bluuebunny/crossref_metadata_2025 huggingface dataset:
The origin of heterogeneous sucrosic dolomite reservoir of the lower Permian Qixia Formation, NW Sichuan Basin, China
Authors: Jiang Nan , Wang Xingzhi , Xiao Dong , Liu Ran , Wang Wei , Zhao Like , Wang Xiaofang
Published: June 2023

Sucrosic dolomite, an important hydrocarbon reservoir, has long been the focus of carbonate sedimentological and reservoir geological studies. This study investigated a kind of heterogeneous sucrosic dolomite in the Lower Permian Qixia Formation of NW Sichuan Basin, which has recently been the location of giant natural gas discoveries. The heterogeneous sucrosic dolomite is characterized by coexistence of porous euhedral dolomite and tight anhedral dolomite, and it is mainly distributed in the platform-marginal shoal facies with a quasi-layered structure. Further geochemical analysis, including C, O, and Sr isotopes as well as rare earth elements, reveals that the euhedral dolomite and anhedral dolomite have similar geochemical properties to the matrix limestone representing coeval seawater, and they were mainly generated from dolomitization by the closed marine-related fluid (left-leaning REE and δPr < 1) in the shallow burial. The difference in crystal morphology, porosity, and permeability between the euhedral dolomite and anhedral dolomite is mainly related to the compositional and textural heterogeneities of the host rocks. Due to the dissolution of meteoric water (relatively flat REE and low Y/Ho) in the early diagenetic stage caused by high frequent exposures, quasi-layered vugs and caves were formed in the grainstones. In the process of shallow burial dolomitization, the loose-filled carbonate sands formed the porous euhedral dolomite due to sufficient space, while the matrix limestone formed the tight anhedral dolomite due to relatively poor porosity and permeability. Accordingly, the paleogeomorphic highland controlled platform-marginal shoal superimposed by meteoric water dissolution in the early diagenetic stage is the main factor for the formation of Qixia Formation reservoirs, while dolomitization is mainly manifested as the inheritance and adjustment of pre-existing pores in the host rock. Therefore, the exploration direction for dolomite reservoirs in the Qixia Formation in the Sichuan Basin should be shifted to the favorable sedimentary facies-controlled reservoir model, which can also be referential for other cases under similar geological setting.
Symptom Cluster Profiles in Adults with Chronic Obstructive Pulmonary Disease and Insomnia
Authors: Jun Jeehye , Park Chang , Fritschi Cynthia , Balserak Bilgay , Martyn-Nemeth Pamela , Kuna Samuel , Kapella Mary
Published: June 2023

Background:

People with chronic obstructive pulmonary disease (COPD) and insomnia may experience multiple symptoms that can affect physical function, but little research has focused on symptom clusters in this population.

Objectives:

This study aimed to identify subgroups of people with COPD and insomnia based on a pre-specified symptom cluster and determine whether physical function differed in the subgroups.

Methods:

This secondary data analysis included 102 people with insomnia and COPD. Latent profile analysis classified subgroups of individuals sharing similar patterns of five symptoms: insomnia, dyspnea, fatigue, anxiety, and depression. Multinomial logistic regression and multiple regression determined factors associated with the subgroups and whether physical function differed among them.

Results:

Three groups of participants were identified based on the severity of all five symptoms: low (Class 1), intermediate (Class 2), and high (Class 3). Compared to Class 1, Class 3 showed lower self-efficacy for sleep and for COPD management and more dysfunctional beliefs and attitudes about sleep. Class 3 showed more dysfunctional beliefs and attitudes about sleep than Class 2. Class 1 showed significantly better physical function than Classes 2 and 3.

Conclusions:

Self-efficacy for sleep and for COPD management and dysfunctional beliefs and attitudes about sleep were associated with class membership. As physical function differed among subgroups, interventions to improve self-efficacy for sleep and for COPD management and minimize dysfunctional beliefs and attitudes about sleep may reduce symptom cluster severity, in turn enhancing physical function.
Adaptive Robotic Information Gathering via non-stationary Gaussian processes
Authors: Chen Weizhe , Khardon Roni , Liu Lantao
Published: June 2023

Robotic Information Gathering (RIG) is a foundational research topic that answers how a robot (team) collects informative data to efficiently build an accurate model of an unknown target function under robot embodiment constraints. RIG has many applications, including but not limited to autonomous exploration and mapping, 3D reconstruction or inspection, search and rescue, and environmental monitoring. A RIG system relies on a probabilistic model’s prediction uncertainty to identify critical areas for informative data collection. Gaussian processes (GPs) with stationary kernels have been widely adopted for spatial modeling. However, real-world spatial data is typically non-stationary—different locations do not have the same degree of variability. As a result, the prediction uncertainty does not accurately reveal prediction error, limiting the success of RIG algorithms. We propose a family of non-stationary kernels named Attentive Kernel (AK), which is simple and robust and can extend any existing kernel to a non-stationary one. We evaluate the new kernel in elevation mapping tasks, where AK provides better accuracy and uncertainty quantification over the commonly used stationary kernels and the leading non-stationary kernels. The improved uncertainty quantification guides the downstream informative planner to collect more valuable data around the high-error area, further increasing prediction accuracy. A field experiment demonstrates that the proposed method can guide an Autonomous Surface Vehicle (ASV) to prioritize data collection in locations with significant spatial variations, enabling the model to characterize salient environmental features.
Effects of high-flow nasal cannula oxygen therapy for patients with acute exacerbation of chronic obstructive pulmonary disease in combination with type II respiratory failure
Authors: Liu Aiming , Zhou Yaqing , Pu Zunguo
Published: June 2023

Objective

To evaluate the therapeutic effects of high-flow nasal cannula (HFNC) oxygen therapy in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and type II respiratory failure.

