bluuebunny/crossref_metadata_2025 huggingface dataset:
Caracterização microbiológica de águas cinzas: eficiência de filtro com materiais não convencionais
Authors: Passos Erik Santos , Carvalho Roseanne Santos de , Brandão Louise Francisca Sampaio
Published: August 2021

A escassez da água é uma problemática pré-existente da sociedade pós-moderna e na atualidade ganhou destaque principalmente nas regiões que sempre desfrutaram de abundantes recursos hídricos e passaram a sofrer com a falta do bem natural. São inúmeros os motivos que levam à escassez da água, perpassando desde a má distribuição territorial até a contaminação dos mananciais. Sendo assim, são necessárias técnicas e soluções como a reutilização de águas cinzas ou aproveitamento de águas pluviais para utilização em fins menos nobres, como lavagem de pisos, calçadas, rega de jardins, descargas sanitárias e irrigação. Com o intuito de aliar o reaproveitamento de resíduos à reutilização de águas cinzas, o artigo teve como objetivo uma caracterização microbiológica de coliformes totais e coliformes termotolerantes de águas cinzas tratadas por meio de um filtro composto de esponjas usadas, resíduos da construção civil e antracito, avaliando a eficiência do tratamento e visando a possibilidades de reuso não potável. As amostras de águas cinzas foram coletadas de um banheiro feminino no Instituto Federal de Sergipe, Campus Aracaju, Estado de Sergipe, Nordeste do Brasil, onde foram analisadas antes e após a passagem no filtro. As análises após filtragem apontaram reduções médias de 93,14% na concentração de coliformes totais e de 90,42% de E. coli, caracterizando-o como um avanço para aliar o desenvolvimento à sustentabilidade.
Avaliação do desmatamento em Itaiópolis, Estado de Santa Catarina, Brasil, usando imagens RapidEye
Authors: Barros Lucas Vincent Lopes de
Published: August 2021

Através de imagens do satélite RapidEye, disponibilizadas pelo Ministério do Meio Ambiente, efetuou-se a classificação supervisionada para avaliar o progresso do desmatamento no Município de Itaiópolis, no Estado de Santa Catarina, Brasil, entre 2011 e 2013. A classificação foi pautada em seis classes de cobertura do solo, florestas nativas, florestas exóticas, lavouras, corpos hídricos, capoeirinhas e solo exposto. Como verdades terrestres, foram utilizados casos de perícia criminal atendidos pelo Instituto Geral de Perícias de Santa Catarina (IGP-SC) no período compreendido pela série, totalizando 27 casos de apuração de danos à flora. A série temporal obtida teve acurácia global variando de 54,46% (2013) a 65,83% (2012) e coeficientes Kappa entre 0,415 e 0,520, considerados de bom desempenho. De 2011 para 2013, 23,71% da cobertura florestal nativa foi suprimida no município. As áreas correspondentes foram convertidas em lavouras ou cultivo de espécies exóticas (Pinus elliottii e Eucalyptus globulus). Conclui-se que o uso de imagens do satélite RapidEye para avaliação da progressão do desmatamento é adequado e pode ser replicado para outras regiões.
Destinação de pás de turbinas eólicas instaladas no Estado da Bahia, Brasil
Authors: Ramos Júnior Mário Joel , Almeida Edna dos Santos
Published: August 2021

O Estado da Bahia ocupa o primeiro lugar em geração de energia eólica no Brasil. Em outubro de 2020, a Bahia tinha 177 parques eólicos em operação com capacidade instalada de 4.406 MW e geração de 1,95 TW/h. O crescimento da energia eólica na Bahia trouxe diversos benefícios, a exemplo de diversificação da matriz energética do estado, da segurança energética e da atração de investimentos, bem como desafios relacionados à destinação dos componentes, como as pás eólicas, após o período de vida útil. Estas pás das turbinas eólicas são construídas com materiais compósitos, tendo como base fibra de vidro ou fibra de carbono. Neste contexto, o objetivo deste trabalho é avaliar quais são as opções e os desafios para a destinação ambientalmente correta das pás eólicas utilizadas nos parques eólicos localizados na Bahia, após o final da vida útil. Em outros países, o descarte em aterros ou incineração em plantas de processamento de resíduos têm sido o tratamento mais comum para as pás eólicas das turbinas eólicas após o final da vida útil. Entretanto, foi identificado que a reciclagem de materiais compósitos é uma indústria em fase embrionária que pode beneficiar não somente a indústria eólica, mas também outras indústrias, tais como a automotiva. Através do desenvolvimento de pesquisa no estado, sugere-se que a Bahia tenha um centro de reciclagem de materiais compósitos que poderá atender a todo o país.
Antineoplastic agents associated with the development of drug-induced pancreatitis
Authors: Arablinskiy N. A. , Ostroumova O. D. , Filippova A. V.
Published: August 2021

