bluuebunny/crossref_metadata_2025 huggingface dataset:
Case Article—You Can’t Take It with You
Authors: Wilder Coleen , Li Sailu
Published: August 2019

The primary goal of the accompanying case study, “You Can’t Take It with You,” is to help business students develop better problem-solving skills. Teaching quantitative courses to students not in a STEM (science, technology, engineering, mathematics) discipline can be a challenging task. Using concrete examples with spreadsheets is an effective teaching strategy that appeals to many business students. This case study offers a concrete and relevant exercise using the base package of Excel. It is multidisciplinary and flexible in its delivery, allowing instructors to effectively integrate it into their course(s). Topics that may be covered include simulation, data analysis, and the time value of money. Advanced Excel functions that may be used include PMT, NORMINV, VLOOKUP, Scenario Manager, Data Table, and Goal Seek. Overall, students believed the case was challenging and that it was a valuable learning experience.
On the Efficacy of Static Prices for Revenue Management in the Face of Strategic Customers
Authors: Chen Yiwei , Farias Vivek F. , Trichakis Nikolaos
Published: August 2019

We consider a canonical revenue management (RM) problem wherein a monopolist seller posts prices for multiple products that are for sale over a fixed horizon so as to maximize expected revenues. Products are differentiated and subject to joint capacity constraints. Arriving customers are forward looking and strategize on the timing of their purchase, an empirically confirmed aspect of modern customer behavior. In the event that customers were myopic, foundational work has established that static prices are asymptotically optimal for this problem in the regime where inventory and demand grow large. In stark contrast, for the case where customers are forward looking, available results in mechanism design and dynamic pricing suggest substantially more complicated prescriptions. Notably, these results apply to settings with merely a single product type, and they are also often constrained by restrictive assumptions on customer type. We demonstrate that static prices surprisingly remain asymptotically optimal in the face of strategic customers for a multiproduct setting and for a broad class of customer utility models. For the single-product case, we further show that an optimally set static price guarantees the seller revenues that are within at least 63.2% of that under an optimal dynamic pricing policy, irrespective of regime. For utility models outside the class we consider, we show that static prices need not be asymptotically optimal. Nevertheless, the class of customer utility models we consider is parsimonious, enjoys empirical support, and subsumes many of the models considered for this problem in existing mechanism design research. We allow for multidimensional customer types and for a customer’s disutility from waiting to be positively correlated with his valuation. Therefore, our findings are likely to be robust and provide for a canonical RM problem a simple prescription that is near-optimal across a broad set of modeling assumptions.

This paper was accepted by Yinyu Ye, optimization.
The Sheffield Caseload Classification Tool: testing its inter-rater reliability
Authors: Chapman Helen , Matthews Rebekah , Farndon Lisa , Stephenson John , Fowler-Davis Sally
Published: August 2019

Community nursing caseloads are vast, with differing complexities. The Sheffield Caseload Classification Tool (SCCT) was co-produced with community nurses and nurse managers to help assign patients on a community caseload according to nursing need and complexity of care. The tool comprises 12 packages of care and three complexities. The present study aimed to test the inter-rater reliability of the tool. This was a table top validation exercise conducted in one city in South Yorkshire. A purposive sample of six community nurses assessed 69 case studies using the tool and assigned a package of care and complexity of need to each. These were compared with pre-determined answers. Cronbach's alpha for the care package was 0.979, indicating very good reliability, with individual nurse reliability values also being high. Fleiss's kappa coefficient for the care packages was 0.771, indicating substantial agreement among nurses; it was 0.423 for complexity ratings, indicating moderate agreement. The SCCT can reliably assign patients to the appropriate skilled nurse and care package. It helps prioritise and plan a community nursing caseload, ensuring efficient use of staff time to deliver appropriate care to patients with differing needs.
Enacting evidence-based practice: pathways for community nurses
Authors: Teodorowski Piotr , Cable Clare , Kilburn Sally , Kennedy Catriona
Published: August 2019

Community nurses are expected to deliver evidence-based practice, which is challenging given the diversity and breadth of the evidence base from which they can draw. This study aimed to explore community nurses' experiences of implementing change in their practice. Qualitative semi-structured interviews (n=9) and focus groups (n=2) with community nurses (n=17) were conducted. Three pathways to introduce change in practice were identified by participants: bottom-up, top-down and collaborative pathways. These are based on the nature of the proposed change, the available evidence, ‘buy in’ from colleagues and issues around implementation. The findings identify approaches to implementing change in community nursing practice. Practitioners would benefit from support to navigate the complex process of change through managerial support, ongoing education, accessible online resources and support through a practice development role.
Constipation in community-dwelling adults with intellectual disability
Authors: Kelly Anne Marie
Published: August 2019

Individuals with intellectual disability can experience multifaceted physical, psychological, emotional health and wellbeing problems. Chronic constipation is one of the major health problems for this cohort of the population; it is linked with distress, discomfort, pain, faecal incontinence, anxiety, behavioural difficulties and severe gastrointestinal complications. A continence assessment process for constipation ensures that planning, implementation and evaluation strategies provide quality health outcomes for individuals and their families. Proactive treatment interventions range from increasing fluid intake, alterations in dietary intake, implementing toileting routine and medication management. Health promotion approaches need to be positively implemented for individuals with intellectual disability to promote a healthy lifestyle, improve nutritional intake, increase access to exercise programs and thus advance health, wellbeing and quality outcomes.
Reflection and mental health nursing. Part two: reflection in everyday practice
Authors: Fowler John
Published: August 2019

