bluuebunny/crossref_metadata_2025 huggingface dataset:
Rivalry and its mysteries: When Physics leverages Strategy
Authors: Mouillot Philippe
Published: October 2019

Dans cette recherche, les 5 forces du diagramme de Porter sont prises dans leur acception première, celle d’une énergie liée à une action ou un mouvement physique. Notre objectif est ici de construire un outil diagnostic de l’intensité concurrentielle permettant d’accompagner les processus décisionnaires. Pour cela, nous avons invité les Sciences Physiques à collaborer avec les Sciences de Gestion, un couple improbable comme la littérature en révèle pourtant beaucoup. Après étude des diagrammes Expert et Structuré, nous avons bâti une solution quantitative qui pourrait être un nouvel atout dans le diagnostic d’une intensité concurrentielle par le calcul du poids réel de chaque force. Une application théorique aux secteurs de l’art et du sel pose ici les bases de futures recherches.
A polycentric view of coordination in extreme action teams: Insights from pre-hospital emergency teams
Authors: Godé Cécile , Lenesley Pauline , Buthion Valérie
Published: October 2019

Cet article pose la question de recherche suivante : comment la polycentricité permet-elle d’affiner notre compréhension des liens entre les pratiques de coordination et les macro-arrangements dans les équipes extrêmes ? Il analyse la coordination entre des équipes d’urgence préhospitalières. Les résultats décrivent trois grandes pratiques de coordination et révèlent comment les macro-arrangements offrent aux équipes extrêmes une structure permanente de coordination.
ESTUDO RETROSPECTIVO: LEVANTAMENTO DOS ANIMAIS ATENDIDOS EM UM HOSPITAL VETERINÁRIO QUE POSSUEM VACINAÇÃO ANTIRRÁBICA - PERÍODO DE 2015 A 2016.
Authors: Lorga Andressa Duarte , Ferrari Melissa , Benedito Geovanna Santana , Gaddini Lucas Valeiras , Nakadomari Giovana Hashimoto , Cardozo Rejane Machado
Published: October 2019

A raiva se enquadra dentre as principais zoonoses com papel importante na saúde pública e animal. É uma doença viral, caracterizadapor um quadro agudo inflamatório no Sistema Nervoso Central e com potencial de acometimento a todos os mamíferos. Segundo o Ministério da Saúde em 2015 ocorreram dois casos de raiva humana no Brasil. No país, o cão é a principal espécie transmissora urbana, embora os morcegos sejam os responsáveis pela manutenção viral no ambiente silvestre e rural. O presente trabalho teve como objetivo avaliar a incidência de animais vacinados contra raiva nos atendimentos do Hospital Veterinário da Universidade Estadual de Maringá no período de 2015 a 2016, bem como verificar se a vacinação mostrou-se atualizada, estabelecendo correlação com a espécie, idade, sexo e ambiente em que vivem.Para tanto foram analisados os prontuários dos pacientes atendidos nos setores de pequenos e grandes animais durante o período referido. Do total de fichas analisadas, 26,2% dos pacientes possuíam a vacinação atualizada, ou seja, o tutor relatou ter vacinado seu animal no último ano, 37,9% dos pacientes apresentavam a vacinação antirrábica desatualizada e 31,3% dos prontuários não possuíam informação referente à vacinação. Diante desses dados pode-se inferir que a conscientização dos tutores sobre a vacinação antirrábica é importante e deve ser realizada.
A novel low cost roll-to-roll manufacturing compatible ultra-thin chip integration and direct metal interconnection process for flexible hybrid electronics
Authors: Palavesam N , Hell W , Drost A , Landesberger C , Kutter C , Bock K
Published: October 2019

The emerging Internet-of-Everything (IoE) framework aims to revolutionise human-machine interaction where billions of sensors and actuators placed on almost every physical object will be tasked to communicate with each other. A substantial fraction of these devices will be placed on locations that would undergo repeated bending deformation (such as sensors for prosthetics, human body and robots) or on curved surfaces (like interior as well as exterior of automobiles, buildings and industrial equipment). Therefore, flexible sensors and actuators delivering high performance at low power requirements and manufactured at low cost will be the key for successful implementation of IoE. Though massive developments achieved in printed and organic electronics have enabled them to fulfil the required flexibility and low cost demands of IoE applications, printed and organic electronics often fall short of the high performance and low power requirements demonstrated by silicon ICs. Flexible chip foil packages fabricated by integrating ultra-thin bare silicon ICs fulfil the aforementioned demands posed by IoE applications and therefore, they are often considered as potential enablers of IoE. Here, we present an innovative roll-to-roll manufacturing compatible low cost approach for direct metal interconnection and integration of ultra-thin silicon ICs. The thickness of the fabricated flexible packages with the integrated and interconnected ultra-thin ICs were as thin as 100 μm. Electrical measurements conducted on the 60 fabricated samples with interconnected flexible ultra-thin ICs revealed a very promising yield of 94%.
The role of the physiotherapist in the treatment of the terminally ill or dying child
Authors: Goodman M.
Published: October 2019

The role of the physiotherapist in the treatment of the dying child is twofold: Firstly, treatment is directed towards developing the child to full potential, maintaining function, preventing deformities and relieving pain and discomfort. Secondly, she has a role in supporting the parents and family. The need for a domiciliary physiotherapist is indicated.
Book reviews
Authors: Irwin-Carruthers S. H. , Maree H. P.
Published: October 2019

