bluuebunny/crossref_metadata_2025 huggingface dataset:
O urbano no Rio Grande do Norte: uma realidade diversa
Authors: Gomes Rita de Cássia da Conceição
Published: September 2017

O presente artigo tem por objetivo compreender a fragmentação do território na perspectiva político-administrativa e a dinâmica de formação de cidades no Rio Grande do Norte - RN e, por conseguinte mostrar o urbano que se apresenta decorrente dessa fragmentação. O trabalho se apoia na ideia de que o território potiguar se fragmentou sob a influência de duas dinâmicas bem definidas: uma atrelada às economias tradicionais quais sejam: cana-de-açúcar, pecuária e agricultura; e outra política, articulada aos interesses de oligarquias e grupos políticos locais que usaram o processo de criação de municípios para estabelecerem seus territórios eleitorais. As reflexões expostas no texto resultaram do diálogo empreendido com a bibliografia atinente ao tema, bem como com autores que versam sobre a realidade do RN e ainda do resultado de pesquisas que realizamos no contexto da academia. Os resultados da pesquisa colocaram em evidência que o processo de fragmentação do território apoiada nos vetores assinalados produziu uma malha urbana diversa, marcada pela presença de um número expressivo de cidades com menos de vinte mil habitantes, de poucas cidades com funções intermediárias que assumem papeis importantes no contexto urbanorregional, e a presença de duas centralidades representadas por Natal, capital do RN e por Mossoró, a segunda maior cidade, localizada no oeste do estado. No entanto, esta configuração da malha urbana potiguar não inibiu a emergência de uma realidade urbana que, por meio de práticas sociais e espaciais desenvolvidas, articula-se à reprodução do mundo contemporâneo enquanto totalidade.
Les ambassadeurs du roi de France d’origine étrangère sous les deux premiers Bourbons, 1589-1643
Authors: Gellard Matthieu
Published: September 2017

Alors que les étrangers représentaient encore 18 % des ambassadeurs sous les derniers Valois, ils ne sont plus que 12 % parmi ceux qui servent les deux premiers Bourbons. Cette décroissance peut être mise en relation avec le mouvement qui voit l’exclusion des étrangers de la cour de France à partir des années 1580. En observant de plus près l’origine des étrangers au service d’Henri IV et de Louis XIII, il est possible de noter la quasi-disparition des Italiens, qui représentaient le contingent le plus important entre 1559 et 1589. À l’exception de quelques Allemands et Lorrains, ce sont désormais les Cantons suisses qui fournissent la majeure partie des étrangers en service dans la diplomatie française ; sans eux, la francisation de celle-ci serait presque complète. Ces Suisses ont cependant un profil bien particulier puisque ce sont essentiellement des soldats, au service de France mais aussi souvent de leur canton d’origine, qui ne s’installent pas en France et ne demandent pas leur naturalisation. Avec eux, les représentants d’origine étrangère sont par ailleurs majoritairement cantonnés à des missions peu prestigieuses, souvent en lien avec leur origine géographique.
Analyzing Foreign Investors Behavior in the Emerging Stock Market: Evidence from Qatar Stock Market
Authors: Elsiefy Elsayed , AbdElaal Moustafa Ahmed
Published: September 2017

This paper examines the effect of the foreign investors fund flow into the domestic stock market. We investigated whether foreign investors are only herders or if they have also the ability to push the market up and down. To answer this question, we include investors’ types as an independent factor in Markov-Switching Model used by Hamilton (1989) to examine the asymmetric effect of the foreign investors during the bull and bear states. Empirical results from Qatar Stock Market suggested that foreign institutional traders are only herding in the market and they cannot play the role of the market maker. We have also found that neither foreign investors nor domestic investors have the ability to switch the regime of the market. The time-varying relationship between the various investors’ types has been investigated. We reported that, although the correlation matrixes of the investors’ categories with the market are time-varying, the foreign institutional trader is still the leader of the market during the bull (bear) states of the market. Finally, we proposed some procedures to minimize the harmful of the foreign investors bad trading.
Reviewer Acknowledgements for Applied Physics Research, Vol. 9, No. 5
Authors: Green Lily
Published: September 2017

Reviewer Acknowledgements for Applied Physics Research, Vol. 9, No. 5, 2017
Analysis of an Authentic Historical Italian Cosmetic Talc Sample – Further Evidence for the Lack of Cancer Risk
Authors: Ilgren Edward B. , Sartorio Carlo , Hoskins John
Published: September 2017

Italian talc from the Pinerolo Mines in North West Italy is known for its extreme purity. Several historical investigations of these mines have demonstrated very small amounts of tremolite in the host rock that occasionally found their way into the mined ore. However, more than sixty years of epidemiological studies of the Pinerolo miners and millers have failed to demonstrate any attendant cancer risk and show that this trace tremolite contamination is of no biological significance.Claims made that the Pinerolo Italian cosmetic talc produced prior to 1975 were contaminated with asbestos, principally tremolite, have been difficult to refute given the lack of authentic historical samples of commercial products. We now describe the analytical findings of a recently discovered authentic historical sample.Sample analyses of this material showed only a few non-asbestiform tremolite fibres - a finding discussed in the light of the historical (pre-1975) studies of this talc deposit: no serpentine (chrysotile) or amphibole fibres were detected.The numerical concentration of tremolite fibres in the talc sample was 3.687 x 106 fibres/gram, corresponding to a mass concentration of 0.722 parts per million.
Reviewer acknowledgements for Environment and Pollution, Vol. 6, No. 2
Authors: John Albert
Published: September 2017

