bluuebunny/crossref_metadata_2025 huggingface dataset:
Quantification of chemical–polymer surface interactions in microfluidic cell culture devices
Authors: Xu Hui , Shuler Michael L.
Published: April 2009

Microfluidic cell culture devices have been used for drug development, chemical analysis, and environmental pollutant detection. Because of the decreased fluid volume and increased surface area to volume ratio, interactions between device surfaces and the fluid is a key element that affects the performance and detection accuracy of microfluidic devices, particularly if fluid is recirculated by a peristaltic pump. However, this issue has not been studied in detail in a microfluidic cell culture environment. In this study, chemical loss and contaminant leakage from various polymer surfaces in a microfluidic setup were characterized. The effects of hydrophilic coating with Poly (vinyl alcohol), Pluronic® F‐68, and multi‐layer ionic coating were measured. We observed significant surface adsorption of estradiol, doxorubicin, and verapamil with PharMed® BPT tubing, whereas PTFE/BPT and stainless steel/BPT hybrid tubing caused less chemical loss in proportion to the fraction of BPT tubing in the hybrid system. Contaminants leaching out of the BPT tubing were found to be estrogen receptor agonists as determined by estrogen‐induced green fluorescence expression in an estrogen responsive Ishikawa cell line and also caused interference with an estradiol enzyme‐linked immunosorbent assay (ELISA) assay. Stainless steel/BPT hybrid tubing caused the least interference with ELISA. In summary, polymer surface and chemical interactions inside microfluidic systems should not be neglected and require careful investigations when results from a microfluidic system are compared with results from a macroscale cell culture setup. © 2009 American Institute of Chemical Engineers Biotechnol. Prog., 2009
Minerals as Molecules—Use of Aqueous Oxide and Hydroxide Clusters to Understand Geochemical Reactions
Authors: Casey William H. , Rustad James R. , Spiccia Leone
Published: April 2009

Large aqueous oxide ions as minerals! Minerals dissolve by repeated ligand exchange reactions and geochemists use polyoxometalate ions to establish structure–reactivity relations for environmentally important functional groups. Here, for example, are plotted the dissolution rates of two classes of minerals against rates of solvent exchanges around the corresponding aquo ions.

