bluuebunny/crossref_metadata_2025 huggingface dataset:
Implementation of the Papua Province Special Autonomy Policy in a Public Policy Perspective
Authors: Mussad Muhammad
Published: July 2022

Abstract The prolonged battle in Papua has resulted in various multifaceted setbacks, most of which are ignored by the international community. The people of Papua faced a loss that hit them very hard. The purpose of this piece is to examine how certain autonomy policies have been put into practice in Papua Province. The methodology that is used is qualitative. The study that was conducted, which was found in a variety of books and journals, was utilized to compile the data that was employed. The image that can be discovered in this article illustrates the fact that the implementation of the special autonomy has not been carried out in an effective and efficient manner. There is still a long way to go before indicators of the performance of public services and the settlement of conflicts can be considered perfect. In order for the government to arrive at the conclusion that the policy of granting special autonomy cannot necessarily be implemented in a pragmatic manner, it must take humanist approaches that promote a sense of humanity. Keywords: Implementation, Policy, Special Autonomy, Public Policy. AbstrakPertempuran berkepanjangan di Papua telah menghasilkan berbagai kemunduran multifaset, yang sebagian besar diabaikan oleh dunia internasional. Orang Papua menghadapi kerugian yang sangat memukul mereka. Tujuan dari bagian ini adalah untuk mengkaji bagaimana kebijakan otonomi tertentu telah dipraktekkan di Provinsi Papua. Metodologi yang digunakan adalah kualitatif. Kajian yang dilakukan, yang ditemukan dalam berbagai buku dan jurnal, digunakan untuk mengumpulkan data yang digunakan. Gambaran yang dapat ditemukan dalam artikel ini menggambarkan fakta bahwa pelaksanaan otonomi khusus belum dilaksanakan secara efektif dan efisien. Jalan masih panjang sebelum indikator kinerja pelayanan publik dan penyelesaian konflik dapat dikatakan sempurna. Agar pemerintah sampai pada kesimpulan bahwa kebijakan pemberian otonomi khusus tidak serta merta dapat dilaksanakan secara pragmatis, harus dilakukan pendekatan humanis yang mengedepankan rasa kemanusiaan. Kata kunci: Implementasi, Kebijakan, Otonomi Khusus, Kebijakan Publik.
Bruno Latour como portavoz de la configuración ontológica del mundo
Authors: Ramos Zincke Claudio
Published: July 2022

El artículo destaca la nueva mirada ontológica que aporta Latour, la cual se expresa en Nunca fuimos modernos. En esta obra, él recupera los híbridos negados por la modernidad, rechazando sus grandes separaciones como aquella entre mundo natural y sociedad humana. El artículo sostiene que, en las últimas décadas, esa hibridez negada se ha hecho crecientemente más visible, en algunos casos de forma intimidante, como a través de la amenaza de destrucción ecológica, en otros casos de forma más ambivalente, como respecto a la expansión de la digitalización de la actividad humana. Todos estos fenómenos respaldan las afirmaciones de Latour y, al mismo tiempo, se ven iluminados por su enfoque. Por otra parte, el artículo sostiene que la obra de Latour cuestiona muy centralmente a la sociología predominante. Esta ha sido reacia a atender a esa hibridez del mundo moderno, apelando en cambio a grandes entidades estructurales como sustento de sus explicaciones o ha convertido la realidad social en procesos puramente discursivos. Latour apunta a las cadenas de prácticas, tecnologías, materialidades y otros elementos que la cons- tituyen. De tal modo, este autor provee una nueva cartografía que reordena ontológicamente el mundo, aportando un enfoque innovador para indagarlo.
A Tilt in the Dark Matter Halo of the Galaxy
Authors: Han Jiwon Jesse , Naidu Rohan P. , Conroy Charlie , Bonaca Ana , Zaritsky Dennis , Caldwell Nelson , Cargile Phillip , Johnson Benjamin D. , Chandra Vedant , Speagle 沈 Joshua S. 佳 士 , Ting 丁 Yuan-Sen 源 森 , Woody Turner
Published: July 2022

Recent observations of the stellar halo have uncovered the debris of an ancient merger, Gaia–Sausage–Enceladus (GSE), estimated to have occurred ≳8 Gyr ago. Follow-up studies have associated GSE with a large-scale tilt in the stellar halo that links two well-known stellar overdensities in diagonally opposing octants of the Galaxy (the Hercules–Aquila Cloud and Virgo Overdensity; HAC and VOD). In this paper, we study the plausibility of such unmixed merger debris persisting over several gigayears in the Galactic halo. We employ the simulated stellar halo from Naidu et al., which reproduces several key properties of the merger remnant, including the large-scale tilt. By integrating the orbits of these simulated stellar halo particles, we show that adoption of a spherical halo potential results in rapid phase mixing of the asymmetry. However, adopting a tilted halo potential preserves the initial asymmetry in the stellar halo for many gigayears. The asymmetry is preserved even when a realistic growing disk is added to the potential. These results suggest that HAC and VOD are long-lived structures that are associated with GSE and that the dark matter halo of the Galaxy is tilted with respect to the disk and aligned in the direction of HAC–VOD. Such halo–disk misalignment is common in modern cosmological simulations. Lastly, we study the relationship between the local and global stellar halo in light of a tilted global halo comprised of highly radial orbits. We find that the local halo offers a dynamically biased view of the global halo due to its displacement from the Galactic center.
The Optical Two- and Three-dimensional Fundamental Plane Correlations for Nearly 180 Gamma-Ray Burst Afterglows with Swift/UVOT, RATIR, and the Subaru Telescope
Authors: Dainotti M. G. , Young S. , Li L. , Levine D. , Kalinowski K. K. , Kann D. A. , Tran B. , Zambrano-Tapia L. , Zambrano-Tapia A. , Cenko S. B. , Fuentes M. , Sánchez-Vázquez E. G. , Oates S. R. , Fraija N. , Becerra R. L. , Watson A. M. , Butler N. R. , González J. J. , Kutyrev A. S. , Lee W. H. , Prochaska J. X. , Ramirez-Ruiz E. , Richer M. G. , Zola S.
Published: July 2022

