bluuebunny/crossref_metadata_2025 huggingface dataset:
Empiema subdural de origem odontogênica: relato de caso
Authors: Meurer Lucas Marques , Raffaele Regina Maria , Peruffo Letícia Bandeira , Baldo Mario Eduardo , Lacerda Caio Botelho Vieira de , Cavalcanti Herbert de Abreu , Gaetti-Jardim Ellen Cristina
Published: January 2022

Introdução: O Empiema subdural caracteriza-se pelo acúmulo de secreção purulenta entre as meninges, via de regra é associado à presença de infecções contíguas ao encéfalo ou face potencialmente disseminantes como a sinusite. Objetivo:  Relatamos aqui um caso raro de Empiema resultante de um processo infecioso de origem odontogênica. Relato de caso:  jovem de 17 anos do sexo masculino, admitido pelo Pronto Socorro da Associação Beneficente Santa Casa de Campo Grande MS, com suspeita de meningite bacteriana referindo quadro febril, cefaleia e fotofobia. Mediante avaliação multidisciplinar envolvendo as equipes de Medicina Intensiva, Odontologia Hospitalar e Cirurgia e Traumatologia Bucomaxilofacial pôde-se rastrear a origem da infecção e numa abordagem conjunta com a Equipe de Neurocirurgia proceder com a remoção dos focos infecciosos.
Qualidade do sono e fatores associados em acadêmicos de Medicina: revisão integrativa
Authors: Costa Larissa Daltoé Moreira da , Rodrigues Kiane Rayza Pompeu Cunha , Gouveia Neire Moura de
Published: January 2022

Introdução: O sono é classificado como um estado de consciência complementar ao quadro de vigília, contudo, esta revisão traz que em meio ao âmbito acadêmico, no qual ocorrem constantes estresses, os estudantes de medicina são uma classe visivelmente afetada por distúrbios do sono. Estes trazem aos estudantes consequências negativas em seu desempenho acadêmico. Objetivo: O presente trabalho se propõe a fazer uma revisão integrativa para traçar o perfil dos estudantes de graduação em Medicina, quanto a má qualidade do sono e verificar a relação com os principais fatores influenciadores. Métodos: Trata-se de uma revisão integrativa da literatura, na qual foram utilizadas as seguintes palavras-chave “estudante de medicina”, “sono” e “depressão” suas correspondentes em inglês. Foram incluídos apenas estudos com alunos do ensino superior do curso de medicina realizados nos últimos 10 anos. Foram incluídos artigos e literatura cinzenta de estudos observacionais, consultados desde o ano de 2000, sendo que os critérios de exclusão se pautam em estudos experimentais, descritivos e de revisão. Resultados: 100% dos estudos apresentavam por objetivo dissertar sobre a qualidade do sono e os fatores influenciadores deste especificamente nos estudantes de medicina, assim através dessa revisão percebe-se que a autocobrança realizada pelos estudantes de medicina leva aos distúrbios de sono nestes, sendo que, o uso de substancias/medicamentos são os principais fatores que influenciam diretamente na qualidade do sono dos universitários 32% (n=9), seguido pela sonolência excessiva diurna 25% (n=7) e distúrbios psiquiátricos gerais 21% (n=6). Considerações finais: Os estudantes de Medicina compõem um grupo susceptível aos transtornos do sono, em razão da carga curricular em horário integral, das atividades extracurriculares e da forte pressão e estresse, com exigência de alto rendimento e tempo demandado em estudos.
Os desafios da prática odontológica frente à COVID-19: uma revisão de literatura
Authors: Moura Ana Beatriz Rodrigues , Goes Vitor Nascimento , Palmeira Júlia Tavares , Freire Julliana Cariry Palhano , Dias Ribeiro Eduardo
Published: January 2022

Introdução: Diante da pandemia de COVID-19, o cirurgião-dentista assim como os demais profissionais de saúde são os mais expostos ao vírus, o que exige maior biossegurança nos atendimentos. Objetivo: Dentro desse contexto, o presente trabalho tem como objetivo avaliar os desafios da prática odontológica frente ao cenário de pandemia atual, enfatizando a atuação do cirurgião-dentista na prevenção do vírus e as adaptações necessárias no ambiente odontológico. Material e método: Trata-se de uma revisão de literatura realizada através da análise de artigos contidos nas plataformas LILACS, PubMed e Medline que cumprissem o intuito informativo da pesquisa. Resultados: A partir dos dados obtidos, observou-se que a COVID-19 apresenta como principais sintomas clínicos febre, tosse, espirros e coriza, em casos brandos. As vias de transmissão mais frequentes são a direta e por contato. A fim de identificar casos suspeitos o cirurgião-dentista deve medir a temperatura corporal do paciente e aplicar um breve questionário. Todo o percurso do atendimento deverá ser planejado com o intuito de reduzir os riscos de contaminação, desde a escolha dos instrumentais que serão utilizados até a execução do procedimento. Conclusão: Portanto, no atual cenário da pandemia, surgem novos desafios aos quais os profissionais devem responder com constante cautela no que se refere à biossegurança, devida capacitação com periodicidade e ética. No entanto, reforça-se ainda mais a demanda por atualização constante dos protocolos, com base nas evidências científicas mais recentes, para minimizar os riscos de transmissão do vírus.
Tratamento multidisciplinar para reabilitação estética anterior: relato de caso
Authors: Piassi Jonathas Eduardo Virgilio , Silveira Lucas Mendes , Dias Caldeira François Isnaldo , Pigossi Suzane Cristina , Rodriguez Larissa Santana
Published: January 2022

