bluuebunny/crossref_metadata_2025 huggingface dataset:
Direitos humanos e discriminação: conceções de estudantes futuros profissionais de educação
Authors: Ferreira Isabel Maria Esteves Silva , Carvalho Luisa Maria Serrano de , Marchão Amélia de Jesus Gandum
Published: March 2023

A  Estratégia Nacional de Educação para o Desenvolvimento (PORTUGAL, 2018) acompanha a Agenda 2030 (UNITED NATIONS, 2015), sob o lema “Transformar o nosso mundo, não deixar ninguém para trás”. Uma sociedade que procura soluções para as  problemáticas sociais assume  a Educação para o Desenvolvimento, pela sua prática comprometida com o respeito pelos direitos humanos, contra a discriminação, face a acontecimentos que põem em risco o direito à liberdade, à justiça e à paz, promovendo o desenvolvimento integral. Considerando a estratégia supracitada, foi realizado um estudo no qual se assumiu como objetivo geral conhecer as conceções de estudantes que frequentam cursos na fileira da formação de educadores/professores, sobre diferentes temáticas inscritas na educação para o desenvolvimento, com particular incidência nos direitos humanos e na discriminação. Construiu-se, para o efeito, um questionário com questões abertas e fechadas, sendo os dados objeto de análise quantitativa (Statistical Package for the Social Sciences) e qualitativa (análise de conteúdo). Verifica-se que a maioria dos participantes se identificou com as duas temáticas, destacando contextos formais e não formais, nos quais tomaram contato com as mesmas. Os resultados conduzem ao questionamento sobre o  papel das instituições de ensino superior enquanto promotoras de uma reflexão critíca e participativa sobre aos direitos humanos e a não discriminação. A educação para os direitos humanos é crucial uma vez que todas as pessoas têm responsabilidade na defesa dos seus direitos e dos seus deveres enquanto seres humanos.
Análise prototípica das representações sociais de egressos da escola normal de Vitória da Conquista – BA
Authors: Rocha Alan de Aquino
Published: March 2023

Este artigo buscou apreender o núcleo central (NC) e o sistema periférico (ABRIC, 1988) das representações sociais (MOSCOVICI, 2012) de egressos, sobre a escola Normal de Vitória da Conquista – BA, com o intuito de contribuir com orientação de práticas pedagógicas e construção de saberes nos processos formativos. Participaram do estudo 10 ex-estudantes. A produção de informações foi realizada através de entrevistas realizadas pela Plataforma Google Meet, entre os meses de outubro de dezembro de 2021. Foram utilizados dois instrumentos para produção das informações: a técnica de associação livre de palavras (TALP), cujo tema indutor foi ‘Escola Normal’, sendo-lhes solicitado que registrassem as primeiras cinco palavras que lhes viessem à lembrança, e um questionário semiestruturado. As palavras evocadas passaram por análise prototípica utilizando o software IRAMUTEQ. Os achados apontam a palavra ‘amizade’, como sendo o núcleo central das representações, e a palavra ‘profissão’, constituindo o sistema periférico. A saliência desta representação permite afirmar o alto grau de afetividade atribuído à instituição de ensino por parte dos seus atores, atribuindo àquele espaço representacional um lugar de estabelecimento de vínculos de amizade, sobrepondo-se a aspectos mais formais. E a presença da palavra ‘profissão’ no sistema periférico, destaca a importância da escola na escolha de suas profissões, pois, dos 10 participantes, 6 seguiram na carreira docente.
Parameter Estimation and Estimability Analysis in Pharmaceutical Models with Uncertain Inputs
Authors: Moshiritabrizi Iman , Abdi Kaveh , McMullen Jonathan , Wyvratt Brian , McAuley Kimberley
Published: March 2023

A methodology is proposed to aid parameter estimation in fundamental
models of pharmaceutical processes. This methodology addresses
situations with insufficient data to reliably estimate all parameters,
when the estimation is complicated by uncertain independent variables.
The proposed method uses an augmented sensitivity matrix to rank the
combined set of parameters and uncertain inputs from most estimable to
least estimable. An updated mean-squared-error criterion is then used to
determine the appropriate parameters and inputs that should be
estimated, based on the ranked list. A model for one step in a batch
pharmaceutical production process with an uncertain initial reactant
concentration is used to illustrate the method, revealing that the
initial reactant concentration in each batch should be estimated along
with three out of six model parameters. Non-estimable parameters are
fixed at their initial values to prevent overfitting. The method will
aid error-in-variables parameter estimation in many situations involving
limited data.
Native Capillary Electrophoresis-Mass Spectrometry for Protein analysis: Current Progress and Perspectives
Authors: Schwenzer Ann-Katrin , Kruse Lena , Jooß Kevin , Neusüß Christian
Published: March 2023

Native mass spectrometry is a rapidly emerging technique for fast and
sensitive structural analysis of protein constructs, maintaining the
protein higher order structure. The coupling with electromigrative
separation techniques under native conditions enables the
characterization of proteoforms and highly complex protein mixtures. In
this review, we present an overview of current native CE-MS technology.
First, the status of native separation conditions is described for
capillary zone electrophoresis (CZE), affinity capillary electrophoresis
(ACE), and capillary isoelectric focusing (CIEF), as well as their
chip-based formats, including essential parameters such as electrolyte
composition and capillary coatings. Further, conditions required for
native ESI-MS of (large) protein constructs, including instrumental
parameters of QTOF and Orbitrap systems, as well as requirements for
native CE-MS interfacing are presented. On this basis, methods and
applications of the different modes of native CE-MS are summarized and
discussed in the context of biological, medical, and biopharmaceutical
questions. Finally, key achievements are highlighted and concluded,
while remaining challenges are pointed out.
Recent Progress and Prospects of Pitch-based Carbon Anodes for Alkali Metal-ion (Li/Na/K) Batteries
Authors: Jiang Ye , Jiang Jiangmin , Nie Ping , Guo Weijia , Chao Geng , Sun Zongfu , Fei Yi , Chen Yaxin , Zhuang Qaunchao , Xing Zheng , Ju Zhicheng , shao H
Published: March 2023

