bluuebunny/crossref_metadata_2025 huggingface dataset:
Discursos oficiales y políticas nacionales y santafecinas de educación agrotécnica durante la Revolución Argentina (1966-1973)
Authors: D'Ascanio Gabriela Andrea
Published: November 2022

Este artículo se centra en la historia reciente del nivel medio agrotécnico en la provincia de Santa Fe con el propósito de reconocer la interacción de actores, discursos, acciones y agencias estatales que intervinieron en el desarrollo de las escuelas agrotécnicas nacionales y santafesinas, creadas en esa jurisdicción, durante el gobierno de la “Revolución Argentina”. A través del análisis de los discursos de funcionarios estatales, nacionales y provinciales, y de las políticas educacionales que se implementaron en la enseñanza agrotécnica de la provincia de Santa Fe, se procuran develar los alcances y los límites de los mismos en el plano institucional. A la vez se indaga acerca de su vínculo con el desarrollo de las economías regionales, observando la relación de las nuevas instituciones escolares con las actividades económicas propias de las zonas donde se instalaron. El corpus de fuentes analizado se compone de documentos oficiales y de artículos periodísticos de circulación nacional y regional.
Alimentos orgânicos
Authors: Garcia Alane Marília , Bleil Rozane Aparecida Toso , Weber Jucieli
Published: November 2022

O presente estudo procurou conhecer a opinião dos consumidores de um município de pequeno porte da região sudoeste do Paraná em relação aos alimentos orgânicos, buscando identificar os fatores que possam interferir na sua aquisição e no consumo. Utilizou-se como instrumento para coleta de dados um questionário elaborado para este fim a partir de outros estudos já realizados e um questionário socioeconômico. A maioria dos participantes da pesquisa era adulta (86%; n=327), do gênero feminino (77%; n=294), residia na área urbana do município (80%; n=308) e o nível de escolaridade concentrou-se no ensino superior (42%; n=159). Quanto ao conhecimento sobre alimentos orgânicos, 96% (n=368) os entrevistados relataram que conhecem tais alimentos e o critério mais importante para sua aquisição é “fazer bem a saúde” (55%; n=211). Por outro lado, foi destacada a existência de poucos locais para adquirí-los (64%; n= 245), prevalecendo, assim, o baixo consumo pelo grupo (53%; n= 205). A maioria respondeu que confia nas universidades (76%; n= 291) e em profissionais nutricionistas (77%; n= 294) como referência sobre o tema e mais de um terço não confia nas mídias como agentes formadores de opinião (39%; n= 149).  O principal fator que interfere na aquisição e no consumo de orgânicos é a falta de locais destinados à venda dos mesmos, o que restringe o acesso à população.
Study of the Stress-Strain State of the "Bone–Fixation Plate" System in Conjunction With Cortical Tissue Mechanical Properties
Authors: Panchenko Serhii , Kolosov Dmytro , Onyshchenko Serhii , Zub Tetiana , Chechel Taras
Published: November 2022

Background. Bone osteosynthesis is considered one of the most efficient methods of treating fractures of long tubular bones. Deve­lopment of modern computer technology and specialized software makes it possible for a traumatologist to perform preliminary efficiency estimation of osteosynthesis using fixation plates of various designs. Results of such studies can significantly depend on calculation model parameters. In most papers related to the study of a stress-strain state of “bone–fixator” systems, bone tissue is considered as a homogeneous, isotropic, elastic medium. However, in fact it is heterogeneous and has an anisotropy of mechanical characteristics. Accordingly in a case of using a simplified isotropic model of bone tissue, when performing calculations, there is a possibility of obtaining inaccurate results.
Objective. Estimation of influence of orthotropy of the bone tissue physical and mechanical properties on a stress-strain state of the “bone–fixator” system.
Methods. The study is performed in the software environment based on the finite element method. Osteosynthesis of a low transverse fracture of a fibula using a smooth plate is selected as a computational case. Two computational models simplified in terms of geometry are constructed to solve the problem. These models are different only in properties of cortical bone tissue.
Results. Analysis of a stress state in elements of models indicated that normal stresses reached the highest values, and tangential stresses are relatively small. In addition, the character of stress distribution turned out to be significantly inhomogeneous. However, stress state patterns are qualitatively similar for both computational models. A common feature of the maximum stresses both in the bone and in the plate turned out to be that all the maximum stresses are the result of their concentration.
Conclusions. Consideration of orthotropy of elastic parameters of a bone led to significant quantitative changes in the indicators of a stress state. It is established that the minimum safety margins for both models turned out to be considered by the maximum tensile stresses acting in the vertical direction. A similar result in estimating bone strength also occurs in a case when only elastic orthotropy is considered, but the orthotropy of strength indicators is not considered. If the strength orthotropy is considered for the isotropic model of cortical bone, the pattern changes qualitatively. The normal tensile stress directed along the tangent to a circumference of bone cross-section is considered unsafe. Calculations results indicate a possibility of using an isotropic model of cortical tissue when performing comparative estimations in order to identify the most efficient, in terms of strength, fixation plate designs.
The role of the rare books collection in forming the regional cultural space
Authors: Vorobyeva N. V.
Published: November 2022

