bluuebunny/crossref_metadata_2025 huggingface dataset:
Optical Measurement of Planar Deformations in the Destructive Mechanical Testing of Masonry Specimens
Authors: Lages Martins Luís Filipe , Marques Ana Isabel , Silva Ribeiro Álvaro , Candeias Paulo , Veiga Maria do Rosário , Gomes Ferreira João
Published: January 2020

This paper addresses the planar measurement problem in the destructive mechanical testing of masonry specimens, describing the proposed optical measurement solution. The adopted affine geometrical camera model is described as well as its experimental implementation using a digital camera and a measurement referential traceable to the International System of Units (SI). Experimental results from non-destructive tests are presented and discussed, including measurements obtained from the use of classical contact instrumentation. Measurement estimates and uncertainties related to the quantified mechanical properties are also shown.
Single Image Super-Resolution: Depthwise Separable Convolution Super-Resolution Generative Adversarial Network
Authors: Jiang Zetao , Huang Yongsong , Hu Lirui
Published: January 2020

The super-resolution generative adversarial network (SRGAN) is a seminal work that is capable of generating realistic textures during single image super-resolution. However, the hallucinated details are often accompanied by unpleasant artifacts. To further enhance the visual quality, we propose a deep learning method for single image super-resolution (SR). Our method directly learns an end-to-end mapping between the low/high-resolution images. The method is based on depthwise separable convolution super-resolution generative adversarial network (DSCSRGAN). A new depthwise separable convolution dense block (DSC Dense Block) was designed for the generator network, which improved the ability to represent and extract image features, while greatly reducing the total amount of parameters. For the discriminator network, the batch normalization (BN) layer was discarded, and the problem of artifacts was reduced. A frequency energy similarity loss function was designed to constrain the generator network to generate better super-resolution images. Experiments on several different datasets showed that the peak signal-to-noise ratio (PSNR) was improved by more than 3 dB, structural similarity index (SSIM) was increased by 16%, and the total parameter was reduced to 42.8% compared with the original model. Combining various objective indicators and subjective visual evaluation, the algorithm was shown to generate richer image details, clearer texture, and lower complexity.
Performance Evaluation of Active Noise Control for a Real Device Casing
Authors: Mazur Krzysztof , Wrona Stanislaw , Pawelczyk Marek
Published: January 2020

Reduction of noise generated by devices is an important problem, both in industrial environments where high sound pressure levels may damage hearing, and in households where the sound pressure level is usually moderate, but may cause discomfort and stress. Classically used passive methods often have poor performance for low frequencies. Alternatively, active control can be used to improve noise reduction in this frequency range. In the proposed approach, noise generated by devices may be reduced by controlling vibrations of the casing. The authors previously confirmed the performance of the proposed active control approach using a dedicated noise-canceling casing. Herein, we describe further development and application of the method to an off-the-shelf washing machine. Electrodynamic actuators were installed on four walls of the washing machine. The performance of the control systems was experimentally evaluated during the real spinning phase and the results are reported here.
Assessment of Urban CO2 Measurement and Source Attribution in Munich Based on TDLAS-WMS and Trajectory Analysis
Authors: Lan Lijuan , Ghasemifard Homa , Yuan Ye , Hachinger Stephan , Zhao Xinxu , Bhattacharjee Shrutilipi , Bi Xiao , Bai Yin , Menzel Annette , Chen Jia
Published: January 2020

Anthropogenic carbon dioxide (CO2) emissions mainly come from cities and their surrounding areas. Thus, continuous measuring of CO2 in urban areas is of great significance to studying human CO2 emissions. We developed a compact, precise, and self-calibrated in-situ CO2/H2O sensor based on TDLAS (tunable diode laser absorption spectroscopy), WMS (wavelength modulation spectroscopy), and VCSEL (vertical-cavity surface-emitting laser). Multi-harmonic detection is utilized to improve the precision of both measurements to 0.02 ppm for CO2 and 1.0 ppm for H2O. Using the developed sensor, we measured CO2 concentrations continuously in the city center of Munich, Germany, from February 2018 to January 2019. Urban CO2 concentrations are strongly affected by several factors, including vegetation photosynthesis and respiration (VPR), planetary boundary layer (PBL) height, and anthropogenic activities. In order to further understand the anthropogenic contribution in terms of CO2 sources, the HySPLIT (Hybrid Single-Particle Lagrangian Integrated Trajectory) model was applied to calculate six-hour backward trajectories. We analyzed the winter CO2 with the trajectory clustering, PSCF (potential source contribution function), and CWT (concentration weighted trajectory) methods, and found that local emissions have a great impact on urban CO2 concentration, with main emission sources in the north and southeast directions of the measurement site. In situations with an uneven trajectory distribution, PSCF proves somewhat superior in predicting the potential emission sources compared to CWT.
Towards the Development of an Integrative, Evidence-Based Suite of Indicators for the Prediction of Outcome Following Mild Traumatic Brain Injury: Results from a Pilot Study
Authors: Gozt Aleksandra , Licari Melissa , Halstrom Alison , Milbourn Hannah , Lydiard Stephen , Black Anna , Arendts Glenn , Macdonald Stephen , Song Swithin , MacDonald Ellen , Vlaskovsky Philip , Burrows Sally , Bynevelt Michael , Pestell Carmela , Fatovich Daniel , Fitzgerald Melinda
Published: January 2020

