bluuebunny/crossref_metadata_2025 huggingface dataset:
Total diz artroplastisinde quadriceps kas kuvveti, diz eklem propriosepsiyonu ve quadriceps kuvvet hissi: Sağlıklı kontrollerle karşılaştırmalı bir çalışma
Authors: Uçar Büşra , Yaşa Mustafa Ertuğrul , Bayrak Ahmet , Pekince Oğuzhan
Published: June 2024

Amaç: Bu çalışma eklem propriosepsiyonunun çoğunlukla ekstraartiküler proprioseptörler tarafından sağlandığı total diz artroplasti (TDA) cerrahisi geçiren bireyler ile sağlıklı kontroller arasında quadriceps kas kuvveti, diz eklemi propriosepsiyonu ve quadriceps kuvvet hissinin karşılaştırılması ve quadriceps kas kuvveti ile diz eklem propriosepsiyonu ve quadriceps kuvvet hissi arasındaki ilişkinin incelenmesi amacı ile planlandı.
Yöntem: Bu çalışmaya en az dört ay önce TDA cerrahisi geçirmiş 46 birey (ortalama yaş: 67, %80,4 kadın) ve benzer yaş aralığında 46 sağlıklı kontrol (ortalama yaş: 63, %73,9 kadın) dahil edildi. Quadriceps kas kuvveti maksimal izometrik kasılma testi ile, diz eklemi pozisyon duyusu (aktif ve pasif olarak) yeniden konumlandırma hata testi ve quadriceps kası kuvvet hissi kuvvet hassasiyet testi ile değerlendirildi. Tüm değerlendirmelerde izokinetik dinamometre kullanıldı.
Bulgular: Total diz artroplasti grubunda quadriceps kuvveti (p<0,001), aktif ve pasif eklem pozisyon hissi (tüm p<0,001) ve quadriceps kuvvet hissi (p=0,023) sağlıklı kontrollere göre anlamlı olarak az idi. TDA grubunda quadriceps kas kuvveti ile proprioseptif ölçümler arasında ve kontrol grubunda quadriceps kas kuvveti ile quadriceps kuvvet hissi arasında anlamlı bir ilişki bulunmazken (tüm p>0,05), kontrol grubunda quadriceps kas kuvveti ile quadriceps kuvvet hissi arasında düşük düzeyde negatif bir ilişki tespit edildi (p=0,007, rho=-0,391).
Sonuç: Çalışmamızın sonuçları kuvvetli bir kasın aynı zamanda duyusal açıdan zengin olmayabileceğine ve bu yüzden bir kasın değerlendirilmesi ve tedavi süreçlerinde kuvvet bileşenine ek olarak kasın proprioseptif fonksiyonunun ayrıca ele alınması gerektiğine dair ipuçları sağlamaktadır.
The Virgin’s Body and the Sheikh’s Head
Authors: Valtchinova Galia
Published: June 2024

The village of Bansko, in the Republic of North Macedonia, is known in historical-ethnological studies for its Muslim heterodox community. The Eastern Orthodox Macedonian community in the village started to gain visibility since the 1950s, to become dominant in the last decades. The village provides a good example of how the dynamics of religious communities living together is revealed through the activities of local religious virtuosi, who interpret and even may influence processes of peaceful or conflictual coexistence. This article is based on fieldwork conducted between 1999 and 2006, primarily focusing on a local female Christian-Orthodox seer whose activities, based on dream revelations, led to a Christian-Orthodox re-interpretation of the local religioscape. The latter consists in a dense network of Christian and Muslim holy places, whose making is evoked through legends and narratives of dreams and visions. Here, the legends around a miracle-working icon of Theotokos believed to be the Virgin’s body, and the disputes over the wooden sculptured head of a sheik that marked the place of his tomb, are used as metaphors to describe the shifting relationship between the two religious communities over time.
Multi-sited Ethnography on a Nexus in Religioscape
Authors: Reuter Evelyn
Published: June 2024

This article focuses on how and why to investigate shared religious places with the methodological approach of multi-sited ethnography. Places can be considered as interconnected nexuses in space that reveal social relations. In consequence, shared religious places are nexuses where various religious traditions manifest. Several places are connected by various religious groups, for example by visiting and building a network within the religioscape of a region. Researchers should consider this interconnection of places during their field research by frequenting connected nexuses. Thus, they are able to contextualize single shared religious places within the religioscape. This article aims to illustrate this methodological approach of multi-sited ethnography to investigate interconnected nexuses within a religioscape. This study exemplifies this approach using the case study of the St Naum monastery which is located in North Macedonia and visited by Christians and Muslims from various ethnic groups of this region. Hence, this article tackles the aim by asking: What is the religioscape of the St Naum monastery? Which places are connected with this monastery? And what information is gained about the monastery by frequenting the other places? This study is complemented by my experiences during field research in Macedonia, Albania and Kosovo.
Historical Narratives and Spatial Strategies of Reappropriation in Three Romanian Orthodox Monasteries
Authors: Tateo Giuseppe , Cozma Ioan , Massenz Giulia
Published: June 2024

