bluuebunny/crossref_metadata_2025 huggingface dataset:
A Noval Solar Simulator to Explore Envirnoment Impacts On Panel Efficiency
Authors: Zafar Shaheer Ahmad , Jaffri Nasif Raza , Abid Toseef , Abrar Usama
Published: June 2024

The paper provided a complete hardware design for a solar simulator for versatile environmental conditions. These conditions include shading, humidity, dust, and temperature. In this work, the solar simulator was designed and fabricated to analyze the performance of PV panels with and without air cooling mechanisms in indoor tests. The halogen bulbs with built-in reflector support by the steel structure holder act as natural sunlight. The challenge for a solar simulator is stable uniform solar radiation and illumination. The uniform solar radiation of 7,575 candela was measured in the test area. Several units of PV panels were tested on variable environmental conditions. The air-cooling mechanism with a speed of 200 km/h decreases the surface PV panels with an air-cooling mechanism decreased by 2.3 ˚C. This increases the efficiency of the panel by 6.11 % of the maximum power output based on different fixed solar radiation. They have also compared it by hardware and by simulation method. An overall method and procedure of the measurement by the solar simulator are discussed and proposed
EFEKTIFITAS PROGRAM ONE DAY BOARDING DALAM MEMBENTUK KARAKTER ISLAMI SISWA SMP dan MTS MUHAMMADIYAH DI KABUPATEN SIDOARJO
Authors: Wijayanto Anang
Published: June 2024

Penelitian ini bertujuan untuk mengetahui efektivitas program One day Boarding dalam membentuk dan memperkuat karakter Islami siswa SMP dan MTS Muhammadiyah di kabupaten Sidoarjo. Pendidikan merupakan hal terpenting dalam kemajuan suatu bangsa dan merupakan salah satu faktor utama dalam mewujudkan kehidupan masyarakat yang bernilai dan beradab. Nilai-nilai yang dimaksud adalah nilai-nilai kehidupan yang sesuai dengan norma agama dan norma bangsa guna memantapkan karakter kehidupan masyarakat pada umumnya, sehingga sejak dini semua program pendidikan hendaknya diarahkan pada proses penguatan karakter keislaman peserta didik. meliputi pengetahuan moral, perasaan moral, dan tindakan moral. Kuatnya arus disrupsi budaya masyarakat di era revolusi industri 4.0 menjadi tantangan tersendiri dan memerlukan upaya yang luar biasa. Era ini mengandalkan rekayasa intelektual kecerdasan buatan dan internet of things serta big data yang membuka ruang dan peluang tak terbatas bagi siapa pun untuk mengakses informasi dan berinteraksi secara virtual dengan cepat dan mudah serta biaya yang sangat murah. Disrupsi masyarakat yang muncul tidak hanya menyangkut aspek ekonomi dan teknologi tetapi juga aspek politik, sosial, budaya, moral bahkan agama. “One Day Boarding” merupakan program yang dirancang untuk memperkuat karakter siswa berdasarkan nilai-nilai Al-Qur'an dan Sunnah Nabi Muhammad SAW. Penelitian ini merupakan penelitian kualitatif deskriptif sehingga pengumpulan data penelitian dilakukan melalui observasi, wawancara dan dokumentasi. Hasil penelitian menunjukkan bahwa program one day barding cukup efektif dalam menumbuhkan dan memperkuat karakter keislaman siswa SMP Muhammadiyah dan MTS di kabupaten Sidoarjo.
METODE PENDIDIKAN ISLAM PERSPEKTIF SHOLEH FAUZAN (TELAAH KITAB SYARAH HADIS JIBRIL)
Authors: Suhri Ahmad , Purnama Satya Indra
Published: June 2024

Penelitian ini membahas tentang: 1. Bagaimana telaah kitab Syarah Hadis Jibril karya Sholeh Fauzan?, 2. Bagaimana metode pendidikan Islam dalam perspektif Sholeh Fauzan dalam kitab Syarah Hadis Jibril?, dan 3. Bagaimana relevansi pendidikan Islam dalam perspektif Sholeh Fauzan pada pendidikan di Indonesia? Pada penelitian ini penulis menggunakan metode penelitian kualitatif dengan pendekatan studi pustaka, dimana penulis menggunakan beberapa literatur berupa kitab, artikel, atau yang semisalnya baik online maupun offline yang menjadi sumber data pada penelitian ini. Sumber data pada penelitian ini dibagi menjadi dua yaitu sumber data primer yaitu kitab Syarah Hadis Jibril dan sumber data skunder yaitu beberapa kitab, artikel atau yang lainnya yang memiliki kaitan dengan pembahasan yang sedang diteliti. Setelah melakukan penelitian dari kitab Syarah Hadis Jibril dengan menggunakan metode kualitatif tersebut maka ditemukanlah beberapa hasil penelitian diantaranya adalah: 1. Isi kandungan kitab Syarah Hadis Jibril meliputi (Metode Pendidikan Islam, Materi Pendidikan Islam, kurikulum pendidikan Islam, dan Akidah dan akhlak). 2. Metode Pendidikan Islam, meliputi (Metode Tanya Jawab dan Metode Teladanan). 3. Relevansi Pendidikan Islam Perspektif Sholeh Fauzan di Indonesia, meliputi (Pendidikan Islam di Indonesia, Metode Pendidikan Islam di Indonesia, Kurikulum Pendidikan di Indonesia) kesimpulannya bahwa ketiga temuan tersebut sangat relevan jika diterapkan pada pendidikan Islam di Indonesia.
Agensi Pasif: Refleksivitas dan Rasionalitas Perempuan Perokok di Yogyakarta
Authors: Haq Ahmad Nadhif , Sujibto B.J.
Published: June 2024

