bluuebunny/crossref_metadata_2025 huggingface dataset:
Antifungal Susceptibility Pattern of Candida Species Isolated from Sputum Samples in a Tertiary Care Hospital, Salem
Authors: Anukraha R. Janani , Sengodan Rajesh
Published: July 2023

Candida species are by far, the most common fungal pathogens in humans. Recovery of Candida species from the respiratory tract usually indicates commensalism/colonisation rather than infection. However this study aims at the distribution and antifungal susceptibility pattern of different Candida species isolated form colonised and infected patients with respiratory tract infections. Methods: This prospective study was conducted at a tertiary care hospital in Salem for 6 months. A total of 200 sputum samples were examined. Species identification and antifungal susceptibility testing was performed using disc diffusion method according to CLSI guidelines. Results: Out of 200 samples, 27 samples were found to have Candida spp of which Candida albicans 11 (41%) was the most common isolate followed by Candida tropicalis (25.90%), Candida parapsilosis (18.50%), Candida glabarata (11.11%) and Candida krusei (3.7%). Candida isolates showed more susceptibility to Amphotericin B (100%) & Voriconazole (100%) followed by Itraconazole (63%) and Fluconazole (62%). They also revealed higher resistance to Ketoconazole (46%). Conclusion: In hospitalised patients, Candida infection is a significant problem and resistance to commonly used antifungal agents are increasing. So the necessity of accurate and rapid identification of Candida species and its antifungal susceptibility pattern lead to better treatment because delay can result in increased mortality and morbidity in the patients.
Study of the HIV-1 RNA Levels and CD4+ Cells Counts in HIV Infected Patients
Authors: Chauhan Neelam , Shiv Kumar Anshusharma , Samar Neera , Mishra Madhubala
Published: July 2023

HIV infection is a global pandemic. There is an inverse relationship between CD4 counts and degree of immunosuppression. The present study aim to assess the use of viral load (HIV RNA) and CD4 cell counts in the monitoring of HIV progression and its correlation. This period of 20 months study was conducted on 300 seropositive patients attending ICTC in Department of Microbiology at the tertiary care hospital, fulfilling inclusion and exclusion criteria. CD4 counts were estimated at baseline (Pre ART) and after 6 months and 12 months. Viral load test had done at 6 and 12 months of Post ART. This study didn’t show any significant comparison between HIV RNA levels and CD4 cell counts after 6 months of ART treatment, but after 12 months there was significant negative linear correlation. 12 months of Post ART, TND number of patients increased from 152 patients to 215 patients. Patients who had VL>1000 copies/ml decreased from 27 patients to 10, only 1 patient showed static CD4 counts but achieved TND of viral load. We can conclude that combined use of CD4 and Viral load prognostic markers should prove useful in individual patient management and in the design and evaluation of therapeutic trials.
Heat Resistance Assay and Identification for Bacillus spp. spores Isolated from Raw Milk
Authors: Bui The Vinh , Thi Phuong Lien Luong , Thi Kim Loan Le , Ngo Thanh Phong , Huynh Le Dat
Published: July 2023

Heat-resistant spore-forming Bacillus spp. can survive the heat treatment process of milk and lead to spoilage of the final product. The objective of the research is to assay heat-resistant ability (D values, minutes) for Bacillus spp. spores. A total of 7 Bacillus spp. spores from eight of raw milk samples were tested biochemical properties and measured heat resistance in 1% peptone solutions. The best heat-resistant spores were chosen to identify them by 16S rRNA genes sequencing. The results showed that all of them belonged to the species of genus Bacillus, survived at the heat treatment of 90 °C for 12 minutes with the D values ranging from 1.86 to 23.66 minutes. Among of them, the best heat-resistant spores, namely BT2 and OM1, survived at the heat treatment of 100 °C for 30 minutes with the D values of 8.78 and 4.89 minutes, respectively; and were identified as Bacillus sporothermodurans BT2 and Bacillus cereus OM1, respectively.
Improvement of Fibrinolytic Enzyme Production from Bacillus sp. ES4 by Response Surface Methodology and Exponential Fed-Batch Fermentation
Authors: Thanh Bui Thi , Tuan Le , Lan Huong Nguyen , Tuan Anh Pham
Published: July 2023

To improve the fibrinolytic enzyme production of the mutant strain Bacillus sp. ES4, the response surface methodology was used to optimize the medium composition. Thirty-four flask scale experiments were carried out, and the results were fitted to quadratic models using Design-Expert software. The ANOVA analysis revealed that medium components differently affect cell density and fibrinolytic enzyme production. At optimal condition for fibrinolytic enzyme production, enzymatic activity attained 686 ± 43 FU/mL, which is increased by 1.7-fold compared to the initial medium (404 ± 4 FU/mL). One step fed-batch fermentation, in which the nutrient for optimal enzymatic activity was exponentially feed to the culture, improved fibrinolytic enzyme activity by 5.91-fold (4,057.14±57.14 FU/mL) and cell density by11.9-fold (101.2±0.005). In two steps fed-batch fermentation, the nutrient for optimal cell density was first used, then followed by feeding for optimal enzyme activity. The highest cell density (OD600nm) and fibrinolytic enzyme activity reached 142.3 ± 0.0125 and 5,300 ± 100 FU/mL, respectively after 13 h fermentation. Ultimately, the medium optimization and fed-batch strategy collectively improved fibrinolytic enzyme activity by 13.12-fold.
Impact of Different Pre Sowing Treatments with Organics and Botanicals on Growth Yield and Yield Attributing Traits of Sweet Corn
Authors: Swathi Priya Uppe , Kumar Rai Prashant , Sankar Narayana Kariyappa
Published: July 2023

