bluuebunny/crossref_metadata_2025 huggingface dataset:
NO Synthase but not NO, HNO or H2O2 Mediates Endothelium-Dependent Relaxation of Resistance Arteries from Patients with Resistant Cardiovascular Disease
Authors: Matthies Maximilian , Rosenstand Kristoffer , Nissen Inger , Muitjens Stan , Riber Lars , Mey Jo De , Bloksgaard Maria
Published: February 2021

Background and Purpose: Superoxide anions can reduce the bioavailability
and actions of endothelium-derived NO. In human resistance-sized
arteries, endothelium-dependent vasodilatation can be mediated by H2O2
instead of NO. We tested the hypotheses that in resistance arteries from
patients with resistant cardiovascular disease (CVD),
endothelium-dependent vasodilatation uses mechanisms that are either
insensitive to oxidative stress or involve a reactive oxygen species.
Experimental Approach: Small arteries were isolated from biopsies of the
parietal pericardium of patients undergoing elective cardiothoracic
surgery and were studied by immunohistochemical and organ chamber
techniques. Key Results: NO-synthases 1, 2 and 3, superoxide dismutase 1
and catalase proteins were observed in the microvascular wall. Relaxing
responses to bradykinin were endothelium dependent. During submaximal
depolarization-induced contraction, these relaxations were inhibited by
inhibitors of NO-synthases (NOS) and soluble guanylyl cyclase (sGC) but
not by scavengers of NO or HNO, inhibitors of cyclooxygenases, neuronal
NO-synthase, superoxide dismutase or catalase, or by exogenous catalase.
During contraction stimulated by endothelin-1, these relaxations were
not reduced by any of these interventions except DETCA which caused a
small reduction. Conclusion and Implications: In resistance arteries
from patients with resistant CVD, endothelium-dependent relaxations seem
not to be mediated by NO, HNO or H2O2 although NOS and sGC can be
involved. These vasodilator responses proceed during excessive oxidative
stress.
Coexisting with cheaters: Microbial exoenzyme production as a snowdrift game model
Authors: Xenophontos Constantinos , Harpole Stanley , Kuesel Kirsten , Clark Adam
Published: February 2021

Cheating in microbial communities is often regarded as a precursor to a
“tragedy of the commons”, ultimately leading to over-exploitation by a
few species, and destabilisation of the community. However, this view
does not explain the ubiquity of cheaters in nature. Indeed, existing
evidence suggests that cheaters are not only evolutionarily and
ecologically inevitable, but also play important roles in communities,
like promoting cooperative behaviour. We developed a chemostat model
with two microbial species and a single, complex nutrient substrate. One
of the organisms, an enzyme producer, degrades the substrate, releasing
an essential and limiting resource that it can use both to grow and
produce more enzymes, but at a cost. The second organism, a cheater,
does not produce the enzyme but benefits from the diffused resource
produced by the other species, allowing it to benefit from the public
good, without contributing to it. We investigated evolutionarily stable
states of coexistence between the two organisms and described how enzyme
production rates and resource diffusion influence organism abundances.
We found that, in the long-term evolutionary scale, monocultures of the
producer drive themselves extinct because selection always favours
mutant invaders that invest less in enzyme production. However, the
presence of a cheater buffers this runaway selection process, preventing
extinction of the producer and allowing coexistence. Resource diffusion
rate controls cheater growth, preventing it from outcompeting the
producer. These results show that competition from cheaters can force
producers to maintain adequate enzyme production to sustain both itself
and the cheater. This is known in evolutionary game theory as a
“snowdrift game” – a metaphor describing a snow shoveler and a
cheater following in their clean tracks. We move further to show that
cheating can stabilise communities and possibly be a precursor to
cooperation, rather than extinction.
Adenocarcinoma of ectopic pancreas
Authors: Kalaji Manhal
Published: February 2021

Ectopic pancreas adenocarcinoma is a very rare form of aberrant
pancreas. It is part of differential diagnosis of submucosal tumors. The
final diagnosis is based on the histological analysis. Surgery is the
standard treatment for those tumours. This case illustrates this
pathology.
Vertical transmission of methicillin-resistant Staphylococcus aureus at delivery and its clinical impact: an observational, prospective cohort study
Authors: Ogura Jumpei , Inayama Yoshihide , Sasamoto Naoko , Hirayama Takahiro , Ohara Tsutomu , Sakai Mie , Suzuki Haruka , Yasumoto Koji , Suginami Koh , Yamanoi Koji
Published: February 2021

Objectives: To accurately assess the vertical transmission rate of
Methicillin-resistant Staphylococcus aureus (MRSA) and its clinical
impacts on pregnant mothers and neonates. Design: A prospective
observational cohort study. Setting: Japan. Population: 898 pregnant
women and their 905 neonates delivered in gestation week >
32+0 at Toyooka Hospital from August 2016 to December 2017. Methods:
MRSA was cultured from the nasal and vaginal samples taken from mothers
at enrollment and the nasal and umbilical samples taken from neonates
immediately after their birth. We examined the vertical transmission
rate of MRSA in mother-neonate pairs. We used multivariable logistic
regression to identify maternal/neonatal adverse outcomes associated
with maternal MRSA colonization. Main outcome measures: The frequency of
maternal/neonatal MRSA colonization and adverse outcomes. Results: The
prevalence of maternal MRSA colonization was 6.1% (55/898), and that of
neonates was 0.8% (8/905). The prevalence of neonatal MRSA was 12.7%
(7/55 mother-neonate pairs) in the MRSA-positive mothers, whereas it was
only 0.12% (1/843 pairs) in the MRSA-negative mothers (OR: 121, 95%
CI: 14.6-1000). When the maternal vaginal-MRSA was positive, the
vertical transmission rate was 44.4% (4/9). Skin and soft tissue
infections (SSTIs) developed significantly more frequently in neonates
born to the MRSA-positive mothers (OR: 7.47, 95% CI: 2.50-22.3).
Conclusions: The prevalence of MRSA in pregnant women was approximately
6%. The vertical transmission rate of vaginal MRSA was as high as
44.4%. Maternal MRSA colonization is associated with increased
development of neonatal SSTIs via vertical transmission.
CAN FERRITIN / LYMPHOCYTE PERCENTAGE RATIO, A NEW INDICATOR, PREDICT THE CLINICAL COURSE OF COVID-19 CASES?
Authors: AYGUN Huseyin , ERAYBAR Suna
Published: February 2021

