bluuebunny/crossref_metadata_2025 huggingface dataset:
The interplay between spatiotemporal overlap and morphology as determinants of microstructure suggests no ‘perfect fit’ in a bat-flower network
Authors: Diniz Ugo Mendes , Aguiar Ludmilla Moura de Souza
Published: February 2023

Plant–pollinator interactions in diverse tropical communities are often predicted by a combination of ecological variables, yet the interaction drivers between flower-visiting bats and plants at the community level are poorly understood. We assembled a network between Neotropical bats and flowering plants to describe its macrostructure and to test the role of neutral and niche variables in predicting microstructure. We found a moderately generalized network with internally nested modules comprising functionally similar plant and bat species. Modules grouped bats and plants with matching degrees of specialization but had considerable overlap in species morphologies and several inter-module interactions. The spatiotemporal overlap between species, closely followed by morphology, and not abundance, were the best predictors of microstructure, with functional groups of bats also interacting more frequently with plants in certain vegetation types (e.g., frugivores within forests) and seasons (e.g., long-snouted nectarivores in the dry season). Therefore, flower-visiting bats appear to have species-specific niche spaces delimited not only by their ability to exploit certain flower types but also by preferred foraging habitats and the timing of resource availability. The prominent role of resource dissimilarity across vegetation types and seasons likely reflects the heterogeneity of Neotropical savannas, and further research in biomes beyond the Cerrado is needed to better understand the complexity of this system.
Alpha kinase 3 signaling at the M-band maintains sarcomere integrity and proteostasis in striated muscle
Authors: McNamara James W. , Parker Benjamin L. , Voges Holly K. , Mehdiabadi Neda R. , Bolk Francesca , Ahmad Feroz , Chung Jin D. , Charitakis Natalie , Molendijk Jeffrey , Zech Antonia T. L. , Lal Sean , Ramialison Mirana , Karavendzas Kathy , Pointer Hayley L. , Syrris Petros , Lopes Luis R. , Elliott Perry M. , Lynch Gordon S. , Mills Richard J. , Hudson James E. , Watt Kevin I. , Porrello Enzo R. , Elliott David A.
Published: February 2023

Muscle contraction is driven by the molecular machinery of the sarcomere. As phosphorylation is a critical regulator of muscle function, the identification of regulatory kinases is important for understanding sarcomere biology. Pathogenic variants in alpha kinase 3 (ALPK3) cause cardiomyopathy and musculoskeletal disease, but little is known about this atypical kinase. Here we show that ALPK3 is an essential component of the M-band of the sarcomere and define the ALPK3-dependent phosphoproteome. ALPK3 deficiency impaired contractility both in human cardiac organoids and in the hearts of mice harboring a pathogenic truncatingAlpk3variant. ALPK3-dependent phosphopeptides were enriched for sarcomeric components of the M-band and the ubiquitin-binding protein sequestosome-1 (SQSTM1) (also known as p62). Analysis of the ALPK3 interactome confirmed binding to M-band proteins including SQSTM1. In human pluripotent stem cell-derived cardiomyocytes modeling cardiomyopathicALPK3mutations, sarcomeric organization and M-band localization of SQSTM1 were abnormal suggesting that this mechanism may underly disease pathogenesis.
Chalcogen Heterocycles Containing Main Group Elements: Synthesis and Reactivity
Authors: Puylaert Pim , Beckmann Jens , Hupf Emanuel
Published: February 2023

This chapter covers the compound class of chalcogen heterocycles, which also contain other main group elements. This chapter presents recent developments in the synthetic protocols, reactivity, and structure of selected chalcogen heterocycles, while concentrating on the p-block elements of groups 13, 14, and 15. Furthermore, the main focus is on the heavy chalcogens selenium and tellurium.
Electrophilic Chalcogen-containing Reagents
Authors: Rafique Jamal , Azeredo Juliano B. , Saba Sumbal
Published: February 2023

The design and synthesis of organochalcogen compounds (S, Se, Te) have attracted considerable attention from the scientific community due to their diverse applications in biological, chemical, and material science. Among the different strategies to access the C − Chalcogen bond, the use of electrophilic organochalcogen species is prominent. In this regard, the current chapter will highlight recent advances in the formation of C − Chalcogen bonds via electrophilic organochalcogen species. In addition, the use of bench stable electrophilic organochalcogen species as well as in situ generation and their uses are covered in this chapter.
Chalcogen-based Probes
Authors: Malankar Gauri S. , Cugnasca Beatriz S. , Wodtke Felipe , Petrarca de Albuquerque João L. , Deshmukh Pratiksha P. , Shelar Divyesh S. , Dos Santos Alcindo A. , Manjare Sudesh T.
Published: February 2023

Recently, selenium and tellurium atoms have been incorporated in various fluorophores such as rhodamine, cyanine, fluorescein, BODIPY, coumarin, and BOPHY for the detection and quantification of different analytes of biochemical and environmental interest by fluorescence measurements. The relevance of the insertion of chalcogen atoms in fluorescent compounds refers to their excellent redox characteristics, conferring unique properties to the resulting compounds, as analytical/biochemical probes. Additionally, selenium plays pivotal roles in biochemical events interacting selectively with endogenous sulfur-based biomolecules. About tellurium, there are only rare reports of its occurrence in certain fungi when exposed to tellurium-rich environments. Besides that, contrary to certain comments, generically, tellurium (and many organic tellurides) present low or no toxicity. This chapter provides a summary of all reported organic chalcogenated (Se and Te) fluorescent sensors, focusing on those containing selenium or tellurium in their structure, used in the detection of important analytes from a biological and environmental point of view, including metallic ions, reactive oxygen species (ROS), reactive nitrogen species (RNS), and biothiols.
Structural Features of Chalcogen Bonds and Weak Interactions Involving Chalcogens
Authors: Aragoni M. Carla , Torubaev Yury
Published: February 2023

