bluuebunny/crossref_metadata_2025 huggingface dataset:
A Practical Gold‐Catalyzed Route to 4‐Substituted Oxazolidin‐2‐ones from N‐Boc Propargylamines.
Authors: Lee Eun‐Sun , Yeom Hyun‐Suk , Hwang Ji‐Hyun , Shin Seunghoon
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Formation of an Isoxazole Ring from Phenylacetic Acid Amidoximes.
Authors: Vakhitov T. R. , Veretennikov E. A. , Shtabova O. V.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and anti‐HIV Studies of 2‐Adamantyl‐substituted Thiazolidin‐4‐ones.
Authors: Balzarini Jan , Orzeszko Barbara , Maurin Jan K. , Orzeszko Andrzej
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New, Facile Approach to Biologically Significant and Functionalizable Heterobiaryls (IV).
Authors: Verma Raman K. , Aggarwal Monika , Bansal Manisha , Kaur Inder Preet
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Fast and Efficient Synthesis of 10‐Aryl‐2,7‐dimethyl‐4,5‐dioxo‐3,6,9‐trioxa‐3,4,5,6,9,10‐hexahydroanthra cene under Microwave Irradiation Without Catalyst.
Authors: Gao Yuan , Tu Shujiang , Shi Feng , Wang Qian , Zhu Xiaotong , Shi Daqing
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
C—C Bond Formation by Radical Cyclization: Regioselective Synthesis of [6,6]Pyranopyran System.
Authors: Majumdar K. C. , Jana M.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Direct Palladium‐Catalyzed Alkynylation of N‐Fused Heterocycles.
Authors: Seregin Ilya V. , Ryabova Victoria , Gevorgyan Vladimir
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Novel Synthetic Methodologies. Part 139. A Rapid, High‐Yielding, and Efficient Friedlander Synthesis of Quinolines Catalyzed by 2,4,6‐Trichloro‐1,3,5‐triazine.
Authors: Das Biswanath , Damodar Kongara , Chowdhury Nikhil , Suneel Kanaparthy
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Palladium(0)‐Catalyzed Intramolecular Annulation of Alkene: Synthesis of 3‐Methylene‐2,3‐dihydro‐1H‐cyclopenta[b]quinolin‐1‐ols.
Authors: Singh R. M. , Chandra A. , Singh M. K.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Substituted Pyrrolo[3,2‐f]quinolines (IV) from 5‐Aminoindoles (I) and Diethyl Oxaloacetate.
Authors: Yamashkin S. A. , Zhukova N. V. , Romanova N. S.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis, Isomerization, and Antimicrobial Evaluation of Some Pyrazolopyranotriazolopyrimidine Derivatives.
Authors: Shamroukh Ahmed H. , Zaki Magdi E. A. , Morsy Eman M. H. , Abdel‐Motti Faiza M. , Abdel‐Megeid Farouk M. E.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Mild Method for Ullmann Reaction of 2‐Chlorobenzoic Acids and Aminothiazoles or Aminobenzothiazoles under Ultrasonic Irradiation.
Authors: Pellon Rolando F. , Docampo Maite L. , Fascio Mirta L.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Catalytic Oxidative Cyclocondensation of o‐Aminophenols to 2‐Amino‐3H‐phenoxazin‐3‐ones.
Authors: Giurg Miroslaw , Piekielska Katarzyna , Gebala Magdalena , Ditkowski Bartosz , Wolanski Marcin , Peczynska‐Czoch Wanda , Mlochowski Jacek
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 2,2′‐Bi‐2H‐3,3′‐diaryl‐1,4‐benzothiazines from α,α‐Dibromoacetophenones and o‐Aminothiophenol.
Authors: Prakash Om , Sharma Nisha , Pannu Kamaljeet
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Fused Nonaromatic Heterocyclic Systems Based on Dioxolanones (I) and Hydrazine.
Authors: Chudinov Yu. B. , Gashev S. B. , Semenov V. V.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Large Ring Macrocycles (12‐18) by Recyclable Palladium‐Complexed Dendrimers on Silica Gel Catalyzed Intramolecular Cyclocarbonylation Reactions.
Authors: Lu Shui‐Ming , Alper Howard
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Palladium‐Catalyzed Borylation of Aryl Chlorides: Scope, Applications, and Computational Studies.
Authors: Billingsley Kelvin L. , Barder Timothy E. , Buchwald Stephen L.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Syntheses and Antimicrobial Activity of Some Novel 6‐Substituted Dibenzo[d,f][1,3,2]dioxaphophepin‐6‐oxides, Sulfides, and Selenides.
Authors: Haranath P. , Kumar V. Sreedhar , Reddy C. Suresh , Raju C. Naga , Reddy C. Devendranath
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Novel Stereodefined Vinylgermanes Bearing an Ally Group or an Allenyl Group: (E)‐2‐Aryl‐1‐germylalka‐1,4‐dienes and (E)‐4‐Aryl‐5‐germylpenta‐1,2,4‐trienes.
Authors: Kato Kotaro , Senda Yoshiya , Makihara Yoshiaki , Kojima Takeshi , Kurihara Hiroyuki , Takahashi Yutaka , Nakano Taichi
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Stable Germylenes, Stannylenes, and Related Compounds. Part 7. Synthesis and Structures of Compounds Hal—Sn—OCH2CH2NMe2 (Hal = Cl or F).
Authors: Khrustalev V. N. , Zemlyansky N. N. , Borisova I. V. , Kuznetsova M. G. , Krut'ko E. B. , Antipin M. Yu.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Three New 15,16‐Seco‐cycloartane Glycosides from Cimicifuga Rhizome.
Authors: Yoshimitsu Hitoshi , Nishida Makiko , Nohara Toshihiro
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Dammarane Triterpenes from Maytenus macrocarpa.
Authors: Torpocco Virginia , Chavez Haydee , Estevez‐Braun Ana , Ravelo Angel Gutierrez
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Modification of C2,3,23,28 Functional Groups on Asiatic Acid and Evaluation of Hepatoprotective Effects.
Authors: Jeong Byeong‐Seon , Kim Young Choong , Lee Eung‐Seok
