bluuebunny/crossref_metadata_2025 huggingface dataset:
Process Optimization and Robustness Analysis of Ammonia–Coal Co-Firing in a Pilot-Scale Fluidized Bed Reactor
Authors: Cardoso João Sousa , Silva Valter , Chavando Jose Antonio , Eusébio Daniela , Hall Matthew J.
Published: April 2024

A computational fluid dynamics (CFD) model was coupled with an advanced statistical strategy combining the response surface method (RSM) and the propagation of error (PoE) approach to optimize and test the robustness of the co-firing of ammonia (NH3) and coal in a fluidized bed reactor for coal phase-out processes. The CFD model was validated under experimental results collected from a pilot fluidized bed reactor. A 3k full factorial design of nine computer simulations was performed using air staging and NH3 co-firing ratio as input factors. The selected responses were NO, NH3 and CO2 emissions generation. The findings were that the design of experiments (DoE) method allowed for determining the best operating conditions to achieve optimal operation. The optimization process identified the best-operating conditions to reach stable operation while minimizing harmful emissions. Through the implementation of desirability function and robustness, the optimal operating conditions that set the optimized responses for single optimization showed not to always imply the most stable set of values to operate the system. Robust operating conditions showed that maximum performance was attained at high air staging levels (around 40%) and through a balanced NH3 co-firing ratio (around 30%). The results of the combined multi-optimization process performance should provide engineers, researchers and professionals the ability to make smarter decisions in both pilot and industrial environments for emissions reduction for decarbonization in energy production processes.
The Efficiency of the Kalman Filter in Nodal Redundancy
Authors: Moyano Henrry , Vargas Luis
Published: April 2024

The growing integration of distributed energy resources underscores the critical importance of having precise insights into the dynamics of an electrical power system (EPS). Consequently, an estimator must align with the EPS dynamics to enhance the overall reliability, safety, and system stability. This alignment ensures that operators can make informed decisions during system operations. An initial step in gaining insight into the system’s state involves examining its state vector, which is represented by voltage phasors. These results are derived through the application of a distributed state-estimation process in large-scale systems. This study delved into the effectiveness of Bayesian filters, with a particular emphasis on the extended Kalman filter (EKF) algorithm in the context of distributed state estimation. To analyze the outcomes, the nodal partitioning process was incorporated within the distributed state-estimation framework. The synergy between the EKF algorithm and the partitioning method was evaluated using the IEEE118 test system.
Correction: Badea et al. The Energy Storage Technology Revolution to Achieve Climate Neutrality. Energies 2024, 17, 140
Authors: Badea Ioana-Cristina , Șerban Beatrice-Adriana , Anasiei Ioana , Mitrică Dumitru , Olaru Mihai Tudor , Rabin Andrey , Ciurdaș Mariana
Published: April 2024

In the original publication [...]
The Use of Renewable Energy Sources in Road Construction and Public Transport: A Review
Authors: Kurz Dariusz , Bugała Artur , Głuchy Damian , Kasprzyk Leszek , Szymenderski Jan , Tomczewski Andrzej , Trzmiel Grzegorz
Published: April 2024

The development and advantages of renewable energy technologies mean that their areas of application are constantly expanding. The development of roads, transport systems, and electromobility also increases the demand for electricity. Roads occupy a certain area that could be used to install wind turbines or photovoltaic systems that could be used to power, among others, electric vehicle charging stations and road technical infrastructure facilities (travel service areas, tunnel lighting, road signs). There are many examples around the world where such solutions have been used. This critical review of existing solutions and the possibilities of their application in new places may contribute to further development and research in this area. Particular attention was paid to the possibility of using renewable energy systems in Poland, which can be successfully transferred to other countries with a similar climate.
Assessing the Theoretical, Minimal Intervention Potential of Floating Solar in Greece: A Policy-Oriented Planning Exercise on Lentic Water Systems of the Greek Mainland
Authors: Athanasiou Despoina , Zafirakis Dimitrios
Published: April 2024

According to the recent revision of the Greek National Energy and Climate Plan, the country sets out to accomplish an ambitious target concerning the integration of renewables in the local electricity mix during the ongoing decade, at the levels of 80% by 2030. This implies the need to more than double the existing wind and PV capacity at the national level, which in turn introduces numerous challenges. Amongst them, spatial planning for new RES installations seems to be the most demanding, with the adoption of novel technological solutions in the field of RES potentially holding a key role. New technologies, like offshore wind and floating solar, are gradually gaining maturity and may offer such an alternative, challenged at the same time however by the need to entail minimum disruption for local ecosystems. To that end, we currently assess the theoretical potential of floating PVs for lentic water systems of the Greek mainland. We do so by looking into 53 different lentic water systems across the Greek territory that meet the constraint of 1 km2 minimum surface area, and we proceed with the estimation of the relevant floating PV capacity per system under the application of a minimal intervention approach, assuming PV coverage of 1% over the total lentic water system area. In this context, our findings indicate a maximum, aggregate theoretical capacity that could exceed 2 GWp at the national level, with the respective annual energy yield reaching approximately 4 TWh or, equivalently, >6% of the country’s anticipated annual electricity consumption in 2030. Finally, our results extend further, offering a regional level analysis and a set of policy directions and considerations on the development of floating solar in Greece, while also designating the energy merits of floating PVs against similar, land-based installations.
Optimizing Curdlan Synthesis: Engineering Agrobacterium tumefaciens ATCC31749 for Enhanced Production Using Dextrin as a Carbon Source
Authors: Yu Tingting , Wang Yu , Wang Wei , Zhang Yonggang , Zhang Yanmin , Han Hongyu , Liu Yang , Zhou Siduo , Dong Xueqian
Published: April 2024

