bluuebunny/crossref_metadata_2025 huggingface dataset:
Contenidos proyectivos y por qué se proyectan
Authors: Ubiarco Moya Juan Ricardo
Published: May 2024

Este artículo propone un acercamiento breve, pero completo, a la proyectividad de ciertos contenidos comunicados por los enunciados de los hablantes, rasgo utilizado desde diversas teorías lingüísticas y filosóficas para el estudio del significado. El texto presenta, primeramente, el origen y la definición del rasgo de proyectividad y la prueba diseñada para detectarlo. Después, se realiza un repaso por varios tipos de contenidos estudiados en relación con su proyectividad. Finalmente, se presenta y discute dos propuestas para unificar los contenidos proyectivos.
Disponibilidad léxica y exclusión social. Datos sociolingüísticos de la Ciudad de México
Authors: Montiel Pérez Dinorah Beatriz , Serrano Julio César
Published: May 2024

En este trabajo se analizan disfemismos socioeconómicos en el español de la Ciudad de México, en una red social de clase media. A través de una encuesta onomasiológica se obtuvieron 135 vocablos referentes a la exclusión social. Los resultados arrojan luz sobre el léxico de tres grupos de edad. El concepto de prototipicidad permitió distinguir la relación entre el vocabulario y los campos léxicos donde se enfoca la discriminación. El campo léxico de la exclusión social se subdividió en ocho campos. La investigación aporta al conocimiento del léxico de la discriminación en grupos sociales medios de la Ciudad de México y, metodológicamente, ofrece una alternativa para la obtención de léxico pasivo en los estudios de disponibilidad léxica.
Cambio aspectual en los tiempos Perfecto Simple y Compuesto del español mexicano (s. XVII - XXI)
Authors: Pérez Lezama Erika
Published: May 2024

El presente trabajo documenta y analiza a nivel diacrónico la conocida dupla de tiempos verbales de pasado en español: el Pretérito Perfecto Simple (PPS) y el Pretérito Perfecto Compuesto (PPC)en español mexicano durante los s. XVII, XIX y XXI. Uno de los cambios más relevantes que se advirtió fue la especialización de aspecto perfecto por parte PPC. Así, se determinó que este tiempo en los s. XVII y XIX expresaba dos contenidos aspectuales (perfecto y perfectivo) pero, después, en el s. XXI, el contenido perfectivo desapareció casi completamente en esta variedad. Como resultado de estas observaciones, se propone que el español de México manifiesta una dirección de cambio distinta a la planteada por Harris (1982) para el español de América.
Esther Hernández y Pedro Martín Butragueño (eds.). Las palabras como unidades lingüísticas. Consejo Superior de Investigaciones Científicas-El Colegio de México, 2020. España; 467 pp.
Authors: Carrera Guerrero Hugo
Published: May 2024

El concepto de "palabra" dentro de la teoría y la descripción lingüística es una de las categorías más complejas de asir, en principio, porque su presuposición y estatus dentro de los sistemas lingüísticos pueden ser definidos desde distintos niveles de análisis.
Marisela Colí­n Rodea (coord.). Escribe todas las palabras que vienen a tu mente... Léxico disponible y aprendizaje de lenguas. Escuela Nacional de Lenguas, Lingüística y Traducción, Universidad Nacional Autónoma de México, México, 2022; 180 pp.
Authors: Franco Trujillo Erik Daniel
Published: May 2024

Cuando se estudia una lengua extranjera es común reparar en que, una vez asimilado un número significativo de estructuras y reglas gramaticales, el siguiente gran desafío consiste en la apropiación de un vasto vocabulario para acelerar nuestra competencia comunicativa. A fin de cuentas, entre mayor sea el léxico que pueda manejarse con precisión y soltura, más fácil será desenvolverse en distintos contextos sociales, comprender textos de temas diversos y ampliar nuestros horizontes de interpretación.
Francisco Arellanes y Lilián Guerrero (eds.). Estudios lingüísticos y filológicos en lenguas indígenas mexicanas. Celebración de los 30 años del Seminario de Lenguas Indígenas. Instituto de Investigaciones Filológicas, Universidad Nacional Autónoma de México
Authors: Meléndez Guadarrama Lucero
Published: May 2024

Este volumen es una estupenda radiografía de los estudios lingüísticos y líneas de investigación que se desarrollan en la actualidad en el Seminario de Lenguas Indígenas (SELIN) del Instituto de Investigaciones Filológicas de la UNAM; contiene contribuciones tanto de los investigadores de tiempo completo del Seminario como de algunos investigadores que han colaborado temporalmente en dicho centro de investigación.
Cuestionario de Dominancia Lingüística en Sordos (CDLS)
Authors: Mendoza Elizabeth , Jackson-Maldonado Donna , Avecilla-Ramírez Gloria
Published: May 2024

