bluuebunny/crossref_metadata_2025 huggingface dataset:
First records of Arcyria marginoundulata Nann.-Bremek. & Y. Yamam. (Myxomycetes) in Poland
Authors: Ronikier Anna , Perz Piotr , Chachuła Piotr
Published: December 2013

A new to Poland species of a myxomycete, Arcyria marginoundulata, was found at two distant localities in the southern part of the country. Polish specimens are typical and have all important features characteristic of the species: minute, grey, stipitate sporocarps, calyculus concentrically plicate at margin, spiny capillitium and small spores covered with few irregularly distributed larger warts. The species was found growing on alder female catkins. It seems that this substrate is specific for A. marginoundulata in Europe.
New and rare species of Volvocaceae (Chlorophyta) in the Polish phycoflora
Authors: Dembowska Ewa A.
Published: December 2013

Seven species of Volvocaceae were recorded in the lower Vistula River and its oxbow lakes, including Pleodorina californica for the first time in Poland. Three species – Eudorina cylindrica, E. illinoisensis and E. unicocca – were found in the Polish Vistula River in the 1960s and 1970s, as well as at present. They are rare species in the Polish aquatic ecosystems. Three species are common both in the oxbow lakes and in the Vistula River: Eudorina elegans, Pandorina morum and Volvox aureus. New and rare Volvocaceae species were described in terms of morphology and ecology; also photographic documentation (light microscope microphotographs) was completed.
Phenolic acids in extracts obtained from the flowering herbs of Cirsium vulgare (Savi) Ten. growing in Poland
Authors: Kozyra Małgorzata , Głowniak Kazimierz
Published: December 2013

In this work the phenolic acids in the methanol extract from the flowering herbs of Cirsium vulgare (Savi) Ten. growing in Poland were isolated and identified. The samples containing free phenolic acids and those released after acid and alkaline hydrolyses were investigated by 2D TLC on cellulose. After purification by SPE, samples were also analyzed by RP-HPLC. Six phenolic acids such as gallic, protokatechuic, gentisic, hydrobenzoic, vanillic and caffeic acids were detected in the fraction of free phenolic acids of the methanol extract, irrespectively of the method used.
Institutional logics and social mechanisms: a pragmatic multilevel perspective
Authors: Costa Mayla Cristina , Teixeira Maísa Gomide
Published: December 2013

DOI: 10.5902/198346598220Institutionalists have argued about some different toolkit for addressing the paths of historical change in the different areas of research, including the development of a set of social mechanisms that may help to account for the impact of macro-level changes on the micro or individual level. In recent years institutional research has been focusing on institutional logics as an analytical approach with a higher potential to solve this puzzle. Therefore the main goal of this paper is to open a research stream onto a focus on a methodological approach and analytical tool to study multi-level relationships. For instance, a topic that has been claimed as still in need of more consideration, the understanding of how organizations are influenced by competing logics, and the implications of those logics in terms of practices performed by actors and group identity formation, could be better explored.
Análise bibliométrica da produção científica da Revista de Adminstração da UFSM: em busca de novas perspectivas e desafios
Authors: Kneipp Jordana Marques , Barbieri da Rosa Luciana Aparecida , Bichueti Roberto Schoproni , Pozzer Ranice , Schuch Junior Vitor Francisco
Published: December 2013

DOI: 10.5902/198346598551The Revista de Administração da Universidade Federal de Santa Maria (ReA/UFSM), founded in 2008, is an online publication of the Departamento de Ciências Administrativas of Centro de Ciências Sociais e Humanas from UFSM. The ReA/UFSM is gaining its place in academiaas an important vehicle for dissemination of publications in the business area. In this sense, this study aimed at analyzing the scientific publications of ReA/UFSM, in the period from 2008 to 2011. Thus, we analyzed all papers published in the periodic, in the last four years, representing 113 studies. Among the main results, it was found that the papers analyzed are mostly empirical, exploratory in nature, with qualitative approach predominantly. The analyzed data allow present an overview of the publications of ReA/UFSM, in the period from 2008 to 2011, enabling to defined new perspectives and challenges for the periodic.
O diálogo com stakeholders na teoria e na prática: análise da relação de uma empresa pública do setor industrial com seus stakeholders, para a construção de uma política de responsabilidade social
Authors: Teixeira Maria Gracinda Carvalho , Moraes Ivy Bertão de
Published: December 2013

DOI: 10.5902/198346598636 The aim of this article is to study the relationship between a public company of the industrial sector and its stakeholders showing the place they occupy in the construction of the company social responsibility policy (CSR). The meaning of the term stakeholder in theory and in the organization’s practice is a challenge in the delineation of interest groups formed along the historical trajectory of the organization. The premises of the corporate social responsibility policy, assume the company's attendance at economic and legal requirements related to their productive activities, in addition to the social and environmental impacts, in order to prevent, mitigate or compensate for the damages resulting from their activities. To adapt to this new reality organizations should incorporate new corporate values that promote the restructuring of their productive activities and the dialogue with stakeholders. The research results suggest that the environmental issues involving the company have spurred the intention to create of CSR and that the notion of stakeholder incorporated by the organization guides in delimitation of the participants in the company’s dialogue with their stakeholders to build a social responsibility policy.
Consumo consciente como determinante da sustentabilidade empresarial: respeitar os animais pode ser um bom negócio?
Authors: Souza Maria Cecília Galli Lugnani , Casotti Letícia Moreira , Lemme Celso Funcia
Published: December 2013

