bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Prestasi dari Perspektif Manajemen: Studi Pada PT. Garuda Metalindo Tbk
Authors: Tiara Fauziah Tiara Anggraini , Nindika Sundayu Niken , Azzahra Sahira
Published: August 2023

Selama pandemi, hampir semua perusahaan menghadapi kondisi yang sulit dalam memperoleh pendapatan dan mencapai laba, dan hal ini juga berdampak pada PT Garuda Metalindo Tbk. Penelitian ini bertujuan untuk mengevaluasi kinerja keuangan perusahaan PT Garuda Metalindo Tbk dengan menggunakan data laporan keuangan sekunder yang telah dipublikasikan dari tahun 2019 hingga 2022. Laporan keuangan PT Garuda Metalindo Tbk di akses melalui website https://www.idx.co.id/. Analisis data menggunakan rumus rasio berdasarkan perspektif manajemen. Temuan penelitian terdapat nilai negatif dalam presentase laba usaha perusahaan pada tahun 2020 dan menunjukkan bahwa kinerja keuangan belum optimal karena terjadi peningkatan dalam jumlah piutang dan beban operasi yang mempengaruhi perolehan laba.
IMPLIKASI GERAKAN LITERASI SEKOLAH DENGAN MEDIA BUKU CERITA BERGAMBAR TERHADAP KARAKTER (AKHLAK) SISWA
Authors: Rosdiana Evi
Published: August 2023

Minat dan daya baca merupakan problematika laten yang terjadi pada peserta didik dan pendidik. Atas dasar ini, diterbitkan kebijakan pemerintah dalam Permendikbud Nomor 23 Tahun 2015 tentang Gerakan Literasi Sekolah (GLS). Adapun salah satu upaya yang diwajibkan, yakni kegiatan membaca 15 menit buku non-pelajaran setiap hari (buku cerita atau buku lainnya). Penelitian ini bertujuan untuk menganalisa implikasi gerakan literasi sekolah dengan media buku cerita bergambar. Adapun jenis penelitian ini ialah kualitatif dengan metode studi kepustakaan. Adapun bahan penelitian dan kajian analisa diperoleh melalui sumber referensi ilmiah, meliputi buku, artikel, prosiding, skripsi, tesis, dan disertasi. Sumber ilmiah tersebut diperoleh melalui laman kredibel, seperti Google Scholar, DOAJ, dan SINTA. Hasil penelitian ini menunjukkan bahwa kegiatan gerakan literasi sekolah melalui media buku cerita bergambar memberi dampak signifikan terhadap daya dan minat baca siswa. Hal ini ditinjau dari peningkatan wawasan pengetahuan siswa, motivasi membaca buku pada siswa, dan membentuk karakter giat literasi pada siswa. Adapun tahapan GLS, meliputi 15 menit membaca buku cerita bergambar pra-pembelajaran, membaca doa, membaca ayat al-Qur’an pada surah-surah pendek, menyanyikan lagu wajib nasional, serta penguatan dari guru terhadap materi ajar pertemuan sebelumnya. Dengan demikian, siswa semakin bergerak untuk terbiasa dan mencintai dunia literasi.
ANALISIS KEMAMPUAN DASAR MENGAJAR MAHASISWA UINSU MEDAN DALAM PELAKSANAAN PROGRAM PENGALAMAN PRAKTIK LAPANGAN III (Studi Kasus Pada MTs Al-Ittihadiyah Laut Dendang)
Authors: Daulay Sholihatul Hamidah , Nuraini Titi , Rahmadhani Viki , Amali Wahdini Rizki , Amal Muhammad Ichlasul
Published: August 2023

Penelitian dilakukan pada, mahasiswa Praktik Pengalaman Lapangan III UIN SU Medan Tahun Akademik 2022/2023. Penelitian bertujuan untuk mengetahui kemampuan mahasiswa dalam melaksanakan pembelajaran pada saat melakukan Praktik Pengalaman Lapangan III. Metode yang digunakan dalam penelitian adalah metode deskriptif dengan bentuk penelitian survei. Teknik pengumpul data yang digunakan adalah teknik komunikasi langsung dan teknik komunikasi tidak langsung dengan alat pengumpul data berupa panduan wawancara dan angket. Subjek penelitian adalah sekolah MTs Al Ittihadiyah Laut Dendang yang ada di Kecamatan Percut Sei Tuan di Medan. Hasil dari penelitian menunjukkan bahwa kemampuan dasar mengajar mahasiswa dalam melaksanakan Praktik Pengalaman Lapangan III cukup baik. Hal tersebut tampak padaperencanaan, pelaksanaan, dan evaluasi yang dilakukan mahasiswa dalam melaksanakan praktik.
UPAYA GURU BIMBINGAN DAN KONSELING DALAM MENINGKATKAN KONTROL DIRI SISWA DI MAN 5 MADINA
Authors: Lubis Armen Ependi , Khairuddin Khairuddin , OK Azizah Hanum
Published: August 2023