Methods

Seventy-two patients with AECOPD and type II respiratory failure were randomly allocated to an HFNC oxygen therapy trial group or a non-invasive positive-pressure ventilator therapy (NIPPV) control group. Their arterial blood gas parameters and comfort, evaluated using a questionnaire, were compared before and after the therapeutic interventions.

Results

The PaCO2 and blood [Formula: see text] concentration of both groups were significantly reduced by the treatments, whereas the pH, PaO2 and PaO2/FiO2 were increased. The PaCO2 of the experimental group was significantly lower than that of the control group following treatment. The PaO2 of the experimental group was significantly higher than that of the control group. The tracheal intubation rates of the two groups did not significantly differ. After treatment, all the indices of comfort were rated higher in the HFNC group than in the NIPPV group.

Conclusions

HFNC has a good therapeutic effect in patients with AECOPD and type II respiratory failure. It improves patient comfort and has clinical value.
Design of innovated structure of wind energy system with reduced manufacturing cost and optimized efficiency
Authors: Tounsi Souhir
Published: June 2023

DC generators have the major drawback of the large number of sliding brush-collar contacts, making this motor structure expensive and requiring a non-negligible maintenance cost. To avoid this problem, an excitation system allowing the excitation current to be reversed after the electromotive force changes polarity is added. The structure of the generator is found by equivalence to a permanent magnet direct current generator structure by changing the magnets by equivalent concentrated coils. A control technique of this type of generator, used in a wind energy production system, is developed to show the efficiency of this type of generator in the field of wind energy production. Related to permanent magnets generators, the studied structure is with reduced production cost since the magnets are replaced by coils. The innovation aspects of the studied generator are the modularity (use of several modules to increase the power delivered by the generator), the elevated efficiency due to the limited number of power chain components, the elevated power to weight ratio, the simplicity of the control and the reduced manufacturing cost. In conclusion, the use of the studied generator in the wind energy system, makes the power chain simple, inexpensive and robust.
Shifting Narratives of Soil in Scientific Discourses of Colonial Assam Tea Plantations
Authors: Borkotoky Namrata
Published: June 2023

With the establishment of tea plantations in Assam in the first half of the nineteenth century, colonial tea planters and scientists began to examine ways to profitably produce tea for a growing global market. Apart from the visible landscape alterations through mass deforestation, tea monocultures also surreptitiously effected considerable transformation on its immediate physical environment, particularly on the soil. This paper highlights how the question of soil came under the purview of the colonial tea scientists when over the years, consequently and inevitably, these plantations showed a decline in the quality and quantity of tea produced. As a result, the initial conviction in the fertility of Assam’s soil within the tea discourse began to be replaced with discussions that revealed how plantation cultivation of tea itself was at the root of these problems in the late nineteenth and early twentieth centuries.
Book review: Santosh Kumar Rai, Weaving Hierarchies: Handloom Weavers in Early Twentieth Century United Provinces
Authors: Tripathi Ratnesh Kumar
Published: June 2023

Santosh Kumar Rai, Weaving Hierarchies: Handloom Weavers in Early Twentieth Century United Provinces (Delhi: Primus, 2021), xx + 515 pp., ₹1,595, ISBN: 9789390737758 (Hardback).
Meta-analysis of haematocrit and activated partial thromboplastin time as risk factors for unplanned interruptions in patients undergoing continuous renal replacement therapy
Authors: Zhang Kun , Liu Chunxia , Zhao Heling
Published: June 2023

Objective:

Although continuous renal replacement therapy (CRRT) is common, unplanned interruptions often limit its usefulness. Unplanned interruption refers to the forced interruption of blood purification treatment, the failure to complete blood purification treatment goals or the failure to meet blood purification schedule times. This study aimed to evaluate the effect of haematocrit and activated partial thromboplastin time (APTT) on the incidence of unplanned interruptions in critical patients with CRRT.

Methods:

A systematic review and a meta-analysis were performed by searching the databases of China National Knowledge Infrastructure, Wanfang, VIP, China Biomedical Literature, Cochrane Library, PubMed, Web of Science and Embase from their inception to 31st March 2022 for all studies with a comparator or independent variable relating to the unplanned interruption of CRRT.