The article reviews the experience of the Altai Regional Universal Scientific Library named after V. Ya. Shishkov in organizing the system of cultural and educational events to promote book and reading with the use of the Rare Books Department collection.The author gives examples of specific forms and lines of action: exhibitions and excursions; development of digital collections; book studies and research on the history of librarianship and dissemination of book use in the region; implementation of publishing projects; formation of compatriots’ private libraries; cooperation with mass media, and others.Making rare books a part of major library activities: exhibitions, presentations and cultural events helps to extend the library reputation as a custodian of the book heritage and a place of intellectual leisure.Creation of informational resources – electronic collections makes combines the efforts of various organizations and individuals to preserve history and culture and form the image of the region in the global information space. Promotion of rare books in the mass media ensures targeting a wider audience of potential readers.Local history cultural and educational informing is realized through researches, disclosing the history of book existence in the region and books publishing provides an opportunity to access historical sources freely for everyone. Modern approaches to replenishing rare books collections – the formation of personal libraries, studying them and presenting the results in the field of literary and historical research is a significant contribution to the further development of bibliology. The author comes to the conclusion that the library makes active use of the opportunities for disclosing and promoting the rare books collection with the aim of forming the regional cultural space.
Towards a Due Foundation for Image Based Discrimination of Multiple Sclerosis Disease Types Using Magnetic Levitation and Vision Intelligence
Authors: Ramezankhani Milad , Olfatbakhsh Tina , Ashkarran Ali , Abou Zeki Dalia , Radu Irina , Khalighinejad Farnaz , Keihanian Kiandokht , Ionete Carolina , Milani Abbas S. , Mahmoudi Morteza , Pakpour Sepideh
Published: November 2022

The emerging advancements in separation and classification of various biological matters (e.g., living cells and proteins) using magnetic levitation (MagLev) technology have proven to be effective for improving disease diagnostics. MagLev technique has the capacity to detect and separate useful diagnostic biomarkers from biocomplex environments (e.g., blood and plasma), minimizing the unpleasant daunting task of sample preparations and labeling procedures. Here, we demonstrate the capability of this technique combined with image analysis and machine learning approaches for discriminating the various types of multiple sclerosis (MS) as an important model disease. To arrive at a systematic expert system, we combined robust statistical analysis with machine learning to (1) detect and remove outliers from the raw MagLev image datasets; then (2) process the images and output a low dimensional representation of massive data without losing the main statistical features; and finally (3) predict the MS clinical disease type (Relapsing-Remitting, Primary–Progressive, or Secondary–Progressive) using a classifier. This is expected to improve MS diagnostics since the current practices rely solely on clinical observation and central nervous system imaging, making management approaches are often reactional and inefficient. Thus, there is a need to identify the disease type early on. MagLev is expected to improve MS diagnostics, thereby aiding in prognosis and guiding adequate treatment choices before the patient exhibits signs of permanent neurological deficits.
Construction and investigation of the CPP (Cubic Polynomial Projection) method for the transport equation solving
Authors: Astafurov Gleb Olegovich
Published: November 2022

The present paper is devoted to the construction of the (Cubic Polynomial Projection) method for solving the linear transport of neutral particles or unpolarized radiation on tetrahedra. The paper presents and proves estimates for the accuracy of the resulting numerical solution. The absorption coefficient is approximated by a constant value in the cell, the source is a second-degree polynomial in the cell, and the boundary condition is a third-degree polynomial on the faces. Under additional conditions, the method can reach the third order of convergence. The method is based on the characteristic properties of the transport equation, and in some sense, it is a generalization of the CIP (cubic-Interpolation pseudo-particle) method based on Hermitian interpolation in tetrahedra. The success of the method is ensured by the use of projection operators for constructing the scheme instead of the interpolation ones.
PERLAWANAN PEREMPUAN MENGHADAPI PELECEHAN VERBAL
Authors: Rahayu Sinta Dwi , Legowo Martinus
Published: November 2022

Gender inequality is a problem that can be found in countries that adhere to a patriarchal culture. Women become the cornered party in self-defense. The crime of verbal harassment is a threat faced by women. Verbal harassment is not a joke, but a real action that imprints and causes trauma to the victim. Verbal harassment can be said as a disguised crime that attacks the victim's psyche and is not realized by the community for the existence of the impact it causes. This study focuses on the efforts made by women in dealing with verbal abuse. This study uses a qualitative method with a phenomenological theory approach initiated by Hussrl. Data collection techniques used in-depth interviews and literature review to obtain rich and relevant data. Research Results Women are blamed by the community and perpetrators when they fight back during verbal harassment. Women were accused of the clothes they used, in addition, women were accused of not being able to respond to jokes in a relaxed manner. Verbal abuse that occurs in women leaves deep scars, causing a sense of trauma and distrust of others.  

 

Keywords: Verbal Harassment, Resistance, Female

 
Abstrak
Ketimpangan gender menjadi permasalahan yang dapat dijumpai di negara penganut budaya patriarki. Perempuan menjadi pihak yang disudutkan dalam melakukan pembelaan diri. Kejahatan pelecehan verbal menjadi ancaman yang dihadapi perempempuan. Pelecehan verbal bukan merupakan bahan lelulocon, melainkan tindakan nyata yang membekas dan menimbukan traumatis pada korban. Pelecehan verbal dapat dikatakan sebagai kejahatan tersamar yang menyerang psikis korban dan tidak disadari oleh masyarakat atas eksistensi dampak yang ditimbulkan. Penelitian ini berfokus pada upaya yang dilakukan oleh perempuan dalam menghadapi pelecehan verbal. Penelitian ini menggunakan metode kualitatif dengan pendekatan teori fenomenologi yang digagas oleh Hussrl. Teknik pengumpulan data menggunakan wawancara mendalan dan kajian literatur untuk memperoleh data yang kaya dan relevan. Hasil Penelitian Pihak perempuan disalahkan masyarakat dan pelaku ketika melakukan perlawan saat pelecehan verbal. Perempuan dituduh atas pakaian yang mereka gunakan, selain itu perempuan mendapat tuduhan bahwa tidak mampu menanggapi bahan candaan dengan santai. Pelecehan verbal yang terjadi pada prempuan memberikan bekas luka yang mendalam, sehingga menimbulkan rasa traumatis dan ketidakpercayaan pada orang lain.

