bluuebunny/crossref_metadata_2025 huggingface dataset:
Preeclampsia: Advances in understanding, management and prevention
Authors: Cotrina Celiz Eresvita , Villanueva Julcamoro Maritza Mercedes , Vivanco Hilario Sofía Dora
Published: December 2024

Introduction: Preeclampsia is one of the most serious obstetric complications, associated with high maternal and fetal morbidity and mortality. It affects between 2% and 8% of pregnancies, representing a significant threat to women's health. Its management requires a multidisciplinary approach, given its multifactorial origin.Development: The pathophysiology of preeclampsia involves alterations in placental remodeling and endothelial dysfunction, leading to hypertension and proteinuria. These conditions reflect hemodynamic imbalance and involve vital organs. Early identification by constant monitoring of blood pressure and proteinuria is crucial to avoid serious complications. Although labor is the definitive treatment, the decision to induce labor should be made with caution, especially in severe cases. Pharmacological therapies, such as antihypertensives and magnesium sulfate, are essential for acute management, but the approach should be comprehensive, considering the individual needs of each patient. The role of nursing is fundamental not only in the clinical setting, but also in the emotional support and empowerment of women, following models of care such as those proposed by Orem and Swanson.Conclusions: Despite advances in the understanding and treatment of preeclampsia, it remains a significant global public health challenge. Prevention through evidence-based interventions and improved access to antenatal care are essential to reduce its impact. A multidisciplinary approach and commitment to research are key to improving maternal and fetal outcomes
Systematic analysis of recent scientific literature on edentulism using the PRISMA 2020 methodology
Authors: Cargua Ríos José Napoleón
Published: December 2024

Edentulism is an oral health condition that significantly impacts quality of life, masticatory function, and aesthetics, representing a major challenge in clinical practice and global public health. The aim of this study was to analyze recent scientific literature on edentulism published between 2020 and 2025 to identify trends, associated factors, and therapeutic approaches, in order to contribute to updated knowledge and the improvement of its clinical and preventive management. A systematic review was conducted following PRISMA 2020 guidelines, selecting 3,657 relevant studies from the PubMed database, from which 12 articles meeting strict inclusion criteria were included. The results highlighted that psychological and patient factors are crucial in adapting to complete dentures; digital technologies, such as computer-assisted surgery and 3D printing, significantly enhance precision and functionality in oral rehabilitation; denture adhesives and space registration methods contribute to improved stability and masticatory performance; and epidemiological projections warn of an increase in edentulism and severe periodontitis by 2050. It is concluded that managing edentulism requires a multidisciplinary approach that integrates advanced technological interventions, psychological strategies, and public health policies focused on prevention. This study provides a comprehensive foundation to improve clinical care and guide future research in the field of edentulism
Use of analgesics to control oral pain
Authors: Toala Tapia Adrián Isaac , Jiménez Malla Gabriela Alejandra , Torres Quiñonez Paulette Andreina , Buitrón Recalde Marianela del Rocío
Published: December 2024

In orthodontics, the number of patients treated for pain problems associated with treatments is significant, which is a concern for patients and professionals in this branch. Analgesics have been widely used during orthodontic treatment with the aim of controlling pain based on different situations. The study carried out a review of the research developed on the subject, analyzing the different types of analgesics used, the mechanisms of action and their effectiveness, among other elements. From the extensive bibliography found through the use of Google Scholar and Pubmed, 11 were selected that met the requirements for the objective of the review and due to the level of update on the topic. After completing the study, it was concluded that paracetamol is the most suggested analgesic in the first instance due to its action on the central nervous system and less damage
Colorectal Cancer Screening in Saudi Arabia: Sociodemographic Influences and Beliefs
Authors: Mahmoud Saleh Ahmad
Published: December 2024

Introduction: Colorectal cancer (CRC), the most common cancer among Saudi men, is a significant health concern. This study explored how beliefs and sociodemographic factors influenced screening behaviors in individuals aged 45–74 in Al-Kharj. Methods: This descriptive cross-sectional study, conducted in Al-Kharj in May and June 2024, used a web-based survey to assess cancer awareness and prevention beliefs among men aged 45–74. A purposeful sampling strategy with targeted advertising ensured demographic representation. Data were analyzed using chi-square tests and logistic regression to examine the influence of sociodemographic factors on CRC screening behaviors. Results: Of the 70 participants, 70% had previously undergone colorectal cancer (CRC) screening, with most expressing positive views about cancer outcomes and care. Those who had never been screened were more likely to believe that screening is only necessary when symptoms are present (X² = 16.045, p < 0.01), view screening as having a high risk of leading to unnecessary surgery (X² = 12.934, p = 0.024), and feel deterred by concerns about potential findings (X² = 14.27, p = 0.014). Regression analysis indicated that men, except those aged 45–54, were significantly more likely to have undergone screening than women (OR = 3.76, 95% CI = 1.104–12.801). No significant associations were found with other sociodemographic variables. Conclusion: Cancer screening behavior is influenced by beliefs about cancer screening, but the impact is minimal, suggesting a broad reach across various socioeconomic backgrounds
Transforming abdominal reconstruction-impact of artificial intelligence algorithms and advanced technologies on the efficiency of vascularized flaps and postoperative functional restoration: a systematic review
Authors: Chafla Romero Luisa Paulina , Navarro Hernandez Claudia Janeth , Andrade Veloz Bryan Andrés , Maldonado Lopez Jorge Eduardo , Sánchez Romero Evelyn Michelle , Cuello Carranza Adlay Jambick , Pérez Pérez Lisbet Yuliana , Franco Vaca Ana José
Published: December 2024