In the second part of this new series on reflection in mental health nursing, John Fowler examines two different perspectives of reflection that are used in everyday clinical practice. He explores how most nurses are aware of their use of reflection following a nursing action or an incident, but are less aware of their ability to use reflection during action. Further articles in the series will be available online and will examine the application of reflection to everyday clinical practice including making time, reflective techniques and reflective learning.
Nobody left behind
Authors: Pezaro Sally
Published: August 2019

High-quality research leads to high-quality midwifery practice. Dr Sally Pezaro outlines how you can get involved in producing the evidence that makes a real difference to women
Safer maternity care: addressing variation in community midwifery
Authors: Ledger Sara
Published: August 2019

As part of its aims, the mother and baby charity Baby Lifeline provides training for health professionals attending births in the community, ensuring they have all the equipment they need
Recommendations for the use of unmanned aeronautical systems equipped with photo recording equipment for assessing the condition of the runway coatings in the polar regions
Authors: KUPRIKOV Nikita M. , KUPRIKOV Mikhail Yu. , RABINSKIY Lev N. , ZHURAVSKIY Danila M.
Published: August 2019

A method has been developed and tested for determining the albedo of the underlying runway surfaces located in the polar regions with the help of unmanned aircraft systems and the combined use of a photo-recording device and actinometrical equipment. The relevance of the non-contact method for assessing melting and thawing of ice in the Arctic and Antarctic regions is substantiated. The proposed original method is based on the use of an available measuring technique, which makes it possible to correctly estimate the albedo, reducing by several times the time spent on collecting data on large areas in hard-to-reach areas. The theoretical probability of using the proposed technical solution, and the results of its test tests in the polar regions with the help of high-tech equipment and unmanned aircraft systems of the simplest technical means are considered. Based on obtained results, an analysis was made of the operation of unmanned aircraft systems for assessing the state of runways and the application of the concept to the potential improving of the ways to collect field data in polar regions. The developed method of the hardware-software complex provides the possibility of fast and high-quality data collection on large areas, on the runways of the Arctic and Antarctic airports by the contactless method.
Thermal protection of aircraft units using film cooling with regard to unsteady heat conductivity
Authors: RABINSKIY Lev N. , TUSHAVINA Olga V.
Published: August 2019

A simplified physical and mathematical model of combined thermal conductivity and filtering of a cooler with a strong dependence of dynamic viscosity on temperature during film cooling of bodies was developed. The model takes into account the inflow of the cooler into the gas-dynamic boundary layer and the evaporation of the resulting protective film of the cooler. Analytical solutions are obtained for the mass evaporation rate, the rate of non-isothermal filtration, and the temperature distribution in the body, taking into account filtration. The resulting relationships are calculated by iterative methods. Analytical solution of the problem permitted us to clearly establish the functional relationship of all the defining characteristics of the system for automatic cooling of bodies.
Dynamics of a cylindrical shell with a collapsing elastic base under the action of a pressure wave
Authors: ANTUFEV Boris A. , EGOROVA Olga V. , RABINSKIY Lev N.
Published: August 2019

In the dynamic and quasi-static statements, the issue of non-stationary deformation and stability of the solid propellant rocket engine (SPRE) was approximately solved. It is modeled by a thin, smooth cylindrical shell, inside of which, on a part of its length, there is an elastic base corresponding to a gradually burning powder charge. A pressure wave is moving along the outer surface of the body, simulated by the running load. The deformed state of the shell is considered axisymmetric and is determined on the basis of the moment theory of the shells. For diverse variants of mounting the ends of the shell in a closed form, expressions were obtained for the critical velocity of the load. Examples were considered.
Construcción de la alianza terapéutica en un caso de terapia familiar con un miembro con Trastorno Límite de la Personalidad
Authors: D’Ascenzo Iolanda , Vilaregut Puigdesens Anna , Álvarez Mitjans Gisela , Bodas Martínez Mar , Elias Millan Mar , Ureña Mallen Israel , Yagüe Franco Rocío
Published: August 2019

Este estudio tiene como objetivo comprender cómo se construye la alianza terapéutica en un caso de terapia familiar con un paciente diagnosticado de Trastorno Límite de Personalidad (TLP). A través del Sistema de Observación de la Alianza Terapéutica en Intervención Familiar (SOATIF- o), se analizó la evolución de cuatro dimensiones de la alianza terapéutica (Enganche en el proceso terapéutico, Conexión emocional con el terapeuta, Seguridad en el sistema terapéutico y Sentido de compartir el propósito de la terapia en la familia) en la primera, tercera y quinta sesión. Los resultados encontrados muestran cómo, de las cuatro dimensiones que mide el SOATIF-o, la Conexión emocional con el terapeuta y la Seguridad en el sistema terapéutico fueron las dimensiones más relevantes para construir una buena alianza terapéutica en las fases iniciales del tratamiento. Por un lado, la Conexión emocional fue clave para la construcción de la alianza terapéutica con la paciente diagnosticada de TLP y, por el otro, trabajar la Seguridad en el sistema terapéutico favoreció la alianza con toda la familia. En conclusión, este estudio permite aportar a la clínica del TLP un conocimiento más profundo sobre cómo se construye la alianza terapéutica en las primeras fases del proceso psicoterapéutico, elemento indispensable para el éxito de la terapia a la vez que especialmente difícil en este tipo de casos.
Criterios de idoneidad psicológica para padres en proceso de adopción en Colombia y su validez a través de ecuaciones estructurales
Authors: Londoño Arredondo Nora Helena , Méndez Mejía Claudia , Juárez Acosta Fernando , Utria Rodríguez Oscar Emílio , Hewitt Ramírez Nohelia
Published: August 2019

