bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of quality and efficiency of information resources of educational libraries
Authors: Veremchuk Olena V. , Pavlenko Tetiana S. , Nikolaienko Yaroslava M. , Matviichuk Oksana Ye. , Kozhedub Olena V.
Published: November 2021

The objective of the work was to analyze the quality of the information resources of educational libraries. Methods: A user survey of ten educational libraries was conducted to achieve this objective. Results: It was found that representatives of different target groups visit libraries for different purposes. Students and pupils use the library mainly to carry necessary textbooks and books, communicate, attend events. Academics, lecturers / professors, use it not only to obtain the book, but also to check references and read new publications in the library, use electronic resources, as well as to work on research. Sometimes pupils and students often need the help of library staff, indicating a lack of information literacy. Scholars, lecturers / teachers, are often able to fend for themselves. Electronic resources are the most effective, according to respondents, but visitors to educational libraries also continue to use traditional resources. Conclusions: Research shows that to increase the efficiency and quality of information resources of educational libraries, employees should focus their efforts on improving the information literacy of library users, as well as demonstrating the values of the library, inform about library services and maintain using information and communication technologies.
CICERO’NUN PRO LIGARIO ADLI SÖYLEVİNDE DEPRECATIO
Authors: KALAYCIOĞULLARI Serap
Published: November 2021

Pro Ligario (Ligarius Savunması), Caesar ile Pompeius arasındaki İç Savaş sonrasında Cicero’nun forumda yaptığı ilk dava konuşmasıdır ve aynı zamanda Cicero’nun söylevleri arasında bildiğimiz tek deprecatio (eylemin taammüden yapıldığının kabul edilmesi ve bağışlanma talep edilmesi) örneğidir. Çalışmada öncelikle Quintus Ligarius’u yargıya götüren süreç ve dava hakkında genel bilgi verilecektir. Daha sonra Cicero’nun davada Ligarius’u savunmak için başvurduğu deprecatio, antik kaynaklar ışığında tanımlanacaktır. Ardından savunma metni, kuramsal yapısı çerçevesinde deprecatio açısından incelenecektir. Nihayet Cicero’nun hangi ölçüde deprecatio’ya başvurduğu ve metnin tamamının bir deprecatio örneği olarak nitelenmesinin uygun olup olmadığı sorularına yanıt verilmeye çalışılacaktır.
La adicción al juego. Referentes claves para los procesos de intervención psicossocial
Authors: Miguel Pilar Blanco , Alés Yolanda Borrego
Published: November 2021

Introducción. ¿Es posible dejar de jugar? Esta es una pregunta que cada día se hacen muchas personas cuando su situación de juego les pone entre la espada y la pared, haciéndoles pensar si existe una salida real a su problema. En la actualidad, las posibilidades de tratamiento y prevención del juego patológico son claras y patentes, aunque debemos de tener en cuenta tres cuestiones básicas: la necesidad de hacer una correcta identificación del problema, una consideración profesional del caso y su remisión a los dispositivos especializados para su tratamiento. Objetivos. Identificar las situaciones en las que un adicto o adicta al juego  es capaz de plantearse dejar de jugar y por tanto iniciar el proceso de rehabilitación. Conocer qué implicaciones tiene esa decisión a nivel individual y familiar y que vienen a determinar el proceso de rehabilitación. Metodología. Se ha optado por una perspectiva metodológica que se sirva de estrategias que permitan conocer el fenómeno de la adicción al juego de mano de los propios afectados. De entre las técnicas posibles, se ha optado por la Historia de Vida y la Entrevista en Profundidad.  Resultados. De manera general hemos avistado que, tarde o temprano, el ludópata se ve obligado tener que confesar la adicción a su familia, ya que su situación de juego se hace insostenible. De igual modo, hemos podido ver que, afrontar el problema debe ir más allá del loable propósito de encararlo de forma individual, ya que esto no suele funcionar, y que es necesario, tanto la ayuda familiar, como la profesional para poder llevar a cabo el proceso de rehabilitación con una cierta garantía de poder superar la adicción. Conclusiones. Es fácil advertir que para dejar de jugar tienen que operarse un gran cambio en el pensamiento del ludópata, es decir, tomarse en serio el querer dejar de jugar y partir de ahí solicitar la colaboración de los profesionales (entre ellos el Trabajador Social); ayuda que debe ser complementada con el apoyo familiar, quedando ambos determinados como los principales factores a tener en cuanta en los procesos de recuperación.
PENGARUH KEPEMIMPINAN TERHADAP MOTIVASI MASYARAKAT DALAM MEMILIH KEPALA DESA (Hargomulyo, Gedangsari, Gunungkidul)
Authors: Widodo Widodo
Published: November 2021

