bluuebunny/crossref_metadata_2025 huggingface dataset:
Suplementación con ensilaje de frutas en vacas doble propósito: digestibilidad y producción láctea
Authors: Castañeda Serrano Román David , Gonzáles Bermeo José Flaminio , Velez Giraldo Alejandra María
Published: July 2023

En condiciones del trópico colombiano es necesario establecer estrategias de alimentación  que permitan aumentar la productividad a bajo costo. El objetivo de esta investigación fue evaluar el efecto de la suplementación con ensilados de totumo, mango, guayabo de monte sobre la digestibilidad in vitro, degradabilidad y parámetros productivos en vacas doble propósito. El estudio realizado en una finca ubicada, municipio de Puerto Boyacá, se usaron 32 vacas (Gyr x Holstein), distribuidas en cuatro (4) grupos de ocho (8) cada uno, conformados de la siguiente manera: T1: grupo control: sin ensilajes; T2: ensilaje de Guayabo de monte; T3: ensilaje de Totumo y T4: ensilaje de Mango común.  Todas las vacas permanecían en pastoreo rotacional con Brachiaria decumbens, agua a voluntad y sal mineralizada. No hubo diferencias (P<0,05) en la producción diaria de leche entre los tratamientos evaluados, sin embargo, el porcentaje de proteína en leche fue mayor (p<0,05) en los tratamientos T2 y T4. EL NUL fue mayor en el T2 y menor en el T4. El consumo de ensilajes fue mayor (p<0,05) en el T4 y la condición corporal mostro ser mejor para los tratamientos T2 y T4, finalmente para los parámetros de degradabilidad y digestibilidad in vitro, los tratamientos T2, T3 y T4 obtuvieron los mayores valores respectivamente. La suplementación de vacas doble propósito con ensilajes de frutos del bosque húmedo tropical mejora la proteína de la leche y la condición corporal de las vacas. Los ensilados estudiados, poseen alta tasa de degradación y digestibilidad In vitro, representando una alternativa de alimentación en los rumiantes.
Efecto del ácido 1-naftalenacético sobre algunos componentes de rendimiento en yuca (Manihot esculenta Crantz) variedad MCol 2066
Authors: Cantero Guevara Miriam Elena , Pardo Plaza Yuri Janio
Published: July 2023

Las raíces de yuca se usan en la alimentación humana y animal, como raíces frescas o transformadas industrialmente. En algunos países y zonas colombianas el aumento en la producción se ve limitado, debido a que no se cuenta con la tecnología y conocimientos suficientes para contribuir a la demanda actual de yuca. El objetivo de este estudio fue evaluar el efecto del ácido 1-naftalenacético sobre algunas variables de rendimiento de yuca variedad MCol 2066 (chirosa), mediante la aplicación de tres tiempos de inmersión (5, 10, 20 min) en cuatro concentraciones de ácido 1-naftalenacético (0, 100, 200, 300 ppm). Los datos se colectaron a los 240 días después de la siembra. Las variables porcentaje de almidón, materia seca, y masa fresca de raíces, presentaron diferencias significativas entre tratamientos. Los valores más altos se observaron en el tratamiento a 20 min de inmersión en 200 ppm de ácido 1-naftalenacético para las variables, almidón (45,56%), materia seca (51,6%), y masa fresca (73.270 kg/ha). A las condiciones del estudio el tratamiento en mención fue el mejor inductor para aumentar el rendimiento del cultivo de yuca.
Resistencia de genotipos de ñame Dioscorea spp a la antracnosis Colletotrichum gloeosporioides Penz
Authors: Campo Arana Rodrigo Orlando , Obando Echevarría Martín , Pérez Polo Dairo
Published: July 2023

El ñame Dioscorea spp., es un cultivo de importancia económica en el Caribe colombiano, hace parte de la dieta alimenticia y del sustento para los productores. La antracnosis Colletotrichum gloeosporioides es una de las enfermedades más limitantes de la producción del ñame, reportándose en Colombia pérdidas entre el 50 y 100  %. Se evaluó la resistencia a la antracnosis en 84 accesiones de D. alata y 28 de D. rotundata, pertenecientes a la colección de ñame de la Universidad de Córdoba, a los 120, 150 y 180 días después de la siembra (DDS), empleando una escala de severidad de 0-6. Las accesiones fueron clasificadas por su resistencia, empleando el método de la suma de rangos del área bajo la curva de progreso ABCPE y el método de la severidad a los 120, 150 y 180 DDS. Se ajustó La severidad a los 180 DDS tuvo fuerte relación lineal r = 0,99 con la variable integral área bajo la curva de progreso de la enfermedad ABCPE y la tasa de progreso de la enfermedad TPE. La clasificación de la resistencia por el método de la suma de rangos fue la más eficiente identificando en D. alata 18 accesiones resistentes R, 24 moderadamente resistente MR, 26 moderadamente susceptible MS y 16 susceptibles S. En la especie D. rotundata se identificaron 5 accesiones R, 8 MR, 8 MS, 6 S. La colección de ñame de la Universidad de Córdoba tiene accesiones con resistencia a la antracnosis, siendo importante iniciar con estas accesiones trabajos de mejoramiento, para identificar sus características agronómicas.
Critical Study of Amina Wadud's Thought in the Issue of Inheritance
Authors: Zenrif Fauzan , Bachri Syabbul
Published: July 2023