Objetivo: Establecer un modelo de predicción de la capacidad de los padres para establecer vínculos seguros con menores de edad, teniendo en cuenta criterios de idoneidad parental. Metodología: Participantes: 40 hombres (edad media 42 años; D.E. 4.76) y 40 mujeres (edad media 37.33 años; D.E. 4.79). Instrumentos: MCMI III y CUIDA. Resultados: Las características psicológicas que predicen la capacidad de los padres para establecer vínculos seguros fueron la tendencia alta en las puntuaciones del CUIDA (excepto en agresividad) y la tendencia baja en las puntuaciones del MCMI-III. Al considerar el MCMI-III como instrumento con carácter clasificatorio de inclusión/exclusión y observar la influencia de dicho instrumento junto con todas las dimensiones del CUIDA en la asignación de idoneidad, el modelo resultó con un buen ajuste (FMIN = 0.037, F0 = 0.000, PCLOSE = 0.662, RMSEA = 0.000, ECVI = 0.315, GFI = 0.985, AGFI = 0.945) y una varianza explicada de idoneidad del 70%. Conclusiones: Existen correlaciones significativas entre las dimensiones del CUIDA y del MCMI-III. El estado de salud mental puede considerarse uno de los mejores indicadores de carácter clasificatorio de inclusión/exclusión de idoneidad, y las variables del CUIDA ejercen una influencia sobre la idoneidad de manera que explican en alto grado la varianza de la misma.
As determinações epistemológicas da Justiça ambiental no Âmbito da complexidade dos valores do Meio Ambiente
Authors: Da Silva Delmo Mattos , De Araújo Dalinajara Oyama Homma , Silva Márcio Flávio Lima
Published: August 2019

O presente artigo examina as relações entre saber e justiça, a partir daquelas determinações epistemológicas da justiça ambiental no âmbito da complexidade dos valores do meio ambiente. Trata-se, portanto, de examinar as determinações epistemológicas da justiça ambiental diante necessidade de redimensionar os termos do meio ambiente através de uma reflexão dos efeitos da aplicabilidade da racionalidade instrumental. Sendo assim, torna-se possível problematizar as estratégias de poder como produto de ações políticas injustas, cujas consequências determinam os modos de apropriação e exclusão social do território de grupos sociais em estado de vulnerabilidade socioambiental orientada, sobretudo, por uma lógica global inerente à racionalidade capitalista.
DISTRIBUIÇÃO ESPACIAL DE CRIADOUROS DE AEDES AEGYPTI EM JAGUARUANA – CE – BRASIL E SUAS CORRELAÇÕES COM INDICADORES SOCIODEMOGRÁFICOS
Authors: Maia Carlos Vangerre de Almeida , De Lima Gledson Santos , Rocha Alisson Daniel Silva , De Oliveira Estelita Lara , Da Silva Márcia Cristina Freitas , Da Silva Hihara Henrique , Barros Gabriel Douglas Santiago
Published: August 2019

O Aedes aegypti é originário das selvas africanas, principal responsável pela disseminação de arboviroses (Dengue, Febre amarela, Zika e Chikungunya), capaz de se reproduzir em ambientes naturais ou depósitos artificiais. O controle das arboviroses passa pela capacidade de eliminar os Depósitos Positivos (DPs) para os culicídeos. O objetivo desse trabalho é mapear as áreas de risco para a ocorrência de DPs em três bairros contíguos, em Jaguaruana-CE, referente aos anos 2014 e 2015, mediante análises geoestatísticas, bem como aferir possíveis correlações entre variáveis sociodemográficas, constantes nos 14 setores censitários que se sobrepõem aos bairros e a ocorrência dos DPs, através da Correlação de Spearman, adotando o Intervalo de Confiança menor ou igual a 95%.  Os resultados comprovam a existência de uma possível área de risco, bem como, correlação entre a DPs e densidade populacional (ρ = 0,58; p = 0,03) e com a coleta de resíduos sólidos (ρ = -0,53; p = 0,05), coadunando para o entendimento de que o mosquito, por meio da oferta de seres humanos para praticar a hematofagia e existência de depósitos para sua ovipostura, não precisa se deslocar muito. Ou seja, as atuais condições são favoráveis para sua perpetuação na região estudada, cabendo ao poder público local se munir de estratégias para o combate ao culicídeo.
Obstáculos epistemológicos sobre a água em livros didáticos de ciências do sexto ano do ensino fundamental, no PNLD 2017 do Brasil
Authors: Quevedo dos Santos Natiely , Schneider Eduarda Maria , Aparecida Della Justina Lourdes
Published: August 2019

