bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical, angiographic, and intravascular ultrasound results of the VestSaync II trial
Authors: Costa J. Ribamar , Oliveira Breno A. , Abizaid Alexandre , Costa Ricardo , Perin Marco , Abizaid Andréa , Chamié Daniel , Fernando Tanajura Luiz , Sousa Amanda , Sousa J. Eduardo M.R.
Published: March 2013

Aim

We sought to assess the long term efficacy of the novel VESTAsync™ Eluting Stent (VES) combining a Cro‐Co platform with a nanothin‐microporous hydroxyapatite surface coating impregnated with a polymer‐free low‐dose of Sirolimus (55 μg).

Methods

The Vestasync II trial was a randomized (2:1), double‐blinded, multicenter comparison of the VES to its platform, the Gen X stent, with microporous hydroxyapatite surface coating without sirolimus. Patients were eligible if they presented de novo lesions in native coronary arteries with 3.0–3.5 mm diameter and ≤ 14 mm in length. Primary endpoint was 8‐month in‐stent late loss and % of stent obstruction. Lifelong aspirin and 6‐month clopidogrel were prescribed to all patients.

Results

Seventy‐five patients were enrolled (VES = 50 pts). Baseline characteristics included mean age of 58 years and 29% of diabetics. Reference vessel diameter and lesion length were 2.8 ± 0.4 mm and 13.0 ± 2.0 mm, respectively. In‐stent late loss (0.39 ± 0.20 vs. 0.74 ± 0.52, P = 0.03) and % of neointima hyperplasia (9.3 ± 6.6% vs. 17.6 ± 9.4%, P = 0.0016) were significantly reduced in the VES cohort. Up to 1 year, there was a single case of myocardial infarction and one target lesion revascularization (TLR) (2%) in the VES group while in the control cohort there were one TLR (4%) and one cardiac death (4%).

Conclusion

The VestSync II trial is a proof‐of‐concept study and demonstrates the sustained efficacy of this novel polymer‐free sirolimus drug‐eluting stents. A larger trial, with more complex lesions, clinical endpoints and longer FU period is warranted. © 2013 Wiley Periodicals, Inc.
Diffusion of Saccharides and Sugar Alcohol Sorbitol in Chitosan Membranes and Beads
Authors: Waluga T. , Scholl S.
Published: March 2013

Diffusion coefficients of different sugars and the sugar alcohol sorbitol have been determined by two different experimental setups: mass transfer through a flat membrane in a diffusion cell and effusion experiments with beads in a batch stirred vessel. Diffusion experiments show highly consistent data with low uncertainties and high regression coefficients, while effusion experiments suffer from larger experimental uncertainties. For the diffusion through a chitosan membrane at 25 °C, typically one‐third of the free molecular diffusion coefficient is found, whereas at 40 °C only one‐quarter of it is reached. The influence of molecular size, structure, and temperature on the transport properties is discussed in detail.
Upgrading of Simulated Syngas by Using a Nanoporous Silica Membrane Reactor
Authors: Wei L. , Kawamoto K.
Published: March 2013

The permeance properties of a nanoporous silica membrane were first evaluated in a laboratory‐scale porous silica membrane reactor (MR). The results indicated that CO, CO2, and N2 inhibited H2 permeation. Increased H2 permeability and selectivity were obtained when gas was transferred from the lumen side to the shell side. This was therefore selected as a suitable permeation direction. On this basis, upgrading of simulated syngas was experimentally investigated as a function of temperature (150 – 300 °C), feed pressure (up to 0.4 MPa), and gas hourly space velocity (GHSV), by using a nanoporous silica MR in the presence of a Cu/ZnO/Al2O3 catalyst. The CO conversion obtained with the MR was significantly higher than that with a packed‐bed reactor (PBR) and broke the thermodynamic equilibrium of a PBR at 275 – 300 °C and a GHSV of 2665 h–1. The use of a low GHSV and high feed pressure improved the CO conversion and led to the recovery of more H2.
Load–Collapse–Release Cascades of Amphiphilic Guest Molecules in Charged Dendronized Polymers through Spatial Separation of Noncovalent Forces
Authors: Kurzbach Dennis , Zhang Xiuqiang , Zhang Baozhong , Arnold Philipp , Hinderberger Dariush
Published: March 2013

The ability to pack guest molecules into charged dendronized polymers (denpols) and the possibility to release these guest molecules from subsequently densely aggregated denpols in a load–collapse–release cascade is described. Charged denpols, which constitute molecular objects with a persistent, well‐defined envelope and interior, are capable of incorporating large amounts of amphiphilic guest molecules. Simultaneously, multivalent ions can coordinate to the surfaces of charged denpols, leading to counterion‐induced aggregation of the already guest‐loaded host structures. Thus, although the local guest concentration in denpol‐based molecular transport might already be initially high due to the dense guest packing inside the dendritic denpol scaffolding, the “local” guest concentration can nonetheless be further increased by packing (through aggregation) of the host–guest complexes themselves. Subsequent release of guest compounds from densely aggregated dendronized polymers is then possible (e.g., through increasing the solution concentration of imidazolium‐based ions). Augmented with this release possibility, the concept of twofold packing of guests, firstly through hosting itself and secondly through aggregation of the hosts, gives rise to a load–collapse–release cascade that strikingly displays the high potential of dendronized macromolecules for future molecular transport applications.
CeO2‐Based Pd(Pt) Nanoparticles Grafted onto Fe3O4/Graphene: A General Self‐Assembly Approach To Fabricate Highly Efficient Catalysts with Magnetic Recyclable Capability
Authors: Wang Xiao , Liu Dapeng , Song Shuyan , Zhang Hongjie
Published: March 2013

New Pd(Pt) catalysts have been fabricated by assembling multicomponents of Fe3O4 and CeO2/Pd(Pt) on the surface of reduced graphene oxide (RGO) nanosheets in layers. The as‐obtained Pd(Pt) catalysts exhibit extremely high catalytic activity in the selective hydrogenation reaction of nitrobenzene. Owing to the presence of Fe3O4, the catalysts can be easily recycled from the catalytic system through magnetic separation. Their high activity, stability, and magnetic recyclability make the as‐obtained hybrids very promising as catalysts in catalytic applications. Compared to other traditional multishell magnetic catalysts that were prepared by means of layer‐by‐layer technology, our process is much more facile and more easily controlled.
ChemInform Abstract: Thermoelectric Properties of Tl10‐xLnxTe6 with Ln: Ce, Pr, Nd, Sm, Gd, Tb, Dy, Ho and Er, and (0.25 ≤ x ≤ 1,32).
Authors: Bangarigadu‐Sanasy Savitree , Sankar Cheriyedath Raj , Schlender Philipp , Kleinke Holger
Published: March 2013

