bluuebunny/crossref_metadata_2025 huggingface dataset:
Cell and Signal Components of the Microenvironment of Bone Metastasis Are Affected by Hypoxia
Authors: Bendinelli Paola , Maroni Paola , Matteucci Emanuela , Desiderio Maria
Published: May 2016

Bone metastatic cells release bone microenvironment proteins, such as the matricellular protein SPARC (secreted protein acidic and rich in cysteine), and share a cell signaling typical of the bone metabolism controlled by Runx2. The megakaryocytes in the bone marrow engrafted by the metastases seem to be one of the principal microenvironment sources of the biological stimuli, implicated in the formation of an osteoblastic niche, and affecting metastasis phenotype and colonization. Educated platelets in the circulation might derive from megakaryocytes in bone metastasis. The evaluation of predictive markers in the circulating platelets might be useful for the stratification of patients for therapeutic purposes. The hypoxic environment in bone metastasis is one of the key regulators of the network of the biological soluble and structural components of the matrix. In bone metastatic cells under hypoxia, similar patterns of Runx2 and SPARC are observed, both showing downregulation. Conversely, hypoxia induces Endothelin 1, which upregulates SPARC, and these biological stimuli may be considered prognostic markers of bone metastasis in breast carcinoma patients.
Expression and Function of miR-155 in Diseases of the Gastrointestinal Tract
Authors: Wan Jianhua , Xia Liang , Xu Wenting , Lu Nonghua
Published: May 2016

MicroRNAs (miRNAs) are a type of small noncoding RNA that can regulate the expression of target genes under physiological and pathophysiological conditions. miR-155 is a multifunctional miRNA with inflammation-related and oncogenic roles. In particular, the dysregulation of miR-155 has been strongly implicated in Helicobacter pylori-related gastric disease, inflammatory bowel disease, and colorectal cancer in addition to being involved in molecular changes of important targets and signaling pathways. This review focuses on the expression and function of miR-155 during inflammation and carcinogenesis and its potential use as an effective therapeutic target for certain gastrointestinal diseases.
Preparation and Characterization of Flexible Substrate Material from Phenyl-Thiophene-2-Carbaldehyde Compound
Authors: Rahman Ashiqur , Islam Mohammad , Samsuzzaman Md , Singh Mandeep , Akhtaruzzaman Md.
Published: May 2016

In this paper, a novel phenyl-thiophene-2-carbaldehyde compound-based flexible substrate material has been presented. Optical and microwave characterization of the proposed material are done to confirm the applicability of the proposed material as a substrate. The results obtained in this work show that the phenyl-thiophene-2-carbaldehyde consists of a dielectric constant of 3.03, loss tangent of 0.003, and an optical bandgap of 3.24 eV. The proposed material is analyzed using commercially available EM simulation software and validated by the experimental analysis of the flexible substrate. The fabricated substrate also shows significant mechanical flexibility and light weight. The radiating copper patch deposited on the proposed material substrate incorporated with partial ground plane and microstrip feeding technique shows an effective impedance bandwidth of 3.8 GHz. It also confirms an averaged radiation efficiency of 81% throughout the frequency band of 5.4–9.2 GHz.
Effect of Experimental Parameters on Alginate/Chitosan Microparticles for BCG Encapsulation
Authors: Caetano Liliana , Almeida António , Gonçalves Lídia
Published: May 2016

The aim of the present study was to develop novel Mycobacterium bovis bacille Calmette-Guérin (BCG)-loaded polymeric microparticles with optimized particle surface characteristics and biocompatibility, so that whole live attenuated bacteria could be further used for pre-exposure vaccination against Mycobacterium tuberculosis by the intranasal route. BCG was encapsulated in chitosan and alginate microparticles through three different polyionic complexation methods by high speed stirring. For comparison purposes, similar formulations were prepared with high shear homogenization and sonication. Additional optimization studies were conducted with polymers of different quality specifications in a wide range of pH values, and with three different cryoprotectors. Particle morphology, size distribution, encapsulation efficiency, surface charge, physicochemical properties and biocompatibility were assessed. Particles exhibited a micrometer size and a spherical morphology. Chitosan addition to BCG shifted the bacilli surface charge from negative zeta potential values to strongly positive ones. Chitosan of low molecular weight produced particle suspensions of lower size distribution and higher stability, allowing efficient BCG encapsulation and biocompatibility. Particle formulation consistency was improved when the availability of functional groups from alginate and chitosan was close to stoichiometric proportion. Thus, the herein described microparticulate system constitutes a promising strategy to deliver BCG vaccine by the intranasal route.
Anti-Oxidative Activity of Mytiloxanthin, a Metabolite of Fucoxanthin in Shellfish and Tunicates
Authors: Maoka Takashi , Nishino Azusa , Yasui Hiroyuki , Yamano Yumiko , Wada Akimori
Published: May 2016

Anti-oxidative activities of mytiloxanthin, a metabolite of fucoxanthin in shellfish and tunicates, were investigated. Mytiloxanthin showed almost the same activities for quenching singlet oxygen and the inhibition of lipid peroxidation as those of astaxanthin, which is a well-known singlet oxygen quencher. Furthermore, mytiloxanthin showed excellent scavenging activity for hydroxyl radicals and this activity was markedly higher than that of astaxanthin.
Linking Findings in Microfluidics to Membrane Emulsification Process Design: The Importance of Wettability and Component Interactions with Interfaces
Authors: Schroën Karin , Ferrando Montse , De Lamo-Castellví Silvia , Sahin Sami , Güell Carme
Published: May 2016

