bluuebunny/crossref_metadata_2025 huggingface dataset:
Mitigation of crosstalk between RSB and LSB signals generated by one I/Q modulator
Authors: Pan Xiaolong , Zhang Bo , Liu Xiangyu , Zhang Hongxin , Wang Kaihui , Zhang Yuemin , Ran Dongsheng , Wang Xishuo , Wang Chuxuan
Published: January 2020

Optical independent sideband (ISB) signals can be generated by exploiting one external In-phase/Quadrature (I/Q) modulator. Our theoretical analysis shows crosstalk between the two ISB (right and left side) signals can attribute to two main imperfections: amplitude difference and phase unmatched in I/Q data. To reduce the impact of crosstalk between the two ISB signals, we propose three schemes. The first is precise phase match of the I and Q data. The second has been made possible by setting different frequencies for the left sideband (LSB) and the right sideband (RSB) signals, and the last is achieved by adding Multiple-Input Multiple-Output (MIMO) equalization digital signal processing (DSP) at the receiver side. Our experimental results have shown that these schemes can improve the performance of ISB signals. In our experimental system we designed dual ISB system with different modulation formats in two sidebands. Precise phase match can bring a ∼2.2dB improvement at BER of 1×10−2 and a ∼4.3dB improvement at BER of 1×10−3 for 16-ary quadrature-amplitude-modulation (16QAM) and quadrature-phase-shift-keying (QPSK) signals, respectively, in 4Gbaud with carrier frequency of 36GHz system. The BER of 4Gbaud 16QAM ISB signal at 30GHz and 4Gbaud QPSK ISB signal at 38GHz can reach hard-decision forward-error-correction (HD-FEC) when the input power is larger than −5.5 and −7.4dBm respectively in different frequencies system. For 4Gbaud with carrier frequency of 36GHz system, the BER of 16QAM signal and QPSK signal reduce ∼2.1 and ∼2.2dB at HD-FEC after using MIMO. In addition, MIMO can further improve the performance of the matched phase system or the system with different frequencies.
Spectrally selective energy-saving coatings based on reactively sputtered bismuth oxide thin films
Authors: Al-Kuhaili M. F. , Daoud M. E. , Mekki M. B.
Published: January 2020

Spectrally selective coatings are multilayer structures that are deposited on glass. These structures consist of a metal/dielectric bi-layer, in which the metal is silver and the dielectric is a wide-bandgap semiconductor with a high refractive index. These layers are typically very thin (< 30 nm), and thus may be etched away if deposited by a sputtering process. This work has two objectives. First, a new design is fabricated that can sustain the sputtering process. Second, a high-refractive-index material (i.e., bismuth oxide) is selected to serve as the dielectric. Bismuth oxide is deposited by reactive direct-current sputtering, and the deposition parameters are optimized to yield films that are suitable for use in spectrally selective coatings. When used in a silver-based multilayer structure, the resulting peak visible transmittance was 68%, and the maximum infrared reflectance was 85%.
Hubungan HbA1c dengan Lingkar Pinggang, Rasio Lingkar Pinggang-Tinggi Badan, Indeks Massa Tubuh, dan Lingkar Lengan Atas pada Remaja Perempuan Overweight/Obesitas
Authors: Indrawati Febry Dwi , Moelyo Annang Giri , Soebagyo Bambang
Published: January 2020

Latar belakang. Obesitas memiliki risiko terhadap penyakit kardiovaskular dan metabolik. Lingkar pinggang (LP), rasio lingkar pinggang-tinggi badan (RLPTB), indeks massa tubuh (IMT), dan lingkar lengan atas (LiLA) merupakan indeks antropometrik untuk menentukan obesitas sentral dan berkaitan dengan kadar insulin. Pada orang dewasa, distribusi lemak di sekitar pinggang adalah prediktor yang valid dari kadar hemoglobin A1c (HbA1c). Pengukuran ini memiliki kelebihan dibandingkan dengan tes glukosa darah puasa dan toleransi glukosa oral karena mudah dan murah.Tujuan. Untuk menentukan korelasi antara level HbA1c dengan lingkar pinggang, rasio lingkar pinggang-tinggi badan, indeks massa tubuh, dan lingkar lengan atas.Metode. Penelitian potong lintang ini dilakukan di SMP 4 Surakarta, data diperoleh secara consecutive sampling. Siswi overweight dan obesitas yang memenuhi kriteria termasuk dalam penelitian ini. Subjek menjalani pengukuran LP, RLPTB, IMT, LiLA, dan tes darah untuk kadar HbA1c. Semua data dianalisis dengan menghitung uji korelasi dengan signifikan <0,05.Hasil. Dua puluh sembilan siswi overweight/obesitas berpartisipasi dalam penelitian ini. HbA1c dan lingkar lengan atas memiliki korelasi positif dalam kategori sedang (r=0,580; p=0,001). HbA1c tidak berhubungan dengan LP (r=0,044; p=0,821), RLPTB (r=0,060; p=0,758), dan IMT ( =0,007; p=0,971).Kesimpulan. Lingkar lengan atas memiliki korelasi positif yang signifikan dengan kadar HbA1c pada remaja yang overweight dan obesitas.
Kadar Feritin Serum Terhadap Fungsi Paru pada Pasien Talasemia β Mayor
Authors: Dewi Luh Gde Ayu Pramitha , Mestika Mayangsari Ayu Setyorini , Subanada Ida Bagus , Purniti Putu Siadi , Widnyana AANKP
Published: January 2020

