bluuebunny/crossref_metadata_2025 huggingface dataset:
Transposition of the great arteries: single center experiences
Authors: Soran Türkcan Başak , Yılmaz Mustafa , Özdemir Şahan Yasemin , Ertekin Ömer , Ecevit Ata Niyazi , Atalay Atakan
Published: September 2023

Objectives: Transposition of great arteries is the most common cyanotic congenital heart disease. It is characterized by ventriculoarterial discordance and atrioventricular concordance. The aim of the present study was to review the anatomical and embryological basis of this anomaly and to discuss the surgical outcomes of arterial switch operations. Methods: The study included a total of 61 patients who underwent arterial switch operation. Demographic, anatomical, operative data, duration of stay in intensive care unit, need of postoperative extra corporeal membrane oxigenator, need of delayed sternal closure and mortality rate were retrieved from the institutional databases and medical records. Results: The median age of the patients was 22.9±61.26 (1–455) days, and their weights ranged between 3391.97±686.6 (1900–5500) grams. Transposition of great arteries accompanied intact ventricular septum in 39 patients (63.9%) and ventricular septal defect in 22 patients (36.1%). Coronary arteries were abnormal in 11 patients (18%). Mortality was observed in 7 patients (11.5%) and was seen 5.71±2.98 (1–10) days after surgery. The incidence of coronary anomaly in patients with mortality was 28.6%. The most common coronary anomaly in patients with coronary anomaly with mortality is the anomaly in which the circumflex artery originates from the right coronary artery. Conclusion: Arterial switch operations provide anatomical and complete correction in transposition of great arteries. It can be performed with appropriate timing, good preoperative, peroperative and postoperative management with low mortality. Coronary artery anomaly is not a contraindication for arterial switch operations, and with the detailed and careful evaluation of the appropriate coronary artery anatomy, transpositions with coronary anomalies are often uneventful.
Kecerdasan Sosial Dalam Pendidikan Islam; Analisis Gagasan Fikih Sosial KH. MA. Sahal Mahfudh
Authors: Prasetia Senata Adi , Fahmi Muhammad , Faizin Moh.
Published: September 2023

Artikel ini membahas bagaimana pengembangan kecerdasan sosial dalam pendidikan Islam dan relevansinya di era kontemporer perspektif KH. Sahal Mahfudh. Sebagai makhluk sosial, manusia tidak bisa hidup sendiri dan selalu memerlukan orang lain untuk berinteraksi. Atas dasar itu, pengembangan kecerdasan sosial dalam pendidikan Islam sangat dibutuhkan. Artikel ini berargumen bahwa pengembangan kecerdasan sosial dalam pendidikan Islam di bawah bimbingan KH. MA. Sahal Mahfudh lebih menitikberatkan pada aspek kecerdasan sosial yang tercakup dalam gagasan fikih sosial. Melalui penelitian kualitatif-eksploratif dan kepustakaan, serta dokumentasi dan pengayaan literatur serta analisis data menggunakan tiga aspek; kondensasi data, display data dan verifikasi data, hasil temuan menunjukkan bahwa gagasan fikih sosial KH. MA. Sahal Mahfudh menjadi basis utama bagi pengembangan kecerdasan sosial peserta didik. Dalam hal ini, perkembangan kecerdasan sosial ditampilkan melalui kepekaan sosial, wawasan sosial, dan komunikasi sosial. Melalui pendidikan yang terfokus pada sensitivitas sosial, pengetahuan sosial, dan komunikasi sosial, Kiai Sahal telah menciptakan landasan yang kuat guna pengembangan aspek kecerdasan sosial dalam konteks pendidikan Islam di Indonesia. Bentuk konkret pengembangan kecerdasan sosial yang dilakukan Kiai Sahal tercermin dalam rumusan pendidikan intelektual, pendidikan sosial kemasyarakatan, pendidikan organisasi, pendidikan olahraga dan kesehatan, serta pendidikan keterampilan. Penerapan pemikiran fikih sosial Kiai Sahal dalam pendidikan Islam hendaknya menjadi model dan paradigma baru dalam mengembangkan kecerdasan sosial pada peserta didik pada pendidikan Islam Indonesia kontemporer.
Membela petani kecil: Pelaksanaan Land Reform pada masa pemerintahan Presiden Sukarno (1960-1966)
Authors: Awat Darwin , Aji Sampurno Silverio R.L.
Published: September 2023

Tanah merupakan sumber yang sangat vital dan aset strategis dalam kehidupan masyarakat yang sebagian besar penduduknya adalah petani. Hal ini tidak saja berlaku bagi rakyat Indonesia, akan tetapi bagi masyarakat di seluruh dunia. Tanah sendiri di dalam hubungannya dengan kehidupan manusia mempunyai peranan yang sangat penting. Dari sisi ekonomi tanah merupakan sarana produksi yang dapat mendatangkan kesejahteraan. Dari sisi sosial dan politis, tanah dapat menentukan posisi seseorang dalam pengambilan keputusan dan menentukan tinggi rendahnya status sosial pemiliknya.
Principles of organization and implementation of internal financial control of State (municipal) institutions
Authors: ENDOVITSKII Dmitrii A. , POZHIDAEVA Tat'yana A. , SPIRIDONOVA Natal'ya E.
Published: September 2023

