bluuebunny/crossref_metadata_2025 huggingface dataset:
Visual impairment and psychological distress among adults attending the University of Gondar tertiary eye care and training center, Northwest Ethiopia: A comparative cross-sectional study
Authors: Munaw Minychil Bantihun , Tegegn Melkamu Temeselew
Published: February 2022

Background

Visual impairment can severely affect the quality of life, with a tremendous negative impact on job performance and socioeconomic status. This substantially affects the psychological status of people with visual impairment.

Objective

This study aimed to determine the prevalence and factors associated with psychological distress among visually impaired Ethiopian adults attending the University of Gondar Tertiary Eye Care and Training Center.

Methods

A comparative cross-sectional study was conducted at the University of Gondar Tertiary Eye Care and Training Center in Gondar City, northwest Ethiopia. A total of 206 adults with visual impairment (a presenting VA ≤ 6/18 in at least one eye) and 206 adults with normal vision were included in the study. Psychological distress was measured using a standardized self-reporting questionnaire (SRQ-20). Chi-square and binary logistic regression analysis were performed. Variables with a P-value of less than 0.05 were considered statistically significant.

Results

The overall prevalence of psychological distress in the study participants was 31.07% (95% CI: 26.2, 35.8). Psychological distress was higher (43.2%; 95% CI: 36.5, 50.5) and statistically differed (p = 0.02) in visually impaired compared to adults with normal vision (18.9%; 95% CI: 14.1, 24.3). Duration of vision loss ≥ 2 years (AOR = 8.70; 95% CI: 2.38, 31.46), sudden loss of vision (AOR = 3.50; 95% CI: 1.10, 18.30), unmarried (AOR = 5.53; 95% CI: 1.66, 18.43), living lonely (AOR = 8.40; 95% CI:1.48, 4.74), College and above educational status (AOR = 2.50; 95% CI:1.47, 10.61), and loss of vision in both eyes (AOR = 1.70; 95% CI: 2.00, 14.10) were variables with a significant association with psychological distress among visually impaired adults.

Conclusion

This study revealed that the prevalence of psychological distress was significantly higher among visually impaired adults than among adults with normal vision. The effect of visual impairment on psychological distress was significantly related to marital status, living arrangements, educational status, duration of vision loss, pattern of vision loss, and laterality of vision loss.
Machine learning-based prediction of critical illness in children visiting the emergency department
Authors: Hwang Soyun , Lee Bongjin
Published: February 2022

Objectives

Triage is an essential emergency department (ED) process designed to provide timely management depending on acuity and severity; however, the process may be inconsistent with clinical and hospitalization outcomes. Therefore, studies have attempted to augment this process with machine learning models, showing advantages in predicting critical conditions and hospitalization outcomes. The aim of this study was to utilize nationwide registry data to develop a machine learning-based classification model to predict the clinical course of pediatric ED visits.

Methods

This cross-sectional observational study used data from the National Emergency Department Information System on emergency visits of children under 15 years of age from January 1, 2016, to December 31, 2017. The primary and secondary outcomes were to identify critically ill children and predict hospitalization from triage data, respectively. We developed and tested a random forest model with the under sampled dataset and validated the model using the entire dataset. We compared the model’s performance with that of the conventional triage system.

Results

A total of 2,621,710 children were eligible for the analysis and included 12,951 (0.5%) critical outcomes and 303,808 (11.6%) hospitalizations. After validation, the area under the receiver operating characteristic curve was 0.991 (95% confidence interval [CI] 0.991–0.992) for critical outcomes and 0.943 (95% CI 0.943–0.944) for hospitalization, which were higher than those of the conventional triage system.

Conclusions

The machine learning-based model using structured triage data from a nationwide database can effectively predict critical illness and hospitalizations among children visiting the ED.
Glucosyltransferase-dependent and independent effects of Clostridioides difficile toxins during infection
Authors: Peritore-Galve F. Christopher , Shupe John A. , Cave Rory J. , Childress Kevin O. , Washington M. Kay , Kuehne Sarah A. , Lacy D. Borden
Published: February 2022

Clostridioides difficile infection (CDI) is the leading cause of nosocomial diarrhea and pseudomembranous colitis in the USA. In addition to these symptoms, patients with CDI can develop severe inflammation and tissue damage, resulting in life-threatening toxic megacolon. CDI is mediated by two large homologous protein toxins, TcdA and TcdB, that bind and hijack receptors to enter host cells where they use glucosyltransferase (GT) enzymes to inactivate Rho family GTPases. GT-dependent intoxication elicits cytopathic changes, cytokine production, and apoptosis. At higher concentrations TcdB induces GT-independent necrosis in cells and tissue by stimulating production of reactive oxygen species via recruitment of the NADPH oxidase complex. Although GT-independent necrosis has been observed in vitro, the relevance of this mechanism during CDI has remained an outstanding question in the field. In this study we generated novel C. difficile toxin mutants in the hypervirulent BI/NAP1/PCR-ribotype 027 R20291 strain to test the hypothesis that GT-independent epithelial damage occurs during CDI. Using the mouse model of CDI, we observed that epithelial damage occurs through a GT-independent process that does not involve immune cell influx. The GT-activity of either toxin was sufficient to cause severe edema and inflammation, yet GT activity of both toxins was necessary to produce severe watery diarrhea. These results demonstrate that both TcdA and TcdB contribute to disease pathogenesis when present. Further, while inactivating GT activity of C. difficile toxins may suppress diarrhea and deleterious GT-dependent immune responses, the potential of severe GT-independent epithelial damage merits consideration when developing toxin-based therapeutics against CDI.
Evaluation of the in vitro and in vivo antioxidant potential of Punica granatum L. against toluene-induced liver injuries in rats
Authors: Arkoub Fatma Zohra , Hamdi Leila , Kahalerras Labiba , Hamoudi Meriem , Khelili Kamel
Published: February 2022

Background and Aim: Humans are more frequently exposed to chemicals in daily life by inhalation of indoor and outdoor air. However, abusers and workers are the most exposed to those chemicals and their health risks particularly, liver diseases. The present study investigated the protective effects of pomegranate juice (PJ) (Punica granatum) and pomegranate peel aqueous extract (PAE) supplementation against toluene (Tol)-induced hepatotoxicity in Wistar rats.