Pitch-based carbon materials (PBCMs) are regarded as one of the most
promising anodes used for alkali metal-ion (Li/Na/K) batteries due to
the advantages of their low cost, high carbon yield, abundant resource,
and environmental friendliness. However, PBCMs tend to be soft carbon
with small layer spacing at high temperatures, resulting in undesirable
reversible capacity and poor cycling stability during repeated charging
and discharging, which limit their future development and application in
energy storage systems. Up to now, many efforts are focused on the
modification of the PBCMs to achieve excellent alkali metal-ion storage
performance. In this review, the operation mechanisms and corresponding
microstructural characteristics of PBCMs used for alkali metal-ion
batteries are discussed. Moreover, the design and optimization
strategies of PBCMs are summarized and discussed in detail, including
structural adjustment strategy, heteroatom doping strategy, compound
modification strategy, pre-oxidation strategy, and coating strategy,
respectively. Furthermore, the research status and development prospects
of PBCMs are presented, as well as a perspective on future research
directions.
Ascaridia galli infection in chicken: Pathobiology and Immunological orchestra
Authors: Anisuzzaman * , Shohana Nusrat Nowrin , Rony Sharmin Aqter , Ali Md. Haydar , Hossain Md. Shahadat , Labony Sharmin Shahid , Dey Anita Rani , Farjana Thahsin , Alam Mohammad Zahangir , Alim Md. Abdul
Published: March 2023

Ascaridia galli is the largest gut-dwelling helminth of chickens
which confers adverse effects on meat and egg production and thus, on
the animal protein supply and the economy. Both adult and immature
parasites affect the gut health, but larval stages play the major role
in pathology. The larvae cause excessive mucus production, damage to the
intestinal gland, hemorrhage, anemia, diarrhea, and malnutrition. The
adult worms can cause death by intestinal obstruction and
intussusception. Although both cellular and humoral immunity are
involved in fighting against ascaridiasis, the role of naturally
acquired immunity is poorly defined. In cellular immunity, Th-2
cytokines (IL-4, IL-5, IL-9 and IL-13), goblet cells (mucin), GALTs (gut
-associated lymphoid tissues), CD8α+ intraepithelial cells, TCRγδ+T
cells, and TGF-β4 form a protective band. Type 2 immunity provides
protection by forming a network of eDAMP (endogenous damage-associated
molecular pattern), chitin, and parasitic antigens. Among antibodies,
IgY is the most prominent in chickens and provides temporary humoral
protection. During parasitic infection, infiltration of various immune
cells is evident, especially in the intestinal epithelium, lamina
propria, and crypts of the duodenum and jejunum. In chickens older than
3 months, gradual reduction of worm burden is more successful. Female
chickens exert a short-lived but higher level of protection by passing
IgY to chicks in the form of egg yolk antibodies (EAB). In laying
condition, immunity differs greatly between breeds. This review provides
a good overview of the silent but inevitable pathological changes
induced by A. galli; and the interaction of host immunity with
the parasite.
Gender roles at pig farming
Authors:   Faculty of Animal Science, Hasanuddin University,Jl. Perintis Kemerdekaan Km. 10 Makassar 90245 Sulawesi Selatan, Indonesia, Rindia Wati Ni Kadek , Amrawaty Andi Amidah ,   Faculty of Animal Science, Hasanuddin University,Jl. Perintis Kemerdekaan Km. 10 Makassar 90245 Sulawesi Selatan, Indonesia, Sri Lestari Veronica ,   Faculty of Animal Science, Hasanuddin University,Jl. Perintis Kemerdekaan Km. 10 Makassar 90245 Sulawesi Selatan, Indonesia
Published: March 2023

This study aim to determine the role of gender at pig farming in Poso Regency. This research was conducted from December 2021 to January 2022. The type of research used was descriptive research. The number of samples used in this study were 33 farmer families using a simple random sampling method by lottery. The data collection method used was by observation and interviews. Analysis of the data used was descriptive analysis. The research revealed that gender roles based on the aspect of male access dominated conducting counseling/training activities and accessing information. Gender roles based on control aspects were dominated by women and also shared. Gender roles based on aspects of decision-making were mostly done together and gender roles based on aspects of benefits, both men and women felt the same benefits from raising pigs.
Breeders' Perceptions of Cattle Aid from the Provincial Government of South Sulawesi
Authors:   Department of Socio Economics, Faculty of Animal Science, Hasanuddin University, Indonesia, Masse Anugrah Wijayanti , A Amrullah ,   Department of Socio Economics, Faculty of Animal Science, Hasanuddin University, Indonesia, Sirajuddin Sitti Nurani ,   Department of Socio Economics, Faculty of Animal Science, Hasanuddin University, Indonesia, Rasyid Ilham ,   Department of Socio Economics, Faculty of Animal Science, Hasanuddin University, Indonesia
Published: March 2023