Subject. This article discusses the issues related to the definition of the principles of internal financial control of State (municipal) institutions as the basic provisions of its implementation and organization.
Objectives. The article aims to substantiate the composition and define the principles of organization and implementation of internal financial control of State (municipal) institutions, the implementation of which in control activities provides conditions for effective management of institutions.
Methods. For the study, we used detailing, observation, generalization, comparison, classification, grouping, etc.
Results. Based on the results of a comparative analysis of the distinctive features of internal financial control of State (municipal) institutions from the external one, the article systematizes the well-known approaches to determining the principles of control activities. This helped identify a set of principles of internal financial control of State (municipal) institutions, which form the basis for its effective organization and implementation.
Conclusions. The article concludes that there are differences in the composition of the principles of external and internal control, which are associated with the distinctive features of their organization and implementation. The results obtained contribute to the development of theoretical, organizational and methodological provisions of internal financial control.
La legitimación de los partidos políticos en la sentencia del Tribunal Supremo 1294/2021, de 2 de noviembre de 2021
Authors: Gómez Díaz Ana Belén
Published: September 2023

UNA VERSIÓN ONLINEFIRST DE ESTE TRABAJO SE PUBLICÓ POR ERROR EN LA SECCIÓN DE COMUNICACIONES Y COMENTARIOS JURISPRUDENCIALES EL 29-06-2023. EL 05-10-2026 SE ACTUALIZO A SU SECCIÓN REAL, ARTÍCULOS.
El presente trabajo aborda el estudio de la legitimación activa de los partidos políticos partiendo del análisis de la Sentencia de la Sala Tercera (Sección 4.ª) del Tribunal Supremo 1294/2021, de 2 de noviembre, que inadmitió, por falta de legitimación, el recurso contencioso-administrativo interpuesto por el Partido Popular contra el Real Decreto de nombramiento de Fiscal General del Estado. El trabajo pone de manifiesto la discrepancia existente en el seno de la Sala Tercera del Tribunal Supremo sobre la cuestión objeto de estudio, en la que subyacen cuestiones de esencial trascendencia jurídica, tanto desde el punto de vista dogmático como práctico: el derecho a la tutela judicial efectiva; la necesidad de no permitir la creación de zonas inmunes al control jurisdiccional; la defensa de los intereses colectivos, públicos y del interés general. Estas cuestiones nucleares del Derecho administrativo deben cohonestarse con la necesidad de no convertir a la Justicia en un foro de discusión política, diluyendo su verdadera esencia. El trabajo, por último, reflexiona sobre la «solución» que, al respecto de la legitimación activa de los partidos políticos, debe dar la Sala y en el que parece estar más dividida: los recursos planteados contra los indultos concedidos a los condenados en el «juicio del procés».
PERBANDINGAN METODE REVISED DISTRIBUTION DAN IMPROVED ZERO POINT METHOD UNTUK MENGOPTIMALKAN BIAYA PENDISTRIBUSIAN BARANG (Studi kasus: UMKM Kue Bolu Pak Agus di Kabupaten Kayong Utara)
Authors: Junaidi Junaidi , Kifitiah Mariatul , Pasaribu Meliana
Published: September 2023

Metode transportasi adalah suatu metode yang dapat digunakan untuk menentukan pengalokasian barang dari suatu sumber ke suatu tujuan tertentu dengan biaya seminimal mungkin. Penelitian ini dilakukan pada UMKM kue bolu Pak Agus di Kabupaten Kayong Utara. UMKM ini memiliki tiga pabrik produksi dan delapan agen. Jarak antara tempat produksi dan agen tersebut memiliki variasi jarak yang berpengaruh terhadap biaya pendistribusian. Apabila rute pendistribusian yang digunakan tidak optimal maka biaya pedistribusian yang dikeluarkan tentu lebih besar. Oleh karena itu diperlukan suatu metode transportasi yang dapat mengoptimalkan rute pendistribusian sekaligus meminimalkan biaya pendistribusian. Metode Revised Distribution (RDI) dan Improved Zero Point Method (IZPM) merupakan metode yang dapat langsung memberikan solusi optimal tanpa harus mencari solusi awal. Kedua metode tersebut dibandingkan dari segi efektifitas dan efisiensi, metode mana yang memberikan solusi paling optimal dengan jumlah iterasi minimum. Langkah awal yang dilakukan adalah menyusun formulasi masalah, kemudian membuat tabel transportasi, setelah itu menentukan solusi optimal dengan menggunakan metode RDI dan IZPM. Berdasarkan hasil penelitian yang dilakukan, dari segi efektifitas kedua metode tersebut mendapatkan solusi optimal yang sama, yaitu sebesar Rp 224.500,00. Namun untuk segi efisiensi, metode RDI membutuhkan delapan kali iterasi dan IZPM membutuhkan tiga kali iterasi. Dengan demikian metode IZPM lebih efisien dalam permasalahan ini
Dual FGFR-targeting and pH-activable Smart Ruthenium-Peptide Conjugates for targeted therapy of Breast Cancer
Authors: Franco Machado João , Sá Marco , Pires Inês , Silva Miguel , Marques Fernanda , A. S. Coelho Jaime , Mendes Filipa , M. Piedade M. Fátima , Machuqueiro Miguel , Angeles Jiménez María , Garcia Maria Helena , Correia João D. G. , Morais Tânia
Published: September 2023