Reviewer acknowledgements for Environment and Pollution, Vol. 6, No. 2, 2017.
Reviewer acknowledgements for International Journal of English Linguistics, Vol. 7, No. 5
Authors: Xu Diana
Published: September 2017

Reviewer acknowledgements for International Journal of English Linguistics, Vol. 7, No. 5, 2017.
Examination of the Relationship between Luxury Value Perception and Shopping Motivations: Turkey Sample
Authors: Kurnaz Aysel
Published: September 2017

It was aimed to reveal the effects of financial, functional, individual and social value perceptions on hedonic and utilitarian shopping motivations within this study. In this direction, a questionnaire was conducted to people over the age of 18 in cities representing 12 regions of Turkey and 2857 questionnaires were put into consideration in total. Confirmatory factor analysis and structural equation modelling (SEM) were applied to data. According to findings it was identified that the luxury value perception has influence over hedonic and utilitarian motivations. The individual value dimension of luxury perception has the highest effect on hedonic motivations and social, financial and functional value dimensions follow it respectively. And the relative effect of functional luxury value perception also has the highest effect on utilitarian motivations and the financial, individual and social values follow respectively. It was found that, while all these perception’s effects have positive impacts, only the social value perception has a negative impact on utilitarian motivations.
Reviewer Acknowledgements for International Journal of Marketing Studies, Vol. 9, No. 5
Authors: Xiao Maple
Published: September 2017

Reviewer acknowledgements for International Journal of Marketing Studies, Vol. 9, No. 5, 2017.
Assessing the Impact of Relationship Length in the SMEs and Bank Association
Authors: Ojeme Mark
Published: September 2017

Despite the importance of satisfaction, loyalty and relationship length in the literature, there is very little evidence of studies within the Nigerian Business to Business (B2B) Relationship terrain. This paper seeks to investigate the effect of relationship length on SMEs association with their banks in Nigeria. Measurement Items were adapted from various scale sets presented in existing studies were combined to investigate the B2B relationship context. Data were collected from 221 SMEs via a self-administered questionnaire completed either by the SME owner or senior manager with responsibility for relationship with their bank, providing 199 usable records. Principal Component Exploratory Analysis (PCA) was used to determine the underlying data structure, with subsequent deployment of Cronbach’s alpha as a post-hoc assessment of the internal reliability of the retained factors. Subsequently, regression analysis was employed to determine the impact of satisfaction on loyalty in a short and long term relationship contexts. The analysis presented suggests that the SMEs’ had evidence of been satisfied with their bank, however, the regression analysis for both short and long term relationship length were both significant in impacting their loyalty towards their bank. The originality of this paper lies in the investigation of a B2B relationship involving SMEs and banks within a relationship context that hitherto was unknown and the validation of relevant relationship building blocks.
Italy’s Image as a Tourism Destination in the Chinese Leisure Traveler Market
Authors: Gravili Silvia , Rosato Pierfelice
Published: September 2017

This study aims to measure the image of Italy as a tourism destination on the Chinese leisure traveller market. To this end, Echtner & Ritchie’s model (1991) is applied; however, compared to its original formulation, it is implemented with greater consideration of the experiential dimension and potential travel constraints affecting the perception of the range of tourism goods and services on offer. This enables not just a denotative, but also and above all a connotative measurement of the image, thereby reducing the risk of ambiguity in the interpretation of the most significant attributes that emerged during the analysis. Adopting a hypothetical segmentation of the market in question, it was also possible to the elements that act as encouraging and discouraging factors regarding a holiday in Italy are highlight, identifying tailor-made approaches to the construction and promotion/commercialisation of tourism products designed to be attractive to the specific segment of interest.
Sponsoring Sports Teams with Low Media Exposure: An Exploratory Investigation on Small and Medium Sized B2B Firms
Authors: Konstantoulaki Kleopatra , Rizomyliotis Ioannis , Giovanis Apostolos , Conti Vittorio , Kallandranis Christos
Published: September 2017

The current research was designed to further comprehend the nature of the relationship between small and medium-sized sponsoring enterprises and their affiliated sport organizations. In order to achieve this purpose, the research has involved some of the major sponsors of Italian rugby teams that participate in the Championship that has limited media exposure. Using semi-structured interviews the study focused on understanding what managers think of sponsorship and exploring the underlying reasons in a small business decision to sponsor a sport team with poor or limited media visibility. Results show that the involvement of local firms in the city’s activities is very important. When sponsors exploit these forms of sponsorship as a way of helping the local community, then they seem to adopt these sponsorships to reach an effective outcome in terms of brand awareness and return on investment. Conclusions are discussed and recommendations are offered.
The Process of Retail Internationalization in the Chinese Market: A Case of Japanese Fashion Company
Authors: Miao Miao
Published: September 2017