Results:

Nine studies involving 1165 participants were included. Haematocrit and APTT were independent risk factors for the unplanned interruption of CRRT. The higher the haematocrit level, the greater the risk of unplanned CRRT interruptions (relative risk ratio [RR] = 1.04, 95% confidence interval [CI]: 1.02, 1.07, Z = 4.27, p < 0.001). The prolongation of APPT reduced the risk of unplanned CRRT interruptions (RR = 0.94, 95% CI: 0.92, 0.96, Z = 6.10, p < 0.001).

Conclusion:

Haematocrit and APTT are the influencing factors on the incidence of unplanned interruptions in critical patients undergoing CRRT.
Variations in Coparenting Quality Among Mexican American Families Based on Generational Status and Acculturation
Authors: Lindsey Eric W. , Sanchez Eva , Castro Noel
Published: June 2023

The purpose of this study was to examine Mexican-origin parent’s generational status and cultural orientation in relation to supportive and undermining coparenting behavior. Mothers and father from 126 Mexican-origin families (8% of mothers and 12% of fathers born in Mexico) with a preschool age child ( M = 38.80 months old; 60 boys, 66 girls) completed questionnaires assessing their generational status and cultural orientation. Mother-father-child triads were observed for supportive and undermining coparenting behavior. Both mothers and fathers of later generational status (i.e., who had lived longer in the US) had higher levels of undermining coparenting behavior. Mothers and fathers with greater Mexican cultural orientation had higher supportive coparenting behavior. Among Mexican-origin two-parent families, fathers of more recent generational status (i.e., who had immigrated to the US or had parents who immigrated to the US) and greater cultural orientation demonstrated more supportive and less undermining coparenting behavior. The results of this study suggest that both researchers and clinicians should make it a regular practice to conduct independent assessments of generational status and cultural orientation when focusing on contributing factors to the quality of co-parenting in Mexican-origin families.
The Role of Twitter in Radiology Medical Education and Research: A Review of Current Practices and Drawbacks
Authors: Katzman Benjamin D. , Farshait Nataly , Patlas Michael N.
Published: June 2023

The trends in society have provided favourable conditions for the rapid growth of radiology on social media, specifically there has been an expanding presence on Twitter. Currently, simple searches on Twitter yield a plethora of radiology education resources, that may be suited for medical students, residents or practicing radiologists. Educators have many tools at their disposal to deliver effective teaching. Over time, strategies such as including images and scrollable stacks often are more successful at gaining popularity or clicks online. Journals and authors can use Twitter to promote their new scientific work and potentially reach audiences they couldn’t have prior. Attendees at conferences can get involved in the conversation by tweeting about the meeting and engaging with other attendees with mutual interests. Interested medical students, residents and even practicing radiologists can use Twitter as a means of networking and connecting with other scholars all around the globe. Within its glory, Twitter does carry some drawbacks including privacy concerns, equality, and risk of misinformation. Above all, the future of Twitter is bright and promising for all who are currently on it and plan to use it for their education, research, or professional advancement.
Differential parametrization of rail vehicle properties and its impact on hunting
Authors: Vishnu S , Garg Shaswat , Singh SP , Saha SK
Published: June 2023

In this work, we have developed a serial-chain multibody model of a rail vehicle, using the Decoupled Natural Orthogonal Complement matrices. The governing equations of the system were linearized, and the start of hunting was identified by finding the Smallest Bifurcation Point (SBP) of the trivial solution. Uneven wear creates differences in the properties of similar components in a rail vehicle. It was found that such variations are neglected in the hunting analysis. Hence, we introduce these differences by independently changing 32 parameters. The study found that these variations lead to unique trends. Then, these trends were used to recommend design changes for a rail vehicle, which could be thought of, in order to improve the hunting characteristics. For this purpose, an interactive software tool was created to easily visualize, and manipulate the hunting behavior of a rail vehicle.
Development and validation of a risk prediction nomogram for disposition of acute clozapine intoxicated patients to intensive care unit
Authors: Sharif Asmaa F. , Aouissi HA , Kasemy Zeinab A. , Byeon H , Lashin Heba I.
Published: June 2023

Background

Clozapine is an atypical antipsychotic drug used for the treatment of refractory schizophrenia. It is reported as the most toxic in its class. Using serum clozapine level as a severity indicator is doubtful and unfeasible, particularly in low resourced countries.

Methods

This is an extended two-phase retrospective study that utilized medical records of patients diagnosed with acute clozapine intoxication and admitted to Tanta University Poison Control Center, Egypt during the past 6 years. Two hundred and eight medical records were used to establish and validate a nomogram for predicting the need for intensive care unit (ICU) admission in acute clozapine intoxicated patients.

Results

A reliable simple bedside nomogram was developed and proved its significant ability to predict the need for ICU admission, with an area under the curve (AUC) of 83.9% and 80.8% accuracy. It encompassed the age of admitted patients (AUC = 64.8%, p = .003), respiratory rate (AUC = 74.7%, p < .001), O2 saturation (AUC = 71.7%, p < .001), and random blood glucose level upon admission (AUC = 70.5%, p < .001). External validation of the proposed nomogram showed a high AUC (99.2%) with an overall accuracy of 96.2%.

