bluuebunny/crossref_metadata_2025 huggingface dataset:
The Relationship between Fast Food, Sleep Patterns, and Facial Hygiene with the Severity of Acne Vulgaris
Authors: Putri Winawati Eka , Hilda Naila Farah , Kusumah Fiona Restu , Yulian Ardhien Alif , Ulfa Maria , Widyaswari Meidyta Sinantryana , Nadya Niken Adiba
Published: December 2024

Introduction:

Acne vulgaris (AV) is a chronic inflammatory disease that affects several parts of the body, such as hair follicles, the face, and the neck. AV often occurs in adolescents due to increased sebum production, hyperkeratinization of pilosebaceous follicles, and inflammation. AV is a multifactorial inflammation that can be triggered by several factors, such as frequent fast-food consumption, poor facial hygiene, and poor sleep habit. This research was performed to examine the relationship between fast-food consumption, facial hygiene, and sleep patterns with AV severity among students of Universitas Nahdlatul Ulama Surabaya (UNUSA).

Methods:

An analytic observational with a cross-sectional approach was conducted on 60 respondents. The data were collected using the Dermatology Life Quality Index, based on which respondents’ quality of life related to skin problems was examined. Meanwhile, the Food Frequency Questionnaire was distributed to assess food consumption, and a questionnaire measuring facial hygiene was used to assess respondents’ face condition. Furthermore, respondents’ quality of sleep was measured using the Pittsburgh Sleep Quality Index. The aforementioned data then underwent univariate and bivariate analysis.

Results:

The results showed that the most consumed types of fast food by UNUSA students were fried chicken, and while the severity of AV was considered low. Most of the students have poor sleep quality. A significant association was found between the frequency of fast-food consumption, facial hygiene (P = 0.041), and sleep patterns (P = 0.043) with the severity of AV.

Conclusions:

The frequency of fast-food consumption, facial hygiene, and sleep patterns are significantly associated with the severity of AV among UNUSA students.
Correlation between P-glycoprotein and CD34 Expressions in Leukemic Cells from De novo Acute Myeloid Leukemia
Authors: Indrasari Yulia Nadar , Hernaningsih Yetti , Aryati Aryati , Bintoro Siprianus Ugroseno Yudho , Atika Atika , Hassan Rosline
Published: December 2024

Introduction:

Acute myeloid leukemia (AML) is a clonal cancer that develops from myeloid progenitors. P-glycoprotein (Pgp) is the membrane transporter encoded by the multidrug resistance (MDR1) gene, which is responsible for the efflux of several chemotherapeutic drugs for the treatment of AML. Pgp’s physiological role in normal cells is unknown. This contrasts with the lack of clarity on Pgp’s activity as an efflux pump in neoplastic or cancer cells. The association between Pgp and CD34 expression in adult patients with de novo AML was investigated in this study.

Methods:

Thirty participants were enrolled between November 2022 and April 2023. Immunophenotyping, Pgp percentage, and CD34 expression examinations using bone marrow aspirate blood were performed using immunoflowcytometry. The analysis of the correlation test was performed by Spearman correlation.

Results:

Patients with de novo AML had a median age of 42.5 years. The bone marrow aspiration results of adult patients with AML reveal the following distribution according to the French–American–British classification: 30% of patients have AML M1, 30% have AML M2, 13.33% have AML M3, 3.33% have AML M4, 16.66% have AML M5, and 6.66% have AML M7. There was no statistical correlation between Pgp and CD34 (P = 0.063), neither Pgp and leukocyte count (P = 0.442).

Conclusions:

Although no correlation between Pgp with CD34 or leukocyte count, it is necessary to consider the role of other members of the ABC transporter superfamily to further examine its relationship with CD34.
Community-acquired lower respiratory tract infection due to Serratia rubidaea: A rare and opportunistic pathogen
Authors: Singh Peetam , Pandey Anita
Published: December 2024

The genus Serratia belongs to the order enterobacterales consisting of Serratia marcescens as the most common species of clinical importance and non-S. marcescens species including Serratia fonticola, Serratia odorifera, Serratia plymuthica, Serratia liquefaciens, and Serratia rubidaea. Most of these non-S. marcescens species are usually considered as nonpathogenic and rarely reported to be associated with various clinical conditions in humans. S. rubidaea is rarely described as member of the genus Serratia which is naturally found in the environment including soil and water. S. rubidaea has been reported as human pathogen, and its isolation from clinical specimens is rare. S. rubidaea has been reported as an opportunistic pathogen affecting immunocompromised individuals. Only few case reports are available documenting clinical significance of S. rubidaea causing various invasive and life-threatening manifestations. We report four cases of community-acquired lower respiratory tract infection caused by S. rubidaea in immunocompromised patients from a tertiary care teaching institute from Uttar Pradesh, India.
Radiographic Changes and Clinical Outcomes Associated with Two Different Press-Fit Humeral Stems in Primary Reverse Shoulder Arthroplasty
Authors: Catma MF , Adıgüzel İF , Yildiz SY
Published: December 2024

Background:

Reverse shoulder arthroplasty (RSA) is used commonly for a wide range of indications. The complications after the total shoulder replacements have been reported to be related with the prosthesis design. The type of the humeral stem is a consideration to reduce complication. Radiographic changes are seen at a high rate with new-generation press-fit stems.

Aim:

This study aims to reduce proximal humeral bone loss after RSA could have been achieved with adjustable humeral stem when compared with monoblock stem.