Leadership and motivate of vital importance in governance wheel. Especially government mount the countryside or chief of village. " In order to the increasing of leadership and motivate hence ability Tekhnologi is big effort and its execution represent the effort with and is filling each other intergovernmental and Society. Through/passing  education program, development of science tekhmologi and also program the research, non-stoped to governmental push the make-up of ability tekhnologi. Meanwhile corporate world have to play role active in developing, linking and exploiting it in real activity" (President Soeharto, Political Oration of In front/ahead of conference DPR 15 August 1992).Leadership is an activity in group facility to reach the target with. In group facility, a leader have the mission to influence, to pushing, inviting, leading, moving and if require to force the others or group of so that/to be they do/conduct the related/relevant something that with the target attainment withMotivation is an process of somebody activity in the case of leading, guiding, influencing or controlling mind, feeling from behaviour to others of exist in under its observation. So that effective motivation is motivation which can or able to grow, looking after and developing effort and climate which co-operative in organizational life and in the end can improve the performancePlace in Countryside Hargomulyo,. Research Time of during year 2019. This research use the quantitative descriptive method to explain the independent variable influence of X to variable of dependen Y.Leadership of according to answer from responder determining answer A is 48,07% and responder determine the answer of concerning society Motivation to chosen the countryside head of equal to 46,83.
PENGARUH REKRUTMEN TERHADAP KINERJA KARYAWAN DI KOPERASI LEMBAGA PENGEMBANGAN PERBANKAN INDONESIA
Authors: Sarirati Putri , Baskara Fandy
Published: November 2021

This study aims to determine the effect of recruitment on improving cooperative performance. This analysis uses the independent variable, recruitment, and the dependent variable is employee performance.The population in this study were all supervisors, managers and associations of Indonesian banking development cooperatives. Samples were conducted using the non-probability sampling method using saturated samples obtained 30 people as samples. The type of data used is primary data. The testing method in this thesis uses IBM SPSS 22 processing. The results of the questionnaire have been tested for validity, reliability testing, data normality test, regression analysis and hypothesis testing.The results of the study prove that the proposed partial hypothesis is accepted because it shows significant test results. This means a significant increase in employee performance by 81.0% while 19.0% requires other factors.
PERANAN KESEJAHTERAAN DAN LINGKUNGAN KERJA TERHADAP KINERJA KARYAWAN PADA PT. BANK RAKYAT INDONESIA TBK CABANG PONDOK GEDE
Authors: Taufik Kemal , Dhika Adrian
Published: November 2021

The important employee welfare defend employee so that doesn't move to company other, freshment gift manner to officials with appropriate work environment situation and resort condition. supposed good work environment can spur on tall official performance. This problem formulation : 1) What found welfare part towards employee performance in PT. Bank Rakyat Indonesia Tbk Cabang Pondok Gede?; 2) What found work environment part towards employee performance in PT. Bank Rakyat Indonesia Tbk Cabang Pondok Gede?; 3) What found welfare part and work environment according to together towards employee performance in PT. Bank Rakyat Indonesia Tbk Cabang Pondok Gede? This watchfulness aim : 1) To detect welfare part magnitude towards employee performance in PT. Bank Rakyat Indonesia Tbk Cabang Pondok Gede. 2) To detect work environment part magnitude towards employee performance in PT. Bank Rakyat Indonesia Tbk Cabang Pondok Gede. 3) To detect welfare part magnitude and work environment according to together towards employee performance in PT. Bank Rakyat Indonesia Tbk Cabang Pondok Gede. Conclusion : 1) Found connection significant welfare towards employee performance in PT. Bank Rakyat Indonesia Tbk Cabang Pondok Gede, with indicator-indicator well-being guarantee, work arrangement, placidity guarantee, organization progress, creat work environment, complete work facilities, well-being facilities, official library, official education, official house, matter need, official hope, pension, official work quality and economy security. 2) Found connection significant work environment towards employee performance in PT. Bank Rakyat Indonesia Tbk Cabang Pondok Gede, with indicator-indicator work smoothness, light, temperature at work, draught, cool taste, planology, temperature, voice, illumination, noise, illumination enough, illumination less, air transfer enough, air transfer can refresh physical and calm work environment. 3) Found positive connection and significant welfare and environment work according to together towards employee performance in PT. Bank Rakyat Indonesia Tbk Cabang Pondok Gede, with indicator-indicator education, practice, nutrient and well-being, income, self development, management, government wisdom, official fellow connection, connection with pmpinan, supervision connection, supervise, official know-how, working procedure, increase connection and incentive system.
PENGARUH STRES KERJA TERHADAP KINERJA KARYAWAN PADA FASTGLOBAL EXPRESS
Authors: Azhari Munir
Published: November 2021

The Influence of work Stress on Employee Performance at Fastglobal Express. Based on the significant testbetween the independent X variable (work stress) and the dependent Y variable (employee performance) for the workStress variable (X), the t-count value is 22.960 while the t-table value for N = 100 is 1.666 then 22.960 1.666 witha significant effect of t 0, 05 or t count t table. Based on the results of the t test that in fact the work stress variable(X) has a significant relationship to the Employee Performance variable (Y) where the value of t is greater than t table, thus it can be concluded that Ho is rejected and Ha is accepted. The results of the analysis of the work stress obtained a value of 0.918 so that it can be concluded that it is positive and the level of influence is forceful.
ANALISIS RAGAM PRODUK DAN KUALITAS INFORMASI TERHADAP MINAT BERBELANJA DISITUS ONLINE STORE SHOPEE (STUDI PADA PT REYCOM DOCUMENT SOLUSI DI JAKARTA)
Authors: Miharja Arif , Kurniawan Danu Adi , Maolani Dian , Rosharia Darrinh
Published: November 2021

