bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of Heat Treatment on Fracture Behavior in ENiCrFe-7 Weld Overlay Cladding Materials
Authors: Guo Peiliang , Han H.G.
Published: August 2021

The effect of heat treatment (as-weld, 615℃/48h) on fracture behavior in ENiCrFe-7 weld overlay cladding material was investigated. There were more NbC precipitates in the interdendrites for the heat treatment one after 615℃/48h than that of as-weld, which resulted in the lattice distortion in the interdendrites reduced by the heat treatment. As a result, the fractography was classified as brittle and transgranular fracture and the interdendrites played a major role in the failure of as-weld Alloy ENiCrFe-7, and the fractography was ductility fracture for the heat treatment one after 615℃/48h.`
In Silico Molecular Docking Approach Against Enzymes Causing Alzheimer’s Disease Using Borassus Flabellifer Linn
Authors: Abraham Jason Tom , Maharifa H. Noorul Samsoon , Hemalatha S
Published: August 2021

Alzheimer’s disease is a life-threatening neurodegenerative disorder. About 50 million people across the globe are affected by this disease. At final stages, this disease causes patients to lose cognitive ability, memory and brain cells to the point of being totally depend on other individuals for livelihood. The incidence of this disease is increasing across the world in the recent years, making the need of a better drug an urgency. Existing drugs show various side-effects and natural sources of medicinal drugs are being explored. In this study, we explore the activity of natural compounds isolated through GCMS analysis from the haustoria of palmyra palm against two major Alzheimer’s disease-causing enzymes, β-amyloid and Acetylcholinesterase. The binding affinity of these compounds against the target proteins and their pharmacokinetic properties were checked. Among the 37 compounds docked, 5 compounds showed good binding affinity and pharmacokinetic properties. These natural compounds showed a potential as a drug against Alzheimer’s disease. Further research is needed to study the synergistic activity of the compounds in live cells.
Omitting Surgery In Esophageal Cancer Patients With Complete Response After Neoadjuvant Chemoradiotherapy: A Systematic Review And Meta-Analysis
Authors: Park Jaehyeon , Yea Ji woon , Park Jaewon
Published: August 2021

Neoadjuvant chemoradiotherapy (nCRT) followed by surgery is a standard treatment modality for locally advanced esophageal cancer. However, patients who achieve clinical complete response (cCR) after nCRT have been reported to have better prognosis. Further, the role of surgery in these patients is controversial. Thus, this meta-analysis aimed to evaluate whether surgery is still useful in patients with cCR after nCRT. We systematically reviewed the MEDLINE, PubMed, Embase, Cochrane library, and Scopus databases for studies on surgical efficacy in complete responders after concurrent chemoradiotherapy for esophageal cancer. The publication date was set to January 1, 2010–January 31, 2020. The hazard ratio (HR) and risk ratio was used to compare 2-year overall survival (OS), disease-free survival (DFS), incidence of locoregional failure, distant metastasis and treatment mortality between the nCRT and the nCRT plus surgery groups. Six articles involving 609 patients were included. There was a significant benefit of nCRT for OS (HR = 0.80, 95% confidence interval [CI] = 0.64–0.99, p = 0.04), but not for DFS (HR = 1.19, 95% CI = 0.41–3.46, p = 0.75). The nCRT group tended to have lower mortality than the nCRT plus surgery group (risk ratio = 0.15, 95% CI = 0.02–1.18, p = 0.07). Omitting surgery provides better OS in complete responders after nCRT. Adding surgery could increase the morbidity and mortality and decrease the quality of life. Thus, nCRT alone could be a feasible approach for patients with cCR.
Study on the Mechanism of Lupenone for Treating type 2 Diabetes by Integrating Pharmacological Evaluation and Network Pharmacology
Authors: Xu Feng , Wu Hongmei , Wang Yuanmin , Yang Ye , Wang Xiangpei
Published: August 2021

Background: Lupenone (LUP) is the active ingredient of Rhizoma Musae, which has good anti-diabetes effects, but the underlying mechanism is unclear. In this study, animal experiments combined with network pharmacology were used to explore the mechanism of LUP for treating diabetes. Methods: Type 2 diabetic rats with insulin resistance (IR) were induced by a high-fat diet and streptozotocin. the fasting blood glucose (FBG), index of oxidative stress, blood lipids, and IR-related targets in skeletal muscle and adipose were detected. a network pharmacology-based strategy was also adopted to clarify the mechanism of LUP for treating diabetes by improving IR. Results: LUP decreased the FBG levels and synthesis of glycogen, improved oxidative stress and lipid metabolism disorders, and increased the gene and protein expression of insulin receptor, insulin receptor substrate (IRS)-1, IRS-2, glucose transporter type 4 (GLUT-4) in skeletal muscle and peroxisome proliferator-activated receptor γ, IRS-1, IRS-2, GLUT-4 in adipose. Network pharmacology analysis revealed that LUP improves IR by multiple targets (like INS, TP53, TNF, SRC and ESR1) and signal pathways. Conclusion: These results suggested that the mechanism of LUP for treating diabetes is closely related to improving IR. LUP has the potential to develop as a new drug for the treatment of type 2 diabetes.
Tailoring plasmon excitations in α − T3 armchair nanoribbons
Authors: Iurov Andrii , Zhemchuzhna Liubov , Gumbs Godfrey , Huang Danhong , Fekete Paula , Anwar Farhana , Dahal Dipendra , Weekes Nicholas
Published: August 2021