A key goal in current research on industrial curdlan production is the expansion of carbon sources for fermentation. In this study, a recombinant bacterial strain, sp-AmyAXCC, capable of fermenting and synthesizing curdlan using dextrin as a carbon source, was produced via heterologous expression of IPTG-inducible α-amylase from Xanthomonas campestris NRRL B-1459 in Agrobacterium tumefaciens ATCC31749. External expression of the enzyme was confirmed by western blotting, and the expression levels of exogenous proteins during the fermentation process were monitored. Additionally, the properties of the curdlan product were characterized using attenuated total reflectance-Fourier transform infrared spectroscopy and X-ray diffraction. The recombinant strain produced curdlan at a titer of 30.40 ± 0.14 g/L, gel strength of 703.5 ± 34.2 g/cm2, and a molecular weight of 3.58 × 106 Da, which is 33% greater than the molecular weight of native curdlan (2.69 × 106 Da). In the batch fermentation of sp-AmyAXCC with 12% dextrin as a carbon source, the titer of curdlan was 66.7 g/L with a yield of 0.56 g/g, and a productivity rate of 0.62 g/L/h at 108 h. The results of this study expand the substrate spectrum for Agrobacterium fermentation in curdlan production and provides guidance for further industrialization of curdlan production.
Novel Approach towards a Fully Deep Learning-Based IoT Receiver Architecture: From Estimation to Decoding
Authors: Boeding Matthew , Hempel Michael , Sharif Hamid
Published: April 2024

As the Internet of Things (IoT) continues to expand, wireless communication is increasingly widespread across diverse industries and remote devices. This includes domains such as Operational Technology in the Smart Grid. Notably, there is a surge in resource-constrained devices leveraging wireless communication, especially with the advances of 5G/6G technology. Nevertheless, the transmission of wireless communications demands substantial power and computational resources, presenting a significant challenge to these devices and their operations. In this work, we propose the use of deep learning to improve the Bit Error Rate (BER) performance of Orthogonal Frequency Division Multiplexing (OFDM) wireless receivers. By improving the BER performance of these receivers, devices can transmit with less power, thereby improving IoT devices’ battery life. The architecture presented in this paper utilizes a depthwise Convolutional Neural Network (CNN) for channel estimation and demodulation, whereas a Graph Neural Network (GNN) is utilized for Low-Density Parity Check (LDPC) decoding, tested against a proposed (1998, 1512) LDPC code. Our results show higher performance than traditional receivers in both isolated tests for the CNN and GNN, and a combined end-to-end test with lower computational complexity than other proposed deep learning models. For BER improvement, our proposed approach showed a 1 dB improvement for eliminating BER in QPSK models. Additionally, it improved 16-QAM Rician BER by five decades, 16-QAM LOS model BER by four decades, 64-QAM Rician BER by 2.5 decades, and 64-QAM LOS model BER by three decades.
A Fair Crowd-Sourced Automotive Data Monetization Approach Using Substrate Hybrid Consensus Blockchain
Authors: Samuel Cyril Naves , Verdier François , Glock Severine , Guitton-Ouhamou Patricia
Published: April 2024

This work presents a private consortium blockchain-based automotive data monetization architecture implementation using the Substrate blockchain framework. Architecture is decentralized where crowd-sourced data from vehicles are collectively auctioned ensuring data privacy and security. Smart Contracts and OffChain worker interactions built along with the blockchain make it interoperable with external systems to send or receive data. The work is deployed in a Kubernetes cloud platform and evaluated on different parameters like throughput, hybrid consensus algorithms AuRa and BABE, along with GRANDPA performance in terms of forks and scalability for increasing node participants. The hybrid consensus algorithms are studied in depth to understand the difference and performance in the separation of block creation by AuRa and BABE followed by chain finalization through the GRANDPA protocol.
Study on a Strong Polymer Gel by the Addition of Micron Graphite Oxide Powder and Its Plugging of Fracture
Authors: Shi Bin , Zhang Guangming , Zhang Lei , Wang Chengjun , Li Zhonghui , Chen Fangping
Published: April 2024

