bluuebunny/crossref_metadata_2025 huggingface dataset:
Rethinking Knowledge Creation in Information Technology and Tourism
Authors: Cai Wenjie , McKenna Brad , Wassler Philipp , Williams Nigel
Published: August 2020

This letter is a rejoinder to Xiang, Fesenmaier, and Werthner (2020), who responded to our letter to the editor about knowledge creation in information technology and tourism (ITT) research (Cai and McKenna 2020). We believe the authors have misinterpreted our claims and failed to address our main points in relation to the lack of theoretical and methodological development of ITT. Therefore, we address and clarify some misunderstandings in their response. We also elaborate on our ideas for broadening the paradigmatic boundaries of ITT research and opening up potential topics to tackle wider social issues. In addition, we provide more guidance for the growth and development of ITT through broadening boundaries, methodology and theorizing, as well as knowledge dissemination.
Where You Labor Is Where You Sing: The New Folksong Movement of 1958 and the Fissured Mediascape of Maoist China
Authors: McConaghy Mark
Published: August 2020

This article examines the New Folksong Movement (NFM) of 1958–1959, which was launched by the Chinese Communist Party in conjunction with the Great Leap Forward (GLF) campaign. It employs an analytical strategy called fissured reading, whereby a discursive assemblage that seems ideologically uniform can be made to reveal the myriad tensions that its own positive facade works to conceal. While the NFM seems suffused with songs of praise for the GLF, closer inspection reveals a project riven with tensions regarding the creative agency of the people, the persistence of “old” songs in popular culture, and dialects. Such methodological concerns were in fact foundational to modern folk study in China as it developed from the 1920s onward. Understanding such historical connections can help us rethink the cultural revolutions in modern China as fissured projects, with tense cracks just beneath their surface that indicate unresolved contradictions passed on from one generation of reformers and revolutionaries to the next.
Leader-following consensus of second-order multi-agent systems with time-varying delays and arbitrary weights
Authors: Shi Lin , Xie Dongmei
Published: August 2020

Using Lyapunov first method instead of traditional Lyapunov second method, this paper focuses on studying the consensus tracking control problem of multi-agent systems (MASs) with time-varying delays and arbitrary adjacent weights under fixed topology and switching topology, respectively. We first give four equivalent criteria for MASs with fixed communication topology, where the positive stability of matrix [Formula: see text] ( L is the Laplacian matrix of [Formula: see text], B is the leader’s adjacency matrix) not only plays a key role as usual but also becomes an urgent and more complicated problem due to the introduction of negative weights in MASs. Second, for MASs with switching communication topology if the average dwell time of switching topology, the total activation time of stable subsystems and the upper bound of time delay satisfy some conditions, then MASs with all stable subsystems (partially stable subsystems) can achieve consensus tracking. Finally, simulations are given to demonstrate the effectiveness of our theoretical results.
The Utility of Gastrointestinal Endoscopic Examination Versus Positron Emission Tomography–Computed Tomography in the Detection of Second Primary Lesions in Korean Patients With Head and Neck Cancer
Authors: Kim Min-Su , Song In Sik , Oh Kyoung Ho , Cho Jae-Gu , Baek Seung-Kuk , Woo Jeong-Soo , Jung Kwang-Yoon , Kwon Soon Young
Published: August 2020

Objective:

Head and neck cancer often accompany a synchronous secondary primary lesion in the digestive tract. The aim of this study was to compare detection rates between positron emission tomography–computed tomography (PET-CT) and esophagogastroduodenoscopy (G-fiber) or colonoscopy (C-fiber) in the initial staging and to analyze risk factors for premalignant, malignant, and total synchronous secondary primary lesions.

Methods:

A total of 739 patients with head and neck cancer who underwent PET-CT, G-fiber, or C-fiber were analyzed retrospectively.

Results:

Positron emission tomography–CT did not definitely detect any premalignant synchronous secondary primary lesions (0 [0%] of 739) but definitely detected 10 malignant synchronous secondary primary lesions (10 [1.35%] of 739). Esophagogastroduodenoscopy or C-fiber detected all 20 premalignant synchronous secondary primary lesions (20 [2.71%] of 739) and all 37 malignant synchronous secondary primary lesions (37 [5.00%] of 739). The patients with nasopharynx cancer tended to have premalignant synchronous secondary primary lesions (odds ratio [OR]: 3.793; 95% CI: 1.414-10.171; P = .008). Those with distant metastasis tended to have premalignant (OR: 4.743; 95% CI: 1.508-14.916; P = .009), malignant (OR: 3.803; 95% CI: 1.486-9.731; P = .005), and total synchronous secondary primary lesions (OR: 2.753; 95% CI: 1.159-6.538; P = .022).