Since China’s ingress into the World Trade Organization (WTO), to a greater extent, multinational business enterprises have entered the market. Fashion industries, for instance, led by European and American apparel retailers, including many Japanese companies, have begun to pay attention to the Chinese market. This is embodied in diverse formats of retailing outlets with international expansions. The intent of this paper is to present an empirical study for improving the framework of retail internationalization processes in the Chinese market, and to provide a perception of the interface between retailing and building customer relationship. Case studies approach is employed in this study to build theories. The objectives of this research are (1) to investigate the processes and barriers of entering the Chinese market by looking at a case study of a Japanese fashion retailer; (2) to clarify the characteristics of each stage of international expansion by applying dynamic capabilities based on a framework that makes a distinction between a firm’s first stage, second stage and third stage; and (3) to indicate the emergence of a new retail format, called a “house brand store,” and its important role in retail internationalization and customer relationship management.
Reviewer acknowledgements for Journal of Materials Science Research, Vol. 6, No. 4
Authors: Green Lily
Published: September 2017

Reviewer acknowledgements for Journal of Materials Science Research, Vol. 6, No. 4, 2017
Impact of Weather Index Insurance on Groundnut Farmers’ Technical Efficient in Senegal: A Propensity Score Matching Approach
Authors: Atozou Baoubadi , Lawin Kotchikpa Gabriel , Niang Diombare
Published: September 2017

Irregular and low rainfall levels and drought have become important sources of low agricultural yields and agricultural incomes in sub-Saharan Africa. Weather index insurance is a financial product for climate risk management aimed at securing farmers' incomes. This paper aims to evaluate the impact of a weather index insurance project piloted with groundnut farmers in Senegal in 2015-2016 agricultural season on farmer’s technical efficiency (TE). A Stochastic Production Frontier model was used to estimate the TE scores. A matched group of beneficiaries and control farmers was determined using propensity score matching techniques to mitigate biases stemming from observed variables. The results showed that average TE is consistently higher for control farmers than the beneficiary group. Age, gender and education were found to be significantly related to technical efficiency, while membership in farmers’ association, credit, improved seeds and extension contact were not significantly related to technical efficiency. From a policy perspective, we suggest that weather index insurance programs targeting smallholder farmers in developing countries, and particularly in sub-Saharan Africa, be accompanied with education services, provision of new technologies such as high yield seeds and other best farm management practices and credit to help farmers better adapt to weather shocks and secure their production and income.
A Quantitative Nexus Approach to Analyze the Interlinkages across the Sustainable Development Goals
Authors: Karnib Ali
Published: September 2017

The 2030 Agenda for sustainable development comprises 17 Sustainable Development Goals (SDGs) that aimed at achieving universal access to basic needs and services for all. Moreover, the SDGs present a broad and comprehensive set of goals that cover social, economic and environmental aspects. The global SDGs are interlinked and they are either mutually supportive or conflicting. Informing about the interlinkages enables policy makers to harness synergies and manage any potential conflicts between policies engaged to achieve the SDGs. This paper introduces a framework to analyze interlinkages across the SDGs based on a bottom-up process which is supported by a quantitative nexus theoretical method to evaluate the direct and indirect quantitative interactions among SDG variables. Firstly, the general concept of analyzing interactions based on a bottom-up process is presented. Secondly, a quantitative nexus method based on input-output theory that permits the evaluation of the direct and indirect interaction effects among SDG variables is introduced. Lastly, a numerical experiment is presented and results are discussed.
Tradition of "Falia" Local Wisdom as Cultural Capital in the Formation of Magnanimity of Muna Society
Authors: Taena La , Laepe Ader , Basri La Ode Ali , Miliha La , Lio Asrun , Suardika I Ketut
Published: September 2017

The tradition of 'falia' is the cultural local wisdom of the Muna community, as a specific culture is explored from their life experiences from generation to generation in the past. 'Falia' is a prohibition that cannot be violated either individuals or groups. However, it has been eroded by the era of globalization lately and its generation is slowly forgetting it, whereas the meaning of 'falia' has a universal humanism value, pedagogic which is used as a guide to create harmony and social order, has noble character.The purpose of this study is to describe and analyze (1) forest preservation, (2) sex education, (3) respect for work performance of others, (4) work ethic, (5) ethics. The method used in this research is designed descriptively qualitative; located in Muna District; data collection is done by observation, interview and documentation. Data analysis technique is used by data reduction, data presentation, conclusion and verification. The results of this study found in the field are (1) advocating to conserve forests, (2) to avoid free sex, (3) to appreciate the services and works of others, (4) the Muna community is very tenacious, diligent, steadfast, and high work ethic, (5) they have good manners and ethics.
How International Law Can Deal with Lack of Sanctions and Binding Targets in the Paris Agreement
Authors: Okonkwo Theodore
Published: September 2017

The Paris agreement aims at strengthening how the global community has responded to the change in climate by forming international government bodies that would be committed to reducing emissions to the environment. The lack of sanctions and binding targets in the Paris agreement has made its implementation difficult because countries live in an anarchical scenario where there is no overarching body. The agreement was drafted in November 2015 and signed on 22nd April 2016 by 196 countries but since then the success of the agreement has been in question. Generally, the treaty aims at controlling climate change and this is one of the areas that has been so difficult to control. Climate change is a tricky area to tackle because the developed countries are high pollutants because of the industries. The developed countries are mostly the ones who drive the agenda of the Paris treaty because they have the force and resources to do so. They influence policies and the decisions made. Therefore, the lack of sanctions and binding targets makes the treaty difficult to implement because there are no punishments as such. International treaties are difficult to implement especially when there are no sanctions or binding targets. As an example of international treaty governed by international law, it means that the treaty has loopholes that can be targeted by member states not to comply when the provision does not favour them. This paper critically analyzes how international law can deal with the lack of sanctions and binding targets in the Paris agreement as it operates in the international arena.
Cost and Time Overruns in Building Projects Procured Using Traditional Contracts in Nigeria
Authors: Kadiri Dele S. , Onabanjo Babajide O.
Published: September 2017

