bluuebunny/crossref_metadata_2025 huggingface dataset:
An extraordinary and universal matter state arises from ions and polar molecules in strict/quasi-1D structures, beyond solids, liquids, and gases
Authors: Zhongzheng Miao
Published: October 2024

Almost all existing one-dimensional materials belong to quasi-one-dimensional materials, beset with constraints in composition, fabrication, structural stability, and applicability. Based on the "universal dual-limit temperature control method," this paper employs molecular dynamics simulations and first-principles calculations to investigate typical systems of ions and mixed ionic-polar molecular systems. Remarkably, it uncovers a universal extraordinary state of matter featuring strictly one-dimensional and quasi-one-dimensional structures formed by ions and polar molecules, beyond solids, liquids, and gases. This discovery significantly expands our understanding of material structures in terms of elemental composition, spatial structure, dimensionality, distribution, and stability, opening up a new, unknown frontier for research at atomic and mesoscopic scales. In this realm, chloride and sodium ions intricately weave into spiral or curved ionic chain networks by individually linking up in space. These networks gracefully accommodate various types of ions in diverse ratios. When temperatures rise, polar molecules and ions spatially segregate, giving rise to ionic columns or clusters. This non-liquid state, bearing some liquid-like attributes, defies traditional solid-state physics. Its mesoscopic structure, boasting atomic precision, promises to reveal novel electrical, optical, acoustical, thermal, and mechanical phenomena, serving as a cornerstone for theoretical frameworks and experimental pathways in the preparation and study of new structures. The phenomena, concepts, methodologies, and principles presented in this paper delve into the depths of fundamental science, enriching our understanding of material structures and unlocking unprecedented possibilities in material science, nanotechnology, atomic manufacturing, and energy conversion. These findings are poised to catalyze advancements in multiple disciplines and exert a profound impact on society.
Along-strike extent of earthquakes on multi-segment reverse faults; insights from the Nevis-Cardrona Fault, Aotearoa New Zealand
Authors: Williams Jack , Stirling Mark , Langridge Robert , Niroula Govinda , Vause Ashleigh , Stewart James , Nicol Andy , Wang Ninghseng
Published: October 2024

Evaluating fault segmentation is important for our understanding of seismic hazard assessment and fault growth. However, it is still unclear what controls if reverse fault earthquakes will rupture across segment boundaries. Here, we combine fault mapping and trench data from the low slip rate (0.04-0.15 mm/yr) multi-segment Nevis-Cardrona Fault (NCF) in the South Island of Aotearoa New Zealand to assess if it has ruptured in single or multi-segment earthquakes during the late Quaternary. Two new trenches on its Nevis segment provide stratigraphic evidence for two surface rupturing earthquakes, which through Optically Stimulated Luminscence dating and OxCal modelling, are constrained to have occurred at 28.9 +12.9 -9.1 ka and 12.8 ± 4.9 ka. The most recent timing is only weakly correlated to surface rupture timings from two trenches along the NCF's NW Cardrona segment. Furthermore, the 2 ± 1 m Nevis segment single event displacements we estimate would be unusually low for a ~85 km long NCF multi-segment rupture. We therefore surmise that late Quaternary NCF surface rupturing earthquakes did not rupture through ~30-50° bends that link these segments. Our trench data and fault mapping also indicate lower slip rates on the Nevis segment than previous studies (0.04-0.1 mm/yr vs 0.4 mm/yr).
BACH1 as a key driver in rheumatoid arthritis fibroblast-like synoviocytes identified through gene network analysis
Authors: Pelissier Aurelien , Laragione Teresina , Harris Carolyn , Rodríguez Martínez María , Gulko Percio S
Published: October 2024

RNA-sequencing and differential gene expression studies have significantly advanced our understanding of pathogenic pathways underlying rheumatoid arthritis (RA). Yet, little is known about cell-specific regulatory networks and their contributions to disease. In this study, we focused on fibroblast-like synoviocytes (FLS), a cell type central to disease pathogenesis and joint damage in RA. We used a strategy that computed sample-specific gene regulatory networks to compare network properties between RA and osteoarthritis FLS. We identified 28 transcription factors (TFs) as key regulators central to the signatures of RA FLS. Six of these TFs are new and have not been previously implicated in RA through ex vivo or in vivo studies, and included BACH1, HLX, and TGIF1. Several of these TFs were found to be co-regulated, and BACH1 emerged as the most significant TF and regulator. The main BACH1 targets included those implicated in fatty acid metabolism and ferroptosis. The discovery of BACH1 was validated in experiments with RA FLS. Knockdown of BACH1 in RA FLS significantly affected the gene expression signatures, reduced cell adhesion and mobility, interfered with the formation of thick actin fibers, and prevented the polarized formation of lamellipodia, all required for the RA destructive behavior of FLS. This study establishes BACH1 as a central regulator of RA FLS phenotypes and suggests its potential as a therapeutic target to selectively modulate RA FLS.
STUDY OF TANNING SUBSTANCES AND FLAVANOIDS IN THE LEAVES OF ASIAN AGRIMONY(AGRIMONIA ASIATICA JUZ.)
Authors:   AL-FARABI KAZAKH NATIONAL UNIVERSITY, Kaliyeva Anar , Mamytova Nurgul , Medeuova Galiya , Sadykova Damezhan , Rakhimova Zaida
Published: October 2024

