bluuebunny/crossref_metadata_2025 huggingface dataset:
Biochemical composition of seeds Nigella sativa L., grown in the conditions of Belarus
Authors: Isakova A. L. , Isakov A. V. , Kovalenko N. A. , Feskova E. V. , Supichenko G. N. , Sachivko T. V.
Published: November 2019

It was revealed that the main component of the studied samples composition of the essential oil of Nigella is monoterpene p-cymene, the content of which is ~ 60 %. According to the results of the study of the fatty acid composition of the seed lipids of the studied samples, the prevalence of omega-6 (linoleic) and omega-9 (oleic) unsaturated fatty acids was found (75.11–76.91 % of the total fatty acid content). Samples of NP-13/2 (sum of omega-acids 77.56 %, linoleic acid content – 60.16 %) and NP-4 (sum of omega-acids 77.55 %, oleic acid content – 18.12 %) are promising. In the process of studying the amino acid composition in seed extracts, four essential (leucine, methionine, valine, threonine) and four essential (arginine, proline, serine, glycine) amino acids were identified. A promising sample was NP-13/4 (the sum of amino acids is 62.23 %, the arginine content is 17.56 mg/kg, the leucine is 4.95 mg/kg, and threonine is 4.12 mg/kg). The obtained data testify to the value of using not only ecologically and geographically distant forms, but also samples of hybrid origin of nigella sown, selected and adapted to the conditions of Belarus, as source material in breeding work when creating varieties of medicinal purpose.
Feature of formation of photosynthetic apparatus of microcuttings of Populus tremula L. and Betula pendula Roth. at LED-lighting of various spectral composition during ex vitro adaptation
Authors: Kudelina T. N. , Konstantinov A. V. , Obukhovskaya L. V. , Molchan O. V.
Published: November 2019

The peculiarities of the influence of LED-lighting of different spectral composition with varying ratios of physiologically significant spectral ranges on biometric parameters and the pigment composition of the leaf plate of microclonally propagated aspen (Populus tremula L.) and birch (Betula pendula Roth.) plants were identified during the adaptation ex vitro, which indicate the species specificity of plants response to the illumination spectrum.
Factors determining the composition of the wetland community at renaturalization of the developed peatboards
Authors: Pyshko A. S.
Published: November 2019

The paper presents the results of studies of the number and spatial distribution of 17 species of waterbirds on the territory of the “Dokudovskoye” peat development in the Lida district of the Grodno region. in 2012–2018. Based on the analysis of the dynamics of population indicators and changes in the structure of the habitat, three main factors affecting the bird community of the flooded peatland were identified: hydrological, biotopic, and disturbance factors.
Sozological analysis of the biocomponent Belarusian forestry
Authors: Shabeta M. S.
Published: November 2019

The sociological analysis of the briocomponent of deciduous forests within Belarus is presented in the article. There are 270 species of bryophytes (Bryobionta), 63 of which are liverworts (Marchantiophyta) and 207 mosses (Bryophyta). 94 species are at present to some extent rare or have long been not found, including 13 rare species, and 13 – species in need of preventive protection.
Resident and progenitor stem cells of the heart: morphology and f unction properties and prospects for practical application
Authors: Volotovski I. D.
Published: November 2019

The analysis of literature data on one of the actual problem of modern cell biophysics and biotechnology dealing with mesenchimal stem cells and cordial progenitor cells taking part in reparation of myocardium after its injury and first of all after myocardial infarction was done. Biological properties and potential ability of these cells in reparation processes of myocardium are considered. The recent data on experiments using experimental animals and patients are given. The approaches to increase the efficacy of сell technologies in treatment of injured cardiomyocytes are discussed.
Pengaruh Model Pembelajaran Inkuiri Terbimbing Berbantuan Kit Alat Percobaan Usaha dan Energi terhadap Penguasaan Konsep Fisika Peserta didik
Authors: Pramudyawan Muhammad Tegar Septiaji , Doyan Aris , 'Ardhuha Jannatin
Published: November 2019

Abstract: This research purposed to examine the effect of guided inquiry learning using kit of work and energy experiment tools toward mastery of student physics concepts. This is quasi experiment research with posttest-only control group design. The population of this research is all students of class X MS SMAN 1 Kediri. The sampling technique used is random sampling, so selected the students of class X MS 1 as experiment group and X MS 2 as control group. The experiment group was treated with guided inquiry learning using kit of work and energy experiment tools and the control group was treated with conventional learning. The instrument used to measure concept of mastery is a test instrument in the form of a multiple-choice test of 25 questions. The research hypothesis was tested used t-test at the significance level 5%. The result of t-test showed that there was an effect of guided inquiry learning using kit of work and energy experiment tools toward mastery of student physics concepts. Keywords: Guided inquiry; kit of work and energy experiment tools; mastery of concept
KOMODIFIKASI SENSUALITAS DALAM TAYANGAN KIMI HIME DI MEDIA SOSIAL YOUTUBE
Authors: Gita Liony , Haryono Cosmas Gatot
Published: November 2019

ABSTRACT
This study discusses the discourse contained in the Kimi Hime youtube upload which is quite controversial because it is considered too sensual. This research is a research with a critical paradigm which analyzes the Norman Fairclough critical discourse analysis and uses the content commodification theory proposed by Vincent Mosco. The results of this study indicate that the YouTube show made by Kimi Hime is basically a commodification of sensuality by producing the title and content of the show, including reproducing sensual words and sentences that can arouse male biological desires to attract many viewers and visitors from the social media channel Kimi Hime.
Keywords: Critical Discourse Analysis, Commodification, Sensuality

