bluuebunny/crossref_metadata_2025 huggingface dataset:
Progesterone Receptor Expression in Histopathological Subtypes of Beningn Orbitocranial Meningiomas
Authors: Lassie Naima , Supartoto Agus
Published: January 2024

Background: Meningioma is the most common benign brain tumor which has several subtypes histopathologically.Previous studies indicate that progesterone receptors (PR) plays important role in thetumor behavior and may determine its prognosis. However, whether different subtypes show similarPR expression remains unclear. This study aimed to evaluate PR expression, in many histopathologicalsubtypes of benign orbitocranial meningiomas.Methods: Eighty one patients visiting Sardjito General Hospital with benign orbitorcranial meningioma(WHO grade I) between 2010-2013 were included. Tumor specimens were obtained for histopathologyassessment and PR expression using immunohistochemistry examination, including the intensity ofexpression.Results: There were 72 (88.9%) women and 9 (22.2%) men, aged between 21-72 years old. PR waspositive in 71.6% patients (76.4% women). There were different subtypes of meningioma as follows:meningotheliomatous (44.4%), transitional (33.3%), and fibrous (14.8%). PR was positive in 72.2%meningotheliomatous, 70.4% in transitional, and 66.7% fibrous subtype. Other subtypes of benignmeningioma (microcystic, angiomatous, lymphoplamocyte-rich, and metaplastic) were not found inour study. But, this finding was not statistically significant using Pearson correlation test (p>0.05).Conclusion: The majority of patients with meningioma were women. The most common histopathologicalsubtypes were meningotheliomatous and transitional, of which more than 70% was PR positive.However, there were very little variations in PR expression among different subtypes of benign orbitocranialmeningioma.Â Keywords: orbitocranial meningioma, progesterone receptor (PR) expression, histopathological subtype
Opening the New Chapter in Our Organization
Authors: Gondhowiardjo Tjahjono D.
Published: January 2024

No abstract available
Transcranial Supraorbital Approach for Tumor Removal of Spheno-Orbital Meningioma with Favorable Clinical Outcomes
Authors: Noor Nina Asrini , Anggraini Neni , Mutmainah Mutmainah , Aman Renindra Ananda
Published: January 2024

Background: To describe and evaluate the surgery results regarding resectability and clinical outcomes oftranscranial supraorbital approach for tumor removal of spheno-orbital meningiomaCase Illustration: A 58-year-old woman presented with proptosis of the right eye since 9 years prior.At initial examination, visual acuity was 6/15 with significant nasal visual field defect. There wereprominent proptosis and inferior globe displacement of the right eye with no palpable mass. A frontoparietalbone deformity was also observed. CT scan examination revealed hyperostosis of sphenoid,frontal, and temporal bone with extensive intraorbital mass with contrast enhancement suggestive ofmeningioma. Incisional biopsy was the performed and confirmed the histopathological diagnosis ofmeningothelial meningioma (WHO grade 1). Transcranial supraorbital in conjunction with lateralorbitotomy was performed in this patient as the definitive treatment for tumor removal of sphenoorbitalmeningioma. Craniotomy and opening of orbital roof were carried out by neurosurgeon toexpose intraorbital region. Total tumor removal was than completed.Conclusion: Transcranial supraorbital approach is an effective surgery for spheno-orbital meningiomaremoval as it offers excellent exposure. A radical resection through transcranial approach can be achievedwith low morbidity, providing a significantly improved clinical outcome in long term period. In thiscase, the spheno-orbital meningioma was grossly resected totally with excellent visual outcome andacceptable cosmetic appearance.Keywords: spheno-orbital meningioma, transcranial approach, tumor resection
Treatment of Central Serous Chorioretinopathy with Carbonic Anhydrase Inhibitor
Authors: Witjaksana Riani , Sumual Vera
Published: January 2024

Background: To report a case of central serous chorioretinopathy at Ophthalmology Department ofRD Kandou Hospital, Manado.Case Illustration: A 51-year-old male patient came to hospital with complaint of sudden blurredvision in his right eye since 1 week before admission. He felt there was a black shadow in the center ofhis right eye. He had history of uncontrolled hypertension and smoking for the last 30 years.Examination result showed that visual acuity of his right was 1/60. On confrontation test, there wascentral scotoma in the right eye with normal extra-ocular motility and he had a relative afferentpupillary defect. On fundus examination, there was an area of pigment near the fovea and elevatedcentral macula and consisted with subretinal fluid. Patient was treated with carbonic anhydraseinhibitor (CAI) as long as one week. During the follow-up, there was an improvement in his visual acuity.Conclusion: After treatment of acetazolamide as long as one week, CSCR looked improved in visualacuity and decreased subretinal fluid. Generally, CSCR have a good prognosis.Keywords: central serous chorioretinopathy, acetazolamide, subretinal fluid
Pituitary Macroadenoma Treated with Cabergoline: the Role of Neuro-Ophthalmic Examination in Diagnosis and Follow Up Management
Authors: Lote Yunita Latif , Umar Batari T , Mansyur Yunita
Published: January 2024

Background: To describe the importance of neuro-ophthalmic examination on pituitary macroadenomapatient with bitemporal hemianopia and treated with cabergoline.Case Illustration: A 50-year-old female came with blurry vision on both eyes. She had 20/40 and 20/30vision right eye and left eye respectively, no RAPD, no limitation of gaze, anterior and posterior segmentswere unremarkable. She had superior bitemporal defect expanding to inferior quadrant of visual fieldby Humphrey. MRI scan showed suggestive pituitary macroadenoma with bleeding and supression tosuperior chiasm. The prolactin level was elevated and she was then referred to endocrinologist andgiven dopamine agonist (cabergoline) treatment. Six months after cabergoline therapy, patientâ€™s visualacuity had improved to 20/25 on both eyes, no progression on Humphrey visual field defect and alterationin size of the macroadenoma from MRI.Conclusion: A characteristic visual field defect can be a first sign for pituitary macroadenoma. Surgicalare not always necessary. Medicine therapy can be beneficial for secreting pituitary macroadenoma.Ophthalmology examination can help assessing the prognosis of the disease.Keywords: bitemporal hemianopia, pituitary macroadenoma, prolacin, cabergoline
Efficacy and Safety of Imiquimod 5% as Primary Therapy in Management of Nodular Basal Cell Carcinoma of the Eyelid
Authors: Samira Cut Putri , Andrisa Rossalyn Sandra
Published: January 2024