Latar belakang. Talasemia merupakan penyakit anemia hemolitik herediter akibat defek genetik pembentukan rantai globin. Tata laksana talasemia dengan transfusi darah dapat menimbulkan penumpukan besi di berbagai jaringan seperti paru. Tujuan. Untuk mengetahui korelasi kadar feritin serum terhadap fungsi paru pada anak talasemia β mayor.Metode. Studi analitik potong lintang dilakukan di RSUP Sanglah sejak Juli-Agustus 2017. Subjek diambil secara konsekutif dengan kriteria inklusi semua anak talasemia usia ≥6 tahun, mendapatkan transfusi darah rutin dan kelasi besi. Kriteria eksklusi adalah anak penderita talasemia dengan penyakit paru kronis dan tidak kooperatif saat spirometri.Hasil. Dari total 31 pasien talasemia di RSUP Sanglah, 28 subjek memenuhi kriteria inklusi dan tidak ada yang memenuhi kriteria eksklusi. Pada penelitian ini median usia pasien talasemia 12,5 tahun dengan kadar rerata feritin serum 3196,5 g/dL. Hasil spirometri dengan median vital capacity (VC) 75%, force vital capacity (FVC) 82,5%, force expiratory volume in one second (FEV1) 80,6%, FEV1/FVC 101,9%. Korelasi kadar feritin serum terhadap semua parameter fungsi paru yaitu VC, FVC, FEV1, dan FEV1/FVC adalah sangat lemah dengan masing-masing nilai r adalah (r=0,016; p=0,936), (r=0,181; p=0,357), (r=0,305; p=0,114), (r=0,158; p=0,42).Kesimpulan. Korelasi kadar feritin serum terhadap semua parameter fungsi paru didapatkan korelasi lemah dan tidak bermakna secara statistik.
Perbandingan Penggunaan Heated Humidified High Flow Oxygen Therapy dan Low Flow Oxygen Therapy pada Pasien dengan Hipoksemia: Tinjauan Kasus Berbasis Bukti
Authors: Nursakina Yosilia , Prawira Yogi
Published: January 2020

Latar belakang. Selama ini, penggunaan low flow oxygen therapy sebagai terapi pada pasien dengan hipoksemia memiliki angka kegagalan terapi yang tinggi dan toleransi pasien yang rendah. Literatur menunjukkan bahwa heated humidified high flow oxygen therapy dapat memperbaiki oksigenasi, angka keberhasilan terapi, dan kenyamanan pasien.Tujuan. Membandingkan efek penggunaan heated humidified high flow oxygen therapy dengan low flow oxygen therapy.Metode. Penelusuran literatur secara terstruktur dilakukan melalui Pubmed®, ScienceDirect®, Proquest®, dan EBSCO®.Hasil. Didapatkan dua studi acak terkontrol dan satu studi pendahuluan yang relevan. Ketiga studi menunjukkan bahwa heated humidified high flow oxygen therapy memiliki angka keberhasilan terapi yang lebih tinggi daripada low flow oxygen therapy dengan nilai NNT berturut-turut 5,55, 5,00, dan 9,09. Tidak ada perbedaan durasi rawat inap, kecepatan pernapasan, dan saturasi oksigen yang signifikan pada ketiga studi tersebut.Kesimpulan. Penggunaan heated humidified high flow oxygen therapy terbukti aman dan meningkatkan angka keberhasilan terapi pada pasien dengan hipoksemia.
Entre Saberes, Identidades e Territórios
Authors: Santos Rita Silvana Santana dos , Palavizini Roseane . , Catalão Vera Margarida Lessa
Published: January 2020

RESUMO

Este artigo visa promover a reflexão sobre processos educativos comprometidos com a sustentabilidade, resultantes dos saberes, sentidos e significados construídos nas relações das pessoas com/nos territórios que integram. A partir de perspectivas transdisciplinares e complexas da realidade, discutimos sobre a diversidade cultural na construção da governança de bens comuns, os sentidos e significados atribuídos aos saberes, valores e práticas trazidos pelos diferentes sujeitos e culturas e, por fim, as implicações do currículo como importante espaço-tempo na legitimação dos diferentes sistemas de conhecimento. As ideias convergem para integração de saberes, identidades e culturas que interagem nos territórios como basilares para formas sustentáveis de viver.

Palavras-chave: Transdisciplinaridade; Educação Ambiental; Territórios; Identidades; Currículo.

ABSTRACT

This article aims to promote reflection on educational processes committed to sustainability, resulting from the knowledge, meanings and meanings built in the relationships of people with / in the territories they integrate. From transdisciplinary and complex perspectives of reality, we discuss about cultural diversity in the construction of governance of commons, the meanings and meanings attributed to the knowledge, values and practices brought by different subjects and cultures and, finally, the implications of the curriculum as important space-time in the legitimation of different knowledge systems. The ideas converge to integrate knowledge, identities and cultures that interact in the territories as basic to sustainable ways of living.

