bluuebunny/crossref_metadata_2025 huggingface dataset:
Personálna, spoločenská a profesijná príprava kadetov AOS prostredníctvom výuky religionistiky
Authors: Huďa Tomáš
Published: September 2024

The presented study was created as a contribution that was presented at the international scientific conference entitled New trends of professional training in the armed forces and security forces held on May 23, 2024 at the Academy of the Armed Forces of General Milan Rastislav Štefánik in Liptovský Mikuláš. It goes without saying that it does not cover the entire issue in the field, which is extremely extensive and complex. It offers an overview and basic general information about the science of religious studies. Subsequently, it addresses specific reasons why the spiritual essence of a person, his religiosity and the epistemology of spiritual realities in the personal, social and professional modality of a military professional should not be forgotten when preparing future officer-leaders.
Rozvoj kompetencií koordinátorov podporných programov
Authors: Czirák Pavel
Published: September 2024

The article is informative in nature. It acquaints with a brief history of introducing social work into the Armed Forces of the Slovak Republic. It informs about the competence of the coordinators of support programs and outlines in more detail the activities it will provide under each agenda. It describes the factors influencing the creation of preparation and further education of coordinators of support programs and lists the main actors of education of these functions in the conditions of the Armed Forces of the Slovak Republic.
Aktuálny pohľad na vývoj v oblasti odmeňovania policajtov
Authors: Ivančík Radoslav
Published: September 2024

Police officers are a unique and irreplaceable resource, essential for the successful functioning of a police organization – an organization involved in ensuring the security of the state and its residents. They are police officers who, with their work, activity, initiative, commitment, and dedication, set and determine not only the strategy and goals of the police organization, but also ensure the fulfillment of its mission and the achievement of the set goals. The effort for the successful and efficient functioning of the police organization and the achievement of the desired results requires the constant development of human resources in the form of members of the Police Force, as well as their direction, motivation, and support for the active and high-quality performance of official tasks. They should also be adequately rewarded for this active and high-quality performance of tasks. For this reason, the primary goal of this scientific contribution is the analysis of the current development of the remuneration of members of the Police Force - the security force ensuring internal security, order and protection of the lives, health, and property of the inhabitants - in the context of the development of key indicators of economic development in the Slovak Republic over the last ten years.
Formulation and Assessment of Polyherbal Candies for Soothing Cough and Sore Throat
Authors: S. Shaikh Junaid , D. Barhate Shashikant
Published: September 2024

Hard cough drops or small candies are intended to be taken orally and melted slowly to relieve sore throats caused by colds, cough and flu. These treats are made with natural ingredients to help relieve coughs. Plant substances and natural medicines are currently attracting great interest in their flexible application, as medicinal plants are the richest source of bioactive substances used in traditional and modern medicines. This article is based on the formulation of medicated tri-herbal candy containing natural ingredients and its evaluations such as physicochemical properties, weight uniformity, stability test, disintegration test, and identification test. All three formulations passed the tests according to all parameters, but formulation number 2 is particularly acceptable due to its sweetness.
Thực trạng quản lý hoạt động phối hợp giữa nhà trường và gia đình trong giáo dục học tập cho học sinh ở các trường trung học cơ sở huyện Bình Tân, tỉnh Vĩnh Long
Authors: Hà Thanh Bình
Published: September 2024

Quản lý hoạt động phối hợp giữa nhà trường và gia đình trong giáo dục học tập cho học sinh đóng vai trò hết sức quan trọng nhằm kết nối chặt chẽ giữa nhà trường và gia đình để cung cấp cho học sinh sự hỗ trợ sâu sắc trong lẫn ngoài lớp học. Bài viết trình bày thực trạng quản lý hoạt động phối hợp giữa nhà trường và gia đình trong giáo dục học tập cho học sinh ở các trường trung học cơ sở huyện Bình Tân, tỉnh Vĩnh Long, thông qua điều tra bằng bảng hỏi từ cán bộ quản lý, giáo viên và cha mẹ học sinh của 05 trường trung học cơ sở ở huyện Bình Tân. Kết quả khảo sát được xử lý số liệu theo thang đo 5 mức độ để tính giá trị phần trăm; tính điểm trung bình; độ lệch chuẩn và xếp hạng. Kết quả khảo sát cho thấy, mặc dù công tác quản lý hoạt động phối hợp giữa nhà trường và gia đình trong giáo dục học tập cho học sinh ở các trường trung học cơ sở huyện Bình Tân, tỉnh Vĩnh Long trong thời gian qua được các nhà trường quan tâm nhưng vẫn còn những hạn chế bất cập cần khắc phục. Đây là cơ sở thực tiễn để đề xuất các giải pháp nâng cao chất lượng quản lý hoạt động phối hợp giữa nhà trường và gia đình trong giáo dục học tập cho học sinh ở các trường trung học cơ sở huyện Bình Tân, tỉnh Vĩnh Long trong thời gian tới.
Application of experimental-statistical modelling for heat treatment of polymineral clays introduced into cement composites
Authors: Nizina Tatyana , Volodin Vladimir , Matyakubov Khasan
Published: September 2024

The article presents a method of producing an active mineral additive by firing polymineral clay. The authors show the possibility of obtaining cement composites with increased strength characteristics both due to the introduction of clay additive and due to the optimisation of the clay firing conditions. The authors used experimental and statistical modelling techniques to determine the appropriate clay firing conditions to produce an active mineral additive for cement composites.
An Investigation of Cooperative Learning Strategies in Improving Students' Comprehension Skills in the Context of English as a Foreign Language (EFL)
Authors: Ahmed Awwad Othman Abdelaziz , AbdAlgane Mohammed
Published: September 2024

