bluuebunny/crossref_metadata_2025 huggingface dataset:
Survival of persons living with HIV/AIDS: A multicentric study from India
Authors: Sinha Sanjeev , Samad Sameer Abdul , Bansal Garima , Verma Saurav , Sangle Shashikala A. , Guha Subhasish Kamal , Rajput Neetu , Thukral Himanshu , Pandey R. M. , Desai Devashish , Ranjan Sanjay , Salvi Sonali , Mundhe Sanjay , More Monika , Modak Dolanchampa , Datta Kalpana , Kabra S. K. , Lodha Rakesh , Das Bimal K
Published: March 2022

Persons living with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) (PLHA) enrolled from antiretroviral therapy (ART) centers located in three different cities in India – Delhi, Pune and Kolkata, and were followed up at six monthly intervals monitoring the WHO stage, CD4 counts, complete blood counts and liver and kidney function tests, for a duration of three years. The incidence of mortality among HIV/AIDS patients on ART was 5·0 per 1000 patient years (21/1410, 1.4%). Age at initiation of ART being above 35 years was the only significant predictor of mortality (log rank p = 0·018). Multivariable analysis showed significant association of an unfavourable outcome (defined as mortality or development of opportunistic infection during follow-up) with male gender (adjusted odds ratio (AOR) = 5.26, p = < 0.01) and being unmarried at ART initiation (AOR = 1.39, p = 0.005). The survival of PLHA with good adherence to ART is independent of the WHO stage or CD4 counts at initiation of ART.
Cholesterol Pleural Effusion caused by Tuberculosis: Case Report and Systematic Review of the Literature
Authors: Wang Le , Zhou Daming , Hu Haitao , Yu Wenqing , Ding Mingdong , Zhang Wei , Zhang Yun , Li Yang , Du Zhixiang
Published: March 2022

Background:
Pleural effusion (PE) is a common disease in clinical practice. Cholesterol PE or pseudochylothorax is a special type of exudative PE. For the lack of deep understanding of cholesterol PE, it is easy to misdiagnose in clinical practice.
Case presentation:
A 65-year-old male patient was diagnosed with Secondary tuberculosis (both lungs, smear positive, initial treatment), Tuberculous pleurisy, Cholesterol Pleural Effusion. 800 ml yellow pleural effusion (“Motor-oil” appearance) was drained from the patient’s pleural space after admission. A large number of crystals were observed from the patients’ pleural effusion. The level of Cholesterol (CHOL) of the patients’ PE was 11.41mmol/L. According to the weight of the patients, Isoniazid (0.3g/d), Rifampicin (0.45g/d), Pyrazinamide (2g/d), and Ethambutol (0.75g/d) were used to treat tuberculosis. And small doses of glucocorticoids (start with 32 mg of methylprednisolone, then decrease by 8 mg every week, and stop after 4 weeks) were used to inhibit pleural effusion. The pleural effusion was obviously absorbed, and the sputum smear was negative of the patient subsequent to his visit On May 22, 2021
Conclusions:
Cholesterol PE is a rare condition that mainly results from tuberculosis or rheumatoid diseases. “Motor-oil” appearance, numerous rhomboid-shaped cholesterol crystals, and pleural fluid cholesterol (PFCHOL) higher than 200 mg/dL are the key characteristics of Cholesterol PE. The treatment of Cholesterol PE is dependent upon the underlying disease. Glucocorticoid seemed to be an effective adjunctive therapy for Cholesterol PE.
Human vitelline vein remnant originating from the umbilical cord, passing though the extracelomic cavity of physiological herniation and ending at the midgut mesentery
Authors: Kim Ji Hyun , Jin Zhe-Wu , Yamamoto Masahito , Murakami Gen , Abe Shin-ichi , Rodríguez-Vázquez José Francisco
Published: March 2022

Purpose: The mechanism and timing of the degeneration and disappearance of the upstream portion of the human vitelline vein (VV) are unclear. Methods: Sagittal and horizontal histological sections from eight embryos and 19 fetuses (gestational age approximately 6-12 weeks; crown-rump length 11-61 mm) were examined. Results: Two types of VV candidates were observed: a long VV on the right superior side of the mesentery of the jejunum (VV1) and a short VV on the left inferior side of the mesentery (VV2). The VV1, observed in 12 specimens, was 20-30 microns in diameter and ran dorsally between the right liver lobe and the jejunum, subsequently merging with an initial superior mesenteric vein on the pancreatic head immediately below the superior portion of the duodenum. The VV2, observed in four specimens, passed dorsally between loops of the ileum on the left side of the mesentery of the ileum and ended at the mesentery. Many of these candidates did not originate from the umbilical cord but suddenly started in the sack of physiological herniation. Conclusions: At 10-12 weeks, the VV candidates originated from the umbilicus and were involved by the expanding greater omentum. The right-sided and left-sided VVs seemed to correspond to right and left VV remnants, respectively, and both took an upstream course outside the mesentery of the jejunum and ileum. The right VV upstream portion was likely to disappear later than the left one, but the timing of degeneration varied greatly among individuals, depending on the topographical relationship between the right liver lobe and the jejunum.
A case of double primary carcinoma was accidentally found during operation: hepatocellular carcinoma and appendiceal mucinous adenocarcinomas
Authors: Li Hai-Liang , Zhou Yi , Gao Peng , Zeng Xian-Cheng , Zhang Guo-Wei , He Bo-Hao
Published: March 2022

