bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of the CB1 receptor antagonists AM6545 and AM4113 on metabolic syndrome-induced prostatic hyperplasia in rats
Authors: Eid Basma G. , Neamatallah Thikryat , Binmahfouz Lenah S. , Bagher Amina M. , Alamoudi Abdulmohsin J. , Aldawsari Hibah Mubarak , Hanafy Abeer , Hasan Atif , El-Bassossy Hany M. , Abdel-Naim Ashraf B. , Vemuri Kiran , Makriyannis Alexandros
Published: May 2023

Metabolic syndrome (MetS) is a combination of metabolic disorders that can predispose individuals to benign prostatic hyperplasia (BPH). The inhibition of the cannabinoid 1 (CB1) receptor has been used to treat metabolic disorders in animal models. This study reports the use of a peripherally restricted CB1 antagonist (AM6545) and a neutral CB1 antagonist (AM4113) to improve MetS-related BPH in rats. Animals were divided into three control groups to receive either a normal rodent diet, AM6545, or AM4113. MetS was induced in the fourth, fifth, and sixth groups using a concentrated fructose solution and high-salt diet delivered as food pellets for eight weeks. The fifth and sixth groups were further given AM6545 or AM4113 for additional four weeks. Body and prostate weights were measured and prostate sections were stained with haematoxylin eosin. Cyclin D1, markers of oxidative stress and inflammation, and levels of the endocannabinoids were recorded. BPH in rats with MetS was confirmed through increased prostate weight and index, as well as histopathology. Treatment with either AM6545 or AM4113 significantly decreased prostate weight, improved prostate histology, and reduced cyclin D1 expression compared with the MetS group. Groups treated with CB1 antagonists experienced reduced lipid peroxidation, recovered glutathione depletion, restored catalase activity, and had lower inflammatory markers interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-α). MetS rats treated with either AM6545 or AM4113 showed reduced concentrations of anandamide (AEA) and 2-arachidonoylglycerol (2-AG) in the prostate compared with the MetS group. In conclusion, the CB1 antagonists AM6545 and AM4113 protect against MetS-induced BPH through their anti-proliferative, antioxidant, and anti-inflammatory effects.
REPRESENTATION OF TOPOGRAPHY AS A DESIGN INSTRUMENT: EXPERIENCE IN A DESIGN STUDIO
Authors: KORUR Zülal Nurdan
Published: May 2023

Aim: Based on the argument that the abstract representation of topography makes new design possibilities visible it is aimed to evaluate the design processes of students within the scope of design studio. The scope of the study was determined as the analysis of the topographic structure of the place through instrumentalization. This study was determined within the framework of making the possibilities of representation visible in the architectural design process and observing the interaction of students with these representational levels. The design period is limited to the fourteen-week period of architectural education. A defined design problem given to the students forms the upper frame of the studio. Method: The method of this research was created by recording the ideas, discussions and criticisms of the students on a design problem of the learning processes that took place in the architectural design studio. Results: Making a topography model with a different method than usual changes the student’s perspective on design. Conclusion: It has been observed that starting the first-year architectural design studio education with a tool that the student can use in the design process carries the acquisition of design skills to an advanced level.
QUANTITATIVE ASSESSMENT OF TELEVISION SERIES SOURCED INTENTIONAL DAMAGES: AYVANSARAY-BALAT
Authors: ULAŞ SARIAYDIN Ebru , HALAÇ Hicran Hanım , KÖSE Hasan Hüseyin
Published: May 2023

Aim: The question of how the directions in film and TV series editing will affect the shooting areas has been dealt with in the scale of graffiti in the study, and it is aimed to prove the reflection on the set area. In the study, which was prepared to create attention for the shootings on historical places, the Çukur Series published between 2017-2021 and the historical Balat and Ayvansaray streets and structures where the shootings were made were examined. Method: Within the boundaries of the scenario, 113 structures, including their registered structures, were examined. The analysis, which was designed to prove the amount of intervention caused by the series, was documented with the number of buildings with graffiti on their façades, their registration status, the increase in interventions, the vandalism valuation method designed within the scope of the study, and the percentage calculations of the area occupied by the interventions on the facades. Findings: With the series, the identity of the Pit, which dominates the historical identity in the set area, has been reached day by day. While the number of facades with graffiti was 15 in 2017, Pit content was found in 88% of the facades that increased to 61 in 2019, and in 82% of the facades that reached 72 in 2020. Conclusion: The need for control and limitation for the fictions in the media, especially those with registered shooting areas, and the necessity of editing analyzes with the sensitivity of the principles of heritage protection have emerged.
ADAPTIVE RE-USE OF THE SAMSUN HAMİDİYE HOSPITAL
Authors: AKSOY Ercan
Published: May 2023

Aim: After the deterioration of Samsun Hamidiye Hospital due to the fire in 2007, it is aimed to determine the deterioration of the hospital, make restoration decisions, and ensure that it is kept alive by giving a new function. Method: In the study, modern and traditional methods were used to create survey drawings, and the deteriorations and changes in the building were identified. A literature and archive review was conducted to obtain information about the building, a restitution proposal was introduced, and conservation and functioning decisions were made accordingly. Findings: It was determined that the major problems that occurred in the hospital building were caused by add-ons and fire, and then the deterioration began due to abandonment. It was understood that it is a more correct approach to transform it to its original state, and keep the building alive by adaptive re-use. Conclusion: Hamidiye Hospitals are important since they reflect the buildings of a specific period. It was understood that the building, which was out of use due to reasons of improper intervention and fire, is about to collapse due to abandonment. For this reason, it was decided that its conservation will be more appropriate by a timely intervention and adaptive re-use.
Sacciolepis Nash (Poaceae: Panicoideae: Paniceae) – a new genus to the flora of Russia
Authors:   A.V. Zhirmunsky National Scientific Center of Marine Biology FEB RAS, Chubar Elena A. , Probatova Nina S. ,   Federal Scientific Center of the East Asia Terrestrial Biodiversity FEB RAS
Published: May 2023

