bluuebunny/crossref_metadata_2025 huggingface dataset:
Progressive multifocal leukoencephalopathy, more than an encephalopathy
Authors: David Sáez M , Nadia Valdés R , Cristian Fernández M , Rocío Pacheco E
Published: June 2022

Progressive multifocal leukoencephalopathy is a pathology associated with the presence of the JC virus, although it occurs in other conditions, nowadays most cases occur in patients with AIDS, in severe stages of immunosuppression. This condition, and hence its name, has always been associated with the presence of intracerebral lesions, where it can have a wide distribution. However, it is very rare, if ever, to report lesions of this disease in the spinal cord. We present a case of a 40-year-old patient, an HIV carrier in the AIDS stage, who, in addition to presenting brain lesions, had multiple lesions at the cervical spinal cord level. We believe that these lesions may be more common than believed and should be intentionally sought if possible.
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Authors: not provided erosh
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MELAMPAUI NARASI STIGMATISASI IDENTITAS PEREMPUAN PENGGEMAR: BTS ARMY
Authors: Vasthia Devi Jasmine Floretta
Published: June 2022

Decades have passed but female fans who love male idols are still stigmatized, judged, and reduced to their existence in society and popular culture. This is what also happened to ARMY, fans of the male idol group BTS. Using a literature review elaborated through a feminist perspective, this article will discuss how ARMY is stigmatized not only because of the perceived inferiority of women and the domination of men in society, but also because of their love for male groups including male groups. subordinated within the circle of hegemonic masculinity. However, the gender stigma and stereotype attached to them was successfully broken. ARMY as a female fan group realizes that in essence humans are free creatures who must always make choices in life that will shape them as authentic individuals. With this full awareness, they took action through fan labor and fan activism practices, which in the end led them to optimize their Creative Self.

 

Keywords: ARMY;  fan labor; fan activism; Creative Self; authentic

 

Sudah beberapa dekade berlalu namun perempuan penggemar yang menggemari idola laki-laki masih terstigmatisasi, dihakimi, dan direduksi eksistensinya di tengah masyarakat dan budaya populer. Hal inilah yang juga terjadi pada ARMY, penggemar dari group idola laki-laki BTS. Dengan menggunakan kajian literatur yang dielaborasi melalui perspektif feminis, artikel ini akan membahas bagaimana ARMY distigma bukan hanya karena adanya anggapan inferioritas perempuan dan adanya dominasi laki-laki di dalam masyarakat, namun juga karena kecintaan mereka terhadap group laki-laki yang termasuk kelompok laki-laki tersubordinasi di dalam lingkar hegemoni maskulinitas. Namun stigma dan steriotipe gender yang dilekatkan pada mereka berhasil dipatahkan. ARMY selaku kelompok perempuan penggemar menyadari bahwa pada hakikatnya manusia adalah makhluk yang bebas yang harus selalu memilih pilihan-pilihan dalam hidupnya yang akan membentuknya sebagai individu autentik. Dengan kesadaran penuh ini mereka melakukan aksi melalui praktik fan labor dan fan activism yang mana pada akhirnya menghantarkan mereka pada pengoptimalan Diri Kreatif.

 

Kata kunci: ARMY; fan labor; fan activism; Diri Kreatif; autentik
Strategi Adaptasi Komunitas Sedulur Sikep Desa Klopodhuwur Blora di Era Globalisasi
Authors: Dyani Nurmalya Ayu , Yuhastina Yuhastina Yuhastina , Nurhadi Nurhadi Nurhadi
Published: June 2022

In the era of globalization which was characterized by the advancement of science and technology, caused changes in several aspects of life in the sedulur sikep community in Klopodhuwur village. These changes, also cause various challenges for local confidence convenience such as sedulur sikep communities. Therefore, the purpose of this study is to identify the challenges faced by sedulur sikep communities in the era of globalization and explain the adaptation strategies they do. This study uses qualitative research methods with the presentation of writing is descriptive analysis. The results of this study indicate that the challenges experienced by the Samin Blora community include: 1) the religious education system, 2) government as a change actor, 3) negative stigma from the outside community, and 4) technology development in agriculture. In order to maintain its existence, the Sedulur Sikep Community of Klopodhuwur Village has several forms of adaptation strategies, namely 1) adoption of religious elements, 2) internalization of ajaran Sedulur Sikep, 3) Formation of customary institutions, 4) interactions with outside society, and 5) technology limitations.