The structural features of chalcogen bonding (ChB) interactions in linear fragments R–Ch⋯Nu (Ch = S, Se, Te; R = C, N, O, S, Se, Te; Nu = N, O, S, Se, Te, F, Cl, Br, I) involving Ch⋯Nu distances shorter than the sum of relevant van der Waals (vdW) radii are reviewed. For the R–Ch⋯Nu fragments, the structural parameters dR–Ch and dCh⋯Nu are analyzed along with the values of the functions δR–Ch and δCh⋯Nu calculated by normalizing the differences between the involved covalent R–Ch and non-covalent Ch⋯Nu distances and the sum of the relevant covalent and van der Waals (vdW) radii, in order to compare the data involving different Ch atoms. A systematic comparison of the ChB found in isologue fragments R–Ch⋯Nu is presented sorted by the nature of the involved Ch atom, of the R atoms covalently bonded to the Ch, and of the Nu species playing the role of chalcogen bond acceptors.
Chalcogen Bond Donors in Organic Synthesis
Authors: Steinke Tim , Huber Stefan M.
Published: February 2023

Chalcogen bonding describes the noncovalent interaction of Lewis acidic chalcogen substituents with Lewis bases. Chalcogen bonding is similar to the well-established hydrogen bonding interaction but also possesses markedly different features. Therefore, chalcogen bonding has attracted more attention lately and several reports of its application in solid state structures, anion recognition, and anion transport have been presented. Moreover, intramolecular chalcogen bonding was already successfully applied in enantioselective organocatalysis in the 1990s, acting via the rigidification of reagents. In the last few years, it has finally also been utilized in an intermolecular fashion in organic synthesis, enabling the activation of several functionalities. In this chapter, we attempt to provide a broad overview of these applications of chalcogen bonding in organic synthesis.
Chalcogen-containing Therapeutic Molecules
Authors: Sancineto Luca , Nascimento Vanessa
Published: February 2023

While the use of sulfur in medicinal chemistry is largely recognized and accepted, selenium represents an emerging area of investigation. The most recent advances in the potential use of these derivatives as anti-COVID19 agents as well as in the potential use for neurodegenerative diseases are reported here.
Supercritical carbon dioxide-decellularized arteries exhibit physiologic-like vessel regeneration following xenotransplantation in rats
Authors: Sung Shih-Ying , Lin Yi-Wen , Wu Chin-Chen , Lin Chih-Yuan , Hsu Po-Shun , Periasamy Srinivasan , Nagarajan Balaji , Hsieh Dar-Jen , Tsai Yi-Ting , Tsai Chien-Sung , Lin Feng-Yen
Published: February 2023

ScCO2-decellularized artery graft having tremendous application in vascular regenerative medicine.It with physiological-like responses, including high potential of biocompatibility and long-term patency, lower risk of aneurysm after xenotransplantation.
TCPP/MgO-loaded PLGA microspheres combining photodynamic antibacterial therapy with PBM-assisted fibroblast activation to treat periodontitis
Authors: Wang Wanmeng , Song Yunjia , Tian Yuan , Chen Bo , Liang Yunkai , Liang Yu , Li Changyi , Li Ying
Published: February 2023

The established multipurpose PMT microspheres could fulfill dual functions upon the same laser resource illumination: evoking photodynamic antibacterial function and exerting a fibroblast activation effect through the concerted work of Mg2+ and PBM.
Dynameric G-quadruplex–dextran hydrogels for cell growth applications
Authors: Sardaru Monica-Cornelia , Morariu Simona , Carp Oana-Elena , Ursu Elena-Laura , Rotaru Alexandru , Barboiu Mihail
Published: February 2023

Hybrid dextran–G-quartet dynamers produces tunable biocompatible three-dimensional thixotropic hydrogels, able to support cell growth.
Visualizing chiral structures in cellulose nanocrystal films by a Mueller matrix microscope
Authors: Feng Xiaowei , Wang Ting , Hao Mengyuan , Xue Nichang , Zhu Haidan , Tian Yang , Cui Xiaoyan
Published: February 2023

The structure of a CNC film is visualized by a Mueller matrix microscope (MMM). MMM suggests the dominance of tilted and systematic misorientation of the helixes in CNC films, offering a general strategy for the structural analysis of chiral materials.
A tribenzocoronene-based 2D conductive metal–organic framework for efficient energy storage
Authors: Zhao Jing , Zhang Ting , Ren Junyu , Zhao Ziqiang , Su Xi , Chen Weihua , Chen Long
Published: February 2023

We developed a new 2D c-MOF (Cu-TBC) via coordination polymerization of highly conjugated tribenzocoronene-type organic ligand (6OH-TBC) and Cu2+, which exhibits excellent stability and performance as the electrode for supercapacitor.
Growth and luminescence properties of γ-CuBr single crystals by the Bridgman method
Authors: Zhou Haichao , Chen Xinxin , Zhao Tao , Chen Can , Han Jiali , Pan Shangke , Pan Jianguo
Published: February 2023

γ-CuBr single crystals were successfully grown from melt by the Bridgman method with a 75% optical transmittance. γ-CuBr crystals have emission peaks at around 460 nm, 495 nm and 660 nm. The decay time of the free exciton is about 9 ns.
Surface specific adsorption of glucose to ZnO
Authors: Mandal Sasthi Charan , Chakrabarti Jaydeb
Published: February 2023

Potential of mean force (PMF) of glucose to four common surfaces of ZnO, has been calculated by using umbrella sampling technique. We observe that glucose shows maximum adsorption free energy for ZnO (10-10) surface that can be utilized as a non-enzymatic glucose biosensor.
Identification of a secondary Q-marker in high-quality ecotypes of Carthamus tinctorius L. and exploration of the target preference
Authors: Zeng Tiexin , Xiao Qi , Zhang Jianuo , Sun Xiao , Guo Baolin , Pei Jin , Huang Lin-Fang
Published: February 2023

