bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of Maternal Food Restriction on Heart Proteome in Appropriately Grown and Growth-Restricted Wistar—Rat Offspring
Authors: Zouridis Andreas , Manousopoulou Antigoni , Potiris Anastasios , Sarli Polyxeni-Maria , Aravantinos Leon , Pervanidou Panagiota , Deligeoroglou Efthymios , Garbis Spiros D. , Eleftheriades Makarios
Published: January 2021

Objective: Fetal growth restriction is associated with increased postnatal cardiovascular morbidity. The alterations in heart physiology and structure caused by in utero nutrient deprivation have not been extensively studied. We aim to investigate the impact of maternal food restriction on the cardiac proteome of newborn rats with normal (non-fetal growth-restricted (FGR)) and reduced (FGR) birth weight. Methods: On day 14 of gestation, 10 timed pregnant rats were randomized into two nutritional groups: (a) Standard laboratory diet and (b) 50% global food restriction. Pups born to food-restricted mothers were subdivided, based on birthweight, into fetal growth-restricted (FGR) and non-FGR, while pups born from normally nourished mothers were considered controls. Rat neonates were euthanized immediately after birth and the hearts of 11 randomly selected male offspring (n = 4 FGR, n = 4 non-FGR, n = 3 control group) were analyzed using quantitative proteomics. Results: In total, 7422 proteins were quantified (q < 0.05). Of these, 1175 were differentially expressed in FGR and 231 in non-FGR offspring vs. control with 151 common differentially expressed proteins (DEPs) between the two groups. Bioinformatics analysis of DEPs in FGR vs. control showed decreased integrin and apelin cardiac fibroblast signaling, decreased muscle contraction and glycolysis, and over-representation of a protein network related to embryonic development, and cell death and survival. Conclusion: Our study illustrates the distinct proteomic profile of FGR and non-FGR offspring of food-restricted dams underlying the importance of both prenatal adversities and birth weight in cardiac physiology and development.
Vitamin E Deficiency Disrupts Gene Expression Networks during Zebrafish Development
Authors: Head Brian , Ramsey Stephen A. , Kioussi Chrissa , Tanguay Robyn L. , Traber Maret G.
Published: January 2021

Vitamin E (VitE) is essential for vertebrate embryogenesis, but the mechanisms involved remain unknown. To study embryonic development, we fed zebrafish adults (>55 days) either VitE sufficient (E+) or deficient (E–) diets for >80 days, then the fish were spawned to generate E+ and E– embryos. To evaluate the transcriptional basis of the metabolic and phenotypic outcomes, E+ and E– embryos at 12, 18 and 24 h post-fertilization (hpf) were subjected to gene expression profiling by RNASeq. Hierarchical clustering, over-representation analyses and gene set enrichment analyses were performed with differentially expressed genes. E– embryos experienced overall disruption to gene expression associated with gene transcription, carbohydrate and energy metabolism, intracellular signaling and the formation of embryonic structures. mTOR was apparently a major controller of these changes. Thus, embryonic VitE deficiency results in genetic and transcriptional dysregulation as early as 12 hpf, leading to metabolic dysfunction and ultimately lethal outcomes.
Systematic Review of Nutrition Supplements in Chronic Kidney Diseases: A GRADE Approach
Authors: Lin Pei-Chin , Chou Chu-Lin , Ou Shih-Hsiang , Fang Te-Chao , Chen Jin-Shuen
Published: January 2021

Chronic kidney disease (CKD) is cumulative worldwide and an increasing public health issue. Aside from the widely known protein restriction and medical therapy, less evident is the renal protection of nutrition supplements in CKD patients. This systematic review (SR), using a Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach, aims to summarize and quantify evidence about the prevention effects of vitamin D and analogues, omega-3 polyunsaturated fatty acid (omega-3 PUFA), dietary fiber, coenzyme Q10 (CoQ10), and biotics on CKD progression. This study was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement to examine SRs and/or meta-analysis of clinical controlled trials identified from PubMed, Embase, and the Cochrane Library. Finally, seventeen SRs were included in the qualitative analysis. The beneficial effects of these nutrition supplements in CKD patients mostly seem to be at low to very low evidence on proteinuria, kidney function, and inflammations and did not appear to improve CKD prognosis. The recommendation of nutrition supplements in CKD patients needs to discuss with physicians and consider the benefits over the adverse effects. Longer follow-up of larger randomized trials is necessary to clarify the benefits of nutrition supplements in CKD patients.
Effect of Soil Chemical Properties on the Occurrence and Distribution of Entomopathogenic Fungi in Portuguese Grapevine Fields
Authors: Sharma Lav , Oliveira Irene , Gonçalves Fátima , Raimundo Fernando , Singh Rupesh Kumar , Torres Laura , Marques Guilhermina
Published: January 2021

