bluuebunny/crossref_metadata_2025 huggingface dataset:
Endothelial Cells Promote Docetaxel Resistance of Prostate Cancer via FGF2/ERG/Akt/mTOR Signaling Pathway
Authors: Zhou Wen-Hao , Su Yi-Ming , Zhang Yu , Han Bang-Min , Liu Hai-Tao , Wang Xiao-Hai
Published: July 2020

Background

Docetaxel is a first-line chemotherapy for the treatment of patients with castration-resistant prostate cancer (CRPC). Despite the good initial response of docetaxel, drug resistance will inevitably occur. Mechanisms underlying docetaxel resistance are not well elaborated. Endothelial cells (ECs) have been implicated in the progression and metastasis of prostate cancer (PCa). However, little attention has been paid to the role of ECs in the development of docetaxel resistance in PCa.
Methods

Here, we sought to investigate the function and mechanism of ECs involving in the docetaxel resistance of PCa. The 22Rv1 and C4-2B PCa cell lines were cultured with or without human umbilical vein endothelial cells (HUVEC). The proliferation of each PCa cell line was assessed by CCK8 and EdU assays. Cell viability of each PCa cell line treated with docetaxel was evaluated by CCK8. Apoptosis was measured by flow cytometry. Quantitative reverse transcription (RT)-PCR assay was used to determine the expression of ETS related gene (ERG) in each PCa cell line and FGF2 in HUVEC. The proteins including ERG, Caspase3, PARP, Akt, p-Akt, mTOR and p-mTOR were quantified by western blotting. ERG overexpressing C4-2B cells(C4-2B-ERG) were constructed by transfection with pLenti6.3-ERG lentivirus. C4-2B-ERG cells were knocked down by transfecting with ERG siRNAs. Differentially expressed cytokines between the serum-free media from 22Rv1 and 22Rv1/HUVEC co-culture system were detected by human cytokine array and determined by ELISA assay. Tumors were induced in mice by injecting 22Rv1 cells with or without HUVEC and treated with docetaxel. Tumor growth and apoptosis were examined by immunohistochemistry and TUNEL respectively.
Results

ECs promoted proliferation and inhibited apoptosis in PCa cells (in vitro) and mouse xenograft tumors induced by these cells (in vivo) under docetaxel treatment. ECs secreted FGF2 to induce ERG expression and activate the Akt/mTOR signaling pathway in PCa cells contributing to docetaxel resistance. Blocking FGF2 could reverse the enhancing effects of HUVEC on docetaxel resistance in PCa cells. Inhibition of the Akt/mTOR signaling pathway could alleviate chemoresistance mediated by ERG.
Conclusion

ECs promote docetaxel resistance via FGF2/ERG/Akt/mTOR signaling pathway in PCa cells. Targeting FGF/ FGFR signaling may represent a promising therapeutic strategy to overcome docetaxel resistance.
The COX10-AS1/miR-641/E2F6 feedback loop is involved in the progression of glioma
Authors: Liu Liang , Li Xiaojian , Wu Heming , Tang Yong , Li Xiang , Shi Yan
Published: July 2020

Background

Glioma is the most common primary tumour of the central nervous system and is considered one of the greatest challenges for neurosurgery. Mounting evidence has shown that lncRNAs participate in various biological processes of tumours, including glioma. This study aimed to reveal the role and relevant mechanism of COX10-AS1 in glioma.
Methods

The expression of COX10-AS1, miR-641 and E2F6 was measured by qRT-PCR and/or western blot. Clone formation assays, EdU assays, Transwell assays and tumour xenograft experiments were performed to evaluate the effects of COX10-AS1, miR-641 and E2F6 on glioma proliferation, migration and invasion. Luciferase reporter assays, RNA pull-down assays and ChIP assays were conducted to analyse the relationship among COX10-AS1, miR-641 and E2F6.
Results

First, we demonstrated that COX10-AS1 was upregulated in glioma tissues and cell lines, which was related to the grade of glioma and patient survival. Next, through functional assays, we found that COX10-AS1 influenced the proliferation, migration and invasion of glioma cell lines. Then, with the help of bioinformatics analysis, we confirmed that COX10-AS1 regulated glioma by acting as a sponge of miR-641 to regulate E2F6. Moreover, further study indicated that E2F6 could promote COX10-AS1 expression by binding to its promoter region.
Conclusions

COX10-AS1 acts as an oncogene in combination with COX10-AS1/miR-641/E2F6 in glioma, which may be beneficial to the diagnosis and treatment of glioma.
TRIM11 promotes the proliferation, migration and chemoresistance of anaplastic thyroid cancer by stabilizing YAP
Authors: Tang Jianing , Tian Zelin , Liao Xing , Cui Qiuxia , Wu Gaosong
Published: July 2020

Background

Anaplastic thyroid cancer (ATC) is one of the most aggressive and virulent solid tumors. The ubiquitin proteasome system presents in all eukaryotic cells and is essential for cellular homeostasis. While its underlying role in ATC remains largely unclear. TRIM11 is an E3 ubiquitin ligase and has been reported to act as an oncogene in several human cancers. The present study aims to reveal the oncogenic function of TRIM11 in ATC.
Methods

Western blot was used to measure the protein expression of TRIM11 and YAP, while the YAP target genes were measured by real-time PCR. CCK8 assay was used to detect cell viability; wound-healing assay and transwell assay were used to measure the migration ability of ATC. The xeno-graft tumor model was used for in vivo study. RNA sequencing was analyzed by Ingenuity Pathway Analysis. Protein stability assay was used to detect YAP protein degradation. Immuno-precipitation assay was used to detect the interaction domain between YAP and TRIM11. The ubiquitin-based Immuno-precipitation assays were used to detect the specific ubiquitination manner happened on YAP.
Results

