bluuebunny/crossref_metadata_2025 huggingface dataset:
Mitochondrial calcium uniporter is essential for hearing and hair cell preservation in congenic FVB/NJ mice
Authors: Manikandan Mayakannan , Walker Steven , Deshmukh Aditi R. , Perea Elizabeth , Wang Danqi , Alagramam Kumar N. , Stepanyan Ruben
Published: May 2021

Mitochondrial Ca2+ regulates a wide range of cell processes, including morphogenesis, metabolism, excitotoxicity, and survival. In cochlear hair cells, the activation of mechano-electrical transduction and voltage-gated Ca2+ channels result in a large influx of Ca2+. The intracellular rise in Ca2+ is partly balanced by the mitochondria which rapidly uptakes Ca2+ via a highly selective channel comprised of the main pore-forming subunit, the mitochondrial Ca2+ uniporter (MCU), and associated regulatory proteins. MCU thus contributes to Ca2+ buffering, ensuring cytosolic homeostasis, and is posited to have a critical role in hair cell function and hearing. To test this hypothesis, Ca2+ homeostasis in hair cells and cochlear function were investigated in FVB/NJ mice carrying the knockout allele of Mcu (Mcu+/− or Mcu−/−). The Mcu knockout allele, which originated in C57BL/6 strain cosegregated along with Cdh23ahl allele to the FVB/NJ strain, due to the close proximity of these genes. Neither Mcu+/− nor Mcu−/− genotypes affected cochlear development, morphology, or Ca2+ homeostasis of auditory hair cells in the first two postnatal weeks. However, Mcu−/− mice displayed high-frequency hearing impairment as early as 3 weeks postnatal, which then progressed to profound hearing loss at all frequencies in about 6 months. In Mcu+/− mice, significantly elevated ABR thresholds were observed at 6 months and 9 months of age only at 32 kHz frequency. In three-month-old Mcu−/− mice, up to 18% of the outer hair cells and occasionally some inner hair cells were missing in the mid-cochlear region. In conclusion, mitochondrial Ca2+ uniporter is not required for the development of cochlea in mice, but is essential for hearing and hair cell preservation in congenic FVB/NJ mice.
A putative “chemokine switch” that regulates systemic acute inflammation in humans
Authors: Azhar Nabil , Namas Rami A. , Almahmoud Khalid , Zaaqoq Akram , Malak Othman A. , Barclay Derek , Yin Jinling , El-Dehaibi Fayten , Abboud Andrew , Simmons Richard L. , Zamora Ruben , Billiar Timothy R. , Vodovotz Yoram
Published: May 2021

Systemic inflammation is complex and likely drives clinical outcomes in critical illness such as that which ensues following severe injury. We obtained time course data on multiple inflammatory mediators in the blood of blunt trauma patients. Using dynamic network analyses, we inferred a novel control architecture for systemic inflammation: a three-way switch comprising the chemokines MCP-1/CCL2, MIG/CXCL9, and IP-10/CXCL10. To test this hypothesis, we created a logical model comprising this putative architecture. This model predicted key qualitative features of systemic inflammation in patient sub-groups, as well as the different patterns of hospital discharge of moderately vs. severely injured patients. Thus, a rational transition from data to data-driven models to mechanistic models suggests a novel, chemokine-based mechanism for control of acute inflammation in humans and points to the potential utility of this workflow in defining novel features in other complex diseases.
Mesorhizobium ciceri as biological tool for improving physiological, biochemical and antioxidant state of Cicer aritienum (L.) under fungicide stress
Authors: Shahid Mohammad , Khan Mohammad Saghir , Syed Asad , Marraiki Najat , Elgorban Abdallah M.
Published: May 2021

Fungicides among agrochemicals are consistently used in high throughput agricultural practices to protect plants from damaging impact of phytopathogens and hence to optimize crop production. However, the negative impact of fungicides on composition and functions of soil microbiota, plants and via food chain, on human health is a matter of grave concern. Considering such agrochemical threats, the present study was undertaken to know that how fungicide-tolerant symbiotic bacterium, Mesorhizobium ciceri affects the Cicer arietinum crop while growing in kitazin (KITZ) stressed soils under greenhouse conditions. Both in vitro and soil systems, KITZ imparted deleterious impacts on C. arietinum as a function of dose. The three-time more of normal rate of KITZ dose detrimentally but maximally reduced the germination efficiency, vigor index, dry matter production, symbiotic features, leaf pigments and seed attributes of C. arietinum. KITZ-induced morphological alterations in root tips, oxidative damage and cell death in root cells of C. arietinum were visible under scanning electron microscope (SEM). M. ciceri tolerated up to 2400 µg mL−1 of KITZ, synthesized considerable amounts of bioactive molecules including indole-3-acetic-acid (IAA), 1-aminocyclopropane 1-carboxylate (ACC) deaminase, siderophores, exopolysaccharides (EPS), hydrogen cyanide, ammonia, and solubilised inorganic phosphate even in fungicide-stressed media. Following application to soil, M. ciceri improved performance of C. arietinum and enhanced dry biomass production, yield, symbiosis and leaf pigments even in a fungicide-polluted environment. At 96 µg KITZ kg−1 soil, M. ciceri maximally and significantly (p ≤ 0.05) augmented the length of plants by 41%, total dry matter by 18%, carotenoid content by 9%, LHb content by 21%, root N by 9%, shoot P by 11% and pod yield by 15% over control plants. Additionally, the nodule bacterium M. ciceri efficiently colonized the plant rhizosphere/rhizoplane and considerably decreased the levels of stressor molecules (proline and malondialdehyde) and antioxidant defence enzymes viz. ascorbate peroxidise (APX), guaiacol peroxidise (GPX), catalase (CAT) and peroxidises (POD) of C. arietinum plants when inoculated in soil. The symbiotic strain effectively colonized the plant rhizosphere/rhizoplane. Conclusively, the ability to endure higher fungicide concentrations, capacity to secrete plant growth modulators even under fungicide pressure, and inherent features to lower the level of proline and plant defence enzymes makes this M. ciceri as a superb choice for augmenting the safe production of C. arietinum even under fungicide-contaminated soils.
Influence of intraoperative vasopressor use on indocyanine green fluorescence angiography: first evaluation in an experimental model
Authors: Al-Taher Mahdi , Pruimboom Tim , Schols Rutger M. , Okamoto Nariaki , Bouvy Nicole D. , Stassen Laurents P. S. , van der Hulst René R. W. J. , Kugler Michael , Hostettler Alexandre , Noll Eric , Marescaux Jacques , Diemunsch Sophie , Diana Michele
Published: May 2021

