bluuebunny/crossref_metadata_2025 huggingface dataset:
Synergistic Effect of Three Medicinal Plant Extracts and Their Nutritional Indices on the Tribolium castaneum Herbst and Ephestia kuehniella Zeller
Authors: HOSSEINI Elena , LOTFOLLAHI Sana , ARAMIDEH Shahram , HOSSEINZADEH Abbas
Published: December 2024

Chemical control of stored pests causes environmental pollution, contamination of stored products and endangering human health. Botanical compounds are one of the suitable alternatives for this aim. In this study effects of eucalyptus, rosemary and mentha extracts alone and in mixed of them on T. castaneum and E. kuehniella were evaluated. Due to our research, the most effect of rosemary extract on the T. castaneum adult, and eucalyptus on the 3rd and 4th instars larvae of E. kuehniella observed. The most significant synergetic on the T. castaneum adult was the combination of ME, MR and ER. Also, the most synergetic effect of extracts on the 3rd and 4th instar larvae of E. kuehniella were related to ME, and MR and ME respectively. The lowest amount of T. castaneum adult Feeding deterrence percentage indices (FDI) and Approximately Digestibility (AD) were observed in rosemary extract and the lowest amount of Efficiency of conversion of ingested food (ECI), Relative consumption rate (RCR) and The Relative growth rate (RGR) was related to eucalyptus extract. The lowest amount of E. kuehniella larvae FDI was observed in rosemary extract and the lowest amount of ECI, RGR and AD was related to eucalyptus extract. Therefore, these botanical extracts can be used to control these two important stored pests.
Three New Records of Gall Midges (Diptera: Cecidomyiidae) from Türkiye
Authors: TATAROĞLU Musa , KATILMIŞ Yusuf , SKUHRAVÁ Marcela
Published: December 2024

Three new records for the Turkish gall midges (Diptera: Cecidomyiidae) fauna were obtained for the first time from the seeds of Salvia sclarea L. collected during a field study in Denizli province, Türkiye. These new records are as follows: Arthrocnodax salviae Fedotova, 1995, Dasineura salviae (Kieffer, 1909) and Lasioptera salviae Schiner, 1868. The locations of the determined species in Türkiye, their world distribution and host plant data are provided.
Edosa truncatula Yang, Wang Li, 2014 (Tineoidea: Tineidae), a New Record to India
Authors: AHMAD Jalil , JOSHI Rahul , MOLLAH Kaiyum Baskh
Published: December 2024

In this study, we report Edosa truncatula Yang, Wang & Li, 2014 (Tineidae: Tineoidea) for the first time from India. Diagnosis, images of habitus and male genitalia are provided.
New and Little-Known Species of Ichneumonidae (Hymenoptera) for the Iranian Fauna
Authors: KOLAROV Janko , GADALLAH Neveen S. , GHAHARI Hassan , JUSSILA Reijo
Published: December 2024

This paper deals with faunistic surveys on Ichneumonidae (Hymenoptera) of Iran. In total, 18 species in eight subfamilies are recorded as new for the fauna of the country: Anomaloninae (one species), Banchinae (three species), Campopleginae (three species), Ctenopelmatinae (two species), Metopiinae (one species), Orthocentrinae (three species), Phygadeuontinae (two species), and Tryphoninae (three species).
First record of Hydropsyche cornuta Martynov, 1909 (Trichoptera, Hydropsychidae) from Iran
Authors: IBRAHIMI Halil , MOHAMMADI Habibollah , GHADERI Edris , KARIMIAN Erfan
Published: December 2024

Caddisfly sampling conducted during July 2021 from the Shalmash Waterfall in the West Azerbaijan Province of Iran, revealed the first record of Hydropsyche cornuta Martynov, 1909 for Iran. Previously this species had been known from several localities in Türkiye and few localities in Georgia, Lebanon and Syria. The morphology of male genitalia in the collected specimens from Iran corresponds to the described species. This discovery increases considerably the known areal of Hydropsyche cornuta and contributes to the knowledge of the Iranian Hydropsychidae. Shalmash Waterfall from where the new record is found is otherwise known for exceptional composition of aquatic insect fauna, including rare and endemic species.
PENGEMBANGAN VIDEO PEMBELAJARAN MENGGUNAKAN KINEMASTER APLICATION PADA KURIKULUM MERDEKA UNTUK KELAS IV SD
Authors: Estuhono Estuhono , Sapitri Sindi
Published: December 2024

The background of this research is the low learning outcomes of students in class IV SD, especially in science subjects, which is caused by the teacher not having teaching materials such as learning videos so that the learning process only takes place using the teacher's book and student's book. The purpose of this research is to produce learning video media that is valid, practical and effective. This research is a development research using the ADDIE model. This research was conducted in several stages, namely Analyze, Design, Development, Implementation, Evaluation. The results of validation research by three validators have an average score of 87 with a very valid category. The results of research on the practicality of learning videos conducted by teachers and students in grade IV SD have an average score of 95.5 in the very practical category. The effectiveness results carried out by all fourth grade elementary school students obtained a passing percentage of 93.1 in the very effective category. So, the conclusion of this study is that the development of learning videos using the Kinemaster Application has valid, practical, and effective criteria.
PENGEMBANGAN FLIPBOOK DALAM PENGUATAN LITERASI DIGITAL PADA MATERI IPS KELAS VII MTs
Authors: Maharani Silfi Ajeng , Pebri Setiani Puspita
Published: December 2024