It is difficult to plug the fracture water channeling of a fractured low-permeability reservoir during water flooding by using the conventional acrylamide polymer gel due to its weak mechanical properties. For this problem, micron graphite powder is added to enhance the comprehensive properties of the acrylamide polymer gel, which can improve the plugging effect of fracture water channeling. The chemical principle of this process is that the hydroxyl and carboxyl groups of the layered micron graphite powder can undergo physicochemical interactions with the amide groups of the polyacrylamide molecule chain. As a rigid structure, the graphite powder can support the flexible skeleton of the original polyacrylamide molecule chain. Through the synergy of the rigid and flexible structures, the viscoelasticity, thermal stability, tensile performance, and plugging ability of the new-type gel can be significantly enhanced. Compared with a single acrylamide gel, after adding 3000 mg/L of micrometer-sized graphite powder, the elastic modulus, the viscous modulus, the phase transition temperature, the breakthrough pressure gradient, the elongation at break, and the tensile stress of the acrylamide gel are all greatly improved. After adding the graphite powder to the polyacrylamide gel, the fracture water channeling can be effectively plugged. The characteristics of the networked water flow channel are obvious during the injected water break through the gel in the fracture. The breakthrough pressure of water flooding is high. The experimental results are an attempt to develop a new gel material for the water plugging of a fractured low-permeability reservoir.
Plant-Growth-Promoting Rhizobacteria and Arbuscular Mycorrhizal Fungi May Improve Soil Fertility and the Growth, Nutrient Uptake, and Physiological Performance of Batavia Lettuce (Lactuca sativa L. var. longifolia) Plants
Authors: Chatzistathis Theocharis , Zoukidis Konstantinos , Vasilikiotis Christos , Apostolidis Antonios , Giannakoula Anastasia E. , Bountla Areti , Chatziathanasiadis Apostolos
Published: April 2024

A greenhouse experiment was realized to investigate the effects of plant-growth-promoting rhizobacteria (PGPR) and arbuscular mycorrhizal fungi (AMF) on soil quality and the growth, nutrient uptake, and physiological performance of Batavia lettuce (Lactuca sativa L. var. longifolia). For this purpose, six fertilization treatments were applied: (i) inorganic fertilization (I.F.—control, i.e., usual/conventional fertilization), (ii) I.F. + PGPR, (iii) I.F. + PGPR + AMF, (iv) manure (MAN), (v) MAN + PGPR, and (vi) MAN + PGPR + AMF. Soil fertility was influenced by the treatments, and soil respiration (CO2 flux) was significantly increased after applications of PGPR and AMF. Following MAN fertilization in particular, an approximately sixfold higher soil respiration value was recorded following the MAN + PGPR + AMF treatment compared to the control (I.F.). Root, leaf, and total biomass dry weights were significantly affected by the PGPR and AMF applications, mainly following the I.F. treatment. In contrast, K, Mg, and Fe uptake was significantly influenced by PGPR and AMF application following the MAN treatment. The SPAD value, performance index (PI), photosynthetic rate, and stomatal conductance were significantly higher in the I.F. + PGPR + AMF-treated plants compared to the control plants. Overall, these data prove the beneficial roles of PGPR and AMF in soil quality and fertility and the nutrient uptake and physiological performance of lettuce plants. However, further clarification is needed in the near future to test the interaction effects between PGPR, AMF, and the type of fertilizer used (organic or inorganic).
Ultraviolet-C Light and Peracetic Acid Extend the Shelf Life of Fresh and Frozen Strawberries
Authors: Nicolau-Lapeña Iolanda , Ortiz Jordi , Viñas Inmaculada , Abadias Maribel , Bobo Gloria , Aguiló-Aguayo Ingrid
Published: April 2024

The postharvest life of strawberries is short, and disinfection processes for fresh-cut and frozen strawberries are needed to address the risk posed by foodborne pathogens in this kind of product. For this, a process involving immersion in a 40 mg L−1 peracetic acid (PA) solution accompanied by the use of an emerging technology, ultraviolet-C for 2 min, was studied for its impact on strawberry quality and microbial load as a novel alternative method to chlorine sanitation. The shelf life of the washed strawberries was evaluated in fresh (whole or fresh-cut) product for 11 days at 4 °C and in product that had been frozen for 12 months at –20 °C (air or modified atmosphere, 20% CO2, 5% O2, and 75% N2). After washing, total aerobic mesophylls, yeast, and mold decreased by 0.5–1.0 log units and these counts remained low during storage. The fresh and fresh-cut fruits’ firmness (2.3 ± 0.5 N at day 11) and lightness (expressed by L*, averaging 31.0 ± 0.1) were maintained. Although antioxidant activity, expressed by the amount of radical 2,2-diphenyl-1-picrylhydrazyl (DPPH), decreased during storage in fresh-cut samples, total ferric reducing antioxidant power (FRAP), total phenolic content, and total anthocyanin content were maintained in all the formats during storage (averaging 1.33 ± 0.04 g kg−1 ascorbic acid equivalents, 0.212 ± 0.01 g kg−1 gallic acid equivalents, and 0.03 ± 0.01 g kg−1 pelargonidine-3-glucoside). An increase in red color (from 32.1 to 39.3 a* values) and a loss of firmness of up to 46.8% was observed after the first month of frozen storage with no changes in the nutritional quality. Considering the sanitizing effect of water UV-C with peracetic acid (WUVPA) and the results obtained in the present study, the addition of this process in the production chain of strawberries could be an effective method to maintain the shelf life of the fruits, especially for fresh-cut strawberries.
Design of Multi-Functional Bio-Safe Dental Resin Composites with Mineralization and Anti-Biofilm Properties
Authors: Yun Jiaojiao , Burrow Michael F. , Matinlinna Jukka P. , Ding Hao , Chan Sin Man (Rosalind) , Tsoi James K. H. , Wang Yan
Published: April 2024