Dysregulation of Fibroblast Growth Factor Receptors (FGFRs) signaling has been associated with breast cancer, yet employing FGFR-targeted delivery systems to improve cytotoxic agents is still sparsely exploited. Herein, we report four new bi-functional ruthenium-peptide conjugates (RuPCs) with FGFR-targeting and pH-dependent releasing abilities, envisioning the selective delivery of cytotoxic Ru complexes to FGFR(+)-breast cancer cells, upon specific accumulation and controlled activation at the acidic tumoral microenvironment. The antiproliferative potential of the RuPCs and active Ru complexes was evaluated in four breast cancer cell lines with different FGFR expression levels (SK-BR-3, MDA-MB-134-VI, MCF-7, and MDA-MB-231) and in the normal human dermal fibroblasts (HDF) cell line, at pH 6.8 and 7.4 that mimics the tumor microenvironment and normal tissues/bloodstream, respectively. The RuPCs showed higher cytotoxicity in cells with higher level of FGFR expression at acidic pH. Additionally, RuPCs showed up to 6-fold higher activity in the FGFR(+) breast cancer lines compared to the normal line. The release profile of Ru complexes from RuPCs corroborates the antiproliferative effects observed. Remarkably, the cytotoxicity and releasing ability of RuPCs were shown to be strongly dependent on the peptide conjugation position in the Ru complex. Complementary molecular dynamic simulations and computational calculations were performed to help interpret these findings at the molecular level. In summary, we identified a lead bi-functional RuPC that holds strong potential as a FGFR-targeted chemotherapeutic agent.
Bottom-illuminated photothermal nanoscale chemical imaging with a flat silicon ATR in air and liquid
Authors: Ramer Georg , Yilmaz Ufuk , Sam Savda , Lendl Bernhard
Published: September 2023

We demonstrate a novel approach for bottom-illuminated atomic force microscopy infrared spectroscopy (AFM-IR). This nearfield technique is suitable for AFM-IR measurements in liquids, taking advantage of an attenuated total reflection (ATR) setup where the developing evanescent wave is used for photothermal excitation of the sample of interest. Conventional bottom-illuminated measurements are conducted using high-refractive index prisms. We showcase the advancement of instrumentation through the introduction of novel, flat silicon substrates as replacements for prisms. We illustrate the feasibility of this technique for bottom illuminated AFM-IR in both, air and liquid. We also show how modern rapid prototyping technologies enable commercial AFM-IR instrumentations to accept these new substrates. This new methodic approach paves the way for a wide range of experiments since virtually any established protocol for Si surface functionalization can be applied to this sample carrier and the low unit cost enables rapid iteration of experiments.
Enantioselective Aziridination of Unactivated Terminal Alkenes Using a Planar Chiral Rh(III) Indenyl Catalyst
Authors: Gross Patrick , Im Hoyoung , Laws David , Park Bohyun , Baik Mu-Hyun , Blakey Simon
Published: September 2023

Chiral aziridines are important structural motifs found in natural products and various important target molecules. They serve as versatile building blocks for the synthesizing chiral amines. While advances in catalyst design have enabled robust methods for enantioselective aziridination of activated olefins, simple and abundant alkyl substituted olefins pose a significant challenge. In this work, we introduce a novel approach utilizing a planar chiral rhodium indenyl catalyst to facilitate the enantioselective aziridination of unactivated alkenes. This transformation exhibits a remarkable degree of functional group tolerance and displays excellent chemoselectivity favoring unactivated alkenes over activated counterparts, delivering a wide range enantioenriched high value chiral aziridines. Computational studies unveil a stepwise aziridination mechanism in which alkene migratory insertion plays a central role. This process results in the formation of a strained four-membered metallocycle and serves as both the enantio- and rate-determining step in the overall reaction.
Sustainability and Outreach in the Microfinance Sector of Ghana
Authors: Bansah Esther Dzifa , Adjei Raymond Kofi
Published: September 2023

The recent finance sector clean-up in Ghana led to the collapse of a number of microfinance institutions (MFIs), which reignited the discussion of whether MFIs can achieve much-needed financial sustainability while also meeting the goal of reaching out to the poor. In that regard, this paper explores the potential for MFIs to improve the breadth of outreach by fostering financial inclusion and to deepen the depth of outreach by targeting the poor while simultaneously pursuing self-sufficiency and profitability. Using data from the MIX database for 89 MFIs over a 20-year period, we employed fixed and random effects models to show that among other results, outreach is improved when MFIs are financed more by debt than equity and that the pursuit of profitability is a disincentive to outreach. Overall, the results suggest that with improved efficiency in the pursuit of sustainability, MFIs in Ghana stand better chances of achieving outreach both in depth and breadth.
Re-Examining the South African Reserve Bank’s Policy Reaction Function Using the NARDL Model
Authors: Phiri Andrew
Published: September 2023

The 3–6 percent inflation target is a policy rule used by the South African Reserve Bank (SARB) to fulfil its statutory obligation of ensuring a low and stable inflation environment and its policy reaction function assesses how the Reserve Bank responds to deviations of inflation from its target. We rely on nonlinear autoregressive distributive lag (NARDL) models to estimate the asymmetric preferences which the Reserve Bank has to inflation deviations during rising and falling episodes of inflation. Using quarterly data spanning from 2002:q1 to 2021:q4, we estimate the policy reaction functions using 7 disaggregated measures of inflation to capture the heterogeneity in the formation of price expectations. We further segregate our data into two sub-periods, corresponding to the pre-crisis and post-crisis era, as a robustness exercise. Overall, our findings indicate that in the post-crisis era the SARB (i) has become more responsive to inflation, output fluctuations and exchange rates and (ii) has responded more aggressively to rising inflation than falling inflation.
The role of international trade in the globalized world
Authors: Mboungou Mouyabi Seke
Published: September 2023