The title materials are prepared from stoichiometric amounts of the elements (623 K for 24 h, 873 K for 48 h, 728 K for 7 d).
ChemInform Abstract: Nanocrystalline Fe83P16Cu1 Soft Magnetic Alloy Produced by Crystallization of Its Amorphous Precursor.
Authors: Chen F. G. , Wang Y. G. , Miao X. F. , Hong H. , Bi K.
Published: March 2013

The title alloy is prepared by melt‐spinning from mixtures of Fe, P—Fe alloy, and Cu in a high‐purity argon atmosphere followed by annealing at 563 K for 2 min.
ChemInform Abstract: Isoselenazolones as Catalysts for the Activation of Bromine: Bromolactonization of Alkenoic Acids and Oxidation of Alcohols.
Authors: Balkrishna Shah Jaimin , Prasad Ch. Durga , Panini Piyush , Detty Michael R. , Chopra Deepak , Kumar Sangit
Published: March 2013

The isoselenazolone (ISA) efficiently promotes bromolactonization of alkenoic acids, oxidation of secondary alcohols, as well as bromoesterification of alkenes and alkynes.Both processes proceed with good to high regio‐ and stereoselectivity.
ChemInform Abstract: Gold Meets Enamine Catalysis in the Enantioselective α‐Allylic Alkylation of Aldehydes with Alcohols.
Authors: Chiarucci Michel , di Lillo Marzia , Romaniello Alessandro , Cozzi Pier Giorgio , Cera Gianpiero , Bandini Marco
Published: March 2013

Synergetic Au(I)‐ and amine organo‐catalysis promotes intramolecular stereo‐ and enantioselective α‐allylic alkylations of aldehydes with simple primary and secondary alcohols.
ChemInform Abstract: Enantioselective Photooxygenation of β‐Keto Esters by Chiral Phase‐Transfer Catalysis Using Molecular Oxygen.
Authors: Lian Mingming , Li Zhi , Cai Yuanchun , Meng Qingwei , Gao Zhanxian
Published: March 2013

The reaction proceeds under mild conditions with good enantioselectivities and affords the corresponding hydroxylation products in good yields.
ChemInform Abstract: A Modular Synthesis of Polysubstituted Indolizines.
Authors: Kucukdisli Murat , Opatz Till
Published: March 2013

Title compounds are synthesized by [3 + 2] cycloaddition of nitroalkenes (IV) with pyridinium salts.
ChemInform Abstract: An Efficient, Soluble, and Recyclable Multiwalled Carbon Nanotubes‐Supported TEMPO for Oxidation of Alcohols.
Authors: Wang Yiming , Song Xiaoyu , Shao Songhai , Zhong Hongmin , Lin Fei
Published: March 2013

The title catalyst combines positive aspects of solid as well as soluble supports, e.g., homogeneous dispersion in the reaction medium, easy recovery, solution‐based characterization, and a catalytic activity superior to heterogeneous catalysis.
ChemInform Abstract: Ruthenium Nanoparticles‐Catalyzed, Controlled and Chemoselective Hydrogenation of Nitroarenes Using Ethanol as a Hydrogen Source.
Authors: Kim Ju Hyun , Park Ji Hoon , Chung Young Keun , Park Kang Hyun
Published: March 2013

In the synthesis of azoxybenzenes (II) the catalyst can be recycled and reused for at least four times with only a slight drop in yield.
ChemInform Abstract: A Mild, Palladium‐Catalyzed Method for the Dehydrohalogenation of Alkyl Bromides: Synthetic and Mechanistic Studies.
Authors: Bissember Alex C. , Levina Anna , Fu Gregory C.
Published: March 2013

The elimination from functionalized aliphatic organic halides is studied in the presence of base and a Pd‐phosphine catalyst.
ChemInform Abstract: Palladium(II)‐Catalyzed Hydration of Alkynylphosphonates to β‐Ketophosphonates.
Authors: Li Xiubin , Hu Gaobo , Luo Ping , Tang Guo , Gao Yuxing , Xu Pengxiang , Zhao Yufen
Published: March 2013

An efficient protocol for the title reaction without additional co‐catalysts is developed.
ChemInform Abstract: InCl3‐Catalyzed Synthesis of 1,2‐Dimetallic Compounds by Direct Insertion of Aluminum or Zinc Powder.
Authors: Bluemke Tobias D. , Klatt Thomas , Koszinowski Konrad , Knochel Paul
Published: March 2013

Conversion of aromatic 1,2‐dibromides or analogous 1‐bromo‐2‐triflates into 1,2‐dimetallic species, which can be isolated, is dramatically improved by catalytic amounts of InCl3.
ChemInform Abstract: Secondary Amine‐Catalyzed Asymmetric γ‐Alkylation of α‐Branched Enals via Dienamine Activation.
Authors: Silvi Mattia , Cassani Carlo , Moran Antonio , Melchiorre Paolo
Published: March 2013

In the case of products (XIII), each diastereomer has an e.e.
ChemInform Abstract: Ruthenium Pincer‐Catalyzed Cross‐Dehydrogenative Coupling of Primary Alcohols with Secondary Alcohols under Neutral Conditions.
Authors: Srimani Dipankar , Balaraman Ekambaram , Gnanaprasam Boopathy , Ben‐David Yehoshoa , Milstein David
Published: March 2013

It is crucial to use an excess of the secondary alcohols to achieve the high yields of the esters.
ChemInform Abstract: Facially Selective Cu‐Catalyzed Carbozincation of Cyclopropenes Using Arylzinc Reagents Formed by Sequential I/Mg/Zn Exchange.
Authors: Tarwade Vinod , Selvaraj Ramajeyam , Fox Joseph M.
Published: March 2013

