bluuebunny/crossref_metadata_2025 huggingface dataset:
H3K27 of Slc40a1 was methylated in senile mice, YP peptide can demethylate it to restore ferriportin to excrete brain iron, thus alleviating dementia
Authors: Zou Zhenyou , Gao Xiaodie , Gao Xiaodie , Yao Yining , Yao Yining , Gan Xinying , Gan Xinying , Liu Juxia , Liu Juxia , Lei Weixing , Lei Weixing , Li Wenyang , Li Wenyang , Chen Tingting , Chen Tingting , Li Xin , Li Xin , Chen Yongfeng , Chen Yongfeng , Wu Fengyao , Wu Fengyao , Chen Liguan , Chen Liguan , Huang Xiansheng , Huang Xiansheng , Zeng Hongji , Zeng Hongji , Yun Keli , Yun Keli , Guo Xuefeng , Guo Xuefeng , Wei Yuhua , Wei Yuhua , Chen Qiang , Chen Qiang , Kang Man , Kang Man , He Shuyuan , He Shuyuan , Lin Anni , Lin Anni , Mo Jinping , Mo Jinping , Li Haiting , Li Haiting , Yue Xiaoqian , Yue Xiaoqian , Wang Zengxian , Wang Zengxian , Bai Shi , Bai Shi , Wu Lijuan , Wu Lijuan , Xia Bin , Xia Bin , Tang Liling , Tang Liling , Wang Guangliang , Wang Guangliang , Zou Ruyi , Zou Ruyi , Wang Chengqiang , Wang Chengqiang , Liu Huihua , Liu Huihua
Published: October 2022

With aging, iron will accumulate in the brain, catalyzing oxidative radicals that damage brain neurons and induceAlzheimer's disease. In this experiment, we observed that in the brains of senile mice, the iron-exporting protein ferriportin was decreased. Further investigation indicated that H3K27 of the slc40a1 gene was methylated and that the methyltransferase Ezh2 was activated. To discharge the excessive iron in the brains of senile mice, we developed the YP peptide, and with it, we demethylated H3K27me of Slc40a1 by phosphorylation, activating the demethylase Kdm6a and inhibiting methyltransferase Ezh2. Consequently, the transcription of Slc40a1 was enhanced,and ferriportin was resumed. Thesenile brain reacquired the function of iron excretion, and as a result, the radicals in the brain weredecreased,and neuron damage was reduced, which finally restored the intelligence of dementia senile mice. Thus, YP could be a potential drug in the prevention of Alzheimer's disease
Virtual Physical Education: Google Meet as an Alternative Learning Tool for Skill-based Concepts
Authors: Lobo Joseph
Published: October 2022

Google Meet is a videoconferencing application integrated with Google Classroom that may be used for synchronous classes. It is one of the most widely used videoconferencing applications globally as supported by previous scholars. To assess this claim in the current setting of this investigation, the study is focused on exploring the factors that affect students’ acceptance of Google Meet as an alternative learning tool in learning skill-based concepts in Physical Education adapting the Technology Acceptance Model (TAM). After obtaining data from 250 Bachelor of Physical Education students, and after using Partial Least Square-Structural Equation Modeling (PLS-SEM), the results revealed that: (1) perceived ease of use positively predicts perceived usefulness, (2) perceived ease of use and perceived usefulness positively influences students’ behavioral intention to use, and (3) behavioral intention to use positively predicts the actual use of Google Meet. The findings posited that PEOU and PU are the external factors that affect students’ behavioral intention and actual use of the platform in learning skill-based concepts in Physical Education. Since the setting of the study is still in a full-online learning modality, the statistics will be used as a deciding factor by the Physical Education Department and college administration if the said platform may continuously be used in all courses in PE. Recommendations and future research directions are also presented.
Features of energy and protein supply in patients with sepsis: a retrospective observational study
Authors: Luft Valeriy M. , Shlyapnikov S. A. , Demko A. Y. , Lapitsky A. V. , Batyrshin I. M. , Pichugina G. A. , Dubikaytis P. A. , Zolotukhin A. I.
Published: October 2022

INTRODUCTION: Sepsis remains an actual problem of modern medicine. Among other treatment options, timely prescribed optimal nutritional-metabolic support is one of the priority methods of intensive treatment for this category of patients. OBJECTIVE: To study the severity of metabolic dysfunction in sepsis and determine the parameters of optimal substrate supply for this category of patients. MATERIALS AND METHODS: The study included 166 patients with sepsis. We studied the severity of systemic metabolic dysfunction and the impact of various options for energy and protein supply on the course of the disease and its outcome. Energy expenditure and the severity of the catabolic reaction of the body were studied by dynamic evaluation of indicators of indirect calorimetry, actual losses of nitrogen and nitrogen balance. RESULTS: Actual energy expenditure in sepsis reaches its maximum values by the 5–6th day of the disease (33.5 ± 1.8 kcal/kg/day or 2366 ± 126 kcal/day). The average energy consumption in sepsis is 2226 ± 96 kcal/day or 30.9 ± 1.4 kcal/kg/day. Energy supply in sepsis less than 25 kcal/kg/day leads to a significant increase in mortality. Protein losses in sepsis reach their maximum values by the 5–6th day of the disease (1.93 ± 0.12 g/kg/day). The average loss of protein in sepsis is 1.68 ± 0.06 g/kg/day. Protein provision of this category of patients with more than 1.5 g/kg/day contributes to a significant decrease in mortality, relative to patients receiving less protein per day. CONCLUSIONS: Energy supply in the range of 25–35 kcal/kg/day, as well as protein supply of more than 1.5 g/kg/day, significantly contribute to better survival of patients with sepsis.
Gut microbiome and brain: scope and perspectives
Authors: Rincón-Orozco Bladimiro
Published: October 2022