Background: Synchronous double primary cancer consisting of hepatocellular carcinoma (HCC) and appendiceal mucinous adenocarcinomas has not been reported in the world so far. Liver metastasis of digestive tract tumor is so common that it is easy to ignore the existence of double primary cancer in the digestive system. Appendiceal malignant tumor itself is easy to be misdiagnosed or missed. For the better understanding of HCC and appendiceal mucinous adenocarcinomas, the information of our recent case has been summarized.Case presentation: A 58-year-old man was admitted with repeated upper abdominal pain for one week. Imaging examination and liver biopsy pathology were diagnosed as hepatocellular carcinoma. Colonoscopy showed no obvious organic lesions in the terminal ileum and the whole large intestine. We had anatomical resection of S5, S6 segment of liver. At the same time, two suspicious lesions in the right liver were ablated by microwave. But at the end of the operation, we accidentally found a hard mass about 3cm x 3cm in size at the end of the appendix. And the rapid pathological results showed appendiceal adenocarcinoma, so we had a right hemicolectomy. So far, the diagnosis of the patient was changed to synchronous double primary cancer consisting of HCC and appendiceal mucinous adenocarcinomas.Conclusions: It is the first time we report a case of synchronous double primary hepatic cancer consisting of HCC and appendiceal mucinous adenocarcinomas in the world. Due to the rarity and unspecific clinical features, it is extremely challenging to be diagnosed preoperatively. It requires us to have a more comprehensive understanding of the patient's medical history, careful physical examination and comprehensive exploration of the abdominal cavity during the operation, so as to avoid missed diagnosis. Patients with HCC and appendiceal mucinous adenocarcinomas are generally associated with poor prognosis. It needs we put forward new countermeasures for the new question.
Using Next-generation Sequencing as Auxiliary Tool to gastric cancer with multiple intrahepatic neoplasms Diagnosis:primary cholangiocarcinomas or liver metastasis
Authors: xu fangye , xiao chunmei , shen kai , wang rong , he yuange , Xu Jiali , Liu Lianke
Published: March 2022

Since the pathogenesis of gastric cancer (GC) is generally disguised, with no unique clinical symptoms and manifestations, most patients have evolved to the advanced stage at the time of diagnosis when liver metastases are more likely to develop. Clinical diagnosis of liver metastasis in GC mainly depends on physical imaging methods, such as B-scan ultrasonography, computed tomography (CT), magnetic resonance imaging (MRI), etc. Histopathologic diagnosis is the gold standard for differentiating both primary cancer and metastasis. Next-Generation Sequencing (NGS), a relatively new technique, is increasingly being employed in clinical settings to guide diagnosis and treatment. Here, we report a patient with gastric cardiac adenocarcinoma who developed multiple intrahepatic neoplasms more than one year after total gastrectomy. Enhanced chest CT showed there may be metastatic lesions, but primary liver carcinomas should be excluded, while percutaneous core needle biopsy of the liver suggested that it was invasive or metastatic carcinoma and immunohistochemistry (IHC) was recommended for further diagnosis. Then further IHC examination suggested that it was consistent with cholangiocarcinoma. We treated the patient as having double primary carcinoma of GC and cholangiocarcinoma. However, based on the consistency of genetic testing in gastric and liver tissues for somatic mutations and certain copy number variants (CNVs), as well as the imaging examination, with the assistance of multidisciplinary team (MDT), finally we concluded that the patient should be diagnosed with a GC with liver metastasis, which suggested that NGS, a promising and auxiliary diagnostic tool, can be beneficial when the histopathology is ambiguous.
Adherence to Pre-Operative Fasting Guidelines and Associated Factors Among Pediatric Surgical Patients in Selected Public Referral Hospitals, Addis Ababa, Ethiopia: Cross Sectional multicenter Study
Authors: Yimer Aragaw Hamza , Haddis Lidya , Abrar Meron , Seid Ahmed Muhye
Published: March 2022

Background
Fasting of children before anesthesia is mandatory with the aim of to reduce the complications of due to regurgitation, vomiting, aspiration during anesthesia and surgery. Prolonged fasting times have several negative implications in children due to high fluid turnover quickly leads to dehydration, hypotension, metabolic disturbances and hypoglycemia which lead to poor anesthetic outcomes.
Aims
The aim of this study was to assess adherence to preoperative fasting guidelines and associated factors among pediatrics patients undergoing elective surgery in Addis Ababa selected Public Hospitals, Ethiopia, 2020.
Methods
A cross-sectional survey was conducted in Addis Ababa selected Public hospitals, Ethiopia, 2020. A total sample of 279 pediatric patients with age up to 17 years scheduled for elective surgery included in the data collection. The data analysis was done with SPSS V.21 and the value of the variables and its associated factors was checked its association with logistic regression. Significance was determined at P -value < 0.05. The result was presented by using text, tables, charts, and graphs.
Results
A total of 279 pediatric patients were responded in the analysis, with a 98.6% response rate. Majority of the participants 251(89.96%) were not followed the guidelines of preoperative fasting. The mean fasting time for clear liquids was 10 ± 4.03 (2–18 hrs.), for breast milk 7.18 ± 2.26 (3.5–12 hrs.), and for solid foods 13.5 ± 2.76 (8–19 hrs.). The reasons for which the preoperative fasting delayed was due to incorrect order 35.1%, prior cases procedures took longer times 34.1%, and changing sequence of schedule was 20.8%.
Conclusion
The majority of children were still having prolonged fasting practice. The staff’s instructions and sequences of schedules are challenged to follow the international fasting guidelines protocol.
Mining of the biosynthetic potential of archaea reveals diverse anti-archaeal lanthipeptides
Authors: Liang Haoyu , Song Zhiman , Zhong Zheng , Zhang Dengwei , Yang Wei , Zhou Le , Older Ethan , Li Jie , Wang Huan , Zeng Zhirui , LI Yongxin
Published: March 2022