The frequency of drug-induced pancreatitis (LIP) is from 2 to 5% of all cases of acute pancreatitis (OP), but it is much more common in risk groups – among children and HIV-infected patients. The use of a number of drugs (drugs) is associated with the development of lipids, among them a special place is occupied by antitumor drugs due to the great medical and social significance of oncological diseases and the appearance in recent years of a large number of new antitumor drugs. The purpose of this review was to review the literature data on antitumor drugs, the use of which is associated with the development of lipids. LI OP developed in 1.8% of patients treated with nivolumab or pembroluzumab. In total, in 14 phase 1-3 studies on the efficacy and safety of ipilimumab, the development of OP was reported in less than 1% of the subjects. Therapy with molecular-targeted targeted drugs, such as tyrosine kinase inhibitors (TKI) or other representatives of the kinase inhibitor class, is also associated with the development of OP. The HP database of the World Health Organization (WHO, World Health Organization Adverse Drug Reaction database) contains reports of individual clinical cases of OP development during treatment with proteosome inhibitors and antibody-drug conjugates. It is known that the following antitumor drugs are also associated with the development of pancreatitis: 6-mercaptopurine, L-asparaginase, tamoxifen, cisplatin, cytarabine, ifosfamide, paclitaxel, docetaxel, oxaliplatin, capecitabine, periwinkle alkaloids, cytosine, cisplatin, interferon alpha-2b, doxorubicin, tamoxifen, gefitinib, vinorelbine, levamizole, methotrexate, 5-fluorouracil, capecitabine, trans-retinoic acid.
Case report of partial response on second line with Ramucirumab and FOLFIRI in treatment of 74 year old male with metastatic HER2-negative gastric adenocarcinoma
Authors: Besova N. S. , Titova T. A. , Kalinin A. E. , Shalenkov V. A. , Stilidi I. S.
Published: August 2021

According to the data of the world statistics, gastric cancer (GC) occupies the 5th place by morbidity and the 3rd one by mortality among malignant neoplasms. A significant proportion of patients are elderly patients, the proportion of which in real clinical practice can reach up to 60%. Ramucirumab is among the standards of second-line drug therapy both in monotherapy and in combination with paclitaxel. The feasibility of prescribing ramucirumab to patients with disseminated cancer of the elderly and its satisfactory tolerability is shown in a subgroup analysis of the REGARD and RAINBOW studies. The use of paclitaxel, included in the standard first-line regimens, may be limited by persistent neurotoxicity, a side effect of platinum derivatives. In this regard, the effectiveness of the combination of ramucirumab with the FOLFIRI regimen as a second-line therapy began to be studied. The article presents a clinical case of achieving a partial effect on the second-line therapy with ramucirumab with FOLFIRI regimen in a 74-year-old patient with HER2-negative gastric adenocarcinoma while registering rapid progression after 4 courses of first-line chemotherapy in XELOX regimen. Tolerability of the second line was acceptable: asthenia grade 1, stomatitis grade 1-2, neutropenia grade 3 were observed, so the irinotecan dose was reduced to 165 mg/m2. By June 2021, there were 10 28-day cycles of treatment, which is ongoing. The duration of disease control in the second line therapy was 11+ months, of which 9+ months – on the background of FOLFIRI regimen drug therapy with ramucirumab.
Mechanisms of metastasis and development of resistance to therapy in breast cancer. A clinical case of the effectiveness of ixabepilone in hormone-receptorpositive breast cancer with multidrug resistance
Authors: Stukan A. I. , Goryainova A. Y. , Sharov S. V. , Andreev D. V. , Lymar E. V.
Published: August 2021

Metastatic breast cancer occupies a leading position in the structure of mortality among women with oncological diseases worldwide. At the same time, the control of metastatic disease remains a significant problem for clinical oncology despite the improvement of early screening indicators, as well as the introduction of targeted therapy in clinical practice. An increase in the tumor stemness and the epithelial-mesenchymal transition in the primary tumor leads to the plasticity of the tumor cell. This is realized in the progression of the disease, resistance to the therapy and the appearance of distant metastases. Numerous signaling pathways, including PI3K/APK, STAT3, Wnt, Hedgehog, and Notch, play a key role in maintaining cellular plasticity in breast cancer. Understanding the cellular mechanisms of breast cancer cell plasticity with the development of multidrug resistance is a prerequisite for the development of effective therapeutic strategies against metastatic breast cancer in late-line therapy. The article presents an overview of the current understanding of the biological mechanism of the metastatic cascade and resistance to therapy. It is from the point of view of the plasticity of the tumor cell and the increase in the stemness of the tumor that the resistance to treatment is considered. The effectiveness of the representative of Ixabepilone was analyzed in the case of its use in the late-line therapy of hormone-receptor-positive breast cancer with multidrug resistance.
Clinical case of the use of oral metronomic vinorelbin in patient with metastatic Her2 negative breast cancer
Authors: Frolova M. A. , Glazkova E. V. , Stenina M. B.
Published: August 2021

Endocrine therapy in combination with inhibitors of cyclin-dependent kinases 4/6 in first lines is the current standard of treatment of metastatic ER positive Her2 negative breast cancer. After progression on several lines of endocrine therapy according to current principles we apply sequential lines of monochemotherapy. If possible non-toxic agents are prefered in order to maintain high quality of life. The special role in this context may play oral agents, when regular visits in clinic and intravenous injection are not needed. The efficacy of oral vinorelbine is well explored, unfortunately the standard dosage regimen сan have quite high especially hematologic toxicity. The metronomic dosing regimen is believed to be as effective as the standard, but is less toxic. In addition, the anti-angiogenic properties of the metronomic mode are described. Taking into account the increasing use of combination of endocrine therapy with CDK4/6 inhibitors in first treatment lines, it is extremely important to study the efficacy and tolerability of various regimens and drugs after progression on combined endocrine therapy. In this article, we represent a clinical case of the use of oral vinorelbine in the metronomic mode in the patient after progression on combination of fulvestrant and palbociclib. Long-term disease control with satisfactory quality of life has been demonstrated.
Experience of treatment of a patient with non-small cell lung cancer with met exon 14 skipping
Authors: Mandrina M. O. , Breder V. V. , Ivanov M. V. , Lebedeva A. A. , Gorbatsevich V. V. , Laktionov K. K. , Kononets P. V.
Published: August 2021