The role of international trade in the globalized world has been the consequence of many studies in various issues. It is a strategic activity exercised by a country in the development process of improving its economy. Moreover, international trade discusses primarily the exchange of goods and services across the perimeter of a country. Multinational corporations play an important role in the development of international trade, among other aspects such as globalization and outsourcing. Due to international trade, various sectors of domestic economy can change drastically. Against this plethora of competitive advantage provided by international trade, what is its role in the globalized world today? It is important, however, to clarify the lantern of readers in highlighting the difference between keywords. International trade is the main element of global integration promoted by economists and business leaders of our century. Globalized world is the growing interdependence of countries momentous from the aggregate integration of trade, finance, people, and ideas in one global marketplace.
Marketing strategies of impulsive buying in grocery shopping among consumers in nagercoil city
Authors: Jannah  , J. Ferusha Pearl
Published: September 2023

In a rapidly evolving economy, people thrive to raise their standards of living and improve their quality of life by refining their purchasing behaviors, which marketers try to understand and make an effort to enhance their shopping experience. Although impulsive buying may seem to be a common tendency among customers, it is a brilliant technique that marketers tend to deduce and exploit to take the best advantage. This study focuses on comprehending the theme of impulsive buying and what marketing strategies influence such unplanned purchases with respect to grocery shopping. Data for this study were collected from grocery shoppers in Nagercoil City. The primary and secondary data collection techniques were the two sources used in this study. The data obtained from the consumers were analyzed using statistical tools and software. SPSS software was used for the analysis of the research data. For this study, total of 100 samples were collected from both genders of various age group consumers from Nagercoil City selected through a non-probability sampling technique called Convenience Sampling.
Digital marketing in the food service industry in india: A review
Authors: Asha Devi J. , Chandrasekar K. S.
Published: September 2023

Every organization has adopted digital technologies and innovations to attract customers. Social media plays a significant role in marketing the products of every organization. In that platform, an extensive audience is likely to be customers, and they can be part of business development and advancement. Organizations must acquire and attract new customers through social media marketing. Social media is a powerful platform for capturing customer attention towards a product. Business owners can fix their weaknesses based on customer feedback from social media accounts. Persons who view the advertisements or marketing strategies of products write reviews based on their preferences. The owners can consider their feedback and make changes according to the review to improve their business. Social media offers many opportunities to promote businesses. Many social media platforms are available, but some are best known for their tools and techniques, making them valuable for promoting business. It is clear that restaurants have started shifting their marketing budget towards online ads on social media platforms and aggregators to rank better. This study focuses on identifying the effectiveness of digital marketing in India's food service industry.
Purchase behaviour of mobile phones among women consumers in kanyakumari district
Authors: Kasthuri S. , J. Ferusha Pearl
Published: September 2023

The main objective of this study is to analyze consumer buying behavior for mobile phones in Kanyakumari District. Both primary and secondary data were extensively used in this study. In this study, secondary data on various topics were collected from various Journals, books, websites and newspapers. Primary data were collected through a questionnaire from the respondents, who are female consumers in Kanyakumari District. For this study, 120 respondents were selected, and a simple random sampling method was used to select the samples from the total number of female mobile phone consumers in Kanyakumari District. This study concludes that companies need to study the psychology of women's purchase patterns and adapt their marketing strategies to attract female customers. Even among women, there are many segments such as job holders, housewives and students, who have very different needs and expectations from their mobile phones. This study helps understand the purchase behavior of mobile phones among female consumers.
TAC1 Gene Therapy in the Gut to Reduce Long-Term Memory Loss in Tg4-42 Alzheimer Diseased Mice: A Research Proposal
Authors: Pereira Tyler
Published: September 2023

Alzheimer’s disease (AD) is a neurodegenerative disorder that mainly affects a large percentage of the older adult population. AD can cause many problems, most notably long-term memory (LTM) loss. Many studies have observed a decreased level of substance P (SP) in the hippocampus of individuals with AD. In this paper, we propose a novel strategy to limit AD-related decline of LTM using probiotics transformed with SP. These transformed bacteria will contain varying concentrations of SP and will be injected into three different segments of the proximal colon in AD mouse models. LTM will be measured through Morris Water Maze (MWM) and Barnes Maze (BM) tests over three months to examine improvements in spatial memory. It is anticipated that this experiment will demonstrate that increased concentrations of SP in the proximal colon will result in the greatest reduction in LTM loss in AD individuals. This experiment will establish a new therapeutic option for AD individuals to slow the progression of LTM loss.
A Study Of Public-Private Partnerships Through The Public Value Lens: Case Study Of Transport Infrastructure Provision In Vietnam
Authors:   , Dao Hoa
Published: September 2023

Engaging private actors in public service delivery, Public-Private Partnerships (PPPs) represent a growing set of public policies to many governments worldwide. A rich and diverse literature has reviewed their performance across many countries and in different sectors. This study provides an evaluation of PPPs through a public value framework using the case of transport infrastructure provision in Vietnam. It addresses the following research question: What is the public value created through PPPs in Vietnam transport infrastructure provision? The contribution of PPPs to public value creation is examined in terms of four aspects: achievement of outcomes, service delivery, trust and legitimacy, and the effectiveness of public organisations. Data was collected from three implemented PPP projects, including a road user survey, secondary documents, and interviews with public officials and private employees working for partners of PPP/BOT projects. The quantitative and qualitative results are triangulated to explore the value of the projects from all relevant perspectives.