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Geochemists and environmental chemists make predictions about the fate of chemicals in the shallow earth over enormously long times. Key to these predictions is an understanding of the hydrolytic and complexation reactions at oxide mineral surfaces that are difficult to probe spectroscopically. These minerals are usually oxides with repeated structural motifs, like silicate or aluminosilicate polymers, and they expose a relatively simple set of functional groups to solution. The geochemical community is at the forefront of efforts to describe the surface reactivities of these interfacial functional groups and some insights are being acquired by using small oligomeric oxide molecules as experimental models. These small nanometer‐size clusters are not minerals, but their solution structures and properties are better resolved than for minerals and calculations are relatively well constrained. The primary experimental data are simple rates of steady oxygen‐isotope exchanges into the structures as a function of solution composition that can be related to theoretical results. There are only a few classes of large oxide ions for which data have been acquired and here we review examples and illustrate the general approach, which also derives directly from the use of model clusters to understand for the active core of metalloenzymes in biochemistry.
ChemInform Abstract: Phase Stability and Thermophysical Properties of Neodymium Cerium Composite Oxide.
Authors: Zhong Xinghua , Xu Zhenhua , Zhang Yanfei , Zhang Jiangfeng , Cao Xueqiang
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structure and High‐Temperature Thermoelectric Properties of SrAl2Si2.
Authors: Kauzlarich Susan M. , Condron Cathie L. , Wassei Jonathan K. , Ikeda Teruyuki , Snyder G. Jeffrey
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Coupled Spin Ordering in the Ln2LiRuO6 Double Perovskites.
Authors: Makowski Sophia J. , Rodgers Jennifer A. , Henry Paul F. , Attfield J. Paul , Bos Jan‐Willem G.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Hexagonal TmMn6Sn4Ge2 Investigation by Neutron Diffraction and 119Sn Moessbauer Spectroscopy.
Authors: Perry Laura K. , Ryan D. H. , Venturini G. , Malaman B.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Bis[2‐(2‐hydroxyethyl)pyridinium] μ‐Decavanadato‐bis[pentaaquamanganate(II)] Tetrahydrate.
Authors: Klistincova Lenka , Rakovsky Erik , Schwendt Peter
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: High‐Pressure, High‐Temperature Single‐Crystal Growth, ab initio Electronic Structure Calculations, and Equation of State of ε‐Fe3N1+x.
Authors: Niewa Rainer , Rau Dieter , Wosylus Aron , Meier Katrin , Hanfland Michael , Wessel Michael , Dronskowski Richard , Dzivenko Dmytro A. , Riedel Ralf , Schwarz Ulrich
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Gold Catalyzed Reactions with Cyclopropenes.
Authors: Bauer Juergen T. , Hadfield Maximillian S. , Lee Ai‐Lan
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Doping Effect of Fluorinated Aromatic Hydrocarbon Solvents on the Performance of Common Olefin Metathesis Catalysts: Application in the Preparation of Biologically Active Compounds.
Authors: Samojlowicz Cezary , Bieniek Michal , Zarecki Andrzej , Kadyrov Renat , Grela Karol
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Strategy for Targeting of Photosensitizers. Synthesis of Glycodendrimeric Phenylporphyrins, Incorporation into a Liposome Membrane and Interaction with a Specific Lectin.
Authors: Ballut Severine , Makky Ali , Loock Bernard , Michel Jean‐Philippe , Maillard Philippe , Rosilio Veronique
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Are Allenes with Zwitterionic Character Still Allenes? Of Course!
Authors: Lavallo Vincent , Dyker C. Adam , Donnadieu Bruno , Bertrand Guy
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Asymmetric Allylation of Aliphatic Aldehydes by Chiral Bipyridine N,N′‐Dioxides.
Authors: Hrdina Radim , Boyd Thomas , Valterova Irena , Hodacova Jana , Kotora Martin
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Dispersed Ruthenium Hydroxide Supported on Titanium Oxide Effective for Liquid‐Phase Hydrogen‐Transfer Reactions.
Authors: Yamaguchi Kazuya , Koike Takeshi , Kim Jung Won , Ogasawara Yoshiyuki , Mizuno Noritaka
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Direct‐Type Substitution Reaction of α‐Alkyl Enolates: A Pd/Broensted Base Catalyzed Approach to the Decarboxylation Allylation of Sulfonylimidates.
Authors: Kan S. B. Jennifer , Matsubara Ryosuke , Berthiol Florian , Kobayashi Shu
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Assembly of Functionalized α‐Hydroxy Carbonyl Compounds via Combination of N‐Heterocyclic Carbene and Pd Catalysts.
Authors: He Jinmei , Tang Shibing , Tang Shouchu , Liu Jian , Sun Yongquan , Pan Xinfu , She Xuegong
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Properties of the anti and syn Isomers of Dibenzothieno[b,d]pyrrole.
Authors: Liu Yunqi , et al. et al.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mn(OAc)3‐Promoted Regioselective Free Radical Thiocyanation of Indoles and Anilines.
Authors: Pan Xiang‐Qiang , Lei Mao‐Yi , Zou Jian‐Ping , Zhang Wei
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Oxidative Pd(II)‐Catalyzed C—H Bond Amination to Carbazole at Ambient Temperature.
Authors: Jordan‐Hore James A. , Johansson Carin C. C. , Gulias Moises , Beck Elizabeth M. , Gaunt Matthew J.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel Synthesis of 1,3,5‐Trisubstituted Pyrazoles Through a Spiro‐pyrazoline Intermediate via a Tandem 1,3‐Dipolar Cycloaddition/Elimination.
Authors: Dadiboyena Sureshbabu , Valente Edward J. , Hamme Ashton T. II
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Characterization of a New Series of Hydroxy Pyrazolines.
Authors: Parveen Humaira , Iqbal Prince Firdoos , Azam Amir
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Novel Anthraquinone Derivatives: Synthesis via Click Chemistry Approach and Their Induction of Apoptosis in BGC Gastric Cancer Cells via Reactive Oxygen Species(ROS)‐Dependent Mitochondrial Pathway.
Authors: Wang Shaoru , Wang Qilong , Wang Yan , Liu Lin , Weng Xiaocheng , Li Guorui , Zhang Xiaolian , Zhou Xiang
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Aldol‐Type Reaction of a 4‐Pyrone: A Straightforward Approach to 4‐Pyrone‐Containing Natural Products.
Authors: Sengoku Tetsuya , Takemura Takuma , Fukasawa Emi , Hayakawa Ichiro , Kigoshi Hideo
