bluuebunny/crossref_metadata_2025 huggingface dataset:
Reproductive Injustice and the Politics of Trans Future in France
Authors: Fiorilli Olivia
Published: November 2019

This article tackles the issue of trans futures through a critical discussion of trans reproductive injustice in France. Most notably, it focuses on one of its many facets: the cisnormative administration of publicly funded gamete cryo-preservation. For a long time trans people in France have been excluded from the possibility of banking their gametes. Only recently the situation is starting to change, but the right of all trans people to cryo-preserve their gametes is far from being fully recognized. The first part of the article traces the genealogy of the exclusion of trans people from gamete cryo-preservation by offering some historical background of the necropolitical governance of trans reproduction in France. The second part explores in detail a public controversy over trans gamete cryo-preservation that emerged in 2013. Through a close reading of this controversy, the article tackles the discursive and material underpinnings of this cisnormative regulation of gamete cryo-preservation.
“I Sexually Identify as an Attack Helicopter”
Authors: Shalloe Harper
Published: November 2019

This article jumps off and theorizes out from the viral meme “I Sexually Identify as an Attack Helicopter” to think trans as a cut across diagrams of control and counterinsurgency. Terming the set of digital and discursive technologies for capturing the threat of trans potentiality the “biopolitics of identification,” it traces spectral appearances of trans as a contrivance for violence through lived and imagined scenes of surveillance and security.
The Mortality and Medical Costs of Air Pollution: Evidence from Changes in Wind Direction
Authors: Deryugina Tatyana , Heutel Garth , Miller Nolan H. , Molitor David , Reif Julian
Published: November 2019

We estimate the causal effects of acute fine particulate matter exposure on mortality, health care use, and medical costs among the US elderly using Medicare data. We instrument for air pollution using changes in local wind direction and develop a new approach that uses machine learning to estimate the life-years lost due to pollution exposure. Finally, we characterize treatment effect heterogeneity using both life expectancy and generic machine learning inference. Both approaches find that mortality effects are concentrated in about 25 percent of the elderly population. (JEL I12, J14, Q51, Q53)
Predicting and Understanding Initial Play
Authors: Fudenberg Drew , Liang Annie
Published: November 2019

We use machine learning to uncover regularities in the initial play of matrix games. We first train a prediction algorithm on data from past experiments. Examining the games where our algorithm predicts correctly, but existing economic models don’t, leads us to add a parameter to the best performing model that improves predictive accuracy. We then observe play in a collection of new “ algorithmically generated” games, and learn that we can obtain even better predictions with a hybrid model that uses a decision tree to decide game-by-game which of two economic models to use for prediction. (JEL C70, C91)
Frequencies of gastrointestinal parasites among students of primary school in Al Kalakla Locality, Khartoum State, Sudan: a cross-sectional study
Authors: Abdalazim Hassan Hala , Abd Alla Ahmed Bakheet , Elfaki Tayseer Elamin Mohamed , Saad Mohammed Baha Eldin Ahmed
Published: November 2019

Background:Intestinal parasite spread in tropical countries is especially common among primary school students. This study aimed to determine the frequencies of the intestinal parasite in Alkalakla locality, Khartoum state.

Methods:This study was conducted in school students in Al-kalakla locality in Khartoum state from period between 20th December 2016 to 5th May 2017. Stool samples were collected from 134 randomly selected students, of whom 67 were males and 67 were females.  All samples were examined using the wet preparation technique, formal ether concentration technique and saturated sugar floatation technique.

Results:The frequency of intestinal parasites was 35.5% overall in the students examined; females were more affected than males (38.8% and 32.8%, respectively). The more affected age groups were 12-14 years followed by 9-11 and 6-8 years old (53.8%, 36.3% and 26.4% respectively). The least frequent intestinal parasite wasTaeniaspp. (1.5%) followed byGiardia lamblia(3.7%),Schistosoma mansoniandAscaris lumbricoides(5.2% each),Entamoeba coli(7.5%),Hymenolepis nana(10.4%), andEntamoeba histolytica(16.4%). In total, 20.9% were infected with single parasite while 14.9% were infected with more than one parasite. The frequency of parasite by formal ether concentration method was 35.8 %, by wet preparation method was 17.9 % and by the saturated sugar flotation method was 16.4%.

Conclusion:Our data showed that intestinal parasites were common in school students; however, females were more affected than males and the 12-14-years age group was the most affected age group.  The formal ether concentration method was the best method for detecting of intestinal parasite.
Relationship and career challenges faced by people infected with HIV in Malaysia
Authors: Tuan Abdullah Tuan Norbalkish , Mat Min Ruhani , Hossain Mosharaf , Abdullah Siti Salina
Published: November 2019

Background: This study was completed at two general hospitals in Malaysia that provide treatment for HIV patients. The aim of the study was to explore the experiences of people infected with HIV (PIWH) and how they cope with HIV.

Methods: This qualitative study was based on a social constructivist and grounded theory approach. A total of 12 PIWH were selected by purposive sampling, all of whom participated in semi-structured and audio-recorded interviews, which were supported with non-participant observations and diary entries on three occasions for each participant. The interviews and diaries were transcribed and analysed using the grounded theory approach, which was assisted by utilizing NVIVO-8 to identify the themes related to the experiences of the participants.

