bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 4 from The HSP90 Inhibitor Ganetespib Synergizes with the MET Kinase Inhibitor Crizotinib in both Crizotinib-Sensitive and -Resistant MET-Driven Tumor Models
Authors: Miyajima Naoto , Tsutsumi Shinji , Sourbier Carole , Beebe Kristin , Mollapour Mehdi , Rivas Candy , Yoshida Soichiro , Trepel Jane B. , Huang Ying , Tatokoro Manabu , Shinohara Nobuo , Nonomura Katsuya , Neckers Len
Published: April 2023

PDF file - 231K, Ganetespib inhibits MET activity and downstream signaling in cells expressing TKI-sensitive MET mutants.
Supplementary Figure 3 from LSECtin Expressed on Melanoma Cells Promotes Tumor Progression by Inhibiting Antitumor T-cell Responses
Authors: Xu Feng , Liu Jing , Liu Di , Liu Biao , Wang Min , Hu Zhiyuan , Du Xuemei , Tang Li , He Fuchu
Published: April 2023

PDF file - 90KB, Supplementary Figure 3 Confirmation of the surface expression of LSECtin on stable B16-mock and B16-LSECtin transfectants by flow cytometry.
Supplementary Figure 2 from LSECtin Expressed on Melanoma Cells Promotes Tumor Progression by Inhibiting Antitumor T-cell Responses
Authors: Xu Feng , Liu Jing , Liu Di , Liu Biao , Wang Min , Hu Zhiyuan , Du Xuemei , Tang Li , He Fuchu
Published: April 2023

PDF file - 31KB, Supplementary Figure 2 Determination of concentration of IL-6 and IL-10 within tumor.
Supplementary Figure 1 from Higher Frequencies of GARP+CTLA-4+Foxp3+ T Regulatory Cells and Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma Patients Are Associated with Impaired T-Cell Functionality
Authors: Kalathil Suresh , Lugade Amit A. , Miller Austin , Iyer Renuka , Thanavala Yasmin
Published: April 2023

PDF file - 81K, Supplementary Figure 1. (A) q-PCR analysis of Foxp3 gene expression from PBMCs of HCC patients (n=10) and healthy donors (n=10). Lines represent mean values of Foxp3 mRNA copies normalized to GAPDH control (**P = 0.005). (B) Correlation between Foxp3 mRNA copies and CD4+FoxP3+ Treg frequency (Spearman correlation = 0.49; P = 0.005).
Supplementary Methods, Figures Legends 1-10 from Histone Deacetylase Inhibitor AR-42 Differentially Affects Cell-cycle Transit in Meningeal and Meningioma Cells, Potently Inhibiting NF2-Deficient Meningioma Growth
Authors: Burns Sarah S. , Akhmametyeva Elena M. , Oblinger Janet L. , Bush Matthew L. , Huang Jie , Senner Volker , Chen Ching-Shih , Jacob Abraham , Welling D. Bradley , Chang Long-Sheng
Published: April 2023

PDF file - 102K
Supplementary Table 1-3 from MicroRNA-Related Genetic Variants Associated with Clinical Outcomes in Early-Stage Non–Small Cell Lung Cancer Patients
Authors: Pu Xia , Roth Jack A. , Hildebrandt Michelle A.T. , Ye Yuanqing , Wei Hua , Minna John D. , Lippman Scott M. , Wu Xifeng
Published: April 2023

Supplementary Table 1-3 PDF file - 162K, Supplementary tables 1 and 2 include effect of selected SNPs on overall survival or recurrence in early stage NSCLC patients; Supplementary table 3 includes all the SNPs selected in the analysis
Supplementary Figure 7 from Cell Surface Receptor FPR2 Promotes Antitumor Host Defense by Limiting M2 Polarization of Macrophages
Authors: Liu Ying , Chen Keqiang , Wang Chunyan , Gong Wanghua , Yoshimura Teizo , Liu Mingyong , Wang Ji Ming
Published: April 2023

PDF file - 113K, The expression of chemokine receptors by tumor-associated macrophages (TAMs)
Supplementary Figure Legends from Predictive Performance of Microarray Gene Signatures: Impact of Tumor Heterogeneity and Multiple Mechanisms of Drug Resistance
Authors: Ng Charlotte K.Y. , Weigelt Britta , A'Hern Roger , Bidard Francois-Clement , Lemetre Christophe , Swanton Charles , Shen Ronglai , Reis-Filho Jorge S.
Published: April 2023

PDF file - 60K
Supplementary Figure S3 from LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis
Authors: Cox Thomas R. , Bird Demelza , Baker Ann-Marie , Barker Holly E. , Ho Melisa W-Y. , Lang Georgina , Erler Janine T.
Published: April 2023

Supplementary Figure S3 PDF file - 559K, Fibroblast activation and matrix remodelling leads to increased proliferation and colonisation by tumour cells
Supplementary Figures 1 - 5, Table 1 from EGFR-TKI Resistance Due to BIM Polymorphism Can Be Circumvented in Combination with HDAC Inhibition
Authors: Nakagawa Takayuki , Takeuchi Shinji , Yamada Tadaaki , Ebi Hiromichi , Sano Takako , Nanjo Shigeki , Ishikawa Daisuke , Sato Mitsuo , Hasegawa Yoshinori , Sekido Yoshitaka , Yano Seiji
Published: April 2023

PDF file - 785K, Supplementary Figure 1. Expression of total BIM and ratio of BIM isoforms in NSCLC cell lines. Supplementary Figure 2. Flow cytometric analysis showing that EGFR mutated cell lines carrying the BIM polymorphism have low susceptibility to gefitinib-induced apoptosis. Supplementary Figure 3. Vorinostat-induced up-regulation of BIM enhances apoptosis in the HCC2279 cell line with the BIM polymorphism.Supplementary Figure 4. Knockdown or overexpression of BIM affects activation of caspase-3/7 induced by gefitinib and vorinostat in EGFR mutant cells with BIM polymorphism. Supplementary Figure 5. Detection of BIM polymorphism in human peripheral blood mononuclear cells (PBMC) and serum. Supplementary Table 1. Status of EGFR mutation and BIM polymorphism in NSCLC cell lines.
Supplementary Methods, Figures 1-3 from Impact of Tumor Progression on Cancer Incidence Curves
Authors: Luebeck E. Georg , Curtius Kit , Jeon Jihyoun , Hazelton William D.
Published: April 2023

PDF file - 8.8MB
Supplementary Table 4 from Elimination of IL-10–Inducing T-Helper Epitopes from an IGFBP-2 Vaccine Ensures Potent Antitumor Activity
Authors: Cecil Denise L. , Holt Gregory E. , Park Kyong Hwa , Gad Ekram , Rastetter Lauren , Childs Jennifer , Higgins Doreen , Disis Mary L.
Published: April 2023

PDF file - 51KB, Human protein sequence homologies for IGFBP-2 C-terminus.
Supplementary Figure 1 from CUL3 and NRF2 Mutations Confer an NRF2 Activation Phenotype in a Sporadic Form of Papillary Renal Cell Carcinoma
Authors: Ooi Aikseng , Dykema Karl , Ansari Asif , Petillo David , Snider John , Kahnoski Richard , Anema John , Craig David , Carpten John , Teh Bin-Tean , Furge Kyle A.
Published: April 2023

