bluuebunny/crossref_metadata_2025 huggingface dataset:
Modelling the disappearance of coarse woody debris, following a land clearing event
Authors: Pringle Matthew J. , Bray Steven G. , Carter John O.
Published: December 2021

Background

Land clearing generates coarse woody debris (CWD), much of which ultimately becomes atmospheric CO2. Schemes for greenhouse gas accounting must consider the contribution from land clearing, but the timing of the contribution will have large uncertainty, due to a paucity of knowledge about the rate of CWD disappearance. To better understand above-ground CWD disappearance following a land clearing event—through the actions of microorganisms, invertebrates, wildfire, or deliberate burning—we combined statistical modelling with an archive of semi-quantitative observations (units of CWD %), made within Queensland, Australia.

Results

Using a generalised additive mixed-effects model (median absolute error = 14.7%), we found that CWD disappearance was strongly influenced by the: (i) number of years elapsed since clearing; (ii) clearing method; (iii) bioregion (effectively a climate-by-tree species interaction); and (iv) the number of times burned. Years-since-clearing had a strongly non-linear effect on the rate of CWD disappearance. The data suggested that disappearance was reverse-sigmoidal, with little change in CWD apparent for the first three years after clearing. In typical conditions for Queensland, the model predicted that it will take 38 years for 95% of CWD to disappear, following a land clearing event; however, accounting for uncertainty in the data and model, this value could be as few as 5 years, or > 100 years. In contrast, due to an assumption about the propensity of land managers to burn CWD, the official method used to assess Australia’s greenhouse gas emissions predicted that 95% of CWD will disappear in < 1 year.

Conclusions

In Queensland, the CWD generated by land clearing typically takes 38 years to disappear. This ultimately implies that a key assumption of Australia’s official greenhouse gas reporting—i.e. that 98% of CWD is burned soon after a clearing event—does not adequately account for delayed CO2 emissions.
Basal lamina changes in neurodegenerative disorders
Authors: Nguyen Benjamin , Bix Gregory , Yao Yao
Published: December 2021

Background

Neurodegenerative disorders are a group of age-associated diseases characterized by progressive degeneration of the structure and function of the CNS. Two key pathological features of these disorders are blood-brain barrier (BBB) breakdown and protein aggregation.

Main body

The BBB is composed of various cell types and a non-cellular component---the basal lamina (BL). Although how different cells affect the BBB is well studied, the roles of the BL in BBB maintenance and function remain largely unknown. In addition, located in the perivascular space, the BL is also speculated to regulate protein clearance via the meningeal lymphatic/glymphatic system. Recent studies from our laboratory and others have shown that the BL actively regulates BBB integrity and meningeal lymphatic/glymphatic function in both physiological and pathological conditions, suggesting that it may play an important role in the pathogenesis and/or progression of neurodegenerative disorders. In this review, we focus on changes of the BL and its major components during aging and in neurodegenerative disorders, including Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS). First, we introduce the vascular and lymphatic systems in the CNS. Next, we discuss the BL and its major components under homeostatic conditions, and summarize their changes during aging and in AD, PD, and ALS in both rodents and humans. The functional significance of these alterations and potential therapeutic targets are also reviewed. Finally, key challenges in the field and future directions are discussed.

Conclusions

Understanding BL changes and the functional significance of these changes in neurodegenerative disorders will fill the gap of knowledge in the field. Our goal is to provide a clear and concise review of the complex relationship between the BL and neurodegenerative disorders to stimulate new hypotheses and further research in this field.
WDR26 and MTF2 are therapeutic targets in multiple myeloma
Authors: Sun Fumou , Cheng Yan , Riordan Jesse D. , Dupuy Adam , Dubois Wendy , Pisano Michael , Dong Jing , Mock Beverly , Zhan Fenghuang , Hari Parameswaran , Janz Siegfried
Published: December 2021

Unbiased genetic forward screening using retroviral insertional mutagenesis in a genetically engineered mouse model of human multiple myeloma may further our understanding of the genetic pathways that govern neoplastic plasma cell development. To evaluate this hypothesis, we performed a tumor induction study in MYC-transgenic mice infected as neonates with the Moloney-derived murine leukemia virus, MOL4070LTR. Next-generation DNA sequencing of proviral genomic integration sites yielded rank-ordered candidate tumor progression genes that accelerated plasma cell neoplasia in mice. Rigorous clinical and biological validation of these genes led to the discovery of two novel myeloma genes: WDR26 (WD repeat-containing protein 26) and MTF2 (metal response element binding transcription factor 2). WDR26, a core component of the carboxy-terminal to LisH (CTLH) complex, is overexpressed or mutated in solid cancers. MTF2, an ancillary subunit of the polycomb repressive complex 2 (PRC2), is a close functional relative of PHD finger protein 19 (PHF19) which is currently emerging as an important driver of myeloma. These findings underline the utility of genetic forward screens in mice for uncovering novel blood cancer genes and suggest that WDR26-CTLH and MTF2-PRC2 are promising molecular targets for new approaches to myeloma treatment and prevention.
Enterobacter hormaechei in the intestines of housefly larvae promotes host growth by inhibiting harmful intestinal bacteria
Authors: Zhang Qian , Wang Shumin , Zhang Xinyu , Zhang Kexin , Liu Wenjuan , Zhang Ruiling , Zhang Zhong
Published: December 2021

Background

As a pervasive insect that transmits a variety of pathogens to humans and animals, the housefly has abundant and diverse microbial communities in its intestines. These gut microbes play an important role in the biology of insects and form a symbiotic relationship with the host insect. Alterations in the structure of the gut microbial community would affect larval development. Therefore, it is important to understand the mechanism regulating the influence of specific bacteria on the development of housefly larvae.

Methods

For this study we selected the intestinal symbiotic bacterium Enterobacter hormaechei, which is beneficial to the growth and development of housefly larvae, and used it as a probiotic supplement in larval feed. 16S rRNA gene sequencing technology was used to explore the effect of E. hormaechei on the intestinal flora of housefly larvae, and plate confrontation experiments were performed to study the interaction between E. hormaechei and intestinal microorganisms.