In the presence of CuCN, various functionalized arylzinc compounds generated in situ undergo convenient and stereoselective coupling with the cyclopropene (II) to afford cis‐substituted derivatives.
ChemInform Abstract: Copper‐Catalyzed Decarboxylative Alkenylation of sp3 C—H Bonds with Cinnamic Acids via a Radical Process.
Authors: Cui Zili , Shang Xiaojie , Shao Xiang‐Feng , Liu Zhong‐Quan
Published: March 2013

The coupling of aryl‐substituted acrylic acids with alcohols, ethers, and hydrocarbons provides a useful method for the stereospecific synthesis of substituted (E)‐alkenes (33 examples).
ChemInform Abstract: Enantioselective Zinc‐Mediated Conjugate Addition of Terminal Alkynes to Enones.
Authors: Blay Gonzalo , Cardona Luz , Pedro Jose R. , Sanz‐Marco Amparo
Published: March 2013

The reaction uses a catalytic amount of a chiral ligand to induce enantioselectivity.
ChemInform Abstract: Copper Complex of Aminoisoborneol Schiff Base Cu2(SBAIB‐d)2: An Efficient Catalyst for Direct Catalytic Asymmetric Nitroaldol (Henry) Reaction.
Authors: Boobalan Ramalingam , Lee Gene‐Hsian , Chen Chinpiao
Published: March 2013

The reaction with nitromethane is applicable to a wide range of aromatic [cf.
ChemInform Abstract: Pyrrolidine‐thioxotetrahydropyrimidinone as an Efficient Organocatalyst for the Enantioselective Michael Addition of Cyclic Ketones to Nitrodienes.
Authors: Tsakos Michail , Trifonidou Maria , Kokotos Christoforos G.
Published: March 2013

Excellent diastereoselectivities (crude mixtures) and enantioselectivities are achieved when cyclohexanone is used as the substrate.
ChemInform Abstract: Highly Efficient and Selective Hydrogenation of Unsaturated Carbonyl Compounds Using Ni—Sn Alloy Catalysts.
Authors: Rodiansono Rodiansono , Khairi Syahrul , Hara Takayoshi , Ichikuni Nobuyuki , Shimazu Shogo
Published: March 2013

The best results are obtained using a supported Ni—Sn(1.5)/TiO2 catalyst.
ChemInform Abstract: Bromodimethylsulfonium Bromide as a Potential Candidate for Photocatalytic Selective Oxidation of Benzylic Alcohols Using Oxygen and Visible Light.
Authors: Gazi Sarifuddin , Ananthakrishnan Rajakumar
Published: March 2013

The catalytic photooxidation of benzylic alcohols by molecular oxygen under irradiation with a household compact fluorescent lamp is highly selective and affords the corresponding carbonyl compound in good to excellent yields.
ChemInform Abstract: Synthesis of N1,N3‐Disubstituted Formamidrazones via the TMSCI‐Promoted Reaction of Isocyanides with Thiosemicarbazones.
Authors: Sarnpitak Pakornwit , Tsirulnikov Sergey , Krasavin Mikhail
Published: March 2013

The new Tms‐Cl‐promoted reaction of thiosemicarbazones with isocyanides provides access to diversely substituted formamidrazones.
ChemInform Abstract: Rhodium—Phosphoramidite‐Catalyzed Alkene Hydroacylation: Mechanism and Octaketide Natural Product Synthesis.
Authors: von Delius Max , Le Christine M. , Dong Vy M.
Published: March 2013

The efficient method shows a good to excellent selectivity for linear products.
ChemInform Abstract: Asymmetric Catalytic Hydrogenation for Large‐Scale Preparation of Optically Active 2‐(N‐Benzoylamino)cyclohexanecarboxylic Acid Derivatives.
Authors: Kajiwara Takeshi , Konishi Takahiro , Yamano Mitsuhisa
Published: March 2013

Optimal conditions are developed for the asymmetric hydrogenation of ester (II).
ChemInform Abstract: Iodobenzene Diacetate (PIDA)/Zn(II)‐Mediated Oxidation and Cleavage of C—C Bond: Formation of Substituted N‐Aryl Carbamoyl Methyl Diacetates and Derivatives from 3‐Oxo‐butanamides.
Authors: Wenjun Hu , Zhaohui Deng , Chen Cui , Liu Wei‐Bing
Published: March 2013

A mechanistic proposal for this novel transformation involving both C—O bond formation and C—C bond cleavage is given.
ChemInform Abstract: Asymmetric Counteranion‐Directed Iron Catalysis: A Highly Enantioselective Sulfoxidation.
Authors: Liao Saihu , List Benjamin
Published: March 2013

The new sulfoxidation catalyst IAB consisting of an achiral iron(III)‐salen cation and a chiral phosphate counteranion is used for the oxidation of various sulfides (I) to afford the corresponding sulfoxides ((R)‐II) with high yields and enantioselectivities.
ChemInform Abstract: A Recyclable Magnetic Nanoparticles Supported Palladium Catalyst for the Hiyama Reaction of Aryltrialkoxysilanes with Aryl Halides.
Authors: Zhang Lei , Li Pinhua , Li Hongji , Wang Lei
Published: March 2013

A wide range of aryl iodides and bromides is applied in the reaction with phenyl trimethyloxy‐ or triethyloxysilanes to afford biaryl derivatives in high yields.
ChemInform Abstract: Effective Palladium‐Catalyzed Synthesis of Triarylethene‐Based Molecules in Aqueous Solution.
Authors: Zhu Yan , Sun Peng , Yang Hailong , Lu Linhua , Yan Hong , Creus Marc , Mao Jincheng
Published: March 2013

The one‐step double Suzuki—Miyaura coupling reaction of 2‐aryl‐1,1‐dibromo‐1‐alkenes with aryl/heteroarylboronic acids proceeds under ligand‐, additive‐, and inert‐gas‐free conditions using aqueous PEG as solvent.
ChemInform Abstract: Crossed Intermolecular [2 + 2] Cycloaddition of Styrenes by Visible Light Photocatalysis.
Authors: Ischay Michael A. , Ament Michael S. , Yoon Tehshik P.
Published: March 2013

A highly efficient method for the chemoselective radical‐cation mediated crossed [2 + 2] cycloaddition of styrenes, affording unsymmetrically substituted cyclobutanes in a diastereoselective fashion, is reported.
ChemInform Abstract: Regioselective Cyclizations Utilizing a Gold‐Catalyzed [3,3] Propargyl Ester Rearrangement.
Authors: Cran John W. , Krafft Marie E.
Published: March 2013

