bluuebunny/crossref_metadata_2025 huggingface dataset:
PABPN1 functions as a downstream gene of CREB to inhibit the proliferation of preadipocytes
Authors: Zhang Xiao-Han , Li Jia-Xin , Wu Xiao-Xu , Zhang Qian , Tian Ming , Yang Si-Qi , Liu Di , Yang Xiu-Qin
Published: August 2024

Objective: This study was conducted to reveal the role of nuclear poly(A) binding protein 1 (PABPN1) in the proliferation of preadipocytes, and to reveal the relationship between PABPN1 and cAMP response element (CRE)-binding protein (CREB) in the regulation of preadipocyte proliferation.Methods: Vectors overexpressing and siRNAs against PABPN1/CREB were transiently transfected into both porcine preadipocytes and mouse 3T3-L1 cells. Preadipocyte proliferation was measured with cell counting kit-8, 5-ethynyl-2′-deoxyuridine, real-time quantitative polymerase chain reaction, Western blotting, and flow cytometry analyses. Additionally, the transcriptional regulation of CREB on PABPN1 were analyzed with dual-luciferase reporter gene and electrophoretic mobility shift assay.Results: Overexpression of PABPN1 inhibits, and knockdown of PABPN1 promotes, the proliferation of both porcine preadipocytes and 3T3-L1 cell lines. PABPN1 overexpression increased, while knockdown decreased, the cell population in the G0/G1 phase. These indicates that PABPN1 repressed preadipocyte proliferation by inhibiting cell cycle progress. Additionally, it was revealed that CREB regulated the expression of PABPN1 through binding to the promoter and that CREB inhibited preadipocyte proliferation by repressed cell cycle progress. Furthermore, we showed that PABPN1 functions as a downstream gene of CREB to regulate the proliferation of preadipocytes.Conclusion: PABPN1 inhibits preadipocyte proliferation by suppressing the cell cycle. We also found that CREB could promote PABPN1 expression by binding to a motif in the promoter. Further analysis confirmed that PABPN1 functions as a downstream gene of CREB to regulate the proliferation of preadipocytes. These results suggest that the CREB/PABPN1 axis plays a role in the regulation of preadipocyte proliferation, which will contribute to further revealing the mechanism of fat accumulation.
Effect of increasing β-mannanase supplementation in diets containing copra meal on growth performance, meat quality, liver health, intestinal morphology, and nutrient utilization in broiler chickens
Authors: Lee Eun Cheol , Kim Kang Hyeon , Kang Min Sung , Kim Deok Yun , Mugeniwayesu Charline , Kil Dong Yong
Published: August 2024

Objective: The current study aimed to investigate the effect of increasing β-mannanase supplementation in diets containing copra meal (CM) on growth performance, meat quality, liver health, intestinal morphology, and nutrient utilization in broiler chickens.Methods: A total of 1,600 3-d-old Ross 308 broiler chickens (initial body weight±standard deviation = 43.3±1.08 g) were randomly allotted to 1 of 5 treatment groups with 8 replicates. One group was fed a corn-soybean meal-based diet (control). Other 4 diets were prepared by inclusion of 10% commercial CM in the control diet with 0, 400, 800, and 1,600 U β-mannanase/kg. Experiments lasted for 32 d.Results: Birds fed the control diet had less (p = 0.001) feed conversion ratio (FCR) than those fed diets containing 10% CM without β-mannanase supplementation. Increasing supplementation of β-mannanase in diets containing 10% CM had no linear and quadratic effects on body weight gain, feed intake, and FCR in broiler chickens. The control diet had greater (p<0.01) apparent total tract retention (ATTR) of dry matter (DM), gross energy (GE), and N as compared to the diets containing 10% CM without β-mannanase supplementation; however, no differences in the ATTR of Ca and P were identified between 2 diets. There were no linear and quadratic effects of increasing supplementation of β-mannanase on the ATTR of DM, GE, N, Ca, and P in broiler diets containing 10% CM. Both inclusion of 10% CM and increasing supplementation of β-mannanase in broiler diets did not affect apparent metabolizable energy (AME) and N-corrected AME (AMEn) values in treatment diets.Conclusion: The use of 10% CM in broiler diets during growing and finishing period impairs growth performance by decreasing energy and nutrient utilization in diets. Increasing β-mannanase supplementation in diets containing 10% CM has no positive effects on performance, meat quality, liver health, intestinal morphology, and nutrient utilization in broiler chickens.
Porcine granulosa cell transcriptomic analyses reveal the differential regulation of lncRNAs and mRNAs in response to all-trans retinoic acid in vitro
Authors: Meng Jinzhu , Chen Xiuwen , Wang Huabiao , Mi Yixuan , Zhou Runsheng , Zhang Hongliang
Published: August 2024

Objective: The active metabolite of vitamin A, all-trans retinoic acid (ATRA), is involved in the proliferation and differentiation of granulosa cells, and promotes the follicular development, oocyte maturation, and ovulation in mammals. This study aims to investigate the ATRA induced potential long noncoding RNAs (lncRNAs) that regulate the expression of genes associated with granulosa cell proliferation and follicular development.Methods: The lncRNA and mRNA profiles of porcine granulosa cells from ATRA treatment and control group in vitro were constructed through RNA sequencing. Meanwhile, the sequencing data were verified using quantitative polymerase chain reaction (qPCR).Results: A total of 86 differentially expressed lncRNAs and 128 differentially expressed genes (DEGs) were detected in granulosa cells after ATRA treatment. The quantitative real-time PCR (qRT-PCR) results were consistent with the RNA-seq data. Functional annotation analysis revealed that the DEGs were remarkably enriched in ovary function and reproduction which contained FoxO, Hippo, Oocyte meiosis, mammalian target of rapamycin signaling pathway, as well as several pathways associated with hormone regulation like oxytocin signaling pathway and steroid hormone biosynthesis. Moreover, an interaction network of lncRNAs and their cis-target DEGs was constructed, and 7 differentially expressed lncRNAs and 6 cis-target DEGs were enriched in ovarian steroidogenesis and reproduction.Conclusion: These findings expand the lncRNA catalogue and provide a basis for further studies on the mechanism of ATRA-mediated lncRNA regulation of follicular development in pigs.
Legalization Of Islamic Principles (An Analytical Study Of The Maqashidi Interpretation Approach In The Book At-Tahrir Wa At-Tanwir By Thahir Ibn 'Asyur)
Authors: Anjaludin Anjaludin , Zen Abdul Muhaimin , Ulhaq M. Ziyad
Published: August 2024