The objective of this study was to enhance the reading comprehension abilities of EFL students by implementing cooperative learning strategies. The study aimed to address the following primary research question: What is the influence of cooperative learning on enhancing the reading comprehension skills of EFL students? The study included a total of 70 students from the first and second levels of the Department of English and Literature at the Ar Rass campus of Qassim University in Saudi Arabia. We conducted the study over a three-week period in two classes: the control group consisted of 35 female students (N = 35), while the experimental group also included 35 female students (N = 35). The experimental group received instruction through cooperative learning strategies, whereas the control group received instruction through a standard teacher-centered strategy. To address the fact-finding investigation of the study, we employed a pre- and post-test tool to assess reading comprehension skills. This test specifically aimed to identify the levels of literal and inferential comprehension. We employed the t-test to determine the statistical divergence between the average scores of the two groups. This study demonstrated the beneficial influence of cooperative learning approaches on the enhancement of reading comprehension skills among first- and second-level students in the Department of English and Literature. We strongly recommend cooperative learning practices to improve the reading skills of EFL learners.
Volleyball Related Injuries in Adolescents: A Decade of Data
Authors: Jandhyala Aaditya , Elahi Jasra , Ganti Latha , McAuley Darren
Published: September 2024

Objectives

Playing sports is crucial to adolescents as a source of entertainment, a factor in improving mental health, and a way to promote physical development. However, sports, including volleyball, have an inherent risk of causing injuries to its players. The objective of this study is to determine the most common locations, types, and outcomes of volleyball injuries in adolescent athletes so that more people are aware of how these injuries occur. This would encourage volleyball athletes to be more mindful of these injuries when playing.

Methods

The National Electronic Injury Surveillance System (NEISS) was used to analyze injuries in adolescents (ages 10-19) that occurred due to volleyball between the years 2013 and 2022.

Results

Approximately 347,395 volleyball injuries occurred in adolescents between 2013 and 2022, with the median age of patients being 15 years old. 274,003 patients were female (78.9%) while 73,392 patients were male (21.1%). 59,530 had injuries in the head or neck (17.1%), 141,660 in the lower extremities (40.8%), and 119,230 in the upper extremities (34.3%). 151,364 patients had sprains or strains (43.6%), 35,760 had fractures (10.3%), 36,804 had contusions or abrasions (10.6%), and the rest of the patients had other injuries. 342,567 patients were treated and released (98.6%), 2049 patients were left without being seen (0.6%), and 1648 patients were hospitalized (0.5%).

Conclusions

This study shows that volleyball players are most vulnerable to getting sprains, strains, fractures, or bruises in the upper or lower extremities. While there are more injuries in adolescent females, this is likely because a majority of volleyball players between the ages of 10 and 19 are female. Further study may be done to identify how volleyball causes these injuries in an effort to prevent them.
Pengaruh Gaji dan Motivasi Kerja terhadap Produktivitas Guru SMA Della Strada
Authors: Dhana Agnes , Iskandar Donant Alananto
Published: September 2024

The aim of this research is to determine the effect of salary and work motivation on teacher productivity.The conceptual model is a summary of a thought, the relationship between the variables. In this research, the researcher used variables namely, the effect of salary, work motivation, and productivity. With the object of research, namely SMA Della Strada teacher. This study uses a quantitative method with saturated sampling technique. Data collection is done by distributing questionnaires via google form to 30 respondents who will be processed using SPSS 25.Based on the results of the research, the following conclusions can be drawn as follows: There is a significant positive effect of salary on teacher productivity at Della Strada High School which means that the more appropriate the salary given, the productivity will increase and vice versa. There is a significant positive effect of motivation on teacher productivity at Della Strada High School which means that the more appropriate the motivation given, the productivity will increase and vice versa. There is a significant effect of motivation on teacher productivity at SMA Della Strada. Salary and motivation variables can affect productivity by 61.2%.
DOENÇA DE ALZHEIMER: COLESTEROL ALTO É ASSOCIADO A ESCORES MAIS BAIXOS NO MINIEXAME DO ESTADO MENTAL (MEEM)
Authors: Komatsu C , Komatsu RS
Published: September 2024

Objetivo: Investigar a associação entre as taxas de colesterol total/lipoproteína de baixa densidade (LDL) e escores no miniexame do estado mental (MEEM) em pacientes com doença de Alzheimer (DA). Método: Cento e cinquenta e quatro pacientes ambulatoriais com o diagnóstico de DA, de acordo com os critérios propostos por NINCDS-ADRDA (2011), acompanhados em um hospital universitário público, tiveram suas taxas de colesterol e seus escores no MEEM avaliados. Conclusão: Noventa pacientes (58,44%) apresentaram colesterol alto (colesterol total > 189 mg/dl e/ou LDL > 129 mg/dl) e 64 (41,56%), índice de colesterol normal (colesterol total < 190 mg/dl e/ou LDL < 130 mg/dl). Do grupo com colesterol alto, 10 pacientes (11,11%) apresentaram comprometimento cognitivo grave (MEEM < 10), 50 (55,55%), comprometimento cognitivo moderado (MEEM = 10-20) e 30 (33,34%), comprometimento cognitivo leve (MEEM > 20). Do grupo com taxa de colesterol normal, cinco pacientes (7,81%) apresentaram comprometimento cognitivo grave, 19 (29,69%), comprometimento cognitivo moderado e 40 (62,5%), comprometimento cognitivo leve. Ambos os grupos, com colesterol alto e taxa de colesterol normal, tinham, em média, o mesmo nível de escolaridade: 2,91 e 3,42 anos, respectivamente. Nesta amostra de pacientes com DA, portanto, o colesterol alto é associado a escores menores no MEEM, quando comparado com a taxa de colesterol normal.
NÍVEIS SÉRICOS DE BUN E CREATININA EM PACIENTES COM COVID-19 INTERNADOS EM UTI EM UM HOSPITAL DE REFERÊNCIA
Authors: Lopes RJ , Cauz M , Duarte AF , Freitas JI , Perico LL , Suldofski MT
Published: September 2024

