bluuebunny/crossref_metadata_2025 huggingface dataset:
Mevlânâ’nın Hürriyet Kavramına Yaklaşımı
Authors: ERTEN Murat
Published: December 2022

İnsanın eylemlerinin değerini belirleyen iki özellik, sağlıklı bir düşünme kapasitesi, böyle eylemeyi sağlayacak bir kararlılık ve irade gücüne sahip olmaktır. Kısaca düşünebilmek ve yapabilmektir. Hürriyet, insanın iyiyi bilinçli bir şekilde seçmesi ve iradî biçimde iyi eylemesidir. Böyle eyleyen kimsenin sağlıklı bir zihin yapısına sahip olduğu ve iradesini aklının öngördüğü biçimde kullandığı anlaşılır. Buna karşın kötü eylem hem bireysel hem toplumsal anlamda ya reddedilen ya da cezalandırılan eylemdir. Çünkü kötü eylemlerden dolayı ortaya olumsuz sonuçların çıkması ve bunların sorumluluğunun alınması kaçınılmazdır. Bu durumda, kötü olanı seçen kimsenin sağlıklı düşünemediği, akılsal gerekçelerden hareket etmediği ve eylemlerinin sonuçlarını önceden kestiremediği anlaşılır. O halde kötü olanı seçmek kişiyi hür kılmak bir yana hürriyetten uzaklaştırır veya tümden yoksun bırakır. Bu anlamda hürriyet negatif bir anlama sahip olamaz veya negatif bir eylem özgürlüğünden söz edilemez. Mevlânâ’nın hürriyet kavramına ilişkin görüşlerini ilahî-insanî irade, irade hürriyeti ve bu kavramlar arasındaki ilişki bağlamında ele almak mümkündür. İnsan, irade eden bir varlıktır. Mevlânâ dilediğini yapma gücüne sahip olmak ile seçim yapmak kavramlarını aynı anlamda kullanır. Böylece hür irade ve seçme hürriyetine sahip insan iyi, doğru ve güzel olanı seçtiğinde nasıl övgü ve beğeniye mazhar olursa, kötü, yanlış ve çirkin olanı seçtiğinde de sonuçlarına katlanmayı ve sorumluluğu almayı bilmelidir. Ona göre irade hürriyetinin önünde engel olarak görülen kader kavramı ile seçerek eyleme hürriyeti ve bilinçli tercih arasında girift bir ilişki bulunur. Bilinç sahibi insan, hür iradesi ile hareket etme imkânına, seçme hak ve özgürlüğüne sahiptir, bundan dolayı yapıp ettiklerinden sorumlu tutulur. Bununla birlikte insanın fiillerinin ve tercihlerinin dayanağını teşkil eden sebeplerin ezelde yaratıcısı Tanrıdır.
Hypertension Risk Factors in Batu Ampar Public Health Center West Borneo
Authors: Devara Karunia Esa Putu
Published: December 2022

Many people do not know that they have been diagnosed with hypertension until complications arise. Hypertension is a non-communicable disease caused by many factors. The risk factors that influence the incidence of hypertension are divided into two: modifiable and non-modifiable risk factors. Thus far, there is no data on risk factors for hypertension in the Batu Ampar Public Health Center work area. The objective of research is knowing the risk factors for hypertension in the working area of Batu Ampar Public Health Center. An observational study with a cross sectional design conducted at the Batu Ampar Public Health Center from April to June 2022. The variable data collected were age, gender, education level, occupation, obesity, smoking habits, exercise habits, alcohol consumption, salt consumption and fruit consumption. and vegetables. Of the 150 respondents (75 with hypertension and 75 without hypertension) it was found that age, occupation, alcohol consumption and salt consumption were risk factors. The probability of hypertension having these four risk factors is 97%. Risk factors for hypertension in the working area of Batu Ampar Public Health Center are age, occupation, alcohol consumption and salt consumption.
Correlation between Adequacy of Fe Tablet Consumption, Nutritional Status and Diet with Anemia in Pregnant Women at BPM Hj. Carnah N, S.ST Karawang in 2021
Authors: Sinta Sinta , Kuswati Kuswati
Published: December 2022

Anemia is a medical condition in which the number of red blood cells or hemoglobin is less than normal. Anemia in pregnant women is a condition in which hemoglobin levels in the blood are lower than the normal value for hemoglobin levels below 11 g% in the first and third trimesters or <10.5 g% in the second trimester. The purpose of this study was to determine the relationship between adequate consumption of Fe Tablet, nutritional status and diet with anemia in pregnant women at BPM Hj. Carnah N, S.ST Karawang in 2021. This research is a descriptive analytic study with a cross-sectional approach, the sample in this study was taken using a total sampling of 55 people. How to collect data by distributing questionnaires. The results of the Chi-square statistical test for the adequacy of FeTablet consumption (P-value = 0.002) with OR 7333, nutritional status (P-value = 0.005) with OR 5937, and diet (P value = 0.007) with OR 5.714 . The conclusion is that there is a relationship between the adequacy of Fe Tablet consumption and anemia in pregnant women at BPM Hj. Carnah N, S.ST Karawang in 2021. This research resulted in an achievement where a tool in the form of a leaflet was made to make it easier to educate by making it as attractive as possible.
Care Management of Premarital Women Using Clear Counseling Techniques, Roles Body Attitudes and Gather Approaches
Authors: Hendayani Siti Nur Endah , Rosyeni Yeni , Setiowati Tri
Published: December 2022