The operationalisation of the public value framework allows the study to highlight the perspectives of users on PPP performance. The study finds that the public value creation of PPPs is generally rated low by users across the four aspects of public value creation while the stakeholders’ perceptions of PPP performance are various and sometimes inconsistent. The study also demonstrates the need to integrate the public value paradigm into the policy-making process, which also requires situating users and payers vis-à-vis public management mechanisms such as PPPs.

The study contributes to the PPP literature by providing an evaluation of PPP implementation in a context of a developing country through the public value lens. Besides, the study provides a case of how the public value concept can be operationalised into a framework to evaluate a public policy with empirical evidence. Implications are anticipated for public agencies in the engagement with PPP mechanism.
Observation on Curative Effect of Minimally Invasive Osteotomy Combined with Ilizarov Technique in the Treatment of Knee Osteoarthritis with Varus Deformity
Authors: Di Yong , Wu Guohua , Zhang Guangpu , Guo Xiaoyu , Li Liqing
Published: September 2023

This paper aims to analyze the clinical efficacy of minimally invasive osteotomy combined with Ilizarov technique in the treatment of knee osteoarthritis with varus deformity. 80 patients with knee osteoarthritis and varus deformity who were treated in our hospital from January 2022 to May 2023 were selected, all of whom were affected by one knee. They were randomly divided into groups, including the study group and the control group, each with 40 patients. Patients in the control group were treated with fibula-tibial osteotomy and internal fixation, and patients in the study group were treated with minimally invasive osteotomy combined with Ilizarov technique. The operation time of the patients in the study group was significantly longer than that of the control group (P < 0.05). The intraoperative blood loss of the patients in the study group was significantly more than that of the control group (P < 0.05). The hospitalization expenses of the patients in the study group were significantly more than those of the control group (P < 0.05). The postoperative femorotibial angle and mechanical axis offset distance in the study group were significantly smaller than those in the control group (P < 0.05). The postoperative New York Hospital for Special Surgery (HSS) scores of the study group were significantly higher than those of the control group (P < 0.05). The postoperative visual analogue scale (VAS) score of the study group was significantly lower than that of the control group (P < 0.05). The range of motion of the knee joint in the study group was significantly greater than that in the control group (P < 0.05). The incidence of tendon injury, infection, and nerve injury in the study group (2.50%) was significantly lower than that in the control group (30.00%) (P < 0.05). Minimally invasive osteotomy combined with Ilizarov technique can be applied in the treatment of knee osteoarthritis with varus deformity, although the operation time is longer, with more intraoperative blood loss and higher treatment cost, but it has no effect on the femorotibial angle and mechanical axis deviation of the patient. It can significantly improve the movement distance, knee joint function, and knee joint range of motion, and significantly reduce the postoperative pain of patients, reduce the incidence of complications, and thus has high clinical application value.
Clinical Efficacy of Traditional Chinese Medicine Orthopedic in the Treatment of Senile Osteoarthritis
Authors: Chen Wenguang
Published: September 2023

Objective: This paper aims to explore and analyze the clinical effect of traditional Chinese medicine (TCM) orthopedic treatment on elderly patients with osteoarthritis. Methods: The study period is from January 2021 to June 2023. 62 elderly patients with osteoarthritis admitted to our hospital were selected and divided into the study group (n = 31) and the control group (n = 31) using the random number table scheme. The patients in the control group were treated with conventional Western medicine acemetacin, and the patients in the study group were treated with traditional Chinese medicine orthopedic. The treatment options included manual massage, traditional Chinese medicine fumigation, and oral administration of traditional Chinese medicine. The clinical effective rate, osteoarthritis function Japanese Orthopedic Association score (JOA), visual analogue pain score (VAS), and incidence of adverse reactions were compared between the two groups. Results: The clinical effective rate of patients in the study group was higher than that of the control group (P < 0.05), the JOA score of the patients in the study group was higher than that of the control group after treatment (P < 0.05), while the VAS score of the patients in the study group was lower than that of the control group after treatment (P < 0.05). Plus, the incidence of adverse reactions in the study group was lower than that in the control group (P < 0.05). Conclusions: TCM orthopedic treatment for elderly patients with osteoarthritis has a significant effect, it can improve joint function, relieve pain, with a low incidence of adverse reactions, which can be widely applied in clinical practice.
Clinical Efficacy and Safety Analysis of 308nm Excimer Ultraviolet Light Combined with Carbon Dioxide Fractional Laser in the Treatment of Refractory Vitiligo
Authors: Li Gang
Published: September 2023