In microfluidics and other microstructured devices, wettability changes, as a result of component interactions with the solid wall, can have dramatic effects. In emulsion separation and emulsification applications, the desired behavior can even be completely lost. Wettability changes also occur in one phase systems, but the effect is much more far-reaching when using two-phase systems. For microfluidic emulsification devices, this can be elegantly demonstrated and quantified for EDGE (Edge-base Droplet GEneration) devices that have a specific behavior that allows us to distinguish between surfactant and liquid interactions with the solid surface. Based on these findings, design rules can be defined for emulsification with any micro-structured emulsification device, such as direct and premix membrane emulsification. In general, it can be concluded that mostly surface interactions increase the contact angle toward 90°, either through the surfactant, or the oil that is used. This leads to poor process stability, and very limited pressure ranges at which small droplets can be made in microfluidic systems, and cross-flow membrane emulsification. In a limited number of cases, surface interactions can also lead to lower contact angles, thereby increasing the operational stability. This paper concludes with a guideline that can be used to come to the appropriate combination of membrane construction material (or any micro-structured device), surfactants and liquids, in combination with process conditions.
The Effect of Phenazine-1-Carboxylic Acid on the Morphological, Physiological, and Molecular Characteristics of Phellinus noxius
Authors: Huang Huazhi , Sun Longhua , Bi Keke , Zhong Guohua , Hu Meiying
Published: May 2016

In this study, the effect of phenazine-1-carboxylic acid (PCA) on morphological, physiological, and molecular characteristics of Phellinus noxius has been investigated, and the potential antifungal mechanism of PCA against P. noxius was also explored. The results revealed that PCA showed in vitro antifungal potential against P. noxius and completely inhibited P. noxius hyphae at concentrations >40 μg/mL. PCA inhibited both mycelial growth and the loss of mycelial biomass in vitro in a dose-dependent manner. Morphological changes in PCA-treated P. noxius hyphae, such as irregularly swollen mycelia as well as short hyphae with increased septation and less branching, were observed by optical microscopy. The intracellular reactive oxygen species (ROS) levels were significantly increased in PCA-treated P. noxius cells as compared to control groups. Induced hyperpolarization of the mitochondrial membrane potential (MMP), repressed superoxide dismutase (SOD) activity and up-regulated gene expression of seven tested genes were also found in PCA-treated P. noxius groups. Thus, the present results suggested that the mechanism of action of PCA against P. noxius might be attributed to direct damage of mycelium and high intracellular ROS production, and indirect induction of genes involved in cell detoxification, oxidation-reduction process, and electron transport of the respiratory chain.
Efficient Synthesis of the Lewis A Tandem Repeat
Authors: Kobayashi Daisuke , Ueki Akiharu , Yamaji Tomoya , Nagao Kazuya , Imamura Akihiro , Ando Hiromune , Kiso Makoto , Ishida Hideharu
Published: May 2016

The convergent synthesis of the Lewis A (Lea) tandem repeat is described. The Lea tandem repeat is a carbohydrate ligand for a mannose binding protein that shows potent inhibitory activity against carcinoma growth. The Lea unit, {β-d-Gal-(1→3)-[α-l-Fuc-(1→4)]-β-d-GlcNAc}, was synthesized by stereoselective nitrile-assisted β-galactosylation with the phenyl 3-O-allyl-2,4,6-tri-O-benzyl-1-thio-β-galactoside, and ether-assisted α-fucosylation with fucosyl (N-phenyl)trifluoroacetimidate. This common Lea unit was easily converted to an acceptor and donor in high yields, and the stereoselective assembly of the hexasaccharide and dodecasaccharide as the Lea tandem repeat framework was achieved by 2-trichloroacetamido-assisted β-glycosylation and the (N-phenyl)trifluoroacetimidate method.
Synthesis and Biological Testing of Novel Glucosylated Epigallocatechin Gallate (EGCG) Derivatives
Authors: Zhang Xin , Wang Jing , Hu Jiang-Miao , Huang Ye-Wei , Wu Xiao-Yun , Zi Cheng-Ting , Wang Xuan-Jun , Sheng Jun
Published: May 2016

Epigallocatechin gallate (EGCG) is the most abundant component of green tea catechins and has strong physiological activities. In this study, two novel EGCG glycosides (EGCG-G1 and EGCG-G2) were chemoselectively synthesized by a chemical modification strategy. Each of these EGCG glycosides underwent structure identification, and the structures were assigned as follows: epigallocatechin gallate-4′′-O-β-d-glucopyranoside (EGCG-G1, 2) and epigallocatechin gallate-4′,4′′-O-β-d-gluco-pyranoside (EGCG-G2, 3). The EGCG glycosides were evaluated for their anticancer activity in vitro against two human breast cell lines (MCF-7 and MDA-MB-231) using MTT assays. The inhibition rate of EGCG glycosides (EGCG-G1 and EGCG-G2) is not obvious. The EGCG glycosides are more stable than EGCG in aqueous solutions, but exhibited decreasing antioxidant activity in the DPPH radical-scavenging assay (EGCG > EGCG-G2 > EGCG-G1). Additionally, the EGCG glycosides exhibited increased water solubility: EGCG-G2 and EGCG-G1 were 15 and 31 times as soluble EGCG, respectively. The EGCG glycosides appear to be useful, and further studies regarding their biological activity are in progress.
First in-Flight Radiometric Calibration of MUX and WFI on-Board CBERS-4
Authors: Pinto Cibele , Ponzoni Flávio , Castro Ruy , Leigh Larry , Mishra Nischal , Aaron David , Helder Dennis
Published: May 2016

