bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH PROSEDUR, FEE DAN PROFESIONALISME AUDIT TERHADAP KUALITAS AUDIT DENGAN REMOTE AUDIT SEBAGAI VARIABEL MODERASI STUDI EMPIRIS PADA KANTOR AKUNTAN PUBLIK DI JAKARTA SELATAN
Authors: Risdiana Dina , Asmanah Siti , Hakim Luqman
Published: June 2024

This study aims to determine Procedures, Audit Fees and Professionalism on Audit Quality with Remote Audit Moderating Variables (Study at Public Accounting Firm in South Jakarta). This research method is included in quantitative research with the type of primary data source and uses attribution theory and positive accounting theory. The population in this study were public accounting firms in the South Jakarta area and the samples in this study were partners, supervisors, managers and seniors who worked at public accounting firms in the South Jakarta area. The number of samples in this study were 92 respondents. Data analysis in this study used the SmartPLS (Partial Least Square) Version 4.0 data analysis method. Procedures have a significant effect on audit quality, audit fees have a significant effect on audit quality, and professionalism has a significant effect on audit quality. Meanwhile, remote audit has no significant effect on moderating the relationship between procedures and audit quality, remote audit is unable to moderate the relationship between audit fees and audit quality. In addition, remote audit is able to moderate the relationship between professionalism and audit quality.
PELESTARIAN KEARIFAN LOKAL MANUGAL DI DESA SUMBER GARUNGGUNG KECAMATAN DUSUN TENGAH KABUPATEN BARITO TIMUR
Authors: Wulandari  , Suryadi Achmad , Azahra Nur Shellae , Agustianti Wandry , Irawan Aldi , Arifin Samsul , Agustiani Reni , Elsandika Gabriela
Published: June 2024

Kegiatan pengabdian kepada masyarakat ini dilaksanakan di Desa Sumber Garunggung, Kecamatan Dusun Tengah, Kabupaten Barito Timur. Tim mengajak masyarakat untuk melaksanakan pertanian berkelanjutan dengan tetap menjunjung tinggi kearifan lokal melalui sistim bahuma atau berladang. Kegiatan bahuma yang dipilih yaitu manugal, menanam padi di lahan kering. Proses manugal dilakukan bertahap sesuai dengan adat istidat masyarakat setempat. Kegiatan ini bertujuan untuk melestarikan kembali budaya nenek moyang agar tidak hilang di kalangan generasi muda. Selain itu kegiatan manugal dapat memberikan dampak positif bagi masyarakat lokal dan global, seperti meningkatkan solidaritas, dan melestarikan budaya.
Supplementing a Non-probability Sample With a Probability Sample to Predict the Finite Population Mean
Authors: Xu Zihang , Nandram Balgobin
Published: May 2024

We show how to analyze a non-probability sample (nps) with limited information from a small probability sample (ps). The most practical case is when the nps has auxiliary variables and study variable but no survey weights and the ps has  known weights, auxiliary variables, but no study variable. Two samples are taken from the same population and the variables are common to both the nps and the ps. A large non-probability sample can reduce the cost but will give biased estimator with small variance, the small probability sample can provide supplemental information. Following this, we apply these weights to fit a mixture model, enhancing the robustness of the results and enabling the estimation of the finite population mean. Additionally, we present a method to enhance the efficiency of the Gibbs sampler.
The Physical Geography of Eastern Taiwan as a Baseline for Tourism and Earthquake Hazards
Authors: Reinbold Rebecca , Mitchell Martin
Published: May 2024

The eastern region of Taiwan is underpinned by a complex tectonic setting that forms the basis for numerous landforms, such as the Coast Range, Longitudinal Valley and Central Range, along with a rocky shoreline punctuated by a series of scenic beaches. In many ways, this tectonic setting resembles that of the west coast of North America. Taiwan’s climate ranges from tropical monsoon (Am) with periodic typhoons to temperate and even subalpine climates based on dramatic changes in altitude caused by the tectonic setting. This situation produces a host of different ecological zones based on vertical zonation. The physical setting, along with recent infrastructure improvements, forms a baseline for tourism. Moreover, comprehending the region’s structural geology is crucial for understanding the region’s risk of severe earthquakes, as exemplified by the recent 7.4 magnitude earthquake on April 2, 2024, near the east coast city of Hualien. Our methodology centers on a review of pertinent literature and field reconnaissance conducted in 2014, 2016, 2019, 2020 and 2024.
Growth Response of Cucumber in Different Solid Organic Waste Materials
Authors: Rubillos Blessy G. , Ponio Kazel Geian , Pendon Jear Claudette M. , Ondap Janis Krishna C.
Published: June 2024

The study aims to investigate the effect of various organic waste materials on the growth of cucumber plants. The study is motivated by the increasing need for sustainable agricultural practices and the potential use of organic waste as a source of nutrients for plant growth. The experiment will be conducted using a randomized complete block design with three treatments: food scraps, animal manure, yard waste. Cucumber seeds will be sown in pots filled with soil mixed with the respective organic waste material. The growth parameters such as plant height and length of leaves will be measured at regular intervals. It is hypothesized that cucumber plants grown in soil amended with organic waste materials will exhibit better growth compared to those with no fertilizer. This hypothesis is based on previous studies that have shown the positive impact of organic waste on plant growth due to its nutrient content. The results obtained from this research will contribute to our understanding of the potential use of different organic waste materials as a sustainable alternative to synthetic fertilizers in agriculture. It may also provide insights into effective methods for recycling and managing organic waste for agricultural purposes.
A Study on Fish Consumption Pattern among Pregnant Women in Kashmir Valley
Authors: Arif Fiba , Bhat Bilal Ahmad
Published: June 2024