This study aims to develop multi-functional bio-safe dental resin composites with capabilities for mineralization, high in vitro biocompatibility, and anti-biofilm properties. To address this issue, experimental resin composites consisting of UDMA/TEGDMA-based dental resins and low quantities (1.9, 3.8, and 7.7 vol%) of 45S5 bioactive glass (BAG) particles were developed. To evaluate cellular responses of resin composites, MC3T3-E1 cells were (1) exposed to the original composites extracts, (2) cultured directly on the freshly cured resin composites, or (3) cultured on preconditioned composites that have been soaked in deionized water (DI water), a cell culture medium (MEM), or a simple HEPES-containing artificial remineralization promotion (SHARP) solution for 14 days. Cell adhesion, cell viability, and cell differentiation were, respectively, assessed. In addition, the anti-biofilm properties of BAG-loaded resin composites regarding bacterial viability, biofilm thickness, and biofilm morphology, were assessed for the first time. In vitro biological results demonstrated that cell metabolic activity and ALP expression were significantly diminished when subjected to composite extracts or direct contact with the resin composites containing BAG fillers. However, after the preconditioning treatments in MEM and SHARP solutions, the biomimetic calcium phosphate minerals on 7.7 vol% BAG-loaded composites revealed unimpaired or even better cellular processes, including cell adhesion, cell proliferation, and early cell differentiation. Furthermore, resin composites with 1.9, 3.8, and 7.7 vol% BAG could not only reduce cell viability in S. mutans biofilm on the composite surface but also reduce the biofilm thickness and bacterial aggregations. This phenomenon was more evident in BAG7.7 due to the high ionic osmotic pressure and alkaline microenvironment caused by BAG dissolution. This study concludes that multi-functional bio-safe resin composites with mineralization and anti-biofilm properties can be achieved by adding low quantities of BAG into the resin system, which offers promising abilities to mineralize as well as prevent caries without sacrificing biological activity.
Candida Non-albicans and Non-auris Causing Invasive Candidiasis in a Fourth-Level Hospital in Colombia: Epidemiology, Antifungal Susceptibility, and Genetic Diversity
Authors: Hernández-Pabón Juan Camilo , Tabares Bryan , Gil Óscar , Lugo-Sánchez Carlos , Santana Aldair , Barón Alfonso , Firacative Carolina
Published: April 2024

Increasingly common and associated with healthcare settings, Candida infections are very important, since some species of this genus can develop antifungal resistance. We contribute data on the epidemiology, antifungal susceptibility, and genetic diversity of Candida non-albicans and non-auris affecting critically ill patients in a fourth-level hospital in Colombia. Ninety-seven isolates causing invasive infections, identified by conventional methods over 18 months, were studied. Data from patients affected by these yeasts, including sex, age, comorbidities, treatment, and outcome, were analysed. The antifungal susceptibility of the isolates was determined, and the ribosomal DNA was sequenced. Candida parapsilosis, Candida tropicalis, Candida glabrata, Candida dubliniensis, and Candida guilliermondii caused 48.5% of all cases of invasive candidiasis. The species were mainly recovered from blood (50%). Patients were mostly men (53.4%), between 18 days and 93 years old, hospitalized in the ICU (70.7%). Overall mortality was 46.6%, but patients in the ICU, using antibiotics, with diabetes mellitus, or with C. glabrata infections were more likely to die. Resistant isolates were identified in C. parapsilosis, C. tropicalis, and C. glabrata. This study provides epidemiological data for the surveillance of emerging Candida species, highlighting their clinical impact, as well as the emergence of antifungal resistance and clonal dispersal.
Iron–Carbon Nanospheres as Promising Material for Magnetic Assisted Adsorption and Separation of Impurities from a Liquid Phase
Authors: Pełech Iwona , Lewinska Sabina , Arciszewska Monika , Khaliq Abdul , Ślawska-Waniewska Anna , Sibera Daniel , Staciwa Piotr , Narkiewicz Urszula
Published: April 2024

The composites containing various iron compounds and highly microporous carbon spheres were produced and investigated for structural and magnetic properties. Iron citrate, nitrate and chloride were used to prepare samples and the obtained products contained iron, iron carbide or magnetite. All the produced samples were characterized by high porosity and good magnetic properties. The coupling of the high porosity of carbon spheres with magnetic properties of iron compounds provides a potential application of the composites to removal of impurities from water, followed by a magnetic separation of the sorbent.
Investigation of Mechanical Properties of Polymer-Infiltrated Tetrapodal Zinc Oxide in Different Variants
Authors: Scherer Franziska , Wille Sebastian , Saure Lena , Schütt Fabian , Wellhäußer Benjamin , Adelung Rainer , Kern Matthias
Published: April 2024

The aim of this study was to evaluate the influence of weight ratio, the shape of the precursor particles, and the application of a phosphate-monomer-containing primer on the mechanical properties of polymer infiltrated ceramic networks (PICNs) using zinc oxide. Two different types of zinc oxide particles were used as precursors to produce zinc oxide networks by sintering, each with two different densities resulting in two different weight ratios of the PICNs. For each of these different networks, two subgroups were built: one involving the application of a phosphate-monomer-containing primer prior to the infiltration of Bis-GMA/TEGDMA and one without. Elastic modulus and flexural strength were determined by using the three-point bending test. Vertical substance loss determined by the chewing simulation was evaluated with a laser scanning microscope. There was a statistically significant influence of the type of precursor particles on the flexural strength and in some cases on the elastic modulus. The application of a primer lead to a significant increase in the flexural strength and in most cases also in the elastic modulus. A higher weight ratio of zinc oxide led to a significantly higher elastic modulus. Few statistically significant differences were found for the vertical substance loss. By varying the shape of the particles and the weight fraction of zinc oxide, the mechanical properties of the investigated PICN can be controlled. The use of a phosphate-monomer-containing primer strengthens the bond between the infiltrated polymer and the zinc oxide, thus increasing the strength of the composite.
An Experimental Method to Capture the Thermal Conductivity Coefficient of Fine-Grained Concretes during Transition from Liquid to Solid
Authors: Schwarz Yannik , Ratke Denis , Sanio David , Meurer Thomas , Mark Peter
Published: April 2024