Gamma-ray bursts (GRBs) are fascinating events due to their panchromatic nature. We study optical plateaus in GRB afterglows via an extended search into archival data. We comprehensively analyze all published GRBs with known redshifts and optical plateaus observed by many ground-based telescopes (e.g., Subaru Telescope, RATIR) around the world and several space-based observatories such as the Neil Gehrels Swift Observatory. We fit 500 optical light curves, showing the existence of the plateau in 179 cases. This sample is 75% larger than the previous one, and it is the largest compilation so far of optical plateaus. We discover the 3D fundamental plane relation at optical wavelengths using this sample. This correlation is between the rest-frame time at the end of the plateau emission,

T

opt

*

, its optical luminosity, L
opt, and the peak in the optical prompt emission, L
peak,opt, thus resembling the three-dimensional (3D) X-ray fundamental plane (the so-called 3D Dainotti relation). We correct our sample for redshift evolution and selection effects, discovering that this correlation is indeed intrinsic to GRB physics. We investigate the rest-frame end-time distributions in X-rays and optical (

T

opt

*

,

T

X

*

), and conclude that the plateau is achromatic only when selection biases are not considered. We also investigate if the 3D optical correlation may be a new discriminant between optical GRB classes and find that there is no significant separation between the classes compared to the Gold sample plane after correcting for evolution.
How much do Romanian medical students know about research ethics? A survey
Authors: Andronic Octavian , Bolocan Alexandra , Păduraru Dan Nicolae , Ion Daniel , Musat Florentina
Published: July 2022

Background: Although scientific research in Romania has continued to expand over the past 20 years, it is unclear how prepared the country’s students are to be involved in research and to publish the results of their work.

Objectives: To assess Romanian medical students’ level of knowledge about research integrity and research ethics.

Methods: A cross-sectional survey of 187 medical students (of which 70% were women) from Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, was performed between September 2017 and June 2018. The survey consisted of self-evaluation with respect to three aspects, namely knowledge of research in general, that of research integrity, and that of publication integrity. The self-evaluation was followed by a set of 17 questions that tested the respondent’s knowledge.

Results: On average, the proportion of correct answers was 34% (range, 12%–65%). Whereas those who had assigned low grades to themselves (a score below 5) fared poorly (fewer correct answers) in the test that followed, those who rated themselves highly (a score of 5 or higher) did not fare as well as they were expected to. The majority of respondents (83%) were willing to learn more about research integrity through courses, workshops, training programmes, etc.

Conclusion: The respondents showed a low level of knowledge related to both research integrity and current standards of reporting scientific research. This lacuna demonstrates the need to train students at the beginning of their academic life because more and more of them, both undergraduate and postgraduate, are likely to be involved in scientific research.
Optimal blood pressure target in the elderly: rationale and design of the HOW to Optimize eLDerly systolic Blood Pressure (HOWOLD-BP) trial
Authors: Lee Dong-Hwa , Lee Ju-Hee , Kim So Young , Lee Hae-Young , Choi Jung-Yeon , Hong Youjin , Park Sue K. , Ryu Dong Ryeol , Yang Dong Heon , Hwang Seok-Jae , Choi Jung Hyun , Kim Kye Hun , Lee Sun Hwa , Joo Seung Jae , Park Jae-Hyeong , Kim Sang-Hyun , Kim Hack-Lyong , Kim Kwang-il , Cho Myeong-Chan
Published: July 2022

Background/Aims: The optimal systolic blood pressure (SBP) goal for elderly patients with hypertension, especially to reduce cardiovascular disease (CVD) incidence and improve outcome, is unclear. This study aimed to evaluate the beneficial effects of intensive treatment for hypertension on the incidence of CVD in elderly Korean patients.Methods: The HOW to Optimize eLDerly systolic Blood Pressure (HOWOLD-BP) trial is a multicenter, parallel-design, open-label, randomized controlled trial designed to evaluate whether intensive treatment (SBP ≤ 130 mmHg) will provide more benefits in lowering the incidence and mortality associated with CVD than standard treatment (SBP ≤ 140 mmHg) in elderly patients with hypertension aged ≥ 65 years. For this study, eleven university hospitals in Korea will enroll approximately 3,176 elderly patients with hypertension between 2019 and 2022. Patients will be requested to visit the clinic every 4 months for the first year and every 6 months thereafter for 36 months. Parameters, including clinic and home blood pressure, anthropometric and laboratory findings, and frailty assessments, will be collected according to the standardized protocol. The primary outcome is a composite of CVD (acute coronary syndrome, stroke, and heart failure) incidence and cardiovascular deaths.Results: As of December 2021, 1,655 participants had been enrolled in the study, including 831 patients in the standard group and 824 patients in the intensive group.Conclusions: The HOWOLD-BP trial is the first study performed in Korea to evaluate the beneficial effects of intensive blood pressure treatment on CVD in elderly patients with hypertension. The results of this study will help clarify the appropriate target SBP for this population.
Vagus Nerve Stimulation for Treatment-Resistant Depression: Current Status of This Novel Treatment
Authors: Conway Charles R. , Hristidis Vasilis C. , Gott Britt M. , Willie Jon
Published: July 2022

Patients with treatment-resistant or difficult-to-treat major depression (TRD/DTD) have limited proven treatment options. Vagus nerve stimulation (VNS), chronic stimulation of the left cervical vagus nerve using an implantable pulse generator, has been demonstrated in numerous clinical trials to effectively treat TRD/DTD. In this review, seminal and ongoing vagus nerve stimulation trials are summarized and compared, and critical clinical findings are discussed.

