bluuebunny/crossref_metadata_2025 huggingface dataset:
A pilot study of twice-weekly group-based written exposure therapy for veterans in residential substance use treatment: effects on PTSD and depressive symptoms
Authors: Van Doren Natalia , Chang Fang-Hsi , Nguyen Amanda , McKenna Kevin R. , Satre Derek D. , Wiltsey-Stirman Shannon
Published: February 2025

Background

Posttraumatic stress disorder (PTSD) is highly comorbid with substance use disorders (SUDs), resulting in high prevalence of PTSD among individuals in residential SUD care. However, there is limited research on integrating trauma treatment into residential SUD care settings. The aim of the present project was to conduct an initial evaluation of the effects of group-based Written Exposure Therapy (WET) on PTSD and depressive symptoms that was integrated into programming for individuals in residential SUD treatment.

Methods

Participants were 48 Veterans with comorbid PTSD-SUD from a 28 day residential SUD program at a Veterans Affairs Medical Center. Eligible participants were enrolled in 5 sessions of WET, delivered twice-weekly in an adapted group format. PTSD symptoms and depressive symptoms were assessed at each session with the Posttraumatic Stress Disorder Checklist, DSM-5 version (PCL-5) and the Patient Health Questionnaire (PHQ-9).

Results

Over 5 months, 76.2% of the target population were successfully enrolled. Of the enrolled sample, 48 participants, 92% (n = 44) completed 3 sessions, while 56% (n = 28) completed 5 sessions. Generalized Estimating Equations (GEE) showed significant within-person reductions in PTSD symptoms over time, with an average decrease of 3.18 per session (χ² = 23.21, p = .006) and moderate effect sizes (d = 0.46 and d = 0.51 at mid- and post-treatment). In addition, there were significant reductions in depressive symptoms within-persons over time, with an average per-session reduction of 1.13 (χ² = 23.10, p = .006).

Conclusion

Findings demonstrate that brief, group-delivered WET is feasible and shows promise for addressing PTSD and depressive symptoms in residential SUD treatment. Results of the present evaluation could inform further efficacy testing and implementation of PTSD treatment into residential SUD settings.
Highly effective energy transfer in the autotroph-heterotroph symbiosis: insights from compound-specific isotope analysis of amino acids
Authors: Li Jincen , Shibuya Mio , Takizawa Yuko , Chikaraishi Yoshito
Published: February 2025

Many species establish symbiotic partnerships with different organisms to benefit energetically from living together to fit into environments, and such symbiosis is frequently found in the modern ocean as well as throughout Earth’s history. For example, coral reef ecosystems represent one of the most productive and biologically diverse ecosystems in the modern ocean, which is simply explained by an assumption that many autotroph-heterotroph symbiotic species found in there increase the efficiency of trophic transfer from primary producers (i.e., algal symbionts) to primary consumers (i.e., animal hosts), and that such high efficiency may be propagated to entire food webs. However, this high efficiency has not been proved and illustrated with quantitative data in the trophic transfer of photosynthates from algal symbionts to animal hosts. In the present study, we measured the energetic balance between degradation and biomass growth, which is a major factor of the efficiency of trophic transfer, based on the analysis of stable nitrogen isotope ratios of amino acids for several species including sea anemones, stony corals, zoanthids, and soft corals, that were bred under an autotrophic condition in a laboratory aquarium. The results confirm that the symbiosis indeed provides highly effective energy transfer of algal photosynthates to animal hosts, and allow us to quantify that the energy transfer in the symbiosis increases by approximately twice of that when non-symbiotic herbivorous species feed on primary producers. These results induce a new perspective that the effective energy transfer driven by symbiosis is a critical factor controlling the development of highly productive and biologically diverse ecosystems in the modern ocean as well as throughout Earth’s history.
Stepwise autonomous orbit determination of large LEO constellations by GNSS observations with partial inter-satellite ranging
Authors: Yang Yuanxi , Song Xiaoyong
Published: February 2025

Large constellations composed of a great amount of Low Earth Orbit (LEO) satellites are widely applied in satellite communication, remote sensing, augmented satellite navigation, environment monitoring, and so on. The satellite Orbit Determination (OD) is critical for the various function realization of the large constellation. Three different stepwise autonomous OD strategies for the large constellation of LEO satellites are proposed based on the spaceborne Global Navigation Satellite System (GNSS) observations and Inter-Satellite Link (ISL) range measurements, including the stepwise OD with both GNSS and ISL range measurements, stepwise OD with ISL range constraints, and an adaptive stepwise OD with both kinds of measurements. All of the three proposed stepwise autonomous OD approaches first estimate the initial orbit parameters for each satellite utilizing the spaceborne GNSS observations based on either a kinematic or dynamic OD strategy. The correction vector for the orbit parameters of each satellite is then individually calculated using the partial ISL range observations or ISL range constraints. The difference of the adaptive stepwise OD algorithm is that the covariance matrix of the predicted orbit parameters based on the dynamic model is modified by an adaptive factor. The LEO satellite parameters estimated with the stepwise OD strategies are equivalent to those obtained with the related integrated OD strategies. The main advantages of the proposed stepwise OD estimators are: (1) the orbit parameters of each satellite can be estimated in parallel, reducing the OD computational load for a large LEO constellation; (2) the spaceborne GNSS observations and the ILS range measurements in the three proposed approaches can be separately joined the OD procedures, making the parameter estimation flexible; (3) the adaptive stepwise OD mode with an adaptive factor acting on the covariance matrix of the predicted orbit parameters can effectively control the effects of the abnormal dynamic model information on the orbit parameter estimates. The simulation results for different OD strategies are analyzed. It is shown that the Root Mean Square Error (RMSE) of the estimated positions of the LEO satellites using the kinematic OD method is 60.527 cm, assuming the GNSS pseudorange noise of 30 cm. In contrast, the RMSE for the stepwise strategy, which considers only four adjacent ISL range measurements with an accuracy of 5 cm, is 18.287 cm. When the dynamic models for the LEO satellites are adopted, the RMSE of the estimated satellite positions using the stepwise orbit determination is further reduced to 11.340 cm. If the ISI ranging accuracy is better than 5 cm, the results remain nearly the same disregarding the ISL ranges are employed as observations or as constraints in the stepwise OD approaches. If the dynamic model information contains a few outliers, the adaptive stepwise OD can effectively control their effects on the orbit parameter estimates.
Human neuropilin-1 biomarker as predictor of subclinical cardiovascular affection in systemic lupus erythematosus patients
Authors: Soliman Samar Gaber , Yossef Samah Samy , Shahin Shaimaa R. , Serag Dina Mamdoh , Saif Dalia S.
Published: February 2025

