bluuebunny/crossref_metadata_2025 huggingface dataset:
A Review on Puerulus (Panulirus spp.) Resource Utilization in Indonesia Based on the Sense of Hearing: Auditory Receptor Organs
Authors: Subagio Hari , Asrial Evron , Yusnaini Yusnaini , Rosana Nurul , Bintoro Gatut , Nuhman Nuhman , Kawan I Made
Published: September 2021

Highlight ResearchThe mortality of lobster seeds by predators in the first year is 96.0-99.4%It takes technology to catch seeds before being eaten by predatorsApplication of sound wave-based attractor technology to lobstersDo lobsters have the ability to hear sound waves?The lobster's sense of hearing begins to function from the puerulus stage AbstractIndonesia is a country that produces abundant lobster seeds (puerulus), however, there is a paradox, where natural mortality in the first year since entering the settlement phase can reach 96.0-99.4%. The use of lobster resources, especially in the puerulus stage, for cultivation, is very strategic. Therefore, it is necessary to improve puerulus fishing technology. In the capture fisheries sector, the use of the sense of hearing in fish resources has been carried out to increase catch productivity, by utilizing sound wave-based attractors’ technology. For lobster resources, to what extent is this technology applicable? Underwater sound waves are a phenomenon of compression and expansion of a medium as sound energy passes through it. This aspect of the study is still new and very prospective. The purpose of this review article is to answer some basic questions: Can lobsters be able to hear sounds that come from their surroundings, since when do lobsters sense of hearing begin to function, and anatomically what kind of auditory organs are in lobsters. The results of the review conclude as follows: lobsters have senses that are able to perceive or listen to sound waves (sound) from their surrounding environment, this ability has been possessed by lobsters since they were in the postlarva or puerulus stage. Anatomically, the organs that act as the sense of hearing in lobsters are: receptors on the body surface, chordotonal organs and statocyst organs.
Immobilization of Providencia stuartii Cells in Papaya Trunk Wood for N-acetylglucosamine Production from Pennaeus vannamei Shrimp Shells
Authors: Halim Yuniwaty , Tantradjaja Steven Fausta , Hardoko Hardoko , Handayani Ratna
Published: September 2021

Highlight Research AbstractChitin is a natural compound found abundantly in shrimp shells. Chitin can be degraded to produce N-acetylglucosamine, which has wide applications in the food and pharmaceutical fields. Fermentation using chitinolytic microorganisms can be used to produce N-acetylglucosamine from shrimp shells’ chitin. One of the strong chitinolytic bacteria that was isolated from previous research was Providencia stuartii. To provide better stability and efficiency in fermentation, P. stuartii cells were immobilized using entrapment method in papaya trunk wood. The aims of this research were to determine the optimum papaya trunk wood size, ratio of papaya trunk wood and growth medium, as well as the optimum fermentation cycle to produce N-acetylglucosamine from P. vannamei shrimp shells using submerged fermentation method. The research used experimental method with treatment of different sizes of papaya trunk wood (1 x 1 x 1 cm3, 1.5 x 1.5 x 1.5 cm3, and 2 x 2 x 2 cm3), different ratio of papaya trunk wood and growth medium (1:10, 1:15 and 1:20), and 4 fermentation cycles. Results showed that papaya trunk wood with size of 1 x 1 x 1 cm3 and ratio (w/v) of 1:10 could immobilize 87.08±2.05% of P. stuartii cells and produce the highest N-acetylglucosamine concentration, which was 238177.78±3153.48 ppm. The highest N-acetylglucosamine production was obtained from first fermentation cycle and decreased over the last three cycles, but still produced high concentration of N-acetylglucosamine. Therefore, it is possible to perform continuous N-acetylglucosamine production from shrimp shells using P. stuartii cells immobilized in papaya trunk wood.
REB’s statistical series: surveys of agricultural enterprises
Authors: Aukutsionek S. , Batyaeva A. , Dyomina N. , Egorov A. , Matveev A.
Published: September 2021

The article presents unique data on the Russian agricultural sector, which has been gathered by the Russian Economic Barometer for almost 30 years. There is published statistics reflecting the attitude of the heads of agricultural enterprises towards the economic policy of the government. There are presented data revealing the degree of importance for the agricultural producers of various factors limiting production and capital investments.
Monitoring and diagnosis of historical masonry buildings and future perspective = Monitoreo y diagnóstico de edificios históricos de mampostería y perspectiva futura
Authors: Preciado Adolfo , Colmenero Fabiola
Published: September 2021