Safflower (Carthamus tinctorius) has the efficacy for promoting blood circulation and preventing cardiovascular and Alzheimer's diseases and is thus a valuable medicinal and functional food plant.
Enhancing the foaming properties of brewer's spent grain protein by ultrasound treatment and glycation reaction
Authors: Li Qing , Li Wanying , Li Li , Zong Xuyan , Coldea Teodora Emilia , Yang Huirong , Zhao Haifeng
Published: February 2023

The foaming properties of brewer's spent grain protein (BSGP) were improved by ultrasound, glycation and ultrasound-assisted glycation treatments. Ultrasound and glycation improved the interfacial properties of BSGP and led to a more disordered structure.
Electromagnetic mill promoted mechanochemical palladium-catalyzed solid state cyanation of aryl bromides using non-toxic K4[Fe(CN)6]
Authors: Hou Yanan , Wang Hui , Xi Juan , Jiang Ruonan , Zhang Lizhi , Li Xinjin , Sun Fenggang , Liu Qing , Zhao Zengdian , Liu Hui
Published: February 2023

We have developed the first electromagnetic mill (EMM) promoted mechanochemical palladium-catalyzed solid state cyanidation of aryl bromides using non-toxic K4[Fe(CN)6] without additional heating.
A heuristic predictive model for screening green entrainers comparing life cycle assessment indexes and economics
Authors: Xu Qinggang , Xing Jiafu , Jiao Yuyang , Su Zihao , Zhang Yanli , Cui Peizhe , Qi Jianguang , Zhu Zhaoyou , Wang Yinglong , Ma Yixin
Published: February 2023

A heuristic predictive model proposed to screen green entrainer could avoid the formation of new azeotropic systems to minimize the impacts of TAC and LCA for separating azeotropes of the chemical process design.
Magnetic-nanowaxberry-based microfluidic ExoSIC for affinity and continuous separation of circulating exosomes towards cancer diagnosis
Authors: Ding Lihua , Liu Xia , Zhang Zhenzhong , Liu Li-e , He Sitian , Wu Yan , Effah Clement Yaw , Yang Ruiying , Zhang Aiai , Chen Wensi , Yarmamat Mubarak , Qu Lingbo , Yang Xiaonan , Wu Yongjun
Published: February 2023

A novel irregular serpentine channel microfluidic chip based on magnetic-nanowaxberry was developed to continuously separate plasma exosomes with large yield and optimum purity. It can be successfully applied to cancer diagnosis with high accuracy.
Design of Cu/ZnO/Al2O3catalysts with a rich Cu–ZnO interface for enhanced CO2hydrogenation to methanol using zinc-malachite as the precursor
Authors: Zhang Haotian , Han Caiyun , Li Congming , Wang Peng , Huang Hao , Wang Shuang , Li Jinping
Published: February 2023

By regulating the precursor structure, CZA-2-R can have a rich Cu–ZnO interface, which exposes more active sites for methanol synthesis.
Marine indole alkaloid diversity and bioactivity. What do we know and what are we missing?
Authors: Holland Darren C. , Carroll Anthony R.
Published: February 2023

Limited screening focus has led to most marine derived indole alkaloids (MIA) being inactive. However, computational comparisons with indole drugs suggest MIAs will be active in new disease relevant targets if a screening focus shift is adopted.
A molecular Popeye: Li+@C60 and its complexes with [n]cycloparaphenylenes
Authors: Freiberger Markus , Solymosi Iris , Freiberger Eva Marie , Hirsch Andreas , Pérez-Ojeda M. Eugenia , Drewello Thomas
Published: February 2023

We compare the stability of [n]cycloparaphenylene ([n]CPP)-based host–guest complexes with Li+@C60 and C60 in the gas and solution phase. Our experiments reveal a significant increase in stability for the complexes featuring [9–12]CPP with Li+@C60.
Aniline assisted dimerization of phenylalanines: convenient synthesis of 2-aroyl-3-arylquinoline in an I2-DMSO system
Authors: Ma Jin-Tian , Chen Ting , Chen Xiang-Long , Zhou You , Yu Zhi-Cheng , Zhuang Shi-Yi , Wu Yan-Dong , Xiang Jia-Chen , Wu An-Xin
Published: February 2023

I2-mediated catabolism and reconstruction of amino acids emerges again to furnish 2-aroyl-3-arylquinolines in a convenient way.
A novel polymer electrolyte with in situ polymerization and a high concentration of lithium salts for lithium metal batteries
Authors: Wang Chunhua , Li Donglou , Liu Na , Bai Guoliang , He Wenxiang , Zhou Xuehua , Wang Junwei , Zhang Jianli , Liu Xingjiang
Published: February 2023

A novel polymer electrolyte with high stability and high performance is prepared by in situ polymerization for lithium metal batteries.
The advent of recyclable CO2-based polycarbonates
Authors: Siragusa Fabiana , Detrembleur Christophe , Grignard Bruno
Published: February 2023

Here we describe the main synthetic approaches for the production of CO2-based polycarbonates and their emerging end-of-life scenarios by chemical re-/up-cycling.
Preparation of novel β-CD/P(AA-co-AM) hydrogels by frontal polymerization
Authors: Li Bin , Qin Haibo , Ma Ming , Xu Xiaojia , Zhou Mengjing , Hao Wenrui , Hu Zhigang
Published: February 2023

In this paper, betaine (Bet) was used as a hydrogen bond acceptor (HBA), and acrylic acid (AA) and acrylamide (AM) were used as hydrogen bond donors (HBD) and mixed to form a deep eutectic solvent (DES).
Emerging trends in direct air capture of CO2: a review of technology options targeting net-zero emissions
Authors: Abdullatif Yasser , Sodiq Ahmed , Mir Namra , Bicer Yusuf , Al-Ansari Tareq , El-Naas Muftah H. , Amhamed Abdulkarem I.
Published: February 2023

