bluuebunny/crossref_metadata_2025 huggingface dataset:
On the path towards universal coverage of hepatitis C treatment among people receiving opioid agonist therapy (OAT) in Norway: a prospective cohort study from 2013 to 2017
Authors: Aas Christer , Vold Jørn Henrik , Skurtveit Svetlana , Odsbu Ingvild , Chalabianloo Fatemeh , Økland Jan-Magnus , Leiva Alexander , Vickerman Peter , Johansson Kjell Arne , Fadnes Lars Thore
Published: August 2019

Background

The development of new direct-acting antiviral (DAA) medications together with opioid agonist therapy (OAT) have been put forward as having an important role in the management and elimination of chronic hepatitis C (HCV) infection. Yet, HCV treatment uptake and coverage have remained low among OAT populations. We aimed to calculate cumulative HCV treatment coverage among individuals enrolled in OAT in Norway between 2013 and 2017, and to document the treatment transition to interferon-free regimens. Moreover, we aimed to describe adherence to DAAs in the same cohort.

Methods

This observational study was based on data from The Norwegian Prescription Database (NorPD). We studied dispensed OAT and HCV treatment annually to calculate the cumulative frequency, and employed secondary sources to further calculate prevalence, incidence and HCV treatment coverage from 2013 to 2017, among the OAT population. Factors associated with adherence to DAAs were identified a priori and subject to logistic regression.

Results

10,371 individuals were identified with dispensed OAT, 1,475 individuals of these with dispensed HCV treatment. Annual HCV treatment coverage increased from 3.5% (95% CI: 3.2-4.4) in 2013 to 17% (95% CI: 17-20) in 2017, giving a cumulative HCV coverage among OAT patients in Norway of 38.5%. A complete shift to interferon-free treatment regimens occured, where DAAs accounting for 32% of HCV treatments in 2013 and 99% in 2017. About two-thirds of OAT patients were considered adherent to their DAA regimens across all genotypes. High-level of OAT continuity was associated with improved adherence to DAAs (aOR 1.4, 95% CI: 1-2, p=0.035).

Conclusions

A large increase in HCV treatment coverage attributed by a complete shift to interferon-free regimens among the Norwegian OAT population has been demonstrated. However, a further substantial scale-up in HCV treatment is required to reach the universal targets of controlling and eradicating the HCV endemic.
Epidemiology and comorbidities of patients with rheumatoid arthritis in Spain during the period 2002-2017
Authors: Del-Moral-Luque Juan Antonio , Gil-Conesa Mario , Gil-Prieto Ruth , Gil-de-Miguel Ángel , Mazzuccheli-Esteban Ramón , Caravaca Gil Rodriguez
Published: August 2019

Background: Rheumatoid arthritis (RA) is a chronic autoimmune rheumatic disease that is associated with multiple comorbidities and has a significant economic impact on the Spanish health system. The objective of this study was to estimate the hospital burden of rheumatoid arthritis, its variants and their associated comorbidities.

Methods: Observational descriptive study that reviewed hospital records from the CMBD. We included all hospitalizations of patients in Spain whose main diagnosis or comorbidity in the ICD-9-CM was rheumatoid arthritis during the period of 2002-2017.

Results: A total of 315,190 hospitalizations with the RA code were recorded; 67.3% were in women. The mean age of the patients was 68.5 ± 13.9 years. The median length of hospital stay was 7 days (IQR 3-11 days). In 29,809 of the admissions, RA was coded as the main diagnosis (9.4%). When RA was not coded as the main diagnosis, the most frequent main diagnoses were diseases of the circulatory system (18.9%) and diseases of the respiratory system (17.4%). The hospitalization rate during the period of 2002-2017 was 43.8 (95% CI: 43.7-44.0) per 100,000 inhabitants. The total cost for the healthcare system was 1.476 million euros, with a median of 3,542 euros per hospitalization (IQR 2,646-5,222 euros).

Conclusions: In Spain, the highest hospitalization rates for RA were registered within the continental climate region. The hospitalization rate of patients with RA increased during the study period, despite the decrease in the hospitalization rate when RA was the main diagnosis.
Quantitative analysis of Polydatin in a Turkish oak: Quercus coccifera L. with HPLC-DAD
Authors: YÜZBAŞIOĞLU BARAN Merve , ŞÖHRETOĞLU Didem , KURUÜZÜM UZ Ayşe
Published: August 2019

In this study, a new, simple, rapid and sensitive HPLC-DAD method was used for analysing polydatin contents of Quercus coccifera (Fagaceae) woody parts extracted with methanol and water. Our results showed that methanol and water extracts of Q. coccifera had high polydatin contents: 14.898±0.147 and 5.574±0.112 mg/g dry extracts, respectively. This is the first developed analytical method for qualitative and quantitative analysis of polydatin in Quercus L. species.
Socio-Economic Benefit of Lake Ecosystem (In Case of Lake Ziway)
Authors: Gebremedhin Gezahegne Seyoum , Belliethathan Satishkumer
Published: August 2019

This study focused on the socio-economic benefit of the Western shoreline of Lake Ziway ecosystem.  Lake Ziway great importance for food and water for both groups of respondents and additional sources of raw material, energy, cultivation, organic fertilizers, genetic and medicinal plants. Lake Ziway also has a major economic benefit for both groups of respondents. The respondent fishermen caught a mean amount of 2,524Kg per year with a minimum and maximum amount of fish 504Kg and 16,800Kg per year respectively and with this fish-catching, they got an average income of 51,398 Birr ($2,570) per year with range of 7,200 Birr ($360) and 288,000 Birr ($14,400) per year. As like of fishermen small scale irrigation also got economic benefit with their production of cereal crops, fruits, and vegetables. They produce in average 13.47Quintal of cereal crop and 69.56Quintal of fruits and vegetables per year and they got an average income of 7,727 Birr ($386) and with a range of 13,714 Birr ($686) per year respectively. this incurred that wetland ecosystem has a lot of socio-economic benefit for the people live nearby especially for developing countries like Ethiopia they are more dependent on a natural ecosystem like of Lake Ziway.
The Rationale of Continuous Assessment for Development of Competencies in Tanzania Secondary Schools
Authors: Mkimbili Selina , Kitta Septimi Kitta Reuben
Published: August 2019

