bluuebunny/crossref_metadata_2025 huggingface dataset:
Organic carbon prediction in soil cores using VNIR and MIR techniques in an alpine landscape
Authors: Jia Xiaolin , Chen Songchao , Yang Yuanyuan , Zhou Lianqing , Yu Wu , Shi Zhou
Published: May 2017

Diffuse reflectance spectroscopy (DRS), including visible and near-infrared (VNIR) and mid-infrared (MIR) radiation, is a rapid, accurate and cost-effective technique for estimating soil organic carbon (SOC). We examined 24 soil cores (0–100 cm) from the Sygera Mountains on the Qinghai–Tibet Plateau, considering field-moist intact VNIR, air-dried ground VNIR and air-dried ground MIR spectra at 5-cm intervals. Preprocessed spectra were used to predict the SOC in the soil cores using partial least squares regression (PLSR) and a support vector machine (SVM). The SVM models performed better with three predictors, with the ratio of performance to inter-quartile distance (RPIQ) and R2 values typically exceeding 1.74 and 0.73, respectively. The SVM using the DRS technique indicated accurate predictive results of SOC in each core. The RPIQ values of the shrub meadow, forest and total dataset prediction using air-dried ground VNIR were 1.97, 2.68 and 1.99, respectively; the values using field-moist intact VNIR were 1.95, 2.07 and 1.76 and those using air-dried ground MIR were 1.78, 1.96 and 1.74, respectively. We conclude that the DRS technique is an efficient and rapid method for SOC prediction and has the potential for dynamic monitoring of SOC stock density on the Qinghai–Tibet Plateau.
Realization of large energy proportion in the central lobe by coherent beam combination based on conformal projection system
Authors: Zhi Dong , Zhang Zhixin , Ma Yanxing , Wang Xiaolin , Chen Zilun , Wu Wuming , Zhou Pu , Si Lei
Published: May 2017

In this paper, we experimentally validate a tiled-aperture conformal projection system with the largest array filling factor and element beam truncation factor to the best of our knowledge. The conformal projection system, which is made up of a hexagonal adaptive fiber-optics collimator (AFOC) array with the proximate ideal intensity distributions, is fabricated and the performance of output beam is tested and evaluated properly and carefully. Both of the active phase-locking control and precise tip-tilt control are implemented successfully in the CBC of the hexagonal seven-beam-array. Experimental results show a large energy proportion (47%, which increases by over 10% comparing with the previously demonstrated largest value) in the central lobe is achieved and the residual phase error is lower than λ/27. When the AFOC array performs, the precise tilt control makes the combining beams overlap well and the average normalized metric value is improved from 0.336 without control to 0.947 with both of active piston and tip-tilt phase controls while the fringe contrast increases from 19% to more than 91% correspondingly. This work presents a promising structure for the achievement of large energy proportion in the central lobe in high power fiber laser CBC systems.
Shedding of host autophagic proteins from the parasitophorous vacuolar membrane of Plasmodium berghei
Authors: Agop-Nersesian Carolina , De Niz Mariana , Niklaus Livia , Prado Monica , Eickel Nina , Heussler Volker T.
Published: May 2017

The hepatic stage of the malaria parasite Plasmodium is accompanied by an autophagy-mediated host response directly targeting the parasitophorous vacuolar membrane (PVM) harbouring the parasite. Removal of the PVM-associated autophagic proteins such as ubiquitin, p62, and LC3 correlates with parasite survival. Yet, it is unclear how Plasmodium avoids the deleterious effects of selective autophagy. Here we show that parasites trap host autophagic factors in the tubovesicular network (TVN), an expansion of the PVM into the host cytoplasm. In proliferating parasites, PVM-associated LC3 becomes immediately redirected into the TVN, where it accumulates distally from the parasite’s replicative centre. Finally, the host factors are shed as vesicles into the host cytoplasm. This strategy may enable the parasite to balance the benefits of the enhanced host catabolic activity with the risk of being eliminated by the cell’s cytosolic immune defence.
Role of S-Palmitoylation by ZDHHC13 in Mitochondrial function and Metabolism in Liver
Authors: Shen Li-Fen , Chen Yi-Ju , Liu Kai-Ming , Haddad Amir N. Saleem , Song I-Wen , Roan Hsiao-Yuh , Chen Li-Ying , Yen Jeffrey J. Y. , Chen Yu-Ju , Wu Jer-Yuarn , Chen Yuan-Tsong
Published: May 2017

Palmitoyltransferase (PAT) catalyses protein S-palmitoylation which adds 16-carbon palmitate to specific cysteines and contributes to various biological functions. We previously reported that in mice, deficiency of Zdhhc13, a member of the PAT family, causes severe phenotypes including amyloidosis, alopecia, and osteoporosis. Here, we show that Zdhhc13 deficiency results in abnormal liver function, lipid abnormalities, and hypermetabolism. To elucidate the molecular mechanisms underlying these disease phenotypes, we applied a site-specific quantitative approach integrating an alkylating resin-assisted capture and mass spectrometry-based label-free strategy for studying the liver S-palmitoylome. We identified 2,190 S-palmitoylated peptides corresponding to 883 S-palmitoylated proteins. After normalization using the membrane proteome with TMT10-plex labelling, 400 (31%) of S-palmitoylation sites on 254 proteins were down-regulated in Zdhhc13-deficient mice, representing potential ZDHHC13 substrates. Among these, lipid metabolism and mitochondrial dysfunction proteins were overrepresented. MCAT and CTNND1 were confirmed to be specific ZDHHC13 substrates. Furthermore, we found impaired mitochondrial function in hepatocytes of Zdhhc13-deficient mice and Zdhhc13-knockdown Hep1–6 cells. These results indicate that ZDHHC13 is an important regulator of mitochondrial activity. Collectively, our study allows for a systematic view of S-palmitoylation for identification of ZDHHC13 substrates and demonstrates the role of ZDHHC13 in mitochondrial function and metabolism in liver.
High-efficiency broadband second harmonic generation in single hexagonal GaAs nanowire
Authors: Wang Jing , Yu Ying , Wei Yu-Ming , Liu Shun-Fa , Li Juntao , Zhou Zhang-Kai , Niu Zhi-Chuan , Yu Si-Yuan , Wang Xue-Hua
Published: May 2017