 

Kata Kunci: Pelecehan verbal, Perlawanan, Perempuan
Pengaruh Kecerdasan Spiritual, Penerapan Akuntansi, Pemahaman Perpajakan Terhadap Kepatuhan WPOP UMKM
Authors: Yohana Masiikah Putri Azmary  , Nuramalia Hasanah  , Nuramalia Hasanah  , Indah Muliasari
Published: November 2022

Penelitian ini bertujuan untuk mengetahui pengaruh variable independen yakni kecerdasan spiritual, penerapan akuntansi UMKM dan pemahaman perpajakan terhadap variable dependen yakni kepatuhan wajib pajak UMKM. Populasi penelitian ini adalah UMKM yang berada di kawasan Pusat Industri Kecil (PIK) Pulogadung, Jakarta Timur. Kepatuhan wajib pajak UMKM diukur dengan kecerdasan spiritual, penerapan akuntansi dan pemahaman perpajakan. Sampe yang diperoleh sebanyak 70 responden dengan metode simple random sampling. Hasil penelitian ini menunjukan bahwa kecerdasan spiritual tidak memiliki pengaruh signifikan terhadap kepatuhan wajib pajak UMKM dan penerpan akuntansi UMKM dan pemahaman perpajakan memiliki pengaruh yang signifikan terhadap kepatuhan wajib pajak.
Faktor - faktor yang Mempengaruhi Kebijakan Dividen
Authors: Mirna Ardiani  , Rida Prihatni  , Dwi Handarini
Published: November 2022

Penelitian ini bertujuan untuk mengetahui pengaruh Profitabilitas (X1), Likuiditas (X2), Leverage (X3), Kepemilikan Institusional (X4) dan Pertumbuhan Perusahaan (X5) terhadap Kebijakan Dividen (Y). Pada penelitian ini menggunakan data sekunder yaitu Laporan Tahunan dan Laporan Keuangan perusahaan Perusahaan Perdagangan, jasa dan Investasi yang terdaftar di Bursa Efek tahun 2016-2018. Dengan teknik pengambilan sampel yaitu metode random sampling dan terpilih 34 perusahaan sebagai sampel dengan total observasi sebesar 102 data. Analisis yang digunakan adalah analisis regresi linier berganda menggunakan software SPSS 26 .Penelitian ini memperoleh hasil sebagai berikut: profitabilitas berpengaruh positif terhadap kebijakan dividen. Pertumbuhan perusahaan berpengaruh negatif terhadap kebijakan dividen Sedangkan, likuiditas, leverage dan kepemilikan institusional tidak berpengaruh terhadap kebijakan dividen.
Pengaruh ROA, Leverage dan Ukuran Perusahaan Terhadap Tax Avoidance Pada Perusahaan Sub-Sektor Otomotif dan Komponen Di BEI Periode Tahun 2012-2018
Authors: Sekar Utami  , Suhono
Published: November 2022

Penelitian ini bertujuan untuk menguji secara empiris pengaruh Return on assets (ROA), Leverage, dan Ukuran Perusahaan terhadap Tax avoidance pada perusahaan manufaktur sub-sektor otomotif dan komponen yang terdaftar di Bursa Efek Indonesia. Teknik pemilihan sampel digunakan purposive sampling, dan diperoleh 8 perusahaan manufaktur sub-sektor otomotif yang memenuhi persyaratan sebagai sampel penelitian. Teknik analisis data yang digunakan dalam penelitian ini adalah analisis regresi linier berganda. Hasil penelitian ini menunjukkan bahwa dari 3 variabel yang diuji, 2 terbukti mempengaruhi tax avoidance yaitu variable ROA, ukuran perusahaan. Sedangkan leverage tidak berpengaruh terhadap tax avoidance.
Pengaruh Financial Distress dan Corporate Governance terhadap Tax Avoidance
Authors: Dinda Yuliana  , Santi Susanti  , Sri Zulaihati
Published: November 2022

Penelitian ini bertujuan untuk menguji pengaruh financial distress dan corporate governance terhadap tax avoidance. Tax avoidance diukur dengan cash effective tax rate, sedangkan financial distress diukur dengan Altman Z-Score, dan corporate governance diproksikan dengan kepemilikan institusional. Metode penelitian yang digunakan adalah metode kuantitatif dengan pendekatan deskriptif statistik. Analisis data menggunakan analisis regresi berganda. Teknik pengambilan sampel yang digunakan adalah simple random sampling yang terdiri dari 40 perusahaan perbankan yang terdaftar di Bursa Efek Indonesia tahun 2018-2019. Hasil penelitian secara parsial menunjukkan bahwa financial distress berpengaruh positif dan signifikan terhadap tax avoidance; corporate governance berpengaruh positif dan signifikan terhadap tax avoidance; serta financial distress dan corporate governance berpengaruh signifikan secara simultan terhadap tax avoidance.
Pengaruh Arus Kas Operasi, Arus Kas Investasi, Arus Kas Pendanaan Terhadap Return Saham Perusahaan Keuangan yang Terdaftar di BEI Periode 2015-2019
Authors: Putri Pratiwi  , I Gusti Ketut Agung Ulupui  , Indah Muliasari
Published: November 2022

