bluuebunny/crossref_metadata_2025 huggingface dataset:
EXPERTS II - How are patient and caregiver participation in health and social care shaped by experienced burden of treatment and social inequalities? Protocol for a qualitative synthesis.
Authors: May Carl R , Chew-Graham Carolyn A , Gallacher Katie I , Gravenhorst Katja C , Mair Frances S , Nolte Ellen , Richardson Alison
Published: June 2023

Background: The workload health and social care service users and caregivers take on, and their capacity to do this work is important. It may play a key part in shaping the implementation of innovations in health service delivery and organisation; the utilisation and satisfaction with services; and the outcomes of care. Previous research has often focused on experiences of a narrow range of long-term conditions, and on factors that shape adherence to self-care regimes. 

Aims: With the aim of deriving policy and practice implications for service redesign, this evidence synthesis will extend our understanding of service user and caregiver workload and capacity by comparing how they are revealed in qualitative studies of lived experience of three kinds of illness trajectories: long-term conditions associated with significant disability (Parkinson’s disease, schizophrenia); serious relapsing remitting disease (Inflammatory Bowel Disease, bipolar disorder); and rapidly progressing acute disease (brain cancer, early onset dementia). 

Methods: We will review and synthesise qualitative studies of lived experience of participation in health and social care that are shaped by interactions between experienced treatment burdens, social inequalities and illness trajectories. The review will involve: 

Construction of a theory-informed coding manual; systematic search of bibliographic databases to identify, screen and quality assess full-text papers. 

Analysis of papers using manual coding techniques, and text mining software; construction of taxonomies of service user and caregiver work and capacity. 

Designing a model of core components and identifying common factors across conditions, trajectories, and contexts. 

Work with practitioners, and a Patient and Public Involvement (PPI) group, to explore the validity of the models produced; to develop workload reduction strategies; and to consider person-centred service design. 

Dissemination: We will promote workload reduction models to support service users and caregivers and produce policy briefs and peer-reviewed publications for practitioners, policy-makers, and researchers.
Götunöfn í Reykjavík 2001-2022
Authors: Jakobsson Ármann , Kvaran Guðrún
Published: June 2023

Greinin fjallar um störf götunafnanefndar Reykjavíkur á árunum 2001 til 2022.
Að blóta á íslensku
Authors: Svavarsdóttir Ásta
Published: June 2023

Swearing in Icelandic is the topic of this article. The main focus is on the grammatical aspects of swear words, i.e. their morphological and syntactic characteristics and behaviour, emphasizing how one swears rather than why. The Tagged Icelandic Corpus (MÍM), containing searchable texts from the early 21st century, is the primary source for the analysis. Even if the vocabulary of swear words is relatively small and swearing is a formulaic use of language, the results show that there can be considerable flexibility in Icelandic swearing and that there are creative means to modify and extend both the vocabulary and the syntactic constructions typical of swearing. The vocabulary extensions are partly based on word-formation (in some cases with unusual methods) and partly by borrowing, especially from English nowadays. In the syntax, certain forms of nouns used in swearing have acquired new functions, e.g. by using them adverbially, and nominal phrases can be extended by adding attributes preceeding the head-noun, adding to their diversity and effect. In such phrases, the genitive forms of swear nouns ‒ usually preceeding the head counter to genitive attributes in other nominal phrases — have been reinterpreted as adjectives allowing them to be freely coordinated in a string of attributes without conjoining them by conjunctions.
Kviðristarinn í Kaupmannahöfn: Um raðmorð, íslenskt samfélag og skáldsöguna Kóperníku (2021) eftir Sölva Björn Sigurðsson
Authors: Ómarsson Marteinn
Published: June 2023

Þessi grein fjallar um raðmorðingja, einkum það hvernig gerendurnir birtast í sögum. Þá er glæpasagan Kóperníka (2021) eftir Sölva Björn Sigurðsson athuguð sérstaklega. Raðmorðingjafræði eru kynnt og afbrotahegðunin skoðuð út frá íslensku samfélagi og bókmenntum þar sem meðal annars er stuðst við skrif bandaríska félagsfræðingsins Kevin D. Haggerty. Enda þótt raðmorðinginn sé býsna áberandi sem persóna í ýmsum afurðum dægurmenningarinnar á Vesturlöndum er athæfið í raun mjög sjaldgæft. Engin dæmi eru um morð af þessu tagi á Íslandi síðan nútíminn hófst og getur það meðal annars stafað af smæð þjóðarinnar sem og félags- og menningarlegri samsetningu hennar. Íslenskir raðmorðingjar fyrirfinnast þó í innlendum bókmenntum og kvikmyndum en til þess að mæta raunsæiskröfu sagnagerðarinnar er vandkvæðum bundið að aðlaga þá að íslenskum veruleika. Sölvi Björn leysir þetta með því að flytja lesendur aftur til þess tíma þegar Kaupmannahöfn var höfuðstaður landsins, borg í örum vexti með tilheyrandi þensluverkjum, sjúkdómum og fátækt, og um leið tilvalinn vettvangur fyrir raðmorð. Í skáldsögunni á sér einnig stað úrvinnsla á einu þekktasta raðmorðmáli sögunnar, kviðristumorðunum í Lundúnum árið 1888, og er líka fjallað um þau í greininni og hvernig höfundur vinnur úr málinu í frásögn sinni.
Determining Tuffier’s Line by Ultrasound in Pregnant and Non-pregnant Female Patients: a prospective cohort study
Authors: Pırbudak Lutfiye , Seker Bahar , Mendes Ergun , Emelı Yusuf
Published: June 2023