Entomopathogenic fungi (EPF) contribute to different ecosystem services. However, factors affecting their natural occurrences in soil remain poorly understood. In a previous study, 81 soil samples were subjected to insect baiting using Galleria mellonella and Tenebrio molitor to isolate EPF from Portuguese vine farms. Here, soils yielding any of the four common EPF, i.e., Beauveria bassiana, Purpureocillium lilacinum, Metarhizium robertsii, and Clonostachys rosea f. rosea, were correlated with their chemical properties. Beauveria bassiana was negatively affected by higher available P (p = 0.02), exchangeable K-ions (p = 0.016) and positively affected by higher soil pH_H2O (p = 0.021). High exchangeable K-ions inhibited P. lilacinum (p = 0.011) and promoted C. rosea f. rosea (p = 0.03). Moreover, high available K also suppressed P. lilacinum (p = 0.027). Metarhizium robertsii was inhibited by higher organic matter content (p = 0.009), higher C:N (p = 0.017), total N (p = 0.007), and exchangeable Mg-ions (p = 0.026), and promoted by higher exchangeable Na-ions (p = 0.003). Nonetheless, mean comparisons and principal component analysis suggested that higher soil pH and exchangeable Ca-ions have contrasting effects on EPF occurrences, as they promote B. bassiana and inhibit M. robertsii. Herbicides did not seem to affect EPF presence. Overall, this study is among the first reports on the effects of soil chemistry on EPF other than Metarhizium, and will facilitate biological pest management approaches.
Heat Shock Protein Inhibitor 17-Allyamino-17-Demethoxygeldanamycin, a Potent Inductor of Apoptosis in Human Glioma Tumor Cell Lines, Is a Weak Substrate for ABCB1 and ABCG2 Transporters
Authors: Pastvova Nikola , Dolezel Petr , Mlejnek Petr
Published: January 2021

Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults and has a poor prognosis. Complex genetic alterations and the protective effect of the blood–brain barrier (BBB) have so far hampered effective treatment. Here, we investigated the cytotoxic effects of heat shock protein 90 (HSP90) inhibitors, geldanamycin (GDN) and 17-allylamino-17-demethoxygeldanamycin (17-AAG, tanespimycin), in a panel of glioma tumor cell lines with various genetic alterations. We also assessed the ability of the main drug transporters, ABCB1 and ABCG2, to efflux GDN and 17-AAG. We found that GDN and 17-AAG induced extensive cell death with the morphological and biochemical hallmarks of apoptosis in all studied glioma cell lines at sub-micro-molar and nanomolar concentrations. Moderate efflux efficacy of GDN and 17-AAG mediated by ABCB1 was observed. There was an insignificant and low efflux efficacy of GDN and 17-AAG mediated by ABCG2. Conclusion: GDN and 17-AAG, in particular, exhibited strong proapoptotic effects in glioma tumor cell lines irrespective of genetic alterations. GDN and 17-AAG appeared to be weak substrates of ABCB1 and ABCG2. Therefore, the BBB would compromise their cytotoxic effects only partially. We hypothesize that GBM patients may benefit from 17-AAG either as a single agent or in combination with other drugs.
Think Big, Start Small: How Nanomedicine Could Alleviate the Burden of Rare CNS Diseases
Authors: Faouzi Abdelfattah , Roullin Valérie Gaëlle
Published: January 2021

The complexity and organization of the central nervous system (CNS) is widely modulated by the presence of the blood–brain barrier (BBB) and the blood–cerebrospinal fluid barrier (BCSFB), which both act as biochemical, dynamic obstacles impeding any type of undesirable exogenous exchanges. The disruption of these barriers is usually associated with the development of neuropathologies which can be the consequence of genetic disorders, local antigenic invasions, or autoimmune diseases. These disorders can take the shape of rare CNS-related diseases (other than Alzheimer’s and Parkinson’s) which a exhibit relatively low or moderate prevalence and could be part of a potential line of treatments from current nanotargeted therapies. Indeed, one of the most promising therapeutical alternatives in that field comes from the development of nanotechnologies which can be divided between drug delivery systems and diagnostic tools. Unfortunately, the number of studies dedicated to treating these rare diseases using nanotherapeutics is limited, which is mostly due to a lack of interest from industrial pharmaceutical companies. In the present review, we will provide an overview of some of these rare CNS diseases, discuss the physiopathology of these disorders, shed light on how nanotherapies could be of interest as a credible line of treatment, and finally address the major issues which can hinder the development of efficient therapies in that area.
Compressive Coded Rotating Mirror Camera for High-Speed Imaging
Authors: Matin Amir , Wang Xu
Published: January 2021

We develop a novel compressive coded rotating mirror (CCRM) camera to capture events at high frame rates in passive mode with a compact instrument design at a fraction of the cost compared to other high-speed imaging cameras. Operation of the CCRM camera is based on amplitude optical encoding (grey scale) and a continuous frame sweep across a low-cost detector using a motorized rotating mirror system which can achieve single pixel shift between adjacent frames. Amplitude encoding and continuous frame overlapping enable the CCRM camera to achieve a high number of captured frames and high temporal resolution without making sacrifices in the spatial resolution. Two sets of dynamic scenes have been captured at up to a 120 Kfps frame rate in both monochrome and colored scales in the experimental demonstrations. The obtained heavily compressed data from the experiment are reconstructed using the optimization algorithm under the compressive sensing (CS) paradigm and the highest sequence depth of 1400 captured frames in a single exposure has been achieved with the highest compression ratio of 368 compared to other CS-based high-speed imaging technologies. Under similar conditions the CCRM camera is 700× faster than conventional rotating mirror based imaging devices and could reach a frame rate of up to 20 Gfps.
Design and Fabrication of Large-Size Powersphere for Wireless Energy Transmission via Laser
Authors: He Tiefeng , Pan Guobing , Zhang Libin , Xu Fang , Yang Can , Chan Chi Chiu , Wang Meng , Zheng Guoliang
Published: January 2021