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Electrochemical Synthesis of 4‐(Dihydroxyphenylthio)‐2H‐chromen‐2‐one Derivatives.
Authors: Nematollahi Davood , Azizian Javad , Sargordan‐Arani Mohsen , Hesari Mahdi , Jameh‐Bozorghi Saeed , Alizadeh Abdolhamid , Fotouhi Lida , Mirza Behrooz
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Synthesis of Benzo[b]acridones.
Authors: Seixas Raquel S. G. R. , Silva Artur M. S. , Pinto Diana C. G. A. , Cavaleiro Jose A. S.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Clean Synthesis and Antibacterial Activities of Spiro[pyrimido[4,5‐b]quinoline‐5,5′‐pyrrolo [2,3‐d]pyrimidine]‐pentaones.
Authors: Ghahremanzadeh Ramin , Azimi Seyyedeh Cobra , Gholami Nader , Bazgir Ayoob
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Efficient Copper‐Catalyzed Cascade Synthesis of Quinazoline and Quinazolinone Derivatives.
Authors: Huang Cheng , Fu Yuan , Fu Hua , Jiang Yuyang , Zhao Yufen
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 2,5,8‐Tri‐tert‐butyl‐1,3,4,6,7,9‐hexaazaphenalene: Synthesis, Crystal Structure and Calculation of Homolytic N—H Bond Dissociation Enthalpies.
Authors: Jiang Yuqin , Zhang Huaqiang , Wan Xiangjian , Xue Xiaosong , Liu Yuanhai , Song Haibin , Yu Ao , Chen Yongsheng
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: First Asymmetric Total Synthesis of Penarolide Sulfate A1.
Authors: Mohapatra Debendra K. , Bhattasali Debabrata , Gurjar Mukund K. , Khan M. Islam , Shashidhara K. S.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Addition of Selenium Dibromide to Divinyl Sulfide: Spontaneous Rearrangement of 2,6‐Dibromo‐1,4‐thiaselenane to 5‐Bromo‐2‐bromomethyl‐1,3‐thiaselenolane.
Authors: Amosova Svetlana V. , Penzik Maxim V. , Albanov Alexander I. , Potapov Vladimir A.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis, Structure Analysis and Cytotoxicity Studies of Novel Unsymmetrically N,N′‐Substituted Ureas from Dehydroabietic Acid.
Authors: Rao Xiaoping , Song Zhanqian , He Ling , Jia Weihong
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Coagulanolide, a Withanolide from Withania coagulans Fruits and Antihyperglycemic Activity.
Authors: Maurya Rakesh , Akanksha Akanksha , Jayendra Jayendra , Singh Amar B. , Srivastava Arvind K.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Calmodulin Inhibitory Activity of the Malbrancheamides and Various Analogues.
Authors: Miller Kenneth A. , Figueroa Mario , Valente Meriah W. N. , Greshock Thomas J. , Mata Rachel , Williams Robert M.
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Xestosaprol C, a New Pentacyclic Hydroquinone Sulfate from a Marine Sponge Xestospongia sapra.
Authors: Kubota Takaaki , Kon Yuji , Kobayashi Jun'ichi
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Secure Route to the Epoxybicyclo[7.3.0]dodecadienediyne Core of the Kedarcidin Chromophore.
Authors: Ogawa Kouki , Koyama Yasuhito , Ohashi Isao , Sato Itaru , Hirama Masahiro
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of (‐)‐Spirangien A and Its Methyl Ester.
Authors: Paterson Ian , Findlay Alison D. , Noti Christian
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Common Pharmacophore Identification Using Frequent Clique Detection Algorithm.
Authors: Podolyan Yevgeniy , Karypis George
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Virtual Screening and Prediction of Site of Metabolism for Cytochrome P450 1A2 Ligands.
Authors: Vasanthanathan Poongavanam , Hritz Jozef , Tabourneau Olivier , Olsen Lars , Joergensen Flemming Steen , Vermeulen Nico P. E. , Oostenbrink Chris
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Tautomer Enumeration and Stability Prediction for Virtual Screening on Large Chemical Databases.
Authors: Milletti Francesca , Storchi Loriano , Sforna Gianluca , Cross Simon , Cruciani Gabriele
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Elucidating Isoniazid Resistance Using Molecular Modeling.
Authors: Wahab Habibah A. , Choong Yee‐Siew , Ibrahim Pazilah , Sadikun Amirin , Scior Thomas
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Low Temperature Precursor Route for Highly Efficient Spherically Shaped LED‐Phosphors M2Si5N8:Eu2+ (M: Eu, Sr, Ba).
Authors: Zeuner Martin , Hintze Frauke , Schnick Wolfgang
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemical Vapor Deposition of Ru Thin Films with an Enhanced Morphology, Thermal Stability, and Electrical Properties Using a RuO4 Precursor.
Authors: Han Jeong Hwan , Lee Sang Woon , Choi Gyu‐Jin , Lee Sang Young , Hwang Cheol Seong , Dussarrat Christian , Gatineau Julien
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Succinyl Hydroxamates as Potent and Selective Non‐peptidic Inhibitors of Procollagen C‐Proteinase: Design, Synthesis and Evaluation as Topically Applied, Dermal anti‐Scarring Agents.
Authors: Bailey Simon , Fish Paul V. , Billotte Stephane , Bordner Jon , Greiling Doris , James Kim , McElroy Andrew , Mills James E. , Reed Charlotte , Webster Robert
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Trinuclear Metallacycles: Metallatriangles and Much More
Authors: Zangrando Ennio , Casanova Massimo , Alessio Enzo
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Molecular Recognition, Fluorescence Sensing, and Biological Assay of Phosphate Anion Derivatives Using Artificial Zn(II)—Dpa Complexes
Authors: Sakamoto Takashi , Ojida Akio , Hamachi Itaru
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Water in Stereoselective Organocatalytic Reactions
Authors: Gruttadauria Michelangelo , Giacalone Francesco , Noto Renato
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Transition Metals in Organic Synthesis. Part 89. Synthesis of Biologically Active Carbazole Alkaloids Using Selective Transition‐Metal‐Catalyzed Coupling Reactions
Authors: Knoelker Hans‐Joachim
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of (+)‐Allocyathin B2, (‐)‐Erinacine B, and (‐)‐Erinacine E
Authors: Watanabe Hideaki , Takano Masashi , Nakada Masahisa
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Damage Detection and Base Flipping in Direct DNA Alkylation Repair
Authors: Yang Cai‐Guang , Garcia Kristel , He Chuan
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Evaluation of Biological Influence of Nanomaterials Using Toxicokinetic and Toxicoproteomic Approach
Authors: Yoshikawa Tomoaki , Nabeshi Hiromi , Yoshioka Yasuo
Published: April 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Early change in defence mechanisms and coping in short‐term dynamic psychotherapy: Relations with symptoms and alliance
Authors: Kramer Ueli , De Roten Yves , Michel Luc , Despland Jean‐Nicholas
Published: April 2009

