bluuebunny/crossref_metadata_2025 huggingface dataset:
Cost structure in specialist mental healthcare: what are the main drivers of the most expensive episodes?
Authors: Ki Yeujin , McAleavey Andrew Athan , Moger Tron Anders , Moltu Christian
Published: November 2023

Background

Mental disorders are one of the costliest conditions to treat in Norway, and research into the costs of specialist mental healthcare are needed. The purpose of this article is to present a cost structure and to investigate the variables that have the greatest impact on high-cost episodes.

Methods

Patient-level cost data and clinic information during 2018–2021 were analyzed (N = 180,220). Cost structure was examined using two accounting approaches. A generalized linear model was used to explain major cost drivers of the 1%, 5%, and 10% most expensive episodes, adjusting for patients’ demographic characteristics [gender, age], clinical factors [length of stay (LOS), admission type, care type, diagnosis], and administrative information [number of planned consultations, first hospital visits, interval between two hospital episode].

Results

One percent of episodes utilized 57% of total resources. Labor costs accounted for 87% of total costs. The more expensive an episode was, the greater the ratio of the inpatient (ward) cost was. Among the top-10%, 5%, and 1% most expensive groups, ward costs accounted for, respectively, 89%, 93%, and 99% of the total cost, whereas the overall average was 67%. Longer LOS, ambulatory services, surgical interventions, organic disorders, and schizophrenia were identified as the major cost drivers of the total cost, in general. In particular, LOS, ambulatory services, and schizophrenia were the factors that increased costs in expensive subgroups. The “first hospital visit” and “a very short hospital re-visit” were associated with a cost increase, whereas “the number of planned consultations” was associated with a cost decrease.

Conclusions

The specialist mental healthcare division has a unique cost structure. Given that resources are utilized intensively at the early stage of care, improving the initial flow of hospital care can contribute to efficient resource utilization. Our study found empirical evidence that planned outpatient consultations may be associated with a reduced health care burden in the long-term.
Evaluating the implementation of Nuevo Amanecer-II in rural community settings using mixed methods and equity frameworks
Authors: Santoyo-Olsson Jasmine , Stewart Anita L. , Ortiz Carmen , Palomino Helen , Torres-Nguyen Alma , Coleman LaVerne , Alhomsi Alia , Quintero Stephanie , Bonilla Jackie , Santana-Ufret Veronica , Nápoles Anna María
Published: November 2023

Background

The 10-week Nuevo Amanecer-II intervention, tested through a randomized controlled trial, reduced anxiety and improved stress management skills among Spanish-speaking Latina breast cancer survivors. This paper describes the implementation and equity evaluation outcomes of the Nuevo Amanecer-II intervention delivered in three California rural communities.

Methods

Using implementation and equity frameworks, concurrent convergent mixed methods were applied to evaluate implementation (feasibility, fidelity, acceptability, adoption, appropriateness, and sustainability) and equity (shared power and capacity building) outcomes. Quantitative data were collected using tracking forms, fidelity rating forms, and program evaluation surveys; qualitative data were collected using semi-structured in-depth interviews. Respondents included community-based organization (CBO) administrators, recruiters, compañeras (interventionists), and program participants.

Results

Of 76 women randomized to the intervention, 65 (86%) completed at least 7 of 10 sessions. Participants’ knowledge (85% correct of 7 questions) and skills mastery were high (85% able to correctly perform 14 skills). Mean fidelity ratings across compañeras ranged from 3.8 (modeled skills) to 5.0 (used supportive/caring communication); 1–5 scale. The program was rated as very good/excellent by 90% of participants. Participants and compañeras suggested including family members; compañeras suggested expanding content on managing thoughts and mood and healthy living and having access to participant’s survivorship care plan to tailor breast cancer information. CBOs adopted the program because it aligned with their priority populations and mission. Building on CBOs’ knowledge, resources, and infrastructure, implementation success was due to shared power, learning, responsibility, and co-ownership, resulting in a co-created tailored program for community and organizational contexts. Building intervention capacity prior to implementation, providing funding, and ongoing technical support to CBOs were vital for fidelity and enhancement of recruiter and compañera professional skills. Two of three CBOs created plans for program sustainability beyond the clinical trial; all administrators discussed the need for new funding sources to sustain the program as delivered.

Conclusions

Building on community assets and using equitable participatory research processes were central to the successful implementation of a peer-delivered psychosocial intervention in three rural communities among Spanish-speaking Latinas with breast cancer.
Kaempferol prevents aseptic loosening via enhance the Wnt/β-catenin signaling pathway in vitro and in vivo
Authors: Qiu Wenkui , Li Zhenghui , Su Zhenyan , Cao Lichao , Li Lei , Chen Xi , Zhang Wanhong , Li Yanqing
Published: November 2023

Kaempferol has demonstrated notable positive effects on the osteogenic differentiation of mesenchymal stem cells (MSC) and osteoblasts. A substantial body of research has emphasized the role of dislodged titanium particles in aseptic loosening following joint replacement surgery. This study predominantly investigates the suppressive influence of Kaempferol on osteolysis induced by titanium (Ti) alloy particles. In vitro investigations disclosed that Kaempferol effectively enhanced mineralization and alkaline phosphatase (ALP) activity in bone-marrow mesenchymal stem cells exposed to Ti particles. In addition, we conducted a comprehensive analysis of osteogenic differentiation microarray data_sets (GSE37676, GSE79814, and GSE114474) to identify differentially expressed genes. Significantly, Kaempferol upregulated the expression of critical osteogenic markers, including Runt-related transcription factor 2 (Runx2), osteocalcin (OCN), osterix/Sp-7, and β-catenin. In vivo experiments, including H&E staining and Immunohistochemistry, provided compelling evidence that Kaempferol exerted a robust inhibitory effect on periprosthetic osteolysis in mice, with particularly pronounced results at higher doses. Moreover, it elevated the expression levels of osteogenic factors and Wnt/β-catenin signaling components. These findings collectively indicate that Kaempferol mitigates the hindrance to osteogenesis posed by titanium particles by activating the Runx2 and Wnt/β-catenin signaling pathways. This research lays a solid foundation for the prospective utilization of Kaempferol in the management of aseptic loosening following arthroplasty, offering promising therapeutic potential.
Clinician Perspectives Regarding the Impact of Information Technology on Multidisciplinary Tumor Boards: A National Comprehensive Cancer Network Survey
Authors: Arafat Waddah , Fu Paul , Wagner Andrew J. , Osterman Travis , Martin Daniel B. , Sugalski Jessica , Heinrichs Tricia , Racz Jennifer , Tevaarwerk Amye J.
Published: November 2023

