bluuebunny/crossref_metadata_2025 huggingface dataset:
Seasonal influence of snow conditions on Dall’s sheep productivity in Wrangell-St Elias National Park and Preserve
Authors: Cosgrove Christopher L. , Wells Jeff , Nolin Anne W. , Putera Judy , Prugh Laura R.
Published: February 2021

Dall’s sheep (Ovis dalli dalli) are endemic to alpine areas of sub-Arctic and Arctic northwest America and are an ungulate species of high economic and cultural importance. Populations have historically experienced large fluctuations in size, and studies have linked population declines to decreased productivity as a consequence of late-spring snow cover. However, it is not known how the seasonality of snow accumulation and characteristics such as depth and density may affect Dall’s sheep productivity. We examined relationships between snow and climate conditions and summer lamb production in Wrangell-St Elias National Park and Preserve, Alaska over a 37-year study period. To produce covariates pertaining to the quality of the snowpack, a spatially-explicit snow evolution model was forced with meteorological data from a gridded climate re-analysis from 1980 to 2017 and calibrated with ground-based snow surveys and validated by snow depth data from remote cameras. The best calibrated model produced an RMSE of 0.08 m (bias 0.06 m) for snow depth compared to the remote camera data. Observed lamb-to-ewe ratios from 19 summers of survey data were regressed against seasonally aggregated modelled snow and climate properties from the preceding snow season. We found that a multiple regression model of fall snow depth and fall air temperature explained 41% of the variance in lamb-to-ewe ratios (R2= .41, F(2,38) = 14.89, p<0.001), with decreased lamb production following deep snow conditions and colder fall temperatures. Our results suggest the early establishment and persistence of challenging snow conditions is more important than snow conditions immediately prior to and during lambing. These findings may help wildlife managers to better anticipate Dall’s sheep recruitment dynamics.
Hemodynamic determinants of left atrial strain in patients with hypertrophic cardiomyopathy: A combined echocardiography and CMR study
Authors: Tayal Bhupendar , Malahfji Maan , Buergler John M. , Shah Dipan J. , Nagueh Sherif F.
Published: February 2021

Background

Left atrial (LA) strain is associated with symptomatic status and atrial fibrillation in patients with hypertrophic cardiomyopathy (HCM). However, hemodynamic determinants of LA reservoir (LARS), conduit, and pump strains have not been examined and data are needed on the relation of LA strain with exercise tolerance in HCM.

Methods

Fifty HCM patients with echocardiographic and CMR imaging within 30 days were included. Left ventricular (LV) volumes, mass, EF, scar extent, extracellular volume fraction (ECV), and LA maximum volume were measured by CMR. Echo studies were analyzed for mitral inflow, pulmonary vein flow, mitral annulus tissue Doppler velocities, LV global longitudinal strain, and LA strain. Twenty six patients able and willing to exercise underwent cardiopulmonary stress testing for peak oxygen consumption (MVO2), and VE/VCO2 slope. Patients were followed for clinical events.

Findings

LARS was significantly associated with indices of LA systolic function, LV GLS, and LV filling pressures (P<0.05). Conduit strain was significantly associated with mitral annulus early diastolic velocity and ECV, whereas LA pump strain was determined by LA systolic function and indices of LV end diastolic pressure (all P<0.05). LARS and conduit strain were significantly higher in patients who achieved ≥80% of MVO2. LARS, conduit, and pump strains were significantly associated with atrial fibrillation (P<0.05).

Conclusions

LV structure, systolic and diastolic function, and LA systolic function determine the 3 components of LA strain. LA strain is associated with exercise tolerance and clinical events in patients with HCM.
Phylogenetic analysis of the distribution of deadly amatoxins among the little brown mushrooms of the genus Galerina
Authors: Landry Brandon , Whitton Jeannette , Bazzicalupo Anna L. , Ceska Oldriska , Berbee Mary L.
Published: February 2021

Some but not all of the species of ’little brown mushrooms’ in the genusGalerinacontain deadly amatoxins at concentrations equaling those in the death cap,Amanita phalloides. However,Galerina’s ~300 species are notoriously difficult to identify by morphology, and the identity of toxin-containing specimens has not been verified with DNA barcode sequencing. This left open the question of whichGalerinaspecies contain toxins and which do not. We selected specimens for toxin analysis using a preliminary phylogeny of the fungal DNA barcode region, the ribosomal internal transcribed spacer (ITS) region. Using liquid chromatography/mass spectrometry, we analyzed amatoxins from 70 samples ofGalerinaand close relatives, collected in western British Columbia, Canada. To put the presence of toxins into a phylogenetic context, we included the 70 samples in maximum likelihood analyses of 438 taxa, using ITS, RNA polymerase II second largest subunit gene (RPB2), and nuclear large subunit ribosomal RNA (LSU) gene sequences. We sequenced barcode DNA from types where possible to aid with applications of names. We detected amatoxins only in the 24 samples of theG.marginatas.l. complex in theNaucoriopsisclade. We delimited 56 putativeGalerinaspecies using Automatic Barcode Gap Detection software. Phylogenetic analysis showed moderate to strong support forGalerinainfrageneric cladesNaucoriopsis,Galerina,Tubariopsis, andSideroides.Mycenopsisappeared paraphyletic and includedGymnopilus. Amatoxins were not detected in 46 samples fromGalerinaclades outside ofNaucoriopsisor from outgroups. Our data show significant quantities of toxin in all mushrooms tested from theG.marginatas.l. complex. DNA barcoding revealed consistent accuracy in morphology-based identification of specimens toG.marginatas.l. complex. Prompt and careful morphological identification of ingestedG.marginatas.l. has the potential to improve patient outcomes by leading to fast and appropriate treatment.
Frequency and determinants of misuse of augmentation of labor in France: A population-based study
Authors: Girault Aude , Blondel Béatrice , Goffinet François , Le Ray Camille
Published: February 2021

Introduction

While use of augmentation of labor (AL) is appropriate for labor dystocia, it is frequently used inadequately and unnecessarily. The objective was to assess at a national level, the frequency and determinants of misuse of augmentation of labor (AL).

