bluuebunny/crossref_metadata_2025 huggingface dataset:
Isolation Coronavirus and Rotavirus Associated With Calves, in Central Part of Oromia, Ethiopia
Authors: Seid Umer , Dawo Fufa , Ahmednur Munera , Tesfaye Asamino
Published: November 2020

Background: Coronavirus and Rotavirus are most commonly associated etiologies for calves’ diarrhea resulting in loss of productivity and economy of farmers. However, various facets of diarrheal disease caused by coronavirus and rotavirus in calves in Ethiopia are inadequately understood. A cross sectional study was conducted with the aim of isolation and molecular characterization of coronavirus and rotavirus from calves in central part of Oromia (Bishoftu, Sebata, Holeta and Addis Ababa), Ethiopia from November 2018 to May 2019. The four study areas were purposively selected and fecal samples were collected by simple random sampling for diagnosis of coronavirus and rotavirus infection by using antigen detection Enzyme linked immunosorbent assay (Ag-ELISA) kit. In addition, this study was carried out to have insight in prevalence and associated risk factors of coronavirus and rotavirus infection in calves. Result: During the study 83 diarrheic and 162 non-diarrheic fecal samples collected from calves less than 4 weeks of age were screened for coronavirus and rotavirus. Of the 83 diarrheic samples, 1 sample (1.2%) was positive for coronavirus antigen (Ag) and 6 samples (7.2%) were found to be positive for rotavirus antigen (Ag) by Ag-ELISA. All the non-diarrheic samples were negative for both coronavirus and rotavirus Ag. The overall prevalence of coronavirus and rotavirus infection in calves were estimated as 0.4% (1/245) and 2.45% (6/245) respectively. All samples (7) of ELISA test positive of both coronavirus and rotavirus were propagated in Madin Darby bovine kidney cells (MDBK). After 3 subsequent passages, progressive cytopathic effect (CPE) i.e. rounding, detachment as well as destruction of mono-layer cell of five sample (1 sample of coronavirus and 4 sample of rotavirus) (71.4%) were observed. At the molecular stage, reverse transcriptase polymerase chain reaction (RT-PCR) technique was used to determine the presence of coronavirus and rotavirus nucleic acid by using specific primers. The 5 samples that were coronavirus and rotavirus antigen positive by ELISA and develop CPE on cell culture were also positive on RT-PCR technique. Infection prevalence peaked have been obtained at 1st and 2nd weeks of age in male calves. Conclusion: Diarrheal disease caused by coronavirus and rotavirus has a great health problem in calves that interrupts production benefits with reduced weight gain and increased mortality, and its potential for zoonotic spread. So the present findings show coronavirus and rotavirus infection in calves in Ethiopia that needs to be addressed by practicing early colostrums feeding in newborn calves, using vaccine, or improving livestock management.
Biological Performance of a Bioabsorbable Magnesium–Magnesium Phosphate Cement Interbody Fusion Cage in a Porcine Lumbar Interbody Fusion Model: a Feasibility Study
Authors: Wang Xuxuan , Zhang Yabin , Liu Yihao , Li Xiucan , Mao Keya
Published: November 2020

Background Magnesium phosphate cement (MPC) is a novel biodegradable bone adhesive. The major drawback of the Magnesium phosphate cement (MPC) cage for implantation is its high brittleness. The magnesium was presumed to compensate for the lack of toughness in the MPC cage. The aim of the study was to evaluate the feasibility of a bioabsorbable cage consisting of magnesium and magnesium phosphate cement (MPC) in a porcine lumbar interbody fusion model. Methods Twelve male Ba-Ma mini pigs underwent lumbar discectomy and fusion with an Mg-MPC cage or a PEEK cage at the L3/L4 and L4/L5 level. Computed tomography (CT) scans were made to evaluate the distractive property by comparing average disc space height (DSH) before and at 6, 12, and 24 weeks after the operation. After the lumbar spines were harvested at 6 or 24 weeks after the operation, micro-CT examination was conducted to analyze the fusion rate, and stiffness of motion segments was investigated through mechanical tests. A histological study was performed to evaluate the tissue type in the intervertebral space. Results CT scans showed no significant difference between the two groups in average DSH at each time point. Micro-CT scans revealed an equal fusion rate in both groups (0% at 6 weeks, 83.3% at 24 weeks). Both groups showed time-dependent increases in stability, the Mg-MPC cages achieved an inferior stiffness at 6 weeks and a comparable stiffness at 24 weeks. Histologic evaluation showed the presence of newly formed bone in both groups. However, empty spaces were observed at the interface or around the Mg-MPC cages. Conclusion Compared with the PEEK cages, the Mg-MPC cages achieved comparable distraction, fusion rate, and spinal stability at 24 weeks after the operation. However, due to inferior stiffness at the early stage and fast degradation, further modification of material composition and design are necessary.
Scaling-up community self-reporting rate for COVID-19: Implication for assessing the perceived stigmatization of COVID-19 survivors among residents of Agege local government, Lagos, Nigeria
Authors: Babatunde Olaniyan Akintunde , Amifofun Owoicho Samuel , Sola Sunday Thomas , Akande Abayomi , Besong Mathias , Yesufu Baqiah Morenike , Akanbi Ibukun Mary , Dairo Magbagbeola David
Published: November 2020