In this paper, we investigate second harmonic generation in a single hexagonal GaAs nanowire. An excellent frequency converter based on this nanowire excited using a femtosecond laser is demonstrated to operate over a range from 730 nm to 1960 nm, which is wider than previously reported ranges for nanowires in the literature. The converter always operates with a high conversion efficiency of ~10−5 W−1 which is ~103 times higher than that obtained from the surface of bulk GaAs. This nanoscale nolinear optical converter that simultaneously owns high efficiency and broad bandwidth may open a new way for application in imaging, bio-sensing and on-chip all-optical signal processing operations.
A heteromeric molecular complex regulates the migration of lung alveolar epithelial cells during wound healing
Authors: Ghosh Manik C. , Makena Patrudu S. , Kennedy Joseph , Teng Bin , Luellen Charlean , Sinclair Scott E. , Waters Christopher M.
Published: May 2017

Alveolar type II epithelial cells (ATII) are instrumental in early wound healing in response to lung injury, restoring epithelial integrity through spreading and migration. We previously reported in separate studies that focal adhesion kinase-1 (FAK) and the chemokine receptor CXCR4 promote epithelial repair mechanisms. However, potential interactions between these two pathways were not previously considered. In the present study, we found that wounding of rat ATII cells promoted increased association between FAK and CXCR4. In addition, protein phosphatase-5 (PP5) increased its association with this heteromeric complex, while apoptosis signal regulating kinase-1 (ASK1) dissociated from the complex. Cell migration following wounding was decreased when PP5 expression was decreased using shRNA, but migration was increased in ATII cells isolated from ASK1 knockout mice. Interactions between FAK and CXCR4 were increased upon depletion of ASK1 using shRNA in MLE-12 cells, but unaffected when PP5 was depleted. Furthermore, we found that wounded rat ATII cells exhibited decreased ASK1 phosphorylation at Serine-966, decreased serine phosphorylation of FAK, and decreased association of phosphorylated ASK1 with FAK. These changes in phosphorylation were dependent upon expression of PP5. These results demonstrate a unique molecular complex comprising CXCR4, FAK, ASK1, and PP5 in ATII cells during wound healing.
Time-course responses of circulating microRNAs to three resistance training protocols in healthy young men
Authors: Cui Shufang , Sun Biao , Yin Xin , Guo Xia , Chao Dingming , Zhang Chunni , Zhang Chen-Yu , Chen Xi , Ma Jizheng
Published: May 2017

Circulating microRNAs (c-miRNAs) in human plasma have been described as a potential marker of exercise. The present study investigated the effects of three acute resistance training (RT) protocols on the time-course changes of the c-miRNAs profiles in young males. The subjects (n = 45) were randomly divided into three groups: muscular strength endurance (SE), muscular hypertrophy (MH) and maximum strength (MS). Venous blood samples were obtained before exercise and immediately, 1 h and 24 h after each RT protocol to assess the following biological parameters: c-miRNAs, anabolic and catabolic hormones, inflammatory cytokines and muscle damage markers. The results revealed that the levels of two c-miRNAs (miR-208b and miR-532), six c-miRNAs (miR-133a, miR-133b, miR-206, miR-181a, miR-21 and miR-221) and two c-miRNAs (miR-133a and miR-133b) changed significantly in response to the SE, MH and MS protocols (p < 0.05), respectively. The nature and dynamic processes of the c-miRNAs response were likely influenced by the RT modality and intensity. Moreover, miR-532 was negatively correlated with insulin-like growth factor-1 and positively correlated with interleukin-10, whereas miR-133a was negatively correlated with cortisol and positively correlated with testosterone/cortisol. These findings suggest that these c-miRNAs may serve as markers for monitoring the RT responses.
Novel mutations and phenotypic associations identified through APC, MUTYH, NTHL1, POLD1, POLE gene analysis in Indian Familial Adenomatous Polyposis cohort
Authors: Khan Nikhat , Lipsa Anuja , Arunachal Gautham , Ramadwar Mukta , Sarin Rajiv
Published: May 2017

Colo-Rectal Cancer is a common cancer worldwide with 5–10% cases being hereditary. Familial Adenomatous Polyposis (FAP) syndrome is due to germline mutations in the APC or rarely MUTYH gene. NTHL1, POLD1, POLE have been recently reported in previously unexplained FAP cases. Unlike the Caucasian population, FAP phenotype and its genotypic associations have not been widely studied in several geoethnic groups. We report the first FAP cohort from South Asia and the only non-Caucasian cohort with comprehensive analysis of APC, MUTYH, NTHL1, POLD1, POLE genes. In this cohort of 112 individuals from 53 FAP families, we detected germline APC mutations in 60 individuals (45 families) and biallelic MUTYH mutations in 4 individuals (2 families). No NTHL1, POLD1, POLE mutations were identified. Fifteen novel APC mutations and a new Indian APC mutational hotspot at codon 935 were identified. Eight very rare FAP phenotype or phenotypes rarely associated with mutations outside specific APC regions were observed. APC genotype-phenotype association studies in different geo-ethnic groups can enrich the existing knowledge about phenotypic consequences of distinct APC mutations and guide counseling and risk management in different populations. A stepwise cost-effective mutation screening approach is proposed for genetic testing of south Asian FAP patients.
CR-39 track detector for multi-MeV ion spectroscopy
Authors: Jeong T. W. , Singh P. K. , Scullion C. , Ahmed H. , Hadjisolomou P. , Jeon C. , Yun H. , Kakolee K. F. , Borghesi M. , Ter-Avetisyan S.
Published: May 2017

