bluuebunny/crossref_metadata_2025 huggingface dataset:
Una periodización de la presencia de Proust en la novela brasileña: Jorge de Lima, Augusto Meyer y Pedro Nava
Authors: Mauro Fillipe
Published: August 2021

La obra de Proust llegó a Brasil durante la década de 1920 y rápidamente se convirtió en uno de los temas favoritos de críticos y escritores del país. Los artículos se multiplicaron en periódicos y revistas; los poetas escribieron odas y elegías a Proust; en poco tiempo, la élite de la literatura brasileña moderna se unió en un esfuerzo por publicar la primera traducción de la Recherche en portugués. Sin embargo, una faceta de la importante circulación de Proust en Brasil permanece aún poco estudiada. Diferentes novelas incorporaron algunos rasgos importantes de la estética proustiana para expresar las más variadas visiones sobre la transformación del tiempo y de la vida en Brasil. Este artículo presentará tres casos muy representativos de este fenómeno de “reparto de una situación objetiva”, como diría Fredric Jameson, en el que “todo un grupo de respuestas variadas e innovaciones creativas es posible”: el tiempo perdido católico en A Mulher obscura, de Jorge de Lima (1939); el tiempo perdido regionalista en Segredos da infância, de Augusto Meyer (1949); y el tiempo perdido psicológico en Baú de ossos, de Pedro Nava (1972).
Entre el cielo y el infierno: travesía de una flâneuse. Nada, de Carmen Laforet
Authors: Tanner Constanza
Published: August 2021

En la primera novela publicada por la escritora catalana Carmen Laforet, Nada, de 1944, la ciudad de Barcelona trasciende la función de mero escenario para la acción y se transforma en condición indispensable para que la protagonista, Andrea, descubra y reinvente su rol dentro de la sociedad. La experiencia urbana de Andrea será un viaje iniciático que la enfrente con dos imágenes de Barcelona en apariencia contradictorias: una Barcelona idílico-apolínea y una Barcelona grotesco-dionisíaca. De forma paralela a su crecimiento como mujer, Andrea aceptará para sí el rol de flâneuse, y desde allí descubrirá una tercera cara de Barcelona, la ciudad moderna, que le mostrará en qué medida las otras dos pueden ser complementarias. En su búsqueda, Andrea descubrirá que su lugar no puede acordar con los recorridos que la tradición y el conservadurismo de la España de posguerra le permiten seguir a una mujer, ni limitarse a los espacios que figurarían en un esquema de Barcelona pensado para turistas. Andrea solo podrá hallarse en la ciudad íntima, autobiográfica, que descubrirá por sí misma como flâneuse, libre de imaginarios impuestos.
La violencia positiva y el imperativo neoliberal de rendimiento en La habitación oscura, de Isaac Rosa
Authors: Prada Laura Mercedes
Published: August 2021

La habitación oscura (2013) de Isaac Rosa advierte, a través de técnicas discursivas como las analepsis y las prolepsis, enumeraciones ascendentes, préstamos de técnicas cinematográficas, entre otras, que la libertad prometida por el sistema neoliberal es una ilusión que tiene como objetivo crear en el individuo la idea de independencia laboral cuando en realidad inocula en él la necesidad de producir constantemente, cumplir con las exigencias autoimpuestas y, de este modo, mantener su estatus o ascender a otro. La autoexplotación de los protagonistas de la novela es una de las representaciones de la violencia positiva, la cual es imperceptible y, por ello, más nociva y peligrosa debido a que los sujetos no se percatan del daño autoinflingido hasta que es demasiado tarde. En este sentido, el cuarto oscuro que un grupo de amigos comparten durante quince años se transforma en el espacio para alejarse del vértigo, el bullicio y las obligaciones que trasfiguran a la persona en prisionera de sus propios mandatos y las demandas implícitas del sistema neoliberal.
De la interioridad mental a la exterioridad corpórea: una lectura del asco en Beckett
Authors: Jares Luciana Belén
Published: August 2021

A partir de la lectura de “(W)Horoscope”, seis poemas de Echo’s Bones and Other Precipitates y “La mouche” (Beckett, 2007), en este trabajo se buscará plantear cómo el asco articula la relación que establece Samuel Beckett entre el mundo exterior: lo corpóreo, degradado, caduco, y la interioridad del pensamiento del sujeto melancólico que medita sobre la muerte. Este contraste se encuentra atravesado por distintas concepciones del asco que afectan tanto a la mente como al cuerpo. Nos detendremos en el asco en relación con los alimentos, con aquello que se ingiere y, por lo tanto, ingresa en el cuerpo y afecta la mente; en el asco como hastío y melancolía, que surge de un estado de inactividad que hace pensar en la caducidad y la decadencia; y desde allí se abordará la relación del asco con las concepciones cuerpo-cadáver, la degradación corpórea y la meditación sobre la muerte. Estos tres ejes permitirán ejemplificar cómo el interior y el exterior se conectan mediante lo repulsivo en los poemas de Beckett.
Case report: MPN-eo with balanced rearrangement of MPRIP-PDGFRB t(5;17)(q32;p11), responding to low dose imatinib
Authors: Beel Karolien , Ameye Geneviève , Kelver Wim De , Michaux Lucienne
Published: August 2021