The increasing concentration of carbon dioxide (CO2) in the atmosphere has compelled researchers and policymakers to seek urgent solutions to address the current global climate change challenges.
Anaerobic demethylation of guaiacyl-derived monolignols enabled by a designed artificial cobalamin methyltransferase fusion enzyme
Authors: Grimm Christopher , Pompei Simona , Egger Kristina , Fuchs Michael , Kroutil Wolfgang
Published: February 2023

Lignin-derived aryl methyl ethers (e.g.coniferyl alcohol, ferulic acid) are demethylated under anaerobic conditions using a cobalamin dependent fusion enzyme, which combines the cobalamin carrier protein and the methyltransferase.
Investigating the magnetic and magnetocaloric behaviors of LiSm(PO3)4
Authors: Tran T. A. , Petrov Dimitar N. , Phan T. L. , Tu B. D. , Nhat H. N. , Tran H. C. , Weise B. , Cwik J. , Koshkid'ko Yu S. , Manh T. V. , Hoang T. P. , Dang N. T.
Published: February 2023

Evolution of magnetic entropy change |ΔSm| as functions of temperature and magnetic field for a LiSm(PO3)4 single crystal.
The effect of thread-like monomer structure on the synthesis of poly[n]catenanes from metallosupramolecular polymers
Authors: Tranquilli Marissa M. , Rawe Benjamin W. , Liu Guancen , Rowan Stuart J.
Published: February 2023

Varying the monomer structure in a metallosupramolecular polymer template allows access to poly[n]catenanes with different ring sizes and the preferential formation of branched poly[n]catenanes.
Confinement effect on hydrolysis in small lipid vesicles
Authors: Woods Ben , Thompson Katherine C. , Szita Nicolas , Chen Shu , Milanesi Lilia , Tomas Salvador
Published: February 2023

In lipid vesicles, the size and shape modulates the chemistry within.
Quantum chemistry simulation of ground- and excited-state properties of the sulfonium cation on a superconducting quantum processor
Authors: Motta Mario , Jones Gavin O. , Rice Julia E. , Gujarati Tanvi P. , Sakuma Rei , Liepuoniute Ieva , Garcia Jeannette M. , Ohnishi Yu-ya
Published: February 2023

We study the photodissociation of the sulfonium cation using quantum computing algorithms on IBM's hardware. We combine and extend methodologies to compute molecular excited states, photodissociation spectra, and molecular dissociation pathways.
Continuous nucleation of metallic nanoparticles via photocatalytic reduction
Authors: Simon Zoe C. , Paterno Ann Marie N. , McHugh Kaitlyn M. , Moncure Paige J. , Sen Riti , Patton Samuel T. , Lopato Eric M. , Talledo Savannah , Bernhard Stefan , Millstone Jill E.
Published: February 2023

We use photocatalytic reduction to synthesize mono and bimetallic nanoparticles. This approach reveals a new formation pathway involving continuous nucleation and allows the reaction to be turned on and off without impacting particle outcomes.
High-purity hydrogen production from real biomass pyrolysis vapors via a chemical looping process
Authors: Gao Zixiang , Zeng Dewang , Wu Shiliang , Ren Shaojun , Zhou Fu , Gao Ming , Song Feng , Zhai Yunfei , Xiao Rui
Published: February 2023

High-purity H2 could be obtained from biomass pyrolysis vapors via chemical looping with Fe–Al–Ni oxides as the oxygen carrier.
Cobalt(ii)-bridged triphenylamine and terpyridine-based donor–acceptor coordination polymer as an efficient trifunctional electrocatalyst
Authors: Singh Sugandha , Ghorai Manas K. , Kar Kamal K.
Published: February 2023

A new coordination polymer for trifunctional electrocatalysis (ORR, OER, and HER) synthesized via Schiff base condensation and in situ self-assembly using triphenylamine and Co(ii)-terpyridine ligand.
First-principles study for discovery of novel synthesizable 2D high-entropy transition metal carbides (MXenes)
Authors: Seong Hyun Woo , Lee Min Seok , Ryu Ho Jin
Published: February 2023

Through first-principles calculations, the synthesizability of high-entropy MXenes was evaluated and novel high-entropy MXenes were successfully synthesized.
Air-stable ternary organic solar cells achieved by using fullerene additives in non-fullerene acceptor-polymer donor blends
Authors: Trippodo Elisa , Campisciano Vincenzo , Feng Liang-Wen , Chen Yao , Huang Wei , Alzola Joaquin M. , Zheng Ding , Sangwan Vinod K. , Hersam Mark C. , Wasielewski Michael R. , Pignataro Bruno , Giacalone Francesco , Marks Tobin J. , Facchetti Antonio
Published: February 2023

Addition of a fullerene derivative to a PBTATBT-4F:Y6 blend significantly enhances cell stability, which retained 90% of the initial PCEs (13–14%) even after storage in air for 6 months, compared to only 20% retention for the binary device.
Highly efficient (EQE > 27%) Yellow OLEDs using spiro[fluorene-9,9′-phenanthren-10′-one]-carbazole-based donor–acceptor–donor host materials
Authors: Lin Yu Hsuan , Lin Wei-Han , Huang Yi-Sheng , Wu Chen-Hsun , Gnanasekaran Premkumar , Chang Yi-Min , Teng Sheng-Wei , Lu Chin-Wei , Chang Chih-Hao , Chang Yuan Jay
Published: February 2023

Four bipolar host materials, namely MS-CN, MS-OC, MS-PC, and MS-TPA were designed, synthesized, and their photophysical and electrochemical studies were investigated.
Thermoelectric properties of an organoboron polymer n-doped with a N-heterocyclic carbene based dopant
Authors: Li Jingyu , Wang Xueting , Dong Changshuai , Deng Sihui , Hu Junli , Liu Jun , Liu Yichun
Published: February 2023