Editorial.
A sharia economic collaboration model and its positive impact on developing of poor villages: A study in Indonesia
Authors: Alam Azhar , Tri Ratnasari Ririn , Habibi Boby , Hanif Noor Athief Fauzul
Published: October 2022

The economic development of villages has a substantial impact on community welfare. It can become the backbone of the national economy. However, significant obstacles in village development are lack of human resources (HR), high poverty rates, poor common welfare, justice, and prosperity values. In 2022, in Indonesia there are 9584 underdeveloped villages. Some of the causes of the weak economic condition of a village are economic potential was not optimized, and excessive government interference stifled creativity and independence. This study seeks to explore the extent of the positive impact of the sharia economic implementation model in developing the village’s economy and the model’s potential as an alternative solution to building the economy of poor villages. This paper used descriptive qualitative methods, observations, and interviews with community leaders, community representatives, and the regency office. The results show that the economic development strategies carried out by Gerdu Village had three stages, namely (1) education and cooperation, (2) implementation and management, and (3) evaluation and planning. In addition, the internal driving factor behind the success of the village’s development lies in the activeness of village leaders in implementing sharia economics. As for cooperation with external parties, National Zakat Institution, related local department government, and other institutions around the village have also actively assisted in its development. Positive impacts on the community include increased employment opportunities, income, tourist visits, and tourism and language village programs. This study is expected to be one of the references to explain the Islamic economy’s role in advancing the poor village’s economy.
AcknowledgmentWe would like to express our utmost gratitude to the Department of Sharia Economic Law Study Program, Universitas Muhammadiyah Surakarta and the Department of Islamic Economics, Universitas Airlangga for supporting this study and its publication process.
Smart Nanomaterials and Their Applications
Authors: Alam M.K.
Published: October 2022

Nanomaterials are one of the most amazing creations of human civilization because of their unprecedented potential. These materials are eminent to own excellent electrical, thermal, optical, strong mechanical strength, and catalytic properties. Gadgets or sensors made of nanoparticles are used to determine harmful substances or contaminants of the environment as well as have human biomedical health applications. They have drawn significant attention in the medical sector for possessing remarkable reactivity, extraordinary molar-extinction coefficient, specificity, long-lasting stability, and stronger absorption. In the case of certain biomedical utilization, the fabricating of nanoparticles is problematic because they lack adequate functional characteristics. Smart nanomaterials grab this attention significantly since they can be triggered by external elements like temperature, pH, light, pressure, enzyme, etc. This chapter intends to provide the classifications and applications of smart nanomaterials as tissue engineering, drug delivery, sensor, etc.
Emerging Nanomaterials in Drug Delivery and Therapy
Authors: Nargis M.
Published: October 2022

Medical science has been influenced in a number of ways by the development of new tools for manipulating materials at the nanoscale. Physicochemical advantages like the greater surface area to mass ratio, ultra-small size, and high level of reactivity have set the nanomaterials apart from bulk materials with the same composition. Due to these unique characteristics, nanomaterials are massively used to get over the drawbacks of traditional medicinal and diagnostic drugs and offer outstanding panoramas. In this chapter, we will focus on the developments of nanomaterials in the fields of drug delivery and disease therapy, with their enormous potential and future prospects.
Fat crystal network reinforced plant-derived polysaccharide-based oleogels
Authors:   Jiangnan University, Meng Zong , Anderson Timothy ,   BASF Corporation
Published: October 2022

Most traditional fats for the food industry take hydrogenated oils and high saturated oils as the base material. However, hydrogenated oils and high saturated oils were widely questioned because of the threat to health caused by trans and saturated fatty acids. Oleogelation is a potential strategy to structure liquid oils to replace traditional fats in foods. The aerogel-templated method allowed plant-derived polymers (polysaccharides and proteins) to prepare oleogels. Methyl-cellulose and xanthan gum were dissolved in waters and aerated to prepare aqueous foams. The molecular network of polysaccharides in aqueous foams was rapidly fixed by the ultra-low temperature freezing method, and aerogels were obtained by freeze-drying. The ultra-low temperature freezing method made aerogels have an average pore size of 36.7 Î¼m and improved the porosity. Because of the open network in aerogels, there was a gap between oleogels fabricated by aerogels and traditional fats. Hence, fat crystals were used to further enhance the network structure in oleogels. Vegetable fats (Palm oil, coconut oil, palm kernel oil, and palm kernel stearin) were used to replace 50% of the soybean oil to enhance oleogels made by the aerogel-templated method. Aerogels had stronger oil absorption ability for oils containing PKS and PKO, reaching 39.6 and 38.24 g/g, respectively. Enhancement effects of different vegetable fats on oleogels were analyzed by the oil binding ability, polarized light microscopy, and rheological test. The crystal network formed by coarse crystals could endow oleogels with higher oil binding ability and more robust solid properties but result in more sensitivity to temperature. Through FTIR analysis, the hydrogen bond between polysaccharides constituting the polymer network was detected. The addition of vegetable fats could make oleogels physical properties of traditional fats, thus making oleogels further in the traditional fat replacement.
Optimization of feed preparation for sunflower meal prior to protein separation using triboelectric belt separation
Authors:   ST Equipment & Technology, Barber Natsuki
Published: October 2022