 

ABSTRAK
Penelitian ini membahas mengenai wacana yang terkandung dalam unggahan youtube Kimi Hime yang cukup kontroversial karena dianggap terlalu sensual. Penelitian ini merupakan penelitian dengan paradigma kritis yang melakukan analisis dengan menggunakan analisis wacana kritis Norman Fairclough dan menggunakan teori komodifikasi konten yang dikemukanan oleh Vincent Mosco. Hasil dari penelitian ini menunjukkan bahwa tayangan youtube yang dibuat Kimi Hime pada dasarnya merupakan suatu komodifikasi terhadap sensualitas yang dilakukan dengan memproduksi judul dan isi tayangan, termasuk di dalamnya mereproduksi kata dan kalimat yang bersifat sensual serta bisa mengguah hasrat biologis lelaki demi menarik banyak penonton dan pengunjung dari kanal media sosial Kimi Hime.
Kata Kunci: Analisis Wacana Kritis, Komodifikasi, Sensualitas
REPRESENTASI NILAI KEMANUSIAAN WEB SERIES KISAH CARLO (Analisis Semiotika dalam perspektif Charles Sanders Peirce)
Authors: Rorong Michael Jibrael
Published: November 2019

ABSTRAK
Simbol, makna dan representasi sangat penting dalam pembentukan makna, setiap aspek yang terkait dengan pembentukan simbol mencerminkan masalah yang begitu kompleks untuk ditafsirkan, kisah carlo adalah seri web yang membentuk aspek transendental dengan ukuran nilai-nilai kemanusiaan, ini tercermin dari setiap adegan yang dilakukan pada setiap cuplikan video dalam cerita carlo ini yang menunjukkan makna dan nilai kemanusiaan melalui tanda dan penanda yang disampaikan. Penelitian ini menggunakan pendekatan penelitian kualitatif dengan teori dan teknik analisis data yang berpijak pada konstruktivis paradiqma dan perspektif Charles Saunder Peirce, untuk melihat tanda-tanda dan penanda dalam menafsirkan realitas sosial yang mencerminkan nilai-nilai kemanusiaan yang ditemukan dalam fenomena serial web yang ditampilkan dalam cerita serial Carlo. makna dan representasi nilai-nilai manusia sebagai level tertinggi dalam level makna dalam seri web cerita carlo.
Kata kunci: Semiotika, Kisah Carlo, Charles Sanders Peirce, Kualitatif, Nilai Kemanusiaan

 

ABSTRACT
Symbols, meanings and representations are very important in the formation of meaning, every aspect related to the formation of a symbol reflects a problem that is so complex to interpret, the story of carlo is a web series that forms a transcendental aspect to the measure of human values, this is reflected from each scene performed on each video footage in this carlo story that shows the meaning and value of humanity through the signs and markers conveyed. This study uses a qualitative research approach with theories and techniques of data analysis that stand on constructivist paradiqma and the perspective of Charles Saunder Peirce, to see signs and markers in interpreting a social reality that reflects human values found in the web serial phenomenon Carlo's story show the meaning and representation of human values as the highest level in the level of meaning in the carlo story web series.
Keywords: Semiotic, Carlo's Story, Charles Sanders Peirce, Qualitative, Value of Humanity
MAKNA SIMBOL TRADISI JHE҃҃҃҃҃҃҃҃҃NG MANTOH (Analisa Semiotika Charles Sanders Peirce
Authors: Suryandari Nikmah , Kurniasari Netty Dyah , J Rose Dian
Published: November 2019

ABSTRACT
This article attempts to explain Charles Sanders Peirce's semiotic analysis of the Jheng mantoh tradition symbol in Madura. The aim of this research is to find out the meaning of the symbols that exist in the Jheng mantoh tradition in Madura which began to be abandoned by the urban Madura community. The jheng mantoh tradition is one of the traditions in Madura, especially the Bangkalan region in the form of a ceremony welcoming the arrival of a daughter-in-law to the bridegroom's family. The purpose of this mantoh jheng is to establish friendship as well as to introduce the bride as a new family member to her husband's extended family. The method in this study is a qualitative descriptive approach to the triadic meaning of Charles Sanders Peirce's semiotics. The results showed that the symbols in the Jheng mantoh tradition in Madura have meanings that are loaded with the noble values of the Madurese community. The stages of Jheng Mantoh tradition are three parts, namely Jheng Mantant pre activity, Jheng Mantoh activity, and post Jheng mantoh. Each stage has its own symbol and meaning. This great jhe҃ng tradition can be found several symbols during the course of this tradition, such as binoculars, sound systems, goat heads, milk fish, tettel, various market snacks, trays, spoons, rituals of tek-tek-tek and so on.
Keywords: jheng mantoh, Madura, semiotic, charles Sanders Peirce

 