Results

The composition of the gut microflora of the larvae changed after the larvae were fed E. hormaechei, with the abundance of Pseudochrobactrum, Enterobacter and Vagococcus increasing and that of Klebsiella and Bacillus decreasing. Analysis of the structure and interaction of larval intestinal flora revealed that E. hormaechei inhibited the growth of harmful bacteria, such as Pseudomonas aeruginosa, Providencia stuartii and Providencia vermicola, and promoted the reproduction of beneficial bacteria.

Conclusions

Our study has explored the influence of specific beneficial bacteria on the intestinal flora of houseflies. The results of this study reveal the important role played by specific beneficial bacteria on the development of housefly larvae and provide insight for the development of sustained biological agents for housefly control through interference of gut microbiota.

Graphical abstract
RT-QuIC detection of pathological prion protein in subclinical goats following experimental oral transmission of L-type BSE
Authors: Favole Alessandra , Mazza Maria , D’Angelo Antonio , Lombardi Guerino , Palmitessa Claudia , Dell’Atti Luana , Cagnotti Giulia , Berrone Elena , Gallo Marina , Avanzato Tiziana , Messana Erika , Masoero Loretta , Acutis Pier Luigi , Meloni Daniela , Cardone Franco , Caramelli Maria , Casalone Cristina , Corona Cristiano
Published: December 2021

Objective

The spread of bovine spongiform encephalopathy (BSE) agent to small ruminants is still a major issue in the surveillance of transmissible spongiform encephalopathies (TSEs). L-type bovine spongiform encephalopathy (L-BSE) is an atypical form of BSE with an unknown zoonotic potential that is transmissible to cattle and small ruminants. Our current knowledge of bovine atypical prion strains in sheep and goat relies only on experimental transmission studies by intracranial inoculation. To assess oral susceptibility of goats to L-BSE, we orally inoculated five goats with cattle L-BSE brain homogenates and investigated pathogenic prion protein (PrPsc) distribution by an ultrasensitive in vitro conversion assay known as Real-Time Quaking Induced Conversion (RT-QuIC).

Results

Despite a prolonged observation period of 80 months, all these animals and the uninfected controls did not develop clinical signs referable to TSEs and tested negative by standard diagnostics. Otherwise, RT-QuIC analysis showed seeding activity in five out of five examined brain samples. PrPsc accumulation was also detected in spinal cord and lymphoreticular system. These results indicate that caprine species are susceptible to L-BSE by oral transmission and that ultrasensitive prion tests deserve consideration to improve the potential of current surveillance systems against otherwise undetectable forms of animal prion infections.
Methotrexate-induced toxidermia and pancytopenia in a patient with ectopic pregnancy: a case report
Authors: Refeno Valéry , Rasamimanana Naharisoa Giannie , Abasse Baco Abdallah , Ramarokoto Malalafinaritra Patrick Marco , Fanomezantsoa Mahefaniaina Jean Eustache , Randaoharison Pierana Gabriel
Published: December 2021

Background

Methotrexate is an anticancer drug from the antimetabolite class. It is also used in gynecology and obstetrics and is the molecule of choice for the medical treatment of ectopic pregnancies. We report a case of toxidermia associated with severe pancytopenia induced by methotrexate for ectopic pregnancy.

Case presentation

A 30-year-old Malagasy (African) woman was admitted to the Emergency and Intensive Care Department for probable toxidermia following injection of 75 mg of methotrexate for an ectopic pregnancy. She had developed generalized erythema, which started 48 hours after the injection. The secondary onset of phlyctenular maculopapular skin lesions, generalized purpura, and erosions of the oral mucosa in a context of febrile jaundice prompted her hospitalization. On admission, the patient presented with febrile neutropenia, pancytopenia, renal failure, and hepatic cytolysis. She received transfusions of fresh whole blood, erythromycin, and amphotericin B. The course was fatal within 2 days of hospitalization. The patient died of multiple organ failure.

Conclusions

Our case is mainly distinguished by the lack of use of granulocyte growth factors and folinic acid. In the event of severe reactions to methotrexate, the management should be multidisciplinary and as much as possible within an intensive care unit.
Role of barium enema examination for the diagnosis of submucosal invasion depth in T1 colorectal cancers
Authors: Kawasaki Keisuke , Torisu Takehiro , Nagahata Takahisa , Esaki Motohiro , Kurahara Koichi , Eizuka Makoto , Tanaka Yoshihito , Fujiwara Minako , Kawatoko Shinichiro , Oshiro Yumi , Yamada Shun , Ikegami Koji , Fujioka Shin , Fuyuno Yuta , Matsuno Yuichi , Umeno Junji , Moriyama Tomohiko , Kitazono Takanari , Sugai Tamotsu , Matsumoto Takayuki
Published: December 2021

Background

The indication for endoscopic resection for submucosally invasive colorectal cancer (T1-CRC) depends on the preoperative diagnosis of invasion depth. The aim of this investigation was to evaluate the association between barium enema examination (BE) profile views and depth of submucosal (SM) invasion in CRCs.

Methods

We reviewed the radiographic and endoscopic findings of 145 T1-CRCs diagnosed from 2008 to 2019. We measured the widths of horizontal and vertical rigidity under a BE profile view corresponding to CRC and compared the values with SM invasion depth. Horizontal rigidity was defined as the horizontal length and vertical rigidity as the vertical width of the barium defect corresponding to each target lesion. The most appropriate cut-off values for predicting SM invasion ≥1.8 mm were calculated by receiver operating characteristic curve analysis.

Results

Values of horizontal rigidity (r = 0.626, P < 0.05) and vertical rigidity (r = 0.482, P < 0.05) correlated significantly with SM invasion depth. The most appropriate cut-off values for the prediction of SM invasion depth ≥ 1.8 mm were 4.5 mm for horizontal rigidity, with an accuracy of 80.7%; and 0.7 mm for vertical rigidity, with an accuracy of 77.9%. The prevalence of lympho-vascular invasion was significantly different when those cut-off values were applied (43.2% vs. 17.5% for horizontal rigidity, P < 0.005).