Aim: Covid-19 maintains its seriousness as a global emergency with its
rapid distribution worldwide. Ferritin / lymphocyte percentage ratio
(FLPR) may appear as a prognostic value at the initial evaluation stage
and thus can be used as a simple, effective and reliable parameter in
critical patient identification with Covid-19. Materials and Methods: In
this retrospective cohort study we evaluated patients over 18 years old,
who were hospitalized after being evaluated as COVID-19 and whose PCR
results were positive. We calculated FLPRs from complete blood counts
taken during emergency department admissions and classified disease
severity due to emergency initial evaluation. The relationship between
the severity of the thoracic tomography findings, hospitalization and
intensive care needs, and 28-day mortality with the FLPR were evaluated.
Results: The difference between the groups classified according to
COVID-19 severity and the FLPR means was statistically significant (x2 =
148,284; SD = 3; p = 0,000). FLPR levels were found to be high in
critical and serious groups. In the ROC analysis for the FLPR level, the
area under the curve (AUC) value was found to be 0.909 (95% CI
0.857-0.961). When the cut off value of FLPR was 9.80, the sensitivity
was found to be 97.6%, and the specificity was 65.2%, whereas, when
the cut off value for FLPR was found to be 21.11, the sensitivity was
82.9% and the specificity was 82.8%. Conclusion: The FLPR, a new
parameter, can be used as a significant marker to predict the 28-day
mortality patients.
Risk factors for acute kidney injury in elderly patients after coronary artery bypass grafting: A Chinese population
Authors: Hou Xuejian , Liu Taoshuai , xu shijun , Huang Zhuhui , Li Yang , Dong Ran
Published: February 2021

Background and aim of the study: Elderly patients are more likely to
have adverse complications after coronary artery bypass grafting (CABG).
There are few studies on the risk factors for acute kidney injury (AKI)
after surgery in elderly patients, especially in the Asian population.
This study retrospectively analysed the risk factors for AKI in Chinese
elderly patients after CABG and established a risk prediction model to
detect these risk factors early and take active intervention measures.
Methods: A total of 432 patients were included in this study from 2018
to 2019. AKI was defined according to the Kidney Disease Improving
Global Outcomes (KDIGO) criteria. The patients were divided into an AKI
group and a non-AKI group. Multivariate logistic regression analysis was
used to screen out the factors with p < 0.05. Results: Out of
432 patients in the study, 119 (27.5%) developed AKI. The estimated
glomerular filtration rate (eGFR), ≥3 coronary anastomoses, preoperative
intra-aortic balloon pump (IABP) implantation and prolonged ventilation
time were independent risk factors for AKI. The area under the ROC curve
was 0.702 (95% confidence interval (CI) [0.643-0.761], p
< 0.001). Conclusions: The eGFR, ≥3 coronary anastomoses,
preoperative IABP implantation and prolonged ventilation time are
independent risk factors for AKI in elderly patients undergoing coronary
artery bypass grafting. Early discovery of these risk factors and the
implementation of appropriate intervention measures are useful to reduce
the occurrence of AKI after CABG and improve the prognosis of patients.
Double-layered purse string uterine suture employing the French ambulatory cesarean section technique compared with single-layer continuous uterine suture: An ultrasound evaluation randomized trial.
Authors: dimassi kaouther , ami olivier , merrai rania , velemir luka , simon benedicte , fauck denis , triki amel
Published: February 2021

Objective: To test the hypothesis that compared to single layer
continuous uterine suture (SLCUS), a double layered purse string uterine
suture (PSUS) significantly reduces cesarean scar defect (CSD) rates,
without increasing the perioperative maternal morbidity. Design :
Interventional prospective, randomized study . Setting: University
obstetric units in Tunisia. Population: 100 pregnant women with an
indication of a planned Caesarean. Methods: Patients were enrolled in 2
groups according to the uterine suture technique: SLCUS or PSUS. A
Saline infusion hysterosonography was performed by the same senior
obstetrician blinded to the uterine suture technique 6 months after
surgery . Main Outcome measures: Operative time and Calculated blood
loss (CBL) were used for the short time analysis . Uterine and CSD
measurements were used for the mid time analysis . Results : Despite a
few minutes longer operative time in SUS group (7.17 ± 2.31 min Vs. 6.31
± 3.04 min, p = 0.028 in SLCUS group; p <10‾³); there was no
significant difference in terms of CBL (520 ± 58 in SUS group vs. 536 ±
50 ml in SLCUS group, p = 0.724). The medium-term analysis showed a
significant decrease in the rate of CSD with the PSUS: 6.66% vs.40%
with SLUCS; p = 0.002. Moreover, SLUCS was the leading risk factor for
CSD : adjusted OR=6 ;95% CI [0- 1],p < 10‾³) . Conclusion
: Compared to single layer continuous suture, purse string uterine
suture significantly reduces cesarean scar defect rates, without
increasing the perioperative maternal morbidity. NCT03930134.
https://clinicaltrials.gov/ct2/show/NCT03930134
Posterior reversible encephalopathy syndrome and spinal extradural hematoma in an elderly patient
Authors: Onishi Kouhei , Uchida Susumu , Fudaba Hirotaka , Kawasaki Yukari , Morishige Masaki , Fujiki Minoru
Published: February 2021