Results: PIWH experienced challenges related to their career and relationships with family and others. These challenges led to difficulties in gaining employment and career development, as well as feelings of denial, being uncomfortable, rejection, and labelling. They found that their lives were totally and dramatically changed after being tested positive for HIV.

Conclusions: Among PIWH, HIV impacted relationships with significant others and career development. The absence of support and acceptance from significant others affected the ability of PIWH to cope with their daily challenges. The results of this study have implications for policymakers in terms of gaining sufficient knowledge and awareness to provide prevention programmes for HIV/AIDS.
ОСОБЕННОСТИ МОДЕЛИРОВАНИЯ ЛОГИСТИЧЕСКИХ СИСТЕМ
Authors: Shakirov Arslan Ainurovich , Zaripova Rimma Soltanovna
Published: November 2019

Целью данной статьи является изучение того, насколько важно учитывать неопределенность в проблеме моделирования логистической системы на этапе планирования. Рассмотрены структурные различия между решением, основанным на неопределенном спросе, и решением, основанным на детерминированном спросе. Некоторые из этих различий помогают хеджировать неопределенность, не увеличивая при этом стоимость эксплуатации графика.
Technical analysis and trading in the financial market
Authors: Михайлов Алексей , Mihaylov Aleksey
Published: November 2019

The manual is designed to organize independent work with the Thomson Reuters system of students studying the discipline "Technical analysis and trading in the financial market using Bloomberg and other systems". Theoretical and practical information is given, as well as an algorithm for working with the Thomson Reuters system to solve educational and scientific problems is proposed.
Meets the requirements of the Federal state educational standards of higher education of the last generation.
It is intended for students studying in the direction of preparation 38.04.01 "Economics", master's program "Securities and financial engineering".
Mental health of Warsaw middle school students. Mokotow Study 2004–2016
Authors: Bobrowski Krzysztof , Ostaszewski Krzysztof , Pisarska Agnieszka
Published: November 2019

Cel pracy

Celem było oszacowanie rozpowszechnienia zaburzeń zdrowia psychicznego w części populacji młodzieży ..................................oraz określenie trendów w latach 2004 – 2016.

Metoda

Powtarzane co cztery lata badania przekrojowe obejmowały uczniów trzecich klas gimnazjalnych, ............................... Stosowano losowy dobór klas do próby z poprawką na dobór klastrowy. Audytoryjne badania ankietowe prowadzono w trakcie lekcji szkolnych. Wskaźniki opisywały problemy: 1/ internalizacyjne (symptomy depresji wg skróconej skali CES-D oraz inne zaburzenia emocjonalne, wg subiektywnej oceny badanych); 2/ eksternalizacyjne – współwystępowanie dwóch spośród trzech typów zachowań (nadużywanie substancji psychoaktywnych, sprawstwo przemocy, wykroczenia); 3/ mieszane.

Wyniki

W 2016 roku 42% młodzieży przejawiało symptomy zaburzeń zdrowia psychicznego. Problemy te częściej dotykały dziewcząt (48%) niż chłopców (36%). W latach 2008 – 2016 istotnie wzrósł odsetek młodzieży z problemami internalizacyjnymi. Przyczynił się do tego wzrost rozpowszechnienia symptomów depresji. Jednocześnie odnotowano znaczący spadek odsetka młodzieży z problemami eksternalizacyjnymi. Było to pochodną ograniczenia nadużywania substancji psychoaktywnych oraz ograniczenia sprawstwa przemocy.

Wnioski

Narastanie problemów internalizacyjnych, ryzyka depresji wśród nastolatków oraz rozpowszechnienia innych problemów emocjonalnych, sugeruje pilną potrzebę opracowania lub adaptacji skutecznych programów profilaktycznych oraz poszerzenia dostępności oferty pomocy psychologicznej i psychiatrycznej dla młodzieży.
Parodontoprotective action of oral applications of soy isoflavons in rats after orthodontic operation on the background of experimental diabetes mellitus
Authors: Azari Mohammed Ali Mehrdad , Morozov A. L.
Published: November 2019

Background.  To determine the periodontoprotective effect of soy isoflavones in rats after orthodontic surgery on the background of diabetes mellitus.Methods. In rats, type 1 diabetes was reproduced with aloxane (intraperitoneally at a dose of 100 mg / kg once). From day 12, rats were fitted with orthodontic springs. One of these groups of rats received oral gel applications with soy isoflavones from the first day of the experiment at a dose of 0.5 ml daily for 34 days. The activity of elastase, catalase, urease, lysozyme and the content of malondialdehyde (MDA) were determined in the gum. In the alveolar process of the lower jaw, the activity of alkaline (alkaline phosphatase) and acid (APH) phosphatases, the content of calcium and protein were determined. The antioxidant-prooxidant index (API) was calculated by the ratio of catalase activity and MDA content, the degree of dysbiosis was calculated by the ratio of the relative activities of urease and lysozyme, the mineralizing index (MI) was calculated by the ratio of alkaline phosphatase and APH activity, and the degree of mineralization (DM) was calculated by the ratio of calcium and protein.Results. In rats with diabetes mellitus, the level of elastase, MDA, urease and the degree of dysbiosis increased with a decrease in the API index and lysozyme activity. Orthodontic surgery showed a certain tendency to normalize these parameters, while the application of a gel containing soy isoflavones completely normalized all indicators. In the bone tissue of periodontium in rats with diabetes mellitus, the activity of alkaline phosphatase and MI decreased, but the activity of APH increased. Orthodontic surgery significantly increased the activity of alkaline phosphatase, slightly changing the activity of APH and the index of API. Application of the gel with isoflavones completely normalized the activity of phosphatases, MI and significantly increased the degree of mineralization of bone tissue.Conclusion. Rats with type 1 diabetes develop periodontitis. Orthodontic surgery does not exacerbate the pathological condition, showing even a slight tendency to normalize. Oral applications of a gel containing soy isoflavones have a periodontoprotective effect, normalizing all biochemical parameters of the gums and bone periodontal tissue.
‘Social justice for all!’ The relative silence of social work in abortion rights advocacy
Authors: Beddoe Elizabeth , Hayes Trish , Steele Jessica
Published: November 2019