Research on farmer-livestock groups' perceptions of cattle assistance from the Animal Husbandry and Animal Health Service of South Sulawesi Province in Soppeng Regency was carried out in February - March 2022. This location was chosen because Soppeng Regency is one of the areas that received cattle assistance programs from the Livestock and Animal Husbandry Office. Animal Health and success in the development of beef cattle population and also in Soppeng Regency has a very strategic beef cattle farming business development. This research uses descriptive quantitative research, which describes or illustrates the perception of farmers/breeders towards the cattle assistance program from the Department of Livestock and Animal Health of South Sulawesi Province in Soppeng Regency. The number of samples in this study were 42 farmers with deliberate sampling. Analysis of the data used is descriptive analysis using a Likert scale. Based on the results of research on farmer perceptions of the beef cattle assistance program provided by the government through the Animal Husbandry and Animal Health Service of South Sulawesi Province in Soppeng Regency, it was found that the perception of cattle farmers with indicators of farmer income, mindset, breeding methods, population increase, and quality livestock received by farmers are in the high category because they are more likely to agree with the beef cattle assistance program.
The relationship between maintenance waiting time and the selling price of striped buffalo at the Bolu Animal Market, North Toraja Regency
Authors:   Department of Socio Economics, Faculty of Animal Science, Hasanuddin University, Indonesia, A Yusri , Sirajuddin Sitti Nurani ,   Department of Socio Economics, Faculty of Animal Science, Hasanuddin University, Indonesia, Rasyid Ilham ,   Department of Socio Economics, Faculty of Animal Science, Hasanuddin University, Indonesia
Published: March 2023

This study was conducted to determine how the effect of waiting time on the sale of buffalo in Bolu Market, North Toraja Regency. This study uses an explanatory quantitative method which aims to explain the relationship between waiting time and the selling price of striped buffalo in the North Toraja sponge market. The population and sample in this study were 41 traders using non-probability sampling technique with the type used, namely saturated sampling or commonly referred to as a census. Analysis of the data used, namely the T test is used to test the hypothesis of the influence of individual independent variables on the dependent variable. The results of this study indicate that there is no effect of waiting time on the sale of buffalo at Bolu Market, North Toraja Regency, but is influenced by other factors such as skin color, horns, body posture and other factors
Corrigendum on: Effect of defective NPC three level inverter on nonlinear command of induction motor lesions [Serb. Jour. of Elect. Eng., Vol. 19, no. 2, june. 2022, pp. 167-192]
Authors: Editorial E
Published: March 2023

The authors of the paper entitled ?Effect of Defective NPC Three Level
Inverter on Nonlinear Command of Induction Motor?, Mendaz Kheira, Benhadda
Yamina, Bounoua Houria, informed the Editor about necessary correction of
the paper, as follows: Afiliation of the first author, Mendaz Kheira, should
be replaced by the text: Electrical engineering department, IRECOM
laboratory, Institute of Science and Technology Belhadj Bouchaib, University
Ain Temouchent, Algeria; Email: kheiramendez@gmail.com The authors apologize
for these changes.

 Link to the corrected article 10.2298/SJEE2202167K
Neurofibromatosis 1/Noonan syndrome associated with Hashimoto's thyroiditis and vitiligo
Authors: Yalcin B , Tamer E , Gür G , Oztas P , Polat MU , Alli N.
Published: March 2023

This article does not have an abstract.
Japanese cedar pollen as an exacerbation factor in atopic dermatitis: results of atopy patch testing and histological examination
Authors: Yokozeki H , Takayama K , Katayama I , Nishioka K.
Published: March 2023

Atopy patch testing with Japanese cedar pollen extract has been used to investigate patients with atopic dermatitis whose condition is exacerbated by contact with Japanese cedar pollen. Comparative atopy patch testing, scratch tests, and assays for total IgE and specific IgE were performed in 74 patients with atopic dermatitis, 5 patients with Japanese cedar pollinosis and 15 control subjects. A skin biopsy was performed on any sites that were positive to Japanese cedar pollen patch test. The results after 48 h of atopy patch testing were compared with the patient's history, skin scratch test and specific IgE. Twenty-two of the 74 patients (30%) had a history of exacerbation every spring after contact with Japanese cedar. Of these patients 68% showed a positive reaction to Japanese cedar pollen extract, as did 21% of patients with atopic dermatitis without a history of exacerbation by Japanese cedar pollen, 20% of patients with Japanese cedar pollinosis without eruption and 7% of control subjects. A histological examination revealed eczematous changes and infiltration of lymphocytes and eosinophils in atopy patch testing positive sites. In conclusion, atopy patch testing with Japanese cedar pollen extract is a useful method for investigating trigger factors for eczematous skin lesions in a subgroup of patients with atopic dermatitis.
Incontinentia pigmenti with associated lesions in two generations. Clinical, light microscopic, and electronmicroscopic examinations
Authors: Schmidt H. , Hvidberg-Hansen J. , Christensen HE.
Published: March 2023

No abstract available
Association between Retinal Vein Occlusion and Psoriasis in Korea: A Nationwide Population-based Prospective Cohort Study
Authors: Lee Seung Woo , Koo Ha Yeh Rin , Han Kyung Do , Lee Young Bok
Published: March 2023