We present a young patient with a rare eosinophilic myeloproliferative neoplasm MPN-eo with a balanced rearrangement of MPRIP-PDGFRB t(5;17)(q32;p11). This fusion gene was reported in only one other case in 2015. A personalized molecular test was developed with the diagnostic material of the patient. Our patient is in complete cytogenetic and molecular remission under low dose imatinib, two years after treatment initiation.
Using a research coach to enhance evidence-based practice integration in undergraduate nursing
Authors: D'Souza Melba Sheila
Published: August 2021

Background and objective: Coaching contributes to the understanding and application of knowledge in nursing practice. This study aims to examine the implementation of a research coach to enhance evidence-based practice integration in undergraduate nursing.Methods: Design: This study used a quasi-experimental non-equivalent post-test-only design. Settings and participants: Forty second-year undergraduate nursing students were invited to participate in the study at a public university in 2019. Methods: The evidence-based practice (EBP) questionnaire was used, and the primary outcomes were attitudes, skills, and capabilities of EBP. The undergraduate students worked with a third-year level research coach to engage in evidence-based nursing using clinical case studies. Results: The findings expressed the students’ readiness to capture, select, and organize their critical thinking skills through case studies and online discussion. Students perceived that they needed versatile skills in the interpretation and application of evidence-based nursing.Conclusions: A research coach played an essential role for novice student nurses in improving decision-making skills and transition to practice in this setting. The research coach model enables critical thinking and problem-solving skills through interaction and case studies.
Prevalence and Determinants of Unintended Pregnancy among Women Receiving Antenatal Care Services: A Facility-Based Cross-Sectional Study in Ghana
Authors: Adu-Bonsaffoh Kwame , Tamma Evelyn , Seffah Joseph D
Published: August 2021

Globally, unintended pregnancy represents an important public health challenge with significant social, economic and clinical repercussions which are worse in low-income and middle-income countries. Appropriate use of modern contraceptives averts significant proportions of unintended pregnancies and pregnancy complications. The objective of this study was to determine the prevalence and determinants of unintended pregnancy and explore modern contraceptive use among pregnant women

A cross-sectional study was conducted among pregnant women receiving antenatal care at Korle-Bu Teaching hospital in Ghana using a face-to-face structured interview. Descriptive analysis was performed and multivariable logistic regression was used to assess the determinants of unintended pregnancy.

Among the included 450 pregnant women receiving antenatal care, 155 (34.4%) had unintended pregnancy out of which 33 (21.3%) were using contraceptives prior to conception. In all, 14.2% (64/450) were using modern contraceptives. There was a significant difference between women and their partners regarding the perception of their index pregnancy as unintended (34.4% versus 31.6%, p-value <0.001). Significant determinants of unintended pregnancy include younger maternal age [aOR:5.706, 95%CI (1.860, 19.732)], unmarried status [aOR:5.238, 95%CI (2.882, 9.735)], previous childbirth [(aOR:2.376, 95%CI (1.460, 4.758], number of pregnancies ≥6 [aOR:2.640, 95%CI (1.210, 5.854)], number pregnancies ≤2 [aOR:0.417, 95%CI (0.252, 0.682)], previous caesarean birth [aOR:2.034, 95%CI (1.154, 3.306)] and contraceptive use prior to index pregnancy [aOR:2.305 95%CI (1.283-4.162)].

The prevalence of unintended pregnancy remains markedly high while prior contraceptive use was relatively low among women receiving antenatal care. Evidence-based interventions including specialized client education are vital in improving optimal use of contraceptive services. We recommend further research including community-based qualitative studies to better understand the factors associated with contraceptive uptake and outcomes of unintended pregnancy.
The Blended Instruction on Cloud via an Interactive Augmented Reality Technology Model to Enhance Digital Literacy
Authors: Soutthaboualy Thongkhane , Chatwattana Pinanta , Piriyasurawong Pallop
Published: August 2021

The objectives of the study were 1) Synthesize the conceptual framework of blended instruction on the cloud via an interactive augmented reality technology model to enhance digital literacy, 2) Design the blended instruction on the cloud via an interactive augmented reality technology model, 3) Develop the blended instruction on the cloud via an interactive augmented reality technology model, and 4) Study the suitability assessment of the blended instruction on the cloud via an interactive augmented reality technology model. The proposed model develops digital literacy skills, one of the most important skills for learners in the 21st century that contributes to the learning society in the digital world. The samples group used in the study were nine experts in higher education. Then analyzing the data obtained from the assessment, using mathematic mean and standard deviation. Results of the assessment found the following. 1) The developed teaching and learning model consisted of four components: inputs, blended instruction on cloud processes, outcomes, and feedback. 2) The blended instruction on the cloud processes consists of 3 steps: the preparation, teaching and learning, presentation and summary of the learning results. 3) The assessment of the suitability of the developed teaching and learning model was at the highest appropriate. 4) The suitability assessment in the developed teaching and learning model was at the highest appropriate.
Comparative study between synthetic and dairy wastewaters in single chamber microbial fuel cell for power generation
Authors: Choudhury Payel , Majumdar Ria , Bandyopadhyaya Tarun Kanti
Published: August 2021