A concise strategy for the regioselective synthesis of unsaturated carbocycles is demonstrated.
ChemInform Abstract: Expeditious Synthesis of Tetrasubstituted Helical Alkenes by a Cascade of Palladium‐Catalyzed C—H Activations.
Authors: Liu Hongqiang , El‐Salfiti Mohamed , Lautens Mark
Published: March 2013

A highly effective synthesis of sterically crowded target compounds is developed through a Pd‐catalyzed norbornene‐mediated reaction of alkyne substrates with iodoarenes.
ChemInform Abstract: Ionic Liquid 1,3‐Disulfonic Acid Imidazolium Hydrogen Sulfate: A Novel and Highly Efficient Catalyst for the Preparation of 1‐Carbamatoalkyl‐2‐naphthols and 1‐Amidoalkyl‐2‐naphthols.
Authors: Zare Abdolkarim , Yousofi Tahereh , Moosavi‐Zare Ahmad Reza
Published: March 2013

The title compounds (16 examples) are prepared in short reaction times (≤ 35 min) and without a solvent by the multicomponent reaction of β‐naphthol, benzaldehydes, and either carbamates or amides.
ChemInform Abstract: A Prototype Continuous‐Flow Liquid—Liquid Extraction System Using Open‐Source Technology.
Authors: O'Brien Matthew , Koos Peter , Browne Duncan L. , Ley Steven V.
Published: March 2013

A computer control script is used to monitor three different reactions in a liquid flow reactor via a simple webcam setup.
ChemInform Abstract: Asymmetric Hydrogenation of Thiophenes and Benzothiophenes.
Authors: Urban Slawomir , Beiring Bernhard , Ortega Nuria , Paul Daniel , Glorius Frank
Published: March 2013

Various thiophene substrates are subjected to optimized conditions A), where high enantioselectivities are obtained in some cases.
ChemInform Abstract: Preparation of Brominated 2‐Alkoxythiophenes via Oxidation and Etherification of 2‐Thienyltrifluoroborate Salts.
Authors: Tietz Jonathan I. , Seed Alexander J. , Sampson Paul
Published: March 2013

The thienones (IIa) and (IIb) are air‐sensitive liquids which decompose even on storage in a freezer.
ChemInform Abstract: Quadri‐Synergetic Effect for Highly Effective Carbon Dioxide Fixation and Its Application to Indoloquinolinone.
Authors: Li Suhua , Ma Shengming
Published: March 2013

The use of ZnMe2 as a promoter and the amounts of ZnMe2, CsF and catalyst are crucial for the yields of the products.
ChemInform Abstract: Copper‐Catalyzed Desymmetric Intramolecular Ullmann C—N Coupling: An Enantioselective Preparation of Indolines.
Authors: Zhou Fengtao , Guo Jiajia , Liu Jianguang , Ding Ke , Yu Shouyun , Cai Qian
Published: March 2013

The first highly enantioselective protocol for preparation of indolines and tetrahydroquinolines via Cu‐catalyzed asymmetric desymmetrization of 2‐propanamines and 3‐pentaneamines, respectively is presented.
ChemInform Abstract: Synthesis of Cyclic α‐Hydrazino Acids.
Authors: Duttagupta Indranil , Goswami Koushik , Sinha Surajit
Published: March 2013

Starting from readily available raw materials, novel approaches toward the synthesis of title compounds with 5‐ to 9‐membered ring size are developed.
ChemInform Abstract: Synthesis of Tri‐ and Tetrasubstituted Pyrazoles via Ru(II) Catalysis: Intramolecular Aerobic Oxidative C—N Coupling.
Authors: Hu Jiantao , Chen Shi , Sun Yonghui , Yang Jing , Rao Yu
Published: March 2013

The method provides a broad spectrum of target compounds including the nonsteroidal anti‐inflammatory drug celebrex (XXIIa) and some derivatives.
ChemInform Abstract: Synthesis of Enantiomerically Enriched Imidazolidin‐2‐ones Through Asymmetric Palladium‐Catalyzed Alkene Carboamination Reactions.
Authors: Hopkins Brett A. , Wolfe John P.
Published: March 2013

Substrate electron effects and additives greatly affect the levels of asymmetric induction in the reactions of N‐allyl urea substrates with aryl bromides.
ChemInform Abstract: Novel and Green Protocol for the Synthesis of 2‐Iminohydantoins.
Authors: Kumar Vinod , Rana Hemlata , Kaushik M. P.
Published: March 2013

Treatment of aminoester substrates with aqueous NH3 at room temperature renders possible the access to a library of title compounds whose structure includes an amide and a guanidine functionality.
ChemInform Abstract: Cationic Bromonium Complex: NBS/P(O‐Ph)3 as an Efficient Catalyst for Nazarov Cyclization.
Authors: Guo Fenglou , Wang Limin , Mao Song , Zhang Chi , Yu Jianjun , Han Jianwei
Published: March 2013

The optimized conditions A) produce the desired target ring system with excellent diastereocontrol.
ChemInform Abstract: Self‐Buffering Hybrid Gold‐Polyoxometalate Catalysts for the Catalytic Cyclization of Acid‐Sensitive Substrates.
Authors: Dupre Nathalie , Brazel Christian , Fensterbank Louis , Malacria Max , Thorimbert Serge , Hasenkopf Bernold , Lacote Emmanuel
Published: March 2013

This method is particularly useful for the cycloisomerization of allenols, which are sensitive to dehydration, e.
ChemInform Abstract: Cyclotrimerization of Unsymmetrically Bromo‐Substituted Diynes: Toward the Synthesis of Potential Selective Inhibitors of Tyrosine Kinase 2.
Authors: Melnes Silje , Bayer Annette , Gautun Odd Reidar
Published: March 2013

The process is examined in the presence of Rh‐ and Ru‐catalysts concerning the formation of benzopyran and benzofuran derivatives.
ChemInform Abstract: One‐Pot Three‐Component Synthesis of 3‐Nitro‐2‐arylimidazo[1,2‐a]pyridine Derivatives Using Air as an Oxidant.
Authors: Yan Hao , Yan Rulong , Yang Sizhuo , Gao Xiai , Wang Yuling , Huang Guosheng , Liang Yongmin
Published: March 2013