This study aims to examine the main arguments presented by Amina Wadud on inheritance in her book "Quran and Women" and evaluate the validity of her arguments. The scope of this research will include an analysis of Wadud's method of interpreting the Quran as outlined in the book Quran and Women which influenced her thoughts on Islamic inheritance and a critical study of her thoughts. This research is a type of qualitative research with a critical study approach. The results of the study show that a critical study of Wadud's thinking shows that she generalizes the 2:1 provision on the shares of men and women which actually only applies in certain cases. In addition, Wadud's demands for reinterpretation cannot be done without adequate interpretive science tools. Science explains that justice need not be interpreted as equality. There are two categories of justice, according to Aristotle: commutative justice and distributive justice. So that there can be no justification for questioning the Quran's just inheritance allocation. Furthermore, the provisions in the inheritance verse in the Quran are qath'i provisions so there is no justification for doing ijtihad which is presumptive (dzanny) in a reassuring text (qath'i). In addition, Wadud's thoughts are also considered less specific and do not provide a real format for how the redistribution she proposes. Therefore, Wadud's rereading in terms of inheritance is considered incomplete or incomprehensive of the Qur'an.
Screening Ethanol-Producing Yeast Origin from Pineapple Honey Ananas comosus (L.) Merr var Quenn
Authors: Sutoyo Sutoyo , Siswanto Siswanto
Published: July 2023

The availability of fossil-based fuels will gradually decrease while the amount required increases. This has prompted research to find alternative energy sources, including bioethanol. Bioethanol, as an alternative energy source, can be used as a transportation fuel better than fossil-based fuels because ethanol has a high octane number, laminar velocity and heat of vaporisation. Meanwhile, the level of carbon and hydrocarbon emissions is low so it can increase combustion efficiency in vehicles. In addition, the use of bioethanol as fuel is environmentally friendly and renewable. Ethanol can be produced through a fermentation process using ethanol-producing yeast.  Pineapple honey is known for its high sugar and other nutrient content, so it is supposed that many types of yeast can grow well in it. This study aims to isolation and screening of bioethanol-producing yeast from Pineapple Honey. This study was carried out by yeast isolation method, primary yeast screening, secondary yeast screening, and characterisation of selected yeast isolates. Data on ethanol production by yeast isolates were analysed by ANOVA with α=0.05 using the R studio program. This primary isolation and screening phase found eight yeast isolates capable of fermenting glucose and producing acid and gas in the test medium. Test ethanol production in DPE medium with 18% glucose content on all isolates showed that all isolates could produce ethanol with a range of 4.20-10.35%. Isolates of IK4 showed the highest ethanol production ability (10.35%) (p<0.5%) in significant contrast to the other seven isolates. Based on macroscopic and microscopic morphological characterisations, IKM 4 isolates show similarities to the genus Saccharomyces

Keywords: ethanol, pineapple, yeasts
Social networks and food choice of adolescents from a school in the Lisbon region
Authors: Almeida Ana Carina , Sousa Bruno
Published: July 2023

The use of social networks (SNs) leads to the development of autonomy and identity construction by young people, which may influence their food choices. The aim of this cross-sectional observational quantitative study was to determine the relationship between SNs and food choices of adolescents from a secondary school in the Lisbon region, according to the time of SN use. Data were collected at school using a Google Forms questionnaire for adolescents aged 16-19 years who used SNs. A sample of 176 participants was obtained. Of these adolescents, 60.2% used SNs less than four hours daily, while 39.8% used SNs more than four hours. In the lower SN usage group, the majority were boys (53.80%), while the majority were girls (61.40%) in the higher usage group (p<0.05). No statistically significant differences between adolescents who use the SNs less than or more than four hours daily were detected. In this study, no relationship was found between time in SNs and adolescents' food choices. Further studies on this topic will be necessary. Keywords: Adolescents, food choices, Lisbon, social networks
Contributions, limitations, and challenges of self-regulated learning in the educational context
Authors: Boruchovitch Evely , Simão Ana Margarida Vieira da Veiga , Frison Lourdes Maria Bragagnolo
Published: July 2023

Self-regulated learning is an important multidimensional construct in contemporary Educational Psychology, since it encompasses several dimensions essential to strategic learning. It has received increased attention from researchers and educators. In this sense, this article aims to reflect upon the contributions, limitations, and challenges of this theoretical framework in educational contexts in Brazil, Portugal, and the United States. More precisely, it aims to identify its main authors, areas, variables, and most researched domains. It also intends to characterize the main types of research designs, the most used instruments, the impact of the theme on publications and on the organization of events, as well as to examine its current challenges and future paths. We hope to contribute to a better understanding of self-regulated learning in different cultures, as well as to make useful considerations that can guide pedagogical practices and formative actions in Education.
O jogo como eixo de um programa experimental de formação continuada para pedagogos com a música
Authors: Nassif Silvia Cordeiro , Andrade Erika Natacha Fernandes
Published: July 2023

Este artigo apresenta a análise de um programa experimental de formação continuada elaborado para pedagogos na área da música; o eixo central das formações foi o jogo, considerando o seu potencial para mediar a construção de atitudes, fluências e saberes musicais. A análise mostra que o jogo é reconhecido como parte da função unidocente; é uma via para a aproximação dos pedagogos com a música, ajudando-lhes trazer à consciência generalidades conceituais específicas, facultando-lhes a criação de atividades com a música adaptadas às próprias possibilidades. As conclusões indicam que os pedagogos reconhecem que os saberes musicais compõem sua profissionalidade; os unidocentes se interessam mais pelo trabalho musical intencional na medida em que refletem a atividade com jogo e música tendo em vista as especificidades das crianças nos diferentes momentos do desenvolvimento e o impacto da música para a formação humanizada e integral.
Práticas pedagógicas com robótica educacional nos anos iniciais
Authors: Kaminski Márcia Regina , Boscarioli Clodis
Published: July 2023