Background

Cardiovascular disease (CVD) is recognized as the leading cause of death in patients with systemic lupus erythematosus (SLE). Although the pathways involved in accelerated cardiovascular disease are not yet fully understood, atherogenesis may be dramatically influenced by immune dysregulation in SLE. Evaluating the role of neuropilin-1 (NRP-1) biomarker in early detection of subclinical cardiovascular affection, and as an indicator of disease activity in SLE patients was the aim of this work.

Results

We evaluated serum human Neuropilin-1 (NRP-1) in SLE patients, and controls. We found that serum NRP-1 levels were significantly elevated in SLE patients, particularly in cases of high disease activity, and in those with subclinical cardiovascular affection. About 33% of SLE patients had increased carotid-intimal-medial thikness (CIMT), while 14% had abnormal brachial artery vasodilation response. Regarding SLE instances independent risk factors for subclinical cardiovascular affection included SLE disease activity, duration, body mass index (BMI), systolic and diastolic blood pressure, and serum NRP-1 level.

Conclusion

Human neuropilin-1 biomarker may represent a potential marker for early detection and prediction of subclinical cardiovascular affection in SLE patients at precise and sensitive cutoff point. In addition to its direct relationship to SLE disease activity; thus; it may serve as an advantageous serological indicator for the prediction of SLE disease activity.
Examining the influence of fiber orientation and cross-sectional geometry on the absorption capability of epoxy/carbon composite absorbents
Authors: Chen Yanxue , Zhong Yanxia , Yin Haixia , Wu Zhenghong , Wei Yuting
Published: February 2025

This study investigates the collapse behavior and energy absorption capabilities of epoxy/carbon composite absorbers using finite element analysis (FEA) in ABAQUS software. The analysis focuses on different geometrical cross-sections (circular, square, and octagonal) and various fiber orientations (0°, 30°, 45°, 60°, and 90°). The simulation results are validated against experimental data from previous studies to ensure accuracy. The findings reveal that nonzero fiber orientations induce twisting, altering stress distribution and reducing geometric stability. The highest energy absorption capacity was registered for the circular sections among the investigated geometries; the maximum collapse force for octagonal sections with a fiber orientation of 60° was increased by 35% and 49% with respect to the cylindrical and square sections, respectively. Also, in the case of an octagonal section, the maximum average absorbed energy occurs at a fiber orientation of 51.3°. The octagonal cross-section, especially for fiber orientation of 46.4°, demonstrates a better maximum peak load than the rest of the geometries. In this study, the critical effect of fiber orientation on the collapse behavior and energy absorption was underlined; for instance, a 0° fiber orientation behaves like a soft material, while 90° behaves like a brittle one, providing different modes of collapse. The results indicate how composite materials could be optimized for energy absorption applications.
Revisiting the barometric equation and the extent of a planetary atmosphere
Authors: Grimsditch Marcos , Karpov Victor G.
Published: February 2025

The barometric equation predicts the molecular concentration n(z) exponentially decaying with altitude z. Because the mean free path l = 1/nσ increases exponentially, at high altitudes z, the equation is no longer within the domain of applicability of the standard kinetic theory. Here, we predict the dependence n(z) ∝ z−2 for the case l ≫ L in uniform gravity and n(z) ∝ [ln(1+z/R0)]−2 when z ≫ R0 for a planet of radius R0. It corresponds to a non-stationary planetary atmosphere with hydrogen accretion. The accretion is accompanied by a release of gravitational potential energy that could be the elusive source driving the formation of stellar coronas. Other consequences include slowly decaying tails of planetary atmospheres and periodical hydrogen explosions of white dwarfs.
“We Are Here with Our Rebellious Joy”
Authors: Kurtoğlu Ayça
Published: February 2025

Campus Witches is the name of a group/network of young feminists located at universities in Turkey. The group was born out of the Gezi Park protests of 2013. Their appearance in the feminist movement is novel in that they make up the first and only feminist group identifying themselves with witches. This chapter shows that the Campus Witches' formation can be linked to the history of feminist movement as well as to women's everyday resistances within social and political contexts in which women are rendered powerless. The first part of the chapter presents processes in which women move from spell-crafting subjects to Campus Witches. The second part of the chapter is about women's everyday resistance to male domination, which creates insecurities and uncertainties for women; those practices of resistance prepare the ground for women to adopt a witch identity. The chapter concludes that women's practices associated with being nonrational or evil are a means of creative empowerment.
Effects of oxygen level on thermal tolerance in Amazonian catfishes with bimodal respiration: physiological and behavioural changes
Authors: de Lima Mayara Cristina Moraes , Campos Derek Felipe , Kochhann Daiani , Val Adalberto Luis
Published: February 2025