DOI: 10.5902/198346599022 The main objective of this study was to understand consumer behavior regarding cruelty against animals, practiced in industrial processes of meat production. The study used quantitative methodology, with a survey over the internet that was illustrated by a video showing some industrial practice on animal growing, such as little space and amputation of some limbs, which cause pain, fear and stress. Besides trying to evaluate the level of knowledge that consumers have about these procedures, the research intended to identify the potential for consuming habit changes as results of the contact with the new information. The study shows that consumers are not aware of the current meat producing standards. After having access to the industrial farms images, they change their perception, which may raise a threat to companies that keep current business models ignoring the claim for animal welfare.  In addition to that, they show themselves to be willing to pay higher prices for certified products, indicating the companies the existence of a steady market opportunity.
O processo de aquisição como estratégia organizacional gerar vantagem competitiva: um estudo de caso no mercado brasileiro de distribuição de combustíveis
Authors: Pereira Maurício Fernandes , Oliveira Fernando Ventura de
Published: December 2013

DOI: 10.5902/198346599170The subject from this work is about acquisitions as organizational strategies and it is guided by the general objective on identifying if the acquisition of Texaco by Ultra Group, in Brazil, could generate competitive advantages. Thus, the main aim is to characterize, specifically, the fuel distribution sector in Brazil, presenting characteristics, strategies, classification of resources and the competitive advantage’s identification in the buying process of Texaco by Ultra Group. The methodology used for this research is a case study of qualitative nature. Data collection has been performed through literature review, documentary analysis and semi-structured interviews. In the analysis of collected data, specific objectives have been met. It was clear, therefore, the presence of features such as scale earnings, brand exposure, better management practices, synergies, tangible and intangible assets and market growth. So, those resources are classified according to the competitive implications. Then, it might be concluded that Texaco´s acquisition could bring competitive advantages for Ultra / Ipiranga Group. Respondents believe the sector is growing and businesses tend to grow despite the world crisis. They also confirmed that, in a highly competitive market, strategic alliances and market growing are factors that may ensure success to each company.
L’intérêt scientifique d’une démarche participative
Authors: Le Méner Erwan , Oppenchaim Nicolas
Published: December 2013

Cet article propose d’évaluer les bienfaits et les inconvénients d’une démarche d’enquête participative. Il s’appuie sur le compte rendu d’une recherche par questionnaire auprès de familles sans logement. En cours de construction de l’enquête, des personnes anciennement dans cette situation ont rejoint l’équipe de recherche et contribué à l’élaboration comme à la passation du questionnaire. Cette expérience suggère que des recherches classiques pourraient avoir avantage à mettre en oeuvre des démarches participatives pour enrichir la connaissance scientifique.
Quantitative Methods in Participatory Research
Authors: Macaulay Ann C. , Jagosh Justin , Pluye Pierre , Bush Paula L. , Salsberg Jon
Published: December 2013

In this paper, we suggest that participatory research (PR) is neither a research methodology, nor uniquely associated with qualitative methods, but rather an approach to research through which stakeholders can implement quantitative, qualitative or mixed methods study designs. By illustrating three partnerships retained in our recent systematic review of PR, we highlight issues involved in partnered quantitative research. Examples demonstrate that commitment to dialogue and consensus building among partnership stakeholders is key to ensuring that methods generate scientifically valid research without creating community harm, loss of reputation, stigma or without generating feelings of denial, betrayal and exclusion.
Le social case work richmondien, entre clinique, démocratie et pragmatisme
Authors: Gravière Lilian
Published: December 2013

Cet article propose de reconsidérer les croyances démocratiques de Mary E. Richmond, fondatrice du social case work, l’un des premiers paradigmes du travail social. Ce dernier est une clinique répondant à des exigences participatives. Enfin l’article explore des pistes de comparaison entre le social case work et le pragmatisme deweyien.
Expériences connues, vécues… mais rarement écrites
Authors: Ouattara Fatoumata , Ridde Valéry
Published: December 2013

Cet article propose et poursuit l’analyse réflexive engagée par les sciences sociales sur les relations de collaboration entre les chercheurs du Nord et du Sud. Il s’agit notamment d’appréhender des rapports de partenariat à l’aune de situations en amont de la constitution formelle des cadres d’échanges « scientifiques ». Dans cette perspective, la défaillance progressive de la formation scientifique au Sud, conjuguée à des réseaux de clientélisme soutenus et entretenus par les collaborateurs du Nord et du Sud, ne favorise pas l’émergence de rapports de partenariats équitables. Si l’on considère le partenariat comme une construction, voire un processus, alors toute analyse sur le sujet devrait davantage s’intéresser aux énoncés explicites ainsi qu’aux non-dits qui colorent son inscription dans les relations de collaboration.
Deep crustal earthquakes in North Tanzania, East Africa: Interplay between tectonic and magmatic processes in an incipient rift
Authors: Albaric Julie , Déverchère Jacques , Perrot Julie , Jakovlev Andrey , Deschamps Anne
Published: December 2013

In this study, we explore the origin of lower crustal seismicity and the factors controlling rift propagation using seismological data recorded within the youngest part of the East African Rift System, the North Tanzanian Divergence (NTD). Most earthquakes below Lake Manyara occur at depth ranging between 20 and 40 km and have a swarm‐like distribution. Focal mechanisms of 26 events indicate a combination of strike‐slip and normal faulting involving Archaean basement structures and forming a relay zone. The derived local stress regime is transtensive and the minimum principal stress is oriented N110°E. Crustal seismic tomography reveals low‐velocity anomalies below the rifted basins in the NTD, interpreted as localized thermomechanical perturbations promoting fluid release and subsequent seismicity in the lower crust. SKS splitting analysis in the NTD indicates seismic anisotropy beneath 17 stations most likely due to aligned magma lenses and/or dikes beneath the rift and to the lithospheric fabrics. Our results favor a strain pattern intermediate between purely mechanical and purely magmatic. We suggest that melt products arising from a large asthenospheric thermal anomaly enhance lithospheric weakening and facilitate faulting and creeping on critically oriented inherited structures of the Precambrian lower crust. Although the crust is unlikely weakened at a point comparable to other parts of the East African Rift System, this deep‐seated thermomechanical process is efficient enough to allow slow rift propagation within the eastern Tanzanian cratonic edge.
Response of atmospheric CO2 to the abrupt cooling event 8200 years ago
Authors: Ahn Jinho , Brook Edward J. , Buizert Christo
Published: December 2013