Materials and Methods: A phytochemical analysis and assessment of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity were performed for the PJ and the PAE. The in vivo study was carried out using 70 Wistar rats that were divided into seven groups, each consisting of 10 rats. All groups were treated orally for 6 weeks as follows: Control (C), positive controls (CO: 1.25 mL/kg body weight [BW]; PJ: 4 mL/kg BW; and PAE: 400 mg/kg BW), Tol (550 mg/kg BW), and a mixture each of PJ-Tol and PAE-Tol. At the end of the 45th day of study, the hepatic biochemical markers (transaminases, alkaline phosphatase, total bilirubin, albumin, and total proteins) were auto-analyzed, as well as histology and oxidative stress markers of the liver were evaluated.

Results: The phytochemical analysis revealed that the DPPH scavenging activity and the total phenolic, flavonoid, and tannin contents were higher in the pomegranate peel extract versus the juice. The results also showed that Tol significantly increased liver enzyme activities and total bilirubin levels, whereas albumin and total proteins were significantly decreased. Similarly, Tol provoked a significant increase in hepatic malondialdehyde levels, with a decrease in glutathione content and glutathione peroxidase activity. The biochemical changes agreed with the hepatic histological alterations. A significant improvement in all parameters was observed in the PAE-Tol group compared with the PJ-Tol group.

Conclusion: Exposure to Tol altered the hepatic antioxidant and biochemical parameters and histological profile of the rats, and PAE was more powerful than PJ in reducing Tol liver injuries through its antioxidant activity.
Performance assessment and strengthening proposal of an existing building
Authors: Lakusic Stjepan
Published: February 2022

Due to major-scale earthquakes, revisions of earthquake resistant structural design methods have periodically been made in seismic codes. It is known that many existing buildings are located in active seismic zones in all parts of the world. Severe damage to structural members, with partial or total collapse of buildings, has been observed in past earthquakes. Consequently, the evaluation of seismic performance and strengthening techniques of the existing buildings according to various seismic codes has become a global issue in structural engineering. With the development of computer technology, non-linear methods have been offering increasingly reliable evaluation procedures in the performance-based assessment of buildings. In this study, non-linear performance analysis of an existing typical mid-rise reinforced concrete building is first performed according to Turkish Building Earthquake Code-2018 and American Standard, ASCE. After evaluation of damage to structural members, the building is strengthened by steel braces and the analysis is performed once again. The SAP2000 finite elements analysis software is utilized in the solutions. Damage ratios of structural members as well as modal properties and storey drift ratios are determined and compared according to both codes, and it is concluded that the proposed strengthening method could be a significant alternative in such buildings.
Preocupación por el contagio de la COVID-19, apoyo social en el trabajo y ansiedad como predictores de la depresión en enfermeras peruanas
Authors: Carranza Esteban Renzo Felipe , Mamani-Benito Oscar , Quinteros-Zúñiga Dámaris , Caycho-Rodríguez Tomás , Blanco Shocosh Darwin
Published: February 2022

Objetivo: Determinar si la preocupación por la COVID-19, el apoyo social y la ansiedad son predictores de la depresión en enfermeras peruanas durante la emergencia sanitaria. Material y Métodos: Estudio predictivo de corte transversal, realizado en 216 enfermeras peruanas, a quienes se aplicó la Escala de Apoyo Social en el Trabajo (EAST), la Escala de Preocupación por la COVID-19 (EPPC-Cov19), la Generalized Anxiety Disorder Scale-2 (GAD-2) y el Patient Health Questionnarie-2 (PHQ-2). Los datos se analizaron mediante coeficientes de correlación y modelos de regresión lineal múltiple. Resultados: Se reportaron correlaciones significativas entre la preocupación por la COVID-19, ansiedad y depresión. Los análisis de regresión muestran un ajuste adecuado del modelo (Prueba F = 76,064, p < .001), donde la preocupación por el contagio de la COVID-19 (? = ,316, p < .01) y la ansiedad (? = ,417, p < .01), son variables que predicen significativamente la depresión en enfermeras peruanas (R2 ajustado = .39). Asimismo, los valores t de los coeficientes de regresión beta de las variables predictoras son altamente significativas (p < 0.01). Conclusión: Se concluye que experimentar preocupación por el contagio de la COVID-19 y la ansiedad predicen la aparición de síntomas depresivos en enfermeras peruanas que se encontraron trabajando en el contexto de la emergencia sanitaria.
Eficacia de las estrategias en rehabilitación para la salud mental de pacientes en adicción a drogas. Revisión sistemática
Authors: Meneses Castaño Cyndi Yacira
Published: February 2022

