bluuebunny/crossref_metadata_2025 huggingface dataset:
VprBP (DCAF1) Regulates RAG1 Expression Independently of Dicer by Mediating RAG1 Degradation
Authors: Schabla N. Max , Perry Greg A. , Palmer Victoria L. , Swanson Patrick C.
Published: June 2018

The assembly of Ig genes in developing B lymphocytes by V(D)J recombination is initiated by the RAG1–RAG2 endonuclease complex. We previously identified an interaction between RAG1 and viral protein R binding protein (VprBP) (also known as DNA damage binding protein 1 cullin 4–associated factor 1 [DCAF1]), a substrate receptor for the cullin 4–really interesting new gene (RING) E3 ubiquitin ligase (CRL4). We report in this article that in mice, B cell–intrinsic loss of VprBP increases RAG1 protein levels and disrupts expression of the endoribonuclease Dicer, which is essential for microRNA maturation. Rag1/2 transcription is known to be derepressed by loss of microRNA-mediated suppression of phosphatase and tensin homolog, raising the possibility that the elevated level of RAG1 observed in VprBP-deficient B cells is caused indirectly by the loss of Dicer. However, we show that VprBP restrains RAG1 expression posttranscriptionally and independently of Dicer. Specifically, loss of VprBP stabilizes RAG1 protein, which we show is normally degraded via a mechanism requiring both 20S proteasome and cullin–RING E3 ubiquitin ligase activity. Furthermore, we show that RAG1 stabilization through small molecule inhibition of cullin–RING E3 ubiquitin ligase activation promotes V(D)J recombination in a murine pre–B cell line. Thus, in addition to identifying a role for VprBP in maintaining Dicer levels in B cells, our findings reveal the basis for RAG1 turnover and provide evidence that the CRL4VprBP(DCAF1) complex functions to maintain physiological levels of V(D)J recombination.
Genome instability in Chironomus annularius sensu Strenzke (Diptera, Chironomidae): A biomarker for assessment of the heavy metal contaminants in Poland
Authors: Michailova Paraskeva , Ilkova Julia , Szarek-Gwiazda Ewa , Kownacki Andrzej , Ciszewski Dariusz
Published: June 2018

We studied the effect of heavy metal contaminations on genome instability of Chironomus annularius sensu Strenzke from three sampling sites on the River Chechło valley in southern Poland and a control site in Saraya, Bulgaria. The analysis of the heavy metal concentrations in sediments at the three river sites indicated concentrations higher than those in the fossil reference data (Zn 83-160 times, Pb 64-250 times, and Cd 210-793). According to the geoaccumulation index (Igeo), the sediments at all Chechło stations were classified as extremely polluted (Igeo class 6) by Cd, Pb and Zn while they were much less polluted by Cu (classes 1-3). The concentration of Cd, Pb and Zn in the sediments studied exceeded 21-79, 11-44 and 18-34 times the toxic effect threshold (TET) respectively; therefore, the sediments potentially have detrimental effects on the fauna. Genome instability was determined by somatic structural chromosome alterations (mainly heterozygous inversions) in the salivary gland chromosomes of C. annularius. On the basis of the number and frequency of these aberrations the somatic (S) and cytogenetic (C) indices were calculated as these indices allow a better quantification of the impact of heavy metals on organisms living in sediments. In the three Chechło sampling sites somatic aberrations occurred at a frequency significantly higher than in the control site (P<0.001). The three Chechło samples possess a high spectrum of somatic rearrangements with S index varying from 1.5 to 2.23 while in control site, S is 1.08. The C index of C. annularius from the polluted river sites varied from 0.163 to 0.380, far in excess of the C value of the control site (1.0), indicating strong pollution (<0.5) according to previous studies. In addition, a high level of inherited aberrations was detected (19 inherited band sequences, two of which were new). In all river stations the inverted homozygous band sequences A2.2 occurred in a high frequency (85%) and no standard sequences (A1.1) were observed. The transcription activity of Nucleolar Organizers (NORs) in chromosome arms A, C, E, G was often damaged and NOR activity was completely suppressed in 12.48% of larvae. Moreover, appearance of malformations in the external morphology of larvae was detected in 16.67% of larvae from all polluted sites. Therefore, the genome instability as estimated by two cytogenetic indices is a good biomarker of long-term toxicity and could be successfully implemented in the sediment monitoring procedures.
Communities of Chironomidae (Diptera) from four ecological zones delimited by the Mediterranean coastal ecosystems of Morocco (Moroccan Rif). Updated list and faunal data from the last two decades
Authors: Kettani Kawtar , Moubayed-Breil Joel
Published: June 2018

Based on a large material collected during the last two decades in 43 sites covering a wide range of habitats (fresh and brackish water) we delimited four ecological zones, which extend between sea level and high mountain areas located above 1000 m. The four ecological zones are: Zone 1 (Estuarine zone including pools, ponds, lagoons and wet meadows, altitude 0-10 m); Zone 2 (Potamal, alt. 10-350 m); Zone 3 (Lower basin of streams and wadis (alt. 350-1000 m); Zone 4 (Upper basin of streams, wadis, springs and peat bogs, alt. > 1000 m). An updated list of 256 species/taxa belonging to Chironomidae (Diptera) has been established which complements previous data for the chironomid fauna of Morocco. The list includes 72 (28%) new records for the fauna of Morocco, 21 (8%) undescribed species and probably 2 new genera (1 Orthocladiinae and 1 Tanytarsini). Spatial distribution of species by subfamilies is highlighted in the four ecological zones where faunal comparative results are: Buchonomyinae (1 species); Tanypodinae (21); Diamesinae (8); Orthocladiinae (143); Chironominae (82, including 40 Chironomini and 42 Tanytarsini). Currently, a total of 410 valid species are reported from Morocco. The low frequency of both listed and undescribed species in Mediterranean coastal ecosystems is linked to the limited faunal knowledge of wetland coastal areas and fragility of lowland habitats, which are regarded as true hotspots.
Chironomidae fauna of springs in Iceland – assessing the ecological relevance behind Tuxen’s spring classification
Authors: Kreiling Agnes-Katharina , Ólafsson Jón S. , Pálsson Snæbjörn , Kristjánsson Bjarni K.
Published: June 2018