Conclusion

There is a need to develop a reliable objective tool predicting the severity and need for ICU admission in acute clozapine intoxication. The proposed nomogram is a substantially valuable tool to estimate ICU admission probabilities among patients with acute clozapine intoxication and will help clinical toxicologists make rapid decisions for ICU admission, especially in countries with low resources.
A Bayesian genomic selection approach incorporating prior feature ordering and population structures with application to coronary artery disease
Authors: Dai Xiaotian , Lu Xuewen , Chekouo Thierry
Published: June 2023

Coronary artery disease is one of the most common types of cardiovascular disease. Death from coronary heart disease is influenced by genetic factors in both women and men. In this article, we propose a novel Bayesian variable selection framework for the identification of important genetic variants associated with coronary artery disease disease status. Instead of treating each feature independently as in conventional Bayesian variable selection methods, we propose an innovative prior for the inclusion probabilities of genetic variants that accounts for their ordering structure. We assume that neighboring variants are more likely to be selected together as they tend to be highly correlated and have similar biological functions. Additionally, we propose to group participating subjects based on underlying population structure and fit separate regressions, so that the regression coefficients can better reflect different disease risks in different population groups. Our approach borrows strength across regression models through an innovative prior inspired by the Markov random fields. The proposed framework can improve variable selection and prediction performances as demonstrated in the simulation studies. We also apply the proposed framework to the CATHeterization GENetics data with binary Coronary artery disease disease status.
Predictors of young people’s anti-vaccine attitudes in the context of the COVID-19 pandemic
Authors: Crescenzi-Lanna Lucrezia , Valente Riccardo , Cataldi Silvia , Martire Fabrizio
Published: June 2023

The objective of this research was to explore how attitudes to science and scientists may be related to anti-vax positions and whether the psychological trait known as Need for Closure may influence the relationship between any or all of these attitudes. A questionnaire was administered to a sample of 1128 young people aged 18–25 living in Italy during the COVID-19 health crisis. Based on the results of exploratory and confirmatory factor analyses, which allowed the extraction of a three-factor solution (scepticism about science, unrealistic expectations about science and anti-vax postures), we tested our hypotheses by means of a structural equation model. We found that anti-vax positions are strongly correlated with sceptical views of science, while unrealistic expectations about science affect attitudes to vaccination only indirectly. Either way, Need for Closure emerged as a key variable in our model, as it significantly moderates the effect of both factors on anti-vax positions.
Less Invasive Surfactant Administration in Preterm Neonates: A Single Centre Experience at a Tertiary Care Teaching Hospital
Authors: Patrikar Smruti , Arya Sunil , Prajapati Jyoti
Published: June 2023

Background

Less Invasive Surfactant Administration (LISA) minimizes the need for invasive ventilation. As a result, it might improve survival rates in preterm newborns with respiratory distress syndrome (RDS), reducing long-term complications. This study explored the efficacy and potential benefits of the LISA in preterm newborns and its effect on short-term morbidity and mortality.

Methods

In this prospective observational study, 104 eligible preterm newborns <35 weeks of gestational age were admitted to NICU from August 2020 to July 2021at a tertiary care teaching institute in central India with RDS were given surfactant using 5F feeding tube without intubation while spontaneously breathing on NCPAP. Regarding respiratory parameters, invasive ventilation in the first 72 hours of age, mean duration of both invasive ventilation and NCPAP, mean duration of oxygen requirement, complications, and neonatal outcomes were assessed.

Results

The mean duration of the NCPAP requirement and the mean total duration of the oxygen requirement were 41.77 hours and 81.3 hours, respectively. Twenty-seven neonates (25.96%) required invasive ventilation within 72 hours of age. Fourteen neonates (13.46%) required second dose of surfactant. Total mortality till NICU stay was 30.76% (n = 32). Incidences of surfactant reflux to the esophagus, desaturation during the intervention procedure, and procedure complications (pulmonary hemorrhage, pneumothorax) were also less during the LISA method.

Conclusion

LISA is an alternative, safe, and feasible method for surfactant delivery in spontaneously breathing preterm neonates on NCPAP. Therefore, adopting this procedure in a developing country to reduce short-term complications is possible. However, since a small number of neonates were included in this study, further extensive studies involving large numbers of preterm neonates and multiple centers are needed to generalize the results to the study population.
Book review: June Teufel Dreyer and Jacques deLisle (eds), Taiwan in the Era of Tsai Ing-wen: Changes and Challenges
Authors: Singh Sachin
Published: June 2023

June Teufel Dreyer and Jacques deLisle (eds), Taiwan in the Era of Tsai Ing-wen: Changes and Challenges, Series: Routledge Research on Taiwan series. Routledge, 2021, pp. 334, ₹13581 (hardcover), ₹2793 (Kindle), ISBN: 9780367366865 (hardback), ISBN: 9780429356469 (e-book).
The UK Infrastructure Bank and the financialization of public infrastructures amidst nationalist neoliberalism
Authors: McArthur Jenny
Published: June 2023