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of Valeriananoids A, B, and C via Autocatalytic Diastereoselective Domino Michael Reaction.
Authors: Fukushima Masakazu , Morii Akihiro , Hoshi Takashi , Suzuki Toshio , Hagiwara Hisahiro
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Design and Synthesis of a New, Conformationally Constrained, Macrocyclic Small‐Molecule Inhibitor of STAT3 via “Click Chemistry”.
Authors: Chen Jianyong , Nikolovska‐Coleska Zaneta , Yang Chao‐Yie , Gomez Cindy , Gao Wei , Krajewski Krzysztof , Jiang Sheng , Roller Peter , Wang Shaomeng
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Peptide Synthesis with 5‐Amino‐1‐methyl‐1H‐[1,2,4]triazole‐3‐carboxylic Acid.
Authors: Masiukiewicz Elzbieta , Rzeszotarska Barbara , Wawrzycka‐Gorczyca Irena , Kolodziejczyk Edyta
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Tandem Exploitation of Helix pomatia Glycosyltransferases: Facile Syntheses of H‐Antigen‐Bearing Oligosaccharides.
Authors: Bretting Hagen , Buck Friedrich , Jacobs Guenter , Meinke Sebastian , Scheppokat Angela M. , Thiem Joachim
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Pyrrolo‐isoquinolines Related to the Lamellarins Using Silver‐Catalyzed Cycloisomerization/Dipolar Cycloaddition.
Authors: Su Shun , Porco John A. Jr.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of the 3‐(3,4,5‐Trimethoxyphenyl)pyrrolidine (V): A New Conformationally Constrained Mescaline Analogue.
Authors: de L. Barreto Ricardo , Nascimbem Laura B. L. R. , Correira Carlos R. D.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rhusemialins A—C, New Cyclolignan Esters from the Roots of Rhus javanica var. roxburghiana.
Authors: Ouyang Ming‐An , Wein Yung‐Shung , Su Ren‐Kuan , Kuo Yueh‐Hsiung
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Efficient and Practical Total Synthesis of Aigialomycin D.
Authors: Vu Nguyen Quang , Chai Christina L. L. , Lim Kok Peng , Chia Sze Chen , Chen Anqi
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cytotoxic Polyketides from the Marine Sponge Discodermia calyx
Authors: Shinde Pramod B. , Mansoor Tayyab A. , Luo Xuan , Hong Jongki , Lee Chong‐O. , Jung Jee H.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Single Molecule Magnet with Single Lanthanide Ion
Authors: Ishikawa Naoto
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Applications of 29Si NMR Parameters
Authors: Wrackmeyer Bernd
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Role of Cationic Gold in Supported CO Oxidation Catalysts
Authors: Fierro‐Gonzalez Juan C. , Guzman Javier , Gates Bruce C.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Preservation of the Activity of Supported Gold Catalysts for CO Oxidation
Authors: Moreau Francois , Bond Geoffrey C.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Oxidation State of Oxide Supported Nanometric Gold
Authors: Wang J. G. , Hammer B.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reactivity and Sintering Kinetics of Au/TiO2(110) Model Catalysts: Particle Size Effects
Authors: Parker Stephen C. , Campbell Charles T.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Mesoporous Silica Supports for Improved Thermal Stability in Supported Au Catalysts
Authors: Gabaldon John P. , Bore Mangesh , Datye Abhya K.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Progress Towards the Commercial Application of Gold Catalysts
Authors: Corti Christopher W. , Holliday Richard J. , Thompson David T.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reactions of Transition Metal Azido Complexes and Their Reaction Products
Authors: Straehle Joachim
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Pentafluorophenyl Copper: Aggregation and Complexation Phenomena, Photoluminescence Properties, and Applications as Reagent in Organometallic Synthesis
Authors: Jaekle Frieder
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Recent Developments on the Chemistry of Aliphatic Nitro Compounds under Aqueous Medium
Authors: Ballini Roberto , Barboni Luciano , Fringuelli Francesco , Palmieri Alessandro , Pizzo Ferdinando , Vaccaro Luigi
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Naphtho‐1,4‐quinones
Authors: Couladouros E. A. , Strongilos A. T.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Solvent‐Free Photosynthesis of Cyclobutanes: Photodimerization of Crystalline Olefins
Authors: Natarajan Arunkumar , Ramamurthy V.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Design and Synthesis of Cell‐Penetrating Peptides
Authors: Jiang Yang , Soomets Ursel , Langel Ulo
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Non‐Conventional Glycosidic Linkages: Syntheses and Structures of Thiooligosaccharides and Carbohydrates with Three‐Bond Glycosidic Connections
Authors: Szilagyi Laszlo , Varela Oscar
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Functionalization of Indoles Through Rhodium‐Catalyzed Reactions
Authors: Patil Shivaputra , Patil Renukadevi
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Soluble Protein Oligomers as Emerging Toxins in Alzheimer′s and Other Amyloid Diseases
Authors: Ferreira Sergio T. , Vieira Marcelo N. N. , De Felice Fernanda G.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Combinatorial Chemistry Underpinning Drug Discovery and Development
Authors: Bernardes Lilian Sibelle Campos , Silva Carlos H. T. P. , Taft Carlton A. , Carvalho Ivone