O tratamento reabilitador tem a finalidade de restaurar a harmonia facial e com isso devolver a autoestima do indivíduo, reinserindo-o à sociedade. Este trabalho teve como objetivo descrever uma abordagem multidisciplinar envolvendo reabilitação estética anterior com prótese fixa adesiva associada à cirurgia periodontal estética. O presente relato de caso foi conduzido na Clínica Integrada I da Faculdade de Odontologia da Universidade Federal de Alfenas na qual a paciente procurou atendimento queixando-se da aparência do sorriso. No exame clínico foi observado que a paciente apresentava restaurações classe IV em resina composta com aspecto clínico insatisfatório, desarmonia dos zênites gengivais, encurtamento das coroas clínicas além da ausência do dente 22, substituído por prótese provisória splintada nos dentes adjacentes. Dessa forma, foi realizada a seguinte sequência clínica: clareamento dental superior/inferior e gengivoplastia na região superior anterior. Após a cicatrização foi realizado o preparo dentário, moldagem, confecção e cimentação de duas coroas unitárias em cerômero nos dentes 11 e 12 e a confecção de uma protése parcial fixa de 3 elementos (21, 22 e 23) em cerômero reforçado com fibra de vidro. Ao final do tratamento, foi possível restabelecer a função e estética em uma abordagem de baixo custo que garantiu a satisfação da paciente. Assim, a associação das diversas modalidades reabilitadoras da odontologia, como a periodontia, prótese e dentística proporcionou à paciente o restabelecimento dos padrões oclusais normais, recuperação da saúde periodontal, além de garantir um sorriso harmônico.
Percepção de universitários de uma instituição de ensino superior do Alto Sertão da Paraíba - Brasil a respeito de agravos sistêmicos frente a infecções odontogênicas
Authors: Gomes Tharley , Oliveira Marcos Alexandre Casimiro , Sousa Raulison Vieira , Barnabé Luan Éverton Galdino , Oliveira Júnior José Klidenberg de
Published: January 2022

As infecções odontogênicas são processos causados por cárie dentária, infecções endodônticas, pericoronarite e doenças periodontais. Em casos evoluídos, pode ocorrer a disseminação para regiões importantes do corpo. O objetivo do presente estudo foi avaliar a percepção de universitários de uma Instituição de Ensino Superior (IES) do alto sertão paraibano sobre a evolução das infecções odontogênicas. O trabalho em questão refere-se a um estudo transversal, de natureza descritiva e quantitativa, o qual foi realizado com os universitários matriculados na Faculdade Santa Maria, de todos os cursos de graduação (exceto Odontologia) e de todos os períodos. Foi realizado por meio de um questionário on-line estruturado, aplicado através da plataforma Google Forms e composto de três etapas. Foram entrevistados 143 universitários de ambos os sexos, entre as idades de 18 a 54 anos, sendo a maior parte mulheres (83,9%) e a idade mais prevalente compreende os indivíduos entre os 18 a 30 anos (85%). Em relação ao conhecimento sobre cárie dentária, 97,2% responderam que conheciam a doença. Quando indagados sobre ao entendimento de como evitar a cárie e a gengivite, 77,6% dos alunos responderam que sabiam métodos para evitar o surgimento das doenças. Mais da metade dos alunos (55,9%) responderam que concordavam totalmente que a cárie dentária e um canal não tratado poderiam ocasionar a formação de conteúdo purulento. Os resultados sugerem que os alunos da Faculdade Santa Maria possuem um bom conhecimento relacionado a infecções odontogênicas e seus agravos. Porém, esse conhecimento é limitado, mostrando assim que o mesmo deve ser aprofundado.
Reabilitação estética em dente com descoloração escura da coroa ocasionada por traumatismo: relato de caso
Authors: Lopes Valéria do Carmo de Brito , Lima Karlos Eduardo Rodrigues , Mendes Talita Arrais Daniel
Published: January 2022

Pacientes com alteração cromática dentária tendem a apresentar queixas e insatisfação significativa. Tendem a apresentar autoestima baixa, a restrição em sorrir, e a dificuldade de inserir-se na sociedade. Os incisivos superiores são os dentes que são impactantes no sorriso, sendo que estes possuem a característica de dominância, assim, qualquer alteração pode ser notada mais facilmente. Quando essas alterações ocorrem pode-se lançar mão de tratamento reabilitador estético com uso de resinas compostas. Logo, o presente estudo objetivou evidenciar a reabilitação estética e funcional através de um relato de caso clínico, a efetividade de facetas diretas e recontorno cosmético em um paciente com que apresente alteração cromática em dentes anteriores. Trata-se de um relato de caso clínico no qual foi realizado o atendimento a um paciente do gênero masculino, onde se diagnosticou escurecimento dentário por trauma, assim sendo, realizou-se um planejamento virtual do sorriso incluindo cirurgia gengival e restauração com resinas compostas. Desse modo, obteve-se um enceramento diagnóstico a partir do planejamento e em seguida realizou-se uma gengivectomia dos dentes anteriores superiores. Após o período de cicatrização realizou-se a faceta dentária do dente 11, seguido de fechamento de diastema entre os dentes 11 e 21 com recontorno cosmético. Por fim, pode-se perceber o sucesso do tratamento no reestabelecimento do sorriso do paciente, bem como melhora na autoestima do mesmo.
Evaluation of hybrid threats to DU technologies transfer
Authors: Kartuzov Iegor
Published: January 2022

