bluuebunny/crossref_metadata_2025 huggingface dataset:
Первичный амилоидоз с поражением сердца, протекавший под маской гипертрофической кардиомиопатии
Authors: Boldueva S.A. , IArmosh I.V. , SHvec N.S. , Grohotova V.V.
Published: April 2020

В статье рассмотрен случай первичного системного амилоидоза, протекавшего с клинической картиной застойной сердечной недостаточности, рефрактерной к симптоматической терапии. При эхокардиографии у больной длительное время выявлялось утолщение миокарда левого желудочка, что при отсутствии анамнеза артериальной гипертензии было расценено как гипертрофическая кардиомиопатия. Диагноз амилоидоза AL-типа был верифицирован на основании биопсии миокарда с применением гистологического и иммуногистохимического методов. Несмотря на начатую патогенетическую терапию больная умерла в течение 6 мес от ее начала и через 2 года от начала первых симптомов заболевания. Данный клинический случай привлекает внимание врачей к проблеме дифференциальной диагностики гипертрофической кардиомиопатии, ранней диагностике и патогенетическому лечению первичного амилоидоза.
Rencana Strategis Sistem Informasi Untuk Meningkatkan Keunggulan Dengan Ward And Peppard
Authors: Arifin Ismail , Soedijono Bambang , Nasiri Asro
Published: April 2020

Sebagai salah satu klinik penyedia layanan kesehatan, klinik Cahaya kesehatan yang berada di jalan tanggamus, Pinang Raya, Bengkulu Utara melayani rawat inap, berobat jalan, kondisi darurat, apotek serta laboratorium. Dalam hal ini tentunya ada klinik lain yang merupakan pesaing, diantaranya klinik Kencana dan klinik Citra Medika. Untuk bersaing dengan klinik tersebut, klinik Cahaya Kencana terus berusaha meningkatkan keunggulannya agar bisa unggul dari klinik pesaing. Keunggulan kompetitif tidak hanya ada di sektor sumber daya manusia, namun juga dari segi pemanfaatan TI/SI. Agar mendapat keunggulan kompetitif maka klinik Cahaya Kesehatan membutuhkan perencanaan strategis Sistem Informasi yang selaras dengan visi dan misi klinik. Upaya yang dilakukan untuk mencapai keunggulan kompetitif yaitu menggunakan metode Ward and Peppard dan analisis yang digunakan diantaranya analisis SWOT, PEST, Value Chain serta Mcfarlan Strategic Grid. Adapun hasil yang akan diperoleh dari penelitian ini yaitu rekomendasi rencana strategis Sistem Informasi pada klinik Cahaya Kesehatan yang sesuai dengan visi misi dan tujuan klinik. Kata Kunci — Rencana Strategis, Ward and Peppard, Klinik As one of the health service clinics, the Health Light Clinic located on Tanggamus Street, Pinang Raya, North Bengkulu serves inpatient, outpatient, emergency conditions, pharmacies and laboratories. At this clinic, there is another designated clinic, which can be seen at the clinic is the Kencana and Citra Medika clinics. To compete with these clinics, the Cahaya Kencana clinic continues to improve its excellence in order to excel from competitive clinics. Competitive advantages not only in the human resources sector, but also in terms of IT / SI utilization. In order to gain a competitive advantage, the Light Clinic requires an Information System strategic planning that is in line with the clinic's vision and mission. Efforts are made to achieve competitive advantage by using the Ward and Peppard methods to provide analysis that is used by SWOT, PEST, Value Chain and Mcfarlan Strategic Grid analysis. The results to be obtained from this study are the results of the strategic plan of the Information Systems at the Cahaya Kesehatan clinic in accordance with the vision and mission of the clinic. Keywords — Strategic Plan, Ward and Peppard, Clinic
Social Cognitive Theory (SCT) and Students’ Failure in Bachelor of Corporate Administration Programme
Authors: Mohamad Khudzari Juliizaerma , Abdul Halim Syahrina ‘Adliana , Lokman Norziana , Othman Sarina
Published: April 2020

Students' failure is one of the most debatable topics in tertiary education in Malaysia. Failure in certain courses might delay students' progress to graduate-on-time (GOT). This will result in increased cost, time and resources to both the university and student. From an academic perspective, a higher rate of failure will give a negative impression that the course is tough for students to pass. This study aims to investigate the factors contributing to students' failure based on the Social Cognitive Theory (SCT). The students of Bachelor of Corporate Administration (BCA) from the Faculty of Administrative Science and Policy Studies, UiTM were selected to participate in an online survey. SCT has identified three main factors that influence students' failure namely, behavioural, environmental and personal factors. Findings of the study showed that for behavioural factors: students' attendance, total hours spent to study, participation in the classroom, understanding level and students' effort to complete the course are among the reasons that lead to the failure. Additionally, the nature of syllabus, teaching techniques, students learning time and assessment methods are the environmental factors that may lead to failure. Finally, personal factors are represented by individual roles, dispositions and commitment to perform in a particular course. This study concludes that the use of SCT can explain student failures more systematically. The result of the study is able to help the university and lecturer to enhance the teaching and learning approach, revise the assessment method and redesign the programme curriculum. These efforts are deemed pivotal in reducing student failures while maintaining its quality.
i-Sign: Sign Language Learning Application Via Gamification
Authors: Seman Fadhlina Izzah , Mhd Shariff Nor Fahira , Nasaruddin Nor Intan Shafini
Published: April 2020