This paper attempts to illuminate the rationale of continuous assessment for competence development in secondary schools in Tanzania. Although, the curriculum for secondary schools in Tanzania has changed from content-based to competency-based, most teachers in secondary schools are still practicing traditional pen-and-pencil continuous assessment which is far from developing competence in students. There is a dire need for revising the assessment procedures, particularly continuous assessment to ensure the attainment of better competence level among students and realisation of high quality education in Tanzania. This paper examines the rationale of continuous assessment for competence development, as well as the challenges of implementing it. This paper recommends capacity building for secondary school teachers on competence-based assessment, so as to enable them to engage in authentic continuous assessment.
René Girarda teoria mimetyczna. Między religią a polityką
Authors: Romejko Adam
Published: August 2019

W świecie zachodnim popularne jest przekonanie, że sfera polityczna i religijna (państwowa i kościelna) są niezależne (por. Mt 22,21). Uczonym, który uważał, że u początków ludzkiej kultury (cywilizacji) było inaczej, jest francuski antropolog i literaturoznawca René Girard. Podkreśla on, że religia (rytuał ofiarniczy) stoi u podstaw ludzkich instytucji, w tym tych o politycznym charakterze. W wypracowanej teorii, określanej mianem mimetycznej, zwraca uwagę na przemoc, która w kolektywnej formie jest w stanie budować i podtrzymywać egzystencję ludzkiej wspólnoty. W teorii mimetycznej pojawiają się cztery kwestie korespondujące z polityką: 1) budowanie politycznej wspólnoty na podstawie niechęci do innych (jednostki, grupy mniejszościowej); 2) wykorzystanie ludzkiego mimetyzmu w kierowaniu grupami społecznymi; 3) pozycjonowanie siebie jako ofiary, które ma na celu zyski polityczne itp.; 4) nowoczesna troska o ofiary, stanowiąca oręż wobec politycznych przeciwników. Teorię mimetyczną można stosować w  badaniach politycznych fenomenów. W  niniejszym artykule zanalizowano za pomocą „Girardowskich okularów” niemiecki talk-show maybrit illner z dn. 2 listopada 2017 r
Expression of Thanatin in HEK293 Cells and Investigation of its Antibacterial Effects on Some Human Pathogens
Authors: Tanhaeian Abbas , Azghandi Marjan , Mousavi Zahra , Javadmanesh Ali
Published: August 2019

Background:

Thanatin is the smallest member of Beta-hairpin class of cationic peptide derived from insects with vast activities against various pathogens.

Objective:

n this study, the antimicrobial activity of this peptide against some species of human bacterial pathogens as well as its toxicity on NIH cells were evaluated.

Method:

Thanatin DNA sequence was cloned into pcDNA3.1+ vector and transformed into a DH5α bacterial strain. Then the recombinant plasmids were transfected into HEK-293 cells by calcium phosphate co-precipitation. After applying antibiotic treatment, the supernatant medium containing thanatin was collected. The peptide quantity was estimated by SDS-PAGE and GelQuant software. The antimicrobial activity of this peptide was performed with Minimum Inhibitory Concentration (MIC) method. In addition, its toxicity on NIH cells were evaluated by MTT assay.

Results:

The peptide quantity was estimated approximately 164.21 µmolL-1. The antibacterial activity of thanatin was estimated between 0.99 and 31.58 µmolL-1 using MIC method. The result of cytotoxicity test on NIH cell line showed that the peptide toxicity up to the concentration of 394.10 µmolL-1 and for 48 hours, was not statistically significant from negative control cells (P>0.05). The antimicrobial assay demonstrated that thanatin had an antibacterial effect on some tested microorganisms. The results obtained in this study also showed that thanatin had no toxicity on mammalian cell lines including HEK293 and NIH.

Conclusion:

Antimicrobial peptides such as thanatin are considered to be appropriate alternatives to conventional antibiotics in treating various human pathological diseases bacteria.
Lanthanum, Gallium and their Impact on Oxidative Stress
Authors: Todorov Lozan , Kostova Irena , Traykova Maria
Published: August 2019

The role metals play in living organisms is well established and subject to extensive research. Some of them participate in electron-exchange reactions. Such reactions cause generation of free radicals that can adversely impact biological systems, as a result of oxidative stress. The impact of ‘non-biological’ metals on oxidative stress is also a worthy pursuit due to the crucial role they play in modern civilization. Lanthanides (Ln) are widely used in modern technology. As a result, human exposure to them is increasing. They have a number of established medical applications and are being extensively researched for their potential antiviral, anticancer and anti-inflammatory properties. The present review focuses on lanthanum (La) and its impact on oxidative stress. Another metal, widely used in modern high-tech is gallium (Ga). In some respects, it shows certain similarities to La, therefore it is a subject of the present review as well. Both metals exhibit ionic mimicry which allows them to specifically target malignant cells, initiating apoptosis that makes their simple salts and coordination complexes promising candidates for future anticancer agents.
Molecular Insights into the Mechanisms Underlying the Cholesterol- Lowering Effects of Phytosterols
Authors: Cedó Lídia , Farràs Marta , Lee-Rueckert Miriam , Escolà-Gil Joan Carles
Published: August 2019