Atmospheric CO2 records for the centennial scale cooling event 8200 years ago (8.2 ka event) may help us understand climate‐carbon cycle feedbacks under interglacial conditions, which are important for understanding future climate, but existing records do not provide enough detail. Here we present a new CO2 record from the Siple Dome ice core, Antarctica, that covers 7.4–9.0 ka with 8 to 16 year resolution. We observe a small, about 1–2 ppm, increase of atmospheric CO2 during the 8.2 ka event. The increase is not significant when compared to other centennial variations in the Holocene that are not linked to large temperature changes. Our results do not agree with leaf stomata records that suggest a CO2 decrease of up to ~25 ppm and imply that the sensitivity of atmospheric CO2 to the primarily Northern Hemisphere cooling of the 8.2 ka event was limited.
Is climate sensitivity related to dynamical sensitivity? A Southern Hemisphere perspective
Authors: Grise Kevin M. , Polvani Lorenzo M.
Published: December 2013

This study examines whether the spread in the climate sensitivity of Coupled Model Intercomparison Project Phase 5 (CMIP5) models also captures the spread in the Southern Hemisphere dynamical response to greenhouse gas forcing. Three metrics are proposed to quantify the “dynamical sensitivity” of the Southern Hemisphere: the poleward expansion of the Hadley circulation, the poleward expansion of the subtropical dry zone, and the poleward shift of the midlatitude jet. In the CMIP5 abrupt 4 × CO2 integrations, the expansion of the Hadley circulation is well correlated with climate sensitivity in all seasons; in contrast, the shifts in the subtropical dry zone and midlatitude jet are significantly correlated with climate sensitivity only in summer and fall. In winter, those responses are more strongly linked to the control climatology in each model. Thus, a narrow focus on traditional climate sensitivity alone might miss out on important features of the atmospheric circulation's response to increasing greenhouse gases, particularly in the extratropics.
Modeling of the O+pickup ion sputtering efficiency dependence on solar wind conditions for the Martian atmosphere
Authors: Wang Yung‐Ching , Luhmann Janet G. , Leblanc François , Fang Xiaohua , Johnson Robert E. , Ma Yingjuan , Ip Wing‐Huen , Li Lei
Published: December 2013

Sputtering of the Martian atmosphere by O+pickup ions has been proposed as a potentially important process in the early evolution of the Martian atmosphere. In preparation for the Mars Atmosphere and Volatile Evolution (MAVEN) mission, we performed a study using a Monte Carlo model coupled to a molecular dynamic calculation to investigate the cascade sputtering effects in the region of the Martian exobase. Pickup ion fluxes based on test particle simulations in an MHD model for three different solar wind conditions are used to examine the local and global sputtering efficiencies. The resultant sputtering escape rate is 2×1024 s−1at nominal solar wind condition and can be enhanced about 50 times when both the interplanetary magnetic field (IMF) strength and the solar wind pressure increase. It is found that when the IMF strength becomes stronger, both the pickup ion precipitation energies and the resultant sputtering efficiencies increase. The related escape flux, hot component, and atmospheric energy deposition deduced from the MAVEN measurements may reveal clues about the prominent enhanced sputtering effects. Significant hemispheric asymmetries can be observed related to the solar wind electric fields. The shielding by the crustal fields and the recycling onto the nightside due to different magnetic field draping features can also lead to regional variations of sputtering efficiencies. The results suggest that disturbed or enhanced solar wind conditions provide the best prospects for detecting sputtering effects for MAVEN mission.
Silica–Gold Core–Shell Nanosphere for Ultrafast Dynamic Nanothermometer
Authors: Sun Hongtao , Sun Xiang , Yu Mingpeng , Mishra Ashish Kumar , Huang Liping , Lian Jie
Published: December 2013

Effective temperature measurements are of significance for a fundamental understanding of nanosystems and functional applications, requiring ultimate miniaturization of thermometers with reduced size but maintained sensitivity, simplicity, and accuracy of temperature reading. Grand challenges exist for scenarios of thermal shock or combustion where materials may be subjected to extreme thermal flux and drastic temperature variations, and dynamic thermal sensors with an ultrafast response are yet to be developed. Here, an innovative design of silica–gold core–shell (SiO2@Au) nanospheres is demonstrated as a potential dynamic sensor with a sub‐second response time and accurate temperature determination based on the strong temperature dependence of the thermally induced morphological self‐reorganization and characteristic surface plasmon (SP) absorption of the metal shell. The irreversible thermally induced morphological and optical signatures behave as characteristic “fingerprints” for temperature recordings, allowing the retrieval of thermal history ex‐situ. As compared with current nanothermometer technologies such as metal‐filled nanotubes, the core–shell nanosphere‐based dynamic thermosensor offers synergistic advantages of ultrafast time response, fast readout, permanent recording of thermal history, and ex‐situ capabilities for effective temperature measurements.
A novel rheometer design for yield stress fluids
Authors: Samaniuk Joseph R. , Shay Timothy W. , Root Thatcher W. , Klingenberg Daniel J. , Scott C. Tim
Published: December 2013

An inexpensive, rapid method for measuring the rheological properties of yield stress fluids is described and tested. The method uses an auger that does not rotate during measurements, and avoids material and instrument‐related difficulties, for example, wall slip and the presence of large particles, associated with yield stress fluids. The method can be used for many types of yield stress fluids, including concentrated lignocellulosic biomass. Sample preparation prior to measurement is minimal, reducing, or eliminating disruption of the sample. We show that measurements using this technique compare well with measurements obtained with a vane rheometer. A variation of the described method is proposed that would make it easier to measure time‐dependent rheological properties. © 2014 American Institute of Chemical Engineers AIChE J, 60: 1523–1528, 2014
Ein Chaperonin als Protein‐Nanoreaktor für die radikalische Atomtransferpolymerisation
Authors: Renggli Kasper , Nussbaumer Martin G. , Urbani Raphael , Pfohl Thomas , Bruns Nico
Published: December 2013