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Two‐Dimensional Electronic Conjugation: Statics and Dynamics at Structural Domains Beyond Molecular Wires
Authors: Opsitnick Elizabeth , Lee Dongwhan
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
When Single‐Site Polymerization Catalysis Meets Chirality: Optical Activity of Stereoregular Polyolefins.
Authors: Carpentier Jean‐Francois
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Olefin Metathesis of Amine‐Containing Systems: Beyond the Current Consensus.
Authors: Compain Philippe
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Synthesis of Heterocycles Using Cascade Chemistry
Authors: Bur Scott K. , Padwa Albert
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Aminoisoxazoles: Preparations and Utility in the Synthesis of Condensed Systems
Authors: Kislyi V. P. , Danilova E. B. , Semenov V. V.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Isothiazolium Salts and Their Use as Components for the Synthesis of S,N‐Heterocycles
Authors: Wolf J. , Schulze B.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Practical Synthesis of NPY Antagonist Drug Candidates for Treatment of Obesity
Authors: Itoh Takahiro , Mase Toshiaki
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chemistry and Biological Activity of Vibsane‐Type Diterpenes
Authors: Fukuyama Yoshiyasu , Esumi Tomoyuki
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthetic Studies of Fluorine‐Containing Compounds for Household Insecticides
Authors: Mori Tatsuya , Matsuo Noritada
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cationic Rhodium(I)/BINAP‐Type Bisphosphine Complexes: Versatile New Catalysts for Highly Chemo‐, Regio‐, and Enantioselective [2 + 2 + 2] Cycloadditions
Authors: Tanaka Ken
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Palladium‐Catalyzed Cascade Reactions of Highly Activated Olefins
Authors: Patil Nitin T. , Yamamoto Yoshinori
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Macrocyclic Shellfish Toxins Containing Spiroimine Moieties
Authors: O'Connor Patrick D. , Brimble Margaret A.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Application of Linear Free Energy Relationships to Chemical Kinetics
Authors: Makitra R. G. , Turovsky A. A. , Zaikov G. E.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Supramolecular Bioinorganic Chemistry: Model Complexes of Cytochrome c Oxidase Meet Functional Surfaces
Authors: Broering Martin
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chemical Constituents of Plants from the Genus Cerbera
Authors: Shen Li‐Ru , Jin Shu‐Min , Yin Bao‐Wei , Du Xiu‐Fang , Wang Yong‐Li , Huo Chang‐Hong
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Biology‐Enabling Inositol Phosphates, Phosphatidylinositol Phosphates and Derivatives
Authors: Conway Stuart J. , Miller Gavin J.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Microcins, Gene‐Encoded Antibacterial Peptides from Enterobacteria
Authors: Duquesne Sophie , Destoumieux‐Garzon Delphine , Peduzzi Jean , Rebuffat Sylvie
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Macrocyclization Strategies in Polyketide and Nonribosomal Peptide Biosynthesis
Authors: Kopp Florian , Marahiel Mohamed A.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Ubiquitous Carrier Protein — A Window to Metabolite Biosynthesis
Authors: Mercer Andrew C. , Burkart Michael D.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ptaquiloside, the Major Toxin of Bracken, and Related Terpene Glycosides: Chemistry, Biology and Ecology
Authors: Yamada Kiyoyuki , Ojika Makoto , Kigoshi Hideo
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Bacterial Volatiles: The Smell of Small Organisms
Authors: Schulz Stefan , Dickschat Jeroen S.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Simple Indole Alkaloids and those with a Nonrearranged Monoterpenoid Unit
Authors: Higuchi Kazuhiro , Kawasaki Tomomi
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Transition Metal Ions: Weak Links for Strong Polymers
Authors: Kurth Dirk G. , Higuchi Masayoshi
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Application of the Environmental Product Declaration of Waste Disposal in a Sanitary Landfill: 4 Case Studies
Authors: Del Borghi Adriana , Binaghi Laura , Del Borghi Marco , Gallo Michela
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Review of Procedures Involving Separation and Preconcentration for the Determination of Cadmium Using Spectrometric Techniques
Authors: Ferreira Sergio L. C. , de Andrade Jailson B. , Korn Maria das Gracas A. , Pereira Madson de G. , Lemos Valfredo A. , dos Santos Walter N. L. , Rodrigues Frederico de Medeiros , Souza Anderson S. , Ferreira Hadla S. , da Silva Erik G. P.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Molecular Mechanism of Emodin Action: Transition from Laxative Ingredient to an Antitumor Agent
Authors: Srinivas Gopal , Babykutty Suboj , Sathiadevan Priya Prasanna , Srinivas Priya
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
ODMR Spectroscopy of Molecular Functions in Photosynthetic Membrane Proteins
Authors: Giacometti G. , Agostini G. , Santabarbara S. , Carbonera D.
Published: October 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Efficient and Practical Process for Pd/Cu CocatalyzedHomocoupling Reaction of Terminal Alkynes Using Sodium Percarbonate as a Dual Reagent in Aqueous Media
Authors: ZHOU Lei , ZHAN Hai‐Ying , LIU Hai‐Ling , JIANG Huan‐Feng
Published: October 2007