Dietary phytosterols, which comprise plant sterols and stanols, reduce plasma Low-Density Lipoprotein-Cholesterol (LDL-C) levels when given 2 g/day. Since this dose has not been reported to cause health-related side effects in long-term human studies, food products containing these plant compounds are used as potential therapeutic dietary options to reduce LDL-C and cardiovascular disease risk. Several mechanisms have been proposed to explain the cholesterol-lowering action of phytosterols. They may compete with dietary and biliary cholesterol for micellar solubilization in the intestinal lumen, impairing intestinal cholesterol absorption. Recent evidence indicates that phytosterols may also regulate other pathways. Impaired intestinal cholesterol absorption is usually associated with reduced cholesterol transport to the liver, which may reduce the incorporation of cholesterol into Very-Low- Density Lipoprotein (VLDL) particles, thereby lowering the rate of VLDL assembly and secretion. Impaired liver VLDL production may reduce the rate of LDL production. On the other hand, significant evidence supports a role for plant sterols in the Transintestinal Cholesterol Excretion (TICE) pathway, although the exact mechanisms by which they promote the flow of cholesterol from the blood to enterocytes and the intestinal lumen remains unknown. Dietary phytosterols may also alter the conversion of bile acids into secondary bile acids, and may lower the bile acid hydrophobic/hydrophilic ratio, thereby reducing intestinal cholesterol absorption. This article reviews the progress to date in research on the molecular mechanisms underlying the cholesterol-lowering effects of phytosterols.
Available Software for Meta-Analyses of Genome-Wide Expression Studies
Authors: Forero Diego A.
Published: August 2019

Advances in transcriptomic methods have led to a large number of published Genome-
Wide Expression Studies (GWES), in humans and model organisms. For several years, GWES involved
the use of microarray platforms to compare genome-expression data for two or more groups of
samples of interest. Meta-analysis of GWES is a powerful approach for the identification of differentially
expressed genes in biological topics or diseases of interest, combining information from multiple
primary studies. In this article, the main features of available software for carrying out meta-analysis
of GWES have been reviewed and seven packages from the Bioconductor platform and five packages
from the CRAN platform have been described. In addition, nine previously described programs and
four online programs are reviewed. Finally, advantages and disadvantages of these available programs
and proposed key points for future developments have been discussed.
Genes Expression Classification Through Histone Modification Using Temporal Neural Network
Authors: Nair Rajit , Bhagat Amit
Published: August 2019

Background:

Genes expression is high dimensional data, so it is very difficult to classify
high dimensional data through traditional machine learning approaches. In this work we have proposed
a model based on combined approach of Convolutional Neural Network and Recurrent Neural
Network, both belong to deep learning model. The prediction has shown improved result than other
machine learning algorithms. Expressions are generated through histone modification.

Methods:

To improve the accuracy deep learning model is proposed i.e. based on Convolutional and
Recurrent neural network. This proposed model uses filter, causal convolutional layers and Residual
Block for predictions.

Results:

In this work we have implemented the machine learning algorithms and deep learning algorithms
like Logistic Regression, SVM, CNN, Deep Chrome and the proposed Temporal Neural
Network. The performance is measured on the basis of parameters like accuracy, precision and AUC
on the training and testing set.

Conclusion:

The proposed Temporal Neural Network model has shown better performance than
other machine learning and deep learning algorithms. Due to this proposed deep learning algorithm
can be successfully applied on the genes expression dataset.
Social Work With Families: “First Session”
Authors: KARAHAN Gül , DUYAN Veli
Published: August 2019

Social work with

families is a type of service that is provided to families in order to support their

problems. The nature of social work offers a perspective that usually

structures the focus of the intervention process as a family. To address the

problem at the family level and to see the family members together, it is

possible to see and evaluate the problem from the perspective of all members of

the family. Social work intervention with families, who have a direct impact on

the scope and depth of the assessment process, presents a number of advantages

that require in-depth knowledge and skills at every stage of the intervention

process, as well as many advantages for social workers to implement effective

practices.Social work with

families is a professional help service, which requires competence at every

stage. This study, in which the first session of social work at the family

level is handled with a theoretical approach, is structured to provide a

framework for the competent implementation of the first session of social work

intervention with the families and the components constituting the requirements

of the first session are discussed on the basis of a holistic and relational

perspective. Ailelerle

sosyal hizmet, ailelere sorunlarının çözümünde destek olmak üzere sunulan bir

hizmet türüdür. Sosyal hizmetin doğası, müdahale sürecinin odağını genellikle

aile olarak yapılandıran bir perspektif sunar. Sorunu aile düzleminde ele almak

ve aile üyelerini bir arada görmek, sorunu ailenin tüm üyelerinin bakış açısından

görüp değerlendirebilmeye olanak verir. Değerlendirme sürecinin kapsamı ve

derinliği üzerinde doğrudan etkiye sahip olan ailelerle sosyal hizmet

müdahalesi, müdahale sürecinin her basamağında derinlemesine bilgi ve beceri

gerektiren çeşitli zorluklar içermesinin yanı sıra, sosyal hizmet uzmanlarına

etkili uygulamalar yapabilmeleri için pek çok avantaj sağlar.