O presente artigo aborda um estudo epistemológico do conteúdo sobre a água presente em sete livros didáticos da disciplina de Ciências que foram aprovados pelo Programa Nacional do Livro Didático 2017 no Brasil, do sexto ano do ensino fundamental. Ressaltamos a importância da análise de livros quanto aos obstáculos epistemológicos, tendo em vista que, podem representar um entrave à construção do conhecimento, dificultando o processo de ensino-aprendizagem, no entanto, quando estes são identificados, podem colaborar para mudança na postura tanto do professor quanto do aluno em relação ao conteúdo estudado, e contribuir para melhorar o ensino de Ciências. Nosso objetivo foi o de evidenciar se existe a presença ou não de obstáculos epistemológicos sobre o tema da água nos livros didáticos, tendo em vista que estes são um dos recursos mais utilizados em sala de aula para nortear o ensino nas escolas. A pesquisa teve caráter qualitativo, baseando-se na análise de conteúdo, na qual, evidenciou a presença do obstáculo do conhecimento quantitativo nos sete livros analisados e que apresentam também, os demais obstáculos propostos por Bachelard, sendo o obstáculo substancialista, evidenciado em seis dos sete livros analisados, já o obstáculo do conhecimento geral foi encontrado em quatro obras analisadas, o obstáculo verbal pode ser observado em três e tanto os obstáculos de experiência primeira, unitário e pragmático, realista e animista foram evidenciados em uma obra dentre as sete analisadas. Estudos relacionados aos obstáculos epistemológicos devem ser encarados como uma maneira de permitir avanços na formação de alunos e professores alertando para uma maior preocupação com o processo de ensino-aprendizagem e com recursos utilizados em sala de aula, como o livro didático, possibilitando a reflexão quanto a sua escolha e maneira de utilização.
Can we teach students to think like scientists while learning science?
Authors: Etkina Eugenia
Published: August 2019

In the past 20 years the educational community has accumulated enough data to say with conviction thatinteractive engagement methods lead to better student learning gains than traditional transmission-modemethods (MICHAEL, 2006; FREEMAN et al., 2014). As MITCHELL WALDROP (2015) said “At this point itis unethical to teach in any other way.” But what is this way? There are many models of interactive engagement methods. One popular approach is the “flipped classroom” (FULTON, 2012). In the flipped classroom students read the textbook (or watch a video with the instructor explaining the material), then come to class and discuss what they read through answering questions posed by the instructor. They often work in pairs and participate in voting for the best answer. An example of a flipped classroom in physics education is the method of Peer Instruction (MAZUR, 1997). While the students in these classrooms work collaboratively answering questions and the professor limits lecturing to a minimum, the knowledge that students begin with comes from authority. Students get acquainted with physics concepts by reading the book or watching a video with an authority figure on the screen. While such methods lead to more learning than traditional lecturing, what message about physics are they sending to the students? One answer is that science is an area of study that can be learned by reading the book and discussing what you read in class. Is this the message we want our students to get from our science classes?
Effect of Exercise on Lipid Peroxidation
Authors: Demir Süleyman , Turgut Günfer , Yurtseven Özlem , Aslan Diler , Genç Osman
Published: August 2019

Purpose: The effect of physical exercise on lipid peroxidation was investigated. Method: 27 healthy young adult male subjects were included in this study. Urine samples were collected before and after exercises. Urinary malondialdehyde and creatinine levels (Cr) were measured. Results: Urinary malondialdehyde levels were increased by exercise. While pre-exercise malondialdehyde levels were 5.02±1.26 nmol/mg Cr, post-exercise levels were 6.13±1.84 nmol/mg Cr (p<0.05). Conclusion: These findings indicated that physical exercise induced lipid peroxidation.
Selection criteria of some advance lines of sesame by the study of correlation and path coefficient analysis
Authors: Roy Barnali , Pal Amit Kumar
Published: August 2019

Sesame (Sesamum indicum L.) is one of the major oil yielding plant in India, but the production of sesame seed is very low. Now it is necessary to establish the selection criteria that directly or indirectly increase the seed yield per sesame plant. In this study, freshly harvested seeds of 21 stable advance lines of sesame and their 8 parents such as R-9, B-14, B-9, B-67, T-12, IDP-51, IET-2, HT-1 were taken to evaluate the selection criteria for higher seed yield. The results indicated that number of branches/plant, number of capsule/plant, number of seeds/capsule and 100 seed weight were strongly related with sesame yield. Thus, selection of advance lines of sesame, that have higher seed yield, can be done on the basis of number of branches/plant, number of seeds/capsule, 100 seed weight and harvest index. Moreover, these traits may be employed as the selection criteria for the betterment of sesame seed yield in future agricultural system.
Urban mobility: service level and demand forecast study on a road in the city of São Paulo
Authors: Gomes Alcir das Neves , Araújo Elson , Souza Osmar Martins , Garo Júnior Wagner Roberto
Published: August 2019