Hearing loss is a type of disability where people who suffer from it could not hear a sound or can only listen to a sound with certain levels. People with hearing loss use sign language to communicate with others and to help them in their learning process. For this study, an interview and survey were conducted with teachers and students from SK Pendidikan Khas Melaka and few problems have been identified in the learning spectrum of children with hearing disability. They face difficulties in learning due to the lack of exposure about the correct sign language since young, difficulty in interpreting sign language in the conventional teaching material due to the nature of its static image contents, and hearing loss children are also usually less focused in the learning process and are easily distracted by their surroundings when the class is in session. To solve these problems, i-Sign is developed as a learning application that incorporates simple gamification in its development that could help hearing loss children to learn the alphabet and basic words of sign language. The use of gamification and multimedia elements provide a more interactive and fun learning environment for the students instead of using static contents, and are also used to direct students’ attention to the learning activity making them more focused in the learning process. i-Sign was developed using the ADDIE model which includes the Analysis, Design, Development, Implementation, and Evaluation phases. In the evaluation phase, a usability test was conducted on 8 children with hearing loss to test the acceptance of the user towards this application and 91.89% of the respondents found that the application meets their expectation of the application capability in terms of its effectiveness, efficiency and user satisfaction. This shows that gamification can be used as an alternative learning material for hearing loss children and help expose the correct sign language to them.  The application can also be used by the public that wants to learn about sign language.
Aspects of Wellness in a Traditional Leisure Time Game: An Integrated Approach for Teaching Innovation.
Authors: Mohamed Mawarni , Tajuddin Puteri Aquila
Published: April 2020

Malaysia and ASEAN societies are rich with a variety of traditional games and usually played during leisure time. ‘Tossing the Stones’ or Batu Seremban was chosen in this survey. Using a purposive sampling technique, respondents from Malaysia, Philippines, Indonesia and Thailand went through the game intervention and answered the questionnaires provided. The goal was to understand how they perceived wellness while playing this game, after identifying the frequency of Traditional Games engagement. Results showed that Batu Seremban gave high wellness scores such as; M=4.16, SD=.722. The physical, intellectual, social and emotional elements identified in ‘Tossing the Stones’ showed that strong educational elements identified in the traditional leisure game can also be used to teach children and young adults through integration in the curriculum. Suggestions on how the game can be used in classrooms were made based on the findings. 

KEYWORDS: Batu Seremban, Curriculum, Innovation, Leisure, Traditional game, Wellness
INVESTIGATING THE IMPORTANCE LEVEL AND UTILIZATION OF VOCABULARY LEARNING STRATEGIES AMONG TURKISH
Authors: Yolcu Melek , Mirioğlu Meryem
Published: April 2020

This study aims to investigate  (a) the perceptions of 8th grade Turkish EFL learners regarding the importance and use of L2 vocabulary learning strategies (VLS), (b) to find out the relationship between perceived importance level and  application level of VLS and (c) to unearth the most and the least frequently applied VLS by EFL learners in their learning processes. A mixed-method sequential explanatory design was adopted in this study. The quantitative data were collected through a questionnaire based on Schmitt's taxonomy of VLS from 398 participants and analyzed via SPSS; qualitative data were obtained from focus group interviews conducted with 45 volunteer participants and analyzed through thematic analysis. The findings indicated that EFL learners attribute a great level of significance to vocabulary learning. It also revealed that there is a significant relationship between importance and application level of VLS, which demonstrates that the strategies that were given most importance were applied on a larger scale by learners.
 
Keywords: English Language Learning, Vocabulary Learning, Vocabulary Learning Strategies, Learner Perceptions.
NB: Please note that the first author is Melek YOLCU.
Enhancing Reading Comprehension through Metacognitive Reading Strategies and Peer Tutoring among Year 7 Students at a Home School Centre
Authors: Halim Nadiah , Mohd Arif Marina , Supramaniam Kaarthiyainy
Published: April 2020

Many students in Malaysia lack proficiency in the English language, from difficulty understanding the meaning of the text to inferring the text. The use of explicit instruction to introduce reading comprehension skills are also rarely employed in the classroom. This study investigated how metacognitive reading strategies and peer tutoring improved Year 7 students’ reading comprehension at a home-school centre. A total of 20 Year 7 students took part in this research, whereby 10 students were placed in the controlled group and 10 students in the experimental group. Students in the experimental group were exposed to 12 weeks of training on metacognitive reading strategies and peer tutoring session. In addition, IGCSE reading comprehension, learning journals and a semi-structured interview were employed to collect data from the experimental group. A paired sample t-test was conducted to analyse the quantitative data of this study whereas document analysis and thematic analysis were used to analyse the qualitative data. The results obtained from this study indicated that metacognitive reading strategies have assisted students to use suitable techniques to comprehend the reading text and answer the reading comprehension questions. In addition, peer tutoring aids student by having their peers translate meaning of the texts in their native language, explain how to properly use the metacognitive reading skills as well as provide guidance and support in the classroom. Therefore, the findings of this study are significant as it suggests the difficulty of students to adapt to new strategies in a short time; hence, they should be exposed at primary level.