To investigate the performance of microbial fuel cell (MFC) with a single-chamber membrane, Pseudomonas aeruginosa is used as a bio catalyst for various synthetic wastewaters rich in carbohydrate and is compared with real dairy wastewater in this experiment. Therefore, the choice of appropriate carbon, nitrogen, NaCl, inoculum content, temperature, and pH process parameters are used for preparing synthetic wastewater was agreed upon by one-variable-at-a time approach. Maximum levels of voltage generation attained from the synthetic wastewater was 485 mV when supple­mented with 1.5 % of lactose as a source of carbon, 0.3 % of ammonium chloride as a decent nitrogen source, 0.03 % of NaCl, inoculum concentration of 3 %, the temperature at 37 oC and pH 7. On the other hand, the maximum voltage attained with real dairy wastewater was 561 mV with high chemical oxygen demand (COD) value of 801 mg l-1. The maximum power density obtained from dairy wastewater was 73.54 mW m-2. Thus, High voltage achieved for MFC operating with real dairy wastewater suggests that it can be used not only for the industrial application to generate more renewable power, but also for the wastewater treatment carried out at the same time.
The role of local anaesthesia in intra-operative pain management in dental practice
Authors: Pasternak Marcin , Woroń Jarosław
Published: August 2021

Intra-operative pain management with the means of local anaesthesia is an important of dental practice. Local anaesthetics are drugs the most commonly used drugs in dentistry, being, at the same time, the safest and most effective pain preventing and pain relieving agents known to medicine.The mechanism of action of local anaesthetics involves interruption of the conduction of nerve impulses. These agents show high affinity for the voltage-dependent sodium channels (Nav), they block them, thus preventing the influx of sodium cations through the membranes of the neuron. The potential threshold is not reached and the potential itself is not present. The potency of local anaesthetic drugs depends primarily on the concentration of the solutions used, while possible side effects depend on the dose. In this paper the characteristics of local anaesthetics used in dental practice were presented as well as characteristics of vasoconstrictors added to anaesthetic solutions. The historical outline, the mechanism of action of local anaesthetics and the currently used both basic and additional methods of anaesthesia are discussed. Possible strategies for improving the effectiveness of anaesthesia by the means of physical and chemical methods were explained. General and local adverse reactions of dental anaesthetics were also discussed, along with ways to prevent and treat them.
The impact of the treatment of chronic pain treatment with
transdermal buprenorphine on functional performance and
risk of falls in elderly people diagnosed with osteoarthritis
Authors: Widenka Marek , Leppert Wojciech
Published: August 2021

The aim of the study was to evaluate the impact of transdermal buprenorphine on overall functional fitness and the risk for falls in the treatment of chronic pain in elderly patients diagnosed with osteoarthritis. Transdermal buprenorphine was used for 10 days in 60 patients over 64 years old in the treatment of severe chronic pain caused by osteoarthritis. Patients were randomly assigned to 3 groups with a starting dose of 8.75 µg/h, 17.5 µg/h, and 35 µg/h, respectively. On day 1 of the study, the Barthel Index, Instrumental Activities of Daily Living (IADL), Mini–Mental State Examination (MMSE), and the Tinetti balance and gait test were used. On the final day of the study, the Tinetti balance and gait test and the Barthel Index were used again. Pain intensity was evaluated every day with the Brief Pain Inventory – Short Form. No differences in IADL scores between patient groups in baseline assessment were found. An improvement in the Barthel Index overall scores was obtained in all patients with no differences between patient groups. An improvement for both balance and gait in all patient groups of the Tinetti test was found. Regarding balance and overall results, a more significant improvement in group 3 compared to groups 1 and 2 was observed. Transdermal buprenorphine provided satisfactory analgesia regardless of the starting dose of the drug with better toleration of lower initial doses: 8.75 µg/h and 17.5 µg/h compared to a starting dose of 35 µg/h. The treatment of elderly patients with severe chronic pain induced by osteoarthritis with different initial doses of transdermal buprenorphine improved overall physical fitness and reduced the risk for falls. The treatment resulted in satisfactory analgesia with less adverse effects in patients who started with lower initial lower doses of transdermal buprenorphine.
30 lat podatku dochodowego od osób fizycznych w Polsce a sądownictwo administracyjne: perspektywa ekonomiczna
Authors: Gajewski Dominik , Joński Kamil
Published: August 2021

Celem niniejszego artykułu jest dokonanie syntetycznego, wspartego analizą danych statystycznych, przeglądu kluczowych zagadnień związanych z obciążeniem sądów administracyjnych sprawami dotyczącymi PIT oraz ich rozpoznawaniem. Zgromadzone dane sugerują, że zgodnie ze znaczeniem fiskalnym PIT – oraz sięgającą dwudziestu milionów liczbą osób składających co roku zeznania podatkowe – skargi dotyczące podatku dochodowego od osób fizycznych pozostają relatywnie liczną grupą spraw podatkowych rozpoznawanych przez sądy administracyjne. Kwestie wydaje się potęgować częstotliwość zmian legislacyjnych, efektywnie wykluczająca bieżące zapoznawanie się podatników z tekstem normatywnym. Trzydziesta rocznica wprowadzenia PIT stanowi okazję do pogłębionego przeglądu adekwatności obecnych rozwiązań do realiów ekonomicznych i struktury rynku pracy.
Czy podatki dochodowe mogą skutecznie wypełniać funkcję redystrybucyjną?
Authors: Kuzińska Hanna
Published: August 2021