Objetivo: Este trabalho pesquisou níveis aumentados de creatinina sérica (> 1,2 mg/ dl) e BUN (> 36 mg/dl) em pacientes com Covid-19 internados em uma unidade de terapia intensiva (UTI) de um hospital em Cascavel, Paraná, buscando compreender se a infecção pelo coronavírus está relacionada com o desenvolvimento de insuficiência renal aguda (IRA). Método: Os dados foram coletados no período de janeiro a março de 2022, por meio de prontuário eletrônico, utilizando o sistema informatizado Tasy. Após o levantamento de dados, eles foram tabulados em planilha Excel (Microsoft Office 2010) para posterior análise. Conclusão: Por meio desta análise, foram coletados resultados de creatinina e BUN de 61 pacientes; a média de idade foi de 62 anos. Desses pacientes, 41% apresentaram creatinina maior do que o valor de referência e 72%, valores aumentados de BUN. A mortalidade foi de 37%, sendo 16% do total de óbitos com a creatinina sérica elevada. A creatinina é um importante biomarcador para avaliar a função renal de pacientes internados em UTI. Considera-se que a ureia sofre maiores influências de fatores extrarrenais e, portanto, a creatinina é um biomarcador mais fidedigno da taxa de filtração glomerular. A Covid-19 pode estar relacionada com o desenvolvimento de IRA, associando-se à maior mortalidade e a um pior prognóstico. Entretanto, são necessárias mais pesquisas com foco em biomarcadores e outros achados laboratoriais que indiquem alterações renais de pacientes infectados pelo coronavírus. Referência: 1. Poloni JAT et al. Insuficiência renal aguda em pacientes com Covid-19. Rev Bras An Clin. 2020; 52(2).
AVALIAÇÃO NOS NÍVEIS SÉRICOS DA ADENOSINA DEAMINASE EM PACIENTES COM DOENÇA PERIODONTAL
Authors: Chielle EO , Füchter SCC , Maciel SFVO
Published: September 2024

Objetivo: A doença periodontal (DP) é uma condição inflamatória que compromete as estruturas de proteção e inserção dentária, porém, ela não se restringe apenas à cavidade bucal, uma vez que afeta negativamente outros sistemas do corpo humano, sendo fortemente associada a várias doenças sistêmicas. O objetivo deste estudo foi avaliar os níveis séricos da adenosina deaminase (ADA) no soro de pacientes com DP e em pacientes saudáveis. Método: Estudo transversal, com análise quantitativa. A atividade da ADA foi avaliada no soro de pacientes com DP e em pacientes saudáveis (25 controles e 57 com DP), sem outras comorbidades que pudessem alterar sua atividade em níveis séricos. A atividade da ADA foi determinada por kit comercial (Ebram Prod ucts Laboratory Ltda®, SP, Brasil) de acordo com a desaminação da adenosina em inosina por via cinética. Os valores foram expressos em U/l. Conclusão: A atividade da ADA no soro não apresentou diferença estatisticamente significativa (p ≥ 0,5), porém apresentou tendência a estar aumentada em pacientes com DP em comparação com os pacientes saudáveis. Apesar de os resultados não apresentarem diferença estatisticamente significativa, este estudo levanta questões relevantes entre a DP e seus efeitos sistêmicos, necessitando de mais pesquisas para avaliar a associação entre a DP e outras doenças. Referências: 1. Bours MJL et al. Adenosine 5’-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Therapeutic. 2006; 112(2): 358-404. 2. Peres MA et al. Oral diseases: a global public health challenge. Lancet (London, England). 2019; 394(10194): 249-60. 3. Sarhat DER et al. The Effect of diabetic patients with chronic periodontitis on serum paraoxonase, adenosine deaminase. 2018; 15(1): 5.
VERIFICAÇÃO DE DESEMPENHO DA DOSAGEM DE NT-PRO BNP NA PLATAFORMA ATELLICA IM SIEMENS®
Authors: Silva LHT , Campos JR , Fernandes AB , Cabral EDL
Published: September 2024

Objetivo: Avaliar o desempenho da dosagem de NT-PRO BNP em comparação com a plataforma Immulite 2000 Siemens®. Método: Foram selecionadas 30 amostras de soro com diferentes níveis de concentração para avaliar o desempenho da metodologia Quimioluminescência no equipamento Atellica IM Siemens®, utilizando o kit PBNP em relação a mesma metodologia no equipamento Immulite kit NTP Siemens®. Realizou-se teste de imprecisão em dois níveis de concentração, utilizando o material de controle Liquicheck Cardiac Markers Plus LT Biorad®. A verificação de métodos foi considerada aprovada quando o erro total nos dois níveis de decisão foi inferior ao máximo permitido pela especificação da qualidade definida pelo laboratório (especificação desejável da variação biológica – Carmen Ricos). Conclusão: Após análise estatística, obtiveram-se os seguintes resultados: coeficiente de correlação de Pearson (R) 0,995; regresão linear entre os Métodos: sistema analítico teste = 1,399 + 1,01 × sistema analítico comparativo; imprecisão no nível 1 de decisão médica (N1): repetibilidade: 1,43%, intralaboratório: 1,49%; imprecisão no nível 2 de decisão médica (N2): repetibilidade: 1,91%, intralaboratório: 2,89%. Imprecisão máxima permitida: 7,5%. Erro total (N1): 2,51%, erro total (N2): 24,13%. Erro total máximo permitido: 19,45%. Estimativa do bias (N1): -0,15%, estimativa do bias (N2): 19,36% – bias máximo permitido: 7,08%. O erro total e a estimativa do bias do nível 2 estão acima do máximo permitido, entretanto, foi realizada a validação clínica dos pacientes para avaliação devido a diferentes valores de referência de acordo com a faixa etária. Após estratificação dos resultados por sexo e idade, não houve mudança na interpretação clínica e na conduta médica. Considerando-se a validação clínica dos pacientes, houve 100% de concordância entre os dados, aprovando-se o kit para uso no equipamento Atellica IM Siemens®.
ESTIMATIVA DE INTERVALOS DE REFERÊNCIA (IR): ÁCIDO ÚRICO EM ADULTOS NO SUDESTE DO BRASIL, FERRAMENTA LAB RI EM MINERAÇÃO DE DATALAKE
Authors: Canali DGR , Lopes ACW , Meira CM , Vieira LMF , Garoli YG , Rodrigues L
Published: September 2024

