bluuebunny/crossref_metadata_2025 huggingface dataset:
Hereditary angioedema caused by C1-esterase inhibitor deficiency: a case report with literature-based analysis
Authors: Athar Sufia , Korichi Noureddine , Siam Yousra Shehada
Published: January 2019

Hereditary angioedema (HAE) caused by C1-esterase inhibitor deficiency is an autosomal-dominant disease caused by a mutation in the C1-inhibitor gene. It is a rare disease that is often worsened during pregnancy and childbirth. HAE, though uncommon but if untreated it may lead to maternal death.  The case report presents the successful management of a 24 years old, G2P1, with hereditary angioedema caused by C1-esterase inhibitor deficiency. This patient was managed with a multidisciplinary approach by an obstetrician, an immunologist, an anaesthesiologist and a pediatrician. She had an uneventful antenatal period, labor was induced. She had precipitate delivery and soon after delivery had a flare up of the disease. It was successfully managed with fresh frozen plasma and close observation.
Capillary haemangioma of fallopian tube: a rare but dangerous incidental finding
Authors: Yadav Shakti Kumar , Bhoj Mishika , Salhan Sudha , Sarin Namrata , Singh Sompal
Published: January 2019

Haemangiomas are tumors of vascular origin. They are frequently observed in soft tissue and skin. Vascular tumors of female pelvic organs are extremely rare. Although, majority of these lesions are detected incidentally, they can mimic various benign and malignant lesions clinically and radiologically. Fallopian tube capillary haemangioma is very rare benign neoplasm. Only one case of capillary haemangioma of fallopian tube has been reported. A 44-year-old female with menorrhagia, underwent hysterectomy with bilateral salpingoopherectomy. Both the fallopian tubes were grossly unremarkable. Microscopic examination revealed a well circumscribed vascular neoplasm, consistent with capillary haemangioma, CD34 immunostaining highlighted the vascular endothelium.  Although benign in nature, haemangioma of the fallopian tube can present with complications. Rupture of the haemangioma can be lethal when present with hemoperitoneum.
Post hysterectomy fallopian tube prolapse: a rare case
Authors: S. Priya , C. Sarojamma , P. A. Sailakshmi M.
Published: January 2019

Fallopian tube prolapse into the vaginal vault is a very complication of hysterectomy where the adnexa is preserved. The overall occurrence after all routes of hysterectomy is 0.01-0.05%. Several factors have been suggested to contribute to the condition such as vault hematoma, improper closure of vault, early resumption of sexual activity. Due to the misdiagnosis, there is often delay in the diagnosis and its management. The only means of definitive diagnosis is histopathology. A 30-year-old P2l2 presented to us after 3 years of post-hysterectomy with abdominal pain and bleeding pv on and off. On examination prolapsed fallopian tube was found in the vaginal vault on speculum. Biopsy was done in the outside hospital and was confirmed to be the tube. Patient underwent combined laparoscopic and vaginal method. Vaginal excision of the tube was done. Prevention by prophylactic salpingectomy and by suturing the adnexa high up in the pelvis in abdominal hysterectomy.
Sciatic nerve: Non-union of its components and clinical implication
Authors: Baxla Monica , Krishna Hare , Tandon Rati , Ganapathy Arthi , Kaler Saroj
Published: January 2019

Background: Having prior anatomical knowledge of the anatomical variations is a must for the accurate and effective diagnosis of clinical conditions associated with the sciatic nerve. Sciatic nerve, the longest nerve in the human body has been of great interest for the clinicians and anatomists; though many studies have been conducted in the past to study its anatomical aspect. Till now high division or low formation of the sciatic nerve has been reported but this article highlights the non-union of the components of the sciatic nerve and its clinical outcomes. It had been observed that the common fibular and tibial nerve which arise separately from the sacral plexus remain separated throughout their course. They do not join to form the sciatic nerve. Non-union of the components can result in incomplete blockade of the nerve but selective blockade of one of the components can be done when needed. Aim of the study was to determine the level of formation and the level of division of the sciatic nerve.Methods: Sixty-two lower limbs were taken from the Department of Anatomy, AIIMS, New Delhi and gluteal region was observed for common fibular and tibial nerve and their joining to form the sciatic nerve.Results: Out of 62 lower limbs; 52 specimens showed formation within the pelvis but in 10 specimens the sciatic nerve did not form at any point. Division of the nerve in 52 specimens were at various levels on the posterior aspect of thigh.Conclusions: While giving anaesthesia it’s important to know the formation as well as division of the nerve for an effective lower limb block for various surgical interventions and in case of non union of tibial and common fibular nerve to form the sciatic nerve individual nerve block can be given.
Prevalence of nomophobia and factors associated with it: a cross-sectional study
Authors: Khilnani Ajeet Kumar , Thaddanee Rekha , Khilnani Gurudas
Published: January 2019