A simple, environmentally friendly, and sustainable method for the synthesis of 3‐nitro‐2‐arylimidazo[1,2‐a]pyridine derivatives in moderate to good yields is presented.
ChemInform Abstract: Novel Syntheses of Pyrrolo[2,1‐a]isoquinolines via 1,3‐Dipolar Cycloaddition Between Isoquinoliniums and Alkynes.
Authors: Shang Yongjia , Wang Lifen , He Xinwei , Zhang Min
Published: March 2013

An efficient general method for the synthesis of pyrrolo[2,1‐a]isoquinolines (22 examples) is presented.
ChemInform Abstract: Facile Approach to Diverse 3‐Acylated Indolizines via a Sequential Sonogashira Coupling/Iodocyclization Process.
Authors: Jung Youngeun , Kim Ikyon
Published: March 2013

The convenient two‐step synthesis starting from esters (I) and (V) or nitrile (IX) allows an easy access to a broad spectrum of pharmaceutically interesting title compounds.
ChemInform Abstract: [5C + 1N] Annulations: Two Novel Routes to Substituted Dihydrofuro[3,2‐c]pyridines.
Authors: Huang Peng , Zhang Rui , Liang Yongjiu , Dong Dewen
Published: March 2013

In both cases, NH4OAc as the ammonia source is inserted via intermolecular addition on the carbon—carbon double bond.
ChemInform Abstract: An Approach to Alicyclic Ring‐Fused Xanthines.
Authors: Liubchak Kostiantyn , Tolmachev Andrey , Grygorenko Oleksandr O. , Nazarenko Kostiantyn
Published: March 2013

A convenient three‐step sequence allows the synthesis of the title compounds (V), which are of interest in drug discovery, via reaction of 6‐aminouracils with lactam derivatives (II), bromination, and copper‐catalyzed arylation.
ChemInform Abstract: Synthesis of Bicyclic 2,6‐Diketopiperazines via a Three‐Step Sequence Involving and Ugi Five‐Center, Four‐Component Reaction.
Authors: Dawidowski Maciej , Herold Franciszek , Wilczek Marcin , Turlo Jadwiga , Chodkowski Andrzej , Gomolka Anna , Kleps Jerzy
Published: March 2013

The target compounds are required in connection with a research on bicyclic title compounds of high anticonvulsant activity.
ChemInform Abstract: Rhodium‐Catalyzed Three‐Component Cross‐Addition of Silylacetylenes, Alkynyl Esters, and Electron‐Deficient Alkenes or Isocyanates.
Authors: Hoshino Yuki , Shibata Yu , Tanaka Ken
Published: March 2013

The unprecedented presented reaction is chemo‐, regio‐, and stereoselective.
ChemInform Abstract: Halide Effects on Cyclopropenium Cation Promoted Glycosylation with Deoxy Sugars: Highly α‐Selective Glycosylations Using a 3,3‐Dibromo‐1,2‐diphenylcyclopropene Promoter.
Authors: Nogueira Jason M. , Issa John Paul , Chu An‐Hsiang Adam , Sisel Jordan A. , Schum Ryan S. , Bennett Clay S.
Published: March 2013

α‐Selective dehydrative glycosylations of 2‐deoxy sugar donors are achieved using a new cyclopropenium cation promoter system.
ChemInform Abstract: Diastereoselective Multicomponent Reaction in Water: Synthesis of 2‐Azapyrrolizidine Alkaloid Analogues.
Authors: Rajarathinam Balakrishnan , Vasuki Gnanasambandam
Published: March 2013

The reaction is highly regio‐ and chemoselective and only one diastereomer is formed (24 examples).
ChemInform Abstract: Peroxynitrous Acid: Controversy and Consensus Surrounding an Enigmatic Oxidant
Authors: Koppenol Willem H. , Bounds Patricia L. , Nauser Thomas , Kissner Reinhard , Rueegger Heinz
Published: March 2013

Review: 121 refs.
ChemInform Abstract: Ordering and Magnetostriction in Fe Alloy Single Crystals
Authors: Guruswamy S. , Garside G. , Ren C. , Saha B. , Ramanathan M.
Published: March 2013

Review: 68 refs.
ChemInform Abstract: Mechanisms and Energies of Water Gas Shift Reaction on Fe‐, Co‐, and Ni‐Promoted MoS2 Catalysts
Authors: Chen Yan‐Yan , Dong Mei , Wang Jianguo , Jiao Haijun
Published: March 2013

Review: 60 refs.
ChemInform Abstract: Recent Progress in Developing Magnetic Properties of Mn‐Doped ZnO Diluted Magnetic Semiconductors
Authors: Zhang Yu , Li Tong , Wang Yaxin , Zhao Xinwei
Published: March 2013

Review: 22 refs.
ChemInform Abstract: Cation—Anion Palladium Complexes: The Effect of the Hydrogen Bond Character on Their Stability and Biological Activity
Authors: Efimenko I. A. , Shishilov O. N.
Published: March 2013

Review: 71 refs.
ChemInform Abstract: Synthesis and Applications of Disubstituted [2.2]Paracyclophanes
Authors: David Olivier R. P.
Published: March 2013

Review: 115 refs.
ChemInform Abstract: Recent Advances in Kumada—Tamao—Corriu Cross‐Coupling Reaction Catalyzed by Different Ligands
Authors: Heravi Majid M. , Hajiabbasi Parvin
Published: March 2013

Review: 67 refs.
ChemInform Abstract: Commercial Metal—Organic Frameworks as Heterogeneous Catalysts
Authors: Dhakshinamoorthy Amarajothi , Alvaro Mercedes , Garcia Hermenegildo
Published: March 2013

Review: 101 refs.
ChemInform Abstract: Immobilized Functional Ionic Liquids: Efficient, Green, and Reusable Catalysts
Authors: Li Hu , Bhadury Pinaki S. , Song Baoan , Yang Song
Published: March 2013

Review: 205 refs.
ChemInform Abstract: Synthesis of Pyrimidines
Authors: Verma H. , Basavaraja H. S. , Sharma V.
Published: March 2013

Review: 15 refs.
ChemInform Abstract: Phthalocyanines, Porphycenes, and Corroles: Nonlinear Optical Properties and Ultrafast Dynamics
Authors: Venugopal Rao S.
Published: March 2013