Prevalence of child marriage in Indonesia has more than doubled in recent years but is still one of the highest in the East Asia and Pacific region crease of mother knowledge through education. This of course has an indirect impact on increasing high risk, both morbidity and mortality for mothers and babies to be born. Reproductive health of the bride and groom is a very important thing in order to prepare mothers to be the creators of a healthy and quality generation. The aims of this  study is to conduct counseling management for premarital women with the CLEAR counseling technique, ROLES body attitude and the GATHER approach. This study uses a  case study design with a descriptive observational method with a focus on the application of CLEAR, ROLES and GATHER counseling techniques. The subject of this case study is Ms. M, aged 24 years. This case study was carried out at PMB Siti Nuraeni in May 2022. Data was collected directly (primary data) using the Varney management approach and documentation in the form of SOAP (subjective data assessment, objective data assessment, data analysis and case management). Then the data were analyzed in descriptive analysis. Conclusion of this study that counseling technique used in premarital care cases is in accordance with the theory, namely by using the CLEAR technique (Clarifying, Listening, Encouraging, Asking for feedback, Repeating). Body posture uses the ROLES approach (Relaxing, Opening up the client, Learning toward the client, Establishing eye contact, Smiling and squarely). Implementation of counseling steps in premarital care cases is carried out according to the "GATHER" approach (Greet, Ask, Tell, Help, Explain, and Return).
A “Solitary” Narrative in Context of Cultural and Spatial Identity: Kayaköy
Authors: YAMAK Gürol , BİÇER Ürün
Published: December 2022

Anatolian geography has hosted many civilizations which have been able to carry their beliefs, languages, customs and traditions, lifestyles and traces as original pieces in the multicultural mosaic of Anatolia. These "ancient" values, which have been transferred to the present day as cultural heritage, constitute the life codes of the societies that make them up. On the other hand, as the smallest part of society, man, who had to leave the space that he had created, shaped and kept alive with his own hands in one way or another from ancient times to the present, followed the traces of the society to which he most belonged, searched for its essence and questioned his "belonging". In this context, while the study seeks to find the spatial identity infrastructure, which includes the life codes of the Anatolian geography, in the social lives of societies, also aims to question the problem of belonging in context of the “forced migration” which is one of the most dramatic events in history that displaces societies in the process of nationization and detaches people from their "space”, to be able to read the place through the cultural accumulation and transfer of “exchanged lives”, to find the “lost” in the dimension of culture-space-time. There is no doubt that Kayaköy, which was chosen as the study area for this purpose deserves this attention with its experience of the forced migration in all its reality and nakedness, history, culture, unique architectural style and texture, locality, "sustainability" of the local, testimony of the period in question, abandonment and finally the “accounts” made on it by powers from different segments.
Pencegahan Kejahatan Ujaran Kebencian di Indonesia
Authors: G. Ambar Wulan Roberto G. M. Pasaribu; Mulyadi;
Published: December 2022

Abstract
The development of technology is not only in the form of having a positive impact in Indonesia, but also has a negative impact, namely the emergence of various types of violations and even a crime, namely the Hate Speech. Hate Speech (Hate Speech) Crimes are regulated in Act Number 11 of 2008 concerning Electronic Information and Transactions. This research uses a qualitative-descriptive approach. Research results Prevention of hate speech (Hate Speech) crime prevention efforts in Indonesia can be done in a way, Prevent hate speech crime acts by providing counseling or outreach to the general public regarding information on the impact of electronic media if not used wisely, ethics using media social by providing legal knowledge about the ITE Law.

Keywords: Prevention, Hate Speech, Hate Crimes

Abstrak
Perkembangan teknologi tidak hanya berupa memberikan dampak positif di Indonesia, namun juga memberikan dampak negatif yaitu munculnya berbagai jenis pelanggaran dan bahkan suatu kejahatan yaitu Ujaran Kebencian (Hate Speech). Kejahatan Ujaran Kebencian (Hate Speech) diatur dalam Undang-Undang Nomor 11 Tahun 2008 tentang Informasi dan Transaksi Eleketronik. Penelitian ini menggunakan pendekatan kualitatif-deskriptif . Hasil penelitian Upaya pencegahan kejahatan Ujaran Kebencian (Hate Speech) di Indonesia dapat dilakukan dengan cara, Upaya pencegahan terjadinya kejahtan ujaran kebencian (hate speech) dengan memberikan penyuluhan ataupun sosialisasi kepada masyarakat luas mengenai informasi dampak media elektronik jika tidak digunakan dengan bijak, etika menggunakan media sosial dengan memberikan pengetahuan hukum mengenai UU ITE.

Kata Kunci : Pencegahan, Ujaran Kebencian, Kejahatan Kebencian
Studies of the Effect of Hypnoanasthesia in Reducing Perineal Laceration Suture Pain And Healing of Postpartum Perineal Wounds in Indonesia
Authors: Mustika Ningrum Nining , Meinawati Lusianah , Sulistyawati Henny , Ismath Mohammed
Published: December 2022

Pervaginal childbirth until now is still the choice of the method of childbirth that is considered the safest and economical. Although the delivery assistance has been done correctly, most women will experience perineal trauma during the vaginal labor process and require perineal suturing. The problem that is often faced by a mother who has a perineal tear is pain during the suturing process and will last until the suture wound is dry and the duration of the healing process of the perineal suture wound. This type of research is quantitative analytics using a Quasi-Experimental research design with the one-group post-test design method. Free variables: Hypnoanasthetic method and bound variables: the pain of perineal suture wounds and healing of perineal wounds. The sample in this study was 66 maternity mothers using purposive sampling techniques. Instruments: Checklists and Observation sheets, data analysis using the Wilcoxon Test. The results showed that after being given the hypnoanastesi method, almost all respondents experienced mild pain during suturing perineal lacerations, namely 87.9% and most respondents took a fast time (2 weeks) in healing perineal wounds, namely 23 respondents (69.7%). This study concludes that the hypnoanastesi method is effective in reducing the pain of suturing perineal lacerations and is effective in the healing process of perineal wounds.
PEAK EXPIRATORY FLOW RATE (PEFR) VALUES OBTAINED WITH WRIGHT'S PEAK FLOW METER AND DIGITAL SPIROMETER IN OBSTRUCTIVE AIRWAY DISEASE (OAD) PATIENTS – A COMPARATIVE STUDY
Authors: Aparna Varikuti , Kissinger Kola Vijaya , Aruna Gorthi , Ramana Murthy Beenaboina. V.
Published: December 2022