The title of this research is Analysis of Product Variety and Quality of Information on Shopping Interests on the shopee online store site (Study on Employees of PT Reycome Document Solusi in Jakarta). Does the variety of products and quality of information affect the interest in shopping at the Shopee online store site? The purpose of this study was to determine the Analysis of Product Variety and Quality of Information on Shopping Interests.The population in this study were online users, namely employees of PT Reycome Document Solusi in Jakarta who had made purchases on the online Store Shopee site. According to the opinion of the roots, the sample requirements used in this study were 64 people. This research is an associative study using a quantitative approach. This research is categorized as survey research, in which the research instrument is a questionnaire. Validity test using CFA (Confirmatory Factor Analysis Model), using the SPSS application. The results of this study indicate that Product Variety has no significant effect on Shopping Interest on Shopee's online store site with test results (t) of 0.970 greater than 0.05, and information quality has a significant effect on Shopping Interest on Shopee's online store sites with test results (t) of 0.003 is less than 0.05. Thus the Information Quality variable (X2) is the most dominant variable influencing the shopping interest on the Shopee online store site.
Manajemen Laba dengan Indikator Penyebabnya
Authors: Purwiyanto Fitri , Wijayanti Inung , Nauli Stephani
Published: November 2021

Tujuan penelitian ini adalah untuk menguji pengaruh FCF, GCG dan Leverage terhadap manajemen laba.  Penelitian ini merupakan replikasi penelitian-penelitian  sebelumnya. Data yang digunakan adalah laporan IICG dari perusahaan peserta CGPI yang mempubliksikan laporan keuangannya pada periode 2012-2018. Metode purposive sampling digunakan untuk menghasilkan 13 perusahaan dengan jumlah 91 data observasi. Metode regresi data panel dan  uji asumsi klasik  digunakan  untuk menganalisis data dengan  tingkat kepercayaan sebesar 95%. Hasil penelitian menunjukkan bahwa  FCF, GCG dan leverage secara simultan   mempunyai pengaruh signifikan terhadap manajemen laba. Dengan  adjusted R2 sebesar 0,417 berartai bahwa FCF, GCG dan Leverage dapat memepengaruhi manajemen laba sebesar 41,7%, sedangkan 58,3% merupakan variabel lainnya. Hasil pengujian secara partial menunjukkan bahwa   masing – masing variabel FCF, GCG, Leverage juga mempunyai pengaruh signifikan  negatif terhadap manajemen laba. Manajemen Laba dengan Indikator Penyebabnya
ANALISIS KEMANDIRIAN DAN KEMAMPUAN KEUANGAN DAERAH TERHADAP KEMISKINAN DI KABUPATEN BOGOR
Authors: Handayani Milda , Sari Rycha Kuwara , Sulistyowati Ari
Published: November 2021

The regional government holds the mandate of the central government in implementing regional autonomy and has a role in resource management which in turn can improve the welfare of the community. To be able to improve the welfare of the community, one measure can use an analysis of regional financial independence and regional financial capacity by assessing the original regional income compared to total regional income and the balance fund. And see the effect on the percentage of poor. The results obtained, the regional financial independence of Bogor Regency is still in the range of 0% - 25% so that it is categorized as very low, while the regional financial capacity is at 24.07% or it can be said that it is sufficient. Meanwhile, the results of multiple linear regressions for regional financial independence and regional financial capacity have an influence on the percentage of poor people. The expected result is that Bogor Regency can do more to increase its base of tax and retribution revenues so as to minimize budget dependence from the central government and local governments.
PENGARUH ETOS KERJA DAN DISIPLIN KERJA TERHADAP KINERJA PEGAWAI (STUDI PADA PEGAWAI DINAS PEKERJAAN UMUM KOTA BEKASI)
Authors: Masrifah Ifah
Published: November 2021

Tujuan dari penelitian ini adalah (1) etika profesi dalam menjalankan tugas pegawai negeri sipil di Bekasi, (2) prinsip bisnis dalam kaitannya dengan pekerjaan umum oleh pegawai di Bekasi, (3) pegawai pemerintah kota Bekasi, etika kerja. Penelitian ini mencakup hubungan kausal dengan menggunakan pendekatan kuantitatif. Survei tersebut melibatkan 96 pekerja konstruksi publik di kota Bekasi. Pengumpulan data dilakukan dengan menggunakan kuesioner yang telah diuji validitas dan reliabilitasnya. Metode analisis data yang digunakan adalah regresi berganda. Berikut adalah hasil penelitiannya: (1) etos kerja berpengaruh positif terhadap kerja pegawai Dinas Sumber Daya Manusia Kota Bekasi; Hal ini dibuktikan dengan koefisien beta sebesar 0,256 (β). p = 0,000 dan R2 adalah 4,1%. (2) Disiplin kerja berpengaruh positif terhadap produktivitas pekerja di bidang konstruksi umum kota Bekasi. Hal ini dibuktikan dengan koefisien beta (β) 0,210, p = 0,004 dan R2 2,7%. (3) Etika kerja dan disiplin kerja berpengaruh positif terhadap efisiensi pekerjaan umum di kota Bekasi. Hal ini dibuktikan dengan koefisien beta (β) variabel etos kerja sebesar 0,234 dan p = 0,001. Koefisien beta (β) untuk variabel pekerjaan adalah 0,181 dan p = 0,009. 6,2% R2.
SISTEM AUDIT ISO 9001 : 2000 INTERNAL DAN EKSTERNAL PENDEKATAN PADA PENINGKATAN KEPUASAN PELANGGAN (STUDI KASUS PADA PT. MARGA MAJU JAYA)
Authors: Azhari Munir
Published: November 2021