Microbes produce diverse secondary metabolites (SMs) such as signaling molecules and antimicrobials that meditate microbe-microbe interaction. Archaea, the third domain of life, are a large and diverse group of microbes that not only exist in extreme environments but are abundantly distributed throughout nature. However, our understanding of archaeal secondary metabolites lags far behind our knowledge of those in bacteria and eukarya. In particular, the metabolic origin of antagonistic interactions which shape the archaeal community remains elusive. Here, we analyze 7,157 de-replicated archaeal genomes to investigate the biosynthetic potential of archaeal SMs systematically, revealing 5,496 biosynthetic gene clusters (BGCs). Up to 2,079 BGCs encoding highly diverse ribosomally synthesized and post-translationally modified peptides (RiPPs) are widely distributed across the Archaea domain. Guided by genome mining, we discover three new lanthipeptides with diverse ring topologies from a halophilic archaeon of class Haloarchaea. Of these there lanthipeptides, a representative exhibited anti-archaeal activities against closely-related halophilic archaea, potentially mediating the archaeal antagonistic interactions. These discoveries of the widespread archaeal ribosomal peptide SMs are expected to stimulate the experimental study of poorly characterized archaeal chemical biology and highlight the potential of archaea as a new source of bioactive SMs.
Case-Case and Case-Control Genome-Wide Association Study, Polygenic Risk Score and Classical HLA Alleles Analysis of Cervical Human Papillomavirus (HPV)
Authors: Adebamowo Sally N. , Adeyemo Adebowale , Adebayo Amos , Achara Peter , Alabi Bunmi , Bakare Rasheed A. , Famooto Ayotunde O. , Obende Kayode , Offiong Richard , Olaniyan Olayinka , Ologun Sanni , Rotimi Charles ,   ACCME Research Group as part of the H3Africa Consortium, Adebamowo Clement A.
Published: March 2022

Genetic variants that underlie susceptibility to high-risk cervical human papilloma virus (hrHPV) infections are largely unknown. We conducted discovery case-case and case-control genome-wide association studies, replication, and meta-analysis, generated polygenic risk scores and examined the association of classical HLA alleles and cervical human papillomavirus (HPV) infections in a cohort of over 10,000 women. We identified genome-wide significant variants for prevalent hrHPV around LDB2 and for persistent hrHPV near TPTE2, SMAD2, and CDH12, which code for proteins that are significantly expressed in the human endocervix. Genetic variants associated with persistent hrHPV are in genes enriched for the antigen processing and presentation gene-set. HLA-DRB1*13:02, HLA-DQB1*05:02 and HLA-DRB1*03:01 were associated with increased risk and HLA-DRB1*15:03 with decreased risk of persistent hrHPV. The findings of this study expand our understanding of genetic risk factors for HPV persistence and highlight the role played by MHC class II molecules in clearing hrHPV after initial infection.
Urine specimen collection for diagnosing a urinary tract infection-patient experience and preference for urine specimen collection: A Qualitative Study
Authors: Collins Linda , Khasriya Rajvinder , Malone-Lee James
Published: March 2022

BackgroundA urinary tract infection (UTI) is very common and patients frequently present to their General Practitioner and emergency department with symptoms. Diagnosis of the infection is made by examining fresh urine with microscopy, to detect white cells and epithelial cells shed from the bladder or by submitting the urine for microbial culture. Patients are often requested to provide a urine specimen, but very little is known about the patient experiences of carrying out the task or their preference of specimen collection method. The aim of this study was to explore patient experiences and preferences between four different urine specimen collection methods for diagnosing the presence of a UTI.MaterialsSemi-structured interviews were conducted to explore patient experiences of four different urine specimen collection methods (midstream urine specimen (MSU), catheter specimen (CSU), Peezy MSU™ and Natural void). The interviews consisted of four open-ended questions and all data were collated and organised using NVivo to establish themes that emerged from the data.ResultsThe natural void without technique was repeatedly referred to and was regarded as being the most straightforward of all of the sampling methods. Pain symptoms were described only in the catheter method and not in the MSU, Peezy MSU™ or natural void method. The catheter was regarded as the urine collection method that produced the best specimen for diagnostic testing by the patients’.ConclusionA majority of the participants expressed the desire for straightforward urine sampling methods and preferred the natural void as a standard method in clinical practice.
Rapid naked-eye tracking of on-cell phenotype based on dual-aptamers-weaved cascade assembly of nanostructures
Authors: Li Genxi
Published: March 2022

Phenotypic plasticity is an emerging paradigm for providing biological and clinical insights into cancer initiation, progression, and resistance to therapy. However, it is a great challenge to tracking phenotypic information on live cells with high levels of sensitivity, specificity, and simplicity, when specific cancer cell subset is being targeted. In this work, we have successfully achieved cascade assembly of nanoparticles on the surface of specific cancer cells by design of a dual-aptamers-weaved molecularly AND logic system. Taking advantages of spatial addressability, precise controllability, and targeting recognition of the nanostructure assemblies, we can precisely label the target cell subset in large population of similar cells and rapidly obtain phenotypic information in response to the surface changes of captured cancer cells. Without sophisticated instruments, we can know the phenotypic information on HepG2 cells in whole blood with high level of sensitivity, and rapid naked-eye tracking of on-cell phenotype changes of HepG2 cells undergoing epithelial-mesenchymal transition (EMT).
PENGARUH MOBILE BANKING, BOPO, DPK, DAN TRANSAKSI VALAS TERHADAP FEE BASED INCOME
Authors: Rahayu Sherlita Ribkha , Lestari Murti
Published: March 2022