Conclusions

In T1-CRC, values of horizontal and vertical rigidities under a BE profile view were correlated with SM invasion depth. While the accuracy of the rigidities for the prediction of SM invasion depth ≥ 1.8 mm was not high, horizontal rigidity may be predictive of lympho-vascular invasion, thus aiding in therapeutic decision-making.
Increasing power in the analysis of responder endpoints in rheumatology: a software tutorial
Authors: McMenamin Martina , Grayling Michael J. , Berglind Anna , Wason James M. S.
Published: December 2021

Background

Composite responder endpoints feature frequently in rheumatology due to the multifaceted nature of many of these conditions. Current analysis methods used to analyse these endpoints discard much of the data used to classify patients as responders and are therefore highly inefficient, resulting in low power. We highlight a novel augmented methodology that uses more of the information available to improve the precision of reported treatment effects. Since these methods are more challenging to implement, we developed free, user-friendly software available in a web-based interface and as R packages. The software consists of two programs: one that supports the analysis of responder endpoints; the second that facilitates sample size estimation. We demonstrate the use of the software to conduct the analysis with both the augmented and standard analysis method using the MUSE study, a phase IIb trial in patients with systemic lupus erythematosus.

Results

The software outputs similar point estimates with smaller confidence intervals for the odds ratio, risk ratio and risk difference estimators using the augmented approach. The sample size required in each arm for a future trial using the novel approach based on the MUSE data is 50 versus 135 for the standard method, translating to a reduction in required sample size of approximately 63%.

Conclusions

We encourage trialists to use the software demonstrated to implement the augmented methodology in future studies to improve efficiency.
Cardiac magnetic resonance imaging in patients with Behçet's disease
Authors: Ahmed Ali A. , Tharwat Samar , Batouty Nihal M. , El Bahy Ahmed , Tawfik Ahmed M. , Shahin Dina A.
Published: December 2021

Background

Behçet’s disease (BD) is a multisystemic vasculitis that may affect the heart. However, the incidence and nature of cardiac involvement in BD have not been clearly documented yet. The aim of this study was to delineate the cardiac magnetic resonance imaging (MRI) appearances of cardiac involvement in BD patients.

Methods

This cross-sectional observational study was carried out 30 BD patients without known cardiac disease. Patients were subjected to history taking, physical examination, echocardiography and cardiac MRI.

Results

At least one abnormality on cardiac MRI was observed in 20/30 patients (66.67%). Myocardial oedema was observed in 3 patients (10%) and late gadolinium enhancement in 1 patient (3.3%). Pericardial effusion was found in 3 patients (10.0%), global hypokinesia in 6 patients (20.0%) and intra-cardiac thrombosis in only 1 patient (3.3%). Pulmonary artery was dilated in 4 patients (13.3%). Left ventricular (LV) and right ventricular (RV) end diastolic volume were altered in 4 patients (13.3%) and 7 patients (23.3%) respectively. LV and RV end systolic volume were abnormal in 7 patients (23.3%) and 5 patients (16.7%) respectively. There was aortic valve regurge in 2 patients (6.7%), tricuspid valve regurge in 9 patients (30%), and mitral valve regurge in 9 patients (30%). Dilated left main coronary artery was found in 2 patients (6.7%) and arrhythmogenic right ventricular dysplasia in only one patient 1 patient (3.3%). On logistic regression analysis, BD activity index score was a significant predictor of cardiac abnormalities.

Conclusion

BD may cause cardiac abnormalities without clinical manifestations and cardiac MRI may represent a tool for early detection of these subtle abnormalities. Higher BD activity index scores are strongly linked to cardiac problems.
The psychological impact of inflammatory bowel disease as regards anxiety and depression: a single-center study
Authors: Askar Safaa , Sakr Mohamed Amin , Alaty Waleed Hamed Abd , Aufa Ola M. , Kamel Shimaa Y. , Eltabbakh Mohamed , Sherief Ahmed F. , Shamkh Mostafa A. A. , Rashad Heba
Published: December 2021

Background

Patients suffering from inflammatory bowel disease (IBD) are not systematically screened against depression as well as anxiety, although there are high prevalence and adverse influence on the quality of life. The aim of this work was to determine generalized anxiety disorder and major depressive disorder prevalence in patients with IBD, and the secondary objective was to identify patient properties linked to higher psychiatric disorder rates.

Results

We determined anxiety and depression prevalence in 105 IBD patients (82 having ulcerative colitis and 23 suffering from Crohn’s disease) through a psychiatric interview using the Arabic version of Structured Clinical Interview for DSM IV Axis I diagnosis (SCID I), in addition to severity assessment of major depressive disorder and generalized anxiety disorder using the Hamilton Depression Scale (HAM-D) and the Hamilton Anxiety Scale (HAM-A), respectively. Patient data, disease characteristics, and drug information were also gathered. We found a high depression prevalence of 56.2% (n = 59), followed by 37.1% (n = 39), with no significant association between IBD severity and anxiety and depression severity.

Conclusion

Depression and/or anxiety affected a large number of IBD patients. Such psychiatric disorders’ frequency would warrant detection as well as referral to psychiatric treatment.
Multidisciplinary approach of teaching radiology to medical students in Egypt: Is this an effective method?
Authors: Nabhani Yasmeen , Xie Victoria K. , Badawy Mohamed , Karim Rehan , Abdullatif Umayma , Negm Ahmed S. , Bhosale Hrishabh , Rohren Scott , Elhatw Ahmed , Ghannam Sammar , Abusaif Abdelrahman , Elsamaloty Mazzin , Shalaby Nada , Choucair Ferial , Khalifa Islam , Saad Mariam Ahmed , Patel Parth , Almubaid Zaid , Shehata Mostafa Ahmed , ElHefnawi Yara , Kamal Serageldin , Hammad Mahmoud F. , Elsayes Khaled M.
Published: December 2021

Background

In multidisciplinary education, different perspectives from more than one discipline are used to illustrate a certain topic. The aim of this study was to evaluate the effectiveness of an online, multidisciplinary radiology curriculum to teach radiology to medical students in Egypt. A multidisciplinary team of radiologists, surgeons, and internists taught a series of 5 case-based radiology sessions on a web conference platform. Topics included common clinical case scenarios for various body systems. Undergraduate medical students across Egypt were enrolled in the course. A pre-test–post-test design was used to evaluate the efficacy of each session. Upon course completion, students filled out a subjective survey to assess the radiology education series.