Material and methods

Women of the French perinatal survey of 2016 with a singleton cephalic fetus, delivering at term after a spontaneous labor were included. “Misuse of AL” was defined by artificial rupture of the membranes (ROM) and/or oxytocin within one hour of admission and/or duration between ROM and oxytocin of less than one hour. Women, labor and maternity unit’s characteristics were compared between the “misuse of AL” and “no misuse of AL” groups by bivariate analysis. To identify the determinants of misuse of AL, a multivariable multilevel logistic regression was performed taking into account the data’s hierarchical structure (first level: women, second level: maternity units).

Results

Among the 7196 women included, 1524 (21.2%) had a misuse of AL. The determinants of misuse of AL were middle school educational level (reference high school), aOR = 1.21; 95%CI[1.01–1.45], gestational age at delivery ≥41weeks (reference 39–40 weeks), aOR = 1.19; 95%CI[1.00–1.42], cervical dilation ≥6cm at admission (reference <3cm), aOR = 1.39; 95%CI[1.10–1.76], epidural analgesia aOR = 1.63; 95%CI[1.35–1.96], delivery in a private hospital (reference public teaching hospital), aOR = 2.25; 95%CI[1.57–3.23]; and maternity units with <1000 deliveries/year and 1000–1999 deliveries/year (reference ≥3000 deliveries/year), respectively aOR = 1.52; 95%CI[1.11–2.08] and aOR = 1.42; 95%CI[1.05–1.92]. Less than 3% of the variance was explained by women characteristics, and 24.17% by the maternity units’ characteristics.

Conclusions

In France, one spontaneous laboring woman among five is subject to misuse of AL. The misuse is mostly explained by maternity unit’s characteristics. The determinants identified in this study can be used to implement targeted actions in small and private maternity units.
Valorization of khat (Catha edulis) waste for the production of cellulose fibers and nanocrystals
Authors: Gabriel Tesfaye , Wondu Kebede , Dilebo Jemal
Published: February 2021

Cellulose fibers (C40 and C80) were extracted from khat (Catha edulis) waste (KW) with chlorine-free process using 40% formic acid/40% acetic acid (C40), and 80% formic acid/80% acetic acid (C80) at the pretreatment stage, followed by further delignification and bleaching stages. Cellulose nanocrystals (CNCs40 and CNCs80) were then isolated from C40 and C80 with sulfuric acid hydrolysis, respectively. Thus, the current study aims to isolate cellulose fibers and CNCs from KW as alternative source. The KW, cellulose fibers, and CNCs were investigated for yield, chemical composition, functionality, crystallinity, morphology, and thermal stability. CNCs were also evaluated for colloidal stability, particle size, and their influence on in vitro diclofenac sodium release from gel formulations preliminarily. The FTIR spectra analysis showed the removal of most hemicellulose and lignin from the cellulose fibers. The XRD results indicated that chemical pretreatments and acid hydrolysis significantly increased the crystallinity of cellulose fibers and CNCs. The cellulose fibers and CNCs exhibited Cellulose Iβ crystalline lattice. TEM analysis revealed formation of needle-shaped nanoscale rods (length: 101.55–162.96 nm; aspect ratio: 12.84–22.73). The hydrodynamic size, polydispersity index, and zeta potential of the CNCS ranged from 222.8–362.8 nm; 0.297–0.461, and -45.7 to -75.3 mV, respectively. CNCs40 exhibited superior properties to CNCs80 in terms of aspect ratio, and colloidal and thermal stability. Gel formulations containing high proportion of CNCs sustained diclofenac sodium release (< 50%/cm2) over 12 h. This study suggests that cellulose fibers and nanocrystals can be successfully obtained from abundant and unexploited source, KW for value-added industrial applications.
The impact of cataract progression on accuracy of intraocular lens power measurement
Authors: Leng Lin , Li Honglei , Yin Min , Gao Han , Shao Ting , Long Keli
Published: February 2021

Purpose

The aim of this study was to assess the impact of cataract progression using the Haigis formula-calculated intraocular lens (IOL) power and investigate the accuracy of IOL power measured at different time points.

Methods

This prospective study was performed on 75 eyes of 75 patients who underwent uneventful cataract surgery. Preoperative ocular parameters including axial length (AL), keratometry (K), anterior chamber depth (ACD), corneal astigmatism, corrected distance visual acuity (CDVA) and uncorrected distance visual acuity (UDVA) examined at the two time points, more than 3 months preoperatively and preoperative 1 day were compared. The ocular parameters measured in the two time points were used to calculate the predicted implanted IOL power and the actual IOL power was chosen on the basis of parameters measured earlier before surgery using the Haigis formula. The mean numerical error (MNE) and mean absolute error (MAE) predicted by the two time points were also compared.

Results

There were significant differences in the ACD, IOL power, UDVA and CDVA (P<0.01), but no statistical differences in AL, mean K and corneal astigmatism (P>0.05) during the average of 5.6 months before surgery. No statistically significant difference was detected in MNE (P>0.05), while the MAE had a significant difference in the two time points (P<0.05).

