bluuebunny/crossref_metadata_2025 huggingface dataset:
Stress echocardiography in the diagnosis of cardiac dysfunction in the early post-infarction period
Authors:   Ulyanovsk State University, VOROBEV A. M. , RUZOV V. I. ,   Ulyanovsk State University, MELNIKOVA M. A. ,   Central City Clinical Hospital, KADEBINA V. A. ,   Central City Clinical Hospital
Published: September 2023

The purpose — to assess the importance of stress echocardiography in identifying the nature and severity of cardiac dysfunction in patients with myocardial infarction. Material and methods.86 patients were examined at the outpatient stage of rehabilitation 6 weeks after myocardial infarction with primary coronary angioplasty with stenting. Results.Echocardiography revealed left ventricular hypertrophy (LVH) in 34 patients with myocardial infarction with concomitant arterial hypertension. Patients with LVH are characterized by more pronounced structural and functional LV remodeling, which is expressed in a lower LVEF and increased LVEDD, LVESVand LVEDV(p<0.05). There were no differences in stroke volume between patients with and without LVH. The performed diastolic stress test in patients with LVH is characterized by significantly lower average early diastolic mitral annular velocity e` (7.6 vs. 9.3 cm/s, p<0.01) without differences in the peak early transmitral Doppler flow velocity E (69.8 vs 78.0, p>0.05) compared with patients without LVH. The revealed differences between patients with and without LVH are due to a higher post-exercise velocity e` in patients with normal LV geometry and a decrease in eccentric LVH subgroup. Conclusions.1) Patients with LVH in the early postinfarction period (6 weeks) have more pronounced LV systolic dysfunction, expressed in a decrease in LVEF and an increase in LVEDD, LVESV, LVEDV compared to patients without LVH.2) Left ventricular hypertrophy, in conditions of myocardial infarction, is associated with latent diastolic dysfunction, which is manifested by a lower average early diastolic mitral annular velocity e` after the stress-test.
Neurotoxic complications of chemotherapy in children with acute lymphoblastic leukemia
Authors:   Ural State Medical University, KORYAKINA O. V. , CHEREPANOVA D. S. ,   Ural State Medical University
Published: September 2023

Modern therapy of acute lymphoblastic leukemia in children shows high efficiency. However, the outcome of the disease is often determined by the toxicity of chemotherapy drugs. In particular, neurotoxicity, which is characteristic of most anticancer drugs, can lead to severe neurological disorders, which significantly aggravates the course of the underlying disease and determines the formation of disability. The article presents two clinical cases that demonstrate severe chemoinduced neurological disorders in children. In the first case, damage to the central nervous system due to intraventricular administration of methotrexate is described. The second case demonstrates a severe degree of chemoinduced polyneuropathy with vincristine. Both children received the status of a patient in need of palliative care because of the complications received. The presence of such cases in practice dictates the need to develop new diagnostic methods aimed at early detection of neurotoxic complications, as well as to identify groups with high risk of the formation of chemoinduced neurological disorders.
The rs5219 polymorphism of KCNJ11 gene in predicting the risk of type 2 diabetes mellitus
Authors:   Kazan State Medical University, KHASANOVA K. B. , VALEEVA F. V. ,   Kazan State Medical University, YILMAZ T. S. ,   Kazan State Medical University, VALEEVA E. V. ,   Kazan State Medical University, BIKANOVA A. A. ,   Kazan State Medical University, BAREEVA L. T. ,   Republic Clinical Hospital of the Ministry of Health of the Republic of Tatarstan
Published: September 2023

The purpose — to study the possibility of using rs9939609 T/A polymorphisms of the FTO gene, rs5219 C/T of the KCNJ11 gene, rs1801282 C/G of the PPARG gene, rs8192678 G/A of the PPARGC1A gene, rs12255372 G/T and rs7903146 C/T of the TCF7L2 gene as markers for predicting the risk of developing type 2 diabetes mellitus in patients with T2DM risk factors. Material and methods. 112 overweight/obese patients from the Republic of Tatarstan (79% women and 21% men) aged 22 to 79 years participated in a single–center observational cohort 3-year prospective study. All patients were clinically examined, glucose tolerance test was performed, the level of glycated hemoglobin was determined, and polymorphisms rs9939609 T/A of the FTO gene, rs5219 C/T of the KCNJ11 gene, rs1801282 C/G of the PPARG gene, rs8192678 G/A of the PPARGC1A gene, rs12255372 G/T and rs7903146 C/T of the TCF7L2 gene were studied using PCR in real-time mode. Statistical analysis was performed with R 4.1.0 software. Univariable and multivariable logistic regression modeling were performed to evaluate association between outcomes and possible predictors. Area under the ROC-curve and Nagelkerke pseudo R-squared was used to compare prognostic performance of predictors. Results. According to the result of logistic regression (p=0.003), the carrier of the T allele KCNJ11 rs5219 is an independent risk factor for T2DM regardless of gender, age, waist circumference (WC), waist–hip ratio (WHR) and waist-to-height ratio (WHtR) and can be attributed as a marker of increased risk of T2DM. The inclusion of this polymorphism into T2DM clinical risk models, taking into account gender, age, maternal obesity, WHR and WHtR indices showed an increase of AUC from 0.74 to 0.78 (p=0.012) and from 0.73 to 0.79 (p=0.0056), respectively. Conclusion. The rs5219 polymorphism of the KCNJ11 gene can be used as an independent marker for predicting the risk of developing type 2 diabetes mellitus. The inclusion of this polymorphism in the risk model, which takes into account, in addition to the maternal obesity, the indices of WHtR or WHR, improves its predictive ability.
Outcome of 49 Iraqi adult patients with Chronic Lymphocytic Leukemia treated with oral alkylating agent:
Authors: Naji Alaadin S.
Published: September 2023

