bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Acute and Chronic Exercises on Executive Function in Children and Adolescents: A Systemic Review and Meta-Analysis
Authors: Liu Shijie , Yu Qian , Li Zaimin , Cunha Paolo Marcello , Zhang Yanjie , Kong Zhaowei , Lin Wang , Chen Sitong , Cai Yujun
Published: January 2021

Background: Physical exercises can affect executive function both acutely and chronically, with different mechanisms for each moment. Currently, only a few reviews have elaborated on the premise that different types of exercises have different mechanisms for improving executive function. Therefore, the primary purpose of our systematic review was to analyze the effects of acute and chronic exercises on executive function in children and adolescents.

Objective: We identified acute and chronic exercise studies and randomized controlled trials (RCTs) of executive function in children and adolescents that reported overall effect, heterogeneity, and publication bias of acute and chronic exercises on executive function.

Methods: We searched for RCTs of exercise interventions in children and adolescents from databases including PubMed, Web of Science, Scopus, The Cochrane Library, CNKI (China National Knowledge Infrastructure), and Wanfang, from January 1 2009 to December 31 2019. We performed methodological quality evaluations on the included literature using the Physiotherapy Evidence Database Scale (PEDro) and graded evidence with a meta-analysis using Stata 12.0 software.

Results: In total, 36 RCTs were included (14 acute exercises, 22 chronic exercises); the overall results of the meta-analysis (4,577 students) indicated that acute exercises significantly improved working memory (standardized mean difference (SMD) = −0.72; 95% confidence interval (CI) −0.89 to −0.56; p < 0.001), inhibitory control (SMD = −0.25; 95% CI −0.40 to −0.09; p = 0.002), and cognitive flexibility (SMD = −0.34; 95% CI −0.55 to −0.14; p < 0.005), whereas chronic exercises significantly improved working memory (SMD = −0.54; 95% CI −0.74 to −0.33; p < 0.001), inhibitory control (SMD = −0.30; 95% CI −0.38 to −0.22; p < 0.001), and cognitive flexibility (SMD = −0.34, 95 % CI −0.48 to −0.20, p < 0.001).

Conclusion: Acute and chronic exercises can effectively improve the executive function of children and adolescents. The effects on inhibitory control and cognitive flexibility are considered as small effect sizes, while the effects on working memory are considered as moderate effect size. Limited by the quantity and quality of the included studies, the above conclusions need to be verified with more high-quality studies.
Physical and Psychological Impact of the Phase One Lockdown for COVID-19 on Italians
Authors: Tommasi Marco , Toro Francesca , Arnò Simone , Carrieri Angelo , Conte Marco Maria , Devastato Marianna Daria , Picconi Laura , Sergi Maria Rita , Saggino Aristide
Published: January 2021

The exceptional pandemic due to the 2019 coronavirus disease (COVID-19) has obliged all Italians to stay at home. In the literature, there are evidences that traumatic global events, such as natural catastrophes and pandemic, have negative effects on the physical and psychological health of the population. We carried out a survey to analyze the physical and psychological conditions of Italians during the pandemic. Due to the severe limitations in moving during the phase one lockdown, the survey was administered by internet. Results show that Italians followed the provisions established by the Italian government to avoid contamination, but 43% of them declared to have suffered from physical symptoms, in particular migraine, sleep disorders, persistent exhaustion, and difficulty of concentration. They have great fear to be contaminated or that relatives or friends can be contaminated, and they actively take actions to avoid contamination. Participants declared that they had suffered a lot of inconveniences due to restrictions in their movements, and that their life habits were strongly changed. They spent their time at home in different activities, but their psychological well-being was strongly impaired by the lockdown. The level of anxiety tripled, in relation to the prepandemic period, and 30% of males and 41% of females declared to have severe levels of depression. Participants with high levels of optimism and hopefulness show a stronger resilience against anxiety and depression. In addition, there is a negative correlation between anxiety and depression and the five factors of personality. These results show that psychological diseases must not be neglected, and that people in lockdown do need support for their psychological health, also with the help of internet and communication technologies.
Negative Mood States Are Related to the Characteristics of Facial Expression Drawing: A Cross-Sectional Study
Authors: Nanayama Tanaka Chika , Higa Hayato , Ogawa Noriko , Ishido Minenori , Nakamura Tomohiro , Nishiwaki Masato
Published: January 2021

An assessment of mood or emotion is important in developing mental health measures, and facial expressions are strongly related to mood or emotion. This study thus aimed to examine the relationship between levels of negative mood and characteristics of mouth parts when moods are drawn as facial expressions on a common platform. A cross-sectional study of Japanese college freshmen was conducted, and 1,068 valid responses were analyzed. The questionnaire survey consisted of participants’ characteristics, the Profile of Mood States (POMS), and a sheet of facial expression drawing (FACED), and the sheet was digitized and analyzed using an image-analysis software. Based on the total POMS score as an index of negative mood, the participants were divided into four groups: low (L), normal (N), high (H), and very high (VH). Lengths of drawn lines and between both mouth corners were significantly longer, and circularity and roundness were significantly higher in the L group. With increasing levels of negative mood, significant decreasing trends were observed in these lengths. Convex downward and enclosed figures were significantly predominant in the L group, while convex upward figures were significantly predominant and a tendency toward predominance of no drawn mouths or line figures was found in the H and VH groups. Our results suggest that mood states can be significantly related to the size and figure characteristics of drawn mouths of FACED on a non-verbal common platform. That is, these findings mean that subjects with low negative mood may draw a greater and rounder mouth and figures that may be enclosed and downward convex, while subjects with a high negative mood may not draw the line, or if any, may draw the line shorter and upward convex.
Older Adults’ Emotion Recognition Ability Is Unaffected by Stereotype Threat
Authors: Atkinson Lianne , Murray Janice E. , Halberstadt Jamin
Published: January 2021