The degree of tolerance to adverse conditions ultimately shapes a species' vulnerability to environmental changes. Some studies have reported limited thermal tolerance due to hypoxia in fish employing aquatic respiration. However, there is a lack of information regarding the effects of hypoxia on thermal tolerance in fish exhibiting bimodal respiration. A set of Amazonian fish species has adaptations to breathe air when oxygen in water is not enough to fulfil demand. Additionally, loricariid species within this group possess stomach adaptations for air breathing. The Loricariidae family exhibits varying stomach types and observed morphological differences could influence their ability to obtain oxygen from the air. This ability may, in turn, have consequences for the thermal tolerance of these species. Our objective was to assess the effects of hypoxia on thermal tolerance, along with the physiological (whole-animal metabolic rates and mitochondrial respiration) and behavioural mechanisms involved, in two facultative air-breathing species: Pterygoplichthys pardalis and Ancistrus dolichopterus. These species showcase morphological distinctions in their stomachs, with the former having a higher capacity to obtain oxygen from the air. Thermal tolerance in P. pardalis remained unaffected by dissolved oxygen in the water when air access was available but decreased when access to the water surface was restricted, specifically in hypoxic conditions. Conversely, the thermal tolerance of A. dolichopterus decreased below the critical oxygen partial pressure (Pcrit), even with access to air, highlighting their limited ability to obtain oxygen through their adapted stomach. Our results underscore that air breathing enhances thermal tolerance, but this effect is prominent only in species with a higher capacity for air breathing.
The genome sequence of the Jersey Tiger moth, Euplagia quadripunctaria (Poda, 1761)
Authors: Lees David C. , Holland Peter W. H. ,   Natural History Museum Genome Acquisition Lab,   Darwin Tree of Life Barcoding collective,   Wellcome Sanger Institute Tree of Life Management, Samples and Laboratory team,   Wellcome Sanger Institute Scientific Operations: Sequencing Operations,   Wellcome Sanger Institute Tree of Life Core Informatics team,   Tree of Life Core Informatics collective,   Darwin Tree of Life Consortium
Published: February 2025

We present a genome assembly from an individual male specimen of Euplagia quadripunctaria (Jersey Tiger; Arthropoda; Insecta; Lepidoptera; Erebidae). The genome sequence has a total length of 668.40 megabases. Most of the assembly (99.6%) is scaffolded into 31 chromosomal pseudomolecules, including the Z sex chromosome. The mitochondrial genome has also been assembled and is 15.48 kilobases in length.
Polska kancelaria królewska czy system kancelarii centralnych dawnej Rzeczypospolitej?
Authors: Chorążyczewski Waldemar
Published: February 2025

Artykuł przypomina dorobek cyklu czterech spotkań z lat 2002–2009 poświęconych polskiej kancelarii królewskiej, przedstawia i ocenia przyczynkowe badania kancelarii królewskiej pojawiające się od tego czasu. Przewidując i postulując przyszłe badania, autor wskazuje na pożytek poddawania analizie nie tyle kancelarii królewskiej, co systemu kancelarii królewskich, czyli działających w imieniu króla od XIV do XIX w. Powinny one doprowadzić do pojawienia się w perspektywie dziesięciolecia syntetycznego ujęcia, które nie będzie doskonałe, punktowo będzie wręcz kwestionariuszem dalszych dociekań, ale ożywi i ukierunkuje nurt badań polskiej dyplomatyki monarszej.
Wbrew zakazom. Fotografia jako forma oporu w latach 1939–1945. Warszawa, 28 października 2024 r.
Authors: Kwietniewski Mariusz
Published: February 2025

Sprawozdanie z konferencji Wbrew zakazom. Fotografia jako forma oporu w latach 1939–1945. Warszawa, 28 października 2024 r.
Kancelaria królewska między władzą a społeczeństwem. Kraków, 6–7 listopada 2024 r.
Authors: Chorążyczewski Waldemar
Published: February 2025

Konferencja stanowi kontynuację cyklu spotkań poświęconych polskiej kancelarii królewskiej, jakie odbywały się w latach 2002-2009. Jej celem naukowym była odpowiedź na pytanie o dalszy kierunek badań dyplomatyki monarszej w Polsce. Nie ma wątpliwości, że należy zajmować się nie tyle kancelarią koronną, co systemem kancelarii centralnych urzędów Rzeczypospolitej, włączając w to kancelarię koronną, kancelarię litewską i kancelarie ministrów Rzeczypospolitej. Uwzględnić trzeba także kancelarie prywatne monarchów i urzędników państwowych, Trybunał Koronny, Trybunał Litewski, kancelarie sądów ziemskich i kancelarie kościelne, o ile wspomagały funkcjonowanie państwa. Optymalnym modelem badawczym wydaje się analiza funkcjonalna biorąca za punkt wyjścia wyzwania aparatu państwowego, angażujące różne kancelarie zatrudniające kompetentnych pracowników.
Górny, Rafał. Pokaż mi przeszłość „na prawdziwo”. Historia w dokumentach archiwalnych dla dorosłych. Warszawa: Archiwum Główne Akt Dawnych, 2023
Authors: Jablońska Marlena
Published: February 2025