Contrary to the abundance of shared religious places throughout south-eastern Europe, multi-religious interaction is not a regular feature in Romania. Pilgrimages and visits to the popular Orthodox monasteries of Prislop and Nicula in Transylvania and Dervent in Dobruja are an exception to this trend. Unsurprisingly, these two regions are historically characterized by a remarkable ethnic and religious diversity. The two Transylvanian monasteries attract practitioners of different Christian denominations (Orthodox, Greek-Catholic, Roman-Catholic and Evangelical), while Dervent is a devotional site for Christians and Muslims (Tatars, Turks and Roma) alike. Common to all three monasteries is the presence of allegedly miracle-working objects, artefacts and bodies: a stone cross at Dervent, the Virgin Mary icon at Nicula, and the tomb of the charismatic monk Arsenie Boca at Prislop, respectively. Based on ethnographic fieldwork conducted in the three monasteries during both important feasts and everyday monastic life, this article is a multidisciplinary exploration of the workings of inter-religious competition, sharing and interaction. It combines the methods typical of ethnographic research with observations on how the religious space is navigated and socialized through the support of cartography and archival satellite images. The article casts light on how the historical narratives and spatial strategies enacted by the Romanian Orthodox Church overlap in the attempt to reclaim legitimate ownership and exclusive primacy over three popular devotional sites with a composite ethnic and religious past.
Philip P. Arnold, The Urgency of Indigenous Values
Authors: Wright Robin M
Published: June 2024

Philip P. Arnold, The Urgency of Indigenous Values (Syracuse, NY: Syracuse University Press, 2023), 269 pp., $29.95 (e-book), ISBN: 978-0-8156-5690-6.
Chemical potential and biomedical activity of gold nanoparticles in cancer and drug delivery systems: an updat
Authors: Soni Sandeep Kumar , Solanki Dr. Manoj Kumar
Published: June 2024

Gold nanoparticles (AuNPs) are broadly utilized in medical fields because of its unique potential, biomedical activity and physicochemical properties. The biocompatible nature, optical properties, and minor cytotoxicity are the key features of AuNPs which make them valuable for biomedical applications. Today, AuNPs are widely used for cancer therapy, bioimaging, biosensing, radiotherapy, photodynamic therapy and drug delivery system. The present article illustrates the current progress in AuNPs synthesis, properties of AuNPs, various biomedical activity of AuNPs in therapeutic fields and drug delivery systems. Apart from numerous benefits the chemically synthesized AuNPs also creates certain level of toxicity in the living system which represents confronts of AuNPs against biomedical applications. Reducing its cytotoxic nature and development of green AuNPs can led to development of new history in field of medical science and clinical trials. Thus, the present review article deals with the compiled study of various fundamental research over AuNPs such as its chemical and bio-synthesis, biomedical and therapeutic applications viz. plasmonic photothermal therapy, photodynamic therapy, folate receptor targeting, targeted drug delivery etc. The article also finds some of its confronts against biomedical application because of its cytotoxic nature and its possible future prospects.
AMARANTH: PROBLEMS AND PERSPECTIVES OF PROCESSING
Authors: Sots S. , Kustov I. , Lapinska А. , Kotsiuk А. , Chehlatoniev V.
Published: June 2024

Amaranth is one of the ancient, so-called pseudo-cereal crops, the first mentions of it date back more than 8,000 years. Despite the sufficiently high study of amaranth and its wide distribution, according to the volume of its cultivation, it can be classified either as a niche crop or as a special purpose crop. Amaranth can be attributed to small-seeded grain crops, the grain has a rounded lenticular, oval-rounded shape with a diameter of 0.9 to 1.7 mm, the weight of 1000 grains is in the range of 0.6 to 1.1 g. Amaranth grains can be white, red, golden, black, or brown in color, with the white grain having the highest manufacturability. In Ukraine, up to 50 enterprises are engaged in the processing of amaranth, while receiving oil, cereals, flakes and flour, but at the moment, despite the high usefulness of these products, a permanent circle of its consumers has not yet been formed in our country, which in turn affects the volume of amaranth cultivation and volumes of its processing into food products. 15 varieties of amaranth are included in the register of plant varieties suitable for distribution on the territory of Ukraine, among which seven varieties are intended for grain. Sterkh, the forage amaranth variety, was the first to enter the Register... in 1994. In the following year, 1998, three amaranth varieties Atstek and Ul'tra and Kremovyi rannii were registered. It should be noted that the first two varieties are grain requirements according to the recommendations of the Register..., and the Kremovyi rannii variety is a fodder variety. In 1999, two more grain varieties of amaranth, Orkhideia and Polischuk, were registered. In 2000, the grain requirements variety Zhaivir was registered. In 2003, the Liera and Sem grain requirements varieties were registered, and in 2009, the Students'kyi variety. Indirectly, amaranth can be characterized by a mass fraction of protein up to 19%, fat up to 9%, carbohydrates up to 60 %, fiber up to 4 %, ash up to 3 %. An impeding factor in increasing the volume of amaranth grain processing is the lack of approved regulations and the lack of enterprises with the appropriate understanding of how to effectively clean amaranth grain from impurities, carry out dehulling, sorting of dehulling products and, most importantly, what kind of product range to produce. All this stops the wide spread of this crop in our country and, accordingly, amaranth products are not widely distributed compared to other traditional crops and are not well known to the domestic consumer.
WHEAT FLOUR QUALITY CORRECTION BY USING ENZYME PREPARATIONS
Authors: Zhygunov D , Chumachenko Yu , Kovalov M , Kovalova V
Published: June 2024