Personalized therapy is starting to play an increasing role in modern approaches to the treatment of oncological diseases. The previously existing uniform standard for each malignant disease is expanded with new options and treatment possibilities, depending on each specific clinical situation. That increases the  effectiveness of  therapy and helps to control the  disease. A  separate niche in the individual approach to anti-tumor treatment is occupied by targeted therapy of malignancies. There are a lot of mutations that can lead to the emergence of malignant neoplasms. So of all that multitude of choices the individual approach to a patient helps to select the mutations that are most likely to be found in a given patient. The research in the area of the c-MET mutation has allowed it to occupy its niche as a therapeutic target. The identification of this mutation is not included in the routine set of analyses performed for a patient with diagnosed lung adenocarcinoma. But expanding the panel of molecular testing would increase the detectability of this mutation and, as a result, improve the quality of treatment for this category of patients. This clinical case describes the experience of treatment of an elderly patient with lung adenocarcinoma, in whose tumor tissue a MET mutation was detected.
Immunotherapy in elderly patients
Authors: Lyadova M. A. , Lyadov V. K.
Published: August 2021

In the recent years the growing life expectancy of the population and increasing cancer burden in elderly patients substantiate the urgent need for the search of optimal cancer treatment strategies. This article provides an overview of the current literature on the efficacy and safety of checkpoint inhibitors in the elderly population. A literature search for published studies using Medline (PubMed) and Elibrary databases was performed. All studies containing data on treatment results including tumor response criteria, treatment response rate, tumor control rate, overall survival were included. Case studies, animal studies and studies containing duplicate results were excluded from the analysis. In elderly patients with cancer there is a substantial number of comorbid conditions and functional disorders, which may decrease the efficacy and modulate the tolerability of immune checkpoint inhibitors (ICI). Besides, different changes associated with immunologic ageing, including thymolysis, increase of the number of memory B-cells and a decrease of hematopoesis intensity are observed. Several studies performed a comparative analysis of efficacy and toxicity of ICIs in elderly and younger patients. In most cases similar results for efficacy and toxicity were demonstrated. To evaluate the toxicity and the influence of treatment on functional status and other important measures in geriatric population further studies of factors, influencing the tolerability and treatment response of newer ICI in elderly cancer patients are needed, including additional adverse events associated with treatment.
Erlotinib: How to increase the duration of effective use of tyrosine kinase inhibitors in non-small cell lung cancer with EGFR mutation
Authors: Borisova E. I. , Gutorov S. L.
Published: August 2021

Tyrosine kinase inhibitors of the first, second and third generations are the main treatment method for non-small cell lung cancer with EGFR mutation. About 60% of patients progressing on a first-generation or second-generation tyrosine kinase inhibitor acquire T790M mutation. An alternative is first-line osimertinib, but second-line treatment options are limited, and therefore it is important to find a strategy that allows to extend the effective treatment of TKI. One of the rational approaches is the use of a combination of a first-generation tyrosine kinase inhibitor with anti-VEGF agents. The available information sources show an increase in the effectiveness of the combined use of erlotinib and antiangiogenic drugs-bevacizumab and ramucirumab. The combination of erlotinib and bevacizumab in several studies of the second — third phase, led to a statistically significant increase in progression-free survival, but did not show a significant increase in overall survival. In the Phase 3 RELAY study, the combination of erlotinib and ramucirumab showed comparable efficacy with the third-generation TKI — osimertinib in the first line, however, overall survival results are not yet available. At the same time, there are more opportunities to choose the secondline mode, taking into account the known frequency of detection of the T790M mutation. The optimal treatment sequence is discussed, with the option of prescribing a combination of erlotinib with bevacizumab or ramucirumab in the first line and osimertinib in the second in the presence of the T790M mutation. In such patients, osimertinib may be prescribed in the second line.
Biomarkers in metastatic melanoma of the skin: can we more accurately choose the tactics of treating our patients?
Authors: Zaretsky A. R. , Demidov L. V. , Samoylenko I. V.
Published: August 2021

With an increasing number of alternative effective therapies available for patients, there is an increasing need for a more accurate selection for therapy (compared to observation, for example, after radical surgical treatment), selection of the optimal therapy (prediction of primary resistance or, conversely, high sensitivity), and criteria for stopping treatment (complete tumor elimination) or changing therapy (molecular, i.e. preclinical and preradiological progression). We look for answers to all these questions in a variety of biomarkers. Many clinical markers (e.g. ECOG performance status or disease prevalence), molecular genetic (e.g. such as mutations in the BRAF gene, NRAS, NF1, TMB), immunological (e.g. tumor infiltration by lymphocytes and expression of PDl1, PDl2, PD1 or other «immune checkpoints» on tumor cells and microenvironmental cells), as well as factors circulating in the blood and plasma (e.g., blood cell-to-cell ratio, circulating tumor DNA or cytokines in the peripheral blood). In this study, we have tried to analyze the data accumulated so far and attempt to relate them both to current clinical practice and available therapies, as well as to outline the prospects for upcoming research in this area. In our opinion, the available data may influence the current routine practice of oncologists and allow for a more careful choice of first-line therapy to maximize benefit and minimize harm. Although it is likely that some organizational effort will be needed to change established clinical practice in order to identify such biomarkers.
The role of immunotherapy in the management of metastatic/recurrent female reproductive system neoplasms
Authors: Rumyantsev A. A. , Anokhin A. Yu.
Published: August 2021