PURPOSE

Multidisciplinary tumor boards (MTBs) support high-quality cancer care. Little is known about the impact of information technology (IT) tools on the operational and technical aspects of MTBs. The National Comprehensive Cancer Network EHR Oncology Advisory Group formed a workgroup to investigate the impact of IT tools such as EHRs and virtual conferencing on MTBs.

METHODS

The workgroup created a cross-sectional survey for oncology clinicians (eg, pathology, medical, surgical, radiation, etc) participating in MTBs at 31 National Comprehensive Cancer Network member institutions. A standard invitation e-mail was shared with each EHR Advisory Group Member with a hyperlink to the survey, and each member distributed the survey to MTB participants at their institution or identified the appropriate person at their institution to do so. The survey was open from February 26, 2022, to April 26, 2022. Descriptive statistics were applied in the analysis of responses, and a qualitative thematic analysis of open-ended responses was completed.

RESULTS

Individuals from 27 institutions participated. Almost all respondents (99%, n = 764 of 767) indicated that their MTBs had participants attending virtually. Most indicated increased attendance (69%, n = 514 of 741) after virtualization with the same or improved quality of discussion (75%, n = 557 of 741) compared with in-person MTBs. Several gaps between the current and ideal state emerged regarding EHR integration: 57% (n = 433 of 758) of respondents noted the importance of adding patients for MTB presentation via the EHR, but only 40% (n = 302 of 747) reported being able to do so most of the time. Similarly, 87% (n = 661 of 760) indicated the importance of documenting recommendations in the EHR, but only 53% (n = 394 of 746) reported this occurring routinely.

CONCLUSION

Major gaps include the lack of EHR integration for MTBs. Clinical workflows and EHR functionalities could be improved to further optimize EHRs for MTB management and documentation.
Olhar dos Estudos Organizacionais para se pensar a reforma das organizações policiais no Brasil
Authors: Alcadiapani Rafael , Matarazzo Rezende Gustavo , Vianna Fernando , Fernandes Alan , Sérgio de Lima Renato
Published: November 2023

Estudos acerca do campo organizacional da segurança pública tiveram início, no Brasil, nas Ciências Sociais, ainda nos anos 1980. O papel central das organizações policiais na sociedade contemporâneas e os estudos acerca das suas reformas têm necessitado de interações epistemológicas mais profícuas. Nesse sentido, entendemos que os Estudos Organizacionais podem contribuir para esse debate, especialmente no que tange quatro categorias fundamentais: tecnologia, uso da força, cultura e comportamento e grupos minoritários. Entendemos que, de um lado, a abordagem predominante nas Ciências Sociais segue uma visão das polícias como mero aparelho de repressão e violência estatal, enquanto, de outro lado, a produção interna das polícias segue uma abordagem totalmente instrumental e pouco reflexiva. Defendemos que os Estudos Organizacionais podem alinhar-se às abordagens reformistas e profissionalizantes da polícia em Ciências Sociais, oferecendo um caminho mais reflexivo para a produção de conhecimento interno das polícias, contribuindo, assim, para o aprimoramento das polícias brasileiras.
Συγκριτική μελέτη κβαντικών και κλασικών παιγνίων και συσχετισμός τους με μη συμβατικά μοντέλα υπολογισμού
Authors: Κασταμπολίδου Καλλιόπη
Published: November 2023

Στα πλαίσια της διδακτορικής έρευνας, γίνεται μια μελέτη κλασικών και κβαντικών παιγνίων και ο συσχετισμός αυτών με μη συμβατικά μοντέλα υπολογισμού. Η Θεωρία Παιγνίων μελετά καταστάσεις με τη μορφή παιχνιδιών και αποτελεί έναν ερευνητικό κλάδο με εφαρμογές σε διάφορα πεδία. Εμπνευσμένη από την κλασική θεωρία, προέκυψε η Κβαντική Θεωρία Παιγνίων, η οποία έχει αυξήσει σημαντικά τις δυνατότητες εφαρμογής και τα αποτελέσματα της κλασικής θεωρίας Παιγνίων. Η Εξελικτική Θεωρία Παιγνίων, επίσης παρακλάδι της κλασικής, αποτελεί κομβικό σημείο για την έρευνα, καθώς προσφέρει εναλλακτικές μεθόδους μοντελοποίησης προβλημάτωντου μικρόκοσμου. Τα αυτόματα είναι απλές αλλά εκφραστικές μηχανές με σκοπό την μοντελοποίηση καταστάσεων που αφορούν όλους τους τομείς της θεωρίας παιγνίων, προσφέροντας έναν εναλλακτικό τρόπο οπτικοποίησης και πιο ξεκάθαρες στρατηγικές για την επίλυση προβλημάτων.Η δομή της εργασίας έχει ως εξής: ορισμένοι σημαντικοί όροι περιγράφονται στην εισαγωγή και κατά την ανασκόπηση. Στις επόμενες δύο ενότητες μελετάται το εύρος της κλασικής και κβαντικής εξελικτικής Θεωρίας Παιγνίων και τη σχέση αυτών των πεδίων με μη συμβατικές μεθόδους υπολογισμού. Συγκεκριμένα, παρουσιάζεται η υπάρχουσα έρευνα σχετικά με τα εξελικτικά παιχνίδια και τη θεωρία των αυτομάτων, καθώς και τα είδη και την ποικιλία των αυτομάτων που προτείνουν οι ερευνητές για κάθε παιχνίδι, προκειμένου να αναλυθεί και να κατανοηθεί καλύτερα η δομή καιτα αποτελέσματα των παιχνιδιών. Τέλος, με βάση την ανάλυση, αναφέρονται οι καινοτομίες και οι ελλείψεις στη βιβλιογραφία.
Aldus Huxley-Ralph Cudworth
Authors: Μάνος Γεώργιος
Published: November 2023

