bluuebunny/crossref_metadata_2025 huggingface dataset:
LEGIONELIOZĖ: SUNKIOS PNEUMONIJOS ATVEJIS
Authors: Girdžiūnienė Rasa , Jakovlevaitė Goda
Published: April 2021

Straipsnyje aptariama 21 metų vyro, sirgusio legioneliozine pneumonija, atvejis. Pacientas karščiavo, kosėjo, skaudėjo dešinįjį šoną. Po 2 dienų atsiradus dusuliui, kreipėsi į priėmimo skyrių. Rentgenologiškai rastas sumažėjęs oringumas, polisegmentinės infiltracijos. Legionella pneumophilla antigeno nustatymo tyrimas imunochromatografiniu metodu – teigiamas. Pacientui taikyta efektyvi antibiotikoterapija. Straipsnyje pateikiama literatūros apžvalga apie šią retai aptinkamą ligą bei jos kliniką, diagnostiką ir gydymą.
SKIRTINGŲ REABILITACIJOS METODŲ POVEIKIS VAIKŲ, SERGANČIŲ CEREBRINIU PARALYŽIUMI, MOTORINĖMS FUNKCIJOMS BEI EISENAI
Authors: Juškėnienė Giedrė , Šidlauskienė Aurelija , Raistenskis Juozas , Žižienė Jurgita , Daunoravičienė Kristina
Published: April 2021

Cerebrinis paralyžius (CP) susijęs su besivystančių smegenų pažeidimu ir apima grupę pastovių judėjimo ir laikysenos vystymosi sutrikimų, lemniačių kasdienio aktyvumo apribojimą [1,2]. Ši liga dažniausiai pasireiškia apatinių galūnių silpnumu bei sutrikusia eisena [3,4]. Tai viena iš dažniausių neįgalumo priežasčių vaikystėje [5]. Kineziterapija yra pagrindinė vaikų, sergančių CP, reabilitacijos procedūra, kurios metu stiprinant galūnių raumenis koreguojama eisena bei pagerėja vaikščiojimo funkcija, tačiau iki šiol nėra sukurta standartinių CP reabilitacijos programų [4]. Literatūroje nurodoma, kad galima nustatyti eisenos nuokrypio ir klinikinės išraiškos sąsajas, identifikuojant atskiras eisenos ciklo fazes. Šių žinių pritaikymas praktikoje galėtų lemti geresnį supratimą apie eisenos sutrikimų patofiziologiją bei pagerinti individualaus gydymo plano sudarymą [6].
JUOSMENS – DUBENS SRITIES TIESIMO IR ROTACINIŲ JUDESIŲ KONTROLĖS TESTŲ PATIKIMUMO TYRIMAS
Authors: Kiškūnaitė Monika , Muntianaitė Inga , Sinkevičiūtė Viltė , Indriūnienė Jurga
Published: April 2021

Tikslas – įvertinti juosmens – dubens srities tiesimo ir rotacinių judesių kontrolės testų patikimumą tarp dviejų tyrėjų. Tyrimo metodai. Momentinis tyrimas atliktas Vilniaus universiteto Medicinos fakultete. Tyrime dalyvavo 50 tiriamųjų, kuriuos vertino du tyrėjai ir buvo lyginamas jų sutariamumas. Tyrimo metu buvo vertinama juosmens – dubens srities tiesimo ir rotacinių judesių kontrolė, atliekant judesių kontrolės testus, kurie vertinami: 1 – atliko, 0 – neatliko.

Rezultatai. Vertinant pirmajam tyrėjui, geriausiai buvo atliekamas šoninis liemens lenkimas, o prasčiausiai – blauzdos tiesimo testas. Vertinant antrajam tyrėjui, geriausiai buvo atliekamas padėties keturpėsčia (pirmyn) testas, o prasčiausiai – kelių siūbavimas bei šlaunies rotacija, gulint ant pilvo. Analizuojant dviejų vertintojų sutariamumą, nebuvo testų, kurių sutariamumas būtų silpnas [κ = 0,21-0,40], devynių testų sutariamumas buvo vidutinis [κ = 0,41-0,60], vieno geras [κ = 0,61-0,80] ir vieno labia geras [κ = 0,81-0,99]. Geriausias sutariamumas nustatytas testuojant šlaunies atitraukimą, gulint ant šono.

Išvados. Visų juosmens – dubens srities tiesimo ir rotacinių judesių kontrolės testų vertinimo sutariamumas laikomas patikimu klinikiniam naudojimui. Cohen’s kappa koeficientas svyravo nuo 0,438 iki 0,865, o procentinis sutariamumas viršijo 70 procentų. Geras ir labai geras [κ = 0,61-0,99] dviejų tyrėjų sutariamumas nustatytas kelių siūbavimo ir šlaunies atitraukimo testams.
SKIRTINGŲ KINEZITERAPIJOS VEIKSNIŲ POVEIKIS RAUMENŲ FUNKCIJOMS IR AEROBINIAM METABOLIZMUI, ESANT APATINĖS NUGAROS DALIES STUBURO IŠVARŽAI
Authors: Trinkūnas Domas , Dadelienė Rūta
Published: April 2021

Tyrimo tikslas – įvertinti skirtingų kineziterapijos veiksnių poveikį raumenų funkcijoms ir jų aerobiniam metabolizmui, esant apatinės nugaros dalies stuburo išvaržai.

Tyrimo metodai. Tyrime dalyvavo 38 asmenys, turintys apatinės nugaros dalies stuburo išvaržą. Prie paskirtos 20 minučių trukmės kineziterapijos programos papildomai I grupės (n=19) dalyviams buvo skiriami 20 minučių trukmės dinaminiai pratimai, o II grupės (n=19) dalyviams buvo skiriami 20 minučių trukmės statiniai pratimai, turintys biologinį grįžtamąjį ryšį. Abiejų grupių treniravimo programos truko šešias savaites, tris kartus per savaitę. Tyrimo metu buvo vertintas raumenų aerobinis metabolizmas, naudojant „Moxy“ raumenų oksimetrą, raumenų įsitempimo lygis, naudojant „Kinesis“ elektromiografijos prietaisą. Raumenų funkcijos vertintos išmatavus pasiekiamą judesio amplitudę, amplitudžių matuokliu „Mobee Med“, bei atstumas nuo mentės vidinio krašto iki stuburo keteros vidurio taško, buvo vertinamas centimetrine juostele. Duomenų analizė atlikta naudojant statistinės analizės Microsoft Excel 2016 ir IBM SPSS Statistics 25 programas.

