bluuebunny/crossref_metadata_2025 huggingface dataset:
Vision-Related Quality of Life and Subscale Items Following Intravitreal Ranibizumab Injections for Central Retinal Vein Occlusion
Authors: Okamoto Fumiki , Murakami Tomoya , Sugiura Yoshimi , Morikawa Shohei , Hiraoka Takahiro , Oshika Tetsuro
Published: July 2021

The aim of this study was to evaluate the vision-related quality of life (VR-QOL) before and after intravitreal ranibizumab injections (IVR) for central retinal vein occlusion (CRVO) and investigate subscale items of VR-QOL in detail. This multicenter, open-label, prospective study included 23 patients with treatment naïve CRVO and 22 age-matched normal controls. VR-QOL was assessed by the 25-Item Visual Function Questionnaire (VFQ-25) before and up to 12 months post-treatment. The VFQ-25 composite score and 12 subscales were compared between groups. The VFQ-25 composite scores in CRVO showed significant improvement throughout the treatment period compared with those at the baseline. The VFQ-25 composite score before and after treatment in CRVO was significantly lower than that in normal controls. The subscale items, including general health, general vision, near activities, social functioning, mental health, role difficulties, dependency, and peripheral vision, in CRVO were significantly lower than those in the normal controls even after treatment. Vision-related QOL was low in patients with CRVO before treatment and improved with IVR. Even after treatment, the values of several subscale items were lower than those in normal controls. Patients with CRVO require treatment aimed at further improving visual function as well as social and psychological care.
Superspreading in the COVID-19 Epidemic Due to the Autointerference of Viruses
Authors: Shlyakhover Vladimir , Iabluchanskyi Mykola , Dimaschko Juri
Published: July 2021

It has been shown that autointerference of viruses limiting their replication leads to the emergenceof a new stable asymptomatic state of the infected organism. This state gives viruses the ability tosuperspread and make a main contribution to the epidemic. We assume this to be responsible forthe superspreading in the COVID-19 epidemic.
Measuring Vietnamese social work students’ and non-social work students’ attitudes toward poverty and poor population
Authors: Tien Le Minh
Published: July 2021

The paper reports the results collected from social work students (SW) and non-social work students (NSW) of the Ho Chi Minh City Open University (OU), through attitudes toward poverty and poor people, in Vietnam. The Attitude toward Poverty Short Form (ATP-SF) 21-item (ATP-SF) scale, developed by Yun & Weaver (2010), was used for the data collection. The sample of this study comprises 180 students enrolled at three disciplines such as social work (n= 86), law (n= 34), foreign language (n=30) and economics (n=30). The questionnaire was used to collect the data for the study. Cronbach alpha and independent t-test were run to compare means between two groups of students. All students were voluntarily participated in the survey. Results: A total of 180 social work students and nonsocial work students at Ho Chi Minh City Open University in Vietnam were surveyed. Among them, 86 were social work students, the other 94 students were from law (n=34), foreign language (n=30) and economics (n=30). The survey results showed that, when looking for causes of poverty, social work students and nonsocial work students put most emphasis on structural factors of poverty. However, social work students, compared with nonsocial work students, consider personal deficiency and stigma more important.
Knowledge, attitude, and practice towards COVID-19 among antenatal care clients of Adama hospital medical college, Adama, Ethiopia: A cross sectional study
Authors: Tekeba Tsega-Ab Abebaw
Published: July 2021

Objective

An already overwhelmed health system with many sporadic outbreaks is now threatened by the COVID-19 epidemics. Person-to-person transmission is currently ongoing in the country, making it necessary to control the disease. To guarantee successful disease control, the knowledge, attitudes and, practices people hold towards the disease play an integral role. Therefore, the aim of this study was to determine the knowledge, attitude, and practice towards COVID-19 among antenatal care clients of Adama Hospital Medical College, Adama, Ethiopia.
Results

A cross-sectional study was conducted from May 6, 2021, to May 31, 2021. Among the 292 study participants, 222 (75.3%) had good knowledge and 70 (24%) moderate knowledge status. Significant number of respondents 131 (44.9%) had neutral attitude while 159 (54.5%) had positive attitude. The prevalence of poor practice was 61 (20.9%). Majority of the respondents, 136 (46.6%) had moderate practice level.
Investigation of the Occupational Exposure to Blood-borne Pathogens of Staff at a Third-class Specialist Hospital in 2015-2018: a Retrospective Study
Authors: Ji Yuanyi , Huang Junbo , Jiang Guoguo , Liu Qiaolan , Xiao Dalei , Deng Jianjun
Published: July 2021

Background To understand the current situation of occupational exposure to blood-borne pathogens in a women's and children's hospital and analyze the causes to provide a scientific basis for improving occupational exposure prevention and control measures.Methods We analyzed occupational exposure to blood-borne pathogens in a third-class women's and children's hospital from 2015 to 2018, considering the workers’ occupational categories and length of service; the sites, types, and causes of exposure; and the pathogens of the source patients.Results From 2015 to 2018, there were 146 cases of occupational exposure to blood-borne pathogens, mainly from sharp-instrument injuries (82.2%). Trainees represented the highest proportion of occupational exposure (30.1%), followed by nurses (29.5%). Occupational exposure among staff with less than one year of service accounted for 43.2% of cases. Fisher's exact test showed that different occupational groups had different types of occupational exposure, and nurses had the highest proportion of blood and body fluid exposure (P = 0.008). Different occupational groups faced exposure to different types of pathogens: medical staff were more likely than workmen to be exposed to hepatitis B, while workmen were more likely than medical staff to be exposed to unknown pathogens; these differences were statistically significant (P<0.001). Health records were established for all cases of occupational exposure to blood-borne pathogens, and no staff members contracted a blood-borne disease due to occupational exposure.Conclusions In order to reduce occupational exposure, regular training in occupational protection for junior medical staff and workers should be strengthened, the monitoring and protection system of occupational exposure to blood-borne pathogens improved, standard prevention measures strengthened, operations standardized, safe injection equipment provided, and comprehensive measures taken.
Avaliação e expansão da Pós-Graduação em Educação no Brasil e no Nordeste
Authors: Oliveira Larissa
Published: July 2021