Background: Persisting post-concussion symptoms (PPCS) is a complex, multifaceted condition in which individuals continue to experience the symptoms of mild traumatic brain injury (mTBI; concussion) beyond the timeframe that it typically takes to recover. Currently, there is no way of knowing which individuals may develop this condition. Method: Patients presenting to a hospital emergency department (ED) within 48 h of sustaining a mTBI underwent neuropsychological assessment and demographic, injury-related information and blood samples were collected. Concentrations of blood-based biomarkers neuron specific enolase, neurofilament protein-light, and glial fibrillary acidic protein were assessed, and a subset of patients also underwent diffusion tensor–magnetic resonance imaging; both relative to healthy controls. Individuals were classified as having PPCS if they reported a score of 25 or higher on the Rivermead Postconcussion Symptoms Questionnaire at ~28 days post-injury. Univariate exact logistic regression was performed to identify measures that may be predictive of PPCS. Neuroimaging data were examined for differences in fractional anisotropy (FA) and mean diffusivity in regions of interest. Results: Of n = 36 individuals, three (8.33%) were classified as having PPCS. Increased performance on the Repeatable Battery for the Assessment of Neuropsychological Status Update Total Score (OR = 0.81, 95% CI: 0.61–0.95, p = 0.004), Immediate Memory (OR = 0.79, 95% CI: 0.56–0.94, p = 0.001), and Attention (OR = 0.86, 95% CI: 0.71–0.97, p = 0.007) indices, as well as faster completion of the Trails Making Test B (OR = 1.06, 95% CI: 1.00–1.12, p = 0.032) at ED presentation were associated with a statistically significant decreased odds of an individual being classified as having PPCS. There was no significant association between blood-based biomarkers and PPCS in this small sample, although glial fibrillary acidic protein (GFAP) was significantly increased in individuals with mTBI relative to healthy controls. Furthermore, relative to healthy age and sex-matched controls (n = 8), individuals with mTBI (n = 14) had higher levels of FA within the left inferior frontal occipital fasciculus (t (18.06) = −3.01, p = 0.008). Conclusion: Performance on neuropsychological measures may be useful for predicting PPCS, but further investigation is required to elucidate the utility of this and other potential predictors.
The Effectiveness of Various Types of Psychological Correction of Anxiety in Primary School
Authors: Bartosh Olga P. , Bartosh Tatiana P.
Published: January 2020

At various stages of the development and education of children, there are psychoemotional difficulties that create prerequisites for impairment of the development of the child’s personality. The timely detection of difficulties in schoolchildren and therapeutic efforts are important for the formation of a psychologically healthy personality. The study of the effectiveness of various remedial techniques for childhood anxiety has therefore become theoretically and practically significant. The purpose of our study is to determine the effectiveness of various types of such therapeutic efforts: social and psychological training, a method of biological feedback, and Sandplay for the indicators of childhood anxiety among younger schoolchildren. The study was conducted in the school of Magadan, northeast of Russia (9–10-year-old students, n = 43). We used a standardized method of Multidimensional Assessment of Child Anxiety which included 10 scales. The following therapeutic efforts were used: sociopsychological training (SPT), biofeedback method (BFB), individual and group Sandplay. Students of group I (n = 12) participated only in the SPT. Students of group II (n = 11) participated in the SPT and underwent a course of training in self-regulation using the BFB method. In therapy work with the students of group III (n = 20), the SPT, BFB, individual and group Sandplay were used. In group I, after the therapy sessions, a significant decrease in anxiety was observed in 3 of 10 scales (2, 6, 7; p < 0.05). In group II, it was seen in 5 scales (1, 3, 6, 7, 8; p < 0.05). In group III, significant improvements took place in 7 scales (1, 2, 5, 6, 7, 9, 10; p < 0.01–p < 0.05). The present study has shown the different efficacy of applying the remedial techniques separately and in combination. The use of the therapy methods, in the complex, enhances the impact on the types of child anxiety.
Postnatal Acetaminophen and Potential Risk of Autism Spectrum Disorder among Males
Authors: Bittker Seth S. , Bell Kathleen R.
Published: January 2020

Some evidence from the literature suggests that postnatal acetaminophen exposure may be associated with increased risk of autism spectrum disorder (ASD). Using a data set obtained from a previous study that was derived from an Internet-based survey among parents on 1515 children from the US, an adjusted odds ratio (aOR) and gender-specific aORs for doses of postnatal acetaminophen provided before age two were calculated against the outcome of ASD. Separately, parental uncertainty on the number of doses of acetaminophen provided was analyzed. A population attributable fraction (PAF) associated with postnatal acetaminophen exposure before age two for ASD among males was also estimated. Postnatal acetaminophen exposure, measured in doses before age two, was found to be associated with ASD among male children (aOR 1.023, CI 1.005–1.043, p = 0.020*), and parental uncertainty on the number of doses of acetaminophen provided before age two was also found to be associated with ASD. Using this data set, the PAF associated with postnatal acetaminophen was estimated to be about 40% of the risk of ASD among male children in the US. These results suggest the possibility that postnatal acetaminophen may be a significant contributor to the risk of ASD among males in the US.
Heat Supply Comparison in a Single-Family House with Radiator and Floor Heating Systems
Authors: Vadiee Amir , Dodoo Ambrose , Jalilzadehazhari Elaheh
Published: January 2020