Η παρούσα διδακτορική διατριβή με τίτλο: «Aldous Huxley-Ralph Cudworth: ένας ετεροχρονισμένος διάλογος», αποτελεί μια συγκριτική μελέτη με στόχο την ανάδειξη των ομοιοτήτων, δύο πολύ ιδιαίτερων στοχαστών,του δημοφιλούς συγγραφέα –μυθιστοριογράφου και υπερμάχου της Perennial Philosophy, Aldous Huxley (1894-1963) και του, λιγότερο γνωστού, φιλοσόφου και θεολόγου με κυρίαρχη θέση στο ρεύμα των Πλατωνιστών του Cambridge, Ralph Cudworth (1617-1688). Η σύνδεση των δύο αποτελεί μια πρωτότυπη σύλληψη που είχε ως αφετηρία τη μεταπτυχιακή μου εργασία με θέμα την ανάλυση της κοινωνικής θεωρίας του Ralph Cudworth, καθώς μια πρώτη απόπειρα σύνδεσης των δύο στοχαστών έγινε στο επίμετρο της συγκεκριμένης εργασίας. Πρωταρχική μέριμνα της διατριβής αποτελεί η ανάδειξη της σύνδεσης του θεολογικού στοιχείου και η επιρροή του στη διαμόρφωση του κοινωνικού γίγνεσθαι που επικρατεί και στους δύο στοχαστές. Κατόπιν η επισήμανση αλλής μίας, ίσως πιο καίριας ομοιότητας, η προσπάθεια και των δύο να αποσαφηνίσουν και να επαναπροσδιορίσουν το ρόλο της θρησκείας –αλλά και τη θέση του μυστικισμού- αναλύοντας τα φιλοσοφικά ρεύματα και θεολογικά δόγματα που εμπλέκονται. Στη διάκριση αυτή, εκτός από το εύρος παραπομπών και επιχειρημάτων από τους δύο μελετητές, περιλαμβάνεται και η ξεχωριστή θρησκευτική τοποθέτηση του καθενός, η καθαρά χριστιανική -από την πλευρά του Cudworth- και η εναλλακτικά θρησκευτική -από την πλευρά του Huxley- που επικεντρώνεται στον πυρήνα τριών εκ των επικρατέστερων θρησκειών (Χριστιανισμός,Βουδισμός,Ινδουισμός) στο πλαίσιο της Perennial Philosophy (και εξελικτικά με το ρεύμα των Tradistionalists). Συμπερασματικά, θα παρουσιαστεί η βαθύτερη σύνδεση των δύο στοχαστών, με τον μεταγενέστερο Huxley, να αποτελεί χρονικά, συνεχιστή της υπεράσπισης του θρησκευτικού στοιχείου απέναντι σε μορφές, όπως η τεχνολογία, που απειλούν την εξαφάνισή του, καθιστώντας το ξεπερασμένο και ανούσιο.
Γενετικά μονοπάτια στην παθογένεση των αδενωμάτων παραθυρεοειδή αδένα
Authors: Χόρτη Αγγελική
Published: November 2023

Οι παραθυρεοειδείς αδένες είναι βασικά λειτουργικά όργανα που έχουν καθοριστικό ρόλο στη ρύθμιση της ομοιόστασης του ασβεστίου, μαγνησίου και φωσφόρου στον οργανισμό, παράγοντας την παραθορμόνη. Το αδένωμα παραθυρεοειδή αδένα αποτελεί τη συχνότερη αιτία πρωτοπαθή υπερπαραθυρεοειδισμού και προκαλεί υπερπαραγωγή παραθορμόνης και υπερέκκριση ασβεστίου. Σκοπός την παρούσας μελέτης είναι η μελέτη του πρωτεϊνικού προφίλ σε ιστολογικά δείγματα αδενώματος του παραθυρεοειδή αδένα των πρωτεϊνών CALM1, ANXA2, MED12, MAPK1και VDR και περαιτέρω η διερεύνηση γενετικών αλλαγών στα υπό μελέτη αυτά γονίδια για το ρόλο τους στο εν λόγω πρωτέωμα. Στη μελέτη έλαβαν μέρος 60 ασθενείς με αδένωμα παραθυρεοειδή αδένα προς χειρουργική αντιμετώπιση και 60 υγιή άτομα νοσηλευόμενα για άλλη πάθηση χωρίς ιστορικό κακοήθειας ή αυτοάνοσης νόσου. Διενεργήθηκε λήψη δείγματος περιφερικού αίματος των ασθενών και των υγιών ατόμων, από το οποίο απομονώθηκε ολικό γονιδιωματικό DNA, ακολούθησε PCR και ηλεκτροφόρηση σε πηκτή αγαρόζης και μελέτη με την τεχνική πολυμορφισμών μήκους θραυσμάτων περιορισμού (RFLP). Για την ανοσοϊστοχημική μελέτη, χρησιμοποιήθηκε υλικό από την ιστολογική εξέταση των χειρουργικών παρασκευασμάτων, το οποίο μετά την διαδικασία αντιγονικής ανάκτησης και επώασης, εξετάσθηκε στο μικροσκόπιο. Πενήντα ασθενείς και 50 υγιή άτομα συμπεριλήφθηκαν στην γονιδιακή μελέτη. Ο πολυμορφισμός TaqI του γονιδίου VDR αναγνωρίσθηκε ως προδιαθεσικός παράγοντας για την ανάπτυξη αδενώματος παραθυρεοειδή αδένα. Οι λοιποί πολυμορφισμοί FokI, ApaI and BsmI (VDR) καθώς και rs7170178 (ANXA2), rs 1057519912 (MED12), rs12885713(CALM1) και rs1057519911 (MAPK1) δεν βρέθηκε να έχουν θετική συσχέτιση με το αδένωμα παραθυρεοειδή αδένα. Από την ανοσοϊστοχημική μελέτη, οι πρωτεΐνες ΑΝΧΑ2, ΜΑΡΚ1, MED12 και VDR αναγνώρισθηκαν με ήπια έως έντονη έκφραση στο αδένωμα παραθυρεοειδή αδένα, ενώ η πρωτεΐνη CALM1 δεν κατέστη δυνατό να αξιολογηθεί λόγω τεχνικών δυσκολιών και αποτυχιών στη διαδικασία της χρώσης. Η μελέτη της γονιδιακής βάσης του σποραδικού αδενώματος παραθυρεοειδή αδένα αποτελεί πεδίο αιχμής στην έρευνα με σκοπό την αναγνώριση των γενετικών μονοπατιών που εμπλέκονται στην παθογένεση της νόσου. Οι πρωτεΐνες VDR, ANXA2, MED12 και MAPK1 μπορούν να χρησιμοποιηθούν ως βιοδείκτες στη διάγνωση της νόσου, στη διαφοροδιάγνωση από την υπερπλασία και το καρκίνωμα παραθυρεοειδή αδένα καθώς και να συσχετισθούν με την κλινική συμπτωματολογία της νόσου.
Supply Chain Transparency and Blockchain Design
Authors: Cui Yao , Gaur Vishal , Liu Jingchen
Published: November 2023

