bluuebunny/crossref_metadata_2025 huggingface dataset:
The Mystical Strategies of St. Teresa of Avila
Authors: Tyler Peter
Published: June 2019

"NO ABSTRACT"
ВИДЕОУРОК КАК ПРОИЗВОДНАЯ КЛАССИЧЕСКОГО УРОКА
Authors: Trondina S. O.
Published: June 2019

В данной статье рассмотрены средства обучения, в частности аудиовизуальные. К аудиовизуальным средствам обучения относится видеоурок – современная форма урока. В статье рассмотрены преимущества и недостатки видеоролика.
Malestar emocional, ansiedad y depresión en pacientes oncológicos colombianos y su relación con la competencia percibida
Authors: Moreno Acosta Ana Isabel , Krikorian Alicia , Palacio González Carolina
Published: June 2019

Objetivos: Determinar los índices de malestar emocional, ansiedad y depresión y examinar su relación con la competencia percibida (CP) en pacientes con cáncer. Método: Se recogieron datos sociodemográficos y clínicos de 42 pacientes que consultaron un servicio de psicología de una institución oncológica. Se empleó la Escala de Ansiedad y Depresión Hospitalaria (HADS) y la Escala de Competencia Percibida (ECP). Se obtuvieron estadísticos descriptivos, comparativos y correlacionales. Resultados: Edad promedio 49 ± 10.6 años (rango 22-69), 83% de sexo femenino, diagnóstico más frecuente: cáncer de mama (26.2%). El 61.9% se encontraba en estadio IV, y más del 50%, en tratamiento paliativo. Las puntuaciones en malestar emocional, ansiedad y depresión fueron bajas-medias, y las de CP fueron moderadas. Se observó una relación inversa y significativa entre el malestar emocional y la CP (p < .01). Sin embargo, la correlación entre ansiedad o depresión y CP no fue significativa. Conclusiones: Las creencias de control generales mantienen una relación estrecha con el estado emocional. El investigar sobre la CP tiene ventajas importantes, ya que las creencias generales de control pueden favorecer la adaptación en el proceso de enfermedad.
El significado de la vida y de la muerte para mujeres con cáncer de mama
Authors: Palacios Espinosa Ximena , Lizarazo Ana Milena , Moreno Olivares Karen Stephanie , Ospino Cuello Julio David
Published: June 2019

Tener cáncer promueve reflexiones y cambios en el significado de la vida y de la muerte. Objetivo: Esta investigación cualitativa tuvo como objetivo comprender el significado de la vida y la muerte en un grupo de once mujeres con cáncer de mama. Método: Se realizó una entrevista a cada participante y se clasificó y codificó la información buscando categorías emergentes con base en el enfoque procesual de las representaciones sociales. Resultados: Algunas de las categorías fueron: apoyo, tratamiento, muerte; efectos secundarios; afrontamiento y suicidio; experiencia positiva con el médico y el hospital; reacciones emocionales; conocimiento previo de la quimioterapia; experiencias previas con el cáncer; proceso de diagnóstico y médico como poseedor de conocimiento. Conclusiones: Este estudio permitió aproximarse a la comprensión tanto del cáncer de mama como de los cambios que este genera en el significado de la vida y de la muerte. Así mismo, permitió comprender la importancia de la familia y de la red de apoyo en esta experiencia y el sentimiento de lucha y fortalecimiento del rol social de mujer para afrontar la enfermedad.
El cáncer de colon y recto en cuidados paliativos: una mirada desde los significados del paciente
Authors: Reyes Piñeros Clara Elisa , Saldarriaga cuartas Margarita , Davalos Diana Maria
Published: June 2019

La presente investigación tuvo como objetivo comprender el significado y la manera personal como tres pacientes que recibían atención en cuidados paliativos afrontaron el cáncer de colon y recto y su proceso de enfermedad, cuando esta se encontraba en un estado avanzado e incurable. La metodología fue cualitativa con aproximación fenomenológica. Mediante entrevistas en profundidad se exploraron las creencias y se obtuvo información de los pacientes acerca del origen de la enfermedad, las expresiones emocionales y los recursos y obstáculos para afrontarla. Los resultados permitieron comprender que el significado construido alrededor del diagnóstico está relacionado con sus experiencias previas, la información que tenían acerca de su condición y la presencia o no de síntomas. Se destaca el hecho de que no percibieron la enfermedad como amenaza, que se sintieron tranquilos frente al diagnóstico y de que no tenían conciencia de la proximidad de la muerte. Las expresiones emocionales variaron desde la tristeza, la sorpresa y la angustia al momento del diagnóstico, hasta la aceptación, la confianza en Dios y en los tratamientos médicos como vía para la curación. El seguimiento de las recomendaciones médicas y la confianza en Dios se convirtieron en las principales estrategias para afrontar la enfermedad.
Factores asociados a la experiencia de sufrimiento en pacientes con cáncer avanzado
Authors: Krikorian Alicia , Limonero Joaquín T.
Published: June 2019