A new genus Sacciolepis (Poaceae), represented by S. indica (L.) Chase, was discovered in the vicinity of the Nature Monument "Golubinyi Utyos" (Dove Cliff), Khasan District, Primorye Territory, Russia. The description of the species is given, its habitat and ecological and cenotic features are characterized.
Nina Sergeevna PROBATOVA, 2 August 1939 – 3 March 2023
Authors:   V.L. Komarov Botanical Institute RAS, Tatanov Ivan V. , Olonova Maria V. ,   National Research Tomsk State University, Ovchinnikova Svetlana V. ,   Central Siberian Botanical Garden SB RAS, Krivenko Denis A. ,   Siberian Institute of Plant Physiology and Biochemistry SB RAS
Published: May 2023

Memorial paper dedicated to Nina Probatova.
Publications by Nina Sergeevna PROBATOVA, 1939–2023
Authors: Krivenko Denis A.
Published: May 2023

Electronic supplement to the paper: Nina Sergeevna PROBATOVA, 2 August 1939 – 3 March 2023. Botanica Pacifica 12(1):189–198
Rupture Directivity of the 25 October 2022 Mw 5.1 Alum Rock Earthquake
Authors: Hirakawa Evan , Parker Grace A. , Baltay Annemarie , Hanks Thomas
Published: May 2023

The 25 October 2022 Mw 5.1 Alum Rock earthquake shows strong evidence for southeast rupture directivity along the central Calaveras fault (CCF), as indicated by observed ground motions and simulated kinematic ruptures. Peak ground accelerations (PGAs) and peak ground velocities (PGVs) are notably higher to the southeast, with an order of magnitude difference for stations at the same distance but different azimuths. In addition, PGAs are lower than that predicted by ground-motion models by a factor of 3 on average in all the directions, indicating a low stress drop (∼1.57 MPa). Directivity function modeling and ground-motion simulations both indicate rupture propagation to the southeast with rupture velocity between 2.3 and 2.5 km/s. We suggest that the southward rupture propagation and relatively low stress drop may be typical of M ∼5 earthquakes on this portion of the CCF.
The IDB Digital Credential Framework: Principles and Guidelines for Creating and Issuing Credentials
Authors: Porto Stella C. , Presant Don
Published: May 2023

Digital badges have emerged as an integral aspect of various capacity building opportunities offered by IDB, gaining widespread recognition among both internal and external clients, despite their innovative application in the region. As of January 2023, IDB has issued over 200,000 badges, with the majority awarded in the past two years. The IDB Digital Credential Framework serves as a vital reference tool and roadmap for acknowledging knowledge acquisition and continuous learning through digital credentials within the IDB Group, partner organizations, and citizens of the Latin America and Caribbean (LAC) region. This Technical Note outlines the Framework's context and purpose, its alignment with BIDAcademy and the IDB Group, and its potential to influence and shape international practice for digital credentials beyond traditional academic recognition.
Влияние напряжения на увеличение срока службы свинцово-кислотных аккумуляторов
Authors: Дубкова Е.С.
Published: May 2023

Увеличение зарядного напряжения и уменьшение времени для достижения максимальной его величины свидетельствует об ухудшении состояния аккумуляторов.
Анализ деловой активности и рентабельности деятельности предприятия
Authors: Степанова Т.А. , Воронина М.С.
Published: May 2023

В статье рассмотрена сущность деловой активности предприятия. Проведен анализ деловой активности и рентабельности деятельности ЗАО «Маяк» Петропавловского района Воронежской области. На основе проведѐнного анализа выявлены факторы и резервы его развития, предложено ряд мероприятий по увеличению показателей.
Подходы к оценке рыночной стоимости предприятия: отечественная и зарубежная практика
Authors: Худова К.Е. , Туктарова Л.Р.
Published: May 2023

В статье рассмотрены различные подходы оценки рыночной стоимости предприятия в практике оценки бизнеса, проведена сравнительная характеристика методов отечественной и зарубежной практики оценки стоимости предприятия, охарактеризованы методы и модели оценки
Особенности управления человеческими ресурсами в организации
Authors: Якупова Л.Р. , Апокина К.В.
Published: May 2023

Управление человеческими ресурсами является одной из наиболее важных составляющих в системе управления современной организацией, способной многократно повысить ее эффективность, обеспечить конкурентоспособность и стабильность. Данная статья раскрывает особенности современного опыта управления человеческими ресурсами, раскрывает их сущность, структуру и факторы, влияющих на их функционирование.
Органы опеки и попечительства как одна из сторон семейных споров
Authors: Беглецов Г.М. , Прошин В.В.
Published: May 2023

Данная работа посвящена изучению деятельности органов опеки и попечительства и выступления данного органа в семейный правоотношениях. Автор рассматривает участие органов опеки и попечительства в защите имущественного положения несовершеннолетних граждан. В настоящей научной работе изучена научная литература, а также нормативно-правые акты, посвященные правовому регулированию представленных вопросов. Также при изучении указанной тематики была проанализирована судебная практика. В заключении настоящей работы сформулированы основные выводы и представлены предложения по совершенствованию отечественного законодательства в данной области.
Анализ диссертационных исследований, посвящѐнных вопросам признания и исполнения иностранных судебных решений
Authors: Гапонов М.Д.
Published: May 2023

