bluuebunny/crossref_metadata_2025 huggingface dataset:
Cross‐linguistic study of lateral misarticulation using electropalatography
Authors: Suzuki N. , Wakumoto M. , Michi K. , Dent H. , Gibbon F. , Hardcastle W. J.
Published: November 2007

ABSTRACTS

This paper reports on some preliminary aspects of a collaborative cross‐linguistic study of normal and disordered Japanese and British English speech. The investigation compares lateralised productions of /s/ which are abnormal in the two languages. EPG and acoustic recordings were made of four Japanese and four British subjects. The EPG patterns were classified according to certain criteria, such as the presence or absence of complete constriction between the tongue and the hard palate, and the area and location of this contact. Findings revealed that lateralised articulations varied between individual speakers, but that Japanese and English productions were broadly similar. Acoustically, misarticulations in both languages were characterised by a lower frequency of peak energy than would be expected in normal productions.

L'article rend compte de certains aspects préliminaires d'une collaboration en vue d'une étude comparée des élocutions normale et perturbée en anglais de Grande‐Bretagne et en japonais. La recherche compare les productions latéralisées de /s/ qui sont anormales dans les deux langues. L'on a procédé à des enregistrements électropalatographiques et acoustiques de quatre sujets japonais et quatre britanniques. Les modèles électropalatographiques onr été classés selon des critères tels que la présence ou l'absence de constriction entre la langue et le palais dur, et selon la surface et le lieu de ce contact. Les résultats montrent que les articulations latéralisées ont varié selon les individus, mais que les réalisations japonaises et britanniques étaient en gros semblables. Du point de vue acoustique, les erreurs d'articulation dans les deux langues se caractérisaient par un abaissement de la fréquence de l'énergie maximum par rapport à ce qu'on aurait attendu dans des réalisations normales.

Dieser Beitrag berichtet von den ersten Ergebnissen einer kollaborativen intersprachlichen Untersuchung von Sprechstörungen im Japanischen und Englischen. Lateralisierte /s/‐Produktionen, die in beiden Sprachen als abnormal gelten, werden verglichen. Es wurden akustische Aufnahmen und EPG‐Aufzeichnungen von vier japanischen und vier britischen Sprechern gemacht. Die EPG‐Muster wurden nach Kriterien wie das Vorhandensein oder Fehlen eines vollständigen Verschlusses zwischen Zunge und Gaumen sowie Position des Kontakts klassifiert. Es zeigte sich, da***β die lateralisierten Artikulationen von Sprecher zu Sprecher variierten, da***β aber japanische und britische Produktionen insgesamt vergleichbar waren. Akustisch hatten die Fehlartikulationen in beiden Sprachen einen tieferfrequentigen Energiegipfel, als dies bei normaler Produktion zu erwarten wäre.

ABSTRACTS
Cover Picture: In‐Situ Synchrotron X‐Ray Microtomography Studies of Microstructure and Damage Evolution in Engineering Materials (Adv. Eng. Mater. 11/2007)
Authors: Beckmann F. , Grupp R. , Haibel A. , Huppmann M. , Nöthe M. , Pyzalla A. , Reimers W. , Schreyer A. , Zettler R.
Published: November 2007

The cover shows the study of the bulk material flow within the stir zone of friction stir welded auminium alloys with implated Cu and Ti powders. By applying synchrotron radiation based microtomography the simultaneous marker material displacement (Cu and Ti) can be visualized non‐invasively in 3D. More about the usage of in‐situ synchrotron x‐ray microtomography to study microstructure and damage evolution in engineering materials can be read in the review article by A. Pyzalla et al. on page 939.

In materials science X‐ray microtomography has evolved as an increasingly utilized technique for characterizing the 3D microstructure of materials. The fundamentals of X‐ray microtomography experimental methods and the reconstruction and data evaluation processes are briefly described. A review of in‐situ synchrotron X‐ray microtomography studies in literature is given. Examples of recent work include in‐situ microtomography investiagtions of metallic foams, in‐situ studies of the sintering of copper particles, and in‐situ investigations of creep damage evolution in composites. Future perspectives of in‐situ X‐ray microtomography studies in materials science are outlined.
3‐D Integrated All‐Solid‐State Rechargeable Batteries
Authors: Notten P. H. L. , Roozeboom F. , Niessen R. A. H. , Baggetto L.
Published: November 2007