Objetivo: Examinar la experiencia de sufrimiento y su relación con problemas físicos, psicológicos, sociales y espirituales en pacientes oncológicos. Método: 98 enfermos de una institución oncológica en cuidados paliativos participaron en el estudio. Se examinó el grado de sufrimiento, la intensidad y amenaza de síntomas y problemas físicos, psicológicos, sociales y espirituales, el grado de ajuste y de conciencia de enfermedad y las estrategias de afrontamiento. Se realizaron análisis estadísticos descriptivos y comparativos. Resultados: Aproximadamente el 50% de los participantes manifestaron un sufrimiento moderado. Los problemas más frecuentes fueron malestar general, astenia, alteración del estado de ánimo, pérdida de la autonomía, tristeza, preocupación por el futuro de la familia y sufrimiento. Un sufrimiento moderado a severo se asoció con mayor dificultad en el ajuste general y uso de la estrategia de afrontamiento de pensamiento desiderativo. Un menor sufrimiento se asoció con estrategias de reestructuración cognitiva y evitación de problemas. Conclusiones: Se resalta la importancia de atender los aspectos subjetivos de la experiencia. Cualquier síntoma o problema tiene el potencial de generar sufrimiento, en la medida en que sea percibido como amenazante, y los procesos regulatorios con los que cuente la persona impidan la adaptación.
Decision-making efficiency, accountability and democracy in inter-municipal cooperation arrangements: The case of Iceland
Authors: Eyþórsson Grétar Þór
Published: June 2019

Inter-municipal cooperation in Iceland has a history of many decades. There has been significant cooperation between smaller and larger municipalities in order to improve the provision of services, which in many cases has been difficult for the small and smallest units – a question of capacity. In this article, the main task is to look at the democratic aspect of inter-municipal cooperation arrangements. The main research questions are on consequences for democracy, democratic accountability, efficiency and decision-making in this context, which have been pointed out as the main democratic concerns by various European researchers. To answer this for the case of Iceland, responses to questions on the topic from two different surveys among local leaders are analysed. The main conclusion is that the general concerns stated by the above-mentioned researchers also seem to be present in the case of inter-municipal cooperation in Iceland.
Do municipal amalgamations affect interregional migration?
Authors: Karlsson Vífill , Eyþórsson Grétar Þór
Published: June 2019

This paper examines the change of interregional migration following municipal amalgamations. Interregional migrations are mostly triggered by differentials in household utilities, local economic conditions, amenities and the like. Thus, it is reasonable to believe that if an amalgamation of municipalities leads to a better service or lower local taxes in a community, it would attract new inhabitants and thus, increase the net-migration - as suggested by Tiebout (1956). A macro panel data set from Iceland was used that represents several essential variables of the housing market for 79 municipalities in Iceland during the period from 1993 to 2006. The results returned mixed effects on net migration. The amalgamations seem to have had both negative and positive effects on net-migration due to the differences in the number of municipalities in each merger and the similarities in the population sizes of the previous municipalities that joined each merger.
Kynferðisleg áreitni á vinnustað: Aðgerðir, aðgerðaleysi og leiðin fram á við
Authors: Pétursdóttir Gyða Margrét , Hjálmarsdóttir Kristín Anna
Published: June 2019

Í kjölfar íslensku #Metoo-hreyfingarinnar hefur verið kallað eftir úrbótum og leiðum til að útrýma kynferðislegri áreitni, einni birtingarmynd kynbundinnar mismununar. Sátt virðist ríkja um að skýr stefna, verklagsreglur og fræðsla séu lykillinn að árangri. Engu að síður sýna rannsóknir að jafnréttisverkefni mæta gjarnan mótstöðu og viðnámi. Hér er fjallað um niðurstöður aðgerðarannsóknar sem framkvæmd var hjá embætti Lögreglunnar á höfuðborgarsvæðinu og sjónum beint að formlegu og óformlegu viðnámi til að greina hindranir og tækifæri í jafnréttisstarfi sem ætlað er að stemma stigu við kynferðislegri áreitni. Markmið rannsóknarinnar var tvíþætt; í fyrsta lagi kortlagning á stöðu mála og í öðru lagi fræðsla meðal starfsfólks. Í greininni er sérstök áhersla lögð á viðbrögð við og reynslu af svokölluðum umræðuvettvangi sem ætlað er að fræða og vekja til vitundar og tilheyrði seinni hluta rannsóknar. Viðnám birtist með ýmsum hætti í rannsókninni. Tilhneiging var til þess að varpa ábyrgðinni annað, bjargir voru takmarkaðar þegar á reyndi og tilhneiging var til þess að einblína á þátt einstakra einstaklinga í stað þess að sjá kynferðislega áreitni sem hluta af vinnumenningu. Á umræðuvettvangi gafst tækifæri til að rýna í þessar birtingarmyndir viðnáms, fræða og vekja til vitundar um ólíkar birtingarmyndir kynferðislegrar áreitni. Niðurstöðurnar geta nýst öðrum fyrirtækjum og stofnunum til að skipuleggja og innleiða slík jafnréttisverkefni með markvissari hætti.
Desvelando opresiones y resistencias de las mujeres en Zumarraga (País Vasco): un análisis interseccional para profundizar la democracia participativa en términos de justicia social
Authors: Ahedo Gurrutxaga Igor , Ureta García Miriam
Published: June 2019

La presente investigación persigue alcanzar tres objetivos: (i) desvelar cómo diferentes mujeres están atravesadas por entrecruzados ejes de opresión de género, clase, raza, edad y/o movilidad en un contexto de desmantelamiento industrial y de expulsiones en el mercado de trabajo asalariado en Zumarraga (País Vasco); (ii) visibilizar sus formas de resistencia y (iii) un tercer objetivo de carácter más normativo que busca desactivar situaciones de vulnerabilidad. Para ello, el estudio hará uso de las potencialidades heurísticas que ofrecen los marcos propuestos por Patricia Hill Collins la «matriz de dominación», los «ámbitos de poder» y las «políticas de comunidad» planteados de forma articulada como herramienta de análisis interseccional aplicado. Bajo este enfoque, se han puesto en diálogo las experiencias vivenciales de 37 vecinas y vecinos de Zumarraga y los resultados de dos talleres participativos con mujeres, orientados a activar sus demandas en aras de profundizar la democracia participativa en términos de justicia social.
Población y poblamiento en los Parques Nacionales andaluces. El valor del entorno residencial como detonante de los procesos de naturbanización
Authors: Del Valle Ramos Carolina , Prados Velasco Maria José
Published: June 2019