Brazil and China have a long-term joint space based sensor program called China-Brazil Earth Resources Satellite (CBERS). The most recent satellite of this program (CBERS-4) was successfully launched on 7 December 2014. This work describes a complete procedure, along with the associated uncertainties, used to calculate the in-flight absolute calibration coefficients for the sensors Multispectral Camera (MUX) and Wide-Field Imager (WFI) on-board CBERS-4. Two absolute radiometric calibration techniques were applied: (i) reflectance-based approach and (ii) cross-calibration method. A specific site at Algodones Dunes region located in the southwestern portion of the United States of America was used as a reference surface. Radiometric ground and atmospheric measurements were carried out on 9 March 2015, when CBERS-4 passed over the region. In addition, a cross-calibration between both MUX and WFI on-board CBERS-4 and the Operational Land Imager (OLI) on-board Landsat-8 was performed using the Libya-4 Pseudo Invariant Calibration Site. The gain coefficients are now available: 1.68, 1.62, 1.59 and 1.42 for MUX and 0.379, 0.498, 0.360 and 0.351 for WFI spectral bands blue, green, red and NIR, respectively, in units of (W/(m2·sr·μm))/DN. These coefficients were determined with uncertainties lower than 3.5%. As a validation of these radiometric coefficients, cross-calibration was also undertaken. An evaluation of radiometric consistency was performed between the two instruments (MUX and WFI) on-board CBERS-4 and with the well calibrated Landsat-7 ETM+. Results show that the reflectance values match in all the analogous spectral bands within the specified calibration uncertainties.
Modeling of a Single-Notch Microfiber Coupler for High-Sensitivity and Low Detection-Limit Refractive Index Sensing
Authors: Zhang Jiali , Shi Lei , Zhu Song , Xu Xinbiao , Zhang Xinliang
Published: May 2016

A highly sensitive refractive index sensor with low detection limit based on an asymmetric optical microfiber coupler is proposed. It is composed of a silica optical microfiber and an As2Se3 optical microfiber. Due to the asymmetry of the microfiber materials, a single-notch transmission spectrum is demonstrated by the large refractive index difference between the two optical microfibers. Compared with the symmetric coupler, the bandwidth of the asymmetric structure is over one order of magnitude narrower than that of the former. Therefore, the asymmetric optical microfiber coupler based sensor can reach over one order of magnitude smaller detection limit, which is defined as the minimal detectable refractive index change caused by the surrounding analyte. With the advantage of large evanescent field, the results also show that a sensitivity of up to 3212 nm per refractive index unit with a bandwidth of 12 nm is achieved with the asymmetric optical microfiber coupler. Furthermore, a maximum sensitivity of 4549 nm per refractive index unit can be reached while the radii of the silica optical microfiber and As2Se3 optical microfiber are 0.5 μm and a 0.128 μm, respectively. This sensor component may have important potential for low detection-limit physical and biochemical sensing applications.
Bootstrapping Security Policies for Wearable Apps Using Attributed Structural Graphs
Authors: González-Tablas Ana , Tapiador Juan
Published: May 2016

We address the problem of bootstrapping security and privacy policies for newly-deployed apps in wireless body area networks (WBAN) composed of smartphones, sensors and other wearable devices. We introduce a framework to model such a WBAN as an undirected graph whose vertices correspond to devices, apps and app resources, while edges model structural relationships among them. This graph is then augmented with attributes capturing the features of each entity together with user-defined tags. We then adapt available graph-based similarity metrics to find the closest app to a new one to be deployed, with the aim of reusing, and possibly adapting, its security policy. We illustrate our approach through a detailed smartphone ecosystem case study. Our results suggest that the scheme can provide users with a reasonably good policy that is consistent with the user’s security preferences implicitly captured by policies already in place.
Spectrum and Image Texture Features Analysis for Early Blight Disease Detection on Eggplant Leaves
Authors: Xie Chuanqi , He Yong
Published: May 2016

This study investigated both spectrum and texture features for detecting early blight disease on eggplant leaves. Hyperspectral images for healthy and diseased samples were acquired covering the wavelengths from 380 to 1023 nm. Four gray images were identified according to the effective wavelengths (408, 535, 624 and 703 nm). Hyperspectral images were then converted into RGB, HSV and HLS images. Finally, eight texture features (mean, variance, homogeneity, contrast, dissimilarity, entropy, second moment and correlation) based on gray level co-occurrence matrix (GLCM) were extracted from gray images, RGB, HSV and HLS images, respectively. The dependent variables for healthy and diseased samples were set as 0 and 1. K-Nearest Neighbor (KNN) and AdaBoost classification models were established for detecting healthy and infected samples. All models obtained good results with the classification rates (CRs) over 88.46% in the testing sets. The results demonstrated that spectrum and texture features were effective for early blight disease detection on eggplant leaves.
Carrying Position Independent User Heading Estimation for Indoor Pedestrian Navigation with Smartphones
Authors: Deng Zhi-An , Wang Guofeng , Hu Ying , Cui Yang
Published: May 2016