In 2019 malignant neoplasms of the female reproductive system (ovarian cancer, (OC), endometrial carcinoma (EC) and cervical cancer (CC) were diagnosed in 58 860 patients – 17.6% of all malignant tumors in women in Russia. The morbidity and mortality rates from these neoplasms remain high over the past 10 years. This article provides a detailed review of the current evidence base for  the  use of  various immunotherapeutic agents in  mentioned malignant neoplasms. It has been demonstrated that in  relapsed OC (ROC), the  only proved indication for  immunotherapy is tumors with microsatellite instability (MSI), whereas PD-L1 does not have an independent role in this disease. MSI occurs in approximately 8% of patients with metastatic OC. A significantly higher frequency MSI — up to 25% is detected in metastatic EC. MSI-positive subtype of the disease is characterized by an extremely high sensitivity to immunotherapy - the  rate of  objective response with pembrolizumab exceeds 50%. For  MS-stable  EC, the  combination of  pembrolizumab and lenvatinib is an effective therapeutic option. In  advanced CC, on the other hand, PD-L1 has a predictive role for immunotherapy efficacy — the KEYNOTE-158 study showed that about 15% of  patients with extensively pretreated metastatic PD-L1-positive CC can achieve long-term remission with pembrolizumab compared to 0% in PD-L1 negative tumors. Current evidence shows that PD-L1 expression can be observed in ≥ 30% of patients.
Асоцијативни речници као извор за истраживање транзиционих промена у руском и српском друштву краја ХХ и почетка ХХI века
Authors: Koncarevic Ksenija J. , Vasovic Jelena B.
Published: August 2021

У раду се, на материјалу асоцијативних речника, спроводи анализа садржине и структуре асоцијативних поља одабраних лексема из семантичког поља „политика, економија, друштвени односи” у руском и српском језику са циљем реконструисања представа о транзиционим променама у друштву и њиховом одразу у свести носилаца двају језика. Добијени резултати доводе се у корелацију са новијим социолошким студијама о транзицији у српском и руском друштву.
О конгруенцији староруских збирних именица у Повести о минулим временима
Authors: Visnjevac Visnja B.
Published: August 2021

У раду се на материјалу староруског споменика Повест о минулим временима разматра конгруенција збирних именица братиꙗ, дрѹжина, Рѹсь и родъ са заменицама, глаголима, партиципима, посесивима и придевима. Таква конгруенција могла је бити семантичка − када је реч уз коју збирна именица стоји у форми множине, или формалнограматичка − када је одговарајућа реч у форми једнине. Истовремено се врши поређење са српским језиком и разматра конгруенција у оквиру одговарајућих преводних еквивалената.
Формална обележја компаративних фразеологизама у средњевисоконемачком језику
Authors: Ivanovic Branislav D.
Published: August 2021

Фразеологија средњевисоконемачког језика и данас се сматра недовољно истраженом облашћу германистичке лингвистике. Доскорашњи недостатак савременог фразеолошког речника за наведени период, хетероген текстуални корпус ове епохе и непостојање чвршће везе између фразеологије и историје немачког језика само су неки од разлога за наведено стање. У фокусу истраживања фразеологије ранијих периода превасходно су се налазиле одређене супкласе, и то пословице, крилатице и геминатни фразеологизми, а током последње деценије интересовање истраживача окреће се осталим слабије проученим фразеолошким супкласама, пре свега различитим типовима идиома и колокација. У раду се на основу примера из корпуса утврђују формална обележја средњевисоконемачких компаративних фразеологизама из синхронијске перспективе. Наведена тема је од значаја за дијахронијску фразеологију с обзиром на то да дефинисана структурна обележја у системском смислу представљају предуслов за даља истраживања дијахронијских процеса примарне и секундарне фразеологизације код компаративних фразеологизама у млађим епохама, а захваљујући установљеним формалним обележјима могу се доносити нови закључци о питањима дијахронијских промена код ове супкласе, чиме се стиче увид и у шире процесе дијахронијског динамизма немачког фразеолексикона од средњевисоконемачког до савременог језичког стања. Јасно установљена формална обележја могу додатно да послуже и као један од индикатора за препознавање ових лексикализованих структура у средњевисоконемачком тексту. На основу анализе одабраних примера може се закључити да средњевисоконемачки компаративни фразеологизми превасходно представљају бицентричне структуре испод нивоа реченице, које чувају конзервативно стање када су у питању компаративне партикуле, а истовремено не показују редупликацију еквативних партикула. Именичка компонента у оквиру secundum-a показује средњевисоконемачке језичке иновације у смислу све чвршћег етаблирања левог поља номиналне фразе. У свом основном облику могу да имају и инверзију primum-a и secundum-а, а известан број компаративних фразеологизама може да показује и одређене фонетске специфичности, што иде у прилог конвергентнијем међуодносу између различитих фразеолошких супкласа у старијим језичким периодима.
Поетички феномени књижевног опуса Десанке Максимовић
Authors: Materic Aleksandar M.
Published: August 2021