We present the characteristics of track formation on the front and rear surfaces of CR-39 produced by laser-driven protons and carbon ions. A methodological approach, based on bulk etch length, is proposed to uniquely characterize the particle tracks in CR-39, enabling comparative description of the track characteristics in different experiments. The response of CR-39 to ions is studied based on the energy dependent growth rate of the track diameter to understand the intrinsic particle stopping process within the material. A large non-uniformity in the track diameter is observed for CR-39 with thickness matching with the stopping range of particles. Simulation and experimental results show the imprint of longitudinal range straggling for energetic protons. Moreover, by exploiting the energy dependence of the track diameter, the energy resolution (δE/E) of CR-39 for few MeV protons and Carbon ion is found to be about 3%.
Blocking of carnitine palmitoyl transferase 1 potently reduces stress-induced depression in rat highlighting a pivotal role of lipid metabolism
Authors: Mørkholt Anne Skøttrup , Wiborg Ove , Nieland Jette G. K. , Nielsen Søren , Nieland John Dirk
Published: May 2017

Major depressive disorder is a complex and common mental disease, for which the pathology has not been elucidated. The purpose of this study is to provide knowledge about the importance of mitochondrial dysfunction, dysregulated lipid metabolism and inflammation. Mitochondrial carnitine palmitoyl transferase 1a (CPT1a) is a key molecule involved in lipid metabolism and mutations in CPT1a causing reduced function is hypothesized to have a protective role in the development of depression. Moreover, CPT1a is found to be upregulated in suicide patients with history of depression. Therefore, we hypothesized that inhibition of CPT1a activity can be developed as an innovative treatment strategy for depression. Stress exposure combined with different pharmacological treatment regimens; Etomoxir, CPT1 blocker, and Escitalopram, a favoured antidepressant drug, was applied in state-of-the-art chronic mild stress model. Etomoxir treatment induced statistical significant reduction of anhedonic behavior compared to vehicle treatment (p < 0.0001) and reversed depression-like phenotype in 90% of the rats (p = 0.0007), whereas Escitalopram only proved 57% efficacy. Moreover, Etomoxir revealed downregulation of interferon-γ, interleukin-17α and tumor necrosis factor-α. This indicate that alteration in metabolism is pivotal in the pathogenesis of depression, since CPT1 blockage is highly efficient in treating anhedonia and inflammation, thereby opening up for a novel class of antidepressant medication.
2-Hydroxypropyl-beta-cyclodextrin (HPβCD) reduces age-related lipofuscin accumulation through a cholesterol-associated pathway
Authors: Gaspar Jason , Mathieu Jacques , Alvarez Pedro
Published: May 2017

Oxidative stress causes significant increases in both cholesterol uptake and intracellular accumulation of the aging biomarker lipofuscin. Here we show that HPβCD addition mitigates these adverse effects in human fibroblasts by significantly reducing LDLr and SREBP1 gene expression. In the absence of oxidative stress, HPβCD addition induces a paradoxical response, increasing cholesterol accumulation (but not lipofuscin) via upregulation of cholesterol biosynthesis. These two distinct, but opposite effects highlight a previously overlooked therapeutic consideration: the cholesterol content of the treated cell determines which cholesterol pathways, either beneficial or harmful, are responsive to HPβCD.
Hanbury Brown-Twiss effect without two-photon interference in photon counting regime
Authors: Bai Bin , Zhou Yu , Liu Ruifeng , Zheng Huaibin , Wang Yunlong , Li Fuli , Xu Zhuo
Published: May 2017

From quantum point of view, Hanbury Brown-Twiss effect is a result of constructive-destructive two-photon interference. There should be no Hanbury Brown-Twiss effect if there was no two-photon interference. In this paper, we observed Hanbury Brown- Twiss effect in a specially designed experiment, in which two-photon interference is impossible by keeping only one two-photon probability amplitude in the experimental scheme. However, our experimental results can still be interpreted by Glauber’s quantum optical coherence theory. The researches in our paper are helpful to understand the physics of the second-order coherence of light, especially the physics of Hanbury Brown-Twiss effect.
Electro-Tactile Stimulation Enhances Cochlear Implant Speech Recognition in Noise
Authors: Huang Juan , Sheffield Benjamin , Lin Payton , Zeng Fan-Gang
Published: May 2017

For cochlear implant users, combined electro-acoustic stimulation (EAS) significantly improves the performance. However, there are many more users who do not have any functional residual acoustic hearing at low frequencies. Because tactile sensation also operates in the same low frequencies (<500 Hz) as the acoustic hearing in EAS, we propose electro-tactile stimulation (ETS) to improve cochlear implant performance. In ten cochlear implant users, a tactile aid was applied to the index finger that converted voice fundamental frequency into tactile vibrations. Speech recognition in noise was compared for cochlear implants alone and for the bimodal ETS condition. On average, ETS improved speech reception thresholds by 2.2 dB over cochlear implants alone. Nine of the ten subjects showed a positive ETS effect ranging from 0.3 to 7.0 dB, which was similar to the amount of the previously-reported EAS benefit. The comparable results indicate similar neural mechanisms that underlie both the ETS and EAS effects. The positive results suggest that the complementary auditory and tactile modes also be used to enhance performance for normal hearing listeners and automatic speech recognition for machines.
Radiopaque Resorbable Inferior Vena Cava Filter Infused with Gold Nanoparticles
Authors: Tian Li , Lee Patrick , Singhana Burapol , Chen Aaron , Qiao Yang , Lu Linfeng , Martinez Jonathan O. , Tasciotti Ennio , Melancon Adam , Huang Steven , Eggers Mitch , Melancon Marites P.
Published: May 2017