Background: Chronic lymphocytic leukemia (CLL) is a heterogeneous disease with an extremely variable course. Survival after diagnosis can range from months to decades and wide variability exists in the rate of disease progression and the incidence of disease-related complications among patients with CLL. Staging helps to define prognosis and to decide when to initiate therapy.Objective: To asses response to oral alkylating therapy and to evaluate the adverse events that can complicate the disease itself or the treatment, including infections, autoimmune and other complications. The survival events are also been assessed.Patients and methods: Forty nine Iraqi CLL patients, their age ranged between 40-90 years were followed with median duration of 28 months. During the follow up period of these patients, the events that complicated the disease or therapy were recorded. The primary endpoints were response rates, quality of response, Secondary endpoints of the study were overall survival , progression-free survival and event free survival. Response rates were calculated for 40 patients who were treated for at least 6 months. All patients were treated with intermittent pulse therapy of oral single alkylating agent.Results: The majority of patients recruited either had intermediate or advanced stage disease in 45(91%) patients .Autoimmune phenomena, were documented in 5(10.2%)patients. There was increased incidence of infections with either viral or bacterial pathogen, complicating the course of disease in 20 (40.8%). Remission state was mainly with partial response in 26/40(65%).In12(24.4%) patients the disease progressed and death occurred in 6(12.2% ) patients ,4(8.1% )of them were CLL(related) and 2(4.08%)of them unrelated(stroke, ischemic heart disease) to CLL with median progression free survival(PFS)and overall survival(OS) for these patients were not reached, with 2 years PFS and OS were70%.Conclusion: Although CLL is an indolent disease still the course is complicated by many events like autoimmune problem and infections whether related to CLL or to treatments. Alkylating agent were effective therapy in the treatment of CLL and the majority of patients in this study partially responded
Postanowienie o ogłoszeniu upadłości jako akt kreujący funkcję sędziego-komisarza
Authors: Wysmulska Monika
Published: September 2023

Wyznaczenie sędziego-komisarza jest przypisane kognicji sądu upadłościowego rozpoznającego wniosek o ogłoszenie upadłości w wypadku, gdy wniosek taki zostanie pozytywnie zweryfikowany tzn. gdy zostanie ogłoszona upadłość dłużnika. Emanacją tego obowiązku jest dyspozycja art. 51 prawa upadłościowego i naprawczego, w której ustawodawca wymienił elementy każdego postanowienia o ogłoszeniu upadłości wskazując w pkt 6, iż jednym z tych elementów jest wyznaczenie obok syndyka, nadzorcy sądowego lub zarządcy, sędziego-komisarza.
Long noncoding RNA LINC00885 upregulates NCK1 to promote cell viability and migration of triple-negative breast cancer cells through sponging miR-654-3p
Authors: He Peina , Liu Zhi , Qi Jinxu , Shan Junrao , Sheng Jianyun
Published: September 2023

BACKGROUND:

LINC00885 is a novel oncogenic long noncoding RNA (LncRNA) which is upregulated in various types of cancer, but its function in triple-negative breast cancer (TNBC) remains unknown.

OBJECTIVE:

This study aimed to determine the role of LINC00885 on TNBC development.

METHODS:

Clinical interrelation and survival analysis were determined using online database. The CCK-8 and Transwell assays were used to detect the proliferation and migration behaviors in TNBC cell lines. The interaction among genes was detected by RNA pull down assay.

RESULTS:

LncRNA LINC00885 was highly expressed in TNBC compared to normal breast like. Low levels of LINC00885 was related to good prognosis in TNBC patients compared to TNBC patients with high LINC00885. LINC00885-downregulation inhibited, whereas LINC00885-overexpression promoted the proliferation and migration capability of TNBC cell lines. In TNBC cell lines, noncatalytic region of tyrosine kinase 1 (NCK1) expression was positively associated with LINC00885 expression, and shRNA-mediated the depletion of NCK1 significantly abolished LINC00885 upregulation-mediated pro-tumor effects. Combined with online databases, miR-654-3p was screened as the direct target gene of LINC00885, which could directly bind to 3’-untranslated regions (3‘-UTR) of NCK1, resulting in the decreased expression of NCK1 in TNBC cell lines. LINC00885 overexpression-mediated the upregulation of NCK1 was abrogated by miR-654-3p mimics. MiR-654-3p mimics significantly rescued the tumor promotive role caused by LINC00885-overexpression. However, exogenous NCK1 notably eliminated the anti-tumor effects caused by miR-654-3p mimics in LINC00885-overexpressed cells.