O artigo objetiva analisar como as políticas implementas pela Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Capes), tem refletido na expansão e na avaliação dos Programas de Pós-graduação em educação no Brasil, com destaque para a região Nordeste. Parte do pressuposto que as políticas adotadas na pós-graduação, assumem uma lógica de eficiência e produtividade que incentivam a competitividade entre os programas. Trata-se de uma pesquisa qualitativa que usou como procedimentos metodológicos, análises documentais e elaboração de séries estatísticas tomando como referência os dados disponibilizados pelo Sistema de Informações Georefenciadas (Geocapes). O estudo mostra que as políticas concebidas pela Capes propiciaram uma expansão do sistema de pós-graduação, a adoção de novos formatos de programas e que o processo de avaliação tem sido utilizado como forma de garantir a qualidade dos mesmos, ranqueando os programas e aumentando as assimetrias regionais.
Erythrocyte-cancer Hybrid Membrane-camouflaged Mesoporous Silica
Nanoparticles Loaded with Gboxin for Glioma-targeting Therapy
Authors: Jiao Xiuxiu , Yu Xiaoyan , Gong Chunai , Zhu Hao , Zhang Bin , Wang Rong , Yuan Yongfang
Published: July 2021

Objective:

The purpose of this research is to formulate a biomimetic drug delivery system, which can selectively target glioblastoma (GBM) to deliver the antitumor agent, Gboxin, a novel Complex V inhibitor. Gboxin can specifically inhibit GBM cell growth but not normal cells.

Methods:

In the present study, we utilized red blood cell (RBC) membrane and U251 cell membrane to obtain a hybrid biomimetic membrane (RBC-U), and prepared RBC-U coated Gboxin-loaded mesoporous silica nanoparticles ((MSNs/Gboxin)@[RBC-U]) for GBM chemotherapy. The zeta potential, particle size, and morphology of (MSNs/Gboxin)@[RBC-U] were characterized. The cellular uptake, effect of cells growth inhibition, biocompatibility, and specific self-recognition of nanoparticles were evaluated.

Results:

The (MSNs/Gboxin)@[RBC-U] was successfully fabricated and possessed high stability in the circulation system. The drug loading of Gboxin was 13.9%. (MSNs/Gboxin)@ [RBC-U] could effectively retain drugs in the physiological environment and released Gboxin rapidly in the tumor cells. Compared to the MSNs/Gboxin, the (MSNs/Gboxin)@[RBC-U] exhibit highly specific self-recognition to the source cell line. Additionally, the (MSNs/Gboxin) @[RBC-U] showed excellent anti-proliferation efficiency (IC50 = 0.21 μg/mL) in the tumor cell model and few side effects in normal cels in vitro.

Conclusion:

The (MSNs/Gboxin)@[RBC-U] exhibited significant anti-cancer effects in vitro and the specific self-recognition to GBM cells. Hence, (MSNs/Gboxin)@[RBC-U] could be a promising delivery system for GBM targeted therapy.
Involvement of the Renin-Angiotensin System in Stress: State of the Art
and Research Perspectives
Authors: Correa Bernardo H. M. , Becari Luca , Fontes Marco Antônio Peliky , Simões-e-Silva Ana Cristina , Kangussu Lucas M.
Published: July 2021

:

Along with other canonical systems, the renin-angiotensin system (RAS) has shown essential roles in stress. This system is a complex regulatory proteolytic cascade composed of various enzymes, peptides, and receptors. Besides the classical (ACE/Ang II/AT 1 receptor) and the counter-regulatory (ACE2/Ang-(1-7)/Mas receptor) RAS axes, evidence indicates that non-classical components, including Ang III, Ang IV, AT 2, and AT 4, can also be involved in stress. Objective and methods: This comprehensive review summarizes the current knowledge on the participation of RAS components in different adverse environmental stimuli stressors, including air-jet stress, cage switch stress, restraint stress, chronic unpredictable stress, neonatal isolation stress, and post-traumatic stress disorder. Results and conclusion: In general, activating the classical RAS axis potentiates stress-related cardiovascular, endocrine, and behavioral responses, while the stimulation of the counter-regulatory axis attenuates these effects. Pharmacological modulation in both axes is optimistic, offering promising perspectives for stress-related disorders treatment. In this regard, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are potential candidates already available because they block the classical axis, activate the counter-regulatory axis, and are safe and efficient drugs.
The Effect of Counseling on Breastfeeding Self-Efficacy (BSFE) in Women
with Gestational Diabetes
Authors: Vakilian Katayon , Poorghasemian Rezvan , Khorsandi Mahboobeh
Published: July 2021

Background:

Different strategies have been suggested to increase successful breastfeeding, including establishing child-friendly hospitals, prenatal training courses, and various counseling models in breastfeeding self-efficacy enhancement in women with gestational diabetes.

Objectives:

This study aimed to determine the effect of counseling on breastfeeding self-efficacy in women with gestational diabetes.

