bluuebunny/crossref_metadata_2025 huggingface dataset:
Aktivitas Antibakteri Ekstrak Etanol Daun Binahong Terhadap Staphylococcus aureus dan Propionibacterium acnes Penyebab Jerawat
Authors: Sasebohe Vibe Yunita , Prakasita Vinsa Cantya , Aditiyarini Dwi
Published: January 2023

Jerawat merupakan salah satu masalah pada kulit yang disebabkan oleh peningkatan produksi sebum, pengelupasan keratinosit, inflamasi serta pertumbuhan bakteri. Masalah ini sering dialami oleh banyak orang dan berdampak pada penurunan kepercayaan diri, menimbulkan rasa tidak nyaman, serta berkurangnya interaksi sosial. Staphylococcus aureus dan Propionibacterium acnes merupakan bakteri yang sering menginfeksi jerawat. Pengobatan dengan antibiotik yang tidak tepat dapat menimbulkan resistensi bakteri penyebab jerawat. Tanaman binahong dimanfaatkan oleh masyarakat untuk pengobatan tradisional. Kandungan senyawa fitokimia yang ada pada daun binahong diduga memiliki aktivitas antibakteri. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri dari ekstrak daun binahong terhadap Staphylococcus aureus dan Propionibacterium acnes penyebab jerawat. Daun binahong diekstrak dengan metode maserasi menggunakan etanol 70% dan dilakukan screening fitokimia. Uji antibakteri dilakukan dengan metode diffuse disc, kemudian dilanjutkan dengan metode micro-dilution untuk mengetahui Minimum Inhibitory Concentration (MIC) dan metode swab untuk mengetahui Minimum Bactericidal Concentration (MBC) terhadap bakteri target. Ekstrak etanol daun binahong memiliki kandungan flavonoid, alkaloid, saponin, dan tannin yang memiliki daya hambat terbaik pada konsentrasi 80% terhadap Staphylococcus aureus dan Propionibacterium acnes dengan masing-masing diameter zona hambat 14,66±0,57 mm (kuat) dan 11,66±0,57 mm (kuat). Nilai MIC terhadapStaphylococcus aureus sebesar 20% dan terhadap Propionibacterium acnes sebesar 5%. Nilai MBC terhadapStaphylococcus aureus sebesar 60% dan terhadap Propionibacterium acnes sebesar 5%
Developing Soft Skills through Digital Didactic Games at the Stage of General Education
Authors: Petlina Elena , Zvereva Larisa , Korchak Konstantin
Published: January 2023

Digitalization has changed the methods of developing new skills and abilities in schoolchildren. New approaches have to be designed to plan training sessions and implant the basic ideas about professional competence. Modern supra-professional skills also require novel methods. This research featured digital didactic games as a means of developing supra-professional competencies. The authors reviewed available publications on professional and supra-professional competencies and their development methods. They described the semantic structure of the soft skills formation model through the use of digital didactic games. Didactic games are effective in developing soft skills and have a great digital potential, e.g., certain parts of a didactic game can be digitally personalized. The article describes didactic games, their requirements, and specific soft skills that are considered mandatory as part of supra-professional skills. The research relied on the principles of consistency and the holistic approach to academic processes, as well as on the connection between logic, history, theory, and practice. The article can help educators to develop new didactic games for various disciplines.
Constitutional and Legal Values of Liberalism and Conservative Political Tradition: Dialectics of Conflicting Paradigms
Authors: Kim Yurii
Published: January 2023

The first decade of the XXI century saw an explosive growth of conservatism in Russian government and society. This process resulted in the scientific focus on the domestic and foreign theoretical heritage in this philosophical and political-legal aspect. The question remains whether the Russian conservatism is directive or only recommendatory. At this moment, it is the current political vocabulary that is conservative, not the actual activities. The gap between the proclaimed tasks and the liberal model of the current Constitution is growing wider. The dead-end nature of the Russian political system had been obvious long before its adoption in 1993. The present study substantiates the urgent need for the development of the scientific heritage accumulated by the domestic conservative tradition and its transformation into a program with a clear roadmap. The article focuses on the theoretical provisions, generalizations, and conclusions made by N. Ya. Danilevsky, which may be applied to the current state of Russian statehood and its prospects. The Russian state studies need a new scientific paradigm, primarily in the field of constitutional law.
Lay Participation: Schöffen Courts and Jury Trials
Authors: Biryukova Olga
Published: January 2023

Lay participation is an indicator of a democratic society. This article analyzes some traditional forms of lay participation in criminal proceedings, in particular, the Schöffen courts in Germany and jury trials in the UK, e.g., the main competencies of people's judges, staffing rules, etc. The author highlighted some general and special disadvantages, as well as those associated with the application of these forms in Russian criminal trials. The diachronic analysis of courts with people's assessors and jury courts revealed a number of differences and similarities. In Russia, Schöffen courts took place during the reign of Catherine the Great, as well as in the Soviet period; jurors participated in criminal trials in the second half of the XIX century and still do. The article also describes the current domestic legislation on lay participation in judicial proceedings.
Constitutional Reform in the Second Half of the 1930s: Completing the Soviet Nation-Building Processes
Authors: Gavrilov Stanislav , Velichko Aleksey , Vinnichenko Oleg
Published: January 2023