This paper aims to explore the clinical effect and safety of combined application of 308 nm excimer ultravioletlight and carbon dioxide fractional laser in the treatment of refractory vitiligo. The study was carried out from January 2020 to December 2022. 60 patients with refractory vitiligo were selected and divided into the study group (n = 30) and the control group (n = 30) through the lottery method of medical record envelopes. The patients in the control group were treated with 308 nm excimer ultraviolet light, and the patients in the study group were treated with 308 nm excimer ultraviolet light combined with carbon dioxide fractional laser treatment. The clinical effective rate, leukoplakia area, IgG level, and incidence of adverse reactions were compared between the two groups. The clinical effective rate of the study group was higher than that of the control group (P < 0.05). After treatment, the leukoplakia area of the study group was lower than that of the control group (P < 0.05), and the IgG level of the study group was lower than that of the control group (P < 0.05). The incidence of adverse reactions in the study group was lower than that in the control group (P < 0.05). The combined application of 308 nm excimer ultraviolet light and carbon dioxide fractional laser therapy for patients with refractory vitiligo has a significant effect, can reduce the area of leukoplakia and IgG levels, and has high treatment safety, which can be widely applied in clinical practice.
Effect of Ultrasound-Guided Transversus Abdominis Plane Block Combined with Lornoxicam on Pain and Recovery Quality After Abdominal Surgery in Patients with Drug Addiction
Authors: Luo Ling , Yang Zhouxu , Yang Hongtao
Published: September 2023

Objective: This paper aims to analyze the analgesic effect of ultrasound-guided transversus abdominis plane block (TAPB) combined with non-steroidal anti-inflammatory analgesic drug lornoxicam on abdominal surgery in patients with a history of drug addiction. Methods: 32 patients aged 18–60 who underwent lower abdominal surgery in the First People’s Hospital of Liangshan Yi Autonomous Prefecture and Butuo County People’s Hospital of Liangshan Yi Autonomous Prefecture from January 2022 to March 2023 were selected, the patients must have drug abuse history for more than 1 year, with a history of drug withdrawal and relapse. The patients were divided into observation group and control group by the envelope method, with 16 cases in the observation group and 16 cases in the control group. Two groups of patients underwent ultrasound-guided bilateral transversus abdominis plane block after the operation. The observation group was treated with dexmedetomidine hydrochloride 1μg/kg + 0.25% ropivacaine hydrochloride 40ml, and the control group was treated with 40ml 0.9% sodium chloride injection, the two groups of patients returned to the ward after operation and given intravenous infusion of lornoxicam for relieving the pain. The visual analogue scale(VAS) score of postoperative pain, the times of rescue analgesia, the time of postoperative anal exhaust, the time of ambulation, nausea and vomiting, withdrawal symptoms, related adverse reactions, and hospitalization days were compared between the two groups. Results: The VAS score of postoperative pain in the observation group was significantly lower than that in the control group, P < 0.05. Patients in the observation group used less postoperative rescue analgesics than those in the control group, P < 0.05. For postoperative anal exhaust time, the difference between the two groups of patients was relatively small, and the time in the observation group was shorter, P > 0.05. The time to get out of bed and the length of hospital stay were not significantly different between the control group and the observation group, P > 0.05. The withdrawal symptoms of the patients in the observation group were better, P < 0.05, nausea and vomiting, and other adverse reactions were lower in the control group, P < 0.05. Conclusion: Ultrasound-guided transversus abdominis plane block combined with lornoxicam can be used to relieve pain in abdominal surgery for patients with drug addiction, which can effectively improve the therapeutic effect of patients and reduce the number of postoperative rescue analgesia. Thus, it has high clinical application value.
Clinical Study on Treatment of Chronic Prostatitis with Lingze Tablets Combined with TCM Herbal Acupoint Plasters
Authors: Tian Hongfei , You Chuanjing
Published: September 2023

Objective: To study the therapeutic effect of Lingze tablets combined with traditional Chinese medicine herbalacupoint plasters on chronic prostatitis. Methods: A total of 64 patients with chronic prostatitis who were admitted to the Andrology Clinic of Shuyang County Hospital of Traditional Chinese Medicine from March 2021 to March 2023 were randomly divided into a treatment group and a control group, with 32 cases in each group. The control group took Lingze tablets orally, 4 tablets/time, 3 times/d; the treatment group took the same medication along with traditional Chinese medicine acupoint herbal plasters. The two groups of patients were treated continuously for 6 weeks, and the differences in the relevant indexes of the curative effect were observed. Results: The NIH-Chronic Prostatitis Symptom Index (NIH-CPSI) scores of the two groups significantly reduced after treatment (P < 0.05), and the scores of the patients in the treatment group were lower than those in the control group (P < 0.05). The treatment received in the treatment group achieved and efficacy of 96.88%, which was significantly higher than that of the group, which was 81.25% (P < 0.05). The maximum flow rate (MFR), average flow rate AFR, and urine output of the patients of both groups improved significantly after treatment (P < 0.05). However, the experimental group showed better improvements in these indicators (P < 0.05). Conclusion: Lingze tablets combined with traditional Chinese medicine acupoint herbal plasters can significantly improve the symptoms and urodynamic function of patients with chronic prostatitis.
A Case Study of Severe QT Interval Prolongation Caused by Antidepressants
Authors: Fang Chao , Xiao Nuan , Zhao Hongmei , Ren Simin , Tan Lili , Wu Jiannan
Published: September 2023