Methods:

The present study was a quasi-experimental intervention conducted on 100 pregnant women with gestational diabetes after obtaining informed consent. The intervention group received breastfeeding counseling based on the GATHER approach in the third trimester of pregnancy between 32 and 33 weeks and between 35 and 36 weeks of pregnancy, respectively. The follow-up process was performed in 4 sessions after delivery: 14 to 16 days after delivery and 28 to 30 days after delivery for 60 to 90 minutes. The control group, on the other hand, only received routine care. After counseling, self-efficacy was examined at the end of the study and after the third month. The data were analyzed using statistical independent t-tests and chi-square.

Results :

The mean score of self-efficacy of breastfeeding at the end of the study was 55.12 in the experimental group, which was higher than that of the control group (46.16) (P =0.0001). The frequency percentage of exclusive breastfeeding was 58% in the experimental group and 22% in the control group (P =0.0001).

Conclusion:

Considering the effectiveness of breastfeeding counseling on increasing self-efficacy and continuity of breastfeeding in diabetic breastfeeding mothers, it is suggested to use prenatal and continued in postnatal for diabetic mothers.
Contrast-enhanced Ultrasound for Diagnosis of Renal Cystic Mass
Authors: Xia Qingqing , Yuan Xinchun , Huang Meifeng , Zhou Xiling , Zhou Zhiyu
Published: July 2021

Background:

Cystic Renal Cell Carcinoma (CRCC) is often difficult to differentiate
from complex cysts with sonographic manifestations of renal carcinoma. Contrast-Enhanced Ultrasound
(CEUS) is a new technology, and its clinical utility in the diagnosis of renal cystic mass has
not been established.

Objective:

The objective of this study is to analyze the characteristics of CEUS of renal cystic masses
and to explore the clinical significance and value of CEUS in the diagnosis of CRCC.

Methods:

This study was a retrospective study. A total of 32 cystic masses from January 2018 to
December 2019 were selected. The images of conventional Ultrasound (US) and CEUS were confirmed
via surgical pathology. Routine US was used to observe the location, shape, size, boundary,
cyst wall, internal echo, and blood supply of each cystic mass. CEUS observed contrast enhancement
of the cyst wall, cystic septa, and solid nodules of cystic masses.

Results:

There were 26 cases of CRCC, 5 cases of renal cysts, and 1 case of renal tuberculosis. The
enhancement pattern, degree of enhancement, and pseudocapsular sign by CEUS in benign and malignant
masses had statistically significant differences (P<.05). In the diagnosis of CRCC, the sensitivity,
specificity, accuracy, positive predictive value, and negative predictive value were 92.3%,
83.3%, 90.6%, 96.0%, and 71.4% for CEUS; 57.6%, 66.7%, 59.3%, 88.2%, and 26.7% for conventional
US, respectively. CEUS had a higher sensitivity and accuracy than the conventional US
(P<.05), although the diagnostic specificity, positive predictive value and negative predictive value
of the two methods were not significantly different (P>.05).

Conclusion:

CEUS is more accurate in the diagnosis of renal cystic masses, and it can be used as
an effective imaging method.
In Silico Approach to Predict the SARS-COV2 Derived Candidate MiRNAs as a Potential Antiviral Therapy
Authors: Kavousipour Soudabeh , Mohammadi Shiva , Eftekhar Ebrahim , Jalili Sajad , Arabizadeh Elham , Mokaram Pooneh , Barazesh Mahdi , Moosavy Seyed Hamid
Published: July 2021

Background:

The coronavirus disease 2019 (COVID-19) is a contagious disease originating
from Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Previous experimental
studies indicated that during viral infections, viral miRNAs (vmiRNAs) played key roles in
pathogen-host interaction, immune escape, host cell death, and tumorigenesis. MiRNAs are small,
single-stranded RNAs that exist in viruses as well as in animals. Thus, these molecules can play a
pivotal role in viral disease pathogenesis.

Objective:

Since no approved drugs or vaccines currently exist for SARS-CoV-2 and its pathogenic
mechanism is unknown, the present study aimed to explore and propose vmiRNA platforms
as potential antiviral therapeutic agents against SARS-CoV-2. The development of antiviral drugs
to target vmiRNAs may result in the down-regulation of viral virulence genes expression and suppression
of viral proliferation.

Methods:

In this study, to attain insight into the potential role of SARS-CoV-2-derived miRNAs in
viral infections, a set of computational methods was used to scan the SARS-CoV-2 genome, eventually
predicting 13 potential candidate vmiRNAs. Furthermore, the potential genes were predicted
in the human hosts that were the target of these candidate vmiRNAs by applying the mirPath software.

Results:

This study proposed a theory indicating that the predicted vmiRNAs might have a plausible
role in altering human target gene expression, mainly contributing to a viral infectious state, inflammation,
and immune system escape. These vmiRNAs might have therapeutic trends as antiviral
agents against COVID-19 infection.

Conclusion:

The findings offered a reference idea for a supplementary study on miRNA identification
as a drug target and revealed the necessity to increase the understanding of SARS-CoV-2
genome structure for a better combat against the virus.
Ozone Therapy Alleviates Monosodium Urate Induced Acute Gouty Arthritis in Rats Through Inhibition of NLRP3 Inflammasome
Authors: Abdullah Doaa M. , Kabil Soad L.
Published: July 2021

Background:

Gout is a metabolic disease strictly related to hyperuricemia. The associated
intense inflammation and pain are triggered by the deposited monosodium urate crystals (MSU) in
joints. The principal therapeutic strategies of gout involve the control of hyperuricemia and antiinflammatory
medications.