The article deals with historical and legal problems related to the state and law development of the USSR during the period of socialist modernization. The authors believe that the constitutional reforms of 1936–1939 were part of the Soviet legitimization at the final stage of socialist state-building. The legitimization strategy consisted in the declaration of a new nature of statehood based not on the narrow social stratum of factory proletariat, but on the society as a whole. The essential changes in the ideological paradigm included the rejection of the former Marxist idea that the state naturally fades away after the socialist construction is completed. The goals of the legitimization strategy included a stable state power, a coherent political course, a new ideology to oppress the opposition sentiments, and a better international image. These goals resulted in significant changes to the constitutional legislation, including the norms that enshrined some principles of democratic statehood. The need to develop the Constitution of the USSR in 1936 arose from the intention of the authorities to prevent social tension, to ensure that the law corresponded to the real socio-economic and political situation, and to optimize the structure of public power. The country could not abandon the congress model of state administration because of the resistance of regional elites, which could have been overcome by a more liberal electoral legislation. The analysis provided a new interpretation of the Great Terror policy. The legal democratization after the constitutional reform, the repressions of 1937–1938, and the bureaucratization of public administration were links in the same chain that revealed a liberal-bureaucratic trend in the state and legal development of the USSR in the 1930s.
Jensens ekphrasis in “The King’s Fall” as “interference”
Authors:   St. Petersburg State University, Lomagina Anastasia ,   Herzen State Pedagogical University of Russia
Published: January 2023

The article analyzes an example of ekphrasis from the novel “The King’s Fall” (1901) by Danish Nobel prize-winner Johannes V. Jensen as a space of interaction between visualization strategy and rhythmic organization of prose. The idea of “interference” as a principle of mutual influence of waves in Physics is dear to the writer at this early stage of his career and is present in the title of the poem in prose from 1901. His turn-of-the-century poems and prose often combine high and low, emptiness and fullness, and different kinds of media. As a historical novel describing the epoch of the 16th century, “The King’s Fall” borrows the pictorial features and structural principles of Baroque painting as well as the essential ideas of the epoch’s memento mori, reflected in the paintings of H. Holbein, P. Bruegel the elder and still-lifes of Flemish and Dutch masters from the Vanitas series. The ekphrasis under consideration is presented as a piece of memory unfolding before the eyes of an observer, as a painting from the epoch with its frame, light, perspective, horizon line, colours and viewer. Furthermore, thanks to rhythmicity, repeated syntactic, lexical groups and alliteration, the focus shifts to the creative act, betraying the presence of the creator and the narrator.
The potential of modern foreign sociology in the study of social suffering
Authors:   Altai State University, Popov Evgeniy A.
Published: January 2023

The article focuses on the conceptualization of the sociology of suffering. The foreign experience of the development of the sociology of suffering in theoretical and applied aspects is considered. Modern researchers in understanding social suffering focus on psychological or anthropological interpretations, but the potential of the relevant branch of sociological knowledge is increasing over time. Meanwhile, the scientific problem is connected with two circumstances, which are reflected in this article. First, we are talking about the need to concretize the role of sociology in the study of the phenomenon of social suffering. Often the prevailing philosophical and psychological interpretations of suffering do not allow this to be done. In them, social suffering appears as an existential state of individuals or a phenomenon of their emotional and sensual tension and experience. However, in sociology, suffering needs to be objectified and considering it only as an existence cannot be productive for relevant sociological research. Secondly, modern studies of social suffering are mainly interdisciplinary in nature and do not reflect the special role of sociology in them. The article shows that the foreign sociology of suffering draws attention to a fairly wide range of phenomena associated with the emergence of social suffering. Here we mean the civilizational aspect, value-normative, sociocultural and others. The role of qualitative and quantitative methods in the study of social suffering is also assessed. Qualitative methods (for example, event analysis, intentional analysis, and others) allow us to present social suffering through the prism of object-subject relations. In this regard, some modern studies of social suffering are analyzed, which allow us to talk about the active development of the relevant branch of sociological knowledge.
Protests of health care workers during the health care reform: Representation of discourse in digital media
Authors:   Sociological Institute of the Russian Academy of Sciences — Branch of the Federal Center of Theoretical and Applied Sociology of the Russian Academy of Sciences, Boyarkina Saniya I.
Published: January 2023

The article dwells on study of adaptation mechanisms implemented by medical workers in online and offline spaces in a situation of ongoing changes in institutional healthcare environment. An analysis of the discourse, elements of its rhetoric is carried out. It allows to suggest the reasons for persistence of the protest moods in professional community over the past decades. At the first stage of the study content analysis of the medical Internet portal was carried out. There were analyzed the materials of the “Profession” section for the period from 2011 to 2015. The target audience of it is medical workers. News reports about protest actions carried out by the labor collectives of Russian healthcare facilities during the period of the healthcare system reform (N=51) were studied. At the second stage, from the comments (N=2104) of the members of the forum (direct speech), a base of linguistic elements (N=35 183) was formed; a frequency analysis of the text corpus was carried out; elements of the protest discourse rhetoric were identified. In the course of the analysis, it was revealed that the protest activity of the professional community is supported by status deprivation, ignoring the needs and interests of medical workers by representatives of the dominant groups — officials and employers — and their legal insecurity. In the offline space these problems become a motive for integrating the community to overcome bureaucratic barriers and carry out collective action — holding protests. In the on-line space, in the discussion of the objective situation, the adaptive mechanism of emotionally focused coping is implemented; emotions of resentment type find expression. In general, the transformation of the institutional foundations of health care system is perceived by physicians as traumatic, threatening the stability of the professional community’s social well-being and the socio-cultural foundations of medical practice.
Between sound and noise: Features of urban soundscapes formation
Authors: Vasileva Daria A. , Lermontov Daniil A. ,   HSE University
Published: January 2023

