bluuebunny/crossref_metadata_2025 huggingface dataset:
Telehealth Satisfaction in Patients Receiving Virtual Atrial Fibrillation Care: Quantitative Exploratory Study
Authors: Rush Kathy L , Burton Lindsay , Seaton Cherisse L , Loewen Peter , O'Connor Brian P , Moroz Lana , Corman Kendra , Smith Mindy A , Andrade Jason G
Published: September 2023

Background

Telehealth can optimize access to specialty care for patients with atrial fibrillation (AF). Virtual AF care, however, may not fit with the complex needs of patients with AF.

Objective

This study aims to explore the correlation among attitudes toward health care technologies, self-efficacy, and telehealth satisfaction as part of the future planning of virtual AF clinic care.

Methods

Patients with AF older than 18 years from an urban-based, highly specialized AF clinic who had an upcoming telehealth visit were invited to participate in a web-based survey. The survey asked about demographic characteristics; use of technology; general, computer, and health care technology self-efficacy (HTSE) and health care technology attitudes, using a validated 30-item tool; and telehealth satisfaction questionnaire using a validated 14-item questionnaire. Data were analyzed with descriptive statistics, correlational analyses, and linear regression modeling.

Results

Participants (n=195 of 579 invited, for a 34% response rate) were primarily older, male, and White, had postsecondary schooling or more, and had high self-reported overall and mental health ratings. A variety of technologies were used in their daily lives and for health care, with the majority of technologies comprising desktop and laptop computers, smartphones, and tablets. Self-efficacy and telehealth satisfaction questionnaire scores were high overall, with male participants having higher general self-efficacy, computer self-efficacy, HTSE, and technology attitude scores. After controlling for age and sex, only HTSE was significantly related to individuals’ attitudes toward health care technology. Both general self-efficacy and attitude toward health care technology were positively related to telehealth satisfaction.

Conclusions

Consistent with a previous study, only HTSE significantly influenced attitudes toward health care technology. This finding confirms that, in this regard, self-efficacy is not a general perception but is domain specific. Considering participants’ predominant use of the telephone for virtual care, it follows that general self-efficacy and attitude toward health care technology were significant contributors to telehealth satisfaction. Given our patients’ frequent use of technology and high computer self-efficacy and HTSE scores, the use of video for telehealth appointments could be supported.
Exploring Semantic Nuances in English Synonyms through Multimodal Analysis
Authors: Yu Lei
Published: September 2023

In foreign language education, distinguishing English synonyms has long posed a formidable challenge due to context-dependent usage, often leading ESL learners to perplexity. Learners commonly attempt differentiation based on subtle emotional nuances, evaluative connotations, and semantic intensity. This study employs the Corpus of Contemporary American English (COCA), along with image and audio data, to scrutinize the semantic nuances of the synonyms: “reveal”, “disclose”, and “expose”. The investigation unveils the subsequent pivotal discoveries: “Reveal” exhibits greater prevalence relative to “disclose” and “expose”, frequently associating with abstract nouns, whereas the latter two demonstrate a proclivity for specific terms. These terms display collocational variations, signifying distinctive contextual preferences. Through the integration of image and audio data, the study further underscores the subtle distinctions among these synonyms on both visual and auditory levels. This research contributes a novel methodology for a nuanced comprehension of these synonyms, allowing for a multidimensional understanding facilitated by the amalgamation of multimodal data. It provides educators with a more enriched pedagogical approach to assist learners in employing these synonyms with greater precision.
Relación entre la motivación y las competencias emprendedoras en empresarias
Authors: Miranda Sánchez Jennifer Darvelia , Sandoval Caraveo María Del Carmen , Berttolini Díaz Gilda María
Published: September 2023

La motivación y las competencias empresariales pueden considerarse relacionadas, ya que un individuo buscará poner en práctica sus mejores habilidades para desarrollar y sostener un emprendimiento. Con base en lo anterior, se presentan los resultados de un estudio en el que participaron 212 mujeres emprendedoras de Tabasco, México, utilizando un instrumento para medir sus motivaciones y competencias emprendedoras. Donde se identificó la priorización como principal competencia emprendedora y la búsqueda de autonomía como principal motivador para emprender. Además, por medio de un modelo de ecuaciones estructurales, se identificó que existe una relación positiva entre ambas variables, aunque ésta no es significativa. También se identificó que la seguridad económica no es un factor que explique el constructo de motivación para esta población. Ante esto, se propone el desarrollo de investigaciones que propongan constructos enfocados en las mujeres y su participación empresarial, considerando sus características particulares y contextuales.
Análisis factorial del estilo de toma de decisiones en la efectividad de la estrategia organizacional
Authors: Montenegro-Velandia Wilson , Díaz-Montenegro Sharloth Xiomara
Published: September 2023

