bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of the formulation on the thermophysical properties and the quality parameters of dairy ice cream
Authors: Zambrano-Mayorga Luis Felipe , Ramírez-Navas Juan Sebastian , Ochoa-Martínez Claudia Isabel
Published: April 2019

Thermophysical properties and the quality parameters of vanilla dairy ice cream were evaluated as a function of formulation. The sucrose were substituted for alternative sweeteners, and whey powder was used to adjust the nonfat solid content. A mixture design for four ingredients (sucrose, fructose, stevia, and whey powder) was applied. The ice cream composition was correlated with the thermophysical properties (density, viscosity, heat capacity, thermal diffusivity, and thermal conductivity). The optimal formulation, based on the quality parameters (time until first drop falls, melting time, and overrun), was determined. Additionally, the quality parameters were correlated with the thermal properties. The whey powder had a positive effect on the variables measured, improving the quality parameters. The best formulation was 12.1782 % whey powder and 0.0218 % stevia. No significant sensory instead difference was found between this formulation and a commercial ice cream sample. Sucrose was totally replaced with stevia and whey powder in the final product.
Optimizing acceptability of mango jam enriched with pectin from cacao husk (Theobroma cacao L.)
Authors: Torregroza Espinosa Angelica Maria , Gomezcaceres Pérez Luty Del carmen , Rodríguez Manrique Jhonatan Andres , López Martínez Rolando José
Published: April 2019

This experiment was conducted in order to optimize and quantify the acceptability of mango jam enriched with pectin extracted from husk of cacao grown in the department of Sucre, Colombia. The experiment was performed using a two-factor, completely randomized design: pectin concentration (0.2%, 0.4%, 0.6%) and citric acid concentration (0.1%, 0.3%, 0.5%). All experiments were conducted in triplicate for each treatment, for a total of 27 experimental units. Variables such as fresh fruits (65.5%) and sugar (34.0%) were held constant. Data analysis was performed using an analysis of variance while the comparison of means was performed by the Tukey's range test. After 24 hours, a test for measuring product acceptability was conducted among 60 people using a 7-point hedonic scale. The survey yielded an acceptability value (I like moderately) of 6.7 for pectin concentrations of 0.2% and citric acid concentrations of 0.3%.
Towards the reduction of the effects of muscle fatigue on myoelectric control of upper limb prostheses
Authors: Díaz-Amador Roberto , Mendoza-Reyes Miguel A.
Published: April 2019

This paper presents an investigation focused on the impact of muscle fatigue on a pattern recognition scheme for myoelectric control that uses three features sets and a Linear Discriminant Analysis classifier. Separability and repeatability between classes were used to evaluate the features changes while muscle fatigue was induced. Results show that while muscle fatigue is increasing over time, both separability and repeatability of the classes decrease. Finally two training schemes that use data acquired under fatigue, multiconditional training and selective classification, were evaluated using the Total Error Rate (TER). Results indicate that, when LDA classifier was trained whit no-fatigue, moderated fatigue and fatigue data, TER decreased to moderated and fatigue data, but increased to no-fatigue data. On the other hand, using three LDA classifiers to each of the condition, TER decreased to 9.26 % and 11 % in moderated fatigue and fatigue cases, while no-fatigue case was not affected.
Experimental studies on the mechanical behavior of Mayan archeological rocks
Authors: Rios Soberanis Carlos Rolando , Ley Paredes Victor Jose , Perez Pacheco Emilio , Vinajera Reyna Carlos Emilio , Wakayama Shuichi , Sakai Takenobu
Published: April 2019

Mayan buildings have been the subject of significant archaeological and architectural research; however, so far there have been no relevant references concerning structural or mechanical behavior. Ancient Mayan constructors used calcareous rocks to build temples and housing that were placed systematically to withstand mechanical loads in the structures. This paper studies the mineralogical and mechanical characteristics of calcareous stony material that formed part of Mayan archeological vestiges in Yucatan area. The orientation of the rocks´ geological strata was taken into account to study mechanical behavior from cylindrical cores in compressing test. On the other hand, bars were also manufactured to simulate lintel or architrave structural performance. Compression and bending tests confirmed a high influence of the geological layer orientation, since the mechanical properties of such rocks were found to vary with direction. Acoustic emission was used to provide information referring to onset and propagation of damage in cylinder and bar samples.
Evaluation of toxicity from leachate lagoons sediments, using the toxicity leaching procedure - TCLP and acute toxicity tests
Authors: Torres Lozada Patricia , Carabalí Rivera Yazmin , Barba Ho Luz Edith
Published: April 2019

Landfills have been the most used alternative for final municipal solid wastes disposal, however, this system is the responsible of contamination problems associated with the generation of leachates, sediments and toxic gasses emissions. The sediments occur by the organic and inorganic matter precipitation from leachates dumped in retention lagoons, which can present toxic characteristics than affect the environment. The aim of this work was to evaluate the potential toxicity of leachates from a municipal landfill, using the TCLP procedure and acute toxicity assays with Daphnia pulex and Poecilia reticulata as biological indicators. The results showed that the sediment evaluated, did not exceed the stablished levels suggested by the EPA for the TCLP test, nor were they toxic to the organisms used. This results, suggests a potential agricultural use of this material in acid soils, since the nature of leachate sediments are pH alkaline and rich in nutrients and organic matter.
A região cacaueira do sul do estado da Bahia (Brasil): crise e transformação
Authors: Bahia de Aguiar Paulo César , De Moura Pires Mônica
Published: April 2019