Ailelerle

sosyal hizmet, her aşaması yetkinlik gerektiren, profesyonel bir yardım

hizmetidir. Sosyal hizmetin aile düzeyindeki uygulamalarının ilk oturumunun

kuramsal bir yaklaşımla ele alındığı bu çalışma, ailelerle sosyal hizmet

müdahalesinin ilk oturumunun yetkin uygulamasına ilişkin bir çerçeve oluşturmak

üzere yapılandırılmış ve ilk oturumun gerekliliklerini oluşturan bileşenler,

bütünsel ve ilişkisel bir bakış temelinde ele alınmıştır.
Lazos caribeños en Holguín, Cuba
Authors: Valcárcel Rojas Roberto , Pérez Iglesias Lourdes del Rosario , Guarch Rodríguez Elena
Published: August 2019

No precisa de resumen.
Tratamiento de las complicaciones motoras en la enfermedad de Parkinson
Authors: Moreno López Claudia Lucia , Cerquera Cleves Sonia Catalina
Published: August 2019

Las fluctuaciones motoras y las discinesias hacen parte de las complicaciones motoras que invariablemente se presentarán con la progresión y avance de la enfermedad de Parkinson. Se estima que el 90 % de los pacientes las padecen después de 10 años de enfermedad. El tratamiento de estas condiciones requiere entender el patrón, las características y el tipo de fluctuaciones o discinesias de cada paciente. En este capítulo se realiza una revisión detallada sobre cada una de estas complicaciones motoras y se muestran los algoritmos para su abordaje y manejo, incluyendo las indicaciones y recomendaciones de las terapias avanzadas disponibles en Colombia, como la cirugía de estimulación cerebral profunda y la apomorfina subcutánea.
Trastorno de control de impulsos (TCI) en enfermedad de Parkinson
Authors: Arango Uribe Gabriel José , Bernal Pacheco Oscar
Published: August 2019

Los trastornos del control de impulsos (TCI) son complicaciones psiquiátricas de la enfermedad de Parkinson (EP), cada vez más reconocidos, pero que persisten subdiagnosticados y pueden llegar a ser muy disruptivos para la vida familiar del paciente, en especial si no son detectados a tiempo. Si bien uno de sus principales riesgos es el uso de agonistas dopaminérgicos, estos no son su única causa, se pueden ver sin relación con medicamentos o con cualquier tratamiento para la EP. Por lo tanto, se debe interrogar sistemáticamente por su presencia y educar al paciente y su familia para que sean reportados en cualquier momento. El objetivo de este capítulo es describir los diferentes tipos de TCI, sus factores de riesgo y tratamiento.
Espectro clínico y tratamiento del trastorno cognoscitivo y demencia asociada a la enfermedad de Parkinson
Authors: Muñoz Ospina Beatriz Elena , Orozco Vélez Jorge Luis
Published: August 2019

La prevalencia del deterioro cognitivo mínimo en pacientes con EP está en un rango de 20-50 %. La prevalen-cia puntual de la demencia asociada a la enfermedad se estima en alrededor del 25-30 °% con un incremento proporcional en relación con la edad y el tiempo de evolución de la enfermedad. El perfil clínico puede ser heterogéneo y hace referencia a la alteración en los diferentes dominios que supone un substrato neurobiológico diferente. La disfunción ejecutiva suele ser más frecuente en etapas tempranas de la enfermedad, aunque también hay perfiles clínicos corticales. Hay síntomas neuropsiquiátricos como la depresión, la ansiedad y el discontrol de impulsos que pueden afectar la cognición. La valoración rutinaria de las actividades de la vida diaria y el desempeño funcional se ha relacionado con el grado de compromiso así como con el rendimiento cognitivo global. Pacientes en estadios avanzados y candidatos a la cirugía de estimulación cerebral profunda requieren la evaluación neuropsicológica para seguimiento e identificación de potenciales riesgos o contraindicaciones cognitivas, comportamentales y/o emocionales. Las conclusiones del consenso de cognición son: 1) el deterioro cognitivo mínimo es común en los pacientes, incluso en estadios tempranos; 2) el perfil clínico es heterogéneo, aunque la disfunción ejecutiva es más frecuente; 3) la valoración inicial permite detectar perfiles de riesgo a demencia; 4) deben usarse instrumentos validados para esta población; 5) los síntomas neuropsiquiátricos pueden afectar el desempeño del paciente, y 6) la valoración de la independencia funcional permite explorar el impacto de la cognición en la cotidianidad.
Psicosis en enfermedad de Parkinson
Authors: García Orjuela Xiomara
Published: August 2019

La psicosis en enfermedad de Parkinson es una entidad recientemente descrita cuya importancia radica en su alta morbilidad y mal pronóstico asociados. Su diagnóstico y manejo representan un reto clínico cotidiano. Sin embargo, el conocimiento de su definición y criterios diagnósticos, el uso de determinadas escalas de severidad y seguimiento y el ejercicio terapéutico riguroso permitirán al clínico abordar en forma sistemática y exitosa este tipo de paciente.
La (re)producción de las élites en tiempos de democratización del sistema universitario. Análisis conceptual a partir de las experiencias latinoamericanas
Authors: Quaresma María Luisa , Villalobos Dintrans Cristóbal
Published: August 2019

El artículo desarrolla un análisis teórico-conceptual sobre el rol del sistema universitario en los procesos de movilidad y reproducción de la élite en el contexto de la democratización escolar. Se presenta una revisión de los principales debates sobre el concepto de élite y se analiza la relación entre (re)producción de la élite y universidad/carrera en países desarrollados y América Latina, con énfasis en dos países cuyos sistemas universitarios se caracterizan por sus altos niveles de democratización escolar y segregación interna: Chile y Brasil. Así, se propone una reflexión que muestra la importancia de la confluencia entre universidad y carrera en la configuración de los procesos de movilidad y reproducción social, entendiendo la configuración de la élite como un proceso dinámico y adaptativo.
O ESTAR EM CENA COMO UM EXISTIR POÉTICO
Authors: Machado Celeia
Published: August 2019