Background: Excessive use of mobile phones, including smart phones, is found to result in various health related, social and psychological problems. Nomophobia expands to ‘No Mobile Phobia’, i.e., fear of being out of mobile phone contact. Previous studies on nomophobia have focused on the student populations, since the younger generation is more technology savvy. This questionnaire-based study aimed to know the prevalence and factors leading to nomophobia in general population.Methods: This study was conducted in western Gujarat from September 2018 to October 2018. A prevalidated questionnaire, containing three parts, the demographic details, details about the characteristics of mobile phone use and the Nomophobia Questionnaire (NMP-Q), was sent through emails and WhatsApp to 1000 individuals. The responses were tabulated and analyzed.Results: Out of 331 respondents 192 (58%) were males and 139 (42%) females. There was no significant difference in average NMP scores with respect to gender (p = 0.401), age brackets (p = 0.135), marital status (p = 0.123) and profession (p = 0.055). However, NMP scores were significantly more in individuals who spent more time on mobile phones per day (p = 0.000), checked their mobile phones more frequently (p<0.000) and in whom phantom ringing syndrome was also present (p<0.000). 241 respondents (72.80%) felt that their mobile phone use was consuming time and affecting their other daily activities.Conclusions: Nomophobia is an emerging health related adverse effect of prolonged mobile phone use. Interventions are required to promote judicious use of mobile phones.
Imatinib induced bone marrow hypoplasia in a case of chronic myelogenous leukemia
Authors: Kausar Mehlam , Karpurmath Shashidhar V. , Nandennavar Manjunath I. , Jacob Roshan K. , Angadi Veerendra , Sekar Annalakshmi
Published: January 2019

Imatinib mesylate a tyrosine kinase inhibitor first introduced for the treatment of chronic myelogenous leukaemia (CML) since May 2001, has revolutionised the management of CML. Imatinib is the first choice of treatment for patient with CML chronic phase (CML-CP) and generally the drug is well tolerated. A number of haematological and non-haematological side effects are associated with it. Bone marrow hypoplasia is one of the rare side effects noted with imatinib. We report a case of 46-year-old male a case of CML-CP who developed bone marrow hypoplasia following treatment with imatinib for a period of six months with bone marrow biopsy showing decreased cellularity.
Prevalence and risk factors of hyperpigmentation induced by hydroxychloroquine in lupus patients
Authors: Mleeh Nouf T.
Published: January 2019

Background: Antimalarials including hydroxychloroquine (HCQ) have been used in the treatment of systemic lupus erythematosus (SLE) for more than 50 years. Few cases of hyperpigmentation attributed to HCQ have been reported in the literature from different geographical areas. However, no case reports or local studies from Saudi Arabia estimated the magnitude of HCQ adverse effect. This study aimed to estimate the prevalence of HCQ-induced hyperpigmentation and to investigate the possible risk factors related to this condition.

Methods: This retrospective study was conducted at King Abdulaziz University Hospital. All SLE patients on HCQ treatment, aged 18 years or above who visited Rheumatology and Dermatology Clinics were included. Those with the previous history of hyperpigmentation before starting HCQ treatment, or on chloroquine or quinacrine therapy were excluded. Medical records from September 2005 until June 2016 were reviewed.

Results: Out of 199 cases, 98 (49.2%) cases had hyperpigmentation, only 13 (13.3%) cases reported resolution. The main sites affected were the hands 46 (23.1%), followed by face 45 (22.6%), then feet 18 (9.0%), leg and whole body equally 12 (6.0%). There was a significant association between hyperpigmentation and receiving medications, history of ecchymosis, sun exposure, the presence of mucous membrane pigmentations (p<0.0001, p=0.012, p<0.0001, p=0.022 respectively).
Conclusions: HCQ-induced pigmentation is considered uncommon adverse effect of HCQ, with a prevalence rate of 49.2% indicated in this study. Furthermore, history of bruising, sun exposure, and the presence of mucous membrane pigmentation are possible predisposing factors.
Prevalence of non-infectious dermatoses in patients attending a tertiary care center in Rajasthan
Authors: Singh Bhagirath , Paul Indira Subhadarshini
Published: January 2019

Background: Pediatric dermatoses require a separate view from adult dermatoses as there are important differences in clinical presentation, treatment and prognosis. There is very little epidemiological study available on non-infectious childhood dermatoses in India. The aims of the study were to find the prevalence, clinical profile and various etiological factors associated with childhood non-infectious dermatoses and to determine the prevalence of most common non-infectious childhood dermatoses.

Methods: This cross-sectional observational study conducted at tertiary care centre in Rajasthan, India. Children with age 13 years and below with clinical evidence of cutaneous disorders were studied. Parents who have not given consent for the study, acutely ill children, Children having infectious dermatoses (bacterial, fungal, viral, arthropods, parasitic and protozoal infection) were excluded from the study.

Results: A total of 232 cases were studied which showed a female preponderance of 55.60%. Most of the skin diseases were seen in the 5 to 13 years (school children) age group. The most common dermatoses was eczematous (36.63%), among eczema atopic diathesis was the commonest (17;20%) followed by hypersensitivity dermatoses (21.12%), genetic disorders (13.36%), disorders of genetic disorders (7.4%), sweat gland disorders (8.18%), pigmentary disorders (4.31%), papulo squamous disorders (4.74%), Nevi (6.46%).

Conclusions: Eczematous dermatoses were the most commonly noted in the study, followed by hypersensitivity dermatoses. Atopic diathesis was the commonest endogenous eczemas. Acne, insect bite reaction and miliaria were the other common dermatoses. There was no significant association of various dermatoses with systemic diseases in the study.
A retrospective study of mucocutaneous lesions of SLE patients and their systemic implications
Authors: Ponnurangam Rekha Gurunatham , Kannan Rajkumar , Nallu Kamalanathan , Chandrasekar Muthusubramanian
Published: January 2019

Background: SLE is a systemic disease with multiorgan involvement occuring very rarely, if so, it has a very grave prognosis if not detected early. Our study enlightens about the evolution of mucocutaneous lesions which can serve as an eye opener for early detection of systemic involvement.

Methods: A descriptive study was conducted in the Department of Dermatology at a tertiary care centre from May 2017 to April 2018 retrospectively. From 15 confirmed cases of SLE a critical retrospective analysis of symptom complex evolution was done and thus a clinical correlation of evolution of mucocutaneous lesions and systemic involvement was attempted.