Este artigo apresenta uma breve visão da recente transformação sofrida pela Microrregião Cacaueira da Bahia (Brasil), com ênfase nos principais fatores endógenos e exógenos que contribuíram para o processo de transformação regional. No percurso metodológico, foram feitos levantamentos (i) de artigos publicados em revistas científicas; (ii) de artigos disponíveis em portais de periódicos especializados e livros impressos; (iii) de dados secundários de natureza socioeconômica extraísdos dos sites do Instituto Brasileiro de Geografia e Estatística (IBGE), do Datasus e do PNUD; (iv) além do levantamento de documentos cartográficos (mapa). Por décadas a predominância da monocultura cacaueira marcou substancialmente a construção socioeconômica local. A última das três principais crises da lavoura cacaueira contribuiu significativamente para que ocorressem mudanças na paisagem tanto ruralmente quanto socioeconomicamente, o que imputou um processo de reorganização socioeconômica e gerou uma ressignificação dessa microrregião. Os principais fatores endógenos identificados foram: forte crise na cacauicultura em razão de estiagens; podridão parda e infestação pela praga crinipellis perniciosa (vassoura-de-bruxa); falta de modernização da produção; descapitalização e endividamento dos cacauicultores; e falências de empresas industriais e comerciais. Os principais fatores exógenos identificados foram: instabilidade macroeconômica; superproduções de cacau em outros países; diminuição dos preços do produto; mudanças estruturais no Brasil; transformações em razão da globalização.Ideias excepcionais: artigo de investigação que se propõe a contribuir para os estudos regionais a partir de uma breve análise da recente transformação pela qual a microrregião cacaueira do sul do estado da Bahia (Brasil) passou e a consequente contribuição dessa mudança para ressignificar a microrregião.
Concentración/dispersión en Santa Fe, Argentina: problemáticas e interrogantes sobre los procesos urbanos contemporáneos en una ciudad media de América Latina
Authors: Rausch Gisela Ariana , Martínez Irene , Nardelli Mariana Lis , Szupiany Estefanía
Published: April 2019

Se discuten problemáticas territoriales contemporáneas en Santa Fe, Argentina, relativas a procesos de concentración y dispersión urbana. Se sostiene que aquellas son la manifestación de estrategias neoliberales de mercantilización espacial, que responden en parte a lógicas globales y a características comunes de las ciudades de América Latina. Se busca dar cuenta del modo en que las lógicas neoliberales globales se cristalizan en contextos locales y, particularmente, en una ciudad de tamaño medio. Los resultados exponen especificidades de los procesos de producción espacial en la última fase del capitalismo, expresadas en el aumento de la marginalidad socioeconómica, la conformación de enclaves urbanos, las urbanizaciones difusas sobre ejes viales y los procesos de verticalización.Ideas destacadas: artículo de reflexión que aborda los modos específicos en que se manifiestan las políticas neoliberales globales en el caso de la ciudad de Santa Fe (Argentina), ciudad que no manifiesta una metropolización desarrollada, pero posee dinámicas de concentración y dispersión en el nivel regional.
Tres versiones de la orfandad en la poesía de César Vallejo
Authors: Rodríguez Zapata Irma Aniela
Published: April 2019

En la vasta obra poética de César Vallejo, es posible identificar la ausencia y la nostalgia del tiempo pasado como registros temáticos presentes con cierta frecuencia. El presente artículo estudia el concepto de orfandad a través de tres variaciones del desamparo en la poesía de Vallejo. Para ello, se examinan aquí elementos tales como el espacio habitado, la figura de la madre y los paraísos perdidos, con la finalidad de indagar y contrastar las diferentes manifestaciones de la orfandad en el universo vallejiano.

Palabras clave: orfandad, ausencia, César Vallejo, poesía, paraísos perdidos, espacio habitado.
Effects of aflatoxin B1 on histopathological structure of immunocompetent organs in mulard ducks
Authors: Groseva N. , Valchev I. , Hristov Ts. , Lazarov L. , Kanakov D. , Binev R.
Published: April 2019

Abstact. The aim of the present experiment was to investigate the toxic effects of aflatoxin В1 (AFB1) on immunocompetent organs (thymus, spleen, bursa of Fabricius) morphology. Also, the possibility for prevention of toxic effects of AFB1 by feed supplementation of a mycosorbent (Mycotox NB) was studied. The experiments were conducted with 4 groups of 20 10-day-old mulard ducks: group I – control, fed a standard compound feed according to the species and the age; group II – experimental, whose feed was supplemented with 0.5 mg/kg. AFB1, group III – experimental, supplemented with 0.8 mg/kg AFB1 and group IV – experimental, supplemented with 0.5 mg/kg AFB1 and 2 g/kg Mycotox NG. The duration of the experiments was 42 days. Atrophy and degenerative changes were observed in immunocompetent organs of birds from groups ІІ and III. The supplementation of the feed with 2 g/kg Mycotox NG resulted in partial neutralisation of deleterious effects of AFB1 on severity of histological lesions (considerably slighter lymphoid follicle rarefaction).
Effect of off-farm work on agricultural productivity: empirical evidence from northern Ghana
Authors: Anang B.T.
Published: April 2019