Methods:

A retrospective analysis was made of 52 patients treated with RSA using a press-fit humeral stem prosthesis. The patients were separated into two groups according to the type of humeral stem. The first group included 26 patients (18 females, 8 males) who underwent RSA using adjustable humeral stem. The second group included of 26 patients (17 females, 9 males) for whom monoblock humeral stem was used. Clinical and radiological evaluations were made based on the information obtained at 1, 3, 6, 12, and 18 months postoperatively. The follow-up duration was at least 18 months.

Results:

There was no statistical difference between the adjustable and monoblock groups in respect to gender, age, height, and weight. According to the functional measurements at the final follow-up, no statistically significant difference was determined between the groups with respect to the Constant, UCLA, Oxford, DASH, and VAS values. In terms of radiographic changes, both groups were seen to have been similarly affected. It was found that, irrespective of the stem type used, the humeral side radiographic adaptation was found to be high, which negatively affected the functional results (P < 0.05).

Conclusion:

The increased radiographic stress shielding adaptation leading to humeral osteolysis was found to have a negative effect on the functional results with the press-fit technique irrespective of stem design.
Treatment Outcome of Macular Hole Associated with Rhegmatogenous Retinal Detachment
Authors: Okonkwo ON , Akanbi T , Onwuegbuna AA
Published: December 2024

Background:

Macular holes are an infrequent association with rhegmatogenous retinal detachment, increasing the complexity of surgery and affecting outcome.

Aim:

To report the visual outcome, macular hole (MH) closure, and retinal reattachment rate after vitrectomy with silicone oil plus different MH closure techniques for MH associated with rhegmatogenous retinal detachment and to compare the visual outcome between the techniques.

Materials and Methods:

A retrospective, comparative study. Review of pre and postoperative Snellen best corrected visual acuity (BCVA) and the logarithm of minimum angle of resolution (LogMAR) conversion for nine eyes of 9 consecutively treated macular hole in rhegmatogenous retinal detachment patients. Pre and postoperative optical coherence tomography (OCT) macula scans and retinal reattachment three months post silicone oil removal were assessed.

Results:

Surgical techniques: Inverted internal limiting membrane flap (n = 4; 44.45%), internal limiting membrane (ILM) plug (n = 4; 44.45%), and autologous retinal transplant (n = 1; 11.1%). Outcome: Single-surgery retinal reattachment rate was 88.9% (8/9 eyes), and 100% with second surgery. Primary MH closure was 100%. One reopened MH with retinal re-detachment, post silicone oil removal, required additional surgery. The mean preoperative BCVA was 2.53 ± 0.93 LogMAR, and mean postoperative BCVA was 0.94 ± SD 0.43 LogMAR (P = 0.000). Mean change in Snellen line = 2.22 ± 1.72. The postoperative vision was the same as preoperative in 22.2% and improved in 77.8%. Mean postoperative vision for the inverted ILM flap group (n = 4) was 1.10 ± 0.62 LogMAR (P = 0.038), and for the ILM plug group (n = 4) 0.83 ± 0.23 LogMAR (P = 0.002). The surgical technique did not influence postoperative BCVA (P = 0.85). Only one eye had an outer retina on OCT evaluation. Complications were macular atrophy (55.6%), macular edema (44.4%), and epiretinal membrane (33.3%).

Conclusion:

Single-surgery retinal reattachment rate and macular hole closure using any of the techniques is high, and none showed superiority.
An In-vitro Evaluation of the Shear Bond Strength to Dentin and Microhardness of Different Restorative Materials Placed by Different Techniques
Authors: Nezir M , Özcan S
Published: December 2024

Background:

The mentioned advantages of bulk-fill composite resin and high-viscosity glass ionomer restorative materials have increased their use in restorative dentistry in recent years; accordingly, the bonding of these materials to dental tissues and their mechanical properties have become more important.

Aim:

This study aimed to evaluate the effects of different application methods on Vicker’s hardness and shear bond strength of three different restorative materials.

Methods:

In this in-vitro study; Teflon molds were used for the microhardness test. In the control group, reinforced high-viscosity glass ionomer, high-viscosity glass ionomer, and flowable bulk-fill composite resin were applied by the manufacturer’s instructions. In other groups, preheating, ultrasonic activation, and both preheating and ultrasonic activation were applied, respectively (n = 14). Microhardness values of the upper surfaces of the specimens were measured with Vicker’s hardness measuring device. For the shear bond strength test, 84 intact human molar teeth were used. The teeth were sectioned two in the mesiodistal direction (n = 14). The materials were applied to the dentin using the same placement protocols as those used in the hardness test. After the specimens were maintained at 37°C for 24 h, the shear bond strength test was performed using a universal test device.

Statistical Analysis Used:

The data were analyzed using SPSS 26.0 at a 95% confidence level. The Mann–Whitney test was also used for the statistical analysis of the data (P = 0.05).

Results:

Preheating the restorative materials significantly decreased the shear bond strength in the flowable bulk-fill composite resin group (11.77 ± 4.46 MPa) compared with that in the control group (12.14 ± 4.23 MPa) (P < 0.05) but significantly increased the shear bond strength in the reinforced high-viscosity glass ionomer group (3.91 ± 2.93 MPa) (P < 0.05).