Literature on the financialisation of infrastructure gives limited attention to public banks. Since public banks are key state institutions to enable and shape financialisation, more research is needed to show how they mediate financialisation processes amidst evolving social, political and economic pressures. To address the gap in existing literature, this article develops a case study on the UK Infrastructure Bank to examine how the bank enables financialisation whilst maintaining credibility with the United Kingdom's neoliberal-nationalist regime. The findings show that the UKIB is a centralised, technocratic institution which deploys de-risking interventions to attract private investment, including guarantees, equity shares and debt financing. Yet, these interventions enable projects which offer limited public value, such as debt financing to fuel over-investment in fibre broadband markets, or equity investments in infrastructure funds which perpetuate the dominance of short-term, extractive investment logics. To maintain credibility with the neoliberal-nationalist regime, the UKIB's governance strengthens the central government's power over its activities, allowing it to shape the post-Brexit policy agenda and target investment to specific constituencies. While the UKIB boosts the profitability of infrastructure assets for private investors, it also exposes regions to extractive logics that undermine the potential public benefits. The findings show how public banks can be used to coordinate and bolster support for financialisation, yet, the use of de-risking interventions to catalyse financialisation is often at odds with generating long-term public value.
The poisoned father: Jane Campion’s The Power of the Dog and the unexpected relevance of Lacan to psychiatric practice
Authors: Stone Meredith
Published: June 2023

Objective

Lacan is often deemed an obscure theorist with little clinical application. However, in film studies his psychoanalytic theory has been highly influential. This paper is part of a series of articles published in this journal accompanying a psychiatry registrar teaching programme on film and psychodynamic concepts. It introduces the Lacanian ideas of the Symbolic, Imaginary and Real as they appear in Jane Campion’s The Power of the Dog, and discusses their societal and clinical significance.

Conclusions

A Lacanian reading of Power of the Dog offers insights into ‘toxic masculinity’. Furthermore, it demonstrates how clinical symptoms can represent an escape from socially mediated toxicities.
Ask and You Shall Receive: The Effects of Negativity and Fundraising Appeals on Facebook
Authors: Wintersieck Amanda , Keena Alex
Published: June 2023

Social media has transformed electoral politics and allows campaigns to micro-target supporters. However, little is known about the effectiveness of political ads on social media, particularly those that appeal for money. We study the fundraising effects of ad campaigns sponsored by a well-funded Super PAC, The Lincoln Project. Our model includes 100s of millions of ad impressions targeting Facebook users in the 50 states, plus D.C., over 308 days in 2020. We coded ads for tone and fundraising appeals and find that the most effective ads are those that directly appeal for money, while ads that use negativity are associated with a small, positive effect. Ads that include both negativity and fundraising appeals are associated with the most money: each impression yields an additional $0.52 in itemized donations (campaign contributions). The results confirm what previous research on campaign giving has found— people tend to give money to campaigns when they are asked to—and show how digital advertising influences political behavior.
Cooking at Home: Correlates of Frequency and Intention in Fifth Graders
Authors: Boucher Danielle , Beaulieu Dominique , Simard Dominic
Published: June 2023

Cooking at home is associated with health benefits, and 10- and 11-year-old children are capable of participating in meal preparation. However, opportunities for children to cook at home have declined. This study aimed to identify determinants of the frequency and the intention to cook at home in fifth graders using the Theory of Planned Behavior as a framework with quantitative methodology. A total of 241 participants across five elementary schools of the Chaudière-Appalaches region (Quebec, Canada) took part in this correlational study. Data were collected via a self-administered questionnaire based on the Theory of Planned Behavior. Regression analyses led to the identification of determinants of frequency and intention to cook at home. More than two-thirds of participants (69%) declared having cooked at home in the past 7 days. Intention was the only significant variable explaining 18% of the variance for frequency. Intention was determined by perceived behavioral control, attitude, descriptive norms, subjective norms, perceived barriers, being a girl, and normative beliefs, which explain 74% of the variance. Whereas other studies aiming at better understanding children’s involvement in meal preparation at home focused on self-efficacy for cooking, this study highlights other behavioral determinants. For example, support from parents appears to be crucial to promote this behavior in this age group. Future research and interventions should be oriented toward determinants such as subjective norms and normative beliefs, and focus on children’s autonomy.
Comparison of ultrasound-guided dynamic needle tip positioning and acoustic shadowing technique with palpation technique for radial arterial cannulation by experienced clinicians: A randomized controlled trial
Authors: Siddaramaiah Mruthyunjaya Nalluru , Sharma Ankur , Goyal Shilpa , Kumar Sandeep , Kumari Kamlesh , Goel Akhil Dhanesh , Bhatia Pradeep , Kothari Nikhil
Published: June 2023

Background:

Radial artery cannulation is usually done for monitoring invasive blood pressure during intraoperative period. The dynamic needle tip positioning approach allows continuous visualization of the needle tip during ultrasound-guided cannulation. The acoustic shadowing technique, using two lines on the ultrasound probe, might be used to facilitate radial artery puncture. We aimed to compare these two ultrasound-guided techniques of radial artery cannulation with the traditional palpation method in adult patients.

Methods:

In this trial, 180 adult patients requiring arterial cannulation were randomized into three groups (Traditional palpation (TP), Dynamic needle tip positioning (DNTP), and acoustic shadow technique (AST)). All cannulations were carried out by experienced anesthetists. Data was analyzed for the success rate of arterial cannulation in the first attempt, total number of attempts in 5 min, time taken to cannulate, number of cannulas used, and complications related to the procedure.