Munir Azhari, ISO 9001:2000 Internal and External Audit System Approach to Improve Customer Satisfaction.Quality is an image which is very hungered for each. Every flexible pavement in giving service to customer, goodnessin the case of product service and also service. Congeniality quality of in flexible pavement service industries contextcan be defined to through various approach, but in principle is reaching of according to among result of activity tobe delivered by customers to service company.ISO 9000 representing one of the management system quality of which is on this time become especial choice toflexible pavement service which wish to apply concept from management system quality of consistently and is systematic.The company that has the ISO must commit that is all kind from the lower level until top management have to runthe ISO system in right way. In this chase PT. Marga Maju Mandiri runs ISO system on the tract. The relationshipbetween ISO 9001 : 2000 implementing with customer satisfaction can be see as the result such as repeat order, thatis the customers have got the satisfaction. PT. Marga Maju Mandiri has been running the philosophy of the ISO 9001: 2000 ,they are; what you do you write, what you write you do, what you did you record and safety factor.The implementation of the quality management concept that has been carried out properly and effectively throughfull commitment from the company management in service orientation at PT. Marga Maju Mapan will produceasphalt services whose quality is closer to meeting the satisfaction desired by customers in accordance with workstandards and specifications.
PENGARUH GOOD CORPORATE GOVERNANCE TERHADAP PROFITABILITAS PERUSAHAAN PADA PT. BANK CENTRAL ASIA, TBK PERIODE TAHUN 2015-2020
Authors: Sarirati Putri , Yunianti Kristin , Feriandy Feriandy
Published: November 2021

This research aims to examine the effect of Good Corporate Governance (Institutional Ownership and Board of Directors) on Profitability at PT. Bank Central Asia, Tbk for the period 2015-2020. This research uses secondary data from PT. Bank Central Asia, Tbk in 2015- 2020. The data analysis technique used is the classical assumption data and multiple linear regression test. The results of this research indicate that institutional ownership and the board of directors have no significant effect on profitability.
Rule-Based Leadership-Management Style of Administrators and the Entrepreneurial Spirit of Employees
Authors:   Professor, School of Business, Divine Word College of Laoag, Ilocos, Philippines., Abun Damianus
Published: November 2021

The study aimed to determine the influence of rule-based leadership management toward the entrepreneurial spirit of the employees of the Divine Word College of Laoag. To deepen the understanding and concept of the study, literature was reviewed. Theories of the study were established. The study used the descriptive correlational research design and used questionnaires to gather the data. The study found that rule-based leadership management of the administrators is high but the entrepreneurial spirit of the employees is moderate. The study concludes that the higher the bureaucratic or rules-based leadership- management is, the lower the entrepreneurial spirit of the employees become. In terms of the correlation between rule-based leadership management and entrepreneurial spirit, the study found that there is a significant correlation. Rule-based leadership management affects the entrepreneurial spirit/mindset of employees. Therefore the hypothesis of the study is accepted.
Policies Contribution and Integrated Quality Management to Improve the Quality of Services in Primary and Secondary Education in the Banten of Province 21 St Centuruy The Era of the Revolutionary 4.0
Authors:   Professor, Faculty of Teacher Training and Education Sultan Ageng Tirtayasa of University, Sudadio, M. Pd Prof. Dr.
Published: November 2021

The success of an organization is largely determined by the management model that is applied, sedangkan keberhasilan manajemen ditentukan oleh pemimpinnyaespecially in primary and secondary education which has a central and very strategic role for the continuation of the next higher education. this strategic role will be more effective if educational institutions can implement integrated quality management education services in the 21st century revolutionary 4.0, This management model is considered appropriate, because this management focuses on customer satisfaction, both internal customers and external customers.
The Role of Job Satisfaction as Mediating of Financial Compensation and Communication Competence on the Agricultural Instructor Performance
Authors:   Faculty of Economics and Business, Universitas Syiah Kuala, Indonesia, Ibrahim Mahdani
Published: November 2021

This study aims to determine the impact of financial compensation and communication competence on employee performance. job satisfaction is involved as a mediator. A total of 165 employees were involved as respondents in this research proportionally. Data analysis through structural equation modeling (SEM). The results showed that financial compensation plays a very important role in employee satisfaction and performance. Communication competence also has a positive effect on satisfaction and performance. Satisfaction itself is also the main key that has an impact on improving performance. In addition to being a key factor, job satisfaction also plays a role in connecting financial compensation to employee performance. while on the relationship of communication competence to performance, job satisfaction is considered unimportant. We suggest to the management that in order to improve the performance of agricultural extension workers, financial compensation should get more attention. Likewise, communication competence needs to be improved through employee training and development.
Autistic Spectrum Disorder and Current Laws in Brazil
Authors:   Specialist, Santa Úrsula University in Rio de Janeiro-RJ, Brazil, Bogossian Tricia
Published: November 2021

The objective of the work was to analyze the autistic spectrum disorder and the current laws in Brazil. In addition to the concept of TEA, a special law composed of a total of 8 (eight) articles establishes the inherent rights of these people, and in its 2nd article, establishes guidelines for national policies, including the intersectoriality of service actions of development; community participation; comprehensive attention to the needs of autistic patients, etc. The type of study is a systematic review, research of this type has the primary objective of exposing the attributes of a given phenomenon or statement among its variables. Thus, it is recommended that it presents characteristics such as: analyzing the atmosphere as a direct source of data and the researcher as a switch instrument; not to broker the use of statistical artifices and methods, having as a greater apprehension the interpretation of phenomena and the imputation of results, the method should be the main focus for the approach and not the result or the fruit, the appreciation of the data should be achieved from intuitively and inductively through the researcher
Inequidades : la educación primaria de niñas y niños jornaleros agrícolas migrantes
Authors: Rojas Rangel Teresa de Jesús
Published: November 2021

