bluuebunny/crossref_metadata_2025 huggingface dataset:
Tratamiento contable de los activos biológicos ganaderos y su incidencia en la toma de decisiones
Authors: Tixi-Torres María Gabriela , Guallpa-Guaman Andrea Elizabeth , Vásconez-Acuña Lenyn Geovanny
Published: November 2020

El objetivo de la investigación consiste en diseñar una metodología de valoración de activos biológicos bajo NIIF para la correcta toma de decisiones en el sector ganadero del cantón Biblián. Fue de tipo descriptiva no experimental. Con la metodología propuesta se identificará el valor razonable después de la aplicación de la NIC 41, el cual determina una gran diferencia con el valor de un activo biológico definido en forma empírica; a través de la aplicación de la norma la inversión realizada es recuperada en menos tiempo que con un valor referente al precio del mercado local. las empresas ganaderas o ganaderos deben realizar un tratamiento contable basados en la NIC 41, ya que les permitirá tomar decisiones acertadas a partir de la disponibilidad de información financiera que refleje el registro de la actividad de transformación de sus activos biológicos.
La constitucionalización del principio de proporcionalidad en España y la actividad legislativa penal
Authors: Villacreses Briones Tania Gabriela , Villacreses Palomeque Jorge Luis
Published: November 2020

La posición del Tribunal Constitucional español frente a la actividad legislativa penal, ha sido desarrollada a través de su jurisprudencia; en esta investigación se ha tomado para análisis al principio de proporcionalidad como límite de creación de la ley penal, según la jurisprudencia constitucional española. Consideramos que dentro de esta sentencia el Tribunal Constitucional además de abordar los problemas que se le plantean, asienta precedente acerca de la amplia libertad que  tiene el Parlamento español a la hora de determinar los delitos y las penas del Código Penal, y el respecto a su labor discrecional, tan distinto al caso ecuatoriano, donde la labor parlamentaria debe adecuarse y desarrollarse en razón de los derechos y principios consagrados en la Constitución y los Tratados Internacionales de Derechos Humanos, con funciones casi absolutamente detalladas y limitadas.
Inclusión laboral de las personas con discapacidad
Authors: Arteaga Ana Jessenia
Published: November 2020

Analizando las constituciones ecuatorianas vemos que el reconocimiento del trabajo como tal hace su primera aparición en la Constitución de 1906, evolucionando progresivamente hasta los tiempos actuales. Lo  relacionado con los derechos de las personas con discapacidad, ve luz a partir de 1998, con la incorporación constitucional del concepto “grupos vulnerables”, que por primera vez reconoce y otorga derechos especiales a este sector de la sociedad. En el año 2006, la legislación laboral infra constitucional fue reformada, dando como resultado la incorporación de algunos mecanismos cuyo ánimo fue el de corregir la limitada o nula inserción socioeconómica de este colectivo que estadísticamente figuraba con uno de los más bajos índices de empleo, debido entre otros factores a la exclusión social de la que eran objeto por sus diferentes o reducidas capacidades, se buscó entonces mediante la reforma normativa el otorgamiento de derechos en pro de la igualdad de oportunidades.
Violencia y discriminación hacia la mujer una mirada desde las reglas de Bangkok
Authors: Pérez Cobo Gyomar , Cuenca Barreto Amanda Isamary
Published: November 2020

La violencia y la discriminación hacia la mujer amerita una particular reflexión a partir de las Reglas de las Naciones Unidas para el tratamiento de las reclusas y medidas no privativas de la libertad para las mujeres delincuentes, conocidas como Reglas de Bangkok, convirtiéndose en el objeto central de esta revisión, con la intención de presentar una visión actual de las acciones que el Ecuador debe emprender para garantizar sus derechos. El documento internacional contiene el compendio de normas que se suman al propósito central de protección de estas personas en estado de vulnerabilidad. La revisión es vital debido a la escasa importancia que se le da en la actualidad, al fenómeno de la mujer victimaria, no así de la mujer víctima, que ha centrado todos los esfuerzos de producción científica y las políticas de Estado, sin advertir como factores determinantes de la delincuencia la violencia y la discriminación.
Seismogravity processes observed in the course of development of the 2011 Tohoku earthquake
Authors: Sobisevich Leonid , Sobisevich Alexey , Kanonidi Konstantin
Published: November 2020

The analysis of the seismogravity processes accompanying the process of development of the tsunamigenic Great East Japan (Tohoku) Earthquake is carried out. Original data and most of the scientific results were obtained at the Geophysical Observatory in Northern Caucasus operated by the Schmidt Institute of Physics of the Earth, Russian Academy of Sciences in collaboration with the Federal Research for Geophysical Service of the Russian Academy of Sciences. Specific attention is focused on the analysis of the structure of the registered seismic processes and the accompanying gravitomagnetic disturbances observed immediately prior to the main seismic event.
Dialogics of idea form-creation as a means of thinking
Authors: Samoylov Oleksandr
Published: November 2020

Theoretical problems mostly arise in a situation of collision of mutually unacceptable provisions of a separate theory, which are in a state of active confrontation. Possible ways or methods of solving these problems are usually indicated by ideas – a kind of psychological tools of thinking, the structure and functional purpose of which allow reflecting the object of comprehension in many ways and holistically, thus preventing the prospect of its extreme manifestations as mutually contradictory concepts of one-sided theoretical ideas-approaches. The peculiarity of the idea form-creation process is determined by the fact that thinking, stimulating the functional purpose of the idea, uses while its development improved rules of concepts derivation and changed principles of proving their truth, which are different from those that caused the theoretical problem occurrence. The improvement of these rules and the change of principles is carried out by taking into account the function of the operational component of thinking as a such, which leaves behind its categorical component only the function of the source of links to be reorganized. Mental operations that carry out this reorganization are triadic inferences, the use of which through thinking as psychological tools is possible by providing the content of the conceivable form of dialogics, i.e. a kind of dialogue logic of two logics, which meets the requirements of dialogical essence of thinking and principles of dialectics. Dialogics considers formally mutually contradictory understanding positions of one and the same object of comprehension, organizing them as a positively significant form of a theoretical problem statement. To solve it successfully, dialogics uses the idea as a mental tool, which is given the form of a dialectical-logical concept that can reflect the essence of a particular theoretical problem, manifested in the form of dialectical unity of formally opposite theoretical positions. Most importantly, the idea as a mental tool of reflecting the essence of the problem raises the theoretical comprehension of the investigated object over the functional degree of finding its place in a particular concept or paradigmatic model and opens the prospect of its objectification at the metaparadigmatic level in an exhaustive category-methodological completeness.
Melancholy either children of Polish Saturn
Authors: Wróbel Szymon
Published: November 2020