An object of this research is to evaluate the premises of transfer of dual use technologies appeared in Ukraine and other CIS countries. It aims to highlight a hybrid impact of political, historical and other potential barriers faced between technology offeror/recipient nowadays.
The investigated problem. Apart from the highlighted affect of political, historical and other potential barriers faced between technology supplier /recipient these days, the paper also discusses how the covid pandemic and democracy crisis on the global joined to and affect an efficiency, proper functioning and transparency of technology transfer process. The experience and practice show that the process of technology transfer is rather complicated, multi-leveled and involves more than two players. It is impacted with and follows few factors and conditions that constrain its success or failure at the end. It was shown that the development of dual use technologies continues in a quagmire of conflicting interests, in light of discussed factors therein, national security and export control rationales. For the time being, debates on dual use (DU) technologies and their misuse lack creativity and rather dim; political and diplomatic initiatives came finally to nowhere trying to find turnkey solutions, thus the discussed set of factors affecting the efficient transfer and strategic export control, is quite a challenge nowadays.
The main scientific results. The discussed therein factors imply the hybrid threat to transfer of technologies, closely interrelated and possess a profound significance, tho. From today and forward each step towards optimization of transfer should be carried out considering all groups and specifics of high level of science intensity of advanced technologies. Ukraine being a country with still transitional (from socialist to capitalist) type of economy, a mechanism for IP protection with regard to their scientific and technical results providing this necessary level of science intensity of technology, in the analyzed period of time has not yet been properly worked out and not enshrined in bylaws.
The result of this eresearch makes a solid background for further debates as to technology transfer in terms of political science and export control
The reconciliation of the development and implementation of police accountability in the United Kingdom
Authors: Yesufu Shaka
Published: January 2022

The objects of this research are: first, to explain some of the issues surrounding police accountability in the United Kingdom. Second, to make attempts in reconciling two opposing views as to whom police in the UK are accountable for? Third, to clarify the vagueness and ambiguous definitional concepts of the police constable, constabulary independence, and the use of police discretionary powers.

The author investigated the following problems: lack of police proper accountability, vague and ambiguous meaning of constabulary independence constable oath of office, and the use of police discretionary powers.

The main results of the research are: first, more clarity is needed as to whom is the British police accountable to? Second, a review of the current oath of office for police constable, the implementation of finding by previous committees set up by government: Lord Scarman, Rt Hon Christopher Patten, and Lord Nolan reports. Third, the monitoring of police officers' use of discretionary powers.

The area of practical use of the research: is for all citizens, directly or indirectly affected by police and safer communities. Criminal justice students in higher institutions and criminal justice practitioners, government officials, and policymakers.
FINANCIAL REPORTING QUALITY: HOW TO OPTIMIZE THE ROLE OF INTERNAL AUDIT
Authors:   Institut Bisnis dan Informatika Kesatuan., a Iriyadi , Fettry Sylvia ,   Universitas Katolik Parahyangan., Anzib Nuraini ,   Universitas Syiah Kuala., b Mariyam ,   Universitas Pembangunan Panca Budi.
Published: January 2022

The purpose of the study is to investigate the role of the internal audit function (IAF) in improving the quality of financial reporting. This is because the effectiveness of the FAIs role is often questioned considering its status as an employee who must serve two masters namely the board of directors and the audit committee as representatives of the board of commissioners. On the other hand, financial statements represent reports on the performance and quality of the companys management. The research method uses quantitative methods with multiple linear regression analysis. The research data is based on a questionnaire survey with purposively selected respondents from accounting, finance, auditing, and audit committee practitioners. The research findings indicate that the competence and objectivity of the IAF have a positive effect on the quality of financial reporting. Thus, to enhance the quality of financial reporting, internal auditors must be able to improve their competence and objectivity. Meanwhile, the most important quality of financial statements is the fundamental qualitative characteristics of faithful or honest representation by management. The results of this study answer doubt about the unique role of the IAF as a servant of the two masters, and implicitly the partnership with the audit committee enhances the check and balance function through the role of the IAF. The limitation of the study is that the low determinant coefficient which indicates that there are many other factors that affect the quality of financial reporting. For further research, it is recommended to add other factors and increase the number of sample respondents.
VALIDATION OF STABILITY INDICATING RP-HPLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF TELMISARTAN AND HYDROCHLOROTHIAZIDE CONTENT IN BULK AND PHARMACEUTICAL DOSAGE FORM
Authors:   Analytical Research & Development, Changzhou Pharmaceutical Factory,Changzhou-213018, China., Santosh Kumar P. , a Wuchen ,   Analytical Research & Development, Changzhou Pharmaceutical Factory,Changzhou-213018, China., Lei Wang ,   Analytical Research & Development, Changzhou Pharmaceutical Factory,Changzhou-213018, China., Abbas Zaheer ,   Formulation Research & Development, Changzhou Pharmaceutical Factory, Changzhou - 213018, China.
Published: January 2022

A simple, accurate, precise and rapid stability indicating reverse phase High performance chromatography method was used for estimation of Telmisartan and Hydrochlorothiazide in bulk and fixed-dose combination solid oral dosage form. The proposed analytical method has been validated for specificity, Linearity, Accuracy, Precision and Robustness. The chromatography was achieved in a GL science, Inertsil C8 (Length 125x Diameter 4.0mm Particle size 5Âµm) column with gradient flow. The optimal chromatographic condition consisted of mobile phase pH 3.0 at a flow rate of 1.2mL/min, with a column temperature of 40Â°C, run time 14 minutes and detector wavelength of 270nm.
STUDY OF HTA DISTRIBUTION NETWORK RELIABILITYIN NIAMEYCITY
Authors:   Electrical Engineering Department, Mines, Industry and Geology School, Niamey, Niger., Kosso Moustapha Attoumane , Talibi Soumaila Noma ,   Laboratory of Energy, Electronics, Electrotechnics, Automatics and Industrial Computing, Abdou Moumouni University (UAM), Niamey, Niger., Mahamadou Ousman ,   Electrical Engineering Department, Mines, Industry and Geology School, Niamey, Niger., Bouzou Moussa Brah ,   Electrical Engineering Department, Mines, Industry and Geology School, Niamey, Niger., Seibou Boureima ,   Electrical Engineering Department, Mines, Industry and Geology School, Niamey, Niger.
Published: January 2022