Over the past decade, the flour milling industry has been undergoing active development, with the reconstruction of existing enterprises and increased construction of new flour mills under conditions of declining quality of incoming raw materials, high competition and low profitability of bakery enterprises and flour mills. Therefore, such enterprises should be able to produce not only standard flour but also flour with specified quality indicators. One example is flour with enhanced baking properties intended for special product groups such as loaves, baguettes, buns, etc. Standard Ukrainian flour, produced due to its low protein and gluten content, cannot always be used for these products. The aim of the study was to investigate the effect of a protease-acting enzyme preparation on the gluten network of flour and to develop a complex-acting technological additive. To study the quality of flour, both conventional and innovative evaluation methods were used with the help of the Mixolab device, and trial laboratory baking of samples was carried out. To improve the protein-proteinase complex, the enzyme preparation Neutrase 15 BG was used in three dosages: minimum (0.02 g/kg), medium (0.06 g/kg) and maximum (0.1 g/kg). For complex action, a mixture of enzyme preparations Neutrase 15 BG and Fungamyl 2500 SG in the following dosages: 0.02 g/kg + 0.002 g/kg; 0.02 g/kg + 0.005 g/kg; 0.02 g/kg + 0.01 g/kg. The paper analyses the quality of flour produced by Ukrainian producers, determines the effect of a proteolytic enzyme on the quality characteristics of gluten, evaluates the baking properties of graded flour with a proteolytic enzyme, and develops a technological additive to adjust the protein-proteinase complex of flour. The analysis of previous studies has shown that high-grade flour from the Southern region is characterised by low quality, namely a low gluten content of 24.0-25.2% with excessively resistant gluten properties of 47-60 units, and low amylolytic activity – the falling number is above 460-480 s. It has been established that at the minimum and average dosage of Neutrase 15 BG, the specific volume of bread increased by 0.5% and at the maximum – by 0.2%, with a clear deterioration in organoleptic characteristics. Therefore, it makes sense to use this enzyme in low dosages to prevent stickiness of the dough. According to the results of the influence of the technological additive on bread quality indicators, it has been found that in the sample with the following dosage of Neutrase 15 BG and Fungamyl 2500 SG – 0.02 g/kg + 0.01 g/kg, respectively, the volume and porosity of bread increased by 1.3 times and 1.1 times, respectively.
MACHINE LEARNING-BASED PREDICTIONS OF NANOFLUID THERMAL PROPERTIES
Authors: Oh Youngsuk , Guo Zhixiong
Published: June 2024

In this study, machine learning-based predictions of thermal conductivity, dynamic viscosity, and specific heat of
nanofluids are explored. Various types of nanofluids and parametric conditions are considered to broaden and evaluate
the effectiveness of popular machine learning models, including multilayer perceptron, random forest, light gradient boosting machine, extreme gradient boosting, and stacking algorithms. The performance of these prediction models is assessed using the mean squared error and the coefficient of determination. The influence of each input variable on model development was examined to identify key features. Information gain is introduced and calculated for determining the importance of parameters in prediction. External validation is performed with an additional unseen dataset to further assess the applicability of the selected models across different experimental data points. It was found that the stacking technique is the most accurate machine learning algorithm among those investigated. The LightGBM is the top choice when considering both computational accuracy and efficiency. The results demonstrate that machine learning methods can provide excellent predictions of the thermophysical properties of complex nanofluids.
Liver venous deprivation in the prevention of post-resection hepatic failure
Authors: Sudakov M. A. , Shchekoturov I. O. , Vasilenko E. I. , Cholak P. M. , Emelyanova A. S. , Savostyanov K. A. , Egorov A. V. , Vetshev F. P.
Published: June 2024

The paper presents a clinical observation of successful X-ray endovascular intervention performed in a patient with colorectal cancer metastases in the liver in order to prevent post-resection hepatic failure. Traditional embolization of the right branch of the portal vein was supplemented by occlusion of the right hepatic vein. Venous deprivation enabled a rapid growth of the future liver remnant to be achieved as indicated by CT volumetry results and SPECT-CT data that showed a significant increase in hepatic clearance. The first results demonstrate that liver venous deprivation is to be investigated further in clinical practice.
Endoscopic stenting of the common bile duct in choledocholithiasis in a 10-year-old child: a clinical observation
Authors: Schebenkov M. V. , Volert T. A. , Orlov O. U.
Published: June 2024

The paper describes a clinical observation of extrahepatic cholestasis in a 10-year-old child. Anatomical features required complex endoscopic surgery. The patient with jaundice and pain syndrome was hospitalized in the state of moderate severity with the history of the disease for more than a month. The study presents stages of outpatient and clinical laboratory and instrumental diagnostics. As a result, obstructive jaundice was revealed. Multi-stage endoscopic treatment was successfully performed. It revealed no signs of choledocholithiasis, but detected compression of the pancreatic part of the common bile duct without pathological changes in the head of the pancreas. Endoscopic stenting of the common bile duct and pancreatic duct was performed. Biliary hypertension was eliminated. Endoscopic methods of biliary decompression can be applied to older children. Pancreatic duct stenting can be performed to prevent postoperative pancreatitis. Atypical sphincterotomy provides access to the bile ducts.
Gestión empresarial del talento humano desde la política de responsabilidad social. Una revisión sistemática
Authors: Ramírez Torres William Eduardo
Published: June 2024