Intraoperative indocyanine green (ICG) fluorescence angiography has gained popularity and acceptance in many surgical fields for the real-time assessment of tissue perfusion. Although vasopressors have the potential to preclude an accurate assessment of tissue perfusion, there is a lack of literature with regards to its effect on ICG fluorescence angiography. An experimental porcine model was used to expose the small bowel for quantitative tissue perfusion assessment. Three increasing doses of norepinephrine infusion (0.1, 0.5, and 1.0 µg/kg/min) were administered intravenously over a 25-min interval. Time-to-peak fluorescence intensity (TTP) was the primary outcome. Secondary outcomes included absolute fluorescence intensity and local capillary lactate (LCL) levels. Five large pigs (mean weight: 40.3 ± 4.24 kg) were included. There was no significant difference in mean TTP (in seconds) at baseline (4.23) as compared to the second (3.90), third (4.41), fourth (4.60), and fifth ICG assessment (5.99). As a result of ICG accumulation, the mean and the maximum absolute fluorescence intensity were significantly different as compared to the baseline assessment. There was no significant difference in LCL levels (in mmol/L) at baseline (0.74) as compared to the second (0.82), third (0.64), fourth (0.60), and fifth assessment (0.62). Increasing doses of norepinephrine infusion have no significant influence on bowel perfusion using ICG fluorescence angiography.
Development and validation of a visual field cluster in retinitis pigmentosa
Authors: Omoto Takashi , Oishi Akio , Asaoka Ryo , Fujino Yuri , Murata Hiroshi , Azuma Keiko , Miyata Manabu , Obata Ryo , Inoue Tatsuya
Published: May 2021

The aim was to establish and evaluate a new clustering method for visual field (VF) test points to predict future VF in retinitis pigmentosa. A Humphrey Field Analyzer 10-2 test was clustered using total deviation values from 858 VFs. We stratified 68 test points into 24 sectors. Then, mean absolute error (MAE) of the sector-wise regression with them (S1) was evaluated using 196 eyes with 10 VF sequences and compared to pointwise linear regression (PLR), mean sensitivity of total area (MS) and also another sector-wise regression basing on VF mapping for glaucoma (29 sectors; S2). MAE with S1 were smaller than with PLR when between the first-third and first-seventh VFs were used. MAE with the method were significantly smaller than those of S2 when between the first-sixth and first-ninth VFs were used. The MAE of MS was smaller than those with S1 only when first to 3rd and first to 4th VFs were used; however, the prediction accuracy became far larger than any other methods when larger number of VFs were used. More accurate prediction was achieved using this new sector-wise regression than with PLR. In addition, the obtained cluster was more useful than that for glaucoma to predict progression.
Publisher Correction: Analysis of global human gut metagenomes shows that metabolic resilience potential for short-chain fatty acid production is strongly influenced by lifestyle
Authors: Jacobson David K. , Honap Tanvi P. , Ozga Andrew T. , Meda Nicolas , Kagoné Thérèse S. , Carabin Hélène , Spicer Paul , Tito Raul Y. , Obregon-Tito Alexandra J. , Reyes Luis Marin , Troncoso-Corzo Luzmila , Guija-Poma Emilio , Sankaranarayanan Krithivasan , Lewis Cecil M.
Published: May 2021

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
A rational design of layered metal–organic framework towards high-performance adsorption of hazardous organic dye
Authors: Guo Dan-Dan , Li Bo , Deng Zhao-Peng , Huo Li-Hua , Gao Shan
Published: May 2021

Acid–base stably layered L-MOF-1 has been prepared, which exhibits high adsorption capacity of 12 000 mg g−1 in 20 min in the pH range of 2.2–4.7 to CR, representing the best adsorbent with largest capacity and fastest adsorption for CR to date.
Acute ecotoxicity assessment of a covalent organic framework
Authors: P. Sárria Marisa , Vieira Ana , Lima Ângela , Fernandes Soraia P. S. , Lopes Ivo , Gonçalves Anabela , Gomes Andreia C. , Salonen Laura M. , Espiña Begoña
Published: May 2021