Results: Out of the fifteen patients in our study comprising various age groups (4-51 years), mean age group was 29.76 years. 14 (93%) were female patients and 1 (6.6%) male patient. Oral ulcerations, Non-scarring alopecia and vasculitic lesions were predominant (3 patients-80%) followed by photosensitivity and cheilitis (9 patients- 60%). Systemic involvement was present in 9 (60%), out of which one (6%) patient had lupus nephritis and 3 patients (20%) had CNS lupus, 2 (13%) had chronic unilateral scleritis, 2 (13%) had interstitial lung disease, one (6%) had coronary heart disease. Mucocutaneous lesions preceded the systemic involvement in 88.8% of cases, with mean duration being 3 years (4 months – 10 years).

Conclusions: Mucocutaneous lesions could serve as an eye opener for diagnosis of SLE, which is always a diagnosis made out of high degree of suspicion apart from certain mucocutaneous lesions serving as an ominous sign of system involvement in SLE.

 
The study on association of co-morbidities in female patients with vitiligo
Authors: Sivasubramanian Athilakshmi , Ganapathi Suchithra
Published: January 2019

Background: Vitiligo is an acquired pigmentary disorder of skin characterized by the presence of depigmented patches and macules. Vitiligo has been found to be associated with certain autoimmune diseases like diabetes and hypothyroidism. This study is done to evaluate the association of certain co-morbidities with vitiligo in female patients. The aim of the study was to assess the association of vitiligo with co-morbidities in female vitiligo patients and to find the familial association.

Methods: Retrospective hospital-based study done over a period of 6 months.

Results: In this study series of 75 cases, 19% of cases were associated with hypertension, 25% were associated with diabetes mellitus, 15% were associated with hypothyroidism and positive family history was noted in 17% patients. The mean age of presentation was 43.18.

Conclusions: We found a high association of co-morbidities among female patients with vitiligo. In our study, diabetes has been found to be more commonly associated with vitiligo than other comorbidities. Hence screening for co-morbidities should be considered in vitiligo patients.
KURAL BAZLI MUHASEBEDEN İLKE BAZLI MUHASEBEYE GEÇİŞİN İŞLETMELER AÇISINDAN STRATEJİK ÖNEMİ VE MUHASEBECİLERİN GÖRÜŞLERİ
Authors: YÜREKLİ Emin , SUSMUŞ Türker
Published: January 2019

Küreselleşme
ülkeleri birbirini oldukça büyük bir hızla yaklaştırmakta ve bu durum finansal
piyasaları  daha etkin ve birbirine daha
bağımlı hale getirdiği gözlenmekte ve bunun sonucu olarak da bir ülke veya
piyasada oluşan gelişmeler hızla diğer piyasaları da etkisi altına
almaktadır.  Uluslararası Finansal
Raporlama Standartları ve bu standartların doğru ve ihtiyaca uygun bir şekilde
hazırlanıp sunulması ülkelerin küresel piyasalara uyumu ve entegresyonunda
oldukça önemli bir faktör olduğu bilinmektedir.  UFRS ilke bazlı yaklaşım ile hazırlanmakta olup
bu nedenle daha az kural içermekte ve verdikleri genel ilkeler muhasebe meslek
mensupları tarafından yorumlanmaktadır. Bu durum ‘’mesleki yargı’’ olgusunu ön
plana çıkarmaktadır. Bu çalışmada Denizli ilinde faaliyet gösteren 7 tane
muhasebe meslek mensubuna odak grup çalışması uygulanmış, kural bazlı
muhasebeden ilke bazlı muhasebeye geçiş sürecinde muhasebe uygulamalarındaki
düşünce ve tercihleri ile ilgili bir takım sorular sorulmuş ve bu sorular
doğrultusunda elde etmiş olunan sonuçlar ayrıntılı bir şekilde açıklanmıştır.
Od c-Fos do MMP-9 w kontroli plastyczności synaptycznej zdrowego i chorego umysłu, spojrzenie osobiste
Authors: Kaczmarek Leszek
Published: January 2019

c-Fos is a component of AP-1 transcription factor. Three lines of evidence support pivotal role of c-Fos in learning and memory: (i) learning experience markedly enhances its expression; (ii) blocking od c-Fos impairs, while optogenetic activation of c-Fos expressing neurons supports learning and memory; (iii) c-Fos/AP-1 gene targets in activated neurons, encoding tissue inhibitor of metalloproteinases-1 (TIMP-1) and matrix metalloproteinase 9 (MMP- 9) play a major role in synaptic plasticity that underlies learning and memory. TIMP-1 and MMP-9 compose an extracellularly operating enzymatic system active locally around excitatory synapses to modulate their morphology, molecular content and efficacy. Animal studies have implicated MMP-9 in a variety of neuropsychiatric conditions, e.g., epileptogenesis, autism spectrum disorders, development of addiction, and depression. In humans, MMP-9 contributes to epilepsy, alcohol and cocaine addiction, Fragile X Syndrome, schizophrenia and bipolar disorder. In aggregate, all those conditions can be considered as reflecting either healthy or diseased mind.
Na dobre i na złe â czyli rola oddziaływania trzustki, śródbłonka i tkanki tłuszczowej w regulacji funkcjonowania komórek Î˛ i rozwoju cukrzycy typu 2 związanej z otyłością
Authors: Janikiewicz Justyna , Pawelec Paulina , Kucharczyk Patrycja , Dobrzyń Agnieszka
Published: January 2019