Asian agrimony (Agrimonia asiatica Juz) is a common wild plant including that growing within the territory of Kazakhstan, a very promising raw material for flavonoids and tanning substances release. These active substances have significant pharmacological potential. The article presents the results of work on determining the quantitative and qualitative composition of tannins and flavonoids in plant raw materials from the Asian agrimony (Agrimonia asiatica Juz). The presence of tanning substances and flavonoids in the extracts received from the above-ground part of Asian agrimony has been established by qualitative reactions. Various developers for paper chromatography have been used. The quantita-tive determination of flavonoids has been carried out in terms of the equivalent amount of quercetine, and the standard method of permanganatometric titration has been used to determine the quantitative content of tanning substances. Quantitative content of tanning substances in the leaves of Asian agri-mony (A. asiatica juz.) showed an 8,156 %, and a quantitative content of flavonoids showed 1,9 %. The purpose of the study is to determine the quantitative and qualitative composition of tannins and flavanoids in prepared herbal medicinal raw materials in order to identify the most promising objects for further research.
Perosomus acaudatus associado à atresia anal em bezerro: relato de caso
Authors: Souza Rodrigo Santos Severo de , Siqueira Henrique Ravalha e , Dallanôra Caroline Garlet , Stroeher Romário , Rech Rodrigo Dalmina , Cecim Marcelo da Silva , Fidelis Junior Otavio Luiz , Leal Marta Lizandra do Rêgo
Published: October 2024

Objetivou-se abordar o caso de um bezerro apresentando Perosomus acaudatus associado à atresia anal. Segundo o proprietário, no primeiro manejo do bezerro foi verificada ausência da cauda e ânus, sendo realizada uma perfuração na região perineal. Ao ser atendido pela Clínica de Ruminantes do Hospital Veterinário Universitário da Universidade Federal de Santa Maria (HVU-UFSM) foi confirmada ausência de cauda e ânus, com presença de uma ferida em cicatrização na região perineal e depressão longitudinal na região dorsal da pelve. Foi realizado exame radiográfico que revelou três vértebras sacrais não fusionadas e ausência de vértebras coccígeas, além de cólon e reto preenchidos por gás. Foi proposto ao proprietário a realização do tratamento cirúrgico para correção da atresia anal. Devido a aderências do reto na região pélvica, não foi possível realizar a anoplastia, mas sim a colostomia na parede abdominal, na região inguinal esquerda. Após o procedimento o paciente conseguiu defecar, porém, na semana seguinte este apresentou apatia e prostração. Uma amostra de líquido peritoneal foi coletada, sendo verificada alteração de coloração e turbidez e aumento de células nucleadas. Diante dos achados foi realizada eutanásia e necropsia do animal, sendo observada a ausência de vértebras coccígeas, presença de apenas três vértebras sacrais, peritonite fibrinonecrossupurativa difusa, colite necrosante difusa transmural e dermatite necrosante multifocal. A ocorrência de Perosomus acaudatus, apesar de rara, deve sempre ser examinada de perto, a fim de identificar possíveis outras alterações associadas. O desfecho deste paciente não muda a indicação de correção cirúrgica para os casos de atresia anal.
Hiperplasia epitelial nodular no cólon de um gato associada a Strongyloides sp.: relato de caso
Authors: Rodrigues Vitoria de Cássia Coelho , Abreu Douglas Marinho , Baêta Silvia de Araújo França , Evangelista Luanna Soares de Melo , Cruz Maria do Socorro Pires e
Published: October 2024

Objetivou-se, com o presente relato, descrever um caso de colite hiperplásica associada ao parasitismo por Strongyloides sp. em um gato macho de dois anos de idade, atendido na emergência apresentando tenesmo e prolapso retal. Foi realizada uma laparotomia exploratória em que foi possível observar nódulos transmurais no ceco e cólon, com diâmetro variando entre 2 e 4mm, de distribuição multifocal a coalescente, consistência firme e que, ao corte, continham sangue. Histologicamente, os nódulos eram áreas circulares compostas por projeções da mucosa intestinal para a submucosa, formadas por estruturas tubulares revestidas por uma camada de enterócitos volumosos monomórficos e raras células caliciformes. Larvas rabditoides, filarioides e adultos com morfologias compatíveis com nematoides do gênero Strongyloides foram observados no lume do epitélio hiperplásico, entre os túbulos e no limite dos nódulos, possivelmente constituindo a causa primária dessas alterações no animal.
Compactação gastrointestinal em uma tartaruga-verde (Chelonia mydas) juvenil por ingestão de resíduos sólidos: relato de caso
Authors: Marques Robert Danyllo Pereira , Bezerra Taciana Cássia Santos , Fossá Maria Vitória de Alencastro , Araujo Igor Oliveira de
Published: October 2024

A ação da humanidade tem causado sérios prejuízos à vida marinha. Dentre as espécies mais afetadas pela presença de resíduos sólidos no mar, as tartarugas destacam-se por frequentemente ingerir os resíduos. Como consequência, o animal pode apresentar obstrução do trato gastrointestinal e evoluir para óbito. Objetivou-se relatar a compactação gastrointestinal em uma tartaruga-verde (Chelonia mydas) juvenil por ingestão de resíduos sólidos. O animal foi encontrado encalhado no litoral pernambucano e encaminhado para reabilitação. Ao exame clínico inicial, apresentava-se caquético, apático, com cracas e algas aderidas ao corpo, fraturas na carapaça e exposição óssea em plastrão. O paciente foi tratado por oito dias, porém veio a óbito. Na necropsia, foram constatadas alterações como úlcera de córnea no olho direito; líquido amarelo-esverdeado livre na cavidade celomática; hematoma abaixo de placas do casco e costelas; coração pálido e friável; rim direito com áreas hemorrágicas e tamanho reduzido em relação ao esquerdo; musculatura peitoral friável; lobo direito do fígado apresentando áreas esbranquiçadas e aumento de bordos; sinais de pneumonia, como muco em traqueia, brônquios e em pulmão esquerdo. No trato gastrointestinal, foi encontrado conteúdo alimentar e resíduos sólidos como plásticos e fibra sintética, além de vasos mesentéricos ingurgitados, fecaloma e úlceras em mucosa. A conclusão do caso foi morte por compactação em trato gastrointestinal, causada por presença de resíduo sólido e possível processo séptico.
Enhancing Biometric Security with Bimodal Deep Learning and Feature-level Fusion of Facial and Voice Data
Authors: Merit Khaled , Beladgham Mohammed
Published: October 2024