Introduction: Peak expiratory ow rate (PEFR) is the highest ow achieved from a maximum forced
expiratory maneuver and is a good modality in diagnosing and monitoring Br.asthma; in COPD it gives a
rough estimate of the severity of obstruction.Normal values in males and females range between 320-550L/min. PEFR values
can be obtained by a Peak Flow Meter or by standard Spirometer. To compare PEFR values obtained Aims And Objectives: by
Wright's Peak Flow meter and those obtained by a Digital Spirometer and to understand Whether PEFR values are reliable in the
diagnosis and monitoring of Obstructive Airway Disease. 75 Consecutive patients who pr Materials And Methods: esented with
a history of COPD, Br.asthma or Bronchiectasis to the Respiratory Medicine OP, Govt General Hospital, Nellore, AP were
recruited to the studyand PEFR values were recorded by both Peakowmeter and Spirometer. The rang Results: e of PEFR values
obtained was between 120-480 L/min .and the difference was in the range of 9-164 L/min. In the present study the Conclusion:
difference in values is not very signicant andhence PEFR can be used as a diagnostic & monitoring tool in OAD.
A PRE-EXPERIMENTAL STUDY TO ASSESS THE EFFECTIVENESS OF SELFINSTRUCTIONAL MODULE ON KNOWLEDGE AND ATTITUDE REGARDING PREVENTION OF CORONARY ARTERY DISEASE AMONG TYPE 2 DIABETIC PATIENTS IN SELECTED HOSPITALS AT BENGALURU
Authors: Salah Falak , S Ramesh
Published: December 2022

Diabetes mellitus is a chronic, metabolic disease characterized by elevated levels of blood glucose,
which leads over time to serious damage to the heart, blood vessels, eyes, kidneys and nerves. The most
common is type 2 diabetes, usually in adults, which occurs when the body becomes resistant to insulin or doesn't make enough
insulin. The aim of the study was to assess the effectiveness of Self-Instructional Module on knowledge and attitude regarding
prevention of Coronary artery disease (CAD) among type 2 diabetic patients. A pre-experimental one group pre-post test study
design was adopted and convenience sampling technique was used to select 60 diabetic patients from selected hospitals. Their
pre and post test knowledge was assessed by self-administrated questionnaire and 5 points Likert sale was used to assess the
attitude. The results revealed that the mean posttest (23.5) was more than mean pre-test (17.52) for knowledge and attitude. The
value of paired t-test was (14.616) and it was found signicant at p<0.05 level. The study concluded that the Self –instructional
module (SIM) was signicantly effective in improving the level of attitude.
SIMPLE AND EFFECTIVE METHOD FOR MANAGEMENT OF FRACTURES OF BASE OF 1ST METACARPAL USING LIGAMENTOTAXIS AND MINI EXTERNAL FIXATOR FRAME
Authors: Belapurkar Kaustubh , Tathe Pankaj , Banik Soham
Published: December 2022

Background- Fractures of the base of rst metacarpal include intra-articular fractures like Rolando
fracture and Benette fracture. The ideal management modality of these fractures remains elusive.
Management varies from conservative therapy, k wire xations, external xators to formal open reduction and plate xation.
Open reduction and anatomic xation though lucrative, is frought with complications like stiffness, implant failure etc due to
excessive dissection and soft tissue stripping that is required. Conservative therapy is usually insufcient to allow the fracture
to heal in appropriate position as there are numerous muscle forces acting at the base of rst metacarpal which make
maintaining the reduction difcult. K wires allow to keep the fracture reduced but obtaining reduction is not an easy task. Here
we describe a minimally invasive technique using mini external xator-JESS(Joshi external stabilization system) which
requires minimum soft tissue dissection In this prospective study a total of 8 pati Results- ents were included who underwent
fracture xation using mini external xator frame. The average time to union was 4 weeks. None of the patients had iatrogenic
injury to supercial branch of radial nerve. All of the patients had excellent post xator frame removal hand function. MethodsA prospective analysis was carried out over 8 months. A total of 8 patients met the inclusion criteria and were operated with mini
external xator. Regular follow up was done till 8 weeks. At each postoperative visit patients were evaluated for hand function
using Kapandji Score Radiographs were taken at each visit to evaluate for fracture alignment and union. Mini Conclusionexternal xator is a simple, minimally invasive surgical technique with excellent functional outcomes for management of
Fractures of rst metacarpal
A STUDY ON, TREATMENT OF PROXIMAL HUMERUS FRACTURES USING PHILOS PLATE IN A TERTIARY CARE HOSPITAL.
Authors: F Akki Sandesh , C N Manjappa , Kumar K L Mahendra , Kumar H S Ravi
Published: December 2022

Fractures of proximal humerus is still unsolved fractures in many ways.A wide variety of treatment
modalities have been used for these fractures.The Proximal humeral internal locking system (PHILOS)
plate xation provides greater angular stability than do conventional implants.The aim of the study is to assess the functional
outcome of proximal humerus fractures treated with PHILOS plating.To recognize any associated complications.This was a
prospective study conducted fron August 2020 to February 2021 in our hospital with 5-6 month follow up. We include skeletally
matured patients with proximal humerus fractures with displacement >1cm and varus angulation of >45*.The outcome was
assessed using Neer's scoring system and recorded before treatment and on follow up at 1st month, 2nd month, 4th month and
6th month. Fracture healing assessed by consecutive radiographs.As per Neer's classication system, there were (11.32%)1
part, (35.85%)2 part, (32.08%)3 part and (20.75%)4 part fractures. Average surgical duration was 90+\- 15min. Radiological
union was seen at 12+\- 4 weeks.Among all the cases 13.2%cases had excellent results,69.8% had satisfactory results and
11.3% had unsatisfactory results.PHILOS plating has a good functional outcome for proximal humerus fractures in skeletally
matured patients.
ASSESSMENT OF THE OCCURRENCE OF MIDDLE MESIAL CANAL IN MANDIBULAR MOLARS USING CONE-BEAM COMPUTED TOMOGRAPHY AND DENTAL OPERATING MICROSCOPE: AN IN VITRO STUDY
Authors: Kar Suman , Bera Swarupananda , Maity A. B. , Paramita Pal Progyna , Das Gargi , Singh Anjali
Published: December 2022