Objective: Coronavirus disease 2019 (COVID-19) is an emerging public health problem with over forty-four million confirmed infections globally. Previous studies show that stigma impedes response activities. Therefore, this study was conducted to assess the perceived stigmatization of COVID-19 survivors among residents of Agege local government, Lagos State, Nigeria. We conducted a cross-sectional survey among 333 consenting residents recruited from Agege local government using a multi-stage sampling technique. An interviewer-administered questionnaire was used to collect data on perceived stigmatization. Bivariate and multivariate analyses were done using Chi-square and logistic regression respectively.Results: The mean age of the respondents was 35.7 ± 13.6 years. The proportion of respondents with poor knowledge was 50.5% and awareness for COVID-19 was 95.2%. Television and radio were the two major sources of awareness for COVID-19. A higher likelihood of perceived stigmatization was found among those aged 25 – 49 years (aOR= 3.1, 95% CI = 1.4 – 6.7), ≥ 50 years (aOR= 2.1, 95% CI = 1.1 – 3.9) and married respondents (aOR= 1.8, 95% CI = 1.1 – 2.9). To reduce the effect of stigmatization, we recommend a holistic response plan designed with basic facts about COVID-19 using programmes targeting married respondents as well as the adults.
Early diagnostic value of spectral domain-optical coherence tomography for retrograde optic nerve changes in sellar-occupied patients
Authors: Zhang Li , Yang Xiaowei , Zhang Wei , Han Muyuan , Zhao Wenshuai , Li Xiaohao
Published: November 2020

Background: The comparison of the diagnostic value of peripapillary retinal nerve fiber layer (pRNFL) and macular ganglion cell complex (mGCC) for optic nerve injury has not been reported. The aim of this study was to investigate the value of spectral domain-optical coherence tomography (SD-OCT) in the early diagnosis of optic nerve injury in patients with occupying lesion in sellar region. Methods: A prospective case-control study was conducted for patients who were diagnosed with the occupying lesion in sellar region in the Department of Ophthalmology. The general routine examination and visual field examination were performed. A total of 22 patients (44 eyes) with no abnormalities were selected, and 22 healthy controls (44 eyes) were enrolled (age ≥18 years). SD-OCT was used to detect the average thickness of peripapillary retinal nerve fiber layer (pRNFL) and the thickness of four quadrants and the thickness of each layer of macular ganglion cell complex (mGCC). The results were compared to evaluate the damage of the optic nerve. The area under the receiver operating characteristic (ROC) curve (AUC) was evaluated by SD-OCT to detect the diagnostic efficacy of pRNFL and mGCC for sellar-occupying optic nerve damage. Results: The average thickness of pRNFL was significantly thinner than that of healthy controls (P<0.01). The mean thickness of mGCC, macular retinal nerve fiber layer (mRNFL) and GCL+ were significantly thinner than those of healthy controls (P<0.05). The AUC values ​​of pRNFL, mGCC, ganglion cell layer (GCL) + and mGCC were 0.757, 0.643, 0.702 and 0.688, respectively. The diagnostic value was pRNFL> GCL+ > mGCC > mRNFL. Conclusion: The thickness of pRNFL and mGCC detected by SD-OCT has clinical value in the diagnosis of optic nerve injury in early patients with occupying lesion in sellar region. The change of pRNFL thickness is more effective than mGCC thickness in the early retrograde optic nerve changes, which has potential clinical use value for the diagnosis of retrograde optic nerve changes.
Unique transcriptome and gene expression analysis of rice seedling reveals different cadmium response regulatory mechanisms between indica and japonica rice
Authors: Tong Shan , Luo Xin , Khanzada Hira , Wassan Ghulam Mustafa , Cui Licao , Wu Guangliang , Tan Jingai , Liu Shilei , Li Caijin , Wang Peng , Zhang Xiangyu , Xu Jie , He Haohua , Bian Jianmin
Published: November 2020

Background: In general, the Cd content in indica rice is higher than that in japonica. However, the mechanism underlying this discrepancy has not been elucidated. Thus, understanding the genetic and molecular basis of Cd stress between indica and japonica is highly important for rice improvement programs.Results: In this study, two varieties of rice, japonica 02428 and indica CH891, were continuously exposed to Cd, and seedlings of the two varieties at two critical stages (the 3rd and 5th day) were selected for dynamic gene analysis by the transcriptome method. The results showed that CH891 was more sensitive to Cd than 02428, and a total of 7,204 and 6,670 differentially expressed genes (DEGs) associated with Cd stress were detected on the 3rd day and 5th day, respectively. Furthermore, we divided these DEGs into three categories: SCR (sensitive variety with Cd-responsive), RCR (resistant variety with Cd-responsive) and CCR (common Cd-responsive). The enriched metabolic pathway analysis of DEGs preferentially expressed in a stage-specific and cultivar-specific manner showed that secondary metabolic processes were enriched in SCR, while protein metabolism and plant hormones were enriched in RCR. The diverted metabolic pathways might be the major reason for the different response mechanisms of Cd in indica and japonica rice.Conclusion: These results provide novel insights regarding the Cd response mechanism in rice seedlings between different varieties, and these important Cd-responsive DEGs were frequently involved in specific biological processes and metabolic pathways that might help to elucidate the mechanisms of the indica and japonica rice Cd response differences.
Altered Expression of IL-18, IL-18 Binding Protein and IL-18 Receptor in Blood Monocytes of Patients with Allergic Rhinitis
Authors: Wang Junling , Gu Fangqiu , Li Zhi , Zhan Mengmeng , Wang Ling , Zhang Huiyun , Chen Dong , Xie Hua , Chai Ruonan , Zhao Nan , Yang Ruiming , Hu Yalin , He Shaoheng
Published: November 2020

