bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISA PENEMPATAN LIGHTNING ARRESTER SESUDAH CUT OUT UNTUK MENGURANGI GANGGUAN TEGANGAN LEBIH PADA TRAFO KL 0074 DI PT. PLN (Persero) ULP KLUNGKUNG
Authors: Kurnia Yulianto Irwan , Rinas I Wayan , Suartika I Made
Published: February 2023

Where it was recorded that according to BMKG data in 2019 in East Bali there were 15,000-30,000 lightning strikes. This gives the potential for, lightning strike on a 20 kV distribution linewhich is quite high. This connection will cause interference to the feeder if the lightning arresteris placed on the distribution transformer incorrectly. The equepment used to protect equipmentfrom lightning surge distrubances, one of which is a lightning arrester. The lightning arresterused in the KL 0074 substation is in place after the cut out. The Losan medium-voltage aerialfeeder is conncected by an A3CS cable for 8.5 km and an MVTIC cable for a distance of 2.02km which is connected to the KL 0074 substation. The distance between the KL 0074transformer and the lightning arrester is 3.75 meters, so it needs to be examined further to findout whether the protection generated by the lightning arrester is optimal or not. Theeresulttofftheanalysissshowwthatttheelightning arrester with an instalation distance of 0.34 meters from thetransformer is still able to cut the lightning surge, with the resulting splash voltage of 124.977.4Volts but the spark voltage is within the tolerance limit of the 125 kV lightning arrester splashvoltage.,
PERKEMBANGAN INFRASTRUKTUR PENGISIAN BATERAI KENDARAAN LISTRIK DI INDONESIA
Authors: Dharmawan I. P. , Kumara I. N. S. , Budiastra I. N.
Published: February 2023

The development of electric vehicles in Indonesia started after the issuance ofPresidential Decree 55/2019 about battery-based eletric vehicles. The development of electricvehicles must be supported with the charging infrastructure so users do not experienceproblems in charging the vehicles and therefore more people will switch to electric vehicle. Thispaper discusses the current status of charging infrastructure for electric vehicle in Indonesia.Currently, there are several type of vehicle charging facilites consist of 7.000 public electriccharging station or SPLU, 97 public electric vehicle charging station or SPKLU, 9 public electricvehicle battery exchange station or SPBKLU distributed across Sumatra, Java, Bali, NTB,Sulawsi and Kalimantan. In the case of Bali, there are 166 of SPLU, 5 of SPKLU, and there isno SPBKLU yet. The total accumulative energy consumed through the charging stations in Baliis 169.481 kWh. The figure is low due to lack of information about the charging station and thefact that the number of electric vehicles in Bali is still low.
DESAIN SIMULASI UNJUK KERJA KODE SMALL KASAMI PADA KANAL MULTIPATH FADING
Authors: Adi Wiguna Sanjaya I Kadek , Pramaita Nyoman , Oka Widyantara I Made
Published: February 2023

Telecommunication capable of handling interference, fading and no less importantissues regarding the confidentiality of user information is very much needed in the currenttechnological era, to overcome this spread spectrum technology is quite developed in theadvancement of telecommunication technology. In this study, the small kasami code was usedas the spreading code. The purpose of this study is to determine the performance of the smallkasami code with changes in the number of multipath components using multipath fadingchannels. The modulation technique uses digital modulation, namely binary phase shift keying(BPSK) with a small kasami code with a code length of 15 in the spreading and spreadingprocess. Analyzed based on BER (Bit Error Rate) versus EB/No (Energy Bit per Noise). In thesimulation of flat fading performance using 1 multipath component, flat fading serves as an idealreference where the simulation BER should resemble the theoretical BER as simulationvalidation so that it can be used on selective fading channels. Variation of multipathcomponents in frequency selective fading channel produces different BER because there isinterference of multipath signal to the desired signal. The number of multipath components asmany as 11 have the most interference signals resulting in the worst performance. The value ofcross correlation between users has poor performance, where the correlation value of user 1with 2, 3, and 4 is more than 0, this value shows that many signal levels experience interferencebetween users.
PERENCANAAN PENAMBAHAN RELAY DIRECTIONAL EARTH FAULT (DEF) UNTUK GANGGUAN SATU FASA KE TANAH DI SALURAN 150 KV GARDU INDUK NUSA DUA – PESANGGARAN
Authors: Yuni Maheswari G. A. P. , Dyana Arjana I Gede , Indra Partha Cok Gede
Published: February 2023

Disruption of short circuit flow of one ground phase that occurred on the transmissionline 150 kV Nusa Dua-Pesanggaran Substation, causing blackouts to occur in the Nusa DuaSubstation area extending to the surrounding area. The disruption that occurred failed to besecured because the GFR (Ground Fault Relay) relay could not detect the presence of a currentinterference so it failed to work. Assisted relays are needed to secure short circuit flowinterference one phase to help the GFR relay, where the selected relay is the DEF (DirectionalEarth Fault) relay. Installation of auxiliary relays requires planning and relay setting steps toobtain Iset, TMS and trip time. Calculations that have been done get the results of the GFR relayworking at a minimum interference of 1,200A while the DEF relay works at a minimuminterference of 0.521A. The one-phase disruption detected on the 150 kV channel based on thesimulation is below 300A. Def relay will work after the GFR relay does not manage to detectinterference of one phase of the land with a time span of 0 - 0.3 seconds.
Morir por defenderte
Authors: Estupiñán del Castillo Carlos Julio , Páez Arenas Sergio Mauricio , Parada Contreras Javier Antonio , Medina López Lorenzo Antonio , Rueda Vásquez Carlos Arturo , Padilla Cepeda Juan Manuel , López Guerrero Germán
Published: February 2023