Review: 49 refs.
ChemInform Abstract: Copper‐Catalyzed sp3 C—H Amination
Authors: Gephart Raymond T. , Warren Timothy H.
Published: March 2013

Review: 200 refs.
ChemInform Abstract: 2‐Azapurine Nucleosides: Synthesis, Properties, and Base Pairing of Oligonucleotides
Authors: Budow Simone , Seela Frank
Published: March 2013

Review: 198 refs.
ChemInform Abstract: Hydrogenation of Ecdysteroids
Authors: Savchenko Rimma G. , Odinokov Victor N.
Published: March 2013

Review: 21 refs.
ChemInform Abstract: Dithiocarbamate Salts: Biological Activity, Preparation, and Utility in Organic Synthesis
Authors: Aly Ashraf A. , Brown Alan B. , Bedair Tarek M. I. , Ishak Esam A.
Published: March 2013

Review: 63 refs.
ChemInform Abstract: Pd/TOMPP‐Catalyzed Telomerization of 1,3‐Butadiene: From Biomass‐Based Substrates to New Mechanistic Insights
Authors: Hausoul Peter J. C. , Bruijnincx Pieter C. A. , Weckhuysen Bert M. , Gebbink Robert J. M. Klein
Published: March 2013

Review: 56 refs.
ChemInform Abstract: Radicals and Radical Ions as Intermediates of Electron Transfer Processes Through Peptides
Authors: Giese Bernd , Eckhardt Sonja , Lauz Miriam , Gao Jian , Wang Min
Published: March 2013

Review: 32 refs.
ChemInform Abstract: Ionic Interactions in Supramolecular Complexes
Authors: Schneider Hans‐Joerg
Published: March 2013

Review: 39 refs.
ChemInform Abstract: Chemical Methods to Interrogate Bacterial Quorum Sensing Pathways
Authors: Praneenararat Thanit , Palmer Andrew G. , Blackwell Helen E.
Published: March 2013

Review: 101 refs.
ChemInform Abstract: Critical Factors Affecting Oxygen Permeation Through Dual‐Phase Membranes
Authors: Zhu Xuefeng , Yang Weishen
Published: March 2013

Review: 52 refs.
ChemInform Abstract: Treatment of Mezcal Vinasses
Authors: Robles‐Gonzalez Vania , Galindez‐Mayer Juvencio , Rinderknecht‐Seijas Noemi , Poggi‐Varaldo Hector M.
Published: March 2013

Review: 200 refs.
ChemInform Abstract: Physical Methods and Techniques: NMR Spectroscopy
Authors: Edgar Mark
Published: March 2013

Review: 134 refs.
Holdup and Pressure Drop in Micro Packed‐Bed Reactors for Fischer‐Tropsch Synthesis
Authors: Knobloch Carsten , Güttel Robert , Turek Thomas
Published: March 2013

Low‐temperature Fischer‐Tropsch synthesis was investigated in micro packed‐bed reactors. Co/Re/γ‐Al2O3 catalysts with different particle shapes and sizes (60 to 580 μm) were employed. Tubular reactor geometry with lengths of up to 1 m was chosen. Pressure drop measurements in the absence of reaction and during reaction were carried out. For analysis of the experimental data a reactor model was developed, which was also used for the determination of liquid holdup. It could be observed that the liquid holdup is independent of conversion, reaction temperature, C5+ productivity, and reaction rate. For irregularly shaped catalyst particles, a liquid holdup in the range of 3 % was observed.
Development of a Reactor for Standardized Quantification of the Photocatalytic Hydrogen Production
Authors: Schwarze Michael , Schröder Marc , Stellmach Diana , Kailasam Kamalakannan , Thomas Arne , Schomäcker Reinhard
Published: March 2013

Die photokataytische Wasserspaltung mit Sonnenlicht gilt als eine der Traumreaktionen zur nachhaltigen Erzeugung von Wasserstoff. In Kombination mit einer Brennstoffzelle könnte auf diese Weise eine grüne Energieversorgung sichergestellt werden. Um geeignete Kandidaten für die Wasserspaltung zu identifizieren, müssen die Halbreaktion im Einzelnen unter definierten Bedingungen untersucht werden. Dabei sollten Versuchsbedingungen gewählt werden, die auch in der Realität wiedergefunden werden können. In diesem Beitrag wird ein Versuchsaufbau für die Quantifizierung der Photokatalyse vorgestellt und an mesoporösem Kohlenstoffnitrid als Photokatalysator erprobt. Die Wasserstoffentwicklungsrate wird mit einem Referenzsystem aus Photovoltaik und Elektrolyse verglichen und für den Entwurf eines Prototypen genutzt.
Wind and Coal: The Technical Photosynthesis
Authors: Effenberger Franz X. , Offermanns Heribert
Published: March 2013

Der steigende Energiebedarf und der damit verbundene CO2‐Ausstoß bei gleichzeitig abnehmenden Reserven an fossilen Rohstoffen erfordert neue Konzepte zur nachhaltigen Energieerzeugung. Das sogenannte Adam‐und‐Eva‐Prinzip zur CO2‐freien Gewinnung von Methanol aus Kohle und durch Nuklearenergie wird aufgegriffen und an heutige Gegebenheiten adaptiert. Als H2‐Quelle dient die Wasserelektrolyse mit Strom aus erneuerbaren Energien. Gleichzeitig wird mit dem bei der Elektrolyse gebildeten Sauerstoff in einem Oxyfuel‐Prozess Kohle verbrannt, dadurch Strom erzeugt und relativ reines CO2 erhalten. Dieses wird mit dem Elektrolyse‐Wasserstoff zu Methanol umgesetzt, das dann als Chemie‐ und Energierohstoff eingesetzt werden kann.
Alting barriers: synchronisation with choice in Java using JCSP
Authors: Welch Peter , Brown Neil , Moores James , Chalmers Kevin , Sputh Bernhard
Published: March 2013