The article has a double task, considering the content of Mira Marcinуw’s book, which is important in two controversial topics: madness and its conditions on Poland and its societal psyche, in particular the specifics of Polish melancholy. The author’s views on the status of melancholy in culture and its unique position in public life are presented. The question is: does the melancholic doubt his life? A fairly justified hypothesis would be that the melancholic sees himself as a dead rather than a living body. The significance of the quoted book is that it raises troubling questions but doesn’t give easy answers. First of all, it becomes obvious an unclear – how to develop the epistemological history of melancholy, which is understood as a scientific idea that seeks coherence and adequacy of the medicine language while the political history of melancholy is interpreted as a symptom of this sociocultural context, in this case in relation to Poland. Science in this case creates or selects concepts, although it always systematizes them in a certain place and time. Secondly, it is not clear today how to distinguish the language of melancholy itself, which is the language element of the emergency state, from the language of medicine, which is a means of describing a certain medical disorder. Medicine to a greater extent than we might think refers to normality than to the problematic concept of health. Medicine, while managing human life, adopts a normative attitude, which does not amount to providing advice on how to live wisely, but allows to influence the physical and moral relations of citizens that connect them with society. Thirdly, it is argued that the very concept of melancholy remains dynamic and changeable. The proposed “erotic constellation of melancholy” shows that the subject of melancholy loses the ability to find new objects of love. This incapacity simultaneously leads a person to open nihilism, which is not only the “nothingness of the will” and the usual “will of nothingness”, but also the discovery of the nothingness of knowledge and the futility of the cognition process. The inability to find items worth loving is due to the difficulty of finding items worth the effort to know. Thus, the causes of melancholy go beyond the trivial case of loss and cover all resentments, rejections, failures, disappointments, including despair in the process of cognition. Melancholy brings the subject to ruin, so it is the limit of all medical knowledge, stating that there is no secret of «disorder» in clinical cognition, that there is no secret of madness, and that there is nothing but the study of madness itself. It turns out that madness is recognition of nothingness of the world.
Journalism and fake news in the Covid-19 era. Perspectives for media education in Italy
Authors: Cappello Giovanna , Rizzuto Francesca
Published: November 2020

In this article, drawing from the data collected by the AGCOM during the pandemic crisis, we argue that the emergence of COVID 19 has made more evident the new relationships between the informative cybercascades, the significant need of news during a crisis, the presence of disinformation online, and the relevant consequences on collective narrations, often producing a generalized panic. We also argue that infotainment can be considered a critical turning point in the relationship between true and false in the news because of its fusion of facts, drama, and emotional narrative frames so that it is no longer possible to separate reality from media reconstruction of it. We finally argue that Media Education can help individuals unpack the complexities of this fusion and engage ‘civically’ so that, by combining critical thinking and social action, they can contribute to reconnect (news)media to vital issues such as credibility, freedom of expression, pluralism, democracy, and social change.
STUDI EKPERIMENTAL DAN SIMULASI PENGARUH SUDUT DOUBLE SEGMENTAL BAFFLE DAN LAJU ALIRAN MASSA FLUIDA PADA HEAT EXCHANGER TYPE SHELL AND TUBE TERHADAP PERPINDAHAN PANAS
Authors: Syafi’i Muhammad , Priangkoso Tabah , Darmanto Darmanto
Published: November 2020

Shell and tube heat exchanger (STHX) merupakan jenis penukar kalor yang banyak digunakan di industri. Namun, peningkatan performa penukar kalor ini perlu dilakukan dengan cermat karena alirannya yang kompleks di dalam shell. Shell-and-Tube Heat Exchanger berfungsi untuk menukar energi dalam bentuk panas antara fluida yang berbeda Temperature yang dapat terjadi melalui kontak langsung maupun tidak langsung. Fluida yang bertukar energi dapat berupa energi yang fasenya sama (cair ke cair atau gas ke gas) atau dua fluida yang berbeda fasenya. Penelitian ini mengkaji peningkatan performa dalam bentuk koefisien perpindahan panas total dan efektivitas dengan melakukan variasi sudut baffle menggunakan pendekatan eksperimen. Penukar kalor diuji pada laju aliran massa 0,5; 1; 1,5; dan 2 kg/s dengan variasi sudut baffle 0°, 10°, dan 20°. Pada pengujian eksperimen maupun simulasi semakin kecil sudut baffle maka semakin besar nilai efektivitasnya dan semakin besar laju aliran massa maka semakin besar pula nilai koefisien perpindahan panas totalnya. Pada pengujian simulasi nilai efektivitas dengan sudut baffle 0° memiliki nilai maksimal 1,82% dengan nilai koefisien perpindahan panas total 1607 W/m².K, 10° memiliki nilai 1,79% dengan nilai koefisien perpindahan panas total 1581 W/m².K, dan 20° memiliki nilai 1,70% dengan nilai koefisien perpindahan panas total 1460 W/m².K, nilai efektivitas pada pengujian eksperimen dengan sudut baffle 0° memiliki nilai maksimal 1,38% dengan nilai koefisien perpindahan panas total 741,54 W/m².K, 10° memiliki nilai 1,29% dengan nilai koefisien perpindahan panas total 740,56 W/m².K, dan 20° memiliki nilai 1,14% dengan nilai koefisien perpindahan panas total 739,21 W/m².K.