Atividades de Robótica nos ambientes escolares têm sido alvo de discussão e investigação no âmbito das tecnologias digitais na educação. Todavia, são poucos os contextos que conseguiram implementar essas atividades como parte de seus Projetos Políticos Pedagógicos, de modo a desenvolvê-las sob uma perspectiva de progressão e continuidade dos conceitos, sendo a maior parte dos artigos publicados, experiências pontuais e trabalhos de curta duração. Nesse sentido, este artigo descreve resultados de um estudo de caso realizado em uma escola pública que atende estudantes do Ensino Fundamental I, pioneira na sua rede de ensino a implementar a Robótica Educacional. O estudo de caso realizado teve por objetivo apresentar as práticas pedagógicas desenvolvidas com Robótica Educacional e indicar caminhos e possibilidades para a implementação dessas atividades. As práticas iniciadas em 2015, continuam em andamento na perspectiva de desenvolvimento de criatividade, autonomia e habilidades socioemocionais, e têm servido como referência para a implementação da Robótica em outras unidades de ensino. Os resultados apontam que é possível realizar um trabalho investigativo e colaborativo na perspectiva de progressão dos conceitos de mecânica, eletrônica e programação, no qual o estudante é o protagonista.
IA na educação
Authors: Gonsales Priscila , Kaufman Dora
Published: July 2023

O artigo analisa a evolução da inter-relação entre educação e tecnologia, a partir da compreensão do atual desenvolvimento da inteligência artificial (IA) e do fenômeno big data. No Brasil, a história da educação com tecnologia está bastante relacionada à busca de um protagonismo do estudante, na qual o "aprender a programar" surge como principal símbolo de pró-atividade e fomento à postura criativa. "Aprender a programar" tornou-se praticamente meta na maioria dos projetos integrativos com tecnologia, baseados na lógica de programação que detém o controle do processo de execução algorítmica. As novas aplicações da IA a partir de 2012, mais precisamente a técnica de redes neurais profundas (deep learning), alteraram a lógica dos algoritmos deslocando o ponto focal dos códigos "programados" para o modelo automatizado que identifica padrões a partir dos dados. Cenário ainda pouco familiar à maioria dos educadores e gestores da educação, conecta-se o conceito de alfabetização midiática e informacional. O uso da IA na educação não pode nem deve ser determinado pelo caráter utilitário, mas sim fomentar oportunidades de formação para a vida cidadã contemporânea.
Tourism sustainability, Official Mexican Standards and the fulfillment of the human right to a healthy environment: Hydrocarbons, plastics, and bioremediation
Authors:   Universidad Autónoma de San Luis Potosí, Facultad de Derecho, Mendezcarlo Silva Violeta , Lizardi-Jiménez Manuel Alejandro ,   Consejo Nacional de Ciencia y Tecnología-Universidad Autónoma de San Luis Potosí
Published: July 2023

The negative effects of tourism have led to urban, environmental, and social deterioration in various Mexican tourist destinations. Biotechnology can provide some technical alternatives for hydrocarbon and plastic pollution with promising results of bioremediation. However, the scientific approach apparently is insufficient due to the magnitude of environmental concerns regarding these materials. In this work, remediation and prevention are studied. Therefore, Official Mexican Standards that directly address environmental problems, particularly those generated by hydrocarbons and microplastics, are necessary.
Characterization of Obtained extracts and Bark Residues from Black Alder (Alnus glutinosa) and Pine (Pinus sylvestris) after Microwave-Assisted Water Extraction under Different Conditions
Authors: Ponomarenko Jevgenija , Pals Matiss , Lauberts Maris , Arshanitsa Alexandr
Published: July 2023

This publication investigates the potential application of bark extractives as a biopolyol and extracted bark residues as a filler for producing polyurethane materials. The aim is to enhance the properties of polymeric composites while reducing the environmental impact associated with the complex utilization of bark.The comprehensive study of compositions of extractives isolated from black alder (Alnus glutinosa) and Baltic pine (Pinus silvestris) barks was performed using microwave-assisted water extraction. The yield of the extracts obtained under different extraction conditions, as well as the total phenolic and monomeric carbohydrate content in the extractives, were studied. Furthermore, UHPLC-HRMS analysis was conducted to study the detailed composition of the bark extracts.The total content of hydroxyl groups and the relative portion of aliphatic and phenolic groups in the isolated extracts were determined depending on the extraction regimes and bark origination. The dominant compounds in black alder bark extracts isolated at 70-90⁰C were identified as diarylheptanoids and their derivatives bearing sugar units, with oregonin being the main compound. Pine bark extracts isolated at the same temperature were found to be rich in oligomeric proanthocyanidins. Extracts from both black alder and pine barks obtained at different times of isothermal heating between 130-150°C were rich in carbohydrates and showed an increased proportion of aliphatic OH groups.The study also focused on the composition of residual biomass. It was indicated by Py-GC/MS/FID and wet chemistry methods that residues of both black alder and pine bark are enriched with lignin in comparison with initial barks. Therefore, it can be proposed that extracted bark residues introduced into polyurethane compositions will act as a charcoal formation promoter, thus increasing the flame resistance of materials.Overall, the study provides valuable insights into the chemical composition of bark extractives and extracted bark residues for their potential application as biopolyol and fillers of polyurethane materials, contributing to a more sustainable approach in polymer composite production.
Heartland Virus: An Evolving Story Of An Emerging Zoonotic And Vector-Borne Disease
Authors: Mantlo Emily K. , Haley Nicholas J.
Published: July 2023