This article analyzes how young women smokers defend themselves and perpetuate their smoking activity in an environment that rejects it through discursive understanding as the basis for their actions. In addition, this study discusses how women smoke and take into account smoking activity, social aspects, and physical aspects around it. The theoretical approach used is the agency theory of ​​Anthony Giddens which deeply considers the aspects of managed reflexivity. This theory underlines that a continuous flow or stream of acts is inherently constructed by a process of rationalizing actions to underlie the agent's actions through reflexive monitoring. This study uses qualitative methods to obtain in-depth information from primary sources, namely smoking women in Yogyakarta. To support primary data, observation and documentation are used as secondary data sources. This article scrutinizes (1) women as social agents reflect the surrounding norms, smoking ethics, their body's acceptance of smoking, and their health risks, (2) women smokers rationalization their actions with a practical and discursive basis include the history of smoking women, gender equality, discourse on pharmaceutical interests, and culturally expressed self-freedom, and (3) smoking women are passive agents, namely agents who act within the limits of the structure but have power over themselves. to express themselves.
Chasing Dragons in the Dragon's Land: A Convoluted Struggle with Drugs and Deviance in Modern China
Authors: Haider Aftab , Ali Ashraf , Zubair Muhammad
Published: June 2024

This paper discusses the war against drugs in China – from historical Opium Wars to contemporary issues with synthetic narcotics. This paper will thoroughly delve into the intricate interactions of governmental policies, public health initiatives, and societal changes. The drug scenario in China, previously opium-centric is now a cocktail of different drugs such as designer and misuse of prescription drugs.. We will analyze reasons for this change, which include social and economic pressures as well as impact of the digital world. This paper will focus on different ways through which China has been addressing the drug problem ranging from harsh crackdowns to more lenient harm reduction approaches that emphasize treatment and rehabilitation. We will assess how well these policies have worked, emphasizing successes, areas that need enhancement and any inadvertent consequences. But dealing with drug issues is not only about the rules; it’s also about smart healthcare decisions. Healthcare interventions, educational programs, and community outreach efforts designed to address the issue at its roots. These challenges include eliminating the stigma of using drugs, improving access to drug treatment, and mainstreaming harm reduction in discussions. It supports the development of policies that are flexible and based on evidence, focused more on public health as well as with law enforcements. This is the only approach that will allow us to deal with the problem properly, not just running after the dragon and making sure its shadow does not cast itself over a bright image of this nation.
MENINGKATKAN PENGEMBANGAN DIRI GURU PENDIDIKAN AGAMA ISLAM (PAI) SEBAGAI IMPLEMENTASI TEORI DINAMIS-PROGRESIF DI SEKOLAH DASAR
Authors: Ambarwati Fera Nofiana
Published: June 2024

Abstract: This paper tries to reveal why PAI teachers do not have the will to develop hemselves. PAI teachers not only fulfill the teaching obligation, but also must have good self-quality and wish to advance. But until now there are still many PAI teachers who do not want to develop and resign themselves to the situation. As a result, the results of education have not progressed. Students who are supposed to think ahead, become infected by the teacher's attitude which is resigned and does not want to develop. From this research it was found that the biggest cause of the attitude of teachers who do not want to develop themselves is there is no desire to continue learning. Based on these findings, researchers used a dynamic-progressive theory to improve the self-development of PAI teachers who would later change the mindset of PAI teachers to continue learning and developing.
Abstrak: Tulisan ini mencoba mengungkap mengapa guru PAI tidak memiliki keinginan untuk mengembangkan diri. Guru PAI tidak hanya memenuhi kewajiban mengajar, tetapi juga harus memiliki kualitas diri yang baik dan berkeinginan untuk maju. Namun sampai saat ini masih banyak guru PAI yang tidak mau berkembang dan pasrah dengan keadaan. Akibatnya, hasil pendidikan tidak mengalami kemajuan. Siswa yang seharusnya berpikir ke depan, tertular oleh sikap guru yang pasrah dan tidak mau berkembang. Dari penelitian ini ditemukan bahwa penyebab terbesar dari sikap guru yang tidak mau mengembangkan diri adalah tidak adanya keinginan untuk terus belajar. Berdasarkan temuan tersebut, peneliti menggunakan teori dinamis-progresif untuk meningkatkan pengembangan diri guru PAI yang nantinya akan mengubah pola pikir guru PAI untuk terus belajar dan berkembang.
PENGEMBANGAN DESAIN PEMBELAJARAN PADA KELAS PROFESIONAL PGMI MENGGUNAKAN GOOGLE CLASSROOM
Authors: Septantiningtyas Niken
Published: June 2024

Abstract: This research is a development research with the aim of designing the development of learning design in professional classes using Google classroom and group learning methods. The development of this design was tested by the feasibility test outlined by BSNP, namely regarding the eligibility of content, feasibility of presentation, and achievement of learning outcomes obtained an average percentage of 86.73% suitable to be applied in professional classes. In the professional class Google Classroom is very helpful in the lecture process so that all tasks can be completed in a timely manner and can be accessed from anywhere and anytime.
 