TRIM11 depletion significantly decreases cell proliferation and migration capabilities of ATC cells, and elevates cell sensitivity to chemotherapy. The effects induced by TRIM11 depletion could be rescued by further YAP overexpression. Depletion TRIM11 decreases YAP protein level and YAP/TEAD target genes, such as CTGF, ANKRD1 and CYR61 in ATC. Immuno-precipitation assay shows that TRIM11 associates with YAP, promoting YAP stabilization possibly via inducing YAP mono-ubiquitination. Further mechanistic analysis indicates that the RING domain of TRIM11 interacts with the WW domain of YAP and promotes its mono-ubiquitination, thus prolongs YAP protein half.
Conclusions

Our study describes the oncogenic function of TRIM11 in ATC, which acts as a post-translational modulating factor of Hippo pathway. Targeting TRIM11 could be a promising therapeutic method for ATC treatment.
The impact of the COVID-19 Pandemic on Patients with Chronic Rheumatic Diseases: A Study in 15 Arab Countries
Authors: Ziade Nelly , Kibbi Lina el , Hmamouchi Ihsane , Abdulateef Nizar , Halabi Hussein , Hamdi Wafa , Abutiban Fatemah , Rakawi Manal el , Eissa Mervat , Masri Basel
Published: July 2020

Aim. To evaluate the impact of the Coronavirus Disease 2019 pandemic (COVID-19) on the access to rheumatology care for patients with chronic rheumatic diseases (CRD) in the Arab countries.Method. A web-based cross-sectional survey was designed by the Arab Adult Arthritis Awareness group (AAAA) consisting of 16 rheumatologists representing countries from the Arab League of Associations for Rheumatology (ArLAR), and was validated by the ArLAR scientific committee. The survey was disseminated through social media and patients' associations' channels between May 8 and May 22, 2020. The steering committee developed recommendations to improve the care of patients with CRD during the COVID-19 pandemic.Results. A total of 2163 patients were included in the analysis; 72% were females; mean age was 40 years (SD 11.9). The Levant, the Gulf, and North Africa contributed almost equally to the sample. The pandemic had a significant negative impact on rheumatology visits in 82% of cases, on access to hydroxychloroquine (47%), and on chronic medication persistency (28%). The negative impact on rheumatology visits was associated with female gender, country, medication non-persistency, isolation due to COVID-19, and impact on mental health. Sixty-one patients (2.8%) stated that they had COVID-19, 5% said that a close contact was infected, and 47% were in isolation because of COVID-19.Conclusion. The current study highlights the deleterious consequences of the COVID-19 pandemic on the continuity of rheumatology care. Therefore, an action plan, including establishing a telemedicine platform, securing drug availability, and promoting medication persistence through the appropriate communication channels, is strongly recommended.
Principios metafísicos fundamentales de la cosmología chamánica abyayalense
Authors: Hernández Rodríguez Juan Camilo
Published: July 2020

En el presente texto se hará una exposición general de los principales principios metafísicos que fundamentan la cosmología abyayalense colombiana. Para cumplir tal cometido se realizarán los siguientes pasos: primero, plantear el tipo de acercamiento filosófico que se puede establecer con la cosmología abyayalense; segundo, identificar los compromisos ontológicos de dicha cosmología, identificándola como monista (la realidad-naturaleza es una), pero internamente múltiple y en devenir; tercero, elucidar qué tipo de relaciones fundamentales permiten que se consoliden estructuras cósmicas (es decir, de «ordenamiento»), tanto a nivel macro como a nivel micro, a partir del concepto ‘ley de origen’ (en arhuaco: kunsamu); y, finalmente, esbozar la idea del chamán como aquel ser que transita por esa compleja estructura cósmica para proteger el territorio.
Complacência, irresolução, fraternidade
Authors: Pellejero Eduardo
Published: July 2020

Desnudando as formas que ganham o espaço e o tempo quando o real devém imagem, e o modo singular que adota o nosso pensamento quando se abre ao que as imagens dão a pensar, a fenomenologia da experiência estética da conta, não apenas das relações que estabelecem as nossas faculdades quando contemplamos sem objeto nem fim o que se oferece à nossa sensibilidade, mas também de uma utopia que abre os modos em que vemos, pensamos e fazemos o mundo a um futuro sem determinação. Utópicas pareceram ser, de fato, as coordenadas que a definem: a suspensão de qualquer interesse que vá além das dimensões aspetuais dos objetos da experiência, a momentânea colocação entre parêntese de qualquer saber prévio que possa facilitar a sua apreensão, a irresolução da atividade teleológica que governa os nosso impulsos cognitivos. O presente artigo pretende demonstrar que essas determinações transcendentais são, em todo o caso, algo mais do que uma ideia abstrata ou um ideal teórico, e que as nossas práticas contemplativas e criativas encontram-se sempre, em maior ou menor medida, perpassadas por elas, pertencendo manifestamente à ordem do comum.
Tratamento e análise de resíduos da produção de açaí: um estudo sob a ótica da ecoeficiência
Authors: Moreira Márcia Athayde , Ferreira de Sousa Ana Lidia
Published: July 2020

Objetivo: Esta pesquisa teve como principal objetivo levantar junto aos estabelecimentos de venda de açaí da Região Metropolitana de Belém – PA (RMB), qual tratamento está sendo designado aos resíduos (caroços de açaí), tendo como parâmetros de análise o ponto de vista contábil e o socioambiental, sob a ótica da Política Nacional de Resíduos Sólidos (PNRS), dentro de um contexto de ecoeficiência.

Metodologia:  Foi realizada pesquisa exploratória, transversal, por meio de levantamento, junto à 80 estabelecimentos de produção de açaí da RMB.