The limited understanding of students in studying social studies causes very minimal learning media used by teachers. This leads to students becoming disinterested and failing to grasp the content during the learning process. The objective of this study is to enhance the digital literacy of students at Mts. The developed flipbook learning tool is designed for seventh-grade social studies, focusing on the introduction of Hinduism and Buddhism into Indonesia. This research adopts the Research and Development (R&D) approach, encompassing five stages: 1) Analysis, 2) Design, 3) Development, 4) Implementation, and 5) Evaluation. Data collection involved questionnaire assessments conducted by media and subject matter experts, along with small-scale group trials at MTS Mafatihul Huda in Madiredo village, Pujon subdistrict. The outcome of this development effort is a digital flipbook learning tool tailored for studying the entry of Hinduism and Buddhism into Indonesia within the social studies curriculum. The findings from the validation research by media experts indicated a feasibility rate of 79%, deemed acceptable. Similarly, material experts assessed the media with a 96% feasibility rate, considering it highly suitable. During small group testing, student assessments yielded a 94% feasibility rate, affirming the media's strong suitability. Consequently, based on these outcomes regarding the digital flipbook media used in teaching Social Sciences, specifically on the topic of The Entry of Hinduism and Buddhism to Indonesia in class VII, it is evident that the material is highly appropriate for application as a learning tool.
PERSEPSI MAHASISWA CALON GURU SEBAGAI PELAKU USAHA DALAM PENDIDIKAN KEWIRAUSAHAAN DI PERGURUAN TINGGI
Authors: Angga Rini Titis , Syarifah Putri Zahirotus , Hanisvana Dinik , Anggun Luqmana Annisa
Published: December 2024

Edupreneurship in higher education is aimed at introducing and developing student entrepreneurship. This research explored student teachers' perceptions of business behaviour in implementing edupreneurship. The study uses quantitative descriptive methods by extracting data through questionnaires and supporting documentation. This research began with a literature review, which was used as a basis for preparing research instruments for data mining, which was then continued in the final stage for data processing and concluding. The research results show prospective teacher students have a good perception (84.5%) of business interests, persistence and fighting power, business strategies, and their profession as entrepreneurial teachers or teacherpreneurs. This good perception is believed to provide positive affirmation to support better business behaviour, especially in the era of the Industrial Revolution. This perception can be a reference in developing entrepreneurship through entrepreneurship in higher education.
Opiniones sobre las mujeres ucranianas en el conflicto armado: la influencia del sexismo
Authors: Coronel Sandoval Rocío Agustina , Vera Gil Sara
Published: December 2024

Introducción. Tras las acciones militares por parte de Rusia, la población ucraniana se ha sumido en una profunda crisis humanitaria. Los conflictos armados se caracterizan por ser paternalistas, androcéntricos y por perpetuarse gracias al sexismo. En este contexto, el sexismo se exacerba y las mujeres y sus cuerpos son, una vez más,  objeto de opinión. Nuestra investigación se centra en estudiar la influencia del sexismo a la hora de explicar el papel de las ucranianas en el conflicto bélico actual, así como en determinar,  los niveles de sexismo y la influencia del género, la edad y el nivel educativo sobre el mismo. Metodología. Se llevó a cabo una investigación cuantitativa transversal de muestreo de conveniencia basado en la edad, contando con 146 participantes a quienes se aplicó el Inventario de Sexismo Ambivalente y un cuestionario basado en opiniones estereotípicas vertidas en redes sociales sobre las ucranianas. Resultados. Se encontraron diferencias en mujeres y en hombres, tanto en los niveles de sexismo como en la influencia de la edad y el nivel educativo sobre estos. En cuanto a la influencia del sexismo sobre la opinión del papel de las mujeres en la guerra de Ucrania, se obtuvo una fuerte relación positiva para ambos grupos. Por último, las puntuaciones medias obtenidas tanto por hombres como por mujeres en este mismo cuestionario fueron bajas, lo que refleja un desacuerdo generalizado con las afirmaciones estereotípicas. Discusión. Destacamos el impacto diferencial que el movimiento feminista ha tenido en mujeres y en hombres, así como la necesidad de continuar apostando por una educación con perspectiva de género que ayude a reducir los niveles de sexismo en los hombres, así como su implicación como aliados en la confrontación del mismo.
Relationship between Artificial Intelligence and Students’ Learning Strategies at Secondary Level
Authors: Kausar Fahd Naveed , Bahoo Rabia , Qaisara Rani , Waseem Muhammad
Published: December 2024

The objective of the study was to identify the level of AI and students’ learning strategies, and to find the relationship between AI and students’ learning strategies at secondary level. Artificial Intelligence is reshaping students' learning strategies by providing personalized content, immediate feedback, and data-driven insights that enhance engagement and comprehension. However, while AI promotes self-regulated learning and collaboration, it also requires careful balance to preserve essential human interaction in education. A quantitative and descriptive method is used in the study. The majority of participants were in the secondary school district of Sheikhupura. A questionnaire served as this study's primary research tool. The validity of the questionnaire was found through experts’ opinions and reliability through pilot testing. Descriptive and inferential statistics was used. The findings of the study revealed that there was highly significant relationship between AI and students’ learning strategies at secondary level.
UTILITAS PEMBERIAN EDUKASI PERILAKU HIDUP BERSIH DAN SEHAT (PHBS) BAGI KUALITAS PSIKOLOGIS ANAK BINAAN DI LEMBAGA PEMBINAAN KHUSUS ANAK KELAS II JAKARTA
Authors: Arzethy Putri Laura , Muhammad Ali , Anwar Umar
Published: December 2024