Psoriasis is a chronic inflammatory skin disease imparting increased risk of cardiovascular diseases. Until now, few studies have reported an increased incidence of ophthalmological retinal vasculopathy in individuals with psoriasis. This study aimed to investigate the association between psoriasis and retinal vein occlusion in the Korean population. Data collected by the National Health Insurance Service between 2009 and 2015 in Korea were analysed. Participants who underwent national health examinations from 2009 to 2012 were enrolled in this study and were divided into either the psoriasis group (n = 3,088) or the control group (n = 465,205). All occurrences of retinal vein occlusion were observed, and the incidence rate of retinal vein occlusion was compared between the psoriasis and control groups. A Cox proportional hazards regression analysis was used to assess the association between psoriasis and newly developed retinal vein occlusion. During a mean 4.37-year follow-up period, 2,034 patients developed retinal vein occlusion. According to multivariable Cox proportional hazard models, individuals with psoriasis had a significantly higher risk of retinal vein occlusion compared with controls (hazard ratio 1.72, 95% confidence interval 1.18–2.51) after adjustments for covariates. This study found that psoriasis was positively associated with retinal vein occlusion.
ЕКОЛОГО-ГІГІЄНІЧНА ОЦІНКА НАДХОДЖЕННЯ НІТРАТІВ В ОРГАНІЗМ ЛЮДИНИ З ПИТНОЮ ВОДОЮ
Authors: Хоменко Олена , Кравченко Людмила Миколаївна , Жицька Людмила Іванівна , Бондаренко Юрій Григорович
Published: March 2023

В роботі піднімається питання відповідності води з джерел централізованого та децентралізованого водопостачання в Україні і Черкаській області вимогам ДСанПіНу 2.2.4-171-10 «Гігієнічні вимоги до питної води, призначеної для споживання людиною», Закону України «Про питну воду та питне водопостачання», «Про забезпечення санітарного та епідемічного благополуччя». Висвітлено результати дослідження вмісту нітратів у централізованих водогонах та приватних свердловинах і колодязях населених пунктів Черкаського району. Встановлено, що у воді централізованих джерел водопостачання середня концентрація нітратів становила 24 мг/дм3, що не перевищує гранично-допустимий норматив. Однак у 2,8 % досліджених проб води джерел централізованого водопостачання спостерігалося незначне перевищення нормативних значень, а у воді окремих джерел воно становило 110 мг/дм3 (м. Умань, м. Тальне та ін.). Визначена середня концентрація нітратів у воді децентралізованих джерел водопостачання становила 44 мг/дм3, що в межах гранично-допустимого рівня, але у 18 % досліджених проб має місце відхилення від допустимої добової дози (ДДД – 50 мг/дм3) в 1,5–4,0 рази, і в окремих джерелах контролю (шахтні та трубні колодязі), становить 235 мг/дм3 і навіть 900 мг/дм3, що надзвичайно небезпечно для здоров’я населення, особливо для немовлят, добова норма для яких становить 2,5 мг/кг/добу. Вивчено питання дії нітратних сполук на організм людини, які у високих дозах швидко окиснюють гемоглобін крові в метгемоглобін, викликаючи циркуляторну та тканинну гіпоксію, блокують ферментні системи клітин організму, що призводить до порушення окиснювального фосфорилювання і нітратної метгемоглобінемії. Визначено можливі джерела надходження токсикантів у питну воду, розроблено рекомендації щодо її використання.
PENINGKATAN HASIL BELAJAR MATERI PECAHAN MELALUI MEDIA VISUAL DI KELAS IV SEKOLAH DASAR
Authors: Aryanti Dewi
Published: March 2023

This study aims to determine whether or not there is an increase in mathematics learning outcomes using visual media about fractions of fourth grade elementary school students. This study uses a qualitative research method with a classroom action research approach. The subjects of the research were the fourth grade elementary school students, totaling 16 students, consisting of 9 male students and 7 female students. The object of this research is the result of learning mathematics about fractions through visual media. The data collection instrument used a formative test sheet. The results of this study indicate that in the first cycle the score is 65 with an average grade of 56 so that classical learning completeness is 44%, while in the second cycle the score is 65 with an average grade of 80 reaching 100%. Based on the data obtained and the analysis from cycle I to cycle II, student learning outcomes have increased by 56%. Thus, it can be concluded that there is an increase in mathematics learning outcomes in grade IV elementary school by using visual media
Challenging the Status Quo: Khaled M. Abou El Fadl’s Perspectives on Islamic Legal Authority and the Restrictive Fatwa on Women’s Solo Travel
Authors: Faiz Muhammad Fauzinudin , Rohmatulloh Dawam Multazamy , Solikhudin Muhammad
Published: March 2023

This article discusses Khaled M. Abou El Fadl’s (El Fadl) views on Islamic legal authority and his critique of the fatwa prohibiting women from travelling alone without a mahram (unmarriageable kin) issued by the Council for Scientific Research and Legal Opinions (CRLO). This research employs a literature review method by analysing several fatwas issued by the CRLO and several of El Fadl’s works as primary sources. The research findings indicate that El Fadl strives to formulate an authoritative and progressive Islamic law. El Fadl criticises the CRLO’s authoritarian fatwa regarding the prohibition of women travelling alone without a mahram using a hermeneutic framework. El Fadl emphasises that the reader must understand the message of the religious text by connecting the text at the time of its revelation with the current text, considering the text’s competence, meaning determination, and representation. According to El Fadl, the hadith text used as a basis by the CRLO is no longer relevant in the current context because the sense of security can be overcome on which the fatwa is based. The author argues that El Fadl’s views belong to progressive Muslim thinking. This article is expected to contribute to the discourse on openness and inclusivity in Islam.
Appropriate criteria for a transition from conventional to sustainable warehousing
Authors: VASILEVA Anita , LAZAREVSKA Ana M. , JAKIMOVSKA Kristina
Published: March 2023