We have calculated and investigated the electronic states, dynamical polarization function and the plasmon excitations for α − T3 nanoribbons with armchair-edge termination. The obtained plasmon dispersions are found to depend significantly on the number of atomic rows across the ribbon and the energy gap which is also determined by the nanoribbon geometry. The bandgap appears to have the strongest effect on both the plasmon dispersions and their Landau damping. We have determined the conditions when relative hopping parameter α of an α − T3 lattice has a strong effect on the plasmons which makes our material distinguished from graphene nanoribbons. Our results for the electronic and collective properties of α − T3 nanoribbons are expected to find numerous applications in the development of the next-generation electronic, nano-optical and plasmonic devices.
Gene cloning, functional expression and characterization of a novel GH46 chitosanase from Streptomyces avermitilis (SaCsn46A)
Authors: Guo Jing , Wang Yi , Gao Wenjun , Wang Xinrou , Gao Xin , Man Zaiwei , Cai Zhiqiang , Qing Qing
Published: August 2021

A novel glycoside hydrolase (GH) family 46 chitosanase (SaCsn46A) from Streptomyces avermitilis was cloned and functionally expressed in Escherichia coli Rosetta (DE3) strains. SaCsn46A consists of 271 amino acids, which includes a 34-amino acids signal peptide. The protein sequence of SaCsn46A shows maximum identity (83.5%) to chitosanase from Streptomyces sp. SirexAA-E. Then the mature enzyme was purified to homogeneity through Ni-chelating affinity chromatography with a recovery yield of 78% and the molecular mass of purified enzyme was estimated to be 29 kDa by SDS-PAGE. The recombinant enzyme possessed a temperature optimum of 45 oC and a pH optimum of 6.2, and it was stable at pH ranging from 4.0 to 9.0 and below 30 oC. The Km and Vmax values of this enzyme were 1.32 mg∙mL− 1, 526.32 µM∙mg− 1∙min− 1, respectively (chitosan as substrate). The enzyme activity can be enhanced by Mg2+ and especially Mn2+, which could enhance the activity about 3.62-fold at a 3 mM concentration. The enzyme can hydrolyze a variety of polysaccharides which linked by β-1,4-glycosidic bonds such as chitin, xylan and cellulose, but it could not hydrolyze polysaccharides linked by α-1,4-glycosidic bonds. The results of thin layer chromatography and HPLC showed that the enzyme exhibited an endo-type cleavage pattern and could hydrolyze chitosan to glucosamine (GlcN) and (GlcN)2. This study demonstrated that SaCsn46A is a promising enzyme to produce glucosamine and chitooligosaccharides (COS) from chitosan.
Design of Hybrid Narrow-Band Plasmonic Absorber Based on Chalcogenide Phase Change Material in the Infrared Spectrum
Authors: Oliveira Israel Alves , Souza I. L. Gomes , Rodriguez-Esqu V. F.
Published: August 2021

Structures absorbing electromagnetic waves in the infrared spectral region are important optical components in key areas such as biosensors, infrared images and thermal emitters, and require special attention from reconfigurable devices. We propose a three-dimensional metal-dielectric plasmonic absorber with a layer of PCM's (Phase Change Materials). The phase shift effects of PCMs are analyzed, and it is possible to obtain a displacement control in the resonant absorption peaks between the amorphous and crystalline states using the Lorentz-Lorenz relation. Aided in this empirical relation, we analyzed the absorption shift in the intermediate phases between them. The geometric parameters of the structure with the pcm material layer in the semi-crystalline state were optimized to present strong absorption for normal incidence. The effects of the oblique incidence for the TM and TE polarization modes were also analyzed. Our results demonstrate that PCMs have great potential for reconfigurable nanophotonic devices.
LMWF5A Demonstrates an Anti-Inflammatory Mode of Action and Similar Drug Targets to Dexamethasone in Activated PBMC
Authors: Frederick Elizabeth D. , Hausburg Melissa A. , Thomas Gregory W. , Bar-Or David
Published: August 2021

The low molecular weight fraction of human serum albumin (LMWF5A) has proven immunomodulatory activity via its effects on multiple inflammatory mediators and transcription factors. This biologic drug is currently being evaluated for the treatment of conditions characterized by hyperactive or persistent immune responses. To gain further insight into the mechanism of action of LMWF5A, an unbiased investigation of its effects on activated immune cells was performed. Peripheral blood mononuclear cells (PBMC) were treated with vehicle control or LMWF5A and stimulated with lipopolysaccharide (LPS), LPS/interferon γ, or interleukin (IL)-4/IL-13 for 24h. Differential gene expression analysis by RNAseq was performed to determine transcriptional changes due to LMWF5A treatment in each stimulation condition. Ingenuity Pathway Analysis software was employed to reveal overall biological trends observed in the RNAseq datasets and to identify compounds with comparable or contrasting activities to LMWF5A. Analysis of each RNA dataset revealed broad anti-inflammatory and pro-resolving activities for LMWF5A, with predicted inhibition of key pro-inflammatory mediators and functions as well as activation of some anti-inflammatory mediators. Upstream regulator analysis confirmed these activities and identified the corticosteroid dexamethasone as the most significantly similar regulator. Further comparison of LMWF5A and dexamethasone revealed similar, but not identical, targets and directional regulation. This study supports our current knowledge on the mode of action of LMWF5A and provides new hypotheses for future investigations. Due to its analogous biological effects with dexamethasone and known safety profile, LMWF5A may be used to treat conditions that are supported for dexamethasone with fewer or less harmful side effects.
Carbon Black Nanoparticles Exposure Induces Intestinal Flora Dysbiosis and Consequent Activation of Gut-liver Axis Leading to Liver Lipid Accumulation in Zebrafish
Authors: Liu Qingqing , Wang Bing , Wang Shengchen , Jing Hongyuan , Xu Shiwen
Published: August 2021