Objectives: The correct determination of the vertebral level is important in anesthesia management and the prevention of possible risks. It has been shown that estimation of L4/5 intervertebral lumbar level based on Tuffier’s line determined by palpation (palpated L4/5) is often inaccurate. In this study, it was aimed to investigate how Tuffier’s line changes in the lateral decubitus position due to pregnancy.
Material and Methods: The patients were divided into two groups in this prospective cohort study. The pregnant patients were assigned to Group P (n = 75) while the non-pregnant patients were assigned to Group NP (n = 60). Lumbar ultrasound was conducted in both groups in the left lateral decubitus position to verify the vertebral level determined by Tuffier’s line that was detected by palpation. Demographic data, determination time of Tuffier’s line, ultrasound, and the detected vertebral levels were recorded in both groups.
Results and Discussion: Vertebral levels detected by both techniques were compatible with 35 (46.6%) patients in Group P and 36 (60%) patients in Group NP (p = 0.165). The vertebral levels in Group P detected via ultrasound were determined at L2 in three (4%) patients, at L2/3 in three (4%) patients, at L3 intervals in three (4%) patients, and at the L3/4 interval in 31 (41.3%) patients. The vertebral levels of the patients in Group NP detected via ultrasound was at L2/3 in 2 (3.3%) patients, and at the L3/4 interval in 22 (36.7%) patients. For the risk of insertion from a risky injection site, the OR = 3.96–95 and GA = 0.82–19.05 in Group P were higher compared to Group NP (approximately 4 times higher). While Group P was significantly limited in the risk analysis, according to L3 (p = 0.087), the risk under this level was similar (p = 0.124). In this study, the verification of Tuffier’s line determined through palpation did not show the correct vertebral level in almost half of the patients in the lateral decubitus position, regardless of pregnancy and demographic data.
Conclusion: We believe a possible spinal cord injury can be prevented by determining the needle insertion site via lumbar ultrasound in the pregnant patients.
Bangladesh Journal of Medical Science Vol. 22 No. 03 July’23 Page : 529-535
Development of gamification as addiction education and examining its effects on students’ motivation and enjoyment
Authors: Mosalanejad Leili , Mansouri Erfan
Published: June 2023

Introduction Addiction is a “social disease” which has physical and mental effects. Having adequate knowledge and information about addiction is the best way to prevent it in the community. The current study aims to focus on developing gamification as addiction education and examining its effects on students’ motivation and enjoyment.
Methods: This is guise experiment for gamification development and assess educational intervention. Educational and technical standards have been considered for the development of gamification. In technical standards, it is congruent with the app-making technology based on dynamism, mechanisms and dynamic gamification. This game is available on www.addiplay.ir website through Microsoft Aps net core technology. Educational intervention implied on two groups of medical students and Public Health students and learning indicators assessed through intervention.
Results; The findings of this study on two groups of students showed that, the game can influence on students’ enjoyment and consent. In addition, the game had a high average in increasing learners’ ability and students satisfaction. One of the limitations of gamification has been its dependence on each learner’s ability.
Conclusion: The results showed that new teaching and learning methods such as gamification in addiction lessons in a mixed and complimentary way can fulfill the educational goals instead of written handbooks or traditional classes and makes learning possible in a motivated and entertaining environment.
Bangladesh Journal of Medical Science Vol. 22 No. 03 July’23 Page : 564-572
IVF Children Acquiring Emirati Citizenship by the Nationality of a Parent (Jus Sanguinis)
Authors: Enizi Ziad Al , Mahameed Waleed Fouad
Published: June 2023

Objective. The technology of in vitro fertilization (IVF) opened a new era in the treatment of infertility but at the same time it created new challenges for civil and international private law. This concerns the issues of determining and/or acquiring child citizenship and legal conflicts associated with this.

Materials and methods. This study examines the aspects of obtaining UAE citizenship through the study of the UAE Citizenship Law and the principle of jus sanguinis (right of blood) when citizenship is acquired by a parent’s nationality. The research aims to identify whether the current legislative regulation of the UAE meets the current challenges in the field of family relations against the backdrop of new medical advances in IVF. The paper considers the aspects of the UAE legal regulation in the scope of family law relationships. The above issues were considered from the critical evaluation prospects taking into account the potential ways for their improvement.

Results and Discussion. The problems associated with determining the citizenship for those born as a result of IVF are the subject of discussion, while, as practice shows, the law often does not keep pace with the development of reproductive technologies. Based on the analysis of legal regulation and practice, the study summarizes the grounds for obtaining UAE citizenship by children conceived through IVF and refusals to obtain it.

Conclusion. The paper recommends mitigating the requirement of proof of paternity as a condition to grant the nationality to an IVF child, especially in the case of purely medical errors in which father has no responsibility.

Bangladesh Journal of Medical Science Vol. 22 No. 03 July’23 Page : 676-686
Study on the Diversity of Genotypic Varieties of Durum Wheat (Triticum Durum Desf.) In the Sub-Humid Region of El Harrouch, Algeria
Authors: Bourouh LN , Souilah N , Boulacel M , Bendif H , Chaib G , Hazmoune T
Published: June 2023