El objetivo de este artículo es examinar empíricamente el estilo de toma de decisiones y su relación con la efectividad en la estrategia organizacional en el contexto de las empresas latinoamericanas. Se aplicó un análisis factorial exploratorio y confirmatorio. Recolectamos información de 230 tomadores de decisiones en empresas de diferente sector económico y de diferente tamaño. La investigación ha demostrado que el estilo de toma de decisiones, determinado por los tipos de pensamiento y la gestión emocional de las personas, tiene una relación directa con la efectividad de la estrategia organizacional. El estudio identifica competencias que conforman los factores determinantes del estilo de toma de decisiones. Además, se proporciona un marco respecto al alcance que las organizaciones tienen de desarrollar estrategias efectivas basadas en las capacidades dinámicas del personal.
Tipos de celos en una comunidad universitaria
Authors: Jimenez Villasana Juana Marisela , Barrios Gómez Edna Marcela
Published: September 2023

La temática curricular constituye una de las problemáticas de mayor incidencia en la práctica educativa. Dominar este tema y mostrarlo se ha convertido en una de las ocupaciones más importante para la docencia. La práctica educativa es un eje recurrente de las investigaciones actuales, principalmente situado en el manejo que se tiene desde la concepción del currículo. A partir de los planteamientos que hace la UNESCO en 1998 centrando el proceso enseñanza-aprendizaje en el estudiante, el aula es la vitrina donde habrán de observarse los cambios que demanda la actual reforma educativa, cuyo enfoque está basado en el desarrollo de competencias. La nueva exigencia que surge a partir de la autonomía escolar y el currículum descentralizado, demanda la aplicación de este nuevo enfoque curricular, que si bien parece aún no ser considerado como uso prioritario en los modelos educativos de las Instituciones de Educación Superior, es pertinente su revisión para encontrar una respuesta a los nuevos desarrollos socio-culturales.
Un acercamiento a la historia de la educación de la mujer mexicana
Authors: Córdoba Navarro Mariana
Published: September 2023

La revolución del conocimiento en los últimos tres milenios, ha sido posible gracias a la integración de la mujer en el proceso de enseñanza – aprendizaje – evaluación y asertividad de manera gradual, a través de diversos momentos históricos, y continúa innovando diversas metodologías y propuestas de cambio que contribuyen al desarrollo del intelecto humano. Históricamente, el siglo XIX fue significativo en los procesos de fortalecimiento del desarrollo educativo de las mujeres y este artículo trata de esbozar el curso histórico de la educación de las mujeres mexicanas, a través de las revistas para mujeres.
Artificial Intelligence Based Online Examination Proctoring System
Authors: G N Niharika , Nayak Dr. Sankhya N
Published: September 2023

Abstract: Distance and online learning, often known as e-learning, has emerged as the new norm in training and education in light of recent technological advancements, thanks to a number of benefits like accessibility, cost, efficiency, and usability. Even though the online educational system offers advantages over the traditional educational system, preventing cheating and other improper behavior of students during classes and exams poses substantial difficulties. The 'Artificial Intelligence based Online Examination proctoring system' project offers a solution to the issues with online and distance education. The system makes use of movement detection, face recognition, and other biometric approaches to flag the student fraud during exams. As soon as the cheating or other irregularities are detected by the students, the system signals the manual proctor and also records these instances as evidence for subsequent monitoring. As a result, online exams can be administered effectively with fewer or no manual proctors present, which is more practical and affordable
Campus Connect: An Online Learning Platform
Authors: Deore Shubham Nandkishor , Gaikwad Dhammadeep , Joshi Yash , Chougule Suhas , Shahabade Mr. Ramesh
Published: September 2023

Abstract: Through this project, we aim to solve the problem that has arisen due to the pandemic - how can traditional methods of learning be integrated with e-learning? We are driven to create an application that seamlessly merges the two methods that the education system currently relies on, allowing both students and teachers to benefit. Students using this app will be able to access their attendance records, course status, test performances, and online study resources. Teachers will be provided with an interface through which they can upload attendance records, provide recorded lectures or notes, and interact with students to solve their doubts. They can also communicate with parents to address any concerns they may have regarding their child. Additionally, teachers will be allowed to share notices on the app, which will notify students and allow them to schedule tests. Parents using this application can track their ward's performance.
Object Fetching UAV using Autonomous Flight and Object Detection Algorithms
Authors: Harkare Aarya , Jaiswal Dr. Rupesh C.
Published: September 2023

Abstract: Autonomous UAVs (Unmanned Aerial Vehicles) are being used in various applications around the world like surveillance and aerial security, construction, agriculture, delivery, etc. These applications require heavy duty UAVs with high payload capacity and long battery life. The aim of this project is to use the principles of autonomous flight and object detection for indoor autonomous flight with the target to fetch and deliver lightweight objects with minimum energy and time consumption to create a viable prototype for indoor applications like delivering objects to bedridden patients, smart home applications, warehouse management and more.
Computer Interaction Using Hand Gestures
Authors: K Mr. Vishwanath M , D Prajwal S , M Karthik K , Shankar Achyuth J , Mogali Suraj U
Published: September 2023