No abstract available
To be different
Authors: Compaan P.
Published: October 2019

Society (including health professionals) ascribes inferiority to the disabled in interaction, be it consciously or unconsciously, thus further complicating a difficult new situation, physically and psychologically. Examples are cited. A plea is made for more emphasis on psychosocial rehabilitation early on.
The global prevalence of dental healthcare needs and unmet dental needs among adolescents: a systematic review and meta-analysis
Authors: Ghafari Mahin , Bahadivand-Chegini Samira , Nadi Tayebeh , Doosti-Irani Amin
Published: October 2019

OBJECTIVES: Access to dental healthcare services is a major determinant of dental health in communities. This meta-analysis was conducted to estimate the global prevalence of dental needs and of unmet dental needs in adolescents.METHODS: PubMed, Web of Science, and Scopus were searched in June 2018. The summary measures included the prevalence of met and unmet dental needs. A meta-analysis was performed using the inverse variance method to obtain pooled summary measures. Out of 41,661 retrieved articles, 57 were ultimately included.RESULTS: The pooled prevalence of orthodontic treatment needs was 46.0% (95% confidence interval [CI], 38.0 to 53.0), that of general treatment needs was 59.0% (95% CI, 42.0 to 75.0), that of periodontal treatment needs was 71.0% (95% CI, 46.0 to 96.0), and that of malocclusion treatment needs was 39.0% (95% CI, 28.0 to 50.0). The pooled prevalence of unmet dental needs was 34.0% (95% CI, 27.0 to 40.0).CONCLUSIONS: The highest and lowest prevalence of unmet dental needs were found in Southeast Asia and Europe, respectively. The prevalence of dental needs was higher in the countries of the Americas and Europe than in other World Health Organization (WHO) regions. The prevalence of unmet dental needs was higher in Southeast Asia and Africa than in other WHO regions.
Case Report: Lower Gastrointestinal Bleeding due to Entamoeba histolytica Detected Early by Multiplex PCR: Case Report and Review of the Laboratory Diagnosis of Amebiasis
Authors: Madden Gregory R. , Shirley Debbie-Ann , Townsend Gregory , Moonah Shannon
Published: October 2019

We report a case of Entamoeba histolytica infection in a young man who presented with cerebral infarction and shortly after admission developed bloody diarrhea with fever. A rapid diagnosis of severe E. histolytica colitis was established through the use of a multiplex polymerase chain reaction enteropathogen stool panel. This result was unexpected in a patient native to the United States without known risk factors for amebiasis and negative stool microscopy examination for ova and parasites. Rapid diagnosis allowed prompt initiation of appropriate anti-amebic therapy and ultimately a good outcome in a condition that otherwise carries high morbidity and fatality.
Case Report: Spherocytic Hemolytic Anemia after Envenomation by Long-Nosed Viper (Vipera ammodytes)
Authors: Liapis Konstantinos , Charitaki Evangelia , Psaroulaki Anna
Published: October 2019

Snakebite envenoming is a major health issue in many parts of the world, especially in rural areas. Vipera ammodytes is the commonest cause of snakebite in Greece. We report our experience with a patient bitten by such a snake, who developed massive intravascular hemolysis characterized by a spherocytic rather than microangiopathic hemolytic picture. This case illustrates the potential of snakebite envenoming to cause spherocytic hemolytic anemia associated with hemoglobinuria and acute renal failure, and represents the first report of V. ammodytes in this context. Another important point is that antivenom was rapidly effective in reversing spherocytic hemolytic anemia, even though several hours had elapsed since the bite.
STRSW (Squeeze Type Resistance Spot Welding) Equipment Acceptance Criteria for the Collision Repair Industry
Authors:   Motor Vehicle Council
Published: October 2019

This SAE Recommended Practice provides a minimum standard for evaluating squeeze-type resistance spot welding (STRSW) equipment and minimum weld performance criteria for two-sided automotive collision repair welding. This document contains several standardized test methods that are designed for evaluating equipment performance in a laboratory environment.
A Comparative Survey on Flight Software Frameworks for ‘New Space’ Nanosatellite Missions
Authors: José Franzim Miranda Danilo , Ferreira Maurício , Kucinskis Fabricio , McComas David
Published: October 2019

Nanosatellite missions are becoming increasingly popular nowadays, especially because of their reduced cost. Therefore, many organizations are entering the space sector due to the paradigm shift caused by nanosatellites. Despite the reduced size of these spacecrafts, their Flight Software (FSW) complexity is not proportional to the satellite volume, thus creating a great barrier for the entrance of new players on the nanosatellite market. On the other side, there are some available frameworks that can provide mature FSW design approaches, implying in considerable reduction in software project timeframe and cost. This paper presents a comparative survey between six relevant flight software frameworks, compared according to commonly required ‘New Space’ criteria, and finally points out the most suitable one to the VCUB1 reference nanosatellite mission.
Drawing Difference
Authors: Meskimmon Marsha , Sawdon Phil
Published: October 2019

Drawing has been growing in recognition and stature within contemporary fine art since the mid-1970s. Simultaneously, feminist activism has been widespread, leading to the increased prominence of women artists, scholars, critics and curators and the wide acknowledgement of the crucial role played by gender and sexual difference in constituting the subject. Drawing Difference argues that these developments did not occur in parallel simply by coincidence. Rather, the intimate interplay between drawing and feminism is best characterised as allotropic a term originating in chemistry that describes a single pure element which nevertheless assumes varied physical structures, denoting the fundamental affinities which underlie apparently differing material forms. The book takes as its starting point three works from the 1970s by Annette Messager, Dorothea Rockburne and Carolee Schneeman, that are used to exemplify critical developments in feminist art history and key moments for drawing as a means of expression.

