bluuebunny/crossref_metadata_2025 huggingface dataset:
Analyzing Tea Tourism Products and Experiences
From India and Turkey
Authors: Yılmaz Gökhan , Kumar Dixit Saurabh
Published: May 2023

Tea is considered an important symbol of expression of socio-cultural heritage, community bonding, ethnicities, and customs to strengthen local place identity. Tea tourism offers an engaging and enduring gastronomic experience due to the active participation of tourists. This study aims to identify the key destination tea tourism products or experiences. This study uses a qualitative research approach to identify the prime tea tourism products and experiences from two important tea-growing nations, i.e., India and Turkey, ranked second and fifth in global tea production, respectively. The research findings present four main categories: facilities, activities, tours, training, Observation, and twenty-five sub-categories relating to tea tourism products and experiences. This study also strives to discover the contribution of tea tourism products or experiences in the tours conducted by Indian and Turkey travel agencies. This study is one of the first studies to examine the selected elements of tea tourism at the destination. The results will contribute to several theoretical and practical implications concerning tea tourism in tea-producing countries. The study will also offer essential insights into how travel agencies may use tea tourism products and experiences efficiently in packaging their tours.
KEPATUHAN DAN LUARAN TERAPI PADA PASIEN DIABETES MELITUS TIPE 2 PENGGUNA INSULIN DI APOTEK X YOGYAKARTA
Authors: Fathurrahman Muhammad , Ardhiani Menit , Faridah Imaniar Noor , Dania Haafizah , Irham Lalu Muhammad , Perwitasari Dyah Aryani
Published: May 2023

Diabetes melitus (DM) adalah suatu gangguan metabolisme yang ditandai dengan gula darah yang naik secara berlebihan akibat gangguan sekresi insulin, kerja insulin, atau keduanya. Gangguan metabolisme karbohidrat, lemak dan protein pada penderita diabetes disebabkan oleh kurangnya aktivitas insulin pada sel target. Tujuan penelitian ini untuk mengetahui hubungan antara kepatuhan penggunaan insulin dengan luaran terapi klinis di Apotek X. Penelitian ini menggunakan desain studi Cross Sectional dan pengambilan data dilakukan secara prospektif menggunaka kuisioner Medication Adherence Report Scale (MARS) dan data hasil laboratorium. Analisa dapat dilaksanakan menggunakan uji Chi-square. Hasil penelitian menunjukkan kepatuhan tinggi  sebesar 6 responden (30%) dan kepatuhan rendah sebesar 14 responden (70%). Uji chi-square menunjukkan hubungan antara penggunaan insulin dengan HbA1c dengan p-value = 0,01, hubungan antara penggunaan insulin dengan Gula Darah Puasa dengan p-value = 0,024, dan tidak ada hubungan antara penggunaan insulin dengan Gula Darah Sewaktu dengan p-value = 0,807. Hal tersebut menunjukkan bahwa kepatuhan penggunaan insulin mempengaruhi terkontrolnya luaran terapi klinis pasien.
Kata Kunci : Diabetes Melitus, Insulin, HbA1c, GDP, GDS, Apotek
O STREET VIEW COMO RECURSO DIDÁTICO DE GEOGRAFIA NO ENSINO FUNDAMENTAL II
Authors: Santos Ana Caroline Pereira dos , Queiroz Antônia Márcia Duarte
Published: May 2023

Este artigo é resultante de Trabalho de Conclusão de Curso de pós-graduação em Geografia e tem o objetivo de apresentar as reflexões sobre a importância das tecnologias educacionais nas regências de aulas na educação básica. Como práticas diferenciadas, seguem evidenciando a articulação entre teoria e prática, demonstrando a importância da imersão de diversas tecnologias digitais no cotidiano escolar. A metodologia utilizada foi a qualitativa, tendo como procedimentos metodológicos a pesquisa bibliográfica, observação participante e análise da experiencia. O suporte teórico se fez presente a partir das contribuições da categoria geográfica espaço, mediante a percepção da cidade em foco, e suas transformações. A reflexão sobre os aplicativos utilizados, por meio do celular em sala de aula, apesar das dificuldades sentidas, se mostra eficiente com inúmeras contribuições para o fazer e ensinar geográficos. Por outro lado, também traz à tona, a difícil realidade do acesso as Tecnologias educacionais nas escolas da educação básica também no setor privado.
O ENSINO DE GEOGRAFIA COM O AUXÍLIO DE DESENHOS ANIMADOS:
O FILME “OS SEM FLORESTA” COMO UMA PROPOSTA DE MATERIAL DIDÁTICO PARA 7º ANO DO ENSINO FUNDAMENTAL
Authors: Sousa Lucas Ricardo Ribeiro de , Costa Kênia Gonçalves
Published: May 2023

A Geografia é uma ciência importante que contribui para o entendimento do espaço geográfico e suas relações entre sociedade e as questões socioambientais e culturais. Nesse sentido, com base na Base Nacional Comum Curricular (BNCC) (Brasil, 2018), os conhecimentos geográficos contribuem para que os/as estudantes possam compreender o mundo em que vivem e participar de forma mais ativa nas atividades voltadas para o funcionamento das questões presentes neste, além de corroborar para o exercício das diversas formas de expressões.O Ensino de Geografia permite estratégias de construção de conhecimento articulando vários saberes, competências e habilidades. Dessa maneira, a BNCC trabalha as divisões das habilidades a partir de códigos, pois é através deste que os/as professores/as vão ter um suporte norteador para dar prosseguimento dos conteúdos de acordo com a faixa de idade e a série que os/as alunos/as estão inseridos.[...]
A RELAÇÃO ENTRE RECURSOS DIDÁTICOS E AS ESTRATÉGIAS DOCENTES PARA O ENSINO E A APRENDIZAGEM DE GEOGRAFIA
Authors: Andrade Denise da Silva , Sobrinho Orimar Souza Santana
Published: May 2023