Recent research in biometric technologies underscores the benefits of multimodal systems that use multiple traits to enhance security by complicating the replication of samples from genuine users. To address this, we present a bimodal deep learning network (BDLN or BNet) that integrates facial and voice modalities. Voice features are extracted using the SincNet architecture, and facial image features are obtained from convolutional layers. Proposed network fuses these feature vectors using either averaging or concatenation methods. A dense connected layer then processes the combined vector to produce a dual-modal vector that encapsulates distinctive user features. This dual-modal vector, processed through a softmax activation function and another dense connected layer, is used for identification. The presented system achieved an identification accuracy of 99% and a low equal error rate (EER) of 0.13% for verification. These results, derived from the VidTimit and BIOMEX-DB datasets, highlight the effectiveness of the proposed bimodal approach in improving biometric security.
Therapeutic potential of phytocompounds of Bacopa monnieri (L.) Wettst (literature review)
Authors: Nikitina O.O. , Tsyba D.S.
Published: October 2024

The aim of the work was to evaluate the pharmacological effects and therapeutic potential of individual compounds and extracts of B. monnieri based on the analysis of data from scientific periodicals regarding chemical composition and biological action. Theoretically significant were the studies of the materials of the scientific-metric database PubMed and Google Scholar over the last five years regarding the chemical composition and biological action of extracts based on B. monnieri and their individual components. The search query was carried out by the Latin name of the plant, with the exception of publications related to botanical research. In separate PubChem searches, names of individual phytocompounds were used to establish structure and distribution in plants. The SuperPred web server was used to predict therapeutic potential. The authors analyzed the chemical composition of the extracts, presented the structural and pharmacological characteristics of bacosides and their aglycones: bacosin and juubogenin, cucurbitacin E, loliolide, betulinic and asiatic acids and the flavonoid oroxindin. The mechanism of action of bacoside on β-amyloid is characterized and illustrated. Using machine learning, the prospects for using the main compounds of bacopa to create drugs were calculated taking into account the ATC classification, their biological effects and alternative plant sources were given. Experimental animal studies of whole aqueous or ethanolic extracts of B. monnieri have been found to support a cognitive enhancement effect. The extract was not toxic to humans. Numerous clinical trials show the effectiveness of the use of extracts in the treatment of anhedonia, depression, Alzheimer's disease, Parkinson's disease, dementia and hyperactivity. An analysis of clinical studies in Ukraine shows that drugs based on B. monnieri can be used in the complex treatment of cognitive impairment associated with dyscirculatory encephalopathy in adults and perinatal CNS damage in children. Considering the amphiphilicity of bacosides and the non-toxicity of extracts, they can be involved in the development of various dosage forms with a wide range of therapeutic applications. Further study of the pharmacological action of B. monnieri and the development of drug technology for solid and liquid dosage forms based on it are promising.
Clinical course of atrial fibrillation in patients who experienced coronavirus disease (COVID-19): results of a 6-month follow-up
Authors: Sychov O.S. , Stasyshena O.V.
Published: October 2024

Atrial fibrillation (AF) is the most common extrapulmonary complication of the past SARS-CoV-2 infection. According to experts, almost 20% of patients with past COVID-19 have a history of atrial fibrillation and the incidence of new paroxysms of this arrhythmia ranges from 10 to 18%. Referring to the studied patients who experienced COVID-19 more than 6 months ago, the subjective perception of cardiac arrhythmia is the most frequent complaint, reported by approximately two-thirds of patients. The aim of our study was to determine the course of atrial fibrillation in patients after past 2019 coronavirus disease (COVID-19) during a dynamic 6-month follow-up after the initial hospitalization for atrial fibrillation in the specialized department of cardiac arrhythmias of the SI “National Scientific Center” “M.D. Strazhesko Institute of cardiology, clinical and regenerative medicine of the National Academy of Medical Sciences of Ukraine” depending on the clinical and anamnestic, demo­graphic, anthropometric factors, the results of laboratory research methods and the received treatment. 36 patients were included in the study, 27 of them formed the first group, which included patients in whom the course of atrial fibrillation improved against the background of recommended antiarrhythmic treatment after initial hospitalization for AF and past COVID-19, who at the time of hospitalization had a negative PCR test, of which 17 were women and 10 were men, aged 62.38±1.83 years. The second group consisted of 9 patients including 4 women and 5 men, aged 69.88±2.60 years in whom the course of atrial fibrillation neither changed nor worsened. We determined that the number of patients in whom the course of atrial fibrillation improved during the 6-month follow-up was three times greater than those in whom the course of this arrhythmia neither changed nor worsened (75% and 25%, respectively). Patients with a more favorable course of atrial fibrillation were younger (on average by 7.5 years), three times less likely to suffer from diabetes and not often had arterial hypertension of the III stage, than those examined, in whom the course of this arrhythmia did not change or worsen. Systemic inflammation and severity of heart failure significantly worsen the course of AF within 6 months after the hospital stage of treatment. However signs of deterioration of lipid metabolism are characteristic of patients with an unfavorable course of atrial fibrillation during 6 months after hospitalization, which is probably caused by the activation of systemic inflammation in them. The improvement of the prognosis of the examined patients was probably influenced by the appointment of antiarrhythmic drugs, such as: amiodarone, flecainide, beta-blockers, statins – from the "up-stream" therapy drugs.
Respiratory disease detection in lung auscultation with convolutional neural networks and CVAE augmentation
Authors: Panaskin D.V. , Stirenko S.H. , Babko D.S.
Published: October 2024