Covalent organic frameworks (COFs) have recently attracted increasing interest for environmental applications, hence the evaluation of their potential toxicity is of importance prior to deploying these materials in the environment.
Nanowire networks: how does small-world character evolve with dimensionality?
Authors: Daniels Ryan K. , Brown Simon A.
Published: May 2021

We show here that the connectivity of simulated quasi-3D networks of nanowires is significantly different to that of perfectly 2D networks, a result which may have important implications for applications of nanowire networks.
Covalent organic framework-based membranes for liquid separation
Authors: Zhang Sule , Zhao Shuang , Jing Xuechun , Niu Ziru , Feng Xiao
Published: May 2021

This review summarizes the synthesis and characterization methods of COF-based membranes in recent years and discusses their separation mechanism and application in liquid separation.
Colloidal magnetic brushes: influence of the magnetic content and presence of short-range attractive forces in the micro-structure and field response
Authors: Cerdà Joan J. , Bona-Casas Carles , Cerrato Antonio , Sintes Tomás , Massó Joan
Published: May 2021

Schematic diagram showing the microstructure of colloidal magnetic brushes with filaments of length N = 20 colloids as a function of the number of magnetic colloidal particles they contain, Nm, and the external magnetic field applied, H.
Strategies to promote permeation and vectorization, and reduce cytotoxicity of metal complex luminophores for bioimaging and intracellular sensing
Authors: Holden Lorcan , Burke Christopher S. , Cullinane David , Keyes Tia E.
Published: May 2021

Metal complex luminophores have emerged as effective cell imaging contrast agents over the past decade. Here we review strategies employed to promote their cell permeability and sub-cellular targeting, critical challenges in imaging applications.
Synthesis and properties of azamonocyclic energetic materials with geminal explosophores
Authors: Yang Kaidi , Bi Fuqiang , Xue Qi , Huo Huan , Bai Chao , Zhang Junlin , Wang Bozhou
Published: May 2021

Energetic pyrimidine structures with geminal explosophoric groups were achieved and their properties were investigated systematically.
Giant zirconium-bisphosphonate nano-ribbons and their liquid crystalline phase behaviour in water
Authors: Schmelter Dirk , Tagné Rodolphe Nekui , Cortes-Sanchez Hector , Schmedt auf der Günne Jörn , Welter Edmund , Hintze-Bruening Horst
Published: May 2021

Several micrometer long nano-ribbons of sodium etidronate linked Zr4O24 clusters are formed in decimolar concentration. Extraction of Na+ leads to stripping into filaments which adopt a hexagonal order and persist after neutralization with ammonia.
Effect of different oxide and hybrid precursors on MOF-CVD of ZIF-8 films
Authors: Cruz Alexander John , Arnauts Giel , Obst Martin , Kravchenko Dmitry E. , Vereecken Philippe M. , De Feyter Steven , Stassen Ivo , Hauffman Tom , Ameloot Rob
Published: May 2021

Vapor-phase fabrication of the metal–organic framework ZIF-8 through the conversion of precursors prepared by physical, atomic, and molecular layer deposition.
Sensitised lanthanide luminescence using a RuII polypyridyl functionalised dipicolinic acid chelate
Authors: Rajah Divya , Pfrunder Michael C. , Chong Bowie S. K. , Ireland Alexander R. , Etchells Isaac M. , Moore Evan G.
Published: May 2021

A [Ru(tpy)2]2+ chromophore functionalised with a dipicolinic acid chelator was prepared and investigated as an antenna for LnIII based Near Infra Red (NIR) emission, yielding relatively high sensitisation efficiencies despite the short-lived donor excited state lifetime.
Hydrosilylative reduction of carbon dioxide by a homoleptic lanthanum aryloxide catalyst with high activity and selectivity
Authors: Chang Kejian , del Rosal Iker , Zheng Xizhou , Maron Laurent , Xu Xin
Published: May 2021

A catalytic system consisting of a homoleptic lanthanum aryloxide with B(C6F5)3was found to be highly efficient in the hydrosilylative reduction of CO2under mild conditions, selectively affording CH4or bis(silyl)acetal.
Proton-controlled non-exponential photoluminescence in a pyridylamidine-substituted Re(i) complex
Authors: Martin Shea M. , Oldacre Amanda N. , Pointer Craig A. , Huang Tao , Repa Gil M. , Fredin Lisa A. , Young Elizabeth R.
Published: May 2021

An asymmetric ligand leads to non-exponential emission, breaking simple chemical intuition and design principles of ligand environments, providing a new way to deliberately tune transition metal complex reactivity for desired applications.
Azaphosphiridines: challenges and perspectives
Authors: García Alcaraz Antonio , Espinosa Ferao Arturo , Streubel Rainer
Published: May 2021

This mini-review describes a broad spectrum of synthetic strategies to access mono- and polycyclic azaphosphiridines; properties and theoretical calculations of free ligands and metal-ligated ones are discussed.
Proton conductivity in mixed cation phosphate, KMg1−xH2x(PO3)·yH2O, with a layered structure at low-intermediate temperatures
Authors: Matsuda Yasuaki , Ueda Naoya , Funakoshi Kousei , Nakajima Jun , Mori Daisuke , Taminato Sou , Higashimoto Shinya
Published: May 2021