In 1937, S. L. Tuxen studied the animal community of hot springs in Iceland, and classified springs according to their relative temperature into cold, tepid, and hot. Eighty years after Tuxen’s study, we revisited some of the hot springs in Skagafjörður, Northern Iceland. Our aim was to compare the invertebrate community of 1937 and today, and to assess the stability of hot spring habitats over the years. To test Tuxen’s spring classification on an ecological basis, we furthermore collected chironomid larvae from 24 springs of a broad range of temperature, with samples taken both at the surface area of the spring and at the groundwater level. The chironomid species composition of hot springs differed from that of cold and tepid springs. Whereas Cricotopus sylvestris, Arctopelopia sp., and Procladius sp. characterised the chironomid community in Icelandic hot springs, cold and tepid springs were dominated by Eukiefferiella minor, Orthocladius frigidus and Diamesa spp. Community composition analyses and the exclusive occurrence of taxa in one of the temperature classes validated the ecological relevance of Tuxen’s spring classification for the chironomid species community. Both environmental parameters and invertebrate community of Icelandic hot springs seem to be the same as 80 years ago. Although springs have the potential to provide stable habitats, they are currently under high anthropogenic pressure, and should be increasingly considered in nature conservation.
Profile of refractive error in Ekiti, south western Nigeria
Authors: Ajayi Iyiade A. , Omotoye Olusola J. , Omotoso-Olagoke Olubunmi
Published: June 2018

Background: Refractive error is one of the eye disorders with the capability of causing visual impairment. We needed to know the various types and proportion of refractive errors seen in patients attending an eye clinic at the tertiary health centre.Aim: An observational study was carried out to determine the profile of refractive error in a southwestern Nigeria hospital.Methods: All new cases with the diagnosis of refractive error between January 2015 and December 2016 had autorefraction and subjective refraction to determine the types and values of refractive error. Data were analysed with SPSS 20. Statistical significance was inferred at p < 0.05.Results: Refractive error constituted 618 (21.4%) of the total new cases. The mean age was 39.3 ± 22.96 years. The male to female ratio was 1:1.8. Children constituted 25.7% of all the cases. The most common refractive error was myopia in 64.3%. A total of 312 (50.5%) patients had other co-existing ocular disorders with allergic conjunctivitis on the top of the list. The number of visually impaired reduced to 70 (5.64%) after the correction of existing refractive error with about 94.1% having their visual acuity restored to normal.Conclusion: Refractive error was a common eye disorder among our patients with the proportion of children about a quarter of all patients. We recommend that childhood refractive errors should be given prioritised attention in eye outreach programmes.
Tuberculosis manifested as Parinaud’s oculoglandular syndrome
Authors: Mataswa Ngaatendwe , Masanganise Rangarirai
Published: June 2018

A 5-year-old male patient presented to the Sekuru Kaguvi Eye Hospital (SKH) with a painful discharging right eye (RE) for 1 year. Two months prior to presentation, he developed a non-productive cough, night sweats and loss of weight. On examination, a granulomatous follicular conjunctivitis and a corneal phlyctenule were noted in the RE, as well as ipsilateral preauricular lymphadenopathy. In collaboration with the paediatricians, a diagnosis of Parinaud’s oculoglandular syndrome (POGS) as a manifestation of tuberculosis was made. This is the first reported case of POGS and tuberculosis in Zimbabwe.
On the discrepancy of HCl processing in the core of the wintertime polar vortices
Authors: Grooß Jens-Uwe , Müller Rolf , Spang Reinhold , Tritscher Ines , Wegner Tobias , Chipperfield Martyn P. , Feng Wuhu , Kinnison Douglas E. , Madronich Sasha
Published: June 2018