Several patient‐related variables have already been investigated as predictors of change in psychodynamic psychotherapy. Defensive functioning is one of them. However, few studies have investigated adaptational processes, encompassing defence mechanisms and coping, from an integrative or comparative viewpoint. This study includes 32 patients, mainly diagnosed with adjustment disorder and undergoing time‐limited psychodynamic psychotherapy lasting up to 40 sessions, and will focus on early change in defence and coping. Observer‐rater methodology was applied to the transcripts of two sessions of the first part of the psychotherapeutic process. It is assumed that the contextual–relational variable of therapeutic alliance intervenes as moderator on change in adaptational processes. Results corroborated the hypothesis, but only for coping, whereas for defences, overall functioning remained stable over the first 20 sessions of psychotherapy. These results are discussed within the framework of disentangling processes underlying adaptation, i.e., related to issues on trait and state aspects, as well as the role of the therapeutic alliance. Copyright © 2009 John Wiley & Sons, Ltd.
Flow cytometric investigation of neutrophil oxidative burst and apoptosis in physiological and pathological situations
Authors: Elbim Carole , Lizard Gérard
Published: April 2009

Flow cytometric analysis provides a rapid screen for abnormalities of polymorphonuclear neutrophils (PMN) function and reflect their behavior in vivo more accurately. This review summarizes the major fluorescent probes used to study PMN oxidative burst and apoptosis using flow cytometry (FCM). We also provide examples of FCM studies in physiological and pathological situations, illustrating the advantages of FCM for assessment of PMN oxidative burst and PMN apoptosis. These data point to the role of FCM in detecting primary immunodeficiencies such as IRAK4 deficiency and support the use of the assessment of the PMN oxidative burst for routine testing in patients with bacterial infections. We also demonstrate the utility of whole‐blood analysis using FCM for a better understanding of PMN functionality, i.e., tuning PMN responses to inflammatory stimuli. Finally, FCM permits a simultaneous analysis of phenotypic, functional and morphometric parameters assessing whole‐blood PMN apoptosis, in particular in response to Toll‐like receptor agonists and during simian immunodeficiency virus infection. © 2009 International Society for Advancement of Cytometry
A simple three‐party password‐based key exchange protocol
Authors: Huang Hui‐Feng
Published: April 2009