Este trabalho é o resultado da conclusão da Pós-graduação Lato Sensu em Geografia da Universidade Federal do Norte do Tocantins (UFT) em 2022. Em diversas oportunidades deste trajeto despertou nosso interesse em compreender o papel do professor dos Anos Iniciais do Ensino Fundamental, no que se refere às estratégias de ensino e aprendizagem dos conteúdos de Geografia a partir de seus conhecimentos formativos. Para Aragão e Mendes Neta (2017), na tentativa de produzir algum conhecimento é necessário,[...] lançar e aprofundar olhares para alguns aportes teóricos - metodológicos específicos das ciências humanas fundamentais para o desenvolvimento de uma pesquisa científica. Precisamos inicialmente ter a definição de um tema apontado por um problema (questão) que nos toca, que nos sensibiliza por alguma razão, que nos aflige ou que pretendemos construir e indicar ou sugerir alguma compreensão e/ou solução para tal fato ou fenômeno. (Aragão; Mendes Neta, 2017, p. 27).
ENTRE A TEORIA E A PRÁTICA DE ENSINO DE GEOGRAFIA
Authors: Martins Liane de Souza , Queiroz Antônia Márcia Duarte , Costa Mota Wanessa Lorenna de Sousa Miranda
Published: May 2023

O objetivo deste trabalho é refletir sobre as ações educativas realizadas na Escola Estadual Jardim Paulista. As experiências do Programa Residência Pedagógica - RP, do núcleo de Geografia na Universidade Federal do Tocantins, na cidade de Araguaína-TO. Em específico, dialogamos com os resultados para além das concepções pedagógicas, socializando práticas e atividades de ensino. Essa experiência evidenciou a articulação teoria e prática, ao revelar a realidade do ensino na educação básica. Assim, promovendo a interação efetiva entre a academia, o licenciando e o futuro campo de atuação profissional. Dessa forma, revelou diversas dificuldades conceituais e práticas da docência na educação básica, como também contribuiu para reflexão, da reformulação contínua de boas práticas de ensino e aprendizagem mediante a realidade escolar, no qual o estudante está inserido.
Clinical-evolutionary considerations in Duchenne Dystrophy
Authors:   2nd Pediatric Clinic, Emergency County Hospital, University of Medicine and Pharmacy, Craiova, Romania, Singer Cristina Elena , Cosoveanu Simona ,   2nd Pediatric Clinic, Emergency County Hospital, University of Medicine and Pharmacy, Craiova, Romania, Petrescu Ileana Octavia ,   2nd Pediatric Clinic, Emergency County Hospital, University of Medicine and Pharmacy, Craiova, Romania, Singer Maria ,   ”Dr.Carol Davila” Central Military Emergency Hospital, Bucharest, Romania, Dobrescu Amelia ,   Department of Medical Genetics, County Emergency Clinical Hospital, University of Medicine and Pharmacy, Craiova, Romania, Popescu Mihaela ,   Endocrinology Clinic, University of Medicine and Pharmacy, Craiova, Romania, Popescu Alin Iulian Silviu ,   Medical Clinic, University of Medicine and Pharmacy, Craiova, Romania
Published: May 2023

Duchenne muscular dystrophy (DMD) is a severe, progressive and incurable X-linked genetic disorder. The article presents 18 children with DMD admitted between 2016-2022 in the Pediatric Clinic II, Emergency County Hospital in Craiova. The study looked at: the distribution according to residence, the average age when they walked, when they were diagnosed and when they walked in a wheelchair, heredocollateral and pathological antecedents, clinical manifestations, nutritional status, genetic tests and the evolution of these patients.
Is measuring serum ammonia helpful in patients with liver cirrhosis?
Authors:   Neurology Department, Fundeni Clinical Institute, Bucharest, Romania, Lupescu Ioan-Cristian ,   ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Iacob Maria Speranta ,   Gastroenterology Department, Fundeni Clinical Institute, Bucharest, Romania,   ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Gheorghe L. ,   Gastroenterology Department, Fundeni Clinical Institute, Bucharest, Romania,   ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
Published: May 2023