Social work has been largely silent on matters of reproductive rights, particularly in relation to abortion. This may partially be explained by abortion being secured as a part of health care in many countries. However, elsewhere, abortion remains in criminal codes with service access controlled via medico-legal barriers. We make a case for the increased visibility of reproductive justice within education and professional activity, employing case studies from Australia, the Republic of Ireland and New Zealand to illustrate recent social work advocacy on abortion rights. Social work abortion activists report two themes: professional bodies have varied their approach to advocacy for abortion rights due to political sensitivities; and social work involvement in campaigns has reflected individual and grass-roots advocacy. Improved education about reproductive justice for social workers, alongside greater collective professional advocacy, are needed to contribute to campaigns together with women’s and human rights groups, as well as public health champions.
2019 Topical Meeting on Optical Interference Coatings: Manufacturing Problem Contest [invited]
Authors: Poitras Daniel , Li Li , Jacobson Michael R. , Cooksey Catherine C.
Published: November 2019

For the seventh Manufacturing Problem Contest, participants were
challenged to fabricate an optical filter with transmittance specified
for

s

-polarization at two incident angles:
10° and 50° from 400 nm to 1100 nm. The problem required that
contestants be equally versed in the design, deposition, and
measurement of optical filters in order to achieve good results. Eight
teams from five different countries participated in the contest using
various deposition techniques. The fabricated filters had a total
thickness between 8.2 µm and 17.6 µm and a total number of layers from
74 to 255, which were deposited onto one or both sides of the
substrate. The performances of the filters were measured by two
independent laboratories. The evaluation results were presented at the
Topical Meeting on Optical Interference Coatings conference held in
Santa Ana Pueblo, New Mexico, in June 2019.
Eventless news: Blindspots in journalism and the 'long tail' of news content
Authors: Sjøvaag Helle , Kvalheim Nina
Published: November 2019

The news media is frequently criticized for ignoring, missing or overseeing important, socio-politically relevant news. Such journalistic blindspots are often part of the 'long' news agenda, requiring resources, in-depth knowledge and investigation. In this article, we analyse what
news topics are most infrequently covered by the media ‐ the micro-categories of content analysis. A content analysis of 70 news outlets in Norway (n=8182) reveals that the news topics receiving less than 1 per cent of coverage are social issues, international crime and the economy.
This bottom-up perspective demonstrates that under-reported news constitutes predominantly 'eventless' issues, sustaining event-centredness as an agenda-setting news value. Finding that more than half of the content categories in the Norwegian corpus receive less than 1 per cent coverage,
we propose, however, that the sum of these blindspots engenders a 'long tail' of journalistic coverage that together facilitates news diversity.
Social news: Connecting virtuality with reality in cyberspace
Authors: Wu Yanfang
Published: November 2019

This study seeks to understand how American journalists integrate social media in news production by conducting semi-structured qualitative interviews. Thirteen journalists and editors from thirteen newsrooms of variety size, and multiple platforms (newspaper, radio, television, magazine
to online-only news organizations) were interviewed. Based on the media richness theory, the study shed light on how journalists delve into the virtual world, build connections between virtuality and reality through finding sources, interacting with audiences, constructing communities in the
virtuality and integrating virtuality with reality into the news production process. With its rich multimedia features that allow immediate interaction between journalists and audiences, social media has become a rich medium that connects virtuality to reality in social news and, in particular,
immersive journalism.
Recognizing voice and redistributing power: Community theatre with refugees and asylum seekers in Leeds
Authors: Berelson Keziah , Cook Tamsin
Published: November 2019

This article analyses the experience of creating Women of Power (2018) with a diverse group of refugees and asylum seekers in Leeds. Using the normative framework of a dialogic continuum of micro and macro dramaturgies to guide the analysis, the risks and tensions present in several forms of theatre facilitation are considered. The article examines the complexities of critical reflection and language in relation to creating theatre and draws on Nancy Fraser's analysis of social injustice to consider the position of the facilitator when working with migrant populations. The article contends that an effective way to create an engaging aesthetic and to work as 'redistributors' of privilege may be to offer sustainable, dramatic and pragmatic structures for participants to add their voices to.
The Foreigner – Unknown Unlabelled Unexpected
Authors: Viora Angela
Published: November 2019