Introduction: Failures of root canal treatments may be resulted due to missed canals and ignorance of
the clinician about the complex anatomy of the root canal system. One such example of anatomic
variation is the middle mesial (MM) canal in mandibular molars. Literature on methods for identifying them is limited. Aim: This
in vitro study aimed to assess the occurrence of MM canal with cone-beam computed tomography (CBCT) and then under
dental operating microscope (DOM) in the mandibular rst and second molars. A total of 40 extract Materials and Method: ed
intact human permanent mandibular rst and second molars were selected. These were subjected to CBCT imaging and
magnication under DOM for the detection of MM canals. The percentage of incidence in the detection of MMC was compared
between these two methods. The incidence of MM canals detected in mandibular molars using CBCT and Results: DOM was
7.50 and 10 % respectively and the comparison between the two methods was statistically not signicant. Since Conclusions:
the incidence of MM canals was higher with the use of DOM, it is preferred to use simpler, chairside aids like magnication and
ultrasonic troughing. On the other hand, one should be judicious in preoperative CBCT evaluation in nding accessory canals
like MM.
SENSORINEURAL HEARING LOSS IN ISCHEMIC STROKE - A LONGITUDINAL OBSERVATIONAL STUDY IN A TERTIARY CARE HOSPITAL.
Authors: D Ravi , N.K Balaji , M Haseeb , T.R Sowmya
Published: December 2022

Hearing impairment commonly involves dysfunction of the inner ear or auditory nerve, a condition known
as sensorineural Hearing loss (SNHL). A longitudinal observational study of 38 stroke patients was
conducted at a tertiary care hospital for a period of 6 months to know the proportion of sensorineural hearing loss in stroke
patients and also the progression of hearing loss during the recovery period of stroke. Clinical & audiological evaluation was
done for all patients and they underwent pure tone audiometry at serial intervals of 1st, 2nd and 3rd month from the date of
diagnosis of stroke. The proportion of sensorineural hearing loss in stroke patients was found to be 60%. On comparison of serial
pure tone audiometry readings, it was observed that hearing loss improved signicantly during the recovery period of stroke.
This study concluded that high proportion of sensorineural hearing loss in stroke patients indicates the importance of screening
for hearing loss to improve the rehabilitation as well as quality of life post stroke.
“CLINICAL EVALUATION OF THE EFFECT OF A NOVEL LACTOFERRIN CONTAINING TOOTHPASTE AS AN ADJUNCT TO SCALING AND ROOT PLANING IN IMPROVING PLAQUE CONTROL AND GINGIVAL HEALTHA RANDOMIZED CONTROLLED CLINICAL TRIAL”.
Authors: Indurkar Maya Sanjiv , Krishna. J Swathy
Published: December 2022

Aims and objectives: To evaluate the effect of a DENTE91® (novel lactoferrin based toothpaste) in comparison to
Standard fluoride based toothpaste as an adjunct to scaling and root Planing in improving plaque control and gingival
health. This was an examiner-blinded, parallel group, randomized, controlled trial enrolled total 10 Methodology: 0
healthy subjects aged 18 to 35 years (both inclusive) who had dental biofilm induced gingivitis, with at least 20 natural
teeth, who exhibited no evidence of clinical attachment loss and was ready to give written informed consent were
enrolled. Mean ± SD plaque Index score with Turesky–Gilmore–Glickman modification of Quingley Hein Results:
plaque index (S) was statistically significant within Test group (1.44 ± 0.40) and Control group (1.79 ± 0.36) as compared
to baseline (2.48 ± 0.43 in Test group and 2.72 ± 0.33 in Control group). Mean % ± SD reduction in plaque index score at
Week 4 was 42.04% ± 11.04% in Test group and 34.19% ± 14.21% in Control group as compared to baseline. Reduction in
plaque index was comparable between Dente 91® (Test group) and Standard fluoride based toothpaste. Mean ± SD
gingival Index score based on Loe and Silness, 1963 method was statistically significant at Week 4 (0.76 ± 0.38 in Test
group and 1.34 ± 0.56 in Control group) when compared to baseline (22.70 ± 0.67 in Test group and 2.65 ± 0.52 in Control
group). Mean % ± SD reduction in gingival Index score at Week 4 was 71.29% ± 12.96% in Test group and 48.54% ±
21.94% in Control group as compared to baseline. Reduction in Gingival Index score was statistical significant (p=0.001)
in Dente 91® (Test group) compared to Standard fluoride based toothpaste (Control group). The main Conclusion:
finding was that Test group who had used DENTE91® toothpaste containing lactoferrin had significantly better gingival
health status than the Control group in terms of gingival inflammation and gingival bleeding. Significant reduction in
plaque index score was comparable between Test group and Control group.
SEROPREVALANCE OF TRANSFUSION TRANSMITTED INFECTIONS AMONGST BLOOD DONORS IN TERTIARY CARE HOSPITAL IN U.P
Authors: Mudgal Saurabh , Goel Seema , Varshney Krati , Najmuddin Khan Mohammad
Published: December 2022

Background: The evaluation of the data of the prevalence of transfusion transmissible infections (TTI) among blood
donors permits an assessment of the acquisition of the infections in the blood donor population and consequently safety
of the collected donations. It gives an idea for the epidemiology of these infections in the population. Objectives: To
study seroprevalence of HIV,HBV,HCV,Syphilis and malaria in blood donors. Methods:Total of 4529 units of blood were
collected from voluntary and replacement donors during three years study period from Jan 2019 to dec 2021. All the
blood samples were screened for HIV,HbsAg,HCV,Syphilis and malarial parasites. Results: Out of the total 4529 blood
donors, replacement donors were (79.50%) more compared to voluntary donors (20.40%).The overall seroprevalence
of TTI was 4.10%.The seroprevalence of HIV,HbsAg and HCV was 0.04%,1.81% and 2.16% in total donors respectively.
No voluntary donor was found to be positive for HIV. The prevalence for HbsAg and HCV was more in replacement
donors 1.67% and 2.03% respectively as compared to voluntary donors 0.14% and 0.13% respectively.No donors were
found positive for Syphilis and Malaria. Conclusion: Replacement donors were found to be more seropositive for TTI as
compared to voluntary donors.Hence,more attention should be given for motivation of voluntary donors
BACTERIAL PROFILE OF BLOOD CULTURE AND THEIR ANTI-MICROBIAL SUSCEPTIBILITY PATTERN IN PEDIATRIC PATIENTS OF A TERTIARY CARE HOSPITAL
Authors: Saini Monika , Sharma Rajni , Sharma Shanoo , Mathur Sakshi
Published: December 2022