Seeds treated with chemicals are usually toxic to humans and animals. So as an alternative approach, a field experiment was carried out during Kharif season of 2021 to study the impact of different pre sowing treatments with organics and botanicals on growth, yield and yield attributing traits of Sweet corn (Zea mays L.). Experiment was subjected to13 pre sowing treatments each replicated thrice. Seed treatment with T3 Panchagavya at 7% for 12 hours was most effective in improving growth and yield parameters viz., Field emergence percentage (92.22%), Plant height (209.13cm), days to maturity (76.33), Cob length (18.36cm), Seed index (25.8g), Seed yield per plant(330.05g), Seed yield per plot (5.51t/ha), Biological yield (15.27t/ha) and Harvest index(35.83%). This study revealed that pre sowing treatments with organics and botanicals can be significantly effective in enhancing the growth and yield parameters of Sweet corn and they are of low cost, eco-friendly and toxic free.
Trancsriptome Sequencing: Emerging Tool to Reveal Genomic Data and Gene Function
Authors: Gupta Akhil , Singh S. K.
Published: July 2023

All the information present in a cell, an organism possesses to survive is known as genetic information. It stores, processes and transmits biological data from generation to generation. The first step in decoding these genetic instructions is to copy part of the base sequence from DNA into RNA.RNA sequencing provide insight into the transcriptome of a cell. RNA-sequencing has multiple applications in agriculture, animal husbandry, and health. For research that involves monitoring the cellular response to stimuli, treatment or environment change, understanding the differential gene expression patterns can provide insights into their physiological responses. Profiling the various RNA molecules provides insights into factors defining specific phenotypes for e.g. the color of fruit, medicinal properties of herbs, seed phenotype, secondary metabolites in plants, etc. Further, Transcriptome analysis is widely used to gain insight into processes such as cellular differentiation, transcription regulation, polymorphism, biomarker discovery & prediction of some useful genes and their functional validation.
Selection Indices Studies in Ajwain (Trachyspermum ammi L. Sprague)
Authors: Bramhane Ashish Ravindra , Deshmukh D. T. , Ghawade S. M. , Phad D. S. , Patil D. S.
Published: July 2023

The present investigation entitled “Correlation and Path Analysis and Studies in Ajwain (Trachyspermum ammi L. Sprague)” was carried out with fifteen genotypes including three checks. The experiment was conducted in Randomized Block Design with three replication during rabi 2020-2021 at Chilli & Vegetable Research Unit, Dr. PDKV, Akola. The observations were recorded on five randomly selected plants for nine characters viz., days to first flowering, days to 50 per cent flowering, days to maturity, plant height at maturity, number of primary branches per plant, number of umbels per plant, number of umbellates per umbel, test weight and seed yield per plant. The data so obtained was subjected to analysis of variance and selection indices study. In the present study, the mean performance of genotypes revealed a wide range of variability for all the characters. Significant highest mean values were recorded for seed yield per plant in genotype AKAJ-18-13-21 (7.62 g) followed by AKAJ-18-10-21 (7.16 g) and AA-2 (7.12 g). Genotypes viz., AKAJ-18-13-21 and AKAJ-18-05-21 were found to be early maturing among experimental material. The selection indices studies indicated that the individual trait index, number of umbels per plant had the highest relative efficiency (101.507 per cent) indicated the importance of this trait as yield attribute. In this present investigation, selection index based on three characters (number of umbels per plant + number of umbellates per umbel + test weight) showing genetic gain (2.444) and relative efficiency (104.504 per cent) is more desirable and practically possible to use than those based on four or more characters.
Resource Use Efficiency on Cotton Production under Contract and Non-Contract Farming in Kallakkurichi District of Tamil Nadu, India
Authors: Rengaraju R. , Kokila G. , Azhagesan R.
Published: July 2023

Cotton is the king of fiber, usually called White gold and is considered to be an industrial commodity of worldwide importance. Contract farming can be understood as a firm lending “inputs” such as seed, fertilizer, credit or extension to a farmer in exchange for exclusive purchasing rights over the specified crop. The objectives of the study is (1) to analyse the resource use efficiency of cotton production on contract and non-contract farming situation and (2) to study the problems faced by the contract farmers and non-contract farmers in the study area. Kallakurichi district was purposively selected for the present study since it occupied the large position in area and production of Cotton and this district has black soil which is suitable for cotton production. The R2 value of 0.77 indicates that about 77% of the variation in cotton yield by contract farming was influenced by the explanatory variables and the R2 value of 0.94 indicates that about 94% of the variation in cotton yield by contract farming is influenced by the explanatory variables included in the model. High rate of input cost was ranked first with of 95%, followed by lack of credit facility for production, frequent power cuts, farmers facing difficulty in meeting the quality requirements (70%). The constraints in non-contract farming method of Cotton cultivation were Low quality input of seeds, pesticides, fertilizers etc., and Price volatility and an uncertain market (91.66%) together ranking first followed by other constraints.
Determinants of BSI mobile banking adoption intentions: DeLone & McLean and UTAUT Model integration with religiosity
Authors: Sholihah Erlinda , Antari Ika Septiana Windi , Rochimawati Rizqi Fajar , Ulwiyyah
Published: July 2023