Heartland virus (HRTV) is an emerging tick-borne bandavirus that is capable of causing severe disease characterized by acute thrombocytopenia and lymphopenia. The virus is endemic to the eastern United States, and is carried by the Lone Star tick (Amblyomma americanum). Since its discovery in 2009, at least 60 human infections have been recorded across this area, with an overall 5-10\% estimated mortality rate. All infections reported thus far have occurred following a known tick bite or exposure to tick-infested areas, but the possibility of nosocomial transmission has not been ruled out. Despite relatively high rates of seroprevalence among certain wildlife species such as white-tailed deer, the reservoir species for HRTV remains unknown, as the virus has never been isolated from any mammalian wildlife species. Furthermore, how the virus is transmitted to its vector species in nature remains unknown, though laboratory studies have confirmed both horizontal and vertical transmission of HRTV in A. americanum. In addition, the recent 2017 introduction of the Asian longhorned tick (Haemaphysalis longicornis) to the US has raised concerns about possible spillover of HRTV into a new tick species that has been confirmed to be a competent vector for HRTV in the laboratory. Thus, an increased awareness of its clinical presentation is needed, and further research is urgently required to establish the natural transmission cycle and develop new countermeasures for this novel zoonotic pathogen
Cooling Energy Benefits of Increased Green Infrastructure in Subtropical Urban Building Environments
Authors: Mohammed Afifa , Khan Ansar , Khan Hassan Saeed , Santamouris Mattheos
Published: July 2023

Due to urban warming, energy demand for cooling buildings is rising. The current study used CitySim to estimate the cooling energy requirements for 40 buildings in Downtown, Dubai using high-resolution climate data from weather research and forecasting (WRF) coupled with single layer urban canopy model (SLUCM). Simulating the four mitigation scenarios allowed for the examination of the reduction in cooling load caused by the addition of greenery at a rate ranging from 25% to 100%. The insulated building's cooling demand reduced by a maximum of 13.89% under 100% GI (M4). Scenario M4 resulted in a reduction of 4.6 kWh/m2 and 3.1 kWh/m2 for the non-insulated and insulated low-rise residential buildings, respectively, while the high-rise buildings saw a reduction of 3.09-4.91 kWh/m2 for the non-insulated and 2.07-3.09 kWh/m2 for insulated buildings. This study offered a potential remedy to deal with the problem of urban heating in subtropical environments.
Optimising Hollow Structured Silicon Nanoparticles for Lithium-Ion Batteries
Authors: Yue Chenghao , Liu Yao , Guan Shaoliang , Fereydooni Alireza , Zeng Yuexi , Wei Zhijie , Wang Yonggang , Chao Yimin
Published: July 2023

Silicon has been proved to be one of the most promising anode materials for the next generation of lithium-ion battery. For the application in batteries, Si anode should have high capacity and must be industrially scalable. In this study, we have designed and synthesised a hollow structure to meet these requirements. All the processes are carried out without special equipment. The Si nanoparticles that are commercially available are used as the core sealed inside TiO2 shell, with rationally designed void space between the particles and shell. The Si@TiO2 are characterised using X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), and scanning electron microscope (SEM). The optimised hollow structured silicon nanoparticles, when used as anode in lithium-ion battery, exhibit a high reversible specific capacity over 600 mAhg-1. This excellent electrochemical property of the nanoparticles can be attributed to their optimised phase and unique hollow nanostructure.
Dissolution Behaviour of Bark Extractives in Polyurethane Synthesis Media: A Comprehensive Study
Authors: Arshanitsa Alexandr , Lauberts Maris , Pals Matiss , Ponomarenko Jevgenija
Published: July 2023

The production of polyurethane films from bark-derived polyols requires the complete solubility of all components in the polyurethane synthesis media. In this study, a comprehensive investigation was conducted to achieve the copolymerization of black alder bark water extract-derived polyol with isocyanate for polyurethane film synthesis in THF solution. A fractionation approach using tetrahydrofuran (THF) as a solvent was employed to dissolve the extract, followed by filtration and removal of the solvent. The resulting THF-soluble fraction comprised 62±1% of the dry weight of the alder bark extract, mainly consisting of the xyloside form of the diarylheptanoid compound oregonin, along with oligomeric flavonoids and carbohydrates. The THF-insoluble fraction was the most enriched with carbohydrate compounds, followed by the crude extract and THF-soluble fraction. Another approach was aimed at obtaining bark extractives based liquid polyols suitable for producing rigid PU foams. For this purpose, oven-dried crude black alder bark water extract was liquefied with polyethylene glycol (PEG 400). The liquefaction of black alder bark and pine bark extractives was studied under different conditions, including varying temperature ranges (130-170⁰C), catalyst concentrations (0-1,5%), and bark extract content in the mixture (15-30%). The results showed that the use of sulphuric acid as a catalyst (1-1.5%) significantly improved the solubility of both extractives, enabling the attainment of extract concentrations up to 25% at 170⁰C. However, increasing the extract content beyond a certain threshold led to incomplete solubility. It was shown that the PEG-insoluble fractions consist mainly of carbohydrate components. To increase the content of biomass in liquid polyols, the effect of glycerol additions into the liquefaction agent is under study. The findings provide insights into tailoring bark-sourced polyols for polyurethane foam production through appropriate liquefaction conditions.
Feasibility of Ultra–Wideband Channels at Millimeter Wavelengths Faded by Rain in GeoSurf Satellite Constellations
Authors: Matricciani Emilio , Magarini Maurizio , Riva Carlo
Published: July 2023