Results:

The first attempt success rates among TP, DNTP, and AST were 66.7%, 66.7%, and 71.7%, respectively ( p = 0.794). The median time taken for cannulation was 60.5 (37.0, 129.5) s, 71.0 (50.0, 170.0) s, and 108.0 (58.0, 181.0) s, respectively ( p = 0.066) and the median number of cannulation attempts was 1, in all the three groups ( p = 0.684). There was also no difference in the total number of cannulas used, the overall success rate of cannulation, and complications related to the procedure in the three groups.

Conclusion:

The TP, DNTP, and AST technique for radial artery cannulation had comparable first attempt success rate, the time taken for cannulation, the number of cannulas used, and overall complications. We conclude that radial arterial cannulation by palpation, as well as ultrasound-guided DNTP and AST techniques performed by experienced clinicians in hemodynamically stable adult patients are equally advantageous.
A Novel Inhibitor of DKK1/LRP6 Interactions Against the Alzheimer Disease: An Insilco Approach
Authors: Prajapat Manisha , Singh Harvinder , Chaudhary Gajendra , Sarma Phulen , Kaur Gurjeet , Prakash Patel Ajay , Medhi Bikash
Published: June 2023

The activation of the Wnt signaling pathway is implicated in a neuroprotective mechanism against the Alzheimer disease. When this pathway is blocked, it activates GSK3 beta, leading to tau hyperphosphorylation and the apoptosis of neurons. Dickkopf-related protein 1 (DKK1) is a protein that competes with the Wnt ligand for the low-density lipoprotein receptor–related protein 6 (LRP6) receptor’s binding, interrupting the Wnt-induced Fzd-Wnt-LRP6 complex. This counteracts Wnt’s neuroprotective effect and contributes to the progression of the Alzheimer disease. The aim of this study was to use in silico approach to develop new agents that can combat the Alzheimer disease by targeting the interaction between DKK1 and LRP6. To achieve this, we conducted a virtual screening (Vsw) of the Asinex-CNS database library (n = 54 513) compounds against a generated grid in LRP6 protein. From this screening, we selected 6 compounds based on their docking score and performed molecular mechanics-generalized Born surface area (MM-GBSA) binding energy calculations on the selected ligands. Next, we evaluated the Absorption, Distribution, Metabolism, and Excretion (ADME) results of the 6 screened compounds using the Quick prop module of Schrödinger. We then employed several computational techniques, including PCA (Principal Component Analysis), DCCM (Dynamic Cross-Correlation Map), molecular dynamics simulation, and molecular mechanics/Poisson-Boltzmann surface area (MM/PBSA)–based negative binding free energy (BFE) calculation, to further analyze the compounds. Our extensive computational analysis resulted in the identification of 3 potential hits, LAS 29757582, LAS 29984441, and LAS 29757942. These compounds were found to block the interaction of DKK1 with LRP6 (A and B interface) protein, and their potential as therapeutic agents was supported by negative BFE calculation. Therefore, these compounds show potential as possible therapeutic agents for treating the Alzheimer disease through targeting the interaction between DKK1 and LRP6.
Digital financialization and surveillance capitalism in the Global South: The new technologies of empire
Authors: Zulfiqar Ghazal Mir
Published: June 2023

This essay describes a hybrid form of contemporary colonization that involves the fusion of digital and financial realms to explore new frontiers in profit generation, governance, and control. While early research has explored this dual mode of financialization and surveillance capitalism, it primarily employs Western frameworks assuming a universalism that does not account for the coerced lived experiences of the digitally colonized across the Global South. Organization, with its commitment to providing critical epistemic space to non-Western subjectivities, should lead this quest by shining a light on the colonization of everyday spaces in the Global South, with the new technologies of empire.
What’s up with our obsession with the theoretical contribution: A means to an end or an end in and of itself?
Authors: Prasad Ajnesh
Published: June 2023

Knowledge production in the discipline of management and organization studies (MOS) is in a labyrinth of its own making. Over the last 30 years, scholars in the discipline have exhibited an intransigent obsession with the theoretical contribution. At this juncture, with Organization about to commence its fourth decade in publication, I would like to take the opportunity to pause as well as to reflect on some of the implications and the consequences that emanate from this obsession. Drawing on specific examples from MOS, I focus my analysis on three mechanisms through which the discipline’s obsession with the theoretical contribution poses unintended but detrimental outcomes on knowledge production: (1) unnecessary proliferation of theoretical constructs, (2) building theory upon theory rather than empirical validation, and (3) making theory for theory’s sake.
Using the 2016 Zika outbreak to estimate the potential tourism impacts of a Chikungunya event in Florida
Authors: Ferreira João-Pedro , D. Court Christa , Basurto-Cedeño Estefania , Pennington-Gray Lori
Published: June 2023