Floor heating and radiators are two of the most common types of hydronic heating systems used for space heating in single-family houses in cold climate regions. Notwithstanding, there are few comparative studies on indoor temperature distribution and system cost evaluations for radiators and floor heating. Furthermore, there are no aligned outcomes in terms of total heat supply for a single-family house with radiators or floor heating. In this study, the effect of building energy efficiency level and construction type, including flooring material, on the supply heating demand and transmission heat losses were studied for both radiator and floor heating systems. For this purpose, a single-family house located in Växjö, Sweden, was modeled as a case study. The heating demand was supplied with a district heating system with a similar supply temperature at 45 °C for both the radiator and floor heating system. A sensitivity analysis was also performed to assess the effect of flooring configurations on the annual supply heating demand for both conventional and passive versions of the case-study building. The results showed that the radiator-integrated building had a lower supply heating demand in comparison with the floor heating-integrated buildings. Based on the sensitivity studies, the flooring material did not have a significant influence on the supply heating demand and on the transmission heat losses in the case of the radiators. The supply heating demand was only reduced up to 3% if the flooring U-value was improved by 60%. The results also showed that refurbishment in a standard conventional building with a radiator heating system based on the passive criteria led to a 58% annual energy savings, while this amount for a building with a floor heating system was approximately 49%.
Fe-Based Metallic Glasses and Dyes in Fenton-Like Processes: Understanding Their Intrinsic Correlation
Authors: Wang Xueqing , Zhang Qiaoyue , Liang Shun-Xing , Jia Zhe , Zhang Wenchang , Wang Weimin , Zhang Lai-Chang
Published: January 2020

Fe-based metallic glasses have been demonstrated as effective heterogeneous catalysts in Fenton-like processes for dye degradation. Yet, currently corresponding studies have limitations due to the limited study object (dyes) and the correlation between metallic glasses and dye pollutants in Fenton-like processes is still not comprehensively studied. Accordingly, this work intensively investigated the thermal catalytic behavior correlations between two Fe-based metallic glasses (Fe78Si9B13 and Fe73.5Si13.5B9Cu1Nb3) and eight different dyes. Results indicated a lower activation energy in the more active metallic glass and a dependence of the activation energy of Fe-based metallic glasses in dye solutions. In addition, a high H2O2 concentration led to a declined catalytic efficiency but a photo-enhanced Fenton-like process overcame this limitation at high concentration of H2O2 due to the decrease of pH and enhancement of irradiation. Furthermore, the average mineralization rates of Fe78Si9B13 and Fe73.5Si13.5B9Cu1Nb3 have been measured to be 42.7% and 12.6%, respectively, and the correlation between decolorization and mineralization revealed that a faster decolorization in a Fenton-like process contributed to a higher mineralization rate. This work provides an intrinsic viewpoint of the correlation between Fe-based metallic glasses and dyes in Fenton-like processes and holds the promise to further promote the industrial value of metallic glasses.
High-Performing Au-Ag Bimetallic Catalysts Supported on Macro-Mesoporous CeO2 for Preferential Oxidation of CO in H2-Rich Gases
Authors: Fiorenza Roberto , Spitaleri Luca , Gulino Antonino , Sciré Salvatore
Published: January 2020

We report here an investigation on the preferential oxidation of carbon monoxide in an H2-rich stream (CO-PROX reaction) over mono and bimetallic Au-Ag samples supported on macro-mesoporous CeO2. The highly porous structure of ceria and the synergistic effect, which occurs between the bimetallic Au-Ag system and the support, led to promising catalytic performance at low temperature (CO2 yield of 88% and CO2 selectivity of 100% at 60 °C), which is suitable for a possible application in the polymer electrolyte membrane fuel cell (PEMFC). The morphological, structural, textural and surface features of the catalysts were determined by Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), N2-adsoprtion-desorption measurements, Temperature Programmed Reduction in hydrogen (H2-TPR), Fourier Transform Infrared Spectroscopy (FTIR) and X-ray Photoelectron Spectroscopy (XPS). Furthermore, the catalytic stability of the best active catalyst, i.e., the AuAg/CeO2 sample, was evaluated also in the presence of water vapor and carbon dioxide in the gas stream. The excellent performances of the bimetallic sample, favored by the peculiar porosity of the macro-mesoporous CeO2, are promising for possible scale-up applications in the H2 purification for PEM fuel cells.
Biochemical and Structural Characterization of Cross-Linked Enzyme Aggregates (CLEAs) of Organic Solvent Tolerant Protease
Authors: Razib Muhammad Syafiq Mohd , Rahman Raja Noor Zaliha Raja Abd , Shariff Fairolniza Mohd , Ali Mohd Shukuri Mohamad
Published: January 2020