PDF file - 772K, Knowledge-guided strategy of driver mutation discovery for NRF2 activation in sporadic PRCC2
Supplementary Figure 1 from Nitroreductase, a Near-Infrared Reporter Platform for In Vivo Time-Domain Optical Imaging of Metastatic Cancer
Authors: McCormack Emmet , Silden Elisabeth , West Richard M. , Pavlin Tina , Micklem David R. , Lorens James B. , Haug Bengt Erik , Cooper Michael E. , Gjertsen Bjørn Tore
Published: April 2023

PDF file - 402K, Synthesis, mechanism and spectral characteristics of CytoCy5S.
Supplementary Figure 1 from Trask Loss Enhances Tumorigenic Growth by Liberating Integrin Signaling and Growth Factor Receptor Cross-Talk in Unanchored Cells
Authors: Spassov Danislav S. , Wong Ching Hang , Wong Sunny Y. , Reiter Jeremy F. , Moasser Mark M.
Published: April 2023

PDF file - 127K, Lung metastases in PyMT mice
Supplementary Movie 1 from A Chimeric Receptor with NKG2D Specificity Enhances Natural Killer Cell Activation and Killing of Tumor Cells
Authors: Chang Yu-Hsiang , Connolly John , Shimasaki Noriko , Mimura Kousaku , Kono Koji , Campana Dario
Published: April 2023

WMV file - 3260K, Live cell confocal photography of mock- (left panel) and NKG2D-DAP10-CD3ξ-transduced NK cells (right panel) co-cultured U2 OS osteosarcoma cells. NK cells were labeled with PKH26 (Sigma) before culture and appear red. Microscopy was performed with a Nikon TE2000E2 microscope equipped with a Nikon C1Si confocal using 488nm and 561nm DPSS lasers for excitation. Temperature was maintained at 37oC and CO2 at 5% using an environmental control chamber. Images were acquired with a Nikon 40x 1.3 NA DIC objective every 30s for 2hr using Nikon EZC1 software. Imaris (Bitplane Scientific Software) was used to analyze speed and displacement of NK cells.
Supplementary Figures 1 - 6 from A Meta-analysis of Lung Cancer Gene Expression Identifies PTK7 as a Survival Gene in Lung Adenocarcinoma
Authors: Chen Ron , Khatri Purvesh , Mazur Pawel K. , Polin Melanie , Zheng Yanyan , Vaka Dedeepya , Hoang Chuong D. , Shrager Joseph , Xu Yue , Vicent Silvestre , Butte Atul J. , Sweet-Cordero E. Alejandro
Published: April 2023

PDF file - 462KB, Forest plots summarizing the overexpression of the 11 genes from discovery meta-analysis (S1). Forest plots summarizing the overexpression of the 11 genes from validation meta-analysis (S2). Six genes of the original 11 gene ADC signature are also overexpressed in ADC relative to other NSCLC histological subtypes (S3). Expression of PTK7 in an ADC tissue microarray and in a mouse model of lung adenocarcinoma (S4). Correlation of sensitivity to PTK7 knock-down with mutations and expression (S5). MKK7-JNK pathway dysregulation upon PTK7 knock-down (S6).
Supplementary Table 5 from Attenuation of microRNA-126 Expression That Drives CD34+38− Stem/Progenitor Cells in Acute Myeloid Leukemia Leads to Tumor Eradication
Authors: de Leeuw David C. , Denkers Fedor , Olthof Marjolein C. , Rutten Arjo P. , Pouwels Walter , Jan Schuurhuis Gerrit , Ossenkoppele Gert J. , Smit Linda
Published: April 2023

XLSX file - 54KB, Genes correlated with microRNA-126 expression in 163 AML patients show overlap with stem cell genes: Genes positively and negatively associated with miR-126 expression in 163 AML patients as published by (34). 854 genes were significantly correlated in a Spearman's rank correlation analysis with a significance threshold of univariate tests <0.001. Correlation coefficient, Parametric p-value and FDR are shown. Correlated genes were compared with the previously published HSC and LSC gene signatures of Eppert et al. (7). Genes that are associated with miR-126 and are also found in the LSC signature are shown in columns LSC-R FDR <0.05 and FDR <.0.01. Correlated genes that overlap with HSC signatures are shown under HSC-R <0.05. N/A, no overlap.
Supplementary Figures from Genome-wide Profiling of Genetic Synthetic Lethality Identifies CDK12 as a Novel Determinant of PARP1/2 Inhibitor Sensitivity
Authors: Bajrami Ilirjana , Frankum Jessica R. , Konde Asha , Miller Rowan E. , Rehman Farah L. , Brough Rachel , Campbell James , Sims David , Rafiq Rumana , Hooper Sean , Chen Lina , Kozarewa Iwanka , Assiotis Ioannis , Fenwick Kerry , Natrajan Rachael , Lord Christopher J. , Ashworth Alan
Published: April 2023

PDF file 3292K, Supplementary Figure S1. Genome wide shRNA screen information. Supplementary Figure S2. Validation of ATAD5 as a genetic determinant of olaparib response. Supplementary Figure S3. A working model of PARP1/2 inhibitor-induced DNA repair. Supplementary Figure S4. Inhibition of CDK12 sensitises serous ovarian cancer cells to olaparib and cisplatin. Supplementary Figure S5. CDK12 silencing and the impact on expression of DNA repair proteins. Supplementary Figure S6. Targeting of CCNK sensitises serous ovarian cancer cells to olaparib and cisplatin. Supplementary Figure S7. Animal body weights from in vivo study
Supplementary Figure Legend from Inhibitor-Sensitive FGFR2 and FGFR3 Mutations in Lung Squamous Cell Carcinoma
Authors: Liao Rachel G. , Jung Joonil , Tchaicha Jeremy , Wilkerson Matthew D. , Sivachenko Andrey , Beauchamp Ellen M. , Liu Qingsong , Pugh Trevor J. , Pedamallu Chandra Sekhar , Hayes D. Neil , Gray Nathanael S. , Getz Gad , Wong Kwok-Kin , Haddad Robert I. , Meyerson Matthew , Hammerman Peter S.
Published: April 2023

PDF file - 46K
Supplementary Figure 4 from Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis
Authors: Doherty Joanne R. , Yang Chunying , Scott Kristen E.N. , Cameron Michael D. , Fallahi Mohammad , Li Weimin , Hall Mark A. , Amelio Antonio L. , Mishra Jitendra K. , Li Fangzheng , Tortosa Mariola , Genau Heide Marika , Rounbehler Robert J. , Lu Yunqi , Dang Chi V. , Kumar K. Ganesh , Butler Andrew A. , Bannister Thomas D. , Hooper Andrea T. , Unsal-Kacmaz Keziban , Roush William R. , Cleveland John L.
Published: April 2023

