bluuebunny/crossref_metadata_2025 huggingface dataset:
ADIPOKINES AND THEIR RELATIONSHIP WITH RHEUMATOID ARTHRITIS
Authors: Milhomem Giovanna Martins , Silva Asafe Ribeiro Dias da , Veríssimo Gustavo Vital , Mariano Melissa Silva , Caldas Sarah Cardoso , Cruvinel Wilson de Melo , Borges Leonardo Luiz , Silva Vinicius Barreto da , Gomes Clayson Moura
Published: November 2024

Rheumatoid Arthritis (RA) is a chronic inflammatory condition affecting the joints, leading to progressive destruction of cartilage and bones. This multifaceted and complex disease involves processes such as continuous inflammation, angiogenesis, cartilage degradation, and bone erosion in its pathogenesis. Adipocytes, which are cells present in adipose tissue, play a crucial role in RA by secreting adipokines, which are bioactive proteins and immunological molecules that can mediate inflammation and immune response. Among the most studied adipokines are the leptin and adiponectin, known for their effects on metabolism regulation and inflammatory response. Studies have explored the relationship between adipokines and the treatment of RA, investigating their potential for therapeutic targets. For instance, high levels of leptin have been associated with disease activity and pro-inflammatory cytokine production in the joints. Elevated adiponectin levels have been linked to RA severity, suggesting its potential role in disease progression. Treatments for RA include medications such as methotrexate and biologic agents, primarily targeting inflammatory cytokines. Recent therapeutic approaches have explored the possibility of modulating adipokine levels as an additional strategy to control inflammation and protect joints. For example, leptin signaling inhibitors have shown protective effects on cartilage in experimental models of RA. Although adipokines have emerged as important mediators in RA pathophysiology, many questions remain unanswered regarding their specific role and clinical relevance. Further research is needed to better understand how these molecules can be utilized as therapeutic targets in RA, as well as to identify biomarkers that may assist in disease diagnosis and monitoring.
Las remesas a América Latina y el Caribe en 2024: disminuyendo el ritmo de crecimiento
Authors: Maldonado René , Harris Jeremy
Published: November 2024

Las remesas que reciben las familias de emigrantes de los países de América Latina y el Caribe (ALC) contribuyen de manera importante a reducir su pobreza, y son uno de los motivos principales de la migración internacional. Después de varios años de crecimiento elevado en la época de la pandemia, en 2024 se observa una desaceleración del crecimiento de los flujos de las remesas hacia la región de América Latina y el Caribe. Se presenta una proyección de la evolución de las remesas hacia los países de ALC en 2024, con un análisis de los determinantes de los flujos y el impacto que tienen los cambios en las variables macroeconómicas sobre el poder adquisitivo de las remesas para las familias receptoras. Adicional se comparte unos hechos estilizados del comportamiento de envío de remesas en base a varias encuestas de personas que mandan remesas a varios países de la región.
Tecnologias Digitais em Ambientes Prisionais: uma RSL sobre a Interação de Pessoas Presas com Ferramentas Educacionais
Authors: Siqueira Fabio , Oliveira Márcia Gonçalves de , Amado Manuella Villar
Published: November 2024

A Lei de Execução Penal (LEP) assegura às pessoas privadas de liberdade o direito à educação, enquanto a Base Nacional Comum Curricular (BNCC) incentiva o desenvolvimento de Tecnologias Digitais de Informação e Comunicação (TDIC). Este estudo realiza uma Revisão Sistemática de Literatura (RSL), em um intervalo de dez anos, para investigar como essas diretrizes são aplicadas em ambientes prisionais. A pesquisa apresenta ações inovadoras que, mesmo sob rígidas normas de segurança, buscam capacitar os internos no uso de tecnologias. A RSL seguiu critérios rigorosos de inclusão e exclusão, abrangendo oito estudos, nacionais e internacionais, que revelaram achados importantes sobre os desafios e possibilidades para uso de tecnologias educacionais em contextos prisionais.
 
Palavras-chave:Educação. Prisão. Tecnologia. Ressocialização.
Tajemnice amortyzacji
Authors: Iwin-Garzyńska Jolanta
Published: November 2024

Depreciation secrets
The secret of depreciation lies in the behavior of business entities in the allocation and use of resources resulting from both the process of releasing depreciation capital from tangible fixed assets and the tax effect of depreciation. Resources that make up depreciation capital and constitute the potential and financial picture of a company. On the other hand, to understand the mystery of depreciation is to grasp it more fully and see its power. It is also important for business entities to be aware of their resources and manage them properly, especially in an uncertain environment.
The purpose of the study is to analyze the financial phenomena occurring in the enterprise as a result of depreciation processes and to grasp their mystery by pointing to the capital potential created by depreciation.
Asymptotic analysis of monotonic stability of the amplitude of pendulum oscillations with small nonlinear damping
Authors: Lyubimov Vladislav V.
Published: November 2024