Abstract: Computer interaction using hand gestures is theprocess of automatically recognizing hand gestures that enablespeople to interact with the computer. Usually, interaction with a computer is done using input devices like keyboards, mice, etc., and the need to develop contactless human-computer interaction methods is the most desired feature during these pandemic days. Gesture recognition is a significant step towardsachieving contactless new types of human-computer interaction. A deep learning approach, convolution neural network, is used to recognize the hand gestures and mapped operation to the respective gesture is performed.
Violencia obstétrica en el proceso del aborto
Authors: Moreira Michelle Araújo , Souza Amanda Santana de , Oliveira Pedro Moreira , Souza Mariana Xavier de , Araújo Junior José Carlos de , Ribeiro Polliana Santos
Published: September 2023

Objetivo: Analisar as práticas assistenciais de saúde no processo do abortamento tipificadas como violência obstétrica. Metodologia: Estudo qualitativo e descritivo, realizado em um hospital público no Brasil com 15 profissionais de saúde de nível médio e superior. Os dados foram coletados presencialmente, através de um roteiro de entrevista semiestruturada. O perfil foi analisado pela estatística descritiva simples e as questões abertas pela técnica de conteúdo temática proposta por Bardin. Resultados: Evidenciou-se que as práticas que denotam violência obstétrica relacionam-se a alocação das mulheres em processo de abortamento no mesmo ambiente que gestantes e puérperas e ao emitirem juízos de valor no momento da assistência às mulheres. Conclusão: Há necessidade de educação permanente para que as/os profissionais possam assistir de maneira humanizada e qualificada.
ATUAÇÃO E IMPORTÂNCIA DA PSICO-ONCOLOGIA
Authors: Assunção Cleaide Ataíde Lima
Published: September 2023

Cancer, as well as its medical treatment, leads to a wide variety of physical and psychosocial problems and, in general, cancer patients are not prepared to deal with the psychological and emotional burden that accompanies the diagnosis of cancer and which only increases with age. time if not treated properly. Thus, psycho-oncology has emerged as an interdisciplinary field with the aim of addressing these issues and providing support for these patients. In this context, this study aims to describe the importance of psycho-oncology in the treatment of cancer patients. It was found that, when the individual is diagnosed with an oncological disease, only physical care cannot be offered, as it is a multifactorial disease, where emotions play a fundamental role. It is concluded, therefore, that the need for psycho-oncology is undeniable, especially in addressing the psychological responses to cancer, such as the initial trauma, denial, anxiety, depression, fear, anger and other manifestations during the various treatment phases.
Asymptotic diffusion analysis of the retrial queuing system with feedback and batch Poisson arrival
Authors: Nazarov Anatoly A. , Rozhkova Svetlana V. , Titarenko Ekaterina Yu.
Published: September 2023

The mathematical model of the retrial queuing system \(M^{[n]}/M/1\) with feedback and batch Poisson arrival is constructed. Customers arrive in groups. If the server is free, one of the arriving customers starts his service, the rest join the orbit. The retrial and service times are exponentially distributed. The customer whose service is completed leaves the system, or reservice, or goes to the orbit. The method of asymptotic diffusion analysis is proposed for finding the probability distribution of the number of customers in orbit. The asymptotic condition is growing average waiting time in orbit. The accuracy of the diffusion approximation is obtained.
A consulta de enfermagem no pré-natal por equipes de Saúde da Família em uma cidade mineira
Authors: Dias Ernandes Gonçalves , Santos Milla Cristy Braga , Sousa Pedro Henrique de , Campos Lyliane Martins , Caldeira Maiza Barbosa
Published: September 2023

The objective of the study was to investigate nursing consultations processing in prenatal care in Family Health Strategies in a city in Minas Gerais. This is a descriptive, qualitative study carried out with eight nurses with three to five years of experience in Primary Care. Data were collected between August and September 2021, through an interview, analyzed using Thematic Analysis. It was observed that the consultation is subsidized by guidelines from the Ministry of Health and its own instrument. The registration is done on the medical record, in the pregnant women's booklet, and in digital spreadsheets. Recurrent nursing problems were low adherence to prenatal care, lack of family support, and unbalanced nutrition. Work overload and lack of nursing protocols hinder nurses' work. It is concluded that the Systematization of Nursing Care is partially applied; however, identifying nursing problems during consultations is essential for comprehensive care.
A Capacitive Mismatch Calibration Method for SAR ADCs Based on TDC
Authors: Shen Qing , Jiang mei , Chen Junxian , He Xinhui , Wang Xin
Published: September 2023

The capacitance mismatch problem limits the accuracy improvement of
high-precision SAR ADCs (Successive Approximation Register
Analog-to-Digital Converters). To address the capacitance array mismatch
in SAR ADCs, this paper proposes a novel capacitor calibration scheme
based on the Time-to-Digital Converter (TDC). This scheme achieves
calibration accuracy as high as 0.01\% and can be
flexibly designed to meet the accuracy requirements of SAR ADCs.
Simulation results indicate that the capacitance mismatch issue of a
redundant capacitor 13-bit SAR ADC can be completely eliminated, and the
effective number of bits (ENOB) can approach the ideal value of 13.18
bits. Additionally, the analog component of this scheme utilizes four
inverter chains, two D flip-flops, and four counters, without requiring
a large area for auxiliary calibration capacitors.
Nonresilience curve
Authors: Wang Cao
Published: September 2023

