bluuebunny/crossref_metadata_2025 huggingface dataset:
Anterior Chamber Iris-Fixated Phakic Intraocular Lens Implantation for Treatment of High Anisometropia in Children: Long-term Results
Authors: Griščíková Lenka , Autrata Rudolf , Krejčířová Inka , Alió Jorge L. , Žajdlíková Barbora , Tomčíková Dana , Hložánek Martin
Published: August 2022

Purpose:

To evaluate the long-term efficacy of anterior chamber iris-fixated phakic intraocular lens (PIOL) implantation in the treatment of high myopic (> −9.00 diopters [D]) or hyperopic (> +6.00 D) anisometropia in children with intolerance to spectacles or contact lenses.

Methods:

A total of 58 children with anisometropic myopia (range: −9.25 to −18.50 diopters [D]) and 13 children with anisometropic hyperopia (range: +6.00 to +8.50 D) underwent unilateral iris-claw PIOL implantation from 2008 to 2018. The mean age was 6.7 years. The mean follow-up was 38.5 months. Target refraction was emmetropia.

Results:

The cycloplegic refraction (mean spherical equivalent) improved from −12.47 D (range: −9.25 to −18.50 D) to −0.73 D (range: +0.75 to −1.50 D) in myopic eyes and reduced from +7.15 D (range: +6.00 to +8.50 D) to +0.94 D (range: −0.50 to + 1.75 D) in hyperopic eyes. Eighty-four percent of eyes were corrected to within ±1.00 D of emmetropia. The mean uncorrected distance visual acuity (UDVA) improved from 1.74 ± 0.36 to 0.45 ± 0.28 logarithm of the minimum angle of resolution (logMAR) (
P
= .0014). The mean corrected distance visual acuity (CDVA) changed from 0.68 ± 0.32 to 0.27 ± 0.15 logMAR (
P
= .02179). The safety index was 2.18 and the efficacy index was 1.51. The mean preoperative endothelial cell count of 2,874.7 cells/mm
2
changed to 2,685.3 cells/mm
2
at 2 to 6 years postoperatively. Binocular vision quality was improved in 55 patients. No patient had serious complications or lost any Snellen lines of CDVA.

Conclusions:

Iris-fixated PIOL implantation is an effective and safe method in the treatment of high anisome-tropic myopia and hyperopia and amblyopia in pediatric patients who are noncompliant with spectacles or contact lenses.

[
J Pediatr Ophthalmol Strabismus
. 2023;60(3):203–209.]
The Effect of Social Determinants of Health on Telemedicine Access During the COVID-19 Pandemic
Authors: Romain Carmelle V. , Trinidad Stephen , Kotagal Meera
Published: August 2022

Social determinants of health contribute to inequalities in access to care and inferior outcomes in pediatric populations. Before the coronavirus disease 2019 (COVID-19) pandemic, telemedicine was shown to be an effective tool to bridge the gap between health care providers and rural or underserved populations. The pandemic has rapidly changed the current landscape of health care. Telemedicine has played a critical role in health care delivery between providers and patients because of the need for social distancing. That being said, it has become apparent that SDOH have affected access to telemedicine for communities that already suffer from inequities in health care access. Solutions directed toward addressing issues such as lack of broadband access, digital literacy and language barriers, and obstacles within the health care system are crucial to ensure telemedicine access is equitable for all patients and does not contribute toward worsening health care disparities.

[
Pediatr Ann
. 2022;51(8):e311–e315.]
Bojevniška eksistenca v delih Ernsta Jüngerja in Stanislava Krakova
Authors: Koprivica Časlav D.
Published: August 2022

Prispevek predstavlja fenomenološko razlago bojne situacije oziroma bojevniške eksistence na podlagi esejistične literature Ernsta Jüngerja in vojne proze Stanislava Krakova, dveh izjemnih junakov in prič prve svetovne vojne. Razlaga temelji na motivu situacije, ki ga tu uporabljamo v skladu s Heideggerjevim konceptualnim posegom v delu Ontologija – hermenevtika faktičnosti. Razprava izhaja iz uvida, da je pojem situacije splošna osnova dojemanja vsakršnega konkretnega življenja, paradigma situativnosti pa naj bi igrala odločilno vlogo v filozofiji eksistence, se pravi v samorazumevanju poznomodernega človeka. Ta uvid je predpostavka poglobljene razgrnitve vojaške situacije in njenega pomena za refleksijo o človeškem položaju v sodobnem svetu. Razmišljanja ob Jüngerjevi esejistiki in Krakovovi avtobiografski prozi lahko pokažejo, da je bila prav rovovska eksistenca na frontah prve svetovne vojne merodajna tako za zlom kulture, ki se je zgodil pred izbruhom vojne, kakor za obdobje po versajski pogodbi in »miru«, ki je neposredno sledil.
Comparative Analysis of the Mind Style: Child Narrators in Mark Haddon’s The Curious Incident of the Dog in the Night-Time and Ismail Kadare’s Chronicle in Stone
Authors: Ibishi Ardita , Tahiri Lindita
Published: August 2022

This study compares the stylistic markers of the thinking style of the child narrators in The Curious Incident of the Dog in the Night-Time (2003) by British writer Mark Haddon and Chronicle in Stone (1971) by Albanian writer Ismail Kadare. The paper analyzes the language of the narrators to identify the foregrounded linguistic elements in the narrative and consequently their reliability and impact on the reader. The linguistic features that characterize the child narrators of these novels are considered as features of their thinking style that indicate the limitations of their age and create the effect of unreliability. The analysis of the narrators’ stylistic features points to the foregrounded patterns that differ slightly in both narrators and are demonstrated at different linguistic levels such as lexical choices, coordinated syntactic patterns, juxtapositions of literal and figurative meanings, and the inclusion of other elements that mark the distinction of their idiosyncrasies and social background. By reflecting the child’s genuine naiveté, the narrative device of unreliability evokes empathy and enhances the reader’s interpretive power.
The Rhetoric of Imagism in the Cinepoetry of Jean Cocteau and Abbās Kīyārustamī: A Comparative Study
Authors: Mosavat Mohamad , Mohajeri Faezeh
Published: August 2022