Esta obra pretende visibilizar y dignificar las historias de vida de 22 soldados de la patria que entregaron su vida por la defensa de todos los colombianos, así como resaltar a los 15 uniformados que sufrieron heridas físicas producto de su compromiso con la patria. Al rendir un homenaje a los integrantes del curso de oficiales Centenario del Himno Nacional a través de los relatos de sus familiares y amigos, a quienes indudablemente se brinda un agradecimiento sincero por su colaboración, se busca evitar que su legado quede en el olvi­do y que su sacrificio sea en vano.
Karakteristik Pasien Keratosis Seboroik Lanjut Usia di Poliklinik Kulit dan Kelamin RSUP Dr. M. Djamil Padang
Authors: Hamzany Tisa , Gustia Rina , Ilahi Fitratul
Published: February 2023

Latar Belakang: Keratosis seboroik merupakan salah satu tumor jinak kulit terbanyak yang dilaporkan pada kelompok umur lanjut. Usia, sinar matahari, genetik dan pekerjan berperan penting dalam faktor risiko peningkatan proses terbentuknya lesi keratosis seboroik. Tujuan penelitian ini adalah untuk mengetahui gambaran karakteristik pasien keratosis seboroik lanjut usia di RSUP Dr. M. Djamil Padang.

Objektif:  Penelitian ini bertujuan untuk mengetahui gambaran karakteristik pasien keratosis seboroik lanjut usia di RSUP Dr. M. Djamil Padang.

Metode: Penelitian ini merupakan penelitian deskriptif observasional dengan desain cross sectional dengan total sampel yaitu 20 sampel pasien lanjut usia yang didiagnosis keratosis seboroik. Penelitian dilakukan di RSUP Dr. M. Djamil Padang pada periode Januari 2019 – Desember 2021.

Hasil: Penelitian ini menunjukkan kelompok usia terbanyak pada rentang usia 60-70 tahun (60%), pekerjaan pasien keratosis seboroik lanjut usia ditemukan lebih banyak di luar ruangan (60%) dengan lama paparan sinar matahari sebesar >6 jam/hari (45%). Gejala subjektif sebesar 55% berupa gatal lebih banyak ditemukan. Wajah adalah lokasi tersering ditemukannya lesi keratosis seboroik pada lanjut usia (51,4%). Durasi sebelum terapi pasien keratosis seboroik lanjut usia sebagian besar >15 tahun (65%) dan untuk pilihan terapi terbanyak adalah elektrokauterisasi (45,2%).

Kesimpulan: Kesimpulan penelitian ini adalah sebagian besar kasus keratosis seboroik lanjut usia di poliklinik RSUP Dr. M. Djamil Padang berumur 60 – 70 tahun, bekerja di luar ruangan, di bawah sinar matahari selama >6 jam/hari, merasakan gatal, ditemukan di wajah, menderita >15 tahun dan mendapatkan terapi elektrokauter.
ALIMENTAÇÃO FORA DO LAR: ANÁLISE DO AMBIENTE ALIMENTAR DE SHOPPING CENTERS DE CAMPO GRANDE, MATO GROSSO DO SUL, BRASIL
Authors: Tavares Giovanna de Moraes Ribeiro , Cippel Gabriela Vaz , Bresan Deise , Sanches Priscila Milene Angelo , Del Ré Patricia Vieira
Published: February 2023

Objetivo: Caracterizar o ambiente alimentar dos shopping centersde Campo Grande/MS, tendo em vista, a relevância de analisar os produtos que estão disponíveis a este público bem como sua qualidade nutricional. Método: Foram avaliados 124 Unidades de Produção de Refeições (UPR) nos shopping centers, por observação direta do cardápio, bufê ou fachada. Para coleta de dados foi utilizado o instrumento NutritionEnvironmentMeasuresSurveyRestaurants (NEMS-R). As variáveis coletadas a partir do referido instrumento foram tipos de unidades, sistema de gestão, serviços de mesa, tipos de alimentos e bebidas disponíveis, facilitadores e barreiras ao consumo de alimentos saudáveis. Resultados: Foram encontrados 29,0% de restaurantes àla carte; 8,1% de restaurantes tipo autosserviço; 36,3% de lanchonetes e 26,6% dos demais (bares, sorveterias, carrinhos/quiosques). Em relação aos tipos de gestão 77,4% são franquias. Entre os alimentos mais comercializados destaca-se as bebidas açucaradas, acessível em 79,8% das unidades e doces/sobremesas em 50,0%. Grande parte das unidades avaliadas não apresenta facilitadores para a alimentação saudável, sendo que mais de 90,0% das unidades não ofereceram opções de porções reduzidas, trocas saudáveis e opções saudáveis para crianças.  A maior barreira encontrada foi a oferta de porções maiores por um pequeno acréscimo de preço (63,7%). Conclusão: O ambiente alimentar encontrado pode dificultar o acesso aos alimentos saudáveis. Assim, sugere-se que políticas públicas de segurança alimentar e nutricional, sejam implementadas, de forma a promover o maior acesso aos alimentos saudáveis que contribuem para a melhoria da qualidade de vida da população.
TECNOLOGIAS PARA PREVENÇÃO DE ACIDENTES DOMÉSTICOS EM CRIANÇAS NA PRIMEIRA INFÂNCIA: REVISÃO DE ESCOPO
Authors: De Sousa Caroline Ribeiro , Fernandes Maria Jéssica da Silva , Do Nascimento Jamile Domingos , Vitoriano Anna Beatriz Pinheiro , Silva Natália de Sousa , Silva Vitória Ferreira
Published: February 2023