La responsabilidad social empresarial es una política enmarcada en la ética de las buenas prácticas competitivas y productivas de las organizaciones en los diferentes entornos socioculturales y económicos globales. Objetivo. Analizar la eficiencia de las actividades administrativas de la gestión del talento humano del sector empresarial en los diversos contextos laborales. Metodología. La metodología de esta investigación corresponde a un análisis descriptivo de la temática con base en la revisión sistemática de evidencia científica de literatura especializada, integrándose el procedimiento PRISMA a este proceso. Resultados. Los resultados muestran la importancia de alinear estratégicamente al personal con los objetivos misionales de las empresas. Se enfatiza en la integración y práctica de los derechos sociales y laborales en los subsistemas de bienestar laboral, los entornos laborales saludables y la inversión financiera. Conclusiones. Las conclusiones del estudio señalan elementos clave de éxito para una gestión del personal eficaz con base en la gestión del conocimiento sostenible en función de los procesos de compensación, capacitación y entrenamiento, así como la promoción del capital humano y social de las personas.
Bir Harabe Şehrin Kaybolan Mabetleri: Eski Rumkale Merkezinde Cami ve Mescitler
Authors: Taş Yasin
Published: June 2024

Günümüzde harabe haldeki Rumkale kalesi, ilk çağlardan beri Fırat Nehri kenarındaki korunaklı yerleşim alanlarından biridir. Orta çağda Haçlı seferlerinin etkisiyle Ermeni ve Yakubilerin katikosluk merkezi haline gelen bu şehir, geleneksel Hıristiyan inancında mühim bir mevki edindi. Memlukler tarafından fethedildikten sonra bir İslam beldesi hüviyetini aldı. Osmanlı döneminde vakıf sistemi içinde inşa edilen cami, mescit, medrese ve zaviye gibi yapılar, birkaç asır şehrin hâkim kültürü haline gelerek sosyal hayatı şekillendiren başlıca müesseseler oldu. 19. yüzyılda kale beylerinin bir takım isyan ve taşkınlıkları ile Kavalalı olayının yarattığı tahribattan dolayı kale yerleşime kapatılarak boşaltıldı. Terk edilen kale zamanla harabe hale geldiği gibi buradaki mabetler ve vakıf eserler de tamamen yıkılarak kayboldu. Rumkale’deki vakıf yapıların bölge halkı tarafından neredeyse tamamen unutulmuş olması ve Birecik Barajının yapımıyla kale etrafındaki yerleşim harabelerinin sular altında kalması buradaki vakıf kültürünü ortaya çıkarmayı zaruri kılmaktadır. Diğer yandan 19. yüzyılda Rumkale’yi ziyaret eden batılı gezginlerin harabelerdeki kilise ve manastır kalıntılarını öne çıkaran anlatıları, modern dönem araştırmalarında şehrin mimari yapıları için başlıca referanslar halini almıştır. Rumkale’nin tarihi süreçteki şehir kimliği, dönem ayrımı yapmayan akademik çalışmalarda Hıristiyan mabetler üzerinden pekiştirilmektedir. Son yıllarda kale harabelerine dair envanter çalışmalarında benzer şekilde kilise ve manastır kalıntılarının ön plana çıktığı buna mukabil Müslüman mabetlerin ismen dahi tespit edilemediği dikkat çekmektedir. Şehrin Memluk ve Osmanlı dönemlerinde edindiği yeni kimliği doğru bir şekilde ortaya koymak için burada inşa edilen Müslüman mabetlerin tarihi kayıtlar ışığında tespit edilmesine ihtiyaç vardır. Bu çalışmada Osmanlı arşiv kaynaklarına yansıyan kayıtlar ışığında başta Ulu Camii olmak üzere Rumkale yerleşim alanındaki tarihi cami ve mescitlerin tespit edilmesi, inşa dönemleri, görevlileri, hizmet sahaları, vakıf kaynaklarının belirlenmesi ve bazı eski resmilerinin ortaya konulması amaçlanmaktadır. Cami ve mescitlerin herhangi bir vakfiyesi günümüze ulaşmadığından çalışmanın temel kaynaklarını Osmanlı’nın bölgeyi ilhakından sonra düzenlenen tahrir defterleri, vakıf atama kayıtlarını ihtiva eden hurufat defterleri, vakıfların gelir giderlerini yansıtan vakıf muhasebe defterleri ve evkaf fonundaki diğer arşiv malzemesi oluşturmaktadır.
Permissible People Smuggling and the Duty of Rescue: Insights from Backstreet Abortion
Authors: Zuccarelli Gloria
Published: June 2024

Migrant smugglers are portrayed as pure evil, driven only by greed, as they are blamed for the death and suffering of thousands of migrants. Similarly, backstreet abortionists have been the object of universal condemnation. Yet they are the only hope and means for refugees and women when border crossing and voluntary interruptions of pregnancy are not legally available. Drawing on the analogy with backstreet abortion, in the first part of this article I argue that migrant smuggling is justified in the context of a systemic violation of the human right to seek refuge (e.g. criminalisation of border crossing and SAR operations), provided that a number of procedural constraints are met. In the second part of this article, I go one step further and argue that under the extremely non-ideal conditions outlined above, smuggling becomes a humanitarian, and therefore cost-related, duty which binds organisations, whereas it only indirectly applies to individuals.
CRE Redevelopment Options and the Use of Mortgage Financing
Authors: Glancy David , Kurtzman Robert , Loewenstein Lara
Published: June 2024

A significant share of commercial real estate (CRE) investment properties---about half by our estimates---are purchased without a mortgage. Using comprehensive microdata on transactions in the U.S. CRE market, we analyze which types of properties are purchased without a mortgage, highlighting the important role of renovation or redevelopment options. We show that mortgage-financed properties are less likely to be subsequently redeveloped, and that owners anticipate these redevelopment frictions and avoid mortgage financing for properties with greater redevelopment options. These effects were even stronger during the COVID-19 pandemic, when uncertainty increased redevelopment option values.
First report of Ecclitura primoris Kokujev, 1902 in Hungary (Hymenoptera: Braconidae)
Authors: De Ketelaere Augustijn , Magyar Botond
Published: June 2024