Background: To evaluate the efficacy (complete resolution, tolerability, and recurrance of BCC) andsafety (adverse effect during and after treatment) of imiquimod 5% cream as primary therapy inmanagement of nodular basal cell carcinoma.Methods: Journal articles published that were published between 2007 and 2011 related to themanagement of eyelid nodular basal cell carcinoma with imiquimod 5% cream were reviewed.Results: Of all 6 articles: 1 article was randomized trial study; 1 article was case series study; whilethe others were prospective studies. The rate of complete resolution with imiquimod 5% therapy wasoverall high with range 80-100% between all studies. Four studies reported tolerability of imiquimodtherapy assessed by ophthalmologist also range from 80-100%. No occurance of relapse were reportedin all studies. Skin reaction is the most common adverse effect seen with the rate widely variedbetween 53.5% to 100%. Skin reaction could be seen as erythema, crusting, or scabbing in the site ofimiquimod application during and after treatment of the therapy. The other side effects were skinulceration (40-55.5%), keratitis (15%), conjunctivitis (13.3-40%), and ocular discomfort (60%). Nosystemic side effect were reported in all studies.Conclusion: Imiquimod 5% cream gains good evidence of efficacy and safety in treating nodular eyelidand periocular BCC. Imiquimod may be used as first-line treatment in patients with small eyelidnodular BCC located in patients who refuse surgery or have existing pathologies that contraindicatesurgery.Keywords: imiquimod 5% cream, basal cell carcinoma of the eyelid or periocular
Comparison of Clinical Outcomes between Phacoemulsification and Laser Peripheral Iridotomy in the Spectrum of Primary Angle Closure Diseases of the Eye
Authors: Panjaitan Manoa , Artini Widya
Published: January 2024

Background: To compare clinical outcome between phacoemulsification and laser peripheral iridotomyin the spectrum of primary angle closure eyes.Methods: A literature review of databases were retrieved online through Pub-med, Clinical Key, andScience Direct, using keywords of â€˜primary angle closureâ€™, â€˜primary angle closure glaucomaâ€™, andâ€˜acute primary angle closureâ€™. In addition, all literatures involving the use of laser peripheral iridotomy(LPI) or phacoemulsification as a treatment in PAC diseases were included. Publications and journalsbefore the year 2000 were excluded.Results: There were 18 articles that fulfilled our inclusion criteria. All of the studies showed a decreasein IOP following cataract extraction or LPI, compared to baseline. This study also showed that thephacoemulsification group gave a significantly larger angle width increment when compare to LPI.When directly compared between phaco to LPI, the number of topical glaucoma medication was moredecreased in the phaco group, meanwhile the need for additional glaucoma surgery was higher in theLPI group.Conclusion: Phacoemulsification with posterior chamber lens implantation is more effective procedurethan LPI in lowering IOP and preventing IOP rise in long term follow up in PAC diseases. That surgerywill reduce the number of additional glaucoma medication and further glaucoma filtering surgery.Despite of superiority in phacoemulsification treatment, LPI is still the mainstay of initial treatment,especially in PAC eye diseases without cataract.Keywords: spectrum of primary angle closure eye disease, phacoemulsification, laser peripheral iridotomy, angle width
Clinical Outcome of Intravenous Glucocorticoid and Rituximab in Moderate to Severe Thyroid Eye Disease
Authors: Dewiputri Salmarezka , Sidik M
Published: January 2024

Background: Thyroid eye disease (TED) is the most common extrathyroidal manifestation of Gravesâ€™disease, also a serious and potentially sight-threatening. Current treatment method by using glucocorticoidis still unclear. Rituximab is a biological agent that has been used successfully. In the literatures, thepotential drug use for TED has been discussed but there is no guidelines published outliningrecommendations. The objective of this literature review is to evaluate the efficacy and safety ofglucocorticoid and rituximab for the treat-ment of TED in terms of clinical outcome, side effect, andrelapse rate.Methods: The literature search was conducted from Google Scholar, MEDLINE database using Pubmedfor journal articles that were published and related to the use of intravenous glucocorticoid andimmunobiologic therapy in Gravesâ€™ ophthalmopathy.Results: A total of 10 articles were reviewed in this paper. Six studies evaluated IVGC treatment, 3studies evaluated rituximab treatment, 1 study evaluated and compared IVGC and rituximab treatment.Most of the reviewed studies reported improvement on proptosis, while some studies reportedimprovement in proptosis by using rituximab.Conclusion: Rituximab is as effective as IVGC in decreasing proptosis. Rituximab was significantlybetter and earlier that IVGC in reducing CAS.Keywords: intravenous glucocorticoid, rituximab, thyroid eye disease
Efficacy and Safety Comparison among Rigid Gas Permeable Contact Lens Correction for Keratoconus
Authors: Valenchia Valenchia , Rahayu Tri
Published: January 2024

Background: Rigid gas-permeable contact lenses (RGP CL) are commonly used to manage moderate tosevere keratoconus. The range of RGP CL type currently available for the successful optical correctionof keratoconus has greatly expanded. We compared the efficacy and safety of available RGP CL basedon visual acuity (VA), keratometry, comfort score, and adverse event.Methods: Literature search on RGP CL and keratoconus retrieved 37 citations from 2010-2015. Ninearticles were selected as relevant to our purpose.Results: All studies showed improvement of VA following RGP CL wearing. Greatest improvementwas seen in Rose K CL (.5 - .36) in naÃ¯ve CL patient and Twinbel bevel toric in refitting CL patient(.22). All studies reported lower mean Î”K post fitting RGP CL than pre-fitting. Greatest difference ofmean Î”K pre and post-fitting was observed in YK lens (.72). The most comfortable lens was Rose K(91.5%) followed by Soper CL (87.9%) and Twinbel bevel toric (64.4%). Punctuate corneal stainingfound in a considerable amount with YK lens patient.Conclusion: Among 5 types of RGP CL available now for keratoconus, Rose K provided greatestBCVA improvement in naÃ¯ve CL patient whereas Twinbel bevel toric in refitting patient. YK lensgave greater changes in keratometry post-fitting RGP CL. The most comfortable lens for patient isRose K lens. The most common adverse event of CL wear is punctuate corneal staining in YK lenspatient.Keywords: rigid gas permeable contact lens, keratoconus
Inter-observer Agreement in Fundus Photography for Diabetic Retinopathy Screening in Primary Health Care
Authors: Arianti Alia , Andayani Gitalisa A
Published: January 2024