Results

On average, 1000 students attended each session. For each session, an average of 734 students completed both the pre-test and post-test. There was a statistically significant increase in post-test scores compared to pre-test scores across all 5 sessions (p < 0.001) with an overall average score improvement of 63%. A subjective survey at the end of the course was completed by 1027 students. Over 96% of students found the lecture series to be a worthwhile experience that increased their imaging knowledge and interest in radiology, and that the use of a multidisciplinary approach added educational value. About 66% of students also reported that the session topics were “excellent and clinically important.” There was a marked increase in reported confidence levels in radiology competencies before and after attendance of the sessions.

Conclusions

An online radiology curriculum with a multidisciplinary approach can be implemented successfully to reach a large group of medical students and meet their educational objectives.
Del Nido versus warm blood cardioplegia in adult patients with a low ejection fraction
Authors: Arafat Amr A. , Hassan Essam , Alfonso Juan J. , Alanazi Ebtesam , Alshammari Ahmad S. , Mahmood Asif , Al-Otaibi Khaled , Adam Adam I. , Algarni Khaled D. , Pragliola Claudio
Published: December 2021

Background

Del Nido cardioplegia was recently introduced to adult cardiac surgery with encouraging results. The effect of Del Nido cardioplegia in patients with low ejection fraction (EF) has not been thoroughly evaluated. The objective of this study was to assess the safety of Del Nido cardioplegia in adult patients with low EF compared to intermittent warm blood cardioplegia.

Results

During 2018 and 2019, 73 adult patients with an EF of ≤ 40% underwent cardiac surgery using Del Nido cardioplegia. The patients were compared to a historical cohort of consecutive patients with low EF who had intermitted warm blood cardioplegia (n= 81). Patients who had Del Nido cardioplegia had significantly lower EuroSCORE II (2.73 (1.7–4.1) vs. 4.5 (2.4–7.4),P= 0.004). There were no differences in creatinine clearance and preoperative echocardiographic data between the groups. Cardiopulmonary bypass and cross-clamp times were non-significantly lower with Del Nido cardioplegia. There were no differences in stroke and postoperative echocardiographic data between the groups. No hospital mortality was reported in both groups. Peak troponin levels were significantly higher in patients who had Del Nido cardioplegia (0.88 (0.58–1.47) vs. 0.7 (0.44–1.01) ng/dL;P= 0.01); however, after multivariable regression analysis, cardiopulmonary bypass time was the only predictor of postoperative troponin level (coefficient 0.005 (95% CI: 0.003–0.008);P< 0.001). ICU stay was significantly longer in patients who had Del Nido cardioplegia (4 (3–6) vs. 2(1–4) days,P< 0.001), while postoperative hospital stay did not differ between the groups. After multivariable regression, the use of intermittent warm blood cardioplegia was significantly associated with shorter ICU stay (coefficient − 1.80 (95% CI − 3.06 – -0.55);P= 0.01).

Conclusions

Prolonged ICU was reported with Del Nido cardioplegia; however, there were no differences in the duration of hospital stay and the clinical outcomes between the groups. Despite the proven efficacy of intermittent warm blood cardioplegia, the use of Del Nido cardioplegia might be safe in patients with low EF.
A dangerous triangularization of conflicting values in academic publishing: ORCID, fake authors, and risks with the lack of criminalization of the creators of fake elements
Authors: Teixeira da Silva Jaime Α.
Published: December 2021

The mainstream publishing establishment is under attack from multiple known and unknown forces. This is neither hyperbole nor fantasy. Many academics may believe that the main threat lies with “predatory” journals or publishers, but this is not necessarily the case because such entities are not always easy to distinguish clearly from veritable scholarly journals or publishers. Moreover, there is a gray zone that may involve both predatory and exploitative qualities. Current submission systems are not fail-safe because they allow unscholarly or fraudulent elements to register and abuse them, for example for submitting fake research or falsified peer reports, while author identification tools like ORCID are imperfect and provide a platform for similar-minded individuals to “validate” themselves. This toxic mix of tools aimed at fortifying integrity, while allowing fake authors to breed, currently without many, or any, ethical or legal repercussions will rapidly erode the entire publishing landscape if serious legal action is not taken. The creation of fake papers by fake authors will eventually trickle down into valid literature, by virtue of the fact that cited literature cannot be thoroughly vetted, even in peer review. The integrity of valid scholarly venues is thus at high risk unless suitable, strict and ethically and legally enforceable preventative measures are implemented.
The deconstruction of Byzantine mode-organization and the new Chrysanthine ‘order’
Authors: Plemmenos John
Published: December 2021

This paper was written to commemorate the 200th anniversary of the publication of musical treatise by Archbishop Chrysanthos of Madytos (c.1770-1846), the first work towards a ‘scientific’ treatment of Greek ecclesiastical music (1821)[1]. Chrysanthos attempted to reorganize the modal and rhythmic theory of this music, and reform the musical notation that has remained to this day. The paper deals with an aspect of Chrysanthine modal system that has not received due attention so far: the abandonment of the traditional authentic-plagal order and its substitution by a new one that does not make sense if placed outside its cultural context and historical antecedents. Chrysanthos’ main point of reference seems to be the Ottoman makam system that had already penetrated post-Byzantine chant but was now given a new momentum[2]. Before that, Greek composers used the Byzantine modal division into four authentic (kurioi) and four plagal (plagioi), positioned a fifth apart from each other. The authentic modes were mostly ascending in terms of melodic movement, whereas the plagal were descending (though one has first to ascend in order to get down!). Otherwise, every authentic-plagal pair shared the same melodic scale (usually an octave), which they traversed according to certain melodic motifs (some common to all, others unique to every mode).[1] Chrysanthos, Εισαγωγή εις το θεωρητικόν και πρακτικόν της Εκκλησιαστικής Μουσικής / συνταχθείσα προς χρήσιν των σπουδαζόντων αυτήν κατά την νέαν μέθοδον παρά Χρυσάνθου του εκ Μαδύτων, Διδασκάλου του Θεωρητικού της Μουσικής (Paris: Rigny, 1821).[2] In this paper, the Turkish terms have been rendered into their original script except for makam (mode) and usul (rhythm), the Anglicized plural form of which (makams and usuls) has been preferred instead of the longer makamler and usuler. The Greek names have been transliterated into Latin according to British Standard for transliteration of Cyrillic and Greek characters (BS), 1958.
Chrysanthine theoretical thought and notation system-The relation between Orality and Textuality
Authors: Andrikos Nikos
Published: December 2021