Los procesos de naturbanización explican cómo la presencia de un espacio protegido estimula los procesos de urbanización en su área de influencia. Este artículo investiga las percepciones y motivaciones de los residentes permanentes y temporales a partir de metodologías cualitativas. El principal objetivo es explorar las relaciones entre atracción residencial y preservación de los valores ambientales en el marco de los procesos de naturbanización. La investigación analiza de manera comparada los resultados de una encuesta a los residentes en los municipios que rodean los Parques Nacionales de Doñana y Sierra Nevada. Los resultados revelan diferencias en el valor que se reconoce al entorno residencial; la calidad ambiental y la belleza del paisaje como apoyo al desarrollo residencial en los Parques Nacionales. Unas diferencias que muestran correspondencia con el nivel formativo y económico de la población encuestada y con su historia residencial.
Reseña de Azares y decisiones. Recuerdos personales
Authors: Pillet Capdepón Félix
Published: June 2019

Veinte años después de la publicación de An Autobiography of Emotion, Mind, and Spirit (1999) del geógrafo humanista-fenomenológico Yi-Fu Tuan, ahora nos sorprende Horacio Capel con Azares y decisiones. Recuerdos personales (2019). Mientras el primero hizo geografía para conocer el significado de su existencia “quiero saber qué es lo que hacemos aquí, qué queremos de la vida”, el segundo, se debió “a una acumulación de azares y oportunidades profesionales especialmente favorables”. Capel pronto descubriría que la visión del geógrafo es muy específica y característica: “permite ver aspectos que otros no perciben”.
Jorge Amado na juventude (1932-1936): O Boletim de Ariel como espaço de reflexão intelectual
Authors: Matheus de Mesquita e Pontes
Published: June 2019

Entre 1932 e 1933 o jovem escritor Jorge Amado realizava uma migração editorial: saía da Schmidt Editora, que publicou seu primeiro livro autoral, e adentrava na Ariel Editora, que lançou seus primeiros “romances proletários” que abordavam temas classistas, regionais e raciais. A mudança também significava novas mediações com novos grupos sociais e o distanciamento em relação aos intelectuais católicos que predominavam na Schmidt. O fato da Editora Ariel manter um periódico mensal, o Boletim de Ariel, contribuiu para que o literato expressasse seus novos interesses temáticos presentes nos romances Cacau (1933), Suor (1934), Jubiabá (1935), Mar morto (1936) e Capitães da areia (1937), além de participar dos debates impulsionados pelos seus novos agrupamentos, através da escrita de artigos e ensaios no periódico.
Africanidades, corporeidade e opacidade nos primórdios da história da imprensa ilustrada
Authors: Túlio Henrique Pereira
Published: June 2019

Este artigo se propõe a analisar parte específica da produção da imprensa ilustrada na Bahia, especialmente do jornal A Coisa (1897-1904), o caráter de seus textos com temáticas africana e afro-brasileira, pensando a autoria organizada por grupos de redatores amigos com propósitos ideológicos consonantes à segmentação impulsionada por países como a França e os Estados Unidos. Ao perceber a efetiva atuação de Arthur Arezio da Fonseca, redator e caricaturista negro, assim como a presença de nomes e estereotipia produzidos por e sobre africanos e seus descendentes, interessei-me por analisar como a temática das africanidades e da corporeidade étnica se deu de forma comprometida e distanciada, de modo a contribuir para a opacidade ou visibilidade de determinados padrões na imprensa ilustrada produzida na Bahia.
O desenvolvimento de motivos formadores de sentido no contexto das atividades de ensino e estudo na escola pública brasileira
Authors: Franco Patrícia Lopes Jorge
Published: June 2019

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Diabetic polyneuropathy: a current algorithm for patient management
Authors: Akhmedzhanova L. T. , Barinov A. N. , Solokha O. A. , Strokov I. A. , Doronina O. B. , Doronina K. S. , Rozhdestvensky A. S.
Published: June 2019

Diabetic polyneuropathy (DPN) is the most common chronic complication of diabetes mellitus and can develop just at the prediabetes stage. As DPN progresses and, in the absence of its adequate treatment, leads to worse quality of life and its shorter expectancy in patients. The paper discusses current clinical guidelines for the examination and management of patients with DPN, diagnostic methods, and pathogenetic treatment of this disease.
Vascular factors in the genesis of dementia and the optimization of patient management
Authors: Ostroumova O. D. , Kochetkov A. I.
Published: June 2019

The review considers the problem of cognitive impairment (CI) and dementia in patients from older age groups, as well as the safety of antidementia agents with a focus on adverse cardiovascular drug reactions. Special attention is paid to the role of cardiovascular risk factors in the genesis of CI and all types of dementia. It is emphasized that the treatment of patients with CI is primarily aimed at monitoring vascular risk factors, preventing stroke and progression of chronic cerebrovascular disease, and, therefore, improving cognitive functions. Postoperative cognitive dysfunction in elderly patients, in particular during coronary artery bypass surgery, is highlighted. Non-drug and drug measures to prevent the progression of CI and dementia are described in detail. The significant importance of multimorbidity and polypragmasia in elderly patients with dementia is noted; data on the cardiovascular safety of anti-dementia drugs are presented.
Patent foramen ovale and embolic cryptogenic stroke
Authors: Kulesh A. A. , Shestakov V. V.
Published: June 2019