Introduction: Blood stream infection are very common in the pediatric age group and these are one of the common
causes of morbidity and mortality in children.In developing countries ,the rate of blood stream infection in children is
about 20-50%.The present study was undertaken to determine the etiological agents causing blood stream infection and
their antibiotic susceptibility pattern in pediatric patients. Patients with bacteremia may have either a transient
bacteremia or persistent bacteremia which can be self-limited without development of focal infection or sequelae or
may progress to a more serious fatal infection or toxic effects. Methodology: The present study in a hospital based
single centred, Observational study, of 3 years. Blood sample were collected in BacTec bottle and standard
microbiological protocol were applied for the isolation identification of bacteria strains.Antimicrobial susceptibility test
was performed by the Kirby Bauer Disc Diffusion Method as per CLSI 2019 guidelines. Results: Out of total 350 blood
samples received for culture,87(23.14%)were culture positive, out of which 42/87(48.27%) were Gram positive
organisms and 39/87(44.82%) were Gram-negative organisms and 6 /87(6.89%) were candida spp. The most common
organism was Staphylococcus aureus(31.03%) the predominant organism followed by Klebsiella
pneumoniae(21.83%) and Streptococcus pneumoniae (9.19%),Escherichia coli,Enterobacter cloacae each (5.74%).
All Gram positive bacteria were susceptibile to vancomycin, teicoplanin and linezolid. 11/27(40.74% )of
Staphylococcus aureus were Methicillin resistant Staphylococcus aureus (MRSA) strains. All Gram negative bacteria
were susceptibility to amikacin, Colistin,Tigecycline. Conclusion: Staphylococcus aureus is the leading cause of
childhood septicemia in this locale, has been decline in susceptibility of the pathogens to common antibiotics which
ultimately stresses on the need for continuous screening and surveillance for antibiotic resistance in the pediatric ward
and calls for increased efforts to ensure more rational use of these drugs.
NONCARDIOGENIC PULMONARY EDEMA AS SEQUEL OF VENOUS AIR EMBOLISM IN A CASE OF OPERATIVE HYSTEROSCOPY – A CASE REPORT.
Authors: Sultania Nidhi , Jain Vinita
Published: December 2022

Hysteroscopy is minimally invasive procedure performed widely for diagnosis and treatment of intrauterine and
endocervical pathologies.Venous air embolism,though rare complication,is catastrophic if encountered.We report one
such case of venous air embolism leading to non-cardiogenic pulmonary edema encountered by us during
hysteroscopic uterine septum resection done for infertility under general anaesthesia.Quick identification,preventing
further gas entry and timely intervention saved our patient.
Cistoadenoma mucinoso del apéndice cecal. Informe de caso
Authors: Orellana-Maldonado Dalia , Chan Cinthya
Published: December 2022

El cistoadenoma mucinoso del apéndice cecal es una de las 4 causas del mucocele, es muy poco frecuente, ocurre en el 0.2-0.3% de todas las apendicetomías. Presentamos el caso de una paciente femenina de 44 años de edad, en quien se encuentra tumor apendicular. El informe histopatológico reporta cistoadenoma mucinoso del apéndice.
Síndrome de Asherman: imagen en histerosalpingografía
Authors: Fajardo-Sandoval Miguel
Published: December 2022

El síndrome de Asherman incluye un conjunto de manifestaciones clínicas adquiridas, entre las más frecuentes están la infertilidad y los abortos, se caracteriza por formación de sinequias uterinas, posterior a un legrado. A continuación, se presenta el caso de una paciente de 23 años con antecedente de abortos a repetición, quien en  histerosalpingografía muestra sinequias uterinas, confirmadas con histeroscopia.
Presentación clínica atípica de intususcepción intestinal en un paciente lactante
Authors: Barrón-Balderas Alejandro , Chávez Vázquez Ana , Ortiz-Arriaga Alejandro , Solano-González Karla
Published: December 2022

La intususcepción intestinal es una emergencia abdominal común en pediatría, sobre todo en niños menores de dos años. La presentación clínica clásica consiste en la triada: dolor abdominal, tumoración abdominal y evacuaciones de grosella. Presentamos el caso de un menor de 7 meses de edad, cuyas manifestaciones clínicas fueron vómitos e irritabilidad. En el transoperatorio se reportó una invaginación intestinal de 15cm; la presentación clínica atípica de intususcepción debe ser considerada en aquellos lactantes con datos de letargo, alteración de la conciencia y datos clínicos gastrointestinales
Abordaje quirúrgico de un queratoacantoma gigante
Authors: Letona Nimzy , Herrera Fernanda , Toledo Adriana
Published: December 2022

Se presenta el caso de un paciente masculino de 66 años de edad, quien consultó por una lesión exofítica en la cara anterior del tórax de 6 meses de evolución. Mediante la correlación clínico-patológica se llegó al diagnóstico de queratoacantoma (carcinoma de células escamosas bien diferenciado). Se realizó una resección completa de la lesión. Para el cierre se utilizó la técnica del colgajo en Z.
Hemorragia pulmonar en caso de coccidioidomicosis con presentación inusual
Authors: Gramajo Marisol , Morales Kimberly , Aqueche Gabriela , Rodríguez-Monzón Astrid
Published: December 2022