Conclusions:

Premalignant or malignant synchronous secondary primary lesions that were not definitely detected by PET-CT could be found in the endoscopic examination.
A Rare Case of Primary Neuroendocrine Carcinomas in the Ear and Throat and Review of Literatures
Authors: Ma Tianyu , Wang Chunrui , Qin Xiaowei , Zhang Tianhong
Published: August 2020

The neuroendocrine carcinomas (NECs) of the head and neck are rare. The purpose of this article is to explore the diagnosis and treatment of NECs in the ear and larynx. We report a case of a patient with NECs found in the ear and throat simultaneously, and the relevant literatures are reviewed. It is difficult to identify which is the original site. There is no specific clinical manifestation of NECs in the ear and throat, and carcinoid syndrome is a rare situation. Surgery is still the preferred treatment for this disease. For patients with metastasis, radiotherapy and/or chemotherapy are required.
Cognitive-Affective Inconsistency and Ambivalence: Impact on the Overall Attitude–Behavior Relationship
Authors: Conner Mark , Wilding Sarah , van Harreveld Frenk , Dalege Jonas
Published: August 2020

This research explored whether overall attitude is a stronger predictor of behavior when underlying cognitive-affective inconsistency or ambivalence is low versus high. Across three prospective studies in different behaviors and populations (Study 1: eating a low-fat diet, N = 136 adults, eating five fruit and vegetables per day, N = 135 adults; Study 2: smoking initiation, N = 4,933 adolescents; and Study 3: physical activity, N = 909 adults) we tested cognitive-affective inconsistency and ambivalence individually and simultaneously as moderators of the overall attitude–behavior relationship. Across studies, more similar effects were observed for inconsistency compared with ambivalence (in both individual and simultaneous analyses). Meta-analysis across studies supported this conclusion with both cognitive-affective inconsistency and ambivalence being significant moderators when considered on their own, but only inconsistency being significant when tested simultaneously. The reported studies highlight the importance of cognitive-affective inconsistency as a determinant of the strength of overall attitude.
Australian action to reduce health risks from radon
Authors: Long S.A. , Tinker R.A.
Published: August 2020

In Australia, worker exposure to radon in underground uranium mines has been a focus of policy makers and regulators, and has been well controlled in the industry sector. That cannot be said for public exposure to radon. Radon exposure studies in the late 1980s and early 1990s demonstrated that the levels of radon in Australian homes were some of the lowest in the world. The International Basic Safety Standards, published by the International Atomic Energy Agency, requires the government to establish and implement an action plan for controlling public exposure due to radon indoors. When considering different policy options, it is important to develop radon prevention and mitigation programmes reflecting elements that are unique to the region or country. The Australian Radon Action Plan is being considered at a national level, and presents a long-range strategy designed to reduce radon-induced lung cancer in Australia, as well as the individual risk for people living with high concentrations of radon. In Australia, workers who are not currently designated as occupationally exposed are also considered as members of the public. In the Australian context, there are only a limited set of scenarios that might give rise to sufficiently high radon concentrations that warrant mitigation. These include highly energy efficient buildings in areas of high radon potential, underground workplaces, workplaces with elevated radon concentrations (e.g. spas using natural spring waters), and enclosed workspaces with limited ventilation. The key elements for a successful plan will rely on collaboration between government sectors and other health promotion programmes, cooperative efforts involving technical and communication experts, and partnering with building professionals and other stakeholders involved in the implementation of radon prevention and mitigation.
Video Modeling for High School Students With Autism Spectrum Disorder
Authors: Galligan Megan R. Ledoux , Suhrheinrich Jessica , Kraemer Bonnie R.
Published: August 2020

Video modeling (VM) has demonstrated efficacy in teaching a variety of skills (e.g., social skills, communication, vocational tasks) to learners with autism spectrum disorder. Previous research indicates teachers and learners have supported the use of VM. However, the majority of studies have focused on elementary-school students; less research has explored the use of VM in secondary education settings. To extend the literature, this article describes the use of VM with three high school student–teacher dyads. Each teacher adapted the VM intervention to meet the needs of their student as well as to fit with the current technology available and utilized in their classrooms. All of the three students learned a different target skill with VM and achieved mastery criteria. Results for the three student skills, as well as implementation guidelines and future directions, are discussed.
REDI: Towards knowledge graph-powered scholarly information management and research networking
Authors: Ortiz Vivar José , Segarra José , Villazón-Terrazas Boris , Saquicela Víctor
Published: August 2020

Academic data management has become an increasingly challenging task as research evolves over time. Essential tasks such as information retrieval and research networking have turned into extremely difficult operations due to an ever-growing number of researchers and scientific articles. Numerous initiatives have emerged in the IT environments to address this issue, especially focused on web technologies. Although those approaches have individually provided solutions for diverse problems, they still can not offer integrated knowledge bases nor flexibility to exploit adequately this information. In this article, we present REDI, a Linked Data-powered framework for academic knowledge management and research networking, which introduces a new perspective of integration. REDI combines information from multiple sources into a consolidated knowledge base through state-of-the-art procedures and leverages semantic web standards to represent the information. Moreover, REDI takes advantage of such knowledge for data visualisation and analysis, which ultimately improves and simplifies many activities including research networking.
Effects of Occlusion and Conductive Hearing Loss on Bone‐Conducted cVEMP
Authors: Rotem Betito Hadar , Himmelfarb Mordechai , Handzel Ophir
Published: August 2020

Objective

To evaluate the effects of conductive hearing loss and occlusion on bone‐conducted cervical vestibular evoked myogenic potentials (cVEMPs).