Keywords: Metacognitive reading strategies, peer tutoring, reading comprehension, home- school centres.
Reading Habit and Students’ Attitudes Towards Reading: A Study of Students in the Faculty of Education UiTM Puncak Alam
Authors: Baba Jamiah , Rostam Affendi Faiza
Published: April 2020

Ability to read is crucial as reading affects intellectual and emotional growth of an individual. Those who read well have more chances in widening their mental horizons and better opportunities of success. Hence, this paper is an attempt to understand the reading habits and attitudes of the students in the Faculty of Education in Universiti Teknologi Mara, Puncak Alam. To collect the relevant data, a questionnaire was designed and distributed to 80 students. The questionnaire investigated the students’ reading habit, preferences, and attitudes towards reading. The research findings through quantitative analysis revealed that the students had an overall positive attitude towards academic and leisure reading as they read academically and leisurely daily or at least once a week. Apart from that, digital materials are considered better compared to printed texts when it comes to the students’ preference and its availability. Based on the findings, several recommendations were made to help improve students’ reading habits and attitudes. Having a national survey on Malaysian students’ reading habits is deemed necessary as it can document current trends (including the use of digital materials as a form of reading) and factors affecting students’ reading habits and attitudes so that more fruitful actions to improve students’ reading habits can be taken. Finally, teachers should also play a more significant role in motivating students to read as the findings yield that teachers are shown to have an impact on students’ reading habits and attitudes.

Keywords: reading attitude, reading habit, students’ attitude
METHODOLOGY OF COMPLEX AND INTERDISCIPLINARY RESEARCHES IN MODERN PSYCHOLOGY
Authors: MAZILOV Vladimir A.
Published: April 2020

The article is devoted to the evaluation of perspectives of interdisciplinary researches using in psychological science in modern conditions. There are formulated approaches that let to improve the efficiency of interdisciplinary researches. Although this issue has received considerable attention of researchers, the problem is not solved at the moment. The theory of complex psychological researches as a scientific concept, reflecting the specificity of psychological research has not been developed yet. The reason for this is that researchers try to develop the principles of organization and procedure of this kind of researches. It is possible to develop the methodology and theory of complex psychological researches, based on the understanding of the subject of psychology. It is alleged that at present time the most adequate understanding of the subject of psychology is his interpretation like the subjective world of human.
DIFFERENCES IN USING LMS OR SOCIAL NETWORKS IN EDUCATION
Authors: ASATRYAN Samvel , MARJINYAN Armen
Published: April 2020

In recent years, the use of the learning management system (LMS) in the educator’s practical work is becoming more popular and has many advantages: it allows students to get knowledge faster and deeper, facilitates interaction between students and educators. In addition, the LMS use increases the students’ number in distance education. Academic group in the social network Facebook is used both in the students’ daily life, and is considered as an educational tool. The social network can easily be adapted as an additional learning management system due to the fact that virtual space become a part of our lives and it can be used efficiently to solve much problems “on the spot”. However, the full impact of the academic group in Facebook on learning has not been studied, especially when compared with the use of other training management systems. According to the study results, the Facebook group members surpassed academically those who used Moodle. Moreover, Facebook users held a positive attitude towards learning and interaction, higher motivation to learn compared to Moodle users. This article provides an implementation analysis and possible limitations in the use of the training management system. The study results may be of great interest to educators who suggest taking Facebook as one of the training management systems.
Optyka adaptywna – nowa technologia w diagnostyce obrazowej
Authors: Wasyluk Jaromir , Kaczmarek Ilona , Myślińska Małgorzata , Dubisz Marta
Published: April 2020

Technologia optyki adaptywnej (AO, adaptive optics) stała się w ostatnim czasie cennym narzędziem diagnostycznym w badaniach nad mikrostrukturą i funkcją siatkówki. Wykorzystując światło z zakresu bliskiej podczerwieni, kamera optyki adaptywnej umożliwia nieinwazyjne obrazowanie fotoreceptorów (głównie czopków), ściany i światła naczyń siatkówki, włókien nerwowych oraz struktur blaszki sitowej, które trudno uwidocznić za pomocą innych, stosowanych obecnie technik. Technologia AO może dostarczyć informacji o patologicznych zmianach w siatkówce, nawet gdy brakuje jakichkolwiek odchyleń od normy w obrazowych badaniach strukturalnych lub funkcjonalnych. Obecnie aparat rtx1TM (Imagine Eyes, Francja) jest jedynym urządzeniem z kamerą optyki adaptywnej dopuszczonym do badań okulistycznych w wielu krajach. W niniejszym artykule przedstawiamy krótki przegląd rozwoju technologii optyki adaptywnej oraz stale zmieniające się możliwości jej zastosowania w diagnostyce okulistycznej.
Terapia komórkowa w schorzeniach zwyrodnieniowych siatkówki – nadzieje i zagrożenia
Authors: Machalińska Anna
Published: April 2020

Obecnie brakuje skutecznego leczenia przyczynowego wielu chorób degeneracyjnych siatkówki. Za poprawę morfologii i funkcji degenerującej siatkówki odpowiadają czynniki neurotroficzne wydzielane przez aplikowane komórki, które wykazują dodatkowo wpływ immunomodulujący i redukują odpowiedź zapalną uszkodzonej tkanki. Najlepsze efekty uzyskuje się w początkowym stadium zaawansowania choroby. Pomimo obiecujących wstępnych wyników terapia komórkowa wymaga dalszych badań oceniających jej skuteczność i długoterminowe bezpieczeństwo. Ponadto powinna być prowadzona tylko w ramach bezpłatnych badań klinicznych w certyfikowanych ośrodkach naukowo-badawczych po uzyskaniu świadomej zgody pacjenta na leczenie.
Potencjalne zastosowanie agonistów dopaminergicznych D2 w leczeniu VEGF-zależnych chorób oczu
Authors: Osęka Maciej , Saładziak Katarzyna , Jamrozy-Witkowska Agnieszka , Dziedziak Jacek , Cudnoch-Jędrzejewska Agnieszka , Święch Anna
Published: April 2020