Failure to remove a retrievable inferior vena cava (IVC) filter can cause severe complications with high treatment costs. Polydioxanone (PPDO) has been shown to be a good candidate material for resorbable IVC filters. However, PPDO is radioluscent under conventional imaging modalities. Thus, the positioning and integrity of these PPDO filters cannot be monitored by computed tomography (CT) or x-ray. Here we report the development of radiopaque PPDO IVC filters based on gold nanoparticles (AuNPs). Commercially available PPDO sutures were infused with AuNPs. Scanning electron microscopy analysis confirmed the presence of AuNP on the surface of PPDO. Micro-CT and x-ray images of the AuNP-infused PPDO sutures showed significant signal enhancement compared to untreated PPDO sutures. Elemental analysis showed that gold loading exceeded 2000 ppm. Tensile strength and in vitro cytotoxicity showed no significant difference between AuNP-infused and untreated PPDO. In a 10-week stability study, neither the gold content nor the radiopacity of the infused PPDO sutures significantly changed in the first 6 weeks. The increased attenuation of AuNP-infused PPDO sutures indicates their major advantage as a radiopaque resorbable filter material, as the radiopacity allows monitoring of the position and integrity of the filter, thereby increasing its safety and efficacy.
Highly efficient green synthesis of α-hydroxyphosphonates using a recyclable choline hydroxide catalyst
Authors: Kalla Reddi Mohan Naidu , Zhang Yu , Kim Il
Published: May 2017

Aldehydic carbonyl groups are eco-friendly and efficiently hydrophosphonylated by diethylphosphite using the basic ionic liquid, choline hydroxide.
Protein hydration in living cells probed by Fourier transform infrared (FT-IR) spectroscopic imaging
Authors: Shinzawa H. , Turner B. , Mizukado J. , Kazarian S. G.
Published: May 2017

FT-IR spectra of a HEK cell were analyzed with 2D disrelation mapping to reveal molecular states of water and protein hydration.
The influence of polydopamine coating on gold nanorods for laser desorption/ionization time-of-flight mass spectrometric analysis
Authors: Kang Kyungtae , Jang Hongje , Kim Young-Kwan
Published: May 2017

The influence of polydopamine (PD) coating on gold nanorods (GNRs) for laser desorption/ionization mass spectrometry (LDI-MS) analysis was systematically investigated to reveal its role in the LDI-MS analysis process.
Antineoplastic drugs and their analysis: a state of the art review
Authors: Guichard Nicolas , Guillarme Davy , Bonnabry Pascal , Fleury-Souverain Sandrine
Published: May 2017

We provide an overview of the analytical methods available for the quantification of antineoplastic drugs in pharmaceutical formulations, biological and environmental samples.
Determination of 11 photoinitiators and their migration into tea and milk by gas chromatography-tandem mass spectrometry (MSPD-GC-MS/MS)
Authors: Cai Huimei , Ji Shuilin , Zhang Juzhou , Shang Guangzhi , Tao Gushuai , Peng Chuanyi , Chen Guijie , Hou Ruyan , Zhang Liang , Wan Xiaochun
Published: May 2017

Based on the use of multi-walled carbon nanotubes (MWCNTs) in matrix solid-phase dispersion (MSPD) extraction, a novel, rapid and reliable method was developed for the analysis of 11 photoinitiators used in food packaging ink followed by quantitation by gas chromatography-tandem mass spectrometry.
Dielectrophoretic assembly of liquid-phase-exfoliated TiS3 nanoribbons for photodetecting applications
Authors: Frisenda R. , Giovanelli E. , Mishra P. , Gant P. , Flores E. , Sánchez C. , Ares J. R. , Perez de Lara D. , Ferrer I. J. , Pérez E. M. , Castellanos-Gomez A.
Published: May 2017

Liquid-phase exfoliation produces colloidal two-dimensional materials that can be assembled by dielectrophoresis to fabricate optoelectronic devices.
A deciduous directing group approach for the addition of aryl and vinyl nucleophiles to maleimides
Authors: Bettadapur Kiran R. , Lanke Veeranjaneyulu , Prabhu Kandikere Ramaiah
Published: May 2017

A Rh(iii)-catalyzed C–H activation followed by conjugate addition to maleimides, using carboxylic acid as a traceless/deciduous directing group, to formally furnish a Csp2–Csp3 bond is presented.
Ca-NIR: a ratiometric near-infrared calcium probe based on a dihydroxanthene-hemicyanine fluorophore
Authors: Collot Mayeul , Ponsot Flavien , Klymchenko Andrey S.
Published: May 2017

Ca-NIR is the first ratiometric fluorescent calcium probe emitting in the near infrared.
A cascade Claisen rearrangement/o-quinone methide formation/electrocyclization approach to 2H-chromenes
Authors: Song Liyan , Huang Fang , Guo Liwen , Ouyang Ming-An , Tong Rongbiao
Published: May 2017

A new approach to 8-substituted 2H-chromenes is developed, featuring a novel cascade aromatic Claisen rearrangement/o-quinone methide formation/6π-electrocyclization.
Synthesis of biotin-labelled core glycans of GPI anchors and their application in the study of GPI interaction with pore-forming bacterial toxins
Authors: Gao Jian , Zhou Zhifang , Guo Jiatong , Guo Zhongwu
Published: May 2017

A concise and convergent synthesis of biotin–GPI glycan conjugates that were utilized to explore GPI–bacterial toxin interaction.
Anisotropic thermal expansion of SnSe from first-principles calculations based on Grüneisen's theory
Authors: Liu Gang , Zhou Jian , Wang Hui
Published: May 2017

The thermal expansion of SnSe is calculated by first-principles calculations and negative thermal expansion is found along thecdirection.
Controlling the spin and valley degeneracy splitting in monolayer MnPSe3 by atom doping
Authors: Zhong Liangshuai , Chen Xiaofang , Qi Jingshan
Published: May 2017

Monolayer manganese chalcogenophosphates MnPSe3 possess a pair of non-degenerate energy valleys in the vicinities of the vertices of the hexagonal Brillouin zone, which exhibit fascinating optical valley polarization.
Tunable electronic structure and magnetic moment in C2N nanoribbons with different edge functionalization atoms
Authors: Wang Yusheng , Song Nahong , Jia Min , Yang Dapeng , Panashe Chikowore , Yang Yuye , Wang Jianjun
Published: May 2017

First principles calculations based on density functional theory were carried out to study the electronic and magnetic properties of C2N nanoribbons (C2NNRs).
BAR-based optimum adaptive sampling regime for variance minimization in alchemical transformation
Authors: Sun Zhao X. , Wang Xiao H. , Zhang John Z. H.
Published: May 2017