This research paper conducts the process of selecting the criteria that are the most appropriate for a transition from conventional to sustainable warehousing. SWOT analysis is used to emphasise the weaknesses of conventional and the strengths of sustainable warehousing to select the most appropriate for the herein presented study. The results have been verified via a questionnaire filled out by professionals in economics, logistics and warehousing, and mechanical engineering. be added under the methodology section. The results gave the five most important criteria by transforming the conventional into sustainable warehousing. Finally, the paper concluded that renewable energy sources are the most important criteria for transforming by conventional to sustainable warehousing by environmental aspects, as well as the smart technology is above all other criteria by economic aspect. Moreover, providing personal protection equipment and servicing machinery and vehicle on regular basis are the two mainly criteria by social (safety) aspect.
Analyzing the energy analysis tool (The Autodesk Insight 360) of BIM during the early stages of the design process in terms of window factors in a single-family house
Authors: BOLOORCHI Fatemeh
Published: March 2023

In designing eco-buildings, windows play a big part in minimizing the energy load. There has not been any easy-to-use software to speed up the process, even after many recent studies about environment-friendly window size, shading, position, and material. Thus, a single-family house with simple geometry in Kvemelto karti, Georgia, was simulated to introduce an alternative method to manage this gap. A building information model (BIM) was devised for this procedure through Autodesk Revit® due to its simplicity, popularity, interoperability and convenience among its users. Not to mention, the energy analysis tool (The Autodesk Insight 360) in Revit (BEM) displays the total energy load while, in this case, focusing on window size, position, material, and shading executed by Autodesk Green Building Studio®. The early energy analysis (the optimum window-to-wall ratio (WWR), the windows’ location in the wall, material, and shading) suggested by BEM does not give enough information to apply in the early stages of design and create a net-zero-energy building. The aim is to show the gap between data-driven from BEM and design strategies and to display the information required to be more detailed. For this purpose, after using Insight 360 (a web-based tool) for investigating window shades, material, and WWR, it has been concluded that there is a need for a more convenient way to automate the process in more depth. They could help to pick a viable widow shading, size, position, and material. Besides, choosing determined factors using just BEM is not practical because detailed characteristics of window factors as determining elements are not defined. This tool has its limitations.
Cerebral vasculopathy after COVID-19 infection in the central region of Saudi Arabia: a case report
Authors: Alsudairi Hajar , Alharbi Seetah , Alamjir Mohammad , Elamin Rabeaa
Published: March 2023

Background: The most common symptoms of coronavirus disease 2019 (COVID-19) are dyspnea, fever, cough, headache, diarrhea, and myalgia.
Case Presentation: We report a case of peripheral cortical borderline cerebral vasculopathy associated with COVID-19 infection in a young female patient who presented with seizures and a history of acute confusion and generalized tonic-clonic seizure. She was diagnosed with COVID-19 disease 1 week ago before the presentation. Her illness was mild and did not require hospitalization. The magnetic resonance imaging study revealed cerebral vasculopathy. COVID-19 infection and other risk factors can increase the risk of cerebral vasculopathy. To our knowledge, no other case of peripheral cortical borderline cerebral vasculopathy associated with COVID-19 infection has been reported in Saudi Arabia.
Conclusion: This report highlights the importance of considering seizures and cerebral vasculopathy as manifestations of COVID-19 disease. Physicians should consider seizures due to cerebral vasculopathy among the expected neurological complications of COVID-19 to aid early detection and management of COVID-19- associated complications.
ЗАЛЕЖНІСТЬ СТРУКТУРИ ЗМАГАЛЬНОЇ ДІЯЛЬНОСТІ ЛЕГКОАТЛЕТІВ-СПРИНТЕРІВ ВІД РІВНЯ РОЗВИТКУ ОСНОВНИХ СТОРІН ЇХНЬОЇ СПЕЦІАЛЬНОЇ ПІДГОТОВЛЕНОСТІ
Authors: Савчук Сергій , Кирієнко Олександр , Безверхня Галина , Цибульська Вікторія
Published: March 2023

У статті здійснено кореляційний аналіз показників технічної та спеціальної підготовленості. Проаналізовано залежність між швидкістю бігу на основних відрізках змагальної дистанції (100 м) та показниками спеціальної силової підготовленості юних спринтерів, залежність між швидкістю бігу юних спринтерів на модельних відрізках дистанції 100 м та їх результатами у швидкісно-силових тестах, залежність між показниками проміжного часу на модельних відрізках дистанції 100 м та рівнем розвитку швидкісних якостей юних спринтерів. На основі аналізу науково-методичної літератури здійснено аналіз і порівняння розвитку швидкісно-силових здібностей юних легкоатлетів-спринтерів та стрибунів, визначено, що важливе місце у дослідженнях багатьох учених займає проблема технічної підготовки спринтерів, оскільки досягти високих результатів зможуть лише спортсмени, які оволоділи досконалою технікою виконання рухів.
El reciclaje inclusivo y el COVID-19. Respuesta regulatoria durante el primer confinamiento en el Ecuador
Authors: Martinez Moscoso Andrés , Vásquez-Salinas Bernarda , Sucozhanay Dolores , Vanegas Paúl
Published: March 2023