Fish is one of the most important sources of animal protein, vitamins, minerals and fatty acids, essential for the maintenance of health and metabolism. Besides, fish is reckoned as an ideal diet for expectant and lactating women owing to its high nutritional value and health benefits. In this paper, in order to assess the fish consumption pattern among the pregnant women of Kashmir, the current study was carried out in Kashmir valley of J&K region during June 2023. We explained the purpose of study to the respondents and after taking their consent, we chose 200 respondents at random on the basis of consecutive sampling procedure during the study period using a well- designed validated questionnaire and via direct personal interviews. The data collected from our survey was analysed statistically and interpreted using appropriate statistical tools. The study revealed that majority of the respondents consumed fish occasionally during pregnancy. The major reason for inappreciable consumption was found to be the lack of awareness about the health benefits of fish during this phase. Moreover, consumption pattern of fish was related to the educational background of the respondents as comparatively higher percentage of respondents who consumed fish was found to be educated. However the consumption pattern was not significantly associated with the family status. Hence, the study elicits the need to effectively communicate the benefits of fish consumption in order to encourage proper nutrient intake among pregnant and lactating mothers and their children.
Assessment of Testosterone Levels, Kidney Function and Alkaline Phosphatase in Patients with Benign Prostatic Enlargement in Kirkuk City/Iraq
Authors: Ibrahim Dhafer Fayeq , Abdulrahman Sahib Jumaah , Salih Amjed Ạbbawe
Published: June 2024

The present study is designed to evaluate the concentration of Testosterone, Creatinine, Urea urea, and alkaline phosphatase levels in patients with benign prostatic hyperplasia. This study was conducted for the period from the beginning of October 2023 to the end of February 2024 at Kirkuk Hospital. General and specialized medical clinics in the city of Kirkuk. The study included (70) males with benign prostatic hyperplasia, ages (45-75) years, and average weight (82) kg. In addition to 20 samples of healthy people with the same rate of ages and weights of patients, study samples were distributed as follows: The first group: the control group and included (20) healthy males, and the second group: the patient group and distributed to three groups according to the age groups first category ( 45-55) years and included 25 patients, the second age group (56-65) years and included 20 patients, the third age group (66-75) years and included 25 patients. The results of the current study showed a significant increase (p ≤ 0.05) in the concentration of urea, creatinine and alkaline phosphatase enzyme in patients with benign prostatic hyperplasia compared to healthy people, and the current study showed a significant decrease (P ≤ 0.05) in testosterone concentration in patients with benign prostatic hyperplasia compared to healthy people. According to age groups, the results showed no significant differences (p ≤ 0.05) in the concentrations of urea, creatinine and alkaline phosphatase enzyme in patients with prostatic hyperplasia, and the results showed a significant decrease (p≤ 0.05) in the concentration of testosterone according to the age groups of patients with benign prostatic hyperplasia.
Reversible bilateral postauricular adult seborrheic dermatitis due to sodium valproate-valproic acid combination
Authors: Örüm Mehmet Hamdi , Örüm Dilek , Çevik Osman
Published: May 2024

The combination of sodium valproate-valproic acid, commonly used to treat epilepsy and bipolar disor-der, may result in cutaneous reactions. In this case report, we presented a bilateral postauricular sebor-rheic dermatitis associated with sodium valproate-valproic acid use. A sodium valproate-valproic acid combination was introduced to the therapy of a 68-year-old male patient who had been diagnosed with schizophrenia and was on clozapine in order to potentially avoid seizures associated to the medication. On the fifteenth day of drug addition, crusting appeared on the back skin of both ears of the patient. While the patient had a history of clozapine use, there was no history of sodium valproate use or similar cutaneous symptoms. The current condition was associated with the sodium valproate-valproic acid combination and the drug was discontinued. Following discontinuation of the medication, the crusting decreased and disappeared completely after two weeks. The patient's schizophrenia-related treatment was completed and he was discharged. No cutaneous reaction was observed again during follow-up. It should be noted that cutaneous reactions may be associated with the use of sodium valproate-valproic acid combination.
Estudo acerca das etapas do desenvolvimento econômico proposto por Walt Whitman Rostow: uma análise comparativa entre os municípios do estado do Espírito Santo à luz da teoria
Authors: Oliveira Ricardo Daher , Oliveira Leila Cristina da Silva
Published: June 2024

Este projeto tem como foco realizar um estudo comparativo entre os municípios do Estado do Espírito Santo à luz das ideias de Rostow, visto que, um dos propósitos da municipalização é o de desenvolvimento da região. Contudo verifica-se que ao longo da história, diversos municípios não obtêm êxito na promoção do desenvolvimento regional, o que acaba contribuindo para o êxodo rural face ao fato da geração de emprego ficar comprometida pela ineficiência do município em estimular o desenvolvimento da região. Visto assim, este trabalho faz uma revisão acerca dos entraves ao desenvolvimento descrito por W.W. Rostow para que, após, seja possível realizar uma correlação entre os municípios mais desenvolvidos com menos desenvolvidos de forma a verificar a presença dos fatores descritos pela teoria proposta por Rostow. Para tanto, elenca-se um conjunto de informações relacionadas aos dados econômicos dos municípios de forma a posicioná-los nas Etapas sugerias no Modelo Teórico de Rostow.
Otimizando ganhos no sistema de integração lavoura-pecuária-floresta: aplicação da otimização multiobjetivo
Authors: Costa Gilson de Souza , Ferko Geórgia Patrícia da Silva , Bitar Sandro Dimy Barbosa , Lopes Jalison
Published: June 2024