Triboelectric belt separation (TBS) has a long history in the industrial use for the beneficiation of minerals and fly ash. Recent trends in the use of alternative protein present opportunities to develop TBS use in food and feed applications for dry fractionation of protein. Feed preparation processing prior to separation greatly influences the performance of subsequent separation, yet little data has been published investigating various feed processing methods. Therefore, the present study focuses on exploring the relationship between different milling methods and their effects on protein enrichment performance using TBS.Hammer mill, roller mill and attrition mill were used for size reduction of solvent extracted sunflower meal. Milled sunflower meal was further processed in the pilot scale separator by optimizing the physical and processing parameters. Results are presented comparing the effectiveness of TBS for protein enrichment for feed prepared by the different methods.Hammer milled and attrition milled materials produced a similar median particle size at < 100 µm whereas roller milled material resulted in a coarse median particle size at >400 µm. Separation results indicated that the milling method affected both protein separation and mass yield, as the roller milled material showed an improved protein separation at a higher yield when dried after milling.   Particle size and moisture content are two of the main factors affecting performance of TBS for non-food applications. This study provides evidence that pre-processing of sunflower meal by optimized roller milling and controlled drying can enhance protein separation. In the industrial point of view, this finding will result in further energy savings in processing of electrostatic separation making it even more attractive for food and feed applications.
Evaluation of plant-based milk quality and stability: A commercial analysis
Authors:   Kalsec Inc., Elder Drew , Apil Ashley ,   Kalsec Inc., Redwine James ,   Kalsec Inc.
Published: October 2022

The plant-based food market is rapidly growing and evolving which is nowhere more evident than in the alternative dairy space. Despite dairy milk consumption decreasing, plant-based milk alternatives have seen a steady increase in consumption over the past two decades. As plant-based milk development continues to innovate, new products flood the market from a variety of diverse plant sources such as oat, hemp, and pea. With such varied plant-based milks available, there is a gap in our understanding of what defines quality and therefore stability in these products. This study set out to elucidate factors that influence plant-based milks' quality and stability through testing commercial samples using sensory evaluation and analytical techniques. In an effort to identify attributes that define plant-based milk quality, the sensory profile of almond milk was analyzed throughout accelerated and ambient shelf-life studies and the almond milk was screened for markers of quality using gas chromatography-mass spectrometry. Sensory evaluation found that the almond milk lost its characteristic almond aroma and flavor over storage which aligned with a decrease in benzaldehyde in the analytical data. To better understand the potential reactions causing the degradation of plant-based milks, a variety of plant-based milks were screened for their stability against lipid oxidation using OxipresTM. Soymilk and oat milk were less prone to lipid oxidation than almond milk which is likely a result of their unsaturated fat content. Active research is focusing on testing the performance of antioxidants in plant-based milks to determine their ability to control lipid oxidation as well as any potential flavor modulating effects. While every plant-based milk is unique, the results of these studies indicate that factors that influence their quality and stability include the inherent stability of the plant source as well as the formulation of the plant-based milk.
Modifying plant proteins as microgels for fat replacement applications
Authors:   University of Leeds, Kew Ben , Sarkar Anwesha ,   University of Leeds, Liamas Evan ,   University of Leeds, Sharma Jatin ,   Novozymes North America, Inc.
Published: October 2022

With obesity being an increasing health concern, replacements of calorie-dense fat in diet is a necessity. Proteinaceous microgels have recently been found to have ultra-lubricating properties and are hypothesised to act as excellent fat replacers. However, such microgels have not been applied to more sustainable plant protein which is often associated with generating high friction in between oral contact surfaces and consequently generate astringency issues. The aim of this study was to design novel ultra-lubricating microgels using plant proteins and compare lubrication performance of various volume fractions (10-70 vol%) to that of a fat emulsion. An array of characterisation techniques combining oral tribology using 3D biomimetic tongue surface , rheology, dynamic light scattering (DLS), atomic force microscopy (AFM) and quartz crystal microbalance with dissipation (QCM-D) were used to characterise these newly designed microgels and their surface properties. Potato protein microgels at 5 and 10 wt% protein (PoPM5, PoPM10), pea protein microgel at 15 wt% protein (PePM15) and combined alternative protein microgel at 12.5 wt% (Po5:Pe7.5) were prepared at pH 7.0 by thermally crosslinking the proteins at 80°C for 30 minutes to form gels, followed by shearing. AFM and DLS revealed that microgels were sub-micron sized ranging in diameter from 85 to 232 nm with low polydispersity (‰¤ 0.25) . The microgels were relatively soft with storage modulus varying from 0.35 to 6.5 kPa. Irrespective of the type of proteins used, the microgel dispersions presented excellent lubrication performance especially owing to their adsorption properties as well as high effective viscosities. Strikingly, PePM15 microgels had similar friction coefficient values to that of the 20 wt% oil-in-water emulsion when introduced between 3D biomimetic tongue-like surface. Thus, we demonstrate for the first time that these sustainable protein microgels allow better incorporation of alternative protein in low calorie food without any negative mouthfeel consequences.
Creating functional protein ingredients by cross-processing herring co-products with lingonberry press-cake, shrimp shells or green seaweed
Authors:   Chalmers University of Technology, Zhang Jingnan , Ström Anna ,   Chalmers University of Technology, Undeland Ingrid ,   Chalmers University of Technology
Published: October 2022