The paper considers the actual problem of cryptogenic stroke and patent foramen ovale (PFO). It highlights the issues of pathogenesis and role of paradoxical embolism in the development of cerebral circulation disorders. The features of clinical manifestations and neuroimaging pattern of stroke in the presence of PFO are described. Ultrasound diagnostic techniques used to verify a cardiac anomaly are characterized. Approaches to establishing a cause-and-effect relationship between the presence of PFO and the development of stroke are presented. The current possibilities of secondary prevention in this category of patients, in particular the results of studies of percutaneous PFO occlusion, are discussed.
Differential chemoreactome analysis of synergistic combinations of tolperisone and nonsteroidal anti-inflammatory drugs
Authors: Torshin I. Yu. , Gromova O. A. , Stakhovskaya L. V. , Semenov V. A. , Gromov A. N.
Published: June 2019

The concurrent use of muscle relaxants and nonsteroidal anti-inflammatory drugs (NSAIDs) is a promising treatment for painful muscle hypertonia and convulsive states.

Objective: to identify the most effective and safe synergist combinations of tolperisone and NSAIDs.

Material and methods. A differential chemoreactome analysis was employed to evaluate the effects of the muscle relaxant tolperisone and five NSAIDs (dexketoprofen, etoricoxib, meloxicam, naproxen, and diclofenac). The biological activities of the molecules under study were assessed in five sections: 1) inhibition of the proteins of prostaglandin and leukotriene metabolism; 2) inhibition of the effects of the transcription factor nuclear factor kappa, tumor necrosis factor-, and other anti-inflammatory mechanisms; 3) inhibition of excessive blood coagulation and platelet aggregation; 4) vasodynamic effects; 5) antitumor properties on cell lines in culture.

Results and discussion. Based on the differences in the pharmacological activity profiles of tolperisone and NSAIDs under study, the investigators identified the most promising synergistic combinations, in which both active ingredients complemented each other as effectively and safely as possible. The obtained estimates of the degree of synergism of various combinations of tolperisone and NSAIDs hold that the most promising antithrombotic, and antitumor effects.

Conclusion. The results of this study will help adequately choose combinations of muscle relaxants and NSAIDs in patients with muscle hypertonia, which will be able to improve the efficiency and safety of treatment.
Schizophrenia-like disorder in Wilson's disease
Authors: Spirina I. D. , Fawzy E. S. , Shevchenko Yu. N. , Shornikov A. V. , Smolianova A. V. , Nikolaychik A. N.
Published: June 2019

Wilson's (Wilson–Konovalov) disease (WD) is a chronic progressive disease resulting from impaired body copper metabolism with damages to target organs (liver, brain, and kidneys). The paper describes a clinical case of organic delusional (schizophrenia-like) disorder in a patient with WD. The characteristic feature of its psychiatric onset in the patient is schizophrenia-like disorders in the absence of neurological and gastroenterological symptoms. Because of this onset of WD, patients have not received specific treatment for a long time (frequently before the appearance of the Kayser–Fleischer rings or the occurrence of cirrhosis). Thus, the diagnostic search should include WD in young patients with a primary psychotic episode. The search for early effective methods for WD verification is of interest for further investigations.
“Do we really need this class?”: Former K-12 Teachers Transitioning to Teaching as University Faculty
Authors: Jimenez-Silva Margarita , Kulinna Pamela Hodges , Cirell Anna Montana , Balmaseda Matt
Published: June 2019

Background: It was the purpose of this study to investigate graduate students’ perceptions and the processes related to learning to teach at university/college level using  socio-cultural theory and ecological systems. . Methods: A survey based on Bronfenbrenner’s Ecological Systems (1977)  and a Knowledge –Confidence-Usefulness instrument (Barton-Arwood, Morrow, Lane & Jolivette, 2005) was administered to graduate students four times (N=10). Four interviews, class observations and document analyses were also conducted.  Descriptive statistics were calculated for the survey data and interview data were analyzed via constant comparison. Results: Findings showed high internal consistency reliability of the items (>.93) and that graduate students’ perceptions of their experiences to prepare to teach at the university level were quite positive. Themes were related to being confident, having the potential to be effective at the post-secondary level, and a mismatch between experiences and expectations. Using the emergent process model of Chi and colleagues (2012), overall perceived dynamics (macro level), the individuated university agents/students within the socialization process (micro level) and the social subgroups into which the agent/student network (meso level) support an ecological form of faculty development. Conclusions: Results provide support for an ecological systems model as well as insights into faculty teaching development.
Enhancing the Emotional Intelligence of Students: Helping the Critical Few
Authors: Wolfe Kara
Published: June 2019

Research has shown that students’ emotional intelligence (EI) can be enhanced with time intensive instructional methods other studies are inconclusive. I looked at the impact of including short EI lessons in an introductory hospitality management class. Results show that students who started with low EI increased their scores significantly; however, those with medium and high EI did not. More intensive EI lessons may be needed for those who start with higher levels of EI. Scholarship of Teaching and Learning (SoTL) reflections were used and the results of the current study were also compared to other similar studies to identify EI teaching methods among faculty in other disciplines. My recommendations are included for those who want to incorporate EI lessons into their classes to enhance students’ emotional and social competencies.
“There is no escaping it”: Graduate Student Conceptions of Environment and their Implications for Learning Motivation and Public Health Curricula
Authors: Cheesman Katherine L , Ahonen Emily Q
Published: June 2019