Study Design

Prospective cohort study conducted in the year 2018. The right ear of each volunteer was evaluated under 3 conditions by using bone‐conducted cVEMPs: normal (open external auditory canal), occluded (conductive hearing loss with occlusion effect), and closed (conductive hearing loss without the occlusion effect).

Setting

Single academic center.

Subjects and Methods

The study comprised 30 healthy volunteers aged 20 to 35 years (16 women, 14 men). All had normal hearing and no vestibular or auditory pathologies. The thresholds and amplitudes of cVEMP responses were recorded for the 3 conditions. The results of each condition for a particular participant were compared.

Results

As compared with the open condition, the conductive condition increased thresholds by 2.8 dB (P =. 01), and the occluded condition decreased thresholds by 3.8 dB (P =. 008). The amplitude in the occluded condition was larger than the normal condition and the conductive condition (mean difference: 20.64 [P =. 009] and 31.76 [P <. 001], respectively)

Conclusion

The occlusion effect is present in cVEMP responses. The mechanism is not due to the conductive hearing loss induced. Clinical implications include potentially altering vestibular function with sealed hearing aids and in the surgically modified ears (ie, obliterated ears and open cavity mastoidectomy).
Independent walking and balance in children with CHARGE syndrome
Authors: Haibach-Beach Pamela , Perreault Melanie , Lieberman Lauren , Foster Elizabeth
Published: August 2020

Children with CHARGE syndrome (CWCS) are born with multiple physical disabilities, several of which impair balance and the onset of motor milestones. Early motor development problems can include delayed independent walking, which has been found in CWCS. In addition, few studies have examined balance in CWCS and these studies have been limited in scope, necessitating a more comprehensive examination of balance in this population. Motor development occurs as a progression of stages as represented by Seefeldt’s conceptual model. As such, it is essential to examine the association of early development of foundational skills, such as balance, with the onset of motor milestones as they are building blocks to motor competence. The aims of this study are to (1) examine the differential effects of children with and without CHARGE syndrome on balance and (2) examine the association of age of walking to these balance measures. In this study, 27 CWCS and 22 children without CHARGE syndrome, aged 7 to 16 years, were assessed on four components of balance including anticipatory control, reactive postural control, sensory orientation, and dynamic gait using the shortened version of the Balance Evaluation Systems Test (mini-BESTest) and parental reported age of independent walking. Their balance and age of walking were compared to 22 typically developing peers of similar age and gender distribution. Results revealed that CWCS walked three times later than their peers without CHARGE syndrome and had significant deficits on all balance systems assessed with the largest difference occurring in anticipatory control. Anticipatory control is critically important in maintaining static and dynamic postural control. These results indicate a critical need for early functional balance training and compensatory strategies in CWCS.
Segmental saphenous ablation for chronic venous disease treatment
Authors: Gianesini Sergio , Menegatti Erica , Occhionorelli Savino , Grazia Sibilla Maria , Mucignat Marianna , Zamboni Paolo
Published: August 2020

Background

Endovenous thermal ablation for chronic venous disease treatment is recommended over traditional surgery. The present investigation compares endovenous laser ablation (EVLA) with radiofrequency (RF) for segmental endovenous sapheno–femoral junction ablation.

Methods

This is a retrospective study in which 79 patients underwent a 6 cm great saphenous vein ablation by RF or by EVLA. Primary outcome was occlusion rate. Secondary outcomes included Venous Clinical Severity Score (VCSS), Aberdeen Varicose Vein Questionnaire (AVVQ) score, peri-procedural pain, aesthetic satisfaction.

Results

At 12 ± 1 months recanalization of shrunk tract was recorded in 5/85 (5.8%) cases (2 RF, 3 EVLA) [OR: 1.6; 95%CI: 0.2–10.4; P = 0.6689]. Two cases (1/44 RF group and 1/38 EVLA group) also showed reflux recurrence [OR: 1.0; 95%CI: 0.06–17.8; P = 1.0000]. No significant differences between groups were found in AVVQ, VCSS, peri-procedural pain, or aesthetic satisfaction.

Conclusion

Saphenous sparing is feasible and effective by means of both EVLA and RF, representing a possible alternative to surgery.
Performing ‘the authoritative account’: How the BBC’s Horizon produces epistemic authority
Authors: Kantor Brian James
Published: August 2020

Viewers have often looked upon the BBC’s science documentary strand, Horizon, as an authoritative source for scientific knowledge. Through interviews with the series’ producers, this article examines the practices its producers perform to buttress their authority and generate the view that this show is itself a producer of knowledge, even while it is also televising and mediating science. Of particular note are references to science fiction to police boundaries between science and pseudoscience, and the use of original experimental trials to generate witnesses. These position Horizon as at least a node in the network of scientific knowledge production.
Using Close-Range Photogrammetry to Measure Pavement Texture Characteristics and Predict Pavement Friction
Authors: Al-Assi Mohammad , Kassem Emad , Nielsen Richard
Published: August 2020