The powersphere is a device used for maximizing the conversion of light in wireless energy transmission via laser. It is a spherical structure made up of thousands of photovoltaic cells. Due to the large dimensions and existence of many holes in the spherical surface, there are some drawbacks in machining, such as limited movement space of the machines, long cycle, low precision, and high cost. In this context, with a powersphere irradiated by the laser as the model, the principle of powersphere is deduced theoretically. It is proven that the illuminance value at any position on the inner wall of the powersphere is equal, and the calculation formula of this value is derived. Based on this theory and the comparative analysis of processing methods and the results of processing experiments, the structure of the powersphere is designed. The experimental processing of the powersphere is carried out by selecting the welding method. Finally, two hemispherical powersphere frames are processed, which are connected by screws to form a ball frame for the installation of photovoltaic cells. The results show that the improved design and fabricating method can process the powersphere quickly, accurately, and economically. A comparative experiment of powersphere and photovoltaic panel was carried out. The experimental results show that the powersphere has the function of light uniformity and repeated use of laser. So, the designed and processed powersphere is consistent with the theoretical analysis.
Habitat Suitability and Establishment Limitations of a Problematic Liana
Authors: Dickinson Christopher C. , Jelesko John G. , Barney Jacob N.
Published: January 2021

The US native liana, poison ivy (Toxicodendron radicans), responsible for contact dermatitis in humans, is a competitive weed with great potential for expansion in disturbed habitats. To facilitate a better understanding of this threat, we sought to evaluate habitat suitability, population demography, and biotic interactions of poison ivy, using a series of complementary field studies in the two habitats where it most commonly occurs—forest interiors and edges. Of the 2500 seeds planted across both habitats, poison ivy initially colonized forest interiors (32% emergence) at a higher rate than edge habitats (16.5% emergence). However, forest interior seedlings were less likely to survive (interior n = 3; edge n = 15), which might be attributed to herbivore pressure when the seedlings were smaller in the less competitive forest interior. Once established, the poison ivy seedlings appeared to be more tolerant of herbivory, except that of large grazers such as deer. The early life stage of seedling emergence, survival, and establishment are critical in poison ivy success, with biotic pressure, especially from plant competition and deer, limiting recruitment. A suitable habitat of this expanding native liana would increase with increasing forest fragmentation, but might be buffered by the expanding deer population.
Extensive Analysis of miRNA Trimming and Tailing Indicates that AGO1 Has a Complex Role in miRNA Turnover
Authors: Giudicatti Axel J. , Tomassi Ariel H. , Manavella Pablo A. , Arce Agustin L.
Published: January 2021

MicroRNAs are small regulatory RNAs involved in several processes in plants ranging from development and stress responses to defense against pathogens. In order to accomplish their molecular functions, miRNAs are methylated and loaded into one ARGONAUTE (AGO) protein, commonly known as AGO1, to stabilize and protect the molecule and to assemble a functional RNA-induced silencing complex (RISC). A specific machinery controls miRNA turnover to ensure the silencing release of targeted-genes in given circumstances. The trimming and tailing of miRNAs are fundamental modifications related to their turnover and, hence, to their action. In order to gain a better understanding of these modifications, we analyzed Arabidopsis thaliana small RNA sequencing data from a diversity of mutants, related to miRNA biogenesis, action, and turnover, and from different cellular fractions and immunoprecipitations. Besides confirming the effects of known players in these pathways, we found increased trimming and tailing in miRNA biogenesis mutants. More importantly, our analysis allowed us to reveal the importance of ARGONAUTE 1 (AGO1) loading, slicing activity, and cellular localization in trimming and tailing of miRNAs.
Identification and Characterization of Wheat Germplasm for Salt Tolerance
Authors: Quan Xiaoyan , Liang Xiaoli , Li Hongmei , Xie Chunjuan , He Wenxing , Qin Yuxiang
Published: January 2021