The study on the yield parameters and the morpho-biometric characterization of twenty genotypic varieties of durum wheat (Triticum durum Desf.) was carried out in the sub-humid region of El Harrouch of Algeria. A descriptive sheet according to the recommendations of UPOV (2014-2017) and the calculation of the Shannon and Weaver diversity index was prepared with 27 qualitative characters and one quantitative character relating to the different parts of the ear. The yield parameters, such as number of plants/m2, herbaceous tillers, ear tillers, number of ears/m2, number of grains/ear, weight of 1000 grains, grains yield, harvest index, areal biomass, economic yield and straw yield showed a great diversity among these varieties. The Shannon and Weaver index (H') revealed a great diversity of all the studied genotypes (H'=0.52). The high polymorphic characters were the shape of the shoulder of the lower glume (H'=1), the curvature of the beak of the lower glume (H'=0.9), the length of the rachis of the ear (H'=0.87), the disposition barbs (H'=0.86), the length of the hairs of the grain brush (H'=0.84), the hairiness of the first article of the rachis of the ear (H'=0.84) and the length of the first article of the ear (H'=0.81). Based on study result, the varieties suitable to this agro-ecological conditions could be chosen for this region. It is concluded that the creation of descriptive sheets, the knowledge of production and adaptation parameters could be considered as precursors of high yield for economic needs and mastery of production techniques in improvement programs.
J. Biodivers. Conserv. Bioresour. Manag. 2023, 9(1): 41-60
Performance and Nutrient Content of Okra (Abelmoschus Esculentus L. Moench) Fruits as Influenced by Vermicompost, Nitrogen and Zinc Grown in Soil
Authors: Prity NN , Syed M , Rahman MK
Published: June 2023

This investigation aimed to assess the influence of soil-applied vermicompost, nitrogen and zinc on the vegetative growth parameters, yield, and mineral nutrient concentration of the fruits of okra (Abelmoschus esculentus L. Moench). The experiment was laid out in a Completely Randomized Design followed by three replications. Data were subjected to analysis of variance and mean values were compared using Tukey’s Range Test at p ≤ 0.05. Variation in mean values was compared among eight treatments: control (T1), 6 ton ha-1 vermicompost (T2), 60 kg ha-1 N (T3), 2 kg ha-1 Zn (T4), 6 ton ha-1 vermicompost + 60 kg ha-1 N (T5), 60 kg ha-1 N + 2 kg ha-1 Zn (T6), 6 ton ha-1 vermicompost + 2 kg ha-1 Zn (T7), and 6 ton ha-1 vermicompost + 60 kg ha-1 N + 2 kg ha-1 Zn (T8). The maximum growth performance and yield contributing properties of okra, viz. plant height (56 cm), leaf number (11 plant-1), leaf area (14.5 cm2), stem girth (3.5 cm), branch number (8 plant-1), and fruit number (6.50 plant-1), fruit diameter (5.50 cm), fruit length (13.50 cm), and weight of fresh (64.29 g) and dry plant materials (14.56 g), were found in T5. The control T1 performance showed reducing trends compared to other treatments. Although there was no significant difference with the application of vermicompost 6 t ha-1 + N 60 kg ha-1 + Zn 2 kg ha-1 (T8), the treated pot in vermicompost with 6 t ha-1 + N 60 kg ha-1 (T5) showed the best achievements of macro elements N (0.008%), P (6.70 ppm), K (0.08 cmol/kg), and S (18.22 ppm) of post-harvest soil compared to the control T1. Mineral nutrients of fruits N-1.64%, P-0.27%, K-0.30%, S-0.10%, and Fe-0.02% and protein content 10.23% were found to be highest in the identical T5 where Zn content was highest (0.28%) in T8. This study showed that the treatment of vermicompost with 6 t ha-1 + N 60 kg ha-1 (T5) contained and released quality nutrients is recommended for its overall best growth performance for okra.
J. Biodivers. Conserv. Bioresour. Manag. 2023, 9(1): 101-108
Shifting Career Aspirations and Anxiety During The Covid-19 Pandemic
Authors: Teguh Akbari Taufan , Faisal Muhammad
Published: June 2023

The COVID-19 pandemic has caused changes in young people, especially in the mental health and career aspect. The existence of COVID-19 worsens their mental health condition. Various factors make a person experience symptoms of anxiety or depression. In addition to mental health, COVID-19 has affected young people's perception of careers. The question is how far the pandemic has caused personality change in young people and affected career preferences. Therefore, this study has two objectives: understanding the intrapersonal and interpersonal changes in young people groups and what stakeholders should do about these changes. This research uses a quantitative approach with a survey method. A total of 1.036 young people participated in the survey. This study indicates that although young people feel anxious, worried, and afraid, they still adapt, as evidenced by the emergence of new hobbies and abilities. In addition, young people are also optimistic about their career preferences and believe that they can overcome the COVID-19 pandemic. However, this optimism will not last if the pandemic continues the following year. This research requires all stakeholders to formulate appropriate ways to mitigate young people's mental health problems.
Explaining Parent-Child Relationship During The Covid-19 Pandemic in Semarang City
Authors: Fatmasari Agustin Erna , Fatimah Nurhayati Niken
Published: June 2023

The relationship with parents is one source of happiness and psychological well-being for children. The impact of the relationship is undoubtedly essential for children in dealing with rapid changes, such as the COVID-19 pandemic. This study aims to explain the parent-child relationship during the COVID-19 pandemic in Semarang. The method used in this study is indigenous psychology with a grounded theory approach. The data retrieval technique used is purposive sampling by filling out the open-ended questionnaire. A total of 207 emerging adult children aged 17-23 suitable for the inclusion criteria were willing to participate in this study. The study found that the parent-child relationship was getting closer during the COVID-19 pandemic in Semarang for respondents who were close before the pandemic. However, there has been no change in parents and children who have a distant relationship since before the pandemic. This study also indicates that communication, giving support, father’s character, togetherness, loving, and thinking of fathers as role models are forms of the father-child relationship. Moreover, the forms with their mothers are indicated by the communication, loving, togetherness, mother’s character, and giving support.
Comparison of Muscle Activation During Toes to Bar Movement Performed with Different Techniques
Authors: Aydın Erbil Murat , Gündoğan Burak , Demirkan Erkan
Published: June 2023