Posterior reversible encephalopathy syndrome (PRES) is identified on
magnetic resonance imaging by posterior predominant white and gray
matter lesions. PRES secondary to spinal disease is very rare. We report
a case of clinical and imaging findings about PRES associated with
spinal epidural hematoma.
Case study of a sudden loss of vision in a diabetic patient: an unusual cause. Endogenous Klebsiella pneumoniae panophthalmitis and cerebellar abscess associated with pyogenic liver abscess
Authors: Sharma Rohit , Sardar Sundus , Rozi Waail , Khamees Ibrahim Sa'id , Obeidat Ibrahim Mohammad , Ibrahim Wanis Hamad
Published: February 2021

Background: Community-acquired pyogenic liver abscesses due to
Klebsiella pneumoniae is increasingly recognized across the world
with more incidence in East Asian countries. Cases of endogenous
endophthalmitis secondary to pyogenic liver abscesses with K1 serotype
K. pneumoniae have been reported in the literature. We report a
case of endogenous panophthalmitis along with cerebellar abscess
occurring in a newly diagnosed diabetic patient secondary to pyogenic
liver abscess. Case presentation: A middle-aged male of east Asian
descent presented with sudden onset right eye vision loss associated
with fever. Workup revealed newly diagnosed diabetes mellitus,
panophthalmitis, cerebellar abscess, and pyogenic liver abscess due to
K. pneumoniae. The patient, unfortunately, underwent right eye
evisceration. Conclusion: Endogenous panophthalmitis due to K.
pneumoniae is a fatal complication and can result in blindness.
Multiple foci of infection can be present in such cases. Thorough
workup, prompt antibiotics as well as surgical treatment may improve
prognosis.
Incorporating genotyping to identify patients with G6PD deficiency
Authors: Morris Sarah , Crews Kristine , Hayden Randall , Takemoto Clifford , Yang Wenjian , Baker Donald , Broeckel Ulrich , Relling Mary , Haidar Cyrine
Published: February 2021

Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a
common X-linked enzyme disorder associated with hemolytic anemia after
exposure to certain medications or foods. Activity testing is the gold
standard for detecting G6PD deficiency; however, this test is affected
by various hematologic parameters. Clinical G6PD genotyping is included
in pharmacogenetic arrays and clinical sequencing and may be reconciled
with activity results. Methods: Patients (n=1,391) enrolled on an
institutional pharmacogenetic testing protocol underwent clinical G6PD
genotyping for 164 G6PD variants. For the 446 patients with G6PD
activity results, algorithms were designed to assign G6PD status,
accounting for known interferences with the activity assay and for G6PD
genotype results. We developed clinical decision support alerts to
inform prescribers when high-risk medications were prescribed, warning
of gene-drug interactions and recommending therapy alteration. Results:
Of 1,391 patients with genotype, 1,334 (95.9%) patients were predicted
to have normal G6PD activity, 30 (2.1%) were predicted to have variable
G6PD activity, and 27 (2%) were predicted to have deficient G6PD
activity. Of the 417 patients with a normal genotype and an activity
result, 415 (99.5%) had a concordant normal G6PD phenotype. Of the 21
patients with a deficient genotype and an activity result, 18 (85.7%)
had a concordant deficient activity result. Genotyping reassigned
phenotype in 5 patients with discordant genotype and activity results: 3
switched from normal to deficient, and 2 switched from deficient to
normal. Conclusion: G6PD activity and genotyping are two independent
testing methods which can be used in conjunction to assign a more
informed G6PD phenotype.
Comparison of Transcutaneous Tibial Nerve Stimulation (TTNS) Protocols for Women With Refractory Overactive Bladder (OAB), a Prospective Randomised Trial
Authors: ALKIŞ Okan , Sevim Mehmet , Kartal Ibrahim , Baser Aykut , Ivelik Halil , Aras Bekir
Published: February 2021

Objectives: Transcutaneous Tibial Nerve Stimulation (TTNS) is a
non-invasive method used in OAB treatment. We aimed to compare the
effectiveness of the once a week and three times a week TTNS procedure
in women diagnosed with wet type refractory OAB. Methods: A total of 60
patients diagnosed with wet type OAB was refractory to medical treatment
included in the study. Participants were equally and randomly divided
into two groups: TTNS treatment was performed with a time duration of 30
minutes for 12 weeks, once a week to Groıp-I and three times a week to
Group-II. Pre and post-treatment OAB-V8/ICIQ-SF scores and voiding
frequencies recorded in the bladder diary were compared between groups.
Results: Four patients in Group-1 and eight in Group-2 left the study
without completing the treatment. TTNS was performed in both groups for
12 weeks. There was a significant decrease in the voiding frequency,
OAB-V8, ICIQ-SF scores in both group-1 and group-2 (p<0.001).
A significant decrease in the OAB-V8 score was observed in the 5th week
in Group-1, and on the 3rd week in group-2. Complete response was
observed in 6 patients (23.1%) in Group-1 after 12 weeks of TTNS
procedure. In group-2, 10 patients (45.5%) had a complete response.
After the 12-week TTNS procedure, no significant difference was observed
between the groups in terms of treatment response. Conclusion: TTNS can
be safely used before invasive treatments in resistant OAB. TTNS
procedure three times a week seems more effective than performing it
once a week.
Application of dichroic glass in the architectural design of buildings
Authors: Petrovic Vladana , Stoiljkovic Branislava , Zivkovic Milica , Petkovic-Grozdanovic Natasa , Medenica Milena
Published: February 2021