Abdominal Reconstruction shows the progress created by artificial intelligence and machine learning AI & ML, especially those involving vascularized flaps. Therefore, this systematic review seeks to find out how incorporating AI can transform surgical accuracy, minimize post-surgical complications, as well as improve the recovery process. AI is already being used for planning surgery forecasting failure of flaps as well and minimizing SSI. Machine learning models like neural networks demonstrate impressive accuracy in identifying high-risk patients such as those with obesity, chemotherapy exposure, or large fascial defects. Real-time data analytics, remote monitoring through AI and ML have improved the decision-making process and led to efficient surgeries and better functional outcomes by reducing surgical failure and post-operative complications. Integrating AI into complex surgical environments requires carefully balancing machine recommendations and human expertise yet ethical concerns surrounding data transparency, bias, and patient privacy and these concerns need critical consideration and must be addressed.  We conducted this review systematically to evaluate existing studies, revealing that while AI is promising to improve surgical outcomes, its real-world applications are still in their infancy, and we will evaluate how AI has transformed abdominal reconstruction surgical procedures, plastic surgeries, such as breast reconstruction or abdominal wall hernias, or other oncological resections
Using Adobe Creative Cloud to create multimedia content in higher education institutions
Authors: Snihur Olena , Maleyka Jamshid Alizada , Golubytskyi Sergii , Hrechko Andrii , Prockopets Kostyantyn
Published: December 2024

Introduction: Digital content is a powerful tool for enhancing students’ interest in the learning process. The aim of the work is to determine the effectiveness of using Adobe Creative Cloud to create multimedia content in higher education institutions (HEIs).
Methods: He research employed the methods of observation, deduction, Thurstone scale, calculations of priority coefficient, knowledge coefficient and Student’s coefficient.
Results: It was established that during training, Adobe Creative Cloud can be used to conduct theoretical and practical classes and develop students’ creative skills. It was established that charts ( 1.2) and illustrations ( 1.1) have the greatest importance in the created content for students’ perception. Textual information is less important for the perception of educational materials ( 0.73). The students were found to perceive learning using Adobe Creative Cloud at a high level, which is associated with not overloading students with unnecessary materials and ensuring visual perception. The authors determined that students of Group 1 (Software Engineering) and Group 2 (History) achieved high academic results — ( =1.01), ( =1.0), respectively.
Conclusions: The practical significance of the work is the possibility of expanding students’ approaches to building professional competence on the basis of content created using Adobe Creative Cloud
The Influence Of Understanding Village Fund Accounting And Community Participation In Fund Management Village With The Principle Of Tri Pantangan As A Variable Moderation
Authors: Ayem Sri , Anggita Saskia
Published: December 2024

The purpose of this study was to determine the effect of accounting understanding and community participation on village fund management with the principle of tri pantang as a moderator variable in villages in Tumbangtiti District, Ketapang Regency. This research method uses primary data, and the data collection method uses a questionnaire technique. The population in this study includes all village officials in the Tumbangtiti District, Ketapang Regency, consisting of the Village Head, Village Secretary, Treasurer, and Finance Officer. The sampling technique used is non-probability obtained through questionnaire distribution, with a total of 64 respondents. The results of this study indicate that accounting understanding has a positive effect on village fund management, community participation has a positive effect on village fund management, tri pantang cannot moderate the effect of accounting understanding on village fund management, and tri pantang moderates the positive effect of community participation on village fund management.
A bibliometric analysis of 10 years of publications on L-citrulline
Authors: Ghozali Dhoni A. , Doewes Muchsin , Soetrisno Soetrisno , Indarto Dono , Ilyas Muhana F.
Published: December 2024

Context: L-citrulline is a non-essential amino acid primarily sourced from watermelon (Citrullus vulgaris). Many studies on L-citrulline have been conducted in the past 10 years. However, no bibliometric analyses have been performed.

Aims: To establish bibliometric analysis as a comprehensive review of L-citrulline literature.

Methods: Articles on L-citrulline published between 2013 and 2022 were retrieved from the Scopus database. The data was then analyzed for trends and quantity descriptions of authors, countries, and journals. The Vosviewer software was used to visualize the networks of keywords.

Results: The analysis was conducted on September 9, 2022. From 2013 to 2022, 563 papers were retrieved in total. The number of L-citrulline publications had increased dramatically. The United States appeared to be the leading nation, providing the greatest number of publications and involving the world's leading writers and organizations. L-citrulline research has primarily concentrated on nitric oxide synthase, ergogenic aid, and exercise performance. Based on the analysis of keywords with the less frequent occurrence, this study also identified possible themes for future investigation, especially in topics such as ‘body composition’, ‘diabetic nephropathy’, ‘exercise capacity’, ‘human recombinant arginase I’, ‘lactate’, ‘lactation’, ‘microcirculation’, ‘reactive oxygen species’, ‘skeletal muscle’, ‘watermelon rind’ and ‘watermelon juice’.