Das Gruppe‐II‐Chaperonin Thermosom (THS) des Archaeons Thermoplasma acidophilum wurde als Nanoreaktor für die radikalische Atomtransferpolymerisation (ATRP) verwendet. Ein Kupfer‐Katalysator wurde ins Innere des THS eingeschlossen, um die Polymerisation in den Hohlraum des Proteinkäfigs zu beschränken. THS besitzt Poren, die groß genug sind, die gebildeten Polymere in die umgebende Lösung abzugeben. Der nanoskalige Reaktionsraum im Protein hat einen vorteilhaften Effekt auf die Polymerisation von N‐Isopropylacrylamid und Poly(ethylenglycol)methylether‐Acrylat. Eng verteilte Polymere mit Polydispersitätsindices (PDIs) von minimal 1.06 wurden erhalten, während Kontrollreaktionen mit einem globulären Protein‐Katalysator‐Konjugat lediglich Polymere mit PDIs von über 1.84 ergaben.
Crystallization of DNA‐Capped Gold Nanoparticles in High‐Concentration, Divalent Salt Environments
Authors: Tan Shawn J. , Kahn Jason S. , Derrien Thomas L. , Campolongo Michael J. , Zhao Mervin , Smilgies Detlef‐M. , Luo Dan
Published: December 2013

The multiparametric nature of nanoparticle self‐assembly makes it challenging to circumvent the instabilities that lead to aggregation and achieve crystallization under extreme conditions. By using non‐base‐pairing DNA as a model ligand instead of the typical base‐pairing design for programmability, long‐range 2D DNA–gold nanoparticle crystals can be obtained at extremely high salt concentrations and in a divalent salt environment. The interparticle spacings in these 2D nanoparticle crystals can be engineered and further tuned based on an empirical model incorporating the parameters of ligand length and ionic strength.
Diastereoselektive Synthese von offenkettigen sekundären Alkyllithiumverbindungen und Abfangreaktionen mit Elektrophilen
Authors: Dagousset Guillaume , Moriya Kohei , Mose Rasmus , Berionni Guillaume , Karaghiosoff Konstantin , Knochel Paul
Published: December 2013

Ein praktischer stereoselektiver Iod‐Lithium‐Austausch ermöglicht erstmals die Synthese von funktionalisierten stereodefinierten acyclischen sekundären nicht‐stabilisierten Lithiumreagentien aus den entsprechenden sekundären Alkyliodiden. Diese Lithiumreagentien reagieren mit verschiedenen Elektrophilen, einschließlich Kohlenstoff‐Elektrophilen, unter hoher Retention der Konfiguration. Kinetische Daten zur konfigurationellen Stabilität dieser acyclischen Alkyllithiumreagentien werden präsentiert. Die Methode bietet einen neuen, allgemeinen Zugang zu chiralen Synthons für die stereoselektive Synthese von offenkettigen Molekülen.
Extraction of (9,8) Single‐Walled Carbon Nanotubes by Fluorene‐Based Polymers
Authors: Si Rongmei , Wei Li , Wang Hong , Su Dingdian , Mushrif Samir H. , Chen Yuan
Published: December 2013

Selective polymer wrapping is a promising approach to obtain high‐chiral‐purity single‐walled carbon nanotubes (SWCNTs) needed in technical applications and scientific studies. We showed that among three fluorene‐based polymers with different side‐chain lengths and backbones, poly[(9,9‐dihexylfluorenyl‐2,7‐diyl)‐co‐(9,10‐anthracene)] (PFH‐A) can selectively extract SWCNTs synthesized from the CoSO4/SiO2 catalyst, which results in enrichment of 78.3 % (9,8) and 12.2 % (9,7) nanotubes among all semiconducting species. These high‐chiral‐purity SWCNTs may find potential applications in electronics, optoelectronics, and photovoltaics. Furthermore, molecular dynamics simulations suggest that the extraction selectivity of PFH‐A relates to the bending and alignment of its alkyl chains and the twisting of its two aromatic backbone units (biphenyl and anthracene) relative to SWCNTs. The strong π–π interaction between polymers and SWCNTs would increase the extraction yield, but it is not beneficial for chiral selectivity. Our findings suggest that the matching between the curvature of SWCNTs and the flexibility of the polymer side chains and the aromatic backbone units is essential in designing novel polymers for selective extraction of (n,m) species.
Almost Asymptotic Regulation of Markovian Jumping Linear Systems in Discrete Time
Authors: He Shu‐ping , Ding Zheng‐tao , Liu Fei
Published: December 2013

This paper considers the problems of almost asymptotic output regulation for discrete‐time Markovian jumping linear systems. Based on a stochastic Lyapunov‐Krasovskii functional framework, sufficient conditions for the extension of the regulation scheme to such stochastic systems are obtained via state feedback and via error feedback. Relying on a characterization of the feedback controllers, the almost asymptotic regulation is accomplished. The problem of guaranteeing stochastic stability and almost asymptotic tracking is achieved by solving linear matrix inequalities subject to a set of linear equality constraints. In order to ensure relaxed solutions of the regulation equations, a semi‐definite optimization approach via disciplined convex programming is outlined. Simulation results also are given to illustrate the effectiveness of the proposed design approach.
Ligand entry into the calyx of β‐lactoglobulin
Authors: Bello Martiniano , García‐Hernández Enrique
Published: December 2013