Purpose − This research aims to identify influencing factors on BSI mobile banking adoption intention by integrating the UTAUT and DeLone & McLean models and the role of religiosity variables.Methodology − This research used primary data from 150 Bank Syariah Indonesia customers who used mobile banking. The analysis method applied SEM PLS to assess the relation among exogenous and endogenous variables using SmartPLS software.Findings − The findings show that from the factors identified, Service Quality, Information Quality, Performance Expectancy, Effort Expectancy, Social Influence, and Religiosity are critical variables in BSI mobile banking adoption intention. Because these six factors significantly impact the intention of BSI Mobile Banking adoption.Implications − Our work helps stakeholders strategize and policy to offer more innovative and flexible production technologies. So, the bank must pay more attention to things that support the increasing performance of mobile banking to increase customer intentions in adopting BSI mobile banking.Originality − This research provides a theoretical contribution in integrating the UTAUT and DeLone & McLean models, including the role of religiosity variables in assessing the adoption intention factors of BSI mobile banking in Indonesian society.
Interactive marketing and relationship quality in Islamic banking: A Parepare case study
Authors: Addury Multazam Mansyur , Pangestu Dian Resky
Published: July 2023

Purpose − This research aims to analyze the effects of interactive marketing and relationship quality on customer satisfaction and loyalty in Islamic banking.Methodology − A quantitative research approach was employed, and data was collected through a survey questionnaire administered to customers of Islamic banks in Parepare. The data analysis method used in this study is Partial Least Squares-Structural Equation Modeling (PLS-SEM).Findings − The study findings indicate that, indirectly, interactive marketing and relationship quality do not have a direct significant influence on customer loyalty in Islamic banks. However, it is observed that interactive marketing and relationship quality can affect customer loyalty through satisfaction. These findings suggest that the process of maintaining and enhancing customer loyalty in Islamic banks requires careful attention to multiple factors and stages.Implications − This research emphasizes the significance of integrating interactive marketing strategies, fostering relationship quality, and prioritizing customer satisfaction in the context of Islamic banks. These factors are essential for maintaining and strengthening customer loyalty, ultimately contributing to the long-term success and competitiveness of Islamic banks in Kota Parepare.Originality − The originality of this research lies in its contextual focus and integration of variables. Firstly, the study specifically examines the impact of interactive marketing and relationship quality on customer satisfaction and loyalty within the context of Islamic banks in Kota Parepare. Secondly, the study integrates multiple variables, including interactive marketing, relationship quality, customer satisfaction, and customer loyalty, providing a comprehensive understanding of the factors that contribute to customer loyalty in the context of Islamic banks.
The Holy and everyday life among Brazilian Lutherans: Syncretisms
Authors: Bobsin Oneide
Published: July 2023

The article is a theoretical effort to understand the religious practices of “laypersons” in the submersed part of church institutions. Such religious practices, called “popular religiosity” by sociology of religion in Brazil, are exemplified by three different characters, one of whom is taken from a work of fiction of Brazilian literature. They do not break with the official political or ecclesiastical order but reinterpret institutional discourses in the pragmatic dynamics of the search for a religion of survival. The socio-existential dilemmas of their everyday lives mark their utterances in the search for meaning, particularly in the area of health and the precariousness of the world of labor. They navigate through the official utterances of institutions and express the worldview and the needs of the poor population strata, but not only of the latter. Persons of the affluent classes also turn to the religiosity of the underground of social life. They act on the margins of institutions and in many cases create their own churches or religious organizations or are committed to them in various ways. Finally, the article also points to a theological effort—still in embryo—to understand religious practices that coexist with official discourses.
Religião, discurso religioso e saúde mental
Authors: Santos Francisco de Assis Souza , Lidiane da Silva
Published: July 2023

O presente artigo se propõe a estabelecer uma interface dialógica entre a religião, o discurso religioso e a saúde mental. A religião, seja ela qual for, quando não equilibradas, pode causar danos à saúde mental e comportamental de pessoas fragilizadas em sua identidade e que se ligam a algum grupo religioso. Objetivou-se refletir e discutir como e porque a religião levada ao extremo contribui para certas condutas de efeitos negativos, inclusive a certo grau de fanatismo que resulta na necessidade de intervenção psiquiátrica ou ainda possa, no caso de predisposição genética, desenvolver doenças psicopatológicas ou surtos psicóticos a ponto de o sujeito atentar contra a própria vida. Inferiu-se daí que pacientes psiquiátricos são facilmente manipulados pelo discurso de religiões avivadas, com grandes chances de se tornarem fanáticos religiosos e abandonarem o tratamento medicamentoso, acreditando na cura pela fé – consequência que os leva à piora da saúde mental. Entende-se que o objetivo das diferentes religiões é promover equilíbrio, conforto  e bem-estar na relação do ser humano com o sagrado, tentando assim atender aos anseios profundos que conduzam ao entendimento de sua existência.
ReliaMatch: Semi-supervised Classification with Reliable Match
Authors: Jiang Tao , Chen Luyao , Chen Wanqing , Meng Wenjuan , Qi Peihan
Published: July 2023

Deep learning has been widely used in various tasks such as computer vision, natural language processing, and predictive analysis, recommendation systems in the past decade. However, practical scenarios often lack labeled data, posing challenges for traditional supervised methods. Semi-supervised classification methods address this by leveraging both labeled and unlabeled data to enhance model performance, but they face challenges in effectively utilizing unlabeled data and distinguishing reliable information from unreliable sources. This paper introduces ReliaMatch, a semi-supervised classification method that addresses these challenges by using a confidence threshold. It incorporates a curriculum learning stage, feature filtering, and pseudo-label filtering to improve classification accuracy and reliability. The feature filtering module eliminates ambiguous semantic features by comparing labeled and unlabeled data in the feature space. The pseudo-label filtering module removes unreliable pseudo-labels with low confidence, enhancing algorithm reliability. ReliaMatch employs a curriculum learning training mode, gradually increasing training dataset difficulty by combining selected samples and pseudo-labels with labeled data. This supervised approach enhances classification performance.