Keywords: Transdisciplinarity; Knowledge; Environmental education; Territories; Identities; Curriculum.
The Use of Enrofloxacin Antibiotic as a Veterinary Drug and Its Residual Hazards on Public Health
Authors: Widiyanti Prima Mei , Sudarwanto Mirnawati Bachrum , Sudarnika Etih , Widiastuti Raphaella
Published: January 2020

The livestock sector can improve the community's economy and has a role in fulfilling food needs, especially animal protein. One of the problems in the livestock sector is the presence of infectious diseases that consequently need treatment using veterinary drugs. This paper describes the use of enrofloxacin antibiotics as veterinary drug and their residual hazards on public health. Enrofloxacin is an antibiotic from the family of fluoroquinolones (second generation of quinolone). Enrofloxacin is a broad-spectrum antibiotic that is effective to kill Gram positive and negative bacteria, so it was used for the treatment of various diseases in animals. Pharmacokinetically, enrofloxacin will be metabolized into ciprofloxacin and other metabolites. The improper use of enrofloxacin antibiotics caused residues in food products of animal origin, microbial resistance and toxicity, therefore the use of enrofloxacin needs to be monitored and evaluated for the sake of animal health and society.
Mitigasi Non Revenue Water (NRW) Sistem Jaringan Distribusi pada District Meter Area (DMA) Zona Kota Blahbatuh PDAM Gianyar
Authors: Yekti Mawiti Infantri , Gede Pebriarta Pratama Ida Bagus , Ngurah Purbawijaya Ida Bagus
Published: January 2020

The most common problem with drinking water supply is Non Revenue Water (NRW). NRW can be grouped into two types, namely physical water loss and non-physical water loss. This study aims to determine the NRW size, NRW causes, counter measures that can be done to suppress NRW. The results of evaluation of distribution networks that occur in the Blahbatuh City Zone District Meter Area (DMA) PDAM Gianyar. The difference between the amount of water distributed and the amount of water recorded in the account is NRW. The way to find out the cause and control of NRW is to analyze the results of the step test, UFM test (Ultrasonic Flow Meter), and conduct the interviews with employees of PDAM. The evaluation of distribution networks is only done in DMA Pande that has completed data. The amount of NRW that occured in the Blahbatuh City Zone is 474,142.83 m3/year (59.91%). The water loss is caused by damage to pipe accessories, leaky pipes, inaccuracies in the accuracy of the water meter. The water loss can be overcame by establishing a DMA, replacing pipe accessories, calibrating and replacing water meters. The evaluation results for the existing conditions of the distribution network in DMA Pande of Blahbatuh City Zone have not worked optimally. It seen from the results of the waternet and from the number of SR’s that have not met the requirements for the formation of a DMA.
Analisis Nonlinier Tekuk Torsi Lateral pada Balok Baja Cellular
Authors: Hung Benny Gunawan , Suryoatmono Bambang
Published: January 2020

One of many buckling modes that could occur on the beam is lateral-torsional buckling. Lateral torsional buckling could result in lateral deformation and torsion of section. In the AISC 360-16 Spesification, an equation is provided to calculate lateral-torsional buckling critical moment of prismatic I section beam. For cellular beams (I section beam with circular openings), AISC Design Guide 31 states that the lateral-torsional buckling critical moment should be checked in accordance with AISC Specification using gross section properties. With this assumption, thus, the design guide ignores the existence of circular opening on the web, which can cause a reduction of lateral-torsional buckling critical moment. In this study, lateral-torsional buckling analysis on cellular beam with simple support loaded by distributed transversal load has been done - the analysis utilized finite element based software. From the analysis, the critical moment is lower than AISC 360-16 critical moment with the assumption of prismatic I section beam, with the maximum difference percentage of 43,58%. Based on this study, a correction factor has been obtained to estimate the critical moment of cellular beams by using equation on AISC 360-16.
Longitudinal effects of task performance and self-concept on preadolescent EFL learners’ causal attributions of grammar success and failure
Authors: Faber Günter
Published: January 2020

Learners’ academic self-concepts and attributions have been widely evidenced to substantially regulate their educational development. Develop­men­tally, they will not only oper­ate in a mu­tually reinforcing manner. Rather, self-concepts will di­­­­rectly affect learners’ out­come attri­bu­­tions in a particular academic set­ting. Current research in the English as a foreign language (EFL) context has increasingly anal­­yzed learners’ attributions and self-concepts on a task-spe­­cific construct level. Never­the­less, there still exist certain research gaps in the field, partic­ularly con­cerning learners’ gram­mar self-con­cept and attributions. There­fore, the present study aimed at anal­yzing lon­gi­tu­dinal re­­lat­ions of prior performance and self-concept with subsequent attri­bu­tions of gram­mar suc­cess and failure in a samp­le of preadolescent EFL learners. Findings demonstrated that attri­bu­tional pat­terns most­­­­ly but not en­tire­ly depended on learn­ers’ grammar self-concept. Poor per­­form­ing learn­ers hold­ing a low self-concept dis­­played a maladaptive attri­bu­tion pattern for ex­­plain­ing both gram­­­mar suc­cess and failure. Though not with respect to all causal factors, these findings largely con­firm the crucial role of task-spe­cific self-concept in longitudinally explaining re­­lated control beliefs in the EFL con­text.
Application of Thermal Resistant Gemini Surfactants in Highly Thixotropic Water-in-oil Drilling Fluid System
Authors: Liu Yonggui , Zhang Yang , Yan Jing , Song Tao , Xu Yongjun
Published: January 2020