BackgroundCarbon black nanoparticles (CBNPs) are a major carbonaceous nanomaterial, which have been widely left in the environment. The integrity of the gut-liver axis function is critical to the survival of animals. Therefore, we studied the effects of three concentrations of CBNPs (50, 100, 200 mg/L) on zebrafish intestines, liver and intestinal flora. ResultsThe results showed that CBNPs exposure could reduce the diversity of intestinal flora, change the structure of core microbial populations, enhance the permeability of the intestinal mucosal barrier, and cause changes in genes related to tight junctions in intestinal tissues. The H&E staining and Oil red O staining showed that CBNPs exposure would lead to vacuolar degeneration and lipid accumulation in zebrafish liver. Further detection of glycolipid metabolism related genes showed that CBNPs exposure induced the up-regulation of glycolysis related genes PFKFB3, LDHA, and LEPr, reduces the expression of glycogen synthase kinase GSK-3b, and increases lipid transport and production related genes PPAR-α, PPAR-γ, LIPC, apoa4, Fabp2 and Fabp11 expression. ConclusionsIn brief, our data demonstrated that CBNPs exposure induced intestinal microflora disturbance in zebrafish can lead to liver lipid accumulation.
Experimental Validation and Numerical Simulation of Flexible and Micro-scale Roll Gap Control Technology
Authors: Yang Tingsong , Chen Qifa , Feng Yanfeng , Hai Yang , Du Fengshan
Published: August 2021

To obtain a better ability of strip flatness control, this paper proposes a new flexible and micro-scale roll gap control technology. According to the principle of roll profile electromagnetic control technology (RPECT), a new electromagnetic control rolling mill with the function of roll profile control and large diameter ratio rolling is designed and built. To analyze the flatness control ability of this mill, a comprehensive finite element model (FEM) is established and verified, which includes a FEM for predicting the electromagnetic control roll profile and a FEM of rolling process. The simulation results show that the crown control ability of RPECT is stronger than the quadratic crown control ability, and the effect of tension on the roll gap shape crown is small. The results in the indentation experiment and the rolling experiment show that increasing the roll crown of electromagnetic control roll can adjust the strip shape form edge wave to non-wave, and middle wave. The feasibility of using RPECT to adjust the roll gap shape has been verified, and the roll gap control goal of uniform transverse size distribution can be achieved.
The Unexpected Relationship Between Extreme Shear Events and AMO
Authors: qiu weiteng , yan xiaodong
Published: August 2021

The vertical shear–the change in wind speed with height-of horizontal winds is a serious threat to the safety of aircraft. Yet their global distribution is not fully understood. We creatively used a precise method to calculate different types of vertical shear at four isobaric surfaces during the period of 1979~2018. The occurrence of severe shear events has increased by 19%, and they mostly occur over the equatorial ocean and within the mid-high latitude zone of the Northern hemisphere, while light shear event occurrence has been reduced by 21%. Variations of severe shear are modulated by the Atlantic Multidecadal Oscillation (AMO), which affects the frequency of shear events by influencing the intertropical convergence zone (ITCZ). Our study implies that severe shear events are regulated by internal climate variability.
Should the susceptibility of cervid to coronaviruses be a matter of concern?
Authors: Lopes Luciano Rodrigo
Published: August 2021

The susceptibility of the white-tailed deer (Odocoileus virginianus) to SARS-CoV-2 has highlighted cervids as a new coronavirus reservoir. Cervids are known hosts for other coronaviruses (such as bovine-like coronavirus) and can harbour several pathogens that cause serious diseases in humans. Moreover, herds of cervids are largely distributed among wildlife and are in close contact with humans, who often hunt or rear these animals The increased incidence of severe acute coronavirus 2 (SARS-CoV-2) infections, especially in American countries, which serve as habitats for many cervids, including the white-tailed deer and other closely related species, can favour the transmission of coronaviruses from humans to wild animals. In this context, this letter briefly discusses some points that underscore the occurrence of SARS-CoV-2 infections in cervids as a matter of concern.
Machine learning and deep learning techniques to support the clinical diagnosis of arboviral diseases: A systematic review
Authors: Neto Sebastião Rogério da Silva , Oliveira Thomás Tabosa , Teixeira Igor Vitor , de Oliveira Samuel Benjamin Aguiar , Sampaio Vanderson Souza , Lynn Theo , Endo Patricia Takako
Published: August 2021