Este libro condensa años permanente búsqueda por encontrar respuestas a preguntas surgidas desde el primer acercamiento con la población jornalera migrante; familias hambrientas y cansadas que regresan a sus galeras después de largas jornadas en los campos agrícolas, con profunda resignación y desesperanza. Niños que no tienen tiempo de hablar, jugar o comer, mucho menos para ir a la escuela. A pesar de esto algunos de ellos, con sus escasas fuerzas, después de terminar sus jornadas, se levantan el rostro y se peinan para dirigirse a los improvisados salones
Jurisdições e mudanças de subordinação na administração da Capitania do Rio Grande: análise das correspondências entre autoridades coloniais (1695-1705)
Authors: Franklim da Silva Tyego
Published: November 2021

Este artigo tem por objetivo analisar o processo de mudança de subordinação da capitania do Rio Grande no ano de 1701 e suas consequências no processo de territorialização da capitania em um contexto de aplicação de políticas defensivas, retorno das concessões de sesmarias nos sertões e das ações dos oficiais do Terço dos Paulistas. Para tanto, serão analisados documentos oficiais da administração colonial e régia, bem como correspondências entre as autoridades. O aporte teórico embasa-se, principalmente, nos conceitos de jurisdição, centro e periferia, relevantes para se compreender o processo de mudança de subordinação e da nova configuração jurisdicional que a capitania do Rio Grande passou a incorporar como uma das capitanias anexas a Pernambuco. Como recortes temporais, considerar-se-á o início do governo do capitão-mor Bernardo Vieira de Melo (1696) e o final do mandato de seu sucessor, Antonio de Carvalho e Almeida (1705), período em que ocorre a mudança administrativa e percebe-se maior intensidade de correspondência tratando do assunto entre as autoridades coloniais.
Function of Microscopic Carpal Tunnel Release in Cases Resistant to Conservative Therapy
Authors: Zeb Jehan , Ullah Muhammad , Shoaib Muhammad , Shah Syed , Shah Walayat , Jamal Bakth , Ali Saad , Zafar Aysha
Published: November 2021

Purpose: To determine the outcome of microscopic carpal tunnel release in patients with carpal tunnel syndrome who failed to respond to conservative treatment.

Methodology: This descriptive case series was carried at Department of Neurosurgery, D.H.Q Hosptial Charsadda over 1 year from Jan 2019 to Dec 2020, indicate the sampling method used to select the study participants involving 94 patients; both men and women with ages in the range 30-70 years diagnosed of carpal tunnel syndrome who failed to respond to conservative treatment and were planned for surgical release. Microscopic CTS release was performed and outcomes were assessed in terms of improvement in VAS score for wrist pain, symptom severity score and function status scale 3 and 6 months after the surgery. Recurrence of symptoms was also noted. A written informed consent was obtained from every patient. Indicate the method of data collection and data analysis

Findings: The mean age of the patients with carpal tunnel syndrome was 41.6±7.9 years. There was slight female predominance with male to female ratio of 1:2.1. History of diabetes was recorded in 29 (31.0%) patients while 34 (37.0%) patients were obese. Right hand was more frequently involved (53.0%) than the left hand (47.0%). The mean VAS score for wrist pain reduced from 7.9±1.2 at baseline to 1.8±0.7 3 months after the surgery (p- value<0.001). Similar improvements were also noted in symptom severity score (3.8±0.8 to 1.6±0.8; p- value<0.001) and function status scale (2.7±0.8 to 1.5±0.8; p-value<0.001) at the end of 3 months after the surgery. Recurrence was not observed in any patient at the end of 6 months follow-up.

Recommendation: Microscopic carpal tunnel release was found to relieve patient’s symptoms and improve wrist function yet with minimal scarring and without recurrence which advocates its preferred use in future practice provided necessary surgical skills and hardware are available.
Pathogenesis of Dengue virus in Host immune system and its genomic variation
Authors: Sohail Sohail , Farooq Mukarram , Sohail Fareeha , Rana Hamza , Karim Husnain , Haider Tousif , Shakir Ahmed , Zafar Mahrukh , Saadat Samrah
Published: November 2021

Dengue viruses are the most prevalent arthropod-borne viral diseases in humans, infecting 50-100 million people each year. Its serotypes are the most common causes of arboviral illness, putting half of the world's population at risk of infection. Because there is no vaccine or antiviral medicines, the only way to manage the disease is to reduce the Aedes mosquito vectors. DENV infection can be asymptomatic or cause a self-limiting, acute febrile illness with varying degrees of severity. High fever, headache, stomach discomfort, rash, myalgia, and arthralgia are the typical symptoms of dengue fever (DF). Thrombocytopenia, vascular leakage, and hypotension are symptoms of severe dengue, dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS). Systemic shock characterizes DSS, which can be deadly. Dengue virus infection pathogenesis is linked to a complex interaction between virus, host genes, and host immune response. Major drivers of disease vulnerability include host factors such as antibody-dependent enhancement (ADE), memory cross-reactive T cells, anti-DENV NS1 antibodies, autoimmunity, and genetic variables. The NS1 protein and anti-DENV NS1 antibodies were thought to be involved in the development of severe dengue. The progressive infection may change the cytokine response of cross reactive CD4+ T cells. The need for dengue vaccines that can generate strong protective immunity against all four serotypes is required. To create such vaccines, a thorough understanding of DENV adaptive immunity is required. Structural and functional research have shown that the degree of prM protein cleavage as well as the ensemble of conformational states sampled by virions influence DENV sensitivity to antibody-mediated neutralization, which has crucial implications for vaccine formulation.
KAYSERİ'DEN YEREL ÜRETİM İKİ LAHİT
Authors: ALTUN Özge
Published: November 2021