Communicating Sequential Processes for Java (JCSP) is a mature library that implements CSP‐derived concurrency primitives in Java. A JCSP system is a hierarchical network of autonomous processes communicating over synchronous (optionally buffered) channels, and multiway synchronising through barriers. This paper presents a significant extension to the barrier mechanism: the fast resolution of choice between any number of barrier events, channel communications (in either direction) and timeouts. Previously, and in line with all currently released libraries and languages offering the CSP concurrency model, choice was restricted to channel inputs and timeouts. The paper demonstrates an application of alting barriers and explains the mechanisms used in their implementation that enables their use as guards in a choice. It also shows how choice over channel outputs becomes possible, as a simple consequence of having choice over barriers. Finally, an efficient implementation of CSP's broadcasting channels is presented (using a phased barrier synchronisation pattern) and a mechanism for allowing choice over these is discussed. With this extended JCSP, almost all CSP‐specified systems can now be directly implemented. The new library is available under LGPL open source. Copyright © 2010 PH Welch, NCC Brown, J Moores, KV Chalmers & B Sputh.
Adaptive workflow scheduling for dynamic grid and cloud computing environment
Authors: Rahman Mustafizur , Hassan Rafiul , Ranjan Rajiv , Buyya Rajkumar
Published: March 2013

Effective scheduling is a key concern for the execution of performance‐driven grid applications such as workflows. In this paper, we first define the workflow scheduling problem and describe the existing heuristic‐based and metaheuristic‐based workflow scheduling strategies in grids. Then, we propose a dynamic critical‐path‐based adaptive workflow scheduling algorithm for grids, which determines efficient mapping of workflow tasks to grid resources dynamically by calculating the critical path in the workflow task graph at every step. Using simulation, we compared the performance of the proposed approach with the existing approaches, discussed in this paper for different types and sizes of workflows. The results demonstrate that the heuristic‐based scheduling techniques can adapt to the dynamic nature of resource and avoid performance degradation in dynamically changing grid environments. Finally, we outline a hybrid heuristic combining the features of the proposed adaptive scheduling technique with metaheuristics for optimizing execution cost and time as well as meeting the users requirements to efficiently manage the dynamism and heterogeneity of the hybrid cloud environment. Copyright © 2013 John Wiley & Sons, Ltd.
Synthesis of CuCorePtShell Nanoparticles as Model Structures for Core–Shell Electrocatalysts by Direct Platinum Electrodeposition on Copper
Authors: Kulp Christian , Gillmeister Konrad , Widdra Wolf , Bron Michael
Published: March 2013

The synthesis of Cu(core)Pt(shell) model catalysts by the direct electrochemical deposition of Pt on Cu particles is presented. Cu particles with an average diameter of 200 nm have been deposited on glassy‐carbon electrodes by double pulse electrodeposition from a copper sulfate solution. Subsequent deposition from a platinum nitrate solution under potential control allows for a high selectivity of the Pt deposition towards Cu. Using a combination of cyclic voltammetry, XPS and sputtering, the structure of the generated particles has been analyzed and their core–shell configuration proven. It is shown that the electrocatalytic activity for the oxygen reduction is similar to that of other PtCu catalyst systems. The synthesized structures could allow for the analysis of structure–activity relations of core–shell catalysts on the way to the simple and controlled synthesis of supported Cu(core)Pt(shell) nanoparticles as oxygen reduction catalysts.
Modeling Diffusion in Foamed Polymer Nanocomposites
Authors: Ippalapalli Sandeep , Ranaprathapan A. Dileep , Singh Sachchida N. , Harikrishnan G.
Published: March 2013

Two‐way multicomponent diffusion processes in polymeric nanocomposite foams, where the condensed phase is nanoscopically reinforced with impermeable fillers, are investigated. The diffusion process involves simultaneous outward permeation of the components of the dispersed gas phase and inward diffusion of atmospheric air. The transient variation in thermal conductivity of foam is used as the macroscopic property to track the compositional variations of the dispersed gases due to the diffusion process. In the continuum approach adopted, the unsteady‐state diffusion process is combined with tortuosity theory. The simulations conducted at ambient temperature reveal distinct regimes of diffusion processes in the nanocomposite foams owing to the reduction in the gas‐transport rate induced by nanofillers. Simulations at a higher temperature are also conducted and the predictions are compared with experimentally determined thermal conductivities under accelerated diffusion conditions for polyurethane foams reinforced with clay nanoplatelets of varying individual lamellar dimensions. Intermittent measurements of foam thermal conductivity are performed while the accelerated diffusion proceeded. The predictions under accelerated diffusion conditions show good agreement with experimentally measured thermal conductivities for nanocomposite foams reinforced with low and medium aspect‐ratios fillers. The model shows higher deviations for foams with fillers that have a high aspect ratio.
Effect of Hydrogen on O2 Adsorption and Dissociation on a TiO2 Anatase (001) Surface
Authors: Liu Liangliang , Wang Zhu , Pan Chunxu , Xiao Wei , Cho Kyeongjae
Published: March 2013

The effect of hydrogen on the adsorption and dissociation of the oxygen molecule on a TiO2 anatase (001) surface is studied by first‐principles calculations coupled with the nudged elastic band (NEB) method. Hydrogen adatoms on the surface can increase the absolute value of the adsorption energy of the oxygen molecule. A single H adatom on an anatase (001) surface can lower dramatically the dissociation barrier of the oxygen molecule. The adsorption energy of an O2 molecule is high enough to break the OO bond. The system energy is lowered after dissociation. If two H adatoms are together on the surface, an oxygen molecule can be also strongly adsorbed, and the adsorption energy is high enough to break the OO bond. However, the system energy increases after dissociation. Because dissociation of the oxygen molecule on a hydrogenated anatase (001) surface is more efficient, and the oxygen adatoms on the anatase surface can be used to oxidize other adsorbed toxic small gas molecules, hydrogenated anatase is a promising catalyst candidate.
Supramolecular Cl⋅⋅⋅H and O⋅⋅⋅H Interactions in Self‐Assembled 1,5‐Dichloroanthraquinone Layers on Au(111)
Authors: Noh Seung‐Kyun , Jeon Jeong Heum , Jang Won Jun , Kim Howon , Lee Soon‐Hyeong , Lee Min Wook , Lee Jhinhwan , Han Seungwu , Kahng Se‐Jong
Published: March 2013