Portable society urgently calls for integrated energy supplies. This holds for autonomous devices but even more so for future medical implants. Evidently, rechargeable integrated all‐solid‐state batteries will play a key role in these fields, enabling miniaturization, preventing electrode degradation upon cycling and electrolyte leakage. Planar solid‐state thin film batteries are rapidly emerging but reveal several potential drawbacks, such as a relatively low energy density and the use of highly reactive lithium. Thin film Si‐intercalation electrodes covered with a solid‐state electrolyte are found to combine a high storage capacity of 3500 mAh g–1 with high cycle life, enabling to integrate batteries in Si. Based on the excellent intercalation chemistry of Si, a new 3D‐integrated all‐solid‐state battery concept is proposed. High aspect ratio cavities and features, etched in silicon, will yield large surface area batteries with anticipated energy density of about 5 mWh μm–1 cm–2, i.e. more than 3 orders of magnitude higher than that of integrated capacitors.
A New Solid‐Phase Reaction System Utilizing a Temperature‐ Responsive Catalyst: Oxidative Cyclization with Hydrogen Peroxide
Authors: Hamamoto Hiromi , Suzuki Yachiyo , Takahashi Hideyo , Ikegami Shiro
Published: November 2007

A switchable catalyst based on temperature change provides a novel solid‐phase reaction system in water. An increase in catalyst affinity for organic substrates at higher temperature led to efficient activity driving the solid inner‐phase reaction, and loss of affinity at lower temperature allowed easy separation of organic products upon completion of the reaction. Application of this catalyst intelligence to design a novel catalytic system brought about an efficient oxidative cyclization with hydrogen peroxide, a useful method of accessing oxygen heterocycles.
Practical Two‐Step Synthesis of an Enantiopure Aliphatic Terminal (S)‐Epoxide Based on Reduction of Haloalkanones with “Designer Cells”
Authors: Berkessel Albrecht , Rollmann Claudia , Chamouleau Francoise , Labs Stefanie , May Oliver , Gröger Harald
Published: November 2007

A practical biocatalytic method for the synthesis of aliphatic β‐halogenated (S)‐alcohols as epoxide precursors by means of an enantioselective reduction of the corresponding ketones with recombinant whole cells, bearing an alcohol dehydrogenase and a glucose dehydrogenase, was developed. The biotransformations operate at high substrate concentrations of up to 208 g/L, and afford the (S)‐β‐halohydrins with both high conversions of >95 % and enantioselectivities of >99 % ee. Base‐induced cyclization of the β‐halohydrin intermediates gave the desired (S)‐epoxides in high yield and enantiomeric purity (>99 % ee).
Memory Effects in Palladium‐Catalyzed Allylic Alkylations of 2‐Cyclohexen‐1‐yl Acetate
Authors: Svensen Nina , Fristrup Peter , Tanner David , Norrby Per‐Ola
Published: November 2007

The objective of this work was to characterize the enantiospecificity of the allylic alkylation of enantioenriched 2‐cyclohexen‐1‐yl acetate with the enolate ion of dimethyl malonate catalyzed by unsymmetrical palladium catalysts. The precatalysts employed were (η3‐allyl)PdLCl, where L is a monophosphine ligand [PPh3, PCy3, P(2‐BiPh)Cy2, or P(t‐Bu)3], all of which afforded enantiospecificity to some extent (5–47 %). Quantum mechanical calculations show that, theoretically, the enantiospecificity should be high due to a preference for the “trans to P” transition state in both formation of the η3‐allyl intermediate and nucleophilic attack. However, the observed enantiospecificity is relatively low due to isomerization of the η3‐allyl intermediate and/or dynamic equilibria between the catalytically active (η3‐allyl)PdLCl species and [(η3‐allyl)PdL2]+ or [(η3‐allyl)PdCl]2. It was also observed experimentally that increasing the bulk of the phosphine inhibits formation of the [(η3‐allyl)PdL2]+ complexes, significantly increasing the observed enantiospecificity for some of the ligands.
Ligand‐Free Copper‐Catalyzed N‐Arylation of Nitrogen Nucleophiles
Authors: Correa Arkaitz , Bolm Carsten
Published: November 2007

Versatile, simple and inexpensive ligand‐free, copper‐catalyzed N‐arylations of sulfoximines and nitrogen‐containing heterocycles have been developed affording N‐arylated products in high yields.
Simultaneous batching and scheduling of single stage batch plants with parallel units
Authors: Castro Pedro M. , Erdirik‐Dogan Muge , Grossmann Ignacio E.
Published: November 2007

This article deals with the optimal short‐term scheduling of single stage batch plants with sequence‐dependent changeovers together with the optimal selection of the number of batches to produce. The novelty of the article is that instead of following the traditional approach of considering one processing task per batch, all batches of the product are now aggregated into a single task. Integer variables that hold the number of batches to produce are used to characterize these aggregated tasks. Two conceptually different continuous‐time models are proposed. They rely on either multiple time grids or global precedence sequencing variables for event representation and generate a mixed integer linear program. The new formulations are compared to a traditional resource‐task network multiple time grid approach as well as to a recent bounding model with immediate precedence sequencing variables. The results for several example problems show the new multiple time grid formulation as the best overall performer. When compared to the traditional approach, one order of magnitude savings in computational effort are achieved due to the need of fewer event points to get to the global optimal solutions. © 2007 American Institute of Chemical Engineers AIChE J, 2008
Work‐related asthma in the Educational Services industry: California, Massachusetts, Michigan, and New Jersey, 1993–2000
Authors: Mazurek Jacek M. , Filios Margaret , Willis Ruth , Rosenman Kenneth D. , Reilly Mary Jo , McGreevy Katharine , Schill Donald P. , Valiante David , Pechter Elise , Davis Letitia , Flattery Jennifer , Harrison Robert
Published: November 2007

Objectives

To characterize work‐related asthma (WRA) cases working in the educational services industry identified by state‐based occupational disease surveillance systems.