A new process for the Pd/Cu co‐catalyzed homocoupling reaction of terminal alkynes was developed. The reaction was carried out in aqueous media with sodium percarbonate as both a clean oxidant and a base. Meanwhile, a palladium complex immobilized on a synthetic PS‐PEG400‐PPh2 resin was used as the catalyst, which may be recovered by simple filtration and reused for several times with high activity.
Thermochemistry on the Complex of Erbium Perchlorate with L‐α‐Glutamic Acid [Er2(L‐Glu)2(H2O)6](ClO4)4·6H2O(s)
Authors: DI You‐Ying , ZHANG Jian , TAN Zhi‐Cheng
Published: October 2007

A coordination compound of erbium perchlorate with L‐α‐glutamic acid, [Er2(Glu)2(H2O)6](ClO4)4·6H2O(s), was synthesized. By chemical analysis, elemental analysis, FTIR, TG/DTG, and comparison with relevant literatures, its chemical composition and structure were established. The mechanism of thermal decomposition of the complex was deduced on the basis of the TG/DTG analysis. Low‐temperature heat capacities were measured by a precision automated adiabatic calorimeter from 78 to 318 K. An endothermic peak in the heat capacity curve was observed over the temperature region of 290–318 K, which was ascribed to a solid‐to‐solid phase transition. The temperature Ttrans, the enthalpy ΔtransHm and the entropy ΔtransSm of the phase transition for the compound were determined to be: (308.73±0.45) K, (10.49±0.05) kJ·mol−1 and (33.9±0.2) J·K−1·mol−1. Polynomial equation of heat capacities as a function of the temperature in the region of 78–290 K was fitted by the least square method. Standard molar enthalpies of dissolution of the mixture [2ErCl3·6H2O(s)+2L‐Glu(s)+6NaClO4·H2O(s)] and the mixture {[Er2(Glu)2(H2O)6](ClO4)4·6H2O(s)+6NaCl(s)} in 100 mL of 2 mol·dm−3 HClO4 as calorimetric solvent, and {2HClO4(l)} in the solution A' at T=298.15 K were measured to be, ΔdHm,1= (31.552±0.026) kJ·mol−1, ΔdHm,2= (41.302±0.034) kJ·mol−1, and ΔdHm,3= (14.986±0.064) kJ·mol−1, respectively. In accordance with Hess law, the standard molar enthalpy of formation of the complex was determined as ΔfH⊖m = − (7551.0±2.4) kJ· mol−1 by using an isoperibol solution‐reaction calorimeter and designing a thermochemical cycle.
Synthesis of an Anionic Receptor Based on Phenylhydrazone Group and Its Recognition Property for Acetate
Authors: WANG Yue‐Hong , LIN Hai , LIN Hua‐Kuan
Published: October 2007