Pavement friction measurements are collected and used to assess the functional characteristics of pavements to ensure an adequate level of friction. There are several factors that affect pavement friction including the properties of the tire rubber materials and pavement surface texture characteristics. This study utilized the close-range photogrammetry (CRP) technique to measure the pavement macrotexture and microtexture. Texture parameters were calculated from the collected and analyzed images of the pavement surface. The results of the CRP texture measurements were compared with typical measurement methods. The CRP texture measurements had excellent correlation with the measurement methods used in this study; however, the CRP offers a simple and accurate, yet inexpensive, alternative to the current methods used to measure surface macrotexture and microtexture. In addition, the CRP texture parameters were incorporated in the Persson friction model to predict skid friction as a function of rubber properties. The results demonstrated an excellent correlation between measured and predicted friction. This study greatly simplified the texture parameter calculations needed in the Persson friction model with good accuracy.
Mixed Marriages in Late Nineteenth to Early Twentieth Century: Comparing Russia and Norway
Authors: Glavatskaya Elena , Thorvaldsen Gunnar , Borovik Iulia , Zabolotnykh Elizaveta
Published: August 2020

This article compares interethnic and interreligious marriages in Russia and Norway during the decades around 1900. State churches dominated religious life in both countries with over 90 percent of the population but both were losing influence during the period we focus on—rapidly in Russia after the 1917 Revolution. The part on Norway employs nominative and aggregate census material which from 1865 asked questions about religious affiliation, while the Russian case study utilizes the database of church microdata being built for Ekaterinburg—a railway hub and an industrial city in the Middle Urals, in Asia—in addition to census aggregates. Our main conclusion is that religion was a stronger regulator of intermarriage than ethnicity. Religious intermarriage was unusual in Ekaterinburg, even if official regulations were softened by the State over time—the exception is during World War I, when there was a deficit of young, Russian men at home and influx of refugees and Austro-Hungarian Prisoners of War (mostly Catholics and Lutherans). The situation was also affected by the 1917 Revolution creating equal rights for all religious denominations. The relatively few religious intermarriages in Norway were mostly between members of different Protestant congregations—nonmembers being the only group who often outmarried. We conclude that representatives of ethnic minorities and new religions seldom outmarry when religion was important for maintaining their identity.
Rise Up: Understanding Youth Social Entrepreneurs and Their Ecosystems
Authors: Bublitz Melissa G. , Chaplin Lan Nguyen , Peracchio Laura A. , Cermin Ashley Deutsch , Dida Mentor , Escalas Jennifer Edson , Eilert Meike , Gloukhovtsev Alexei , Miller Elizabeth G.
Published: August 2020

This research focuses on youth social entrepreneurs who are leading ventures that address pressing societal problems including climate change, gun reform, and social justice. It answers Journal of Public Policy & Marketing’s call for more research in marketing on social entrepreneurship. Consistent with the mission of Transformative Consumer Research to enhance individual and societal well-being, this research explores how the dynamic ecosystem of youth social entrepreneurs empowers them to rise up to transform people, communities, and the future for the better. The authors partnered with 20 established youth social entrepreneurs who have founded social impact initiatives as well as two organizations that support youth social entrepreneurs, Ashoka and Future Coalition, to develop a framework for understanding the ecosystem that encourages youth social entrepreneurs to enhance people’s well-being and make the world a better place. This framework integrates the experiences of these youth social entrepreneur partners and extant literature in marketing and related disciplines to provide guidance that can help researchers, policy makers, educators, and parents design an environment to support the success of youth social entrepreneurs.
Ultrathin single and multiple layer electrospun fibrous membranes of polycaprolactone and polysaccharides
Authors: Rodríguez-Sánchez Ingrid Juliet , Vergara-Villa Natalia Fernanda , Clavijo-Grimaldo Dianney , Fuenmayor Carlos Alberto , Zuluaga-Domínguez Carlos Mario
Published: August 2020

Electrospinning was used to produce fibrous membranes, in single and multiple layers, from poly(ε-caprolactone), pullulan, and from mixtures of poly(ε-caprolactone) with potato modified starch and β-glucan. It was possible to obtain single-layer membranes from solutions of pullulan in water, poly(ε-caprolactone) in chloroform, and from mixtures of poly(ε-caprolactone)/β-glucan and poly(ε-caprolactone)/potato modified starch in chloroform. Scanning electron microscopy images showed the formation of ultrathin homogeneous fibers from electrospun poly(ε-caprolactone) and pullulan, whereas the fibers obtained from mixtures of poly(ε-caprolactone)/ β -glucan and poly(ε-caprolactone)/potato modified starch had different sizes and morphologies, as well as irregular microstructures, characterized by the presence of beads. Contact angle analyses showed that pullulan membranes were extremely hydrophilic, while poly(ε-caprolactone) membranes were predominantly hydrophobic. Subsequently, poly(ε-caprolactone)-pullulan-poly(ε-caprolactone) multilayer membranes, with intermediate wettability, were prepared by successive electrospinning steps. Infrared spectroscopy and calorimetric analyses showed the presence of both polymers and the absence of changes in their structure and stability due to electrospinning, indicating adequate compatibility between the two polymers. We foresee that the polyester-polysaccharide multilayer membrane might be used as a biodegradable vehicle for active agents with different hydrophobicity, with applications as food packaging and biocompatible scaffold materials.
Investigating the Welfare Deservingness of Single Mothers: Public Image and Deservingness Perceptions in Hungary
Authors: Herke Boglárka
Published: August 2020