Tyrimo rezultatai. Judesių amplitudės asimetrijos sumažėjimas buvo stebimas tik po dinaminių pratimų programos (p<0.001). Dinaminių pratimų grupėje raumens aktyvumo asimetrija sumažėjo tik viduriniame trapeciniame raumenyje (p<0,05), o statinių pratimų, turinčių biologinį grįžtamąjį ryšį, grupėje raumens aktyvumo skirtumas sumažėjo viduriniame trapeciniame, bei didžiajame sėdmens raumenyse. Statinių pratimų, turinčių biologinį grįžtamuąjį ryšį, programa daugiau sumažino didžiojo sėdmens raumenų deguonies kiekio disbalansą (p<0,001), nei dinaminių pratimų programa.

Išvados. Dinaminių kineziterapijos pratimų programa turėjo reikšmingą poveikį judesių amplitudžių asimetrijos sumažėjimui. Statinių kineziterapijos pratimų, turinčių biologinį grįžtamąjį ryšį, metodika daugiau padidino bendrą raumens aktyvumą ir labiau sumažino raumenų aktyvumo asimetriją, nei dinaminiai kineziterapijos pratimai. Statinių kineziterapijos pratimų, turinčių biologinį grįžtamąjį ryšį, metodika daugiau sumažino raumens aerobinio metabolizmo disbalansą tarp raumens kairiosios ir dešiniosios pusių, nei dinaminių kineziterapijos pratimų naudojimas.
LIETUVOS OPTOMETRININKŲ PROFESINIO TOBULINIMO IR OPTOMETRINĖS PRIEŽIŪROS PASLAUGŲ PLĖTROS POREIKIO ĮVERTINIMAS
Authors: Kačergienė Vaida , Kutkauskienė Jelena , Galgauskas Saulius
Published: April 2021

Darbo tikslas. Įvertinti Lietuvos optometrininkų profesinio tobulinimo ir optometrinės priežiūros paslaugų plėtros poreikį.

Darbo metodika. Kiekybiniam tyrimui atlikti naudotas anketinės apklausos metodas. Tyrimo priemone pasirinktas elektroninis klausimynas, į kurį respondentams išsiųsta nuoroda elektroniniu paštu. Tiriamųjų grupę (134 respondentai) sudarė optometrininkai, registruoti Lietuvos optometrininkų asociacijoje. Anketų grįžtamumas siekė 64,2 proc., t.y. iš viso buvo užpildytos ir pateiktos analizei 86 anketos. Analizei pateiktose anketose: 48,8 proc. respondentų nurodytas darbo stažas buvo 6–10 m., o 82,6 proc. – pagrindinė darbo vieta buvo didmiestis (Vilnius, Kaunas, Klaipėda). SPSS programinė įranga (23.0 versija) panaudota duomenų statistinei analizei. Rezultatų skirtumai laikyti statistiškai reikšmingais, kai p < 0,05.

Rezultatai. Nustatyta, kad 50 proc. Lietuvos optometrininkų pageidautų dalyvauti profesinio tobulinimo renginiuose 3–4 kartus per metus, o 27,9 proc. – 5 ir daugiau kartų per metus. Svarbiausia optometrininkų profesinio tobulinimo sritis yra akių ligos, jų atpažinimas ir regos korekcija (83,7%). Identifikuota pagrindinė, didžiausios plėtros reikalinga paslauga – akių ligų ir patologijų nustatymas (64,1%). Respondentų pasiskirstymo pagal naudotus kintamuosius ir darbo stažą palyginimas atskleidė, jog statistiškai reikšmingai skyrėsi dalyvavimo optometrijos profesinio tobulinimo renginiuose poreikis bei tobulinimo sritys, susijusios su sausa akimi ir jos priežiūra, miopija ir jos korekcija, presbiopija ir jos korekcija bei kontaktiniais lęšiais (p < 0,05). Palyginimas, naudojant gyvenvietės tipą vietoje darbo stažo, parodė, kad statistiškai reikšmingai skyrėsi tik tobulinimo sritis, susijusi su vaikų regos sutrikimų ypatumais bei šios optometrinės priežiūros paslaugos: regos korekcijos kortelės akiniams išrašymas, siuntimo gydytojui oftalmologui išrašymas, akių ligų ir patologijų nustatymas bei diagnostinių priemonių, priskiriamų medicinos prekėms, naudojimas (p < 0,05).

Išvados. Dėl nepakankamos profesinės darbo patirties Lietuvos optometrininkų profesinio tobulinimo poreikis yra gana aukštas, ypač sričiai, susijusiai su akių ligomis, jų atpažinimu ir regos korekcija. Lietuvoje didžiausias optometrijos paslaugų plėtros poreikis tenka akių ligų ir patologijos nustatymui.
MELANOMA SERGANČIŲ PACIENTŲ LIGOS IR GYVENSENOS KONTROLĖ
Authors: Nebilevičiūtė Monika , Kielė Viktorija , Kutkauskienė Jelena
Published: April 2021

Per pastaruosius tris dešimtmečius melanomos paplitimas pasaulyje padidėjo daugiau nei dvigubai. Melanoma sudaro mažiau nei 5 proc. visų odos vėžio atvejų, tačiau mirtingumas nuo jos siekia daugiau kaip 70 proc. Tarp odos navikų [2]. Ankstyvas diagnozavimas ir efektyvus ligos valdymas, rūpinimasis pacientais, jų mokymas ir įgalinimas – tai vieni pagrindinių melanomos terapijos aspektų, už kuriuos atsakingi slaugytojai [3,4]. Onkologijos slaugytojas vaidina svarbų vaidmenį mokant, įgalinant pacientus ir jų artimuosius odos vėžio valdymo bei prevencijos tema, gali dirbti pacientų ir jų artimųjų mentoriumi, skatinti dalyvavimą odos vėžio prevencijos tyrimuose. Bendradarbiaudamas su gydytojais, pacientais ir jų artimaisiais, slaugytojas gali užkirsti kelią galimiems odos vėžio atvejams, o susirgus – įgalinti pacientus valdyti savo ligą [5].

Tyrimo tikslas – išanalizuoti slaugytojo vaidmenį ir veiksnius, įgalinančius melanoma sergančius pacientus kontroliuoti savo ligą.