This article examines the shared Imagistic principles of two poet-filmmakers in the experimental genre of cinepoetry. On the one hand, Jean Cocteau, the French poet-turned-filmmaker, epitomizes the Imagistic experimentations of a French filmmaker with the narrative framework of poetry to create a “page-based” movie. On the other hand, Abbās Kīyārustamī, the Iranian filmmaker-turned-poet, typifies the cinematic aesthetic of modern Persian poetry to offer visual images that rely entirely on the creative engagement of the reader. The rhetoric of Imagism, that short-lived modernist movement of the early twentieth century, is what these poet-filmmakers similarly employ in their cinepoetic study cases, namely Tempest of Stars (1997) by Cocteau and A Wolf Lying in Wait (2005) by Kīyārustamī. Following a comparative approach to their common Imagistic foundations such as economical wording and phrasing, cinematic adaptation of visual imagery, rigor and clarity of vision, the poetic prerogative of subject matter, the avoidance of vague and ambiguous descriptions, and the writerly approach to the rhetoric of the poem, this article proves that Cocteau and Kīyārustamī are respectively the epitomes of Imagistic cinepoetry in French and Persian literature.
Green Management Orientation in the Supply Chain of the Apparel Industry
Authors: Weeratunge R. A. D. Dillanjani , Herath Renuka , Weligamage Susima
Published: August 2022

The green management orientation practices in supply chain are examined in terms of how green practices improve the supply chain, what is the current nature of supply chain and why green orientation is poor in supply chain. A multi-case study approach is employed based on seven apparel manufactures in Sri Lanka. Cross-case analysis highlights the water, energy, earth conservative practices followed by apparel companies. A key factor identified that has not been highlighted in the literature is green management orientation initiatives in the supply chain which intensifies the development of environmental sustainability. There is a knowledge gap in the existing supply chain literature, especially on sustainable practices followed by manufacturing industries. This study adds to the literature on green supply chain management by identifying the effects of Green Management Orientation (GMO) practices. The concept of green initiatives for apparel manufacturers is discussed. The factors that contribute to green sustainability development are zero land filling, rain water harvesting, sludge drying, reduce CO2 omission and make polyester yarn from recycling pet bottles. Further, three main themes are developed on what are factors affect to the green management orientation involvement in the supply chain. This paper responds recent calls for greater scrutiny of why and how firms decouple with green practices and supports the development of the literature specially on environment sustainability. The findings have implications for the diffusion of green practices into supply chain. Used the purposive sampling method for data collection.
Influence of Customer Generated e-WOM on Purchase Intention of Cosmetic Products in Sri Lanka
Authors: Fathima Nushra Mohamed Najeem , Mubarak Kaldeen Mohamed
Published: August 2022

The main purpose of this study is to investigate the influence of eWOM on consumer purchase intention. Moreover, this study examines the extent to which relationship exists between eWOM credibility, eWOM review quantity, eWOM perceived usefulness and consumer purchase intention in cosmetic products in Sri Lanka. The primary data was collected through an online survey with the help of a standardized questionnaire from 400 cosmetic product consumers in Sri Lanka. The items of the questionnaire extracted from previous research and altered them as per study requirement. The result of this research implies that eWOM Credibility, eWOM Review Quantity and eWOM Perceived Usefulness has significant impact on Purchase Intention. The element that has the highest impact is eWOM perceived usefulness which entirely contributes to the effectiveness of eWOM while eWOM credibility and eWOM review quantity have less impact. These three elements thoroughly perform different roles in influencing consumer purchase intention. This research is limiting only three main determinants such as eWOM credibility, eWOM review quantity and eWOM perceived usefulness which determine the purchase intention. There may be other factors also which are affecting that can be considered for further research. Companies could use tactics to encourage potential customers to thoroughly read eWOM provided in social media or consumer reviews. This study provides valuable insights into the eWOM which affects consumer purchase intention.
Review of Mergers & Acquisition Cases in Sri Lanka
Authors: Lye Ramzeena Morseth
Published: August 2022

Mergers & Acquisitions (M&A) are strategic growth tools used by organizations aiming for market dominance and sustainable growth in shareholder wealth. While M&A sound impressive they involve many complexities, conundrums and risks (Angwin, 2001; Algama, 2020) requiring a great deal of thinking, effort and resources to get right. Despite the commonality of M&A in developed as well as emerging markets a good majority of them fail (Hitt, 2012) and there doesn’t seem to be a thorough understanding of why they fail (Cartwright and Schoenberg, 2006). This article is a brief review of several noteworthy M&A executed in Sri Lanka in the recent history between Dialog Axiata & Wow.lk, Dialog Axiata & H-One, Mobitel & E-Channeling, Hutch Lanka & Etisalat Sri Lanka, ACL Cables & Kelani Cables, Gamma Pizzakraft & Keells Restaurants (Pizza Hut operation in Sri Lanka), Softlogic Holdings & Odel/Cotton Collection, SS Equity Holdings & RIL Property PLC (BreadTalk operation in Sri Lanka). The article attempts to understand the likely business objectives behind these strategic moves and if the expected results have materialized. Empirical evidence suggests that a vast majority of M&A fail to deliver the expected results. It is important that business managers evaluate the pros and cons of the M&A route carefully, formulate well defined goals & strong integration plans should they wish to proceed. The analysis was carried out based on already published data using company press releases, information from their websites, other online press articles, existing literature on mergers & acquisitions and authors experience/involvement in two of the cases being discussed and insights from industry insiders.
Effect of Remote Ischemic Conditioning on Heart Rate Responses to Walking in People with Multiple Sclerosis
Authors: Kai Xin Noelle Chung , Nair Krishnan , Chotiyarnwong Chayaporn , Baster Kathleen , Buckley Ellen , Mazza Claudia , Ali Ali , Baig Sheharyar
Published: August 2022

Background:

Remote ischemic conditioning (RIC), exposure of body parts to brief periods of circulatory occlusion and reperfusion, has been shown to improve cardiovascular responses to exercise in healthy individuals but its effects in people with MS are unknown.