Abstract. More than 3 decades after the discovery of the ozone hole, the
processes involved in its formation are believed to be understood in
great detail. Current state-of-the-art models can reproduce
the observed chemical composition in the springtime polar stratosphere,
especially regarding the quantification of halogen-catalysed ozone
loss.
However, we report here on a discrepancy between simulations and
observations during the less-well-studied period of the onset of
chlorine activation. During this period, which in the Antarctic is
between May and July, model simulations significantly overestimate
HCl, one of the key chemical species, inside the polar vortex during
polar night. This HCl discrepancy is also observed in the Arctic.
The discrepancy exists in different models to varying extents; here,
we discuss three independent ones, the Chemical Lagrangian
Model of the Stratosphere (CLaMS) as well as the Eulerian
models SD-WACCM (the specified dynamics version of the Whole Atmosphere
Community Climate Model) and TOMCAT/SLIMCAT. The HCl discrepancy points to
some unknown process in the formulation of stratospheric chemistry
that is currently not represented in the models. We characterise the HCl discrepancy in space and time for the
Lagrangian chemistry–transport model CLaMS, in which HCl in the
polar vortex core stays about constant from June to August in the
Antarctic, while the observations indicate a continuous HCl decrease
over this period. The somewhat smaller discrepancies in the Eulerian
models SD-WACCM and TOMCAT/SLIMCAT are also presented. Numerical
diffusion in the transport scheme of the Eulerian models is
identified to be a likely cause for the inter-model differences.
Although the missing process has not yet been identified, we
investigate different hypotheses on the basis of the characteristics
of the discrepancy.
An underestimated HCl uptake into the polar stratospheric cloud (PSC) particles that consist
mainly of H2O and HNO3 cannot explain it due to
the temperature correlation of the discrepancy. Also, a direct
photolysis of particulate HNO3 does not resolve the discrepancy
since it would also cause changes in chlorine chemistry in late
winter which are not observed.
The ionisation caused by galactic cosmic rays provides an additional
NOx and HOx source that can explain only about 20 %
of the discrepancy.
However, the model simulations show that a hypothetical
decomposition of particulate HNO3 by some other process not
dependent on the solar elevation, e.g. involving galactic cosmic
rays, may be a possible mechanism to resolve the HCl discrepancy.
Since the discrepancy reported here occurs during the beginning of
the chlorine activation period, where the ozone loss rates are small,
there is only a minor impact of about 2 % on the overall ozone
column loss over the course of Antarctic winter and spring.
A chemical transport model study of plume-rise and particle size distribution for the Athabasca oil sands
Authors: Akingunola Ayodeji , Makar Paul A. , Zhang Junhua , Darlington Andrea , Li Shao-Meng , Gordon Mark , Moran Michael D. , Zheng Qiong
Published: June 2018

Abstract. We evaluate four high-resolution model simulations of pollutant
emissions, chemical transformation, and downwind transport for the Athabasca
oil sands using the Global Environmental Multiscale – Modelling Air-quality
and Chemistry (GEM-MACH) model, and compare model results with surface
monitoring network and aircraft observations of multiple pollutants, for
simulations spanning a time period corresponding to an aircraft measurement
campaign in the summer of 2013. We have focussed here on the impact of
different representations of the model's aerosol size distribution and
plume-rise parameterization on model results. The use of a more finely resolved representation of the aerosol size
distribution was found to have a significant impact on model performance,
reducing the magnitude of the original surface PM2.5 negative biases
32 %, from −2.62 to −1.72 µg m−3. We compared model predictions of SO2, NO2, and speciated
particulate matter concentrations from simulations employing the commonly
used Briggs (1984) plume-rise algorithms to redistribute emissions from large
stacks, with stack plume observations. As in our companion paper (Gordon et
al., 2017), we found that Briggs algorithms
based on estimates of atmospheric stability at the stack height resulted in
under-predictions of plume rise, with 116 out of 176 test cases falling below
the model : observation 1 : 2 line, 59 cases falling within a factor of 2
of the observed plume heights, and an average model plume height of 289 m
compared to an average observed plume height of 822 m. We used a
high-resolution meteorological model to confirm the presence of significant
horizontal heterogeneity in the local meteorological conditions driving plume
rise. Using these simulated meteorological conditions at the stack locations,
we found that a layered buoyancy approach for estimating plume rise in stable
to neutral atmospheres, coupled with the assumption of free rise in
convectively unstable atmospheres, resulted in much better model performance
relative to observations (124 out of 176 cases falling within a factor of 2
of the observed plume height, with 69 of these cases above and 55 of these
cases below the 1 : 1 line and within a factor of 2 of observed values).
This is in contrast to our companion paper, wherein this layered approach
(driven by meteorological observations not co-located with the stacks) showed
a relatively modest impact on predicted plume heights. Persistent issues with
over-fumigation of plumes in the model were linked to a more rapid decrease
in simulated temperature with increasing height than was observed. This in
turn may have led to overestimates of near-surface diffusivity, resulting in
excessive fumigation.
Tropical atmospheric circulation response to the G1 sunshade geoengineering radiative forcing experiment
Authors: Guo Anboyu , Moore John C. , Ji Duoying
Published: June 2018

Abstract. We investigate the multi-Earth system model response of
the Walker circulation and Hadley circulations under the idealized solar
radiation management scenario (G1) and under abrupt4xCO2. The Walker
circulation multi-model ensemble mean shows changes in some regions but no
significant change in intensity under G1, while it shows a 4∘
eastward movement and 1.9 × 109 kg s−1 intensity
decrease in abrupt4xCO2. Variation in the Walker circulation intensity has
the same high correlation with sea surface temperature gradient between the
eastern and western Pacific under both G1 and abrupt4xCO2. The Hadley
circulation shows significant differences in behavior between G1 and
abrupt4xCO2, with intensity reductions in the seasonal maximum northern and
southern cells under G1 correlated with equatorward motion of the
Intertropical Convergence Zone (ITCZ). Southern and northern cells have a
significantly different response, especially under abrupt4xCO2 when impacts
on the southern Ferrel cell are particularly clear. The southern cell is
about 3 % stronger under abrupt4xCO2 in July, August and September than
under piControl, while the northern is reduced by 2 % in January,
February and March. Both circulations are reduced under G1. There are
significant relationships between northern cell intensity and land
temperatures, but not for the southern cell. Changes in the meridional
temperature gradients account for changes in Hadley intensity better than
changes in static stability in G1 and especially in abrupt4xCO2. The
difference in the response of the zonal Walker circulation and the meridional
Hadley circulations under the idealized forcings may be driven by the zonal
symmetric relative cooling of the tropics under G1.
Differentiating diffuse auroras based on phenomenology
Authors: Grono Eric , Donovan Eric
Published: June 2018