Methods

We examined 2,995 WRA cases reported from 1993 to 2000 to four states: California, Massachusetts, Michigan, and New Jersey.

Results

A total of 265 (9%) WRA cases were employed in the educational services industry; 69% of cases were classified as new‐onset asthma and 31% as work‐aggravated asthma. New‐onset asthma cases were further classified as occupational asthma (61%) or as reactive airways dysfunction syndrome (8%). The most frequently reported occupation was teachers and teachers' aides (54%). The most frequently reported agents were indoor air pollutants (28%), unspecified mold (16%), dusts (14%), and cleaning products (7%).

Conclusions

Asthma within the educational services industry is an occupational health problem. The health of school employees should also be considered when initiatives addressing asthma among schoolchildren are instituted. The identification, elimination, and/or control of respiratory hazards are important factors for the protection of staff and students alike. Am. J. Ind. Med. 51:47–59, 2008. © 2007 Wiley‐Liss, Inc.
Dupuytren's disease: Personal factors and occupational exposure
Authors: Lucas Gérard , Brichet Anne , Roquelaure Yves , Leclerc Annette , Descatha Alexis
Published: November 2007

Background

The etiology of Dupuytren's disease is unknown, and the role of occupational exposure is still debated. Our objective was to study the association between occupational exposures, personal risk factors and Dupuytren's disease.

Methods

In this cross‐sectional survey, nine occupational physicians performed clinical examinations, focused on Dupuytren's disease, of 2,406 French male civil servants employed at the Equipment Ministry in 1998 and interviewed them about medical history, leisure manual exposure and occupational biomechanical exposure to vibrations and manual work. A cumulative occupational exposure score was defined, with three levels of exposure.

Results

Dupuytren's disease was diagnosed in 212 men (8.8%). The occupational exposure score was significantly higher in this group of cases than in the rest of the sample (377 (SD280) vs. 223 (SD250), respectively; P < 0.0001). Occupational exposure was associated with Dupuytren's disease (adjusted Odds Ratio = 2.20 [1.39–3.45] for the intermediate and 3.10 [1.99–4.84] for the high exposure groups), with adjustment for age, leisure physical activities, alcohol consumption (≥5 servings per day), history of diabetes, epilepsy, hand trauma, and familial history of Dupuytren's disease.

Conclusion

Manual work exposure was associated with Dupuytren's disease after adjustment for personal risk factors. Longitudinal studies are needed to confirm these results. Am. J. Ind. Med. 51:9–15, 2008. © 2007 Wiley‐Liss, Inc.
Investigation on the development of sturdy bioactive hydrogel beads
Authors: Sangeetha K. , Emilia Abraham T.
Published: November 2007

Biocatalytic hydrogel beads, which retain higher activity, expand, and contract with changes in pH, having biocompatibility, are developed. Composite spherical beads of chitosan having a diameter of 1–2 mm were prepared by ionic gelation using sodium tripolyphosphate (TPP). Above 3% TPP, the activity of the enzyme decreases. The mechanical strength of the chitosan–TPP beads was further improved by the addition of clay or cassava starch granules. The immobilization of protease (fungal, Aspergillus) was done with glutaraldehyde crosslinking. The chitosan–starch hydrogel beads showed significant increase in firmness and stiffness when compared with chitosan–clay beads. The swelling studies show that the particles expand at pH 1.2 and contract at pH 7.4. The activity retention of the immobilized protease was as high as 70% and exhibited a high pH and lower temperature optima than the free enzyme. Chitosan–starch hydrogel beads exhibited degradation peaks at about 90–110°C in TGA analysis. The biocatalyst beads retained 85% of the original catalytic activity even after eight cycles of repeat use. The freeze‐dried beads has good storage stability and can be used either as artificial bioreactor systems in detergent or in therapeutic formulations © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2008
iso‐OPDA: An Early Precursor of cis‐Jasmone in Plants?
Authors: Dąbrowska Paulina , Boland Wilhelm
Published: November 2007

cis‐Jasmone is a highly appreciated fragrance and plant‐derived signal molecule that controls pollination, attracts parasitoids of attacking herbivores, and serves as an intra‐ and interspecific signal that controls gene expression. cis‐Jasmone is produced from linolenic acid along the jasmonic acid cascade. In addition to the conversion of jasmonic acid into cis‐jasmone, a novel pathway might exist that converts cis‐oxophytodienoic acid (OPDA), an early precursor of jasmonic acid, into iso‐OPDA. The planar iso‐OPDA is degraded by β‐oxidation to 3,7‐didehydrojasmonic acid, which yields cis‐jasmone by spontaneous decarboxylation. The degradation of iso‐OPDA to cis‐jasmone is demonstrated for many plant species and the yeast Saccharomyces cerevisiae.
How Can Rotaxanes Be Modified by Varying Functional Groups at the Axle?—A Combined Theoretical and Experimental Analysis of Thermochemistry and Electronic Effects
Authors: Spickermann Christian , Felder Thorsten , Schalley Christoph A. , Kirchner Barbara
Published: November 2007