With the growth of demand for electrical energy, electrical networks are nowadays subjected to very high loads, sometimes beyond their capacity. This leads to their malfunction and their inability to meet expectations. But given the importance of electricity in our lives, this disruption cannot be tolerated for long, which leads distribution operators to implement maintenance programs to ensure continuity of service. However, these measures, although extremely important, are time consuming, costly and sometimes do not provide complete satisfaction, resulting in the absence of electricity to consumers. The study of reliability of medium voltage distribution network in Niamey allowed us to analyze the performance indices of latter. Indeed, we based ourselves on the number of incidents (opening of HV outlets) and their duration while taking into account the origin of the associated disturbances. In the light of this analysis, the reliability of lines is close to 95% only for a period of one (1) hour (h) and is almost zero beyond 100 hours of operation. As for maintainability, it is only guaranteed within a period of 10 hours after the occurrence of incident on network.
SPATIAL DISTRIBUTION AND SOCIO-ECONOMIC STATUS OF TRIBAL SETTLEMENTS IN THE WESTERN GHATS
Authors:   Karnataka Veterinary Animal and Fisheries Sciences University, Bidar., D.M Basavarajaiah , B. Narasimhamurthy ,   National Health Mission, Government of India (Formerly, NIE, ICMR, Chennai)., Prasad T.S Ganesh ,   Colleges of Forestry, UAHS (S), Ponnampet, South Coorg., Naik Jaya ,   Karnataka Veterinary Animal and Fisheries Sciences University, Bidar.
Published: January 2022

The Western Ghats, also known as Sahyadri is a mountain range that covers an area of 140,000 square km parallel to the Western coast of the Indian Peninsula .It traverses the states of Kerala , Tamilnadu , Karnataka ,Goa ,Maharashtra, and Gujarat. It is a UNESCO world heritage site and is one of the eight hottest hot spots of biological diversity in the world. It covers 5000 species of flowering plants ,139 mammals species ,508 birds species, and 179 amphibian species ,many discovered species live in the Western Ghats . At least 325 globally threatened species occur in this region. The region glitches many anthropogenic intervention like illegal mining, the establishment of human settlement and deforestation etc. From a Historical view, the Western Ghats is the home for tribes > 50 types of tribes are living in the Western Ghats from the anecdotal period. The majority of the tribal are largely dependent on forests for their livelihood. After the implementation of the forest policy , the tribal livelihood status really worsened in the Western Ghats , they are unable to meet the daily requirement of recommended food intake >2500 Kcl. After post-independence (73years ) of India many development programs are implemented in the tribal area for improvement of livelihood status , but as of calendar date they are facing many problems like economic instability , lack of literacy , lower level of quality of life and not politically empowered . In this context , in the interest of policy implication at the tribal area , the present study was undertaken to study the socioeconomic status and spatial distribution of tribal in the Western Ghats. This study practically helps the policymakers , planners of the policy, and researcher scholars to extrapolate the tribal settlement through the geo-spacing tag of tribal , socio-economic level, Knowledge and attitude of Conservation of Western Ghats at the population level .
TOPICAL MITOMYCIN C IN THE TREATMENT OF CONJUNCTIVAL SQUAMOUS CELL CARCINOMA ABOUT TWO CASES
Authors:   Hopital Des Specialites De Rabat- CHU IBN SINA., Fatima Ezahra Hjira , Afaf Er-Radi ,   Hopital Des Specialites De Rabat- CHU IBN SINA., Habiba Tazi ,   Hopital Des Specialites De Rabat- CHU IBN SINA., Ahmed Bouslamti ,   Hopital Des Specialites De Rabat- CHU IBN SINA., Louai Serghini ,   Hopital Des Specialites De Rabat- CHU IBN SINA., El. Hassan Abdallah ,   Hopital Des Specialites De Rabat- CHU IBN SINA., Amina Berraho ,   Hopital Des Specialites De Rabat- CHU IBN SINA.
Published: January 2022

These are two male patients, aged 56 and 75, respectively, who presented with an unilateral limbal-conjunctival tumor, after a corneoconjunctival excision of the tumor, the histological analysis was performed and established the diagnosis of conjunctival squamous cell carcinoma Purpose: To describe those two cases of conjunctival squamous cell carcinoma that was successfully treated with adjunctive topical Mitomycin C.
EXPERIENCIA CLINICA EN PROTESIS REVERSA DE HOMBRO EN CENTRO MEDICO NAVAL
Authors: Flores Espinosa Jesus , Alfonso Munoz Galguera Ruperto
Published: January 2022