Existen instrumentos para medir la dominancia lingüística en bilingües oyentes, pero pocos para bilingües Sordos. En México, no hay instrumentos que evalúen la proficiencia lingüística de Sordos señantes; por ello, las características lingüísticas de los Sordos señantes mexicanos han sido poco descritas. En esta investigación, se explican los cambios hechos para adaptar el Bilingual Language Profile (BLP) a la lengua de señas mexicana (LSM) y al español oral y escrito. El BLP ha sido adaptado a diferentes lenguas orales, pero a ninguna lengua visogestual. Así, se realizaron cambios léxicos, sintácticos y culturales; se aplicaron cambios en la forma de calificar para evaluar la proficiencia lingüística en tres pares lingüísticos: LSM-español escrito, LSM-español oral y español escrito-español oral, y se propone el nombre Cuestionario de Dominancia Lingüística en Sordos (CDLS).
Karina R. Araiza y Stephen A. Marlett. Conceptos de lingüística descriptiva. Un acercamiento a las lenguas del mundo. Instituto Lingüístico de Verano, México, 2021; 164 pp.
Authors: Buenrostro Cristina
Published: May 2024

El libro que se reseña consta de 164 páginas en las que se describe de una manera simple y amigable los principales conceptos de la lingüística descriptiva, esenciales para quien quiera incursionar en el mundo de la descripción de cualquier lengua del mundo. Resulta de gran utilidad tanto para estudiantes que se inician en el campo de la lingüística como para docentes que lo quieran usar de base para un curso de introducción a la lingüística. Uno de los grandes aciertos de esta obra son los ejemplos en diferentes lenguas, de las cuales se enfatiza que no se puede hablar de lenguas primitivas o simples, sino de diferentes sistemas gramaticales.
James Law, Sheena Reilly y Cristina McKean (eds.). Language Development: Individual Differences in a Social Context. Cambridge University Press, Cambridge, New York; 2022; 563 pp.
Authors: Ramos Garín Clara
Published: May 2024

Dentro de las múltiples y variadas opciones de publicaciones que existen en torno al interesante fenómeno de la adquisición y desarrollo de la lengua, el presente texto emerge como una respuesta original e innovadora que ofrece, a las personas interesadas en áreas como la lingüística, la psicolingüística y la educación, una serie de investigaciones recopiladas y editadas por Law, Reilly y McKean, bajo una perspectiva teórica actual que se utiliza mucho pero que pocos autores definen claramente: el interaccionismo.
Annick De Houwer. Bilingual Development in Childhood. Cambridge University Press, 2021; 85 pp.
Authors: Fascinetto-Zago Karina
Published: May 2024

La obra Bilingual Development in Childhood, escrita por Annick De Houwer, ofrece una visión integral de un tema clave para la lingüística y las ciencias del lenguaje: el desarrollo bilingüe temprano. De Houwer plantea tres situaciones de desarrollo bilingüe temprano: adquisición bilingüe de una primera lengua, adquisición temprana de una segunda lengua y adquisición de una segunda lengua. El propósito principal de la publicación es elucidar los distintos efectos que estas diferentes situaciones tienen sobre las trayectorias del desarrollo lingüístico temprano de los bilingües (p. 5). Y también es un objetivo examinar la naturaleza de estas situaciones en relación con la cantidad de habla dirigida al infante, las prácticas conversacionales parentales y los efectos de las actitudes lingüísticas (p. 6). Tras una amplia revisión bibliográfica, y pese a la gran variabilidad que se observa en cada caso estudiado, la autora logra formular algunas consideraciones generales de acuerdo con el propósito que persigue; y también brinda una reflexión sobre aspectos que se deben considerar con más detalle al investigar el desarrollo bilingüe durante los primeros años de vida.
Send more guns: Biden’s Fiscal Year 2024 budget plan for Africa
Authors: Volman Daniel
Published: May 2024

This paper examines US security policy toward Africa. It describes and analyses US security assistance to Africa and Biden’s security assistance budget request for Africa for Fiscal Year 2024. It also reports testimony of the commander of Africom at the hearings on the budget request held before the US House and US Senate Armed Services Committee in March 2023.
Hobsbawm on rebellion in the postcolony: the political economy of armed conflicts in Northern Nigeria
Authors: Ejiofor Promise Frank
Published: May 2024

Nigeria’s northwest geopolitical zone is increasingly bedevilled by banditry perpetrated, in part, by aggrieved pastoralists. Pastoralist participation in banditry has been characteristically analysed using theoretical frameworks that portend their violent activities – kidnapping, cattle raiding and murder – as ordinary crimes deriving from ungoverned spaces and socioeconomic deprivation. While such theoretical outlooks shed light on the nature of armed violence in the northwest, they have failed to assess how pastoralist banditry constitutes not so much an ordinary crime but a social crime – a form of resistance against social inequality that stems from the longstanding marginalisation of pastoralism and pastoralists in precolonial, colonial and postcolonial Nigeria. Inspired by the Marxist historian Eric Hobsbawm’s conception of social banditry, this article contends that pastoral banditry constitutes resistance to conjugated oppression axiomatic from the contradictions of the Nigerian political economy. Resolving the crisis of pastoral banditry in the region therefore requires attending to the marginality of pastoralists by curtailing abuses and providing public goods.
Review of Fault Diagnosis and Early Warning of Coal Mine Ventilator
Authors: Srujan kumar V
Published: May 2024