The Qur'anic Maqasid in the verses that are almost formal in formalising Islamic Shari'a are as follows: Al-Baqarah/2: 208 emphasising the importance of entering the religion of Islam with its universal values that apply to all human beings. Al-Ma'idah/4:60 explains that taghut is a being other than Allah that is worshipped, and that it is important to obey the legitimate leader. Al-Ma'idah/5:44 gives the definition of disbelief as the disobedience of religious believers to the laws of the heavenly religions, while providing benefits to all humanity. Al-Ma'idah/5:45 and 47 indicate that zalim and fasik are terms for followers of any religion who do not follow the legal provisions of their holy book and do not provide benefits. An-Nisa/4:59 explains that ulil amri are leaders who are just, trustworthy and beneficial. Finally, An-Nisa/4:65 states that Muhammad's shari'a is a just Islamic shari'a and ijtihad law based on justice. All these verses represent the moral ideal of the Qur'an, which aims to fulfil the benefit of mankind and emphasises that the Qur'an is a relevant revelation for all time and place.
Educational Values For Children Based On Qs. Luqman: 13-14 In Digital Era?
Authors: Murharyana Murharyana , Al Ayyubi Ibnu Imam , Yasmin Sabrina , Riyadi Dede Ahmad , Maulana Cep Hasbi
Published: August 2024

This research aims to outline and explore the concept of educational values for children in digital era which is based on QS. Luqman: 13-14. The method used in this research is descriptive qualitative approach. Data collection techniques used observation and interviews. Data analysis techniques include data collection, data reduction, data presentation, and concluding. According to the results of this research, it is concluded that through the values ??contained in QS. Luqman: 13-14, bad deeds due to dehumanization and degradation can be addressed and prevented from an early age. The educational value of QS. Luqman verse 13 is to emphasize parents to keep their children away from acts of shirk and verse 14 is to emphasize for children to be good to parents and uphold gratitude. In this research, it can be concluded that the development of the digital era has greatly influenced human life to experience many significant changes. One of the changes occurs in children’s education which is assimilated with westernization and technology in it so that potential decadence occurs.
Intertextuality Of The Story Of Prophet Ayub In The Qur'an And The Bible (Julia Kristeva Semiotic Approach)
Authors: Irfani Muhammad
Published: August 2024

The stories of the prophets narrated by the Qur'an have mostly been explained in the Bible. each holy book in narrating the story of the prophet has its own purpose in conveying messages to its followers. Therefore, the stories of the prophets are important to be studied more deeply. This paper aims to analyze the differences in the narration of the story of prophet Ayub in the Qur'an and the Bible. This research uses qualitative methodology through the intertextual approach pioneered by Julia Kristeva in finding a comparison of the two scriptural narratives. This study concludes through the story of prophet Job contained in the Qur'an and the Bible that there is a reduction of narrative by the Qur'an which creates elements of haplology in each fragment. The suffering of prophet Job narrated by the Qur'an is the work of the devil. While the narrative told in the Bible is the devil. However, the general difference between the narratives of the two books is in terms of the themes raised. The Qur'an raises the theme of faithfulness and patience of Prophet Job, while the Bible carries the theme of suffering and piety of Prophet Job.
Ibnu Ashur's Interpretation On Qs. An-Nahl Verse 78 Regarding The Character Building Of Prenatal Children
Authors: Famela Sidney , Muhammad Hafid Nur , Mahdhor Muslich Marzuki
Published: August 2024

Prenatal character building reflects the importance of educating children well. Character education can start from the prenatal period in accordance with the Qur'anic verse in QS. Al-A'raf verse 172 which tells the story of fetal interaction with God during the allegiance. Although there is a view that prenatal children cannot be educated on the grounds of the verse QS. An-Nahl verse 78, but learning potential such as hearing and vision can be started early. This research studies the pattern of character building of prenatal children based on the perspective of tafsir at-tahrir wa at-tanwir by Ibn Ashur and its application in society. This research method is a literature study with a descriptive approach of tarbawi interpretation to understand the context of QS. The character building of prenatal children is directed to optimize the potential of as-sam'a, al-abshar, and al-af'idah as mentioned in QS. This involves the coordination of these three potentials to understand the science and nature of things so that children understand the right way to live. Based on the author's analysis, character education methods for prenatal children must pay attention to fundamental values such as al-fitrah, al-samahah, al-musawah, and al-huriyyah by using appropriate methods such as prayer, worship, reading, dhikr, dialogue, joint activities, and naturally conducive methods.
Exploring the Confluence of Financial Innovation, Human Resource Strategies, and Marketing Management: A Systematic Literature Review on Profit Maximization and Business Attraction
Authors: Djaharuddin Dharmawaty , Hasbiyadi Hasbiyadi , Syamsu Nur , Themba Orfyani S , Mochtar Susianah , Tafsir Muh.
Published: August 2024