Background: To assess the agreement between a group of trained non-physician ophthalmic careproviders as primary grader, and vitreoretina specialist as secondary grader, in the interpretation ofsingle-field 45o, non-mydriatic digital fundus image for diabetic retinopathy (DR) screening in primaryhealth care.Methods: This is an analytic, retrospective study. A total of 117 fundus images of diabetic patientswere graded by primary grader, followed by secondary grader using the modified National ScreeningCommittee (NSC) as a guideline. Kappa statistics and Intraclass Correlation (ICC) were used for thereliability assessment of photograph quality, DR presence and classification, presence of maculopathyand photocoagulation, severity level, and presence of vision-threatening diabetic retinopathy (VTDR).Diagnostic values of fundus image interpretation by primary grader in detecting DR using secondarygrader as the reference standard were also assessed.Results: Agreement for DR classification and its severity level was good (ICC 0.654; 0.642). Fairagreement was found for presence of maculopathy and VTDR (Îº 0.368; ICC 0.595). Slight agreementwas found for photograph quality (Îº 0.170). The percentage agreement in identifying DR was 29.9%.Sensitivity and specificity of fundus image interpretation by primary grader in DR and VTDR detectionwere 52.24% and 71.43%, 54.55% and 95.12%, consecutively.Conclusion: The reliability of primary grader for interpreting single-field fundus photography in DRscreening has not reached the ideal result in this study (Îº more than 0.6 in all variables). Acomprehensive training with continuing education is essential for non-physician personnel, to ensurethe reliability of DR screening program using single-field fundus photography.Keywords: diabetic retinopathy screening, interobserver agreement, kappa value, intraclass correlation.
Intraocular Pressure Changes After Selective Laser Trabeculoplasty (SLT) in Open-Angle Glaucoma
Authors: Mayasari Amalia , Cahyono Maharani
Published: January 2024

Background: Selective laser trabeculoplasty (SLT) use laser to selectively target pigmented trabecularmeshwork without producing collateral damage to adjacent non-pigmented cells or structures. A previousdata suggests that SLT is effective at every stage of open-angle glaucoma (OAG). SLT can be used asa first-line therapy, alternative to medical therapy, or as an adjunctive therapy to topical glaucomadrops. The aim of this study was to determine the changes in intraocular pressure (IOP) after SLT inpatients with OAG.Methods: Design of this research was cohort-prospective study. Twenty-six eyes of 18 patients withOAG were participated in this study. All the patients were treated with 180o SLT to the temporaltrabecular meshwork and followed by 180o SLT to the nasal trabecular meshwork 1 week after the firsttreatment. A frequency-doubled (532 nm) Q-switched Nd:YAG laser with a 400 Î¼m spot size wasused to deliver 0.4-1.0 mJ of energy for 0.3 ns to perform the procedure. Additionally, IOP in thetreated eye was assessed and measured with Goldman applanation before SLT, and 1 hour, 1 week,and 2 weeks following complete SLT. All patientes were given corticosteroid (prednisolone acetat 1%eyedrop) 4 times a day for 7 days after SLT to prevent elevation of IOP caused by inflammation.Results: The average pre-SLT IOP were 19.94 mmHg. The mean IOP 1 hour post-SLT was slightlyincrease. IOP 2 weeks after complete SLT showed a significant decrease compared to before SLT(Wilcoxon-test, before: p=0.033; 1 hour: p=0.915; 1 week: p=0.098; 2 weeks: p=0.009)Conclusion: Intraocular pressure lowering effect was significant at 2 weeks after SLT treatment. SLTeffectively reduces IOP in open-angle glaucoma. It can be used as a primary or adjunctive therapy inpatient with open-angle glaucoma.Keywords: obstructive MGD, quality of meibum, ocular surface damage
Correlation between Meibum Quality and Ocular Surface Staining in Obstructive Meibomian Gland Dysfunction
Authors: Hikmawati Ike , Dahlan M Rinaldi , Heryati Susi
Published: January 2024

Background: Obstructive Meibomian gland dysfunction (MGD) leads to a decreased availability ofmeibomian lipid at the ocular surface that could result in ocular surface damage due to increasedevaporation of the aqueos layer of the tear film. Alteration of meibomian oil (meibum) is one of thecausative factors of the obstructive process and the sign of the obstruction as well.Methods: This was a cross-sectional study using Spearmanâ€™s Rank Correlation Coeeficient (rs) to findcorrelation between meibum quality and the ocular surface damage. Subjects were patients withobstructive MGD selected consecutively in Infection and Immunology Unit of Indonesia National EyeCenter, Cicendo Eye Hospital. There were 48 eyes from 29 subjects comprised 28 inflamed MGD and20 non-inflamed MGD. Meibum quality was assessed by performing digital expression on eightmeibomian glands located on the lower lid. Ocular surface damage was done by performing cornealstaining using fluorescein eye drop and conjunctival staining using Lissamine Green strip. The stainingresults were then documented using camera of slit lamp biomicroscopy and based on the documentation,scoring of the ocular surface staining was done using National Eye Institute/Industry (NEI)scheme/diagram.Results: This study showed no correlation (rs: -0.067) between meibum quality and ocular surfacedamage (p=0.652). Statistical analysis was also done on subjects categorized based on inflammationon the eyelid and there was found correlation (rs: 0.238) between meibum quality and ocular surfacedamage in inflamed MGD (p=0.312).Conclusion: There is no correlation between the quality of meibum and ocular surface staining.Keywords: obstructive MGD, quality of meibum, ocular surface damage
Age-Related Macular Degeneration Cases in Prof. RD Kandou General Hospital, Manado
Authors: Santoso Inga , Sumual Vera
Published: January 2024