Two centuries after the release of Chrysanthos’ Εισαγωγή εις το Θεωρητικόν και Πρακτικόν της Εκκλησιαστικής Μουσικής, this treatise remains one of the most important sources of theoretical thought in the field of Greek Orthodox Ecclesiastical Music. Moreover, it is widely known that the theoretical essays of Chrysanthos played a catalytic role regarding the structure of the modal system of Octaechia, the formulation of the new Parasemantiki notation, as well as contemporary performance practices. Indeed, Chrysanthos’ contribution to the reformation of the notation system as well as the way he attributed the theoretical content of Ecclesiastical Music, influenced the entire theoretical thought that was produced, at least until the last decades of the 19th century[1]. Therefore, despite individual disagreements that were expressed within the psaltic milieu of the 19th century[2], almost all of the theoreticians who succeeded Chrysanthos based their thought on his fundamental principles. Thus, it is worth mentioning that in treatises that followed the Reform of 1814, repetitions are frequently detected, even of Chrysanthos’ points that could be considered as scientifically problematic[3].[1] See Νίκος Ανδρίκος, Η Εκκλησιαστική μουσική της Σμύρνης (1800-1922), (2015), 124.[2] About this issue, see Αντώνιος Χατζόπουλος, Η εκκλησιαστική μουσική παιδεία στην εκκλησία της Κωνσταντινουπόλεως κατά το 19ο και 20ό αιώνα, (2000); Αχιλλεύς Χαλδαιάκης, “Η διδασκαλία της Ψαλτικής Τέχνης: Παρελθόν, παρόν και μέλλον”, Βυζαντινομουσικολογικά, Τόμος Α΄, Θεωρία, (2014), 50-52.[3] Among others, the most indicative example was the repetition of Chrysanthos’ misguided calculation-measurement of the basic scale’s size. This issue became the reason of a wide discourse between important theoreticians of the 19th century through the daily and periodical press and led to the convocation of the Music Committee of 1881. See Ανδρίκος, 135-145.
Πρεβεζάνικες σελίδες σε εφημερίδες της προαπελευθερωτικής περιόδου
Authors: Κωστούλας Κωνσταντίνος Χρ.
Published: December 2021

Σταχυολογώντας μερικές από τις ειδήσεις της εφημερίδας Ἰωάννινα,αλλά και μερικές άλλες ελληνικές εκδόσεις, για την Πρέβεζα και την περιοχή,στοιχειοθετείται ένα μικρό χρονικό, με αυτές τις καταγραφές να αποτελούνλίγες σελίδες πρεβεζάνικης ιστορίας. Τις καταχωρούμε όπως βρέθηκαν με ταστοιχεία της χρονολόγησης, και όπου χρειάζεται με κάποιο σχολιασμό ναακολουθήσει το δημοσίευμα.
Πρέβεζα 1940: Η ανεκπλήρωτη απόβαση. Ιστορικό μιας συνεχούς αποτυχίας
Authors: Ιωνάς Σπύρος
Published: December 2021

Κατά τη σχεδίαση της ιταλικής επίθεσης στην Ελλάδα του 1940 αλλά και κατά τη διάρκεια του Ελληνοϊταλικού πολέμου, από την έναρξή του και μέχρι τη λήξη του, το ενδιαφέρον της ιταλικής ηγεσίας προς την Πρέβεζα θα είναι σταθερό και η τύχη της πόλης, σαν στόχου στα ιταλικά στρατιωτικά σχέδια, θα αλληλοεμπλέκεται συνεχώς με αυτήν των Επτανήσων, σε μια αδιάκοπη αλληλουχία επιβεβαιώσεων και ματαιώσεων σχεδίων απόβασης.  Το κείμενο ερευνά το ενδιαφέρον της ιταλικής ηγεσίας προς την Πρέβεζα κατά τον Ελληνοϊταλικό πόλεμο καθώς και τα πολεμικά γεγονότα που διαδραματίστηκαν γύρω από αυτό το θέμα. Βασίζεται κατά μεγάλο μέρος σε δύο πρωτογενείς πηγές, το πολεμικό ημερολόγιο της Ανώτατης Ιταλικής Διοίκησης και τα πρακτικά των συσκέψεων του Αρχηγού Γενικού Επιτελείου.
Το κάστρο του Παντοκράτορα. Πρόταση αποκατάστασης, ανάδειξης και επανάχρησης
Authors: Σαρρή Ελισάβετ Π.
Published: December 2021

Αντικείμενο της εργασίας, αποτελεί το κάστρο του Παντοκράτορα στην Πρέβεζα, ένα σημαντικότατο οχυρωματικό έργο του 19ου αιώνα, η ίδρυση και λειτουργία του οποίου είναι απόλυτα συνυφασμένη με την πολιτική ιστορία της τότε ελληνικής επικράτειας και ιδιαίτερα της πόλης της Πρέβεζας.
Φωνές, Οιδίποδας, Γράμμα
Authors: Γαλάνη Ρούλα
Published: December 2021

Ποίηση
Το Φευγιό
Authors: Μάργαρης Βασίλης Κωνσταντίνος
Published: December 2021

Διήγημα
Αγία Παπαλίνα η καλλονή (εξώφυλλο)
Authors: Νιάρχος Θανάσης
Published: December 2021

Φωτογραφία εξωφύλλου του βιβλίου του Σπύρου Μπρίκου "Αγία Παπαλίνα η καλλονή"
Υδατογραφία
Authors: Νικολάου Αναστασία
Published: December 2021

Ποίηση
Καρυωτάκης
Authors: Πάσχος Παντελής Β.
Published: December 2021

Ποίηση
Σούρουπο στο λιμάνι
Authors: Χατζηθεοδώρου Λευτέρης
Published: December 2021

Ποίηση
Σημείωμα Συντακτικής Επιτροπής
Authors: Επιτροπή Συντακτική
Published: December 2021