Background: Interleukin (IL)-18 is emerging as an attractive participant in allergic rhinitis (AR). However, correlation of IL-18 with IL-18 binding protein (BP) in plasma, and expression of IL-18, IL-18BP and IL-18 receptor (R) in AR blood monocytes remain obscure. We therefore investigated IL-18, IL-18BP and IL-18R expression in monocytes using flow cytometric analysis, murine AR model, and quantitative real-time PCR in the present study. Results: Plasma IL-18 and IL-1β in AR patients was higher than those in healthy control subjects. Free (f)IL-18 had a high correlation with IL-18BP, IL-1β and TNF-α in AR plasma. Proportion of IL-18+ monocytes was increased, whereas IL-18BP+ monocytes were decreased in blood of patients with AR. It was found that Platanus pollen allergen extract provoked the elevated expression of IL-18 and IL-18R in AR blood monocytes. Dermatophagoides pteronyssinus, Artemisia sieversiana wild and Platanus pollen allergen extracts enhanced IL-18R protein and mRNA expression in isolated primary monocytes from AR patients. Moreover, numbers of macrophages and IL-18R+ macrophages in nasal lavage fluid (NLF) were increased, and levels of IL-18 in both plasma and NLF were elevated in AR mice. Conclusions: These suggest that IL-18 is likely to participate in the development of AR as a causative factor; therefore, it could be a therapeutic target for AR.
Scalable Computing of Betweenness Centrality based on Graph Reduction with a Case Study on Breast Cancer Analytics
Authors: Chou Chung-Hsien , Wang Shaoting , Shih Hsiang-Shun , Sheu Phillip C-Y.
Published: November 2020

BackgroundGraph theory has been widely applied to the studies in biomedicine such as structural measures including betweenness centrality. However, if the network size is too large, the result of betweenness centrality would be difficult to obtain in a reasonable amount of time.ResultIn this paper, we describe an approach, 1+ɛ lossy graph reduction algorithm, to computing betweenness centrality on large graphs. The approach is able to guarantee a bounded approximation result. We use GSE48216, a breast cancer cell line co-expression network, to show that our algorithms can achieve a higher reduction rate with a trade-off of some bounded errors in query results. Furthermore, by comparing the betweenness centrality of the original graph and the reduced graph, it can be shown that a higher reduction rate does not sacrifice the accuracy of betweenness centrality when providing faster execution time.ConclusionsOur proposed 1+ɛ lossy graph reduction algorithm is validated by the experiment results which show that the approach achieves a faster execution within a bounded error rate.
Nobody’s Land by Desanaka Maksimovic in the Light of the Intertextuality Theory
Authors:   State University of Novi Pazar, Snezana Paser Ilic
Published: November 2020

the collection Nobody’s Land by Desanka Maksimovich. The objective of the study is to consider the features of the poetic world of this collection’s author in the context of oral poetry and prose, as well as in the framework of Serbian ethnomythology. Particular attention is paid to the analysis of the chronotope and transitional rites, illustrated by individual poems. The poems of the collection appear to readers as a multilayered structure, which due to a layer of oral tradition, leads researchers to the depths of Slavic mythology. It is concluded that the author carefully selects those elements from the folklore corps, which are then included in poetic works. A poetess does not create her poems on their interpretation but integrates them into a new context, developing them, changing and expanding the systems of meanings already established in the traditions. As a result, folklore elements (motifs, symbols, heroes, compositional techniques) gain new connotations but their conceptual core remains. Accordingly, these poems can be considered as a new interpretation of the folklore fund. Desanka Maksimovich becomes a poet reinterpreting and saving the domestic literary and mythological heritage from oblivion. Her attention is focused on those components of folklore and mythological creativity, the meaning of which is firmly preserved in the national as well as in the international corps. Desanka Maksimovich’s poems were created in such a way as to allow the researcher to get to the bottom of their folklore and mythological basis, and this indicates a well-thought-out author’s concept. Keywords: poetry, folklore and mythological heritage, chronotope, transitional rites, transposition
Übersetzung von Strafbefehlen — «Wo chiemte mer hi?»
Authors: Thommen Marc , Eschle David , Kuratle Selma , Walser Simone , Zimmermann Fabienne
Published: November 2020

«Wo chiemte mer hi, wenn alli seite, wo chiemte mer hi und niemer giengti für einisch z’luege, wohi dass mer chiem, we me gieng.» Der Berner Pfarrer und Dichter Kurt Marti fragte in seinem wohl berühmtesten Gedicht in der Berner Umgangssprache sinngemäss, wohin wir kämen, wenn niemand den Mut aufbringen würde, den ersten Schritt ins Ungewisse zu wagen. In BGE 145 IV 197 hat das Bundesgericht nicht den Mut gefunden, die Übersetzung von Strafbefehlen konsequent anzuordnen.
Stadistic Study of Accidents and Non-Intentioned Injuries Associated with Kinky-BDSM Practices in The Spanish Comunnity
Authors:   I. Puig Rodas - Societat Catalana de Sexologia, Barcelona, and Universitat de Barcelona - Fee, Barcelona, Spain, Puig Rodas I.
Published: November 2020