Recenzja książki: Górny, Rafał. Pokaż mi przeszłość „na prawdziwo”. Historia w dokumentach archiwalnych dla dorosłych. Warszawa: Archiwum Główne Akt Dawnych, 2023.
Two Approaches to Cognitive Evaluation: Assessing the Strengths and Limitations of GPCOG and ACE-III
Authors: Mąka Magdalena , Sikora Dominik , Oleksy Piotr , Zając Adam , Zieliński Karol , Papież Łukasz , Góralczyk Ewa , Kamiński Jakub , Buczkowski Bartosz , Wochnik Dagmara
Published: February 2025

Introduction : The aging population highlights age as a key risk factor for dementia and other cognitive disorders. Reliable diagnostic tools are crucial. This review examines the Addenbrooke’s Cognitive Examination-III (ACE-III) and the General Practitioner Assessment of Cognition (GPCOG), focusing on their sensitivity, specificity, and utility in diverse healthcare contexts. 
Purpose of Research: This analysis explores the clinical utility of the Addenbrooke’s Cognitive Examination-III (ACE-III) and the General Practitioner Assessment of Cognition (GPCOG) for diagnosing cognitive disorders, including dementia, emphasizing their use in primary care and specialized settings. 
Materials and Methods : A review of 37 peer-reviewed studies, including clinical trials and validation research, was conducted using databases like PubMed and Google Scholar. Keywords included "GPCOG," "ACE-III," and "cognitive screening." 
Results : ACE-III shows high diagnostic accuracy, with sensitivity and specificity exceeding 93% and 96%. It excels in assessing complex dementia but is time-intensive and requires trained personnel, limiting its use in primary care. Conversely, GPCOG is a quick, user-friendly tool suited for primary care but lacks the depth for detailed diagnostics. 
Conclusions : ACE-III is optimal for detailed evaluations in specialized settings, while GPCOG excels in rapid primary care screening. Combined, they enhance early detection and management of cognitive disorders.
Pain Associated with Endometriosis. A Review of Quality of Life. Psychological Aspects, Career Development, Sexual Health, and Intimate Partner Relationships
Authors: Zubiak Marlena , Byrska Martyna , Barska-Kobylińska Hanna , Langner Sara , Malaka Ewa Katarzyna , Janura Marta , Elias Jagoda , Biesiada Wiktor , Szydłowska Sara , Błaszków Krzysztof
Published: February 2025

Introduction: Endometriosis is a chronic estrogen-dependent inflammatory disease characterized by the presence of tissue resembling the endometrium outside the uterine cavity. It affects approximately 10% of women of reproductive age. The main symptoms include severe pain, reduced fertility, and sexual dysfunction. Treatment includes pharmacotherapy and surgical interventions, depending on the severity of symptoms, the location of lesions, and their extent.
Study Objective: The aim of the study was to assess quality of life, as well as the impact of dyspareunia and other endometriosis-related symptoms on sexual health and intimate partner relationships.
Materials and Methods: Over 60 scientific articles addressing this issue were analyzed. The studies were retrieved from the PubMed platform, spanning the years 2004 to 2024.
Conclusions: The symptoms of endometriosis, along with limited therapeutic options, significantly affect overall quality of life, sexual health, and partner relationships. Based on the available literature and current knowledge, it can be concluded that it is crucial to provide not only medical treatment but also sexological and psychological support.
Are Artificial Sweeteners a Healthier Alternative to Sugar?
Authors: Buszek Julia , Czerniak Piotr , Antoszewska Adrianna , Bargiel Weronika , Bąk Dominika , Wajdowicz Halszka , Warzocha Mateusz , Medygrał Michał , Buszek Sylwia , Sokołowska Aldona , Rumian Maciej , Kosel Alicja
Published: February 2025

Introduction
Sweeteners are a common sugar alternative, especially in combating obesity and diabetes. With low calorie content, they appeal to health-conscious individuals. The food industry uses natural options like stevia or erythritol and synthetic ones such as aspartame or saccharin. While recognized as safe at recommended doses, debates continue about their long-term effects, emphasizing the need for further research. This paper explores the properties, benefits, and risks of sweeteners.
Aim of the Study
This study examines the effects of sweeteners on human health and evaluates their suitability as sugar substitutes for modern consumers, highlighting their benefits and potential risks.
Materials and Methods
An analysis of PubMed papers was conducted using keywords: sweeteners, artificial sweeteners, erythritol, acesulfame potassium, sucralose, aspartame, and sugar alternatives.
Basic Results
Both natural and synthetic sweeteners are used as sugar substitutes to address concerns about excessive sugar intake. Research indicates they help reduce calorie consumption and control blood sugar levels. However, uncertainties remain about their long-term health effects. Some studies suggest possible changes in metabolism or gut microbiota, but evidence is inconclusive. Regulatory bodies like the FDA deem approved sweeteners safe within recommended daily limits. Despite their advantages, further research is needed to fully understand their long-term impact.
Conclusion
Sweeteners are gaining popularity as sugar alternatives, particularly in the context of obesity and diabetes. Their variety allows for diverse dietary applications. While safe within recommended doses, questions about their long-term effects persist. They aid in weight control and glucose regulation but are not universally suitable. A balanced approach and further research are crucial.
Nutrition and Physical Therapy in the Prevention and Treatment of Endometriosis
Authors: Krzemińska Paulina , Gołębski Maciej , Nowak Wojciech , Mikołajczyk Jagoda , Kukla Zuzanna , Mieruszyńska Stella , Sadowska Izabela , Kołodziej Joanna , Sawicki Mirosław , Włosiański Jakub , Musialik Sebastian
Published: February 2025