Background. Ammonia has been traditionally viewed as one of the main culprits for the development of hepatic encephalopathy. In the setting of liver cirrhosis or portal-systemic shunting, hepatocytes fail to metabolize ammonia, and thus excess ammonia reaches the systemic circulation, and from there, the brain. Material and methods. We performed a descriptive study involving 28 adult patients with liver cirrhosis. None of the patients had overt hepatic encephalopathy at the time of assessment, as judged by the West Haven criteria. Severity of liver cirrhosis was measured through the Child-Pugh and MELD scores. Serum ammonia was measured by venous sampling. Results. Mean age of the patients was 50±10 years-old. There were 68% males (n=19). Mean MELD score was 17±5 points. Mean Child-Pugh score was 8±2 points. Mean serum ammonia level was 76±37 μmol/L (range: 34-204 μmol/L). Serum ammonia levels correlated significantly with both scores of liver disease severity, more so with MELD (R=0.61, p=0.0005), than with the Child-Pugh score (R=0.38, p=0.04) Conclusions. We reaffirm the importance of measuring blood ammonia in patients with liver cirrhosis, since it is a helpful biomarker which correlates with liver disease severity and hepatic encephalopathy.
Regenerative medicine options in treating premature ovarian failure
Authors:   ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Busuioc Roxana-Elena , Paduraru Dan Nicolae ,   ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   General Surgery Department, University Emergency Hospital of Bucharest, Romania, Stanescu Ana Maria Alexandra ,   ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Barbalata Didina Catalina ,   ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania, Musat Florentina ,   ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   General Surgery Department, University Emergency Hospital of Bucharest, Romania, Albu Andreea Ruxandra ,   ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   Obstetrics and Gynecology Department, University Emergency Hospital of Bucharest, Romania, Andronic Octavian ,   ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,   General Surgery Department, University Emergency Hospital of Bucharest, Romania
Published: May 2023

Infertility is generally defined as the failure to achieve a pregnancy after 12 months or more of regular unprotected sexual intercourse. premature ovarian failure (POF) is a cause of female infertility, being estimated to affect 1% of the general population. This condition represents a loss of hormonal and germinative activity of the ovaries due to a lack in the number of active follicles in women under 40 years old. Regenerative medicine represents a complex therapeutic option and it consists of technologies such as the use of stem cells, tissue engineering, and gene therapy alone or in different combinations. Although the boundaries of regenerative medicine are not clearly outlined at present, this paper is aiming to review its possibility of treatment in the future in what concerns POF, focusing more on the use of stem cell therapy. Stem cell therapy could be a feasible therapeutic approach for POF as the cells can be easily obtained. However, additional clinical studies are needed because until now the majority of the literature focuses on animal models for the evaluation of the role of stem cells on treating POF. Additionally, the platelet-rich plasma (PRP) approach for POF should be kept in mind as it was shown to be useful in the regeneration of multiple types of tissue.
Credit Ratings and Firm Innovation
Authors:   Academic Society of Global Business Administration, Na Jaeseog , Joe Yongmin
Published: May 2023

This study examines the impact of credit ratings on corporate innovation activities. A sample of domestic securities-listed companies is selected, and changes in innovation activities are investigated when firms exhibit high sensitivity to credit ratings. Credit rating data from December settlement companies, spanning the period from 2002 to 2019, excluding the financial industry, is employed. A total of 2,179 company-year observations are used, which include corporate patent data as a proxy for measuring innovation performance, to examine the relationship between credit ratings and innovation activities. Furthermore, the study analyzes how these relationships vary across high-tech and non-high-tech industries, as well as investment ratings and speculative ratings.
The empirical analysis reveals a significant positive relationship between the sensitivity of firms to credit ratings and their innovation activities. Specifically, firms that are more sensitive to credit rating downgrades show an increase in innovation activities, while no significant results are found for credit rating upgrades. This suggests that firms with a higher likelihood of credit rating downgrades are more likely to actively pursue innovation activities to maintain their current credit rating. Moreover, this asymmetric relationship between credit ratings and innovation is more pronounced in high-tech industries compared to non-high-tech industries, and in investment-rated firms compared to speculative-rated firms. Based on these empirical findings, this study provides important implications for stakeholders and financial market participants regarding the relationship between credit ratings and innovation.
A Study on the Internal Accounting Management System: Focusing on the Importance and Limitations of Research on Internal Accounting Personnel
Authors:   Academic Society of Global Business Administration, Kim Kyung Hye , Choi Kyong Soo
Published: May 2023

This study studies the internal accounting management system in depth. More specifically, we intend to present meaningful research results by examining the importance of research related to internal accounting personnel and considering the limitations of the relevant research.
Previous studies on internal accounting personnel are important in two aspects. First, they have inherent importance in the conceptual aspect. Second, in the empirical aspect, the uniqueness of the data and results generates the importance.
On the other hand, existing theoretical/empirical studies on internal accounting personnel have two limitations. First, they have limitations regarding the measurement issues. Second, they show various limitations regarding disclosed data.
The results of this study are meaningful in two aspects. First, we examine several issues about internal accounting management system critically by focusing on the personnel in charge of internal accounting. In particular, investigating the limitations of previous studies on internal accounting personnel from multiple angles is expected to provide useful implications for follow-up studies, information users, and policy authorities.
A Study on the Applicability of eXplainable Artificial Intelligence(XAI) Methodology by Industrial District
Authors:   Academic Society of Global Business Administration, Bae Jae Kwon
Published: May 2023