Dopamina oraz agoniści receptorów dopaminergicznych D2 wykazują działanie hamujące aktywność czynnika wzrostu śródbłonka naczyniowego. Działanie to zostało udowodnione w wielu chorobach nowotworowych oraz w zespole hiperstymulacji jajników. Dotychczas przeprowadzone badania wskazują na potencjalne zastosowanie tych substancji również w leczeniu chorób oczu przebiegających ze zwiększonym uwalnianiem czynnika wzrostu śródbłonka naczyniowego, takich jak: wysiękowa postać zwyrodnienia plamki związanego z wiekiem, cukrzycowy obrzęk plamki lub proliferacyjna postać retinopatii cukrzycowej. W niniejszej pracy przedstawiono przegląd najnowszych danych literaturowych na temat potencjalnego zastosowania agonistów dopaminergicznych D2 w leczeniu chorób oczy zależnych od naczyniowo-śródbłonkowego czynnika wzrostu (VEGF).
Chirurgia plastyczna tęczówki. Część 2. Chirurgia z użyciem implantów tęczówkowych oraz techniki łączone. Opisy przypadków
Authors: Cywiński Adam
Published: April 2020

Artykuł opisuje możliwości oraz wskazania do chirurgicznej korekcji ubytków tęczówki z użyciem implantów tęczówkowych oraz ich połączeń z techniką szycia tęczówki na przykładzie pięciu przypadków pacjentów z materiału własnego autora. Wszyscy z nich wyrazili świadomą zgodę na przeprowadzone procedury medyczne. Używając implantów tęczówki częściowych oraz całkowitych, a także sztucznej tęczówki, można skorygować praktycznie wszystkie ubytki oraz niedoskonałości tęczówki. Według autora implanty tęczówki powinny być stosowane w korekcji tych ubytków, których nie można uzupełnić z użyciem technik szycia. W niniejszej pracy przedstawiono pięć przypadków chirurgicznej rekonstrukcji zarówno wrodzonych, jak i nabytych defektów tęczówki.
Leczenie zespołu suchego oka za pomocą kwantowego rezonansu komórkowego
Authors: Fryczkowski Piotr
Published: April 2020

Zrównoważenie składu łez, a co za tym idzie – przywrócenie homeostazy powierzchni oka jest trudne do osiągnięcia. Wpływają na to złożoność składu łez, różnorodność gruczołów wydzielniczych, a także skomplikowane i nie do końca poznane interakcje oddziałujące na skład, jakość i ilość łez. Zastosowanie technologii kwantowego rezonansu komórkowego – Biomolecular Quantum Resonance Rexon EyeTM (Resono Ophthalmic, Włochy) – opiera się na dostarczaniu kwantów (porcji) energii elektromagnetycznej wysokich częstotliwości (4–64 MHz) i niskich mocy, które wchodząc w interakcje z transportem jonów, białek błon komórkowych, a także oddziałując na same komórki, zmieniają ich działanie. Zastosowanie nowej technologii w leczeniu zespołu suchego oka dołącza do istniejących zastosowań kwantowego rezonansu komórkowego, takich jak: chirurgia, leczenie ran, leczenie złamań kości, a także leczenie bólu.
Vulnerabilidades induzidas no Semiárido Brasileiro
Authors: Lemos José de Jesus Sousa
Published: April 2020

O Estudo tem como objetivo aferir os padrões de vulnerabilidades induzidas que acontecem nos 1262 municípios do semiárido brasileiro através de indicadores associados às privações de educação, renda, água encanada, saneamento e coleta sistemática de lixo. A pesquisa também objetivou avaliar como se distribuem os municípios do semiárido brasileiro no que se refere à apropriação do PIB. Os dados utilizados na pesquisa foram coletados junto ao IBGE. Cria-se o índice de vulnerabilidades induzidas que se constitui na média ponderada daqueles indicadores. Na ponderação dos indicadores utiliza-se  o método de análise fatorial com decomposição em componentes principais.  Os resultados mostraram que  os níveis de vulnerabilidades induzidas são elevados nos municípios do semiárido brasileiro e que a grande maioria dos municípios do semiárido tem PIB per capita de no máximo um salário mínimo, e que há heterogeneidade na apropriação do PIB entre esses municípios.
Palavras Chave: Pobreza. Desigualdades. Desenvolvimento. Nordeste.
Effects of transrectal palpation with the fetal membrane slip technique for early pregnancy diagnosis on the proportion and type of associated pregnancy loss in dairy cattle
Authors: Romano Juan E. , Thompson James A. , Kraemer Duane C. , Forrest David W.
Published: April 2020

OBJECTIVE

To assess the effect of transrectal palpation (TRP) performed with the fetal membrane slip (FMS) technique for early pregnancy diagnosis on the proportion and type of associated pregnancy losses (PLs) in dairy cattle.

ANIMALS

580 healthy pregnant cattle.

