bluuebunny/crossref_metadata_2025 huggingface dataset:
Shwannoma de retroperitônio: um relato de caso
Authors: Morais Marta Helena , Ale Ananda Castro Chaves , Palomino Joana Muñoz , Almeida Rodrigo Oliveira de , Pereira Thayane Vidon Rocha , Pinto Arlene dos Santos , Boas Lenisa Cezar Vilas
Published: July 2024

Introdução: O schwannoma retroperitoneal é um tumor raro que se origina nas células de Schwann dos nervos periféricos e está localizado na região retroperitoneal. Devido à sua raridade, o diagnóstico requer alta suspeita clínica e deve ser considerado como um possível diagnóstico diferencial para qualquer massa retroperitoneal. Pacientes com histórico prévio de malignidade precisam ser investigados cuidadosamente, especialmente se o tumor estiver localizado intra-abdominalmente. A ressecção cirúrgica de lesões retroperitoneais apresenta altos riscos e deve ser decidida em conjunto com uma equipe radiocirúrgica. A confirmação do diagnóstico é obtida por meio de análise histológica, que é o método definitivo. Médicos devem estar cientes de que o schwannoma retroperitoneal pode se assemelhar a outras doenças, o que pode levar a um diagnóstico equivocado e tardio. Materiais e métodos: Os dados foram obtidos por meio de revisão de prontuário da paciente, exames complementares da mesma e revisão de literatura. Relato de caso: Paciente iniciou um quadro de dor abdominal tipo aperto e fisgadas leves em mesogástrio, sem relação com a alimentação, com melhora espontânea ou ao uso de analgésicos comuns. Houve piora progressiva da dor, o que levou a paciente a procurar o serviço de Gastroenterologia. Ao exame físico notou-se uma massa palpável em mesogástrio, pouco móvel, mal definida e indolor à palpação. Demais exame físico sem alterações significativas. Foi submetida à tomografia computadorizada de abdome que possibilitou a visualização de uma formação expansiva sólida medindo 6,3cm X5,3cmX4,8cm (Figura 1), localizada em retroperitônio, no andar superior do abdome, localizada entre a veia cava e a aorta, em contato com o aspecto posterior da cabeça do pâncreas, póstero-inferior à confluência da veia renal esquerda na aorta e anterior às artérias renais direitas. Foi então realizada laparotomia exploradora, sendo optado pela não retirada da lesão tendo em vista a estrita relação com vasos importantes do abdome. Realizaram-se biópsias da lesão para estudo histopatológico que revelou tratar-se de neoplasia composta por células fusiformes, distribuídas em fascículos curtos ou de forma desordenada, com áreas mais celulares e outras menos, em estroma colagenizado, com agregados linfoides associados, com expressão difusa da proteína S-100, compatível com Schwannoma. Conclusão: O diagnóstico de schwannoma na região retroperitoneal exige um alto nível de suspeita e uma avaliação clínica criteriosa. Devido à sua raridade, o schwannoma retroperitoneal deve ser considerado como um possível diagnóstico diferencial para qualquer massa nessa área. Apesar de geralmente apresentarem bom prognóstico, existe o risco de recorrência e transformação maligna. Sendo assim, requerem  acompanhamento médico por longo período.
Aprendiendo de la experiencia del Banco de Alimentos de Madrid: 30 años trabajando en proyectos de voluntariado para ayudar a las personas vulnerables
Authors: Ríos Ignacio de los Ríos , Sánchez Carmen Polo , Nuño Carlos Mur
Published: July 2024

Durante las últimas tres décadas, la labor desempeñada por el Banco de Alimentos de Madrid ha suscitado un renovado interés en el análisis de los elementos clave que han propiciado su exitosa trayectoria. Si bien, el debate en torno a las organizaciones homólogas ha cobrado relevancia a nivel internacional, particularmente en períodos de turbulencia económica (como la pandemia COVID19 y los conflictos de Ucrania y Palestina). Son escasos los estudios académicos que han examinado exhaustivamente los factores determinantes de gobernanza en la gestión (Takahashi, 2021) desde el punto de vista de la ejecución de proyectos y acciones, así como la estimación de su impacto en la sociedad.
Este artículo tiene como objetivo examinar, a través de un proceso de aprendizaje acumulado durante 30 años, la experiencia del Banco de Alimentos de Madrid, empleando el modelo Working With People (WWP) que integra el conocimiento experto y experiencial de los agentes involucrados en los proyectos y acciones. Analiza las diversas iniciativas llevadas a cabo; las grandes recogidas, operaciones kilo y jornadas de sensibilización como principales acciones ejecutadas.
Investigaciones recientes apuntan a que factores como la calidad de la información hacia los donantes, el apoyo del sistema y la idoneidad del proceso inciden positivamente en la satisfacción, confianza y retención, impactando finalmente en el rendimiento financiero de las organizaciones del Tercer Sector (Al-dmour et al., 2019). Además, cabe reseñar que las donaciones individuales a los Bancos de Alimentos se ven influenciadas por la percepción de las características de los beneficiarios y, entre otras, la frecuencia de las donaciones se determina por factores motivacionales (Bennett et al., 2021).
La importancia de estas instituciones se manifiesta no solo en la dimensión social sino también en la perspectiva de gobernanza y sostenibilidad, donde la participación de los agentes implicados, la adaptación a cambios y la adopción de tecnologías juegan un papel crucial para el éxito de los proyectos y acciones (Boonklum, 2023; Mossenson et al., 2023).
Los resultados obtenidos ponen de manifiesto el éxito en la dirección de los proyectos y los efectos generados en la población desde su fundación en 1994. En los últimos años, la creación de nuevos vínculos entre la Universidad y la Empresa, como la Cátedra Bancos de Alimentos-UPM, ha ampliado el alcance de sus proyectos y acciones. La generación de confianza en la sociedad, su estructura organizativa sólida y su valioso capital humano se erigen como los principales factores de credibilidad en la gobernanza, logrando atender diariamente a 137.124 personas y 540 entidades durante el año 2023.
Exploring the Interplay between the Warburg Effect and Glucolipotoxicity in Cancer Development: A Novel Perspective on Cancer Etiology
Authors: Akl Maher Monir , Ahmed Amr
Published: June 2024