Resilience assessment is a widely-used tool to evaluate the ability of
an object (e.g., an individual structure, or a system consisting of
multiple interacting structures) to withstand, recover from, and adapt
to disruptive events. This paper proposes a novel concept of
“nonresilience curve”, which measures the nonresilience (complement of
resilience) of an object of interest conditional on a specific hazard
intensity. It is by nature an extension of the well-established
fragility curves, integrating the multiple damage states of a
post-hazard object. The applicability of the proposed nonresilience
curve to individual structures and systems (including series systems,
parallel systems, and more general & complicated systems) has been
demonstrated in this paper. It is also preliminarily shown that the
shape of the cumulative distribution function of a lognormal
distribution is suitable to approximate the nonresilience curve, if only
limited data points associated with the target nonresilience curve are
available. Since the nonresilience curve is a function of the hazard
intensity measure, one can estimate the nonresilience of an object in a
fully probabilistic manner by additionally taking into account the
uncertainty associated with the intensity measure. The proposed
nonresilience curve can be further extended to formulate nonresilience
surface, which is a joint function of both the intensity measure and the
available resource that supports the post-hazard recovery process. The
nonresilience curve is promising to be adopted in engineering practice
for resilience assessment and resilience-based design of civil
structures and infrastructures.
Orientation-dependent mechanical responses in Mo-Re alloys evaluated via micro-pillars
Authors: Xu Hailong , huang Li , Zhang Wen , Liang Jing , Gao Xuan , Li Jianfeng
Published: September 2023

Textures in Molybdenum-Rhenium alloys are inevitable during thermal
fabrication. [110] and [100] are common orientations in
Molybdenum-Rhenium alloys and effect mechanical responses. However,
orientation dependence of mechanical responses in Molybdenum-Rhenium
alloys is not quite clear yet. To clarity this problem, micro-pillar
compression tests are conducted in grains with orientation [100] and
[110] separately. Orientation-dependent compressive properties are
found in Mo-14Re and Mo-42Re, but are not found in Mo and Mo-5Re, which
may be attributed to activated muiti-slip planes as increased Re. Solid
solution effect of Re not only rely on orientations, but also on Re
content. Softening effect occurs in both [100] and [110] Mo-5Re.
while, strong strengthening effect happens in [110] Mo-14Re and
Mo-42Re. Our research clarifies that Mo-Re alloys with [110]
orientation / texture could be preferred to obtain good strengthening
effect.
Beyond bleomycin-induced pulmonary toxicity, its male reproductive toxicity remains unanswered 50 years after its approval
Authors: Almeida Ana Lobo de , Sousa Mário , Sá Rosália
Published: September 2023

Aim: Cancer treatment long-term complications for men include testicular
dysfunction and possible infertility. Nonetheless, the evidence for this
risk for various chemotherapies is insufficient. This is the case with
bleomycin, which, aside from its well-studied lung toxicity, has
received little research attention for its effect on male reproduction.
This systematic review sought evidence for the effects of
bleomycin-cancer treatment on testicular function and fertility.
Methods: PubMed and Web of Science were searched using specific search
terms, and seven animal studies met all inclusion criteria and provided
an analysis of bleomycin gonadotoxicity. Results: Overall, the results
suggest that bleomycin is gonadotoxic. It has the same effect on the
nuclear DNA integrity of rodent sperm as it does on cancer cells.
Bleomycin-induced changes in rodent testis histopathology are most
noticeable at seminiferous tubule structure level. Bleomycin also
significantly decreases rodents´ seminal conventional parameters and
testosterone levels, the latter of which is consistent with increased
induced degeneration of Leydig cells. Seminiferous tubule necrosis and
alterations in tunica albuginea thickness in rodent testis are signs of
a bleomycin-induced inflammatory process similar to the pulmonary one.
Conclusion: More research, particularly human research, is required to
provide strong evidence on how bleomycin affects human testicular
function, including hormone function; and whether is gonadotoxic,
whether it has a transient or permanent effect; how it may affect
offspring; and how it can be reduced. Despite this, the current findings
have important implications for clinicians in counseling patients about
fertility risk and guiding requirements for fertility preservation
strategies.
Cargo sorting into, and the interactive effects of, membrane vesicles: knowledge pool and gaps in fungal phytopathogens
Authors: E Thabiso Motaung , M Francinah Ratsoma , C Quentin Santana , D Brenda Wingfield , T Emma Steenkamp
Published: September 2023