AbstractHistorical buildings still existing in different parts of the world were constructed with unreinforced masonry and have an acceptable capacity to transmit vertical loading, but they are very vulnerable against horizontal loading induced by earthquakes. In order to protect these buildings belonging to the patrimony of the humanity from this hazard, we need to understand the construction materials, structural elements and loading transmission mechanism. Moreover, to rehabilitate or retrofit them, it is necessary to develop an understanding process of the structure though monitoring and in-situ/laboratory experimental tests to stablish a diagnosis. The structural monitoring campaigns are helpful to investigate the mechanical and dynamic properties of the building. The use of installed thermal cameras and micro-sensors at strategic parts of the historical buildings represent a very interesting and non-destructive option to measure different parameters constantly and for long periods of time. The present paper aims at briefly describing the different involved processes in the monitoring and structural diagnosis of historical buildings which is fundamental in order to preserve them against the effects of earthquakes by means of rehabilitation works and strengthening. Moreover, it is presented a future perspective about non-destructive and non-invasive experimental tests and diagnosis with the use of new technologies.ResumenLos edificios históricos que aún existen en diferentes partes del mundo fueron construidos con mampostería no reforzada y tienen capacidad aceptable para transmitir cargas verticales, pero son muy vulnerables ante cargas laterales inducidas por sismos. Para proteger de esta amenaza a estas edificaciones que forman parte del patrimonio de la humanidad, debemos de entender los materiales constructivos, elementos estructurales y su mecanismo de transmisión de cargas. Para decidir entre rehabilitar o reforzar, se debe de realizar un proceso de entendimiento de la estructura a través de un monitoreo y pruebas experimentales en sitio y en laboratorio que permitan generar un diagnóstico. Los monitoreos estructurales sirven para investigar sus propiedades mecánicas y dinámicas. El uso de cámaras térmicas y micro-sensores en puntos estratégicos de los edificios históricos representan una opción muy interesante y no destructiva para medir diferentes parámetros de forma constante y por largos periodos de tiempo. El presente artículo tiene como objetivo describir de forma puntual los diferentes procesos involucrados en el monitoreo y diagnóstico estructural de edificios históricos que resulta fundamental para poder conservarlos ante los efectos de los sismos por medio de trabajos de rehabilitación y refuerzo. Además, se presenta una perspectiva futura sobre pruebas experimentales y diagnósticos no destructivos ni invasivos con el uso de nuevas tecnologías.
Technology-Enabled Learning and Post-Pandemic Academic Scene in India: Some Reflections
Authors: Bora Merry Baruah
Published: September 2021

The onslaught of the Covid pandemic has changed the landscape of human interactions and life drastically; after the apparent changes in the health sector, the field of education has been radically changed.  This study makes an effort to deliberate upon some aspects of the National Education Policy, 2020(NEP) and Right to Education (RTE) in relation to the post-pandemic changes that have been seen in the present Indian educational scene especially in the context of the technology-enabled learning.
NUTM1-Rearranged Neoplasms: A Heterogeneous Group of Primitive Tumors with Expanding Spectrum of Histology and Molecular Alterations: An Updated Review
Authors: Luo Wenyi , Stevens Todd , Stafford Phillip , Miettinen Markku , Gatalica Zoran , Vranic Semir
Published: September 2021

Nuclear protein of testis (NUT), a protein product of the NUTM1 gene (located on the long arm of chromosome 15) with highly restricted physiologic expression in post-meiotic spermatids, is the oncogenic driver of a group of emerging neoplasms when fused with genes involved in transcription regulation. Although initially identified in a group of lethal midline carcinomas in which NUT forms fusion proteins with bromodomain proteins, NUTM1-rearrangement has since been identified in tumors at non-midline locations, with non-bromodomain partners and with varied morphology. The histologic features of these tumors have also expanded to include sarcoma, skin adnexal tumors, and hematologic malignancies that harbor various fusion partners and are associated with markedly different clinical courses varying from benign to malignant. Most of these tumors have nondescript primitive morphology and therefore should be routinely considered in any undifferentiated neoplasm. The diagnosis is facilitated by the immunohistochemical use of the monoclonal C52 antibody, fluorescence in situ hybridization (FISH), and, recently, RNA-Sequencing. The pathogenesis is believed to be altered expression of oncogenes or tumor suppressor genes by NUT-mediated genome-wide histone modification. NUTM1-rearranged neoplasms respond poorly to classical chemotherapy and radiation therapy. Targeted therapies such as bromodomain and extraterminal domain inhibitor (BETi) therapy are being developed. This current review provides an update of NUTM1-rearranged neoplasms, focusing on the correlation between basic sciences and clinical aspects.
Peering Into Avian Influenza A(H5N8) for a Framework towards Pandemic Preparedness
Authors: Yeo Joshua Yi , Gan Samuel Ken-En
Published: September 2021

2014 marked the first emergence of avian influenza A(H5N8) in Jeonbuk Province, South Korea, which then quickly spread worldwide. In the midst of the 2020-21 H5N8 outbreak, it spread to domestic poultry and wild waterfowl shorebirds, leading to the first human infection in Astrakhan Oblast, Russia. Despite being clinically asymptomatic and without direct human-to-human transmission, the World Health Organisation stressed the need for continued risk assessment given the nature of Influenza to reassort and generate novel strains. Given its promiscuity and spread to humans, the urgency to understand the mechanisms of possible species jumping to avert disastrous pandemics is increasing. Addressing the epidemiology of H5N8 and its mechanisms of species jumping and its implications, mutational and reassortment libraries can potentially be built, allowing them to be tested on various models complemented with deep-sequencing and automation. With the knowledge on mutational patterns, cellular pathways, drug resistance mechanisms and effects of host proteins can allow better preparedness against H5N8 and other influenza A viruses.
Women's issue in the prose of the 19th century in the context of the educational process
Authors: Lipnytska Inna , Savchenko Iryna , Halak Inna , Hryhorenko Iryna , Bykova Tetiana
Published: September 2021