Conclusion

The IOL power measured earlier before surgery might result in a higher accuracy and the postoperative refractive outcome tended towards emmetropia.
Injury prevention: Individual factors affecting adult recreational snowboarders’ actual and estimated speeds on regular slopes
Authors: Carus Luis , Castillo Isabel
Published: February 2021

Speed is a main factor affecting the kinematic of snow-sports accidents and the degree of severity of the resulting injuries. The aim of this study was to measure on-slope actual maximum speeds of snowboarders and to assess their ability to accurately them with regard to individual factors such as gender, skill level, age and risk-taking behaviour and actual maximum speed. The data were obtained from a sample of 312 (67% male, 33% female) adult recreational snowboarders taking lessons in one of the major resorts in the Spanish Pyrenees. The Pearson correlation coefficient was used to investigate the relationship between maximal measured actual speed and estimated speed for all participants. Multiple linear regression analysis was used to estimate the impact of individual factors on both the snowboarders’ actual maximum speed and their error of estimation. The Pearson correlation coefficient between estimated and actual maximum speed was 0.52 (P < 0.001) for all participants. They underestimated their actual maximum speed on average by 10.05 km/h or 28.62%. All assessed factors were shown to significantly affect the snowboarders’ actual maximum speed. However, gender, skill level, age and actual maximum speed were shown to significantly affect the snowboarders’ error of estimation, while risk-taking behavior did not. Gender, skill level, age and risk-taking behaviour are associated with the actual maximum speed at which snowboarders ride, while the same individual factors, except for risk-taking behaviour, and their snowboarding speed seem to affect the ability to estimate actual maximum speeds in adult recreational snowboarders. The ability to estimate actual speed accurately is an important factor to avoid accidents on ski slopes and, therefore, having snowboarders informed about the benefits of speed self-awareness is a key matter for prevention purposes.
Contenido preventivo en la negociación colectiva
Authors: Poquet Catala Raquel
Published: February 2021

En este trabajo se realiza un análisis cualitativo y cuantitativo de los convenios colectivos de ámbito estatal de los dos últimos años y medio en cuanto a la regulación que contienen sobre la materia de seguridad y salud laboral. En este sentido, se procede a estudiar con detalle la regulación convencional sobre la formación, vigilancia de la salud, órganos de representación de los trabajadores, colectivos con protección especial y nuevos riesgos emergentes, en concreto, el acoso moral. Se concluye en general, que, desafortunadamente, y aunque se ha conseguido un avance importante al respecto, en los momentos actuales, y en general, la materia preventiva aún no ha tenido un adecuado reflejo en la negociación colectiva, ni siquiera en aquellos casos en los que la LPRL realiza un llamamiento expreso a la normativa convencional.  Es decir, los resultados de la negociación colectiva en esta materia no son suficientes, pues la mayoría de los convenios se remiten simplemente a la LPRL, mediante meras declaraciones retóricas sobre la importancia de la misma, sin proponer una regulación adecuada y sistemática de la misma y, más en concreto, de las peculiaridades y particularidades de su sector productivo, cuando la finalidad de los mismos es concretamente ello.
Fisioterapia graduko ikasleek desgaitasunekiko dituzten jarrerak unibertsitateko formazioan zehar
Authors: Saigos Ana , Ozamiz-Etxebarria Naiara , Ortiz Miren Agurtzane
Published: February 2021

Ikerketa honen helburua Euskal Herriko Unibertsitateko Fisioterapia Graduko lehen mailako eta laugarren mailako ikasleek desgaitasuna duten pertsonen aurrean duten jarrera aztertzea eta ebaluatzea izan da. Horretarako, desgaitasuna duten pertsonen aurrean agertzen diren jarrerei buruzko eskala bat erabili da, eta jarreretan eragin dezaketen zenbait faktore ere aztertu dira (adina, sexua eta desgaitasunarekin izandako kontaktua). Analisi estatistikoak burutu ondoren, emaitzek erakutsi dute bai lehen mailako, bai laugarren mailako ikasleek jarrera positiboa dutela. Ikusi da ere adinak eta des- gaitasunarekin kontaktua izateak jarrerak hobetzen dituztela. Bestalde, gizonen eta emakumeen jarreren artean ez da ezberdintasun nabarmenik aurkitu.
Agent organisations: from independent agents to virtual organisations and societies of agents
Authors: Maestro-Prieto Jose Alberto , Rodríguez Sara , Casado Roberto , Corchado Juan Manuel
Published: February 2021

Real world applications using agent-based solutions can include many agents that needs communicate and interact each other in order to meet their objectives. In open multi-agent systems, the problems may include the organisation of a large number of agents that may be heterogeneous, of unpredictable provenance and where competitive behaviours or conflicting objectives may occur. An overview of the alternatives for dealing with these problems is presented, highlighting the way they try to solve or mitigate these problems.
Postpartum perineal muscle sonogram in Madura beef cow
Authors: Hayanti Sari Yanti , Amrozi Amrozi , Aryogi Aryogi , Ulum Mokhamad Fakhrul
Published: February 2021

Background and Aim: Ultrasonography (USG) is useful for non-invasively identifying changes that occur in soft tissue architecture. The objective of this research was to demonstrate postpartum (PP) uterine involution through the changes of perineal muscle intensity and thickness in Madura beef cow by ultrasonography.

Materials and Methods: Madura's breed cows used in the research consist of eight non-pregnant (NP) cows and three PP cow. The transrectal and transperineal USG imaging of NP cows was performed on days 1, 33, and 65. USG imaging of PP cows was performed every day starting from day 1 (24 h after parturition) until day 21 PP. Transrectal USG of the reproductive tract was performed for the cervix, corpus uteri, and cornua uteri. USG was performed transcutaneously over the perineal area for coccygeus and levator ani muscles at the longitudinal and transverse angles. Reproductive tract diameter and perineal muscle intensity and thickness were measured with ultrasound imaging.