ABSTRAK
Artikel ini berusaha menjelaskan tentang analisa semiotika Charles Sanders Peirce pada simbol tradisi Jheng mantoh di Madura. Tujuannya adalah untuk mengetahui makna simbol-simbol yang ada pada tradisi Jheng mantoh di madura yang mulai ditinggalkan oleh masyarakat Madura perkotaan. Tradisi jheng mantoh adalah salah satu tradisi di Madura, khususnya wilayah Bangkalan berupa upacara menyambut kedatangan menantu perempuan di keluarga mempelai laki-laki. Tujuan jheng mantoh ini adalah untuk menjalin silaturahmi sekaligus mengenalkan mempelai perempuan sebagai anggota keluarga baru kepada keluarga besar suaminya. Metode dalam penelitian ini adalah deskritif kualitatif dengan pendekatan segitiga makna semiotika charles Sanders Peirce. Hasil penelitian menunjukkan bahwa simbol-simbol dalam tradisi Jheng mantoh di Madura memiliki makna yang sarat dengan nilai-nilai luhur masyarakat Madura. Tahapan tradisi Jheng mantoh ada tiga bagian, yaitu pra kegiatan jheng mantoh, kegiatan jheng mantoh, dan pasca jheng mantoh. Masing-masing tahapan memiliki simbol dan makna tersendiri. Tradisi jhe҃ng mantoh ini dapat ditemui beberapa simbol selama berlangsungnya tradisi ini, seperti terop, sound system, kepala kambing, ikan bandeng, tettel, aneka jajanan pasar, talam, sendok, ritual tek-tek-tek dan sebagainya.
Kata Kunci: jheng mantoh, Madura, semiotika Charles Sanders Peirce.
TEMPLATE E-COMMERCE
Authors: yuwono ajeng puspaka
Published: November 2019

template e-commerce
Jean Cavailles: life and death. - Georges Canguilhem
Authors: Akmut Camille
Published: November 2019

Trans. Camille Akmut.
19421046
Authors: junaidi
Published: November 2019

ini adalah tugas pemograman java
TEMPLATE ECommerce
Authors: febriyani maria
Published: November 2019

[JUDUL TUGAS]NPM : 17011085NAMA : Maria FebriyaniPRODI : ManajemenFAKULTAS : EkonomiEMAIL : Maria.17011085@student.ubl.ac.idSOAL TUGAS : [1][2][3][4]1. Buat Program website E-Commerce (Topik Apa saja)Buatlah 4 page (website dengan nama sebagai berikut)Page 1 : index.htmlPage 2 : pagedetail1.html (menjelaskan tentang detil produk)Page 3 : pagedetail2.html (menjelaskan tentang detil produk)Page 4 : profilanda.htmlPada page index.html terdapat Menu untuk link ke page (halaman lain) dan dari page lain dapat ke halaman utama (index.html)Setiap halaman memiliki tag yang sudah dipelajariKirim File tersebut :Email : robby.yuliendra@ubl.ac.idSubjek : NPM NAMA UTS SENINFile Name : NPM NAMA UTS SENIN
LAY-UP OPTIMALITY CONDITIONS FOR BUCKLING LEVEL MAXIMIZATION OF VAT (STEERED FIBER) COMPOSITE PLATES
Authors: Selyugin Sergey
Published: November 2019

In the present paper the analysis of the lay-up optimality conditions (derived earlier) for buckling optimization of VAT composite plates is performed. The plates have a symmetric lay-up and loaded along their contour by the in-plane forces. The consideration employs the von Karman approach. The lay-up optimality conditions correspond to the maximization of a single-mode (lowest) buckling eigenvalue. The conditions are comprehensively analyzed. The conclusions of the analysis are presented. The key conclusion is that the optimality conditions with and without account of variation of the in-plane forces are the same.
Dimensional Analysis: Overview and applications to problems of Soil-Structure Interaction
Authors: Garcia-Suarez Joaquin , Kusanovic Danilo S. , Asimaki Domniki
Published: November 2019

Dimensional Analysis is a long-established tool widely used in many branches of engineering and science. However, applications in geotechnical engineering, and in particular soil-structure interaction (SSI), have barely been explored, in spite of the method's potential to clarify parameter influence and shed light on the range of response regimes. The purpose of this text is twofold: (a) it intends to provide a brief introduction to Dimensional Analysis specifically tailored to geotechnical engineers by carefully choosing illustrative examples, (b) it uses Dimensional Analysis to study the parameter space in soil-building interaction problems, emphasizing modeling choices and using a finite-element model to demonstrate the concept of physical similarity. The suitability of using certain dimensionless parameters over others is discussed based on and their magnitude and sensitivity analysis.
HUBUNGAN PENGETAHUAN,SIKAP DAN PRAKTIK PSN DENGAN KEBERADAAN JENTIK NYAMUK
Authors: Mangidi Muhammad Abdul Gafur Tirtayasa
Published: November 2019

Penyakit berbasis lingkungan masih menjadi masalah kesehatan masyarakat hingga kini. Salah satu penyakit yang disebabkan oleh keadaan sanitasi lingkungan yang tidak terkontrol adalah demam berdarah
PERR REIVER Physiological and Genetic Adaptations to Diving in Sea Nomads
Authors: Wibowo Edy
Published: November 2019

PERR REVIWER Physiological and Genetic Adaptations to Diving in Sea Nomads
The Effect of the Post-Socialist Transition on Inequality of Educational Opportunity: Evidence from German Unification
Authors: Betthäuser Bastian Andreas
Published: November 2019

In 1990, German unification led to an abrupt and extensive restructuring of the educational system and economy of the German Democratic Republic (GDR) as the latter was reintegrated into the Federal Republic of Germany (FRG). However, the consequences of this large- scale institutional change for the educational inequality between children from different social class backgrounds in East Germany continue to be poorly understood. This article seeks to shed new light on this question by using a quasi-experimental approach to examine the difference in educational inequality between East and West Germany before and after German unification. We compare changes in the class gradient in educational attainment in East and West Germany across six birth cohorts, including three cohorts of individuals who completed their schooling after unification. Contrasting with past findings, our results show that before unification, educational inequality at the mid-secondary, upper-secondary and tertiary level was substantially lower in East Germany than in West Germany and that unification led to a substantial and sustained convergence of the level of educational inequality in East Germany towards that of West Germany.
Smoking-Attributable Mortality by Cause of Death in the United States: An Indirect Approach
Authors: Lariscy Joseph T.
Published: November 2019