[
Psychiatr Ann.
2022;52(7):272–282.]
Statistical convergence of new type difference sequences with Caputo fractional derivative
Authors: Karakaş Abdulkadir
Published: July 2022

In this study, we discuss the idea of difference operators $ \Delta _{p}^{\alpha }, \Delta _{p}^{\left(\alpha \right) } $ $ \left(\alpha \in \mathbb{R}\right) $ and examine some properties of these operators. We also describe the concepts of ordered statistical convergence and lacunary statistical by using the $ \Delta _{p}^{\alpha } $-difference operator. We examine some features of these sequence spaces and present some inclusion theorems. We obtain the Caputo fractional derivative in this work.
An efficient relaxed shift-splitting preconditioner for a class of complex symmetric indefinite linear systems
Authors: Li Qian , Yuan Qianqian , Chen Jianhua
Published: July 2022

In this work, by introducing a scalar matrix $ \alpha I $, we transform the complex symmetric indefinite linear systems $ (W+i T)x = b $ into a block two-by-two complex equations equivalently, and propose an efficient relaxed shift-splitting (ERSS) preconditioner. By adopting the relaxation technique, the ERSS preconditioner is not only a computational advantage but also closer to the original two-by-two of complex coefficient matrix. The eigenvalue distributions of the preconditioned matrix are analysed. An efficient and practical formula for computing the parameter value $ \alpha $ is also derived by computing the Frobenius norm of symmetric indefinite matrix $ T $. Numerical examples on a few model problems are illustrated to verify the performances of the ERSS preconditioner.
Using Open-Source Software for Business, Urban, and Other Applications of Deep Neural Networks, Machine Learning, and Data Analytics Tools
Authors: Segall Richard S. , Sankarasubbu Vidhya
Published: July 2022

This article provides an overview with examples of what Neural Networks (NN), Machine Learning (ML), and Artificial Intelligence (AI) and Data Analytics are, and with their applications in business, urban and biomedical situations. The characteristics of 29 types of neural networks are provided including their distinctive graphical illustrations. A survey of current open-source software (OSS) for neural networks, neural network software available for free trial download for limited time use, open-source software (OSS) for Machine Learning (ML), and open-source software (OSS) for Data Analytics tools are provided. Characteristics of Artificial Intelligence (AI) technologies for Machine Learning available as open-source are discussed. Illustrations of applications of Neural Networks, Machine Learning, and Artificial Intelligence are presented as used in the daily operations of a large international-based software company for optimal configuration of their Helix Data Capacity system and other.
Does High-Effort Thinking Prevent One From Sharing Misinformation?
Authors: Alka V.  , Pothiyil Dan Isaac , Ravindran Syam K.
Published: July 2022

Misinformation has remained challenging in spite of all the innovative strategies and existing regulations. Globally, it has continued to lay a strong grip on society by influencing people’s worldview. Even though the spread of misinformation in the virtual world was majorly investigated as a result of the uncontrollable nature of the medium itself, this study has aimed at understanding the relationship between the need for effortful thinking with the likeliness to share and believe in misinformation by young adults. The study employed a cross sectional design and recruited 384 participants between the ages of 18 and 25 and utilised the Need for cognition scale NCS-6 by Coelho, Hanel, & Wolf, 2018, to measure effortful thinking and a checklist to measure likeliness to share social media messages.The results revealed that high effort thinking in individuals prevents further sharing of misinformation on social media. This study also shed light on the difference in effortful thinking on the basis of religion, education, years of social media usage and location of residence.
Multi-Contextual Analysis of Internet Security Perception and Behavior
Authors: Gyaisey Alfred Paa , Owusu Acheampong
Published: July 2022

Perception has been found to influence thought patterns and human behavior in other academic spheres. However, the impact of perception on technology adoption and use in the field of Information Systems is virtually nonexistent. This study sought to examine the internet security perception of internet users and consequential effect on their online behavior. The study used language (French vs English), as a differentiation tool for the respondents. 101 nationals from different African countries who reside in Ghana were sampled to participate in the study. The study found strong negative security perception, low level of knowledge regarding cyber awareness and a lax attitude in cyber hygiene practices to ensure personal safety when online. Impact of culture on online security perception was not identified, and also respondents were not collectivist in their cultural orientation, a marked shift from long held opinion of strong collectivism in Africa. Implications are also discussed.
Multi-Route Plan for Reliable Services in Fog-Based Healthcare Monitoring Systems
Authors: Zeghib Nour El Imane , Alwan Ali A. , Abualkishik Abedallah Zaid , Gulzar Yonis
Published: July 2022