Redystrybucja dochodu narodowego polega między innymi na zmniejszaniu różnic dochodowych przy pomocy podatków. Realizacji tego celu służą głównie podatki dochodowe i majątkowe a w małym stopniu podatki pośrednie, które nie odwołują się do majętności podatnika, czyli do tzw. zdolności płatniczej. Redystrybucja służy zmniejszeniu koncentracji dochodów, która mierzona jest współczynnikiem Giniego. Współczynnik ten w 2018 r. był w Polsce wyższy niż w Słowenii, Słowacji, Norwegii, Szwecji czy Danii, ale niższy niż w Hiszpanii, Portugalii, Bułgarii czy Rumunii. Jeśli celem polityki fiskalnej jest zmniejszanie koncentracji dochodu, należałoby zwiększyć opodatkowanie dochodów osobistych, zwłaszcza tych wyższych oraz opodatkowanie zysków firm. Rodzi to pytanie o warunki brzegowe, które powinna spełniać na nowo zbudowana skala podatkowa, która mogłaby łagodzić regresywność opodatkowania podatkami pośrednimi.
Opodatkowanie duchownych – czy konstrukcja ryczałtu wymaga zmian?
Authors: Klimiuk Wiktor
Published: August 2021

Artykuł ma na celu przedstawienie zasad opodatkowania osób duchownych w Polsce oraz problemów pojawiających się w związku ze strukturą tego opodatkowania. Samo opodatkowanie, mimo że obowiązuje od 1998 r., jest stosunkowo mało znane a jego konstrukcja, pomimo zdiagnozowanych problemów nie ulega zmianom. Okres pandemii po raz kolejny pokazuje na nieprzystosowanie obowiązującego systemu do obecnych realiów. Artykuł ma być asumptem do dyskusji na temat roli i konstrukcji opodatkowania osób duchownych w obecnym otoczeniu prawnym i społecznym.
Interlinkages between Urbanization and Climate Change: Identifying and Understanding the Challenges and the Prospects
Authors: Alakshendra Abhinav , Kumar Arjun , Mehta Simi
Published: August 2021

India is urbanizing at an alarming rate and the impact of climate change is becoming more visible each passing day. The rapid urbanization and climate change have severe direct and indirect consequences, such as increasing poverty, inequality, massive displacement, public health concerns, and challenges of urban governance, among others. This paper identifies some of the most pressing issues faced by urban India in the context of climate change. It also details the interventions undertaken at the local, national, and international levels to counter the effect of the climate change. In addition, it critically evaluates the role of government organizations, especially in terms of undertaking regulatory and planning functions. The paper argues that the implementation of institutional reforms would enable the government to reach out to the private sector to improve urban service delivery. It also provides examples of best practices from India and the world in combating climate change through adaptation and mitigation approaches.Abstrak. India mengalami urbanisasi pada tingkat yang mengkhawatirkan dan dampak perubahan iklim menjadi terlihat setiap hari. Urbanisasi yang cepat dan perubahan iklim memiliki konsekuensi langsung dan tidak langsung yang parah, seperti antara lain meningkatnya kemiskinan, ketimpangan, pengungsian besar-besaran, masalah kesehatan masyarakat, dan tantangan tata kelola kota. Makalah ini mengidentifikasi beberapa masalah paling mendesak yang dihadapi oleh perkotaan India dalam konteks perubahan iklim. Makalah ini juga merinci intervensi yang dilakukan di tingkat lokal, nasional, dan internasional untuk melawan dampak perubahan iklim. Selain itu, secara kritis makalah ini mengevaluasi peran organisasi pemerintah, terutama dalam menjalankan fungsi pengaturan dan perencanaan. Makalah ini berpendapat bahwa pelaksanaan reformasi kelembagaan akan memungkinkan pemerintah menjangkau sektor swasta untuk membantu meningkatkan pelayanan perkotaan. Makalah ini juga memberikan contoh praktik terbaik dari India dan dunia dalam memerangi perubahan iklim melalui pendekatan adaptasi dan mitigasi.Kata kunci. Urbanisasi, perubahan iklim, keterkaitan, tata kelola kota, mitigasi.
Dietary encapsulated Bifidobacterium animalis and Agave fructans improve growth performance, health parameters, and immune response in broiler chickens
Authors: Hernández-Granados María José , Ortiz-Basurto Rosa Isela , Jiménez-Fernández Maribel , García-Munguía Carlos Alberto , Franco-Robles Elena
Published: August 2021

Objective: The present study was conducted to evaluate the effects of dietary supplementation with Bifidobacterium animalis, Agave fructans, and symbiotic of both encapsulated on growth performance, feed efficiency, blood parameters, and immune status in broiler chickens, and to compare these with diets including antibiotic growth promoters and without additives.Methods: A comparative experimental study was carried out with 135 male Ross 308 broiler chickens. Each trial was divided into 5 equal groups. Control group (CON) received a standard diet without growth promoter; GPA, a standard diet with colistin sulfate and zinc bacitracin (0.25 g/kg of feed); PRE, a standard diet with 1% Agave fructans; PRO, a standard diet with Bifidobacterium animalis (11.14±0.70 log CFU/g); SYM, a standard diet with B. animalis and Agave fructans.Results: A significant decrease in food consumption was found for the GPA, PRE, and SYM, compared to the CON group. The results show a better feed conversion index in PRE and GPA with respect to the CON group with the highest conversion index. Interestingly, the weight of the gastrointestinal tract shows a statistically significant difference between GPA and PRE groups. Moreover, the length of the gastrointestinal tract of the GPA group was less than the PRE group. In the total leukocyte count, there was a statistically significant increase in the GPA group compared to the CON, PRE, and PRO groups, and the heterophiles-lymphocytes index was lower in PRO. Regarding the cytokines, interleukin 10 (IL-10) decreased in PRO compared to CON and PRE, while IL-1β increased in the SYM group.Conclusion: Alternative treatments were shown to achieve similar productive results as growth-promoting antibiotics and showed improvement over diet without additives; however, they have immunomodulatory properties and improved the development of the gastrointestinal tract compared to the treatment of growth-promoting antibiotics.
Plasma metabolites associated with physiological and biochemical indexes indicate the effect of caging stress on mallard ducks (Anas platyrhynchos)
Authors: Zheng Chao , Wu Yan , Liang Zhen Hua , Pi Jin Song , Cheng Shi Bin , Wei Wen Zhuo , Liu Jing Bo , Lu Li Zhi , Zhang Hao
Published: August 2021