PROCEDURES

Data for artificially inseminated females with 1 or 2 viable embryos detected by transrectal ultrasonography (TRUS) at approximately 30 days of gestation were retrospectively assessed. Cattle were assigned to 1 of 2 groups on the basis of whether they did or did not undergo TRP once between 34 and 41 days of gestation (palpation and control group, respectively). At approximately 45 and 60 days of gestation, all cattle were reevaluated by TRUS; PL was categorized as type I (FMS detectable by TRP and TRUS-confirmed evidence of embryo or fetus degeneration and a functional corpus luteum) or type II (FMS undetectable by TRP and no TRUS-confirmed evidence of an embryo or fetus or of a functional corpus luteum).

RESULTS

Of the 580 healthy pregnant cattle, 271 underwent TRP and 309 did not. In the palpation and control groups, PL occurred in 40 (14.8%) and 47 (15.2%) cattle, respectively. Among the palpation group's PLs, 17 (43%) were type I and 23 (58%) were type II. Among the control group's PLs, 27 (57%) were type I and 20 (43%) were type II. The prevalance and type of PL did not differ between groups.

CONCLUSIONS AND CLINICAL RELEVANCE

TRP with the FMS technique for early pregnancy diagnosis did not increase the prevalence of PL in dairy cattle or alert the proportion of type I versus type II PL.
Deformations and stability of granular soils: Classical triaxial tests and numerical results from an incremental model
Authors: Sławińska-Budzich Justyna , Mierczyński Jacek
Published: April 2020

This article presents a modified incremental model describing pre-failure deformations of granular soils under classical triaxial conditions. The original shape of equations has been proposed by Sawicki and Świdziński [40, 41]. A new form of equations that are consistent with the proposed definitions of deviatoric loading and unloading is suggested. Triaxial tests necessary for calibrating the proposed model have been performed. The modified model is used to simulate the deformations and stability of sand for every pre-failure loading path and makes it possible to describe the behaviour of granular soil under both drained and undrained conditions.

A comparison of experimental and numerical results is presented. All investigations were performed in a classical tri-axial apparatus.
Analysis of the Collapse Gradient of Deep Water Horizontal Wellbore and the Effects of Mud Chemical Activity and Variation in Water Depth
Authors: Dosunmu Adewale , Nwonodi Roland I. , Ekeinde Evelyn
Published: April 2020

Wellbore collapse is an instability-event that occurs at low mud density and leads to unfavorable economic project, reaching billions of US dollars. Thus, it is important to accurately determine its value, especially in deepwater horizontal wellbores. The main reasons for nontrivial problems with such wellbores are evident: the shale encountered are anisotropic in nature and possess planes of weakness; they react with water-based mud, generate osmotic stresses, swell, and fall unto the wellbore bottom, thereby increasing the non-productive time. To this end, salts are added to reduce the collapse tendency, but it is not currently known what amount of salt addition maintains stability, and does not lead to wellbore fracture; in deepwater, the current trend in global warming means there is a future concern to the industry. As the climate temperature increases, more ice melts from the polar region, the seawater expands and the sea level rises. How to incorporate the corresponding effect on collapse gradient is scarcely known. This study captures the major concerns stated above into wellbore stability analysis. Following the classical approach for geomechanical analysis, Mogi-Coulomb criterion was combined with a constitutive stress equation comprising contributions from mechanical and osmotic potentials of mud and shale. A sophisticated industry model was used to consider the deepwater effect. The results show significant reduction in collapse gradient as the water depth increases, also, larger difference between the mud and shale chemical activities represents higher complexities in the wellbore. In addition, the reduction in the chemical activities of mud limited to 37.5% of the initial value can be practically safe.
Antithrombotic potential of ethanol extract from Gardenia jasminoides leaves planted in Aceh
Authors: VONNA AZIZAH , HIDAYATI NUZUL , SURYAWATI SURYAWATI
Published: April 2020

Therapheutic agents from plants are believed to be effective, sustainable and readily available which stimulate researchers to explore various activities of plants. This study is aimed to investigate the activity of Gardenia jasminoides (G. jasminoidesleaves in enhancing the length of bleeding time and clotting time thus can be optimized to be a potential thrombolytic agent in the future. The animal were classified into 5 groups included 3 treatment groups receiving G. jasminoides leaves (GJL) extract at dose 100, 200, 300 mg/kg BW, 1 positive control receiving aspirin 0.208 mg/20 g  and 1 negative control. Mice treated with GJL extract delayed the clot formation with the highest dose showed effects as strong as positive control.
Opportunities of Humanitarian Engineering in innovation from the base in foodscape, to consolidate peace economies with a territorial focus in Colombia.
Authors: Prada Ana
Published: April 2020

This paper highlights the commitment of the academy to build knowledge in a participatory manner, integrating the actors that are proposed as the object of study. From this perspective, dialogue with the territories is a way of contributing to the construction of peace in Colombia. The notion of Peace Economies is addressed to appreciate the way in which community and associative processes that are created from the territories, starring peasant, indigenous and Afro-Colombian communities contribute to the construction of stable and lasting peace from territorialization, political participation in Territory planning and innovation in foodscapes.

