai perusahaan.

Kata Kunci: Kebijakan Dividen, Keputusan Investasi, Nilai Perusahaan, Profitabilitas, Ukuran Perusahaan.
COTS PINE (PINUS SYLVESTRIS L.) PERSPECTIVENESS DETERMINATION TO CREATE THE CARBON FORMS
Authors: Котова В.С. , Корчагин И.Е. , Розинкина Е.П. , Петров А.И. , Осипенко Р.А. , Годовалов Г.А.
Published: October 2023

По показателю значений флуктуирующей асимметрии хвои подроста сосны обыкновенной (Pinus sylvestris L.) предпринята попытка определения перспективности использования данной породылесообразователя для создания карбоновых ферм на нарушенных землях. Объектом исследований служил подрост сосны обыкновенной, произрастающий на выработанной части Исетского гранитного карьера и на прилегающих территориях. Район проведения исследований относится к Средне-Уральскому таежному лесному району. У экземпляров подроста отбирались образцы парных хвоинок 2022 и 2021 гг. У каждой пары в лабораторных условиях замерялась длина хвоинок с целью установления показателя флуктуирующей асимметрии. Сравнение полученных показателей у подроста, произрастающего на выработанной части карьера и на опушке леса, показало отсутствие статистически достоверных различий в показателях флуктуирующей асимметрии. Таким образом, на бедном питательными элементами субстрате выработанного гранитного карьера сосна обыкновенная прекрасно себя чувствует и не испытывает стрессового состояния. Последнее позволяет рекомендовать сосну обыкновенную в качестве главной древесной породы при создании карбоновых ферм на нарушенных землях. Главным при выборе сосны является тот факт, что она хорошо растет даже на субстратах, бедных питательными веществами.

In terms of the ﬂ uctuating asymmetry value of scots pine undergrowth needess (Pinus sylvestris L.) an attempt was made to determine the prospets to use this type of forest former for creating carbon forms on disturbed lands. The object of research was the scots pine undergrowth growing on the developed part of the iset granite quarry and on the adjacent territories. The study area belongs to the middle Ural taiga forest region. From specimens of undergrowth, samples of paired needess of 2022 and 2021 years, were taken. For lach pair in laboratory conditions it was measured the length of the needles in order to determine the ﬂ uctuating asymmetry indicator. Comparison of indicators of undergrowth growing on the developed part of the quarry and on the edge of the forest showed the absence of statistically signiﬁ cant differences in ﬂ uctuating asymmetry indicators. Thus, on a nutrient-poor substarate of a worked out granite quarry. Scots pine ﬂ eels perfectly well and does not experience a stressful state. The latter maxed it possible to recommend scots pine as a main tree species in the creation of carbon farms on disturbed lands when choosing pine, the main fact is fact that it grows well even on substrates poor in nutrients.
CRITERIA FOR SELECTION OF STANDS FOR EXPERIMENTAL CUTTINGS
Authors: Годовалов Г.А. , Залесов С.В. , Сураев П.Н. , Мишкина И.А.
Published: October 2023

На примере Уральского учебно-опытного лесхоза (УУОЛ) Уральского государственного лесотехнического университета (УГЛТУ) предпринята попытка анализа лесного фонда по группам типов леса и лесным формациям. Выполненная работа позволяет объективно оценить лесорастительные условия УГЛТУ, интенсивность смены пород и наличие коренных и производных типов леса, а также возрастную структуру древостоев. Работа выполнена с использованием ГИС-технологий и банка данных лесоустроительных материалов. Полученные данные позволят на научной основе подобрать участки для создания научных и опытно-производственных объектов по изучению лесоводственной эффективности различных видов рубок спелых и перестойных насаждений, а также рубок ухода. Анализ полученных данных не только сократит расходы на создание опытных объектов, но и будет способствовать совершенствованию противопожарного устройства, а также повышению продуктивности лесов. Последнее особенно важно, если учесть, что УУОЛ УГЛТУ является базовым подразделением, нацеленным на совершенствование подготовки высококвалифицированных специалистов для лесного комплекса.

On the example of the Ural educational and experimental forestry (URSF) of the Ural state forest engineering university on aftempt was made to analyze the forest fund by groups of forest types and forest formations. The work performed makes it possible to objectively assess the forest conditions of the university the intensity of breed change, the presence of indigenous and derived forest types as the age structure of forest stands. The work was carried out ising GIS-technologies and data bank of forest management materials. The data obtained will allow on a scientiﬁ c basis to select sites for the creation of scientiﬁ c and experimentally production objects for forestry effectiveness studying of various types of cuttings in mature in mature and overmature stands as well as for thinning. The analysis of the data obtained will not only reduce the cost of creating experimental facilities, but will also improve the ﬁ re-ﬁ ghting device, as well as increasing the productivity of forests. The latter is especially important considering that UEET of the USFEU is a basic subavision aimed at improving the training of highly qualiﬁ ed specialists for the forest complex.