The traditional contract procurement system is reported to be the most preferred in Nigeria for the execution of construction projects. However, the system has been criticised to be ineffective in terms of both cost and time performances. Owing to scanty empirical evidence to support this claim, this study assessed cost and time overruns in building projects executed in Nigeria using the system. Schedule and cost data of building projects were accessed from randomly selected frontline quantity surveying firms in the study area. These comprised schedule data on 51 public and 41 private building projects as well as cost data on 42 public and 33 private building projects. The data were analysed using frequency, percentage and mean. The findings from the study revealed that both public and private building projects executed in the study area using traditional contract system experienced cost and time overruns to varying degrees. However, the system was more effective in terms of cost performance than time performance.
El Nino-Southern Oscillation Influences on Food Security
Authors: Muza Olivia
Published: September 2017

El-Nino Southern Oscillation (ENSO) is the most recurrent change in climate impacting agriculture productivity and food security. This study investigates ENSO impacts on four cereal crops (maize, millet, sorghum and wheat) using crop production and climate datasets spanning the years 1960-2015. The results of this study reveal that during El Nino (La Nina) maize, sorghum and wheat production decreases (increases) while that of millet increases (decreases). Even though, the correlation is statistically significant for maize only, the outcome is a call to review the macro-food policy taking into account ENSO-related phase effects to redress food insecurity. The study recommends incentives for agricultural productivity including irrigation intensification and small grain value chain development, trade and food security arrangements, income generation opportunities and strategic partnerships for improved food and nutrition security.
Reviewer Acknowledgements for Journal of Sustainable Development, Vol. 10, No. 5
Authors: Sun Sherry
Published: September 2017

Reviewer Acknowledgements for Journal of Sustainable Development, Vol. 10, No. 5, 2017
Clean Cane Production Techniques and Environmental Sustainablility: A Review
Authors: Doorasamy Mishelle
Published: September 2017

Given the importance of sugar to humanity, clean cane production has become a source of concern for both academic and producers alike. Focusing on the largest producing and exporting countries of processed and refined sugarcane is the most appropriate means of understanding the concepts evolving around clean cane production. Climate change has not directly reduced the quantity of clean cane produced due to an increase in use of chemical products in farming for sugar cane, but has negatively affected the quality of output. Disease prevalence in harvested cane as well as high soil erosion from global warming have been key elements of the sudden decline in quality cane harvesting and processing. This decline in quality has not only reduce the amount of revenue accruable to farmers but with the consequence of future production prospect if improperly addressed. This study carried out a desk research methodology to review extant literature to identify contemporary issues that needs to be urgently researched on. While a number of issues were uncovered by this study, it was found that scientific experiments and mathematical models enhance theoretical facts on successful and disease free clean cane production methods. But due to the practicability exceptions and the inherent limitations in outcomes of experiments, the research stresses on the importance of field work through observations before theoretical assessments on the findings and the causes of disease prevalence and quality decline in output. This is hoped will sanitize the cane production process and output for the present and future generations.
Usability Evaluation Method for VRLA Battery Measuring Equipment
Authors: Jiang Haifeng , Lin Shusheng
Published: September 2017

This paper presents a method for evaluating the availability of lead-acid battery test equipment and designs the corresponding evaluation mathematical model. International standard IEC60896-2 specifies the lead-acid battery internal resistance level. Because the internal resistance value is usually micro-Ohm level and the lead-acid battery has special electrochemical characteristics, it’s very difficult to measure it. Until now no authority can officially provides the actual resistance value for a given battery. However, the industry has agreed that the internal resistance will gradually increases during the use of the battery and the performance of the battery has close relationship with the change of the internal resistance, so even if the measurement equipment can not measure the absolute actual resistance, but as long as the battery can be measured a small change in internal resistance, it has a high availability. In this paper, we propose a micro-incremental verification method and a mathematical model to facilitate, accurately and quickly verify whether the battery internal resistance test equipment can accurately and stably measure the internal resistance of the battery, and provide technical verification reference for selecting the battery measuring equipment.
Editorial: Religião, Direitos Humanos e Direitos da Natureza
Authors: Oliveira Pedro Assis Ribeiro de
Published: September 2017

Horizonte, Belo Horioznte, v. 15, n. 47, jul./set. 2017

Editorial: Religião, Direitos Humanos e Direitos da Natureza 

 
Teologia, Direitos Humanos e Pensamento Decolonial
Authors: Cunha Carlos Alberto Motta
Published: September 2017