Objective:

This study aimed to assess the effect of RIC on heart rate responses to walking in people with MS.

Design:

Double blind randomized controlled trial

Setting:

Multiple sclerosis clinic of tertiary care center teaching hospital in the United Kingdom.

Methods:

Three cycles of RIC were delivered by occluding the upper arm with a blood pressure cuff inflated to a pressure of 30 mmHg above the systolic blood pressure. In the sham group, the blood pressure cuff was inflated to 30 mmHg below diastolic blood pressure. Heart rate responses to the 6-minute walk test (6MWT), the tolerability of RIC using a numerical rating scale for discomfort (0-10), and adverse events were studied.

Results:

Seventy-five participants (RIC -38 and Sham-37) completed the study. RIC was well tolerated. Compared to sham, RIC significantly decreased the rise in heart rate (P = 0.04) and percentage of predicted maximum heart rate (P = 0.016) after the 6MWT.

Conclusion:

RIC was well tolerated and improved the heart rate response to walking in people with MS. Further studies on RIC in the management of MS are needed.
Ischemic Optic Neuropathies
Authors: Patil Ajay D. , Biousse Valerie , Newman Nancy J.
Published: August 2022

Ischemic optic neuropathy (ION) is the term ascribed to optic nerve disease that is the result of a transient or permanent interruption of the blood supply to any portion of the optic nerve. Anterior ischemic optic neuropathy (AION) refers to ischemia of the optic nerve head, whereas posterior ischemic optic neuropathy (PION) indicates ischemia of the posterior optic nerve. IONs are primarily classified as arteritic ION and non-arteritic ION. A subset of ION that occurs around the time of surgery is termed peri-operative ION. These phenomena will be discussed as distinct entities.
Digital anatomical study based on Chinese Visible Human data sets
Authors: Chen Na , Liu Jingjing , Zhang Shaoxiang , Wu Yi
Published: August 2022

Chinese Visible Human (CVH) data sets have been widely used in anatomical teaching and scientific research. Based on true-color, thin-thickness, and high-resolution images which are much more superior than computed tomography, magnetic resonance imaging, and ultrasound, human organs have been segmented and three-dimensional (3D) reconstructed, and the organs have higher accuracy and more detailed information, which makes complex anatomical structures simplified, and makes abstract anatomical structure visualization. Through CVH and their 3D models, researchers got much more anatomical new finding and understanding about human anatomy, which can update anatomical reference books and atlas, and can provide more human morphological information for medical students, surgeons, and anatomists. Here, we will provide a brief summary of the CVH data sets and its applications in teaching and research in recent years.
Application of graph-based features in computer-aided diagnosis for histopathological image classification of gastric cancer
Authors: Zhang Haiqing , Li Chen , Ai Shiliang , Chen Haoyuan , Zheng Yuchao , Li Yixin , Li Xiaoyan , Sun Hongzan , Huang Xinyu , Grzegorzek Marcin
Published: August 2022

Background:

The gold standard for gastric cancer detection is gastric histopathological image analysis, but there are certain drawbacks in the existing histopathological detection and diagnosis.

Method:

In this paper, based on the study of computer-aided diagnosis (CAD) system, graph-based features are applied to gastric cancer histopathology microscopic image analysis, and a classifier is used to classify gastric cancer cells from benign cells. Firstly, image segmentation is performed. After finding the region, cell nuclei are extracted using the k-means method, the minimum spanning tree (MST) is drawn, and graph-based features of the MST are extracted. The graph-based features are then put into the classifier for classification.

Result:

Different segmentation methods are compared in the tissue segmentation stage, among which are Level-Set, Otsu thresholding, watershed, SegNet, U-Net and Trans-U-Net segmentation; Graph-based features, Red, Green, Blue features, Grey-Level Co-occurrence Matrix features, Histograms of Oriented Gradient features and Local Binary Patterns features are compared in the feature extraction stage; Radial Basis Function (RBF) Support Vector Machine (SVM), Linear SVM, Artificial Neural Network, Random Forests, k-NearestNeighbor, VGG16, and Inception-V3 are compared in the classifier stage. It is found that using U-Net to segment tissue areas, then extracting graph-based features, and finally using RBF SVM classifier gives the optimal results with 94.29%.

Conclusion:

This paper focus on a graph-based features microscopic image analysis method for gastric cancer histopathology. The final experimental data shows that our analysis method is better than other methods in classifying histopathological images of gastric cancer.
Educational Intervention and Referral for Early Detection of Endometriosis among Technical Secondary Schools Students
Authors: Abd Elrahim Amany H. , Abdelnaem Safaa A. , Abuzaid Ola N. , Allah Magda F.H.
Published: August 2022

Background

Endometriosis is a long-lasting state in which endometrial-like tissue is found outside the uterus often on the reproductive organs, bowel, and bladder.

Aim

To evaluate the effect of educational intervention and referral for early detection of endometriosis among technical secondary school students.

Patients and methods

A quasi-experimental research design was used to achieve the aim of the study.