Traditional water-in-oil drilling fluids are limited by their shear thinning behavior. In this article, we propose the synthesis of a thermal resistant quaternary ammonium salt gemini surfactant DQGE-I. This surfactant was synthesized using monomers such as N,N-dimethyl-1,3-propanediamine, organic acids and epichlorohydrin, as well as blocking groups such as N-vinylpyrrolidone (NVP). The prepared surfactant exhibited various advantages over traditional surfactants, including excellent thermal stability, good emulsifying and wetting capability. The use of these surfactants was shown to improve the compactness of emulsifier molecules at the oil/water interface, as well as the overall emulsificaiton effect. Laboratory studies revealed that water-in-oil emulsions prepared using DQGE-I showed high emulsion breaking voltage, low liquid precipitation and small and uniformly distributed emulsion drops. Highly thixotropic water-in-oil drilling fluids based on DQGE-I showed low viscosity, high shear rate and thermal tolerance up to 260oC. Additionally, the proposed fluid was applied in 16 wells (including WS1-H2, GS3 and XS1-H8) in the Daqing Oilfield. Testing showed that DQGE-1 exhibited excellent rheological behavior and wall-building capability. The emulsion breaking voltage exceeded 1500 V, and the yield point/ plastic viscosity ratio exceeded 0.4. The use of this surfactant can help to solve problems such as high formation temperature and poor well wall stability.
Technical Solutions for Legal Challenges: Equality of Arms in Criminal Proceedings
Authors: Quattrocolo Serena , Anglano Cosimo , Canonico Massimo , Guazzone Marco
Published: January 2020

The paper focuses on how computational models and methods impact on current legal systems, and in particular, on criminal justice. While the discussion about the suitabilty of the exploitation of learning machines and Artificial Intelligence (AI) either as surveillance means and human substitutes in the judicial decision-making process is arising, the authors reflect upon the risk of using AI and algorithm-based evidence in criminal proceedings. The claim of the paper is twofold: on the one hand, we should reinterpret todays legal frameworks, e. g. the European Convention of Human Rights, shifting the attention from possible violations of the right to privacy to potential infringements on a basic fair trial feature, the Equality of Arms. On the other hand, we should aknowledge that main legal issues, triggered by the breathtaking advancements in AI, can properly be addressed mainly through technical solutions (e. g. methods for assessing the completeness and correctness of digital evidence related to mobile devices and conversations). No legal theory, which overlooks the crossover of juridical and computational expertise, will survive the present time.
No Path to New Economics: John Komlos’s Foundations of Real-World Economics (Komlos 2019)
Authors: Gorbatenko Daniil
Published: January 2020

John Komlos’s Foundations of Real-World Economics is an ambitious book that aims at taking down the foundations of modern mainstream economics that students are taught at Econ 101 classes and replace them with a more reality-based alternative. However, Komlos’s falls way short of the stated objective. First, he fails to genuinely engage the introductory textbooks with which he supposedly argues. Komlos also appears to misunderstand the purpose of introductory-level economic models like perfect competition, as well as to entertain the idea that their rejection may lead to different conclusions from those that he seems to favor. Finally, Komlos does not cite sufficient research and evidence for his own potential building blocks for a new economics, such as the claim that the basic assumption of scarcity should be scrapped in favor of that of abundance.
Information Literacy Self-Efficacy of Business Students in Pakistan
Authors: Asif Naveed Muhammad , Mahmood Madiha
Published: January 2020

This study aimed to investigate the information literacy (IL) self-efficacy of business students in Pakistan using a cross-sectional survey research design. The data were collected through a questionnaire containing an information Literacy Self-Efficacy Scale along with personal and academic variables. The results revealed that the business students were confident and competent in basic IL skills whereas they were less comfortable in developing and limiting search strategies, referencing, managing citations, using different types of libraries and lacking advanced levels of IL skills. In addition, there was no correlation of students’ perceived IL self-efficacy with gender, social background, ICT trainings received, and IL instructions received. Conversely, the students’ age, program of study, stage of study, and ICT proficiency appeared to be predictors of IL self-efficacy. The results generated pragmatic insights which can be used as a guide in developing useful directions for a need-based information literacy curriculum as well as programs.
New handy and accurate approximation for the Gaussian integrals with applications to science and engineering
Authors: Sandoval-Hernandez Mario A. , Vazquez-Leal Hector , Filobello-Nino Uriel , Hernandez-Martinez Luis
Published: January 2020

In this work, we propose to approximate the Gaussian integral, the error function and the cumulative distribution function by using the power series extender method (PSEM). The approximations proposed in this paper present a high accuracy for the complete domain [–∞,∞]. Furthermore, the approximations are handy and easy computable, avoiding the application of special numerical algorithms. In order to show its high accuracy, three case studies are presented with applications to science and engineering.
Revenue Sharing Vertical Contracts in the Movie Industry: A Theoretical Analysis
Authors: Baranchuk Nina , Seetharaman Seethu , Strijnev Andrei
Published: January 2020