Background: To report the data of patients with age-related macular degeneration (AMD) at Vitreo-Retina Division of Ophthalmology Department of Prof. RD Kandou General Hospital, Manado.Methods: This study was descriptive retrospective using medical records at the OphthalmologyDepartment of Prof. RD Kandou General Hospital, Manado period of January 2014 until June 2016.The subjects of research were the medical records of patients diagnosed with age-related maculardegeneration.Results: Of 27 patients, 14 (51.9%) were male and 13 (48.1%) were female with age ranging from 41to 81 years old. By type of AMD, the distribution was 85.2% dry and 14.8% wet AMD. Among therisk factors of AMD were hypertension in 12 patients (44.4%), diabetes mellitus in 2 patients (7.4%),and both hypertension and diabetes mellitus in 3 patients (11.1%).Conclusion: The number of patients diagnosed with AMD was 27 patients, with insignificant genderdifference. Most of the patients fell on the 61 to 71 years old group (48.2%), with majority type weredry AMD. Hypertension was the most influential risk factor.
Clinical Characteristic and Management of Central Serous Chorioretinopathy
Authors: Rhendy Rio , Victor Andi Arus
Published: January 2024

Background: Central serous chorioretinopathy (CSCR) is an abnormality in posterior segment of theeye, characterized by detachment of retinal neurosensory caused by localized accumulation of serousfluid. CSCR is commonly found in male (90%) with age ranging of 25 to 55 years old and oftenoccurs in white, Asia, and Hispanic. Subretinal fluid will be absorb spontaneously within 3-4 months,thus observation and risk factors modification are the initial management for CSCR for couple ofmonths. However, drugs use on CSCR can be considered to accelerate fluid resorption.Methods: This study is a descriptive-retrospective study, done in Vitreoretina Division of OphthalmologyDepartment, Cipto Mangunkusumo Hospital, Jakarta, from December 2015 to January 2016. Thesubjects were all CSCR patients, using medical records for data selection.Results: There were 90 patients with CSCR, but only 20 eyes from 19 patients could be included tothe study. Most of CSCR patients were male (84%), with age ranging from 25 to 55 years old, meanage of 40.31 years.Conclusion: Management of CSCR in Cipto Mangunkusumo Hospital gave significant improvementin UCVA and CMT.
Anti-Inflammation and Anti-Fibrotic Effects of Amniotic Membrane on Post-Trabeculectomy Conjunctiva (Experimental Research on Oryctolagus cuniculus)
Authors: Rihardini Listya Dyah , Suparman Suparman , Komaratih Evelyn
Published: January 2024

Background: To evaluate the effects of amniotic membrane transplantation on the modulation ofwound healing after trabeculectomy.Methods: Eighteen eyes of nine New Zealand rabbits: nine left eyes underwent glaucoma filteringsurgery, nine right eyes underwent trabeculectomy and amniotic membrane transplantation. Freshfrozen human amniotic membranes were transplanted above scleral flap, below the conjunctiva withthe stromal side-up. Daily examination of anterior segment were performed using hand held slit lamp.After 7 days, all eyes were enucleated and sent for histopathology examination to evaluate theinflammatory and fibroblast cells. The rabbits were terminated. Blebs were well formed until 7 days.Results: There were statistically no significant difference between two groups in quantity ofinflammatory cells (p=0.258) and fibroblast cells (p=0.436). The tendency in the treatment group,however, the Massonâ€™s Trichrome obtained less fibrosis (88.9%) compared to the control group(44.4%). Hematoxilin eosin staining revealed inflammatory reaction tends to be more severe than thecontrol group, suggesting a xenograft rejection.Conclusion: AMT is still potential as an alternative option to reduce fibrosis in glaucoma filteringblebs but need further research. In rabbits, human amniotic membrane elicited a xenograft reaction.Keywords: amniotic membrane, trabeculectomy, inflammation, fibrosis
Grave Ophthalmopathy, Menuju Penatalaksanaan yang Lebih Komperhensif
Authors: Sidik M
Published: January 2024

no abstract available
Devastating Lower Eyelid Squamous Cell Carcinoma in Patient with Xeroderma Pigmentosum
Authors: Rahayu Novia , Anggraini Neni , Andrisa Rossalyn Sandra
Published: January 2024

Background: Xeroderma pigmentosum (XP), an inherited condition of cellular sensitivity to ultraviolet (UV) radiation, mainly presents as cutaneous and ocular abnormalities, including neoplasia. This report aimed to demonstrate a devastating case of lower eyelid squamous cell carcinoma in XP patient.Case Illustration: Twenty four-year-old female with XP came with white plaque on both cornea. Excisional biopsy revealed a conjunctival intraepithelial neoplasia DD/ carcinoma in situ on right eye, and hyperplastic squamous epithelia on left eye. For nearly two years, she was lost to follow up, and revisited our clinic with a rapid growing, ulcerated, susceptible to bleed, red-yellowish mass, expanding to bulbar and tarsal conjunctiva, about 27 x 15 x 10 mm size, on her lower left eyelid, with restricted ocular movement. Incisional biopsy revealed a well-differentiated squamous cell carcinoma. In 6 weeks time, mass has grown to size 75 x 50 x 20 mm, and already infiltrated to superior eyelid and orbit.Conclusion: The nature of malignancy in XP patient is exceptionally progressive. Thorough education, close monitoring and early treatment is critical to prevent rapid deterioration and minimize possible impairment caused. Â Keywords: xeroderma pigmentosum, squamous cell carcinoma, eyelid squamous cell carcinoma, squamous cell carcinoma treatment
Prospective Comparative Study on Endothelial Corneal Cell After Cataract Surgery Using Torsional vs Longitudinal Phacoemulsification
Authors: Faranita Precisza Fanny , Sadasih Wisnu , Fanany A. Rizal , Maharani Maharani
Published: January 2024