La adicción a drogas es un trastorno mental que puede llegar a ser de tipo crónico y reiterativo, caracterizándose por un componente principal llamado la impulsividad. El objetivo de esta investigación fue evaluar la eficacia de las estrategias en rehabilitación para la salud mental de pacientes en adicción a drogas; para ello se llevó a cabo una revisión sistemática de ensayos controlados aleatorizados. Se incluyeron estudios de los últimos cinco años que compararon las estrategias en rehabilitación para la salud mental con otro tipo de intervención o ninguna. Para la evaluación de la calidad metodológica de los estudios incluidos se utilizó la escala PEDro, así como la evaluación del nivel de evidencia y grado de recomendación de acuerdo con la clasificación dada por Oxford. De 251 registros encontrados, catorce artículos cumplieron con los criterios de elegibilidad y fueron incluidos para el análisis cualitativo. Las intervenciones relacionadas con la rehabilitación de pacientes para la salud mental en adicción a drogas son heterogéneas y enfatizan en mayor medida en entrenamiento de funciones cognitivas, ejercicio físico, componentes motivacionales, conductuales y de regulación emocional.
Estrés, ansiedad, depresión y apoyo familiar en universitarios mexicanos durante la pandemia de COVID-19
Authors: Peréz-Pérez Mariana , Fernández-Sánchez Higinio , Enríquez-Hernández Claudia  Beatriz , López-Orozco Graciela , Ortiz-Vargas Israel , Gómez-Calles Tomás Jesús
Published: February 2022

Objetivo: Identificar los niveles de estrés, ansiedad y depresión presentes en los universitarios durante la pandemia en relación con el apoyo que brinda la familia. Materiales y Métodos: Se trata de un estudio de tipo cuantitativo con un diseño descriptivo, correlacional y transversal. La muestra (n=105), fueron estudiantes de la facultad de Enfermería de la Universidad Veracruzana; se obtuvo a través de un muestreo no-probabilístico a conveniencia. Los datos fueron recolectados a través de un instrumento digital (Google Forms). Las variables se midieron utilizando la Escala de Depresión, Ansiedad y Estrés (DASS-21) y el Inventario de Percepción de Apoyo Familiar (IPAF). Los datos fueron analizados mediante estadística descriptiva y la prueba de correlación de Spearman.Resultados: Los resultados evidencian que no existe una asociación entre las variables estudiadas r=-0.192, n=105, p=0.134., pero si existe depresión (85.8%), ansiedad (84%) y estrés (77.4%) en los estudiantes, aunque se presenta de forma leve y un nivel medio bajo de apoyo familiar (afecto 61.3%, adaptabilidad 62.3% y autonomía 40.6%).Conclusión: Los trastornos por ansiedad, estrés y depresión afectan gradualmente diversas esferas de actuación personal de los estudiantes, por lo cual una intervención oportuna y preventiva es relevante.
Academy of Geriatric Physical Therapy Research Agenda: Rationale for the Development and the Intent for Use
Authors: VanSwearingen Jessie , Knox Sara , Lowry Kristin A. , Allison Leslie K. , Ciolek Cathy , Miller Kenneth L. , Avin Keith G. , Hartley Greg W.
Published: February 2022

The rationale for the development and the intent for use of a research agenda for the Academy of Geriatric Physical Therapy is described. The reasons for the research agenda for geriatric physical therapy are (1) to have a broad representation of the research conducted by physical therapist(s) working with older adults, (2) to provide guidance and assistance to emerging investigators to aid the trajectory of a research career, and (3) as a document to engage potential funding agencies, foundations, and individuals in support of physical therapist-conducted research. The design was based on the Research Agenda for Physical Therapy (APTA document), formatted to be consistent with the World Health Organization International Classification of Functioning, Disability and Health, priority ratings for the research statements, and specific examples of research questions for each category of the Research Agenda. The Academy of Geriatric Physical Therapy Research Agenda generated to be a living document, with revisions to research questions and priority ratings expected in the future to enable the agenda to adapt to changes in science, practice, workforce, education, and health policy.
„Mordujmy się!”. Dekonstrukcja polskiej tożsamości narodowej w Lilli Wenedzie Juliusza Słowackiego i teatralnej recepcji dramatu
Authors:   Wydział Filologiczny, Uniwersytet w Białymstoku, Zimnoch Karol
Published: February 2022

The article analyses the concept of Polish national identity in Juliusz Słowacki’s Lilla Weneda. The author argues that Słowacki shows in the drama the genesis of Poles as a nation which came into being as a result of the bloody conquest of the Venedians by the Lechits. By doing that, the poet uses irony to deconstruct Polish identity based on a sense of injustice and marked by unprocessed trauma. In his considerations, he takes into account the theatrical reception of the tragedy, which proves its ambivalent character.
The interplay of thyroid hormones and the immune system – where we stand and why we need to know about it
Authors: Wenzek Christina , Boelen Anita , Westendorf Astrid M , Engel Daniel R , Moeller Lars C , Führer Dagmar
Published: February 2022

Over the past few years, growing evidence suggests direct crosstalk between thyroid hormones (THs) and the immune system. Components of the immune system were proposed to interfere with the central regulation of systemic TH levels. Conversely, THs regulate innate and adaptive immune responses as immune cells are direct target cells of THs. Accordingly, they express different components of local TH action, such as TH transporters or receptors, but our picture of the interplay between THs and the immune system is still incomplete. This review provides a critical overview of current knowledge regarding the interaction of THs and the immune system with the main focus on local TH action within major innate and adaptive immune cell subsets. Thereby, this review aims to highlight open issues which might help to infer the clinical relevance of THs in host defence in the context of different types of diseases such as infection, ischemic organ injury or cancer.
Application of a Heterodyne Laser System to Determine Parameters of Turbulent Atmosphere
Authors: Vildanov R. , Eshonqulov G.
Published: February 2022

The use of a heterodyne laser system in atmospheric measurements has been proposed. The continuous registration of optical phase variations of radiation propagating in the atmospheric channel has been carried out. From recorded data, the integral characteristics of a turbulence state in the radiation propagation channel are obtained.
Енергетичний аналіз комплексоутворення ароматичних молекул у водному розчині
Authors: Костюков В.В. , Твердохліб Н.М. , Євстигнєєв М.П.
Published: February 2022