Kata Kunci: Computational Fluid Dynamics, double segmental baffle, STHX, sudut baffle
ANALISIS LAJU KOROSI PADA METERIAL BAJA ASTM A36 AKIBAT PENGARUH SUDUT BENDING DAN ALIRAN MEDIA KOROSI H2SO4 10%
Authors: Farkhani M.F. , Purwanto H. , Dzulfikar M.
Published: November 2020

Penelitian ini bertujuan untuk mengetahui pengaruh asam sulfat (H2SO4) 10 % terhadap laju korosi pada plat baja karbon rendah mild steel ASTM A36 yang banyak digunakan salah satunya untuk konstruksi pintu air. Dalam penelitian ini plat akan mendapat perlakuan bending dan dicelup menggunakan metode celup diam dan celup putar dengan variasi bending yang digunakan adalah 600, 900, 1200, dan 1800 dengan lama waktu pencelupan 30, 60, dan 90 menit. Ukuran spesimen yang akan diuji dengan panjang 100 mm, lebar 50 mm, dan tebal 3 mm sebanyak 8 spesimen. Hasil dari pengujian menunjukan bahwa laju korosi pada baja ASTM A36 menggunakan metode celup diam laju korosi terbesarnya pada sudut 1800 dengan waktu pencelupan 30 menit yaitu sebesar156,46 mm/tahun. Sedangkan untuk metode celup putar laju korosi terbesarnya terdapat pada sudut 900 dengan waktu 30 menit nilainya sebesar 40,56 mm/tahun. Laju korosi terbesar terhadap ke 2 metode tersebut terdapat pada pencelupan menit 30 ini dikarenakan pada menit 30 kadar keasaman pada larutan H2SO4 masih tinggi dan belum terkontaminasi oleh lingkungan. Aliran media pengkorosi larutan H2SO4 10% dengan menggunakan metode celup putar pengaruhnya kecil terhadap laju korosi dan pada penelitian ini sudut bending pada plat baja ASTM A36 tidak terlalu berpengaruh besar terhadap laju korosi ini dikarenakan gaya tekan yang diterima spesimen kecil.

Kata kunci: Baja karbon rendah ASTM A36, korosi, bending, asam sulfat H2SO4, variasi metode celup
DESAIN TURBIN ANGIN POROS VERTIKAL UNTUK PENGGERAK POMPA AIR
Authors: Riyadi Slamet , Margen Sendie Yuliarto
Published: November 2020

Potensi energi angin di indonesia sangat melimpah. Sumber energi dari angin merupakan salah satu sumber energi bersih. Pengembangan turbin angin sangat sesuai dengan kondisi tersebut. Penelitian ini menggunakan metode eksperimental dengan menggunakan turbin angin vertical dengan jari-jari 70 cm, tinggi 150 cm, dengan dua buah sudu lebar 40 cm. Untuk mempermudah dalam pengambilan data antara sudu dan lengan turbin di buat seperti sendi agar mudah untuk mengatur sudut sudu. Hasil data yang didapatkan dari penelitian ini adalah daya terbesar turbin angin poros vertikal yaitu 9,2 watt yang menghasilkan debit air sekitar 0,086 m3/s, dengan daya teoretis 0,0002334 watt. Karakter dari turbin angin poros vertikal ini dapat berputar jika di kenai kecepatan angin yang rata-rata 3 m/s, sehingga turbin angin poros vertikal ini membutuhkan tempat yang lapang atau tinggi untuk mendapatkan hasil yang lebih maksimal sehingga sudu dapat berputar dengan baik pula. Dalam pengambilan data mencari debit air yang maksimum dari pengujian kecepatan angin 1 s/d 4 m/s diperoleh debit air yng paling tinggi.

Kata Kunci : debit air, pompa hidran, turbin angin.
KARAKTERISASI KOMPOSIT MATRIK RESIN EPOXY BERPENGUAT SERAT GLASS DAN SERAT PELEPAH SALAK DENGAN PERLAKUAN NaOH 5%
Authors: Yuliyono Timbul , Purwanto H. , Respati S.M. Bondan
Published: November 2020

Serat pelepah tanaman salak sebagai bahan komposit merupakan salah satu alternatif dalam pembuatan komposit secara ilmiah. Tujuan dari penelitian ini untuk mengetahui perbandingan kekuatan tarik dan mengetahui sifat fisik dari komposit serat glass dan serat pelepah salak dengan matrik resin epoxy dengan variasi fraksi volume serat. Sifat-sifat mekanik yang diperoleh yaitu kekuatan tarik, regangan, dan modulus elastisitas. Untuk mengetahui sifat fisik dari komposit melalui pengamatan foto makro dari penampang patahan spesimen uji tarik. Pembuatan benda uji komposit dengan proses hand lay-up menggunakan standar ukuran ASTM D 638M-84. Komposit dibuat dengan fraksi volume (94% resin dan 6% serat glass), (94% resin dan 6% serat pelepah salak), (94% resin, 3% serat glass dan 3% serat pelepah salak), ( 94% resin, 4% serat glass dan 2% serat pelepah salak), (94% resin, 2% serat glass dan 4% serat pelepah salak) dan matrik tanpa serat. Berdasarkan hasil penelitian yang telah dilakukan, dapat disimpulkan bahwa nilai kekuatan tarik maksimum diperoleh pada komposit fraksi volume 94% resin dan 6% serat glass sebesar 35,49 Mpa. Kekuatan tarik komposit terendah pada fraksi volume 94% resin dan 6% serat pelepah salak sebesar 14,90 Mpa. Nilai regangan tertinggi didapat pada komposit fraksi tanpa serat yaitu 34,66%. Penambahan serat berpengaruh pada modulus elastisitas komposit. Pada komposit fraksi volume 94% resin dan 6% serat glass memperoleh nilai modulus elastisitas paling tinggi yaitu 434,19 Mpa. Hasil foto makro yang terlihat pada spesimen adalah fiber break, fiber pull out, void dan matrik cracking.