The theme urban mobility has been gaining prominence in recent times due to the impact it causes on the quality of life of people living in large centers, this article aims to study and evaluate the Capacity and Level of Service in a specific route in the city of São Paulo based on the concepts and methods established in Highway Capacity Manual 2000 (HCM 2000), in addition to using linear regression to estimate the forecast of short-term traffic demand in a biennial scenario, to propose alternatives to provide a satisfactory Service Level compatible with the forecast demand, to analyze the efficiency of the method as a tool in the decision-making process in the measures for the improvement of circulation and retardation in the municipal road system. In this exploratory, quantitative and descriptive study, the calculations were performed using concepts and methods contained in HCM 2000 evaluating the efficiency of the method as a means of obtaining information to support decision-making regarding the improvement of urban mobility. The results showed a tendency to reduce the volume of vehicle flow in the studied road. The results obtained demonstrate that the tools applied in the present work can be of great value for decision making or proposition measures for improvements in the attendance of demand in the capacity of the roads to provide a Service Level that allows to improve the satisfaction of the users of the road system of the municipality of São Paulo.
Simulation model of a stop production line: the relationship between financial return and productivity
Authors: Santos Bruno Miranda , Garlet Taís Bisognin , Klein Luciano , Silveira Franco , Rodrigues Paulo Cesar Chagas , Bueno Wagner
Published: August 2019

Making innovations to become competitive is not always an easy task, and in the industrial sphere, this thinking becomes even more complex. In this sense, proper use in raw material transformation processes becomes very challenging for managers, since improving processes is a condition where more can be done with less. Thus, many organizations seek to develop improvements through existing activities using a variety of techniques that are addressed in the literature, such as value flow mapping, lean production, simulations, among others. Therefore, this article aims to study and apply the computational simulation, through the use of Tecnomatix Plant Simulation © software, to obtain the best relation between financial return and productivity of a upholstery production line. In the methodology of this work was carried out the structural proposition of five scenarios. For the construction of these, a current scenario of the production line was carried out and for each new scenario, operators were added with new tasks to be performed. Although the final results show a better financial return for scenario three, the results obtained in scenario five are significant in terms of productivity indicators, although the cost with extra operators is much higher than in the other scenarios. Thus, it was clear the relevance of applying simulation in the production line, since the model assisted the managers in the decision making.
Vaginal delivery after laparotomic myomectomy during pregnancy
Authors: Garofalo Anna , Petruzzelli Paolo , Chiadò Fiorio Tin Michela , Parisi Silvia , Garofalo Giulia , Viora Elsa
Published: August 2019

Background

Symptomatic myomas during pregnancy are a rare condition that could however turn into an emergency because of torsion, necrosis, growth and compression leading to acute abdomen, potentially threating for pregnancy. Surgeons are usually reluctant to perform myomectomy during pregnancy because of an increased uterine blood flow and volume can give rise to a potential risk for haemorrhagic complications, while uterine manipulation can determine adverse pregnancy outcome. However, in some rare cases surgery is compulsory.

Case presentation

Here, we described a case of a successful laparotomic myomectomy performed during pregnancy at 11 weeks of gestation when an acute abdomen occurred. Surgery was followed by regular obstetrics follow-up ended with a spontaneous vaginal delivery with no pregnancy complications.

Conclusion

Although few case reports are described in literature, other authors have performed a myomectomy during pregnancy, and fewer cases have had a subsequent vaginal delivery, so that nowadays there is no clinical evidence on which to base best practice. This case shows that vaginal delivery after a laparotomic myomectomy performed during pregnancy, in selected cases, can be considered as a feasible option.
Evaluation of the abdominopelvic region using MRI in patients with primary amenorrhea
Authors: Gündoğdu Elif , Emekli Emre , Oğuzman Mehmet , Kebapçı Mahmut
Published: August 2019

Background

This study aimed to evaluate the imaging findings of patients who underwent an abdominal and pelvic magnetic resonance imaging (MRI) due to primary amenorrhea.

Methods

The pelvic and abdominal images of 34 female patients (mean age 15.61 years, range 14–19 years) were retrospectively analyzed by a single radiologist blinded to the clinical and laboratory data of the patients (other than primary amenorrhea) to evaluate the etiology of primary amenorrhea. The anatomy and anomalies of the internal genital organs and other accompanying abdominopelvic anomalies were investigated.

Results

Gonadal dysgenesis was present in 14 patients (41.17%) and Müllerian duct anomalies (MDAs) were present in 20 (58.83%) (Mayer-Rokitansky-Kuster-Hauser [MRKH] syndrome in 13 [65%], distal vaginal obstruction [DVO] findings in five [25%], and obstructed hemivagina and ipsilateral renal anomaly [OHVIRA] syndrome in two [10%]). Seven patients with MRKH (53.84%) were of type 1 and six (46.15%) were of type 2. A total of eight additional anomalies (vertebral and renal) were detected, six in MRKH and two in OHVIRA syndrome cases. Endometrioma and hematosalpinx were observed in one of the five patients with DVO (5%).

Conclusions

Primary amenorrhea is a common symptom that affects both the physical and psychosocial status of individuals. Determination of the underlying etiology is the first step in planning treatment. The evaluation of internal genital organ anomalies involved in the etiology is important for sexual function and fertility. MRI is a non-invasive imaging modality that should be preferred in these cases as it provides detailed data about the anatomy and anomalies of internal genital organs due to its high soft tissue contrast resolution.
Elaboration of low-band-gap π-conjugated systems based on thieno[3,4-b]pyrazines
Authors: Cheminet Nathalie , Nogueira Sandra L. , Benaqqa Oumayma , El Malki Zakaria , Bourass Mohamed , Cassegrain Simon , Hamidi Mohammed , Bouachrine Mohammed , Sotiropoulos Jean Marc , Miqueu Karinne , Jarrosson Thibaut , Niebel Claude , Lère-Porte Jean-Pierre , Serein-Spirau Françoise
Published: August 2019