Chikungunya virus (CHIKV), a mosquito-borne illness, is increasing in prevalence worldwide, and experts have warned of the imminence of an outbreak in the Southern Gulf Region of the United States (U.S.). Tourist destinations such as Miami and Orlando in Florida are among the most likely places for an outbreak to occur. The decline in attractiveness of a destination due to the outbreak, combined with the restrictive measures implemented to combat the outbreak, have the potential to significantly impact tourism-dependent local economies. This study is unique in that it estimates the potential economic impacts on tourism of an unprecedented outbreak, in this case CHIKV events in the U.S. For this, declines in tourism that followed the 2016 Zika virus outbreak in the Wynwood area of Miami, Florida are assessed to provide insights on the potential size and scope of the shock on tourism resulting from a CHIKV event. Results suggest that a CHIKV outbreak can lead to losses of approximately US$ 30 million in sales and nearly 250 jobs in the Wynwood area alone. Other popular tourist destinations such as Orlando could suffer significant losses of more than 2,500 jobs and US$ 300 million in sales. Estimating the potential losses associated with tourism declines resulting from a CHIKV outbreak provides data and insights to decision-makers that are considering policy measures aimed at preventing, preparing for, or mitigating the impacts of such events. This is particularly relevant as new advances are being made in the development of a CHIKV vaccine.
Elucidating children’s understanding of brachial plexus birth injury
Authors: Goldsand Michelle , Lai Kathleen , Davidge Kristen , Ho Emily S.
Published: June 2023

Facilitating children’s understanding of their medical condition can improve health outcomes and psychosocial well-being. To inform how medical information is delivered, an interpretive qualitative approach was used to explore children’s understanding of their brachial plexus birth injury. In-depth interviews of children with brachial plexus birth injuries ( n = 8) and their caregivers ( n = 10) were conducted individually and as a child-caregiver dyad. Thematic analysis of interview data found that children primarily understood their injury through lived experiences of functional and psychosocial concerns related to movement and appearance of the affected limb, rather than medical information. Children’s ability to learn about diagnostic and prognostic information was influenced by age, emotional readiness, and background knowledge. In receiving information about their medical condition, children needed greater support in understanding their prognosis and its implications on their future. These narratives indicate the importance of addressing the primary functional and psychosocial concerns to contextualize medical information and ascertain the emotional readiness of children with brachial plexus birth injuries in information delivery approaches.
Dynamic modelling of deep groove ball bearings with different local defects considering skidding and thermal elastohydrodynamic lubrication
Authors: Tian Yu , Yan Changfeng , Liu Yaofeng , Kang Jianxiong , Lu Zunyou , Wu Lixiao
Published: June 2023

The vibration characteristics and skidding behaviour of deep groove ball bearings (DGBBs) are significantly influenced by the evolution of local defects and thermal effects. In previous studies, the influences of skidding and thermal effects were not considered in order to simplify the model of defective bearings. But the presence of skidding and thermal should not be ignored to accurately simulate the operation of bearing. To gain a comprehensive understanding of the operational mechanism of defective bearings, it is crucial to examine the skidding and thermal characteristics of various defect types using dynamic modelling approaches. In this study, the DGBB dynamic model for seven types of defects is established, which considers the self-rotation, rotation, and radial motion of ball, the contact force, ball/cage and ball/raceway skidding, and the effects of thermal elastohydrodynamic lubrication (TEHL). Experimental data from a machine fault simulator test rig is utilized to validate the accuracy of the proposed modelling methods. The results indicate that compound defects (CDs) result in higher vibration amplitudes and more severe skidding phenomena compared to single defects (SDs). Furthermore, compound defects exhibit a greater thermal effect on the oil film in the contact area than SDs, significantly impacting the operational performance of the bearing.
The electron beam freeform fabrication of NiTi shape memory alloys. Part II: Influence of the heat treatment on the superelastic behaviour
Authors: Guimarães RPM , Rauchdobler B , Pixner F , Mahdi A , Ferraz FMB , Poletti C , Enzinger N , Amancio-Filho ST
Published: June 2023

In a previous study (part I), the deposition of functional single-track and multi-layer Ni-rich NiTi using the electron beam freeform fabrication (EBF3) technique was demonstrated. The processed microstructure consists of columnar millimetre range grains that grow parallel to the build direction. Based on the same parameters of part I, this work successfully deposited a stable multi-track and multi-layer NiTi block. Different heat treatments were applied to modify the superelastic properties of the deposited material. Initially, the solution treatment reduces the chemical inhomogeneity and the thermal stresses that originated during the deposition and cooling. Subsequently, due to ageing, Ni4Ti3 particles precipitate at 350 °C and 450 °C for 1, 6 and 12 h, modified the superelastic behaviour of the deposited NiTi. The differential scanning calorimetry results did not reveal any difference in the martensitic starting temperature between as-built and solution-treated samples. However, a remarkable influence of the ageing temperature was detected: while ageing at 350 °C impacted R-phase starting temperatures, 450 °C altered the martensitic starting one. The superelastic behaviour was evaluated by cycling compression. As-built and solution heat-treated samples presented poor mechanical performance, with about 40% of strain recovered after 10 cycles. The ageing at 350 °C for 1 h led to a maximum measured strain recovery of 72.5% after 10 uniaxial compression cycles up to 860 MPa. This condition also resulted in 3.3% permanent deformation out of 11.3% of the total. This study addressed for the first time the fabrication by the EBF3 technique of a stable multi-track and multi-layer NiTi block besides the importance of heat treating it, demonstrating that this post-treatment improves the superelastic performance of EBF3 fabricated parts.
Performing political stories of the self: Subverting identities in the city of Goma, DR Congo
Authors: Kniknie Sam
Published: June 2023