Salinity is one of the limiting factors of wheat production worldwide. A total of 334 internationally derived wheat genotypes were employed to identify new germplasm resources for salt tolerance breeding. Salt stress caused 39, 49, 58, 55, 21 and 39% reductions in shoot dry weight (SDW), root dry weight (RDW), shoot fresh weight (SFW), root fresh weight (RFW), shoot height (SH) and root length (RL) of wheat, respectively, compared with the control condition at the seedling stage. The wheat genotypes showed a wide genetic and tissue diversity for the determined characteristics in response to salt stress. Finally, 12 wheat genotypes were identified as salt-tolerant through a combination of one-factor (more emphasis on the biomass yield) and multifactor analysis. In general, greater accumulation of osmotic substances, efficient use of soluble sugars, lower Na+/K+ and a higher-efficiency antioxidative system contribute to better growth in the tolerant genotypes under salt stress. In other words, the tolerant genotypes are capable of maintaining stable osmotic potential and ion and redox homeostasis and providing more energy and materials for root growth. The identified genotypes with higher salt tolerance could be useful for developing new salt-tolerant wheat cultivars as well as in further studies to underline the genetic mechanisms of salt tolerance in wheat.
Complete Chloroplast Genome of Abutilon fruticosum: Genome Structure, Comparative and Phylogenetic Analysis
Authors: Alzahrani Dhafer A.
Published: January 2021

Abutilon fruticosum is one of the endemic plants with high medicinal and economic value in Saudi Arabia and belongs to the family Malvaceae. However, the plastome sequence and phylogenetic position have not been reported until this study. In this research, the complete chloroplast genome of A. fruticosum was sequenced and assembled, and comparative and phylogenetic analyses within the Malvaceae family were conducted. The chloroplast genome (cp genome) has a circular and quadripartite structure with a total length of 160,357 bp and contains 114 unique genes (80 protein-coding genes, 30 tRNA genes and 4 rRNA genes). The repeat analyses indicate that all the types of repeats (palindromic, complement, forward and reverse) were present in the genome, with palindromic occurring more frequently. A total number of 212 microsatellites were identified in the plastome, of which the majority are mononucleotides. Comparative analyses with other species of Malvaceae indicate a high level of resemblance in gene content and structural organization and a significant level of variation in the position of genes in single copy and inverted repeat borders. The analyses also reveal variable hotspots in the genomes that can serve as barcodes and tools for inferring phylogenetic relationships in the family: the regions include trnH-psbA, trnK-rps16, psbI-trnS, atpH-atpI, trnT-trnL, matK, ycf1 and ndhH. Phylogenetic analysis indicates that A. fruticosum is closely related to Althaea officinalis, which disagrees with the previous systematic position of the species. This study provides insights into the systematic position of A. fruticosum and valuable resources for further phylogenetic and evolutionary studies of the species and the Malvaceae family to resolve ambiguous issues within the taxa.
Sinbase 2.0: An Updated Database to Study Multi-Omics in Sesamum indicum
Authors: Wang Liwen , Yu Jingyin , Zhang Yanxin , You Jun , Zhang Xiurong , Wang Linhai
Published: January 2021

Sesame is one of the oldest oil crops in the world and is widely grown in the tropical and subtropical areas of Asia, Africa and America. Upon the completion of the sesame reference genome version 1.0, we launched Sinbase 1.0 as an integrated database for genomic and bioinformatics analyses. Recently, an upgraded version (version 2.0) of the genome sequence was released. In addition, large numbers of multi-omics data have been generated on sesame, but a comprehensive database that integrates these resources for the community has been lacking until now. Here, we developed an interactive and comprehensive sesame multi-omics database, Sinbase 2.0, which provides information of the sesame updated genome containing 13 chromosomes, 3 genetic linkage maps, 5 intra- and 6 inter-species comparative genomics, 1 genomic variation analysis, 5 transcriptome data, 1 proteome, 31 functional markers, 175 putative functional genes, and 54 QTLs detected for important agronomic traits. Moreover, Sinbase 2.0 has been enriched with novel user-friendly computational tools. All datasets of Sinbase 2.0 can be downloaded online conveniently. Sinbase 2.0 will be updated regularly with new available sesame multi-omics data and can be accessed freely via Sinbase 2.—Sesame Muti-Omics Database. We expect that Sinbase 2.0, similarly to the previous version, will continue to make a major contribution to advance sesame research towards a better understanding of its biology and genetic improvement, as well as comparative genomics and evolutionary biology.
Antioxidant Potential of Physicochemically Characterized Gracilaria blodgettii Sulfated Polysaccharides
Authors: Khan Bilal Muhammad , Zheng Li-Xin , Khan Wajid , Shah Aftab Ali , Liu Yang , Cheong Kit-Leong
Published: January 2021

Marine rhodophyte polysaccharides have a wide range of described biological properties with nontoxic characteristics, and show great potential in prebiotics and the functional foods industries. However, there is a virtual lack of Gracilaria blodgettii polysaccharides (GBP) profiling and their bioactivities. This study was designed while keeping in view the lack of physical and chemical characterization of GBP. This polysaccharide was also not previously tested for any bioactivities. A linear random coil conformation was observed for GBP, which was found to be a polysaccharide. A significant sulfate (w/w, 9.16%) and 3,6-anhydrogalactose (AHG, w/w, 17.97%) content was found in GBP. The significant difference in its setting (27.33 °C) and melting (64.33 °C) points makes it resistant to increasing heat. This, in turn, points to its utility in industrial scale processing and in enhancing the shelf-life of products under high temperatures. A radical scavenging activity of 19.80%, 25.42% and 8.80% was noted for GBP (3 mg/mL) in 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2’-azino-bis (ABTS) and hydroxyl radical (HO) scavenging assays, respectively. Therefore, the findings suggest that Gracilaria blodgettii polysaccharides display a good antioxidant potential and may have potential applications in the functional food industry.
Multifunctional Structured Platforms: From Patterning of Polymer-Based Films to Their Subsequent Filling with Various Nanomaterials
Authors: Handrea-Dragan Madalina , Botiz Ioan
Published: January 2021