Cross-processing herring co-products with lingonberry press-cake, shrimp shells and green seaweed (hereafter referred to as €œhelpers€) was recently reported to mitigate lipid oxidation during pH-shift-based protein isolation but had the drawback to reduce protein yield. Here, four strategies to counteract this yield-reduction were studied; optimized solubilization and precipitation pHs, increased water to raw material ratio as well as application of high shear mechanical homogenization (HSMH) and ultrasonication (US). Beyond effects on protein yield, the impacts of the process conditions on the structural, rheological and functional properties of the recovered proteins were also investigated.Increasing solubilization pH from 11.5 to 12 and decreasing precipitation pH from 5.5 to 5.0 or 4.5, as well as increasing the water-to-raw material ratio significantly improved protein yield with all helpers. Rotor-stator (RS)-HSMH and US also improved protein yield by 5-12% with a more marked effect of the type of helper. Cross-processing herring co-products with antioxidant-rich helpers substantially improved water solubility and emulsification capacity of the protein isolates but the effects of RS-HSMH and US were highly dependent on the type of helper. RS-HSMH helped in mitigating the observed negative impact of cross-processing on gel-forming capacity of protein isolates produced in presence of all three helpers; results with lingonberry press-cake were particularly promising. Altogether, tuning processing conditions as well as adding RS-HSMH and US can help in maximizing protein yield during cross-processing of herring co-products with antioxidant-containing helpers. However, the effects of processing conditions on protein functionality are intimately linked to the type of helpers. The combination of herring co-products with lingonberry press-cake was the most promising and will be subject for further studies.
Fractionation of palm and palm kernel oils for designing high quality commodity and specialty fats
Authors:   Desmet Ballestra Group, Gibon Veronique , Kellens Marc ,   Desmet Ballestra Group
Published: October 2022

Fractionation is the most important application of fat crystallization in edible oil processing. This process commonly consists of a controlled crystallization in bulk crystallizers followed by a separation of the liquid from the crystalline fraction, nowadays mostly carried out with membrane press filters. The motive for this process is evident: since nature endows each fat with a particular composition and distribution of the fatty acids on the glycerol, their use in specific applications is limited.  Palm oil is the most fractionated oil worldwide; its potential for multi-step dry fractionation allows to generate various fractions with peculiar physicochemical properties used in many food formulations.  The original booming of the dry fractionation process has helped palm oil to conquer a strong position on the commodity market in one single step. Other demands for special cuts drifted the industry towards a more sophisticated approach: high iodine value super and top olein with interesting cold resistances, high melting point super stearin (competing with fully hydrogenated products), hard palm mid fraction (for cocoa butter equivalents - CBE) or palm red fractions (high carotene and tocopherol/tocotrienol contents). A hybrid form of palm oil grows in Colombia and Ecuador: the high oleic palm oil has a higher oleic content than conventional palm oil. It can easily be fractionated as refined or semi-refined (red oil); the liquid fractions obtained have excellent cold resistance in one single fractionation step.  Palm kernel oil has a very different triglyceride composition and its applications are quite different; it is known as a source of cocoa butter substitute (CBS) after fractionation and full hydrogenation of the stearin. The fractionation can be carried out in one or two steps, making it possible to produce three different CBS. Various technologies including continuous and static crystallization are being used to produce these specialty fats.
UZAKTAN EĞİTİM ORTAMINDA ÇOCUKLAR İÇİN MÜZİK DİNLEME ETKİNLİKLERİNİN TASARLANMASI
Authors: GÖK Murat
Published: October 2022