O sistema de Integração Lavoura-Pecuária-Floresta - ILPF é uma abordagem agrícola integrada que visa maximizar a eficiência produtiva e a sustentabilidade ambiental. O objetivo deste estudo foi aplicar ferramentas matemáticas, especialmente a otimização multiobjetivo, para identificar soluções que equilibram os aspectos econômicos, ambientais e sociais do sistema ILPF. Este estudo de caso investigou o equilíbrio na produção de um sistema de ILPF na Fazenda São Paulo, em Iracema-RR. Utilizando técnicas de otimização multiobjetivo, foram exploradas diferentes combinações de culturas agrícolas, criação de gado e plantio de árvores. Usando o solver do Excel, foi encontrado a melhor distribuição da área cultivada para otimizar a produção de grãos, árvores e criação de gado, levando em consideração a emissão e sequestro do metano. No caso, houve uma ferramenta testada para o apoio à tomada de decisão para produtores rurais em busca da sustentabilidade e eficiência nos sistemas ILPF, contribuindo assim para o desenvolvimento de práticas agrícolas mais sustentáveis e resilientes.
Soybean response to preplant application of auxin herbicides at different soil textures
Authors: Silva Diecson Ruy Orsolin da , Cuchi Marina Luiza , Novello Bruna Dal’Pizol , Basso Claudir José
Published: June 2024

Glyphosate-resistant or tolerant broadleaves are often controlled using auxin herbicides before soybean planting. However, a safe interval is essential prior soybean planting, depending on soil properties. In the literature, there is little information about auxin herbicides on the behavior of auxin herbicide at different soil texture. Two soil residual bioassays were conducted in a greenhouse to evaluate response to soybean to preplant applications of 2,4-D and dicamba at different soil textures. Herbicides were applied 28, 21, 14, 7, 3 and 0 days before soybean planting (DBP) and the soil texture consisted 15, 35 and 60 % clay. The residual activity was determined through the injury, plant height and dry weight of soybean at 28 DBP. Soil residues from 2,4-D was less deleterious to soybean than dicamba. The herbicides injury is reduced in clayey soil. Shorter intervals of herbicide application increased the injury and reduce height and dry weight of soybean. Soil texture not influence on height and dry weight from 2,4-D. Dicamba caused high injuries in medium soil compared to clayey and sandy soil, and clayey soil revealed cause lower effect on height and dry weight of soybean. The 2,4-D application in clayey soil reduces the interval to soybean planting, but soil texture not influence on initial soybean development. The 2,4-D application in clayey soil reduces soybean injury, but soil texture not influence on initial soybean development. Up to the 28-days interval, there are no indications of soil texture effect on the herbicide dissipation security for soybean planting.
Implementação do modelo Calgary e a sistematização da assistência de enfermagem ao paciente com esclerose lateral amiotrófica
Authors: Ferreira Amanda Maria dos Santos , Lima Marize Conceição Ventin , Santos Geórgia Maria Ricardo Félix dos , Barbosa Jéssica Andréia Pereira , Silva Rêneis Paulo Lima , Neves Leandro de Lima , Belmonte Bernardo do Rego , Santana Marllon Alex Nascimento
Published: June 2024

Introdução: A Esclerose Lateral Amiotrófica é uma doença neurodegenerativa que ocorre devido à degeneração progressiva de neurônios motores superiores e inferiores sem acometer a atividade intelectual e cognitiva. Nesse cenário, o papel da família é fundamental para a qualidade de vida do paciente. O Modelo Calgary de Avaliação Familiar (MCAF) visa destacar problemáticas que podem interferir na relação paciente-família e trazer soluções eficazes a fim de facilitar o convívio tanto com a equipe de saúde quanto entre paciente e família. Objetivo: Apresentar a abordagem da família de acordo com a avaliação da implantação do modelo de Calgary, diagnósticos de enfermagem para o paciente, segundo a Sistematização da Assistência de Enfermagem (SAE), e para a família, segundo o MCAF. Metodologia: Trata-se de um estudo de caso, descritivo, com abordagem qualitativa, do tipo estudo de caso único, que é uma investigação sobre uma única situação, na qual participaram um paciente e sua filha, no município de Olinda/PE. Foi realizada a técnica de entrevista, a partir da qual buscou um aprofundamento dos dados. Resultados: A ferramenta utilizada do MCAF através da entrevista e a implantação da SAE possibilitaram a construção do genograma e do ecomapa, propondo estratégias de resolutividade e compreensão das relações familiares durante a discussão do artigo. Conclusão: Pode ser observada a eficácia da utilização dos instrumentos do MCAF e da SAE, os quais possibilitaram a integração da equipe de saúde e da família para a resolutividade dos desafios enfrentados.
Análise do escore Lace na readmissão hospitalar precoce em pacientes de clínica médica
Authors: Bernal Suelen Cristina Zandonadi , Souza Vanessa Duarte de , Silva Roberta Graciele Saran da , Mercado Paula Andrea Gatica , Radovanovick Cremide Aparecida Trindade
Published: June 2024

