bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of On-Bypass Red Blood Cell Transfusion on Severe Postoperative Morbidity or Mortality in Children
Authors: Willems Ariane , Datoussaid Dounia , Tucci Marisa , Sanchez Torres Cristel , De Villé Andrée , Fils Jean-François , Van der Linden Philippe
Published: June 2016

BACKGROUND:

Children undergoing cardiac surgery are frequently exposed to red blood cell (RBC) transfusions mainly in the case of hemorrhage or low oxygen transport. However, in this population, RBCs are sometimes added to the cardiopulmonary bypass (CPB) priming solution to maintain a predefined hematocrit on bypass. In this study, we investigated the impact of RBCs added to the CPB on severe postoperative morbidity or mortality.

METHODS:

This retrospective cohort study was conducted between 2006 and 2012 in a tertiary care level, children’s hospital. Children receiving red cells only to prime the CPB (CPB transfusion) were compared with those receiving no RBCs during their entire hospital stay. The primary outcome was severe postoperative morbidity or mortality. Studied secondary outcomes were neurologic deficit, infection, length of mechanical ventilation, pediatric intensive care unit and hospital length of stay, and mortality. Both groups were compared with propensity score analysis where patients were matched via a genetic matching algorithm. In all analyses, applying a Bonferroni correction, aPvalue <.05/8 = .00625, was considered statistically significant.

RESULTS:

Among the 854 patients retained for this study, 439 (51.4%) received no RBC transfusion during their entire hospital stay and 415 (49.6%) received a CPB transfusion. Thirty-five (8.0%) patients in the no-transfusion group and 110 (26.5%) patients in the CPB transfusion group developed severe postoperative morbidity or died. This difference was statistically significant using univariate analysis (P< .001). Propensity score analysis showed that 79 (19.55%) patients developed severe postoperative morbidity or died in the no-transfusion group compared with 103 (25.50%) patients in the CPB transfusion group (P= .043). The relative risk and its Bonferroni-corrected confidence interval was 0.77 (0.53–1.10). All secondary outcomes were not significantly different between both groups, except the number of patients who developed infections (P< .001).

CONCLUSIONS:

In the condition of our study, adding RBCs to the CPB priming to maintain a predefined hematocrit does not seem to impact markedly severe postoperative morbidity or mortality in children undergoing cardiac surgery. Only the risk of infection was increased in the CPB transfusion group. Further studies are warranted to better understand the complex interaction among severity of illness, anemia, RBCs transfusion, and outcome in children undergoing cardiac surgery.
Genuine Federalism in the Russian Health Care System: Changing Roles of Government
Authors: Chernichovsky Dov , Potapchik Elena
Published: June 2016

The reforms that have affected the Russian health care system since the breakup of the Soviet Union, principally those in the general administration of the Russian Federation, have suffered from inconsistency and the absence of a strategy. The various reforms have caused a shift from a national health system characterized by highly centralized management and control, typical of the totalitarian uniform state, to a highly decentralized but fragmented multitude of state systems. Each of these systems is relatively centralized at the local level and run by local administrations with limited government infrastructure and experience. The role of government in the emerging system, and in particular the role of the federal government, remains ill defined. As a result, there is a grave risk that the Russian health care system may disintegrate as a national system. This undermines (a) the prevailing universal and fairly equitable access to care, (b) stabilization of the system following a long period of transition, and (c) the long-term reform that is required to bring the Russian health care system up to par with the health care systems in other developed countries. A rapid transition to a genuine federal health system with well-articulated roles for different levels of government, in tandem with implementation of the 1993 Compulsory Health Insurance System, is essential for the stabilization and reform of the Russian health care system.
The Feebleness of the Northern Powerhouse
Authors: Hatherley Owen
Published: June 2016

The Northern Powerhouse is an ambitious-sounding plan to revitalize the north of England and create a unified region to rival London. Architectural critic and author Owen Hatherley, however, contends that the Conservative Party’s development strategy mistakenly treats the north as a single entity, and the fiercely independent cities are unlikely to come together.
Metabolic cost of osmoregulation in a hypertonic environment in the invasive African clawed frogXenopus laevis
Authors: Peña-Villalobos Isaac , Narváez Cristóbal , Sabat Pablo
Published: June 2016

Studies of aquatic invertebrates reveal that salinity affects feeding and growth rates, reproduction, survival, and diversity. Little is known, however, about how salinity impacts the energy budget of vertebrates and amphibians in particular. The few studies focused on this topic in vertebrates suggest that the ingestion of salts and the resulting osmoregulatory activity is energetically expensive. We analyzed the effect of saline acclimation on standard metabolic rates (SMR) and the activities of metabolic enzymes of internal organs and osmoregulatory variables (plasma osmolality and urea plasma level) in females of Xenopus laevis by means of acclimating individuals to an isosmotic (235 mOsm NaCl; ISO group) and hyper-osmotic (340 mOsm NaCl; HYP group) environment for 40 days. After acclimation, we found that total and mass-specific SMR was approximately 80% higher in the HYP group than those found in the ISO group. These changes were accompanied by higher citrate synthase activities in liver and heart in the HYP group than in the ISO group. Furthermore, we found a significant and positive correlation between metabolic rates and plasma urea, and citrate synthase activity in liver and heart. These results support the notion that the cost of osmoregulation is probably common in most animal species and suggest the existence of a functional association between metabolic rates and the adjustments in osmoregulatory physiology, such as blood distribution and urea synthesis.
Expression and preliminary characterization of human MICU2
Authors: Li Dan , Wu Wenping , Pei Hairun , Wei Qiang , Yang Qingzhan , Zheng Jimin , Jia Zongchao
Published: June 2016