Kata kunci:epoxy, glass, komposit, pelepah salak, sifat mekanik, sifat fisik.
HISTOTOPOGRAPHY OF THE OVIDUCTS IN FETUS
Authors: Kuzniak Nataliia , Protsak Tetiana , Marchuk Оleg , Fedoniuk Larysa , Kamyshnyi Alex , Penteleichuk Nataliia , Stoliar Denys , Dmytrenko Roman
Published: November 2020

Іntroduction: Nowadays, during formation and development of medicine, the main sector of health care is the protection of maternity and childhood. According to the Ministry of Health of Ukraine, inflammatory diseases of the reproductive system make up 60-65% of all gynecological diseases, among them inflammation of the fallopian tubes and ovaries is 79,6%, which occurs predominantly at young age.
The aim is to study the microscopic structure of the oviducts wall in different anatomical parts during the embryonic period of human ontogenesis.
Materials and methods: Were studied uterine tubes of the 4-10 months’ embryos. We used a light microscopy method and morphometry to describe the peculiarities of
oviducts’ infundibulum, isthmus and ampullary part in fetus from 81 mm to 375 mm PCL.
Results: The histotopography of the oviducts tunics and its parts (infundibulum, ampullary part, isthmus and uterine part) in the fetal period of ontogenesis is described in the article. The thickness of the oviduct wall in the dynamics of the fetal period increases in the direction from the infundibulum to the uterine part of the tube. The main part of the thickness of the oviduct wall is presented by muscles. The thickness of the circumferential muscle layer predominates over the thickness of the longitudinal in 2.5-2.8 times. Mucosa is thicker the isthmus, thinnest in the ampullary part of the uterine tube.
Conclusions: The thickness of the infants oviduct wall in the dynamics increases in the direction from its infundibulum to the uterine part. The main part of the thickness of the oviduct wall is the tunica muscularis. The thickness of the circular muscle layer predominates the thickness of the longitudinal 2.5-2.8 times. Mucosa is thicker in the isthmus, the thinnest in the ampullary part. It is expedient to study the histotopography of the oviduct in the neonatal period of human ontogenesis.
ASSOCIATIONS OF IRS-1 POLYMORPHISM WITH VARIOUS COMPONENTS OF THE METABOLIC SYNDROME IN HYPERTENSIVE PATIENTS
Authors: Kochuieva Maryna , Psarova Valentyna , Ruban Larysa , Kyrychenko Nataliia , Alypova Olena , Matlai Olha , Shalimova Anna
Published: November 2020

Introduction: The metabolic syndrome is one of the most discussed cross-disciplinary problems of modern medicine. Now there are various definitions and criteria of diagnostics of metabolic syndrome. The abdominal obesity is considered the main component of the metabolic syndrome, as a reflection of visceral obesity which degree is offered to be estimated on an indirect indicator – a waist circumference. Alongside with abdominal obesity, a number of classifications distinguish insulin resistance (IR) as a diagnostic criterion of metabolic syndrome. It is proved that IR is one of the pathophysiological mechanisms influencing the development and the course of arterial hypertension (AH), type 2 DM and obesity. There are two components in the development of IR: genetic (hereditary) and acquired. In spite of the fact that IR has the accurate genetic predisposition, exact genetic disorders of its appearance have not been identified yet, thus demonstrating its polygenic nature.
The aim: To establish possible associations of the insulin receptor substrate-1 (IRS-1) gene polymorphism with the severity of the metabolic syndrome components in patients with arterial hypertension (AH).
Materials and methods: 187 patients with AH aged 45-55 years and 30 healthy individuals. Methods: anthropometry, reactive hyperemia, color Doppler mapping, biochemical blood analysis, HOMA-insulin resistance (IR), glucose tolerance test, enzyme immunoassay, molecular genetic method.
Results: Among hypertensive patients, 103 had abdominal obesity, 43 - type 2 diabetes, 131 - increased blood triglycerides, 19 - decreased high density lipoproteins, 59 -prediabetes (33 - fasting hyperglycemia and 26 - impaired glucose tolerance), 126 had IR. At the same time, hypertensive patients had the following distribution of IRS-1 genotypes: Gly/Gly - 47.9%, Gly/Arg - 42.2% and Arg/Arg - 10.7%, whereas in healthy individuals the distribution of genotypes was significantly different: Gly/Gly - 86.8% (p<0.01), Gly/ Arg - 9.9% (p<0.01) and Arg/Arg - 3.3% (p<0.05). Hypertensive patients with Arg/Arg and Gly/Arg genotypes had significantly higher HOMA-IR (p<0.01), glucose, insulin and triglycerides levels (p<0.05), than in Gly/Gly genotype. At the same time, body mass index, waist circumference, blood pressure, adiponectin, HDL, interleukin-6, C-reactive protein, degree of endothelium-dependent vasodilation, as well as the frequency of occurrence of impaired glucose tolerance did not significantly differ in IRS-1 genotypes.
Conclusions: in hypertensive patients, the genetic polymorphism of IRS-1 gene is associated with such components of the metabolic syndrome as hypertriglyceridemia and fasting hyperglycemia; it is not associated with proinflammatory state, endothelial dysfunction, dysglycemia, an increase in waist circumference and decrease in HDL.
SAFE NATURAL ENVIRONMENT AS GUARANTEE OF EXERCISING
THE RIGHT TO HEALTH
Authors: Bobkova Antonina H. , Trotska Maryna V.
Published: November 2020