The application of coloured and optical glass in architecture is of great
importance in terms of creating spatial dynamics and uniqueness of space.
Dichroic glass is a type of glass coated with a thin layer of metal, which
causes the glass surface to change in colour depending on the viewing angle.
The colour of the glass depends on the incidence of different wavelengths of
light passing through or bouncing off the glass surface, thus creating
different effects of colour refraction. Created effects provide different
possibilities in the design of buildings and improvements in the aesthetic
quality of the interior space. This paper deals with the analysis and
application of coloured dichroic glass in architecture and interior design.
Pirina Modifiyeli Bitümlerin Yüksek Sıcaklıklardaki İşlenebilirliği ve Kalıcı Deformasyon Direnci
Authors: GEÇKİL Tacettin , İNCE Ceren Beyza , İSSİ Semih
Published: February 2021

Bu çalışmada, tarımsal bir atık olan pirina’nın bitümlü bağlayıcıların yüksek sıcaklıklardaki işlenebilirliği ve kalıcı deformasyon direnci üzerindeki etkisi araştırılmıştır. Bu amaçla, ilk olarak saf B 160/220 bitüme ağırlıkça %5, 10, 15 ve 20 oranlarında pirina eklenerek modifiye bitümler elde edilmiştir. Saf ve modifiye bitümlerin fiziksel karakteristikleri penetrasyon, yumuşama noktası ve düktilite deneyleri ile; yüksek sıcaklıklardaki akışkanlık ve işlenebilirlik özellikleri dönel viskozimetre (RV) deneyi ile; bağlayıcıların kalıcı deformasyon dirençleri dinamik kayma reometresi (DSR) deneyi ile; kimyasal karakterizasyonları ise taramalı elektron mikroskopu (SEM) ve X-ışını kırınımı (XRD) analizleri ile belirlenmiştir. Fiziksel ve RV deney sonuçlarına göre, pirina katkısı ile bağlayıcıların sertleşme eğilimi gösterdiği, akışkanlıklarının azaldığı ve buna bağlı olarak işlenebilirlik sıcaklıklarının arttığı görülmüştür. Ayrıca, bağlayıcıların sıcaklık hassasiyetlerinin de pirina katkısı ile azaldığı tespit edilmiştir. DSR deney sonuçlarına göre, saf bitümün 58 oC yüksek sıcaklıkta kalıcı deformasyonlara karşı göstermiş olduğu direnç, pirina katkı artışına bağlı olarak özellikle %15 oranında 64oC sıcaklığa yükselmiştir. Kimyasal karakterizasyon sonuçlarına göre, bitüm-pirina karışımının homojen tek fazlı bir yapı oluşturduğu ve ham pirinanın selülozik yapısı sebebiyle karışımın sertleşmesine rağmen elastik bir yapı haline geldiği görülmüştür. Sonuç olarak, pirina katkısı ile bağlayıcıların sertleşerek işlenebilirliklerinin azaldığı ancak yüksek sıcaklıklardaki kalıcı deformasyon dirençlerinin arttığı görülmüştür.
Reporting of gestational diabetes and other maternal medical conditions
Authors: Baldwin Heather J , Nippita Tanya A , Rickard Kristen , Torvaldsen Siranda , McGee Therese M , Patterson Jillian A
Published: February 2021

IntroductionHospital datasets are a valuable resource for examining prevalence and outcomes of medical conditions during pregnancy. To enable effective research and health planning, it is important to determine whether variables are reliably captured.
ObjectiveTo examine the reliability of reporting of gestational and pre-existing diabetes, hypertension, thyroid conditions, and morbid obesity in coded hospital records that inform the population-level New South Wales Admitted Patient Data Collection.
MethodsCoded hospital admission data from two large tertiary hospitals in New South Wales, from 2011 to 2015, were compared with obstetric data, collected by midwives at outpatient pregnancy booking and in hospital after birth, as the reference standard. Records were deterministically linked and sensitivity, specificity, positive predictive values and negative predictive values for the conditions of interest were obtained.
ResultsThere were 36,051 births included in the analysis. Sensitivity was high for gestational diabetes (83.6%, 95% CI 82.4–84.7%), pre-existing diabetes (88.2%, 95% CI 84.1–91.6%), and gestational hypertension (80.1%, 95% CI 78.2–81.9%), moderate for chronic hypertension (53.5%, 95% CI 47.8–59.1%), and low for thyroid conditions (12.9%, 95% CI 11.7–14.2%) and morbid obesity (9.8%, 95% CI 7.6–12.4%). Specificity was high for all conditions (≥97.8%, 95% CI 97.7–98.0) and positive predictive value ranged from 53.2% for chronic hypertension (95% CI 47.5–58.8%) to 92.7% for gestational diabetes (95% CI 91.8–93.5%).
ConclusionOur findings suggest that coded hospital data are a reliable source of information for gestational and pre-existing diabetes and gestational hypertension. Chronic hypertension is less consistently reported, which may be remedied by grouping hypertension types. Data on thyroid conditions and morbid obesity should be used with caution, and if possible, other sources of data for those conditions should be sought.
Maxwell fluid flow in system supplying hydrodynamically active polymer to boundary layer of streamlined object
Authors:   Ivano-Frankivsk National Technical University of Oil and Gas, Pogrebnyak V. G. , Pogrebnyak A. V. ,   University of Customs and Finance, Perkun I. V. ,   Ivano-Frankivsk National Technical University of Oil and Gas
Published: February 2021