MICU2 has been reported to interact with MICU1 and participate in the regulation of mitochondrial Ca2+ uptake, although the molecular determinants underlying the function of MICU2 is unknown. In order to characterize MICU2 we screened a series of N-terminal and C-terminal truncations and obtained constructs which can be expressed in abundance, giving rise to soluble samples to enable subsequent characterizations. Size exclusion chromatography (SEC) and multi-angle laser light scattering (MALLS) revealed that MICU2 exists as a monomer in Ca2+-free conditions but forms a dimer in Ca2+-bound conditions. Unlike MICU1, the C-helix domain of MICU2 exhibits no influence on protein conformation in both Ca2+-free and Ca2+-bound forms. Furthermore, mutation of the first EF-hand abolishes the ability of MICU2 to switch to a dimer in the presence of Ca2+, indicating that the first EF-hand is not only involved in Ca2+ binding but also in conformational change. Our pull-down and co-immunoprecipitation assays suggest that, in addition to disulfide bonds, salt bridges also contribute to MICU1-MICU2 heterodimer formation.
Differences in cardiovascular toxicities associated with cigarette smoking and snuff use revealed using novel zebrafish models
Authors: Folkesson Maggie , Sadowska Natalia , Vikingsson Svante , Karlsson Matts , Carlhäll Carl-Johan , Länne Toste , Wågsäter Dick , Jensen Lasse
Published: June 2016

Tobacco use is strongly associated with cardiovascular disease and the only avoidable risk factor associated with development of aortic aneurysm. While smoking is the most common form of tobacco use, snuff and other oral tobacco products are gaining popularity, but research on potentially toxic effects of oral tobacco use has not kept pace with the increase in its use. Here, we demonstrate that cigarette smoke and snuff extracts are highly toxic to developing zebrafish embryos. Exposure to such extracts led to a palette of toxic effects including early embryonic mortality, developmental delay, cerebral hemorrhages, defects in lymphatics development and ventricular function, and aneurysm development. Both cigarette smoke and snuff were more toxic than pure nicotine, indicating that other compounds in these products are also associated with toxicity. While some toxicities were found following exposure to both types of tobacco product, other toxicities, including developmental delay and aneurysm development, were specifically observed in the snuff extract group, whereas cerebral hemorrhages were only found in the group exposed to cigarette smoke extract. These findings deepen our understanding of the pathogenic effects of cigarette smoking and snuff use on the cardiovascular system and illustrate the benefits of using zebrafish to study mechanisms involved in aneurysm development.
Ελληνική βιβλιογραφία 1800–1863. Προσθήκες και συμπληρώσεις
Authors: Ηλιού Φίλιππος
Published: June 2016

No abstract
Από τον μεταφεμινιστικό Λόγο στον μεταφεμινιστικό σεξισμό Η περίπτωση των duckface φωτογραφιών
Authors: Λιότζης Ευάγγελος
Published: June 2016

Ο μεταφεμινισμός, ως ένα διακριτό πολιτισμικό φαινόμενο, αποτέλεσε και συνεχίζει να αποτελεί πεδίο αντιπαράθεσης τόσο εντός της επιστημονικής και φεμινιστικής σκέψης, όσο και στη δημόσια συζήτηση γενικότερα. Οι συγκεκριμένης δομής φωτογραφίες τύπου «σουφρωμένα χειλάκια» (duckface) αποτελούν χαρακτηριστικό δείγμα αναπαραγωγής μιας εκδοχής του μεταφεμινιστικού Λόγου στο σύγχρονο επικοινωνιακό περιβάλλον. Μέσω της εν λόγω περίπτωσης, επιδιώκεται να προσδιοριστεί η συμβολή της μεταφεμινιστικής αισθητικής στην αναπαραγωγή ενός «μεταφεμινιστικά προσανατολισμένου σεξισμού».
Back to the drawing board: Re-thinking the role of GLI1 in pancreatic carcinogenesis
Authors: Hogenson Tara L. , Lauth Matthias , Pasca diMagliano Marina , Fernandez-Zapico Martin E.
Published: June 2016

Aberrant activation of the transcription factor GLI1, a central effector of the Hedgehog (HH) pathway, is associated with several malignancies, including pancreatic ductal adenocarcinoma (PDAC), one of most deadly human cancers. GLI1 has been described as an oncogene in PDAC, making it a promising target for drug therapy. Surprisingly, clinical trials targeting HH/GLI1 axis in advanced PDAC were unsuccessful, leaving investigators questioning the mechanism behind these failures. Recent evidence suggests the loss of GLI1 in the later stages of PDAC may actually accelerate disease. This indicates GLI1 may play a dual role in PDAC, acting as an oncogene in the early stages of disease and a tumor-suppressor in the late stages.
SNPsplit: Allele-specific splitting of alignments between genomes with known SNP genotypes
Authors: Krueger Felix , Andrews Simon R.
Published: June 2016