Resultados: Os resultados apontaram que os respondentes, em parte, possuem conhecimento acerca da gestão socioambiental e do que é impacto socioambiental, entretanto, não possuem plano de gerenciamento de resíduos sólidos, e, na percepção da maioria deles, a obrigatoriedade de realizar a correta destinação dos caroços de açaí é da prefeitura, o que demonstra desconhecimento acerca das diretrizes da PNRS. Quanto ao tratamento dos resíduos do açaí, a maioria respondeu que os caroços são destinados a aterros, a despeito das possibilidades de reaproveitamento. Quando analisado o tratamento dos resíduos pela ótica contábil-financeira, observou-se como inexistente, o que pode estar associado com o tipo de formalização (ou a sua falta) e o fato de não terem apoio profissional para realizar a gestão do negócio.

Contribuições do Estudo: O presente trabalho visa contribuir para a discussão acerca da importância de estabelecer planos de incentivo e/ou orientação para o reaproveitamento, para que os empreendedores de açaí possam desfrutar dos benefícios financeiros e melhor contribuir para a redução dos impactos ambientais, realizando uma gestão ecoeficiente.
Tax saving strategies: Udi Bolos’ Case
Authors: Larissa Ribeiro Soares  , Sabrina Rafaela Pereira Borges
Published: July 2020

Purpose: Udi Bolos’ case discusses tax planning and the best taxation regime to be adopted by a small company.

Methodology: This case uses tax contents and also presents discussions about tax evasion and tax avoidance, showing elements of an ethical-accounting dilemma experienced by many family businesses.

Results: Entrepreneur at Udi Bolos, Mr. Marcelo, seeking to reduce his costs, receives two divergent opinions from two accountants: to act within tax legality or to withhold tax. After a careful analysis, the owner realized it is possible to obtain legal savings for the business with a good tax planning.

Contributions of the Study: The present case encourages students’ critical reflection on taxation regimes in order to reduce the tax burden paid by companies, being useful for learning concepts in disciplines associated with tax and cost analysis. In addition, ethical reflections are carried out on the accountant’s role in the provision of information and manipulation of economic and financial data.
ANAIS DA “IV JORNADA NORDESTINA DE ALIMENTAÇÃO E NUTRIÇÃO”
Authors: GARCIA LIGIA
Published: July 2020

A Jornada Nordestina de Alimentação e Nutrição (JORNAN), sediada em Santa Cruz-RN desde 2012, é um evento promovido pelos professores do curso de graduação em Nutrição da Faculdade de Ciências da Saúde do Trairi (FACISA), da Universidade Federal do Rio Grande do Norte, que vem se consolidando ao longo dos anos na região do Nordeste brasileiro, sempre levando temas relevantes para profissionais da saúde, pesquisadores, docentes, discentes e sociedade, se configurando assim como um importante recurso de disseminação da informação científica.

No ano de 2018 foi realizada a IV edição da JORNAN e, contando com a presença de palestrantes nacionais, o evento comemorou 10 anos de existência FACISA, um marco para a educação de excelência do campi da saúde no interior do Rio Grande do Norte. Neste contexto, foi com muita satisfação que aceitamos prefaciar esta edição da Revista Ciência Plural que traz em destaque publicações desse evento, premiando assim os esforços de todos os autores envolvidos.

A VI JORNAN teve como tema central Tradição, Atualidades e Vivências em Alimentação e Nutrição, e foi um cenário de bastante reflexão e estudo que perpassou as diferentes áreas de atuação do nutricionista com o foco para Marcadores Nutricionais na prática Clínica, Gestão e Empreendedorismo, Nutrição Social e Grupos Minoritários e a experiência exitosa do Projeto Horta Comunitária Nutrir e o Direito a Alimentação Adequada.
UM AUTO RELATO SOBRE A PARTICIPAÇÃO NO PROJETO ATELIÊ DO SORRISO: UM CAMINHO PERCORRIDO DA EXTENSÃO À SOCIEDADE
Authors: De Oliveira Eriberto Esdras
Published: July 2020

Introdução: A extensão universitária oportuniza experiências únicas ao estudante, inserindo-o em diferentes contextos, fora do ambiente fechado de uma faculdade, proporcionando vivências em cenários reais, enfrentando públicos distintos, que o preparam para o mercado de trabalho, para a vida, para o mundo. O projeto Ateliê do Sorriso, maior projeto de extensão com finalidade educativo/preventiva do Departamento de Odontologia da Universidade Federal do Rio Grande do Norte, cuja finalidade é levar educação em saúde bucal a idosos, adultos, crianças, pessoas com necessidades especiais e demais, buscando ajudar essas clientelas a desenvolverem autonomia e autocuidado com a saúde bucal/saúde geral. Objetivo: Relatar uma experiência pessoal, descrevendo o papel que esse projeto teve na minha formação profissional e no preparo que me proporcionou, transformando-me em promotor de saúde na minha rotina laboral. Metodologia: A partir das estratégias metodológicas usadas no Ateliê (planejamento e avaliação de ações educativas e de saúde, formação de lideranças, gestão, comunicação oral, dentre outras), com atividades práticas sempre ancoradas no lúdico, os discentes de odontologia aprendem a trabalhar em vários cenários, desenvolvendo habilidades e competências necessárias ao novo perfil profissional em saúde. Resultados e Discussão: Esse projeto serviu e continua servindo como base no preparo dos futuros profissionais que venham a fazer parte da Estratégia Saúde da Família, proporcionando vivências únicas de aprendizado. Conclusão:  Com todas as atividades e treinamentos desenvolvidos, o projeto habilitou-me a vivenciar a saúde na família, nas visitas domiciliares, a atuar no programa saúde na escola, no grupo hiperdia, em programas de rádio (saúde no rádio) e demais atividades de educação/prevenção em saúde bucal, sobre as quais nem sempre fomos preparados em sala de aula. Finalmente, posso afirmar que a extensão tem um grande papel na formação e nesse sentido, deve continuar sendo um pilar fundamental, pois proporciona oportunidades ímpares de aprendizado e trocas de saberes.