Conclusion: Publications on L-citrulline are essential, but the amount is still insufficient. Further research is required.
The effects of acupuncture and methylprednisolone on cortisol levels in mice with lupus nephritis model
Authors: Suparyanti Endang Listyaningsih , Purwanto Bambang , Wasita Brian , Handayani Selfi
Published: December 2024

Context: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the involvement of multisystemic and diverse autoantibodies in target cell components. One clinical manifestation of SLE is lupus nephritis. Acupuncture is one therapeutic method based on the philosophy of self-healing potential, the ability of the body to heal itself.

Aims: To measure the therapeutic effects of acupuncture points of Mingmen (GV4) and Zusanli (ST36) along with methylprednisolone in mice with lupus nephritis model by comparing cortisol levels.

Methods: This study was an experimental study on mice (Mus musculus) modeled with lupus nephritis using post-test only on a control group design. The subjects were assigned into four groups, each with seven mice, consisting of the control group (CN), the negative control group administered with pristane (C(-)), the first test group treated with both pristane and methylprednisolone (P1), and second test group administered with pristane and acupuncture in Mingmen and Zusanli points. The significance level was determined to be less than 0.05.

Results: A statistically significant difference occurred between groups in this investigation, as demonstrated by a one-way ANOVA test (F=11.710, p=0.000). A Tukey post hoc test showed that the mice treated with pristane (C(-)) displayed higher cortisol than the other groups: P1 group (p=0.000), P2 group (p=0.025), and the control group (CN group) (p=0.000). However, no significant difference was displayed in the control group (CN) with P1 (p=0.888), the control group (CN) with P2 (0.112), and between the P1 and P2 groups (p=0.374).

Conclusion: Significantly, there was a difference between the group of mice given pristane (C(-)) and the one treated with pristane and methylprednisolone (P1), and the pristane and acupuncture (P2) group, with the control group (CN). Acupuncture had an equal effect on cortisol levels with methylprednisolone in mice models of lupus nephritis.
The effect of SPIRIT program on the anxiety of elderly in nursing homes: A pilot study
Authors: Cahyanto Erindra Budi , Subijanto Achmad Arman , Kristiyanto Agus , Sumardiyono Sumardiyono
Published: December 2024

Context: It is a pilot study to test the feasibility and the effect of a new program, namely SPIRIT, which is a comprehensive physical and mental activity to enhance the quality of life of elderly people in nursing homes.

Aims: To determine the effect of a comprehensive program on reducing anxiety.

Methods: The design was a quasi-experiment one group pre-test-post-test. A comprehensive program consisted of elderly gymnastics, pedaling a stationary bicycle, walking, muscle strength training, flexibility, balance, breathing relaxation, and gratitude, which were carried out three times a week for four weeks. Seven elderly who were able to do activities independently and met the criteria were willing to become participants. The results measured included the presence or absence of side effects, mean attendance, dropout rates, and anxiety scores.

Results: No unexpected events occurred during the intervention. Average attendance was 86%. The mean anxiety score at baseline was 14 ±5.13 and 11 ± 3.55 at the follow-up. There was a significant decrease in anxiety with p<0.01. SPIRIT program effectively was able to reduce anxiety and deserved to be used for further research.

Conclusion: The SPIRIT program effectively was able to reduce anxiety and deserved to be used for further research.
Correlation between MDS UPDRS III with depression, anxiety, and fatigue symptoms in Parkinson’s disease
Authors: Hutabarat Ervina A.J. , Suroto Suroto , Mirawati Diah K. , Subandi Subandi , Danuaji Rivan , Budianto Pepi , Hambarsari Yetty , Hamidi Baarid L. , Prabaningtyas Hanindia R. , Ristinawati Ira , Tejomukti Teddy , , Tedjo Andi A. , Putri Ardisa P. , Putra Andry N.
Published: December 2024

Context: One of the most prevalent neurodegenerative disorders affecting persons between the ages of 40 and 70 is Parkinson's disease. Non-motor Parkinson’s symptoms are divided into sleep symptoms, dysautonomia symptoms, neuropsychiatric symptoms, and sensory symptoms. Fatigue, depression, and anxiety are non-motor symptoms of Parkinson's that significantly worsen the quality of life.

Aims: To evaluate the effects of motor function scores using The Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) PART III values on fatigue, depression, and anxiety in Parkinson's patients.

Methods: This was an observational quantitative analytic study with a cross-sectional approach. There were 30 respondents in this research. All of them were Parkinson's patients who were being examined and assessed with MDS–UPDRS PART III in the Neurology department of RSUD Dr. Moewardi from July 2021 to September 2022. Fatigue Severity Scale, Hamilton Depression Scale, and Hamilton Anxiety Scale were used to score patients' fatigue, depression, and anxiety levels.

Results: MDS–UPDRS PART III scores and Parkinson patients' depression, fatigue, and anxiety levels were compared with the Spearman correlation test. A statistically significant result was obtained between the scores with depression (p<0.05; 0.862), anxiety (p<0.05; 0.584), and fatigue (p<0.05; 0.898).