Тутњевић, Станиша (2020), Лирска мисаоност Десанке Максимовић, Београд: Свет књиге; Десанка Максимовић: Тражим помиловање, приредио Станиша Тутњевић, Београд: Свет књиге.
Pengembangan media pembelajaran tajwid berbasis aplikasi Android
Authors: Nadawiyyah Hilyatun , Anggraeni Dewi
Published: August 2021

Penelitian ini bertujuan untuk: 1.) Menganalisis kebutuhan pengembangan aplikasi android pada mata pelajaran Pendidikan Agama Islam materi tajwid; 2.) Mendesain aplikasi android pada mata pelajaran Pendidikan Agama Islam materi tajwid; 3.) Menganalisis pengembangan aplikasi android pada mata pelajaran Pendidikan Agama Islam materi tajwid; 4.) Menganalisis implementasi aplikasi android pada mata pelajaran Pendidikan Agama Islam materi tajwid; dan 5.) Menganalisis evaluasi aplikasi android pada mata pelajaran Pendidikan Agama Islam materi tajwid. Model penelitian dan pengembangan yang digunakan yaitu model pengembangan ADDIE. Hasil penelitian ini menunjukan bahwa berdasarkan analisis kebutuhan peserta didik, kurikulum, materi dan media, desain media berdasarkan pada penyesuaian dengan karakteristik peserta didik dan berdasarkan pada materi yang dipelajari, pengembangan media berdasarkan pada uji validitas yang dilakukan dengan ahli media dan ahli materi, implementasi berdasarkan uji coba terhadap guru dan peserta didik, evaluasi berdasarkan pada evaluasi formatif dan sumatif menunjukkan bahwa penggunaan media pembelajaran tajwid berbasis aplikasi android sangat layak digunakan sebagai media pendukung pada pembelajaran PAI materi tajwid. Development of Tajwid learning media based on Android applicationAbstractThis study aims to: 1.) Analyze the needs of developing android applications on Islamic Religious Education subjects recitation; 2.) Designing android applications on Islamic Religious Education subjects recitation; 3.) Analyzing the development of android applications on Islamic Religious Education subjects Tajweed; 4.) Analyze the implementation of Android applications on Islamic Religious Education subjects Tajweed material; and 5.) Analyze the evaluation of Android applications on Islamic Religious Education subjects Tajweed material. The research and development model used is the ADDIE development model. The results of this study indicate that based on the analysis of student needs, curriculum, materials, and media, media design is based on adjustments to the characteristics of students and based on the material being studied, media development is based on validity tests conducted with media experts and material experts, implementation is based on trials on teachers and students, evaluation based on formative and summative evaluations shows that the use of Tajweed learning media based on Android applications is very feasible to be used as a supporting medium in the learning of Tajweed Tajweed material.
Peningkatan model SAMR serta penerapannya untuk pembelajaran online yang mendalam
Authors: Alfiana Herlia
Published: August 2021

Pelaksanaan e-learning menjadi desakan solusi untuk dapat menyampaikan pembelajaran di tengah pandemi. Pelaksanaan e-learning sangat mengandalkan pemanfaatan teknologi. Hal ini menjadi tantangan baru karena ketidaksiapan pendidik karena keterbatasan literasi digital dan sulitnya menentukan teknologi yang akan digunakan dalam pembelajaran.  Untuk mengatasi permasalahan tersebut, penerapan model SAMR (Substitution, Augmentation, Modification, Redefinition) menjadi sebuah solusi. Model SAMR banyak diterapkan oleh praktisi pendidikan karena jelas, sederhana, dan mudah diadaptasi. Namun, model SAMR memiliki tiga kritik untuk peningkatan. Penelitian ini merupakan penelitian literature review yang menggunakan metode PRISMA systematic review. Kajian pada penelitian ini menjawab tantangan perbaikan pada penerapan model SAMR dalam pembelajaran dan mengkaji kesesuaian model SAMR untuk diterapkan pada e-learning yang syarat akan pemanfaatan teknologi dan bagaimana mewujudkan e-learning yang mendalam.SAMR model improvement challenge and application for deeper online learningAbstractE-learning becomes an urgent solution to be able to deliver learning in the midst of a pandemic. The implementation of e-learning relies heavily on technology integration. This is a new challenge for educators due to the unpreparedness, the limitations of digital literacy, and the difficulty in determining the appropriate technology in e-learning. In order to overcome these problems, the application of the SAMR model (Substitution, Augmentation, Modification, Redefinition) is one of the solutions. Education practitioners have widely applied the SAMR model because of its clarity, simplicity, easiness, and adaptability. However, the SAMR model has three drawbacks that can be improved. This study answers the challenge in improving the application of the SAMR model in learning and assessing the suitability of the SAMR model applied to e-learning which requires technology.
Pengembangan media video berbasis discovery learning untuk siswa sekolah dasar
Authors: Ulya Farihah Inayatul , Sumarno Sumarno , Wijayanti Arfilia
Published: August 2021