More than 50 years after the U.S. Surgeon General's first report on cigarette smoking and mortality, smoking remains the leading cause of preventable death in the United States. The first report established a causal association between smoking and lung cancer, and subsequent reports expanded the list of smoking-attributable causes of death to include other cancers, cardiovascular diseases, stroke, and respiratory diseases. For a second level of causes of death, the current evidence is suggestive but not sufficient to infer a causal relationship with smoking. This study draws on 1980–2004 U.S. vital statistics data and applies a cause-specific version of the Preston-Glei-Wilmoth indirect method, which uses the association between lung cancer death rates and death rates for other causes of death to estimate the fraction and number of deaths attributable to smoking overall and by cause. Nearly all of the established and additional causes of death are positively associated with lung cancer mortality, suggesting that the additional causes are in fact attributable to smoking. I find 420,284 annual smoking-attributable deaths at ages 50+ for years 2000–2004, 14% of which are due to the additional causes. Results corroborate recent estimates of cause-specific smoking-attributable mortality using prospective cohort data that directly measure smoking status. The U.S. Surgeon General should reevaluate the evidence for the additional causes and consider reclassifying them as causally attributable to smoking.
The Relation of Competency Interpreting Data and Evidence Scientifically and Existential Intelligence
Authors: Setiawan Adib Rifqi
Published: November 2019

The goal of this research is to gain the relation of competency interpreting data and evidence scientifically and existential intelligence. It reveals that they has negative correlation.
The Relation of Scientific Literacy Competencies and Existential Intelligence
Authors: Setiawan Adib Rifqi
Published: November 2019

The goal of this research is to gain the relation of scientific literacy competencies and existential intelligence.
The Relation of Competency Explaining Phenomena Scientifically and Interpersonal Intelligence
Authors: Setiawan Adib Rifqi
Published: November 2019

The goal of this research is to gain the relation of competency explaining phenomena scientifically and interpersonal intelligence. It reveals that they has positive correlation.
The Relation of Competency Evaluating and Designing Scientific Enquiry with Kinesthetic Intelligence
Authors: Setiawan Adib Rifqi
Published: November 2019

The goal of this research is to gain the relation of competency evaluating and designing scientific enquiry with kinesthetic intelligence.
The Relation of Scientific Literacy Competencies and Grade Motivation
Authors: Setiawan Adib Rifqi
Published: November 2019

The goal of this research is to gain the relation of scientific literacy competencies and grade motivation.
The Relation of Competency Interpreting Data and Evidence Scientifically and Interpersonal Intelligence
Authors: Setiawan Adib Rifqi
Published: November 2019

The goal of this research is to gain the relation of competency interpreting data and evidence scientifically and interpersonal intelligence. It reveals that they has positive correlation.
The Relation of Scientific Literacy Competencies and Kinesthetic Intelligence
Authors: Setiawan Adib Rifqi
Published: November 2019

The goal of this research is to gain the relation of scientific literacy competencies and kinesthetic intelligence.
The Relation of Competency Evaluating and Designing Scientific Enquiry with Existential Intelligence
Authors: Setiawan Adib Rifqi
Published: November 2019

The goal of this research is to gain the relation of competency evaluating and designing scientific enquiry with existential intelligence.
The Relation of Scientific Literacy Competencies and Verbal Intelligence
Authors: Setiawan Adib Rifqi
Published: November 2019

The goal of this research is to gain the relation of scientific literacy competencies and verbal intelligence.
The Relation of Competency Explaining Phenomena Scientifically and Verbal Intelligence
Authors: Setiawan Adib Rifqi
Published: November 2019

The goal of this research is to gain the relation of competency explaining phenomena scientifically and Verbal intelligence. It reveals that they has negative correlation.
The Relation of Competency Explaining Phenomena Scientifically and Visual Intelligence
Authors: Setiawan Adib Rifqi
Published: November 2019

The goal of this research is to gain the relation of competency explaining phenomena scientifically and visual intelligence. It reveals that they has positive correlation.
The Relation of Competency Interpreting Data and Evidence Scientifically and Intrapersonal Intelligence
Authors: Setiawan Adib Rifqi
Published: November 2019

The goal of this research is to gain the relation of competency interpreting data and evidence scientifically and intrapersonal intelligence. It reveals that they has positive correlation.
The Relation of Competency Explaining Phenomena Scientifically and Logical Intelligence
Authors: Setiawan Adib Rifqi
Published: November 2019

The goal of this research is to gain the relation of competency explaining phenomena scientifically and logical intelligence. It reveals that they has positive correlation.
The Relation of Competency Explaining Phenomena Scientifically and Naturalistic Intelligence
Authors: Setiawan Adib Rifqi
Published: November 2019

The goal of this research is to gain the relation of competency explaining phenomena scientifically and naturalistic intelligence. It reveals that they has positive correlation.
The Relation of Scientific Literacy Competencies and Intrinsic Motivation
Authors: Setiawan Adib Rifqi
Published: November 2019

The goal of this research is to gain the relation of scientific literacy competencies and intrinsic motivation.
The Relation of Competency Evaluating and Designing Scientific Enquiry with Musical Intelligence
Authors: Setiawan Adib Rifqi
Published: November 2019

The goal of this research is to gain the relation of competency evaluating and designing scientific enquiry with musical intelligence.
Genetic Variability and Heritability of in vitro Chrysanthemum on Various Combination of Plant Growth Regulators
Authors: BDR Muh Farid
Published: November 2019