En la investigación se analizan datos cualitativos relacionados con la gestión integral de residuos sólidos, reciclaje inclusivo y COVID-19. Además, se estudia los resultados de la encuesta “Gestión de Residuos y Economía Circular” sobre la percepción de los ciudadanos frente al reciclaje y recicladores durante el primer confinamiento (marzo-septiembre 2020 Cantón Cuenca). Entre los principales hallazgos se identificó que las restricciones implementadas tuvieron un alto impacto en la labor de los recicladores y en el comportamiento ciudadano. Con relación a los recicladores únicamente se estableció un protocolo de retorno progresivo a sus actividades, no hubo apoyos focalizados, de lo que se desprende que se trata de un sector excluido de las políticas públicas. La encuesta a su vez evidencia que si bien la labor de los recicladores como actores de la economía informal contribuye al cuidado del medio ambiente su situación es precaria, riesgosa y poco reconocida por la colectividad.
A Man with Worsening Scaling Plaques and a New Onset Large Draining Ulcerated Tumor
Authors: Taylor Alexandra , Pile Hannah , Altman David
Published: March 2023

Mycosis Fungoides (MF) is the most common form of cutaneous T-cell lymphoma, a rare condition which typically presents with erythematous patches and plaques, skin nodules and/or tumors. Advanced disease may progress to a more aggressive form known as a large-cell transformation (LCT). MF may be easily confused for psoriasis, a deep fungal infection, and pyoderma gangrenosum. Psoriasis and MF share common features associated with the abnormal functioning of T cells, and in the absence of an infectious process, pyoderma gangrenosum (PG) may be considered. Definitive diagnosis relies upon histopathology revealing characteristic features of MF including cerebriform nuclei, intraepidermal Pautrier microabscesses, epidermotropism and haloed lymphocytes, ruling out the other etiologies. Here is a case of a 62-year-old male with an atypical case of MF with LCT who presented with worsening skin eruption and a large draining ulcerated abdominal plaque. MF is typically a slow and indolent disease with multiple treatment options. Brentuximab vedotin (BV) is a monoclonal antibody targeting the CD30 antigen on cancer cells and is increasingly used in the treatment of MF patients with LCT. The patient was referred to hematology/oncology where further workup revealed CD30 positive large T-cells. He was started on BV and has already shown signs of significant disease regression.
Parabolic equations of the fourth order with changing time direction with complete matrix of gluing conditions
Authors: Марков В.Г. , Попов С.В.
Published: March 2023

Устанавливается разрешимость краевых задач для параболических уравнений четвертого порядка с меняющимся направлением времени в случае полной матрицы условий склеивания. Известно, что в случае краевых задач для уравнений с меняющимся направлением времени гладкость начальных и граничных данных не обеспечивает принадлежность решения пространствам Гёльдера. С. А. Терсенов в простейших случаях получил необходимые и достаточные условия разрешимости таких задач для параболических уравнений второго порядка в пространствах $H^{p,p/2}_{x\,t}$ при p > 2. При этом условия разрешимости (ортогональности), которым должны удовлетворять данные задачи, были выписаны в явном виде. Отметим, что в одномерном случае число условий ортогональности конечно. В то же время в многомерном случае число условий ортогональности, интегрального характера, бесконечно. В работе показано, что гёльдеровские классы решений краевых задач для параболических уравнений четвертого порядка с меняющимся направлением времени, а также количество условий разрешимости, зависят от вида матрицы условий склеивания с действительными коэффициентами.

We study solvability of boundary value problems for the fourth order parabolic equations with changing time direction in case of complete matrix of gluing conditions. For boundary value problems for equations with changing time direction, the smoothness of the initial and boundary data does not guarantee that the solution belongs to a Holder space. In the simplest cases, S. A. Tersenov obtained necessary and sufficient conditions for solvability of such problems for second order parabolic equations in the spaces $H^{p,p/2}_{x\,t}$ for p > 2. Moreover, the solvability (orthogonality) condition was written in an explicit form. Note that in the one-dimensional case the number of orthogonality conditions is finite, while in the multidimensional case the number of orthogonality conditions of the integral character is infinite. We show that the Holder solution classes of boundary value problems for the fourth order parabolic equations with changing time direction, as well as the number of solvability conditions, depend on the form of the matrix of gluing conditions with real coefficients.
On solution to the simplest functional equation in curvilinear-band-type domain
Authors: Шайхуллина П.А.
Published: March 2023

Рассматривается функциональное уравнение $u(\xi + 1) − u(\xi) = d(\xi), ξ\in\Pi,$ в области $\Pi\subset C$ типа "криволинейная полоса". Для достаточно быстро убывающих на бесконечности и голоморфных внутри области $\Pi$ функций $d(\xi)$ показано существование голоморфного и ограниченного решения, исследован вопрос единственности. Получены точные оценки найденных решений и асимптотика.