For many years, the movie industry has been characterized by a unique (compared to other industries) type of vertical contracting practice, called sliding-scale contracting whereby the distributor (studio) takes a much larger (usually around 70%) share of box-office revenues than the exhibitor (theater) in the week of a movie’s release, with the exhibitor’s share increasing, in gradual steps, over subsequent weeks. In this paper, we propose a game-theoretic model that provides a new rationale for these contracting choices. Specifically, we show that these contracts effectively resolve conflicts of interest between studios and theaters over movie release timing and display length, in a way that is beneficial for both parties. Our model also stipulates conditions under which sliding scale become dominated by aggregate deals, i.e. deals based on total rather than weekly box office revenue. The testable predictions based on these conditions can be used by future empirical research once the available evidence on the use of aggregate deals in practice goes beyond anecdotal.
pH‐controlled histone acetylation amplifies melanocyte differentiation downstream of MITF
Authors: Raja Desingu Ayyappa , Gotherwal Vishvabandhu , Burse Shaunak A , Subramaniam Yogaspoorthi J , Sultan Farina , Vats Archana , Gautam Hemlata , Sharma Babita , Sharma Sachin , Singh Archana , Sivasubbu Sridhar , Gokhale Rajesh S , Natarajan Vivek T
Published: January 2020

Tanning response and melanocyte differentiation are mediated by the central transcription factor MITF. This involves the rapid and selective induction of melanocyte maturation genes, while concomitantly the expression of other effector genes is maintained. In this study, using cell‐based and zebrafish model systems, we report on a pH‐mediated feed‐forward mechanism of epigenetic regulation that enables selective amplification of the melanocyte maturation program. We demonstrate that MITF activation directly elevates the expression of the enzyme carbonic anhydrase 14 (CA14). Nuclear localization of CA14 leads to an increase of the intracellular pH, resulting in the activation of the histone acetyl transferase p300/CBP. In turn, enhanced H3K27 histone acetylation at selected differentiation genes facilitates their amplified expression via MITF. CRISPR‐mediated targeted missense mutation of CA14 in zebrafish results in the formation of immature acidic melanocytes with decreased pigmentation, establishing a central role for this mechanism during melanocyte differentiation in vivo. Thus, we describe an epigenetic control system via pH modulation that reinforces cell fate determination by altering chromatin dynamics.
PCAF‐mediated acetylation of ISX recruits BRD4 to promote epithelial‐mesenchymal transition
Authors: Wang Li‐Ting , Liu Kwei‐Yan , Jeng Wen‐Yih , Chiang Cheng‐Ming , Chai Chee‐Yin , Chiou Shyh‐Shin , Huang Ming‐Shyang , Yokoyama Kazunari K , Wang Shen‐Nien , Huang Shau‐Ku , Hsu Shih‐Hsien
Published: January 2020

Epigenetic regulation is important for cancer progression; however, the underlying mechanisms, particularly those involving protein acetylation, remain to be fully understood. Here, we show that p300/CBP‐associated factor (PCAF)‐dependent acetylation of the transcription factor intestine‐specific homeobox (ISX) regulates epithelial–mesenchymal transition (EMT) and promotes cancer metastasis. Mechanistically, PCAF acetylation of ISX at lysine 69 promotes the interaction with acetylated bromodomain‐containing protein 4 (BRD4) at lysine 332 in tumor cells, and the translocation of the resulting complex into the nucleus. There, it binds to promoters of EMT genes, where acetylation of histone 3 at lysines 9, 14, and 18 initiates chromatin remodeling and subsequent transcriptional activation. Ectopic ISX expression enhances EMT marker expression, including TWIST1, Snail1, and VEGF, induces cancer metastasis, but suppresses E‐cadherin expression. In lung cancer, ectopic expression of PCAF–ISX–BRD4 axis components correlates with clinical metastatic features and poor prognosis. These results suggest that the PCAF–ISX–BRD4 axis mediates EMT signaling and regulates tumor initiation and metastasis.
PCAF, ISX, and BRD4: a maleficent alliance serving lung cancer malignancy
Authors: Stemmler Marc P
Published: January 2020

Tumor progression and malignancy are frequently associated with aberrant activation of epithelial–mesenchymal transition (EMT), which orchestrates dramatic changes in gene expression, involving genetic and epigenetic regulation. External stimuli generated by tumor–stroma interactions need to be adequately processed to specifically alter expression of key EMT transcription factors and associated genes. In this issue of EMBO Reports, Wang and colleagues demonstrate how epigenetic modifiers are utilized to induce EMT and metastasis [1]. Acetylation of intestine‐specific homeobox (ISX) by p300/CBP‐associated factor (PCAF) induces a cascade that results in Snail and Twist activation through histone modifications by a novel complex of PCAF, ISX, and bromodomain‐containing protein 4 (BRD4). These findings open novel possibilities of therapeutic intervention to inhibit EMT and metastasis in lung cancer.
TheDrosophilaPost-mating Response: Gene Expression and Behavioral Changes Reveal Perdurance and Variation in Cross-Tissue Interactions
Authors: Newell Nicole R , Ray Surjyendu , Dalton Justin E , Fortier Julia C , Kao Joyce Y , Chang Peter L , Nuzhdin Sergey V , Arbeitman Michelle N
Published: January 2020