This study aims to explore the intricate relationships between financial innovation, human resource (HR) strategies, and marketing management, and how their integration drives organizational success, particularly in terms of profitability and business attraction. Utilizing a systematic literature review, the research synthesizes findings from various academic sources to provide a balanced and comprehensive understanding of these interdependencies. The methodology focuses on analyzing the existing literature to identify the conditions under which financial innovation, HR strategies, and marketing management can be most effectively integrated. The results indicate that financial innovations such as fintech and blockchain significantly enhance organizational profitability when aligned with strategic HR practices and customer-centric marketing approaches. The study further reveals that the successful implementation of these innovations requires substantial investments in employee training and adaptive marketing strategies that resonate with consumer needs. The findings underscore the importance of adopting a holistic approach, where financial innovation, HR, and marketing are treated as interconnected components of a unified business strategy. This integration not only enhances competitiveness but also positions organizations to navigate the challenges of a rapidly evolving business environment. The study offers valuable theoretical and managerial implications, providing a framework for future research and practical guidance for business leaders and policymakers on leveraging these domains for sustainable growth.
Approaching Identity, Locality, and Community in Isotope Bioarchaeology
Authors: Turner Bethany L.
Published: August 2024

Each contribution to this special issue represents an emergent effort to explicitly situate isotopic research within the theoretical perspectives that inform, and increasingly underlie, other approaches within bioarchaeology. An ontological turn in social bioarchaeology has facilitated a proliferation of studies interrogating and reimagining key concepts like identity, mobility, personhood, and embodiment. However, as the editors of this issue note, isotope analysis has lagged somewhat behind this new wave of research. In this invited commentary, I review recent work in isotope bioarchaeology that engages with or informs these theoretical perspectives, focusing in particular on dynamic and intersecting themes related to identity, locality and foreignness, and community. In this analysis, I include a discussion of identity and community among bioarchaeologists, as we grapple with our disciplinary history of exclusion and exploitation and imagine the future of who we collectively are and how we do our work.
Cada una de las contribuciones a este número especial de la revista representa a un esfuerzo incipiente por situar explícitamente las investigaciones de isótopos estables dentro de las perspectivas teóricas que informan—y subyacen cada vez más—otros enfoques de la bioarqueología. Un giro ontológico en la bioarqueología social ha facilitado una proliferación de investigaciones que interrogan y reinventan conceptos claves como identidad, movilidad, y corporeidad. Sin embargo, tal como resaltan, los editores de este número, el análisis de isótopos se han quedado rezagados respecto a esta nueva oleada de estudios. En este comentario invitado, yo reseño estudios recientes de bioarqueología de isótopos que involucran o informan dichas perspectivas teoréticas, y me centro en temas dinámicos e interseccionales relacionados con la identidad, la localidad y la extranjería, y la comunidad. En este análisis, incluyo una discusión sobre las identidades y comunidades de les bioarqueóloges y su estado, mientras lidiamos con nuestra historia disciplinaria de exclusión y explotación e imaginamos el futuro de quiénes somos en tanto colective y cómo realizamos nuestro trabajo.
Mortuary Practices and the Importance of Rock-Shelters during the Early and Middle Holocene in the Southern Maya Mountains
Authors: Moes Emily , O'Donnell Lexi , Neff Nadia , Cerezo-Román Jessica , Trask Willa , Kennett Douglas , Prufer Keith
Published: August 2024

Research at two rock-shelters in the Maya Mountains of southern Belize, Mayahak Cab Pek and Saki Tzul, documents their persistent use as mortuary spaces over 9000 years, spanning the end of the last ice age until the end of the Classic period. These sites offer a rare diachronic view of mortuary behaviors within a single region of the neotropics spanning from early foragers through a long interval of transitional farmers. Here, we provide the first detailed discussion of human remains from these sites representing 30 burials dating between 12,000 and 3700 cal B.P. Analyses of burial features shows that communities in the region used diverse mortuary practices across this interval for the treatment and interment of their dead. These include primary burial, secondary burial, cremation, and possible disarticulation. All age categories are represented in the assemblage. Molecular data from aDNA and isotopes provide evidence of shifts in cultural behaviors and regional population structure. Despite these changes, mortuary treatments continue to be diverse throughout this time period, with no observable pattern or trend. However, all burials were recovered in two rock-shelters, representing unique features on the landscape. We examine and theorize the importance of these locations as mortuary spaces important to communities through time. We also explore evidence for the relationship between mourners, their dead, and these rock-shelters as precursors to later Classic Maya worldviews.
Ethik
Authors: Leonhardt Rochus
Published: August 2024

Ethik ist eine wissenschaftliche Disziplin, in der die Frage nach dem moralisch richtigen Handeln des Menschen erörtert wird. Obwohl sie also keine spezifisch theologische Wissenschaft ist, begegnet sie im Spektrum der theologischen Fächer als eine Teildisziplin der Systematischen Theologie. Dies liegt daran, dass der christliche Glaube auch eine lebens- und damit handlungsorientierende Bedeutung hat. Das Lehrbuch des Leipziger Theologen Rochus Leonhardt widmet sich in einem ersten Teil der Etablierung der Ethik als einer philosophischen Disziplin und fragt nach der Spezifik der theologischen Ethik. Ein zweiter Teil thematisiert zentrale biblische Bezugstexte und Leitbegriffe der christlichen Ethik und stellt maßgebliche Ethik-Typen vor. Der dritte Teil behandelt wichtige individual- und sozialethische Themen. Leitend ist dabei die Orientierung an den rechtfertigungstheologischen Grundeinsichten Martin Luthers.
Praktische Theologie
Authors: Karle Isolde
Published: August 2024