The main concern of fog computing is reducing data transmission on the cloud. Moreover, due to the short distance between end-user and fog nodes, fog computing considered more reliable to handle time-sensitive situations like the critical data provided by the Internet of Things (IoT). This may include sensory healthcare data which needs rapid processing to make decisions. However, in healthcare monitoring systems it is necessary to ensure the services’ availability when fog node failure occurred. The issue of monitoring service interruption during fog node failure has not received much attention. This paper proposes a multi-route plan that aims to identify an alternative route to ensure the availability of time-critical medical services. Various scenarios have been designed to evaluate the performance of the proposed strategy. The experimental results illustrate the superiority of our approach in terms of latency, energy consumption, and network usage in comparison with most recent related work.
Digital Disruption in the Accounting Profession
Authors: Mandilas Athanasios A. , Kourtidis Dimitrios , Petasakis Ioannis E. , Valsamidis Stavros Ioannis
Published: July 2022

The purpose of this study is to analyze the results of the impact of digitalization to Greek accountants. How technology has greatly improved the work of the accountant since technology nowadays is evolving rapidly in relation to the past. Finally, it highlights disruption to traditional accounting practice and research. In order to ascertain the views of professional accountants on the impact of digitalization, a research conducted in October and November 2019, in the areas of Alexandroupolis, Drama, Kavala, Komotini and Xanthi. A 40-item self-administrative questionnaire was chosen to collect the data for the research. One hundred accountants of the aforementioned areas replied to the questionnaire. The findings present their current technology infrastructure and their use of digital services. Finally, it draws useful insights regarding the effect of digital disruption on the profession of accountant.
Multi-Level Testing Approach for Multi-Agent Systems
Authors: Kissoum Yacine , Redjimi Mohammed
Published: July 2022

The software development cycles need product testing. There is a crucial lack in testing phases of multi-agent systems. To this end, a call for an investigation of appropriate testing techniques is necessary to provide adequate software development processes and supporting tools. Among all existing solutions of the test, the model-based testing technique –MBT) has gained attention with the popularization of models both in software design and development. This technique uses a so-called abstract test model to generate abstract test cases. After their concretization, concrete test cases are submitted to the system under test. The systems outputs are finally compared to the abstract test model expected results. In this context, a model-based testing approach for multi-agent systems based on the Reference net paradigm is proposed in this paper. A running example supported by a multi-agent testing prototype, which aims at simplifying and providing a uniform and automated way for multi-agent systems testing is presented and discussed.
A CNN Model for Early Leukemia Diagnosis
Authors: Imane Kadi , Abbas Messaoud , Miloudi Amara , Meftah Mohammed Charaf Eddine
Published: July 2022

Blood cancer (leukemia) is one of the most serious diseases that affect blood-forming tissues. It usually involves white blood cells. The early detection of this severe disease helps doctors to provide efficient treatment. However, the discovery of this sickness at its first stages is often not easy due to similar morphological characteristics of malignant and healthy blood cells. Flow cytometry was the only used technique for early detection of leukemia, but it is very expensive and usually unavailable in hospitals. Deep learning is a machine learning technique that teaches computers to do what comes naturally to humans learn by examples. In the last few years, deep learning has achieved great successes to solve concrete problems. In particular, it has proven successful in medical imaging classification. In this work, we propose a Convolutional Neural Network (CNN) experiment for the classification of malignant white blood cells from normal ones using a dataset of microscopic images. The proposed approach leads to a balanced model that reaches a high level accuracy.
Meaning Negotiation Based on Merged Individual Context Ontology and Part of Semantic Web Ontology
Authors: Graba Dalila Djoher , Keskes Nabil , Bensaber Djamel Amar
Published: July 2022

The meaning negotiation process has become a confusing term in the pragmatic web. It does not depend only on convenience to agree, but requires an excellent choice of terms used in the negotiated domain. The presented paper proposes a meaning negotiation model using ontologies merging into several domains and contextual situations. The idea is to design meaning negotiation scenarios using ontologies merging extended into several domains. The results obtained show the impact of merging in meaning negotiation on the multi-agent systems. The influence of merging is interpreted by the dependence between two variables: the meaning negotiation step numbers and the merging ontologies. The authors observe the difference between meaning negotiation step numbers with and without merging. They conclude that merging ontologies has a positive influence on meaning negotiation in different contextual situations of scenarios. To demonstrate the influence, an observable analytical study proof under statistical control is applied.
Multi-Biometric Iris Recognition System Using Consensus Between Convolutional Neural Network Architectures
Authors: Hammou Djalal Rafik , Mahmoudi Sidi Ahmed , Adjoudj Reda
Published: July 2022

The field of biometrics represents an important domain and is currently undergoing extensive research to improve data security. Among the most used biometric modalities, we find the iris which, is specific and adequate. It is unique for each human being. Iris identification is used at international airports, sea, and land borders. In this article, we propose to use convolutional neural networks (CNN) with a consensus between the architectures (VGG, DenseNet, Resnet, Inception, MobileNet, and Xception). The goal is to classify and combine CNN architectures with the Softmax classifier focusing on consensus orientation using a voting system (Hard voting). In addition, the use of optimization techniques such as Transfer learning, Batch-normalization, Dropout, Data augmentation, Global average pooling, and Cross-validation will accelerate the learning process and avoid overfitting. Using the GPU with its parallelization will significantly speed up the processing of our program. The experiments of our approach were carried out on the MMU1 iris database with an accuracy reaching 100%.
An Empirical Investigation on Vulnerability for Software Companies
Authors: Peng Jianping , Zhang Guoying , Chiu Chun-Hung
Published: July 2022