The fault diagnosis and early warning system for coal mine ventilators play a pivotal role in ensuring the safety and efficiency of underground coal mining operations. This review delves into the state-of-the-art techniques, methodologies, and advancements in fault diagnosis and early warning systems specifically tailored for coal mine ventilators. The review encompasses a comprehensive analysis of various approaches, including traditional methods, such as rule-based systems and expert systems, as well as modern techniques like machine learning algorithms, artificial intelligence, and data- driven models. It examines the challenges associated with fault diagnosis in coal mine ventilators, such as the complex and harsh operating environment, limited data availability, and the need for real-time monitoring. Furthermore, the review discusses the importance of early warning systems in mitigating potential hazards and preventing catastrophic incidents in coal mines. It explores the role of sensor technologies, data acquisition systems, and communication protocols in enabling timely detection and notification of abnormalities in ventilator performance
Propuesta interactiva para el desarrollo de las competencias digitales
Authors: Fernández Marín Miguel Ángel , Valladares González María Guadalupe , Alfonso Moreira Yaquelín
Published: May 2024

The objective of this work is to show a set of technological resources to promote virtual learning as part of university professional training. Moving from face-to-face to virtuality in education is one of the most relevant controversies today. Despite the fact that virtual environments and technology applied to different branches of science and culture are already a reality, the pandemic has led education professionals to redefine their functions and modes of action. The conception of virtual learning environments implies a change of worldview and thought with respect to social, cultural, family and personal life. The improvement of university professional digital skills in teachers and students is proposed from the use of programs for the development of interactive learning resources.
Meta-análisis sobre la educación multigrado en México: alcances, tendencias, oportunidad y vacíos
Authors: González Lira Ana Laura , Moreno Tapia Javier
Published: May 2024

This article provides a meta-analysis of the research trends identified in various academic works carried out in the context of multigrade schools in Mexico. Analysis tables are integrated that facilitate the interpretation of the thematic trends and the lines of research that are addressed in the works. The information presented allows us to recognize results and advances, identify elements that require attention in future research and generate guidelines that guide the course of new studies and the design of lines of action from the educational policy to meet the characteristics of schools of multigrade organization.
Constitucionalidad del procedimiento expedito en contravenciones contra la mujer o miembros del núcleo familiar
Authors: Sánchez Smith Antonio , Miño Morales Luis Alfonso , Sisalema Carrillo Ángel Oswaldo
Published: May 2024

Violence against women and members of their family nucleus from earlier stages is defined as a serious social problem at the international level. The Constitution of the Republic of Ecuador of 2008, highly guaranteeing rights, establishes expeditious procedures for the trial and punishment of crimes of domestic violence subject to the principle of procedural orality and summary proceedings. The object of investigation turned out to be the implementation of the punitive model in contraventions of violence against women or members of the family nucleus. A mixed research approach was used with a descriptive exploratory scope and the following methods were used: inductive, deductive, historical-logical and analysis-synthesis. The results are associated with the improvement of axis No 4 of the Council of the Judiciary: Strengthening of the Investigation and Punishment Mechanisms in cases of sexual violence against children, adolescents and women.
Producción diversificada de alimentos en patio y parcela para el autoconsumo familiar
Authors: Terry Espinosa Caridad , Hernández Castellanos Maritza , Almoguea Fernández Minerva , Hernández Calzadilla Reina Evelyn
Published: May 2024

Food security is when all people at all times have physical, social and economic access to sufficient, safe and nutritious food that meets their daily energy needs and food preferences to lead a healthy and active life. Family farming constitutes one of the first links in healthy eating, since it eliminates the use of agrochemicals that are harmful to health. The present study aimed to evaluate the diversified production of food in the yard and plot for family self-consumption with healthy and sustainable practices. It was developed in a family patio in the Palmira municipality in the period from March 2020 - June 2021, for which the biodiversity of plants in the patio and animal species present to diversify was diagnosed. An investigation of the no experimental type was carried out, using methods of the theoretical and empirical level. As a result, there was an increase in productions, an increase in biodiversity, economic, social and environmental improvement with the application of agricultural and sustainable practices in the family yard, which facilitated the availability of healthy and nutritious food.
Personality similarity in spouses related to marriage roles
Authors: Barton Keith
Published: May 2024

From an original sample of 93 married couples 71 couples were selected according to criteria which determined how similar they were to their spouses on several personality variables. Specifically 3 groups of people were defined: a similar group who resembled their spouses highly in personality, a Random group who were neither positively or negatively matched with respect to personality measures and an Opposite group who tended to be opposite to their spouses on the personality measures. For each of these 3 groups, and for husbands and wives separately, scores on several marriage dimensions were compared. It was found that for both husbands and wives the Similar personality groups tended to score higher on the marriage role factor of Male Dominance than did either the Random or Opposite groups. For the wives data only, the Similar group also scored higher than the Random or Opposite groups on the marital factors of 1) Sexual Gratification and 2) Togetherness and Role Sharing. Possible implications and explanations for these findings are discussed.
Clues to the preferences of therapy styles
Authors: Fenster C. Abraham , Wiedemann Carl F , Balkin Joseph
Published: May 2024

This study examined the relationship of personality variables to the choice of a psychotherapist. 119 subjects were shown films of three prominent therapists at work with the same patient. The subjects were asked to indicate which of the three they would select if they were to choose a therapist. The subjects were given a battery of psychological tests, and personality differences relating to the choice of therapist were examined. The results suggested that intelligence and authoritarianism are relevant variables, with more intelligent, less authoritarian subjects tending to choose the therapist (Albert Ellis) who has markedly rational, problem-solving approach. The lack of additional personality differences in the findings was interpreted in terms of the weaknesses of the psychtherapy analogue employed. It is probably necessary to asses real patients choosing real therapists.
Evidence for the 16PF primary and secondary factors
Authors: Bolton Brian
Published: May 2024