No livro Se Deus fosse um ativista dos direitos humanos, Boaventura de Sousa Santos defende a ideia de que o diálogo entre os direitos humanos e as teologias progressistas é uma boa possibilidade para o desenvolvimento de práticas interculturais e emancipadoras (2014, p.113). Como a teologia pode contribuir para a reconstrução da humanidade dos direitos humanos? A contemporaneidade com toda a sua complexidade reclama a construção de uma teologia consciente da pluralidade cultural e religiosa capaz de abraçar dentro de seu horizonte as experiências sócio-religiosas do conjunto da humanidade. A tarefa de decolonizar a teologia, e/ou de recriar seu conteúdo, não implica apenas uma novidade no objeto, mas exige também uma novidade no sujeito, ou seja, faz-se necessário um novo tipo de teólogo, com um novo tipo de consciência e postura diante da atualidade. Na busca por respostas aproximativas, este artigo faz apontamentos sobre o processo necessário de decolonização da teologia cristã almejando uma intelecção da fé que seja pública e engajada nas causas do mundo e do humano.
Igreja Católica, direitos reprodutivos e direitos ambientais
Authors: Diniz Alves José Eustáquio , Cavenaghi Suzana
Published: September 2017

O objetivo deste texto é apresentar e debater alguns pontos de interseção da esfera dos direitos humanos com o campo da religião, abordando, em especial, os encontros e desencontros referentes às doutrinas da Igreja Católica sobre os direitos reprodutivos e os direitos ambientais. Para tanto, reconstituímos uma narrativa histórica e relacional do debate sobre as origens e a evolução da transição demográfica e dos direitos humanos, desde a época da Revolução Francesa. Por meio de uma análise comparativa e contextualizada, apresentamos o debate sobre população e desenvolvimento sustentável e as visões sobre os direitos reprodutivos e ambientais expostos em Conferências da Organização das Nações Unidas e nas encíclicas Humanae Vitae e Laudato Si’. Argumentamos que desde o final do século XVIII até os dias atuais, o progresso humano se deu às custas do regresso ambiental e, nessa rota divergente, aumenta a tensão entre a dinâmica do crescimento populacional e a efetivação dos direitos reprodutivos e dos direitos ambientais. Desta forma, assinalamos que no Estado democrático de direito, com respeito aos princípios da laicidade, a tolerância religiosa é essencial para o adequado equacionamento da questão dos direitos reprodutivos e para o aprofundamento do debate sobre os direitos ambientais.
Discursos religiosos e sociedade democrática
Authors: Paulo Neto Alberto , Perondi Ildo
Published: September 2017

O artigo investiga a pertinência dos discursos religiosos para a construção da sociedade democrática. A contemporaneidade filosófica tem observado que as religiões podem contribuir para a realização do objetivo de fraternidade e solidariedade entre os cidadãos com distintas orientações axiológicas. A teoria do discurso de Jürgen Habermas analisa que as sociedades contemporâneas estão vivenciando o processo de pós-secularização e o ressurgimento das religiões na esfera pública. O filósofo alemão considera que as instituições religiosas têm o conteúdo normativo e a legitimidade que está ausente nas instituições políticas e nos atores políticos. As religiões mundiais se caracterizam pelas ações sociais e o incentivo à solidariedade aos seus fiéis. No nível pós-metafísico de fundamentação da forma política, os discursos religiosos podem motivar os cidadãos para a atitude comunicativa e o entendimento sobre as normas sociais que deverão reger a sociedade justa e inclusiva. Nesse sentido, a experiência de auto-esclarecimento das religiões sobre as suas doutrinas e princípios de fé poderá colaborar para o entendimento entre os cidadãos religiosos e não-religiosos. Por fim, a análise da experiência católica de autorreflexão sobre suas doutrinas e o relacionamento com as diversas religiões se tornou o exemplo de diálogo para as entidades religiosas no mundo secular.
Leitura bioética de variações sociais da vigilância em condomínios
Authors: Anjos Marcio Fabri dos , Martins Rogerio Jolins
Published: September 2017

O objetivo do artigo é pensar a bioética nas variações sociais da vigilância em condomínios. A vigilância é ambivalente no seu conceito e em suas práticas e serve tanto para proteger quanto para dominar. Este é um estudo conceitual bibliográfico que, inicialmente, descreve a passagem do sentido de cuidar para uma relação de domínio, seguida por algumas experiências de variações socioculturais de vigilância; um terceiro passo aborda as regras da vigilância que garantem a coesão nos condomínios; e, por fim, faz-se uma leitura bioética dos processos de vigiar. A bioética questiona o modelo atual de vigilância que tenta salvaguardar a segurança de um grupo, dentro de uma sociedade composta por violências, mas que não atende toda a coletividade. Por isso, tal modelo se mostra insuficiente para garantir uma segurança efetiva que se busca. Propõe, no entanto, que se busque um ambiente seguro no qual a segurança e a liberdade estejam em equilíbrio.
O discurso profético da Bíblia Hebraica e a ética contemporânea: novas tendências e aproximações
Authors: Sousa Rodrigo Franklin de
Published: September 2017