Throughout the chapters, these works are further explored in relation to the contemporary drawing practices of Marco Maggi, Sian Bowen, Susan Hauptmann, Cornelia Parker, Christoph Fink and Toba Kheedori. Their works are shown to be (re)iterative sites where mark-making differs with each appearance yet retains certain essential features. Dividing its analysis into the themes Approaching, Tropes and Coinciding, the book analyses how both drawing and feminist discourse emphasise dialogue, matter and openness. It demonstrates how sexual difference, subjectivity and drawing are connected at an elemental level and thus how drawing has played a vital role in the articulation of the material and conceptual dynamics of feminism.
Interventions to improve recruitment and retention of physicians in rural and remote Canada: a systematic review
Authors: Lafortune Claire , Gustafson Jeffrey
Published: October 2019

Purpose: Rural and remote regions of Canada struggle to attract and retain an adequate healthcare workforce to provide the healthcare needed by their local residents. The purpose of this systematic review is to explore current literature that has analyzed strategies for recruitment and retention of physicians to rural and remote regions in Canada.

Methods: Scopus and PubMed were searched for articles. To be included in the review, the titles yielded from the initial search had to be in English and meet one of the inclusion criteria: (1) address rural and/or remote healthcare, (2) focus on medical students or physicians, and (3) discuss recruitment or retention strategies. Titles were excluded that discussed non-OECD countries, or that were not original journal articles. The final sample of articles were analyzed by both reviewers for content and emerging themes.

Summary of Results and Conclusion: The initial search yielded a total of 3397 titles for review. After applying criteria described above, 35 articles remained for review. A variety of recruitment and retention themes were identified targeting physicians before, during, and after their medical education. The most effective strategies consistently appear to be those aimed before medical education, specifically admitting medical students who have a rural background. This review aims to provide a summary of the currently available research to assist with evidence-based decision making to increase supply and retention of rural physicians.
Which Types of Education are Important for Economic Growth?
Authors: Kurihara Yutaka
Published: October 2019

The relationship between education and economic growth has been discussed on numerous occasions, and there is a consensus that education plays an important role toward economic growth. This paper empirically examines 55 countries’ panel data to determine which types of education are playing important roles for achieving economic growth. The results showed that the improvement of educational systems, finance skill, Internet usage, and English proficiency has a positive impact on economic growth. On the other hand, educational systems and Internet usage also shrink inequality in the economy. High quality education for students is important for attaining economic growth, and it would confer student’s chances and opportunities and promote sound economic growth.
Access to the Supreme Court – Polish Approach
Authors: Zembrzuski Tadeusz
Published: October 2019

The article presents the evolution of cassation complaint in Polish civil procedure. The author describes the nature of this appellate measure and the requirements of its admissibility. Aditionally, the text provides an insight into a preliminary procedure designed to select cassation complaints, which will be subsequently examined by the Supreme Court on the merits. The author depicts the evolution of Polish cassation into an extraordinary appellate measure and analyses how it has affected access to the Supreme Court. He argues that the preliminary acceptance procedure does not constitute a limitation of the admissibility of the cassation complaint. It is an additional, independent instrument regulating access to the Supreme Court. In his view, selection of admissible complaints with regard to preliminary acceptance is a better solution than developing limitations related to the admissibility of cassation complaints. The author concludes that requirements for cassation complaints are high and difficult to fulfil. The special character of cassation complaint, the relevance of the institution of preliminary selection, as well as other limitations, justify the thesis that Polish procedural law provides only a narrow access to the Supreme Court.
Stereotactic Image-Guidance for Ablation of Malignant Liver Tumors
Authors: Paolucci Iwan , Sandu Raluca-Maria , Tinguely Pascale , Kim-Fuchs Corina , Maurer Martin , Candinas Daniel , Weber Stefan , Lachenmayer Anja
Published: October 2019

Stereotactic percutaneous ablation is a rapidly advancing modality for treatment of tumors in soft solid organs such as the liver. Each year, there are about 850,000 cases of primary liver cancer worldwide. Although surgical resection still is the gold standard for most cases, only 20–30% of patients are candidates for it, due to the advanced stage of the disease. Surgery can also be a huge burden to the patient and his/her quality of life might be temporarily severely reduced due to long hospital stays, complications, and slow recovery. To overcome these disadvantages, thermo-ablation of tumors of up to 3 cm has become a more viable alternative especially in the last decade, offering a potentially equally effective but minimally invasive and tissue sparing treatment alternative. In conjunction with improved CT imaging, stereotactic image-guidance techniques and image fusion technology were introduced to increase safety, efficacy, and accuracy of this treatment. Stereotactic image-guidance leads to a simple, fast, and accurate placement of the ablation probe into the liver tumor, which is a prerequisite for a complete destruction of the tumor by ablation. More and more physicians, including surgeons, consider ablation a viable alternative to resection whenever feasible. Patients undergoing such a minimally invasive treatment benefit from a shorter hospital stays, reduced complication rates, and faster recovery.
Sphaerellothecium reticulatum (Zopf) Etayo, a new lichenicolous fungusfor Antarctica
Authors: Halici Mehmet Gökhan , Barták Miloš
Published: October 2019