Brief reviews of the published factorial studies of the 16PF suggest that the evidence is divided regarding the existence of the 16 primary factors. There is considerable convergence at the secondary level, however. In the present investigation factor analyses of 128 items, 32 parcels, 16 scales, and 16 change scores derived from the 16PF-E using a heterogeneous sample of rehabilitation clients provided strong confirmation of the eight 16PF secondaries and, by implication, support for the existence of the 16 primaries. It is concluded that all available evidence, when considered from an objective point of view, does not justify the negative conclusions reached by the more severe critics of the 16PF.
Canonical analysis of a jangle fallacy
Authors: Dean R. S.
Published: May 2024

This study assessed the degree of redundancy between the WISC-R and the PIAT using a canonical correlation analysis. The test scores for 205 children yielded two significant canonical correlations. Taken together, these two Rc's indicated that over 65% of functions measured by the PIAT overlapped with the WISC-R, and 37% of the WISC-R subtest variance was shown to be redundant with the PIAT. The primary source of this nonsymmetrical redundancy was attributed to a verbal-educational overlap between measures.
Chronic welfare dependency: A multivariate analysis of personality factors
Authors: MacLean M. E.
Published: May 2024

In North America chronic welfare dependency (CWD) is a serious problem that involves millions of individuals, cost billions of tax dollars, and represents a great waste of human resources. It is postulated that CWD, over the past 30 years, has been conceptualized too simplistically and relatively unimportant variables have been emphasized in rehabilitation programs. This study suggests that, whatever the etiological factors, CWD represents a complex set of interacting personality factors. The personality factors associated with CWD suggest that rehabilitation programs need to employ multimodal and sophisticated psychotherapeutic strategies, especially those developed for the treatment of anxiety and the neuroses.
Diagnosis of the dynamic roots of a clinical symptom by P-technique: A case of episodic alcoholism
Authors: Cattell Heather Birkett , Cattell Raymond B.
Published: May 2024

A P-technique study of a middle-aged episodic alcoholic was undertaken to get at the dynamic roots of the symptom. The ten dynamic traits in the Motivation Analysis Test were measured each day for 100 occasions using 5 objective test devices summed to an unintegrated, U, and an integrated, I, component for each. They were projection, fluency, preference, word association and decision speed. A measure of appeal (dependence need) and of the strength of the symptom was similarly measured. The longitudinal correlations were highly statistically significant and were analyzed in terms of path coefficients presenting a definite analysis of the etiology of the symptom which was consistent with general clinical observations and biography.
Reliability and scope in personality assessment: A comparison of the Cattell and Eysenck inventories
Authors: Krug Samuel E.
Published: May 2024

One questionnaire designed to measure primary personality traits (the 16 PF) and another designed to measure second-order traits (the EPI) were compared in terms of reliability and comprehensiveness. Reliability differences between the two tests appeared to be due to their relative length rather than any inherent characteristics of the underlying traits. Two approaches for evaluating the overlap between the two scales were explored. The theoretical conclusion appears to be that the reliable portions of the EPI scale scores can be entirely reconstructed from a knowledge of 16 PF scores. In contrast, the EPI is far narrower in its scope and able to explain less than a third of a reliable variance in the 16 PF.
Kreuter (1842-1987), fabricant méconnu
Authors: Chabrol Marie , Coupeau Charline
Published: May 2024

The city of Hanau in Germany was one of the most important jewelry production centers of Europe between the end of the 19th century and the beginning of the 20th. It’s in this city that the Kreuter workshop was based, which ensured most of qualitative productions of many jewelers who supplied the European royal houses. Among them, Robert Koch (1879 – 1987), often described as the « German Cartier ». The general ignorance of this workshop and its archives shows that many pieces are often misidentified on the market because they are automatically attributed to its main retailer. By introducing this workshop, it is more broadly the role of the archive in the jewelry history that this article explores.
Navigating the Complex ESG Accounting Landscape: Engineering a Method Selection Framework
Authors:   Department of Information and Computing Sciences, Utrecht University, Princetonplein 5, Utrecht, 3584 CC, The Netherlands, Ramautar Vijanti , España Sergio ,   Valencian RESGArch Institute for Artificial Intelligence, Universitat Politècnica de València, Camí de Vera, 46022 València, Spain, Farshidi Siamak ,   Department of Information and Computing Sciences, Utrecht University, Princetonplein 5, Utrecht, 3584 CC, The Netherlands
Published: May 2024

Environmental, social, and governance accounting (ESGA) aids organizations in achieving their sustainability goals through continuous improvement. Suitable method selection is crucial to prevent rework, additional expenses, trivial outcomes, and reduced confidence in sustainability practices. The current ESGA method selection process lacks comprehensive consideration of alternatives and criteria, occasionally resulting in suboptimal choices. This work aims to achieve optimal ESGA by engineering a method selection framework. The research approach is based on the design cycle, where engineering decisions are informed by empirical evidence. The main findings are that the framework, which includes a decision model and a supporting information system, can reduce the chances of organizations selecting an unsuitable method, whilst sparing decision-making managers time and effort. Firstly, the reusable elements of the framework can help managers of any organization select a suitable method more efficiently since they do not have to produce these elements themselves. Secondly, the results demonstrate how selection frameworks and tools can aid organizations in navigating the complex ESG accounting landscape. Lastly, this study lowers the barrier for organizational impact management; in particular, for measuring and reporting ESG impact, which is a rigorous assessment of the organization’s progress towards sustainable development goals.
Information Security and Privacy Management in Intelligent Transportation Systems
Authors:   Institute of Computer Science, University of Tartu, Narva mnt. 18, Tartu, 51009, Estonia, Bakhtina Mariia , Matulevičius Raimundas ,   Institute of Computer Science, University of Tartu, Narva mnt. 18, Tartu, 51009, Estonia, Malina Lukaš ,   Department of Telecommunications, Faculty of Electrical Engineering and Communication, Brno University of Technology, Technicka 12, Brno, 61600, Czech Republic
Published: May 2024