Benitoite-type KMg1−xH2x(PO3)3·yH2O is a new proton conductor that exhibits high proton conductivity over 10−2 S cm−1 in the wide temperature range of 150–350 °C under a humidified atmosphere (pH2O = 3 kPa).
Structural characterization and osteogenic activity in vitro of novel polysaccharides from the rhizome of Polygonatum sibiricum
Authors: Liu Ji , Li Tianyu , Chen Haiyun , Yu Qian , Yan Chunyan
Published: May 2021

Polygonatum sibiricum Red., a kind of edible and medicinal plant, has a long history of use in traditional Chinese medicine and as a nutritional food additive.
Room temperature synthesized solid solution AuFe nanoparticles and their transformation into Au/Fe Janus nanocrystals
Authors: Efremova Maria V. , Spasova Marina , Heidelmann Markus , Grebennikov Ivan S. , Li Zi-An , Garanina Anastasiia S. , Tcareva Iana O. , Savchenko Alexander G. , Farle Michael , Klyachko Natalia L. , Majouga Alexander G. , Wiedwald Ulf
Published: May 2021

Solid solution AuFe nanoparticles with paramagnetic Fe atoms in the Au matrix synthesized at 25 °C transform into Janus particles upon annealing at 700 °C with the ferromagnetic bcc Fe phase epitaxially grown on fcc Au.
l-Dopa in small peptides: an amazing functionality to form supramolecular materials
Authors: Giuri Demetra , Ravarino Paolo , Tomasini Claudia
Published: May 2021

l-Dopa is an amino acid generated froml-tyrosine. Dopa derivatives are able to form amazing functional materials ranging from gels to adhesives and nanoparticles.
Glucose conjugated aza-BODIPY for enhanced photodynamic cancer therapy
Authors: Treekoon Jongjit , Pewklang Thitima , Chansaenpak Kantapat , Gorantla Jaggaiah N. , Pengthaisong Salila , Lai Rung-Yi , Ketudat-Cairns James R. , Kamkaew Anyanee
Published: May 2021

Glycoconjugate aza-BODIPY dyes (AZB-Glc and AZB-Glc-I) exhibit increased tumor uptake owing to the Warburg effect and enhanced photodynamic therapy (PDT).
Self-assembly of neutral platinum complexes possessing chiral hydrophilic TEG chains
Authors: Yoshida Masaya , Hirao Takehiro , Haino Takeharu
Published: May 2021

Neutral platinum complexes that possess chiral triethylene glycol (TEG) moieties were synthesized. The complexes formed chiral micellar aggregates in THF/water mixture.
Plasma induced acceleration and selectivity in strain-promoted azide–alkyne cycloadditions
Authors: Warther David , Dursun Enes , Recher Marion , Ursuegui Sylvain , Mosser Michel , Sobska Joanna , Krezel Wojciech , Chaubet Guilhem , Wagner Alain
Published: May 2021

We report the unexpected acceleration of strain-promoted azide–alkyne cycloaddition in human plasma compared to classical solvent systems. Besides fast kinetics, human plasma also allows for discrimination between two azides in competition reaction.
Antitumor activity of tridentate pincer and related metal complexes
Authors: Wu Shulei , Wu Zaoduan , Ge Qianyi , Zheng Xing , Yang Zehua
Published: May 2021

Pincer and related metal complexes containing tunable tridentate ligand frameworks display promising antitumor activity.
A computational study of site-selective hydrogen abstraction by sulfate radical anion
Authors: Ueda Masahiro , Kitano Atsuki , Matsubara Hiroshi
Published: May 2021

Ab initio and DFT calculations revealed that β-hydrogen abstraction would be favourable, which supports experimental findings (i.e. β-selective abstraction).
Facile one-pot synthesis of diarylacetylenes from arylaldehydesviaan addition-double elimination process
Authors: Chen Jianyang , Zhang Xuan , Wu Jiajun , Wang Rui , Lei Chunlin , An Yanan
Published: May 2021

A practical one-pot reaction has been developed to synthesize diarylacetylenes directly from arylaldehydes.
An unconventional route to an ambipolar azaheterocycle and its in situ generated radical anion
Authors: Das Sarasija , Choudhury Anwesha , Mandal Arnab , Kumar Chandan , Ranjan Sahoo Smruti , Bedi Anjan , Shekhar Karmakar Himadri , Gopal Ghosh Nani , Dey Somnath , Krishnan Iyer Parameswar , Bhattacharyya Sayan , Zade Sanjio S.
Published: May 2021

FeCl3 mediated C–N coupling leads to an azaheterocycle, which undergoes one-electron reduction to form a fairly stable radical anion in situ. The azaheterocycle material showed balanced ambipolar charge transport in SCLC devices.
Extraction of the trivalent transplutonium actinides americium through einsteinium by the sulfur donor Cyanex 301
Authors: Bessen Nathan , Yan Qiang , Pu Ning , Chen Jing , Xu Chao , Shafer Jenifer
Published: May 2021

When extracting metals with the sulfur donor ligand, Cyanex 301 (bis(2,4,4-trimethylpentyl)dithiophosphinic acid), a transition in the coordination mode of extracted complexes has been observed between Eu and Gd, but not within the actinide series.
A CoSe2-based 3D conductive network for high-performance potassium storage: enhancing charge transportation by encapsulation and restriction strategy
Authors: Zhao Jing , Wu Hu , Li Long , Lu Shiyao , Mao Heng , Ding Shujiang
Published: May 2021