O presente artigo discute o crescente interesse pelos textos proféticos da Bíblia Hebraica como fontes para uma reflexão ética e religiosa relevante para o contexto contemporâneo. Para descrever esses desenvolvimentos, nosso trabalho parte de uma breve discussão sobre o uso metafórico do conceito de profecia, seguida por um breve panorama da pesquisa contemporânea sobre a ética nos profetas bíblicos. Observamos em particular a proposta da existência de uma concepção análoga ao conceito de “Lei Natural” no livro de Isaías e sua influência sobre novos estudos sobre profecia e ética ambiental. Por fim, oferecemos uma avaliação geral das implicações hermenêuticas dessas novas propostas. O foco do nosso trabalho se concentra principalmente no contexto anglo-saxônico, onde essa abordagem tem tido maior repercussão. A presente análise buscou mostrar que, para além do uso metafórico do conceito de “profecia”, diversos segmentos da academia têm demonstrado maior interesse em integrar o elemento ético dos profetas e o pensamento ético contemporâneo a partir do resgate exegético de temas e conceitos efetivamente oriundos da literatura profética. Esse resgate tem o potencial de fomentar novas linhas de reflexão e ação.
A pneumatologia como fundamento teológico do diálogo inter-religioso para as Assembleias de Deus no Brasil
Authors: Lima Adriano Sousa
Published: September 2017

 As Assembleias de Deus representam o pentecostalismo clássico, que teve início no Brasil, no ano de 1911, tendo como base a experiência do Espírito e de seus dons. Hoje, essas igrejas somam mais de 15 milhões de membros e a doutrina sobre o Espírito Santo continua sendo uma das suas bases mais importantes. O Brasil de hoje, diferente de 1911, é um país pluralizado na sua cultura e na manifestação religiosa. Diante desse contexto, o diálogo entre as religiões é um imperativo fundamental no Brasil. O Espírito Santo, promove a unidade, o diálogo, a convivência e a amizade entre os diferentes. É o Espírito que sopra vida e comunhão em lugares diversos.  Por essa razão, o Espírito pode ser base, para os assembleianos, para um diálogo entre as diferentes religiões. Assim, a pesquisa tem como objetivo fundamentar, em função das Assembleias de Deus, o diálogo inter-religioso a partir da doutrina do Espírito Santo. Para isso, buscará extrair da pneumatologia elementos que contribuam para repensar a teologia pentecostal das assembleias de Deus, a fim de introduzi-las no diálogo inter-religioso. A partir da metodologia de análise bibliográfica, ficarão claras as conclusões seguintes: o Espírito Santo está presente em todo ser humano; o cuidado com o meio ambiente, a busca pela justiça e pela paz, são aspectos pneumatológicos comuns a todos os cristãos e pertinentes a diferentes tradições religiosas. O Espírito promove amizade e comunhão entre os seres humanos; em termos concretos, o resultado é a convivência harmoniosa entre pessoas de diferentes tradições religiosas. Assim, é possível concluir a fecundidade da pneumatologia como fundamento para o diálogo inter-religioso nas Assembleias de Deus.
Turbulent Entrainment Into Volcanic Plumes: New Constraints From Laboratory Experiments on Buoyant Jets Rising in a Stratified Crossflow
Authors: Aubry T. J. , Carazzo G. , Jellinek A. M.
Published: October 2017

Predictions for the heights and downwind trajectories of volcanic plumes using integral models are critical for the assessment of risks and climate impacts of explosive eruptions but are strongly influenced by parameterizations for turbulent entrainment. We compare four popular parameterizations using small scale laboratory experiments spanning the large range of dynamical regimes in which volcanic eruptions occur. We reduce uncertainties on the wind entrainment coefficient β which quantifies the contribution of wind‐driven radial velocity shear to entrainment and is a major source of uncertainty for predicting plume height. We show that models better predict plume trajectories if (i) β is constant or increases with the plume buoyancy to momentum flux ratio and (ii) the superposition of the axial and radial velocity shear contributions to the turbulent entrainment is quadratic rather than linear. Our results have important implications for predicting the heights and likelihood of collapse of volcanic columns.
Dissolved Organic Matter Compositional Change and Biolability During Two Storm Runoff Events in a Small Agricultural Watershed
Authors: Eckard Robert S. , Pellerin Brian A. , Bergamaschi Brian A. , Bachand Philip A. M. , Bachand Sandra M. , Spencer Robert G. M. , Hernes Peter J.
Published: September 2017

Agricultural watersheds are globally pervasive, supporting fundamentally different organic matter source, composition, and concentration profiles in comparison to natural systems. Similar to natural systems, agricultural storm runoff exports large amounts of organic carbon from agricultural land into waterways. But intense management of upper soil layers, waterway channelization, wetland and riparian habitat removal, and postharvest vegetation removal promise to uniquely drive organic matter release to waterways. During a winter first flush and a subsequent storm event, this study investigated the influence of a small agricultural watershed on dissolved organic matter (DOM) source, composition, and biolability. Storm water discharge released strongly terrestrial yet biolabile (23 to 32%) dissolved organic carbon (DOC). Following a 21 day bioassay, a parallel factor analysis identified an 80% reduction in a protein‐like (phenylpropyl) component (C2) that was previously correlated to lignin phenol concentration, and a 10% reduction in a humic‐like, terrestrially sourced component (C4). Storm‐driven releases tripled DOC concentration (from 2.8 to 8.7 mg L−1) during the first flush event in comparison to base flow and were terrestrially sourced, with an eightfold increase in vascular plant derived lignin phenols (23.0 to 185 μg L−1). As inferred from system hydrology, lignin composition, and nitrate as a groundwater tracer, an initial pulse of dilute water from the upstream watershed caused a counterclockwise DOC hysteresis loop. DOC concentrations peaked after 3.5 days, with the delay between peak discharge and peak DOC attributed to storm water hydrology and a period of initial water repellency of agricultural soils, which delayed DOM leaching.
Jun dimerization protein 2 controls hypoxia‐induced replicative senescence via both the p16Ink4a‐pRb and Arf‐p53 pathways
Authors: Nakade Koji , Lin Chang‐Shen , Chen Xiao‐Yu , Tsai Ming‐Ho , Wuputra Kenly , Zhu Zhi‐Wei , Pan Jian‐Zhi , Yokoyama Kazunari K.
Published: September 2017