This paper proposes a novel heading estimation approach for indoor pedestrian navigation using the built-in inertial sensors on a smartphone. Unlike previous approaches constraining the carrying position of a smartphone on the user’s body, our approach gives the user a larger freedom by implementing automatic recognition of the device carrying position and subsequent selection of an optimal strategy for heading estimation. We firstly predetermine the motion state by a decision tree using an accelerometer and a barometer. Then, to enable accurate and computational lightweight carrying position recognition, we combine a position classifier with a novel position transition detection algorithm, which may also be used to avoid the confusion between position transition and user turn during pedestrian walking. For a device placed in the trouser pockets or held in a swinging hand, the heading estimation is achieved by deploying a principal component analysis (PCA)-based approach. For a device held in the hand or against the ear during a phone call, user heading is directly estimated by adding the yaw angle of the device to the related heading offset. Experimental results show that our approach can automatically detect carrying positions with high accuracy, and outperforms previous heading estimation approaches in terms of accuracy and applicability.
Assessment of Aliasing Errors in Low-Degree Coefficients Inferred from GPS Data
Authors: Wei Na , Fang Rongxin
Published: May 2016

With sparse and uneven site distribution, Global Positioning System (GPS) data is just barely able to infer low-degree coefficients in the surface mass field. The unresolved higher-degree coefficients turn out to introduce aliasing errors into the estimates of low-degree coefficients. To reduce the aliasing errors, the optimal truncation degree should be employed. Using surface displacements simulated from loading models, we theoretically prove that the optimal truncation degree should be degree 6–7 for a GPS inversion and degree 20 for combing GPS and Ocean Bottom Pressure (OBP) with no additional regularization. The optimal truncation degree should be decreased to degree 4–5 for real GPS data. Additionally, we prove that a Scaled Sensitivity Matrix (SSM) approach can be used to quantify the aliasing errors due to any one or any combination of unresolved higher degrees, which is beneficial to identify the major error source from among all the unresolved higher degrees. Results show that the unresolved higher degrees lower than degree 20 are the major error source for global inversion. We also theoretically prove that the SSM approach can be used to mitigate the aliasing errors in a GPS inversion, if the neglected higher degrees are well known from other sources.
Absolute Position Sensing Based on a Robust Differential Capacitive Sensor with a Grounded Shield Window
Authors: Bai Yang , Lu Yunfeng , Hu Pengcheng , Wang Gang , Xu Jinxin , Zeng Tao , Li Zhengkun , Zhang Zhonghua , Tan Jiubin
Published: May 2016

A simple differential capacitive sensor is provided in this paper to measure the absolute positions of length measuring systems. By utilizing a shield window inside the differential capacitor, the measurement range and linearity range of the sensor can reach several millimeters. What is more interesting is that this differential capacitive sensor is only sensitive to one translational degree of freedom (DOF) movement, and immune to the vibration along the other two translational DOFs. In the experiment, we used a novel circuit based on an AC capacitance bridge to directly measure the differential capacitance value. The experimental result shows that this differential capacitive sensor has a sensitivity of 2 × 10−4 pF/μm with 0.08 μm resolution. The measurement range of this differential capacitive sensor is 6 mm, and the linearity error are less than 0.01% over the whole absolute position measurement range.
Environmental Regulation, Economic Network and Sustainable Growth of Urban Agglomerations in China
Authors: Chong Zhaohui , Qin Chenglin , Ye Xinyue
Published: May 2016

In this paper, we examine the influence of environmental regulation on sustainable economic growth from both theoretical and empirical perspectives. Our research is twofold. First, we apply a modified NEG (New Economic Geography) model to analyze how environmental regulation influences firms’ location choices and cities’ sustainable economic growth. Second, we test a spatial econometric model employing panel data of the three largest urban agglomerations in China from 2003 to 2013 to study the relationship between environmental regulation and sustainable economic growth as well as the spillover channels of economic activities. The results reveal a remarkable negative effect of environmental regulation on economic growth. In addition, we find no sufficient evidence to prove the existence of long-term effects of environmental regulation on economic growth in the three urban agglomerations. Furthermore, using different weight matrices to illustrate the different economic networks of the urban agglomeration, we validate the difference in spillover mechanisms across these three urban agglomerations. Specifically, the disparity in environmental regulation acts as a spillover channel for the Yangtze River Delta and the Pearl River Delta, while it is not significant for Jing-Jin-Ji.
The Draft Genome Sequence of the Yersinia entomophaga Entomopathogenic Type Strain MH96T
Authors: Hurst Mark , Beattie Amy , Altermann Eric , Moraga Roger , Harper Lincoln , Calder Joanne , Laugraud Aurelie
Published: May 2016

Here we report the draft genome of Yersinia entomophaga type strain MH96T. The genome shows 93.8% nucleotide sequence identity to that of Yersinia nurmii type strain APN3a-cT, and comprises a single chromosome of approximately 4,275,531 bp. In silico analysis identified that, in addition to the previously documented Y. entomophaga Yen-TC gene cluster, the genome encodes a diverse array of toxins, including two type III secretion systems, and five rhs-associated gene clusters. As well as these multicomponent systems, several orthologs of known insect toxins, such as VIP2 toxin and the binary toxin PirAB, and distant orthologs of some mammalian toxins, including repeats-in-toxin, a cytolethal distending toxin, hemolysin-like genes and an adenylate cyclase were identified. The genome also contains a large number of hypothetical proteins and orthologs of known effector proteins, such as LopT, as well as genes encoding a wide range of proteolytic determinants, including metalloproteases and pathogen fitness determinants, such as genes involved in iron metabolism. The bioinformatic data derived from the current in silico analysis, along with previous information on the pathobiology of Y. entomophaga against its insect hosts, suggests that a number of these virulence systems are required for survival in the hemocoel and incapacitation of the insect host.
Correspondence of Neutralizing Humoral Immunity and CD4 T Cell Responses in Long Recovered Sudan Virus Survivors
Authors: Sobarzo Ariel , Stonier Spencer , Herbert Andrew , Ochayon David , Kuehne Ana , Eskira Yael , Fedida-Metula Shlomit , Tali Neta , Lewis Eli , Egesa Moses , Cose Stephen , Lutwama Julius , Yavelsky Victoria , Dye John , Lobel Leslie
Published: May 2016