Rezultatai. Atliktos tiriamosios apžvalgos metu išsiaiškinta, kad slaugytojų vaidmuo pasaulyje yra itin svarbus, nes jie atlieka ne tik su slauga susijusias funkcijas. Slaugytojai kryptingai dirba, kad melanoma sergantys pacientai suprastų savo diagnozę, gydymo rekomendacijas ir dalyvavimo klinikiniuose tyrimuose svarbą [6]. Pacientų mentoriai turi išskirtines galimybes pagerinti kultūrinę vėžio priežiūros kompetenciją, atsižvelgiant į jų ryšį su pacientais ir įgalinant juos kontroliuoti savo ligą, o mentorių funkcijų vykdymo strategijos turėtų būti įtrauktos į visų sveikatos priežiūros specialistų mokymus ir kvalifikacijos kėlimo kursus [7].
EFFECT OF DIFFERENT ADMINISTRATION METHODS OF VITAMIN AD3E TO HATCHING EGGS AND SUPPLEMENT IT WITH DRINKING WATER ON HATCHABILITY TRAITS AND POST HATCH PERFORMANCE AND BIOCHEMICAL PARAMETER OF BROILER
Authors: Hassan W. H. , Tayeb I. T.
Published: April 2021

This study was conducted at the Badi Hatchery and poultry house / department of animal production / College of Agriculture engineering science/ University of Duhok. The aim of study was to investigate the effect of different administration methods of vitamin AD3E to hatching eggs on hatchability and post hatch productive performance and some physiological parameter of broiler. A total of one thousand and two hundred fifty (1250) hatched eggs were distributed into five groups each groups 250 eggs. The experimental treatments were as the follow: T1 (Control), T2 (sham control)(injected with 0.1 ml normal saline), T3 (injected with 0.1 ml of vitamin AD3E dissolved in 5 ml of vitamin in 1 ml of water) T4 (Spraying vitamin AD3E 1 ml /L water), T5 (Dipping vitamin AD3E 1 ml /L water). During the rearing period, each treatment divided into 2 group of replications, (5 replication) for each group that is from one treatment exactly. First 5 five replications (R1-R5) for each treatment given different doses of vitamin at different rearing age via drinking water and other 5 five replications (R6-R10) were drink normal water throughout the rearing period which is at least 5 weeks. Weekly Live body weight, body weight gain, feed consumption, feed conversion ratio, mortality percentage, Production index were recorded, (Total protein, glucose and cholesterol), blood serum titer for testing the immunity of chicken against diseases Newcastle (ND) and Gumboro, infectious bronchitis (IB). The overall data shows the following results: - In hatching stage there were significant affect in chick weight and chick to egg ratio and in rearing stage live body weight, body weight gain, feed conversion ratio, production index, serum glucose, Newcastle Gambaro and infectious bronchitis disease.
REASONS RELATED TO THE DETERIORATION OF POULTRY INDUSTRY FOR BROIERS IN THE MIDDLE AND SOUTHERN REGION OF IRAQ
Authors: AL- Ani G. A.A. , AL- Badri A. A.N.
Published: April 2021

The objective of this research is to identify the reasons related to deterioration of the poultry industry for broilers in the middle and southern regions of Iraq. In order to achieve the research goals a questionnaire form consists of two parts was designed, the first part included a quadrilateral scale of (54) items distributed in to eight base fields. The second part included a five scales with (20) items. The results showed that, the imported product field achieved the first position among the reasons that related to the deterioration of poultry industry for broilers, which achieved the highest weighted average by 2.8 degree and a weight percentage of 93.3%. While the direction field of the broilers breeders was ranked the last position among the reasons that related to deterioration in poultry industry for broilers, which achieved the lowest weighted average which is 2.6 degree  with weight of 86.6%. The results also, showed that the item start working with the integrated production companies in the poultry industry to produce poultry meat was ranked in the first position among the proposed solutions from the broilers breeders' points of view to face the deterioration of the poultry industry for broilers, which ranked the highest weighted average of 4.9 degrees and a percentage weight of 98%. Finally, the item Control the importer's hatching eggs was ranked the last position among the proposed solutions from the broilers breeders' points of view to face the deterioration in the poultry industry for broilers, which achieved the lowest weighted average by (4.5) degrees and a percentage weight of 90%.
THE POTENTIAL USE OF Ca(NO3)2 TO IMPROVE SALINITY TOLERANCE IN DATE PALM (Phoenix dactylifera L.)
Authors: Alturki Saleh M.
Published: April 2021

The study was conducted to investigate the impact of Ca(NO3)2 on  different levels of salt-stress in date palm. Three-years-old date palm plants were subjected to four NaCl levels: 50, 100, 150 and 200 mM. The saline solutions were supplemented with 0, 5, 10 and 20 mM Ca(NO3)2. The combined NaCl/Ca(NO3)2 treatments were conducted over a period of 10 weeks. Control plants were only subjected to the four salinity levels with no Ca (NO3)2 addition. Results showed an inhibitory effect of salinity on almost all plants' parameters under investigation, mainly the accumulation of ions such as N, K, Ca, plant dry weight, chlorophyll and net photosynthesis rate. Addition of Ca (NO3)2 in the solution was more beneficial when added in a moderate concentration (10 mM) compared to lower (5 mM) and higher (20 mM) under all salinity levels. The addition of 10 mM Ca (NO3)2 noticeably enhanced chlorophyll content under 50 mM Na Cl (2.5 mg/100 cm2) and 150 mM NaCl (2 mg/100 cm2). In addition, 10 mM Ca (NO3)2 reduced the accumulation of Na and Cl in plant parts. For instance, in trees subjected to 10 mM Ca (NO3)2, Cl content in leaves and stems under 50 mM Na Cl were 0.23% and 0.65%, respectively. On the other hand, Cl content under 100 mM Na Cl and 200 mM Na Cl were lower compared to their corresponding control treatments. It seems that the use of Ca (NO3)2 had ameliorative effects on salt-stressed date palm plants when used with moderate concentrations.
TEENAGE PREGNANCY – ANALYSE THE DETERMINANTS AND SOCIODEMOGRAPHIC FACTORS
Authors: Thawal Yogesh , Patvekar Meenal M. , Jain Shayari , Kolate Dipak Suresh , Katakdhond Shriraj , Medam Sailaja
Published: April 2021