Conclusion: The severity of MDS-UPDRS PART III and the signs of fatigue, anxiety, and depression were strongly and positively correlated. This study showed that the motoric symptoms score value increased with the likelihood of patients experiencing depression, anxiety, and tiredness.
Application of mid-upper arm muscle circumference measurement in medical nutritional therapy for chronic kidney disease patients experiencing routine hemodialysis and experiencing malnutrition: A case report
Authors: Alam Muningtya P. , Andayani Diyah E. , Alfara Lady D.
Published: December 2024

Context: Chronic kidney disease (CKD) patients on routine hemodialysis are often diagnosed with protein-energy wasting (PEW). Medical nutritional therapy can be used to prevent PEW and improve the quality of life. Mid-upper arm muscle circumference is a reliable index to describe total body protein and muscle mass. In this study, four CKD patients and experiencing hemodialysis for about 6 weeks were monitored.

Aims: To examine the benefit of medical nutritional therapy on mid-upper arm muscle circumference measurements in malnourished CKD patients experiencing routine hemodialysis.

Methods: The observational method was used.

Results: Two patients had a good appetite with their energy and protein intake exceeding 35 kcal/ideal BW and 1.5 g/ideal BW, respectively, during the initial assessment. The other two patients had respective values ranging from 20-25 kcal/ideal BW and 0.5-0.8 g/ideal BW. All patients had low upper arm muscle circumference indicating potential muscle depletion. During monitoring, the energy and protein intake increased in three patients, but decrease in protein intake but still met the target of 1.1-1.4 g/ideal BW/day. In line with the reference, all patients had MUAMC measurements below the 50th percentile, indicating malnutrition and decreased muscle mass. Two patients were diagnosed with PEW, while the remaining were found to be at risk.

Conclusion: The assessment of malnutrition risk and implementation of adequate nutritional therapy in CKD patients experiencing routine hemodialysis should be prioritized to prevent the progression of PEW.
Effect of kebar grass extract (Biophytum petersianum Klotszch) on luteinizing and follicle-stimulating hormone levels in rat model polycystic ovarium syndrome
Authors: Putri Noviyati Rahardjo , Hidayat Syarief Thaufik , Widyawati Melyana Nurul , Suwondo Ari , Sudirman Sudirman , Ramadhian Aida Amalia Nur
Published: December 2024

Context: The major cause of infertility is polycystic ovary syndrome (PCOS). PCOS symptom is folliculogenesis disorder, increasing LH:FSH levels (3:1), and insulin resistence. As the fertilizer herb in Indonesia, kebar grass (Biophytum petersianum Klotzsch) has two types of protein with a molecular weight as same as pregnant mare serum gonadotrophin hormone (PMSG), which has follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity. It contains antioxidants, vitamin A, vitamin E, saponins, and amino acids. Unfortunately, it has not been conducted for PCOS.

Aims: To determine the effect of B. petersianum extract on LH and FSH levels in a PCOS rat model.

Methods: This study was a posttest only with a control group design. The sample consisted of five groups: C1 (healthy model), C2 (PCOS model), D1, D2, and D3 (dose 31.5, 63, and 94.5 mg/kg BW of kebab grass extract).

Results: B. petersianum extract reduced LH levels and increased FSH levels in blood serum measurement with p values of 0.007 and 0.013. The optimal dose was dose 2 (63 mg/kg bw). The glycoprotein content in B. Petersianum, which showed the same atomic weight as the PMSG, was thought to be a stimulator growth factor of follicles. The antioxidant content was also thought to inhibit prostaglandin precursors. It could restore the production of gonadotropin-releasing hormone to the normal hypothalamic-pituitary-ovarian (HPO).

Conclusion: B. petersianum extract can improve reproductive performance in the PCOS rat model. This research can be a reference for further research in reproductive disorders and the development of the clinical trial stage of traditional medical plants.ating TGF-β expression and promoting the formation of reparative dentin.
Moringa oleifera extract in decreasing disease activity for patients with rheumatoid arthritis
Authors: Prabowo Nurhasan Agung , Nurudhin Arief , Werdiningsih Yulyani , Putranto Wachid , Kusumo Tri , Hartono Hartono , Putri Desy Puspa
Published: December 2024

Context: Rheumatoid arthritis (RA) is a chronic and progressive disease that destroys the human joints. Only a few patients have remission, and the currently available drug has side effects. Moringa oleifera has anti-inflammation, immunomodulation, and immunosuppressant properties, which can be a candidate for a potential treatment for RA patients.

Aims: To determine how M. oliefera extract affects RA patients' DAS28-CRP scores.

Methods: Using the randomized controlled trial, the size of the samples reached 30 participants. Research subjects were categorized into two groups: the treatment group (n = 15, M. oleifera 1000 mg bi in day) and the control group (n = 15, placebo). DAS28-CRP levels of disease activity were measured both during pre- and post-treatment.

Results: The results showed the improvement of DAS28-hsCRP pre- and post-M. oleifera leaf extract (MO) administration within the M. oleifera group (p=0.001). After therapy, the scores of DAS28-CRP differed between the control and MO groups (p=0.001).