PDF file - 116K, Structure of the MCT1 inhibitors AR-C122982 (SR13800) and AR-C155858 (SR13801). Cell cycle analysis, viability, clonogenecity and lactate transport in the indicated cells treated with SR13800. Proliferation of MCF7 cells overexpressing MCT1 or MCT4.
Supplementary Table 4 from Dendritic Cells in Tumor-Associated Tertiary Lymphoid Structures Signal a Th1 Cytotoxic Immune Contexture and License the Positive Prognostic Value of Infiltrating CD8+ T Cells
Authors: Goc Jérémy , Germain Claire , Vo-Bourgais Thi Kim Duy , Lupo Audrey , Klein Christophe , Knockaert Samantha , de Chaisemartin Luc , Ouakrim Hanane , Becht Etienne , Alifano Marco , Validire Pierre , Remark Romain , Hammond Scott A. , Cremer Isabelle , Damotte Diane , Fridman Wolf-Herman , Sautès-Fridman Catherine , Dieu-Nosjean Marie-Caroline
Published: April 2023

PDF file - 95K, Comparison of different methods used for the stratification of patients according to the density of mature DC, stromal CD8+ T cells or tumor nest CD8+ T cells.
Supplementary Figure S4 from Adiponectin Receptor Signaling on Dendritic Cells Blunts Antitumor Immunity
Authors: Tan Peng H. , Tyrrell Helen E.J. , Gao Liquan , Xu Danmei , Quan Jianchao , Gill Dipender , Rai Lena , Ding Yunchuan , Plant Gareth , Chen Yuan , Xue John Z. , Handa Ashok I. , Greenall Michael J. , Walsh Kenneth , Xue Shao-An
Published: April 2023

APN signals through AdipoR1 to induce IL-10 production via activation of AMPK and MAPKp38.
Supplementary Figure 1 from Dendritic Cells in Tumor-Associated Tertiary Lymphoid Structures Signal a Th1 Cytotoxic Immune Contexture and License the Positive Prognostic Value of Infiltrating CD8+ T Cells
Authors: Goc Jérémy , Germain Claire , Vo-Bourgais Thi Kim Duy , Lupo Audrey , Klein Christophe , Knockaert Samantha , de Chaisemartin Luc , Ouakrim Hanane , Becht Etienne , Alifano Marco , Validire Pierre , Remark Romain , Hammond Scott A. , Cremer Isabelle , Damotte Diane , Fridman Wolf-Herman , Sautès-Fridman Catherine , Dieu-Nosjean Marie-Caroline
Published: April 2023

PDF file - 200K, Twelve-color analysis of the immune cell populations in freshly resected tumors.
Supplementary Methods from ALCAM/CD166 Is a TGF-β–Responsive Marker and Functional Regulator of Prostate Cancer Metastasis to Bone
Authors: Hansen Amanda G. , Arnold Shanna A. , Jiang Ming , Palmer Trenis D. , Ketova Tatiana , Merkel Alyssa , Pickup Michael , Samaras Susan , Shyr Yu , Moses Harold L. , Hayward Simon W. , Sterling Julie A. , Zijlstra Andries
Published: April 2023

PDF - 82K, Description of additional methods and procedures used in the study.
Supplementary Figure 5 from microRNA-148a Is a Prognostic oncomiR That Targets MIG6 and BIM to Regulate EGFR and Apoptosis in Glioblastoma
Authors: Kim Jungeun , Zhang Ying , Skalski Michael , Hayes Josie , Kefas Benjamin , Schiff David , Purow Benjamin , Parsons Sarah , Lawler Sean , Abounader Roger
Published: April 2023

PDF file - 25K, MIG6 mediates the effects of miR-148a on cell proliferation.
Supplementary Figure 5 from EGF Receptor Activates MET through MAPK to Enhance Non–Small Cell Lung Carcinoma Invasion and Brain Metastasis
Authors: Breindel Jerrica L. , Haskins Jonathan W. , Cowell Elizabeth P. , Zhao Minghui , Nguyen Don X. , Stern David F.
Published: April 2023

PDF file - 886K, MET promotes EGF-induced migration and invasion of NSCLC cell lines.
Supplementary Figure 1 from Comparative Functional Analysis of DPYD Variants of Potential Clinical Relevance to Dihydropyrimidine Dehydrogenase Activity
Authors: Offer Steven M. , Fossum Croix C. , Wegner Natalie J. , Stuflesser Alexander J. , Butterfield Gabriel L. , Diasio Robert B.
Published: April 2023

PDF file - 93KB, DPD enzyme kinetics.
Supplementary Figure 2 from HuR Posttranscriptionally Regulates WEE1: Implications for the DNA Damage Response in Pancreatic Cancer Cells
Authors: Lal Shruti , Burkhart Richard A. , Beeharry Neil , Bhattacharjee Vikram , Londin Eric R. , Cozzitorto Joseph A. , Romeo Carmella , Jimbo Masaya , Norris Zoë A. , Yeo Charles J. , Sawicki Janet A. , Winter Jordan M. , Rigoutsos Isidore , Yen Timothy J. , Brody Jonathan R.
Published: April 2023

PDF file - 658KB, HuR manipulation sensitizes PDA cells to chemotherapeutics agents.
Supplemental Table S2 from ATR Inhibitors VE-821 and VX-970 Sensitize Cancer Cells to Topoisomerase I Inhibitors by Disabling DNA Replication Initiation and Fork Elongation Responses
Authors: Jossé Rozenn , Martin Scott E. , Guha Rajarshi , Ormanoglu Pinar , Pfister Thomas D. , Reaper Philip M. , Barnes Christopher S. , Jones Julie , Charlton Peter , Pollard John R. , Morris Joel , Doroshow James H. , Pommier Yves
Published: April 2023

Supplemental Table S2. Top Ingenuity canonical pathways enriched by genes among the top RSA candidates (42 genes, RSA p{less than or equal to} 0.001). A Benjamini-Hochberg multiple testing correction p-value < 0.05 was used as a cutoff.
Supplementary Figure 6 from Increased Dietary Vitamin D Suppresses MAPK Signaling, Colitis, and Colon Cancer
Authors: Meeker Stacey , Seamons Audrey , Paik Jisun , Treuting Piper M. , Brabb Thea , Grady William M. , Maggio-Price Lillian
Published: April 2023

PDF file - 60K, Helicobacter colonization is not altered by increased dietary vitamin D.
Supplementary Figure 1 from Identification of a Cyclin D1 Network in Prostate Cancer That Antagonizes Epithelial–Mesenchymal Restraint
Authors: Ju Xiaoming , Casimiro Mathew C. , Gormley Michael , Meng Hui , Jiao Xuanmao , Katiyar Sanjay , Crosariol Marco , Chen Ke , Wang Min , Quong Andrew A. , Lisanti Michael P. , Ertel Adam , Pestell Richard G.
Published: April 2023

PDF file - 83K, Cyclin D1 is required for prostate development in vivo.
Supplementary Figure 6 from Germline Mutations in BAP1 Impair Its Function in DNA Double-Strand Break Repair
Authors: Ismail Ismail Hassan , Davidson Riley , Gagné Jean-Philippe , Xu Zhi Zhong , Poirier Guy G. , Hendzel Michael J.
Published: April 2023