Organisms from all kingdoms of life release membrane vesicles, which are
tiny and spherical structures made of a lipid bilayer. Membrane vesicles
carry out a number of functions, such as forming new cell membranes,
removing waste products from the cell, and transporting lipids and other
substances from parent to recipient cells. The payloads often contained
in the vesicles are sorted via the endosomal sorting complex required
for transport (ESCRT) pathway in a stepwise manner. Alterations to this
endomembrane system reduces formation of vesicles and aberrant endosomal
compartments. Furthermore, in pathogenic fungi, the deletion of ESCRT
genes negatively effects virulence and growth, suggesting the ESCRT
pathway has links to disease. However, only a few fungal species have to
date been evaluated for the ESCRT pathway. In this review, we evaluate
recent developments in the ESCRT pathway of fungi that infect plant
hosts and its role in pathogenesis. This will provide an overview of
EV-mediated cell-cell communication during host-pathogen interactions.
Phostensin carries a novel Eps 15 homology domain-containing protein 1 (EHD1) and EHD4-binding motif to regulate endocytic recycling
Authors: Huang Hsien-Bin , Huang Kuang-Yung , Yu Hui-Chun , Lu Ming-Chi , Huang Hsien-Yu , Shen Jyun-Jie , Lin Chia-Ying , Chung Pei-Rong , Tsai Hsiao-Kuei , Shen Ya-Ting , Zhou Si-Ru , Fan Chih-Wei , Wang Chia-Lin , Lai Ning-Sheng , Lin Ta-Hsien
Published: September 2023

Phostensin (PTS) encoded by KIAA1949 is a scaffold protein. It
can bind to protein phosphatase 1 (PP1), F-actin, Eps 15 homology
domain-containing protein 1 (EHD1) and EHD4. PTS contains both
PP1-binding and actin-binding motifs. Most EHD-binding proteins contain
a consensus motif, Asn-Pro-Phe (NPF) motif, which interacts with the
C-terminal EH domain of EHD proteins. Nevertheless, the NPF motif is
absent in PTS. The binding motif for PTS to associate with EHD1 (or
EHD4) remains unknown. Here, we used structure-function, far western
blotting and GST pull-down assays to investigate this issue and
identified that PTS-α binds to EHD1 (or EHD4) through the region of
residues 60-80 which contains a consensus motif,
ILV(X) (L/V)RL
S. This novel motif was also found in the vacuolar
protein sorting 35 (vps35) of retromer, an EHD1-associating complex and
regulating retrograde trafficking, Replacement of
ILV(X) (L/V)RL
S with AAA(X)
(L/V)RL S or with
ILV(X) AEA A
significantly reduces the binding efficiency of PTS-α to either EHD1 or
EHD4. Overexpression of the PTS-β in 293T cells attenuated the endocytic
trafficking of transferrin. However, this attenuation of transferrin in
endocytic trafficking was disrupted when 293T cells overexpressed the
mutant PTS-β with a defective EHD-binding motif, suggesting that PTS-β
can regulate the endocytic recycling via associating with EHD1 or EHD4.
IUCN Global Standard for Nature-based Solutions: first edition (Thai version)
Authors:   IUCN, International Union for Conservation of Nature
Published: September 2023

The IUCN Global Standard for Nature-based Solutions lists the Criteria and Indicators, as adopted by the 98th Meeting of the IUCN Council in 2020.
The possibilities of using the inhibitors of matrix metalloproteinases for keratoplasty
Authors: Sirotkina K. V. , Chentsova E. V.
Published: September 2023

Introduction. The review is devoted to the actual problem of treating patients with keratolysis. The role of matrix metalloproteinases in the pathogenesis of cornea and corneal graft melting is discussed as well as the practical experience of using synthetic metalloproteinase inhibitors in various branches of medicine and in ophthalmology, in particular. In the field of eye diseases, the search for effective methods for the treatment of corneal injuries of various origins, as well as its post-transplant complications, has been underway for a long time. Recent studies have shown that local imbalance of matrix metalloproteinases and their inhibitors system, as well as the immune system status, may play the main role in the outcome of urgent keratoplasty, and the use of synthetic metalloproteinase inhibitors can significantly improve the biological result of the donor cornea transplant. The role of platelets in the regulation of the proteolytic system has not been fully studied. However, some literature data on the platelet-associated inhibitor of metalloproteinases and the use of platelet-rich plasma to correct the collagenolytic activity of enzymes are of great interest to ophthalmologists, due to therapeutic efficacy and simple method of producing its production the autologous platelet-rich plasma.The present brief literature review covers the pathogenesis and clinical features of keratolysis, factors which can affect the outcome of urgent keratoplasty, describes the features of matrix metalloproteinases, their inhibitors, and the plateletrich plasma as a potential endogenous source of a tissue inhibitor of matrix metalloproteinases.Aim. To evaluate the possibility of using inhibitors of matrix metalloproteinases for keratoplasty based on a literature review.Material and methods. To write the review article, we have made the search in the homeland eLibrary.RU database and in the PubMed resource database to select the articles on the topic published in the period from 1985 to 2022.
Features of the myocardial infarction course in convalescents of the new coronavirus infection COVID-19
Authors: Muradyan N. A. , Kuzmina I. M. , Gvindzhiliya T. R. , Balanyan V. M. , Popugaev K. A.
Published: September 2023