A readmissão hospitalar precoce é um fenômeno desafiador que afeta os sistemas de saúde globalmente, impondo consideráveis ônus financeiros às instituições de saúde e resultando em consequências adversas para os pacientes. Objetivo: Analisar o uso do escore LACE como ferramenta preditora de readmissão hospitalar precoce e verificar fatores associados. Método: Coorte retrospectiva de pacientes admitidos em clínica médica, entre 2020 e 2022. Para análise estatística foi usado o teste qui-quadrado, correlação Pearson, além da análise bivariada para verificar os fatores associados. Resultado: Dos 1.742 pacientes, a maioria era do sexo masculino, raça branca, idade média de 61 anos, com ensino fundamental. Destes 238 pacientes foram readmitidos em até 30 dias, com taxa de readmissão de 13,66%. O escore LACE indicou alto risco de readmissão para 63,26% dos pacientes. Associações significativas foram encontradas entre readmissão e escolaridade (p = 0,039) e categorias do escore LACE (p = 0,018).Conclusão: Destaca-se a importância do escore LACE e fatores sociodemográficos na identificação de pacientes com maior probabilidade de readmissão, sugerindo estratégias de cuidados pós-alta direcionadas para melhorar resultados clínicos e reduzir taxas de readmissão.
Symbiotic relationships and biological effects of inoculation with plant growth-promoting bacteria in forage species
Authors: Snak Aline , Santos Marise Fonseca dos , Schmidt Matheus , Vieira Adriá Braun , Gonçalves Júnior Affonso Celso , Vendruscolo Eliane Cristina Gruszka
Published: June 2024

Brazil has the largest commercial cattle herd and it is the largest commercial exporter in the world, an important characteristic of Brazilian cattle raising is having most of its herd raised to pasture. Due to the high cost of chemical fertilizers, the interest for bacterial inoculants has grown. The objective of this work was to identify forage specimens with better association with different bacterial strains in order to promote plant growth. Experiments, with a completely randomized design, where three forage species were evaluated: white oat (Avena sativa L.), brachiaria ruziziensis (Urochloa ruziziensis) and Millet (Pennisetum glaucum), inoculated with four bacterial strains: Azospirillum brasilense, Herbaspirilum seropedicae, Ensifer adherens and Leclercia adecarboxylata. Seed asepsis was performed with acidified hypochlorite and afterward the seeds were transferred to agar / water medium and incubated for 48 h at 32 ° C in the dark. The pre-germinated seeds were placed in test tubes containing 25 mL of MS medium and inoculated with 106 CFU.mL-1 of each of the strains, except for E. adherens which was inoculated with 104 CFU.mL-1. After 21 days of in vitro culture, the following factors were evaluated: length, fresh and dry weight of shoot and root biomass, gross protein and total nitrogen quantification, root morphology by staining with 1% methylene blue, stoma morphology and microbial counting (epiphytic and endophytic). Data were submitted to ANOVA and compared by the Tukey test (p >5%). The different forage species presented different behavior in relation to the association with the bacterial strains. Oats and Brachiaria were considered as more responsive to the bacterial association than Millet because they presented a larger increment in the size of central / lateral roots and root area. Although Oat presented significant results for BP and TN, Brachiaria had a larger epi and endophytic population, indicating that it was preferential for bacteria.
THE ROLE OF THE CONSTITUTIONAL JUDGE IN SAFEGUARDING PUBLIC RIGHTS AND FREEDOMS
Authors: Nawal Daim
Published: May 2024

Objectives: This study aims to shed light on the role played by the constitutional judge in protecting the rights and freedoms of individuals, highlighting the aspects of oversight over the constitutionality of laws. It begins by examining comparative constitutional systems, followed by an exploration of the Algerian experience to understand the various aspects of this oversight, particularly after the adoption of the constitutional amendment in 2020, which established the Constitutional Court instead of the Constitutional Council that Algeria had known since 1989.
 
Methodology: The study adopts a range of scientific research methods, starting with the analytical approach, which involves analyzing constitutional and legal texts governing the work of the Constitutional Court. Additionally, a comparative approach is employed, comparing the mechanisms of constitutional oversight in different countries, as well as comparing the new powers of the constitutional judge in the newly established Constitutional Court according to the 2020 constitutional amendment with the provisions related to the work of the court, as it was previously for the Constitutional Council.
 
Results: We concluded that oversight over the constitutionality of laws, as a guarantee for public freedoms, varies between political and judicial oversight, and it has been adopted in most comparative constitutional systems, including the Algerian system, which introduced the Constitutional Court as a constitutional institution that protects individual freedoms by ensuring the respect of laws and regulations for the constitution and avoiding any violation of it through issuing decisions regarding their conformity with the constitution. Despite the recent establishment of this constitutional institution, it has proven to be effective and efficient in addressing any legal provision that may violate the constitution and infringe upon the rights and freedoms of individuals.
 