The literature on single mothers’ welfare deservingness is dominated by analyses carried out in Anglo-Saxon countries. Those analyses tend to point to an undeserving public image of single mothers. This negative perception is often explained by the identity gap between middle-class voters and poor single mothers, which is partly fuelled by conservative family values in mainstream society. This study investigates the issue in Hungary, where the government has strongly promoted traditional family ideals and significantly increased the support for affluent two-parent families in the past decade. First, the study explores the public image of single mothers based on open-ended and closed-ended survey questions. Second, it measures the perceived deservingness of the group based on five criteria (control, attitude, reciprocity, identity, and need) (van Oorschot 2000) by using the same open-ended question data and a series of other survey data. The results show that single mothers have a coherent deserving public image in Hungary: they have a hard life, do everything to make a living for their family, and lack appropriate financial and emotional support. Results, however, also show that public attitudes are in line with the government’s conservative family policy, and there is, indeed, an identity gap between single-mother families and the public. Nevertheless, this identity gap is not enough to generate negative welfare attitudes towards single mothers because they are perceived as deserving regarding the other four deservingness criteria.
Agency, Eating Disorders, and an Interview With Olympic Champion Jessie Diggins
Authors: Terry Paul E.
Published: August 2020

Eating disorders present health promotion professionals and health care providers with the most complex cultural, social, genetic, emotional, and behavioral syndromes of our time. Whether from the acute threat of bulimia or the chronic disease risk of overeating, the lives of families, and the health of workplaces and communities are affected alongside those struggling with addiction. Social learning theory shows the powerful impact those with “admired status” can have on improving social and behavioral practices. In this interview with Olympian Jessie Diggins, and in this review of her book “Brave Enough,” readers will find that Diggins checks all the boxes that renowned scholar Albert Bandura had in mind as instrumental for adopting modeled behaviors.
On effect of chemical-assisted mechanical blending of barium titanate and graphene in PVDF for 3D printing applications
Authors: Sharma Ravinder , Singh Rupinder , Batish Ajay
Published: August 2020

The polyvinylidene difluoride + barium titanate (BaTiO3) +graphene composite (PBGC) is one of the widely explored thermoplastic matrix due to its 4D capabilities. The number of studies has been reported on the process parameters of twin-screw extruder (TSE) setup (as mechanical blending technique) for the development of PBGC in 3D printing applications. But, hitherto, little has been reported on chemical-assisted mechanical blending (CAMB) as solution mixing and melt mixing technique combination for preparation of PBGC. In this work, for preparation of PBGC feedstock filaments, CAMB has been used. Also, the effect of process parameters of TSE on the mechanical, dimensional, morphological, and thermal properties of prepared filament of PBGC have been explored followed by 3D printing. Further, a comparative study has been reported for the properties of prepared filaments with mechanically blended composites. Similarly, the mechanical properties of 3D printed parts of chemically and mechanically blended composites have been compared. The results of tensile testing for CAMB of PBGC show that the filament prepared with 15% BaTiO3 is having maximum peak strength 43.00 MPa and break strength 38.73 MPa. The optical microphotographs of the extruded filaments revealed that the samples prepared at 180°C extruder temperature and 60 r/min screw speed have minimum porosity, as compared to filaments prepared at high extruder temperature. Further, the results of the comparative study revealed that the filaments of CAMB composites show better mechanical properties as compared to the filaments of mechanically mixed composites. However, the dimensional properties were almost similar in both cases. It was also found that the CAMB composites have better properties at low processing temperature, whereas mechanically blended composites show better results at a higher temperature. While comparing 3D printed parts, tensile strength of specimens fabricated from CAMB was more than the mechanically blended PBGC.
Using simulation to develop business strategy skills of entrepreneurs - Some reflections on a pilot
Authors: Barnaby Julie , Devins David , Beech Nicholas
Published: August 2020

It is recognized that the value of entrepreneurship education and the recruitment of practising entrepreneurs for such learning programmes can be problematic. This raises an important and challenging issue for universities when they are increasingly being asked to develop the leadership and management capabilities of entrepreneurs. In this account of practice, the authors explore the role for business simulation in the development of existing entrepreneurs’ and small business leaders’ strategic decision-making skills. The article describes and reflects on a pilot business simulation course, considering the challenges in the planning, the engagement of entrepreneurs and the delivery of the programme. It provides insights into the value of introducing this form of learning experience and exposes the significant challenges associated with engaging small business leaders.
Design and analysis of automotive lightweight materials suspension based on finite element analysis
Authors: Ciampaglia Alberto , Santini A , Belingardi G
Published: August 2020