This manuscript stems from observations the authors made while teaching an environmental health course, which is part of a Master of Public Health (MPH) degree. Observations of student attitudes and patterns in course feedback prompted questions about how to pique interest in the course.  Since research on motivation has shown that adult learners build new knowledge from what they believe they already know, we first sought to better understand this basis for learning. On the first day of class, students were administered an assignment prompting them to "define environment" in their own words; data were analyzed for content. Results characterize student conceptions of environment as being (1) beyond human influence and (2) individually-focused. The implications of these "alternative conceptions" of environmental public health for educators seeking to motivate adult learners are discussed. Restructuring coursework to reflect Transformative Learning Theory (TLT) is identified as a potential solution to student amotivation.
Difference as Punishment or Difference as Pleasure
Authors: Barolini Teodolinda
Published: June 2019

Dante’s linguistic treatise, De vulgari eloquentia, is not without joy in linguistic difference and invention. However, the treatise’s signature attitude toward linguistic difference is signaled early in Book 1 by the powerfully punitive account of the Tower of Babel. Linguistic diversity, aka “confusion of tongues”, is the punishment meted out to Nimrod and his followers for their presumptuous building of the Tower of Babel: thus, difference is punishment. This essay traces Dante’s evolution as he moves from De vulgari eloquentia to the encounter with Nembrot (as Dante calls Nimrod) in Inferno 31 to Adam’s great discourse on linguistic creation in Paradiso 26: from difference as punishment to difference as pleasure. Dante’s evolution in the linguistic sphere correlates moreover with another transition: from the treatise’s castigation of Eve as a speaker, presumptuosissima Eva, to the Beatrix loquax of Paradiso.
Error Aligned
Authors: Shoemaker Tyler
Published: June 2019

This essay tracks the digital afterlives of etaoin shrdlu, typographic error turned textual agent. A media effect of Linotypes, this phrase was meant to notify editors that their compositors’ fingers had slipped during transcription and a hot-metal line needed to be pulled. It was an internal memo, passed around the printshop — and it is now a recurring text string in digital archives of newspaper pages, where the phrase’s accidental inclusion in printed matter has been newly reset by automatic transcription processes. After examining the place of Linotypes in a long history of machine reading, I argue that the presence of this machine’s error signal in digital corpora presents an opportunity to consider the extent to which automatic transcription works from an interpretive disposition.
KETIDAKTERATURAN HUKUM PENGAKUAN DAN PERLINDUNGAN MASYARAKAT HUKUM ADAT DI INDONESIA
Authors: Sulaiman Sulaiman , Adli Muhammad , Mansur Teuku Muttaqin
Published: June 2019

Peraturan perundang-undangan terkait pengakuan dan perlindungan masyarakat hukum adat (MHA) sudah banyak dilahirkan tapi masyarakat hukum adat justru merasakan ketidakteraturan hukum. Tulisan ini membahas apa yang menyebabkan ketidakteraturan dalam pengakuan dan perlindungan MHA, bagaimana menjaga orientasi pembaruan hukum terkait MHA, dan tata pikir yang seperti apa perlu dibangun dalam rangka pengakuan dan perlindungan MHA di Indonesia. Penelitian ini menemukan bahwa ketidakteraturan dalam pengakuan dan perlindungan hukum MHA terjadi karena banyak sebab, antara lain ragam istilah dan banyaknya dimensi serta lembaga yang menangani MHA itu sendiri. Orientasi pembaruan hukum terkait MHA terlihat adanya pengajuan yudicial review terhadap UU yang tidak sejalan dengan UUD 1945. Ada empat putusan MK yang sangat penting terkait dengan keberadaan MHA, yakni Putusan MK No. 001-21-22/PUU-I/2003 dan No. 3/PUU-VIII/2010 (memperjelas tolak ukur frasa “sebesar-besar kemakmuran rakyat”), Putusan MK No. 10/PUU-I/2003 (memperjelas empat syarat MHA), Putusan MK No. 35/PUU-X/2012 (membedakan hutan adat dan hutan negara), dan Putusan MK No. 006/PUU-III/2005 dan 11/PUU-V/2007 (dasar kerugian konstitusional).
FUNGSI PENGAWASAN OLEH INSPEKTORAT PENGAWASAN DAERAH BERBASIS PENGADUAN MASYARAKAT DALAM PERSPEKTIF HUKUM PROGRESIF
Authors: Trisusilowaty Dian , Lumbanraja Anggita Doramia , Suteki Suteki
Published: June 2019