Heritability is a measure that describes the magnitude of a genetic influence on a character rather than an environmental factor. The higher the heritability value of a character, the higher the genetic variability. The aim of the study was to know the interaction between the combination of growth regulators and chrysanthemum varieties that gave the best chrysanthemum growth in vitro and analyzed the heritability of various chrysanthemum characters. The research was carried out at the In vitro Laboratory of Agronomy Department, Faculty of Agriculture, Hasanuddin University, Makassar from May to September 2016. The study used a separate plot design in the group. The main plot was a combination of growth regulator consisting of 200 ml Coconut Water, 0.5 ppm BAP + Coconut Water 100 ml, BAP 1 ppm + Coconut Water 100 ml, 2,4-D 0.5 ppm + Coconut Water 200 ml, 2,4-D 0.5 ppm + BAP 0.5 ppm + Coconut Water 100 ml, 2,4-D 0.5 ppm + BAP 1 ppm + Coconut Water 100 ml. The subplots included 8 varieties of chrysanthemum (Fiji Pink, Marimar, Pasopati, Salzieta, Solida Pelangi, Limeron, Arosuka Pelangi, Yellow Tumohon). The basic media used was MS medium. The results showed that adding 200 ml young coconut to the culture media gave the best in-vitro chrysanthemum growth in terms of shoot and root formation, shoot count, root number, and shoot height in all chrysanthemum varieties; as well as all observed characters have high heritability and genetic variability
A ‘trace of Stendhal’ in Dostoevsky’s The Adolescent [Podrostok]
Authors: Parsamov V. S.
Published: November 2019

The question of Dostoevsky’s attitude towards Stendhal’s oeuvre remains unanswered. In the absence of direct references, the author suggests searching their works. The novels The Red and the Black and The Adolescent [Podrostok] share in common the issues of a young man’s psychological coming-of-age. Both in their late teens and coming from a peasant background, Julien Sorel and Arkady Dolgoruky are thrown into the alien social milieu of the capital city. Another similarity is the contrast between the immature ideas about life and life as the writer perceives it. In Stendhal’s book, the contrast is depicted as a catastrophic disruption of all social ties, which allows the hero to see the world with new eyes right before his demise. Dostoevsky, on the other hand, shows the process of maturing as a gradual development of new social ties. The comparative analysis of the two novels enables better appreciation of the distinctive character depiction for the two protagonists, and reveals common features that suggest Dostoevsky’s awareness and interpretation of Stendhal’s artistic experiments.
A. Demchenko. N. Chernyshevsky. An academic biography (1828–1858); A. Demchenko. N. Chernyshevsky. An academic biography (1859–1889)
Authors: Gaponenkov A. A.
Published: November 2019

In his review of A. Demchenko’s two-volume academic biography of N. Chernyshevsky, the author dwells on the biographer’s approach to the sources, treated with utmost critical scrutiny. He also discusses the established combination of ideological principles and the evolution of worldview. Chernyshevsky remained a truly democratic thinker throughout his years, and the concept of his democratism is at the core of the biography produced by Demchenko. The book succeeds in creating a multi-faceted perception of Chernyshevsky’s colossal personality, drawing thousands of historical names into its orbit. A. Demchenko meticulously retraces Chernyshevsky’s ‘literary work’: the creative history of What Is to Be Done? [Chto delat?], the works from his Siberian exile, and the lost oeuvre (e. g. the novel The Sower [Seyatel]) as well as Chernyshevsky’s post-Siberian attempt to re-enter big literature and journalism.
Kaganovich, B. (2018). Aleksandr Aleksandrovich Smirnov. 1883-1962. St. Petersburg: Evropeyskiy Dom
Authors: Egorova L. V.
Published: November 2019

With its in-depth knowledge and extensive use of archived and printed material, this book can offer a good learning experience for writers in the same genre: the biography of the Petersburgbased philologist, literary historian, translator, editor, and Professor A. Smirnov (1883–1962) is presented in the context of 20th-c. Russian cultural and literary life. The chapters follow a chronological order and are connected by permeating themes of human and academic relationships: with A. Veselovsky, V. Zhirmunsky, and others. The Shakespearean topic is particularly important in the book: Smirnov personally edited nearly all translations of the Bard’s works appearing in the 1930s–1950s. The biography paints a clear picture of the period and explains why Smirnov never got to write his magnum opus on Shakespeare, despite him having all it took to achieve this, being by nature and training, his philosophy and cultural mentality one of the more consummate ‘Europeans’ among Russian scholars.
Russians in Spain. Book 2. The 20th century. The Beginning
Authors: Pastushkova N. A.
Published: November 2019

Second in the anthology, the volume offers a rich collection of materials, including descriptions of 1900s–1930s Spain by Russian travellers. Artists, musicians, journalists and people of the theatre, all of them share their expectations, recollections and impressions from visits to this Southern country. A poeticized image clashes with reality, which often stands in stark contrast to the idyllic picture. Spain beckons, mesmerizes, and reveals its luxurious self. The country is wrought with controversy: the archaic lifestyle in the provinces and the dizzying pace of life in big cities; its amiable, but very apathetic people; its glorious past and almost desperate present. Russians travel to Spain to experience its natural beauty and splendid cultural heritage. Many of them revelled in visiting the Prado Museum. Numerous performers would come to Spain to tour, spreading knowledge of Russian music, ballet and drama among local audiences.
‘The living word’ of Boris Nepomnyashchy
Authors: Dzutseva N. V.
Published: November 2019