In the project aiming to determine the lichen mycota of James Ross Island, we identified a new lichenicolous fungus species which is reported from Antarctica for the first time: Sphaerellothecium reticulatum on Flavoparmelia gerlachei. Although this species was identified on other parmelioid lichens, it was never reported on Flavoparmelia spp.
Open top chamber microclimate may limit photosynthetic processes in Antarctic lichen: Case study from King George Island, Antarctica
Authors: Casanova-Katny Angelica , Barták Miloš , Gutierrez Catalina
Published: October 2019

Long-term manipulated warming experiments using the open top chamber (OTC) approach tend to mimick the future climate and predict the changes in photosynthesis and production of vegetation under globally changed climate. In Antarctica, several long-term experiments are carried out recently. Here we report to the lichens grown in OTCs installed at the Fildes Peninsula (King George Island). The field study compares primary photochemical processes of photosynthesis in Antarctic lichen Placopsis antarctica grown for one year in OTC and compared to outside plot (control). We measured effective quantum yield of photosystem II (ΦPSII) of green algae part of thallus in 10 min. interval for 12 days. We examined the responses of diurnal ΦPSII to PAR in relation to environmental factors through continuous 12-d-long monitoring of chlorophyll fluorescence parameters ΦPSII in particular. Daily courses of ΦPSII and photosynthetic electron transport rate (ETR) to photosynthetically active radiation (PAR) and hydration state of thallus have been assumed to reflect changes in physiological status of P. antarctica in changing Antarctic environment. The data indicate that OTC microenvironment may lead to partial limitation of photosynthetic processes in P. antarctica during austral summer season. The limitation is caused by accelerated dehydration of thallus in OTC compared to the outside generally colder control plot, and thus shortened physiologically active period of lichens in OTC.
An A Priori Measure of Visual Difficulty of 2-D Sketches Depicting 3-D Objects
Authors: Widder Mirela , Berman Avi , Koichu Boris
Published: October 2019

Aiming to enhance understanding of visual obstacles inherent in two-dimensional (2-D) sketches used in high school spatial geometry instruction, we propose a measure of visual difficulty based on two attributes of the sketches: potentially misleading geometrical information (PMI) and potentially helpful geometrical information (PHI). The difficulty of 12 normatively oriented cube-related sketches was theoretically ranked according to their ratios, #PHI/#PMI. The ranking was compared to the actual visual difficulty as measured by the percentage of correct or desired comprehension, individual spatial ability, and study-time allocation. This procedure was repeated for unnormatively oriented sketches, obtained by vertically flipping the original sketches. In both cases, the findings substantiate #PHI/#PMI as an a priori measure of visual difficulty. Practical, theoretical, and methodological implications are inspected and discussed.
Ficción e historia en el siglo XXI. El nomos narrativo en la novela española actual.
Authors: Navajas Gonzalo
Published: October 2019

Estudio de la metodología narrativa seguida por tres novelas españolas recientes con relación al tratamiento de la temporalidad histórica nacional centrada en dos episodios especialmente traumáticos de esa historia: la Guerra Civil y el terrorismo de ETA. Los textos son El monarca de las sombras de Javier Cercas, Patria de Fernando Aramburu y Eva de Arturo Pérez-Reverte. esos textos ficcionales plantean una versión histórica diferencial en la que se ponen en cuestionamiento las conclusiones y el enjuiciamiento convencionales de esos hechos. Al mismo tiempo, proponen una lectura hermenéutica abierta que puede generar nuevos modos de visualizar y evaluar la historia nacional

Study of the narrative methodology used in three recent spanish novels regarding their treatment of the national historical temporality focusing on two especially traumatic episodes of that history: the spanish Civil War and ETA terrorism. The novels are: El monarca de las sombras by Javier Cercas, Patria by Fernando Aramburu and Eva by Arturo Pérez-Reverte. These fictional texts advance a differential version of those episodes and they question the conventional conclusions and evaluation of the facts at hand. At the same time, those novels propose an open hermeneutic reading that may generate new ways of visualizing and evaluating spanish national history.
Prehistories of the Post-Digital:
Authors: Cox Geoff
Published: October 2019

In this short essay I want to try to speculate on what is being displaced in the post-digital and why this might be the case. It is not so much a critique of the post-digital but more an attempt to understand some of the conditions in which such a term arises. Is contemporary cultural production resigned to make empty reference to the past in ‘post-history’: thereby perpetuating both a form of cultural amnesia and uncritical nostalgia for existing ideas and mere surface images?
Post-Digital Is Post- Screen
Authors: Bosma Josephine
Published: October 2019