Results: The analysis of the sonogram of PP cows showed that the diameter of the cervix, corpus uteri, and cornua uteri decreased within 21 days PP. The transverse view of the coccygeus muscle of PP cows showed decreased muscle intensity and thickness. On the other hand, the longitudinal view showed increased coccygeus muscle intensity and thickness. The transverse view of the coccygeus muscle of NP cows showed increased muscle intensity, while muscle thickness was reduced. Sonogram analysis of the levator ani muscle of PP cows showed decreased muscle intensity with increasing muscle thickness. However, imaging of the levator ani muscle of NP cows showed a decrease in both intensity and muscle thickness. There was a significant difference in the mean value intensity of the scanning view analysis results of the levator ani muscle of the PP cow (523.6 AU increased to 672.1 AU) and the NP cow (515.9 AU decreased to 465.4 AU). Furthermore, there was a significant difference (p<0.05) in the mean value thickness of both scanning view analyses of the coccygeus and levator ani muscles of PP cows (5.8 mm increased to 6.5 mm and 3.8 mm increased to 4.8 mm, respectively) and NP cows (8.8 mm increased to 9.1 mm and 5.9 mm decreased to 4.9 mm, respectively).

Conclusion: We found that the perineal muscles, namely, the levator ani muscle and coccygeus muscle, change in size, and intensity during uterine involution as demonstrated on Madura beef cow.
Entrance Surface Dose (ESD) Measurement During Pediatric Chest X-Rays
Authors: Davoodi Roya , Eydian Mohammad Reza , Farokh Reza Rezazadeh- , Maraei Asma
Published: February 2021

Introduction
Given the high radiation tissue sensitivity of pediatric patients, it is necessary to monitor their received dose in order to optimize radiation protection. The first aim of this study was to evaluate of the entrance surface dose (ESD) in pediatric patients undergoing chest x-ray at the main hospital of Dezful, Iran. The second aim was to compare our results with the established dose reference levels (DRL).

Materials and Methods
The studied population included 204 pediatric patients less than 15 year who were referred to chest x-ray. A calibrated dose area product meter (DAP-meter) with permanent installation on x-ray unit was used to radiation dose measurements. For each patient, the demographic data, exposure parameters and the dose read by DAP-meter were recorded and ESD was calculated using standard mathematical formula.

Results
The average value of ESD was 119 μGy in patients less than 15 years. This value was 51.3, 122.3, 131.5 and 171.2 μGy for the age groups less than 1 year, 1 to 5 year, 5 to 10 year and 10 to 15 year, respectively. A statistical significant difference was seen between ESD values ​​in different age groups (P<0.001), whereas no statistical difference was seen between ESD values in ​ girls and boys (P =0.993).

Conclusion
Pediatric patients in hospital investigated (except age group less than 1 year) are subjected to unnecessary radiation exposure, especially due to use of non-optimize x-ray protocols.
Variation of Ethnomycological Knowledge in a Community from Central Mexico
Authors: Eribel Bello-Cervantes Eribel Bello-Cervantes , Metrio Alexander Correa- , Montoya Adriana , Trejo Irma , Blanco Joaquín Cifuentes
Published: February 2021

We analyze the effects of the ethnomycological knowledge depending on the age range of its users and how far their homes are from the forest areas. As a study model, the traditional mycological knowledge of San Pedro Tlalcuapan SPT, in Central Mexico was used. During 2017, 135 semi-structured interviews were conducted with people of three age ranges and living in three areas of the community located at different distances from the forest. Data was analyzed using descriptive statistics and analyses of non-metric multidimensional scaling, which were then applied to calculate two indices. The effect of age and origin of the individuals on bio-cultural relevance was assessed using multiple linear regression models.Fifty species of edible wild mushrooms were registered, those mentioned most often were of the Russuladelica complex., Amanita basii and Boletus aff. edulis. Ninety-five percent of the people interviewed consumed wild mushrooms on average two times a week, while 57% collected them. Wild mushrooms are mainly recognized for their food and ecological importance. Ordination and regression analyses show that people closest to the forest, as well as older people, are able to identify more of the wild mushrooms and have greater bio-cultural mushroom awareness. Results show that there is a risk that traditional knowledge about wild mushrooms will disappear, since it is only popular in a part of the community and only at some age ranges, indicating that there is a disconnect in the transfer of knowledge.
Influence of Carbon - Nitrogen Supplements and pH on Growth of Sugarcane Stem rot Pathogen Fusarium Solani NVS671
Authors: Patel Prittesh
Published: February 2021

Fusarium solani NVS671 identified from infected sugarcane stem of Co 671 as a new pathogen was subjected to various cultural conditions to understand its physiological profile. In continuation with our previous work, cultural analysis was carried out under in vitro condition by supplementing various carbon and nitrogen sources in Czapek-Dox agar (CDA). Under different hydrogen ion concentrations, it was found that the growth of Fusarium solaniNVS671 was less at pH 4 and pH 10 and could reach up to 5 cm after 7 days of incubation on Potato Dextrose Agar (PDA). It is observed that the pH around 7 to 8 was optimum for the growth of F. solani. Ten different nitrogenous (N) sources and nine different carbon sources were tested on CDA medium to know their effect on the mycelial growth rate and characteristics of the fungus. Among the N sources evaluated, ammonium chloride (7.96±0.11 cm) was found to be most efficient for mycelial growth promotion followed by ammonium nitrate (7.7±0.1 cm) and ammonium sulphate (7.3±0.1 cm). The most preferred carbon source recorded to promote best radial mycelial growth was starch (7.96±0.05 cm) and sucrose (7.93±0.05 cm). Capabilities of using different carbon and nitrogen sources and ability to grow at different pH levels may allow species to adapt to specific soil conditions.This study is important to understand the physiology and metabolite preference of F. solani.
Factors Enhancing Treatment of Hepatitis C Virus–Infected Italian People Who Use Drugs: The CLEO-GRECAS Experience
Authors: Rinaldi Luca , Messina Vincenzo , Di Marco Vito , Iovinella Vincenzo , Claar Ernesto , Cariti Giuseppe , Sacco Rodolfo , De Luca Massimo , Scifo Gaetano , Gatti Pietro , Barbarini Giorgio , Pace Palitti Valeria , Quartini Mariano , Tundo Paolo , D'Offizi Gianpiero , Parruti Giustino , di Rosolini Maria Antonietta , Garrucciu Giovanni , Cosco Lucio , Benanti Francesco , Gimignani Giancarlo , Vespasiani Gentilucci Umberto , Di Lorenzo Francesco , D'Antò Maria , Nevola Riccardo , Lupia Tommaso , Rosato Valerio , Morbiducci Valeria , Luzzitelli Ilaria , Sozio Federica , Di Stefano Marco , Ciraci Emanuela , Bulla Fabio , Guarisco Riccardo , Cangiano Cecilia , Imparato Michele , Maggi Paolo , Ascione Antonio , Craxì Antonio , Izzi Antonio
Published: February 2021