This research analyzes software vulnerability information from the perspective of software companies. A total of 13019 vulnerabilities from 136 software companies were collected from a public vulnerability database. A latent class model classifies the companies into three classes based on vulnerability information during a five-year period, and then three class-specific models pinpoint the most significant key features of vulnerabilities for each class. A class I company can reduce vulnerability level if it puts focus on "boundary condition errors," "input validation errors," and "exception handling errors." A class II company needs to emphasize "access validation errors" and "race condition errors." Interestingly, a class III company needs to avoid any potential "origin validation errors," "boundary condition errors," "design errors," and "access validation errors." With these significant key features information, software companies can effectively reduce vulnerability by managing related errors throughout the development and testing process.
Effect of active airway warming with a heated-humidified breathing circuit on core body temperature in patients under general anesthesia: a systematic review and meta-analysis with trial sequential analysis
Authors: Lee Je Jin , Choi Geun Joo , Lee Won Jun , Choi Sang Bong , Kang Hyun
Published: July 2022

Background: The application of a heated-humidified breathing circuit (HHBC) may reduce respiratory heat loss during mechanical ventilation, but its effect in preventing intraoperative hypothermia is controversial. This study aimed to investigate the effectiveness of HHBC in maintaining the core temperature of patients receiving mechanical ventilation under general anesthesia.Methods: We searched MEDLINE, Embase, Cochrane library (CENTRAL), and Google Scholar to identify all randomized controlled trials (RCTs) up to February 2022 that compared the intraoperative core temperature in patients with heated humidifier (HH) and other circuit devices. The primary outcome was the intraoperative core temperature at the end of surgery. The weighted mean differences (WMDs) between the groups and their 95% CIs were calculated for each outcome. We performed a trial sequential analysis of the primary outcomes to assess whether our results were conclusive.Results: Eighteen RCTs with 993 patients were included in the analysis. A significantly higher core temperature was observed at the end of surgery in patients with HH than those with no device (WMD = 0.734, 95% CI [0.443, 1.025]) or heat and moisture exchanger (WMD = 0.368, 95% CI [0.118, 0.618]), but with substantial heterogeneity.Conclusions: Although HHBC did not absolutely prevent hypothermia, this meta-analysis suggests that it can be used as an effective supplemental device to maintain the intraoperative core temperature under general anesthesia. However, considering the substantial heterogeneity and limitations of this study, further well-designed studies are needed to clarify the effectiveness of HHBC.
Evaluation of Anti-Inflammatory and Antipyretic Activities of The Aqueous Stem Bark Extract of Lophira Lanceolata Van Tiegh. Ex Keay
Authors: Muhammad A.A. , Lawal A.A.
Published: July 2022

The bark of Lophira lanceolata (Ochnaceae) has been used traditionally for the treatment of many disease conditions such as dysentery, headaches, diarrhoea, cough, abdominal pains, fungal infections, nociception and cardiovascular diseases. However, no specific work on its anti-inflammatory or antipyretic effect has been reported which forms the basis of this study. This study evaluates the in-vivo anti-inflammatory and antipyretic activities of the aqueous extract of the stem bark of Lophira lanceolata using laboratory animal model. The methods adopted for this study were formalin induced inflammation and yeast induced hyperpyrexia in rats. All the results were expressed as mean ± S.E. The data were statistically analysed by one way analysis of variance (ANOVA) followed by Dunnett's multiple comparison and p-values 0.05 were considered as significant. The result of this study showed a significant anti-inflammatory effect different from the control (distilled water) at p 0.05 characterized by oedema formation, change in temperature, redness, and itching in the paw of the rats which is comparable with the standard indomethacin. The inhibition of oedema was statistically dose dependent as the group 4 rats which received 400 mg/kg body weight demonstrated more effect than the group 1 rats which received 100 mg/kg body weight of the aqueous extract of the stem bark of Lophira lanceolata. The aqueous at the dose of 400 mg/kg body weight showed the highest antipyretic effect. Hence the antipyretic activity was also dose- dependent. The study demonstrated that the aqueous Lophira lanceolata stem bark extract possesses anti-inflammatory and antipyretic activities.
Talinum trangulare (Waterleaf) Stem Extract Has Reno-Hepato Protective Potentials than Ameliorative Effects on Acetaminophen Toxicity in Sprague-Dawley Rats
Authors: Erameh Theophilus Ogie , Moses-Otutu Ifueko Mercy , Nwaobi Anthony Chukwuemeka , Odigie Efosa Bolaji , Akpeji Blessing Eshovo , Yahaya Ramatu
Published: July 2022

Acetaminophen intoxication is not uncommon globally while herbs are increasingly utilized to counter many synthetic adverse drug reactions over time. It is against this concept that we investigated renal and hepatic protective/ameliorative potentials of Taliumtrangulare stem extract on acetaminophen toxicity in rats. In-bred Sprague-Dawley rats of both gender, 12-15 weeks old and weighed 188-202g were grouped (A to F, n=4) in a sanitized facility, wire-gauzed, and bedded with wood-dust. They adapted to facility temperature (25 ± 5ºC), humidity (45± 5%) and photoperiods (12:12hr day/night) for 14 days. Pelletized feeds® and water were provided while animal weights were measured before and after treatment. Control (group A) was untreated; group B administered 500 mg/kg b.w. T. trangulare L. extract while, Group C received 500 mg/kg b.w. acetaminophen. Group D treated with 500 mg/kg b.w. extract and 500 mg/kg b.w. acetaminophen. Group E administered 500 mg/kg b.w. acetaminophen and 500 mg/kg b.w. extract. Group F administered mixture of 500 mg/kg b.w. and 500 mg/kg b.w. acetaminophen. All rats were treated by oral intubation for 40 days at two days interval and sacrificed by cervical dislocation. Blood sample was collected through cardiac puncture to determine kidney and liver functions while related organs were protective potentials against acetaminophen intoxication in renal and hepatic cells than reversal effects.
Pelagic and demersal fish diversity of the Saya de Malha and Nazareth Banks, Mascarene Plateau
Authors: Caussy Luvna , Melanie Rodney , Souffre Andrew , Hollanda Stephanie , Olsen Magne , Gendron Gilberte , Ramah Sundy
Published: July 2022