A primeira infância é o período que compreende os primeiros seis anos de vida de uma criança. Nesse período ocorre grande parte do seu desenvolvimento físico, psicológico e cognitivo. Objetivo deste estudo foi mapear na literatura as tecnologias utilizadas para prevenção de acidentes domésticos em crianças na primeira infância. Para tal, realizou-se uma revisão de escopo seguindo as diretrizes do PRISMA. Para tanto, os descritores foram “accident home”, “child preschool”, “accident prevention” e “technology” e descritor não controlado: “toodler”. foram consultadas nos bancos de dados de periódicos da PUBMED, SCOPUS, CINAHL, SCIELO, LILACS. Foram incluídos os estudos publicados a partir do ano de 2009 a 2020. Entre os 439 estudos encontrados, 68 artigos eram duplicados, e 361 não atendiam plenamente ao objetivo desta revisão; assim, 10 estudos foram submetidos à apreciação desse escopo. Dentre as tecnologias, a mais utilizadas, foi a tecnologia da informação. Também se utilizou tecnologia impressas do tipo folder, questionários, gamificação, vídeo educativo, dramatização e arteterapia. Os profissionais da saúde têm uma grande responsabilidade na prevenção dos acidentes, pois, os cuidadores depositam muita confiabilidade nestes, que facilitam através de recursos a mudança de comportamentos de risco.
OVERDOSE DE ACESSO À JUSTIÇA? UMA ANÁLISE EXPLORATÓRIO-DESCRITIVA DAS DECISÕES DOS JUÍZES DE DIREITO DAS VARAS CÍVEIS DA COMARCA DE RECIFE (PE) QUANTO AO DEFERIMENTO DOS BENEFÍCIOS DE JUSTIÇA GRATUITA
Authors: Filho Alexandre de Paula , Romão João Luiz Mendes , Neto José Mário Wanderley Gomes
Published: February 2023

Entre as medidas institucionais previstas na legislação brasileira para o enfrentamento do obstáculo econômico ao acesso à justiça está a possibilidade de concessão judicial do benefício da gratuidade da justiça, que permite ao beneficiário litigar livremente em juízo sem a preocupação quanto ao eventual pagamento de custas processuais, honorários advocatícios e demais despesas do processo. Este benefício é objeto de críticas quanto ao alto grau de subjetividade dos critérios normativos para o deferimento da medida, que, em tese, seria capaz de empoderar ainda mais os magistrados de primeiro grau, em razão da ausência de constrangimentos institucionais efetivos. Esse nível de liberdade decisória acarretaria em um deferimento demasiado? Esta pesquisa coletou dados originais sobre processos tramitando nos juízos de direito das varas cíveis da comarca do Recife em que houve pedido de concessão do referido benefício para, através de análise exploratória-descritiva, verificar o respectivo comportamento judicial nestas situações e testar a hipótese acima apresentada.
Avaliação do perfil oxidativo na rinite alérgica relacionada à classificação clínica: estudo transversal
Authors: Faria Alex Pinheiro Simiqueli de , Moreira Tiago Ricardo , Oliveira Leandro Licursi de , Cardoso Silvia Almeida
Published: February 2023

Objetivo: Analisar o perfil oxidativo de pacientes portadores de Rinite Alérgica Persistente, relacionando a sua classificação clínica (leve ou moderada-severa). Métodos: Trata-se de um estudo do tipo transversal, com coleta de dados entre 09/2021 e 02/2022. Após a estratificação clínica de pacientes previamente diagnosticados foi realizada uma coleta de sangue para determinação dos parâmetros hematológicos e bem como para avaliação espectrofotométrica dos marcadores relacionados ao perfil oxidativo. Resultados: Os dois grupos avaliados apresentaram predomínio do sexo feminino, média etária de aproximadamente 30 anos e relataram fazer uso de automedicação. Não foi observado diferença significativa na capacidade antioxidante total entre os grupos avaliados, entretanto os níveis de atividade da enzima antioxidante Catalase se apresentaram significativamente reduzidos no grupo com rinite moderada-severa (91,2 + 90,5 vs. 148,5 + 111,3 μm/L; p=0,048), interessantemente observamos correlação positiva entre os níveis de catalase com proteínas carboniladas (r=0,437 e p=0,0253) e de catalase com índice de massa corporal (r=0,4109 e p=0,037) apenas neste grupo. Conclusão: Nossos dados demonstram que os pacientes com quadros mais graves de rinite alérgica apresentam maiores alterações dos marcadores oxidativos, que se correlacionam positivamente com fatores de risco de agravo do referido quadro.
Estimation of Active Components in Gokshura Tablet and Pushyanug Churna Formulation using High-performance Thin Layer Chromatography Method
Authors: Rathore Priyanka . , Daniel Kratika . , Daniel Vivek . , Singh Charanjeet . , . Yashwant . , Gupta Anil K.
Published: February 2023

Gokshura tablet is an ayurvedic formulation with gokhru (Tribulus terrestris) as best fixing recommended for building vitality levels. It enhances life, sexual want and drive. Pushyanug churna is an ayurvedic polyherbal formulation, hence this seems essential to explain the material institutionalization, various bioactive markers, blends exhibit in the polyherbal ayurveda compositions such as pushyanug churna. Point of the exhibit effort has been to create what’s more, approve a high-performance thin layer chromatography (HPTLC) strategy for assurance of diosgenin present in gokshura tablet. Mangiferin and chlorogenic acid are present in pushyanug churna. Diosgenin, a biomarker chemical found in gokshura tablets, and mangiferin, a biomarker compound found in pushyanug churna, were standardized using recently developed easy and accurate HPTLC procedures. Pre-coated silica gel 60-F254 was employed at the stationary phase and a mixture of toluene, ethyl acetate, and formic acid (in the proportions 5:4:1) was employed for the mobile phase in the development methodology for diosgenin. In the mobile phase, mangiferin, ethyl acetate and methanol were added in a ratio of 40:60 v/v were utilized. In the chlorogenic acid mobile phase, ethyl acetate:formic acid:acetic acid:water (10:1.1:1.1:2.6 v/v). It was determined that the Rf value of the marker chemical was 0.77 (diosgenin) in gokhsura tablet and 0.23 mangiferin, 0.75 chlorogenic acid in pushyanug churna. For bioactive marker chemicals found in in-house and commercially available formulations, the developed HPTLC approach has shown to be straightforward, sensitive, specific, and dependable.
Clinical and Stability Assessment of Chloral Hydrate Syrup for Sedation in Pediatrics
Authors: Omar Elhamdaoui . , Yacine Errouissi . , Karim Souly . , Yahya Bensouda . , Yassir El Alaoui
Published: February 2023