The 3D conductive network improves electronic conductivity, and the gap between graphene layers avoids spalling, showing excellent potassium storage performance.
Catalytic (3 + 2) annulation of donor–acceptor aminocyclopropane monoesters and indoles
Authors: Pirenne Vincent , Robert Emma G. L. , Waser Jerome
Published: May 2021

A catalytic dearomatization of indoles with D–A aminocyclopropane monoesters for the synthesis of highly substituted indolines.
Manipulating valence and core electronic excitations of a transition-metal complex using UV/Vis and X-ray cavities
Authors: Gu Bing , Cavaletto Stefano M. , Nascimento Daniel R. , Khalil Munira , Govind Niranjan , Mukamel Shaul
Published: May 2021

We demonstrate how optical cavities can be exploited to control both valence- and core-excitations in a prototypical model transition metal complex, ferricyanide ([Fe(iii)(CN)6]3−), in an aqueous environment.
Hydrogen-bond-induced selectivity of a head-to-head photo-dimerisation of dialkynylanthracene – access to tetradentate Lewis acids
Authors: Niermeier Philipp , Maibom Kristina A. M. , Lamm Jan-Hendrik , Neumann Beate , Stammler Hans-Georg , Mitzel Norbert W.
Published: May 2021

Preorganised by hydrogen bonds and π-stacking, 2-hydroxypropylalkyne-protected 1,8-alkynylanthracene photo-dimerises preferably in head-to-head configuration; the resulting rigid organic frameworks can be converted into tetradentate boron Lewis acids.
A self-supported FeNi layered double hydroxide anode with high activity and long-term stability for efficient oxygen evolution reaction
Authors: Su Mingyu , Zhu Shengli , Cui Zhenduo , Li Zhaoyang , Wu Shuilin , Guo Meiqing , Jiang Hui , Liang Yanqin
Published: May 2021

The FeNi-layered double hydroxides nanoparticles with high oxygen evolution reaction activity and prominent catalytic lifetime were first self-assembled on FeNi foam. This catalyst has a promising future for large-scale non-precious materials in the industry.
Interface-induced hysteretic volume phase transition of microgels: simulation and experiment
Authors: Kolker Jannis , Harrer Johannes , Ciarella Simone , Rey Marcel , Ickler Maret , Janssen Liesbeth M. C. , Vogel Nicolas , Löwen Hartmut
Published: May 2021

Interface induced hysteresis in the volume phase transition of microgels. Top and side view of microgel configurations.
Conformational behavior and self-assembly of disjoint semi-flexible ring polymers adsorbed on solid substrates
Authors: Zhu Yu , Kumar P. B. Sunil , Laradji Mohamed
Published: May 2021

The conformational behavior and spatial organization of disjoint semi-flexible ring polymers, which are fully adsorbed on solid substrates, are strongly affected by the combined effects of bending stiffness and areal density.
Translational dynamics of a rod-like probe in supercooled liquids: an experimentally realizable method to study Stokes–Einstein breakdown, dynamic heterogeneity, and amorphous order
Authors: Mutneja Anoop , Karmakar Smarajit
Published: May 2021

We have proposed a novel method to study Stokes–Einstein Breakdown, Dynamic Heterogeneity, and Amorphous Order in supercooled liquids using elongated particles. Simplicity of the method will be attractive for single-molecule experiments in future.
A fourth‐order incremental ADC in three‐step
Authors: Huang Jia‐Sheng , Kuo Shih‐Che , Kao Chia‐Wei , Huang Yu‐Cheng , Hsu Che‐Wei , Chen Chia‐Hung
Published: May 2021

This letter presents a second‐order incremental ADC (IADC) operated in three steps, which extends the performance of a second‐order IADC close to that of a fourth‐order IADC with only two amplifiers. It performs a second‐order noise‐shaping quantization in the first step operation. Reusing the same hardware, the circuit is reconfigured to perform fine quantization as a first‐order IADC in the second and third step. Within a conversion time of 60 clock periods (oversampling ratio OSR = 60), 35 dB signal‐to‐quantization‐noise ratio is boosted. The proposed topology is very suitable for low‐bandwidth high‐resolution data conversion.
Study on Dynamic Response Characteristics of Rock Slope
Authors: Zhanling Fu , Jingquan Cao , Wuping Gao , Xinqiang Yao
Published: May 2021

After the wenchuan earthquake, the dynamic response law of rock slope under the action of dynamic load is a very concerned and urgent problem in the field of seismic engineering. This paper analyzed the dynamic response law of simplified rock slope under the cosine wave dynamic load by numerical simulation with FLAC3D software. This research emphatically analyzed the variation law of amplification coefficient of seismic displacement, acceleration and velocity of rock slope under the condition of different slope height, slope angle, dynamic load period and dynamic load amplitude, which provides a basis for reducing seismic damage of slope area and seismic design of engineering structure.
Study on Seismic Spectrum and Amplification Effect of Soft Soil in Tianjin New Coastal Area
Authors: Zhanling Fu , Jingquan Cao , Wuping Gao , Xinqiang Yao
Published: May 2021