Представлено аналіз енергетики нековалентних взаємодій при самоасоціації 12 ароматичних молекул, різних за структурою та зарядом. Розроблено методику обчислення внесків різних фізичних чинників у повну енергію Гіббса. Виявлено, що внески водневих зв'язків та ентропійні чинники завжди сприятливі, тоді як ван-дер-ваальсівські, електростатичні та (або) гідрофобні взаємодії можуть бути стабілізуючими чи дестабілізуючими чинниками залежно від досліджуваної системи. Аналіз, який проведено у даній роботі, дає відповідь на питання: які чинники стабілізують/дестабілізують стекінг ароматичних молекул у розчині та яка їх відносна важливість.
Електронна функція Гріна графена в потенціалі Ааронова−Бома
Authors: Слободенюк А.О.
Published: February 2022

Розглянуто динаміку електронних збуджень (які описуються рівнянням Дірака) у графені в полі Ааронова–Бома. Власні функції і спектр гамільтоніана системи використовуються для побудови електронної функції Гріна. Показано, що вона може бути представлена в інтегральній формі. Обговорено можливе застосування отриманих результатів для чисельних розрахунків електронних властивостей графена.
Migration & Religion
Authors: Mattes Astrid
Published: February 2022

How are migration and religion related? In the Austrian context, this question is mostly reduced to debates on whether Islam belongs to Austria and whether Muslims are integrated into society. The book “Migration and Religion” asks more fundamental questions. How are migration movements and changing religious landscapes connected? Which societal and institutional adaption processes are provoked by migration regarding the handling of religion? Why is religion such a dominant subject in migration discourses? Which party-political considerations concern the intersection of religion and migration? How is religion related to debates about shared values? And what are the roles of international actors when it comes to religion and migration? The author presents state-of-the-art results from the fields of research migration and religious studies in an easily understandable format. In each chapter the author discusses the issues at hand from different theoretical perspectives, to allow for a variety of angles. Readers are introduced to the perspectives of liberal theory, social constructivism, and multiculturalism, practically discussed through examples from Austria, such as the reform of the Islam Law, Christian Orthodoxy as a migrant religious community below the radar, and the ban of headscarves in schools. The book concludes by sketching future prospects for society, research, religious communities, and politics at the intersection of religion and migration.
Sheikh Burhanuddin's Cultural Da'wah System in Minangkabau
Authors: Nazirman Nazirman , Saharman Saharman , Sihombing Abdul Manan
Published: February 2022

This discourse describes Syekh Burhanuddin's cultural da'wah system in Minangkabau as one of the classical da'wah role models that have taken root and preserved to this day. This study aims to reveal the structure and system of da'wah built by Syekh Burhanuddin through a qualitative research method with a historical, descriptive analysis approach. The data collection technique used snowball sampling by taking locations in Ulakan Padang Pariaman, Kenagarian Puluik-Puluik and Kapujan Bayang Pesisir Selatan, Kenagarian Agarng Payung Sekaki, Solok district, and Koto Tangah, Padang City. The research shows that Sheikh Burhanuddin's cultural da'wah system is integrated and has a multi-level da'wah pattern in the da'wah network known as the seven pillars of syattariyyah da'wah, including: Syekh Tuo Koto Tuo, Tuanku Qadi in Lubuk Ipuh, Angku Qadi seven Koto (Toboh Karambia), Tuanku Qadhi Koto Gadang, Ampu Sarak in Sintuak, Tuanku Qadi Toboh Gadang, and Tuanku Qadi in Pakandangan. The seven pillars are representative reflections of the modeling of cultural da'wah in Minangkabau.
PENERAPAN GOOD MANUFACTURING PRACTICE (GMP) DAN SANITASION STANDARD OPERATION PROCEDURES (SSOP) PADA PENGOLAHAN UDANG VANNAMEI (Litopenaeus vannamei) KUPAS MENTAH BEKU Peeled Deveined (PD)
Authors: Hafina Abrar , Sipahutar Yuliati H , Siregar Arpan N
Published: February 2022

Udang vanamei (Litopenaeus vannamei) merupakan salah satu produk perikanan yang mempunyai nilai ekonomis penting. Produk ini memiliki faktor penentu sebagai komoditas ekspor dalam perdagangan internasional. Untuk itu, diperlukan proses penanganan yang baik di Indonesia. Penelitian ini bertujuan untuk mengetahui penerapan GMP dan SSOP pada proses pengolahan udang kupas mentah beku (peeled deveined). Metode dilakukan dengan observasi dan survei, dengan mengikuti secara langsung seluruh proses penerapan persyaratan kelayakan dasar (GMP, SSOP), mulai dari penerimaan bahan baku hingga pemuatan, dengan melakukan pengujian terhadap  mutu (organoleptik, mikrobiologi, antibiotik), pengamatan penerapan rantai dingin, rendemen, dan produktivitas tenaga kerja.  Analisa data dilakukan dengan  deskriptif. Hasil penelitian menunjukkan bahwa penerapan kelayakan dasar GMP dan SSOP sudah dilakukan dengan baik sesuai SNI No. 3457-2014 tentang udang kupas mentah beku.  Hasil pengujian mutu organoleptik bahan baku dan produk akhir adalah 8, uji mikrobiologi berkisar 9 x 103 kol/gr  - 2,5 x 103 kol/gr dan not detected  untuk hasil uji antibiotik,  sesuai dengan SNI. Penerapan rantai dingin telah dilakukan dengan baik dengan suhu udang bahan baku 3º C. Rendemen  pada potong kepala dengan dan pengupasan kulit rata-rata 69,8 % dan 81,1 %  sesuai dengan standar perusahaan. Produktivitas pada proses pemotongan kepala dan pengupasan adalah   37,1  dan 7,75 kg/jam/orang, sesuai dengan standar perusahaan.
STUDI KESESUAIAN KUALITAS AIR UNTUK BUDIDAYA IKAN LELE DUMBO (Clarias gariepinus) DI KAMPUNG LAUK KABUPATEN BANDUNG
Authors: Kelana Perdana Putra , Subhan Ujang , Suryadi Ibnu Bangkit Biosina , Haris Rangga Bayu Kusuma
Published: February 2022