CONCLUSIONS:

LINC00885 is expressed at a high level in TNBC. LINC00885 promoted proliferation and migration by regulating the miR-654-3p/NCK1 axis in TNBC cell lines. Possibly, LINC00885 can be served as a potential therapeutic target for TNBC.
Lagrange-enhanced GRA method for probabilistic simplified neutrosophic MADM: Yaozhou porcelain decoration design quality evaluation
Authors: Liu Qian
Published: September 2023

Yaozhou ware is located in Huangbao Town, Tongchuan City. It began in the Song Dynasty and flourished in the Tang Dynasty. Its warm and jade like glaze color, exquisite decorative techniques, and rich and varied utensil shapes all give it a very important position in history. The traditional Yaozhou porcelain contains the ancient people’s concept of creation and their attitude towards humans and nature. Each artifact of Yaozhou porcelain contains the designer’s understanding and emotions about the world, establishing a dialogue between people and objects to form a desired lifestyle. The production method of Yaozhou porcelain that has been preserved for thousands of years shares many similarities with modern design ideas. The quality evaluation of Yaozhou porcelain decoration design is viewed as multiple-attribute decision-making (MADM). The grey relational analysis (GRA) is a useful tool to cope with the MADM issue. The probabilistic simplified Neutrosophic set (PSNSs) is easy to characterize uncertain information during the quality evaluation of Yaozhou porcelain decoration design. In this paper, in order to obtain the weight information, an optimization model is constructed to obtain a simple and exact formula which can be employed to derive the attribute weights values based on the Lagrange function and the probabilistic simplified neutrosophic (PSN) grey relational analysis (PSN-GRA) method is originated for MADM to rank the decision alternatives. Finally, a numerical example for quality evaluation of Yaozhou porcelain decoration design is used to verify the practicability of the PSN-GRA method and compares it with other methods.
Exploring T-spherical fuzzy sets for enhanced evaluation of vocal music classroom teaching
Authors: Lu Yani
Published: September 2023

Vocal music is a relatively complex skill and skill course, which not only plays an important role in music education in universities, but also cultivates students’ musical level and artistic cultivation. In the process of teaching vocal music in universities, how to improve the quality of teaching has become an important task and goal for teachers. The vocal music classroom teaching quality evaluation is a classical multiple-attribute group decision-making (MAGDM) problem. In this paper, some novel Dice similarity measures (DSM) and some generalized Dice similarity measures (GDSM) are proposed under T-spherical fuzzy sets (T-SFSs). Then, the weighted generalized Dice similarity measures (WGDSM) is used to solve the MAGDM with T-SFSs. Finally, an illustrative example for vocal music classroom teaching quality evaluation is given to demonstrate the efficiency of the GDSMs.
Fuzzy generator and fuzzy cogenerator
Authors: Rath Abhishek Kumar , Ranadive A.S. , Pamucar Dragan
Published: September 2023

In this article, we introduce the fuzzy generator and fuzzy cogenerator and investigate some of their properties. Necessary and sufficient conditions for a fuzzy module to become a fuzzy generator and sufficient conditions for a fuzzy module to become a fuzzy cogenerator have also been established. We also discuss the behavior of fuzzy modules of finitely generated modules. Further, we introduce fuzzy trace and fuzzy reject and establish some specific results. Finally, we define a faithful fuzzy module and weave this notion with the concepts of fuzzy generator and fuzzy cogenerator.
L. vannamei shells reduces atherogenic index of plasma: A preclinical study in diabetic rats
Authors: Ayuningtyas Rr. Annisa , Djamiatun Kis , Agustini Tri Winarni , Dewi Luthfia
Published: September 2023

BACKGROUND:

Cardiovascular disease (CVD) appears to be the fundamental cause of morbidity and mortality in type 2 diabetes mellitus (T2DM). Improving the level of lipoprotein ratios using natural ingredients was widely used.

OBJECTIVE:

This study aimed to examine antioxidant source-Litopenaeus vannamei shell powder (LVSP) to rebalance the lipoprotein ratios in diabetic rats.

METHODS:

A-14 days prior to streptozotocin (STZ) injection, male Wistar rats ( n = 30) were evenly grouped into non-intervention (C–), pre-intervention high-fat diet ( C+), pre-intervention high-fat diet with LVSP dose 0.89 g/body weight (BW), pre-intervention high-fat diet with LVSP dose 1.77 g/BW (T2), and pre-intervention high-fat diet with astaxanthin 0.09 mg/BW (T3).

RESULTS:

A reduction of LDL, total cholesterol (TC), and TC/HDL, LDL/HDL, and LDL/TC ratio was observed ( p < 0.001). A negative, strong correlation was found between the change of adiponectin to the change of TC ( r=–0.94), LDL ( r=–0.92), TC/HDL ( r=–0.94), LDL/HDL ( r=–0.91), and LDL/TC ( r=–0.82). The magnitude of improvement showed a dose-dependent manner, and the high dose delineated a comparable effect to astaxanthin.