 

Di era globalisasi yang ditandai dengan kemajuan ilmu pengetahuan dan teknologi, menyebabkan terjadinya perubahan dalam beberapa aspek kehidupan pada komunitas sedulur sikep Desa Klopodhuwur Blora. Perubahan-perubahan tersebut, juga menyebabkan adanya berbagai tantangan bagi penghayat kepercayaan lokal seperti komunitas sedulur sikep. Oleh sebab itu, tujuan dari penelitian ini adalah untuk mengidentifikasikan tantangan-tantangan yang dihadapi oleh komunitas sedulur sikep di era globalisasi dan menjelaskan strategi adaptasi yang dilakukannya. Penelitian ini mengunakan metode penelitian kualitatif dengan penyajian tulisan bersifat deskriptif analisis.  Hasil penelitian ini menunjukkan bahwa tantangan yang dialami oleh masyarakat samin Blora antara lain : 1) sistem pendidikan agama, 2) pemerintah sebagai aktor perubahan, 3) stigma negatif dari masyarakat luar, dan 4) perkembangan teknologi di bidang pertanian. Agar tetap dapat mempertahankan eksistensinya, komunitas sedulur sikep Desa Klopodhuwur mempunyai beberapa bentuk strategi adaptasi yaitu 1) adopsi unsur agama, 2) internalisasi ajaran sedulur sikep, 3) pembentukan lembaga adat, 4) interaksi dengan masyarakat luar, dan 5) limitasi teknologi.
Социальные медиа в политической коммуникации: руководство по успешной социализации молодежи в политическом пространстве: методическое пособие /
Authors: Киселева Л.С. , Сидорова У.И. , Семёнова А.А. , Киселева О.А. , Николаева М.Э.
Published: June 2022

Методическое пособие в структурированном виде содержит практические рекомендации по использованию социальных медиа в целях формирования политического самосознания молодежи на основе онлайн коммуникации. В пособии систематизированы преимущества использования социальных медиа в сфере политической коммуникации с молодежью, представлены практические советы для работы с некоторыми цифровыми платформами. Пособие будет полезно в работе специалистов федеральных, региональных и местных органов исполнительной власти РФ, занятых в сфере молодежной политики; специалистов в области политического PR, а также всех заинтересованных в расширении политического участия молодежи в жизни страны или региона.
MORAL AND PSYCHOLOGICAL ASPECT OF «HISTORICAL TRAUMA» OF THE ETHNIC GROUP. WHETHER SEPARATISM IS BORN OR RAISED?
Authors:   Vasyl Stefanyk Precarpathian National University, Stetsyuk N. M. , Sheketa M. M. ,   Vasyl Stefanyk Precarpathian National University
Published: June 2022

The purpose of research is to explore and analyze the moral and psychological aspects of separatism, which depends on the individual’s demeanor to the problem of inequality. Each ethnic group has a special history of development, but, unfortunately, its history is not always accompanied only by successful victories. Some ethnic groups have been discriminated for a long period of existence, their culture and language have been disrespected and brutally destroyed. The traumatic legacy of the past has always had a profound imprint on the present and future of every nation. The memory of state’s tragic history, and, especially, the history that is connected with the oppression and intolerance of one ethnic group to another one, has hidden manifestations of separatism in its representatives. The desire to restore «justice» has already spread to many countries around the world and even to the most democratic West countries, that also suffer from separatist movements in their territory. Globalization only accelerates these processes and creates even greater schism in the consciousness of such ethnic groups. Separatist’s political and social position is formed as a result of his upbringing in the same environment, where there is the spirit of revenge for the tragic ancestor’s fate and the restoration of long-awaited «justice» and the retribution for the past mistakes.
Business Decision Making by Big Data Analytics
Authors: Goar Vishal Kumar , Yadav Nagendra Singh
Published: June 2022

Information is the key component towards success when it comes to controlling the decision-makers performance with the quality of a decision. In the modern era, an absolute amount of data is available to organizations for analysis usage. Data is the most important component of the business in the 21st century and a significant number of devices are already equipped with the internet. Based on this the solutions should be studied in order to control and capture the knowledge value pair out of the datasets. Following this, the decision-makers should have access to insightful and valuable data based on the dynamic high volume & velocity using big data analytics. Our research focuses on how to integrate big data analytics into the decision-making process. The B-DAD (big data analytics and decision) framework was created to map the big data tools, its architecture, and analytics for the several decision-making steps by the adoption of methodology based on design science. The ideal goal and offerings of the framework are adopting big data analytics in order to intensify & aid decision making for the organization using an integration of big data analytics into the corresponding decision-making process. Thus, the experiment was carried out in the retail domain to test the framework. As an end result, the results showcased the value-added if big data analytics is integrated with corresponding decision-making activity.
Pyrexia of unknown origin: A microbiological review of cases in pediatric population at a tertiary care hospital
Authors: Bowalekar Sneha S. , Vijaykumar Vijitha
Published: June 2022

: Pyrexia of unknown origin (PUO) was described as a persistent fever above 38.3°C (100°F) that evades diagnosis for at least 3 weeks, including 1 week of investigation in hospital. It may be caused by over numerous infectious, rheumatic/ inflammatory, malignant/neoplastic and miscellaneous disorders.