The Warburg effect, first observed by Otto Warburg in the 1920s, delineates a metabolic phenomenon in which cancer cells exhibit heightened glucose uptake and lactate production, even under normoxic conditions. This metabolic shift towards glycolysis, despite the presence of oxygen, fuels the energy demands of rapidly proliferating cancer cells. Dysregulated glucose metabolism, characterized by the overexpression of glucose transporters and the redirection of metabolic pathways towards glycolysis, lies at the crux of this metabolic reprogramming. Consequently, the accumulation of lactate as a byproduct contributes to the creation of an acidic tumor microenvironment, fostering tumor progression and metastasis. However, recent research, notably proposed by Maher Akl, introduces a novel perspective regarding the role of glycolipids in cancer metabolism. Akl’s glucolipotoxicity hypothesis posits that aberrant glycolipid metabolism, specifically the intracellular buildup of glycolipids, significantly influences tumor initiation and progression. This hypothesis underscores the disruptive impact of accumulated glycolipids on cellular homeostasis, thereby activating oncogenic pathways and promoting carcinogenesis. This perspective aims to synthesize the intricate mechanisms underlying both the Warburg effect and glucolipotoxicity, elucidating their collective contributions to tumor growth and malignancy. By comprehensively understanding these metabolic aberrations, novel avenues for therapeutic intervention targeting the fundamental drivers of cancer initiation and progression emerge, holding promise for more efficacious treatment strategies in the future.
Management of severe hyponatremia in a chronic kidney disease patient; a case report
Authors: Qasem Anass , Rabbani Syed Arman , Kurian Martin Thomas , Sridhar Sathvik B
Published: June 2024

Hyponatremia is a common electrolyte abnormality in chronic kidney disease (CKD). Managing severe hyponatremia in CKD is challenging, requiring the correction of biochemical imbalances and fluid overload, often through traditional hemodialysis. However, this can lead to rapid serum sodium correction, potentially causing neurological complications. We present a case of a CKD patient with a suspected stroke, who exhibited dizziness, confusion, and an unsteady gait, and was found to have azotemia, metabolic acidosis, and severe hyponatremia (101 mmol/L). We managed the case by gradually correcting the serum sodium with hypertonic saline. Subsequently, we initiated traditional hemodialysis using a dialysate sodium concentration of 130 mEq/L when the serum sodium levels increased to 122 mmol/L. The patient was discharged in a vitally and hemodynamically stable condition, with a serum sodium level of 137 mmol/L. This report highlights the intricacies of managing severe hyponatremia in a CKD patient with a suspected stroke.
Twin neurological enigmas radiological and medical insight into a dual encounter with metformin induced encephalopathy
Authors: Ancilla Leyole Claudine , Sundaram Bala , Pathak Nabadwip , Raj Arawinth
Published: June 2024

Metformin induced encephalopathy is an infrequent but critical neurological complication associated with metformin therapy. Lentiform fork sign, an infrequent radiological imaging (MRI), presents a distinctive image in basal ganglia pathology. It manifests as a V-shaped or fork-like hyperintensity in the globus pallidus and putamen regions. While it has been associated with various conditions like diabetic uremic encephalopathy, toxins like methanol and ethylene glycol, Neurodegenerative etiologies. Its occurrence following metformin administration remains rare because of contraindication of prescribing metformin in a hemodialysis patient due to its well-known side of lactic acidosis. This abstract aims to report and discuss two cases presenting the lentiform forks sign following metformin administration in patients undergoing hemodialysis due to end-stage renal disease. Symptomatic involvement of basal ganglia as metformin induced encephalopathy and resolution with clinical recovery following hemodialysis are rarely reported. We hereby report two such cases which shows symptomatic improvement clinically as well as radiologically following hemodialysis
Severe respiratory acidosis contributing to refractory hyperkalemia: a case series of COVID-19 patients with renal failure
Authors: Pathak Nabadwip , Nanda Sunil Kumar
Published: June 2024

Introduction: Respiratory acidosis (RA) is not known to cause severe hyperkalemia. However, an exception to this general rule was observed in three patients with severe COVID-19 complicated with renal failure in our center. Objectives: The current study investigated the explanation for hyperkalemia refractory to renal replacement therapy in patients with severe COVID-19 with hypercarbia and renal failure in a tertiary care center. Patients and Methods: In this study, we present a case series of three patients with severe COVID-19 with hypercarbia and dialysis-requiring renal failure who developed persistent hyperkalemia refractory to renal replacement therapy. We studied various causes of persistent hyperkalemia, such as acid‒base disorder, a high turnover state, exogenous administration, rhabdomyolysis, and hypoaldosteronism. Results: All three patients initially presented with episodes of severe hyperkalemia, which were ameliorated after RA was corrected. All of these patients had worsening pulmonary function, after which the hyperkalemia could not be corrected, corresponding to persistent RA. The evidence that there was a contribution of RA to hyperkalemia was further strengthened by the observations of patient 1, in whom the hyperkalemia was only corrected after changing ventilator settings and who was unresponsive to dialysis. We studied the dialysate effluent in patient 3, and the results showed satisfactory removal of potassium with no improvement in the high serum potassium levels. Another interesting finding was that although the dialysate sodium concentration was greater than the serum sodium concentration, there was a decrease in the serum sodium concentration, indicating a reduced movement of sodium into the extracellular space. Conclusion: In our study, metabolic acidosis alone could not explain the high serum potassium levels. Moreover, hyperkalemia was corrected after RA was corrected, indicating that the latter might have been the predominant cause of hyperkalemia in these scenarios. The presence of renal failure and low serum bicarbonate levels might have been the factors contributing to decreased Na+-K+-ATPase activity in the setting of RA, which contributed to severe hyperkalemia in all three patients.
The association between the utilization of SGLT2 inhibitors and diabetic retinopathy; a systematic review and meta-analysis of cohort studies
Authors: Barkhordari Shahriar , Ghaffariyan Shahrzad , Banei Farzin , Shirvani Mohammad , yazdanjou Farangis , Ghaseminejad Kermani Sara , Akbari Mohammad , Baghaei Alireza , Mohammadtabar Mobin
Published: June 2024