Problem Statement: The total reverse arthroplasty of man is a suitable therapeutic option for shoulder osteoarthritis associated with cuff rotator tear, massive rotator cuff tear mainly, medializing the rotation center of the shoulder joint, thus replacing the supraspinatus, recovering degree of freedom of movement of the shoulder with the promising clinical results described in the literature, interest has arisen on the part of the traumatology and orthopedics service to evaluate the clinical evolution of the patients operated with this procedure, and generate the knowledge that can be integrated later in studies of May scientific validity. Objective: Objective: to describe the clinical outcome of patients undergoing surgery, with total reverse shoulder arthroplasty, after 6 months of surgery in a naval medical center. Methodology: Type of study: an observational, cross-sectional, retrospective study was carried out. Population: 8 patients que fueron intervenidos quirÃƒÂºrgicamente con artroplastia total reversa de hombro. The DASH, Constan and Simple Shoulder Test tests were applied, which were applied preoperatively and after 6 months of the surgical intervention, and the description and analysis of data was carried out with a statistical program. Results: there was clinical improvement in most patients on the DASH scale with average disability improvement of 59% to 36%, Constan scale from 25.7 to 49.6, Simple Shoulder Test from 3.1 to 5.6. Conclusion. The total reverse shoulder prosthesis is a suitable alternative with adequate clinical results for patients with rotator cuff tear, massive rotator cuff tear.
RENT NEGOTIATION BETWEEN COMMERCIALS AND LANDLORDS DURING THE COVID-19 PANDEMIC
Authors:   Research Scholar, Higher Institute of Management, University of Tunis., Kouki Dorsaf , Zarrad Houda ,   Assistant Professor, Marketing Department, Higher Institute of Management, University of Tunis.
Published: January 2022

The emergence of the coronavirus crisis has generated unexpected negative effects for most companies, specifically small enterprises. The objective of this research is to examine the effect of this pandemic on the rental negotiation process between commercials and landlords. Based on an in-depth literature review on negotiation and the phenomenon of the crisis, a quantitative study is carried out with a sample of 396 Tunisian respondents to validate our measurement model. The empirical results show that the integrative arrangement has a positive effect on the negotiation process, with a mediating role of the mediation variable. The latter exerts in turn, a positive effect on the social psychological result of the competitor. These findings led to a rich discussion and a set of managerial recommendations that can help commercials to respond more effectively to the challenges generated by the COVID-19 pandemic.
DIAGNOSTIC BRONCHOSCOPY FOR EVALUATION OF CONGENITAL STRIDOR:A CASE SERIES
Authors: Khurshid Hina , Y.R Chandrika , N Madhavi
Published: January 2022

Introduction: Stridor is a noise mechanically produced through partially occluded airway. Airway obstruction may be extrathoracic or intrathoracic. Stridor may be congenital or acquired. Timing in respiratory cycle determines anatomic location of lesion Â– inspiratory, biphasic, or expiratory. Gold standard for diagnosis is bronchoscopy which requires general anaesthesia in infants and small children. Major anaesthetic concerns are Â– possible difficult airway, sharing of an already compromised airway, airway oedema. Case Description: 40 infants, 0 - 6 months age, with history of noisy breathing suggestive of congenital stridor, planned for diagnostic rigid bronchoscopy with or without therapeutic procedure, over one year period. Preoperative treatment Â– humidified oxygen, nebulization, dexamethasone, antibiotics, anti-reflux medication. Not premedicated, standard monitors applied. Induction of anaesthesia with inhalational oxygen and sevoflurane or intravenous propofol, fentanyl 1 mcg/kg, dexamethasone 0.5 mg/kg. Topical lidocaine 2% sprayed at vocal cords. 100% oxygen with propofol infusion for maintenance with spontaneous ventilation via nasopharyngeal airway. Patients requiring surgical intervention intubated using microcuffed endotracheal tube. Patients observed post-operatively. If ventilation was inadequate, intubated to control airway during recovery, extubated on restoration of spontaneous ventilation. After surgical intervention, babies shifted to ICU for elective ventilation for 48 hours. Discussion: On bronchoscopy, laryngomalacia was the finding in majority of cases. Others had subglottic stenosis, tracheomalacia, vocal-cord paresis, laryngeal cyst. Out of 40 patients, 9 underwent therapeutic procedure and were electively ventilated, 26 resumed spontaneous breathing, 2 patients had delayed recovery and 2 had severe chest retractions and desaturations and they were managed accordingly. One baby aged 6 months diagnosed with grade III subglottic stenosis desaturatedand tracheostomy had to be done. Conclusion:Anaesthesia for rigid diagnostic bronchoscopy is a significant challenge. Rigid bronchoscopy under general anaesthesia requires multidisciplinary approach and close cooperation between all team members.
ANABOLIC STEROID ABUSE AND CARDIOVASCULAR TOXICITY: CASE REPORT
Authors:   CardiologyB ,CHUIbnSina Rabat, Faculty of Medicine And Pharmacy, Morocco., Hdioud Oussama , MD Benmessaoudfz ,   CardiologyB ,CHUIbnSina Rabat, Faculty of Medicine And Pharmacy, Morocco., Nawal MD Doghmi ,   CardiologyB ,CHUIbnSina Rabat, Faculty of Medicine And Pharmacy, Morocco., Latifa Oukerraj ,   CardiologyB ,CHUIbnSina Rabat, Faculty of Medicine And Pharmacy, Morocco., Cherti MD Mohamed ,   CardiologyB ,CHUIbnSina Rabat, Faculty of Medicine And Pharmacy, Morocco.
Published: January 2022

Despite the development of tests for the detection of doping, Anabolic steroids, are still used to increase sports performance. Unfortunately, studies have clearly shown that overdose of anabolic steroids can induce serious cardiovascular complications that can be life-threatening. This implies the determining role of health professionals in informing the general population and athletes in particular about the lethal effect of these substances. We report the case of a young high-level athlete who consults for palpitations and in whom cardiac imaging reveals abnormalities related to chronic consumption of anabolic steroids.
AWARENESS OF ANEMIA AMONG RURAL PREGNANT WOMEN IN BAGERHAT DISTRICT OF BANGLADESH
Authors:   MPSc in Applied Statistics, Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh., Abu Borhan Md. , Ayub Ali Md. ,   Professor, Department of Statistics, University of Rajshahi, Rajshahi-6205, Bangladesh.
Published: January 2022