If the interest in the post-digital seems to point at anything, it is that the usefulness of the digital as a discursive element in analyzing the impact of technology in society and culture is waning. Digital technologies on the other hand only grow and proliferate. This raises the question: why do we need or want to discuss matters in terms of a post- digital condition if digital media do not seem to lose ground but rather expand? I suggest we use the term post-digital to establish new points of perspective to refine the analysis of digital media and digital technologies. I look at this issue in the context of art. Here, the digital realm tends to be perceived as screen-based. To examine and understand art practices in which screens are not at the center of a work a screen-based analysis does not seem to make much sense. I try to show the limitations of the screen-based approach of the digital through Alexander Galloway’s analysis of this problem in his book The Interface Effect.
Psycho-Academic Dérive – A Proposal
Authors: Bruno Christophe
Published: October 2019

This artistic intervention presents a Psycho-Academic Dérive (P.A.D.), a post-digital humanities project about the interrelations between art, academy and the corporate world. P.A.D. establishes a correspondence between dérive in physical space and dérive in conceptual space, which blurs the border between digital and post-digital — if ever it is possible to blur it more.
Grammatized Psychopath
Authors: Olsen Lea Muldtofte
Published: October 2019

This paper focuses on Jason Huff and Mimi Cabell rewriting of Brett Easton Ellis’s famous novel in their piece American Psycho 2010. Through the notion of grammatization, and drawinf on Jacques Derrida and Bernard Stiegler, it argues that this rewriting, moving from offline to online (and back to offline) literature through Gmail as a filter, not only manifests a here-and-now alternative, consumeristic portrait of Bateman co-authored by Google’s algorithms’ interpretation of the text, but also elucidates a reading and writing otherness.
Computing War Narratives
Authors: Young Dave
Published: October 2019

In this text, I will unpack the workings of a particular technological apparatus applied in South Vietnam during the war, contextualising it in the culture of systems-analysis which became prevalent in US defence strategy following the Second World War. This apparatus – called the Hamlet Evaluation System – was in formal operation from 1967 until 1973, and aimed to provide US Forces with a vital narrative of progress in their “pacification programmes” in Vietnam. With its disruptive use of computers, the immense scale and scope of its task, and its affordance of a managerial approach to warfare, this system raises a number of issues around the role of the computer as bureaucratic mediator – in this case, tasked with converting complex insurgencies into legible, systematic narratives. What kind of insights did it provide into the operations of the Vietcong insurgency? How does it fit into the wider ecologies of command and control in the US Military during the first few decades of the Cold War? As the Hamlet Evaluation System, almost fifty years after its inception, is still considered the “gold standard of [counterinsurgency]” (Connable 113), it remains an important case study for those trying to understand how computers structure the institutional bureaucracy of war, and how they are imagined as epistemological tools that can somehow reveal objective truths about the complex, dynamic reality of war.
Calculated error
Authors: Morgan Carleigh
Published: October 2019

This paper proposes a reconsideration of the aesthetic category of ‘glitch’ and advocates for a more careful theorisation around indexing — in the sense of both locating and naming — errors of a digital kind. Glitches are not as random as they seem: they are ordered and shaped by computational hardware and software, which impose a mathematical rubric on how glitches visually manifest and set ontological and technological constrains on glitch that limit how digital errors can and cannot be made to appear. Most crucially, this paper thinks about how one particular type of glitch — a compression artefact called a macroblock — can often appear as random, erratic, or unpredictable but is, in fact, materially constrained and visually conditioned according to the principles of computing and computer design. At its core, compression aesthetics can shed light on the operations of algorithms, the structures of digital technologies, and the priorities and patterns which occur as a function of algorithmic manipulation. The randomness, unpredictability, or messiness which glitch studies invokes around the glitch is in danger of overlooking the ways that the material architectures and algorithmic protocols structure the digital glitch by organising, constraining, and given form to its appearance.
« Tout emploi, quel qu’il soit » : l’injonction à l’emploi pour les prestataires d’aide sociale au Québec, 1990-2005
Authors: Charron Catherine
Published: October 2019

Entre 1989 et 2005, le régime d’aide sociale au Québec comportait des obligations relatives à l’occupation d’un emploi ou à la participation à des mesures de développement de l’employabilité. Durant cette période, des dizaines de milliers de prestataires ne s’étant pas conformés aux prescriptions de leur agent ou agente du ministère du Travail, de l’Emploi et de la Solidarité sociale ont vu leur prestation réduite. À partir d’une analyse des décisions rendues en appel par le Tribunal administratif du Québec à l’égard des prestataires sanctionnés, cet article propose de mettre en lumière l’irruption du virage néolibéral dans le dispositif de l’aide sociale, en s’attardant à la façon dont l’injonction à l’emploi est mise en oeuvre par les acteurs et actrices de ce dispositif.
Mise en oeuvre du programme de philosophie pour enfants : les effets sur l’enseignement selon trois enseignants du primaire
Authors: Lang Mathieu , Gagnon Samuel
Published: October 2019