Robust humoral and cellular immunity are critical for survival in humans during an ebolavirus infection. However, the interplay between these two arms of immunity is poorly understood. To address this, we examined residual immune responses in survivors of the Sudan virus (SUDV) outbreak in Gulu, Uganda (2000–2001). Cytokine and chemokine expression levels in SUDV stimulated whole blood cultures were assessed by multiplex ELISA and flow cytometry. Antibody and corresponding neutralization titers were also determined. Flow cytometry and multiplex ELISA results demonstrated significantly higher levels of cytokine and chemokine responses in survivors with serological neutralizing activity. This correspondence was not detected in survivors with serum reactivity to SUDV but without neutralization activity. This previously undefined relationship between memory CD4 T cell responses and serological neutralizing capacity in SUDV survivors is key for understanding long lasting immunity in survivors of filovirus infections.
Centenaire et républicanisme : 1889 dans le Pas-de-Calais et le Nord
Authors: Crogiez Michèle
Published: May 2016

Cette étude a pour but de cerner quelle fut l'attitude des deux départements lors du Centenaire de 1789- On analyse ici dans la presse locale et les archives préfectorales comment le Centenaire s'est organisé ; on tente de mesurer ses soutiens officiels d'une part et de l'autre les réticences des opposants qui perçoivent clairement que l'enjeu de la commémoration est de souder le pays dans une adhésion au régime républicain, dans la perspective des élections d'octobre. La célébration connaît deux temps forts : le 5 mai, souvenir moins violent qui porte l'espoir de rallier le plus grand nombre, et le 14 Juillet, fête nationale encore controversée. Le voyage du président Carnot ajoute, dans le Pas-de-Calais, une occasion de célébrer conjointement la Révolution et la République. On montre comment, lors de ces fêtes, les républicains autant que les opposants travaillent à donner aux événements du passé un sens qui serve leurs intérêts politiques du moment : tous les jugements sur la Révolution sont véhéments, car ils portent en fait sur la situation politique de 1889. Car commémorer c'est demander à l'histoire, schématisée et orientée, de légitimer un régime politique.
Mortalité par accident dans les mines de charbon en Belgique aux XIXe-XXe siècles
Authors: Leboutte René
Published: May 2016

A l'aide des relevés statistiques dressés annuellement par l'Administration des Mines, la mortalité par accident dans les mines belges a pu être retracée depuis 1821 jusque 1985. Si le temps est à la baisse (de 33 tués pour 10.000 ouvriers en 1851-1855, le taux de mortalité est tombé à 6 en 1981-1985). Cette amélioration de la sécurité s'est réalisée lentement, par étapes, grâce au développement des techniques et de la législation.

La confrontation des statistiques belges avec celles de la France, de la Grande- Bretagne, de la Prusse et des Etats-Unis, fait apparaître le retard de ces deux derniers par rapport aux premiers en matière de sécurité minière. La principale explication réside dans l'absence de tradition professionnelle de la main-d'œuvre aux Etats-Unis et en Prusse.

Enfin, l'essor des techniques de sauvetage est également pris en compte afin d'expliquer la réduction de la mortalité à partir de 1890.
Les consultations électorales de 1945 en Picardie
Authors: Besse Jean Pierre
Published: May 2016

En 1945, les Françaises et les Français sont appelés quatre fois aux urnes pour renouveler successivement les conseils municipaux, élus dix ans plus tôt, les conseils généraux et pour élire des députés.

Les municipales du printemps sont un succès pour le parti communiste et surtout pour la S.F.I. O. La droite maintient ses positions. Le parti radical-socialiste, en recul, limite les dégâts. Les cantonales et les législatives de l'automne confirment et accentuent les tendances révélées par les municipales.

Les élections de 1945 ont donc dessiné une nouvelle carte politique de la région en accentuant son orientation à gauche. Elles traduisent en outre un renouvellement profond du personnel politique au profit des hommes et des forces qui ont participé activement à la Résistance.
RESEARCH METHODS IDENTIFYING CORRELATION BETWEEN PHYSICAL ENVIRONMENT OF SCHOOLS AND EDUCATIONAL PARADIGMS / MOKYKLŲ FIZINĖS APLINKOS IR UGDYMO NUOSTATŲ SĄSAJŲ TYRIMAI
Authors: Brukštutė Grėtė
Published: May 2016