To develop a stable chloral hydrate (CH) syrup and to test its clinical efficacy in inducing painless sedation during diagnostic imaging examinations in children under 4 years of age. For the physico-chemical tests, the vials were stored at + 5 and + 25°C and the analysis was carried out for 60 days. The microbiological tests were performed in 4 days of analysis. The prospective clinical study was conducted in 33 infants and children after receiving CH syrup orally for sedation prior to magnetic resonance imaging (MRI). After two months of storage, the average concentrations in all tests were greater than 95% of the initial chloral hydrate concentration. No microbiological growth was noted after 60 days of storage. The clinical use of syrup in children resulted in effective sedation in 100% of children and rare side effects. Compared to midazolam, chloral hydrate is more effective for sedating children under 5 years of age and is significantly less expensive. The prescription of 5% CH syrup for sedation prior to imaging diagnosis has well-established efficacy. However, the safe use of chloral hydrate in infants and children under 5 years of age should be in accordance with international recommendations.
Preparation and Evaluation of the Effectiveness of Mouthwash Prepared from Few Types of Plant Extracts against Some Types of Pathogenic Bacteria Isolated from Mouth
Authors: Khudhair Zainab H. , Al-Niaame Asmaa E.
Published: February 2023

Problems associated with drug resistance and the toxicity of some medicinal compounds currently in use are a major problem that requires searching for new compounds to overcome these problems. In the current study, two types of mouthwash were prepared, the first representing the mixture of aqueous extracts of Melissa officinalis L., Pimpinella anisum L. and Silybum marianum L. plants and the second represented the mixture of their methanolic extracts. The inhibitory activity of the two prepared types of mouthwash was tested in comparison with the effectiveness of commercial products available in the Iraqi markets, namely oral B and alpha zac against some types of pathogenic bacteria isolated from the mouth of patients attending to some specialized dental centers in the city of Baghdad, where three of them were negative for gram stain represented by (Enterobacter cloacae ssp dissolvens, Kluyvera intermedia and Serratia marcescen). The four gram-positive represented by Enterococcus faecium, Streptococcus mutans, Streptococcus parasanguinis and Staphylococcus aureus, using the diffusion agar method and tube method to determine the minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC). The methanolic and aqueous extracts showed inhibitory activity against most types of bacteria included in this study, as the inhibitory values ranged between 10 to 24 mm. The aqueous’s lowest inhibitory dilution (MIC) was 28% at a concentration of 6.25 μg/mL, and the lowest bactericidal dilution (MBC) was 14% at a concentration of 12.5 μg/mL. These results are close to the inhibitory properties of the methanolic extract, as no significant differences were observed in both MIC and MBC values between both lotions. The prepared aqueous and methanolic extracts lotion showed distinctive stability in terms of pH, density, color, smell and homogeneity over a period of three months from the date of preparation under different storage conditions.
Understanding Degradation Pathway of Poorly Stable Diltiazem Hydrochloride and Development of its Stabilized Controlled-release Tablets
Authors: Agrawal Rajesh . , Mishra Prasad G. , Bansal Balkrishan .
Published: February 2023

Diltiazem hydrochloride is a class -1 drug, as per the breast-conserving surgery (BCS) classification system, which is highly soluble and highly permeable. It is a poorly stable drug that poses many problems during formulation preparation. The stability of the final product is quite challenging. The API undergoes hydrolysis to form desacetyl-diltiazem. It is the major degradation impurity. Desacetyl-diltiazem exhibits only a quarter to half of the pharmacological activity as compared to diltiazem HCl. A correct understanding of the degradation pathway and usage of suitable excipients can provide a stable product with improved shelf life. During the course of various trials and application of factorial designing, an optimized composition for oral controlled release tablets of diltiazem HCl has arrived, suggesting that exposure to an aqueous medium for tablets granulation and eliminating the polyvinylpyrrolidone from the composition significantly improved the product stability and final tablets shelf life by not only maintaining the desired in-vitro drug release profile but also keeping the related substances (impurities level) at very low levels throughout the entire shelf life.
Formulation and Evaluation of the Fenofibrate Spray-dried Emulsion Tablets
Authors: Aarti Nikam , Ravindra Kamble
Published: February 2023

The present research work deals with the development of a self-micro emulsifying drug delivery system (SMEDDS) of Fenofibrate (FF) followed by spray drying to form solid SMEDDS and tablets with enhanced solubility and dissolution. FF is BCS class II drug with low bioavailability and low aqueous solubility. The solubility of the FF can be improved by formulating SMEDDS. Liquid SMEDDS were developed by adding the drug in oleic acid, Tween 80, and Transcutol HP to get a clear solution. In the spray drying method, dextran was used to form the granules. Further, direct compression method was used to manufacture the tablets. The spray-dried product containing solid SMEDDS of FF showed nearly 30-fold solubility enhancement in distilled water in comparison to pure FF. The optimized formulation containing solid SMEDDS of FF (F9) showed an increased dissolution rate (100% drug release at 60 minutes) in comparison to conventional tablets. The optimized batch showed excellent stability at the accelerated condition for the period of 3 months. The current research work demonstrates spray drying as a potential approach to transfer the liquid SMEDSS to a solid SMEDDS with an enhanced solubility and dissolution rate.
Novel Potentiometric Sensor for Estimation of the Moxifloxacin in the Pharmaceutical Samples, Urine, and Serum
Authors: Abrahem Sarra A. , Ahmad Shyama M. , Al-Phalahy Bashaer A.
Published: February 2023