Σημείωμα Συντακτικής Επιτροπής περιοδικού Πρεβεζάνικα Χρονικά
Η συλλογική πολιτική και πολιτιστική κίνηση στην Πρέβεζα την περίοδο 1908-1912*
Authors: Μπέτσος Οδυσσέας
Published: December 2021

Δεν αναφέρεται περίληψη
Οι Πρεβεζάνοι αξιωματικοί και η δράση τους κατά την κατοχή και την αντίσταση
Authors: Μουστάκης Γιώργος Ιασ.
Published: December 2021

Δεν αναφέρεται περίληψη
Ο προσφυγικός πληθυσμός της Ανατολικής Θράκης στην Πρέβεζα το 1922
Authors: Παπαθανασοπούλου Ιωάννα
Published: December 2021

Δεν αναφέρεται περίληψη
Έκθεση αρχειακού υλικού "1912-2012:100 χρόνια ελεύθερη Πρέβεζα"
Authors: Σκλαβενίτης Σπύρος
Published: December 2021

Παρουσίαση της έκθεσης του αρχειακού υλικού "1912-2012:100 χρόνια ελεύθερη Πρέβεζα" στο πλαίσιο εορτασμού για τη συμπλήρωση 100 χρόνων απόο την απελευθέρωση της Πρέβεζας
William Goodison και Richard Burgess. Δύο λιγότερο γνωστοί περιηγητές στην Πρέβεζα και τη Νικόπολη
Authors: Καράμπελας Νίκος Δ.
Published: December 2021

Στο άρθρο παρουσιάζονται τα κείμενα δύο περιηγητών, οι οποίοι επισκέφθηκαν την Πρέβεζα το πρώτο μισό του 19ου αιώνα. Πρόκειται για τους William Goodison, Ιρλανδό στρατιωτικό γιατρό, και τον Richard Burgess, Άγγλο θεολόγο.Ο πρώτος έφτασε στην Πρέβεζα τον Ιούνιο του 1818, όταν στην περιοχή κυριαρχούσε ακόμη ο Αλή πασάς Τεπελενλής. Ο Goodison μας παρέχει σημαντικά στοιχεία για τις οχυρώσεις της πόλης, το παραθαλάσσιο σεράι του Αλή πασά, το οθωμανικό τέμενος, και την καθημερινή ζωή στην πόλη. Η επίσκεψή του στον ερειπιώνα της αρχαίας Νικόπολης περιγράφεται εν συντομία,Ο δεύτερος επισκέφθηκε την Πρέβεζα και την αρχαία Νικόπολη τον Μάιο του 1834, συνοδεύοντας, ως παιδαγωγός, τρεις γόνους της βρετανικής αριστοκρατίας: τον λόρδο George Paget, τονThomas Knox και τον John Butler-Clarke-Southwell-Wandesford. Έφτασαν στην Πρέβεζα από τη Θεσπρωτία, ακολουθώντας μια ασυνήθιστη διαδρομή, μέσα από τη λάκα της Ξένης, βόρεια του χωριού Χειμαδιό. Περιγράφει την πόλη όπως την είδε 14 χρόνια μετά την εκδίωξη του Αλή πασά και την κατάληψή της από τα οθωμανικά στρατεύματα.
Συβαρίτης; Ενηλικίωση
Authors: Γαλάνη Ρούλα
Published: December 2021

Ποίηση
Ο Διγενής στην κορφή του ρολογιού. Μια εις Άδου κάθοδος στην ιστορία της πόλης
Authors: Παπαδημητρίου Απόστολος Σπ.
Published: December 2021

Διήγημα. Ο βασικός πυρήνας της ιστορίας του διηγήματος βασίζεται σε πραγματικά γεγονότα που συντηρήθηκαν από προφορικές διηγήσεις παλαιότερων συγγενών του συγγραφέα
A Randomized controlled trial of the Effect of intraVenous iron on Anaemia in Malawian Pregnant women (REVAMP): Statistical analysis plan
Authors: Harding Rebecca , Ataide Ricardo , Mwangi Martin N , Simpson Julie A , Mzembe Glory , Moya Ernest , Truwah Zinenani , Nkhwazi Brains Changaya , Mwabinga Mphatso , Nkhono William , Phiri Kamija S , Pasricha Sant-Rayn , Braat Sabine
Published: December 2021

Background: Anaemia affects more than half of Africa’s pregnancies. Standard care, with oral iron tablets, often fails to achieve results, with compliance and gastrointestinal side-effects being a significant issue. In recent years, intravenous iron formulations have become safe, effective, and quick to administer, allowing the complete iron requirements of pregnancy to be provided in one 15-minute infusion. The Randomized controlled trial of the Effect of intraVenous iron on Anaemia in Malawian Pregnant women (REVAMP) will evaluate whether a modern intravenous iron formulation, ferric carboxymaltose (FCM), given once during the second trimester is effective and safe in improving maternal and neonatal outcomes for treatment of moderate to severe anaemia in sub-Saharan Africa.  

The objective was to publish the detailed statistical analysis plan for the REVAMP trial prior to unblinding the allocated treatments and performing the analysis.  

Methods: REVAMP is a multicentre, two-arm, open-label, parallel-group randomized control trial (RCT) in 862 pregnant women in their second trimester. The trial statistician developed the statistical analysis plan in consultation with the trial management team based on the protocol, data collection forms, and study outcomes available in the blinded study database.  

Results: The detailed statistical analysis plan will support the statistical analyses and reporting of the REVAMP trial after unblinding the treatment allocations.  