Проводится ретроспективный анализ диссертационных исследований на постсоветском пространстве и в современной отечественной научно-исследовательской доктрине, посвящѐнных вопросам признания и исполнения иностранных судебных решений. Резюмируется, что сейчас отсутствует всестороннее комплексное исследование, в котором бы был проведен единовременный комплексный всесторонний анализ международного, регионального, интеграционного, национального и отечественного опыта признания и приведения в исполнение решений иностранных судов.
Некоторые особенности налогообложения индивидуального предпринимателя
Authors: Зенцов Н.А. , Юшко А.В.
Published: May 2023

В данной статье сделан акцент на некоторых особенностях налогообложения индивидуальных предпринимателей, отмечены проблемы в законодательстве отечественного права. Стоит отметить, что тема очень важна в настоящее время, многие исследователи и ученые делают акцент на рассмотрении налогового режима ИП. Исследуется научная литература по заданной проблеме, а также практический отечественный опыт. В свою очередь, статья рассчитана на широкий круг читателей, поскольку она является актуальной в настоящее время.
Особенности правового обеспечения надзора в учреждениях УИС на современном этапе
Authors: Ковалев О.Г. , Восканян Ш. В.
Published: May 2023

В статье анализируются особенности правового обеспечения надзора в учреждениях УИС на современном этапе ее развития, который рассматривается как система мер организационно-практического характера, обладающая специфическими элементами, закрепленными в законодательных и ведомственных нормативных правовых актах. Также отражаются некоторые проблемные вопросы влияния режима и надзора на обеспечение безопасности учреждений УИС.
Роль и значение обысковой и досмотровой работы в обеспечении режима содержания под стражей подозреваемых и обвиняемых
Authors: Ковалев О.Г. , Михайлова А.М.
Published: May 2023

В статье рассматриваются значение и особенности организации обысковой и досмотровой работы при обеспечении режима содержания под стражей подозреваемых и обвиняемых. Проанализированные основные теоретико-правовые подходы в данной сфере уголовно-исполнительных правоотношений, законодательные и ведомственное нормативноправовое регулирование.
Особенности применения меры пресечения запрет определенных действий в уголовном судопроизводстве России
Authors: Марченко А.В. , Марченко В.В.
Published: May 2023

В настоящей статье, авторы на основе современной судебной практики, рассматривают применяемую в уголовном судопроизводстве меру пресечения запрета определенных действий; раскрываются порядок ее избрания и предельные сроки применения; анализируются последствия ее нарушения подозреваемым, обвиняемым; даѐтся характеристика запретам, налагаемым на подозреваемого, обвиняемого судебным решением. Сформулированы предложения, направленные на оптимизацию механизма применения запрета определенных действий.
Cходства и различия, а также история римского и российского гражданских процессов
Authors: Руднев В.Р.
Published: May 2023

Римское право является родоначальником всех правовых систем в странах, которые относятся к романно - германской правовой семье, к которой относится и Россия. Следовательно, основа ведения гражданского процесса также исходит из Рима, хоть и потерпело колоссальные изменения, подстраиваясь под современные реалии. А что схоже и различно между ведением процесса в современной России и Древнем Риме попытаемся разобраться в данной статье.
Особенности рассмотрения судами индивидуальных трудовых споров о предоставлении гарантий и компенсаций
Authors: Семѐнова А.А.
Published: May 2023

В рамках данной статьи рассмотрены вопросы, связанные с особенностями судебного разрешения трудовых споров. Освещены процессуальные особенности судебного рассмотрения трудовых споров, а также подробно рассмотрен вопрос, связанный с особенностями предоставления компенсаций за задержку заработной платы работника, с примерами судебной практики.
Предупреждение домашнего насилия: отечественный и зарубежный опыт
Authors: Хворост А.С. , Безуглый С.Н
Published: May 2023

В статье рассматриваются вопросы предупреждения домашнего насилия, анализируются количественные данные этого явления. Рассмотрены отечественный и зарубежный опыт правовой регламентации мер, направленных на предупреждение домашнего насилия.
Алгоритм расчета к-кратной совместной значимости в технологии логиковероятностного моделирования
Authors: Морозов В.И.
Published: May 2023

В технологии логико-вероятностного моделирования для оценки важности отказов элементов сложных технических систем (СТС) применяются показатели одно, двукратной и ккратной значимости. В данной статье приведен алгоритм расчета к-кратной совместной значимости в общем виде, который позволяет существенно сокращать объемы расчета при проведении исследований влияния некой совокупности отказов элементов на СТС.
Анализ прочности детали «червяк»
Authors: Кондрашкин А.С. , Ефанов С.А , Борискин С.И.
Published: May 2023

Статья посвящена анализу статической прочности детали «червяк». Анализ осуществляется методом конечны элементов, а в роли среды моделирования используется SOLIDWORKS Simulation. Созданы граничные условия по перемещениям обеспечивающие вычислительную эффективность, а также адекватность получаемых решений. Результаты анализа напряженнодеформированного состояния представлены в наглядной форме, пригодной для оценки.
К исследованию задачи о синхронизации квазигармонического осциллятора с полиномиальной нелинейностью асимптотическим методом
Authors: Антоновская О.Г. , Бесклубная А.В.
Published: May 2023