Background: NTDs primarily affect the poorest populations, often living in remote, rural areas, urban slums or conflict zones. Arboviruses are a significant NTD category spread by mosquitoes. Dengue, Chikungunya, and Zika are three arboviruses that affect a large proportion of the population in Latin and South America. The clinical diagnosis of these arboviral diseases is a difficult task due to the concurrent circulation of several arboviruses which present similar symptoms, inaccurate serologic tests resulting from cross-reaction and co-infection with other arboviruses. Objective: The goal of this paper is to present evidence on the state of the art of studies investigating the automatic classification of arboviral diseases to support clinical diagnosis based on ML and DL models. Method: We carried out a SLR in which Google Scholar was searched to identify key papers on the topic. From an initial 963 records (956 from string-based search and 7 from single backward snowballing technique), only 15 relevant papers were identified. Results: Results show that current research is focused on the binary classification of Dengue, primarily using Tree based ML algorithms and only one paper was identified using DL. Five papers presented solutions for multi-class problems, covering Dengue (and its levels) and Chikungunya. No papers were identified that investigated models to differentiate between Dengue, Chikungunya, and Zika. Conclusions: The use of an efficient clinical decision support system for arboviral diseases can improve the quality of the entire clinical process, thus increasing the accuracy of the diagnosis and the associated treatment. It should help physicians in their decision-making process and, consequently, improve the use of resources and the patient's quality of life.
Nucleic Acid Sequence Composition of the Oxford – AstraZeneca Vaccine ChAdOx1 nCoV-19 (AZD1222, Vaxzevria)
Authors: Radukic Marco T. , Le Dinh To , Müller Kristian M.
Published: August 2021

The vaccine ChAdOx1 nCoV-19 has been widely used, but its purity has been disputed because of rare side effects. We used Nanopore sequencing to assess the sequence and genetic purity of a vaccine dose. As we were lacking a reference sequence for the antigen cassette, we provide the obtained annotated sequence of the full vector to aid further studies on this topic. Our sample adhered to the published data, was highly pure (>99.97%), and no copy of the E1 gene as a predictor on replication-competent escape mutants was found.
Disentangling the effect of regional SST bias on the double-ITCZ problem
Authors: Lee Jiheun , Kang Sarah M. , Kim Hanjun , Xiang Baoqiang
Published: August 2021

This study investigates the causes of the double intertropical convergence zone (ITCZ) bias by disentangling the individual contribution of regional sea surface temperature (SST) biases. We show that a previously suggested Southern Ocean warm bias effect in displacing the zonal-mean ITCZ southward is diminished by the southern midlatitude cold bias effect. The northern extratropical cold bias turns out to be most responsible for a southward-displaced zonal-mean precipitation, but the zonal-mean diagnostics poorly represent the spatial pattern of the tropical Pacific response. Examination of longitude-latitude structure indicates that the overall spatial pattern of tropical precipitation bias is largely shaped by the local SST bias. The southeastern tropical Pacific wet bias is driven by warm bias along the west coast of South America with negligible influence from the Southern Ocean warm bias. While our model experiments are idealized with ocean dynamics being absent, the results shed light on where preferential foci should be applied in model development to improve the certain features of tropical precipitation bias.
Quantifying renin-angiotensin-system alterations in COVID-19
Authors: Pucci Fabrizio , Annoni Filippo , Santos Robson Augusto Souza dos , Taccone Fabio Silvio , Rooman Marianne
Published: August 2021

The renin-angiotensin system (RAS) plays a pivotal role in a wide series of physiological processes. One of its key components, the angiotensin-converting enzyme 2, has been identified as the entry point of the SARS-CoV-2 virus into the host cells, so many studies have been devoted to study RAS dysregulation in COVID-19. Here we discuss the alterations of the regulatory RAS axes due to SARS-CoV-2 infection on the basis of a series of recent clinical and experimental analyzes, which, for example, quantify the levels and activity of RAS components, in order to disentangle the links between the impaired RAS functioning and the pathophysiological characteristics of COVID-19. Finally, we discussed the effects of some RAS-targeting drugs, and how they could potentially contribute to restore the normal RAS functionality and minimize COVID-19 severity.
Employee’s state of health as a reason for termination of an employment contract at the initiative of the employer
Authors: Олена Олександрівна Конопельцева
Published: August 2021

The grounds on which the employer is allowed to terminate the employment contract with the employee are considered if the employee's inconsistency with the position or job is established. It is emphasized that dismissal of an employee is allowed in case of a discrepancy due to a state of health, which hinders the continuation of this work, if it is impossible to transfer him to an easier job due to the absence of a vacant job or refusal to transfer. A characteristic feature of dismissing an employee due to poor health is the lack of guilt. The inability of the employee to perform his or her work duties is linked to the state of health and does not depend on his will and desire, and therefore cannot be blamed on him. The article proves that temporary disability cannot be considered as a reason to dismiss a worker.According to the medical report, the owner or his authorized body must transfer such persons with their consent to such work temporarily or without a time limit. Such transfer of an employee is possible under the conditions on which both medical and legal basis can be.In the case of refusal of the employee to transfer or absence at the enterprise of work that he could perform without harm to his health, the owner or his authorized body may raise the issue of his dismissal in due course due to the found inconsistency of the occupied position or performed work due to a state of health that impedes the continuation of this work (paragraph 2 of Article 40 of the Labor Code of Ukraine). Such dismissal shall be allowed in the exceptional cases where the owner or his authorized body really does not have the opportunity to transfer the employee upon his or her consent to another job according to a medical report.
Polysemia as a defect of criminal procedure law
Authors: Elena Leiba
Published: August 2021