In order to understand the electronic contribution of the thienopyrazine building block on the electronic properties of π-conjugated systems, small molecules containing thiophene and thienopyrazine moieties are synthesized and jointly studied by theoretical (DFT) and experimental methods (UV-Vis, UPS). Taking advantages of these preliminar attractive results, four low band gap extended structures have been elaborated on the base of Donor-Acceptor-Donor sequences (DAD); these elongated π-conjugated molecules exhibit noticeable electronic and absorption properties spreading from the near UV to NIR regions.
Modeling methods for gravity flow of granular solids in silos
Authors: Golshan Shahab , Zarghami Reza , Saleh Khashayar
Published: August 2019

This paper provides a review on the flow of free-flowing particles inside silos. We have previously reviewed in detail the experimental studies in this field. In the present work, the focus is placed on the theoretical approaches allowing numerical simulation and modeling of these systems. Modeling of granular flow in silos is very significant due to the advantages of modeling compared to experiments. The simulation methods are divided into four main groups: analytical methods, finite element method, discrete element method, and hybrid models. In each section, the most significant researches are reviewed. The drawbacks and advantages of each method are discussed, and the effects of different parameters are reviewed. Finally, the perspective of future work and the main challenges in this area are discussed.
Association of the ATG9B gene polymorphisms with coronary artery disease susceptibility: A case-control study
Authors: Mehrabi Pour Mahsa , Nasiri Mahboobeh , Kamfiroozie Hajar , Zibaeenezhad Mohammad Javad
Published: August 2019

Introduction: Endothelial nitric oxide synthase (eNOS), the main regulator of cardiac cell functioning, is regulated post-transcriptionally by autophagy-related 9B (ATG9B) gene. The proper function of the heart is partly determined by the intact interaction of these molecules. The present study aimed to investigate the effects of ATG9B rs2373929 and rs7830 gene polymorphisms on the predisposition to coronary artery disease (CAD). Methods: In this hospital-based case-control study, 150 patients with CAD compared with 150 healthy subjects for the genotype distributions of rs2373929 and rs7830 polymorphisms using T-ARMS PCR and ARMS PCR, respectively. Results: Considering rs2373929 polymorphism, increased risk of CAD observed in the presence of TT genotype (OR: 3.65; 95% CI: 1.77-7.53; P < 0.001) and also in the recessive model for T allele (OR: 3.41; 95% CI: 1.76- 6.60; P < 0.001). The frequency of the T allele was higher in cases compared to controls (OR: 1.71; 95% CI: 1.24-2.28; P = 0.001). The genotype and allele frequencies of the rs7830 polymorphism did not differ between the two study groups. Conclusion: The ATG9B gene rs2373929 polymorphism might involve in the pathogenesis of the CAD and can be considered as a screening molecular marker in the subjects prone to CAD.
Robustness of Resonant Frequency Test for Strength Estimation of Concrete
Authors: Sajid Sikandar , Chouinard Luc , Carino Nicholas
Published: August 2019

The resonant frequency test (RFT) of molded concrete specimens is a nondestructive test (NDT) method for indirect strength estimation based on the fundamental mode characteristic resonance frequency. In this article, experimental, numerical, and analytical studies were performed to assess the sensitivity of test results to various factors involved in RFT. These factors included vibration modes of the specimen, sensor attachment techniques, contact time of the hammer impact, location of the sensor on the specimen, length to diameter ratio (L/D), and cross-sectional shape of the specimen. Experimental study included concrete specimen preparation in the lab and real-time RFT measurements for robustness of some of the aforementioned factors. Computation models developed using numerical simulations were verified by laboratory test and analytical results. The finite element method–based code, ABAQUS, was employed for computational modeling. Statistical analyses of the experimental results and parametric studies of the computational modeling were used to quantify the effect of the aforementioned factors on uncertainties of strength estimates using RFT measurements. The contact time of the hammer impact and the L/D of the specimen were found to have considerable effect on test results and hence on the concrete strength estimates.
ENDOCRINOLOGY AND ADOLESCENCE: Dealing with transition in young patients with pituitary disorders
Authors: Sbardella Emilia , Pozza Carlotta , Isidori Andrea M , Grossman Ashley B
Published: August 2019

Introduction

The transition age is the period between childhood to adulthood; it refers to a broad set of physical, cognitive and sociocultural modifications, arbitrarily defined as starting in late puberty and ending with full adult maturation. Pituitary disorders in adolescence represent a challenge that requires careful management during the transition to adult care.

Methods

Given the complexity of care of pituitary disorders in the transition age, we have reviewed the relevant medical literature focusing on aetiology, clinical manifestations, treatment strategies of GH deficiency (GHD), hypogonadotrophic hypogonadism (HH) in male and female adolescents, central hypothyroidism (CH), central adrenal insufficiency (CAI) and cranial diabetes insipidus (CDI) at this time. The objective of the present review is to provide an up-to-date evaluation of the transition period to evaluate the specific needs of adolescents with chronic pituitary disease in order to optimise their management.

Results

We provide an overview of current clinical management of GHD, HH, CH, CAI and CDI in the transition age.