Многие области физики и техники полностью базируются на колебательных явлениях. В теории нелинейных колебаний особенно отчетливо проступает влияние потребностей физики на развитие математических методов. Применение линейных схем к исследованию нелинейных колебательных процессов достаточно долго представляло собой основной подход к решению нелинейных задач. Однако такое упрощение может привести к определенным как количественным, так и качественным ошибкам, т.е. аппарат линейной теории оказывается недостаточным. В предложенной работе представлено исследование методом приближенных точечных отображений квазигармонического осциллятора, являющегося математической моделью радиотехнической системы. Приводятся явно заданные функции последования точечного отображения, при построении которого используются асимптотические методы: метод Ван-дерПоля, метод последовательных приближений, а также результаты их изучения.
Компьютерное моделирование стационарного теплового режима силового сухого трансформатора
Authors: Киснеева Л.Н.
Published: May 2023

В данной работе рассматривается цифровое моделирование теплового режима силового трансформатора «ТСЛ-1000/10», обусловленное перспективностью применения компьютернопрограммных продуктов с функцией реализации математических численных реш"ений методом конечных элементов, позволяющих минимизировать трудоемкость и времязатратность традиционных тепловых расчетов, используемых в задачах оценки и контроля состояния эксплуатируемого электрооборудования.
To the question of the study of massive forest stands in the vicinity of khutor Kizinka
Authors: Primakov N.V. , Pikalova N.A. , Volkov M.I. , Akimova A.A. , Golubeva E.A.
Published: May 2023

The work is devoted to the study of massive forest plantations in the vicinity of khutor Kizinka. Several studies have been conducted. The sanitary condition of tree species growing on the territory of the natural monuments ―Mount Kizinchi‖ and ―Dolmen Tract‖ in the valleys of the Kizinchi and Khodz rivers is assessed. The species composition characteristic of this area is revealed. Information on the bonite, number and condition of forest plantations are given. Conclusions were drawn on the general condition of the forests. Recommendations for improvement of the area forestry are formed.
Мониторинг микробного загрязнения учебно-научного Модуля чистых помещений
Authors: Берестина А. В. , Бахвалов А. В.
Published: May 2023

Окружающая среда при производстве лекарственных средств должна обеспечивать минимальный риск микробного загрязнения продукта. Нами были изучены закономерности изменения уровня микробного загрязнения в чистых помещениях на примере учебно-научного Модуля чистых помещений Отделения биотехнологий ИАТЭ НИЯУ «МИФИ» (Обнинск). Показано, что уровень загрязнения рабочих поверхностей увеличивается при наличии в помещениях работающего персонала. Степень микробного загрязнения воздушной среды в зависимости от вида выполняемых работ и количества персонала изменяется незначительно. Подтверждено соответствие исследуемых чистых помещений классу чистоты D по микробиологической чистоте. Сделан вывод о необходимости чаще осуществлять контроль микробного загрязнения помещений, а также усилить санитарно-гигиенические мероприятия для устранения источников спорообразующей микрофлоры.
A broad-range PCR technique for the diagnosis of culture-negative osteomyelitis
Authors: Yolshin Nikita D.
Published: May 2023

Osteomyelitis is a rare disease that is often caused by an infection. In case of microbiology analyses failure, molecular assay seems appropriate for the identification of the pathogen. Broad-range PCR is a popular tool to amplify the gene of 16S ribosomal RNA – the component of the 30S subunit of the bacterial ribosome present in various species. The subsequent sequencing of the amplified gene enables scientists to determine the bacteria species. In this review, we discuss studies and case reports where the osteomyelitis causative agent was revealed by means of broad-range PCR. The purpose of the analysis is to assess the relevance and significance of this method for the diagnosis of osteomyelitis in patients. Numerous successful applications of wide-range PCR followed by sequencing in order to identify the causative agent of osteomyelitis have proven that this method is a useful tool in cases where the culture analyses showed negative results.
Three cases of Actinomyces isolation from the eye lesions of patients with a chronic and recurrent ophthalmic infection
Authors: Kirti Madhavi , Sharma Bhawna , Gajashree Samikkunnu
Published: May 2023

Actinomycosis is an indolent, slowly progressive infection caused by Gram-positive facultative anaerobic bacteria from the genus Actinomyces. These bacteria have been reported as a cause of ophthalmic infections such as endophthalmitis, keratitis, and canaliculitis. The objective of the present study was to investigate the pattern and antibiotic sensitivity profile of anaerobes isolated from lesions in the medial canthus of the eye.

Three pus aspirate samples (from eye) were delivered to a microbiology laboratory in a strict anaerobic condition in Robertson Cooked Meat media (RCM). The samples were inoculated on Blood Agar and incubated anaerobically in a Gas Pack Jar incubator at 5%-10% CO2 and in aerobic condition at 37°C. Pure colonies isolated on anaerobically incubated plates were identified by the VITEK® 2 COMPACT system. Antibiotic sensitivity testing was conducted using an Epsilometer-strip test.

Three isolates identified and confirmed with the help of VITEK® 2 were Actinomyces israelii, Actinomyces odontolyticus, and Actinomyces meyeri. All three species of Actinomyces were sensitive to Vancomycin, Moxifloxacin, and Imipenem, but they were resistant to Metronidazole.