PDF file - 47KB, Figure S6. BRCA1 siRNA efficiently knocked down BRCA1 in cells. (A) U2OS cells were transfected with control (Ctr) siRNA or BRCA1 siRNA for 48 hr. Nuclear extracts were prepared from these cells, and BRCA1 expression was determined by immunoblotting using BRCA1 specific antibody. As a loading control, membranes were probed for actin. (B) The specificity of the BRCA1 antibody used in this study. Immunostaining of U2OS cells transfected with control (Ctr) or BRCA1 specific siRNA (BRCA1 siRNA). Cells were transfected with the indicated siRNA for 48 hr. Cells were then irradiated with 2 Gy, allowed to recover for 1 hr and immunostained with BRCA1 antibody and counterstained with DAPI to reveal DNA. (C) Immunostaining of BMI1 and 53BP1 in response to DNA damage. U2OS were transfected with control (Ctr shRNA) or BAP1 specific shRNA (BAP1 shRNA) for 48 hr. Cell were then irradiated with 2 Gy of IR and left to recover for 30 min. Cells were immunostained with BMI1 and 53BP1 antibodies and counterstained with DAPI to reveal DNA. Bars, 5 microm.
Supplementary Figures 1-5 from DDB2: A Novel Regulator of NF-κB and Breast Tumor Invasion
Authors: Ennen Marie , Klotz Rémi , Touche Nadège , Pinel Sophie , Barbieux Claire , Besancenot Vanessa , Brunner Emilie , Thiebaut Denise , Jung Alain C. , Ledrappier Sonia , Domenjoud Lionel , Abecassis Joseph , Plénat François , Grandemange Stéphanie , Becuwe Philippe
Published: April 2023

PDF - 636K, Supplementary Figure 1: DDB2 reduces migration abilities of the aggressive breast tumor MDA-MB231 cell line in wound healing-induced migration assay. Supplementary Figure 2: Knockdown of DDB2 expression induces migratory and invasive abilities in vitro of nonaggressive breast tumor T47D cell line. Supplementary Figure 3: DDB2 expression is inversely correlated with the histological SBR grade tumors. Supplementary Figure 4: DDB2 is involved in upregulation of IkBa gene in MCF-7 cells through a binding site localized in the IkBa proximal promoter. Supplementary Figure 5: NF-kB is involved in the migration and invasion abilities of MDA-MB231 and SKBR3 Neo control cells.
Supplementary Figure 2 from WEE1 Inhibition Alleviates Resistance to Immune Attack of Tumor Cells Undergoing Epithelial–Mesenchymal Transition
Authors: Hamilton Duane H. , Huang Bruce , Fernando Romaine I. , Tsang Kwong-Yok , Palena Claudia
Published: April 2023

PDF file - 122KB, Figure S2. Mechanism of resistance to immune-mediated cytotoxic lysis.
Supplementary Figures 1 - 8 from Identification of Alternative Splicing Events Regulated by the Oncogenic Factor SRSF1 in Lung Cancer
Authors: de Miguel Fernando J. , Sharma Ravi D. , Pajares María J. , Montuenga Luis M. , Rubio Angel , Pio Ruben
Published: April 2023

PDF file - 1020K, Supplementary Figure S1. A cassette event in MAPT gene. Supplementary Figure S2. Validation of the cell model of SRSF1 down-regulation. Supplementary Figure S3. Validation of differential alternative splicing events from the top 20 genes selected by the ExonPointer algorithm using microarray data from the Oryzon platform. Supplementary Figure S4. Validation of differential alternative splicing events in a set of genes selected by the ExonPointer algorithm using microarray data from the GeneSplice platform. Supplementary Figure S5. Ingenuity pathway network related to "Cell Morphology, Developmental Disorder and Hereditary Disorder" and derived from the analysis of differential alternative splicing events after SRSF1 down-regulation. Supplementary Figure S6 Ingenuity pathway network with annotations: "Cell Cycle, Cellular Assembly and Organization and Cellular Movement" and derived from the analysis of differential alternative splicing events after SRSF1 down-regulation. Supplementary Figure S7. Ingenuity pathway network with annotations: "Organismal Development, Cancer, Cell Death and Survival" and derived from the analysis of differential alternative splicing events after SRSF1 down-regulation. Supplementary Figure S8. Growth effect of PRRC2C splice variants in HCC827, H2087 and HCC95 cell growth.
Supplementary Figure 8 from Accumulation of Cytosolic Calcium Induces Necroptotic Cell Death in Human Neuroblastoma
Authors: Nomura Motonari , Ueno Ayumi , Saga Kotaro , Fukuzawa Masahiro , Kaneda Yasufumi
Published: April 2023

PDF - 57K, The expression of CaMK IIα is necessary for the HVJ-E-induced cell death in SK-N-SH cells.
Supplementary Figure 3 from Accumulation of Cytosolic Calcium Induces Necroptotic Cell Death in Human Neuroblastoma
Authors: Nomura Motonari , Ueno Ayumi , Saga Kotaro , Fukuzawa Masahiro , Kaneda Yasufumi
Published: April 2023

PDF - 61K, Downstream pathway of necroptosis is associated with HVJ-E-induced cell death in SK-N-SH cells.
Supplementary Figure 2 from Accumulation of Cytosolic Calcium Induces Necroptotic Cell Death in Human Neuroblastoma
Authors: Nomura Motonari , Ueno Ayumi , Saga Kotaro , Fukuzawa Masahiro , Kaneda Yasufumi
Published: April 2023

PDF - 94K, The expression level of caspase-8 regulates the HVJ-E-induced cell death in SK-N-SH cells.
Supplementary Figure 6 from Mechanistic Elucidation of the Antitumor Properties of Withaferin A in Breast Cancer
Authors: Nagalingam Arumugam , Kuppusamy Panjamurthy , Singh Shivendra V. , Sharma Dipali , Saxena Neeraj K.
Published: April 2023

PDF file - 141KB, Supplemental Figure 6 ERK and RSK activation is important for WFA-mediated inhibition of clonogenicity of breast cancer cells.
Supplementary Figure 1 from Expression of Variant Isoforms of the Tyrosine Kinase SYK Determines the Prognosis of Hepatocellular Carcinoma
Authors: Hong Jian , Yuan Yunfei , Wang Jianping , Liao Yadi , Zou Ruhai , Zhu Chuanlong , Li Binkui , Liang Yi , Huang Pinzhu , Wang Zongwei , Lin Wenyu , Zeng Yixin , Le Dai Jia , Chung Raymond T.
Published: April 2023

PDF file - 122KB, Supplementary Figure 1. (A) Domain structure of SYK(L) and SYK(S). Sequence and cross-species homology of 23 amino acid residues deleted in SYK(S) are shown. (B) Relative position of PCR primers unique for SYK(L) or SYK(S).
Table S1. Genes with Altered Expression in OV3/H1.3(H) Cells. from Histone H1.3 Suppresses H19 Noncoding RNA Expression and Cell Growth of Ovarian Cancer Cells
Authors: Medrzycki Magdalena , Zhang Yunzhe , Zhang Weijia , Cao Kaixiang , Pan Chenyi , Lailler Nathalie , McDonald John F. , Bouhassira Eric E. , Fan Yuhong
Published: April 2023

Table S1. Genes with Altered Expression in OV3/H1.3(H) Cells. Genes upregulated or downregulated ({greater than or equal to}2-fold) are shown.
Data Supplement from Crosstalk between Glioma-Initiating Cells and Endothelial Cells Drives Tumor Progression
Authors: Jeon Hye-Min , Kim Sung-Hak , Jin Xun , Park Jong Bae , Kim Se Hoon , Joshi Kaushal , Nakano Ichiro , Kim Hyunggee
Published: April 2023