Conclusions: A statistical analysis plan allows for transparency as well as reproducibility of reporting and statistical analyses.
Network Leadership: on the Mechanism of Political Mobilization
Authors: Achkasova V. , Dobrovol'skaya Yu.
Published: December 2021

The article attempts to develop an approach to describing the mechanism of network political mobilization by political leaders. The purpose was achieved through a pilot empirical study. In order to obtain data on the participants, means and methods of political mobilization in the network space the method of questioning was used. The audience of the research is students of universities of large Russian cities in the number of 83 people. Participants of research are selected by a method of purposeful sampling. The objectives of the analysis are also the communication environment of political leaders in the network space, technologies, methods and system of evaluation of interaction in social media. The results of the research confirmed the hypothesis of the deployment process of the phenomenon of network political leadership, identified and described trends in the communications of network leaders. Authors offered a methodology of research of network mobilization process through a prism of parameters of network involvement and online political support. The presence of these elements makes it possible to launch the mechanism of political mobilization in social networks. In the long term, the data obtained and the developed tools for empirical research can be useful in conducting large-scale political research, in particular, studying the phenomenon of political recruiting.
Politicization of Socially Significant Topics in Advertising Communications
Authors: Rafikov Artur
Published: December 2021

The key objective of the study is to identify strategies for politicizing socio-economic issues in political advertising communications. The method of critical discourse analysis in the tradition of N. Fairclough is used: an interpretive, explanatory method involving the study of discourses as forms of social practice. The result of the study was the identification of the main politicization strategies used by candidates for the post of President of the Russian Federation in 2012 V.V. Zhirinovsky and G.A. Zyuganov in advertising communications: the use of oppositions ("before - now"; "past - present - future"); appeal to the past, to the history of the country; symbolization of the current socio-economic situation of the country; distancing the subject of communication from the unsatisfactory results of the current government; the use of humor (including unconsciously); identification of their lifestyle with the lifestyle of voters – "millions of people"; the use of informal discourse when addressing voters; appeal to their economic and everyday practices; imitation of journalistic format; linking changes in the socio-economic situation with changes in the political sphere. The use of discursive practices that are not shared by the entire population can also provoke the politicization of the issue under discussion. The theoretical significance of the research is manifested in the approbation of the method of critical discourse analysis (in the tradition of N. Ferklo). It allows you to analyze political advertising communications at three levels: textual, discursive and social.
Piękna Madonna Gdańska i Madonna z kaplicy św. Anny we Fromborku w świetle badań petrograficznych
Authors: Bartz Wojciech , Jakubek-Raczkowska Monika
Published: December 2021

Studium jest poświęcone identyfikacji materiałoznawczej oraz potwierdzeniu wspólnoty warsztatowej i proweniencji stylu dwóch rzeźb z ok. 1420–1430, zachowanych z dziedzictwa artystycznego państwa zakonnego w Prusach: Pięknej Madonny Gdańskiej (w Bazylice Mariackiej w Gdańsku) i – silnie uszkodzonej – rzeźby Madonny z kaplicy św. Anny we Fromborku (obecnie w zbiorach Muzeum Mikołaja Kopernika we Fromborku). Oba posągi, odosobnione na tle sztuki regionu przez swój kamienny surowiec, formę artystyczną oraz monumentalną skalę, zostały odkute z tej samej skały, pozyskanej najpewniej z kamieniołomów w dorzeczu Skaldy, w jednym warsztacie o zdecydowanie zachodniej formacji artystycznej. Choć rozpoznanie materiału nie rozstrzyga definitywnie o genezie artystycznej rzeźb, źródeł stylu ich obu można dzięki niemu o wiele pewniej niż dotychczas upatrywać w sztuce franko-niderlandzkiej. Nie można ostatecznie zawyrokować, czy rzeźby te powstały na Pomorzu w warsztacie niderlandzkiego twórcy, dla którego sprowadzono materiał pozyskiwany na obszarze Hainaut-Artois / Flandrii francuskiej, czy też są importami z południowych Niderlandów – ta druga możliwość, łącząca pochodzenie surowca i pochodzenie formy, wydaje się jednak dużo bardziej prawdopodobna. Tekst prezentuje szczegółowo metodykę badań próbek pobranych z obu rzeźb i płynące z nich wnioski, dające dowód wysokiego potencjału analiz petrograficznych dla historii sztuki, a także pogłębia charakterystykę porównawczą obu zabytków na tle rzeźby europejskiej pierwszej połowy XV wieku. Celem studium jest z jednej strony określenie ich proweniencji artystycznej w konfrontacji z wynikami badań skały (niezwykle istotne zarówno dla badań regionalnych, jak i dla światowych studiów nad stylem pięknym); z drugiej – wprowadzenie do szerszej dyskusji nad geografią złóż i tworzywem rzeźby średniowiecznej nieznanego dotąd materiału badawczego (z pełną dokumentacją badań petrograficznych, umożliwiającą dalsze analizy porównawcze).
Handel pigmentami miedziowymi ze złóż świętokrzyskich w świetle źródeł archiwalnych
Authors: Witkowski Michał , Svorová Pawełkowicz Sylwia
Published: December 2021

W regionie geograficznym Gór Świętokrzyskich, w pobliżu Kielc, znajdowały się dwa ważne w okresie staropolskim ośrodki wydobycia rud miedzi – położona w Paśmie Chęcińskim Miedzianka oraz leżąca w obecnej aglomeracji kieleckiej Miedziana Góra. Artykuł porusza zagadnienie handlu pigmentami miedziowymi (azurytem, malachitem i grynszpanem) pochodzącymi z przedmiotowych złóż na przestrzeni XVI–XVIII w. W źródłach archiwalnych informacje na temat handlu materiałami artystycznymi pojawiają się w dokumentach prawnych dotyczących przywilejów górniczych oraz aktach gospodarczych, w tym rachunkach dworów królewskich i biskupich, a także lustracjach dóbr królewskich i majątków biskupstwa krakowskiego oraz krakowskiej kapituły katedralnej. Cenne wiadomości o funkcjonowaniu kopalń pozyskano również z fragmentarycznie zachowanych w odpisach chęcińskich ksiąg żupniczych oraz akt miejskich, gdzie zawarte są również szczegóły dotyczące zarówno sprzedawców, jak i ich dłużników. Zebrane informacje wskazują, że pigmenty ze złóż świętokrzyskich wykorzystywano do dekoracji zamków królewskich w Krakowie i Warszawie oraz zamku wielkoksiążęcego w Wilnie, a niektóre z nich, jak np. malachit, eksportowano do Europy Zachodniej.
Udział polskiej młodzieży w życiu politycznym Królestwa Kongresowego w latach 1905–1918 w świetle relacji z epoki
Authors: Waingertner Przemysław
Published: December 2021