ABSTRAKLayanan jasa perbankan merupakan kegiatan yang dilakukan bank untuk menunjang kegiatan utamanya. Layanan jasa perbankan menghasilkan pendapatan berupa fee atau dikenal dengan fee base income. Pesatnya perkembangan teknologi mendorong industri perbankan untuk berinovasi, terutama pada produk layanan jasa. Penelitian ini bertujuan untuk menganalisis bagaimana pengaruh Beban Operasional Pendapatan Operasional (BOPO), Dana Pihak Ketiga (DPK), transaksi valas, dan Mobile banking (M-banking) terhadap fee based income. Teknik pengambilan sampel yang digunakan adalah teknik purposive sampling. Sampel yang digunakan adalah Bank Swasta Nasional dengan nilai asset terbesar di Indonesia periode 2006-2020. Analisis data yang digunakan dalam penelitian ini adalah regresi data panel (pooled). Penelitian ini menggunakan Model Regresi Fixed effect. Hasil Penelitian menunjukan bahwa transaksi valas berpengaruh positif signifikan terhadap fee based income. Sedangkan BOPO, DPK, dan M-banking tidak berpengaruh signifikan terhadap fee based income.Kata Kunci: BOPO, DPK, transaksi valas, M-banking, fee base income, Regresi Fixed effectABSTRACTBanking services are activities carried out by banks to support their main activities. Banking services generate income in the form of fees or known as fee base income. The rapid development of technology encourages the banking industry to innovate, especially in service products. This study aims to analyze how the influence of Operating Income Operating Expenses (BOPO), Third Party Funds (DPK), foreign exchange transactions, and mobile banking (M-banking) on fee based income. The sampling technique used is purposive sampling technique. The sample used is the National Private Bank with the largest asset value in Indonesia for the period 2006-2020. The data analysis used in this study is panel data regression (pooled). This study uses the Fixed effect Regression Model. The results of the study show that foreign exchange transactions have a significant positive effect on fee-based income. Meanwhile, BOPO, DPK, and M-banking have no significant effect on fee-based income.Keywords: BOPO, DPK, foreign exchange transactions, M-banking, fee base income, Regression Fixed effect
Stages of crisis counseling interventions on abortus provocatus performers in pregnancy due to rape
Authors: Nahdhiyyah Husnun
Published: March 2022

Purpose -  The purpose of this study was to discuss the stages of counseling intervention for provocative abortion perpetrators in pregnancy due to rape.  Method - The research method used in this article is library research. The research was conducted by collecting information and data with the help of various materials in the library such as books, previous research results, articles, notes and various journals related to the problem to be solved systematically to collect, process, and conclude data using the method.Result - A perpetrator of abortus provocatus in pregnancy due to rape is in dire need of crisis counseling in terms of physical, psychological, and mental trauma. The stages of crisis counseling intervention carried out by the counselor are: defining the problem, ensuring the counselee's safety, providing support, examining alternatives, making plans, and getting commitments.Implications – This research has an impact on knowing the stages of crisis counseling intervention carried out by counselors.Originality – This research used literature deeply about the stages of counseling intervention for abortus provocatus perpetrators in pregnancy due to rape.***Tujuan - Tujuan penelitian ini untuk membahas tahapan intervensi konseling bagi pelaku aborsi provokatif pada kehamilan akibat perkosaan.Metode - Metode penelitian yang digunakan dalam artikel ini adalah penelitian kepustakaan. Penelitian ini dilakukan dengan mengumpulkan informasi dan data dengan bantuan berbagai bahan yang ada di perpustakaan seperti buku, hasil penelitian sebelumnya, artikel, catatan dan berbagai jurnal yang berkaitan dengan masalah yang akan dipecahkan secara sistematis untuk mengumpulkan, mengolah, dan menyimpulkan data menggunakan metode.Hasil - Pelaku abortus provokatus dalam kehamilan karena perkosaan sangat membutuhkan konseling krisis dari segi trauma fisik, psikis, dan mental. Tahapan intervensi konseling krisis yang dilakukan oleh konselor adalah: mendefinisikan masalah, memastikan keselamatan konseli, memberikan dukungan, memeriksa alternatif, membuat rencana, dan mendapatkan komitmen.Implikasi - Penelitian ini berdampak pada mengetahui tahapan intervensi konseling krisis yang dilakukan oleh konselor.Originalitas - Penelitian ini menggunakan literatur secara mendalam tentang tahapan intervensi konseling bagi pelaku aborsi provokatif pada kehamilan akibat perkosaan.
Counseling guidance in improving family stability in facing a covid-19 pandemic
Authors: Umam Rois Nafi'ul
Published: March 2022