The learning performance of artificial intelligence (AI) technologies such as machine learning and deep learning is approaching or surpassing that of humans, and humans are gaining new insights through hidden patterns and rules discovered by AI, but their delivery and explanatory power is in short supply. As the use of AI technology expands by industry, values such as transparency, fairness, and accountability are continuously required in addition to accuracy. Accordingly, the demand and necessity for eXplainable Artificial Intelligence (XAI) has recently been emphasized. XAI is an analysis model, process, and service for determining the reliability of AI results by explaining what the reason is if there is an error in the output produced by the AI model. This study reviewed SHAP, LIME, and LRP, which are XAI methodologies, and explored the applicability of these methodologies to each industry. In the financial field, algorithms such as SHAP, LIME, and LRP can be applied to support credit rating prediction, loan decision-making, and investment decision-making, and to ensure their explainability and interpretability. This can increase fairness and reliability of AI results between financial consumers and financial institutions. In the defense and military fields, AI staff is being used as an auxiliary tool for key decision makers. If the explainability and interpretability of the results are guaranteed by applying XAI, the role of AI staff will change to active utilization. In the field of industrial accidents, SHAP can be used in a model that predicts industrial accidents to determine the degree of influence of variables that affect the occurrence of industrial accidents. As such, the XAI methodology can contribute to increasing the transparency and interpretability of models in various AI-based prediction models.
Genealogías de la Conservación de la Naturaleza. Procesos de institucionalización de las Áreas Protegidas
Authors: Santamarina Campos Beatriz , Vicente Rabanaque Teresa , Cortés-Vázquez José A.
Published: May 2023

Este número especial responde a la necesidad de preguntarse cómo se construyó la red de Áreas Protegidas (AP)[1] en los distintos territorios de España, tras la arquitectura del Estado de autonomías aprobado por la Constitución de 1978. Diversos factores condicionaron el desarrollo de las políticas de conservación en cada una de las comunidades autónomas (CC.AA.). En este monográfico nos acercamos a tres de ellas –Andalucía, Catalunya y Comunitat Valenciana–, dibujando sus trayectorias y buscando una comparación con el propósito de alcanzar una mayor comprensión del presente.
Áreas protegidas en Cataluña (1970-1988): demandas sociales, conservación y ordenación del territorio
Authors: Gil-Farrero Judit
Published: May 2023

Este artículo tiene como objetivo describir y analizar las iniciativas, propuestas y políticas públicas en relación con las áreas protegidas y la ordenación del territorio desarrolladas en las últimas tres décadas del siglo XX en Cataluña. A través de entrevistas en profundidad y revisión de fuentes documentales, se examinan el marco legal y el sistema de áreas protegidas desplegados a lo largo de estos años por las distintas administraciones que intervinieron, teniendo en cuenta el contexto social y político en el que fueron apareciendo las distintas disposiciones legales. También se valora el papel que desempeñó la sociedad civil, con especial énfasis en el colectivo docente e investigador universitario.
El inicio de la conservación de Áreas Protegidas en la Comunitat Valenciana. La institucionalización de la protección como herramienta política
Authors: Ruiz Torres Miquel Angel , Santamarina Campos Beatriz , Campo Muñoz Ana
Published: May 2023

Desde mediados de la década de 1980 el primer gobierno de la Generalitat Valenciana inicio la declaración oficial de espacios protegidos en su territorio, mediante la creación de distintas figuras de protección. El proceso fue llevado a cabo de forma expeditiva desde la transferencia de competencias en materia de conservación de la naturaleza (1984) por parte del Estado español. Este desarrollo se ejecutó sin un marco legal autonómico apropiado, con movilizaciones sociales para la defensa del medio, con diversos grados de oposición local y con una creciente extensión de la urbanización de la costa. En un contexto de legitimación de fuerzas políticas democráticas y de transformación de las nociones de conservación de los ecosistemas, irrumpe la idea de la protección de urgencia, pero sin los instrumentos de gestión y recursos suficientes. En este artículo se presentan las claves para entender el incipiente proceso de institucionalización de las áreas protegidas en la Comunitat Valenciana (España) a través de entrevistas realizadas a los principales cargos políticos y gestores de aquella época.
Detection of Rubidium and Samarium in the Atmosphere of the Ultrahot Jupiter MASCARA-4b
Authors: Jiang Zewen , Wang Wei , Zhao Gang , Zhai Meng , Shi Yaqing , Liu Yujuan , Zhao Jingkun , Chen Yuqin
Published: May 2023

Ultrahot Jupiters (UHJs) possess the most extreme environments among various types of exoplanets, making them ideal laboratories to study the chemical composition and kinetics properties of exoplanet atmosphere with high-resolution spectroscopy. It has the advantage of resolving the tiny Doppler shift and weak signal from exoplanet atmosphere and has helped to detect dozens of heavy elements in UHJs including KELT-9b, WASP-76b, and WASP-121b. MASCARA-4b is a 2.8 days UHJ with an equilibrium temperature of ∼2250 K, which is expected to contain heavy elements detectable with the Very Large Telescope (VLT). In this letter, we present a survey of atoms/ions in the atmosphere of the MASCARA-4b, using the two VLT/ESPRESSO transits data. Cross-correlation analyses are performed on the obtained transmission spectra at each exposure with the template spectra generated by petitRADTRANS for atoms/ions from element Li to U. We confirm the previous detection of Mg, Ca, Cr, and Fe, and report the detection of Rb, Sm, Ti+, and Ba+ with peak signal-to-noise ratios (S/Ns) > 5. We report a tentative detection of Sc+, with peak S/Ns ∼ 6 but deviating from the estimated position. The most interesting discovery is the first-time detection of elements Rb and Sm in an exoplanet. Rb is an alkaline element like Na and K, while Sm is the first lanthanide series element and is by far the heaviest one detected in exoplanets. Detailed modeling and acquiring more data are required to yield abundance ratios of the heavy elements and to understand better the common presence of them in UHJ’s atmospheres.
Unveiling Properties of the Nonthermal X-Ray Production in the Gamma-Ray Binary LS 5039 Using the Long-term Pattern of Its Fast X-Ray Variability
Authors: Yoneda Hiroki , Bosch-Ramon Valenti , Enoto Teruaki , Khangulyan Dmitry , Ray Paul S. , Strohmayer Tod , Tamagawa Toru , Wadiasingh Zorawar
Published: May 2023