The article presents the results of the numerical simulation of the Maxwell fluid flow in the system supplying hydrodynamically active polymer in the boundary layer of a streamlined object. The case of slow flow is considered. In this case, the inertial terms can be neglected, the velocities, stresses, and stream functions can be written as the decomposition by Weisenberg number, and we can assume that the Weissenberg number is less than one. The established features of the behaviour of the Maxwell fluid flow with a longitudinal velocity gradient and the manifestation of the effects of elastic deformations are crucial for understanding processes taking place in the system supplying hydrodynamically active polymer in the boundary layer of a streamlined object. Understanding the nature of the effects of elastic deformations in the supplying system makes it possible to offer a hydrodynamic calculation of the modes of polymer solution injection into the boundary layer without any negative manifestations of the effects of the elastic deformations. The results of the numerical simulation confirmed the conception on the deformation-stress state of macromolecules (fluid elements) in polymer solution converging flow, based on the data previously obtained from experimental decisions concerning the hydrodynamic field structure in the input area of a slot and other openings.
Prototype of Control and Monitor System with Fuzzy Logic Method for Smart Greenhouse
Authors: Kurniawan Didik , Witanti Arita
Published: February 2021

To increase plant productivity, greenhouse buildings are needed that can protect plants from external factors and integrated with smart systems that can be monitored anytime and anywhere, and can provide optimal plant needs automatically. In this research, a system was built that can monitor greenhouse conditions in real time anywhere through Blynk application with IoT concept, as well as a system that can control output automatically with fuzzy logic method. The focus of control on this research is the duration of watering with Mini Water Pump and light intensity setting with LED Strip. This system is also equipped with FAN that can be active when the temperature is 31°C or more. Parameters used in this system are DHT22 sensor (air temperature and humidity), Soil Moisture sensor, Water Level sensor ,LDR sensor (light intensity) and RTC DS3231 (Real Time Clock), which is controlled with Arduino Mega 2560 microcontroller. In the test results obtained accuracy on fuzzy logic water pump by 93.1% and accuracy on fuzzy logic LED Strip by 99.6%. In the test results of the existing parameters, the results get a fairly optimal reading.
PERANCANGAN APLIKASI QUESTION ANSWERING SYSTEM PADA TERJEMAHAN ALQURAN
Authors: Khusna Arfiani Nur , Mardhia Murein Miksa
Published: February 2021

Al quran merupakan tuntunan bagi umat Islam. Suatu permasalahan tidak hanya mengacu pada satu ayat ataupun satu surat sehingga dibutuhkan waktu yang lama dalam proses pencarian secara manual, mengingat banyaknya jumlah ayat dan surat yang terkandung dalam Al quran. Berdasarkan hasil kuisioner yang dibagikan kepada 50 responden, terdapat 75% responden tidak dapat atau kesulitan dalam mencari jawaban terhadap makna atau masalah yang didasarkan pada terjemahan Al quran. Question answering system adalah sistem yang mengijinkan user menyatakan kebutuhan informasinya dalam bentuk natural language question (pertanyaan dalam bahasa alami), dan mengembalikan kutipan teks singkat atau bahkan frase sebagai jawaban. Penelitian ini merancang aplikasi question answering system pada terjemahan al quran untuk membantu pengguna menemukan jawaban terjemahan Al quran dengan menggunakan pertanyaan yaitu dimana, apa, siapa, berapa, kapan dan mengapa. Berdasarkan hasil pengujian rancangan aplikasi diperoleh nilai usability 28 dari 35 yang menunjukkan bahwa rancangan aplikasi layak dikembangkan sebagai alat bantu dalam mencari jawaban terjemahan Al quran dan sesuai kebutuhan pengguna.
PENGEMBANGAN APLIKASI QnA UNTUK PENDAFTARAN MAHASISWA BARU STMIK AKAKOM
Authors: Nugroho Muhammad Agung , Damayanti Ariesta , Rifai Muhammad Fahrur , Windarti Syamsu
Published: February 2021

STMIK AKAKOM annually opens new student registration through offline and online media. Through online media, several media such as websites, social media and email are used. However, on media such as social media, there are questions that often arise regarding new student registration information. With limited human resources to always be online for 24 hours, an alternative model is needed to provide answers to these questions, even though the social media manager offline. Nowadays. In the term of technological developments, it is possible to create a model of knowledge base in the form of a summary of questions and answers to certain topics. This knowledge base can use as a model for creating a prototype application that can provide answers if there are questions related to new student registration. This study aims to provide convenience in the question and answer process by using a Google Dialogflow.
Efektifitas Penyaluran Alokasi Dana Desa Pada Empat Desa Di Kabupaten Bojonegoro
Authors: Suhartono Edy , Mustofa M.
Published: February 2021

Penelitian ini bertujuan mencari bagaimana cara menilai efektifitas penyaluran Alokasi Dana Desa dari pemerintah Kabupaten Bojonegoro kepada pemerintah Desa. Data yang digunakan dalam penelitian ini adalah data sekunder yang berasal dari Badan Pusat Statistik (BPS) Kabupaten Bojonegoro, Data Alokasi Dana Desa dari Badan Pemberdayaan Masyarakat dan Pembangunan Desa (BPMPD) Kabupaten Bojonegoro, serta Data Monografi Desa, ada empat desa dari berbagai kecamatan di wilayah Bojonegoro. Hasil penelitian ini menunjukkan bahwa penyaluran Alokasi Dana Desa di empat desa tersebut belum mencapai efektifitas yang optimal. Hal tersebut dapat dilihat dari masih adanya kesenjangan (disparitas) pembangunan ekonomi antar wilayah kecamatan dan cenderung memiliki  nilai Indeks Williamson dari tahun 2014 hingga tahun 2018 mendekati nilai 1 (satu). Melalui analisa Klassn Typology dapat diketahui bahwa hasil dari pembangunan ekonomi selama tahun 2014 hingga tahun 2018, dari 28 kecamatan di Kabupaten Bojonegoro, Jawa Timur hanya beberapa daerah yang termasuk dalam kategori daerah cepat maju dan cepat tumbuh.
Kebijakan Pemerintah Kabupaten Halmahera Timur Dalam Menanggulangi Masalah Stunting
Authors: Ridua Iren Ressie , Djurubassa Gloria M. P
Published: February 2021