Supplementary Figure S4. PDGF-NOS-ID4-miR-129 signaling activates Jagged1-Notch signaling in endothelial cells.
Supplementary Figure S3 from Distinct Functions of Epidermal and Myeloid-Derived VEGF-A in Skin Tumorigenesis Mediated by HPV8
Authors: Ding Xiaolei , Lucas Tina , Marcuzzi Gian P. , Pfister Herbert , Eming Sabine A.
Published: April 2023

Supplementary Figure S3. FACS sorted keratinocytes.
Supplementary Figure S2 from Distinct Functions of Epidermal and Myeloid-Derived VEGF-A in Skin Tumorigenesis Mediated by HPV8
Authors: Ding Xiaolei , Lucas Tina , Marcuzzi Gian P. , Pfister Herbert , Eming Sabine A.
Published: April 2023

Supplementary Figure S2. Blocking VEGFR2 shows no impact on epidermal keratinocyte proliferation and apoptosis.
Data Supplement from Heparanase Cooperates with Ras to Drive Breast and Skin Tumorigenesis
Authors: Boyango Ilanit , Barash Uri , Naroditsky Inna , Li Jin-Ping , Hammond Edward , Ilan Neta , Vlodavsky Israel
Published: April 2023

Supplementary Figure Legends
Supplementary Figure S1 from Distinct Functions of Epidermal and Myeloid-Derived VEGF-A in Skin Tumorigenesis Mediated by HPV8
Authors: Ding Xiaolei , Lucas Tina , Marcuzzi Gian P. , Pfister Herbert , Eming Sabine A.
Published: April 2023

Supplementary Figure S1. Myeloid cell-restricted VEGF shows no impact on immune cell recruitment during early stage wound-induced papilloma formation in HPV8 mice.
Supplementary Table S1 from Complex Formation and Function of Estrogen Receptor α in Transcription Requires RIP140
Authors: Rosell Meritxell , Nevedomskaya Ekaterina , Stelloo Suzan , Nautiyal Jaya , Poliandri Ariel , Steel Jennifer H. , Wessels Lodewyk F.A. , Carroll Jason S. , Parker Malcolm G. , Zwart Wilbert
Published: April 2023

Supplementary Table S1. Primer sequences with ChIP-PCR and qRT-PCR analyses.
Supplementary Table 1 from ABCB5 Maintains Melanoma-Initiating Cells through a Proinflammatory Cytokine Signaling Circuit
Authors: Wilson Brian J. , Saab Karim R. , Ma Jie , Schatton Tobias , Pütz Pablo , Zhan Qian , Murphy George F. , Gasser Martin , Waaga-Gasser Ana Maria , Frank Natasha Y. , Frank Markus H.
Published: April 2023

PDF file - 52K, Differentially expressed genes in ABCB5-KD melanoma cells versus controls.
Supplementary Data from Genetic Evidence of a Precisely Tuned Dysregulation in the Hypoxia Signaling Pathway during Oncogenesis
Authors: Couvé Sophie , Ladroue Charline , Laine Elodie , Mahtouk Karène , Guégan Justine , Gad Sophie , Le Jeune Hélène , Le Gentil Marion , Nuel Gregory , Kim William Y. , Lecomte Bernard , Pagès Jean-Christophe , Collin Christine , Lasne Françoise , Benusiglio Patrick R. , Bressac-de Paillerets Brigitte , Feunteun Jean , Lazar Vladimir , Gimenez-Roqueplo Anne-Paule , Mazure Nathalie M. , Dessen Philippe , Tchertanov Luba , Mole David R. , Kaelin William , Ratcliffe Peter , Richard Stéphane , Gardie Betty
Published: April 2023

Supplementary Material and Methods and Legend of Supplementary Tables and Figures
Supplementary Figure Legends, Tables 1 - 2 from CtBP2 Modulates the Androgen Receptor to Promote Prostate Cancer Progression
Authors: Takayama Ken-ichi , Suzuki Takashi , Fujimura Tetsuya , Urano Tomohiko , Takahashi Satoru , Homma Yukio , Inoue Satoshi
Published: April 2023

Supplementary Table S1. Primer sequences. Supplementary Table S2. Association between CtBP2 immunohistochemical status and clinicopathological parameters in 105 human prostate carcinomas.
Supplementary Figure 7. Effects of progestin, MPA, and Dex on E2-stimulated growth in MCF-7:WS8 cells. from Molecular Modulation of Estrogen-Induced Apoptosis by Synthetic Progestins in Hormone Replacement Therapy: An Insight into the Women's Health Initiative Study
Authors: Sweeney Elizabeth E. , Fan Ping , Jordan V. Craig
Published: April 2023

Supplementary Figure 6. MCF-8:WS8 cells were transferred to estrogen-free medium for 3 days. The, cells were loaded in 24-well plates. A. MCF-7:WS8 cells were treated with vehicle, 0.01µM R5020, 1nM E2, and 0.01µM R5020+1nM E2. Cells were harvested after 7 days treatment and DNA was quantified. P<0.05, * compared with control. P<0.001, ** compared with control. B. MCF-7:WS8 cells were treated with vehicle, different concentrations of MPA as indicated, 1nM E2, and different concentrations of MPA+1nM E2. Cells were harvested after 7 days treatment and DNA was quantified. P<0.05, * compared with E2-treated group. P<0.001, ** compared with control. C. MCF-7:WS8 cells were treated with vehicle, different concentrations of Dex as indicated, 1nM E2, and different concentrations of Dex+1nM E2. Cells were harvested after 7 days treatment and DNA was quantified. P<0.05, * compared with E2-treated group. P<0.001, ** compared with control.
Supplementary Video 4 from Deubiquitination of γ-Tubulin by BAP1 Prevents Chromosome Instability in Breast Cancer Cells
Authors: Zarrizi Reihaneh , Menard Julien Albert , Belting Mattias , Massoumi Ramin
Published: April 2023

Live cell microscopy of MDA-MB-468 inducibly expressing empty expression plasmid and transiently transfected with H2B-GFP. The movie shows aberrant anaphase.
Table S1 from Oncogenic KRAS Confers Chemoresistance by Upregulating NRF2
Authors: Tao Shasha , Wang Shue , Moghaddam Seyed Javad , Ooi Aikseng , Chapman Eli , Wong Pak K. , Zhang Donna D.
Published: April 2023

Table S1. Cisplatin toxicity as a function of KRAS, NRF2, KEAP1, and P53. The response to cisplatin-mediated toxicity of the listed NSCLC was measured by functional impairment of mitochondria using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method. LD50s are listed. The coding regions of NRF2 and KRAS were sequenced and the status of each gene is listed. The mutation information for KEAP1 and TP53 was obtained from the literature. The references can be found in the supporting references according to the numbers in the table.
Supplementary Figure 2 from The TGFβ–miR200–MIG6 Pathway Orchestrates the EMT-Associated Kinase Switch That Induces Resistance to EGFR Inhibitors
Authors: Izumchenko Evgeny , Chang Xiaofei , Michailidi Christina , Kagohara Luciane , Ravi Rajani , Paz Keren , Brait Mariana , Hoque Mohammad O. , Ling Shizhang , Bedi Atul , Sidransky David
Published: April 2023