An ordinary differential equation of the second order describing free oscillations of a pendulum with small damping in the form of a third-degree polynomial is considered. The aim of the work is to analyze the monotonic stability of the amplitude of free oscillations of the pendulum with small damping, having one degree of freedom. The equation of the pendulum oscillations is written as a system of amplitude-phase equations. Then, the equation for the oscillation amplitude is averaged over the fast phase. By analyzing the expressions for the first- and second-order derivatives for the averaged amplitude, the monotonic stability of the pendulum oscillations is analyzed. The following main results are obtained in the work: the conditions of the monotonic stability of the pendulum oscillation amplitude are formulated, the region of monotonic stability is described, the number of qualitatively different cases of monotonic stability is determined, the condition for the attainability of a stable equilibrium position by the pendulum is considered. Verification of the results of the work confirmed their correctness. At the same time, they have both theoretical and applied significance. For example, they can be used in studying the stability of self-oscillations of the pendulum systems.
Complex analysis of the vessel's shaft
Authors: Fishchenko Artem M. , Grinek Anna V. , Boychuk Igor' P.
Published: November 2024

The article considers the impact of operating loads on a ship's shaft. Preliminary static, dynamic, modal and harmonic calculations were performed in the finite element modeling environment. Data on the shaft's natural vibration frequencies, as well as load values in a given frequency range and structure deformations in the operating mode were obtained. A complex analysis of the ship's shaft has been carried out. Data on the frequencies of natural vibrations of the shaft, the values of loads in a given frequency range and deformation of the structure in the operating mode were obtained. According to the data obtained, it is possible to judge the change in the state of the structure during operation.
Amplification of UV radiation and gain mechanisms in ZnO films with loose-packed structure
Authors:   Shubnikov Institute of Crystallography, Zadorozhnaya L.A. , Tarasov A.P. ,   Shubnikov Institute of Crystallography, Lavrikov A.S. ,   Shubnikov Institute of Crystallography, Kanevsky V.M. ,   Shubnikov Institute of Crystallography
Published: November 2024

The modern demands for miniaturization of optoelectronic devices, in particular, for the UV range, are inextricably linked with the improvement of fabrication technologies for the corresponding photonic nano/micro objects and the study of their radiative properties. In this work, the method of pyrolytic carbothermal synthesis, which is a modification of the thermal evaporation method, was used to fabricate microcrystalline ZnO films with laser properties. The influence of the size and packing type of ZnO microcrystallites in the films on their emissive properties were revealed. The films with relatively large microcrystallites (10–15 µm in size on average) were found to exhibit UV amplified spontaneous emission at room temperature. The possibility of additional enhancement of this emission and its two-threshold behavior in loose-packed regions of such films were found for the first time. It was shown that the observed phenomenon is due to the competition between two gain mechanisms, which are assumed to arise predominantly in different regions of microcrystallites as a result of exciton-phonon and exciton-electron interaction processes. As the temperature decreases, the dominant gain mechanism gradually changes to exciton-exciton scattering, regardless of the type of film structure. The results obtained open up the possibilities of the thermal evaporation synthesis to a wider extent and can be useful in interpreting the optical gain mechanisms in ZnO micro- and nanostructures.
Neuroendoscopic Lavage in Hydrocephalus with Ventricular Empyema: A Case Report
Authors: Bal’afif Farhad , Nazwar Tommy A , Wardhana Donny W , Sanjaya Oei Thomas , Mataniari Keneysha Naomi , Saputri Farahiyah Sharfina , Dewi Liliana , Arifani Hisanifa , Triana Ni Nyoman , ‎ Mustofa
Published: November 2024

Introduction: Ventricular empyema, or pyogenic ventriculitis, is a severe condition characterized by pus accumulation in the cerebral ventricles due to intracranial infection, often caused by Gram-negative bacteria. Early diagnosis and treatment are crucial to prevent fatal neurological damage.
Case Report: A 3-month-old infant with severe hydrocephalus and ventricular empyema was admitted with symptoms of seizures, fever, and diarrhea. Initial examination showed decreased consciousness and significant leukocytosis. CT scans confirmed severe hydrocephalus and ventricular empyema. Despite resistance to standard antibiotics, neuroendoscopic lavage (NEL) and bilateral external ventricular drainage (EVD) were performed, leading to substantial improvement.
Discussion: The patient’s condition improved significantly post-surgery, with a decrease in leukocyte count and resolution of empyema as shown in follow-up imaging. This case demonstrates the efficacy of NEL in treating complex pediatric neurosurgical conditions.
Conclusion: NEL proves to be an effective treatment for intraventricular empyema in pediatric patients, improving clinical outcomes and reducing hospital stays. The success of this approach emphasizes the need for tailored neurosurgical interventions and regular follow-ups to ensure patient recovery and prevent recurrence.
Druga strona medalu. O krytyce instytucjonalnej
Authors: Pałka Magdalena
Published: November 2024

Krytyka kojarzona jest zazwyczaj z oceną i interpretacją różnorodnych tekstów kultury. W niniejszym artykule chciałabym zwrócić uwagę na drugą stronę medalu – to, w jaki sposób i w jakich warunkach teksty kultury są wytwarzane. Tematyką tą zajmuje się krytyka instytucjonalna, wcześniej rozumiana jako nurt w sztuce współczesnej, a dziś uzupełniona o działania podejmowane przez pracowników, badaczy i odbiorców kultury – które nie korzystając z artystycznych środków wyrazu, znacząco i ciekawie uzupełniają współczesną refleksję na temat funkcjonowania instytucji sztuki. Dziś więc można już mówić o III fali krytyki instytucjonalnej, łączącej perspektywę artystyczną, badawczą i społeczną. W pierwszej części artykułu opiszę zjawisko artystycznej krytyki instytucjonalnej, jej istotę, zarys historyczny i dzisiejszą problematykę z polskiej perspektywy. W drugiej – przyjrzę się polskim przykładom krytyczno-instytucjonalnych inicjatyw pracowników czy badaczy kultury.
Echocardiographic Effects of Tiletamine-zolazepam and Ketamine-diazepam in Dogs Undergoing Ovariohysterectomy
Authors: Rani Monika , Tiwari Deepak Kumar , Arora Neeraj , Saharan Sandeep , N. Sachin Kumar
Published: November 2024