During the transition from liquid to solid, the thermal conductivity coefficient λ of concrete decreases. Although λ of hardened concrete is well investigated, there is limited research on the transition from liquid to solid and how it depends on hydration. Currently, only simplified qualitative approaches exist for the liquid state and the transient process. An experimental method is not available. For this purpose, a test rig is designed to experimentally capture the evolution of λ for fine-grain concretes during transition. The performance of the test setup is evaluated on a characteristic high-performance concrete (HPC). The results are compared to theoretical predictions from the literature. The developed test rig is mapped in a digital twin to investigate extended boundary conditions, such as different heat sources and temperatures of the experimental setup. It allows the experiment to be repeated and optimized for different setups with little effort. The test principle is as follows: A liquid concrete sample is heated through a controlled external source, while the transient temperature distribution over the height is measured with a fiber optic sensor. The thermal conductivity is derived from the heat flux induced and the temperature distribution over an evaluation length. Experiments show that λ in the liquid state is approximately 1.4 times greater than in the solid state and exponentially decreases for the transient process. Numerical results on the digital twin indicate that the robustness of the results increases with the temperature of the heat source. Moreover, the derivation in λ turns out to be strongly dependent on the evaluation length. A length of three times the maximum grain diameter is recommended.
Tuning the Piezoelectric Performance of K0.5Na0.5NbO3 through Li Doping: Insights from Structural, Elastic and Electronic Analyses
Authors: Li Hui , Zhou Tianxiang , Xu Kang , Wang Han , Lu Wenke , Liu Jinyi
Published: April 2024

The structural, elastic, piezoelectric, and electronic properties of Li-doped K0.5Na0.5NbO3 (K0.5−xNa0.5−yLix+yNbO3, KNN-L) are calculated. The properties of KNN-L are related to the Li-doping content and the replaced K or Na atoms. The bulk modulus, the shear modulus, and Young’s modulus of KNN-L are mostly higher than those of KNN, and the hardness value increases. The Poisson ratio of KNN-L is lower than that of most KNN, and the ductility is reduced. All doped structures are direct band gap semiconductors. K0.5Na0.375Li0.125NbO3 has the largest piezoelectric charge constant, d33 = 44.72 pC/N, in the respective structures, which is 1.5 fold that of K0.5Na0.5NbO3 (29.15 pC/N). The excellent piezoelectric performance of Li-doping KNN-L was analyzed from the insights of elastic and electronic properties.
Towards Understanding Formation Mechanism of Cellular Structures in Laser Powder Bed Fused AlSi10Mg
Authors: Zhang Xiaoying , Zhang Xingpeng , Liu Wenbo , Jiang Aoke , Long Yu
Published: April 2024

A new approach is proposed that identifies three different zones of the Si-rich network structure (the cellular structure) in laser powder bed fused (LPBF) AlSi10Mg alloy, based on the variation in morphology, grain growth transition, and melt pool solidification conditions. The three identified zones are denoted in the present work as the liquid solidification zone (LSZ), the mushy solidification zone (MSZ), and the heat affected zone (HAZ). The LSZ is the result of liquid–solid transformation, showing small planar growth at the boundary and large cellular growth in the center, while the MSZ is related to a semisolid reaction, and the HAZ arises from a short-time aging process. The boundary between the LSZ and MSZ is identified by the change of grain growth direction and the Si-rich network advancing direction. The boundary between MSZ and HAZ is identified by the start of the breakdown of the Si-rich network. In addition, it is found that the fracture is generated in and propagates along the HAZ during tensile tests.
Fracture Resistance of 3D-Printed Occlusal Veneers Made from 3Y-TZP Zirconia
Authors: Zenthöfer Andreas , Fien Dennis , Rossipal Johannes , Ilani Ali , Schmitt Clemens , Hetzler Sebastian , Rammelsberg Peter , Rues Stefan
Published: April 2024