Objective: To collect quantitative data about the non-intentioned injuries and accidents associated with kinky-BDSM sexual practices, to provide an objective knowledge in this area. Design and Method: It was performed a questionnaire that included three parts (personal data, sexual behaviour data, and injuries data), and was distributed to kinky-BDSM practitioners, 18 or older, who were living in Spain during the study. The distribution was done in three ways: in person; through Internet social network; and with an Adobe forms questionnaire in the project’ website. All the answers were printed, encoded and filed. The data was processed by statistic functions of Microsoft Excel. Results: We obtained a sample with 119 valid answers (77 men, 40 women, 1 transsexual and 1 with non-specified sex). 71.43% of the sample recognized that had suffered at least one accident performing his/hers practices. The % of persons who admit to have suffered an accident was bigger in the group who use drugs when having BDSM-sex, in comparison to who don’t (83.63% against 65.08%). The most common non-intentioned injuries were hematomas (21.51% of the common injuries); most common cause, a spanking not well performed (21.90% of the common accidents). Most common circumstances where the accidents take place were being accompanied (82.89%) and without drug consumption (81.58%). Only in the 40% of the cases, an external aid was searched. Conclusions: The kinky-BDSM practitioners evidence a risk perception bias, because the practice conceived as most dangerous (autoerotic asphyxia) only causes a few accidents/injuries (1.45%) and doesn’t match with the real most dangerous practice (due to the importance of the injuries), the bondage or the most common (spanking). It has been observed a paradoxical relationship about drug consumption and probabilities of accident. It has been done a feedback of the information obtained to the kinky-BDSM community in Spain so they can start to organize activities to make more secure their activities.
Diagnosis and Non-Pharmacological Treatment for Female Orgasmic Disorder
Authors:   Willingness Malta, Haz-zebbug, Malta, Bartolo M.
Published: November 2020

Objective: This review highlights the most successful non-pharmacological therapies of female orgasmic disorders. Effectivity of different non-pharmacological therapies (sex therapy & communication therapy, bibliotherapy, contact vs. no - contact with therapist, group vs. individual therapy) in the treatment of female orgasmic disorder will be discussed. Design and Method: The inclusion criteria applied in the review included that the studies had to be systemic reviews or randomized controlled trials published from 2005 onwards, had to directly tackle orgasmic problems in females and be written in English language. The exclusion criteria applied were studies that were published before 2005; were not reviews or RCTs; did not tackle orgasmic problems in females, had an organic basis for the sexual problem and were not written in English language. The nine studies that were included were critically appraised using the CASP tools, the SIGN guidelines and the PEDro Scale. After thematic analysis was conducted, four major themes emerged, namely “Sex therapy and communication therapy”; “Bibliotherapy”; “Contact vs. No contact with therapist” and “Group vs. individual therapy”. Results: The result suggests that sex therapy and communication is the most prominent in the studies included. The recommendations suggested are the need for further studies with larger samples so as to get a more comprehensive view of using non-pharmacological therapies. Pereira et al. (2013) underline the fact that Masters and Johnson (1970); and Heiman and LoPiccolo (1988) practices are still the most commonly used. Conclusions: Sex therapy as well as communication skills are the most effective treatment when dealing with FOD.
Mental & Sexual Health Issues in Psychotherapy with Gay Men
Authors:   Praktijk Ruesink, Practice For Psychiatry, Psychotherapy & Sexology, Amsterdam, Ruesink B. ,   Lgbt&psychiatry, Section of The Dutch Society of Psychiatry, Utrecht,   Dutch Society of Sexology, Wormerveer, Netherlands
Published: November 2020

Objective: The prevalence of mental and sexual health problems is high among gay men. They often co exist and do so amongst a certain subgroup of gay men. What kind of mental and sexual health problems are so prevalent? Do mental and sexual health issues interrelate and if so, in what way? Can we define gay men ‘at risk’ for developing sexual and mental problems? How to address the specific health care needs of gay men in psychotherapy? What are the specific characteristics of psychotherapy for gay men? The aim is to learn about and understand these issues. Design and Method: An oral presentation will be given, based on the outcome of international research, literature and clinical practice. Psychiatric interviewing, assessment of sexual functioning, gay specific history taking and aspects of gay specific development are discussed. Interactive discussion with the audience sharing knowledge and clinical experience will deepen our understanding. Results: Mental and sexual health among gay men remains surprisingly poor. Anxiety, depression, mood disorders, suicidality are more common than among heterosexual men. 4/5 of gay men suffer from at least one sexual dysfunction. Treatment focusses on symptom relief and supports gay development. Conclusions: Gay men development is characterized by developmental tasks, challenges and risks. Some gay men get clinical problems: mental, sexual or both for which appropriate treatment is needed. Contemporary issues in psychotherapy with gay men are best addressed by a developmental approach.
Physical Exercise is Negatively Correlated with Premature Ejaculation Symptom Severity
Authors:   Åbo Akademi University, Turku, Finland, Ventus D. , Gunst A. ,   University of Turku, Turku, Finland, Jern P. ,   Åbo Akademi University, Turku; University of Turku, Turku, Finland
Published: November 2020