Palavras-chave: extensão comunitária; universidade; estratégia saúde da família.
EXPERIÊNCIA DE ATUAÇÃO INTERPROFISSIONAL DO DENTISTA NA ESTRATÉGIA SAÚDE DA FAMÍLIA
Authors: Figueirêdo Renan Cabral de , Melo Ricardo Henrique Vieira de , Rodrigues Maísa Paulino , Souza Georgia Costa de Araújo , Vilar Rosana Lúcia Alves de
Published: July 2020

Introdução: O acompanhamento do Crescimento e Desenvolvimento (CD) faz parte do escopo de ações desenvolvidas na Atenção Primária à Saúde e tem por propósito a saúde integral da criança. A atenção/assistência odontológica, iniciadas nos primeiros meses de vida, impacta positivamente sobre a saúde bucal e geral. Objetivo: O estudo objetivou compreender a atuação dos cirurgiões-dentistas no acompanhamento do crescimento e desenvolvimento infantil, no contexto da Estratégia Saúde da Família, em um município de médio porte. Metodologia: Trata-se de um estudo qualitativo, do tipo compreensivo-interpretativo, cujos participantes foram os dentistas atuantes no município referido. Os instrumentos de coleta foram: questionário semiestruturado, grupo focal e diário de campo. Os dados, apoiados pelo software ALCESTE, foram submetidos à análise temática de conteúdo. Resultados: Emergiram duas categorias: concepções sobre o CD; e ações desenvolvidas durante o CD. A saúde bucal aparece como potencialidade na atenção e assistência à saúde infantil, fortalecendo o processo de cuidar. Conclusões: Verificou-se o predomínio de percepções ancoradas em fundamentos que reduzem as dimensões subjetivas, culturais e sociais dos sujeitos, demonstrando distanciamento de uma prática interprofissional efetiva. Palavras-Chave: Saúde Bucal. Crescimento e Desenvolvimento. Estratégia Saúde da Família.
PROCEDIMENTO OPERACIONAL PADRÃO NA ASSISTÊNCIA NUTRICIONAL AO PACIENTE COM COVID 19: RELATO DE EXPERIÊNCIA
Authors: Teixeira Suerda Isa Nascimento , Barros de Oliveira Laíse Mayara , Dos Santos Ikson Rauan , Ferreira Pinheiro Josilene Maria , Dantas de Araújo Oliveira Márcia Regina , Dantas de Lira Niethia Regina , Martins Bezerra Furtado Mariana Câmara Martins Bezerra Furtado , De Oliveira Silva Ferreiro Machado Rosana
Published: July 2020

Introdução: Vivencia-se na atualidade uma pandemia causada pelo novo Coronavírus, o qual é transmitido por meio de gotículas de saliva, espirro e tosse, fazendo-se necessário mudanças na assistência ao paciente. Objetivo: Descrever a experiência com a construção de um Procedimento Operacional Padrão para assistência nutricional em pacientes acometidos pelo Coronavírus. Metodologia: Trata-se de um estudo descritivo, do tipo relato de experiência, vivenciado pela equipe de residentes multiprofissionais em nutrição do Hospital Universitário Onofre Lopes, da Universidade Federal do Rio Grande do Norte. Resultados: Baseado nas recomendações da Organização Mundial de Saúde e do Conselho Federal de Nutrição e, com a participação dos profissionais do serviço, foi construído o referido procedimento que descreve as boas práticas na triagem, avaliação e conduta nutricional. Conclusão: A implantação e implementação do POP oportunizou a interação de conhecimentos e novas condutas assistenciais, mesmo diante das limitações estruturais, de equipamentos de proteção individual e de medidas de contingenciamento implementadas no serviço.

Palavras-chave: Protocolos clínicos; Assistência à Saúde; Integralidade em Saúde; Infecções por Coronavírus.
Green Chemistry and Green Solvents: An Overview
Authors: Devi Barla Karuna , Naraparaju Swathi , Soujanya Chaganti , Gupta Sayan Dutta
Published: July 2020

Green chemistry emphasizes designing novel routes to overcome health and environmental problems that occur during a chemical reaction. Green solvents are used in place of conventional solvents that are hazardous to both human and the environment. Solvents like water, ionic liquids, supercritical CO2, biosolvents, organic carbonates, and deep eutectic mixtures can be used as green solvents. The review focuses on the properties, applications, and limitations of these solvents.
Hibridaciones de saberes y lógicas culturales en la pesca
Authors: Florido del Corral David
Published: July 2020

The goal of this paper is to reflect upon the processes of knowledge construction of Andalusian fishermen (Southern Spain), linked to diverse forms of material and cognitive appropriation systems of marine environment. Making use of a set of anthropological concepts embedded in the post-structuralist and ontological turns, I seek to explain the relational modes –both practical and cognitive, that link organically the poles of Nature and Culture, so that their limits are dissolved (Naturo-cultural relationships). The analysis is based on three main axes: community, relationality and the role of technological artifacts in these relational webs of knowledge. After this conceptualization, it is discussed whether we could consider this cultural model as an ontology, in particular its forms of environmental knowledge. Finally it is proposed to reorient the normative systems of fisheries management, promoting a dialogue: on one hand, between the traditional and scientific knowledge; on the other hand, between artisanal/traditional patterns and industrialized and market economies at the Southern coast of Chile. Thus, the focus is placed on the hybridization of practices and knowledge, as well as on the consequences of their combinations in the political and economic fields.
Operaciones balleneras tradicionales en las costas sudamericanas
Authors: Quiroz Daniel
Published: July 2020