Perilaku hidup bersih dan sehat (PHBS) menjadi modal dasaar untuk meningkatkan kualitas kesehatan setiap individu. Lembaga Pembinaan Khusus Anak (LPKA) Kelas II Jakarta sebagai lembaga penempatan Anak yang Berkonflik dengan Hukum (ABH) tentunya penting untuk menanamkan pola hidup bersiah dan sehat (PHBS) selama Anak menjalani masa pembinaannya. Berdasarkan hasil observasi, wawancara dan kuesioner yang ditanyakan kepada 26 Anak Binaan kondisi kebersihan dan kesehatan Anak banyak terkendala oleh ketersediaan sarana dan prasarana saniitasi hygiene di LPKA, kondisi ini semakin diperburuk oleh kondisi pemahaman Anak tentang perilaku Hidup Bersih dan Sehat (PHBS) hal inilah yang berdampak kepada kualitas kesehatan psikologis Anak. Selain hal tersebut, Anak Binaan masih kurang memahami sepenuhnya arti penting dari Perilaku Hidup Bersih dan Sehat (PHBS) itu sendiri. Kualitas kesehatan psikologis Anak berdampak kepada perilaku Anak yang cenderung membatasi aktivitas kebersihannya dan Anak malas untuk menjaga kebersihan diri dan lingkungan sekitar. Hal ini menyebabkan Anak Binaan rentan terjangkit penyakit kulit, seperti Rabi atau Skabies. Metode yang digunakan Taruna dalam pelaksanaan praktikum pengabdian ini adalah Metode Community Development dalam membantu Lembaga Pembinaan Khusus Anak Kelas II Jakarta yang bertujuan untuk mencapai peningkatan penerapan Perilaku Hidup Bersih dan Sehat (PHBS) dengan menggunakan teknik kolaborasi dan sosialisasi atau penyuluhan, yaitu Taruna bersama dengan Lembaga Pembinaan Khusus Anak Kelas II Jakarta berkolaborasi bersama melakukan kegiatan dengan teknik sosialisasi atau penyuluhan guna meningkatkan kesadaran dan motivasi Anak Binaan dalam menerapkan Perilaku Hidup Bersih dan Sehat (PHBS) meskipun ditengah keterbatasan. Di akhir praktikum, terdapat peningkatan kesadaran dan aktivitas personal hygiene oleh Anak Binaan dalam menerapkan Perilaku Hidup Bersih dan Sehat (PHBS) selama di Lembaga Pembinaan Khusus Anak Kelas II Jakarta.
Griseofulvin Induced Stevens Johnson Syndrome (SJS). A Rare Case Report from District Headquarters Hospital, Chittoor, AP.
Authors: B Srinivasa , Ramyakrishna M. L. , P Madhav , V Sudharshan
Published: December 2024

Drug induced adverse drug reactions and events are quite common nowadays. Among those stevens-johnson syndrome (SJS) is one of the rare Severe Cutaneous Adverse Drug Reaction (SCAR) which is characterized by typical peeling of skin, mucous membrane and epidermal detachment. The incidence of Griseofulvin induced Stevens-Johnson syndrome is less than 1%. Here the patient initially went to local doctor for complaints suggesting fungal dermatitis like diffuse itching following which she was started on Tab Griseofulvin 500mg BD for 5 days. The next day she came to district govt. hospital with complaints of typical peeled of lesions and pain over face, arms, trunk and peritoneal area for which topical steroid and oral corticosteroid was advised for 2 weeks with tapered doses in between after stopping Tab Griseofulvin was advised by the treating doctor. Later Histopathological examination of the skin sample was performed. which revealed the findings of SJS. The causal relationship of tab griseofulvin with SJS as per ALDEN Algorithm in one of the standard Euro SCAR study was found to be certain. The causality assessment score for this event SJS was found to be 7 as per naranjo’s ADR probability scale, henceforth the causal relationship with ADR is found to be certain . Treating physicians especially dermatologists must be more aware and vigilant before prescribing and advising Griseofulvin for any fungal diseases by doing regular follow-up of patients if advised and assessment of early diagnosis of these similar reactions could benefit the society by preventing the occurrences of SJS in future.
Study of Unstimulated Salivary Calcium and Viscosity in Normal Adults
Authors: Barakzai Muhiba , Dawlaty Brishna
Published: December 2024

Background: Saliva is a unique biological fluid produced by different salivary glands. Human saliva is usually supersaturated with calcium that is one of the compositions of dental enamel. Viscosity is a rheological property of complex salivary fluid, which is related to its glycoprotein content. Methods: this is a cross sectional study conducted on 250 volunteers. Calcium was calculated using Arsenazo III reagent in semi auto-analyzer Microlab 300. and Viscosity was measured by Ostwald’s pipette. All data were analyzed in SPSS version 26. Mann Whitney U test was used for comparison of variables. Results: in this study among 250 volunteers there were165 (66%) female and 85 (34%) male and 95 (57.5%) women and 70 (42.5%) men were between 18-30 years old while 28 (32.9%) women and 57 (67.1%) men were between 31-65 years old. Calcium significantly increased after age 30 years in female than males, but the viscosity has not changed significantly in both age category. Women who are under 30 years old have a higher level of viscosity in the 18-30 years old, than that of men, but there is no difference in calcium. There were no significant change between calcium and viscosity among females and males and two age groups. Conclusion: it can be concluded that female’s salivary calcium is significantly increased than men and viscosity was higher in women after the age 30 years that is suggestive of more caries risk in females than males.
Sistem Pendukung Pengambilan Keputusan Pemilihan Objek Wisata Menggunakan Metode TOPSIS Studi Kasus Kabupaten Bengkayang
Authors: Redina anjelina Nathania , Vika  , Melindaria  , Sari Lili Lerian , Indramayu  , Leopaldo Martino Rios  , Noviyanti. P
Published: December 2024