Abstrak: Penelitian ini adalah penelitian pengembangan yaitu dengan tujuan merancang pengembangan desain pembelajaran pada kelas profesional menggunakan google classroom dan metode pembelajaran berkelompok. Pengembangan desain ini diuji dengan uji kelayakan yang di jabarkan oleh BSNP yaitu mengenai kelakan isi, kelayakan penyajian, dan ketercapaian hasil pembelajaran didapatkan hasil prosentase rata-rata sebesar 86,73 percent layak untuk di terapkan dalam kelas profesional. Pada kelas profesional google clasroom sangat membantu dalam proses perkuliahan sehingga semua tugas dapat diselesaikan secara tepat waktu dan dapat diakses dari manapun dan kapanpun.
The Influence of Creative Problem-Solving Learning Models on Students' Creative Thinking Skills related Temperature and Heat
Authors: Baharuddin Fitriani , Nurazmi  , Fiskawarni Tri Hastiti
Published: June 2024

One of the skills needed to face the 21st century is creative thinking. The aim of this research is to find out whether there is a significant difference between the creative thinking skills of students who are taught using the creative problem-solving learning model and those taught using the conventional model. This type of research is quasi-experimental, with the research design used being a nonequivalent control group. The subjects in this research are all students in class XI MIA SMAN 14 Maros, with the sample being class XI MIA 2 as the experimental class and class controls, each numbering 34 people. The research instrument used was a creative thinking skills test instrument on temperature and heat materials. The results of this research show a difference in the average score of students' creative thinking abilities between the experimental class and the control class, namely 33.49 in the experimental class and 28.29 in the control class. From the results of the hypothesis test, it can be seen that there are differences in the creative thinking skills of experimental class and control class students using a significance level of α = 0.05. Based on the results of this research, it can be concluded that the physics creative thinking ability of students taught using the creative problem solving learning model is higher than the physics creative thinking ability of students taught using the conventional learning model.
Sağlık sigortası sektöründe poliçe maliyetlerinin kârlılık çerçevesinde analizi
Authors: Terzi Ahmet , Değirmencioğlu Pınar Tuğba
Published: June 2024

Sigorta sektörü maliyetlerinin analizi, şirketlerin kârlılığını etkileyen faktörleri anlamak adına kritik bir rol oynamaktadır. Sigorta sektöründe faaliyet gösteren şirketlerin mali yeterliliği, finansal performansı ve kârlılığı analiz eden literatürde birçok çalışma olmasına karşın, sigorta maliyet analizine ilişkin ise sadece birkaç çalışma bulunmaktadır. Bu çalışma; sağlık sigortalarına ilişkin yapılan maliyet analizleri ile literatüre katkıda bulunmayı amaçlanmaktadır. Çalışma, Türkiye Sigorta, Reasürans ve Emeklilik Şirketleri Birliği’nin web sayfasında yayımlanan sağlık sigorta şirketlerinin 2018-2022 yılları arasındaki verilerini kapsamaktadır. Öncelikle ilgili yıllar arasındaki toplam poliçe sayıları ve prim üretimleri ve sağlık sigortası branşında maliyet kalemleri değerlendirilip analiz edilmiştir. Çalışmada kullanılan veriler yardımıyla birim poliçe maliyetleri, poliçe edinme maliyetleri ile ortalama poliçe maliyeti hesaplanmıştır. Ayrıca teknik kâr ve bilanço kârları, poliçe maliyetleri ile karşılaştırılarak analiz gerçekleştirilmiştir. Çalışma sonucunda; 2021 yılı haricinde teknik kârda artış eğilimi görülürken aynı dönemlerde poliçe maliyetlerinde ise artışın olmadığı görülmüştür. 2019 yılında bir önceki yıla göre teknik kârda %52’lik artış gerçekleşirken poliçe maliyetinde ise %16’lık düşüş gerçekleştiği tespit edilmiştir. Bir diğer tespit ise, 2021 yılında ise bir önceki yıla göre teknik kârda %6’lık düşüş gerçekleşirken, poliçe maliyetinde ise %97’lik artışın gerçekleştiğidir. 2018-2022 yılları arasında bilanço kârlarında artış eğilimi görülürken, aynı dönemlerde poliçe maliyetlerinde ise artışın olmadığı görülmüştür.
Doğal ve kültürel mirasın korunması bağlamında bir araştırma: Nevşehir ilinin anıt ağaçları
Authors: Yıldız Altın Kübra , Çolakoğlu Mustafa Hilmi
Published: June 2024

Nevşehir, doğal ve kültürel miraslar açısından oldukça zengin bir bölgedir. Peri Bacaları ile ünlü olan bölgede anıt ağaç niteliğindeki doğal mirasların da değeri çok önemlidir. Bu çalışmada Nevşehir İlinin Anıt Ağaçları başlıklı projenin sonuçları hakkında bilgi verilerek kazanımların bilimsel birikime olan yaygın etkisinin artırılması ve tüm kültürel miras paydaşlarının konuya dikkatlerinin çekilmesi amaçlanmaktadır.
Nevşehir’de anıt ağaçlar konusundaki çalışmaların azlığı, bu çalışmalarda sahada derleme yöntemlerinin kullanılmaması, kaynak kişiler ile derinlemesine görüşülmemesi, anıt ağaçlar özelinde kültürel mirasa yönelik tespit çalışmalarının henüz tamamlanmamış olması ve yerel halkın bu konudaki düşük farkındalık düzeyi çalışmanın çıkış noktalarıdır. Halkbiliminin alan araştırması yöntemlerine bağlı olarak sahadan derlenen malzeme üzerinde temellendirilen çalışmanın yöntemini katılımcı gözlem, dışarıdan gözlem, kaynak kişilerden yararlanma, derinlemesine görüşme ve arşiv taraması oluşturmaktadır.
Çalışmada geçmişten günümüze ağaçlar etrafında şekillenen sözlü kültür belleğinin tespit edilerek bu bilgi birikiminin koruma altına alınması hedeflenmektedir. Bu amaçla çalışma, boyutsal ve görsel nitelikli anıt ağaçların yanı sıra özellikle kültürel anıt ağaçlara odaklanmaktadır. Yapılan saha araştırmasında kırk beş adet anıtsal nitelikli ağaç tespit edilmiştir. Sahadan elde edilen veriler, harita üzerinde sayısallaştırılarak dijital ortama aktarılmış ve bütüncül bir bakış açısıyla değerlendirilmiştir.
The place and role of the Oscar Film Award in Russian cinema
Authors: Shumov Maksim Vladimirovich
Published: June 2024