Kampung lauk in Bandung district is one of the efforts to increase the production of catfish (Clarias gariepinus). The purpose of this study was to determine the suitability of water quality for catfish cultivation in Bandung district. The Method used in this study was a survey method with purposive sampling technique to determine the point of observation and water sampling. This study was carried out in 3 stations which were potential locations for the lauk village with 2 sampling points at each station. Parameters observed were temperature, dissolved oxygen, pH and ammonia in accordance with the parameters listed in SNI 01-6484.5: 2002 Catfish (Clarias gariepinus) Rearing Class. Based on observations, the average value of all parameters at all stations is in accordance with SNI 01-6484.5: 2002, except for pH at station 2. Based on this, stations 1 and 3 are suitable for catfish cultivation, station 2 is not suitable.
PSICODRAMATISTA EN FORMACIÓN EN SU DEVENIR QUIRÓN: SANADORA HERIDA
Authors: Manrique María Soledad , Stefani Graciela
Published: February 2022

RESUMEN El tema del trabajo es la dinámica del proceso de transformación de una psicodramatista en formación, sus dificultades y los recursos puestos en juego para sortearlas. Desde el marco epistemológico y metodológico del enfoque clínico se diseñó un estudio de caso que involucra el análisis inductivo sobre 10 encuentros psicodramáticos coordinados por ella y una compañera, las 9 resonancias escritas por la propia psicodramatista en formación luego de cada encuentro, 10 supervisiones posteriores a cada encuentro y 3 entrevistas en profundidad. La teoría Jungiana sirve como base para la interpretación de la dinámica del proceso, permitiendo analizar el recorrido de la psicodramatista a través de la activación de ciertos arquetipos, su simbolización y su progresiva integración.
NARRATIVAS DE PSICODRAMATISTAS NO PALCO DO SISTEMA ÚNICO DE ASSISTÊNCIA SOCIAL
Authors: Tófano Deiverson Jésus Abreu , Romagnoli Roberta Carvalho
Published: February 2022

RESUMO O presente artigo tem como objetivo apresentar a pesquisa de mestrado que buscou analisar, por meio de narrativas de psicodramatistas, a aplicabilidade e impressões da metodologia criativa do psicodrama dentro da perspectiva das oficinas do Serviço de Proteção e Atendimento Integral à Família (PAIF) no âmbito do Sistema Único da Assistência Social (SUAS). A pesquisa foi feita com oito psicodramatistas de quatro estados brasileiros diferentes através de entrevistas narrativas. Os resultados revelam repercussões positivas do uso do psicodrama com grupos, bem como desafios de seu fomento e aceitação no campo da assistência social. Conclui-se que o Psicodrama é um caminho de intervenção de grupos para o profissional socioassistencial que almeja por uma transformação no âmbito social e pessoal dos usuários-protagonistas.
O LUGAR DO DESEJO NA MATRIZ DE IDENTIDADE
Authors: Fonseca José
Published: February 2022

RESUMO O texto considera as raízes etimológicas da palavra “desejo”. Discute abordagens filosóficas do conceito e expõe contribuições psicanalíticas. Destaca o lugar do desejo dentro da concepção relacional de Moreno, dando ênfase à matriz de identidade. Leva em conta o desejo e suas circunstâncias: o desejo e a memória, o desejo e a linguagem, o desejo e a demanda, o desejo e a falta, o desejo e a dependência. Discutem-se as implicações, do ponto de vista terapêutico, de trazer à consciência os elementos inconscientes do desejo. Isso facilitaria ao sujeito desatar os seus nós e redirecionar suas demandas.
TEMPO E ESPAÇO DA DISCIPLINA DE DIDÁTICA NOS CURSOS DE PEDAGOGIA
Authors: Romanowski Joana Paulin , Domit Juliana
Published: February 2022

O objeto do estudo se refere ao tempo e espaço da disciplina de Didática nos cursos de Licenciatura em Pedagogia no Brasil. O problema investigado toma como questão principal: o tempo e espaço da disciplina de Didática nos cursos de pedagogia favorece a formação docente? O objetivo geral é compreender o tempo e espaço da disciplina de didática na formação inicial de professores no curso de Pedagogia. O pressuposto entende a disciplina de Didática, de natureza pedagógica, comprometida com as questões concretas da docência se constitui eixo central para os cursos de formação inicial de professores. A escolha da licenciatura em Pedagogia é intencional por ser este curso destinado à formação de professores para os anos iniciais do ensino fundamental e educação infantil. Metodologicamente o estudo assume a abordagem cartográfica (ROSÁRIO, 2008), a partir do mapeamento do curso de Pedagogia nas universidades federais brasileiras. Para a realização do estudo foi feita a leitura das matrizes curriculares de 61 cursos e a leitura dos Projetos Políticos Pedagógicos (PPPs). Os aportes teóricos fundamentam-se em Candau (1984), Gatti (2019), Marins (2015), Martins (2009,2012), Romanowski (2010,2016) e Veiga (1994, 2012). Os dados levantados permitem considerar que a disciplina de Didática está presente em todos os cursos de Pedagogia nas universidades federais brasileiras. A pesquisa reconheceu que há três eixos de disciplinas de didática nas propostas do curso: a Didática Geral, as Didáticas Específicas e as Didáticas para as modalidades de ensino.
METAPESQUISA: A IMPLEMENTAÇÃO DE POLÍTICAS PÚBLICAS EDUCACIONAIS NO CAMPO DA EDUCAÇÃO
Authors: Muylaert Naira , Oliveira Ana Cristina Prado , Costa Paula Araujo da
Published: February 2022