Objective: To examine associations between symptoms of premature ejaculation and erectile dysfunction and the lifestyle factors alcohol use and physical exercise. Design and Method: An invitation to an online survey was sent out to a population-based sample of Finnish twins and siblings of twins in 2012. Of the 2559 individuals invited, 1054 responded, giving a response rate of 41%. Individuals who used SSRI-medication for any reason were excluded, leaving a final sample of 843. Premature ejaculation was measured by the validated Multiple Indicators of Premature Ejaculation questionnaire, erectile dysfunction by the International Index of Erectile Function – 5, alcohol use by the Alcohol Use Disorders Identification Test, and physical exercise by the Godin Leisure-Time Exercise Questionnaire. Bivariate correlations were used to test associations between variables. Results: There was a significant negative correlation between physical exercise and premature ejaculation symptoms. Premature ejaculation and erectile dysfunction were significantly positively correlated. Effect sizes were moderately small. No significant correlations were found between the other variables. Conclusions: Our results indicate that physical exercise may possibly prevent or counteract premature ejaculation. Future studies could incorporate physical exercise in treatment trials.
Is “Unconsummated Marriage” Still an Appropriate Term? A Snapshot of Reality
Authors:   Institute of Clinical Sexology, Rome, Italy, Silvaggi M. , Michetti P. M. ,   Sapienza University of Rome, Rome, Italy, Fabrizi A. ,   Torvergata University of Rome, Rome, Italy, Rossi R. ,   Institute of Clinical Sexology, Rome, Italy, Tripodi F. M. ,   Institute of Clinical Sexology, Rome, Italy, Simonelli C. ,   Sapienza University of Rome, Rome, Italy
Published: November 2020

Objective: In the middle eastern (MES) and western (WS) societies, sexuality follows different patterns in terms of meaning and rules. Moreover the evolution of societies all around the world created new contexts and kinds of relationship. This could hamper a correct taxonomy of such sexual dysfunctions where social variables are crucial. The aim of the present work is to collect and review data on Unconsummated Marriage (UCM) all around the world, to understand if in different societies it refers to the same situation. Design and Method: A review of published literature on UCM from different areas of the world was conducted. Results: Substantial difference emerged from MES to WS. In MES, sexuality is allowed only in marriage, while in WS sexuality and relationship are not strongly linked. This could suggest that the term “marriage” is unable to cover the phenomenon in such different countries. Moreover, the mean time before the consultation, causal attribution and prevalence are very different in such societies. Conclusions: We found that the term “Honeymoon impotence” could better describe male, female or both difficulties related to ignorance about sexuality or state/performance anxiety, typical in MES. On the other hand in WS over the individual category of sexual dysfunctions, we suggest a new term as “Unconsummated relationship”, where individual difficulties are involved creating a couple’s dysfunction.
Advantages to a Multi-Disciplinary Approach in Sexology
Authors:   Barwon Consulting Suites, Geelong, Australia, Hamilton R.
Published: November 2020

Objective: Many factors influence how a person perceives and accepts sex, the constraints and what facilitates it. Retrospective findings from case presentations highlight such barriers for individuals and couples that impact upon their sexual journey. Design and Method: Retrospective analysis of individuals and couples during a nine month period in 2015. 15 individuals and couples were referred with an assortment of sexual concerns. Key referrals were from General Practitioners (GP’s), Obstetrician/ Gynaecologist (O&G’s), Urologists, Clinical Psychologists and Psychiatrists. Various therapies were incorporated, whilst many continued with a clinical psychologist during this same period. Therapies included Eclectic (incorporating Cognitive Behavioural Therapy), Exposure and Solution Focused. Results: Often, the initial referring presentation/underlying issue was not what became highlighted during consultation with the Sexologist. Barriers to sexual pleasure, sexual understanding and sexual participation, were embedded in poor understanding of basic anatomy and physiology of self and partner. Religion, moral concerns, contraceptive myths and mismanagement, communication styles and compromises were the key underlying issues blocking sexual participation in some manner. Further complexities frequently included a web of spiritual, cultural and/or emotional barriers. Conclusions: Multi-discipline referrals provide the opportunity to rule out many issues through base-line screening/investigations. Having a “team” as such, also promotes a different level of consultation from a Sexologist framework, as a more direct approach is workable with the client/couples and further support and maintenance can be provided especially from a Clinical Psychologist. This presenter has found many benefits working from this approach.
Changes in Sexual Orientation after Treatment for Prostate Cancer
Authors:   Israel Cancer Association, Givataim, Israel, Kurtz Almog L.
Published: November 2020

Objective: According to the statistics, one in six men develops prostate cancer. There are several therapeutic options for prostate cancer. Anti-hormone therapy is one of treatment leading to an 80–90% remission. A significant percentage of men who received anti-hormonal treatment complain of decreased libido and erectile dysfunction. Similarly, these men may also suffer from hot flashes, weight gain, growth of [male] breast tissue (gynecomastia), lack of energy and initiative, depression and mental disorders. In this paper, I would like to present a therapeutic case of a man who received sexual counseling at the Israel Cancer Association, and who, upon receiving antihormonal treatment, changed his sexual orientation after having contracted prostate cancer. Design and Method: A series of meetings were conducted, encompassing an interview and sexual counseling. The Klein Sexual Orientation Grid (KSOG) was used in order to evaluate the patient’s sexual orientation. Results: According to the GRID several parameters such as sexual attraction and sexual behavior were significantly different in the comparison between the past and the present. Parameters such as social preference and hetero/gay style did not change. The remaining results will be presented. Conclusions: Following an analysis of this case, it may be concluded that a person’s sexual orientation can change during his lifetime. The hypothesis is that a life-changing event such as cancer, including all the side effects of difficult antihormonal treatments, has the potential to evoke a change in the person’s overall experience and in his sexual experience in particular.
The Religious Teaching and Women’s Sexuality Construction
Authors:   Midwifery Department, Rafsanjan University of Medical Sciences, Rafsanjan, Iran, Ghorashi Z. , Merghati Khoe E. ,   Brain and Spinal Injury Repair Research Centre (basir), Tehran University of Medical Sciences, Tehran, Iran
Published: November 2020