We present theoretically as well as experimentally determined thermochemical data of the non‐covalent interactions in different axle‐substituted pseudorotaxanes. The overall interaction energy lies in the region of 35 kJ mol−1, independent of the substitution pattern at the axle. Because rearrangement energies of 7 and 3 kJ mol−1 are required for wheel and axle, respectively, the sum of the net interactions of individual non‐covalent bonds must exceed 10 kJ mol−1 to achieve a successful host–guest interaction. The geometrical analysis shows three hydrogen bonds, and the close inspection of the individual dipole moments as well as the individual hydrogen bonds reveals trends according to the different functional groups at the axle. The individual trends for the different hydrogen bonds almost lead to a cancellation of the substitution effects. From solvent‐effect considerations it can be predicted that the pseudorotaxane is stable in CHCl3 and CH2Cl2, whereas it would dethread in water. Comparing experimentally and theoretically calculated Gibbs free enthalpies, we find reasonable agreement if an exchange reaction of one solvent molecule instead of the direct formation reaction is considered.
Fused Tricyclic Phosphiranes—Analysis of Phosphorus Chemical Shieldings
Authors: Couzijn Erik P. A. , Ehlers Andreas W. , Slootweg J. Chris , Schakel Marius , Krill Steffen , Lutz Martin , Spek Anthony L. , Lammertsma Koop
Published: November 2007

1,2‐Addition of transient W(CO)5‐complexed phosphinidenesexoto hexamethyl Dewar benzene affords the novel 3‐phosphatricyclo[3.2.0.02,4]hept‐6‐ene complexes. The fused tricyclic phosphiranes are obtained as both theZand the thermally less stableEisomers, the31P NMR chemical shifts of which differ by about 60 ppm. A computational investigation shows that the phosphorus pyramidalization and the presence of the γ double bond are responsible for this effect. The semiquantitative results contribute to a more systematic understanding of the structural influences on31P chemical shieldings. The congested double bond of theZisomer can be epoxidized withm‐chloroperbenzoic acid (MCPBA) to afford a fused tetracyclic P,O bis‐adduct.
New Carbon Materials: Biological Applications of Functionalized Nanodiamond Materials
Authors: Krueger Anke
Published: November 2007

Nanoscale diamond particles have become an interesting material. Due to their inertness, small size and surface structure, they are well‐suited for biological applications, such as labelling and drug delivery. Here we discuss the surface structure and functionalisation of diamond nanoparticles. Non‐covalent as well as covalent grafting of bioactive moieties is possible, and first applications of fluorescent diamond nanoparticles are described.
Enantio‐ and Diastereoselective Synthesis of Duocarmycine‐Based Prodrugs for a Selective Treatment of Cancer by Epoxide Opening
Authors: Tietze Lutz F. , Schuster Heiko J. , Hampel Sonja M. , Rühl Stephan , Pfoh Roland
Published: November 2007

For the enantio‐ und diastereoselective synthesis of the prodrug 2, the N‐tert‐butyloxycarbonyl‐protected amine 7 was alkylated with the enantiopure epoxide 14 to give the amide 10. A regio‐ and facial‐selective metal‐mediated cyclisation by using a cuprate led to 17 with an inversion of configuration at C10. Subsequent transformation of the hydroxy group in 17 by using the Appel procedure afforded (1S,10R)‐9 with an unusual double inversion owing to neighbouring‐group participation of the N‐tert‐butoxycarbonyl group. (1S,10R)‐9 is the key intermediate in the synthesis of the prodrug 2, which has been developed for a selective treatment of cancer based on the antibody‐directed enzyme prodrug therapy as an analogue of the natural antibiotic duocarmycine SA (1).
Surfactant‐Free Synthesis of Hyperbranched Monoclinic Bismuth Vanadate and its Applications in Photocatalysis, Gas Sensing, and Lithium‐Ion Batteries
Authors: Zhao Yu , Xie Yi , Zhu Xi , Yan Si , Wang Sunxi
Published: November 2007