Ecclitura primoris Kokujev, 1902, the sole European species of the genus Ecclitura Kokujev, 1902 (Hymenoptera: Braconidae: Euphorinae) is reported for the first time from Hungary, representing its northernmost record and first occurrence outside the Mediterranean area in Europe.
أثر اختلاف القراءات والوقف والابتداء على تنوع المعاني في قصة سُليمان في سورة النَّمل
Authors: Eıd Israa Mahmood Eıd
Published: June 2024

إنّ تعدد القراءات مما تميّز به القرآن الكريم عن غيره من الكتب السماوية الأخرى، ويُعدُّ علم القراءات من أهم العلوم التي تُعين المُفسر على التفسير الصحيح، وقد جاء هذا البحث ليُسلط الضوء على اختلاف القراءات المتواترة والشاذة معًا في قصة سُليمان عليه السلام في سورة النَّمل، وأثر ذلك الاختلاف في توسُّع المعنى، وإثراء دلالاته، وقد بلغت عدد المواضع المختلف فيها أكثر من عشرين موضعًا تقريبًا، بعضها نتج اختلافه من لهجات العرب ولغاتهم ولا أثر له في المعنى، وبعضها الآخر له أثر بَيّن في المعنى، كما سلط البحث الضوء على مواضع الوقف والابتداء المختلف فيها بين العلماء وأثر ذلك في المعنى أيضًا، ومما ظهر جليًا في البحث أن اختلاف القراءات يوسّع المعنى بلا تضاد ولا تناقض، بل يؤيد بعضها بعضًا لإظهار جمال الإعجاز وكمال البلاغة في القصة.
Flora vascular y descripción de la vegetación de un bosque tropical caducifolio del municipio de Nocupétaro, Michoacán, México
Authors: Valentín Martínez Dagoberto , Silva-Sáenz Patricia , González-González Yuretzi
Published: June 2024

Background: Tropical deciduous forest possesses high levels of biodiversity; however, there is not a complete floristic survey of this ecosystem in the municipality of Nocupétaro, Michoacán.
Questions: Which species are present in the study area? Which species are endemic to Mexico and how many are at risk? With which area does it have the greatest floristic affinity?
Studied species: Vascular plants.
Study site and dates: An area of tropical deciduous forest occurring in the municipality of Nocupétaro, Michoacán, Mexico; September 2016 to November 2017.
Methods: Specimens were collected in the field and determined using pertinent specialized literature. The vegetation was defined using physiognomy and dominant species.
Results: Fifty-six families, 135 genera, 173 species, and eight infraespecific taxa were registered. The families with more species were Fabaceae (34 spp.), Asteraceae (12 spp.), Euphorbiaceae (11 spp.), Apocynaceae (9 spp.), Malvaceae (8 spp.), and Convolvulaceae (7 spp.). The most speciose genera were Euphorbia (6), Senna (6), Ipomoea (5), and Bursera (4). Forty-five species are endemic to Mexico; two are listed in the NOM-059-SEMARNAT-2010 and three species are included IUCN Red List with a risk category. The area has a greater floristic affinity with the Parotita hill.
Conclusions: The information generated is the basis for other research (ecological, fauna) and stand out the importance of continuing to study and conserve this ecosystem in the region.
Animal-assisted education: Perception of teachers and parents on the impact of the DOG project
Authors: Riki Verhoeven , Rob Martens , Marie-José Enders-Slegers
Published: June 2024

Introduction: Research regarding Animal-Assisted Education (AAE) is a relatively new field. Due to the growing number of programs in the field, investigating AAE interventions is important. The aim of this study was to gain insight into teachers’ and parents’/caregivers’ perceptions of the impacts of a specific form of Animal-Assisted Service (AAS, formerly Animal-Assisted Intervention (AAI) namely, an Animal-Assisted Education (AAE) program for primary school students, as offered in the Netherlands. Materials and methods: This study was designed as an exploratory qualitative study, executed by means of interviews using a semi-structured questionnaire. Twelve teachers and ten parents/caregivers were interviewed. The analysis started with open coding and was followed by axial and selective coding. Results: There is significant agreement regarding the positive influence of AAE on the perception of teachers and parents. Both notice an impact beyond the context of the AAE sessions in the areas of communication, social-emotional development, self-confidence, and environmental factors. Teachers also note that the AAE project has provided them with insights that influence their professional development. Conclusion: It can be cautiously stated that 10 sessions, according to the DOG project, had a positive impact on the social-emotional development of elementary school students according to their parents and teachers. Further research on what AAE means for students is recommended. Considering the unforeseen and impactful outcome of this playful interaction initiative on teachers, it is advised to conduct subsequent research to further explore the underlying mechanisms, aiming to enhance the professional development of teachers.
Safety and Efficacy of Sodium-Glucose Transport Protein 2 Inhibitors and Glucagon-like Peptide-1 Receptor Agonists in Kidney Transplant Recipients: Synthesis of Evidence v1
Authors: Bellos Ioannis , Benetou Vassiliki
Published: June 2024

A systematic review and meta-analysis will be conducted aiming to investigate the efficacy and safety of Sodium-Glucose Transport Protein 2 inhibitor (SGLT2-i) and Glucagon-like Peptide-1 Receptor Agonist (GLP1-RA) treatment in kidney transplant recipients, with and without diabetes mellitus. A systematic literature search will be performed and the quality of the included studies will be critically assessed using validated tools. Statistical meta-analysis will be performed using random-effects models and exploring potential sources of heterogeneity. The certainty of the existing evidence will be critically evaluated following the GRADE approach.
Lysosomal activity DQ-Red BSA assay v1
Authors: Karim Razaul
Published: June 2024