QT interval prolongation can be categorized into primary and secondary types according to its etiology. In this paper, we report a case of severe asymptomatic QT interval prolongation secondary to antidepressants. Regular follow-up and electrocardiogram monitoring is crucial when applying antidepressants, especially for patients without cardiac symptoms. This article presents case studies and examines existing literature on long QT syndrome to enhance the diagnosis and management of QT interval prolongation. This is especially relevant for non-psychiatric healthcare professionals who need to be attentive to the side effects of antidepressants to prevent potential adverse consequences resulting from oversight.
Comparison of Emergency Management Strategies for Nosocomial Infections Between Two Earthquakes
Authors: Li Xi-xi , He Mei , Wang Dong , Wang Hai-Yan , Pu Jia
Published: September 2023

Aim: Based on the experience of the 5.12 Wenchuan Earthquake and the 8.8 Jiuzhaigou Earthquake, the emergency management strategies for nosocomial infections were compared between the two earthquakes. The experience shared in the present study provides a guideline for the emergency medical rescue of future earthquake. Methods: The patients involved in this study were those injured in the earthquake and admitted to the hospital for treatment. As an earthquake relief center, the hospital participated in the emergency rescue work of the two recent major earthquakes in western China. Review analysis was carried out in the hospital’s infection control experience adopted in the two major earthquakes. It was emphasized that, targeting the characteristics and difficulties in the prevention and control of nosocomial infection, different innovative infection control emergency strategies were adopted by the frontline disaster relief hospitals, under the special circumstances and medical conditions in an earthquake disaster. Results: According to the different focus of infection control in the two earthquakes, different hospital infection control strategies were adopted, and the incidence of nosocomial infections was effectively controlled.
Assessment of Calf Skeletal Muscle Stiffness in Diabetic Nephropathy Patients with Medial Tibial Stress Syndrome by Two-Dimensional Shear Wave Elastography
Authors: Wang Lei , Ran Lei
Published: September 2023

Objective: To explore the feasibility of two-dimensional shear wave elastography in evaluating calf skeletal muscle stiffness in diabetic nephropathy patients with medial tibial stress syndrome. Methods: A total of 48 diabetic nephropathy patients with medial tibial stress syndrome from January 2020 to December 2022 were included as the study group, and 48 patients with diabetic nephropathy during the same period were included as the control group. Both groups were detected by two-dimensional shear wave elastography with ultrasonic equipment, and Young‘s modulus of the tibialis anterior muscle, tibialis posterior muscle, and gastrocnemius muscle were observed and analyzed in the two groups. Results: The Young‘s modulus values of tibialis anterior muscle, tibialis posterior muscle, and gastrocnemius muscle in the study group were significantly lower than those in the control group (P < 0.05). Conclusion: Two-dimensional shear wave elastography is feasible for the evaluation of calf skeletal muscle stiffness in diabetic nephropathy patients with medial tibial stress syndrome, and has high accuracy and repeatability. This technique can be used to diagnose, treat and monitor muscle lesions in patients with diabetic nephropathy, and can also be used to assess muscle fatigue and exercise capacity, which has broad application prospects.
Impact of Sarcopenia on Prognosis in Frail Elderly Patients with Chronic Kidney Disease
Authors: Ran Lei , Wang Lei , Cai Tingting
Published: September 2023

Objective: To investigate the impact of sarcopenia on the prognosis of frail elderly patients with chronic kidney disease. Methods: A total of 98 elderly frail patients with chronic kidney disease were included in this study from June 2020 to July 2022. The patients were randomly divided into a study group of 48 cases and a control group of 50 cases. The control group only received conventional treatment for chronic kidney disease. On the basis of conventional treatment for chronic kidney disease, the study group added sarcopenia intervention treatment. The quality-of-life scores, muscle mass and muscle strength, renal function, and incidence of complications of the two groups were observed and analyzed. Results: The quality-of-life score, muscle mass and muscle strength, and renal function of the study group were significantly better than those of the control group (P < 0.05); the incidence of complications in the study group was 12.5%, which was significantly lower than that of the control group 36% of the group (P < 0.05). Conclusion: There is a close relationship between sarcopenia and frail elderly patients with chronic kidney disease. Sarcopenia will further aggravate the frailty symptoms and increase the risk of complications in elderly patients with chronic kidney disease. For elderly patients with chronic kidney disease, sarcopenia should be screened and intervened as early as possible to improve the prognosis and quality of life of the patients.
Observation on the Clinical Effect of Emergency Interventional Therapy on Acute Severe Non- Variceal Upper Gastrointestinal Bleeding
Authors: Chen Bo , Shi Donghong , Ai Min , Zhang Longjiang
Published: September 2023

Objective: To observe the clinical effect of emergency interventional therapy for patients with acute severe non-variceal upper gastrointestinal bleeding. Methods: 78 patients with acute severe non-variceal upper gastrointestinal bleeding who were treated in the General Hospital of the Eastern Theater Command from May 2020 to May 2023 were randomly divided into two groups according to different treatment plans. The study group underwent emergency upper gastrointestinal angiography and interventional embolization therapy, the control group was treated with esomeprazole; the clinical data related to the two groups were compared, including the total effective rate of treatment, blood pressure stabilization time, bleeding control time, etc. Results: The effective rate of clinical treatment in the study group was 97.44%, which was higher than that in the control group, which was 79.49% (P < 0.05). Both were significantly shorter (P < 0.05); the 7 d rebleeding rate and 30 d rebleeding rate of the study group were lower than those of the control group (P < 0.05); the 7 d and 30 d mortality rates of the two groups after treatment were compared, and the comparative study group was lower, but there was no significant difference (P > 0.05). Conclusion: Emergency interventional therapy can control bleeding more quickly, shorten bleeding control time and complete hemostasis time, shorten blood pressure stabilization time and abdominal pain relief time, and reduce rebleeding rate in patients with acute severe non-variceal upper gastrointestinal bleeding.
الجهود الدولية في مكافحة الاتجار بالبشر (الجزء الثاني)
Authors: Yahya Mata Mohammad
Published: September 2023