Although the thermodynamic principles that control the binding of drug molecules to their protein targets are well understood, the detailed process of how a ligand reaches a protein binding site has been an intriguing question over decades. The short time interval between the encounter between a ligand and its receptor to the formation of the stable complex has prevented experimental observations. Bovine β‐lactoglobulin (βlg) is a lipocalin member that carries fatty acids (FAs) and other lipids in the cellular environment. Βlg accommodates a FA molecule in its highly hydrophobic cavity and exhibits the capability of recognizing a wide variety of hydrophobic ligands. To elucidate the ligand entry process on βlg, we report molecular dynamics simulations of the encounter between palmitate (PA) or laurate (LA) and βlg. Our results show that residues localized in loops at the cavity entrance play an important role in the ligand penetration process. Analysis of the short‐term interaction energies show that the forces operating on the systems lead to average conformations very close to the crystallographic holo‐forms. Whereas the binding free energy analysis using the molecular mechanics Generalized Born surface area method shows that these conformations were thermodynamically favorable. © 2013 Wiley Periodicals, Inc. Biopolymers 101: 744–757, 2014.
A sensitive LC‐MS/MS method for simultaneous determination of R‐bambuterol and its active metabolite R‐terbutaline in human plasma and urine with application to a clinical pharmacokinetic study
Authors: Zhou Ting , Zhao Ting , Cheng Qing , Liu Shan , Xu Ling , Tan Wen
Published: December 2013

A sensitive liquid chromatography–tandem mass spectrometry (LC‐MS/MS) method for simultaneous determination of R‐bambuterol and its active metabolite R‐terbutaline in human plasma and urine was established. The inhibition for the biotransformation of R‐bambuterol in plasma was fully investigated. Plasma samples were prepared on ice and neostigmine metilsulfate added as a cholinesterase inhibitor immediately after sample collection. All samples were extracted with ethyl acetate and separated on a C18 column under gradient elution with a mobile phase consisting of methanol and water containing 5 mm ammonium acetate at a flow rate of 0.6 mL/min. The analytes were detected by an API 4000 tandem mass spectrometer with positive electrospray ionization in multiple reaction monitoring mode. The established method was highly sensitive with the lower limit of quantification (LLOQ) of 10.00 pg/mL for each analyte in plasma. In urine samples, the LLOQs were 20.00 and 500.0 pg/mL for R‐bambuterol and R‐terbutaline, respectively. The intra‐ and inter‐day precisions were <12.7 and <8.6% for plasma and urine, respectively. The analytical runtime within 6.0 min per sample made this method suitable for high‐throughput determination. The validated method has been successfully applied to the human pharmacokinetic study of R‐bambuterol involving 10 healthy volunteers. Copyright © 2013 John Wiley & Sons, Ltd.
A multivariate calibration procedure for UV/VIS spectrometric monitoring of BHK‐21 cell metabolism and growth
Authors: Leme Jaci , Fernández Núñez Eutimio Gustavo , de Almeida Parizotto Letícia , Chagas Wagner Antonio , dos Santos Erica Salla , Caricati Aline Tojeira Prestia , de Rezende Alexandre Gonçalves , da Costa Bruno Labate Vale , Monteiro Daniela Cristina Ventini , Boldorini Vera Lucia Lopes , Jorge Soraia Attie Calil , Astray Renato Mancini , Pereira Carlos Augusto , Caricati Celso Pereira , Tonso Aldo
Published: December 2013

Monitoring mammalian cell culture with UV–vis spectroscopy has not been widely explored. The aim of this work was to calibrate Partial Least Squares (PLS) models from off‐line UV–vis spectral data in order to predict some nutrients and metabolites, as well as viable cell concentrations for mammalian cell bioprocess using phenol red in culture medium. The BHK‐21 cell line was used as a mammalian cell model. Spectra of samples taken from batches performed at different dissolved oxygen concentrations (10, 30, 50, and 70% air saturation), in two bioreactor configurations and with two strategies to control pH were used to calibrate and validate PLS models. Glutamine, glutamate, glucose, and lactate concentrations were suitably predicted by means of this strategy. Especially for glutamine and glucose concentrations, the prediction error averages were lower than 0.50 ± 0.10 mM and 2.21 ± 0.16 mM, respectively. These values are comparable with those previously reported using near infrared and Raman spectroscopy in conjunction with PLS. However, viable cell concentration models need to be improved. The present work allows for UV–vis at‐line sensor development, decrease cost related to nutrients and metabolite quantifications and establishment of fed‐batch feeding schemes. © 2013 American Institute of Chemical Engineers Biotechnol. Prog., 30:241–248, 2014
CGTase‐Catalysed cis‐Glucosylation of L‐Rhamnosides for the Preparation of Shigella flexneri 2a and 3a Haptens
Authors: Urbach Carole , Halila Sami , Guerreiro Catherine , Driguez Hugues , Mulard Laurence A. , Armand Sylvie
Published: December 2013

We report the enzymatic synthesis of α‐D‐glucopyranosyl‐(1→4)‐α‐L‐rhamnopyranoside and α‐D‐glucopyranosyl‐(1→3)‐α‐L‐rhamnopyranoside by using a wild‐type transglucosidase in combination with glucoamylase and glucose oxidase. It was shown that Bacillus circulans 251 cyclodextrin glucanotransferase (CGTase, EC 2.1.4.19) can efficiently couple an α‐L‐rhamnosyl acceptor to a maltodextrin molecule with an α‐(1→4) linkage, albeit in mixture with the α‐(1→3) regioisomer, thus giving two glucosylated acceptors in a single reaction. Optimisation of the CGTase coupling reaction with β‐cyclodextrin as the donor substrate and methyl or allyl α‐L‐rhamnopyranoside as acceptors resulted in good conversion yields (42–70 %) with adjustable glycosylation regioselectivity. Moreover, the efficient chemical conversion of the products of CGTase‐mediated cis‐glucosylation into protected building blocks (previously used in the synthesis of O‐antigen fragments of several Shigella flexneri serotypes) was substantiated. These novel chemoenzymatic strategies towards useful, convenient intermediates in the synthesis of S. flexneri serotypes 2a and 3a oligosaccharides might find applications in developments towards synthetic carbohydrate‐based vaccine candidates against bacillary dysentery.
A General Method for Artificial Metalloenzyme Formation through Strain‐Promoted Azide–Alkyne Cycloaddition
Authors: Yang Hao , Srivastava Poonam , Zhang Chen , Lewis Jared C.
Published: December 2013