C. immitis y C. posadasii conforman el género Coccidioides. Las presentaciones clínicas más comunes de la afectación pulmonar son fiebre, dolor de cabeza, tos, fatiga y dolor pleurítico. Las características histopatológicas descritas en la literatura son inflamación granulomatosa necrotizante, cavitaciones y presencia de micetomas, junto con la visualización de esférulas y/o hifas. Presentamos el caso de una mujer de 45 años de edad con manifestación clinica inusual de coccidioidomicosis.
Distribución de la respuesta a aeroalergenos en pacientes pediátricos alérgicos, utilizando el prick test
Authors: Álvarez–De-León Brandon , Escobar-Pérez Kenneth
Published: December 2022

Objetivo: conocer la distribución de la respuesta a aeroalergenos respiratorios en pacientes pediátricos con alergia. Material y métodos: estudio descriptivo del tipo serie de casos. Se incluyeron catorce pacientes con diagnóstico de asma alérgico que asistieron a la consulta externa de pediatría de nuestro centro, de enero 2019 a diciembre 2020. Resultados: la edad promedio de los pacientes fue de 8 ± 3 años, 71% de sexo masculino, la mayoría procedentes de Quetzaltenango (71%), contaban con casa propia (79%), construida con ladrillo y 86% poseían servicios básicos). En un 86% los biomarcadores alérgicos recolectados fueron eosinófilos periféricos en sangre 335 ± 179 células/mm3, IgE total fue de 804 ± 780 IU/L y vitamina D 32 ± 9 ng/dL. Los dos aeroalergenos que predominaron fueron ácaro  Dermatophagoides farinae y pelo de gato 64%, seguido de Alternaria alternata, pelo de perro y pelo de ratón 57%. Conclusión: las herramientas adecuadas como los biomarcadores de alergia y el prick test deben de ser parte de la evaluación inicial  pacientes con alergia respiratoria. Las estrategias de evitación medio ambiental, donde el prick test, tiene un papel preponderante puede ayudar a orientar a médicos, padres y pacientes acerca de qué condiciones tanto en el hogar como en la escuela deben evitarse para controlar el avance de la respuesta alérgica.
Astrocitoma pilocítico: informe de dos casos con presentación infrecuente
Authors: Aqueche-Peralta Gabriela , Morales Kimberly , Rodríguez-Monzón Astrid , Gramajo Marisol
Published: December 2022

El astrocitoma pilocítico es un tumor de crecimiento lento, compuesto de células tumorales alargadas con localización preferencial en la línea media del Sistema Nervioso Central (SNC). Representa el 6% de todos los tumores intracraneales primarios y el 30% de todos los tumores de fosa posterior infantiles. Según su localización, el 80% ocurre en fosa posterior y se divide en supratentoriales e infratentoriales. Su presentación medular es rara en niños menores de un año. Se presentan dos casos de astrocitoma pilocítico con localización anatómica poco frecuente.
Síndrome clínico aislado en esclerosis múltiple: informe de caso
Authors: Pisquiy-Quemé Ana , García-Bautista Victor
Published: December 2022

La esclerosis múltiple (EM) es la enfermedad desmielinizante inflamatoria, mediada por el sistema inmunitario, más común del sistema nervioso central. Se presenta un caso de esclerosis múltiple en paciente de 25 años de edad, que consultó por pérdida de la visión del ojo izquierdo acompañada de hemiparesia derecha, que se desarrolló de forma aguda, con una duración de más de 24 horas, en ausencia de fiebre o infección. En resonancia magnética cerebral se evidenciaron lesiones hiperintensas que sugirieron evento desmielinizante inflamatorio multifocal. Bandas oligoclonales en suero y líquido cefalorraquídeo positivas. Luego del tratamiento con corticoesteroides, la paciente presentó mejoría clínica.
Carcinoma Cutáneo de Células de Merkel: informe de caso
Authors: Herrera-Capriel Lourdes , Orozco Azuani
Published: December 2022

Se presenta el caso de una paciente femenina de 74 años de edad, con lesión en piel de región malar. Al estudio microscópico se confirmó Carcinoma de Células de Merkel, tumor cutáneo de origen neuroendocrino caracterizado por baja frecuencia y alta malignidad.
Neurocitoma central: informe de 2 casos
Authors: Rodríguez-Monzón Astrid , Aqueche Gabriela , Morales Kimberly , Gramajo Marisol
Published: December 2022

El neurocitoma central es una neoplasia rara, ubicada dentro de los ventrículos laterales, de crecimiento lento, que representa del 0.25 al 0.5% de las lesiones primarias en adultos jóvenes. Tiene un pronóstico favorable posterior a la resección completa. Se realizó una búsqueda de casos en un período de 9 años en el Instituto Guatemalteco de Seguridad Social y se encontraron dos casos de Neurocitoma central en hombres de 19 y 22 años.
Conexión venosa pulmonar anómala total: informe de caso
Authors: Contreras-Camey Gladys , Mazariegos Adriana
Published: December 2022

La conexión venosa anómala total es una cardiopatía congénita en la que no existe continuidad entre el seno venoso pulmonar y la aurícula izquierda, ocasionando que la sangre que llega al seno venoso pulmonar drene en la aurícula derecha. Se presenta el caso de un paciente con cianosis persistente desde el nacimiento, dificultad respiratoria y disminución en saturación de oxígeno, en quien se documentó una conexión venosa anómala total intracardiaca. El diagnóstico ecocardiográfico es de suma importancia para indicar el tratamiento quirúrgico para corregir el defecto.
Síndrome de Holt Oram en paciente pediátrico
Authors: Rivera Irwing , Linares Melissa , Galdámez Isabel , Martínez Celia
Published: December 2022

El síndrome de Holt Oram es un desorden de herencia autosómica dominante, caracterizado por anomalías esqueléticas, cardíacas estructurales y alteraciones en la conducción eléctrica del corazón. Estas alteraciones son secundarias a mutaciones del gen TBX5, gen encargado de codificar la proteína T-box 5 que es importante en la formación de tejidos y órganos durante la embriogénesis. A continuación, se presenta el caso de un paciente masculino que al nacimiento presenta alteraciones anatómicas en ambos miembros superiores, asociadas a soplo cardíaco, por lo cual se sospecha de síndrome de Holt Oram.
Leiomioma uterino submucoso prolapsado causando dolores tipo parto
Authors: Villeda-Alvarez Britizney , Samayoa-Veliz Karla
Published: December 2022