An easy, simple and ecofriendly process for the estimation of moxifloxacin (MFN) in the pharmaceutical samples, serum and blood. The prepared sensors contained moxifloxacin–bromophenol blue as ionphore and, tris(2-ethylhexyl) phosphate, di-butyl phthalate and di-butyl phosphate as plasticizers. The electrodes based on di-n-butyl phthalate (DBPH), Tris (2-ethylhexyl) phosphate (TEHP), and di-butyl phosphate (DBP), gave slope 44.50, 56.86 and 46.38 mV/decade, respectively. The linear concentrations were 1×10-5 - 1×10-2, 5×10-5- 1×10-2 and 5×10-5 - 1×10-2 M with detection limits of 9.0×10-6, 4.7×10-5 and 4.9×10-5 M and a lifetime of 17, 39 and 12 days for electrodes based on DBPH, TEHP, and DBP, respectively. The best electrode was TEHP which gave the best results. The sensor that based on TEHP as plasticizer was better response and stability, it was used to estimate the moxifloxacin in pharmaceutical samples using single and multi-standard addition potentiometry.
The Effect of L-carnitine on Apoptotic Markers (Annexin V and Clusterin) in Polycystic Ovarian Syndrome Women undergoing ICSI
Authors: Alhussien Zahra A. , Mossa Hayder A. L. , Abood Muayad S.
Published: February 2023

Background: Despite abnormal apoptosis of granulosa cells is believed to have a role in the pathophysiology of polycystic ovarian syndrome (PCOS), the cellular and molecular processes behind this are unknown. Atresia occurs in developing PCOS follicles, likely facilitated by increased androgen levels. Atretic follicles are eliminated in the absence of tissue injury or inflammation, suggesting that programmed cell death may be the mechanism behind this process. Aim of the Study: The current study evaluated the protective effect of L-carnitine (LC) against programmed cell death and, eventually, endometrial receptivity. Patients and Methods: This prospective case-control research was performed at the Al-Nahrain University’s high institute for infertility diagnosis and assisted reproductive technologies and the Al-Farah Specialist Fertility Center. Sixty women diagnosed with the polycystic ovarian syndrome were recruited in this research and began their IVF/ICSI cycle; clusterin and annexin V were measured as apoptotic markers in the early follicular phase of the cycle CD2-in the serum and in the follicular fluid on the day of ova pickup. Endometrial thickness was assessed by ultrasound examination.Results: Both serum annexin V and clusterin were decreased significantly after treatment (p< 0.05). The mean endometrial thickness in all enrolled women was 5.30 ± 0.70 mm. There was no significant difference in mean endometrial thickness between the study and placebo groups, 5.43 ± 0.63 versus 5.37 ± 0.66 mm, respectively (p = 0.441). There was no significant difference in mean serum annexin V (p = 0.101), but follicular fluid annexin V and serum and follicular fluid clusterin were lower in the study group than in the placebo group in a significant manner (p
The Role of Vitamin B12 on Adenosine Monophosphate-activated Protein Kinase in Anemic Patients
Authors: Raoof Israa B. , Abdalah Mayssaa E. , Mohsin Raghad A.
Published: February 2023

Background: Anemia affects people at all stage of their lives, but it is most common in pregnant women and young children. Iron deficiencies are metabolic stress since it affects both the abilities to provide oxygen to tissue and the abilities to use oxygen (mitochondrial capability impairment). Vit.B12 plays role in the metabolism of AMP-activated protein kinase which considers as protection against inflammation in-vitro and in-vivo.
Methodology: This study includes 30 samples of the patient and 30 samples as control groups, by centrifugation, blood samples were separated and stored at minus twenty centigrade. Different questions were asked of all patients and control groups. like duration of anemia, malabsorption, malnutrition, history, drugs, weight, height, and smoking
Results: The results showed that the mean value of height levels in patients (162.2 ± 4.495 ) no significant difference (p-value = 0.6) as compared to control groups (165.6 ± 5.359) also in weight levels showed no significant difference (p-value = 0.9) between control (69.3 ± 3.418) and patients groups (63.8 ± 4.654). In vit.B12 levels, the mean value of patients (295.923 ± 162.241) showed a significant difference (p-value = 0.012*) as compared with mean of control groups (482.2 ± 158.12). In transferrin levels, there was a significant difference (p-value=0.04**) in vit.B12 levels between mean of patients (29.307 ± 11.604) and mean of control groups (42.4 ± 8.711). In addition to that, the mean value of Hb levels in patients (9.7 ± 2.200) showed significant difference (p-value = 0.03*) as compared to control groups (14.1 ± 0.94), finally, PCV levels showed a significant difference (P-value = 0.02*) in Polycythemia Vera (PCV) levels between mean of patients (43.3 ± 3.82) and mean of control groups (30.1 ± 6.601).
Conclusion: In this study, further demonstrate that vit.B12 plays role to decrease inflammations by macrophage inhibition; we identify the mechanism of AMP pathway mediate vit.B12 action of anti-inflammations, and reported the relation between vit. B12 and AMP-activated protein kinase (AMPK) phosphorylation, therefore vit.B12 is considered as a novel action of anti-inflammatory reagent responses.
Identification of Flavonoids in Artemisia annua L. by High-performance Liquid Chromatography and Evaluate the Antioxidant Activity
Authors: Mawlood Mawlood K. , Dawood Ali A. , Abdul-Razzaq Noor E.
Published: February 2023