Introduction: The right to health is one of the most important human rights and its proper exercising allows for the exercise of other rights. One of the guarantees of this right is the safe natural environment, which, on the one hand, allows to maintain the health at the proper level without worsening it, and, on the other hand, to improve and prevent negative consequences concerning it. The proper state of the natural environment is reflected through the relevant qualitative characteristics of each of the natural resources that are included in it, and in aggregate, reflected in the corresponding natural interactions between them.
The aim: The study is aimed at inquiring into the right to health and importance of the safe natural environment in order to provide it.
Materials and methods: Statutory regulation and scientific positions of scholars in the field of the above-mentioned issue are studied in this article. The study analyzes
generalized information from scientific journals by means of scientific methods from a medical and legal point of view. This article is based on dialectical, comparative, analytic, synthetic and comprehensive research methods. Within the framework of the systematic approach, as well as analysis and synthesis, the concept of the right to health and its place in the provision of the safe natural environment is researched.
Review: The right to health is regarded as a person’s awareness of the existence of appropriate ways, means and conditions that enable them to take care of their physical and psychological state by carrying out appropriate actions or refraining from doing so, thereby preventing or eliminating negative consequences that may threaten or do threaten their proper state of health. Along with others, the safe natural environment is a prerequisite that allows their full enjoyment of the right to health.
Conclusions: The guarantee of the right to health must be based on an integrated approach in understanding the nature of the factors, their interconnection and impact on each other in providing it. The safe natural environment is a prime element when implementing the outlined opportunity. Failure to comply with its proper condition, both directly and indirectly, affects its other components while implementing it. The level of its safety is determined by the proper qualitative state of natural resources, their interconnection and impact on human health. Ensuring the safety of the natural environment, both directly and indirectly, means creating requisite conditions for exercising the right to health.
INTEGRATIVE MEDICINE THROUGH ISLAMIC PERSPECTIVE IN RESPECTING PANDEMIC COVID-19
Authors: Elvina Meity
Published: November 2020

ABSTRACT

 

One of the problems in the world today is the outbreak of the coronavirus pandemic case. The case of this pandemic outbreak also cannot be separated from the problems known to Muslims. Overall, Al-Quran and al-Hadith explain about many stories that we might be able to take the event of ibrah. Islam's perfection has provided many solutions to various kinds of problems that arise by a Muslim, including the coronavirus pandemic, which is of considerable concern to humans worldwide.

Muslim needs to have his own perspective in responding to this coronavirus outbreak's pandemic incident. So that we can do our best to overcome the pandemic case of the coronavirus outbreak by "making peace" with microorganisms, which are also God's creatures, we can contemplate answering questions related to this, for example, why is this outbreak the case of the current pandemic? The perfect guide to life, namely the book of Allah Al Quran, already has the answer.
Scenario Analysis Approach
for Operational Risk in Insurance Companies
Authors: Vyskočil Michal
Published: November 2020

The article deals with the possibility of calculating the required capital in insurance
companies allocated to operational risk under Solvency II regulation and the aim of this
article is to come up with model that can be use in insurance companies for calculating
operational risk required capital. In the article were discussed and compared the frequency
and severity distributions where was chosen Poisson for frequency and Lognormal for
severity. For the calculation, was used only the real scenario and data from small CEE
insurance company to see the eﬀect of the three main parameters (typical impact, Worst case
impact and frequency) needed for building the model for calculation 99,5% VaR by using
Monte Carlo simulation. Article comes up with parameter sensitivity and/or ratio sensitivity
on calculating capital. From the database arose two conclusions related to sensitivity where
the first is that the impact of frequency is much higher in the interval (0;1) than above the
interval to calculated capital and second conclusion is Worst case and Typical Case ratio,
where we saw that if the ratio is around 150 or higher the calculated capital is increasing
faster that the ration increase demonstrated on the scenario calculation.
A Pattern-Hierarchy Classifier for Reduced Teaching
Authors: Greer Kieran
Published: November 2020

This paper describes a design that can be used for Explainable AI. The lower level is a nested ensemble of patterns created by self-organisation. The upper level is a hierarchical tree, where nodes are linked through individual concepts, so there is a transition from mixed ensemble masses to specific categories. Lower-level pattern ensembles are learned in an unsupervised manner and then split into branches when it is clear that the category has changed. Links between the two levels define that the concepts are learned and missing links define that they are guessed only. This paper proposes some new clustering algorithms for producing the pattern ensembles, that are themselves an ensemble which converges through aggregations. Multiple solutions are also combined, to make the final result more robust. One measure of success is how coherent these ensembles are, which means that every data row in the cluster belongs to the same category. The total number of clusters is also important and the teaching phase can correct the ensemble estimates with respect to both of these. A teaching phase would then help the classifier to learn the true category for each input row. During this phase, any classifier can learn or infer correct classifications from some other classifier's knowledge, thereby reducing the required number of presentations. As the information is added, cross-referencing between the two structures allows it to be used more widely, where a unique structure can build up that would not be possible by either method separately.
Lėtinės inkstų ligos (LIL) rizikos veiksnių paplitimas, kontrolė tarp pirminės sveikatos priežiūros centro pacientų
Authors: Narščiūtė Indrė , Merliūnienė Justė , Foktaitė-Kuktienė Irma , Minelgienė Rūta
Published: November 2020