Companies that are investing in blockchain technology to enhance supply chain transparency face challenges in fostering collaborations with others and deciding what information to share. Transparency over the actions of supply chain partners can improve operational decisions, but sharing own data on the blockchain can put firms at a competitive disadvantage. In this paper, we investigate the resulting questions of when blockchain should be adopted in a supply chain and how it should be designed by analyzing two ways that it can enhance supply chain transparency: making the manufacturer’s sourcing cost transparent to the buyers (i.e., vertical cost transparency) and making the ordering status of buyers transparent to each other (i.e., horizontal order transparency). Given such transparency, firms can design a smart contract that automates transactions contingent on the revealed information and enables them to realize better equilibrium outcomes. We find that blockchain increases supply chain profit only when the manufacturer’s capacity is large and decreases supply chain profit otherwise. If the capacity is sufficiently large to eliminate the buyers’ competition, blockchain leads to a win–win–win and the incentives of all participants are naturally aligned. If the capacity is only moderately large, the manufacturer needs to compensate the buyers to facilitate a blockchain implementation. However, if the capacity is small, horizontal order transparency enabled by the blockchain mitigates the buyers’ overorder incentive to compete for the manufacturer’s capacity and increases double marginalization. For such cases, we show that a blockchain that only enables vertical cost transparency should (and can) still be adopted in a range of small capacity cases, and we propose an access control layer for the logistics data to implement such a blockchain.

This paper was accepted by David Simchi-Levi, operations management.

Funding: J. Liu was supported by the National Natural Science Foundation of China [Grant 72101110] and The MOE (Ministry of Education in China) Project of Humanities and Social Sciences [Grant 20YJC630084].

Supplemental Material: The online appendix is available at https://doi.org/10.1287/mnsc.2023.4851 .
The state of health care and adult social care in England: focus on mental health
Authors: Williams Vicki
Published: November 2023

In this editorial, Vicki Williams discusses the report published by the Care Quality Commission on the state of health care and adult social care in England.
WIN THE COMPETITION BY LISTENING TO CUSTOMER VOICES: AN ANALYSIS OF RIDESHARING BUSINESS IN SURAKARTA
Authors: Astuti Septin Puji , Setiawan Brillian Aziz
Published: November 2023

Ridesharing has attracted worldwide attention due to its contribution to the environment, notably in reducing the number of privately owned vehicles, alleviating traffic congestion, and mitigating air pollution arising from private transportation. Currently, Indonesia’s ridesharing platform is a prominent player within the realm of popular e-commerce businesses. The use of technology has increased public interest in adopting ridesharing services. The goal of this study is to assess the competitive landscape among ridesharing companies operating in Surakarta, Indonesia. The participants are customers with experience with three ridesharing platforms: Grab, Go-Jek, and Maxim. This study implemented the Analytic Hierarchy Process to evaluate the competitiveness of ridesharing platforms. The benchmarks for platform selection include service quality, price, and promotional activities. Within the service quality domain, Parasuraman proposed five dimensions to serve as sub-criteria. The price criteria include three sub-criteria: low price, discounts, and affordability. Meanwhile, the promotional criteria encompass advertisement, vouchers, and digital influence as the sub-criteria. This study’s findings reveal a preference hierarchy among ridesharing alternatives from the customer’s perspective as follows: Grab (0.402), Go-Jek (0.365), and Maxim (0.226). Grab ranks highest in eight sub-criteria, whereas Go-Jek ranks highest in three sub-criteria. Conversely, Maxim consistently occupies the lowest rank. Notably, service quality emerges as the foremost priority, closely followed by price and promotion. Within the service quality criteria, assurance takes precedence, affordability leads the price criteria, and vouchers have the highest priority among promotional criteria.
Podcasting: The New Term Paper
Authors: Abnee Nina
Published: November 2023