Abstract. In recent years, there has been increasing recognition of the importance of income diversification to agrarian households in developing countries. Empirical evidence of the effect of farm household income diversification on agricultural productivity remains scanty and inconclusive. An important policy question concerns the effect that farmer participation in off-farm work has on agricultural productivity. This paper answers that question by examining the factors that explain the decision of farm household heads to work off-farm and how this impacts farm productivity using a sample of 300 rice producing households in northern Ghana. Endogenous switching regression model supported by a treatment effect model was used to empirically assess the effect of off-farm work on agricultural productivity. Results show that engagement in off-farm work has a robust and positive impact on rice productivity. Farmers’ choice to work outside the farm thus contributed significantly to rice productivity of smallholders, confirming the role of income diversification in contributing to agricultural productivity of agrarian households.
Zoo-hygienic assessment of lighting in semi-open freestall barns for dairy cows
Authors: Dimov D.
Published: April 2019

Abstract. The aim of the present study was to perform a zoo-hygienic assessment of lighting (natural and artificial) in different technological zones (stalls, manure and feed alleys) in semi-open freestall barns for dairy cows. The survey was conducted over a period of one year in 3 production buildings from 3 cattle farms located in three different areas of Southern Bulgaria - Stara Zagora District, Haskovo District and Plovdiv District. The building’s parameters were as follows: building No.1 - capacity 120 cows, 60.00/18.00/3.00m, 1080m2; building No.2 - capacity 120 cows, 66.00/18.00/3.00m, 1188m2 and building No.3 - capacity 500 cows, 90.00/45.00/3.30m, 4050m2. The premises lighting was measured with two combined apparatuses (Lutron EM-9300SD, 0-20000 lux and PU 150, 0-100000 lux), twice a month at 10.00, 12.00, 14.00, 16.00 and 18.00h at a height of 1m from the floor of the three technology zones. Summarized for all buildings, the light level varies widely by buildings, by seasons, by hours of reporting and by technological zones with limit values between 1 and 9810 lux. In all barns the most intense was the light above the feed alleys, followed by stalls and manure alleys; by hours of reporting during the day the level of lighting above the three technological zones was higher at midday (12.00-14.00h) compared to morning (10.00h) and afternoon (18.00h). Buildings No.1 and No.2 with a smaller built-up area provide more intensive lighting over all technological zones throughout all seasons compared to building No.3 with bigger built-up area: from 7.34 to 13.8 times over stalls, from 3.22 to 5.62 times over manure alleys and from 2.79 to 8.00 times over feed alleys. In buildings No.1 and No.2 there were prerequisites at least 16 hours of day light (photoperiod) to be provided during summer, autumn and spring, while in the winter months up to 8.00am and after 6.00pm the used artificial lighting was with low intensity and cannot provide the recommended over 160 lux intensity of the light. In building No.3 during most of the day for all seasons, the level of lighting above stalls and manure alley where the animals stay the longest time, the lighting level was lower than 160 lux. The factors ‘building’, ‘season’ and ‘hour of the day’ had a statistically significant effect (P<0.05-0.001) on the level of lighting in the three technological zones in the studied buildings. Of the associated factors, only the combination ‘season*hour of reporting’ had no significant effect on the lighting in the zones above the stalls and manure alleys.
Colour and rehydration properties of bay leaves dried by convective and microwave methods
Authors: Polat A. , Izli N.
Published: April 2019

Abstract. This study aims to evaluate the effect of the convective and microwave dying methods on the colour parameters (L*, a*, b*, C,  and ΔE) and rehydration ratio of bay leaves. Drying experiments were conducted using 350 and 460W of microwave powers and air temperatures of 50, 60 and 70C. Different microwave powers show significant effect on colour of dried bay leaves. Increasing microwave power, a* (redness/greenness),  (hue angle) and ΔE (total colour changes) values increased whereas L* (lightness), b* (yellowness/blueness) and C (Chroma) values decreased. For the convective drying, although there are changes in the values of the colour parameters (L*, a*, b*, C and ), there are no significant differences in the values of the total colour changes (ΔE) statistically (P>0.05). The effect of microwave power levels and air temperature on rehydration characteristics was determined. It was found that the rehydration ratio values decreased with an increasing temperature and increasing power levels. The highest rehydration ratio was recorded for the samples dried at 350W and the lowest ratio was seen in a sample dried at 70°C. Microwave drying can be a practical drying process, an alternative to convective drying for drying bay leaves.
Effects of storage duration and bulb sizes on physiological losses of Agrifound light red onion bulbs (Allium cepa L.)
Authors: Abubakar M.S. , Maduako J.N. , Ahmed M.
Published: April 2019