The aim of this paper was to evaluate the fracture resistance of 3D-printed zirconia occlusal veneers (OVs) of different thicknesses and supported by different abutment materials. Materials and Methods: The standard OV of a natural molar was prepared and digitized using a laboratory 3D scanner. The resulting digital tooth abutment was milled either using cobalt–chromium (CoCr) or a fiber-reinforced composite (FRC). All the abutments were digitized and standardized OVs (30° tilt of all the cusps) designed with 0.4 mm, 0.6 mm, or 0.8 mm wall thicknesses. The OVs were fabricated using either the Programill PM7 milling device (Ivoclar Vivadent, PM) or one of two 3D zirconia printers, Cerafab 7500 (Lithoz, LC) or Zipro-D (AON, ZD). The ZD samples were only tested on CoCr abutments. The completed OVs were luted to their abutments and subjected to artificial aging, consisting of thermocycling and chewing simulation before fracture testing with a steel sphere (d = 8 mm) as an antagonist with three contact points on the occlusal OV surface. Besides the total fracture resistance Fu,tot, the lowest contact force Fu,cont leading to the local fracture of a cusp was of interest. The possible effects of the factors fabrication approach, wall thickness, and abutment material were evaluated using ANOVA (α = 0.05; SPSS Ver.28). Results: The total fracture resistance/contact forces leading to failure ranged from Fu,tot = 416 ± 83 N/Fu,cont = 140 ± 22 N for the 0.4 mm OVs fabricated using LC placed on the FRC abutments to Fu,tot = 3309 ± 394 N (ZD)/Fu,cont = 1206 ± 184 N (PM) for the 0.8 mm thick OVs on the CoCr abutments. All the factors (the fabrication approach, abutment material, and OV wall thickness) had an independent effect on Fu,tot as well as Fu,cont (p < 0.032). In pairwise comparisons for Fu,tot of the OVs luted to the CoCr abutments, the ZD samples statistically outperformed the LC- and PM-fabricated teeth irrespective of the thickness (p < 0.001). Conclusions: Within the limitations of this study, the printed occlusal veneers exhibited comparable fracture resistances to those of the milled variants. However, more resilient abutments (FRC as a simulation of dentine) as well as a thinner wall thickness led to reduced OV fracture resistance, suggesting that 0.4 mm thick zirconia OVs should not be unreservedly used in every clinical situation.
High-Performance Nanoscale Metallic Multilayer Composites: Techniques, Mechanical Properties and Applications
Authors: Ebrahimi Mahmoud , Luo Bangcai , Wang Qudong , Attarilar Shokouh
Published: April 2024

Due to their exceptional properties and diverse applications, including to magnetic devices, thermoelectric materials, catalysis, biomedicine, and energy storage, nanoscale metallic multilayer composites (NMMCs) have recently attracted great attention. The alternating layers of two or more metals that make up NMMCs are each just a few nanometers thick. The difficulties in producing and synthesizing new materials can be overcome by using nanoscale multilayer architectures. By adjusting the layer thickness, composition, and interface structure, the mechanical properties of these materials can be controlled. In addition, NMMCs exhibit unusually high strength at thin layer thicknesses because the multilayers have exceptionally high strength, as the individual layer thicknesses are reduced to the nanoscale. The properties of NMMCs depend on the individual layers. This means that the properties can be tuned by varying the layer thickness, composition, and interface structure. Therefore, this review article aims to provide a comprehensive overview of the mechanical properties and the application of high-performance NMMCs. The paper briefly discusses the fabrication methods used to produce these composites and highlights their potential in various fields, such as electronics, energy storage, aerospace, and biomedical engineering. Furthermore, the electrical conductivity, mechanical properties, and thermal stability of the above composite materials are analyzed in detail. The review concludes with a discussion of the future prospects and challenges associated with the development of NMMCs.
XPS Investigation of Magnetization Reduction Behavior and Kinetics of Oolitic Hematite in Gas-Based Roasting
Authors: Li Mengfei , Zhang Hanquan , Yang Fan , Chen Tiejun , Lu Manman , Yu Hong
Published: April 2024

Magnetization reduction roasting is an important method for the utilization of oolitic magnetite. In this study, the magnetization reduction behavior and kinetics of oolitic hematite in gas-based roasting were systematically investigated by X-ray photoelectron spectroscopy (XPS). The results revealed that under optimal roasting conditions of 650 °C, a roasting time of 60 min, and a CO concentration of 30%, the magnetization reduction rate of the roasted product reached 44.34%. Furthermore, the weak magnetic separation concentrate presented a TFe of 58.09% and a concentrate iron recovery of 94.3%. The results of the XPS spectrum indicated that the peak area ratio (Fe2+/Fe3+) gradually increased with an increase in roasting temperature, roasting time, and CO concentration, while over-reduction occurred when the roasting temperature exceeded 750 °C. The investigation of magnetization roasting kinetics for varying particle sizes demonstrated that the magnetization reduction process is controlled by chemical reaction, with a corresponding activation energy range of 42.96 kJ/mol to 63.29 kJ/mol, indicating the particle size has little effect on the magnetization reduction of oolitic hematite.
Electrical Resistivity and Phase Evolution of Fe–N Binary System at High Pressure and High Temperature
Authors: Wang Yunzhe , Yang Fan , Shen Chunhua , Yang Jing , Hu Xiaojun , Fei Yingwei
Published: April 2024