With the increasing importance of physical fitness in the world, physical activity types such as CrossFit, which includes high-intensity combined movements, have become popular. The aim of this study was to compare the rectus abdominis (RA) muscle activation during the kipping toes-to-bar (KTB) and the strict toes-to-bar (STB) movements. RA muscle activation was measured during the KTB and STB exercises in 12 healthy young men. Participants performed 5 repetitions of both KTB and STB exercises in randomized order. Participants performed both exercises with a 5-minute rest interval. For comparing the RA muscle activity during the KTB and STB paired sample t-test was used. A significant difference was found between the KTB (359.56 ± 160.50 μV) and the STB (415.37 ± 185.63 μV) for RA muscle activation (p<0.05). These findings demonstrated that the difference in RA muscle activity during the STB and KTB movements showcases the importance of the STB movement on the RA that revealed greater motor units’ activation in a non-oscillation position. The study finding emerges that the same exercise can lead to different motor unit activations in the same muscle group, depending on the way the movement is performed.
Bakır(II)–Sulfametazin-2,2'-bipiridin Kompleksinin Hesaplamalı Kimya Yöntemi ile Spektroskopik Özelliklerinin İncelenmesi: Moleküler Modelleme Çalışması, ADME/T
Authors: ÖZTÜRK Filiz , AYCAN Tuğba
Published: June 2023

[Cu(smz)2bipy] kompleksinin teorik hesaplamaları DFT (Yoğunluk Fonksiyonel Teorisi) yöntemi ile B3LYP ve LanL2DZ baz seti kullanılarak hesaplanmıştır. Hesaplamalar sonucunda elde edilen değerler, deneysel yapının geometrik parametreleri ile oldukça uyumludur. Bununla birlikte sulfamethazin ligantının DFT/B3LYP/6-311G baz seti kullanılarak hesaplanmıştır ve sonuçlar kompleks yapı ile karşılaştırılmıştır. Kompleks optimize edildikten sonra EHOMO ve ELUMO değerleri saptanmıştır. Sınır Moleküler Orbitalleri (FMOs) ile kompleks ve serbest ligant (Hsmz)’nin kimyasal ve biyolojik aktiviteleri karşılaştırılmıştır. Mulliken popülasyon analizi, MEP (Moleküler Elektrostatik Potansiyel) ve MEP kontör gösterimi ile kompleksin elektrofilik ve nükleofilik bölgeleri belirlenmiştir. Kompleksin ve Hsmz ligantının deneysel IR (Infrared) sonuçları teorik olarak elde edilen değerler ile karşılaştırılmıştır. Hirshfeld yüzey analizi yöntemi ile moleküller arası etkileşimleri ayrıntılı incelenmiştir. Ayrıca E. coli bakterisi üzerinde olumlu sonuçlar verdiği dikkate alınarak PDB (Protein Data Bank)’dan Giraz Tip IIA Topoisomeraz ve DNA Giraz enzimleri indirilerek moleküler kenetleme çalışması yapılmıştır. Kompleks, in-silico yöntem ile ADME/T özellikleri incelenerek ilaç özelliği taşıyıp taşımadığı tartışılmıştır.
Worms: Primordial Juris-prudence and Viral Being
Authors: Gearey Adam
Published: June 2023

The pandemic provokes a radical thinking of jurisprudence. Drawing on Heidegger’s Being and Time, this paper puts forward an argument for primordial analysis. Human being is inescapably bound to viral infection. Juris-prudence is primordially the ‘seeing’ of iuris: that which binds or obligates. Prudence is the projection forward from the condition of being bound. Viral being can be seized by Dasein as a resolute response to common suffering. Dasein’s resolute response enables the fundamental link to be made between Heidegger’s notion of conscience and the primordial meaning of hospital. Primordial juris-prudence thus seeks the ontological articulation of a mode of public responsibility or solidarity for the burden borne by Dasein.
The Struggle to Breathe: Pandemic Years on Western Frontiers
Authors: Javidan Pantea
Published: June 2023

Multiple existential threats – climate breakdown, disease, police violence, lawlessness, trauma, and systemic harms – characterise the pandemic years on western frontiers. This essay considers these and argues that disaster capitalism and authoritarian politics overpower scientific consensus and public opinion in ways that literally and figuratively cause a struggle to breathe.
‘Is there an Eternal Return of HIV / AIDS-related Discrimination?’: Law Reform in the Karmic Machines of Time and Becoming
Authors: Man-chung Chiu
Published: June 2023

The laws controlling HIV / AIDS in Mainland China, Taiwan and Hong Kong have adopted very different policy orientations. The article argues that, while the differences in laws manufacture different impacts on the level of discrimination against PLHAs, they all, in one way or another, fixate themselves on the past imaginary in relation to HIV / AIDS, and ignore the emerging future (for example: advanced medical technology); they do this so as to avoid revising the current laws, thus sustaining or intensifying the existing discrimination. The article, via investigating the respective time machines devised by Nāgārjuna, Nietzsche and Deleuze, attempts to suggests that future, present and past all exist and inter-influence each other in a singular mental dimension. The article also scrutinizes the role of law and possible law reform in re-formatting the time machine and redefining disease control.
The Common Meat: Culinary Capital, Food Privilege, and Waste in Starve
Authors: Marini Anna Marta
Published: June 2023

