Device-assessed sleep and physical activity in individuals recovering from a hospital admission for COVID-19: a multicentre study
Authors: Plekhanova Tatiana , Rowlands Alex V. , Evans Rachael A. , Edwardson Charlotte L. , Bishop Nicolette C. , Bolton Charlotte E. , Chalmers James D. , Davies Melanie J. , Daynes Enya , Dempsey Paddy C. , Docherty Annemarie B. , Elneima Omer , Greening Neil J. , Greenwood Sharlene A. , Hall Andrew P. , Harris Victoria C. , Harrison Ewen M. , Henson Joseph , Ho Ling-Pei , Horsley Alex , Houchen-Wolloff Linzy , Khunti Kamlesh , Leavy Olivia C. , Lone Nazir I. , Marks Michael , Maylor Ben , McAuley Hamish J. C. , Nolan Claire M. , Poinasamy Krisnah , Quint Jennifer K. , Raman Betty , Richardson Matthew , Sargeant Jack A. , Saunders Ruth M. , Sereno Marco , Shikotra Aarti , Singapuri Amisha , Steiner Michael , Stensel David J. , Wain Louise V. , Whitney Julie , Wootton Dan G. , Brightling Christopher E. , Man William D-C. , Singh Sally J. , Yates Tom ,   Writing group (on behalf of the PHOSP-COVID Collaborative Group)
Published: July 2022

Background

The number of individuals recovering from severe COVID-19 is increasing rapidly. However, little is known about physical behaviours that make up the 24-h cycle within these individuals. This study aimed to describe physical behaviours following hospital admission for COVID-19 at eight months post-discharge including associations with acute illness severity and ongoing symptoms.

Methods

One thousand seventy-seven patients with COVID-19 discharged from hospital between March and November 2020 were recruited. Using a 14-day wear protocol, wrist-worn accelerometers were sent to participants after a five-month follow-up assessment. Acute illness severity was assessed by the WHO clinical progression scale, and the severity of ongoing symptoms was assessed using four previously reported data-driven clinical recovery clusters. Two existing control populations of office workers and individuals with type 2 diabetes were comparators.

Results

Valid accelerometer data from 253 women and 462 men were included. Women engaged in a mean ± SD of 14.9 ± 14.7 min/day of moderate-to-vigorous physical activity (MVPA), with 12.1 ± 1.7 h/day spent inactive and 7.2 ± 1.1 h/day asleep. The values for men were 21.0 ± 22.3 and 12.6 ± 1.7 h /day and 6.9 ± 1.1 h/day, respectively. Over 60% of women and men did not have any days containing a 30-min bout of MVPA. Variability in sleep timing was approximately 2 h in men and women. More severe acute illness was associated with lower total activity and MVPA in recovery. The very severe recovery cluster was associated with fewer days/week containing continuous bouts of MVPA, longer total sleep time, and higher variability in sleep timing. Patients post-hospitalisation with COVID-19 had lower levels of physical activity, greater sleep variability, and lower sleep efficiency than a similarly aged cohort of office workers or those with type 2 diabetes.

Conclusions

Those recovering from a hospital admission for COVID-19 have low levels of physical activity and disrupted patterns of sleep several months after discharge. Our comparative cohorts indicate that the long-term impact of COVID-19 on physical behaviours is significant.