The purpose of the study is to identify the place and role of the Oscar film Award by the American Academy of Motion Picture Arts and Sciences in the Russian film community. The article reveals the aspects of the Oscar Film Award in the context of the global recognition of the professional merits of Russian cinematographers and their works. The focus is not only on the quantitative approach, but also on the qualitative one. It is important for the author to trace the nominations of the film award, the years of application, the directors who repeatedly apply, as well as the opinions of critics and viewers of the submitted films in order to reveal the comprehensive role of this film award in the career of domestic cinematographers, as well as their status in the world of cinema. The scientific novelty of the research lies in the actualization of the role of the Oscar film Award in relation to Russian cinema and the justification of a clear analytical approach to films and directors claiming to be the winner of the most prestigious film award in the world. As a result of the study, it was revealed that Russia (including the Soviet period of its existence) was represented at the Oscar Film Awards from 1943 to 2023. During this period, 64 films were officially submitted from our country to participate in various film award nominations. Of these, 29 became the official nominees of the film award in 7 nominations. The most successful year, in terms of Oscar nominations, was 2008, and the decade was the 1990s. The most nominated directors were Nikita Mikhalkov (6 applications, 3 nominations, 1 win) and Alexander Petrov (4 applications, 4 nominations, 1 win). It has also been revealed that many filmmakers around the world consider this film award to be politicized and biased. However, this does not exclude the enormous influence of this award, as well as its laureates, on the world film community.
Analysis of the effectiveness of ML algorithms for emotion recognition, taking into account prosodic and spectral features
Authors: Zavrumov Zaur Aslanovich , Goncharova Oksana Vladimirovna , Levit Alina Aleksandrovna
Published: June 2024

The aim of the study is to determine the optimal classifier for identifying an emotional state based on the results of a comparative analysis of the effectiveness of various machine learning algorithms based on a combination of prosodic and spectral features. The scientific novelty consists in the application of ML algorithms in the recognition of emotionally marked speech of North Caucasian bilinguals in the problem of binary classification of the presence or absence of an accent with the determination of the optimal combination of universal prosodic and spectral features. During the study, an experimental corpus of speech of representatives of three ethnic groups (Russians, Kabardians and Armenians) was created with an annotation of the degree of accent, prosodic (94 signs) and spectral (74 signs) characteristics were extracted from speech signals, a comparative analysis of the effectiveness of machine learning algorithms (logistic regression, k-nearest neighbors, the method of support vectors, decision trees) in the problem of binary classification of the presence/absence of emphasis. The results of the study showed that at the syllabic level, the most effective is the decision tree model with combined features, and at the phrasal level, the k-nearest neighbor model with prosodic features. Universal prosodic features that form the basis of the "language model of emotions" were identified, as well as typological differences in their implementation, reflecting the influence of the native language on the emotional speech of bilinguals.
Preclinical Safety Assessment of Antineoplastic Agents Based on Live Non-Pathogenic Enteroviruses
Authors: Sivak K. V. , Stosman K. I. , Kalinina E. Yu. , Lyubishin M. M. , Orshanskaya Ya. R. , Savateeva-Lyubimova T. N. , Kazakova S. B. , Fedoseeva D. M. , Nazarov A. S. , Radion E. I. , Yudin S. M. , Keskinov A. A. , Makarov V. V. , Yudin V. S. , Zheltukhin A. O. , Vorobyev P. O. , Kochetkov D. V. , Ilyinskaya G. V. , Lipatova A. V. , Chumakov P. M.
Published: June 2024

INTRODUCTION. Developing novel medicines based on non-pathogenic enterovirus strains exhibiting oncotropic and oncolytic properties represents an up-to-date and safe approach to complex cancer treatment and postoperative metastasis prevention. Safety pharmacology studies are a necessary step in the preclinical development of medicinal products.

AIM. The study aimed to investigate the single and repeated-dose general toxicity, local tolerance, safety pharmacology, and pyrogenicity of medicinal products based on non-pathogenic LEV4, LEV7, LEV8, LEV14, and Russo enterovirus strains as part of preclinical safety studies.

MATERIALS AND METHODS. The study used medicinal products of highly purified group A, B, and C enteroviruses at a titre of 2×107–5×108 CPD50/mL (CPD50 is a cytopathogenic dose of the virus causing 50% cell lysis) and normal saline as a diluent. The viruses were propagated in Vero cells. The safety study used 220 male and female BALB/c mice, 440 male and female Wistar rats, and 18 male Soviet chinchilla rabbits. The study animals received an intravenous dose of 1×105 or 1×106 CPD50/animal once (single-dose toxicity) or weekly for 90 days (repeated-dose toxicity). Clinical examination, laboratory testing, and necropsy were performed on Days 45 and 91 of the experiment. Statistical data processing was performed using Prism 8.0 software (GraphPad Software, Inc., USA).

RESULTS. Upon single administration of each of the five enterovirus medicinal products to mice and rats, the authors observed complete survival, upward trends in body weight gain, and no gross or histopathological changes in the brain, spleen, liver, kidneys, lungs, or at the injection site. Upon repeated administration at the study doses, the medicinal products caused no functional changes in the organs and systems. All the studied parameters were within the normal physiological ranges for male and female rats. Histopathological examination revealed no pathological changes or specific cytolytic and/or cytopathic effects. No local irritation was observed. None of the investigational medicinal products showed pyrogenicity.