Background: “Teenage” or “Adolescence” is the transition phase from childhood to adulthood. Teenage pregnancy has emerged as one of the
major social & nancial issue in recent years with great impact on feto-maternal health & become challenge to obstetrician.
Objectives: The aim of this study is to analyse determinants, risk factors , sociodemographic factors in the teenage pregnancies & it's adverse
consequences.
Materials & Methods: This observational Study was conducted at Dr DY Patil Medical College, Hospital and Research Institute, Pimpri, Pune .
Data collected from teenage pregnant females (age more than 18years and less than 20 years) who are willing to participate in this study.
Results: The current study evaluated the adverse impact of teenage pregnancies on maternal and neonatal health outcomes with emphasis on socioeconomic factors, risk factors and complications of such pregnancies. Among the total 205 cases of teenage pregnancy, 71.22% cases were between
19-20 years and 28.78% were between 18-19 years. Most of the mothers around 42.93% studied only up to primary school whereas 31.17% were
uneducated.
Most of the mothers were in the upper lower and the lower scale of socio-economic status based on the Kuppuswami Classication. Many were
from rural areas due to lack of awareness and minimal education about teenage pregnancies. Anaemia (16.58%) was commonest risk factor for
complications in teenage pregnancies.
Conclusion: Teenage pregnancies are associated with increased health care expenditure and adversely affect the socio-economic status as most of
the subjects belong to lower socio-economic strata and were uneducated. Hence, it is vital to prevent teenage pregnancies as far as possible by good
education , creating awareness about it and as well through government regulations.
CLINICAL STUDY OF RETINAL CHANGES OF DIABETIC PATIENTS UNDERGONE CATARACT SURGERY WITH PRE-EXISTING DIABETIC RETINOPATHY AND WITHOUT PRE-EXISTING DIABETIC RETINOPATHY IN A TERTIARY CENTER OF WEST BENGAL.
Authors: Najnin Rhine , Bala Bivas
Published: April 2021

Aim: The aim of this study was evaluation and compare the visual outcomes after cataract surgery in diabetic and non-diabetic patients: patients
with and without diabetic retinopathy; assessment of post-operative complications after cataract surgery in diabetics compared to nondiabetics;
and analysis of increment in central foveal thickness using optical coherence tomography, after cataract surgery.
Methods: This Institutional based Observational study was done at Outpatient department, Indoor Department and Special retina Clinic in R. G.
Kar Medical College and Hospital, Kolkata over the Period of January 2019 to June 2020. This study included 125 diabetic patients with pre -
existing diabetic retinopathy and 125 no pre-existing diabetic retinopathy controls. After complete ophthalmological examination, all subject
undergone for cataract surgery. Post-operative visual acuity, intra or post-operative complication and change in subfoveal macular thickness
recorded in a predesigned chart and subsequently analysed.
Results: A total of 250 eyes were included in this study of them 125 were with diabetic retinopathy and 125 were without diabetic retinopathy
respectively. There were 89 eyes with mild NPDR, 32 with moderate NPDR and 4 with severe NPDR respectively. Male female ratio was 1.7: 1.
Most of the patients were at 50-70 years age group. Patients with uncontrolled baseline glycosylated haemoglobin level (HbA1c<7) was found to
be a major confounding factor as far as post-op visual recovery was concerned. Common post-operative complications after cataract surgery were
transient corneal oedema, Descemet's fold, hyphaema, iritis, misshapen pupil and pigment deposit on IOL respectively. Descemet's membrane
folds being the most frequent complication, however the difference was not statistically signicant. In our study, increase in central foveal
thickness was seen in both the groups, 6 months after cataract surgery
Efficient Online Scheduling of Electric Vehicle Charging Using a Service-Price Menu
Authors: Mathioudaki Angeliki , Tsaousoglou Georgios , varvarigos Emmanouel , Fotakis Dimitris
Published: April 2021

Along with high penetration of Electric Vehicles (EVs), charging stations are required to service a large amount of charging requests while accounting for constraints on the station's peak electricity consumption. To this end, a charging station needs to make online charging scheduling decisions often under limited future information. An important challenge relates to the prioritization of EVs that have unknown valuations for different levels of charging services. In this paper, we take into consideration the inability of EV users to express these valuations in closed-form utility functions. We consider a paradigm where a menu of possible charging schedules and corresponding prices is generated online. By letting the EV users pick their most preferable menu option, the proposed algorithm commits on each EV's charging completion time upon its arrival, achieves a near optimal total weighted charging completion time, and prevents the users from strategically misreporting their preferences, while offering a practical and implementable solution to the problem of EVs - charging station interaction.
Element Edge Based Discretization for TCAD Device Simulation
Authors: Sanchez Juan , Chen Qiusong
Published: April 2021

Technology computer-aided design (TCAD) semiconductor device simulators solve partial differential equations (PDE) using the finite volume method (FVM), or related methods. While this approach has been in use over several decades, its methods continue to be extended, and are still applicable for investigating novel devices. In this paper, we present an element edge based (EEB) FVM discretization approach suitable for capturing vector-field effects. Drawing from a 2D approach in the literature, we have extended this method to 3D. We implemented this method in a TCAD semiconductor device simulator, which uses a generalized PDE (GPDE) approach to simulate de- vices with the FVM. We describe how our EEB method is compatible with the GPDE approach, allowing the modeling of vector effects using scripting. This method is applied to solve polarization effects in a 3D ferro capacitor, and a 2D ferroelectric field-effect transistor. An example for field- dependent mobility in a 3D MOSFET is also presented.
THE CLAUSE COMPLEX CONSTRUCTIONS REALISED IN THE SHORT STORY ENTITLED “THE WITCH’S BREW”
Authors: Sarip Sri Kurnia , Hidayat Yusuf
Published: April 2021