Soundscapes of a city as a cultural-symbolic space mediating our perception of sounds and noises are dynamic, changeable and heterogeneous. The way of everyday life, cultural experience, audio-visual texts are consumed outline different trajectories of interaction with sonic environment and make the border between sound and noise quite fluid. This article presents ethnographic data, important for understanding the process of formation of urban soundscapes. The research of St Petersburg soundscapes was conducted by the authors in 2016–2021 demon strated the possibilities of using such methods as “sound diary” and “sound walk”. The article is based on the analysis of 380 hours of observations made by 38 citizens, data from 19 interviewswalks with people living in 15 different microdistricts are presented. As the results the article represents the specificity of sounds and noises categorization, as well as the role of sonic experience in the formation of patterns of interaction between St Petersburg citizens and the urban environment. The research provides tools for analysing the social and cultural superstructure of the perception of urban sounds and noises, which is possible be of interest to sociologists, urbanists, urban anthropologists, ecologists, and researchers of local communities.
Towards a risk ranking for improved management of discharges of fats, oils, and greases (FOG) from food outlets
Authors: Collin Thomas , Cunningham Rachel , MacAdam Jitka , Villa Raffaella , Jefferson Bruce , Jeffrey Paul
Published: January 2023

The understanding of fats, oils, and greases (FOG) pathways in commercial kitchens is relatively poor. In this contribution, we extend our understanding of how FOG is perceived and managed by those working within food service establishments (FSEs). A questionnaire (n = 107) exposes awareness of and experiences with FOG and characterises two important behaviours: kitchen appliance cleaning regimes and waste management practices. Findings demonstrate that awareness of issues caused by FOG in sewer networks is independent of job role or position and that a majority of respondents (74%) are acquainted with the impacts of poor FOG management. Application of a risk ranking approach revealed a low risk of emissions from waste frying oils and exposed behaviours which can serve to reduce FOG emission potential including pre-rinsing of plates and cleaning of fryers and extraction hoods. Critically, 69% of FSEs had no means of managing their FOG emissions. We conclude that sampled FSEs were generally unaware of the relative contribution of FOG sources, thereby limiting their ability to respond to the behavioural and technological options available for minimising its impact. The risk ranking developed in this paper could be used to suggest efforts to reduce and mitigate FOG emissions from FSEs.
Estimation and mapping of water quality parameters using satellite images: a case study of Two Rivers Dam, Kenya
Authors: Omondi Alice Nureen , Ouma Yashon , Kosgei Job Rotich , Kongo Victor , Kemboi Ednah Jelagat , Njoroge Simon Mburu , Mecha Achisa Cleophas , Kipkorir Emmanuel Chessum
Published: January 2023

The continuous water quality monitoring (WQM) of watersheds and the existing water supplies is a crucial step in realizing sustainable water development and management. However, the conventional approaches are time-consuming, labor intensive, and do not give spatial–temporal variations of the water quality indices. The advancements in remote sensing techniques have enabled WQM over larger temporal and spatial scales. This study used satellite images and an empirical multivariate regression model (EMRM) to estimate chlorophyll-a (Chl-a), total suspended solids (TSS), and turbidity. Furthermore, ordinary Kriging was applied to generate spatial maps showing the distribution of water quality parameters (WQPs). For all the samples, turbidity was estimated with an R2 and Pearson correlation coefficient (r) of 0.763 and 0.818, respectively while TSS estimation gave respective R2 and r values of 0.809 and 0.721. Chl-a was estimated with accuracies of R2 and r of 0.803 and 0.731, respectively. Based on the results, this study concluded that WQPs provide a spatial–temporal view of the water quality in time and space that can be retrieved from satellite data products with reasonable accuracy.
When Serum C-Peptide Measurement Drives Adequate Diabetes Mellitus
Diagnosis and Therapy: A Case Report
Authors: Piazzolla Giuseppina , Lisco Giuseppe , Volpe Sara , Triggiani Domenico , Triggiani Vincenzo
Published: January 2023

Background:

Therapeutic targets in type 2 diabetes mellitus (T2D) are oriented towards nephron- and cardio-protection and the prescription of antihyperglycemic agents with proven renal and cardiovascular benefits are increasing over time. Failure to promptly diagnose insulinopenic diabetes may adversely affect the adequacy of treatment and have harmful consequences, including severe hyperglycemia and diabetic ketoacidosis.