Hyperbranched monoclinic BiVO4 (h‐BiVO4) has been synthesized on a large scale and with good uniformity by a surfactant‐free hydrothermal route. h‐BiVO4 consists of four trunks with branches distributed on opposite sides. From observation of the intermediates at an early stage of the reaction process, it can be seen that during formation h‐BiVO4 has different growth rates along the a, b, and c axes. Based on crystal structure analysis and experimental results, h‐BiVO4 shows preferential growth along the [100] direction, and subsequently, along the [010] and [001] directions. As‐synthesized h‐BiVO4 exhibits excellent photocatalytic ability in the photodegradation reaction of an aqueous solution of RB under visible light. Electrochemical measurements predict that h‐BiVO4 possesses high sensitivity to formaldehyde and ethanol gases, favorable discharge capacity, and capacity retention, which indicate potential applications in the fields of sensing devices and lithium‐ion batteries.
A Double Regio‐ and Stereoselective Glycosylation Strategy for the Synthesis of N‐Glycans
Authors: Unverzagt Carlo , Eller Steffen , Mezzato Stefano , Schuberth Ralf
Published: November 2007

A building block approach for biantennary N‐linked oligosaccharides from glycoproteins (N‐glycans) has been developed. Starting from a core trisaccharide (β‐mannosyl chitobiose) containing a benzylidene‐protected β‐mannoside, the attachment of the disaccharide building blocks for the antennae can be performed in a double regio‐ and stereoselective manner. A short synthesis of a GlcNPhtβ1,2Man donor was developed. The benzylidene acetal moiety, as a minimal protection of the β‐mannoside, allows selective α‐glycosylation at OH‐3 of the 2,3‐diol with GlcNβ1,2Man trichloroacetimidate donors. Subsequent debenzylidenation leads to a 4,6‐diol, which can be selectively extended at OH‐6. Overreaction at OH‐4 was generally low when phthalimido‐protected donors were used. This general strategy represents a modular synthesis of N‐glycans and their glycoconjugates.
Polyoxometalates with Internal Cavities: Redox Activity, Basicity, and Cation Encapsulation in [Mn+P5W30O110](15‐n)‐ Preyssler Complexes, with M: Na+, Ca2+, Y3+, La3+, Ce3+, and Th4+.
Authors: Fernandez Jorge A. , Lopez Xavier , Bo Carles , de Graaf Coen , Baerends Evert J. , Poblet Josep M.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Pressure‐Induced Phase Transitions in LiNH2.
Authors: Chellappa Raja S. , Chandra Dhanesh , Somayazulu Maddury , Gramsch Stephen A. , Hemley Russell J.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Crystal Structure and Phonon Properties of Noncentrosymmetric LiNaB4O7.
Authors: Maczka M. , Waskowska A. , Majchrowski A. , Zmija J. , Hanuza J. , Peterson G. A. , Keszler D. A.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Mesoporous Graphitic Carbon Nitride as a Versatile, Metal‐Free Catalyst for the Cyclization of Functional Nitriles and Alkynes.
Authors: Goettmann Frederic , Fischer Anna , Antonietti Markus , Thomas Arne
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Radical‐Mediated Cyclization Reactions Leading to Spiro and [6,6]‐Fused Heterocycles.
Authors: Majumdar K. C. , Debnath P. , Pal A. K. , Chattopadhyay S. K. , Biswas A.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Stereospecific Cyclopropanation of Highly Substituted C—C Double Bonds Promoted by CrCl2. Stereoselective Synthesis of Cyclopropanecarboxamides and Cyclopropyl Ketones.
Authors: Concellon Jose M. , Rodriguez‐Solla Humberto , Mejica Carmen , Blanco Elena G.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chemoselective Synthesis of 1,1‐Diacetates from Aldehydes in the Presence of Al(HSO4)3 under Mild Solvent‐Free Conditions.
Authors: Mirjalili B. F. , Zolfigol M. A. , Bamoniri A. , Amrollahi M. A. , Sheikhan N.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rhenium‐Catalyzed Synthesis of Naphthalene Derivatives via Insertion of Aldehydes into a C—H Bond.
Authors: Kuninobu Yoichiro , Nishina Yuta , Takai Kazuhiko
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rapid Organocatalytic Aldehyde—Aldehyde Condensation Reactions.
Authors: Erkkilae Anniina , Pihko Petri M.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Catalytic Nucleophilic Activation of Acetonitrile via a Cooperative Catalysis of Cationic Ru Complex, DBU, and NaPF6.
Authors: Kumagai Naoya , Matsunaga Shigeki , Shibasaki Masakatsu
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Eco‐Friendly Oxyiodination of Aromatic Compounds Using Ammonium Iodide and Hydrogen Peroxide.
Authors: Narender N. , Reddy K. Suresh Kumar , Mohan K. V. V. Krishna , Kulkarni S. J.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Aerobic Oxidation of Alcohol in Aqueous Solution Catalyzed by Gold.
Authors: Li Huanrong , Guan Bingtao , Wang Wenjin , Xing Dong , Fang Zhao , Wan Xiaobing , Yang Liping , Shi Zhangjie
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Novel Palladium(0)‐Catalyzed Addition of Diphenyl Disulfide to Allenes Leading to Vicinal Disulfides and Its Application to Carbonylation with Carbon Monoxide.
Authors: Kodama Shintaro , Nishinaka Etsuyo , Nomoto Akihiro , Sonoda Motohiro , Ogawa Akiya
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rhodium(II)‐Catalyzed Intramolecular Reactions of Methyl 4‐Diazo‐5‐oxo‐3‐trifluoromethylalk‐2‐enoates in the Presence of 2,5‐Dimethylfuran.
Authors: Zakharova V. M. , Nikolaev V. A.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Spectral Properties of Unsymmetrical Benzoporphyrins Containing Phenoxy Groups or Quinoxaline Fragments.
Authors: Galanin N. E. , Shaposhnikov G. P.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Solvent‐Free Protocol for Facile Condensation of Indoles with Carbonyl Compounds Using Silica Chloride as a New, Highly Efficient, and Mild Catalyst.
Authors: Hasaninejad Alireza , Zare Abdolkarim , Sharghi Hashem , Shekouhy Mohsen , Khalifeh Reza , Beni Alireza Salimi , Zare Ahmad Reza Moosavi
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reductive Heterocyclizations via Indium—Iodine‐Promoted Conversion of 2‐Nitroaryl Imines or 2‐Nitroarenes to 2,3‐Diaryl‐substituted Indazoles.
Authors: Ahn Gil Hwan , Lee Jung June , Jun Young Moo , Lee Byung Min , Kim Byeong Hyo
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Some New 1‐(6‐Fluorobenzothiazol‐2‐yl)‐3‐(4‐fluorophenyl)‐5‐arylpyrazolines and Their Iodine(III) Mediated Oxidation to Corresponding Pyrazoles.