Eliciting negative stereotypes about ageing commonly results in worse performance on many physical, memory, and cognitive tasks in adults aged over 65. The current studies explored the potential effect of this “stereotype threat” phenomenon on older adults’ emotion recognition, a cognitive ability that has been demonstrated to decline with age. In Study 1, stereotypes about emotion recognition ability across the lifespan were established. In Study 2, these stereotypes were utilised in a stereotype threat manipulation that framed an emotion recognition task as assessing either cognitive ability (stereotypically believed to worsen with age), social ability (believed to be stable across lifespan), or general abilities (control). Participants then completed an emotion recognition task in which they labelled dynamic expressions of negative and positive emotions. Self-reported threat concerns were also measured. Framing an emotion recognition task as assessing cognitive ability significantly heightened older adults’ (but not younger adults’) reports of stereotype threat concerns. Despite this, older adults’ emotion recognition performance was unaffected. Unlike other cognitive abilities, recognising facially expressed emotions may be unaffected by stereotype threat, possibly because emotion recognition is automatic, making it less susceptible to the cognitive load that stereotype threat produces.
Virtual Reality Reward Training for Anhedonia: A Pilot Study
Authors: Chen Kelly , Barnes-Horowitz Nora , Treanor Michael , Sun Michael , Young Katherine S. , Craske Michelle G.
Published: January 2021

Anhedonia is a risk factor for suicide and poor treatment response in depressed individuals. Most evidence-based psychological therapies target symptoms of heightened negative affect (e.g., negative inferential style) instead of deficits in positive affect (e.g., attenuated reward response) and typically show little benefit for anhedonia. Viewing positive scenes through virtual reality (VR) has been shown to increase positive affect and holds great promise for addressing anhedonic symptoms. In this pilot study, six participants with clinically significant depression completed 13 sessions of exposure to positive scenes in a controlled VR environment. Significant decreases were found in self-reported anhedonia, depression, anxiety, and impairments in functioning from baseline to 1-month follow-up. Negative affect decreased over all 13 sessions, and positive affect increased over sessions 8–13. Results suggest that positive experiences in VR may be a novel avenue for the treatment of anhedonia in depressed individuals.
Why People Enter and Embrace Violent Groups
Authors: Gómez Ángel , Martínez Mercedes , Martel Francois Alexi , López-Rodríguez Lucía , Vázquez Alexandra , Chinchilla Juana , Paredes Borja , Hettiarachchi Mal , Hamid Nafees , Swann William B.
Published: January 2021

We distinguish two pathways people may follow when they join violent groups: compliance and internalization. Compliance occurs when individuals are coerced to join by powerful influence agents. Internalization occurs when individuals join due to a perceived convergence between the self and the group. We searched for evidence of each of these pathways in field investigations of former members of two renowned terrorist organizations: the Liberation Tigers of Tamil Eelam (LTTE) (Study 1) and Islamist radical groups (Study 2). Results indicated that ex-fighters joined LTTE for reasons associated with both compliance and internalization but that ex-fighters joined Islamist radical groups primarily for reasons associated with internalization. When compliance occurred, it often took the form of coercion within LTTE but involved charismatic persuasion agents within Islamist groups. This evidence of systematic differences in the reasons why fighters enter violent groups suggests that strategies for preventing radicalization and fostering de-radicalization should be tailored to particular groups.
Emotional Impact of COVID-19 Lockdown Among the Spanish Population
Authors: Gismero-González Elena , Bermejo-Toro Laura , Cagigal Virginia , Roldán Angustias , Martínez-Beltrán María Jesús , Halty Lucía
Published: January 2021

Background

The COVID-19 pandemic has resulted in some populations being confined to their homes as part of infection control measures. This situation can be hard to cope with due to separation from loved ones, prohibition of regular activities, fear of infection, loss of freedom, and so on. These negative impacts cause considerable psychological stress, and all the more so when the situation continues for an extended period, as was the case in Spain. The present study was aimed at investigating the effects of COVID-19 quarantine on the emotional functioning of confined Spanish individuals after 8 weeks of lockdown by means of a cross-sectional study. The possible associations between changes in emotional functioning and demographic variables (age and sex), health habits (physical exercise, following a routine, and smoking), social support, and resilience were also analyzed.

Methods

A total of 906 Spanish adults completed an online survey to gather information about their prevailing mood and affects (before and after 8 weeks of lockdown), using the Positive and Negative Affect Schedule (PANAS) (Watson et al., 1988), and other variables related to their habits and protective factors.