Endometriosis is a chronic inflammatory disease which the benign growth of functioning endometrial glands and stroma in ectopic locations, i.e. outside the uterine cavity. In the 60s of the twentieth century, endometriosis had become the main cause of surgery in women. Sick women suffering from this condition often have non-specific symptoms, such as pelvic pain and are often associated with the menstrual cycle. can lead to reduced mental, physical, and social well-being and a lower quality of life. There are many factors that predispose to the onset and course of the disease. Some of them are physical activity and diet. There is a lack of high-quality, robust, randomized studies. However, available studies show that diet and physical activity reduce inflammation that occurs in endometriosis. They have a positive effect on markers of oxidative stress. The purpose of this review is to provide knowledge about the symptoms, effects of nutrition and physical activity in the prevention and treatment of endometriosis.
Unsteady ground: understanding the problem of BPPV in the world of sports
Authors: Nowak Wojciech , Sawicki Mirosław , Mikołajczyk Jagoda , Krzemińska Paulina , Gołębski Maciej , Kukla Zuzanna , Musialik Sebastian , Mieruszyńska Stella , Włosiański Jakub , Sadowska Izabela
Published: February 2025

Introduction: Dizzyness and Vertigo are one of the most common symptoms presented by patients, often the symptoms are caused by BPPV. BPPV may by provoked by certain types of impacts, head motion and other various factors including sport practice. In modern world, sport has become a part of everyday life, both in professional in amateur matter. Different sports, may lead to different types of injuries and related complications, one of them is dizzyness and vertigo. We investigated the existing data about the prevalence of BPPV related to certain types of physical activity. Different sports vary in the movement profile, amount and frequency of impacts. Furthermore, the injuries resulting from physical activity are not always associated with direct hits. Presenting all at once: the data, diagnostic and treatement strategy, we resume the existing knowledge on the phenomenon of BPPV in physical activity.Purpose of work: The article was completed to analyze the available data on the prevalence of BPPV in sports practitioners. This aims to facilitate the prompt resolution of vertigo symptoms in affected individuals and to identify potential, less obvious risk factors that may predispose athletes to this condition.State of Knowledge: Even though the knowledge about the etiology and risk factors of BPPV has significantly advanced in the last decade, more than half of all cases is are still classified as idiopathic. While data on possible new risk factors is growing, it often consists of case reports or orginal studies with small sample sizes, limiting its generalizability. It is widely believed though that certain types of movement may play a role in triggering BPPV.Material and methods: This article is based on a comprehensive review of the literature, conducted using PubMed and Google Scholar. The research focused on studies concerning the prevalence, etiology and risk factors of BPPV, particularly in sports practitioners.
Strength training in pregnancy. Systematic review of benefits and risks
Authors: Demel Karol , Kantor Antoni , Król Jakub , Bialic Łukasz , Dziedzic Monika , Polok Sebastian , Potoczek Adriana , Talaska Justyna , Godyń Marta , Zatłoka-Mazur Dorota
Published: February 2025

BackgroundStrength training during pregnancy has historically been approached with caution, but recent evidence suggests it can be safe and beneficial when properly supervised. This review examines its impact on maternal and fetal health, addressing both advantages and potential risks.
Purpose of ResearchThe study aims to evaluate the benefits and risks of strength training during pregnancy, focusing on maternal and fetal outcomes.
Research Materials and MethodsData were collected from PubMed, MEDLINE, and Web of Science using keywords like "strength training," "pregnancy," and "maternal health." Guidelines from ACOG and RCOG were analyzed to provide evidence-based recommendations.Basic ResultsStrength training, when properly supervised, improves musculoskeletal health, reduces gestational diabetes risk, enhances cardiovascular fitness, and supports mental well-being. It may also promote healthier fetal outcomes by regulating maternal blood sugar levels. Risks include overheating, injury, and strain, particularly in cases of pre-existing conditions or improper exercise execution.ConclusionsIndividualized assessment and tailored programs are essential to maximize benefits and minimize risks. Safe practices, including professional consultation, appropriate exercise selection, and monitoring of intensity, are crucial. Further research is needed to refine guidelines and explore long-term effects. Strength training is a valuable component of prenatal care when conducted safely.
Streaming Submodular Maximization Under Matroid Constraints
Authors: Feldman Moran , Liu Paul , Norouzi-Fard Ashkan , Svensson Ola , Zenklusen Rico
Published: February 2025

Recent progress in (semi-)streaming algorithms for monotone submodular function maximization has led to tight results for a simple cardinality constraint. However, current techniques fail to give a similar understanding for natural generalizations, including matroid constraints. This paper aims at closing this gap. For a single matroid of rank k (i.e., any solution has cardinality at most k), our main results are a single-pass streaming algorithm that uses [Formula: see text] memory and achieves an approximation guarantee of 0.3178 and a multipass streaming algorithm that uses [Formula: see text] memory and achieves an approximation guarantee of [Formula: see text] by taking a constant (depending on ε) number of passes over the stream. This improves on the previously best approximation guarantees of 1/4 and 1/2 for single-pass and multipass streaming algorithms, respectively. In fact, our multipass streaming algorithm is tight in that any algorithm with a better guarantee than 1/2 must make several passes through the stream and any algorithm that beats our guarantee of [Formula: see text] must make linearly many passes (as well as an exponential number of value oracle queries). Moreover, we show how the approach that we use for multipass streaming can be further strengthened if the elements of the stream arrive in uniformly random order, implying an improved result for p-matchoid constraints.