Tyrimo tikslas. Įvertinti LIL rizikos veiksnių dažnį bei kontrolę tarp Lietuvos sveikatos mokslų universiteto ligoninės Kauno klinikų Šeimosmedicinos klinikos pirminės sveikatos priežiūros centro pacientų. Tyrimo metodika. Atliktas retrospektyvusis tyrimas. Statistinei duomenų analizei naudotas „SPSS 20.0“ programinis paketas. Reikšmingumo lygmuo pasirinktas p<0,05. Rezultatai. Bent vienas LIL rizikos veiksnys nustatytas 321 pacientui.Dažniausiai nustatytas LIL rizikos veiksnys buvo III°AH (18,8 proc.). 93,8 proc. tiriamųjų, kuriems nustatyti LIL rizikos veiksniai, bent kartą per dvejus metus buvo atlikti kreatinino ir GFG tyrimai. BŠT (41,4 proc.), albuminurijos bei albumino ir kreatinino santykio šlapime (13,1 proc.) tyrimai atliekami ypač retai. Gydymas NVNU taikytas 8,1 proc. pacientų, turinčių LIL rizikos veiksnių, tačiau nė vienam pacientui, kurio GFG mažesnis nei 30 ml/min./1,73 m2. 14 pacientų (53,8 proc.) skiriant NVNU dozę, nebuvo atsižvelgta GFG. Išvados. III° AH buvo dažniausiai pasitaikantis LIL rizikos veiksnys. Kreatinino ir GFG tyrimai atlikti didžiajai daliai pacientų, turinčių LIL rizikos veiksnių, BŠT bei albumino ir kreatinino santykio tyrimai atlikti žymiai rečiau. Nedidelė dalis pacientų, kurių gydymui skirta NVNU, vartojo šiuos vaistus nesumažintomis dozėmis, tačiau nė vienam pacientui neskirta NVNU, kai jie kontraindikuotini.
IDENTIFICATION OF THE POTENTIAL RNA EDITING SITES FOR GENES OF INTRINSICALLY DISORDERED PROTEINS ASSOCIATED WITH NEURODEGENERATIVE DISEASES
Authors: Medvedeva M. , Muronetz V.
Published: November 2020

A search for genes of naturally unfolded proteins associated with neurodegeneration containing tyrosine codons with the potential for editing RNA by adenosine deaminases was performed, and such sites were tested for the alpha - synuclein gene in the SH-SY5Y cell line.
DETECTION OF BIOLOGICAL AGENTS USING ELECTROMECHANICAL BIOSENSORS
Authors: Yaminsky I.
Published: November 2020

Electromechanical biosensors allow detecting viruses with high sensitivity – up to single viral particles. In this work, electromechanical systems based on cantilever biochips are used to detect biological agents.
THE CRISPR/CAS9 SYSTEM TARGETING GENES OF HSV-1 REPLICATIVE COMPLEX SUPPRESSES THE INFECTIOUS ACTIVITY OF THE VIRUS IN MAMMAL CELLS
Authors: Demidova N. , Karpov D. , Kushch A.
Published: November 2020

The ability of CRISPR/Cas9 plasmids encoding various HSV-1 genes to inhibit HSV-1 infection in vitro was studied. It was shown that CRISPR/Cas9 plasmids encoding two gRNA targeted against UL52 and UL29 genes of the HSV1 primase-helicase complex suppressed the viral reproduction in a Vero cell culture completely.
NEW POSSIBILITIES OF STRUCTURAL MORPHOLOGICAL PECULIARITIES INVESTIGATION BY QUANTITATIVE PHASE IMAGING METHOD
Authors: Zolotova M. , Ivashchenko M. , Ignatiev P. , Metelin V. , Talamanova M.
Published: November 2020

The possibility of quantitative phase imaging method for the assessment of structural morphological erythrocytes peculiarities under normal and stress conditions were studied. It is stated that quantitative phase imaging is an important instrument which allows to visualize red blood cells. New aspects of stress influence on functional cells morphology are defined.
CONTROL OF PHYSICO-CHEMICAL PROPERTIES OF A LIPID NANOCONTAINER FOR DELIVERY OF DRUGS WITH LOW BIOAVAILABILITY
Authors: Yakimov I. , Le-Deygen I. , Skuredina A. , Kudryashova E.
Published: November 2020

We have used two ways to control the physicochemical properties of liposomal nanocontainers for the delivery of fluoroquinolones: variation of the lipid composition of liposomes and selection of a functionalizing polymer based on chitosan mannose derivatives. The presence of anionic phospholipid cardiolipin in the liposome composition increases the loading efficiency by 5-20%. The mechanism of drug incorporation into membranes was studied, and the main binding sites were determined. The functionalization of the liposomal surface was carried out by chitosan mannose derivatives of various molecular weights, potentially providing targeted delivery to alveolar macrophages.
STUDYING THE LOCAL MECHANICAL PROPERTIES OF LIVING CELLS VIA SCANNING ION-CONDUCTING MICROSCOPY
Authors: Vaneev A. , Savin N. , Yakovlev A. , Alova A. , Lavrushkina S. , Erofeev A. , Gorelkin P. , Kireev I. , Majouga A. , Korchev Y. , Novak P. , Klyachko N.
Published: November 2020

The mechanical properties of PC-3 tumor cells of human prostate cancer before and after exposure to substances acting on the actin cytoskeleton, microtubules, and cell nucleus were measured by scanning ion-conducting microscopy. Changes in local mechanical properties corresponding to the mechanisms of action of these substances were found
ALBUMIN-COATED MAGNETIC NANOPARTICLES AS A UNIVERSAL NANOVEHICLE FOR TARGETED DELIVERY OF DIAGNOSTICAND THERAPEUTIC AGENTS TO MALIGNANT TISSUES
Authors: Skorikov A. , Ivanova A. , Abakumov M. , Chekhonin V.
Published: November 2020

Albumin-coated iron oxide magnetic nanoparticles were designed and synthesized. It can act as contrast agents for MRI diagnostics of various tumors, as well as a nanovehicle for targeted delivery of chemotherapy and immunotherapy drugs.
MULTISENSORY LEARNING SYSTEM FOR NON-INVASIVE DETERMINATION OF THE FUNCTIONAL STATE OF THE BODY IN EXTREME CONDITIONS
Authors: Zaitseva A. , Kislyakov Y. , Avduschenko S.
Published: November 2020