Findings

As expected, the data indicated an increase in negative affects (e.g., “upset,” “afraid,” “distressed”) and a decrease in positive affects after 8 weeks under lockdown, as well as a general decline in overall mood. The largest increases in negative affects were observed in young adults (18–35 years) and women. We did not find any differences between people who were or were not diagnosed with COVID-19. Adhering to a routine, maintaining the same weight, and moderate physical exercise were associated with fewer negative affects, which indicates they are important protective factors, as are perceived social support and resilience.

Conclusion

In order to mitigate the psychological impact of confinement, it is important to develop psychoeducational measures that encourage subjects to adhere to health habits and promote social support and resilience as protective factors. A special preventive focus should be placed on the most vulnerable population groups, namely women and young adults. For a public health lockdown to succeed, its negative consequences must be minimized insofar as possible through adequate knowledge of the risk factors and protective factors, and by means of prevention-oriented organization.
Impact of Adverse Childhood Events on the Psychosocial Functioning of Children Affected by Parental HIV in Rural China
Authors: Ezell Jordan , Harrison Sayward E. , Jiang Yanping , Li Xiaoming
Published: January 2021

Introduction: Children affected by parental HIV are more likely than unaffected peers to experience trauma and are at-risk for negative psychological and social outcomes. This study aimed to examine the relationship between adverse childhood events and psychosocial functioning among children affected by parental HIV.

Methods: A total of 790 children ages 6–17 from Henan, China were enrolled in a longitudinal, randomized controlled trial of a resilience-based psychosocial intervention. At baseline, children reported on numerous psychosocial factors, including trauma exposure, symptoms of anxiety and depression, and peer social functioning. We used linear regression analysis to test the direct effect of trauma exposure on peer social functioning. We then tested whether depression and anxiety symptoms served as two potential parallel mediators in the association between trauma exposure and peer social functioning.

Results: Trauma exposure was significantly associated with poor peer social functioning (β = −0.10, p = 0.005) when controlling for key covariates. When depression and anxiety symptoms were added to the model, the association between trauma exposure and peer social functioning became nonsignificant. Instead, there were significant indirect effects from trauma exposure to peer social functioning via depression (β = −0.06, 95%CI[−0.09, −0.03]) and anxiety (β = −0.02, 95%CI[−0.04, −0.00]).

Conclusion: This study is among the first to link trauma exposure to peer social functioning deficits for children affected by parental HIV and demonstrates that symptoms of anxiety and depression mediate this relationship. Findings underscore the need for comprehensive psychosocial support for children affected by HIV, including screening for trauma exposure and mental health disorders.
A Resilient Health System in Response to Coronavirus Disease 2019: Experiences of Turkey
Authors: Keskinkiliç Bekir , Shaikh Irshad , Tekin Ahmet , Ursu Pavel , Mardinoglu Adil , Mese Emine Alp
Published: January 2021

Turkey's response experience thus far with the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic affords the globe and the region a unique opportunity for and distinctive insights into combating this novel virus. The country's pandemic response, having one of the lowest case fatality ratio (2.8%; 52.5 infections/million population), particularly among the elderly (the high-risk group), rising to the occasion to shoulder its long-standing role in global solidarity and humanitarian support by providing personal protective equipment (globally scarce) to many countries in their desperate time of fight against the pandemic while also meeting its own critical domestic needs, stands out. This paper aims to highlight key decisions, actions, and partnerships behind Turkey's successful fight against the SARS-CoV-2 pandemic that have enabled the country to turn the corner, as well as the components of its success story.
Common European Origin of Hepatitis E Virus in Human Population From Eastern Romania
Authors: Porea Daniela , Anita Adriana , Vata Andrei , Teodor Danut , Crivei Luciana , Raileanu Cristian , Gotu Vasilica , Ratoi Ioana , Cozma Andreea , Anita Dragos , Oslobanu Luanda , Pavio Nicole , Savuta Gheorghe
Published: January 2021

The purpose of this research was to improve the epidemiological data on HEV infection in the human population in Romania. The analysis targeted hospitalized subjects with acute hepatitis (n = 94) of unknown etiology from the Infectious Diseases Regional Hospital in Iasi. Moreover, patients without liver disease (n = 40) from a different county hospital located in Eastern Romania were included. The presence of HEV infection and first characterization of human HEV strains was determined using serological and molecular assays. The apparent HEV seroprevalence varied between 29.16% (95% CI, 16.31–42.03) and 32.5% (95% CI, 17.98–47.02) according to patient grouping. Molecular analysis enhanced the detection of two HEV isolates, that clustered in subtype HEV-3c, the most commonly identified subtype in Europe. Identification of acute hepatitis E cases, together with the first detection and molecular characterization of human HEV in Romania represent the originality attributes of the present study.
Scientific Collaboration at National Institute of the Atlantic Forest (Brazil) on Scopus Database: Analysis of Institutional Domain
Authors: Freitas Juliana Lazzarotto , Rosas Fabio Sampaio
Published: January 2021