Inspektorat Pengawasan Daerah (Itwasda) bertugas melakukan pengawasan internal di lingkungan Kepolisian Daerah dan juga bertugas menerima aduan masyarakat yakni dalam bentuk informasi, keluhan, ketidakpuasan dan atau penyimpangan atas kinerja Kepolisian Daerah guna mendapatkan penyelesaian dan kepastian hukum. Penelitian ini mengkaji perspektif Hukum Progresif mengenai fungsi pengawasan preventif oleh Inspektorat Pengawasan Daerah melalui aduan masyarakat di lingkungan Kepolisian Daerah, menggunakan metode penekatan penelitian socio-legal dengan analisa kualitatif. Faktor pendorong pelaksaanaan pengawasan: adanya koordinasi dan kerjasama yang baik antar satuan fungsi, Struktrual Kepolisian berjenjang yang bersifat mutlak, dan dukungan masyarakat terhadap keberadaan Itwasda. Faktor penghambat pelaksanaan fungsi pengawasan adanya kewenangan Itwasda yang terbatas, penerimaan aduan masyarakat yang tidak satu pintu, tidak seimbangnya jumlah sumber daya pengawas, pengawasan terhadap rekan sejawat dan kurangnya pemahaman masyarakat terhadap mekanisme pengaduan. Konsep fungsi pengawasan yang ditawarkan agar lebih mampu mencegah tindakan indisipliner anggota kepolisian berbasis aduan masyarakat yaitu, perlu adanya mekanisme pengaduan masyarakat satu pintu, penggabungan penyidik dari beberapa satuan fungsi, komputerisasi pengaduan dan perlu ada Hukum Acara Pidana khusus bagi Aparat Penegak Hukum.
THE CONSUMER PROTECTION ISSUES TOWARD THE TRADEMARK CIRCULATION OF THE COUNTERFEIT HEALTH PRODUCTS
Authors: Cakrawibawa Ryan Adhyatma , Roisah Kholis
Published: June 2019

This research purpose is to analyze the consumer legal protection efforts and reviewing obstacle factor of implementation of consumer protection related to the trademark circulation of the counterfeit health products in Central Java. This research carried out is a empirical research.. The collecting data used are library research and field studies. The results of this study indicate that There so many parties that involved to handle this case in regard with The Consumer legal protection related to the trademark circulation of health product including, Drug and Food Inspection Agency, Health Office, Industry and Trade Office, and Central Java Special Criminal Review of the Central Java Regional Police. The counterfeiting trademark and health products will be handled by the Commercial Court and Drug and Food Inspection Agency. The criminal legal protection by giving penalties to people who have committed crimes and trademark violations. The factors inhibiting the implementation of the consumer legal protection related to the trademark circulation of health product in Central Java: the lack of the public awareness toward the counterfeit trademark of health product and the lack of the public awareness to report the existence of counterfeit drugs to the authorities.
Using Multilayer Perceptron Artificial Neural Network for Predicting and Modeling the Chemical Oxygen Demand of the Gamasiab River
Authors: Parsimehr Mohamad , Shayesteh Kamran , Godini Kazem , Bayat Varkeshi Maryam
Published: June 2019

Concerns about water quality have widely increased in the last three decades; thus, water quality is now as important as its quantity. To study and model the quality of the Gamasiab River, its data, including chemical oxygen demand (COD), biological oxygen demand (BOD), dissolved oxygen (DO), total dissolved solids (TDS), total suspended solids in water, acidity, temperature, turbidity, and cations and anions were measured at four stations. Then, the correlations between these parameters and COD were measured using Pearson’s correlation coefficient and modeled by multilayer perceptron artificial neural network. In order to minimize the cost of the experiments performed and to provide the input parameters to the artificial neural network based on the correlations between the data and COD, the number of input parameters was reduced and finally, model No.3, with the Momentum training function and the TanhAxon activation function with the validation correlation coefficient of 0.97, mean absolute error of 2.88, and normalized root mean square error of 0.11 was identified as the most accurate model with the lowest cost. The results of the present study showed that the multilayer perceptron neural network has high ability in modeling the COD of the river, and those data correlated with each other have the greatest effect on the model. Moreover, the number of input parameters can be reduced in order to lower the cost of experiments while the performance of the model is not undermined.
Numerical investigation of hemodynamic performance of a stent in the main branch of a coronary artery bifurcation
Authors: Razavi Seyed Esmail , Farhangmehr Vahid , Babaie Zahra
Published: June 2019

Introduction: The effect of a bare-metal stent on the hemodynamics in the main branch of a coronary artery bifurcation with a particular type of stenosis was numerically investigated by the computational fluid dynamics (CFD). Methods: Three-dimensional idealized geometry of bifurcation was constructed in Catia modelling commercial software package. The Newtonian blood flow was assumed to be incompressible and laminar. CFD was utilized to calculate the shear stress and blood pressure distributions on the wall of main branch. In order to do the numerical simulations, a commercial software package named as COMSOL Multiphysics 5.3 was employed. Two types of stent, namely, one-part stent and two-part stent were applied to prevent the build-up and progression of the atherosclerotic plaques in the main branch. Results: A particular type of stenosis in the main branch was considered in this research. It occurred before and after the side branch. Moreover, it was found that the main branch with an inserted one-part stent had the smallest region with the wall shear stress (WSS) below 0.5 Pa which was the minimum WSS in the main branch without the stenosis. Conclusion: The use of a one-part stent in the main branch of a coronary artery bifurcation for the aforementioned type of stenosis is recommended.
Intra-urban patterns of neighborhood-level social capital: a pilot study
Authors: King Jaron , Hine Cassidy A. , Washburn Tessa , Montgomery Hunter , Chaney Robert A.
Published: June 2019