The project is implementing a new principle of non-invasive diagnostics and biomedical research using an artificial, multi-sensory, trained analytical system to monitor the professional fitness of military personnel in terms of exhaled air condensate, in which significant metabolic products are present. The results of the studies show that the subjects are divided into groups of different adaptability and sensitivity to extreme conditions. The proposed method based on the multi-sensory trained diagnostic system allows non-invasive instrumental control and selection of spe- cialists for their functioning in extreme conditions of high mountains.
THE CONSTRUCTION OF TUMOR-SELECTIVE ADENOVIRAL VECTORS WITH MODIFIED TROPISM AND INCREASED ONCOLYTIC ACTIVITIES USING ADVANCED GENETIC ENGINEERING
Authors: Sosnovtseva A. , Chekhonin V.
Published: November 2020

A panel of replication competent adenoviral vectors based on the adenovirus 5 genome with high tumor selectivity, modified tropism and increased oncolytic activities to overcome the intratumoral heterogeneity and chemotherapeutic resistance are de novo constructed and characterized in vitro.
WATER-SOLUBLE PERRORAL DELIVERY SYSTEM OF ESSENTIAL LIPIDS BASED ON THEIR COMPLEX WITH BIOPOLYMERS
Authors: Zelikina D. , Komarova А. , Balakina Е. , Palmina N. , Bogdanova N. , Аntipova А. , Martirosova Е. , Semenova М.
Published: November 2020

A water-soluble and nanoscale peroral system has been obtained for the delivery of essential lipids. It was based on the supramolecular complexes of the lipids with biopolymers. This system provides both the high protectionof lipids against oxidation during storage and the ease addition of their adequate amounts into various liquid prophylactic agents.
ABILITY OF THE NEW IMMUNOSTIMULATOR SAPOMAX TO STIMULATE A SPECIFIC IMMUNE RESPONSE TO GENE-ENGINEERED PROTEINS OF HEPATITIS
Authors: Turmagambetova А. , Alexyuk M. , Alexyuk P. , Sokolova N. , Zaitseva I. , Berezin V.
Published: November 2020

It was shown that adjuvant Sapomax effectively stimulates the formation of levels of various classes of immunoglobulins against gene-engineered proteins of the viruses of hepatitis B and C. Moreover, the absence of stimulation of IgG3 levels indicates the absence of allergic manifestations of the developed immunostimulator.
STIMULATION OF SOME GENES OF GENERAL ANTI-VIRAL IMMUNITY BY COMPLEX PLANT PREPARATION
Authors: Bogoyavlenskiy А. , Alexyuk М. , Omirtaeva E. , Akanova K. , Berezin V.
Published: November 2020

It was shown that the activation of genes that play a decisive role in the recognition of RNA of viruses that enter the cell through receptor-mediated endocytosis or phagocytosis can be significantly increased by introducing of nonspecific immunostimulants of plant origin containing triterpene with glycosylated methoxyflavonoid.
ANTIGLYCATION ACTIVITY MODELING BY THE METHODS OF MACHINE LEARNING
Authors: Vasiliev P.
Published: November 2020

A multilevel consensus model of the antiglycation activity has been built by the machine learning methods using IT Microcosm.
GENE LOSS PREDICTION BASED ON GENOMIC STRUCTURE
Authors: Rubanov L. , Shilovsky G. , Seliverstov A. , Zverkov O.
Published: November 2020

We have developed an efficient algorithm implemented in a program for a multiprocessor computing system, which makes it possible to discover genes lost or acquired during the evolution of most species from a given set. The new approach takes into account the mutual arrangement of genes on a chromosome and allows us to simultaneously consider hundreds of species.
The research was carried out using supercomputers at the Joint Supercomputer Center of the Russian Academy of Sciences (JSCC RAS).
MICROBIAL DIVERSITY IN HEAVY OIL RESERVOIRS AS A BASIS FOR DEVELOPMENT OF BIOTECHNOLOGIES FOR ENHANCED OIL RECOVERY
Authors: Babich T. , Semenova E. , Grouzdev D. , Bidzhieva S. , Ershov A. , Serdukov D. , Volkov D. , Bugaev K. , Khisametdinov M. , Borzenkov I. , Nazina T.
Published: November 2020

A microbiological method was proposed for enhanced oil recovery from heavy oil reservoirs, which is based on injection of hydrocarbon-oxidizing bacteria, an oxidant (H2O2 solution), and ammonium and phosphorus salts. Industrial trials at the experimental site of the Cheremukhovskoe oilfield resulted in additional recovery of heavy oil (over 1140 t).
COW MILK MICROBIAL CONTENT INFLUENCE ON NEUTROPHILS AND CD4+ MILK CELLS
Authors: Atanasova M. , Ivanov Y. , Godjevargova T.
Published: November 2020

The purpose of this research was to determine the total cell count and some pathogenic microorganisms in 105 milk samples. The somatic cell count (SCC) was significantly higher in mastitic milk samples compared to the uninfected glands and dirty milk samples. The total number of microorganisms (TBC) in dirty and mastitic milk was 5-20 times more than results in healthy milk samples. The influence of the selected pathogenic microorganisms on the number of somatic cells, neutrophils and CD4+ cells was studied. The obtained results were compared with those by a flow cytometer Guava easyCyteTM 8HT. The proportion of different cell types (neutrophils and CD4+ cells) has been shown to be influenced by the type of pathogens.
MICROBIAL NUTRIPARAPHARMACEUTICALS IN AN INTEGRATED VEGETABLE EDIBLE RAW MATERIAL
Authors: Zuev R. , Moliere A.
Published: November 2020

The technology for obtaining nutriparafamaceuticals by solid-phase cultivation of microbial associations from yeast and bacteria isolated from edible plant and animal products on plant food raw materials has been developed.
PIGMENT COMPOSITION OF THE GREEN ALGA HAEMATOCOCCUS PLUVIALIS DURING ACTION OF MULTIPLE ASTAXANTHIN ACCUMULATION INDUCTORS
Authors: Goncharik R. , Kulikov E. , Selishcheva A.
Published: November 2020