Domain analysis by means of scientific collaboration enables evidencing aspects that are involved in the establishment of relationships between researchers and institutions, such as the influence of institutional management models for the development of collaborative networks. This article aims to analyze the domain through the scientific collaboration network of the National Institute of the Atlantic Forest (INMA), a research unit currently affiliated to the Brazilian Ministry of Science, Technology and Innovation (MCTI), formerly known as the Professor Mello Leitão Museum of Biology (MBML), in order to acknowledge the institutional research identity in its historical journey as a public institution. It is thus analyzed how co-authorship constitutes this network and what research profile it reveals. Co-authorship analysis is adopted as a methodology, as well as the analysis of administrative documents with the survey and categorization of employees, regarding their types of ties to the institution, combined with searches in the Scopus database for the corroboration of institutional affiliations. A corpus of 138 articles published by 41 researchers from 1993 to 2019 is consolidated in this base, which represents 44% of the Institute’s total research collaborators (93 collaborators). Of these 41, 92.5% have temporary links, such as scholarship holders and/or volunteers, with the remaining being public workers. It is recognized that the citation impact of the scientific production of scholarship holders, consigned to the Institute, is less than the citation impact of the volunteers' and public workers' production. It is evidenced that eight of the ten publications with the greatest impact and thematic prominence correspond to the field of zoology, with emphasis on the fields of herpetology and primatology. Macro-level collaborative relations are more intense with the United States, in both areas mentioned, covering 16% of the total corpus of articles in cooperation with that country. Zoology, besides its greater impact, accounts for more than half of the corpus production (65.9%).On the other hand, botany is responsible for 30.4% of the corpus, with its dispersed international cooperation in a broad variety of countries. Individual authorship articles are 57% consigned to botany. In summary, the accomplished analysis will contribute to the development of institutional domain analysis methodologies that present scientific collaboration as a basic procedure.
Simulating Beef Cattle Herd Productivity with Varying Cow Liveweight and Fixed Feed Supply
Authors: Farrell Lydia J. , Morris Stephen T. , Kenyon Paul R. , Tozer Peter R.
Published: January 2021

The liveweight of New Zealand beef cows has increased in recent decades due to selection for higher growth rates. Published data suggest that the efficiency of beef cow production decreases with increasing cow liveweight. Changes in beef herd size, feed demand, production, and cash operating surplus (COS) were simulated with average mature cow liveweight varied to 450, 500, 550, and 600 kg. With total annual beef feed demand fixed at the same level, in all scenarios cow numbers and numbers of weaned calves decreased with increasing cow liveweight. When the model was run with consistent efficiency of calf production across the mature cow liveweights (scenario A), heavier cows were more profitable. However, using published efficiency data (scenarios B and C), herds of heavier cows were less profitable. The likely most realistic scenario for New Zealand hill country farms (scenario B) had COS decrease from New Zealand Dollars (NZD) 456/ha with a herd of 450 kg cows to NZD 424/ha with 600 kg cows. Reductions in COS were relatively small, which may not deter farmers from breeding heavier cows for higher calf growth rates. However, the results of this analysis combined with indirect potential economic impacts suggest that the heaviest cows may not be optimal for New Zealand hill country conditions.
Effects of Vermicompost, Compost and Digestate as Commercial Alternative Peat-Based Substrates on Qualitative Parameters of Salvia officinalis
Authors: Greco Carlo , Comparetti Antonio , Fascella Giancarlo , Febo Pierluigi , La Placa Giulia , Saiano Filippo , Mammano Michele Massimo , Orlando Santo , Laudicina Vito Armando
Published: January 2021

Peat is a common substrate used for the cultivation of potted plants. However, the use of peat in horticulture has recently been questioned from an environmental standpoint, since it is a non-renewable resource and plays a major role in atmospheric CO2 sequestration. The aim of this work was to assess the potentialities of substrates obtained from vermicompost, compost and anaerobic digestion processes to partially substitute peat for sage (Salvia officinalis L.) cultivation. Therefore, we planned an experiment to assess the effect of these substrates on essential oil (EO) yield and composition, as well as on leaf nutrients concentration of sage plants. The three substrates were mixed with commercial peat (Radicom) at a ratio of 40% of alternative substrates and 40% of commercial peat. The chemical properties of the alternative substrates did not affect the leaf content of macro and micronutrients, as well as of heavy metals. Moreover, the EO yield and quality was not affected by the substrates and did not differ among them. Results provided evidence that the three alternative substrates can be used to partially substitute peat in soilless cultivation of sage plants. However, due to the higher values of the electrical conductivity of the substrates obtained from composting and anaerobic digestion processes, such substrates must be used with caution.
Llama and Alpaca Management in Germany—Results of an Online Survey among Owners on Farm Structure, Health Problems and Self-Reflection
Authors: Neubert Saskia , von Altrock Alexandra , Wendt Michael , Wagener Matthias Gerhard
Published: January 2021

An online survey of llama and alpaca owners was used to collect data on the population, husbandry, feeding, management measures and health problems. A total of 255 questionnaires were evaluated. In total, 55.1% of the owners had started keeping South American camelids within the last six years. The majority managed small farms with fewer than 15 animals (66.4% of 250 farms). More than half of the participants stated that they kept the camelids as hobby animals (64.3%), although they used them for wool production (55.7%) and/or for breeding (51.8%). Vaccination and deworming were carried out on more than 80% of the farms. The most common diseases occurring on the farms were endo- and ectoparasites. A total of 55.3% of the owners estimated their own knowledge of South American camelids as good, 14.5% as very good. In contrast, more than half of the owners agreed little or not at all with the statement that veterinarians generally have sufficient knowledge about South American camelids. Further research is needed to include veterinarians’ perspectives and thus optimise animal husbandry.
Obstacle Avoidance in a Three-Dimensional Dynamic Environment Based on Fuzzy Dynamic Windows
Authors: Xu Ce , Xu Zhenbang , Xia Mingyi
Published: January 2021