O trabalho tem como objetivo fazer uma análise dos referenciais teóricos e conceitos analíticos (denominados de descritores) mobilizados pelos estudos sobre implementação de políticas públicas no campo da Educação. O estudo parte da hipótese de que a produção acadêmica sobre o tema da implementação, no campo da Educação, é escassa. Para testar esta hipótese, realizamos uma metapesquisa a partir da definição de alguns descritores e teóricos de referências do campo da Ciência Política, para o levantamento da produção acadêmica – teses, dissertações e artigos – no campo da Educação nos anos de 2018 e 2019. No total, identificamos 10 artigos e 25 teses e dissertações que mobilizam conceitos e referenciais sobre o tema da implementação sendo que entre as teses e dissertações há uma maior concentração de estudos sobre os agentes implementadores e, dentre os artigos, uma maior concentração de estudos sobre estruturas de governança. A partir dos resultados, consideramos que há uma aproximação “em construção” à literatura específica do campo da Ciência Política, sobre implementação, pelos pesquisadores da área educacional. Ademais, como em outros estudos que envolvem levantamentos bibliográficos, reconhecemos que os resultados encontrados se limitam aos critérios de seleção e referencial de categorização definidos pelas autoras e que, ainda que possam não expressar uma generalização das tendências da produção acadêmica sobre implementação de políticas educacionais, seus resultados lançam luz para um campo ainda pouco explorado.
Flood plans in England
Authors: Brown Alan , Courtnadge Andy , Gosden John
Published: February 2022

This paper describes key issues relating to the Ministerial Direction to prepare flood plans, issued in April 2021, and how and why the interpretation of the authors differs from that of the Environment Agency Reservoir Safety Team.
Simulative Bewertung der Aerosol- und Humanemissionsbelastung
Authors:   Fraunhofer-Institut für Bauphysik, Valley, Norrefeldt Victor , Grün Gunnar ,   Fraunhofer-Institut für Bauphysik, Valley, Pathak Arnav ,   Fraunhofer-Institut für Bauphysik, Valley
Published: February 2022

Die Indoor Environment Simulation Suite ist ein Werkzeugkasten verschiedener Teilmodelle für die schnelle Simulation des Raumklimas. Herzstück dieser Toolbox ist das Velocity Propagating Zonal Modell (VEPZO), eine in vielen Fällen bezüglich der Abwägung zwischen Aufwand und Detailgrad des Ergebnisses überlegene Alternative zu aufwändig berechneten CFD-Simulationen. Aufgrund der Temperatur- und Luftstromverteilung kann mithilfe dieses Modells die Ausbreitung von Aerosolen und anderer Luftbestandteile in geschlossenen Räumen vorhergesagt werden.
Berufsbild Arbeitsmediziner
Authors:   Österreichische Akademie für Arbeitsmedizin und Prävention (AAMP), Wien, Hochgatterer Karl , Eckler Ursula ,   Bereich Lehre und Forschung, FH Campus Wien, Höltl Eva ,   Gesundheitszentrum der Erste Bank AG, Wien, Koth Stefan ,   Österreichische Akademie für Arbeitsmedizin und Prävention (AAMP), Wien, Letzel Stephan ,   Institut für Arbeits-, Sozial- und Umweltmedizin, Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Popper Yvonne ,   Stabsstellenleitung Arbeitnehmerschutz, Wiener Linien GmbH & Co KG, Wien, Pospischil Erich ,   Österreichische Gesellschaft für Arbeitsmedizin, ÖGA, Schunder-Tatzber Susanne ,   Head of Corporate Health Management, OMV AG, Wultsch Georg ,   Arbeitsmedizinisches Zentrum Graz
Published: February 2022

Mit dem dynamischen Wandel der Arbeitswelt ändern sich auch die Anforderungen an Beruf und Rolle von Arbeitsmedizinern1. Die Österreichische Akademie für Arbeitsmedizin und Prävention (AAMP) hat ein zeitgemäßes Berufsbild formuliert, das den geänderten Rahmenbedingungen Rechnung trägt. In Anlehnung an gängige Rollenmodelle macht es die Kernkompetenzen von Arbeitsmedizinern in kompakter Weise sichtbar. Damit bietet es Berufsinteressentierten einen Überblick über die beruflichen Möglichkeiten sowie Kunden der Arbeitsmedizin Orientierung für die erwartbaren Dienstleistungen.
Pharmakologisches Neuroenhancement in der Arbeitswelt. Sensible Themen valide erheben
Authors:   Institut für Arbeits-, Sozial- und Umweltmedizin Universitätsmedizin der Johannes Gutenberg-Universität Mainz, Dietz Pavel
Published: February 2022

Der folgende Beitrag geht auf die Problematik bei der Erhebung sensibler Fragen ein. Am Beispiel des pharmakologischen Neuroenhancements in der Arbeitswelt wird eine Einführung in indirekte Befragungstechniken gegeben und erste empirische Befunde unter Verwendung dieser Verfahren präsentiert.
İnsansız hava aracı temelli bir otomatikleştirilmiş stok sayım sistemi tasarımı
Authors: GÜMÜŞBOĞA İlkay
Published: February 2022