Case Presentation:

Herein we present the case of a 57-year-old woman referred to our clinic due to
poor glycemic control (HbA1c 80 mmol/mol, therapeutic target <53 mmol/mol), class III obesity
(BMI 41 kg/m2; normal value <25 kg/m2), and high cardiovascular risk misdiagnosed with T2D
several years before. C-peptide measurement (0.3 ng/dL; reference range 1.1 – 4.4 ng/mL) confirmed
the diagnosis of an insulinopenic form of diabetes, and the islet autoimmunity was consequently
measured (GADA 2,000 UA/mL, reference range <5 UA/mL; IA2 17.1 UA/mL, reference range
<7.5 UA/mL) and defined the diagnosis of an autoimmune form of diabetes.

Discussion:

Deprescribing insulin therapy in T2D patients in favor of other antihyperglycemic medications has become a growing therapeutic opportunity to provide adequate glucose control, promote weight loss, improve insulin sensitivity, and ameliorate cardiovascular and renal outcomes. However, due to immediate problems, a blunted insulin reserve poses a significant restriction on the prescription of non-insulin agents (e.g., diabetic ketoacidosis due to gliflozins). According to our experience, the routine testing of insulin reserve provides detailed information on diabetes pathophysiology with positive implications for the appropriateness of pharmacological prescriptions.

Conclusion:

As part of our routine evaluation of diabetic patients, C-peptide measurement is a valuable and inexpensive tool to reclassify diabetes types and provide more appropriate disease management.
Metabolites Study of Experimental Plant Derived Alkaloids: A Review
Authors: Manna Kuntal , Somraj Singh Waikhom , Goswami Sanchari , Ashif  Ikbal Abu Md , Rajkhowa Amlanjyoti , Debnath Bikash
Published: January 2023

Alkaloids are waste products of plant metabolic processes, containing at least one nitrogen
atom in the heterocyclic ring. They serve a wide variety of physiological functions in humans and animals.
Metabolism plays a central role in regulating the toxicity of various phytochemicals. Available literature
of biological sources and metabolism study of pyrrolidine, pyrrolizidine, pyridine, quinoline, isoquinoline,
phenanthrene, phenethylamine, indole, terpenoid, and aporphine groups of experimental plantsderived
alkaloids were collected from the Google Scholar, PubMed/Medline, Science Direct, Scopus,
Wiley Online Library, and Web of Science search engines. The literature reveals that hepatic microsomal
enzymes such as monooxygenase and putative NADPH-FMN-reductase, carboxyl esterase, CYP2B6,
CYP3A4, and CYP2D6 are primarily involved in the metabolism of alkaloids. This review may encourage
natural product researchers to further research and develop new plant-derived alkaloidal drugs.
Analyses of moral values of student activists’ protest demonstrations in Sunan Kalijaga State Islamic University Yogyakarta
Authors: Maksudin Maksudin
Published: January 2023

Protest demonstrations are legal according to Law of the Republic of Indonesia Number 9 of 1998 about Freedom to Express Opinions in Public. This study aims to comprehensively analyze the moral values of the student activists’ protest demonstrations in Sunan Kalijaga State Islamic University Yogyakarta regarding the causes, demands, and processions. The study was done using the principles of field research which employed the qualitative approach in the form of the case study method. The researcher holistically looked into the activities and processes of the students’ protest demonstrations. Data were elicited by several techniques, namely in-depth interviews, questionnaires, observations, and documentation. Data were analyzed by using the NVivo 12 Plus software. Findings show that student activists’ protest demonstrations generally focused on the single tuition fee policy and other campus and government policies which do not favor students and citizens. Students’ protest demonstrations in Sunan Kalijaga State Islamic University Yogyakarta carried along 28 good moral values and 15 bad moral values which means that students’ demonstrations had more good moral values than the bad ones. It can be concluded that it is not appropriate to judge students’ protest demonstrations to carry along only either good or bad moral values.
Misconception of reading literacy and its impacts on literacy acculturation in school
Authors: Fauzan Fauzan , Eriyanti Ribut Wahyu , Asih Ria Arista
Published: January 2023

Literacy competencies are important for students to keep abreast of the pace in the 4.0 industrial age. Misunderstanding of the concept of literacy may result in the incorrect application of literacy acculturation. This study is aimed at 1) describing teachers’ misconceptions of reading literacy and 2) describing the implementation of students’ reading literacy acculturation at school. Data were collected from teachers’ and students’ statements and activities during the literacy acculturation activities in the participating schools from 19 regencies in East Java, Indonesia. Additional data were in the forms of documents and field notes obtained from observation, interviews, questionnaires, and documentary studies. The results show that: 1) the concept of literacy is understood as literal and mechanistic reading, and 2) schools tend to apply formal literacy activities by asking students to read texts 15 minutes before classes begin. Several problems are found in most research sites in which there is no follow-up on the given free reading assignments, teachers and school principals neither become literacy models, the availability of fiction and non-fiction books is limited, and students are not highly motivated to follow the reading literacy program. This study implies the urgent need to improve all school stakeholders understanding of the literacy concept and provide better activities for the implementation of the reading literacy acculturation program in schools.
An analysis of the learning implementation of physical education in junior high schools
Authors: Khairuddin Khairuddin , Masrun Masrun , Bakhtiar Syahrial , Syahruddin Syahruddin
Published: January 2023