This paper presents a real-time path planning approach for controlling the motion of space-based robots. The algorithm can plan three-dimensional trajectories for agents in a complex environment which includes numerous static and dynamic obstacles, path constraints, and/or performance constraints. This approach is extended based on the dynamic window approach (DWA). As the classic reactive method for obstacle avoidance, DWA uses an optimized function to select the best motion command. The original DWA optimization function consists of three weight terms. Changing the weights of these terms will change the behavior of the algorithm. In this paper, to improve the evaluation ability of the optimization function and the robot’s ability to adapt to the environment, a new optimization function is designed and combined with fuzzy logic to adjust the weights of each parameter of the optimization function. Given that DWA has the defect of local minima, which makes the robot hard to escape U-shaped obstacles, a dual dynamic window method and local goals are adopted in this article to help the robot escape local minima. By comparison, the proposed method is superior to traditional DWA and fuzzy DWA (F_DWA) in terms of computational efficiency, smoothness and security.
Influence of Spanwise Distribution of Impeller Exit Circulation on Optimization Results of Mixed Flow Pump
Authors: Wang Mengcheng , Li Yanjun , Yuan Jianping , Osman Fareed Konadu
Published: January 2021

The spanwise distribution of impeller exit circulation (SDIEC) has an important influence on the performance of the impeller. To quantitatively study the influence of SDIEC on optimization results, a comprehensive optimization system composed of the computational fluid dynamics, inverse design method, design of experiment, surrogate model, and optimization algorithm was used to optimize a mixed flow pump impeller in two different cases. In the first case, the influence of SDIEC was ignored, while in the second case, the influence of SDIEC was considered. The result shows that the optimization upper limit can be further improved when the influence of SDIEC is considered in the optimization process. The pump efficiency of the preferred optimized impeller F1 obtained in the first case at 1.2Qdes, 1.0Qdes, and 0.8Qdes are increased by 6.48%, 2.41%, and 0.06%, respectively, over the baseline model. Moreover, the pump efficiency of the preferred optimized impeller S2 obtained in the second case further increased by 0.76%, 1.24%, and 1.21%, respectively, over impeller F1. Furthermore, the influence of SDIEC on the performance of the mixed flow pump is clarified by a comparative analysis of the internal flow field.
Smart Intravenous Infusion Dosing System
Authors: Oros Dragana , Penčić Marko , Šulc Jovan , Čavić Maja , Stankovski Stevan , Ostojić Gordana , Ivanov Olivera
Published: January 2021

Intravenous (IV) infusion therapy allows the infusion fluid to be inserted directly into the patient’s vein. It is used to place medications directly into the bloodstream or for blood transfusions. The probability that a hospitalized patient will receive some kind of infusion therapy, intravenously, is 60–80%. The paper presents a smart IV infusion dosing system for detection, signaling, and monitoring of liquid in an IV bottle at a remote location. It consists of (i) the sensing and computation layer—a system for detection and signaling of fluid levels in the IV bottle and a system for regulation and closing of infusion flow, (ii) the communication layer—a wireless exchange of information between the hardware part of the system and the client, and (iii) the user layer—monitoring and visualization of IV therapy reception at a remote location in real time. All layers are modular, allowing upgrades of the entire system. The proposed system alerts medical staff to continuous and timely changes of IV bottles, which can have positive effects on increasing the success of IV therapy, especially in oncology patients. The prescribed drip time of IV chemotherapy for the full effect of cytostatics should be imperative.
Convolutional Neural Network in the Evaluation of Myocardial Ischemia from CZT SPECT Myocardial Perfusion Imaging: Comparison to Automated Quantification
Authors: Chen Jui-Jen , Su Ting-Yi , Chen Wei-Shiang , Chang Yen-Hsiang , Lu Henry Horng-Shing
Published: January 2021

This study analyzes CZT SPECT myocardial perfusion images that are collected at Chang Gung Memorial Hospital, Kaohsiung Medical Center in Kaohsiung. This study focuses on the classification of myocardial perfusion images for coronary heart diseases by convolutional neural network techniques. In these gray scale images, heart blood flow distribution contains the most important features. Therefore, data-driven preprocessing is developed to extract the area of interest. After removing the surrounding noise, the three-dimensional convolutional neural network model is utilized to classify whether the patient has coronary heart diseases or not. The prediction accuracy, sensitivity, and specificity are 87.64%, 81.58%, and 92.16%. The prototype system will greatly reduce the time required for physician image interpretation and write reports. It can assist clinical experts in diagnosing coronary heart diseases accurately in practice.
Improvement of Damage Segmentation Based on Pixel-Level Data Balance Using VGG-Unet
Authors: Shi Jiyuan , Dang Ji , Cui Mida , Zuo Rongzhi , Shimizu Kazuhiro , Tsunoda Akira , Suzuki Yasuhiro
Published: January 2021