: Blood specimen of 55 pediatric patients with fever of more than two weeks duration were tested for Typhoid, Rickettsial and Brucella infection serologically. Blood cultures of these patients were tested simultaneously.

: Positivity of Immunochromatographic testing for S. Typhi, Widal slide and tube agglutination test was 20%, 23.6% and 21.8% respectively. Titres of >=1:320 were observed in 4 (33.3%) of widal positive patients against H agglutinins. Positivity in Weil-Felix Tube Agglutination test was observed in 1(1.8%) patient against OX-K antigen, in 8 (14.5%) patients against OX-2 and in 6 (10.9%) against OX-19 antigen. Titre of 1:640 was observed in 1(1.82%) of patients against OX-2. One (1.8%) patient showed positive result in Brucella A/M Tube agglutination test.

: Although serological investigations provide early and presumptive diagnosis of diseases, clinical features and epidemiological factors play an important role for initiation of treatment where facilities for culture and molecular testing are lacking or the results of the same are negative.
Effect of heavy metals on paramecium found in different water bodies of Bhiwandi
Authors: Shaikh Hiba Mohd Shujaat , Pimpliskar Mukesh
Published: June 2022

is a unicellular organism, widely distributed in the freshwater environment, where heavy metals are common contaminants. are very abundant group in aquatic ecosystems, which makes them effective biological indicators of water pollutants. The aim of this study was to determine the ability of to survive in various concentrations of three different heavy metals: Ferrous Sulphate (FeSO), Mercuric Chloride (HgCl) and Zinc Chloride (ZnCl). The ciliates were incubated in solutions with 0.3 to 1.5 ppm of FeSO, 0.01 to 0.05ppm of HgCl and 0.10 to 0.95 ppm of ZnCl. at room temperature. Using compound microscope, microscopic observations of cell divisions rate was conducted after 24, 48, 72 and 120 hours of incubation in the tested solutions and was compared to the control sample. Microscopic observations revealed that all the concentrations of HgCl were lethal for all samples except sample no. 3 while FeSO and ZnCl were found to be growth promoter for of all 10 samples.
Occurrence of Pseudomonas aeruginosa isolated from surgical site infections and wound infections and their antimicrobial susceptibility profile
Authors: Sharma Shweta R , Singh Rinki Kumari , Singh Asok Kr , Farooq Umar , Singh Sudhir , Sharma Vasundhara , Ahamad Imran
Published: June 2022

is a major cause of health care associated infections. It has natural resistance as well as acquired multidrug resistance to various antibiotics leading to increased morbidity and mortality, which lead to problematic condition and increased medical expenses. The main aim of this study was to study the resistance pattern of isolated from samples received from surgical site infections and wound infections.

This study was conducted at Microbiology laboratory of Teerthanker Mahaveer Medical College and Research Centre. Pus and wound swab samples were collected from surgical site infections (SSIs) and wound infections. Samples were cultured on MacConkey and Nutrient agar and incubated at 37°C aerobically. Identification of was done by using conventional method and antibiotic sensitivity was determined with automated Vitek2 compact system.

From January 2021 to November 2021 during this study period, out of 117 positive samples 32 (27.35%) were isolated. The susceptibility pattern showed the organism to be most commonly susceptible to Colistin, Doripenem, followed by Piperacillin/Tazobactam, Imipenem, Amikacin, and was less susceptible to Ciprofloxacin, Ceftazidime.

Presences of multidrug resistance strains have raised significant concern and judicious use of antibiotics is the only option to reduce drug resistance and preventing resistance against reserve antibiotics.
Bacterial isolates & their resistance patterns from blood cultures,KIMS
Authors: Padmaja N , .V Srilalitha , Sree K.Ramya
Published: June 2022

Bloodstream infections (BSI) remain one of the important causes of morbidity and mortality. Microorganisms present in circulating blood result in serious sequelae like shock, DIC, and death. Blood culture is a vital tool for their detection. Drug sensitivity patterns help in rationalizing the treatment. The present study was undertaken to determine the bacterial profile & resistance patterns in our hospital.

To study the bacterial isolates and their resistance patterns from blood cultures.

A retrospective study was conducted from August 2019 to January 2020 in the Dept. of Microbiology, KIMS, Amalapuram. Blood samples were collected from clinically suspected patients with aseptic techniques, processed, isolated and identified according to standard microbiological techniques. Antibiotic sensitivity testing was done according to Kirby-Bauer disk diffusion method.

A total of 57 pathogens were isolated from 380 suspected patients of BSI. Gram-negative bacilli (52.7%) (GNB) were predominant organisms isolated followed by Gram-positive cocci (47.3%) (GPC).(20) and pneumoniae (19) were the predominant pathogens isolated. Among GPC, was highly resistant to Penicillin (85%), Ampicillin (85%), Amoxyclav (75%), and Ciprofloxacin (50%). All Staphylococcal species were sensitive to Methicillin, Vancomycin, Linezolid. Among GNB, exhibited high resistance to Cefixime (95%), Amoxyclav (84%), Ceftazidime (79%). Among 30 GNB, 12(40%) were ESBL producers. Most of the GNB were sensitive to Imipenem.