Birçok işletme ihtiyaç duyduğu ürünlerin tedariki için düzenli stok sayımı yapar. Maalesef bu sayım, çoğu işletmede eski usul, elle sayım şeklinde yapılır. Bu süreç, zaman alıcı, maliyeti yüksek ve hatta tehlikelidir. İşletmelerin stok kontrolünü sistematik hale getiren bir stok yönetim yazılımı olsa bile, stok verisi insanlar tarafından girildiği için ve genelde süreç, önce elle sayım yapılıp sonra verilerin sisteme işlenmesi şeklinde işlediği için hatalar olabilmektedir. Bu bağlamda, stok sayımı otomatikleştirilmeli, gerçek zamanlı, efektif ve güvenli olmalıdır. Bu çalışma kapsamında, iç ortamda çalışabilecek insansız hava aracı (İHA) tabanlı bir otomatik stok sayım sistemi önerilmiştir. Bu sistem, iç ortam konumlama problemini ultra geniş bant tabanlı bir konumlama sistemi ile santimetreler mertebesinde hassas bir şekilde çözer. Ayrıca, İHA üzerindeki lazer uzaklık ölçer (LiDAR) kullanılarak engelden sakınma fonksiyonu ile depo ortamlarında güvenli bir şeklide çalışır. İHA, otonom bir şekilde depo ortamında hareket ederken kamera vasıtası ile aldığı görüntü verisi, çevirim içi olarak işlenir ve stok sayımı süreci işletilir. Önerilen bu sistem için bir prototip tasarlanmış ve laboratuvar ortamında kurulan bir stok sayımı test alanında deneysel çalışmalar yürütülmüştür. Yapılan deneysel çalışmalar, burada önerilen İHA tabanlı otomatik stok sayım sistemin; iç ortam konumlama, engelden sakınma ve nihai olarak otonom stok sayım fonksiyonlarının başarılı bir şekilde çalıştığını göstermektedir.
Ballet «Queen Of Spades» by G. I. Banshchikov (to the Problem of Artistic Interpretation of the Story of A. S. Pushkin)
Authors:   Dmitry Hvorostovsky Siberian State Academy of Arts, Kholodova Maria V.
Published: February 2022

The focus of the article is the ballet «Lady Peak» by the modern St. Petersburg composer Gennady Ivanovich Banshchikov, which is an original artistic interpretation of the story of the Russian writer Alexander Sergeyevich Pushkin «Queen of Spades». The relevance of the study is that, on the one hand, the composer’s creative heritage has not yet received a comprehensive understanding in musicology, many compositions are waiting for their researcher. On the other hand, the performance of G. Banshchikov presents an original interpretation of the semantic ideas laid down by the genius of the word in the story. The analysis of the ballet revealed the specifics of the author’s reading, which consists in the implementation at all levels of drama of the card atmosphere, the generation of which was Pushkin’s «Queen of Spades». The results of the study make it possible to attribute the ballet of G. Banshchikov to one of the bright artistic peaks in the history of musical and stage incarnations of the story. At the same time, through the prism of the literary source, the composer actualizes serious philosophical topics in «Queen of Spades», integrating into the leading trends in the development of domestic art of the late 20th century
Modelo econométrico para el análisis de la elección de modo de transporte en viajes domésticos: el rol de las variables latentes
Authors: Muñoz Hoyos Claudia Helena , Pineda Uribe Beatriz Elena , Gómez Margarita Rosa
Published: February 2022

Las percepciones de seguridad y comodidad relacionadas con viajar en bus o en avión pueden afectar las decisiones de elección de los pasajeros en viajes domésticos. En este artículo se incorporaron las variables latentes seguridad y comodidad dentro de los modelos econométricos para estudiar la elección del modo de transporte para pasajeros que viajan en el trayecto Medellín-Barranquilla. En el modelo calibrado se incluyeron variables asociadas al modo de transporte, como el costo, el tiempo de viaje y las frecuencias, además de las variables de percepción. El modelo de elección discreta con variables latentes (VLs) se estimó secuencialmente: en primer lugar, se obtuvieron los parámetros del modelo de múltiples indicadores múltiples causas (MIMIC) y —posteriormente— se calibró el modelo híbrido de elección. El modelo calibrado permitió identificar las variables que inciden en la elección del modo de transporte aéreo o terrestre. Los resultados obtenidos son una herramienta eficaz en la toma de decisiones para las empresas que operan en cada uno de los modos.
Resistencia y violencia política en la postdictadura chilena: el caso de Osorno, 1990-1994
Authors: Sepúlveda Chávez Miguel
Published: February 2022

Este artículo explora las estrategias de resistencia y, en particular, las acciones de violencia política desarrolladas en la ciudad de Osorno durante los primeros años del periodo postdictatorial (1990-1994). Toma como fuente principal la prensa local y algunas entrevistas. Este trabajo da cuenta de la existencia de acciones de violencia política, así como sus principales características, en el marco de un proceso de resistencia desarrollado en Osorno, pese a un contexto adverso influenciado por elementos históricos, políticos y sociales de carácter tanto nacional como local.
On the Development of a Module for Working with the buoyantSimpleFoam Solver and the postProcess Utility of the OpenFOAM Platform
Authors:   South Urals Federal Research Centre of Mineralogy and Geoecology of the UB RAS, Chelyabinsk Region, Miass, Ilmen reserve, 456317, Russian Federation, Chitalov D. I.
Published: February 2022

The paper summarizes the results of research on the development of a software module that expands the source code of the OpenFOAM platform in terms of providing a specialist with access to new possibilities of a numerical ex­periment in relation to problems of continuum mechanics. The module provides the user with graphical and software tools for working with the buoyantSimpleFoam solver and postProcess utility. This work contains a description of the shortcomings of existing software solutions - analogs, the urgency of the problem under study is formulated. The author has set goals and defined the tasks necessary to achieve them. A description of the operation of the postProcess utility and the buoyantSimpleFoam solver is given, as well as the structure and parameters of the corresponding dictionary files of the design case. The author presents a set of technologies necessary for the implementation of the capabilities of a software module, typing, debugging and testing its program code. The performance of the developed software solution has been tested on the example of one of the fundamental problems of continuum mechanics, and the results of testing are presented. Based on the results of the study, the final conclusions are presented, as well as information on the scientific novelty and potential practical significance of the study.
Same Same but Different? Gender Politics and (Trans-)National Value Contestation in Europe on Twitter
Authors: Wallaschek Stefan , Kaushik Kavyanjali , Verbalyte Monika , Sojka Aleksandra , Sorci Giuliana , Trenz Hans-Jörg , Eigmüller Monika
Published: February 2022