In this paper, an integrated method for the design of suspension components with lightweight materials is proposed. Starting from the well-established design flow for chassis components, the paper analyse the manufacturing and design aspect which are mutual dependent in composite structures, providing technical guidance. The proposed design methodology is applied to an innovative suspension archetype patented by Magneti Marelli, F.L.E.C.S. (Flexible Link Elevated Compliance Suspension). First, an analysis of available lightweight material is carried out to define which one best fits the design requirements in terms of density, stiffness, cost and manufacturability. Second, structural simulations, based on finite element analysis, are performed to investigate the influence of the thickness and material on the elasto-kinematic performance of the suspension. According to the stress distribution, an optimization of the shape and the stacking sequence of the component is performed. The results show that 8.5 mm carbon fibre reinforced epoxy is the best solution for the blades, and 5 mm aluminium alloy for the reinforcement tube wall thickness. Third, with respect to the final design, an adhesive interface is analysed and designed, using the Goland-Reissner model.
Beyond the asylum and before the ‘care in the community’ model: exploring an overlooked early NHS mental health facility
Authors: Malathouni Christina
Published: August 2020

This article discusses the Admission and Treatment Unit at Fair Mile Hospital, in Cholsey, near Wallingford, Berkshire (now Oxfordshire). This was the first new hospital to be completed in England following the launch of the National Health Service. The building was designed by Powell and Moya, one of the most important post-war English architectural practices, and was completed in 1956, but demolished in 2003. The article relates the commission of the building to landmark policy changes and argues for its historic significance in the context of the NHS and of the evolution of mental health care models and policies. It also argues for the need for further study of those early NHS facilities in view of current developments in mental health provision.
Influence of endwall slotted injection on performance and flow physics in a compressor cascade
Authors: Cao Zhiyuan , Song Cheng , Liu Bo , Gao Limin
Published: August 2020

Air injection is an effectively methodology to suppress flow separation and to improve blade loading of airfoils and compressors. In order to remove corner separations in a cascade, investigation of endwall slotted injection was carried out numerically in this study. Based on endwall slot schemes of other flow control methods, six different endwall slots were designed, aiming at revealing the axial location effect and pitchwise location effect. For each endwall slot, numerical simulations were performed with six different injection directions to uncover the injection direction effect. Results showed that endwall slotted injection can effectively remove the corner separation. The overall loss coefficient and endwall loss coefficient of the cascade were reduced by 10.3% and 36.8% at most, respectively. Injection from leading edge and mid-chord can reduce endwall loss; however, the optimal axial location of endwall slot is near the trailing edge, where the corner separation is located. Different with other flow control methods, in general, the optimal pitchwise location of endwall slot is not close to suction surface but 0.16 pitch away from it. Injection near the suction surface is more sensitive to injection direction compared with injection at 0.16 pitch away from suction surface. Injection with velocity components both downstream and toward suction surface promises optimal control effect on corner separation. However, at mid-span, trailing edge separation is deteriorated and the flow turning angle is reduced, the flow mechanism being that the low-momentum fluid migrates along spanwise.
Methylphenidate causes cytotoxicity on photoreceptor cells via autophagy
Authors: Kong N , Bao Y , Zhao H , Kang X , Tai X , Shen Y
Published: August 2020

Methylphenidate (MPH) is used as the first-line treatment for attention-deficit hyperactivity disorder. However, there are concerns that this treatment may be associated with increased risk of retinal damage. This study was to investigate cytotoxicity of MPH on photoreceptor cells and explore its underlying mechanisms. MPH-caused cell toxicity was established in 661 W cells. Cytotoxicity was evaluated by 3-(4,5-dimethylthiazol)-2,5-diphenyltetrazolium-bromid and lactate dehydrogenase assays. Oxidative stress was measured by the markers: glutathione (GSH) reductase, catalase, and superoxide dismutase activities as well as GSH, reactive oxygen species, and malondialdehyde levels. Gene and protein expression was detected by real-time polymerase chain reaction (PCR) and western blot, respectively. Results showed that MPH decreased 661 W cell viability, increased caspase-3/9 activities, and induced oxidative stress. Furthermore, MPH treatment increased messenger RNA (mRNA) expression of Beclin-1 and microtubule-associated protein 1A/1B-light chain 3B (LC3B) protein expression in 661 W cells, suggesting autophagy was induced. MPH treatment also upregulated p-JAK1/p-STAT1 protein expression. These data demonstrated that MPH could increase oxidative stress in photoreceptor cells to cause cell toxicity via autophagy, providing the scientific rationale for the photoreceptor cell damage caused by the MPH administration.
Claudin-7 Inhibits Proliferation and Metastasis in Salivary Adenoid Cystic Carcinoma Through Wnt/β-Catenin Signaling
Authors: Ji Huan , Ding Xu , Zhang Wei , Zheng Yang , Du Hongming , Zheng Yangyu , Song Haiyang , Li Meng , Jiang Yue , Xie Jiaxiang , Wu Ming , Jiao Pengfei , Wang Zeyu , Wu Heming , Zhong Yi
Published: August 2020