Acute myocardial injury is one of the possible complications of the new coronavirus infection COVID-19 and can be diagnosed both in the acute phase of the infection, and also after stabilization or clinical improvement of the patient's condition. This review is devoted to the actual problem of the acute myocardial infarction development during the period of COVID-19 convalescence. The pathophysiological mechanisms of acute myocardial infarction during recovery from COVID-19 are diverse. The key role belongs to the state of hypercoagulation and the systemic inflammatory response, which can provoke destabilization and rupture of unstable atherosclerotic cardiac plaques. Type 2 acute myocardial infarction is most often diagnosed in COVID-19 convalescents against the background of intact coronary arteries. In this case, acute myocardial infarction develops due to an imbalance between increased myocardial oxygen demand (increased levels of cytokines in the blood, hypercatecholaminemia, hyperthermia and tachycardia) and a decrease in oxygen supply to cardiomyocytes due to hypoxemia and hypotension. Subclinical myocardial injury may be present despite normal coronary arteries on angiography and intact left ventricular ejection fraction. There is no clear relationship between the development of acute myocardial infarction during the period of COVID-19 convalescence and the severity of the infection, the time from the initial diagnosis, and the presence of traditional risk factors for cardiovascular diseases in the patient. Cardiac complaints in COVID-19 convalescents are often interpreted as a post-COVID syndrome, especially given the absence of a history of coronary heart disease in many patients, which can lead to late diagnosis. Further study of the features of acute myocardial infarction during the period of COVID-19 convalescence is needed.
Phenomenon of Demikhov. At N.V. Sklifosovsky Institute (1960–1986). V.P. Demikhov and his experiments in the field of organ transplantation in 1968–1973
Authors: Glyantsev S. P.
Published: September 2023

The article analyzes the experimental studies of V.P. Demikhov conducted by him in 1968-1973, by studying the content of his report on the work done during this period of time and presented at the Meeting of the Academic Council of N.V. Sklifosovsky Institute in July 1973 for the re-election for the position of the Head of the Organ Transplantation Laboratory for a new 5-year term. It follows from the analyzed document that the extent of the research made by V.P. Demikhov and his staff significantly exceeded the data that were presented in the Institute's reporting documents for 1973, in the Research Plans for 1974, and the plans for implementing the research results in healthcare practice in 1974. The Table that illustrated the report indicated that in 1968–1973 V.P. Demikhov conducted more than 485 different experiments, including transplantation of vital organs, experiments on perfusion of isolated organs, resuscitation of cadaveric hearts, and heterogeneous blood transfusion. He actively collaborated with surgeons from many clinical institutions in Moscow (Institute of Tuberculosis, S.P. Botkin Hospital, Hospitals of the Moscow Military District) and other cities of the country (Frunze, Tyumen), conducting joint experimental and clinical studies with them. However, attempts to introduce the methods developed by him into clinical practice were futile. Of all his achievements in different years, the method of upper limb reimplantation was successfully applied in clinic in 1971 by Professor B.D. Komarov.
The EU Settled Status (Wales) data linkage project: Initial findings relating to health and education
Authors: Lloyd-Williams Ffion , Drinkwater Stephen , Curds Matt
Published: September 2023

ObjectivesFunded by ADR UK (ESRC) from 2020 to 2023, the project aims to anonymously link European Union Settlement Scheme (EUSS) data with other data already held within the SAIL Databank, based at Swansea University, and produce a research-ready dataset that can be used by researchers to obtain policy-relevant findings.

MethodUsing a range of de-identified data in the SAIL Databank, a control group of British citizens in Wales has been matched with EU citizens with similar characteristics using the Census 2011 as a spine to identify country of birth. The SQL coding programme is used to link Census data with several other datasets in the SAIL Databank relating to health, with a focus on mental health, education and employment. The R software package is used for statistical analysis to produce comparisons between the groups and performing significance tests of these comparisons (e.g. Mann Whitney).

ResultsInitial findings indicate small but statistically significant differences in school attendance between British pupils in Wales and pupils from EU14 and EU8 countries and similar differences in school attainment between British pupils in Wales and pupils from EU14 and EU8 countries. Further analysis has been conducted to explore differences between pupils from EU14 and EU8 countries. Census data are also linked to GP attendance data to explore differences in mental health related consultations and referrals for British citizens in Wales and citizens from EU countries and differences between citizens from EU14 and EU8 countries. Detailed findings from this linking of datasets and analysis will be presented.

ConclusionLinking data in this way helps to gain a better understanding of the experiences and outcomes of EU citizens in Wales, generating better evidence to help inform policies and services that address the needs of this population and offers a dataset of great interest to academics.
Walking the line: Does crossing a high stakes exam threshold matter for labour market outcomes?
Authors: Anderson Oliver
Published: September 2023

ObjectivesThis paper offers new insight into the link between success in high stakes exams and subsequent education and labour market outcomes. It is the first study to look holistically at the impact of crossing an important high stakes threshold on both academic and vocational education choices and ultimately labour market outcomes.

MethodIt does so by comparing those either side of a formerly important threshold in the English education system at the end of compulsory schooling (achieving five general certificate of secondary education A* to C passes) which was commonly regarded as the minimum benchmark for continuing into post-compulsory education.