Penelitian ini tentang Upaya Guru Bimbingan dan Konseling dalam Meningkatkan Kontrol Diri Siswa di MAN 5 Madina. Latar belakang penelitian ini adalah masih banyaknya siswa yang kurang baik dalam pengendalian diri atau pengkontrolan diri. Penelitian ini bertujuan untuk mendeskripsikan apa saja upaya guru bimbingan dan konseling dalam meningkatkan kontrol diri siswa dan untuk mendeskripsikan apa saja hambatan-hambatan yang di alami guru bimbingan dan konseling dalam meningkatkan kontrol diri siswa di Madrasah Aliyah Negeri 5 Mandailing Natal. Penelitian ini merupakan penelitian kualitatif deskriptif. Subyek penelitiannya adalah guru bimbingan dan konseling dan beberapa orang siswa, metode pengumpulan data yang dilakukan melalui observasi, wawancara, dan dokumentasi. Kontrol diri yang banyak terjadi misalnya siswa kurang mengontrol sikap saat proses belajar, siswa sering berbicara dengan teman di sampingnya yang membuat guru mengeluh dengan sikap siswa, sehingga melibatkan guru bimbingan dan konseling membantu siswa agar mengontrol sikap saat belajar dan diluar proses belajar, seperti ikut dengan temannya membolos, dan ikut dengan temannya tawuran. Berdasarkan hasil penelitian dapat disimpulkan bahwa upaya guru bimbingan dan konseling dalam meningkatkan kontrol diri siswa adalah memberikan bimbingan, arahan, layanan kepada siswa, apabila bimbingan, arahan, dan layanan yang diberikan guru bimbingan dan konseling kepada siswa belum juga bisa mengubah siswa jadi lebih baik, maka guru bimbingan dan konseling akan melakukan kunjungan rumah, mengirim surat untuk orang tua siswa, agar datang ke sekolah, dan guru bimbingan dan konseling akan bertanya dahulu bagaimana perilaku siswa di rumah.
PERAN GURU BIMBINGAN KONSELING DALAM MEMBIMBING MANAJEMEN WAKTU MENGERJAKAN UKBM (UNIT KEGIATAN BELAJAR MANDIRI) DI MAN 3 MEDAN
Authors: Harahap Azur Aini , Nasution Fauziah , S Irwan
Published: August 2023

Manajemen waktu adalah waktu keterampilan dalam mengatur dan mengelola waktu dengan baik. Serta menjadikan waktunya lebih produktif dengan melakukan hal-hal yang dapat memberikan manfaat dirinya. Manajemen waktu memiliki peranan besar dalam keberhasilan belajar siswa. Rumusan masalah dalam penelitian ini adalah 1. Siswa tidak bisa mengatur waktu senggang dengan mengerjakan UKBM (Unit Kegiatan Belajar Mandiri). 2. Kurangnya kesadaran dan pemahaman siswa terhadap manajemen waktu. 3. Siswa mengalami kesulitan dalam mengatur waktu dengan efektif.

Jenis penelitian ini menggunakan analisis deskriptif kualitatif dan menggunakan subyek yang disebut informan yaitu guru BK, dan siswa kelas XI MIPA 6 MAN 3 Medan. Sumber data primer adalah guru BK, dan siswa. Sumber data sekunder adalah buku-buku atau hasil penelitian terdahulu yang dapat memberikan informasi terkait dengan judul penelitian. Teknik pengumpulan data menggunakan observasi, wawancara dan dokumentasi.

Dari hasil penelitian ini, dapat diambil kesimpulan bahwa  guru BK sangat berperan penting dalam membimbing dan memberi arahan untuk siswa memanajemen waktu. Tidak hanya guru BK, guru kelas dan orang tua juga dituntut untuk berperan aktif mengawasi dan membimbing siswa untuk memanajemen waktu dengan optimal dan produktif.
PENERAPAN LAYANAN BIMBINGAN KELOMPOK UNTUK MENGURANGI KASUS BULLYING SISWA KELAS VII SMP CERDAS MURNI TEMBUNG
Authors: Siregar Muftiha Ayunda
Published: August 2023