The article is analysing the research that was already carried out in order to determine correlation between a physical environment of schools and educational paradigms. While selecting materials for the analysis, the attention was focused on studies conducted in the USA and European countries. Based on these studies the methodological attitudes towards coherence of the education and spatial structures were tried to identify. Homogeneity and conformity of an educational character and a physical learning environment became especially important during changes of educational conceptions. The issue how educational paradigms affect the architecture of school buildings is not yet analysed in Lithuania, therefore the results of this research could actualize a theme on correlation between educational paradigms and the architecture of school buildings and form initial guidelines for the development of the modern physical learning environment. Straipsnyje nagrinėjami jau atlikti tyrimai ugdymo nuostatų ir mokyklų architektūros koreliacijos tema. Renkant medžiagą buvo gilinamasi į JAV ir Europos šalyse atliktus tyrimus, pagal kuriuos buvo bandomos identifikuoti ugdymo ir erdvinių struktūrų sąsajų metodologinės nuostatos. Ugdymo pobūdžio ir fizinės mokymosi aplinkos atitikimas ir vienalytiškumas ypač tampa svarbus ugdymo koncepcijų kaitos metu. Lietuvoje nėra analizuojama, kaip švietimo nuostatos veikia mokyklų architektūrą, todėl šio tyrimo rezultatai aktualizuotų ugdymo paradigmų ir mokyklų architektūros sąsajų temą ir suformuotų pirmines nuorodas modernios ugdymo fizinės aplinkos radimuisi.
KELT-14b AND KELT-15b: AN INDEPENDENT DISCOVERY OF WASP-122b AND A NEW HOT JUPITER
Authors: Rodriguez Joseph E. , Colón Knicole D. , Stassun Keivan G. , Wright Duncan , Cargile Phillip A. , Bayliss Daniel , Pepper Joshua , Collins Karen A. , Kuhn Rudolf B. , Lund Michael B. , Siverd Robert J. , Zhou George , Gaudi B. Scott , Tinney C. G. , Penev Kaloyan , Tan T. G. , Stockdale Chris , Curtis Ivan A. , James David , Udry Stephane , Segransan Damien , Bieryla Allyson , Latham David W. , Beatty Thomas G. , Eastman Jason D. , Myers Gordon , Bartz Jonathan , Bento Joao , Jensen Eric L. N. , Oberst Thomas E. , Stevens Daniel J.
Published: May 2016

We report the discovery of KELT-14b and KELT-15b, two hot Jupiters from the KELT-South survey. KELT-14b, an independent discovery of the recently announced WASP-122b, is an inflated Jupiter mass planet that orbits a

∼

5.0

−
0.7

+
0.3

Gyr, V = 11.0, G2 star that is near the main sequence turnoff. The host star, KELT-14 (TYC 7638-981-1), has an inferred mass

M

*

=

1.18

−
0.07

+
0.05

M
⊙ and radius

R

*

=

1.37
±
−
0.08

R
⊙, and has

T

eff

 =

5802

−
92

+
95

K,

log

g

*

=

4.23

−
0.04

+
0.05

and

[

Fe

/

H

]

 = 0.33 ± −0.09. The planet orbits with a period of 1.7100588 ± 0.0000025 days (T
0 = 2457091.02863 ± 0.00047) and has a radius R
p =

1.52

−
0.11

+
0.12

R
J and mass M
p = 1.196 ± 0.072 M
J, and the eccentricity is consistent with zero. KELT-15b is another inflated Jupiter mass planet that orbits a ∼

4.6

−
0.4

+
0.5

Gyr, V = 11.2, G0 star (TYC 8146-86-1) that is near the “blue hook” stage of evolution prior to the Hertzsprung gap, and has an inferred mass

M

*

=

1.181

−
0.050

+
0.051

M
⊙ and radius

R

*

=

1.48

−
0.04

+
0.09

R
⊙, and

T

eff

 =

6003

−
52

+
56

K,

log

g

*

=

4.17

−
0.04

+
0.02

and

[

Fe

/

H

]

 = 0.05 ± 0.03. The planet orbits on a period of 3.329441 ± 0.000016 days (T
0 = 2457029.1663 ± 0.0073) and has a radius R
p =

1.443

−
0.057

+
0.11

R
J and mass M
p =

0.91

−
0.22

+
0.21

M
J and an eccentricity consistent with zero. KELT-14b has the second largest expected emission signal in the K-band for known transiting planets brighter than K < 10.5. Both KELT-14b and KELT-15b are predicted to have large enough emission signals that their secondary eclipses should be detectable using ground-based observatories.
Réflexions dialoguées autour du « rêver » chez Appelfeld dans « Le garcon qui voulait dormir »
Authors: Bindefeld Nicole , Kaganski Irène
Published: May 2016

Erwin-Aharon, adolescent, est recueilli par une organisation juive quelque part en Europe, avec d’autres rescapés, qui comme lui en « déserrance » sont regroupés dans un camp de transit avant d’être dirigés vers la Palestine, sous mandat britannique. Il commence son récit de cette errance plongé alors dans un sommeil continu de survie, dont il ne peut ni ne veut sortir. De cet espace à l’interface du sujet et de l’objet, il nous conduit à partager son asile intérieur en passant de son expérience de sommeil lourd et continuel, qui se transforme au cours de sa nouvelle vie en rêves, puis en un dialogue rêvé ininterrompu avec ses parents et ses proches. Ce processus du rêve, producteur de rêves, se met en place par une stratégie de son Moi animé d’une pulsion de vie. Il parvient ainsi, par ce jeu, à convoquer à son gré ses objets d’amour, « des objeux », perdus mais fictivement présents, et à engager avec eux un dialogue vivant. Le travail du deuil est paradoxe : le jeu annule la perte réelle des objets et maintient la relation à eux. La fonction traumatolytique du rêve (décrite par Ferenczi) va favoriser une évacuation de ses traumatismes. Toute pensée est pensée du rêve. Ce livre est pure activité de pensée (cf. Bion). « Le théâtre de la création de sens » exprimée dans les rêves va se déployer, donner sens et relation articulable vers le dehors.
Lorsque paraît le rêve : dévoilement de la dynamique du transfert
Authors: Gosse-Oudard Evelyne
Published: May 2016