The purpose of the article is to study the sources and pedagogical interpretation of the "women's question". The subject of the research is the “women's question” and its artistic realization in the novels of Marko Vovchok. The analysis of the problem was carried out by integrating the traditional methods of Russian comparative historical literary criticism with new approaches to world literary criticism - gender, sociocultural, postcolonial, and feminist. As a result of the study, we came to the conclusion that the pedagogical views on the "women's issue" in the writer were formed and developed under the influence of communication with the Ukrainian and European intelligentsia of the 19th century. The progressive part of the intelligentsia of the second half of the XIX - early XX century advocated a change in the social status of women. Representatives of public and pedagogical opinion believed that a woman can not only be a mother, wife, housewife, she is capable of self-realization in other areas of society, for which she needs a decent education. The journalistic work on this problem of women with a possible comparative characterization of the regions of some European countries, which in the period under study were part of the Austro-Hungarian empires, deserves further study
The Relations of Internal and External Factors with Women Farmers’ Participation in Rice Farming Activities
Authors: Pratiwi Dita , Baga Lukman Mohammad , Yusalina Yusalina
Published: September 2021

The participation of women in the agricultural sector has increased in the last two years, attributed to the population growth and household economy. Therefore, this research examined the internal and external factors to the women farmers’ participation. This research was conducted in Situ Gede Village, West Bogor Sub-district, Bogor City and involved women farmer group consisting of 36 members. The primary data were gathered by interviewing respondents using a questionnaire, while the secondary data were obtained from literature review and various related institutional sources. The data were examined using the Pearson’s Product-Moment Correlation analysis to investigate the relations between the internal and external factors to women farmers’ participation. The results of this study have revealed the internal factors related to women farmers’ participation, such as age, farm experience and decision making. Meanwhile, the external factor related to the participation of women farmers is the access to counseling, meaning that some of these aspects need to receive the government’s attention, especially in terms of access to education related to the counseling method, time and substance of counseling.
Factors Affecting the Participation of Sugarcane and Tobacco Farmers in Farmer Groups, Associations and Cooperatives in Indonesia
Authors: Rokhani Rokhani , Fauziyah Diana , Supriono Agus , Hariyati Yuli , Raharto Sugeng , Hapsari Triana Dewi , Adi Ad Hariyanto , Khasan Ahmad Fatikhul , Rondhi Mohammad
Published: September 2021

The revitalization of farmer organizations has become the central paradigm in agricultural development. In Indonesia, increasing farmer participation in farmer groups, associations and cooperatives is the strategy to revitalize farmer organizations. This study aimed to determine the factors influencing farmers' participation in farmer groups, associations and cooperatives. This study employed data from the Sugarcane and Tobacco Plantation Farm Household Survey in 2014, consisting of 8,831 (70.73%) sugarcane farmers and 3,645 (29.27%) tobacco farmers. Logistic regression analysis was used to identify the factors contributing to farmers' participation in each organization. The results showed that harvest area, access to extension and contract farming positively affect farmers’ participation in organizations. Farmers' age and education positively affect their participation in associations and cooperatives but do not significantly affect their group participation. Land tenure has an ununiform effect on farmer participation in each organization. Tenant farmers are less likely to participate in farmer groups and cooperatives, but they tend to participate in associations. Meanwhile, the owner farmers are less likely to join cooperatives. Government support positively influences farmer group participation, shows a negative effect on participation in associations and has a non-significant effect on participation in cooperatives. Finally, farmers' wealth gives a positive effect on their participation in cooperatives, a negative effect on their participation in associations and a non-significant effect on farmer groups. These results depict that farmer groups are more inclusive than cooperatives and associations.
Analysis of Marketing Margins and Farmers’ Shares on Corn in Sigi Regency, Central Sulawesi, Indonesia
Authors: Rahayu Heni Sulistyawati Purwaning , Dewi Mardiana , Abid Muhammad
Published: September 2021

An increase in corn productivity is not always followed by an increase in farmer income and welfare. The sustainability of farms must be supported by its economic viability including the marketing aspect. This study aimed to analyze the marketing of corn in Sigi Regency, Central Sulawesi Province. This research applied qualitative and quantitative methods. Marketing channel and marketing margin were analyzed descriptively, while farmer share was analyzed quantitatively using variance analysis (ANOVA). The results have shown three types of corn marketing channels, namely: 1) channel I, consisting of farmers-consumers, 2) channel II, covering farmers-collectors, traders-retailers and traders-consumers and 3) channel III, including farmers-collectors and traders- feed industries. Channel II has the highest marketing margin, followed by channel III and I, respectively. The intermediaries determine marketing costs that affect marketing margin and farmers’ shares. Channel I has the highest farmers’ shares, followed by channel III and channel II, respectively. The results of the significant difference test have revealed a difference in farmers’ shares in the marketing channels; and hence, the choice of marketing channel significantly determines the farmers’ shares. Therefore, farmers should shorten the marketing chain and strengthen their bargaining position by activating groups. Meanwhile, the government can play an active role so that farmers can have an access to strengthening capital and marketing.
Rainwater harvesting for fish farming water requirements in Boyolali Regency, Indonesia
Authors: Hadiani Rintis , Septiariva Iva Yenis , Solichin Solichin , Muttaqien Adi Yusuf , Sudarto Sudarto
Published: September 2021