Experimental results show that ReliaMatch effectively overcomes challenges associated with the underutilization of unlabeled data and the introduction of error information, outperforming the pseudo-label strategy in semi-supervised classification.
Insight into the Potential Mechanisms of Endocrine Disruption by Dietary Phytoestrogens in the Context of the Etiopathogenesis of Endometriosis
Authors: Szukiewicz Dariusz
Published: July 2023

Phytoestrogens (PEs) are estrogen-like nonsteroidal compounds derived from plants (e.g., nuts, seeds, fruits and vegetables) and fungi that are structurally similar to 17β-estradiol. PEs bind to all types of estrogen receptors, including ERα and ERβ receptors, the nuclear receptors, and a membrane-bound estrogen receptor known as the G protein-coupled estrogen receptor (GPER). As endocrine-disrupting chemicals (EDCs) with pro‐ or antiestrogenic properties, PEs can potentially disrupt hormonal regulation of homeostasis, resulting in developmental and reproductive abnormalities. However, the lack of PEs in the diet does not result in the development of deficiency symptoms. To properly assess the benefits and risks associated with the use of a PE-rich diet, it is necessary to distinguish between endocrine disruption (endocrine-mediated adverse effects) and nonspecific effects on the endocrine system. Endometriosis is an estrogen-dependent disease of unknown etiopathogenesis, in which tissue similar to the lining of the uterus (the endometrium) grows outside of the uterus with subsequent complications being manifested as a result of local inflammatory reactions. Endometriosis affects 10–15% of women of reproductive age and is associated with chronic pelvic pain, dysmenorrhoea, dyspareunia and infertility. In this review, the endocrine-disruptive actions of PEs are reviewed in the context of endometriosis to determine whether a PE-rich diet has a positive or negative effect on the risk and course of endometriosis.
Efforts to improve sprint learning outcomes in physical education learning through a play approach to fourth grade elementary school students
Authors: Sukma Hidayat Adi
Published: July 2023

This research is motivated by the lack of active student participation in the learning process of physical education, sports and health, so that student learning outcomes are still relatively low. This study aims to improve the learning outcomes of sprinting by applying a play approach in physical education learning in fourth grade students of SD AL QURAN Metro Barat for the 2019/2020 academic year. This type of research is Classroom Action Research. This research was carried out in two cycles, each cycle having 3 meetings. The research subjects were fourth grade students of SD AL QURAN Metro Barat for the 2019/2020 academic year which consisted of 20 students, on the subject of sprinting. Based on the results of data analysis and discussion, it is concluded that the play approach in physical education learning can improve sprint learning outcomes for fourth grade students of SD AL QURAN Metro Barat for the 2019/2020 academic year. This can be seen from the increase in the ability to run fast in the initial conditions (9.675 seconds), cycle I (9.435 seconds) and cycle II (9.24 seconds), so that the increase from the initial condition to cycle II is (0.435 seconds). While the value of mastery learning outcomes in the initial conditions (30%), cycle I (55%) and cycle II (90%), so that the increase from the initial condition to cycle II was (60%).
The Effectiveness of the Android Application on the Lesson Bottom Pass Learning Outcomes of Volleyball for Class X Students
Authors: Cahyani Septiana Dwi , Novianti Winda Pramalia
Published: July 2023

Until now, after the pandemic began to subside and face-to-face learning mode is held, smartphones have become a supporting object in almost every aspect of students' daily activities, because they are considered practical and efficient. Researchers want to develop android-based interactive learning media on volleyball material that can help PJOK teachers in delivering learning materials that are interesting and easy to understand for students, so that students are not bored and learning objectives can be achieved. The android application is designed to display a variety of materials, learning videos, to cognitive assessments. The study was conducted to test the effectiveness of the Android Application towards the Learning Outcomes of Passing Down Volleyball Students in Grade X of SMAN 1 Bandongan. Based on experimental research using quantitative data analysis, it was concluded that the android application was effective and efficient on student learning outcomes, especially the basic technique of passing down volleyball.
Application of the problem-based learning learning model to improve basketball dribbling learning outcomes in class VIII-I students of SMP Negeri 1 Karanganyar
Authors: Aji Taufan Susilo
Published: July 2023

Tujuan Penelitian ini adalah untuk meningkatkan hasil belajar dribbling bola basket melalui penerapan model pembelajaran Problem Based Learning pada peserta didik kelas VIII-I SMP Negeri 1 Karanganyar Tahun Pelajaran 2021/2022.

Penelitian ini merupakan penelitian tindakan kelas (PTK). Penelitian ini dilaksanakan dalam dua siklus, dengan tiap siklusnya terdiri atas dua kali pertemuan. Subjek penelitian adalah peserta didik kelas VIII-I SMP Negeri 1 Karanganyar yang berjumlah 30 peserta didik yang terdiri dari 14 peserta didik putra dan 16 peserta didik putri. Sumber data berasal dari guru, peserta didik, dan peneliti. Teknik pengumpulan data adalah dengan observasi, wawancara, tes, dan dokumentasi atau arsip. Validitas data menggunakan teknik triangulasi yang terdiri dari triangulasi metode, trangulasi sumber, dan triangulasi data. Analisis data menggunakan teknik analisis deskriptif kualitatif dengan teknik persentase untuk melihat kecenderungan yang terjadi dalam kegiatan pembelajaran pendidikan jasmani.