Conclusion: Constitutional oversight is considered one of the most important guarantees for safeguarding the rights and public freedoms of individuals. Given the supreme position of the constitution, legal provisions should not contradict its broad meaning. Algeria, starting from the issuance of the 2016 constitution, recognized the concept of unconstitutionality, allowing any litigant before ordinary or administrative judicial bodies to claim that a legislative or regulatory judgment applied to the dispute violates their rights and freedoms guaranteed by the constitution. After the constitutional amendment of 2020, the Constitutional Court became an independent institution entrusted with ensuring respect for the constitution with expanded powers. Within the framework of the powers of the constitutional judge, in addition to what has been mentioned, it is worth noting that the Constitutional Court, as a guarantee for rights and freedoms, issues an opinion when the President of the Republic submits a constitutional amendment, provided that it does not affect the rights and freedoms of individuals.
UMA ANÁLISE DE QUESTÕES DE MATEMÁTICA COMERCIAL E FINANCEIRA NO ENEM
Authors: Lobato Júnior José Maria dos Santos , Corrêa Tonival de Sarges , Souza Tatiane Cardoso de , Costa José Francisco da Silva
Published: June 2024

Este trabalho teve como objetivo analisar o impacto que as questões de Matemática Comercial e Financeira causam na pontuação do estudante ao realizar o Exame Nacional do Ensino Médio. Dessa forma, nosso foco principal foi fazer um demonstrativo da quantidade de questões presentes no ENEM desde o ano de 2009 a 2022. Para isso, apresentamos um breve histórico do ENEM e conceitos, formulações e exemplos da Matemática Comercial e Financeira. Além disso, discorremos sobre a importância dessa área na vida cotidiana do indivíduo e, por fim, mostramos que até 1/4 das questões do ENEM é sobre esse objeto de estudo. A busca dessas informações foi por meio de uma pesquisa bibliográfica, em sites. Ao final, consideramos que um acerto de todas as questões de Matemática Comercial e Financeira traz uma boa pontuação na prova do estudante, além de que, ao assimilar esse conhecimento o ajudará a tomar decisões nas transações de natureza comercial e financeira.
EFICÁCIA E SEGURANÇA DE FÁRMACOS VIA ORAL PARA O MANEJO DO DIABETES MELLITUS TIPO 2
Authors: Marinho Konnery Kazelly , Ferrari Kelly Rosa Ferreira
Published: June 2024

O Diabetes Mellitus (DM), uma doença crônica influenciada por fatores genéticos e ambientais. O número de adultos que vivem com diabetes aumentou significativamente desde 1980, chegando a 422 milhões em 2020, com projeção de chegar a 693 milhões até 2045. A classificação do DM inclui o tipo 1 (DM1), causado pela destruição autoimune das células beta; o tipo 2 (DM2), devido à perda progressiva da síndrome de insulina e resistência a esse hormônio; o diabetes gestacional (DMG); e tipos específicos por outras causas. O DM2 é uma condição complexa influenciada por vários fatores de risco, como genética, idade, obesidade, sedentarismo, hipertensão, dislipidemia, tabagismo, entre outros. Intervenções no estilo de vida podem prevenir ou retardar a progressão do DM2. O papel da insulina no desenvolvimento do DM2 é ambíguo. Inicialmente, a insulina atua de forma benéfica, compensando a resistência à insulina. Porém, a hiperinsulinemia prolongada pode levar a defeitos na sinalização da insulina e do IGF-1, contribuindo para a disfunção e morte das células beta. Diversas opções farmacológicas, como Metformina, Tiazolidinedionas, Inibidores da alfa-glicosidase, Agonistas do receptor de GLP-1 e Inibidores do SGLT2, demonstraram eficácia na prevenção ou retardo do desenvolvimento do DM2, complementando as intervenções no estilo de vida. Um estudo com liraglutida 3mg demonstrou que esse medicamento levou a maior perda de peso e melhorou o controle glicêmico em pacientes com DM2 tratados com insulina, sem aumento do risco de hipoglicemia. Outro estudo com semaglutida oral mostrou que ela foi superior ao placebo na redução da hemoglobina A1c e peso corporal em pacientes com DM2 e insuficiência renal moderada, com um perfil de segurança consistente com a classe de agonistas do receptor GLP-1. A empagliflozina também apresentou redução clinicamente relevante na hemoglobina A1c em comparação ao placebo em pacientes jovens com DM2, embora tenha sorte mais relatos de hipoglicemia no grupo ativo. A dapagliflozina não apresentou efeito significativo no estágio inicial na análise de intenção de tratar, mas houve diferença significativa na análise de sensibilidade por protocolo, com perfil de segurança aceitável. Finalmente, a terapia com insulina glargina mais agentes antidiabéticos orais mostrou não ser inferior, porém mais segura (menor risco de hipoglicemia) do que a insulina asparte 30 mais metformina em pacientes chineses com DM2. Portanto, diversas opções farmacológicas demonstraram eficácia e segurança no tratamento do DM2, complementando as intervenções no estilo de vida.
Heat stress amelioration by astaxanthin supplementation and Nrf2 transcribed downregulation of HSP70 and MnSOD in Karan Fries (Holstein Friesian ×Tharparkar) heifers
Authors: KUMAR SUNIL , SINGH S V
Published: May 2024

Karan Fries (Holstein Friesian × Tharparkar) heifers are sensitive to heat stress due to exotic inheritance. Therefore their productive performances are affected adversely under tropical climatic conditions. Hence, the present study was conducted on Karan Fries (10-12 months) heifers by dividing into two group i.e. control (fed as per ICAR, 2013) and treatment group (additionally supplemented with astaxanthin @ 0.25 mg/kgBW/day/animal). Environmental parameters (dry and wet bulb temperature, and relative humidity) were recorded throughout the study and temperature humidity index (THI) was calculated. THI was used to assess the levels of summer stress. Blood samples were collected at fortnightly interval from both the groups of heifers for estimation of oxidative stress markers i.e. antioxidants enzyme (SOD, GPx and catalase). RNA was isolated from collected blood samples for Nrf2, HSP70 and MnSOD gene expression at monthly interval. Plasma catalase, SOD and GPx levels were lower in astaxanthin supplemented group of Karan Fries heifers than control group. The expression of HSP70 and MnSOD genes was down-regulated and Nrf2 was up-regulated in treatment compared to control group. The THI had a positive correlation with oxidative stress markers i.e. antioxidants enzyme (SOD, GPx & Catalase) as well as expression pattern of HSP70, and MnSOD genes. Based on the results of the present study, it can be concluded that astaxanthin (potent antioxidant) supplementation was effective in lowering the stress levels in treatment group by down-regulating the genes related to heat stress. Therefore, astaxanthin can be an effective supplement for ameliorating the adverse effect of heat stress, mainly in heat sensitive livestock species.
Seasonal trends in emission of odorous gases from growing-finishing swine houses
Authors: KUMARI PRIYANKA , CHOI HONG-LIM
Published: May 2024