Climate change causes dry and rainy seasons to shift. Hydrology also shows that the number of rainwater changes with the uncertainty of its potential occurrence. In catfish farming and hydroponic farming, ensuring water availability is important for the sustainability of the project. Existing research is about managing rainwater, which can help partially supply water for both projects' benefit. The research location is in Jeron Village, Nogosari District, Boyolali Regency. Boyolali Regency is a 22 % residential area of the total area. It means 570 m3 potential storage. However, the result shows that only 17% of the roof area can collect rainfall for residential houses. In this study's residential case example, 17% of the roof area gives 97.8 m3 / year. The problem is that currently, there is no Rain Water Harvesting (RWH). A system capable of supporting the water supply. Using RWH provides a benefit based on the potential supply.  This study highlights the potential benefits of using RWH. This pool yields a profit of up to (Indonesian Rupiah) IDR. 36,643,718 / month or IDR. 439,724.61 / year, with a probability of 80%. It means that in 5 years, it failed once. Moreover, water needs can supply from RWH.
Mini Special Issue on Tsunami Numerical Modeling Benchmarks – Challenges of Tsunami Modeling Hackathon –
Authors: Koshimura Shunichi
Published: September 2021

Numerical simulation and modeling became an essential technology in tsunami research and disaster management. Various numerical models were proposed and utilized for the development of tsunami risk assessment, inundation maps, and evacuation plans. The model verification and validation standards would be crucial to ensure sufficient reliability of tsunami risk assessment, inundation maps, as well as a consistency among various efforts. Common approach to ensure sufficient accuracy and reliability of numerical modeling is developing benchmark problems of hydraulic experiments and to use them for numerical model’s verification and validation.

To satisfy this requirement, “Tsunami Modeling Hackathon” was held in September 2020 to organize new benchmark problems in numerical modeling of tsunamis and to improve their reliability and accuracy. Hackathon is an intensive-gathering event of computer programmers and others involved in software development to create outcomes by the end of the event. This event was organized by Prof. Tomoyuki Takahashi of Kansai University and his colleagues, who led the tsunami research subcommittee in Japan Society of Civil Engineers (JSCE).

Tsunami modeling hackathon, in which about 23 teams and 162 researchers joined, included experiment and modeling teams in seven benchmark problems: urban tsunami inundation, landslide tsunami, tsunami loading on seawalls and coastal structures, sediment transport, drift of floating objects. The modeling groups performed the blind tests to cross-validate and interpret the results of their simulations in seven benchmark problems given by the experiment groups and discussed the improvement.

This special issue reports the outcomes of the tsunami modeling hackathon, and includes six papers (five in this issue, one in the regular issue). We hope this issue will provide useful insights for tsunami modelers and contribute to establishing a standardized way to ensure that various tsunami numerical models would be validated through the benchmark problems.
Comparisons of Numerical Models on Formation of Sediment Deposition Induced by Tsunami Run-Up
Authors: Yamamoto Ako , Kajikawa Yuki , Yamashita Kei , Masaya Ryota , Watanabe Ryo , Harada Kenji ,   Forestry and Forest Products Research Institute 1 Matsunosato, Tsukuba, Ibaraki 305-8687, Japan,   Social Systems and Civil Engineering, Tottori University, Tottori, Japan,   International Research Institute of Disaster Science (IRIDeS), Tohoku University, Miyagi, Japan,   Civil and Environmental Engineering, Graduate School of Engineering, Tohoku University, Miyagi, Japan,   Center for Integrated Research and Education of Natural Hazards, Shizuoka University, Shizuoka, Japan
Published: September 2021

Tsunami sediments provide direct evidence of tsunami arrival histories for tsunami risk assessments. Therefore, it is important to understand the formation process of tsunami sediment for tsunami risk assessment. Numerical simulations can be used to better understand the formation process. However, as the formation of tsunami sediments is affected by various conditions, such as the tsunami hydraulic conditions, topographic conditions, and sediment conditions, many problems remain in such simulations when attempting to accurately reproduce the tsunami sediment formation process. To solve these problems, various numerical models and methods have been proposed, but there have been few comparative studies among such models. In this study, inter-model comparisons of tsunami sediment transport models were performed to improve the reproducibility of tsunami sediment features in models. To verify the reproducibility of the simulations, the simulation results were compared with the results of sediment transport hydraulic experiments using a tsunami run-up to land. Two types of experiments were conducted: a sloping plane with and without coverage by silica sand (fixed and movable beds, respectively). The simulation results confirm that there are conditions and parameters affecting not only the amount of sediment transport, but also the distribution. In particular, the treatment of the sediment coverage ratio in a calculation grid, roughness coefficient, and bedload transport rate formula on the fixed bed within the sediment transport model are considered important.
Söke’nin İşgali ve İşgal Döneminde Rum Faaliyetleri
Authors: DOĞTEKİN Abdullah
Published: September 2021