The article paints a literary portrait of the poet B. Nepomnyashchy against the background of Russian Acmeist poetics, defined by its preoccupation with the subject, constant lyrical self-reflection, and the fondness for the genre of a fragment. Particularly important for understanding Nepomnyashchy’s poetry is his connection with I. Annensky: the article centers on their creative dialogue and follows the transformation of Annensky’s reflections of a suffering mind into Nepomnyashchy’s resolute acceptance of fate and clear understanding of one’s poetic vocation. The latter becomes a leitmotif of Nepomnyashchy’s entire work: from his earlier to later poems, he considers his talent as a responsibility, an oracular duty, and faithfulness to God’s truth, hence his exacting approach to himself and his poetry, which he creates with absolute mastery, earning him a place among the most brilliant poets of the 20th c. In her detailed analysis of Nepomnyashchy’s poems in the collection In the Light of the North Star… [Pri svete Polyarnoy…] (1996, 2002), the author recreates a comprehensive idea of his artistic manner as well as the image of the lyrical hero, a resident of the later 20th c.
PRP: Alopecia Areata an Autoimmune Destruction of the Hair
Authors: Garrepally Prasad , Goli Swathi
Published: November 2019

PRP has been used mostly for androgenetic alopecia and alopecia areata since these are the most common types of hair loss. Especially androgenetic alopecia is an extremely prevalent disorder resulting in gradual conversion of terminal hairs into vellus hairs. This is more obvious in men affecting more than 50%, with its well-known hair loss pattern, although there are studies suggesting an almost equal prevalence for women too. A self-renewal of the hair follicle by the keratinocyte stem cells of the bulge have been indicated in androgenetic alopecia, making growth factors signalling a promising future therapy.
Multiple Endocrine Neoplasia Syndrome: Asymptomatic Primary Hyperparathyroidism: A perspective Study
Authors: El-Adl Wael , Serge Kreiter , Suttmann Henrik , Farouk el-Sayed Rania , Attia A M
Published: November 2019

Hyperparathyroidism is a common condition that affects 0.3% of the general population. Primary and tertiary care specialists can encounter patients with primary hyperparathyroidism, and prompt recognition and treatment can greatly reduce morbidity and mortality from this disease. In this paper we will review the basic physiology of calcium homeostasis and then consider genetic associations as well as common etiologies and presentations of primary hyperparathyroidism. We will consider emerging trends in detection and measurement of parathyroid hormone as well as available imaging modalities for the parathyroid glands. Surgical indications and approach will be reviewed as well as medical management of primary hyperparathyroidism with bisphosphonates and calcimimetics.
Is a Biomarker Microvascular Model for Dilation?
Authors: Bian Jing-Tan
Published: November 2019

Does low-fat diet for weight loss make the impaired microvascular dilation improved through switching to nitric oxide (NO)-dependent in obese adults? The answer is yes. Shane Phillips research group has tested this hypothesis through their most recent publication [1]. While systemic NO doesn’t change, localized NO was increased after a six-week low-fat diet for weight loss (~25% calorie deficit) but not for weight maintenance to obsess subjects with body mass index (BMI most subjects in 30-35, and only a few in 35-40 kg/m2) through increasing flow-induced dilation of arterioles. These in vitro microvascular model data are consistent with data with clinical increase of flow-mediated dilation and decrease of BMI in post- compared to pre-low-fat diet for weight loss
HYGIENIC GROUNDS FOR SELECTION CRITERIA FOR PESTICIDE DETECTION IN AGRICULTURAL COMMODITIES, FOOD PRODUCTS AND SOIL (EXAMPLE FOR FUNGICIDES)
Authors: Antonenko A.M. , Vavrinevich O.P. , Omelchuk S.T. , Bardov V.G. , Borisenko A.A.
Published: November 2019

Despite its effectiveness and extensive use, pesticides pose a serious risk to human health. The main way of their penetration into the human body is with food intake. The purpose of this study was to provide hygienic grounds for selecting criteria for pesticide detection in agricultural raw commodities, foodstuffs and soil on the example for fungicide). Materials and methods. The stability parameters of the investigated fungicides in crops typical for soil and climatic conditions of Ukraine have been presented by the results obtained in own field studies. Statistical processing of the results was performed by using the IBM SPSS Statistics Base v.22 Licensed Statistical Suite. Results and Discussion. In order to provide scientific and methodological grounds for national-scale monitoring of fungicide use, the study on dynamics of pesticide content in soil and agricultural commodities and on prediction of the safety of food grown on the soil treated with fungicides of different classes were conducted. According to the hygienic classification of pesticides by their stability in soil and in agricultural commodities, triazoles class compounds have been found out as the most hazardous; the classes of strobilurins, ethylene-bis-dithiocarbamates, cyanopyffoles, anilidopirimidines and anilides have been classified as moderately hazardous, and pyrazolecarboxamides have been assessed as low hazardous. According to the integral hazard index of food contaminated with pesticides, the most of the tested compounds belong to the 3 hazard classes, except for triazoles, strobilurins, and ethylene-bis-dithiocarbamates, which belong to the 2 hazard classes. Conclusion. The following selection criteria have been proposed for monitoring the level of agricultural commodity and food contamination with fungicides: allowable daily dose, hazard class according to toxicity parameters, half-life in agricultural commodities. For soil monitoring, it is recommended to take into account the organic carbon sorption coefficient, allowable daily dose, hazard class according to the parameters of toxicity, half-life in soil, persistence index.
ROLE OF TRANSCRIPTIONAL FACTOR NF-κB IN DEVELOPMENT OF OXIDATIVE STRESS IN HEART OF RATS DURING SYSTEMIC INFLAMMATORY RESPONSE INDUCED BY BACTERIAL LIPOPOLYSACCHARIDE
Authors: Akimov O.Ye. , Vetkina A.Yu. , Malyk A.I. , Shkodina A.D. , Denysenko S.V. , Kostenko V.O.
Published: November 2019