Przedmiotem artykułu jest próba rekonstrukcji zjawiska zaangażowania młodzieży polskiej w życie polityczne Królestwa Kongresowego w latach 1905–1918 w oparciu o relacje z epoki. Ich autorami są zarówno przedstawiciele ówczesnego młodego pokolenia, reprezentujący różne nurty polityczne, jak i dojrzali politycy, publicyści, działacze oświatowi i społeczni. Relacje te są nie tylko źródłem informacji o motywach politycznych wyborów i poczynań młodych Polaków w początkach XX w., roli i znaczeniu tego pokolenia w życiu politycznym Królestwa Polskiego, ale także o miejscu, jakie zajmowała młodzież w refleksji reprezentantów starszych generacji.
Zmarnowana dekada? Ekspansja inwestycyjna lat siedemdziesiątych XX wieku na tle polityki gospodarczej w okresie PRL
Authors: Koryś Piotr , Tymiński Maciej
Published: December 2021

W pierwszej połowie lat siedemdziesiątych XX w. pod rządami Edwarda Gierka w Polsce wprowadzono jeden z największych programów inwestycyjnych po II wojnie światowej. W jego realizacji kluczową rolę odgrywały technologie importowane z krajów wysokorozwiniętych oraz projekty inwestycyjne finansowane z zachodnich kredytów. Rezultaty modernizacji kraju, chociaż spowodowały krótkotrwałe przyspieszenie rozwoju, nie przyniosły oczekiwanych efektów.
Postępowanie w sprawach z zakresu prawa pracy i ubezpieczeń społecznych po nowelizacji Kodeksu postępowania cywilnego
Authors: May Joanna
Published: December 2021

Artykuł jest poświęcony przedstawieniu zmian wprowadzonych Ustawą z dnia 4 lipca 2019 r. oraz Ustawą z dnia 16 maja 2019 r. o zmianie ustawy – Kodeks pracy oraz niektórych innych ustaw, ale jedynie w obszarze mającym wpływ na obecny kształt postępowania odrębnego w sprawach z zakresu prawa pracy i ubezpieczeń społecznych. Przyjętą przez autorkę kolejność omawianych zmian wyznaczają etapy postępowania w sprawach z zakresu prawa pracy i ubezpieczeń społecznych. Artykuł zasadniczo koncentruje się na przedstawieniu najważniejszych zmian k.p.c., autorka jednak nie stroni od ich oceny.
Czy wniesienie powództwa oczywiście bezzasadnego w rozumieniu art. 191(1) k.p.c. przerywa bieg przedawnienia?
Authors: Tomczak Tomasz
Published: December 2021

Prawodawca Ustawą z dnia 4 lipca 2019 r. o zmianie ustawy – Kodeks postępowania cywilnego oraz niektórych innych ustaw wprowadził do polskiej procedury cywilnej m.in. instytucję oddalenia powództwa jako oczywiście bezzasadnego (art. 191(1) k.p.c.). Celem niniejszego artykułu jest podjęcie próby odpowiedzi na pytanie: czy wniesienie powództwa oczywiście bezzasadnego w rozumieniu art. 191(1) k.p.c. przerywa bieg przedawnienia? Rozważania nad tym zagadnieniem prowadzą do wniosku, że odpowiedź na to pytanie powinna być negatywna.
Glosa do wyroku Wojewódzkiego Sądu Administracyjnego w Warszawie z dnia 12 stycznia 2021 r., sygn. II SA/Wa 1843/20
Authors: Gacek Paweł
Published: December 2021

Komentowany wyrok dotyczył zagadnienia związanego z przeniesieniem funkcjonariusza Policji do dalszego pełnienia służby w innej jednostce Policji lub innej miejscowości na podstawie art. 36 ust. 1 ustawy o Policji. Zdaniem sądu istota zagadnienia w tego rodzaju sprawie sprowadza się do ustalenia, czy stanowisko służbowe, na które przeniesiono i mianowano policjanta, jest stanowiskiem równorzędnym z poprzednio przez niego zajmowanym. W glosie krytycznie odniesiono się do tego poglądu wyrażonego przez sąd. Wskazano, że art. 36 ust. 1 ustawy o Policji precyzyjnie wytycza granicę sprawy administracyjnej dotyczącej przeniesienia policjanta do pełnienia służby w innej jednostce organizacyjnej Policji lub w innej miejscowości. Jest nią wyłącznie przeniesienie, które nie łączy się w żaden sposób z automatycznym mianowaniem policjanta na określone stanowisko służbowe w związku z tym przeniesieniem.
Piętnastowieczne listy kandydatów do święceń z archidiecezji gnieźnieńskiej
Authors: Kozak Adam
Published: December 2021

W artykule podjęto próbę wskazania okresu, kiedy w polskiej prowincji kościelnej rozpoczęto prowadzenie rejestrów osób przyjmujących święcenia duchowne i określenia formy kancelaryjnej najstarszych wykazów. W tym celu omówiono cztery niepublikowane dotąd przekazy, które udało się zidentyfikować jako XV-wieczne listy kandydatów do święceń. Pierwszy zachował w rękopisie Biblioteki Jagiellońskiej o sygnaturze 143 III, trzy kolejne zaś odnalezione zostały w 2015 r. wśród dokumentacji konsystorza gnieźnieńskiego i przechowywane są obecnie w zbiorach Archiwum Archidiecezjalnego w Gnieźnie. Artykuł dopełnia edycja krytyczna prezentowanych wykazów.
Siedemdziesiąt pięć lat serii II Pomników dziejowych Polski
Authors: Gąsiorowski Antoni
Published: December 2021

Pomniki dziejowe Polski (Monumenta Poloniae historica, MPH) to sześciotomowe wydawnictwo (1864–1893; reprint 1960–1961) zbierające źródła narracyjne dotyczące polskiego średniowiecza i czasów wczesnonowożytnych. Do dziś jest jedną z podstawowych pozycji w warsztacie polskiego mediewisty. Po II wojnie światowej rozpoczęto reedycję poszczególnych zabytków, powołując do życia MPH nova series. Reedycji poddano dotąd ok. 30% zawartości starych MPH. Przedmiotem rozważań autora są dalsze losy serii.