Kayseri ilinde inşaat çalışması sırasında iki mermer lahit bulunmuş ve Kayseri Müze Müdürlüğü tarafından yapılan kurtarma kazısı sonucu açığa çıkarılarak müzeye taşınmıştır. İnşaat çalışması sırasında iş makinelerinin fark etmemesi sonucu her iki lahitte ciddi biçimde zarar görmüştür. Bununla birlikte mevcut parçalar birleştirildiğinde lahitlerin neredeyse tamamına yakını elde edilmektedir. Kayseri Müze Müdürlüğü talebimim doğrultusunda eserlerin literatüre kazandırılmasının faydalı olacağını düşünerek izin vermiş ve gerekli yardımı yapmıştır. Bu doğrultuda bu çalışmanın yapılması için gerekli izinleri veren Kayseri Müze Müdürlüğüne teşekkür ederim.
Çalışma içinde değerlendirilen lahitler, Lahit 1 ve Lahit 2 olarak adlandırılmıştır. Lahit 1, girlandlı lahitler grubuna dâhil olmakla birlikte cephelerinde kullanılan girlandların birbirinden farklı içerikleri ve işleniş biçimleri açısından faklıdır. Lahit 2 ise bir yüzünde girlandların diğer cephelerinde ise figürlerin süsleme unsuru olarak kullanılması ile spesifik özellikler göstermektedir. Ayrıca lahit 2 içinde bulunan sikkeler, lahitin bir kereden fazla kullanıldığı ve kullanım dönemleri hakkında bilgi vermektedir.
Bu bağlamda çalışılan iki lahitin hem Anadolu lahit üretimindeki çeşitliliği hem de bölgesel özellikleri göstermesi açısından önemli bir yere sahip olduğu söylenebilir.
Lahitler, benzer örnekleri ile analoji yapılarak değerlendirilmiştir. Ancak eserlerin özgün nitelikleri dolayısıyla benzer örnekler sayıca kısıtlı kalmıştır. Çalışma ile amaçlanan lahitlerin detaylı tanımlaması ile yapıldıkları dönem ve kulanım durumları hakkında öneri sunabilmektir. Ayrıca elde edilecek sonuçlar ışığında bölgenin ölü gömme gelenekleri hakkında literatüre katkıda bulunmaktadır.
Entre conflitos e harmonias: o assistencialismo empresarial na América Latina
Authors: Andújar Andrea Norma , Palermo Silvana A.
Published: November 2021

Este dossiê aborda o assistencialismo empresarial na Argentina, no Chile e no Brasil. Seu objetivo é reconsiderar sua complexidade e relevância, com base em investigações cuja riqueza empírica estimula o debate sobre as categorias com as quais este tema foi conceitualizado: paternalismo, "company welfare", assistencialismo empresarial, entre outros. Trata-se, portanto, de reconstruir alguns dos capítulos da complexa relação entre capital e trabalho nestas nações, em que conflitos e harmonias convergem em espaços de trabalho heterogêneos e diversos atores sociais. O dossiê reúne artigos que, mesmo sem ter deliberadamente visões comparativas, estimulam diálogos entre experiências de diferentes casos nacionais, em diversos ramos produtivos e segmentos de trabalhadores durante o século XX. Reafirma a necessidade de historicizar a vocação empresarial assistencialista através de ensaios, múltiplas iniciativas e processos contingentes, ponderar seu alcance e limites, e reconsiderar a agência histórica, tanto de empresários quanto de trabalhadores. O dossiê está organizado de acordo com um critério temático – sensível às comparações por tipo de atividade – e ao mesmo tempo cronológico - atento às variações do assistencialismo empresarial em um mundo transformado, mas tão turbulento quanto incerto.
Johann Wier
Authors: Valente Michaela
Published: November 2021

This book deals with a fascinating and original claim in 16th-century Europe. Witches should be cured, not executed. It was the physician and scholar Johann Wier (1515-1588) who challenged the dominant idea. For his defense of witches, more than three centuries later, Sigmund Freud chose to put Wier’s work among the ten books to be read. According to Wier, Satan seduced witches, thus they did not deserve to be executed, but they must be cured for their melancholy. When the witch hunt was rising, Wier was the first to use some of the arguments adopted in the emerging debate on religious tolerance in defence of witches.