Sequencing reads overlapping polymorphic sites in diploid mammalian genomes may be assigned to one allele or the other. This holds the potential to detect gene expression, chromatin modifications, DNA methylation or nuclear interactions in an allele-specific fashion. SNPsplit is an allele-specific alignment sorter designed to read files in SAM/BAM format and determine the allelic origin of reads or read-pairs that cover known single nucleotide polymorphic (SNP) positions. For this to work libraries must have been aligned to a genome in which all known SNP positions were masked with the ambiguity base ’N’ and aligned using a suitable mapping program such as Bowtie2, TopHat, STAR, HISAT2, HiCUP or Bismark.

SNPsplit also provides an automated solution to generate N-masked reference genomes for hybrid mouse strains based on the variant call information provided by the Mouse Genomes Project. The unique ability of SNPsplit to work with various different kinds of sequencing data including RNA-Seq, ChIP-Seq, Bisulfite-Seq or Hi-C opens new avenues for the integrative exploration of allele-specific data.
On uniform convergence for distribution functions generated by stable laws
Authors: Arakelyan A. H.
Published: June 2016

Two two-parametric families of densities generated by stable laws are considered. The uniform convergence by both parameters for the introduced families is established.
Approximation of periodic integrable functions in terms of modulus of continuity
Authors: Singh Uaday , Soshal -
Published: June 2016

See PDF.
Fixed points of α – ψ multivalued contractive mappings in cone metric spaces
Authors: Laha Amit Kumar , Saha Mantu
Published: June 2016

Some results on fixed points of α – ψ multivalued mappings of different contractive nature over a cone metric space with a normal constant equal to 1 have been established.
Strategic Planning of Innovative Development As the Basis for the Economic Growth of the Russian Federation
Authors: Горохова  , Gorokhova I. , Парфенова  , Parfenova E.
Published: June 2016

The article discusses the current state of the Russian economy and its innovative

development, as in recent years, very relevant was the question of increasing

economic growth by increasing the volume of production and extraction of fuel

and energy resources, and through the implementation of innovative potential

of the country. To encourage this trend in 2011 approved the Strategy of innovative

development of Russia for the period up to 2020. The article analyses the results

and the conclusions that have already created the infrastructure of the national

innovation system, established and developed the implementation of the

innovative development Program (IDP). As a result of writing problems faced

by state-owned companies in the development of IDP.
Monetary valuation of intellectual human capital in innovative activity
Authors: Fedotova Мarina Alekseevna , Loseva Olga Vladislavovna , Kontorovich Olga Igo-revna
Published: June 2016

The article views the structure of an organization’s intellectual human capital, which integrates both employees’ intellectual, professional and personal abilities to perform innovation activity and their results achieved in the process of this activity. The authors prove the role of intellectual human capital in improving an organization’s innovation activity. Basing on the cost, income, expert and psychological approaches, the article develops the intellectual capital monetary valuation model focused on an increase in the objectivity of measuring its value by means of the individual intellectual and performance report. The application of this model is aimed at activating the innovative development of social and economic entities by increasing the quality and efficiency of intellectual human capital
Global Leadership Model for Health Professions Education – A Case Study of the FAIMER program
Authors: Ladhan Zahra , Shah Henal , Wells Ray , Friedman Stacey , Bezuidenhout Juanita , Heerden Ben van , Campos Henry , Morahan Page S.
Published: June 2016

The health workforce of the 21st century has enormous challenges; health professionals need to be both experts in their field and equipped with leadership and managerial skills. These skills are not part of the regular curriculum, so specific programs bridging this gap are required. Since 2001, FAIMER®, with eight centers across the globe, has worked to create health professions education leaders through transformational learning experiences, developing a global community of practice encompassing over 40 countries. We describe the design, implementation, evaluation, and evolution of the leadership and management curriculum component of the global Institute over 15 years. The curriculum is developed and updated through practices that keep faculty and fellows connected, aligned, and learning together. The article highlights the unique features, challenges faced, and sustainability issues. With a robust mixed methods evaluation, there are substantial reasons to believe that the model works, is adaptable and replicable to meet local needs. The program is playing an important role of answering the call for training positive, strengths-based, collaborative leaders who are socially accountable and embrace the challenges for high quality equitable health care around the globe
Well-being, leadership,andpositive organizationalscholarship: A case study of project-based learning in higher education
Authors: Lucas Nance , Goodman Fallon R.
Published: June 2016

The emerging fields of positive psychology and positive organizational scholarship (POS) contribute new perspectives and approaches for leadership education and leadership development in higher education. While there are emerging empirical studies in these new fields, little connection has been made to the intellectual and practical applications for undergraduate leadership education. In this paper, the authors make a case for the intersection of leadership and positive organizational scholarship in the context of an academic course that combines theory-to-practice using a project-based learning approach. Student learning gains in this course are reported through a pre-post assessment of student’s competency and personal levels of well-being.
Changes in University Students after Joining a Service Leadership Program in China
Authors: Shek Daniel T.L. , Lin Li
Published: June 2016