Abstract. The effect of storage duration and bulb sizes on physiological losses of the Agrifound light red onion bulbs stored in an Improved Naturally Ventilated Storage Structure-INVSS (constructed using locally available materials like; sand, cement, wood, corn stalks, wire mesh and grasses) under room condition was studied in 2012. Dry and wet bulb thermometers were installed to measure ambient temperature and relative humidity. Wind velocity was measurement by hand held Anemometer. The onion bulb samples were sorted and graded into three standard size categories (small: <50mm; medium: 50-70mm and jumbo: >70mm in diameter) and kept in the INVSS at the Department of Agricultural and Environmental Engineering Research Farm of Modibbo Adama University of Technology (MAUTECH), Yola. The samples were monitored and data taken on a daily basis for a period of twenty (20) weeks. The data were analyzed with ANOVA in CRD and the means were separated using LSD at p<0.05. The results indicated that storage duration had significant effects (p≤0.05) on weight, rot and sprout losses. Jumbo size onion bulbs had the highest Storage Weight Loss (SWL) by a mean of 5.1%, followed by medium and small size onion bulbs with means of 4.8% and 4.2%, respectively. Storage Sprout Losses (SSL) studied in the three of onion bulb sizes showed higher SSL among the small size Agrifound light red variety than the medium size onion bulbs with respective mean values of 5.0% and 3.8%, while the least value of SSL (2.6%) was observed in Jumbo size onion bulbs. Similar comparison was also made in terms of Storage Rot Losses (SRL) and it showed that relatively higher SRL among the Jumbo size onions (3.3%), followed by medium sizes (3.1%) while the least was observed from the small sizes (2.3%). The findings recommend that the INVSS should be used to store Jumbo and small size onion bulbs for at least 5 months to achieve minimum storage losses. Though, it is not cost effective to store medium size onion bulbs in the INVSS for more than 4 months.
Hydatid disease of pancreas: A case report
Authors: Deák János , Zádori Gergely , Csiszkó Adrienn , Damjanovich László , Szentkereszty Zsolt
Published: April 2019

Primary pancreatic hydatid disease is extremely rare. Diagnosis of the disease is difficult because hydatid cysts can be confused with a pseudocyst or neoplastic cystic diseases. Authors report a case of a surgically treated hydatid disease of the uncinate process of pancreas. In a 34-year-old patient with minor symptoms, a cystic disease of the pancreas was accidentally identified. CT scan revealed a multivesicular cystic mass with a maximum of 13-cm diameter and with a calcificated wall. During laparotomy, the uncinate process of pancreas was resecated and the cystic lesion was enucleated. Patient was recovered without complications and recurrence of the disease. There must be a suspicion of hydatid disease when cysts are identified in good conditioned, asymptomatic patients, or in case of wall calcification or multivesicular cysts revealed by radiological images. Surgical procedures are recommended in uncertain diagnoses too, because differentiation preoperatively between cystic pancreatic lesions is often impossible.
Attachment and problematic Facebook use in adolescents: The mediating role of metacognitions
Authors: Marino Claudia , Marci Tatiana , Ferrante Lucrezia , Altoè Gianmarco , Vieno Alessio , Simonelli Alessandra , Caselli Gabriele , Spada Marcantonio M.
Published: April 2019

Background and aims

Recent research used attachment theory and the metacognitive tenet as frameworks to explain problematic Facebook use (PFU). This study aims to test, in a single model, the role of different attachment styles and metacognitions in PFU among adolescents.

Methods

Two separate studies were conducted in order to establish the link between security (Study 1) and insecurity (Study 2), metacognitions, and PFU. A total of 369 and 442 Italian adolescents (age: 14–20 years old) participated in Study 1 and Study 2, respectively.

Results

Path analyses revealed the relative importance of different attachment dimensions with mother and father in predicting PFU and the mediating role of metacognitions between attachment styles and PFU.

Discussion and conclusion

In conclusion, since attachment styles and PFU may significantly affect adolescents’ development and well-being, the results of this study may provide some practical indications for researchers and practitioners.
Social Resources and Risks of Industrial Revolutions 4.0 in Russia
Authors: Gusov Auzbi , Repkina Olga
Published: April 2019

The article analyzes the main social prerequisites for the implementation of the new industrial revolution in Russia, as well as the social risks arising in this process. The analysis of the main approaches to the understanding of the essence and the main consequences of the industry 4.0 is given, the role of various social groups playing a leading role in the implementation of the revolutionary technological leap is revealed. In this regard, the features of social processes affecting the scientific and technical intelligentsia, the sphere of research and development, innovative entrepreneurship in modern Russia are studied. The fourth industrial revolution is seen as a stage of socio-economic progress with its inherent social problems and risks, such as the widening of the gap between the income on capital and the income of hired workers; increasing income inequality between individual groups of employed and unemployed people within countries due to changes in the structure of the labor market; a significant increase in unemployment in certain segments of the labor market due to automation and robotization of labor and the disappearance of many professions; population aging due to increased life expectancy. It was noted that in Russia there are various basic social resources for successful entry into the process of the fourth industrial revolution, and conditions have developed for a fairly rapid qualitative renewal of the Russian economy and increasing its competitiveness, but there are significant social risks associated with insufficient maturity of individual elements of the social system.
The Trends and Prospects of Leasing Development as a Relevant Financial Tool of Investments in the Southern Regions of Russia
Authors: Kuzmina Emma , Kuzmina Elina
Published: April 2019