Le rêve dense et riche d’une patiente présentant une pathologie lourde et peu encline à la dimension du travail psychique vient illustrer ce moment particulier de la découverte et de la prise de conscience, par les patients, du ressort transférentiel spécifique de notre approche analytique. Ce travail d’orfèvre du psychanalyste autour du rêve et de la découverte qu’il dévoile au sujet, le respect de son rythme et de ses défenses, permettront ou non à celui-ci de se saisir de l’offre analytique et infléchiront la tonalité de la relation ainsi engagée.
L’esprit du séquoia
Authors: Julliand Éric
Published: May 2016

L’auteur file la métaphore de Vieux Hibou, le vieux sage, qui installé dans le séquoïa centenaire, assiste aux tribulations avoisinantes de son espèce à plumes, et aux changements conçus par l’esprit radical des Hommes vivant « dans un siècle civilisé et scientifique ».
Le veau
Authors: Guedj Max
Published: May 2016

Du souvenir au rêve via le rêve éveillé, ou les degrés hybrides de l’hallucination : métapsychologie in-préméditée du conte.
The blissful enterprise: buddhist cultural turns in the workplace in contemporary Shanghai
Authors: Huang Weishan
Published: May 2016

En se démarquant de nombreuses recherches qui considèrent les villes de la Chine contemporaine comme des projets laïques, nationaux et capitalistes, l’article propose l’ethnographie de la présence de communautés religieuses dans des usines créées par des entrepreneurs immigrés liés par le capital à partir des années 1990. Il examine les pratiques bouddhistes sur le lieu de travail comme une nouvelle manière de comprendre les changements d’ordre moral dans la Chine contemporaine.
Innovation et territoire dans le secteur du vin au Québec
Authors: Ben Hassen Tarek , Tremblay Diane-Gabrielle
Published: May 2016

Depuis quelques années au Québec, le secteur vitivinicole est en plein développement. Cependant, ce secteur reste encore à l'étape du démarrage et fait face à plusieurs défis d'ordre climatiques et économiques, qui limitent son développement et sa compétitivité. Ce contexte est porteur d'innovations multiples. Ces innovations touchent tout à la fois les domaines technique et technologique (choix des cépages, amélioration des processus de culture et de vinification) mais aussi le domaine organisationnel et institutionnel (nouveaux modes de coordination des acteurs, nouvelles règles et normes, etc .). Nous avons étudié les différents types d'innovation qui structurent le secteur, mais également en nous fondant sur les travaux de l'école évolutionniste de l'innovation, nous avons mis en évidence le rôle des acteurs dans ces processus et la manière dont le territoire peut soutenir les activités d'innovation.
Conflits urbains, compromis et cohésion socioterritoriale : le cas de la Tohu à Montréal
Authors: Trudelle Catherine , Klein Juan-Luis , Fontan Jean-Marc , Tremblay Diane-Gabrielle , Bocquin Christophe
Published: May 2016

Le quartier Saint-Michel est marqué par une forte histoire de conflits entre ses citoyens et la Ville de Montréal au sujet des nuisances provoquées par la carrière Miron. Le dense milieu communautaire michelois et son mode de gouvernance locale sont issus de cette action collective conflictuelle qui s'est étalée sur au moins trois décennies. Malgré un contexte de mixité sociale et différentes vagues d'immigration, il y a une cohésion sociale forte dans le quartier Saint-Michel. Un sentiment d'appartenance important et des valeurs communes sont également partagés par les citoyens. Ce milieu communautaire bien structuré a non seulement permis au milieu de recevoir la Tohu 1 , partie intégrante de la Cité des arts du cirque, mais a également permis aux citoyens de s'approprier et de profiter, dans une certaine mesure, des retombées de l'implantation d'un tel équipement dans le quartier.
Socially Sustainable Suburbia: Addressing a Puzzling and Multifaceted Issue
Authors: Adelfio Marco
Published: May 2016

This issue links the concept of social sustainability with suburbia. It emphasises the multi-disciplinary, yet, insufficiently defined character of ‘socially sustainable suburbia’ and engages in a cross-disciplinary dialogue in order to overcome the remaining, predominantly negative connotation of suburban development.
ParkingPLUS: How Design Produces a Future for Long Island’s Suburban Downtowns
Authors: Williamson June , Kühl Kaja
Published: May 2016

Speculative design can be a useful tool in building broad-based support among community members and stakeholders for denser, transit-oriented development, and a greater mix of uses in North American suburbs, particularly in suburban regions characterized by both fractured governance and persistent segregation by race and class such as found in the Long Island suburbs of New York City. Urban design and in particular urban design competitions provide opportunity to initiate public conversations about the potential for retrofitting selected suburban sites to new built configurations that are more socially sustainable and resilient over time. Recent efforts by the Long Island Index, a project of the Rauch Foundation, to leverage research through sponsoring design competitions to generate an informed conversation about land use around transit stations in Long Island’s suburban downtowns serves as an example. We present the 2013-14 Build a Better Burb: ParkingPLUS design challenge and its results as well as local and national reactions to them – including debates in the freewheeling discursive space of online comments to articles. We emphasize the role that speculative design can play in advancing local policies and decision-making processes that support a greater densification and diversification of transit-supported suburban downtowns.
Sustainable Supply Chain Management
Authors: Jeble Shirish C.
Published: May 2016