Background: Anemia in pregnancyis a decrease in the total red blood cells (RBCs) or hemoglobin in the blood duringpregnancyor in the period following pregnancy. It is the condition of having a lower-than-normal number of red blood cells or quantity of hemoglobin. Anemia diminishes the capacity of the blood to carry oxygen. Patients with anemia may feel tired, fatigue easily, appear pale, develop palpitations, and become shortness of breath. Objectives: The purpose of the present study was to investigate about the awareness of anemia among rural pregnant women in Bagerhat district of Bangladesh Materials and Method: A sample of 29 pregnant women (PW) from a total of listed 111 women from three upazilas of Bagerhat district was considered for assessing the awareness of Anemia. Those three upazilas were taken at random first from the nine upazilas of Bagerhat district.Data on different variables were collected directly from the selected women through a prescribed questionnaire. Descriptive statistics e.g., maximum, minimum, mean, standard deviation, skewness, kurtosis, etc. of the variables together with their standard error of their estimates were considered foranalyzing sample characteristics of the study. The relationship between two nominal variables is assessed by cross tabulation with test statistics Phi and Cramers V. The bootstrapresampling method was used to understand the population parameters. Results: About86% pregnant women have no idea about anemia and also their causes. All respondents feel weakness that indicates they have the symptom of anemia. The phi andcramersV imply that the relationship between heard about anemia and the source of information is highly significant (p= 0.000). Among the awarded women in Bagerhat district, probability of getting awareness from service provider was0.917 and that from relatives was 0.083. Among the population, the probability of contribution of the service provider was0.379. Probability of unknown was 0.586 indicating much populationin Bagerhat district werenot aware about anemia. Probability of getting information of anemia from mother was zero indicating very recently service providers have started their program in Bagerhat district. Conclusion: Probability of getting information of anemia from mother is zero indicating very recently service providers have started their program in Bagerhat district. Therefore, this program should be continued until the probability of getting information from mother will be closed to 1. Recommendation: Government as well as the NGOs should continue & enhance the present awareness program in Bagerhat district.
FORMULATION AND INVITRO EVALUATION OF SOLID DISPERSION TABLETS OF SILYMARIN
Authors:   Associate Professor, Department of Pharmaceutics, MRM College of Pharmacy, India., Naz Ayesha , Kulsum Syeda ,   Professor, Department of Pharmaceutical Analysis, MRM College of Pharmacy, India., Begum Mehraj ,   Student, MRM College of Pharmacy, India., Omer Mohammed ,   Student, MRM College of Pharmacy, India., Naser Mohiuddin Syed ,   Student, MRM College of Pharmacy, India.
Published: January 2022

Objective: The research aims to formulate and evaluate Solid Dispersion tablets of Silymarin. Methods: Solid dispersions of Silymarin were prepared with various concentrations of carriers by using solvent evaporation method. The prepared solid dispersions were compressed into tablets by using 8 mm punch rotary tablet punching machine, with the hardness of 3.5kg /cm2.The formulated tablets were evaluated for various quality control parameters. Results: Silymarin was mixed with various proportions of excipients which showed no drug-excipients interactions. The precompression blend of Silymarin solid dispersions were characterized with respect to angle of repose, bulk density, tapped density, Carrs index and Hausners ratio. The precompression blend of all the batches indicated good to fair flowability and compressibility. Conclusion: The tablet passed all the tests. Among all the formulations F4 formulation containing, Drug and PEG 4000 in the ratio of 1:4 showed good result that is 94.95 % in 60 minutes. As the concentration of polymer increased the drug release was increased. While the formulations containing PEG 6000 showed less release. Hence from the dissolution data it was evident that F4 formulation is the better formulation.
C-REACTIVE PROTEIN/ALBUMIN RATIO AND NEUTROPHIL-LYMPHOCYTE RATIO AS PREDICTORS OF COVID-19 SEVERITY
Authors:   Professor, Department of General Medicine Dr. PSIMS &RF., Madhav M.V. , Sirisha Y. ,   Associate Professor, Department of Internal Medicine Dr. PSIMS &RF Chinnoutpalli, Gannavaram, Andhrapradesh., Anjaneya Prasad V. ,   HOD & Professor Department of Internal Medicine, Dr.PSIMS &RF Chinnoutpalli, Gannavaram, Andhrapradesh.
Published: January 2022

Coronavirus disease 2019 (COVID-19) was announced in early December 2019. By genome sequencing, the virus was recognised. From Wuhan City, the virus spread globally. The pandemic situation was declared by the World Health Organization.The first case of COVID-19 in Indiawas reported in Kerala on January 27, 2020.The clinical features varied with disease severity. Most COVID-19 patients have non-severe manifestations and show a good prognosis. However, patients with severe disease may progress to pulmonary dysfunction, multiple organ dysfunction, and death. COVID-19 related to a considerable mortality rate in older patients and cases had other morbidities. Studies suggested that the inflammatory storm is a common finding in other coronaviruses.Similarly, increases in the inflammatory markers like C-reactive protein (CRP),ferritin,interleukin-6 (IL-6) and were described in COVID-19 (1). Albumin levels decreased in the inflammatory conditions reduced levels were confirmed in severe COVID-19 patients. Hypoalbuminemia and high CRP/albumin ratio were previously linked to the mortality of various clinical conditions as critically ill patients.To avoid the unnecessary or inappropriate utilisation of the healthcare resources, early prediction of the severity of COVID-19 will be helpful. Severity prediction will also improve the prognosis by reducing the mortality rate.Thus, this study aimed to evaluate the role of inflammatory markers in estimating the severity and predicting the prognosis of COVID-19. This study hypothesised that elevated values of CRP/ albumin ratio and the neutrophil-lymphocyte ratio at the time of COVID-19 diagnosis are associated with COVID-19 severity and mortality.
A STUDY ON DOMESTIC INSTITUTIONAL INVESTMENTS AND ITS IMPACT ON MEJOR SECTORS OF ECONOMY
Authors: Kumar A. Prashanth , a Sumathi , R Shetty Sushmitha
Published: January 2022