Conclusion: M. oleifera leaf extract administration reduced DAS28-hsCRP scores in RA patients.
Effect of Solanum betaceum Cav. extract on malondialdehyde, testosterone, and Sertoli cells in lead acetate-induced mice
Authors: Wahidah Nurul Jannatul , Zakiah Abadiyah , Riris A.A. Cyntia , Wirenviona Rima , Susanti Nurul Fatimah , Novika Revi Gama Hatta , I’tishom Reny , Khaerunnisa Siti
Published: December 2024

Context: Lead exposure has been scientifically associated with male infertility with an unclear cause. According to studies, lead exposure has a significant association with infertility in both women and men. Lead that is ingested or inhaled and enters the body can increase reactive oxygen species (ROS), which affect sperm quality.

Aims: To evaluate the effects of Solanum betaceum extract on malondialdehyde (MDA), testosterone, and Sertoli cells in lead acetate-induced mice.

Methods: 40 male mice weighing 25–30 grams and aged 12–16 weeks were used in this study. In addition, this study is an experimental study with a randomly allocated posttest-only control group design. For 35 days, mice were randomly divided into five groups: K- (the negative control group, distilled water), K+ (the positive control group, lead administration only), P1 (administered with 100 mg/kg BW S. betaceum extract), P2 (administered with 200 mg/kg BW S. betaceum extract), P3 (administered with 400 mg/kg BW S. betaceum extract). On day 36, mice were sacrificed, and the testicular tissues were taken. These tissues were then examined for their MDA levels through an ELISA test and for the number of their Sertoli cells through a histological study. Simultaneously, 3 mL of blood were drawn from the hearts of mice to be analyzed for the testosterone level by an ELISA test.

Results: This study showed that although S. betaceum could not significantly affect MDA level (p>0.05), it could significantly affect testosterone level and Sertoli cells.

Conclusion: The administration of S. betaceum was able to protect the Sertoli cells and testosterone in mice induced with lead acetate.
Bibliometric analysis of research in Moringa oleifera Lam. and atherosclerosis
Authors: Rahayu Rachmi Fauziah , Prayitno Adi , Purwanto Bambang , Widiastuti Widiastuti , Nurwati Ida , Poncorini Eti , Soetrisno Soetrisno
Published: December 2024

Context: Moringa oleifera is a plant with many benefits, and its polyphenols have potential in the medication system due to their hypoglycemic activity. One of its functions is to prevent atherosclerosis by inhibiting the production of ROS.

Aims: To analyze the scope of the effect of Moringa oleifera on atherosclerosis research using a bibliometric review.

Methods: This investigation searched the Scopus electronic database for relevant articles on the effect of M. oleifera on atherosclerosis research. Basic bibliographic data were obtained through database analysis and citation reporting functions. This study exported the full bibliographic data to VOSviewer for further analysis. A visualization map was then created to reiterate the author’s keywords and terms mentioned in the title and abstract of the publication.

Results: The data in this research included research trends and future research opportunities regarding M. oleifera on atherosclerosis. Around 1051 metadata articles on M. oleifera in relation to atherosclerosis were extracted from Scopus database. These articles were published between 2012 to 2022. The literature accepted contributions from all over the world, with the most productive countries being India, China, and Nigeria. Some of the most frequently cited themes, shown by keywords such as oxidative stress, M. oleifera, and diabetes, indicated that there had been numerous research progressing on these themes.

Conclusion: In relation to research on M. oleifera and atherosclerosis, there are still plenty of research topics that have not been widely covered, mainly those related to streptozotocin, dyslipidemia, and apoptosis, among others., which might be an opportunity for further research scope.
Conservative management of grade III penile injury using topical mupirocin: A case report
Authors: Laksono Rizki Abri , Nurizzan M. Ghilman
Published: December 2024

Context: ns is infrequent, accounting for 0.2% to 8% of all reported cases of pediatric trauma. While the majority of literature emphasizes surgical intervention for severe (grade III) penile injuries, there is limited discussion on conservative management approaches. This study explores the efficacy of topical mupirocin in the conservative management of grade III penile injuries. Mupirocin, a topical antibiotic, inhibits bacterial protein synthesis and thereby reduces the risk of wound infection and promotes healing.

Aims: To evaluate the outcomes of using topical mupirocin in the conservative management of grade III penile injuries.

Methods: A case involving a 3-year-old male who sustained a penile injury following a fall was reviewed. Physical examination revealed erythema, swelling, and a hematoma of the glans penis. The patient was diagnosed with grade III penile injury, then underwent penile exploration and circumcision procedure, with subsequent conservative treatment involving topical mupirocin.

Results: The penile laceration, hematoma, and edema were minimal. The absence of additional injuries in the urogenital system allowed for a conservative treatment approach with mupirocin. The patient was discharged after three days, and a follow-up one week later showed substantial wound healing without complications.