Sisam Adası’nın hemen karşısında yer alan Söke, daha öncesinde olduğu gibi Millî Mücadele döneminde de Rum nüfusunun yol açtığı sorunlarla karşılaşacaktır. Özellikle Sisam Adası bu türden faaliyetleri yürüten Rumların yuvası haline gelmiştir. Yunanistan ve adalardan gelen Rum eşkıyalar, yerli Rum çeteleriyle birleşmek suretiyle işledikleri cinayetler sonucunda sadece can kaybına neden olmadılar. Soygun ve yağmacılık faaliyetlerinde de bulunarak Müslüman Türklerin eşyalarını ve hayvanlarını gasp ettiler. Söke’deki Rumlar işgal döneminde eşkıyalığın yanı sıra propaganda ve casusluk faaliyetlerinde de bulunarak düşmana bilgi taşımışlardır. Bu çalışmada, işgalden sonra Söke Rumlarının tutum ve davranışlarında meydana gelen değişimler ile Söke kazası ve civarında gerçekleşen Rum faaliyetleri ele alınacaktır. Anadolu toprakları karşısında yer alan Ege adaları, dün olduğu gibi bugün de önemli bir tehdit ve tehlike arz etmektedir. Makale, işgal döneminde Ege adalarındaki Yunan ve Rum faaliyetlerine de değinerek bu tehlikeye bir kez daha dikkat çekmeyi de amaçlamaktadır.
Developing conceptual models for assessing benefits and impacts of USACE activities on freshwater mussel communities
Authors: Herman Brook , Slack William , Swannack Todd
Published: September 2021

In this report, we describe how aspects of existing freshwater mussel indices of biological integrity can be modified to fit within the planning paradigm established for developing and certifying ecological models for U.S. Army Corps of Engineers’ planning purposes. Herein, we present examples of using freshwater mussels for biological monitoring, how to calculate their associated IBIs specific to their region of origin and their potential use in ecosystem restoration planning. Additionally, we present general conceptual models that may be used in ecological model development and environmental benefits analysis for projects that focus on freshwater mussel habitat restoration.
Accelerating the tactical decision process with High-Performance Computing (HPC) on the edge : motivation, framework, and use cases
Authors: Ruvinsky Alicia , Garton Timothy , Chausse Daniel , Agrawal Rajeev , Yu Harland , Miller Ernest
Published: September 2021

Managing the ever-growing volume and velocity of data across the battlefield is a critical problem for warfighters. Solving this problem will require a fundamental change in how battlefield analyses are performed. A new approach to making decisions on the battlefield will eliminate data transport delays by moving the analytical capabilities closer to data sources. Decision cycles depend on the speed at which data can be captured and converted to actionable information for decision making. Real-time situational awareness is achieved by locating computational assets at the tactical edge. Accelerating the tactical decision process leverages capabilities in three technology areas: (1) High-Performance Computing (HPC), (2) Machine Learning (ML), and (3) Internet of Things (IoT). Exploiting these areas can reduce network traffic and shorten the time required to transform data into actionable information. Faster decision cycles may revolutionize battlefield operations. Presented is an overview of an artificial intelligence (AI) system design for near-real-time analytics in a tactical operational environment executing on co-located, mobile HPC hardware. The report contains the following sections, (1) an introduction describing motivation, background, and state of technology, (2) descriptions of tactical decision process leveraging HPC problem definition and use case, and (3) HPC tactical data analytics framework design enabling data to decisions.
Gestión de la motivación y su impacto en el desempeño de los colaboradores del Grupo Integración Logística INLOG, 2021
Authors:   , Alvarez Rojas Luz Natalia
Published: September 2021

El objetivo del estudio fue determinar el impacto de la motivación (M) en el desempeño (D) de los colaboradores del Grupo Integración Logística Inlog, 2021. La presente investigación pertenece al diseño no experimental transversal, de tipo descriptivo correlacional y con enfoque cuantitativo. Se tomó como población a 100 colaboradores del Grupo Integración Logística Inlog. La muestra estuvo conformada por 80 colaboradores del Lima y Quito del Grupo Integración Logística Inlog. Los instrumentos obtuvieron un Alfa de Cronbach, M (0.778) y D (0.771). Los resultados indicaron una relación positiva moderada, con un Rho de Spearman (0.444), siendo la prueba significativa con un pvalor=0.000 < 0.05. Se concluyó que existe un impacto positivo de la motivación sobre el desempeño, es decir a mayor motivación, más alto es el desempeño de los colaboradores. Afirmando lo planteado por F. Herzberg (1959), así como lo descrito por Chiavenato (2018).
Clima organizacional y su relación con la satisfacción del cliente en la Empresa Ozonomedica
Authors:   , Rejas Phowell Dayane Wendy
Published: September 2021

El objetivo del estudio fue identificar la relación que existe entre el clima organizacional y la satisfacción del cliente en la empresa Ozonomedica en el distrito de la Molina del periodo 2021.La presente investigación fue de diseño no experimental, de tipo correlacional- descriptivo de corte transversal y de enfoque cuantitativo. Se tomó como población a los 100 trabajadores de la empresa de cara al público, la muestra estuvo conformada por 80 colaboradores de las diferentes áreas de servicio de la empresa. Los instrumentos obtuvieron un alfa de cronbach, CO (0.874) y SC (0.946). Los resultados indicaron una relación positiva alta moderada, con un Rho Spearman (rs=0,735), siendo la prueba significativa con un pvalor=0,000 por debajo de la trazada en el estudio. Finalmente se corrobora la hipótesis general planteada, el cual muestra que existe una relación significativa entre las variables, donde a mejor clima organización, mayor será la satisfacción del cliente.
The Impact of Histologies On Clinical Outcomes of Spinal Metastases Treated With Stereotactic Body Radiotherapy.
Authors: Guo Lanlan , Xu Qingqing , Ke Lixin , Wu Ziwei , Zeng Ziyi , Chen Lei , Lu Li‐Xia , Chen Yuanyuan
Published: September 2021