During long-standing obesity and insulin resistance, pancreatic Î˛-cells adapt in order to meet the growing demand of the periphery for insulin. The development of type 2 diabetes requires parallel pathological processes, during which Î˛-cells are continuously exposed to an overabundant supply of specific lipid derivatives. The metabolic events that lead to inevitable Î˛-cell damage are not completely uncovered, and for the time being, our understanding of the dynamic endothelium-adipose tissue-Î˛-cell interactions is limited. Here, we explore various links between continuous obesity, adipose tissue spillover, a dysfunctional endothelium, and defects in islet angioarchitecture to elucidate the crosstalk between signaling systems, cellular mediators, and cell types that contribute to Î˛-cell failure through diverse actions of fatty acids. These molecular and biochemical mechanisms initiate critical rearrangements of the pancreatic vasculature, intraorgan lipid storage capacity, and inflammatory status that subsequently have severe repercussions on Î˛-cell function and promote diabetes.
Metaloproteinaza macierzy pozakomórkowej 9 i epileptogeneza â kluczowa rola enzymu i strategie zmierzające do zapobiegania rozwojowi choroby
Authors: Khomiak Danylo , Kaczmarek Leszek
Published: January 2019

Epileptogenesis is the process responsible for converting normal brain into an epileptic. It may be triggered by an event such as brain injury or status epilepticus (SE). Themain mechanisms responsible include neuroinflammation and blood-brain barrier (BBB) disruption, pathologic neuronal networksâ reorganisation and aberrant synaptic plasticity. Accumulating amount of evidence from animal models and epileptic patients strongly suggest that matrix metalloproteinase 9 (MMP-9) is potentially one of the key executors of the processes of epileptogenesis. MMP-9 by affecting synaptic plasticity is suggested to enable epileptic remodelling of the brain circuitry. MMP-9âs dependent cleavage of BBB followed by inflammatory cell infiltration into the brain contributes to the neuroinflamation component of epileptogenesis. The goal of this review was to analyse all possible ways MMP-9 may be involved in epileptogenesis and consider MMP-9 inhibition as potential therapeutic strategy.
Pęcherzyki transportu wewnątrzkomórkowego i zewnątrzkomórkowego â kluczowe struktury w procesie różnicowania tkanki kostnej i chrzęstnej
Authors: Strzelecka- Kiliszek Agnieszka , Bożycki Łukasz , Komiażyk Magdalena , Dudek Justyna , Gasik Joanna , Pikuła Sławomir
Published: January 2019

Differentiation of cells of the skeletal tissue, such as osteoblasts and chondrocytes, into mineralization-competent cells is a necessary step of the physiological process of bone and cartilage mineralization. Vascular cell calcification accompanies a pathological process of atherosclerotic plaque formation, which occurs due to trans-differentiation of vascular smooth muscle cells into cells resembling bone mineralization-competent cells. The activity of tissue-nonspecific alkaline phosphatase (TNAP), an enzyme necessary for physiological mineralization, is also induced in vascular cells in response to inflammation. TNAP acquires its mineralizing function when anchored to the plasma membrane (PM) of mineralizing cells and to the surface of vesicles derived from these cells. Numerous important reports indicate that various types of vesicles play a crucial role in initiating cell differentiation. In this review, we would like to highlight various functions of different types of vesicular structures of the cellular transport machinery such as intracellular vesicles (IVs), extracellular vesicles (EVs) or matrix vesicles (MVs) at distinct stages of both physiological and pathological processes of tissue differentiation.
Białka z rodziny Vps13 – od funkcji molekularnej do patogenezy chorób neurodegeneracyjnych
Authors: Kamińska Joanna , Kolakowski Damian
Published: January 2019

Grupa białek Vps (ang. vacuolar protein sorting) zaangażowanych w transport do wakuoli została odkryta u drożdży Saccharomyces cerevisiae. Wśród białek Vps, jest rodzina Vps13, której przedstawiciele występują u organizmów z różnych grup systematycznych. U drożdży jest jedno białko Vps13, a u ludzi są cztery Vps13 – hVps13A-D. Są to białka duże, o charakterystycznej budowie domenowej. Mutacje w genach hVPS13 są powiązane z rzadkimi chorobami neurodegeneracyjnymi: pląsawicą-akantocytozą (hVPS13A), zespołem Cohena (hVPS13B/COH1), usposabiają do wczesnej choroby Parkinsona (hVPS13C) i prowadzą do ataksji/kurczowego porażenia kończyn (hVPS13D). Brak jasnych kryteriów diagnostycznych, szerokie spektrum niespecyficznych objawów powodują, że chorzy z neurodegeneracją są często źle diagnozowani i trudno jest określić liczbę pacjentów z mutacjami w genach hVPS13. Istotność białek z rodziny Vps13 dla zdrowia ludzi nakierowuje badania na poznanie ich funkcji molekularnej, która jest nieznana. Badania najczęściej prowadzone są w modelowych układach doświadczalnych, w których wywołano deficyt tych białek na drodze delecji lub wyciszenia ekspresji odpowiednich genów oraz na komórkach pochodzących od pacjentów. Opisano wiele zmian na poziomie komórkowym  wywołanych brakiem  białek Vps13, które dotyczą transportu komórkowego białek między cysternami aparatu Golgiego, błoną komórkową i endosomami, funkcjonowania mitochondriów i organizacji cytoszkieletu komórkowego, głównie aktynowego. Nie wiadomo jednakże, które zmiany są zmianami pierwotnymi, a które wtórnymi, kompensacyjnymi. Ostatnio badania na drożdżach pokazały Vps13, jako białko zlokalizowane w miejscach kontaktu błon, strukturach zapewniających wymianę metabolitów między różnymi organellami. Taka lokalizacja wydaje się być kluczowa dla funkcji Vps13. Na podstawie danych literaturowych proponujemy hipotezę o aktywnym udziale białek Vps13 w wymianie lipidów między błonami organelli w miejscach kontaktu błon, która tłumaczy większość fenotypów obserwowanych przy  braku białka Vps13.
Genodermatozy – patogeneza i diagnostyka molekularna
Authors: Wertheim- Tysarowska Katarzyna
Published: January 2019