Since there have been several cases of anaerobic ophthalmic infections reported to date, samples from patients with chronic eye infections should be analyzed for anaerobic culture for correct diagnosis and proper treatment. Moxifloxacin but not Metronidazole is a suitable drug for the treatment of anaerobic eye infection.
Percepções de Mudanças Climáticas no contexto formal da educação: um olhar para as publicações da plataforma EArte
Authors: Palmieri Mayara , Das Flores de Azevedo Ruan , Gomes dos Santos Raquel , De Souza Izabela
Published: May 2023

Este trabalho buscou identificar as percepções dos sujeitos de pesquisa a respeito do tema Mudanças Climáticas a partir da análise de conteúdo dos trabalhos de Educação Ambiental publicados na plataforma EArte, apresentando, assim, o Estado da Arte. Dentre os dez trabalhos encontrados, essas percepções foram identificadas em oito deles. As publicações foram analisadas a partir de duas categorias - professores e alunos. Verificou-se que existe uma percepção de natureza antrópica sobre as Mudanças Climáticas, influenciada pela mídia e com uma visão de Educação Ambiental conservacionista e resolutiva. Por fim, concluiu-se que, apesar da existência de práticas de Educação Ambiental que tratam das Mudanças Climáticas, o número baixo de publicações encontrado pode ser indicador de ausência de interesse por pesquisas do gênero, de poucos centros de formação e de insuficiência de diálogo entre a universidade com os problemas socioambientais reais da população.
A Educação Ambiental e a Pedagogia Waldorf no Ensino Fundamental
Authors: Passaes Galdino Ana Paula , Bach Junior Jonas , Rabinovici Andrea
Published: May 2023

Este artigo objetiva compreender como a Educação Ambiental (EA) acontece no currículo e na atuação das Escolas de Pedagogia Waldorf, (PW) no Ensino Fundamental. As ferramentas, estratégias e metodologias orientadas às iniciativas de EA, que visam mudanças de atitudes e comportamentos voltados à relação ser humano/natureza, foram trazidas ao contexto das Escolas Waldorf para verificar possíveis correspondências destas com a PW em suas abordagens e orientações curriculares. O presente estudo é derivado de pesquisa de mestrado e aconteceu com base na investigação de referencial teórico e entrevistas semiestruturadas com professores e formadores de professores de PW e analisadas com recursos da análise de conteúdos adaptada de Bardin (1997). Conclui-se que a EA recebe maior atenção de pesquisadores, de forma contínua e não ocasional, tendo seus diversos matizes como possibilidades de trabalho. Na PW não há tradição de estudos contínuos, há ainda muito por construir, sendo as bases da PW conscientes da busca pela saúde humana e planetária. O ferramental da EA é utilizado e existem algumas práticas comuns e muitas possibilidades para serem desenvolvidas na PW, há necessidade de sistematização, estudo, orientação de educadores para atualização curricular e novas práticas, podendo a EA ser bastante útil, para além do que já ocorre. É fundamental que haja investimento na formação de professores, permitindo que se apropriem das possibilidades que as orientações curriculares disponibilizam. A busca da autoeducação, quanto a sua relação individual com o restante da natureza pode diversificar a prática pedagógica.
Strojna rez v intenzivnih nasadih
Authors: Štampar Franci
Published: May 2023

Strojna rez jablanovih nasadov predstavlja nov ukrep z namenom povečevanja učinkovitosti pridelave jabolk, povečevanja kakovosti plodov ter zmanjševanja izmenične rodnosti. V intenzivnih nasadih jablan prevladuje gojitvena oblika ozko vreteno, ki je še posebej primerna za izvedbo strojne rezi. Strojna rez nikoli popolnoma ne zamenja ročne rezi, jo pa močno zmanjša. Prvo leto izvedbe ukrepa v povprečju zmanjša 40 % ur ročne rezi, v naslednjih letih pa ročno korekturno rez zmanjšamo celo do 60%, kar predstavlja znaten prihranek stroškov pridelave. Izvedba strojne rezi pozitivno vpliva na rast in razvoj dreves, kar se kaže v zožanju krošnje in kontrole rasti vrha, boljši penetraciji svetlobe v krošnjo, uspešnejši izvedbi strojnega redčenja plodov, lažji izvedbi varstva pred boleznimi in škodljivci, boljši diferenciaciji rodnih brstov za naslednje leto ter večji količini in kakovosti plodov. Za uspešno izvedbo strojne rezi je pomembno upoštevati ustrezen čas izvedbe. V praksi se je izkazalo, da so pozitivni učinki rezi največji, ko ukrep izvedemo po obiranju.
Skladiščenje jabolk v dinamični atmosferi
Authors: Zlatić Emil
Published: May 2023

Tehnologija skladiščenja v dinamični atmosferi odpira številne nove možnosti k izboljšanju kakovosti sadja med skladiščenjem. Razvoj sodobnih in občutljivejših senzorjev omogoča, da ključne parametre skladiščenja dinamično prilagajamo fiziološkemu stanju plodov, kar pomeni, da vsebnost kisika v skladiščni atmosferi uravnavamo s preprečevanjem anaerobnega metabolizma v plodovih. Dosedanje izkušnje in rezultati raziskav kažejo, da lahko s tovrstnim pristopom v celoti odpravimo porjavenje kože plodov (scald). Optimirana vsebnost kisika pozitivno vpliva prav tako na ostale parametre kakovosti, kot so npr. trdota mesa plodov, barva, vsebnost kislin in sladkorjev ter prisotnost bolezni jabolk. V prispevku so predstavljeni osnovni koraki za uspešno skladiščenje jabolk v dinamični atmosferi. Prikazani so ključni parametri skladiščenja za jabolka sorte 'Gala', 'Granny smith' in 'Zlati delišes'.
Estrategias de sobrevivencia de los pueblos indígenas en aislamiento y contacto inicial : el caso de un matsés en Iquitos durante la pandemia de la COVID-19
Authors: Dunu Maya Ángel Uaqui
Published: May 2023