INTRODUCTION:

We assessed the performance of direct-acting antivirals (DAAs) in hepatitis C virus (HCV)-infected people who use drugs (PWUDs) in terms of sustained virological response (SVR) and adherence rates in comparison to a location-matched cohort of non-PWUD HCV patients.

METHODS:

All consecutive HCV RNA-positive PWUDs were enrolled between 2015 and 2019. All subjects underwent DAA treatment according to international guidelines and then followed, at least, up to 12 weeks after the end of treatment (SVR12). The SVR and adherence to treatment was compared with that of non-PWUD HCV patients observed at hepatological units of the CLEO platform. Intention-to-treat analysis was performed.

RESULTS:

A total of 1,786 PWUDs who were followed up were available for assessment. Most PWUDs (85.4%) were managed inside the specialized outpatient addiction clinics (SerDs). The overall SVR rate was 95.4%. The SerDs group achieved an SVR rate of 96.2% compared with 91.6% of the non-SerDs group (P < 0.001). Comparison with the non-SerDs group and the control HCV group showed a significant difference in the dropout rate (0.6% in the SerDs group versus 2.8% in the non-SerDs group and 1.2% in the control group; P < 0.001). At multivariate analysis, factors independently associated with SVR were use of the most recent regimens (elbasvir/grazoprevir, glecaprevir/pibrentasvir, and sofosbuvir/velpatasvir; odds ratio: 3.126; P = 0.000) and belonging to the SerDs group (odds ratio: 2.356; P = 0.002).

DISCUSSION:

The performance of DAAs in PWUD is excellent, if 2 conditions are met: (i) that the latest generation drugs are used and (ii) that the patients are managed within the SerDs.
Pengembangan Buku Panduan Outboundkids Kelompok Usia 5-6 Tahun
Authors: Sa’ul Afiyah Aulya Fitriyani , Purnama Sigit
Published: February 2021

Penelitian dan pengembangan ini dilakukan untuk (1) Mengetahui, pengembangan buku panduan outboundkids kelompok usia 5-6 tahu ndengan menggunakan model Borg dan Gall, (2) mengetahui kualitas buku panduan outbound kids berdasarkan penilaian ahli materi, ahli media, pendidik anak usia dini, dan instruktur outbound. Penelitian ini menggunakan model pengembangan Borg dan Gall dengan 10 langkah, tetapi peneliti hanya terbatas hingga 5 tahap, antaralain (1) Penelitian dan pengembangan data. (2) Perencanaan. (3) Pengembangan produk awal. (4) uji coba lapangan awal. (5) Revisi hasil uji lapangan awal. Hasil penelitian dan pengembangan menunjukan bahwa (1) Berdasarkan penilaian ahli materi, kualitas buku Sangat Baik (SB) dengan skor 51 dari 55 dan persentase keidealan 92.72%. (2) Menurut penilaian ahli media, kualitas buku Sangat Baik (SB) dengan skor 54 dari 55 dan persentase keidealan sebesar 98%. (3) Sedangkan menurut penilaian pendidik anak usia dini menunjukkan bahwa kualitas buku Sangat Baik (SB) dengan skor 101,7 dari 115 dan persentase keidealan sebesar 81.44% (4) Dan menurut instruktur outbound menunjukkan bahwa kualitas buku Baik (B) dengan skor 64.5 dari 80 dan persentase keidealan sebesar 76%.
Is Islam Compatible with Modernity? An Analysis of Modernity as Modern Civilization
Authors: Kamil Sukron
Published: February 2021

The relation between Islam and modernity as modern civilization is frequently faced contradiction. The disclaimer of a secular state for instance, leads to the debate by which the articulation of some Muslims who reject it is much more than those who accept it. Another example is humanism such as religious freedom and capitalism, although the disclaimers of these two issues are softer than those who denied the nation-state. However, the conceptual analysis points out that Islam is compatible with modernity as modern civilization. The main reason is that Islam was first emerged as a critic against the previous religion that was not engage the social transformation for the Arab society before Islam. Islam is also encouraged contemporary thought and social reform with the concept of ishlah (reform) and tajdid (renewal). If this case is measured based on the dimension of modernity, it obvious that Islam Islam as a teaching/conceptual frame/mindset in this article does not have conflict with it. Islam is in line with the nation state, secular country or secularism itself, democracy as political system, rationalism and empirical science, and capitalism. This paper is expected to strengthen the Integration of Islam as society with the modernity as modern civilization in the East and West countries.
PRAKTIK PENERAPAN EXCLUSIONARY RULES DI INDONESIA
Authors: Ilyas Adam
Published: February 2021