The open-ended durational performance The Foreigner is a personal response to the migration question currently involving Europe, Africa and the Middle East. The work explores and questions notions of identity and territoriality, reality and virtuality, through the anonymity and vulnerability of the artist, and the active participation of the audience in the performance process. The artist's body worked as a mirror that reflected personal ideas, constructs, and emotions of the visitors, who experience and interpret the image of The Foreigner according to their personal histories and past experiences. The result is a multiplicity of perspectives on migration and beyond.
STUDI TENTANG JENIS KRUSTASEA YANG HIDUP DI KARANG BATU DAN PERANANNYA DALAM EKOSISTEM TERUMBU KARANG
Authors: Pratiwi Rianta
Published: November 2019

STUDIES ON CRUSTACEANS SPECIES LIVING IN THE CORAL REEF AND THEIR ROLE IN ECOSYSTEM. Crustaceans are one of the most specis invertebrates in coral reefs, comprising approximately 20 % of all invertebrate species. This taxa often found clearly living in coral communities. The order Decapoda is the most common crustaceans observed the coral reefs due to their relatively large size and having bright colours. In addition, decapods contribute in the environmental balance and having important roles in coral reef ecosystem such as defending live coral from predators and helping growth of corals.
ESTUDANTES BEM-SUCEDIDOS NO EXAME NACIONAL DO ENSINO MÉDIO
Authors: Wanderer Fernanda , Dal Moro Marília Bervian
Published: November 2019

O artigo tem o propósito de discutir como são constituídos, em mídias sociais do Facebook, os estudantes bem-sucedidos no Exame Nacional do Ensino Médio (Enem). Os aportes teóricos utilizados advêm da matriz foucaultiana, principalmente os conceitos de governamentalidade, discurso e processos de objetivação e subjetivação. O material empírico é composto por mais de 100 postagens reunidas entre 2015 e 2018, oriundas de páginas do Facebook endereçadas aos candidatos que se preparam para o Enem. O resultado analítico mostrou que nas enunciações examinadas é possível perceber um forte incentivo à participação no Enem. Além disso, os candidatos tornam-se empreendedores de seu próprio desempenho nas provas, constituindo modos específicos de ser um bom estudante, o qual precisa, basicamente, de muito estudo e dedicação. Neste sentido, pode-se dizer que muito mais do que servir como uma forma de ingresso no Ensino Superior, o Exame atua como um dos mecanismos que constitui subjetividades alinhadas à racionalidade neoliberal presente em nossa sociedade.
Teens' Perspectives on Barriers and Facilitators to Accessing School-based Clinics
Authors: Charette Catherine , Metge Colleen , Struthers Ashley , Enns Jennifer E. , Nickel Nathan C. , Chartier Mariette , Chateau Dan , Burland Elaine , Katz Alan , Brownell Marni
Published: November 2019

Objective: This qualitative study explores teens' perspectives on facilitators and barriers to accessing school-based clinics, emphasizing the importance of youth self-report. Methods: We conducted in-person interviews with teens (N = 25) at 2 high schools that had school-based
clinics in Winnipeg, Manitoba (Canada). We supplemented the interviews with a brief questionnaire administered to a sample of teens at both schools (N = 105). Data were iteratively coded and analyzed using NVivo. Results: Teens framed 5 clinic attributes that facilitated access: confidential,
welcoming, judgment-free, validating and understanding, and fast/easy/convenient. Teens identified judgment from peers, fear and anxiety, hours/wait times, lack of privacy, and teens who gather at the clinic to socialize as factors that made the clinic hard to access or inhibited access entirely.
Conclusions: School-based clinics were highly regarded by teens who used them. The most important factors underlying ease of use were assurance of confidentiality and a positive client-provider relationship that made teens feel safe and comfortable. However, considerable individual
and structural barriers remain to ensuring the clinics are teen-friendly and accessible.
Boundary Regularity for p-Harmonic Functions and Solutions of Obstacle Problems on Unbounded Sets in Metric Spaces
Authors: Björn Anders , Hansevi Daniel
Published: November 2019

The theory of boundary regularity for p-harmonic functions is extended to unbounded open sets in complete metric spaces with a doubling measure supporting a p-Poincaré inequality, 1 < p < ∞. The barrier classification of regular boundary points is established, and it is shown that regularity is a local property of the boundary. We also obtain boundary regularity results for solutions of the obstacle problem on open sets, and characterize regularity further in several other ways.
Complex interpolation of the predual of Morrey spaces over measure spaces
Authors: Burenkov Victor I. , Hakim Denny I. , Nakai Eiichi , Sawano Yoshihiro , Sobukawa Takuya , Tararykova Tamara V.
Published: November 2019

We prove that block spaces
defined on

ℝ
n

{\mathbb{R}^{n}}

with an arbitrary Radon measure, which are known to be the preduals of Morrey spaces,
are closed under the first and the second complex interpolation method.
The proof of our main theorem uses the duality theorem in the complex interpolation method,
the complex interpolation of certain closed subspaces of Morrey spaces, a characterization of the preduals of block spaces, and
some formulas related to the Calderón product.
A version of Hake’s theorem for Kurzweil–Henstock integral in terms of variational measure
Authors: Skvortsov Valentin , Tulone Francesco
Published: November 2019

We introduce the notion of variational measure with respect to a derivation basis in a topological measure space and consider a Kurzweil–Henstock-type integral related to this basis. We prove a version of Hake’s theorem in terms of a variational measure.
Ageing of Zirconia Dedicated to Dental Prostheses for Bruxers Part 2: Influence of Heat Treatment for Surface Morphology, Phase Composition and Mechanical Properties
Authors: Nakonieczny Damian S. , Sambok Agata , Antonowicz Magdalena , Basiaga Marcin , Paszenda Zbigniew K. , Krawczyk Cezary , Ziębowicz Bogusław , Lemcke Hubert , Kałużyński Piotr
Published: November 2019

Purpose: This part of the study focuses on the influence of zirconia heat treatment for surface morphology, phase composition and mechanical properties

Methods: Zirconia samples was prepared with ISO 13356:2013 and ISO 14704:2008 recommendations. X-ray diffraction, observations (SEM) and (AFM), microhardness (Olivera & Phara method), and static bending test (4PBT) were taken.