Systemic inflammatory response syndrome (SIRS) is a threatening complication that can lead to myocardial infarction. Activation of the nuclear transcription factor κB (NF-κB) plays an unambiguous role in the SIRS development. The purpose of this study is to determine the effect of NF-κB nuclear transcription factor activation on production of superoxide anion radical (O2•-), superoxide dismutase (SOD) and catalase activity, concentration of free malondialdehyde (MDA) in the heart of rats during SIRS modelling. The experiment was performed on 24 mature Wistar male rats weighing 180-220 g. Animals were divided into 3 groups consisting of 8 animals (control, SIRS group, NF-κB blockade group). SIRS was modelled by intraperitoneal administration of bacterial lipopolysaccharide (Pyrogenal) in a dose of 0.4 μg / kg 3 times a week in the first week; then once a week for 2 months. The blockade of NF-κB was performed by administration of ammonium pyrrolidine dithiocarbamate (PDTC) in a dose of 76 mg / kg. Production of O2•-, activities of SOD and catalase, concentration of MDA was investigated in 10% heart tissues homogenate. Induction of SIRS by Pyrogenal increases basic production of O2•- by 54.6% compared to the control group. Production of O2•- by microsomal electron transport chain (ETC) and NO synthase increases by 52.9%; production of O2•- by mitochondrial ETC increases by 38,9%. Activity of SOD increases by 1.86 times, activity of catalase increases by 1.53 times. The concentration of free MDA in heart tissues has grown by 81.2%. Blockade of the transcription factor NF-κB reduces basic production of O2•- by 38.9%; by microsomal ETC and NO synthase by 41%; by mitochondrial ETC by 22.2% compared to SIRS group. SOD activity decreases by 56.7%, while catalase activity does not statistically significantly change. The concentration of free MDA in heart tissues decreases by 31.4%. Activation of the nuclear transcription factor NF-κB in the heart of rats during SIRS induced by Pyrogenal leads to an increase in O2•- production with subsequent development of oxidative stress. Compensatory activation of antioxidant enzymes under these conditions is not able to prevent the development of oxidative stress in heart tissues.
DYNAMICS OF HEMATOLOGICAL INDICES IN RATS AFTER ADMINISTRATION OF DIAMOND-CARBON COATED STEEL IMPLANTS INTO THE FEMUR
Authors: Makarov V.B. , Morozenko D.V. , Gliebova K. B.
Published: November 2019

Introduction. The pathological body response to metal implants is considered to be well known. There are a lot of studies devoted to this issue. This work is devoted to investigating the dynamic changes of haematological indicators as markers reflecting body response to the insertion of steel implants with diamond-carbon coating in rats. The purpose of the study is to assess the effects caused by steel implant with a diamond-coated coating on rat’s body by assessing hematological parameters. Materials and methods. The study involved 61 male rats: five of which were intact animals, and the rest was divided into two groups (28 animals in each). The first group was the control group, in which rats were inserted non-coated steel implants into the femoral metaphysic; the second group was test group, in which rats were inserted steel diamond-coated implants). The age of animals at the beginning of the experiment was 5–6 months, the body weight was 300–400 g. Blood for research was taken from the animals after decapitation in 7, 14, 30 and 90 days following the implantation. The blood samples were measured for the red blood cell, white blood cells, haemoglobin, leukogram. The findings obtained were processed by statistical analysis methods. Results and conclusions. The first group of the rats with inserted steel implants without coating showed the number of erythrocytes and haemoglobin did not differ from those in the intact rats, the leukocyte count on the 7th and 14th days was reduced by 31.8 % to 39.4 %, respectively; on the 7th day the percentage of lymphocytes and monocytes increased by 13.0 % and 5.0 % due to the toxic immunosuppressive effect of steel implants on the body of the experimental animals. The 2nd group of rats, which were inserted diamond-coated steel implants in their femurs, the rates of erythrocytopoiesis, the leukocyte number and leukogram characteristics remained unchanged during all the observation periods, except for an increase in the percentage of eosinophils on the 7th day and lymphocytes on the 90th day of follow- by 3 % that indicates a less pronounced body response in comparison with the animals of I group.
EFFECTS OF SILVER NANOPARTICLES ON PENTYLENETETRAZOL-INDUCED KINDLED SEIZURES IN RATS
Authors: Pervak M. P.
Published: November 2019