Setting

The study was carried out at technical secondary schools for girl students at Minia City.

Sampling

A total of 300 adolescent girls were selected using a cluster sampling technique.

Tools

Four tools were used for data collection: tool 1, sociodemographic data and menstrual history; tool 2, symptoms/risk factors assessment tool for early detection of endometriosis; tool 3, knowledge assessment tool about endometriosis; and tool 4, management practices assessment tool.

Results

The current study revealed that 72.8% of girl students had poor knowledge about endometriosis in pretest, which decreased to 20.3% in posttest. In addition, there were statistically significant improvements among referred girls regarding their management practices related to symptoms suggesting endometriosis in pretest (10.3%) and posttest (77.3%). Furthermore, there were positive correlations between knowledge about endometriosis among studied students and their symptom management practices after implementation of the educational intervention.

Conclusion

Implementation of educational intervention among adolescent girls was effective in early detection and early management of endometriosis and in improving their knowledge and their management practices regarding endometriosis.

Recommendations

More research studies are needed to increase adolescent girls’ awareness regarding endometriosis because there are scant research studies in this field.
Family caregivers of children with cerebral palsy
Authors: Monem Fouad Nawal A. Al , Ali Nadia A.A. , Amen Huda A. Al
Published: August 2022

Background

Cerebral palsy (CP) is a group of permanent movement disorders that appear early in life. So, having a child with disability is a major event that negatively affects families and forces families to evaluate their plans, goals, and relationships in light of restrictions and limitations associated with child disability.

Aim and objectives

The present study aimed to assess the burden and self-efficacy level of family caregivers of children with CP.

Patients and methods

This study was conducted at the National Institute of Neuro Motor Rehabilitation, Embaba, Giza Governorate.

Result

Overall, 72% of family caregivers experience moderate to severe burden and 16% experience mild to moderate burden, whereas 12% experience severe burden. Moreover, 94% of family caregivers can control thinking of how unfair they have to put up with taking care of their children with CP and 90% cannot ask a friend or family member to stay with the children with CP, whereas 88% cannot control their anger or answer their children with CP without raising their voice.

Conclusion

These results suggest caring for a child with CP may put the family caregivers at risk of moderate to severe burden and affect their relationships with other family members or friends in a negative way, and they might feel angry when they are around their relatives.
Effect of Benson’s relaxation therapy on pain and sleep quality among post-cesarean mothers
Authors: Mansour Suzan El-said , Saadoon Om Hashim Mahmoud
Published: August 2022

Aim

The aim of the current study was to evaluate the effect of Benson’s relaxation therapy (BRT) on pain and sleep quality among post-cesarean mothers.

Design

A quasi-experimental design with the pretest and posttest control group design was used.

Setting

This study was conducted at postpartum wards at Mansoura University Hospital, Egypt.

Subjects

The purposive sample consisted of 62 post-cesarean mothers on their first and second postoperative days, who were divided into intervention and control groups of 31 participants each.

Tools

Structured interview schedule, visual analog pain scale to assess pain intensity, and Groningen sleep quality scale to assess sleep quality were used for collecting data.

Results

There was no statistically significant difference between the studied groups concerning their general characteristics. Nevertheless, a statistically significant reduction was found in the mean of post-cesarean pain score for the intervention group compared with the control group by 5.09±0.94 versus 7.03±0.66 on the second day and 2.42±1.09 versus 5.32±0.75 on the third day, respectively. Moreover, the quality of sleep improved on the second and third day postoperatively with highly statistically significant difference, whereas the mean score on the second day was 5.03±3.58 versus 8.87±4.17 compared with 2.26±2.48 versus 6.03±4.13 on the third day, respectively. Furthermore, a positive correlation was found between pain intensity and quality of sleep.

Conclusion

It was evident that BRT is an effective and safe method and have a positive effect in reducing pain intensity and improving quality of sleep among post-cesarean mothers.

Recommendations

Integrating BRT in the protocol of nursing for the care of post-cesarean section mothers.
Relationship between ethical leadership and workaholism among nursing supervisors as perceived by staff nurses
Authors: Mahran Hossam M. , Al-Fattah Magda Abd Al-Hamid Abd , Saleh Nadia M.A.
Published: August 2022

Background

Workaholism develops as a result of working long hours to reach mutually agreed-upon goals by ethical leaders who serve as role models and encourage ethical behavior.

Aim

To examine the relationship between nursing supervisors’ ethical leadership and their workaholism as perceived by staff nurses.

Design

A descriptive correlational research design was adopted to achieve the study.

Setting

The study was conducted at Sohag University Hospital.

Patients

As convenience samples, 25 nursing supervisors and 240 staff nurses were recruited.

Tools

Three tools were used for data collection as follows: demographic data forms and ethical leadership and workaholism analysis questionnaires.

Results

Overall, 53.3% of staff nurses reported leaders with low levels of ethical leadership, whereas 46.7% of them were led by ethical leaders. Moreover, 73.3% of leaders had low levels of workaholism, whereas 26.7% of leaders had high levels of workaholism.

Conclusion

There were statistically significant differences and positive relations between ethical leadership and workaholism among the recruited participants.