Conclusions:

It can be concluded that preheating before application may increase the shear bond strength of reinforced high-viscosity glass ionomer.
Pattern of Medication Adherence, Spirituality and Viral Load amongst Adult Patients on Highly Active Antiretroviral Therapy in Rural Southwest Nigeria
Authors: Olanrewaju Moronkeji Temitope , Olanrewaju Olatutu Ololade , Ibrahim Azeez Oyemomi , Ipinnimo Tope Michael , Ajayi Paul Oladapo , Sito Oluwafunmilayo Kehinde
Published: December 2024

Introduction:

Previous studies have been conducted on medication adherence in Southwest Nigeria, but none of these has reported the relationship between highly active antiretroviral therapy (HAART) adherence, spirituality and viral load (VL) amongst people living with Human immunodeficiency virus (HIV)/AIDS, especially in rural settings of Southwestern Nigeria. This study assessed the pattern of medication adherence, spirituality and VL and ascertained the association of socio-demographics and spirituality on medication adherence amongst patients on HAART in rural Southwestern Nigeria.

Materials and Methods:

A hospital-based cross-sectional study involving 321 consented patients on HAART who were recruited by systematic sampling technique at the adult HIV clinic. Data were collected using an interviewer-administered questionnaire that assessed participants’ socio-demographic profiles, medication adherence and spirituality. Their blood samples were collected and their VLs were determined. The data were analysed using SPSS version 20. Logistic regression was done to identify the independent predictors of medication adherence.

Results:

The majority of the respondents reported a medium level of medication adherence (66.4%), a high level of spirituality (68.8%) and a low level of VL (67.3%). Amongst variables that had a statistically significant association with medication adherence were being educated, married, divorced, separated or widowed (P < 0.05). Furthermore, persons with high spirituality were 2.6 times more likely to be adherent to antiretroviral drugs when compared to persons with low spirituality (P < 0.05).

Conclusion:

It was shown that high spirituality is a positive predictor of medication adherence amongst patients on HAART. It, therefore, suggests that efforts deployed to improve the spirituality of these patients would most likely improve their medication adherence.
Phenotype and genetic spectrum of six Indian patients with bestrophinopathy
Authors: Shakeel Areeba , Bhatt Darshan M , Gopal Lingam , Raman Rajiv , Rao Chetan , Sripriya S. , Bhende Muna
Published: December 2024

The aim of this study is to describe genotype and phenotype of patients with bestrophinopathy. The case records were reviewed retrospectively, findings of multimodal imaging such as color fundus photograph, optical coherence tomography (OCT), fundus autofluorescence, electrophysiological, and genetic tests were noted. Twelve eyes of six patients from distinct Indian families with molecular diagnosis were enrolled. Exon 4 of BEST1 was mutated in 3 cases, while exons 2, 3, and 7 in others. Deletion is seen in Exon 7 and missense mutation in other exons. Sporadic autosomal dominant and recessive inheritance was observed in these families. Two patients had primary angle closure glaucoma with a history of consanguineous marriage and glaucoma in the family. Based on our findings, multifocal vitelliform subretinal deposits were the most common fundus finding in patients with autosomal recessive mutation while macular vitelliform lesion was seen with sporadic or autosomal dominant mutation; however, cosegregation analysis was not done. Baseline OCT showed macular and extramacular subretinal exudates, subretinal fluid, intraretinal cystic and schitic spaces, and thickened photoreceptors outer segment tips. Two patients developed abnormal vasculature and focal choroidal excavation in OCT. A severe reduction in the electro-oculogram Ardens ratio was noted while electroretinography was normal. Bestrophinopathy has a varied presentation with complex genotype-phenotype relationships. OCT is a noninvasive tool for monitoring and prognostication. Genetic testing of other family members should be facilitated.
Factores de participación y permanencia en las redes de profesores(as) de Inglés en la Región de Los Lagos: Desarrollo profesional docente en comunidades de aprendizaje
Authors: Ormeño Cárdenas Verónica , Llanquileo Aranda Elena , Sandoval Molina Soledad
Published: December 2024

Las Redes Docentes de Inglés (RDI) están compuestas por grupos de profesores que ejercen en establecimientos educacionales de distintas dependencias, quienes se reúnen regularmente para reflexionar e intercambiar experiencias que beneficien el aprendizaje de sus estudiantes. Esta investigación busca describir los factores que influyen en el interés de los miembros de dichas redes por participar y permanecer en estas iniciativas en la Región de Los Lagos. Se usó un enfoque mixto, cuyos datos cuantitativos fueron recolectados a través de una encuesta; en tanto los datos cualitativos se recogieron mediante un grupo focal. El análisis de los datos recolectados indica que el profesorado miembro de las RDI valora positivamente pertenecer a estas instancias, pues percibe contribuciones significativas en su quehacer docente, el fomento del trabajo colaborativo, las oportunidades de desarrollo profesional docente y el sentirse parte de una comunidad de aprendizaje con metas comunes.
Presentación de un proyecto de ingeniería cooperativa para transferir la institución didáctica del texto libre a la sala de clases
Authors: PROT Frédérique-Marie
Published: December 2024