Cross-linked enzyme aggregates (CLEAs) is an immobilization technique that can be used to customize enzymes under an optimized condition. Structural analysis on any enzyme treated with a CLEA remains elusive and has been less explored. In the present work, a method for preparing an organic solvent tolerant protease using a CLEA is disclosed and optimized for better biochemical properties, followed by an analysis of the structure of this CLEA-treated protease. The said organic solvent tolerant protease is a metalloprotease known as elastase strain K in which activity of the metalloprotease is measured by a biochemical interaction with azocasein. Results showed that when a glutaraldehyde of 0.02% (v/v) was used under a 2 h treatment, the amount of recovered activity in CLEA-elastase was highest. The recovered activity of CLEA-elastase and CLEA-elastase-SB (which was a CLEA co-aggregated with starch and bovine serum albumin (BSA)) were at an approximate 60% and 80%, respectively. The CLEA immobilization of elastase strain K allowed the stability of the enzyme to be enhanced at high temperature and at a broader pH. Both CLEA-elastase and CLEA-elastase-SB end-products were able to maintain up to 67% enzyme activity at 60 °C and exhibiting an enhanced stability within pH 5–9 with up to 90% recovering activity. By implementing a CLEA on the organic solvent tolerant protease, the characteristics of the organic solvent tolerant were preserved and enhanced with the presence of 25% (v/v) acetonitrile, ethanol, and benzene at 165%, 173%, and 153% relative activity. Structural analysis through SEM and dynamic light scattering (DLS) showed that CLEA-elastase had a random aggregate morphology with an average diameter of 1497 nm.
COUP-TFII in Health and Disease
Authors: Polvani Simone , Pepe Sara , Milani Stefano , Galli Andrea
Published: January 2020

The nuclear receptors (NRs) belong to a vast family of evolutionary conserved proteins acting as ligand-activated transcription factors. Functionally, NRs are essential in embryogenesis and organogenesis and in adulthood they are involved in almost every physiological and pathological process. Our knowledge of NRs action has greatly improved in recent years, demonstrating that both their expression and activity are tightly regulated by a network of signaling pathways, miRNA and reciprocal interactions. The Chicken Ovalbumin Upstream Promoter Transcription Factor II (COUP-TFII, NR2F2) is a NR classified as an orphan due to the lack of a known natural ligand. Although its expression peaks during development, and then decreases considerably, in adult tissues, COUP-TFII is an important regulator of differentiation and it is variably implicated in tissues homeostasis. As such, alterations of its expression or its transcriptional activity have been studied and linked to a spectrum of diseases in organs and tissues of different origins. Indeed, an altered COUP-TFII expression and activity may cause infertility, abnormality in the vascular system and metabolic diseases like diabetes. Moreover, COUP-TFII is actively investigated in cancer research but its role in tumor progression is yet to be fully understood. In this review, we summarize the current understanding of COUP-TFII in healthy and pathological conditions, proposing an updated and critical view of the many functions of this NR.
Coordination and Crosstalk between Autophagosome and Multivesicular Body Pathways in Plant Stress Responses
Authors: Wang Mengxue , Li Xifeng , Luo Shuwei , Fan Baofang , Zhu Cheng , Chen Zhixiang
Published: January 2020

In eukaryotic cells, autophagosomes and multivesicular bodies (MVBs) are two closely related partners in the lysosomal/vacuolar protein degradation system. Autophagosomes are double membrane-bound organelles that transport cytoplasmic components, including proteins and organelles for autophagic degradation in the lysosomes/vacuoles. MVBs are single-membrane organelles in the endocytic pathway that contain intraluminal vesicles whose content is either degraded in the lysosomes/vacuoles or recycled to the cell surface. In plants, both autophagosome and MVB pathways play important roles in plant responses to biotic and abiotic stresses. More recent studies have revealed that autophagosomes and MVBs also act together in plant stress responses in a variety of processes, including deployment of defense-related molecules, regulation of cell death, trafficking and degradation of membrane and soluble constituents, and modulation of plant hormone metabolism and signaling. In this review, we discuss these recent findings on the coordination and crosstalk between autophagosome and MVB pathways that contribute to the complex network of plant stress responses.
Optimization of Antibacterial Properties of “Hybrid” Metal-Sputtered Superhydrophobic Surfaces
Authors: Kefallinou Dionysia , Ellinas Kosmas , Speliotis Thanassis , Stamatakis Kostas , Gogolides Evangelos , Tserepi Angeliki
Published: January 2020

Bacterial attachment and colonization to hygiene sensitive surfaces, both public and nosocomial, as well as in food industry areas, poses a serious problem to human healthcare. Several infection incidents are reported, while bacterial resistance to antibiotics is increasing. Recently, novel techniques for the design of antibacterial surfaces to limit bacterial spreading have emerged, including bifunctional antibacterial surfaces with antifouling and bactericidal action. In this context, we have recently developed smart, universal, metal-sputtered superhydrophobic surfaces, demonstrating both bacterial repulsion and killing efficacy. Herein, we present the optimization process that led to the realization of these “hybrid” antibacterial surfaces. To this end, two bactericidal agents, silver and copper, were tested for their efficiency against Gram-negative bacteria, with copper showing a stronger bactericidal action. In addition, between two low surface energy coatings, the fluorinated-alkyl self-assembled chlorosilane layer from perfluorinated octyltrichlorosilane (pFOTS) solution and the fluorocarbon layer from octafluorocyclobutane (C4F8) plasma were both approved for their anti-adhesive properties after immersion in bacterial solution. However, the latter was found to be more efficient when engrafted with the bactericidal agent in shielding its killing performance. Furthermore, the thickness of the plasma-deposited fluorocarbon layer was optimized, in order to simultaneously retain both the superhydrophobicity of the surface and its long-term bactericidal activity.
Influence of N2 Gas Flow Ratio and Working Pressure on Amorphous Mo–Si–N Coating during Magnetron Sputtering
Authors: Lim Ki Seong , Kim Young Seok , Hong Sung Hwan , Song Gian , Kim Ki Buem
Published: January 2020