O percurso de criação do ator requer um estado cênico de constante mobilidade e invenção de formas de estar no mundo. É no seu corpo que o ator agencia o seu fazer artístico, na busca de colocar um outro no lugar de si. Em cena, faz surgir a máscara, estabelecendo um jogo de presença da não-presença e, sobretudo, tornando-se capaz de fazer surgir um estado de flutuabilidade e mobilidade, no qual é possível, em seu próprio corpo, transitar múltiplas possibilidades de estar no mundo. Assim, tomo como propósito pensar a condição ontológica que atravessa o ato de criação do ator, refletindo sobre a forma poética de a criação teatral dialogar com a experiência humana de tornar-se e de vir a “ser quem se é”.
ALTERNATIVAS METODOLÓGICAS DA INVESTIGAÇÃO ACADÊMICA SOBRE PROCESSOS COLETIVOS EM DANÇA: O CASO DE UMA PESQUISA-AÇÃO EM ESCOLAS DE VIÇOSA, MG
Authors: Vieira Alba Pedreira
Published: August 2019

O objetivo foi avaliar o impacto de projetos de pesquisa-ação de dança no saber estético e apreciativo de alunos do ensino básico. O trabalho de campo aconteceu em Viçosa, Minas Gerais, aonde atendeu-se dez turmas de oito escolas públicas de ensino básico por um ano e meio; cada escola foi atendida por cinco meses. Os participantes tiveram uma ou duas aulas teórico-práticas semanais de gêneros diversificados de dança, fruição de vídeos, e assistiram apresentações e espetáculos ao vivo, de grupos e/ou artistas locais e nacionais, de diversos estilos, na escola, teatros e na sede do Curso de Graduação Dança da Universidade Federal de Viçosa/UFV. Eles também observaram aulas práticas do Curso de Dança da UFV, bem como aulas de dança para adultos de projetos de extensão desta universidade. Vários participantes se envolveram com processos de criação coreográfica e apresentaram-se como bailarinos em diferentes apresentações na própria escola, em quatro espetáculos nos teatros da UFV, uma apresentação em praça pública e um espetáculo itinerante em quatro instituições de educação infantil. Os participantes responderam a dois questionários (inicial e final); seus dados também foram coletados através de observação participante. Os resultados obtidos a partir de análise dos dados dos participantes indicaram melhoria significativa do conhecimento artístico dos participantes: 73% consideraram que as atividades do projeto mudaram sua visão do que é dança e 65% acharam que as atividades do projeto mudaram sua visão do que é uma apresentação de dança. Concluímos que o trabalho permitiu aos envolvidos um enriquecimento cultural e ao mesmo tempo uma valorização do patrimônio cultural imaterial e histórico da região, do país e do exterior. Sugerimos que, através de metodologias educacionais diversificadas e duradouras de fruição e usufruição, pode-se ampliar a sensibilização estética para o apreciar artístico e estético em dança.
A FORMAÇÃO DO ATOR NA ESCOLA DO ATOR CÔMICO
Authors: Scheffler Ismael
Published: August 2019

O artigo traça um breve panorama sobre as escolas de formação de ator na cidade de Curitiba, PR, desde a Escola de Arte Dramática do SESI, criada no final dos anos 50, até o surgimento das primieras escolas e cursos independentes, em meados dos anos 90. Após, apresenta aspectos da história da Escola do Ator Cômico, destacando a trajetória de formação de Mauro Zanatta e os primeiros anos de trabalho. A seguir, o artigo apresenta o Curso de Comédia para Atores e Não-atores, seu funcionamento e propostas pedagógicas, incluindo ao final, a transcrição de parte da entrevista concedida para a realização deste estudo, evidenciando conceitos teatrais que determinam a prática pedagógica de Zanatta junto à Escola.
FRAGMENTOS DE UM TEATRO AMOROSO
Authors: Gil João Pedro Alcantara
Published: August 2019

O trabalho apresenta como temática o teatro em suas múltiplas linguagens, observado através do olhar afetuoso do autor em seus mais de 30 anos de carreiras artística e docente. Trata-se de uma reunião de artigos jornalísticos revistos, ampliados e ilustrados. O autor convida os leitores a discutirem o fazer teatral contemporâneo, com base nas suas experiências de encenador e espectador, na expectativa de promover um amadurecimento crítico dos sujeitos envolvidos nos processos artísticos e pedagógicos com teatro.
O TEATRO DO MUNDO COMO ASSEMBLEIA CONGELADA – A PROVA DE FOGO DE MAIO DE 1968 NO BRASIL
Authors: Delmanto Ivan
Published: August 2019

O artigo analisa uma peça de Consuelo de Castro, A Prova de fogo, e procura revelar, nas modificações realizadas a partir dos modelos originais do drama moderno e do teatro épico europeus, que a obra pode ser melhor compreendida a partir das tensões entre regime militar brasileiro e movimento estudantil, deflagradas durante o ano de 1968.
O ÚLTIMO CARRO: UMA VIAGEM DE TREM COM JOÃO DAS NEVES NOS ANOS 1960/70
Authors: Paranhos Kátia
Published: August 2019