Purpose – The purpose of this study is to provide a clear description of the issue of family stability during the pandemic and family counseling guidance as to the solution in improving family stability.Method – This study applied a descriptive qualitative approach with an interview as the technique to collect the data. The informants in this study were 5 people consisting of the executive board and the members of Al-Usroh family community in Balikpapan.Result - The result of the study shows that during the pandemic the issues influencing family stability are family financial crisis, boredom, and over anxiety. To improve family stability during the pandemic, family counseling guidance with a conjoint approach was carried out.Implication – This research might become a study on the application of family counseling guidance services to improve family stability.Originality – This study was about the effect of the covid-19 pandemic towards family stability and the role of family counseling guidance to improve family stability.***Purpose – Tujuan penelitian ini adalah untuk memberikan gambaran tentang masalah ketahanan keluarga di masa pandemi dan layanan bimbingan konseling keluarga sebagai solusi dalam meningkatkan ketahanan keluargaMethod – Penelitian ini menggunakan pendekatan kualitatif deskriptif dengan teknik pengumpulan data wawancara. Informan dalam penelitian ini sebanyak 5 orang yakni dari pengurus dan anggota komunitas keluarga Al-Usroh BalikpapanResult  -  Hasil penelitian menunjukkan bahwa permasalahan di masa pandemi yang berpengaruh terhadap ketahanan keluarga seperti krisis finansial pada keluarga, kejenuhan dan kecemasan yang berlebihan. Dalam rangka meningkatkan ketahanan keluarga di masa pandemi ini, upaya yang dilakukan yakni melalui layanan bimbingan konseling kelompok dengan pendekatan conjoint.Implication – Penelitian ini dapat menjadi kajian tentang pemanfaatan layanan bimbingan konseling keluarga untuk meningkatkan ketahanan keluargaOriginality – Penelitian ini adalah penelitian tentang dampak pandemi covid-19 terhadap ketahanan keluarga dan peran bimbingan konseling keluarga untuk meningkatkan ketahanan keluarga
PEMBERDAYAAN EKONOMI MASYARAKAT BERBASIS MASJID Studi Kasus di Masjid Baiturrahman Klidon Sinduharjo Ngaglik Sleman
Authors: Muslim Azis
Published: March 2022

In Indonesia todays, the number of mosques, according to the Indonesian Council of Mosques, is no less than 700 thousand mosques. This number represents the greatest number of mosques in the world. From the large number of those, only a small portion has still been developed for handling poverty problems. Based on ths issue, it is necessary examine the Baiturrahman Mosque in Klidon Sinduharjo Ngaglik Sleman. This study will investigate and describe the success of economic empowerment achieved by the mosque, especially in tackling the poverty problems among the surrounding congregation of societies. The study shows that the managements of Baiturrahman mosque operate some stages  in empowering the local economy. First, they build management phases, such as building the perception of stakeholders regarding the mosque function, managing the mosque in accordance with modern management, and building success dreams. Second, they apply the management principles, such as serving the congregations, making innovation and creativity for them, giving and enhancing the congregations rule in the mosque. Third, they choose the right strategy, such as starting to do the simplest and easiest thing, as well as considering the ongrgations’ interests. ****Di Indonesia, jumlah masjid menurut Dewan Masjid Indonesia tidak kurang dari 700 ribu masjid. Jumlah ini merupakan jumlah terbesar dari masjid di dunia. Dari jumlah tersebut, hanya sebagian kecil masih dikembangkan untuk menangani masalah kemiskinan. Berdasarkan masalah tersebut, perlu melihat Masjid Baiturrahman di Klidon Sinduharjo Ngaglik Sleman. Peneliti-an ini akan menyelidiki dan menggambarkan keberhasilan pemberdayaan ekonomi yang dicapai oleh masjid, terutama dalam menanggulangi masalah kemiskinan di antara jama’ah sekitar masyarakat. Studi ini menunjukkan bahwa manajemen masjid Baiturrahman mengoperasikan beberapa tahapan dalam memberdayakan ekonomi lokal. Pertama, membangun manajemen, seperti membangun persepsi stakeholders mengenai fungsi masjid, mengelola masjid sesuai dengan manajemen modern, dan mimpi membangun kesuksesan. Kedua, menerapkan prinsip-prinsip manajemen, seperti melayani jama’ah, membuat inovasi dan kreativitas bagi mereka, memberikan dan meningkatkan jama’ah di masjid. Ketiga, memilih strategi yang tepat, seperti mulai melakukan hal yang sederhana dan mudah, serta mempertimbangkan kepentingan organisasi.
PENGARUH KETAATAN BERIBADAH TERHADAP KESEHATAN MENTAL MAHASISWA UIN WALISONGO SEMARANG
Authors: Mahfud Dawam , Mahmudah Mahmudah , Wihartati Wening
Published: March 2022

The purpose of this research is to measure the level of influence of obedience worship to scholar mental hygiene in Walisongo State Islamic University Semarang. The population in this research is all of scholar in Walisongo State Islamic University Semarang. The method to collecting data use questionare and mental hygiene scale and obedience worship scale. To analyze use infential parametris statistic with simple regression and t-test. This research shows that there are influence of obedience worship to mental hygiene scholar in Walisongo State Islamic University. The average of scholar mental hygene value  is 78,2000 with deviation standart 6,14175, and average of obedience worship value is 94,3636 with deviation standart 6,58985 with influence coefficient F is 47,096 with significance value (pvalue) 0,000.***Penelitian ini bertujuan  mengukur besarnya pengaruh ketaatan beribadah terhadap kesehatan mental mahasiswa IAIN Walisongo Semarang. Populasi dalam penelitian ini adalah seluruh mahasiswa IAIN Walisongo Semarang. Teknik pengambilan sampel dilakukan dengan teknik Stratified Sampling. Teknik pengumpulan data menggunakan angket dan skala kesehatan mental dan skala ketaatan beribadah. Teknik analisis data menggunakan teknik statistik inferensial parametris dengan teknik analisis regresi sederhana dan uji t. Hasil temuan dalam penelitian ini adalah: Ada pengaruh ketaatan beribadah terhadap kesehatan mental mahasiswa UIN Walisongo Semarang, semakin tinggi pengaruh ketaatan beribadah maka semakin tinggi kesehatan mental mahasiswa UIN Walisongo Semarang. Sebaliknya, semakin rendah pengaruh ketaatan beribadah maka semakin rendah pula kesehatan mental mahasiswa IAIN Walisongo Semarang. Rata-rata nilai kesehatan mental mahasiswa 78, 2000 dengan standar deviasi 6,14175, sedangkan rata-rata nilai ketaatan beribadahnya 94,3636 dengan standar deviasi 6,58985 dengan koefisien pengaruh F sebesar 47,096 dengan nilai signifikansi (Pvalue) 0,000.
Rekonstruksi dakwah era revolusi media studi kasus pergolakan Front Pembela Islam
Authors: Zaman Muchammad Machrus , Nurchois Ahmad
Published: March 2022