Written by Brian Wood with art by Danijel Žeželj and Dave Stewart, Starve (Image 2015–2016) is a comic book revolving around the comeback of self-exiled celebrity chef Gavin Cruikshank. His food travelling TV show has been turned into a culinary sport arena in which renowned chefs battle for the entertainment of the super-rich 1% of the world’s population, cooking with rare ingredients whose consumption is illegal or regulated due to extinction. Caught in a conflict with the TV network and his ex-wife, Cruikshank is sickened by the very essence of the reality show, serving only to feed the expectations of opulence, decadence, and exclusivity of the privileged audience. The comic tackles issues related to waste and abuse of food sources, while denouncing the nature of the gourmet food industry. By showing Cruikshank’s navigation through the show and his consequent boycott, Starve lays bare the mechanisms of an industry in which chefs are bound to produce transgressive novelty, whether procuring the meat of animals on the brink of extinction or transforming “common meat” into refined bites that can indulge the privileged palate. Social power asymmetries are exposed to appalling effect, as the mediated context glamourizes the otherwise “distasteful” handling of animal bodies that is assumed as reserved for kitchen peons and the lower classes. In the dystopic yet realistic universe described in Starve, culinary capital is key to inequality, but also a means of empowerment against food insecurity. Cruikshank’s aim to create a network of food businesses rooted in their neighborhood and the optimization of the available resources embodies the possibility to revert food deserts, counterbalancing the mechanisms of the gourmet industry.
Isıl işlem uygulanmış karbon fiber ile güçlendirilmiş lamine kaplama kerestenin (LVL) hava kurusu yoğunluk ve liflere paralel basınç direncinin belirlenmesi
Authors: PERÇİN Osman
Published: June 2023

Isıl işlem, kimyasal madde kullanılmadan ağaç malzemenin bazı özelliklerinin iyileştirilmesi için geliştirilen çevre dostu bir odun modifikasyon yöntemidir ve son yıllarda Avrupa ve Dünya’da yaygın olarak kullanılmaya başlanmıştır. Isıl işlem, ahşap malzemede denge rutubet miktarını azaltmakta, boyutsal stabilizasyonu ve biyolojik direnci önemli derecede de artırmaktadır. Bu çalışma, ısıl işlem uygulanmış ahşap malzemelerden farklı tutkallarla yapıştırılarak ve karbon fiber kumaş ile güçlendirilerek üretilen lamine kaplama kerestelerin (LVL) hava kurusu yoğunluk ve liflere paralel basınç direnci değerlerindeki değişimlerin belirlenmesi amacıyla yapılmıştır. Bu maksatla karaçam (Pinus nigra) ahşap malzemeler, 150, 175 ve 200 °C’de 2 saat ısıl işlem uygulandıktan sonra uygun boyutlarda kesilmiş, poliüretan (PU) ve polivinil asetat (PVAc) tutkalları kullanılarak lamine edilmiştir. Lamine kompozit malzemenin özelliklerini iyileştirmek için ahşap kaplamalar arasına takviye tabakası olarak karbon fiberler eklenmiştir. Test sonuçları ısıl işlemin, hava kurusu yoğunluk değerleri ve liflere paralel basınç direncini azalttığını göstermiştir. Öte yandan güçlendirme işlemi hava kurusu yoğunluk ve liflere paralel basınç direncinin ikisini de artırmıştır.
Sipariş Tipi Üretim Yapan Orta Ölçekli Mobilya İşletmelerinde Makine Seçimi
Authors: KUŞCUOĞLU Mehmet Özgür , DİLİK Tuncer
Published: June 2023

Çalışmada, sipariş tipi üretim yapan orta ölçekli mobilya işletmeler için makine seçimi konusu incelenmiştir. Ülkemiz mobilya endüstrisinin sektörel olarak yakalamış olduğu gelişimle birlikte işletmelerin sahip olduğu makine hatları ve yatırımları göz önüne alındığında genel olarak kapasite kullanım oranının beklenilenin altında olduğu görülmektedir. Mevcut duruma kalifiye makine operatörlerinin de eksikliği eklendiğinde, rasyonel bir yatırım ve üretim için doğru makine seçiminin önemi açıkça ortaya çıkmaktadır. Araştırmada, sipariş tipi üretim yapan orta kapasiteli panel mobilya üreticileri için makine seçimi incelenmiştir. Bu amaçla, panel mobilya imalatının önemli üç temel üretim prosesi (ebatlama, kenar bantlama ve delik delme işlemleri) için CNC, PLC kontrollü veya konvansiyonel olmasına bakılmaksızın makine tipinin seçimi yapılmıştır. Çalışmada yöntem olarak çok kriterli karar verme yöntemlerinden biri olan AHP (Analitik Hiyerarşi Süreci) yöntemi kullanılmıştır. Sonuç olarak, orta ölçekli mobilya işletmeleri için, incelenen üretim proseslerine yönelik uygun bir makine veya makine tipi kombinasyonları seçilerek, rasyonel bir yatırım ve optimum kapasite kullanım oranlarına ulaşılabileceği önerisi getirilmeye çalışılmıştır.
Increasing Satisfaction and Repurchase Intention on Contemporary Food and Beverages Through E-commerce
Authors: Subekti Rini , Viana Praningtyas Elisabeth Ria , Anggya Anggraini Putu Ayu
Published: June 2023

This study aims to analyze consumption behavior using 2 categories of consumer behavior, namely utilitarian shopping value and hedonic shopping value. Utilitarian shopping value and hedonic shopping value to increase satisfaction and repurchase intention in the contemporary food and beverage business through e-commerce. Nowadays, food and drink are not only basic needs but also a part of a lifestyle. The food industry is currently growing rapidly. According to data from the Ministry of Industry, the food and beverage industry is one of the important sectors that supports the performance of the non-oil and gas processing industry. In addition, the food and beverage industry is one of the sectors that receive development priorities according to the Making Indonesia 4.0 roadmap. Food and beverage products in great demand are various processed drinks made from coffee or tea, korean snacks, and others. These food and beverage products are also easy to obtain by purchasing online. Therefore, this condition becomes something interesting to observe, especially on consumer behavior. This research is quantitative analsys. This research using SEM PLS. The result of this study shows that hedonic shopping value, utilitarian shopping value, and satisfaction influences repurchase intention on an online contemporary foods and beverages. The biggest influence on the repurchase intention of contemporary food and beverages is hedonic shopping value. This study develops previous research, but in this study, it covers many food and beverage products. Respondents in this study were also from all over Indonesia.
СИНОДИКИ КОСТРОМСКОГО БОГОЯВЛЕНСКОГО МОНАСТЫРЯ
Authors: Романов Григорий Александрович
Published: June 2023