There is an astonishing number of optoelectronic, photonic, biological, sensing, or storage media devices, just to name a few, that rely on a variety of extraordinary periodic surface relief miniaturized patterns fabricated on polymer-covered rigid or flexible substrates. Even more extraordinary is that these surface relief patterns can be further filled, in a more or less ordered fashion, with various functional nanomaterials and thus can lead to the realization of more complex structured architectures. These architectures can serve as multifunctional platforms for the design and the development of a multitude of novel, better performing nanotechnological applications. In this work, we aim to provide an extensive overview on how multifunctional structured platforms can be fabricated by outlining not only the main polymer patterning methodologies but also by emphasizing various deposition methods that can guide different structures of functional nanomaterials into periodic surface relief patterns. Our aim is to provide the readers with a toolbox of the most suitable patterning and deposition methodologies that could be easily identified and further combined when the fabrication of novel structured platforms exhibiting interesting properties is targeted.
Greener, Faster, Stronger: The Benefits of Deep Eutectic Solvents in Polymer and Materials Science
Authors: Nahar Yeasmin , Thickett Stuart C.
Published: January 2021

Deep eutectic solvents (DESs) represent an emergent class of green designer solvents that find numerous applications in different aspects of chemical synthesis. A particularly appealing aspect of DES systems is their simplicity of preparation, combined with inexpensive, readily available starting materials to yield solvents with appealing properties (negligible volatility, non-flammability and high solvation capacity). In the context of polymer science, DES systems not only offer an appealing route towards replacing hazardous volatile organic solvents (VOCs), but can serve multiple roles including those of solvent, monomer and templating agent—so called “polymerizable eutectics.” In this review, we look at DES systems and polymerizable eutectics and their application in polymer materials synthesis, including various mechanisms of polymer formation, hydrogel design, porous monoliths, and molecularly imprinted polymers. We provide a comparative study of these systems alongside traditional synthetic approaches, highlighting not only the benefit of replacing VOCs from the perspective of environmental sustainability, but also the materials advantage with respect to mechanical and thermal properties of the polymers formed.
Development of a Hydropower Turbine Using Seawater from a Fish Farm
Authors: Rakibuzzaman Md , Suh Sang-Ho , Kim Hyoung-Ho , Ryu Youngtae , Kim Kyung Yup
Published: January 2021

Discharge water from fish farms is a clean, renewable, and abundant energy source that has been used to obtain renewable energy via small hydropower plants. Small hydropower plants may be installed at offshore fish farms where suitable water is obtained throughout the year. It is necessary to meet the challenges of developing small hydropower systems, including sustainability and turbine efficiency. The main objective of this study was to investigate the possibility of constructing a small hydropower plant and develop 100 kW class propeller-type turbines in a fish farm with a permanent magnet synchronous generator (PMSG). The turbine was optimized using a computer simulation, and an experiment was conducted to obtain performance data. Simulation results were then validated with experimental results. Results revealed that streamlining the designed shape of the guide vane reduced the flow separation and improved the efficiency of the turbine. Optimizing the shape of the runner vane decreased the flow rate, reducing the water power and increasing the efficiency by about 5.57%. Also, results revealed that tubular or cross-flow turbines could be suitable for use in fish farm power plants, and the generator used should be waterproofed to avoid exposure to seawater.
Gd3+ Complexes Conjugated to Cyclodextrins: Hydroxyl Functions Influence the Relaxation Properties
Authors: Biscotti Anais , Estour François , Sembo-Backonly Berthe-Sandra , Balieu Sébastien , Bosco Michaël , Barbot Cécile , Pallier Agnès , Tóth Éva , Bonnet Célia S. , Gouhier Géraldine
Published: January 2021

In the search for improvement in the properties of gadolinium-based contrast agents, cyclodextrins (CDs) are interesting hydrophilic scaffolds with high molecular weight. The impact of the hydrophilicity of these systems on the MRI efficacy has been studied using five β-CDs substituted with DOTA or TTHA ligands which, respectively, allow for one (q = 1) or no water molecule (q = 0) in the inner coordination sphere of the Gd3+ ion. Original synthetic pathways were developed to immobilize the ligands at C-6 position of various hydroxylated and permethylated β-CDs via an amide bond. To describe the influence of alcohol and ether oxide functions of the CD macrocycle on the relaxation properties of the Gd3+ complexes, 1H Nuclear Magnetic Relaxation Dispersion (NMRD) profiles, and 17O transverse relaxation rates have been measured at various temperatures. The differences observed between the hydroxylated and permethylated β-CDs bearing non-hydrated GdTTHA complexes can be rationalized by a second sphere contribution to the relaxivity in the case of the hydroxylated derivatives, induced by hydrogen-bound water molecules around the hydroxyl groups. In contrast, for the DOTA analogs the exchange rate of the water molecule directly coordinated to the Gd3+ is clearly influenced by the number of hydroxyl groups present on the CD, which in turn influences the relaxivity and gives rise to a very complex behavior of these hydrophilic systems.
Polish Catholic Bishops, Nationalism and Liberal Democracy
Authors: Meyer Resende Madalena , Hennig Anja
Published: January 2021