Gamma-ray binary systems, a subclass of high-mass X-ray binaries, show nonthermal emissions from radio to TeV. While efficient electron acceleration is considered to take place in them, the nature of the acceleration mechanism and the physical environments in these systems have been a long-standing question. In this work, we report on long-term recurrent patterns in the short-term variability of the soft X-ray emission of LS 5039, one of the brightest gamma-ray binary systems. The Neutron star Interior Composition Explorer (NICER) observed LS 5039 four times from 2018 to 2021. By comparing them with the previous Suzaku and NuSTAR long-exposure observations, we studied the long-term evolution of the orbital light curve in the soft X-ray band. Although the observations by NICER and Suzaku are separated by ∼14 yr, i.e., more than 103 orbits, the orbital light curves show remarkable consistency after calculating their running averages with a window width ≳70 ks. Furthermore, all of the light curves show short-term variability with a timescale of ∼10 ks. Since the column density did not vary when the flux changed abruptly, such a short-term variability seems to be an intrinsic feature of the X-ray emission. We propose that the short-term variability is caused by clumps (or inhomogeneities) of the companion star wind impacting the X-ray production site. The observed timescale matches well with the lifetime of the clumps interacting with the pulsar wind and the dynamical timescale of the relativistic intrabinary shock in the pulsar wind scenario.
Is adherence to national guidelines for parenteral empiric antibiotic therapy effective? Experience from a Sri Lankan center
Authors: Chathuranga Gayashan , Dissanayake Thushari , Fernando Neluka , Wanigatunge Chandanie Amila
Published: May 2023

Introduction: Guidelines for the selection of empirical antibiotics have been developed to improve patient outcomes and reduce unnecessary antibiotic use. We assessed the extent of adherence to the national guidelines for the selection of parenteral empirical antibiotics for three selected infections at a tertiary care center.
Methodology: A prospective cross-sectional study was conducted in medical and surgical wards of a tertiary care hospital in Sri Lanka. Adult patients with a positive culture for a lower respiratory tract infection (LRTI), skin and soft tissue infection (SSTI), or urinary tract infection (UTI) and who were prescribed parenteral empirical antibiotic therapy by the attending physician were included. Bacteria were identified and antibiotic susceptibility was determined by standard microbiological methods. Adherence to the guidelines was defined as prescribing the empiric antibiotic concordant with the national guidelines on the empirical use of antibiotics.
Results: A total of 160 bacterial isolates were obtained from 158 patients with positive cultures, the majority were from UTIs (n = 56). The selection of empirical antibiotics was concordant with the national guidelines in 92.4% of patients and 29.5% of the bacterial isolates obtained from these patients were resistant to the prescribed empiric antibiotic. Only 47.5% (76/160) of the bacterial isolates were sensitive to the empiric antibiotic and therefore can be considered an appropriate antibiotic prescription.
Conclusions: Empirical antibiotic guidelines should be updated based on the latest surveillance data and information on prevailing bacterial spectra. Antibiotic prescribing patterns and guideline concordance should be periodically evaluated to ensure whether antimicrobial stewardship programs are moving in the right direction.
Pediatric deep venous thrombosis associated with Staphylococcus aureus osteomyelitis
Authors: Liu Linlin , Guo Lingyun , Wang Zhuangzhuang , Wang Qiang , Zeng Jinjin , Chen Tianming , Liu Gang
Published: May 2023

Introduction: Our objective was to evaluate clinical features of children with deep venous thrombosis (DVT) and acute hematogenous osteomyelitis (AHO) caused by Staphylococcus aureus.
Methodology: We analyzed 4 years of medical records of patients with AHO and DVT caused by Staphylococcus aureus (S. aureus) and compared clinical and biochemical characteristics of AHO with and without DVT, as well as patients whose DVT dissolved in ≥ 3 weeks.
Results: DVT was found in 19/87 AHO individuals (22%). The median age was 9 years (range: 0.5-15 years). 74% (14/19) patients were boys. Methicillin-susceptible Staphylococcus aureus (MSSA) was present in 58% (11/19) cases. The femoral vein and common femoral vein were the two most damaged veins (9 cases each). Anticoagulation therapy with low molecular weight heparin was given to 18 (95%) patients. Within 3 weeks of anticoagulation, 7/13 (54%) with available data had completely resolved DVT. There was no rehospitalization due to bleeding or recurrent DVT. Patients with DVT were found to be older and had increased levels of C-reactive protein, procalcitonin, D-dimer, positive blood culture, incidence of intensive care unit admission, multifocal rate, and length of hospital stay. We did not find clinical difference between patients whose DVT dissolved within 3 weeks and those with > 3 weeks.
Conclusions: Over 20% of patients with S. aureus AHO developed DVT. MSSA accounted for more than half of the cases. DVT was completely resolved in more than half of the cases after 3 weeks of anticoagulant medication, with no sequelae.
Predictors of mortality in hemodialysis patients with COVID-19: A single-center experience
Authors: Rista Elvana , Dervishi Dorina , Cadri Vilma , Akshija Ilir , Saliaj Kristi , Bino Silvia , Puca Edmond , Harxhi Arjan
Published: May 2023