With the global digitalization of services, passenger Intelligent Transportation Systems (ITSs) have emerged as transformative components, yet the practical implementation of state-of-the-art measures to ensure information security and privacy presents substantial challenges. In this article, we propose a framework for information security and privacy management. The framework is validated through two empirical studies. First, the framework is used to extract data during the literature review defining state-of-the-art aspects and measures. Second, a survey-based analysis of running passenger ITSs in selected regions of the European Union provides insights into real-life ITS implementations, enabling a thorough comparison with the proposed state-of-the-art measures. The study also showed that the proposed framework depicts some dependencies between measures, and, thus, using its matrix structure for the state of information security and privacy management in the organization helps to cross-check the usage of policies or methodologies by the organization departments. Our findings resulted in recommendations for organizations developing ITSs to enhance their information security and privacy management systems and bridge the gap between research proposals and practical implementation.
Significance of NKX2-1 as a biomarker for clinical prognosis, immune infiltration, and drug therapy in lung squamous cell carcinoma
Authors: Lin Huiyue , Wang Juyong , Shi Qing , Wu Minmin
Published: May 2024

Background

This study was performed to determine the biological processes in which NKX2-1 is involved and thus its role in the development of lung squamous cell carcinoma (LUSC) toward improving the prognosis and treatment of LUSC.

Methods

Raw RNA sequencing (RNA-seq) data of LUSC from The Cancer Genome Atlas (TCGA) were used in bioinformatics analysis to characterize NKX2-1 expression levels in tumor and normal tissues. Survival analysis of Kaplan–Meier curve, the time-dependent receiver operating characteristic (ROC) curve, and a nomogram were used to analyze the prognosis value of NKX2-1 for LUSC in terms of overall survival (OS) and progression-free survival (PFS). Then, differentially expressed genes (DEGs) were identified, and Kyoto Encyclopedia of Genes and Genomes (KEGG), Gene Ontology (GO), and Gene Set Enrichment Analysis (GSEA) were used to clarify the biological mechanisms potentially involved in the development of LUSC. Moreover, the correlation between the NKX2-1 expression level and tumor mutation burden (TMB), tumor microenvironment (TME), and immune cell infiltration revealed that NKX2-1 participates in the development of LUSC. Finally, we studied the effects of NKX2-1 on drug therapy. To validate the protein and gene expression levels of NKX2-1 in LUSC, we employed immunohistochemistry(IHC) datasets, The Gene Expression Omnibus (GEO) database, and qRT-PCR analysis.

Results

NKX2-1 expression levels were significantly lower in LUSC than in normal lung tissue. It significantly differed in gender, stage and N classification. The survival analysis revealed that high expression of NKX2-1 had shorter OS and PFS in LUSC. The multivariate Cox regression hazard model showed the NKX2-1 expression as an independent prognostic factor. Then, the nomogram predicted LUSC prognosis. There are 51 upregulated DEGs and 49 downregulated DEGs in the NKX2-1 high-level groups. GO, KEGG and GSEA analysis revealed that DEGs were enriched in cell cycle and DNA replication.The TME results show that NKX2-1 expression was positively associated with mast cells resting, neutrophils, monocytes, T cells CD4 memory resting, and M2 macrophages but negatively associated with M1 macrophages. The TMB correlated negatively with NKX2-1 expression. The pharmacotherapy had great sensitivity in the NKX2-1 low-level group, the immunotherapy is no significant difference in the NKX2-1 low-level and high-level groups. The analysis of GEO data demonstrated concurrence with TCGA results. IHC revealed NKX2-1 protein expression in tumor tissues of both LUAD and LUSC. Meanwhile qRT-PCR analysis indicated a significantly lower NKX2-1 expression level in LUSC compared to LUAD. These qRT-PCR findings were consistent with co-expression analysis of NKX2-1.

Conclusion

We conclude that NKX2-1 is a potential biomarker for prognosis and treatment LUSC. A new insights of NKX2-1 in LUSC is still needed further research.
Port Site Hernia after Laparoscopic Surgery: Incidence, Pathogenesis and Management Strategies
Authors: Kshirsagar Vinayak Vishnupant , Langade Yogesh Bhupal , Nichkaode Prabhat Bhaskarrao , Memane Nilam Sandeep , Kothavale Rakesh Diliprao
Published: May 2024