ResultsI find that crossing this threshold led to an 6.3-6.7 percentage point increase in the proportion of men and women (respectively) going on to take academic qualifications, with little change in the proportion taking vocational qualifications, leading to a net increase in those staying on after compulsory schooling. Women's daily earnings in 2017-18 (11-13 years after leaving compulsory schooling) were 3.1 percentage points higher for those just crossing the threshold, but men's early labour market outcomes were unchanged.

ConclusionThe results for men can be explained by low returns to academic qualifications for marginal learners. The findings for women do not disappear after accounting for subsequent education choices, suggesting that crossing the threshold may play a signalling role for employers as well as education institutions.
Validation of a dynamic method of measuring households and populations from primary care Electronic Health Records: Cross-sectional comparison with Office for National Statistics Census 2021 estimates
Authors: Wilk Marta , Harper Gill , Firman Nicola , Dibben Chris , Fry Rich , Dezateux Carol
Published: September 2023

ObjectivesWe have developed a dynamic method for identifying household members from Electronic Health Records (EHR). We compared the 2021 Census estimates of household number and demography with similar estimates derived from primary care EHRs on the Census date using primary care EHRs for the population of north east London (NEL).

MethodWe included 2,115,017 patients registered with a general practitioner on the 2021 Census date in NEL and assigned households from encrypted Unique Property Reference Numbers. We compared household number and size by Local Authority (LA), Middle Layer Super Output Area (MSOA) and area’s Index of Multiple Deprivation quintiles (IMDq) to Office for National Statistics (ONS) 2021 Census estimates and by LA to ONS Admin Based Housing Stock (ABHS) 2020 estimates. We assessed differences in EHR and Census 2021 populations by sex, age, LA, MSOA and IMDq. Sensitivity analyses will exclude those without a recent recorded clinical encounter.

ResultsEHR population estimates (2,115,017) were 116,346 (5.8%) higher than Census estimates (1,998,671), higher among men (9.2%) than women (2.5%) in almost all age groups, especially men aged 30-50 years and higher in the most (8.7%), than in the least (2.5%) deprived IMDq. EHR household estimates (660,789) were 68,047 (9.3%) lower than Census estimates (728,836), and 19,719 (3.1%) higher than ABHS occupied addresses (641,070). EHR household size estimates were 15.6%, 29.2%,12.5% and 8.4% lower for household sizes 1,2 3 and 4, and 13.3%, 42.1%, 82.1% and 195.8% higher for household sizes 5, 6,7 and 8 respectively when compared to Census estimates. EHR population and household estimates were respectively 5-10% higher and 5-11% lower for almost all NEL local authorities.

ConclusionEHR- and Census-derived population and household estimates differ, mainly in the prevalence of larger households. While data were extracted on the same date, person-level validation was not possible. Differences may reflect deregistration delay in EHR when changing residence. Analyses based on clinical encounters recency may identify registered patients who are no longer residents.
The impact of record source on multimorbidity measurement and mortality associations: A comparison study
Authors: MacRae Clare
Published: September 2023

ObjectivesMeasurement of multimorbidity is important; the impact of choice of record source on multimorbidity measurement is uncertain. We compared estimated prevalence of multimorbidity and associations with mortality using different record sources.

MethodCross-sectional study of SAIL Databank data including 2,340,027 individuals of all ages living in Wales on 01 January 2019. Comparison of multimorbidity and LTC prevalence using diagnosis codes from primary care (PC), hospital inpatient (HI), and linked PC-HI records, and associations with 12-month mortality were calculated.

ResultsMultimorbidity was more prevalent (32.2% versus 16.4%), included a younger population (62.5 years versus 66.8 years) with more women (54.2% versus 52.6%), and was more strongly associated with mortality (adjusted odds ratio 7.93 [95%CI 7.62-8.25] versus 4.70 [95%CI 4.55-4.85] in people with ≥ 4 LTCs) using linked PC-HI than HI records. Prevalence of LTCs using PC versus HI records was significantly higher in 37/47 and significantly lower in 10/47. Averaging all LTCs, the ratio of PC/linked PC-HI records was higher than HI/linked PC-HI records (84.7% [interquartile range, IQR 76.7 to 90.4] versus 49.0 [IQR 31.9 to 83.6]). Measures of concordance between PC and HI records varied widely across LTCs and the Kappa statistic, a comparison of percentage agreement and chance alone, was slight in five, fair in 13, moderate in 17, and substantial in 12 LTCs, and lowest in mental and behavioural disorders.

ConclusionUsing linked PC-HI records provides higher estimated prevalence of multimorbidity with higher proportions of certain populations and higher association with mortality. Use of single record sources will underestimate the prevalence of many important conditions, especially mental and behavioural disorders.
School performance trajectories and young adult offending: Findings from a national administrative data linkage, United Kingdom
Authors: Wickersham Alice , Cornish Rosie , Scott Stephen , Downs Johnny
Published: September 2023

ObjectivesCriminal offending and re-offending comes at a significant social and economic cost. Offending prevention therefore presents a high priority policy area. Low educational attainment is a known risk factor for offending, but little is understood about how changes in school performance over time might be associated with offending.