Por vezes condenada como escapista, outras vezes incensada como ferramenta de libertação revolucionária, a arte, de modo geral, continua sendo um tema candente tanto na academia como fora dela. Este trabalho aborda as múltiplas faces de João das Neves, autor de O último carro, espetáculo que deveria ser apresentado pelo Grupo Opinião em 1968 e só encontrou lugar e tempo propício para sua encenaçãoem 1976. O eixo de análise aqui proposto consiste, de certa forma, em tentar iluminar diferentes maneiras de se fazer teatro no Brasil, no caso, pelas bordas. Afinal, o diretor, recentemente falecido, se notabilizou pelo engajamento político ou “legítimo”, como lembra Eric Hobsbawm noutro contexto, dando vazão à capacidade de lançar ideias e desafios, em plena ditadura militar, propondo então indagações que ecoam até os dias de hoje.
BELTING PÓS RENT: UM ESTUDO SOBRE A EVOLUÇÃO DO CANTO DO TEATRO MUSICAL NORTE-AMERICANO
Authors: Oissa Adrielly
Published: August 2019

Observando os relatos sobre a tragédia vocal que aconteceu no musical Rent de 1996, quando grande parte do elenco perdeu a voz, e com base nos estudos de Schutte e Miller (1992), Popeil (1999), Edwin (2007), Durham-Lozaw (2014) e Silva (2016) sobre a voz do belt, a autora propõe uma reflexão a respeito do ensino do canto do teatro musical norte-americano e as transformações sofridas na pedagogia vocal do belt ao longo dos anos. Para tal, foram analisadas duas interpretações de uma mesma canção do musical Rent, executadas pela mesma cantora em um intervalo de 10 anos, uma em 1996 e outra em 2006. Os resultados desse estudo mostram que houve significativa mudança na pedagogia vocal do canto de teatro musical norte-americano, o que proporciona aos cantores de teatro musical contemporâneo, menor risco de sofrerem com problemas vocais causados pelo uso inadequado da voz. Além disso, mostram a importância de que professores de canto e especialistas em voz cantada conheçam a fisiologia vocal na produção do belting e saibam como executar e aplicar a técnica aos seus alunos.
TRÊS PARADIGMAS PARA A CENOGRAFIA: Instrumentos para a cena contemporânea
Authors: Machado João Carlos
Published: August 2019

Procurando analisar os instrumentais disponíveis para a cenografia na contemporaneidade, e observando momentos da história da encenação teatral, o texto apresenta três paradigmas principais: a abordagem da arte como representação mimética, a abordagem da arte como linguagem e a abordagem da arte voltada para o processo de percepção do espectador.
O TEATRO DE BRECHT EM DOIS GESTUS DE HELENE WEIGEL
Authors: De Oliveira Ana Paula Pedroso
Published: August 2019

Brecht acreditava na mudança. Para ele fatal era não aprender. Na busca por seu teatro, em todos os aspectos, foi um experimentador. No caso de “Mãe Coragem e seus filhos”, os modelos revelam o quanto os gestus de Helene Weigel demonstram a atitude crítica da atriz, e, ao mesmo tempo, aalienação a que está submetida sua personagem. Este artigo traz um breve resumo do teatro de Brecht e do gestus em quanto revelador.
PROFESSOR PRESENTE: A PRODUÇÃO DE CONHECIMENTO EM TEATRO NUM ESPAÇO-TEMPO DE TRANSIÇÃO
Authors: Dos Santos Vera Lúcia Bertoni
Published: August 2019

Neste texto discute-se o saber científico na contemporaneidade a partir das idéias de Boaventura de Sousa Santos acerca da chamada "nova ordem científica emergente". Considerando-se o ensino na perspectiva da produção do conhecimento e o trabalho docente relacionado à postura investigativa, ou ao princípio da indissociabilidade entre ensino e pesquisa, busca-se evidenciar a necessidade de uma ruptura de cunho epistemológico nos processo de ensino-aprendizagem em teatro na universidade.
O CORPO NA COMPOSIÇÃO DO DRAMA
Authors: Falkembach Maria
Published: August 2019

O presente artigo elabora uma reflexão sobre a arte do ator-dançarino na composição da dramaturgia do corpo. Entende que a criação do ator-dançarino se dá no desenvolvimento do seu projeto poético, no seu processo cognitivo, por vias do pensamento criativo sobre a materialidade do corpo. Desenvolve e contextualiza o conceito de dramaturgia do corpo como criação de conhecimento na articulação estética para a configuração de ações, na arquitetura viva do corpo cênico.
Optimization of reflux extraction for cat’s whiskers leaves extract using response surface methodology
Authors: Ariff Mohd , Abdullah Norfazilah
Published: August 2019

Cat?s whiskers (Orthosiphon stamineus) is a medicinal plant which comprises several dynamic pharmacological properties such as anti-inflammatory, antioxidant and antibacterial. In small and medium-scale industries, conventional reflux extraction method is favored as compared to other non-conventional extraction methods due to cost effectiveness and simple operating procedures. In this study, response surface methodology (RSM) was applied to optimize the reflux conditions for extraction of cat?s whiskers leaves in order to achieve a high content of antioxidant activity in the extracts. Central composite experimental design (CCD) with three factors and three levels was employed to consider the effects of the operation conditions. Antioxidant activity of the extracts were based on free radical scavenging activity (DPPH assay) and were analyzed using a UV-Vis spectrophotometer. Based on RSM, the antioxidant activity could be maximized when the operation conditions were 125 ?m for particle size, 1.5:20 for sample-to-solvent ratio, and 2 h for extraction time. Under these optimal conditions, the predicted value of the antioxidant activity was compared with the actual, and the mean error was 0.46%. This indicates the suitability of the model for optimizing the conditions for the reflux extraction of cat?s whiskers leaves.
THE COPING STRATEGY OF THE SEAWEED FARMING WORKERS IN RANDUSANGA VILLAGE, BREBES
Authors: Arina Harmashinta Wahyu , Sasongko Gatot , Wahyudi Yustinus
Published: August 2019