Abstract. There is mounting evidence which suggests that pulsating auroral patches
often move with convection. This study is an initial step at identifying the
differences between patches that move with convection and those that do not.
While many properties of pulsating patches vary, here we outline criteria for
separating pulsating auroral patches into three categories based on two
properties: their structural stability and the spatial extent of their
pulsations. Patchy aurora is characterized by stable structures whose
pulsations are limited to small regions. Patchy pulsating aurora consists of
stable patches whose pulsations are far less subtle and occur throughout much
of their area. Amorphous pulsating auroral structures are unstable – very
rapidly evolving – and can pulsate over their entire area. The speed with
which amorphous pulsating aurora evolves makes their motion difficult to
ascertain and seems unrelated to the E×B drifting of
cold, equatorial plasma.
Central-Pacific surface meteorology from the 2016 El Niño Rapid Response (ENRR) field campaign
Authors: Hartten Leslie M. , Cox Christopher J. , Johnston Paul E. , Wolfe Daniel E. , Abbott Scott , McColl H. Alex
Published: June 2018

Abstract. During the early months of the 2015/2016 El Niño event, scientists led by the Earth System Research Laboratory's Physical Sciences Division conducted the National Oceanic and Atmospheric Administration's (NOAA's) El Niño Rapid Response (ENRR) field campaign. One component of ENRR involved in situ observations collected over the near-equatorial eastern–central Pacific Ocean. From 25 January to 28 March 2016, standard surface meteorology observations, including rainfall, were collected at Kiritimati Island (2.0° N, 157.4° E) in support of twice-daily radiosonde launches. From 16 February to 16 March 2016, continuous measurements of surface meteorology, sea surface temperature, and downwelling shortwave radiation were made by NOAA Ship Ronald H. Brown. These were largely done in support of the four to eight radiosondes launched each day as the ship travelled from Hawaii to TAO buoy locations along longitudes 140 and 125° W and then back to port in San Diego, California. The rapid nature of these remote field deployments led to some specific challenges in addition to those common to many surface data collection efforts. This paper documents the two deployments as well as the steps taken to evaluate and process the data. The results are two multi-week surface meteorology data products and one accompanying set of surface fluxes, all collected in the core of the eastern–central Pacific's extremely warm waters. These data sets, plus metadata, are archived at the NOAA's National Centers for Environmental Information (NCEI) and are free for public access: surface meteorology from Kiritimati Island (https://doi.org/10.7289/V51Z42H4); surface meteorology and some surface fluxes from NOAA Ship Ronald H. Brown (https://doi.org/10.7289/V5SF2T80; https://doi.org/10.7289/V58050VP).
Ship- and island-based soundings from the 2016 El Niño Rapid Response (ENRR) field campaign
Authors: Hartten Leslie M. , Cox Christopher J. , Johnston Paul E. , Wolfe Daniel E. , Abbott Scott , McColl H. Alex , Quan Xiao-Wei , Winterkorn Matthew G.
Published: June 2018

Abstract. As the 2015/2016 El Niño was gathering strength in late 2015, scientists at the Earth System Research Laboratory's Physical Sciences Division proposed and led the implementation of the National Oceanic and Atmospheric Administration's (NOAA's) El Niño Rapid Response (ENRR) Field Campaign. ENRR observations included wind and thermodynamic profiles of the atmosphere over the near-equatorial eastern central Pacific Ocean, many of which were collected from two field sites and transmitted in near-real time for inclusion in global forecasting models. From 26 January to 28 March 2016, twice-daily rawinsonde observations were made from Kiritimati (pronounced Christmas) Island (2.0° N, 157.4° E; call sign CXENRR). From 16 February to 16 March 2016, three to eight radiosondes were launched each day from NOAA Ship Ronald H. Brown (allocated call sign WTEC) as it travelled southeast from Hawaii to service Tropical Atmosphere Ocean (TAO) buoys along longitudes 140 and 125° W and then north to San Diego, California. Both the rapid and remote nature of these deployments created particular difficulties in collecting and disseminating the soundings; these are described together with the methods used to reprocess the data after the field campaign finished. The reprocessed and lightly quality-controlled data have been put into an easy-to-read text format, qualifying them to be termed Level 2 soundings. They are archived and freely available for public access at NOAA's National Centers for Environmental Information (NCEI) in the form of two separate data sets: one consisting of 125 soundings from Kiritimati (https://doi.org/10.7289/V55Q4T5K), the other of 193 soundings from NOAA Ship Ronald H. Brown (https://doi.org/10.7289/V5X63K15). Of the Kiritimati soundings, 94 % reached the tropopause and 88 % reached 40 hPa, while 89 % of the ship's soundings reached the tropopause and 87 % reached 40 hPa. The soundings captured the repeated advance and retreat of the Intertropical Convergence Zone (ITCZ) at Kiritimati, a variety of marine tropospheric environments encountered by the ship, and lower-stratospheric features of the 2015–2016 QBO (quasi-biennial oscillation), all providing a rich view of the local atmosphere's response to the eastern central Pacific's extremely warm waters during the 2015/16 El Niño.
Earthquakes on the surface: earthquake location and area based on more than 14 500 ShakeMaps
Authors: Lackner Stephanie
Published: June 2018