This research that is Islam in Indonesia is a religion in great demand by the public (the majority). This at the same time brings Islamic da'wa to various kinds of developments. The dynamics of the development of da'wa from time to time also experienced significant changes from various aspects. In addition, many Community Organizations (Ormas) were established to strengthen resilience. Where should be with the frills of the majority of Muslims, able to preach very freely and easily accepted by the community? However, in reality, people are increasingly afraid because many community organizations (Ormas) have different opinions and blame each other. The Islamic Defenders Front (FPI) is one of the Islamic community organizations (Ormas) that emerged because of its controversial preaching. This study uses a qualitative method with a historical approach, while the research specifications used are descriptive. The results of the study show that da'wa in the current era is experiencing a setback due to the pros and cons of Islamic community organizations (Ormas). Because the majority of Muslims in Indonesia are only concerned with the social status of each individual, not mutually reinforcing one another. Therefore, this incident can be overcome with Islamic community organizations (Ormas) who preach according to Islamic law, not by violence, both verbally and physically, and mutually reinforcing towards an Indonesian Islam that is Rahmatan Lil Alamin.***Penelitian ini dilatarbelakangi bahwa agama Islam di Indonesia menjadi agama yang banyak diminati oleh masyarakat (Mayoritas). Hal ini sekaligus membawa dakwah Islam menuai berbagai macam perkembangan. Dinamika perkembangan dakwah dari masa ke masa pun mengalami perubahan yang signifikan dari berbagai aspek. Selain itu, banyak Organisasi Masyarakat (Ormas) yang didirikan guna memperkuat ketahanan. Di mana seharusnya dengan embel-embel mayoritas umat Muslim, mampu berdakwah dengan sangat leluasa dan mudah diterima oleh masyarakat. Namun kenyataannya, masyarakat semakin takut karena banyaknya Organisasi masyarakat (Ormas) yang berbeda pendapat dan saling menyalahkan satu sama lain. Front Pembela Islam (FPI) menjadi salah satu Organisasi masyarakat (Ormas) Islam yang muncul karena dakwahnya yang kontroversial. Penelitian ini menggunakan metode kualitatif  dengan pendekatan historis, sedangkan spesifikasi penelitian yang digunakan adalah deskriptif. Hasil penelitian menunjukkan bahwa dakwah di era saat ini mengalami kemunduran yang diakibatkan pro-kontra Organisasi masyarakat (Ormas) Islam itu sendiri. Karena mayoritas Muslim di Indonesia hanya mementingkan status sosial setiap individu, bukan saling menguatkan satu sama lain. Oleh karenanya kejadian ini bisa diatasi dengan Organisasi masyarakat (Ormas) Islam yang berdakwah sesuai syari’at Islam, tidak dengan kekerasan baik secara verbal maupun fisik dan saling menguatkan untuk menuju Islam Indonesia yang Rahmatan Lil Alamin.
A robust real-time flood forecasting method based on error estimation for reservoirs
Authors: Shen Dandan , Bao Weimin , Ni Peng
Published: March 2022

The observed discharge, an important input for flood forecasting systems, can significantly affect the accuracy of forecasting results. Since the reservoir inflow is not measured directly but calculated based on the observed reservoir stage and the reservoir outflow, it always contains gross errors causing some inflow to be outliers. In this study, a robust error estimation method for real-time flood forecasting has been developed for reservoirs’ data processing. The method differs from the conventional flood forecasting method, in that it represses the gross errors by a robust loss function based on the real error distribution of measurements. Furthermore, a fluctuation coefficient has been proposed to quantify the degree of fluctuation of a jagged reservoir inflow. The performance of the method is evaluated by both synthetic data and real cases. By using floods generated synthetically by an ideal model in which the true values and errors are known, the method is shown to be efficient as theoretically expected. The results show that the method is efficient and universally applicable in different cases. And the degree of forecast improvement is positively related to the fluctuation coefficient of the floods. The more severe the fluctuation of the flood hydrograph, the more robust the method.
Spatiotemporal water quality variations in the urbanizing Chongqing reach of Jialing River, China
Authors: Long Xunjian , Zhang Yi , Ye Yan , Ye Yong , Xu Tingbing , Li Tianyang
Published: March 2022