Systemic Functional Linguistics (SFL) is the choice of analysis theory offering the effective tools to analyse the language difficulties and vagueness. One of the systemic analysis tools is clause complex which can simplify the structural and grammatical meanings of the analysed texts through the use of taxis systems and logico-semantic relations (Sagheer Eid, 2016). The proposed study is aimed at analysing systemic functional analysis of clause complex realised in a short story adopting Hallidayan linguistics perspective. The short story is taken from the collection of short stories entitled “The Whispering Knights” by Clare West. From the aforementioned short stories collection, the writers take a short story entitled “The Witch’s Brew” written by Penelope Lively. By means of a descriptive study under Systemic Functional Linguistics theory as suggested by Halliday & Matthiessen (2014), the writers employ the analysis of taxis systems which cover elaboration, extension, and enhancement. Besides, logico-semantic relation is also analysed which covers projection and expansion. The findings reveal that there are 158 clause complexes which consist of 58 clause complexes of parataxis which are realized 37%, and 40 clause complexes of hypotaxis which are realised 25.3%. In conclusion, the short story is written by the dominant of parataxis then hypotaxis constructions.
Pengaruh Beda Metode Pemasakan Dalam Pembuatan Tepung Limbah Ikan Nila Merah Terhadap Kandungan Nutrien
Authors: Dughita Putri Awaliya , Respati Adib Norma , Awalokta Kusuma Andri Haryono , Hakim Abdul
Published: April 2021

Tujuan dari penelitian ini untuk mengetahui pengaruh beda metode pemasakan terhadap kandungan nutrien tepung limbah ikan nila merah. Metode pemasakan yang digunakan pada penelitian yaitu T0 : Tepung limbah ikan nila merah tanpa perlakuan (kontrol) , T1 : Tepung limbah ikan nila merah dengan perlakuan perebusan, T2 : Tepung limbah ikan nila merah tanpa perlakuan pengukusan. Uji yang dilakukan menggunakan uji proksimat dengan variabel yang diamati yaitu kadar air, kadar abu, kadar protein dan kadar lemak. Hasil penelitian diperoleh nilai rata-rata uji proksimat tepung limbah ikan nila merah dengan metode pemasakan T0, T1 dan T2 berturut-turut adalah kadar air 6.42%, 8,38%, 8,70%, kadar abu 9,62%, 5,22%, 3,52%, kadar protein 60,10%, 55,30%, 58,80%, dan kadar lemak 14,60%, 9,45%, 5,80%. Kesimpulan bahwa tepung limbah ikan nila merah dengan metoda pemasakan T2 yaitu dengan metoda pemasakan pengukusan memiliki kandungan protein terbanyak.
Glukosa Darah dan Recovery Tubuh Ternak Kambing Perah yang Disuplementasi Mineral Organik dan Tepung Kulit Bawang Putih Pada Pakannya
Authors: Rayhan Muhammad , Prayitno Caribu Hadi , Subagyo Yusuf
Published: April 2021

Pengaruh pemberian mineral organik dan tepung kulit bawang putih yang mengandung polifenol salah satunya adalah allisin dapat menghambat kerja enzim HMG-CoA pada bakteri Archea rumen, sehingga terjadi H2 untuk pembentukan gas methan dialihkan kearah pembentukan propionat. Propionat sebagai prekusor pembentuk glukosa darah. Peningkatan propionat memberikan efek pada penurunan asetat. Asetat merupakan prekusor pembentuk kolesterol darah. Allisin juga dapat menghambat superoksidasi, sehingga tidak terjadi kerusakan membran sel dan dapat mempertahankan hemoglobin dalam darah. Keseimbangan terjadi terhadap kadar glukosa darah dan recovery tubuh ternak akan membaik. Pada ternak yang sedang bunting sering terjadi negative energy balance. Penelitian ini bertujuan untuk mengkaji pengaruh pemberian mineral organik dan tepung kulit bawang putih pada pakan kambing perah terhadap glukosa darah dan recovery tubuh. Materi yang digunakan dalam penelitian adalah kambing Jawa Randu induk bunting laktasi kedua sebanyak 15 ekor. Perlakuan yang diberikan yaitu penambahan tepung kulit bawang putih 30 ppm; Cr organik 1,5 ppm; Se organik 0,3 ppm dan Zn lisinat 40 ppm. Perlakuan yang diujicobakan yaitu R0 terdiri atas Pakan kontrol (Hijauan dan Konsentrat perbandingan 70:30). R1 terdiri ataspakan R0 + Tepung kulit bawang putih (Allium sativum) 30 ppm. R2 terdiri atas pakan R1 + Mineral Organik ( Se 0,3 ppm, Cr 1,5 ppm, Zn 40 ppm). Data dianalisis menggunakan analisis variansi dan dilanjutkan uji LSD. Hasil penelitian menunjukkan bahwa suplementasi tepung kulit bawang putih dan mineral organik pada pakan kambing perah tidak  berpengaruh nyata (P>0,05) terhadap kadar glukosa darah dan recovery tubuh.
GLICOSÍMETRO DIGITAL APLICADO A ANÁLISE DE AÇÚCAR REDUTOR EM POLPA DE FRUTAS
Authors: Silva de Souza Tércio da , Santos de Oliveira Jessika , Cindra de Souza Luiz Claudio
Published: April 2021

A análise de açúcares em alimentos é de suma importância no controle da qualidade dos produtos, sendo estes responsáveis pelo flavor, cor e textura. Em polpas de frutas a doçura é resultante da proporção entre a frutose, glicose e a sacarose, estes possuem poder adoçante diferenciado e definem o sabor final do produto. Existe uma ampla lista de técnicas e métodos oficiais capazes de determinar a concentração de açúcares em amostras de alimentos, contudo em sua maioria são de custo levado, geram grande volume de resíduos e seus resultados são demorados. Neste trabalho, propôs-se desenvolvimento uma metodologia para quantificação de açúcares redutores (AR) em amostras de polpa de frutas com glicosímetro digital “On Call Plus®”. A adaptação e validação da metodologia consistiram na construção de curva de calibração com padrões de glicose e verificação do efeito da interferência de outros açúcares na quantificação do teor de glicose; análise de amostras de polpa de fruta com glicosímetro digital e comparação com método de referência ADNS (Ácido 3,5-dinitrosalicílico), e por fim, o tratamento dos dados e avaliação dos parâmetros de validação para metodologia. O uso do glicosímetro digital foi validado, revelando-se rápido, seguro, de baixo custo, relativamente preciso para a quantificação de açúcar redutor em amostras de polpa de fruta.
Éducation inclusif et Mal être dans l'éducation
Authors: Plaisance Eric
Published: April 2021