Genetycznie uwarunkowane choroby skóry, genodermatozy, stanowią grupę rzadko występujących chorób o wysoce zróżnicowanym przebiegu klinicznym, rokowaniu izłożonej patologii molekularnej. Pęcherzowe oddzielanie się naskórka (EB) i zaburzenia rogowacenia o dziedziczeniu Mendlowskim (MeDOC) to genodermatozy, w których dochodzi do zaburzeń funkcjonowania naskórka. Zidentyfikowano już kilkadziesiąt genów przyczynowo związanych z występowaniem objawów klinicznych, a więc, w ogólnym ujęciu, tendencji do tworzenia pęcherzy i nadmiernej podatności skóry na urazy w przypadku EB oraz nieprawidłowego rogowacenia w MeDOC. Objawy kliniczne tych chorób mogą być jednak bardzo zróżnicowane, a zależności genotypowo-fenotypowe określone zostały tylko częściowo. Diagnostyka molekularna, której celem jest identyfikacja mutacji u poszczególnych pacjentów umożliwia weryfikację rozpoznania klinicznego, określenie ryzyka powtórzenia się choroby w rodzinie, a stopniowo także podstawę do opracowania nowych terapii. Jednakże, nawet nowoczesne technologie analizy molekularnej pozwalają na wykrycie mutacji tylko u 80% chorych. Określenie patologii molekularnej w przypadku pozostałych pacjentów oraz opracowanie skutecznych terapii wymaga dalszych, interdyscyplinarnych badań naukowych.
The relationship between emotional appetite and bipolar features in obese and non-obese individuals
Authors: BUDAK Ersin , TAYMUR İbrahim , ÖNEN Sinay , ÇAYCI Hacı Murat , ŞENORMANCI Güliz
Published: January 2019

Objectives: It is known that many different positive
and negative emotions can affect appetite and also, individuals who have
bipolar features often have emotional fluctuations. In this study, it was aimed
to investigate the relationship between emotional appetite and bipolar features
in obese individuals. Methods: One
hundred and ninety
obese individuals who applied for bariatric surgery and 136 non-obese
individuals were evaluated with Emotional Appetite Questionnaire (EMAQ), Beck-
Depression Inventory (BDI), Beck-Anxiety Inventory (BAI) and The Temperament
Evaluation of Memphis, Pisa, Paris and San-Diego Auto-questionnaire (TEMPS-A)
in the study. Results: In obese individuals who applied for
bariatric surgery, the frequency of bipolar disorder was found to be 2% and
binge eating disorder (BED) frequency was 51.2%. It was found that scores of
appetite in negative emotions were higher in obese individuals with BED
compared to obese individuals and it was higher in obese individuals compared
to normal weight individuals. Cyclothymic features explained 27.2%, 25.8% and
15.7% of scores of appetite in negative situations of obese individuals with
BED, obese individuals without BED and normal weight individuals, respectively.

Conclusions:
As a result of this study, it can be concluded that
scores of appetite in negative situations may be affected by cyclothymic
features in obese individuals with BED, in obese and normal weight individuals.
Depression and anxiety symptoms are effective factors in explaining scores of appetite
in negative situations of obese individuals with BED, obese and normal weight
individuals.
Humor dalam Pembelajaran “Tinjauan Penelitian Humor di Kelas”
Authors: Mukhlis Akhmad
Published: January 2019

This article is a summary of research on Instructional humor. The analysis conducted on several journal articles and books to find identification and explain the inconsistencies in the results of research. First, the communication will be reviewed on the basis of humor. This section describes the definition, theory and function of humor in learning both in the psychological perspective and student's academic achievement. Second, an overview of the research results in a quantitative and qualitative perspective. Frequency of use of humor, kind humor and appropriateness for classroom. Lastly, discussions were conducted to see the potential humor and suggestions for teachers in the classroom.
Perilaku Siswa Sekolah Dasar dalam Menyelesaikan Soal Cerita Matematika
Authors: Yuliandari Ria Norfika
Published: January 2019

Learning word problem can be used as a means to drill students to solve problems. In word problem, students are demanded to be able to comprehend problems contexts that are given, make Math model from those problems, find ways to solve them and re-examine the results gotten. While in fact, it is shown that there are still a lot of students who find difficulties so that they make some errors in solving word problems. Related to the wills that appear to know the students’ behaviour and errors that are done by students while solving word problem by using Polya solving problem model. This study is focused to identify and classify errors that are done by students in solving word problems.. In addition, the reasons why the errors occur and hoe to solve them are going to be revealed here. This study uses qualitative descriptive approach. This research is done by students of fifth graders in SDN 1 Kebonsari Malang. The subjects of this study are chosen through the entrance test with errors variations and discussion results with teachers. There are eight students that are chosen who are divided into two students who have high ability, two students who have medium ability and four students who have low ability. Behaviour, types of errors and the reasons are gotten from the result of test and interview. The behaviour that is shown by the students of fifth graders in SDN 1 Kebonsari Malang are classified into four categories such as DTA-not proficient and DTA-proficient. Moreover, it is also found that there are other different reasons occur, but they are still related to the Pape behaviour problem solving, that is DTA-Limited Context + behaviour translation but without explanation, DTA Proficient + behaviour translation and DTA-Not Proficient + behavior translation. Based on the result of the study, it is suggested that teachers should know the errors that are often done by the students before the lesson begins to emphasize the teaching and learning process in those errors. Teachers are also able to give some practices, mainly in word problem to drill students’ experiment in solving them. Furthermore, the steps of solving the problems by using Polya model need to emphasize in terms of its usage so that it can practice students’ thinking process systematically. For the further research, if other researchers want to use this model to conduct further research so that they need to consider the application of this method in students and schools’ condition that are relatively different or other Math topics in the same subject.
Pengembangan Komik Sains untuk Siswa Sekolah Dasar/Madrasah Ibtidaiyah Menuju Banjarmasin Siaga Banjir
Authors: Cahyadi Ani , Ningsih Murni , Islamy M. Irfan
Published: January 2019