Sistem pendukung keputusan telah menjadi bagian penting dalam mengoptimalkan proses pengambilan keputusan di berbagai bidang, seperti pemilihan objek wisata. Pemilihan tempat wisata yang tepat sangat penting untuk meningkatkan daya tarik suatu destinasi dan memenuhi kebutuhan pengunjung. Dalam konteks ini menggunakan metode TOPSIS (teknik penentuan prioritas berdasarkan kemiripan dengan solusi ideal) digunakan sebagai pendekatan untuk mengatasi kompleksitas dan   berbagai   kriteria   dalam   pengambilan   keputusan. Sistem Pendukung   Pengambilan   Keputusan yang diusulkan menggunakan metodologi TOPSIS untuk mengklasifikasikan dan mengevaluasi atraksi wisata alternatif berdasarkan serangkaian kriteria yang relevan. Kriteria tersebut dapat mencakup aspek-aspek seperti keindahan alam, fasilitas, aksesibilitas, kelestarian lingkungan, dan faktor ekonomi. Masing-masing kriteria diberi bobot berdasarkan kepentingannya dan diberi peringkat dengan mempertimbangkan kedekatan relatifnya dengan objek wisata serta solusi ideal positif dan negatif. Keunggulan utama sistem ini antara lain mampu menangani kompleksitas beberapa kriteria, mampu menyesuaikan bobot kriteria secara fleksibel sesuai preferensi pengguna, serta memberikan solusi yang lebih obyektif dan terukur dalam proses pengambilan keputusan. Pedoman berharga  bagi  pemangku  kepentingan  dalam  menyusun  strategi  promosi, pengelolaan dan pengembangan daya tarik wisata.
Medicinal plants traditionally used by the rural Kimalalu people in the municipality of Songo (Uíge province), Northern Angola
Authors: Mawunu Monizi , Malungo Afonso David , Cuca Afonso Lukebano , Luyeye Lukoki , Ndiku Luyindula , Ngbolua Koto-Te-Nyiwa
Published: December 2024

Herbal medicine is an important age-old tradition in Angola and forms part of the socio-cultural heritage of both the rural and urban population. In Kimalalu (northern Angola), phytotherapy continues to be used in the treatment of human illnesses, because of its low cost, accessibility, availability and acceptability. The aim of this study was to document the medicinal plants used to treat human illnesses in Kimalalu. Data were collected randomly from informants through semi-structured interviews and field observations. Ethnobotanical indices such as the relative frequency of citations were calculated. A total of 72 medicinal plant species beloning to 35 botanical families used for the treatment of 59 human diseases have been documented. The most abundant taxa were from the Fabaceae family, with 8 species (11.3%), and treated 17 human diseases. The leaves (62.5%) are the main plant organs used in the galinic preparation. Shrubs (31%) are the greatest life forms of documented plants. Decoction (50%) and oral intake (56.21) are the dominant used methods of preparation and administration, respectively. The most frequently cited illnesses were low haemoglobin (anaemia), followed by yellow fever, stomach ache, cough, typhoid fever, diarrhoea and malaria. Kimalalu is home to a wide variety of medicinal plants. It is therefore necessary to put in place policies and practices to conserve medicinal plants and the traditional knowledge associated with them. Local communities must be involved in the conservation and management of plant resources and their indigenous knowledge.
Marine spatial planning and best siting practices to achieve an ecosystem approach to aquaculture in the United States
Authors: Morris Jr James A , Wickliffe Lisa C , Theuerkauf Seth J , Shamaskin Andrew C , Jossart Jonathan , Randall Alyssa L , Froehlich Halley E , Riley Kenneth L
Published: December 2024

Marine aquaculture, defined here as aquaculture that takes place in coastal, nearshore, and offshore environments, has great potential for sustainable development in the United States. While the United States’ exclusive economic zone (EEZ) supports many ocean uses and socio-ecological systems, an ecosystem siting and management approach is imperative for aquaculture to develop sustainably. An ecosystem approach to aquaculture (EAA) is a broadly recognized strategy for developing aquaculture with minimal disruption to other ocean uses and environmental attributes. An ecosystem is defined here as the totality of environmental and human dimensions in which an aquaculture operation can interact. The United States can achieve an EAA by adhering to a suite of marine spatial planning techniques that are adaptive to scale, carrying capacity, and stakeholder preferences. In this paper, we discuss how the United States can better utilize marine spatial planning protocols to develop an EAA and grow the aquaculture industry with optimal efficacy. Ultimately, this paper is intended to serve as a blueprint for implementing an EAA for marine aquaculture in the United States. We first review the state of marine aquaculture within the United States, including state and federal regulatory frameworks and then discuss the principles of EAA and tools of marine spatial planning, including analyses that are pertinent to the scale of planning and for assessing carrying capacity. We conclude with a discussion on how marine spatial planning can lead to the successful implementation of an EAA.
Analisis Implementasi Konsep Creating Shared Value dalam Komunikasi CSR PT. Bank Rakyat Indonesia
Authors: Muhammad Luthfi Afdhal  , Iman Mukhroman  , Ikhsan Ahmad
Published: December 2024