The Saya de Malha (SMB) and Nazareth Banks (NB) are the main offshore locations where fishing activities are carried out by the Republic of Mauritius, targeting mainly shallow water Lethrinids, deep-water snappers and groupers. A multi-disciplinary survey was carried out on the two banks in May 2018 on-board the R/V Dr. Fridtjof Nansen with the objective of studying the diversity of fish on both banks using pelagic trawls, bottom trawls, basket traps and video using a Remotely Operated Vehicle (ROV). Analysis of data showed that the main fish family recorded in the pelagic waters of SMB, using pelagic trawl, was Myctophidae while the bottom trawls on NB showed the presence of fishes from the families Gobiidae, Triglidae and Synodontidae, mainly at depths between 200 and 300 m. The ROV video analysis highlighted principally the presence of demersal fishes of the family Lethrinidae and other reef-associated and commercial families recorded between 20 and 50 m. The main catch from the basket traps set at the SMB was Lethrinus mahsena, caught at a depth of 21 m. While previous studies focussed mainly on commercial fishes, this study brings forth new information on other fish families, contributing to the knowledge of the fish community that exists at these two banks.
First in-situ observation of the endemic giant clam Tridacna rosewateri from the Nazareth Bank, Mascarene Plateau
Authors: Ramah Sundy , Kaullysing Deepeeka , Bhagooli Ranjeet
Published: July 2022

Field note - N/A
Chronic inflammatory demyelinating polyneuropathy in children: modern criteria for establishing diagnosis and pathogenetic treatment
Authors: Kurenkov Alexey L. , Bursagova Bella I. , Podkletnova Tatyana V. , Abdullaeva Luiza M.
Published: July 2022

Chronic inflammatory demyelinating polyneuropathy (CIDP) in children is a rare disease, the genesis of which is autoimmune disorders. In CIDP, autoimmune inflammatory processes are mediated by disorders of both the cellular and humoral links of the immune system. Manifestations of demyelination can be observed on any segment of the peripheral nerve from the spinal roots to its distal parts. Currently, there are typical CIDP and CIDP variants. The diagnosis of CIDP is based on the results of the analysis of the patient’s anamnesis, neurological examination and electromyography (EMG) data, which indicate typical signs of demyelinating peripheral nerve damage. Recognition of the clinical phenotype of CIDP variants is crucial, since the diagnostic process and differential diagnosis may differ when compared to typical CIDP. In accordance with the recommendations of the European Academy of Neurology and Peripheral Nerve Society in 2021, fulfillment or incomplete fulfillment with diagnostic clinical and EMG criteria allows making the diagnosis in two categories - “CIDP” and “possible CIDP”. Supportive criteria are used to verify the diagnosis of CIDP only in patients with a “possible” diagnosis. If two supportive criteria are met, then the diagnosis is changed, for example, to “Typical CIDP” or one of the CIDP variants. In pediatric practice, of the supportive criteria, an objective response to treatment with immunomodulatory agents with an objective assessment of clinical improvement and cerebrospinal fluid analysis to detect protein-cell dissociation are most often used. As an induction of pathogenetic treatment of the first line in CIDP children, it is preferable to use 10% intravenous immunoglobulins (IVIg) with an IgG content of more than 95%. The earliest possible use of first-line pathogenetic treatment makes it possible to achieve remission and stop the progression of the disease. The use of adequate supportive treatment using IVIg or subcutaneous immunoglobulins help to stabilize the child’s condition and prevent the formation of neurological deficits.
A clinical case of successful management of a patient with Duchenne muscular dystrophy caused by a nonsense mutation in the DMD gene
Authors: Podkletnova Tatyana V. , Kuzenkova Lyudmila M. , Kurenkov Alexey L. , Uvakina Evgeniya V. , Popovich Sofya G. , Lyalina Anastasiya A.
Published: July 2022

Duchenne muscular dystrophy (DMD) is a hereditary progressive muscular dystrophy with an X-linked recessive type of inheritance, mainly manifested in boys, characterized by an onset at an early age, rapidly progressive atrophy of the striated muscles of the limbs, trunk, and damage of cardiac muscle. This process leads to a gradual loss of motor skills, cardiovascular and respiratory complications, deterioration of the musculoskeletal system, which, ultimately, significantly worsens the patient’s quality of life and reduces its duration. Currently, there are new drugs for the pathogenetic therapy of DMD. Their effectiveness is maximum with early initiation of therapy in the outpatient stage of the disease. Therefore, the age of diagnosis and the ability to suspect pathology in its early stages has become especially relevant in recent years. One of the new treatments for DMD is ataluren therapy. This therapy refers to pathogenetic and similar affects a number of patients with a nonsense mutation in the DMD gene. The combination of ataluren and glucocorticosteroids can increase the duration of the outpatient period and stabilize the state of respiratory and cardiac functions. The article presents a clinical example of a three-year follow-up of a patient suffering from DMD due to a nonsense mutation in the DMD gene, receiving combination therapy with glucocorticosteroids and ataluren.
Masa đačke torbe učenika mlađeg školskog uzrasta
Authors:   Institute for the Improvement of Education Belgrade, Marković Miroslav P. , Marković Živorad M. ,   University of Kragujevac, Faculty of Education in Jagodina, Milošević Živan N.
Published: July 2022