The air quality in swine houses has caught attention of scientists and general public. The swine waste generates various odorous gases, which affects the health of farm workers and local residents. In this study, we investigated the composition and concentrations of three major groups (i.e. acidic, sulfuric and phenolic) of odorous gases in growing and fattening swine houses during winter and summer, and studied their relationship with aerial parameters (i.e. temperature and relative humidity). Among 10 different odorous gases measured, acetic acid was the most abundant odorous gas across both seasons. Except iso-valeric acid, dimethyl sulfide and dimethyl disulfide, the concentrations of other odorous gases varied significantly between winter and summer. The concentrations of these odorous gases were significantly higher in winter, except for p-cresol, which was significantly higher in summer. The aerial temperature showed significant positive correlations with concentrations of most of the acidic and sulfuric groups odorous gases, whereas, relative humidity was negatively correlated with concentrations of relatively fewer members of acidic and sulfuric groups odorous gases. The relationships studied here could be useful in regulating the emission of odorous gases from growing and fattening swine houses.
ANALISIS RESPON MAHASISWA TERHADAP KOMEDI PINGGIR JURANG
Authors: Maulida Nasywa Gassani , Mubarok Rifa Hilman , Sadina Talitha Diva
Published: May 2024

: Penelitian ini bertujuan untuk mengetahui respon mahasiswa UPI terhadap konten komedi pinggir jurang yang mengarah pada isu-isu intoleransi. Artikel ini menggunakan metode penelitian kuantitatif. Pengumpulan data menggunakan angket yang disebarkan secara online melalui google form. Angket atau kuesioner berisi pertanyaan dengan beberapa pilihan jawaban. Selanjutnya hasil angket akan dianalisis secara deskriptif kuantitatif. Pada masa kini konten komedi yang mengandung intoleransi itu sedang tren di media sosial. Dari paparan di atas dapat disimpulkan bahwa mahasiswa terkadang menonton konten komedi dan menemukan konten komedi yang mengandung intoleransi. Ketika dihadapkan dengan konten seperti itu mayoritas mahasiswa melihatnya secara sekilas, itu berarti mahasiswa masih kurang peduli terhadap hal tersebut sehingga mereka mengabaikannya. Kebanyakan mahasiswa berpikir komedi dapat membantu orang-orang untuk memahami isu-isu intoleransi dan dapat membantu menguatkan toleransi, tetapi tergantung konteksnya juga dikarenakan ada beberapa konten komedi yang malah menyebabkan perpecahan.
Estrés académico y su relación con la autoestima en estudiantes de enfermería
Authors: Arias Chiluisa Anderson Daniel , Guadalupe Núñez Sara Verónica
Published: May 2024

Introducción: El estrés académico es un fenómeno prevalente en estudiantes universitarios, especialmente en carreras de alta exigencia como enfermería. La autoestima puede actuar como un factor protector frente al estrés y favorecer el desempeño académico. Objetivo: Relacionar el nivel de estrés académico con la autoestima en estudiantes de enfermería. Métodos: Estudio cuantitativo, observacional-transversal y de alcance correlacional. Se recogió información de manera censal a estudiantes de enfermería de séptimo semestre de la Universidad Técnica de Ambato, mediante el Inventario SISCO para evaluar el estrés académico y la Escala de Autoestima de Rosenberg para medir la autoestima. El análisis de datos se realizó con Microsoft Excel y SPSS versión 29. Resultados: La mayoría de los estudiantes (89,5%) presentaron un nivel de estrés profundo y un 40,8% mostraron un nivel de autoestima elevada. Se encontró una correlación significativa entre el estrés académico y la autoestima (0,000 p< 0,05). Conclusión: La mayoría de los participantes presentaron un nivel de estrés profundo, y un porcentaje considerable presentaron autoestima elevada. Además, se encontró una correlación significativa entre el estrés académico y la autoestima, lo que permitió aceptar la hipótesis alterna del investigador, es decir, el estrés académico tiene una correlación significativa con la autoestima en los estudiantes de enfermería de la Universidad Técnica de Ambato.
“EL GIRO Y EL AMARRE”: VISIONES DICOTÓMICAS DE LA EDUCACIÓN AFROPACÍFICA
Authors: Celorio-Angulo Wayner
Published: June 2024