Introduction: Diabetic retinopathy is one of the principal causes of blindness globally. The impact of sodium-glucose cotransporter 2 (SGLT-2) inhibitors, a category of anti-diabetic medications, on diabetic retinopathy remains undetermined. Consequently, this study aimed to examine the association between the utilization of SGLT2 inhibitors and the incidence of diabetic retinopathy. Materials and Methods: This investigation systematically searched databases, including Web of Science, Cochrane, ProQuest, PubMed, and Google Scholar, until March 7, 2024. A systematic review and meta-analysis methodology was employed. Data were analyzed using STATA software version 14, considering a significance level of tests at P<0.05. Results: The application of SGLT2 inhibitors was connected with a diminished diabetic retinopathy risk (odds ratio [OR]: 0.77, 95% CI: 0.69, 0.86). Among women, SGLT2 inhibitor use did not notably influence diabetic retinopathy risk (OR: 0.84, 95% CI: 0.69, 1.03). However, among men, employing SGLT2 inhibitors decreased the risk (OR: 0.81, 95% CI: 0.71, 0.92). In comparison to dipeptidyl peptidase-4 inhibitors (OR: 0.70, 95% CI: 0.53, 0.94) and pioglitazone (OR: 0.75, 95% CI: 0.74, 0.76), SGLT2 inhibitors lowered the risk of diabetic retinopathy. However, when compared to sulfonylureas (OR: 0.45, 95% CI: 0.17, 1.17) and GLP1-RA (OR: 0.70, 95% CI: 0.42, 1.17), SGLT2 inhibitors did not notably affect diabetic retinopathy. Moreover, using SGLT2 inhibitors in the age groups of 50-54 years (OR: 0.74, 95% CI: 0.55, 0.98), 55-59 years (OR: 0.65, 95% CI: 0.53, 0.79), and 60-64 years (OR: 0.89, 95% CI: 0.82, 0.97) was linked to lower diabetic retinopathy risk. Nevertheless, in the 65-69 age group, SGLT2 inhibitor administration did not significantly alter the diabetic retinopathy risk (OR: 1.04, 95% CI: 0.94, 1.15). Conclusion: The intake of SGLT2 inhibitors has been linked to a diminution in the hazard of diabetic retinopathy. However, further research in this domain is recommended, given the need for studies examined. Registration: This study has been compiled based on the PRISMA checklist, and its protocol was registered on the PROSPERO (CRD42024523959) and Research Registry (UIN: reviewregistry1808) website.
The relationship between metformin administration and age-related macular degeneration; a systematic review and meta-analysis of observational studies
Authors: mashaf Abdulateef Abdulkadhium , Othman Mohammed Abdul-Mounther , Kassid Omer Mansib , Aljibori Hakim S. Sultan , kadhum Abdul Amir H , Mohammed Ahmed Ali , Mhaibes Raed Muslim
Published: June 2024

Introduction: Vision loss due to age-related macular degeneration (AMD) is a major and growing health issue. Given that no definitive treatment is available for AMD, this study aims to evaluate the association between metformin use and AMD risk using a systematic review and meta-analysis approach. Materials and Methods: In this study, databases including ProQuest, PubMed, Web of Science, Cochrane, and Google Scholar search engines were searched without time restriction until April 20, 2024, based on PRISMA statement guidelines. Data were analyzed using STATA 14 software at a significance level of P < 0.05. Results: Overall, metformin administration reduced the risk of AMD (OR: 0.86, 95% CI: 0.80, 0.94). Concerning the dosage, a metformin dose of 1-270 g per 2 years (OR: 0.93, 95% CI: 0.90, 0.96) and 271-600 g per 2 years (OR: 0.91, 95% CI: 0.89, 0.94) mitigated the risk of AMD. Metformin use in women increased the risk of AMD (OR: 1.14, 95% CI: 1.09, 1.18). However, no significant relationship was noticed between metformin use and AMD risk in men (OR: 0.86, 95% CI: 0.73, 1.01). In addition, metformin was associated with a lower risk of AMD in case-control (OR: 0.93, 95% CI: 0.89, 0.97) and cohort (OR: 0.69, 95% CI: 0.51, 0.95) studies. Likewise, metformin use was associated with a lower risk of AMD in the age groups of 50-59 years (OR: 0.54, 95% CI: 0.50, 0.58) and 70-79 years (OR: 0.90, 95% CI: 0.84, 0.97). Conclusion: Metformin administration lowered the risk of AMD by 14%. Moreover, female gender was identified as a risk factor for AMD development. However, further studies are required on this subject to reach a definite conclusion. Registration: This study has been compiled based on the PRISMA checklist, and its protocol was registered on the PROSPERO (ID: CRD42024539904) and Research Registry (UIN: reviewregistry1824) website.
Association between triglyceride-glucose index and risk of chronic kidney disease: a systematic review and meta-analysis
Authors: Ali Muhanad Muhussin , Mhaibes Raed Muslim , Othman Mohammed Abdul-Mounther , R. Lahhob Qais , Qasim Mohammed Jasim
Published: June 2024