Examining cross-tissue interactions is important for understanding physiology and homeostasis. In animals, the female gonad produces signaling molecules that act distally. We examine gene expression in Drosophila melanogaster female head tissues in 1) virgins without a germline compared to virgins with a germline, 2) post-mated females with and without a germline compared to virgins, and 3) post-mated females mated to males with and without a germline compared to virgins. In virgins, the absence of a female germline results in expression changes in genes with known roles in nutrient homeostasis. At one- and three-day(s) post-mating, genes that change expression are enriched with those that function in metabolic pathways, in all conditions. We systematically examine female post-mating impacts on sleep, food preference and re-mating, in the strains and time points used for gene expression analyses and compare to published studies. We show that post-mating, gene expression changes vary by strain, prompting us to examine variation in female re-mating. We perform a genome-wide association study that identifies several DNA polymorphisms, including four in/near Wnt signaling pathway genes. Together, these data reveal how gene expression and behavior in females are influenced by cross-tissue interactions, by examining the impact of mating, fertility, and genotype.
El aporte del turismo a la economía costarricense: más de una década después
Authors: Benavides Vindas Shirley
Published: January 2020

En el año 2005, se publicó el último artículo relacionado con el aporte del turismo a la economía costarricense. Por ello y por la importancia de esta actividad para el país, se ha considerado su actualización y ampliación del análisis de los resultados generados, más de una década después de la primera publicación. Se trabajó con datos de fuentes oficiales, tanto nacionales como internacionales, que garanticen la confiablidad de la información generada, para el análisis en esos dos niveles. Se presenta un contexto internacional y el comportamiento de una serie de variables que posibilitan determinar el aporte a la economía costarricense. Las dos actividades que más aportan al turismo y a la economía en general son: los “productos característicos del turismo” y “servicios conexos del turismo”. Estas son generadas, en su mayoría, por microempresas, con los riesgos que eso implica por ser las de más vulnerabilidad en el parque empresarial. El mayor productor y generador de valor es el relacionado con el “alojamiento” y, en segundo lugar, las “otras industrias conexas al turismo”, las cuales posibilitan más y mejores encadenamientos productivos. Según el Banco Central de Costa Rica, el PIB turístico para el año 2016, último dato que se tiene, fue de 1 554 928 millones de colones [correspondientes a US$ 2 712,6 millones], que representa un valor agregado a la producción interna de un 6,3 %, aunque por el potencial que el país tiene, por la variedad de recursos y territorios, este aporte podría ser mucho mayor.
Guidelines for the Research of the Lithuanian Catholic Church Metrics Books
Authors: Garliauskas Vidas
Published: January 2020

The metrics books of the Lithuanian Catholic Church are a heritage treasure of the whole nation. Up until the 20th century there were approximately 600 churches in Lithuania and each church had more than a dozen metrics books on average which means there could be up to 10 000–15 000 metrics books remaining in various archives. Due to the soviet occupation the church archives were damaged and metrics books were scattered to various unclear locations. Due to these unfortunate historical situation metrics books research has only begun and the books themselves are not yet fully catalogued. Some research on metrics books has been done by Zigmas Zinkevičius, Vitalija Macijauskienė, Jonas Palionis and others. Historians have shed some light on metrics book archives in various archives. It is clear that individual important research work has been done but an overall targeted research is lacking. A priority objective is to create a state wide data base of all catalogued metrics books. Second steps would be complex research of the metrics books including creation of a theoretical information base, creation of various data bases, use of the metrics books for localized research and etc. Successful research of metrics books is only possible if specific guidelines are followed. That is why this publication includes methodical instructions for researches to use when uncertain situations are encountered. The publication includes two cases of metrics books research. In the first example a couple of unique excerpts are presented with comments. The second one reconstructs the picture of the Suginčiai (Molėtai district) estate and town community during the 17th century. It includes residents of the estate, newlyweds, families and other persons). Philological notes on names are also included.
Publication of a Church Metrics Fragment (1705–1710) Which Is Part of the Oldest Remaining Original Stakliškiai Church Baptism Metrics Dated 1705–1726
Authors: Kaminskas-Krinčius Algimantas
Published: January 2020

Transcriptions of the Stakliškiai church metrics can be found dated from 1699 to 1798 while originals are available from 1705 to modern times. The article presents a church metrics fragment (1705–1710) which is part of the oldest remaining original Stakliškiai church baptism metrics dated 1705–1726. This period was chosen because in 1710 the plague made fundamental changes in the demographic situation of the town and other neighboring settlements. The main aim of the publication is to present the text not only semantically but also graphically. The entries are ordered this way: first column – the day, second column – name of the town, third column – the year, month and the whole text of the entry: name of the baptized baby, names of the parents, names of the godparents, area information and other additional notes e.g. information on the nobility of those present at the ceremony. The presented fragment is not only important to researchers of the specific town and area but also could serve as an example for preparing and researching other metrics books. Metrics books are important not only to genealogy researches but also to researchers of local history and specialists of demographics, linguistics or religious sciences.
Sectoral Analysis of the Determinants of Corporate Capital Structure in Malaysia
Authors: Peng Chow Yee
Published: January 2020