Funding: This research was supported by the Israel Science Foundation [Grants 1357/16 and 459/20] and NCCR—on the Move [Grants 200021_184622 and 200021_184656]. This project also received funding from the European Research Council [Grant 817750] under the European Union’s Horizon 2020 Research and Innovation Programme.
Archivos 2024: Fomentando la conciencia multidimensional en salud laboral
Authors: Vega Álvarez Francisco , Agudelo-Suárez Andrés A. , Brocal Francisco , Delclós Jordi , García González Guillermo , García Vega , Ramada José María , Serra Laura , Vargas-Prada Sergio , Utzet Mireia , Serra Consol
Published: February 2025

La evolución positiva de citas recibidas y otros reconocimientos como la obtención del sello de FECYT o el ascenso a Q3 en SJR, nos permiten afirmar que Archivos de Prevención de Riesgos Laborales se está consolidando como un medio fundamental para la difusión de conocimientos y avances en el campo de la salud laboral, especialmente en el espacio hispanohablante. Su enfoque integral, su adaptación a los retos emergentes y su rigor científico hacen que sea un referente para quienes buscan impulsar la mejora continua de la seguridad y la salud en el trabajo.
The health and wellbeing of NHS staff in a community setting
Authors: Wallbank Sonya
Published: February 2025

Background/Aims

Research relating to the health and wellbeing of NHS staff since the onset of the COVID-19 pandemic has generally focused on those working in acute settings. This study aimed to assess levels of burnout, secondary traumatic stress and compassion satisfaction among staff working for an NHS community care organisation.

Methods

A retrospective, cross-sectional questionnaire was used to assess burnout, secondary traumatic stress and compassion satisfaction (pleasure from delivering a caring role) among NHS staff working for one large community care service. Participants included physicians, nurses and allied health professionals. The Professional Quality of Life scale was used to collect data, with items scored on a 5-point Likert scale. Data were analysed using analysis of variance (ANOVA), producing F scores for each item. Significance was set at P<0.05.

Results

Mean scores for each domain indicated moderate levels of burnout, secondary traumatic stress and compassion satisfaction across sample. All F scores produced using ANOVA were significant at P<0.05. In the burnout and secondary traumatic stress domains, the items with the highest F scores related to feeling worn out, overwhelmed and deeply affected by the trauma experienced by patients whom respondents had helped care for. In the compassion satisfaction domain, the highest F scores related to feelings of satisfaction and pride in one's work.

Conclusions

Healthcare leaders must prioritise time for community staff to cope with and recover from stressful experiences at work. Building compassion satisfaction should also be an area of focus to reduce the risk of stress, burnout and attrition in community care.
Moral injury among military veterans
Authors: Thompson Sam
Published: February 2025

Moral injury can occur when a person has experienced an event that violated their moral or ethical code, and has been frequently observed among military veterans. This article explores the phenomenon of moral injury, its impact on veterans and possible treatments pathways.
Recent Advances in the Diagnosis and Management of Pulmonary Arterial Hypertension
Authors: Mullen Eamon , McCullagh Brian , Gaine Sean , Quadery Syed Rehan
Published: February 2025

Pulmonary arterial hypertension (PAH) is a rare, progressive, debilitating and life shortening condition characterized by raised pulmonary arterial pressures. PAH includes a group of conditions sharing similar pathophysiology, clinical features and response to therapy. The commonest sub-groups of PAH include idiopathic pulmonary arterial hypertension (IPAH), and PAH associated with connective tissue disease. Recently published international guidelines emphasize the need for disease awareness and early referral to expert centres in suspected cases. Following diagnosis and careful risk stratification, combination therapy is recommended using drugs targeting the nitric oxide, endothelin and prostacyclin signaling pathways. Promising new therapies are on the horizon, however, the survival remains disappointing with a median survival of 7 years. In this review, we focus on the diagnostic evaluation, risk stratification, available treatment options and future directions in PAH.
Getting Lean with Protein
Authors: Harding Stephen
Published: February 2025

Advanced material handling equipment supports both taste and quality in industrial protein extraction.
THE IMPACT OF ACHILLES TENDON RUPTURE ON THE STRUCTURE AND FUNCTION OF THE ACHILLES TENDON AND PLANTARFLEXORS AFTER NON-SURGICAL MANAGEMENT: A CROSS-SECTIONAL STUDY
Authors: Briggs-Price Samuel , Yates Tom , Mangwani Jitendra , Bhatia Maneesh , Jones Annette , Silbernagel Karin Gravare , Herbert-Losier Kim , de Vos Robert-Jan , Millar Neal L , Vicenzino Bill , O'Neill Seth
Published: February 2025

Introduction

Acute Achilles Tendon Ruptures (ATR) cause lasting muscular deficits and impair function and quality of life. This study aimed to understand recovery post rupture by examining tendon structure using ultrasound tissue characterisation (UTC), isometric plantarflexor strength, physical activity and patient reported outcomes (PROM).

Methods

Cross-sectional study design consisting of 90 participants. Data were collected from 15 participants at six different rehabilitation timepoints (0, 8, 10 weeks, 4, 6, 12 months). Participants were recruited from a National Health Service clinic using non-surgical management.

Findings

Participants mean (SD) age 48 years (16), 91% male, body mass index 29kg/m2, 54% white British with a median of 1 comorbidity. Primary mechanism of injury was sport (71.1%). Deep vein thrombosis rate was 9.3%.

Based on UTC, ruptured tendon cross-sectional area (CSA) was 287.55 mm2 at 10 weeks, 203.62mm2 at 12 months. Disorganised fibrillar structure was 32% lower at 12 months than 10 weeks. Disorganised fibre percentage was consistent at each assessment point (10 weeks:32%, 12 months:30%).