The main regulators of replicative senescence in mice are p16Ink4a and Arf, inhibitors of cell cycle progression. Jun dimerization protein 2 (JDP2)‐deficient mouse embryonic fibroblasts are resistant to replicative senescence through recruitment of the Polycomb repressive complexes 1 and 2 to the promoter of the gene that encodes p16Ink4a and inhibits the methylation of lysine 27 of the histone H3 locus. However, whether or not JDP2 is able to regulate the chromatin signaling of either p16Ink4a‐pRb or Arf‐p53, or both, in response to oxidative stress remains elusive. Thus, this study sought to clarify this point. We demonstrated that the introduction of JDP2 leads to upregulation of p16Ink4a and Arf and decreases cell proliferation in the presence of environmental (20% O2), but not in low (3% O2) oxygen. JDP2‐mediated growth suppression was inhibited by the downregulation of both p16Ink4a and Arf. Conversely, the forced expression of p16Ink4a or Arf inhibited cell growth even in the absence of JDP2. The downregulation of both the p53 and pRb pathways, but not each individually, was sufficient to block JDP2‐dependent growth inhibition. These data suggest that JDP2 induces p16Ink4a and Arf by mediating signals from oxidative stress, resulting in cell cycle arrest via both the p16Ink4a‐pRb and Arf‐p53 pathways.
Ruthenium‐Catalyzed para‐Selective C−H Alkylation of Aniline Derivatives
Authors: Leitch Jamie A. , McMullin Claire L. , Paterson Andrew J. , Mahon Mary F. , Bhonoah Yunas , Frost Christopher G.
Published: October 2017

The para‐selective C−H alkylation of aniline derivatives furnished with a pyrimidine auxiliary is herein reported. This reaction is proposed to take place via an N−H‐activated cyclometalate formed in situ. Experimental and DFT mechanistic studies elucidate a dual role of the ruthenium catalyst. Here the ruthenium catalyst can undergo cyclometalation by N−H metalation (as opposed to C−H metalation in meta‐selective processes) and form a redox active ruthenium species, to enable site‐selective radical addition at the para position.
Oxetane Grafts Installed Site‐Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo
Authors: Martínez‐Sáez Nuria , Sun Shuang , Oldrini Davide , Sormanni Pietro , Boutureira Omar , Carboni Filippo , Compañón Ismael , Deery Michael J. , Vendruscolo Michele , Corzana Francisco , Adamo Roberto , Bernardes Gonçalo J. L.
Published: October 2017

A four‐membered oxygen ring (oxetane) can be readily grafted into native peptides and proteins through site‐selective bis‐alkylation of cysteine residues present as disulfides under mild and biocompatible conditions. The selective installation of the oxetane graft enhances stability and activity, as demonstrated for a range of biologically relevant cyclic peptides, including somatostatin, proteins, and antibodies, such as a Fab arm of the antibody Herceptin and a designed antibody DesAb‐Aβ against the human Amyloid‐β peptide. Oxetane grafting of the genetically detoxified diphtheria toxin CRM197 improves significantly the immunogenicity of this protein in mice, which illustrates the general utility of this strategy to modulate the stability and biological activity of therapeutic proteins containing disulfides in their structures.
Guest‐Switchable Multi‐Step Spin Transitions in an Amine‐Functionalized Metal–Organic Framework
Authors: Liu Wei , Peng Yuan‐Yuan , Wu Si‐Guo , Chen Yan‐Cong , Hoque Md. Najbul , Ni Zhao‐Ping , Chen Xiao‐Ming , Tong Ming‐Liang
Published: October 2017

Materials with hysteretic multi‐step spin‐crossover (SCO) have potential application in high‐order data storage. Here, an unprecedented hysteretic four‐step SCO behavior with the sequence of LS↔HS0.25LS0.75↔HS0.5LS0.5↔ HS0.75LS0.25↔HS is found in a three‐dimensional (3D) Hofmann‐type metal–organic framework (MOF), which is evidenced by magnetic, differential scanning calorimetry, and crystal data. Further experiments involving guest exchange leads to the first reversible modulation of four‐, two‐, and one‐stepped SCO behaviors, which provides a new strategy for developing multi‐step SCO materials.
Tetrazole‐Based Probes for Integrated Phenotypic Screening, Affinity‐Based Proteome Profiling, and Sensitive Detection of a Cancer Biomarker
Authors: Cheng Ke , Lee Jun‐Seok , Hao Piliang , Yao Shao Q. , Ding Ke , Li Zhengqiu
Published: October 2017