Penelitian ini bertujuan untuk mengetahui kevalidan, kepraktisan, dan keefektifan media video berbasis model discovery learning. Metode dalam penelitian ini adalah Research and Development (R&D) dengan model ADDIE (Analysis, Design, Development, Implementation, and Evaluation). Subjek dalam penelitian ini terdiri dari 3 ahli media, 3 ahli materi, guru dan 24 siswa kelas 3 SD Negeri Mojoagung 01 Pati tahun pelajaran 2020/2021. Metode pengumpulan data terdiri dari observasi, wawancara, dokumentasi, kuesioner, posttest, dan kinerja dengan teknik analisis data kualitatif dan kuantitatif. Hasil review ahli media menunjukkan hasil persentase sebesar 92% (sangat baik), ahli materi 95% (sangat baik), kuesioner guru 97% (sangat baik), kuesioner siswa 99% (sangat baik), posttest berupa soal uraian ( 3 muatan pembelajaran yaitu 3 soal bahasa indonesis, 4 soal matematika, 3 soal SBdP), dan kinerja dari 24 siswa 100% siswa mencapai nilai diatas KKM ≥ 65. Berdasarkan hasil analisis, media video berbasis model discovery learning valid, praktis, dan efektif digunakan pada tema 6 energi dan perubahannya subtema 1 sumber energi pembelajaran 3.Discovery learning-based video media development for elementary school studentsAbstractThis study aims to know video media's validity, practicality, and effectiveness based on discovery learning models. This research applies the research and development (R&D) method with the ADDIE model (Analysis, Design, Development, Implementation, and Evaluation). The subjects in this study consisted of 3 media experts, three material experts, teachers, and 24 3rd grade students of Elementary School 01 Pati. The data collection methods were observation, interviews, documentation, questionnaire, post-test, and performance with qualitative and quantitative data analysis techniques. The results of the media expert review show the percentage results of (92%), material expert (95%), teacher questionnaire (97%), student questionnaire (99%), post-test in the form of description questions (3 learning contents, namely 3 Indonesian language questions, four maths questions, 3 SBdP questions), and performance of 24 students (100%) students achieve scores above the KKM 65. Based on the analysis results, the video media based on the discovery learning model is valid, practical, and effectively used on theme six energy. The changes are sub-theme 1 learning energy source 3.
Detecting abnormal electricity usage using unsupervised learning model in unlabeled data
Authors:   Faculty of Engineering and Technology, Multimedia University, Melaka, Malaysia, et al. Jesmeen
Published: August 2021

Smart-home systems achieved great popularity in the last decade as they increase the comfort and quality of life. Reduction of energy consumption became a very important desiderate in the context of the explosive technological development of modern society with a major impact on the future development of mankind. Moreover, due to the large amount of data available from smart meters installed in households. It makes leverage to able to find data abnormalities for better monitoring and forecasting. Detecting data anomalies helps in making a better decision for reducing energy usage wasted. In recent years, machine learning models are widely used for developing intelligent systems. Currently, researchers’ main focus is on developing supervised learning models for predicting anomalies. However, there are challenges to train models with unlabeled data indicating data anomaly or not. In this paper, abnormalities are detected in electricity usage using unsupervised learning and evaluated using Excess Mass. The unsupervised anomaly detection model is based on Gaussian Mixture Model (GMM) and Isolation Forest (iForest). The models are compared with Local Outlier Factor (LOF) and One-class support vector machine (OCSVM). The proposed framework is tested with actual electricity usage and temperature data obtained from Numenta Anomaly Benchmark (NAB), which contains normal and anomaly data in time series. Finally, it has been observed that the iForest out-performed as the detection model for the selected use case. The outcome showed that the iForest can quickly detect anomalies in electricity usage data with only a sequence of data without feature extraction. The proposed model is suitable for the Smart Home Energy Management System's practical requirement and can be implemented in various houses independently. The proposed system can also be extended with the various use cases having similar data types.
Точная модель самокаталитического роста нитевидных нанокристаллов Ga(As, P)
Authors: Сибирев Н.В. , Бердников Ю.С. , Федоров В.В. , Штром И.В. , Большаков А.Д.
Published: August 2021

Предложена модель для расчета состава самокаталитических нитевидных нанокристаллов, не содержащая подгоночных параметров. Показано, что состав нитевидных нанокристаллов Ga(As, P) не зависит от скорости роста при фиксированном отношении суммарных потоков атомов V и III групп. Результаты моделирования хорошо согласуются с экспериментально наблюдаемой зависимостью состава нитевидных нанокристаллов от соотношения потоков атомов As и P. Ключевые слова: нитевидные нанокристаллы Ga(As,P), молекулярно-пучковая эпитаксия, самокаталитический рост, количественный расчет состава.
Квантово-каскадный лазер на 3.3 ТГц на основе активного модуля из трех квантовых ям GaAs/AlGaAs с рабочей температурой >120 K
Authors: Хабибуллин Р.А. , Маремьянин К.В. , Пономарев Д.С. , Галиев Р.Р. , Зайцев А.А. , Данилов А.И. , Васильевский И.С. , Виниченко А.Н. , Клочков А.Н. , Афоненко А.А. , Ушаков Д.В. , Морозов С.В. , Гавриленко В.И.
Published: August 2021

In this work, we have optimized the THz QCL design with an active module based on three GaAs/Al0.18Ga0.82As quantum wells for high-temperature generation at a frequency of about 3.3 THz. A heterostructure based on the developed design with an active region thickness of 10 μm was grown by molecular beam epitaxy with a deviation of the active module thickness from the nominal less than 1%. The fabricated THz QCLs with a double metal waveguide demonstrate lasing up to a temperature of 125 K. Investigations of the I–V characteristics, the dependences of the integrated radiation on the current and the lasing spectra showed good agreement with the calculated characteristics.
Химически осажденные пленки сульфида свинца, легированные кобальтом
Authors: Маскаева Л.Н. , Мостовщикова Е.В. , Марков В.Ф. , Воронин В.И. , Поздин А.В. , Селянин И.О. , Михайлова А.И.
Published: August 2021