Bu araştırmada uzaktan eğitim ortamında kullanılabilecek aktif müzik dinleme etkinlikleri tasarlanarak ilk ve ortaokul müzik dersinde ‘dinleme’ öğrenme alanına yönelik örnek bir modelin ortaya konması amaçlanmıştır. Bu amaç doğrultusunda ortaokul 5. Sınıf düzeyi için aktif müzik dinleme becerilerine yönelik toplam 15 haftalık bir müzik dinleme modülü oluşturulurmuştur. Literatür taraması yönteminin kullanıldığı araştırmada öncelikle ‘aktif müzik dinleme’ kavramı olgusal bağlamları ile ortaya konmuştur. İkinci aşamada ise evrensel literatürde en çok tanımlanan aktif müzik dinleme türleri araştırmacı tarafından Hareki-Psikomotor-Kinestetik Dinleme, Müzik Haritalandırma Yöntemi ile Dinleme, Sözel/Kavramsal/Söz Dizimsel Dinleme ve Yazınsal Özellikli Dinleme boyutlarını içeren dört özellikli bir sınıflamayla 15 ayrı dinleme etkinliğini içeren bir model olarak ortaya konmuştur. Araştırma sonucunda müzik eğitiminde yer alan dört öğrenme alanından müzik dinleme öğrenme alanının uzaktan eğitim ortamında nasıl ele alınabileceği, müzik derslerinde etkili dinleme eğitiminin nasıl yapılabileceği ve aktif müzik dinleme becerisinin nasıl geliştirebileceği ile ilgili önerilerde bulunulmuştur.
Efektivitas vertical jump terhadap kemampuan smash bola voli putra
Authors: Aguss Rachmi Marsheilla , Fahrizqi Eko Bagus , Wicaksono Prabowo Aji
Published: October 2022

Penelitian ini bertujuan untuk mengetahui  efektivitas vertical jump terhadap kemampuan smash bola voli putra ekstrakurikuler SMA Negeri 1 Seputih Banyak, Lampung Tengah. Vertikal jump merupakan tes komponen kebugaran yang sudah umum dilakukan guna mengetahui kekuatan otot kaki atau daya ledak (explosive power) seseorang. Semakin tinggi suatu lompatan yang dilakukan, maka akan semakin kuat otot pada kaki atau daya ledak seseorang. Penelitian ini dilakukan di SMA Negeri 1 Seputih Banyak, Lampung Tengah. Populasi penelitian ini adalah siswa laki-laki dalam ekstrakurikuler bola voli dan sampel berjumlah 12 siswa. Teknik pengambilan sampel menggunakan purposive sampling. Penelitian ini menggunakan metode deskriptif kuantitatif. Hasil dari penelitian menunjukkan lompatan tertinggi adalah 68 cm dan lompatan terendah adalah 40 cm dengan rata rata lompatan dari 12 siswa tersebut adalah 58,14 cm. Selanjutnya untuk lompatan diatas 55 cm rata-rata memiliki kemampuan smash yang baik yang dihasilkan dari lompatan yang baik. Hal tersebut menunjukkan bahwa kemampuan vertikal jump memiliki peran dalam kemampuan smash bola voli.  AbstractThis study aims to determine the effectiveness of vertical jump on the extracurricular men's volleyball smash ability of SMA Negeri 1 Seputih Banyak, Central Lampung. The vertical jump is a common test for fitness components to determine the strength of a person's leg muscles or explosive power. The higher a jump is made, the stronger the muscles in the legs or the explosive power of a person. This research was conducted at SMA Negeri 1 Seputih Banyak, Central Lampung. The population of this study were male students in volleyball extracurricular activities and the sample consisted of 12 students. The sampling technique used purposive sampling. This research uses a descriptive quantitative method. The results of the study showed that the highest jump was 68 cm and the lowest jump was 40 cm with the average jump of the 12 students being 58.14 cm. Furthermore, for jumps above 55 cm, on average, they have a good smash ability resulting from a good jump. This shows that the ability to jump vertical has a role in the ability to smash volleyball.
Analisis Kebutuhan Pengembangan E-Modul Personalized System of Instruction pada Pembelajaran Daring Pendidikan Jasmani
Authors: Widodo Agung , Irianto Djoko Pekik , Graha Ali Satia , Yudanto Yudanto , Juniarta Tonang , Bachtiar Bachtiar
Published: October 2022

Pandemi Covid-19 telah mendisrupsi dunia pendidikan yang mengakibatkan terjadinya migrasi pembelajaran luring menjadi daring. Situasi ini menjadikan tantangan tersendiri bagi pembelajaran Pendidikan Jasmani Olahraga dan Kesehatan (PJOK). Penelitian ini bertujuan untuk mengkaji kondisi pembelajaran daring pendidikan jasmani dan kebutuhan guru terhadap modul elektronik berbasis model pembelajaran Personalized System of Instructions (PSI) pada pembelajaran daring pendidikan jasmani. Penelitian ini menggunakan metode survei. Pengumpulan data dilakukan dengan menggunakan kuesioner elektronik via Google Form yang dibagikan kepada guru-guru anggota Musyawarah Guru Mata Pelajaran (MGMP) PJOK Sekolah Menengah Pertama (SMP) Kabupaten Klaten sebagai responden. Sebanyak 61 responden menjawab dan mengisi kuesioner secara lengkap antara tanggal 7-14 Oktober 2021. Hasil survei menunjukkan tiga temuan yaitu: (1) Kondisi pembelajaran daring pendidikan jasmani belum efektif di masa pandemi Covid-19. Guru mengalami kendala dalam melaksanakan pembelajaran pendidikan jasmani secara daring. (2) Dibutuhkan e-modul sebagai bahan pembelajaran untuk siswa secara mandiri di rumah. (3) Dibutuhkan penerapan model pembelajaran Personalized System of Instructions (PSI) dalam pembelajaran daring pendidikan jasmani. Model pembelajaran PSI diyakini tepat dan efektif sebagai model pembelajaran mandiri. The Covid-19 pandemic has disrupted the world of education resulting in the migration of offline learning to online. This situation makes it a challenge for Physical Education learning. This study aims to examine the conditions of physical education online learning and the teacher's needs for electronic modules based on the Personalized System of Instructions (PSI) learning model in physical education online learning. This study uses a survey method. Data was collected using an electronic questionnaire via Google Form which was distributed to teachers who are members of the Teacher Deliberation Forum for Junior High School Physical Education in Klaten Regency as respondents. A total of 61 respondents answered and filled out the questionnaire completely between October 7-14, 2021. The survey results showed three findings, namely: (1) The condition of online learning for physical education has not been effective during the Covid-19 pandemic. Teachers experience problems in implementing online physical education learning. (2) E-modules are needed as learning materials for students independently at home. (3) It is necessary to apply the Personalized System of Instructions (PSI) learning model in physical education online learning. The PSI learning model is believed to be appropriate and effective as an independent learning model.
Speech-Language Pathologists’ Perceptions of Treating Adolescents and Adults with Developmental Disabilities
Authors: Lee Mi Jin , Choi Seong Hee , Choi Chul-Hee , Lee Kyungjae
Published: October 2022