Target‐identification phenotypic screening has been a powerful approach in drug discovery; however, it is hindered by difficulties in identifying the underlying cellular targets. To address this challenge, we have combined phenotypic screening of a fully functionalized small‐molecule library with competitive affinity‐based proteome profiling to map and functionally characterize the targets of screening hits. Using this approach, we identified ANXA2, PDIA3/4, FLAD1, and NOS2 as primary cellular targets of two bioactive molecules that inhibit cancer cell proliferation. We further demonstrated that a panel of probes can label and/or image annexin A2 (a cancer biomarker) from different cancer cell lines, thus providing opportunities for potential cancer diagnosis and therapy.
Sprout‐like Growth of Mesoporous Mo2C/NC Nanonetworks as Efficient Electrocatalysts for Hydrogen Evolution
Authors: Fan Meihong , Zheng Yuenan , Li Ang , Ma Yali , Huo Qisheng , Qiao Zhen‐An , Dai Sheng
Published: October 2017

Owing to their high surface areas, porous networks, nanosized walls, and unique electronic structure, mesoporous metal carbides with tailored nanoarchitectures are of particular interest for their prominent potential applications in various fields, including energy storage, fuel cells, and catalysis. Herein, we report a sprout‐like growth strategy for the preparation of a mesoporous β‐Mo2C nanonetwork embedded in a nitrogen‐rich carbon matrix. The nanoarchitecture can be tailored from a mesoporous Mo2C nanonetwork film into Mo2C nanoparticles embedded into the carbon layer. The as‐prepared β‐Mo2C material was demonstrated to drive a current density of 10 mA cm−2 at a low overpotential of 140 mV for the hydrogen evolution reaction (HER) in acidic conditions and to remain stable for at least 120 h. The excellent electrocatalytic performance may be from (1) mesoporous Mo2C frameworks offering numerous accessible active sites; (2) a carbon layer that protects the Mo2C from accumulation and favors electron transportation; and (3) shortened diffusion paths and ultrafine crystallinity that benefit its catalytic performance.
Statistical inference using generalized linear mixed models under informative cluster sampling
Authors: Kim Jae Kwang , Park Seunghwan , Lee Youngjo
Published: September 2017

When a sample is obtained from a two‐stage cluster sampling scheme with unequal selection probabilities the sample distribution can differ from that of the population and the sampling design can be informative. In this case making valid inference under generalized linear mixed models can be quite challenging. We propose a novel approach for parameter estimation using an EM algorithm based on the approximate predictive distribution of the random effect. In the approximate predictive distribution instead of using the intractable sample likelihood function we use a normal approximation of the sampling distribution of the profile pseudo maximum likelihood estimator of the random effects in the level‐one model. Two limited simulation studies show that the proposed method using the normal approximation performs well for modest cluster sizes. The proposed method is applied to the real data arising from 2011 Private Education Expenditures Survey (PEES) in Korea. The Canadian Journal of Statistics 45: 479–497; 2017 © 2017 Statistical Society of Canada
Sugar‐Coated Nanobullet: Growth Inhibition of Cancer Cells Induced by Metformin‐Loaded Glyconanoparticles
Authors: Qian Ruo‐Can , Lv Jian , Li Hao‐Wen , Long Yi‐Tao
Published: October 2017

Metformin, a widely used drug for treating type‐2 diabetes, has now been discovered to reduce cancer cell proliferation. However, further efforts are needed to design effective metformin delivery vehicles, instead of bare metformin. Herein we report a highly efficient transport nanostructure based on core–shell glyconanoparticles (GNPs), with gold as the core and dextran as the shell interspersed with metformin molecules. The dextran shell facilitates the entry of GNPs into living cells, which allows the subsequent release of metformin. Using MCF‐7 breast cancer cells as an example, significant cell growth inhibition was observed after treatment of metformin‐containing GNPs (MGNPs). Compared with bare metformin or bare GNPs, MGNPs show a stronger capacity for cell growth inhibition with good biocompatibility. Furthermore, inactivation of mitochondria and activation of p53 protein are observed during MGNP treatment, which provides evidence for metformin‐induced cell apoptosis pathways. This work provides a new therapeutic tool for the treatment of cancer.
A Ferrocene–Tryptophan Conjugate: The Role of the Indolic Nitrogen in Supramolecular Assembly
Authors: Falcone Natashya , Basak Shibaji , Dong Bin , Syed Jebriel , Ferranco Annaleizle , Lough Alan , She Zhe , Kraatz Heinz‐Bernhard
Published: October 2017

Bio‐organometallic ferrocene‐containing amino acids and peptides have been reported to form gels and are interesting to study due to their structural properties and applications for biological purposes. In this study, a ferrocene‐dicarboxylic acid derivative of the dipeptide tryptophan–tryptophan was investigated. The indolic nitrogen in the amino acid tryptophan is important for biological functions due to its role in hydrogen bonding. Here, intermolecular interactions with the indolic nitrogen allow this conjugate to self‐assemble into a fibrous supramolecular structure that forms a stable gel. Rheological analysis demonstrates the self‐healing nature of this gel. Interestingly, X‐ray analysis of this ferrocene–peptide conjugate reveals close contacts involving tryptophan, in particular the indole NH group in interactions with an adjacent neighboring molecule.