Background: Echocardiography is ultrasound of heart. In order to promote reduction in mortality rates due to anaesthesia, it is essential to understand the potential depressant effects of anaesthetic drugs on the cardiovascular system, so that anaesthetic procedures are conducted in the best possible way. Cardiac monitoring during surgery offers rapid and safe information about the alterations that may appear during the surgical procedure that can affect cardiac functions. Methods: The present study was undertaken to evaluate the echocardiographic effects of Tiletamine-zolazepam and Ketamine-diazepam anaesthetic combination in twelve healthy female dogs for ovariohysterectomy. These twelve dogs were randomly allotted to two equal groups irrespective of age, breed and body weight. Dogs were anaesthetized with Tiletamine-zolazepam (7.5 mg/kg, IV) in group 1 and Ketamine (5.0 mg/kg, IV)-Diazepam (0.5 mg/kg, IV) in group II. Atropine sulphate (0.04 mg/kg IM) followed by butorphanol (0.2 mg/kg IM) after 10 minutes was used as preanaesthetic drugs. Echocardiographic indices were recorded at different time intervals during the study period. Result: Non-significant changes were found in both systolic and diastolic functions. Thus, present findings suggested that Tiletamine-Zolazepam and Ketamine-Diazepam anaesthetic combinations provided good cardiovascular stability in dogs undergoing ovariohysterectomy.
The Immature Stages of Sarcophaga dux (Diptera; Sarcophagidae): A Proposed Nutritional Source for Poultry
Authors: Alotaibi F. , Alkuriji M. , Ahmed A. , Almuhysh F. , Almannaa S. , Bashir M.A. , Alajmi R.
Published: November 2024

Background: Insects, particularly those belonging to the order Diptera, offer a promising alternative protein source for poultry with numerous advantages. Among these, Sarcophaga dux (Diptera: Sarcophagidae), a widely distributed global dipteran species, including Saudi Arabia, exhibits potential for waste management. This study was conducted to investigate the nutritional values of both larval and pupal stages of S. dux as well as the feed intake (FI) and the feed conversion ratio (FCR). S. dux flies (≈170 to 200 newly hatched larvae) were reared in standardized laboratory conditions until reaching the pupal stage. Methods: The daily feed intake was calculated for each larvae replicate and FCR was measured on the last day of the 3rd larval instar. Larvae and pupae from each replicate were subject to the proximate analysis, amino acids and minerals. Results indicated a progressive increase in FI throughout the development period, except for the last day of the 3rd larval instar. Result: The FCR demonstrated a higher value comparing to previous study. Furthermore, both larval and pupal stages exhibited high crude protein, lipid content and crude fibre with low dry matter and elevated ash content. The amino acid and mineral contents were also high, with low levels of heavy metals. Notably, the pupal stage displayed superior results in this study. These results may indicate that larvae and pupae of S. dux are promising sources of protein, minerals and potentially other essential nutrients which, in fact, suggest it as a nutritionally valuable food sources for poultry. Upon comparing the larval and pupal stages, it is evident that essential minerals are generally abundant in both stages except for manganese (Mn), which was found to be highest in pupae. However, it is noteworthy that the levels of heavy metals in both stages were low and exhibited no significant difference except for lead (Pb).
The Effects of Varied Neutral Detergent Fiber Levels on Blood Parameters, Nutrient Digestibility, Rumen Fermentation Characteristics and Rumen Tissue Morphology in Lambs
Authors: Alhidary Ibrahim A. , Al-Baadani Hani H. , Alharthi Abdulrahman S. , Aboragah Ahmad A.
Published: November 2024

Background: Neutral detergent fiber is a common analytical measure of feed fiber content, which could play an important role as an energy source, improve the rumen ecosystem and thus improve growth performance of lambs. The aim of this study was to investigate the effects of different levels of neutral detergent fibers on growth performance, blood parameters, nutrient digestibility, volatile fatty acid concentration, ammonia nitrogen, bacterial quantification, gas production and tissue morphology of growing lambs. Methods: Seventy-two Awassi lambs of weaning age were randomly assigned to three experimental feeds with different levels of neutral detergent fiber: low (210 g/kg), medium (280 g/kg) and high (350 g/kg), each with eight replicates in a completely randomized design. The growth performance parameters were evaluated over a trial period of 84 days. At the end of the trial, hematological and serum biochemical parameters and nutrient digestibility were evaluated. In addition, rumen fermentation characteristics, including pH, ammonia-nitrogen, gas production, volatile fatty acids, bacterial quantification and indices of rumen morphology indices were measured. Result: The results showed that lambs fed a medium-neutral detergent fiber feed had better growth performance (p less than 0.05). In addition, this experimental feed showed improvements in some blood parameters (WBC, RBC, HGB, TP, GLOB and GLU) and nutrient digestibility with the exception of crude protein and ash (p less than 0.05). Rumen fermentation characteristics and rumen morphology were also positively influenced by the medium- neutral detergent fiber level (p less than 0.05). These results indicate that a medium level of neutral detergent fiber (280 g/kg) is essential for optimal growth, health and rumen development in growing lambs.
Una aproximación al liderazgo educativo en experiencias de danza artivista acompañadas pedagógicamente
Authors: Burón-Vidal Miguel
Published: November 2024