Penelitian ini membahas tentang masalah stunting di Kabupaten Halmahera Timur dan bagaimana upaya penanggulangannya. Stunting merupakan bentuk gagal tumbuh kembang pada balita yang menyebabkan gangguan pertumbuhan linear, akibat dari ketidakcukupan nutrisi yang berlangsung lama, mulai dari masa kehamilan sampai usia 24 bulan. Metode penelitian  menggunakan metode deskriptif kualitatif. Hasil penelitian menunjukkan bahwa upaya penanggulangan masalah stunting di Kabupaten Halmahera Timur khususnya di Kecamatan Maba Utara sudah dilaksanakan namun belum sepenuhnya baik karena kurangnya sosialisasi dari Dinas Terkait mengenai permasalahan dan upaya penanganannya. Pentingnya peran aktif  dan kerja sama yang baik antara pemerintah daerah dan tenaga kesehatan yakni puskesmas dan kader posyandu untuk bekerja sama mengatasi persoalan stunting. Kebijakan penangunggulangan stunting yang di lakukan antara lain pemberian makanan tambahan (PMT) pada balita dan ibu hamil dan melakukan posyandu. Perlu adanya advokasi dan sosialisasi tentang stunting agar masyarakat mampu menerapkan pola makan gizi seimbang dan mendapatkan pelayanan yang layak untuk meningkatkan kesejahteraanya.
Ugensi Database ASN: Potret Tata Kelola Pangkalan Data Kepegawaian Pemerintah Kota Yogyakarta Dan Kota Banjarbaru
Authors: Syah Robby Firman , Rachman Nisa Agistiani
Published: February 2021

Salah satu tantangan dan aspek penting dalam mendukung pelaksanaan manajemen ASN adalah tersedianya pangkalan data kepegawaian yang komprehensif dan terintegrasi. Namun masih terdapat kendala dalam pembangunan dan arah pengembangan yang belum terkelola secara optimal. Tulisan ini membahas tata kelola pangkalan data kepegawaian di 2 (dua) pemerintah daerah yaitu Pemerintah Kota Yogyakarta dan Pemerintah Kota Banjarbaru. Tujuannya ialah sebagai studi awal melihat tata kelola pangkalan data kepegawaian pemerintah daerah dalam kepentingannya mendukung pembangunan database ASN secara nasional. Penelitian dilaksanakan di Badan Kepegawaian Pendidikan dan Pelatihan Kota Yogyakarta dan Kota Banjarbaru. Dengan menggunakan studi dokumen dan wawancara terhadap subjek penelitian yang membidangi urusan kepegawaian di pemerintah daerah, hasil penelitian menunjukkan: pertama, pemerintah daerah telah melakukan start dan inisiasi pada digitalisasi data dan layanan kepegawaian, walaupun pada praktiknya memiliki desain dan komposisi fitur yang berbeda; kedua, pangkalan data kepegawaian yang dikembangkan pemerintah daerah mencapai derajat kualitas pengembangan yang berbeda.
Pengaruh Politik Uang Terhadap Partisipasi Pemilih Pemilukada Pemilihan Bupati dan Wakil Bupati Wajo Tahun 2018
Authors: Hawing Hardianto , Fadillah Besse Nurul , Parawu Hafiz Elfiansya
Published: February 2021

Penelitian ini bertujuan untuk mengetahui Politik Uang dan Partisipasi Pemilih Pemula pada Pemilihan Bupati dan Wakil Bupati Wajo tahun 2018. Jenis penelitian menggunakan pendekatan kuantitatif. Data yang diolah hasil penyebaran instrumen berupa kusioner terhadap 98 responden yang menjadi sampel penelitian dengan menggunakan teknik purposive sampling. Data yang diperoleh, kemudian dianalisis menggunakan analisis regresi linier sederhana secara parsail dan simultan. Hasil penelitian analisis deskriktif menujukkan bahwa variabel politik uang (X) berdasarkan indicator pemberian uang, pemberian barang, pemberian janji/iming-iming masuk dalam kategori cukup berpengaruh dengan rata-rata skor 2,89 dan variabel partisipasi politik (Y)  berdasarkan indikator memberikan suara, menghadiri rapat umum, menjadi anggota suatu partai/ kelompok kepentingan, mengadakan hubungan kontak dengan pemerintah/anggota parlemen masuk dalam kategori cukup berpengaruh dengan rata-rata skor 2,78.  Berdasarkan hasil uji regresi linier sederhana menunjukkkan bahwa variabel politik uang berpengaruh sebesar 53% terhadap partisiapsi politik pada Pemilihan Bupati dan Wakil Bupati Tahun 2018.
The Universality of the Universal Declaration of Human Rights: Does it merely express Western Values?
Authors: Anam Syaiful
Published: February 2021

The debate over the universality of Universal Declaration of Human Rights remains taking place. Apart from the fact that the document remains popular and has been encouraged by many countries around the world. The debate revolves around values and cultural differences among countries claiming that Western values have been predominating the content of the declaration itself. This essay argues that the dispute towards the universality of UDHR would likely form a robust standard and values of internationally recognized human rights as long as a cross-cultural and cross-philosophical talk could be encouraged.
Kompleksitas Keamanan Kawasan dan Tantangan Kerja Sama Keamanan Asia Timur
Authors: Al Syahrin M. Najeri
Published: February 2021