Recommendations

Training programs should be conducted to teach nursing supervisors about ethical leadership, as well as the dangers of workaholism and how to prevent them.
Rehabilitation in Coronavirus Disease 2019 Positive Post-Partum Haemolysis, Elevated Liver Enzymes and Low Platelet Count Syndrome
Authors: Pandey Sanjay Kumar , Kumar Deepak , Biswas Anurug , Johnson Renu Anna , Rani Madhulika
Published: August 2022

Haemolysis, elevated liver enzymes and low platelet count (HELLP) syndrome is a rare condition associated with cerebrovascular accidents. It usually happens in the third trimester, although it can also present in the early weeks of pregnancy or the postpartum period. A 24-year-old female presented with 39 weeks of gestation. After 2 days of delivery, she developed generalised convulsions and following that she had burst abdomen with sepsis. She was diagnosed with a case of HELLP syndrome. After that she became coronavirus disease 2019 (COVID-19) positive and was shifted to a COVID-intensive care unit (ICU) where she was provided ventilator support. After 3 months of ICU stay, she was shifted to the rehabilitation unit. In the meantime, she had an episode of stroke with associated quadriparesis, impaired cognition, loss of vision, dysphagia and bladder-bowel involvement. Rehabilitation outcome was partially successful in her case. Post-partum HELLP syndrome associated with COVID-19 can develop severe complications. Medical management combined with goal-oriented customised rehabilitation can lead to a better outcome.
Oxidative stress and the importance of H. pylori eradication in patients with functional dyspepsia
Authors: Ebik Berat , Aslan Nihat , Ekin Nazım , Bacaksiz Ferhat , Arpa Medeni , Neselioglu Salim , Erel Ozcan , Ucmak Feyzullah
Published: August 2022

Background:

To investigage the thiol and disulphide levels in Helicobacter pylori-positive patients with non-ulcer dyspepsia and investigate the change in these levels with eradication therapy.

Methods:

This is a prospective observational study. A total of 320 patients diagnosed with dyspepsia according to Rome IV criteria were included in the study. First, blood samples were drawn from patients to determine their serum thiol and disulphide levels. Endoscopic biopsy was performed on all patients and the biopsy specimens obtained were examined pathologically. Patients positive for H. pylori were administered eradication therapy. Blood samples were drawn from these patients for the second time, and their serum thiol and disulphide levels were measured. The thiol–disulfide levels of the patients who were successful in H. pylori eradication treatment, with those who were not, were compared before and after the treatment.

Results:

The mean plasma disulphide level decreased significantly from 14.0 ± 6.6 to 10.9 ± 5.9 μmol/L in H. pylori-positive patients that responded to the H. pylori eradication treatment (P = 0.033). On the other hand, there was an insignificant increase in the mean serum thiol level (341.4 ± 30.5 vs. 342.6 ± 29.8 μmol/L; P = 0.273) and an insignificant decrease in the mean serum disulphide level (15.2 ± 2.5 vs. 14.8 ± 2.3 μmol/L; P = 0.163) in H. pylori-positive patients that did not respond to the H. pylori eradication treatment.

Conclusion:

The inflammation caused by H. pylori shifted the thiol–disulphide equilibrium in the cell redox system towards the direction of disulphide. The study findings suggest that the restoration of the said hemostatic balance with eradication therapy relieved the organism from oxidative stress.
Effectiveness of the Use of Standardized Vocabularies on Epilepsy Patient Cohort Generation
Authors: Jung Hyesil , Lee Ho-Young , Yoo Sooyoung , Hwang Hee , Baek Hyunyoung
Published: August 2022

Objectives: This study investigated the effectiveness of using standardized vocabularies to generate epilepsy patient cohorts with local medical codes, SNOMED Clinical Terms (SNOMED CT), and International Classification of Diseases tenth revision (ICD-10)/Korean Classification of Diseases-7 (KCD-7). Methods: We compared the granularity between SNOMED CT and ICD-10 for epilepsy by counting the number of SNOMED CT concepts mapped to one ICD-10 code. Next, we created epilepsy patient cohorts by selecting all patients who had at least one code included in the concept sets defined using each vocabulary. We set patient cohorts generated by local codes as the reference to evaluate the patient cohorts generated using SNOMED CT and ICD-10/KCD-7. We compared the number of patients, the prevalence of epilepsy, and the age distribution between patient cohorts by year. Results: In terms of the cohort size, the match rate with the reference cohort was approximately 99.2% for SNOMED CT and 94.0% for ICD-10/KDC7. From 2010 to 2019, the mean prevalence of epilepsy defined using the local codes, SNOMED CT, and ICD-10/KCD-7 was 0.889%, 0.891% and 0.923%, respectively. The age distribution of epilepsy patients showed no significant difference between the cohorts defined using local codes or SNOMED CT, but the ICD-9/KCD-7-generated cohort showed a substantial gap in the age distribution of patients with epilepsy compared to the cohort generated using the local codes. Conclusions: The number and age distribution of patients were substantially different from the reference when we used ICD-10/KCD-7 codes, but not when we used SNOMED CT concepts. Therefore, SNOMED CT is more suitable for representing clinical ideas and conducting clinical studies than ICD-10/KCD-7.
Cancer Risk Score Prediction Based on a Single-Nucleotide Polymorphism Network
Authors: Mahesworo Bharuno , Budiarto Arif , Hidayat Alam Ahmad , Pardamean Bens
Published: August 2022

Objectives: Genome-wide association studies (GWAS) are performed to study the associations between genetic variants with respect to certain phenotypic traits such as cancer. However, the method that is commonly used in GWAS assumes that certain traits are solely affected by a single mutation. We propose a network analysis method, in which we generate association networks of single-nucleotide polymorphisms (SNPs) that can differentiate case and control groups. We hypothesize that certain phenotypic traits are attributable to mutations in groups of associated SNPs. Methods: We propose a method based on a network analysis framework to study SNP-SNP interactions related to cancer incidence. We employed logistic regression to measure the significance of all SNP pairs from GWAS for the incidence of colorectal cancer and computed a cancer risk score based on the generated SNP networks. Results: We demonstrated our method in a dataset from a case-control study of colorectal cancer in the South Sulawesi population. From the GWAS results, 20,094 pairs of 200 SNPs were created. We obtained one cluster containing four pairs of five SNPs that passed the filtering threshold based on their p-values. A locus on chromosome 12 (12:54410007) was found to be strongly connected to the four variants on chromosome 1. A polygenic risk score was computed from the five SNPs, and a significant difference in colorectal cancer risk was obtained between the case and control groups. Conclusions: Our results demonstrate the applicability of our method to understand SNP-SNP interactions and compute risk scores for various types of cancer.
МОДЕЛЮВАННЯ МАРШРУТІВ ТРАНСПОРТНО-ЛОГІСТИЧНОЇ СИСТЕМИ ПОСТАЧАНЬ ШВИДКОПСУВНИХ ХАРЧОВИХ ПРОДУКТІВ
Authors: Загурський Олег , Загурська Світлана
Published: August 2022