Penelitian ini bertujuan untuk mendeskripsikan implementasi konsep Creating Shared Value (CSV) dalam upaya komunikasi CSR oleh PT Bank Rakyat Indonesia dalam Program TJSL BRI Peduli. Penelitian ini menggunakan pendekatan kualitatif dan lebih berfokus pada pemahaman terhadap proses dan dampak yang dihasilkan dari implementasi CSR). Subjek dalam penelitian ini adalah individu-individu yang memenuhi kriteria tersebut. Mereka adalah individu-individu yang terlibat dalam program "Wirausaha Muda BRIliant" PT. Bank Rakyat Indonesia, khususnya dari bagian Public Relations yang bertanggung jawab dalam pelaksanaan program ini. Dalam penelitian ini, peneliti memilih untuk menggunakan metode pengumpulan data berupa wawancara mendalam (intensive/depth interview). Selain menggunakan wawancara mendalam, peneliti juga menggunakan teknik observasi dalam penelitian ini. Temuan Menunjukkan bahwa PT. Bank Rakyat Indonesia Secara Aktif Mendorong Perluasan Usaha Mikro, Kecil, dan Menengah (UMKM) di Seluruh Indonesia. Hal ini dicapai, sebagian, melalui program wirausaha muda berprestasi (PMB), salah satu dari berbagai inisiatif yang bertujuan untuk meningkatkan kualitas pelaku usaha. Implementasi CSV dalam CSR pada program TJSL BRI Peduli telah menerapkan konsep keberlanjutan pada setiap usaha UMKM. Hal ini menyebabkan UMKM yang mengikuti kegiatan tersebut dapat merasakan dampak peningkatan usahanya.
Evaluación del Modelo Didáctico de Consultoría en el Aula: Estrategias para Mejorar el Aprendizaje Activo
Authors: Díaz Mendoza Raúl Francisco
Published: December 2024

El presente trabajo sobre la experiencia didáctica denominada Clases Consultoría, tiene como propósito profesional contribuir al desarrollo de la investigación, así como, exponer ante los lectores la sistematización reflexionada y, teóricamente, referenciada de una alternativa docente innovadora dirigida a la optimización del aprendizaje educativo de los estudiantes, sin importar sustantivamente, el nivel educacional que estén cursando. Las clases consultoría pueden ser utilizadas con modalidades presenciales, semipresenciales y a distancia, debido a que empoderan, para el autoestudio, la funcionalidad y la significatividad del aprendizaje educativo en comunidades de aprendizaje, tanto de los estudiantes como de los profesores consultores. La propuesta no busca disminuirle la autoridad al docente y transferírsela a los estudiantes, por el contrario, propone empoderar a ambos para dar el salto de calidad hacia la mejora continua y simultánea de profesores y alumnos.
RNA Devices for Therapeutic Applications: Progress, Challenges and Future Perspective
Authors: Dwivedi Vibha , Yun-Xing Wang
Published: December 2024

Review
RNA Devices for Therapeutic Applications: Progress, Challenges and Future Perspective

Vibha Dwivedi * and Yun-Xing Wang

Protein-Nucleic Acid Interaction Section, Center for Structural Biology, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA
* Correspondence: vibha.dwivedi@nih.gov

Received: 10 October 2024 2024; Revised: 21 October 2024; Accepted: 30 October 2024; Published: 1 November 2024

Abstract: Advances in RNA structural biology and engineering have stimulated thinking of using engineered RNA devices for precision cell and gene therapy. The RNA devices provide distinct advantages over existing approaches. Riboswitches, the key element in RNA devices, are regulatory structural elements found within mRNA in all three kingdoms of life but mostly in bacteria to sense the concentrations of small molecule metabolites, pathway products, uncharged tRNA and elemental ions for regulation of gene expression. Because of non-immunogenicity and several other advantages, riboswitches are considered to be a promising tool that may have significant implications in medicine and health. This review will provide an overview on the structural studies of key motifs critical for RNA device functions and some of the pioneering works aimed at developing RNA based therapeutics for medicine.
Avaliação das práticas de manejo na agricultura familiar em lajeado: foco no uso de defensivos
Authors: Martins Mireli Bergmann , Pinho Renata Silva Canuto de , Martins Vinicius Bergmann , Ethur Luciana Zago , Neves Jonas Anderson Simões das
Published: December 2024

A produção na agricultura familiar é influenciada por várias práticas agrícolas e características regionais, refletindo a diversidade cultural e ambiental, como clima, localização, bens de consumo e o nível educacional dos agricultores. Um aspecto crítico é o uso de agroquímicos, cuja relevância é evidente nas contaminações que afetam produtores, consumidores e o meio ambiente, resultantes do uso inadequado desses produtos. Este estudo tem como objetivo analisar e caracterizar as práticas de manejo agrícola de unidades familiares que vendem seus produtos nas feiras da cidade de Lajeado. A pesquisa busca avaliar o uso de pesticidas agrícolas em produtos comercializados tanto pela agricultura familiar convencional quanto pela orgânica, aprofundando a compreensão das práticas agrícolas na região e fornecendo suporte para o desenvolvimento sustentável da agricultura familiar. Entrevistas semiestruturadas foram realizadas em dias de mercado, utilizando um questionário com 16 perguntas. Os resultados indicaram a importância da assistência técnica, que facilitou a adoção de práticas adequadas de manejo de pesticidas, como o uso de Equipamentos de Proteção Individual (EPIs), a aplicação em momentos apropriados e o descarte correto das embalagens. O uso de agentes biológicos, como a mistura de calda bordalesa e leite cru, também foi observado em ambas as modalidades agrícolas. Os agricultores demonstraram otimismo em relação às suas colheitas e clareza nas informações recebidas dos técnicos. Conclui-se que este artigo fornece uma análise das práticas agrícolas na região, destacando a relevância da agricultura familiar para a disponibilidade de alimentos saudáveis e sustentáveis, contribuindo para o fortalecimento das comunidades locais.
Implicações da Educação Profissional e Tecnológica (EPT) na “reintegração”, “recuperação”, “readaptação”, “reinserção”, “reeducação” e “reabilitação” dos “sentenciados”
Authors: Albuquerque Junior Ailton Batista de , Araújo Ana Cláudia Uchoa , Rocha Sinara Socorro Duarte , Costa Rodrigo Carvalho Souza , Azevedo Luiz Felipe Araújo , Lima Marcos Antonio Rocha de , Araújo Naftali Teixeira de , Carvalho Michele Lemos de Oliveira Sousa , Barroso Maria Daliane Ferreira , Freitas Silvana Ramos de Assis , Barros Gilson da Silva , Costa Aline Lima Soares da , Rocha Chrystiane Viegas , Barros Renata de Oliveira Goes , Guerra Lorena de Fátima Coelho
Published: December 2024