Strain‐promoted azide–alkyne cycloaddition (SPAAC) can be used to generate artificial metalloenzymes (ArMs) from scaffold proteins containing a p‐azido‐L‐phenylalanine (Az) residue and catalytically active bicyclononyne‐substituted metal complexes. The high efficiency of this reaction allows rapid ArM formation when using Az residues within the scaffold protein in the presence of cysteine residues or various reactive components of cellular lysate. In general, cofactor‐based ArM formation allows the use of any desired metal complex to build unique inorganic protein materials. SPAAC covalent linkage further decouples the native function of the scaffold from the installation process because it is not affected by native amino acid residues; as long as an Az residue can be incorporated, an ArM can be generated. We have demonstrated the scope of this method with respect to both the scaffold and cofactor components and established that the dirhodium ArMs generated can catalyze the decomposition of diazo compounds and both SiH and olefin insertion reactions involving these carbene precursors.
Aqueous Oxidative Heck Reaction as a Protein‐Labeling Strategy
Authors: Ourailidou Maria Eleni , van der Meer Jan‐Ytzen , Baas Bert‐Jan , Jeronimus‐Stratingh Margot , Gottumukkala Aditya L. , Poelarends Gerrit J. , Minnaard Adriaan J. , Dekker Frank J.
Published: December 2013

An increasing number of chemical reactions are being employed for bio‐orthogonal ligation of detection labels to protein‐bound functional groups. Several of these strategies, however, are limited in their application to pure proteins and are ineffective in complex biological samples such as cell lysates. Here we present the palladium‐catalyzed oxidative Heck reaction as a new and robust bio‐orthogonal strategy for linking functionalized arylboronic acids to protein‐bound alkenes in high yields and with excellent chemoselectivity even in the presence of complex protein mixtures from living cells. Advantageously, this reaction proceeds under aerobic conditions, whereas most other metal‐catalyzed reactions require inert atmosphere.
Redox‐Based Resistive Switching Memories (ReRAMs): Electrochemical Systems at the Atomic Scale
Authors: Valov Ilia
Published: December 2013

Resistive switching memories (RRAMs) are an emerging research field, which is currently of focused interest for both the interdisciplinary scientific community and industry. RRAMs are nano‐electrochemical systems with great potential as a disruptive technology for the semiconductor industry as well as for a number of applications such as memory, logic and analog circuits, memristive operations, neuromorphic applications and computing. The present review aims to present the current state‐of‐the‐art knowledge on redox‐based resistive switching RRAMs, highlighting the role of the interfaces, discussing the electrochemical kinetics during formation of nanofilaments, and to relate them to the more fundamental issue of microscopic description of electrochemical processes at the atomic scale.
The Relationship between DNA Sequences and Oligonucleotide‐Templated Silver Nanoclusters and Their Fluorescence Properties
Authors: Teng Ye , Yang Xuan , Han Lei , Wang Erkang
Published: December 2013

A novel approach was developed to study the relationship between DNA sequences and DNA‐templated silver nanoclusters (DNA‐Ag NCs) in detail by using an ordinary DNA strand as an example. Three kinds of Ag NCs are formed by using the DNA strand as a scaffold. By dividing the DNA template into several parts according to their different affinities to Ag+, it was found that the fluorescence properties of DNA‐Ag NCs are related to not only the sequences but also to the position of different parts in the template, which provides a more efficient approach to obtain DNA‐Ag NCs with required photoluminescence properties and may ultimately contribute to the targeted synthesis of DNA‐Ag NCs.
Enhancing CO2 Separation Ability of a Metal–Organic Framework by Post‐Synthetic Ligand Exchange with Flexible Aliphatic Carboxylates
Authors: Hong Dae Ho , Suh Myunghyun Paik
Published: December 2013

A series of porous metal–organic frameworks having flexible carboxylic acid pendants in their pores (UiO‐66‐ADn: n=4, 6, 8, and 10, where n denotes the number of carbons in a pendant) has been synthesized by post‐synthetic ligand exchange of terephthalate in UiO‐66 with a series of alkanedioic acids (HO2C(CH2)n−2CO2H). NMR, IR, PXRD, TEM, and mass spectral data have suggested that a terephthalate linker in UiO‐66 was substituted by two alkanedioate moieties, resulting in free carboxyl pendants in the pores. When post‐synthetically modified UiO‐66 was partially digested by adjusting the amount of added HF/sample, NMR spectra indicated that the ratio of alkanedioic acid/terephthalic acid was increased with smaller amounts of acid, implying that the ligand substitution proceeded from the outer layer of the particles. Gas sorption studies indicated that the surface areas and the pore volumes of all UiO‐66‐ADns were decreased compared to those of UiO‐66, and that the CO2 adsorption capacities of UiO‐66‐ADn (n=4, 8) were similar to that of UiO‐66. In the case of UiO‐66‐AD6, the CO2 uptake capacity was 34 % higher at 298 K and 58 % higher at 323 K compared to those of UiO‐66. It was elucidated by thermodynamic calculations that the introduction of flexible carboxyl pendants of appropriate length has two effects: 1) it increases the interaction enthalpy between the host framework and CO2 molecules, and 2) it mitigates the entropy loss upon CO2 adsorption due to the formation of multiple configurations for the interactions between carboxyl groups and CO2 molecules. The ideal adsorption solution theory (IAST) selectivity for CO2 adsorption over that of CH4 was enhanced for all of the UiO‐66‐ADns compared to that of UiO‐66 at 298 K. In particular, UiO‐66‐AD6 showed the most strongly enhanced CO2 uptake capacity and significantly increased selectivity for CO2 adsorption over that of CH4 at ambient temperature, suggesting that it is a promising material for sequestering CO2 from landfill gas.
Highly Selective and Responsive Visible to Near‐IR Ytterbium Emissive Probe for Monitoring Mercury(II)
Authors: Zhang Tao , Chan Chi‐Fai , Lan Rongfeng , Wong Wai‐Kwok , Wong Ka‐Leung
Published: December 2013