Objectives: Our aim was to compare endothelial corneal cell changes after cataract surgery performed with Torsional and Longitudinal phacoemulsification in patient with senile cataract.
Methods: In this prospective study, the patients were divided into two groups, 24 eyes underwent cataract surgery using Torsional (OZil Infiniti Vision System, Alcon) and 23 eyes using Longitudinal phacoemulsification (Stelaris, Bausch & Lomb). Preoperative, 1 day, and 1-week post-operative examinations on endothelial corneal cells were performed using specular microscope. Cataracts were subdivided according to the LOCS III grading of nucleus. Intraoperative parameters using phacoemulsification time were evaluated.
Results: On the results of CCT at 1 day and 1-week post-operative, there were significant changes in group Torsional and Longitudinal 601±68.67; 562.22±45.48 (p=0.033) and 561,71±36,37; 519.52±79.93 (p = 0.015). However, there were no significant changes of CD, CV, HEX 1 day and 1 week post operatively between two groups. The phacoemulsification time was lower in group Torsional 17.11±15.86 seconds than group Longitudinal 18.53±15.46 seconds (p=0.595) but not significantly different.
Conclusions: Torsional phacoemulsification outperforms the Longitudinal with a lower phacoemulsification time on soft and medium cataracts, but the differences were not significant. Torsional caused more corneal edema at 1 day and 1 week postoperative significantly and more endothelial cell losses but insignificantly.
LATE-ONSET, BLEB-ASSOCIATED ENDOPHTHALMITIS CAUSED BY STAPHYLOCOCCUS AUREUS
Authors: Pangestika Riskha , Rahmi Fifin Luthfia , Maharani Maharani
Published: January 2024

Introduction: Bleb-associated endophthalmitis (BAE) is a potentially sight-threatening complications of trabeculectomy and is associated with poor visual outcome. BAE denotes an ocular infection with involvement of the vitreous, which usually develops months or years after glaucoma filtering surgery. The purpose of this case report was to present a case about late onset BAE caused by Staphylococcus aureus.
Methods: A 55-year-old male presented with a 3-days history of left eye pain, redness, hypopion decreased visual acuity and hypotony with Seidel test positive. He had a history of primary open angle glaucoma that was treated with a combined procedure of cataract surgery and trabeculectomy in the left eye ten years earlier. His visual acuity had decreased from 6/20 to light perception. This patient showed signs of hypotony, endophthalmitis, leak, and pain but no previous history of using anti-fibrotic agents. BAE causative organisms cultures grew the S.aureus, that frequent cause of acute-onset endophthalmitis. The patient underwent treatment with pars plana vitrectomy, vitreous taps, administered intravitreal antibiotic, and prescribed hourly topical antibiotic. Six months after his last treatment, his left eye shows no residual infection, and visual acuity increase to 1/60.
Results: One case of late onset BAE with visual improvement after early vitrectomy, intravitreal, oral and topical antibiotic treatment.
Conclusion: Despite the poor prognosis of BAE caused by S.aureus infection, after proper treatment can yield an adequate result, as demonstrated in this case.
SUCCESSFUL MANAGEMENT OF HYPERTROPIA RELATED THYROID EYE DISEASE WITH HEMI HANG-BACK PROCEDURE
Authors: Larasati Maria Debora Niken , Indriaswati Luki , Lutfi Delfitri
Published: January 2024

Introduction: Hypertropia in thyroid eye disease (TED) is uncommon condition which may cause visual and aesthetical problem with quality of life disturbance.
Case Illustration: A 44-year-old woman presented with a squint on the right eye with bilateral diplopia for 18 months. She had history of hyperthyroidism for two years which had been treated with thiamazole and propanolol for 1 year and methylprednisolone for 6 months. Visual acuity of both eyes was 20/20 with no sign of active inflammation and optic neuropathy. Ocular motility showed restriction in lateral and down gaze. Inferior restriction was found in forced duction test. Hypertropia of 40 prism diopters was remarkably seen in Krimsky test. We performed strabismus surgery after patient was in inactive stage and reach euthyroid state without treatment for 6 months. During surgery we found muscle enlargement and fibrous tissue of superior rectus muscle. Superior rectus recession for six milimeters with additional hemi-hang back procedure for two milimeters had been performed with significant improvement of diplopia. Ocular motility exercise was suggested to reach binocular vision.
Discussion: Hypertropia in TED was caused by extraocular muscle fibrosis due to inflammation and lymphocytic infiltration. Strabismus surgery was aimed at diplopia correction in primary position. Surgical procedure, extra ocular muscles in which surgery must be done and its surgical dosage should be considered carefully.
Conclusion: This case showed restrictive hypertropia in TED with distressing symptoms and challenging management. Hemi hang-back procedure is should be considered in difficult case.
COMPARISON OF ONH, MACULA STRUCTURE AND HFA PATTERN IN HIGH MYOPIA AND EMETROPIA EYES WITH/WITHOUT GLAUCOMA
Authors: Widhasari Idhayu anggit , Purnomo Krisna dwi , Gani Tatang Talka , Ekantini Retno
Published: January 2024