Objectives:

This study aimed to investigate the possible beneficial effects of ozone therapy, a wellknown
antioxidant and an immunomodulator, on gouty arthritis and the underlying mechanisms.

Methods :

Acute gouty arthritis was induced in male albino rats via MSU crystals intra-articular injection
in the ankle joint. The gouty arthritic rats received pre-treatment with ozone, colchicine (as a reference
drug), or their combination.

Results :

The obtained results of ozone therapy showed an obvious reduction in the degree of edematous
ankle swelling, pro-inflammatory cytokines, lipid peroxidation, the nucleotide-binding oligomerization
domain-like receptor containing pyrin domain 3 (NLRP3), procaspase-1, caspase-1, interleukin-
1β synovial tissue levels with an enhancement of antioxidant defense system. Additionally, ozone
therapy significantly attenuated the histological derangements in gouty arthritic rats.

Conclusion :

This study suggests that ozone is able to treat gouty arthritis and reducing synovial injury
through an anti-inflammatory effect as well as antioxidant activity.
Nanoantioxidant/Antioxidant Therapy in 2019-nCoV: A New Approach to Reactive Oxygen Species Mechanisms
Authors: Jouzdani Ali Fathi , Heidarimoghadam Rezvan , Hazhirkamal Maryam , Ranjbar Akram
Published: July 2021

The COVID-19 pandemic has caused serious concerns for people around the world. The
COVID-19 is associated with respiratory failure, generation of reactive oxygen species (ROS), and the
lack of antioxidants among patients. Specified ROS levels have an essential role as an adjuster of immunological
responses and virus cleaners, but excessive ROS will oxidize membrane lipids and cellular
proteins and quickly destroy virus-infected cells. It can also adversely damage normal cells in the
lungs and even the heart, resulting in multiple organ failures. Given the above, a highly potent antioxidant
therapy can be offered to reduce cardiac loss due to COVID-19. In modern medicine, nanoparticles
containing antioxidants can be used as a high-performance therapy in reducing oxidative stress in
the prevention and treatment of infectious diseases. This can provide a free and interactive tool to determine
whether antioxidants and nanoantioxidants can be administered for COVID-19. More research
and studies are needed to investigate and make definitive opinions about their medicinal uses.
Eco-Friendly Intracellular Biosynthesis of CdS Quantum Dots Using Pseudomonas aeruginosa: Evaluation of Antimicrobial Effects and DNA Cleavage Activities
Authors: Öcal Necip , Ceylan Ahmet , Duman Fatih
Published: July 2021

Background:

Intracellular biosynthesis of Quantum Dots (QDs) based on microorganisms offers a green alternative and eco-friendly for the production of nanocrystals with superior properties. This study focused on the production of intracellular CdS QDs by stimulating the detoxification metabolism of Pseudomonas aeruginosa.

Methods:

For this aim, Pseudomonas aeruginosa ATCC 27853 strain was incubated in a solution of 1mM cadmium sulphate (CdSO4) to manipulate the detoxification mechanism. The intracellularly formed Cd-based material was extracted, and its characterization was carried out by Transmission Electron Microscopy (TEM), X-Ray Diffraction (XRD), Energy Dispersive X-ray (EDX) and dynamic light scattering (DLS) analyses and absorption-emission spectra.

Results:

The obtained material showed absorption peaks at 385 nm and a luminescence peak at 411 nm, and the particle sizes were measured in the range 4.63-17.54 nm. It was determined that the material was sphere-shaped, with a cubic crystalline structure, including Cd and S elements. The antibacterial and antifungal activities of CdS QDs against eleven bacterial (four Grampositive and seven Gram-negative) and one fungal strains were investigated by the agar disk diffusion method. It was revealed that the obtained material has antibacterial effects on both Grampositive and Gram-negative bacteria. However, cleavage activity of CdS QDs on pBR322 DNA was not detected.

Conclusion:

As a result, it has been proposed that the stimulation of the detoxification mechanism can be an easy and effective way of producing green and cheap luminescent QDs or nanomaterial.
Chronic Kidney Disease (CKD) - A Brand Ambassador/Alarming Bell for
Potentially Inappropriate Medication in Elderly Inpatients
Authors: Sharma Rishabh , Bansal Parveen , Chhabra Manik , Arora Malika
Published: July 2021

Background:

Since the past decade, prevalence of Potentially Inappropriate Medication
(PIM) among elderly inpatients has increased drastically. However, limited data is available on
PIM indicators and PIMs use among the elderly in patients suffering from Chronic Kidney Disease
(CKD).

Objective:

The objective of this study is to determine the prevalence of PIMs in elderly hospitalized
patients with CKD.

Methods:

A cross-sectional study was carried out on 102 patients in a tertiary care hospital. PIMs
were identified using Beers criteria 2019. Chi-square test was used to identify the association between
variables and PIMs use.

Results:

PIMs, as assessed according to AGS updated Beers criteria 2019 was found to be in more
than 68.6% of patients of median age 65 years and 3 diagnoses and 7 days median length of stay.
Most of the patients (47.1%) had ≥4 diagnosis. The most common comorbidities in patient were diabetes
mellitus (n=54) and hypertension (n=55). Most of the subjects (66.7%) were on polypharmacy
(5-9 medications/day) and 25.5% were on a higher level of polypharmacy (>10 medicines/day).
Approximately 90% of the patients were having very low CrCl < 21ml/min (calculated with the
help of Cockcroft- Gault formula). A significant association between PIM use and an increased
number of diagnoses, polypharmacy or high-level polypharmacy, was observed.