The article is devoted to the identification of characteristic features of legislative defects caused by regulatory legal acts (or within legislative acts) of terminological interpretations that are ambiguous. Polysemy quite often has a negative impact on the universal conceptual-categorical apparatus. Attention is drawn to the fact that the homogeneity of the subject matter of the legal regulation requires the maximum terminological clarity, since the context of the individual legal relations is not in itself sufficiently pronounced to provide a clear delineation of the meaning of the ambiguous term. The manifestations of normative polysemy only reduce the clarity of the law and create difficulties in law enforcement, including in the field of criminal justice. The manifestation of polysemy in criminal procedural law is considered on the example of the ambiguous legal term "reconciliation", the definition of legal meaning of which is determined only by the context of its use. In addition, the study draws attention to the fact that in the criminal procedural legislation there are cases where the problem of polysemy is not solved by taking into account the contextual meaning, and the use of means of interpreting the text of the law does not provide a clear answer. This situation is illustrated by an example of the use by the legislator of the identical terminological designation "trial" both for the name of the stage of proceedings in the court of first instance, and for the name of its separate (second) stage, which involves the examination of evidence. Suggestions are made to eliminate and overcome the described legislative defects.
To the question of recognizing the ecosystem approach as a quintessential principle of environmental law
Authors: Євгеній Павлович Суєтнов
Published: August 2021

On the grounds of the comprehensive analysis of the views of scientists, the article explores the principle of the ecosystem approach in environmental law.It is substantiated that in the modern environmental legal doctrine there is no clear and unambiguous understanding of the essence of this principle and its place among other principles of environmental law, because scientists, considering this principle an independent principle, simultaneously recognize it as a sign of rational use of natural resources, identify it with the complex and sustainable use of natural resources or generally see it in the vast majority of principles of environmental law.Given the novelty, extreme intricacy and unconventionality of the principle of the ecosystem approach, it is proposed to consider it as a quintessential principle of environmental law, which, found on the objective conditions of nature’s existence, denoted by the interdependence and interconditionality of all natural processes and phenomena, “permeates” all principles of environmental law and at the same time serves as their backbone, the essence.The article concludes by emphasizing the need to rethink environmental law and its principles on the basis of the ecosystem approach.
Detection of lane line based on Robert operator
Authors: Wei Yangzhe , Xu Miao
Published: August 2021

As autonomous driving technology becomes more and more popular, its safety is also attracting attention. Regarding the automatic driving of vehicles, the detection of road markings is particularly important. This paper improves the lane edge detection part of the Hough transform lane line detection method. Because the traditional Canny operator edge detection method is good for image processing, but the detection time is long, this paper replaces the Canny algorithm with the Robert operator edge detection method. The sub-edge detection method can improve the detection speed of lane line extraction. In MATLAB, by using multiple edge detection operators to perform edge detection on the same image 100 times, and taking the average of the detection time, it is found that the Robert operator takes a shorter time in the detection process than the Canny operator; Then the Robert operator and Canny operator are respectively fused into the Hough transform lane line detection. After 100 times, the same image is detected, and the running time is statistically averaged for comparison and analysis. The Robert operator is better than the Canny operator. The time taken is reduced by 0.15191 s. The simulation results show that the integration of Robert operator in Hough transform lane line detection improves the real-time performance of lane detection.
Gear compound fault detection method based on improved multiscale permutation entropy and local mean decomposition
Authors: Chen Yongqi , Chen Yang , Dai Qinge
Published: August 2021

The traditional multiscale entropy algorithm shows inconsistency because some points are ignored when the signal is coarsened. To solve this problem, this paper proposes an improved multiscale permutation entropy (IMSPE). Firstly, the fault signal is decomposed into several product functions (PF) by local mean decomposition (LMD). Secondly, IMSPE is proposed to extract fault features of product functions. IMSPE integrates the information of multiple coarse sequences and solves problems of entropy inconsistency. Finally, the proposed method based on LMD and IMSPE is applied into gear fault diagnosis system. The experiment shows the proposed method can distinguish different gear fault types with a higher accuracy than traditional methods.
Research progress of cavity-based acoustic energy harvester
Authors: Li Zhipeng , Zou Huajie , Li Jinghao , Chen Hejuan
Published: August 2021