Penelitian ini dilakukan untuk memperoleh bukti empiris tentang pengaruh dari arus kas operasi, arus kas investasi, dan arus kas pendanaan terhadap return saham. Penelitian ini menggunakan data sekunder yaitu dengan menggunakan data laporan keuangan perusahaan. Sampel penelitian ini adalah perusahaan sektor keuangan yang terdaftar di BEI periode 2015-2019. Dengan teknik sampling yaitu purposive sampling dan jumlah sampel sebanyak 38 perusahaan. Untuk pengujian hipotesis digunakan analisis regresi linier berganda dengan tingkat signifikansi sebesar 5%. Berdasarkan hasil pengolahan data dapat disimpulkan bahwa arus kas operasi dan arus kas investasi berengaruh positif terhadap return saham. Sementara itu, arus kas pendanaan tidak berpengaruh terhadap return saham. Nilai koefisien determinasi yang diperoleh sebesar 0,197 atau 19,7% yang berarti variabel independent yang digunakan menjelaskan variabel dependent sebesar tersebut. Sementara itu, sisanya sebesar 0,803 atau 80,3% dijelaskan oleh variabel lain yang tidak digunakan pada penelitian ini.
Faktor-Faktor yang Berpengaruh Terhadap Kualitas Pelayanan di Era New-Normal
Authors: Sahnaz Sea Fishabil  , Unggul Purwohedi  , Tri Hesti Utaminingtyas
Published: November 2022

Penelitian ini bertujuan untuk menganalisis pengaruh pengendalian internal, total quality management, kinerja partner, dan citra perusahaan terhadap kualitas pelayanan di era new normal, Penelitian ini menggunakan data primer menggunakan kuesioner. Populasi penelitian ini adalah pengguna aplikasi transportasi dan layanan antar barang online di daerah DKI Jakarta. Teknik pengambilan sampel yang digunakan adalah probability sampling dengan metode simple random sampling. Sampel yang digunakan adalah 100 responden. Metode penelitian yang digunakan yakni regresi linear berganda dan program SPSS 25. Hasil penelitian menunjukkan bahwa pengendalian internal berpengaruh positif dan signifikan terhadap kualitas pelayanan di era new normal. Total quality management berpengaruh positif dan signifikan terhadap kualitas pelayanan di era new normal. Kinerja partner berpengaruh positif dan signifikan terhadap kualitas pelayanan di era new normal. Citra perushaan berpengaruh positif dan signifikan terhadap kualitas pelayanan di era new normal.
The Influence of Net Profit Margin, Dividend Payout Ratio, and Total Asset Turnover on Sharia Share Prices in Jakarta Islamic Index
Authors: Ahmad Wildan Adiansyah Mustafa  , Unggul Purwohedi  , Tri Hesti Utaminingtyas
Published: November 2022

This study was conducted to determine whether there is an effect of using the ratio of NPM, TATO, and DPR on Sharia Stock Prices in the Jakarta Islamic Index during the 2016 – 2019 period with or without the control variable of industry type. The use of this variable aims to describe the condition of the company fundamentally that can affect the price of sharia shares in JII. The type of industry used as the control variable uses the dummy variable method on sharia stock prices in the Jakarta Islamic Index (JII) for the 2016-2019 period. The research method used in this study is quantitative. The selection of research samples using the purposive sampling technique. The results of this study are the net profit margin has no effect on stock prices with or without industrial type control variables, and the dividend payout ratio has no effect on stock prices with or without industrial type control variables. total asset turnover has a positive effect on stock prices with or without industrial type control variables.
Uso de la ecografía como método diagnóstico y terapéutico en la práctica odontológica, una revisión actualizada
Authors:   , Pulgarín Bedoya Liliana María
Published: November 2022

La ecografía es una ayuda diagnóstica en el área de la salud usada para evaluar el desarrollo intrauterino, observar el comportamiento de lesiones, valorar órganos internos y acompañar procedimientos clínicos específicamente en la medicina, pero en la odontología es un campo que apenas se está explorando e incursionando para hacerlo parte de los métodos diagnósticos de rutina en la consulta clínica. El creciente interés de investigar su uso como método diagnóstico y terapéutico en la odontología se precisa en las bondades que tiene y como puede facilitar muchos procesos por ser una ayuda diagnóstica accesible, económica y poco nociva para la salud. En el presente artículo se expone los diferentes usos que se le da a la ecografía en las diferentes especialidades odontológicas y se compara con otros métodos diagnósticos.
Relación entre la conducta alimentaria y la actividad física con la imagen corporal en escolares de primaria de instituciones educativas públicas de Lima Sur en tiempos de COVID-19
Authors:   , Quintanilla Labajos Dasya Antonella
Published: November 2022

Objetivo: Determinar la relación que existe entre la conducta alimentaria y el nivel de actividad física con la imagen corporal en estudiantes de primaria en instituciones educativas públicas de Lima Sur en el confinamiento por COVID- 19. Materiales y métodos: Se realizó un estudio de tipo transversal, observacional y correlacional, en escolares de 1ro y 2do grado de primaria, de tres instituciones educativas públicas (IEP) de educación básica regular escolarizada de Lima Sur. Resultados: Se encuestó a 193 escolares de los grados de 1ro y 2 do de primaria, un 51,3% fueron varones. Al realizar la asociación entre la variable actividad física con la imagen corporal se concluye que existe una alta asociación estadísticamente significativa (p=0,001). Al realizar la asociación entre la variable conducta alimentaria con la imagen corporal se concluye que no hubo diferencias significativas (p=0,05). Conclusiones: Existe una relación significativa entre la imagen corporal y la actividad física (p=0,001), pero no pudo establecer una relación entre la imagen corporal y la conducta alimentaria (p=0,05). Se pudo hallar que está última sí mantiene una asociación con la edad (p=0,01) y el nivel educativo del niño y de la niña (p=0,04).
Relación entre Diabetes Mellitus Tipo II y la Hiperplasia Endometrial en mujeres con hemorragia uterina anormal en el Hospital Nacional Dos de Mayo en el periodo 2014 - 2018
Authors:   , Gutiérrez Gutiérrez Valeria Janette , Cabos Viloria Paola Esther
Published: November 2022