Alat bukti merupakan sebuah komponen penting dalam hal untuk memutuskan suatu perkara tindak pidana karena dengan alat bukti itulah yang akan menimbulkan keyakinan hakim atas kebenaran adanya suatu tindak pidana yang telah dilakukan oleh terdakwa. Karena pentingnya alat bukti sehingga penting pula adanya penerapan Exclusionary Rules. Dalam tulisan ini dibahas mengenai penerapan Exclusionary Rules, permasalahan dalam penerapan dan solusi atas permasalahan tersebut. Hasilnya, praktiknya di Indonesia belum secara mutlak menerapkan prinsip Exclusionary Rules ini karena permasalahan dari aturan dan penegak hukumnya, sehingga seringkali menimbulkan ketidakpastian hukum, ketidakadilan hukum, dan bahkan membentuk kultur korup penegakan hukum di Indonesia. Berdasarkan hal tersebut diperlukan adanya revisi terhadap Kitab Undang-Undang Hukum Acara Pidana terkait perkuatan penerapan prinsip Exclusionary Rules untuk memberikan perlindungan terhadap integritas pengadilan dan hak asasi manusia.
Kobayashi—Hitchin correspondence for twisted vector bundles
Authors: Perego Arvid
Published: February 2021

We prove the Kobayashi—Hitchin correspondence and the approximate Kobayashi—Hitchin correspondence for twisted holomorphic vector bundles on compact Kähler manifolds. More precisely, if X is a compact manifold and g is a Gauduchon metric on X, a twisted holomorphic vector bundle on X is g−polystable if and only if it is g−Hermite-Einstein, and if X is a compact Kähler manifold and g is a Kähler metric on X, then a twisted holomorphic vector bundle on X is g−semistable if and only if it is approximate g−Hermite-Einstein.
Developing Computational Thinking Skills Through Modeling in Language Lessons
Authors: Rottenhofer Marina , Sabitzer Barbara , Rankin Thomas
Published: February 2021

Technology is rapidly changing the world around us and thus, there is a need to adjust education by teaching children skills that are required in the fast-paced digital life. One problem-solving skillset, which has gained considerable attention in the last couple of years, is computational thinking (CT). Up to now, many countries have already implemented CT as an integral part of their education curricula, however, there is still often the misconception that teaching CT requires high technical effort and profound knowledge of computer science. Whereas CT is useful in any subject, it is not necessarily linked to technology and helps children to tackle problems by applying skills that are used in computer science. One effective hands-on approach to foster CT in every subject is modeling. A model is a simplified and reduced version of the real world and modeling is the process of creating it. In this paper, the authors focus on fostering CT skills with models from the field of computer science (CS) in foreign language teaching. The authors present several CS models, that have proven to be useful in language teaching, demonstrate how this approach can foster CT skills and give an insight into their research.
Effects of Cryogenic Treatment on the Microstructure and Mechanical Properties of High-alloyed Tool Steels
Authors: Schulz Alwin , Cui Chengsong , Steinbacher Matthias , Ümit Tuncer , Wunde Martin , Jung Ingrid , Acar Serdal , Nürnberger Florian , Gerstein Gregory , Herbst Sebastian , Maier Hans Jürgen
Published: February 2021

In this work, the influence of a cryogenic treatment on the microstructure, mechanical properties and wear resistance of the high-alloyed tool steels X38CrMoV5-3, X153CrMoV12 and ~X190CrVMo20-4 were investigated. Based on tempering curves of the steels, the heat treatment parameters were determined for the mechanical and wear specimens so that the conventionally heat-treated steels and the cryogenically treated steels featured similar hardness. The investigations showed that an almost complete transformation of retained austenite and a more homogeneous distribution of secondary carbides in the microstructure could be achieved by incorporating a cryogenic treatment. However, the cryogenic treatment does not show significantly positive effects on the investigated mechanical properties and wear resistance of the tool steels. The wear resistance of the samples was dominated by primary carbides. The cryogenic treatment would have a positive effect on large tool components with large wall thicknesses in terms of uniform and complete transformation of retained austenite throughout the entire components.
Traditional knowledge to clinical trials: a review on nutritional and therapeutic potential of Pithecellobium dulce
Authors: Dhanisha Suresh Sulekha , Drishya Sudarsanan , Guruvayoorappan Chandrasekharan
Published: February 2021

The review describes botanical aspects, bioactive phytocompounds and pharmacological properties of different parts of Pithecellobium dulce, with special emphasis on the nutritional status of its fruits. The different parts of plant extract have been reported to possess anti-oxidant, anti-inflammatory, anti-microbial, anti-diabetic, cardio protective, anti-diarrhoeal, anti-ulcerogenic, larvicidal and ovicidal activities. Different parts of plant extracts were reported to contain several bioactive phytocompounds such as flavonoids, saponins, tannins, alkaloids etc. Natural products discovered so far served as a viable source for new drugs. Over the past few years, continued and perpetual attention of people has been paid to medicinal plants in connection with its remarkable importance in drug discovery. Plant products always remains a drug of choice for the identification of novel leads despite facing a tough competition from existing synthetic alternatives derived from combinatorial chemistry, owing to their efficacy, side effects, and safety. P. dulce is a highly acclaimed genus in traditional system of medicine because of its versatile nutraceutical and pharmacological properties. In this review we discuss in detail about nutritional and various therapeutic properties of P. dulce.
Potential anti-toxic effect of d-ribose-l-cysteine supplement on the reproductive functions of male rats administered cyclophosphamide
Authors: Oludare Gabriel O. , Afolayan Gbenga O. , Semidara Ganbotei G.
Published: February 2021

Objectives

This study aimed to access the protective effects of d-ribose-l-cysteine (DRLC) on cyclophosphamide (CPA) induced gonadal toxicity in male rats.