CONCLUSION:

The present study brought a profound finding on the potential of LV to reduce cardiovascular index in T2DM rats.
Application of remote electrocardiogram monitoring systems in chest pain centers for patients with high-risk chest pain
Authors: Wei Wei , Lu Lin-Xiang , Hao Ying , Kang Sheng , Liu Yonghua , Yu Jing , Chen Wenli , Fan Cheng-Hui
Published: September 2023

BACKGROUND: Chinese chest pain centers (CPCs) have been expanding and maturing for the past decade, but patient wait times for pre-hospital care remain long. OBJECTIVE: To demonstrate that the remote electrocardiogram (ECG) monitoring system can ensure more efficient treatment for patients with ST-elevation myocardial infarction (STEMI) in CPCs, we compared patients with high-risk chest pain who used remote ECG monitoring systems to those who used conventional ECGs in retrospective cohort study. METHODS: Based on the inclusion and exclusion criteria, 290 patients who visited our CPC between June 2019 and March 2022 with acute chest pain and a diagnosis of STEMI as well as patients who had undergone an emergency primary percutaneous coronary intervention were selected. Among them, 73 patients with STEMI had employed remote real-time dynamic 12-lead ECG monitoring devices, while 217 patients with STEMI (i.e., the controls) had used conventional ECG monitoring. The effectiveness of treatment procedures for the two groups was investigated. As statistical measures, the symptom onset-to-wire times, first medical contact (FMC)-to-wire times, door-to-wire times, major adverse cardiac events in hospital, and the troponin T levels were analyzed. RESULTS: Compared with the control group, the patients with remote real-time dynamic 12-lead ECG monitoring devices showed shorter times for both symptom onset-to-wire (234.8 ± 95.8 min vs. 317.6 ± 129.6 min, P= 0.0321) and from symptom onset-to-FMC (170.5 ± 86.3 min vs. 245.3 ± 115.6 min, P= 0.0287); this group also had a lower 30-day mortality rate (2.73% vs. 4.14%, P= 0.003). The differences between the two groups were statistically significant (P< 0.05). CONCLUSION: With remote real-time dynamic 12-lead ECG monitoring equipment, myocardial ischemia can be treated more quickly, leading to fewer possible cardiac events and a better prognosis.
Effect of smokeless tobacco on color stability and surface roughness of CAD/CAM milled, 3D printed, and conventional provisional crown and fixed dental prosthesis materials: An in vitro study
Authors: Sayed Mohammed E. , Jain Saurabh , Jokhadar Hossam F. , Alshahrani Ahid Amer , AlResayes Saad Saleh , Alqahtani Saeed M. , Alqarni Hatem , Anab Najwa Ali , Alsubeaie Nouf H. , Alsubaie Shaa H. , Khalid Asaad , Franco Rocco , Minervini Giuseppe
Published: September 2023

BACKGROUND: Provisional fixed dental prosthesis (FDP) plays an important role during fixed prosthodontic therapy till the definitive. Discoloration of materials used for provisional FDPs can cause patient dissatisfaction and may create doubt about the color stability of the definitive FDP. Surface roughness is the other major property to be taken into consideration for provisional FDP materials. Smokeless tobacco is reported to affect the color stability and surface roughness of different prosthetic materials. OBJECTIVE: The aim of the current study was to evaluate the effect of two types of smokeless tobacco (black and white) on color stability and surface roughness of 3D printed, CAD/CAM milled, and conventional provisional FDP resin materials. METHODS: A total of 144 disc-shaped specimens were fabricated using four techniques CAD/CAM subtractive technique (milling), CAD/CAM additive technique (3D Printing), and conventional technique using autopolymerized PMMA, and autopolymerized Bis-acrylic resins. Each group was subdivided into three subgroups of twelve specimens each, and were submerged into three solutions (artificial salivary substitute, black smokeless tobacco, white smokeless tobacco). The change in color and surface roughness was evaluated and the data collected were statistically analyzed. RESULTS: It was observed that black smokeless tobacco caused the maximum color change and the effect was highest in autopolymerized PMMA resin specimens (ΔE = 9.343 ± 0.489), followed by 3D printed (ΔE = 7.187 ± 0.391), autopolymerized Bis-acryl (ΔE = 6.464 ± 0.453) and milled (ΔE = 4.978 ± 0.227). White smokeless tobacco was found to cause a maximum change in surface roughness and the effect was highest in autopolymerized Bis-acryl specimens (ΔRa = 0.321 ± 0.015 μm), followed by autopolymerized PMMA (ΔRa = 0.297± 0.015 μm), 3D printed (ΔRa = 0.191 ± 0.019 μm), and milled (ΔRa = 0.168 ± 0.014 μm). Statistically significant (p-value < 0.05) differences were observed among all techniques and solutions. CONCLUSIONS: The change in color and surface roughness were maximum in the case of FDPs prepared using autopolymerizing resins, followed by 3D printed, and CAD/CAM milled reins.
The Systematic Review of Shariah Governance in Islamic Banking System: A Meta-Synthesis Approach
Authors: Abdullah Mahmoud , Said Muhammad , Mufraini Arief
Published: September 2023