CONCLUSIONS. The obtained preclinical results demonstrate the safety of antineoplastic agents based on live non-pathogenic LEV4, LEV7, LEV8, LEV14, and Russo enteroviruses.
I spy something #invisible: Using Instagram to help learners understand second language invisible culture
Authors: Blattner Géraldine , Dalola Amanda , Roulon Stéphanie
Published: June 2024

French-language textbooks have long faced criticism for their limited use of authentic resources and their failure to meaningfully incorporate cultural elements into language teaching, letting foreign language learners struggle to grasp the non-literal aspects of language, known as the “invisible culture.” These hidden cultural components encompass beliefs, values, social norms, and non-verbal cues, influencing communication and language use. Experienced language users may take these elements for granted, making them challenging for learners to grasp without adequate exposure to French. Understanding these hidden cultural elements is essential for successful language acquisition and cross-cultural communication, enabling learners to genuinely and authentically interpret and express themselves. Without positive evidence of a concept’s culturally specific values, learners must rely on cultural knowledge from their first language/culture, which results in the direct transfer of cultural assumptions which hinders their ability to make authentic sense of the target language. Taking inspiration from the Cultura project, this study uses the multiliteracies framework to bridge the gap between first and second-language intercultural representations, helping learners develop semantic aspects of cross-cultural literacy through visualization tasks using Instagram, a photo-based social media platform. Intermediate-level French students provided written impressions of three culturally specific word pairs: snack/goûter, suburb/banlieue, and freedom/liberté. They searched for these concepts on Instagram, selected images that best represented their understanding, and created e-posters. Participants then analyzed and compared these e-posters across languages, refining their definitions during discussions. This approach successfully developed certain semantic aspects of the invisible culture within the target language, highlighting the benefits of exposing learners to diverse text types.
La Unión de Cooperativas Agrícolas Algodoneras Limitada (UCAL). Estrategias de consolidación y pervivencia en una economía regional cambiante (1934-1984)
Authors: Moglia Leandro Eduardo
Published: June 2024

La Unión de Cooperativas Agrícola Algodoneras Limitada surgió en 1934 y como consecuencias de diversas causas: crisis del año treinta, huelga algodonera del Chaco, entre otras. Fue la principal institución de referencia de la región por más de 50 años. Se desarrolló vinculada íntimamente a la producción algodonera y apostó a su industrialización. UCAL, constituyó una gran empresa regional que incursionó en cuestiones financieras y el negocio de la exportación. Es objetivo de este trabajo, analizar la trayectoria institucional de UCAL durante un período de 50 años, durante el cual las políticas macroeconómicas fueron cambiando generando grandes transformaciones en la institución.
Analisa Biaya Pekerjaan Pemancangan CCSP di Hulu Bendung Talang, Kabupaten Jember
Authors: Yanuar Setiyo Ferdi , Ahmad Hilfi Harisan , Dewi Ilanka Cahya
Published: June 2024

Proyek pemancangan CCSP pada hulu bendung Talang ini terletak di Kabupaten Jember. Pada pekerjaan ini dikerjakan oleh sub-kontraktor alat berat yang sekaligus memiliki pabrik precast. Dalam jurnal ini dibahas 2 item pekerjaan, yakni pekerjaan mobdemob dan pemancangan CCSP. Hal ini dibahas secara bersamaan karena alat berat yang didatangkan ke lokasi proyek membutuhkan item pekerjaan mobdemob. Selama pekerjaan berlangsung, terjadi keterlambatan yang disebabkan oleh main kontraktor. Dalam penelitian ini akan dibahas biaya yang dikeluarkan oleh pihak sub-kontraktro menurut perhitungan yang mengacu pada permen PUPR 8 tahun 2023. Kemudian biaya tersebut akan dibandingkan dengan nilai kontrak yang disepakati oleh sub-kontraktor dan main kontraktor. Dari hsail perbandingan ini didapatkan angka keuntungan sebesar Rp.24,385,424.
Analisis Sebaran Nilai Salinitas dan Suhu Permukaan Laut di Perairan Ketingan Kabupaten Sidoarjo
Authors: Sinatrya Andra Fadil , Zainab Siti
Published: June 2024

Perairan Ketingan berada di pesisir timur laut Kabupaten Sidoarjo, tepat di sebelah Kabupaten Bangil. Pola sebaran salinitas dan suhu permukaan laut di perairan Ketingan dipengaruhi oleh interaksi tersebut. Berdasarkan landasan tersebut, penelitian diharapkan dapat menskrining sebaran nilai salinitas dan suhu permukaan laut tahun 2019 hingga 2023 di Ketingan dengan memanfaatkan simbolisme satelit Landsat 8. Model algoritme guna analisis salinitas citra ialah panjang gelombang Band_2, dengan persamaan logaritma y = -41.72ln(x) - 73.445 dan derajat determinasi R2 = 0.1442. Ini adalah hasil dari algoritma pemodelan. sedangkan persamaan linier y = 321,53x + 27,214 dan derajat determinasi R2 = 0,0346 untuk suhu permukaan laut. Hasil analisis dari uji ANOVA untuk nilai salinitas H1 diterima maka artinya ada perbedaan Nilai Salinitas insitu dengan Nilai Salinitas citra satelit Landsat 8 tahun 2019 sampai 2023. Sedangkan untuk suhu permukaan laut H1 diterima sehingga berarti terdapat ketidaksamaan yang signifikan diantara SPL insitu dengan SPL citra satelit tahun 2019 sampai 2023.
Pyroptosis in Spinal Cord Injury: Implications for Pathogenesis and Therapeutic Approaches
Authors: Gu Guangjin , Yu Huaqi , Zou Huishuang , Kou Wenjuan , Zhang Pingping , Gu Guangjie , Lu Jie , Shi Weihan , Chu Pengcheng , Zhang Yaning , Sun Guangwei , Shang Jun
Published: June 2024