A N-heterocyclic carbene based dopant can be n-doped into an organoboron polymer, achieving higher thermoelectric performance and better stability than those of N-DMBI.
Lanthanide-catalyzed deamidative cyclization of secondary amides and ynones through tandem C–H and C–N activation
Authors: Zhang Junxi , Wang Yitu , Zhou Xigeng
Published: February 2023

We report a new cyclization reaction of amides with ynones via tandem amide α-C–H and C–N activation enabled by a non-redox rare earth catalyst.
CO2 capture and conversion to syngas via dry reforming of C3H8 over a Pt/ZrO2–CaO catalyst
Authors: Dong Jingjing , Peng Yang , Li Juanting , Liu Zhong-wen , Hu Rongrong
Published: February 2023

Pt/ZrO2–5CaO could capture 10.3 mmol CO2 g−1 and convert it to syngas completely in C3H8 with little intensive energy swing.
Correction: Evaluation of the effects of newly synthesized metallophthalocyanines on breast cancer cell lines with photodynamic therapy
Authors: Bostancı Hayrani Eren , Bilgiçli Ahmet T. , Güzel Emre , Günsel Armağan , Hepokur Ceylan , Çimen Behzat , Yarasir M. Nilüfer
Published: February 2023

Correction for ‘Evaluation of the effects of newly synthesized metallophthalocyanines on breast cancer cell lines with photodynamic therapy’ by Hayrani Eren Bostancı et al., Dalton Trans., 2022, 51, 15996–16008, https://doi.org/10.1039/d2dt01912d.
Correction: Synergistic effect of polysaccharides and flavonoids on lipid and gut microbiota in hyperlipidemic rats
Authors: Bai Yun-fei , Yue Zhi-Liang , Wang Ya-nan , Li Yan-dong , Li Chong , Liu Xin-tong , Shi Ruo-han , Huo Ning-ning , Li Dan-dan , Gao Shan , Han Xue
Published: February 2023

Correction for ‘Synergistic effect of polysaccharides and flavonoids on lipid and gut microbiota in hyperlipidemic rats’ by Yun-fei Bai et al., Food Funct., 2023, 14, 921–933, https://doi.org/10.1039/D2FO03031D.
One-dimensional benzo[1,2-b:4,5-b′]dithiophene-based graphdiyne for electrochemical adsorption of chloramphenicol
Authors: Zhang Luwei , Liu Jingyi , Wang Kaihang , Wang Ning
Published: February 2023

One-dimensional benzo[1,2-b:4,5-b′]dithiophene-based graphdiyne (1D-BDT-GDY) shows enhanced electrochemical adsorption ability for chloramphenicol (CAP).
The first structural, morphological and magnetic property studies on spinel nickel cobaltite nanoparticles synthesized from non-standard reagents
Authors: Mouhib Yassine , Belaiche Mohammed , Elansary Moustapha , Lemine Mohamed Abdellah , Salameh Belal , Alsmadi Abdel Khaleq Mousa
Published: February 2023

In this paper, using a molten salt process, nickel cobaltite nanoparticles were successfully synthesized for the first time from non-standard reagents.
New insights into orthophosphoric acid assisted rapid aqueous processing of NMC622 cathodes
Authors: Tolchard Julian R. , Vullum Per E. , Arstad Bjørnar , Wagner Nils P.
Published: February 2023

Rapid aqueous processing of NMC with phosphoric acid pH adjustment requires careful control of stoichiometry and drying to avoid reactive phosphate residues, and consequent rapid cell death.
New shades of photochromism – yellow sodalites for the detection of blue light
Authors: Byron Hannah , Kreivilä Teppo , Colinet Pauline , Le Bahers Tangui , Lastusaari Mika
Published: February 2023

Sodalites showing white-to-yellow photochromism have been developed by partial substitution of sodium with calcium. The yellow colour is sensitive to fading under blue light, making these low-cost materials highly suitable for blue light detection.
TACC3–ch-TOG interaction regulates spindle microtubule assembly by controlling centrosomal recruitment of γ-TuRC
Authors: Rajeev Resmi , Mukhopadhyay Swarnendu , Bhagyanath Suresh , Devu Priya Manu Rani S. , Manna Tapas K.
Published: February 2023

γ-Tubulin ring complex (γ-TuRC), composed of γ-tubulin and multiple γ-tubulin complex proteins (GCPs), serves as the major microtubule nucleating complex in animal cells. However, several γ-TuRC-associated proteins have been shown to control its function. Centrosomal adaptor protein, TACC3, is one such γ-TuRC-interacting factor that is essential for proper mitotic spindle assembly across organisms. ch-TOG is another microtubule assembly promoting protein, which interacts with TACC3 and cooperates in mitotic spindle assembly. However, the mechanism how TACC3–ch-TOG interaction regulates microtubule assembly and the γ-TuRC functions at the centrosomes remain unclear. Here, we show that deletion of the ch-TOG-binding region in TACC3 enhances recruitment of the γ-TuRC proteins to centrosomes and aggravates spindle microtubule assembly in human cells. Loss of TACC3–ch-TOG binding imparts stabilization on TACC3 interaction with the γ-TuRC proteins and it does so by stimulating TACC3 phosphorylation and thereby enhancing phospho-TACC3 recruitment to the centrosomes. We also show that localization of ch-TOG at the centrosomes is substantially reduced and the same on the spindle microtubules is increased in its TACC3-unbound condition. Additional results reveal that ch-TOG depletion stimulates γ-tubulin localization on the spindles without significantly affecting the centrosomal γ-tubulin level. The results indicate that ch-TOG binding to TACC3 controls TACC3 phosphorylation and TACC3-mediated stabilization of the γ-TuRCs at the centrosomes. They also implicate that the spatio-temporal control of TACC3 phosphorylation via ch-TOG-binding ensures mitotic spindle assembly to the optimal level.
Optimal power flow‐based reactive power control in smart distribution network using real‐time cyber‐physical co‐simulation framework
Authors: Wagle Raju , Sharma Pawan , Sharma Charu , Amin Mohammad , Rueda Jose Luis , Gonzalez‐Longatt Francisco
Published: February 2023