Considering the findings of previous research studies which had shown that excessive mass of the school bag can cause various deformities of the locomotor system in students, the aim of this paper was to investigate whether the percentage of students’ body weight and the weight of their school bags meet the prescribed standards, as well as to investigate the attitude of lower elementary school students towards the heavy school bag. The obtained results indicate that the mass of the school bag increases with children’s age and grade. Moreover, the vast majority of children carry a school bag which mass exceeds 10% of their body mass. The results of the survey showed that 68.6% of children go to and come back from school on foot, crossing a distance up to one kilometer (71.3%), carrying a bag on their own (81.9%). Finally, 65.2% of the surveyed children carried an ergonomic bag with reinforcements.
Magnet-škole i različiti aspekti njihovog delovanja
Authors:   University of Novi Sad, Faculty of Philosophy, Bosanac Maja M. , Milutinović Jovana J.
Published: July 2022

Starting from the position that innovations in education are becoming an imperative of educational systems, this paper deals with magnet schools that, although repre- senting the American model of public, government schools, attract the attention of researchers and educators outside the American continent. The aim of this paper is to analyze the basic characteristics of magnet schools in the context of global trends and modern educational poli- cies. This goal is conceptualized within three tasks: (1) investigating global trends in education with special emphasis on the question of school choice, (2) presenting the emergence of magnet schools and analyzing their basic characteristics, (3) examining the effects of magnet schools. Based on theoretical analysis, it is concluded that magnet schools, as schools of choice that attract students and parents interested in certain contents or approaches to education, have the potential to act towards equal opportunities for quality education, by introducing innovations in educational practice, they strive to simultaneously promote the quality of education, equality and social justice.
Pengaruh Gaya Kepemimpinan Dan Kompetensi Terhadap Kinerja Pegawai Kelurahan Perwira Kecamatan Bekasi Utara
Authors: Herlinawati Herlinawati , Fauzan Fadlan Ahmad
Published: July 2022

Penelitian ini dilakukan bertujuan untuk mengetahui pengaruh gaya kepemimpinan dan kompetensi terhadap kinerja pegawai Kelurahan Perwira Kecamatan Bekasi Utara. Penelitian ini menggunakan pendekatan kuantitatif dan menggunakan data primer melalui penyebaran kuesioner kepada 34 responden pegawai Kelurahan Perwira Kecamatan Bekasi Utara. Teknik pengambilan sampel menggunakan sampel jenuh. Data diproses melalui program SPSS versi 25.0 dengan teknis analisis regresi linear berganda. Dari hasil uji t membuktikan bahwa secara parsial gaya kepemimpinan tidak berpengaruh secara signifikan terhadap kinerja pegawai dengan nilai signifikansi sebesar 0.846 > 0.05, sedangkan kompetensi berpengaruh secara signifikan terhadap kinerja pegawai yang ditunjukkan dari perolehan nilai signifikan 0.001 < 0.05. Kemudian dari hasil uji F membuktikan bahwa gaya kepemimpinan dan kompetensi secara simultan berpengaruh secara signifikan terhadap kinerja pegawai Kelurahan Perwira Kecamatan Bekasi Utara dengan nilai signifikansi 0,000 < 0.05. Adapun besar kontribusi pengaruh gaya kepemimpinan (X1) dan kompetensi (X2) terhadap kinerja pegawai (Y) sebesar 40% sedangkan sisanya 60% terdapat faktor-faktor lain yang tidak diteliti dalam penelitian ini seperti disiplin kerja, mutasi kerja, etos kerja, dll
Should firms leverage Social Media usage to enhance Supply Chain Efficiency? A Post Covid-19 Empirical Investigation
Authors: Abbasi Muhammad Nauman , Hassan Nadir Munir , Abbas Javaria , Liaqat Tahreem
Published: July 2022

With the unavoidable spread of post-covid-19 digitization across the globe, firms have started opting for social media usage to meet the emerging competitive business landscape. Accordingly, this paper intends to investigate the impact of social media usage on supply chain efficiency. Furthermore, it also aims to observe the mediating role of both quality and intensity of knowledge sharing between social media usage and supply chain efficiency. Structured, survey questionnaires along with a convenience sampling technique were used to collect data from 312 active social media users. Appropriate supply chain representatives which majorly includes manufacturers, retailers, and consumers were taken from the Fashion Industry of Pakistan. The overall result depicts that social media usage across the supply chain is significantly related to supply chain efficiency. Results also validate the mediating role of intensity and quality of knowledge sharing, for enhancing overall supply chain efficiency through social media usage. The findings assist supply chain channel members across industries of Pakistan in general, and the fashion retail industry in particular. The study clearly, propagates the integrated and multi-layered social media usage across supply chains, for anticipated SC efficiency and related performance outcomes.
Anti-BP180 NC16A IgG Titres as an Indicator of Disease Activity and Outcome in Asian Patients with Bullous Pemphigoid
Authors: Cai Sophie CS , Lim Yen Loo , Li Wenyun , Allen John Carson , Chua Sze Hon , Tan Suat Hoon , Tang Mark BY
Published: July 2022