Складність організації транспортно-логістичних систем постачань швидкопсувних харчових продуктів обумовлена, з одного боку, – участю великої кількості ланок у ланцюзі, а з іншого боку, – особливостями швидкопсувних вантажів, а саме: розпорошеність пунктів виробництва швидкопсувних харчових продуктів; сезонність виникнення вантажопотоків; складність узгодження процесів навантаження-вивантаження на взаємодіючих видах транспорту; недетерміноване прибуття рухомого складу до пунктів перевалки; недетермінований режим підвезення вантажів до оптових точок збору; необхідність проходження фітосанітарного та ветеринарного контролю при перетині державних кордоні, тощо. Побудова ефективної моделі транспортно-логістичної системи постачань швидкопсувних харчових продуктів полягає у знаходженні найкращого варіанту її функціонування з безлічі можливих, враховуючи, що: час циклу виконання замовлення за відхиленнями від заявлених замовником термінів і кількість запасів в транспортно-логістичній системі, мають бути мінімально допустимими. Відповідно постає задача поєднання оптимальних логістичних процесів з оптимально необхідною кількістю продуктів, розмір яких визначається поточними потребами клієнтів, тобто в урівноваженні витрат постачання з витратами зберігання. В статті розглянуто проблему побудови ефективного транспортного процесу в ланцюгах постачань швидкопсувних харчових продуктів. Запропоновано економіко-математичну модель, що дає змогу, задля уникнення пробок і заторів під час руху, визначати час знаходження транспорту в дорозі, мінімальний інтервал часу руху транспортного засобу по магістралі, максимальну кількість транспортних засобів, що можуть одночасно знаходитися на трасі та інші параметри необхідні для вирішення конкретного завдання у транспортно-логістичній системі постачань швидкопсувних харчових продуктів. Крім того, вона забезпечує найкращу комбінацію ціна-час-відстань для ефективної роботи ланцюга постачань швидкопсувних харчових продуктів.
ДО ПРИРОДИ СИЛИ ПРИСКОРЕНОГО РОЗШИРЕННЯ ВСЕСВІТУ І ФІЗИЧНОГО МЕХАНІЗМУ УТВОРЕННЯ «КОСМІЧНОЇ ПАВУТИНИ»
Authors: Карпенко Іван
Published: August 2022

Показано, що отримана в рамках польової теорії тяжіння модифікована формула тяжіння Ньютона (МФТН) є динамічно прийнятною. Згідно неї для випадку однорідного статичного Всесвіту прискорення на нескінченності прямує до нуля, а значення гравітаційного потенціалу до величини, що дорівнює половині квадрату швидкості світла. Така поведінка потенціалу є сприятливою передумовою для переходу Всесвіту з нестійкого статичного стану в динамічний стан розширення (розтягування) всієї «тканини» вселенського простору. Розширення Всесвіту розглядається як його внутрішня властивість. Детальніше розглянуто як відбувається щільнісна фрагментація структури Всесвіту – утворення об'ємних космічних порожнин та павутини (комірчастої щільнісної структури). Показано, що не весь простір однорідного Всесвіту впливає на величину поля в довільній точці всередині порожнини. В статичному Всесвіті такий вплив мають лише прилеглі до центру порожнини маси, що знаходяться на відстані не більше трьох радіусів кулястої порожнини. Досліджується природа сили, що призводить до прискореного розбігу галактик. Поява сили розтягування («відштовхувальної») відбувається у випадку, коли щільність зовнішніх мас більша за щільність прилеглих до центру будь-якої кулі всередині Всесвіту внутрішніх мас. У однорідному Всесвіті таке збільшення можливе тільки з урахуванням релятивістської енергії галактик, що рухаються. Оскільки з віддаленням від точки початку координат швидкості галактик збільшуються, то відповідно і їхня релятивістська маса також збільшується. Тому в Всесвіті, що розширюється, щільність зовнішніх мас для будь-якої кулі всередині Всесвіту завжди більша щільності внутрішніх мас. Ця відмінність супроводжується появою спрямованого в усі сторони від початку координат прискорення розтягування, тим більшого, чим далі знаходиться галактика від початку координат. Релятивістське збільшення віддалених мас відбувається щодо будь-якої точки Всесвіту. Тому середнє значення щільності речовини в динамічному Всесвіті буде значно більше, ніж у статичному Всесвіті. Це полегшує розуміння того факту, що щільність спостережуваної речовини у Всесвіті значно менша за необхідне для існування плоского Всесвіту критичне значення щільності. У нашому випадку роль необхідної «добавки», або «темної енергії» виконує релятивістська енергія динамічного Всесвіту. Одночасно з силою розтягування на досліджувану галактику діє і сила тяжіння з боку внутрішніх мас. Певним «вододілом» між порівняльним впливом сил гравітаційного тяжіння і розтягування є точка малого гравітаційного радіуса, у якій в статичному Всесвіті прискорення тяжіння перериває своє зростання і починає зменшуватися, тоді як прискорення розтягування продовжує зростати. Ця точка поділяє Всесвіт на ближній і дальній підпростори. Якщо Всесвіт залишався плоским протягом, наприклад, фрідманівського часу його існування, то на тлі Всесвіту, що розширюється, зберігався і поділ простору на ближній підпростір з переважанням сил тяжіння і дальній – з переважанням сил розтягування.
ЕКОЛОГО-ПРАВОВІ ПРОБЛЕМИ СТАЛОГО РОЗВИТКУ МІСТ І РЕГІОНІВ В УМОВАХ ПОВОЄННОГО ВІДНОВЛЕННЯ
Authors: Кірін Роман , Трегуб Олександр
Published: August 2022