Results: characterization of YSZ and high temperature heat treatment has clearly shown that the aging process influences the change in phase composition of the material, significantly worsening the topography. In turn, re-treatment of the high temperature made after the artificial aging process results in reverse transformation of the desired tetragonal phase, but does not affect the improvement of surface morphology.

Conclusions: The research made it possible to assess the negative impact of the zirconium oxide aging simulation process. Because of the failure to achieve the intended results, it was also proved that the high-temperature re-processing was not appropriate.
SaltWalks: Vancouver, Nanaimo, Toronto
Authors: Cutler Randy Lee
Published: November 2019

SaltWalks (2013-ongoing) is a performance series that takes participants on site-specific salt tasting walks through different city neighborhoods. Each walk begins at a designated meeting point where fellow walkers sample five different salts, including table salt, Celtic sea salt, Himalayan rock salt, Hawaiian clay salt, and Alderwood smoked salt. These tastings are served from a custom salt apron designed specifically for walking. Our savory comparisons initiate far-ranging conversations exploring the uses of salt across time and different cultures. Through an engagement with this elemental mineral, these walks become a pedagogical platform that embodies aesthetic and philosophical enquiries into the importance of this substance to ritual, survival, health, industry and the imagination.
Charge-Balanced Electrical Stimulation Can Modulate Neural Precursor Cell Migration in the Presence of Endogenous Electric Fields in Mouse Brains
Authors: Iwasa Stephanie N. , Rashidi Abdolazim , Sefton Elana , Liu Nancy X. , Popovic Milos R. , Morshead Cindi M.
Published: November 2019

Electric fields (EFs) can direct cell migration and are crucial during development and tissue repair. We previously reported neural precursor cells (NPCs) are electrosensitive cells that can undergo rapid and directed migration towards the cathode using charge-balanced electrical stimulationin vitro. Here, we investigate the ability of electrical stimulation to direct neural precursor migration in mouse brainsin vivo. To visualize migration, fluorescent adult murine neural precursors were transplanted onto the corpus callosum of adult male mice and intracortical platinum wire electrodes were implanted medial (cathode) and lateral (anode) to the injection site. We applied a charge-balanced biphasic monopolar stimulation waveform for three sessions per day, for 3 or 6 d. Irrespective of stimulation, the transplanted neural precursors had a propensity to migrate laterally along the corpus callosum, and applied stimulation affected that migration. Further investigation revealed an endogenous EF along the corpus callosum that correlated with the lateral migration, suggesting that the applied EF would need to overcome endogenous cues. There was no difference in transplanted cell differentiation and proliferation, or inflammatory cell numbers near the electrode leads and injection site comparing stimulated and implanted non-stimulated brains. Our results support that endogenous and applied EFs are important considerations for designing cell therapies for tissue repairin vivo.
Congenital hypogonadotropic hypogonadism/Kallmann syndrome is associated with statural gain in both men and women: a monocentric study
Authors: Maione Luigi , Pala Giovanna , Bouvattier Claire , Trabado Séverine , Papadakis Georgios , Chanson Philippe , Bouligand Jérôme , Pitteloud Nelly , Dwyer Andrew A , Maghnie Mohamad , Young Jacques
Published: November 2019

Context

Congenital hypogonadotropic hypogonadism/Kallmann syndrome (CHH/KS) is a rare condition characterized by gonadotropin deficiency and pubertal failure. Adult height (AH) in patients with CHH/KS has not been well studied.

Objective

To assess AH in a large cohort of patients with CHH/KS.

Patients

A total of 219 patients (165 males, 54 females). Parents and siblings were included.

Methods

AH was assessed in patients and family members. AH was compared to the general French population, mid parental target height (TH) and between patients and same-sex siblings. Delta height (∆H) was considered as the difference between AH and parental TH. ∆H was compared between patients and siblings, normosmic CHH and KS (CHH with anosmia/hyposmia), and according to underlying genetic defect. We examined the correlations between ∆H and age at diagnosis and therapeutically induced individual statural gain.

Results

Mean AH in men and women with CHH/KS was greater than that in the French general population. Patients of both sexes had AH > TH. Males with CHH/KS were significantly, albeit moderately, taller than their brothers. ∆H was higher in CHH/KS compared to unaffected siblings (+6.2 ± 7.2 cm vs +3.4 ± 5.2 cm, P < 0.0001). ∆H was positively correlated with age at diagnosis. Neither olfactory function (normosmic CHH vs KS) nor specific genetic cause impacted ∆H. Individual growth during replacement therapy inversely correlated with the age at initiation of hormonal treatment (P < 0.0001).