Methods

Forty-eight male Sprague-Dawley rats were divided into six groups of eight rats each. Group I the control, received distilled water (10 ml/kg), Group II received a single dose of CPA 100 mg/kg body weight intraperitoneally (i.p), Groups III and IV received a single dose of CPA at 100 mg/kg (i.p) and then were treated with DRLC at 200 mg/kg bodyweight (b.w) and 400 mg/kg b.w for 10 days, respectively. Rats in Groups V and VI received DRLC at 200 and 400 mg/kg b.w for 10 days, respectively. DRLC was administered orally.

Results

Results showed that CPA increased percentage of abnormal sperm cells and reduced body weight, sperm count, sperm motility, follicle-stimulating hormone (FSH), luteinizing hormone (LH) and testosterone levels (p<0.05). CPA also induced oxidative stress as indicated by the increased malondialdehyde (MDA) content and reduced activities of the oxidative enzymes measured (p<0.05). Liver enzymes were elevated while the blood cells production was decreased in the rats administered CPA. DRLC supplementation enhanced the antioxidant defence system as indicated in the reduced MDA levels and increased activities of the antioxidant enzymes when compared with CPA (p<0.05). Bodyweight, sperm count, sperm motility, FSH, and testosterone levels were increased in the CPA + DRLC II group compared with CPA (p<0.05).

Conclusions

The results of this present study showed that DRLC has a potential protective effect on CPA-induced gonadotoxicity.
Suppress Me if You Can: Neurofeedback of the Readiness Potential
Authors: Schultze-Kraft Matthias , Jonany Vincent , Binns Thomas Samuel , Soch Joram , Blankertz Benjamin , Haynes John-Dylan
Published: February 2021

Voluntary movements are usually preceded by a slow, negative-going brain signal over motor areas, the so-called readiness potential (RP). To date, the exact nature and causal role of the RP in movement preparation have remained heavily debated. Although the RP is influenced by several motorical and cognitive factors, it has remained unclear whether people can learn to exert mental control over their RP, for example, by deliberately suppressing it. If people were able to initiate spontaneous movements without eliciting an RP, this would challenge the idea that the RP is a necessary stage of the causal chain leading up to a voluntary movement. We tested the ability of participants to control the magnitude of their RP in a neurofeedback experiment. Participants performed self-initiated movements, and after every movement, they were provided with immediate feedback about the magnitude of their RP. They were asked to find a strategy to perform voluntary movements such that the RPs were as small as possible. We found no evidence that participants were able to to willfully modulate or suppress their RPs while still eliciting voluntary movements. This suggests that the RP might be an involuntary component of voluntary action over which people cannot exert conscious control.
Neoliberalism and Authoritarianism: Martin Beddeleem in Conversation with Thomas Biebricher
Authors: Biebricher Thomas , Beddeleem Martin
Published: February 2021

Martin Beddeleem, member of the Global Perspectives Emerging Scholars Forum, talk about Thomas Biebricher’s book on the political theory of neoliberalism as well as Biebricher’s article in Global Perspectives, teasing out links between neoliberal thought and forms of authoritarianism.
Nazwa babka 'Plantago' i jej odpowiedniki słowiańskie
Authors: Falińska Barbara
Published: February 2021

Taking into consideration Ogólnosłowiański atlas językowy /Slavonic linguistic atlas/ as a basis for her analysis, the author presents geographical scopes, frequency and lexical, semantic and word-formation collocations of the etymologically Polish name for the plant babka, Latin plantago, in a descriptive and tabular approach set against a broad Slavonic background.
Ponencia - Darwin Arturo Muñoz Buitrago - Lima, Perú - 2014
Authors: Darwin Arturo Muñoz Buitrago
Published: February 2021

Informe de movilidad académica. Universidad de San Marcos, Lima, Perú.
Ponencia - Hugo Alejandro Sanchez Hernandez - Konstanz, Alemania y Madrid,España - 2015
Authors: Hugo Alejandro Sanchez Hernandez
Published: February 2021

Informe de movilidad académica.
‪Curso - Sandra Patricia Ramirez Montes - La Haya, Holanda - 2015
Authors: Sandra Patricia Ramirez Montes,
Published: February 2021

Informe de movilidad académica. Objetivo: Participar en la III Edición del Concurso de Simulación Judicial ante la Corte Penal Internacional y en la Semana Iberoamericana de la Justicia Internacional.
Ponencia - Claudia Lilian Londoño Castañeda - Madrid, España - 2015
Authors: Claudia Lilian Londoño Castañeda
Published: February 2021

Informe de movilidad académica. Universidad Complutense de Madrid.
Ponencia - Carlos Andrés Peña Guzmán - Alicante, España - 2015
Authors: Carlos Andrés Peña Guzmán‬
Published: February 2021

Informe de movilidad académica. Estancia investigativa y producción científica Universidad de Alicante, España.
La Lectura Y La Escritura Como Mediación Pedagógica Para La Formación Integral De Los Estudiantes
Authors: Clara Inés Jaramillo Gaviria , Edwin Francisco Forero García , Adriana Cecilia Páez Pino
Published: February 2021

En el presente artículo se pretende reflexionar sobre las posibles soluciones al problema que se nos plantea en la academia al tratar de promover en nuestros estudiantes una actitud comunicativa que les permita establecer diálogos que responda a las necesidades comunes al ser humano y al entorno en que vivimos.
To Excite, From the Traditional to the Bio-Pedagogy
Authors: Adriana Páez Pino , Clara Inés Jaramillo Gaviria , Edwin Francisco Forero García
Published: February 2021