В настоящей работе, являющейся продолжением исследований по легированию химически осажденных слоев PbS(I), обсуждается влияние ионов кобальта на их морфологические, структурные, оптические и фотоэлектрические свойства. Элементным энергодисперсионным анализом показано, что кобальт обнаруживается в пленках при концентрации его хлорида в реакционной смеси ≥0.04 моль/л. Полученные пленки PbS(I, Co) сохраняют кубическую B1 структуру (пр. гр. Fm3m). Установлена тенденция повышения ширины запрещенной зоны пленок PbS(I, Co) от 0.57 до 0.75 эВ с ростом в них содержания наночастиц с 1 до ~8% при 1.5-часовом осаждении и от 0.57 до 0.68 эВ --- с 13 до ~28% при 3-часовом процессе. На концентрационной зависимости вольтовой чувствительности пленок PbS(I, Co), осажденных в течение 1.5 ч, наблюдаются два максимума, соответствующие 1 и 4% содержанию в них наночастиц. При трехчасовом процессе синтеза отмечено резкое снижение фотоответа с увеличением содержания частиц нанодиапазона до ~13-28% в слоях PbS(I, Co). Показано, что плотность фототока снижается с увеличением содержания наночастиц в пленках в ряду PbS(Сo) -> PbS->PbS(I, Сo)->PbS(I). Ключевые слова: сульфид свинца, химическое осаждение, легирование кобальтом, морфология пленок, структурные свойства, ширина запрещенной зоны, вольтовая и токовая фоточувствительность.
Система локализованных экситонов на кислородных комплексах в CdS
Authors: Морозова Н.К. , Мирошникова И.Н.
Published: August 2021

Intense CdS luminescence in the blue and green spectral regions is widely used in all areas of optoelectronics. In this spectrum band are working on lasers CdS. This paper presents the results of a study of the exciton region of the CdS spectrum based on the theory of anti-intersecting bands (bands anticrossing theory - BAC) with the involvement of broader initial data for the analysis of optical properties. Depending on the growth conditions of CdS, the presence and change in the oxygen concentration, as well as the equilibrium of intrinsic point defects, which determines the change in the composition of the crystals. The concept of the nonuniform distribution of isoelectronic centers in the bulk of CdS due to their predominant segregation on compensating stacking faults is introduced. Cathodoluminescence (CL) spectra were studied using various recording methods, excitation intensity and temperature, as well as pulsed CL at high excitation intensities. In a scanning electron microscope from local registration and a high excitation density, the emission of the edge luminescence components of CdS was detected at 300 K To analyze the optical data, we used the capabilities of the method for constructing band models based on the BAC theory, which. collects extensive and multilateral information about specific samples. A model of a CdS O multizone with stacking faults is presented, which determines the spectrum of edge emission. An explanation of the nature of the green edge emission of cadmium sulfide as excitons localized on oxygen-containing complexes in SF layers has been obtained for the first time. It was found that the system of levels of localized excitons at stacking faults does not change either with temperature up to 300 K, or with a change in the oxygen solubility in the crystal to the limiting one. It is shown that the presence of isoelectronic oxygen centers appear itself in the electro-physical properties of crystals. Recommendations are given for the diagnostics of crystals suitable for the creation of luminescent systems or lasers that are stable in operation.
Квантово-каскадный лазер с выводом излучения через текстурированный слой
Authors: Бабичев А.В , Колодезный Е.С , Гладышев А.Г , Денисов Д.В , Вознюк Г.В , Митрофанов М.И , Михайлов Д.А , Чистяков Д.В , Курицын Д.И , Дюделев В.В , Слипченко С.О , Лютецкий А.В , Евтихиев В.П , Карачинский Л.Я , Новиков И.И , Морозов С.В , Соколовский Г.С , Пихтин Н.А , Егоров А.Ю
Published: August 2021

The results of studies of ring quantum-cascade laser with a surface emission with radiation output through a textured layer formed in the layers of the top cladding of the waveguide by ultrahigh vacuum ion beam milling are presented. The far-field profile shows that the radiation is output through the windows with a textured layer in the range of angles of ~ 63–75 degrees to the normal.
Исследование методов текстурирования светодиодов на основе гетероструктур AlGaAs/GaAs
Authors: Малевская А.В. , Ильинская Н.Д. , Калюжный Н.А. , Малевский Д.А. , Задиранов Ю.М. , Покровский П.В. , Блохин А.А. , Андреева А.В.
Published: August 2021

Investigations of methods for texturing the light-emitting surface of IR light-emitting diodes (LEDs) (wavelength 850 nm) based on AlGaAs/GaAs heterostructures with Bragg reflectors have been carried out. Developed were methods of liquid and plasma-chemical etching of solid solution for creating peaks (pyramids) of different form, 0.2–1.5 µm height. Estimation of the effect of texturing methods and also configuration of peaks on the light-emitting diode electroluminescence intensity has been performed. The increase of the electroluminescence intensity by 25% has been achieved.
Фотоэлектрические преобразователи узкополосного излучения на основе гетероструктур InGaAsP/InP
Authors: Потапович Н.С. , Нахимович М.В. , Хвостиков В.П.
Published: August 2021