В статье исследуются три литературных памятника конца XVI – XVII в., происходящих из Костромского Богоявленского монастыря. Синодики-помянники служили народными книгами. Синодик конца XVI – начала XVII в. сохранил автограф писаря Горемыкина и имена убиенных в разные годы в Смутное время. Оба Синодика-помянника содержат имя основателя обители святого Никиты Костромского, имена святителей, окормлявших Костромской край, имена представителей княжеских, дворянских и купеческих родов. В Синодике XVII в. в числе родов вкладчиков монастыря поминается род Смоленского архиепископа Паисия Сарафанова, неизвестного по другим источникам. Сравнение имен игуменов и архимандритов из двух Синодиков со списками, составленными в XIX в. П. М. Строевым, выявили новые имена настоятелей Костромских обителей. Кормовой синодик зачитывали на службе и в трапезной на кормовых панихидах с поминовением рода вкладчика. В XVII в. в монастыре ежегодно совершали 214 именных панихид, 6 особых и 4 царские.

The article examines three literary monuments of the late 16th – 17th centuries, originating from the Kostroma Epiphany Monastery. Synodic commemorators served as folk books. Synodikon of the late 16th – early 17th century. preserved the autograph of the clerk Goremykin and the names of those killed in different years during the Time of Troubles. Both Synodic commemorators contain the name of the founder of the monastery, St. Nikita of Kostroma, the names of the saints who nourished the Kostroma Territory, the names of representatives of princely, noble and merchant families. In the Synodikon of the 17th century. among the genera of the contributors to the monastery, the family of Smolensk Archbishop Paisius Sarafanov, who is not known from other sources, is commemorated. Comparison of the names of abbots and archimandrites from two Synodicons with lists compiled in the 19th century. P. M. Stroev, revealed the new names of the abbots of the Kostroma monasteries. The stern synodic was read out at the service and in the refectory at stern memorial services with a commemoration of the family of the contributor. In the 17th century 214 memorial services were performed annually in the monastery, 6 special and 4 royal.
ЛОГИКА ФОРМИРОВАНИЯ НАРОДНО-ЦЕРКОВНЫХ ОБЫЧАЕВ: ЧИН ПАНАГИИ В СОВРЕМЕННОМ ПОМИНАНИИ СОРОКОВОГО ДНЯ (РОССИЙСКО-БЕЛОРУССКО-УКРАИНСКОЕ ПОГРАНИЧЬЕ)
Authors: Листова Татьяна Александровна
Published: June 2023

Основная религия восточных славян – православие – всегда функционировала на разных уровнях: каноническое церковное служение, церковные и народно-церковные обычаи и внецерковная религиозная практика. Их корреляция актуализировалась в разной степени интенсивности и взаимовлияния, результатом чего становились новые формы религиозных обычаев и ритуалистики. Данное соотношение сохранялось в советское время, сохранив свое значение в наше время. Репрезентативным примером взаимодействия Церкви и мирской религиозности является обычай поминания на 40-й день после смерти, соединяющий канонический чин панагии с народной интерпретацией христианской идеи ухода в этот день души умершего.

The main religion of the Eastern Slavs – Orthodoxy has always functioned at different levels: canonical church ministry, ecclesiastical and folk-church customs and extra-ecclesiastical religious practice. Their correlation was actualized in varying degrees of intensity and mutual influence, resulting in new forms of religious customs and ritualism. This ratio was maintained in Soviet times, retaining its significance in our time. A representative example of the interaction of the church and secular religiosity is the custom of commemoration on the 40th day after death, combining the canonical ceremony of lifting panagia with the popular interpretation of the Christian idea of the departure of the soul of the deceased on this day.
Prognostic Role of CD68+ and CD163+ Tumour-Associated Macrophages and PD-L1 Expression in Oral Squamous Cell Carcinoma: A Meta-Analysis
Authors: Chohan Mohammed Haseeb , Perry Matthew , Laurance-Young Paul , Salih Vehid M. , Foey Andrew D.
Published: June 2023

Background: Oral squamous cell carcinoma (OSCC) is a common malignant cancer in humans. An abundance of tumour associated macrophages (TAMs) create an immunosuppressive tumour microenvironment (TME). TAM markers (CD163 and CD68) are seen to serve as prognostic factors in OSCC. PD-L1 has seen to widely modulate the TME but its prognostic significance remains controversial. The aim of this meta-analysis is to evaluate the prognostic role of CD163+, CD68+ TAMs and PD-L1 in OSCC patients.

Methods: Searches in PubMed, Scopus and Web of Science were performed; 12 studies were included in this meta-analysis. Quality assessment of included studies was performed according to REMARK guidelines. Risk of bias across studies was investigated according to the rate of heterogeneity. Meta-analysis was performed to investigate the association of all three biomarkers with overall survival (OS).

Results: High expression of CD163+ TAMs were associated with poor overall survival (HR = 2.64; 95% Cl: [1.65, 4.23]; p < 0.0001). Additionally, high stromal expression of CD163+ TAMs correlated with poor overall survival (HR = 3.56; 95% Cl: [2.33, 5.44]; p < 0.00001). Conversely, high CD68 and PD-L1 expression was not associated with overall survival (HR = 1.26; 95% Cl: [0.76, 2.07]; p = 0.37) (HR = 0.64; 95% Cl: [0.35, 1.18]; p = 0.15).