Background: Social capital is a construct of interaction and social trust in one’s fellow community members. These interactions can provide a safety net for individuals in terms of information, social support, and adherence to social norms. While a number of studies have previously examined the relationship between social capital and health outcomes, few have examined the theparallel relationship of social capital and geographic "place" with respect to health outcomes. Methods: Considering social capital as facilitated by specific structures, we evaluate the relationship between neighborhood-level social capital and disability rates in a major Southern US city. Disability rates were collected through neighborhood-level data via the AmericanCommunity Survey (ACS) and compared to a geocoded map of neighborhood-level social capital measures during spring, 2016. Results: Higher social capital within a neighborhood coincided with lower disability rates in that neighborhood (r=-0.14, P=0.016) when compared to random assortment models. Conclusion: Findings from this research add evidence to the value of the built environment, not only providing resources and shaping choices, but for facilitating important social relationships.
Duration of untreated psychosis of first-episode psychotic disorders in Yogyakarta, Indonesia
Authors: Marchira Carla R. , Supriyanto Irwan
Published: June 2019

Introduction: Duration of untreated psychosis (DUP) is an important predictor for prognosis in first episode of psychotic disorders. Caregivers often seek help from alternative healers first and health professional later. These would delay proper treatments for the patients, resulting in more severe symptoms and lower functioning on their visit to medical facility. The present study aims to find the association between DUP, symptoms severity, and global functioning in patients with first-episode psychotic disorders. Methods: We identified 100 patients with first episode of psychotic disorders and their caregivers. The instruments used were Brief Psychotic Rating Scale (BPRS), Positive and Negative Syndrome Scale (PANSS), Premorbid Schizoid-Schizotypal Traits (PSST), and Global Assessment of Functioning (GAF). Results: There were no significant association between BPRS, PANSS, PSST, and GAF scores and DUP in our subjects. Nevertheless, we found that men had significantly longer DUP compared to women. Conclusion: We found significant association between sex and DUP in this study. Longer DUP leads to delayed treatments and poorer prognosis. Further study is required to confirm our finding.
A case of avascular necrosis of capitate bone in an air compressor jack hammer worker
Authors: Tabrizi Ali , Aidenlou Ali
Published: June 2019

Introduction: Avascular necrosis (AVN) is very rare in capitate bone. It mostly occurs due to direct trauma to wrist. However, it could also occur as the result of disturbed blood supply due to repetitive micro-trauma in rare cases. Case Report: In this report, a 30-year-old man who was an air compressor jack hammer worker with chronic wrist pain was presented. Imaging revealed a low-signal intensity lesion on T1-weighted which supported AVN of capitate. Blood supply damage was due to continuous stress to palmar hand as the consequence of working with air compressor jack hammer which led to AVN of capitate. Conclusion: AVN of capitate could occur as the result of repetitive micro-trauma. It has a high correlation with the job of patients. Radiography does not help in the first stages. Magnetic resonance imaging (MRI) has high diagnostic sensitivity. In the primary stages in patients with occupation-induced AVN, it could be improved by changing the job and temporary immobilization.
Infertile Couples' Needs after Unsuccessful Fertility Treatment: a Qualitative Study
Authors: Ebrahimzadeh Zagami Samira , Latifnejad Roudsari Robab , Janghorban Roksana , Mousavi Bazaz Seyed Mojtaba , Amirian Maliheh , Allan Helen T
Published: June 2019

Introduction: Infertility is a major medical issue. Investigations and treatment of infertility are the beginning of a complex, time-consuming and stressful process for couples that may fail well. The present study explored the needs of infertile couples following treatment failure with Assisted Reproductive Technologies (ARTs). Methods: A descriptive qualitative study was conducted in an Iranian infertility center, in the Northeast of the country between April 2016 and June 2017. The researchers recruited 29 individuals including 9 couples, 9 women and two men with primary infertility through purposive sampling. The data were collected using semi-structured interviews and analyzed iteratively, using conventional content analysis with MAXQDA software. Results: The main concepts obtained from the data were classified into one theme titled: ""The need for support"" and four main categories along with their subcategories, and included the need for psychological support, the need for more useful information, the need for social support and the need to access to supplementary services. Conclusion: The findings show that following treatment failure, the infertile patients’ expressed needs and preferences were not met. Identifying and meeting their needs may help the infertile couples to deal with ARTs failure and to reach a decision about future treatment.
Vascular dysfunction and atherosclerosis in chronic kidney disease; A distinct entity
Authors: Silva Eranga Harshani , Wickramatilake Chandima Madhu , Lekamwasam Sarath , Mudduwa Lakmini Kumari Boralugoda , Ubayasiri Ranjuka Arushana
Published: June 2019

Cardiovascular disease (CVD) is prevalent among patients with chronic kidney disease (CKD) and its occurrence and severity cannot be fully defined by the conventional cardiovascular risk factors namely age, hypertension, dyslipidaemia, diabetes mellitus and obesity. Contemporary studies have examined the role of non-conventional risk factors such as anemia, hyperhomocysteinemia, calcium and phosphate metabolism, vascular stiffness due to endothelial dysfunction ( ED), oxidative injury, and inflammation in the causation of CVD in CKD. Therapeutic interventions used in non-CKD patients are found to be less effective on patients with CKD. The purpose of this review was to gather available evidence on the CVD risk among CKD patients. Numerous mechanisms have been postulated to describe the increased atherogenicity in CKD patients. We discuss these mechanisms especially arterial stiffness, ED and inflammation in detail. In conclusion, CVD in CKD is still an unexplored area which needs further studies to uncover the possible mechanisms. Identifying newer therapies to improve health among this group of patients is of paramount importance.
Selenium effects on antioxidant and inflammatory indices in renal ischemia-reperfusion injury in rats
Authors: Ahmadvand Hassan , Babaeenezhad Esmaeel , Nayeri Hashem , Zarei Nezhad Zahra
Published: June 2019