The alliance of the Polish Catholic Church with the Law and Justice (PiS) government has been widely reported and resulted in significant benefits for the Church. However, beginning in mid-2016, the top church leadership, including the Episcopal Conference, has distanced itself from the government and condemned its use of National Catholicism as legitimation rhetoric for the government’s malpractices in the fields of human rights and democracy. How to account for this behavior? The article proposes two explanations. The first is that the alliance of the PiS with the nationalist wing of the Church, while legitimating its illiberal refugee policy and attacks on democratic institutions of the government, further radicalized the National Catholic faction of the Polish Church and motivated a reaction of the liberal and mainstream conservative prelates. The leaders of the Episcopate, facing an empowered and radical National Catholic faction, pushed back with a doctrinal clarification of Catholic orthodoxy. The second explanatory path considers the transnational influence of Catholicism, in particular of Pope Francis’ intervention in favor of refugee rights as prompting the mainstream bishops to reestablish the Catholic orthodoxy. The article starts by tracing the opposition of the Bishops Conference and liberal prelates to the government’s refugee and autocratizing policies. Second, it describes the dynamics of the Church’s internal polarization during the PiS government. Third, it traces and contextualizes the intervention of Pope Francis during the asylum political crisis (2015–2016). Fourth, it portrays their respective impact: while the Pope’s intervention triggered the bishops’ response, the deepening rifts between liberal and nationalist factions of Polish Catholicism are the ground cause for the reaction.
Quiet Ionospheric D-Region (QIonDR) Model Based on VLF/LF Observations
Authors: Nina Aleksandra , Nico Giovanni , Mitrović Srđan T. , Čadež Vladimir M. , Milošević Ivana R. , Radovanović Milan , Popović Luka Č.
Published: January 2021

The ionospheric D-region affects propagation of electromagnetic waves including ground-based signals and satellite signals during its intensive disturbances. Consequently, the modeling of electromagnetic propagation in the D-region is important in many technological domains. One of sources of uncertainty in the modeling of the disturbed D-region is the poor knowledge of its parameters in the quiet state at the considered location and time period. We present the Quiet Ionospheric D-Region (QIonDR) model based on data collected in the ionospheric D-region remote sensing by very low/low frequency (VLF/LF) signals and the Long-Wave Propagation Capability (LWPC) numerical model. The QIonDR model provides both Wait’s parameters and the electron density in the D-region area of interest at a given daytime interval. The proposed model consists of two steps. In the first step, Wait’s parameters are modeled during the quiet midday periods as a function of the daily sunspot number, related to the long-term variations during solar cycle, and the seasonal parameter, providing the seasonal variations. In the second step, the output of the first step is used to model Wait’s parameters during the whole daytime. The proposed model is applied to VLF data acquired in Serbia and related to the DHO and ICV signals emitted in Germany and Italy, respectively. As a result, the proposed methodology provides a numerical tool to model the daytime Wait’s parameters over the middle and low latitudes and an analytical expression valid over a part of Europe for midday parameters.
Validation and Comparison of Physical Models for Soil Salinity Mapping over an Arid Landscape Using Spectral Reflectance Measurements and Landsat-OLI Data
Authors: Al-Ali Z. M. , Bannari A. , Rhinane H. , El-Battay A. , Shahid S. A. , Hameid N.
Published: January 2021

The present study focuses on the validation and comparison of eight different physical models for soil salinity mapping in an arid landscape using two independent Landsat-Operational Land Imager (OLI) datasets: simulated and image data. The examined and compared models were previously developed for different semi-arid and arid geographic regions around the world, i.e., Latino-America, the Middle East, North and East Africa and Asia. These models integrate different spectral bands and unlike mathematical functions in their conceptualization. To achieve the objectives of the study, four main steps were completed. For simulated data, a field survey was organized, and 100 soil samples were collected with various degrees of salinity levels. The bidirectional reflectance factor was measured above each soil sample in a goniometric laboratory using an analytical spectral device (ASD) FieldSpec-4 Hi-Res spectroradiometer. These measurements were resampled and convolved in the solar-reflective bands of the Operational Land Imager (OLI) sensor using a radiative transfer code and the relative spectral response profiles characterizing the filters of the OLI sensor. Then, they were converted in terms of the considered models. Moreover, the OLI image acquired simultaneously with the field survey was radiometrically preprocessed, and the models were implemented to derive soil salinity maps. The laboratory analyses were performed to derive electrical conductivity (EC-Lab) from each soil sample for validation and comparison purposes. These steps were undertaken between predicted salinity (EC-Predicted) and the measured ground truth (EC-Lab) in the same way for simulated and image data using regression analysis (p ˂ 0.05), coefficient of determination (R2), and root mean square error (RMSE). Moreover, the derived maps were visually interpreted and validated by comparison with observations from the field visit, ancillary data (soil, geology, geomorphology and water table maps) and soil laboratory analyses. Regardless of data sources (simulated or image) or the validation mode, the results obtained show that the predictive models based on visible- and near-infrared (VNIR) bands and vegetation indices are inadequate for soil salinity prediction in an arid landscape due to serious signals confusion between the salt crust and soil optical properties in these spectral bands. The statistical tests revealed insignificant fits (R2 ≤ 0.41) with very high prediction errors (RMSE ≥ 0.65), while the model based on the second-order polynomial function and integrating the shortwave infrared (SWIR) bands provided the results of best fit, with the field observations (EC-Lab), yielding an R2 of 0.97 and a low overall RMSE of 0.13. These findings were corroborated by visual interpretation of derived maps and their validation by comparison with the ground truthing.
Video-Based System for Automatic Measurement of Barbell Velocity in Back Squat
Authors: Pueo Basilio , Lopez Jose J. , Mossi Jose M. , Colomer Adrian , Jimenez-Olmedo Jose M.
Published: January 2021