Partitioning experiments and the chemistry of iron meteorites indicate that the light element nitrogen could be sequestered into the metallic core of rocky planets during core–mantle differentiation. The thermal conductivity and the mineralogy of the Fe–N system under core conditions could therefore influence the planetary cooling, core crystallization, and evolution of the intrinsic magnetic field of rocky planets. Limited experiments have been conducted to study the thermal properties and phase relations of Fe–N components under planetary core conditions, such as those found in the Moon, Mercury, and Ganymede. In this study, we report results from high-pressure experiments involving electrical resistivity measurements of Fe–N phases at a pressure of 5 GPa and temperatures up to 1400 K. Four Fe–N compositions, including Fe–10%N, Fe–6.4%N, Fe–2%N, and Fe–1%N (by weight percent), were prepared and subjected to recovery experiments at 5 GPa and 1273 K. These experiments show that Fe–10%N and Fe–6.4%N form a single hexagonal close-packed phase (ɛ-nitrides), while Fe–2%N and Fe–1%N exhibit a face-centered cubic structure (γ-Fe). In separate experiments, the resistivity data were collected during the cooling after compressing the starting materials to 5 GPa and heating to ~1400 K. The resistivity of all compositions, similar to the pure γ-Fe, exhibits weak temperature dependence. We found that N has a strong effect on the resistivity of metallic Fe under rocky planetary core conditions compared to other potential light elements such as Si. The temperature-dependence of the resistivity also revealed high-pressure phase transition points in the Fe–N system. A congruent reaction, ε ⇌ γ’, occurs at ~673 K in Fe–6.4%N, which is ~280 K lower than that at ambient pressure. Furthermore, the resistivity data provided constraints on the high-pressure phase boundary of the polymorphic transition, γ ⇌ α, and an eutectoid equilibrium of γ’ ⇌ α + ε. The data, along with the recently reported phase equilibrium experiments at high pressures, enable construction of a phase diagram of the Fe–N binary system at 5 GPa.
Designing Antitrypanosomal and Antileishmanial BODIPY Derivatives: A Computational and In Vitro Assessment
Authors: Gonçalves Raquel C. R. , Teixeira Filipe , Peñalver Pablo , Costa Susana P. G. , Morales Juan C. , Raposo M. Manuela M.
Published: April 2024

Leishmaniasis and Human African trypanosomiasis pose significant public health threats in resource-limited regions, accentuated by the drawbacks of the current antiprotozoal treatments and the lack of approved vaccines. Considering the demand for novel therapeutic drugs, a series of BODIPY derivatives with several functionalizations at the meso, 2 and/or 6 positions of the core were synthesized and characterized. The in vitro activity against Trypanosoma brucei and Leishmania major parasites was carried out alongside a human healthy cell line (MRC-5) to establish selectivity indices (SIs). Notably, the meso-substituted BODIPY, with 1-dimethylaminonaphthalene (1b) and anthracene moiety (1c), were the most active against L. major, displaying IC50 = 4.84 and 5.41 μM, with a 16 and 18-fold selectivity over MRC-5 cells, respectively. In contrast, the mono-formylated analogues 2b and 2c exhibited the highest toxicity (IC50 = 2.84 and 6.17 μM, respectively) and selectivity (SI = 24 and 11, respectively) against T. brucei. Further insights on the activity of these compounds were gathered from molecular docking studies. The results suggest that these BODIPYs act as competitive inhibitors targeting the NADPH/NADP+ linkage site of the pteridine reductase (PR) enzyme. Additionally, these findings unveil a range of quasi-degenerate binding complexes formed between the PRs and the investigated BODIPY derivatives. These results suggest a potential correlation between the anti-parasitic activity and the presence of multiple configurations that block the same site of the enzyme.
Targeting Aging and Longevity with Exogenous Nucleotides (TALENTs): Rationale, Design, and Baseline Characteristics from a Randomized Controlled Trial in Older Adults
Authors: Wang Shuyue , Song Lixia , Fan Rui , Chen Qianqian , You Mei , Cai Meng , Wu Yuxiao , Li Yong , Xu Meihong
Published: April 2024

Nucleotides (NTs), important biomolecules involved in numerous cellular processes, have been proposed as potential candidates for anti-aging interventions. However, whether nucleotides can act as an anti-aging supplement in older adults remains unclear. TALENTs is a randomized, double-blinded, placebo-controlled trial that evaluates the efficacy and safety of NTs as an anti-aging supplement in older adults by exploring the effects of NTs on multiple dimensions of aging in a rigorous scientific setting. Eligible community-dwelling adults aged 60–70 years were randomly assigned equally to two groups: nucleotides intervention group and placebo control group. Comprehensive geriatric health assessments were performed at baseline, 2-months, and 4-months of the intervention. Biological specimens were collected and stored for age-related biomarker testing and multi-omics sequencing. The primary outcome was the change from baseline to 4 months on leukocyte telomere length and DNA methylation age. The secondary aims were the changes in possible mechanisms underlying aging processes (immunity, inflammatory profile, oxidative stress, gene stability, endocrine, metabolism, and cardiovascular function). Other outcomes were changes in physical function, body composition and geriatric health assessment (including sleep quality, cognitive function, fatigue, frailty, and psychology). In the RCT, 301 participants were assessed for eligibility and 122 were enrolled. Participants averaged 65.65 years of age, and were predominately female (67.21%). All baseline characteristics were well-balanced between groups, as expected due to randomization. The majority of participants were pre-frailty and had at least one chronic condition. The mean scores for physical activity, psychological, fatigue and quality of life were within the normal range. However, nearly half of the participants still had room for improvement in cognitive level and sleep quality. This TALENTs trial will represent one of the most comprehensive experimental clinical trials in which supplements are administered to elderly participants. The findings of this study will contribute to our understanding of the anti-aging effects of NTs and provide insights into their potential applications in geriatric healthcare.
Prevalence of and Contributors to Food Insecurity among College Athletes: A Scoping Review
Authors: Pacenta Jamie , Starkoff Brooke E. , Lenz Elizabeth K. , Shearer Amanda
Published: April 2024