O presente estudo tem como objetivo discutir a pertinência da Educação Profissional e Tecnológica (EPT) na ressocialização dos apenados como alternativa viável à crise do sistema carcerário brasileiro. Com fulcro no exposto, demarcamos que o sistema prisional para além de suas finalidades básicas, deveria servir como órgão ressocializador, haja vista que a reintegração penal  é um pilar constitucional para a reinserção dos egressos na sociedade contemporânea. Concernentemente ao desenho metodológico, aplicamos uma pesquisa de abordagem qualitativa, com fulcro na pesquisa bibliográfica e exploratória. Daí, inferimos haver incapacidade de ressocialização dos apenados pela prisão nos moldes atuais, em virtude da precariedade das políticas públicas sociais no seio de espaços que parecem com filmes de intenso terror. Porquanto,  sustentamos a pertinência e a urgência no fortalecimento da política de educação para o sistema prisional, por intermédio de investimentos em ações de fomento à  reinserção do egresso do cárcere,  com vista que as implicações pedagógicas e cognitivas no âmbito dos processos de cidadania são comprovadamente positivos para a formação e encaminhamento de qualquer ser humano.
Roadmap to implementation and management of innovation in the brazilian civil construction industry
Authors: Pires Vinícius Rodrigues Silva , Simões Eliane Antonio , Cirani Claudia Brito Silva , Ribeiro Rosinei Batista
Published: December 2024

This study aims to develop a roadmap to be used by a small enterprise that operates in the civil construction sector for the implementation and management of innovation. Bibliometrics were used for the construction of the theoretical framework. The Design Science Research was used to create the proposed artifact and a single case study was used for roadmap validation, indicating practical propositions for companies of the same sector and size as well as theoretical suggestions for future studies. The proposed roadmap was developed from the analysis of the theoretical foundation, mainly in studies that defined similar artifacts. The application of this roadmap in a case study allowed verifying its potential for implementation and management of innovations in the enterprise studied. The roadmapping process generated a roadmap with organized and clear information for customers, suppliers, and employees of the enterprise. It also assisted in the research and selection of innovations to be implemented. Participants showed integration with the proposal and with the process and this integration remained even after the conclusion of the study. The proposed roadmap facilitated the implementation and management of innovations in terms of products, processes, organization, and marketing.
ANALYSIS OF THE POTENTIAL IMPACT OF SOCIAL MEDIA USAGE ON THE MENTAL HEALTH OF ADOLESCENTS
Authors: RIAZ M , RIAZ L
Published: December 2024

The increasing prevalence of social media usage among adolescents has raised concerns about its potential impact on mental health. The interplay between social connectedness, self-esteem, and mental health requires further exploration to understand the mediatObjective:ing mechanisms involved.  To assess the association between social media usage and adolescents’ mental health and the impact of social connectedness and self-esteem on this association. Methods: A cross-sectional study was conducted in the Department of Pediatrics and Department of Psychiatry of DHQ, Narowal from October 2022 to October 2024. A total of 500 adolescents aged from 12 to 15 years attending the hospital departments were included in the study. Data was collected by a 25-item self-completion Strengths and Difficulties questionnaire to assess mental disorders in the participants. To evaluate social media usage, participants were about time spent on its usage. Self-esteem and social interaction were also assessed as mediators. Results: In unadjusted analysis, participants with more active hours had poor mental health with a one-point increase in SDQ score with every increase in socialization (95% CI: 0.19-1.68). Unadjusted analysis showed that more hours on social media led to low self-esteem (p=0.01) and, hence poor mental health (p<0.001). The Monte Carlo test was also significant for an indirect association between self-esteem and mental health (p=0.02) with a 70% impact of social media mediated by self-esteem. More hours on social media were related to reduced happiness with friends (p=0.01) but this did not lead to poor mental health (p=0.58). Conclusion: A higher number of hours spent on social media leads to mental health problems in adolescents in the long term. Additionally, low self-esteem due to social comparison by the use of social media is also an indirect mediator of poor mental health.
Anfiteatro Romano na Piazza Sant’Oronzo
Authors: Bordin Marcelo
Published: December 2024

Datado do século II, o anfiteatro romano foi descoberto na primeira metade do século XX. Está situado na principal praça da cidade de Lecce, no sul da Itália. A cidade é a principal da região de Salento. A região foi habitada inicialmente pelos messápios e depois foi parte dos imérios romano e bizantino. A arquitetura é predominantemente barroca em virtude da ocupação normanda, transformando-se em uma importante rota comercial com importantes portos. A região também foi ponto de partida de soldados para as cruzadas. A cidade de Brindisi, a 30 quilômetros de Lecce foi um importante hospital onde eram tratados os feridos que conseguiam retornar. A foto foi capturada no final do verão do ano de 2022, durante o estágio de Pós-Doutorado no Centro Di Ricerca EuroAmericano Sulle Politiche Costituzionali (CEDEAUM), da Università Del Salento.
O ESPAÇO SAGRADO NA FORMAÇÃO DE QUATRO PONTES-PR: entre o imaginário sagrado e as representações sociais
Authors: Feldhaus Fabiano , Deimling Juçara
Published: December 2024