This study examined the effectiveness of a 4.5-day service leadership program for students from Chinese universities using objective outcome evaluation. The participants were assessed before and after the program, with two post-test measurements (immediate assessment and assessment 12 days after the completion of class learning). At pretest and two posttest time points, the participants completed a questionnaire measuring positive youth development, service leadership qualities and beliefs, and life satisfaction. Results showed that students’ performance in both the immediate posttest and follow-up test was better than that in the pretest. Despite the limitations of the one-group pretest-posttest design, results suggest that the curricular-based service leadership program was effective to promote students’ positive youth development, service leadership qualities and beliefs, as well as life satisfaction, and the effectiveness maintained a short period after the class had ended. While the existing findings are promising, these findings should be replicated in the future.
Toward a Greater Understanding: Utilizing Book Discussions to Effectively Engage Students in the Exploration of Women and Leadership Issues
Authors: Scott Heather Inez Ricks
Published: June 2016

This article examines the use of a book discussion as an instructional tool for developing leadership competency skills in female university students. A book discussion centered on Sheryl Sandberg’s book Lean In was held as a means to conceptualize discourse regarding leadership issues in the arena of women and leadership in a multidisciplinary campus wide symposium. In an effort to assess the effectiveness of such a program to learn about leadership issues, student commentary was collected during the discussion via an audio recording device.

A qualitative exploration of the resulting commentary focused on this initiative as an effort to provide insight into the efficacy of book discussions as a best practice for facilitating the engagement of students in the exploration of leadership issues. As leadership educators seek to develop pedagogical tools that catalyze transformative learning, research regarding tools and methods by which faculty equip students to explore leadership becomes increasingly critical.
Leadership Training in an Industry Context: Preparing Student Leaders for a Chaotic News Media
Authors: Herndon Keith , Krueger Vicki
Published: June 2016

This application brief explains the creation and execution of a leadership training program within the context of journalism education. The news media has experienced profound changes in an era of digital disruption. Massive job loss, financial distress, and ownership consolidation have resulted in a chaotic industry. Promising young journalists have few leadership development mechanisms for learning how to interpret the environment they are about to enter. This program provides student leaders a framework for understanding and coping with the news industry’s challenges. It relies on principles of leadership education to explore change management strategies in times of disruption and emphasizes the ethical responsibilities of news media leaders. Leadership is presented as an active concept based on a model of being and doing.
Who Teaches Leadership? A Comparative Analysis of Faculty and Student Affairs Leadership Educators and Implications for Leadership Learning
Authors: Jenkins Daniel M. , Owen Julie E.
Published: June 2016

This study combines multiple national datasets on leadership educator demographics, education, positions, and experiences, in order to answer the question: Who teaches leadership? Comparing leadership educators across both curricular and co-curricular contexts allows a snapshot of the diverse perspectives of leadership educators and informs a set of critical questions and challenges for the field. Questions about the preparation and socialization of leadership educators, the development of pathways for faculty from traditionally underserved backgrounds, and the multiple roles and identities of leadership educators merit further investigation.
Emergent Spaces of Civic Leadership Education and Development: Understanding the Liberal Arts and Humanities from a Perspective of Civic and Public Work
Authors: Kliewer Brandon W. , Moretto Kristin N. , Purcell Jennifer W.
Published: June 2016

The value of the liberal arts and humanities has increasingly been called into question on multiple fronts. Attempts to bridge the practical and liberal arts through forms of civic professionalism have been gaining traction in larger spheres of influence. This article outlines the results of a deliberative civic engagement forum (n = 42) that created a space for community members from business, education, and non-profit sectors at the National Conference on Service and Volunteerism, to consider the role civic leadership education and development has in liberal arts and humanities programs. The forum was intentionally designed to have participants consider the role of the liberal arts and humanities in redefining the purposes and process of democratic engagement through a lens of civic leadership education and development. This forum was able to gather a group of people from sectors that do not normally speak to the intersection of leadership education and the liberal arts.
Exact Solution Methods for a Generalized Assignment Problem with Location/Allocation Considerations
Authors: Ghoniem Ahmed , Flamand Tulay , Haouari Mohamed
Published: June 2016

We investigate modeling approaches and exact solution methods for a generalized assignment problem with location/allocation (GAPLA) considerations. In contrast with classical generalized assignment problems, each knapsack in GAPLA is discretized into consecutive segments having different levels of attractiveness. To maximize a total reward function, the decision maker decides not only about item knapsack assignments, but also the specific location of items within their assigned knapsacks and their total space allocation within prespecified lower and upper bounds. Mathematical programming formulations are developed for single and multiple knapsack variants of this problem along with valid inequalities, preprocessing routines, and model enhancements. Further, a branch-and-price algorithm is devised for a set partitioning reformulation of GAPLA, and is demonstrated to yield substantial computational savings over solving the original formulation using branch-and-bound/cut solvers such as CPLEX over challenging problem instances.
The Effects of Product Line Breadth: Evidence from the Automotive Industry
Authors: Moreno Antonio , Terwiesch Christian
Published: June 2016