In this research, 200 corrosion images of steel and 500 crack images of rubber bearing are collected and manually labeled to build the data set. Then the two data sets are respectively adopted to train VGG-Unet models in two methods, aiming to conduct Damage Segmentation by inputting different size of data set. One method is Squashing Segmentation to input squashed images from high resolution directly into VGG-Unet model while Cropping Segmentation uses cropped image with size 224 × 224 as input images. Because the proportion of damage pixels in the data set is different, the results produced by the two data sets are quite different. For large size damage (such as corrosion) segmentation, Cropping Segmentation has a better result while for minor damage (such as crack) segmentation, the result is opposite. The main reason is the gap in the concentration of valid data from the data set. To improve the capability of crack segmentation based on Cropping Segmentation, Background Data Drop Rate (BDDR) is adopted to reduce the quantity of background images to control the proportion of damage pixels from the data set in pixel-level. The ratio of damage pixels from the data set can be decided by different value of BDDR. By testing, the accuracy of Cropping Segmentation becomes relatively higher under BDDR being 0.8.
Self-Powered, Hybrid, Multifunctional Sensor for a Human Biomechanical Monitoring Device
Authors: Lu Yeh Hsin , Lo Hsiao Han , Wang Jie , Lee Tien Hsi , Fuh Yiin Kuen
Published: January 2021

For personal and daily activities, it is highly desirable to collect energy from multiple sources, not only for charging personal electronics but also for charging devices that may in the future sense and transmit information for healthcare and biomedical applications. In particular, hybridization of triboelectric and piezoelectric energy-harvesting generators with lightweight components and relatively simple structures have shown promise in self-powered sensors. Here, we present a self-powered multifunctional sensor (SPMS) based on hybridization with a novel design of a piezoelectrically curved spacer that functions concurrently with a zigzag shaped triboelectric harvester for a human biomechanical monitoring device. The optimized SPMS had an open-circuit voltage (VOC) of 103 V, short-circuit current (ISC) of 302 µA, load of 100 kΩ, and maximum average power output of 38 mW under the operational processes of compression/deformation/touch/release. To maximize the new sensor’s usage as a gait sensor that can detect and monitor human motion characteristics in rehabilitation circumstances, the deep learning long short-term memory (LSTM) model was developed with an accuracy of the personal sequence gait SPMS signal recognition of 81.8%.
Association between ApoE ε4 Carrier Status and Cardiovascular Risk Factors on Mild Cognitive Impairment among Mexican Older Adults
Authors: Aguilar-Navarro Sara G. , Gonzalez-Aparicio Itzel I. , Avila-Funes José Alberto , Juárez-Cedillo Teresa , Tusié-Luna Teresa , Mimenza-Alvarado Alberto Jose
Published: January 2021

Mild cognitive impairment (MCI) (amnestic or non-amnestic) has different clinical and neuropsychological characteristics, and its evolution is heterogeneous. Cardiovascular risk factors (CVRF), such as hypertension, diabetes, or dyslipidemia, and the presence of the Apolipoprotein E ε4 (ApoE ε4) polymorphism have been associated with an increased risk of developing Alzheimer’s disease (AD) and other dementias but the relationship is inconsistent worldwide. We aimed to establish the association between the ApoE ε4 carrier status and CVRF on MCI subtypes (amnestic and non-amnestic) in Mexican older adults. Cross-sectional study including 137 older adults (n = 63 with normal cognition (NC), n = 24 with amnesic, and n = 50 with non-amnesic MCI). Multinomial logistic regression models were performed in order to determine the association between ApoE ε4 polymorphism carrier and CVRF on amnestic and non-amnestic-MCI. ApoE ε4 carrier status was present in 28.8% participants. The models showed that ApoE ε4 carrier status was not associated neither aMCI nor naMCI condition. The interaction term ApoE ε4 × CVRF was not statistically significant for both types of MCI. However, CVRF were associated with both types of MCI and the association remained statistically significant after adjustment by sex, age, and education level. The carrier status of the ApoE genotype does not contribute to this risk.
Hypertensive Crisis in Acute Cerebrovascular Diseases Presenting at the Emergency Department: A Narrative Review
Authors: Cantone Mariagiovanna , Lanza Giuseppe , Puglisi Valentina , Vinciguerra Luisa , Mandelli Jaime , Fisicaro Francesco , Pennisi Manuela , Bella Rita , Ciurleo Rosella , Bramanti Alessia
Published: January 2021

Hypertensive crisis, defined as an increase in systolic blood pressure >179 mmHg or diastolic blood pressure >109 mmHg, typically causes end-organ damage; the brain is an elective and early target, among others. The strong relationship between arterial hypertension and cerebrovascular diseases is supported by extensive evidence, with hypertension being the main modifiable risk factor for both ischemic and hemorrhagic stroke, especially when it is uncontrolled or rapidly increasing. However, despite the large amount of data on the preventive strategies and therapeutic measures that can be adopted, the management of high BP in patients with acute cerebrovascular diseases presenting at the emergency department is still an area of debate. Overall, the outcome of stroke patients with high blood pressure values basically depends on the occurrence of hypertensive emergency or hypertensive urgency, the treatment regimen adopted, the drug dosages and their timing, and certain stroke features. In this narrative review, we provide a timely update on the current treatment, debated issues, and future directions related to hypertensive crisis in patients referred to the emergency department because of an acute cerebrovascular event. This will also focus greater attention on the management of certain stroke-related, time-dependent interventions, such as intravenous thrombolysis and mechanic thrombectomy.
Influence of Ausforming Treatment on Super Elasticity of Cu-Zn-Al Shape Memory Alloy for Seismic Energy Dissipaters
Authors: Ćorić Danko , Žmak Irena
Published: January 2021