Traumatic spinal cord injury (SCI) is a serious disease of the central nervous system. Aside from the limited intrinsic regenerative capacity of neurons, complex microenvironmental disturbances can also lead to further cellular damage and growth inhibition. Programmed cell death regulated by pyroptosis has an important role in the pathogenesis of SCI. While there has been a wealth of new knowledge regarding cellular pyroptosis, a detailed understanding of its role in SCI and possible therapeutic strategies is still lacking. This review summarizes current advances in the regulatory role of pyroptosis-regulated cell death and inflammasome components in the inhibitory microenvironment following SCI, as well as recent therapeutic advances.
REST Promotes Autophagy in Gastric Cancer by Transcriptionally Activating FABP6 to Inhibit the Akt/mTOR Signaling Pathway
Authors: Luo Jing , Yu Hongmei , Yuan Zhen , Tang Wenqing , Wang Chen
Published: June 2024

Background: Gastric cancer (GC) is a leading cause of cancer-associated death worldwide. Its molecular mechanisms, especially concerning autophagy and various signaling pathways, are not fully understood. Fatty Acid Binding Protein 6 (FABP6) and RE1 Silencing Transcription Factor (REST) emerge as potential key players in this context. This study sought to analyze the functional relationship of FABP6 and REST concerning autophagy and their implications on the Akt/mTOR signaling pathway within GC cells. Methods: A comprehensive bioinformatics approach was used to identify key prognostic markers in GC. The effects of FABP6 and REST on autophagy along with Akt/mTOR signaling pathways were analyzed by techniques including Western blotting (WB), flow cytometry, Transwell assay, dual luciferase reporter assay, and others. Results: FABP6 was identified as overexpressed in GC, linked with poor prognosis. FABP6 silencing reduces GC cell proliferation, induces S- and G2-phase arrest, and downregulates cyclins CDK2 and CDK4. It also inhibited GC cell invasion/migration and autophagy, effects that were counteracted by MG132. When combined with PI3K inhibitor LY294002c, FABP6 knockdown showed synergistic anti-proliferative effects, modulating the Akt/mTOR pathway. Besides, the transcription factor REST has been shown to directly regulate FABP6 expression, affecting autophagy and the Akt/mTOR signaling pathway in a FABP6-dependent manner. Conclusions: REST positively regulates autophagy and negatively affects the Akt/mTOR signaling pathway in GC cells in a FABP6-dependent manner, providing valuable insights into regulatory networks involving FABP6 and REST.
SMP30 Interacts with ROCK1 to Inhibit HCC Invasiveness by Effecting the Epithelial-Mesenchymal Transition
Authors: Zheng Shunxin , Mo Zhijing , Lv Zhilue , Zhuang Yuan , Zhou Sufang
Published: June 2024

Background: The senescence marker protein 30 (SMP30) is a calcium-binding protein whose expression decreases with age, and is closely associated with hepatocellular carcinoma (HCC) development. The primary goal of this study was to examine the mechanistic effect of SMP30 on HCC migration and invasion. Methods: Bioinformatic and immunohistochemical approaches were used to examine the expression of SMP30 in HCC tissues and its relationship to patient survival. We investigated the effects of SMP30 expression on HCC cell proliferation, migration, invasion, and cell cycle dynamics. cDNA microarray technology was used to determine the gene expression profile of SK-Hep-1 cells following recombinant SMP30 overexpression to identify genes downstream of SMP30 that regulate HCC cell migration and invasion. We identified SMP30 interacting proteins by affinity purification-mass spectrometry (AP-MS) and co-immunoprecipitation/western blotting (COIP-WB). Results: SMP30 expression was lower in HCC tissues compared with normal liver tissues, and its expression positively correlated with overall survival in HCC patients. Additionally, SMP30 overexpression effectively blocked the migratory and invasive properties of SK-Hep-1 cells, but did not affect either proliferation rates or cell cycle. cDNA microarray results confirmed that many of the differentially expressed genes identified are involved in the process of epithelial-mesenchymal transition (EMT). AP-MS and COIP-WB experiments confirmed that Rho-associated protein kinase 1 (ROCK1) interacts with SMP30 in SK-Hep-1 cells, and ROCK1 is known to intimately regulate the EMT process. Conclusion: SMP30 inhibits HCC metastasis by influencing the expression of EMT-related proteins after interacting with ROCK1.
Deep Brain Stimulation Mechanisms in Parkinson's Disease: Immediate and Long-Term Effects
Authors: Pei Honglong , Wu Zhenghan , Ma Li , Wang Jun , Li Jinghui , Geng Xin , Zou Yanghong , Zhang Mou , Qi Renli , Yu Hualin
Published: June 2024

Deep brain stimulation (DBS) is a common therapy for managing Parkinson’s disease (PD) in clinical practice. However, a complete understanding of its mode of action is still needed. DBS is believed to work primarily through electrical and neurochemical pathways. Furthermore, DBS has other mechanisms of action. This review explores the fundamental concepts and applications of DBS in treating PD, including its mechanisms, clinical implications, and recent research.
An Overview of Computational Coronary Physiology Technologies Based on Medical Imaging and Artificial Intelligence
Authors: Li Bin , Chen Huaigang , Wang Hong , Hong Lang , Yang Liu
Published: June 2024