The study aimed to isolate and identify flavonoids in the Artemisia plant, results obtained from the high-performance liquid chromatography (HPLC) analysis indicated that Artemisia plant contains different concentrations of flavonoids, which include 0.995 μg/g (0.58%) artemisinic acid, 3.96 μg/g (2.33%) artemisitene, 10.36 μg/g (6.09%) dihydroartemisinin, 152.25 μg/g (89.6%) artemisinin and 2.318 μg/g (1.36%) deoxyartemisinin. The identification of all types of flavonoids in flavonoids isolated from Artemisia indicates the efficiency of the method for isolating flavonoids from Artemisia, as well as evaluation of flavonoid concentration in Artemisia extract and isolated flavonoids by measurement of the antioxidant effect) in three methods.
The use of Bacterial Cellulose Produced from the Local Isolate Komagataeibacter xylinus TELE8 as an Antibacterial for Wounds
Authors: Al-Deresawi Tayseer S. , Mohammed Melad K. , Khudhair Saad H.
Published: February 2023

The present study aimed to use the bacterial cellulose pre-produced from local isolate Komagataeibacter xylinus TELE8 as antimicrobial dressings for wounds and compared their activity with specific artificial antibacterial. First, the toxicity of bacterial cellulose was examined in-vitro and in-vivo toward the shape and growth of human lymphocytes and then toward skin irritation, respectively. The results showed that there was no effect of bacterial cellulose dressings on the shape and numbers of human lymphocytes compared to the studied positive and negative control samples, also, the results of the study of the effect of bacterial cellulose dressings on the skin surface characteristics indicated that there was no erythema, edema, redness and dryness on the surfaces of the skin exposed to bacterial cellulose in test animals. Thereafter, the effect of BC, anti, and BC + anti dressings were studied using 12 male rabbit of 6 months old and were randomLy distributed into four groups included: a control group (without treatment), BC group (treated with bacterial cellulose), BC + anti group (treated with bacterial cellulose and sodium fusidate), and anti group (treated with sodium fusidate), all wounds in animals were treated for 15 days according to their group and the observations were recorded. The results showed clear and rapid wound healing in two groups, including the BC group and BC +Anti group compared with the anti-group and control group, also, the scores of skin irritation in the two previous groups were significantly lower than the anti-group and the control group for all days of the experiment; therefore bacterial cellulose may provide a promising effect in enhancing wound healing and preventing wound infections that act in delaying wound recovery.
The DNA Extraction from Chlorella Algae, and its Preparation for Real Time-polymerase Chain Reaction
Authors: Abdulameer Sara H , Thabit Hadeel M
Published: February 2023

Our current research involved the extraction of DNA from chlorella algae for prepare it to real-time polymerase chain reaction (RT-PCR) After the collection of algal samples from the riverine quarter environment, they were placed in test tubes, about (1-mL) and centrifuged at (3500 rotation for 5 minutes), with placed a control negative sample for certain the success of the practical steps sequentially of the experiment, and to know the effectiveness of the lytic enzymes, and the reagents which used. When the microalgae are visible down each test tube by watching its green color, 400 μL of the lytic solution add to the remaining sample with mixing, and 10 μL of an enzyme proteinases K are added to them, which helps to break down the walls and membranes of the cells. The incubated of samples at a temperature of 65°C for 1-hour, followed by the addition 400 μL of chloroform phenol (it plays the role of breaking down DNA-related proteins) with shaking, and the samples are centrifuged again to take the upper layer as it represents the DNA of the algal samples, they are withdrawn and transferred to a new pentroph. A 5 μL RNA-ase enzyme is added to them to destroy the RNA and preserve the DNA. Added (500 mL of isopropanol), with mixing well by hand, and centrifuged at 12,000 rotation, for 10 minutes, alcohol removed and DNA extracted prepared for the PCR reaction.
Synthesis of New Tetrazole and Azitidenen Compounds with Evaluating of its Antibacterial Effects
Authors: M Mays Neamah , Jassim Ibtissam K
Published: February 2023

4-((4-chlorobenzoyl)oxy) benzoic acid was used to synthesize new thiazole heterocycles. The antimicrobial, anti-inflammatory, and analgesic activities of the synthesized compounds Schiff base. Then we derive from Schiff base 4-oxoazetidine and 4-oxothiazolidin heterocycles.
Effects of fiber cross-section shape on thermal comfort properties of polyester interlock fabrics
Authors: Marmarali Arzu
Published: February 2023

In this study, some dimensional and thermal comfort properties, i.e. thermal resistance, water vapor permeability, and air permeability properties of interlock fabrics knitted from different cross-section shaped polyester fibers were investigated. Four polyester yarns of different fiber cross-section shapes (hollow-round, round, triangular, and W-shape) were used to produce the samples. From the results, it was found that the triangular and W-type fibers had higher fabric density values due to the denser and closer fiber settlement. The highest bursting strength value belonged to the sample knitted from hollow-round yarn, which had also the highest yarn-breaking load value. The samples knitted from both round cross-section polyester yarns had significantly higher air permeability and thermal resistance values than the other samples due to the lower fabric density values of these fabrics. On the other hand, the water vapor permeability values of the fabrics from triangular and W-type fibers were slightly higher than the others because of their lower thicknesses.
Understanding the Fate of the Banert Cascade of Propargylic Azides. Sigmatropic versus Prototropic Pathway
Authors: Villareal-Parra Miguel , Di Gresia Gabriel E. , Labadie Guillermo R. , VALLEJOS Margarita M.
Published: February 2023