The purpose of this systematic review is to analyze and discuss Shariah Governance in the Islamic banking system from multiple integrative studies. The following study as a meta-synthesis approach employs the ENTREQ technique based on the inductive reasoning approach synthesized selected studies for the issue of Shariah Governance in the form of secondary data. A qualitative analysis research method is used to discuss the given issue systematically. This study employs a meta-synthesis approach of 40 research papers with 4 themes - Shariah audit, Shariah risk, Shariah supervisory, and Shariah Board which are the functions of Shariah Governance. The systematic review of synthesizing finds that Shariah Governance in Islamic banking has its strengths and weaknesses in improving the stability and performance of the Islamic Banking system based on the Shariah compliance requirements. In addition, the result and discussion of the present systematic review have two sections: synthesis finding and synthesis evaluation.
Faktor Pendukung Perkembangan Usaha Konveksi
Authors: Rahayu Siti Nurpuji , Sainul Sainul , Nuriasari Selvia , Suci Okta Adioni Tinokae Rahma
Published: September 2023

The clothing industry is very promising and the conditions for profit are in line with the rise of clothing trends or fashions in society. Departing from this, today there are small and medium businesses that produce clothes (convection) causing a great deal of market competition. This has resulted in many convection businesses not being able to develop or even experiencing setbacks. But behind the high market competition, there are still many convection businesses that are still able to maintain their existence or even develop, one of which is the Abu Bakar Convection business. Departing from this, the purpose of conducting this research is to find out the factors that influence the development of the Abu Bakar Convection business. According to Hendro, there are 8 factors that can affect business development, namely opportunity factors, human resources, finance and administration, organization, planning, business management, marketing and sales, and government assistance.This study uses a qualitative descriptive analysis method with data collection techniques through interviews and documentation. Based on the research results, there are 6 factors that influence the development of the Abu Bakar Convection business, namely opportunity factors, human resources, organization, planning, business management, and marketing and sales.The results of this study can be used as a basis for making policies for business owners of Abu Bakar Convection to improve their business development and can also be used as learning for prospective entrepreneurs, especially in the convection sector.
Improving English Vocabulary Mastery by Using the Alphabet Game for Class VIII at Junior High School Metro TMI RQ Metro
Authors: Pauliana Riska , Suhono Suhono , Pratiwi Wiwied , Sari Yeasy Agustina
Published: September 2023

The students was the lack of enthusiasm for English learning. Students sometimes get bored in learning process. The purpose of this research was to improve how to get well students at SMP TMI RQ Metro in acquire English vocabulary material for class VIII A. The researchers used classroom action research, either in Cycle I and Cycle II. Data was collected through observation, interviews, tests and documentation. The result showed that 9 out of 20 students passed with a percentage of 45% in the observation cycle I. 11 students with a completeness level of 55% were students who did not complete. with an average value of 70.75. Hence, the classical completeness of the first cycle is 45%. It was observed that 80% of 20 students, 16 of which completed it during the second cycle. Four students with a 20% completion rate did not complete the course. with an average of 80 points. As a result, a typical cycle II is 80% complete. In other words, the results of the second cycle of observations succeeded in obtaining the KKM score that had been determined by the school and the completeness of the learning objectives for students.Keywords: Student Learning Outcomes, Vocabulary Material, Alphabet Games
Nilai-Nilai Kebangsaan pada Organisasi Ikatan Pelajar Muhammadiyah dan Ikatan Pelajar Nahdlatul Ulama Provinsi Lampung
Authors: Nurkholis Nurkholis , Syahid Akhmad
Published: September 2023

Nahdlatul Ulama and Muhammadiyah are organizations that have a large number of members, so an appropriate formula is needed to unify perceptions of how the nation and state live, and how efforts are made to fortify its members from the influence of the swift currents of globalization, including their students. Based on this, the authors are interested in conducting research to find out about the implementation of national values ​​in NU and Muhammadiyah students in Lampung Province.

This study uses a type of qualitative research, and uses two data sources, namely primary data and secondary data. Primary data were obtained directly from education managers within NU and Muhammadiyah, NU and Muhammadiyah administrators and students. Secondary data is obtained from documents in the form of books, brochures, reports and so on. After the data is collected, the data is analyzed using qualitative data analysis techniques with inductive thinking methods and descriptive analysis.

The national values ​​of NU and Muhammadiyah students look quite good and can influence the mindset of students, including by increasing a high sense of nationalism and always maintaining unity and oneness. This implementation can be seen in the existence of material on understanding national values, which is always carried out either directly or indirectly in every activity. The national values ​​given include religion, kinship, mutual cooperation, tolerance between religious communities and fellow religious people and always maintaining the unity and integrity of the nation.
Pengembangan Bahan Ajar Sejarah Kebudayaan Islam berbasis Higher Order Thinking Skill di MTS Diniyyah Pasia
Authors: Melvarisa Ranti , Junaidi Junaidi , Ariza Hidra
Published: September 2023

Learning material of Islamic Cultural History (SKI) in class VII MTs Diniyyah Pasia only came from books which were not relevant to students' needs. Therefore, the development of valid, effective and practical SKI based on Higher Order Thinking Skill (HOTS) teaching materials is absolutely necessary. This study aims to develop SKI teaching materials based on higher order thinking skills.