Abstract: Today's generation of students are not like previous generations: they are creators, they are mobile, they communicate in short videos and 145 characters. And they listen to podcasts, get hacks from TikTok, and do not watch the evening news. This article discusses the creation of a DePaul University class in the College of Communication Public Relations and Advertising program (PRAD) in which students delve into contemporary issues in public relations and advertising while creating podcast episodes, a modern communications medium that is a big part of their daily lives.
Conference on Historical Analysis and Research in Marketing: Curiosities of the Atomic Age: A Spanish Informational Campaign about Modernity in the World
Authors: Aramendia-Muneta Maria Elena
Published: November 2023

Abstract: This Conference Spotlight presents the 2023 meeting, Esse quam videri: Marketing history for real . It was the 21st Biennial Conference on Historical Analysis and Research in Marketing (CHARM) which was hosted by the Hartman Center for Sales, Advertising & Marketing History at Duke University, Durham, NC. At this meeting, marketing and business historians, students, and academics gathered together to share research. Twenty-four short papers were introduced in twenty minute presentations on topics such as advertising history, the history of consumption, food and health marketing, historical method, marketing history in the arts, race in the marketplace, and marketing in the atomic and digital ages. The following recording titled "Curiosities of the Atomic Age: Information Campaign to Remark Modernity in the World" was presented by Maria Elena Aramendia-Muneta of the Universidad Pública de Navarra, Spain. It describes items from Spanish newspapers that introduced new products and technology from Europe and the US made possible by the invention of nuclear fission or atomic power. An awards banquet dinner announced the winners of the Stanley C. Hollander Best Paper and the David D. Monieson Best Student Paper, and attendees were able to tour the Hartman Center.
Reprint Retrospective: The Funhouse Mirror from Empowered: Popular Feminism and Popular Misogyny
Authors: Banet-Weiser Sarah
Published: November 2023

Abstract: This article is the first chapter from the 2018 book Empowered: Popular Feminism and Misogyny (Duke University Press). It critiques corporate feminist ads for focusing predominantly on individual empowerment and sentimentality, overlooking systemic barriers and broader inequalities. The chapter suggests these ads fit into shallow corporate social responsibility campaigns driven by consumerism. It also examines popular misogyny, detailing how men's rights groups parody feminist campaigns, often portraying women as threats to male power. Banet-Weiser urges readers to scrutinize the efficacy and intentions of feminist messaging in advertising, emphasizing the need to address existing power structures that disadvantage women in various spheres, including media and politics.
Conviction, Creativity, and Human Behavior in Advertising: An Interview with Saul Betmead
Authors: Betmead Saul , Timke Edward
Published: November 2023

Abstract: Drawing from his expansive career—from being chief strategy officer for VMLY&R to chief marketing officer at the UN World Food Programme to a preceptor, adviser, and mentor at the University of Oxford's Saïd Business School—Saul Betmead, a leading global marketer and strategist, offers a deep dive into the intricacies of the advertising industry. The interview covers the benefits of advertising; its influence on culture; the importance of diversity, equity, inclusion, and belonging (DEIB); and the crucial role of good mental health in creativity. He critiques the industry's shortsightedness, advocates for authentic brand purpose, and stresses the significance of long-term thinking. His advice for students, professors, and practitioners revolves around broadening perspectives, challenging assumptions, and foregrounding empathy. Betmead urges everyone to continually interrogate and redefine their assumptions, both personally and professionally.
Exhibiting the Complexities of Black Advertising History: A Review of "Let's March Forward Together"
Authors: Harrison Anthony Kwame
Published: November 2023

Abstract: This article reviews the Let's March Forward Together exhibition held at Duke University's Hartman Center for Sales, Advertising & Marketing History between February and July 2023. The installation highlights Black advertising professionals who contributed to shaping representations of Blackness in US American advertising. This review addresses how the exhibit showcases the complexities of responsible marketing, efforts to diversify the industry, and the tension between specialist and generalist approaches to advertising. Through the lens of Black consumer boycotts and historical advertising campaigns, the article underscores the intricate intersections of race, representation, and activism in advertising history, revealing the dynamic nature of Black identity and aspiration within a consumer-driven society.
The Advertising On-Ramp … and Destinations and Off-Ramps: An Interview with Belle Frank
Authors: Tag Nancy R. , Frank Belle
Published: November 2023

Abstract: This article captures a conversation between Belle Frank, the Chief Strategy Officer of VLMY&R Group Health Practice, and Nancy R. Tag, former creative director and professor and director of the Branding and Integrated Communication (BIC) Program at the City College of New York. The discussion covers the multifaceted landscape of the advertising industry, drawing from Frank's rich career and the insights encapsulated in her 2013 book The Advertising On-Ramp: Getting Your First Advertising Job . The conversation traverses the nuances of crafting strategic resumes that narrate a compelling story, honing interview skills, and the underestimated value of diverse backgrounds and transferable skills in advertising. Frank underscores the symbiotic relationship between advertising and culture, emphasizing the essential role of diverse perspectives in fostering creativity and innovation in the sector. She also envisages necessary updates to her book, highlighting many digital shifts impacting job searches. Frank and Tag envision an industry propelled by discerning professionals, balancing business imperatives with moral integrity. They accentuate the cruciality of adaptability, persistence, and choosing the right team in building a fulfilling career while fostering a culture of diversity and sustainable practices for a future generation of advertisers.
Seeing Horror through the Lens of Health: Embodying Dissociative Identity Disorder in The Babadook
Authors: Mitchell Paul
Published: November 2023

Abstract: This essay analyzes the representation of dissociative identity disorder in Jennifer Kent's debut feature, The Babadook (2014). Although the film's exploration of psychological themes such as maternal ambivalence, grief, and repression have already been widely discussed in the critical literature, I argue that such readings tend to mitigate the embodied nature of the suffering that Kent's film depicts. Using Arthur Frank's concept of chaos stories as well as Edward Branigan's work on film narrative, I show how The Babadook provides a valuable, fictional example of how dissociative identity disorder can be depicted in cinematic language. Through Kent's use of internal and external focalization, amongst other filmic techniques, the film promotes an ethic of witnessing whereby spectators can actively see the disorienting impact the protagonist's suffering has on her life. In this way, The Babadook gives health care practitioners insight into the complexity of her subjectivized illness experience.
A study on the spatial-temporal patterns and influencing factors of atmospheric vulnerability in the Pearl River Delta
Authors: Tang Bo , Tan Zhixiong
Published: November 2023