The seaweed farming workers at Randusanga Wetan and Kulon village were facing a problem which also affecting their welfare, mainly their income. They could not decide their exact income because of their employment status, production and price instability. Coping strategy, which had been implemented, was one way to solve their problem as it made a connection and an active strategy. The form of ‘connection’ negotiated the portion of profit-sharing and enabled a household to borrow some money. Then, the active strategy was implemented by wild crab fishing, involving family member, intercropping with fish, working for 2-3 farmers, and utilizing ‘sumpil’. This way, they could achieve a good welfare while at the same time, kept producing for their income.
Sobre Elena Díaz Silva, Aribert Reimann y Randal Sheppard (eds.), Horizontes del exilio. Nuevas aproximaciones a la experiencia de los exilios entre Europa y América Latina durante el siglo XX
Authors: Morales Muñoz Daniela
Published: August 2019

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Sobre Gabriel Entin (ed.), Rousseau en Iberoamérica. Lecturas e interpretación entre monarquía y revolución
Authors: Palti Elías José
Published: August 2019

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Sobre Elías Pino Iturrieta (coord.), Historia mínima de Venezuela
Authors: López Portillo Felicitas
Published: August 2019

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Sobre Zeb Tortorici, Sins Against Nature. Sex & Archives in Colonial New Spain
Authors: Saldarriaga Gregorio
Published: August 2019

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Sobre Haydeé López Hernández, En busca del alma nacional. La arqueología y la construcción del origen de la historia nacional en México
Authors: Vázquez León Luis
Published: August 2019

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Sobre Nayelli Castro Ramírez (coord.), Traducción, identidad y nacionalismo en Latinoamérica
Authors: Ramos García Andrés
Published: August 2019

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China en el discurso económico de América Latina
Authors: Mosquera Mariano
Published: August 2019

El creciente protagonismo económico de China en América Latina y los actuales debates sobre la influencia negativa o positiva de China en la región contextualizan la investigación. El objetivo es describir la presencia y la orientación de China en el discurso económico de la publicación Panorama de la Inserción Internacional de América Latina y el Caribe de la Comisión Económica Para América Latina (CEPAL). La investigación alcanzó dos conclusiones. Primero, la presencia de China no crece de manera uniforme en el tiempo. Segundo, los encuadres de problemas y amenazas de China para con la región predominan en el período 1998-2001. A partir del año 2002 los encuadres se centran en oportunidades.
As ações desencontradas da política ex- terna do Brasil frente à Argentina (1951- 1954)
Authors: Setti Reckziegel Ana Luiza
Published: August 2019

O artigo aborda as ações dos agentes estatais brasileiros no que se refere às relações com Argentina, durante os governos de Getúlio Vargas (1951-1954) e Juan Domingo Perón (1950-1955). As duas abordagens disputaram a primazia na definição do viés da política externa: a presidencial, que encaminhava a aproximação com a vizinha Argentina, e a do Ministério das Relações Exteriores, permeada por tensões e divergências no nível intra diplomático. Para a compreensão desse cenário, uma variável de análise importante foi a política interna brasileira, na qual concorriam grupos tanto a favor quanto contra a aproximação bilateral. Outra variável de análise foi a influência dos Estados Unidos, que estiveram atentos a todas as negociações de integração, contrários que eram à formação de blocos regionais no âmbito do subsistema de poder americano.
La fórmula del paraguas de soberanía hacia la cuestión Malvinas: ¿aplicable a la Política Exterior de Macri?
Authors: Mántaras Martina
Published: August 2019

Desde la redemocratización de la Argentina, la política exterior hacia la cuestión Malvinas es uno de los ejes más importantes analizados para determinar de qué manera nuestro país se proyecta hacia el mundo. Por ello, es necesario analizar cuál es la estrategia llevada a cabo por Mauricio Macri desde su llegada a la presidencia, en diciembre de 2015.Partiendo desde el diagnóstico de que el gobierno anterior se “alejó del mundo” y teniendo  en cuenta que el objetivo del gobierno de “Cambiemos” es lograr una reactivación económica a partir de la búsqueda de inversiones en los países occidentales desarrollados, la hipótesis del trabajo plantea que la política exterior de Macri hacia la cuestión Malvinas se asemeja, en cierta medida, a la llevada a cabo en los años 1990 por el presidente Carlos Menem, determinada a partir de la fórmula jurídico-política llamada “paraguas de soberanía” (HERRERO, 2013: 59).
DIY as Interior Design Education “Everybody Can Be Designer”
Authors: Alimin Nurhayatu Nufut
Published: August 2019

DIY (Do-it-yourself) for home decor is an activity of decorating or repairing the house or making things for home independently rather than paying someone elseto do it. DIY gains its popularity nowadays, particularly on the internet. Thephenomena of DIY probably will make interior designer lost their job becauseDIY seems can give a straightforward solution for people by self-study. Thepresent study aimed to reveal what is really going on in the field of interior designtoday. The researcher would like to analyze the difference between an interiordesigner job and DIY content sharing. The researcher collected the data fromsome popular DIY accounts (DIY; all things thrifty; and the house lars built),some practitioner‘s responses, and interview with the lecturer of the interiordesign department. The researcher attempted to answer the question usingphenomenological approach consisting of four steps namely epoche, reduction,variation of imagination, and synthesis of meaning and essence. Thisphenomenon arises since we begin to enter the fourth industrial revolution whereinternet handles everything and provides accessibility. One of the positiveimpacts of this phenomena is that people gain more understanding related tointerior design. In other words, this phenomenon makes everybody can be adesigner through DIY.
ASSESSMENT OF THE AVAILABILITY OF CT AND MRI STUDIES FOR CANCER PATIENTS IN SAINT-PETERSBURG
Authors: Pospelova Valeria N. , Minko Boris A. , Gelbutovskaya Svetlana M. , Strogonov Egor A.
Published: August 2019

Introduction. The fundamental strategic objective of the national health care was to increase the life expectancy of Russians including the early detection and treatment of cancer, remaining in recent years the leading cause of mortality, and therefore ensuring the availability of diagnostic studies for patients conducted for early diagnosis and control of treatment was extremely urgent. The objective of the study was to assess the volume and economic indicators of the availability of studies by computer tomography and magnetic resonance imaging (CT, MRI) for patients.