L’article présente une contribution à la discussion des thèmes de l’inclusion, de la diversité et des inégalités dans les perspectives de recherche et d’intervention dans le cadre scolaire. Il prend l’exemple des défis de l’éducation inclusive. La ligne directrice adoptée est le poids des incertitudes et des risques dans le monde contemporain soumis aux logiques néolibérales, ce qui peut permettre de mieux comprendre et analyser les phénomènes de « malaise » dans l’éducation, la place occupée par le professeur et les nouvelles orientations de l’éducation inclusive qui s’opposent aux phases anciennes de l’éducation spéciale et de l’intégration scolaire. Les considérations finales abordent les paradoxes de la notion d’inclusion et les risques d’exclusion à l’intérieur même de l’école. L’éducation inclusive représente un nouveau défi pour le professeur et nous oriente vers la question de l’éthique comme visée des valeurs humaines fondamentales.
Analysis of the Effect of Financial Ratios on ROA (Return on Asset) at National Private Commercial Banks in Indonesia
Authors: Windri Yenni Permata
Published: April 2021

Abstract Banks are business entities that collect funds from the public in the form of deposits and redistribute them in the form of loans and / or other forms in order to improve the standard of living of many people. Performance is an illustration of the condition of a bank, regarding the good and bad condition of a bank that reflects work performance in a certain period. Financial ratios can help business people, government parties and other users of financial statements in assessing the financial condition and performance of the bank. This study aims to see the effect of financial ratios, namely Loan to Deposit Ratio (LDR), Non Performing Loans (NPL) and BOPO to the performance of National Private Commercial Banks, namely Return on Assets (ROA). The sampling method uses purposive sampling, which uses samples with certain criteria, the samples used in this study are three national private commercial banks namely Bukopin Bank, Mega Bank and OCBC NISP Bank. The data analysis method used is multiple linear regression analysis. Partial test results show that the LDR partially has a non-significant positive effect on ROA in National Private Commercial Banks for the period 2010 to 2013. NPLs partially have a non-significant negative effect on ROA at National Private Commercial Banks for the period from 2010 to 2013 and BOPO partially had a significant negative effect on ROA in National Private Commercial Banks for the period 2010 to 2013.

 

Keywords: Loan to Deposit Ratio, Non Performing Loan, Operational Costs to Operating Income
Nuclear factor erythroid 2-related factor 2 modulates HER4 receptor in ovarian cancer cells to influence their sensitivity to tyrosine kinase inhibitors
Authors: Kankia Ibrahim H. , Paramasivan Poornima , Elcombe Matthew , Langdon Simon P. , Deeni Yusuf Y.
Published: April 2021

Aim:Nuclear factor erythroid 2-related factor 2 (NRF2) is a key component in the cell’s response to oxidative and electrophilic stress and is a transcription factor regulating the expression of a collection of anti-oxidative and cytoprotective genes. Human epidermal growth factor receptor 4 (HER4/erbB4) regulates growth and differentiation in many cancer types. Here, NRF2 and HER4 receptor interactions were investigated in a panel of ovarian cancer cell lines.
Methods:Pharmacological [tert-butylhydroquinone (tBHQ) and retinoid/rexinoid, bexarotene] and genetic [small interfering RNA (siRNA)] manipulations were used to activate or inhibit NRF2 function in the cell line panel (PE01, OVCAR3, SKOV3). Activity of the HER-targeted tyrosine kinase inhibitors, erlotinib (ERL) and lapatinib (LAP), was evaluated after NRF2 activation.
Results:While tBHQ increased the levels of both phosphorylated-NRF2 (pNRF2) and HER4 in PE01, OVCAR3 and SKOV3 cells, bexatorene and NRF2-target siRNA treatment decreased pNRF2 and total HER4 levels. The tBHQ-dependent pharmacological activation of NRF2 attenuated the therapeutic effectiveness of ERL and LAP. Analyses of gene expression data from a HER4 driven reporter system and in vitro or in vivo cancer models, support NRF2 regulation of HER4 expression.
Conclusions:These results support the presence of signaling interaction between the NRF2 and HER4 receptor pathways and suggest that intervention modulating this cross-talk could have anticancer therapeutic value.
BLOOD PRESSURE, HYPOCHONDRIA AND DEPRESSION: MATHEMATICAL MODELS OF RELATIONSHIP
Authors: Pavlovska M. O.
Published: April 2021

Modern clinical diagnostics has standards and medical systems for the diagnosis of hypertension, advanced information technology. Mathematical models of the relationship between systolic blood pressure and psychological indices of hypochondria and depression have been described. Methods of mathematical statistics were applied as follows: factor, cluster, discriminant, regression analyzes, Markov chains, polynomial splines and neural networks, they were implemented in software products, such as NeuroModelDBPM, "Monitoring", VerMed. The presented model of interaction of systolic arterial pressure, Hs−hypochondria, D−depression confirms an importance of these states at an initial stage of arterial hypertension and allows the allocation of four options of psychosomatic relations in patients: organ and system somatic defeats of psychosomatic character, somaticized psychiatric reactions, reactions of exogenous type. It has been shown that disharmonious personality traits, risk factors, disorder of chronobiological structure of blood pressure, left ventricular hypertrophy and its diastolic dysfunction contribute to the formation of nosogeny in hypertension. Their development is hindered by harmonious personality traits, keeping a healthy lifestyle, minimal changes in the chronobiological structure of blood pressure, a slight degree of left ventricular hypertrophy and its diastolic dysfunction. The leading cardiovascular risk factors in patients with hypertension are stress, burdened heredity, low physical activity, carbohydrate abuse, higher education and high socioeconomic status. Nosogeny in hypertension should also be considered as a risk factor, as well as should be taken into account in the stratification of the overall cardiovascular risk and accomplishing a proper adjustments.

Key words: arterial hypertension, mathematical statistics, arterial pressure, hypochondria, depression, information technology.
PATHOGENETIC ROLE OF MYOCARDIAL FIBROSIS: FOCUS ON EXTRACELLULAR MATRIX
Authors: Ambrosova T. M. , Ashcheulova T. V.
Published: April 2021

The main cardiovascular diseases affect the processes of myocardial remodeling, which further contributes to the formation of systolic or diastolic heart dysfunction. The formation of myocardial dysfunction is primarily associated with left ventricular hypertrophy when under hemodynamic loading, firstly, wall rigidity increases, secondly, myocardial fibrosis is formed. The latter is one of the key factors of the hypertrophic process caused by the accumulation of collagen, which leads to a aggravation of the left ventricle relaxation processes. Cardiac remodeling is defined as a group of molecular, cellular, and interstitial changes that are clinically manifested by alterations in the size, shape, and function of heart as a result of the heart muscle injury. It has been determined that fibrosis is an early morphological sign of injury in patients with left ventricular overload, as well as a factor in the development of diastolic and systolic dysfunctions. Compensatory left ventricular hypertrophy transforms into heart failure due to the fibrosis development. In hypertrophy the content of elastic collagen type III decreases and rigid collagen type I increases. The essential role of the extracellular matrix in myocardial fibrosis formation is emphasized. Cardiac fibrosis is a process of pathological remodeling of the extracellular matrix, which leads to abnormalities in its composition and dysfunction of the heart muscle. The extracellular matrix plays a key role in organogenesis and post−traumatic healing in tissue injuries. The study of intercellular interactions of the extracellular matrix will provide a better understanding of the mechanisms of changes in geometry and function of the heart, and investigation of the activity of matrix components will open new opportunities for targeted therapeutic effects on molecular mechanisms of cardiac remodeling.