The content of astaxanthin, including its mono- and diesters, and photosynthetic pigments, was studied in cells of H. pluvialis strain IBCE-H17 under combined prolonged action of several inducers of astaxanthin accumulation. The ineffectiveness of the simultaneous introduction of several inducers of astaxanthin accumulation in the culture medium during high-intensity light treatment was shown.
DEVELOPMENT OF OSTEOPLASTIC MATERIAL IMPREGNATED WITH PLASMID ENCODING BONE MORPHOGENETIC PROTEIN-2
Authors: Bukharova T. , Vasilyev A. , Kulakov A. , Goldstein D.
Published: November 2020

A new gene-activated osteoplastic based on chitosan material impregnated with plasmid with the BMP-2 gene has been developed. The material had an osteoinductive effect on mesenchymal stromal cells (MSC).
AERATION EFFECT ON BACTERIAL NANOCELLULOSE DEGREE OF POLYMERIZATION
Authors: Shavyrkina N. , Budaeva V.
Published: November 2020

The forced aeration at flow rates of 3.3, 6.3, 9.2,12.3 and 16.7 L/min was found to have an ambiguous effect on the degree of polymerization of bacterial nanocellulose.
ELECTROSPINING OF COLLAGEN MATRIXES: STRUCTURAL STABILIZATION AND MECHANICAL PROPERTIES
Authors: Mariyanats A. , Popov V.
Published: November 2020

The mechanical properties of highly porous collagen matrices made by electrospinning and stabilized with 1,4-butanediol diglycidyl ether (BDDGE) were studied depending on the concentration of BDDGE in the initial composition, the type of solvent and the concentration of BDDGE in the solution for structural stabilization, and the matrices holding time in this solution
YIN-YANG GENES IN CANCER, SCHIZOPHRENIA AND AUTISM SPECTRUM DISORDERS
Authors: Malsagova K. , Stepanov A. , Sinitsyna A. , Izotov A. , Kaysheva A.
Published: November 2020

Literature review focuses on the genes associated with the development of diseases with inverse comorbidity, including schizophrenia, autism spectrum disorders, and most common cancers was carried out. The present study summarizes the information on 10 yin-yang genes that can be associated with both mental disorders and cancer.
A RELAÇÃO DEMOCRÁTICA: PRINCÍPIO PARA PRÁTICA DA EDUCAÇÃO INCLUSIVA
Authors: De Lima Simões dos Santos Ilma , De Almeida Alexandre Márcio
Published: November 2020

O objetivo deste artigo é compreender a educação inclusiva e a concepção de Freire, Rancière e Jacotot na construção das práticas  emocráticas, que nos propõe, uma filosofia de educação capaz de nos orientar a uma crítica do princípio igualitário, tendo como  bjetivo compreender a construção das práticas democráticas na educação inclusiva, enquanto o pensamento de Rancière é uma  oncepção sobre o ato de educar, a compreensão do conceito de inteligência e para Rancière se apoia na experiência pedagógica de  oseph Jacotot. É em sua facilidade histórica e empírica que ele encontra elementos para desenvolver uma reflexão sobre a educação  ue ao fundamentar-se no princípio igualitário pode propor tanto uma nova pedagogia de ensino, como também uma ideia  ormativa  enovada para a compreensão do que entender por uma educação inclusiva bem-sucedida.
Phase II of the LAMOST-Kepler/K2 Survey. I. Time Series of Medium-resolution Spectroscopic Observations
Authors: Zong Weikai , Fu Jian-Ning , Cat Peter De , Wang Jiaxin , Shi Jianrong , Luo Ali , Zhang Haotong , Frasca A. , Molenda-Żakowicz J. , Gray R. O. , Corbally C. J. , Catanzaro G. , Cang Tianqi , Wang Jiangtao , Chen Jianjun , Hou Yonghui , Liu Jiaming , Niu Hubiao , Pan Yang , Tian Hao , Yan Hongliang , Zhang Yong , Zuo Heng
Published: November 2020

Phase II of the Large Sky Area Multi-Object Fibre Spectroscopic Telescope (LAMOST)-Kepler/K2 survey (LK–MRS), initiated in 2018, aims at collecting medium-resolution spectra (R ∼ 7500; hereafter MRS) for more than 50,000 stars with multiple visits (∼60 epochs) over a period of 5 yr (2018 September to 2023 June). We selected 20 footprints distributed across the Kepler field and six K2 campaigns, with each plate containing a number of stars ranging from ∼2000 to ∼3000. During the first year of observations, the LK–MRS has already visited 13 plates 223 times over 40 individual nights, and collected ∼280,000 and ∼369,000 high-quality spectra in the blue and red wavelength ranges, respectively. The atmospheric parameters and radial velocities for ∼259,000 spectra of 21,053 targets were successfully calculated by the LAMOST stellar parameter pipeline. The internal uncertainties for the effective temperature, surface gravity, metallicity, and radial velocity are found to be 100 K, 0.15 dex, 0.09 dex, and 1.00 km s−1, respectively, when derived from a medium-resolution LAMOST spectrum with a signal-to-noise ratio (S/N) in the g band of 10. All of the uncertainties decrease as S/N increases, but they stabilize for S/N > 100. We found 14,997, 20,091, and 1514 stars in common with the targets from the LAMOST low-resolution survey (LRS), Gaia, and the Apache Point Observatory Galactic Evolution Experiment (APOGEE), respectively, corresponding to fractions of ∼70%, ∼95%, and ∼7.2%. In general, the parameters derived from LK–MRS spectra are consistent with those obtained from the LRS and APOGEE spectra, but the scatter increases as the surface gravity decreases when comparing with the measurements from APOGEE. A large discrepancy is found with the Gaia values of the effective temperature. Comparisons of the radial velocities of LK–MRS to Gaia and LK–MRS to APOGEE nearly follow a Gaussian distribution with means of μ ∼ 1.10 and 0.73 km s−1, respectively. We expect that the results from the LK–MRS spectra will shed new light on binary stars, asteroseismology, stellar activity, and other research fields.