This protocol details the Lysosomal activity DQ-Red BSA assay.
Genetic improvement in Colombian cattle, a reality or an intention? A review
Authors:   Universidad de Ciencias Aplicadas y Ambientales U.D.C.A, Amaya Alejandro , Cotes-Torres José-Miguel ,   Universidad Nacional de Colombia
Published: June 2024

Background: Genetic improvement programs in domestic species require a set of steps involving the definition of breeding objectives, information systems, variance component estimation, genetic evaluations, selection indexes, and the estimation of genetic progress and variability. Objective: To identify strengths and weaknesses in the design and implementation of genetic improvement programs in Colombian cattle through scientific and academic contributions derived from research. Conclusion: The greatest challenges in the design and implementation of genetic improvement programs in Colombian cattle are currently related to the absence of consensus breeding objectives among farmers and associations. Additionally, there is a need in the short term to improve both the quality and quantity of information available in databases. Finally, conducting economic analyses that consider genetic parameters is essential for optimizing the response to genetic selection, considering the different productive systems and environmental conditions that Colombia offers.
A Latent Class Analysis Approach to Challenges Experienced by Faculty Members in Online Assessment in Higher Education
Authors: Gül Emrah
Published: June 2024

Online assessment is the use of computer technologies by faculty members to guide and check learning. Taking the advantage of technology, many universities have used online assessment applications to ensure sustainability in education due to the pandemic and natural disasters. The purpose of the current study is to explore challenges experienced by faculty members in online assessment, using latent class analysis. The descriptive design research was carried out with the participation of 105 faculty members. For the study, the number of latent classes was decided according to the Akaike Information Criterion (AIC) and the Bayesian Information Criterion (BIC) and it was observed that the data structure was a good fit for a two-class model. According to the research results, the first class in online assessment applications was considered as the with-difficulty group (58.7 %) and the second as the without-difficulty group (41.3 %). When the conditional probabilities were examined, it was concluded that the observed variables that mostly contributed to the two-class model data structure were as follows, cheating, plagiarism and lack of education policies. It was found that the primary challenges in both groups (with or without difficulty) in online assessment applications were cheating, plagiarism and lack of education policies.
Repensando o Nascimento como um Direito Integral na Luta contra a Violência Obstétrica no Brasil
Authors: Pantoja Jessica Corrêa , Batisti Mateus Batista , Pereira Maria Clara de Araújo Rodrigues
Published: June 2024

Objetivo: analisar o impacto da ausência de legislação federal e normativas na mitigação da violência obstétrica no Brasil, por meio de uma análise crítica, com ênfase na regulação legal. Metodologia: inicialmente, realizou-se uma revisão narrativa de abordagem qualiquantitativa e exploratória-descritiva nas bases de dados da Biblioteca Virtual em Saúde e da Scientific Electronic Library Online, no período entre 2018 e 2023. Os artigos foram selecionados utilizando descritores do Medical Subject Headings, como “obstetric violence” e “violence against women”, combinados através do operador booleano “AND”. Posteriormente, foi conduzida uma pesquisa documental buscando consultar a legislação estadual vigente no Brasil e identificar possíveis lacunas. Resultados: Identificou-se uma lacuna considerável em relação à violência obstétrica e à conscientização limitada sobre os direitos à autonomia das mulheres, que são preocupações evidentes. Em relação às legislações estaduais analisadas, 14 fazem menção à “violência obstétrica” e 8 abordam a “humanização do parto”. Dessas, 19 têm caráter informativo, 28 são preventivas e 2 são punitivas. Considerações Finais: A ausência de consenso na definição da violência obstétrica e a escassa capacitação dos profissionais de saúde resultam em práticas obsoletas. A elevada taxa de cesarianas desnecessárias e a carência de estudos sobre mulheres quilombolas e indígenas são preocupantes. No âmbito jurídico, a falta de compreensão por parte dos magistrados e a fragmentação das legislações estaduais representam desafios significativos. Torna-se crucial adotar uma abordagem multidisciplinar e políticas públicas claras para prevenir essa violência e assegurar uma assistência ao parto segura e centrada nas necessidades das mulheres.
Submissão: 29/02/24| Revisão: 17/05/24| Aprovação: 18/05/24
Aprimoramento da Estrutura Normativa: a consolidação de normas do SUS e as atualizações do Decreto nº 12.002, de 2024
Authors: Lemos Amanda Nunes Lopes Espiñeira , Alves Sandra Mara Campos Alves
Published: June 2024

O processo de consolidação depende de uma boa redação e elaboração dos atos normativos e é consequência inerente do aprimoramento de normas. Nesse sentido, apresenta-se as inovações do Decreto n.º 12.002, de 2024, relativas à consolidação, que dizem respeito, sobretudo, à obrigatoriedade de manutenção da consolidação normativa por meio da realização de alteração da norma consolidada e de medidas periódicas de revisão dessas normas. Essa manutenção constante dos atos consolidados preserva a necessidade de melhoria normativa, essencial para garantir segurança jurídica, transparência no ambiente democrático e cumprir as determinações da Organização para a Cooperação e o Desenvolvimento Econômico voltadas para política regulatória. A saúde, como pioneira no processo de consolidação dos seus atos normativos infralegais, tem a vanguarda no aprimoramento de normas e deve ser exemplo para outros órgãos.
Tapestries of Topics: Factors Affecting the Issue Diversity of Political Parties’ Social Media Campaigns
Authors: Magin Melanie , Larsson Anders Olof , Skogerbø Eli , Tønnesen Hedvig
Published: June 2024