The efficiency of alchemical free energy simulations with a staging strategy is improved by adaptively manipulating the significance of each ensemble followed by importance sampling.
Tiny changes in local order identify the cluster formation threshold in model fluids with competing interactions
Authors: Bomont Jean-Marc , Costa Dino , Bretonnet Jean-Louis
Published: May 2017

In two-Yukawa fluids, the increment of attraction causes a tiny reversal of trend in the local density, within specific ranges of interparticle distances. This event precisely signals the onset of a clustered state.
Correction: Transformations of polyols to organic acids and hydrogen in aqueous alkaline media
Authors: van Haasterecht T. , van Deelen T. W. , Ludding C. C. I. , de Jong K. P. , Bitter J. H.
Published: May 2017

Correction for ‘Transformations of polyols to organic acids and hydrogen in aqueous alkaline media’ by T. van Haasterecht et al., Catal. Sci. Technol., 2014, 4, 2353–2366.
Synthesis of 2-substituted quinazolines by CsOH-mediated direct aerobic oxidative cyclocondensation of 2-aminoarylmethanols with nitriles in air
Authors: Yao Song , Zhou Kaijing , Wang Jiabing , Cao Hongen , Yu Lei , Wu Jianzhang , Qiu Peihong , Xu Qing
Published: May 2017

An atom-efficient synthesis of 2-substituted quinazolines is developed by a CsOH-mediated aerobic oxidative reaction of 2-aminoarylmethanols and nitriles in air.
Microwave solution route to ceramic ZnAl2O4 nanoparticles in 10 minutes: inversion and photophysical changes with thermal history
Authors: Menon Samvit G. , Choudhari Khoobaram S. , Shivashankar Srinivasrao A. , Chidangil Santhosh , Kulkarni Suresh D.
Published: May 2017

Within 10 minutes microwave synthesis using metal complexes can form crystalline ZnAl2O4 nanoparticles with significant inversion.
Correction: Studies on neptunium complexation with CMPO- and diglycolamide-functionalized ionic liquids: experimental and computational studies
Authors: Sengupta Arijit , Kumar Mohapatra Prasanta , Pathak Priyanath , Ghanty Tapan Kumar , Iqbal Mudassir , Verboom Willem
Published: May 2017

Correction for ‘Studies on neptunium complexation with CMPO- and diglycolamide-functionalized ionic liquids: experimental and computational studies’ by Arijit Sengupta et al., New J. Chem., 2017, 41, 836–844.
Bis- and mono(m-benzoic acid)-functionalized pillar[5]arenes
Authors: Wu Xin-Lang , Chen Yi , Hu Wen-Jing , Liu Yahu A. , Jia Xue-Shun , Li Jiu-Sheng , Jiang Biao , Wen Ke
Published: May 2017

Installation of m-benzoic acid functionalities on pillar[5]arene rims resulted in bis- and mono(m-benzoic acid)-functionalized pillar[5]arenes.
Structural, optical and electronic properties of a Mg incorporated GaN nanowall network
Authors: Nayak Sanjay Kumar , Gupta Mukul , Shivaprasad S. M.
Published: May 2017

In this report we study the effect of incorporation of different quantities of Mg on morphology, crystal structure and optical properties of a GaN nanowall network (NwN).
Fabrics coated with hot-iron-treated graphene oxide for a self-cleaning and mechanically robust water–oil separation material
Authors: Gong Tao , Kim Jongwoon , Woo Ju Yeon , Jang Jin-Hyeok , Lee Seung Eun , Han Chang-Soo
Published: May 2017

A simple method was reported to fabricate self-cleaning and water–oil separation fabrics sprayed with hot-iron-treated graphene oxide (GO).
Facile synthesis of Au/Al2O3nanocomposites for improving the detection sensitivity of adenosine triphosphate
Authors: Xu Li , Xu Qin , Guo Xiaoyu , Ying Ye , Wu Yiping , Wen Ying , Yang Haifeng
Published: May 2017

Alumina is widely recognized as chemically inert, and resistant to oxidation and high temperature.
Selective removal of cationic micro-pollutants using disulfide-linked network structures
Authors: Atas Mehmet Sahin , Dursun Sami , Akyildiz Hasan , Citir Murat , Yavuz Cafer T. , Yavuz Mustafa Selman
Published: May 2017

Micropollutants are found in all water sources, even after thorough treatments that include membrane filtration. We have developed swellable di-sulfide covalent organic polymers (COPs) with great affinity towards cationic textile micropollutants.
Sandwiched C@SnO2@C hollow nanostructures as an ultralong-lifespan high-rate anode material for lithium-ion and sodium-ion batteries
Authors: Qin Jian , Zhao Naiqin , Shi Chunsheng , Liu Enzuo , He Fang , Ma Liying , Li Qunying , Li Jiajun , He Chunnian
Published: May 2017

Novel interconnected sandwiched carbon-coated hollow nanostructures, i.e., carbon–shell/SnO2–nanocrystal–layer/hollow–carbon–core, were developed as SIB anode materials.
Hierarchically porous nitrogen-doped carbon nanotubes derived from core–shell ZnO@zeolitic imidazolate framework nanorods for highly efficient oxygen reduction reactions
Authors: Shi Peng-Chao , Yi Jun-Dong , Liu Tao-Tao , Li Lan , Zhang Lin-Jie , Sun Chuan-Fu , Wang Yao-Bing , Huang Yuan-Biao , Cao Rong
Published: May 2017

Porous N-doped carbon nanotubes with superior activity for ORR are fabricated by pyrolysis of core–shell ZnO@ZIF-8 nanorods.
Tailoring La1−xSrxMnO3(0.25 ≤ x ≤ 0.35) nanoparticles for self-regulating magnetic hyperthermia therapy: an in vivo study
Authors: Soleymani Meysam , Edrissi Mohammad , Alizadeh Ali Mohammad
Published: May 2017