Introduction: The COVID-19 pandemic has disproportionately affected patients with preexisting comorbidities, particularly dialysis patients. The aim of this study was to determine predictors of mortality in this population.
Methodology: We conducted an observational, retrospective, cohort study collecting data from pre and post-vaccine from the electronic medical records of a single dialysis center at Hygeia International Hospital Tirana, Albania.
Results: Of 170 dialysis patients, 52 were diagnosed with COVID-19. The prevalence of COVID-19 infection in our study was 30.5%. The mean age was 61.5 ± 12.3 years and 65.4% were men. The mortality rate in our cohort was 19.2%. Mortality rates were higher in patients with diabetic nephropathy (p < 0.04) and peripheral vascular disease (p < 0.01). Elevated C- reactive protein (CRP) (p < 0.018), high red blood cell distribution width (RDW) (p < 0.03), and low lymphocyte and eosinophil counts, were found to be risk factors for severe COVID-19 disease. ROC analysis identified lymphopenia and eosinopenia as the strongest predictors of mortality. After the vaccine administration, the mortality rate in the vaccinated population was 8%, in contrast to the 66.7% mortality rate that was found in the unvaccinated group (p < 0.001).
Conclusions: Our study revealed that risk factors for the development of severe COVID-19 infection were RDW, low lymphocyte and eosinophil counts, elevated levels of CRP. Lymphopenia and eosinopenia were determined as the most important predictors of mortality, in our cohort. Mortality was notably lower among vaccinated patients.
Competency of Tuberculosis Instructor after Training with Citizenship Behavior-Based Organizational Training Management
Authors: Sianturi Efendi , Situmorang Benyamin , Simaremare Aman
Published: May 2023

INTRODUCTION: The success of the health extension program depends on the performance of health extension workers in carrying out their roles and functions professionally. The education and training they have attended influence the professionalism, competence, and performance of tuberculosis instructors. AIM: This study aims to analyze the competence of the tuberculosis instructor after training by the Organizational Citizenship Behavior-based training management model. METHODS: A prospective cross-sectional interventional study with baseline and repeat surveys were conducted to evaluate the effect of organizational citizenship behavior-based training management. Education and training of public health instructors are carried out for three days. The participants were 60 people from 30 community health centers selected purposively as an intervention and control. RESULTS: Independent t-test statistical test was shown that the management of education and training based on Organizational Citizenship Behavior was effective in increasing the competence of tuberculosis instructors (p-value = 0.001). CONCLUSION: Organizational Citizenship Behavior is a description of the positive behavior of employees, namely their behavior will exceed the competence of the organization. Management of training based on Organizational Citizenship Behavior is an alternative to conducting training as a way to develop the quality and skills of tuberculosis instructors and human resources in health institutions, in general, more effectively and efficiently.
The Effectiveness of Video Observed Therapy towards Compliance with Drug throughout Tuberculosis Patients
Authors: Fuadiati Lie Liana , Sukartini Tintin , Makhfudli Makhfudli
Published: May 2023

BACKGROUND: Treatment of tuberculosis is carried out every day in the long-term, causing boredom to take medication and reducing medication adherence. Taking medication that is not routine causes drug resistance which can cause tuberculosis treatment to take longer.

AIM: This study aims to review the effect of the application of drug-taking supervisors on drug adherence in tuberculosis patients.

METHODS: The research design uses the preferred reporting items for systemic review and meta-analysis Guidelines with an online literature search strategy using the Google chrome search engine Scopus, Science Direct, PubMed, CINAHL, and Proquest. The year of the literature source was taken from 2018 to 2022. From the articles searched, five articles were obtained and reviewed.

RESULTS: The results of a review of five articles showed that video observed therapy (VOT) technology was needed to improve medication adherence in tuberculosis patients.

CONCLUSION: This review shows the role of VOT technology to improve medication adherence in tuberculosis patients.
Factors Associated with Attitudes toward Scientific Research Vietnam Nursing Students: A Cross-sectional Study
Authors: Nguyen Tuan Van , Nguyen Huynh Xuan Thi , Nguyen Hanh Thi , Dao Linh Yen Thi , Nguyen Nguyen Thu Thi , Pham Kieu Be Thi , Duong Trang Thuy Thi , Nguyen Thuy Hong , Wantonoro Wantonoro
Published: May 2023

Background: Nursing students do scientific research at the university level not only contributing to the development of the nursing profession but also helping themselves to practice more useful skills for future work. A positive attitude toward scientific research has been shown to motivate students to practice research. Objective: to assess attitudes toward scientific research and explore associated factors of nursing students in Vietnam. Methods: A cross-sectional study design was adopted and conducted on 238 nursing undergraduate students. Study samples were collected from October to November 2021 through a face-to-face meeting with study subjects and an accidental sampling technique. The attitudes Toward Research Scale was used in this study. Results: The study showed that 76.1% of nursing students had a positive attitude toward scientific research. Through simple linear regression analysis, it showed that having been or participating in scientific research projects (p=0.019), scientific research activities (p=0.028); intending to pursue a postgraduate degree (p=0.016); being introduced/invited to participate in scientific research projects (p=0.021) and having contact with people who can guide scientific research (p=0.033) was the factors that affect nursing students' attitudes toward scientific research. Conclusions: Many associated factors influence the attitude toward scientific research of nursing students. Further effective interventions are needed to address this issue
PedSQL™ Family Impact Module as an Instrument foe Quality of Life Assessment (PedsQL™) in Children with Chronic Postsurgical Pain
Authors: Semkovych Yaroslav , Dmytriiev Dmytro , Dobrovanov Oleksandr
Published: May 2023