Si les effets du programme de philosophie pour enfants sur les élèves ont fait l’objet de plusieurs études, peu d’études ont fait état du vécu des enseignants lors de l’implantation de tels programmes. De nature exploratoire, cette recherche qualitative interprétative avait comme objectif de jeter un regard sur le sens que les enseignants donnent à leur expérience lors de l’implantation du programme de philosophie pour enfants et d’explorer son influence sur leur enseignement. Ainsi, des entrevues ont été réalisées auprès de trois enseignants du primaire. Les résultats de ces entrevues montrent que la mise en oeuvre du programme de philosophie pour enfants a provoqué des modifications dans les méthodes et les stratégies pédagogiques des enseignants. Ils estiment prioriser un enseignement de la pensée qui favorise le dialogue entre les élèves en privilégiant la cohabitation des différents points de vue pendant et en dehors des communautés de recherche philosophique.
VERS UNE TYPOLOGIE DE LA CLIENTÈLE À PROFIL « MULTIPROBLÉMATIQUE » AU SEIN DU RSSS
Authors: Moreau1 Isabelle , Léveillée Suzanne
Published: October 2019

Issu d’un devis de recherche quantitatif, cet article présente les résultats d’une étude exploratoire portant sur une clientèle considérée comme étant hétérogène et mettant au défi le réseau de la santé et des services sociaux (RSSS), soit la clientèle dite « multiproblématique ». Une analyse typologique permet de proposer une classification de trois profils types. Cette typologie vise à faciliter l’organisation des services au sein du RSSS à l’égard de cette clientèle aux besoins particuliers, et aura certainement son importance, particulièrement dans le choix des approches et des modalités d’intervention à privilégier auprès de cette clientèle.
LIEN FRATERNEL ET RENÉGOCIATION IDENTITAIRE CHEZ DES JEUNES ADULTES IMMIGRANTS AU QUÉBEC
Authors: Ganem Rébecca , Hassan1 Ghayda
Published: October 2019

L’étude des remaniements identitaires qui accompagnent le vécu des immigrants est particulièrement pertinente au Québec, qui accueille chaque année plus de 48 000 immigrants d’après les chiffres du Ministère de l’Immigration, de la Diversité et de l’Inclusion du Québec (2017). Cette recherche qualitative conduite auprès de sept participants s’intéresse aux implications du lien fraternel sur la renégociation identitaire de jeunes adultes immigrants. Les résultats apportent des éléments de compréhension pour l’intervention clinique et la recherche sur des phénomènes complexes reliant les trajectoires migratoires individuelle et familiale, les relations fraternelles et la construction de soi.
Substancia, cambio y materia en las Analogías de la experiencia de la Crítica de la razón pura de Kant
Authors: Rivera de Rosales Jacinto
Published: October 2019

En el artículo se expone en diez momentos los conceptos de substancia, cambio y materia que aparecen en la Analítica transcendental de la Crítica de la razón pura de Kant, como categorías y esquemas y su funcionamiento en las Analogías de la experiencia. Se muestra cómo la categoría en general y la de substancia en particular en su idealidad transcendental es una estrategia para ordenar y objetivar el mundo fenoménico. Se afirma que también el cambio es necesario a priori y que tanto el cambio como lo permanente son finitos y limitados, así como todos los fenómenos, lo cual nos llevaría a la afirmación de que lo enteramente permanente es la materia, la materia transcendental, pero ésta no es un objeto sensible, de modo que la realidad empírica de la sustancia son los objetos sensibles que relativamente permanecen en el espacio-tiempo. Por último, la materia se presenta constituida por fuerzas, y dado que en ella no hay nada simple, podemos decir que la substancia no es sino un campo de fuerzas.
Development of a liquid chromatography/tandem‐mass spectrometry assay for the simultaneous determination of teneligliptin and its active metabolite teneligliptin sulfoxide in human plasma
Authors: Park Jin‐Woo , Kim Kyoung‐Ah , Park Ji‐Young
Published: October 2019

Teneligliptin is a recently developed dipeptidyl peptidase‐4 (DPP‐4) inhibitor for the treatment of type 2 diabetes mellitus. To study simultaneous pharmacokinetics of teneligliptin and its major active metabolite, teneligliptin sulfoxide in human plasma, we developed and validated a LC‐MS/MS method. The analytes were detected in the positive mode using multiple reaction monitoring (teneligliptin: m/z 427.2→243.1; teneligliptin‐d8: m/z 435.2→251.3; teneligliptin sulfoxide: m/z 443.2→68.2). The method demonstrated accuracy, precision, and linearity over the concentration range of 5 to 1000 ng/mL for teneligliptin and 2.5 to 500 ng/mL for teneligliptin sulfoxide. The developed method is the first fully validated method capable of simultaneous determination of teneligliptin and its active metabolite, teneligliptin sulfoxide in plasma. The suitability of the method was successfully demonstrated in terms of quantification of teneligliptin and teneligliptin sulfoxide pharmacokinetics in plasma samples collected from healthy volunteers. The measurement of plasma metabolite/parent ratio of teneligliptin was feasible by this method.
Development and validation of an LC‐MS/MS method for profiling 39 urinary steroids (estrogens, androgens, corticoids, and progestins)
Authors: Son Hyuck Ho , Yun Wan Soo , Cho Sung‐Hee
Published: October 2019