Objetivo: O ácido úrico (AU) é um metabólito das purinas. Alterações podem ocorrer em doenças, incluindo nefropatias, gota, doenças hematológicas, diabetes e doenças genéticas. Para análise diagnóstica, é fundamental que a interpretação seja baseada em IR adequado para população atendida, o que é um requisito atual do Programa de Acreditação de Laboratórios Clínicos (PALC). O objetivo deste estudo foi avaliar os IR disponibilizados pelo fabricante, utilizando banco de dados de grande laboratório da região sudeste do Brasil. Método: Foram minerados resultados de AU entre janeiro e dezembro de 2021. Incluídos no estudo pacientes > 18 anos, ambulatoriais, analisados na plataforma Siemens com resultados dentro da linearidade. Critérios de exclusão: colesterol total > 200 mg/dl, triglicerídeos > 150 mg/dl, glicemia > 126 mg/dl, ferritina > 300 ng/ ml, creatinina > 1,5 mg/dl e PCR >10 mg/dl no mesmo mês. Utilizou-se a ferramenta LabRI nos tratamentos estatísticos e algoritmos em linguagem R, combinando estatísticas paramétricas, não paramétricas e robustas para exclusão de outliers e valores anormais. Estimar IR e intervalos de confiança (IC) para cada partição. Conclusão: Incluídos 49.706 indivíduos (53% mulheres). Realizada a exclusão de 217 outliers; a média e a mediana permaneceram as mesmas após a exclusão (sexo feminino 4,5 e 4,4 e masculino 6,1 e 6,0, respectivamente). Comparando IR do fabricante (3,7-9,2 mg/dl geral) com estatísticas da população atendida, 96,8% dos homens e 76,2% das mulheres dentro do intervalo. Quanto ao sexo feminino, 23,8% estavam abaixo do limite proposto pelo fabricante e nenhuma paciente acima do percentil 97,5. IR mais apropriados para esta população foram estimados em 2,8-6,7 mg/dl para mulheres e 3,8-8,6 mg/dl para homens. Após definição da ferramenta estatística segura e análise multidisciplinar dos resultados, o IR disponibilizado pelo fabricante foi substituído pelos IRs próprios em duas partições.
VERIFICAÇÃO DO DESEMPENHO ANALÍTICO DOS KITS THROMBIN REAGENT, THROMBOREL® S E DADE® ACTIN FSL NO EQUIPAMENTO SYSMEX® CS-2500
Authors: Nunes JT , Aleixo AS , Tiago LN , Silva RMP , Fernandes AB , Campos JR , Cabral EDL
Published: September 2024

Objetivo: Comparar o desempenho analítico dos kits Thrombin Reagent, Thromborel® S e Dade® Actin FSL Siemens para dosagem do fibrinogênio (FIB), tempo de protrombina (PT) e tempo de tromboplastina parcial ativada (TTPa), respectivamente, no equipamento Sysmex® CS-2500 em relação ao equipamento Sysmex® CA-1500. Método: Um total de 42 amostras colhidas em anticoagulante citrato de sódio foi centrifugado a 3000 rotações por minuto (rpm) em temperatura ambiente, por 10 minutos, para obtenção do plasma. As dosagens foram realizadas no equipamento Sysmex® CA-1500 e imediatamente no equipamento Sysmex® CS-2500, utilizando-se o método coagulométrico. Realizou-se teste de imprecisão com material de controle Siemens®. Para comparação entre os métodos, foram utilizadas amostras em diferentes faixas de decisão clínica. A análise estatística foi realizada em planilha de comparação de métodos, e o analito foi considerado aprovado quando o erro total foi inferior à especificação da qualidade analítica definida pelo laboratório, avaliando-se também a concordância clínica dos resultados. Conclusão: Após análise estatística dos dados, obtiveram-se os seguintes resultados: • FIB – imprecisão nível 1 (246,7 mg/dl): 3,89%; imprecisão nível 2 (79,1 mg/dl): 3,97%; imprecisão máxima permitida (IMP): 8,03%. Erro total nível 1 (180 mg/dl): 7,16%; erro total nível 2 (350 mg/dl): 6,87%; erro total máximo permitido (ETMP): 20,4%. • PT – imprecisão nível 1 (11,8 seg): 1,54%; imprecisão nível 2 (19,7 seg): 1,96%; IMP: 3%. Erro total nível 1 (11,8 seg): 3,75%; erro total nível 2 (19,7 seg): 3,77%; ETMP: 7,91%. • TTPa – imprecisão nível 1 (26,5 seg): 1,2%; imprecisão nível 2 (46 seg): 1,44%; IMP: 2%. Erro total nível 1 (26 seg): 3,02%; erro total nível 2 (40 seg): 5,37%; ETMP: 6,72%. Houve concordância clínica de 100% para os exames FIB e PT e de 97,56% para o TTPa. Conclui-se que os analitos verificados no equipamento CS-2500 foram aprovados por apresentar ETMP inferior à especificação da qualidade analítica definida pelo laboratório.
SOFTWARE IMPLEMENTATION OF DECOMPOSITION METHODS FOR DETERMINING COMPLEX ONE-PARAMETER GENERALIZED INVERSE MOORE-PENROSE MATRICES (I)
Authors: Simonyan S.H. , Melikyan A.V. , Abgaryan H.S.
Published: September 2024