Silver nanoparticles are used for delivering neurotropic agents to brain, increasing the bioavailability of insoluble drugs as well as for brain tumours treatment. Their effects upon brain excitability, especially under conditions of chronic epilepsy modelling are underinvestigated. The purpose of the study was to study the effects of silver nanoparticles upon pentylenetetrazol-induced kindled seizures in rats. Material and Methods. Experiments were performed on Wistar rats kindled during four weeks with pentylenetetrazol administrations in a dose of 30.0 mg/kg, i.p. Only rats, which demonstrated generalized clonic-tonic seizures in a response to each of three last epileptogen injections, were included into the study. Nanoparticles and ionized argentum were administered in a dosage of 0.2 mg/kg, i.p. Observation was performed in early and postponed period of kindling – in 24 h and three weeks from the moment of kindling induction, correspondently. Results and discussion. The calculation of the pentylenetetrazol dose, which effectively induced seizures in 50 % of kindled rats (ED50), was performed in kindled animals in 24 h from the moment of last epileptogen administration was 22.0 mg/kg. In postponed period of kindling (three weeks from the moment of last pentylenetetrazol administration in a dose of 30.0 mg/kg, i.p.), ED50 of pentylenetetrazol was 16.0 mg/kg. ED50 of pentylenetetrazol, which induced clonic seizures in 50 % animals at the early stage of kindling, was recalculated following the administration of ionized and nanoparticle forms of silver, and were less when compared with such ones determined in the control group by 13.5 % (P>0,05) and 26.0 % (P<0,05), respectively. In the postponed period of kindling ED50 of ionized and nanoparticle forms of silver were less when compared with control by 20.0 % (P<0.05) and by 42.0 %, respectively (P<0.05). Significant difference was noted between groups treated with ionized and nanoparticle silver (P<0.05). The net intensification of pentylenetetrazol seizure manifestations was seen in kindled rats treated with silver nanoparticles, when seizure discharges amplitude achieved 1.0-1.2 mV and frequency of 3/sec, which exceeded the ones in rats treated with ionized silver. Conclusion. Silver nanoparticles induce the increase in seizures severity in pentylenetetrazol-kindled rats, and this effect was more pronounced at the postponed stage of kindling development.
PATHOGENESIS OF ENDOTHELIAL DYSFUNCTION IN DIABETIC RETINOPATHY DURING STREPTOZOTOCIN-INDUCED DIABETES MELLITUS
Authors: Sirman Ya. V. , Savytskyi I. V.
Published: November 2019

One of the main diabetes complications that can lead to the disability of patients is diabetic retinopathy. The purpose of the study was to investigate endothelial dysfunction markers in modelled diabetic retinopathy. Material and methods. The experiment was conducted on male rats of the Wistar line, weighing 180-220 grams, up to 3 months of age (inclusive). During the experiment, the animals were divided into two groups. The 1st group included 20 intact animals; the 2nd group had 60 animals with modelled diabetes mellitus and non-proliferative diabetic retinopathy. Results and discussion. Having studied endothelial nitric oxide synthase, we have found out significant differences (p <0.001) when comparing the findings obtained in the 2nd group with the findings of the intact animals. The 2nd group rats were simulated with diabetic retinopathy without following correction. We also observed the decreasing dynamics of this index. For a more detailed study of the functional state of the endothelium and its disruption, we selected the von Willebrand factor, which is one of the common markers showing the damage to the functional state of the endothelium. In the group with simulated pathology, the level of the investigated marker increased compared with intact animals (p <0.001). There was an increase in endothelin-1 level (p <0.001) in the laboratory rats with modelled diabetic retinopathy. Conclusion. The study results have proven that our experimental model of diabetes mellitus and one of its complications, diabetic retinopathy is accompanied by the development of endothelial dysfunction. There has been found as increase in the von Willebrand factor in the modelled pathological process. We have detected an increase in endothelin-1, a marker of vasoconstriction and endothelial dysfunction, 30 days since the beginning of the experiment. Inhibition of endothelial NO synthase activity indicates an impairment of the physiological NO synthesis.
5-YEAR DYNAMICS OF FEATURES OF LEFT VENTRICULAR GEOMETRY IN PATIENTS WITH ISCHEMIC HEART DISEASE, DEPENDING ON TREATMENT TACTICS
Authors: Guta R.R. , Beck N.S. , Radchenko O.M.
Published: November 2019

Introduction. For a patient with coronary heart disease, recovery from myocardial revascularization is a complex process. Cardiac remodeling involves, after myocardial infarction, hypertrophy and dilation, resulting in impaired systolic-diastolic cardiac function, which is an additional risk factor for events. Prospective studies have shown a relationship between left ventricular size and the risk of cardiovascular events. Given this, there was a need to conduct our research. Purpose: To determine the prevalence of types of left ventricular geometry in patients with coronary heart disease, post-infarction cardiosclerosis, depending on therapeutic tactics: revascularization or conservative therapy for 60 months. Material and Methods: We examined 101 patients aged 58.6±4.2 years after myocardial revascularization (n = 71) and with conservative treatment only (n = 30), in whom the dynamics of echocardiographic parameters of the heart were evaluated for 5 years. The values ​​of remodeling myocardial mass index of the left ventricle and the relative thickness of the left ventricle were determined. Results and Discussion. At baseline, patients with concentric left ventricular hypertrophy (50.0%) and concentric remodeling (24.1%) predominated in the main group. Normal geometry in 14.8% and eccentric left ventricular hypertrophy were observed in 11.1%. In the comparison group, eccentric hypertrophy and concentric left ventricular remodeling were most commonly observed, 29.6% each, slightly less than 25.9% concentric hypertrophy, and the least was normal geometry (14.8%). After 60 months, patients with both groups did not experience normal left ventricular geometry and concentric remodeling. The concentric type (80.0%) was predominant in the main group, and the eccentric type (55.6%) in the comparison group. Conclusions. In patients with ischemic heart disease, postinfarction cardiosclerosis progresses in 5 year follow-up myocardial hypertrophy regardless of treatment. After revascularization, concentric left ventricular hypertrophy develops more often, whereas under conservative treatment, left ventricular eccentric hypertrophy is combined with systolic dysfunction and left atrial dilatation. After revascularization, an increase in the index was associated with an increase not only in body weight but also in changes in lipid profile and diastolic hypertension.