El presente escrito pretende identificar aquellos discursos imbricados en el sistema escolar de las comunidades afrodiaspóricas que habitan el litoral Pacífico (en adelante afropacífico), representados en una serie de tensiones que se dan entre los imaginarios del proyecto nacional y la concepción de la educación propia planteada por dichos grupos humanos. El contraste de estas dos visiones pedagógicas (normativa y praxis) generan una serie de rupturas, puesto que la ideología del proyecto educativo nacional es represivo y homogeneizador, en tanto, la visión de los grupos afrodiaspóricos es liberadora y emancipatoria. El interés del autor está centrado en la comprensión del pensamiento afropacífico que subyace a la noción africana de acercarse y reproducir el conocimiento, procurando nuevos estadios de la condición obliterante de ‘atraso’ e ‘inferioridad’ impuestos por la modernidad-capitalista que imposibilita la diversidad étnica en los contextos mencionados..
LOS SIGNOS DE PUNTUACIÓN. UNA PROPUESTA DIDÁCTICA PARA SU ENSEÑANZA
Authors: Ospina-Ugalde Soraya
Published: June 2024

El aprendizaje de la lengua escrita supone un proceso largo y concatenado en el que es fundamental el dominio pleno de los signos de puntuación. La expresión escrita solo dispone de estos signos como recurso para representar la riqueza de matices que pueden estar presentes en el lenguaje hablado. Este artículo propone abordar la enseñanza de estas marcas gráficas como mecanismo clave de la organización y la jerarquización de las ideas a tono con el nuevo enfoque que le da a este aspecto la Real Academia Española de la Lengua en su libro de ortografía del año 2010. Para aprender a puntuar con propiedad, deben realizarse actividades a lo largo de toda la educación formal, con el objeto de desarrollar en los estudiantes el discernimiento en el uso de estos signos, dependiendo del tipo de discurso empleado, de lo que quieran expresar y de su estilo personal, entre otros factores.
Introduction
Authors: Shackel Paul A.
Published: May 2024

Anthracite coal was first discovered in the 1760s; however, it was not until the 1820s that the anthracite mining industry developed. By the 1830s, it began to be employed extensively for warming houses and a bit later for cooking. The East Coast industries replaced water power with steam power, creating a greater demand for anthracite. The increased extraction of coal fed the growing iron industry east of the Alleghenies, and as a result, iron became cheaper and more accessible to East Coast industries. The mid-nineteenth-century mass extraction of anthracite coal transformed a region and a nation and created a complicated story about the rise of unchecked capitalism, the racialization of the newest immigrants, the destruction of the environment, and the compromise of communities’ long-term health.
Net Zero in the Balance: A Guide to Transformative Industry Thinking
Authors: Urwin Roger
Published: June 2024

Net zero requires transformational changes and significant investment. This guide aids industry leaders in implementing net-zero investing. It offers practical guidance that stresses the importance of mindset shifts and highlights strategies for success.
Digital Marketing Trends and Innovations in Indonesia: A Qualitative Exploration of Emerging Practices
Authors: Hafidh Abdul Ahmad Hafidh Nurmansyah , Rahayu Agus , Hendrayati Heny
Published: June 2024

This qualitative research explores the evolving landscape of digital marketing trends and innovations in Indonesia. Against the backdrop of rapid technological advancements and a growing digital consumer base, this study aims to shed light on the current state of digital marketing practices in the Indonesian context. To achieve this, an in-depth qualitative approach was employed, involving interviews and content analysis of leading industry professionals and digital marketing campaigns. The findings reveal a dynamic environment characterized by the adoption of cutting-edge technologies such as artificial intelligence, influencer marketing, and personalized content strategies. Additionally, the study identifies the increasing significance of social responsibility and ethical considerations in digital marketing campaigns, reflecting a growing awareness among businesses to align with societal values. This research not only contributes to the existing body of knowledge on digital marketing trends but also provides valuable insights for businesses and marketers looking to navigate the Indonesian market's unique challenges and opportunities in the digital era.
Fundamentos de la Imagenología Médica
Authors: Quintero Santiago Jiménez , Martinez Aguilar Fernando Antonio , Rey Mora Maylin Roxana , Lozano Brun Óscar Iván , Ballesteros Trillos Juan Pablo , Uribe Chavez María Fernanda
Published: May 2024

El libro "Fundamentos de la Imagenología Médica" es una obra integral que se erige como un recurso esencial para estudiantes, residentes y profesionales de la medicina que buscan una comprensión profunda y actualizada de las técnicas y aplicaciones de la imagenología en el diagnóstico y tratamiento de enfermedades. Este texto aborda de manera exhaustiva los principios físicos y biológicos que sustentan las diversas modalidades de imagenología, así como su aplicación clínica y relevancia en la práctica médica contemporánea.
Antioxidant potential and xanthine oxidase inhibition of flavonol glycosides from Phyllanthus emblica L. leaves
Authors: Husnunnisa Husnunnisa , Hartati Rika , Mauludin Rachmat , Insanu Muhamad
Published: June 2024