Software implementations of analytical and numerical-analytical decomposition methods for determining complex one-parameter generalized inverse Moore-Penrose mat-rices are presented. Analytical methods are based on the first two Moore-Penrose con-ditions: in both cases the same solution to the problem is obtained, as it should be. Numerical-analytical methods are based on the obtained analytical relations and differential Pukhov transformations. Computational methods are implemented using modern infor-mation technologies, in particular Python programming language, NumPy and SymPy libraries. Software implementations consist of programs for entering the di-mensions and elements of a given matrix, implementation of an analytical method, de-termination of matrix elements derivatives and their values, calculation of matrix discretes and restoration of original matrices, as well as determining pseudo-inverse matrix. In addi-tion, the software implementation of the numerical-analytical method also contains a cus-tom implemented functions for determining the given matrix elements derivatives and for calculating the matrix discretes at the approximation center with a given scaling coeffi-cient. Algorithm flowcharts and Python source codes for all listed programs are presented.
The software implementation is tested on a model example with a square matrix, for which an analytical solution is obtained using two approaches - the determination of the usual inverse one-parameter matrix and the decomposition method for determining the same matrix. This matrix is defined in exactly the same way as numerical-analytical decomposition methods.
Application of thermography in medicine. Part II
Authors: Chochowska Magorzata , Porada Dagmara , Rujna Krzysztof , Kubisz Leszek
Published: September 2024

W pierwszej części artykułu przedstawiono podstawy fizyczne termografii oraz kamer termowizyjnych (detektorów), wykorzystujących detekcję promieniowania cieplnego, które umożliwiają wykrycie zmiany temperatur w różnych częściach ciała ludzkiego, dzięki czemu termografia znajduje zastosowanie w diagnostyce uzupełniającej chorób w wielu dziedzinach medycyny: angiologii, chorobach wewnętrznych, chirurgii estetycznej i rekonstrukcyjnej (co opisano w pierwszej części artykułu), a także w ginekologii i położnictwie, kardiologii i kardiochirurgii, onkologii, ortopedii, pediatrii, reumatologii, stomatologii i urologii (co przedstawiono w niniejszej, drugiej części artykułu). Termografia
jest obiecującą, uzupełniającą metodą diagnostyczną. Ma zarówno zalety (bezinwazyjność, szybkość wykonania, możliwość obrazowania całego ciała i jednoczesnego wykrycia wielu problemów zdrowotnych oraz diagnozowanie na etapie subklinicznym), jak i wady (wrażliwość pomiaru na czynniki zewnętrzne, takie jak zmiany temperatury otoczenia, wilgotność i ruch powietrza), o których należy pamiętać podczas jej stosowania.
Rapid sequence intubation. The current state of knowledge
Authors: Radkowski Paweł , Kędziora Bartosz , Dawidowska-Fidrych Justyna , Podhorodecka Katarzyna , Opolska Justyna
Published: September 2024

Rapid sequence intubation is a widely practiced method for handling the airway during anaesthesia induction in patients with gastric problems or those susceptible to regurgitation or aspiration. Preparation involves gathering essential equipment and medications for emergency intubation, including oxygen, suction, bag-valve mask, laryngoscope, endotracheal tubes with stylets, resuscitation gear, and rescue tools. Despite its consistent use for over five decades, debates persist regarding the efficacy of specific elements of the method, such as cricoid pressure and the assessment of fasting in urgent surgical cases. The absence of standardised rapid sequence intubation techniques and universally accepted guidelines has resulted in discrepancies in published data. Cricoid pressure, also known as the Sellick manoeuvre, is a controversial element of rapid sequence intubation that has both supporters and critics. While it has been used for decades and is recommended by many countries to prevent pulmonary aspiration during anaesthesia, recent research has raised questions about its effectiveness. In patients undergoing emergency surgery, ultrasound of the gastric antrum may help evaluate the size of gastric contents in order to minimise the risk of aspiration pneumonia. Techniques and variants of anaesthetic induction in the rapid sequence intubation algorithm should be adapted to a wide range of clinical groups – particularly in children, obese patients and pregnant women. In paediatric anaesthesia and for obese patients, the traditional rapid sequence intubation with apnoea is not commonly used due to their limited respiratory reserve. Despite its numerous side effects, succinylcholine remains the most frequently employed drug for rapid sequence intubation.
Dyslipidemias in children
Authors: Bujanowicz Adam , Skrzypczyk Piotr
Published: September 2024

Zaburzenia lipidowe (dyslipidemie) u dzieci były do tej pory kojarzone z uwarunkowaniami genetycznymi (np. rodzinną hipercholesterolemią). W ostatnich latach, ze względu na niekorzystne zmiany trybu życia, poza wrodzonymi postaciami dyslipidemii coraz częściej stwierdza się już u dzieci nabyte, uwarunkowane środowiskowo zaburzenia lipidowe, co niesie za sobą ryzyko rozwoju miażdżycy, a w przyszłości – wystąpienia incydentów sercowo-naczyniowych. W roku 2021 ukazały się polskie rekomendacje dotyczące diagnostyki i leczenia dyslipidemii, w których po raz pierwszy tak szeroko omówiono także populację dziecięcą. W artykule przedstawiono metabolizm lipidów i normy wskaźników lipidowych w wieku rozwojowym. Ponadto opisano najczęstsze uwarunkowane genetycznie dyslipidemie, a także postacie wtórne do chorób nerek i cukrzycy. Omówiono też sposoby leczenia zaburzeń lipidowych w wieku rozwojowym. Wszystkie dzieci z dyslipidemią wymagają postępowania niefarmakologicznego. Przedstawiono wskazania do wdrożenia farmakoterapii, najczęściej stosowane leki, dawkowanie i możliwe powikłania. Szczegółowo omówiono zasady stosowania statyn u dzieci.
Diagnostic and treatment difficulties of carcinoid heart disease. Clinical case presentation
Authors: Brodowska-Kania Dorota Anna , Saracyn Marek , Kołodziej Maciej , Mróz Adrianna , Kania Michał , Dmochowska Beata , Kamiński Grzegorz
Published: September 2024