Das Lehrbuch bietet eine Gesamtdarstellung des Faches Praktische Theologie. Historische Perspektiven kommen dabei ebenso zur Geltung wie die Vielfalt aktueller Diskurse. Das Lehrwerk ist interdisziplinär angelegt. Fragen zu Religion, Identität, Lebensführung, Biographie, Kirche, Kommunikation und Gesellschaft werden sozialwissenschaftlich analysiert, bevor sie in einem theologischen Horizont gedeutet werden. Das Lehrwerk besteht aus zehn Kapiteln. Es beginnt mit einer Reflexion zum Selbstverständnis des Faches (1) und geht sodann der Funktion von Religion (2), Kirche (3) und Pfarrberuf (4) in der Moderne nach. Den Hauptteil bilden die großen Subdisziplinen der Praktischen Theologie: Homiletik (5), Liturgik (6), Poimenik (7) sowie die Theorie der Kasualien (8). Abgeschlossen wird das Lehrwerk durch Ausführungen zur Diakonie (9) und zur religiösen Medienkommunikation (10).
Religionswissenschaft und Interkulturelle Theologie
Authors: Wrogemann Henning
Published: August 2024

Das umfassende Lehrbuch ist in zwei Teile gegliedert. Der Teil Religionswissenschaft bietet einen Abriss der Religionsforschung von der Frühaufklärung bis zur Gegenwart. Dabei werden Ansätze von Religionsphilologie, -phänomenologie, -soziologie, -ethnologie und -ökonomie ebenso behandelt wie neuere Zugänge diskurstheoretischer, postkolonialer oder kulturwissenschaftlicher Religionswissenschaft. Dem schließen sich Grundinformationen zu Judentum, Hinduismus, Buddhismus und Islam in Geschichte und Gegenwart an. Im Teil Interkulturelle Theologie werden Übersichten zur christlichen Ausbreitungsgeschichte, zu Missionstheologien in Geschichte und Gegenwart, Formen Kontextueller Theologie sowie relevante Themen kirchlicher Praxis in verschiedenen Kontinenten geboten. Dem schließen sich Ausführungen zur Frage interreligiöser Koexistenz und Konkurrenz, zu Dialog und Zeugnis und der Entwurf einer christlichen Theologie interreligiöser Beziehungen an.
Rejuvenation of the Arabic Learning Paradigm: Considering Richard Rorty's Idea as an Alternative Education Discourse
Authors: Afif Amrullah
Published: August 2024

The purpose of this study is to show the educational aspects of Richard Rorty's thought that are linked to Arabic language education. This research is a type of document analysis that identifies and selects data in the form of text, then checks, sorts and evaluates the core concepts of Rorty's thinking systematically to be able to understand and interpret it in the context of learning Arabic. The research method used is literature research. Data analysis is carried out through three stages, namely data reduction, data presentation and conclusion drawn/verification. The results of the study show that Rorty's Paradigm of Thinking touches on several important aspects about the purpose and method of language teaching. In Rorty's view, the function of language as a means of communication, Rorty emphasizes the role of language as a tool for social interaction and conveying meaning. In language education, Rorty's educational paradigm challenges an approach that focuses on teaching rigid and normative grammar. In addition, he emphasized the importance of education as a social construction process where students not only learn language, but also develop their perspective on the world and the way they interact with others. Thus, Rorty's thinking in relation to language education emphasizes creativity, social and cultural context, as well as a growing understanding of language and meaning.
Penggunaan Media Pembelajaran Daring Masa Covid-19 di SMP N 1 Tomilito
Authors: Ritmon Amalah  , Hakeu Febrianto , Titin Suhartini Kaaba  , Yusuf Yayan D
Published: August 2024

Penelitian ini bertujuan untuk mengetahui penggunaan media serta kendala dalam pembelajaran daring masa Covid-19 di SMP N 1 Tomilito Kabupaten Gorontalo Utara. Metode penelitian ini adalah kualitatif. Adapun pendekatan penelitian adalah pendekatan pedagogis, yaitu pendekatan yang dilakukan untuk mengkaji persoalan-persoalan tentang suatu fenomena yang ada dengan berusaha memahami peristiwa-peristiwa dan kaitannya terhadap orang-orang yang terkait di dalamnya dan dalam situasi tertentu. Bedasarkan hasil penelitian menunjukkan bahwa, Penggunaa media Google Classroom sebagai media pembelajaran di SMP N 1 Tomilito sangat membatu dalam proses pembelajaran daring masa pandemi Covid-19 yakni dengan penggunaan media Google Classroom bisa memantau kegiatan-kegiatan belajar peserta didik, seperti absen, penjelasan materi dan pengiriman tugas-tugas yang diberikan secara online. Adapun perencanaan yang disusun guru dalam melangsungkan kegiatan pembelajaran daring ini tentu saja guru menyiapkan media pembelajaran. Untuk media yang digunakan guru, biasanya menggunakan media pembelajaran berupa video, gambar dan PPT. Dan kendala yang dihadpi guru dalam penggunaan media Google Classroom sebagai media pembelajaran di era Covid-19 bahwa jaringan yang kurang stabil, dan masih banyak peserta didik yang tidak memiliki smartphone serta lapto, masih adanya guru yang belum mahir dalam penggunaan media online sehingga berakibat kurang efektif guru dalam melakukan pembelajaran jarak jauh. Dan juga masih banyak peserta didik yang tidak mengerti cara menggunakan media online untuk pembelajaran. Hal itu berakibat kepada kemampuan daya serap belajar peserta didik yang kurang.
Epistemology Of Muhammad Iqbal's Existentialism:	Its Levation To Islamic Education
Authors: Haluti Rahmat , Munirah Munirah
Published: August 2024