Conclusion:

The prevalence of PIMs in elderly inpatients suffering from CKD is quite high. The
study clearly indicates negligence/ lack of awareness amongst physicians leading to increase in
PIM use. Authors propose that the CKD patients should attract special attention of physician and
should be treated as brand ambassadors/alarming bell for PIM use.
Direct Synthesis of Formic Acid from Carbon Dioxide by Hydrogenation
Over Ruthenium Metal Doped Titanium Dioxide Nanoparticles in Functionalized
Ionic Liquid
Authors: Srivastava Vivek
Published: July 2021

Background:

Presently worldwide manufacturing of formic acid follows the permutation
of methanol and carbon monoxide in presence of a strong base. But due to the use of toxic CO
molecule and easy availability of CO2 molecule in the atmosphere, most of the research has been
shifted from the conventional method of formic acid synthesis to direct hydrogenation of CO2 gas
using different homogenous and heterogeneous catalysts.

Objective:

To develop reaction protocol to achieve easy CO2 hydrogenation to formic acid using
Ionic liquid reaction medium.

Methods:

We used the sol-gel method followed by calcination (over 250oC for 5 hours) to synthesize
two types of ruthenium metal-doped TiO2 nanoparticles (with and without ionic liquids), namely
Ru@TiO2@IL and Ru@TiO2. We are reporting the application NR2 (R= CH3) containing imidazolium-
based ionic liquids not only to achieve a good reaction rate but also to get agglomeration
free ruthenium metal-doped TiO2 nanoparticles along with easy product isolation due to the presence
of NR2 (R= CH3) functionality in ionic liquid structure. We synthesized various NR2 (R=
CH3) functionalized ionic liquids such as 1-Butyl-3-methylimidazolium Chloride, 1,3-di(N,Ndimethylaminoethyl)-
2-methylimidazolium trifluoromethanesulfonate ([DAMI][TfO]), 1,3-di(N,Ndimethylaminoethyl)-
2-methylimidazolium bis (trifluoromethylsulfonyl) imide ([DAMI][NTf2])
and 1-butyl-3-methylimidazolium chloride ionic liquids which were synthesized as per the reported
procedure.

Results:

We easily developed two types of Ru metal-doped TiO2 nanoparticles using the sol-gel
method. After calcination, both Ru@TiO2@IL (3.2 wt% Ru), and Ru@TiO2 (1.7 wt% Ru) materials
were characterized by XRD, FTIR, TEM, ICP-AES, EDS, and XANES analysis. After understanding
the correct structural arrangement of Ru metal over TiO2 support, we utilized both
Ru@TiO2@IL (3.2 wt% Ru) and Ru@TiO2 (1.7 wt% Ru) the materials as a catalyst for direct hydrogenation
of CO2 in the presence of water and functionalized [DAMI] [TfO] ionic liquid.

Conclusion:

Here we demonstrated the preparation and characterization of TiO2 supported Ru
nanoparticles with and without ionic liquid. After understanding the correct morphology and physiochemical
analysis of Ru@TiO2@IL (3.2 wt% Ru), and Ru@TiO2 (1.7 wt% Ru) catalysts, we examined
their application in CO2 reduction and formic acid synthesis. During the optimization, we
also noticed the significant effect of functionalized [DAMI] [TfO] ionic liquid and water to improve
the formic acid yield. Lastly, we also checked the stability of the catalyst by recycling the
same till the 7th run.
Study on Automatic Tracking Method of Marking Points in Sports Image Sequence
Authors: Pan Cong Hua , Dhiman Gaurav
Published: July 2021

Background:

The effect of teaching and training in physical sports is improved by the
sports demonstration system. The two-dimensional sports demonstration system is widely applied
for the training of athletes. In accurate motion positioning, there exists a certain visual deficiency
and the two-dimensional sports demonstration system is analyzed by kinematics.

Methodology:

Aiming at the problems in the real-time tracking of fast-moving targets in sports images,
an automatic tracking method of sports images based on the registration of landmark points of
the passive optical motion capture system is proposed. Moreover, it aims to build a human model
and divide the human model into several limb segments; find the corresponding relationship between
the first frame of motion data and template data to complete the first frame of motion data
registration; based on the smallest non-rigid deformation and point set matching error, find the corresponding
relationship between the current frame of motion data and the previous frame of registered
motion data; through the mark points, follow up to complete the registration process of the
marker.

Results:

Experiments show that the average processing accuracy of this algorithm can reach over
85% and the processing time of a single frame of motion data is t<1/60s, which can meet real-time
requirements.

Conclusion:

The multi-point set least-squares matching algorithm is used to rigidly correct the registered
landmark data. No manual intervention is required for the entire mark registration process.
Soporte matemático para el ingreso a la universidad
Authors: Jara Riofrío Marco
Published: July 2021

En el documento se presenta, una guía práctica de conocimientos y su aplicación, el cual es una iniciativa para proporcionar a los estudiantes herramientas necesarias para lograr una carrera universitaria exitosa, y así disminuir la deserción, por no contar con los conocimientos básicos que debieron adquirir durante el bachillerato
Apropiación de las TIC en la docencia universitaria: Una mirada desde el pensamiento complejo
Authors: Colina Vargas Alejandra Mercedes
Published: July 2021