Objective: In Iran, sexual understandings are strongly determined by religious teaching among women in particular. The aim of this study was to determine the role of religion on Iranian women’s sexual practice evolution. our purpose was to detect women’s individual conceptualization of Islamic Shiite principles and their practice upon these conceptualizations. Design and Method: In this qualitative study, 52 married women in their reproductive age were interviewed (n=4) and participated in eight focus group discussions. They were selected from public health centers in Rafsanjan. Emerged data from the interviews and focus group discussions were analyzed using content analysis. Results: Findings are categorized in three major themes: “unconditional obedience”, ”inconsistency between obedience and virtue”, “misunderstandings”. Conclusions: Religious teaching has a basic and comprehensive role in sexual behavior construction and sexual health of women. However, occasional inconsistency between believes, learning and sexual expectations, practices and situations would lead to jeopardize the psychological and somatic health of women. Misunderstandings have essential role in making such problems.
Student Sex Work In The UK: Facts & Figures
Authors:   Department of Healthcare, Pxl University College, Hasselt, Belgium, Geuens S. , Sagar T. ,   Consortium for Sexuality Studies, Centre for Criminal Justice and Criminology, Swansea, United Kingdom, Jones D. ,   Consortium for Sexuality Studies, Centre for Criminal Justice and Criminology, Swansea, United Kingdom
Published: November 2020

Objective: The Student Sex Work Project was set up at Swansea University (Wales) to locate students involved in the sex industry, discover their motivations and needs, and provide an evidence base for the development of policy and practice with regard to the phenomenon. Design and Method: Data was gathered through an online survey. A crosssectional design was employed. Participation was not randomized. The recruitment of respondents focused on Wales, later extending to the UK. Respondents were recruited through different channels e.g. the NUSE database, strategic campaign, etc. to a total of 6,773 respondents. Ethical approval was granted by the College of Law Research Ethics board at Swansea University. Results: Student involvement in the sex industry in the UK is a fact, both for female and male students. The prevalence of students considering to take up seks work is even larger. Student’s motivations for going into sex work range from financial to pleasure oriented. Conclusions: The student sex work project offers the empirical foundation needed in the ongoing political and academic debates on the phenomenon of student sex work. Data provided by the student sex work project debunks several cultural myths about who we imagine to be the ‘average’ student sex worker.
White Matter Dysconnectivity in Panic Disorder with Early Sexual Abuse History: A Preliminary Study
Authors:   Bundang Cha Hospital, Seongnam, South Korea, Yu S. , Lee S.
Published: November 2020

Objective: People who have experienced childhood abuse are more likely to experience frequent or generalized anxiety or panic disorder (PD). Although previous studies have used magnetic resonance imaging (MRI) to demonstrate structural abnormalities of brain in subjects with PD, there are no study about the brain white matter (WM) connectivity differences between PD with and without early sexual abuse. The objective of this study is to compare the brain WM connectivity between PD with and without early sexual abuse history. Design and Method: Twelve right-handed patients with PD [12 women; 35.91±10.29 (mean±SD) age] who met the diagnostic criteria in Structured Clinical Interview for DSM-IV were examined by means of MRI at 3 Tesla. We divided the patients with PD into two groups with and without early sexual abuse to compare the WM connectivity. Panic Disorder Severity Scale (PDSS), Beck Depression Inventory (BDI) and Anxiety Sensitivity Index-Revised (ASI-R) were administered in PD patients. Results: Tract-based spatial statistics showed that fractional anisotropy (FA) values in PD with sexual abuse history were significantly higher than PD without abuse in the right internal capsule, superior corona radiata, sagittal stratum, fornix. The scores of PDSS, BDI, ASI-R were significantly correlated in the above-mentioned WM regions. Conclusions: This preliminary study suggests that early sexual abuse could influence the connectivity among emotion related limbic structures in PD.
Extradyadic Involvement in Dating Relationships: Prevalence and Factor Structure of The Extradyadic Behavior Inventory
Authors:   Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, Portugal, Martins A. , Andrade R. ,   Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, Portugal, Narciso I. ,   Faculty of Psychology, University of Lisbon, Lisbon, Portugal, Canavarro M. C. ,   Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, Portugal, Dattilio F. M. ,   Harvard Medical School, Boston, Ma, USA, Pereira M. ,   Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, Portugal
Published: November 2020