In this study, Mo–Si–N coatings were deposited on Si wafers and tungsten carbide substrates using a reactive direct current magnetron sputtering system with a MoSi powder target. The influence of sputtering parameters, such as the N2 gas flow ratio and working pressure, on the microstructure and mechanical properties (hardness (H), elastic modulus (E), and H/E ratio) of the Mo–Si–N coatings was systematically investigated using X-ray diffractometry (XRD), scanning electron microscopy (SEM), nanoindentation, and transmission electron microscopy (TEM). The gas flow rate was a significant parameter for determining the crystallinity and microstructure of the coatings. A Mo2N crystalline coating could be obtained by a high N2 gas flow ratio of more than 35% in the gas mixture, whereas an amorphous coating could be formed by a low N2 gas flow ratio of less than 25%. Furthermore, the working pressure played an important role in controlling the smooth surface and densified structure of the Mo–Si–N coating. For the amorphous Mo–Si–N coating deposited with the lowest working pressure (1 mTorr), the hardness, elastic modulus, and H/E ratio reached from 9.9 GPa, 158.8 GPa, and 0.062 up to 17.9 GPa, 216.1 GPa, and 0.083, respectively.
Ophthalmic Nanosystems with Antioxidants for the Prevention and Treatment of Eye Diseases
Authors: Dinte Elena , Vostinaru Oliviu , Samoila Ovidiu , Sevastre Bogdan , Bodoki Ede
Published: January 2020

Oxidative stress may induce a series of pathophysiological modifications that are directly involved in the development of ophthalmic diseases like age-related cataract, macular degeneration or diabetic retinopathy, considered to be responsible for the majority of vision loss cases. Although various treatment options for eye diseases are available, multiple factors could limit their efficacy. Recently, the accelerated development of ophthalmic nanosystems has provided new possibilities for overcoming the limitations of existing ocular drug delivery methods. This review evaluates the current status of ophthalmic nanosystems loaded with antioxidants for the prevention and treatment of several eye diseases.
Effect of Dew Point and Alloy Composition on Reactive Wetting of Hot Dip Galvanized Medium Manganese Lightweight Steel
Authors: Yang Tong , He Yanlin , Chen Zhang , Zheng Weisen , Wang Hua , Li Lin
Published: January 2020

For its application development, the medium manganese lightweight steel with 3 wt.% and 10 wt.% Mn contents was galvanized in continuous hot dip galvanizing (HDG) simulator and the process parameters on the production line were adopted. Combined with the experimental analysis and thermodynamic calculation, the effect of dew point and alloy composition on the reactive wetting of the steel was investigated. It was shown that MnO existed as a stable oxide for the medium Mn steel with 5 wt.% Al as long as Mn content exceeded 5.1 wt.%. The galvanizability of the steel with 10 wt.% Mn was deteriorated resulting from the formation of a thick and continuous external MnO layer, which had adverse effects on the wettability. MnO particles in the form of unstable phase can be found at the surface of 3Mn steel galvanized at dew point +10 °C. It distributed sparsely and the reactive wettability can be obtained by “bridging connection”, which mitigated the damage of external oxidation. Moreover, the lower dew point, the less tendency to form external oxide. Although the decrease of dew point to −30 °C had a certain benefit for coating quality, the galvanizing quality of 10Mn steel could not be improved due to the formation of a thick MnO layer. Therefore, the Mn content played a stronger role than dew point on the reactive wetting of hot dip galvanized medium manganese lightweight steel.
Microstructure and Sliding Wear Resistance of Plasma Sprayed Al2O3-Cr2O3-TiO2 Ternary Coatings from Blends of Single Oxides
Authors: Grimm Maximilian , Conze Susan , Berger Lutz-Michael , Paczkowski Gerd , Lindner Thomas , Lampke Thomas
Published: January 2020

Al2O3, Cr2O3, and TiO2 are most commonly used oxide materials for thermal spray coating solutions. Each oxide shows unique properties comprising behavior in the spray process, hardness, corrosion, and wear resistance. In order to exploit the different advantages, binary compositions are often used, while ternary compositions are not studied yet. Atmospheric plasma spraying (APS) of ternary compositions in the Al2O3-Cr2O3-TiO2 system was studied using blends of plain powders with different ratios and identical spray parameters. Coatings from the plain oxides were studied for comparison. For these powder blends, different deposition rates were observed. The microstructure, roughness, porosity, hardness, and wear resistance were investigated. The formation of the splats from particles of each oxide occurs separately, without interaction between the particles. The exception are the chromium oxide splats, which contained some amounts of titanium. The predominant oxide present in each blend has a decisive influence on the properties of the coatings. While TiOx causes a low coating porosity, the wear resistance can be increased by adding Cr2O3.
Ultrasound Imaging of the Abdominal Wall and Trunk Muscles in Patients with Achilles Tendinopathy versus Healthy Participants
Authors: Romero-Morales Carlos , Martín-Llantino Pedro , Calvo-Lobo César , San-Antolín Marta , López-López Daniel , Blanco-Morales María , Rodríguez-Sanz David
Published: January 2020