Banjarmasin as a lowland city, many small, medium, and large rivers, the majority of swamp areas, would be interesting to be used as an object in education as a place to learn about the knowledge and cultures of the river that characterized by region. The right place is education, especially elementary school which is the most appropriate target in instilling awareness on early. World of education, learning will be interesting if the media are included to make students more excited in the learning process. Comics contained illustration of character, scene, and groove usually arranged as entertainment. in this research developed in the form of science comic based on disaster mitigation, that is flood disaster with hope to be as educative media of learning also as entertainment for student. This research uses model of ADDIE media product development. The research developing two comic entitled "Amang si Pembelajar" and "Belajar Siaga Banjir (BSB)" with good quality in terms of material with a score of 3.22 and excellent quality in terms of learning media with the final average of 3.3. Science comics based on flood mitigation is full color and in accordance with the needs of primary school
Implementasi Nilai Nilai Karakter Siswa pada Pembelajaran PJOK di Madrasah Ibtidaiyah
Authors: Widodo Bintoro
Published: January 2019

Pendidikan karakter adalah landasan awal untuk menciptakan generasi yang mempunyai moral ataupun akhlak yang mulia. Pendidikan karakter menjadi hal yang sangat diutamakan khususnya pada masa perkembangan anak sekolah. Pendidikan karakter membentuk siswa untuk mencontoh toladan yang baik dengan memahami figur Rasulullah SAW. Pendidikan Karakter dapat diterapkan melalui materi pembelajaran yang ada di sekolah, tidak terkecuali pelajaran PJOK. Pelajaran PJOK bisa menjadi bagian terpenting dalam pembentukan karakter dan perilaku anak. Melalui Pendidikan Jasmani siswa dikenalkan dengan pemahaman rasa tanggung jawab, sportifitas, jujur, adil dan penerapan nilai sosial. Hal ini menjadi penting dan perlu dilakukan oleh seorang pengajar Pendidikan jasmani di Sekolah khususnya di tingkat Madrasah Ibtidaiyah. Pendidikan Madrasah ibtidaiyah merupakan masa usia pembelajaran dasar yang bertujuan untuk membangun dasar karakter pada usai perkembangan anak untuk menuju masa perkembangan selanjutnya. Semakin baik guru membangunkarakter siswa maka akan memberikan manfaat berarti bagi perkembangan anak menghadapi perkembangan usia dewasa.
Pembelajaran Bahasa Arab di MIN 13 Kabupaten Banjar Kalimantan Selatan
Authors: Mahmudah Mahmudah , Masyitah Siti , Zubaidah Zubaidah
Published: January 2019

Tujuan penelitian ini untuk mendeskripsikan proses kegiatan belajar dan mengajar Bahasa Arab di MIN 13 Banjar dan mengetahui ruang lingkup pembelajaran Bahasa Arab di MIN 13 Banjar. Penelitian ini merupakan penelitian deskriptif kualitatif. Pengambilan data menggunakan beberapa teknik pengumpulan data, yaitu: observasi untuk mengamati proses pembelajaran pasa saat proses belajar dan mengajar Bahasa Arab yang berlangsung di kelas, dokumentasi untuk menganalisis ruang lingkup materi Bahasa Arab, dan wawancara dengan guru Mata Pelajaran Bahasa Arab untuk menggali data proses pembelajaran. Analisis data dalam penelitian ini dilakukan dalam tiga tahap, yaitu reduksi data, penyajian data, dan penarikan kesimpulan.Berdasarkan penelitian yang dilakukan maka didapatkan hasil sebagai berikut: proses pembelajaran menyangkut perencanaan proses: dilakukan dengan pembuatan silabus dan rencana pelaksanaan pembelajaran (RPP) dan pembelajaran diusahakan sesuai dengan apa yang telah direncanakan sehingga pembelajaran dapat berjalan sistematis. Ruang lingkup pelajaran Bahasa Arab di Madrasah Ibtidaiyah meliputi beberapa tema yaitu: perkenalan, peralatan sekolah, profesi, alamat, keluarga, anggota btubuh, di rumah, di kebun, di sekolah, di perpustakaan, di kantin, jam, kegiatan sehari hari, pekerjaan, rumah, dan rekreasi.
Konsepsi Penerapan Keterampilan Proses Sains (KPS) dan Sikap Ilmiah Dalam Desain Pengembangan Modul Panduan Eksperimen Ipa SD/MI
Authors: Fiteriani Ida , Baharuddin Baharuddin
Published: January 2019