En este trabajo se exploran los significados atribuidos al liderazgo educativo por parte de colectivos artivistas y de quienes facilitan pedagógicamente su actividad en ámbitos sociocomunitarios. Con el objetivo de analizar —desde una perspectiva intercultural crítica y situada— el sentido de diferentes estrategias y estilos de liderazgo, se ha acudido a las voces de quienes protagonizan estas experiencias: tanto adolescentes y jóvenes integrantes de grupos de danzas urbanas como figuras educativas de referencia para estos procesos personales y colectivos. Para esto, se ha empleado una metodología cualitativa a partir de observaciones participantes, entrevistas en profundidad y cuestionarios. Se ensayan algunas propuestas de enfoque acerca de las concepciones inclusiva y distributiva de los liderazgos sondeados, avanzando nuevos sentidos y posibilidades estratégicas que pudieran contribuir a la reflexión y la acción educativa formal e informal.
Metodika rada školskog pedagoga na osnovnim akademskim studijama pedagogije fakulteta filozofske orijentacije
Authors: Cvjetinović Vesna Zoran , Škipina Daliborka B.
Published: November 2024

Rad predstavlja komparativnu analizu silabusa studijskog predmeta Metodika rada školskog pedagoga na prvom ciklusu studija Filozofskog fakulteta u Istočnom Sarajevu, Novom Sadu, Nišu, Kosovskoj Mitrovici, Beogradu i Nikšiću. Cilj rada je da se ispita usklađenost silabusa za studijski predmet Metodika rada školskog pedagoga na izabranim fakultetima. Metoda istraživanja u radu je teorijska analiza, a tehnika je analiza sadržaja silabusa za pomenuti predmet. Komparativna analiza urađena je na osnovu sljedećih jedinica analize: status predmeta, godina studija i semestar u kome se predmet sluša, broj ECTS/ESPB bodova, fond časova (predavanja i vježbe), cilj predmeta, uslovljenost, nastavne metode, sadržaj predmeta (područja: planiranje i programiranje rada škole, saradnja pedagoga sa nastavnicima, učenicima, roditeljima, analitičko-istraživački rad) i provjere i ocjenjivanje znanja studenata. Rezultati istraživanja pokazali su da u odnosu na ispitivane jedinice analize postoje određene razlike i da stepen usaglašenosti sadržaja silabusa za predmet Metodika rada školskog pedagoga varira u odnosu na ispitivane oblasti. Viši nivo usaglašenosti ostvaren je u domenu statusa predmeta, godine studija i semestra u kome se predmet sluša, broja ECTS/ESPB bodova, fonda časova (predavanja i vježbe), cilja predmeta, sadržaja predmeta, dok je djelimična usaglašenost konstatovana kod ostalih ispitivanih jedinica analize.
Creativity in the classroom: Schools of curious delight
Authors: Omeragić Abdulah
Published: November 2024

Creativity in teaching is a very important topic that is starting to be discussed more and more intensively in the pedagogical scientific discourse. The future of our world is uncertain, and if we want the new generations to be ready to respond adequately to its challenges, we need to pay more attention to education for creativity. This article offers a review of the book Creativity in the Classroom: Schools of Curious Delight (2021) by Alane J. Starko, professor of educational psychology in the Department of Teacher Education at Eastern Michigan University in USA. In the book, the author considers the theoretical concepts of creativity as well as their practical application in teaching. She reflects on previous understandings of this phenomenon, new insights from neuroscience, revolutionary teaching methods, but also some positive well-established practices that we have been following for years. In her book, professor Starko explicitly claims that creativity is developed and learned, and that we all have the potential to be creative. She promotes the idea that creativity is not limited to arts, which is why she offers advice on how to develop it in all subject areas. This book review should serve as an inspiration to all teachers, and especially to all educators to start exploring creativity in teaching more intensively.
Аkademske emocije u vannastavnim aktivnostima i školski uspjeh učenika
Authors: Mihajlović Tatjana V. , Skrobonja Jasna , Vukanović Nemanja D. , Dragić Želimir Ž.
Published: November 2024