India is a developing economy, which has undergone a series of developmental events in last two years. Covid -19 Pandemic has created a lot of challenges across various sectors of the economy. Major sectors of the economy has underwent a series of changes during this phase. IT industries adopted work from home as a long-term cost cutting strategy bringing in necessary changes in work culture. The government has also made all the possible efforts to keep up the phase of development in spite of the challenges posed by the pandemic. Pandemic gave a new dimension to the Indian stock market as many DII & FII became active leading to the further growth of the market in spite of the pandemic.The paper attempts to identify Impact of DIII in the Indian Stock Market. An attempt is made to study the relationship between Selected Nifty Indices movements, DII Inflow/Outflow, by evaluating their investments in equity, Debt and Future& Options segments by applying Statistical Tools. Thus,overall impact of these Players on the Stock Market & Economy is studied. Paper concludes suggesting the measures to identify the major players and empower them as it is necessary tobuild future developing India.
CSR COMMITMENT AND ACTION LOGICS OF SME MANAGERS: FINDINGS FROM A TUNISIAN STUDY
Authors:   PhD in Management University of Manouba, ISCAE, LIGUE, Code nÂ° LR99ES24. University Campus of Manouba 2010, Tunis., Mhissen Ines , Gherib Jouhaina ,   Professor of Management University of Manouba, ISCAE, LIGUE, Code nÂ° LR99ES24. University Campus of Manouba, 2010, Tunis., Berger-Douce Sandrine ,   Professor of Management Ecole des Mines de St-Etienne - Institut Fayol / EPICE, France158 cours Fauriel - CS 62362 - 42023 Saint-Etienne Cedex 2, France.
Published: January 2022

Purpose: Bymobilizing the sociological approach of action logic, this research aims to understand the articulation between the various dimensions of Corporate Social Responsibility (CSR) and the conditions for the emergence of an overallcommitment towards stakeholders in Small and Medium-Sized Enterprises (SMEs) in an emerging country: Tunisia. Design/methodology: A qualitative study was carried out through multiple case studies of Tunisian SMEs. Findings: The research findings tend to reveal that an overall CSR commitment requires an interaction between individual and contextual dimensions. However, predispositions coming from the individual manager dimension would play the role of a catalyst for a proactive CSR approach. As for the SMEs transition from weak to global commitment, this would primarily stem from contextual dimensions. In addition, each of the hedonistic, entrepreneurial or managerial action logic could be conducive to this type of commitment. Research Limitations:The number of explored cases could constitute a limitation of this work as it does not allow a statistical generalization of the results based on the criterion of frequency. Originality: Few of the CSR studies focused on a multi-dimensional commitment in SMEs In this research we aim to avoid an over-representation of the manager, and approach his action logics most conducive to a multi-stakeholder approach to CSR.
IMPACT OF COVID-19 PANDEMIC ON GASTROINTESTINAL ENDOSCOPY PROCEDURES
Authors: Gawade Sandesh , Sarvankar Divyangi , Chikhale Shivani
Published: January 2022

Background- COVID-19, an emerging coronavirus disease is a major health problem. It has markedly affected the routine medical procedures including Gastrointestinal(GI) endoscopies. Inspite of guidelines suggested by various GI societies,for safe GI endoscopy procedures in period of COVID pandemic, most of the endoscopists as well as the patients were hesitant for the endoscopy procedures.We sought to measure the impact of the same on GI endoscopy activity in Pune. Method- A pre-validated questionnaire containing 28 questions was sent across to the GI endoscopy surgeons. Responses were collected to assess the perception of GI endoscopists regarding the practice of endoscopy and the risk of self-contamination during COVID-19 Pandemic. This data was analysed using appropriate statistical applications. Result-51 GI endoscopists from Pune participated in our study out of which 80.3% (41/51) were involved in the management of COVID-19 patients outside the endoscopy department. During the study period, 86.28% (44/51) of endoscopists had to cancel procedures on grounds of COVID19 pandemic.Symptoms compatible with COVID-19 infection were reported by 29.41% (15/51) of the endoscopists out of which 13 (86%) responders had a positive RTPCR test for COVID-19 Conclusion- COVID-19 pandemic has seriously affected GI endoscopy practice. COVID 19 infection rate was also remarkable in endoscopists and endoscopy staff. As the screening of patients with GI problems was hampered, there was definitive delay in diagnosis and treatment. Nevertheless, endoscopy centers should adapt and make changes in their practice to face future pandemic, emphasizing safety of staff without delaying patient care.
Experience of using a thrombofibrin clot of plateletrich plasma in ulcerative lesions of the cornea
Authors: Fedoseeva E. V. , Chentsova E. V. , Borovkova N. V. , Ponomarev I. N. , Vlasova V. A. , Pavlenko Yu. A.
Published: January 2022