In order to develop the application of the more cost-effective copper-based shape memory alloys (SMAs), rather than nickel–titanium as earthquake energy dissipaters, the influence of ausforming-induced plastic deformation on phase transformations, microstructure, super elasticity and mechanical properties of the shape memory alloy Cu-26Zn-4Al was examined. These specific SMA properties were targeted by applying appropriate parameters of the thermomechanical (the so-called ausforming) process: beta-phase homogenization at 800 °C for 20 min, one-step hot rolling at 800 °C and water quenching. The results showed significant microstructural changes, increased mechanical resistance and change in the phase transformation behavior. The SMA treated by ausforming retained the reversible austenitic–martensitic transformation ability, with the appearance of the super-elastic effect up to 6% of strain recovery. Although some strengthening occurred after hot rolling (an increase in true yield strength of 125 MPa was detected), all phase transformation temperatures were decreased. The smallest decrease was detected for the austenite finish temperature (32.8 °C) and the largest for the martensite finish temperature (42.0 °C), allowing both the expansion and the lowering of the temperature range of super elasticity, which is favorable for construction applications. It is concluded that it is possible to achieve an optimal combination of adequate strength and improved transformation behavior of Cu-Zn-Al alloy by applying the ausforming treatment.
Techno-Economic Optimization of CSP Plants with Free-Falling Particle Receivers
Authors: González-Portillo Luis F. , Albrecht Kevin , Ho Clifford K.
Published: January 2021

Particle receivers are one of the candidates for the next generation of CSP plants, whose goal is to reduce the levelized cost of electricity (LCOE) to 0.05 $/kWh. This paper presents a techno-economic analysis to study if a CSP system with free-falling particle receiver can achieve this goal. The plant analyzed integrates two ground-based bins to store the excess energy and a supercritical CO2 cycle to generate electricity. The model used for the analysis presents several upgrades to previous particle systems models in order to increase its fidelity, accuracy, and representativeness of an actual system. The main upgrades are the addition of off-design conditions during the annual simulations in all the components and an improved receiver model validated against CFD simulations. The size of the main components is optimized to obtain the system configuration with minimum LCOE. The results show that particle CSP systems can reduce the LCOE to 0.056 $/kWh if the configuration is composed of 1.61 × 106 m2 of heliostats, a 250 m high tower with a 537 m2 falling particle curtain, and 16 h thermal energy storage.
Cardiac Stimulation in the Third Millennium: Where Do We Head from Here?
Authors: Biffi Mauro , Spadotto Alberto , Piemontese Giuseppe Pio , Toniolo Sebastiano , Bartoli Lorenzo , Sorrentino Sergio , Minguzzi Alessandro , Massaro Giulia , Capobianco Claudio , Statuto Giovanni
Published: January 2021

Over the years, pacemakers have evolved from a life-saving tool to prevent asystole to a device to treat heart rhythm disorders and heart failure, aiming at improving both cardiac function and clinical outcomes. Cardiac stimulation nowadays aims to correct the electrophysiologic roots of mechanical inefficiency in different structural heart diseases. This has led to awareness of the concealed risks of customary cardiac pacing that can inadvertently cause atrioventricular and inter-/intra-ventricular dyssynchrony, and has promoted the development of new pacing modalities and the use of stimulation sites different from the right atrial appendage and the right ventricular apex. The perspective of truly physiologic pacing is the leading concept of the continued research in the past 30 years, which has made cardiac stimulation procedure more sophisticated and challenging. In this article, we analyze the emerging evidence in favor of the available strategies to achieve an individualized physiologic setting in bradycardia pacing.
The Impact of Using Kinesio Tape on Non-Infectious Complications after Impacted Mandibular Third Molar Surgery
Authors: Jaroń Aleksandra , Preuss Olga , Grzywacz Elżbieta , Trybek Grzegorz
Published: January 2021

Non-infectious complications such as post-extraction pain, trismus, and swelling are extremely common after impacted wisdom tooth removal. The aim of the study was to assess the impact of using kinesio tape on the level of the postoperative swelling of soft tissues, trismus, and pain in patients undergoing the surgical extraction of an impacted mandibular third molar. One hundred patients undergoing the surgical extraction of a lower wisdom tooth were randomly divided into two groups: a study group with kinesio taping (KT) (n = 50) and a control group without kinesio taping (NKT) (n = 50). The surgical procedure was performed according to the same repeatable scheme. Kinesio tape was applied immediately after surgery in the KT group. In both groups, measurements of swelling, trismus, and pain were performed before the surgery and on the third and seventh postprocedural days. Kinesio tape had a significant effect on the decrease in facial swelling on the third day after surgery and a decrease in trismus and pain severity levels on the third and seventh days after surgery. The kinesio tape method is non-invasive, continuously active throughout the entire application period, and requires no additional patient appointments. KT application is an effective method for reducing postoperative edema, pain, and trismus after impacted mandibular wisdom teeth surgery.
Widespread Mutations in Voltage-Gated Sodium Channel Gene of Cimex lectularius (Hemiptera: Cimicidae) Populations in Paris
Authors: Akhoundi Mohammad , Chebbah Dahlia , Sereno Denis , Marteau Anthony , Jan Julie , Bruel Christiane , Elissa Nohal , Izri Arezki
Published: January 2021