This research moved from the problem of the lack of availability of science books (modules) based on the development of science process skills (scienific process) and scientific attitude of students. Generally textbooks that are often used by teachers or students emphasize mastery of science concepts (scientific knowledge), while science process skills (scienific process) and what scientific attitudes to be developed are not clearly defined and detailed, so that the impact on activity and acquisition of student learning outcomes. Based on the description of the above problems, the purpose of this research and development is to produce a product in the form of an experimental module for science in elementary school that based on science process skills (scienific process) and scientific attitudes, expecially in term : Human Circulatory System. The model used refers to Borg and Gall. To assess the feasibility of the module, validation was carried out by experts (material experts, media experts, and linguists) and also involved education practitioners. To assess the attractiveness of the module a trial was conducted, which began with a small group and then in a large group. Furthermore, the process of data analysis uses quantitative and qualitative techniques. The research and development (R D) results are 1) The development step begins with analyzing potential and problems, collecting data / information, designing products, validating products, revising products, conducting product feasibility trials, and revising products again. 2) Based on the results of validation and feasibility tests, the development of the science module experiment for SD / MI based on science process skills (scienific process) and scientific attitudes in the term of the Human Circulatory System successfully meet the level of feasibility and attractiveness, therefore it can be used as teaching material in science learning in elementary school (SD/MI)
PERSEPSI SISWA SMK TENTANG KETERAMPILAN MENGAJAR MAHASISWA PKM PROGRAM KEAHLIAN TEKNIK BANGUNAN
Authors: Julianti Regita , Iriani Tuti , Murtinugraha R Eka
Published: January 2019

This research aimed to understand studentsâ€™ perception about PKM students teaching skills majoring in building technique. The research took places in SMKN 1 Jakarta, SMKN 4 Jakarta, SMKN 26 Jakarta, SMKN 35 Jakarta, SMKN 58 Jakarta, and SMKN 1 Cibinong in between April-May 2015.The method used in this research is the Survey method. The subjects of this research were the student from the 10th grade that are taught theoretically by the teachers from the PKM program from Civil Engineering, State University Of Jakarta 102 semester, while the population consists of the student from SMKN 1 Jakarta, SMKN 4 Jakarta, SMKN 26 Jakarta, SMKN 35 Jakarta, SMKN 58 Jakarta, and SMKN 1 Cibinong Program Building Engineering expertise as much as 532 students in those vocational schools, and 221 samplers were taken by purposive sampling method. The instruments used in this research to collect the data about the students perception, are questionnaire about students perception on PKM students teaching skills majoring in building technique. The data processing is valid and reliable, with very high reliability number of r11= 0,956, with 32 numbers of questions.The result shows that the PKM students are skilled already in questioning (85%), giving variation (68%), explaining (67%), class management (72%), starting and closing the lesson (69%), guiding small groups (67%), and teaching small groups and individual (70%). Yet in giving reinforcement, it is still considered as low (49%).
Penggunaan Media Pembelajaran Berbasis Audio Visual untuk Mata Pelajaran Konstruksi Bangunan
Authors: Rinaldi Anggi Aris , Daryati Daryati , Arthur Riyan
Published: January 2019

Penelitian ini bertujuan untuk mengetahui peran media pembelajaran berbasis audio visual dalam meningkatkan hasil belajar siswa pada mata pelajaran konstruksi bangunan pada siswa kelas X TGB di SMK Negeri 56 Jakarta. Penelitian berlangsung dari November 2016 sampai dengan Januari 2017.
Metode yang digunakan dalam penelitian ini adalah metode eksperimen dengan bentuk penelitian nonequivalent control group design, yaitu penelitian yang dilakukan dalam satu populasi yang telah dibagi menjadi 2 kelompok. Kelompok kelas eksperimen diberikan perlakuan media audio visual sedangkan untuk kelas kontrol diberi perlakuan media konvensional, selain itu media pembelajaran yang dibuat divalidasi terlebih dahulu oleh beberapa ahli untuk mendapatkan kelayakan uji coba. Selanjutnya uji coba dilakukan pada peserta didik kelas X bidang keahlian Teknik Gambar Bangunan di SMK Negeri 56 Jakarta yang berjumlah 56 siswa. Analisis data menggunakan uji-t dua pihak sample independen melalui program aplikasi SPSS 23.
Hasil penelitian ini adalah: Berdasarkan nilai hasil belajar yang diperoleh, pada kelas eksperimen rata-rata nilai pre-test sebesar 55,79 dan terjadi peningkatan yang signifikan di hasil post-test dimana pada kelas eskperimen mendapatkan nilai rata-rata sebesar 89,54. Sedangkan untuk kelas kontrol rata-rata nilai pre-test yang diperoleh sebesar 62,39 dan pada saat post-test memperoleh nilai rata-rata sebesar 82,61. Kelas eksperimen memperoleh selisih rerata hasil belajar  (pre-test & post-test) ilmu bahan bangunan sebesar 33,75 dan peningkatan yang terjadi sekitar 16,88%. Sedangkan pada kelas kontrol, selisih rerata hasil belajar (pre-test & post-test) ilmu bahan bangunan sebesar 20,22 dan peningkatan yang terjadi sebesar 10,11%. Maka hal tersebut mengindikasikan bahwa penggunaan media audio visual turut berperan dalam peningkatan hasil belajar siswa pada kelas eksperimen. Maka dapat disimpulkan bahwa terdapat pengaruh positif terhadap penggunaan media audio visual dalam meningkatkan hasil belajar dalam mata pelajaran konstruksi bangunan pada siswa kelas X TGB di SMK Negeri 56 Jakarta
Bridging Geomechanical and Geophysical Numerical Modeling: Evaluation of Seismic Efficiency and Rupture Velocity with Application to Estimating the Fractured Network Generated by Hydraulic Fracturing
Authors: Sheibani Farrokh , Hager Bradford
Published: January 2019

Microseismic monitoring is generally the most reliable method for estimating stimulated fractured volume. Receivers used in microseismic monitoring measure only seismic events. That limitation explains why only a small portion of the energy budget during hydraulic fracturing can be estimated by information obtained from microseismic monitoring.