This is the first overall study of Wier which offers an innovative view of his thought, by highlighting Wier’s sources and his attempts to involve theologians, physicians, and philosophers in his fight against cruel witch hunts. Johann Wier: Debating the Devil and Witches situates and explains his claim as a result of a moral and religious path as well as the outcome of his medical experience. The book aims to provide an insightful examination of Wier’s works to read his pleas emphasizing the duty of every good Christian to not abandon anyone who strays from the flock of Christ. For these reasons, Wier was overwhelmed by bitter confutations, such as those of Jean Bodin, but he was also celebrated for his outstanding and prolific heritage for debating religious tolerance.
Cycling Pathways
Authors: Dekker Henk-Jan
Published: November 2021

In an effort to fight climate change, many cities try to boost their cycling levels. They often look towards the Dutch for guidance. However, historians have only begun to uncover how and why the Netherlands became the premier cycling country of the world. Why were Dutch cyclists so successful in their fight for a place on the road? Cycling Pathways: The Politics and Governance of Dutch Cycling Infrastructure, 1920-2020 explores the long political struggle that culminated in today’s high cycling levels. Delving into the archives, it uncovers the important role of social movements and shows in detail how these interacted with national, provincial, and urban engineers and policymakers to govern the distribution of road space and construction of cycling infrastructure. It discusses a wide range of topics, ranging from activists to engineering committees, from urban commuters to recreational cyclists and from the early 1900s to today in order to uncover the long and all-but-forgotten history of Dutch cycling governance.
Case Series of Pancytopenia Secondary to Pernicious Anemia
Authors: Jian Low Qin , Weng Eric Hong Qiu , Wee Cheo Seng
Published: November 2021

Pernicious anaemia is an autoimmune disorder where vitamin B12 deficiency is caused by autoantibodies that interfere with vitamin B12 absorption by targeting intrinsic factor or parietal cells or both. It is commonly associated with anaemia, rarely pancytopenia. Here we reported two cases of pancytopenia due to undiagnosed pernicious anaemia. The first case was a 26-year-old man presented with lethargy and reduced effort tolerance, associated with postural giddiness and palpitation. Clinically, he was pale with no other findings. On blood investigations, the patient has diagnosed pancytopenia secondary to pernicious anaemia.He was treated with daily subcutaneous injection of vitamin B12 cyanocobalamin 1 mg for one week followed by weekly injection for a month and subsequently with lifelong monthly subcutaneous injection. After receiving 2 weeks of B12 replacement, his full blood count had normalized and his symptoms resolved. The second case was a 65-year-old man presented with yellowish discolouration of the eyes with lethargy. On examination, he was pale with jaundice. On blood investigations, the patient has diagnosed pancytopenia secondary to pernicious anaemia. He was started with an intramuscular injection of 1000 mcg vitamin B12 replacement daily for one week followed by monthly for 6 months. After one week of B12 replacement, his full blood count had normalized. He was started on lifelong 3 monthly injections of vitamin B12 replacement and he remained symptom-free. Patients with pernicious anaemia often present with general signs and symptoms which occurinsidiously. It is important that early diagnosis is made to avoid harmful complications such as neuropsychiatric disorders.
Detection of Four Mismatched Nucleotides between DENV4 Specific C-prM Primer (rTS4) and Current DENV 4 Sequences in Sabah
Authors: Aung Tin Sabai , Emran Amalina , Thein Tin Tin , Gintarong Timothy Jr , Kobayashi Nobumichi
Published: November 2021

Dear Sir/ Madam,

Dengue is the mosquito borne viral disease caused by dengue virus serotype 1 to 4 (DENV 1 to 4).

Dengue outbreaks are common in both east and west Malaysia. Between July 2016 and December 2017, 200 serum samples positive for dengue by rapid test were collected from patients in Sandakan and Kudat of Sabah state during dengue outbreaks. Serotypes of the dengue viruses were determined by reverse transcriptase polymerase chain reaction (RT-PCR) followed by nested PCR. We used C-prM primers designed by Lanciotti et al1 and later redesigned by Chien et al2. We detected all the four dengue serotypes with PCR products with specific sizes in gel electrophoresis. However, in four samples, no serotype-specific band was amplified by the nested PCR, while they were dengue-positive in RT-PCR showing 511 bp amplicon. We first presumed that these DENV might belong to a new DENV serotype, accordingly nucleotide sequences of the 511 bp amplicons of the four samples were determined. As a result, all the four samples (K35, K81, S23 and K75) (K and S stands for Kudat and Sandakan respectively) were found to belong to DENV4. We aligned the sequences of these samples with that of DENV 4 reverse primer (rTS4) (Fig.1).

The DENV4 specific primer  rTS4 was found to have four mismatched nucleotides to the current DENV4 sequences. Therefore, for the local DENV4 in Sabah, we recommend a modified  rTS4 reverse primer TTCTCCTATTCAAGATGTTT (or CTTCTCCTATTCAAGATGTTTAAC) (red nucleotides are modified ones) to be included in the dengue C-prM primers in future research.
The Silent Expansion of Rabies in Borneo
Authors: Ahmed Kamruddin , Ibrahim Mohd Yusuf
Published: November 2021