Introduction: The triglyceride-glucose index (TyG) is a reliable alternative marker for insulin resistance. Since insulin resistance is a risk factor for chronic kidney disease (CKD). Objectives: This study aimed to investigate the relationship between the TyG index and CKD using the systematic review method and meta-analysis. Material and Methods: The required sources were searched using the databases Cochrane, Web of Science, PubMed, ProQuest, and Google Scholar Search Engine without a time limit. STATA 14 software was conducted for data analysis, and tests with p-values lower than 0.05 (P < 0.05) were considered statistically significant. Results: Findings from 20 research with a total of 277986 samples demonstrated that high TyG index increased the risk of CKD in the total population, female patients, and male patients by 37% (OR: 1.37, 95% CI: 1.25, 1.5), 38% (OR: 1.38, 95% CI: 1.19, 1.61), and 31% (OR: 1.31, 95% CI: 1.13, 1.50), respectively. Furthermore, high TyG levels in individuals younger than 55 and those aged 55 or higher increased the risk of CKD by 54% (OR: 1.54, 95% CI: 1.36, 1.74) and 23% (OR: 1.23, 95% CI: 1.14, 1.32), respectively. Nevertheless, Australia (OR: 1.68, 95% CI: 1.56, 1.81) indicated the strongest and Singapore (OR: 1.21, 95% CI: 1.06, 1.38) showed the weakest relationship between the TyG index and the risk of CKD. However, higher TyG indices increased the risk of CKD in cohort and cross-sectional studies by 35% (OR: 1.35, 95% CI: 1.20, 1.51) and 41% (OR: 1.41, 95% CI: 1.29, 1.55), respectively. Conclusion: A high TyG index increases the risk of CKD, and women and individuals younger than 55 are the high-risk groups. Registration: This study has been compiled based on the PRISMA checklist, and its protocol was registered on the PROSPERO (ID: CRD42024544037) and Research Registry (UIN: reviewregistry1829) website.
Comparative histological and clinical differences between children and adults in IgA nephropathy
Authors: Zandifar Samaneh , Khayyat Azadeh , Zahmatkesh Arefeh , Esmaeil pour Mohammad Ali
Published: June 2024

IgA nephropathy (IgAN), as an autoimmune-mediated kidney disease worldwide, is considered an important cause of end-stage renal disease in adults. The most important diagnostic method in the patients is the evaluation of the biopsy findings. To date, several studies have examined different histopathological findings in patients with IgAN with an attempt to find out the relationship between morphologic findings with outcome and disease progression. Although there have been limited reports of IgAN in children, the Oxford scoring system is currently the most widely used IgAN classification and is validated for use in children and adults. In this review, we examined the most frequently published pathological findings on IgAN with a focus on Oxford classification between adults and children and attempted to highlight the key differences. The main purpose of this study was to assess the prognosis of patients with IgAN in childhood and adulthood, with emphasis on pathological risk factors for disease progression. Our results indicated that acute glomerulonephritis in children was predominantly reported more than chronic lesions. In addition, mesangial and endocapillary lesions were more common in children than in adults. In contrast, glomerular sclerosis, tubular atrophy/interstitial fibrosis, and atherosclerotic lesions were more common in older individuals.
The effects of different plant extract supplementation into drinking water egg laying performance and egg quality in second production cycle
Authors: Gümüş İbrahim Halil , Çil Güner , Sözcü Arda
Published: June 2024

This study aimed to investigate the effects of different plant extract supplementation into drinking water egg laying performance and egg quality parameters in second production cycle under commercial conditions. A total of 16657 Nick Brown laying hens in a second production cycle, kept in free-range system, used in the experiment between 75-83 weeks of age. The experimental groups were consisted of three treatment: CONT - control group (no supplementation), PEXT1 - combination of artichoke (Cynara scolymus) and turmeric (Curcuma longa) supplementation, PEXT2 – combination of cinnamon (Cinnamomum venum) + echinacea (Echinacea purpurea) + turmeric (Curcuma longa) supplementation as liquid form into drinking water. The supplementation was performed twice on weekly basis with an amount of 1 l / ton drinking water. The mean value of hen-housed and hen-day egg production, and egg weight were interestingly increased in the control group, than the PEXT1 and PEXT2 groups. However, a more efficient of FCR was found for the PEXT2 group. The breaking strength was found to be the highest
in the eggs of PEXT1, whereas a higher value for shell thickness was observed in PEXT1 and PEXT2 groups. Egg yolk had a darker tone in the PEXT1 and PEXT2 groups. According to the results of the present study, it could be concluded that using a combination of cinnamon, echinacea and turmeric could improve feed efficiency. Furthermore, supplementation of plant extracts enhanced the egg quality, namely shell strength and yolk color, during the second cycle of egg production.
Different concentrations of high fructose corn syrup in broiler diet cause different effects on selected hematological parameters
Authors: Altuğ Taha , Şen Gökhan , Kabakçı Ruhi
Published: June 2024