This article reviews four new technologies for assessment of coronary hemodynamics based on medical imaging and artificial intelligence, including quantitative flow ratio (QFR), optical flow ratio (OFR), computational fractional flow reserve (CT-FFR) and artificial intelligence (AI)-based instantaneous wave-free ratio (iFR). These technologies use medical imaging such as coronary angiography, computed tomography angiography (CTA), and optical coherence tomography (OCT), to reconstruct three-dimensional vascular models through artificial intelligence algorithms, simulate and calculate hemodynamic parameters in the coronary arteries, and achieve non-invasive and rapid assessment of the functional significance of coronary stenosis. This article details the working principles, advantages such as non-invasiveness, efficiency, accuracy, limitations such as image dependency, and assumption restrictions, of each technology. It also compares and analyzes the image dependency, calculation accuracy, calculation speed, and operation simplicity, of the four technologies. The results show that these technologies are highly consistent with the traditional invasive wire method, and shows distinct advantages in terms of accuracy, reliability, convenience and cost-effectiveness, but there are also factors that affect accuracy. The results of this review demonstrates that AI-based iFR technology is currently one of the most promising technologies. The main challenges and directions for future development are also discussed. These technologies bring new ideas for the non-invasive assessment of coronary artery disease, and are expected to promote the technological progress in this field.
In-Hospital Adverse Events of Pheochromocytoma-Induced Takotsubo Syndrome: A Literature Review and Cluster Analysis of 172 Cases
Authors: Xu Mei , Guan Qianglin , Liu Tianmin , Huang Yuxi , Pan Cunxue , Luo Liyun , Tang Wenyi , Xu Junwei , Huang Hsi , Xiao Li , Liu Kan , Chen Jian
Published: June 2024

Background: Pheochromocytoma-induced takotsubo syndrome (Pheo-TTS) significantly increases the risk of adverse events for inpatient. The early identification of risk factors at admission is crucial for effective risk stratification and minimizing complications in Pheo-TTS patients. Methods: We conducted a systematic review combined with hierarchical cluster and feature importance analysis of demographic, clinical and laboratory data upon admission, alongside in-hospital complication data for Pheo-TTS patients. We analyzed cases published in PubMed and Embase from 2 May 2006 to 27 April 2023. Results: Among 172 Pheo-TTS patients, cluster analysis identified two distinct groups: a chest pain dominant (CPD) group (n = 86) and a non-chest pain dominant (non-CPD) group (n = 86). The non-CPD group was characterized by a younger age (44.0 ± 15.2 vs. 52.4 ± 14.4, p < 0.001), a higher prevalence of neurological/psychiatric disorders (53.5% vs. 32.6%), and increased presentation of dyspnea (87.2% vs. 17.4%), pulmonary rales (59.3% vs. 8.1%), and tachycardia (77.9% vs. 30.2%). Additionally, they exhibited more atypical takotsubo syndrome (TTS) imaging phenotypes (55.8% vs. 36.5%, all p < 0.05). The non-CPD group experienced more than a 2-fold increase for in-hospital adverse events compared to the CPD group (70.9% vs. 30.2%, p < 0.001). After adjusting for confounding factors, the absence of chest pain (odds ratio [OR] = 0.407, 95% confidence interval [CI] 0.169–0.979, p = 0.045), the presence of abdominal symptoms (OR = 3.939, 95% CI 1.770–8.766, p = 0.001), pulmonary rales (OR = 4.348, 95% CI 1.857–10.179, p = 0.001), and atypical TTS imaging phenotype (OR = 3.397, 95% CI 1.534–7.525, p = 0.003) remained as independent predictors of in-hospital complications. Conclusions: Clinical manifestations and imaging features at admission help to predict in-hospital complications for Pheo-TTS patients.
Negative phenomena of the everyday life of the youth of the Ural region in the second half of the 19th — early 20th centuries
Authors: Perebeynos Artem , Ptashko Tatyana , Tsilitsky Vitaly , Mulyukova Asel , Moiseeva Elena
Published: June 2024

The article highlights the issues of negative phenomena in the everyday life of working youth in the Urals in the second half of the 19th - early 20th centuries. On the basis of archival documents discovered by the authors, the reasons and tendencies of deviant, delinquent behavior among the youth of the Urals on the territory of the Orenburg, Ufa, Perm and Vyatka provinces are revealed: drunkenness, robbery, theft. It was the young generation that took a special place in the dynamics of crime; the increase in the number of violations of the law was among girls. The manifestation of negative sides led to the emergence of new measures to combat them, including those of a repressive nature.
Kaluga bureaucracy on the pages of the provincial gazette (1852—1867)
Authors: Sergienko Natalia , Shcherbakova Natalia , Sibiryaev Alexey , Trikhina Irina
Published: June 2024

The article reveals the image of a provincial official of Russia in the middle of the 19th century on the basis of publications in the provincial gazette published in the Kaluga province. The article pays special attention to the issues of material support of civil servants of lower ranks, the reasons for their movement in the service and gratuitous encouragement.
Evolution of Fluvial Landscapes during the Eocene-Oligocene Transition in Central North America: Reconstructions from Toadstool Geologic Park, Nebraska, U. S. A.
Authors: Chang Queenie , Fernandes Anjali , Hren Michael , Smith Virginia , Luffman David , Rhodes Mia , Kurtz Madelyn
Published: June 2024

Rivers drive geomorphic change at Earth’s surface by transporting sediment from mountains to sedimentary basins. They are sensitive to changes in water and sediment flux driven by tectonism, climatic perturbation and or volcanism. We characterized changes in fluvial landscapes during a major Cenozoic cooling event, the Eocene-Oligocene Transition (EOT) at 33.9 Ma. The EOT is characterized by a long term ~4-5°C decrease in global mean annual temperature, punctuated by short, intense climatic fluctuations. In the Great Plains region of central North America, the temperature decreased by ~7°C and mean annual precipitation declined by ~50% across the EOT. Preceding the EOT, renewed Cordilleran uplift near northeastern Nevada began at ~39 Ma and extensive volcanism in the Great Basin region occurred at ~36 Ma. We reconstruct characteristics of rivers and floodplains through the Late Eocene-Early Oligocene deposits of White River Group (WRG), exposed at Toadstool Geologic Park in northwestern Nebraska, U.S.A., and evaluate how river landscapes responded to these events. We identified five stages of change in the paleo-rivers and -floodplain strata of the White River Group: (1) Following the Laramide uplift, the rivers of the Late Eocene Chamberlain Pass Formation adjusted from steep gradients (~10-3) to gentler ones (~10-4), and transitioned from shallow, mobile channels to deeper, stable channels and floodplains. (1) The transition from the Chamberlain Pass Formation to the Late Eocene Chadron Formation saw a shift from a relatively coarse-grained fluvial system with mobile channels to an extremely fine-grained, aggradational, floodplain-dominated system influenced by high volcanogenic sediment loads. (3) The transition from the Late Eocene Chadron Formation to the Early Oligocene Orella Member of the Brule Formation is associated with the onset of the Eocene-Oligocene Transition (EOT) and is marked by coarse floodplains and ephemeral river deposits that display evidence of significant, likely seasonality-driven, discharge variability. (4) Early Oligocene strata (33.9 - 31.6 Ma) also show compelling evidence of recurrent episodes of sustained channel incision and fill that we connect to climate fluctuations associated with the early phase of relatively rapid EOT cooling. (5) Early Oligocene strata deposited from 33.4 to 31.6 Ma show no significant erosional surfaces and continue to reflect discharge variability, high volcanogenic sediment loads, and a relatively stable climate system after the end of the initial phase of rapid cooling.
The Role of Media in Influencing FC Barcelona Supporters
Authors: FARRAS M. AZMI
Published: June 2024