A new lanthanide probe based on the fluorescence resonance energy transfer (FRET) process with the combination of ytterbium porphyrinate complex and a rhodamine B derivative unit was synthesized to detect the Hg2+ ion with responsive emission in the visible and near‐IR region with a detection limit of 10 μM
Pd–Carbene Migratory Insertion: Application to the Synthesis of Trifluoromethylated Alkenes and Dienes
Authors: Wang Xi , Xu Yan , Deng Yifan , Zhou Yujing , Feng Jiajie , Ji Guojing , Zhang Yan , Wang Jianbo
Published: December 2013

Pd‐catalyzed cross‐coupling of halides with CF3‐substituted diazo compounds or N‐tosylhydrazones has been explored for the synthesis of CF3‐substituted alkenes and 1,3‐butadienes. Pd–carbene migratory insertion plays the key role in these transformations.
Ionic Liquids Supported on Metal‐Organic Frameworks: Remarkable Adsorbents for Adsorptive Desulfurization
Authors: Khan Nazmul Abedin , Hasan Zubair , Jhung Sung Hwa
Published: December 2013

Acidic ionic‐liquids (IL) supported on metal–organic frameworks (MOFs) have been shown to be beneficial for adsorptive desulfurization. A remarkable improvement in the adsorption capacity (ca. 71%) was observed in for ILs supported on MIL‐101 compared with virgin MIL‐101. The improved adsorptive performance might be explained by the acid–base interactions between the acidic ionic liquid and basic benzothiophene (BT). Moreover, from this study, it can be suggested that porous MOFs, supported with ionic liquids, may introduce a new class of highly porous adsorbents for the efficient adsorption of various compounds.
ChemInform Abstract: The Monoclinic Form of Trilithium Dichromium(III) Tris(orthophosphate).
Authors: Sun Joobin , Kim Pilsoo , Yun Hoseop
Published: December 2013

Monoclinic Li3Cr2(PO4)3 is prepared by melting equimolar amounts of Cr and P in a reactive LiCl/CsCl (4:1) flux (reactant/flux ratio of 1:3, evacuated silica tube, 1123 K, 2 d, 4 K/h cooling rate).
ChemInform Abstract: Cyclopentasilane Si5H10: First Single Crystal X‐Ray Structure of an Oligosilane SixHy and Thermal Analysis with TG/MS.
Authors: Schmidt Dana , Boehme Uwe , Seidel Juergen , Kroke Edwin
Published: December 2013

Cyclopentasilane Si5H10 single crystals are grown in situ from liquid Si5H10 (repeated melting and freezing between 263 and 153 K) allowing the XRD structure determination at 173 K.
ChemInform Abstract: Structure and Chemical Bonding of ScNiB4.
Authors: Eickerling Georg , Scherer Wolfgang , Fickenscher Thomas , Rodewald Ute Ch. , Poettgen Rainer
Published: December 2013

ScNiB4 is prepared by arc melting of stoichiometric mixtures of the elements followed by annealing slightly below the melting point for the growth of single crystals.
ChemInform Abstract: Synthesis and Structural and Magnetic Characterization of the Frustrated Magnetic System La2Ni4/3‐xCoxSb2/3O6.
Authors: Franco D. G. , Carbonio R. E. , Nieva G.
Published: December 2013

The title double perovskites (x = 0, 1/3, 2/3, 1) are prepared by solid state reactions of stoichiometric mixtures of La2O3, NiO, Co3O4, and Sb2O3 (950 and 1400 °C, 12 h each).
ChemInform Abstract: Local Environments of Dilute Activator Ions in the Solid‐State Lighting Phosphor Y3‐xCexAl5O12.
Authors: George Nathan C. , Pell Andrew J. , Dantelle Geraldine , Page Katharine , Llobet Anna , Balasubramanian M. , Pintacuda Guido , Chmelka Bradley F. , Seshadri Ram
Published: December 2013

Ce‐doped yttrium aluminum garnet (Ce:YAG), CexY3‐xAl5O12 with x = 0—0.09, is prepared by solid state synthesis using stoichiometric amounts of Y2O3, Al2O3, and CeO2 plus an optimum of 5 wt% each of BaF2 and NH4F as sintering aids (alumina crucible, 1500 °C, 5 h, 5% H2/N2 atmosphere).
ChemInform Abstract: On the Control Parameters of the Quasi‐One Dimensional Superconductivity in Sc3CoC4.
Authors: Eickerling Georg , et al. et al.
Published: December 2013

A detailed analysis of structural, electronic, and vibrational properties of the low‐temperature phase of Sc3CoC4, which is one of a few well‐documented quasi one‐dimensional superconductors, is presented.
ChemInform Abstract: CoxCu1‐xCr2S4 Nanocrystals: Synthesis, Magnetism, and Band Structure Calculations.
Authors: Ramasamy Karthik , Sims Hunter , Gupta Ram K. , Kumar Dhananjay , Butler William H. , Gupta Arunava
Published: December 2013

Nanocrystals of CoxCu1‐xCr2S4 are prepared over the entire composition range by reaction of appropriate amounts of CuCl2, CoCl2, and CrCl3 in the presence of octadecylamine (360 °C, N2 atmosphere) followed by injection of 1‐dodecanethiol and further heating for 1 h.
ChemInform Abstract: Divalent Iron Nitridophosphates: A New Class of Cathode Materials for Li‐Ion Batteries.
Authors: Liu Jue , Yu Xiqian , Hu Enyuan , Nam Kyung‐Wan , Yang Xiao‐Qing , Khalifah Peter G.
Published: December 2013