The role of halogen bonds in self‐assembled networks for systems with Br and I ligands has recently been studied with scanning tunneling microscopy (STM), which provides physical insight at the atomic scale. Here, we study the supramolecular interactions of 1,5‐dichloroanthraquinone molecules on Au(111), including Cl ligands, by using STM. Two different molecular structures of chevron and square networks are observed, and their molecular models are proposed. Both molecular structures are stabilized by intermolecular Cl⋅⋅⋅H and O⋅⋅⋅H hydrogen bonds with marginal contributions from Cl‐related halogen bonds, as revealed by density functional theory calculations. Our study shows that, in contrast to Br‐ and I‐related halogen bonds, Cl‐related halogen bonds weakly contribute to the molecular structure due to a modest positive potential (σ hole) of the Cl ligands.
Cenozoic climate change and diversification on the continental shelf and slope: evolution of gastropod diversity in the family Solariellidae (Trochoidea)
Authors: Williams S. T. , Smith L. M. , Herbert D. G. , Marshall B. A. , Warén A. , Kiel S. , Dyal P. , Linse K. , Vilvens C. , Kano Y.
Published: March 2013

Recent expeditions have revealed high levels of biodiversity in the tropical deep‐sea, yet little is known about the age or origin of this biodiversity, and large‐scale molecular studies are still few in number. In this study, we had access to the largest number of solariellid gastropods ever collected for molecular studies, including many rare and unusual taxa. We used a Bayesian chronogram of these deep‐sea gastropods (1) to test the hypothesis that deep‐water communities arose onshore, (2) to determine whether Antarctica acted as a source of diversity for deep‐water communities elsewhere and (3) to determine how factors like global climate change have affected evolution on the continental slope. We show that although fossil data suggest that solariellid gastropods likely arose in a shallow, tropical environment, interpretation of the molecular data is equivocal with respect to the origin of the group. On the other hand, the molecular data clearly show that Antarctic species sampled represent a recent invasion, rather than a relictual ancestral lineage. We also show that an abrupt period of global warming during the Palaeocene Eocene Thermal Maximum (PETM) leaves no molecular record of change in diversification rate in solariellids and that the group radiated before the PETM. Conversely, there is a substantial, although not significant increase in the rate of diversification of a major clade approximately 33.7 Mya, coinciding with a period of global cooling at the Eocene–Oligocene transition. Increased nutrients made available by contemporaneous changes to erosion, ocean circulation, tectonic events and upwelling may explain increased diversification, suggesting that food availability may have been a factor limiting exploitation of deep‐sea habitats. Tectonic events that shaped diversification in reef‐associated taxa and deep‐water squat lobsters in central Indo‐West Pacific were also probably important in the evolution of solariellids during the Oligo‐Miocene.
Tetraalkylphosphonium Decavanadates: Synthesis, Structures, and Solution Properties
Authors: Mal Sib Sankar , Tröppner Oliver , Ivanović‐Burmazović Ivana , Burger Peter
Published: March 2013

A novel intercluster compound, [(n‐C4H9)4P]3[H3V10O28] (IL01‐V10), constructed from the tetrabutylphosphonium cation and decavanadate, has been synthesized and unequivocally characterized by elemental analysis, FTIR spectroscopy, mass spectrometry, X‐ray crystallography, and solution 1H, 13C, 31P{1H}, and 51V NMR spectroscopy. Compound IL01‐V10 was formed by ionic interaction between the phosphonium cation and the decavanadate anion. Cryospray high‐resolution mass spectrometry revealed the [H3V10O28]3– cluster remains intact in solution. Three further phosphonium polyoxovanadates were synthesized and characterized by the same techniques as used for IL01‐V10.
Stereoselective Synthesis and Absolute Configuration Determination of Xylariolide A
Authors: Botubol José Manuel , Macías‐Sánchez Antonio J. , Collado Isidro G. , Hernández‐Galán Rosario
Published: March 2013

The asymmetric synthesis of the antibacterial and antitumoral natural compound xylariolide A (1) and five stereoisomers has been achieved. The strategy is based on the one‐pot epoxidation/lactonisation or dihydroxylation/lactonisation of the hypothetical biosynthetic intermediate xylarioic A acid (8). The absolute configuration of xylariolide A was thus determined to be 3R,4S,5R,1′R,2′R after the synthesis of 1, two epimers, i.e., 1′‐epi‐xylariolide A (3) and 2′‐epi‐xylariolide A (4), and three more diastereoisomers 5–7.
Convergent Strategy Towards the Synthesis of Restricted Analogues of Peloruside A
Authors: Zimmermann Nicolas , Pinard Pierre , Carboni Bertrand , Gosselin Pascal , Gaulon‐Nourry Catherine , Dujardin Gilles , Collet Sylvain , Lebreton Jacques , Mathé‐Allainmat Monique
Published: March 2013

A rapid convergent strategy to access unsaturated analogues of peloruside A has been demonstrated. This is depicted as an original C11–C12 aldol connection between a C12–C20 ketone fragment and a C2–C11 pyran fragment bearing an aldehyde function, with high yield and a good level of diastereoselectivity. The desired unsaturated macrocycle was obtained by a late‐stage ring closing metathesis reaction.
Removal of arsenic from drinking water by batch and continuous electrocoagulation processes using hybrid Al‐Fe plate electrodes
Authors: Kobya M. , Akyol A. , Demirbas E. , Oncel M.S.
Published: March 2013

Removals of arsenic from drinking water by electrocoagulation (EC) process using six different combinations of hybrid electrodes (Al‐Fe), and Al‐Al or Fe‐Fe electrodes as all anodes and cathodes in a batch mode were evaluated. The removal process with monopolar series mode at optimum operating conditions (2.50 A/m2, 150 µg/L, and pH 7.0) indicated that Fe‐Al‐Al‐Fe (anode‐cathode‐anode‐cathode) hybrid plate electrode pairs were the most efficient choice in terms of arsenic removal efficiency (96% in 1 min) and operating cost (0.00202 €/m3). The arsenic removal from drinking water by continuous EC (CEC) process using Fe‐Al‐Al‐Fe hybrid plate electrode pairs was also studied with respect to flow rates and initial arsenic concentrations. The effluent arsenic concentration of ≤10 µg/L in the CEC process was achieved at 3 min for 0.05 L/min (5.9 µg/L), 8 min for 0.10 L/min (6.3 µg/L), and 20 min for 0.20 L/min (8.4 µg/L), respectively. Amounts of the sludge and operating costs in the CEC process with respect to some experimental parameters such as operating time (3–20 min) and flow rate (0.05–0.20 L/min) at 150 µg/L were determined as 0.0095–0.025 kg/m3 and 0.009–0.060 €/m3. © 2013 American Institute of Chemical Engineers Environ Prog, 33: 131–140, 2014