Water quality in rivers usually exhibits markedly spatiotemporal variations as affected by urbanization, while the magnitude of these effects remain unclear. This study aimed to investigate the spatiotemporal water quality variations in the urbanizing Chongqing reach of Jialing River and its tributary using a 6-yr multisite dataset (January 2010–December 2015). Water quality variables including pH, dissolved oxygen (DO), permanganate index (CODMn), ammonia nitrogen (NH3-N) and total phosphorus (TP) were deciphered. Results showed that the trunk river displayed respectively 1.2 and 39.8% higher pH and DO concentration but 66.9, 94.7 and 85.2% lower CODMn, NH3-N and TP concentrations relative to the tributary (P < 0.05), due largely to the dilution effects occurring in the trunk river. The dry season presented respectively 1.3, 18.2, 102.8 and 32.5% higher pH, DO, NH3-N and TP concentrations than those in the wet season (P < 0.05). DO concentration showed significant inter-annual variations (P < 0.05), and CODMn, NH3-N and TP concentrations all presented markedly declining trends from 2010 to 2015 (P < 0.05). Significant relationships among the study variables were found in different spatiotemporal scales (P < 0.05). Our results are valuable to optimize strategies for sustainable water quality management in rivers experiencing urbanization worldwide.
Alterations in Clinical Characteristics of Blood Donors Post COVID-19 Recovery
Authors: Ghamdi Fahad Al , Naqvi Salma , Alabassi Fahad A. , Alhayyani Sultan , Baig Mirza Rafi , Kumar Vikas , Anwar Firoz
Published: March 2022

Background:

Corona Virus Disease-19 (COVID-19), a current worldwide pandemic is the cause of
serious concern. Risk-adjusted differences in outcomes of the patients are not well characterized. Therefore,
susceptibility to infection with respect to blood group, blood pressure, pulse rate, hemoglobin, age, and BMI is
analyzed in this study.

Methods:

Blood donors of all ages and gender, who recovered from COVID-19 infection, were selected for the
study. Samples were collected from the regional laboratory and the central blood bank of Hafr al Batin, Saudi
Arabia. Out of 1508 healthy blood donors, 134 had recovered from corona without any preexisting diseases.

Results:

Major donors were male (85.1%). 28% of donors were in the age range of 26-35 years. O+(32.8%) donors
were in majority. Systolic and diastolic blood pressure and pulse rate elevated significantly in the age
group 46-55 (p<0.05) and 56-65 (p<0.001). Systolic blood pressure in males (134.13 ± 9.57) was significantly
higher (p<0.05) than in females (129.35 ± 10.61). Donors with Rh+ had significantly higher systolic (p<0.05)
and pulse rate (p<0.05) as compared to Rh–.

Discussion:

O+ donors were found to be highly susceptible. Blood pressure, pulse rate and Hb altered with age.
Males exhibited higher variation in systolic blood pressure, with the Rh+ factor playing a predominant role. Donors
above 45-years of age and with a high BMI had significantly elevated blood pressure and pulse. These results
are challenging or contradictory to the results of Turkish and Chinese studies where blood group A+ was
more predominantly affected by the SARS-CoV-2 with the minimum infection rate in females and Rh- donors.

Conclusion:

Factors like blood group, age, physical characteristics and BMI should be taken into account before
initiating any therapeutic approach to obtain the best possible outcomes with minimum adverse effects
from the current drugs utilized for SARS CoV-2 treatment, especially with the age group of 45 years and above.
Inadequate PTH Response to Hypocalcemia in People Living with HIV
Authors: Noe Sebastian , Jonsson-Oldenbuettel Celia , Jaeger Hans , Schoenitzer Veronika , Balogh Annamaria , Wolf Eva , Arc HIV study group
Published: March 2022

Background:

Small experimental studies suggest that PTH-secretion following hypocalcemia
might be blunted in people living with HIV.

Objective:

The aim of the study was to estimate the frequency of inadequately low concentrations of
parathyroid hormone in the presence of hypocalcemia in people living with HIV.

Methods:

This was a retrospective study that was conducted among PLWH enrolled in the ongoing
ArcHIV study between 2016 and 2017. PLWH with routine measurements for both calcium and parathyroid
hormone levels were included in this analysis. The proportion of patients with a combination
of low levels of both calcium and parathyroid hormone was the primary endpoint of this analysis.

Result::

496 PLWH were included (mean age 47.1 (± 10.2) years, 393 (79.2 %) men). In 14 (2.8
%) PLWH, low calcium levels with low levels of PTH were observed in the assessment conducted
in both years. Undergoing a tenofovir disoproxil-containing treatment in both years was the only
explanatory variable significantly associated with inadequately low levels of PTH in the presence of
hypocalcemia in both years (OR 4.3 [CI95: 1.4; 16.0]).

Conclusion:

The combination of low levels of both calcium and PTH was found more frequent in
our study sample when compared to what is expected from the general population. Interestingly, undergoing
a tenofovir disoproxil-containing therapy was associated with this combination throughout
both the years.
A Review on End-effectors of Robotic Grinding
Authors: Tang Dedong , Li Fengxiao , Jiang Jingang , Song Shichang , Zeng Yang
Published: March 2022

Background:

As a kind of device applied to grinding, the robot grinding end-effector,
combining force control structure, adaptive structure, and other structures, has been widely used in
machine grinding. Grinding end-effectors can greatly help industrial robot technology used in operations
that require continuous contact, such as polishing, grinding, deburring, chamfering, and
assembly. Therefore, the structure design of the end-effector will become an inevitable trend in the
research on robot grinding in the future.

Objective:

The existing grinding end-effectors for robot grinding are summarized, and their classification,
characteristics, and development are introduced.

Method:

Various products and designs related to grinding end-effectors are summarized. The
structural features, differences, and applications of typical grinding end-effectors are introduced.

Results:

Three typical end-effectors are analyzed. The structural features and functions are summarized,
and the development trend has been prospected. The current situation and future research direction
of grinding end-effector products and patents are discussed.