This study aims to analyze the learning implementation of Physical Education in public junior high schools in the city of Padang, Indonesia, paying particular attention to the learning activities of students and teachers, the models and approaches employed, and the degree of physical fitness of the students.. This research is survey research involving students (n=100) and Physical Education teachers (n=10) from 5 schools in the urban city, and 5 schools in the suburbs. Questionnaires and Indonesian physical fitness tests for the 13-15 year age group were used to collect the research data. Descriptive statistics were used for the analysis. The findings indicated that teachers' and students' movement-related learning activities in physical education were evaluated as low. Physical education teachers have used sports techniques with the command method rather than modifying sports games as a model for learning.. Only 20.00% of them are student-centered, with 80.00% of them being more teacher-centered. Then, with a classification of less and very less, it was discovered that students' levels of physical fitness were below average, or 53.00%... In conclusion, to achieve the objectives of physical education, physical education teachers should significantly prepare for learning as well as become proficient in a wide range of efficient learning techniques (cognitive, affective, and psychomotor). Future research is required to validate the findings of this study, including the conception of a sports game-modified learning model in physical education.
كاریگه‌رى میدیاى نوێ له‌سه‌ر ره‌فتارى سیاسی تاك به‌شدارى سیاسی به‌نموونه‌ (توێژینه‌وه‌یه‌كى شیكارى و مه‌یدانییه‌)ه‌
Authors: Abdullah Kanaan Hamagharib , Mohammad Radhwan Abu Bakr
Published: January 2023

گۆڕانکاریە خێراکانی تەکنۆلۆژیای زانیاری بە تایبەتی پلاتفۆرمەکانی سۆشیاڵ میدیا زەمینەیەکی نوێیان بۆ بەشداری سیاسی وه‌ك پێوه‌رى ره‌فتارى سیاسی ره‌خساند. بەرپرسانی سیاسی له‌لایه‌ك و جەماوەر له‌لایه‌كى دیكه‌ ئه‌مرۆ ئاره‌زومه‌ندانه‌ به‌شێوه‌یه‌كى به‌رچاو ئامرازه‌كانى په‌یوه‌ندى به‌كار ده‌هێنن و كاریگه‌رى له‌سه‌ر یه‌كدى داده‌نێن، چونکە سۆشیاڵ میدیا ئامڕازێکی دوو سەرەیە و بە شێوەیەکی ئاسان لە ڕێگەی مۆبایلى زیره‌كه‌وه‌ (سمارتفۆن) لە چرکەیەکدا هەر دوولا دەتوانن بکەونە گفتوگۆیەکی کاراوە، هه‌رئه‌مه‌شه‌ وا ده‌كات جەماوەر دەتوانێت ڕۆژانە ره‌فتارى سیاسی بنوێنێت و فیدباک و ڕەخنە و پێشنیارو ڕاسپاردە بداتە بەرپرسان و ئەوانیش دەتوانن سیاسەتەکانیان لە ڕێگەی بۆچونەکانی جەماوەرەوە دابڕێژن، كه‌واته‌ میدیاى نوێ خوڵقێنه‌رى دوو جۆر ره‌فتارى سیاسییه‌ له‌نێوان (فه‌رمان ره‌واو فه‌رمانپێكراو) كه‌ئه‌م كاریگه‌رییه‌ به‌راورد به‌‌میدیاى ته‌قلیدى ده‌گمه‌ن بوو، ئەم توێژینەوەیەش بە مەبەستی شیکاری بۆ ئاستى كاریگه‌رى میدیاى نوێ له‌سه‌ر ره‌فتارى سیاسی تاك چه‌قبه‌ندى ده‌كات كه‌ سه‌ره‌راى لایه‌نى تیۆرى و هه‌وڵ دراوه‌ به‌ چاوپێكه‌وتن و فۆرمى راپرسى به‌ده‌ره‌نجامێكى وردى زانستى بگات.
Making Sense of Theories, Models, and Frameworks in Digital Health Behavior Change Design: Qualitative Descriptive Study
Authors: Voorheis Paula , Bhuiya Aunima R , Kuluski Kerry , Pham Quynh , Petch Jeremy
Published: January 2023

Background

Digital health interventions are increasingly being designed to support health behaviors. Although digital health interventions informed by behavioral science theories, models, and frameworks (TMFs) are more likely to be effective than those designed without them, design teams often struggle to use these evidence-informed tools. Until now, little work has been done to clarify the ways in which behavioral science TMFs can add value to digital health design.

Objective

The aim of this study was to better understand how digital health design leaders select and use TMFs in design practice. The questions that were addressed included how do design leaders perceive the value of TMFs in digital health design, what considerations do design leaders make when selecting and applying TMFs, and what do design leaders think is needed in the future to advance the utility of TMFs in digital health design?

Methods

This study used a qualitative description design to understand the experiences and perspectives of digital health design leaders. The participants were identified through purposive and snowball sampling. Semistructured interviews were conducted via Zoom software. Interviews were audio-recorded and transcribed using Otter.ai software. Furthermore, 3 researchers coded a sample of interview transcripts and confirmed the coding strategy. One researcher completed the qualitative analysis using a codebook thematic analysis approach.