PDF file - 108KB, TGFbeta induces EMT-associated kinase switch promotes erlotinib-resistance of tumor cells. A. Erlotinib sensitive cell lines H292 and SCC-S were treated with TGFβ1 (4 ng/ml) for 21 days and immunoblot analysis was performed with indicated antibodies. B. Parental and TGFbeta-induced H358 and SCC-S cells were treated with erlotinib for 72 hours and cell viability was assayed. Values were set at 100% for untreated controls. C. Protein lysates were extracted from H358 and SCC-S cells treated or untreated with TGFbeta for 21 days and immunoblot analysis was performed with antibodies against indicated phospho RTKs. Beta-actin was used as a loading control.
Supplemental Figure S3 from H3K9 Histone Methyltransferase, KMT1E/SETDB1, Cooperates with the SMAD2/3 Pathway to Suppress Lung Cancer Metastasis
Authors: Wu Pei-Chun , Lu Jeng-Wei , Yang Jer-Yen , Lin I-Hsuan , Ou Da-Liang , Lin Yu-Hsiang , Chou Kuan-Hsien , Huang Wen-Feng , Wang Wan-Ping , Huang Yih-Leh , Hsu Chiun , Lin Liang-In , Lin Yueh-Min , Shen C.-K. James , Tzeng Tsai-Yu
Published: April 2023

KMT1E inhibits filopodia formation in sublines cells.
Supplemental Figure Legends from H3K9 Histone Methyltransferase, KMT1E/SETDB1, Cooperates with the SMAD2/3 Pathway to Suppress Lung Cancer Metastasis
Authors: Wu Pei-Chun , Lu Jeng-Wei , Yang Jer-Yen , Lin I-Hsuan , Ou Da-Liang , Lin Yu-Hsiang , Chou Kuan-Hsien , Huang Wen-Feng , Wang Wan-Ping , Huang Yih-Leh , Hsu Chiun , Lin Liang-In , Lin Yueh-Min , Shen C.-K. James , Tzeng Tsai-Yu
Published: April 2023

Supplemental Figure Legends
Data Supplement from The RAC1 P29S Hotspot Mutation in Melanoma Confers Resistance to Pharmacological Inhibition of RAF
Authors: Watson Ian R. , Li Liren , Cabeceiras Peter K. , Mahdavi Mozhdeh , Gutschner Tony , Genovese Giannicola , Wang Guocan , Fang Zhuangna , Tepper James M. , Stemke-Hale Katherine , Tsai Kenneth Y. , Davies Michael A. , Mills Gordon B. , Chin Lynda
Published: April 2023

Supplementary Table 2. % viability at 1uM drug treatment compared to DMSO control for the NRAS Q61K mutant cell lines, CP66, HMVII, and WM3060 (expresses RAC1 P29S) are shown.
Supplementary Figure 1 from CD66+ Cells in Cervical Precancers Are Partially Differentiated Progenitors with Neoplastic Traits
Authors: Pattabiraman Chitra , Hong Shiyuan , Gunasekharan Vignesh K. , Pranatharthi Annapurna , Bajaj Jeevisha , Srivastava Sweta , Krishnamurthy H. , Ammothumkandy Aswathy , Giri Venkat G. , Laimins Laimonis A. , Krishna Sudhir
Published: April 2023

Supplementary Figure 1. CD66High cells have high DNMT1, Notch1 and comparable levels of KRT14 to CD66Low cells
Supplementary Figures 1 - 5 from Oxidative Stress Activates SIRT2 to Deacetylate and Stimulate Phosphoglycerate Mutase
Authors: Xu Yanping , Li Fulong , Lv Lei , Li Tingting , Zhou Xin , Deng Chu-Xia , Guan Kun-Liang , Lei Qun-Ying , Xiong Yue
Published: April 2023

PDF file - 104KB, Characterization of anti-acetyl-PGAM2(K100) antibody (S1). The endogenous activity of PGAM correlates with K100 acetylation level in different tissues (S2). Acetylation of K100 doesn't affect PGAM dimerization (S3). SIRT2 deacetylates PGAM2 (S4). NAM, but not TSA, decreases PGAM2 enzyme activity (S5).
Supplemental Figure 5 from HTLV-1 bZIP Factor HBZ Promotes Cell Proliferation and Genetic Instability by Activating OncomiRs
Authors: Vernin Céline , Thenoz Morgan , Pinatel Christiane , Gessain Antoine , Gout Olivier , Delfau-Larue Marie-Hélène , Nazaret Nicolas , Legras-Lachuer Catherine , Wattel Eric , Mortreux Franck
Published: April 2023

Supplemental Figure 5. Cell death evaluation
Supplemental Figure 3 from HTLV-1 bZIP Factor HBZ Promotes Cell Proliferation and Genetic Instability by Activating OncomiRs
Authors: Vernin Céline , Thenoz Morgan , Pinatel Christiane , Gessain Antoine , Gout Olivier , Delfau-Larue Marie-Hélène , Nazaret Nicolas , Legras-Lachuer Catherine , Wattel Eric , Mortreux Franck
Published: April 2023

Supplemental Figure 3. Validation of mRNA microarray data.
Supplementary Figure 4 from Development of Novel ADCs: Conjugation of Tubulysin Analogues to Trastuzumab Monitored by Dual Radiolabeling
Authors: Cohen Ruth , Vugts Danielle J. , Visser Gerard W.M. , Stigter-van Walsum Marijke , Bolijn Marije , Spiga Marco , Lazzari Paolo , Shankar Sreejith , Sani Monica , Zanda Matteo , van Dongen Guus A.M.S.
Published: April 2023

Biodistribution of 89Zr-trastuzumab. The 89Zr uptake of 89Zr-trastuzumab in A N87 and B JIMT-tumor bearing mice at 3, 24, 48 and 72 h after injection; data are presented as %ID/g {plus minus} SD.
Supplementary Figure S5 from Stress Response Protein Cirp Links Inflammation and Tumorigenesis in Colitis-Associated Cancer
Authors: Sakurai Toshiharu , Kashida Hiroshi , Watanabe Tomohiro , Hagiwara Satoru , Mizushima Tsunekazu , Iijima Hideki , Nishida Naoshi , Higashitsuji Hiroaki , Fujita Jun , Kudo Masatoshi
Published: April 2023

Figure S5. Representative immunostaining images of colonic mucosa of non-treated (DSS -), DSS-treated (DSS) and AOM+DSS-treated mice (AOM+DSS) using anti-Sox2 (A) and anti-Cirp(B) antibody. Scale bar, 100 microm.
Supplementary Figure S3 from Inhibition of Adaptive Immunity by IL9 Can Be Disrupted to Achieve Rapid T-cell Sensitization and Rejection of Progressive Tumor Challenges
Authors: Hoelzinger Dominique B. , Dominguez Ana Lucia , Cohen Peter A. , Gendler Sandra J.
Published: April 2023

Supplementary Figure S3. Tregs derived from IL-9ko mice are less functionally suppressive than WT Tregs.
Supplementary Figure S1 from Inhibition of Adaptive Immunity by IL9 Can Be Disrupted to Achieve Rapid T-cell Sensitization and Rejection of Progressive Tumor Challenges
Authors: Hoelzinger Dominique B. , Dominguez Ana Lucia , Cohen Peter A. , Gendler Sandra J.
Published: April 2023