A colorimetric anion receptor was synthesized by a simple method where the phenylhydrazone moiety was need as binding sites. The anion recognition via hydrogen‐bonding interactions can be easily monitored by anion complexation induced changes in UV‐vis absorption spectra. Moreover, the hydrogen bond formation between the phenylhydrazone NH and acetate or fluoride anion was described on the basis of 1H NMR experiments.
Direct and Simultaneous Determination of Phenol, Hydroquinone and Nitrophenol at Boron‐Doped Diamond Film Electrode
Authors: ZHAO Guo‐Hua , TANG Yi‐Ting , LIU Mei‐Chuan , LEI Yan‐Zhu , XIAO Xiao‐E
Published: October 2007

The electrochemical characteristics of multi‐component phenolic pollutants, such as phenol (Ph), hydroquinone (HQ) and 4‐nitrophenol (4‐NP), were investigated on boron‐doped diamond (BDD) film electrode by differential pulse voltammetry (DPV) technique. A simple and feasible platform was accordingly established for the direct and simultaneous determination of these three phenolic pollutants. Results showed that, Ph, HQ and 4‐NP gave obvious oxidation peaks on BDD electrode at the potential of 1.24, 0.76 and 1.52 V, respectively. Each of them displayed good linear relationship between their oxidation peak currents and their corresponding concentrations in a rather wide range coexisting with one or two of the other phenolic pollutants. The detection limits of Ph, HQ and 4‐NP were estimated to be as low as 1.82×10−6, 1.67×10−6 and 1.44×10−6 mol·L−1, respectively. Therefore, a promising direct and simultaneous electrochemical determination method of multi‐component phenolic pollutants in wastewater samples was constructed successfully on BDD electrode with advantages being rapid, simple, convenient, sensitive, in situ and inexpensive.
Spin‐orbit Coupling and Intersystem Crossing in 4H‐Pyran‐4‐thione: CASSCF//TD‐B3LYP Study
Authors: LÜ Ling‐Ling , LIU Xin‐Wen , YUAN Kun , WANG Yong‐Cheng , WANG Han‐Qing
Published: October 2007

The intersystem crossing channels of gaseous 4H‐pyran‐4‐thione were investigated using the CASSCF//TD‐B3LYP methods and group theory. Using the effective one‐electron spin‐orbit Hamiltonian, the strengths of spin‐orbit coupling were estimated, which plays an essential role in the spin transitions between different spin states. Calculated results show that phosphorescence and non‐radiative decay via intersystem crossing to the S0 state are concurrent processes occurring at the T1 state. A rapid depletion of the S1 state via intersystem crossing to the T1 state can be mediated by the T2 state, if spin relaxation is fast within the triplet levels. Our calculated results are in close agreement with experimental observations.
Selective Hydrogenation of Avermectin Catalyzed by Iridium‐Phosphine Complexes
Authors: MA Xiao‐Yan , WANG Kun , ZHANG Lei , LI Xian‐Jun , LI Rui‐Xiang
Published: October 2007

A series of new iridium complexes, IrCl(COD)(TMOPP) (1) [COD=1,5‐cyclooctadiene, TMOPP=tris(4‐ methoxyphenyl)phosphine], IrCl(COD)(TFMPP) (2) [TFMPP=tris(4‐trifluoromethylphenyl)phosphine], IrCl‐ (COD)(BDNA) (3) [BDNA=1,8‐bis(diphenylphosphinomethyl)naphthalene], IrCl(COD)(BISBI) (4) [BISBI=2,2′‐bis(diphenylphosphinomethyl)biphenyl] and IrCl(COD)(BDPB) (5) [BDPB=1,2‐bis(diphenylphosphinometh‐ yl)benzene], were synthesized and characterized by NMR spectra and elemental analyses. In order to obtain the relationships between complex structures and their catalytic properties, IrCl(COD)(DPPM) (6) [DPPM=bis(diphenylphosphino)methane], IrCl(COD)(DPPE) (7) [DPPE=1,2‐bis(diphenylphosphino)ethane], IrCl(COD)(DPPP) (8) [DPPP=1,3‐bis(diphenylphosphino)propane] and IrCl(COD)(TPP) (9) [TPP=triphenylphosphine], were also synthesized according to the reported methods. The hydrogenation results showed that the low electronic density at the central metal was favorable to increase the catalytic activity for the hydrogenation of avermectin, but decrease the selectivity to ivermectin. The complex with a large chelating ring and a bulky chelating backbone would easily cause the cleavage of CO bond in avermectin to give a byproduct avermectin aglycon.
Characterization, Crystal Structure and Initial DNA Binding Interaction of Two Cu(II) Complexes with 4,5‐Diazafluoren‐9‐one
Authors: SONG Yan‐Hong , ZHANG Rong‐Lan , SUN Qing‐Jin , XU Zhan‐Wei , GAO Quan‐Chang , LIU Hua‐Qiang , ZHAO Jian‐She
Published: October 2007