Using a detailed data set from the U.S. automotive industry, we enrich the existing literature on product line breadth with new results that highlight previously unexplored operational aspects of its benefits and costs. We find that expanding product line breadth has a significant effect on increasing mismatch costs arising from the increased demand uncertainty associated with product proliferation. These mismatch costs are manifested through additional discounts and inventories. The effect of product line breadth on mismatch costs is comparable in magnitude to the effect on production costs, suggesting that the operational benefits of inventory pooling achievable by rationalizing product lines can be very substantial. Furthermore, we quantify the benefit of using a platform strategy to mitigate the effects of a broad product line on production costs. Finally, we propose an additional, attribute-based measure of product line breadth and find that product line breadth can work as a hedge against changes in demand conditions. For example, automakers that offer a broader range of fuel economy levels increase their market share and reduce their average discounts as gas prices become more volatile.
Systemic Influences on Optimal Equity-Credit Investment
Authors: Capponi Agostino , Frei Christoph
Published: June 2016

We introduce an equity-credit portfolio framework taking into account the structural interaction of market and credit risk, along with their systemic dependencies. We derive an explicit expression for the optimal investment strategy in stocks and credit default swaps (CDSs). We exploit its representation structure and analyze the mechanisms driving the optimal investment decisions. The transmission of market risk premia is the key mechanism through which systemic influences affect the optimal investment strategy. We develop a novel calibration procedure and find that systemic dependencies are statistically significant when the model is fitted to historical time series of equity and CDS data. An empirical analysis with data of companies in the Dow Jones Industrial Average 30 reveals the critical role of systemic risk in portfolio monitoring.

This paper was accepted by Noah Gans, stochastic models and simulation.
Patients' perspectives of care quality in cardiac outpatient departments
Authors: Maharmeh Mahmoud
Published: June 2016

This study explored cardiac patients' perceptions of the factors affecting the quality of cardiac services in outpatient departments in Jordanian hospitals. Semi-structured face-to-face interviews were conducted with 17 patients attending appointments at two cardiac care centres in Amman, Jordan. Thematic analysis of the data resulted in the identification of three themes: physicians spending insufficient time with patients; inadequate explanations by physicians; and organisational issues. Attention to these factors could improve the quality of healthcare. This could include a role for nurses in giving patients information about their condition and treatment, and educating them on lifestyle issues. Health professionals and decision makers should consider patients' views to improve the quality of cardiac care in OPD.
Shrinkage and Static Bending Properties of Juniperus scopulorum from the Rocky Mountains
Authors: Vaughan D. R. , Mackes K. H
Published: June 2016

Juniperus scopulorum is a common tree in the lower elevations of the Rocky Mountains, and is often removed in restoration treatments. This work reports on selected mechanical and physical properties of J. scopulorum. Ten trees were felled and processed, and a static bending machine was used to test 162 specimens. Additionally, 82 ovendried specimens were assessed for shrinkage and density. Results show an air-dry modulus of elasticity (MOE) of 4,611 MPa, air-dry modulus of rupture (MOR) of 68,460 kPa, green MOE of 3,846 MPa, green MOR of 46,760 kPa, specific gravity of 0.4184 (green basis), and shrinkage value of 7.956 percent. These numbers suggest several new uses for the wood including highway signage, guardrails, and bioenergy feedstock.
Revisiting Hyman: direct democracy, shop steward organisation and labour process conflict at Ford's Dagenham plant
Authors: Sheila Cohen
Published: June 2016

This article utilises detailed research into workplace trade unionism in the Dagenham plant of the Ford Motor Company in the UK to explore fundamental issues of workplace trade union democracy, organisation and struggle. Within this framework, the article re-examines Richard Hyman's influential analysis of workplace trade union representation and ‘bureaucratisation’. It draws on a larger study by the author.
Physical education and sports students’ attitudes towards inclusive education (The sample of Kocaeli University)
Authors: Aydın Mensure , İra Nejat , Meriç Bingül Bergün , Bulgan Çiğdem
Published: June 2016

The aim of this study was to observe if Physical Education and Sports students’ attitudes towards Inclusive Education differ or not. The research was done according to the scanning/screening model. “Personal information form” (2004) - (reformed by Orel and his friends) and “Attitude Scale related to Inclusion” (1995)-(reformed by Antonak & Larivee and adapted into Turkish by Kırcaali & Iftar ) were used for  Kocaeli University School of Physical Education and Sports /Physical Education and Sports Department’s 1st grade and the 2nd grade students (121 students) who didn’t take the Inclusive Education class and the 3rd and 4th grade students (193 students) who took the Inclusive Education class. In the statistical analysis of the research, frequency values of the data (which were obtained from  personal information forms) were surveyed and while analysing the data (obtained from the attitude scale related to inclusion) arithmetic average, standard deviation and t test (for the difference between two groups ) were applied.In statistical analysis and in all parameters  numerical difference was seen on the side of the students who took inclusive education class but no statEistically significant difference was found . (P<0,05). As a result, it can be said that Inclusive Education class had a positive change on the attitudes of  Physical Education teacher candidates towards inclusion.
Effect of D Genome on Wheat Anther Culture Response After Cold and Mannitol Pretreatment
Authors: Lazaridou Theano , Pankou Chryssanthi , Xynias Ioannis , Roupakias Demetrios
Published: June 2016