Leasing owing to the unique economic essence is considered to be a booster for economic, innovation and investment business activity of any level. In the conditions of competition, economic subjects are constantly in search of innovative approaches to business operations and effective distribution of financial resources.
This determines the demand for leasing as an efficient way to make investments into business. The relevance of the research regarding prospects of leasing development at the regional level does not raise doubts as the issue of sources of new investments into the real sector of Russian economy is particularly urgent today. Consequently, one of the ways to solve this issue is to apply new financial instruments of production, investment leasing in particular. In modern Russian economy the real investments can be raised by means of leasing which are quite necessary for modernization of fixed assets in various branches, including those in the most vulnerable links of the Russian economy.
This paper presents the results of analyzing a tendency and features of leasing market development on the national and regional levels. The authors have given an assessment of investment climate in the Southern regions and systemized the factors on the basis of which both the general risks and the specific regional risks are marked out.
As a result of assessing the experience of leasing functioning, some regional features have been revealed, drivers and development prospects of the leasing mechanism in the southern regions hev been defined. Furthermore, the positive approaches which should be put into practice have been revealed. Some points of growth ahave been defined in various segments of business based on the influencing support factors. As examples of growth drivers we can consider auto leasing, leasing of agricultural machinery, operating leasing, leasing for individuals and a financial supermarket.
On the basis of generalization of possible ways that we can use to develop the regional leasing market there are directions to improve the realization of leasing mechanism on the regional level which can be used in practice.
Formation of the Knowledge Economy in Russia: Problems and Solutions
Authors: Karnaukh Irina
Published: April 2019

For humanity, the 21st century is marked by a transition to a new technological order, which is characterized by giving great importance to management technologies and the development of non-productive areas of activity (science, education, health care, culture). This transition coincides with the transition to a knowledge economy, for which knowledge, innovation and human capital are of paramount importance. For Russia, the study of the problems of the formation and development of the knowledge economy is particularly relevant. According to a number of researchers, it is too early to talk about the formation of the knowledge economy in Russia. The author highlights the list of problems hindering the development of the knowledge economy in our country, namely: low level of R&D funding, low share of domestic R&D costs in GDP, significant predominance of public funds in the structure of R&D sources of funding, imbalance in the financing of fundamental and applied scientific research, the preservation of negative growth rates of the main indicators of postgraduate and doctoral studies, “brain drain” and “ideas leakage”, the absence of a common conception for the development of education, the inconsistency of the education system with the requirements of the labor market, a drop in the quality of school and higher professional education, an insufficient level of funding for education in Russia, and the problem of professional selection in pedagogical universities. The present article sets out the author’s view on solving these problems. In particular, the author argues that to tackle the problem of insufficient funding for science and education in Russia, it is necessary to create such mechanisms that would, on the one hand, diversify the sources of funding for science and education, and on the other hand, let the State to play the main role in these areas.
Severe Epididymo-Orchitis and Encephalitis Complicating Anti-PD-1 Therapy
Authors: Quach Henry T. , Robbins Charles J. , Balko Justin M. , Chiu Charles Y. , Miller Steve , Wilson Michael R. , Nelson George E. , Johnson Douglas B.
Published: April 2019

Background

Immune checkpoint inhibitors such as pembrolizumab and nivolumab have emerged as active treatment options for patients with many cancers, including metastatic melanoma, but can also cause symptomatic or life-threatening immune-related adverse events, including encephalitis. Epididymitis and orchitis are rare complications of these therapies.

Case Presentation

We describe herein a patient with metastatic melanoma who developed epididymo-orchitis followed by encephalitis while receiving pembrolizumab. The patient developed testicular pain and fever after his third dose of pembrolizumab; ultrasound evaluation demonstrated bilateral epididymo-orchitis. He then developed headaches, fever, and altered mental status over the next week and was admitted to the hospital. Lumbar puncture revealed inflammatory changes consistent with meningoencephalitis; he did not improve with broad-spectrum antibiotics, and an extensive workup for infectious etiologies, including cerebrospinal fluid testing using a clinical metagenomic next-generation sequencing assay, was negative. He received high-dose steroids for suspected autoimmune encephalitis, and both his orchitis and meningoencephalitis improved rapidly after one dose. He fully recovered after a 5-week taper of oral steroids.

Discussion

Here, we report a case of epididymo-orchitis complicating immune checkpoint inhibitor therapy. This patient subsequently developed severe encephalitis but rapidly improved with steroids. Clinicians should be aware of rare complications of these agents.

Key Points

Epididymo-orchitis is a rare and potentially life-threatening complication of anti-programmed death protein 1 (anti-PD-1) therapy. For patients on anti-PD-1 therapy who develop either epididymo-orchitis or epididymitis without clear infectious cause, immune-related adverse events should be considered in the differential diagnosis. If severe, epididymo-orchitis related to anti-PD-1 therapy may be treated with high-dose corticosteroids.
A systematic framework for formulating convex failure envelopes in multiple loading dimensions
Authors: Suryasentana Stephen K. , Burd Harvey J. , Byrne Byron W. , Shonberg Avi
Published: April 2019