The main purpose of this work was to investigate the possibility of detecting respiratory diseases in audio recordings of lung auscultation using modern deep learning tools, as well as to explore the possibility of using data augmentation by generating synthetic spectral representations of audio samples. The ICBHI (International Conference on Biomedical and Health Informatics) dataset was used for training, validation and augmentation. The dataset includes lung auscultations of 126 different subjects, there are a total of 920 sounds, of which 810 have signs of chronic diseases, 75 of non-chronic diseases and 35 with no pathology. The stage of data preprocessing includes discretization to 4kHz frequency, as well as filtering of frequency bands that do not carry information value for the task. In the next step, each sample was transformed into a frequency spectrum and Melspectrograms were generated. To solve the problem of class imbalance, the required number of synthetic spectrograms generated by convolutional variation autoencoders was added. At the stage of building the model, the methods of classical convolutional neural networks were used. The quality of the obtained algorithm was evaluated using a 10-fold cross-validation. Also, to assess the generalization of the proposed method, experiments were performed with the split of audio recordings into training and test sets using patient grouping. Qualitative evaluation of the model was performed using sensitivity, specificity, F1-score and Cohen’s kappa. A score of 98.45% F1-score was achieved for the 5-class classification problem which can contribute to the development of ways to synthesize and augment sensitive medical data. In addition, a cons of existing methods in the generalization of the obtained predictions were revealed, which opens the way for further research in the direction of clinical respiratory diseases detection.
Oral microbiocenosis state under different approaches of replacing dental crown defects
Authors: Sardykov Ye.A. , Ishchenko O.V. , Fastovets O.O.
Published: October 2024

Dental caries is one of the most common health problems. The aim of the research was to study the spectrum of microbiota, which is part of the dental biofilm, and its biological properties. The study involved 90 participants of the study group and 20 of the control group. Dental plaque and saliva were used as principal clinical specimens. The main research method was bacteriological. All samples from study participants were positive for microbiota. At the initial collection of material, 395 unique isolates were obtained: 338 from patients with caries and 57 from healthy volunteers. The microbiocenosis of the oral cavity associated with the development of caries contained such eudodominants as Streptococcus mutans, Peptostreptococcus spp., Fusobacterium spp., Prevotella spp. and dominants Streptococcus pyogenes, Enterobacterales, Prevotella spp. and Candida albicans. In contrast the eudominants of the healthy oral cavity were microorganisms with known commensal properties, in particular Streptococcus salivarius, Aerococcus viridans, Veillonella spp. After the dental treatment, significant shifts in the taxonomic composition of the dental biofilm were observed. Therefore, the composition of the oral cavity microbiocenosis in participants who underwent restoration of the dental crown defects with zirconium inserts approached patients to the healthy cohort participants. The eudodominants of the oral microbiocenosis of the participants who underwent direct restoration were S. mitis, Peptostreptococcus spp. and Veillonella spp. In zirconium restoration, the commensals S. salivarius and A. viridans were eudodominants. The obtained isolates of opportunists possessed high virulence properties. Streptococcus spp. cultures were sensitive to norfloxacin screening in only 28.6% of cases. Among cultures of the genus Staphylococcus, 23.8% were methicillin resistant. Representatives of Enterobacterales had chemotherapeutic sensitivity that varied significantly depending on the group of antimicrobial agents. Using disks with phenylboronic acid, ethylenediaminetetraacetic acid and cloxacillin, it was established that Klebsiella spp. were producers of class A carbapenemases (n=3) and contained AmpC (n=3). Carbapenemases were also produced by at least 65.2% of the studied cultures of non-fermenting gram-negative microorganisms. In our study, all obtained isolates were also endowed with the ability to form a biofilm. Therefore, microbiological research in dentistry should be considered as one of the objective methods for assessment of health of the oral cavity and will also have advantages in choosing a method of correcting defects of dental crown parts and in some cases, making an informed decision about the prescription of antimicrobial treatment.
ТЕНДЕНЦИИ РАЗВИТИЯ ТРАНСПОРТНЫХ ПОТОКОВ И ЛОГИСТИЧЕСКИХ ПРОЦЕССОВ В РЕГИОНЕ
Authors: НАБИЕВ РАМАЗАН АБДУЛМУМИНОВИЧ , БАТМАНОВ ЭДВАРД ЗАГИДИНОВИЧ , ЛУНЕВА ТАТЬЯНА ВИКТОРОВНА
Published: October 2024

В статье раскрыты ключевые аспекты структуры транспортных потоков и логистических процессов в Республике Дагестан, включая модальное распределение транспортной сети и пространственную структуру перевозок. Также изучены основные направления развития транспортно-логистического комплекса региона, такие как создание портовой особой экономической зоны, модернизация системы морского транспорта, развитие железнодорожного, автомобильного и авиационного транспорта. В статье рассмотрены перспективы интеграции всех участников логистических процессов в единую цепь поставок и создание многоуровневой логистической системы. Цель статьи заключается в выявлении основных закономерностей и тенденций, управляющих движением товаров и пассажиров внутри региона, а также в определении стратегических направлений развития транспортной инфраструктуры до 2030 года. Практической значимостью обладают выводы о необходимости формирования единой транспортно-логистической системы региона и рекомендации по улучшению управления транспортными потоками. Ожидаемые результаты включают повышение эффективности транспортной системы, улучшение экономической интеграции региона и развитие сопряженных отраслей экономики. В заключении подчеркивается важность согласованного подхода к развитию транспортной инфраструктуры для обеспечения устойчивого экономического роста Республики Дагестан.
МОДЕЛЬ И МЕХАНИЗМ РАЗВИТИЯ ИНТЕГРАЦИОННЫХ ПРОЦЕССОВ И УКРЕПЛЕНИЯ КООПЕРАЦИОННЫХ СВЯЗЕЙ МЕЖДУ РД И НОВЫМИ РЕГИОНАМИ РФ В УСЛОВИЯХ СОВРЕМЕННЫХ ВЫЗОВОВ
Authors: МЕДЖИДОВ ЗАУР УРУДЖАЛИЕВИЧ
Published: October 2024