Keywords: Baseband, GeoSurf Constellation, Interference, Linear Distortions, Passband, Time Delay, Rain attenuation, Synthetic Storm Technique, ultra–wideband.
The Optimal Impregnation Amounts of Flame-Retardant for Korean Larch and Japanese Cedar Building Materials
Authors: Jo Seok-Un , Chae Hak-Byeong , Park Hee-Jun , Jang Eun-Suk
Published: July 2023

In accordance with regulations set forth by the Ministry of Land, Infrastructure, and Transport in Korea regarding the "Flame Retardant Performance of Building Finishing Materials and Fire Spread Prevention Structure," it is mandated that semi-noncombustible materials have a total heat emission less than 8 MJ/m2. Consequently, our study aimed to determine the ideal quantity of flame-retardant treatment required to meet the fire safety standards for Korean larch and Japanese cedar, commonly used exterior materials in Korean construction. To this end, we investigated using a cone calorimeter to observe changes in the THR (Total Heat Released) based on the AFI (Amount of Flame-retardant Impregnation) in Korean larch and Japanese cedar. Our findings indicated that the AFI needed to satisfy the prescribed flame-retardant standard of 8 MJ/m2 was THR 299 MJ/m2 for Korean larch and THR 526 MJ/m2 for Japanese cedar. As a result, we established optimal impregnation levels of flame retardant for both species.
Humoral Response to Dengue Virus Infections Potentiates Antibody-Dependent Enhancement of SARS-CoV-2
Authors: Lechuga Guilherme C , Temerozo Jairo R , Napoleão-Pêgo Paloma , Bou-Habib Dumit C , Morel Carlos M , Provance-Jr David W , Souza Thiago M.L. , De-Simone Salvatore Giovanni
Published: July 2023

Despite successful vaccination efforts, the emergence of new SARS-CoV-2 variants poses ongoing challenges to control COVID-19. Understanding humoral responses concerning SARS-CoV-2 infections and their impact is crucial for developing future vaccines that are effective worldwide. Here, we identified 41 immunodominant linear IgG B-cell epitopes in its Spike glycoprotein with a SPOT synthesis peptide array probed with a pool of serum from hospitalized COVID-19 patients. Bioinformatics showed a restricted set of epitopes unique to SARS-CoV-2 compared to other coronavirus family members. Potential crosstalk was also detected with Dengue virus (DENV), confirmed by screening individuals infected with DENV before the COVID-19 pandemic in a commercial ELISA assay for anti-SARS-CoV-2 antibodies. Higher reactivity indices were often measured in individuals with a pre-pandemic dengue infection than those with COVID-19. A high-resolution evaluation of antibody reactivity against peptides representing epitopes in the spike protein identified ten sequences in the NTD, RBD, and S2 domains. Functionally, antibody-dependent enhancement (ADE) in SARS-CoV-2 infection of monocytes was observed with pre-pandemic dengue-positive sera. A significant increase in viral load was measured compared to controls, with no detectable neutralization or considerable cell death, suggesting its role in viral entry. This study highlights the importance of identifying the epitopes generated during the humoral response to a pathogenic infection to understand the potential interplay of previous and future conditions on disease. Vaccine development and optimization strategies should be mindful of the potential for A.D.E. that could differ geographically due to endemic biological risks.
EvolveNet: Evolving Networks by Learning Scale of Depth and Width
Authors: Shibu Athul , Lee Dong-Gyu
Published: July 2023

Convolutional Neural Networks (CNNs) are largely hand-crafted, which leads to inefficiency in the constructed network. Various other algorithms have been proposed to address this issue, but the inefficiencies resulting from human intervention have not been addressed. Our proposed EvolveNet algorithm is a task-agnostic evolutionary search algorithm that can find optimal depth and width scales automatically in an efficient way. The optimal configurations are not found using grid search, instead evolved from an existing network. This eliminates inefficiencies that emanate from hand-crafting, thus reducing the drop in accuracy. The proposed algorithm is a framework to search through a large search space of subnetworks until a suitable configuration is found. Extensive experiments on the ImageNet dataset demonstrate the superiority of the proposed method by outperforming the state-of-the-art methods.
Polydeoxyribonucleotide and Shock Wave Therapy Sequence Efficacy in Regenerating Immobilized Rabbit Calf Muscles
Authors: Lee Yoon-Jin , Moon Yong Suk , Kwon Dong Rak , Cho Sung Cheol , Kim Eun-Ho
Published: July 2023