Background

With the life expectance prolonging, more cancer patients occurred spinal metastases. To evaluate the impact of histologies on outcomes of spinal metastases treated with stereotactic body radiotherapy (SBRT) and identify the correlated prognostic factors.
Methods

The authors retrospectively reviewed the records of all patients who underwent SBRT with no prior radiation for spinal metastases between October 2015 and October 2020 at Sun Yat-sen University Cancer Center. Propensity score matching (PSM) was applied to balance the distribution of related baseline characteristics. The endpoints included overall survival (OS), local control (LC), pain relief, and time to pain relief.
Results

A total of 202 consecutive patients with 345 spinal metastases were treated with a median follow-up time of 16.02 months (range, 0.73–57.90 months). The 1- and 2-year OS rates were 57% and 50%, respectively. The median survival was 35.63 months. A higher Karnofsky Performance Scale (KPS) score at consult predicted for better OS (P = 0.020). The presence of pain at enrollment assessed by the Brief Pain Inventory (BPI) predicted for worse OS (P = 0.038). The 1-year LC rate was 92.0%. The pain relief rate was 76.30% (103/135 patients). Younger age was identified to be prognostic for better pain relief (P = 0.037). In the univariate and multivariate analysis, no variable was independently associated with time to pain relief. As for toxicity, no Grade ≥ 3 toxicity was observed.
Conclusions

SBRT is feasible and appears to be an effective treatment paradigm for patients with spinal metastases, with limited accepted toxicities.
Quantum-Efficiency Enhancement and Mechanical Responsiveness of Solid-State Photoluminescence Materials Based on Uniaxial Cellulose Nanocrystal Arrays in Flexible Polymer via Assembly-Induced Emission
Authors: Liu Siyuan , Shi Zhenxu , Wang Xuhong , Gong Yanbin , Li Xijun , Jia Xin , Gan Lin , Huang Jin
Published: September 2021

Assembling cellulose nanocrystals (CNCs) can induce solid-state photoluminescence based on Stokes scattering. Such photoluminescence is free of photo-quenching and should have great potential in optical materials, whereas poor flexibility of assembled CNC arrays limits its applications. Here, a co-assembly of binary components including 1D nanoparticles and long-chain polymers had been explored to introduce the uniaxial CNC arrays into a transparent poly (vinyl alcohol) (PVA) membrane, which enhanced the mechanical properties, especially the stretchable property. Besides, the CNC assembly was controlled by adjusting the volume ratio between CNC and PVA. The result indicated that co-assembly with PVA could improve the uniaxial orientation of assembled CNC arrays, which played a crucial role in enhancing the emission quantum-efficiency (EQE) of CNC. Stretching the PVA/CNC membrane could furthermore induce an enhancement in EQE together with a gradual shift in emission wavelength. The mechanism study on that stimulation-response suggested that the enhancement and shift came from the change in the uniaxial orientation degree and periodicity of the CNC assembly, respectively. Since the stimulation-responsive enhancement in EQE (from ca. 40% to ca. 60%) can even be observed by naked eyes, we believe such cellulose-based materials can be widely used in optical sensors.
Hospital-prepared Low-dose Atropine Eye Drops for Myopia Progression Control using Atropine Sulfate Injection Diluted in Normal Saline and Lubricants
Authors: Wongwirawat Nuthida , Kuchonthara Nirachorn , Boontanomwong Sorrawit , Pongpirul Krit
Published: September 2021

BackgroundAs commercial low-dose atropine eye-drops for myopia progression control are available in some countries, in-house preparation by diluting the 0.1% atropine eye-drop with sterile water or normal saline has been a common practice. Atropine injection is readily available and could be a more feasible alternative.ObjectiveTo assess the properties of the in-house low-dose atropine eye-drops prepared by diluting the atropine injection in two solvents and tested in two temperature conditions.MethodThe 0.01% atropine eye-drops (15ml) were prepared by diluting atropine sulfate injection with normal saline and lubricant eye-drops and stored at room temperature and in a refrigerator. All samples were daily dropped for 12 weeks to mimic real-life use, one of which was assessed every two weeks for the biological contamination and chemical properties. The active substance was compared with freshly prepared samples at the 12th week.ResultsThe 0.01% atropine eye-drops contains no bacteria, fungi, or particulate matter. The levels of atropine sulfate on all samples were comparable to the freshly prepared samples at the 12th week, regardless of the solvents used or storage conditions.ConclusionThe low-dose atropine eye-drops prepared from readily available atropine sulfate injection at healthcare facilities could be alternative to commercial products.
A Retrospective Study of Commercial Software System EDose in QA Application based on the Electronic Portal Imaging Device
Authors: Duan Xiaojuan , Dai Hongya , Li Yongqin , Zhou Yibing
Published: September 2021