This study was aimed to investigate how the consumption of high fructose corn syrup (HFCS) affects blood parameters of broilers. Total 120 chickens were divided into three groups including 4 subgroups in each with free access to food and water for 42 days. The control group received no additional treatment, while the second and third groups were fed diets containing 5% or 10% HFCS, respectively. On the last day, broilers were euthanized, and 5 mL blood samples were collected for hematological analyses. Results indicated no significant differences in red blood cell (RBC) or hemoglobin (HGB) levels between the control and 5% or 10% HFCS- treated groups. However, 10% HFCS treatment significantly increased packed cell volume (PCV) and mean corpuscular volume (MCV), while 5%-HFCS increased mean corpuscular hemoglobin (MCH) and decreased mean corpuscular hemoglobin concentration (MCHC) compared to the control group. Total leukocyte counts (TLC) and monocyte values remained unaffected by HFCS treatments. Notably, 5% HFCS treatment increased basophil, heterophil, and
heterophil/lymphocyte ratio while decreasing lymphocyte. Conversely, 10% HFCS treatment reduced eosinophil and heterophil, increasing lymphocyte counts. In conclusion, our study suggests that dietary fructose intake can modify certain hematological parameters, potentially serving as early indicators of future systemic or metabolic issues.
PROVAS INOMINADAS CONTÁBEIS NO PROCESSO TRIBUTÁRIO: uma análise de modalidades atípicas
Authors: Lopo Martinez Antonio
Published: June 2024

O artigo realiza uma ampla abordagem acerca das provas atípicas ou inominadas na seara contábil, explorando suas modalidades, limitações e valor probante. Analisa a admissibilidade e aplicação de provas testemunhais, periciais, confissões extrajudiciais e elementos probatórios consuetudinários, como costumes e convenções contábeis, trazendo exemplos e citações doutrinárias. Defende a necessidade de maior debate sobre provas atípicas, trazendo nova luz a aspectos pouco explorados como testemunhos, confissões e usos contábeis. O texto se destaca pelo enfoque sistemático, conexões com o plano concreto e estrutura didática valiosa para acadêmicos e profissionais.
The Martyrial Face of The Salvadorean Church from The Theological Biographies of Óscar Romero and Ignacio Ellacuría
Authors: Mauti Ricardo Miguel
Published: June 2024

The purpose of this study is to present the relationship established between liberation and martyrdom in the Salvadorean Church. The angle of analysis is the theological biographies of Óscar Romero and Ignacio Ellacuría, both martyrs of El Salvador. The method of theological biography, in this case, allows theology not only to verify the announcement of the Kingdom as proposed by the Gospel of Jesus Christ, but also discovers a new contribution in the way of interpreting these nuclei of Christian revelation. Liberation and martyrdom are fundamental realities for liberation theology, and they endow it with a specific direction and pathos. Their commitment and denunciation of social injustice constitute a prophetic dimension that serves as a model for an entire local church and in particular for the ordained ministry. I am going to present my work with the formulation of three questions: the link between liberation and martyrdom (2), martyrs and the ordained ministry today (3), the problem of the Universal Church for a reception of the martyrs of justice (4), and some open conclusions.
The Gospel's Seeds in Massuru Culture
Authors: Linggi' Lius Bongga , Surbakti Pelita Hati
Published: June 2024

Awareness of the unfair treatment of local cultural contexts in the Christian mission movement during the colonial era is increasing in many communities. This is influenced by the church's increasing awareness of the richness of local culture itself. The Gereja Toraja is also part of that reality. For this reason, the Gereja Toraja has made various breakthroughs to give more place to local culture in carrying out the mission of the church. A number of activities and documents produced clearly show the face of The Gereja Toraja with a more friendly paradigm to local culture. However, this excellent breakthrough still needs to be shifted to the realm of practice and concreteness. This is because the paradigm in question is still dominated by theoretical matters. Through this paper, the author raises Massuru's culture as a case study. Through the efforts of contextual theology with an anthropological model, the author found that in the Massuru's culture, the gospel value contained in Matthew 5:23–24 is reconciliation before performing religious rites. Based on this result, the effort to shift the new paradigm in a more concrete direction within the Gereja Toraja will be more interesting and passionate. In turn, Torajan Christians will hopefully be more encouraged to put the message of the Bible into practice and enjoy their faith within the framework of their own culture.
Religions and Cultural Practices
Authors: Khosa-Nkatini Hundzukani P. , Mbiada Carlos Joel Tchawouo
Published: June 2024

South Africa is guided by the Constitution which entrenches equality among citizens, regardless of gender, race, religion or political affiliation. In the same vein, the Constitution also recognizes the right to practise one’s religion and culture. Religious and cultural practices must respect the diversity of the society. Such respect must also be observed within the community and religious spectrum. It is in this perspective that this paper investigates whether religious and cultural practices are carried out equally within the Black community. The authors, through a review of literature and observations carried out within the Black community, found systemic violations and discriminatory practices between men and women. The authors found that women are being subjected to abuse in the name of culture and that some practices, such as cleansing ceremonies, violate their dignity. The authors recommend a degree of fairness in cultural practices and that both genders should be subjected to the same practices or treated equally.
Non-Hormonal Approach to the Correction of Early Postmenopausal Disorders in Women with Insomnia
Authors: Станько Д.Э. , Добрук Е.Е. , Чиккер Л.Г. , Войнюш Ю.И. , Ленец Е.А.
Published: June 2024

Климактерические расстройства ранней постменопаузы имеют очевидную связь с нарушениями выработки нейротрансмиттеров, что позволяет эффективно использовать фитоэстрогены для лечения расстройств, ассоциированных с менопаузой. Изофлавоны красного клевера проявляют достаточную эффективность в дозе 40 мг на симптомы (достоверное улучшение вазомоторного, соматического, психосоциального и сексуального компонентов качества жизни в 1,08–1,64 раза) при приеме в течение 12 недель. Продемонстрирован приемлемый профиль безопасности их использования при длительном применении не менее 12 недель.