Nowotwory neuroendokrynne rozwijają się z komórek rozproszonego układu wydzielania wewnętrznego. Występują rzadko. Charakteryzują się podstępnym przebiegiem i często rozpoznawane są przypadkowo. Prezentujemy przypadek kliniczny pacjenta, który przebył nefrektomię lewostronną z powodu raka brodawkowatego nerki. Podczas operacji wykryto zmianę ogniskową w krezce, z której pobrano wycinki do badania histopatologicznego. Rozpoznano nowotwór neuroendokrynny. Zastosowano leczenie długodziałającym analogiem somatostatyny. W dalszej obserwacji podczas progresji choroby wykryto przerzut nowotworu neuroendokrynnego do mięśnia sercowego, co zdarza się niezwykle rzadko. W związku z progresją do przewlekłego leczenia długodziałającym analogiem somatostatyny dołączono radioizotopową terapię celowaną molekularnie. Uzyskano stabilizację choroby. Po upływie 1,5 roku zaobserwowano drugą progresję choroby i zastosowano kolejny raz radioizotopową terapię celowaną molekularnie, z dobrym skutkiem. W pracy opisujemy również trudności diagnostyczne spowodowane zbyt małą czułością najczęściej stosowanych metod obrazowania serca, takich jak echokardiografia czy rezonans magnetyczny, które ustępują metodom obrazowania molekularnego w zakresie wykrywania przerzutów nowotworów neuroendokrynnych. Wiedza na temat przerzutów nowotworów neuroendokrynnych do serca jest nadal niewielka. Nadal nie jest jasny ich wpływ na dalszy przebieg choroby i rokowanie pacjenta. W związku z tym niezbędne jest przeprowadzenie większej liczby badań.
The impact of tirzepatide on lipid profile based on the SURMOUNT clinical trials
Authors: Brzdęk Kinga , Brzdęk Michał
Published: September 2024

Hiperlipidemia, czyli wysokie stężenie lipidów we krwi, stanowi istotny czynnik ryzyka chorób sercowo-naczyniowych. Tirzepatyd to podwójny agonista receptorów polipeptydu insulinotropowego zależnego od glukozy oraz glukagonopodobnego peptydu-1. Według wskazań lek ten stosuje się w cukrzycy typu 2 oraz otyłości i nadwadze u dorosłych pacjentów w celu redukcji masy ciała. W ostatnich latach pojawiły się także doniesienia, że tirzepatyd korzystnie wpływa na profil lipidowy. W pracy podsumowano dane z badań klinicznych SURMOUNT, aby ocenić, jak tirzepatyd wpływa na profil lipidowy. Analiza wykazała wiele korzyści wynikających z przyjmowania tego leku. Dodatkowo korzystny profil bezpieczeństwa podnosi jego atrakcyjność jako leku stosowanego u osób z zaburzeniami lipidowymi. Tirzepatyd może być przełomowym lekiem w leczeniu nie tylko otyłości i cukrzycy typu 2, ale także dyslipidemii. Jednak pomimo obiecujących wyników, potrzebne są dalsze badania, aby zrozumieć długoterminowe bezpieczeństwo i koszty związanych ze stosowaniem tego leku. Będą one kluczowe dla opracowania indywidualnych planów terapeutycznych i optymalizacji wykorzystania tirzepatyd w różnych podgrupach pacjentów.
Tình trạng tâm lý của người bệnh trước phẫu thuật tại Trung tâm Tai Mũi Họng & AMP; phẫu thuật cấy ốc tai Bệnh viện Đại học Y Hà Nội
Authors: Quân Đỗ Quang Minh , Trung Trương Quang , Nguyên Lê Thị Thảo
Published: September 2024

Mục tiêu nghiên cứu: Nghiên cứu này được thực hiện nhằm mô tả mức độ tâm lý của người bệnh được điều trị tại Trung tâm Tai mũi họng và Phẫu thuật cấy ốc tai Bệnh viện Đại học Y Hà Nội và tìm hiểu một số yếu tố ảnh hưởng đến tâm lý của người bệnh. Phương pháp nghiên cứu: Thiết kế nghiên cứu mô tả cắt ngang được thực hiện trên 123 người bệnh bằng cách sử dụng bộ câu hỏi đánh giá lo âu State – Trait Anxiety Inventory (STAI) quý I năm 2023. Kết quả: 45% người bệnh có lo lắng về Trạng thái tâm lý, 33% người bệnh có lo lắng về Đặc điểm tâm lý. Giới tính, nơi sống và mức độ không chắc chắn về tình trạng bệnh là những yếu tố có ảnh hưởng đến tâm lý của người bệnh.
Evolution of Value Systems in the “Era of Great Changes”: General Challenges and Problems
Authors: Yakovlev A. I.
Published: September 2024

The article examines the evolution of the system of traditional values in the era of fundamental changes in the social system. Values of different levels are considered: formational, belonging to a certain social system and changing with the change of the system, as well as civilizational, deep values, generated in a certain religious and cultural space and preserved in the system of ideals and norms of behavior of many generations.

Values reflect and express a certain state of the whole society. With the change of the social system through formational evolution in the West or through “catch-up modernization” in non-Western countries, changes occur in the system of values as an interconnected set of ideals, ideas and norms. Traditional values, as a rule, retreat before the values of “today”, generated by society itself or borrowed from outside. Conflicts of identity and self-identity of the individual and society arise.