Conclusion: This case suggests that, contrary to some recommendations for surgical management of grade III penile injuries, conservative treatment with topical mupirocin can be effective and warrant further consideration.
Interprofessional relation models in type 2 diabetes mellitus: A systematic review
Authors: Ma’rufah Siti , Satibi Satibi , Yasin Nanang M. , Kristina Susi A.
Published: December 2024

Context: Diabetes mellitus is one of the biggest non-communicable disease problems worldwide and 90% of diabetes cases are type 2 diabetes mellitus. This chronic disease requires continuous monitoring by the interprofessional relations team to prevent the progression of more severe complications and improve the quality of life.

Aims: To determine the models of interprofessional relations with patients with type 2 diabetes mellitus in the community and hospital.

Methods: A systematic literature search was conducted in three online databases (Google Scholar, Science Direct, and Scopus). From 22690 returned studies, 12 met the predefined inclusion criteria. The quality of each paper was evaluated using the evidence-based practice tools provided by Johns Hopkins. A PRISMA flow chart documented the search, exclusion, and inclusion criteria study.

Results: The majority of approaches employed comprised a mixture of training, daily huddles, coordinated care plans, joint patient visits, follow-up phone calls with patients, medication reviews, educational initiatives, diabetic group sessions led by students, participation in scientific conferences, and utilization of the care networks. Positive advancements were observed in HbA1c levels, blood pressure management, body mass index, low-density lipoprotein cholesterol, total cholesterol, enhanced teamwork, data security, time efficiency, and automated processes.

Conclusion: Interprofessional relations with one or a combination of interventions positively affect clinical and non-clinical parameters in the community and hospital.
Trends and visualization in honey and diabetes mellitus study from 1953 to 2022
Authors: Munawaroh Siti , Wiyono Nanang , Hastami Yunia
Published: December 2024

Context: Diabetes mellitus (DM) is a globally emerging health issue, ranking among the top five contributors to mortality and morbidity worldwide. Numerous studies have diligently identified efficacious treatments for DM, and honey is a natural ingredient of interest among the alternatives explored in the field of anti-diabetic therapy.

Aims: To determine study trends related to honey and DM.

Methods: Bibliometric analysis used the Scopus database, and VOSviewer software was used to analyze countries, journals, and keywords. The study carried out on September 28, 2022, found a total of 586 documents in the period 1953 to 2022. The search used the keywords honey AND diabet* with restrictions on the source type of journals.

Results: The results showed that publications on honey and DM had grown significantly in the last ten years. United States was a leading country in honey and DM study, accounting for the most significant number of publications worldwide, with authors and research institutes. Nutrient Journal stood out as a major periodical and keyword analysis showed that studies on honey and DM were focused on themes related to humans, glucose blood levels, and wound healing.

Conclusion: Bibliometric analysis provided relevant information on the main themes studied on honey and DM.
The effectiveness of psychocurative on the anxiety scale and the levels of cortisol, serotonin, and prolactin in postpartum women
Authors: Soetrisno Soetrisno , Novika Revi Gama Hatta , Cahyanto Erindra Budi , Nurinasari Hafi , Arifa Haris Nur Ashfi , Sari Atriany Nilam , Maulida Luluk Fajria , Ilyas Muhana Fawwazy
Published: December 2024

Context: The anxiety experienced by mothers during postpartum may have a negative impact on the emotional, psychological, and social development of newborns. Moreover, a psychological intervention known as psychocurative aims to maintain a Person’s mental state, encompassing their cognitive, spiritual, social, and physical well-being. However, the impact of the intervention on hormonal changes during postpartum remains unknown. Therefore, this study aimed to analyze the impact of psychocurative intervention on levels of cortisol, serotonin, and prolactin, as well as the anxiety scale.

Aims: To analyze the impact of psychocurative intervention on levels of cortisol, serotonin, and prolactin, as well as the anxiety scale.

Methods: This study was quasi-experimental research and employed one-group pre-test and post-test designs. Moreover, the research subjects were twenty postpartum women at Sibela Public Health Center in Surakarta. Additionally, the Wilcoxon test was employed to analyze all variables. Furthermore, the intervention was given to the research subjects once a week in the mother’s class provided by the Sibela Public Health Center and twice at their homes. In addition, the DASS-21 was employed to measure the anxiety scale, while the ELISA test was employed to measure levels of cortisol, serotonin, and prolactin. All variables were evaluated before and after the intervention to see the significant impact.

Results: The difference in the mean result of levels of cortisol, serotonin, and prolactin, as well as the anxiety before and after psychocurative intervention, was significant (p<0.05).

Conclusion: Psychocurative has been demonstrated to increase serotonin and prolactin expression while decreasing cortisol levels and the anxiety scale.
X Ray Based Laboratory Testing Methodology for Panel Products against Termite Resistance
Authors: Solanki Riya Tudu
Published: December 2024