Results

Design leaders had mixed opinions on the value of behavioral science TMFs in digital health design. Leaders suggested that TMFs added the most value when viewed as a starting point rather than the final destination for evidence-informed design. Specifically, these tools added value when they acted as a gateway drug to behavioral science, supported health behavior conceptualization, were balanced with expert knowledge and user-centered design principles, were complementary to existing design methods, and supported both individual- and systems-level thinking. Design leaders also felt that there was a considerable nuance in selecting the most value-adding TMFs. Considerations should be made regarding their source, appropriateness, complexity, accessibility, adaptability, evidence base, purpose, influence, audience, fit with team expertise, fit with team culture, and fit with external pressures. Design leaders suggested multiple opportunities to advance the use of TMFs. These included improving TMF reporting, design, and accessibility, as well as improving design teams' capacity to use TMFs appropriately in practice.

Conclusions

When designing a digital health behavior change intervention, using TMFs can help design teams to systematically integrate behavioral insights. The future of digital health behavior change design demands an easier way for designers to integrate evidence-based TMFs into practice.
News Media Coverage of the Problem of Purchasing Fake Prescription Medicines on the Internet: Thematic Analysis
Authors: Almomani Hamzeh , Patel Nilesh , Donyai Parastou
Published: January 2023

Background

More people are turning to internet pharmacies to purchase their prescription medicines. This kind of purchase is associated with serious risks, including the risk of buying fake medicines, which are widely available on the internet. This underresearched issue has been highlighted by many newspaper articles in the past few years. Newspapers can play an important role in shaping public perceptions of the risks associated with purchasing prescription medicines on the internet. Thus, it is important to understand how the news media present this issue.

Objective

This study aimed to explore newspaper coverage of the problem of purchasing fake prescription medicines on the internet.

Methods

Newspaper articles were retrieved from the ProQuest electronic database using search terms related to the topic of buying fake prescription medicines on the internet. The search was limited to articles published between April 2019 and March 2022 to retrieve relevant articles in this fast-developing field. Articles were included if they were published in English and focused on prescription medicines. Thematic analysis was employed to analyze the articles, and the Theory of Planned Behavior framework was used as a conceptual lens to develop the coding of themes.

Results

A total of 106 articles were included and analyzed using thematic analysis. We identified 4 superordinate themes that represent newspaper coverage of the topic of buying prescription medicines on the internet. These themes are (1) the risks of purchasing medicines on the internet (eg, health risks and product quality concerns, financial risks, lack of accountability, risk of purchasing stolen medicines), (2) benefits that entice consumers to make the purchase (eg, convenience and quick purchase, lower cost, privacy of the purchase), (3) social influencing factors of the purchase (influencers, health care providers), and (4) facilitators of the purchase (eg, medicines shortages, pandemic disease such as COVID-19, social media, search engines, accessibility, low risk perception).

Conclusions

This theory-based study explored the news media coverage of the problem of fake prescription medicines being purchased on the internet by highlighting the complexity of personal beliefs and the range of external circumstances that could influence people to make these purchases. Further research is needed in this area to identify the factors that lead people to buy prescription medicines on the internet. Identifying these factors could enable the development of interventions to dissuade people from purchasing medicines from unsafe sources on the internet, thus protecting consumers from unsafe or illegal medicines.
ENTHESIS AS AN ORGAN AND ITS PATHOLOGIES
Authors:   Ural State Medical University, Zhilyakov Alexander A. , Kokorina Margarita L. ,   Ural State Medical University, Zerchaninova Elena I. ,   Ural State Medical University
Published: January 2023

Excessive overstrain of the tendon apparatus occurs in athletes and people performing heavy physical work. Untimely treatment, or its complete absence, can lead to the development of severe diseases of the musculoskeletal system. The effectiveness of therapy is influenced by the doctor’s understanding of modern ideas about the pathogenesis of tendinopathy. Purpose. To study and summarize the available literature data on the epidemiology and pathogenesis of tendinopathy. Materials and methods: we conducted a literary review of scientific papers over the past 30 years using the resources of the PubMed and eLibrary search engines. Results. According to the data found, the process of degenerative tendon injury consists of three stages: reactive tendinopathy, tendon injury and degenerative tendinopathy. The speed of the degenerative process is affected by the age and duration of excessive load. Thus, stage 3 tendinopathy can be considered as a breakdown of the adaptive inflammatory-reparative reaction, which developed as a result of inadequate treatment of partial damage to tendon tissues due to a single excessive mechanical impact or regularly recurring microtrauma. Conclusion. The article presents various theories of the structural formation of tendinopathy, which can help in studying the pathomorphogenesis of degenerative changes in the tendon-ligamentous apparatus during its injury or chronic overstrain.
ANTIOXIDANT ACTIVITY OF NUTRIENT MEDIA DURING CULTIVATION OF PSEUDOMONAS AERUGINOSA AND ESCHERICHIA COLI
Authors:   Bashkir State Medical University, Mochalov Konstantin S. , Nozimov Jakhongir Ikromjon Ugli ,   Bashkir State Medical University, Galimova Saida Sh. ,   Bashkir State Medical University, Muratov Emil M. ,   Moscow scientific research oncological Institute named after P. A. Herzen, Galimov Kamil Sh. ,   First Moscow State Medical University named after I.M. Sechenov, Kufterina Alexandra D. ,   Bashkir State Medical University, Bodrova Elizaveta S. ,   First Moscow State Medical University named after I.M. Sechenov, Galimova Elmira F. ,   Bashkir State Medical University
Published: January 2023