In the first decades of the 21st century, in the context of the beginning of the change of the world order, new meanings of development are being developed and sought. The processes of globalization (technological revolution, global migration, flows of goods and information), as well as the West’s desire to maintain the dominant order, while nonWestern countries strengthen their importance in the world system, give rise to conflicts of values at different levels. However, not every civilizational challenge becomes a threat to traditional values. In non-Western societies, there is an adaptation of their value system to changed conditions while maintaining fidelity to the ideals and norms of their cultural and religious tradition.
Transformation of Post-Soviet Russia’s Interests in the Asia-Pacific Region
Authors: Konovalov I. A.
Published: September 2024

The relevance of this study is due to the significant transformation of the system of international relations caused by the geopolitical transit from the Atlantic to the Pacific Ocean. In the context of modern global changes and dynamic processes in the international arena, the study of the transformation of Russia’s interests in the Asia-Pacific region (APR) is becoming especially important. It provides an opportunity to predict future trends in international relations and develop specific recommendations for the development of Russia’s foreign policy strategy. In the context of worsening relations with the West and Russia’s turn to the East, this study allows us to better understand key trends in the region and develop strategic solutions to strengthen Russia’s geopolitical status in the Asia-Pacific region. In particular, it is important to take into account the economic, political and military aspects of Russia’s presence in this dynamically developing region. Thus, this study plays a key role in shaping Russia’s long-term foreign policy strategy and its adaptation to new geopolitical realities, not only in order to strengthen its position in the Asia-Pacific region, but also to respond more effectively to the challenges and opportunities arising from the transformation of the global system of international relations.
Molecular toxicological prediction of the ethanolic extract of the species Siparuna guianensis
Authors: Rodrigues Elizângela Sofia Ribeiro , Moreira Rodrigo De Faveri , Ramos Ryan da Silva , Oliveira Micael Davi Lima de , Silva Nadine Guimarães da , Lima Emerson Silva , Aguiar Raimundo Wagner de Souza
Published: September 2024

The species Siparuna guianensis has anti-inflammatory, analgesic and anti-infectious potential, but there is a lack of safety and toxicity parameters for the medicinal use of the plant. The aim of this study was to identify the phytochemical compounds and carry out the molecular toxicological prediction of the ethanolic extract of the species Siparuna guianensis. The ethanolic extract of the leaves of S. guianensis was obtained and GC-MS gas chromatography was carried out to identify the secondary metabolites, for subsequent quantification of the in silico toxicological properties in terms of carcinogenicity in rodents, Ames mutagenicity, eye irritation, skin irritation and sensitization. The molecules 2-undecanone, decanoic acid, ethyl ester of decanoic acid and 2-tetradecanone were the most satisfactory, with no risk of carcinogenicity in female mice, mutagenicity, skin sensitization or eye irritation, which suggests that the plant could be a promising and safe source for the development of future drugs with low toxicological potential.
Review of the literature of riverside education in the Amazon
Authors: Alves Dilcélia Rodrigues , Silva José Bittencourt da , Hage Salomao Antonio Mufarrej
Published: September 2024

The study is the result of Master's research, carried out with the Postgraduate Program in Curriculum and Management of Basic Schools (PPEB), of the Center for Transdisciplinary Studies in Basic Education (NEB) of the Federal University of Pará (UFPA) and aims to The objective is to carry out a literature review analysis on the theoretical production of riverside education. For the development of academic research, a qualitative approach was chosen, through bibliographic research to analyze scientific documents. The results indicate that education developed in the riverside territory is centered on the “urbanocentric” model, centered on the interests of capital. To counter this conception of teaching, entities and social groups have defended an education that respects the diversity of the field, encouraging the formulation of pedagogical projects that focus on recognizing the voices, stories and struggles of Amazonian populations.
SUPERFICIAL MYCOSES
Authors: А.А. AMANGELDI , A.K. SADANOV , B.B. BAIMAKHANOVA , L.P. TRENOZHNIKOVA , A.S. BALGIMBAEVA , O.N. LAKHK , S.E. ORAZYMBET , I.R. KULMAGAMBETOV , Sh. M. MIRALIMOVA
Published: September 2024

This review examines the problem of the spread of surface mycoses and their pathogens. Dermatophytes are filamentous fungi that cause dermatophytosis in humans and animals. Special attention is paid to the current epidemiological trends of fungal infections and dermatomycoses of the skin are considered. The main types of fungal skin diseases and factors affecting the virulence of fungi are described.

В данном обзоре рассматривается проблемараспространения поверхностных микозов и его возбудителей. Дерматофиты — это нитчатые грибы, вызывающие дерматофитозы у людей и животных. Рассмотрены дерматомикозы кожи, особое внимание уделено современным эпидемиологическим тенденциям грибковых инфекций.Описаны основные виды грибковых заболеваний кожии факторы, влияющие на вирулентность грибов.
ANTIFUNGAL ACTIVITY, MECHANISM OF ACTION AND PHARMOKINETICS OF AZOLES
Authors: А.К. SADANOV , А.S. BALGIMBAYEVA , N.S. ONGARBAYEVA , V.E. BEREZIN , B.B. BAIMAKHANOVA , O.N. LAKHK , I.R. KULMAGAMBETOV , L.N. IBRAGIMOVA , G.B. BAIMAKHANOVA , T.D. DOOLOTKELDIEVA , L.P. TRENOZHNIKOVA
Published: September 2024

Abstract The review article provides information on the chemical nature, spectrum and mechanism of action, pharmokinetics of azoles, representing a class of effective synthetic antifungal compounds used in the treatment of superficial and deep human mycoses.

В обзорной статье приводятся сведения о химической природе, спектре и механизме действия, фармокинетике азолов, представляющих класс эффективных синтетических противогрибковых соединений, применяемых при лечении поверхностных и глубоких микозов человека.
Handling severe asthma exacerbations: Current guidelines and techniques
Authors: AL Khathami Mohammed Mesfer Musaed , Alsaeed Abdulaziz Abdullah , Alareefi Hind Saad , Alharbi Sanad Samah , Al Jasser Saleh Abdullatif , Alanazi Amani Ayyadhah , Alsulami Abdulkarim Hamed , Daghas Ibrahim Ahmad , Alghamdi Najlaa Saeed
Published: September 2024