Objective: Cage rearing has critical implications for the laying duck industry because it is convenient for feeding and management. However, caging stress is a type of chronic stress that induces maladaptation. Environmental stress responses have been extensively studied, but no detailed information is available about the comprehensive changes in plasma metabolites at different stages of caging stress in ducks. We designed this experiment to analyze the effects of caging stress on performance parameters and oxidative stress indexes in ducks.Methods: Liquid chromatography tandem mass spectrometry (LC/MS-MS) was used to determine the changes in metabolites in duck plasma at 5 (CR5), 10 (CR10), and 15 (CR15) days after cage rearing and traditional breeding (TB). The associated pathways of differentially altered metabolites were analyzed using Kyoto encyclopedia of genes and genomes (KEGG) database.Results: The results of this study indicate that caging stress decreased performance parameters, and the plasma total superoxide dismutase levels were increased in the CR10 group compared with the other groups. In addition, 1,431 metabolites were detected. Compared with the TB group, 134, 381, and 190 differentially produced metabolites were identified in the CR5, CR10, and CR15 groups, respectively. The results of principal component analysis (PCA) show that the selected components sufficiently distinguish the TB group and CR10 group. KEGG analysis results revealed that the differentially altered metabolites in duck plasma from the CR5 and TB groups were mainly associated with ovarian steroidogenesis, biosynthesis of unsaturated fatty acids, and phenylalanine metabolism.Conclusion: In this study, the production performance, blood indexes, number of metabolites and PCA were compared to determine effect of the caging stress stage on ducks. We inferred from the experimental results that caging-stressed ducks were in the sensitive phase in the first 5 days after caging, caging for approximately 10 days was an important transition phase, and then the duck continually adapted.
Alterations of mRNA and lncRNA profiles associated with the extracellular matrix and spermatogenesis in goats
Authors: Chen Haolin , Miao Xiaomeng , Xu Jinge , Pu Ling , Li Liang , Han Yong , Mao Fengxian , Ma Youji
Published: August 2021

Objective: Spermatozoa are produced within the seminiferous tubules after sexual maturity. The expression levels of mRNAs and lncRNAs in testicular tissues are different at each stage of testicular development and are closely related to formation of the extracellular matrix (ECM) and spermatogenesis. Therefore, we set out to study the expression of lncRNAs and mRNAs during the different developmental stages of the goat testis.Methods: We constructed 12 RNA libraries using testicular tissues from goats aged 3, 6, and 12 months, and studied the functions of mRNAs and lncRNAs using the gene ontogeny (GO) and Kyoto encyclopedia of genes and genomes (KEGG) databases. Relationships between differentially expressed genes (DEGs) were analyzed by lncRNA-mRNA coexpression network and protein-protein interaction network (PPI). Finally, the protein expression levels of matrix metalloproteinase 2 (MMP2), insulin-like growth factor 2 (IGF2), and insulin-like growth factor-binding protein 6 (IGFBP6) were detected by western blotting.Results: We found 23, 8, and 135 differentially expressed lncRNAs and 161, 12, and 665 differentially expressed mRNAs that were identified between 3 vs 6, 6 vs 12, and 3 vs 12 months, respectively. GO, KEGG, and PPI analyses showed that the differential genes were mainly related to the ECM. Moreover, MMP2 was a hub gene and co-expressed with the lncRNA TCONS-0002139 and TCONS-00093342. The results of quantitative reverse-transcription polymerase chain reaction verification were consistent with those of RNA-seq sequencing. The expression trends of MMP2, IGF2, and IGFBP6 protein were the same as that of mRNA, which all decreased with age. IGF2 and MMP2 were significantly different in the 3 vs 6-month-old group (p<0.05).Conclusion: These results improve our understanding of the molecular mechanisms involved in sexual maturation of the goat testis.
Physicochemical properties of reduced-salt cured pork loin as affected by different freezing temperature and storage periods
Authors: Kim Haeun , Chin Koo Bok
Published: August 2021

Objective: The objective of this study was to evaluate functional properties of reduced-salt pork meat products made of pre-rigor pork loin treated by different freezing temperatures (–30°C and –70°C) during storage.Methods: Pre-rigor cured pork loin with 1.0% added salt was compared to post-rigor muscle added with 1.5% salt for pH, color (L*, a*, b*), cooking loss (CL), expressible moisture, warner-Bratzler shear value, thiobarbituric acid reactive substances (TBARS), and volatile basic nitrogen (VBN).Results: Pre-rigor cured pork loins had higher pH and temperature than post-rigor ones as raw meat (p<0.05). pH values were higher for pre-rigor pork loins than those of post-rigor pork loins (p<0.05). Color values did not different among treatments (p>0.05). No color differences were observed during storage period after cooking (p>0.05). The CL (%) of pre-rigor cured pork loins was the lowest when frozen at –70°C. The TBARS and VBN increased from 8 weeks of storage (p<0.05), but no further changed thereafter (p>0.05). Pre-rigor cured pork loins added with 1.0% salt showed similar characteristics to post-rigor pork loins added with 1.5% salt.Conclusion: Cured pork loins could be produced using pre-rigor muscle added with 1/3 of the original salt level (1.5%) and could be stored for up to 4 wks of frozen storage, regardless of a frozen temperature of –30°C or –70°C without detrimental effects.
AANMF: Attribute-Aware Attentional Neural Matrix Factorization
Authors: Zheng Bo , Hu Jinsong
Published: August 2021