Introduction: Anti-BP180 IgG titres were observed to parallel disease activity in case series of bullous pemphigoid (BP). This study aimed to examine whether anti-BP180 titres are an indicator of disease severity, clinical course and outcome in Asian patients with BP. Materials and Methods: This was a prospective observational study conducted between March 2005 and March 2008 in the Immunodermatology Clinic at the National Skin Centre, Singapore. Disease activity and anti-BP180 IgG titres were measured 4-weekly for 12 weeks and during disease fl ares and clinical remission. Associations between anti-BP180 titres and disease activity, disease fl are, clinical remission and cumulative prednisolone dose were examined. Results: Thirty-four patients with newly diagnosed BP were recruited. Median follow-up duration was 3 years. Notable correlations between disease activity and anti-BP180 titres were at baseline (r = 0.51, P = 0.002), and disease fl are (r = 0.85, P <0.001). Lower titres at Week 12 were associated with greater likelihood of clinical remission (P = 0.036). Post hoc, patients with anti-BP180 titres above 87.5 U/mL at time of diagnosis who reached remission within 2 years of diagnosis received signifi cantly higher cumulative doses (mg/kg) of prednisolone (median, 72.8; range, 56.5 to 127.1) than those with titres <87.5 U/mL (median, 44.6; range, 32.5 to 80.8); P = 0.025). Conclusion: Anti-BP180 titres may be a useful indicator of disease activity at time of diagnosis and at disease fl are. Lower titres at Week 12 may predict greater likelihood of clinical remission. Titres above 87.5 U/mL at time of diagnosis may suggest the need for higher cumulative doses of prednisolone to achieve remission within 2 years. Key words: Immunobullous disease, Subepidermal skin blistering, Tense skin blisters
Metropol Kentte Prekarya Olgusunun Göçmen Karşıtlığına Etkisi: Fatih İlçesi Örneği/The Effect of Precariat Phenomenon on the Anti-Immigration Attitudes in Metropolitan City: The Example of Fatih District
Authors: KOÇAK Tuğba
Published: July 2022

2011 yılında Suriye’de başlayan iç savaş ile başlayan göç dalgasının 11.yılında Türkiye’de yaşayan Suriyeli sığınmacı sayısı 4 milyona yaklaşmıştır. Emek piyasasına kayıtdışı dahil olmaları sebebiyle “ucuz işgücü” konumunda olan Suriyeliler işverenler için bir tercih sebebi olmaktadır. Esnek istihdamın yaygınlaşması, metropol kentlerde rekabetin artması ve yaşam şartlarının zorlaşması, güvencesiz istihdam edilen bireyleri toplumda ikincil konumda olan göçmenleri suçlamaya itmektedir. Suriyeliler hem güvencesiz ve kötü şartlarda çalışarak prekarya olgusunun bir parçası olurken hem de iş piyasasında tercih edilmeleri nedeniyle yerliler tarafından suçlanmakta ve tehdit olarak gösterilmektedir. Bu araştırma prekaryal çalışma biçiminin içinde yer alan bireylerin, Suriyelilere yönelik tutumunu incelemek ve prekaryal emeğin göçmen karşıtlığında ne derece etkili olduğunu tespit etmeyi amaçlamaktadır. Araştırma nicel ve nitel yöntem birlikte kullanılarak yürütülmüştür. Araştırmanın nicel boyutunda Fatih ilçesinde geçici, güvencesiz ve güvenceli çalışan 154 bireye anket uygulanmış olup, araştırmanın nitel boyutunda yarı yapılandırılmış soru formu kullanılarak 9 işçi ve 4 işveren ile derinlemesine mülakat gerçekleştirilmiştir. Elde edilen nicel veriler SPSS programıyla analiz edilmiş olup betimsel ve regresyon analizlerine yer verilmiştir. Nitel veriler içerik analizi yöntemiyle, elde edilen temalar kapsamında karşılaştırmalı olarak analiz edilmiştir. Araştırma sonucunda prekaryal çalışma biçiminin göçmen karşıtlığı üzerinde anlamlı bir etkiye sahip olduğu tespit edilmiştir. Ancak Fatih ilçesindeki yaşanan olumsuz değişim ve kayıtdışı çalışmanın engellenmesine yönelik güvenli ve güvencesiz istihdam edilen bireylerin benzer tutumlara sahip olduğu tespit edilmiştir.
Effectiveness of Distribution Zakat Infaq Sedekah Funds To Improve Mustahik Education Stages Through Achieving Orphans Scholarship Program At Yatim Mandiri Jombang
Authors: Fitriyah Lailatul Fitriyah , Supriyadi Ahmad
Published: July 2022

This research is a field research that uses a descriptive qualitative approach, which in this study describes the effectiveness of the distribution of zakat infaq and alms funds to increase the level of mustahik educators through the achievement orphan scholarship program at the Mandiri Jombang orphanage. Data obtained by researchers through direct interview observations from informants and documentation. for the data that has been collected then analyzed through 3 stages, namely data redaction, data exposure and drawing conclusions.

The distribution of alms infaq funds at the Mandiri orphanage in Jombang Regency in the achievement orphan scholarship program is fairly good because this institution has used the zakat infaq alms funds properly. Namely, by distributing zakat infaq alms funds on the basis of the educational welfare of poor orphans and their distribution has been achieved on the target of distributing zakat infaq and alms funds, it is quite effective in improving the welfare of mustahik through the orphan scholarship program, the achievements of the Independent Orphan Institute, Jombang Regency, which can be seen from the satisfaction parents who feel that their economy has been helped by the help of this program. the second is the number of orphans who have completed their education. The third is that many of them are helped by the additional learning system that is carried out in each of the closest studios, so that orphans and needy people feel helped if there are difficulties regarding learning at school. Lessons in the studio are held four times a week.