Appropriate treatment of BSI should be based on the current knowledge of local bacterial resistance patterns of the hospital. Hence this kind of study will help in formulating management guidelines and antibiotic policy
Burden of Klebsiella pneumoniae in late onset neonatal sepsis in a tertiary care hospital in Western Maharashtra
Authors: Karyakarte Rajesh , Sagar Drishti , Pol Sae
Published: June 2022

is a notorious superbug that is rapidly becoming the most common nosocomial pathogen to be isolated from intensive care settings.

: To determine the burden of and associated risk factors of late onset sepsis among neonates admitted into neonatal intensive care unit (NICU).

: A prospective study was conducted among 200 neonates admitted into the NICU of Sassoon General Hospital from January 1, 2019 to December 31, 2019. Neonates <28 days of age exhibiting clinical signs and symptoms of sepsis >72hrs after birth were included in the study. A detailed case history format of patient information was prepared. Blood sample was subjected to identification by culture and real time polymerase chain reaction (RT-PCR). Neonates who were positive by blood culture were confirmed as having sepsis.

: Frequency of was 33.3% by blood culture and 38.1% by RT-PCR. Most of the septic neonates were males (n=6; 60%), formula fed (n=7; 70%), extremely low birth weight (n=6; 60%), delivered through caesarean section (n=6, 60%) and were preterm (n=7; 70%). Mortality was seen in 2 (20%) cases. All the isolates were sensitive to meropenem, piperacillin + tazobactam, amikacin, polymyxin B and colistin.

: Occurrence of was 33.3% in late onset neonatal sepsis by blood culture. Low birth weight, formula feeding, prematurity and caesarean section were associated with a higher risk of sepsis in these patients. Antimicrobial stewardship and hospital infection control measures are need of the hour in preventing late onset neonatal sepsis.
Основные направления дальнейшего процесса информатизации в органах внутренних дел
Authors: Смирнов В.М. , Демкин А.М.
Published: June 2022

В статье раскрываются наиболее важные направления информатизации в ОВД, перспективы и дальнейшие направления этого процесса.
Административные правонарушения, а также преступления в сфере компьютерной информации
Authors: Смирнов В.М. , Ермакова В.А.
Published: June 2022

Компьютерная информация является ценным ресурсом, а поэтому выступает в качестве объекта преступного посягательства. Поэтому законодатель установил административную и уголовную ответственность за совершение преступлений в сфере компьютерной информации.
Наиболее востребованные способы защиты облачных информационных технологий
Authors: Смирнов В.М. , Яценко А.Д.
Published: June 2022

В статье раскрываются наиболее востребованные и надежные способы защиты информации, хранящейся с помощью облачных технологий.
Методы очистки сточных вод на нефтеперерабатывающих заводах
Authors: Багирова Н.Н. , Гусейнова М.А.
Published: June 2022

Рост объемов переработки, модернизация производств с увеличением мощности действующих и строительством новых установок немыслимы без осуществления компенсирующих мероприятий по существенному снижении выбросов загрязняющих веществ в окружающую среду непосредственно н НПЗ. В противном случае выделенные из продуктов нефтепереработки загрязняющие вещества будут выбрасываться в окружающую среду массированно и точечно. Поэтому существует необходимость внедрения таких технологических процессов, которые бы обеспечивали выработку не только экологически чистых топлив, но и снижение выбросов выделенных от технологических установок загрязнений. Кроме того, должны совершенствоваться локальные очистные сооружения, предназначенные для выделения загрязняющих веществ и их утилизации.
Mechanochemical synthesis of polygermanophenylsiloxanes
Authors: Kapustina A.A. , Belozerova L.A. , Libanov V.V. , Kolycheva V.B.
Published: June 2022

One of the promising methods for obtaining metal-containing polyorganosiloxanes is the synthesis by mechanoactivation. The aim of this work is to study the possibility of using the exchange decomposition method for the synthesis of polygermanophenylsiloxanes under conditions of mechanochemical activation.
Preparation of ceramic matrices based on calcium silicate by spark plasma sintering for immobilization of cobalt-60
Authors: Shichalin O.O. , Yarusova S.B. , Papynov E.K. , Gordienko P.S. , Buravlev I.Yu. , Bulanova S.B. , Kornakova Z.E. , Kolycheva V.B.
Published: June 2022

Calcium silicates are a special class of inorganic materials, promising for sorption and immobilization of long-lived radionuclides. A number of domestic and foreign studies pay attention to the sorption properties of amorphous and crystalline calcium silicates nCaO∙mSiO2.
Определение содержания экстрактивных веществ в растительном сырье амаранта тѐмного (A. gypochondriacus)
Authors: Близняк О.В. , Лепѐхина И.Е. , Уранова В.В. , Исякаева Р.Р.
Published: June 2022