This article will explain the regional security complex as a key challenge in the establishment of regional security cooperation in East Asia. The complex of security in East Asia described by explaining the security relations between North Korea and South Korea, China and Japan, the United States with Japan, and China with the United States and a pattern of chain reaction to the various security policies of these countries. This security complex makes it difficult to establish effective regional security cooperation. The Challenge of the regional security complex that most decisive in the formation of cooperation that will be done by the countries of the East Asia region is due to competition and differences of interests between the United States and China as a superpower state in the region. In addition, the many differences in the nature and orientation of political interests of Japan, South Korea, and North Korea are also still a constraint in the formation of regional security organizations and cooperation.
Narcoterrorism dan Perdagangan Senjata Ilegal sebagai Penghubung Jaringan Terorisme Internasional
Authors: Karjaya Lalu Putrwandi , Sood Mohammad , Safitri Purnami
Published: February 2021

The international terrorism usually has intercourse with the illegal trade to available funds them that group can survive. Various terrorist network generally has a very different ways with the others, so it was hard to figure relation between one and the other. Nevertheless, in a manner funding had then we can see how a terrorist network was in a continent can be connected with terrorists in other continents through this funding. Terrorist financing itself obtained from illegal trade like as drug trafficking and illegal weapons. Drug trafficking by terrorists is then called narcoterrorism where business assisted by user in the world. The user uses the links between terrorist networks on the continents.
Reconstructing Westphalian Sovereignty as an Effort to Enforce Human Rights Case Study: Humanitarian Intervention in the Libyan Conflict
Authors: Mubin Anna Kharisma Fehmita
Published: February 2021

State sovereignty and humanitarian intervention are two sides of a coin, presenting a threat to human rights enforcement, especially when human rights violation is done by the state. Failure from a state to provide human rights protection for its citizen will lead to intervention from the international community to enforce human rights in the name of humanitarian norms. The humanitarian intervention will indirectly weaken the principles of Westphalian state sovereignty as the main premise in the politics of international relations. This article is a case study of the Libyan conflict in 2011. This study uses the constructivism approach to analyze the contrasting relation between the principles of traditional Westphalian sovereignty and humanitarian intervention concept, and how this relationship may shift the human rights norms in the international community. In the constructivism approach, it is not enough to offer a causal explanation in order to understand international politics. Instead, it needs a more interpretative understanding. Hence, this study is conducted with a qualitative method, a critical approach to human rights in contemporary international politics.
Asian Insfastructure Investment Bank (AIIB) Sebagai Bentuk Hegemoni Baru Tiongkok
Authors: Fanny Cindy Rezma , Arifianti Dwi Nur , Augusta Erlandi Daffa
Published: February 2021

Since the rise of China as a 'great power' in the 1940s, China has continued to expand its economic power. His role which was felt to be insignificant in the world multilateral institutions or Bretton-Woods institutions made China initiate a new multilateral institution which was considered to have a bureaucracy that was easier than the Bretton-Woods institution. In addition, the financial condition of the World Bank which is considered inadequate for the Asian infrastructure development needs and the failure of America to host China so that the American allies want to join the AIIB make China more convinced by its decision to establish AIIB. AIIB initiated by President Xi Jinping and announced its establishment in 2014. In 2015, 57 founding countries officially signed the Article of Agreement (AOA) as the basis for the formation of the AIIB. In this study, the researcher will explain the motivations behind the formation of the AIIB. This research explained through a quantitative descriptive method so that the researcher will explain the purpose of establishing AIIB in detail. As a result, by analyzing through the perspective of Dependency Theory, the dependence of third world countries on the AIIB would indirectly bring about hegemony from China.
Kontradiksi Demokrasi Liberal dan “Akhir Sejarah” Yang Tertunda
Authors: Karina Eva Novi
Published: February 2021

Due to historical developments and the works of theorists such as Francis Fukuyama, predominant political-economic literature has claimed that the combination of a “free market economy” and “liberal democracy built on equal rights” results in the most developed form of human society. With economic and political liberalism, societies of Western Europe and North America “at the vanguard of civilization” considered have reached the endpoint of humankind’s ideological evolution hence Western liberal democracy has been perceived as the final form of human government. However, the current rising wave of right-wing populism along with the exercise of protectionist economic measures in the most developed democratic countries has shown that democracy has begun to malfunction. Depart from this point, this article aims to re-examine the relationship between free market and democracy, and analyses the real inequalities manifested in income and the ownership of the means of production, and the inequalities within capitals, and between capital and wage labor. It concludes that the logic of market mechanisms poses a threat to democracy, while the extension of democracy would inevitably limit the freedom of the market and curb capital accumulation.
Perbandingan Sistem Pinjaman IMF dan BRICS New Development Bank serta Potensi Dominasi Sistem Moneter Internasional
Authors: Pamungkas Mahendra Lantang , Rahayu Riswanti Dyah Sekar , Krisyanti Trieska Ayu
Published: February 2021

America is the dominant power for a long time since the World War and gave many aid for many state developments in the world with their ‘Marshall Plan’ policy. America domination clarified by the existence World Trade Organization. United States of America legitimation not only limited to WTO, there are several international economic organizations such as World Bank and International Monetary Fund where the America hold an important power. Countries that want to compete with America legitimacy establish an organization called BRICS. BRICS consist of Brazil, Russia Federation, India, China, and South Africa. BRICS created a bank called BRICS NDB or National Development bank to compete IMF domination. This research will explain the differentiation between IMF and NDB, alongside with how NDB have capability to compete IMF as an international bank that give loans to countries. This research uses descriptive comparative method, so this research will have focused on comparation between the two banks. Analysis on this research will use Structural Power Theory with Middle Power concept to explain IMF domination and how NDB that created by Middle Powered countries can replace IMF domination.
The Matter of Quebec Movement: A Review on Canadian Domestic Politics
Authors: Al-hasin FIkry Muhammad Reza , Kusumaningrum Demeiati Nur
Published: February 2021