MethodsWe investigated this in a large sample of n~4.3 million pupils using an administrative data linkage between two routinely-collected national datasets: the National Pupil Database (NPD) and the Police National Computer (PNC). First, we conducted growth mixture modelling using NPD data over three statutory testing years (School Years 2, 6 and 11). We then investigated the association between membership of these trajectories and subsequent conviction or caution for any criminal offence between Year 11 and age 21.

ResultsWe derived five school performance trajectories: (1) Average Consistent (n=3,497,167, 81.0%), (2) Average Increasing (n=66,383, 1.5%), (3) Average Declining (n=373,117, 8.6%), (4) Low Increasing (n=98,805, 2.3%), and (5) Low Consistent (n=281,964, 6.5%). The Average Declining group had the highest proportion of individuals who went on to be convicted or cautioned for any first offence up to age 21 (9.8%), followed by the Low Consistent (8.5%), Low Increasing (5.6%), Average Consistent (4.2%) and Average Increasing (1.5%) groups. Furthermore, as the number of offending days between Year 11 and age 21 increased (indicating repeat offending), the likelihood of having been in the Average Declining or Low Consistent groups also increased. We will also present findings from multilevel models accounting for school clustering, different offence types, and interactions.

ConclusionTentatively, findings suggest that changes in school performance could help to identify pupils who are struggling and at increased risk of criminal justice involvement, and therefore might be in need of additional support.
AD|ARC (Administrative Data | Agricultural Research Collection): Linking individual, household and farm business data for agricultural research – Challenges of linking agricultural datasets with individual-level records
Authors: Morrison-Rees Sian , Webster Nicholas , Caskie Paul
Published: September 2023

ObjectivesTo create an anonymised research-ready data resource of farm households in the UK to generate evidence to support policy development, implementation and evaluation; improve understanding of farm family socio-economic characteristics; and assist stakeholders interested in understanding the health and well-being, resilience and prosperity and spatial properties of farming communities.

MethodsThe ADARC research-ready data resource is being created in each nation of the UK. Each core dataset links agricultural datasets with individual- and household-level population data from the Census 2011. The farm business data is drawn from a number of sources (the Inter Departmental Business Register, EU Farm Structure Survey 2010 and Rural Payments data), which presented many data preparation challenges when linking to the Census of Population. Each core dataset will be linked to the health and education data available for that nation. Where possible, the ADARC datasets have been harmonised to allow federated querying across the UK.

ResultsThe ADARC core datasets are complete in Wales and near completion in England and Scotland. Work is also well advanced in Northern Ireland. To the best of our knowledge, these are the first datasets linking agricultural data to individual- and household-level data at a population level. We will report the challenges experienced in linking farm business data with data at the household and individual level. This will include a description of the data preparation steps, the challenges encountered and solutions utilised at each stage of building this complex dataset from numerous, very different ‘parent’ datasets.

The structure and content of the core datasets will be presented as well as the potential benefits to researchers investigating the individual, household and community dimensions of agricultural research.

ConclusionAgriculture is currently facing a range of challenges with little known about the impact on farmers and farming households. ADARC introduces a new, powerful and versatile resource that will help inform debate and potentially lead to better outcomes on a range of issues relevant to farmers and farming communities.
Linking of the 2021 Census to massive linked administrative data to understand coverage and quality
Authors: Plachta Josie , Collyer Sarah
Published: September 2023

The Office for National Statistics has built a vast, composite dataset for population statistics by linking data from health, education, and employment sources, known as the Demographic Index (DI). It attempts to contain a record ‘cluster’ for each person in England and Wales. To understand the coverage and quality of the DI, it has been linked to the 2021 Census to a high standard, enabling review of those captured incorrectly: and over- and undercoverage.

Massive data techniques were used to apply deterministic, probabilistic, and associative methods. High quality was achieved by applying clerical matching methods to cases that could not be confirmed by automatic techniques. Due to resource limitations, only a subsample was linked to this high standard. The resulting links were flagged to indicate cases where the DI had correctly captured persons or had made errors. Errors included capturing persons at the wrong address, accidently splitting a person’s records across two clusters, or incorrectly capturing two persons in the same cluster. Unlinked records were flagged as under-coverage (census) or over-coverage (DI).

The 2021 Census was linked to the DI with an estimated precision of 99.4%-99.7% and recall of 99.1%-99.7%. This exceptional quality allows ONS analysts to use this dataset with high confidence in analysing the quality of the DI and its impact on statistics. In general, DI under-coverage was low, with 0.9% of Census records in the subsample not present on the DI. However, DI over-coverage was much higher, with 29.5% of DI records in the subsample not present on the census. 2.3% of census persons in the subsample had been incorrectly split across multiple clusters, and 0.3% had been merged into a cluster with multiple other persons.

The ONS successfully linked the 2021 Census to the DI to a high quality. The linkage suggests that the DI captures most of the current population correctly but captures many persons that are not. These insights must be considered by any users of the data.