Abstract. Earthquake impact is an inherently interdisciplinary topic that receives
attention from many disciplines. The natural hazard of strong ground motion
is the reason why earthquakes are of interest to more than just
seismologists. However, earthquake shaking data often receive too little
attention by the general public and impact research in the social sciences.
The vocabulary used to discuss earthquakes has mostly evolved within and for
the discipline of seismology. Discussions on earthquakes outside of
seismology thus often use suboptimal concepts that are not of primary
concern. This study provides new theoretic concepts as well as novel
quantitative data analysis based on shaking data. A dataset of relevant
global earthquake ground shaking from 1960 to 2016 based on USGS ShakeMap
data has been constructed and applied to the determination of past ground
shaking worldwide. Two new definitions of earthquake location (the shaking
center and the shaking centroid) based on ground motion parameters are
introduced and compared to the epicenter. These definitions are intended to
facilitate a translation of the concept of earthquake location from a
seismology context to a geographic context. Furthermore, the first global
quantitative analysis on the size of the area that is on average exposed to
strong ground motion – measured by peak ground acceleration (PGA) – is
provided.
How CPED Guiding Principles and Design Concepts Influenced the Development and Implementation of an EdD Program
Authors: Buss Ray R.
Published: June 2018

In this essay, I have described how the CPED Guiding Principles for Program Design (GPPD) and Design Concepts (DC) have influenced the development and implementation of Arizona State University’s EdD in Leadership and Innovation program.  I have explained the pervasive influence of the CPED GPPD and DC on various aspects of the program including (a) more general or global aspects of the program; (b) signature pedagogies of the program; (c) development of program milestones; and (d) development and implementation of courses in the program.  As a result, faculty members have created and continue to deliver a more coherent, practitioner-oriented program, which benefits students and is guided by the CPED Principles and Design Concepts.
Problems of Practice As Stance
Authors: Hamann Edmund 'Ted' , Trainin Guy
Published: June 2018

This piece describes a steadily changing, teacher leadership-oriented, CPED-affiliated, education doctorate (EdD) program that is housed in a department of curriculum and instruction. It situates the program design in relation to four key concepts—epistemology, praxis, efficacy, and iterative processes—while highlighting CPED’s core stance that the voice of the professional practitioner needs to be inserted into discussion of educational change, not as the target of policy, nor the object of research, but rather as a coequal partner in a research/policy/ practice triad in which practitioner insights related to context are key for the viability of educational efforts.
The Wife of Bath's Bele Chose
Authors: Bjork Robert E.
Published: June 2018

The Wife of Bath's famous erudition, resistance to authority, and unapologetic sexuality all come together in one of Chaucer's epithets for her private parts. Bele chose (beautiful thing) occurs only three times: in Chaucer's prologue to the Wife of Bath's Tale, in a Middle English translation of a Latin medical text, and—the present paper argues—in the Roman de la Rose. Chaucer uses the term as a deliberate repudiation of pudendum (shameful thing), a term that he does not use but which was undoubtedly known to him through several classical and medieval sources. A survey of all Chaucer's euphemisms for private parts in the Wife of Bath's Prologue contextualizes the discussion.
Effects of linguistic context on the acceptability of co-speech gestures
Authors: Zlogar Christina , Davidson Kathryn
Published: June 2018

We ask whether iconic co-speech gestures are judged as more natural by naive participants when their content is entailed by a preceding context, or repeated in the same utterance, or when they contribute new information (i.e., are nontrivial). Our results show, first, that the acceptability of co-speech gestures is not affected by whether they are entailed by a preceding context (they are not “hard presupposition triggers”). In contrast, our second finding is that gestures are affected by content in the same utterance, such that they are judged more acceptable when they reinforce information already present in the proposition. In addition, gestures varied widely in how acceptable they were judged even in the same information contexts, which we take to be an indication that we are just scratching the surface of a more general question about the felicity of co-speech gestures, of which the current study provides a first experimental foundation.
Aumento de coroa clínica – relato de caso
Authors: Lourenço Aneliese Holetz de Toledo , Júnior Evandro De Toledo Lourenço , Da Silva Viviane Cardoso
Published: June 2018

Objetivo: a Odontologia moderna busca corresponderàs expectativas e às demandas estéticas atuais, garantindo,entretanto, a manutenção da saúde e da função.Alguns indivíduos têm um sorriso esteticamente comprometidopela excessiva exposição gengival, caracterizandoo quadro de sorriso gengival. Relato de caso:o presente estudo revisa e discute a análise do sorrisogengival apresentando um caso clínico ilustrativoda técnica de aumento de coroa clínica por demandaestética. São abordados tópicos correlatos como: conceitode sorriso harmônico, diferentes técnicas de aumentode coroa clínica e sua indicação, medicação prée pós-operatória, procedimentos técnicos cirúrgicos econtrole pós-operatório. O resultado, demonstrado porfotografias clínicas e alcançado por meio da cirurgiaperiodontal, permitiu atingir o almejado pela demandado paciente. Considerações finais: conclui-se que atécnica da cirurgia periodontal para aumento da coroaclínica e tratamento do sorriso gengival, quando oportunamenteindicada e tecnicamente executada, proporcionaum resultado positivo com relação aos anseiosdo paciente.
Palavras-chave: Estética. Periodontia. Sorriso gengival.
Osteonecrose mandibular associada ao uso de bisfosfonatos tratada com plasma rico em fibrina leucocitária: relato de caso
Authors: Duque Maria Gisela Buitrago , Ribeiro Ana Sofia , Burzlaff João Batista , Silveira Vinicius Salim , Tonietto Leonardo , Calcagnotto Thiago
Published: June 2018