Authors: Aggarwal Ranjana , Kumar Vinod , Singh Shiv P.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Manganese‐Catalyzed Insertion of Aldehydes into a C—H Bond.
Authors: Kuninobu Yoichiro , Nishina Yuta , Takeuchi Takahiro , Takai Kazuhiko
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Asymmetric Lewis Acid Catalyzed Addition of Isocyanides to Aldehydes — Synthesis of 5‐Amino‐2‐(1‐hydroxyalkyl)oxazoles.
Authors: Wang Shixin , Wang Mei‐Xiang , Wang De‐Xian , Zhu Jieping
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
One‐Pot Synthesis of Furocoumarins Through Cascade Addition—Cyclization—Oxidation.
Authors: Cheng Gang , Hu Youhong
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Antimicrobial Evaluation of Some New 3‐Alkyl‐, 3‐(2′‐Naphthyl)isocoumarins and Their (dl)‐3,4‐Dihydroderivatives.
Authors: Khan Zulfiqar Ali , Rama Nasim Hasan , Hussain Muhammad Tahir , Khan Gul Shahzada
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chiral Amine Thiourea‐Promoted Enantioselective Domino Michael‐Aldol Reactions Between 2‐Mercaptobenzaldehydes and Maleimides.
Authors: Zu Liansuo , Xie Hexin , Li Hao , Wang Jian , Jiang Wei , Wang Wei
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reaction of 2‐Chloro‐6‐hydroxy‐5,5‐dimethyl‐5,6‐dihydro‐1H‐pyridine‐3,4,4‐tricarboni triles with Methanol
Authors: Eremkin A. V. , Ershov O. V. , Mol'kov S. N. , Kayukov Ya. S. , Nasakin O. E. , Tafeenko V. A.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Diverse Functionalization of Thiazolo Ring‐Fused 2‐Pyridones.
Authors: Chorell Erik , Das Pralay , Almqvist Fredrik
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A General Modular Method of Azaindole and Thienopyrrole Synthesis via Pd‐Catalyzed Tandem Couplings of gem‐Dichloroolefins.
Authors: Fang Yuan‐Qing , Yuen Josephine , Lautens Mark
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Selectivity Enhancement of Silica‐Supported Sulfonic Acid Catalysts in Water by Coating of Ionic Liquid.
Authors: Gu Yanlong , Karam Ayman , Jerome Francois , Barrault Joel
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cyclopropyl Building Blocks in Organic Synthesis. Part 143. A Two‐Step, Three‐Component Queuing Cascade Leading to Dihydrobenzoxepine and Dihydrobenzazepine Derivatives.
Authors: Yucel Baris , Valentic Natasa , Noltemeyer Mathias , de Meijere Armin
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Triethylborane: An “Old” Reagent with New Functions. 1,2‐Hydroboration.
Authors: Wrackmeyer Bernd , Khan Ezzat , Bayer Stefan , Shahid Khadija
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Zinc‐Mediated Cleavage of Diselenides: A Novel Synthesis of Selenoformates in Aqueous Media.
Authors: Movassagh Barahman , Fazeli Azadeh
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Constituents of High Altitude Himalayan Herbs. Part 20. A C‐19 Diterpenoid Alkaloid from Aconitum balfourii.
Authors: Khetwal K. S.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Efficient Conversion of Tomatidine into Neuritogenic Pregnane Derivative.
Authors: Matsushita Sayaka , Yanai Yoshihiro , Fusyuku Asami , Fujiwara Yukio , Ikeda Tsuyoshi , Ono Masateru , Han Chunguang , Ojika Makoto , Nohara Toshihiro
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Direct Stereocontrolled Synthesis of 3‐Amino‐3‐deoxy‐β‐Mannopyranosides: Importance of the Nitrogen Protecting Group on Stereoselectivity.
Authors: Crich David , Xu Huadong
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Host—Guest Interactions Involving Cyclodextrins: Useful Complementary Insights Achieved by Polarimetry.
Authors: Meo Paolo Lo , D'Anna Francesca , Riela Serena , Gruttadauria Michelangelo , Noto Renato
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Amphidinolactone B, a New 26‐Membered Macrolide from Dinoflagellate Amphidinium sp.
Authors: Takahashi Yohei , Kubota Takaaki , Kobayashi Jun'ichi
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Design, Synthesis, and Antiangiogenic Effects of a Series of Potent Novel Fumagillin Analogues.
Authors: Lee Hong Woo , Cho Chin Sung , Kang Sung Kwon , Yoo Yong Sang , Shin Jae Soo , Ahn Soon Kil
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Electronic, Magnetic and Transport Properties of Rare‐Earth Monopnictides
Authors: Duan Chun‐Gang , Sabirianov R. F. , Mei W. N. , Dowben P. A. , Jaswal S. S. , Tsymbal E. Y.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Epitaxial Growth and Surface Properties of Half‐Metal NiMnSb Films
Authors: Borca C. N. , Ristoiu D. , Jeong H.‐K. , Komesu Takashi , Caruso A. N. , Pierre J. , Ranno L. , Nozieres J. P. , Dowben P. A.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Zintl Ion[Pb10]2‐: a Rare Example of a Homoatomic Closo Cluster
Authors: Rose Michael J. , Mascharak Pradip K.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Coating Methods for Self‐Cleaning Thick Films of Titania
Authors: Abdullah H. Z. , Taib H. , Sorrell C. C.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Going to Extremes: “Super” Armed Glycosyl Donors in Glycosylation Chemistry
Authors: Jensen Henrik H. , Pedersen Christian Marcus , Bols Mikael
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Liquid‐Phase Catalytic Processing of Biomass‐Derived Oxygenated Hydrocarbons to Fuels and Chemicals
Authors: Chheda Juben N. , Huber George W. , Dumesic James A.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of Epoxyquinonoid Natural Products
Authors: Shoji Mitsuru
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Induction of Chirality in Sol—Gel Materials
Authors: Marx Sharon , Avnir David
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Evolution of Optimal Accuracy and Stability in Biological Systems
Authors: Holliday Robin
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Scientific Aspects of Polymer Electrolyte Fuel Cell Durability and Degradation
Authors: Borup Rod , et al. et al.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Hydrogen Production Reactions from Carbon Feedstocks: Fossil Fuels and Biomass
Authors: Navarro R. M. , Pena M. A. , Fierro J. L. G.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Membranes for Hydrogen Separation
Authors: Ockwig Nathan W. , Nenoff Tina M.
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Determination of Relative Configuration in Organic Compounds by NMR Spectroscopy and Computational Methods
Authors: Bifulco Giuseppe , Dambruoso Paolo , Gomez‐Paloma Luigi , Riccio Raffaele
Published: November 2007