For citizens to make well-informed decisions, they require information on diverse policy issues, which, among others, are publicized on political parties’ social media accounts. However, as strategic actors, parties carefully weigh which issues to highlight and which to play down, rather than addressing a full range of issues in their campaigns. We investigated the hitherto neglected question of which issue diversity parties prioritize on their social media accounts and which factors influence this choice. We conducted a standardized content analysis of the official Facebook, Instagram, and Twitter accounts of 10 Norwegian parties and their leaders during the 2021 national election campaign. The results of our analyses indicate that issue-related campaign strategies influence parties’ issue diversity more systematically than parties’ governing/opposition statuses and their choices of social media platforms.
Treatment of spinal lesions in breast cancer patients (literature review)
Authors: Rascheskova K. K. , Khasanov R. Sh. , Safin I. R. , Safin R. N.
Published: June 2024

Breast cancer is one of the most significant problems in oncology. This pathology is characterized by increased risk of fractures associated with postmenopausal decrease in bone mineral density, use of hormone therapy, and presence of osteolytic metastases in the spine. All these factors can cause non-traumatic spine fractures decreasing patient mobility and leading to permanent pain syndrome and neurologic deficit.

The article presents the modern view on the osteoporosis problem and risk of non-traumatic spine fractures in patients with breast cancer and spine metastases. Literature data on predictors of pathological bone fractures, as well as time and risk of spine metastases in these patients are analyzed. Data of modern studies on the effectiveness of various methods of breast cancer treatment and their combinations, as well as possibilities of minimally invasive surgical interventions, antiresorptive and radiological therapy are considered.
The Effectiveness of Radiofrequency Thermal Ablation in the Treatment of Patients with Osteoid Osteomas of the Spine
Authors: Kuznetsov S. F. , Babkin N. S. , Kabardaev R. M. , Borzov K. A. , Sofronov D. I. , Katarova A. V. , Valiev A. K.
Published: June 2024

Osteoid osteoma is a rare benign osteogenic bone tumor without malignant potential causing severe night pain relieved by nonsteroidal anti-inflammatory drugs. Pain associated with osteoid osteoma of the spine cannot be treated conservatively and requires surgical approach. Types of surgical treatment include intralesional curettage, marginal resection, or en bloc tumor resection. However, absence of clear intraoperative visualization of the lesion often leads to excessive resection of vertebral structures requiring additional bone reconstruction and fixation with metal structures. In some cases, due to incorrect choice of resection area and segment level, repeat surgeries are performed causing secondary spinal deformations, worsening patient’s condition, and increasing economic expenditures. Currently, minimally invasive methods of transcutaneous treatment of osteoid osteomas such as interstitial laser ablation, cryotherapy, and radiofrequency thermal ablation are becoming more prominent.

Aim. To evaluate the effectiveness of radiofrequency thermal ablation treatment in patients with osteoid osteoma.

Materials and methods. The prospective study included 12 patients with osteoid osteoma of the spine. Their quality of life was evaluated using the Short Form-36 (SF-36) questionnaire prior to radiofrequency thermal ablation and 30, 90 and 180 days after. At the first visit and during observation, pain syndrome intensity was measured using the Visual Analog Scale (VAS) and R.G. Watkins scale for objective evaluation of pain syndrome per number of analgesics administrations.

Results. Follow-up duration varied between 12 and 36 months. In all clinical cases, general, physical, and psychological health improved 2–3-fold. Pain intensity at day 1 after radiofrequency thermal ablation compared to mean pain intensity during the day prior to the procedure was significantly lower (р = 0.05). At the final examination, none of the patients had pain (pain syndrome intensity 0 per VAS); all patients had subjective satisfaction level of 100 %. Analgesics (nonsteroidal anti-inflammatory drugs and paracetamol) were administered on request for 8 ± 2.34 days after the procedure.

Conclusion. Based on literature data and our own experience of diagnosis and surgical treatment of osteoid osteoma of the spine, we conclude that in cases of small lesions (<2 cm) in hard to access locations, computed tomography-controlled radiofrequency thermal ablation allows to perform surgical intervention safely, effectively and with minimal number of complications.
Classification of the Volume of Tumor Lesion of the Chest Wall as A Prerequisite for Planning Surgical Treatment
Authors: Valiev A. K. , Salkov A. G. , Fedorova A. V. , Efimenko O. , Eltsov I. V.
Published: June 2024

Tumors of the chest wall are a heterogenous group of neoplasms per nosology, clinical progression, and treatment methods. Primary tumors of this location, according to some authors, comprise between 1 and 5 %, and 60 % of them are malignant. Tumors of the chest wall can have not only various nosological forms but also varying volume, location, affect different structures of the chest wall which are determined during physical exam. Despite the progress in drug therapy, radical surgical intervention is a prerequisite for successful treatment of patients with malignant tumors of the chest wall. One of the most important prognostic factors is sufficient margin during chest wall resection. The international tumor classification system Tumor, Nodus and Metastasis (TNM) does not give a complete understanding of the volume of lesions and therefore does not allow to correctly plan resection volume and defect reconstruction based on its data.