Bacteria of different species, due to the peculiarities of their metabolism, have different abilities to counteract the formation of free radicals and oxidative stress. An indicator reflecting the development of oxidative processes is the antioxidant activity of nutrient media during the cultivation of bacteria. The aim of the study. Comparative evaluation of the antioxidant activity of nutrient media samples during the cultivation of P. aeruginosa and E. coli. Materials and methods. The antioxidant activity of nutrient media was assessed by recording iron-induced chemiluminescence. Spontaneous antioxidant activity of nutrient media samples, as well as their parameters under conditions of oxidative stress, were evaluated. Results. It is shown that the nutrient medium in which P. aeruginosa was cultivated has a greater antioxidant activity than the medium with E. coli. Conclusions. The results obtained may indicate a better ability of P. aeruginosa to counteract the formation of free radical agents compared to E. coli.
Pre-Revolutionary Activities of Astrakhan Diocesan Committee, 1915 – Early 1917: Analyzing Materials from the State Archive of Astrakhan Oblast
Authors:   Kalmyk Scientific Center of the RAS, Kurapov Andrey
Published: January 2023

Introduction. The article introduces into scientific circulation a set of documents contained in Collection 597 — ‘Astrakhan Diocesan Committee of the Missionary Orthodox Society’ — of the State Archive of Astrakhan Oblast and some publications of the Astrakhan Diocesan Gazette to examine missionary activities of the Committee in Kalmyk Steppe during the pre-revolutionary years (1915 – early 1917). Materials and methods. The work employs comparative and historical / descriptive methods of historical research to focus on a set of archival documents from 1915 – early 1917, the latter to include reports on missionary endeavors of the Committee, activity reports of missionary institutions and camps, accounts of pastoral work, reports and analytical notes submitted by missionaries throughout the period under review. Results. The last phase of activity of Astrakhan Diocesan Committee is characterized on the basis of a set of documents from the State Archive of Astrakhan Oblast introduced into scientific circulation. Conclusions. The investigated materials make it possible to consider the main directions and results of missionary activities undertaken by the Russian Orthodox Church in Kalmyk Steppe, determine key centers of missionary life and their conditions, missionary personnel, and their efforts to participate in communities of the faithful during the pre-revolutionary period.
Microcréditos y autonomía económica de las mujeres en situación de pobreza: un análisis bibliométrico
Authors: Velarde Flores Cecilia Lorena , Velázquez Contreras Lorenia
Published: January 2023

Objetivo: proponer un marco de revisión de la literatura sobre los programas de microcrédito para las mujeres y su efecto en la reducción de la pobreza, a partir de un análisis bibliométrico que muestre las relaciones y las tendencias de los conceptos microcrédito y autonomía económica de las mujeres. Metodología: descriptiva con diseño documental en la que se usan las herramientas del software VOSviewer sobre una base de datos de 434 documentos resultante de la búsqueda en la plataforma Scopus. Limitaciones: solo se consideró la base de datos Scopus para el periodo 1992-2021. Resultados: la mayoría de las investigaciones se enfocan en Asia (India y Bangladesh) y se publican principalmente en Estados Unidos. Mediante el análisis de coautorías, se identificaron los principales autores, instituciones y países. Del análisis de coocurrencias de palabras, se desprenden tres clústeres: microcrédito, desarrollo humano y desarrollo económico. Valor: la construcción de una base bibliográfica para estudios sobre microcréditos y autonomía económica. Conclusiones: los estudios más recientes sobre la eficacia del microcrédito para las mujeres muestran la necesidad de incluir, además de las económicas, otras dimensiones al evaluar estas políticas de apoyo, tales como las relaciones de poder, las asimetrías de género y el contexto sociocultural.
Comparison of estrus response and subsequent fertility following estrus synchronization with six protocols in Ossimi ewes during the early summer season
Authors: Almadaly Essam A. , Sahwan Ferial , Wael B El Domany , Radwan Ahmed , Shukry Mustafa , Farrag Foad
Published: January 2023

This study investigates the effect of estrus synchronization on the reproductive performance of Ossimi ewes during the early summer season to prove that they are cyclic throughout the year in subtropical climates. In June, 280 ewes were assigned to seven (n = 40) groups and received one of the following: 1) short-term progesterone (ST) P4 treated ewes received 20 mg P4 day after day for 6 days and 500 international unit (IU) equine chorionic gonadotropin (eCG) on day 6; 2) long-term P4 (LT) P4 treated ewes received 20 mg P4 day after day for 12 days and 500 IU eCG on day 12; 3) double prostaglandin (PG) F2α 7days apart and 500 IU eCG on day 7 (PGF2α-7d); 4) double PGF2α 14 days apart and 500 IU eCG on day 14 (PGF2α-14d); 5) traditional ovulation synchronization (T-Ovsynch; gonadotropin-releasing hormone (GnRH)-0 day; PGF2α-5 day and GnRH-7 day); 6) non-traditional ovulation synchronization (NT-Ovsynch; GnRH-0 day; PGF2α-7 day and GnRH-9 day); 7) control ewes received no treatment. There were significant differences among groups for estrus rate, the onset of estrus, pregnancy, and lambing rates as well as prolificacy and gestation period. The highest (90 %) estrus rate was recorded in (LT) P4, PGF2α-14d, and NT-Ovsynch protocols while the lambing rate was the maximum (100 %) in PGF2α-14d. Although all treatments had a positive effect on ewe fertility; long-term protocols particularly PGF2α-14d; are recommended to improve Ossimi ewe fertility during the early summer season.
The Educational Effect of Storytelling-based Real-Life Problem-Solving Artificial Intelligence Convergence Education Program for Pre-service Informatics Teacher
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kim Ji-Yun , Jeon In-Seong , Kim Kwihoon
Published: January 2023