This article seeks to contribute to the reflection on the role that communities can occupy in peacebuilding and the way in which humanitarian engineering can offer solutions to everyday problems of grassroots organizations that seek to innovate from the territories in the food landscapes.
The Protection of the Rights of the Defendant by the Constitutional Court-The Kosovo Case
Authors: Rakaj Adelina
Published: April 2020

The aim of this case study is to analyze the protection of the rights of the defendant in criminal proceedings and the implementation of international standards on the rights of the defendant in criminal proceedings in the domestic law of the Republic of Kosovo. This paper will focus on the role of the Constitutional Court of Kosovo in protecting the rights of the defendant during a criminal process, based on specific cases decided by the Constitutional Court of the Republic of Kosovo. For more than ten years since the Declaration of its Independence, Kosovo has established a legal system, which provides effective protection for the rights of a defendant. A significant role in this regard was played by the fact that Kosovo directly applies the jurisprudence of the International Court on Human Rights (ECtHR), as a constitutional obligation. Out of all institutions of the legal system in Kosovo, which are obliged to protect the rights of defendants, a determinant role was played by the Constitutional Court in such regards, therefore, this paper presents arguments how the Constitutional Court of Kosovo has become a guardian for protection of the rights of defendants, in compliance with the Jurisprudence of the ECtHR
Regulation of enzymatic and non-enzymatic antioxidants contributes to salt tolerance in hitherto unknown upland farmer rice varieties.
Authors: Simon Lins , Akkara Yusuf
Published: April 2020

Salt tolerance potential of the three upland farmer varieties, koduvelliyan, mullankayama and marathondi was evaluated by comparing with the released salt-tolerant pokkali variety, vytilla-2. The salt tolerance exhibited by the upland varieties was identical with the salt tolerant variety. The superoxide (O2-) content in the upland varieties was lower; however, the hydrogen peroxide (H2O2) content increased with the salt concentration. The lesser malondialdehyde (MDA) content in the koduvelliyan variety was equivalent to the vytilla-2 and slight increase was observed in mullankayama and marathondi. The ascorbate (AsA) content in the upland varieties was comparable to vytilla-2 and upon exposure to increased concentration of NaCl, the AsA level reduced in all the treatments. Reduced glutathione (GSH) content was uniform in all the varieties up to a concentration of 100mM NaCl, however, in 125-150mM NaCl, mullankayama showed a pronounced increase in GSH content. Under salt stress, due to the formation of O2-, the oxidation of GSH was higher, maintaining a stable GSH/GSSG ratio. Superoxide dismutase (SOD) and catalase (CAT) activity of the upland varieties was higher than vytilla-2 up to 100mM NaCl, however, in 125-150mM NaCl the SOD activity increased slightly and the CAT activity decreased. Ascorbate peroxidase (APX) activity increased in upland varieties up to 125mM NaCl, and in 150mM NaCl, maintained a steady level in all the varieties. Glutathione reductase (GR) activity increased proportionate with NaCl concentration; with highest activity in all the upland varieties. Monodehydroascorbate reductase (MDHAR) activity was uniform in all the varieties up to 100mM NaCl, however, in 125 and 150mM NaCl, vytilla-2 showed higher MDHAR activity. Dehydroascorbate reductase (DHAR) activity was lesser in upland varieties under salt stress compared to vytilla-2. The GSH/GSSG ratio decreased in marathondi and koduvelliyan varieties with the increase in NaCl concentration, however, in mullankayama and vytilla-2, the GSH/GSSG ratio was higher. The membrane stability index of all the varieties was uniform in all the concentrations of NaCl used, except marathondi. The Na+ content in all the varieties increased in relation to NaCl concentration and the K+ efflux was higher suggesting a higher Na+/K+ ratio, with increased NaCl concentration.
Director of research station of the Academy of Sciences of the Soviet Union Alexander for exploration of the North academician Fersman (based on the materials from the archives of Komi Republic)
Authors: Roshchevskaya Larisa Pavlovna , Roshchevskaya Larisa Pavlovna
Published: April 2020

The object of this research is the scientific and organizational activity of the academician Alexander Fersman on realization of a grand project – the creation of research station of the Academy of Sciences of the Soviet Union for exploration of the North in the deep countryside of the European Northeast of USSR. The source base is presented by the materials from archives, museums and libraries of Komi Republic. The goals of this work consist in characterizing the role of the academician Alexander Fersman in creation of the aforementioned facility based on the documents from regional archives. The integrated approach, principles of scientific objectivity, retrospective method of library studies demonstrate the role of human factors in scientific cognition. Reallocation of institutions of the Academy of Sciences consisted in organization of migration of the collectives with scientific property, formation of the new structure, orientation towards studying defense objectives for ensuring strategic independence of the country and attraction of prominent scholars. Rare publications with autographs prove that the prewar scientific interests in the European Northeast and scientific-propagandistic activity of Fersman during the time of war.
Maps of Minsk of the late XVIII – early XIX century as the sources on social topography of the city
Authors: Biahun Ratsibor
Published: April 2020

This article examines the maps of Minsk of the late XVIII – early XIX century as the sources on social topography of the city. Socio-topographic approach in history implies combining topographic data and social research. City maps have been traditionally viewed as the sources for reconstructing urban topography. However, they often contain valuable data on population of the city, thus it is suggested viewing the maps of Minsk as the carriers of two types of information – topographic and social. Having prepared a review of twenty city maps, the author demonstrates the context of their emergence and provides brief description. The importance of city maps for reconstruction of its topography is underlined. Bases on studying the cartographic content of maps, the author reproduces the image of Minsk of the late XVIII – early XIX; determines the records on social characteristics of urban population. The meaning of cartographic sources for examination of social topography of Minsk is defined.
On the development of methodology of source criticism in the area of philosophy of law
Authors: Gorban Vladimir Sergeevich
Published: April 2020