The present study was conducted to determine the effect of the D genome on embryoid induction and green plant regeneration in wheat anther culture and how it is influenced by low temperature and mannitol treatment. For this reason, the anther culture response of two Canadian bread wheat cultivars and their extracted tetraploids (AABB) was studied. As controls two cultivars well responding to anther-culture (i.e. cvs. Kavkaz/Cgn and Acheron) and a no-responding cultivar (cv. Vergina) were used. Approximately 3000 anthers of these cultivars were cultured and three pre-treatments were applied: cold pre-treatment for 7 and 18 days at 4°C, and 0.3M mannitol for seven days at 4°C. W14 and 190-2 were used as induction and regeneration media, respectively, and the basic MS medium as the rooting medium. No green plants were produced from the tetraploids, which supports the view that the D-genome chromosomes are necessary for androgenic response in wheat. Furthermore, the Canadian cultivars performed better after 18-day pre-treatment at 4°C. The extracted tetraploids produced fewer embryoids and performed better after seven days of cold pre-treatment. The controls well responding to anther culture performed better than the Canadian cultivars, although their best response was recorded after seven-day cold pre-treatment. Cultivar Vergina produced no green plants. The presence of mannitol influenced negatively both embryoid and green plant production. It was concluded that the D genome plays a crucial role in anther culture response of wheat and that this response is influenced by both the genotype and the duration of cold pre-treatment.
Micropropagation of Eryngium campestre L. via Shoot Culture Provides Valuable Uniform Plant Material with Enhanced Content of Phenolic Acids and Antimicrobial Activity
Authors: Kikowska Małgorzata , Thiem Barbara , Sliwinska Elwira , Rewers Monika , Kowalczyk Mariusz , Stochmal Anna , Długaszewska Jolanta
Published: June 2016

An efficient micropropagation protocol for production of genetically uniform clones ofEryngium campestreL. was developed. To determine the effect of nutritional and hormonal factors on shoot and root development and bioactive compounds production, three variants of media differing in the content of macro- and micronutrients, as well as plant growth regulators of various types and concentrations were tested. The highest regeneration (100%), with over 13 shoots per explant, was induced on Murashige and Skoog (MS) medium with 1.0 mg l−1benzyladenine (BA) and 0.1 mg l−1indole-3-acetic acid (IAA). The in vitro derived shoots multiplied through axillary bud formation were rooted and transferred to an experimental plot with 78% frequency of survival. Flow cytometry showed no variation in nuclear DNA between the seedlings and micropropagated plants. Preliminary thin layer chromatography (TLC) analysis indicated that phenolic acids, saponins, flavonoids and acetylenes were present in plant biomass. Ultra high performance liquid chromatography (UHPLC) analysis revealed that shoots and roots from in vitro derived plants and root cultures maintained the ability to produce rosmarinic acid (RA), rosmarinic acid hexoside (RA-HEX) and chlorogenic acid (CGA). The highest phenolic acid content was detected in roots of in vitro regenerated plants. The extract from those roots expressed the highest inhibitory effect against bacteriaStaphylococcus aureus, as well as dermatophytesTrichophyton mentagrophytesandT. rubrum.
Palynofacies patterns of the Highveld coal deposits (Karoo Basin, South Africa): Clues to reconstruction of palaeoenvironment and palaeoclimate
Authors: Wheeler Alexander , Götz Annette E.
Published: June 2016

The early Permian represents a crucial period of climate change in Gondwana. This climate signature is captured in the palynological record that represents the floral assemblage of the region. Palynofacies analysis of the No. 2 Coal Seam of the Highveld Coalfield provides a high-resolution picture of this climatic shift, as well as detailing the vegetation patterns and local environments. Core samples taken from two localities were studied with respect to the characteristics of the plant debris and the palynomorph assemblages to differentiate between regional and local signatures. At both of the sampling localities, the No. 2 Coal Seam is split into a Lower Coal Seam and an Upper Coal Seam by a siltstone and a sandstone intraseam parting, respectively. The uneven palaeotopography and distal depositional environment of the Highveld Coalfield distinguish it from the northern Witbank Coalfield as a river-dominated delta plain, with differences in the palaeoenvironment at each locality. Results from the Lower Coal Seam indicate a fern-dominated lowland and conifer-dominated upland. This gives way to a Glossopteris-dominated lowland and a diverse gymnospermous assemblage in the upland of the Upper Coal Seam. This change in floral composition is also observed in the adjacent Witbank Coalfield and is likely caused by climate amelioration related to the movement of Gondwana away from the South Pole.
Multi objective Flower Pollination Algorithm for solving capacitor placement in radial distribution system using data structure load flow analysis
Authors: Tamilselvan V. , Jayabarathi T.
Published: June 2016