Velocity-based training is a contemporary method used by sports coaches to prescribe the optimal loading based on the velocity of movement of a load lifted. The most employed and accurate instruments to monitor velocity are linear position transducers. Alternatively, smartphone apps compute mean velocity after each execution by manual on-screen digitizing, introducing human error. In this paper, a video-based instrument delivering unattended, real-time measures of barbell velocity with a smartphone high-speed camera has been developed. A custom image-processing algorithm allows for the detection of reference points of a multipower machine to autocalibrate and automatically track barbell markers to give real-time kinematic-derived parameters. Validity and reliability were studied by comparing the simultaneous measurement of 160 repetitions of back squat lifts executed by 20 athletes with the proposed instrument and a validated linear position transducer, used as a criterion. The video system produced practically identical range, velocity, force, and power outcomes to the criterion with low and proportional systematic bias and random errors. Our results suggest that the developed video system is a valid, reliable, and trustworthy instrument for measuring velocity and derived variables accurately with practical implications for use by coaches and practitioners.
Research on the Prediction of Green Plum Acidity Based on Improved XGBoost
Authors: Liu Yang , Wang Honghong , Fei Yeqi , Liu Ying , Shen Luxiang , Zhuang Zilong , Zhang Xiao
Published: January 2021

The acidity of green plum has an important influence on the fruit’s deep processing. Traditional physical and chemical analysis methods for green plum acidity detection are destructive, time-consuming, and unable to achieve online detection. In response, a rapid and non-destructive detection method based on hyperspectral imaging technology was studied in this paper. Research on prediction performance comparisons between supervised learning methods and unsupervised learning methods is currently popular. To further improve the accuracy of component prediction, a new hyperspectral imaging system was developed, and the kernel principle component analysis—linear discriminant analysis—extreme gradient boosting algorithm (KPCA-LDA-XGB) model was proposed to predict the acidity of green plum. The KPCA-LDA-XGB model is a supervised learning model combined with the extreme gradient boosting algorithm (XGBoost), kernel principal component analysis (KPCA), and linear discriminant analysis (LDA). The experimental results proved that the KPCA-LDA-XGB model offers good acidity predictions for green plum, with a correlation coefficient (R) of 0.829 and a root mean squared error (RMSE) of 0.107 for the prediction set. Compared with the basic XGBoost model, the KPCA-LDA-XGB model showed a 79.4% increase in R and a 31.2% decrease in RMSE. The use of linear, radial basis function (RBF), and polynomial (Poly) kernel functions were also compared and analyzed in this paper to further optimize the KPCA-LDA-XGB model.
Remaining Useful Life (RUL) Prediction of Equipment in Production Lines Using Artificial Neural Networks
Authors: Kang Ziqiu , Catal Cagatay , Tekinerdogan Bedir
Published: January 2021

Predictive maintenance of production lines is important to early detect possible defects and thus identify and apply the required maintenance activities to avoid possible breakdowns. An important concern in predictive maintenance is the prediction of remaining useful life (RUL), which is an estimate of the number of remaining years that a component in a production line is estimated to be able to function in accordance with its intended purpose before warranting replacement. In this study, we propose a novel machine learning-based approach for automating the prediction of the failure of equipment in continuous production lines. The proposed model applies normalization and principle component analysis during the pre-processing stage, utilizes interpolation, uses grid search for parameter optimization, and is built with multilayer perceptron neural network (MLP) machine learning algorithm. We have evaluated the approach using a case study research to predict the RUL of engines on NASA turbo engine datasets. Experimental results demonstrate that the performance of our proposed model is effective in predicting the RUL of turbo engines and likewise substantially enhances predictive maintenance results.
Multifunctional Cement Mortars Enhanced with Graphene Nanoplatelets and Carbon Nanotubes
Authors: Dalla Panagiota T. , Tragazikis Ilias K. , Trakakis George , Galiotis Costas , Dassios Konstantinos G. , Matikas Theodore E.
Published: January 2021