Cilj istraživanja je ispitati povezanost između samoprocjena učenika o prisutnosti prijatnih i neprijatnih emocija u vannastavnim aktivnostima sa opštim školskim uspjehom i školskim uspjehom iz pojedinih nastavnih predmeta, te da li postoji povezanost između procjena i samoprocjena učenika o vrijednostima vannastavnih aktivnosti sa opštim školskim uspjehom i školskim uspjehom iz pojedinih nastavnih predmeta. Primijenjen je instrument Upitnik vannastavnih aktivnosti u školi (VNAUŠ), kao i evidentne liste za bilježenje zaključnih ocjena i opšteg školskog uspjeha. Rezultati istraživanja ukazuju da su ostvarene slјedeće korelacije: pozitivna veza između opšteg školskog uspjeha i prijatnih emocija, negativna veza između opšteg školskog uspjeha i neprijatnih emocija i pozitivna veza između procjena i samoprocjena učenika o vrijednostima vannastavnih aktivnosti sa opštim školskim uspjehom i većim dijelom pozitivna veza sa školskim uspjehom iz pojedinih nastavnih predmeta. Dobijeni nalazi istraživanja ukazuju na potrebu kvalitetnijih programa vannastavnih aktivnosti u cilju podsticanja svih potencijala učenikove ličnosti, zadovoljavanja njegovih potreba i interesovanja u želji za samoaktualizacijom. U narednim istraživanjima neophodno je primijeniti različite kooperativne modele, zatim programe socijalno-emocionalnog učenja namijenjenog učenicima, te eksperimentalno provjeriti njihovu efikasnost u vaspitno-obrazovnom radu u školi.
The Motivation of Elementary School Teachers for the Implementation of the Distance Learning Concept
Authors: Stojanovska Vera , Ikonomoska Angela
Published: November 2024

At the center of this research is the motivation of the teaching staff for the overall organization and implementation of the distance learning concept in elementary schools. This study's sample consists of 252 teachers, 118 of whom are class teachers and 134 of whom are subject teachers from 11 elementary schools. A questionnaire was used to obtain information about teachers' motivation for implementing the distance learning concept. The data obtained from the research was processed using a descriptive and quantitative method. The chi-square test was used to assess the existence or non-existence of a difference in teachers' answers. Based on the obtained results, it was concluded that a large percentage of the teachers were motivated to realize the concept of distance learning, but also that there is a difference in motivation between teachers with different work experience but not between class and subject teachers.
Primena tehnologije u nastavi: pregled faktora na nastavničkom i školskom nivou
Authors: Momčilović Marijana
Published: November 2024

Primena informaciono-komunikacionih tehnologija (IKT) u nastavi na kvalitetan način može doprineti boljim postignućima učenika. Imajući u vidu brojne inicijative u vidu tehnoloških inovacija koje se pojavljuju u obrazovanju, veliki izazov za nastavnike predstavlja ovladavanje veštinama za najbolju moguću primenu IKT-a u nastavi. Faktori školskog okruženja, kao na primer školska politika, podrška škole za korišćenje IKT-a i adekvatni IKT resursi takođe utiču na nastojanje nastavnika za primenu IKT-a. Istraživači različito tumače najznačajnije faktore, kao i odnose među njima. Postavlja se pitanje sveobuhvatnog razumevanja faktora koji imaju efekat na pedagošku implementaciju IKT- a u nastavi. Cilj ovog istraživanja bio je da se analizom relevantne literature izdvoje faktori koji imaju efekte na korišćenje IKT-a u nastavi. Utvrđeni su nastavnički i školski faktori koji doprinose primeni IKT-a u nastavi. Nastavnički faktori predstavljaju medijatorske faktore u odnosu institucionalnih faktora i primene IKT-a u nastavi, dok se od nastavničkih faktora uverenje o IKT samoefikasnosti nastavnika izdvaja kao značajna determinanta. Rad zaključujemo teorijskim i praktičnim implikacijama za buduća istraživanja.
Security of Digital Files: Audio Tampering Detection
Authors: ARGHIRESCU Sebastian-Alexandru
Published: November 2024

In an age where most of the data we interact with daily is stored digitally, methods of checking its authenticity become more and more essential. This is especially true for sound, as the increasing public availability of AI models makes tampering with audio files easier than ever. In this paper, we will be investigating the current landscape of audio forensics as well as our new hardware-based solution for double encoding detection.
Operationalizing the Cyber Threat Landscape: Key Considerations and Challenges in Developing a Specific Organizational Program
Authors: CIUCHI Costel
Published: November 2024

The landscape of cyber threats is multifaceted, encompassing a wide array of attack vectors, including distributed denial of service (DDoS) attacks, phishing, man-in-the-middle attacks, password-based intrusions, remote exploitation, privilege escalation, and malware deployment. As the sophistication of cyber threats continues to advance, coupled with the development of increasingly sophisticated evasion techniques, traditional security mechanisms - such as firewalls, intrusion detection systems, antivirus software, and access control lists - are proving less effective in identifying and mitigating these complex threats. This underscores the urgent need for the development and implementation of innovative, more robust solutions to counteract the growing prevalence of cyber-attacks. The objective of this proposal is to examine the ENISA Cybersecurity Threat Landscape Methodology and explore potential advancements that integrate traditional decision-making frameworks with emerging cybersecurity technologies. As concerns over cyber warfare continue to escalate, nations must adopt adaptable cyber frameworks and methodologies capable of preventing cyber crises. Furthermore, these frameworks should foster greater international collaboration and participation in the ongoing global discourse on cybersecurity.
Analysis of Cyber Threats at the Level of a Distributed Network
Authors: COPACI Constantin-Alin , STĂNCIULESCU Adelaida , BACIVAROV Ioan C.
Published: November 2024

Ensuring a high level of security of the networks and IT systems that underpin the delivery of an organization's essential services has become a necessity that involves integrated, comprehensive approaches, the adoption of new and permanent cyber security strategies, significant financial investments and rapid organizational adaptations and ambitious. This article aims to provide a comprehensive analysis of the cyber security of a distributed computer network within an organization. In this context, the article promotes the implementation of proactive tools to strengthen cyber security at the institutional level.
MANIFESTATIONS OF PEACE, LOVE AND TOLERANCE IN PAKISTANI LITERATURE: IN THE CONTEXT OF CONTEMPORARY SITUATION
Authors:   Institute of Urdu Language & Literature, University of the Punjab, Lahore, Pakistan, Kamran Muhammad
Published: November 2024