Introducción: Recientes estudios postulan que mujeres con diabetes mellitus tipo 2 tienen mayor riesgo de desarrollar hiperplasia endometrial por el efecto de estimulación celular. El riesgo potencial de progresar a cáncer endometrial depende del tipo de hiperplasia presente, siendo las atípicas las más relacionadas a neoplasia. Objetivos: Determinar la relación entre diabetes mellitus tipo 2 y la hiperplasia endometrial, y describir las características sociodemográficas y clínicas en mujeres que acuden al Hospital Nacional Dos de Mayo (Lima-Perú) por hemorragia uterina anormal. Diseño: Estudio retrospectivo, transversal y analítico. Lugar: Hospital Nacional Dos de Mayo. Participantes: Pacientes mayores de 18 años con hemorragia uterina anormal que cuentan con una biopsia de endometrio en el periodo 2014-2018. Intervenciones: Los datos fueron recolectados y clasificados de las historias clínicas, con la finalidad de ser procesados y analizados en Microsoft Office Excel XP y el programa estadístico SPSS. Para el análisis de datos se empleó la prueba de chi cuadrado, estableciéndose para cada análisis un nivel de significancia de p<0.05. Resultados: Se evidencia que el 44.4% de 117 biopsias endometriales tuvieron un informe anatomopatológico de hiperplasia endometrial. Se obtuvo un OR de 1.3 (IC 95% 0.4 a 3.8; p=0.6) entre la hiperplasia endometrial y diabetes mellitus. Conclusiones: La presencia de diabetes mellitus tipo 2 no se asoció a hiperplasia endometrial en nuestra población de estudio.
Determinación de la frecuencia de Mycoplasma haemofelis mediante tinción Diff Quick en gatos domésticos del Parque Universitario en el distrito de Cercado de Lima
Authors:   , Sassone Moran Andrea
Published: November 2022

El estudio tuvo por objetivo evaluar la frecuencia de Mycoplasma spp. en gatos domésticos del Parque Universitario en el distrito de Cercado de Lima, Perú; mediante el diagnóstico citológico de frotis sanguíneo con tinción Diff Quick. Se recolectaron muestras de sangre de 96 felinos mayores a 6 meses de edad y menores a 4 años. Los frotis de sangre se analizaron mediante citología con tinción Diff Quick a través de un extendido de sangre periférica obtenidos de la punta de la cola para la determinación de positividad a Mycoplasma spp. La frecuencia de micoplasmosis felina en gatos domésticos del parque Universitario es de 41.67 % con ± IC 95%
Efecto de Phyco Terra® bio orgánico en el cultivo de Brassica oleracea y en el suelo degradado en macas, Santa Rosa de Quives, Canta
Authors:   , Sandoval Guevara Javier
Published: November 2022

El valle del río Chillón se presenta alto grado de degradación en suelos, debido al uso indiscriminado de fertilizantes químicos utilizados para mejorar rendimientos, sin evaluar sus efectos ambientales a largo plazo. La presente investigación propone una alternativa sostenible para recuperar suelos degradados, mejorar la producción de hortalizas y sean capaces de competir en el mercado, bridando evidencia del producto Phyco Terra® (Chlorella sp.). Se realizaron cinco tratamientos (C= 0 l.ha-1, T1=2 l.ha-1, T2=4 l.ha-1, T3=6 l.ha-1 y T4=8 l.ha-1) y se evaluaron efectos en el suelo (parámetros físico-químicos y biológicos) y en la Brassica oleracea, además de aspectos económicos (rendimiento agrícola y relación beneficio costo). Se encontró que, para porcentaje de materia orgánica, tratamientos desde 6 l.ha-1 (1.22%) presentaron diferencias, y el de 8 l.ha-1 (1.53%) se recuperó de la degradación. La densidad aparente, porosidad y resistencia a la penetración radicular fueron mayormente influenciados en tratamientos de 6 l.ha-1 y 8 l.ha-1. La respiración basal también fue mayor desde 4 l.ha-1 (12.9 mg/kg.dia-1 C-CO2); no se evidenciaron efectos sostenidos en conductividad eléctrica ni pH. Se observaron efectos en la altura, número de hojas, diámetro de tallo e inflorescencia desde 6 l.ha-1 respecto a los demás tratamientos. El volumen radicular de 6 l.ha-1 (8447.75 cm-3) y 8 l.ha-1 (9860.75 cm-3) presentaron diferencias. Además, hubo diferencias en rendimiento de 8 l.ha-1 (16.49 t.ha-1) y en relación beneficio costo (12.40) respecto a los demás tratamientos. Según los resultados, Phyco Terra® es una alternativa para recuperar suelos, presentando resultados alentadores.
La percepción espacial a través del diseño comercial modular en el nuevo mercado modelo de San Vicente de Cañete
Authors:   , Aguilar Vicente Kevin Luis
Published: November 2022