Supplementary Figure S1. IL-9 is not a factor in TUBO and 4T1 mammary carcinoma growth.
Supplementary Figure S2 from Stress Response Protein Cirp Links Inflammation and Tumorigenesis in Colitis-Associated Cancer
Authors: Sakurai Toshiharu , Kashida Hiroshi , Watanabe Tomohiro , Hagiwara Satoru , Mizushima Tsunekazu , Iijima Hideki , Nishida Naoshi , Higashitsuji Hiroaki , Fujita Jun , Kudo Masatoshi
Published: April 2023

Figure S2. Association between Cirp and IL-17, Bcl-2, Bcl-xL or Sox2 in the colonic mucosa of patients with Crohn's disease (CD). Scatter plot of relative mRNA levels of Cirp and respective genes in human colonic mucosa.
Supplementary Figure Legends from Inhibiting DX2-p14/ARF Interaction Exerts Antitumor Effects in Lung Cancer and Delays Tumor Progression
Authors: Oh Ah-Young , Jung Youn Sang , Kim Jiseon , Lee Jee-Hyun , Cho Jung-Hyun , Chun Ho-Young , Park Soyoung , Park Hyunchul , Lim Sikeun , Ha Nam-Chul , Park Jong Sook , Park Choon-Sik , Song Gyu-Yong , Park Bum-Joon
Published: April 2023

Supplemental figure legends.
Supplementary Figure S1 from Oncoprotein HBXIP Modulates Abnormal Lipid Metabolism and Growth of Breast Cancer Cells by Activating the LXRs/SREBP-1c/FAS Signaling Cascade
Authors: Zhao Yu , Li Hang , Zhang Yingyi , Li Leilei , Fang Runping , Li Yinghui , Liu Qian , Zhang Weiying , Qiu Liyan , Liu Fabao , Zhang Xiaodong , Ye Lihong
Published: April 2023

The expression of HBXIP is positively correlated with that of FAS in clinical cancer tissues.
Supplementary table and figures 1-3 from The Polyamine Catabolic Enzyme SAT1 Modulates Tumorigenesis and Radiation Response in GBM
Authors: Brett-Morris Adina , Wright Bradley M. , Seo Yuji , Pasupuleti Vinay , Zhang Junran , Lu Jun , Spina Raffaella , Bar Eli E. , Gujrati Maneesh , Schur Rebecca , Lu Zheng-Rong , Welford Scott M.
Published: April 2023

Supplementary table and figures 1-3. Table 1: combined list of screen data identifying 10 genes that commonly sensitize cells to radiation when knocked down. S1: Western blot confirming knockdown of SAT1. S2: Expression of SAT1 in control and shSAT1 knockdown tumors grown orthotopically in nude mice from Figure 3C and D after sacrifice. S3: Flow cytometry sort of control (shGFP) and SAT1 knockdown cells for Figure 5C.
Supplementary Figure S3 from TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability
Authors: Pommier Roxane M. , Gout Johann , Vincent David F. , Alcaraz Lindsay B. , Chuvin Nicolas , Arfi Vanessa , Martel Sylvie , Kaniewski Bastien , Devailly Guillaume , Fourel Geneviève , Bernard Pascal , Moyret-Lalle Caroline , Ansieau Stéphane , Puisieux Alain , Valcourt Ulrich , Sentis Stéphanie , Bartholin Laurent
Published: April 2023

Inactivation of Tif1γ in HEK-293T and HepG2 cells rapidly results in cell cycle blockade in G2/M phases and mitotic catastrophe events.
Supplementary Figure S3 from Kinome-wide Functional Screen Identifies Role of PLK1 in Hormone-Independent, ER-Positive Breast Cancer
Authors: Bhola Neil E. , Jansen Valerie M. , Bafna Sangeeta , Giltnane Jennifer M. , Balko Justin M. , Estrada Mónica V. , Meszoely Ingrid , Mayer Ingrid , Abramson Vandana , Ye Fei , Sanders Melinda , Dugger Teresa C. , Allen Eliezer V. , Arteaga Carlos L.
Published: April 2023

Supplementary Figure S3. PLK1 knockdown decreases hormone-independent ER transcriptional activity.
Supplementary Movie 2 from Genetic Identification of SEMA3F as an Antilymphangiogenic Metastasis Suppressor Gene in Head and Neck Squamous Carcinoma
Authors: Doçi Colleen L. , Mikelis Constantinos M. , Lionakis Michail S. , Molinolo Alfredo A. , Gutkind J. Silvio
Published: April 2023

Supplementary Movies 2. SEMA3F induces rapid collapse of LECs (SEMA3F).
Supplementary Table S1 from Cables1 Complex Couples Survival Signaling to the Cell Death Machinery
Authors: Shi Zhi , Park Hae R. , Du Yuhong , Li Zijian , Cheng Kejun , Sun Shi-Yong , Li Zenggang , Fu Haian , Khuri Fadlo R.
Published: April 2023

Supplementary Table S1. 14-3-3y-associated proteins from A549 lung cancer cells.
Supplementary Figure S1 from Cables1 Complex Couples Survival Signaling to the Cell Death Machinery
Authors: Shi Zhi , Park Hae R. , Du Yuhong , Li Zijian , Cheng Kejun , Sun Shi-Yong , Li Zenggang , Fu Haian , Khuri Fadlo R.
Published: April 2023

Supplementary Figure S1. Correlation of Akt status with phosphorylation of Cables1 at pT44 and T150 in an A549 tumor xenograft mouse model.
Supplemental Figure 5 from Genetic Identification of SEMA3F as an Antilymphangiogenic Metastasis Suppressor Gene in Head and Neck Squamous Carcinoma
Authors: Doçi Colleen L. , Mikelis Constantinos M. , Lionakis Michail S. , Molinolo Alfredo A. , Gutkind J. Silvio
Published: April 2023

Supplementary Figure 5. Increased NRP2 expression correlates with poor prognosis in HNSCC.
Supplemental Figure 4 from Genetic Identification of SEMA3F as an Antilymphangiogenic Metastasis Suppressor Gene in Head and Neck Squamous Carcinoma
Authors: Doçi Colleen L. , Mikelis Constantinos M. , Lionakis Michail S. , Molinolo Alfredo A. , Gutkind J. Silvio
Published: April 2023

Supplementary Figure 4. Plexin D1 does not participate in SEMA3F signaling.
Supplemental References from Activation-Induced Cytidine Deaminase Contributes to Pancreatic Tumorigenesis by Inducing Tumor-Related Gene Mutations
Authors: Sawai Yugo , Kodama Yuzo , Shimizu Takahiro , Ota Yuji , Maruno Takahisa , Eso Yuji , Kurita Akira , Shiokawa Masahiro , Tsuji Yoshihisa , Uza Norimitsu , Matsumoto Yuko , Masui Toshihiko , Uemoto Shinji , Marusawa Hiroyuki , Chiba Tsutomu
Published: April 2023

Supplemental References
Supplementary Table S4 from IL13 Receptor α2 Signaling Requires a Scaffold Protein, FAM120A, to Activate the FAK and PI3K Pathways in Colon Cancer Metastasis
Authors: Bartolomé Rubén A. , García-Palmero Irene , Torres Sofía , López-Lucendo María , Balyasnikova Irina V. , Casal J. Ignacio
Published: April 2023