Matrix Factorization (MF) is one of the most intuitive and effective methods in the Recommendation System domain. It projects sparse (user, item) interactions into dense feature products which endues strong generality to the MF model. To leverage this interaction, recent works use auxiliary information of users and items. Despite effectiveness, irrationality still exists among these methods, since almost all of them simply add the feature of auxiliary information in dense latent space to the feature of the user or item. In this work, we propose a novel model named AANMF, short for Attribute-aware Attentional Neural Matrix Factorization. AANMF combines two main parts, namely, neural-network-based factorization architecture for modeling inner product and attention-mechanism-based attribute processing cell for attribute handling. Extensive experiments on two real-world data sets demonstrate the robust and stronger performance of our model. Notably, we show that our model can deal with the attributes of user or item more reasonably. Our implementation of AANMF is publicly available at https://github.com/Holy-Shine/AANMF.
A Novel CCA-Secure Verifiable Authenticated Encryption Scheme Using BSDH and q-SDH Assumptions
Authors: Lin Han-Yu
Published: August 2021

When it comes to secure transactions online, the requirements of confidentiality and authenticity are usually concerned the most. The former prevents unauthorized reading, while the latter ensures authorized access. Hybrid cryptographic mechanisms such as authenticated encryption (AE) schemes, simultaneously combine the functions of public key encryption and digital signature. Some AE schemes also provide a cost-free arbitration mechanism to deal with the signer’s later repudiation. Such schemes have been found to have numerous practical applications like on-line credit card transactions, confidential contract signing and the protection of digital evidence, etc. However, a designated verifier should also have the ability to convince any third party that he/she is indeed the intended recipient. In this paper, the author presents a novel verifiable authenticated encryption (VAE) scheme with the functionality of recipient proof. Furthermore, the paper shows that the proposed VAE scheme is non-delegatable and provably secure under the random oracle proof models. A non-delegatable hybrid cryptographic scheme provides a higher security level even if the shared common key is compromised. Specifically, the author of the paper will demonstrate that the designed construction is proved secure against adaptive chosen-ciphertext attacks (CCA2) assuming the hardness of Bilinear Square Diffie-Hellman Problem (BSDHP) and secure against adaptive chosen-message attacks (CMA) assuming the hardness of q-Strong Diffie-Hellman Problems (q-SDHP).
Parallel Implementation of Improved K-Means Based on a Cloud Platform
Authors: Zhang Shufen , Liu Zhiyu , Chen Xuebin , Luo Changyin
Published: August 2021

In order to solve the problem of traditional K-Means clustering algorithm in dealing with large-scale data set, a Hadoop K-Means (referred to HKM) clustering algorithm is proposed. Firstly, according to the sample density, the algorithm eliminates the effects of noise points in the data set. Secondly, it optimizes the selection of the initial center point using the thought of the max-min distance. Finally, it uses a MapReduce programming model to realize the parallelization. Experimental results show that the proposed algorithm not only has high accuracy and stability in clustering results, but can also solve the problems of scalability encountered by traditional clustering algorithms in dealing with large scale data.
Tracking Video Target via Particle Filtering on Manifold
Authors: Ge Huilin , Zhu Zhiyu , Lou Kang
Published: August 2021

Most of existing particle filtering-based video target tracking algorithms are in Euclidean space, when object posture and scale size changes, and to track high dimensional system, it is difficult to guarantee the tracking effect. This paper describes the covariance descriptor to represent the object image region, the geometric deformation of the object image region can be realized by an affine transformation, and the affine transformation matrix is one element of the Lie group. Then particle filter algorithm based on lie group of manifold is proposed , the video tracking system state lies directly on a low dimensional manifold, state samples are drawn moving on the manifold geodesics, thus state space of intrinsic geometrical characteristic can be in full use, which provides a new idea for improving the tracking efficiency and robustness. Simulation results show that object in the case of geometric deformation including scale size changes, rotating, etc. The proposed manifold particle filtering algorithm can still realize target tracking well and improve the real-time performance.
Die Klimaschutzgesetze der Bundesländer
Authors: Beye Constantin
Published: August 2021

This work offers a comprehensive analysis of the climate protection laws of the German federal states with regard to their systematics and places them in the relevant context of international, European and federal law. The focus of the analysis is on the legal effects and the scope of competence of the German federal states. In particular, the regulatory content of the laws is explored. A central aspect is the effectiveness of these climate protection laws.

In this way, the work contributes to the scientific development of climate protection law, but also of sub-areas of energy law. At the same time, it serves as an orientation for legislators an administration.
Die Freiwilligkeit der datenschutzrechtlichen Einwilligung bei unentgeltlichen Dienstleistungen im Internet
Authors: Bender Anouk Marie
Published: August 2021

Providers of free internet services regularly link the provision of their services to consent to the commercial processing of user data. Users often respond to such consent requests by quickly declaring their consent. In doing so, many users spend little time considering the modalities of data processing and the potential consequences of data use.