Tianjin new coastal area has a large area of soft soil with high salinity and high humidity. This kind of foundation has unique spectral characteristics and amplification effect on ground motion, which is a deep factor to increase earthquake damage. Based on the geotechnical data of Tianjin new coastal, we established a simplified calculation model and adopted a nonlinear method to study the seismic spectrum and amplification effect of three typical soft soil foundation with different thickness in Tianjin new coastal area, which real earthquake motion EL-Centro seismic wave passing through, that is in order to provide a basis for the seismic design of engineering structures in this area. The results show that: The soft soil foundation in Tianjin new coastal area has an obvious amplification effect on EL-Centro wave within 8HZ, while the seismic wave greater than 8HZ rapidly attenuates after filtering through the soft soil, and the amplitude greatly reduced. After the EL-Centro wave passes through the three types of soft soil, the acceleration, velocity and displacement coefficient are always in the state of amplification. The amplification coefficient is the largest in the muddy soil, followed by the muddy clay and the smallest in the silty clay. The softer the soil, the more obvious the amplification effect will be. Except the displacement amplification coefficient does not change much with the increase of soft soil thickness, the acceleration and velocity coefficients increase gradually with the increase of soft soil thickness, and the amplification effect is obvious after reaching the surface.
Sustainability Assessment Based on Weighing Method of Combined Subjective-objective——Case of Shaanxi Province in Northwestern China
Authors: Li Shengting , Zhou Xiaowei
Published: May 2021

Based on the principle of the triple bottom line (economy, society and environment), considering about energy export region of Shaanxi actual situation, this paper constructed a comprehensive assessment for sustainability of industrial ecosystem (SIE) by weighing method of combined subjective-objective (CSO) and based on the data from 2008 to 2018. The research results indicated that the sustainable development of industrial ecosystem continues to improve and the policy guidance plays a significant role in this process. Many policy measures had characteristic of Shaanxi, such as the strategies of energy industry-- stable production and quality improvement, structural optimization of non-energy industry and the leading role of major project.
A Meta-Analysis of the Effect of Acceptance Commitment Therapy on Obsessive-Compulsive Disorder
Authors: Ai Xiong , Maorong Hu
Published: May 2021

Objective: this study aimed to explore the effect of acceptance commitment therapy (ACT) on Obsessive compulsive disorder (OCD). Methods: randomized controlled trials of the effect of ACT on obsessive-compulsive disorder were searched in the Cochrane Library, PubMed, Web of Science, EMBASE and Google Scholar databases, and the measurement data of the Yale-Brown Obsessive Scale(Y-BOCS) test scores were meta-analyzed using Revman5.3 software. Results: The study included 5 eligible literatures, with a total sample of 275 persons. The results of meta-analysis on the effect of ACT alone showed that ACT had a better effect on OCD than other treatment methods (MD = -3.76, Z = 4.41, P≤0.05). Meta-analysis results of ACT combined SSRIs therapy showed that ACT combined therapy was better than SSRIs alone (MD = - 7.18, Z =6.59, P ≤ 0.05). Conclusion: acceptance commitment therapy can effectively treat OCD.
Short-term Traffic Flow Prediction Based on Deep Learning Model
Authors: Ren Nv Er , Tang Lan Wen , Yin Yue Hua , Wang Yao Dong
Published: May 2021

In order to improve the prediction accuracy of the intelligent transportation system and provide effective support for the dynamic control and guidance of the highway management department, with the goal of minimizing the short-term traffic flow prediction error, the long-term short-term memory (LSTM) model is trained, fitted and adjusted based on the deep learning framework. In addition, the established model is used to predict the short-term traffic flow of the expressway during holidays and working days. At the same time, the traffic flow was simulated by microscopic simulation software to further verify the feasibility of the LSTM algorithm.
Research on the Integration of China's Tourism Industry and Financial Industry under the Background of “the Belt and Road”
Authors: Weiling Su , Tongtong Ren
Published: May 2021

Under the background of "the Belt and Road", the rapid development of tourism and financial industry in China has made important contributions to the economic and cultural construction of "the Belt and Road ". Through the construction of coupling correlation model and coupling index system, this paper conducts an empirical analysis on the integrated development of tourism and financial industry in China from 2013 to 2017 under the background of "the Belt and Road". The results show that China's tourism and financial industry have developed rapidly in the period of 2013-2017, and there is a significant coupling relationship between them. However, there is a lag in the development of financial industry in 2013-2014 and a lag in the development of tourism industry in 2015-2017. In general, under the background of "the Belt and Road", China's tourism and financial industry continue to develop, and the links and interactions between the two industries are getting stronger and stronger. The two industries promote each other, and finally achieve the high-quality coordinated development of tourism and financial industry.
Economic growth, distribution policy and other factors: key elements in poverty alleviation
Authors: Zhu Silin , Rishita Nandagiri , Liu Zhiyan , Zhu Yian
Published: May 2021

Poverty, as a universal problem, has been widely concerned by scholars all over the world. This essay argues how economic growth, distribution policy and other factors affect poverty reduction issues. Firstly, this article will briefly introduce the context of the poverty issue and how economic growth influences poverty reduction. Secondly, two exceptional cases and three non-economic factors will be analyzed to test whether distribution policy and other factors can also influence or dismiss poverty. Finally, this article will conclude that rapid economic growth is good for poverty alleviation but not all the needs. The distribution policies and other non-economic factors may also influence the link between economic growth and poverty reduction.
Strategic Analysis of the Catering Industry under Covid-19: a Case Study in China
Authors: Xiong Xiaoxiao , Yao Ruoyu
Published: May 2021