List of proteins involved in transport and co-immunoprecipitated with IL13Rα2
Supplemental Figure 1 from Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma
Authors: Cheng Hanyin , Terai Mizue , Kageyama Ken , Ozaki Shinji , McCue Peter A. , Sato Takami , Aplin Andrew E.
Published: April 2023

Supplementary Figure 1: Mutational status of UM cell lines and their response to trametinib.
Supplementary Figure S1 from Heparanase Enhances Tumor Growth and Chemoresistance by Promoting Autophagy
Authors: Shteingauz Anna , Boyango Ilanit , Naroditsky Inna , Hammond Edward , Gruber Maayan , Doweck Ilana , Ilan Neta , Vlodavsky Israel
Published: April 2023

Supplementary Figure S1. Heparanase enhances autophagy.
Supplementary Table S1 from Targeting the miR-221–222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma
Authors: Zhao Jian-Jun , Chu Zhang-Bo , Hu Yu , Lin Jianhong , Wang Zhongqiu , Jiang Meng , Chen Ming , Wang Xujun , Kang Yue , Zhou Yangsheng , Chonghaile Triona Ni , Johncilla Melanie E. , Tai Yu-Tzu , Cheng Jin Q. , Letai Antony , Munshi Nikhil C. , Anderson Kenneth C. , Carrasco Ruben D.
Published: April 2023

Supplementary Table S1. MM patients' information.
Supplementary Figure S3 from Targeting the miR-221–222/PUMA/BAK/BAX Pathway Abrogates Dexamethasone Resistance in Multiple Myeloma
Authors: Zhao Jian-Jun , Chu Zhang-Bo , Hu Yu , Lin Jianhong , Wang Zhongqiu , Jiang Meng , Chen Ming , Wang Xujun , Kang Yue , Zhou Yangsheng , Chonghaile Triona Ni , Johncilla Melanie E. , Tai Yu-Tzu , Cheng Jin Q. , Letai Antony , Munshi Nikhil C. , Anderson Kenneth C. , Carrasco Ruben D.
Published: April 2023

Supplementary Figure S3. Changes in PUMA mRNA expression induced by V-miR-221-222-GFP and V-as-miR-221-222-GFP.
Supplementary Figure S7 from Proteolysis of EphA2 Converts It from a Tumor Suppressor to an Oncoprotein
Authors: Koshikawa Naohiko , Hoshino Daisuke , Taniguchi Hiroaki , Minegishi Tomoko , Tomari Taizo , Nam Sung-Ouk , Aoki Mikiko , Sueta Takayuki , Nakagawa Takashi , Miyamoto Shingo , Nabeshima Kazuki , Weaver Alissa M. , Seiki Motoharu
Published: April 2023

Supplementary Figure S7. Detection of N-terminal EphA2 fragments released from cancer cells.
Supplementary Figure S4 from Proteolysis of EphA2 Converts It from a Tumor Suppressor to an Oncoprotein
Authors: Koshikawa Naohiko , Hoshino Daisuke , Taniguchi Hiroaki , Minegishi Tomoko , Tomari Taizo , Nam Sung-Ouk , Aoki Mikiko , Sueta Takayuki , Nakagawa Takashi , Miyamoto Shingo , Nabeshima Kazuki , Weaver Alissa M. , Seiki Motoharu
Published: April 2023

Supplementary Figure S4. Effect of MT1-MMP on EphA2 downstream signaling.
Supplementary Figure S1 from Proteolysis of EphA2 Converts It from a Tumor Suppressor to an Oncoprotein
Authors: Koshikawa Naohiko , Hoshino Daisuke , Taniguchi Hiroaki , Minegishi Tomoko , Tomari Taizo , Nam Sung-Ouk , Aoki Mikiko , Sueta Takayuki , Nakagawa Takashi , Miyamoto Shingo , Nabeshima Kazuki , Weaver Alissa M. , Seiki Motoharu
Published: April 2023

Supplementary Figure S1. Expression of EphA2 and MT1-MMP in human cancer cell lines.
Supplementary Figure S3 from Vacuolar-ATPase Inhibition Blocks Iron Metabolism to Mediate Therapeutic Effects in Breast Cancer
Authors: Schneider Lina S. , von Schwarzenberg Karin , Lehr Thorsten , Ulrich Melanie , Kubisch-Dohmen Rebekka , Liebl Johanna , Trauner Dirk , Menche Dirk , Vollmar Angelika M.
Published: April 2023

Supplementary Figure S3. Archazolid has no influence on HIF1α mRNA levels in MDA-MB-231 cells.
Supplementary Figure 7 from TUBB3/βIII-Tubulin Acts through the PTEN/AKT Signaling Axis to Promote Tumorigenesis and Anoikis Resistance in Non–Small Cell Lung Cancer
Authors: McCarroll Joshua A. , Gan Pei Pei , Erlich Rafael B. , Liu Marjorie , Dwarte Tanya , Sagnella Sharon S. , Akerfeldt Mia C. , Yang Lu , Parker Amelia L. , Chang Melissa H. , Shum Michael S. , Byrne Frances L. , Kavallaris Maria
Published: April 2023

A) A graph showing a decrease in ÃŽÂ²III-tubulin mRNA expression in A549 NSCLC cells stably expressing ÃŽÂ²III-tubulin shRNA (pRS/ÃŽÂ²IIISH61) vs. cells stably expressing control shRNA (pRS/CtrlSH27). B) Representative western blot demonstrating potent knockdown of ÃŽÂ²III-tubulin protein expression in A549 NSCLC cells stably expressing ÃŽÂ²III-tubulin shRNA (pRS/ÃŽÂ²IIISH61) vs. cells stably expressing control shRNA (pRS/CtrlSH27). GAPDH was used a protein loading control, n = 3 experiments.
Supplementary Figure S2 from Cell–Cell Adhesion and Cytoskeleton Tension Oppose Each Other in Regulating Tumor Cell Aggregation
Authors: Saias Laure , Gomes Aurélie , Cazales Martine , Ducommun Bernard , Lobjois Valérie
Published: April 2023

Supplementary Figure S2. E-cadherin expression in HCT116, MCF-7 and MDA-MB-231 cell lines. Bottom, E-cadherin fluorescence (E-Cadh). Top, merged images of E-cadherin fluorescence (green) and DAPI fluorescence (blue) staining of the nuclei. HCT116 cells were seeded on glass slides 3 days before immunofluorescent staining (Bar, 50 µm). MCF7 and MDA-MB-231 spheroids were fixed after 7 days in culture and immunofluorescent staining was performed on frozen sections (Bar, 100 µm).
Supplementary Table S6 from Metastatic Competence Can Emerge with Selection of Preexisting Oncogenic Alleles without a Need of New Mutations
Authors: Jacob Leni S. , Vanharanta Sakari , Obenauf Anna C. , Pirun Mono , Viale Agnes , Socci Nicholas D. , Massagué Joan
Published: April 2023

Supplementary Table S6. Primers used in this study are listed.
Supplementary Table S5 from Metastatic Competence Can Emerge with Selection of Preexisting Oncogenic Alleles without a Need of New Mutations
Authors: Jacob Leni S. , Vanharanta Sakari , Obenauf Anna C. , Pirun Mono , Viale Agnes , Socci Nicholas D. , Massagué Joan
Published: April 2023

Supplementary Table S5. Genes for which a positive correlation was found between copy number variation and gene expression are listed.