The aim of this study was to investigate claudin-7 (CLDN7) expression in salivary adenoid cystic carcinoma (SACC) and its function in SACC cells. We determined CLDN7 expression in SACC tumors via immunohistochemistry and western blotting and evaluated the association between CLDN7 expression and clinicopathologic variables. Besides this, we constructed a stably transfected CLDN7 knockdown SACC-LM cell line via RNAi and assessed its biological behavior changes (cell viability, migration, and invasion). The correlation between CLDN7 and epithelial-mesenchymal transition (EMT) was analyzed. Additionally, a subcutaneous tumor formation model was used to assess SACC-LM cells tumorigenicity after the CLDN7 knockdown. In the present study, we found the CLDN7 expression of tumor group was lower than that in normal salivary glands and was significantly correlated with lymph node metastasis, recurrence, and gender. CLDN7 knockdown could add the proliferation and metastasis ability of SACC by regulating EMT through Wnt/β-catenin signaling pathway. In addition, CLDN7 knockdown in SACC promoted tumor growth in nude mice. CLDN7 inhibits cell proliferation and metastasis by inactivating the Wnt/β-catenin signaling in SACC. Thus, CLDN7 expression might be a useful marker to identify the potential for progression in SACC.
The attitudes of collegiate coaches toward gay and lesbian athletes in Taiwan, Hong Kong, and China
Authors: Tseng Yu-hsien , Sum Raymond Kim-Wai
Published: August 2020

This study focused on the attitudes of 14 collegiate coaches toward gay and lesbian athletes in Taiwan, Hong Kong, and China and the experience these coaches have had with such athletes. Interview results revealed that different levels of progress in the advocacy for gender equity education and/or sexual minority topics had affected the coaches’ attitudes toward gay and lesbian student athletes. However, with increased contact, the coaches became more inclusive and tolerant toward student athletes with different sexual orientations. Moreover, coaches perceived that their primary role involved enhancing athletic performance and meeting the needs of student athletes instead of offering different training sessions and opportunities for competition. Future studies should focus on specific sport communities and include student athletes and coaches with diverse sexual orientations. College administrators should offer relevant educational programs for coaches to create dialogue and nurture a positive environment for athletes with diverse sexual orientations.
Using participatory methods to evaluate the impacts of an early intervention programme on children and young people (CYP)
Authors: Evans-Locke Kylie , Hsu Ching-I
Published: August 2020

The child’s voice is often excluded in child and family service programme evaluations, with research traditionally favouring the views of parents, carers and other adults. Evaluations that do not provide adequate opportunities for children and young people (CYP) to be involved potentially risk misunderstanding wider programme impacts and minimising CYP-specific outcomes. CareSouth has piloted an evaluation utilising body-mapping to collect programme feedback from CYP to provide valuable insights into perceived outcomes in areas of social connection, cognitive skills and development of positive personal identity. This article will share insights and lessons CareSouth encountered during the evaluation, the methods used to ensure ethical evaluation and the lessons for other child and family service practitioners looking to extend meaningful consultation with CYP to ensure greater understanding of holistic programme impacts.
Comparison of 2 ELISAs for detecting exposure to Brucella ovis
Authors: Elderbrook Molly J. , Schumaker Brant A. , Ueti Massaro W. , Bastos de Almeida Meila , Vieira Thallitha S. W. J. , Vieira Rafael F. C. , Sondgeroth Kerry S.
Published: August 2020

Control of Brucella ovis infection in sheep flocks in the United States depends on early detection of B. ovis antibodies via serologic testing. We used 2,276 sheep sera and various cutoff values to compare seroprevalence and agreement between 2 ELISAs: the National Veterinary Services Laboratories (NVSL) B. ovis indirect ELISA and the IDEXX B. ovis ELISA kit. A subset of 295 sera was used to compare agreement and evaluate relative sensitivity and specificity of the 2 ELISAs with an agar gel immunodiffusion (AGID) test kit. There was no significant difference in B. ovis seroprevalence between the ELISAs; however, there was poor agreement between them. When the AGID test was used as the reference test, the IDEXX ELISA with a moderate cutoff value (S/P ratio = 45%) had the highest relative sensitivity of 38.1% and specificity of 92.0%. The NVSL ELISA with a lax cutoff value (S/P ratio = 0.75) had relative sensitivity of 19.1% and specificity of 94.6%. Receiver operating characteristic analysis revealed that optimal cutoff values for the NVSL and IDEXX ELISAs were 0.091 and 16.5%, respectively. This results in sensitivity and specificity of 85.7% and 31.8% for the NVSL ELISA, and sensitivity and specificity of 81.0% and 53.6% for the IDEXX ELISA, respectively.
Youth and Pet Survivors: Exploring the Experiences of Pediatric Oncology and Bone Marrow Transplant Patients in a Virtual Animal-Assisted Therapy Pen Pal Program
Authors: Gillespie Anne Ingalls , Neu Madalynn
Published: August 2020