Objective: High rates of extradyadic involvement during dating have been reported. An increasing attention has been given to extradyadic online interactions. Recently, a measure including a comprehensive list of face-to-face and online extradyadic behaviors (EDB) was developed, the Extradyadic Behavior Inventory (EDBI; Luo, Carter, & Snyder, 2010). The aims of this study were to assess the prevalence rates of face-to-face and online EDB during exclusive dating relationships, and to examine the factor structure of the EDBI. Design and Method: The sample of this cross-sectional study consisted of 947 participants (275 men and 672 women), with a mean age of 23.40 years (SD = 3.99). Participants were in the current relationship for an average of 34 months. Participants completed a self-reported questionnaire on sociodemographic and relational information and the Portuguese version of the Extradyadic Behavior Inventory. Results: Most participants (66.2% of men and 60.4% of women) reported engagement in face-to-face EDB, and 50.2% of men and 42.1% of women reported engagement in online EDB. Men reported significantly higher engagement in online interactions than women. The exploratory factor analysis identified a two-factor structure for both face-to-face (physical/sexual and emotional) and online (sexual and emotional) EDB. Men reported significantly higher scores than women in all forms of extradyadic involvement. Conclusions: The two-factor models identified for face-to-face and online extradyadic involvement are consistent with the perspective that differentiates two types of infidelity – sexual and emotional. By covering a comprehensive list of clearly defined EDB, the EDBI overcomes important limitations of research on infidelity.
The Anti-Inflammatory and Anti-Microbial Effects of the Novel Herbal Formulation (WSY-1075) on Chronic Bacterial Prostatitis Rat Model
Authors:   Department of Urology, Seoul St. Mary’s Hospital, Seoul, South Korea, Bae W. , Choi J. B. ,   Department of Urology, Seoul St. Mary’s Hospital, Seoul, South Korea, Kim K. S. ,   Department of Urology, Seoul St. Mary’s Hospital, Seoul, South Korea, Kim S. J. ,   Department of Urology, Seoul St. Mary’s Hospital, Seoul, South Korea, Cho H. J. ,   Department of Urology, Seoul St. Mary’s Hospital, Seoul, South Korea, Ha U. S. ,   Department of Urology, Seoul St. Mary’s Hospital, Seoul, South Korea, Hong S. H. ,   Department of Urology, Seoul St. Mary’s Hospital, Seoul, South Korea, Lee J. Y. ,   Department of Urology, Seoul St. Mary’s Hospital, Seoul, South Korea, Kim S. W. ,   Department of Urology, Seoul St. Mary’s Hospital, Seoul, South Korea
Published: November 2020

Objective: The aim of this study was to investigate the anti-inflammatory and anti-microbial effects of a new herbal formula (WSY-1075) in a chronic bacterial prostatitis rat model. Design and Method: Thirty two male Wistar rats were used in the study. Experimental chronic bacterial prostatitis was induced by instillation of bacterial suspension (Escherichia coli 108 per ml) into the prostatic urethra. Animals were followed for 4 weeks. After the induction of prostatitis, the rats were randomly divided into one of four treatment groups: control (n=8), ciprofloxacin (n=8), WSY-1075 (400 mg/kg) (n=8), and WSY-1075 (400 mg/kg) + ciprofloxacin (n=8). After 4 weeks of treatment, the prostatic pro-inflammatory cytokine (tumor necrosis factor-alpha, interleukin [IL]-6, and IL-8) levels, anti-oxidant effects (superoxide dismutase) and histological findings were noted. Results: The use of ciprofloxacin, WSY-1075, and WSY-1075 with ciprofloxacin showed statistically significant decreases in bacterial growth and improvements in the reduction of prostatic inflammation compared with the control group (P<0.05). The WSY-1075 with ciprofloxacin group showed a statistically significant decrease in bacterial growth and improvement in prostatic inflammation compared with the ciprofloxacin group (P <0.05). Conclusions: These results suggest that WSY-1075 may have anti-inflammatory and antimicrobial effects, as well as a synergistic effect with ciprofloxacin. Therefore, we suggest that the combination of WSY-1075 and ciprofloxacin may be effective in treating chronic bacterial prostatitis to obtain a higher rate of treatment success.
Do Loving Relationships Have Any Influence on Sexual Desire and on Demand For Sexual Counselling After an Acute Coronary Event?
Authors:   Complejo Asistencial Universitario de Palencia - Department of Accident and Emergency, Palencia, Spain, Domínguez E. M. , Villaizán P. L. ,   Complejo Asistencial Universitario de Palencia - Department of Accident and Emergency, Palencia, Spain, Cabello F. ,   Instituto Andaluz de Sexología y Psicología - Department of Sexology, Málaga, Spain, Del Río F. J. ,   Instituto Andaluz de Sexología y Psicología - Department Of Investigation, Málaga,   Universidad de Cádiz - Department of Methodology, Cádiz, Spain, Bartolomé E. M. ,   Complejo Asistencial Universitario de Palencia - Department of Accident and Emergency, Palencia, Spain, Larrazábal M. ,   Instituto Kaplan de Psicología y Sexología - Department of Sexology, Madrid, Spain, Calaveras J. ,   Complejo Asistencial Universitario de Palencia - Department of Accident and Emergency, Palencia, Spain, Molina N. ,   Instituto Kaplan de Psicología y Sexología - Department of Sexology, Madrid, Spain, Sánchez M. D. ,   Ayuntamiento de Málaga – Department of Civil Rights, Málaga, Spain
Published: November 2020

Objective: To assess whether to have a steady loving relationship changes sexual desire, level of depression and subjective need for sexual counselling to those patients who have suffered an Acute Coronary Syndrome (ACS) episode within the last year Design and Method: The sample consisted of males under 76, with a diagnosis of ACS episode, from September 1st 2014 to August 31st 2015, within the area of The University Health Care Hospital Complex of Palencia. They were appointed by a telephone call at the local Health Center to hold a personal interview in which they answered an inquiry ad hoc and the validated Beck´s Depression Questionnaire and Sexual Desire and Aversion to Sex (DESEA) Questionnaire. Data were analyzed using the statistical program SPSS Statistics 20.0. Results: 73% of patients in our sample had a partner. When applied non-parametric U-Mann-Whitney and Kruskal-Wallis as statistical contrast, it shows that loving relationships do not have any influence neither on patients’ sexual desire, nor on their demand for greater sexual counselling. It was also found that there is a direct correlation between the parameters of DESEA Questionnaire and de score reached on Beck’s Depression Questionnaire. And finally, that a decreased sexual desire will not influence their request for sexual advice. Conclusions: Sexual desire is a characteristic part of each person and that is confirmed in the participants of our research. Patients continued keeping interest for their sexuality after having suffer an ACS within the last year, regardless of the stability of their sexual relationships.
Age of Onset and Quality of Body Image During a Sex Reassignment Program
Authors:   Cidigem Gender Team, Città della Salute e della Scienza Hospital, Turin, Italy, Crespi C. , Molo M. ,   Cidigem Gender Team, Città della Salute e della Scienza Hospital, Turin, Italy, Motta G. ,   Cidigem Gender Team, Città della Salute e della Scienza Hospital, Turin, Italy, Lanfranco F. ,   Cidigem Gender Team, Città della Salute e della Scienza Hospital, Turin, Italy
Published: November 2020