Introduction: Axial length elongation contributes a challenge in myopia eyes due to morphological and visual field abnormalities. OCT instruments do not embed a normative database from high myopia. The study is aimed to compare Cirrus OCT and HFA parameters on high myopia and emetropia with/without glaucoma.
Methods: This cross-sectional, prospective study was conducted at Sardjito General Hospital from 1st April 2021 to 11th May 2021. Patients with high myopia was enrolled with Spherical Equivalent (SE) ? -6D, 20 – 55 years of age. All participants underwent a complete ophthalmologic examination. Inclusion criteria: BCVA 20/40 or better, reliable visual field results.
Result: From 22 eyes, there were no significant difference of age between high myopia with glaucoma/HMG (n=5), high myopia/HM (n=6), emetropia with glaucoma/EG (n=5), emetropia/E (n=6) with mean age was 36±3.2 y.o and 60% were male with SE -8.5±1.03D. Among ONH parameters, there were no differences between groups. In HMG, HM, EG, E group, median avgRNFL was 85um, 96.5um, 105um, 110um respectively. Thus, median vertical CD is 0.48, 0.40, 0.58, 0.55 in HMG, HM, EG, E group respectively. Whilst median GCIPL and visual index were 75um, 78.5um, 85um, 89.5um in HMG, HM, EG, E group respectively and had significantly different 0.012 (p<0.05) between groups. Median visual field index was 92%, 97%, 98% in HMG, HM, EG group respectively with significantly different 0.04 (p<0.05).
Conclusion: The GCIPL and visual field index are significantly different between high myopia and emetropia with/without glaucoma
VISUAL OUTCOMES AND COMPLICATIONS OF IRIS-CLAW INTRAOCULAR LENS IMPLANTATION IN APHAKIC EYES WITH INADEQUATE CAPSULAR SUPPORT
Authors: Fauzi Faiz Nurboston , Dharmawidiarini Dini , Moenir Farida , Napitupulu Sahata PH
Published: January 2024

Introduction: Aphakia with inadequate capsular support remains a challenge for ophthalmologist. Although there is no consensus on the best method for this case, many studies have been reported using iris claw intraocular lens for secondary implantation.
Objective: To evaluate the various indications, visual outcomes, and complications of iris claw intraocular lens in aphakic eyes.
Methods : This retrospective case study was conducted in Undaan Eye Hospital, Surabaya, collecting data from medical records with a total of 188 eyes of 186 patients between May 2017 and April 2020, that were rehabilitated with prepupillary and retropupillary fixation of an iris claw lens. Patients were followed-up to 9 months for visual acuity and complications.
Results: The most common cause of aphakia was subluxation of lens (spontaneous, trauma or congenital) in 90 of the 188 eyes (47.3%). The mean follow-up was 3 months (range :1-9 month). Most patient had the best preoperative BCVA (0-0.50 logMAR) 63%, ranging 0-2.47 logMAR with a mean of 0.72 logMAR. At final follow up, of the total patients, 72.9 % had the BCVA of 0-0.5 logMAR, with a mean of 0.37 logMAR. Complication included secondary glaucoma 2.12%, uveitis 1.06 %, iridodyalisis 1.06 %, and bullous keratopathy 1.06%.
Conclusion: iris claw IOL implantation is a safe and effective method of rehabilitating aphakic eye with inadequate capsular support.
EFFECTS OF CATARACT SURGERY ON THE CORNEAL ENDOTHEL
Authors: Purnomo Agustian Firmansyah , Sujuti Hidayat
Published: January 2024

Introduction: Manual cataract surgery techniques such as SICS and ECCE are still used today but not as many as phacoemulsification. Corneal endothelium can be damaged due to various factors during surgery such as intraoperative manuver, excessive ultrasound power, pressure during irrigation, collision between lens fragments and corneal endothelium, large air bubbles, and increased temperature during surgery.
Methods: Journal articles and books in this paper were searched through various available search engines, including using searches through the sites Google Scholar, Medline, Proquest. The search method uses one or a combination of keywords, namely cataract surgery, corneal endothelial damage, corneal endothelium, specular microscope. Articles in this paper are found in English and Indonesian.
Results: From several studies it can be concluded that the risk factors that greatly affect the corneal endothelium include age, race, use of contact lenses, surgery, trauma, refractive errors and anatomical abnormalities on the surface of the eyeball.
Conclusion: Cataract surgery technique is significantly associated with the incidence of bullous keratopathy because the maneuvers are very prone to injuring the corneal endothel. The average percentage of damage to endothelial cells reaches 15%. This is what underlies the need for further research to find new methods that can protect the corneal endothelium.
A Teachers Guide to Outdoor Education Curriculum: Victorian Edition
Authors: Ambrosy Josh , Allen-Craig Sandy
Published: January 2024

Open Education Resource. This book provides practical advice and guidance to pre-service teachers and teachers who are teaching outdoor education in Victoria. It has been written as a handbook to support the development and delivery of school programs that align to both the Victorian Curriculum F-10 and those who deliver VCE Outdoor and Environmental Studies.
Strengthening Capacity for a Hardly Reached Pediatric Population to Achieve Equity in Access to Clinical Trials.
Authors: Opiegbe Adauge , Cutts Karen , Kelly Lewis , Tilley Elizabeth , Vasylyeva Tetyana L.
Published: January 2024

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Organisationssoziologie
Authors: Pohlmann Markus
Published: January 2024

Der Band lädt zum organisationssoziologischen Denken ein. Anhand empirischer Beispiele und Fallstudien wird in zentrale Begriffe, Konzepte und Perspektiven der Organisationssoziologie eingeführt und den Leser:innen ein ebenso fundierter wie praktischer Einstieg in deren Fragestellungen, Themen und Erklärungsformen ermöglicht.
Dabei spannt sich der inhaltliche Bogen von der Darlegung eines sozialwissenschaftlichen Verständnisses der Organisation und der Klassifizierung von Typen der Organisation über die Beschreibung zentraler Ansätze der Organisationssoziologie bis zu den Themenbereichen Motivation, Macht, Führung und Strategie. Nicht zuletzt analysiert der Autor auch Fragen der Organisationskultur und der organisationalen Kriminalität.
Das Buch bietet Studierenden sozialwissenschaftlicher und auch betriebswirtschaftlicher Studiengänge einen idealen Einstieg in dieses Thema.
Politische Medienikonografie
Authors: Grampp Sven
Published: January 2024

In diesem Lehrbuch werden Positionen der politischen Ikonografie mit medientheoretischen Ansätzen verknüpft. Ziel ist es, die Rolle der Medien für Wahrnehmbarkeit und Organisation politischer Bilder zu illustrieren. Mit zahlreichen Beispielen und Abbildungen, u.a. von Che Guevara, Willy Brandt, Barack Obama, Donald Trump und Angela Merkel sowie dem Tank Man und der Black-Lives-Matter-Bewegung.
Ein spannendes Lehrbuch für Studierende der Kultur-, Medien- und Kommunikationswissenschaft. Auch für Forschende ist das Buch ein aufschlussreiches Nachschlagewerk.
Innovationsmanagement? Frag doch einfach!
Authors: Amelingmeyer Jenny , Berger Thomas B. , Seidenstricker Sven
Published: January 2024