Bisfosfonatos são antiabsortivos que agem especificamentesobre a atividade dos osteoclastos. Uma complicaçãograve do seu uso é a osteonecrose dos maxilares,definida como uma área de exposição óssea na regiãomaxilofacial sem resolução espontânea por um períodode no mínimo oito semanas em pacientes com históricode uso de compostos bisfosfonatos, mas que não foramsubmetidos à radioterapia na região de cabeça e pescoço.Tratamentos conservadores são recomendados, masos resultados da literatura são controversos e nem sempreefetivos. Por isso, novas abordagens, como o usodos concentrados plaquetários, têm sido sugeridas. Sãoprodutos autólogos que contém altas concentrações defatores de crescimento e que atuam como moléculasde adesão celular, acelerando o reparo ósseo. Objetivo:descrever, por meio de relato de caso, o uso do plasmarico em fibrina e leucocitária (L-PRF) como forma detratamento da osteonecrose mandibular. Relato do caso:paciente do gênero feminino, 79 anos, diagnosticadacom osteonecrose mandibular associada ao uso de bisfosfonatos,tratada por meio de cirurgia convencionalassociando curetagem óssea e rotação de retalho, massem sucesso. Então, foi submetida à modificação detécnica cirúrgica, associando o uso de plasma rico emfibrina leucocitária (L-PRF), a fim de acelerar o processode reparo ósseo e garantir a cicatrização dos tecidosmoles. Considerações finais: o uso de L-PRF como tratamentoda osteonecrose mandibular estimula o reparoósseo e acelera a cicatrização dos tecidos moles, sendouma alternativa eficaz de tratamento.
Palavras-chave : Bisfosfonatos. L-PRF. PRF. Osteonecrose.
Cirurgia ortognática para tratamento da síndrome de apneia obstrutiva do sono: relato de caso
Authors: Panissa Constanza , Morawski Rafael , Tonietto Leonardo , Silveira Vinicius Salim , Gulinelli Jessica Lemos , Calcagnotto Thiago
Published: June 2018

Objetivo: ilustrar, por meio de um caso clínico, os benefíciosdo tratamento da síndrome de apneia obstrutivade sono (Saos) por intermédio da cirurgia ortognáticabimaxilar, com o uso de biomateriais de reconstrução.Relato de caso: paciente encaminhado para avaliaçãode discrepância maxilomandibular em relação àbase do crânio e para avaliação de queixa de roncointenso durante a noite e intenso cansaço diurno. Apósavaliação e exames complementares, o paciente foidiagnosticado com apneia obstrutiva do sono; assim,foi realizada a cirurgia de avanço bimaxilar como terapêuticaresolutiva para o caso. Considerações finais:a Academia Americana de Medicina do Sono (AAMS)define Saos como uma doença que se caracteriza porepisódios repetitivos de obstrução total (apneia) ou parcial(hipopneia) das vias aéreas superiores durante osono. A cirurgia de avanço bimaxilar se apresenta comouma das melhores opções terapêuticas para os pacientescom essa síndrome. A cirurgia ortognática, incluindoseus diversos procedimentos, provoca importantesmudanças nas diferentes zonas das vias aéreas faríngeas.A cirurgia ortognática de avanço bimaxilar commentoplastia de avanço foi eficaz, em longo prazo, notratamento da Saos, e o uso simultâneo de biomateriaisde substituição óssea aumenta a estabilidade óssea primária,acelera o processo de reparo ósseo e diminui amorbidade pós-operatória.
Palavras-chave: Apneia obstrutiva do sono. Avançomaxilar. Cirurgia ortognática.
CRESCIMENTO E BIOMASSA DE INDIVÍDUOS JOVENS DE Cabralea canjerana (Vell.) Mart.
Authors: Lanzarin Karina , Fleig Frederico Dimas , Meyer Evandro Alcir , Pereira Lilian Daniel , Schöder Thomas , Lisboa Gerson Santos
Published: June 2018

Este trabalho possui como objetivo ajustar e selecionar modelos matemáticos capazes de estimar o incremento periódico em área basal, o volume e biomassa de indivíduos jovens de Cabralea canjerana (Vell.) Mart. O estudo foi desenvolvido no município de Agudo - RS, em uma área de Floresta Estacional Decidual. Para análise de crescimento foram utilizadas 19 árvores. A quantificação da biomassa foi obtida pelo método direto com 14 árvores da espécie. No cálculo de volume foram selecionadas e cubadas 12 árvores pelo método de Smalian. Na modelagem da estimativa das variáveis incremento periódico em área basal, volume, biomassa total, biomassa da madeira e biomassa foliar foram testados seis modelos matemáticos. Para avaliação das equações ajustadas foi utilizada a menor soma dos escores dos critérios estatísticos: coeficiente de determinação, erro padrão da estimativa e coeficiente de variação em percentagem, em conjunto com a análise gráfica da dispersão dos resíduos. O modelo matemático de Schumacher-Hall obteve melhor ajuste nas estimativas de incremento periódico em área basal, volume, biomassas total e da madeira. A equação definida para o incremento periódico em área basal foi lnIPg=-0,149+1,777.lnDAP-0,815.lnHt. A equação de volume selecionada foi lnV=-9.382+1.583.lnDAP+1.064.lnHt. As equações definidas para biomassa aérea total e biomassa da madeira foram lnBt=-3,769+1,779.lnDAP+1,131lnHt e lnBm=-3,986+1,784.lnDAP+1,198lnHt, respectivamente. As equações para estimativa de biomassa foliar obtiveram estatísticas insatisfatórias e apresentaram elevados valores de coeficiente de variação em percentagem.
ESTIMATIVA DA BIOMASSA FOLIAR E POTENCIAL EXTRATIVISTA DA PIMENTA Pseudocaryophyllus (CATAIA)
Authors: Loyola Eisfeld Rozane , Ansolin Roni Djeison , D’Angelis Amanda Silva Rocha , Silva Júnior Edson Rangel , Costa Filho Sérgio Vinícius Serejo da
Published: June 2018