The Canadian government has succeeded to maintain its political stability by implementing middle-ways approach to face the separatism movement. Parti Quebecois has been the biggest promoter of Quebec sovereign movement. This political party has held referendums to be independent from the central government and managed to gain public attention. This paper aimed to figure out how the series of Quebec sovereign movements affected Canadian domestic politics. It used constructivist approach to explain why the Quebec struggle for independent and how its strategies influence the Canadian domestic structure. The data obtained from library research. This paper examines the effort of Quebec movement consist of  (1) creating a political discourse of “self-determinantion”. The social movement transforms into Québécois political party and it visioned to gain territory of the province since the decade of the 1960s; (2) social construction dealing with the issue of French identity as non-Canadian culture. The supports of the idea embedded in the several forms of regulations and propaganda in the public sphere.
The Challenge of Training Translators and Interpreters in the Social Context of Foreign Unaccompanied Minors
Authors: Saleh Hussein Hanan
Published: February 2021

There are many challenges facing teachers in the classroom, throughout the process of training translators and interpreters in higher education. This paper aims to share reflections and teaching practices related to the preparation of these future professionals, in the context of caring for a vulnerable group of the immigrant community, Unaccompanied Foreign Minors (UFM). The proposal is based on taking a step further in the Teaching Practice and Development (TPD) methodology of Specialized Translation and Bilateral Interpreting subjects by incorporating new knowledge such as that related to Public Management or Social Sciences. This is due to the firm belief of the author of this manuscript in the quality of training from a multidisciplinary approach that will undoubtedly bring many more benefits, not only to the students, but also to UFM as a sensitive group, to the Administration as a competent body and, also, to the host society.This proposal arises from a simple question: Are future translators and interpreters prepared to manage their work in a vulnerable context? To answer this question, it is necessary to analyze the practical knowledge acquired by these professionals in the preparation phase. Thus, the main objective of this work is to demonstrate that the use of real texts in the Translation and Interpreting classroom is a bet that leads to an excellent academic training. Furthermore, this multidisciplinary work will serve as a model to be followed by teachers in this field
Sistem Manajemen Persediaan pada Bunda Bakery dengan Mengimplementasikan Material Requirement Planning (MRP)
Authors: Fitri Aisyah , Muslim Istianah
Published: February 2021

Bunda Bakery merupakan bakery yang telah beroperasi sejak tahun 2017. Bunda Bakery memproduksi rotinya berdasarkan asumsi pemiliknya dan menyebabkan proses produksi yang tidak teratur. Sering terjadi overproduksi sehingga roti yang dihasilkan tidak layak untuk dijual. Hal ini juga mempengaruhi jumlah persediaan bahan baku yang tidak terkendali. Oleh karena itu diperlukan suatu sistem yang dapat membantu dalam pengendalian pasokan bahan baku dengan menggunakan teknik perhitungan Material Requirement Planning (MRP). Implementasi MRP juga didukung dengan menggunakan metode peramalan Single Exponential Smoothing dan metode Lot Sizing Fixed Order Quantity. Berdasarkan hasil pengujian yang dilakukan terhadap sistem informasi yang dibangun dengan menggunakan pengujian blackbox didapatkan bahwa 100% fungsionalitas sistem berjalan dengan baik. Pengujian penerimaan pengguna (UAT) yang dilakukan menunjukkan bahwa sistem yang dibangun dapat diterima oleh pengguna. Selanjutnya pengujian perbandingan akurasi metode menunjukkan bahwa hasil perhitungan yang ditampilkan pada sistem sudah akurat. Dan pengujian terakhir adalah uji usability, hasil pengujian menunjukkan rata-rata 89.95% pengguna sangat setuju dengan pembangunan sistem ini.
Analisis Kualitas Ikan Bada Terbaik Menggunakan Metode Simple Additive Weighting
Authors: Trisna Novi , Jamhur Annisak Izzaty , Prawiro Radius
Published: February 2021

Mandeh area of the south coast of west Sumatra there are many business units selling bada fish. The business unit uses the invisible way of distinguishing good ikan bada for sale, in that way many customers complain because there are still many bada ikan that are not good mixed when purchased by customers. To solve it using a decision support system with a simple additive Weighting (SAW) method, this SAW method looks for Weighting summation of performance ratings of various alternatives that can be distinguished from several criteria. In determining good quality bada ikan then the criteria are distinguished into 5 criteria in terms of color, texture, taste, shape and smell.
Implementasi Algoritma Luc Pada Aplikasi Keamanan Short Message Service (SMS) Berbasis Android
Authors: Anshori Yusuf , Nugraha Deny Wiria , Pratomo Arief
Published: February 2021

Short Message Service (SMS) still has security problems with attempts to steal messages, intercept messages, hijack messages by parties who are not responsible for obtaining information. Cryptography is the science of maintaining the confidentiality of information from aspects that can threaten information security with certain mathematical algorithms and techniques. The Luc algorithm is a public key cryptographic algorithm that was developed using the lucas function. This study aims to implement the Luc algorithm on an Android-based SMS security application in the National Narcotics Agency of Central Sulawesi Province to maintain privacy in communication between the sender and recipient of the message. This application was created using an Android studio developer with the Java programming language. Based on the results of the first test for a sample of plain messages in the word KOTA PALU that uses public key 13 produces the message cipher P=Se!CQa. The second test result for the message sample on the word KOTA PALU that uses public key 29 generates the AD*`_$(NQ cipher message