Although Port Site Hernia (PSH) is a rare complication after laparoscopic surgery, with an incidence of 0.65-2.8%, it can be deadly due to the inherent risk of bowel strangulation. Various factors like trocar size, design, improper closure of the defect, and postoperative infection may cause PSH, and symptoms might occur immediately within 10 days or up to 18 months of the primary procedure. A Computed Tomography (CT) scan is a helpful adjuvant in the diagnosis and evaluation of PSH. Deformities larger than 5 mm require surgical intervention in all age groups. Early cases of suspected gangrene necessitate immediate surgical intervention. In advanced situations, anatomical repair by suture or mesh repair by open or laparoscopic method is preferred for lesions larger than 5 mm.
Health Risk Assessment of Organochlorine Pesticide Residues in Selected Herbal Medicines Sold in Lagos State, Nigeria
Authors: Ajoke Oye Ranti
Published: May 2024

The use of herbal medicines has a very long history for therapeutic purposes. However, cases of toxicological effects have been reported. The present study aims to assess the safety level of herbal medicines by monitoring the organochlorine pesticide (OCP) residues content. This study assessed the presence of seventeen organochlorine pesticide residues in twenty-seven (27) herbal medicine samples (14 liquid and 13 solid) collected from seven Local Government Area of Lagos state, Nigeria. The residues were analyzed using Gas Chromatography-Mass Spectrometry (GC-MS) with solid phase extraction. Results showed the presence of banned OCP residues in all the selected samples at concentrations greater than the Maximum Residue limit, MRL. The Estimated Daily Intake, EDI measures the level of exposure to the pesticide residues for all the samples were found to be lower than the Acceptable Daily Intake, ADI. Health Risk Index (HRI) of all the selected samples was generally lesser than one (1) which indicates that long term exposure may not be of immediate concern to the consumers. The solid herbal medicines were found to have higher mean concentration, EDI and HRI when compared to the liquid herbal samples, suggesting that processing and preparation techniques for solid herbal medicines should be improved. The presence of the banned OCP residues in herbal medicine is, however, of public health interest and should be regularly monitored.
The Effect of Environmental Regulation on the Competitiveness of Pharmaceutical Manufacturing Industry
Authors: Wang Yuqin , Sun Jun
Published: May 2024

Environmental regulation, as a tool for the government and society to reduce environmental pollution and achieve social civilization and sustainable economic development, has long been a key factor in economic development, and it is of great significance to explore the impact of environmental regulation on the competitiveness of the pharmaceutical manufacturing industry on the development of China's manufacturing industry. Based on China's provincial panel data from 2011-2021, an evaluation system is constructed from four dimensions: scale, efficiency, innovation and input, the entropy method is applied to measure the competitiveness indicators of China's pharmaceutical manufacturing industry, and a benchmark regression is constructed through a two-way fixed-effects model, and heterogeneity test, robustness test and mediation test are conducted. It is found that environmental regulation has a significant positive effect on the competitiveness of China's pharmaceutical manufacturing industry, and there are differences in the impact on each region. In addition to direct empowerment, environmental regulation also enhances the competitiveness of pharmaceutical manufacturing industry through technological innovation, and its mediation effect is significant. Finally, based on the above findings, it is recommended that the intensity of environmental regulations and subsidies should be increased, differentiated environmental regulation policies should be formulated, and milder market interventions should be used to create a healthy and positive market environment, and the introduction of scientific and technological talents should be increased in order to enhance the scientific research strength of China's pharmaceutical manufacturing industry.
Macrophagic Activation Syndrome Revealing Tuberculosis: A Case Report
Authors: Majd R. , Radi A. , Laarej A. , Hassani A. , Abilkassem R.
Published: May 2024

We present a case involving an immunocompetent infant diagnosed with miliary tuberculosis complicated by macrophage activation syndrome. Macrophage activation syndrome (MAS), also known as bone marrow hemophagocytosis, presents as a non-specific clinical condition characterized by fever and hepatosplenomegaly. A 22-month-old infant from a non- consanguineous marriage, the only child in the family, was admitted to a regional hospital due to prolonged fever lasting 15 days. The syndrome can manifest as a primary disorder (familial HLH) due to various genetic mutations or as a sporadic secondary disorder triggered by infections, autoimmune diseases, or malignant conditions. The early initiation of antibacillary treatment in AMS complicating tuberculosis without the use of immunosuppressive drugs provides better management and improves the vital prognosis.
A Season-wise Analysis of the Extent of Adoption of Popular Rice Varieties in Telangana, India
Authors: Satish S. , Bandumula Nirmala , Pathak Hulas
Published: May 2024

Rice is a vital staple food worldwide, serving as a major source of calories for a significant portion of the global population. In India, where agriculture plays a pivotal role in the economy, rice production has witnessed remarkable growth over the past few decades. This growth is supported by advancements in agricultural technology, including the introduction of high-yielding seeds, chemical fertilizers, and agrochemicals. India stands as a key player in rice production, covering vast areas and contributing significantly to the nation's food grain output.
Telangana, a state in India, has seen a substantial increase in paddy production, owing to government initiatives, irrigation projects, and investments. The development of high-yielding rice varieties that are well-suited to the region's soil conditions has played a crucial role in this growth. These varieties exhibit resistance to various biotic and abiotic stresses, contributing to a sustained increase in paddy production. The state's remarkable progress in rice cultivation is evident through the data on area coverage, production, and productivity The study delves into the area coverage of popular rice varieties across seasons in Telangana. It reveals that coarse and fine rice varieties dominate Kharif and Rabi seasons, respectively, with MTU 1010 being the most extensively cultivated. This article provides valuable insights into the extent of adoption of popular rice varieties among farmers of Telangana.
Evaluation of Some Green Gram Genotypes against Whitefly, Bemisia tabaci Gennadius and Leafhopper, Empoasca kerri Pruthi under Field Conditions
Authors: Narasimhudu Manipati , Dahiya Bilochan , Singh S. P. , Sharma S. S.
Published: May 2024