Objective: The main purpose of the study is to investigate the combined effects of polydeoxyribonucleotide (PDRN) and extracorporeal shock wave therapy (ESWT) sequences on the regenerative processes in atrophied animal muscles.
Methods: Thirty male New Zealand rabbits, aged 12 weeks, were divided into five groups: normal saline, PDRN, ESWT, PDRN injection before ESWT, and PDRN injection after ESWT. Following 2 weeks of cast immobilization, the respective treatments were administered to the atrophied calf muscles. Radial ESWT was performed twice weekly. The evaluation included measurements of calf circumference, tibial nerve compound muscle action potential (CMAP), and gastrocnemius (GCM) muscle thickness after 2 weeks of treatment. Histological and immunohistochemical staining, as well as Western blot analysis, were conducted 2 weeks post-treatment. Staining intensity and extent were assessed using semi-quantitative scores.
Results: Groups 4 and 5 demonstrated significantly greater calf muscle circumference, GCM muscle thickness, tibial nerve CMAP, and GCM muscle fiber cross-sectional area (types I, II, and total) than in the remaining three groups (p < 0.05), while they did not did not differ significantly in these parameters. Groups 2 and 3 showed the higher values for all the observations compared to group 1 (p < 0.05). Group 4 had the greatest ratio of vascular endothelial growth factor (VEGF) to platelet endothelial cell adhesion molecule-1 (PECAM-1) in the gastrocnemius muscle fibers than in the other four groups (p < 0.05). Western blot analysis revealed significantly higher expression of angiogenesis cytokines in groups 4 and 5 than in the remaining (p < 0.05).
Conclusion: The combination of ESWT and PDRN injection demonstrated superior regenerative efficacy for atrophied calf muscle tissue in rabbit models than these techniques alone or saline. Particularly, administering ESWT after PDRN injection yielded the most favorable outcomes in specific parameters.
VACCINATON POLICIES IN SOLID ORGAN TRANSPLANT ADULT CANDIDATES AND RECIPIENTS
Authors: Viganò Mauro , Beretta Marta , Lepore Marta , Abete Raffaele , Benatti Simone Vasilij , Grassini Maria Vittoria , Camagni Stefania , Chiodini Greta , Vargiu Simone , Vittori Claudia , Iachini Marco , Terzi Amedeo , Neri Flavia , Pinelli Domenico , Di Marco Fabiano , Ruggenenti Piero , Rizzi Marco , Colledan Michele , Fagiuoli Stefano
Published: July 2023

Prevention of infections is crucial in solid organ transplant (SOT) candidates and recipients. These pa-tients are exposed to an increased infectious risk due to previous organ insufficiency and to pharmaco-logic immunosuppression. Besides infectious-related morbidity and mortality, this vulnerable group of patients is also exposed to the risk of acute decompensation and organ rejection or failure in the pre- and post-transplant period respectively, since antimicrobial treatments are less effective than in the immunocompetent patients. Vaccination represents a major preventive measure against specific infec-tious risks in this population but as responses to vaccines are reduced, especially in the early post-transplant period or after treatment for rejection, an optimal vaccination status should be obtained prior to transplantation whenever possible.
This review reports the currently available data on the indications and modalities of vaccination in SOT adult candidates and recipients.
A Lesson from a Measles Outbreak in Healthcare Workers in a Single Hospital in South Korea: The Importance of Knowing the Prevalence of Susceptibility
Authors: Choi Sungim , Chung Jae-Woo , Chang Yun Jung , Lim Eun Jung , Moon Sun Hee , Do Han Ho , Lee Jeong Hun , Cho Sung-Min , Kwon Bum Sun , Chung Yoon-Seok , Park Seong Yeon
Published: July 2023

Background
Despite the high vaccination coverage rate, in-hospital transmission of measles continues to occur in South Korea. We present a measles outbreak in which two healthcare workers (HCWs) with presumptive evidence of measles immunity were infected by a patient with typical measles at a single hospital in South Korea. This facilitated the evaluation of measles seroprevalence in all HCWs.

Methods
In 2018, suspected patients and contacts exposed during a measles outbreak were investigated based on their medical histories and vaccination status. Cases were confirmed by the detection of measles-specific immunoglobulin M or RNA. After the measles outbreak, all HCWs underwent measles IgG testing for point-prevalence surveillance. In addition, we have routinely performed measles IgG tests on new HCWs since 2019. The measles vaccine was administered to HCWs who tested negative or equivocally negative for IgG antibodies.

Results
An index patient who returned from China with fever and rash was diagnosed with measles at a hospital in Korea. Two additional HCWs were revealed as measles cases: one was vaccinated with the 2-dose measles–mumps–rubella (MMR) vaccine, and the other, who was born in 1967, was presumed to have immunity from natural infection in South Korea. All three patients harbored the same D8 genotype. No additional measles cases were identified among the 964 contacts of secondary patients.
After the measles outbreak, 2,310 HCWs underwent measles IgG tests. The average age at the time of the test was 32.6 years, and 74.3% were female. The overall seropositivity of measles was 88.9% (95% confidence interval, 87.5 –90.1). Although the birth cohorts between 1985 and 1994 were presumed to have received the measles-rubella (MR) catch-up vaccination in 2001, 175 (89.3%) HCWs were born after 1985 among the 195 seronegative cases.

Conclusion
Despite high population immunity, imported measles transmission occurred among HCWs, with presumed immunity. This report underscores the importance of understanding the prevalence of measles susceptibility among newly employed HCWs. This is important for policymaking regarding hospital-wide vaccinations to prevent vaccine-preventable diseases.
Economic significance of detection and laboratory confirmation of inherited chromosomally integrated Human Herpesvirus 6A/B in newborns
Authors:   Central Research Institute of Epidemiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, Russian Federation, Domonova E.A. , Voronin E.M. ,   Central Research Institute of Epidemiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, Russian Federation, Melekhina E.V. ,   Central Research Institute of Epidemiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, Russian Federation, Chugunova O.L. ,   N.I.Pirogov Russian National Research Medical University, Moscow, Russian Federation, Cherkasova S.V. ,   N.I.Pirogov Russian National Research Medical University, Moscow, Russian Federation, Zaplatnikov A.L. ,   Russian Medical Academy of Continuing Professional Education, Moscow, Russian Federation, Dementyev A.A. ,   Russian Medical Academy of Continuing Professional Education, Moscow, Russian Federation, Tvorogova M.G. ,   Central Research Institute of Epidemiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, Russian Federation, Akimkin V.G. ,   Central Research Institute of Epidemiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, Russian Federation
Published: July 2023