The methodology used in this research is research and development. The development technique uses a case based reasoning system. The series of learning activities use a scientific approach that is integrated with the 2013 curriculum. The learning models used are problem-based learning, contextual-based learning, and comprehensive concept understanding.

The teaching materials that have been developed have met the validity test requirements with a test score of 96% based on expert/lecturer assessments. This teaching materials module has a practicality test score of 91.4% and is declared very practical. This teaching material module is also declared effective with a correlation value of 0.78 and has an influence of 78% on improving student learning outcomes.
Approaches to evaluating the efficiency of CRM systems
Authors: Oksamytna Liubov , Praha Roman
Published: September 2023

In today's world, CRM systems are an integral part of business. They have gained great popularity in recent years. The relevance of the application and evaluation of the effectiveness of CRM systems is considered, which is entirely determined by the modern needs of the company's business management based on such systems. It was determined that the evaluation of the effectiveness of CRM systems helps to evaluate the effectiveness of the use of the system and to make the necessary adjustments. The analysis of literary sources from the research of many scientists on the problems of evaluating the effectiveness of CRM systems was carried out. The feasibility of evaluating the effectiveness of CRM systems for the company is caused by the need for a comprehensive evaluation of the system's effectiveness from the point of view of its ability to improve customer service; increase customer loyalty; generate more sales; return on investment. The purpose of this work is to review the existing approaches to assessing the effectiveness of CRM systems. The need to apply the basic approaches to evaluate the effectiveness of CRM systems, which are studied in the work, is determined by the introduction of processes of automation, marketing, work with clients and data analysis. Each of them is used depending on the specific business needs of the company, its goals and has advantages and disadvantages. The authors present the features of methods for evaluating the effectiveness of CRM systems. It was determined that the analysis of indicators of client activity is one of the most powerful marketing tools for evaluating the effectiveness of CRM systems. It allows companies to adapt their products and services to the specific needs of customers and increase sales efficiency. Equally important and one of the most common approaches is the analysis of marketing effectiveness. It is useful for determining the effectiveness of marketing strategies and advertising companies used in the CRM system. The evaluation of the effectiveness of the CRM system using the analysis of the level of customer satisfaction is described in detail. It is determined that the marketing research of consumer satisfaction for the company is based on several main performance indicators: CSAT, NPS, CES. Performance analysis is presented, which allows you to evaluate the effectiveness of the CRM system by comparing the performance of personnel before and after using the system. The analysis of technical support and resources is considered - relevant and necessary for any company that works with technology. It is useful for determining the effectiveness of the use of technical support and resources needed to work with the CRM system.
Modeling of thermo-elastic properties of composite material in stability problems of multilayered shells
Authors: Krivenko Olga P. , Lizunov Petro , Vorona Yurii , Kalashnikov Oleksandr
Published: September 2023

Thin-walled structures, the elements of which are plates and shells made of composite materials, are increasingly used in various industries. The growing needs of practice and the introduction of new composite materials require further improvement of the calculation methods of shell structures of inhomogeneous structure. Therefore, the problem of developing an adequate method of analyzing the behavior of shells made of composite materials with a multilayer structure is relevant. The work is devoted to the application of the developed method of finite elements for the analysis of geometrically nonlinear deformation and stability of elastic shells to the problem of the study of shells, the layer materials of which are composites of a fibrous structure. The method of structuring materials through the shell thickness and plan by using a universal 3D finite element is applied to model the thermoelastic properties of a ingomogeneous material. Determination of the effective characteristics of the composite material is realized by the structural micromechanical parameters of its components based on known methods of predicting elastic constants for this model of the composite material. The multilayer finite element, created within the framework of the developed approach, can be exploited to the problems of calculating thin elastic shells from both traditional and composite materials. The results of investigation of a multilayer composite panel using various micromechanical techniques are presented. The results of the study of a multilayer composite panel obtained by various micromechanical methods are given. These results are consistent with those obtained using the NASTRAN software. The new modification of the developed finite element makes it possible to analyze the stress-strain state and stability of multi-layer shells made of fibrous composite materials reliably, with accuracy acceptable for engineering calculations.
Possible connections between relativity theory and a version of quantum theory based upon theoretical variables
Authors: Helland Inge Svein
Published: September 2023

An alternative approach towards quantum theory is described, and tentative attempts to connect his approach to special and general relativity are discussed. Important concepts are gauge groups and information/entropy connected to some physical systems. Some recent results on information in connection to black holes are touched upon, and it is indicated how expected information can be argued to be conserved. This argument only depends on what happens outside the black hole. Everything connected to the interior of the black hole is inaccessible.
Correlated noise enhances coherence and fidelity in coupled qubits
Authors: Bittner Eric , Li Hao , Shah S. A. , Silva Carlos , Piryatinski Andrei
Published: September 2023