Цель исследования. Разработать научно-практические рекомендации по развитию интеграционных процессов и укреплению кооперационных связей между РД и новыми регионами России в условиях современных вызовов. Методология исследования основана на использовании методов сравнительного и факторного анализа, синтеза, систематизации, обобщения, аналогии. Результаты. Определены основные признаки и последствия межрегиональной интеграции, разработана модель развития интеграционных процессов и взаимодействия участников кластерных форм кооперации предприятий Республики Дагестан и новых регионов России, разработан механизм развития традиционной региональной интеграции и частно-корпоративной интеграции предприятий Республики Дагестан с регионами Донбасса и Новороссии. Выводы. Обозначены основные преимущества сотрудничества между Республикой Дагестан и новыми регионами России.
УПРАВЛЕНИЕ УСТОЙЧИВЫМ РАЗВИТИЕМ ГОРОДОВ РОССИИ
Authors: БЕРМАН СВЕТЛАНА СЕРГЕЕВНА , КЛИМОВ АЛЕКСАНДР АЛЕКСАНДРОВИЧ
Published: October 2024

В данной статье рассматривается концепция «умных устойчивых городов», возникающая на пересечении устойчивого развития, урбанизации и информационно-коммуникационных технологий (ИКТ). Основной объект исследования – крупные российские города, лидеры ESG-рейтинга ИНФРАГРИН 2023: Ижевск, Иркутск, Кемерово, Рязань, Севастополь, Ставрополь, Тюмень и Хабаровск. Целью исследования является разработка практических рекомендаций по совершенствованию управления устойчивым развитием городов России на основе анализа текущих проблем и возможностей. Исследование включает ряд задач: анализ существующих методик оценки управления устойчивым развитием территории и разработка авторской методики, панельный анализ факторов качества жизни, сравнительный анализ динамики индексов устойчивого развития и разработка рекомендаций. Методология исследования базируется на последовательном применении панельного анализа влияния факторов качества жизни на индекс устойчивого развития и использовании метода анализа иерархий (МАИ). В качестве информационной базы использованы нормативно-правовые акты, стратегические документы, отечественные и зарубежные публикации, статистические данные и аналитические материалы. Основные результаты исследования показали, что качество жизни населения, доходы и оценка работы городских властей оказывают значительное влияние на устойчивое развитие городов. Модель панельного анализа с фиксированными эффектами и модель со случайными эффектами продемонстрировали высокую точность прогнозов, что подтверждает эффективность выбранных методик. Практическая значимость работы заключается в разработке рекомендаций для муниципальных органов власти, направленных на повышение качества жизни и устойчивого развития городов. Перспективы исследования включают дальнейшую интеграцию ИКТ в управление устойчивым развитием городских процессов и разработку единых подходов устойчивого развития на муниципальном уровне.
ПРОБЛЕМЫ И ВЫЗОВЫ ТРАНСПОРТНОГО КОМПЛЕКСА РЕГИОНА: СОСТОЯНИЕ ИНФРАСТРУКТУРЫ И ТРАНСПОРТНЫХ СЕТЕЙ
Authors: БАТМАНОВ ЭДВАРД ЗАГИДИНОВИЧ , ИБРАГИМОВА ПАИЗАТ АЛИЕВНА , БАТМАНОВА КАМИЛЛА МАРАТОВНА
Published: October 2024

В статье раскрыты проблемы и вызовы транспортного комплекса Республики Дагестан, а также текущее состояние и перспективы его развития. Также изучены ключевые аспекты функционирования различных видов транспорта, включая железнодорожный, автомобильный, морской и воздушный, а также их взаимодействие между собой. В статье рассмотрены вопросы модернизации инфраструктуры, финансирования и управления транспортными сетями в контексте роста туристического потока и географических особенностей региона. Цель статьи заключается в анализе состояния транспортного комплекса, выявлении существующих проблем и предложении возможных путей их решения. Практической значимостью обладают рекомендации по улучшению качества транспортной инфраструктуры, оптимизации логистических процессов и увеличению эффективности транспортных услуг. Ожидаемые результаты включают разработку комплексных стратегий для модернизации транспортных сетей, улучшение координации между различными видами транспорта и повышение общей устойчивости транспортного комплекса Республики Дагестан. В заключении подчеркивается необходимость системного подхода к решению выявленных проблем и внедрения инновационных решений для обеспечения устойчивого развития транспортной инфраструктуры региона.
ЧАСТНЫЕ КЛИНИКИ В СИСТЕМЕ ОМС: ДОСТИЖЕНИЯ, ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ РАЗВИТИЯ
Authors: ФИЛИНА МАРИНА АЛИЯРОВНА , ОРУДЖЕВА САИДА АЛИЯРОВНА
Published: October 2024