Historians distinguish two major categories in commercial whaling, with a technological regime specific: traditional and modern whaling. The use of vessels, open boats, manual harpoons and spears defines traditional whaling, and modern whaling by the presence of whale catchers armed with an explosive harpoon gun mounted on its bow. In traditional whaling, two varieties, "Basque" and "Yankee", which come in South America at different times, operates on pre-existing knowledge and practices (processing of whales and/or hunting properly) in the local coastal communities. The presence of foreign whalers makes it possible to explain the emergence of local operations in Brazil, Chile and Peru, which successfully integrates technological, social and productive elements of the visiting groups with their own in a complex set of transformations and continuities, constituting "local whaling traditions". Our studies have been focused on the Chilean case, but the literature tell us if the Brazilian and Peruvian experiences are "different" or "similar" to the Chilean experiences, considering their exposure to foreign influences. Traditional Atlantic and Pacific whaling operations show a lot of technological similarities but some organizational differences, especially in terms of the relevance of private initiative and the role of the State.
Pesca artesanal, economía e intermediación en litoral del sur austral chileno
Authors: Saavedra Gallo Gonzalo , Navarro Pacheco Magdalena
Published: July 2020

In this article we start by examining the relationship established historically by the inhabitants of the coast of austral Chile with economic agents – entrepreneurs or brokers – whose demand stoked exploitation of the abundant natural resources of this area, mainly wood, mammal skins and fish, from at least the middle of the nineteenth century. The work, based on an ethnographic study, leads up to the problematisation of the current and/or contemporary state of the dynamics of these strongly rooted relationships, in the time-honoured form of brokerage, a critical factor in artisanal fishing systems.
TEACHING READING THROUGH RECIPROCAL TEACHING METHOD
Authors: Hamdani Beny
Published: July 2020

This paper aims to investigate whether the university students who are taught reading through Reciprocal Teaching Method achieve better in reading ability than those who are taught through Direct Reading Thinking Activities. The design of this study is a quasi-experimental, non-randomized control group, pretest-posttest since it is conducted in a classroom setting that the subjects have been organized into classes. The subject of the study was the fourth term of university students of English education study program consisting 30 university students. The instrument of this research was a test as Pre-test and Post-test in the form of reading comprehension questions. The data analysis used Independent T-Test. Based on the result of the calculation of post-test from experimental and control groups, the alternative hypothesis (Ha) was accepted. The result of the study shows that the use of the Reciprocal Teaching Method can improve the university students’ reading ability. It proves the hypothesis of the study that students who are taught reading through the Reciprocal Teaching method achieve better in reading ability than those who are taught through Direct Reading Thinking Activities. Based on this result, it can be concluded that the Reciprocal Teaching Method can be used as an alternative method to teach reading, so that the students are able to understand the texts comprehensively. It also makes the university students more active in the teaching learning process and can improve their ability as well.
THE HAGUE CONVENTION ON THE INTERNATIONAL PROTECTION OF ADULTS: OVERVIEW AND CONVERGENCE WITH THE BRAZILIAN LAW
CONVENÇÃO DA HAIA SOBRE A PROTEÇÃO INTERNACIONAL DE ADULTOS: PANORAMA E REFLEXOS SOBRE O ORDENAMENTO BRASILEIRO
Authors: Rodrigues Diogo Luiz Cordeiro , Costa Igor Pires Gomes da
Published: July 2020

This article aims to give an overview of the Hague Convention on the International Protection of Adults, focusing on its scope as well as its rules of jurisdiction and those relating to applicable law. Moreover, based on the Brazilian case, this work discusses to what extent some underlying reasons for the Convention may indicate a degree of convergence between national and international rules regarding vulnerable adults.
ETAPAS DE APLICAÇÃO DOS PRINCÍPIOS DO ART. 4º DA CONSTITUIÇÃO FEDERAL
STAGES IN THE APPLICATION OF PRINCIPLES FROM ART. 4 OH THE FEDERAL CONSTITUTION
Authors: Massaú Guilherme Camargo
Published: July 2020

O texto tem como objetivo expor algumas etapas na aplicação dos princípios constitucionais das relações internacionais (Art. 4º), pelo fato de este ser tema pouco explorado pela doutrina pátria, e também, por significar um artigo estratégico no constitucionalismo brasileiro. Ele é estratégico por conter valores-princípios que o Estado brasileiro deve, necessariamente, observar enquanto estiver se relacionando com outros Estados ou órgãos internacionais. A política internacional adotada pelo Presidente da República (Chefe de Estado) deve estar consoante com os princípios constitucionais. Dessa forma, o texto traz etapas da aplicação do Art. 4º da CF a fim de mostrar uma das possibilidades de efetivação do artigo em análise. Nesse sentido, deve se considerar os três Poderes como possíveis intérpretes desse dispositivo constitucional, o que dependerá da circunstância em que ocorrer a aplicação. Emprega-se o método de abordagem analítico com o objetivo analisar critérios fundamentais que devem incidir na aplicação dos princípios constitucionais das relações internacionais. A pesquisa baseou-se no método de pesquisa bibliográfico, já que se trata de uma projeção de método interpretativo de princípios.
DUE PROCESS OF LAW IN EUROPEAN UNION’S ECONOMIC SANCTIONS: THE RESPONSE TO UKRAINIAN CRISIS
DEVIDO PROCESSO DE LEI NAS SANÇÕES ECONÔMICAS DA UNIÃO EUROPEIA: A RESPOSTA À CRISE UCRANIANA
Authors: Bijos Leila , Oliveira Luiz Fernando de , Bragança Thainá Ferreira Monteiro de
Published: July 2020

This article focuses on the economic sanctions and the listing process in the light of due process of law, as well as the legitimacy of the European Union to impose such sanctions under international law. It has a qualitative approach, using the methodology of documental analysis (particularly the documents from the European Union Council and Commission) and bibliographical research. Since 2014 the European Union has imposed restrictive measures against the Russian Federation in response to the annexation of Crimea and Sevastopol, as well as ‘destabilization’ of Ukraine.  Due to the imposition of these measures, 159 persons were subject to assets freezing and visa bans; 41 entities had their assets frozen in the EU; also including economic sanctions such as the limitation of Russian state-owned financial institutions to the European capital markets; and the access to ‘sensitive’ technologies, particularly in the energetic and military industries. As a conclusion, the listing process has improved considerably in the past years to align itself with the principle of due process. Critically, it is indicated the need to allow the targets to be heard and present their defense before any measures taken and in urgent matters which by its nature demand inaudita alteram parte decisions, the provision of injunctive relief.
La discreción o el arte de desaparecer
Authors: Paláu Castaño Luis Alfonso
Published: July 2020