In three‐party password‐based key exchange (3PAKE) protocol, a client is allowed to share a human‐memorable password with a trusted server such that two clients can agree on a secret session key for secure connectivity. Recently, many 3PAKE protocols have been developed. However, not all of them can simultaneously achieve security and efficiency. Without any server's public key, this article will propose a simple three‐party password‐based authenticated key exchange scheme. Compared with the existing schemes, the proposed scheme is not only more efficient, but also is secure. Copyright © 2009 John Wiley & Sons, Ltd.
Analysis of soft handoff algorithm for multi‐cellular systems: A finite integral approach
Authors: Chandra Aniruddha , Roy Sanjay Dhar
Published: April 2009

In this paper the performance of soft handoff algorithm based on pilot signal strength measurements has been studied. In connection with the soft handoff it has been observed that the existing analytic expressions often involve integration in infinite limits. The expressions containing such kind of integrals have been meticulously transformed into finite range equations. Probability of outage, number of base stations (BS) in the active set, and number of active set updates are some of the performance metrics commonly considered in soft handoff. Accurate closed forms for all these performance indicators have been computed which, in turn, simplifies the calculation of several other metrics entailing them. Moreover, the underlying system model takes into account of more than two BS (specifically three) extending the traditional two BS model toward more complex but realistic characterization of soft handoff performance analysis framework. Copyright © 2009 John Wiley & Sons, Ltd.
Validity of particle‐counting method using laser‐light scattering for detecting platelet aggregation in diabetic patients
Authors: Nakadate Hiromichi , Sekizuka Eiichi , Minamitani Haruyuki
Published: April 2009

We aimed to study the validity of a new analytical approach that reflected the phase from platelet activation to the formation of small platelet aggregates. We hoped that this new approach would enable us to use the particle‐counting method with laser‐light scattering to measure platelet aggregation in healthy controls and in diabetic patients without complications. We measured agonist‐induced platelet aggregation for 10 min. Agonist was added to the platelet‐rich plasma 1 min after measurement started. We compared the total scattered light intensity from small aggregates over a 10‐min period (established analytical approach) and at over a 2‐min period from 1 to 3 min after measurement started (new analytical approach). We found that platelet aggregation in diabetics with HbAlc ≥ 6.5% was significantly greater than in healthy controls by both analytical approaches. However, platelet aggregation in diabetics with HbAlc < 6.5%—patients in the early stages of diabetes—was significantly greater than in healthy controls only by the new analytical approach, not by the established analytical approach. These results suggest that platelet aggregation as detected by the particle‐counting method using laser‐light scattering could be applied in clinical examinations by our new analytical approach. © 2009 Wiley Periodicals, Inc. Electron Comm Jpn, 92(3): 1–8, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/ecj.10057
Colored Supramolecular Host System Using a Charge‐Transfer Complex Composed of 1,1′‐Bi‐2‐naphthol and 2,5‐Substituted 1,4‐Benzoquinone
Authors: Imai Yoshitane , Kamon Kensaku , Kinuta Takafumi , Sato Tomohiro , Tajima Nobuo , Kuroda Reiko , Matsubara Yoshio
Published: April 2009