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Characterization of Cytidine Derivatives that Inhibit the Kinase IspE of the Non‐Mevalonate Pathway for Isoprenoid Biosynthesis
Authors: Crane Christine M. , Hirsch Anna K. H. , Alphey Magnus S. , Sgraja Tanja , Lauw Susan , Illarionova Victoria , Rohdich Felix , Eisenreich Wolfgang , Hunter William N. , Bacher Adelbert , Diederich François
Published: November 2007

The enzymes of the non‐mevalonate pathway for isoprenoid biosynthesis are attractive targets for the development of novel drugs against malaria and tuberculosis. This pathway is used exclusively by the corresponding pathogens, but not by humans. A series of water‐soluble, cytidine‐based inhibitors that were originally designed for the fourth enzyme in the pathway, IspD, were shown to inhibit the subsequent enzyme, the kinase IspE (from Escherichia coli). The binding mode of the inhibitors was verified by co‐crystal structure analysis, using Aquifex aeolicus IspE. The crystal structures represent the first reported example of a co‐crystal structure of IspE with a synthetic ligand and confirmed that ligand binding affinity originates mainly from the interactions of the nucleobase moiety in the cytidine binding pocket of the enzyme. In contrast, the appended benzimidazole moieties of the ligands adopt various orientations in the active site and establish only poor intermolecular contacts with the protein. Defined binding sites for sulfate ions and glycerol molecules, components in the crystallization buffer, near the well‐conserved ATP‐binding Gly‐rich loop of IspE were observed. The crystal structures of A. aeolicus IspE nicely complement the one from E. coli IspE for use in structure‐based design, namely by providing invaluable structural information for the design of inhibitors targeting IspE from Mycobacterium tuberculosis and Plasmodium falciparum. Similar to the enzymes from these pathogens, A. aeolicus IspE directs the OH group of a tyrosine residue into a pocket in the active site. In the E. coli enzyme, on the other hand, this pocket is lined by phenylalanine and has a more pronounced hydrophobic character.
Identification of a Peripheral Substitution Symmetry Effect in Self‐Assembled Architectures
Authors: Ma Xiao‐Jing , Yang Yan‐Lian , Deng Ke , Zeng Qing‐Dao , Wang Chen , Zhao Ke‐Qing , Hu Ping , Wang Bi‐Qin
Published: November 2007