Данная статья содержит результаты исследования растительного сырья амаранта темного (A. gypochondriacus) по определению содержания экстрактивных веществ, согласно Государственной фармакопее XIV. В ходе исследования было определено процентное содержание влаги растительного сырья. В работе отражены основные особенности культивирования, заготовки и применения амаранта в современной фармацевтической и косметической отраслях.
Ассоциация качества жизни с длительностью и активностью заболевания у больных с системной красной волчанкой
Authors: Мырзатай М.Е. , Молдатилесова Н.К. , Сыдық П.Ж. , Баймаханова Г.Қ. , Сафиулин Р.А. , Бондарев А.А. , Алина А.Р.
Published: June 2022

Целью данного исследования явилось изучение качества жизни, связанного со здоровьем у больных с системной красной волчанкой (СКВ). В данное исследование включено 30 пациентов с СКВ. По данным опросника LUPUSQOL у пациентов среднего возраста с СКВ выявлены низкие показатели шкал «усталость», «образ тела», «боль». У лиц молодого возраста с СКВ критерии «физическое здоровье», «интимное отношение» в 1,4 и в 2,5 раза были выше, по сравнению с лицами среднего возраста. У больных с СКВ достоверных различий показателей опросника LUPUSQOL в зависимости от длительности заболевания не выявлено. При умеренной и высокой степени активности СКВ и высоком индексе повреждения выявлены более низкие показатели шкал «физическое здоровье», «образ тела», «усталость».
Оценка риска падений у больных с ревматоидным артритом
Authors: Смагулова Г.А. , Алимбетова Г.А. , Гец М.В. , Алина А.Р.
Published: June 2022

Целью данного исследования явилось изучение риска и частоты падений у больных с ревматоидным артритом. В исследование включено 53 пациента с ревматоидным артритом. По результатам исследования выявлен высокий риск падений (81%) у данной категории пациентов. У пациентов с ревматоидным артритом высокий риск падений ассоциирован со степенью активности и с рентгенологической стадией заболевания.
Analysis of Design Solutions for Construction of Hydraulic Engineering Structures in the Development of Placers of Zabaikalye
Authors: Konnov V.I. , Domashina Е.E.
Published: June 2022

Analysis of more than 50 projects of open-pit gold mining and conclusions of the specialists on them allowed us to determine the most optimal variant of design solutions. The article suggests a method of water intake from water bodies for washing gold-bearing sands which helps to maintain sanitary flow of water in the rivers for preservation of aquatic flora and fauna. The following measures have been considered and suggested the most cost-effective and easy solution – an automatic lowering of the water level in the pioneer and working sumps to the design value during the summer rain floods was proposed.
Promising Ways to Recycle and Use Waste from Gas Purification Facilities of Alumina Production
Authors: Shepelev I.I. , Zhukov E.I. , Eskova E.N. , Kiryushin E.V. , Рilyaeva O.V.
Published: June 2022

For the disposal of dust from gas-cleaning facilities of sintering furnaces, in addition to a closed dust circulation scheme, a partial removal of it from electric filters for subsequent use in road construction is proposed. It is shown that dust collected from 4–5 fields of electrofilters containing chlorides and sulfates should be used as additives in a nepheline-crushed stone mixture, which will allow obtaining the required high frost resistance indicators of road mix samples.
Assessment of Small River Watershed Biogenic Washout and Reducing Measures
Authors: Kireycheva L.V. , Yashin V.M. , Timoshin A.D.
Published: June 2022

The pollutants input into the Yakhroma River, a tertiary branch of the Volga tributary, was assessed. The quality of thalweg water was studied, as a result of which biogenic pollution was revealed by insufficiently treated wastewater from cities and arable land. Calculation of biogenic pollutants inputs into the river on the basis of GIS of the selected zones of watershed by washout intensity depending on slope angles and types of soils, was performed. Protection measures to reduce diffuse pollution of the river were proposed.
Technogenic Pollution of Soils with Heavy Metals and their Accumulation in Leaves and Needles of Forest-forming Species of the Cis-Urals
Authors: Urazgildin R.V. , Suleymanov R.R. , Giniyatullin R.Kh. , Tagirova O.V. , Kulagin A.Yu.
Published: June 2022

Forest-forming species of the Cis-Urals (pine, spruce, larch, oak, linden, birch) and soils in forest stands of these species were chosen as study objects. The content of heavy metals (HM) in leaves and needles of forest-forming species, as well as in soils, was analyzed. Different concentrations of HMs were revealed depending on the soil layer. It was shown that adaptations to HM pollution do not depend on whether trees belong to coniferous or deciduous species, which indicates different adaptive potentials of species in each specific case.
The Study of Blood Biomarkers in the Pathogenesis of Fibromyalgia: A Case-Control Study
Authors: Salesi Mansour , Hosseinpoor Sara
Published: June 2022