A host of new eco- friendly preservatives and treatments for protection of panel products are being developed. Engineered wood products require extra caution while testing with termites, due to high moisture conditions during field tests, a composite panel may subject to delamination making it difficult for a proper rating and determination of damage due to termite activity. This work focuses on development of a laboratory testing method for plywood and blockboard resistance against termite species Heterotermes indicola and Coptotermes heimi. The termite species preferability test was done in order to find out the most palletable wood species. Pinus sp and Mangifera sp. were found to be the most palletable wood species and were taken as control.   Determination of maximum vigorous activity of both the termite species were done by monitoring wood consumption and survival, and it was found that Heterotermes indicola showed highest survival at population density of 0.004 g/ml, whereas Coptotermes heimi showed highest survival at population density of 0.0008 g/ml. A non-destructive and quantitative approach of X-Ray analysis was adopted for result evaluation for more quantifiable result than traditional visual observation. Based upon the results obtained, a termite testing methodology was developed for wood based panel products such as plywood and block board.
Effect of Different Growing Media on Germination and Seedling Growth of Wild Almond (Sterculia foetida L.)
Authors: Gamit Asha. P. , Patel Mehfuza. M. , Parmar Mukesh R. , Desai Bimal. S.
Published: December 2024

Sterculia foetida L. is a tropical endangered tree species belongs to the family Sterculiaceae which is also called as Java-Olive or wild almond tree. Looking into the importance of S. foetida L. the present experiment entitled effect of different growing media on germination and seedling growth of wild almond (Sterculia foetida L.) was conducted. The experiment was laid out in Completely Randomized Design (CRD) with 6 treatments and 3 repetitions in which 10 seedlings per treatment per repetition were taken for study. From the result of experiment and foregoing discussion, the following conclusion can be drawn: Among all the growing media, soil:sand:vermicompost (2:1:1) found the most effective for seed germination, seedling growth and biomass parameters in Wild almond (S. foetida L.).
The Family Response and Impact of the "Double Reduction" Education Reform in Chinese Compulsory Education
Authors: Gao Xianwei
Published: December 2024

"Reducing the burden" has always been a hot topic in the reform of basic education, and it has been also one of the issues that parents focus on. The "Double Reduction" policy clearly requires that schools, teachers, and parents must reduce the homework burden and extracurricular training burden of students in the compulsory education stage, and shall not assign homework that exceeds the level of the national curriculum standards; must not assign homework to parents or assign homework in disguise; shall not require parents to check and correct homework; teachers shall not participate in paid tutoring outside of school, etc. Although the "Double Reduction" policy is related to the transformation of family education in every family, there is still a lack of research on the family reaction and impact of the "Double Reduction" in education in Henan Province. This study conducted a survey on the implementation status, satisfaction, influencing factors and outstanding problems of students in two districts, two cities, and two counties of Xuchang City, Henan Province using SPSS 26.0 for quantitative questionnaire analysis (n=450) and NVivo 12 for qualitative interview text transcription research.
This study found the following four main aspects: 1) The degree of understanding of the "Double Reduction" policy among family members in Xuchang, Henan Province; 2) The reaction of family members in Xuchang, Henan Province to the "Double Reduction" policy and the focus on investigating the basic information of family members in Xuchang, including gender, parental titles, age, family income, and parents' and children's educational backgrounds; 3) The impact of the "Double Reduction" policy on family members in Xuchang, Henan Province, including changes in children's grades, changes in parenting styles, parent-child companionship and communication, investment in hobbies, investment in subject education, and leisure time arrangements; 4) Changes in parenting styles in Xuchang, Henan Province under the "Double Reduction" policy.
This study is conducive to understanding the inner voice of contemporary students, providing a practical basis for improving students' all-round development and releasing social vitality, improving the quality of education, strengthening the role of school education as the main battlefield, ensuring that more families reduce economic pressure, and reducing the homework burden and off-campus training burden of students in compulsory education.
Green Synthesis of Silver Nanoparticles from Leaf and Flower Extracts of R. indica and C. roseus
Authors: Rao Sonali , Sahai Pragati , Kumar Vinay , Ahmad Nabeel , Dutta Rajiv
Published: December 2024

Silver nanoparticles are playing potential role in various fields such as medical, environmental, food, cosmetics, consumer goods, electronics, textiles etc. Due to which their production is getting hype for their multiple usage. Silver nanoparticles (AgNPs) traditionally can be synthesized by chemical and physical methods. But in past few decades, biological methods are utilized for the green synthesis of AgNPs. This research article shows the green synthesis of AgNPs which have been synthesized from leafs & flowers extract of Rosa indica & Catharanthus roseus. It has been reported, Rosa indica &Catharanthus roseus have possible therapeutic uses in many severe & common diseases such as cancer, diabetes etc. As both plant species have antibacterial, antifungal, antineoplastic & anticancer properties. In this process the leaf extract and flower extract of Catharanthus roseus and Rosa indica has been used as reducing agent, which was mixed with silver nitrate (AgNO3). Further, the characterization of synthesized AgNPs was done with the help of UV-Vis spectroscopy & Transmission Electron Microscopy (TEM). Based on these results the absorption spectra of Catharanthus roseus and Rosa indica were both compared to detect which had the most absorption peak. TEM analysis revealed NPs were spherical, big, segregated and of two sizes 19.2 nm and 15.2 nm and shows that the dried flower extract had potential to form huge, spherical and uncluttered nanoparticles better than that from leaf extract of the plant.
Impact of Bacterial Contamination and Antibiotic Resistance on the Quality of Giant Tiger Prawns (Penaeus monodon) from Vishakhapatnam Harbour, India
Authors: Dumpala Sridhar , Chintada Vivek , Bhasha Shanmugam , Lakshmi Vanum Jhansi , Viswasanthi Neredumilli , Erla Sindhu , Kakarlapudi Ramaneswari
Published: December 2024