Since the ‘performative turn’ in social sciences, ethnographers have extensively studied how performances both constitute the subject and method of social theory but rarely understood the political potential that lies in it for research participants. This article looks at how young urban activists in the city of Goma in the Democratic Republic of Congo (hereafter Congo) politically appropriated performances that were initially meant as a research tool. Using audiovisual methods, this article analyzes three musical performances that were part of collaborative ethnographic research with a political youth group in Goma’s urban periphery. The members of this group used songs produced during the research process to create new identities and subvert political labels applied to them by outsiders. While this political storytelling of the self is an imperfect process, it signifies how ethnographic knowledge is not simply representational but always (co-)produced and performative.
Don’t Give Me Lip: A Role for Lipid-Accumulated Reactive Astrocytes in Temporal Lobe Epilepsy
Authors: Rosenberg Evan C. , Goldberg Ethan M.
Published: June 2023

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A life for a lifetime: Hendrik D. Loock and the Tygerberg Children’s Choir
Authors: Lamprecht Dorathea Julia , van Niekerk Caroline
Published: June 2023

The Tygerberg Children’s Choir (TCC) is rooted in South Africa’s Afrikaner culture. Its transition to a multicultural children’s choir, within a drastically changed political dispensation, furnished a rich subject for a historiographic choir identity investigation. From its establishment in 1972 until 2019, Hendrik D. Loock was the conductor. Since then the choir has continued under Karina Erasmus. The TCC is one of the oldest existing mixed-gender regional children’s choirs in the country, directed by the longest serving conductor of such a choir. The choir’s identity and Loock’s forty-seven-year directorship are interwoven, his work perceived as a significant cultural contribution. With his late wife Theresa (TCC accompanist, choral trainer, and arranger of choir music for thirty-two years), Loock confirmed a uniquely familial leadership profile amongst children’s choirs. This qualitative biographic report about the life and contribution of Loock and the TCC merges thematically analysed data from the TCC’s archival collection, non-participant observations, face-to-face interviews, and contextual information.
“Amid the Wildflowers”: Jane Frazee - Her Life, Career, and Contributions to Music Education in the United States
Authors: Kupinski Erica
Published: June 2023

Jane Frazee, an American music educator, administrator, and author has contributed to music education in the United States. This article surveys the impact of her efforts from 1960 to 2015. A pioneer member and past president of the American Orff-Schulwerk Association (AOSA), she taught music to children and adults using the Orff approach and has presented at workshops, clinics, and conferences throughout the United States, as well as internationally. She authored several books and Orff arrangement collections, and her articles have been published in prestigious professional journals and other publications. This paper addresses Frazee’s early life, training, influential individuals, teaching of children and adults, and her work with AOSA. Her roles in the founding and administration of Orff certification and graduate programs in music education in Minnesota are discussed. Lastly, Frazee’s role as an author and the influences of her publications on music educators in the United States were also examined. Although retired from teaching and administration, Frazee continues to publish and inspires current and future generations of music educators.
Superhero Storytelling: the Law, Sovereignty and Time
Authors: Curtis Neal
Published: June 2023

In both Comics Studies and Cultural Legal Studies, questions about the relationship between superheroes and the law have most commonly been treated in terms of vigilantism or in relation to the concept of sovereignty. With regard to sovereignty, though, the tendency has been to explore the concept in relation to its fundamental spatial organisation. In this article, however, I would like to consider law and sovereignty in relation to time. In particular how they are linked to the regulation and control of stories that recount histories and with that determine how identities and the legal and normative frameworks that support them are imagined in the future. To do this the article firstly introduces the work of Robert Cover and his definition on nomos as a normative universe in which we dwell. To this I add the work of Scott Richard Lyons to talk about expressions of ‘rhetorical sovereignty’ in two superhero comics: Captain America: Truth: Red, White and Black, and Blue Marvel. These are read as examples of legal storytelling that seek to change the mode of public discourse; challenge dominant (racist) representations, and reset the debate in the search for and application of justice.
Humor and the Law: Laughter as Critique/The Limits of Laughter
Authors: Adriaensen Brigitte , Bricker Andrew Benjamin , Godioli Alberto , Laros Ted
Published: June 2023

In this introduction, we outline several approaches to the role humor might play in relation to the law through the six articles contributed to this special issue and through important and more recent theories that have guided discussions of humor. We take up two aspects in particular when addressing the efficacy of humor: its ability to serve as a diagnostic tool and even cure; and its weaknesses, limitations, and shortcomings. Finally, we outline the specific contributions this special issue makes to the study of humor and the law and some new directions for research into humor and the law around affect, ethics, aesthetics, and politics.