Fibromyalgia (FM) is a chronic musculoskeletal syndrome characterized by pain and fatigue; however, its etiology remains unknown, and various hypotheses and biomarkers have been proposed. This study it is aimed to investigate blood biomarkers in the pathogenesis of FM. The current case-control study has been conducted on 45 females with the documented diagnosis of FM and 45 healthy controls referring to the outpatient clinic of rheumatology in 2018-19. The serum levels of dehydroepiandrosterone (DHEAS), erythrocytic sedimentation rate (ESR), C-reactive protein (CRP), complete blood count (CBC), and thyroid-stimulating hormone (TSH) was measured and compared between the groups. DHEAS serum levels in cases and controls were 27.55±18.80 and 33.55±21.80, (P=0.16), ESR was 29.17±9.75 and 17.37±2.82 (P<0.001), CRP was 4.17±1.53 and 3.53±1.15 (P=0.02), TSH was 3.307±0.27 and 3.41±0.22 (P=0.09), respectively. The two groups were similar in CBC indices, including hemoglobin, hematocrit, white blood cell, lymphocyte, neutrophil, and platelet count (P>0.05). DHEAS was slightly, but insignificantly, lower among the females with FM than healthy cases. On the other hand, the serum ESR and CRP levels were remarkably higher among the females with FM; however, in the normal range, a fact representing the possible traces of inflammation in the pathogenesis of FM.
Influence of Vitamin D Status on Fatigue in Ankylosing Spondylitis
Authors: Tekaya Rawdha , Hamdi Ons , Jemmali Ines , Tekaya Aicha Ben , Rouached Leila , Saidane Olfa , Bouden Selma , Bouzid Kahena , Mahmoud Ines , Abdelmoula Leila
Published: June 2022

Fatigue is a common symptom in ankylosing spondylitis. Hypovitaminosis D is one of the factors influencing fatigue during inflammatory rheumatisms. This study aimed to determine the influence of vitamin D deficiency on fatigue in ankylosing spondylitis. In this cross-sectional study, 40 patients with ankylosing spondylitis and 40 patients suffering from low back pain were recruited. Clinical and laboratory data, including vitamin D dosage, disease activity, functional impairment, and quality of life, were evaluated using specific and validated scores. Fatigue was assessed by the FACIT-F score. Both groups of patients were compound of 27 men and 13 women with a mean of 43.55±12.26 years in the study group and 47.77±13.63 years in the case group, respectively. Ankylosing spondylitis was active according to the ASDASCRP score in 67.5% of cases. All patients were suffering from fatigue with a mean FACIT-F score of 21.13. Severe levels of fatigue were noted in 50% of cases. 92.5% of patients were vitamin D deficient with a mean vitamin D of 16.57±7.15 ng/mL. Factors associated with fatigue were: female gender (P=0.05), spinal pain (P<0.001), enthesitis (P<0.001), disease activity (P<0.001), functional impairment (P<0.001), and quality of life (P<0.001). However, smoking was the only factor related to vitamin D deficiency (P=0.05). Vitamin D level was not correlated with fatigue (r= -0.02, P=0.91). In our study, vitamin D status did not seem to have an impact on fatigue in patients with ankylosing spondylitis.
UPAR Overexpression Could Be a Potential Favorable Prognostic Marker in Invasive Ductal Carcinoma of Breast
Authors: Abbasi Ata , Mehdipour Elnaz , Mojdeganlou Hengameh
Published: June 2022

Breast cancer is the most common malignant tumor in women. Some factors, including histological grade, vascular invasion, and metastasis, are known prognostic factors. Many studies have been performed to find more predictive factors such as urokinase plasminogen activator system markers. Here, we tried to evaluate the relationship between Urokinase-type plasminogen activator receptor expression and other histopathologic parameters. 62 malignant breast tumors were enrolled. UPAR immunohistochemistry staining was performed on paraffin blocks. We evaluated the relationship between UPAR expression and histopathologic factors, including tumor size, tumor type, histologic grade, lymph node status, lymphovascular and perineural invasions, and hormone receptors status (ER, PR, and HER2). The patient's mean age was 46.18±10.35 years. We found a positive relationship between UPAR expression and the presence of carcinoma insitu (P=0.027). A negative relationship was observed between UPAR expression and lymph node involvement (P=0.01), the number of involved lymph nodes (P=0.027), and also intensity and percentage of UPAR positivity in the case with lymph node involvement (P=0.005 and 0.029, respectively). UPAR expression is associated with lymph node metastasis which is one of the most important predictors of prognosis in breast cancer. So, it could be used as a favorable prognostic factor in breast cancer.
Pulmonary Function Test in Rheumatoid Arthritis Patients
Authors: Mehrabi Samrad , Ebrahimi Bahareh , Heydari Fatemeh , Nazarinia Mohammad Ali
Published: June 2022