It is generally assumed that environmental noise arising from thermal fluctuations is detrimental to preserving coherence and entanglement in a quantum system. In the simplest sense, dephasing and decoherence are tied to energy fluctuations driven by coupling between the system and the normal modes of the bath. Here, we explore the role of noise correlation in an open-loop model quantum communication system whereby the "sender" and the "receiver" are subject to local environments with various degrees of correlation or anticorrelation. We introduce correlation within the spectral density by solving multidimensional stochastic differential equations and introduce these into the Redfield equations of motion for the system density matrix. We find that correlation can enhance both the fidelity and purity of a maximally entangled (Bell) state. Moreover, we show that, by comparing the evolution of different initial Bell states, one can effectively probe the correlation between two local environments. These observations may be useful in the design of high-fidelity quantum gates and communication protocols.
Why a uniformly accelerated classical charge must radiate
Authors: Onoochin Vladimir
Published: September 2023

It is generally accepted that all quantities of electromagnetic origin are either relativistic scalars or components of relativistic four-vectors and tensors. This opinion is based on the Lorentz invariance of the Maxwell equations and this opinion is so commonly established that no one tries to verify this symmetry of electromagnetic fields. The idea that any EM field is covariant and, therefore, its components are changed in accordance with the Lorentz transformations in a new inertial reference frame, is used in studying some electrodynamical systems. One such application of this concept is to apply the Lorentz transformation of the EM field created by a uniformly accelerated charge to show that this charge does not radiate.

However, am analysis of the EM fields created by this charge and calculated in two inertial frames shows that the required Lorentz covariance of these fields is absent.

The explanation of violation of such a Lorentz covariance is given in this work.
Influence of Allergy, Asthma Treatment(AT) and Eviction Diet(ED) on Sleep-Disordered Breathing(SDB) in Pediatric Asthma Associated With Osa, Increased Respiratory Effort(RE) During Sleep and Overweight/Obesity: a Study in 78 Children
Authors: Kefala Kalomoira , Guerin Philippe
Published: September 2023

Pathophysiological mechanisms and allergies in Obstructive Sleep Apnoea-asthma associated are unclear. Apnoea hypopnea Index alone does not seem sufficient to correctly guide for adequate treatment without identification of the specific profile of each patient. Obstructive Sleep Apnoea correlates to obesity; however, links between obesity, allergy, and Obstructive Sleep Apnoea remain unexplored. Obese allergic children with Obstructive Sleep Apnoea increase their Body Mass Index despite adequate weight interventions.

We aimed to study the Respiratory Polygraphy/Polysomnography profile of children suffering Obstructive Sleep Apnoea-asthma associated and the influence of allergies and Asthma Treatment/Eviction Diet upon Apnoea Hypopnea Index/Respiratory Effort/Body Mass Index to diagnose, treat and prevent pediatric Obstructive Sleep Apnoea-asthma associated and related obesity early and accurately.

We effectuated a cross-sectional/case controls diagnostic cohort. We used Receiver Operating Characteristic curves, General Linear Models, regression, and path analysis to evaluate the effect of treatments and allergies on Apnoea Hypopnea Index, Respiratory Effort, Body Mass Index and Polygraphy/Polysomnography parameters such as Respiratory Distress Index, Sleep Fragmentation, Sleep Fragmentation Ventilatory Origin, Oxygen Desaturation Index.

We identified that asthma treatment and specific allergen eviction, along with the co-existence of non-IgE-mediated and respiratory allergies, influence the Apnoea Hypopnea Index, Respiratory Effort during sleep and the Body Mass Index.

Allergies, asthma treatment and allergen eviction are implicated in the pathophysiological mechanisms of Obstructive Sleep Apnoea and obesity. Consideration of asthma treatment, allergies, and allergen eviction upon interpretation of polygraphy/polysomnography parameters could ameliorate the diagnosis and treatment of Obstructive Sleep Apnoea-asthma associated and possibly avoid, upon their origin, asthma, and obesity.
Sentiment Analysis of Opinions about Online Education in the Kurdistan Region of Iraq during COVID-19
Authors: Sami Maryam , Hassani Hossein
Published: September 2023

Sentiment analysis is widely used in various areas and has versatile applications. For example, it is used in market research, customer retention strategies, and product analysis, to name a few. Although some previous work on the topic exists for the Kurdish language, similar to other fields in Kurdish processing, it is not well-studied, and particularly it suffers from data inadequacy. In this paper, we present an overview of the research we conducted to analyze the sentiments of learners/educators toward online education during COVID-19 in the Kurdistan Region of Iraq. We collected the data from Tweets tweeted up to March 2022. After preprocessing, 511 items remained. The dataset is publicly available for non-commercial use under CC0 1.0 Universal license at https://github.com/KurdishBLARK/SentimentAnalysis/tree/main/OnlineEducation-during-COVID-19
Cultural Phenomenon of Mass Event
Authors: Zasyadvovk Olga
Published: September 2023