Los constantes cambios hacen evidencia del “vivir” lo actual, del aquí y ahora, del entender la globalización, la tecnología y el contexto que nos rodea, instando a una comprensión que se adapte al entorno desde donde se desarrollan, con especial atención, las instituciones de educación universitarias. Es sobre este entorno socioeducativo cambiante por lo que se presenta el reto de enfocar los nexos del quehacer docente con el todo de la enseñanza y el aprendizaje a favor del desarrollo humano. Es sobre estas consideraciones el cómo observo el devenir de este libro, que nace no para cumplir con requisitos académicos de grado, sino para reflejar la genuina oportunidad de avanzar en el conocimiento sobre la Apropiación de las Tecnologías de Información y Comunicación (TIC) en la docencia universitaria, que de manera persistente su autora continuó investigando, a pesar de las circunstancias adversas, inestables y complejas de la vida misma. Así, de manera síncrona a los desafíos que imprimen las TIC en la educación, su gestora concentró recursos y esfuerzos suficientes para develar información relevante que comprendió con una lente distinta y compleja, donándonos -a nosotros los lectores-, su perspectiva investigada, por agobiante y confusa que pudiera haberse encontrado la propia autora.
Herramental de lectura y escritura académica
Authors: Cedeño Viteri Narcisa Beatriz , Villavicencio Bellolio Piedad Mercedes
Published: July 2021

Pensar la escritura como un proceso, es asumirla como una actividad por momentos, por etapas con pasos determinados o múltiples versiones hasta llegar al anhelado producto. Los documentos académico-científicos como productos de distintos tipos deben ser presentados con las características del estilo pertinente, sin embargo, para el estudiante universitario no es fácil, puesto que la escritura no es la simple transcripción de ideas o de saberes, sino un complejo proceso en íntima relación con la lectura. Lo que se lee se convierte en conocimiento a través de la lectura y puede ser utilizado en la escritura según un propósito o intención comunicativa. Entonces la lectura es requisito para previo para que fluyan las ideas alrededor del tema, se amplíe pensamiento se amplíe y se organice la información que constituirá el texto.
El desarrollo de habilidades blandas desde edades tempranas
Authors: Ortega Santos Carlos Ernesto
Published: July 2021

El texto que ahora pongo a disposición de los lectores constituye una síntesis del trabajo de investigación desarrollado, durante más de tres años de análisis documental, aplicación de encuestas, realización de experimentos y desarrollo de entrevistas a Docentes experimentados para lograr la elaboración de una estrategia favorecedora del desarrollo de habilidades blandas desde edades tempranas. Durante las páginas del texto se aborda el tratamiento al aprendizaje informal, dentro y fuera del aula, y la influencia de la familia; así como del entorno, durante el proceso formativo, lo cual se analiza teniendo en cuenta el impacto de las tecnologías de la información y las comunicaciones en el aprendizaje. La estrategia fue defendida con éxito ante el tribunal de Ciencias de la Educación de la Universidad de La Habana, Cuba, en diciembre de 2016.
La consolidación de la educación: Derecho humano y deber del estado
Authors: Alcívar Trejo Carlos , Calderón Cisneros Juan Tarquino , Aguirre Jiménez Silvia , Domínguez Benavide Alejandro A. , Alfonso Caveda Duniesky , Blanc Pihuave Glenda , St. Omer Navarro Vilma
Published: July 2021

En el presente libro se abordará una revisión actualizada sobre la importancia del reconocimiento del derecho a la educación, como un deber ineludible del estado, con respecto a su cumplimiento, de nuevos paradigmas en los procesos académicos en la escuela, el colegio en correlación a una vida universitaria e institucional sobre la calidad en la Educación, su impacto y grado de pertinencia, con la validación de los indicadores sociales clásicos en los contextos globales y nacionales, desde la perspectiva de la relevancia internacional que, en estos momentos goza la formación de un modelo educativo adoptado en nuestro entorno, pero de las que aún no existe una amplia gama de estudios que avalen algunas de las intuiciones que se tienen sobre ellas.
Teleworking and lost work during the pandemic: new evidence from the CPS
Authors: Dey Matthew , Frazis Harley , Piccone Jr David S. , Loewenstein Mark A.
Published: July 2021

To measure the effects of the coronavirus disease 2019 pandemic, the U.S. Bureau of Labor Statistics added questions to the Current Population Survey, the main U.S. labor force survey, starting in May 2020. This article analyzes the results from questions asking people (1) whether they teleworked because of the pandemic and (2) whether they were unable to work because their employers closed or lost business because of the pandemic. We use the data on telework to refine work completed earlier in the pandemic that classified occupations on their suitability for telework. We then apply the revised classification to examine trends in telework and the extent to which working in an occupation suitable for telework shields workers from unemployment. Our results show that the pandemic resulted in a large increase in teleworking, with 33 percent of U.S. workers reporting teleworking because of the coronavirus in the period May-June 2020, before declining to a still substantial 22 percent in the fourth quarter. Rates of lost work varied widely both by an occupation’s suitability for telework and by demographic category.
Evaluating Quality, Usability, Evidence-Based Content, and Gamification Features in Mobile Learning Apps Designed to Teach Children Basic Life Support: Systematic Search in App Stores and Content Analysis
Authors: Fijačko Nino , Masterson Creber Ruth , Gosak Lucija , Štiglic Gregor , Egan Dominic , Chaka Brian , Debeljak Nika , Strnad Matej , Skok Pavel
Published: July 2021

Background

Globally, 3.7 million people die of sudden cardiac death annually. Following the World Health Organization endorsement of the Kids Save Lives statements, initiatives to train school-age children in basic life support (BLS) have been widespread. Mobile phone apps, combined with gamification, represent an opportunity for including mobile learning (m-learning) in teaching schoolchildren BLS as an additional teaching method; however, the quality of these apps is questionable.