Este estudio explora la ingeniería cooperativa aplicada a las prácticas de expresión escrita en las escuelas primarias francesas, centrándose específicamente en el método de «texto libre» del enfoque educativo Freinet. La ingeniería cooperativa, tal como la definen Sensevy y Bloor (2020), consiste en que educadores e investigadores diseñen, apliquen y perfeccionen en colaboración una secuencia didáctica. Este método no pretende innovar per se, sino tender puentes entre los modelos teóricos y la aplicación práctica en el aula, reconociendo las variaciones en las prácticas docentes. La investigación examina la transferibilidad del modelo de texto libre a entornos escolares convencionales para mejorar las habilidades de escritura de los alumnos y fomentar la colaboración entre ellos. Tras presentar el contexto y el modelo, el estudio describe el proceso colectivo cooperativo con profesores que buscan estrategias eficaces para la producción de textos. Además, aborda los retos a los que se enfrentan los profesores a la hora de adaptar sus métodos y replantearse la organización del aula. Mediante datos de observación, entrevistas y documentación multimedia, este estudio pretende establecer las condiciones para integrar con éxito el texto libre en las aulas tradicionales.
A $2$-complex with contracting non-positive immersions and positive maximal irreducible curvature
Authors: Blufstein Martín Axel , Minian Elías Gabriel
Published: December 2024

We prove that the

2

-complex associated to the presentation

\langle a,b \mid b,bab^{-1}a^{-2}\rangle

has contracting non-positive immersions and positive maximal irreducible curvature. This example shows that the contracting non-positive immersions property is not equivalent to the notion of non-positive irreducible curvature, answering a question raised by H. Wilton.
Feasibility study for weathered tufa stabilization using urease-producing bacteria isolated from Jiuzhaigou, Sichuan Province, China
Authors: Wang Siyi , Xie Hongguan , Wang Qi , Wu Shengjie , Li Shida , Gong Lian , Tong Jin , Xiao Weiyang , Lei Ningfei
Published: December 2024

Tufa, a loose and porous calcium carbonate deposit, is vulnerable to weathering, which can heighten the risk of geological hazards. This study investigated the potential of microbial-induced calcite precipitation (MICP) to stabilize weathered tufa by isolating urease-producing bacteria from Jiuzhaigou, Sichuan Province. Two strains with the highest urease activity, identified as Stenotrophomonas sp. (U1) and Lysinibacillus boronitolerans (U2), were selected for mixed cultures (Mc). The physiological characteristics and calcification capacity of the strains (U1, U2, and Mc), along with the mechanical properties of treated tufa columns (SCU-1, SCU-2, and SCM), were analyzed. The findings revealed that these strains effectively induced the formation of CaCO3. Mc demonstrated strong growth dynamics (OD600 = 3.9±0.1) and urease activity (865±17 U/ml), leading to enhanced CaCO3 production. Furthermore, MICP significantly improved the compressive and shear strength of the weathered tufa, with the SCM sample showing superior results compared to SCU-1 and SCU-2. Scanning electron microscopy (SEM) and X-ray diffraction (XRD) analyses confirmed that Mc produced a greater quantity of CaCO3 in the crystalline form of calcite. Overall, the results indicate that MICP represents a promising environmental protection technology that can effectively enhance the engineering properties of weathered tufa.
Fabrication of nitrogen-doped MXene composite electrode for efficient removal of sulfadiazine in homogeneous electro-Fenton system
Authors: Liu Huilai , Li Zhihao , Kong Defeng , Chen Xing
Published: December 2024

In this study, N-MXene-x (x denotes N loading) nanocomposites were successfully prepared by thermostatic ultrasonication and used as a cathode to construct a homogeneous electro-Fenton (EF) system for the degradation of sulphadiazine (SDZ). The characterization results that the electrocatalytic activity of the N-doped composites is significantly increased, which facilitates the two-electron oxygen reduction reaction (2e--ORR) and thus promotes the generation of hydrogen peroxide (H2O2) in the system. Experimental findings demonstrate that the N-MXene-3 cathode exhibits exceptional degradation performance for SDZ (97% removal in 60 min) during the homogeneous EF process. The catalytic oxidation mechanism of the N-MXene-3/EF system was explored by free radical quenching, electron paramagnetic resonance and frontier orbital theory studies, in which the main active substance for degrading SDZ was •OH. DFT calculations combined with the analysis of LC-MS results showed that SDZ was degraded mainly through amino oxidation, hydroxylation of heterocyclic roots, heterocyclic root ring opening, and C-S bond breaks. In addition, the N-MXene-3 cathode catalyst prepared in this study showed excellent stability through repeated experiments and also showed good performance in real water sample.
The Power of Faith and Social Media in Healing Women’s Mental Health – A Theological Study
Authors: Farid Ahmad Salman
Published: December 2024

This study investigates the profound interplay between social media engagement and spirituality in the journey of women overcoming anxiety and depression. With these pervasive mental health challenges affecting countless lives, understanding effective coping mechanisms becomes imperative. By intertwining the realms of digital connectivity and spiritual practices, this research explores how women navigate their mental health struggles, find support networks, and cultivate resilience. Drawing on a mixed-methods approach, this study delves into the experiences of a diverse cohort of women, capturing both quantitative data on social media usage patterns and qualitative insights into the significance of spirituality in their mental well-being. Through surveys, interviews, and content analysis, the multifaceted impact of social media platforms and spiritual beliefs on mental health outcomes is illuminated. The results reveal a complex landscape wherein social media serves as both a source of distress and a platform for connection and support. Moreover, spirituality emerges as a profound resource for coping, offering solace, hope, and a sense of purpose to women navigating the depths of anxiety and depression. Statistical analysis underscores the significant correlations between certain social media behaviors and mental health outcomes, while qualitative narratives enrich our understanding of the deeply personal and transformative role of spirituality in women's lives.
Mizah
Authors: Demir Murat
Published: December 2024