Silica-coated La1−xSrxMnO3(0.25 ≤x≤ 0.35) nanoparticles were designed for self-regulating magnetic hyperthermia therapy. The efficacy of the prepared nanoparticles was investigated on a typical animal model of breast cancer.
Dimerization effect of fluorene-based semiconductors on conformational planarization for microcrystal lasing
Authors: Ou Chang-Jin , Zhu Can , Ding Xue-Hua , Yang Lei , Lin Jin-Yi , Xie Ling-Hai , Qian Yan , Xu Chun-Xiang , Zhao Jian-Feng , Huang Wei
Published: May 2017

Efficient ultraviolet organic microcrystal lasers were demonstrated based on bulky diarylfluorene dimers with a fully coplanar conformation.
Effects of a random copolymer's component distribution on its opto-electronic properties
Authors: Zhong Zhiming , Wang Xiaojun , Zhao Sen , Peng Feng , Wang Jian , Ying Lei , Yang Wei , Peng Junbiao , Cao Yong
Published: May 2017

The molecular weight-dependent component distribution of a random copolymer is analyzed using the binomial distribution formula.
Red-light emission and dielectric reversible duple opto-electronic switches in a hybrid multifunctional material: (2-methylimidazolium)MnCl3(H2O)
Authors: Guo Qiang , Zhang Wan-Ying , Chen Cheng , Ye Qiong , Fu Da-Wei
Published: May 2017

A new optical–electrical switching material was synthesized, and it is much superior to the predominant multifunctional devices.
Discourse Characteristics in Aphasia Beyond the Western Aphasia Battery Cutoff
Authors: Fromm Davida , Forbes Margaret , Holland Audrey , Dalton Sarah Grace , Richardson Jessica , MacWhinney Brian
Published: May 2017

Purpose

This study examined discourse characteristics of individuals with aphasia who scored at or above the 93.8 cutoff on the Aphasia Quotient subtests of the Western Aphasia Battery–Revised (WAB-R; Kertesz, 2007). They were compared with participants without aphasia and those with anomic aphasia.

Method

Participants were from the AphasiaBank database and included 28 participants who were not aphasic by WAB-R score (NABW), 92 participants with anomic aphasia, and 177 controls. Cinderella narratives were analyzed using the Computerized Language Analysis programs (MacWhinney, 2000). Outcome measures were words per minute, percent word errors, lexical diversity using the moving average type–token ratio (Covington, 2007b), main concept production, number of utterances, mean length of utterance, and proposition density.

Results

Results showed that the NABW group was significantly different from the controls on all measures except MLU and proposition density. These individuals were compared to participants without aphasia and those with anomic aphasia.

Conclusion

Individuals with aphasia who score above the WAB-R Aphasia Quotient cutoff demonstrate discourse impairments that warrant both treatment and special attention in the research literature.
Motion artefact removals for wearable ECG using stationary wavelet transform
Authors: Nagai Shuto , Anzai Daisuke , Wang Jianqing
Published: May 2017

Wearable Electrocardiogram (ECG) is attracting much attention in daily healthcare applications. From the viewpoint of long‐term use, it is desired that the electrodes are non‐contact with the human body. In this study, the authors propose an algorithm using the stationary wavelet transform (SWT) to remove motion artefact superimposed on ECG signal when using non‐contact capacitively coupling electrodes. The authors evaluate the effect on motion artefact removal of this algorithm by applying it to various ECG signals with motion artefacts superimposed. As a result, the correlation coefficients of ECG signals with respect to the clean ones have been improved from 0.71 to 0.88 on median before and after motion artefact removal, which demonstrates the validity of the proposed SWT‐based algorithm.
Performance of multicarrier cooperative communication systems over underwater acoustic channels
Authors: Al‐Dharrab Suhail , Muqaibel Ali , Uysal Murat
Published: May 2017

Multicarrier transmission in the form of orthogonal frequency division multiplexing (OFDM) is an efficient method to handle inter‐symbol interference resulting from the frequency selectivity of the underwater acoustic (UWA) channels. OFDM can be further combined with cooperative transmission to benefit from the spatial diversity advantages and improve the performance over conventional point‐to‐point UWA communication systems. In this study, the authors consider a cooperative OFDM UWA communication system and investigate the outage performance for both amplify‐and‐forward relaying and decode‐and‐forward (DF) relaying. They derive expressions for bounds on outage probability and outage capacity. Monte Carlo simulations corroborate and quantify the enhanced performance of cooperative OFDM UWA communication compared with direct transmission systems. Through numerical simulations, they investigate the impact of geometry on outage probability and signal‐to‐noise ratio requirements in cooperative OFDM UWA communication with DF relaying. Furthermore, the authors analyse the effects of relay location and carrier frequency on the outage probability for both relaying schemes.
Model predictive control of plug‐in hybrid electric vehicles for frequency regulation in a smart grid
Authors: Elsisi M. , Soliman Mahmoud , Aboelela Magdy A.S. , Mansour W.
Published: May 2017

Integration between energy storage systems and renewable energy sources (RESs) can effectively smooth natural fluctuations of the latter and ensure better frequency regulation. Optimal performance of the plug‐in hybrid electric vehicle (PEHV) battery, having longer plug‐in than driving time, makes it a good candidate for integration with RESs. Decentralised model predictive control (MPC) is proposed here for frequency regulation in a smart three‐area interconnected power system comprising PHEVs. Two MPCs in each area are considered to manipulate the input signals of the governor and PHEV in order to tolerate frequency perturbations subject to load disturbances and RES fluctuations. Setting the parameters of the six MPC controllers is carried out simultaneously based on imperialist competitive algorithm (ICA) and bat‐inspired algorithm (BIA). Time‐domain based objective function is suggested to account for system non‐linearities emanating from governor dead bands and turbine generation rate constraints. The proposed tuning procedures utilising ICA and BIA are completely accomplished off‐line. Comparative simulation results are presented to confirm the effectiveness of the proposed design.
Transmission characteristics of multi‐walled carbon nanotube‐based through‐silicon vias considering temperature effects
Authors: Su Jinrong , Chen Xinwei , Han Liping , Yang Rongcao , Zhang Wenmei
Published: May 2017