Future distribution networks (DN) are subject to rapid load changes and high penetration of variable distributed energy resources (DER). Due to this, the DN operators face several operational challenges, especially voltage violations. Optimal power flow (OPF)‐based reactive power control (RPC) from the smart converter (SC) is one of the viable solutions to address such violations. However, sufficient communication and monitoring infrastructures are not available for OPF‐based RPC. With the development of the latest information communication technology in SC, cyber‐physical co‐simulation (CPCS) has been extensively used for real‐time monitoring and control. Moreover, deploying OPF‐based RPC using CPCS considering the controller design of SC for a realistic DN is still a big challenge. Hence, this paper aims to mitigate voltage violations by using OPF‐based RPC in a real‐time CPCS framework with multiple SCs in a realistic DN. The OPF‐based RPC is achieved by performing the CPCS framework developed in this study. The CIGRE medium‐voltage DN is considered as a test system. Real‐time optimization and signal processing are achieved by Python‐based programs using a model‐based toolchain of a real‐time DN solver and simulator. Real‐time simulation studies showed that the proposed method is capable of handling uncertain voltage violations in real time.
Design of advanced Aalborg inverter for extracting maximum power from renewable energy sources tied with autonomous grid system
Authors: Selvaraj Jaisiva , Chandrasekaran Kumar , Tamilarasan Ananth Kumar , Gheisari Mehdi , Fernández‐Campusano Christian , Liu Yang , Khodabakhshi‐Javinani Naser
Published: February 2023

Owing to increased energy demand, renewable energy sources have recently reached greater heights in the power industry. In this regard, integrating renewable energy with the power grid system has become essential in meeting consumer's energy demands. The novelty in this article is the design of an advanced Aalborg inverter with a reduced number of switches which results in enhanced system performance by reducing the switching losses. Integrating renewable energy sources with the power grid network has gained massive importance in supplying electric power to consumers. Integrating the power grid with renewable energy has become possible with the implementation of grid tie inverters. The only drawback in implementing renewable energy sources with the power grid is that the output of the resources varies from time to time in nature. Voltage Source Inverter‐based grid system requires two or three‐stage inverters for interfacing power units to transfer DC energy into the power grid network. To reduce the switching frequency across the system, many new excellent inverters have been designed to ensure the healthy operation of the system operating at a higher frequency. This article has been coined with the investigation of a novel buck and boosts converter‐based inverter operation named Aalborg inverter. The inverter operates at a higher frequency and minimum voltage drop across the inductor, where only one power stage has been implied to enhance the system's reliability and efficiency. This novel Aalborg inverter is applied and investigated for photovoltaic application.
Thermodynamic and experimental substantiation for obtaining ferrosilicon from tripoli
Authors: Mirkayev Nurseiit M. , Shevko Viktor M. , Aitkulov Dosmurat K. , Badikova Alexandra D.
Published: February 2023

The article examines the results of studying the possibility of obtaining ferrosilicon from tripoli. The studies included the thermodynamic modeling using the HSC-6.0 software package, based on the minimum Gibbs energy principle, and electric melting of tripoli in an arc single-phase electric furnace. The effect of temperature and the amount of carbon on the extraction degree of silicon into alloys and the silicon concentration in these alloys were determined. It was found that the interaction products of tripoli with carbon and iron under equilibrium conditions are mainly FeSi2, Fe3Si, FeSi, Fe5Si3, SiC, SiO(g), CaSiO2, MgSiO3, Al, Si, CO; the silicon extraction degree of 70–77% and its concentration in the alloy of 44.9–47.7% were achieved in the temperature range of 1830–2000 °C in the presence of 34–38% of carbon and 29% of iron; in the temperature range of 1700–1900 °C, the extraction degree of silicon into the alloy was 50–77.1%, and the concentration of silicon in the alloy at 1900 °C was 45–45.85%. During the electric melting of tripoli together with coke and steel shavings, depending on the composition of the charge, FS25 and FS65 ferrosilicon was formed.
Modified Dorsal Split Preservation Hybrid Rhinoplasty for Cartilaginous Pushdown and Full Letdown Applications: A PROM-Based Review of 100 Consecutive Cases
Authors: Robotti Enrico , Cottone Giuseppe , Leone Francesco
Published: February 2023

Splitting the middle vault on an anatomical plane along the “Septal T” allows a new hybrid perspective on the many modifications of “surface” preservation techniques. The “dorsal split preservation” concept can be applied both to cartilaginous pushdown as well as to full letdown techniques. The dorsal keystone area is maintained, while the middle vault is reshaped. The septum is addressed by conventional L strut septoplasty. Precise direct suture fixation of the high-middle strip is easily accomplished after flexing the osseous-chondral junction at the K area. Specific technical points are described to allow exact and stable configuration of the dorsum.

A retrospective analysis on 100 consecutive patients demonstrated aesthetic and functional improvement.
Pressure Masks for Facial Scar Treatment after Oncological Reconstruction: Long-Term Patient Satisfaction and Quality of Life
Authors: De Henau Melissa , van Kuijk Sander M.J. , Colla Carlo , Van den Kerckhove Eric , Van der Hulst Rene R.W.J. , Piatkowski Andrzej
Published: February 2023

Introduction With increasing incidence of facial skin cancer, more patients undergo facial reconstruction following Mohs micrographic surgery (MMS). Aesthetically unpleasing, thickened facial flaps, and disturbing scars can be treated with a pressure mask with inner silicone lining to help improve functional and aesthetic outcomes. However, data on long-term patient satisfaction and quality of life (QoL) following this treatment are lacking.