La arquitectura se fue modificando a lo largo de los años con la aparición de nuevas corrientes, teorías y estilos. Siempre se considera la parte cultural y sensorial de cada uno de los participantes en el contexto o lugar cuando se habla de proyectar. Dado los distintos rubros en los que la arquitectura puede intervenir, el que más relevancia ha tenido al momento de afectar o atender a una considerable cantidad de personas según sus gustos, preferencias y maneras de vivir es el comercial. El mundo se encuentra actualmente en una época de cambio acelerado, con la lucha entre lo local y lo global afectando la relación de las personas con su entorno y con esto, el cambio de la forma de vivir y relacionarse variaría de forma inevitable. Las relaciones interpersonales se reposicionan y adaptan a lugares cuya función original no consideraba este rol, pero que han dado lugar a un nuevo tipo de relación y apego que las representa mejor. En este escenario, los centros comerciales toman protagonismo como una tipología comercial que va más allá del rol con el que fue concebido con el que fueron diseñados y acoge estas nuevas necesidades que adquieren las personas que no las encuentran fuera de él, transformándolos en una especie de nuevos centros de vida urbana. (González, 2015)
Potential of feeding fresh and conserved mulberry leaf in ruminants and its impact on dry matter intake, digestibility, milk production, milk composition and meat quality: A review
Authors: Yue Shuangming , Qiu Shi Xiu , Xu Zhen Ying , Jiao Hao Peng , Tian Mingwu
Published: November 2022

Mulberry (Morus spp.) of Moraceae family is regarded as a unique plant on this earth due to its broader geological distribution across the continents. It is well recognized as alternative feed resources for livestock due to high protein and energy contents as compared to other tree leaves and conventional forages. Furthermore, it can be stored for longer period for livestock in the form of silage and hay. Previous studies have explored that mulberry leaves can be ensiled with or without additive for longer periods without deteriorating quality of silage. Moreover, mulberry leaves had potential to be stored in the form of hay by different techniques. Both mulberry leaves silage and hay influence antioxidant capacity, immunity, milk yield, dry matter intake, nutrient digestibility, and milk and meat composition. This review will explore the potential positive effects of mulberry leaves in fresh and preserved forms on animal’s health and production parameters. Through this review paper, all the important nutritional characteristics of mulberry leaves both fresh and preserved form will prove that it is a novel alternative of conventional fodders or agricultural by products for livestock
On a function maximization in the presence of fuzzy set of constraints with discrete fuzzy parameters
Authors: Mashchenko Serhii O.
Published: November 2022

The present paper investigates a fuzzy mathematical programming problem with a crisp objective function and a fuzzy set of indices of constraint functions with discrete fuzzy parameters. To formalize the set of feasible alternatives, the concept of intersection of fuzzy sets with a fuzzy set of operands is used. The result of this operation is a type-2 fuzzy set (T2FS). It is shown that the T2FS of feasible alternatives can be represented in the form of the collection of T2FSs with constant secondary grades. This approach allows us to define the notion of the weak solution T2FS. The concept of the solution T2FS (not weak) is also proposed. The primary domain of this T2FS is defined as the set of alternatives which together with the corresponding primary degrees of membership form the set of Pareto-optimal pairs to the four-criteria problem. In this problem, the degree of truth of the primary zero degree of membership (which characterizes the infeasibility of the alternative) is minimized in addition to the maximization of the objective function and the degrees (primary and secondary) of membership to the solution T2FS. The notion of a compromise maximizing alternative is given. Several results which enable us to simplify reasoning are obtained. Illustrative examples are given.
Node importance identification for uncertain networks
Authors: Yang Yulin , Li Wanping , Sheng Yuhong
Published: November 2022

This paper proposes the concepts of uncertain strength, uncertain degree, and uncertain clustering coefficient under uncertain networks, along with the proposes uncertain k -shell decomposition algorithm and uncertain h -index. Susceptible-Infected-Recovered (SIR) epidemic model is used to simulate the propagation process under uncertain networks. When compared to with the propagation process under uncertain k -shell decomposition algorithm and uncertain h -index, it is discovered that there are few differences among these methods. In order to find a better node importance identification algorithm, this paper combines these methods using the information entropy to form a new node importance identification method, which is called uncertain entropy method. SIR epidemic model is used to illustrate the difference among these methods.
Scalp acupuncture attenuates brain injury after intracerebral hemorrhage in rats by inhibiting necroptosis
Authors: yao jiayong , Dai Xiaohong , Yu Xueping , Teng Wei , Yu Weiwei , Kuang Binglin , Li Mingyue , Liu Xiaoying , Zheng Lei , Cao Hongtao , Zou Wei
Published: November 2022

Objectives The purpose of this study was to explore the effects and mechanisms of scalp acupuncture on necroptosis and inflammatory injury after intracerebral hemorrhage in rats.
Methods A total of 168 male Sprague–Dawley rats were divided into the sham operation group, intracerebral hemorrhage (ICH) group, scalp acupuncture group, and Nec-1 group. The Garcia score was used to evaluate neurological function. The occurrence of necroptosis after ICH was observed by propidium iodide staining, immunofluorescence co-localization, and transmission electron microscopy. The protein expression of RIP1, RIP3, and MLKL was detected by immunohistochemistry and Western blot analysis, and the levels of TNF-α and IL-1β were determined by enzyme-linked immunosorbent assay. Brain water content was measured by the dry wet weight method.
Results The results showed that scalp acupuncture could alleviate neurologic deficits, inhibit the occurrence of necroptosis, decrease the expression of RIP1, RIP3, and MLKL, reduce the release of TNF-α and IL-1β, and reduce brain edema. This effect was similar to the effect of the necroptosis-specific inhibitor Nec-1.
Conclusion Our study showed that scalp acupuncture may inhibit RIP1/RIP3/MLKL-mediated necroptosis in rats following ICH. In addition, the anti-inflammatory effect and the reduction of brain edema by acupuncture after ICH may be achieved partly through the inhibition of necroptosis.
Statistical Analysis of Modified Whale Optimization Algorithm for Active Power Loss Minimization
Authors: SAHAY SHUVAM , Upputuri Ramanaiah , Kumari Pooja , Kumar Niranjan
Published: November 2022