We consider the functional equation $u(\xi + 1) − u(\xi) = d(\xi), ξ\in\Pi,$, in the region $\Pi\subset C$  of "curvilinear band" type. For sufficiently fast decreasing at infinity and holomorphic within the domain $\Pi$  functions $d(\xi)$ the existence of a holomorphic and bounded solution is shown, the uniqueness of the solutions is investigated. We also obtained precise estimates of the constructed solutions and its asymptotic behavior.
Comparing of some sensitivities for nonlinear models Comparing of some sensitivities (Greeks) for nonlinear models of option pricing with market illiquidity
Authors: Dyshaev M.M. , Fedorov V.E.
Published: March 2023

We discuss the numerical solving of nonlinear options pricing models to a market with the insufficient liquidity. Also for these models the sensitivity coefficients of the option price (Greeks) were found numerically. These nonlinear models were selected by us on the basis of our group classification of a general model and were previously obtained in the works of Frey and Stremme, Sircar and Papanicolaou, and Sch¨onbucher and Wilmott. The behavior of the price and its sensitivity coefficients in the nonlinear models and in the linear Black–Scholes model is compared. The results of the comparing presents in the form of graphs, a brief comparative analysis of them was made.
COMPACT FINITE ELEMENTS BASED ON MODIFIED EQUATIONS OF THE PLATE THEORY
Authors: Аннин Б.Д. , Волчков Ю.М.
Published: March 2023

В работе модифицированные уравнения упругого слоя используются для построения компактных конечных элементов, условия сопряжения между которыми формулируются в виде условий непрерывности усилий и моментов на их гранях. Предложенные конечные элементы можно эффективно использовать при численном решении задач о напряженно-деформированном состоянии слоистых конструкций, деформируемых тел, содержащих разрезы и трещины, поскольку компактные элементы являются естественными регуляризаторами в задачах, содержащих особенности в напряженном состоянии. Приведено сравнение результатов численного решения с аналитическим решением задачи об определении напряженно-деформированного состояния в окрестности вершины трещины, расположенной в упругой плоскости. Численное решение задачи получено с использованием итерационной процедуры самоуравновешенных невязок.

The modified equations of the elastic layer are used to construct compact finite elements, the conjugation conditions between which are formulated as conditions for the continuity of efforts and moments on their faces. The proposed finite elements can be effectively used in the numerical solution of problems of the stress-strain state of layered structures and deformed bodies containing cuts and cracks, since compact elements are natural regularizers in problems containing singularities in a stressed state. The paper compares the results of a numerical and analytical solutions to the problem of determining the stress-strain state in the vicinity of the crack tip located in the elastic plane. The numerical solution to the problem is obtained using the iterative procedure of self-balanced residuals.
Equilibrium problems for Kirchhoff–Love plates with nonpenetration conditions for known configurations of crack edges
Authors: Lazarev N.P. , Itou H.
Published: March 2023

The paper focuses on nonlinear problems describing the equilibrium of Kirchhoff–Love plates with cracks. We assume that under an appropriate load, plates have special deformations with previously known configurations of edges near a crack. Owing to this particular case, we propose two types of new nonpenetration conditions that allow us to more precisely describe the possibility of contact interaction of crack faces. These conditions correspond to two special cases of configurations of plate edges. In each case, the nonpenetration conditions are given in the form of a system of equalities and inequalities. For initial variational statements, we prove the existence and uniqueness of solutions in an appropriate Sobolev space. Assuming that the solutions are sufficiently smooth, we have found differential statements that are equivalent to the corresponding variational formulations. The relations of the obtained differential statements are compared with the well-known setting of an equilibrium problem for a Kirchhoff–Love plate with the general nonpenetration condition on crack faces.
ABOUT SOME CLASSES OF REVERSE TASKS ON DETERMINING THE SOURCE FUNCTION
Authors: Неустроева Л.В. , Пятков С.Г.
Published: March 2023

Рассмотрен вопрос о разрешимости, единственности и некоторых качественных свойствах решений обратных задач об определении точечных источников (правой части специального вида) в одномерном параболическом уравнении. В качестве данных переопределения взяты значения решения в некотором наборе точек. Приведены примеры, показывающие, что без дополнительных условий на взаимное расположение источников и точек измерений единственность может отсутствовать. Получена асимптотическая формула определения координат одного источника по двум замерам.

We examine the questions of solvability, uniqueness, and some qualitative properties of solutions of inverse problems of determining point sources (the right-hand side of a special form) in a one-dimensional parabolic equation. The values of the solution at a collection of points are taken as the overdetermination data. Examples are displayed showing that the uniqueness fails without additional conditions on the mutual location of sources and measurement points. An asymptotic formula for determining the coordinates of one source from two measurements is obtained.
Dynamic extracellular vestibule of human SERT: unveiling druggable potential with novel high-affinity allosteric inhibitors
Authors: Salomon Kristine , Abramyan Ara , Plenge Per , Wang Lingle , Bang-Andersen Benny , Loland Claus , Shi Lei
Published: March 2023

The serotonin transporter (SERT) tightly regulates synaptic serotonin levels and has been the primary target of antidepressants. Binding of inhibitors to the allosteric site of human SERT (hSERT) impedes the dissociation of antidepressants bound at the central site, and may enhance the efficacy of such antidepressants to potentially reduce their dosage and side effects. Here we report the discovery of a series of high-affinity allosteric inhibitors of hSERT in a novel scaffold, with the lead compound, Lu AF88273 (3-(1-(2-(1H-indol-3-yl)ethyl)piperidin-4-yl)-6-chloro-1H-indole), having 2.1 nM allosteric potency in inhibiting imipramine dissociation. In addition, we find that Lu AF88273 also inhibits the serotonin transport in a non-competitive manner. The binding pose of Lu AF88273 in the allosteric site of hSERT is determined with extensive molecular dynamics simulations and rigorous absolute binding free energy perturbation (FEP) calculations, which show a part of the compound occupies a dynamically formed small cavity. The predicted binding location and pose is validated by a site-directed mutagenesis study, and can explain much of the structure-activity relationship of these inhibitors using the relative binding FEP calculations. Together, our findings provide a promising lead compound and the structural basis for the development of allosteric drugs targeting hSERT. Further, they demonstrate that the divergent allosteric sites of neurotransmitter transporters can be selectively targeted.
DIREITO DE LIBERDADE DE EXPRESSÃO NA INTERNET COMO DIREITO FUNDAMENTAL: UM ESTUDO À LUZ DA TEORIA DE ROBERT ALEXY
Authors: Gontijo Ana Maria Lima Maciel Marques , De Oliveira Lucimara Aparecida Silva Antunes , Gontijo Vinícius José Marques
Published: March 2023