Key words: diastolic dysfunction, extracellular matrix, myocardial fibrosis, cardiomyocytes, fibroblasts.
Perjanjian Internasional Sebagai Instrumen Rekayasa Global Dan Harmonisasi Prinsip-Prinsip Hukum Lingkungan
Authors: Simbolon Manuel
Published: April 2021

Perjanjian internasional merupakan salah satu sumber hukum internasional yang sering digunakan. Dalam bidang lingkungan hidup, terdapat banyak perjanjian internasional yang telah dibuat untuk mengkoordinasikan kebijakan negara-negara di bidang lingkungan hidup. Perjanjian internasional tersebut digunakan sebagai instrumen rekayasa global. Namun banyak di antara perjanjian internasional tersebut berkarakter soft law sehingga tidak dapat mengikat negara-negara dan mempengaruhi kebijakan nasionalnya di bidang lingkungan hidup.
COVID-19 infekcijos sukelta ilgalaikė hipoksija dėl plaučių pažaidos
Authors: Leleika Arnoldas , Povilonis Paulius , Mašanauskienė Edita
Published: April 2021

Ilgiau nei metus besitęsianti globali COVID-19 pandemija sukėlė vieną didžiausių pasaulio sveikatos krizių istorijoje. Nuo pat pradžių pandemijos priekinėse linijose esantys medicinos darbuotojai bandė įvairius gydymo metodus, kad padėtų pasveikti nuo klastingo viruso ir jo sukeltų padarinių organizmui. Šiuo metu išsiaiškintas tikslus šio viruso patekimo kelias į organizmą, veikimo mechanizmas, ligos eiga bei galimos pasekmės ir baigtys. Šiame straipsnyje analizuojamas 71 metų pacientės, kuriai buvo nustatytas COVID-19 infekcijos sukeltas plaučių uždegimas, pasireiškė tromboembolinė plaučių arterijų komplikacija ir išliko ilgalaikė hipoksija, atvejis. Šio atvejo aprašyme aptariamas COVID-19 viruso sukeltos pneumonijos išsivystymo mechanizmas, klinikinė ligos eiga, pneumonijos diagnostika bei gydymas, ilgalaikės oksigenoterapijos pasekmės bei viruso indukuotos hiperkoaguliacijos padidėjęs krešulių formavimasis.
Miego kokybės ryšys su gyvensenos įpročiais
Authors: Montvidas Vilius , Viliušytė Beatričė
Published: April 2021

Šiuolaikiniame gyvenime kokybiškas miegas tampa dideliu kasdieniu iššūkiu dėl nuolat tobulėjančių technologijų, kurios sudaro galimybes ir vilioja trumpinti miego trukmę, šį laiką išmainant į darbą, socializaciją arba buvimą su šeima. Tyrimai rodo, jog miego kokybei turi įtakos ir gyvensenos veiksniai: mityba, fizinis aktyvumas, el. priemonių, alkoholio ir rūkymo vartojimas įvairiose amžiaus grupėse. Įtraukiant gyvensenos medicinos intervencijas, nukreiptas į gyvenimo būdo keitimą, rastas teigiamas poveikis miego kokybei.
Highly selective difluoromethylations of β-keto amides with TMSCF2Br under mild conditions
Authors: Wang Yakun , Wang Shuaifei , Zhang Conghui , Zhao Ting , Hu Yanqin , Zhang Mingwei , Chen Pengli , Fu Yang , Lv Jieli
Published: April 2021

Without employing any transition metal and other additives, efficient methods for selective difluoromethylations of β-keto amides with TMSCF2Br reagent have been developed under alkaline and open-air conditions. This protocol allows a convenient access to various α-difluoromethyl β-keto amides with excellent yields (up to 93%) and high C/O regioselectivities (up to 99:1). The C/O selectivity of β-keto amides could be easily reversed and controlled by simply changing the base. This protocol can be easily scaled up and the C-difluoromethylation product could be reduced into amino-alcohol derivatives. Moreover, the first enantioselective electrophilic difluoromethylation of β-keto amides has been achieved by phase-transfer catalysis.
Psychological Profile of Patients with Chronic Low Back Pain
Authors: Satar Abdul , Ali Shaista , Anjum Zahin , Kabir Samir Khan , Waqar Muhammad , Arif Muhammad
Published: April 2021

OBJECTIVES:

To assess the frequency of depression, anxiety, and stress in patients with Chronic Low Back Pain (CLBP) using Depression Anxiety Stress Scale (DASS-42).

METHODOLOGY:

This descriptive study was performed from January 2019 to June 2019. All those patients with chronic low back pain with duration of more than 6 months were included. Patients below 20 and above 60 years were excluded to eliminate the effect of extreme ages. The Depression Anxiety Stress Scale (DASS-42) was used in this study.

RESULTS:

In this study, a total of 127 patients were successfully interviewed. The mean age of the sample was 36.46 (SD±7.38) with a minimum age of 22 years and maximum of 59 years. Out of these 127 patients, 83 (65.4%) were female while 44 (34.6%) were male patients. The minimum duration of chronic low back pain in our patients was 8 months while the maximum was 55 months with a mean of 28 months (SD 9.9). The mean DASS score for depression was 11.8 (SD±4.23), anxiety was 7.5 (SD±2.9), stress was 12.1 (SD±4.0). Similarly, both genders had equal level of depression and anxiety but females were more experiencing the stress.