Purpose: To evaluate the functions about the pre-treatment dose verification and, the in vivo dose verification for the commercial software EDose system based on Electronic Portal Imaging Device (EPID) retrospectively and establish the action limit level. Methods: The results of pre-treatment dose verification were compared with 2D array Seven29 and 3Dmap for 50 randomly selected IMRT plans of different lesions. A retrospective analysis was conducted for 287 radiotherapy plans using the EDose in pre-treatment dose verification, including 53 IMRT and 247 RapidArc plans, to establish the action limit level with statistical significance evaluation. 28 head and neck patients with different lesions were selected randomly for studying 3D online dose verification preliminary.Results: For pre-treatment dose verification, 50 plans’ average γ passing rates of the 3%/3mm criterion were > 98% for EDose, Seven29, 3Dmap, and 3%/2mm, 2%/2mm criteria were > 95%, 90%. The average γmean of the three verification methods were similar for the 3%/3mm criterion (0.35, 0.38, 0.35). Based on the 287 patients’ clinical data, the average γ passing rate was 97.5%, and the recommend clinical action level was established at 92% with a 95% confidence limit. The in vivo results showed that the γ pass rate had a decreasing trend as the 33 treatment fractions progressed. The γ passing rates means±SD of the first fraction was (91.92±3.31)% while the 33th fraction was (85.73±8.75)%. In addition, the standard deviation between the TPS calculations and the EDose measurement results indicated a higher value of the thirty-third treatment for PTVs and organ at risk compared to the first treatment.Conclusions: This study demonstrated that the EDose system is an accurate, efficient method for quality assurance of patient’ radiotherapy plans with remarkable consistency of treatment planning system (TPS).
Choroidal Thickness in Lipoid Proteinosis
Authors: Özgür Armağan , An Isa
Published: September 2021

Purpose: To assess choroidal thickness in patients with lipoid proteinosis versus healthy subjects using enhanced depth imaging optical coherence tomography. Methods: 40 eyes of 20 patients and the same number of age and sex-matched healthy individuals were enrolled. Comprehensive ocular examinations including measurement of best-corrected visual acuity, spherical equivalent values of refractive errors, and axial length were performed. Choroidal thickness at three points (subfoveal, 500 µm nasal and temporal regions) were measured. Results: The mean age was 15,68 ± 5,98 years in the patient group and 16,48 ± 5,69 years in the control group. Mean choroidal thickness was statistically significantly thicker at each point in patients with lipoid proteinosis compared to the healthy controls: subfoveal, temporal and nasal choroidal thickness measurements were 414,13 ± 53.88, 359.97 ± 64.75, 322.10 ± 56.74 in the study group; 341.60 ± 42.01, 329.55 ± 41.30, 295.44 ± 43.07 in the control group, respectively ( P < 0.05). Conclusion: Patients with lipoid proteinosis have thicker choroid compared to control eyes. Hyalin deposition and ensuing potential inflammation in the disease process may explain this finding.
Understanding the Needs of People With Rare Dementias and Recommendations for Improving Post-diagnostic Care: ‘There Is No Such Thing as One Size Fits All’
Authors: Giebel Clarissa , Cannon Jacqueline , Smith Sandra , Pearson Anna
Published: September 2021

People with rare dementias such as Lewy Body dementia show different symptoms to those with Alzheimer’s dementia. Due to the large proportion of people with Alzheimer’s dementia, most services are designed to support their needs and often neglect those of people with rarer dementias. The aim of this study was to understand the needs of people with rare dementias and their families to develop targeted support. Two care professional focus groups were held in the North West of England. Focus groups lasted up to 60 minutes and were subsequently transcribed and analysed via thematic analysis. One former carer for her husband with a rare dementia was an active member of the project team and helped design the interview schedule, interpret and disseminate the findings. 18 dementia care professionals took part. Thematic analysis generated six themes: (1) Complex needs unsupported; (2) Reluctance to approach services; (3) Lack of service adaptation to both people living with dementia and carers; (4) Lack of communication between service providers; (5) Environment of service provision; (6) Funding issues. As opposed to suggesting new types of social activities, focus groups identified significant barriers in approaching and using post-diagnostic for those affected by a rare dementia, as well as inequalities in access to care services. There are various personal and service barriers for people with rarer dementias and unpaid carers to accessing and using post-diagnostic services. Future implementation work needs to adapt services and identify ways in which to overcome barriers in approaching services.
Dinitrogen Cleavage and Hydrogenation to Ammonia with a Uranium Complex
Authors: Maron Laurent , Xin Xiaoqing , Douair Iskander , Wang Shuao , Zhu Congqing , Zhao Yue
Published: September 2021

The Haber–Bosch process produces ammonia (NH3) from dinitrogen (N2) and dihydrogen (H2), but requires high temperature and pressure. Before iron-based catalysts were exploited in the current industrial Haber–Bosch process, uranium-based materials were used as effective catalysts for production of NH3 from N2. Although some molecular uranium complexes are capable of combining and even reducing N2, however, further hydrogenation with H2 to NH3 has not yet been reported. Here, we report the first example of N2 cleavage and hydrogenation with H2 to NH3 with a molecular uranium complex. The N2 cleavage product contains three uranium centers that are bridged by three imido μ2-NH ligands and one nitrido μ3-N ligand. Labeling experiments with 15N demonstrate that the nitrido ligand in the product originates from N2. Reaction of the N2-cleaved complex with H2 or H+ forms NH3 under mild conditions. A synthetic cycle has been established by the reaction of the N2-cleaved complex with TMSCl. The isolation of this trinuclear imido-nitrido product implies that a multimetallic uranium assembly plays an important role in the activation of N2.
Ten-Year Trends of Adult Trauma Patients in Denmark from 2010 to 2019: A Retrospective Cohort Study
Authors: Trier Frederik , Fjølner Jesper , Raaber Nikolaj , Sørensen Anders Høyer , Søndergaard Rasmus , Kirkegaard Hans
Published: September 2021