A colored, two‐component, supramolecular, host system has been developed. This supramolecular host system uses a charge‐transfer (CT) complex composed of racemic (rac)‐1,1′‐bi‐2‐naphthol, which acts as an electron donor, and 2,5‐substituted 1,4‐benzoquinone, which acts as an electron acceptor. This CT host system can selectively include aromatic guest molecules into a channel‐like cavity by tuning the packing of the electron‐donor and electron‐acceptor molecules. Characteristically, the color and diffuse reflectance spectra (DRS) of the inclusion CT complex can be tuned by changing the type of the component 2,5‐substituted 1,4‐benzoquinone. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
Picture‐IAT versus Word‐IAT: level of stimulus representation influences on the IAT
Authors: Foroni Francesco , Bel‐Bahar Tarik
Published: April 2009

The Implicit Association Test is a paradigm designed to assess individual differences in implicit cognition. The goal of this report was to examine the reasons for discrepant effect magnitudes obtained with two presumably interchangeable versions: Picture‐IAT (P‐IAT) and Word‐IAT (W‐IAT). We show that this discrepancy is due to the relation between stimuli and referent category: the level of representation (LR) at which a stimulus represents an intended category. Experiment 1 replicates the discrepancies found in previous research. Experiments 2–4 show that increasing the LR of stimuli increases the IAT effect. LR affects the magnitude of the IAT effect even when modality and other features of the stimuli are kept constant. The utility of LR for future investigations examining the IAT paradigm is discussed. Copyright © 2009 John Wiley & Sons, Ltd.
Anaplastic large cell lymphoma: one or more entities among T‐cell lymphoma?
Authors: Fornari Alessandro , Piva Roberto , Chiarle Roberto , Novero Domenico , Inghirami Giorgio
Published: April 2009

Anaplastic large cell lymphoma (ALCL) is a subtype of peripheral T‐cell lymphoma (PTCL) first described in 1985 as a lymphoid malignancy characterized by marked cellular pleomorphism, propensity to grow cohesively, tendency to invade lymph node sinuses and diffuse expression of CD30 1. The discovery of the t(2;5), involving the anaplastic lymphoma kinase (ALK) gene on chromosome 2 and the nucleophosmin (NPM) gene on chromosome 5 in the majority of systemic ALCL, has soon pointed out that ALCL is a clinically and biologically heterogeneous disease. While ALK‐positive (ALK+) ALCL is usually characterized by onset in children and young adults and better prognosis, epidemiology, poor outcome and possibly genetic defects of ALK‐negative (ALK−) ALCL suggest that this neoplasms should be considered an independent pathological entity. The aim of this review is to illustrate clinical features, histology, immunophenotype, genetics and biology of ALCL and discuss possible relationship(s) among different T‐non‐Hodgkin lymphoma (T‐NHL). Copyright © 2009 John Wiley & Sons, Ltd.
Atomic force microscopy evidence for conformational changes of fibronectin adsorbed on unmodified and sulfonated polystyrene surfaces
Authors: Kowalczyńska Hanna M. , Kołos Robert , Nowak‐Wyrzykowska Małgorzata , Dobkowski Jacek , Elbaum Danek , Szczepankiewicz Andrzej , Kamiński Jarosław
Published: April 2009

The effect of polystyrene surface polarity on the conformation of adsorbed fibronectin (FN) has been studied with atomic force microscopy. We demonstrated that bare sulfonated and nonsulfonated polystyrene surfaces featured similar topographies. After the FN adsorption, direct comparison of both types of substrata revealed drastically different topographies, roughness values, and also cell‐adhesive properties. This was interpreted in terms of FN conformational changes induced by the surface polarity. At high‐solute FN concentrations the multilayer FN adsorption took place resulting, for the sulfonated substratum, in an increase of surface roughness, whereas for the nonsulfonated one the roughness was approximately stable. Conversely, the FN conformation characteristic for the first saturative layer tended to be conserved in the consecutive layers, as evidenced by height histograms. The height of individual FN molecules indicated, consonantly with the derived thickness of the adsorbed protein layer (the latter value being 1.4 nm and 0.6 nm, respectively, for an unmodified and sulfonated polystyrene surface), that molecules are flattened on polar surfaces and more compact on nonsulfonated ones. It was also demonstrated that the FN adsorption and conformation on polymeric substrata, and hence the resultant cell‐adhesive properties, depended on the chemistry of the original surface rather than on its topography. Our results also demonstrated the ability of surface polarity to influence the protein conformation and its associated biological activity. © 2009 Wiley Periodicals, Inc. J Biomed Mater Res, 2009
Regucalcin is under‐expressed in human breast and prostate cancers: Effect of sex steroid hormones
Authors: Maia Cláudio , Santos Cecília , Schmitt Fernando , Socorro Silvia
Published: April 2009