Abnormal production or metabolism of steroid hormones is responsible for the development of endocrine diseases. Thus, accurate quantification of steroid hormones is needed for both research into clinical conditions and diagnostic and monitoring purposes. An improved analytical method for profiling 39 steroids in urine using LC–MS/MS was developed. As a pre‐treatment procedure prior to LC–tandem mass spectrometry (LC–MS/MS) analysis, hydrolysis using β‐glucuronidase and solid‐phase extraction for purifying the samples were performed. Steroids were separated using Waters ACQUITY BEH C18 column (2.1 × 100 mm, 1.7 μm) and a mobile phase consisting of eluent A (0.01% formic acid and 1 mm ammonium formate in water) and eluent B (0.01% formic acid and 1 mm ammonium formate in methanol) with a gradient program at a flow rate of 0.4 mL/min. Under the optimized method, the linearity of calibration curves was higher than 0.992. The limits of detection at signal‐to‐noise ratio of 3 were 0.03–90 ng/mL. The developed novel LC–MS/MS method can quantitatively profile 39 steroids in a single analytical run. Steroid profiling based on quantitative results could improve the diagnosis and monitoring of hormone‐dependent diseases.
Direct quantification of intact FIM in monkey plasma using a selective chromatography–tandem mass spectrometry method: Application in a pharmacokinetic study
Authors: Dong Shiqi , Zhang Aijie , Gu Yuan , Lu Shuixiu , Teng Lingyan , Wang Rui , Liu Jianfeng , Fan Huirong , Si Duanyun
Published: October 2019

FIM protein, which consists of 155 amino acids, was developed as a novel GLP‐1 analog to reduce blood glucose, and pharmacodynamic results showed that it had a certain effect when used in treating Alzheimer's disease. The molecular weight of FIM is 16,304 Da. In theory, the concentration of FIM in biological samples should be determined by the ligand binding assay method or indirectly quantified using LC–MS/MS instrumentation. However, the above methods are complex and time‐consuming. In this study, we successfully developed a simpler LC–MS/MS method for directly quantifying the intact FIM protein in monkey plasma for the first time. The chromatographic separation of FIM was achieved using an InertSustain Bio C18 column with a mobile phase of acetonitrile containing 0.1% formic acid (A)–water containing 0.1% formic acid (B) at a flow rate of 0.3 ml/min. Good linearity was observed in the concentration range of 5–500 ng/ml (r2 > 0.99). The intra‐ and inter‐day precisions (expressed as relative standard deviation, RSD) of FIM were 2.30–12.8 and 7.30–13.2%, respectively. The intra‐ and inter‐day accuracies (expressed as a relative error, RE) were −12.7–6.55 and − 10.1–0.892%, respectively. This method was successfully applied for a pharmacokinetic study of the FIM protein in four monkeys after subcutaneous administration.
Temperature decrease along hyporheic pathlines in a large river riparian zone
Authors: Faulkner Barton R. , Brooks J. Renée , Keenan Druscilla M. , Forshay Kenneth J.
Published: October 2019

Hyporheic zones contribute to lower temperatures in many rivers, creating a longitudinal heterogeneous array of thermal refuges. In this study, we had the unique opportunity to show temperature reduction along hyporheic zone pathlines in a large river system that contribute to the maintenance of refuges through discharge into off‐channel habitats. Temperature was monitored in a dense network of wells that were located along pathlines in small islands, determined from a calibrated groundwater flow model. Temperature along one 600‐m pathline was reduced about 7° C. Among three islands that were adjacent to the river, the northern two showed exponential decrease in temperature with distance, with fitted thermal Péclet numbers of 2.7 and 6.5, whereas the southern island showed no significant decrease. We suggest that this is due to the higher infiltration rate in the wet season in this larger, more mature island, which suppresses hyporheic flow in the wet season.

Stable isotope sampling showed that values of δ2H were higher in areas where we observed lower temperatures. The overall relationship of δ2H versus temperature was significant with a slope of −0.329. This implies that lower temperatures are associated with water that has had contact with deeper groundwater or that lower temperatures have been affected by local rainfall infiltration or water that has entered the hyporheic zone in winter. These findings are important because they allow estimation of the temperature benefit that may be achieved in similar geomorphic settings, providing implications for riparian restoration.
Mechanisms of Ketone/Imine Hydrogenation Catalyzed by Transition‐Metal Complexes
Authors: Liu Yangqiu , Yue Xin , Luo Chenguang , Zhang Lin , Lei Ming
Published: October 2019

Alcohols and amines are important in pharmaceutical, perfume, and agrochemical industries. Catalytic asymmetric synthesis is one of the major ways to produce chiral alcohols/amines from prochiral ketones/imines via hydrogenation. Meanwhile, the alcohol/amine dehydrogenation with high hydrogen energy density is paid more and more attention as promising hydrogen‐storage media. In this review, we summarize classifications of mechanisms of ketone/imine hydrogenation and alcohol/amine dehydrogenation catalyzed by transition‐metal (TM) complexes, the H2 activation modes, and the nature of asymmetric ketone/imine hydrogenation (AKH/AIH). This will elaborate our understanding on the nature of the TM‐catalyzed ketone/imine hydrogenation and alcohol/amine dehydrogenation reactions.
‘Detachment’ of icefield outlet glaciers: catastrophic thinning and retreat of the Columbia Glacier (Canada)
Authors: Rippin David M. , Sharp Martin , Van Wychen Wesley , Zubot Darryl
Published: October 2019