BACKGROUND: The concept of quality of life (QoL) is today an integral part of the health-care system and clinical, medical, and social research. Untreated chronic pain in children increases the risk of developing mental disorders later in life. The pediatric QoL inventory 3.0 (PedsQL™) is one of the most valid and widely used tools for assessing pediatric QoL. AIM: The study was to assess QoL in children with chronic postsurgical pain 7 days, 3 months, and 6 months after surgery with different analgesic techniques by means of the PedsQL™ 3.0 Family Impact Module questionnaires. METHODS: Following the inclusion and exclusion criteria, a total of 80 children undergoing treatment at the surgical department of a Communal Non-Profit Enterprise “Ivano-Frankivsk Regional Children’s Clinical Hospital of Ivano-Frankivsk Regional Council” were enrolled in the study. Among them, 60 children underwent anterior abdominal wall surgery with various types of anesthetic techniques. The patients were asked to fill in the questionnaires repeatedly 3 and 6 months after hospital discharge. RESULTS: QoL in patients with chronic pain syndrome reduced significantly (p < 0.001) on the scales of physical functioning, emotional functioning, social functioning, cognitive functioning, communication, worry, daily activities, family relationships, as well as pediatric QoL summary score, parent QoL summary score, and family functioning summary score 3 and 6 months after surgery with conventional analgesic techniques. CONCLUSIONS: Chronic pain syndrome reduces QoL in children aged 7–18 years after anterior abdominal wall surgery by reducing their physical, emotional, social, and cognitive functioning. The myofascial block in conjunction with general anesthesia accelerates patient’s recovery, relieves pain, and reduces emotional stress.
Assessment of Aggressive Behavior, Traffic Safety Rules and Regulation of Female Drivers in the Capital City Riyadh, Saudi Arabia: A Comprehensive Study
Authors: Shariq Ali , Rasheed Zafar , Alharbi Abdulaziz M. , Wahaq Abdulrahman AAB. , Alharbi Fawaz S. , Alsolai Ahmed , Alothaim Yunes A. , Alsughayer Hasan HH. , Alamer Hamad , Alnassar Mohammed A. , Al-Enez Thamer SS. , Al Abdulmonem Waleed
Published: May 2023

BACKGROUND: Road Traffic Injuries (RTIs) is a vital concern that affect mutually both developed and undeveloped countries. In Saudi Arabia the death rate from traffic accidents is approximately 28.8 per 100,000 people. In the year 2018, the Kingdom of Saudi Arabia finally set an end to its legal ban on car driving for women, providing the way for millions of new drivers to steer across the country. Conversely, gender has a statistically momentous impact on driving behavior.
AIM: In this study we studied about the principal attitudes and behaviors of female drivers in Capital City Riyadh.
METHODS: This is a cross-sectional study in which we analyzed female’s behavior which they are living in Riyadh City using the “Dulla index” instrument to identify whether aggressive driving behavior is expected in females in Riyadh. 
RESULTS: Using DDDI, we found that aggressive and dangerous driving behavior is not common among female drivers in Riyadh City. However, aggressive behavior was found three times more among employees when they drive than students, as well as participants with the educational level of (diploma/bachelor), (Singles/Divorced/widows), and those who (employees) were more likely associated with the behaviors of risky driving than their counterpart.
 CONCLUSION: This study revealed that the women who reside in Riyadh city are well-educated about the traffic laws, and the rate of aggressive, dangerous driving behavior was uncommon among them. Further studies are required to augment knowledge and condense the hazardous driving behaviors in Saudi Arabia.
Factors Influencing COVID-19 Prevention Behavior: A Community-based Cross-sectional Study
Authors: Ernawaty Ernawaty , Dherindri Nabilla Belqys
Published: May 2023

BACKGROUND: The coronavirus disease-19 (COVID-19) pandemic in Indonesia forced the local community to live in a New Normal era with several rules and health protocols that control the community’s behavior on COVID-19 prevention and control. This policy enabled several districts in Indonesia to reopen their travel and tourism sectors including Banyuwangi. Although the Banyuwangi Government already taking action in the implementation of the New Normal in the travel and tourism sectors, the COVID-19 trend in Banyuwangi was significantly increased. This suggest that the violation to health protocols and new normal policy could exist in Banyuwangi.

AIM: This study aimed to identify the predisposition, enabling, and reinforcing factors in the COVID-19 prevention and control behavior and analyze factors that associated with the COVID-19 prevention and control behavior in Banyuwangi district local community.

MATERIALS AND METHODS: A cross-sectional study design was conducted. The data were obtained through online survey that was disseminated to Banyuwangi district local community. A descriptive, linear regression, and logistic regression analysis was applied.

RESULTS: The knowledge and attitude on COVID-19 preventive behavior of the 352 respondents in this study were poor and adequate, respectively. The predisposition factors associated with the COVID-19 prevention and control behavior in this study were sex (p = 0.005), level of education (p = 0.028), knowledge (p = 0.015), and attitude (p ≤ 0.01). The reinforcing factor associated with the behavior was support from family (p ≤ 0.01), key opinion leader (p = 0.02), and health worker (p = 0.05). Health facility and infrastructure were also found to be associated with the behavior (p ≤ 0.01).