Como todo ambiente de interação e convivência, na internet, as pessoas exercem a liberdade de expressão, mas como é possível a convivência livre sem infringir os direitos dos demais? Pode o gestor ou provedor de sites retirar conteúdos ao seu arbítrio? Pelo método hipotético-dedutivo, faz-se  um estudo da liberdade de expressão na internet à luz da Teoria dos Direitos Fundamentais de Robert Alexy. Considerando-se a eficácia horizontal dos direitos fundamentais e a teoria do limite dos limites, conclui-se que restrições à liberdade de expressão devem ser de ordem constitucional ou em razão dela, o que deve ser analisado no caso concreto pelo julgador que sopesará os valores envolvidos, não tendo os administradores dos sites tal legitimidade.
Inflation rate and Poverty: Does Poor Become Poorer with Inflation?
Authors: Paul Mahua , Sharma Pooja
Published: March 2023

This paper examines the inflation rates for the period 2005–06 and 2011–12 and concludes that inflation in 2005-06 hurts the poor more since the rise in food prices was substantial in this period and food constitutes a substantial proportion of their total expenditure. The paper observes that there was a substantial rise in Inflation which was experienced in the food grains like egg, fish, and meat, while the growth of inflation rate was observed minimal in case of beverages, footwear, and edible oil.Further, the impact of inflation on poor varied not only across both rural and urban areas but also the impact was different for different time periods. The paper also depicts shifts in the pattern of inflation rate across the expenditure classes between 2005–06 and 2011–12 and establishes inverse association between inflation rate and expenditure in the year 2005-06 for both rural and urban areas while the relationship was completely distinct in case of 2011–12 for both rural and urban areas. The study clearly reveals that bottom thirty percent of the population in rural areas observes same inflation rate as their urban counterparts for the year 2005-06. Finally, the paper concludes that the impact of inflation is not only commodity specific but also decile class specific. Further, the impact of inflation is observed to be different for rural and urban areas. This establishes the role of policy and government intervention through the public distribution scheme favoring the poor section with the aim of minimizing the gap of the impact of inflation experienced by poor and rich.
An Empirical Research on Customers’ Awareness of E-Commerce in the Context of Vietnamese Developing Economies
Authors: Nguyen Nhu-Ty , Tran Thanh-Tuyen , Huynh Anh-Quan
Published: March 2023

Many research studies have been conducted in the field of e-commerce, which can contribute for academic background and development of e-commerce around the world. In Vietnam, the awareness of customers toward e-commerce is limited for the emerging of this industry in Vietnam recently. This study tries to figure out research model explains the factors and to study the awareness of customers that influence the behaviors and acceptance of users buying online in the developing economy. According to the research, buying online is quite risky. Therefore, product safety would be the purchasing decision's priority. Online sales providers need to provide a safe way of ensuring consumers ' purchasing process. Through hard qualification process, they need to shortlist the good quality product. The sale would grow dramatically as consumers gained confidence. Not only should they care about the short-term profit in order to get the products of low quality.
Economic Impact of the Eel. Eel (Anguilla Bicolor) Aquaculture on Local Communities in Banyuwangi Regency
Authors: Osmaleli Osmaleli
Published: March 2023

Aquaculture in Indonesia has several superior commodities, one of which is eel. Eel (Anguilla bicolor) is a fish with high economic value and a type of fish that is an export commodity (Japan, Hong Kong, Germany, Italy, and several other countries). This condition is inversely proportional to the level of domestic eel consumption which is still relatively low. Aquaculture activities provide direct and indirect impacts on the local society, one of them is the economic impact of the existence of giant mottled eel aquaculture in the Banyuwangi District. The research aimed to analyze the economic impact of giant mottled eel aquaculture activities. The Survey research method was used and data were analyzed using descriptive and multiplier effect analysis. The research result of the economic impacts of giant mottled eel aquaculture that provides a positive economic impact on local society is indicated by the development of giant mottled eel aquaculture activities and the other sectors. Keynesian Local Income Multiplier value was 2.65. Type I Multiplier Income Ratio was 1.16 and Type II Multiplier Income Ratio was 1.6.
The Role of Internal Audit in Risk Management in Bandung Amil Zakat Institutios (LAZ) in The Era of Covid-19 Pandemic
Authors: Maemunah Mey , Hernawati Nopi , Kuntorini Ririn Sri
Published: March 2023

Abstract. This study aims to analyze the role of internal audit in risk management in the amil zakat institution (LAZ) in the city of Bandung. This study uses descriptive analysis with data collection techniques using primary data obtained from observations, interviews and documentation from related parties. The results of the analysis prove that the amil zakat institution in Bandung has used an online-based collection system and has implemented risk managements well. The internal audit of LAZ has understood and applied the five stages of management phases, namely context formation, risk identification, risk measurement, risk evaluation and risk treatment. Thus, it can be concluded that the role of internal audit in risk management in LAZ Bandung is quite good.