Climacteric disorders of early postmenopause have a clear association with impaired neurotransmitter production, suggesting that phytoestrogens can be effectively used to treat menopause-associated disorders. Red clover isoflavones exhibit sufficient efficacy at a dose of 40 mg for symptoms (significant 1.08–1.64-fold improvement in vasomotor, somatic, psychosocial and sexual components of quality of life) when taken for 12 weeks. An acceptable safety profile of their use in long-term use for at least 12 weeks has been demonstrated.
Peculiarities of Neonatal Hemostasis in Normal and Pathological Conditions
Authors: Устинович Ю.А. , Белкин А.М. , Снопкова М.С. , Стрижак М.И. , Смирнова Л.Б. , Ломская И.В. , Лебедько А.А.
Published: June 2024

Система гемостаза новорожденных детей отличается от взрослых. Значительные количественные и качественные различия факторов свертывания крови, особенности строения и функции тромбоцитов предопределяют свой, особый характер гемостаза. При этом в норме система сбалансирована и функционирует хорошо. При нарушениях свертываемости крови у врачей нередко возникают затруднения при интерпретации показателей гемостаза у новорожденных. Кроме того, при необходимости заместительная терапия проводится препаратами крови взрослых доноров, что имеет свои особенности. Статья посвящена обзору современных знаний по данной проблеме.

The hemostatic system of newborn children differs from that of adults. Significant quantitative and qualitative differences in blood coagulation factors, structural features and function of platelets predetermine their own special nature of hemostasis. At the same time, the system is normally balanced and functions well. In cases of bleeding disorders, doctors often have difficulty interpreting hemostasis indicators in newborns. In addition, if necessary, replacement therapy is carried out with blood products from adult donors, which has its own characteristics. The article is devoted to a review of modern knowledge on this issue.
The use of an automatic fire extinguishing system with thinly sprayed water for extinguishing live electrical equipment
Authors: Солоненко А.М.
Published: July 2024

В статья рассмотрена проблема применения автоматических установок пожаротушения для тушения электрооборудования под напряжением на объектах энергетики. Проведена серия экспериментов по определению тока утечки по струе огнетушащего вещества и на корпусе автоматической установки пожаротушения тонкораспыленной водой. Получены уравнения линейной регрессии, описывающие зависимость тока утечки от интенсивности подачи тонкораспыленной воды. Для проведения экспериментальных исследований был создан специальный стенд, который позволяет измерить величину тока утечки на корпусе автоматической установки пожаротушения и по струе огнетушащего вещества.

The article discusses the issue of using automatic fire extinguishing systems to put out electrical equipment that is under voltage in energy facilities. A series of experiments were conducted to determine the amount of current that flows through a stream of extinguishing agent and through the body of an automatic fire suppression system when using finely sprayed water. Linear regression equations were derived to describe the relationship between the amount of current and the intensity of the flow of finely dispersed water. For experimental research a special stand was created, which allows to measure the leakage current on the body of the automatic fire extinguishing unit and on the jet of extinguishing agent.
Bentuk dan Fungsi Mantra "Mangariau Banih"
Authors: Ma'ruf* Salim , Taqwiem Ahsani , Alfianti Dewi
Published: July 2024

This study aims to describe the forms and functions of the mantra “Mangariau Banih” of traditional farming communities in Pingaran Ulu Village, Astambul District, Banjar Regency. This study uses field research methods. This type of research is descriptive-qualitative. The data in this study is oral data. Sources of data in this study were informants (informants), namely Pingaran Ulu villagers who work as traditional farmers. Data collection techniques used in this study were interviews, recording and notes. Data analysis techniques in this study used qualitative data analysis techniques. The results of this study, in the form of seventeen mantras on the mangariau banih process, are divided into several forms and functions. Based on the results of this study, the forms in the Mangarau Banih mantra are 22 parts of the mantra in the form of repetition of sounds, 2 in the form of poetry, and 1 in the form of pantun. Meanwhile, the functions contained in the Mangarau Banih mantra include 21 parts of the mantra containing a religious function, 10 moral functions, 1 recreational function, and 1 aesthetic function.Keywords: form; function; Mangariau banih mantraAbstrak:Artikel ini akan mendeskripsikan bentuk dan fungsi mantra mangariau banih masyarakat petani tradisional di Desa Pingaran Ulu Kecamatan Astambul Kabupaten Banjar. Penelitian dilakukan dengan menggunakan metode penelitian lapangan. Jenis penelitian yaitu deskriptif-kualitatif. Data dalam penelitian ini merupakan data lisan. Sumber data dalam penelitian ini adalah masyarakat desa Pingaran Ulu yang berprofesi sebagai petani tradisional. Teknik pengumpulan data yang digunakan dalam penelitian ini berupa wawancara, rekam dan catat. Teknik analisis data dalam penelitian ini menggunakan teknik analisis data kualitatif. Hasil penelitian menemukan tujuh belas buah mantra pada proses mangariau banih, yang terbagi menjadi beberapa bentuk dan fungsi. Berdasarkan hasil penelitian ini, bentuk yang ada pada mantra mangariau banih adalah 22 bagian mantra berbentuk pengulangan bunyi, 2 mantra bentuk puisi, dan 1 mantra bentuk pantun. Sedangkan, fungsi yang terkandung dalam mantra mangariau banih meliputi 21 bagian mantra yang mengandung fungsi religius, 10 fungsi moralitas, 1 fungsi rekreatif, dan 1 fungsi estetis.Katakunci: bentuk; fungsi; mantra mangariau banih
ANALISIS KINERJA SIMPANG TIGA TAK BERSINYAL JALAN LINTAS BARAT SUMATERA (Studi Kasus Jalan Ahmad Yani - Jalan Pemuda Pringsewu)
Authors: Putra Fanky Arya , Herianto Dwi , Putra Sasana , Sulistyorini Rahayu
Published: July 2024