Lung disease is a common and important contributor to morbidity and mortality in rheumatoid arthritis (RA) patients. Studies have shown that diagnostic methods can reveal hidden pulmonary diseases even in RA patients with no respiratory symptoms. In this study, we assessed pulmonary function tests (PFTs) and chest radiographs (CXRs) in RA patients with more than three years of illness to find a suitable instrument for prospecting RA-induced lung diseases. We conducted a prospective cross-sectional study on 57 RA patients. Demographic, clinical, and CXR data were recorded. Residual volume (RV), total lung capacity (TLC), forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), and FEV1/FVC ratio was assessed. According to the FEV1/FVC ratio, patients were divided into three groups: FEV1/FVC below 70% (obstructive pattern) in 5% and between 70% and 85% (normal) in 50%, and above 85% (restrictive lung disease) in 45% of RA patients. Normal X-ray was the most common finding in CXR, and only cystic changes and reticular changes were found in 5% of patients. Analysis showed a significant relationship between abnormal chest images and the duration of disease (P=0.025), but PFT data did not result in any significance. Respiratory symptoms or clinical examinations are positive findings in the evaluation of asymptomatic patients, and using PFT is more rational than CXR. Our data show that there is no correlation between the disease duration and PFT data; hence, asymptomatic patients with a variety of risk factors should undergo further investigation.
Primary Squamous Cell Carcinoma of Prostate With Direct Extension to Bladder
Authors: Tahbaz Sahel Valadan , Yahyazadeh Hossein , Molanaei Saadat , Beheshti Marziyeh
Published: June 2022

SCC of the prostate is different from other adenocarcinomas in its treatment and prognosis. Here, the patient is a 57-year-old man with benign prostatic hyperplasia that underwent a prostatectomy and, after one month with hematuria and another follow-up radical cystoprostatectomy with lymphadenectomy and urethrectomy. After recovery, the patient experienced radiotherapy and chemotherapy sessions. So, from a review of other literature, we present our case report of squamous cell carcinoma of the prostate that is more aggressive than adenocarcinoma.
Finanse łańcucha dostaw w obliczu wyzwań współczesnej logistyki
Authors: Pawlicka Kinga , Bal Monika
Published: June 2022

The cognitive goal of the article is to systematize the knowledge of supply chain finance (SCF) management in the context of contemporary trends and challenges in logistics. According to the authors, there is a need to draw attention to and organize knowledge in the field of combining supply chain finance with modern solutions such as blockchain technology or sustainable finance. As a part of the implementation of the goal, it was necessary to critically evaluate the current literature on SCF and current trends affecting the development of the SCF concept, as well as to formulate the potential effects of SCF management in the enterprise. Summarizing the considerations, the authors indicate the direction of further research.
Rozwój rynku e-commerce w Polsce – wybrane zagadnienia
Authors: Majchrzak-Lepczyk Justyna
Published: June 2022

Electronic commerce is a very dynamically developing distribution channel, which in recent years has turned from an additional way of selling products into a major source of sales and reaching customers. Undoubtedly, e-commerce offers many solutions that respond to the diverse needs of consumers. In addition to providing a wide range and full availability of products, issues related to logistics services, especially the implementation of deliveries, are also important. For several years, e-commerce in Poland has been recording clear increases. An increasing number of customers are expressing interest in e-shopping. The purpose of the article is to indicate the role of the growing importance of e-commerce in Poland and the demand it determines for warehouse space and their equipment. The formulated conclusions were supported by the author’s own observations, as well as a literature review and current reports and market analyzes were used.
Transformacja łańcucha dostaw. Studium przypadku przejęcia ukraińskiego oddziału globalnej firmy produkcyjnej
Authors: Sadowski Adam , Gresik Tomasz
Published: June 2022

Supply chain management is subject to transformations that result from both functional and structural changes. The greatest challenges for maintaining the efficiency of the supply chain processes are mergers and acquisitions, which require deep interference in the structure of the supply chain. In the case of global supply chains, it is worth mentioning that the cultural aspects influence transformation and their pace of introduction. In this chapter we presented the process of taking over the Ukrainian branch of the global production company DEF (a fictitious name) and including it in the management structures of Central Europe (CE).
Transport publiczny w miastach z perspektywy pandemii COVID-19
Authors: Jurczak Marcin
Published: June 2022