Purpose: To compare and quantify with ultrasound imaging (USI) the inter-recti distance (IRD), rectus abdominis (RA), external oblique (EO), internal oblique (IO), transversus abdominis (TrAb), and multifidus thickness and the RA and multifidus cross-sectional area (CSA) between individuals with and without chronic mid-portion Achilles tendinopathy (AT). Methods: A cross-sectional study. A sample of 143 patients were recruited and divided into two groups: A group comprised of chronic mid-portion AT (n = 71) and B group composed of healthy subjects (n = 72). The IRD, RA, EO, IO, TrAb, and multifidus thickness, as well as RA and multifidus CSA, were measured by USI. Results: USI measurements for the EO (p = 0.001), IO (p = 0.001), TrAb (p = 0.041) and RA (p = 0.001) thickness were decreased as well as IRD (p = 0.001) and multifidus thickness (p = 0.001) and CSA (p = 0.001) were increased for the tendinopathy group with respect the healthy group. Linear regression prediction models (R2 = 0.260 − 0.494; p < 0.05) for the IRD, RA, EO, and IO thickness (R2 = 0.494), as well as multifidus CSA and thickness were determined by weight, height, BMI and AT presence. Conclusions: EO, IO, TrAb, and RA thickness was reduced and IRD, multifidus thickness and CSA were increased in patients with AT.
Cerebral Microbleeds in a Stroke Prevention Clinic
Authors: Cho A-Hyun , Wadi Lara , Chow Daniel , Chang Peter , Floriolli David , Shah Krunal , Paganini-Hill Annlia , Fisher Mark
Published: January 2020

The objective of this study was to assess the effectiveness of a stroke clinic in stroke prevention and progression of cerebral microbleeds (CMB). We conducted a retrospective observational study of patients who visited a stroke clinic between January 2011 and March 2017. Susceptibility-weighted imaging (SWI) MRI studies were obtained at baseline and follow-up visits to identify new infarctions and CMB progression. Patients with CMB who also underwent brain computed tomography (CT) imaging were identified and their cerebral arterial calcification was quantified to evaluate the relationship between the extent of intracranial calcification and CMB burden. A total of 64 stroke patients (mean age 73.1 ± 11.0, 47% males) had CMB on baseline and follow-up MRI studies. During a mean follow-up period of 22.6 months, four strokes occurred (4/64, 6%; 3 ischemic, 1 hemorrhagic), producing mild neurological deficit. Progression of CMB was observed in 54% of patients with two MRIs and was significantly associated with length of follow-up. Subjects with intracranial calcification score > 300 cm3 had higher CMB count than those with scores <300 cm3 at both baseline (12.6 ± 11.7 vs. 4.9 ± 2.2, p = 0.02) and follow-up (14.1 ± 11.8 vs. 5.6 ± 2.4, p = 0.03) MRI evaluations. Patients with CMB had a relatively benign overall clinical course. The association between CMB burden and intracranial calcification warrants further study.
Induced Seismic-Site Effects on the Vulnerability Assessment of a Historical Centre in the Molise Region of Italy: Analysis Method and Real Behaviour Calibration Based on 2002 Earthquake
Authors: Chieffo Nicola , Formisano Antonio
Published: January 2020

The present research aims to estimate the influence of site amplification on the seismic vulnerability of the historical centre of the municipality of Baranello in the Molise Region of Italy. Firstly, a structural and typological characterization of the investigated area has been done according to the EMS-98 scale. Subsequently, the vulnerability assessment of the historical buildings located there has been carried out through an appropriate survey form in order to identify the buildings which are most susceptible to seismic damage. To this purpose, the seismic event occurring in October of 2002 has been selected as a reference earthquake. Moreover, according to the AeDES form implemented by the Italian Civil Protection Department to evaluate the usability of constructions after seismic events, the calibration of the typological vulnerability curves of the built-up area has been done, and a quantitative assessment of the local seismic response has been achieved, based on the seismic motions recorded after the 2002 Molise earthquake. Finally, the local amplification factor, which negatively influences the severity of the seismic damage on the structures, has been taken into account in order to more correctly foresee the expected damage of the inspected urban sector, so as to use more appropriately the achieved results for reliable seismic risk mitigation plans.
Age Associated Decrease of MT-1 Melatonin Receptor in Human Dermal Skin Fibroblasts Impairs Protection Against UV-Induced DNA Damage
Authors: Dong Kelly , Goyarts Earl , Rella Antonella , Pelle Edward , Wong Yung Hou , Pernodet Nadine
Published: January 2020