Isometric plantarflexor strength on the ruptured limb at 12 months was 61.3kg (20.8) or 0.7x body weight (BW) whilst the non-ruptured limb was 93.3kg (29.5) or 1.1x BW. Daily steps increased from 3720 (1889.8) at week 0 to 9048.4 (2750.1) at 12 months.

PROMs at 12 months; ATRS 75.1 (16.5), EQ-5D index .91, EQ-5D VAS 75 (23), SF-36 Physical Functioning 84.3 (9.2), Tampa Scale for Kinesiophobia 34.7 (4.8).

Conclusion

There is substantial remodelling of the tendon during the initial 12 months post ATR, with tendon CSA differing 29% across assessment points. Proportion of disorganised collagen remains consistent from 10 weeks to 12 months post ATR, whilst CSA reduces. Individuals presenting with ATR managed non-surgically have a 34% or 0.4xBW isometric strength deficit at 12 months and still present with fear of movement and reduced function based on PROMs.
DOES THE MEASURE OF ACHILLES TENDON RESTING ANGLE CORRELATE WITH OUTCOME AFTER FUNCTIONAL BRACING AND REHABILITATION FOR ACHILLES RUPTURE?
Authors: Plant Caroline , Skidmore John , Pritchard Andrew , Dhukaram Vivek
Published: February 2025

Background

Acute Achilles tendon ruptures can be a devastating injury with a prolonged recovery period (1). Following the UKSTAR trial, Achilles tendon ruptures are predominately treated with a functional rehabilitation bracing program (2). The aim of treatment is to avoid lengthening of the tendon, and hence the resultant loss of function. The Achilles tendon resting angle (ARTA) provides a simple assessment of tendon length that can be performed in the clinical setting (3). This study assesses the Achilles tendon resting angle over a 52-week period and the correlation with functional outcome.

Methods

A total of 182 consecutive patients with an acute Achilles tendon rupture were treated with a 10-week functional rehabilitation regime. The relative Achilles tendon resting angle was recorded as the difference between the limbs at the time of injury, then once treatment commenced at 4-, 11-, 26- and 52-weeks post injury. Patients with a previous Achilles rupture of the contralateral leg were excluded. The functional outcome was assessed using the Achilles tendon rupture score at 26- and 52-weeks post injury.

Results

The relative Achilles tendon resting angle improved by 5 degrees with functional bracing and plateaued after 11 weeks post injury. The functional outcome continued to improve to 52 weeks post injury with a mean ARTS of 77.9 (15.1). No correlation was detected between the ARTA and ARTS at either 26- or 52- weeks. Only one patient sustained a re-rupture.

Conclusion

Functional bracing reduces the extent of tendon lengthening and improves the functional outcomes of patients up to a year post-injury. The relative ARTA as part of clinical assessment however, fails to provide an indication of the long-term functional outcome of these patients.
MINIMALLY INVASIVE CHEVRON AKIN FOR HALLUX VALGUS SURGERY: A PROSPECTIVE OBSERVATIONAL STUDY WITH MEAN 6.7-YEAR FOLLOW-UP
Authors: Townsend Oliver , Hill Niall , Reaney Adam , Koç Togay , Lewis Thomas , Gordon David
Published: February 2025

Introduction

Minimally invasive (percutaneous) distal first metatarsal osteotomy with internal fixation is an established technique for hallux valgus deformity correction. Published data is limited to 2–3 years follow-up. This study aimed to assess patients undergoing MICA (Minimally Invasive Chevron and Akin) with minimum 5-year follow up, to evaluate the longer-term results of this procedure using validated patient reported outcome measures (PROMs).

Methods

Five-year PROM data was prospectively collected from 117 patients who underwent 169 primary MICA osteotomies between July 2014 and April 2018, performed by a single surgeon. Primary clinical outcome measures included visual analogue scale for pain (VAS-pain), Manchester-Oxford Foot Questionnaire (MOXFQ) and EuroQol-5 Dimensions Index (EQ-5D). Data were collected preoperatively, at 2 years and after a minimum of 5 years. Statistical significance was set at p< 0.05.

Results

169 MICA were performed on 117 patients (112 females, 5 males). Mean follow-up was 6.7 years (standard deviation (SD) 0.96 years). All patients completed minimum 5-year follow-up scores. The MOXFQ scores (mean ± SD) for all 169 feet improved for all domains: from 44.5 ± 22.1 preoperatively to 10.3 ± 17.0 post-operatively for Pain (p<0.001), from 39.2 ± 24.5 to 9.3 ± 17.9 for Walking and Standing (p<0.001) and from 48.2 ± 22.8 to 8.7 ± 17.6 for Social Interaction (p<0.001). VAS-pain improved from 30.8 ± 22.7 to 12.9 ± 21. (p<0.001). EQ-5D Index improved from 0.74 ± 0.14 to 0.90 ± 0.12 (p<0.001).

Conclusion

This is the largest study at this time point presenting PROM data following minimally invasive distal first metatarsal osteotomy. It is also the longest in follow up for this technique. This study demonstrates significant improvement in PROMs at the mid-term and MICA can be considered as an effective and long-lasting option for the management of hallux valgus deformity.
REVISION OF RECURRENT HALLUX VALGUS DEFORMITY USING A PERCUTANEOUS DISTAL TRANSVERSE OSTEOTOMY: SURGICAL CONSIDERATIONS AND MEAN 3.6-YEAR RESULTS
Authors: Lorchan Thomas , Newton Ayla , Ray Robbie , Chua Min Jia , Murphy Evelyn , Lam Peter
Published: February 2025

Background

Hallux Valgus (HV) is a common forefoot deformity that can cause pain and difficulty with walking. There are a range of surgical techniques to treat HV deformity, but there is a risk of recurrence. This paper reviews the clinical assessment and management of recurrent HV as well as a detailed description of how percutaneous surgical techniques can be used to treat recurrent HV. This paper identifies technical challenges of percutaneous HV surgery for recurrent HV deformity as well as strategies to address and mitigate these.