By law, consent only legitimizes processing if it is given voluntarily. This dissertation therefore aims to analyze the challenges for voluntary consent in the context of Internet services and develops a proposal for solving the challenges presented.
Audiovisual independente: política de fomento e organização das produtoras no Brasil
Authors: Morais Kátia
Published: August 2021

A obra vem preencher uma carência de reflexões e publicações no país sobre o tema com uma metodologia rigorosa que dá conta da complexidade desta arte como fenômeno social, de suas especificidades e de sua dinâmica, não apenas na produção, mas também na circulação e fruição. A política audiovisual e a produção independente no Brasil estão aqui atualizadas, incluindo a participação da televisão como janela de exibição estratégica para o conteúdo nacional e como parte da política audiovisual.
Distributed functions of prefrontal and parietal cortices during sequential categorical decisions
Authors: Zhou Yang , Rosen Matthew C , Swaminathan Sruthi K , Masse Nicolas Y , Zhu Ou , Freedman David J
Published: August 2021

Comparing sequential stimuli is crucial for guiding complex behaviors. To understand mechanisms underlying sequential decisions, we compared neuronal responses in the prefrontal cortex (PFC), the lateral intraparietal (LIP), and medial intraparietal (MIP) areas in monkeys trained to decide whether sequentially presented stimuli were from matching (M) or nonmatching (NM) categories. We found that PFC leads M/NM decisions, whereas LIP and MIP appear more involved in stimulus evaluation and motor planning, respectively. Compared to LIP, PFC showed greater nonlinear integration of currently visible and remembered stimuli, which correlated with the monkeys’ M/NM decisions. Furthermore, multi-module recurrent networks trained on the same task exhibited key features of PFC and LIP encoding, including nonlinear integration in the PFC-like module, which was causally involved in the networks’ decisions. Network analysis found that nonlinear units have stronger and more widespread connections with input, output, and within-area units, indicating putative circuit-level mechanisms for sequential decisions.
Augmin deficiency in neural stem cells causes p53-dependent apoptosis and aborts brain development
Authors: Viais Ricardo , Fariña-Mosquera Marcos , Villamor-Payà Marina , Watanabe Sadanori , Palenzuela Lluís , Lacasa Cristina , Lüders Jens
Published: August 2021

Microtubules that assemble the mitotic spindle are generated by centrosomal nucleation, chromatin-mediated nucleation, and nucleation from the surface of other microtubules mediated by the augmin complex. Impairment of centrosomal nucleation in apical progenitors of the developing mouse brain induces p53-dependent apoptosis and causes non-lethal microcephaly. Whether disruption of non-centrosomal nucleation has similar effects is unclear. Here, we show, using mouse embryos, that conditional knockout of the augmin subunit Haus6 in apical progenitors led to spindle defects and mitotic delay. This triggered massive apoptosis and abortion of brain development. Co-deletion of Trp53 rescued cell death, but surviving progenitors failed to organize a pseudostratified epithelium, and brain development still failed. This could be explained by exacerbated mitotic errors and resulting chromosomal defects including increased DNA damage. Thus, in contrast to centrosomes, augmin is crucial for apical progenitor mitosis, and, even in the absence of p53, for progression of brain development.
Assessing low-level cognitive processes of word recognition
Authors: Holsworth Michael
Published: August 2021

A fundamental skill required for vocabulary development is word recognition ability. According to Perfetti (1985), word recognition ability relies on low-level cognitive processing skill to be automatic and efficient in order for cognitive resources to be allocated to high-level processes such as inferencing and schemata activation needed for reading comprehension. The low-level processes include orthographic knowledge, semantic knowledge, and phonological awareness. These low-level processes must be efficient, fluent, and automatic in second language readers in order for them to achieve the ultimate goal of reading comprehension. This article briefly describes the concept of word recognition, its relation to vocabulary, and three tests that were designed to measure the three components of word recognition (orthographic, semantic, and phonological knowledge) in a longitudinal study that investigated the effects of word recognition training on reading comprehension.
Architecture of the Musculus Uvulae- A Review
Authors: Daisy L , Surraj S , Mrudula C , Sushma P Rao
Published: August 2021

The architecture of the musculus uvulae is subject to controversy, especially with regard to its crucial role in maintaining the morphology of the cleft palate, and its involvement in surgical procedures of palate repair. Its functional role in the closure of the velum and elevation of the same leading to voice changes are also an element of debate. The fate and orientation of its muscle fibres and its reinforcement with other related muscles of the palate raise concerns with regard to its functional role. Its positioning in the soft palate would give us an insight on the exact role played by this muscle in velopharyngeal closure. Its nerve supply also remains shrouded by various theories without conclusive evidence. Hence, this review aims to highlight its morphological role for the same.
AYURVEDIC MANAGEMENT OF PAKSHAGHATA (ISCHAEMIC STROKE): CASE REPORT
Authors: Sasikumar Shilpa , S G Vipin
Published: August 2021