Given the financial demands of attending college, the transition to new living situations, abrupt changes in social support, and overall lifestyle adjustments, college students are at an increased risk of food insecurity (FI) compared to the general population. Collegiate athletes experience an even greater risk of FI as a result of greater time commitments and energy demands associated with their sports. This heightened vulnerability poses a tremendous threat to student-athletes’ academic and athletic achievements. This study aims to address the prevalence and primary determinants of FI among collegiate athletes while providing potential solutions to navigate and alleviate the effects of diminished food security among this demographic. To address these aims, a total of 18 articles were selected from both peer-reviewed and gray literature. The U.S. Household Food Security Survey Module (US-HFSSM) survey tools were predominantly utilized across universities throughout the United States to gather data on FI. Student-athletes reported experiencing FI across various regions of the United States, including universities in the northeastern states (n = 5), the southwest region (n = 3), the southeast region (n = 3), the northwest (n = 1), and the Midwest (n = 1). Overall, FI prevalence rates ranged from 9.9% to 65%, and the most significant contributors included limited financial resources, time management, meal plans, and housing location/amenities. These findings highlight a need for screening, education, and interventions to address FI among collegiate athletes.
Correction: Naomi et al. Elateriospermum tapos Yogurt Supplement in Maternal Obese Dams during Pregnancy Modulates the Body Composition of F1 Generation. Nutrients 2023, 15, 1258
Authors: Naomi Ruth , Rusli Rusydatul Nabila Mahmad , Othman Fezah , Balan Santhra Segaran , Abidin Azrina Zainal , Embong Hashim , Teoh Soo Huat , Jasni Azmiza Syawani , Jumidil Siti Hadizah , Matraf Khaled Salem Yaslam Ba , Zakaria Zainul Amiruddin , Bahari Hasnah , Yazid Muhammad Dain
Published: April 2024

After a careful and comprehensive review of our data and the figures in our manuscript, we have identified an area where we believe a correction is warranted in order to enhance the clarity and precision of our findings [...]
Prognostic Nutritional Index and Instant Nutritional Assessement Are Associated with Clinical Outcomes in a Geriatric Cohort of Acutely Inpatients
Authors: Capurso Cristiano , Lo Buglio Aurelio , Bellanti Francesco , Vendemiale Gianluigi
Published: April 2024

Background: Among elderly inpatients, malnutrition is one of the most important predictive factors affecting length of stay (LOS), mortality, and risk of re-hospitalization. Methods: We conducted an observational, retrospective study on a cohort of 2206 acutely inpatients. Serum albumin and lymphocytes were evaluated. Instant Nutritional Assessment (INA) and the Prognostic Nutritional Index (PNI) were calculated to predict in-hospital mortality, LOS, and risk of rehospitalization. Results: An inverse relationship between LOS, serum albumin, and PNI were found. Deceased patients had lower albumin levels, lower PNI values, and third- and fourth-degree INA scores. An accurate predictor of mortality was PNI (AUC = 0.785) after ROC curve analysis; both lower PNI values (HR = 3.56) and third- and fourth-degree INA scores (HR = 3.12) could be independent risk factors for mortality during hospitalization after Cox regression analysis. Moreover, among 309 subjects with a lower PNI value or third- and fourth-class INA, hospitalization was re-hospitalization. Conclusions: PNI and INA are two simple and quick-to-calculate tools that can help in classifying the condition of hospitalized elderly patients also based on their nutritional status, or in assessing their mortality risk. A poor nutritional status at the time of discharge may represent an important risk factor for rehospitalization in the following thirty days. This study confirms the importance of evaluating nutritional status at the time of hospitalization, especially in older patients. This study also confirms the importance for adequate training of doctors and nurses regarding the importance of maintaining a good nutritional status as an integral part of the therapeutic process of hospitalization in acute departments.
Association between Flavonoid Intake and Cognitive Executive Function among African American and White Adults in the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) Study
Authors: Fanelli Kuczmarski Marie , Crawford Sara B. , Sebastian Rhonda S. , Beydoun May A. , Goldman Joseph D. , Moshfegh Alanna J. , Evans Michele K. , Zonderman Alan B.
Published: April 2024

Healthy dietary patterns rich in flavonoids may benefit cognitive performance over time. Among socioeconomically disadvantaged groups, the association between flavonoid intake and measures of cognition is unclear. This study sought to identify associations between flavonoid intake and cognitive performance among Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study participants (n = 1947) across three study visits. Flavonoid intakes were assessed via two 24-h dietary recalls. Cognitive performance was assessed via the Trail Making Test (TMT)-A and TMT-B, which provide measures of attention and executive function, respectively. Mixed effects linear regression was used to model TMT scores over three study visits against visit 1 (v1) flavonoid intake, time (years from v1), and the interaction between v1 flavonoid intake and time, capturing both the cross-sectional association between flavonoid intake and time at v1 as well as the longitudinal association between v1 flavonoid intake and the change in TMT scores over time. Prior to adjustment, inverse cross-sectional associations at v1 were observed between (1) anthocyanidin intake and TMT-A scores for the overall sample and (2) total flavonoid, anthocyanidin, flavan-3-ol, flavone, and flavonol intake and TMT-B scores for the overall sample and among White adults. Only the association between anthocyanidin intake and TMT-B at v1 among White adults persisted after adjustment (for demographic characteristics such as age). One possible explanation for the few significant associations is universally low flavonoid intakes resulting from the consumption of an unhealthy dietary pattern.