Hasil analisis data yang terjadi pada pratindakan ke siklus I, dan siklus I ke siklus II dapat disampaikan sebagai berikut: Pada pratindakan hasil belajar dribbling bola basket pada aspek kognitif yang tuntas adalah 11 peserta didik dengan persentase 36%, sedangkan pada aspek psikomotor jumlah peserta didik yang tuntas adalah 15 peserta didik dengan persentase 50% dan pada aspek afektif jumlah peserta didik yang tuntas adalah 30 peserta didik dengan persentase 100%, kemudian pada siklus I hasil belajar dribbling bola basket pada apek kognitif jumlah peserta didik yang tuntas adalah 18 peserta didik dengan persentase 60%, sedangkan pada aspek psikomotor jumlah peserta didik didik yang tuntas adalah 23 peserta didik dengan persentase 76%, selanjutnya pada siklus II hasil belajar dribbling bola basket pada aspek kognitif jumlah peserta didik yang tuntas adalah 24 peserta didik dengan persentase 80%, sedangkan pada aspek psikomotor jumlah peserta didik yang tuntas adalah 27 peserta didik dengan persentase 90%. Hasil belajar dribbling bola basket sudah mencapai target yang ditentukan sehingga tindakan dapat dihentikan pada siklus II. Dari hasil analisis data di atas dapat disimpulkan bahwa pembelajaran melalui model pembelajaran Problem Based Learning dapat meningkatkan hasil belajar dribbling bola basket pada peserta didik kelas VIII-I SMP Negeri 1 Karanganyar Tahun Pelajaran 2021/2022.

Kata Kunci: Hasil Belajar, Dribbling Bola Basket, Penerapan Model Pembelajaran Problem Based Learning.
Effect of Sports Massage Manipulation on Pain Intensity After Eccentric Exercise
Authors: Nurmaya Ika , Roepajadi Joesoef , Susanto Indra Himawan , Nugraha Testa Adi , Fikri Muhammad Dzul
Published: July 2023

The purpose of this study was to analyze the effect of sports massage manipulation which is often used as passive recovery by measuring pain intensity using a visual analog scale (VAS) after eccentric exercise. This type of research is quantitative, with a quantitative descriptive design using a questionnaire (VAS), and data analysis method from examining pain intensity before and after manipulation of massage therapy. 54 athletes at the Indonesian National Sports Committee (KONI) in the Sidoarjo district participated as subjects. Using the Descriptive Statistical test before and after the massage therapy manipulation was carried out using the table or graphic diagram method, and the data obtained would be processed using SPSS for Windows v.22. It shows the mean (average) results of respondents' answers from respondents' answers about perceived pain intensity. From the results of testing the normal distribution of data using the Kolmogorov-Smirnov normality test, and then using the Wilcoxon test and the result was that there was a difference between pre and post-giving sport massage after eccentric exercise on pain intensity. From this study, it was concluded that giving sports massages had an effect on reducing pain intensity after eccentric exercise
Pemanfaatan Live Worksheet sebagai E-LKPD Pendidikan Pancasila materi Kolaborasi Antar Budaya di Indonesia
Authors: Ma'arif Mahmuda , Nissa Desti Fitria , Aulia Syifa Siti , Immaniar Desi Nurul
Published: July 2023

Penelitian ini bertujuan menggali kreativitas guru dalam proses pembelajaran Pendidikan Pancasila Materi Kolaborasi Antar Budaya di Indonesia melalui pemanfaatan Live Worksheet. Ruang lingkup penelitian meliputi perencanaan, pelaksanaan, dan evaluasi pemanfaatan live worksheet yang dikembangkan Guru Pendidikan Pancasila dan Kewarganegaraan Sekolah Menengah Atas Negeri 1 Suboh Situbondo. Metode penelitian  menggunakan pendekatan kualitatif dengan menggali secara alamiah proses pemanfaatan live worksheet dalam pembelajaran. Keabsahan data menggunakan triangulasi untuk membandingkan antara hasil wawancara, dokumentasi, dan observasi. Hasil penelitian menunjukkan bahwa Live worksheet berfungsi sebagai alat bantu penugasan peserta didik. Live worksheet sebagai bentuk E-LKPD menjadi alat evaluasi yang tepat untuk melihat bagaimana peningkatan pemahaman peserta didik terhadap materi kolaborasi antar budaya di Indonesia. Dibuktikan dengan data melihat adanya perbedaan hasil nilai belajar peserta didik kelas X E pada pre test dengan jumlah 10 peserta didik yang tuntas, dengan presentasi 31% dan pada penilaian post test E-LKPD berbasis live worksheet dengan 22 peserta didik yang tuntas dengan presentase 68%. Kesimpulannya E-LKPD dengan live worksheet materi kolaborasi antar budaya di Indonesia dengan hasil belajar yang baik dan meningkat serta mudah digunakan.
Kegiatan Adiwiyata Sebagai Sarana Penanaman Profil Pelajar Pancasila di Sekolah Dasar
Authors: Azizah Nilam Pritami Nur , Amalia Nur
Published: July 2023