Regucalcin plays an important role in maintenance of intracellular Ca2+ homeostasis, suppresses cell proliferation, inhibits expression of oncogenes, and increases the expression of tumour suppressor genes. This suggests that regucalcin functions may be altered in cancer tissues. In this study the regucalcin expression in breast and prostate cancer cases was analysed by RT‐PCR and immunohistochemistry showing that the mRNA and/or protein are under‐expressed in these tumors. The effect of sex steroid hormones on regucalcin expression in breast and prostate cancer cells was determined by real‐time PCR. MCF‐7 and LNCaP cells were stimulated with 0, 1, and 10 nM of 17β‐estradiol (E2) or 5α‐dihydrotestosterone (DHT), respectively, for 0, 6, 12, 24, and 48 h. MCF‐7 cells were also stimulated with E2 conjugated to BSA (E2‐BSA). To explore the mechanisms underlying the sex steroid regulation of regucalcin expression, control treatments with ICI 182,780, flutamide and cyclohexamide were carried out. E2 effects regulating regucalcin expression were not abrogated in the presence of ICI 182,780, and were similar to those observed with E2‐BSA, which suggests the involvement of a membrane‐bound estrogen receptor. In LNCaP cells, DHT down‐regulated regucalcin expression, an effect inhibited by the presence of both flutamide and cyclohexamide, suggesting the involvement of androgen receptor and de novo protein synthesis. The loss of regucalcin expression in breast and prostate cancer cases and the regulation of its expression by sex steroid hormones suggest that it may be associated with development and progression of these human tumors. J. Cell. Biochem. 107: 667–676, 2009. © 2009 Wiley‐Liss, Inc.
The synthesis of possible hydroxylated metabolites of 2‐chlorophenothiazine derivatives
Authors: Zirnis Aija , Suzuki Joseph K. , Dickson Donald E. , Laitar Robert A. , Manian Albert A.
Published: April 2009

The synthesis of 7‐hydroxy, 8‐hydroxy and 7,8‐dihydroxy prochlorperazines (3a) and per‐phenazines (3b) is reported. The parent ehlorophenothiazines were prepared analogously to previously reported chlorpromazine (3e) metabolite syntheses. The prochlorperazine side chain was introduced in one step using 1‐(3‐chloropropyl)‐4‐methylpiperazine and the perphenazine side chain in two steps, first reaction with 1‐bromo‐3‐chloropropane followed by reaction with 1‐piperazineethanol. The methoxymethyleneoxy O‐proteetive groups were removed under mild conditions using methanolic hydrogen chloride. The preparations of 7‐hydroxydesmethylprochlorperazine and 7‐hydroxychlorpromazine quaternary methyl iodide are also reported.
Synthesis of ageratochromene dimer
Authors: Schwarz Meyer
Published: April 2009

Reflux of a benzene solution of 2,2‐dimethyl‐6,7‐dimethoxy‐4‐chromanol in the presence of a catalytic amount of p‐toluenesulfonic acid leads to ageratochromene dimer (II) rather than to ageratochromene (I). Treatment of I under the same conditions also produces II which is identical with the dimer of ageratochromene isolated by Kasturi and Manithomas from Ageratum conyzoides L.
Novel two step synthesis of pyrazoles and isoxazoles from aryl methyl ketones
Authors: Lin Yang‐i , Lang S. A.
Published: April 2009