The progress achieved in women’s rights and gender equality has become the target of a backlash driven by “anti-gender” activists and right-wing populists across EU member states. To a large extent, this conflict takes place in the digital and social media spheres, illustrating the new mediatized logic of value contestation. Therefore, we ask to what extent are the debates about gender equality on Twitter similar in three European countries, and how do users engage in these debates? We examine these questions by collecting Twitter data around the 2021 International Women’s Day in Germany, Italy, and Poland. First, we show that the debate remains nationally segmented and is predominantly supportive of gender equality. While citizens engage with the gender equality value online, they do so in a prevailingly acclamatory fashion. In contrast, political and societal actors show higher levels of engagement with the value and receive more interactions on Twitter. Our study highlights the relevance of national contexts to the analysis of (transnational) social media debates and the limited political engagement of citizens on Twitter across Europe. We also critically discuss the strengths and weaknesses of a cross-country social media comparison.
Characterization of adenylating enzymes and domain interactions involved in insect and bacterial non-ribosomal peptide synthesis
Authors:   , Platt Amanda Jo , Beld Joris
Published: February 2022

Non-ribosomal peptide synthetases (NRPSs) are responsible for full or partial biosynthesis of medically invaluable compounds including antifungals, immunosuppressants, and antibiotics like vancomycin. Synthetases have a modular architecture and function in an assembly line manner where peptide products are extended and modified as they are passed between modules. Engineering synthetases by replacing or re-ordering modules is an attractive strategy to generate "unnatural natural products". However, successful combinatorial engineering requires characterization of new NRPS domains and an improved understanding of the protein-protein interactions that govern synthetase function. This work focused on determining domain composition and substrate specificity of three-domain synthetases from bacterial species Lactobacillus iners and Scytonema hofmannii. Sequence analysis predicted the bacterial synthetases to contain adenylation- and carrier protein-domains, as well as C-terminal domains with hypothetical functions. We adopted a recently published mass spectrometry method to probe substrate specificity of these A-domains and they were shown to activate proline and glycine. Sequence homology between bacterial three-domain NRPSs and the Drosophila melanogaster Ebony synthetase, led us to interrogate Ebony in more detail and we focused on protein-protein interactions between domains within the synthetase. Dissection of the synthetase into separate proteins showed that certain combinations failed to produce product, but nine percent of activity was preserved following dissection of Ebony into a di-domain with detached C-terminal domain. Collectively, this work contributes to NRPS engineering efforts by characterizing the specificity of new domains and developing a platform to assess activity of a dissected synthetase. This information can be leveraged to utilize three-domain synthetases as engineering tools to characterize additional domains and generate new dipeptides.
Investigating microglial innate immune responses to amyloid-beta (1-42) and murine betacoronavirus (MHV-A59)
Authors:   , Cipollini Olivia Qiaofen , Krebs Fred C
Published: February 2022

Microglia are resident innate immune cells of the central nervous system (CNS) that sense pathogen-associated molecular pattern (PAMPs) and damage associated molecular patterns (DAMPs) during both infectious and sterile insults. Although toll like receptors (TLRs) play key roles in microglia responses by promoting tissue repair and contributing to CNS homeostasis, TLRs deregulation may mediate chronic inflammation contributing to neurodegeneration. Amyloid-beta (A[beta]) is an antimicrobial peptide protein that accumulates in senile plaques, a hallmark of Alzheimer's disease (AD). Microglia recognize and phagocytose A[beta], which activate the cell and result in a proinflammatory response. The role of TLRs in the response to A[beta] is ill defined. TLR2 and TLR4 sense lipopeptides and LPS, respectively, and have been involved in AD pathogenesis. Recently, upregulation of the expression of the double-stranded dsRNA sensor TLR3 was reported in AD human brains. However, whether TLR3 is activated in AD brains remains undefined. In Aim 1 studies, we test the hypothesis that A[beta]1-42 stimulation induces TLR3 activation in murine microglia. In Aim 2 studies, we investigated microglial TLRs responses to murine betacoronavirus mouse hepatitis virus (MHV)-A59, a neurotropic positive RNA virus that induces neuroinflammation and chronic demyelination. Interestingly, our findings demonstrated that microglia uptake of A[beta](1-42) induced phosphorylation of TLR3 at residue Y759, the hallmark of the TLR3 pathway activation. Moreover, we found that immune responses to MHV-A59 rely upon TLR signaling, which varies depending on the pathway activated. Our results highlight TLR3 activation as a novel response to A[beta](1-42) stimulation, and identify the TLRs sensing [beta]CoV infection in microglia.
Detección automática de diferencias entre imágenes para estimación de la irritación de productos mediante HET-CAM
Authors: Pérez Muñoz Ignacio , Sánchez Salmerón Antonio José
Published: February 2022

HET-CAM es una técnica in vitro utilizada para realizar una estimación de la irritación ocular que producirá cualquier sustancia química, o mezcla de ellas, en el ojo (mucosas) humano. Esta técnica, se basa en el análisis manual de los cambios producidos en las venas en distintos instantes de tiempo tras la aplicación de un producto sobre la membrana de un huevo fecundado. Dicho análisis se lleva a cabo por un experto que debe re- visar y apuntar durante un periodo determinado de tiempo los cambios que hayan ocurrido. Con el fin de automatizar este proceso, en este trabajo se propone una primera aproximación a la detección automática de los cambios en la distribución de la sangre producidos en el huevo. En concreto, se proponen técnicas de procesado y segmentación de las imágenes que facilitan el proceso de monitorización realizado por los expertos.