The impoverishment of the philosophical dimension is taking place in this country, and the result, is then the economy becomes the main concern, life is no longer oriented to devoting oneself, guaranteeing the freedom of each individual as well as justice. The results showed that the socio-political and intellectual background of the environment and society influenced a lot of the construction existentialism of Mohammad Iqbal while Soren Kierkegaard was more influenced by the internal conditions of his family and life;  Mohammad Iqbal's construction existentialism is destiny, ijtihad, and self-concept, while Soren Aabye Kierkegaard is aesthetic, ethical, and religious; the similarity of the construction of existentialism Mohammad Iqbal and Soren  Kierkegaard lies in his similarity in critiques the thought that denies human individuality, Iqbal does a critique of Plato's idealism, while Kierkegaard does a critique of Hegel's idealism, the other similarity is to emphasize the importance of human individuality that demonstrates the true existence of human beings, basing their existential thinking on Existence God; the relevance of the existence of these two figures to Islamic studies is to make aware of the noble identity of man and needs to be maintained so as not to be trapped in materialism and moral impoverishment.
Kontribusi Pemanfaatan TIK Era Society 5.0 Terhadap Indeks Prestasi Mahasiswa Jurusan Pendidikan Agama Islam
Authors: Lestari Anugrah , Yasin Moh Fahri , Buhungo Ruwiah Abdullah
Published: August 2024

Penelitian ini bertujuan untuk mengetahui seberapa besar kontribusi pemanfaatan TIK pada era Society 5.0 terhadap pencapaian nilai indeks prestasi mahasiswa jurusan Pendidikan Agama Islam (PAI) di IAIN Sultan Amai Gorontalo. Jenis penelitian yang digunakan adalah penelitian kuantitatif dengan metode survey. Populasi pada penelitian ini adalah mahasiswa jurusan PAI IAIN Sultan Amai Gorontalo, Teknik pengambilan sampel menggunakan random sampling. Sampel penelitian adalah mahasiswa jurusan PAI Semester 2 dan 4 pada tahun ajaran 2022/2023. Teknik analisis data yang digunakan adalah analisis deskriptif dan inferensial berupa analisis regresi sederhana. Hasil penelitian menunjukkan kontribusi antara peanfaatan tik era society 5.0 terhadap hasil pencapain IP mahasiswa jurusan PAI memiliki hubungan yang signifikan dan tingkat hubungannya sedang dimana kontribusi sebesar 25,6%.
HUBUNGAN ANTARA UMUR DAN DUKUNGAN SUAMI DALAM PEMAKAIAN KB SUNTIKAN DI PMB ERLINA PALEMBANG TAHUN 2020
Authors: Agustina Rama
Published: August 2024

Paradigma baru program keluarga berencana Nasinal telah mengalami perubahan visi dari mewujudkan Norma Keluarga Kecil Bahagia dan Sejahtera (NKKBS) menjadi visi untuk mewujudkan “Keluarga Berkualitas tahun 2015” keluarga berkualitas adalah keluarga yang sejahtera, sehat, maju, mandiri memiliki jumlah anak yang ideal, berwawasan kedepan, bertanggung jawab, harmonis, dan bertaqwa kepada Tuhan Yang Esa. Dukungan keluarga dapat berupa informasi atau nasehat verbal dan non verbal, bantuan nyata, tindakan yang diberikan oleh keakraban sosial atau adanya perasaan bahwa kehadiran orang lain mempunyai manfaat emosional atau mempunyai peran terhadap perilaku bagi pihak penerima dukungan sosial. Kontrasepsi suntik adalah cara untuk mencegah terjadinya kehamilan dengan melalui suntikan hormonal. Diketahuinya hubungan antara umur dan dukungan suami dalam pemakaian KB Suntikan di Palembang tahun 2020. Metode penelitian/tahapan kegiataan (SOP) Desain Penelitian yang digunakan ini yakni observasional dengan pendekatan cross sectional. Populasi Seluruh ibu PUS yang menggunakan alat kontrasepsi suntikan di PMB Erlina. Sampel Total Sampiling. Lokasi penelitian dilaksanakan di Praktik Mandiri Bidan Erlina. Waktu penelitian dimulai pada bulan Juni - Agustus tahun 2020. Dari hasil perhitungan menggunakan uji Chi-Squre diperoleh P Value 0,004 < 0,05 maka dapat disimpulkan bahwa Ha diterima dan Ho ditolak, sehingga ada hubungan antara dukungan dalam pemakaian KB suntikan di PMB Erlina. Pada dasarnya dukungan dari suami/keluarga sangat diperlukan bagi pasangan usia subur untuk menuju keluarga bahagia. Simpulan dari hasil penelitian ini Bagi PMB. Penelitian ini diharapkan dapat memberikan pengetahuan tambahan. Bagi STIK Bina Husada penelitian ini diharapkan dapat memberikan sumber ilmu referensi diperpustakaan. Bagi peneliti diharapkan penelitian ini dapat menambah ilmu pengetahuan.
SEÇİM GÜVENLİĞİ BAĞLAMINDA YAPAY ZEKÂ TEKNOLOJİLERİ: GÜNCEL TARTIŞMALAR VE ÖNERİLER
Authors: Saitoğlu Furkan
Published: August 2024