Gülmenin genel anlamda kimi zaman bir üstünlük, kimi zaman bir rahatlama veya kimi zaman uyuşmazlık kaynaklı olarak ortaya çıktığı ifade edilir. Bu üç sebebin her biri kendi adlarıyla birer kuramdır ve genel olarak da geleneksel gülme kuramları olarak anılırlar. Ancak bu üçünün dışında farklı mizah veya gülme teorileri olmasına rağmen bazı düşünürler bu farklı teorilerin de geleneksel kuramlardan türetildiğini ifade eder. Örneğin; çatışma teorisi, kararsızlık teorisi, yatkınlık teorisi, ustalık teorisi, Gestalt teorisi, Piagetçi teori ve konfigürasyon teorisi gibi teoriler uyuşmazlık kuramının varyasyonları olarak kabul edilir. Bununla birlikte, “Neden güleriz?” sorusunun cevabı aslında geleneksel kuramlardan daha karmaşık bir görünüm de sergilemektedir. Örneğin gülmemizin sebepleri toplumsal koşullar tarafından, politika tarafından belirlenebilir ve buna göre de farklı tarihsel/toplumsal koşullar altında farklı görünümler sergileyebilir. Eagleton da Mizah isimli eserinde yukarıda bahsi geçen konulara yer verir ve bunu felsefenin yanında politik ve tarihi yönlerine değinerek yapar. Ancak bunun yanında söz konusu alanların dışında farklı alanlardan bilim insanlarının fikirlerinden söz eder. Bu bağlamda, Eagleton’ın mizah hakkındaki düşünceleri bu çalışmanın konusunu oluşturmaktadır.
La machine à lire plurilingue : un outil numérique pour s’entrainer à lire en français langue seconde, en classe et à la maison
Authors: Perego Christine
Published: December 2024

L’article présente la mise en œuvre expérimentale d’un outil pédagogique numérique provisoirement nommé « la machine à lire plurilingue » dans des classes accueillant des enfants migrant·e·s plurilingues. L’analyse croise des observations de classes et des entretiens avec des enseignant·e·s et des parents.
The Role of Parental Language Profile and Home Linguistic Environment in Shaping Teenagers' Multilingual Identity
Authors: Hosseini Mona , Haukås Åsta
Published: December 2024

In the multilingual context of Norway, language policy at the macro level supports the development of multilingualism. At the meso level, parental language beliefs and ideologies and language practices in interactions among family members potentially play a critical role in learners’ experience of learning different languages and their multilingual identity. Drawing on Sims et al. (2016) and Spolsky (2012), this qualitative case study investigated parental language profiles, parents’ language ideologies and reported practices at home, and the potential impact these have on their children’s language choices, attitudes toward learning languages and the development of multilingual identity. The data were collected through an adapted version of the Ungspråk questionnaire (Haukås et al., 2021) from teenagers and interviews with parents and teenagers in three families with and without immigration backgrounds in Norway. We first analyzed the data using thematic analysis (Braun & Clarke 2006). Thereafter, the analysis was shared with the families to confirm the researchers’ understanding and acknowledge participants’ rights and voices. The findings of the study suggest that parental language profiles, their language beliefs, and home linguistic environment likely have a direct impact on teenagers’ language learning experience, views on multilingualism, and multilingual identities.
Towards language-sensitive teacher education: Developing a teacher competence taxonomy for the language dimension in languages and other subjects
Authors: Bleichenbacher Lukas , Schröder-Sura Anna
Published: December 2024

One of the aims of teacher education is to contribute to continuity in plurilingual, intercultural, and language-sensitive education, across subjects and educational levels. In this paper, we present selected results of two European projects that support this aim. The article outlines the background and potential of a taxonomy of teacher competences that exemplifies dimensions of language-related teacher competence shared by teachers of languages and other subjects. The dimensions include descriptors for teaching competences proper, for collaboration with other teachers and stakeholders, and for teacher development. Furthermore, a dimension containing competences related to the analysis of languages, discourse and cultures reframes aspects of language teachers’ content knowledge as a competence domain that is relevant, albeit to varying degrees, for all teachers. Two transversal dimensions, which contain teachers’ language and digital competences, an overview of teachers’ values and principles, and an account of professional learning opportunities complete the taxonomy.
Home-school relationship in the context of reception of newly arrived emergent bilingual pupils. A comparative and exploratory study between Hamburg (Germany) and Franche-Comté (France).
Authors: Krüger Ann-Birte , Melo-Pfeifer Silvia
Published: December 2024

This Franco-German exploratory and comparative study, rooted in the tradition of interdisciplinary qualitative empirical research (at the crossroads of sociology, language sciences and education sciences), aims at analysing and questioning the representations of the different actors concerning the reception of newly arrived allophone pupils and the home-school relationship in Germany (Gomolla 2009) and France (Asdih 2012, Lasne et al. 2021, Périer 2021), in two specific regions: Hamburg (Germany) and Franche-Comté (France), and in particular in pre-school/kindergarten and primary schools. We rely on various semi-structured interviews with families and educational actors in school in the German and French contexts. In this paper we seek to understand and compare the different relationships (home/school) according to the actors in the two research fields and question, among other things, the importance of the national field with its specific history in relation to welcoming policies and the promotion of the home-school relationship. The results will help to whether and how cooperation between school and newly arrived families can facilitate families’ transition to a new school culture.
Activités plurilingues au secondaire Ponts entre l’éducation formelle et non formelle en Grèce et en France
Authors: Gatsi Giota , Dulong Stéphanie
Published: December 2024