Objective: The aim of the study was to evaluate the quality of body image during a Sex Reassignment Program in a sample of gender dysphoric adults comparing subjects with early onset versus late onset subjects. Design and Method: The sample was composed of 70 gender dysphoric adults (35 transwomen and 35 transmen) before and one year after hormonal treatment. The clinical sessions and the WHO quality of life questionnaire (WHOQOL-100) were used to collect data; in particular we considered the Body Image subscale and some data about plastic surgery. The questionnaire was administered at the beginning of hormonal therapy and at least one year after hormonal treatment to compare the quality of the body image. Results: The majority of the subjects showed a better quality of body image one year after hormonal treatment: the Body Image subscale showed higher scores both in transmen and in transwomen. The comparison between early onset subjects versus late onset subjects didn’t show any statistical significant differences in the quality of body image. Also, no differences have been found between transmen and transwomen. Conclusions: The hormonal treatment showed a positive impact on body image. The quality of the body image doesn’t seem to be influenced by the age of onset.
10 Year Interval Study for Prevalence and Risk Factors of Female Sexual Dysfunction in Korea: Korean Internet Sexuality Survey (Kiss) 2014
Authors:   Department of Urology, Smg-snu Boramae Medical Center, Seoul, South Korea, Son H. , Park J. ,   Department of Urology, Smg-snu Boramae Medical Center, Seoul, South Korea, Cho S. ,   Department of Urology, Smg-snu Boramae Medical Center, Seoul, South Korea, Cho M. ,   Department of Urology, Smg-snu Boramae Medical Center, Seoul, South Korea
Published: November 2020

Objective: We conveyed 10 year interval survey, named Korean Internet Sexuality Survey (KISS) 2014 to investigate the prevalence and the risk factors of Female Sexual Dysfunction (FSD) in Korea. Design and Method: The Internet-based survey was performed in 20-59 year old women via e-mail and they were asked to answer the questionnaire only if they were sexually active, having sex more than once per month during the last 6 months, following the same method of our previous study in 2004. Results: In total, 516 responses were analyzed. The mean age of the subjects was 38.1±10.3. We defined FSD as FSFI total score under 25.0 and the prevalence of FSD was 46.7%. The prevalence of FSD in each age group increased with age: 23.7% in 20s, 45.4% in 30s, 51.4% in 40s and 72% in 50s. The prevalence of FSD in 20s decreased significantly from 44.3% in 2004 to 23.7% in 2014 (p-value=0.000). All six domains of FSD increased with age. Especially, lubrication and pain domain dysfunctions were highly prevalent in 50s. The risk factors for FSD were analyzed as constipation, Beck Depression Inventory (BDI) and Overactive Bladder Symptom Score (OABSS). Women with older age at first intercourse, increasing number of sexual partners and use of contraceptive pill had lower risk to have FSD. Conclusions: FSD was still highly prevalent in Korea and it increased with age. Compared to the previous study, prevalence of FSD in 20s significantly decreased. Further periodic study is necessary to widen the scope of understanding FSD.
Combined Effect of Blood Cadmium and Lead Levels on Testosterone Level in Korean Men
Authors:   Department of Family Practice and Community Health, Ajou Medical Center, Suwon, South Korea, Lee S. , Cho D. ,   Department of Family Practice and Community Health, Ajou Medical Center, Suwon, South Korea, Kim K. ,   Department of Family Practice and Community Health, Ajou Medical Center, Suwon, South Korea, Joo N. ,   Department of Family Practice and Community Health, Ajou Medical Center, Suwon, South Korea, Kim K. ,   Department of Family Practice and Community Health, Ajou Medical Center, Suwon, South Korea
Published: November 2020

Objective: This study was designed to investigate the combined effects of cadmium (Cd) and lead (Pb) on testosterone level in men. Design and Method: The heavy metal dataset of the Korean National Health and Nutrition Examination Survey (KNHANES) IV and V (2008 - 2012) was analyzed. Results: The serum testosterone level was significantly associated with the logtransformed blood Cd and Pb levels. For the highest quartile of Cd and Pb, the odds ratio (OR) of the risk of low serum testosterone level compared with the lowest quartile was 6.890 (Cd, 95% CI: 4.59-10.70) and 3.117 (Pb, 95% CI: 2.03-4.39) after adjusting for confounders (age, body mass index, smoking status, diabetes and alcohol intake), respectively. The adjusted OR of the risk of low serum testosterone level in the 4th quartile of both Cd and Pb was 13.7 (95% CI: 9.0-19.5) compared with the reference group (1st and 2nd quartile of Cd and Pb). Conclusions: This study is the most comprehensive investigation to date regarding the association between heavy metals and sex hormones in males.