Bed bugs, Cimex lectularius and C. hemipterus, are common blood-sucking ectoparasites of humans with a large geographical distribution, worldwide. In France, little is known about the status of bed bugs’ infestation and their resistance to insecticides, particularly, pyrethroids. Here, we aimed to find mutations in the kdr gene, known to be involved in resistance to insecticides. We gathered bed bugs from various infested locations, including 17 private houses, 12 HLM building complex, 29 apartments, 2 EHPAD, and 2 immigrants’ residences. A total of 1211 bed bugs were collected and morphologically identified as C. lectularius. Two fragments of the kdr gene, encompassing codons V419L and L925I, were successfully amplified for 156 specimens. We recorded sense mutation in the first amplified fragment (kdr1) in 89 out of 156 (57%) samples, in which in 61 out of 89 (68.5%) sequences, a change of valine (V) into leucine (L) V419L was observed. Within the second fragment (kdr2), a homozygous mutation was recorded in 73 out of 156 (46.7%) specimens at the codon 925. At this position, 43 out of 73 (58.9%) specimens had a sense mutation leading to the replacement of leucine (L) by isoleucine (I). Among 162 mutant sequences analyzed (89 for the kdr1 fragment and 73 for the kdr2 one), we detected single point mutation in 26.6%, while 73.4% presented the mutation in both kdr1 and kdr2 fragments. All modifications recorded in bed bug populations of Paris are described to be involved in the knockdown resistance (kdr) against pyrethroids.
Recruitment and Baseline Characteristics of Participants in the AgeWell.de Study—A Pragmatic Cluster-Randomized Controlled Lifestyle Trial against Cognitive Decline
Authors: Röhr Susanne , Zülke Andrea , Luppa Melanie , Brettschneider Christian , Weißenborn Marina , Kühne Flora , Zöllinger Isabel , Samos Franziska-Antonia Zora , Bauer Alexander , Döhring Juliane , Krebs-Hein Kerstin , Oey Anke , Czock David , Frese Thomas , Gensichen Jochen , Haefeli Walter E. , Hoffmann Wolfgang , Kaduszkiewicz Hanna , König Hans-Helmut , Thyrian Jochen René , Wiese Birgitt , Riedel-Heller Steffi G.
Published: January 2021

Targeting dementia prevention, first trials addressing multiple modifiable risk factors showed promising results in at-risk populations. In Germany, AgeWell.de is the first large-scale initiative investigating the effectiveness of a multi-component lifestyle intervention against cognitive decline. We aimed to investigate the recruitment process and baseline characteristics of the AgeWell.de participants to gain an understanding of the at-risk population and who engages in the intervention. General practitioners across five study sites recruited participants (aged 60–77 years, Cardiovascular Risk Factors, Aging, and Incidence of Dementia/CAIDE dementia risk score ≥ 9). Structured face-to-face interviews were conducted with eligible participants, including neuropsychological assessments. We analyzed group differences between (1) eligible vs. non-eligible participants, (2) participants vs. non-participants, and (3) between intervention groups. Of 1176 eligible participants, 146 (12.5%) dropped out before baseline; the study population was thus 1030 individuals. Non-participants did not differ from participants in key sociodemographic factors and dementia risk. Study participants were M = 69.0 (SD = 4.9) years old, and 52.1% were women. The average Montreal Cognitive Assessment/MoCA score was 24.5 (SD = 3.1), indicating a rather mildly cognitively impaired study population; however, 39.4% scored ≥ 26, thus being cognitively unimpaired. The bandwidth of cognitive states bears the interesting potential for differential trial outcome analyses. However, trial conduction is impacted by the COVID-19 pandemic, requiring adjustments to the study protocol with yet unclear methodological consequences.
Safety Program Elements in the Construction Industry: The Case of Iraq
Authors: Buniya Mohanad Kamil , Othman Idris , Durdyev Serdar , Sunindijo Riza Yosia , Ismail Syuhaida , Kineber Ahmed Farouk
Published: January 2021

The construction industries’ unsafe conditions require increased efforts to improve safety performance to prevent and reduce accident rates. Safety performance in the Iraqi construction industry is notoriously poor. Despite this condition, safety research has so far been neglected. Implementing a safety program is a proven initial step to improve safety. Therefore, the aim of this study is to identify the key elements of a safety program in the Iraqi construction industry. To verify and validate a list of safety program elements identified in the literature review, a mixed method approach was used by using interviews and questionnaire surveys. A final list of 25 elements were then analyzed using exploratory factor analysis. The analysis found that these elements can be grouped into four interrelated dimensions: management commitment and employee involvement, worksite analysis, hazard prevention and control systems, and safety and health training. This study contributes to the body of knowledge on safety in the Iraqi construction sector, a research area which has not been adequately investigated previously. They also help decision-makers focus on key elements that are needed to start improving safety performance in this context.