The purpose of the article is to research urban mass events as a specific form of public communication, its institutional and communicative characteristics, and the peculiarities of its current state. Research methodology. The method of analysis is applied to investigate scientific theories on the key concepts of the study; the method of analogy is used to examine factual materials on the cultural phenomenon of the mass event; the method of comparison contributed to the establishment of common and distinctive advantages in modern mass events. The cultural approach has become the key to the theoretical justification of the phenomenology of modern events as phenomena of cultural and practical activity. The scientific novelty of the work is an attempt to theoretically conceptualise the phenomenon of mass events from the standpoint of the cultural approach as phenomena that are an important factor in the formation of socio-cultural aspects of social development, and its value self-determination. Conclusions. Mass festivals and spectacles exist in every society as an indispensable institution, a social and cultural phenomenon that unites different segments of the population, forming a peculiar form of regulation of human activity. It is a dynamic structure, the development of which is carried out in the general field of the historical and cultural environment, which determines the nature and content. Mass festivals and spectacles as the most important component of the history and modernity of culture are an integral element of the socio-cultural system, and with a reasonable approach to this phenomenon, could serve as a guarantee of social harmony and integration.
Key words: Ukrainian national holidays, modern events, mass events, cultural phenomenon.
Frame Design in Visual Culture of Contemporary Filmmaking.
Authors: Pogrebnіak Galyna
Published: September 2023

The purpose of the article is to define the artistic and aesthetic toolkit of frame design in the visual culture of auteur film directing. Research methodology. In developing the topic, an integrated approach was applied, in particular, the methods of systematisation, comparison, verification, comparative and textual analysis were used. The analytical method and the method of figurative and stylistic analysis in their unity were aimed to consider the art historical aspect of the problem. The scientific novelty of the research is that the director's creativity is studied in the context of the visual culture of frame design and for the first time became the subject of a special study. The appropriateness of using the systematic method in studying the features of the author's plastic film language has been proven. A comprehensive analysis has been conducted and the features of frame design in the author's film work have been revealed. Conclusions. The materials presented in the study expand the arsenal of knowledge about the specifics of the visual culture of the author's film language in various worldview models and enable their application in educational courses, the creation of educational and methodological literature on the theory and history of cinema and television, directing.
Key words: visual culture, author's cinematography, director, frame, design, screen art, composition, colour.
Futuristic Design of Transforming Furniture in the First Half of the Twentieth Century: Concepts and Perspectives
Authors: Bosyi Ivan , Bryzhachenko Natalia
Published: September 2023

The purpose of the article is to identify the main concepts of creating futuristic transforming furniture of the first half of the 20th century and to determine their influence on contemporary design practice. The research methodology is based on a historical and comparative analysis of the design of futuristic transformer projects of the first half of the 20th century and their comparison with modern design solutions. This allowed the authors to identify the influence of new ideas on the further development of furniture design and outline the features of forming a small-sized residential object-spatial environment. The study also used such theoretical methods of cognition as analysis, comparison, abstraction, and generalisation. The methods of analysis and comparison of the features of structural elements and characteristic features of the formation of futuristic transformer objects of the specified historical period allowed identifying the leading concepts of their creation. The methods of abstraction and generalisation were used to summarise the results of the work. The scientific novelty of the work lies in identifying the prerequisites for the emergence of multifunctional transforming furniture in European countries in the first half of the 20th century, highlighting the concepts of creating transforming objects and outlining the impact of these predictive developments on modern furniture design. Conclusions. The study has revealed that the leading concepts of creating futuristic-transforming furniture in the first half of the 20th century are: 1) rationality of design; 2) multifunctionality; 3) laconism of forms; 4) introduction of innovative technologies and use of modern materials; 5) interactivity.
Key words: transforming furniture, historical furniture prototypes, transformation systems, conceptual design.
WWII in Work of Front-Line Artists through the Prism of Military Events of the Present
Authors: Nedoshovenko Tamara
Published: September 2023

The purpose of the study is to supplement the understanding of the works of Kyiv front-line artists of WWII against the background of the events of the war launched by Russia against Ukraine in 2014 and the full-scale invasion of 2022; to show the formation of the worldview of the artist-soldier, whose life truth of war was transformed into the artistic truth of the created images. The attention is selectively focused on artists whose works became iconic in the Ukrainian fine arts of the second half of the 20th century. The research methodology is based on the application of such scientific methods as historical, similarities, observation, comparison, as well as the method of artistic cognition of reality. The scientific novelty of the work lies in the systematisation and generalisation of the topic of the WWII from the perspective of the current Russian-Ukrainian war and the reflection of military events by artists who participated in WWII. The self-sacrifice and heroism of the individual became the basis for the disclosure of their chosen theme by means of artistic expression and can be seen as a projection for the future disclosure of the war theme in a new generation of artists, our contemporaries. Conclusions. During WWII, Ukrainian artists fought and worked between battles on the frontlines and in army units. Their memories, mostly written on the basis of diaries, reflected the personal experience of each author. Memoirs, short-term sketches testify to the impressions, experiences, thoughts, and aspirations of young artists – patriots who defended their native land with arms, but remained artists in the content of their spiritual life.
Key words: truth of life, artistic truth, war, artist, worldview, painting.