Teknoloji alanında yaşanan gelişmeler siyaset ve kamu yönetiminde önemli değişiklikleri beraberinde getirmiştir. Özellikle dijitalleşmenin siyaset ve yönetim alanına yansıması avantajları ve dezavantajları da içerdiğinden ayrı bir öneme sahiptir. Gelişen teknolojinin siyasetin temel konusu olan seçim ve seçim güvenliğine etkisi tartışılan ve gelecekte de tartışılmaya devam etmesi beklenmektedir. Yapay zekâ teknolojisinin siyaset alanında kullanılması, seçimlerin her aşamasında etkinliğini artırması faydalarının yanında birtakım riskleri de taşımaktadır. Çünkü seçim sürecinin adil, şeffaf ve hesap verilebilir şekilde sağlanması siyasetin önemli bir konusudur. Seçim güvenliği sadece sandıkların korunmasından ibaret olmayıp, seçimin başlangıcından bitişine kadar geçen süreci ifade etmektedir.
Teknoloji ve siyaset tartışmasında yapay zekâ teknolojisinin hızlı ilerlemesi çok kısa zamanda siyasette bazı tehditleri de beraberinde getirmesi olasıdır. Seçim ve seçim güvenliği noktasında yapay zekânın etik şekilde kullanılmasını sağlamak için siyaset ve toplum ne yapmalı? Hangi önlemler alınmalı? Soruları önem arz etmektedir. Çünkü seçimlerin olmazsa olmaz ilkeleri olan etik, güven ve şeffaflık gereksinimi belirleyici rol oynamaktadır. Böylelikle siyaset ve toplum aktörleri yapay zekâ teknolojilerinin kötüye kullanılmaya hangi noktalarda açık olduğunu bilmesi zorunluluğu ortaya çıkmaktadır. Çalışmanın amacı yapay zekâ teknolojisinin seçim ve seçim güvenliği sürecinde yansımalarının nasıl olduğu, neye yol açtığı veya açabileceği, avantajları ve dezavantajlarının neler olduğunu, seçim güvenliğinde etik ve şeffaf anlayış çerçevesinde yapay zekânın etkilerini güncel tartışmalar üzerinden incelemektir. Ayrıca ek olarak Türkiye’de yapay zekâ teknolojisinin olası seçimlere yansıması ve ortaya çıkması muhtemel etik ve şeffaflık gereksinimi sorunlarına karşı nasıl reaksiyon vereceği üzerine çözüm önerileri sunmaktır. Bu çalışmada literatür taraması tercih edilmiştir. Sonuç olarak bu çalışma; yapay zekâ teknolojisinin seçim ve seçim güvenliğine yansımasını ele alarak, literatürde yeni ve eksik kalan alana katkı sunması beklenmektedir.
Cultivating the Values of Communication Ethics in Madrasah
Authors: Munifah Munifah , Syah Muhibbin , Muhtadi Asep Saeful , Natsir Nanat Fatah
Published: August 2024

this study is motivated by the current symptoms of moral decline, such as poor communication occurs among vulnerable adolescents with emotional traits. Many facts in society prove that wrong or incorrect communication will give birth to various immoral behaviors, fights, brawls, and various negative things that arise due to communication that does not care about ethics. This study uses a qualitative approach with descriptive analytical methods. The method of data collection in this study used in-depth interviews and supported by observation and documentation data. The results of this study indicate that: planting the value of communication ethics in the four MTs Banjar has been done through polite, courtesies, and greetings, both inside and outside the madrasah. So that it becomes a daily habit with the aim to improve the morale, and mental learners but not maximal. Therefore, instilling an understanding of communication ethics to students is very important so that they know how good communication ethics when communicating in terms of behaving and speaking appropriately.
The Influence of Health Education Using Brainstorming Method About Exclusive Breastfeeding on Breastfeeding Mother's Knowledge in PMB D Bogor District in 2023
Authors: Azizah Zulfa Nur , Noviana Ekki , Munah Fauzul
Published: August 2024

Health education is expected to increase the knowledge of breastfeeding mothers in exclusive breastfeeding. West Java Health Profile in 2017 the coverage of exclusive breastfeeding in Bogor Regency was 22.84%. Mother's knowledge can influence exclusive breastfeeding. To determine the effect of health education using the brainstorming method about exclusive breastfeeding on the knowledge of breastfeeding mothers at PMB D Bogor Regency in 2023. This study used a one group pre-test post-test pre-experimental research design. Analytical research method with cross sectional design. Total population of 35 people with a sample of 32 people. The sampling technique used was purposive sampling, and bivariate data analysis used the assisted t-test. The results of the univariate analysis showed that the respondents were aged 20-35 years (84.4%), high school (78.1%), housewife (90.6%), the knowledge of breastfeeding mothers before being given health education using the brainstorming method was mostly lacking (43.8%), the knowledge of breastfeeding mothers after being given health education using the brainstorming method was mostly good (65.6%). The results of the bivariate analysis showed that there was an effect of health education using the brainstorming method about exclusive breastfeeding on increasing the knowledge of breastfeeding mothers with a p-value of 0.000 <0.05. There is an effect of health education using the brainstorming method about exclusive breastfeeding on increasing the knowledge of breastfeeding mothers.
Permasalahan dan Peluang Perkembangan UMKM melalui Pencatatan Akuntansi Perusahaan Tahu Kamal, Bangkalan
Authors: Akbar Ari , Ilfah Farrah Noor Aminah , Malikhah Nila , Ummah Vina Rohmatul , Adiyanto Mochammad Reza
Published: August 2024