Purpose: to study the effectiveness of the use of thrombofibrin clot of platelet-rich plasma (PRP) in patients with corneal ulcers. Material and methods. A clinical study, conducted by the Department of Traumatology and Reconstructive Surgery of Helmholtz National Medical Research Center of Eye Diseases, involved 20 patients, aged from 22 to 82, with corneal ulcers of inflammatory and burn genesis more than 100 microns deep. All patients got coated with a thrombofibrin PRP clot from autologous blood. Prior to the study, all patients received standard treatment for 2 weeks to 3 months, including multiple amniotic membrane coating, with no effect. The thrombofibrin clot was produced by the Scientific Department of Biotechnology and Transfusiology of the N.V. Sklifosovsky Research Institute for Emergency Medicine. The ready clot was placed on the surface of the cornea and covered with an amniotic membrane. The membrane was fixed to the episclera along the border of the limb with a circular suture, whereupon autologous serum was injected along the limb in 4 quadrants, to be followed by temporary lateral blepharography. Results. On the 2nd day following the procedure, the patients noted a decrease in lacrimation and pain in the operated eye. As shown by optical coherence tomography, the average depth of the corneal ulcer at the beginning of the study in all patients was 129 ± 28.5 microns. On the 5th day, the depth lowered to an average of 71 ± 32.6 microns, and on the 10th day, to 23.3 ± 15.1 microns. In 7 patients (35%), complete healing of the defect was observed on the 15th day, while in 9 patients (45%) it was stated between the 16th and the 20th day. Thus, the average time of healing of the ulcer with complete epithelization occurred was 15 days. In four patients with the consequences of severe burns (20%), the ulcer did not heal due to extensive damage to the limbal zone. Conclusion. The use of a thrombofibrin PRP clot in combination with amniotic membrane transplantation allows achieving a stable and fairly rapid healing of corneal ulcers of various origins. However, this method is ineffective in patients with limbal cell insufficiency, severe burns and extensive damage to the limbal zone. In such cases, it is advisable to use more radical surgical methods, such as buccal or limbal cell transplantation, or allolimbal transplantation.
Efficacy of platelet-rich plasma lysate in the treatment of patients with post-traumatic eyelid scarring: an overview of clinical cases
Authors: Filatova I. A. , Pavlenko Yu. A. , Shemetov S. A. , Fedoseeva E. V. , Ponomarev I. N. , Borovkova N. V.
Published: January 2022

Purpose: to evaluate the effectiveness of platelet-rich plasma lysate (PRP) in the treatment of patients with post-traumatic eyelid scarring by clinical examples. Material and methods. Patients with post-traumatic scarring changes in eyelid tissues causing a damage in the functional and cosmetic state of the auxiliary apparatus of the eye were treated in the Department of Plastic Surgery and Eye Prosthetics at the Helmholtz National Medical Research Center of Eye Diseases. Two of the patients, who had been traumatized shortly before the examination and one patient who had rejected surgery were offered treatment by PRP lysate manufactured at the Sklifosovsky Medical Research Institute of Emergency Medicine. After local infiltration anesthesia, each patient received a single injection of PRP lysate (2 ml) into the scar tissue. The result was evaluated at a follow-up that took place 3 months after the injection. Results. The clinical picture of the three patients showed a pronounced positive dynamic of the functional and cosmetic state of the auxiliary eye apparatus, which made the patients reject subsequent (additional) surgical treatment. Conclusion. An improvement tissue repair and regeneration processes after PRP lysate injection allows us to assess this method as an applicable alternative of reconstructive operations in certain cases.
PRÁTICA EDUCATIVA: REFLEXÃO DO PROFESSOR NA PERSPECTIVA FREIRIANA NO CONTEXTO DA PANDEMIA
Authors: Claro Ana Lúcia de , Silva Lisandra Babireski Barcia da , Portilho Evelise Maria Labatut
Published: January 2022

Este artigo apresenta como objetivo realizar uma revisão teórica sobre a prática educativa na perspectiva de Paulo Freire no contexto da pandemia. Reflete, ainda, sobre a concepção de educação e o papel do educador na perspectiva libertadora. Para tanto, busca responder a seguinte questão-problema: quais são os elementos que devem nortear a prática educativa proposta por Paulo Freire? Como resultado, os estudos realizados mostram a necessidade de rever e refletir sobre a prática dos professores, especialmente em se tratando do contexto de crise sanitária provocada pela pandemia do novo coronavírus (COVID-19) atualmente vivenciada. Portanto, diante desses desafios, faz-se necessário estar presente na prática dos professores a efetividade do diálogo e da escuta ativa em torno das aprendizagens dos educandos, bem como uma reflexão contínua sobre o fazer pedagógico e sobre a práxis que se materializa na articulação da teoria e prática por meio de um processo dialógico de reflexão e ação transformadora da prática educativa.
ENTRE LA VIRTUD Y EL UTILITARISMO: UNA APROXIMACIÓN A LA EDUCACIÓN MORAL
Authors: Sánchez Pérez Yaiza
Published: January 2022

La reflexión sobre cuestiones relacionadas con la educación moral, ya no solo en su concepción teórica, sino en su puesta en práctica dentro de las aulas, es esencial para el correcto ejercicio de la profesión docente. Por este motivo, se analizan las aportaciones realizadas por Aristóteles y John Stuart Mill a la educación moral con el fin de construir una reflexión pedagógica que facilite la comprensión del desarrollo moral del alumnado en el contexto educativo actual. A partir de una perspectiva filosófica, se utiliza un método analítico basado en el estudio de los postulados de la ética de la virtud y el utilitarismo; concretamente en cuestiones relacionadas con el desarrollo moral de los sujetos, la felicidad o la importancia del razonamiento ante los conflictos morales para comprender qué aportaciones se pueden aplicar a la educación actual. Las principales conclusiones extraídas tras el estudio son la importancia de reflexionar críticamente en los centros educativos sobre conceptos como prudencia, virtud, felicidad o ciudadanía; así como la riqueza que aporta al debate educativo la incorporación de conceptos como la virtud. Además, desarrollar virtudes en el alumnado permitirá que conozcan el bien, lo deseen y lo practiquen.