If we review the history of Asian literature, the literature created in Pakistan's national language, Urdu, is generally a message of love, peace, tolerance and coexistence. Pakistan's national poet Allama Muhammad Iqbal has declared love as the conqueror of the world in his poetry. The main message of mysticism and knowledge poetry in the regional languages of Pakistan is love and tolerance. The revolutionary poetry of Pakistan's prominent poet Faiz Ahmed Faiz, which is the bearer of positive change in society, calls love and freedom of expression as fundamental human values. Ahmed Nadeem Qasmi in his poetry awakens the consciousness to end the sufferings and deprivations of the common man. Munir Niazi and Ahmed Faraz raise their voices for the creation of an enlightened and moderate society. Amjad Islam Amjad describes love as the most beautiful dream of the human eye. Overall, the main theme of Pakistani poems and ghazals is love and philanthropy. This poetry refutes the general impression of the West, under the influence of which terrorism and intolerance are linked to Pakistani society. In this paper, along with Pakistani literature, the social and cultural landscape of South Asia will also be highlighted.
Akar Konflik Pertambangan Emas di Gunung Tumpang Pitu Banyuwangi
Authors: Setiawan Eko
Published: November 2024

The existence of a gold mine at Mount Tumpang Pitu is a valuable asset for Indonesia, but it faces a negative stigma due to its environmental impacts, including landscape destruction, landslides, and water pollution, leading to conflicts between local communities, companies, and the government. This research aims to analyse the roots of conflict between local communities and mining companies, the impacts of mining, and alternative conflict resolution that can be implemented. The research method used is a literature study, with data collection from books, magazines, reports, and journals related to mining conflicts. The results show that community dissatisfaction with the Banyuwangi Regent's approval of the mining permit, which is considered legally flawed, as well as the negative impacts on the environment and livelihoods, has resulted in divisions among the community and mobilisation of protests. It was also found that the company's approach of prioritising economic profit over ecological and social sustainability contributed to the prolonged conflict. Therefore, government involvement in protecting community rights and monitoring mining activities in line with sustainable development is crucial. Mediation involving neutral third parties and the establishment of special institutions to handle conflicts are also needed to achieve constructive dialogue. This research is expected to provide theoretical insights in understanding mining-related social conflicts and practical benefits for policy makers in formulating more sustainable and inclusive mining policies.
Woman in The Vulnerability and Disaster Risk of Merapi Eruption
Authors: Hastuti Hastuti , Widodo Edi , Giyarsih Sri Rum
Published: November 2024

This study was aimed to depict the characteristics of women's vulnerability, as well as to study and analyze their efforts to reduce the disaster risk of Merapi eruption. This research is a survey research using descriptive quantitative method. The results showed that women were vulnerable in terms of their financial security, particularly due to their lack of bank saving, protection in the place of business, land, and residence. Their social vulnerability was shown by how most of the women and elderly people in the households of the area under study required protection when disaster occurred. The vulnerability in organizations was due to the lack of organizations to care for the women.
Development of E-Module Based on Learning Cycle 6E for the Sub-material of the Distribution of Flora and Fauna in Indonesia and Worldwide for High School Students
Authors: Bella Syintia , Kurnianto Fahmi Arif , Nurdin Elan Artono , Astutik Sri , Apriyanto Bejo
Published: November 2024

This research aims to develop a learning product in the form of an E-Module (Electronic Module) based on the Learning Cycle 6E for the sub-material of the distribution of flora and fauna in Indonesia and worldwide for grade XI high school students with established validity standards. The research method used is Research and Development (R&D) with the ADDIE model, consisting of the analysis, design, development, implementation, and evaluation stages. The analysis stage includes student needs analysis, basic competency analysis, and competency analysis. The design stage involves formulating learning objectives, research and evaluation instruments, and the structure of the E-Module. The development stage includes collecting materials, creating the E-Module, distributing and testing with experts, followed by analysis and revision of the results. The implementation stage involves applying the developed E-Module in a classroom trial with students. The final stage is the evaluation stage, which is conducted to analyze errors during the implementation phase and errors in data collection. This research was conducted at Madrasah Aliyah Negeri 2 Jember with trial subjects being 34 grade XI IPS 4 students. Research instruments used were validation sheets and student response questionnaires. The validation test results of the E-Module by three experts obtained a score of 93.7% for E-Module expert, 98% for content expert, and 100% for learning practitioner, indicating very valid interpretation and suitability for use without revision. The practicality level of the E-Module was determined based on student responses, with a percentage of 92.3% for small group and 93% for large group, categorized as very practical.
ADSORPTIVE AND PHOTOCATALYTIC PROPERTIES OF THE ZnO/BENTONITE/Ag HETEROJUNCTION
Authors: Klimenkov Oleksiy , Ivanenko Iryna
Published: November 2024