Stroke occurs when there is interrupted blood supply to a part of brain or when the blood supply is reduced, leads to brain cell damage. Stroke is mainly of two types: ischemic and haemorrhagic stroke. Ischemic type of stroke is the most common type. The prevalence of stroke is approximately 250 per 1 lakh person and 9.95 percent of total death. The present case reported to the Sri Jayendra Saraswathi Ayurveda college and hospital, Nazarathpettai, Chennai, Tamilnadu with the complaints of inability to move left hand and left leg with the history of stroke 6 months back, also had slurred speech. This patient’s condition improved very well by internal medicines and panchakarma procedures. At the end of the treatment the patient’s upper and lower limbs range of movements and functions improved. There was also considerable recovery in the mobility, mode, energy and language ability. Recovery was promising and worth documenting.
Performance of Mung Bean (Vigna radiata L. Wilczek) Influenced by Plant Population and NPS Fertilizer Rates in Bako
Authors: Sefera Gezahegn Biru , Ashagre Habtamu , Abraham Thomas
Published: August 2021

Mung bean (Vigna radiata L.) is a leguminous crop with a tremendous potential in achieving food and nutritional security in Ethiopia in future. In addition, mung bean plays a major role in improving soil nitrogen content through atmospheric nitrogen fixation, thus reducing the dependance on synthetic nitrogenous fertilizers. However, its productivity is limited by inadequate plant population and NPS fertilizer rate in the study area. Hence, this study was carried out to determine the optimum plant population and NPS fertilizer rates for mung bean borda variety in Bako. The experiment comprised of factorial combinations of four different plant populations (500000, 571429, 666667, and 800000 plants ha-1) and five NPS fertilizer rates (0, 50, 100, 150 and 200 kg ha-1) and it was laid out using Randomised Complete Block Design with three replications. Results indicated that main effect of plant population and NPS fertilizer rates had significant effect on phenology, growth, yield, and yield components of mung bean, except stand count, above-ground biomass, straw and seed yield, which were affected by the main factors and their interactions. Highest nodule dry weight per plant (0.14g), number of pods per plant (4.74 g), weight of seeds per pod (10.26 g), 100-seed weight (3.61g), and harvest index (31.16%) were observed under minimum plant population (500,000 plants ha-1). Moreover, effective nodules per plant (2.28), nodule fresh weight (0.33 gm), nodule dry weight (0.141g plant-1), number of pods per plant (4.79), seeds per pod (10.78 g), 100-seed weight (3.73 g) and harvest index (32.98%) were observed under 200 kg ha-1 NPS fertilizer rate. Highest stand count per hectare (780,667 plants ha−1), above-ground biomass (4,947kg ha-1), seed yield ha-1 (1,371kg ha-1) and straw yield (3,575 kg ha-1) were recorded at higher plant population (800,000 plants ha-1) with 200kg NPS ha-1 fertilizer rate. However, higher plant population (800,000 plants ha-1) at the rate of 100 kg NPS ha-1 fertilizer produced1, 325 kg ha-1seed yield which was the highest net benefit (50,080 TB) and marginal rate of returns (5,610.8%). Therefore, application of 100 kg NPS ha-1 fertilizer rate with plant population of 800,000 plants ha-1 can be recommended for mung bean production in the study area and similar agro-ecologies. However, the current study was carried out only in one location for one cropping season, hence further studies over many seasons and across several locations are needed to have a conclusive recommendation for wide range of agro-ecologies for mung bean production.
Binary Logistic Regression Analysis on Predicting Academics Performance
Authors: Akinyem E. K. , Ogunleye O. A. , Olaoye H.O , Brakoru J.
Published: August 2021

This paper considers the application of logistic regression model to predict academics performance of students. The choice of this model becomes imperative as a result of dichotomous relationship existing in the model (either pass or fail). 100 students from the four department where engaged in the study. Statistical package for social scientist (SPSS) was used for the analysis. The results show that monthly allowance of students, and study time of the students were significant predictors. While gender and educational level of parent were insignificant predictors. The fitness of the model was assessed using Hosmer and Lemeshow test, split-sample approach and other supplementary indices to validate the model. The fitted model indicated that fitted binary logistic regression model could be used to predict the future performance of students.
Study of Plasminogen Activator Inhibitor-1 (PAI-1) as Prognostic Marker in Sepsis
Authors: Elnomany Amal Abdelaziz Abdellatif , Hodeib Hossam Abd El Mohsein , Elbaradey Ghada Fouad , Sweilam Mohammad Abdelrahman
Published: August 2021

Background: Sepsis is an unorganized host response to infection that is manifested by the failure of organs and DIC and systemic coagulation due to failure of Plasmin as an important fibrin lytic protein that is regulated by plasminogen activators and inhibitors. Our theory is that elevated PAI-1 may have a role in multi-system organ failure in patients with septicemia and systemic coagulopathy.

Aim: to evaluate plasminogen activator inhibitor-1 as a prognostic factor in patients with septicemia and DIC.

Patients and Methods: 60 cases with septicemia and in shock, in addition to 20 healthy individuals. Cases were selected from surgical ICU, Tanta University hospitals. Normal healthy subjects were matched by age and gender with the patients' group.

Results: Respiratory system and urinary tract infections, were the most common infections and high SOFA and APACHE scores in the selected cases.  The hematological findings in septic patients are anemia, thrombocytopenia, and leukocytosis. There was a significant increase in urea, creatinine, SGOT, SGPT levels, and CRP in patient groups. Higher levels of PAI-1 in cases suffering sepsis. An increased mortality rate after 28 days of follow-up was noticeable in cases with established septic shock compared to other patient groups in Tanta university surgical intensive care. We found a direct correlation between PAI-1and SOFA, APACHE, bilirubin, creatinine, PT, APTT, and Procalcitonin.

Conclusions: PAI-1 level has a prognostic value in cases with infections or septicemia presented to our emergency center.