El leiomioma uterino es el tumor benigno más frecuente en las mujeres en edad fértil. Los leiomiomas pueden ser de diferentes tamaños y a veces presentarse como tumores necróticos, degenerados o prolapsados. A continuación, se presenta el caso de una paciente de 37 años, con leiomioma submucoso pediculado y prolapsado.
Asociación entre cesárea y la frecuencia de asma, rinitis alérgica y dermatitis atópica
Authors: Barrón-Balderas Alejandro , González-Mendoza Tania , Pérez-Molina Jesús , Cruz-Revilla Rubén , Del-Río-Hidalgo Rodrigo , Pérez-Robles Mariana , Pérez-Robles Diana , Godínez-Aguiar María , González- Mendoza Diana , Pérez-Robles Armando , Solano-González Karla
Published: December 2022

Antecedentes: la prevalencia de asma, rinitis alérgica (RA) y dermatitis atópica (DA), han incrementado notoriamente y llevado a considerar asociaciones como la vía de nacimiento. Objetivo: determinar la asociación de la frecuencia de asma, RA y DA en niños de 6 a 12 años que asistieron a consulta del Hospital Civil de Guadalajara “Dr. Juan I. Menchaca”. Material y métodos: estudio de casos y controles, con carácter censal no probabilístico. Se utilizó el cuestionario estandarizado y validado del grupo The Internacional Study of Asthma and Allergies in Childhood. Resultados: fueron incluidos 414 sujetos, 52.8% nacidos vía cesárea y 47.2% vía parto. No se encontró asociación entre la vía de nacimiento y la frecuencia de asma, RA y DA. El nacimiento por cesárea estuvo asociado significativamente con RA en hombres (OR: 2.81, IC 95%: 1.189-1.280, p=0.043). La ausencia de lactancia y el humo de tabaco fueron asociados a asma (OR:1.549, IC 95%: 1.086-1.255, p=0.042 y OR: 2.339, IC 95%: 1.243-4.401, p=0.007). Conclusiones: no existe asociación entre la vía de nacimiento y la frecuencia de asma, RA o DA. Hubo asociación con la cesárea y la frecuencia de RA en hombres a su vez, la lactancia y el tabaco fueron asociados a asma
Atresia esofágica con fístula traqueoesofágica distal en centro hospitalario de tercer nivel
Authors: Hidalgo-Lone Jorge , Castillo-Orellana Cynthia
Published: December 2022

Se presenta caso de paciente femenina de 36 semanas de edad gestacional, producto de cesárea, con peso al nacimiento de 1.56kg y APGAR 6-8, quien a su evaluación física inmediata se sospecha de atresia esofágica por ausencia de paso de sonda orogástrica para aspirado de contenido gástrico y antecedente materno de polihidramnios con drenaje de aproximadamente 2800ml de líquido amniótico durante cesárea. Paciente es ingresada y se realizan estudios complementarios para malformaciones de la línea media, detectando cardiopatía congénita. Paciente es llevada a sala de operaciones para corrección de defecto esofágico, tras lo cual es trasladada a área de cuidados críticos.
Variaciones geográficas de morbilidad por COVID-19 en El Salvador: análisis estadístico espacial con SaTScan
Authors: Bonilla-Carrión Roger
Published: December 2022

Antecedentes: El COVID-19 es un problema de salud pública en los países en vías de desarrollo, incluyendo El Salvador. Muchos estudios han investigado acerca de la epidemiología y tratamiento del COVID-19, pero pocos han informado sobre la distribución geográfica del COVID-19, la variabilidad y agrupamiento espacial, para diseñar políticas de salud a nivel local. Objetivo: El objetivo de este estudio es investigar la variabilidad y agrupamiento espacial de morbilidad por COVID-19 en El Salvador. Métodos: Se realizó una revisión retrospectiva de los registros de COVID-19 utilizando datos informados al Ministerio de Salud del gobierno de El Salvador entre el 13 de Marzo del 2020 y el 13 de Junio del 2022. Se incluyeron y geocodificaron 261 municipios en el estudio y se utilizaron estadísticas espaciales de exploración espacial para identificar clústeres de COVID-19. Los análisis estadísticos se realizaron utilizando los programas Microsoft EXCEL y SaTScan y los mapas se realizaron usando el programa R. Resultados: La morbilidad por COVID-19 en El Salvador presentó evidencia estadística de agrupamiento espacial. Se encontraron cinco clústeres puramente espaciales muy probables en San Salvador (RR=2.22, p=0.00), San Miguel (RR=2.25, p=0.00), Santa Ana (RR=1.82, p=0.00), Chalatenango (RR=2.85, p=0.00) y Nombre de Jesús (RR=1.57, p=0.00). Conclusión: La COVID-19 no ocurrió al azar, sino que presentó heterogeneidad espacial. Se recomienda tomar en cuenta la heterogeneidad espacial identificada en los clústeres para la prevención y el control del COVID-19.
Tumor fibroso solitario del sistema nervioso central: informe de caso
Authors: Perez Karen , Rodas Boanerges , Medina Pebbles
Published: December 2022

El Tumor Fibroso Solitario (TFS) es una entidad poco descrita en el sistema nervioso central (SNC). Es una neoplasia de origen mesenquimatoso, vascularizada, fácilmente confundida con meningiomas por estudios de imagen, de manifestaciones clínicas inespecíficas. La inmunohistoquímica es fundamental para confirmar su diagnóstico y definir pronóstico. Se presenta el caso de una paciente de 66 años de edad, cuyo tumor fue consultado al departamento de patología del Hospital General San Juan de Dios para diagnóstico.
Ingestión de cuerpos extraños. Informe de 5 casos en edad pediátrica
Authors: Galindo-Amador Andrea , Rivera-Andrade Silvia , Ortiz-Guerra Marco
Published: December 2022