This study investigates the determinants of corporate capital structure of various sectors in the Bursa Malaysia Main Market with the aim to establish whether the determinants of capital structure can be explained by either the trade-off or the pecking order theory. This study also examines whether there are any differences between the regressions for any two sectors or not. This study applies both the ordinary least squares (OLS) and the seemingly unrelated regression (SUR) estimators to estimate the leverage models, and subsequently determines the efficiency of each estimator. The results indicate that profitability, asset tangibility, growth opportunities, and firm size are important determinants of corporate capital structure. However, the signs of the regression coefficients suggest that the trade-o and pecking order theories are complementary. Moreover, the importance of some of these determinants differs across sectors. In most cases of the regression analyses between two sectors, the SUR estimator is found to be more efficient in explaining the determinants of capital structure among the various sectors. Hence, this study concludes that the SUR method could serve as a useful alternative methodology for capital structure research.
Impact of Agency Costs on Firm Performance: Evidence from Vietnam
Authors: Hoang Le Duc , Tuan Tran Minh , Nha Pham Van Tue , Nha Pham Van Tue , Phuong Ta Thu
Published: January 2020

An assumption in agency costs theory is that agency costs can exert a negative impact on firm performance. In this study, we examine the impact of agency costs on firm performance of Vietnamese listed companies. Our sample includes 736 companies in Vietnam during the period om 2010 to 2015. We find that agency costs exert a negative impact on firm performance. Our results are robust to alternative econometric models, including an instrumental variables technique and a system generalized method of moment model. In addition, we show that a debt instrument can be a useful tool to reduce the negative impact of agency costs on firm performance.
Size Effect in Market-wide Liquidity Commonality: Evidence from the Indian Stock Market
Authors: Cheriyan Namitha K. , Lazar Daniel
Published: January 2020

Liquidity commonality and the co-movements in trading costs related to such commonality have remarkable implications in market microstructure. Analyzing and identifying such commonality will enable the investor and policy maker to discover evidence regarding the inventory risks and asymmetric information in uencing individual securities’ liquidity. Thus, this study aims at documenting the liquidity commonality and measuring its extent in the Indian stock market. Employing fourteen liquidity measures a ributed to the cost, quantity, time, and multidimensional aspects of liquidity, it empirically proves the existence of co-movements among market-wide liquidity and the individual securities’ liquidity. The study also shows the presence of a size effect in liquidity commonality in Indian stock market. It is found that the slope coefficient indicating the interface between market-wide liquidity and individual securities’ liquidity generally increases with size.
Foreign Ownership and Stock Return Volatility in Vietnam: the Destabilizing Role of Firm Size
Authors: To Anh Tho , Suzuki Yoshihisa , Vuong Bao Ngoc , Tran Quoc Tuan , Do Khoa
Published: January 2020

This study aims to examine the relevance of foreign ownership to stock return volatility in the Vietnam stock market over ten years (2008 - 2017). After applying the fixed effects regressions and the extended instrumental variable regressions with fixed effects, we find that foreign ownership decreases the volatility of stock returns. However, the stabilizing impact of foreign ownership on stock return volatility becomes weaker in large firms since the coeffcient of the interaction term between firm size and foreign ownership turns out to be significantly positive. The estimated results remain robust when we use the future one-year volatility, other than the current one, as an alternative measure of the dependent variable.
Economic Freedom, Globalization, and the Shadow Economy in the European Union Transition Economies: a Panel Cointegration Analysis
Authors: Bayar Yılmaz , Öztürk Ömer Faruk
Published: January 2020

The presence of the shadow economy differs considerably among the countries. Therefore, determination of factors behind the differences in the size of cross-country shadow economy becomes more of an issue for designing and implementing the right policies to combat the shadow economy. This study investigates the influence of economic freedom and globalization on the size of the shadow economy in the European Union transition economies employing panel data analysis for the period of 2000–2015. The empirical analysis indicates that economic freedom reduces the size of the shadow economy in the long term in the overall panel, but globalization also has a relatively smaller detractive effsect on the shadow economy in some countries.
Differences in the Receipt of Low-Value Services Between Publicly and Privately Insured Children
Authors: Chua Kao-Ping , Schwartz Aaron L. , Volerman Anna , Conti Rena M. , Huang Elbert S.
Published: January 2020

BACKGROUND:

Children frequently receive low-value services that do not improve health, but it is unknown whether the receipt of these services differs between publicly and privately insured children.

METHODS:

We analyzed 2013–2014 Medicaid Analytic eXtract and IBM MarketScan Commercial Claims and Encounters databases. Using 20 measures of low-value care (6 diagnostic testing measures, 5 imaging measures, and 9 prescription drug measures), we compared the proportion of publicly and privately insured children in 12 states who received low-value services at least once or twice in 2014; the proportion of publicly and privately insured children who received low-value diagnostic tests, imaging tests, and prescription drugs at least once; and the proportion of publicly and privately insured children eligible for each measure who received the service at least once.