Conclusions

CHH/KS is associated with higher AH compared to the general population and mid-parental TH. Greater height in CHH/KS than siblings indicates that those differences are in part independent of an intergenerational effect.
A Genetic Screen for Genes That Impact Peroxisomes in Drosophila Identifies Candidate Genes for Human Disease
Authors: Graves Hillary K , Jangam Sharayu , Tan Kai Li , Pignata Antonella , Seto Elaine S , Yamamoto Shinya , Wangler Michael F
Published: November 2019

Peroxisomes are subcellular organelles that are essential for proper function of eukaryotic cells. In addition to being the sites of a variety of oxidative reactions, they are crucial regulators of lipid metabolism. Peroxisome loss or dysfunction leads to multi-system diseases in humans that strongly affect the nervous system. In order to identify previously unidentified genes and mechanisms that impact peroxisomes, we conducted a genetic screen on a collection of lethal mutations on the X chromosome in Drosophila. Using the number, size and morphology of GFP tagged peroxisomes as a readout, we screened for mutations that altered peroxisomes based on clonal analysis and confocal microscopy. From this screen, we identified eighteen genes that cause increases in peroxisome number or altered morphology when mutated. We examined the human homologs of these genes and found that they are involved in a diverse array of cellular processes. Interestingly, the human homologs from the X-chromosome collection are under selective constraint in human populations and are good candidate genes particularly for dominant genetic disease. This in vivo screening approach for peroxisome defects allows identification of novel genes that impact peroxisomes in vivo in a multicellular organism and is a valuable platform to discover genes potentially involved in dominant disease that could affect peroxisomes.
State Administration Reform Strategy in the Sphere of Civil Protection in the Context of European Integration of Ukraine
Authors: Бойко О. А.
Published: November 2019

The issues of public administration reforming in the sphere of civil protection in the context of European integration of Ukraine and with account for the current state of natural environment and technogeneous situation in Ukraine have been researched in the article.The need for reforming the State Emergency Service system is also driven by changes occurring in the state in the view of decentralization of the power, reform of state security and defense system, transfer of separate powers related to organization and provision of firefighting capabilities and emergency response from the state bodies to the local self-government bodies, etc.The state of Strategy for Reforming the State Emergency Service of Ukraine implementation, which aims at reforming the State Emergency Service of Ukraine system by 2020 and enhancing its ability to ensure fulfilment, in cooperation with other units of security and defense sector, of national security threats countermeasures in the sphere of civil protection has been analysed. The results of analysis of legislative instruments of strategic nature have been presented, adoption of which was important for further development of the unified state system of civil protection. Conceptual contradictions have been discovered, resolution of which requires development of a new legislation or amendments to the current legislation, including the Code of Civil Protection of Ukraine.The issue of introduction of the technogeneous and fire safety management system, based on risk-based approach and European standards, has been highlighted; some areas of this work have been reviewed.The first attempt of scientific analysis and search for the ways of implementation of the recently adopted Action Program of the Cabinet of Ministers of Ukraine and Sustainable Development Goals of Ukraine by 2030, aimed in particular at the further improvement of civil protection issues, has been made.The relevance of issues of public administration reforming in the sphere of civil protection under existing conditions and the role and the place of authorities at different levels in the reform tasks implementation have been clarified.
Promoting E-development of communities in Ukraine: conceptual and legal foundations (regarding the municipal data-driven governance)
Authors: Семчик О. О. , Приходько Х. В. , Сидоренко П. О. , Петрухін Ф. В.
Published: November 2019

The feasibility of scientific and legislative support for promoting e-development of communities and managing their resources based on data and ICT has been substantiated using a multidisciplinary approach. The article makes the case for introducing the concept of e-development of communities and using it in the suggested narrow and broad meaning; its components are defined. The purpose of such development is to strengthen the decentralization and to achieve the balance between social, economic and ecological indicators of development of communities in Ukraine. E-development is a system-forming category for existing concepts, methodologies, digital and next-generation capabilities to use data in all life areas of communities to identify and achieve key development goals. Key factors that hinder the implementation of data-driven governance and best practices of data governance for local self-governance have been identified. Promising directions for the implementation of the data-driven governance principle as well as the expected results from the increase in the efficiency of evaluation and analysis of such data are outlined. In the context of the application of the principle of data-driven governance, the importance and tasks of monitoring and evaluating e-development of communities have been described, including the development of laws and regulations, introduction of necessary organizational and administrative mechanisms, conducting awareness-raising activities, promotion of data and its social importance with regard to addressing local issues, etc. The article also focuses on the development of human capital for the data-driven governance, namely the importance of applying a professional approach to data governance is underlined incl. the introduction of the role of CDO at the level of both the centralized platform and data administrators - i.e. local self-governance bodies.
Analysis of the situation and trends in foreign trade of Dnipropetrovsk region: challenges and opportunities for the sustainable regional growth
Authors: Матвеєва О. Ю. , Шевченко Л. Г.
Published: November 2019