Utilizing performed research, photoelectric converters of narrow-band radiation (λ ≈ 1.0–1.3 µm) based on InGaAsP / InP heterostructures with an epitaxial p / n junction have been developed and created. Technological regimes that apply of for creating high-quality layers of quaternary InGaAsP solid solutions isoperiodic to indium phosphide in a wide range of compositions by liquid-phase epitaxy have been determined.
The effect of empathy to bystander's role towards bullying at school through moral disengagement as a mediator
Authors:   Department of Psychology, Faculty of Psychology and Socio-Cultural Sciences, Universitas Islam Indonesia, Yogyakarta 55584, Indonesia, Gholiyah Yayah Durrotul , Nashori H. Fuad , Diana Raden Rachmy ,   Department of Psychology, Faculty of Social Sciences and Humanities, Universitas Islam Negeri Sunan Kalijaga,Yogyakarta55281, Indonesia
Published: August 2021

This study aims to illustrate the effect of empathy on the role of the bystander towards bullying at school through moral disengagement as the mediator. Moral disengagement affects bystanders' role. In this case, an outsider or ignorant bystander indicates higher moral disengagement than a defender or defensive bystander. The subject were 245 high school students in the age of 15-17 years. The respondents acted as bystanders adapted from the Participant Role Questionnaire (PRQ) scale.  The researcher adopted the Basic Empathy Scale dan Moral Disengagement Scale as the measuring instrument. The data analysis employed a simple mediation analysis technique with bootstrapping method. The results indicated that first, there was a positive and significant effect of empathy on the role of defender bystander mediated by moral disengagement. Second, there was a negative and significant effect of empathy on reinforcer bystander's role towards bullying at schools as mediated by moral disengagement. Third, the study also indicated that there was no effect of empathy to the bystander's roles as an assistant, outsider, and aggressive defender through moral disengagement as a mediator. One of implications for future interventions in schools, for instance, bystander training emphasizing an effective way to act towards bullying at school.
Giving more enhances your happiness: Evidence from Indonesia
Authors:   The Australian National University, Canberra ACT 2600, Australia, Utama Radikal Yuda , Palani Herman ,   Center for Research in Islamic Economics and Business, Universitas Gadjah Mada,Yogyakarta55281, Indonesia, Rabbani Ahmad Zufar ,   Center for Research in Islamic Economics and Business, Universitas Gadjah Mada,Yogyakarta55281, Indonesia
Published: August 2021

Previous studies revealed that consuming activities and spending money to meet needs can improve individuals’ happiness. Our study showed that spending money, not for personal needs also has a big impact on individuals’ well-being. We used 26,464 observations of 4th  and 5th  waves of the Indonesian Family Life Survey (IFLS) to predict the expenditures for non-personal needs (known as prosocial expenditure) on one's subjective well-being. The estimation result of the probit model showed that pro-social expenditure had a positive correlation with subjective well-being. On average, those who spend more on charity are happier than people who spend less. We also found that prosocial expenditure among Muslim and non-Muslim observations had different effects on happiness and life satisfaction.
Perceptions and Attitudes Toward the Use of a Mobile Health App for Remote Monitoring of Gingivitis and Willingness to Pay for Mobile Health Apps (Part 3): Mixed Methods Study
Authors: Tobias Guy , Sgan-Cohen Harold , Spanier Assaf B , Mann Jonathan
Published: August 2021

Background

Gum infection, known as gingivitis, is a global issue. Gingivitis does not cause pain; however, if left untreated, it can worsen, leading to bad breath, bleeding gums, and even tooth loss, as the problem spreads to the underlying structures anchoring the teeth in the jaws. The asymptomatic nature of gingivitis leads people to postpone dental appointments until clinical signs are obvious or pain is evident. The COVID-19 pandemic has necessitated social distancing, which has caused many people to postpone dental visits and neglect gingival health. iGAM is a dental mobile health (mHealth) app that remotely monitors gum health, and an observational study demonstrated the ability of iGAM to reduce gingivitis. We found that a weekly dental selfie using the iGAM app reduced the signs of gingivitis and promoted oral health in a home-based setting.

Objective

The aim of this mixed methods study is to assess perceptions, attitudes, willingness to pay, and willingness to use an mHealth app.

Methods

The first qualitative phase of the study included eight semistructured interviews, and the second quantitative phase included data collected from responses to 121 questionnaires.

Results

There was a consensus among all interviewees that apps dealing with health-related issues (mHealth apps) can improve health. Three themes emerged from the interviews: the iGAM app is capable of improving health, the lack of use of medical apps, and a contradiction between the objective state of health and the self-definition of being healthy. Participants were grouped according to how they responded to the question about whether they believed that mHealth apps could improve their health. Participants who believed that mHealth apps can enhance health (mean 1.96, SD 1.01) had a higher willingness to pay for the service (depending on price) than those who did not believe in app efficacy (mean 1.31, SD 0.87; t119=−2417; P=.02). A significant positive correlation was found between the amount a participant was willing to pay and the benefits offered by the app (rs=0.185; P=.04).

Conclusions

Potential mHealth users will be willing to pay for app use depending on their perception of the app’s ability to help them personally, provided they define themselves as currently unhealthy.