Optimal reactive power dispatch has an influential impact on improving the power quality of different utilities connected to the power system. It is a non-linear, non-convex, mixed-integer type problem formulated to minimize the active power loss considering generator voltage, tap setting value, and reactive power compensation as a control variable. In this article, a novel modified whale optimization algorithm is applied to solve this problem. A non-linear adaptive weight and an improved golden sign operator are being used to modify the basic whale algorithm. It improves the randomness due to parameter variation and enlarges the search area for accurate global solutions. It prevents the algorithm from local convergence. It also improves the convergence speed as compared to the basic whale optimization algorithm. It is tested and verified on the standard IEEE-57 bus system and IEEE-118 bus system. The solutions given by this method are compared with that of recently developed techniques for proving its dominance over the other techniques. The power losses of the IEEE-57 bus system are reduced to 1.78% and for the IEEE-118 bus system are reduced to 2.66%. Additionally, the comparative statistical analysis is performed in terms of the probability density function and cumulative density function along with the Wilcoxon rank test on the above test systems for 30 independent runs. The statistical analysis results prove that this algorithm is highly efficient in solving this problem compared to other techniques.
GEM-2: Next Generation Molecular Property Prediction Network by Modeling Full-range Many-body Interactions
Authors: Liu Lihang , He Donglong , Fang Xiaomin , Zhang Shanzhuo , Wang Fan , He Jingzhou , Wu Hua
Published: November 2022

Molecular property prediction is a fundamental task in the drug and material industries. Physically, the properties of a molecule are determined by its own electronic structure, which is a quantum many-body system and can be exactly described by the Schrödinger equation. Full-range many-body interactions between electrons have been proven effective in obtaining an accurate solution of the Schrödinger equation by classical computational chemistry methods, although modeling such interactions consumes an expensive computational cost. Meanwhile, deep learning methods have also demonstrated their competence in molecular property prediction tasks. Inspired by the classical computational chemistry methods, we design a novel method, namely GEM-2, which comprehensively considers full-range many-body interactions in molecules. Multiple tracks are utilized to model the full-range interactions between the many-bodies with different orders, and a novel axial attention mechanism is designed to approximate the full-range interaction modeling with much lower computational cost.
Multi-Affinity Network integration based on multi-omics data for tumor Stratification
Authors: Sun Zhensheng , Li Feng , Li Shengjun , Shang Junliang , Liu Jin-Xing , Liu Xikui , Li Yan
Published: November 2022

Tumor stratification facilitates clinical applications such as diagnosis and targeted treatment of patients. Sufficient multi-omics data have facilitated the study of tumor stratification, and many omics fusion methods have been proposed. However, most methods require that the omics data must contain the same samples. In this study, we propose a Multi-Affinity Network integration based on multi-omics data for tumor Stratification, call MANS. MANS addresses the limitation that omics data fusion must contain identical samples. Another novelty is that the subdivision of a single cancer type into a corresponding cancer subtype is unsupervised. Firstly, MANS constructs affinity networks based on the calculated similarity matrices between genes. Then we integrate multi-omics information by performing biased random walks in multiple affinity networks to obtain the neighborhood relationships of genes. Finally, the patient feature is constructed by using the somatic mutation profile. We classify the pan-cancer by lightGBM algorithm with an AUC value of approximately 0.94. The cancer is further subdivided into subtypes by unsupervised clustering algorithm. Among the 12 cancer types, MANS identifies significant differences in patient survival for subtypes of 10 cancer types. In conclusion, MANS is a potent precision oncology tool.
The Impact of Economic Growth, Globalization, and Land Transport Network on CO2 Emissions in Türkiye; Improved Empirical Results
Authors: Aytekin Ibrahim , Yetis Aysegul Demir , Yetis Recep
Published: November 2022

The aim of this study is to examine the effects of transportation activities, which are necessary for economic and commercial development, on greenhouse gas and carbon dioxide (CO2) emissions, and to evaluate changes in CO2emissions from road and rail transportation in Türkiye between 1977 and 2019 according to economic growth and globalization models. In this context, the data were analyzed using stationarity, time series analysis, unit root tests, boxplot, and statistical methods. As a result, it was seen that a very strong positive correlation exists between carbon emissions and economic growth, globalization, railway length, and highway length. The conclusion that all the variables are stationary at the first difference shows that the most suitable model in statistical terms is the Johansen cointegration test model. Accordingly, carbon emissions in Türkiye show that a long-running relationship exists between economic growth, globalization, railway length, and highway length variables. Box charts show that since the 1990s, economic growth, globalization, and increases in both road and railway lengths have directly and proportionally caused increases in carbon emissions. According to the results obtained, considering both environmental health and public health, there is a necessity reducin carbon emissions in order to ensure sustainable development.
Early oral feeding enhanced recovery after intestinal anastomosis in young infants aged less than 3 months -A real-word study
Authors: Lu Changgui , Sun Xinhe , Li Wei , Geng Qiming , Tang Weibing
Published: November 2022