Pembelajaran berbasis proyek identik dengan kurikulum merdeka belajar. Maka dari itu, sekolah diharuskan memiliki program untuk pelaksanaan Projek Penguatan Profil Pelajar Pancasila. Penelitian ini bertujuan untuk mengetahui pelaksanaan kegiatan adiwiyata dan mendiskripsikan kegiatan adiwiyata sebagai sarana penanaman profil pelajar Pancasila. Metode penelitian yang digunakan yaitu kualitatif deskriptif. Pengumpulan data diperoleh melalui observasi, wawancara, dan dokumentasi. Hasil penelitian menunjukkan dalam pelaksanaan kegiatan adiwiyata Sekolah Dasar Negeri 12 Sragen menggunakan 3 prinsip yaitu edukasi, partisipasi dan berkelanjutan. Peran kegiatan adiwiyata dalam penanaman karakter profil pelajar Pancasila yaitu bahwa penerapan profil pelajar Pancasila  dalam penguatan karakter dapat dilaksanakan melalui kegiatan adiwiyata yaitu Beriman bertaqwa kepada Tuhan Yang Maha Esa dan berakhlak mulia berdoa sebelum kegiatan. Berkebinekaan global yaitu dengan siswa mampu berinteraksi untuk menumbuhkan sikap  peduli terhadap lingkungan. Bergotong royong dengan melakukan kolaborasi antara warga sekolah dalam pembuatan pupuk kompos, dan melaksanakan piket yang terjadwal. Kreatif dengan inovasi kreasi seperti pot bunga, bunga plastik  dari bahan bekas. Bernalar kritis yaitu dengan membuang sampah sesuai dengan jenis kelompoknya dan kemandirian melalui kegiatan menanam dan merawat tumbuhan masing–masing.
Bantuan Hukum Pro Bono Publico dalam Pemenuhan Hak Memperoleh Keadilan dan Persamaan di Muka Hukum di Provinsi Jawa Timur
Authors: Abu Bakar Bakri Dina  Susiani
Published: July 2023

Law enforcement in Indonesia is complex and not easy. Since the Legal Aid Law was passed in 2011, various hopes have begun to emerge for the development of a legal aid system that can be accessed by all groups of society, especially the poor (poor). However, along the way, there are still many weaknesses and need significant improvement. Therefore the problem is how to implement the provision of free legal aid (pro bono publico) by the local government for the poor in East Java province; as well as how the coordination between the Regional Government of East Java Province and the Regional Office of the Ministry of Law and Human Rights of East Java as providers of legal aid in the regions. This research method uses a qualitative approach that is descriptive. Then carried out a qualitative analysis of the substance and context of the research from the aspect of human rights. The practice of providing legal aid to the poor in East Java Province is still experiencing obstacles, including the lack of socialization regarding the provision of legal aid to the poor, the minimal number of Legal Aid Organizations (OBH) in providing legal aid, the amount of legal aid costs is insufficient in the process at the trial, as well as administrative requirements related to the Certificate of Disability (SKTM) which was misused by several individuals and did not match its purpose.
Prevalencia de obesidad y factores de riesgo asociados en adultos mexicanos: resultados de la Ensanut 2022
Authors: Campos-Nonato Ismael , Galván-Valencia Óscar , Hernández-Barrera Lucía , Oviedo-Solís Cecilia , Barquera Simón
Published: July 2023

Objetivo. Describir la prevalencia de obesidad en adultos, medida a través del índice de masa corporal (IMC) y la circunferencia de cintura (CC), estratificando por factores de riesgo y comorbilidades. Material y métodos. Se analizó la información de 8 563 participantes en la Encuesta Nacional de Salud y Nutrición 2022 (Ensanut 2022). Se clasificó la obesidad por IMC y por CC. Se calcularon razones de momios (RM) para asociar la obesidad con factores de riesgo y diagnóstico de comorbilidades. Resultados. La prevalencia de sobrepeso fue 38.3%, obesidad 36.9% y obesidad abdominal (OA) 81.0%. Las mujeres tuvieron una mayor RM (1.4) de tener obesidad y OA (2.5). Los adultos con obesidad tenían una mayor posibilidad de tener diagnóstico de diabetes (RM 1.7), hipertensión (3.6) y dislipidemia (RM 2.3) que los adultos con IMC normal. Conclusiones. La prevalencia de obesidad en adultos mexicanos es una de las más altas a nivel mundial y está asociada con los factores de riesgo y enfermedades crónicas más frecuentes. Se requieren políticas públicas multisectoriales para prevenir y controlar la obesidad.
Dificultades de funcionamiento en la infancia, adolescencia y edad adulta en México, 2022
Authors: Vázquez-Salas R. Argelia , Hubert Celia , Pérez-Reyes María del Rocío , Allen-Leigh Betania
Published: July 2023

Objetivo. Conocer las prevalencias nacionales de dificultad del funcionamiento de niñas, niños, adolescentes y adultos. Material y métodos. La Encuesta Nacional de Salud y Nutrición 2022 utilizó los módulos de discapacidad del Fondo de las Naciones Unidas para la Infancia (Unicef) y el Grupo Washington. Se calcularon las prevalencias de dificultad del funcionamiento e intervalos de confianza al 95%. Resultados. El 14.4% de la población de 2-17 años presentó al menos una dificultad del funcionamiento, 3.9% entre 2-4 años y 16.7% para 5-17 años. El 9.7% de los adultos presentaron dificultad del funcionamiento, siendo más frecuente en mujeres (11.3%) y en índice de bienestar bajo (12.2%). Conclusión. Una de cada diez personas adultas en México experimentan dificultades de funcionamiento y es mayor en mujeres adultas y personas con índice de bienestar bajo. El Estado Mexicano debe detectar los problemas de funcionamiento potencialmente tratables y establecer programas de adecuación de los entornos para facilitar el funcionamiento de las personas.
Dissimilarity in root traits and spatial distribution promotes the productivity of Piper nigrum L. and tree species in mixture systems
Authors: Zu Chao , Li Zhigang , Yang Jianfeng , Wang Can , Wang Xin-Xin , Ji Hui , Shen Jianbo , Rengel Zed , Li Hongbo
Published: July 2023