Studies were carried out on 51 genotypes of green gram, evaluated to identify the genotypic response against whitefly, leafhoppers and yellow mosaic virus infestation during kharif, 2010 at CCS Haryana Agricultural University, Hisar. Out of 51 genotypes, MH 732, MH 717, MH 719 and MH - 125 (Basanti) and MH 717 harboured minimum population of whitefly (2.68 /cage/plant), green leafhopper (0.45 /cage/plant), brown leafhopper (0.15 /cage/plant) and mixed (green and brown) leafhopper (0.69 /cage/plant), respectively, as compared to maximum whitefly population observed on genotype SM 9-117 (8.30 /cage/plant), green leafhopper on MH 809 (1.12 /cage/plant), brown leafhopper on MH 748 and MH 808 (0.41 /cage/plant) and mixed leafhopper counts recorded on SM 9-113 (1.49 /cage/plant). Genotype MH 742 affected least 2.80 per cent with the incidence of YMV as compared to maximum (56 per cent) incidence on SM 9-112. Highest grain yield (908 kg/ha) was obtained from the genotype MH 742 as compared to 355 kg/ha lowest observed from the genotype SM 9-112.
Effect of Ethanolic Leaf Extract of Piper guineense (Uziza) on the Kidneys of Paraquat-Induced Adult Male Wistar Rats
Authors: Adolphus Mbah Chikodili , Lilian Okwuanga, Nkiruka , Omo Irinmwinuwa Eric , Bernard Oyate Godwin , Kenechukwu Nwanama Emmanuel , Eberechukwu Ezejimofor Perpetua
Published: May 2024

Background: Paraquat (PQ) is one of the most toxic environmental pollutants.
Objectives: This study was conducted to determine the effect of an ethanolic leaf extract of piper guineense on the kidneys of paraquat-induced adult Wistar rats.
Methods: In this study, rats were divided into six groups. The control group (group A) received distilled water, and 20mg/kg of Paraquat was induced in groups B, C, D, E, and F; group C received 200mg/kg, group E received 80mg/kg, and group F received 100mg/kg of ethanolic leaf extract of Piper guineense, respectively. The animals were treated for 28 consecutive days. After the urea and serum creatinine collection, kidney histopathology was investigated.
Results: PQ increased relative organ weight, urea, and serum creatinine levels, but it significantly decreased body weight across groups B and D. In the groups treated with piper guineense, urea and creatinine decreased compared with the PQ group, and body weight levels increased. Severe intra-renal inflammation and haemorrhage, necrotic debris around the hemorrhagic area, was seen histopathologically. The effects were ameliorated in Groups E and F, which received variable doses of the ethanolic leaf extracts of P. guineense.
Conclusion: The obtained findings revealed that P. guineense leaf extract, used as a preventive compound, was able to reduce kidney dysfunction and tissue damage caused by PQ toxicity in the kidney.
Diversity of Fungi and Bacteria Associated with Respiratory Infections among Commercial Bank Tellers in South-Eastern Nigeria
Authors: Chigbu Lawrence Nwaneri , Kelechi Chigbu Nwaneri, , Ikonne Chikezie , Kendra Jumbo Ugonma , Nwokocha Onwuchekwa, Uwa
Published: May 2024

Introduction: Fungi - associated respiratory Infections are serious health challenges that have become inextricably linked with handling of paper currencies in some countries of the world Dermici et al., [1]. Given the quantity of Old-worn-out and mutilated Naira notes in circulation, and other prevailing circumstances in Nigerian banking halls, study was undertaken to evaluate the incidence and spread of fungi -associated respiratory infections among tellers from selected commercial Banks in South-Eastern Nigeria.
Methods: A total of 504 Cash Bank Tellers; 196 Males and 308 females aged 25 – 48years (mean age 32.4 years) were evaluated for Fungi-associated infections using Sputum and Nasal secretions-smear Microscopy and Culture simultaneously. Twenty-Seven bacterial strains; Staphylococcus aureus (12), Streptococcus Pneumonia (7) and Klebsiella pneumoniae (8) were tested for their antibiogram
Results: One hundred and fifty-nine (31.5%) of the 504 Bank Cash Tellers were diagnosed of respiratory infections due to Aspergillus Sp. (13.5%), Candida albicans (5.8%), Candida tropicalis 6(.4%), Staphylococcus aureus (2.4%), Streptococcus pneumoniae (1.4%), Klebsiella pneumoniae (1.6%), and Nocardia Sp. (0.6%). The yield of micro-pathogens appeared to rise from 18.8% to 55.6% as duration of currency note handling increased from ≤ 6months to 43 – 48 months respectively. Analysis of the differences of the Micro-Pathogens isolated among tellers from Bulk Rooms (42.9%) and those from open Halls (20.2%) was statistically significant (X2cal=68.3) P < 0.05. Forty-eight (88.9%), 26(123.8%), 41(44.6%) and 43(113.2%) Strains of micro-pathogens were isolated from Tellers who indicated with history of respiratory infections, smoking only, alcohol consumption only and smoking/alcohol consumption respectively. The proportions of the micro-pathogens isolated are shown in the Table 1, with Aspergillus sp. yield appearing highest. The antibiogram of the 27 strains of bacteria isolated in the study appeared relatively high; 92.6% for Ofloxacin and 66.7% for Gentamycin, while Streptomycin, Erythromycin, Cephalexin, Ampiclox, and Chloramphenicol responded poorly.
Conclusion: The micro-pathogens isolated from this study are important agents of respiratory infections. The relatively high proportions (31.6%) of micro-pathogens isolated may serve as relevant indication that most Nigerian Currency notes in circulation are old, worn-out, mutilated, and are contaminated with micro-pathogens commonly linked with serious public health problems.
Generational differences in cultural life scripts and life story memories of younger and older adults
Authors: Bohn Annette
Published: November 2009