The acoustic energy collector uses the cavity acoustic mode to capture the acoustic signal in a certain frequency range at the mouth of the cavity, achieves fluid-solid coupling and amplifies the acoustic vibration excitation, and then through piezoelectric, magnetoelectric and friction power generation mechanisms, the acoustic energy is finally converted into electrical energy. The overview of the research progress of cavity-based acoustic energy harvesters has found that acoustic energy harvesters are usually composed of resonant cavity, diaphragm, and transducer materials, and the resonant cavity is the key to the design of acoustic energy harvester. Analyze the influence of cavity structure on sound pressure amplification to provide reference for the research and application of acoustic energy harvester. The piezoelectric type is the main energy conversion method, the magnetoelectric type is the auxiliary, and the friction power generation and the acoustic crystal resonance power generation have also become a new research direction, because of the widest application range of hybrid power generation, it has become a future development trend.
Simulation of ecohydrological processes influencing water supplies in the Tuul River watershed of Mongolia
Authors: Norvanchig Javzansuren , Randhir Timothy O.
Published: August 2021

Achieving sufficient water supplies for multiple uses in the watershed is a major public policy issue. Understanding the current ecohydrologic processes is essential to assess potential impacts on hydrologic regimes. The Tuul River (TR) watershed faces a cold, continental climate with water supply variability. This study aims to simulate watershed processes in the TR watershed and subbasins and analyze the influences of those processes on water resources. Watershed hydrologic processes and their impact on the water resources are modeled using the Soil Water Assessment Tool (SWAT). Calibration and validation were conducted using R2, PBIAS, RSR, and NSE to assess the effectiveness of the SWAT model to replicate annual, monthly streamflow values. The spatial and temporal variations in watershed processes are critical for water resource decisions. With increasing uncertainty and scarcity in water resources, simulation modeling is a valuable tool in watershed management in regions with water scarcity.
Ansiedade e depressão no contexto da pandemia de COVID-19
Authors: Daldegan Natassia , Silveira Soares Rayane Aparecida , Morais Farias Jonathas
Published: August 2021

Este artigo se trata de um levantamento documental a fim de compreender as demandas da população que procurou o serviço de atendimento do Centro de Práticas Psicológicas (CEPRAPSI) da Universidade Federal de Rondonópolis (UFR) no ano de 2020 sob a justificativa de apresentar queixas relativas ao isolamento social ou qualquer outro sintoma que julgasse estar associado à pandemia de COVID-19. O mesmo decorre da prática de um projeto de extensão do curso de Psicologia da mesma universidade. O estudo se debruçou em caracterizar os documentos gerados pela ficha de inscrição de 63 pessoas, cuja análise se deu pelo levantamento das porcentagens de incidência das respostas encontradas bem como pela avaliação das queixas apresentadas. As queixas revelaram que o contexto pandêmico agrava os sintomas de depressão e ansiedade, produzindo sofrimento psíquico.

Palavras-chave: psicoterapia online; serviço-escola; tratamento psicológico; distanciamento social;
AÇÕES EXTENSIONISTAS EM MEIO A PANDEMIA
Authors: Matheus Batista Medeiros Ítalo , Pereira de Araújo Dantas Gabriela , Jade Alves de Carvalho Vitória , Luiz de Melo Sousa André , Bezerra Brasil Amíria
Published: August 2021

Apesar da ampla veiculação de notícias e recomendações acerca da pandemia do novo Coronavírus - e da doença COVID-19 - o EMAU Maré e o grupo ATHIS da UFRN identificaram que a linguagem e a representação dessas eram muito técnicas, e viram a necessidade de produzir um material de mais fácil compreensão direcionado para as comunidades populares. O conteúdo audiovisual também partiu da urgência de repensar a extensão universitária em um contexto de distanciamento social, visualizando a internet e as redes sociais como um instrumento para que os grupos extensionistas pudessem fomentar a discussão da saúde nos assentamentos populares. Assim, neste artigo será discutida a necessidade de criar material que corresponda à realidade dessas pessoas e serão apresentados a metodologia, o conteúdo e o público-alvo da cartilha e dos vídeos produzidos pelo grupo.

Palavras-chave: extensão; Covid-19; assentamentos populares; linguagem acessível; cartilha informativa.
Understanding Informal Communication Environment Effect on Social Inclusion
Authors: Genel Zeynep
Published: August 2021

The Syrian Civil War forced the citizen population to flee to neighboring countries. Turkey host one of the most densely populated Syrian asylum seekers since 2011. Therefore, social adaption, social cohesion and social integration became the most discussed topics of social studies. Most studies conducted to understand the advantages and disadvantages between two societies in social adaptation. Language is the dominant barrier to social and cultural integration. But some of the newest studies on understanding Syrian population issues shown that communication is the second challenge for the Syrian asylum seekers living in Turkey. Authorities, civic initiatives planned strategic communication facilities to access the Syrian asylum - seekers' adaptation process. So many of these implied by the formal communication sources or channels. This paper aims to direct researchers consider to the importance of informal communication for understanding a close society's communication tendencies and offers to integrate informal communication layer for providing more success.