The Banert cascade is an efficient synthetic strategy for obtaining 4,5-disubstituted 1,2,3-triazoles. The reaction can proceed via a sigmatropic or prototropic mechanism depending on the substrate and the conditions. In this work, the mechanism of both pathways from propargylic azides with different electronic features were investigated using DFT, QTAIM and NBO approaches. The calculated energies barriers were consistent with the experimental data. Three patterns of electron density distribution on the transition structures were observed, which reflected the behaviours of the reactants in the Banert cascade. The stronger conjugative effects were associated with lower/higher free activation energies of sigmatropic/prototropic reactions, respectively. A clear relationship between the accumulation of the charge at the C3 atom of propargylic azides with the energy barriers for prototropic reactions was found. Thus, the obtained results would allow the prediction of the reactions course evaluating reactants.
The functions of heraldic symbols in the English fiction
Authors: Moiseiuk Iuliia
Published: February 2023

The article considers the main functions performed by heraldic symbols due to their verbalization in blazons as descriptions of coats of arms by a specific set of language constructs. Heraldic symbols as the quintessence of culture are analyzed in the communicative-functional aspect. There are some special characteristics of heraldic symbolic units, namely, their multifunctional orientation, the possibility of multiple interpretations, the presence of a nomination mechanism, and others. The mediative and mnemonic functions of symbols, taken from the works of Lotman, are manifested in the heraldic symbols of fiction as one of the mechanisms of cultural memory, therefore, the symbol is a mediator of the semiosis spheres. The list of functions is supplemented by the consideration of the social dimension, because heraldic symbols are potentiated in the society, therefore, the essence of the identification-integrative and adaptive-regulatory functions of heraldic symbolism is revealed. The concepts of multimodal imagery and synesthesia effect, which are embodied in the interaction of verbal and nonverbal symbols, are involved in the analysis of the blazons on the material of English fiction. The theme of symbols functioning is supplemented by the classification of the main functions and subfunctions proposed by the author. The focus of the study is also the identification function, resulting in an emphasis on the role of a special heraldic language in the expression of the personality. Taking into account the types of coats of arms, the article considers the coding function in the punning and allusive coats of arms, as well as in the heraldic lexemes borrowed from other languages. The cross-cutting idea of the article is revealed through the interpretation of heraldic symbols in their functioning in the works of English fiction and poetry and summarized in the definition of the symbol not only as a linguistic unit, but also as a semiotic phenomenon of culture.
Achados tomográficos dos pacientes com Pancreatite Aguda no Hospital Universitário da Universidade Federal do Piauí
Authors: Silva Renata Mendes da , Martins Eduardo Bruno Lobato , Araújo Junior Raimundo José Cunha
Published: February 2023

INTRODUÇÃO: A pancreatite aguda é uma das doenças mais comuns do trato gastrointestinal. Para avaliação da gravidade da doença pelos métodos de imagem, os mais difundidos são os critérios tomográficos de Balthazar e a classificação de Atlanta revisada. OBJETIVOS: Avaliar a frequência dos achados tomográficos em pacientes internados com pancreatite aguda no Hospital Universitário da Universidade Federal do Piauí (HU-UFPI), de acordo com as principais classificações radiológicas, comparar com os resultados obtidos na literatura e propor modelo de laudo estruturado para os futuros laudos tomográficos. METODOLOGIA: Estudo observacional, descritivo, retrospectivo, que analisou dados clínicos e demográficos e as imagens tomográficas de pacientes com pancreatite aguda internados no HU-UFPI no período de janeiro de 2015 a dezembro de 2016. RESULTADOS: Foram avaliados 33 pacientes com pancreatite aguda neste período, com idade média de 48,75 anos, sendo 51,5% do sexo masculino. A litíase biliar foi a etiologia em 55% dos casos. A maioria dos pacientes apresentou pancreatite grave de acordo com as classificações radiológicas. Segundo os termos da classificação de Atlanta revisada, os achados tomográficos mais comuns foram a coleção necrótica aguda e o acúmulo líquido peripancreático. Os achados extrapancreáticos mais encontrados foram o derrame pleural e a ascite. Em 58% dos casos houve algum tipo de procedimento ou intervenção cirúrgica, sendo os mais realizados a colecistectomia, a drenagem percutânea e a laparatomia exploradora. CONCLUSÃO: Os achados tomográficos de pancreatite aguda mais comuns foram semelhantes aos encontrados na literatura e foi proposto modelo de laudo estruturado para os relatórios tomográficos.
ANAIS DO IX CONGRESSO DAS LIGAS ACADÊMICAS DA UNIVERSIDADE FEDERAL DO PIAUÍ (COLAC)/ VI CONGRESSO NORDESTINO DE LIGAS ACADÊMICAS DE MEDICINA (COLENE)
Authors: Alves de Oliveira Evaristo Thalia
Published: February 2023

IX Congresso das Ligas Acadêmicas da Universidade Federal do Piauí (COLAC)Dias: 17 a 20 de novembro de 2022.Realização: Universidade Federal do Piauí (UFPI)Local: Campus Ministro Petrônio Portela, Ininga, Teresina-PI.

O IX COLAC - Congresso das Ligas Acadêmicas da UFPI e VIII - CongressoNordestino das Ligas Acadêmicas do Nordeste foi cuidadosamente elaboradovisando a socialização e a troca de experiências entre os participantes, com o objetivode incentivar atividades em pesquisa, buscando complementar a formação dosparticipantes.