Introduction: Spoilage of Penaeus monodon, a commercially significant species, is a major concern due to its negative impact on the seafood industry and public health. The microbial contamination of shrimp, especially from harbor environments, can reduce product quality and pose food safety risks. This study aims to identify the bacterial species responsible for the spoilage of P. monodon sourced from Visakhapatnam Harbour, with an emphasis on their antibiotic resistance profiles.
Methods: Bacterial isolates were obtained from the surface of P. monodon shrimp collected from Visakhapatnam Harbour. The total bacterial count was determined by serial dilution and plating on selective media, resulting in a bacterial count of 1.0602 × 104 CFU/g. Gram staining and biochemical tests were conducted on five isolated strains (M1, M2, M3, M4, M5) to determine their morphological characteristics and identify the species. Antibiotic susceptibility testing was performed to assess resistance profiles.
Results: All five bacterial isolates were found to be Gram-negative. The isolates were identified as follows: M1 – Enterobacteria spp., M2 – Achromobacter spp., M3 – Vibrio spp., M4 – Pseudomonas spp., and M5 – Vibrio parahaemolyticus. The total bacterial count for the shrimp samples was 1.0602 × 104 CFU/g. Antibiotic resistance testing revealed significant resistance, particularly against ampicillin and penicillin G.
Discussion: The presence of Vibrio and Pseudomonas, which are known to contribute to seafood spoilage, aligns with previous studies (Zhang et al., 2024). The antibiotic resistance observed in the isolates, particularly to commonly used antibiotics such as ampicillin, is concerning and reflects global challenges in controlling antibiotic-resistant pathogens in marine environments (Riaz et al., 2024). These findings underscore the need for effective preservation techniques and stricter regulations to ensure food safety and extend the shelf life of P. monodon.
Coconut Water (Cocos nucifera) as an Agent of Sex Reversal in Tilapia Larvae (Oreochromis niloticus)
Authors: Junda Muhammad , Ramadani Muh. Fajar , Rachmawaty Rachmawaty , Muis Abd , Ali Alimuddin
Published: December 2024

Tilapia is one of the leading commodities because it has high nutritional and economic value. The growth of male tilapia is faster than that of female tilapia. The research dealt with sex reversal of tilapia using coconut water. the study is important in the field of aquaculture production since, sex reversal of tilapia to male can cause improvement on the growth of tilapia. This implicates more harvest and could aid in food security. The effort to incease the percentage of tilapia males can be done by using a maculinization with 17α- Methyltestosterone. However, this chemical material is a type of drug which can cause environmental problem and food poisoning. So, it is important to use as an natural agent on masculinization process of tilapia male which is environmetally friendly, cheaper   and easy for application such as coconut water. The study aims to determaine the effect of coconut water (C. nucifera) and its optimal concentration on masculinization process of tilapia larvae. This study consider effect of coconut water on zootechnical performance of this tilapia such as survival rate, absolute weight gain and FCR. This study used compelately randomized design (CRD) with four treatments and three replications. There were four different treatments namely A (350 mL/coconut water); B (300 mL/L coconut water); C (250 mL/L coconut water and K (control treatment without coconut water immersion). Tilapia larvae were immersed in coconut water for 8 hours and then reared for 60 days at stocking density 30 fish larvae for each rearing container. The result showed that 300 mL/ L coconut water treatment increased the male sex ratio, survival rate and specific growth rate and reduced feed convertion ratio without a negative impact of survival rate of tilapia fry. In this study, the 300 mL/L cocunat water was the most optimal trreatment which produced a male sex ratio of 86.4%, survival rate of 91.1%, absolut weight gain of 61.3 grams, and feed convertion ratio of 1.17.
Feeding Behavior and Ovipositional Preference of the Tea Mosquito Bug, Helopeltis theivora (Hemiptera: Miridae) on Tea, Camellia sinensis (Theales: Theaceae)
Authors: Bharathi N. Santhana , Babu Annet , Prabhu A. , Karan S. Rishi , Ajith M. L. , Rabeesh T.P.
Published: December 2024

The main objective of the present study is to investigate the feeding behavior and ovipositional preference of the tea mosquito bug (TMB), Helopeltis theivora Waterhouse (Hemiptera: Miridae) on tea plants, Camellia sinensis (Theales: Theaceae). The feeding behavior studies revealed that the number of feeding punctures per day, feeding puncture diameter and total leaf area damaged by feeding gradually increased from the early nymphal stage to the adult stage. The maximum feeding punctures were produced by females (155.4 ± 3.29), while the minimum was produced by 1st instar nymphs (87.0 ± 3.74). All stages of tea mosquitoes exhibited significant feeding behavior in all time intervals, with the maximum feeding behavior observed between 12:01 and 15:00. The ovipositional site preference study showed that female TMBs mostly prefer sites between the 1st and 2nd leaf for egg laying, while sites between the 1st and bud, and below the 3rd leaf, are least preferred. These study results may lead to the development of new cultural practices for the better management of the tea mosquito bug in tea ecosystems.