RESULTS:

Among 6 951 556 publicly insured children and 1 647 946 privately insured children, respectively, 11.0% and 8.9% received low-value services at least once, 3.9% and 2.8% received low-value services at least twice, 3.2% and 3.8% received low-value diagnostic tests at least once, 0.4% and 0.4% received low-value imaging tests at least once, and 8.4% and 5.5% received low-value prescription drug services at least once. Differences in the proportion of eligible children receiving each service were typically small (median difference among 20 measures, public minus private: +0.3 percentage points).

CONCLUSIONS:

In 2014, 1 in 9 publicly insured and 1 in 11 privately insured children received low-value services. Differences between populations were modest overall, suggesting that wasteful care is not highly associated with payer type. Efforts to reduce this care should target all populations regardless of payer mix.
Application of Mind Map-based abstracting technique in pedagogical strategy for ESP teaching/learning
Authors: Choporova Ekaterina
Published: January 2020

The work presents some theoretical and practical results of the abstracting practice carried out by the teachers and cadets of Voronezh Institute of the Ministry of Interior of Russia. The sources used in the experiment were of British and American origin, equally authentic, and were mainly of engineering content because of the cadets’ speciality. The main purpose of the experiment was focused on the primary source adequate abstract making as a product of a keen understanding of social and professional aspects, views, and anticipations of English-speaking nations. The authors analyzed a number of current approaches towards abstract making procedures and offered an original system of the education strategy by means of Mind Map building technique.
Elaborating on Internet addiction and cyberchondria – relationships, direct and mediated effects
Authors: Ivanova Eliza , Karabeliova Sonya
Published: January 2020

The present paper focuses on the effects of personality traits on the levels of Internet addiction and cyberchondria and their consequent effects on well-being. For the purposes of the research, mediation analyses were carried out, clarifying the infl uence of personality traits on well-being mediated by Internet addiction, cyberchondria and anxiety aroused by online health information seeking. It was established that Neuroticism leads to decreased well-being through the mediating infl uence of health anxiety, escalation and persistence of health concerns. Health anxiety is a mediator in the relationship between Openness to Experience and well-being. It was established that low levels of Agreeableness and Conscientiousness, and high levels of Openness, and Neuroticism, infl uence Internet addiction, which in turn leads to decreased well-being. Furthermore, we established the mediated infl uence of Internet addiction on the tendency for cyberchondria and health anxiety through using the Internet for health information and judgment biases.
Early childhood identity: ethnicity and acculturation
Authors: Dan Maria
Published: January 2020

How are concepts such as ethnic identity, acculturation and cultural orientation being perceived by a child? What is the process of identity construction in early preschool age? How is children’s wellbeing affected by parents’ desire to expose them to a certain culture, other than the one the children were born into? How natural is learning a foreign language for children, given a multiethnic space characterized by adversity and disparities such as “them”- -“us”? And what are the potential outcomes of the phenomena in question? These are a few questions that the current study refl ectively followed up upon by using a qualitative research design and data triangulation in order to increase its validity. The SDQ Questionnaire used to study the children’s wellbeing, the semi-structured “in-depth” interviews conducted on the main early preschool identity builders in the Cristian community and the participative observation indicated the children were proud to be part of the German department group. They did not undergo a brutal process of affi liation to the Saxon ethnicity due to the educators’ various compromises, and their wellbeing didn’t seem to be affected at the SDQ administration stage. However, learning German proved to be a diffi cult process and the two potential outcomes included hitting the language barrier or resuming adaptation to the native ethnic code. This study highlights the impact of the cultural code on the early identity foundation.
The Functional Role of Music in Communicating Death through/in YouTube Videos
Authors: Pentaris Panagiotis , Yerosimou Maria
Published: January 2020

Since the establishment of thanatology, the science of death, in the early 20th century, death has not only been considered a controversial subject, but it has also been regarded as a taboo topic. Various ways of communicating death have developed over the last few decades. With the advent of different mass and social media and their increasing impact on everyday life in the 21st century, death can now be communicated via a number of media platforms, such as television, radio, and online videos. This type of communication is underpinned by a series of dimensions, in particular music, that shape the conveyed message. Music has been extensively used in the dissemination of information in the wider media outlet. It is widely seen as a means of evoking emotions and of facilitating the process of assimilating information that is communicated via media. This paper seeks to discuss the functional role of music in communicating death in online video platforms. In particular, the example of the YouTube platform is used to identify the links between death, music and video platforms. This paper is part of a large-scale study on the functional role of music in communicating death through YouTube videos. It is suggested that music may serve as a link between media and death. The conclusions that are drawn in this paper are supported by the authors’ current and ongoing study and critical analysis of the deployment of music in the communication of death.
The Slovenian Art History Textbook in Comparison to Polish Textbooks: Authorship and Content, Didactic Structure and Publishing Circumstances
Authors: Dolšina Marjana
Published: January 2020

The paper analyses two concepts of art history textbooks for secondary schools. It discusses their role in the learning and teaching process of art history and related school subjects within the formal educational programmes in Slovenia and their didactic structure. The comparison between one Slovenian and two Polish textbooks might contribute to better understanding of the present situation regarding art history textbook production in Slovenia, which is a result of several factors: the historical continuity of textbook writing and research in textbook didactics, the current school policy and fi nancial competition on the textbook market. Its intention is also to clarify the idea of didactic transformation of the art history contents from the challenging scientifi c texts to a form suitable for secondary school students who are textbooks’ main target audience.