Dunia bisnis menghadapi persaingan pasar yang semakin intens. Di tengah pasar yang sibuk dan terus berubah, perusahaan harus berjuang untuk terus menonjolkan produk unggulan yang akan memberikan keunggulan tersendiri untuk produk yang telah dibuat. Tujuan dari penelitian ini adalah untuk mempelajari cara-cara akuntansi yang dapat digunakan untuk menghitung perputaran keuangan yang terus berkembang dari suatu bisnis. Data dikumpulkan melalui wawancara dan penelitian ini dilakukan dengan metodologi kualitatif. Perusahaan tahu di Kamal, Pulau Madura, adalah subjek penelitian ini. Hasil menunjukkan bahwa lokasi perusahaan tahu di Kamal, Pulau Madura, sangat strategis, dan harga yang ditawarkannya menarik dan terjangkau. Apabila produk tahu dijual kepada masyarakat, masyarakat juga akan membelinya dengan harga yang terjangkau, dan layanan konsumennya juga ramah. Sementara itu, perusahaan tahu Kamal di Pulau Madura memiliki kelemahan: tempat yang tersedia untuk membangun dan menjalankan bisnis sangat terbatas, dan penjualan produk tahu hanya terbatas pada orang-orang di sekitar mereka yang membeli. Selain itu, melihat dan menerapkan pembukuan akuntansi dalam keuangan suatu perusahaan akan membantu dalam pengambilan keputusan. Bisnis dapat mencapai tujuan mereka dan menemukan kekurangan mereka melalui penelitian dan strategi kompetitif.
INFLAMMATORY RENAL PSEUDOTUMOR IN WEGENER'S GRANULOMATOSIS: INITIAL MANIFESTATION OF A CASE
Authors: Pereira-Correia João Antonio
Published: August 2024

We report a case of a 37-year-old woman who was treated in the emergency department with low back pain and intermittent cough for 7 days. Computed tomography and magnetic resonance imaging of the abdomen and pelvis revealed an expansive, heterogeneous formation with ill-defined limits, measuring 6.3 x 5.1 cm, in the upper third of the left kidney and a second expansive formation located in the lower pole of the left kidney, measuring 5.1 x 5.9 x 6.4 cm. She then underwent uneventful left videolaparoscopic radical nephrectomy. After the procedure, the patient progressed with prostration, decreased general condition and cough with brownish secretion, in addition to complaining of decreased visual and hearing acuity. She underwent laboratory and imaging tests, revealing bilateral cavitated lung masses that proved to be a case of Wegener's granulomatosis. Treatment with pulse therapy was initiated, but the patient died days later. This is the 11th case described in the scientific literature and serves as a warning to guide the management of this rare clinical condition, especially with regard to the presentation of inflammatory renal pseudotumor.
Patients’ satisfaction with surgical services in a tertiary hospital: A cross-sectional analytical study
Authors: Ogoronte  A. Ijah Rex Friday
Published: August 2024

Patients’ satisfaction with health services is partly shaped by the prevalent quality of such services in that locality, cultural values, and the year in health service development. The aim of this study was to evaluate the degree of patients’ satisfaction with the surgical services rendered at the Surgery Department of the Rivers State University Teaching Hospital in February of year 2024. A cross-sectional analytical study was carried out among all consenting patients who access surgical services at the Rivers State University Teaching Hospital. There were 220 (56.4%) male respondents and 170 (43.6%) females, with a mean age of 43.2±16.3 years. Majority of the respondents were satisfied (average, good and excellent) with the core surgical services (94.1%) and surgical support services (100%). The cumulative overall patients’ satisfaction for both core surgical and surgical support services was 99.2%. A statistically significant positive relationship was found between the degree of satisfaction with core surgical services and technical competencies of staff, respect and good handling, ease of access, good services, and cost of surgical services. An overall above average level of patients’ satisfaction is reported in this study, and some areas of improvement were identified. The cost of surgical services, technical competencies of staff, and respect and good handling, were the most dominant reasons that shaped patients’ satisfaction.
Pediatric Citrobacter Urinary Tract Infections: A Case Report Highlighting Emerging Trends
Authors: Acevedo Hector
Published: August 2024

Urinary tract infections (UTIs) caused by Citrobacter species in pediatric patients present a unique and infrequently reported scenario in clinical practice. This case report delves into the clinical presentation, diagnostic challenges, treatment modalities, and overall management of a pediatric UTI caused by Citrobacter. Through a literature review, it becomes evident that while Citrobacter infections are more commonly observed in adults, especially the elderly population, recent studies signal a rising trend in pediatric cases globally. Noteworthy findings from published cases underscore the diverse clinical manifestations and associated challenges. We present the case of a 1-month-old male who presented with feeding difficulties and irritability, subsequently diagnosed with a UTI caused by Citrobacter koseri. Despite lacking typical risk factors or symptoms associated with Citrobacter UTIs, the patient demonstrated a favorable response to antibiotic therapy. This case stresses the evolving nature of Citrobacter infections in the pediatric population and emphasizes the importance of vigilance in recognition and management. Further research is warranted to better understand this emerging trend and its implications for pediatric care.
Capacity Of The President Of The Republic In Relation To The National Parliament And The Government Of Timor-Leste (2024)
Authors: Corte-Real de Araújo Alexandre Gentil
Published: August 2024

Introduction: The President of the Republic is the Head of State, symbol and guarantor of national independence, the unity of the state and the regular functioning of democratic institutions under the terms of paragraph 1 of article 74 of the CRDTL, the President of the Republic through his constitutional powers provided for in clause F) of article 86 of the CRDTL, with the President of the Republic to dissolve the National Parliament in the event of a serious constitutional crisis that does not allow the formation of the government or the non-approval of the General State Budget.
Fracture Embarrure Du Crane Aspect Epidemiologique, Cliniqueparaclinique Et Therapeutique A Propos De 48 Cas Au Centre Hospitalier Regional De Ziguinchor
Authors: Diakaoe Sambou natacha Maria
Published: August 2024

Introduction : Les embarrures sont des lésions représentées par un enfoncement d’un ou de plusieurs fragments osseux de la boite crânienne. Cette étude avait pour objectif de décrire l’épidémiologie, les mécanismes lésionnels, la clinique et d’évaluer les résultats de la prise en charge des fractures embarrures au service de neurochirurgie du centre hospitalier régional de Ziguinchor.
High Protein Kinase B (Akt) Concentration in Attention Deficit Hyperactivity Disorder
Authors: AJ Russo
Published: August 2024