We performed a series of numerical experiments to investigate the effects of rock mechanical properties and fracture friction characteristics on seismic efficiency and rupture velocity. We conducted numerical experiments using acoustic emission for saw-cut samples under triaxial loads and applied slip-weakening constitutive modeling for natural fractures to study how the Young's modulus and slip-weakening distance affect seismic efficiency and rupture velocity. Perhaps surprisingly, our results show that rocks with higher values of the Young's modulus have lower seismic efficiency generated from sliding on pre-existing natural fractures, while lower rigidity leads to higher seismic efficiency. These results do not contradict general beliefs about the effect of rigidity on fracability. More rigid rocks are more favorable for hydraulic fracturing and generate larger fracture networks; however, compared with less rigid rocks, fewer events would be detected seismically. The results also give insight into how to connect geomechanical numerical modeling of hydraulic fractures in naturally fractured reservoirs with microseismic data from the field and actual subsurface-generated fractured networks.
Power Law Correlation for Slickwater Proppant Dune Height
Authors: Alotaibi Msalli , Miskimins Jennifer
Published: January 2019

Poor proppant transport in slickwater is an industry challenge in the hydraulic fracturing of unconventional reservoirs. Part of this challenge is the difficulty in estimating the settled proppant dune height inside induced fractures. An experimental study was conducted and used to develop lab-based correlations that can predict slickwater proppant dune height as a function of certain key parameters.

A slot flow apparatus was designed and used to conduct more than 70 experiments to obtain the data necessary for the correlation development. The designed fracture slot has a rough surface and is 23.25 inches high and 0.2 inch wide. White sand was tested over a wide range of field representative values for slurry velocity and proppant size and concentration.

Power law correlations were developed for slickwater proppant dune height based on slurry velocity, proppant size, and concentration. The slurry velocity refers to the initially slurry velocity before proppant starts to settle inside the induced fracture. The overall correlation was developed by experimentally studying the effect of each parameter on the dune height and then combining them all in one correlation based on their respective relationships. The developed correlation covers proppant sizes ranging from 100 to 20/40 mesh and concentrations ranging from 0.25 to 2.80 ppg. The developed correlation showed high prediction accuracy relative to obtained lab data with an average error value of less than 0.6% relative to lab data. The developed correlation was further evaluated for its accuracy relative to lab data and the previously published correlation by Wang et al. (2003).

The developed correlation is the first of its type to be based on experimental data while using rough surface slot walls. Roughness is proven to have a considerable effect on proppant settling which makes this correlation more representative for field applications. Also, compared to the well-known correlation by Wang et al. (2003), this correlation covers a wider range of proppant sizes, concentrations, and slurry velocities.
Close Encounters in the 3rd Dimension: Using Diagnostic Fracture Injection Tests DFITs from the Alberta Duvernay Shale Formation to Quantify Simultaneous Horizontal- & Vertical-Plane Hydraulic Fracture Growth
Authors: Nicholson A. Kirby , Hawkes Robert V. , Bachman Robert C.
Published: January 2019

This paper will benefit engineers and geoscientists interested in creating representative hydraulic fracture simulation models and optimizing commercial-scale fracture treatments. The paper focuses on the emerging Duvernay shale formation in Alberta, Canada. Well fracturing pressures are often significantly higher than the Overburden (OB, lithostatic) pressure. Pressures above OB likely create horizontal (hz) bedding plane fracture components since sedimentary rocks are almost always weaker along bedding planes. Most fracture design simulators do not account for the simultaneous existence of multi-plane fractures (Figure 1). Therefore, scaled treatment designs for optimizing fluids, proppant schedules and production performance may be flawed. A key question is: What proportion of the overall fracture volume do horizontal-plane features take? The answer can be sought using the Pressure Transient Analysis (PTA) workflow for Diagnostic Fracture Injection Tests (DFITs) described by Bachman et al (2012, 2015) combined with simple PKN and GDK fracture models to represent the hz and vertical plane fracture components.

DFIT analysis techniques and interpretation are hotly debated topics of late. The authors believe a portion of the gap in the understanding of how hydraulic fractures behave is a result of assuming fracture components are fully, or dominantly, vertical. Analysts often interpret high fracturing pressures as tortuosity or near-well friction. However, during the fall-off period after pumping a DFIT, pressures above OB can persist for up to 20 minutes after pump shut-down. Analysis of these tests often exhibit early-time radial flow signatures which are coincident with the OB gradient of ~22kPa/m (1psi/ft) also indicative of hz plane fractures. In Nicholson et al 2017 four field DFIT examples were presented showing strong evidence of hz plane fractures in various depths and formations found in the Western Canadian Sedimentary Basin.

In the current paper DFIT PTA analysis is applied to two West Shale Basin Duvernay datasets. A physical model is presented (Figure 1) that incorporates the in-situ stress regime, rock fabric, and pore pressure and that allows history matching of DFIT leak-off and closure behavior for fractures above OB pressure. Simple calculations are provided to estimate the volume and dimensions of these same components for a small volume, single viscosity, no-proppant injection DFIT. This unique approach provides a valuable calibration point for building more advanced simulation models.