BackgroundEarly oral feeding(EOF) has been proven with a low incidence of complications and fast recovery after surgery in some elective pediatric patients,however,evidence for initiating EOF after intestinal anastomosis(IA) in young infants aged less than 3 months,with immature immune system and organs, is insufficient.This tudy was primary designed to investigate the status and evaluate the feasibility of EOF in young infants with IA in mainland china.Methods491 young infants from 51 hospital in china mainland were divided into two groups(EOF group,n=88;traditional oral feeding,TOF group,n=403),and the clinical characteristics were collected and analyzed for evaluation of the status of EOF in young infants.The complications and recovery were also be compared to defined the feasibility after balancing the baseline by propensity score matching(PSM).ResultsThe time of TPN,PN and postoperative hospital stay were significantly shorter in the EOF group than that in the TOF group in young infants with IA(2.00[1.00,2.00]d vs. 5.00[3.00,6.00]d, p<0.001; 7.00[5.00,8.00]d vs.9.00[7.00,13.00]d, p<0.001;11.00[8.00,14.00]]d vs.14.00[11.00,17.00]d).There were significant differences in the spectrum of disorders, anastomotic sites,operative age and weight between EOF and TOF groups(p=0.002;p=0.029,p=0.045,p<0.001).The overall low rate of EOF in neonates and infants with IA was 17.9%,especially lower in intestinal atresia,stenosis,stoma closure,ileal-colonic,colonic anastomotic site,operative age less than 30 days and weight less than 2.5kg.The overall rate of and Clavien-Dindo II complications were higher in EOF than TOF group(p=0.002),however,no differences were found in severe complications(Clavien-Dindo III/ IV/V).ConclusionThe rate of EOF in young infants with IA is low in Mainland China and the spectrum of disorders,anastomotic sites,operative age and weight maybe factors affecting the performing of EOF. Nevertheless, implementing EOF in young infants with IA maybe beneficial, enhances the recovery, and does not increase the rate of severe complications. This study was registered on Clinical Trials. gov (NCT04464057)
Screening, diagnosis and evaluation of neonatal congenital heart disease in the southernmost region of China
Authors: Chen Qianqian , Zhang Dufei , Wang Yazhou , Zhang Xiangyun
Published: November 2022

Background and aim Early detection,diagnosis and treatment of children with congenital heart disease(CHD) has become a hot research issue.The aim of this study was to establish and promote an appropriate technology system for early screening-diagnosis-evaluation of neonatal CHD in the southernmost region of China--Hainan province.
Methods From January 1,2019 to December 31,2021,all screening staff from the screening institutions use 2 indicators,namely cardiac auscultation plus pulse oximetry(POX),to screen live newborns within 6 to 72 hours after birth.Diagnosis procedure for the screened-positive newborns was performed in the 31 certified medical institutions,and evaluation procedure for the newborns with confirmed CHD was performed in the 6 certified medical institutions.Data of screening,diagnosis,evaluation and treatment were filled in,uploaded and managed online through a neonatal CHD screening information management net.
Results A total of 321,447 live births participated in the CHD screening of this project,providing an overall screening rate of 97.59%(321,447/329,387).And 8,032 cases were screened to be positive.A total of 1099 cases of CHD were confirmed,providing a CHD prevalence of 3.419 per 1000 live births.Atrial septal defect was the most common CHD lesion.The prevalence of insignificant,significant,serious and critical CHD was 1.680,1.260,0.376 and 0.103 per 1000 live births,respectively.The sensitivity of cardiac auscultation,POX and 2 indicators combination(cardiac auscultation plus POX) for CHD detection was 69.15%,33.49% and 91.90%,respectively,and the specificity was 98.36%,99.43% and 97.81%,respectively.The ratio of both positive in 2 indicators in the children with major(serious and critical) CHD at the initial screening was significantly higher than that of single positive in any indicator (χ2=59.455,P<0.001).All children with CHD were evaluated,154 cases of children with major CHD were treated promptly.Only 15 cases of children with major CHD died,the standardized mortality of children aged 0-1 years with CHD was 4.67/100,000,and the case fatality rate of children with major CHD was 9.74%.
Conclusions Cardiac auscultation plus POX for CHD screening is non-invasive,simple,easy to operate and reliable,so that it is conducive to be promoted.It is of great significance to promote an appropriate technology for screening,diagnosis and evaluation of neonatal CHD,for which is conducive to timely diagnose and treat children with CHD,especially children with major CHD.
DHHC2-Mediated AKAP150 Palmitoylation Regulates Hippocampal Synaptic Plasticity and Fear Memory
Authors: Li Meng-Die , Huang Dan-Hong , Zheng Yu-Qi , Tian Dan , OuYang Hui , Song Ke-Xin , Huang Zhen , Lin Xiao-Shan , Zhu Xiao-Qian , Huang Jun-Jie , Wang Si-Ying , Chen Wei-Kai , Yang Shao-Wei , Liu Jian-Min , Xia Zhi-Xuan , Shen Zu-Cheng
Published: November 2022

Background
A-kinase anchoring protein 79/150 (AKAP150) has been suggested to be involved in learning and memory, and synaptic plasticity in the hippocampus is closely associated with memory. However, its effect and underlying mechanisms have not yet been fully elucidated.
Result
Here, we show that there is a significant increase in global and AKAP150 palmitoylation level after high frequency stimulation (HFS). 2-bromopalmitic acid (2-BP), a palmitoylation inhibitor, attenuated the increased palmitoylation level of AKAP150, and abolished the increased interaction between AKAP150 and postsynaptic density protein 95 (PSD-95) induced by HFS. We also found that HFS increased the synaptic expression of protein kinase A (PKA), but not calcineurin (CaN), and the HFS-mediated high affinity binding of PKA to AKAP150 was reversed by 2-BP. Furthermore, the activity of DHHC2, an enzyme responsible for palmitoylation of AKAP150, was upregulated after HFS, and DHHC2 knockdown decreased the level of glutamate receptor 1 phosphorylation at Ser845, as well as induced an impairment of long term potentiation (LTP) in the hippocampus. Importantly, DHHC2 knockdown in the hippocampus impaired the LTP induced by fear conditioning, as well as fear memory.
Conclusion
Our results suggest that DHHC2-mediated AKAP150 palmitoylation plays a critical role in the regulation of hippocampal synaptic plasticity and fear memory.