Atmospheric environmental assessment has emerged as a prominent area of research due to global climate change and regional atmospheric pollution issues. Accurate evaluation of atmospheric environmental vulnerability characteristics and understanding driving mechanisms are crucial for effective air pollution monitoring and prevention. This study focuses on the Pearl River Delta (PRD) region and employs the Vulnerability-Scoping-Diagram (VSD) model framework to establish an index system for assessing atmospheric environmental vulnerability based on exposure, sensitivity, and adaptability, combining the entropy value method and adopts Geographic Information System (GIS) for the time change and spatial evolution analysis, and finally utilizing the factor detection and interaction in Geodetector to explore the contribution degree of each driving factor of atmospheric environmental vulnerability and the exchange of influencing factors. The findings of this research are as follows: Firstly, the sensitivity index and resilience index of the atmospheric environment of the PRD exhibit an overall upward trend with fluctuations, while the exposure index demonstrates a pattern of initial increase, followed by a decrease, and subsequent increase with significant interannual variability. Secondly, the atmospheric environment vulnerability level of the PRD is primarily categorized as low and mild, with a negligible proportion of moderate vulnerability and no instances of severe or extreme vulnerability. The vulnerability index shows an initial increase followed by a subsequent decline from 2016 to 2020, indicating an overall improvement in the region’s atmospheric environment. Thirdly, notable variations exist in the atmospheric environment vulnerability indices among the nine cities in the PRD, in which moderate vulnerability and low vulnerability are mainly concentrated in Guangzhou, Shenzhen, Foshan, and Dongguan in the central part of the PRD. lower vulnerability is primarily observed in the eastern and western regions of the PRD characterized by favorable natural environments and limited human interference, such as Huizhou, Zhaoqing, and Zhuhai. Finally, the atmospheric environment vulnerability of the PRD is the result of the combined effect of various driving factors, among which the urban built-up area, PM2.5 concentration, SO2 concentration, population density and the share of tertiary industry in GDP are the key drivers.
‘Intraoperative predictors for clinical outcomes after microinvasive glaucoma surgery”
Authors: Rao Aparna , Mukherjee Sujoy
Published: November 2023

Purpose

To evaluate the clinical applicability of intraoperative predictors for surgical outcomes after gonioscopy-assisted transluminal trabeculotomy (GATT) and microincisional trabeculectomy (MIT).

Methods

Consecutive patients with primary, or secondary glaucoma (trauma, aphakic, or status post-retinal surgeries) with uncontrolled IOP>21mm Hg, who were scheduled to undergo GATT or MIT with or without significant cataract surgery, at a tertiary eye centre in East India between September 2021 to March 2023, were included. All surgeries were done by a single surgeon. Blanching and Trypan blue (0.4%) staining after intracameral injection using a 25 canula, were analysed in each video. The extent/pattern of blanching and blue staining in each eye was analysed objectively using an overlay of a circle with 12 sectors and a protractor tool to quantify the degrees or quadrants of blanching/staining. Multivariate regression was used to identify predictors for surgical success or the need for medications after surgery.

Result

Of 167 eyes that were included (male: female- 134: 33), 49 eyes and 118 eyes underwent GATT and MIT, respectively, with 81 of 167 eyes undergoing concurrent cataract surgery. All eyes had a significant reduction in the number of medications after surgery. Blanching was seen in 154 of 167 eyes in a mean of 2±1.8 quadrants with 41% of eyes showing a blanching effect in >3 quadrants. Of 99 of 167 eyes where Trypan blue staining was assessed, staining in a venular, diffuse haze, or reticular pattern of staining was seen in 73 eyes, 26 eyes showed blue staining in >2 quadrants, with 16% staining in >3 quadrants. Surgical success was not predicted by the quadrants of blanching, blue staining, or other clinical variables (age, visual field, baseline intraocular pressure, type of surgery). The variables significantly predicting the need for medications included blanch (r = -0.1, p = 0.03), and blue staining (r = -0.1, p = 0.04) in <2 quadrants.

Conclusions

Blanching and Trypan blue staining in >2 quadrants after GATT or MIT can serve as surrogate predictors for the need for medications. However more studies are mandated to find predictors for surgical success after GATT or MIT.
A simplified similarity-based approach for drug-drug interaction prediction
Authors: Shtar Guy , Solomon Adir , Mazuz Eyal , Rokach Lior , Shapira Bracha
Published: November 2023

Drug-drug interactions (DDIs) are a critical component of drug safety surveillance. Laboratory studies aimed at detecting DDIs are typically difficult, expensive, and time-consuming; therefore, developing in-silico methods is critical. Machine learning-based approaches for DDI prediction have been developed; however, in many cases, their ability to achieve high accuracy relies on data only available towards the end of the molecule lifecycle. Here, we propose a simple yet effective similarity-based method for preclinical DDI prediction where only the chemical structure is available. We test the model on new, unseen drugs. To focus on the preclinical problem setting, we conducted a retrospective analysis and tested the models on drugs that were added to a later version of the DrugBank database. We extend an existing method, adjacency matrix factorization with propagation (AMFP), to support unseen molecules by applying a new lookup mechanism to the drugs’ chemical structure, lookup adjacency matrix factorization with propagation (LAMFP). We show that using an ensemble of different similarity measures improves the results. We also demonstrate that Chemprop, a message-passing neural network, can be used for DDI prediction. In computational experiments, LAMFP results in high accuracy, with an area under the receiver operating characteristic curve of 0.82 for interactions involving a new drug and an existing drug and for interactions involving only existing drugs. Moreover, LAMFP outperforms state-of-the-art, complex graph neural network DDI prediction methods.
Nature and type of patient-reported safety incidents at a tertiary hospital in South Africa during the COVID-19 period (2018–2021)- A retrospective review
Authors: Singh Swabhavika , Mahomed Ozayr
Published: November 2023