Nous présentons le fruit d’ateliers expérientiels et ludiques plurilingues menés auprès d’adolescents en Grèce et en France dans deux contextes différents : l’un formel, dans un collège grec, et l’autre en dehors de l’école, dans une association. Ces ateliers ont été menés dans les établissements des écoles privées (Grèce) dans le cadre des cours de français. Ils ont été réalisés en parallèle par l’association Croisée des langues dans le cadre d’activités périscolaires auprès d’adolescents résidant dans le 13e arrondissement de Paris. Les deux formatrices-chercheuses ont ainsi développé quatre activités plurilingues qui sont à la fois transférables en français et en grec et dans d’autres langues, tout en étant adaptables en contexte formel et non formel. Pour chacune de ces activités, une fiche synthétique utilisable par le formateur est proposée. Ainsi, les objectifs, le matériel nécessaire, la durée, les modalités pédagogiques et le déroulement de l’activité sont exposés afin que le formateur puisse découvrir et réaliser l’atelier avec les adolescents. À cela s’ajoutent des propositions d’adaptations établies suite aux expérimentations réalisées, ainsi que des photos illustrant les ateliers réalisés en Grèce et en France. Cette conception des activités avec des adolescents de différents pays a pour but d’enrichir la recherche sur la didactique du plurilinguisme et d’accompagner les adolescents dans leur construction identitaire en contexte scolaire et postscolaire.
Continuity across languages, cultures, and stakeholders: Carrying plurilingual suitcases into classrooms
Authors: Negrinelli Stefano , Bleichenbacher Lukas , De Zanet Mara , Hug Alsu
Published: December 2024

This study explores the creation and testing of teaching materials aimed at promoting plurilingual and intercultural education in Swiss secondary schools. The piloting of these materials, grouped into six thematic units, involved 207 students from ten classes in Eastern Switzerland, revealing a highly diversified linguistic spectrum including European and non-European languages. The feedback brought to light positive engagement on the part of the students, but also challenges. These included the teaching materials' perceived lack of relevance to the pupil's everyday life outside school, and the difficulty for teachers to fit these activities into their busy schedules. While teachers expressed enthusiasm for plurilingual didactics, they perceived practical limitations due to time constraints as a significant obstacle. However, teachers recognised the potential of these activities to inspire pupils to be creative and alleviate their apprehensions about unfamiliar languages and cultures. The information gathered from the initial testing phases offers valuable insights for refining these materials and aligning them with the practical needs of classroom teaching, presenting an essential guide for effective implementation in different educational contexts, with the aim of ensuring a certain regularity to experiences of plurilingual education.
Teaching how to build bridges between languages
Authors: Sielanko-Byford Elzbieta , Zielińska Janina
Published: December 2024

The article presents examples of activities and tasks used during classes devoted to plurilingual education at the Centre for Foreign Language Teacher Training and European Education of the University of Warsaw.  In the first part of the paper, the context in which future teachers of languages are educated at the Centre is described. The description focuses on the Plurilingual and Pluricultural Education course and the Integrated Language Didactics course, which enable students to become acquainted with the pluralistic approaches to languages and cultures and to further develop their plurilingual and pluricultural competence. These courses are an integral part of the programme of study at the Centre and it is assumed that the students will use the knowledge and skills acquired while attending them in their future work at school in order to facilitate the teaching and learning of languages. The second part of the paper is devoted to activities and tasks presented during the 10th International Conference of the EDiLiC Association. They include an awakening to languages activity, conducted as part of the Plurilingual and Pluricultural Education course at the Centre, and tasks used during the Integrated Language Didactics course for pre-service teachers of English and German or English and French.
Plurilingual Education across Educational Levels – Conceptualization, Curriculum Analysis, and Recommendations for Further Development
Authors: Petra Daryai-Hansen  , Natascha Drachmann
Published: December 2024

In the period 2020-2023, the research and development project Plurilingual Education – Minority and Majority Students' Language Awareness across Educational Levels (PE-LAL) investigated students' language awareness across educational levels in the context of plurilingual education in the mandatory language subjects in primary and lower secondary school (Danish, Danish as a second language, English, French, German) and in Almen Sprogforståelse in upper secondary school. Based on findings from the PE-LAL project, the article focuses on plurilingual education in a Danish educational context. First, the article presents the project's conceptualization of plurilingual education developed through an abductive approach. The conceptualization forms a continuum consisting of three pluralistic approaches and a transversal dimension. Then, based on the conceptualization, the article presents findings from the project's curriculum study showing that plurilingual education is integrated in all language subjects in primary and lower secondary school and in Almen Sprogforståelse in upper secondary school – albert in different ways and with different objectives – leaving the Danish language curriculum with great development potential for plurilingual education. Finally, by drawing on the curriculum findings and other research results from the project, the article concludes with an introduction to the project's Recommendations to strengthen plurilingual education in language subjects in primary and lower secondary school and in Almen Sprogforståelse in upper secondary school in Denmark. The 18 recommendations represent an ideal scenario for how plurilingual education can be strengthened at different levels vertically and horizontally in the Danish educational context, which is why the recommendations address both the macro level (curriculum and teacher education) as well as the meso and micro levels (school, teacher, teaching materials, teaching practice). Each single recommendation is an important contribution to strengthen plurilingual education.
Le matériel didactique dans le projet MEMO : développer les compétences plurilingues dans et pour l’apprentissage du français
Authors: Grimm-Pfefferli Linda , Morkötter Steffi , Schröder-Sura Anna
Published: December 2024