Objective

This study aims to systematically evaluate the quality, usability, evidence-based content, and gamification features (GFs) of commercially available m-learning apps for teaching guideline-directed BLS knowledge and skills to school-aged children.

Methods

We searched the Google Play Store and Apple iOS App Store using multiple terms (eg, cardiopulmonary resuscitation [CPR] or BLS). Apps meeting the inclusion criteria were evaluated by 15 emergency health care professionals using the user version of the Mobile Application Rating Scale and System Usability Scale. We modified a five-finger mnemonic for teaching schoolchildren BLS and reviewed the apps’ BLS content using standardized criteria based on three CPR guidelines. GFs in the apps were evaluated using a gamification taxonomy.

Results

Of the 1207 potentially relevant apps, only 6 (0.49%) met the inclusion criteria. Most apps were excluded because the content was not related to teaching schoolchildren BLS. The mean total scores for the user version of the Mobile Application Rating Scale and System Usability Scale score were 3.2/5 points (95% CI 3.0-3.4) and 47.1/100 points (95% CI 42.1-52.1), respectively. Half of the apps taught hands-only CPR, whereas the other half also included ventilation. All the apps indicated when to start chest compressions, and only 1 app taught BLS using an automated external defibrillator. Gamification was well integrated into the m-learning apps for teaching schoolchildren BLS, whereas the personal and fictional, educational, and performance gamification groups represented most GFs.

Conclusions

Improving the quality and usability of BLS content in apps and combining them with GFs can offer educators novel m-learning tools to teach schoolchildren BLS skills.
Correction: Global Changes and Factors of Increase in Caloric/Salty Food Intake, Screen Use, and Substance Use During the Early COVID-19 Containment Phase in the General Population in France: Survey Study (Preprint)
Authors: Rolland Benjamin , Haesebaert Frédéric , Zante Elodie , Benyamina Amine , Haesebaert Julie , Franck Nicolas
Published: July 2021

UNSTRUCTURED

REMOVE
A Retrospective Study of Bacteriology and Antibiotic Sensitivity Pattern of Post Operative Surgical Site Infections in Orthopedics
Authors: Rajani R. , Veerabhadra J.
Published: July 2021

Surgical Site infection (SSI) is one of the most common post-operative complications and causes significant post-operative morbidity and mortality. The global estimates of SSI have varied from 0.5% to 15%, studies in India have consistently shown higher rates ranging from 23% to 38%1. The aim of the study was to know the etiological bacterial agents causing SSI and their antimicrobial susceptibility pattern. This retrospective study included 69 patients who developed Post-operative wound infections (SSI) during the 1-year period from April 2019 to March 2020. An analysis of SSI occurrence, the organisms isolated and antibiotic sensitivity pattern results was made. In overall surgeries conducted during the study period in orthopedics department at our institute, 69 cases were clinically diagnosed of having SSIs, including 51 males and 18 females with the mean age of 39.2 years. Out of the total 69 samples, 6 (8.69%) yielded no bacterial growth and among the rest 63 samples, Staphylococcus aureus 21 (30.43%) was the most common organism isolated. The other organisms isolated were Klebsiella pneumonia 13 (18.84%), Pseudomonas 11 (15.94%), Escherichia coli 5 (7.24%), Proteus species 3 (4.34%) and Acinetobacter species 3 (4.34%). Mixed isolates were obtained in 2 (11.9%) specimens. Bacteriological and antibiotic susceptibility study is an important tool to treat infection timely and effectively in-turn minimizing untoward long term sequelae of surgical site infections.
AN OVERVIEW OF AMENORRHEA
Authors: Anu Prasad N
Published: July 2021

Amenorrhea is defined as the nonappearance of menstruation in women. Amenorrhea may be divided in to primary and secondary amenorrhea. Primary amenorrhea is caused due to anatomical, genetic, nutritional and other endocrine defects. Anatomical causes includes distal obstruction, MRKH and AIS. Primary Ovarian Insufficiency is the foremost causes of primary amenorrhea. The frequent causes of secondary amenorrhea are pregnancy. Other causes of secondary amenorrhea include PCOD, functional hypothalamic amenorrhea, POI. Depending upon the causes, the amenorrhea affected women should experiences the symptoms like hair loss, acne, excess facial hair, milky nipple discharge, etc along with the absence of menstruation. Amenorrhea is diagnosed using the patient laboratory data, pelvic ultrasonography, hysteroscopy. Management of amenorrhea is based upon its causes. PCOS patients is usually treated with regular exercise and healthy food diet. Amenorrhea is initially treated with hormonal therapy followed by hysterectomy. Regular intake of vitamin D and calcium is also recommended.
EFFECT OF MATRIX RHYTHM THERAPY ON A CHRONIC CASE OF MEDIAN NERVE ENTRAPMENT AT THE ELBOW JOINT
Authors: Deolankar Apurva
Published: July 2021

Pronator teres syndrome is a rare condition, in which compression on the median nerve occurs at the elbow joint. It is a very rare condition compare to carpel tunnel syndrome. Compression can cause pain and numbness in the hand. The most common cause of pronator teres syndrome is compression of the median nerve in between the two belley’s of pronator teres muscles. In the case of advanced disease, the pain and numbness can be managed by prednisolone injections. Some of the literature shows massage therapy also works on relieving the symptoms. Matrix rhythm therapy (MaRhyThe) has shown to be beneficial in the treatment of pain and movement disturbances. Matrix rhythm therapy is invented by Dr.Randoll from Germany for the treatment of pain and does not have side effects. The case report was aimed to evaluate the effect of matrix rhythm therapy on pronator teres syndrome which lasted for 60 minutes each day for 3 days and was divided into 3 zones along with other physiotherapy interventions. It showed a positive result in pronator teres syndrome as the pain was reduced on the 3rd day of the session.
POST HYSTERECTOMY PHYSIOTHERAPEUTIC PROTOCOL FOR CORE MUSCLES AND PELVIC FLOOR MUSCULATURE STRENGTHENING IN CASE OF ADENOMYOSIS
Authors: Choubisa Chitrakshi A.
Published: July 2021