The healthcare sector in South Africa has seen a rise in medical errors and negligence adversely affecting healthcare delivery. This study aimed to determine the nature and magnitude of Patient Safety Incidents at a tertiary hospital between April 2018 to March 2021 (the COVID-19 era). A retrospective review of Patient Safety Incidents forms and clinical records of inpatients above 12 years with a reported incident were included. The overall incidence of patient safety incidents was 4.40 PSIs per 10 000 patient-days. The majority of PSIs were harmful incidents (An incident that results in harm to a patient that is related to medical management, in contrast to disease complications or underlying disease) at 72.50% [145/200], followed by no harm incidents at 18.00% [36/200] and 9.50% [19/200] near-miss incidents. The five highest incident types were clinical process/procedure [83/200; 41.50%], behaviour [49/200; 24.50%], falls [28/200; 14%], complications [20/200; 10%], and pressure sores [11/200; 5.50%]. Incidents occurred more frequently within the week (83.50%) and during day shift (67.50%). Overall, the study showed low PSI reporting rates which is an inherent challenge with voluntary reporting. Notably, there has been an increasing trend in reporting. The results reflect a reporting culture more inclined to bring awareness to incidents that have negative outcomes.
Influence of polymorphisms in candidate genes on carcass and meat quality traits in rabbits
Authors: Safaa Hosam M. , Ragab Mohamed , Ahmed Marwa , El-Gammal Belal , Helal Mostafa
Published: November 2023

Candidate gene is a powerful approach to study gene-trait association and offers valuable information for genetic improvement using marker-assisted selection. The current work aimed to study the polymorphisms of four single nucleotide polymorphism (SNPs) at located growth hormone (GH), insulin-like growth factor-II (IGF-II), fat mass and obesity-associated (FTO), and insulin receptor substrate-1 (IRS-1) genes, and their association with the carcass, and meat quality traits in rabbits. The SNPs were genotyped using RFLP-PCR in New Zealand White and local Baladi rabbits. The results revealed that the heterozygous genotype was the most frequent in all cases, except for the FTO SNP in LB rabbits. There was a significant effect for GH genotypes on meat lightness after slaughter and hind-part weight. While, IGF-II mutation significantly affected slaughter, hot carcass, commercial carcass, and hind-part weights. The FTO SNP was associated with cooking loss and intramuscular fat weight, and the IRS-1 SNP was significantly associated with drip loss and intramuscular fat. Specific-breed effects were obtained for IGF-II SNP on cooking loss, and for the intramuscular fat. Although the results suggested that these mutations are useful candidate genes for selection, more research for detecting more variants associated with carcass and meat quality traits in rabbits are recommended.
Ranked severe maternal morbidity index for population-level surveillance at delivery hospitalization based on hospital discharge data
Authors: Kuklina Elena V. , Ewing Alexander C. , Satten Glen A. , Callaghan William M. , Goodman David A. , Ferre Cynthia D. , Ko Jean Y. , Womack Lindsay S. , Galang Romeo R. , Kroelinger Charlan D.
Published: November 2023

Background

Severe maternal morbidity (SMM) is broadly defined as an unexpected and potentially life-threatening event associated with labor and delivery. The Centers for Disease Control and Prevention (CDC) produced 21 different indicators based on International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) hospital diagnostic and procedure codes to identify cases of SMM.

Objectives

To examine existing SMM indicators and determine which indicators identified the most in-hospital mortality at delivery hospitalization.

Methods

Data from the 1993–2015 and 2017–2019 Healthcare Cost and Utilization Project’s National Inpatient Sample were used to report SMM indicator-specific prevalences, in-hospital mortality rates, and population attributable fractions (PAF) of mortality. We hierarchically ranked indicators by their overall PAF of in-hospital mortality. Predictive modeling determined if SMM prevalence remained comparable after transition to ICD-10-CM coding.

Results

The study population consisted of 18,198,934 hospitalizations representing 87,864,173 US delivery hospitalizations. The 15 top ranked indicators identified 80% of in-hospital mortality; the proportion identified by the remaining indicators was negligible (2%). The top 15 indicators were: restoration of cardiac rhythm; cardiac arrest; mechanical ventilation; tracheostomy; amniotic fluid embolism; aneurysm; acute respiratory distress syndrome; acute myocardial infarction; shock; thromboembolism, pulmonary embolism; cerebrovascular disorders; sepsis; both DIC and blood transfusion; acute renal failure; and hysterectomy. The overall prevalence of the top 15 ranked SMM indicators (~22,000 SMM cases per year) was comparable after transition to ICD-10-CM coding.

Conclusions

We determined the 15 indicators that identified the most in-hospital mortality at delivery hospitalization in the US. Continued testing of SMM indicators can improve measurement and surveillance of the most severe maternal complications at the population level.
Middle school students’ mental unwellness and academic performance in China: The effects of parental involvement
Authors: Liu Keqiao
Published: November 2023