The radial distribution system is a rugged system, it is also the most commonly used system, which suffers by loss and low voltage at the end bus. This loss can be reduced by the use of a capacitor in the system, which injects reactive current and also improves the voltage magnitude in the buses. The real power loss in the distribution line is the I2R loss which depends on the current and resistance. The connection of the capacitor in the bus reduces the reactive current and losses. The loss reduction is equal to the increase in generation, necessary for the electric power provided by firms. For consumers, the quality of power supply depends on the voltage magnitude level, which is also considered and hence the objective of the problem becomes the multi objective of loss minimization and the minimization of voltage deviation. In this paper, the optimal location and size of the capacitor is found using a new computational intelligent algorithm called Flower Pollination Algorithm (FPA). To calculate the power flow and losses in the system, novel data structure load flow is introduced. In this, each bus is considered as a node with bus associated data. Links between the nodes are distribution lines and their own resistance and reactance. To validate the developed FPA solutions standard test cases, IEEE 33 and IEEE 69 radial distribution systems are considered.
One phase active filter with energy storage for active power surge compensation in feed line
Authors: Sowa Kacper , Baszyński Marcin , Piróg Stanisław
Published: June 2016

The paper presents a concept of an active filter with energy storage. This solution can be used for the compensation of momentary one phase high power loads with discontinued power consumption (e.g. spot welding machines). Apart from the typical filtering capabilities, the system’s task is also the continuity of the input power from the feeder line and limiting its fluctuation. The proposed by the author’s solution can produce measurable economic benefits by reducing the rated power necessary to energize periodically operating loads and improving the indicators of electrical energy quality. The developed method of active power surges compensation enables a flexible approach to requirements concerning the rated power of the point to which the periodically operating loads with high peak current value are connected. The tests were conducted on a simulation model specially developed in Matlab & Simulink environment, proving high effectiveness of the presented solution.
Generalized space vector control for current source inverters and rectifiers
Authors: Roseline J. Anitha , Kumaran M. Senthil , Rajini V.
Published: June 2016

Current source inverters (CSI) is one of the widely used converter topology in medium voltage drive applications due to its simplicity, motor friendly waveforms and reliable short circuit protection. The current source inverters are usually fed by controlled current source rectifiers (CSR) with a large inductor to provide a constant supply current. A generalized control applicable for both CSI and CSR and their extension namely current source multilevel inverters (CSMLI) are dealt in this paper. As space vector pulse width modulation (SVPWM) features the advantages of flexible control, faster dynamic response, better DC utilization and easy digital implementation it is considered for this work. This paper generalizes SVPWM that could be applied for CSI, CSR and CSMLI. The intense computation involved in framing a generalized space vector control are discussed in detail. The algorithm includes determination of band, region, subregions and vectors. The algorithm is validated by simulation using MATLAB /SIMULINK for CSR 5, 7, 13 level CSMLI and for CSR fed CSI.
The influence of impurities on the operation of selected fuel ignition systems in combustion engines
Authors: Różowicz Sebastian , Tofil Szymon
Published: June 2016

The paper attempts to determine the impact of fuel impurities on the spark discharge energy and the wear of the spark plug electrode. Spark plugs were analyzed in two typical configurations of the ignition system. A number of tests were conducted to determine the wear of the spark plug electrode exposed to different types of impurities. The spark discharge energy for new and worn spark plugs was determined through calculation.
Low-dose intravenous lipid emulsion for the treatment of severe quetiapine and citalopram poisoning
Authors: Purg Darinka , Markota Andrej , Grenc Damjan , Sinkovič Andreja
Published: June 2016

The treatment of quetiapine and/or citalopram poisoning is mainly supportive and involves gastric lavage, activated charcoal, intubation, and mechanical ventilation. Recently, however, there were reports of successful treatment with intravenous lipid emulsion. Here we report a case of a 19-year-old Caucasian girl who ingested approximately 6000 mg of quetiapine, 400 mg of citalopram, and 45 mg of bromazepam in a suicide attempt. The patient developed ventricular tachycardia and epileptic seizures 12 h after admission to the hospital. As the patient’s condition deteriorated, we combined standard therapy (intubation, mechanical ventilation, and vasopressors) with low-dose intravenous lipid emulsion (ILE) (a total of 300 mL of 20 % lipid emulsion) and normalised her heart rhythm and stopped the seizures. She was discharged to the psychiatric ward after 48 h and home after a prolonged (2-month) psychiatric rehabilitation. Intravenous lipid emulsion turned out to be effective even in the lower dose range than previously reported for quetiapine poisoning in patients presenting with seizure and ventricular arrhythmia. To our knowledge, there are no case reports describing the use of ILE in treating citalopram poisoning.
Discriminative grandparental investment – the impact of grandchild’s gender and sociodemographic parameters
Authors: Kirchengast Sylvia , Putz Beatrix
Published: June 2016