Pierre Zaoui

«Abrid un día suavemente la puerta de la habitación de vuestros hijos. Los encontráis en el fondo de la pieza, jugando por una vez sin tropeles entre ellos, lejos del sostén y del juicio de los adultos, quizás libres, tal vez alienados, qué importa. Si no tenéis hijos, tratad de sorprender a vuestro amante o a vuestra amante cuando se está durmiendo, es un poco lo mismo. Pues, en los dos casos, qué goce profundo. Ellos no se dan cuenta de tu presencia, no se sienten observados, gozan consigo mismos, dedicados enteramente a la inmanencia de su juego o de su sueño. Si de repente lo aperciben, entonces todo está perdido, pues todo regresará en un periquete en el circo ordinario de la vanidad de los egos, de la rivalidad de las miradas, de la dialéctica mediocre del reconocimiento o de la seducción. Pero mientras no pase esto, algo extraordinario se gana: un momento de amor sin recompensa, no necesariamente muy intenso, pero de una serenidad incomparable.»
Reseña del libro La democracia a través de los derechos: el constitucionalismo garantista como modelo teórico y como proyecto político de Luigi Ferrajoli (2014)
Authors: España Carreño Andrea
Published: July 2020

«El libro La democracia a través de los derechos del jurista italiano Luigi Ferrajoli explica la relación directa que existe entre la democracia y la garantía de los derechos fundamentales. La democracia expresa la voluntad popular de una sociedad y un método a través del cual se toman decisiones importantes para la solución de problemas que atentan con las emociones y los pensamientos de todos los asociados. El libro es un ejercicio académico que analiza la manera como se lleva a cabo la democracia en el contexto latinoamericano y, en ese orden de ideas, muestra de qué manera los Estados dejan de lado el nexo conceptual que existe entre derechos y democracia. La tesis central reposa en describir la democracia como un hilo conductor a través del cual se asegura la fijación de garantías y de pautas, casi siempre eficientes, que aseguren la mayor esfera de realización de los derechos fundamentales. Afirma Ferrajoli (2014) que la salvaguarda de los derechos fundamentales en general, y los sociales en particular, exige una sobreposición de la política sobre la economía.»
El orden de las cosas: mujeres educadoras y desigualdad de género en la educación superior
Authors: Solís Calvo Ana Magdalena
Published: July 2020

En el presente artículo se retoman algunos principios expuestos por organismos internacionales (Banco Mundial, Unesco, entre otros), que marcan ruta en las actuales políticas públicas en el ámbito educativo con relación a los términos de inclusión y desigualdad en América Latina. La finalidad es revisar las implicaciones del discurso del liberalismo y el capitalismo como principios fundantes de la educación para todos, donde las mujeres son incluidas, pero no tienen las mismas condiciones que los hombres.

Se muestra el caso de dos grupos de estudiantes mujeres de la licenciatura en Educación Preescolar en la Unidad 097 Sur de la Universidad Pedagógica Nacional, en Ciudad de México. Estos casos sirven como referente para cuestionar los elementos imbricados en las políticas educativas actuales y la manera en que las mujeres han ocupado un lugar de desigualdad estructural desde la conformación de la organización de las sociedades, el origen de la democracia y las fusiones patriarcales del capital y los Estados liberales. Al retomar un estudio de caso documentado a través de una investigación cualitativa desde la perspectiva sociocultural y al tener como principal herramienta de indagación las entrevistas a profundidad, las narrativas autobiográficas de las estudiantes dan cuenta de la condición de género y las implicaciones socioculturales, familiares, económicas en las que viven estas mujeres que son a la vez docentes y estudiantes. Los datos empíricos presentados son tamizados por referentes teóricos, entre ellos los feministas, para develar la desigualdad estructural de género vedada bajo las promesas de inclusión educativa en las actuales políticas públicas en el ámbito educativo.
Educación y pobreza: una aproximación documental a los procesos educativos en entornos de exclusión y desigualdad social en Chocó, Colombia
Authors: Chaverra Santos Mirsa
Published: July 2020

La relación entre educación y pobreza es de suma complejidad e involucra múltiples actores, prácticas y discursos de diferente naturaleza y grados de incidencia. Por tanto, la articulación y análisis de las singularidades del contexto social son esenciales en el marco de gestión de cualquier proyecto educativo social tanto para el éxito en el proceso como para el tratamiento y disminución de la pobreza, la exclusión y la desigualdad social. Ante esto, el presente artículo tiene como objetivo general examinar la relación que existe entre educación y pobreza en algunos estudios e investigaciones publicadas durante la última década, dirigidos al análisis de los procesos educativos en el departamento del Chocó a partir de una revisión bibliográfica y documental. El análisis de las fuentes encontradas permitió establecer que la educación centrada en el contexto social (etnoeducación) es fundamental en el tratamiento de la pobreza, cuya incidencia se encuentra determinada por variables y singularidades del contexto mismo que deben ser analizadas e incorporadas en las políticas públicas, contenidos y proyectos educativos, con miras alreconocimiento de la diversidad, la apropiación de las dinámicas del territorio y la vinculación de la población chocoana y de sus particularidades en las dinámicas del sistema educativo.
Kontribusi Zat Gizi Makan Siang Sekolah dan Kecukupan Gizi Terhadap Status Gizi Siswa di SD Al-Furqan Jember
Authors: Ningtyias Farida Wahyu , Fiamanatillah Rahma Fitri , Rohmawati Ninna Rohmawati
Published: July 2020

School lunch facilities may be an alternative to solve food problems in school-age children. The contribution of food nutrients in schools will affect the total consumption of nutrients as well as nutritional status. The contribution of school lunch is 30% of nutritional needs per day. This study was to analyze both the nutritional contribution of school lunch and nutritional adequacy towards the nutritional status of students at Al-Furqan Jember Elementary School. This study was an observational analytic study with a cross-sectional approach. The population was 141 students with total samples of 58 students. This study indicated that most of the respondents did not meet 30% of the daily nutritional needs based on their lunch nutritional contribution. However, both the nutritional adequacy and nutritional status of most respondents were in the normal category.