In this perspective, the paper refer the informal communication preferences of Syrian asylum-seekers in Turkey and observe the role of these preferences. So, a qualitative study applied with asylum-seekers in Turkey. As a result, the findings show that key opinion leaders, multi-lingual neighbors and social media are among the effective informal communication channels. This paper aims to start a discussion about the gap of informal communication and it may be useful for policy makers to think about this aspect of communication.
Sulfated Tin Oxide: A Convenient Heterogeneous Catalyst for the Synthesis of 4-Arylmethylidene-3-Substituted-Isoxazol-5(4H)-Ones
Authors: Kaminwar Nitishkumar S. , Tekale Sunil U. , Nakkalwar Srinivas L. , Pawar Rajendra P.
Published: August 2021

Synthesis of isoxazole structural heterocyclic compounds is important due to their wide range
of biological activities. In the present article, we report a convenient and easy method for the synthesis of
4-arylmethylidene-3-substituted-isoxazol-5(4H)-ones by the one-pot three-component reaction of aldehydes,
β-keto ester, and hydroxylamine hydrochloride catalyzed by sulfated tin oxide as a heterogeneous
catalyst.
Nawyki żywieniowe u pacjentów z cukrzycą typu 2
Authors:   Państwowa Uczelnia Zawodowa we Włocławku, Antczak-Komoterska Anna , Gołębiewska Malwina ,   MZOZ Przychodnia numer 6 Poradnia Dziecięca ul. Kaliska 104a we Włocławku
Published: August 2021

Admission. Diabetes mellitus is a chronic disease caused by a disturbance in insulin secretion. Diet is a very important element in the treatment of diabetes. It is a prerequisite for maintaining the proper concentration of glucose and fats (lipids) in the blood and optimal blood pressure. A well-chosen diet reduces the risk of diabetes complications and reduces the risk of vascular diseases. An appropriate nutrition model also plays an important role in the prevention and treatment of chronic diabetes complications (microangiopathy, retinopathy and diabetic nephropathy). Aim. The aim of this study was to evaluate the influence of eating habits on patients with type 2 diabetes. Material and methods. The paper uses the method of a diagnostic survey. The research techniques that were used for the purposes of the research process were: surveying and estimation scale technique. The tool that was used in the study was the proprietary questionnaire of the self-survey. Results. The research results show that the patients have good and bad eating habits. Positive behaviors relate to the number of meals and the way of cook-ing. Most women indicated that they eat 4-5 meals a day – 39,0%. The negative ones include snacking between meals (most women indicated that they some-times eat between meals – 58,0%, the least that not – 8,0%), high consumption of sweets (most women indicated that they eat sweets several times a day – 23,0%, the least indicated that 3-4 times a week – 13,0%), and lower frequency of selecting fish compared to healthy women. Conclusions. It turns out that the level of knowledge about positive eating hab-its is average. Therefore, the aim of preventive actions is to make the public aware of the importance of a proper diet, the number of meals taken and the way of their preparation.
Analiza częstości występowania oraz czynników wpływających na powstanie wad postawy u dzieci w wieku szkolnym
Authors:   Państwowa Uczelnia Zawodowa we Włocławku, Kochman Dorota , Studzińska Aneta ,   Centrum Diagnostyczno-Lecznicze Barska we Włocławku
Published: August 2021

Introduction. Faulty posture is define as the syndrome of bad posture that we characterize as minimal, individual anomalies upon proper poise which are potentially curable with professional passive and active exercises. An im-portant function at develop posture anomalies has factors which induce to take improper silhouette. To the above factors mainly belong: bad posture while relaxation, wrong place to study or hefting overloaded packs. Aim. Depiction of common problem among children at school age which is exposure of faulty posture and specification of factors which produce faulty posture. Material and methods. In the thesis was used method of evaluation and diag-nostic survey method. With the object of execution the questionnaire surveys applied an anonymous and authorial questionnaire at the same time. A hundred of children at 11-14 age entered the survey. Based on data, computed BMI rate and the anthropometric parameters were evaluated according to centile grid. Results. A hundred of children entered the research (49% boys, 51% girls). 24% of children had diagnose of faulty posture namely 16 girls and 8 boys. Fallen arches was detected at 11 children, it is about 46% of people with bad posture, whereas none of children had knees valgus (0%). 38% of children who are active less than hour per day were diagnosed with faulty posture, whereas group of people with 1-2 hours daily physical activity had only 16,1% of chil-dren with faulty posture. On the other hand with students who spare over two hours on activity daily were not any fault. 87,5% of respondents with wrong BMI rate level suffer from bad posture. Children (66%), who do not respect right rules of carrying pack have diagnosed faulty posture. Conclusion. Every fourth child at research group has bad posture. The com-mon type of faulty posture is fallen arches, but the rarest is knee valgus. Low level of physical activity and wrong way of carrying pack significantly contrib-ute to develop faulty posture among school age children. Furthermore inade-quate result of BMI also has negative impact on body posture of child.
Opieka pielęgniarska nad pacjentką w przebiegu choroby Alzheimera z wykorzystaniem ICNP®
Authors:   Państwowa Uczelnia Zawodowa we Włocławku, Krajewska Karolina
Published: August 2021

Introduction. Alzheimer's disease (AD – Alzheimer Disease) is an incurable neurodegenerative disease. The main source of memory discomfort is destruc-tion. With age, irresistibly falling ill with it. Risk factors for the development of Alzheimer's disease are primarily: diabetes, female gender, hypertension and the lack of a control field. It is estimated that in Poland Alzheimer's disease affects about 200,000 people. According to statistics, 60% of all forms of de-mentia are AD. Aim of the study. The aim of the study is to present the activities that should be performed by a nurse caring for a patient with diagnosed Alzheimer's dis-ease. Case study. A 75-year-old patient admitted to the internal medicine ward, she has communication, content swallowing and spatial orientation disorders. It requires constant assistance in the performance of everyday activities. He complains of urinary and faecal incontinence. Conclusion. Thanks to the holistic approach to the patient, it is possible to ensure her correctness and the approach of the patient and her family.
Alergeny ziół kulinarnych i warzyw ważne dla pielęgniarki lub dietetyczki
Authors:   Państwowa Uczelnia Zawodowa we Włocławku, Buczyłko Krzysztof
Published: August 2021