Homo sapiens is a typical cooperative breeder and grandparents are among the most important caregivers besides the mothers. Grandparental investment however differs markedly between maternal and paternal grandparents but also between grandmothers and grandfathers. From an evolutionary viewpoint this differential grandparental investment is mainly explained as a result of paternity uncertainty. On the other hand emotional support and child care help from grandparents may also be associated with sociocultural factors. The present study focused on the impact of grandchild’s gender, but also grandparental age and occupation on discriminative grandparental investment, i.e. solicitude, contact frequency and quality of relationship. 272 adults persons between the age 18 and 35 years (x= 23.5yrs; ±3.7) were enrolled in the study. Patterns of grandparental investment during childhood as well as quality of the grandparent- grandchild relationship were collected retrospectively using a 57 item questionnaire. As to be expected maternal grandmothers showed the highest contact frequency and the highest solicitude while -as to be expected - the paternal grandfather exhibited the lowest degree of investment. Grandparental investment was independent of grandparent category mainly influenced by residential distance. Grandchild’s gender and sociodemographic characteristics of the grandparents in contrast had a minor impact on grandparental caregiving and contact frequency. Contrary, grandchild’s gender was related significantly with the quality of relationship and emotional closeness.
Body composition of Slovak midlife women with cardiovascular complications
Authors: Drozdová Darina , Danková Zuzana , Čerňanová Veronika , Siváková Daniela
Published: June 2016

The aim of this study was to analyse differences in body composition of women with and without cardiovascular complications. Bioelectrical parameters were measured with bioimpedance monofrequency analyser (BIA 101) and tissue electric properties were analysed by bioelectric impedance vector analysis (BIVA). The clinical sample (with CVD) consisted of 254 women ranging in age between 39 and 65 years. The sample of women without CVD consisted of 318 women in the same age range and was created from database of our previous studies. Statistical analysis adjusted for age showed significant differences in body composition characteristics of the studied samples. The results of vector analysis showed significantly different tissue electric properties of women in studied groups, what was confirmed by the Hotelling T2- test (p=0.0000). More women with CVD attained risky mean values of obesity indices of BMI and WHR than their “healthy” counterparts. Among women with CVD 80.2% had higher value of the BMI index than optimal one (>24.9 kg/m2) and 74.4% of women had higher value of the WHR index than optimal (>0.80). From the BIA parameters strong correlation coefficient was found between BMI and FM in both groups (r=0.962 for women with CVD; r=0.968 for relatively healthy women). Our data confirmed that cardiovascular disease complications are strongly linked in body composition changes. The cross-sectional nature of our study makes it difficult to draw conclusions regarding causal pathways, though variables of obesity are in line with unhealthy conditions.
The relationship between facial morphology, body measurements and socio-economic factors
Authors: Jandová Marie , Urbanová Petra
Published: June 2016

Background and aim: The effect of socio-economic factors (living conditions) and parental smoking habits on development of facial morphology and body measurements was studied on a longitudinal Czech sample of 25 girls and 25 boys.

Subjects and methods: A set of studied digitalized photographs taken from 0.5 to 18 years in intervals of 6 months originated in the Brno Longitudinal Study. Facial shape changes of sub-adult participants were described using a configuration of 27 landmarks and further studied by using methods of geometric morphometric and multivariate statistics. In order to localize growth-related shape changes within the face, the studied region was divided into upper, middle and lower facial units and analyzed separately.

Results and conclusion: The results show that in the course of ontogenesis there is a strong correlation between facial shape change and body measurements, height included (r=0.10 and r=0.24 in boys and in girls, respectively). The pubertal spurt of the facial shape change rate was revealed at 10.5 years in girls and at 11.5 years in boys. The earlier onset of the pubertal rate increase in facial shape changes in boys was associated with records of poor living conditions. In addition, the mother’s smoking habits were linked to a noticeable facial shape change.
The Effect of Adding Hesperidin, Diosmin, Quercetin and Resveratrol Extracts to Feed for Turkey Hens on Selected Immunological and Biochemical Blood Indices
Authors: Ognik Katarzyna , Cholewińska Ewelina , Czech Anna
Published: June 2016

It was postulated that naturally occurring phenolic compounds obtained from various plant species may have potential use as feed additives for poultry. Therefore the aim of the study was to compare extracts of hesperidin, diosmin, quercetin and resveratrol in terms of their health-promoting (particularly immunostimulatory) effect on turkeys at different ages. The experiment was conducted on 720 Big 6 turkey hens assigned to 6 experimental groups of 120 individuals (6 repetitions with 20 birds each). The turkey hens in group G-C were the control, receiving a basal compound feed with no experimental additives. The turkey hens in the remaining groups, from the first to the 16th week of life, received a basal diet containing hesperidin (group G-H), diosmin (group G-D), quercetin (group G-Q) or resveratrol (group G-R) in the amount of 200 g per tonne of feed. Ht, Hb, RBC, WBC, lysozyme activity, %PC, IgA, IL-6, GLU, TP and minerals were determined in blood samples. The addition of quercetin or resveratrol in the amount of 200 g per tonne of feed was found to have a beneficial effect on haemoglobin synthesis and phosphorus availability, and may also modulate immunity in turkey hens.