Conclusion:

Grinding end-effectors are classified into the force-controlled grinding end-effector,
the adaptive grinding end-effector, and the special structure grinding end-effector. The grinding
end-effector plays an important role in promoting the development of the robot grinding industry,
improving the surface quality of parts and the finishing process. The grinding end-effector needs
further improvement in image processing, humanization, force control, and so on. More in-depth
research should be carried out in this direction.
Environmental Benefits of the Central China Rise Strategy; Empirical
Analysis Based on the PSM-DID Model
Authors: Li Yingchun , Chi Yuanying , Li Jialin , Peng Rui
Published: March 2022

Background:

The Central China Rise Strategy is one of China’s important regional development
strategies, and it has been officially implemented since 2006. Despite the obvious economic
development resulting from the strategy, its impact on the environment remains unclear.

Objective:

Previous studies have focused more on the economic benefits of the Central China Rise
Strategy while ignoring its environmental impact. This paper focuses on the environmental benefits
and aims to promote the coordinated development between the economy and the environment.

Methods:

Panel data of 30 Chinese provinces from 2000 to 2017 were selected to construct a propensity
score matching-difference-in-difference (PSM-DID) framework for systematic research that
includes benchmark modeling, as well as dynamic effect and mechanism analyses.

Results:

①The benchmark model and placebo test proved that the Central China Rise Strategy had
increased environmental pollution.② Dynamic effect analysis revealed that the impact of the Central
China Rise Strategy on environmental pollution has gradually increased in the short- and medium-
term, with 2012 exhibiting the greatest augmentation, significantly reducing from 2016 onwards.
③The mechanism of action considers three mechanisms. The level of economic development
is a path through which the Central China Rise Strategy leads to the aggravation of environmental
pollution while the city size is not. Foreign direct investment has improved environmental
pollution.

Conclusions:

The Central China Rise Strategy has aggravated environmental pollution, especially in
the short and medium-term. In view of the mechanism path, we put forward three targeted suggestions.
In the future, we will study some of the limitations of this paper: more mechanisms of action
will be considered, and the use of new technologies, such as neural networks, will be compared with
our results.
Nicorandil and Bone Marrow-derived Mesenchymal Stem Cells Therapeutic
Effect after Ureteral Obstruction in Adult Male Albino Rats
Authors: Fawzy Amal , Abdel-Aziz Heba M. , Ibrahem Nahla E. , Mekawy Noura H. , Mohamad Noura Mostafa , Samy Walaa
Published: March 2022

Background:

Chronic kidney disease is a global health problem for which renal fibrogenesis
is the final treatment target.

Objective:

In our work, we have highlighted two new strategies, nicorandil and Bone marrow-derived
mesenchymal stem cells (BM-MSCs), as effective in reversing renal fibrosis induced by partial unilateral
ureteral obstruction (PUUO).

Methods:

The current study included 96 male albino rats randomly divided into four groups, with 24 rats
per group; Group I, the control group; Group II, PUUO, where two-thirds of the left ureter was entrenched
in the psoas muscle; Group III, same surgical procedure as in Group II for 7 days, and then the rats
received 15 mg/kg/day nicorandil once daily for 21 days; and Group IV, same surgical procedure as in
Group II for 7 days, and then rats were given 3 × 106 of labeled MSCs injected intravenous, and left for
21 days. Blood and kidney tissues were collected for biochemical, histological, and molecular analyses.

Results:

Both the nicorandil and BM-MSCs treatment groups could ameliorate kidney damage evidenced
by inhibition of MDA elevation and total antioxidant capacity reduction caused by PUUO. Also, there
was a significant reduction observed in TNF, TGF, IL6, collagen I, and α-SMA in addition to improvement
in histological examination. However, a significant difference was found between the BM-MSCs
and nicorandil-treated groups.

Conclusion:

Our results suggest that BM-MSCs and nicorandil improved renal fibrosis progression
through their antiapoptotic, anti-inflammatory, and antifibrotic effects in male albino rats subjected to
PUUO, with BM-MSCs being more effective compared to nicorandil.
REVIEW OF CUSTOMER EXPERIENCE, PERCEIVED EFFECTIVENESS OF E-COMMERCE INSTITUTIONAL MECHANISMS, AND REPURCHASE INTENTION FROM THE PERSPECTIVE OF EXPECTATION-CONFIRMATION THEORY
Authors:   Student at doctoral program, Faculty of Economics and Business, Universitas Gadjah Mada, Indonesia Lecturer at Faculty of Economics and Business, Universitas Dian Nuswantoro, Indonesia, Pakarti Piji , Dharmmesta Basu Swastha ,   Faculty of Economics and Business, Universitas Gadjah Mada, Indonesia, Nugroho Sahid Susilo ,   Faculty of Economics and Business, Universitas Gadjah Mada, Indonesia, Sutikno Bayu ,   Faculty of Economics and Business, Universitas Gadjah Mada, Indonesia
Published: March 2022

This study aims to determine how the influence of customer experience dimensions includes functionality factors and psychological factors on e-satisfaction, trust in sellers, and repurchase intentions by involving the perceived effectiveness of e-commerce institutional mechanisms (PEEIM). The sampling technique used purposive sampling with two research objects in Yogyakarta and Semarang. The number of samples is 208 respondents. Data was collected using a questionnaire instrument distributed online and analyzed using Partial Least Squares Structural Equation Modeling (PLS-SEM). The results showed that the variables of usability, communication, trust in the seller, and context familiarity had a positive effect on e-satisfaction. Social presence, product presence, interactivity, and value for money do not affect e-satisfaction. PEEIM positively affects trust in the seller. e-satisfaction directly or indirectly affects repurchase intentions. Further research is directed to develop a research model with a more detailed object focus to get a more comprehensive understanding, for example, by comparing the types of experience products and search products.