Purpose: The purpose of the current study was to investigate the perspectives of speech-language pathologists (SLPs) in South Korea about treating adolescents and adults with developmental disabilities.Methods: Survey results of 107 SLPs in South Korea were analyzed in the current study. Descriptive and inferential statistics were used in the analysis procedures.Results: Majority of the participants (92/107 participants) had treatment experience of adolescents and adults with developmental disabilities. However, such a treatment was mainly for middle- and high-school students with developmental disabilities. Furthermore the recognition of necessity of therapy, knowledge and confidence level were higher for middle- and high-school students than adults with developmental disabilities (p < 0.05). In addition, most participants acknowledged that the lack of financial support was a reason for adolescents and adults with developmental disabilities not to receive speech language treatment.Conclusion: The results of the current study emphasized that financial support would be needed to provide more appropriate speech language treatment for adults with developmental disabilities. In addition, there should be more re-education programs on developmental disabilities in order to help SLPs to provide more efficient treatment for adolescents and adults with developmental disabilities.
Comparison of Nasalance Scores with and without Hypernasality Control Device in Adults with Hypernasality: A Preliminary Study
Authors: Song Yun-Kyung
Published: October 2022

The purpose of this study was to compare nasalance scores of the experimental vowels, words and paragraphs with and without ‘Hypernasality Control Device (HCD)’ in adults with hypernasality. Three adults with a cerebrovascular attack or a Parkinson’s disease wore in HCD, were asked to read aloud the experimental vowels, words and paragraphs. Using a Nasometer, the nasalance scores were measured. In all experimental vowels, words and paragraphs, the nasalance scores with HCD were measured lower than those without HCD. These results showed that HCD played a role in regulating nasal resonance in adults with hypernasality. However, various modifications and trials of HCD are required for the adequate modulation of nasal resonance. Additional studies are also required for adults with various degrees of hypernasality.
Reliability and Validity of the Korean Matrix Sentence-in-Noise Recognition Test for Older Listeners with Normal Hearing and with Hearing Impairment
Authors: Jung Yukyung , Han Jaeho , Choi Hyo Jung , Lee Jae Hee
Published: October 2022

Purpose: The aim of this study was to examine test-retest reliability and validity of the adaptive Korean matrix sentence-in-noise test for elderly group with normal hearing (ENH) and elderly group with hearing impairment (EHI).Methods: Twenty ENH listeners and 20 EHI listeners based on the World Health Organization (WHO)-proposed hearing-impairment grade participated. For the test-retest reliability of the Korean matrix sentence-in-noise test, each subject was assessed twice in a 2-week interval using three types of noise: speech-shaped noise, International Collegium of Rehabilitative Audiology noise, and International Speech Test Signal. The test-retest agreement was judged by the intraclass correlation coefficient (ICC) and Bland-Altman plots. To differentiate between real change and random measurement error, the standard error of measurement (SEM) and the minimal detectable change (MDC) were also obtained as another reliability index. For the concurrent validity, the results of the Matrix test were compared to the results of the Korean-version Hearing In Noise Test (K-HINT).Results: The test-retest reliability was good to excellent for ENH and EHI groups (ICC, 0.84~0.98). Both groups showed stable reliability, but the ENH group showed smaller SEM and MDC values than the EHI group. No systematic errors were found from the Bland-Altman plots. The correlation between the results of the Matrix test and the K-HINT test was high, revealing good concurrent validity.Conclusion: The Korean matrix sentence-in-noise test appeared to be valid and reliable for the elderly. The Korean matrix sentence-in-noise test can be utilized for clinical measurement of the speech-in-noise ability of elderly individuals.
Оценка порогов проявления вынужденных нелинейных рассеяний непрерывного лазерного излучения в мощных волоконных усилителях
Authors: Слобожанина М.Г. , Бочкова Н.В. , Бочков А.В. , Слобожанин А.Н.
Published: October 2022