Conclusions

Specific changes occur in pituitary function during the transition period. A holistic approach including discussion of patients’ concerns and emotional support should constitute a key component of managing pituitary disorders in adolescence. Special transition clinics where paediatric and adult endocrinologists work together, should be increasingly created and strengthened to bridge care, to promote continuity and adherence to treatment and to limit potential negative development, metabolic, skeletal and cardiovascular sequelae of discontinuity of care among adolescents with pituitary disorders.
Standard Fixed-Schedule Methadone Taper Versus Symptom-Triggered Methadone Approach for Treatment of Neonatal Opioid Withdrawal Syndrome
Authors: Wachman Elisha M. , Minear Susan , Hirashima Meshelle , Hansbury Aaron , Hutton Elizabeth , Shrestha Hira , Combs Ginny , Barry Karan , Slater Cheryl , Stickney Donna , Walley Alexander Y.
Published: August 2019

OBJECTIVES:

We compared hospitalization outcomes in infants with neonatal opioid withdrawal syndrome (NOWS) treated with a novel symptom-triggered methadone approach (STMA) versus a fixed-schedule methadone taper (FSMT).

METHODS:

This was a single-center quality-improvement study of infants pharmacologically treated for NOWS. Outcomes were compared over time by using statistical process control charts and between the baseline FSMT (July 2016–November 2017) and intervention STMA (December 2017–May 2018) groups, including median hospital length of stay (LOS), methadone treatment days, total milligrams of methadone, and need for adjunctive agents.

RESULTS:

There were 48 infants in the FSMT group and 28 in the STMA group. Infants treated with STMA had a median LOS of 10.5 days (interquartile range [IQR] 10.5) versus 17.0 days (IQR 3.9; P = .003) in the FSMT group, with a 9.2-day difference in methadone treatment days (2.5 [IQR 9.0] vs 11.7 [IQR 4.0]; P = .0001), meeting criteria for statistical process control special cause variation. The average number of symptom-triggered doses was 2.1 (SD 1.0). Six infants in the STMA group were converted to FSMT after failing a trial of STMA. Infants successfully treated with the STMA (N = 22) had a median LOS of 10.0 days (IQR 4.0) compared with 17.0 (IQR 3.9) in the baseline FSMT group (P < .0001).

CONCLUSIONS:

STMA was associated with a significant reduction in median LOS and amount of methadone treatment. A symptom-triggered approach to NOWS may reduce LOS and medication exposure.
Risk-Based Newborn Drug Testing in a Setting With a Low Prevalence of Maternal Drug Use
Authors: Wood Kelly E. , McMillin Gwendolyn A. , Krasowski Matthew D.
Published: August 2019

OBJECTIVES:

Our objective in this study was to determine the predictive value of an institutional risk-based newborn drug-testing tool for detecting maternal drug use during pregnancy.

METHODS:

For 5.5 months, the umbilical cords of all newborns born at the study institution were collected and analyzed at a national reference laboratory. In the context of usual clinical care, the decision to perform newborn drug testing is based on an institutional risk assessment tool. For the cohort without clinical indication for testing, cords were deidentified during the study period. Chart review was not performed. Study data were compared with a national data set during the same time period and to previous institutional data.

RESULTS:

We tested 857 newborns, 257 of which had 1 or more identified risk factors. There were no drugs or drug metabolites that were significantly more common in the cohort without risk factors than in the clinical cohort. Alprazolam, methamphetamine, hydrocodone, and oxycodone were all significantly more commonly found in the risk-identified cohort. Amphetamine, methamphetamine, and cocaine were not detected in umbilical cords from any of the 600 newborns that would not have been identified for testing. Tetrahydrocannabinol (1.0%; n = 6) was the only illegal substance in the institution’s state that would not have been detected.

CONCLUSIONS:

Performing universal newborn drug testing in the study population would have identified an additional 6 newborns who were exposed prenatally to tetrahydrocannabinol out of 600 who were additionally tested. In areas with a low prevalence of maternal drug use, universal testing may not be cost-effective.
How Young Children Learn Language and Speech
Authors: Feldman Heidi M.
Published: August 2019

Pediatric clinicians are on the front line for prevention of language and speech disorders. This review uses prevailing theories and recent data to justify strategies for prevention, screening and detection, diagnosis, and treatment of language and speech disorders. Primary prevention rests on theories that language learning is an interaction between the child’s learning capacities and the language environment. Language learning occurs in a social context with active child engagement. Theories support parent education and public programs that increase children’s exposure to child-directed speech. Early detection of delays requires knowledge of language milestones and recognition of high-risk indicators for disorders. Male sex, bilingual environments, birth order, and chronic otitis media are not adequate explanations for significant delays in language or speech. Current guidelines recommend both general and autism-specific screening. Environmental and genetic factors contribute to primary language and speech disorders. Secondary and tertiary prevention requires early identification of children with language and speech disorders. Disorders may be found in association with chromosomal, genetic, neurologic, and other health conditions. Systematic reviews find that speech-language therapy, alone or in conjunction with other developmental services, is effective for many disorders. Speech-language interventions alter the environment and stimulate children’s targeted responding to improve their skills.
Análise bifator da Escala Baptista de Depressão – Versão Idosos (EBADEP-ID)
Authors: Baptista Makilim Nunes , Santos Luisa Milani , Filho Nelson Hauck
Published: August 2019