The human body follows a physiological rhythm in response to the day/night cycle which is synchronized with the circadian rhythm through internal clocks. Most cells in the human body, including skin cells, express autonomous clocks and the genes responsible for running those clocks. Melatonin, a ubiquitous small molecular weight hormone, is critical in regulating the sleep cycle and other functions in the body. Melatonin is present in the skin and, in this study, we showed that it has the ability to dose-dependently stimulate PER1 clock gene expression in normal human dermal fibroblasts and normal human epidermal keratinocytes. Then we further evaluated the role of MT-1 melatonin receptor in mediating melatonin actions on human skin using fibroblasts derived from young and old subjects. Using immunocytochemistry, Western blotting and RT-PCR, we confirmed the expression of MT-1 receptor in human skin fibroblasts and demonstrated a dramatic age-dependent decrease in its level in mature fibroblasts. We used siRNA technology to transiently knockdown MT-1 receptor in fibroblasts. In these MT-1 knockdown cells, UV-dependent oxidative stress (H2O2 production) was enhanced and DNA damage was also increased, suggesting a critical role of MT-1 receptor in protecting skin cells from UV-induced DNA damage. These studies demonstrate that the melatonin pathway plays a pivotal role in skin aging and damage. Moreover, its correlation with skin circadian rhythm may offer new approaches for decelerating skin aging by modulating the expression of melatonin receptors in human skin.
K-Means Clustering-Based Electrical Equipment Identification for Smart Building Application
Authors: Zhang Guiqing , Li Yong , Deng Xiaoping
Published: January 2020

With the development and popular application of Building Internet of Things (BIoT) systems, numerous types of equipment are connected, and a large volume of equipment data is collected. For convenient equipment management, the equipment should be identified and labeled. Traditionally, this process is performed manually, which not only is time consuming but also causes unavoidable omissions. In this paper, we propose a k-means clustering-based electrical equipment identification toward smart building application that can automatically identify the unknown equipment connected to BIoT systems. First, load characteristics are analyzed and electrical features for equipment identification are extracted from the collected data. Second, k-means clustering is used twice to construct the identification model. Preliminary clustering adopts traditional k-means algorithm to the total harmonic current distortion data and separates equipment data into two to three clusters on the basis of their electrical characteristics. Later clustering uses an improved k-means algorithm, which weighs Euclidean distance and uses the elbow method to determine the number of clusters and analyze the results of preliminary clustering. Then, the equipment identification model is constructed by selecting the cluster centroid vector and distance threshold. Finally, identification results are obtained online on the basis of the model outputs by using the newly collected data. Successful applications to BIoT system verify the validity of the proposed identification method.
Pest Management Challenges and Control Practices in Codling Moth: A Review
Authors: Kadoić Balaško Martina , Bažok Renata , Mikac Katarina M. , Lemic Darija , Pajač Živković Ivana
Published: January 2020

The codling moth, Cydia pomonella L., is a serious insect pest in pome fruit production worldwide with a preference for apple. The pest is known for having developed resistance to several chemical groups of insecticides, making its control difficult. The control and management of the codling moth is often hindered by a lack of understanding about its biology and ecology, including aspects of its population genetics. This review summarizes the information about the origin and biology of the codling moth, describes the mechanisms of resistance in this pest, and provides an overview of current research of resistant pest populations and genetic research both in Europe and globally. The main focus of this review is on non-pesticide control measures and anti-resistance strategies which help to reduce the number of chemical pesticides used and their residues on food and the local environment. Regular monitoring for insecticide resistance is essential for proactive management to mitigate potential insecticide resistance. Here we describe techniques for the detection of resistant variants and possibilities for monitoring resistance populations. Also, we present our present work on developing new methods to maintain effective control using appropriate integrated resistance management (IRM) strategies for this economically important perennial pest.
Larger is Better in the Parasitoid Eretmocerus warrae (Hymenoptera: Aphelinidae)
Authors: Wang Tao , Keller Michael A.
Published: January 2020

Eretmocerus warrae (Hymenoptera: Aphelinidae) is a specialist parasitoid that is used for the control of the greenhouse whitefly, Trialeurodes vaporariorum (Hemiptera: Aleyrodidae). We investigated how temperature affects the body-size, life-time oviposition, and longevity of E. warrae at different stages of life. The body-sizes of both this parasitoid and its host are influenced by temperature. Body-volume indices that reflect body-sizes fell by 47.7 % in T. vaporariorum compared with 57.6% in E. warrae when temperature increased from 20 to 32 °C. The life-time oviposition of female adults of E. warrae that grew at the immature developmental temperature of 20 °C was 86 ± 22 eggs, more than 66 ± 11 eggs at 26 °C, and 65 ± 23 eggs at 32 °C. Besides the influence on fecundity, temperature also influences the oviposition behaviour at the adult stage. More eggs were oviposited at 20 and 26 °C than at 32 °C. Higher temperatures reduced survival in the immature developmental stages and longevity in adults. Adult females lived for a maximum of 8.9 ± 1.8 days at 20 °C and laid a maximum of 97.4 ± 23.2 eggs when reared at 20 °C and maintained at 26 °C as adults. Adult body-size is positively correlated with life-time oviposition but not adult longevity. The results imply that temperature influences the nature of interactions between a parasitoid and its host. Larger wasps can live longer and parasitise more hosts, which should improve their performance as biological control agents.
Exercise and Horticultural Programs for Older Adults with Depressive Symptoms and Memory Problems: A Randomized Controlled Trial
Authors: Makizako Hyuma , Tsutsumimoto Kota , Doi Takehiko , Makino Keitaro , Nakakubo Sho , Liu-Ambrose Teresa , Shimada Hiroyuki
Published: January 2020