Background and Aims
Clarifying why species mixtures produce greater biomass compared to monocultures is important to understand the effect of biodiversity in natural and agricultural systems. At present, it remains unclear whether differential root traits and spatial distribution between the liana and tree species can promote productivity of mixtures.
Methods
A 4-month glasshouse experiment and a 3-year field trial were conducted to examine the influence of root traits and vertical and horizontal root distribution on productivity of independently supported liana Piper nigrum(Pn) and five other species. In glasshouse experiment, Pn was grown in monoculture or mixed with one of five species: Coffea arabica, Areca catechu (Ac), Artocarpusheterophyllus, Camellia oleifera, and Coffea canephora. In the field trial, the Pn/Ac system and each monoculture were tested.
Results
Compared with monoculture, all Pn and mixture systems showed a positive net effect and high complementarity effect on shoot biomass. The variation in complementarity effect was mainly associated with dissimilarity in the multidimensional root space trait and a few specific individual traits (root phosphatase activity and mycorrhizal colonization) between Pn and neighbors. In the field, Pn in the mixture increased proportion of root length in the 20-40 cm soil layer, and allocated less root length in the space shared between Pn and Ac, thus achieving spatial separation of roots and promoting the final yield.
Conclusion
These findings suggest that the dissimilarity in root traits and spatial distribution may be an important mechanism for promoting the productivity of mixtures of liana and tree species.
Common Procedures in Emergency Medical Service Activities: A Nationwide Cross-sectional Study
Authors: Thepmanee Duangpon , Chalongviriyalert Piti
Published: July 2023

Background
Emergency medical services (EMS) are services offered to patients with life-threatening conditions such as cardiac arrest, respiratory failure, and major trauma. EMS have led to an increase in the number of procedures being performed in the field.
Methods
In this cross-sectional analytical study, we included all patients in the National Institute of Emergency Medicine (NIEM) dataset seen between 2017 and 2021. We explored the procedures of the EMS response case, the patient’s symptoms rate, and the patient outcome rate by the number and percentage of procedures.
Results
A total of 1,788,669 EMS responses were eligible for analysis of EMS procedures. The most frequent symptoms of the procedure were “unconsciousness or stupor” (21.63%), “dyspnea” (15.06%), and “seizure” (9.14%). Head injury was the most frequent injury type (49.69%). The most common EMS responses included intravenous fluid (IVF) (40%), such as 0.9% NSS (38.94%); airway and breathing (16%), such as O2 canular or mask bag (49%); immobilization (16%), such as collar with long spinal board (46%); stop bleeding (14%), such as pressure dressing (28.23%); medication administration (8%), such as 50% glucose (42.45%), adrenaline (27.9%), and diazepam (12.1%); and cardiopulmonary resuscitation (CPR) (5%), such as chest compression (38.94%) and automated external defibrillator (AED) or defibrillators (5.98%). As a result, patient outcomes of EMS procedures response found advantages 54% of symptoms improved and 21% of admission over 30 days.
Conclusions
The most common EMS procedures among emergency patients in Thailand are IVF, airway, breathing, immobilization, and stop bleeding. These data highlight good improving patient symptoms, in all prehospital and in-hospital phases. In the future, training for EMS providers regarding the need for EMS intervention should be increased.
Comprehensive evaluation of immune dysregulation and altered cytotoxic markers in secondary hemophagocytic lymphohistiocytosis (sHLH)
Authors: Wang Yun , Yuan Xu , Wang Ting , Wei Wei , Wu Shiji , hou hongyan
Published: July 2023

Background
Host immune dysfunction plays a crucial role in the onset, progression, and outcome of hemophagocytic lymphohistiocytosis (HLH). This study aimed to comprehensively evaluate the peripheral immune profiles in patients with newly diagnosed secondary hemophagocytic lymphohistiocytosis (sHLH), and explore their predictive value for patient prognosis.
Methods
A total of 77 patients with sHLH were enrolled in this study, with 31 of them experiencing mortality. Flow cytometry was used to assess the percentages, absolute numbers, and phenotypes of lymphocyte subsets. Simultaneously, cytokine levels and routine laboratory indicators were also collected.
Results
In patients with sHLH, the percentages of CD3 + T cells, CD4 + T cells, and NK cells were found to be decreased, while the percentages of CD8 + T cells and B cells were increased compared to healthy controls. Similarly, when compared to disease controls (DCs), the percentages of CD3 + T cells and CD4 + T cells were decreased, while the percentages of NK cells were increased. Furthermore, the absolute numbers of lymphocyte subsets were significantly impaired in sHLH patients. Specifically, a notable decreased in EMRA CD8 + T cells were observed. Additionally, there was a significant increase in the proportion of plasma cells within the B cell population. We further investigated the prognostic value of immune indicators in sHLH. Kaplan-Meier survival analysis revealed that lower levels of CD3 + T cells, higher levels of APTT and IL-6 were associated with a poor prognosis in sHLH patients.
Conclusions
The lymphocyte subsets in the sHLH group exhibited dysregulation, with significant impairments observed in the absolute numbers of various lymphocyte subsets. Notably, CD3 + T cells and IL-6 were identified as critical markers for predicting prognosis and identifying potential treatment targets in HLH.
Nanofluid Assisted-Chemical Oil Recovery Process at High Temperature and High Salinity Conditions: Nanofluid Stability, Interfacial Tension, Contact Angle, Microscale Experimental Investigation
Authors: Hashemi Mohammad , Tamsilian Yousef , Kord Shahin
Published: July 2023