La didactique du plurilinguisme permet un apprentissage approfondi des langues et offre de nombreuses possibilités de soutenir non seulement le développement des répertoires linguistiques et culturels individuels des apprenant·e·s, mais aussi de les utiliser de façon effective et systématique pour l’apprentissage d’une nouvelle langue. Dans notre contribution, il s’agit de présenter des matériaux de didactique du plurilinguisme développés pour le niveau A1 débutant du français en tant que deuxième langue étrangère après l’anglais pour les niveaux primaire, secondaire I et secondaire II. Ce matériel est le fruit d’une collaboration entre des partenaires de quatre pays germanophones dans le cadre d’un projet Erasmus+ intitulé « Modules pour promouvoir le plurilinguisme dans l’enseignement des langues étrangères (MEMO) – Exemples pour un enseignement initial du français sensible aux langues et cultures ». Par-delà les extraits de matériaux didactiques, nous exposerons les idées de base du projet ainsi que la méthodologie pour le développement des modules. Le projet s’inscrit dans la perspective ouverte par les approches plurielles des langues et des cultures et tire profit des descripteurs du CARAP (Cadre de Référence pour les approches plurielles des langues et des cultures) pour définir les compétences visées par les matériaux.
Flersprogethedsdidaktik på tværs af uddannelsesniveauer – konceptualisering, læreplansanalyse og anbefalinger til praksisudvikling
Authors: Daryai-Hansen Petra , Natascha Drachmann
Published: December 2024

Artiklen zoomer ind på flersprogethedsdidaktik i en dansk uddannelseskontekst med afsæt i fund fra forsknings- og udviklingsprojektet Plurilingual Education – Minority and Majority Students’ Language Awareness across Educational Levels (PE-LAL), der i perioden 2020-2023 har undersøgt elevers sproglige opmærksomhed på tværs af uddannelsesniveauer i rammen af en flersprogethedsdidaktik i grundskolens sprogfag (dansk, dansk som andetsprog, engelsk, fransk, tysk) og i overgangen til Almen Sprogforståelse i gymnasiet. Artiklen præsenterer PE-LAL-projektets konceptualisering af flersprogethedsdidaktik, der er udviklet via en abduktiv tilgang. Konceptualiseringen skelner mellem tre flersprogethedsdidaktiske tilgange samt en transversal dimension, der samlet udgør et kontinuum for flersprogethedsdidaktik. Med afsæt i konceptualiseringen fremlægger artiklen efterfølgende fund fra PE-LAL-projektets læreplansstudie, der viser, at flersprogethedsdidaktik er integreret i alle grundskolens sprogfag samt i Almen Sprogforståelse men på forskellige måder og med forskellige formål, hvilket efterlader det danske sprogcurriculum med et stort flersprogethedsdidaktisk udviklingspotentiale. På baggrund heraf samt øvrige forskningsresultater fra PE-LAL-projektet giver artiklen afslutningsvis en introduktion til projektets afsluttende Anbefalinger til en styrket flersprogethedsdidaktik i grundskolens sprogfag og i Almen Sprogforståelse i gymnasiet. De i alt 18 anbefalinger retter sig mod både makroniveau (læreplaner, lærerens grund- og efteruddannelse) samt meso- og mikroniveau (skolen, læreren, undervisningsmaterialer, undervisningspraksis) og er et samlet ønskescenarie for, hvordan flersprogethedsdidaktik kan styrkes på forskellige niveauer vertikalt og horisontalt i den danske uddannelseskontekst. Hver anbefaling udgør et centralt bidrag i sig selv for en styrket flersprogethedsdidaktik.
Клинико-фармакологические подходы к применению антиоксидантной терапии при мужском бесплодии
Authors: О.В. Жукова , Е.В. Ших
Published: December 2024

Мужской фактор служит причиной бесплодия в 24% случаев, причем в 23% наблюдений регистрируются отклонения в анализе спермы. В настоящее время многие исследователи указывают на прогрессирующее снижение качества спермы у мужчин. В последние годы активно обсуждается роль оксидативного стресса в патогенезе мужского бесплодия. Оксидативный стресс, обусловленный высоким содержанием активных форм кислорода (АФК), наблюдается у 30–80% бесплодных пациентов. Сперматозоиды уязвимы для оксидативного стресса, поскольку не  обладают необходимыми цитоплазматическими антиоксидантными системами восстановления, их мембрана богата полиненасыщенными жирными кислотами, что делает их восприимчивыми к перекисному окислению липидов, индуцированному оксидативным стрессом. В семенной плазме содержатся защитные факторы. Поэтому с АФК и свободными радикалами можно бороться, применяя антиоксидантную терапию. Установлено, что  при  совместном применении антиоксиданты проявляют синергические эффекты, что обусловливает эффективность антиоксидантных комплексов в лечении мужского бесплодия. Целесообразно сочетание в комплексе прямых и митохондриальных антиоксидантов. Митохондрии представляют собой источник энергии, являются ключевыми органеллами для подвижности сперматозоидов, акросомальной реакции и оплодотворения. Комплексная антиоксидантная терапия при оксидативном стрессе в первую очередь влияет на подвижность и концентрацию сперматозоидов, что повышает шансы на возможность наступления естественной беременности. В то же время она практически не влияет на морфологию сперматозоидов.