Methods We aimed to assess long-term satisfaction and QoL of patients who underwent local flap reconstruction following MMS. Patients treated between January 2012 and October 2020 were invited to answer FACE-Q and SCAR-Q questionnaires. Demographic data, skin cancer type and location, type of reconstruction, postoperative complications, duration of pressure mask therapy, daily compliance, and additional scar treatment were collected to explore possible predictors.

Results Of 92 eligible patients, 50 responded. Eighteen respondents were male (36%) and 32 were female (64%). Mean duration of pressure mask therapy was 10.20 ± 4.61 months. Patients were 61.14 ± 32.91 months after completion of pressure mask therapy upon participation. Patients whose reconstruction consisted of multiple flaps had significantly worse outcomes in social function (p = 0.012), scar appearance (p = 0.045), and scar symptoms (p = 0.008). A trend of increasing time since therapy completion predicting better outcomes was observed for all scales, and it was a significant predictor for better scar appearance (p = 0.001) and less scar symptoms (p = 0.001).

Conclusion Pressure mask treatment for facial flaps and scars following MMS results in good long-term patient satisfaction and QoL. Multiple local flaps, reflecting a larger skin defect postexcision, is a predictor for worse outcomes in social function, scar appearance, and symptoms. Increasing time is associated with increasing satisfaction, which reflects satisfactory and stable long-term effects of treatment, possibly combined with more acceptance of the result over time.
Estrogen-related Receptor Signaling in Skeletal Muscle
Fitness
Authors: Sopariwala Danesh , Nguyen Hao , Narkar Vihang
Published: February 2023

Skeletal muscle is a highly plastic tissue that can alter its metabolic and
contractile features, as well as regenerative potential in response to exercise
and other conditions. Multiple signaling factors including metabolites, kinases,
receptors, and transcriptional factors have been studied in the regulation of
skeletal muscle plasticity. Recently, estrogen-related receptors (ERRs) have
emerged as a critical transcriptional hub in control of skeletal muscle
homeostasis. ERRα and ERRγ – the two highly expressed
ERR sub-types in the muscle respond to various extracellular cues such as
exercise, hypoxia, fasting and dietary factors, in turn regulating gene
expression in the skeletal muscle. On the other hand, conditions such as
diabetes and muscular dystrophy suppress expression of ERRs in the skeletal
muscle, likely contributing to disease progression. We highlight key functions
of ERRs in the skeletal muscle including the regulation of fiber type,
mitochondrial metabolism, vascularization, and regeneration. We also describe
how ERRs are regulated in the skeletal muscle, and their interaction with
important muscle regulators (e. g. AMPK and PGCs). Finally, we identify
critical gaps in our understanding of ERR signaling in the skeletal muscle, and
suggest future areas of investigation to advance ERRs as potential targets for
function promoting therapeutics in muscle diseases.
Concise Synthesis of 1,4-Dideoxy-1,4-imino-l-arabinitol (LAB) from d-Xylose by Intramolecular Stereospecific Substitution of a Hydroxy Group
Authors: Akkarasamiyo Sunisa , Sakonnakhon Hatairat Promsaka Na , Kuntiyong Punlop , Ploypradith Poonsakdi , Samec Joseph S. M.
Published: February 2023

We report a concise and green total synthesis of 1,4-dideoxy-1,4-imino-l-arabinitol hydrochloride from naturally occurring d-xylose. The key step involves a stereospecific substitution of a hydroxy group, without prior derivatization, in which the only byproduct is water. This opens up a novel benign route to iminosugar derivatives with diverse biological activities.
Improvement in Nasal Obstruction and Quality of Life after Nasal Septoplasty with Turbinoplasty: A Pre- and Post-study
Authors: García-Chabur María A. , Castellanos Juliana , Corredor-Rojas Gloria , Salgar Mariana , Moreno Sergio , Pinzón Martín , Peñaranda Augusto
Published: February 2023

Introduction Septoplasty and turbinoplasty are common surgical interventions used to relieve nasal obstructive symptoms. Since it is difficult to measure the degree of nasal blockage, current literature wonders about the frequent performance of these procedures.

Objective To evaluate the perceived change in the nasal obstruction and the quality of life (QoL) of patients that underwent a septoplasty along with a turbinoplasty by applying subjective scales, to describe the correlation between those scales, and to study the impact of clinical factors in the postoperative outcomes.

Methods Prospective observational study. The Nasal Obstruction Symptom Evaluation (NOSE), the Visual Analog Scale (VAS), and the Glasgow Benefit Inventory (GBI) were assessed. The paired sample Wilcoxon test was used to evaluate the difference between the pre- and postoperative surveys. The correlation coefficient between the subjective scales was calculated. A quantile regression was performed to evaluate the effect of surgery on the results adjusted for clinical and demographic variables.

Results A total of 115 patients were interviewed. Postoperative NOSE scores were 45 points lower (95% confidence interval [CI]: - 53.53–- 35.46; p < 0.001) in comparison with the NOSE preoperative scores. Obesity was the only statistically significant factor associated with worse outcomes. Additionally, we found a high correlation between the NOSE and VAS scores and a negative correlation between the GBI and postoperative VAS scores.

Conclusion Nasal septoplasty, when paired with a turbinoplasty, decreases nasal obstruction and improves QoL. Obesity was associated with worse results. There was a strong correlation between the NOSE and the VAS results and between the GBI and postoperative VAS results.
Catalyst Comparison for Additive-Free Acceptorless Dehydro­genation of Indoline Derivatives
Authors: Blacquiere Johanna M. , Stubbs James M. , Nanuwa Amrit S. , Hoffman Matthew D.
Published: February 2023