Groups of younger and older participants produced cultural life scripts by listing the seven most important life events and the expected timing of these events for a hypothetical person. They also produced the seven most important life story memories from their own lives. Cultural life scripts and life story memories were rated on valence. Scales on depression, satisfaction with life, and the centrality of an event for identity and the life story were administered. A stable cultural life script was found across the two generations, with a clear bump for positive events in adolescence and early adulthood. However, older adults produced a more realistic, less idealized life script than younger adults. The overlap between life script events and life story memories increased with age. Having a negative event central to one's life story and identity was related to less life satisfaction and, in the young group, higher depression scores. Copyright © 2009 John Wiley & Sons, Ltd.
Microstructure Tailored Functionally Graded Alumina/Lanthanum Hexaaluminate Ceramics for Application as Thermal Barrier Coatings
Authors: Negahdari Zahra , Willert‐Porada Monika
Published: November 2009

The thermal and mechanical properties of a functionally graded lanthanum hexaaluminate‐alumina ceramic are described. The gradation of functionality is based on different volume fraction of lanthanum hexaaluminate, varying from 0 to 80 vol% and corresponding porosity from 2 to 32 vol%. The highest volume fraction of lanthanum hexaaluminate enables a five time reduced thermal diffusivity as compared to alumina. The fracture toughness and elastic modulus is highest for a 20 vol% lanthanum hexaaluminate‐alumina composite.
Electronic Structure of Self‐Assembled Monolayers on Au(111) Surfaces: The Impact of Backbone Polarizability
Authors: Wang LinJun , Rangger Gerold M. , Romaner Lorenz , Heimel Georg , Bučko Tomas , Ma ZhongYun , Li QiKai , Shuai Zhigang , Zojer Egbert
Published: November 2009

Modifying metal electrodes with self‐assembled monolayers (SAMs) has promising applications in organic and molecular electronics. The two key electronic parameters are the modification of the electrode work function because of SAM adsorption and the alignment of the SAM conducting states relative to the metal Fermi level. Through a comprehensive density‐functional‐theory study on a series of organic thiols self‐assembled on Au(111), relationships between the electronic structure of the individual molecules (especially the backbone polarizability and its response to donor/acceptor substitutions) and the properties of the corresponding SAMs are described. The molecular backbone is found to significantly impacts the level alignment; for molecules with small ionization potentials, even Fermi‐level pinning is observed. Nevertheless, independent of the backbone, polar head‐group substitutions have no effect on the level alignment. For the work‐function modification, the larger molecular dipole moments achieved when attaching donor/acceptor substituents to more polarizable backbones are largely compensated by increased depolarization in the SAMs. The main impact of the backbone on the work‐function modification thus arises from its influence on the molecular orientation on the surface. This study provides a solid theoretical basis for the fundamental understanding of SAMs and significantly advances the understanding of structure–property relationships needed for the future development of functional organic interfaces.
Indentation as a technique to assess the mechanical properties of fallback foods
Authors: Lucas Peter W. , Constantino Paul J. , Chalk Janine , Ziscovici Charles , Wright Barth W. , Fragaszy Dorothy M. , Hill David A. , Lee James J.‐W. , Chai Herzl , Darvell Brian W. , Lee Paul K.D. , Yuen Tony D.B.
Published: November 2009

A number of living primates feed part‐year on seemingly hard food objects as a fallback. We ask here how hardness can be quantified and how this can help understand primate feeding ecology. We report a simple indentation methodology for quantifying hardness, elastic modulus, and toughness in the sense that materials scientists would define them. Suggested categories of fallback foods—nuts, seeds, and root vegetables—were tested, with accuracy checked on standard materials with known properties by the same means. Results were generally consistent, but the moduli of root vegetables were overestimated here. All these properties are important components of what fieldworkers mean by hardness and help understand how food properties influence primate behavior. Hardness sensu stricto determines whether foods leave permanent marks on tooth tissues when they are bitten on. The force at which a food plastically deforms can be estimated from hardness and modulus. When fallback foods are bilayered, consisting of a nutritious core protected by a hard outer coat, it is possible to predict their failure force from the toughness and modulus of the outer coat, and the modulus of the enclosed core. These forces can be high and bite forces may be maximized in fallback food consumption. Expanding the context, the same equation for the failure force for a bilayered solid can be applied to teeth. This analysis predicts that blunt cusps and thick enamel will indeed help to sustain the integrity of teeth against contacts with these foods up to high loads. Am J Phys Anthropol 140:643–652, 2009. © 2009 Wiley‐Liss, Inc.