This paper explores the significant role media plays in shaping the behaviors, attitudes, and emotions of FC Barcelona supporters. Media, in its various forms, acts as a powerful tool in creating and maintaining a passionate fan base. The study delves into how traditional media and digital platforms contribute to the collective identity of FC Barcelona supporters, the impact of media narratives on fan perceptions, and the ways media enhances fan engagement and loyalty. Through a combination of qualitative and quantitative methods, this research aims to provide insights into the symbiotic relationship between media and football fandom.
Consumerism and Materialism Culture: Its Impact on Society and the Environment
Authors: Amrilah Duta
Published: June 2024

The phenomenon of consumerism and materialism culture has become a global trend that has a significant impact on society and the environment. This study aims to identify and analyze the impact of consumerism and materialism culture on society and the environment by using quantitative methods and library research. The research findings show that consumerism and materialism culture have significant negative impacts on society and the environment. In the social aspect, consumerism and materialism culture encourage hedonistic behavior, individualism, and unhealthy social competition. On the economic aspect, consumerism and a culture of materialism lead to personal and family debt, inflation, and economic crises. On the environmental aspect, consumerism and a culture of materialism lead to the depletion of natural resources, environmental pollution, and climate change. Consumerism and a culture of materialism have serious consequences for society and the environment. Efforts to promote responsible and sustainable consumption are needed to minimize their negative impacts.
Exploring Automatic Approach-Avoidance Tendencies: The Impact of Self-Relevant Social Feedback on Behavior
Authors: Kim Jinhee , Lee Meeseung , Chae Jihwan , Lim Gahyun , Kim Minyoung , Kim Hackjin
Published: June 2024

Previous studies have reported automatic approach-avoidance tendencies toward various stimuli such as words, face expressions, and images in the appetitive or aversive valence domain. This work investigates whether self-relevant evaluative feedback affects theses behavioral tendencies using a touchscreen-based approach and avoidance task, in which participants responded to two-colored fish icons either by swiping down or by push away. Evaluative feedback on participants' personality traits provided by the fish served as a task-irrelevant feature. A pronounced valence-congruence effect for positive feedback relative to negative feedback was observed. Interestingly, higher social desirability ratings of social feedback were associated with faster RTs for approach trials and slower RTs for avoidance trials. Personality traits were associated with approach tendencies and avoidance tendencies: higher BFNE scores predicted a slower approach for both positive and negative feedback compared to neutral feedback, whereas higher depression symptoms predicted faster avoidance of negative feedback. This study demonstrates automatic approach and avoidance tendencies toward self-relevant social feedback, indicating a behavioral predisposition that may be automatically triggered by social feedback. Additionally, this study lays the groundwork for the development of touchscreen-based approach-avoidance tasks for measuring individual differences in the sensitivity of social feedback information and the strength of behavioral predispositions.
Practice What You Preach? Exploring Parental Attitudes Toward, Modeling of, and Teaching About Lying
Authors: Lucieer Ines Constance , Roza Emma Charlotte Anne , Lucassen Nicole , Bocanegra Bruno , Clegg Jennifer , Warnell Katherine Rice , Weeland Joyce , Kok Rianne
Published: June 2024

Objective. A growing number of studies demonstrate that most parents lie to their children. Paradoxically, most parents also disapprove of lying to their children and teach them that lying is unacceptable, suggesting discrepancies between parental attitudes toward lying to children, their modeling of lying behavior, and their teaching about lying. This study presents the first empirical investigation into the alignment of parental attitudes, modeling, and teaching across three lie types: other-oriented, self-oriented, and instrumental lies. Design. Cross-sectional data were gathered from Dutch parents (N = 312, 79.8% mothers) via an online questionnaire. Correlational analyses were performed to explore the between-parent associations between attitudes toward, modeling of, and teaching about other-oriented, self-oriented and instrumental lies. Moreover, Latent Profile Analyses were performed to explore how attitudes, modeling, and teaching cluster together within individual parents. Results. The findings regarding between-parent associations suggest a general alignment between parental attitudes, modeling, and teaching, that varied in strength across different types of lies. However, within-parent analyses reveal that most parents were discrepant in their attitudes, modeling, and teaching. The prevalences and patterns of alignment, as well as discrepancies differed per type of lie. Conclusion. Many individual parents show discrepancies between their attitudes, modeling, and teaching. These discrepancies indicate that these parents do not practice what they believe or preach. This study not only sheds new light on the existing literature of parental alignment and discrepancies between their attitudes toward, modeling of, and their teaching about lying but also proposes novel hypotheses regarding potential mechanisms underlying parental discrepancies, such as parental stress, hierarchical dynamics, and societal norms.