Recent findings have brought forward the potential of carbon nano-species, especially nanotubes and graphene, to impart exceptional multifunctional potential to cement, offering simultaneous enhancement of mechanical, fracture mechanical and electrical properties. While available knowledge on the topic is still limited, there is a complete absence of direct comparisons of the potential of the nano-species to improve strength and toughness and provide multifunctionality to the mortars. The study offers a comprehensive overview of these potentials, for mortars modified with pure graphene nanoplatelets and carbon nanotubes at consistent, directly comparable, concentrations up to 1.2 wt.%. Testing included flexure under pure bending moments, axial compression, electrical resistivity measurements and fracture tests under three point bending configuration; the latter were also independently assessed by acoustic emission. Differences in documented properties and optimal concentrations associated with improved mechanical performance were directly compared and rationalized in terms of nanospecies morphology. Dramatic, statistically consistent improvements in fracture behavior, up to 10-fold of control values, were documented for specific nanofiller concentrations, indicating an excellent potential of the material system for contemporary smart construction applications. An exceptionally favorable comparison of acoustic emission and fracture energy data confirmed that the non-destructive technique can independently assess the fracture performance of mortars with exceptional precision.
Discussion Protocol for Alleviating Epistemic Injustice: The Case of Community Rehabilitation Interaction and Female Substance Abusers
Authors: Auvinen Petra , Parviainen Jaana , Lahikainen Lauri , Palukka Hannele
Published: January 2021

Substance-abusing women are vulnerable to specific kinds of epistemic injustice, including stigmatization and discrimination. This article examines the development of the epistemic agency of female substance abusers by asking: How does the use of a formal discussion protocol in community rehabilitation interaction alleviate epistemic injustice and strengthen the epistemic agency of substance abusers? The data were collected in a Finnish rehabilitation center by videotaping six group discussions between social workers, peer support workers, and rehabilitation clients with substance abuse problems. Of these data, one recorded group discussion between four female participants—two rehabilitation clients, a peer support worker, and a social adviser—was used in this paper. Using conversational analysis, the findings indicate that, through the collaborative activities of sharing experiential knowledge about substance abuse and discussing the experiences of abuse in the rehabilitation interaction, substance abusers can develop novel ways to strengthen their epistemic agency by enhanced self-awareness. The discussion protocol is an epistemic tool that professionals and clients can learn to use in ethically and epistemologically successful ways in interaction. The use of a discussion protocol is an example of social professionals’ clinical knowledge of intensifying collaboration and sharing experiential knowledge in community rehabilitation and other substance abuse services.
Sustainable Biocultural Heritage Management and Communication: The Case of Digital Narrative for UNESCO Marine World Heritage of Outstanding Universal Value
Authors: Kenterelidou Clio , Galatsopoulou Fani
Published: January 2021

The paper addresses sustainability, heritage, management, and communication from UNESCO’s Marine World Heritage (MWH) perspective, analyzing its digital narrative footprint through social media. It aims to understand how MWH is conceptualized, managed, and communicated and whether it is framed with sustainability and biocultural values facilitating interactivity, engagement, and multimodal knowledge. Hence, a content analysis of the Instagram accounts of the MWH of Outstanding Universal Value (OUV) sites and protected areas has been conducted. The study included evidence from their Instagram profile, posts, features, and reactions. The findings indicated the dearth of a management and communication strategy being shared among and across UNESCO’s MWH of OUV sites and protected areas, capturing the “lifeworld” and the “voice” of the marine heritage as unified. They also revealed that nature and human, and biological and socio-ecological ecosystems of MWH of OUV sites and protected areas are not interlinked in marine heritage management and communication featuring the whole and the entirety of the marine heritage site ecosystem. The lack of this expansion of meaning and engagement does not facilitate the shift of the route in the marine-scape, from discovery and being listed as World Heritage to human-nature interaction, diversity, dynamicity, and ocean literacy. The study contributes to setting the ground rules for strengthening marine heritage management and communication in light of the United Nations Sustainable Development Goals (SDGs) and the Ocean Literacy Decade (2021–2030).
Transport Poverty with Special Reference to Sustainability: A Systematic Review of the Literature
Authors: Pérez-Peña María del Carmen , Jiménez-García Mercedes , Ruiz-Chico José , Peña-Sánchez Antonio Rafael
Published: January 2021

The aim of this work is to analyse the state of the art of scientific research related to transport poverty with special reference to sustainability and to identify new research needs. To this end, a methodology has been used in line with the objective set out, choosing the systematic review of the literature as the most suitable method. The results show that transport poverty is an under-exploited issue and is not well articulated by researchers, and there are great differences between the different areas of knowledge studied. The subjects related to health and medicine have more publications, almost 58%, with the rest distributed among 11 different subjects. Of the works analysed, only 26.69% refer to the topic of sustainability, and therefore this is a branch which is little studied in the literature in this field. Another relevant finding is that all the articles analysed highlight the vulnerability and inequality of the groups affected by transport poverty, with the elderly being the least studied in the research work.