Background: Trauma causes a considerable economic and societal burden and the trauma patient population and its prognosis changes over time. The aim of this study is to analyze ten-year trends of trauma patients at a major trauma center in Denmark. Methods: 5366 patients aged ≥ 16 years with Injury Severity Score (ISS) > 0 admitted by trauma team activation at Aarhus University Hospital Trauma Center between January 1, 2010 and December 31, 2019 were included. Descriptive statistics, incidence rate calculation, parametric and non-parametric test were used. An annual percent change with 95% confidence interval was used to estimate trend in mechanism of injuries. Multiple logistic regression with mortality as outcome were adjusted for age, sex and ISS. Results: The median age increased from 37 in 2010 to 49 in 2019 and the proportion of patients aged ≥ 65 doubled. The incidence of minor injuries (ISS 1-15) decreased from 181.3/105 inhabitants in 2010 to 112.7/105 in 2019 corresponding to an incidence rate ratio between 2019 and 2010 of 0.62 (95% CI: 0.54 to 0.72). Severe injuries (ISS > 15) increased from 10.1/105 inhabitants in 2010 to 13.6/105 in 2019 corresponding to an incidence rate ratio between 2019 and 2010 of 1.35 (95% CI: 1.04 to 1.76). The proportion of patients with ISS > 15 increased from 18.1% in 2010 to 31.1% in 2019. Multivariable logistic regression showed lower 30-day mortality for all trauma patients with ISS > 0 over the study period when adjusting for age, sex and ISS (Odds ratio: 0.94, 95% CI: 0.90 to 0.99). The 30-day mortality for severely injured patients with ISS > 15 decreased during the study period when adjusting for age, sex and ISS (Odds ratio: 0.92, 95% CI: 0.87 to 0.97). Fall injuries increased with an annual percent change of 4.1% (95% CI: 2.3% to 6.1%). Conclusions: Ten-year trends of trauma patients in Central Denmark Region show an increasing median age, injury severity and number of fall injuries. The 30-day mortality of trauma patients decreased for both minor injuries and severe injuries when adjusting for age, sex and injury severity. Trial registration: Not applicable.
Salinity reduces coastal marsh respiration more than photosynthesis
Authors: Kominoski John , Neubauer Scott , Bremen Ryan , Camacho Antonio , Camacho-Santamans Alba , Charles Sean , Cherry Julia , Gaiser Evelyn , Gedan Keryn , Helton Ashley , Herbert Ellen , Ishtiaq Khandker , Kirwan Matthew , Krauss Ken , Lamb-Wotton Lukas , Morant Daniel , Noe Gregory , Osland Michael , Solohin Elena , Troxler Tiffany , Tully Kate , Wilson Benjamin
Published: September 2021

A paradigm in carbon cycling science predicts that sea-level rise will enhance carbon accumulation in an apparent negative carbon-climate feedback1,2. However, ecosystems exposed to combinations of stressors and subsidies – such as saltwater intrusion and sea-level rise – may adapt, transition to an alternative state, or experience a decline in functions, such as carbon storage, thereby altering their response trajectories to environmental changes3,4. Climate change is increasing salinity in coastal ecosystems worldwide yet the effects on ecosystem metabolism remain uncertain4-8. Here, we synthesized gross ecosystem productivity (GEP), ecosystem respiration [CO2 and CH4 (ERCO2 and ERCH4)], and net ecosystem productivity (NEP) from diverse coastal marshes exposed to experimental additions and observational gradients in salinity. Increases in salinity generally caused decreases in median GEP, ERCO2, and ERCH4 but increases in GEP and NEP from ~5 to 10 ppt. Increased saltwater intrusion can stimulate or stress wetlands based on relative exposure and acclimation to increased salinities, and we detected positive NEP where salinity increases had greater negative effects on ERCO2 and ERCH4 than GEP. Although increases in NEP are detectable at low salinities, saltwater intrusion and climate-driven disturbances may reduce carbon storage capacity of coastal ecosystems as productivity declines toward higher salinities.
The Role of Entrepreneurship in Changing The Employment Rate in The European Union
Authors: Anastasiou Athanasios , Argiri Vasiliki , Komninos Dimitrios , Dermatis Zacharias , Papageorgiou Christos
Published: September 2021

The aim of this research is to examine the concept of entrepreneurship in the context of modern economic realities by presenting features and factors that contribute to economic growth. High unemployment, low economic growth and shrinking investment are key features of the long-term economic crisis at both national and European level.New entrepreneurship, combined with the strengthening of the existing one, is a powerful antidote to the fight against unemployment, as it provides the opportunity, mainly to young people, to innovate and create new products and services contributing to the wider economic and social whole, reducing unemployment while creating the right conditions for a remarkable and outward-looking economy. Taking into account the literature research, it is examined how the development of entrepreneurship actually contributes to the encouragement of economic activity, creating a favorable ground for growth in all sectors of the economy and the creation of new jobs.