The article assesses the situation and analyzes the current trends in the development of domestic foreign trade through the case of Dnipropetrovsk region. The analysis is conducted through the lens of identifying challenges and opportunities for the region that are opened up by foreign trade. The impact of the region's foreign trade on its international economic relations in the context of Ukraine's European integration and the deployment of globalization processes is significant. Dnipropetrovsk region is one of the leading exporters and, according to the results of 2018, ranks second place among the regions of Ukraine by the export of goods. Therefore, choosing the region for the study is determined by the importance of the development of international trade in its territories to strengthen the position of Ukraine's international competitiveness. The article identifies and analyzes the indicators of foreign trade of the Dnepropetrovsk region with the world countries, as well as the economic result and effect of it’s influence. The focus is put on assessing and analyzing the dynamics of changes in the structure of export and import of goods. In particular, the tendency of decrease in export of services of Dnepropetrovsk region to the EU countries during 2014-2017 is analyzed as a negative trend. Positive trend visualizes through increasing of this indicator in 2018. Overall, the increase of the number of regional enterprises engaged in the foreign trade of goods was shown. Emphasis is placed on the commodity structure of export. It is composed of ferrous metals (46.3%) and ores, slag and ash (23.2%). The basis of the commodity structure of import is mineral fuels; oil and its distillation products (30.3%), machinery, equipment and mechanisms; electrical equipment (14.4%), chemical products and related industries (11.3%), and precious metals (11%). The dynamics of the change in the export structure indicates a certain slowdown in the process of transition to a ‘new type economy’, which should be based not on direct consumption of resources, but on innovation, knowledge and technology, their application in products and services production. The article is a summary of the situation in the field of foreign trade of the region, which is carried out in the framework of the task of drafting the Strategy of development of Dnipropetrovsk region for the period until 2027.
COMPOSICIÓN CORPORAL, PERFIL LIPÍDICO Y APTITUD FÍSICA EN MUJERES ADOLESCENTES EN MÉXICO
Authors: Hernández-Murúa José Aldo , Llamas-Hernández Baldomero , Salazar C Ciria Margarita , Gómez-Figueroa Julio Alejandro , Acuña-Cordova Cesar Augusto , De Paz-Fernández Jose Antonio
Published: November 2019

El objetivo de esta investigación fue determinar la composición corporal, el perfil de lípidos sanguíneos y aptitud física en mujeres adolescentes con y sin sobrepeso, y correlacionar cada variable con las demás. Se consideró un diseño transversal. Participaron 38 mujeres adolescentes con edades entre 14 y 19 años. Clasificadas como normopeso (n = 21) o sobrepeso (n = 17) según la gráfica de la Organización Mundial de la Salud mediante el IMC (kg/m²) en función del puntaje z para edades de 5 a 19 años (puntaje z: 0 a +1 DE = normopeso, +1 a +2 DE = sobrepeso). Se realizaron mediciones de composición corporal, perfil de lípidos sanguíneos (colesterol total, triglicéridos, cHDL, cLDL) y aptitud física (VO2pico y 1RM). Los resultados muestran que las adolescentes con normopeso fueron significativamente (p < 0.05) más bajas (M ± DE) en todas las variables de composición corporal que las mujeres adolescentes con sobrepeso. No se encontraron diferencias significativas en el VO2pico, 1RM ni en el perfil de lípidos sanguíneos. En conclusión, las mujeres adolescentes con sobrepeso presentan mayores niveles de composición y grasa corporal pero estos niveles superiores no parecen afectar los niveles de lípidos sanguíneos. Se encontró una asociación entre los niveles de aptitud física (VO2pico) y la composición corporal (% grasa, pliegues cutáneos). Se sugieren otros estudios para buscar la asociación entre los niveles de VO2pico y grasa corporal.
Adaptación del modelo de planificación ATR al entorno formativo. Aplicación en clases de taekwondo
Authors: Carazo-Vargas Pedro
Published: November 2019

La planificación ATR es un método de organización del entrenamiento deportivo que se aplica en busca de conseguir la óptima forma competitiva en atletas de distintas disciplinas. La presente disertación expone las principales características de este modelo de planificación y describe una posible manera de aplicarlo en el entorno educativo y de formación base. Se ejemplifica el empleo de dicha adaptación en clases de taekwondo, entorno en el cual ha sido utilizado exitosamente. La verificación empírica relacionada con la eficacia de la adaptación de este modelo es necesaria.
La culture matérielle des Hongrois en analyse. Décor et mise-en-scène dans les séries télévisées hongroises contemporaines
Authors: Keszeg Anna
Published: November 2019

Au cours de la dernière décennie, la Hongrie est devenue plus visible sur le marché international de la série télévisée: les productions de la chaine HBO et les productions, plus récentes, de RTL Klub contribuent à l'apparition d'une image nouvelle pour la région. L'objectif du présent article est d'analyser le choix et la décoration des lieux d'habitation dans les séries télévisées hongroises. Dans ce but, on présente d'abord les modalités du marché domestique de la production télévisée. Or l’évolution de ce marché ne peut pas être comprise sans aborder dans un premier temps l'histoire des séries dites complexes et le rôle joué par HBO dans leur développement. Les séries analysées, qui appartiennent au genre dramatique (Terápia, Aranyélet, Alvilág), font parti de ce nouveau format. La seconde partie de l'article présente les schémas théoriques d'analyse du décor cinématographique proposés par Charles et Mirella Jona Affron et par Charles Tashiro. En se basant sur les catégories respectives de ces auteurs, l'article montre que les séries hongroises adoptent de plus en plus un modèle caractérisé par une grande attention au design et où les signes de la culture matérielle jouent un rôle essentiel dans le projet de décrire les conflits d'ordre culturel, sociaux et politiques inhérents à la société hongroise contemporaine.
Moderne-Debatten auf der Grundlage des kulturellen Transfers im Pester LLoyd der 1900er-Jahre
Authors: Bognár Zsuzsa
Published: November 2019