Background: Asthma affects approximately 300 million people globally, with a significant prevalence of uncontrolled cases contributing to rising hospitalizations and healthcare costs. In Saudi Arabia, 64% of asthma patients experience uncontrolled symptoms. Effective management of severe asthma exacerbations is critical, yet many patients remain inadequately controlled even in advanced care settings. Aim: This review aims to synthesize current guidelines and techniques for handling and management of severe asthma exacerbations, focusing on optimizing therapeutic strategies and improving patient outcomes via pharmacists and Emergency medical services. Methods: The review systematically examines existing guidelines, including the Saudi Initiative for Asthma (SINA) and other international protocols. It evaluates various treatments such as inhaled bronchodilators, systemic steroids, anticholinergic agents, and newer therapies like magnesium sulfate and heliox. The review also considers the effectiveness of different diagnostic and monitoring tools. Results: Effective management of severe asthma exacerbations involves a multi-faceted approach. Key strategies include the use of inhaled bronchodilators (MDIs preferred over nebulizers), systemic steroids for moderate to severe cases, and oxygen therapy to address hypoxemia. Anticholinergic agents and magnesium sulfate may be used for severe exacerbations, though their benefits vary.
Study on the preparation of bimetallic silver-copper nanoparticles by electron beam irradiation
Authors: Nguyen Ngoc Duy , Nguyen Thi Kim Lan , Dang Van Phu , Nguyen Chi Thuan , Le Anh Quoc , Cao Van Chung , Phan Phuoc Thang
Published: September 2024

Silver and copper nanoparticles are well-known as good antimicrobial agents. In this study, we reported the preparation and characterization of bimetallic silver-copper nanoparticles (Ag-CuNPs) prepared by the electron beam (EB) irradiation method. Chitosan (CTS) was used as a stabilizer agent. The obtained Ag-CuNPs were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), and UV-Vis spectrophotometry. The influence of the different concentrations in the range of 100–1,000 ppm of Ag+ and Cu2+ ions at the mass ratio of [Ag+]:[Cu2+] = 1/1 on the particle size and particle size distribution of the Ag-CuNPs was investigated. The TEM results showed that the average size of the Ag-CuNPs was 11.02–13.73 nm when the total concentration of Ag+ and Cu2+ ions was 250 – 1,000 ppm, respectively. The EB-irradiation method can be applied in the production of Ag-CuNPs on a large scale.
Localizing Bilateral Finance for Community Rights: Recommendations for United States Agency for International Development
Authors:   The Path to Scale
Published: September 2024

Through informal conversations in 2023, the United States Agency for International Development (USAID) leadership expressed interest in working with the Path to Scale to identify best practices for funding local rightsholder organizations in keeping with the Forest Tenure Pledge and its localization agenda. This report aims to influence the localization agenda and improve bilateral policies and practices to ensure that more direct, fit-for-purpose support reaches Indigenous Peoples, local communities, and Afro-descendant Peoples and their supporting organizations to secure tenure rights and conserve key ecosystems and biodiversity.
Causas del diseño industrial en Colombia
Authors: Álvarez-Romero Fernando Alberto
Published: September 2024

Afortunadamente, sobre el diseño no se tiene una sola historia, sino que, por el contrario, devienen variadas historias que desencadenan infinidad de interpretaciones y prácticas, en la medida en que transcurre el tiempo y nuevas generaciones las reescriben. Esta es una de esas historias que parte del trabajo originado al interior del doctorado de Diseño y Creación de la Universidad de Caldas, dentro de un capítulo de la tesis: Rearticulaciones. Dicho proyecto fue cofinanciado por la Universidad Jorge Tadeo Lozano en la modalidad de un proyecto de investigación (Álvarez, 2022).
Del diseño a la cerámica
Authors: Cadavid-Blanco Zoraida
Published: September 2024

La narrativa inicia en 1974 cuando la autora ingresa al Instituto Técnico Artístico (ITAE) en Bucaramanga, Colombia. Bajo la influencia de su profesor, David Consuegra, descubre el diseño y las vanguardias artísticas. A lo largo del texto, se relata su incursión en la editorial familiar y la creación de Triblos, un proyecto que fracasó por falta de experiencia administrativa. Posteriormente, se trasladan a Bogotá, donde investigan sobre ornamentación y tipografía vernácula, culminando en importantes publicaciones y exhibiciones. La obra refleja una vida dedicada al diseño, la docencia y la investigación.
Relatos
Authors: Agudelo-Bernal Carolina , Hernández-Olave Juan Sebastián
Published: September 2024

En la historia del diseño en Colombia, es común encontrar la falta de reconocimiento de iniciativas y proyectos colectivos en el ámbito académico y profesional. Estas visiones incompletas dificultan la identificación de logros y errores en el desarrollo del diseño. Este capítulo busca reconstruir la memoria histórica de la asociatividad en el diseño durante la segunda mitad del siglo XX. Mediante entrevistas a académicos y profesionales, y la revisión de material documental, se registran las distintas formas de asociatividad, con el objetivo de abrir nuevas posibilidades y discusiones en torno a la construcción de comunidades profesionales.
Otra historia del diseño gráfico en Colombia
Authors: Páez-Vanegas Leonardo
Published: September 2024

La investigación explora el desarrollo de libros de texto escolares en Colombia durante la Tercera Misión Pedagógica Alemana (décadas de 1960 y 1970). Durante esta misión, expertos alemanes asesoraron al gobierno colombiano en reformas educativas, incluyendo la creación de material didáctico. Se documentó la producción editorial de la época, destacando la relevancia del diseño gráfico y los medios editoriales locales. Esto permitió visibilizar la contribución de artistas gráficos desconocidos en la elaboración de dichos textos.
¿Qué tienen de común un rinoceronte, un pavo real y un camello bajo un baobab?
Authors: López-Osorno Jaime
Published: September 2024

A lo largo de los años, he notado cómo el tiempo se acelera, impulsándonos a ordenar recuerdos y revisar decisiones que han marcado nuestra trayectoria. Trabajar en el ámbito académico por mucho tiempo a menudo hace que nuestro destino personal se entrelace con el de las instituciones. Este testimonio explora la creación del Programa de Pregrado de Diseño de la Universidad Autónoma de Occidente de Cali, iniciado en 1999. Refleja cómo, a través de desafíos y logros, se consolidó como una instancia formadora para diseñadores, obteniendo reconocimiento oficial y estableciendo raíces profundas en el campo del diseño.