Material and methods. The basis for the study – all cases of CT and MRI studies in patients under the program of state guarantees of free medical care for citizens in St. Petersburg in the dynamics of 5 years. The data were statistically processed using the methods of variation statistics.

Results. Over the last 5 years in St. Petersburg, the number of medical organizations conducting CT and MRI in patients under the program of state guarantees has been doubled (CT: 37 medical organizations in 2013, 63 – in 2018; MRI: 32 medical organizations in 2013, 65 – in 2018), and there was a significant increase in the number of studies by these methods. In 2017, the number of CT scans was 106028, MRI – 107503 that was more than 2 times higher the number of studies conducted in 2013: 44799 and 56090, respectively. The role of these studies for the diagnosis of tumor process was significant: 67.3 % of CT and 46.6 % of MRI were performed for this purpose. The increase in the number of studies was accompanied by the increase in tariffs and costs of the system of compulsory health insurance for their implementation.

Conclusion. In St. Petersburg, sufficient conditions was created to ensure the volume and financial indicators of access to medical care for patients with cancer (suspected cancer) in need of CT and MRI. At following planning for the development of this type of care, it was advisable to take into account the research needs of residents of certain districts in St. Petersburg.
THE EFFECT OF JOB SATISFACTION AND ORGANIZATION COMMITMENT TO JOB PERFORMANCE THROUGH ORGANIZATIONAL CITIZENSHIP BEHAVIOR (OCB) AS MEDITATION VARIABLE (EMPIRIS STUDY ON PT. BANK MANDIRI AT JAKARTA)
Authors: Setiawan Dona Pratiwi , Gunawan Hendra
Published: August 2019

Global competition requires organization to adapt to the ever-rapidly changing ways to do business in the global environment in order to keep survive. The success of the organization does not only depend on facility and infrastructure that is available but also on their employes performance. Therefore, an organization needs to realize how important the role of their employes for the triumph of the organization. The objective of this research is to find out the effect of job satisfaction and organization commitment to job performance through Organizational Citizenship Behaviour (OCB) as meditation variable. There were 131 respondents of employee participating Respondents in this study were only limited to level of the Staff (clerk) until the Department Head only.The additional information gathered through focus group discussion with Human Resources Managers.  The summary of this research is there is effect of job satisfaction to job performance but not significant, there is effect of organization commitment to job performance but not significant, there is effect Organizational Citizenship Behaviour (OCB) to job performance, there is significant effect of job satisfaction to job performance through OCB as meditation variable and there is significant organization commitment to job performance through OCB as meditation variable.
The Role of Traditional Micro Institutions, in Income Inequality in Iran
Authors: Dadgar Yadollah , Nazari Rohollah
Published: August 2019

Purpose : Some traditional Iranian micro institutions and also some Shariah micro institutions are working informally along with formal institutions in Iran. This paper is developed to investigate the performance of institutions in question. Although. their shares in whole economy are small, these Iranian-Islamic Micro Institutions. IMI. do play their own role on changing the related economic variables, including inequality and income distribution in Iran. A specific purpose of this paper is testing the above relationships. Design/methodology/approach: In this paper firstly, and by using library studies, we explain 3 constituents of IMI. Secondly, and in order to project the impacts of variables in question on the income distribution in Iran, we gather the required data. Sources of our data include central bank of Iran, CBI, Awqaf organization and charity affairs of Iran, AOL and Statistic Centre of Iran. Thirdly, and for statistical analyzing, and statistical inferences, we employ econometric models. Finally we use vector autoregressive method (VAR), to investigate the relationship between variables, based on time series data (for 1974-2009 periods). Findings: The results of this paper show that: 1- the performance of Iranian-Islamic Micro institutions, MI including two Shariah payment subsystems and a traditional Waqf institution, reduce the inequality and improve the distributions of income.2-comparing the impact of IMI with Iranian government size ,the government size worsens the inequality of income. In other word, the bigger the government size the, worse the income inequality, but the more Waqf revenue and Shariah payments, the better income distribution.3-In Iran, these three informal institutions, surprisingly, in some dimensions, compete with formal institutions. Mean while, the deeper the belief of the people, the more efficient the
Paradigm for a Riba-free Economy
Authors: Shakespeare Rodney , Harahap Sofyan , Warsi Talib
Published: August 2019

The world's political and economic tectonic plates are shifting. The old paradigm of mainstream neoclassical economics is collapsing. Paradigmatic revolution is in the air. But what form should paradigmatic revolution take? Western 'free market' finance capitalism is the main cause of present problems and so must be rejected: and also rejected is communism/socialism which abhors Allah, is politically oppressive, and is materially inefficient. The answer lies with genuinely independent nations which have economies free from fiba. These new economies will possess their own money supply and will not rely upon financial capital coming from abroad. Eschewing riba-interest (and interest-equivalents as in forms of Islamic banking), they will be based upon the use of national bank-issued interest-free loans which can be administered by the banking system (imposing only a charge for administration). These loans are for the development and spreading of productive (and associated consuming) capacity to every individual in society. The result is a proper balance of supply and demand (as is required by Say's Theorem) and a forwarding of social and economic justice. The new economics also founds new political, social and environmental solutions.