Western societies are directly influenced by industrial and educational models developed and imposed by the West, are being confronted with themselves from their mother cell: the individual. Every day, the reality of an environment or a culture requires the human being other than raise his hand and his voice in order to explain and assert their difference, without guarantees to be heard, that is why the processes of formation of beings human, having lived boom of the specification and academic segmentation of knowledge, have also had to start a spin sheet themselves, taking angles and coherent strategies with individuals receiving their contents but not to apply them mechanically but precisely to articulate, dynamic setting meeting points that articulate the concepts and societies, enhancing the lifestyles of the inhabitants and users of every place on earth, with its different climates and soils, with their own abundance and wants to by stimulating and managing autopoietic learning education systems, whose maintenance involves reciprocity provided between the learner and their habitat.
Docencia - Jairo Enrique Ordóñez Garzón - Salito, Mexico - 2015
Authors: Jairo Enrique Ordóñez Garzón
Published: February 2021

Informe de movilidad academica. Objetivo: Dictar un curso sobre Análisis de Medios y presentar un libro del Semillero de Arte Callejero.
Ponenecia - ‪Fredy Leonardo Reyes Albarracin‬ - San salvador, El Salvador - 2015
Authors: Fredy Leonardo Reyes Albarracin‬
Published: February 2021

Informe de movilidad, Participación en el 55 Congreso Internacional de Americanistas.
Del capitalismo cognitivo a la biopedagogía “una propuesta por la vida”
Authors: Clara Inés Jaramillo Gaviria , Edwin Francisco Forero García
Published: February 2021

Las ideas de la ilustración cumplieron una doble función para consolidación de la mentalidad moderna. Por una parte, concibieron un ideal de hombre que diera repuesta a las exigencias propias del contexto: un hombre ilustrado capaz de pensar por sí mismo y capaz fraguar su destino a partir de la razón; un hombre trabajador capaz de transformar la naturaleza y de someterla en pro de su beneficio; un hombre concebido como persona, cuya valía y dignidad se fundamentan en sí mismo, capaz de participar en la sociedad política a partir de sus deberes y, sobre todo, de sus derechos; un hombre libre capaz de construir sociedades democráticas fraternas e igualitarias; un hombre capaz de educar y educarse según los logros de la cultura
Efectos de la gestión de la calidad en la prestación de los servicios del sector público en Colombia
Authors: Guillermo Peña Guarín
Published: February 2021

La calidad con que desarrollan sus actividades las entidades del sector público impacta en gran medida el funcionamiento de la economía del país e incide sobre la calidad de vida de los ciudadanos. Para mejorar la calidad de las entidades públicas, el gobierno colombiano ordenó en el año 2004 la implementación del sistema de gestión de la calidad en entidades del sector público, bajo la norma técnica NTCGP 1000, la cual está basada en el modelo internacional ISO 9001. Esta investigación se encamina a determinar los efectos que esta decisión ha tenido sobre la calidad de los servicios que prestan las entidades del sector público a los ciudadanos, vista desde dos perspectivas, la de los funcionarios que desde adentro de las entidades han vivido la implementación del sistema de gestión de la calidad y la de los usuarios que utilizan los servicios de las entidades públicas. A partir de los principios y requerimientos de la norma técnica NTCGP 1000 se establecen categorías y variables que posteriormente se llevan a encuestas, las cuales son aplicadas a muestras aleatorias de servidores públicos y de usuarios. Una vez procesados los datos se identifican las capacidades que el sistema de gestión de la calidad ha logrado desarrollar en las entidades y los efectos que ha tenido sobre la calidad de los servicios que brindan las entidades públicas.
Ponenecia - ‪Oscar Rodrigo Lopez Vaca - Amsterdam, Holanda - 2014
Authors: Oscar Rodrigo Lopez Vaca
Published: February 2021

Informe de movilidad académica, Amsterdam, Holanda, 12th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering CMBBE2014
Ponencia - Fernando Guío Gutiérrez - La Paz, Bolivia - 2015
Authors: Fernando Guío Gutiérrez
Published: February 2021

Informe de movilidad académica, Presentación ponencia y conferencia taller, Ministerio de Deportes de Bolivia.
Ponenecia - ‪Yennys González de los Reyes‬ - Madrid, España - 2015
Authors: Yennys González de los Reyes
Published: February 2021

Informe de movilidad académica. III Congreso Internacional de actividad Física y Deporte
Tindak Pidana Penipuan dan Pencucian Uang Yang Dilakukan Oleh PT. First Anugerah Karya Wisata (Studi Kasus : Putusan Nomor : 3096 K/Pid.Sus/2018)
Authors: Mawarni Iga Ayu , Asmawi Asmawi , Siradj Mustolih
Published: February 2021

Penelitian ini bertujuan untuk menganalisa perampasan asset untuk negara dari PT First Anugerah Karya Wisata sudah sesuai dengan asas keadilan dan ketentuan hukum yang berlaku dan juga menjelaskan pertimbangan hukum hakim dalam menjatuhkan putusan serta mendeskripsikan hakim dalam menginterpretasikan pasal-pasal yang digunakan. Dari segi jenis penelitian hukum, jenis Tipe penelitian yang digunakan dalam  penelitian ini adalah yuridis normatif,  yaitu pendekatan  yang mengacu kepada norma-norma hukum yang terdapat dalam peraturan perundang-undangan dan putusan-putusan  pengadilan serta norma-norma hukum yang terdapat  dalam masyarakat. Hasil dari penelitian ini menunjukkan bahwa apabila dilihat dari sisi korban tidak terpenuhinya rasa keadilan dalam putusan ini tidak juga ada kemanfaatan hukum yang terkandung dalam putusan ini. Mengingat sampai pada tingkat Kasasi, Hakim tetap menyatakan aset dirampas untuk negara yang sejatinya tidak ada sedikitpun kerugian negara yang dialami. Kata Kunci: Tindak Pidana, Penipuan, Pencucian Uang, Perampasan Aset.