Agradecemos a todos que possibilitaram a ocorrência do evento
Epidemiological analysis of COVID-19 cases in city in the South of Ceará
Authors: Fernandes da Silva Mariany , Moreira Maciel Jessyca , Duarte de Sales Janayle Kéllen , Monteiro Rodrigues Lívia , Silva Santos Sheron Maria , Gomes Rocha Cavalcante Edilma
Published: February 2023

Objetivo: Analisar indicadores epidemiológicos acerca dos casos da COVID-19 e o efeito dos decretos instituídos em um município da região sul do Ceará. Métodos: levantamento epidemiológico e descritivo, estruturado a partir de dados secundários relativos à COVID-19, notificados à Secretaria Municipal de Saúde de Caririaçu, Ceará, no período de maio de 2020 a abril de 2021. Foram analisados os registros de notificação, como também os decretos municipais relacionados à COVID-19. Resultados: identificou-se que no período estabelecido o município de Caririaçu notificou 2.974 casos suspeitos de COVID-19. Destes, 32,25% (n=959) foram confirmados e 66,01% (n=1.963) foram descartados. Dos casos confirmados, 46,40% (n=911) foram recuperados, sendo registrado um total de 3,02% (n=29) óbitos pela doença. Nesse mesmo período foram publicados 19 decretos em alusão ao enfrentamento da COVID-19. Conclusão: foi possível observar um crescente número de casos confirmados, mesmo com a prorrogação dos decretos, refletindo a necessidade de realizar avaliação constante das estratégias de prevenção, enfrentamento e controle da doença.
Health, work and presence of cardiovascular risk factors in professors at a public university
Authors: Cruz Neto João , Ramos Natana Morais , Vieira Natália Rodrigues , Lisboa Kenya Waléria de Siqueira Coelho , Gomes Emiliana Bezerra , Oliveira Célida Juliana de
Published: February 2023

Objetivo: identificar a presença dos principais fatores de risco para doenças cardiovasculares em docentes de uma universidade pública. Método: Estudo transversal e de natureza quantitativa com docentes de uma Instituição de Ensino Superior a partir da avaliação e classificação de variáveis clínicas e sociodemográficas registradas pela aplicação de formulário estruturado e interpretadas segundo nível de significância (p<0,05) após apreciação no Statistical Package for the Social Sciences versão 20.0. A coleta realizou-se de agosto de 2016 a julho de 2018. Resultados: Participaram 261 docentes. O IMC obteve resultados significativos quando associado à faixa etária de 34 a 44 anos (p=0,005), sexo masculino (p=0,050) e alteração na circunferência abdominal feminina (p=0,015), PA (p=0,0038), colesterol (p=0,052) e triglicerídeos (p=0,040) em algum momento da vida. Conclusão: Os fatores de risco cardiovascular apresentaram significativa relevância no público estudado e denota que o sexo, alterações do IMC, sedentarismo, dislipidemias, hipertensão e fatores estressores estão associados às doenças cardiovasculares.
A Manifestation of Impression Management in Corporate Reporting in Jse Top 40 Listed Companies
Authors: Phesa Masibulele , Sibanda Mabutho
Published: February 2023

Purpose: The purpose of the study is to exposes impression management in the developing country, with a specific focus on the Top 40 Johannesburg Stock Exchange (JSE). Despite not being required by the International Financial Reporting Standards, the Chairperson's statement is the most read statement among the more than 80% of listed companies. The study investigated profitable and unprofitable companies' use of impression management through passive voice and personal references.

Methodology: Secondary data in form of annual reports were used and self-attribution theory was used as framework. Mixed content analysis was used. Using a targeted sample, the study differentiated between 20 profitable and 20 unprofitable companies, based on the change in pre-tax profit between fiscal 2019 and fiscal 2020.

Findings: Profitable and unprofitable companies used self-attribution bias. The Mann-Whitney test finds no significant difference despite profitable organizations’ using more self-attribution than unprofitable companies. The continued use of impression management deceives investors and impairs their ability to make informed decisions

Implications: The study sends a strong warning to potential investors on use of impression management by listed companies. Further, the study further adds to the debate on impression management through self-attribution in corporate reporting.
Aprender historia a través del juego de realidad virtual inmersiva “Carthago Nova”. Propuesta de integración de un serious game en el proceso de enseñanza-aprendizaje
Authors: Laura Arias Ferrer Laura , Egea Vivancos Alejandro , García López Alfonso
Published: February 2023

Las posibilidades educativas que ofrece la realidad virtual inmersiva (RVI) son actualmente incuestionables, si bien aún se cuenta con escasas propuestas que estén diseñadas expresamente por y para el aula. En esta contribución se presentan los primeros pasos de una interesante iniciativa diseñada por la Fundación Integra (Región de Murcia) entre las que se encuentra el desarrollo de un videojuego de RVI de temática histórica ambientado en el Teatro Romano de Cartagena y al que se juega con gafas Oculus Rift o HTC VIVE. El videojuego ha sido diseñado a modo de serious game y se completa con una secuencia didáctica que permite su integración en el aula. A pesar de que aún no se ha realizado la fase de evaluación de los aprendizajes, la observación de los primeros prepilotajes del juego con estudiantes parecen mostrar su valor como elemento para el aprendizaje y favorecer un acercamiento motivador a la historia.
Didáctica de las Ciencias Sociales a través de los videojuegos: Investigación y experimentación del juego Assassin’s Creed Origins, para posible propuesta didáctica sobre la enseñanza del patrimonio y la cultura del Antiguo Egipto
Authors: Quintero Mora Domingo Luis
Published: February 2023

Muchos investigadores han atribuido a los videojuegos un enorme potencial al uso de éstos en procesos de enseñanza-aprendizaje. Este artículo pretende analizar mediante la experimentación del videojuego «Assassin’s Creed Origins», si es apto para su uso como recurso didáctico en la enseñanza, incluyendo aspectos procedimentales y actitudinales relacionados con las Ciencias Sociales; y más concretamente para la enseñanza y aprendizaje de los diferentes campos o apartados sociales, tales como la economía, la sociedad, la gestión, división o reconocimiento del territorio egipcio. A modo de resumen, nos plantearemos si el videojuego es capaz de transmitir o se reconocen en él, elementos fundamentales de la cultura del antiguo Egipto y en especial de su patrimonio, cuyo legado ha llegado hasta nuestros días.