Among dengue, malaria, leptospirosis, cholera and tuberculosis, we often forget about rabies. Globally, an estimated 60,000 people die of rabies annually, and more than half of these deaths occur in Asia1. Among all infectious diseases, rabies is most fatal where the mortality rate of human rabies is 100%. On the other hand, rabies is 100% preventable if vaccine is administered timely. Rabies has been known to occur in Peninsular Malaysia since 1884, and since 1924 human rabies cases have been recorded. Most of these cases occurred in states bordering Thailand, which is highly endemic for rabies2. The incidence rose markedly in late 1945 with the reoccupation by Allied Forces, many of whom had come from India had brought their dogs with them3. A major outbreak of rabies occurred in Province Wellesley and Perak in 1945, and subsequently in Selangor in 19523 The total human death from rabies in Malaya from 1946 to 1952 was only 253. Outbreak was controlled by compulsory mass vaccination of dogs, stringent legislation, intensive stray-dog destruction, and mass education. These prompted a National Rabies Control Programme of compulsory vaccination of all dogs and a rigorous programme of destruction of stray dogs3 . However, small outbreaks and sporadic cases of animal and human rabies continued to occur in the northern states of Perlis, Kedah and Kelantan and also in Selangor2 . With continuous efforts, Malaysia was declared rabies free in 2013. However, rabies outbreak occurred in July 2015 in three states â€“ Perlis, Kedah and Penang. After several years this was a new challenge for the authorities and was resolved by November 2015 after extensive vaccination and culling of dogs and awareness campaign4 . The outbreak in Perlis and Kedah were hypothesized to have originated from neighbouring Thailand by land movement, but the outbreak in Pulau Penang was hypothesized to have originated by sea through fishermen boat4.  It is noticeable that the first rabies outbreak in Terengganu in 1996 was also by dogs from Thailand brought by fishermen boat4.
Good Recovery of Prostate Carcinoma with Spine Metastases to T9 Following Laminectomy
Authors: Wafiuddin Muhammad , Khan Ed Simor , Faizal Ahmad , Jasni Jasfizal , Loong Loh Li
Published: November 2021

Prostate carcinoma is a common health issue that can metastasise in the spine. A 65-year-old male was diagnosed with prostate carcinoma and two years later he developed a progressive neurological deficit over the bilateral lower limb. He experienced severe back pain, became paraplegic and the quality of life was severely impaired. Radiographic investigations were done and revealed osteoblastic bone metastasis at thoracic vertebrae with spinal cord compression. The patient underwent surgical decompression surgery at the T9 level mainly for pain control. Six months post-surgery not only the pain was well controlled but patient able to ambulate with walking aid. It is a rare post-operative result as the neurological recovery in a patient with complete paralysis is less than 3%. This type of recovery is possible when the cause of the neurological deficit is mainly mechanical compression from tumour rather than cord ischaemia from traumatic injury.
"A Double-Edged Sword": A Case Report on Liver Injury Side-Effect of Anti-Tuberculosis Drug on Liver Tuberculosis Patient
Authors: Ibrahim Azlina , Payus Alvin Oliver
Published: November 2021

Hepatic involvement in extra-pulmonary tuberculosis (TB) is rare, even in the endemic area. It has a high mortality rate as it can easily be misdiagnosed due to its rarity and non-specific presentations, and the treatment can be challenging for its hepatotoxic side-effect. A 55-year old man who was newly diagnosed with AIDS and pulmonary TB which complicated with anti-TB-induced transaminitis, presented with a few weeks history of fever and persistent diarrhoea. It was initially treated as microsporidia infection but the symptoms persisted despite given antiparasitic agent for more than a week. He was subjected to computed tomography (CT) scan of the abdomen and noted multiple hypoechoic lesion at multiple segments of the liver, which later confirmed to be liver TB by liver biopsy. As he could not tolerate Akurit-4 (Rifampicin 150 mg, Isoniazid 75 mg, Pyrazinamide 400 mg and Ethambutol 275 mg), the second-line treatment was given instead. He is currently well on regular clinic appointment. The objective of this case report is to share the rare occurrence of hepatic TB and the difficulty to treat it as the hepatotoxic effect of anti-TB medications complicate the liver damage due to the infection.
The Impact of Sleep Quality on the Occupational Fatigue Outcome among Healthcare Shift Workers in Critical Care Setting
Authors: Chiang Hoon Teo , Tuan Kamaruzaman Tuan Hairulnizam , Abdullah Sarimah binti
Published: November 2021

Introduction

Occupation-related fatigue and sleep loss are common among shift workers in the emergency department (ED), who deliver round-the-clock critical care service to patients. These factors affect their performance and impose an unnecessary hazard to patients, while also endangering themselves.
A Systematic Literature Review on Technology-Enhanced Learning in Medical Education
Authors: Ohn May Honey , Ravindran Bareth , Zhi Wei Chan , Maung Ohn Khin , Pey Luen Ng
Published: November 2021

This systematic review was aimed to evaluate the effectiveness of technology-enhanced learning (TEL) used in medical teaching for undergraduate medical students. The objectives are to (a) identify various teaching modalities which are used to enhance TEL; (b) evaluate whether TEL is more effective than traditional learning (TL) in cognitive and affective learning domain outcome. The empirical studies were searched in the following databases: Google Scholar, MEDLINE, ERIC, ProQuest, Cochrane Library and Scopus. All papers published from 2008 to 2018 were included. From eligible studies, the study design, study field, study population, intervention methods, type of assessment and learning achievement were abstracted and summarized the information. The search results were independently reviewed by two authors. From a pool of 1384 articles, 43 eligible articles were identified, enrolling 7292 undergraduate medical students examining comparative study between TEL and traditional learning. The results showed that there was a high degree of heterogeneity seen amongst the included studies in terms of TEL modalities used. The majority of intervention studies favoured online resources, while the rest used various offline multimedia electronic devices, virtual simulations and blended modes. Overall findings showed promising data that TEL is better than TL with regards to knowledge gain and skill acquisition, as well as providing higher student satisfaction. In all, the findings present blended learning in a positive and promising light in time, particularly where systematic reviews on technology-enhanced learning in the field of the undergraduate medical programme have produced mixed result.