The male factor is the cause of infertility in 24% of cases, with abnormalities in sperm analysis recorded in 23% of cases. Currently, many studies indicate a progressive decline in sperm quality in men. In recent years, the role of oxidative stress in the pathogenesis of male infertility has been actively discussed. Oxidative stress caused by high levels of reactive oxygen species (ROS) is observed in 30–80% of infertile patients. Spermatozoa are vulnerable to oxidative stress because they do not have the necessary cytoplasmic antioxidant recovery systems, their membrane is rich in polyunsaturated fatty acids, which makes them susceptible to lipid peroxidation induced by oxidative stress. Seminal plasma contains protective factors. Therefore, ROS and free radicals can be combated using antioxidant therapy. It has been established that when used together, antioxidants exhibit synergistic effects, which makes antioxidant complexes an effective means of treating male infertility. It is advisable to combine direct and mitochondrial antioxidants in a complex. Mitochondria are a source of energy, are key organelles for sperm motility, acrosomal reaction and fertilization. Complex antioxidant therapy for oxidative stress primarily affects sperm motility and concentration, which increases the chances of natural pregnancy. At the same time, it has virtually no effect on sperm morphology.
Оценка эффективности ферментативных препаратов при лечении хронического простатита
Authors: Е.А. Яковец , Р.Э. Гилязитдинов
Published: December 2024

Хронический простатит, или синдром хронической тазовой боли (СХТБ), представляет актуальную проблему современной урологии. СХТБ сопровождается разнообразными симптомами со стороны нижних мочевых путей, психосоциальными отклонениями и сексуальными нарушениями. Распространенность заболевания варьирует в широком диапазоне – от 2,2 до 41,2%, поэтому необходимо правильно диагностировать его причину для назначения своевременной этиотропной терапии. По данным нескольких исследований, типичные для бактериальных простатитов микроорганизмы образуют биопленки, что приводит к недостаточной диагностике и неэффективности лечения. Доказано, что применение ферментативных препаратов способствует высвобождению микроорганизмов из состава биопленок и увеличивает эффективность антибиотикотерапии. В статье представлены результаты исследования, проведенного с целью оценить эффективность ферментативных препаратов Лонгидаза и Вобэнзим в лечении хронического бактериального простатита. Показано, что использование протеолитических ферментов способствует повышению качества диагностики и эффективности лечения пациентов с хроническим простатитом.

Chronic prostatitis, or chronic pelvic pain syndrome (CPPS), is a pressing problem in modern urology. CPPS is accompanied by various lower urinary tract symptoms, psychosocial abnormalities, and sexual dysfunction. The prevalence of the disease varies widely – from 2.2 to 41.2%, so it is necessary to correctly diagnose its cause to prescribe timely etiotropic therapy. According to several studies, microorganisms typical of bacterial prostatitis form biofilms, which leads to insufficient diagnostics and ineffective treatment. It has been proven that the use of enzymatic preparations promotes the release of microorganisms from biofilms and increases the effectiveness of antibiotic therapy. The article presents the results of a study conducted to evaluate the effectiveness of enzymatic preparations Longidaza and Wobenzym in the treatment of chronic bacterial prostatitis. It has been shown that the use of proteolytic enzymes improves the quality of diagnosis and the effectiveness of treatment of patients with chronic prostatitis.
Determination of the Relationship Between Three-Factor Eating Scale and Chronotypes in Healthcare Workers
Authors: Köleoğlu Mısra Beste , Kenger Emre Batuhan
Published: December 2024

Aim: The aim of this study was to determine the relationship between nutritional status and chronotypes of healthcare workers.
Material and Method: This study was conducted between April and May 2023 on 261 healthcare workers. An online questionnaire form consisting of a general information section, Three-Factor Nutrition Questionnaire and Morning and Evening Questionnaire questions was applied to the participants via Google Forms.
Results: The age and body mass index of the morning people was found to be significantly higher (p
Antibiotic patterns of ampicillin, streptomycin, and tetracycline in stray cats
Authors: Wibisono Freshinta Jellia , Widiasih Dyah Ayu , Fardiansyah Al , Isnaeni Mutia , Mentari Andi Oktaviana , Qurratu'ain Seryna Hasna , Jalal Ismul , Islam Afif Fajrul
Published: December 2024

This research was conducted to determine the presence of Escherichia coli bacteria in anal swabs of wild cats, determine the existence of antibiotic resistance in Escherichia coli bacteria, and determine resistance patterns in Escherichia coli bacteria. A total of 90 swab samples were taken, consisting of 30 anal swab samples from wild cats in the East Surabaya Region and 30 anal swab samples from wild cats in the West Surabaya Region. Samples were tested at the Veterinary Health Laboratory, Faculty of Veterinary Medicine, Wijaya Kusuma University, Surabaya. Samples were brought using buffered peptone water. Samples were isolated and identified using Mac Conkey Agar differential selective media. Isolates identified as Escherichia coli were then subjected to gram staining tests, biochemical tests, and sensitivity tests to determine the presence of resistance and multidrug resistance. The results of the study showed that 95.5% (86/90) of the samples contained Escherichia coli bacteria and the results of the sensitivity test showed that there was antibiotic resistance showing that 25.5% (22/86) were resistant to the antibiotic ampicillin, 19.3% (17/86) were resistant to tetracycline antibiotics, and 13.9% (12/86) were resistant to streptomycin antibiotics. The resistance test results showed that multidrug resistance in Escherichia coli bacteria taken from cat anal swabs was 6.9% (6/86).