Modelos bifator têm sido relatados na literatura como explicações plausíveis para a estrutura latente da depressão. O presente estudo busca expandir essa área de investigação, tendo como objetivo principal realizar uma análise exploratória bifator da Escala Baptista de Depressão - Versão Idosos (EBADEP-ID). Os participantes foram 311 idosos com idades variando de 60 a 90 anos, provenientes de cinco grupos populacionais de tipo clínico e não clínico. Os resultados mostraram um melhor ajuste aos dados para o modelo bifator com um fator geral e dois fatores específicos, quando comparado a uma simples solução unidimensional. Entretanto, todos os itens carregaram predominantemente no fator geral, ocorrendo poucas cargas significativas nos fatores específicos, o que sustenta a unidimensionalidade do instrumento. O escore geral da EBADEP-ID apresentou elevada consistência interna (0,95 pelo coeficiente alfa, e 0,98 pelo coeficiente ômega) e capacidade informativa, além de alta sensibilidade e especificidade. Implicações teóricas e práticas dos resultados, bem como limitações do estudo, são discutidas ao final.
Tribology behaviour investigation of 3D printed polymers
Authors: Hanon Muammel M. , Kovács Márk , Zsidai László
Published: August 2019

3D printing of Acrylonitrile Butadiene Styrene (ABS) and Poly Lactic Acid (PLA) were used to prepare specimens utilising fused deposition modelling (FDM) technology. Two colours of PLA filament were printed; white and grey, whereas ABS only in white colour. Determining the tribological properties of 3D printed samples have been carried out, through obtaining the frictional features of different 3D printable filaments. Alternating-motion system employed for measuring the tribological factors. Studying the difference between static and dynamic friction factors and the examination of wear values were included. A comparison among the tribological behaviour of the 3D printed polymers has been investigated. The printed white ABS and PLA specimens show insignificant differences in the results tendency. On the contrary, the grey PLA exhibits a considerable variation due to the incredible growth in the coefficient of friction and wear average as well.
Learning from Mom and Pop
Authors: Porter Kelly Celeste , Richards Melanie B.
Published: August 2019

There is an art in “making do.” Making do is a vernacular phrase heard frequently in the Southeast United States, especially in lower socioeconomic households. It means “making ends meet” when money is tight by using the resources on hand. We investigate the design of making do by small businesses in such contexts by analyzing their business signage. A trained designer may pass by these “mom and pop” shops and find the signage to be merely novel, but we find that there is much more to learn. We complete a case series analysis of mom and pop signage using in-depth methods, including autoethnographic accounts of each author’s lived experience with mom and pop signageand a subsequent content analysis using visual grounded theory methods in a highly reflexive approach. We discover three main themes in play: “radical resourcefulness,” “authenticity/humanity,” and the “amateur aesthetic.” Radical resourcefulness is a dramatic shift in use and reuse of materials. A design may be considered “authentic” or have a visible connection to “humanity” when viewers can see evidence of the human hand or human decision-making in the design artifact. Amateur aesthetic, is a term applied to untrained "designers" who transform readily available materials to achieve their design goals. Each of these themes is especially relevant to disciplines such as communications and marketing, illuminating possibilities of community partnership and collaboration. At the same time, approaching the significance of mom and pop signage in this way provides insights for the professional design discipline as a whole, presenting opportunities for new interdisciplinary research, teaching, and service.
Brief Communication: Impact of Sign Panel Luminance on Visual Comfort
Authors: Bullough John D.
Published: August 2019

Signs should produce useful visual information to road and sidewalk users without creating undue glare or visual distraction. In order to assist in navigation and wayfinding, signs must be sufficiently conspicuous. For this reason their brightnesses are often higher than the surrounding visual environment. However, if the brightness becomes too high, the sign risks contributing to visual discomfort. Several published recommendations for limiting sign brightness include limits on the maximum illuminance from the sign (in lux). There is evidence, however, that the maximum luminance of a light source can also influence visual comfort. To investigate the potential role of maximum luminance, a pilot study was carried out to assess visual responses to sign panels producing the same illuminance but differing in luminance.
Uma Análise Generificada de Cuidadoras de Crianças com Desenvolvimento Atípico
Authors: Silveira Matheus Dos Santos da , Farias Yasmin Borges , Souza Ruth Daisy Capistrano de
Published: August 2019

O desenvolvimento humano é um fenômeno multifacetado, envolvendo processos de mudanças biológicas, psicológicas, sociais e culturais, ocorridos nas interações entre pessoas e sistemas biológicos, dentro de grupos sociais e ambientes, ao longo do ciclo da vida. O sistema familiar é visto como um dos ambientes centrais para a pessoa em desenvolvimento, dado o estabelecimento de relações entre a criança, desde o início de sua vida, e seus cuidadores. O objetivo deste estudo foi analisar, a partir dos estudos de gênero e do modelo bioecológico do desenvolvimento humano, os papéis desempenhados por cuidadoras de crianças com desenvolvimento atípico, no contexto da Amazônia brasileira. Os estudos sobre o cuidado de crianças com desenvolvimento atípico mostram o quanto esse fator age como um divisor no exercício da parentalidade, dados os aspectos socioculturais de gênero, raça e classe, onde se percebeu a maior parte das pessoas que exercem tais atividades, sendo mulheres. Concluiu-se que as práticas de cuidado ainda são atravessadas por toda uma carga de ações e respostas de uma rede de contextos cujas atividades, continuam sendo vistas como “domínios” femininos.