Adenomyosis is an important gynecological condition. It is considered a benign uterine disorder that shows a pathological demonstration of the endometrial gland and stroma in the uterine myometrium. A 42 years old female patient presented with excessive bleeding during menses and irregular menstrual cycle with dysmenorrhea, for 7-8 months. The patient complains of pain for 7-8 months in the lower abdomen region, in the iliac fossa on both left and right side, and is insidious in onset. The patient went to a private hospital where she got diagnosed with adenomyosis and suggest removal of the uterus. The investigation was done which includes CBC, KFT, LFT, and USG abdomen and pelvis which reviled that patient is having Adenomyosis. Vaginal hysterectomy is the least invasive type of hysterectomy, which is having lesser costs and risks which can also be done in women having uterus weighing more than 280g. For managing postoperative complication of hysterectomy various physiotherapy intervention could be given which includes pelvic strengthening exercises, core strengthening, breathing exercises, and yoga poses. The study concluded that hysterectomy may result in post-surgical manifestations which can be effectively managed by early physiotherapy intervention which impacts on quality of life of the patient.
EFFECT OF PROPRIOCEPTIVE TRAINING IN ACL TEAR WITH MENISCAL INJURY
Authors: Kharche Vrushali
Published: July 2021

Anterior cruciate ligament tear and meniscal tear are the most common injuries which are associated with each other. It has an impact on knee stability which will cause impairment in balance. A 22-year female student met with a road traffic accident during which she had a sudden blow on her left knee which gave her immediate symptoms of pain and instability in the knee. She visited an orthopedician and he suggested for surgery but she didn’t undergo surgery and started physiotherapy treatment. In this patient, we mainly focus on proprioceptive training which was effective in improving balance and this will also give early recovery and improves the quality of life. Proprioceptive training shows a significant impact on patient’s recovery.
ANTHELMINTIC, ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY OF DIFFERENT PART OF INDIAN ORIGIN SALVADORA PERSICA
Authors: Kumar Dharmendra
Published: July 2021

Nowadays, Herbal products are attracting the whole population of the world because of their safety features. The present study aimed to reveal the phytochemical compositions, anthelmintic activity, antioxidant and antimicrobial potential of Salvadora persica leaves extract in different extraction solvent systems. Shade dried leaves of Salvadora persica were extracted in chloroform, ethyl acetate, methanol, ethanol, and water using the modified fractional maceration method. These extracts were analyzed for their phytochemical, anthelmintic activity, antioxidant and antimicrobial potential. The antioxidant activity was done using DPPH and H2O2 radical scavenging method. While the antimicrobial potential was analyzed using the disc diffusion method. Anthelmintic activity was determined against Indian earthworms (Eiseniafetida).The highest percentage yield of extract was found in the hydro solvent extraction system. The DPPH radical scavenging was found 67.3% (lowest) and 99.07% (highest), (dose100µg/ml), in SPLEC and SPLEW respectively. The highest antimicrobial activity was found in SPLEE (200µg/ml and 100µg/ml) i.e. 6 mm and 4 mm zone of inhibition against E.coli while 5mm and 3mm again B. subitilis respectively. All extract fractions of Salvadora persica exhibited anthelmintic activity but less than standard drug albendazole. Based on our findings, we were concluded that leaves of Salvadora persica have an anthelmintic effect good antioxidant and antimicrobial potential so their consumption may exert a beneficial effect on human and animal health as well
Optimization of channels and I-shaped bended closed profiles with tubular shelves from sheets of different thicknesses
Authors: Marutyan Alexander S.
Published: July 2021

The continuation of optimization of channels and I-beams bent closed profiles (BCP) with tubular flanges made of rolled sheet of different thicknesses is presented. Such profiles are intended for light steel thin-walled structures (LSWS), which are distinguished by high technical and economic indicators and massive demand in industrial and civil construction, which confirms the relevance of their further development. The main results of the calculation of the optimal bending arrangement of composite sections of I-beams from sheet blanks of different thicknesses, including channel-type BCPs unified in terms of optimal parameters, are also presented. The aim of the study is to show that the characteristics of the LSWS can be further improved by shaping profiles, combining straight and round outlines of closed and open contours in a composite section. Methods. By means of experimental design studies, solution of optimization problems and variant design of I-profiles, their composite sections from sheet blanks of different thicknesses, including blanks of channel profiles, have been refined. The originality of channels and I-shaped BCP has been confirmed by patent examination. Results. The I-shaped BCP consists of two tubular shelves and one double thickness wall. Calculation of the optimal layout of an I-shaped BCP made of rolled sheet of different thicknesses for bending showed that the bearing capacity is limited by the ratio of the thickness of the flanges and the wall of its composite section. In particular, when the thickness of the flanges is 2 times the wall thickness, the strength is maximum at a ratio of width to height of 1/11, and when the thickness of the flanges is 0.6 times the wall thickness, the strength is maximum at a ratio of 1/3.3. With the ratios of the width and height of I-shaped BCP of 1/2.68...1/3 and channel-type BCPs of 1/5.36...1/6, their composite sections should be optimally assembled from standardized blanks.