Diversos aspectos do simbólico-religioso moldam a vida e a cultura de muitas comunidades e por esta razão queremos apontar para uma reflexão sobre os sentidos representativos que esses aspectos têm dentro delas e dentro do espaço sagrado da comunidade de Quatro Pontes no extremo oeste do Paraná. Quando buscamos entender o fenômeno religioso é importante assinalar que está se utilizando o “imaginário” e as representações sociais como elementos para a compreensão das relações sociais e isso envolve entender como as imagens mentais, ideias e símbolos compartilhados influenciam e são influenciados pelas percepções e interpretações que as pessoas têm do mundo ao seu redor. A Igreja historicamente desempenhou um papel significativo na migração e na formação de comunidades em muitas regiões ao redor do mundo. Portanto, é uma investigação que busca perceber a participação e a influência da Igreja na migração e constituição da comunidade de Quatro Pontes, cujas referências estão respaldadas numa expressiva cultura religiosa. Desta forma busca-se uma investigação caracterizada pela geografia da religião, ao perceber e analisar a atuação dos colonos fiéis à cristandade e a atuação da Igreja enquanto uma instituição fomentadora de colonização e de relações migratórias caracterizadas por representações culturais em um determinado espaço geográfico.
Pengaruh Idealisme, Machiavellian, Tingkat Pengetahuan Etika Dan Love Of Money Terhadap Persepsi Mahasiswa Akuntansi Mengenai Krisis Etika Akuntan
Authors: Putri Asri Azmi , Pentiana Destia , Kurniawan Umarudin
Published: December 2024

Penelitian ini bertujuan untuk mengetahui pengaruh idealisme, machavellian, tingkat pengetahuan etika dan love of money terhadap persepsi mahasiswa akuntansi mengenai krisis etika akuntan. Variabel independen dalam penelitian ini adalah idealisme, machvellian, tingkat pengetahuan etika dan love of money. Sedangkan variabel dependen dalam penelitian ini adalah persepsi mahasiswa akuntansi mengenai krisis etika akuntan. Penelitian ini diuji dengan menggunakan alat uji SPSS versi 26 dengan alat analisis regresi linier bergana. Metode pengambilan sampel dengan menggunakan metode purposive sampling dan besar sampel menggunakan rumus slovin dengan kepercayaan 90% dan angka e 10%. Maka sampel dalam penelitian ini berjumlah 105 responden. Hasil penelitian ini menunjukkan bahwa idealisme tidak berpengaruh terhadap persepsi mahasiswa mengenai krisis etika akuntan. Sedangkan machiavellian dan love of money berpengaruh positif terhadap persepsi mahasiswa mengenai krisis etika akuntan. Kemudian tingkat pengetahuan etika berpengaruh negatif terhadap persepsi mahasiswa mengenai krisis etika akuntan. Akan tetapi, secara simultan variabel idealisme, machiavellian, tingkat pengetahuan etika dan love of money berpengaruh terhadap persepsi mahasiswa mengenai krisis etika akuntan.
Realities and polyamorous identities in non-monogamy
Authors: Danut Simion
Published: December 2024

The realities and identities within polyamorous relationships in the non-monogamy sphere reflect a wide diversity and complexity in relational dynamics. Polyamory, as a form of non-monogamous relationship, is based on the idea that individuals can have multiple romantic or intimate connections at once, with the consent and agreement of all involved. These relationships can vary considerably in structure and dynamics, sometimes imposing specific challenges and pressures in communication and managing emotions. Managing multiple relationships as well as the different expectations of partners requires open, honest communication and a deep understanding of each individual's needs. This paper attempts to analyze how those in polyamorous relationships construct and negotiate their polyamorous identities in relation to the dominant discourses of monogamy, sexuality, and gender. It also seeks to identify how polyamorous individuals manage their multiple relationships, cope with stigma and discrimination, and seek support and community.
Consent as a specific challenges in different types of relationships
Authors: Danut Simion
Published: December 2024

Consent is a fundamental aspect of any relationship, whether monogamous or non-monogamous. However, different types of relationships may present specific challenges to obtaining and maintaining consent. In monogamous relationships, based on the assumption that two partners are exclusive and faithful to each other, clarity and open communication about desires, boundaries, and agreements are crucial to ensuring consent. It refers to mutual agreement and respect for the partner's wishes regarding intimacy and sexual interactions. However, this assumption may not always be clear or agreed upon by both parties. In non-monogamous relationships, operating on the premise that one or both partners may have multiple romantic or sexual relationships with other people, consent becomes even more complex because it involves multiple people and varied dynamics. Open communication is essential to clarify and reinforce the agreements and wishes of all parties involved. Respect for the boundaries and needs of each individual becomes fundamental in ensuring consent in such relationships. Regardless of the type of relationship, consent requires transparency, mutual respect, and clear and explicit agreement between all involved. It is an ongoing process that requires open and honest communication to ensure mutual understanding and respect.
Organizational incivility: patterns and profiles at the workplace
Authors: Ceban-Muzicantu Catalina
Published: December 2024

Organizational incivility is a type of behavior frequently encountered in the organizational environment. Even if it has low intensity and is vaguely perceptible, recent studies show that these manifestations can be contagious and over time can become part of the organizational culture. It typically manifests through behaviors such as taking credit for someone else's work, unpleasant emails, and ambiguous compliments, which cumulatively affect employees' well-being at work. Distinct characteristics of the target (victim), the provocateur, and the witness were noted, considering criteria such as position in the organizational hierarchy, certain personality traits, and behavioral reactions.
Recent progress in camel research
Authors: Seida Ashraf , Hassan Marwa , Abdulkarim Abdulrahman , Hassan Elham
Published: December 2024

Background:
Camelids play an important role in the preservation of ecosystems, biodiversity, food security, economic growth, adaptation to climate change, and cultural and social aspects. Therefore, the United Nations (UN) has named 2024 the International Year of Camelids (IYC).