Overdiagnosis of congenital infections caused by Human Herpesvirus 6A/B (HHV-6A/B) in newborns with an inherited chromosomally integrated (ici) HHV-6A/B creates an unreasonable economic burden for the healthcare system and society. We assessed economic significance of detection and laboratory confirmation of iciHHV-6A/B in newborns with congenital infections during their inpatient treatment in Moscow in 2020. The introduction of a new method based on the quantitative detection of HHV-6A/B DNA in patient’s whole blood sample, nail plates and/or hair follicles by a real-time polymerase chain reaction will result in an economic effect with a minimum ratio of 1:68, will reduce healthcare costs in Moscow and optimize the epidemiological surveillance of vertically congenital infections in the region. The total estimated economic costs averted (including costs of pharmacotherapy, as well as clinical, laboratory, and instrumental examinations and other medical procedures in maternity and obstetric hospitals) will be approximately 6 million rubles per year for Moscow. Key words: economic significance, economic costs averted, Human Herpesvirus 6A/B, inherited chromosomally integrated Human Herpesvirus 6 A/B, newborns, congenital infections
First experience of using casirivimab/imdevimab in COVID-19 in the Russian Federation
Authors:   M.F.Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russian Federation, Bogomolov P.O. ,   Group of companies "United Medical Systems", Moscow, Russian Federation, Bueverov A.O. ,   M.F.Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russian Federation,   Group of companies "United Medical Systems", Moscow, Russian Federation,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation, Bueverova E.L. ,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation, Кhvan A.A. ,   Group of companies "United Medical Systems", Moscow, Russian Federation, Maev I.V. ,   A.I.Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russian Federation, Arapova M.V. ,   Group of companies "United Medical Systems", Moscow, Russian Federation, Shub N.A. ,   Group of companies "United Medical Systems", Moscow, Russian Federation, Isaeva E.A. ,   M.F.Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russian Federation, Koblov S.V. ,   M.F.Vladimirsky Moscow Regional Research Clinical Institute, Moscow, Russian Federation
Published: July 2023

The lack of effective etiotropic therapy is a serious challenge in the treatment of patients with COVID-19. The recent emergence of a new class of medications neutralizing monoclonal antibodies against the SARS-CoV-2 spike protein allows to partially solve this problem. This article presents a clinical case of a patient with an increased risk of COVID-19 complications (paroxysmal atrial fibrillation, atherogenic dyslipidemia, impaired carbohydrate tolerance) who was treated with 600 mg casirivimab and 600 mg imdevimab by intravenous infusion. A significant improvement in the patient's well-being was noted within the first 24 hours: normalization of body temperature, stool, reduction of weakness, disappearance of arthralgia and myalgia. After 48 hours, a negative test result for SARS-CoV-2 RNA was obtained, which altogether made it possible to state the recovery. There were no adverse events during and after therapy. The casirivimab and imdevimab monoclonal antibody combination may be considered as a promising etiotropic treatment for COVID-19. Key words: COVID-19, monoclonal antibodies, casirivimab, imdevimab, treatment
Enterovirus infections: current state of the problem
Authors:   Kuban State Medical University, Krasnodar, Russian Federation, Tkhakushinova N.Kh. ,   Specialized Clinical Children's Infectious Diseases Hospital of the Ministry of Health of the Krasnodar Territory, Krasnodar, Russian Federation, Shaturina T.T. ,   Kuban State Medical University, Krasnodar, Russian Federation,   Specialized Clinical Children's Infectious Diseases Hospital of the Ministry of Health of the Krasnodar Territory, Krasnodar, Russian Federation
Published: July 2023

In this review, we analyze the whole spectrum of the current state of the problem of enterovirus infection in the world and in one of the regions of the Russian Federation, namely Krasnodar region. We discuss the currently used classification of enterovirus infections, clinical manifestations, new approaches to diagnosis, treatment, and prevention. Key words: enterovirus infection, serotype, poliovirus
The Prospects and Challenges of Biopolymers for Enhanced Oil Recovery (EOR)
Authors: Matovanni Maudy Pratiwi Novia , Ikhsanudin Muhammad Nur , Arvianto Rizky Ibnufaatih , Waluyo Joko , Distantina Sperisa , Kaavessina Mujtahid , Pranolo Sunu Herwi
Published: July 2023

ABSTRACT. Currently, Enhanced Oil Recovery (EOR) technology is being interested in the Indonesian state as an advanced technology that can recover oil remaining in the reservoir. The discovery of new resources and EOR efforts are predicted to result in increased oil production. This paper provides a review of main types of EOR methods, which are gas injection, thermal injection, and chemical injection; mechanism of polymer flooding; and biopolymer materials for EOR, attention were given to xanthan gum, cellulose, guar gum, and lignin. Polymer flooding is a low-cost chemical injection method with a high rate of success. Polymer flooding has several advantages, including improving oil recovery by minimizing residual oil saturation, decreasing water output from oil well, and requiring less water compared with water flooding. Since the use of polymer flooding in the EOR activities, there is a lot of potential that biopolymers are materials that play a significant role in the application of EOR technology, because environmentally friendly properties and have advantages over synthetic polymers. Biopolymer can be modified to nano materials or grafted with synthetic polymer to improve its properties and stability. It have shear, salinity, and temperature resistance, long-term stability, and large availability, so it making the right choice for applications in oil recovery.