CONCLUSION:

Abnormal levels of stress anxiety and depression are a common finding in our population with CLBP
Factors Influencing the Participation and Engagement of Dental Students in E-Learning During Covid-19 Pandemic
Authors: Butt Hira , Khan Nauman Rauf , Iqbal Ameer Iqbal , Pakistan Khadija Ahmad , Iqbal Shahid , Tahir Fiza
Published: April 2021

OBJECTIVES: To assess the factors that influences the participation and engagement of dental students in online classes. METHODOLOGY: A descriptive cross-sectional study was conducted using a pre-validated questionnaire with 45 barriers items used. The Cronbach Alpha value after removing certain items in our study was calculated to be 0.934, which resulted in 35 barrier items. Recorded data were coded and entered using SPSS version 23.0. Nominal data were presented as frequency and percentage, whereas all numerical data was entered as mean and standard deviation. Factor analysis on questions pertaining to barriers to e-learning was done. RESULTS: The underlying construct of the data was identified using principal component factor analysis. The type of rotation used was Varimax. The value of Kaiser-Meyer-Olkin measure for sampling adequacy (MSA) was 0.880. The criteria used for identifying factors were the latent root criteria. A total of six factors were identified. The overall variance explained by these factors was 61.9%. The barriers ranked the highest were those pertaining to motivational problems and time interruptions (2.8667±0.88524). The barriers that were ranked the lowest were those pertaining to instructors and personal problems (2.3894±0.81059). CONCLUSION: The biggest barrier was found to be motivational problems in attending online classes. The second-highest ranked barrier was social problems. The third barrier included a lack of support services. Technical barriers were ranked fourth. The barrier that was ranked fifth was a lack of pre-requisite skills. The barriers that were reported to be the least were problems pertaining to the instructor and personal problems. KEYWORDS: Motivational Barrier, Social Barrier, Technical Barrier, Instructor and Personal Barrier, Pre-requisite Skill, Kaiser-Meyer-Olkin (KMO
KEBIJAKAN HUKUM PIDANA DALAM PEMBERANTASAN TINDAK PIDANA PENCUCIAN UANG DI INDONESIA
Authors: Riyanda Elsera
Published: April 2021

Tindak pidana pencucian uang disebut sebagai kejahatan yang bersifat ganda dan lanjutan (Follow Up Crime), karena tindak pidana pencucian uang merupakan suatu perbuatan yang diteruskan atau lanjutan dari tindak pidana asal (predicate crime) dimana si pelaku  memproses sejumlah besar uang ilegal hasil tindak pidana menjadi dana yang kelihatannya bersih atau sah menurut hukum, dengan menggunakan metode yang canggih, kreatif dan kompleks. Tujuan penulisan Tesisi ini, yakni; Pertama, Kebijakan Hukum Pidana Yang Ada Sekarang Ini dapat Menanggulangi Tindak Pidana Pencucian Uang di Indonesia , Kedua, Kendala yang dihadapi dalam Kebijakan Hukum Pidana dalam menanggulangi Tindak Pidana Pencucian Uang di Indonesia. Jenis penelitian ini dapat digolongkan dalam jenis penelitian Hukum Normatif, Pengumpulan data dalam penelitian ini menggunakan metode kajian kepustakaan (library research) atau studi dokumenter yaitu dengan menggunakan studi dokumenter atau bahan-bahan pustaka baik dari media cetak, elektronik serta buku-buku yang berkaitan dengan penelitian hukum ini, sumber data yang digunakan, data primer, data sekunder dan data tertier, teknik pengumpulan data dalam penelitian ini dengan studi kepustakaan.
PERLINDUNGAN HUKUM KOPI LIBERIKA RANGSANG MERANTI SEBAGAI INDIKASI GEOGRAFIS DI KABUPATEN KEPULAUAN MERANTI
Authors: Ibnu Rizal
Published: April 2021

Penelitian bertujuan untuk mengetahui  bentuk perlindungan hukum pada saat ini terhadap  tanaman  kopi liberika rangsang yang dihasilkan oleh Kabupaten Kepulauan Meranti Riau  dan mengetahui bentuk gagasan atau konsep ideal yang dicita-citakan bagi perlindungan Indikasi geografis kopi liberika rangsang Meranti. Penelitian karya tulis ini merupakan penelitian normatif empiris yang dalam penelitiannya mengkaji dari implementasi peraturan yang ada terhadap ketentuan hukum serta melihat secara faktual terhadap fakta yang terjadi dalam masyarakat dalam rangka mencapai tujuan yang dimaksud, penerapan dari hasil penelitian ini menciptakan pemahaman pelaksanaan dari ketentuan apakah sudah berjalan secara patut atau tidak, sedangkan jika dilihat dari sifatnya penulisan penelitian ini bersifat deskriptif analitis karena memberikan gambaran tentang keadaan yang terjadi secara lengkap dan jelas secara sistematis dan mengkajinya  tentang perlindungan hukum terhadap kopi liberika rangsang meranti di Kabupaten Kepulauan Meranti Riau dengan lokasi penelitian dilakukan di ibukota dari Kabupaten Kepulauan Meranti yakni di kota Selatpanjang, karena komunitas petani yang mengajukan Indikasi geografis berkedudukan di Kota Selatpanjang, dan juga karena kedudukan pemerintahan Kabupaten Kepulauan Meranti berada di Kota Selatpanjang.
EKSISTENSI PLURALITAS DALAM PIAGAM MADINAH
Authors: Raihana
Published: April 2021

Eksistensi pluralitas dalam Piagam Madinah menggambarkan kemajemukan kota Madinah, baik topografis maupun sosial, budaya, dan agama yang ditandai dengan adanya hubungan ummat Islam dan non Islam (Yahudi dan Musyrikin) melalui suatu perjanjian secara timbal balik terhadap pengakuan agama masing-masing. Hal ini menunjukkan sosok  Nabi Muhammad SAW sebagai seorang siasiy (diplomat) besar, bijaksana dalam mendirikan perikatan umat (republik/ jumhuriyah) yang syarat dengan nilai-nilai Islam. Nilai-nilai Islam tersebut diberlakuannya secara inklusif, diantaranya yaitu ; nilai persamaan umat dan persatuan, kebebasan, toleransi agama, tolong, menolong, dan membela yang teraniaya, musyawarah, keadilan, persamaan hak dan kewajiban, hidup bertetangga, pertahanan dan perdamaian, amar makruf dan nahi munkar, ketakwaan, dan kepemimpinan.