La ingestión de cuerpo extraño en pediatría, en ocasiones, necesita tratamiento endoscópico de urgencia. Una de las complicaciones más graves y temidas es la perforación esofágica, la cual puede ocurrir según la forma y el material del objeto ingerido. En el siguiente artículo presentamos una serie de 5 casos documentados en el departamento de Zacapa, de Octubre del 2021 a Junio del 2022. El diagnóstico se basó en una buena historia clínica, estudios de radio imágenes y una intervención oportuna mediante endoscopía.
Nevo de Becker: informe de caso
Authors: Marroquín-Remón Rosmin , Lima-Franco Alexandro
Published: December 2022

A continuación se presenta el caso de un paciente masculino de 23 años de edad, sin antecedentes médicos de importancia, quien acude a consulta por mancha con vellos en hombro izquierdo de 8 años de evolución.
Rinoescleroma: una enfermedad endémica en Guatemala
Authors: Morán-Mejía Javier , Argueta Víctor , Orozco Roberto
Published: December 2022

Introducción: el rinoescleroma es una enfermedad granulomatosa crónica que afecta el tracto respiratorio superior, principalmente las fosas nasales y progresa lentamente. El diagnóstico histológico se confirma por la demostración de células típicas de Mikulicz, infiltrado linfoplasmocítico y cuerpos de Russell. Objetivo: conocer la situación actual de rinoescleroma en nuestro hospital y compararla con estudios previos del país, para determinar la tendencia de su frecuencia. Material y métodos: estudio retrospectivo realizado durante el periodo de abril de 2010 a marzo de 2021, en el Hospital General San Juan De Dios de la ciudad de Guatemala. Resultados: se incluyeron 11 casos, 8 mujeres y 3 hombres, con una edad promedio de 28 años. Conclusión: la importancia de este estudio es que a pesar de que es una entidad que ha disminuido considerablemente, en el país sigue siendo endémica
Anemia hemolítica autoinmune por cuerpos fríos secundarios a SARS-CoV-2 en una adolescente
Authors: Quijada Kevin , Torselli Silvana
Published: December 2022

Las anemias hemolíticas autoinmunes (AHA) son desórdenes adquiridos, en los cuales disminuye la vida media de los eritrocitos por autodestrucción. Pueden ser primarias por autoinmunidad o secundarias debido a una enfermedad que forma auto anticuerpos contra la membrana de eritrocitos. Las AHA se consideran de cuerpos fríos cuando están mediadas por IgM y ocurre destrucción de eritrocitos a 4ºC en el contexto de una infección. Se presenta el caso de una paciente de 13 años de edad, con hemoglobina en 3g/dL, sin antecedentes médicos relevantes, sin vacunación para COVID-19, con hisopado nasofaríngeo PCR positivo para SARS-CoV-2 y test de aglutininas frías, positivo.
Linitis plástica gástrica en una paciente de 58 años de edad
Authors: Molina Kevin , Sifontes Rina , Bech Stefan
Published: December 2022

Se conoce como linitis plástica al aspecto macroscópico engrosado y rígido que presentan los órganos invadidos por adenocarcinoma de tipo difuso, el cual, en el estómago suele respetar la mucosa. Se presenta el caso de una paciente de 58 años de edad, con diagnóstico de linitis plástica gástrica con presentación atípica.
Diagnóstico y manejo de un caso de siameses toracópagos
Authors: Villeda-Alvarez Britizney
Published: December 2022

Los siameses son gemelos monocigotos unidos por uno de los polos embrionarios. Constituyen una desviación del desarrollo embrionario. Su mortalidad es alta, relacionada con la afectación de órganos vitales y porque además se asocian a malformaciones complejas incompatibles con la vida, ya sea por el defecto estructural o por el daño funcional. La variante más frecuente es la toracópago, donde aparecen los gemelos cara a cara fusionados en diferentes zonas del tórax.
Síndrome anticolinérgico secundario al consumo de infusión de “Flor de Campana”, informe de caso
Authors: Pisquiy-Quemé Ana
Published: December 2022

El síndrome anticolinérgico (SA) es una complicación secundaria al empleo de fármacos o sustancias anticolinérgicas con efecto antimuscarínico. Se presenta el caso de paciente masculino de 57 años de edad, sin antecedentes médicos previos, quien cursó con SA posterior al consumo de infusión Flor de Campana del género Brugmansia. La escopolamina y atropina, que tienen un efecto anticolinérgico, son los alcaloides causantes de los problemas tóxicos y psicóticos que se presentan al consumir altas dosis de este género o al estar expuesto durante un tiempo prolongado.
Miocardiopatía restrictiva por amiloidosis cardiaca: informe de caso
Authors: Gómez José , Tereta Romeo , Herrera Lubeck , Gutiérrez Rodolfo
Published: December 2022

La amiloidosis cardíaca es un trastorno causado por el depósito de fibrillas de amiloide en el espacio extracelular de miocardio, se presenta con insuficiencia cardíaca con función sistólica conservada y progresa a una fisiología restrictiva típica,  síncopes, fibrilación auricular o muerte súbita. La ecocardiografía es la prueba de imagen cardíaca de primera línea. La infiltración de las paredes ventriculares produce una apariencia de hipertrofia con ventrículos no dilatados o pequeños. Para el diagnóstico se emplean la identificación de proteína monoclonal y biopsia de tejido con infiltración de amiloide. La mayoría de pacientes progresa a insuficiencia cardíaca terminal
Paciente femenina de 12 años con fiebre luego de viaje a Petén, Guatemala
Authors: Galdámez-Díaz Sergio , Gebhardt-Quan Christian
Published: December 2022

Plasmodium vivax es el parásito causante de malaria con la mayor distribución mundial, se calcula que 2.5 billones de personas se encuentran en riesgo de contraer la infección, y se estima que hay de 80 a 300 millones de casos al año. Guatemala no es la excepción, hasta la 33 semana del 2020 se reportaron 504 casos de malaria, siendo Escuintla, Alta Verapaz y Petén los 3 departamentos con mayor prevalencia. Presentamos un caso de Paludismo en paciente que viajó a Petén, en el norte de Guatemala,  dos semanas antes del inicio de los síntomas.