The failure envelope approach is widely used to assess the ultimate capacity of shallow foundations for combined loading, and to develop foundation macro-element models. Failure envelopes are typically determined by fitting appropriate functions to a set of discrete failure load data, determined either experimentally or numerically. However, current procedures to formulate failure envelopes tend to be ad hoc, and the resulting failure envelopes may not have the desirable features of being convex and well-behaved for the entire domain of interest. This paper describes a new systematic framework to determine failure envelopes – based on the use of sum of squares convex polynomials – that are guaranteed to be convex and well-behaved. The framework is demonstrated by applying it to three data sets for failure load combinations (vertical load, horizontal load and moment) for shallow foundations on clay. An example foundation macro-element model based on the proposed framework is also described.
Ações de rastreio dos cânceres de mama e do colo do útero em uma região do Paraná
Authors: Gomes Eliane Da Silva , Rodrigues Sabrina De Almeida , Dantas Karen Fernanda de Deus , Nishida Fernanda Shizue , Bernuci Marcelo Picinin
Published: April 2019

Justificativa e objetivos: Mundialmente é significativa a mortalidade por câncer de mama e câncer do colo do útero. No Paraná estas incidências estão aumentando, crescendo a necessidade de implementação de rastreio para tratamento precoce para melhorar chances de cura. Para melhor administrar os recursos é necessário conhecer como estão sendo feitos esses exames. O objetivo do presente trabalho foi realizar análise da frequência de realização das ações de rastreio dos cânceres de mama e do colo de útero, com mamografias e colpocitologias, nos anos de 2010 a 2013 e 2006 a 2013, respectivamente, na região do “Consórcio Público Intermunicipal de Saúde do Setentrião Paranaense” (CISAMUSEP), e estimar as coberturas tanto da região do CISAMUSEP quanto do Paraná e compara-las, por faixas etárias das pacientes. Métodos: Foi um estudo transversal utilizando dados secundários do SISMAMA e do SISCOLO. Para calcular coberturas estimou-se uma porcentagem de usuárias do SUS, não alcançando coberturas recomendadas. Resultados: Como resultado foi encontrado um aumento das mamografias de 2010 a 2012 e decréscimo em 2013. Em todos os anos 70% das mulheres que realizaram mamografias tinham de 40 a 59 anos, somente no ano de 2013 realizou-se mais exames entre as mulheres de 50 a 59 anos de idade do que mulheres de 40 a 49 anos. As colpocitologias aumentam e diminuem repetidamente de ano a ano. Sendo que cerca de 80% foram feitas em mulheres com idade de 25 a 64 anos. Conclusão: Comparando-se as coberturas do CISAMUSEP com o estado do Paraná, o primeiro tem melhor desempenho com mamografias e pior desempenho com colpocitologias.
Características da constipação funcional em crianças de zero a doze anos atendidas em um ambulatório de gastroenterologia pediátrica
Authors: Bastos Marília Dornelles , Pereira Bruna Fernandes , Chaves Jessica , Tabile Patricia , Pereira Luciane Mattos
Published: April 2019

Justificativa e Objetivo: A caracterização da constipação orienta uma abordagem preventiva. O estudo tem por objetivo conhecer as características da constipação nas crianças atendidas em ambulatório especializado. Métodos: Trata-se de um estudo transversal, quantitativo e descritivo, com aplicação de questionário durante o primeiro atendimento ambulatorial de gastroenterologia pediátrica, entre agosto de 2014 a outubro de 2015. Na seleção dos pacientes utilizou-se os critérios de ROMA IV e relato de hematoquezia e disquezia. Realizou-se um perfil clínico-epidemiológico das crianças, prevalência dos principais sintomas, comorbidades e tratamentos prévios. Na história alimentar incluiu-se questões sobre satisfação dos pais/responsáveis quanto a ingestão de alimentos e líquidos pela criança. A análise e o processamento dos dados foram realizados com o programa Statistical Package for the Social Sciences (SPSS) versão 22.0. Resultados: Queixas de constipação ocorreram em 29% dos novos pacientes. Média de 4,3 anos com início dos sintomas, majoritariamente no primeiro ano de vida (71,0%). A principal comorbidade foi alergia alimentar e 77,6% já realizavam tratamento. Amamentação exclusiva não ocorreu em 19,4%. A média da idade de introdução da fórmula foi 4,89 meses. A introdução de leite de vaca na dieta foi em média aos 9 meses. A ingestão de frutas e legumes, considerada satisfatória em 25,8% e de água em 57%. Conclusão: O estudo mostrou que crianças com constipação intestinal de um ambulatório especializado apresentam elevada prevalência de início já no primeiro ano de vida. O estímulo ao aleitamento materno e adequada orientação alimentar no desmame ainda é considerada a melhor forma de prevenção.
Resistência aos antimicrobianos: uma revisão dos desafios na busca por novas alternativas de tratamento
Authors: Da Silva Moisés Oliveira , Aquino Simone
Published: April 2019