Conclusion: In conclusion, our findings indicate CD163+ can provide prognostic utility in OSCC. However, our data suggests CD68+ TAMs were not associated with any prognostic relevance in OSCC patients, whereas PD-L1 expression may prove to be a differential prognostic marker dependent on tumour location and stage of progression.
A comparative recognition research on excretory organism in medical applications using artificial neural networks
Authors: Selvarajan Shitharth , Manoharan Hariprasath , Iwendi Celestine , Alsowail Rakan A. , Pandiaraj Saravanan
Published: June 2023

Purpose: In the contemporary era, a significant number of individuals encounter various health issues, including digestive system ailments, even during their advanced years. The major purpose of this study is based on certain observations that are made in internal digestive systems in order to prevent severe cause that usually occurs in elderly people.

Approach: To solve the purpose of the proposed method the proposed system is introduced with advanced features and parametric monitoring system that are based on wireless sensor setups. The parametric monitoring system is integrated with neural network where certain control actions are taken to prevent gastrointestinal activities at reduced data loss.

Results: The outcome of the combined process is examined based on four different cases that is designed based on analytical model where control parameters and weight establishments are also determined. As the internal digestive system is monitored the data loss that is present with wireless sensor network must be reduced and proposed approach prevents such data loss with an optimized value of 1.39%.

Conclusion: Parametric cases were conducted to evaluate the efficacy of neural networks. The findings indicate a significantly higher effectiveness rate of approximately 68% when compared to the control cases.
A conserved epitope in VAR2CSA is targeted by a cross-reactive antibody originating from Plasmodium vivax Duffy binding protein
Authors: Iyamu Uwa , Vinals Daniel Ferrer , Tornyigah Bernard , Arango Eliana , Bhat Rakesh , Adra Trixie Rae , Grewal Simranjit , Martin Kimberly , Maestre Amanda , Overduin Michael , Hazes Bart , Yanow Stephanie K.
Published: June 2023

During Plasmodium falciparum infection in pregnancy, VAR2CSA is expressed on the surface of infected erythrocytes (IEs) and mediates their sequestration in the placenta. As a result, antibodies to VAR2CSA are largely restricted to women who were infected during pregnancy. However, we discovered that VAR2CSA antibodies can also be elicited by P. vivax Duffy binding protein (PvDBP). We proposed that infection with P. vivax in non-pregnant individuals can generate antibodies that cross-react with VAR2CSA. To better understand the specificity of these antibodies, we took advantage of a mouse monoclonal antibody (3D10) raised against PvDBP that cross-reacts with VAR2CSA and identified the epitopes targeted by this antibody. We screened two peptide arrays that span the ectodomain of VAR2CSA from the FCR3 and NF54 alleles. Based on the top epitope recognized by 3D10, we designed a 34-amino acid synthetic peptide, which we call CRP1, that maps to a highly conserved region in DBL3X. Specific lysine residues are critical for 3D10 recognition, and these same amino acids are within a previously defined chondroitin sulfate A (CSA) binding site in DBL3X. We showed by isothermal titration calorimetry that the CRP1 peptide can bind directly to CSA, and antibodies to CRP1 raised in rats significantly blocked the binding of IEs to CSA in vitro. In our Colombian cohorts of pregnant and non-pregnant individuals, at least 45% were seroreactive to CRP1. Antibody reactivities to CRP1 and the 3D10 natural epitope in PvDBP region II, subdomain 1 (SD1), were strongly correlated in both cohorts. These findings suggest that antibodies arising from PvDBP may cross-react with VAR2CSA through the epitope in CRP1 and that CRP1 could be a potential vaccine candidate to target a distinct CSA binding site in VAR2CSA.
Exploring the selectivity and engineering potential of an NRPS condensation domain involved in the biosynthesis of the thermophilic siderophore fuscachelin
Authors: Ho Y. T. Candace , Izoré Thierry , Kaczmarski Joe A. , Marschall Edward , Ratnayake Minuri S. , Tailhades Julien , Steer David L. , Schittenhelm Ralf B. , Tosin Manuela , Jackson Colin J. , Cryle Max J.
Published: June 2023

In nonribosomal peptide synthesis, condensation (C) domains are key catalytic domains that most commonly link carrier protein bound substrates to form peptides or depsipeptides. While adenylation domains have been well characterized due to their role in the selection of monomers and hence as gate keepers in nonribosomal peptide biosynthesis, C-domains have been the subject of debate as they do not have apparent “A-domain like” side chain selectivity for their acceptor substrates. To probe the selectivity and specificity of C-domains, here we report our biochemical and structural characterization of the C3-domain from the biosynthesis of the siderophore fusachelin. Our results show that this C-domain is not broadly flexible for monomers bearing significantly alternated side chains or backbones, which suggests there can be a need to consider C-domain specificity for acceptor substrates when undertaking NRPS engineering.
Zero fluoroscopy catheter ablation for atrial fibrillation: a systematic review and meta-analysis
Authors: Debreceni Dorottya , Janosi Kristof , Bocz Botond , Turcsan Marton , Lukacs Reka , Simor Tamas , Antolič Bor , Vamos Mate , Komocsi Andras , Kupo Peter
Published: June 2023

Introduction

Catheter ablation for atrial fibrillation (AF) is the most frequently performed cardiac ablation procedure worldwide. The majority of ablations can now be performed safely with minimal radiation exposure or even without the use of fluoroscopy, thanks to advances in 3-dimensional electroanatomical mapping systems and/or intracardiac echocardiography. The aim of this study was to conduct a meta-analysis to compare the effectiveness of zero fluoroscopy (ZF) versus non-zero fluoroscopy (NZF) strategies for AF ablation procedures.