Various acetyl aromatics when reacted with dimethylformamide dimethyl acetal gave 1‐aryl‐3‐dimethylamino‐2‐propen‐1‐ones. These intermediates are masked β‐ketoaldehydes and react with hydrazine hydrate or hydroxylamine at room temperature to give in good yields pyrazoles or isoxazoles.
Carbon‐13 and nitrogen‐15 nuclear magnetic resonance of physostigmine (eserine)
Authors: Stenberg Virgil I. , Narain Nand K. , Singh S. P. , Obenauf Ralph H. , Albright M. J.
Published: April 2009

The 15N and 13C nmr spectra of physostigmine are discussed along with complete assignment of the signals. This alkaloid 15 N nmr spectrum is notable because it contains nitrogens in three different environments.
as‐Triazino[4,5‐a]indoles. II. Etude des as‐triazinoindolones
Authors: Robba M. , Maume D. , Lancelot J. C.
Published: April 2009

Lasynthèsede dihydro‐1,2 oxo‐1 as‐triazino[4,5‐a]indoles est effectuée soit par réarrangement en milieu alcalin d'oxadiazolyl‐2 indoles, soit par cyclisation de N‐ethoxyméthylidènehydrazides indoliques. Le dihydro‐3,4 oxo‐4 as‐triazino[4,5‐a]indole est accessible par cyclisation de la N‐carbéthoxyhydrazone du formyl‐2 indole. La tautomérie lactime‐lactame est étudiée à l'aide des spectres ir et de rmn.
Synthesis of 2‐methyl‐3‐(3,5‐diallyl‐4‐hydroxyphenyl)‐4‐quinazolones as possible anticonvulsants
Authors: Rastogi V. K. , Parmar S. S. , Singh S. P. , Akers T. K.
Published: April 2009

A series of 2‐methyl‐3‐(3,5‐diallyl‐4‐hydroxyphenyl)‐4‐quinazolones were prepared as possible anticonvulsants. All compounds were evaluated for their anticonvulsant activity against pentylene‐tetrazol‐induced seizures and their ability to potentiate sodium pentobarbital sleeping time in albino mice.
Investigations into the cine‐Amination of 4‐Substituted‐5‐bromopyrimidines by potassium amide in liquid ammonia
Authors: Rasmussen C. A. H. , Van Der Plas H. C. , Grotenhuis P. , Koudijs A.
Published: April 2009

The cine‐amination of some 4‐R‐5‐bromopyrimidines (t‐butyl, phenyl, methoxyl, piperidine, methyl, methylamino, anilino, amino) by potassium amide in liquid ammonia has been studied. Evidence is presented that the conversion into the corresponding 4‐substituted‐6‐aminopyrimidines can proceed in part via an SN(ANRORC) mechanism, involving an open‐chain intermediate, provided that the substituent at C‐4 does not contain an acidic proton in the α‐position to the pyrimidine ring. 5‐Bromo‐4‐piperidinopyrimidine yields the tele‐amination product, 2‐amino‐4‐piperidinopyrimidine, alongside the 6‐amino derivative. It is proven that the tele‐amination does not proceed via an SN(ANRORC) mechanism.
Additions radicalaires. 16 Additions d'hétérocycles oxygénés aux allènes
Authors: Montaudon E. , Thepénier J. , Lalande R.
Published: April 2009

L'addition radicalaire du tétrahydrofuranne et du tétrahydropyranne à divers carbures alléniques conduit en particulier à des monoadduits. Une substitution croissante sur le système allénique entraǐne un enrichissement relatif en adduit issu de l'attaque centrale (pouvant alter de moins de 1% avec le propadiène á plus de 99% avec le diméthyl‐2,4 pentadiène‐2,3) et une diminution de la quantité de monoadduits isolés consécutive à une augmentation de la quantité de résidue formés.
Preparation and characterization of a new meso‐substituted tetrapyrrole macrocyclc: Meso‐tetra[2‐(3‐carboxyethyl)furyl]porphine, [TFP]
Authors: Momenteau Michel , Loock Bernard , Bisagni Emile
Published: April 2009

The preparation of meso‐substituted tetrafuryl‐porphines is described. These new compounds are very soluble either in organic solvent or in water depending upon the furyl groups substitution. Their spectroscopic absorption, nmr characteristics, and some of their electrochemical properties are reported.