Dieser Band beantwortet unter anderem diese Fragen: Warum ist ein zielorientiertes Innovationsmanagement der Erfolgsfaktor für Unternehmen? Was sind die Herausforderungen des Innovationsmanagements mit Blick auf unterschiedliche Innovationsarten in Unternehmen? Welche Methoden sollten erfolgreiche Innovationsmanager:innen beherrschen? Und was sind aktuelle Trends?
Frag doch einfach! Die utb-Reihe geht zahlreichen spannenden Themen im Frage-Antwort-Stil auf den Grund. Ein Must-have für alle, die mehr wissen und verstehen wollen.
Anatomie und Physiologie der Haustiere
Authors: Gäbel Gotthold , Pfannkuche Helga
Published: January 2024

Der erfolgreiche Lehrbuchklassiker für Studierende der Agrarwissenschaften und Veterinärmedizin, aktualisiert und erweitert!
In der 16. Auflage wird verstärkt die Entwicklung von Krankheiten im Zusammenhang mit den anatomischen und physiologischen Gegebenheiten behandelt. Neben der Anatomie und Physiologie der Nutztiere einschließlich des Geflügels wird jetzt auch die des Hundes vertiefend dargelegt. Komplexe Sachverhalte werden durch Illustrationen leichter verständlich.
Aus dem Inhalt:
Zelle und Gewebe
Skelettsystem, Zähne und Skelettmuskelsystem
Blut und Infektionsabwehr
Herz, Kreislaufsystem und Gefäße
Atmungsapparat und Verdauungsapparat
Energiehaushalt und Wärmehaushalt
Harnorgane, Geschlechtsorgane und Milchdrüse
Haut und Anhangsgebilde
Nervensystem, Sinnesorgane, Endokrines System
Säure-Basen-Haushalt (neu in der 16. Auflage)
Im Anhang: Bezeichnungen, SI-Einheiten und Umrechnungen, Abkürzungen und Begriffserklärungen lateinischer und griechischer Termini.
Grundwissen Induktive Statistik
Authors: Behr Andreas , Rohwer Götz
Published: January 2024

Die Induktive Statistik bietet in der Praxis zahlreiche Anwendungsmöglichkeiten, u. a. Schätzfunktionen, Hypothesentests und Stichproben aus realen Gesamtheiten.
Auf kompakte Art und Weise stellt das Buch die Grundkenntnisse der Induktiven Statistik vor: Es vermittelt die relevanten Begriffe, Methoden und Probleme. Zudem zeigt es auf, in welchem Kontext die Induktive Statistik in den Wirtschafts- und Sozialwissenschaften Anwendung findet.
Ein Formelteil, Aufgaben mit Lösungen sowie Musterklausuren helfen dabei, das Gelernte schnell zu vertiefen.
Java Schritt für Schritt
Authors: Deininger Marcus , Kessel Thomas
Published: January 2024

Die Programmiersprache Java von Anfang bis Ende durchzuarbeiten und zu erlernen scheint für viele Studierende eine große Hürde zu sein. Nicht mit diesem Arbeitsbuch. Es führt Schritt für Schritt und leicht verständlich in die Programmiersprache ein.
Das Buch umfasst 14 Kapitel: Einführung in Java; Variablen, Datentypen, Operatoren; Kontrollstrukturen; Felder / Arrays; Methoden; Sichtbarkeit / Gültigkeit; Objektorientierte Konzepte; Ausnahmen / Exceptions; Zeichenketten / Strings; Lineare Datenstrukturen; Datenströme / Streams; Datenbanken mit Java; Graphische Benutzeroberflächen mit Swing: Einführung; komplexere Oberflächen.
Zahlreiche Übersichten und Zusammenfassungen erleichtern das Verständnis.
utb+: Begleitend zum Buch steht den Leser:innen ein E-Learning-Kurs für die Prüfungsvorbereitung zur Verfügung.
Einführung in die Psychomotorik
Authors: Fischer Klaus
Published: January 2024

Das Fach Psychomotorik hat sich zu einer anerkannten Disziplin vor allem in Pädagogik, Psychologie und Therapie entwickelt. Es ist fester Bestandteil zahlreicher Ausbildungsgänge geworden. Diese Einführung in die Psychomotorik gibt einen Überblick und erläutert Entwicklung, Schlüsselbegriffe, Theorien und Konzepte der Psychomotorik.
Arbeitsaufgaben am Ende der Kapitel helfen bei der systematischen Erarbeitung des Stoffs.
Verkehr und Tourismus
Authors: Dorsch Monique
Published: January 2024

Tourismus und Mobilität sind untrennbar miteinander verbunden. In erster Linie mag man dabei an die An- und Abreise zur Urlaubsdestination denken. Aber auch für Aktivitäten vor Ort sind Verkehrsmittel bzw. Verkehrsinfrastrukturen von entscheidender Bedeutung. Sie können sogar, z.B. bei Kreuzfahrten oder mehrtägigen Fahrradtouren, einen wesentlichen Bestandteil der Reise ausmachen oder aber, wie etwa imposante Brückenbauwerke oder Dampfbahnen, selbst als Attraktion gelten.
Zahlreiche Beispiele sowie 40 Fallstudien, die auf eigenen Erfahrungen beruhen, illustrieren die aufgegriffenen Themen und sollen beim Leser „Entdeckergeist“ wecken, um interessanten Ideen und Entwicklungen in der Realität auch selbst nachzugehen.
Grundwissen Ideenmanagement
Authors: Hentschel Claudia , Mühlemeyer Peter , Thom Norbert
Published: January 2024