This article explores the problem of development of methodological framework of source criticism in the area of history of political and legal doctrines (history of philosophy of law). Deficit of the related developments in both, national and foreign legal literature, has a highly negative effect on the quality of selection of the source research material and formulation of valid scientific conclusions that allow conducting historical-philosophical and problematic-theoretical reconstructions of legal and political ideas of the past and modernity in a proper way. The scientific novelty of this work consists in substantiation of scientific importance and possibilities of practical application of such relevant vector of legal methodology as the methodology of source criticism in the area of philosophy of law (history of political and legal doctrines), which is interpreted not only as a set of instrumental cognitive acts, but also as a combination of principles and techniques of ensuring veracity of the content, concept and purpose of legal and political ideas of the past and modernity.
The Effect of Leader Support and Competence to the Organizational Commitments on Employees Performance of Human Resources Development Agency in West Kalimantan
Authors: Waldan Raziki
Published: April 2020

The performance on employees of Human Resources Development Agency in West Kalimantan can be said to be not optimal when viewed from the accuracy of their internal reporting The results of this study can be concluded: 1) there is an influence of leader support on organizational commitment of employees of the Human Resource Development Agency in West Kalimantan. It can be proven empirically that the higher the suitability between the leader's support and its members, it will increase organizational commitment to employees; 2) there is the influence of leaders' support on the performance of employees of the Human Resources Development Agency in West Kalimantan; 3) there is an influence of competence on organizational commitment of employees of the Human Resource Development in West Kalimantan. This is the higher competence of employees, the higher the commitment of employees of the human resource development in West Kalimantan. There is the influence of competence on the performance of employees of the Human Resource Development Agency in West Kalimantan; 4) there is an organizational influence on the performance of employees of the Human Resources Development Agency in West Kalimantan.
Determinants of Shariah Banking Performances in Indonesia Through the Perspective of Economic and Social Level
Authors: Malini Helma
Published: April 2020

Shariah bank has become the core of Indonesia financial industry. In the implementation, Shariah banking in Indonesia is integrated with social issues since the basic fundamental of Shariah banking industry are from religions and regulations. In detail the return are not solely depends on society demand but also related with moral issues. As corruption that kept on happening and political instability makes Shariah Banking industry in Indonesia sensitive and fragile towards socio economic development happening during certain period. This paper attempt to investigate the socio economic factors together with bank specific factors of Indonesia Shariah Banks by using GMM and Quantile regression. The dataset used or in this study involves 34 Shariah banks in Indonesia. In this study, Return on Assets has been found significantly positive to bank specific factors such as credit risk and statistically negative to cost to income ratio. However, it has been found that the relationship between risk and return is heterogenous or dissimilar accross different quantiles. Findings of the study tend to reveal that the socio economic factors particularly corruption, political stability and investment freedom have positive and significant relation to the Shariah bank performances in Indonesia.
Targeting Virus-Host Interaction: An in Silico Approach to Develop Promising Inhibitors Against COVID-19
Authors: Rane Jitendra Subhash , Chatterjee Aroni , Khan Rajni , Kumar Abhijeet , Ray Shashikant
Published: April 2020

The entire human population all over the globe is currently facing appalling conditions due to

the spread of infection from COVID-19 (corona virus disease-2019). In the last few months

enormous amount of studies have been continuously trying to target several potential drug

sites to identify a novel therapeutic target. Spike protein of severe acute respiratory syndrome

coronavirus 2 (SARS-CoV-2) is also being targeted by several scientific groups as a novel

drug target. The spike glycoprotein protein is present on the surface of the virion and binds to

the human angiotensin-converting enzyme-2 (hACE2) membrane receptor thereby promoting

its fusion to the host cell membrane. The binding and internalization of the virus is a crucial

step in the process of infection and hence any molecule that can inhibit this, certainly holds a

significant therapeutic value. We have identified AP-NP (2-(2-amino-5-(naphthalen-2-

yl)pyrimidin-4-yl)phenol) and AP-4-Me-Ph (2-(2-amino-5-(p-tolyl)pyrimidin-4-yl)phenol)

from a group of diaryl pyrimidine derivatives which appear to bind at the interface of

hACE2-SARS-CoV-2S complex (human angiotensin converting enzyme 2 and spike

glycoprotein complex) with a low binding energy (<-8 Kcal/mol). In this in-silico study we

also found that AP-NP interacts with S1 domain of C-terminal part of SARS-CoV-2S

however AP-4-Me-Ph was found to interact with S2 domain of SARS-CoV-2S. The result

suggested that AP-NP and AP-4-Me-Ph have potential to inhibit the interaction between

spike protein and hACE2 receptor also AP-4-Me-Ph might be prevent internalization of the

virion within the host. Further in vitro and in vivo study will strengthen these drug candidates

against the COVID-19.
Water retention characteristics of biopolymer hydrogel containing sandy soils
Authors: Tran Thi Phuong An , Cho Gye-Chun , Ilhan Chang
Published: April 2020