Methods

Electronic databases were searched and systematically reviewed for studies comparing procedural parameters and outcomes of ZF vs. NZF approaches in patients undergoing catheter ablation for AF. We used a random-effects model to derive the mean difference (MD) and risk ratios (RR) with a 95% confidence interval (CI).

Results

Our meta-analysis included seven studies comprising 1,593 patients. The ZF approach was found to be feasible in 95.1% of patients. Compared to the NZF approach, the ZF approach significantly reduced procedure time [mean difference (MD): −9.11 min (95% CI: −12.93 to −5.30 min; p < 0.01)], fluoroscopy time [MD: −5.21 min (95% CI: −5.51 to −4.91 min; p < 0.01)], and fluoroscopy dose [MD: −3.96 mGy (95% CI: −4.27 to −3.64; p < 0.01)]. However, there was no significant difference between the two groups in terms of total ablation time [MD: −104.26 s (95% CI: −183.37 to −25.14; p = 0.12)]. Furthermore, there was no significant difference in the acute [risk ratio (RR): 1.01, 95% CI: 1.00–1.02; p = 0.72] and long-term success rates (RR: 0.96, 95% CI: 0.90–1.03; p = 0.56) between the ZF and NZF methods. The complication rate was 2.76% in the entire study population and did not differ between the groups (RR: 0.94, 95% CI: 0.41–2.15; p = 0.89).

Conclusion

The ZF approach is a feasible method for AF ablation procedures. It significantly reduces procedure time and radiation exposure without compromising the acute and long-term success rates or complication rates.
EdTech in humanitarian contexts: whose evidence base?
Authors: Moser-Mercer Barbara , AlMousa Kawkab K. , Alhaj Hussein Rawan M. , AlSbihe Rawan K. , AlGasem Ahmad S. , Hadmoun Ali A. , Bakkar Bashar A. , AlQadri Mohammed H. , AlHmoud Mohammed M.
Published: June 2023

This study reports on the design and development of a methodological toolbox prototype for evaluating EdTech deployed in the contexts of fragility and crisis. The project adopted a bottom-up approach: training EdTech users in participatory action research approaches was followed by a comprehensive mapping of problems in the Azraq refugee camp that might be addressed through the chosen EdTech installed in a local Makerspace. Students as researchers used a developmental evaluation approach to deepen their understanding of evaluation as a concept and as a process and proceeded to match the results of their Azraq camp problem-tree analysis with evaluation questions related to the EdTech tools available in the Makerspace. The study concludes with a proposed methodological toolbox prototype, a set of approaches and processes that include research capacity building in fragile contexts, and user-led evaluation that emphasizes the notion of evaluation as a learning process driven by those designed to benefit from EdTech in fragile contexts.
The influence of ready-made tools on students’ learning by modelling with differential equations systems
Authors: Andresen Mette Susanne
Published: June 2023

This article discusses the role played by the tool when students learn about differential equations systems (DE) by modelling. The discussion was based on a three-case sub-study of an ongoing study of group-reports from experienced mathematics teachers participating in a masters’ program in mathematics education. In the teaching sequences, setting the scene for the students’ modelling of authentic problems by DE, it was indispensable to include a variety of digital resources such as databanks and software for numerical solutions, graphical representations, and some sorts of simulations. Apps with simulations of commonly used DE models are widespread on the internet, some of them are user-friendly and elaborated to a degree that justify use of the term ready-made tools. The issue addressed in this article is whether such ready-made tools constitute shortcuts to the students’ modelling process and thereby obstacles in their learning of mathematics. For the analysis, the term direction of modelling was used to make a distinction between expressive and explorative modelling, respectively. Direction of modelling proved useful for the analysis of students’ learning not only with relation to the ready-made tool but also more generally. In line with the author’s previous research, students’ learning of mathematics by modelling was conceptualised in terms of emergent models and modelling and detected by textual analysis of students’ written reports. The study gave new insight into the students’ learning processes in the form of a variety of patterns for interplay between the tool use and the learning of mathematics. This variety seems to be pivotal for the designs of modelling sequences in general and particularly in the case of DE due to their dependence on digital resources.
Safe and sound: examining the effect of a training targeting psychological safety and trust in peer assessment
Authors: Senden Morgane , De Jaeger Dominique , Coertjens Liesje
Published: June 2023

Introduction

Peer feedback can be very beneficial for student learning in higher education, yet students may feel uncomfortable providing and receiving peer feedback: they may for example not feel safe in the group or have little trust in their peers’ abilities to provide feedback. Surprisingly, only few studies have investigated how students’ feelings of discomfort can be reduced. To fill this gap, we created a 1-h training session using active learning methods. The training focuses on enhancing students’ perceptions of psychological safety, trust in their abilities and in their peers’ abilities to provide feedback.

Methods

The efficacy of this training was tested using a quasi-experiment with pre-and post-test design. Third-year bachelor students in physical education participated in a peer feedback activity to fulfill the requirement of an obligatory course. In 2019–2020, 47 students participated in a peer assessment activity without specific training on psychological safety and trust (control group), while in 2021–2022, 42 students received specific training before peer assessment (experimental group).

Results

Analyses include a comparison of the control and experimental groups with regard to (1) the evolution of their perceptions (psychological safety, trust in their abilities, and trust in their peers’ abilities) for pre-to post-test, (2) the quality of the feedback they provided to their peers (3) and the improvement of students’ work between the draft submitted for the peer activity and the final version submitted to the professor.

Discussion

Results do not support the training’s efficacy, yet suggest pathways for future research.