Two complementary classes of molecules based on a triphenylene core are synthesized. The two‐dimensional (2D) assemblies of these molecules deposited on a highly oriented pyrolytic graphite (HOPG) surface are identified with scanning tunneling microscopy (STM). Structures with large cavities are formed by symmetric molecules, while uniform and closely packed stripe‐assembled structures are obtained for asymmetric molecules. X‐ray diffraction (XRD) results support the observation of an ordered hexagonal columnar mesophase for symmetric molecules and a rectangular columnar mesophase for asymmetric molecules. The study demonstrates that the substitution symmetry has significant effects on the assembly characteristics of molecular architectures and also on the three‐dimensional (3D) macroscopic properties of the molecular materials.
Ruthenium(II)‐Catalyzed [2+2] Cycloadditions of anti 7‐Substituted Norbornenes
Authors: Jordan Robert W. , Le Marquand Paul , Tam William
Published: November 2007

The ruthenium(II)‐catalyzed [2+2] cycloadditions of anti 7‐substituted norbornenes with an alkyne were investigated. The cycloadditions were found to proceed with a high degree of stereoselectivity, giving only the exo stereoisomers in moderate to good yields using an improved protocol. Comparative rate studies between a variety of anti 7‐substituted norbornenes and an alkyne revealed that the reactivity of the alkene component decreases dramatically as the alkene becomes more electron deficient.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Redox‐Active Catechol‐Functionalized Molecular Rods: Suitable Protection Groups and Single‐Molecule Transport Investigations
Authors: Weibel Nicolas , Błaszczyk Alfred , von Hänisch Carsten , Mayor Marcel , Pobelov Ilya , Wandlowski Thomas , Chen Fang , Tao Nongjian
Published: November 2007

The synthesis of molecular rod 1 comprising a central redox‐active unit and two terminal acetyl‐protected sulfur groups is reported. Various protecting groups for the catechol moiety were investigated and protected precursors 14–18 were synthesized. In particular, ethyl orthoformate 17 can be easily and selectively deprotected in mild acidic conditions ruling out the need for a strong Lewis acid like boron tribromide. The redox activity of 1 was confirmed by cyclic voltammetric investigations. Gold–molecule–gold junctions were formed with the dimethyl‐protected rod 18. Single‐molecule transport investigations using this molecular rod revealed a set of three single‐junction conductance values varying over two orders of magnitude.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Safety and efficacy of 90Y radiotherapy for hepatocellular carcinoma with and without portal vein thrombosis
Authors: Kulik Laura M. , Carr Brian I. , Mulcahy Mary F. , Lewandowski Robert J. , Atassi Bassel , Ryu Robert K. , Sato Kent T. , Benson Al , Nemcek Albert A. , Gates Vanessa L. , Abecassis Michael , Omary Reed A. , Salem Riad
Published: November 2007

This study was undertaken to present data from a phase 2 study in which patients with unresectable hepatocellular carcinoma (HCC) with and without portal vein thrombosis underwent radioembolization with Yttrium (90Y) microspheres. Patients treated were stratified by Okuda, Child-Pugh, baseline bilirubin, tumor burden, Eastern Cooperative Oncology Group (ECOG), presence of cirrhosis and portal vein thrombosis (PVT) (none, branch, and main). Clinical and biochemical data were obtained at baseline and at 4-week intervals following treatment for up to 6 months. Tumor response was obtained using computed tomography (CT). Patients were followed for survival. One hundred eight patients were treated during the study period. Thirty-seven (34%) patients had PVT, 12 (32%) of which involved the main PV. The cumulative dose for those with and without PVT was 139.7 Gy and 131.9 Gy, respectively. The partial response rate using world Health Organization (WHO) criteria was 42.2%. Using European Association for the Study of the Liver (EASL), the response rate was 70%. Kaplan-Meier survival varied depending on location of PVT and presence of cirrhosis. The adverse event (AE) rates were highest in patients with main PVT and cirrhosis. There were no cases of radiation pneumonitis.

Conclusion:

The use of minimally embolic 90Y glass microspheres to treat patients with HCC complicated by branch/lobar PVT may be clinically indicated and appears to have a favorable toxicity profile. Further investigation is warranted in patients with main PVT. (Hepatology 2007.)