Introduction. New allergenic sources causing the oral allergy syndrome and other allergic diseases have been reported. Overview. The spices, vegetables and some culinary herbs allergenic mole-cules have been identified and presented with their cross-reactivity possibili-ties. Some of the molecules generally considered not to be at risk for severe reactions have been demonstrated to pose a threat for inducing generalized reactions. Conclusions. Molecular allergology basic rules are useful for nurses and dieti-tians as well.
Wybrane aspekty opieki pielęgniarskiej realizowanej wobec pacjenta po przebytym udarze niedokrwiennym mózgu
Authors:   Państwowa Uczelnia Zawodowa we Włocławku, Szklarczyk Kasandra , Sztandarowicz Wiktoria ,   Państwowa Uczelnia Zawodowa we Włocławku, Szyjkowska Emilia ,   Państwowa Uczelnia Zawodowa we Włocławku, Sak Paulina ,   Państwowa Uczelnia Zawodowa we Włocławku
Published: August 2021

Introduction. Stroke is a clinical syndrome in which focal or global brain dysfunction suddenly occurs. Despite the progress in diagnostics and treatment options that has been noticeable in recent years, stroke is the third most common cause of death in industrialized countries. In Poland, there are 60,000 people after a stroke every year, half of them die during the first year. Stroke patients often become dependent and needs help from other people. Aim. The aim of this study is to analyze selected aspects of nursing care provided to a patient after an ischemic stroke. Material and methods. Analysis of available literature related to issue of stroke and nursing care in patients after stroke as well as mapping medical diagnosis and interventions using the INCP ® dictionary. Results. Using the ICNP classification allows to show the patient's state of health after a stroke and plan nursing care based on uniform professional terminology.
Edukacja dla bezpieczeństwa w zakresie udzielania pierwszej pomocy dla uczniów klasy VIII szkoły podstawowej
Authors:   Szkoła Podstawowa nr 100 im. płk. Frańcesco Nullo w Warszawie, Mikulski Michał
Published: August 2021

Safety education in the 8th grade of primary school in the field of first aid is an innova­tive and important subject for our society. Adolescent pupils acquire knowledge, de­velop skills and learn to collaborate in a team. While conducting educational classes in the field of first aid it is important to remember to adjust the level of teaching to the needs and abilities of the students. The aim of practical classes should always be to consolidate the protocols of first aid treatment. The subject of participant observation were practical exercises for pupils from the 8th grade of primary school. The results of the classes showed the pupils’ involvement and skill development as well as effective­ness in the field of first aid.
Ćwiczenia kompleksowe na lotnisku jako element doskonalenia zawodowego strażaków Państwowej Straży Pożarnej
Authors:   Akademia WSB, Musiał Artur
Published: August 2021

This article is an attempt to analyze the perception of the subject of airport rescue through the prism of tasks performed by the State Fire Service firefighters, i.e. an auxiliary external service. The reflections of the author are based on his earlier research on the usefulness of the participation of State Fire Service firefighters in comprehensive (full-scale) exercises at the airport in the process of professional development.
Space Syntax-able Attributions for Safety Consideration of Heritage Area
Authors: Kezuwani Noor Kamilah , Said Shahrul Yani
Published: August 2021

Understanding crime has been in focus for a few decades. Significant research has begun to understand the relationship between spatial configuration and crime occurrence, which related back to human behaviour. In recent year, space syntax has been used as a method to analyse space and its spatial properties. Urban design researchers have employed the space syntax technique to analyse the geographic distribution of crime due to spatial and socio-demographic factors that could influence crime patterns. This paper describes how space syntax could be used to assess crime possibility in heritage areas, and the result supports the hypothesis.
Keywords: Urban planning, Crime prevention theory, Space syntax, Spatial configuration
eISSN: 2398-4287© 2021. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v6iSI4.2903
Constructivist Digital Game-Based Learning Courseware for Slow Learners with Numeracy Difficulties
Authors: Harikrishnan Hemanathan , Abd Halim Noor Dayana , Harun Jamalludin , Arjunan Shalini
Published: August 2021

DGBL is a suitable tool for teaching slow learners, as it allows them to engage actively and practice DGBL Courseware as a learning tool. This paper aims to identify slow learners' difficulties in Mathematics. The develop a DGBL Courseware incorporating Constructivism principles and Engagement Game-Based Elements by Prensky. The research method focuses on following stages: requirement analysis, design and development, including alpha testing by validation from experts, and beta testing, which is user acceptance test to support the efficiency and effectiveness of the Courseware for further improvement.
Keywords: Constructivism, Digital Game-Based Learning, Slow Learners, Mathematics
eISSN: 2398-4287© 2021. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v6iSI4.2904