In this study, a simplified temperature‐dependent expression of electron mean free path (MFP) is proposed first. Then, the electrical model of multi‐walled carbon nanotube bundle‐based through‐silicon vias (MWCNTB‐TSVs) is established considering the temperature effects of the MFP, metal‐oxide‐semiconductor capacitance, substrate conductance and number of conducting channels of MWCNT. Based on this model, the propagation constant, forward transmission coefficient S21 and crosstalk at different temperatures are calculated. By analysing the phase constant, the zero dispersion transmission condition is obtained. According to this condition, the guidelines on how to select the substrate in different level integrations are proposed. Furthermore, a concise formula for the equivalent conductivity of MWCNTB is proposed. Moreover, the minimum diameter of MWCNTB‐TSV whose attenuation is less than that of copper‐filled TSV has been deduced.
Dual‐frequency impedance matching networks based on two‐section transmission line
Authors: Maktoomi Mohammad A. , Yadav Ajay P. , Hashmi Mohammad S. , Ghannouchi Fadhel M.
Published: May 2017

In this study, a practical and useful dual‐frequency property of two‐section transmission line (TSTL) terminated into a real impedance is reported. Moreover, to demonstrate some of its potential applications for the performance enhancement in dual‐frequency impedance transformation problems, modified L‐ and T‐type dual‐frequency matching networks are presented. Specifically, the property is used to modify the conventional L‐type matching network to improve its transformation‐ratio and frequency‐ratio performance. Furthermore, improvement in conventional dual‐frequency T‐type matching network is also demonstrated through the incorporation of the TSTL. All the results are analytical and in closed form with simple design equations. For validation, prototypes of the proposed L‐ and T‐type matching networks operating concurrently at 1 GHz/1.45 GHz and 1 GHz/2 GHz, respectively, are designed and fabricated on FR‐4 substrate. The obtained simulated and measured results clearly exhibit the usefulness of the proposed design schemes.
Intramolecular Oxidative Palladium-Catalyzed Amination Involving Double C–H Functionalization of Unactivated Olefins
Authors: Broggini Gianluigi , Borelli Tea , Giofré Sabrina , Mazza Alberto
Published: May 2017

Intramolecular palladium-catalyzed amination reactions are becoming important tools for the synthesis of various nitrogen-containing­ heterocycles. This account highlights the developments achieved in this field by domino processes in oxidative conditions using unactivated olefins, due to their advantages in terms of step economy and efficiency. These reactions involve the change of oxidation state in the palladium intermediate, requiring the presence of an oxidizing agent to regenerate the catalytic cycle. This kind of additive is essential for the success of the reaction and it can also furnish nucleophilic species that are incorporated into the final product. Reactions can occur at either the intra/intra- or intra/intermolecular level, providing valuable methodologies for the preparation of (poly)heterocyclic scaffolds. Besides, procedures based on the use of strengthened catalytic systems, more recently, disclosed intriguing conditions have enlarged the possibility to modulate the substrate reactivity. Perspectives in this field are directed to the discovery of new reaction conditions, focusing on the employment of oxidatively stable ligands useful for the asymmetric catalysis­.

1 Introduction

2 Carboamination Reactions

2.1 Pd(0)/Pd(II)

2.2 Pd(II)/Pd(IV)

3 Aminooxygenation Reactions

3.1 Pd(0)/Pd(II)

3.2 Pd(II)/Pd(IV)

4 Diamination Reactions

4.1 Pd(0)/Pd(II)

4.2 Pd(II)/Pd(IV)

5 Aminohalogenation Reactions

5.1 Pd(0)/Pd(II)

5.2 Pd(II)/Pd(IV)

6 Conclusions
Reemplazo parcial de rodilla mediante el sistema robótico NAVIO: resultados clínicos postquirúrgicos evaluados mediante Knee injury Osteoartritis Outcome Score
Authors: Vega Parra Pablo , Palacios Barajas J. , Márquez Ambrosi Raúl , Duarte Jorge
Published: May 2017

Introducción La osteoartritis de rodilla es una de las patologías musculo esqueléticas más prevalentes en el mundo, y el tratamiento quirúrgico es hasta hoy, la única terapia definitiva. El sistema NAVIO™ es uno de los dispositivos robóticos más recientemente a disposición para realizar el reemplazo parcial de rodilla. Ofrece gran precisión en el proceso de alineamiento, remodelado óseo y balance de los tejidos blandos, sin exponer al paciente a la radiación ni a los costos de la tomografía computarizada que suele realizarse con los sistemas robóticos actuales antes del procedimiento artroplástico.

Objetivo Evaluar los resultados medidos por los pacientes antes y después del procedimiento artroplástico mediante NAVIO™ y la prótesis STRIDE™.

Material y Método Aplicación del cuestionario Knee injury Osteoarthritis Outcome Score (KOOS) en el preoperatorio y a los 12 meses del procedimiento quirúrgico de los primeros 47 pacientes operados usando NAVIO™ en Cornerstone Regional Hospital, Edinburg, Texas.

Resultados Se observó una mejoría de las muestras normalizadas en todas las categorías con un p < 0.05.

Comentario Estudios recientes han sugerido que en Chile la presentación de la osteoartritis se asocia a un grado de severidad menor que en el resto de los países latinoamericanos. Lo cual torna relevante la aplicación de terapias quirúrgicas más conservadoras, que ofrezcan al paciente un alivio sintomático y le permitan reestablecerse a sus actividades cotidianas causando el mínimo impacto posible. Esas ventajas fueron observadas en los pacientes sometidos a ese procedimiento quirúrgico.

Conclusiones La artroplastia unicompartimental de rodilla mediante el sistema quirúrgico NAVIO™ y prótesis STRIDE™ demostró mejorar substancialmente la vida diaria y calidad de vida de los pacientes, disminuyendo el dolor y mejorando su función durante las actividades deportivas y recreacionales.
Vereinbarkeit von Familie und Arztberuf – eine repräsentative Umfrage in München bei Ärztinnen und Ärzten unterschiedlicher Tätigkeitsbereiche
Authors: Lauchart Meike , Ascher Philipp , Kesel Karin , Weber Sabine , Grabein Beatrice , Schneeweiss Bertram , Fischer-Truestedt Cordula , Schoenberg Michael , Rogler Gudrun , Borelli Claudia
Published: May 2017

Ziel Untersuchung der Ist-Situation der Vereinbarkeit von Familie und Arztberuf im Großraum München.