Pimenta pseudocaryophyllus (Gomes) Landrum (cataia) é uma espécie da família Myrtaceae de importância econômica e cultural. Suas folhas são consideradas um produto florestal não madeireiro (PFNM), sendo extraídas para produção de aguardente, conhecida como “whisky caiçara”. O presente estudo teve como objetivo testar modelos matemáticos com a finalidade de gerar estimativas da biomassa seca foliar da espécie. Foram utilizados dados de biomassa seca foliar de 23 indivíduos de cataia, obtidos por meio de determinações diretas pelo método destrutivo. Todas as árvores amostradas foram medidas quanto ao CAP (circunferência à altura do peito), diâmetro e altura de copa, altura total e número de brotações. Os resultados mostraram que o melhor modelo, empregando a variável número de brotações, obteve um erro de estimativa de 16%, já os demais, obtiveram erros superiores a 30%. Por fim, o modelo Stepwise Completo apresentou o melhor desempenho para a variável dependente biomassa seca das folhas. Ainda, a extração das folhas de P. pseudocaryophyllus é uma atividade econômica e cultural das famílias tradicionais da comunidade de Ilha Comprida, cujo manejo sustentável pode contribuir na perpetuação e preservação da espécie.
Analysis Grid of Adjustment Strategies of Non-profit Organizations Benefiting From Microcredit to the Constraints of Microfinance Institutions: The Case of Burundi
Authors: Nduwayo Marie-Goreth , Sayumwe Michel
Published: June 2018

Based on the work of Henderson and Venkatraman (1993) on strategic alignment, the objective of this article is to explain that the strategic alignment of microcredit beneficiary not for profit Organizations (NPOs) is achieved through their adjustment to the constraints of their lessors. We thus discuss the adaptation of Burundian NPOs benefiting from microcredit by taking into account a specific attribute of a difficult economic environment: the threat of their survival. The physiological needs of their members are at the origin of their reactions of adaptation to the constraints of the lessor. This adaptation enables them to acquire and maintain the resources necessary for their survival. This article explains this adaptation by highlighting the strategic actions of the members of the NPOs who are beneficiaries of microcredit.
Integrating semantic and fuzzy dimensions into electronic medical records: Case of cerebral palsy information system
Authors: Ghorbel Hanen , Farjallah Sirine
Published: June 2018

The meta-modeling of medical records helps standardize and capitalize the expert’s knowledge domain. It promotes the interoperability knowledge and the reuse of clinical concepts, i.e., archetypes. It also promotes high quality electronic medical record system (EMRS) design, which helps provide better care service delivery. As a result, different standards of medical informatics use the dual model to support interoperability between Medical Information Systems. We particularly quote ISO/EN 13606 and OpenEHR. However, the use of these standards still presents challenges. Apart from political reasons, the main obstacles to the adoption of these standards include: (1) a lack of guides and methodological tools to facilitate the construction of EMRS using two conceptual levels. Designers must have languages, approaches and tools to assist them in the modeling of archetypal EMRS; (2) a lack of methodologies for semantic activities on the content of electronic health records in the semantic web environment; (3) and a lack of management of uncertainties and inaccuracies that may exist in the medical field. Theconstruction of an approach to modeling EMRS according to the dual model approach, considering the uncertainties, inaccuracies and semantics of these systems, is a difficult task, given the challenges to emancipate. In literature, we don’t find such an approach. We, therefore, defined one in this paper. Our goal is to guide the designer in all stages of developing a new generation of EMRS, from analysis and specification of requirements to implementation. To achieve this goal, we have created an approach to support the following activities: (1) clinical concepts and information management and meta-modeling in accordance with the openEHR standard, (2) integration of the semantic dimension into EMRS considered to enable the execution of semantic activities in the semantic web environment; and (3) integration of the fuzzy dimension into electronic medical record data structures. As a contribution, we defined an approach called Fuzzy SemanticOpenEHR allowing the integration of semantic and fuzzy dimensions into EMRS modeled using the openEHR standard. Fuzzy SemanticOpenEHR intends to help and equip the designer during the different phases of creating a fuzzy ontology. Thanks to the mechanisms offered by this approach, we have been able to obtain a fuzzy ontological basis that can serve as a knowledge base that can support the semantic interoperability between EMRS, the deduction of new knowledge and the taking of knowledge’s clinical decision. To test our contribution, we proceeded to the realization of a prototype of tools realized for the pediatric neurology service of the university hospital “Hédi Chaker Sfax - Tunisia” and the association of the handicapped persons safeguard of Sfax. This prototype is a framework called “XML 2 FuzzyOWL”. Then, we tested this framework using a case of a disease which is “Cerebral Palsy”.
Capturing acute stress disorder in the trauma population
Authors: Delle Janelle Marie , King Joan E.
Published: June 2018