The degradation of organic wastewater pollutants from diverse sources represents a critical scientific challenge, particularly in light of the escalating demand for dyes across various industries. Addressing this challenge entails the exploration of efficient and eco-friendly methods to convert organic pollutants into benign and straightforward compounds, leveraging state-of-the-art photocatalysts. The synthesis was conducted via the novel sol-gel method. Structural, crystalline, elemental and phase parameters were analyzed using X-ray analysis, chemical surface characteristics investigated through infrared  spectroscopy, band gap determination performed via diffuse reflectance spectroscopy, and evaluation of adsorption and photocatalytic activity carried out for the semiconductor photocatalyst ZnO and heterojunctions incorporating bentonite. The synthesized photocatalysts were employed for the removal of malachite green dye. Equilibrium studies for adsorption were conducted using Langmuir and Freundlich isotherms, revealing a superior fit with the Langmuir model. The maximum adsorption capacity was determined as 70.4 mg/g using the Langmuir equation. Kinetic parameters indicated that the adsorption of malachite green on bentonite followed a first-order kinetics model where k1=0,152 min-1. The photodegradation efficiency of ZnO, ZnO/bentonite, and Zn/bentonite/Ag was investigated by static experiment under ultraviolet irradiation. Within 60 minutes, a 99.4% photodegradation of the malachite green solution at a concentration of 100 mg/L was achieved using the ternary heterojunction photocatalyst. Remarkably, within just 10 minutes in the presence of the ternary composite, a degree of photocatalytic degradation reaching 72% was attained, which significantly exceeds the results of the binary heterojunction photocatalyst. Thus, the synthesized heterojunction exhibits notable photocatalytic activity, particularly evident within short time intervals. A proposed mechanism for the photocatalytic degradation of malachite green is outlined based on existing literature sources.
DIGITALIZATION OF WATER VENDING MACHINES
Authors: Mudryk Rostyslav , Orestov Yevhen
Published: November 2024

Vending, the sale of goods and services through automated systems, has gained worldwide popularity as a convenient and low-maintenance method of commerce or service delivery. With its wide range of applications, vending can be used in almost all areas of commercial and social life. This article is dedicated to studying the impact of digitalization on the operation of water vending machines. These machines represent a modern way of obtaining safe and physiologically complete drinking water. Their advantage lies in autonomous operation without the constant presence of servicing personnel. This is achieved by replacing filters and maintenance tasks carried out on a time-based logic basis. However, time-based logic does not account for actual volumes of purified water, leading to over expenditure on servicing some machines and untimely maintenance, resulting in a deterioration of water quality for others. This study investigates the impact of digitalization on optimizing service costs and the cost price of water purification. It is shown that through digitalization, the maintenance logic was changed to volume-based, resulting in reduced expenses on replacement filters (51%), servicing (13%), and collection (17%). Collectively, these factors reduced the cost of water by 20%. The decrease in cost enhances the profitability of the vending machine network. With a fixed water price, this is the only way to increase profitability and attract investors, consequently popularizing water vending machines. Subsequent research will focus on seeking alternative filters, materials, and water preparation technologies to achieve even greater machine autonomy. By assessing the established impact of digitalization on water vending machine operations, a predictive cost of water is calculated, assuming compliance with all operational requirements. The predicted cost reduction amounts to 39%, providing economic justification for future research endeavors.
Microscopic Evolution of the Pomadasys jubelini Testis from the Ivorian Continental Shelf
Authors: Kouassi Komenan Daouda , Konate Fahadama , Gnonsoakala Yoe Emmanuel , Mahn Yoro Camille , Jacques Miessan Jean- , D’almeida Marie-Anne
Published: November 2024

Undernourishment due to insufficient animal protein is rife in Africa. Fish consumption appears to be the solution to this problem. However, fish products are becoming increasingly scarce due to the depletion of fish farming resources in maritime and continental waters. Hence the need to intensify fish farming. This requires mastery of the reproduction of the fish to be domesticated particularly Pomadasys jubelini. Once the fish had been dissected, standard histological techniques were applied to the testicles taken from them. Microscopic study revealed that each testicle lobe is made up of several lobules. Each contained several cysts. Each cyst contained several germ cells of the same generation. Sex cell differentiation proceeded from the periphery to the spermiduct. Stage 4 individuals corresponded to the stage of sexual maturity.
Characterization of Geomagnetic Signatures and their Mineralization Potential in the Agnibilekrou Department (Eastern Cote d’Ivoire)
Authors: Florentin Tani Kouadio , Parfait Sombo Abé , Roger Assie Konan
Published: November 2024

The characterization of geomagnetic signatures conducted in the Agnibilékrou department (Eastern Côte d’Ivoire) highlights several magnetic anomalies indicating strong mineralization potential. Five aeromagnetic maps (Abengourou 4c and 4d, and Agnibilékrou 1b, 2a, and 2b) were used. These maps, derived from aerial surveys carried out by Kenting Earth Sciences Ltd between 1974 and 1976, were processed using filtering techniques (Butterworth filter, tilt angle filter, and vertical integration filter) to enhance the detection of magnetic anomalies in the subsurface. The magnetic anomalies, referred to as A1 and A2, are consistently observed across the maps and follow a NE-SW orientation, indicating the presence of basic and ultrabasic rocks rich in magnetite, often associated with metal deposits such as iron, nickel, or sulfides containing copper and cobalt. Additionally, sedimentary formations derived from the breakdown of granites, containing magnetite, may contribute to hydrothermal alteration processes, facilitating the formation of gold or polymetallic deposits. The left-lateral faults F1, F2, and F3, identified through distortions in the magnetic field on the maps, could act as circulation channels for hydrothermal fluids, known for transporting and depositing metals. In particular, the right-lateral fault F, which has undergone tectonic reactivation, appears to favor the concentration of metals. The NE-SW orientation of anomalies and fractures aligns with zones prone to hydrothermal alteration, a key process in the formation of gold and sulfide deposits. Finally, some surface-level anomalies, such as A3, highlighted by the tilt angle filter, represent easily accessible targets for mining exploration. This study, therefore, reveals significant mining potential in the area, especially for iron, nickel, and gold, driven by the combination of tectonic structures, magnetized rocks, and hydrothermal processes.
Constraints Related to Community Resilience to Climate-Sensitive Diseases in the Lower Ouémé Valley in Benin
Authors: D. Gnanvi Appolinaire , Mehinto Michel
Published: November 2024