We present an investigation of changes taking place on the Columbia Glacier, a lake‐terminating outlet of the Columbia Icefield in the Canadian Rockies. The Columbia Icefield is the largest, and one of the most important, ice bodies in the Canadian Rockies. Like other ice masses, it stores water as snow and ice during the winter and releases it during warmer summer months, sustaining river flows and the ecosystems that rely on them. However, the Columbia Glacier and Icefield is shrinking. We use Landsat and Sentinel‐2 imagery to show that the Columbia Glacier has retreated increasingly rapidly in recent years, and suggest that this looks set to continue. Importantly, we identify a previously undocumented process that appears to be playing an important role in the retreat of this glacier. This process involves the ‘detachment’ of the glacier tongue from its accumulation area in the Columbia Icefield. This process is important because the tongue is cut off from the accumulation area and there is no replenishment of ice that melts in the glacier's ablation area by flow from upglacier. As a consequence, for a given rate of ablation, the ice in the tongue will disappear much faster than it would if the local mass loss by melting/calving was partly offset by mass input by glacier flow. Such a change would alter the relationship between rates of surface melting and rates of glacier frontal retreat. We provide evidence that detachment has already occurred elsewhere on the Columbia Icefield and that it is likely to affect other outlet glaciers in the future. Modelling studies forecast this detachment activity, which ultimately results in a smaller ‘perched’ icefield without active outlets. © 2019 John Wiley & Sons, Ltd.
Three‐dimensional reconstruction of fluvial surface sedimentology and topography using personal mobile laser scanning
Authors: Williams Richard David , Lamy Marie‐Lou , Maniatis Georgios , Stott Eilidh
Published: October 2019

High‐resolution quantification of fluvial topography has been enabled by a number of geomatics technologies. Hyperscale surveys with spatial extents of <1 km2 have been widely demonstrated by means of terrestrial laser scanning (TLS) and structure‐from‐motion (SfM) photogrammetry. Recent advances in the development and integration of global navigation satellite system (GNSS), inertial measurement unit (IMU) and lightweight laser scanning technologies are now resulting in the emergence of personal mobile laser scanners (MLS) that have the potential to increase data acquisition and processing rates by one to two orders of magnitude compared to TLS/SfM, and thus challenge the recent dominance of these technologies. This investigation compares a personal MLS survey using a Leica Pegasus Backpack that integrates Velodyne Puck VLP‐16 sensors, and a multi‐station static TLS survey using a Riegl VZ‐1000 scanner, to produce digital elevation models (DEMs) and surface sedimentology maps. The assessment is undertaken on a 500 m long reach of the braided River Feshie. Comparison to 107 independent real‐time kinematic (RTK)‐GNSS check points resulted in similar mean error (ME) and standard deviation error (SDE) for TLS (ME = −0.025 m; SDE = 0.038 m) and personal MLS (ME = −0.014 m; SDE = 0.019 m). Direct cloud‐to‐cloud (C2C) comparison between a sample of TLS and personal MLS observations (2.8 million points) revealed that C2C distances follow a sharply decreasing Burr distribution (a = 2.35, b = 3.19, rate parameter s = 9.53). Empirical relationships between sub‐metre topographic variability and median sediment grain size (10–100 mm) demonstrate that surface roughness from personal MLS can be used to map median grain size. Differences between TLS and personal MLS empirical relationships suggest such relationships are dependent on survey technique. Personal MLS offers distinct logistical advantages over SfM photogrammetry and TLS for particular survey situations and is likely to become a widely applied technique. © 2019 John Wiley & Sons, Ltd.
LINC00673 rs11655237 C>T and susceptibility to Wilms tumor: A five‐center case–control study
Authors: Li Suhong , Lin Ao , Han Dandan , Zhou Haixia , Cheng Jiwen , Zhang Jiao , Fu Wen , Zhuo Zhenjian , He Jing
Published: October 2019

Background

Wilms tumor, a frequently occurring pediatric renal cancer worldwide, originated from the embryonal nephric mesenchyme. However, epidemiological data on the association between LINC00673 polymorphisms and Wilms tumor risk are scant. This case–control study was conducted to investigate the potential role of the LINC00673 rs11655237 C>T polymorphism in the susceptibility to Wilms tumor.

Methods

In the present study, we conducted a genotyping analysis of LINC00673 rs11655237 C>T in 414 cases and 1199 controls recruited from five hospitals in China. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were estimated from multiple logistic regression models to determine the association of LINC00673 rs11655237 C>T polymorphism and Wilms tumor susceptibility.

Results

No significant association between the LINC00673 rs11655237 C>T polymorphism and Wilms tumor risk was observed (CT versus CC: adjusted OR = 0.90, 95% CI = 0.71–1.15; TT versus CC: adjusted OR = 0.86, 95% CI = 0.50–1.49; TT/CT versus CC: adjusted OR = 0.90, 95% CI = 0.71–1.13; and TT versus CC/CT: adjusted OR = 0.89, 95% CI = 0.52–1.53). We also failed to make any remarkable findings for this genotype in the stratification analysis.

Conclusions

In summary, we failed to provide any evidence in favor of the significant susceptibility of rs11655237 C>T polymorphism in LINC00673 to Wilms tumor. These data could be useful for reinforcing our understanding of the potential contribution of LINC00673 rs11655237 C>T to Wilms tumor susceptibility.