Two new complexes [Cu(dafo)2(en)](ClO4)2·2H2O (en=NH2CH2CH2NH2) 1 and [Cu(dafo)2(dap)](ClO4)2· 2H2O [dap=NH2CH2CH(CH3)NH2] 2 (dafo=4,5‐diazafluoren‐9‐one) have been synthesized and characterized by elemental analysis, IR and UV spectra. Meanwhile, the complex 1 has been characterized by single crystal X‐ray diffraction analysis. The initial DNA binding interactions of the complexes 1 and 2 have been investigated by UV spectra, emission spectra and cyclic voltammogram. Concluding the results of three methods used to measure the interaction of complexes 1 and 2 with DNA, the action mode of the two complexes with DNA is intercalation, and character of ligands and steric effect may affect the interaction of the complexes with DNA.
Effect of Variant Counterions on Stability and Particle Size of Silica Sol
Authors: PAN Ming‐Chu , YANG Yu‐Xiang , YING Hai‐Ping , JIA Xiang‐Chen , CHEN Ya‐Ru , TANG Yue
Published: October 2007

The effects of variant counterions with ionic strength of 0.05, 0.10, 0.20 and 0.25 mol·kg−1 on the stability and particle size of silica sols have been studied using the traditional methods of Ubbelohde viscosity measurement, TEM and titration respectively, finding that the stability and particle size of the silica sols are all concerned with the acidic, positively electric properties and the sizes of the counterions, as well as the attraction between the counterions and surface silicon hydroxyl groups of the silica sols. The small positively charged counterions lead to the decrease in particle sizes, making the silica sol the most stable. But the larger weakly acidic counterions can restrict the particle sizes of the silica sols and easily make the sols coagulate. It was also found that there existed a linear relationship between log r and log η, which has not ever been reported. The effect of temperature on the stability and particle sizes was also discussed.
A Sensitive Derivatization Method for the Determination of the Sugar Composition after Pre‐column Reductive Amination with 3‐Amino‐9‐ethylcarbazole (AEC) by High‐Performance Liquid Chromatography
Authors: ZHANG Ying , HUANG Lin‐Juan , WANG Zhong‐Fu
Published: October 2007

3‐Amino‐9‐ethylcarbazole (AEC) was employed for monosaccharide derivatization. The derivatives can be analyzed by high‐performance liquid chromatography (HPLC) with an ultraviolet detection (wavelength: 254 nm). Monosaccharides were quantitatively derivatized with 3‐amino‐9‐ethylcarbazole (AEC) at 70 °C for 60 min. The method was linear for all samples over the concentration range tested (r>0.999), the precision was found to be satisfactory (R.S.D.<3%), and the recovery ratios were >98.62%. The stability analysis showed R.S.D. was between 1.81% –3.16%. Detection limits for the samples (D‐glucose, L‐xylose, D‐mannose, L‐arabinose, and L‐rhamnose) ranged from 0.06 to 1.97 ng/mL (S/N=3). Under the optimized derivatization and HPLC conditions, five monosaccharides were well separated using a narrow bore C18 column (250 mm×4.6 mm) with 0.1 mol/L ammonium acetate containing 25% acetonitrile at a flow rate of 0.5 mL/min. As an application, the method has been successfully applied to the determination of monosaccharide compositions of three polysaccharides SPPA‐1, SPPB‐1 and SPPC‐1 of Spirulina platensis. This method also has potential application to oligosaccharide or glycan analyses.
Selective Electrochemical Recognition ofo‐Phenylenediol by a Novel Calix[4]arene Derivative
Authors: LÜ Jian‐Quan , ZHANG Hai‐Li , LU Ping
Published: October 2007