Climate change negatively impacts the health of populations in the lower Ouémé valley. These effects on natural and physical systems affect vulnerable people and expose them more to the risks of malnutrition, vector-borne, non-communicable, food-borne or water-borne diseases and zoonoses. Faced with climate-sensitive diseases, what are the constraints that limit the control of infectious risks in hospitals? This research, which is part of the sociology of health, aims to contribute to improving the resilience of vulnerable local communities in the Adjohoun, Bonou and Dangbo health zones to malaria, cardiovascular diseases and acute respiratory infections. The methodological approach is based on quantitative data and discourse analysis to identify the organizational and technical capacities of hospitals and health centers. A total of 93 actors were approached in 03 municipalities at a rate of 31 people taken at random in each municipality. After triangulation of sources, the results show that the integration of climate information into disease surveillance makes the health early warning system effective. Then, strengthening the operational capacities of health personnel to ensure the resilience of populations to climate risks is essential. Finally, improving the technical capacity of health centers through the provision of sustainable equipment and technologies adapted to climate change is a way to meet new health challenges.
Erythrocytes Contribute to the Immunometabolic Cross-Talk
Authors: Papadopoulos Charalampos , Tentes Ioannis , Anagnostopoulos Konstantinos
Published: November 2024

Erythrocytes (red blood cells) interact with both the immune and the metabolic systems. However, emerging data indicate that they can also function as mediators in immunometabolic interactions. High-fat diet results in increased erythrocyte cholesterol, externalized phosphatidylserine, bound MCP1, myeloperoxidase and the generation of reactive oxygen species. As a result, a pro-inflammatory effect of the erythrocyte ensues subsequently triggering macrophage inflammation, chemotaxis, erythrophagocytosis and endothelial activation. Furthermore, as a consequence of metabolic syndrome or obesity, important immunoregulatory molecules of erythrocytes, such as CD47, Glycophorin A and microvesicles are affected. Finally, inflammation-induced lipid remodelling of erythrocytes possibly partakes in a positive feedback loop with inflammation. These studies strongly indicate that erythrocytes contribute to the immunometabolic cross-talk, mainly by linking the systemic metabolic status with innate immunity and inflammation. Further exploration of the implicated mechanisms could lead to potent therapeutic targets for metaflammation-related diseases.
Consistent, Inclusive Emissions Accounting Identifies Agriculture as the Leading Cause of Climate Change
Authors: Wedderburn-Bisshop Gerard
Published: November 2024

Recent advances in emissions accounting present a new understanding of climate change drivers. These advances are unconventional but promise a more consistent and inclusive accounting of greenhouse gases. We apply these advances, namely: consistent gross accounting of CO2 sources; linking land use emissions with sectors; using Effective Radiative Forcing (ERF) rather than Global Warming Potentials (GWPs) to compare emissions; and inclusive accounting of heating and cooling emissions. This approach boosts perceived carbon emissions from deforestation, and finds agriculture, the most extensive land user, to be the leading emissions sector and to have caused 60% (44%-86%) of global surface air temperature (GSAT) change from 1750 to 2020. We also find that fossil fuels are responsible for 23% of warming, a reduced contribution due to masking from cooling co-emissions. We test the validity of this accounting and find it useful for determining sector responsibility for present-day warming and for framing policy response, while recognising the dangers of assigning value to cooling emissions, due to health impacts and future warming.
Generative AI in Medicine and Healthcare: Moving Beyond the ‘Peak of Inflated Expectations’
Authors: Zhang Peng , Shi Jiayu , Kamel Boulos Maged N.
Published: November 2024

The rapid development of specific-purpose Large Language Models (LLMs), such as Med-PaLM, MEDITRON-70B, and Med-Gemini, has significantly impacted healthcare, offering unprecedented capabilities in clinical decision support, diagnostics, and personalized health monitoring. This paper reviews the advancements in medicine-specific LLMs, the integration of Retrieval-Augmented Generation (RAG) and prompt engineering, and their applications in improving diagnostic accuracy and educational utility. Despite the potential, these technologies present challenges, including bias, hallucinations, and the need for robust safety protocols. The paper also discusses the regulatory and ethical considerations necessary for integrating these models into mainstream healthcare. By examining current studies and developments, this paper aims to provide a comprehensive overview of the state of LLMs in medicine and highlight the future directions for research and application. The study concludes that while LLMs hold immense potential, their safe and effective integration into clinical practice requires rigorous testing, ongoing evaluation, and continuous collaboration among stakeholders.