Abstrak

Fasilitas makan siang sekolah dapat menjadi salah satu alternatif untuk mengatasi masalah makanan anak usia sekolah. Kontribusi zat gizi makanan di sekolah akan berpengaruh pada total konsumsi zat gizi yang juga akan berdampak pada status gizi. Kontribusi makan siang sekolah adalah 30% dari kebutuhan gizi sehari. Penelitian ini bertujuan untuk menganalisis kontribusi zat gizi makan siang sekolah dan kecukupan gizi terhadap status gizi siswa di SD Al-Furqan Jember.Penelitian ini merupakan penelitian analitik observasional dengan menggunakan pendekatan cross sectional. Populasi penelitian ini sebanyak 141 siswa dengan sampel sebanyak 58 siswa. hasil penelitian menunjukkan bahwa sebagian besar responden kontribusi zat gizi makan siang sekolahnya tidak memenuhi 30% kebutuhan gizi sehari. Sedangkan  kecukupan gizi dan status gizi sebagian besar responden dalam kategori normal.
O PAPEL DO TEXTO NA COMPREENSIBILIDADE DE E-SERVIÇOS
Authors: Fischer Heloisa , Mont'Alvão Claudia , Dos Santos Rodrigues Erica
Published: July 2020

Este artigo discute o papel da compreensibilidade textual no acesso a serviços públicos digitais brasileiros, apresentando resultados parciais de pesquisa documental e revisão bibliográfica. O trabalho aborda os conceitos de interação em governo eletrônico, valor público (relacionado ao design do e-serviço), burocratês e Linguagem Simples. Também exemplifica aspectos linguísticos do burocratês a partir de um fragmento de texto de e-serviço do governo federal.
DEFICIENCIES IN THE SUPPLEMENTARY PENSION MARKET IN POLAND FROM THE PERSPECTIVE OF REGULATORY POLICY
Authors: Rutecka-Góra Joanna
Published: July 2020

The supplementary pension market in Poland is regulated to a very limited extent and the range of pension plans available is relatively broad. The regulations in force relate primarily to ensuring financial security from the perspective of the operation of financial institutions, their solvency and liquidity. But efficiency and effectiveness of supplementary pension vehicles in delivering adequate incomes in old age are not regulated or regularly assessed. The most urgent regulatory changes include preliminary product assessment ensuring that only an “appropriate” vehicle is allowed to enter the market, i.e. contracts that meet minimum requirements in terms of design, efficiency and cost. The recommended amendments apply also to risk-sharing, forms of pay-outs, cost limits, market transparency and information policy.
Status Gizi dan Usia Saat Menarche Berkorelasi terhadap Kejadian Dismenore Siswi SMP
Authors: Dewi Ni Putu Sri Ratna , Citrawathi Desak Made , Savitri Ni Putu Wahyunita
Published: July 2020

Tujuan penelitian ini adalah untuk mengetahui: hubungan status gizi dengan kejadian dismenore dan hubungan usia menarche dengan kejadian dismenore pada siswi SMP. Jenis penelitian ini adalah penelitian korelasional dengan responden berjumlah 65 orang yang ditentukan dengan teknik simple random sampling. Uji statistik menggunakan korelasi Product Moment pada taraf signifikansi 5%. Hasil analisis statistik menunjukan untuk hasil hubungan status gizi dengan kejadian dismenore, diperoleh nilai p = 0,008 dengan nilai r = 0,324, dan untuk hasil hubungan usia menarche dengan kejadian dismenore nilai p = 0,005 dengan nilai r = 0,341 serta didapatkan nilai R sebesar 0,430. Dari hasil analisis tersebut dapat disimpulkan bahwa: 1) terdapat hubungan yang signifikan antara status gizi dengan kejadian dismenore, 2) terdapat hubungan yang signifikan antara usia menarche dengan kejadian dismenore dengan tingkat hubungan yang rendah. Status gizi dan usia saat menarche berkontribusi sebesar 43% terhadap kejadian dismenore.
Program Online Scholarship Competition Sebagai Wujud Partisipasi Penciptaan Generasi Emas Indonesia 2045
Authors: Indrati Imam , Islam Muhammad , Paramita Adianti
Published: July 2020

This study aims to evaluate the OSC Program in terms of the mechanism of obtaining scholarships through the online scholarship competition program, and the obstacles faced when screening scholarship candidates. Field observations and interviews are used to collect data, and PESTEL and SWOT techniques are collaborated to identify the strengths, weaknesses, opportunities, and threats. The results show that this program has legitimacy and is officially supported by the Ministry of Research, Technology and Higher Education. Futhermore, OSC has a very clear, segmented and national target market. For private universities and sponsorships that are incorporated can raise the brand image of PTS and scholarship fund companies.
Pembagian Warisan terhadap Anak Perempuan di Mandailing Natal
Authors: Nasution Nindi Aliska
Published: July 2020