Este artículo es una reflexión acerca de las estrategias de sobrevivencia de los pueblos indígenas en la Amazonía peruana desde el contacto con la cultura occidental; enfocado principalmente a las enfermedades foráneas. Mediante el uso del testimonio como herramienta, conoceremos la experiencia de Ángel Dunu, docente y especialista matsés quien radica en la ciudad de Iquitos. Ángel relata episodios de su infancia y cómo su padre Salomón reaccionó a una posible epidemia de sarampión en la década de 1980.
El saber popular en Loreto se impuso a la COVID-19
Authors: Rivas Ruiz Roxani
Published: May 2023

Hubo este año epidemia de calenturas y fríos, de que murieron bastantes. En Yurimaguas, escribió Deubler que encontrándose un indio con su mujer cerca de San Rosa con dos mozos desconocidos, le preguntaron estos que si estaba bueno; respondió que sí. Volvió, y esa noche le comenzó la calentura; con que decían que aquellos mozos aparecidos eran el Mal.
Jakonma niwe isin : las respuestas del pueblo shipibo-konibo frente a la pandemia del coronavirus
Authors: Favaron Pedro
Published: May 2023

Yo me llamo Chonon Bensho, que significa «golondrina de los campos medicinales». Soy una legítima heredera del saber de mis ancestros, los antiguos sabios meraya del pueblo shipibo-konibo. Escribo este testimonio reflexivo junto a mi esposo, Pedro Favaron, complementándonos, como deben siempre hacer el marido y la mujer cuando piensan de forma saludable y actúan según las antiguas enseñanzas.
Indiferencia
Authors: Montalbetti Mario
Published: May 2023

Ferdinand de Saussure concluyo su tercer Curso de Lingüistica General de 1910 a 1911 con las siguientes palabras: «De las incursiones que acabamos de hacer por los dominios limitrofes de nuestra ciencia, se desprende una ensehanza enteramente negativa, pero tanto mas interesante cuanto concuerda con la idea fundamental de este curso: la linguistica tiene por unico y verdadero objeto la lengua considerada en si misma y por si misma». Pero ¿por que habria de ser esta enseñanza «enteramente negativa»? ¿Dónde yace la negatividad en el estudio de la lengua «en y por si misma»? Para los lectores del Curso de Saussure hay una respuesta a mano: «...en la lengua no hay mas que diferencias. Todavia mas: una diferencia supone, en general, terminos positivos entre los cuales se establece; pero en la lengua solo hay diferencias sin terminos positivos». Existe, sin embargo, un hecho
Changes in Health Insurance During COVID-19 Among a U.S. National Cohort of Cisgender Gay and Bisexual Men and Transgender Individuals
Authors: D’Angelo Alexa B. , Zohra Fatima , Westmoreland Drew A. , Grov Christian
Published: May 2023

The extant data suggest that LGBT communities were disproportionately impacted by the economic ramifications of the pandemic and were more likely to report being uninsured throughout the first two years of the pandemic. Additionally, these groups are at heightened vulnerability for several health conditions that require insurance to manage or prevent. Thus, there is a need to assess changes in pandemic-era insurance coverage among these populations. This study uses data collected as part of the Together 5000 study, a U.S. national, internet-based cohort study of cisgender (cis) men, trans men, and trans women who have sex with men. We analyze insurance data across three different assessments between 2019 and 2021, exploring changes in insurance coverage and type. Among our sample, 6.4% lost their insurance in 2020 because of the pandemic. Insurance loss was associated with living in a state that had not expanded Medicaid, race/ethnicity, employment status, and income. Among those who lost their insurance in early 2020, most (59.2%) reported gaining insurance by 2021, with those living in nonexpanded states less likely to gain insurance. Finally, those who were uninsured prior to the pandemic were less likely to report gaining insurance by 2021 when compared with those uninsured as a result of the pandemic. This suggests that there are uninsured cis gay and bisexual men and transgender individuals (GBT) that continue to go unreached by policies to assuage uninsurance. Further policy intervention is needed to address uninsurance among LGBT individuals, which has important implications for addressing health disparities among these populations.
APRESENTAÇÃO
Authors: Costa-Maciel Débora Amorim Gomes da , Storto Letícia Jovelina , Magalhães Tânia Guedes , Bueno Luzia
Published: May 2023

Apresentação do dossiê.
ORALIDADE, ARGUMENTAÇÃO E TECNOLOGIAS DIGITAIS NO PROJETO POLÊMICAS EM DEBATE
Authors: Batista Júnior José Ribamar Lopes , Peixoto Gercivaldo Vale
Published: May 2023

O Polêmicas em Debate visa sanar a dificuldade de estudantes do Ensino Médio em argumentar a partir de situações relacionadas ao mundo do trabalho e exercício da cidadania. Neste trabalho, apresentamos resultados das edições realizadas nos anos de 2020 a 2022. Alicerçado no conceito de letramento (BARTON, 2007), o projeto é composto por seis etapas, após o qual espera-se que os discentes tenham incremento na capacidade argumentativa, compreensão social e desenvolvimento ético.  Os resultados demonstram que o projeto promove a integração dos alunos com os debates atuais e geram a melhoria da autopercepção como cidadãos detentores de voz e protagonismo.
ELEMENTOS PARA UMA PEDAGOGIA DA ORALIDADE NA ESCOLA
Authors: Nonato Sandoval
Published: May 2023