Acute Stress Disorder (ASD) is classified as a psychiatric diagnosis that was first introduced to the DSM-IV in 1994. It was introduced to describe acute stress reactions that precede Post-Traumatic Stress Disorder (PTSD). ASD usually occurs within the first month after the occurrence of a traumatic event. Early recognition of ASD is crucial from both an early treatment standpoint and avoidance of progressing to PTSD, especially in the trauma population, as late recognition can lead to long-term mental and physical suffering. At this time, there is no protocol for screening of ASD upon admission to a Level I trauma center in the Southeast in the Unites States. Hence, not all trauma patients are assessed for ASD. Often, acute stress is recognized several days after admission, with late referrals to the psychiatric team for psychological evaluation and treatment. This late psychiatric referral often leads to the patient’s inability to participate in physical rehabilitation due to stress and anxiety, thus increasing hospital stay and use of resources. Thus, collaborating between the primary medical team and psychiatry team is essential and facilitates the recovery process for potential acute or long-term psychiatric disorders. To determine if ASD was recognized in the trauma population at a large Level I Trauma Center in the Southeast, and if referrals to psychiatry were initiated in a timely manner, this quality improvement study was developed. The data from this study served to correlate the percentage of patients who screened positive for ASD on admission to a sub-acute trauma floor.  A standardized tool called The Stanford Acute Stress Reaction Questionnaire (SASRQ) was used to determine the frequency of ASD in this trauma population. We also ascertained if the trauma nurse practitioners (NPs) had requested a psychiatric referral without the use of the SASRQ tool.  Findings included 18 of the 50 trauma patients who had screened positive for ASD (36%). It was found that of those 18 patients who screened positive for ASD, 2 patients received a psychiatric consultation for evaluation and treatment. These findings suggest a needed focus of capturing ASD early in the admission process, using a validated screening tool, along with early psychological intervention to aid in prevention of PTSD post-discharge.
The Impact of Providing Computer Language Experience on the Reading Readiness among Preschool Children
Authors: Hamad Ali Ahmad Bani
Published: June 2018

This study aim to identify the effect of computer literacy on reading readiness among preschool children. The study sample consisted of (49) preschool children studying at the First University Kindergarten distributed into to two groups: experimental and control. The language experience of the experimental group was presented to students through using the computer for two years. A program has been designed for this purpose  using the Multimedia Builder software. In order to answer the study questions, the mathematical averages, standard deviations, ANCOVA and MANCOVA analysis were used.  The results of the study showed that there was an effect of computer experience in the six dimensions of reading readiness (visual recognition, auditory distinction, understanding, information, auditory recall, and visual recall) and this effect is related to the group variable. However, there were no statistically significant effect of sex variable over all the dimensions of the Reading readiness scale.
Una salida al dualismo: Juego y trabajo en John Dewey
Authors: Rodríguez Sabariz Carlos
Published: June 2018

Desde la antigüedad hasta hoy mismo, el juego y el trabajo han sido habitualmente vistos como dos actividades antitéticas y sustancialmente heterogéneas. Sin embargo, John Dewey juzgó que esta concepción común constituía uno más de los dualismos contraproducentes y perniciosos en los que estamos inmersos. Si pensamos en la actitud mental con la que abordamos esas actividades, comprenderemos sus profundas conexiones y llegaremos a apreciar la necesidad de su confluencia. Este artículo examina, pues, la respuesta de Dewey a la visión dualista del jugar y el trabajar, así como la manera en la que materializa esa respuesta en el campo pedagógico. Para ello, basó el programa de estudios de su Escuela Experimental, no en el seguimiento pasivo de una serie de asignaturas, sino involucrando a los alumnos en la realización de unas «ocupaciones activas».
Manuel Fraijó Nieto, Avatares de la creencia en Dios
Authors: Del Olmo Ibáñez María
Published: June 2018

Recensión sobre el último libro de Manuel Fraijö publicado en Trotta: "Avatares de la creencia en Dios
Aspectos musicales en la crítica deleuziana de la representación
Authors: Lucero Guadalupe
Published: June 2018

En este artículo nos proponemos recorrer la crítica deleuziana del concepto de representación a partir del valor y utilidad del concepto estético de forma. Para ello analizaremos no sólo el concepto en el interior de su filosofía, sino también el sentido del mismo en términos estéticos en el marco de la teoría del arte. La hipótesis de este artículo es que a través de una lectura musical del concepto de forma es posible considerar su función en su vecindad y distancia respecto del concepto de estructura.
La «desinstantaneización» del instante. Análisis de la noción de «instante-sitio» en los Beiträge zur Philosophie de Martin Heidegger
Authors: Garrido Maturano Ángel Enrique
Published: June 2018

RESUMEN: El artículo analiza la noción de “instante-sitio” en los Beiträge zur Philosophie a través de la reconstrucción de la noción de abismo como modo ontohistórico (seinsgeschichtlich) de acaecer del ser y de rehusamiento-itinerante (zögernde-Versagung) como espacio-temporalización del abismo.  El análisis procura, en primer lugar, explicitar  en qué medida la perspectiva de los Beiträge revierte la relación entre decisión y situación de Ser y tiempo a causa de la identificación del instante-sitico con la situación ontohistórica. En segundo, muestra en qué sentido la concepción extática  del “instante-sitio” en el pensar del ser como Ereignis implica una des-instantaneización del fenómeno.
El concepto de solidaridad y su multiplicidad semántica. A la memoria de Toni Domènech
Authors: Bertomeu María Julia
Published: June 2018

El propósito de este trabajo es tomar prestado un aspecto (parcial) de la  perspectiva metodológica koselleckiana  para:1. inquirir sobre algunos de los “estratos semánticos” contemporáneos que se articulan en la idea político-jurídico de  solidaridad y2. sondear si acaso el periodo de eclipse del concepto moderno de fraternidad -y del esplendor de la idea de solidaridad en el discurso político y social -, podrían ser considerados como un momento de “fractura entre el espacio de la experiencia y el horizonte de expectativa” en el sentido de las dos principales categorías de análisis de Koselleck.