Bertambahnya jumlah kendaraan tanpa diiringi oleh peningkatan lebar jalan bisa menyebabkan terjadinya kepadatan lalu lintas dan akumulasi kendaraan di persimpangan jalan, terutama pada waktu jam sibuk. Simpang tiga tak bersinyal Jalan Ahmad Yani â€“ Jalan Pemuda merupakan pertemuan ruas jalan nasional dengan jalan kabupaten. Lokasi di sekitar persimpangan merupakan kompleks pertokoan dan pasar, sehingga pada jam tertentu arus lalu lintasnya sangat padat. Jalan Ahmad Yani merupakan salah satu ruas Jalan Lintas Barat Sumatera yang banyak dilewati oleh kendaraan berat dan sangat rawan akan terjadinya kecelakaan karena jalan tesebut memiliki lebar terbatas dan arus lalu lintas yang padat. Tujuan dari studi ini adalah untuk mengidentifikasi kinerja simpang tiga tak bersinyal di persimpangan Jalan Ahmad Yani - Jalan Pemuda serta menyajikan solusi yang efektif untuk mengatasi masalah yang ada di simpang tersebut. Pengumpulan data dilakukan dengan survei di lapangan berdasarkan Manual Kapasitas Jalan Indonesia 1997. Dari hasil analisis, didapatkan nilai kapasitas sebesar 2242 smp/jam, derajat kejenuhan sebesar 1,126, tundaan simpang sebesar 27,98 det/smp, peluang antrian antara 52,33% - 103,05%, dan tingkat pelayanan F. Solusi yang dapat dilakukan untuk mengatasi permasalahan pada simpang tiga tak bersinyal Jalan Ahmad Yani - Jalan Pemuda adalah larangan belok kanan dari Jalan Ahmad Yani (timur) dan larangan parkir dan berhenti di sepanjang pendekat simpang.
PENILAIAN KONDISI JALAN MENGGUNAKAN METODE SDI (SURFACE DISTRESS INDEX) PADA RUAS JALAN MATANI RAYA KABUPATEN KUPANG
Authors: BELA KRISANTOS RIA
Published: July 2024

Penilaian kondisi jalan merupakan langkah penting dalam menjaga kualitas jalan dan keselamatan pengguna jalan. Metode Surface Distress Index (SDI) merupakan salah satu metode yang digunakan dalam penilaian kondisi jalan. Data dikumpulkan melalui survei lapangan yang mencakup pengukuran kondisi permukaan perkerasan, retak-retak, kerusakan lainnya, kondisi saluran samping, dan lain-lain. Fokus penelitian ini adalah Jalan Matani Raya, Desa Penfui Timur, Kabupaten Kupang, NTT. Terutama pada Dusun 4 dengan panjang jalan sekitar Â± 3,67 km, dimulai dari STA 00+000 hingga STA 03+670. Berdasarkan hasil analisis data dan pembahasan, didapatkan nilai SDI pada Segmen 1 dan Segmen 3 berada pada rentang 0 < 50. Ini menunjukkan bahwa kondisi jalan baik (B). Pada Segmen 2, nilai SDI sebesar 105, berada pada rentang 100-150, yang menunjukkan kondisi jalan rusak ringan (RR). Sedangkan pada Segmen 4, nilai SDI sebesar 325, melebihi 150, yang mengindikasikan kondisi jalan rusak berat (RB). Berdasarkan penilaian tersebut, penanganan yang dianjurkan untuk Segmen 1 dan 3 adalah pemeliharaan rutin. Untuk Segmen 2, dianjurkan pemeliharaan berkala, sementara untuk Segmen 4, diperlukan peningkatan atau rekonstruksi jalan.Kata Kunci: Penilaian Kondisi Jalan, SDI, Jenis Penanganan
Students' Difficulty in Understanding Problems in the Contextual Problem-Solving Process
Authors: Samosir Christina Monika , Herman Tatang , Prabawanto Sufyani , Melani Rini , Mefiana Syifa Ananda
Published: July 2024

The main procedure that students need to master in the problem-solving process is understanding the problem before proceeding to the next steps. This research aims to investigate students' difficulties and the factors causing these difficulties in understanding the problem. This research is qualitative in nature and is based on the philosophy of phenomenology. The research was conducted in an eighth-grade class at one of the Junior High Schools in Bandung, consisting of 28 students. Data collection techniques included tests, interviews, and think-aloud methods. The data collection instruments used were tests and interview guides. The tests used in this research had been previously validated for content, construct, and face validity by mathematics education experts. Data analysis in qualitative research involves data reduction, data presentation, and drawing conclusions. The findings of this research indicate that the difficulties faced by students in understanding the problem include difficulties in comprehending language, difficulties in grasping both explicit and implicit meanings, difficulties in identifying the necessary information, and difficulties in connecting meanings. The main factors causing students' difficulties in understanding the problem are a lack of careful reading skills and a lack of understanding of the concepts held by students.
Bridging the gap: Examining parental involvement strategies and their impact on homework completion rates in mathematics
Authors: Nobis Martin Jr. , Caparroso Catherine L.
Published: June 2024