Microbial biopolymers are introduced as a new soil binder which regarded to be environmentally-friendly materials in terms of low carbon emission and low impact on the soil ecosystem. In geotechnical engineering and agriculture, various gel-type materials have been used to improve the water absorbability of sandy soils, and control surface erosion. In this study, the soil-water characteristics of xanthan gum biopolymer-treated sand-clay mixtures are evaluated through a laboratory program using a soil-water characterization apparatus. Sand-clay mixtures are treated with different xanthan gum concentrations as 0% (untreated), 0.1%, 0.25%, 0.5%, 0.75% and 1.0%, to the mass of soil, respectively. Consequently, the xanthan gum-soil water characteristic curve results show the enhanced water holding capacity of soils with higher xanthan gum contents. The presence of xanthan gum hydrogels in the soil increases the initial and residual water contents. Biopolymers retain moisture loss from the soil, which makes the slope of the soil-water reduction curve to be more gradual.
Florence Carala, une figure allégorique de la liberté féminine
Authors: Brassard Christina
Published: April 2020

Ascenseur pour l’échafaud (1958) de Louis Malle met en scène une figure de criminelle chargée de significations. Complice du meurtre de son mari, Florence Carala déjoue les préconceptions genrées de la femme indulgente des années 1950. Par le biais d’une approche inspirée des travaux de Geneviève Sellier, nous interrogeons les manières dont le personnage féminin incarné par Jeanne Moreau perturbe l’ordre patriarcal. En regardant plus spécifiquement la première scène du film ainsi que le verdict final du commissaire de police, nous soutenons l’idée que Florence représente le désir de libération des femmes. Le but est de montré que le film est subversif, car il remet en question la domination masculine.

Mots-clés : Ascenseur pour l’échafaud, Louis Malle, figure, liberté, féminisme, Jeanne Moreau
Rousseur fatale dans La peau blanche de Joël Champetier
Authors: Demeule Fanie
Published: April 2020

L’article s’intéresse à la figure de la femme fatale rousse dans le roman d’horreur québécois La peau blanche (2003) de Joël Champetier. Si les criminelles de Champetier reprennent des traits stéréotypiques liés à la rousseur genrée au féminin, tels que la sexualité perverse et la criminalité, nous observons comment ces personnages offrent aussi un potentiel féministe progressiste, entre autres parce qu’ils constituent un groupe féminin non repentant et victorieux. C’est cette tension entre persistance et subversion de la figure de la femme fatale rousse que nous proposons d’analyser chez Champetier.

Mots-clés : Femme fatale ; figure rousse ; succube ; littérature populaire ; littérature de l’imaginaire ; littérature québécoise ; Joël Champetier ; La peau blanche
Représentations de la mobilité dans le récit de soi contemporain au Canada francophone
Authors: Balint Adina
Published: April 2020

Il existe une relation de complémentarité entre la mobilité culturelle (W. Moser) et la mobilité poétique au sens de la naissance d’un « esprit migrateur », selon Pierre Ouellet. Les deux notions s’appliquent principalement aux contextes de déplacements, de migrations, d’exils et de métamorphoses. En même temps, la notion de mobilité s’inscrit dans le cadre des nouvelles configurations du récit de soi : le récit de la mobilité a pour fonction de cerner de quelle manière un sujet est en mesure de circonscrire une identité propre dans l’espace. En témoigne l’apparition, depuis une vingtaine d’années, de récits de soi littéraires qui mettent l’accent sur le déplacement, et où interviennent des figures de l’hybridité culturelle. À partir de La Ballade d’Ali Baba de l’écrivaine québécoise Catherine Mavrikakis, en dialogue avec L’Énigme du retour de Dany Laferrière, cet article explore la poétique de la mobilité au niveau de la thématique et du discours narratif. Nous mettrons en lumière la capacité des sujets narratifs de se mouvoir dans un espace où les variables de la connaissance et de l’interprétation du monde sont multiples et engagent la rencontre avec l’altérité.

Mots-clés : mobilité, récit de soi, Catherine Mavrikakis, Dany Laferrière, littérature québécoise contemporaine.
Sérotonine ou la quête du bonheur selon Michel Houellebecq
Authors: Amar Ruth
Published: April 2020

Dans cet article je propose d’analyser la quête du bonheur dans Sérotonine, le dernier livre de Michel Houellebecq. Mais dans un premier temps, il sera nécessaire d’explorer les aspects du bonheur tels qu’ils apparaissent dans ses romans précédents. Lecteur boulimique et érudit, Houellebecq convoque dans son œuvre un grand nombre d’auteurs, qu’il cite plus ou moins littéralement. On découvre que deux d’entre eux, à savoir Auguste Comte, le père du positivisme, et Schopenhauer, le maître spirituel de Houellebecq, sont probablement les influences majeures de la conception du bonheur dans l’œuvre. Apparemment ces deux philosophes n’ont rien en commun, toutefois, il est possible de repérer certains points similaires concernant l’idée du bonheur exprimée dans les romans de Houellebecq. Dans son dernier livre Sérotonine, l’intérêt porté au bonheur se précise encore plus, or cette fois, il n’est plus question de philosophie : le titre, scientifique surgit sous la forme d’une hormone : un neurotransmetteur à l'origine de notre humeur, utilisée dans les antidépresseurs pour une meilleure santé mentale. Est-ce à dire que Houellebecq a levé les bras ? Ou bien est-ce au contraire une nouvelle tentative de résistance ? Nous tenterons dans cet article de répondre à la question et voir si la quête du bonheur persiste dans son dernier roman.

Mots clé : quête du bonheur, ère du vide, société, individu, puissances techniciennes, forces intérieures
Claer, José. Mordre jusqu’au sang dans le rouge à lèvres
Authors: Lung Bénédicte
Published: April 2020

Compte rendu, Claer, José. Mordre jusqu’au sang dans le rouge à lèvres