O problema da oralidade (e de outros sistemas semióticos, outras linguagens) na escola inscreve-se em um conjunto de pautas silenciadas ou deixadas historicamente em plano acessório no currículo e nas práticas escolares. Neste ensaio, proponho discutir sobre tal problema com o propósito de: a) qualificar o estatuto da oralidade nos processos de escolarização e no percurso histórico de formação do ensino de língua portuguesa, na escola brasileira; e b) discutir sobre os novos lugares da oralidade nos currículos e nas práticas escolares, considerando o fenômeno mais recente de inserção da poesia Slam – como prática comunicativa e produto cultural de natureza multimodal – entre os muros da escola.
Formation Reaction of 17α(chlorovinyl-3-methyl-butene)estradiol Through the Addition Reaction of a Terminal Alkyne to Ethinylestradiol With a ZnCl2 Catalyst
Authors: Siwu Omega , Rumampuk Rymond J. , Oktavia Budi , Pongoh Emma J. , Tengker Soenandar M.T , Paat Vlagia I
Published: May 2023

The addition reaction had been done on the terminal alkynes of 17α-ethynylestradiol with ZnCl2 and HCl catalyst mediated by dichloromethane. The reaction conditions were carried out at a temperature of 70°C for 29 h, the separation of the reaction properties was carried out using Gravity Column Chromatography, and the reaction products were identification using by Nuclear Magnetic Resonance (NMR). The catalyst used was a cationic ligand coordinate, where Zn acts as the central ion and 2-propanol as the ligand. In the reaction mechanism, the reaction begins with the formation of dimeric ether. ZnCl3 catalyst acts as Lewis acid which converts alcohol to dimeric ether and forms a complex with ZnCl3. The nucleophilic terminal alkyne then attacks the C-O bond of the ether to form a vinyl carbocation which then attracts a chlorine atom from ZnCl3 which was complex bound with ether, resulting in a reaction product of 17α(chlorovinyl-3-methyl-butene)estradiol
Valuation of the Water Protection Function of Forest Territories and Income Allocation: a Case Study of Bulgaria
Authors: Shuleva Nevena , Kolev Konstantin
Published: May 2023

The owners of forests with water protection functions in Bulgaria do not receive compensation for their limited right to use wood and non-wood forest products from the forest areas they own. At the same time, the contribution derived from forests with water protection functions is received by water users and water consumers, whereas the costs of managing the forests are borne by their owners. The problem thus defined is not a forestry one, but an economic one, and the purpose of this paper ensues therefrom, namely to propose and test a methodology for valuating the produc-tion function of forest areas with water protection function in Bulgaria, allowing a fair distribu-tion of income between the forest owner and the user of forest ecosystem services. The methodol-ogy is based on the form of forest management and the analytical expression of the economic rela-tionship between a forest owner and a user of forest ecosystem services, constructed using Schen-rock’s formula. It has been tested with actual data on forest areas with water protection functions falling within the administrative and territorial scope of Velingrad municipality and based on the obtained results proposals have been made for the distribution of the contributions generated by forest ecosystems between the forest owner and the user of the forest ecosystem services.
New Phenolic Dimers From Plant Paeonia suffruticosa and Their Bioactivity
Authors: Meng Qian-Qian , Tong Shun-Yao , Zhao Yu-Qing , Peng Xing-Rong , Li Zheng-Hui , Feng Tao , Liu Ji-Kai
Published: May 2023

The Paeonia suffruticosa, called as 'Feng Dan', has been used for thousands of years in traditional Chinese medicine. In our chemical investigation on the root bark of the plant, five new phenolic dimers, namely paeobenzofuranone A‒E (1‒5), have been characterized. Their structures were determined by spectroscopic analysis including 1D and 2D NMR, HRESIMS, UV, and IR, as well as ECD calculations. Compounds 2, 4, and 5 showed cytotoxicity against three human cancer cell lines with IC50 values ranging from 6.7 to 25.1 μM. Compounds 1 and 2 showed certain inhibitory activity on NO production. To the best of our knowledge, the benzofuranone dimers and their cytotoxicity of P. suffruticosa are reported for the first time.
A Quantitative Study on the Effectiveness of the Governance Attributes on ‘Industry-Wise Earnings Quality’ in the UK
Authors: Aryal Rishiram , Emambocus Washad , Dhesi Gurjit , Eguruze Ebikinei Stanley
Published: May 2023

This study investigates the impact of governance variables on the earnings quality based on the industry the firm is in. it has been identified that earnings management have been practised differently by different industries. Most of the research under earnings management have focussed on holistic impacts of corporate governance variables on discretionary accruals while this study has categorised the firms based on what industry they fall on while identifying the impacts of the variables of corporate governance on discretionary accruals. Initially, this paper has studied the estimation of the value of discretionary accruals and identified that performance matched discretionary accruals as the best model as per the explanatory power of the model is higher than other models. Hence, the estimation of the earnings management has been calculated based on performance matched discretionary accruals in this research. This research has studied the impacts of the governance attributes on the earnings management categorising the firms based on the industry they are in; hence, the value of earnings management has been categorically separated; hereafter, the impact of the corporate governance factors on the value of categorically separated earnings management have been statistically analysed. This study has considered the descriptive study to compare the means, medians and standard deviations of the earnings management of various industries. Moreover, Pearson correlations and Spearman rank correlation have been used as a research tool to examine the correlation coefficients.
Use of In-situ and Ex-situ Characterization Techniques to Study the Effects of Acid Diffusion on Physical Properties of Polymer Composites.
Authors: Tamayo-Vegas Sebastian , Lafdi Khalid , Tarfaoui Mostapha , Lafdi Khalil K , Daly Mohamed
Published: May 2023