Na2Fe2P3O9N is prepared by reaction of NaPO3, Fe2O3, and (NH4)2HPO4 in a NH3 stream (quartz boat, 625 °C, 40 h).
ChemInform Abstract: Cobalt Molybdenum Oxynitrides: Synthesis, Structural Characterization, and Catalytic Activity for the Oxygen Reduction Reaction.
Authors: Cao Bingfei , Veith Gabriel M. , Diaz Rosa E. , Liu Jue , Stach Eric A. , Adzic Radoslav R. , Khalifah Peter G.
Published: December 2013

Carbon supported cobalt molybdenum oxynitrides, CoxMo1‐xOyNz/C (x = 0.25, 0.50, 0.75) are prepared from aqueous solutions of Co(NO3)2, (NH4)6Mo7O24, and carbon black followed by ammonolysis of the obtained powders at 773—973 K for 3 h.
ChemInform Abstract: Synthesis of Large Single Crystals and Thermoelectrical Properties of the Type‐I Clathrate K8Zn4Sn42.
Authors: Baran Volodymyr , Fischer Andreas , Scherer Wolfgang , Faessler Thomas F.
Published: December 2013

Large single crystals of K8Zn4Sn42 with a length of up to 6 mm are prepared from a mixture of the elements using excess Sn as a flux (Ta ampule, 650 °C, 1 h).
ChemInform Abstract: A New Polyanion with Dawson‐Like Constitution: [H2SeW18O60]6‐.
Authors: Wang Lijuan , Li Wenjuan , Wu Lizhou , Dong Xinbo , Hu Huaiming , Xue Ganglin
Published: December 2013

The tungstoselenite (Et2NH2)6 [H2SeW18O60] is prepared by reaction of Na2WO4, Na2SeO3, and Et2NH2Cl in the presence of KCl and Fe(NO3)3 under acidic conditions (H2O, pH 1.7 adjusted with HCl, 25 °C, 5 min; 18% yield).
ChemInform Abstract: The Flexible Ba7UM2S12.5O0.5 (M: V, Fe) Compounds: Syntheses, Structures and Spectroscopic, Resistivity, and Electronic Properties.
Authors: Mesbah Adel , Stojko Wojciech , Malliakas Christos D. , Lebegue Sebastien , Clavier Nicolas , Ibers James A.
Published: December 2013

The new compounds Ba7UV2S12.5O0.5 (I) and Ba7UFe2S12.5O0.5 (II) are prepared by solid state reaction of BaS, V or Fe, U, and S (evacuated carbon‐coated silica tubes, 1223 K, 8 d, 50 and 90 wt.% yield, resp.).
ChemInform Abstract: Enantio‐ and Regioselective Conjugate Addition of Organometallic Reagents to Linear Polyconjugated Nitroolefins.
Authors: Tissot Matthieu , Alexakis Alexandre
Published: December 2013

The copper‐catalyzed addition of trialkylaluminum reagents to polyconjugated olefins using a ferrocene‐based phosphine ligand affords selectively 1,4‐addition products with high enantioselectivity.
ChemInform Abstract: Iron‐Catalyzed Asymmetric Haloamination Reactions.
Authors: Cai Yunfei , Liu Xiaohua , Zhou Pengfei , Kuang Yulong , Lin Lili , Feng Xiaoming
Published: December 2013

An asymmetric chloroamination of 3‐alkylidene‐ and 3‐arylidene‐indolin‐2‐ones (I) is developed affording the corresponding chiral oxindole derivatives (III) bearing vicinal anti‐chloroamine substituents.
ChemInform Abstract: Amphiphilic Methyleneamino Synthon Through Organic Dye Catalyzed‐Decarboxylative Aminoalkylation.
Authors: Chen Li , Chao Chin Sheng , Pan Yuanhang , Dong Sheng , Teo Yew Chin , Wang Jian , Tan Choon‐Hong
Published: December 2013

N‐Aryl amino acids (I) are used as precursors for photo‐induced synthons, which are coupled with a radical or a nucleophile to afford a variety of natural product‐like compounds.
ChemInform Abstract: A Palladacyclic Azobenzene Derivative as a Catalyst for Carbon—Carbon Bond Formation Reactions.
Authors: Bulygina L. A. , Khrushcheva N. S. , Peregudova S. M. , Sokolov V. I.
Published: December 2013

The bis‐chelated palladacycle is moderately active as catalyst for Suzuki and Heck reactions.
ChemInform Abstract: A Waste‐Minimized Protocol for the Preparation of 1,2‐Azido Alcohols and 1,2‐Amino Alcohols
Authors: Ballerini Eleonora , Crotti Paolo , Frau Ileana , Lanari Daniela , Pizzo Ferdinando , Vaccaro Luigi
Published: December 2013

via azidolysis of epoxides under solvent‐free conditions in the presence of a polystyrene‐supported bisfluoride DABCO catalyst
ChemInform Abstract: C‐5′‐Substituted Cinchona Alkaloid Derivatives Catalyse the First Highly Enantioselective Dynamic Kinetic Resolutions of Azlactones by Thiolysis.
Authors: Palacio Carole , Connon Stephen J.
Published: December 2013

Several cinchona‐derived catalysts are prepared and tested for this reaction.
ChemInform Abstract: Ligand‐Controlled Palladium‐Catalyzed Regiodivergent Suzuki—Miyaura Cross‐Coupling of Allylboronates and Aryl Halides.
Authors: Yang Yang , Buchwald Stephen L.
Published: December 2013

An orthogonal set of catalyst systems for the Suzuki—Miyaura coupling of 3,3‐disubstituted and 3‐monosubstituted allylboronates with aryl halides is developed.
ChemInform Abstract: Catalytic MBH Reaction of β‐Substituted Nitroalkenes with Azodicarboxylates.
Authors: Chen Xiang‐Yu , Xia Fei , Ye Song
Published: December 2013

The Morita—Baylis—Hillman reaction of nitroalkenes with azo‐dicarboxylates is optimized requiring only low loadings of a NHC‐precatalyst as promotor.