Methodik Befragung einer repräsentativen Stichprobe von 1 800 Ärztinnen und Ärzten mittels eines Fragebogens.

Ergebnisse Männer sind unzufriedener mit der Vereinbarkeit als Frauen (7% sehr zufrieden vs. 21%). Ärztinnen und Ärzte, die im Krankenhaus (KH) arbeiten sind signifikant weniger zufrieden als jene mit einem Arbeitsplatz außerhalb (p<.001, chi-Quadrat=122,75). Frauen stellen aufgrund der Kinder häufiger ihre Karriere zurück, sehen ihr berufliches Fortkommen beeinträchtigt, verzichten häufiger auf eine Niederlassung oder geben ihren Arbeitsplatz im KH auf. Die Befragten wünschen sich eine flexible Kinderbetreuung und einen Betreuungsdienst, falls die etablierte Betreuung ausfällt. Dies ist für die meisten nicht gegeben. Die Krankenhausärzte (w/m) wünschen sich planbare Arbeitszeiten, sowie Mitbestimmung bei deren Festlegung. Für den Großteil der Befragten ist dies keine Realität. 80% geben an, die Mitsprache bei der Festlegung der Arbeitszeit sei ihnen sehr wichtig, dies ist aber nur bei 17% tatsächlich gut möglich. 86% der Krankenhausärzte (w/m) ist Teilzeitarbeit wichtig, über 30% können dies an ihrem Arbeitsplatz nicht umsetzen. Bei den Niedergelassenen ist der Wunsch nach beschleunigten Verfahren durch die Kassenärztliche Vereinigung Bayern (KVB) bei der Beantragung von Vertretern am stärksten ausgeprägt. Am zweitwichtigsten ist die Möglichkeit, Notdienste abgeben zu können. Dies kann knapp ein Drittel auch realisieren. 36% der Befragten sind der Ansicht, dass die Vereinbarkeit von Familie und Arztberuf am besten außerhalb der Patientenversorgung gegeben sei, unter den Assistenzärzten in Weiterbildung (WB) sind es 42%. Nur 6% aller Befragten sehen die beste Vereinbarkeit im KH. Die Niedergelassenen halten ihre selbständige ärztliche Tätigkeit zu einem erheblichen Anteil (34%) für am besten vereinbar. Viele Fachärzte (w/m) (19%) und viele Assistenzärzte (w/m) in WB (24%) halten eine Anstellung in der Praxis für am besten geeignet. Dabei sehen Frauen häufiger als Männer (27 vs. 13,%) die Anstellung in der Praxis als beste Möglichkeit.

Schlussfolgerung In München besteht ein hoher, bislang nicht gedeckter Bedarf an flexibler Kinderbetreuung. Es besteht der Wunsch nach mehr Mitsprache bei der Gestaltung der Arbeitszeiten und der Möglichkeit, in Teilzeit zu arbeiten. Im niedergelassenen Bereich besteht der Wunsch, Vertretungsmöglichkeiten flexibler und weniger bürokratisch zu gestalten. Unter den aktuellen Bedingungen sehen sich besonders Ärztinnen am beruflichen Fortkommen gehindert. Der Arbeitsplatz Krankenhaus wird als extrem ungünstig für die Vereinbarkeit wahrgenommen. Die selbständige Tätigkeit (Praxis) wird in der Arbeitsrealität positiver bewertet als dies ihr Ruf ist.
Weaningzentrum Greifswald – Struktur und Ergebnisse bei der Entwöhnung von der Langzeitbeatmung über zehn Jahre
Authors: Müller-Heinrich A. , Warnke C. , Heine A. , Bollmann T. , Boesche M. , Schäper C. , Stubbe B. , Friesecke S. , Felix S. , Gläser S. , Obst A. , Ewert R.
Published: May 2017

Seit der Etablierung der klinischen Beatmungsmedizin gewinnt die Entwöhnung langzeitbeatmeter Patienten vom Respirator (Weaning) zunehmend an Bedeutung. Vor diesem Hintergrund wurden ab den 1980iger Jahren Zentren geschaffen, die speziell auf das Weaning von Patienten von der maschinellen Beatmung ausgerichtet waren.

In dem Artikel werden die strukturelle Entwicklung sowie die Ergebnisse aus den letzten zehn Jahren (2006 – 2015) des Weaningzentrums der Universitätsmedizin Greifswald dargestellt. Dazu wurden die Daten von 616 Patienten ausgewertet. Über die Jahre zeigt sich eine Verschiebung der zur Beatmung führenden Grunderkrankung, wobei der Anteil kardiochirurgischer Patienten rückläufig war und die Patienten mit Pneumonie/Sepsis zugenommen haben. Im Zeitverlauf haben die Tage mit Beatmung vor Aufnahme (p = 0,004) als auch die Beatmungstage im Weaningzentrum (p = 0,02) signifikant abgenommen. Ungeachtet des hohen APACHE-II-Scores bei stationärer Aufnahme konnte der Prozentsatz erfolgreich entwöhnter Patienten von 62,7 % (2006 – 10) auf 77,3 % (2011 – 2015) signifikant gesteigert werden (p < 0,001). Der Anteil der Patienten mit invasiver Beatmung bei Entlassung konnte signifikant von 16,4 % auf 9,6 % (p < 0,001) gesenkt und auch der Anteil der während des stationären Aufenthaltes verstorbenen Patienten von 20,9 % auf 13,0 % signifikant reduziert werden (p < 0,001). Das 1-Jahres-Überleben der erfolgreich entwöhnten Patienten lag bei 72 Prozent.

Die Ergebnisse bei der Betreuung der Patienten im Weaningzentrum Greifswald bewegen sich auf vergleichbarem Niveau anderer deutscher Weaningzentren.