Depressive symptoms and memory problems are risk factors for dementia. Exercise can reduce these in older people, and horticultural activity can benefit people with dementia. This study assessed the efficacy of exercise and horticultural interventions for community-dwelling older adults with depressive symptoms and mild memory decline. In this randomized controlled trial, older adults (n = 89) were assigned to exercise, horticultural, or control groups. Exercise and horticultural programs included 20 weekly 90-min sessions. The control group attended two 90-min classes. Outcomes were assessed at baseline, and then 6- and 12-months post-intervention. Primary outcome measures were the Geriatric Depression Scale-15 (GDS-15) and Wechsler Memory Scale-Revised. Walking speed, two-minute walking test scores, social network, life space, and subjective daily physical activity were secondary outcome measures. Compared with the control group, the exercise group obtained higher immediate and delayed recall logical memory scores, and the increase in immediate recall scores remained 12-months post-intervention. Two-minute walking performance improved in the exercise group, but not after 12 months. GDS-15 scores showed no significant improvements. The horticultural and control groups showed no differences. Exercise may improve memory, while horticultural activity may not. The effects of exercise and horticultural interventions on depressive symptoms remain unclear.
One Anastomosis Gastric Bypass Reconstitutes the Appropriate Profile of Serum Amino Acids in Patients with Morbid Obesity
Authors: Halinski Lukasz P. , Pakiet Alicja , Jablonska Patrycja , Kaska Lukasz , Proczko-Stepaniak Monika , Slominska Ewa , Sledzinski Tomasz , Mika Adriana
Published: January 2020

Bariatric surgery leads to metabolic benefits in patients with obesity, but their mechanisms are not well understood. The appropriate composition of serum amino acids (AA) is important for sufficient supply of these components into various tissues and organs. Obesity leads to alterations in serum AA concentrations. The aim of this study was to examine the effect of one anastomosis gastric bypass (OAGB), a promising type of bariatric surgery, on serum AA concentrations, which were assayed by LC-MS in serum of 46 bariatric patients prior to and 6–9 months after OAGB, as well as in 30 lean control subjects. The results were analyzed by principle components analysis and metabolic pathway analysis. PCA analysis showed that OAGB led to normalization of serum AA concentrations of patients with obesity to a pattern similar to the control subjects, and the concentrations of essential AA remained decreased after OAGB. Changes of individual AA and their associated metabolic pathways were also presented. OAGB caused normalization of the AA profile, which may contribute to improvement of glucose homeostasis and reduction of cardiovascular risk. Considering decreased essential AA concentrations after OAGB, increased intake of high protein food should be recommended to the patients after this type of bariatric surgery.
Latent Tuberculosis Infection Treatment Completion while Shifting Prescription from Isoniazid-Only to Rifampicin-Containing Regimens: A Two-Decade Experience in Milan, Italy
Authors: Villa Simone , Ferrarese Maurizio , Sotgiu Giovanni , Castellotti Paola Francesca , Saderi Laura , Grecchi Cecilia , Saporiti Matteo , Raviglione Mario , Codecasa Luigi Ruffo
Published: January 2020

To tackle the tuberculosis (TB) epidemic, in 2014 the World Health Organization launched the End TB Strategy, which includes action to prevent latent TB infection (LTBI) reactivation. Available preventive treatments (PT) are based on either isoniazid (INH) alone or rifampicin (RIF)-containing regimens. This study aims to assess and compare PT completion rates, the occurrence of adverse events, and the time of dropout among those receiving INH-alone or RIF-containing regimens at Villa Marelli Institute, Milan, Italy, covering the period from 1992 to 2018. A total of 19,670 subjects, belonging to various risk groups—mainly young (median age of 29 years), foreign-born (73.3%), and males (58.8%)—with presumed LTBI were prescribed PT (79.3% INH-alone and 20.7% RIF-containing regimens). The treatment completion rate was 79.4% on average, with higher rates among those receiving RIF-containing regimens (85.6%) compared to those that were prescribed INH-alone (77.8%) (p < 0.0001). Notably, some of the high-risk groups for progression of LTBI were more likely to complete PT from RIF-containing regimens. These groups included recent TB contact (89.9%, p < 0.0001), healthcare workers (93.5%, p < 0.0001), and homeless people (76.6%, p < 0.0001). Irrespectively of the chosen PT regimen, most of the dropouts occurred between the start of the treatment and the first follow-up visit (14.3%, 15.2% for those on INH-alone vs. 11.1% for those on RIF-containing regimens). Further shortening of the PT regimen is therefore an aim to ensure adherence, even though it might need further efforts to enhance the patient’s attitude towards starting and carrying out PT.
Relationship between Morbidity and Health Behavior in Chronic Diseases
Authors: Lee Munjae , Park Sewon , Lee Kyu-Sung
Published: January 2020

This study aimed to analyze the demographic characteristics and health behaviors related to chronic diseases and to identify factors that may affect chronic diseases. Data from the Seventh Korea National Health and Nutrition Examination Survey were used, and 3795 adults aged above 40 years were included. The following demographic variables were obtained: sex, age, education, income, type of health insurance, and private insurance. The following health behavior factors were also analyzed: medical checkup, drinking, smoking, exercise, obesity, and hypercholesterolemia. Participants with lower socioeconomic status had a higher risk of developing chronic diseases. Meanwhile, those with private health insurance had a lower risk of developing chronic diseases. In addition, participants who underwent medical checkups and performed exercises had a lower risk, while those with obesity and hypercholesterolemia had a higher risk of developing chronic diseases. It is necessary to manage chronic diseases through comprehensive programs, rather than managing these diseases individually, and through community primary care institutions to improve health behaviors.