Justificativa e objetivo: Os antimicrobianos correspondem a uma classe de fármacos mundialmente empregados no tratamento de inúmeras patologias desencadeadas por microrganismos. Nos últimos anos, em decorrência do aumento da resistência bacteriana, principalmente por patógenos potencialmente nocivos para a saúde, têm-se despertado gradativamente a necessidade pela busca de novas substâncias com o intuito de conter as infecções desencadeadas nos ambientes hospitalares e na comunidade. Em razão disso, o desafio é a busca por novas pesquisas relativas às novas substâncias com atividades antimicrobianas ou sob a averiguação que demonstraram notória efetividade quando testados frente às bactérias, comparando-as aos já empregados. Conteúdo: A revisão bibliográfica, pertinente ao assunto, baseada em artigos publicados nas revistas indexadas no Scielo, Science Direct, Bireme, Medline e Pubmed, apontou novos estudos e evidenciaram que há novas substâncias em desenvolvimento ou já disponíveis com significativa atividade antimicrobiana capaz de reduzir, de forma seletiva, alguns microrganismos emergentes ou multirresistentes em um curto período de tempo, bem como ao longo prazo. Conclusão: Visto que há novas fontes naturais sendo exploradas e que podem contribuir para a síntese de novos fármacos com propriedades antimicrobianas, vislumbram-se novos antimicrobianos a serem inseridos no mercado e na prática clínica.
Extrapulmonary TB or sarcoidosis associated with TB? Case report
Authors: Costa Gabriel Domingues , Oliveira Daniele Tailla , Almeida Guilherme Brandão , Pacheco Pereira Hugo Cataud , Da Silva Ana Barbara Scholante , Diniz Jaciara , Silva Pedro Eduardo Almeida
Published: April 2019

Objetivos: O presente relato tem como objetivo discutir o diagnostico diferencial entre tuberculose e sarcoidose. Descrição do caso: Caso de um paciente do sexo masculino, 25 anos, que desenvolveu artrite granulomatosa e osteomielite com inflamação granulomatosa não caseosa sugestiva de sarcoidose. Vinte e quatro meses antes desse relato, o paciente teve resultados laboratoriais positivos para tuberculose pulmonar, no entando, não foi tratado. Conclusão: Demonstramos como é necessário o acompanhamento do paciente após a realização de um teste diagnóstico para tuberculose e o desafio de confirmar um diagnóstico de sarcoidose em um paciente com tuberculose.
O enigma da constituição subjetiva no autismo: uma leitura psicanalítica da autobiografia de Temple Grandin
Authors: Pinto Borges Mayara Yasmim , Castro Maria Luiza Sarno
Published: April 2019

Esta pesquisa tem como objetivo analisar a autobiografia de Temple Grandin, com base na teoria da alienação e separação elaborada no primeiro ensino de Lacan durante o Seminário 11. O estudo contou com o método qualitativo, a partir da análise documental do livro "Uma menina estranha: Autobiografia de uma autista". Os resultados da análise apontam que apesar de cada autor ter uma particular leitura do autismo, que ainda gera debates, eles convergem em alguns aspectos, como o diagnóstico diferencial do autismo e psicose e que na estruturação subjetiva da criança autista, o cerne da questão está no processo da alienação, sendo possível observar sinais do autismo desde a primeira infância. Concluindo que apesar de não haver uma melhor teoria a respeito do autismo, devendo se levar em consideração o caso a caso do paciente em questão, a análise da autobiografia de Temple Grandin aponta para a hipótese apresentada por Maleval da alienação parcial.
Meaningful Learning and Its Implications for Language Education in Vietnam
Authors: Hung Bui Phu
Published: April 2019

This paper attempts to make an argument for meaningful learning as an essential factor in the teaching of English as a foreign language. Meaningful learning rests its theories against cognitive processing. While contemporary literature shows knowledge of language in general is essential for second language use, this research is mainly concerned with ways of improving students’ language use. It has proved that meaningful learning facilitates the retention of knowledge as it makes learners organize their knowledge logically. In the classroom, the teacher should offer activities that relate the new input to learners’ existing knowledge, for which cognitive engagement is required. In English language teaching, it is important for teachers to know that learner-centeredness should be applied because they are the ones who process knowledge. This paper begins with an overview of different approaches of foreign language teaching, then presents theories in which meaningful learning is grounded and rooted. The discussion of how one’s knowledge of a first language is essential for foreign language learning is given prior to giving implications of meaningful learning in the Vietnamese context.
Impact of preventive oral health interventions during the prenatal care on preterm delivery, an integrative review protocol. v1
Authors: Dutra Vieira Cristina , Nayla de Assis Aguiar Andreza , Aparecida Silva de Oliveira Lima Camila , Reis Zilma
Published: April 2019

Background: Spontaneous preterm birth is a worldwide concern due to the impact on infant mortality. Good quality of antenatal care pregnancy has the potential to reduce the rate of prematurity and improve neonatal outcome. Periodontal disease suppose to affect preterm labor. The impact of interventions to promote the oral health of pregnant women in the prevention of preterm birth is still controverse. Objective: To assess evidence on the impact of oral health interventions during prenatal care in preventing spontaneous preterm birth. Methods: A comprehensive integrative literature review to respond to the primary research question: Which the interventions to promote oral health during antenatal care associated with higher duration of gestation? First version, March-09-2019. Stage of review: Ongoin
Optimalisasi Pelayanan Penggunaan Ruang Sidang Dengan Media Online Berbasis Teknologi Informasi Di Lingkungan Direktorat Jenderal Guru Dan Tenaga Kependidikan Kementerian Pendidikan Dan Kebudayaan
Authors: Samto Samto , Adman Adman
Published: April 2019