CONCLUSION: Several approaches and commitments from the policymakers to strengthen those factors are required to improve the behavior on COVID-19 prevention and control.
Consumer Legal Protection for Patients and the Quality of Health Services in Hospitals
Authors: Prastyanti Rina Arum , Santoso Aris Prio Agus , Saidah Siwi Ellis , Ngestiningrum Ayesha Hendriana , Budiono Arief
Published: May 2023

BACKGROUND: Health development is part of Indonesia’s national development. It is implemented by creating a social security system run by the Social Security Administrator for Health (Badan Penyelenggara Jaminan Sosial Kesehatan/BPJS Health) based on Law No. 24 of 2011.

AIM: This study analyzes the legal protection for BPJS health participants who are hospital inpatients. It also discusses their rights and obligations that are yet unfulfilled.

METHODS: This research uses the juridical doctrinal or normative method. This is descriptive research with a qualitative approach.

RESULTS: As patients, BPJS health participants’ rights are legally protected by Law No. 36 of 2009 on Health and Law No. 44 of 2009 on Hospitals. Unfortunately, some participants often experience problems when they require hospitalization. For instance, there is usually a lack of information on the provision of treatment rooms. Another issue is that the BPJS patients often only obtain a 3-day hospitalization facility as the fee allocation from BPJS health has run out.

CONCLUSION: Thus, it is concluded that there is adequate legal protection for BPJS health patients who are hospitalized both as consumers and as BPJS health participants. However, there are still issues with its application. The participants who feel harmed by the treatment may file a lawsuit on consumer protection concerning the inadequate services or a lawsuit on malpractice if there are violations.
Another crack in the Dark Taxa wall: a custom DNA barcoding protocol for the species-rich and common Eurytomidae (Hymenoptera, Chalcidoidea)
Authors: Jafari Samin , Müller Björn , Rulik Björn , Rduch Vera , S. Peters Ralph
Published: May 2023

DNA barcodes are a great tool for accelerated species identification and for complementing species delimitation. Furthermore, DNA barcode reference libraries are the decisive backbone feature for any metabarcoding study in biodiversity monitoring, conservation or ecology. However, in some taxa, DNA barcodes cannot be generated with published primers at a satisfying success rate and these groups will consequently be largely missing from any barcoding-based species list. Here, we provide a custom DNA barcoding forward primer for the Eurytomidae (Hymenoptera, Chalcidoidea), elevating the success rate of high-quality DNA barcodes from 33% to 88%. Eurytomidae is a severely understudied, taxonomically challenging, species-rich group of primarily parasitoid wasps. High species numbers, diverse ecological roles and widespread and common presence identify Eurytomidae as one of many crucial families in terrestrial ecosystems. It is now possible to include Eurytomidae when studying and monitoring the terrestrial fauna, highlighting that barcoding-based approaches will need to routinely use different primers to avoid biases in their data and inferences. The new DNA barcoding protocol is also a prerequisite for our integrative taxonomy study of the group, aiming at delimiting and characterising Central European species and filling the GBOL (German Barcode Of Life) DNA barcode reference library with species-named and voucher-linked sequences.
Morphology, taxonomy, biogeography and ecology of Micrasterias foliacea Bailey ex Ralfs (Desmidiales, Zygnematophyceae)
Authors: Levanets Anatoliy , Janse van Vuuren Sanet
Published: May 2023

Micrasterias foliacea(Desmidiales, Zygnematophyceae) is an interesting desmid species as its filamentous life form is quite different from all other species within the genus. Due to the large size of the filaments and cells, accurate species identification is easy. After its original description from Rhode Island (USA) it was recorded from five continents, but no record could be found of its presence in Europe. In this paper a review of the worldwide distribution ofM. foliacea(Desmidiales, Zygnematophyceae) is presented, together with notes on the species’ ecology. In addition to its currently known geographical distribution, the paper also records the species’ presence at two new locations in southern Africa, namely Botswana (Okavango River) and Mozambique (Palma, Cabo Delgado). The paper presents a discussion of taxonomical levels of intraspecific taxa, based on morphological characteristics. It is proposed that the taxonomical status of M. foliacea Bailey ex Ralfs f. nodosa should be raised to the variety, as its nodular cell wall thickenings are unique morphological features.
SIGEM : analyse de la procédure d’affectation dans les grandes écoles de management
Authors: Iehlé Vincent , Jacqmin Julien
Published: May 2023

La procédure centralisée du SIGEM est en charge de l’affectation des candidats reçus aux concours des grandes écoles de management en France. Elle est basée sur l’utilisation d’un algorithme connu qui correspond à la version « écoles » de l’algorithme de Gale et Shapley [1962]. Les résultats théoriques des modèles d’appariement, liés à cet algorithme, permettent d’identifier des propriétés fondamentales satisfaites par la procédure. Certains particularismes de l’environnement du SIGEM qui génèrent des comportements stratégiques de la part des participants sont étudiés. Nous montrons comment le résultat de la procédure est finalement utilisé pour générer un classement des écoles. Les implications de cette hiérarchisation commune des écoles, propre au SIGEM, sont également évaluées. Classification JEL  : C78, D78, I23.