This research examines the influence of parental involvement tactics on students' mathematics homework completion rates, aimed at pinpointing crucial factors and evaluating the efficacy of such strategies. Utilizing a qualitative-quantitative approach, including with students, parents, and teachers, the study identifies distractions, workload, family obligations, and insufficient teacher support as significant barriers to mathematics homework completion. Time management, comprehension, and fatigue also play minor roles. The findings indicate that targeted parental involvement strategies can significantly enhance completion rates, with effective methods including accessible support, designated study spaces, breaking down assignments, fostering student autonomy, and leveraging technology. Additionally, parental involvement fosters stronger parent-child relationships, boosts student confidence, and promotes a positive attitude toward mathematics. To create a conducive learning environment, schools, teachers, and parents should collaborate, implementing recommendations such as creating quiet areas, promoting digital detox initiatives, managing workload, offering targeted support, establishing study environments, and setting clear expectations for mathematics practice.
Development of mathematics teaching materials: Internalizing Al-Qur'an, Hadith, Madurese culture, and religious moderation
Authors: Rosikhoh Dewi
Published: June 2024

The existence of a mandate from the Ministry of Religion regarding the integration of religious knowledge and science, as well as the internalization of religious moderation in every subject in class, had implications for the movement to develop learning media. One form of learning media was teaching materials. This development research aimed to design a fraction of teaching materials based on the al-Qur'an and hadith with internalizing religious moderation and Madurese culture for grade V elementary schools in Pamekasan and then test its validity. This research was development research using the ADDIE model. Meanwhile, testing the validity of teaching materials used expert and practitioner validation with questionnaire instruments. The research results showed that based on validation questionnaires for material experts, learning experts, Islamic religious experts, and practitioners, the teaching materials developed could be categorized as valid with an average score of 92%. Thus, teaching materials could be continued at the trial or field test stage. Apart from that, similar teaching materials could be developed on other mathematics topics at the elementary level, or similar teaching materials could be produced on the same issues but by internalizing the culture of each region.
Communication skills and mathematical disposition in implementing geogebra-assisted problem-based learning strategies
Authors: Khaidir Christina , Fitriza Rozi , Yumariza Ninik , Wahid Rahmatul
Published: June 2024

This paper aims to determine students' communication skills and mathematical disposition in implementing problem-based learning strategies using the Geogebra application. This type of research was a quasi-experiment with a control group design. The subjects of this research were classes A and B. The population in this research was all students in the odd semester 2023/2024 who were taking the Plane and Space Geometry course, which consists of two classes that were tested using the t-test with data from the student's final test. Based on calculations of the results of students' mathematical communication skills, specifically the experimental class 81.00 and the control class 71.16. Thus, students' mathematical communication abilities in problem-based learning assisted by Geogebra were better than those in conventional education. On the other hand, the results of students' mathematical disposition abilities were 76.59 for the experimental class and 68.16 for the control class. Thus, students' mathematical disposition abilities in problem-based learning assisted by Geogebra were better than those in conventional education.
IMPLEMENTATION OF MERDEKA MANDIRI CURRICULUM CHANGES IN ISLAMIC RELIGIOUS EDUCATION LEARNING AT UPT SMP NEGERI 2 GRESIK
Authors: Agustin Fia Ayu Putri , Amrullah Amrullah , Muqit Abd. , Yudi Usman
Published: June 2024

The Merdeka Mandiri curriculum is the curriculum chosen by UPT SMP Negeri 2 Gresik to implement the independent curriculum initiated by the Minister of Education and Culture, Nadiem Makarim. This research aims to determine the design of the Merdeka Mandiri curriculum that has changed Islamic Religious Education learning and the implementation of the Merdeka Mandiri curriculum that has changed the learning of Islamic Religious Education, as well as evaluate the Merdeka Mandiri curriculum that has changed in the learning of Islamic Religious Education. To achieve the objectives of this research, qualitative research was the choice to reveal the implementation of the independent learning curriculum, especially in Islamic Religious Education learning with the method used to collect data: interviews, observations, and documentation. Meanwhile, the data analysis techniques used are data condensation, data presentation, and concluding. The results of the research are the design of the Merdeka Mandiri Curriculum Changes in Islamic Religious Education learning in accordance with the central learning outcomes and developed by teachers in charge of Islamic Religious Education through teaching modules, the implementation of the Merdeka Mandiri Changed Curriculum in Islamic Religious Education learning is carried out in accordance with the teacher's understanding and when there are problems in the process solutions were sought for learning together through MGMPS Islamic Religious Education and teacher meetings. Evaluation of the Merdeka Mandiri Changed Curriculum for Islamic Religious Education learning was carried out internally from UPT SMP Negeri 2 Gresik and externally from the Education supervisor at the end of the semester.
PREDIKSI FINANSIAL DISTRESS DENGAN METODE ALTMAN Z-SCORE, ZMIJEWSKI, DAN GROVER PADA PERUSAHAAN SAWIT TERINDEKS SAHAM SYARIAH PERIODE 2020-2022
Authors: Hadi Abd , Dahruji Dahruji , Joni Joni
Published: June 2024

The primary aim of this research is to analyze the financial challenges encountered by sharia-compliant palm oil companies, along with assessing the variances in financial distress prognostications among the Altman Z-Score, Zmijewski, and Grover methodologies. Employing secondary data, this study adopts a descriptive quantitative approach. Data collection spans three years (2020–2022) utilizing a documentation strategy. Through purposive sampling, six companies are selected for analysis. Financial trouble predictions are conducted utilizing Altman Z-Score, Zmijewski, Grover, and One Way Anova methods prior to hypothesis testing. The study reveals disparate outcomes among the Grover, Zmijewski, and Altman Z-Score methodologies. Notably, the Zmijewski approach exhibits the highest accuracy rate of 83% among the predictive models for financial distress.