There is no doubt that the global pandemic has affected all areas of the economy. Public transport in cities, as a derivative of the transport needs of residents, felt these changes very strongly. The purpose of this article is to present selected issues related to changes in public transport as a result of the COVID-19 pandemic. Changes which, although for today are primarily operational, may forever change the way people think about public transport. Today, experts are trying to outdo each other in catastrophic visions regarding further pandemic attacks or other viruses that may affect the economy in the coming years. Following this pessimistic trail, it can be assumed that the next months and years will be marked by the stabilization of public transport in the new circumstances and reorganization after the changes. The changes that have come, are coming and may come anytime soon. The author makes a few basic hypotheses. Firstly, that COVID-19 will force a remodelling of the organization of public transport, and these changes will be systemic in nature. Secondly, these changes will concern the first stage of transport organization. At a later stage, it can be expected that the changes will also apply to the financing of transport and planning it at the strategic level (after the stage of dynamic changes and stabilization, in the long term, it will be necessary to consider what to do next, in the context of financing transport, efficiency, etc.). It should also be considered whether, from the point of view of public transport, the coronavirus can be used as an opportunity for the development of selected areas of transport, primarily in the context of the reorganization of transport and the digitization of their administrative services. The impact of the coronavirus on public transport is a relatively new area of research, and A. Koehl (2020) and A. Ceder (2020) are writing about the challenges and the future of transport in the times of COVID-19.
Propuesta para la optimización de portafolios de los fondos de pensiones
Authors: Bernal Sandoval Eliana Paola
Published: June 2022

La apertura del mercado de capitales colombiano ha permitido incrementar el régimen de inversiones de los Fondos de Pensiones Obligatorias (FPO) y, por lo tanto, da más responsabilidad a los administradores de los fondos al gestionar de manera eficiente los recursos de los cotizantes. Debido a la creación de nuevos instrumentos de inversión, la Superintendencia Financiera de Colombia (SFC), en su calidad de ente regulatorio, ha determinado el universo de activos admisibles de dichos portafolios y ha impuesto límites de inversión a ciertos instrumentos, emisores y emisiones. Respecto al proceso de optimización de los portafolios de los FPO, los estudios han utilizado la metodología clásica de media-varianza y algunas alternativas como el criterio retorno total-máximo drawdown. En razón de lo anterior, es importante seguir evaluando la eficiencia de los portafolios teniendo en cuenta nuevos enfoques alternativos a fin de establecer la mejor estrategia estructural para este tipo de portafolios, cuyo objetivo es asegurar el ingreso al momento del retiro de los afiliados del sistema general de pensiones. Este documento considera el método Most Diversified Portfolio (MDP) para la selección de activos dentro de un portafolio de pensiones, como una guía para el establecimiento de la estrategia de inversión de las Administradoras de Fondos de Pensiones (AFP), basado en el concepto de diversificación y explorando un enfoque alternativo a la teoría clásica de media-varianza.
Valoración de derivados bajo un modelo de difusión con saltos del subyacente en mercados con liquidez estocástica
Authors: Moreno Trujillo John Freddy
Published: June 2022

Una de las fallas del modelo Black-Scholes de valoración es asumir que las actividades de negociación de los agentes no tienen efecto sobre los precios, supuesto que solo puede cumplirse en mercados perfectamente líquidos, lo que hace que el modelo sea muy restrictivo. Este elemento ya ha sido considerado en algunos trabajos que incorporan el efecto de las actividades de negociación de los agentes asumiendo un proceso continuo para la dinámica de los precios, sin embargo, los mercados financieros muestran que una mejor descripción de la dinámica de los precios de activos riesgosos debe incorporar saltos aleatorios. La contribución de este documento es considerar el problema de la valoración de derivados en mercados ilíquidos en donde el precio del activo subyacente sigue un proceso de difusión con saltos. Se presenta la ecuación diferencial parcial no lineal de valoración correspondiente y se describe la estrategia de negociación que minimiza la varianza de la cobertura.
Visão de empreendedorismo e atitudes inovadoras na gestão pública e nas Organizações Sociais de Saúde
Authors: Pereira Péricles Ewaldo Jader , Schneider Lucas , Fávero Jeferson Deleon
Published: June 2022

Esse artigo busca verificar como o perfil empreendedor e atitudes inovadoras são vistos na gestão pública e nas organizações sociais de saúde segundo o olhar de seus gestores. A pesquisa é descritiva, com abordagem qualitativa e o uso do método de estudo de caso. As informações foram coletadas por meio de dados secundários e entrevistas semiestruturadas, com gestor público e gestor de uma organização social de saúde. As entrevistas contemplaram conceitos da literatura de empreendedorismo, gestão pública e de organizações sociais de saúde. A pesquisa identificou que o perfil empreendedor é visto por seus gestores como fundamental tanto para a gestão pública, por causa da escassez e burocratização dos recursos públicos como de organizações sociais de saúde, pelas regras de cumprimento dos contratos firmados com o poder público na gestão de unidades de saúde municipais. Em maior ou menor escala, as organizações sociais de saúde apresentaram os traços de empreendedorismo e inovação, sendo que, dependendo da finalidade da constituição e da configuração que a organização social apresenta, alguns elementos sobressaem sobre os outros em grau de importância.