Статья посвящена исследованию проблем, препятствующих широкой интеграции частных медицинских организаций в систему обязательного медицинского страхования. Описана современная динамика изменения их численности и выявлены факторы, ее определяющие. Обоснована важная роль коммерческих клиник как особых, социально ориентированных рыночных институтов, создающих необходимые конкурентные отношения в отрасли, повышающих доступность и качество медуслуг, расширяющих право пациентов на выбор медицинских организаций. В результате проведенного анализа сделан вывод о том, что основным препятствием для широкого вовлечения частных клиник в систему государственного социального страхования является слабое актуарное обоснование тарифов на амбулаторную и стационарную помощь, а также отсутствие методики планирования объемов медпомощи для всех учреждений, вне зависимости от формы собственности, на конкурсной основе с учетом объективных качественных критериев оценки услуг, оказываемых медицинской организацией. Выявленные в данном исследовании проблемы предопределяют направления дальнейшей активизации частного бизнеса в системе государственного медстрахования. Информационную базу исследования составили нормативные правовые акты и научные труды отечественных авторов, посвященные порядку финансирования учреждений здравоохранения в России. В работе применены такие общенаучные методы, как наблюдение, сравнение, анализ, систематизация и ряд других.
СТРУКТУРА МЕХАНИЗМА И ЗАРУБЕЖНЫЙ ОПЫТ ПОСТРОЕНИЯ СИСТЕМЫ ФИНАНСИРОВАНИЯ ИННОВАЦИОННОГО РАЗВИТИЯ НАЦИОНАЛЬНОЙ ЭКОНОМИКИ
Authors: ЗОИДОВ КОБИЛЖОН ХОДЖИЕВИЧ , РАСТЕГАЕВ АНДРЕЙ АЛЕКСАНДРОВИЧ
Published: October 2024

Цель работы. В статье рассматривается структура механизма инновационного развития и зарубежный опыт построения системы финансирования инновационного развития национальной экономики. Методология. В исследовании использованы методы историко-экономического анализа, теории производственно-технологической сбалансированности экономики, системной парадигмы, эволюционно-институциональной теории, экспертных и аналитических оценок. Результаты. Сформулирована структура механизма инновационного развития национальной экономики. Эта структура включает в себя несколько ключевых элементов: научно-исследовательские институты и университеты, технологические парки и бизнес-инкубаторы, финансовые инструменты, такие как венчурное финансирование и государственные гранты, а также законодательную базу, регулирующую интеллектуальную собственность и стандарты. Сформулирован международный опыт построения системы финансирования инновационного развития. Основное внимание уделено модели тройной спирали, которая расширяется и адаптируется с участием дополнительных акторов, формируя четвертую или пятую спирали в некоторых странах. Выводы. Разработка и реализация инновационной политики направлена на поддержку исследований и разработок, коммерциализацию технологий и создание благоприятной инновационной инфраструктуры, что является основой для достижения устойчивого экономического роста. Модель тройной спирали включает систематическое вовлечение государства, научных учреждений, бизнеса и граждан в инновационный процесс, что приводит к разработке и коммерциализации инновационных продуктов и технологий.
Understanding the Republic of Malawi’s trade dynamics: A Bayesian gravity model approach
Authors: Sambiri B. B. , Mutai N. C. , Kumari S.
Published: October 2024

International trade enables countries to expand their markets, access more products, improve resource allocation, and boost economic growth by leveraging comparative advantage and specialization. The aim of this article is to analyze the primary factors that influence Malawi’s international trade flows. The study is relevant because it examines Malawi’s trade patterns with its main partners, which include surrounding nations and traditional trade allies. The novelty is that, through the analysis, the research offers valuable insights into the primary factors that influence Malawi’s international commerce. Panel data is gathered from various sources, including the International Monetary Fund (IMF) and World Bank, covering the period from 2000 to 2023 for 11 countries that are trading partners with Malawi. We employ the Bayesian Mindsponge gravity methodology. The results show that the economic size (characterized by the gross domestic product) of the origin and destination countries, bilateral agreements, and the population size of the destination country have a beneficial impact on Malawi’s exports. In conclusion, Malawi’s export performance is significantly enhanced by the economic size of both Malawi and its trading partners, the existence of bilateral agreements, and the population size of the destination countries, underscoring the importance of strategic economic partnerships and targeted trade policies in boosting Malawi’s international trade. We recommend Malawi authorities focus on strengthening bilateral agreements and targeting trade relationships with larger and more populous economies to boost international trade.
Integrating Factor Models Using Bayesian Model Averaging: Evidence from Korea
Authors: Ban Youjeong , Jang Jeewon
Published: October 2024

This study applies the Bayesian model averaging approach to the Korean stock market data to yield an integrated factor model that can address model uncertainty. During the period from 2004 to 2022, we choose 14 factors and 10 macro predictors and generate a total of 10,485,760 candidate factor models by considering all possible combinations of each variable and whether to allow for model mispricing. The integrated model estimates the expected return and covariance matrix by combining the predictions of all the candidate models using Bayesian posterior probabilities as weights. In the Korean stock market, there is no clear winner model with dominant posterior probabilities, implying that model uncertainty is substantial. The optimal portfolio of the integrated model has a higher out-of-sample Sharpe ratio and lower downside risk than benchmark factor models. Model uncertainty has a significant impact on the estimation of the covariance matrix of the integrated model, and model disagreement about expected returns is particularly acute during periods of sharp market declines. In the presence of model uncertainty, Bayesian investors perceive equities to be riskier than historical volatility.
El-Ahtal ve Cerîr’in Emevî Halifelerine Methiyeleri: Siyasi Şiir
Authors: Tuna Sedat
Published: October 2024