The paper describes a new approach for determining the threshold for stimulated nonlinear scattering in active and passive optical fibers. It is proposed to fix the power of the Stokes component at a certain level, which will make it possible to determine the threshold values ​​of laser radiation powers, which characterize the manifestation of stimulated nonlinear scattering at the expected power level, in a convenient way from the applied point of view. Verification of the obtained expressions is given.
Преимущественное распыление при облучении сплавов газовыми кластерными ионами
Authors: Черныш В.С. , Иешкин А.Е. , Киреев Д.С. , Миннебаев Д.К. , Скрылева Е.А. , Сенатулин Б.Р.
Published: October 2022

Topography and composition of the surface of nickel-based alloys under irradiation with Ar2500+ cluster ions with the energy of 20 keV, and atomic Ar+ ions with the energy of 3 keV have been studied. It has been experimentally found that the surface of the alloys is depleted by a component with a lower binding energy. It is shown that the change in the surface concentrations of the alloy components upon irradiation with cluster ions is an order of magnitude greater than upon sputtering with atomic ions. The degree of change in the surface composition is determined by the ratio of the sputtering yields of the alloy components.
Структура и стабильность композитных гелей на основе коллагена и карбоксиметилцеллюлозы
Authors: Нащекина Ю.А. , Консон В.А. , Сироткина М.Ю. , Нащекин А.В.
Published: October 2022

The creation of biocompatible gels, based on type I collagen is studied. To improve the mechanical properties, 10—30% carboxymethylcellulose (CMC) was added to the collagen gel. It is shown that with an increase in the CMC content up to 30%, the stability of composite gels increases. With the help of scanning electron microscopy it is shown, that the ability of collagen to form native fibrils decreases with the addition of CMC. It was also shown by electrophoresis that the presence of CMC increases the rate of degradation of the composite collagen gel.
Using Web-Based Content to Connect Young People With Real-life Mental Health Support: Qualitative Interview Study
Authors: Adeane Emily , Gibson Kerry
Published: October 2022

Background

Young people experience high rates of mental health problems but make insufficient use of the formal services available to them. As young people are heavy users of the internet, there may be an untapped potential to use web-based content to encourage this hard-to-reach population to make better use of face-to-face mental health services. However, owing to the vast range of content available and the complexities in how young people engage with it, it is difficult to know what web-based content is most likely to resonate with this age group and facilitate their engagement with professional support.

Objective

This study aimed to identify the types of web-based content young people identified as more likely to prompt youth engagement with mental health services.

Methods

This study used a qualitative design conducted within a social constructionist epistemology that recognized the importance of youth empowerment in mental health. Digital interviews using WhatsApp instant messenger were conducted with 37 young people aged 16-23 years who participated as “expert informants” on the priorities and practices of youth in web-based spaces. The data were analyzed using reflexive thematic analysis to identify the types of web-based content that participants believed would encourage young people to reach out to a face-to-face mental health service for support.

Results

The analysis generated 3 main themes related to the research question. First, participants noted that a lack of information about available services and how they worked prevented young people from engaging with face-to-face mental health services. They proposed web-based content that provided clear information about relevant mental health services and how to access them. They also suggested the use of both text and video to provide young people with greater insight into how face-to-face counseling might work. Second, participants recommended content dedicated to combating misconceptions about mental health and negative portrayals of mental health services and professionals that are prevalent in their web-based spaces. They suggested content that challenged the stigma surrounding mental health and help seeking and highlighted the value of mental health services. Finally, participants suggested that young people would be more likely to respond to “relatable” digital stories of using mental health services, recounted in the context of a personal connection with someone they trusted.

Conclusions

This study offers recommendations for professionals and service providers on how to better engage young people with real-life mental health support using web-based content. Web-based content can be used to challenge some of the barriers that continue to prevent young people from accessing face-to-face mental health services and underlines the importance of including young people’s voices in the design of web-based mental health content.
Informing mHealth and Web-Based Eating Disorder Interventions: Combining Lived Experience Perspectives With Design Thinking Approaches
Authors: Jarman Hannah K , McLean Siân A , Rodgers Rachel , Fuller-Tyszkiewicz Matthew , Paxton Susan , O'Gorman Beth , Harris Emily , Shatte Adrian , Bishop Katie , Baumann Tahlia , Mahoney Danielle , Daugelat Melissa-Claire , Yager Zali
Published: October 2022

Background

App-based interventions designed to prevent and treat eating disorders have considerable potential to overcome known barriers to treatment seeking. Existing apps have shown efficacy in terms of symptom reduction; however, uptake and retention issues are common. To ensure that apps meet the needs and preferences of those for whom they were designed, it is critical to understand the lived experience of potential users and involve them in the process of design, development, and delivery. However, few app-based interventions are pretested on and co-designed with end users before randomized controlled trials.

Objective

To address the issue, this study used a highly novel design thinking approach to provide the context and a lived experience perspective of the end user, thus allowing for a deeper level of understanding.

Methods

In total, 7 young women (mean age 25.83, SD 5.34, range 21-33 years) who self-identified as having a history of body image issues or eating disorders were recruited. Participants were interviewed about their lived experience of body image and eating disorders and reported their needs and preferences for app-based eating disorder interventions. Traditional (thematic analysis) and novel (empathy mapping; visually depicting and empathizing with the user’s personal experience) analyses were performed, providing a lived experience perspective of eating disorders and identifying the needs and preferences of this population in relation to app-based interventions for eating disorders. Key challenges and opportunities for app-based eating disorder interventions were also identified.