One of the most important aspects to use the nanofluid flow through the oil recovery process is physical and chemical constraints at high salinity and temperature, harsh conditions, leading to the instability and further problems. In this study, the stability of various nanoparticles, Al2O3, SiO2, ZrO2, TiO2, Fe2O3, nanoclay, and ZnO, were examined upon the concentration (0.01 to 3 wt%), temperature (ambient and 75℃), salinity (20,000 to 80,000 ppm), pH (2 to 12), and stabilizers of polyethylene glycol, polyvinylpyrrolidone, guar gum, Triton X-100, sodium dodecyl sulfate, cetrimonium bromide. Then, the most stable nanofluid was nominated to investigate the oil recovery mechanisms by performing interfacial tension (IFT), wettability alteration, and micromodel flooding analyses. Zinc oxide and silicon dioxide nanofluids were maintained their stability at the harsh conditions and guar gum showed a good performance in stabilizing nanofluids, compared to other nanofluids agglomerated. According to the results of the IFT reduction upon the nanofluid and reservoir crude oil (1.64 mN/m), wettability alteration of carbonate cores (113.68 degree) and micromodel experiments (additional recovery of 32.23% and 6.27% in the secondary and tertiary flooding, respectively) all compared to the seawater, the ZnO nanofluid stabilized by guar gum was an excellent candidate to use in the oil recovery projects.
Soil bio-solarization and Trichoderma asperellum suppress black root rot disease and increase strawberry yield
Authors: Abd-El-Kareem Farid , Saied Nehal M. , Elshahawy Ibrahim E. , Abd-Elgawad Mahfouz
Published: July 2023

Trichoderma asperellum applied as pellets, disks, or spore suspension against the causal agents of strawberry-black root rot disease represented by three fungal species was tested. The pellets/disks could significantly reduce the growth area of the pathogenic fungi Rhizoctonia solani, Fusarium solani, and Macrophomina phaseolina in vitro. Solarization via mulching soil with transparent polyethylene sheets could affect these pathogens. It reduced the counts of the fungi buried in cloth bags at 1–10 cm of soil surface by 70, 65, and 65% for R. solani, F. solani, and M. phaseolina, respectively relative to unmulched soil. Yet, the more depths of bags in soil, the less the mulching affects the three pathogens. In two field experiments, the disease incidence and severity were more reduced when T. asperellum pellets/suspension was integrated with bio-solarization (mulching soon after bio-fumigation with Al-Abour Compost®)) than any single treatment. The highest reductions obtained by T. asperellum pellets combined with bio-solarization averaged 75 and 73.8%, respectively. Bio-solarization with Actamyl affected the disease incidence/severity to a lesser extent. All tested treatments significantly boosted yield of strawberry plants. Strawberry yield and activities of the pathogenesis-related proteins peroxidase and chitinase showed favorable responses almost parallel to the extent of reduction in the disease incidence and severity caused by all treatments. The highest yield increase achieved via combining T. asperellum pellets with bio-solarization was 160.8%. Our results support hypothetical biocontrol potential that T. asperellum and bio-solarization together with adequate phytosanitary measures can reliably control strawberry-black root rot disease and enhance strawberry yield.
Prediction of lymph node metastasis in patients with papillary thyroid cancer based on radiomics analysis and intraoperative frozen section: a retrospective study
Authors: Lv Xin , Lu Jing-Jing , Hou Yi-Ru , Song Si-Meng , Hu Yan-Jun , Yan Yan , Yu Tao , Ye Dong-Man
Published: July 2023

Purpose To evaluate the diagnostic efficiency among clinical model, radiomics model and nomogram that combined radiomics features and frozen section (FS) analysis for the prediction of lymph node (LN) metastasis for the patients with papillary thyroid cancer (PTC). Methods A total of 208 patients with PTC were retrospectively enrolled. The patients were divided into two groups randomly for training groups and validation groups. The Least absolute shrinkage and selection operator (LASSO) regression were used for the selection of radiomics feature extracted from ultrasound (US) images. Univariate and multivariate logistic analysis were used to select predictors including clinical characteristics and FS associated with the status of LN. The clinical model, radiomics model and nomogram were subsequently established. Results Multivariate analysis indicated that age, size group, Adler grade, ACR score and the psammoma body group were independent predictors to predict lymph node metastasis (LNM). The results showed that in the training group, nomogram had better performance than clinical model (P > 0.05) and radiomics model (P < 0.05). In the validation group, the results were similar to the training group, nomogram had a little higher diagnostic efficiency than clinical model (P > 0.05) and radiomic model (P > 0.05). Both in the training and validation group, nomogram had minor non-significant improvements in AUC compared to clinical model and significant improvements compared to radiomic model, however, the sensitivity of nomogram was a little higher. Conclusion We proposed that the nomogram combined the radiomics features and FS had the promise to create a substantial biomarker for predicting LNM of patients with PTC.