ABSTRAKOptimalisasi pelayanan lembaga publik kepada masyarakat merupakan kewajiban yang harus selalu ditingkatkan. Optimalisasi pelayanan kepada masyarakat dan stakeholder menjadi dambaan bagi pengelola lembaga. Optimalisasi pelayanan adalah sebuah upaya untuk selalu meningkatkan dan memperbaiki kualitas dan kuantitas pelayanan dengan melibatkan komponen-komponen yang saling berkaitan satu sama lain. Optimalisasi pelayanan dapat ditempuh dengan berbagai cara, baik tradisional, maupun modern. Seiring dengan perkembangan zaman bentuk-bentuk pelayanan pada lembaga pemerintahan telah berubah bentuk dan orientasinya, dari cara-cara tradisional kearah modern dengan mempergunakan alat-alat atau media elektronik. Penggunaan media elektronik telah berkembang pesat seiring dengan kemajauan teknologi, informasi dan komunikasi. Penggunaan media elektronik dalam berbagai bidang telah membawa dampak kemudahan, kecepatan, transparansi dan akuntabilitas dan mampu meningkatkan pelayanan publik sehingga mampu mewujudkan good governance.Kata kunci: optimalisasi layanan, media online, teknologi informasiOptimizing services of public institutions to the public is an obligation that must always be improved. Optimizing services to the community and stakeholders is a dream for the management of the institution. Service optimization is an effort to always improve and improve the quality and quantity of services by involving components that are interrelated with each other. Optimization of services can be reached in various ways, both traditional and modern. Along with the development of the times the forms of service in government institutions have changed their form and orientation, from traditional ways towards modernity using tools or electronic media. The use of electronic media has developed rapidly along with the advancement of technology, information and communication. The use of electronic media in various fields has brought the impact of ease, speed, transparency and accountability and is able to improve public services so as to be able to realize good governance.Keyword : service optimization, online media, information technology
LOCAL RECEPTIVITY CLIMATES AND THE DYNAMICS OF MEDIA ATTENTION TO PROTEST
Authors: Rafail Patrick , McCarthy John D. , Sullivan Samuel
Published: April 2019

Research on media attention to social movements generally examines a small sample of media outlets and a diverse sample of protest events. This approach has produced significant insight into the type of protests covered by the media but has minimized the role of media organizations. This study flips the approach taken by prior work: we examine coverage patterns of 1,498 nationally coordinated but highly comparable vigils against the Iraq War in 426 U.S. newspapers. We show that protest coverage is shaped by local receptivity climates, which emphasize the organizational and contextual features of media environments that influence media attention. We show that larger newspapers, those that covered the Iraq War more extensively, and those in areas supporting the Democratic Party devoted more attention to the vigils. Our results bridge the gap between the features of protest events that are newsworthy and the organizational routines that structure journalistic work.
MAKING GOOD NEWS: WHAT EXPLAINS THE QUALITY OF COVERAGE OF THE CIVIL RIGHTS MOVEMENT
Authors: Amenta Edwin , Elliott Thomas Alan , Shortt Nicole , Tierney Amber C. , Türkoğlu Didem , Vann Burrel
Published: April 2019

When social movement organizations receive extensive newspaper coverage, why is it sometimes substantive and sometimes not? By “substantive,” we mean coverage that reflects serious treatment of the movement's issues, demands, or policy claims. Scholars agree that the news media are key to movement organizations' influence, helping them alter public discourse and effect political change, but often find that protests are covered nonsubstantively. Employing insights from literatures on historical institutionalism, the social organization of the news, and the consequences of movements, we elaborate an “institutional mediation” model that identifies the interactive effects on coverage of news institutions' operating procedures, movement organizations' characteristics and action, and political contexts. Although movement actors suffer compound legitimacy deficits with journalists, the institutional mediation model identifies the openings news institutions provide, the movement organizational characteristics, the forms of collective action likely to induce substantive news treatment, and the political contexts that will amplify or dampen these effects. We derive four interactive hypotheses from this model, addressing the effects of organizational identities, collective action, and political contexts on news outcomes. We appraise the hypotheses with comparative and qualitative comparative analyses of more than 1000 individually coded articles discussing the five most-covered organizations of the 1960s U.S. civil rights movement across four national newspapers. We find support for each hypothesis and discuss the implications for other movement organizations and the current media context.
“IT'S A RAT RACE”: THE IMPACT OF IDEOLOGICAL IMPRINTING ON MICROLEVEL EXPERIENCES OF MOVEMENT PROFESSIONALIZATION
Authors: Owen Cam Nguyen
Published: April 2019

Movement professionalization has mainly been conceptualized as a mesolevel process, with past research stressing differences between groups. Few studies have accounted for why activists in the same organization might have drastically dissimilar experiences. Using interviews with thirty left-wing former and current movement professionals, the article integrates recent scholarship on activist pathways to explain intragroup variations. Findings show that activists who saw professionalization as a dilemma were influenced by the ideological imprinting, i.e., exposure to ideals of “grassroots” mobilization they encountered during the formative years of their activist careers, rather than their current organizational characteristics. Also, while the professionalization literature focuses on tactical moderation, activists emphasized a different problem. They saw external patronage as “tainted” money and an impediment to one-on-one relationship building with constituents. This study highlights the importance of incorporating activist trajectories into the professionalization literature and understanding aspects of movement careers that hinder participation along with those facilitating it.