In the recent years, interest in Sustainable Supply Chain Management has grown as the effects of global warming can be seen through various scientific researches. In a global economy as supply chains are spreading across continents – economic, social and environmental sustainability – commonly referred as triple bottom line (TBL) assumes significance. Focal firms in supply chain are held accountable for their economic performance by shareholders, social and environmental performance by society. Even the actions of members of their extended supply chain come under scrutiny. Growing global supply chains facilitate economic growth, improve standard of living of people and provide business opportunities to distant locations across the world. However, they have unfavorable environmental impact. In order to preserve natural resources for future generations, sustainability needs to be embedded across the supply chains. This literature review - covers different aspects of greening the supply chain. Supply chain is viewed as a system consisting of focal firm, chains of suppliers, distributors, logistics partners, retailers etc. Role of each member of supply chain in sustainability goals is discussed in detail. Extant literature has covered individual parts of supply chain, whereas this paper integrates this knowhow to facilitate learning all interrelated concepts in SSCM. Some of the supply chain companies have already taken proactive steps towards SSCM and have certified in ISO14000. Through extensive literature review, important factors which contribute for better environmental performance for an organization are studied and a model for designing and implementing SSCM strategy is presented.
Molecular Modelling, Dynamics, and Docking of Membrane Proteins
Authors: Yellapu Nanda Kumar
Published: May 2016

Computational tools and techniques are now most popular and promising to progress the research at rapid rate. Molecular modelling studies contribute their maximum role in wide variety of disciplines especially in proteomics and drug discovery strategies. Molecular dynamics and molecular docking algorithms are now became an essential part in daily research activities of every laboratory throughout the world. These strategies are now well established and standardised to study any specific protein of interest and drug molecule. But still there exist considerable drawbacks in a special concern with membrane proteins as the presently available tools and methods cannot be applied directly to them. Modelling, dynamics and docking studies of membrane proteins need a special care and attention as several challenges are to be crossed with an intensive care to produce a reliable result. This chapter is aimed to discuss such challenges and solutions to handle membrane proteins.
Technology Optimization on Preparation of Peanut Antioxidant Peptides by Bacillus Subtilis Solid State Fermentation Method
Authors: Yu Li Na , Xu Ting Ting , Zhang Chu Shu , Sun Jie , Bi Jie
Published: May 2016

The purpose of this paper is to investigate the preparation of peanut antioxidant peptides by Bacillus subtilis solid state fermentation method and to provide a theoretical basis for further investigating deep processing products of fermentation peanut meal. The preparation technics for peanut antioxidant peptides optimized with the soluble nitrogen concentration of peptides, 1, 1-diphenyl-2-picryl-hydrazyl (DPPH) and hydroxyl free radicals scavenging rates of fermentation broth as the indexes of investigation including the cell age was 20h, bacterial suspension volume was 3.0mL, fermentation temperature was 40°C, nutrient salt solution was 15mL, the fermentation time was 42h, water bath temperature was 45°C, and water bath time was 3h. The research shows that IC50 values for peptides scavenging of DPPH, hydroxyl and superoxide anion free radicals, iron and copper ion chelating rates, lipid peroxidation inhibiting rate, iron and molybdenum reducing activity were 3.48mg/mL, 6.24mg/mL, 2.06mg/mL, 0.54mg/mL, 1.19mg/mL, 4.56mg/mL, 9.58mg/mL and 2.17mg/mL, respectively.
Comparative Study of the Corrosion Behavior of Low-Nickel AISI 202 and Conventional AISI 304 Stainless Steels in Citric Acid Using Electrochemical Techniques
Authors: Mulimbayan Francis , Mena Manolo G.
Published: May 2016

Stainless steel (SS) is one of the most commonly used metallic food contact materials. It may be classified based on its microstructure whether ferritic, austenitic, martensitic, duplex or precipitation hardened. Austenitic SS, among mentioned grades, has the largest contribution to market due to its numerous industrial and domestic applications. In this study, the corrosion behavior of AISI 202 SS – a cheaper grade of stainless steel, in three different solution temperatures of citric acid was investigated using different electrochemical techniques such as open-circuit potential (OCP) measurements, potentiodynamic polarization and electrochemical impedance spectroscopy (EIS). The results were compared to that obtained from conventional AISI 304 SS. OCP, polarization and impedance measurements agreed that AISI 202 SS has comparable resistance to that of AISI 304 SS in citric acid at ambient temperature and at 50 °C. At 70 °C, results of OCP measurements suggest that AISI 304 SS exhibited greater performance as indicated by more positive OCP values in the designated solution. EIS results indicate that the two alloys have identical corrosion resistance even at 70 °C as indicated by their comparable polarization resistance (Rp). The corrosion mechanism in both alloys is charge-transfer controlled as indicated by depressed semi-circular appearance of the generated Nyquist plots. The values of corrosion current densities (icorr) extracted from polarization curves indicate that the initial corrosion rates were higher in AISI 304 than AISI 202 SS suggesting that formation of more protective film may have occurred on the former alloy.
Plugging Agent of Shale Base on Nano Flexible Polymer
Authors: An Yu Xiu , Jiang Guan Cheng , Qi You Rong , Ge Qing Ying
Published: May 2016

In this paper, the nano flexible polymer was synthesized and the plugging property of the polymer in the drilling fluid was studied. The characterization and properties of nano flexible polymer were invested by Particle Size Analyzer and Transmission Electron Microscopy. The nano flexible polymer was synthesized successfully and it was flexible nano material both in water and in drilling fluid. The filtration ability of the polymer was studied by drilling fluid filter press and the results indicated that the filtration property was equal to commonly used fluid loss agent in drilling fluid. The plugging ability was studied by specific surface and porosity physical adsorption instrument (BET). The surface area reduced after treated with the polymer, indicating the nano flexible polymer entered into nanopores of shale formation due to the adsorption in the surface of shale. It was further exhibited that nanopores of shale were plugged by the nano flexible polymer.