This article aims to determine the implementation of property inheritance to daughters in Tanjung Mompang Panyabungan Utara Mandailing Natal and the factors that cause people to choose the way in the distribution of inheritance. This article uses a juridical-empirical approach. The results of this research shows that the distribution of inheritance done traditionally due to the lack of public awareness about Islamic civil law particularly about inheritance. It becomes the most fundamental factors causing disputes and injustice among family members because the inheritance were distributed not in accordance with Islamic law. Religious and education factors are two common factors that determine the distribution of inheritance. Low understanding of Islamic law and inheritance knowledge are the cause of this case.
PENILAIAN ASPEK PENGETAHUAN MELALUI JENIS PENILAIAN TES DI TK AL-FADHILLAH KABUPATEN SLEMAN DIY
Authors: Dilla Raudhah Farah
Published: July 2020

Tujuan dari pendidikan ada tiga yaitu ketercapaian pada aspek sikap, aspek pengetahuan, dan aspek keterampilan. Pengetahuan menjadi salah satu yang sangat penting dikarenakan, sikap positif akan terbentuk dari pengetahuan yang didapatkan dan diekspresikan kedalam bentuk unjuk kerja atau hasil karya peserta didik. Tujuan dari penelitian ini ialah untuk mengetahui bagaimana teknik penilaian tes terhadap aspek pengetahuan yang dilakukan oleh salah satu lembaga Pendidikan Anak Usia Dini di Kabupaten Sleman DIY yaitu di TK Al-Fadhillah. Metode yang digunakan dalam penelitian ini yaitu observasi dengan teknik pengumpulan data dengan wawancara dan dokumentasi dari sumber seorang guru TK Al-Fadhillah. Hasil penelitian didapatkan bahwa penilaian yang dilakukan TK-Alfadhillah dalam aspek pengetahuan menggunakan hasil karya, catatan anek dot, skala lingkup perkembangan, dan percakapan. Pada jenis penilaian tes, tes lisan yang menjadi bentuk penilaian yang paling sering dilakukan dalam mengetahui sejauh mana pengetahuan peserta didik. Tes lisan yang digunakan tidak hanya mendapatkan informasi mengenai aspek pengetahun, akan tetapi juga dapat meningkatkan kemampuan bahasa anak. Hal ini dikarenakan setiap apa yang diungkapkan anak mencerminkan sejauh mana pengetahuan yang dimiliki oleh anak.
EFEKTIVITAS METODE TANYA JAWAB DALAM MENGEMBANGKAN BAHASA ANAK USIA DINI DI RAUDHATUL ATHFAL ISMARIA RAJABASA BANDAR LAMPUNG
Authors: Tamala Epi
Published: July 2020

Bahasa merupakan salah satu aspek kemampuan dasar yang harus dikembangkan pada jenjang pendidikan di Taman Kanak-kanak. Melalui bahasa anak dapat mengenal dan memahami dirinya, sesama, dan lingkungan hidupnya. Namun perkembangan bahasa anak di Raudhatul Athfal Ismaria Rajabasa  Bandar Lampung masih kurang atau belum berkembang dengan baik khususnya pada kelas B6. Maka metode tanya jawab merupakan salah satu metode yang digunakan oleh guru dalam mengembangkan bahasa anak usia dini di Raudhatul Athfal Ismaria Rajabasa  Bandar Lampung. Dengan demikian penulis merumuskan judul penelitian efektivitas metode tanya jawab dalam mengembangkan bahasa anak usia dini di Raudhatul Athfal Ismaria Rajabasa Bandar Lampung.

            Adapun rumusan masalah dalam penelitian ini adalah “bagaimana efektivitas metode tanya jawab dalam mengembangkan bahasa anak usia dini di Raudhatul Athfal Ismaria Rajabasa Bandar Lampung?”. Tujuan penelitian ini adalah untuk mengetahui efektivitas metode tanya jawab dalam mengembangkan bahasa anak usia dini di Raudhatul Athfal Ismaria Rajabasa Bandar Lampung. Dalam penelitian ini penulis menggunakan jenis penelitian deskriptif kualitatif. Teknik pengumpulan data yang penulis gunakan adalah observasi, wawancara, dan dokumentasi.

            Langkah-langkah metode tanya jawab yang telah diterapkan oleh guru dalam mengembangkan bahasa anak usia dini di Raudhatul Athfal Ismaria Rajabasa Bandar Lampung antara lain: Tahap persiapan tanya jawab, tahap awal tanya jawab, tahap pengembangan tanya jawab, tahap akhir tanya jawab. Dengan menerapkan langkah-langkah metode tanya jawab di Raudhatul Athfal Ismaria Rajabasa Bandar Lampung maka perkembangan bahasa anak dapat berkembang dengan baik.

Berdasarkan hasil analisa tersebut, dapat disimpulkan bahwa metode tanya jawab telah dilakukan dengan langkah yang baik dan efektif dalam mengembangkan bahasa anak usia dini.
Potencial alelopático de bioextratos dos resíduos da cana-de-açúcar no controle de bidens pilosa e taraxacum officinale
Authors: Ferreira Nubia Paula , Ferreira Mata Jhansley , Takehiro Fujita Allynson , Martins Heytor Lemos , Fagundes Paula Roberta
Published: July 2020

O trabalho teve como objetivo avaliar o potencial alelopático de resíduos da cana-de-açúcar utilizando bioensaios na germinação de sementes e crescimento de plantas daninhas e plantas bioindicadoras. As doses do bioextratode palha da cana-de-açúcar estimulou o comprimento da parte aérea das plantas daninhas (dente-de-leão epicão-preto) e inibiu o seu percentual de germinação. As doses de palha da cana-de-açúcar podem inibir ou estimular o desenvolvimento das espécies em estudo. As espécies foram inibidas quando pulverizado o pó da palha da cana-de-açúcar em todas as variáveis analisadas. Com os resultados deste estudo, verifica-se a necessidade da continuação deste trabalho, onde poderá ser isolado e identificado o composto fitoquímico de interesse do pó da palha e do bioextrato da palha de cana-de-açúcar, sendo utilizado como controle natural nas fases de germinação e/ou desenvolvimento de plântula ou planta de espécies daninhas (dente-de-leão e picãopreto).