A new type of calixarene‐modified electrode has been prepared by directly coating the surface of a glassy carbon electrode with tetrahydrofuran solution containing 25,26,27,28‐tetra‐(3‐amidino thiopropoxy)‐5,11,17,23‐tetra‐tert‐butylcalix[4]arene, and applied to the investigation of electrochemical behavior of phenylenediols. The results showed that the modified electrode could selectively recognizeo‐phenylenediol, making the over‐potential ofo‐phenylenediol dropped and peak current increased greatly. The anodic peak current is proportional to the concentration ofo‐phenylenediol in the range of 1.0×10−5–1.0×10−4mol·L−1with the detection limit (S/N=3) of 1.0×10−7mol·L−1. The recognizing mechanism, including electrochemical process and binging sites, was also discussed using voltammetry.
Hydrolysis Reaction of N‐Phosphoryl‐α‐, β‐ and γ‐amino Acids Studied by HPLC
Authors: QIANG Li‐Ming , CAO Shu‐Xia , ZHAO Xiao‐Yang , LIU Ruo‐Yu , LIU Ji‐Hong , LU Jian‐Sha , ZHAO Yu‐Fen
Published: October 2007

The hydrolysis reactions of N‐(O,O′‐diisopropyl)phosphoryl‐L‐α‐alanine (DIPP‐L‐α‐Ala), N‐(O,O′‐diisopropyl)‐ phosphoryl‐D‐α‐alanine (DIPP‐D‐α‐Ala), N‐(O,O′‐diisopropyl)phosphoryl‐β‐alanine (DIPP‐β‐Ala) and N‐(O,O′‐ diisopropyl)phosphoryl‐γ‐amino butyric acid (DIPP‐γ‐Aba), were studied by HPLC and their hydrolysis reaction kinetic equations were obtained. Under acid conditions, the reaction rate of DIPP‐L‐α‐Ala was close to that of DIPP‐D‐α‐Ala and the same rule was true between DIPP‐β‐Ala and DIPP‐γ‐Aba. Meantime, the reaction rate of DIPP‐L/D‐α‐Ala was as 10 times as that of DIPP‐β‐Ala or DIPP‐γ‐Aba. Under basic conditions, the hydrolysis reactions of DIPP‐β‐Ala and DIPP‐γ‐Aba almost did not take place and the reaction rate of DIPP‐L/D‐α‐Ala was about 1/10 of that under acid conditions. Moreover, theoretical calculation further illuminated the differences of the hydrolysis rate from the view of energy. The results would provide some helpful clues to why nature chose α‐amino acids but not other kinds of analogs as protein backbones.
Synthesis and Biological Activities of Substituted Triazolethione Schiff Base
Authors: SUN Xiao‐Hong , TAO Yan , LIU Yuan‐Fa , CHEN Bang
Published: October 2007

Six novel Schiff bases have been synthesized by the condensation reaction of 4‐amino‐5‐(4‐pyridyl)‐2,4‐dihy‐ dro‐1,2,4‐triazole‐3‐thione with various benzaldehydes. The structures of the compounds have been confirmed by 1H NMR, IR and elemental analysis. The preliminary bioassay indicated that the title compounds possessed good fungicidal activities to several vegetable pathogens.
Electrochemical Reduction of 1,2‐Di(p‐tolylimino)ethane and 1,2‐Di(2,4‐dimethylphenylimino)ethane in Dimethylformamide
Authors: FOTOUHI Lida , ZEIENALI Mahbobeh , DEHGHANPOUR Saeed , NEMATOLLAHI Davood
Published: October 2007

1,2‐Di(p‐tolylimino)ethane (I) and 1,2‐Di(2,4‐dimethylphenylimino)ethane (II) were synthesized and their electrochemical behavior investigated in dimethylformamide using classical voltammetry, differential pulse voltammetry, cyclic voltammetry, chronoamperometry, controlled potential electrolysis and coulometry. Both bis‐Schiff base ligands examined show a cathodic irreversible peak which corresponds to one‐electron reduction of the substrate to form anion radical. According to the fact obtained from cyclic voltammetry, that the current function (ip/ù1/2) is a decreasing function of the scan rate, it can be concluded that there is a following coupling chemical reaction (EC mechanism). Thus, the most probable mechanism of electroreduction of both ligands is the coupling of two radicals to form a dimer.
Metallotricycle of Lanthanide Supported by a Bridging Diamide: Syntheses and Molecular Structures of {Li(THF)3[LnCl(μ2‐trans‐1,2‐(NSiMe3)2C6H10)(μ2‐Cl)]}2·2THF (Ln=Yb, Nd)
Authors: LU Cheng‐Rong , LI Hong‐Hai , ZHAO Bei , SHEN Qi , YAO Ying‐Ming , ZHANG Yong
Published: October 2007