In this study various samples were fabricated by increasing the amount of CNT from 0% to 5%. The bulk mechanical properties of the samples were measured using DMA. Alternatively, the local mechanical properties were assessed using nanoindentation technique. There is a clear trend that the behavior of the material is dependent of carbon fillers before, during and after percolation threshold. The bulk mechanical properties were reduced after the percolation threshold due to CNT agglomeration. Then the samples were exposed to acid solution for one week and one month. Regardless the amount of CNT in the matrix, there is always a gradient of properties from the skin to the core of the sample. There is a net reduction of in physical properties. However, the level of degradation was a dependent of the amount of CNT in the host polymer. At higher concentration the CNTs behave as a barrier. However due to the formation of porosity around the CNT agglomerates, the acid diffusion encounters preferential path ways. . Both techniques lead to the same observation..
Evaluation of Fenugreek (Trigonella foenum graecum) Seed Powder and Moringa oleifera Leaf Meal on Production Performance and Egg Quality of Laying Hens
Authors: Tesissa Ebisa , Tamiru Metekia , Tadese Dawit Adisu , Demeke Solomon , Ababor Sebsib , Asres Azmeraw , Beyene Abegaze , Miresa Ashenafi , Wamatu Jane , Alkhtib Ashraf , Burton Emily
Published: May 2023

The effect of the addition of fenugreek seed powder and Moringa oleifera leaf meal on the production performance and egg quality of Lohmann Brown laying hens was investigated. A total of 108 Lohmann-Brown layers, 48 weeks of age, were used and randomly assigned to six experimental groups of three replicates each in a randomized design. A control diet was supplemented with 3.6 g/hen/day of Moringa oleifera leaf meal and fenugreek seed powder alone or in various proportions as follows: control diet (T1), 100% Moringa oleifera leaf meal (T2), 25% fenugreek seed powder and 75% moringa oleifera leaf meal (T3), 50% fenugreek seed powder and 50% moringa oleifera leaf meal (T4), 75% fenugreek seed powder and 25% moringa oleifera leaf meal (T5) and 100% fenugreek seed powder (T6) were added on top of the control diet. Data were analyzed using one-way ANOVA by the general linear model method, using Tukey's multiple range tests to differentiate means. According to the results, fenugreek and moringa had a crude protein content of 25.17 and 27.8%, respectively. The groups administered T4 had significantly higher mean feed intake (120.75), feed conversion rate (2.315), egg production (77.22), and egg mass (52.08) than the others. Treatment 4 had a significant (P<0.05) improvement in some egg quality traits such as shell weight, shell firmness, albumen weight, yolk weight, yolk color, and Haugh unit compared to the control. In summary, Treatment 4, a mixture of equal parts fenugreek seed powder and Moringa oleifera leaf meal, improved egg production performance and egg quality.
Endokarst Potential Assessment in the Northern Sector of Santo António Plateau (Estremadura Limestone Massif, Central Portugal)
Authors: Reis Luís , Dimuccio Luca Antonio , Cunha Lúcio
Published: May 2023

This work aims to produce a cartographic model that identifies areas with a greater probability of finding karstic caves - the endokarst potential - in the northern sector of Santo António Plateau (Estremadura Limestone Massif, Central Portugal). Geological, topographic, hydrogeological, and vegetation cover data were collected, processed, and integrated into a spatial database using a geographic information system (GIS). The location of known cave entrances in the study area was also identified from the records of local public institutions and speleological teams. Four conditioning factors were extracted from the collected data, including lithostratigraphic units, fracture density, relief energy, and land cover. In a multi-criteria decision-making analysis framework, each previously chosen conditioning factor and respective classes/categories were weighted using the analytic hierarchy process (AHP). With an agreement of 81.9%, the results of the cartographic model constructed in GIS seem to be promising, considering that the entrances of the known caves are mainly located in areas classified as having high to very high endokarst potential. This prototype of the endokarst potential map for the study area can be used in strategic and operational environmental planning (at least on a local scale), as it can assist decision-makers, competent authorities, and local speleological teams in a more accurate and thoughtful definition of the areas that should be investigated, providing a substantial reduction in times and costs field prospecting.
Long-Term Trends in Inferred Continental Background Ozone in Eastern Australia
Authors: Riley Matthew L. , Jiang Ningbo , Duc Hiep Nguyen , Azzi Merched
Published: May 2023

A better understanding of background tropospheric ozone delivers multiple benefits. Robust estimates of regional background ozone assist policy makers to understand the limits to reducing ozone by controlling anthropogenic emissions alone and assist in characterising changes in the atmospheric environment and its composition. Long time series of background ozone measurements can also help quantify the influence of human activity on the global and regional atmosphere. Background tropospheric ozone measurements representative of continental air masses are however scarce in Australia, limiting our knowledge of background atmospheric composition. Here we use k-means clustering to identify a cluster of measurements from the long-term monitoring station at Oakdale, NSW which are likely to be representative of background air. The cluster is associated with NOx-limited air masses of continental origin. From this analysis we estimate background ozone representative of Eastern Australia. We find recent (2017-2022) mean ozone mixing ratios of 28.5 ppb and identify a statistically significant (α=0.05) trend in the mean of +1.8 (1.0 – 2.8) ppb/decade. Our methods demonstrate that some long-term monitoring stations within or near urban areas can provide suitable conditions and datasets for regional Global Atmosphere Watch monitoring.