Aim:
This study aimed to assess the recent progress in camel research and its citation effect as shown in the Scopus database in the IYC.

Methods:
On March 17, 2024, a literature search was done to discover papers indexed in Scopus® using the search terms "camel", "camelids", and "Camelus dromedarius". Automatic and manual screening processes were used.

Results:
Between 1850 and 2024, a total of 15,844 camelid-related papers were published. Approximately 30% of these documents were released within the previous five years (2019-2023). Camel research was included into 28 scientific topics. The top five topics were agricultural and biological sciences, medicine, veterinary science, biochemistry, genetics and molecular biology, immunology, and microbiology. The top five authors in camel research were Faye B, Wernery U, Muyldermans S, Kinne J, and Sahani MS. The top five camel research contributors among 159 academic institutions were from King Saud University, King Faisal University, ICAR-National Research Centre on Camel, Bikane, Cairo University, and United Arab Emirates University. Out of 152 nations active in camel research, the top five were the United States, Saudi Arabia, Egypt, Undefined, and India. The top five languages were English, French, Chinese, Russian, and German. The camel research was financed by 158 sponsors, with the top five being undefined, the National Natural Science Foundation of China, the Deanship of Scientific Research, King Saud University, the National Institutes of Health, and the National Science Foundation. Camel papers have been published under 161 source titles. The top five sources were: Journal of Camel Practice and Research, Tropical Animal Health and Production, Indian Journal of Animal Sciences, Veterinary Parasitology, and Emirates Journal of Food and Agriculture.

Conclusion:
Although camelids are understudied in scientific studies, there has been a promising increase in camel research over the past five years. Furthermore, the IYC may give a unique opportunity to assist scientific research, particularly in low-income countries with large camelid populations.
Possible relationship between pre-pregnancy maternal body mass index and offspring hippocampus: An experimental study in albino Wistar rat
Authors: Greash Zahraa , Elmajdoub Layla , Fayad Eman , Almaaty Ali
Published: December 2024

Background:
Cognitive impairment and attention deficit disorder have been on the rise among generations in recent times. A significant portion of the brain involved in learning and cognition is the hippocampus. Its development begins in utero till weaning. The mother's body mass index (BMI) before pregnancy indicates her health; however, little data links maternal BMI before pregnancy to fetal hippocampal health outcomes.

Aim:
The study aimed to estimate the extent to which pre-pregnancy maternal body mass index (BMI) relates to their offspring brain status, and thus to what extent to this stage of life may be an opportunity for mental and cognitive development.

Methods:
Thirty-six naive female albino rats (Rattus norvegicus) at 8 weeks of age with average weight 190-220g body weight were obtained and assigned to three experimental groups according to their body mass index into; under-, over- and normal weight. Following one week of habituation, all females were allowed to mate (3 female/ 1 male). On postnatal day1, pups were randomly adjusted to 8/dam with equal gender ratio. On 15 day postpartum, all pups were sacrificed. Hippocampi were removed and processed for histological investigations, GFAP immunohistochemically and flow cytometric assessments of apoptosis. Measurements of cognitive brain were carried out.

Results:
The present findings manifested elevation in the inflammatory and apoptotic markers in the hippocampus of underweight mothers-offspring yielding a lower cognitive ability than overweight mothers-offspring compared to those whose mothers with normal weight before conception. The male offspring were more affected than female offspring especially those born to pre-pregnancy underweight mothers.

Conclusion:
The study concluded that there may be a connection between a mother's pre-pregnancy BMI and her offspring's cognitive capacities, which calls for more study to gain a deeper knowledge and to create interventions that target the physical health of the mother prior to pregnancy in order to enhance their offspring's health and cognitive outcomes.
Detection of the methicillin-resistant Staphylococcus aureus (MRSA) gene encoding mecA in nasal swabs of cats in Surabaya, Indonesia
Authors: Ramadhani Safira , Khairullah Aswin , Effendi Mustofa , Sukmanadi Mohammad , Tyasningsih Wiwiek , Millannia Saumi , Afnani Daniah , Moses Ikechukwu , Farizqi M , Kaben Sergius
Published: December 2024

Background:
The most susceptible group of people to spread methicillin-resistant Staphylococcus aureus (MRSA) among domestic cats is their owners' relatives.

Aim:
Considering the aforementioned, research at the Surabaya City Animal Hospital is necessary to determine whether the mecA gene may be detected in cat nasal swabs.

Methods:
Samples were taken using a sterile cotton swab, and the transport medium was buffered peptone water. Standard operating procedures in microbiology were then employed to identify the samples. Using five distinct antibiotic discs, the Kirby-Bauer diffusion method was used to determine the antibiotic resistance profile of S. aureus. All cefoxitin-resistant S. aureus isolates were tested for MRSA and then the mecA gene was detected.

Results:
Based on morphological culture features, Gram staining, and biochemical assays, 64 samples (64%) of the 100 isolated cat nose swab samples were positive for S. aureus, according to the results of the biochemical tests. The profile of antibiotic resistance developed from the results of the S. aureus resistance test to antibiotics revealed that five (7.81%) of the 64 S. aureus isolates were confirmed to be multidrug resistant. Out of the 6 MRSA isolates analyzed, the mecA gene was detected in 5 isolates.

Conclusion:
Based on the findings of this study, a thorough assessment of the impact of using antibiotics to prevent the spread of MRSA in veterinary hospitals on the general public's health is required in light of the detection of MRSA isolates bearing the mecA gene in the Surabaya veterinary hospital.