The article presents a classification of tumor volume of the chest wall proposed by the Sarcoma Research Association which allows to expand indications for surgical treatment and select the optimal type of defect reconstruction.
Sentinel Lymph Node Biopsy in Cutaneous Melanoma: Results of a Single-Center Analysis
Authors: Musin Sh. I. , Zamilov M. M. , Menshikov K. V. , Sultanbaev A. V. , Yatsenko T. G. , Sharifgaleev I. A. , Metelev V. A. , Sultanova A. R. , Sharafutdinova N. A. , Nasretdinov A. F. , Nguyen H. , Sangisheva M. S. , Ayupov R. T. , Izmailov A. A. , Osokin S. V.
Published: June 2024

Sentinel lymph node biopsy (SLNB) in cutaneous melanoma is a staging step in cases of unaffected regional lymph nodes. This method is included in routine practice in many medical facilities of the Russian Federation.

Aim. To analyze the results of SLNB in cutaneous melanoma performed using gamma scintigraphy technique with the 99mTc-containing technefit radiopharmaceutical agent.

Materials and methods. The prospective study included 97 patients (39.2 % (38/97) men and 60.8 % (59/97) women) with primary cutaneous melanoma who received surgical treatment at the Republican Clinical Oncological Dispensary (Ufa) between February of 2021 and January of 2023. Mean patient age was 57.2 ± 13.2 years (95 % confidence interval (CI) 53.8–61.3 years), mean Breslow thickness per biopsy and histological examination after wide tumor resection was 2.89 ± 2.7 mm (95 % CI 2.2–3.76 mm), median follow-up period was 14 months (interquartile range 8–18 months). 99mTc-containing technefit radiopharmaceutical agent was administered intradermally around melanoma/scar. Accumulation of the radiopharmaceutical in the regional lymph nodes was evaluated using single-photon emission computed tomography/computed tomography (SPECT/CT). Intraoperatively the sentinel lymph node (SLN) was identified using a portable gamma probe. Morphological evaluation was performed in accordance with the protocol approved at the Republican Clinical Oncological Dispensary and based on the updated protocol of the European Organisation for Research and Treatment of Cancer (EORTС) (2019).

Results. The percentage of successfully mapped SLNs after radiopharmaceutical administration was 93.8 % (91/97). Mean number of visualized SLNs per SPECT/CT data was 1.7 ± 1.1 SLN (95 % CI 1.5–1.9). SLN biopsy was performed in 91.8 % (89/97) patients. Mean number of identified SLNs during SLNB was 1.9 ± 1.2 (95 % CI 1.6–2.3). Histological and immunohistochemical examinations showed SLN metastases in 22.5 % (20/89) patients; in 77.5 % (69/89) patients, no lymph node metastases were found. SLN biopsy allowed to perform disease staging. During follow-up in 3 patients with negative SLNs metastases in the regional lymph nodes were found, as well as in 2 patients with positive SLNs. The frequency of false negative SLNB results was 13 % (3/23), negative post-test probability was 2.8 % (2/69). V600E mutation in the BRAF gene was found in 42.3 % (22/52) patients.

Conclusion. SLN biopsy using the technefit radiopharmaceutical showed satisfactory results: SLNs were identified in 93.8 % of cases. Morphological examination showed SLN metastases in 22.5 % (20/89) of patients.
Possibilities of Postoperative Rehabilitation After Combination Resection of the Pelvis with Acetabulum and Hip Joint Endoprosthesis
Authors: Erin D. A. , Derzhavin V. A. , Bukharov A. V. , Yadrina A. V. , Elkhov D. O. , Aliyev M. D.
Published: June 2024

The article presents a clinical case of successful surgical treatment of primary chondrosarcoma of the right ilium affecting the acetabulum and hip joint with acetabulum endoprosthesis. Rehabilitation measures aimed at restoration of the affected limb function are also described. After these measures, the patient demonstrated excellent functional results (93.3 % per the Musculoskeletal Tumor Society Score). Recurrence-free period was 49 months. In modern orthopedic oncology, many techniques of organ-preserving surgical treatment in patients with tumors of the periacetabular area with subsequent reconstruction are used but they are technically complex and carry high risks of postoperative complications. In our opinion, only combination of surgical techniques with interdisciplinary approach during perioperative rehabilitation allows to achieve good and even excellent functional results which is confirmed by the presented clinical case.
Non-Exponential Reverberation Modeling Using Dark Velvet Noise
Authors: Fagerström Jon , Schlecht Sebastian J. , Välimäki Vesa
Published: June 2024

Previous research on late-reverberation modeling has mainly focused on exponentially decaying room impulse responses, whereas methods for accurately modeling non-exponential reverberation remain challenging. This paper extends the previously proposed basic darkvelvet- noise reverberation algorithm and proposes a parametrization scheme for modeling late reverberation with arbitrary temporal energy decay. Each pulse in the velvet-noise sequence is routed to a single dictionary filter that is selected from a set of filters based on weighted probabilities. The probabilities control the spectral evolution of the late-reverberation model and are optimized to fit a target impulse response via non-negative least-squares optimization. In this way, the frequency-dependent energy decay of a target late-reverberation impulse response can be fitted with mean and maximum reverberation-time errors of 4% and 8%, respectively, requiring about 50% less coloration filters than a previously proposed filteredvelvet- noise algorithm. Furthermore, the extended dark-velvet-noise reverberation algorithm allows the modeled impulse response to be gated, the frequency-dependent reverberation time to be modified, and the model’s spectral evolution and broadband decay to be decoupled. The proposed method is suitable for the parametric late-reverberation synthesis of various acoustic environments, especially spaces that exhibit a non-exponential energy decay, motivating its use in musical audio and virtual reality.