Attention-deficit hyperactivity disorder (ADHD) is characterized by inattentiveness, hyperactivity, and impulsivity. It has been suggested that the mTOR pathway, which downstream includes activation of Akt, is involved in ADHD. In this study we measured the concentration of phosphorylated Akt in 55 ADD patients and 32 neurotypical controls using an ELISA. We found that Akt levels were significantly higher in the ADD group and may be important to the etiology of ADD/ADHD.
Mental Activity And Psychosomatic Expressions In Digital Times
Authors: Rocha Martinez Tania Leme da
Published: August 2024

Mental activity and its psychosomatic repercussions are influenced by the prevailing culture, which is currently very much related to internet articles. The mechanism is the same, but with nuances of stimulation of the thoughts, of origin of the facts of contemporaneity. Affection is of paramount importance in the formation of thought. The mother without the ability to reverie would hinder the alpha function and thus disturb the emotion and the formation of thought - this is the importance of the first mold period. Affection unites with unconscious ideas and fantasies. Since the unconscious fantasies are psychic representatives of instinct, once connected with the unconscious ideas, they would have the manifestations of the affective state. This would be perceived thanks to the pleasant and unpleasant sensations. Probably the greatest contribution to the notion of an organic thought is that constituted by the conjugation of the theory of thought with the theory of instincts and with the theory of affects. The formation of symbols, by projective identification, gives rise to symbolic equations that result in a concrete thought and in the idea that the formation of the true symbols available for sublimation and communication depends on the elaboration of the anguish of depression. The symbol is concretely assimilated with the symbolized object. The symbolic equation is the complete assimilation of the symbol, which is a part of the body, with the symbolized. Nowadays the peculiarity is the cyber effect on behavior, the ideas that arise from internet communications in various senses, either good or bad. In conclusion, thinking and imagination can lead to symptoms and demonstrate what it is like to speak in each body.
Application SF 36 And EQ 5D To Assess Quality Of Life In Musculo-Skeletal Health Of Elderly Patiens To Determine Intervention: Systematic Review
Authors: Dewi Desak Wayan Suarse Dewi , HASSAN HAFIZAH CHE HASSAN , NAMBIAR NISHA NAMBIAR
Published: August 2024

Background: Elderly Patients which  chronic Kidney Diseases on Haemodialysis (HD) experience impaired muscle strength related quality of life (QoL). We analysed HD  relationship with physical performance, body composition, and muscle strength; Purpose: To asses QoL in muscle-skeletal health and functional Capacity on elderly Chronic Kidney Diseases maintenance Haemodialysis. Methods: Using systematic literature review with data base EBSCO, ELSIVIER, Pup Med, Science Direct, Walley, start search year 2020-2023, 13 articles Randomize control trial and cross sectional. Groups underwent the following assessments physical QoL using application of the SF-36 questionnaire , and the Euro QoL five item psychologic-questionnaire (EQ-5D) are two of the most popular.  Observed 6-minute walk test (6MWT) and handgrip strength, one-repetition maximum of knee flexors and extensors. Result: Main approaches, namely generic and disease-specific instruments, can be applied to measure health-related quality of life, the short form 36 questionnaire (SF-36) and the Euro QoL five item questionnaire (EQ-5D) are two of the most popular. One of the main goals of any interventions to prevent and cure musculoskeletal problems in the ageing population with should be to improve quality of life. Conclusion: To measure health-related quality of life, two basic methods can be used: The EQ-5D and the short form 36 questionnaire. Overview surveys are used to measure the quality of life related to health in individuals suffering from musculoskeletal illnesses. The validation of therapeutic and preventive interventions in this field should be aided by the recent development of specific instruments.
Endodontic Microsurgery Using Dynamic Navigation and Trephine Burs
Authors: Nick Sanders Jeffrey , Smith Trenton , Jain Sameer , Block Michael , Odom Mark A. , McMullen Albert F.
Published: August 2024

Objectives: The use of the surgical operating microscope, CBCT imagining, biocompatible filling materials and ultrasonic instruments have improved the success and predictability of apical surgery. Despite these advances, more accurate and precise techniques for creating osteotomies and root-resections (apicoectomies) have not been widely adopted. This study highlights how dynamic navigation systems (DNS) can help avoid unnecessary dentin removal and “mitigate iatrogenic errors” such as root perforation. Methods: A total of 56 root-end resections were planned and completed on two sets of identical TrueJaw Endosurg models (DE Labs, Santa Barbra, CA, USA). One set of maxillary and mandibular jaws were used for 28 preparations, performed with a DNS (X-Guide, X-Nav Technologies, Lansdale, PA, USA). A second set of maxillary and mandibular jaws were used for 28 preparations executed freehand (FH), with pre-op measurements taken from a CBCT scan (CS 9600; Carestream, Atlanta, GA, USA). A Mann-Whitney test was used to compare the accuracy of the two groups Results: The average preparation depth was 10.77 mm. For the DNS group the average angular deviation was 2.35 degrees. The average deviation at the terminal end of the preparations was 0.96 mm (global apical deviation). For the freehand group average angular deviation was 13.55 degrees and the average global apical deviation was 2.62 mm. Significant differences were identified between the DNS and FH groups for angular deviation (p<0.05), apical non-depth deviation (p<0.05) and between the Global apical deviation(p<0.05). Conclusion: Dynamic navigation demonstrated superior accuracy and precision over freehand in the context of apical microsurgery preparations. This study provides further proof of concept for the application of DNS in Endodontics. Clinical significance: Apical surgery can be a daunting task for an endodontist. Surgical guides can make the procedure easier, but they take time and money to make. DNS virtual planning can be completed rapidly and may be altered mid-procedure. This inherent flexibility makes same-day guided apical surgeries practical and predictable.