In the normal phenomenon, the restaurant industry strategic planning and future development trends are diverse, therefore, it is difficult to choose for. Existing literature does not provide effective guidance for the implementation of strategic plans in the catering industry under coVID-19. Taking RJ Restaurant in Chongqing as an example, this paper uses the method of combining qualitative and quantitative methods to study the difficulties that restaurants are facing now. This study clarifies that at the strategic level, the belief of medium-sized private restaurants to survive coVID-19 needs be based on identifying their deficiencies to establish cost strategy and differentiation strategy, which includes emphasizing the future development trends of intelligent use and "customized" services. There are two contributions to this study. First of all, this study provides a stereotyped municipal infrastructure framework for the study of private restaurants. In addition, this study studied the literature on strategic analysis of the catering industry from the perspective of coVID-19.
Research of the Impact of Big Data on Enterprise Import and Export Based on Economic Globalization
Authors: Yan Zhang
Published: May 2021

At present, the integration of information technology is an inevitable trend under the background of economic globalization. Big data has a great impact on the import and export of enterprises. The impact on the import and export of enterprises is not only the support of information, but also the support of technology. The article will effectively combine the economic globalization and big data to conduct in-depth research and analysis[1].
Regional Economic Prediction Model and Empirical Research Based on Big Data Technology
Authors: Luo Yulin , Huang Tianming
Published: May 2021

In order to test the prediction effect of big data technology on regional economy, this paper uses Engle-Granger test to explore the relationship between house prices in Xiangyang City and big data represented by search index. This paper selects the house price data from April 2015 to February 2020, and uses the Baidu Index with a correlation coefficient greater than 0.5 to build a search index, so as to test it empirically. The empirical results show that big data has a strong prediction for house prices in small and medium-sized cities, and the search index constructed by the weight of correlation coefficient is better.
The impact of training on the improvement of skills of manufacturing skilled workers in the context of big data and legal consideration
Authors: Hongfei Xu
Published: May 2021

With the key words of skilled worker training, evaluation, innovation, mobility and motivation, three sets of relevant survey questionnaires were designed for skilled workers, managers and enterprises, and they were used in more than ten enterprises in Hubei. In the questionnaire data statistics, according to the principle of "single-question compliance", data that does not meet the requirements of the topic selection is eliminated. Based on high-quality development and manufacturing in Hubei Province, this article summarizes and puts forward the problems that exist in the training process and the improvement of skills of manufacturing skilled workers in Hubei Province under the background of big data through the analysis of effective data and field investigations. Thinking about the corresponding countermeasures from the legal level.
Multi objective optimization of ship spare parts maintenance based on Improved Genetic Algorithm
Authors: Xiao Bin , Liu Chang , Jiang Tiejun
Published: May 2021

For ship equipment turnover spare parts, if the maintenance interval is too long, the safety and working ability will be reduced; if frequent maintenance is performed, it will cause much waste. Therefore, it is necessary to determine the appropriate maintenance interval for resource optimization. The article analyzes the factors of turnover spare parts maintenance resource optimization. It establishes an equipment parts maintenance time resource optimization model based on maintenance theory and multi-objective decision-making methods, which can ensure the familiar training environment, maintenance type, and update type preventive maintenance mode The satisfaction is the largest, and group decision making and improved genetic algorithm are used to solve the optimal satisfaction. Finally, the effectiveness of the model is verified with examples of ship equipment spare parts.
Visualization Research and Analysis of Turnover Intention
Authors: Liu Hui , Liu Yan
Published: May 2021

Turnover intentions plays an important role in predicting employee turnover behavior. In order to accurately identify research hotspots and evolutionary trends in turnover intention, this study uses the literature on departure inclination in the Web of Science core collection as the research object and uses CiteSpace.5.5 for visual analysis. The research results show that the research topics of turnover intention can be summarized into three aspects: the factors affecting turnover intention, the consequences of turnover intention, and the research methods. Although some researches on turnover intention have achieved certain results, there are still some problems such as lack of cooperation among researchers, few personal influence factors, and few studies on how to reduce turnover intentions. Based on this, some suggestions for future research directions are proposed.
Stackelberg Model of Anti-terrorism Resource Allocation in Express Transportation Security Checks
Authors: Bu Bing , Wang Lei , Pi Zhenyang , Fang Weiguo
Published: May 2021

The problem of anti-terrorism security checks of express transportation becomes more and more severe under the Internet shopping model. In this paper, a Stackelberg game model of anti-terrorism resource allocation in express transportation security checks is built to discuss, in terms of single and multiple routes, the optimal resource allocation of express company (defender) including physical security measures, in-box sensor technology, non-intrusive security measures at terminal distribution sites and handover course. It shows that, for the single route, express company should trade off the security costs among the first, second and third level security measures, and should allocate the same security costs of physical security measures for every distribution site. For the multiple routes, the transportation route that terrorists insert the hazardous materials has the lowest probability of physical security measures, and therefore is utilized by terrorists. Thus, the optimal allocation plan of security resources should be the same security costs of non-intrusive security measures at the final distribution sites (the third level security measure) among each transportation routes.
Volatility Forecasting of China Silver Futures: the Contributions of Chinese Investor Sentiment and CBOE Gold and Silver ETF Volatility Indices
Authors: Hu Wenbin
Published: May 2021