Context: Hyperuricemia is the cause of gout in the inflammatory joint condition. The xanthine oxidase enzyme is a therapeutic target for gout treatment because it plays a role in the generation of uric acid. Allopurinol is used to treat gout. It prevents the xanthine oxidase enzyme from producing as much uric acid. When selecting a medication, one must consider the various adverse effects of allopurinol. Phyllanthus emblica plants are among the medicinal plants that can be used as an alternative treatment for gout. Aims: To evaluate isolated compounds from the Phyllanthus emblica as antihyperuricemia candidates. Methods: The isolated compounds were characterized using High-Performance Liquid Chromatography Analysis and Thin Layer Chromatography-Densitometry. The 2,2-diphenyl-1-picrylhydrazyl (DPPH) and cupric ion (CUPRAC) antioxidant capacity procedures were used to develop the antioxidant activity index. The ability to inhibit xanthine oxidase was determined using a spectrophotometer. Results: Compound 1 was indicated as rutin having antioxidant capacity with an antioxidant activity index (AAI) DPPH value of 7.89 ± 0.03 and AAI CUPRAC value of 15.83 ± 0.04 stronger than compound 2 (quercitrin) with an AAI DPPH value of 3.72 ± 0.01 and AAI CUPRAC 3.24 ± 0.03. The IC50 for quercitrin's inhibition of xanthine oxidase is 23.85 ± 2.04, which was higher than rutin’s IC50 value of 32.77 ± 4.49 µg/mL. Conclusions: Flavonol glycosides present in the ethanol extract of Phyllanthus emblica leaves gave potent xanthine oxidase inhibitory activity stronger than the extract. Quercitrin gave stronger xanthine oxidase inhibitory activity, but this compound has weaker antioxidant capacity compared to rutin.
Exploiting Biotechnological Tools to Boost Disease Resistance and Crop Productivity in Horticulture
Authors: Pal Sumit , Yadav Sudheer Kumar , Kumar Ashutosh , Bhadani Megha , Singh Pushpendra
Published: May 2024

Horticulture is a vital sector of agriculture that contributes significantly to global food security, nutrition, and economic development. However, the productivity and sustainability of horticultural crops are increasingly threatened by various biotic and abiotic stresses, including plant diseases, pests, climate change, and resource limitations. Conventional breeding approaches have made substantial progress in developing disease-resistant and high-yielding cultivars, but they are often time-consuming and limited by the available genetic diversity within the crop species. Recent advancements in biotechnology offer powerful tools to accelerate the breeding process and introduce novel traits into horticultural crops. This articleprovides an overview of the current status and future prospects of exploiting biotechnological tools to boost disease resistance and crop productivity in horticulture. It covers the application of marker-assisted selection, genetic engineering, genome editing, and other emerging technologies in major horticultural crops such as fruits, vegetables, and ornamentals. The articlealso discusses the challenges and opportunities associated with the deployment of these technologies, including regulatory issues, public acceptance, and the need for multidisciplinary collaboration. By harnessing the potential of biotechnology, we can develop more resilient and productive horticultural crops that contribute to food security, environmental sustainability, and socio-economic development.
La academia vista como campamento. Del rigor disciplinario al abuso de poder.
Authors: Angel Baquero Sergio , Ruíz Omara , Aguiló Alenmichel , Castellanos Dimas , Gallego José Raúl , Rodríguez Catalina , Herrera Maria Camila
Published: May 2024

El grupo de trabajo del Observatorio de Libertad Académica publica su trigésimo noveno informe titulado “La academia vista como campamento. Del rigor disciplinario al abuso de poder”, correspondiente al mes de marzo de 2024. Esta entrega se enfoca en el registro de dos casos donde la aplicación del reglamento docente responde al autoritarismo que permea todos los ámbitos de la sociedad cubana, imponiendo un esquema de ordenamiento cuasi militar que define un modelo pedagógico inobjetable.
Objectives of Administration and State Support of the Agro-Industrial Complex in the Far Eastern Federal District in the Context of Ensuring Food Security in Russia
Authors: Kharitonov N. M. , Komleva V. V. , Salikhov Sh. M.
Published: June 2024

The article depicts an urgent problem of ensuring food security of Russia – development of agro-industrial complex in Far Eastern Federal District. An analysis of current condition of agro-industrial complex and measures of its support is conducted. The position on insufficiency of general and special measures to support the agro-industrial complex in the Far Eastern Federal District is expressed. Specific solutions to identified problems are proposed. The article features the positions of correspondent ministries of the Russian Federation, deputies of the State Duma, the opinions of scientists and experts, unique materials for further research and scientific and practical analysis of problems in administering the Far Eastern Federal District regions. The publication was prepared based on the materials of the round table “On adopted measures of special legal regulation of the agro-industrial complex development in the Far Eastern Federal District”, held by the Committee for the Development of the Far East and the Arctic on February 22, 2024.
Diversidad y uso de especies cultivables en unidades productivas agropecuarias campesinas
Authors: Villarreal Chiriboga Brayan Alexis , Ortiz Tirado Paul Santiago , Valverde Obando Adrián Alexander , Cajas Naranjo Mariana Del Rocío , Pomboza Tamaquiza Pedro Pablo
Published: May 2024

La importancia de la biodiversidad en poblaciones rurales es de gran interés por su enorme contribución en la provisión de alimentos. El objetivo de esta investigación fue caracterizar la biodiversidad y uso de especies cultivables presentes en Unidades Productivas Agropecuarias (UPA) campesinas, en la parroquia Santa Rosa, Provincia de Tungurahua. Se aplicaron 185 encuestas a 10 organizaciones campesinas de la zona (al 100% de sus miembros). Las actividades agropecuarias se desarrollan en lotes de menos de 1 Ha, con más del 50% de mano de obra familiar, se evidencia que el fraccionamiento de los lotes continúa. El índice de Shannon y Weaver (H´= 5.3) muestra que la riqueza y diversidad presentes en estas unidades es alta. En total se caracterizaron 49 especies cultivadas en estos sectores, el promedio de especies por UPA fue de 21.4 de ellos se encontraron 5.8 nativas y 15.7 introducidas. Existe un predominio de especies introducidas sobre las nativas, ello sugiere que hay un abandono del cultivo de especies nativas y que los campesinos están introduciendo nuevas especies (hortalizas y aromáticas) que tienen demanda en el mercado.