Results

Findings highlighted the importance of understanding and identifying problematic eating disorder symptoms for the user, helpful practices for recovery that identify personal values and goals, the role of social support in facilitating hope, and aspects of usability to promote continued engagement and recovery.

Conclusions

Practical guidance and recommendations are described for those developing app-based eating disorder interventions. These findings have the potential to inform practices to enhance participant uptake and retention in the context of app-based interventions for this population.
Clinicians’ Perceptions of an Artificial Intelligence–Based Blood Utilization Calculator: Qualitative Exploratory Study
Authors: Choudhury Avishek , Asan Onur , Medow Joshua E
Published: October 2022

Background

According to the US Food and Drug Administration Center for Biologics Evaluation and Research, health care systems have been experiencing blood transfusion overuse. To minimize the overuse of blood product transfusions, a proprietary artificial intelligence (AI)–based blood utilization calculator (BUC) was developed and integrated into a US hospital’s electronic health record. Despite the promising performance of the BUC, this technology remains underused in the clinical setting.

Objective

This study aims to explore how clinicians perceived this AI-based decision support system and, consequently, understand the factors hindering BUC use.

Methods

We interviewed 10 clinicians (BUC users) until the data saturation point was reached. The interviews were conducted over a web-based platform and were recorded. The audiovisual recordings were then anonymously transcribed verbatim. We used an inductive-deductive thematic analysis to analyze the transcripts, which involved applying predetermined themes to the data (deductive) and consecutively identifying new themes as they emerged in the data (inductive).

Results

We identified the following two themes: (1) workload and usability and (2) clinical decision-making. Clinicians acknowledged the ease of use and usefulness of the BUC for the general inpatient population. The clinicians also found the BUC to be useful in making decisions related to blood transfusion. However, some clinicians found the technology to be confusing due to inconsistent automation across different blood work processes.

Conclusions

This study highlights that analytical efficacy alone does not ensure technology use or acceptance. The overall system’s design, user perception, and users’ knowledge of the technology are equally important and necessary (limitations, functionality, purpose, and scope). Therefore, the effective integration of AI-based decision support systems, such as the BUC, mandates multidisciplinary engagement, ensuring the adequate initial and recurrent training of AI users while maintaining high analytical efficacy and validity. As a final takeaway, the design of AI systems that are made to perform specific tasks must be self-explanatory, so that the users can easily understand how and when to use the technology. Using any technology on a population for whom it was not initially designed will hinder user perception and the technology’s use.
The Effectiveness of Virtual Reality Exposure Therapy Module for Reducing Acrophobia Symptoms
Authors: Akpewila Fitryanda , Utami Muhana Sofiati , Ramdhani Neila
Published: October 2022

The amount of places that require a person to be in high-altitude circumstances is a barrier for people who are afraid of heights or also known as acrophobia. The therapist can offer a 3D stimulus using Virtual Reality (VR), making it a more efficient alternative to exposure treatments. Virtual Reality Exposure Therapy is the practice of exposing oneself to a fearful stimulus via a VR camera (VRET). The purpose of this study is to determine the effectiveness of the VRET module in reducing acrophobia symptoms. The pretest-posttest control group design was utilized in the study. Participants with acrophobia were separated into two groups: the control (n=14) and the experimental (n=15) who received VRET treatment. They completed the Acrophobia Questionnaire (AQ) before and after the nine VRET sessions. Compared to control condition, participants in the experimental group reported lower scores in AQ-Anxiety and AQ-Avoidance. Furthermore, each exposure session results in a significant decrease in psychological assessments utilizing the State-Trait Anxiety Inventory and Autonomic Perception Questionnaire scales. A significant decrease has also occurred in the Respiratory Rate and Skin Conductance indicators. According to the findings of this study, the VRET module is effective in reducing the psychological and physiological symptoms of acrophobia.
Stres Akademik dan Perceived Social Support sebagai Prediktor Kesehatan Mental Remaja Akhir
Authors: Salsabila Diana Fitria , Hidayat Ila Nurlaila , Ramdani Zulmi
Published: October 2022

Remaja merupakan kelompok usia yang banyak dibebankan tanggung jawab dan tuntutan baru sehingga banyak ahli mengatakan bahwa remaja sangat rentan mengalami permasalahan psikologis. Remaja yang juga berperan sebagai mahasiswa tak jarang merasakan stres akademik akibat tuntutan dan tekanan dalam perkuliahan. Penelitian ini bermaksud untuk mengeksplorasi peran stres akademik dan perceived social support dalam memprediksi kesehatan mental remaja akhir. Penelitian dilakukan dengan metode kuantitatif yang melibatkan 255 subjek dengan teknik accidental sampling. Hasil uji T, uji F dan analisis regresi linier berganda menunjukkan adanya pengaruh dari stres akademik dan perceived social support terhadap kesehatan mental. Hasil penelitian menyimpulkan stres akademik dan perceived social support menjadi prediktor bagi tinggi rendahnya kesehatan mental remaja akhir.