A group of thirteen catalysts of type [Ru(Cp/Cp*)(P–P)(MeCN)]PF6, bearing cooperative or noncooperative bidentate phosphine ligands, were evaluated for the catalytic acceptorless dehydrogenation of indoline. The systematic comparison revealed that the optimal cooperative catalyst structure included a Cp ancillary ligand, and an N,N-disubstituted P,P-disubstituted 1,5-diaza-3,7-diphosphacyclooctane ligand, denoted as (PR
2NR′
2). A cooperative complex bearing a PPh
2NPh
2 ligand exhibited about a twofold longer lifetime than a noncooperative analogue with (diphenylphosphino)ethane (dppe) as the supporting bisphosphine ligand. The cooperative catalyst effectively dehydrogenated a range of indoline substrates to give substituted indoles.
Concise Synthesis of the Hexasaccharide Repeating Unit of the Capsular Polysaccharide of Klebsiella K19 Strain
Authors: Misra Anup Kumar , Sahaji Samim , Shit Pradip
Published: February 2023

A convergent [4+2] stereoselective block glycosylation strategy has been developed for the synthesis of the hexasaccharide repeating unit of the capsular polysaccharide of Klebsiella K19 strain in very good yield. The p-methoxybenzyl (PMB) group was used as a temporary alkyl protecting group, which was removed by tuning the glycosylation conditions. A thioglycoside was used as a glycosyl acceptor in an orthogonal glycosylation reaction. A late-stage TEMPO-mediated selective oxidation of a primary hydroxyl group into carboxylic acid allowed incorporation of the d-glucuronic acid moiety in the hexasaccharide. A combination of N-iodosuccinimide (NIS) and perchloric acid supported over silica (HClO4–SiO2) was used as a thiophilic promoter for the activation of thioglycosides. HClO4–SiO2 was also used as a solid acid activator for a glycosyl trichloroacetimidate derivative.
Presurgical Perspective and Postsurgical Evaluation of Plantar Plate and Turf Toe
Authors: Dimmick Simon , Reeve Ashton , Linklater James
Published: February 2023

Capsuloligamentous injury of the first metatarsophalangeal (MTP) joint (eponymously called “turf toe”) mostly occurs in athletes and involves acute trauma, whereas tears of the lesser MTP joint plantar plate typically are an attritional-degenerative condition. This article reviews the anatomy, pathophysiology, mechanism and patterns of injury, grading and classification of injury, imaging appearances (pre- and postoperative), and management of first MTP joint capsuloligamentous injuries and lesser MTP joint plantar plate tears. These two distinct pathologies are discussed in separate sections.
Manager des Jahres 2022: Heyo Kroemer: Meister des Understatements
Authors: Doelfs Guntram
Published: February 2023

Seit 2019 führt Prof. Dr. Heyo Kroemer erfolgreich die Berliner Charité. Leise im Ton, aber dennoch durchsetzungsstark treibt er die Entwicklung der Charité zu einem führenden Medizinstandort in Europa voran. In der Pandemie wurde er eine der wichtigsten Stimmen der Wissenschaft, die Politik schätzt seinen Rat.
Klimagerechte Gesundheitseinrichtigungen: „Es fehlt der Blick auf das große Ganze“
Authors: Hohnstein Aileen
Published: February 2023

Für den Geschäftsführer der Deutschen Allianz Klimawandel und Gesundheit (KLUG), Prof. Dr. Christian Schulz, führt an einem nachhaltigen Gesundheitswesen kein Weg vorbei. Bereits im Sommer 2021 hat er als Mitherausgeber das Rahmenwerk „Klimagerechte Gesundheitseinrichtungen“ veröffentlicht. Warum dringend schneller gehandelt werden muss, erklärt er im Gespräch mit kma.
Attractor-driven matter
Authors: Valani R. N. , Paganin D. M.
Published: February 2023

The state of a classical point-particle system may often be specified by giving the position and momentum for each constituent particle. For non-pointlike particles, the center-of-mass position may be augmented by an additional coordinate that specifies the internal state of each particle. The internal state space is typically topologically simple, in the sense that the particle’s internal coordinate belongs to a suitable symmetry group. In this paper, we explore the idea of giving internal complexity to the particles, by attributing to each particle an internal state space that is represented by a point on a strange (or otherwise) attracting set. It is, of course, very well known that strange attractors arise in a variety of nonlinear dynamical systems. However, rather than considering strange attractors as emerging from complex dynamics, we may employ strange attractors to drive such dynamics. In particular, by using an attractor (strange or otherwise) to model each particle’s internal state space, we present a class of matter coined “attractor-driven matter.” We outline the general formalism for attractor-driven matter and explore several specific examples, some of which are reminiscent of active matter. Beyond the examples studied in this paper, our formalism for attractor-driven dynamics may be applicable more broadly, to model complex dynamical and emergent behaviors in a variety of contexts.
Interaction effects from the elastodynamic scattering by two symmetric spherical cavities
Authors: Warren Thomas L.
Published: February 2023

The scattering of harmonic waves has been studied extensively for problems in quantum mechanics, acoustics, electromagnetics, and elasticity. Solutions to elastodynamic problems are the basis for ultrasonic non-destructive evaluation measurement models. Therefore, in this study, we investigate the use of the boundary element method (BEM) in the frequency domain using an off-boundary technique in which the observation points are taken inside the scattering object. This methodology removes both non-integrable singularities from the domain of integration along with avoiding ill-conditioning effects that occur at fictitious eigenfrequencies of which both require using special computationally demanding procedures to obtain solutions. Additionally, we employ both free and half-space fundamental solutions (Green’s displacement tensors) to investigate the elastodynamic scattering of an incident, plane, time-harmonic longitudinal wave in the frequency domain of a homogeneous, isotropic, and linear elastic solid with one or two spherical cavities. The half-space fundamental solution reduces the number of required boundary elements in half, which significantly reduces computational resource requirements. We only consider spherical cavities in this paper to illustrate the full and half-space off-boundary BEM and analyze the interaction effects associated with the elastodynamic scattering by two symmetric spherical cavities. To verify the validity of the free and half-space off-boundary BEM formulations, surface displacement results are compared with existing surface displacement results and show good agreement. Finally, the half-space off-boundary BEM is used to illustrate the interaction effects of the back and forward scattered displacement fields as a function of the distance from the spherical cavities.