Die wichtigste deutschsprachige Tageszeitung Ungarns, der liberale Pester Lloyd (1854–1944) spielte in der Kulturvermittlung zwischen Ungarn und den anderen europäischen Ländern von Anfang an eine entscheidende Rolle. Um die Jahrhundertwende, als Literatur und Kunst den Erwartungen der institutionalisierten volksnationalen Ästhetik untergeordnet wurden, konnte seine Praxis des regelmäßigen Kulturtransfers in Form von kritischen und theoretischen Veröffentlichungen der Moderne zur Etablierung verhelfen. Der Beitrag stellt die einzelnen Etappen dieses Prozesses mit typischen Textbeispielen dar.
The Child Woman in Fin-de-Siècle Vienna
Authors: Biró Annamária
Published: November 2019

The 20th century witnessed an increasing interest in psychoanalysis and, in relation to it, sexual deviances. Vienna had an outstanding role in this interest because it was where Sigmund Freud worked, and where the psychoanalytic society formed by his disciples was also active. In his volume from 1905, entitled Drei Abhandlungen zur Sexualtheorie, he listed certain forms of child sexuality as sexual deviances. At the same time, the arts often represented the child body both in its innocence, but often also as a sexual object. I think that the publication of a novel which was perceived as belonging to the category of child pornography in Vienna in 1906 can also be seen as part of this process, although it has been discussed earlier independently from other cultural or scientific processes of the turn-of-the-century Vienna. My paper attempts to place this novel into the above detailed context.
Cultural Policies. The First Decade of the La Fontaine Literature Society (1920–1930)
Authors: Varga Ildikó P.
Published: November 2019

The La Fontaine Literature Society was founded in 1920 in Budapest. Its task was to promote the world literature in Hungary and to make Hungarian literature better known abroad.

One of the founders was Béla Vikár, who also translated the Fables of Jean La Fontaine into Hungarian. In my paper I investigate his correspondence between 1920 and 30 and the deed of foundation of the La Fontaine Society. My aim is to describe the place and the role of Finnish and Estonian literatures in the Society's work.
Evaluation of vitamin K (menaquinone-7) stability and secretion in glucose and glycerol-based media by Bacillus subtilis natto
Authors: Mahdinia E. , Demirci A. , Berenjian A.
Published: November 2019

Menaquinone-7 (MK-7) is a type of vitamin K. MK-7 is produced via bacterial fermentation, and in order to reach the desired product purity, several downstream processing steps, including extraction, drying, ultrasonication, must be carried out. These processes, however, need to be carried out in such fashion to ensure the least amount of vitamin K lost and maximum recovery into the end-product. Therefore, in this study, drying, storage at 4 and −20 °C, and ultrasonication steps were evaluated under different conditions. Static liquid fermentations were conducted in McCartney bottles to explore the maximum MK-7 secretion potentials in different glycerol and glucose-based media compositions that were optimized in our previous studies. Maximum 32.5±0.4 mg l−1 and 14.6±0.4 mg l−1 concentrations were achieved in glycerol and glucose-based media, respectively. Concentrations of MK-7 produced under same fermentation conditions in 30 ml McCartney amber bottles with 3 ml of media in them and in 75 ml culture tubes with 20 ml media were compared. Also, ultrasonication, drying, and storage conditions were investigated to ensure the least amount of vitamin K is lost. Results showed that drying under forced air flow was the fastest, thus, demonstrated a better preservation of the vitamin, and should replace vacuum drying. Ultrasonication for 15 min seems to be safe and sufficient for phase transition for analysis. Also, storage at refrigerated temperatures seems to preserve MK-7 at least for one week. Furthermore, fermentations in McCartney bottles indicated how MK-7 concentrations are distributed in different zones of the static liquid broth. Culture tube results provided the conclusion as of how the metabolism of MK-7 changes in static fermentation when the scale-up process begins from McCartney bottle to culture tubes. Results in general showed a clearer road map to ensuring better quality and preservation of the valuable end-product, and illuminated more the path to further scaling up of the fermentation process for commercial production of MK-7.
The effects of onion skin powder on the quality of cooked chicken meat patties during refrigerated storage
Authors: Kurt Ş. , Ceylan H. G. , Akkoç A.
Published: November 2019

In this study, the effects of onion skin powder (OSP) (0, 1.5, 3.0, and 6%) on some chemical and physical properties of cooked chicken meat patties during refrigerated storage (30 days, 4±1 °C) were investigated. For this purpose, moisture, fat, pH, free fatty acid (FFA), and thiobarbituric acid (TBA) analyses in the raw meat patties were also carried out. In addition, the chemical (moisture, fat), technological (diameter reduction, cooking yield), and sensory properties of cooked chicken patties were examined on the first day of storage. During storage, pH, colour, FFA, and TBA analyses were performed.

There were significant changes in the physical, chemical, technological, and sensory properties of chicken patties with OSP addition. The moisture, pH, and TBA values of samples decreased by incorporated OSP. Moreover, the use of OSP improved technological parameters of patties. However, the addition of OSP resulted in a darker colour in patties. In conclusion, OSP could be used in chicken meat patties to improve their quality properties.