Method

This was a multicenter retrospective review of adult patients who had recurrent hallux valgus deformity (defined as hallux valgus angle>15° and having previously undergone primary surgical intervention for HV deformity correction) who were treated with a percutaneous metatarsal extra-capsular transverse osteotomy (META) technique, with at least one year of follow-up data. Demographic information, hallux valgus angle, intermetatarsal angle, Manchester-Oxford Foot Questionnaire (MOXFQ), visual analog scale (VAS), and EQ-5D-5L scores were collected.

Results

We retrospectively evaluated 34 feet from 32 patients with a mean age of 63.1±9.2 (range 41–82) who underwent revision hallux valgus surgery using a percutaneous technique. The mean follow up was 3.6±2.3 (range 0.5–8.7 years. The breakdown of index HV surgeries was: 17 Chevron, 9 Scarf/Akin, 6 medial bunionectomy, 1 Lapidus, 1 proximal rotation osteotomy. There was a statistically significant improvement in both clinical foot function and radiographic deformity after surgery. The mean HV angle decreased from 32.9±8.6° to 13.4±7.3°, and the intermetatarsal angle decreased from 12.7±3.8° degrees to 3.8±3.1°(p<0.05). The mean MOXFQ Index score significantly improved from 49.4±23.1 to 14.6±19.4 (p<0.05).

Conclusion

This paper suggests that percutaneous surgical techniques using a transverse osteotomy and screw fixation can successfully treat a wide range of recurrent HV deformity severities with significant improvement in clinical and radiographic outcomes.
IS THE DISTAL METATARSAL METAPHYSEAL ANGLE REALLY JUST METATARSAL PRONATION? A WEIGHTBEARING CT ANALYSIS
Authors: Vijapur Arvind , Shaath Mohammed , Patel Shelain , Cullen Nick , Welck Matthew , Malhotra Karan
Published: February 2025

Aims

The distal metatarsal metaphyseal articular angle (DMMA) is a measurement used in the surgical decision making of hallux valgus correction. However, it is difficult to measure on plain radiographs, is subject to projection bias, and its role in pathology is unclear. With the advent of weight-bearing CT (WBCT), our understanding of hallux valgus as a multiplanar deformity has evolved. The aim of this study was to investigate whether there is a relationship between the DMAA and pronation of the first metatarsal head in patients with hallux valgus.

Methods

This was a single-centre, retrospective analysis of 50 patients with hallux valgus deformity who had WBCTs obtained as part of routine pre-operative work-up. Patients with metatarsophalangeal joint arthritis, hindfoot deformity and previous surgery were excluded. From the WBCT images digital radiographs were created and the DMMA measured. Measurements were taken by 2 authors, each repeated twice and the average of all four measurements used in analysis. We also measured intermetatarsal angle (IMA), hallux valgus angle (HVA) and metatarsal pronation angle (MPA).

Results

There were 41 females and 9 males, mean age 52.4±15.8 years. IMA was 14.5±3.3 degrees, HVA was 29.3±8.4 degrees, MPA was 11.7±6.3 degrees, and DMMA was 15.5±5.3 degrees. Intraclass correlation coefficient (ICC) for intra-observer reliability was 0.829 for assessor 1 and 0.910 for assessor 2. ICC for inter-observer reliability was 0.727. Pearsons correlation revealed no link between IMA and DMAA, nor HVA and DMMA. However, there was a significant (albeit small) correlation between MPA and DMMA (r=0.337, p=0.017).

Conclusion

There was reasonable reliability in measuring DMMA between authors on WBCT. Despite this, DMMA appeared to increase with increasing metatarsal pronation. The DMMA may therefore be (in part) projection artefact secondary to metatarsal pronation and surgeons should be aware of this during surgical planning.
La escenificación del conocimiento oficial
Authors: Carranza Isolda E.
Published: February 2025

Dentro de una línea de investigación sobre la construcción discursiva del conocimiento en un contexto institucional, se plantea aquí rastrear los vínculos entre elementos de cooperación y de conflicto que se manifiestan en el nivel concreto de la interacción y condiciones de nivel macro en la sociedad. Los datos provienen de procesos penales y consisten en las interacciones verbales entre testigos y abogados litigantes. Se identifican dos rutinas interaccionales recurrentes como mecanismos de inscripción de lo oficialmente conocido. Se examina la relación entre esta inscripción y la verdad institucional. Además, el análisis de la censura a las desviaciones revela la concepción institucional sobre el conocer. En una rutina, se instaura una puesta en escena para la introducción de contenido como si fuera novedoso en el aquí y ahora. En la otra, se hace prevalecer información que proviene de un hecho de habla en un momento anterior y en otro lugar. La investigación que se reporta logra determinar la función de la escenificación que se logra con las rutinas, su relación con ideales institucionales, y su efecto en el vínculo individuo-colectividad. Por otro lado, se revelan relaciones sociales estratificadas entre diversas categorías de interactuantes que van más allá de los roles situacionales e involucran las posiciones sociales de los participantes.