Dünya sahnesinde insanlar yer almaya başladığından itibaren her zaman diliminde insanları babadan oğula geçen bir yönetim anlayışıyla ya da seçimle iş başına gelerek yönetmeye ve insanlar üzerinde hâkimiyet kurmaya çalışan yöneticiler her daim var ola gelmiştir. Siyasi otoritelerin yaptıkları uygulamalardan memnun olan bir kitle olduğu gibi memnun olmayan muhalif bir kitlede her daim olmuştur. Yönetimi destekleyen kitleler yaşadıkları dönemin şartlarına göre yöneticilere methiyeler düzüp onları desteklerken desteklerinin karşılığını ödül olarak almışlardır. Muhalif gruplar da yönetime karşı eleştirilerini yüksek sesle dillendirmişler ve yaptıkları muhalefetin karşılığını da yöneticiler tarafından iktidarın nimetlerinden mahrum bırakılmak suretiyle almışlardır. Emevî halifelerinin yanlış uygulamaları sonucunda halk arasında ayrışmalar ve gruplaşmalar meydana gelmiştir. Ayrışan bu gruplar kendilerini en iyi şekilde ifade etmenin ve kendi görüşlerini halka aktarmanın yolunu o dönemin medyası kabul edilen şiir de bulmuşlardır. Şairin inşâd edip dillendirdiği şiir sanki o dönemde olup bitenlerin bir yansıması gibidir. Emevîler Dönemi’nde Arap şiiri biçimsel özelliğini korumuştur. Ancak Câhiliye Dönemi’nde var olan medih, hiciv, gazel, risâ, hamriyyât, fahr gibi şiir çeşitlerinin yanı sıra yeni bir tür olmakla beraber kökleri geçmişe uzanan siyasi şiir olgusu da ortaya çıkmıştır. Emevîler’in iktidarda olduğu dönemde medya görevini o dönemin en önemli aktörleri kabul edilen şairler yerine getirmişlerdir. Yönetimi destekleyen şairler günümüzün ifadesiyle yandaş medya muhalifler ise muhalif medya olarak isimlendirilmiştir. Emevî Dönemi’nde halifeleri destekleyen ve destekleriyle ses getiren iki önemli şair el-Ahtal ve Cerîr’dir. Emevî Döneminin bu iki önemli şairi adeta halifelerin profesyonel meddahları olmuşlardır. Bu çalışmada bu iki önemli profesyonel meddah şairin sadece halifeler için inşâd ettiği methiyelere yer verilerek o dönemde şairin ve şiirin toplumdaki etkisine vurgu yapılacaktır.
Wilhelm Dilthey’in Felsefi Projesi Üzerine Bir İnceleme
Authors: Karaca Aziz Murat , Topakkaya Arslan
Published: October 2024

Bu çalışma, Dilthey’in, tin bilimlerinin temellendirilmesi açısından oluşturmaya çalıştığı felsefi projesini konu edinmektedir. Temel problemimiz, Dilthey’in felsefi projesinin açığa çıkma koşullarının ve bu projenin genel hatlarının ne olduğu üzerinedir. Dilthey, döneminin önemli tartışmalarından birisi olan, doğa ve insan bilimleri arasında ne gibi farkların olduğuna yönelik tartışmayı ele alıp, kendisinin tin bilimleri olarak adlandıracağı insan bilimleri için metodolojik açıdan bir temellendirme vermek ister. Çünkü o dönemde insan bilimleri, doğa bilimlerinin etkisinde kalmış ve ağırlıklı olarak doğa bilimlerinin yöntemini kullanmıştır. Dilthey, bu tutumun yanlış olduğunu düşünerek doğa bilimlerinin etkili olan paradigmalarının, insan ve insanın içerisinde yer aldığı toplumu anlamlandırmakta nasıl yetersiz kaldığını çözümlemek istemektedir. Nitekim, eğer tin bilimleri, bağımsız bir alan olacaksa ve aynı zamanda nesnel ölçekte sonuçlar verecekse kendisine ait yapısal çerçevesinin olması gerektiğini düşünmektedir. Bunun sonucunda ise insan bilimlerine yönelik kendi modelini temellendirmek istemektedir. Bu temellendirmede, kendisinden sonraki felsefeyi etkileyebilecek önemli fikirleri öne çıkmıştır. Tarihsellik ve hermeneutik bu fikirlerdendir. İnsanın tarihsel bir varlık olduğunu vurgulaması bakımından tarihsellik fikrini ön plana çıkarmıştır. Benzer biçimde, insanın bütünselliğini idrak etmenin anlamlandırma ile mümkün olduğunu ve bu anlamlandırmanın da hermeneutik ile sağlandığı ifade ederek hermeneutik fikrini vurgulamıştır. Fakat her iki kavramı da geleneksel anlamlarından farklı olarak, amaçladığı proje kapsamında felsefi bağlamda ele almıştır. Bu çalışma, Dilthey’in bu projesini genel çerçevesiyle ortaya koymayı amaçlamaktadır.
Şükür, Kaygı ve Psikolojik İyi Hal Arasındaki İlişkiler Üzerine Deneysel Bir Çalışma: Şükür Eğitimi
Authors: Karaca Faruk , Acuner Hacı Yusuf , Dilek Yunus , Atabay Muharrem
Published: October 2024