The reactions of dilithium salt of trans‐1,2‐bis(trimethylsilylamino)cyclohexane with anhydrous lanthanide trichlorides LnCl3 (Ln=Yb, Nd) in THF afforded the dianionic binuclear tricycles of lanthanide chlorides {Li(THF)3[LnCl(µ2‐trans‐1,2‐(NSiMe3)2C6H10)((2‐Cl)]}2·2THF (Ln=Yb 1, Nd 2) in moderate yields. Both of the bridged complexes were characterized by elemental analysis, IR spectroscopy and single‐crystal X‐ray diffraction. Crystal structural analysis shows that the two complexes are the analogues which have a tricyclic framework built by two bridged lanthanide metals, four nitrogens and four carbons from two diamide ligands. Each lanthanide metal coordinates to three nitrogen atoms and two chlorines to form a distorted trigonal bipyramid and connects with a lithium by a bridging chlorine.
Chiral Salicyl Diamines: Potent Anticancer Molecules
Authors: Gao Jian , Liu Ya‐Guang , Zhou Yaqing , Zingaro Ralph A.
Published: October 2007

A set of 12 enantiomeric diamine‐based small molecules was synthesized and screened for anticancer activity against five human cancer cell lines: NCI‐H460, A549, MCF‐7, SK‐BR‐3, and T‐47D. The salicyl diamino compounds (1–6) were found to induce inhibition of the growth of cancer cells at submicromolar concentrations. The lead compound, N,N′‐bis‐salicyl‐(1R,2R)‐diaminocyclohexane (1) displayed single‐reagent anticancer activity with an IC50 value equal to or less than 2.0 μM in H460 and A‐549 cancer cells. SRB and colony formation assays indicated that compound 1 shows greater cytotoxic activity toward MCF‐7 cells than MCF‐10A cells. Real‐time RT‐PCR analysis demonstrated that compound 1, is an extremely efficient regulator of antiapoptotic genes, Bcl‐xL, Bcl‐2, and the cell cycle related gene, cyclin D1. This study provides a new insight into the development of novel small molecules in the treatment of human breast cancers.
Stereochemical and Steric Control of the UDP‐Glucuronosyltransferase‐Catalyzed Conjugation Reaction: A Rational Approach for the Design of Inhibitors for the Human UGT2B7
Authors: Bichlmaier Ingo , Finel Moshe , Sippl Wolfgang , Yli‐Kauhaluoma Jari
Published: October 2007

A set of 76 derivatives of the epimeric tricyclic sesquiterpenols longifolol and isolongifolol was subjected to inhibition and glucuronidation assays employing the human UDP‐glucuronosyltransferase (UGT) 2B7. Detailed structure–activity relationships (SARs) with respect to functionality, stereochemical properties, and steric features were derived. To gain further insight into the SARs of UGT2B7 ligands herein, we have developed a 3D‐quantitative structure–activity relationship (3D‐QSAR) using Comparative Molecular Similarity Analysis (CoMSIA). The formation of the enzyme–inhibitor complex was predominantly controlled by spatially directed hydrophobic interactions. The glucuronidation rate was significantly influenced by the steric demand of substituents in proximity of the nucleophilic hydroxy group. The glucuronidation of the compounds was prevented by the introduction of bulky substituents such as isopropyl, tert‐butyl, and phenyl groups. The epimeric longifolol derivatives of series D were the best inhibitors displaying IC50 values as low as 4.6 nM. This study shows that high‐potency substrates can be turned into potent inhibitors by addressing functional, stereochemical, and steric properties.
Dendritic PARACEST contrast agents for magnetic resonance imaging
Authors: Pikkemaat J.A. , Wegh R.T. , Lamerichs R. , van de Molengraaf R.A. , Langereis S. , Burdinski D. , Raymond A.Y.F. , Janssen H.M. , de Waal B.F.M. , Willard N.P. , Meijer E.W. , Grüll H.
Published: October 2007

MRI contrast agents based on chemical exchange‐dependent saturation transfer (CEST), such as Yb(III)DOTAM complexes, are highly suitable for pH mapping. In this paper, the synthesis of Yb(III)DOTAM‐functionalized poly(propylene imine) dendrimers is described. The applicability of these dendritic PARACEST MRI agents for pH mapping has been evaluated on a 7 T NMR spectrometer and on a 3 T clinical MRI scanner. As expected, based on the different numbers of exchangeable amide protons, the lowest detectable concentration of the first and third generation dendritic PARACEST agents is by a respective factor of about 4 and 16 lower than that of a mononuclear reference complex. The pH dependence of the CEST effect observed for these compounds depends on the generation of the poly(propylene imine) dendrimer. Upon going to higher generations of the Yb(III)DOTAM‐terminated dendrimer, a shift of the maximum CEST effect towards lower pH values was observed. This allows for a fine‐tuning of the responsive pH region by varying the dendritic framework. Copyright © 2007 John Wiley & Sons, Ltd.