شَكَّل هذا الكتاب الجزء الثاني من الإصدار العلمي "الجهود الدولية في مكافحة الاتجار بالبشر" الذي شكل الإصدار رقم (467) جزأه الأول. وضم هذا الكتاب البحوث التالية التي استكملت الموضوعات المتعلقة بظاهرة الاتجار بالبشر:
• موقف التربية الإسلامية من الاتجار بالنساء والأطفال ونقل الأعضاء البشرية/ د. محمد فضل عبد العزيز المراد. تناول هذا البحث موضوع الاتجار بالأطفال والنساء باعتباره مشكلة تستحق البحث وتدعو إلى معرفة حجمها وموقف الشريعة الإسلامية منها والعقوبة التي يجب إنزالها على مرتكبيها، ومعرفة سبل الوقاية من الوقوع فيها.
• تجريم الاتجار بالنساء واستغلالهن في الشريعة الإسلامية/ د. محمد عبد الله ولد محمدن. تناول هذا البحث أربعة محاور تناول من خلالها موقف الشريعة الإسلامية من الاتجار بالمرأة واستغلالها.
• موقف الشريعة الإسلامية من نقل الأعضاء بين البشر/ د. محمد المدني بوساق، وتناول هذا البحث موضوع حكم نقل الأعضاء بين البشر في الشريعة الإسلامية.
• نماذج عربية في مواجهة الاتجار في الأشخاص؛ وقد عرض هذا البحث القانون العربي النموذجي لمواجهة جرائم الاتجار بالأشخاص، وعرض مواده بالتفصيل.
• مشروع أولي بشأن إعلان حقوق الإنسان لدول مجلس التعاون لدول الخليج العربية، وعرض هذا البحث مواد المشروع الأولي بشأن إعلان حقوق الإنسان لدول مجلس التعاون لدول الخليج العربية.
• مشروع النظام (القانون) الموحد لمكافحة الاتجار بالأشخاص لدول مجلس التعاون، وعرض هذا البحث الصيغة التي أعدتها لجنة الخبراء المتخصصين في اجتماعها المنعقد في مقر الأمانة العامة لمجلس التعاون الخليجي بالرياض خلال الفترة من 19-21 صفر 1427هـ(الموافق 19-21 مارس 2006م).
• مناقشة حول الاتجار بالأشخاص بغرض الدعارة: استغلال جنسي أم اختيار شخصي ومسألة طلب، وهذا البحث من إعداد لجنة وضع المرأة التابعة للمجلس الاقتصادي والاجتماعي بالأمم المتحدة في الدورة التاسعة والأربعين.
• الاتجار في الأطفال (تجنيد الأطفال في النزاعات المسلحة، الدعارة، السياحة الجنسية، التبني غير المشروع). وتناول هذا البحث موضوع الاتجار في الأطفال في إطار اتفاقية حقوق الأطفال وموقفها من أنواع الاتجار في الأطفال المذكورة سابقًا.
• الاتجار في الأشخاص لغرض العمل القسري، في إطار مؤتمر العمل الدولي.
Utilizing geographic information system and indexing to evaluate irrigation suitability of groundwater in Kalihati Upazila, Bangladesh
Authors: Islam Md. Touhidul , Das Nilima , Jahan Nusrat , Siddik Md. Sifat , Mahmud Khalid , Adham A.K.M.
Published: September 2023

The aim of this research was to evaluate groundwater quality for irrigation in Kalihati Upazila, Bangladesh, a region that is significantly reliant on groundwater for crop development, especially during dry periods. By combining hydrochemical analysis and Geographic Information System (GIS), the research examined the physicochemical attributes and their spatial distribution. Fifteen groundwater samples from various locations were analyzed to measure parameters such as sodium adsorption ratio (SAR), soluble sodium percentage (SSP), residual sodium carbonate (RSC), magnesium adsorption ratio (MAR), electrical conductivity (EC), total dissolved solids (TDS), total hardness (TH), Kelly's ratio (KR), permeability index (PI), and potential salinity (PS). The pH of the groundwater ranged between 5.51 and 7.53, indicating slightly acidic to moderately alkaline conditions suited for irrigation. The EC ranged between 115.7 and 458 μS/cm, mostly falling into the "excellent" or "good" categories. Groundwater displayed irrigation suitability with TDS below 182 ppm and low SAR values, but variable RSC and MAR values indicated localized water quality issues. Based on the irrigation water quality index, all samples were within the "permissible" range. However, GIS-generated maps showed disparities in groundwater quality across the study area. Correlation matrices revealed significant links between various factors. Both the Piper and Gibbs diagrams displayed a prevalent Ca-HCO3 groundwater type influenced by geological formations. Overall, the study confirmed groundwater's appropriateness for irrigation while recommending periodic evaluations due to a few uncertainties. In conclusion, the study found that hydrochemical analysis, GIS mapping, and correlation matrices reveal groundwater quality and spatial trends, allowing for sustainable water resource management and agricultural advancement.