Bu çalışmada ortaöğretim öğrencilerine yönelik sahip olunan nimetler temalı farkındalık eğitimi aracılığıyla öğrencilerin şükür düzeylerinin artırılması amaçlanmıştır. Ayrıca şükür duygusu ile sürekli, durumluk kaygısı ve psikolojik iyi oluş arasındaki ilişkinin araştırılması hedeflenmiştir. Çalışmada ön test son test ölçümlü deney ve kontrol gruplu desende deneysel araştırma yöntemi tercih edilmiştir. Çalışmanın örneklemi tipik durum örneklemesi yöntemiyle belirlenmiştir. Artvin ilindeki bir ortaöğretim kurumunda öğrenim gören öğrenciler çalışmanın örneklemini oluşturmaktadır. Çalışmada veri toplama aracı olarak Göcen tarafından Türkçeye uyarlaması yapılan “Şükür Ölçeği”, Demirci ve Ekşi tarafından Türkçeye uyarlaması yapılan “EPOCH Ölçeği” ve Öner ve Le Compte tarafından Türkçe uyarlaması yapılan “Durumluk ve Sürekli Kaygı Ölçeği” kullanılmıştır. Her ders bir etkinlik olmak üzere haftalık 2 dersten toplamda 4 hafta 8 ders sürecek olan farkındalık eğitimi hazırlanmış ve deney grubuna uygulanmıştır. Çalışmanın bulgularına göre farkındalık eğitimine katılan öğrencilerin şükür düzeylerinde son test puanlarında ön test puanlarına göre anlamlı düzeyde artış olduğu görülmektedir. Ön test verilerine göre şükür ile sürekli, durumluk kaygısı arasında negatif yönde, psikolojik iyi oluş ile pozitif yönde anlamlı ilişki olduğu görülmektedir. Son test verilerine göre ise şükür ile durumluk kaygı arasında negatif yönde, psikolojik iyi oluş arasında pozitif yönde anlamlı ilişki bulunurken, sürekli kaygı arasında anlamlı ilişki olmadığı görülmektedir. Sonuç olarak hazırlanan farkındalık eğitimi amacına ulaşarak öğrencilerin şükür düzeylerini artırmaktadır. Şükreden insanların daha çok mutlu ve sağlıklı olduğu düşünülürse sağlıklı bir toplumun inşası için şükür konusunda farkındalık oluşturulması önem arz etmektedir.
THE SPATIO-TEMPORAL NATURE OF MUSICAL UNDERSTANDING
Authors:   Lomonosov Moscow State University, Kosilova Elena V.
Published: October 2024

The nature of musical understanding is currently being intensively investigated in both analytic and continental philosophy. Many authors point out that such understanding has an important intellectual component. This article studies the question of spatial components of musical understanding. B. Wharf drew attention to the fact that we often carry out spatial objectification in the mind. A. Bergson wrote about the same. Music has a motive, musical phrases, often a melody, and all that can be represented in the form of a drawing. To understand music means to understand the logic of the unfolding of the melody, and “unfolding” is a spatial phenomenon. Husserl writes of a temporal horizon when listening to music, but the horizon is also a spatial phenomenon. Furthermore, Husserl points out that the fluid meaning of music remains “the same”, and in order to see it, one must step out of the flow of time to some fixed point. Such an exit is virtual, but possible. However, those are not ordinary spatial representations. The term “quasi-space” is used for them, reminiscent of Husserl’s double intentionality. In that quasi-space the pattern or gestalt of music is formed. At the same time, there is a certain transcendental point, a limit to which our exit from the flow of time tends.
NAMES OF COLLECTIVES IN THE USSR. COLLECTIVE PERSONALITIES IN THE SELF-PERCEPTION OF SOVIET SOCIETY (THE VIEW OF A.F. LOSEV’S “PHILOSOPHY OF THE NAME”)
Authors:   Ufa University of Science and Technology, Vakhitov Rustem R. ,   Ufa State Petroleum Technical University, Rodionova Anna E. ,   Bashkir State Pedagogical University named after M. Akmulla
Published: October 2024

The article deals with an issue of the labor collectives’ names in Soviet society. The fact that collectives have names indicates that the people of that society regarded them as personalities, because only a person can have a name. The ideas of the philosophy of myth and the philosophy of the name created by AF Losev are used as a theoretical and methodological basis. According to AF Losev, socialism is a society where material production is absolutized. Under socialism, a person is understood only as part of a labor collective, which is a collective personality and it is precisely the entity which gives the status of the personality to an individual. Through the name of the collective, the latter is integrated into social reality, communicates with other collectives and the state. The article classifies the names of collectives, suggests that such a phenomenon represented the secularization of the tradition of naming churches in Russian Orthodoxy
Orthogonal Decompositions of Regular Graphs and Designing Tree-Hamming Codes
Authors: Shabana Hanan , El-Shanawany Ramadan , Halawa Sahar
Published: October 2024

The paper introduces a concept of graph decomposition. That is orthogonal decompositions. Orthogonal decompositions of a graph H is a partitioning H into subgraphs of H such that  any two subgraphs intersect in at most one edge. This decompositions are called G-orthogonal decompositions of H if and only if every subgraph in such decompositions is isomorphic to the graph G. Such decomposition appear in a lot of applications; statistics, information theory, in the theory of experimental design and many others. An approach of constructing orthogonal decompositions of regular graph is introduced here. Application of this approach for constructing tree -- orthogonal decompositions of complete bipartite graph is considered. Further, the use of orthogonal decompositions for designing hamming tree-codes is also discussed along with examples. The study shows that such codes have an efficient properties when are used to detect and correct the errors that may occur during  a transmission of data through a network. Furthermore, we present a method for the recursive construction of orthogonal decompositions.
Common Fixed Point of Generalized Berinde Type Contraction and an Application
Authors: Alsamir Habes , Qawaqneh Haitham Ali , Al-Musannef Gawhara , Khalil Roshdi
Published: October 2024

In this paper, we introduce  $\lambda_{(s,\varphi,\psi,L)}$-generalized Berinde type contraction and obtain some common fixed point results for such class of contractions the setting of triangular $\alpha$-admissible mappings with respect to $\eta$ in the framework of $b$-metric spaces.  Our results generalize and extend some theorems in the literature. An example is given to support our result.
$c$-quasi $(\tau_1,\tau_2)$-continuous multifunctions
Authors: Pue-on Prapart , Sama-Ae Areeyuth , Boonpok Chawalit
Published: October 2024

Our main purpose is to introduce the concepts of upper and lower $c$-quasi $(\tau_1,\tau_2)$-continuous multifunctions. Moerover, several characterizations of upper and lower $c$-quasi $(\tau_1,\tau_2)$-continuous multifunctions are established.