Introduction: Selenium (Se) is an antioxidant and reactive oxygen species (ROS) scavenger. Objectives: This study was conducted to evaluate the effects of Se on renal functional parameters, oxidative stress biomarkers, myeloperoxidase (MPO) activity, and the nitric oxide (NO) level in renal ischemia-reperfusion (IR) injury in rats. Materials and Methods: Twenty-four male Wistar rats (180–200 g) were selected and subsequently divided into three groups (n=8); group 1 as the control group, group 2 as the untreated group (IR without treatment) and group 3 as the IR group (treated with Se (1 mg/kg/d, intraperitoneally). The period of Se administration was 2 weeks before the inducing renal IR. To cause renal IR, renal pedicles were occluded by safe clamps for 45 minutes. Then, the clamps were removed and 24 hours was considered as reperfusion. After the study, blood sampling from the hearts and the removal of the left kidney was conducted immediately for biochemical measurements. Results: Renal IR significantly increased serum levels of urea, creatinine (Cr), serum and renal malondialdehyde (MDA) levels, serum NO level, and MPO activity. It significantly decreased serum and renal glutathione (GSH) levels, serum paraoxonase 1 activity, serum and renal activities of catalase (CAT), and glutathione peroxidase (GPx). Se could reverse these findings, but the increase of paraoxonase 1 activity and the decrease of MPO activity in IR animals were not significant. Conclusion: It seems that Se has protective effects on inflammatory indices. It can ameliorate renal IR complications which are associated with oxidative stress and inflammation.
A systematic review on the efficacy and safety of eculizumab for atypical hemolytic uremic syndrome
Authors: Azarfar Anoush , Ghorban Sabbagh Mahin , Ravanshad Yalda , Esmaeeli Mohammad , Mehrad-Majd Hassan , Oveisi Sani Azade , Ravanshad Sahar
Published: June 2019

Context: To date, several studies have been done regarding the treatment of atypical hemolytic uremic syndrome (aHUS) which discussed eculizumab as a potential treatment for this syndrome. However, the safety and efficacy of eculizumab were not fully assessed. This study aims to do a systematic review about the efficacy and safety of eculizumab in treatment of aHUS. Evidence Acquisitions: An electronic literature search was conducted to identify appropriate studies. We included all randomized trials and observational studies about using eculizumab in aHUS. Two independent reviewers extracted data from the articles according to the selection criteria. Results: Eligible studies were included in this systematic review. The literature search and reference mining yielded 571 potential relevant articles. We removed 173 articles because of duplication. We also excluded 245 articles after reviewing the titles and abstracts, and removed 61 studies because the topics were not relevant to the subject. Finally, five studies were included in the systematic review. Conclusions: Acknowledging the limitations of the study due to the size and nature of the included studies, our systematic review shows that eculizumab was effective in the treatment of aHUS. However, further large randomized trials are suggested.
Hypertension in adult polycystic kidney disease: a narrative review
Authors: Mian Sarah , Acharya Yogesh , Dahal Ranjan
Published: June 2019

Autosomal dominant polycystic kidney disease (ADPKD) is an inherited renal disorder that impacts approximately 12 million worldwide. It is characterized by bilateral kidney enlargement and cystic growth. Hypertension (HTN) is a focal point in the management of ADPKD and is linked to a faster progression to end stage renal disease. Current novel therapies have proven to reduce the progression of renal damage. The ideal goal is to minimize risk through preventative studies and pharmacology to further increase life expectancy and quality. The purpose of this article is to highlight the importance of blood pressure management in ADPKD and review current literature to determine the most effective preventative pharmacotherapy.
The attenuative effects of oral resveratrol on renal changes induced by vanadium injection in rats
Authors: Zendeboodi Soodabeh , Esmaili Abdolhamid , Movahed Ali , Fatemikia Hossein , Jamshidi Ali , Nazari Matin , Heydari Hosein , Seyedian Ramin
Published: June 2019

Introduction: Resveratrol (trans-3,5,4’-trihydroxystilbene) as a polyphenol with potential antioxidant and anti-inflammatory properties is known as an effective herbal medicine in different disorders in rats. Objectives: The present study was carried out to investigate the protective effects of oral consumption of resveratrol on vanadium induced renal injury in male Wistar rats. Materials and Methods: Animals received either ammonium metavanadate (AMV, 5 mg/ kg/d, (intraperitoneally; 14 consecutive days) or resveratrol solution (10 mg/kg and 50 mg/kg, gastric gavage) along with AMV treatment. The last group received resveratrol alone (50 mg/ kg, gastric gavage) for 4 weeks. Results: AMV injection caused progressive tubular damages resembling acute tubular necrosis. Microscopic views revealed tubular attenuation and blebbing. In addition, progressive peritubular congestion of the capillaries observed while no evidence of renal fibrosis was present in trichrome staining. Further, levels of the renal transforming growth factor β1 (TGF-β1) as an index of fibrosis had no difference in treated animals as compared with the control (13.4±1.2 versus 11.24±0.93 pg/mg protein) at the P<0.05. However, in AMVtreated animals receiving the higher dose of resveratrol (50 mg/kg), the renal superoxide dismutase (SOD) activity, showed no difference as compared with the saline-treated rats (42±1.3 versus 51±1.4). Conclusions It is evident that AMV injection had no ability to induce renal fibrosis in rats while it evokes renal destructive lesions based on pathological results and enzyme levels. Moreover, our preliminary results suggest that resveratrol in high dose (50 mg/kg) could confer a minor role against AMV induced renal tubular necrosis in rats due to pathological results.