Ideen allein sind – fast nichts. Erst ihre Umsetzung wird zeigen, ob in ihnen eine Innovation steckt. Ideen sind aber Energieträger: für menschengemachte Erfindungen, Problemlösungen und deren Zusammenwirken. Gutes Ideenmanagement beflügelt zu neuen Ideen. Betriebliches Vorschlagswesen und kontinuierliche Verbesserung bündeln deren Energie – alles im Sinne von nachhaltiger Wettbewerbsfähigkeit und Mitarbeiterentwicklung.
Dieses Buch stellt kompakt und prägnant ausgewählte Methoden systematischer Innovation im Unternehmen vor. Es flankiert diese Methoden durch Vorschlagswesen und Verbesserungsmanagement. Klassische Kreativitätstechniken fungieren dabei als Denkwerkzeug, Probleme überhaupt zu erkennen und gleichermaßen kreativ-divergent und zielgerichtet-konvergent zu lösen.
Die einzelnen Kapitel erklären die Grundlagen und umfassen Lernziele, Definitionen, Beispiele, Fragen und Lösungen.
Familienrecht in der Sozialen Arbeit
Authors: Benner Susanne
Published: January 2024

Das Familienrecht ist ein grundlegender Bestandteil in der Sozialen Arbeit. Susanne A. Benner führt in die Materie ein und vermittelt sodann ein umfassendes Verständnis für den Zusammenhang von Recht und Sozialer Arbeit. Strukturiert behandelt sie familienrechtliche Fragestellungen einschließlich des familienrechtlichen Verfahrens und bezieht dabei auch angrenzende Rechtsgebiete wie z. B. das Kinderund Jugendhilferecht ein. Fallbeispiele aus der Praxis bereichern die Theorie, darüber hinaus sorgen Fragen und Lösungshinweise für ein angeleitetes Selbststudium. Ein Stichwortverzeichnis sowie ein Glossar zur schnellen Recherche juristischer Termini runden das Werk ab – und machen es für Studierende der Sozialen Arbeit zu einer Leitlinie für den Umgang mit der Komplexität des Familienrechts im Arbeitsalltag.
Sozialer Wandel
Authors: Schrader Heiko
Published: January 2024

Sozialer Wandel ist ein zentrales Thema soziologischen Denkens. Heiko Schrader gibt einen Überblick über die Anfänge der klassischen soziologischen Theoriebildung, widmet sich aber auch verschiedenen Kritiken der etablierten westlichen Modernisierungstheorie. Dabei setzt er unter dem Aspekt der Pfadabhängigkeit von Entwicklung den Fokus auf die Spezifik der Modernisierung in postkolonialen und postsozialistischen Gesellschaften. Empirisch angereichert und didaktisch aufbereitet erweitert er das Forschungsfeld für Studierende der Soziologie und Politikwissenschaft um die Sichtweisen der außereuropäischen Welt und des globalen Südens. Die leicht zugängliche Einführung fängt so die Vielfalt der (postkolonialen) Moderne ein – und hinterfragt das Konzept des sozialen Wandels kritisch.
Basiswissen Tanz
Authors: Ellermann Ulla , Tietjens Maike , Thielbörger Flora
Published: January 2024

Tanz ist eine persönliche, individuelle, nonverbale, psycho-physische Ausdrucks-Bewegung, die eine enge Beziehung zur Musik aufweist. Um Tanz kompetent zu unterrichten, werden breite theoretische Grundkenntnisse in unterschiedlichen Themenfeldern benötigt, z.B. in Choreografie, Pädagogik, Projektarbeit, tänzerisch-musikalischen Grundlagen, Tanztraining, Bewegungslehre, Persönlichkeitsentwicklung oder Sozialpsychologie. Die Autorinnen erläutern die theoretischen Grundlagen sowohl kompakt und übersichtlich als auch durch Beispiele aus dem Tanz für angehende Tanzpädagog:innen in (Hoch-)Schulen und anderen Einrichtungen. Darüber hinaus finden durch die engen interdisziplinären Bezüge auch Interessierte aus den Bereichen Theater, Sport und Musik einschlägiges Hintergrundwissen für die pädagogische Ausbildungsarbeit vor.
Preparing A Seismic Database for Nineveh Governorate Using Modern Technologies
Authors: Hamdom Alaa N. , Thanoon Rayan G. , Qubaa Abdalrahman , Ali Sabah H.
Published: January 2024

Seismic activity has become noticeable in the areas adjacent to the seismic belt within the creeping Zagros range, a large earthquake occurred and was followed by aftershocks. This needs to update seismic data for areas near the Zagros range. This study aimed to prepare an integrated database of seismic activity for Nineveh Governorate, due to the importance of seismic information and the seismic code in the process of urban expansion and development in the governorate, as well as the importance in terms of monitoring and reducing natural disasters. This study included updating seismic information by reviewing the seismic archive and seismic data for the governorate, relying on several sources (research studies, seismic data, and earthquakes from multiple global observatories such as USGS, GFZ, and EMSC), in order to be published and distributed spatially on a basic map, and then preparing Peak ground acceleration map for the governorate.  As a final result of this study, it was found that there is an increase in seismic events in Nineveh Governorate, which are closely linked to the main fault system present in the geological map, and the seismic map of Nineveh Governorate has been
Decreased expression of IL-4 Gene and Exploring of mutable lymphotoxin alpha (TNF-β) gene in Patients with Systemic Lupus Erythematosus
Authors: Mohammad Wasnaa J. , Ibrahim Noor. A. , Obeid Shahad F.
Published: January 2024

Rapid genetic system identification characterizes the complex illness known as systemic lupus erythematosus (SLE). The classic cytokine, IL-4, is known to stimulate the Th2 route of differentiation and to effectively inhibit the Th1 response. The pathogenesis of systemic lupus erythematosus (SLE) has been linked to immunological and genetic variables. Therefore, this study aimed to characterize the gene expression of IL-4 in peripheral blood mononuclear cells (PBMC) and explore potential links between the functional Interleukin-4 gene and SLE. Additionally, lymphotoxin alpha (LTA) is a key cytokine in the pathogenesis of SLE. In SLE, cytokines have a significant role in controlling lymphocyte function.