У статті розглядаються ключові еколого-правові проблеми сталого розвитку міст і регіонів в умовах повоєнного відновлення. Досліджено питання Європейського зеленого курсу та декарбонізації економіки як важелю впливу на сучасну еколого-правову систему України. Уточнено, що надро-енергетичні, електроенергетичні, господарсько-енергетичні, економіко-енергетичні відносини, а також відносини в сфері теплозабезпечення потребують першочергової уваги в рамках Європейського зеленого курсу та декарбонізації економіки. Охарактеризовано співпрацю України та ЄС в галузі забезпечення екологічної безпеки постконфліктних міст і регіонів. Аргументовано, що така співпраця передбачає передусім реалізацію екологічних положень Угоди про асоціацію з ЄС з урахуванням того, що планована діяльність, спрямована виключно на ліквідацію наслідків військових дій на території та в період їх проведення, не підлягає оцінці впливу на довкілля. Здійснено аналіз еколого-правових проблем сталого розвитку вугільних регіонів в умовах економічної трансформації. Обґрунтовано висновки щодо мілітарної трансформації техногенно-екологічної безпеки постконфліктних міст і регіонів. Конкретизовано, що найгострішою проблемою техногенно-екологічної безпеки постконфліктних територій є мілітаристське забруднення, на усунення якого необхідно спрямувати заходи військового, оперативного та гуманітарного розмінування. Проаналізовано еколого-правові проблеми сталого поводження з промисловими відходами в містах в умовах повоєнного відновлення. Розглянуто питання підвищення ефективності поводження з відходами видобутку, збагачення та переробки мінеральної сировини (мінеральними відходами). Запропоновано створення у складі спеціального фонду Державного бюджету України Державного фонду поводження з мінеральними відходами, що дозволить акумулювати ресурси безпосередньо для фінансування природоохоронних заходів у цій сфері.
ПРОВЕДЕННЯ АНАЛІЗУ РЕГУЛЯТОРНОГО ВПЛИВУ В КРАЇНАХ ОЕСР: ПРАКТИЧНИЙ ДОСВІД ДЛЯ УКРАЇНИ
Authors: Стасюк Ольга , Чмирьова Лариса , Федяй Наталя
Published: August 2022

В статті основну увагу зосереджено на дослідженні особливостей досвіду впровадження аналізу регуляторного впливу нормативно-правових актів в окремих країнах ОЕСР, зокрема Австралії та Литві. Розкрито сутність процесу аналізу регуляторного впливу, який є сучасним інструментом регуляторної політики, що допомагає урядам приймати виважені рішення та зменшувати ризики від впровадження нормативно-правових актів для підвищення ефективності господарської діяльності. Досвід країн ОЕСР показує, що послідовне впровадження зазначеного інструменту покращує якість регуляторної політики. Обґрунтовано необхідність впровадження практик та стандартів ОЕСР щодо аналізу регуляторного впливу в українське законодавство. Подальше удосконалення аналізу регуляторного впливу для України стане важливим кроком в процесі узгодження його з практикою та стандартами ОЕСР та допоможе зменшити ризики, пов’язані з виконанням значної кількості нових регуляторних положень ОЕСР. Оцінку досвіду впровадження аналізу регуляторного впливу здійснено на основі виділених структурних елементів аналізу регуляторного впливу: мета аналізу регуляторного впливу; характеристика становлення аналізу регуляторного впливу; визначення предмету або сфери діяльності нормативно-правового акту; визначення інституцій, які займаються питаннями аналізу регуляторного впливу; огляд інструментів; розкриття методичних особливостей та джерел інформації. Детально розглянуто основні інструменти аналізу регуляторного впливу, що використовуються в Австралії та Литві: публічні консультації, регуляторна “гільйотина”, впровадження Свідоцтв та Анкет оцінки впливу, які використовуються при проведенні базового та розширеного аналізу регуляторного впливу.
PID ve Kayan Kipli Kontrol Kullanarak DC Motor Besleme Amaçlı Bir PV Sistemin Tasarlanması
Authors: AKGÜN Ahmet , KIRÇAY Ali
Published: August 2022

Bu çalışmada PID ve Kayan Kipli kontrol kullanarak DC motor besleme amaçlı bir PV sistem tasarımı gerçekleştirilmiştir. Çalışmada değişen sıcaklık (45°C, 25°C) ve ışınım (1000W/m2, 800 W/m2) değerleri altında PV panellerden üretilen DC gerilim ile DC-DC yükseltici dönüştürücü yardımıyla ilk önce lityum iyon batarya şarj edilmiştir. PV panellerden olabilecek en yüksek gücü elde etmek için yapay sinir ağları (YSA) maksimum güç noktası takibi (MPPT) algoritması kullanılmıştır. Daha sonra DC motor beslenmesi için şarj edilen batarya gerilimi PID kontrollü yükseltici dönüştürücü ile yükseltilmiş ve kayan kipli kontrol kullanarak düşürücü dönüştürücünün çıkışında sabit akım ve gerilim değeri elde edilmiştir. Yapılan tüm çalışmalar Matlab/simulink ortamında gerçekleştirilmiştir.
Survey on Face and Fingerprint based Person Identification System
Authors: N V Suchetha , K S Anusha , P Deekshitha , P S Deepika , Naik Pavitra Gopal
Published: August 2022