Keywords: enhanced oil recovery, EOR, biopolymer, polymer flood, modification of biopolymer
Students’ Performance in Writing English Exposition Text of the Eleventh Graders of SMAN 13 Jakarta
Authors: Wijayanti Katarina Kriheni , Permana Sudarya
Published: July 2023

This article analyzed the understanding of eleventh graders' students at SMAN 13 Jakarta regarding the exposition text. The purpose of this paper was to find out to what extent the comprehension of eleventh graders of students of exposition text through the levels in the Blake Education rubric. The analysis table developed by Blake Education (1998) was used for the essay text analysis process. From the four main indicators studied, the results of this study indicated that (1) the average student was already at level 2, which could be categorized as an understanding of the exposition text; (2) although the average in both the Natural Sciences Program and Social Sciences Program was at level 2, the data showed that the students of Natural Science Program understood the exposition text better than the students of Social Science Program did. This paper also provided evidence regarding the difficulties of students in writing exposition texts. These findings showed that the ability of students to write exposition texts was in the middle or average level.
TINJAUAN VARIABEL REFRIGERANT VOLUME
Authors: Rachman Arfidian , Yuana Dewi Arfita , Effendi Asnal , Nesti Lisa
Published: July 2023

Sistem VRV adalah sistem HVAC multi-split yang mempertahankan porsi berbeda dengan memvariasikan volume refrigeran. Sistem ini mengontrol volume zat pendingin/refrigeran untuk efisiensi dan keandalan. Kajian ini bertujuan untuk mengidentifikasi elemen sistem VRV yang mempengaruhi faktor operasional dan kinerja. Studi sebelumnya sangat penting untuk pengembangan VRV skala besar di masa depan.
Ansiedad y procrastinación en el personal administrativo de una empresa privada de explosivos en la ciudad de Lima
Authors:   , Malásquez Valencia Frida Sofía
Published: July 2023

El estudio llevó por título ansiedad y procrastinación en el personal de una empresa privada de explosivos en la ciudad de Lima, el fin fué precisar el grado de ansiedad y procrastinación en la muestra. El estudio de tipo descriptivo, observacional de corte transversal y correlacional. Se trabajó con una muestra no probabilística de 60 colaboradores, teniendo como criterios de inclusión ser parte del personal contratado, pertenecer al staff administrativo y ser mayor de edad. También, se tuvo como criterio de exclusión el ser practicante o voluntario. A la población anteriormente detallada se le aplicó el Inventario de Ansiedad Estado – Rasgo (IDARE), creado por Spielberger, Gorsuch y Lushene en 1970, teniendo este un alfa de Cronbach de 0.92 en la escala Ansiedad – Estado y 0.87 en la escala Ansiedad-Rasgo. En relación a la Escala de Procrastinación General y Académico construida por Deborah Ann Busko, cuenta con un alfa de Cronbach de 0.87 permitiendo esto concluir que la escala presenta confiabilidad. Se concluyó que no existe correlación entre ansiedad y procrastinación, no existiendo conexión de sifnificancia entre la ansiedad rasgo y la procrastinación o aplazamiento de tareas en los colaboradores, existe un nexo no significativo entre la ansiedad estado y la procrastinación, cómo conclusión descriptiva se encontró un nivel de ansiedad bajo en 21 colaboradores, nivel medio en 24 y nivel alto en 15 en la población de muestra. En relación a la procrastinación se encontró nivel bajo en 26 colaboradores, nivel medio en 18 y nivel alto en 16.
Plan de negocios para la producción y venta de Agua Ozonizada en los hoteles del distrito de Miraflores
Authors:   , Cruz Ponce Mijael , Ludeña Perry Romina Alexandra , Quispe Lopez Gustavo Adolfo
Published: July 2023

Nuestro proyecto de investigación se va a comprender en la creación de un negocio, lo cual debe ser viable y aplicable. Nuestro negocio para realizar se dedicará la venta y distribución de agua ozonizada exclusivamente a los hoteles de cuatro y cinco estrellas, dicho emprendimiento tendrá por nombre Ozonic Agua, donde nos enfocaremos en los hoteles ubicados en Miraflores, distrito ubicado en la ciudad de Lima, para que poco a poco comenzamos a expandirnos. Unos de nuestros objetivos propuestos es conseguir ser empresa líder en nuestro rubro, ayudando a las personas con nuestro producto que le vamos a proporcionar y también aprovecharemos los canales de distribución y ventas que vamos a tener. Ejecutando las respectivas herramientas para una investigación como el estudio de mercado, tanto cualitativo y cuantitativo, podremos saber cuál serán los datos que necesitaremos para saber si nuestro mercado meta está satisfecho con nuestro producto. Nosotros queremos que la empresa que elaboramos sea rentable y económicamente estable, por eso también realizaremos análisis de estados financieros, balances generales y observar las ratios de rentabilidad, con la única finalidad de observar cómo camina nuestro negocio y evitar riesgos económicos. Finalmente, “OZONIC AGUA” tiene un compromiso firme con la salud de las personas, hoy más que nunca por la actual coyuntura que vivimos en el mundo. Todo esto es garantizado cumpliendo los protocolos observados y certificaciones de nuestros productos.