This study investigated the relationship between the mental unwellness of middle school students in China and their academic performance in the subjects of Chinese, mathematics, and English. Additionally, this study explored the potential ameliorating effects of parental involvement variables (parental non-academic activity involvement and parent-child communication) on the adverse impact of mental unwellness on academic performance. The examination of the effects of parental involvement also considered the differential effects of involvement by mothers and fathers. This study utilized national longitudinal representative data from the China Education Panel Survey (CEPS). Findings of the two-level Hierarchical Linear Modeling (HLM) analyses indicated that mental unwellness in Grade 7 negatively impacted academic performance in the aforementioned subjects in Grade 8. Nonetheless, these adverse impacts were alleviated when the parental involvement variables were taken into account. Furthermore, the results revealed that mother-child communication and father-child communication had moderating effects on the negative relationship between mental unwellness and academic performance in Chinese and English, respectively. This study contributes to the existing literature by shedding light on the beneficial effects of parental involvement and highlighting the differential involvement of mothers and fathers.
Ernestina Godoy y Laura Ávalos (Eds.), Pensar la experiencia: ensayos desde la conciencia, el cuerpo y el arte
Authors: Samamé Luciana
Published: November 2023

En esta recensión, ofrezco un recorrido por los distintos ensayos que componen el libro "Pensar la experiencia: ensayos desde la conciencia, el cuerpo y el arte" en clave ética. Esta clave de lectura me permitirá afirmar en qué sentido la fenomenología es capaz de enriquecer la teoría ética normativa: 1) por un lado, enriqueciendo la noción de "experiencia moral"; 2) por el otro, complementando la perspectiva abstracta de aquélla a través de una fenomenología corporeizada.
experiencia del abandono del ser y el Ereignis
Authors: Gorosito Ulises
Published: November 2023

Consideramos que el Ereignis tiene como condición de posibilidad la experiencia del abandono del ser. Por ello, en el centro del viraje no habría ni un giro teológico ni solamente la reciprocidad entre el arrojamiento de lo Dasein por el ser y el proyecto del ser por lo Dasein. Experimentar el abandono del ser exige un salto al abismo, a la nada del ser, lo que abre el esenciar del ser desde su ausencia, tal como se muestra en la figura de la tierra. Este salto implica la transformación del hombre en Dasein: no habría una identidad entre ellos pues lo Dasein no es un ente. Por último, describiremos cómo no habría en esto último una negación de la acción ni de las consideraciones ónticas.
Lo demoníaco como fuerza de la naturaleza (Naturmagten) y su relación con el lenguaje en O lo uno o lo otro I de Kierkegaard
Authors: Rodríguez Yésica
Published: November 2023

En “Los estadios eróticos inmediatos, o el erotismo musical” de O lo uno o lo otro I (OO I) aparece una relación entre la música y los límites del lenguaje, donde ésta es presentada como el límite de la palabra precisamente porque hace referencia a lo demoníaco en el sentido de la fuerza de la naturaleza (Naturmagten). La fuerza de la naturaleza no puede expresarse por medio de la palabra ya que ésta es inmediata y el lenguaje implica una mediación. Por tanto, sostenemos que en OO I, hay un inicio de la problematización del lenguaje y sus límites, en cuyo contexto se entiende lo demoníaco como fuerza de la naturaleza. En este sentido,  en OO I, para el pseudónimo A,  lo demoníaco representa lo que no puede manifestarse por medio del lenguaje, pero sí por medio de la música.
Marc Bloch Dnes
Authors: Matějka Ondřej
Published: November 2023

Životu a dílu Marca Blocha, který byl v červnu 1944 popraven nacisty, se od 90. let 20. století věnuje zvýšená pozornost. Ve Francii po něm bylo pojmenováno několik škol a v Evropě i ve Spojených státech se stal sám předmětem historiografického studia.

Tento rostoucí zájem lze vysvětlit několika způsoby. Mediální pozornost věnovaná provokativním interpretacím jeho konfliktu s Lucienem Febvrem ohledně vydávání revue Annales v Německem okupované Paříži odráží vichistický syndrom francouzské kolektivní paměti. Blochovo zapojení do odboje bez stranické příslušnosti představuje pevný bod v období, kdy je role francouzského odboje za druhé světové války bolestně demytologizována. Navíc v době, kdy se dnešní Francie potýká s náboženským konfliktem, aktuálně rezonuje i jeho důsledné přihlášení se k republikánské asimilační tradici.

K Blochovu historiografickému odkazu se hlásí jak stoupenci pragmatické historiografie blízké Annales (G. Noiriel), kteří se odvolávají především na jeho válečný textový fragment - Apologie de l´histoire, tak představitelé školy, která je v jistém smyslu jeho konkurentem, tj. historie současnosti ztotožňované především s Henrym Roussoem, jež zdůrazňuje Blochovo svědectví o francouzské porážce v roce 1940 - L´étrange défaite. Zajímavé jsou také pokusy historiků o interpretaci Blochova rozhodnutí zapojit se do odboje navzdory pokročilému věku.
O dějinách a paměti
Authors: Třeštík Dušan
Published: November 2023

Na pozadí současných debat v České republice o "čistotě dějin" a potřebě chránit jakousi pomyslnou "správnou historii", praktikovanou odborníky, před zásahy a dezinterpretacemi novinářů, politiků a veřejnosti vůbec, autor upozorňuje na pokrok, který přináší současný výzkum historické "paměti" národů a dalších skupin. I když "paměť" samozřejmě není "správná", je autentická a legitimní. Není nepřítelem historie vytvářené odborníky, ale jejím partnerem v dialogu. Historici musí vést dialog s veřejností na co nejširší bázi, musí se jí otevřít a neskrývat se před ní za štít svého pozitivistického scientismu, který je sám plný nebezpečných prasklin.
Tomáš Hermann, Emanuel Rádl a české dějepisectví. Kritika českého dějepisectví ve sporu o smysl českých dějin
Authors: Horský Jan
Published: November 2023

Recenze
Zdeněk Vašíček, Podmínky volby
Authors: Hermann Tomáš
Published: November 2023

Recenze
Robert Sak, Rieger. Konservativec nebo liberál? Martina Winkler, Karel Kramář (1860–1937)
Authors: Havelka Miloš
Published: November 2023

Recenze
Joachim Eibach, Günther Lottes (Hg.), Kompass der Geschichtswissenschaft. Ein Handbuch
Authors: Horský Jan
Published: November 2023

Recenze