Biometric technologies are commonly used to upgrade the system security by allowing people to be recognised. Multi-modal biometric system based on face and fingerprint biometric attributes are included in this survey report. A camera is used to capture the pictures of the faces in the system. The fingerprint obtained from the fingerprint dataset is cross-checked once the input face is recognised to authenticate the identification. The characteristics of the fingerprint and face are retrieved using haar transformation approach. Score level fusion with real-time datasets determines the final conclusion.
Doutorando e maratonista: ideias e reflexões sobre uma experiência
Authors: Brito Clovis
Published: August 2022

O presente texto, que tem como objetivo apresentar uma correlação entre o percurso de um maratonista e a trajetória de um doutorando, foi realizado por meio de um relato de experiência de um professor que passou por ambos os caminhos. O artigo se divide em três partes: no primeiro tópico é apresentado o que é um doutorado e como funciona o trajeto de um doutorando, ou seja, da entrada no programa até a defesa de tese. O segundo tópico trata da maratona e discorre sobre o que é esta prova do atletismo e como funciona um treinamento para tal evento. No último tópico conclui-se o artigo apontando algumas correlações possíveis entre um doutorando e um maratonista, tais como: a livre escolha para participar das duas atividades; o orientador e o treinador; a vida do doutorando e a vida do maratonista; as dores de um sono desregulado de um doutorando e as dores de um maratonista; o dia da defesa e o dia da corrida; o sentimento de felicidade no final da maratona ou o de doutorado.
Music as Ludic Didactic Strategy for the Acquisition of Vocabulary in English
Authors: Paz Zambrano Graciela Manuela
Published: August 2022

The main objective of this research is to analyze the use of music as a ludic didactic strategy for the acquisition of vocabulary of the English language as a foreign language in the students of the second level at “Dr. Gonzalo Abad Grijalva” high school, which arises due to the little knowledge of vocabulary that they have in this language. The methodological proposal has a quantitative approach, with a descriptive reach due to the information obtained through bibliographic sources and digital degree theses acquired from the Internet. The results obtained from a survey addressed to students are analyzed; which made it possible to know that music is a strategy that gives students the opportunity to increase vocabulary. The survey was carried out as a research technique, with a questionnaire of eight questions addressed to students, with a polyatomic scale. The results obtained showed that activities based on the use of songs in English do affect students and make them feel motivated when using them as a learning tool. In conclusion, it was found that the learners are at a level where they can use songs in English, which enables them to acquire vocabulary and develop the skills of learning this language, promoting oral fluency naturally.
Automated Electronic System for Census Process
Authors: Anushree Sonurlekar  , Arpita Sinai Kerkar  , Anukeerti Sharma  , Joel Pires  , Amita Dessai
Published: August 2022

Present-day censuses are generally completed in physical modes wherein the authorities need to go
from door to door to gather the necessary information. All the Censuses to date have been directed
similarly, and in this way require a ton of on-ground authorities for the same. Likewise, a ton of desk
work is needed to have been kept up within this interaction making it a bulky interaction. There have
been ongoing advancements in having an application for completing the Census, yet even that has
numerous limits. Since for this situation individuals can get to the application and give the responses
all alone, it can prompt off-base or deceiving information bringing about the failure of the reviews.
Likewise, not all individuals can utilize portable applications with no help. Also, it has been
referenced in the Lok Sabha that over 25000 villages in India still lack mobile and internet coverage.
Because of this absence of web entrance in distant regions, the past conventional techniques for taking
overviews are still in practice. Hence, in this paper, we introduce a new approach, an Automated
survey system for the census process. The proposed system is faster and more authentic than the
traditional process of pen and paper. All the data is collected digitally and stored directly into datasets,
therefore data storage and retrieval are no longer cumbersome. This collected data is far easier to
analyze. The authenticity is provided by Biometric sensors.
ANALISIS TINGKAT KENYAMAN TERMAL DI KOTA PALEMBANG BERDASARKAN INDEX THI (TEMPERATURE HUMIDITY INDEX)
Authors: Melinda Shelin
Published: August 2022

Pertumbuhan penduduk di Kota Palembang provinsi Sumatera Selatan makin lama makin meningkat, dari data statistik menunjukkan terjadi peningkatan penduduk tahun 2020 menjadi 1.868.848 jiwa. Peningkatan jumlah penduduk menjadi salah satu pemicu terjadinya perluasan lahan dalam pembangunan seperti pemukiman penduduk dan membuat ruang terbuka hijau berkurang. Peningkatan jumlah penduduk dan perluasan lahan di kota Palembang tanpa diikuti keseimbangan dari lingkungan akan menimbulkan pemanasan perkotaan yang disebabkan oleh perubahan atau peningkatan suhu udara yang menyebabkan ketidaknyamanan disuatu wilayah. Penelitian ini bertujuan untuk mengetahui bagaimana tingkat kenyamanan termal serta kecendrungannya di Kota Palembang dengan menggunakan indeks THI. Dalam penelitian ini menggunakan dua variable iklim untuk mengitung indeks THI, yaitu suhu udara rata-rata harian dan kelembaban relatif harian selama periode 1991 – 2020 dari Stasiun BMKG Klimatologi Palembang. Berdasarkan hasil indeks THI, secara umum tingkat kenyamanan didominasi oleh kategori sebagian nyaman sebanyak 73.9% atau 270 hari/tahun dan kecendrungan THI setiap tahuhnya mengalami peningkatan dengan peninkatan suhunya sebesar 0.03°C/tahun.