This paper is to detect the role of CBOE gold ETF volatility index (GVZ), CBOE silver ETF volatility index (VXSLV), and constructed Chinese investor sentiment (CnSENT) on the volatility forecasting of China silver futures over daily, weekly and monthly horizons. Different types of HAR models and ridge regression models are utilized to do the analysis, and the out-of-sample R-square statistics and different rolling window sizes are used to ensure the robustness of the conclusion. The empirical results suggest that GVZ and VXSLV have the explanatory power on the China silver futures. Particularly, VXSLV has a better performance than GVZ. However, the predictive power of CnSENT is doubtful as some results indicate that it cannot improve the prediction accuracy. Additionally, the ridge regression method does not achieve a better result than all types of HAR models.
Emergency decision-making method based on multi-attribute intuitionistic fuzzy and evidence theory
Authors: Xu Xiaoyue , Fang Danhui , Song Yinghua
Published: May 2021

Multi-attribute emergency decision-making problems have the characteristics of incomplete information and shortage of response time. Evidence theory can effectively express uncertain information in the decision-making process. However, evidence theory requires that the condition of evidence independence is met, and the evaluation information of experts is often vague. Therefore, an emergency decision-making method based on intuitionistic fuzzy sets and evidence theory is proposed. First, each expert gives an intuitionistic fuzzy evaluation of each emergency plan. Secondly, the proposed intuitionistic fuzzy similarity calculation method is used to obtain the similarity between experts and determine the expert weight. The attribute weight is known, the intuitionistic fuzzy evaluation is converted into a Mass function, and the evaluation of expert's decision-making plan is revised and fused using evidence theory to obtain the final decision. Finally, an example analysis proves that the model is feasible and effective.
Quantitative Analysis of the Internet Economy
Authors: Yu Zhuo
Published: May 2021

Since the beginning of the 21st century, China has made great strides in the development of the Internet, which has had an extensive and far-reaching impact on the economy and society. This has led to a growing number of scholars’ attention paid to issues related to the Internet and economic development. The Internet provides a superior information platform for all economic entities, enabling economic exchanges to transcend the constraints of time and space. And on the basis of expanding the scope of transactions, reducing transaction costs, it deepens the social division of labor, creating more job vacancies, which is one of the crucial driving forces of economic development in the new era, whose role has been irreplaceable: On the one hand, as an important symbol of the knowledge economy era and the main carrier of information life, the Internet serves as the bearer of the development of a new industry - the Internet industry, making it grow and expand at an alarming rate and transform into a new force in China’s industry, injecting vitality into economic growth; besides, the Internet, by virtue of its information platform and technological advantages, has brought opportunities and changes to traditional industries in many aspects. As can be seen, it is no longer possible to study economic growth without paying attention to the role of Internet factors. Therefore, this paper builds an economic growth model, selects appropriate variables and data, studies the magnitude of Internet development’s contribution to the economy, and discusses the characteristics of the Internet’s economic promotion effect under the analysis of the current situation, characteristics and trends of China’s Internet development.
The development of e-commerce by web celebrity live webcast with goods
Authors: He Hui
Published: May 2021

Online celebrities with goods refers to celebrities with the Internet "+" era background and their own unique advantages, through micro blog, wechat, short video and live broadcast platform to promote the sales of goods from the media. The purpose of this paper is to explore the development prospect of ecommerce under the background of live broadcast of online celebrities with goods. This paper discusses the impact of online celebrity live broadcast on e-commerce and the existing problems, and puts forward the corresponding solutions for reference.
The Construction and Effectiveness of Regional Cultural Confidence Strategy in the Context of Brand Internationalization: Based on Big Data
Authors: Zhao Weihong , Xie Shengcheng , Jin Hong
Published: May 2021

Place brand cannot be built without regional culture, and regional cultural confidence from excellent regional culture is an important force for place brand internationalization and win host country consumers. Alao, regional culture also plays an important role in the informatization of brand matrix support. Based on the perspective of legitimacy, this paper puts forward the connotation of regional cultural confidence strategy and discusses the specific effectiveness of regional cultural confidence strategy. In the future, the regional cultural confidence strategy from the perspective of legitimacy can be exploratively constructed and tested based on big data, which is of great significance for enriching relevant theories of local brand internationalization strategy.
Research on the Application of Big Data Statistics in the Field of Economic Management
Authors: Du Mingyu
Published: May 2021

In the context of continuous social and economic development, the integration of statistics and economic management has been strengthened. Big data statistical technology has found economic development laws from many data, and its effect in macroeconomic analysis is extremely high. This article focuses on the application of big data statistical methods and existing problems in the field of economic management and proposes corresponding countermeasures.
Research on Impact Factors of Smart Elderly Care Mode and the Corresponding Industry: ──Taking Questionnaire Data of Some Cities in Jiangsu Province as An Example
Authors: Liu Fengjuan , Liu Yuechen , Yang Chun
Published: May 2021

With the development of Internet of things technology, the smart elderly care mode is attracting more and more attention. Based on the questionnaire data of adult residents in some cities of Jiangsu Province, this paper analyzes the multiple linear regression model between the intelligent elderly care mode and its possible influencing factors. And it can be found that for participants aged 59 and under, their educational level, blood type, professional identity and age have a significant impact on intelligent old-age care mode. For participants aged 60 and over, only their educational level and age have a significant impact on the smart old-age care approach. Finally, this paper puts forward some suggestions about the development of industries related to intelligent elderly care to build an integrated intelligent community old-age care pattern, integrated pattern of intelligent home-based care or integrated smart home-based care service center, adjust and perfect the existing elderly care institutions, and improve intelligence old-age care institutions pattern to promote the development of intelligent industry related to smart elderly care.