Introduction: YAPS™ (Youth and Pet Survivors™) is a form of virtual animal-assisted therapy (AAT), a pen pal program designed for children and adolescents with cancer and/or having a bone marrow transplant (BMT) to engage in virtual visits with a dog or a cat (who has also been treated for cancer or serious medical illness) through letter writing and pictures. The purpose of this qualitative descriptive study was to explore the experiences of YAPS participants over time and to explore how virtual AAT may be an additional or alternative intervention to the traditional form of AAT, which involves live visits with animals, primarily dogs. Method: Open-ended, face-to-face interviews were conducted throughout the participants’ involvement with their animal pen pal. Interviews were digitally recorded. Data were analyzed using a content analysis method. Results: Fifteen children and adolescents, aged 7 to 16 years, participated. Three main themes and five subthemes were found, including connection, shared experience, and friendship. Themes suggested that a virtual AAT letter writing program can provide a source of fun and a way to process the cancer experience with a dog or cat pen pal who has also faced cancer or serious medical treatment. Discussion: Interventions that promote well-being for pediatric oncology and BMT patients are needed, and virtual AAT seems to be one such intervention suited for those who have an affinity for animals and enjoy letter writing. The findings of this study also presented an exciting and intriguing gap for further research in virtual AAT.
Tuning the hygro-mechanical response of paper-based systems using glycerol
Authors: Cueva-Perez Isaias , Osornio-Rios Roque Alfredo , Dominguez-Gonzalez Aurelio , Stiharu Ion , Perez-Cruz Angel
Published: August 2020

In recent years, the need for portable, low-cost, and eco-friendly devices for testing and monitoring has arisen. Paper-based devices have emerged as a response to these needs due to the properties induced by capillarity, flexibility, disposability, and biodegradability. In this work, the authors explored the possibility of tuning the hygro-mechanical response of paper-based cantilever beams using glycerol. A lumped-parameter model with non-linear stiffness is used to describe the dynamic response of the beams using three parameters. An experimental method based on resonance frequency tests is used to study the influence of glycerol on the dynamic response of four different beam configurations. The obtained results demonstrate that the resonance frequency of paper-based mechanical systems can be easily tuned by the imbibition of a glycerol–water solution. This study could lead to the development of tunable paper-based mechanical systems for specific applications such as energy harvesters and hygro-mechanical-based sensors.
Thyroid Adenoma of Probable Ultimobranchial Body Origin: A Case Report
Authors: Yuen K. K. W. , Chan A. N. H. , Chan J. K. C. , Cheuk W.
Published: August 2020

Solid cell nests are generally believed to represent remnants of the ultimobranchial body, which can be found in the normal thyroid gland, occasionally associated with other branchial pouch remnants such as salivary gland, cartilage, and adipose tissue. We describe the case of a 44-year-old man incidentally found to have a large tumor in the left lobe of the thyroid. The tumor was a circumscribed growth consisting of distinctly lobulated proliferation of solid to cystic epidermoid cell nests and thyroid follicles in a fibromatous stroma, which merged into abundant adipose tissue and focally myxoid matrix. The solid epidermoid cell nests resembled solid cell nests and exhibited a p63+, GATA3+, galectin-3+, TTF1−, PAX8−, thyroglobulin− phenotypes, while the follicles were p63−, GATA3−, galectin-3−, TTF1+, PAX8+, and thyroglobulin+. RAS mutations were not found. This thyroid tumor may represent a hitherto undescribed “ultimobranchial body adenoma” in human.
Renin-Angiotensin System Blockade and Mortality in Patients With Hypertension and COVID-19 Infection
Authors: Salah Husam M. , Calcaterra Guisseppe , Mehta Jawahar L.
Published: August 2020

To determine the effect renin-angiotensin system blockers on the outcome in patients with hypertension and concurrent COVID-19 infection, we searched PubMed, the Cochrane Library, and Google Scholar for relevant articles. Twelve studies with a total of 16,101 patients met the inclusion criteria. The mortality rate among the users of angiotensin converting enzyme inhibitors or angiotensin receptor blockers was 12.15% and in non-users it was 14.56% (risk ratio 0.70, 95% CI [0.53-0.91], P < 0.007). There was no difference in the risk of death between the use of angiotensin converting enzyme inhibitors and angiotensin receptor blockers (risk ratio 1.09, 95% CI [0.90 -1.32]). We conclude that the use of angiotensin converting enzyme inhibitors and angiotensin receptor blockers improves mortality in patients with hypertension and concurrent COVID-19 infection, without a significant difference between ACEIs and ARBs in this population.
The Connection Between Mind Wandering, ADHD, and Level of Performance on an Attention Task
Authors: Alali-Morlevy Klodin , Goldfarb Liat
Published: August 2020

Background: ADHD is related to increased mind wandering (MW). However, it is not clear whether this is restricted by the methods used to measure MW in those studies. Moreover, it is not certain whether MW is an independent characteristic of people with ADHD or only due to their poor performance level in the primary task (the task from which attention wanders). Method: Participants with ADHD were compared to two control groups: high performers and low performers in the primary task who had a similar performance level to the ADHD group. Results: The ADHD group had greater MW than the two control groups, while no difference in MW was found between the two control groups. Conclusion: Increased MW is an independent characteristic of ADHD. This was further discussed within the context of different theories regarding ADHD and MW.