Objectives In this study, the storytelling-based real-life problem-solving artificial intelligence convergence education program was applied to pre-service Informatics teachers, and its educational effect was verified by focusing on confluence competency.
Methods The storytelling-based real-life problem-solving artificial intelligence convergence education program was implemented as a major subject of the Informatics teacher training course, and the effectiveness of the program was confirmed by comparing the students' creativity confluence competency before and after the experimental treatment.
Results As a result of the paired-sample t-test for the pre-post tests, a statistically significant improvement was confirmed both in creativity confluence competency and each sub-factor. In addition, when looking at each item, statistically significant improvements were confirmed before and after the experimental treatment in 56 of the 59 items.
Conclusions The storytelling-based real-life problem-solving artificial intelligence convergence education for pre-service Informatics teachers is meaningful in that research on artificial intelligence convergence education for pre-service or in-service Informatics teachers needs to be revised. However, Informatics teachers play a significant role in artificial intelligence convergence education in the school field, so understanding artificial intelligence convergence education should be the basis, and related studies must be conducted continuously.
Exploring the possibilities of picture book project as art centered project based learning(A-PBL)
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kang Joohee , Lee Jiyeon
Published: January 2023

Objectives In this study, Considering picture books as a synthesis of ‘art in life’, the value of picture books as art and the process of creating picture books as an art are applied to project-based learning to explore practical cases and suggest their possibilities.
Methods This action research analyzed based on the process of creating picture books as art, reflection reports, and feedback from the instructor.
Results Art centered project-based learning (A-PBL) was conducted with the research participants, and a picture book came out as a final creation through the process of project planning, project exploration, project production, and project presentation.
Conclusions The experience of project-based learning develops teamwork and reinforces cooperative learning, allowing learners to take the initiative in constructing the curriculum. The instructor also reconstructs the project by reflecting the context during execution. The learner not only strengthens the learning motivation but also learns an attitude of reflection.
Transbronchial lung cryobiopsy guided by virtual bronchoscopy navigation in a child with diffuse alveolar hemorrhage syndrome：a case report
Authors: yang haiming , MaimaitiailiTailaiti * , Ma Mina , Zhang Xiaoyan , Wang Feng
Published: January 2023

there are several advantages to the use of transbronchial lung
cryobiopsy (TBLC), including less trauma, fewer complications, large and
high-quality specimens, and lower cost. This procedure is mainly used
for the etiological diagnosis of diffuse parenchymal lung diseases
(DPLD) [2] and its most common complications, including bleeding and
pneumothorax. Virtual bronchoscopy navigation (VBN) can assist
bronchoscopists in pinpointing the target area in the lung and designing
an appropriate navigation pathway to accurately reach the target lesion
[3]. Thus, VBN improves the rate of diagnosis and reduces the risk
of bleeding and pneumothorax. In this report, which we believe to be the
first of its kind, we performed TBLC guided by VBN.
Historic disturbance events may overrule climatic factors as drivers of ruderal species distributions in the Scandinavian mountains
Authors: Wiegmans Dymphna , Larson Keith , Clavel Jan , Spreeuwers Jasmine , Pirée Amber , Nijs Ivan , Lembrechts Jonas
Published: January 2023

The contemporary interaction of climate and land use change drives
vegetation composition and species distribution shifts, making their
respective roles difficult to disentangle. In this study, we
investigated long-term ruderal plant species distributions along the
‘Rallarvägen’ trail in Abisko, subarctic Sweden – a trail established
for railroad construction in 1903 and paralleled by the E10 Highway
(since 1982). Using vegetation and climate data from 1903, 1913, 1983,
and 2021, we found that warm-adapted ruderal plant species were already
common along the Rallarvägen at its initial creation at the start of the
20th century. Interestingly, however, many of these native and
non-native ruderals with relatively high temperature affinity that were
present in 1903 and 1913, disappeared since then and did not return,
despite the substantial rise in temperature in the region over the last
decades. The historical disturbances also had long-lasting effects on
the current spatial distribution of the ruderal vegetation. Most
ruderals still reside close to the railroad tracks and are progressively
filtered out with increasing distance from anthropogenically disturbed
introductory points, such as train stations, where they peak in richness
– a process we coined Horizontal Directional Ecological Filtering, in
parallel to the established concept of Directional Ecological Filtering
along elevational gradients. We conclude that it is important to know
the disturbance history of a system to get a good understanding of the
long-term dynamics in the vegetation community, and thus its possible
future in a changing climate.