Penelitian ini berjudul, “Penerapan Layanan Bimbingan Kelompok Untuk Mengurangi Kasus Bullying Siswa Kelas VII SMP Cerdas Murni Tembung” yang dilatarbelakangi dengan banyaknya teridentifikasi kasus bullying di kalangan siswa sehingga perlu diatasi dengan penerapan layanan bimbingan konseling. Penerapan layanan bimbingan kelompok dilakukan sebagai upaya untuk mengurangi kasus bullying siswa terutama pada siswa SMP yang baru memasuki masa remaja yang penuh dengan gejolak. Metode penelitian ini adalah penelitian kualitatif dengan menggunakan pendekatakan deskriptif. Sumber data dalam penelitian ini adalah Kepala Sekolah, Guru BK, dan 4 Siswa kelas VII. Teknik pengumpulan data dalam penelitian ini adalah observasi, wawancara dan dokumentasi. Teknik analisis data dalam penelitian ini menggunakan Miles dan Huberman yaitu rduksi data, penyajian data dan verifikasi (menarik kesimpulan). Hasil penelitian yang telah diperoleh dari hasil observasi dan wawancara dapat disimpulkan bahwasanya : 1) Perilaku bullying yang ditemukan pada siswa kelas VII SMP Cerdas Murni seperti memukul, mendorong teman ketika sedang bermain, mengejek-ejek antarteman (menjelek-jelekkan), mengucapkan kata-kata yang kasar pada teman, dan sebagainya; 2) Penerapan layanan bimbingan kelompok untuk mengurangi kasus bullying siswa kelas VII SMP Cerdas Murni sudah terlaksana tetapi belum memadai karena tidak sering dilaksanakan maka dari itu guna mengurangi kasus bullying siswa guru BK harus meningkatkan pelaksanaan layanan bimbingan kelompok secara berkala dan meningkatkan pengadaan media bimbingan konseling seperti poster tentang bullying sebagai upaya lain guna mengatasi dan mengurangi kasus bullying yang terjadi.
PERAN LAYANAN INFORMASI DALAM MENGATASI STRES AKADEMIK SISWA DI MAS AL ASY’ARIYAH MEDAN KRIO
Authors: Tanjung Nadra Hasina
Published: August 2023

Latar Belakang Penelitian ini karena setiap siswa memiliki kemampuan dasar atau potensi yang sangat beragam. Dalam hal ini kaitannya dengan pelaksanaan layanan bimbingan konseling dalam mengatasi stree akademik yang dialami siswa dalam proses pembelajaran. Penelitian ini bertujuan untuk mendeskripsikan “upaya layanan informasi dalam mengatasi stres akademik siswa”. Dalam peneliti berusaha mengatasi stres akademik siswa dengan menggunakan layanan informasi. Jenis penelitian ini menggunakan pendekatan kualitatif dengan jenis penelitian tindakan bimbingan konseling (PTBK) dan menggunakan subyek yang disebut informan yaitu siswa di MAS Al Asy’ariyah Medan Krio. Adapun subjek penelitian ini menggunakan porposive sampel yaitu sampel yang diambil sesuai dengan tujuan penelitian. Berdasarkan penelitian yang dilaksanakan di MAS Al Asy’ariyah Medan Krio menunjukkan bahwa hasil penelitian menunjukkan adanya perubahan tingkat strees akademik ketika diberikan layanan informasi mengenai stress akdemik ini di MAS Al Asy’ariyah Medan Krio.
Use of Technology in Warehouse Operations
Authors:   Iqra University, Karachi, Pakistan, Khan Asad
Published: August 2023

The primary aim of this research is to examine how information technology impacts the efficiency of warehouse operations at a pharmaceutical supply agency. The study used a descriptive method and a cross-sectional study design. The participants were all professional staff members working in the stock and distribution directorate, and all of them were included in the study. The information technology tool employed in the study was found to enhance the performance of various warehouse operations, including inventory accuracy, picking accuracy, put-away accuracy, receiving time, order processing time, and warehouse space utilization. However, the study also revealed that the information technology implementation did not prevent theft and product leakage. Several challenges were identified, including frequent electric power interruptions, slow or unreliable internet connectivity, insufficient training and support for staff, and a lack of confidence among employees in using the information technology for effective warehouse operations management.
TRADUÇÃO: NOTAS PARA UM TRABALHO SOBRE A CATEGORIA DE JUSTIÇA
Authors: Benjamin Walter , Sousa Maykson Mardônio Cardoso de
Published: August 2023

As Notas para um trabalho sobre a categoria de justiça, aqui traduzidas diretamente do alemão “Notizen zu einer Arbeit über die Kategorie der Gerechtigkeit”, estiveram em posse de Gershom Scholem até sua morte, em 1982, razão pela qual mantiveram-se desconhecidas até virem à tona com a publicação de seus diários, ensaios e rascunhos, em 1995. Ainda em 1995, Rolf Tiedemman e Hermann Schweppenhäuser — organizadores dos Gesammelten Schriften de Walter Benjamin —, surpreendidos com este novo achado depois de já terem finalizado o trabalho dos GS no final dos anos 1980, trataram de publicá-la no quarto volume das Frankfurter Adorno Blätter, série de publicações dirigira por Rolf Tiedermann, na ocasião em que também era diretor do Adorno Archiv. Ali, foram publicadas juntamente com um comentário de Hermann Schweppenhäuser, intitulado “Benjamin, sobre a justiça: um achado nos diários de Scholem” [Benjamin über Gerechtigkeit: Ein Fund in Gerschom Scholems Tagebüchern]. As Notas podem ser consideradas o primeiro esforço de Benjamin para desenvolver uma reflexão sobre a categoria de justiça, e suas ressonâncias fazem-se sentir naquele que é considerado um dos ensaios mais importantes do autor a este respeito, Zur Kritik der Gewalt, colaborando sobremaneira para ampliar a discussão que também ali é empreendida: se neste último, Benjamin lança luz sobre um fundamento mítico do poder que lança mão da violência para garantir a sua manutenção; nas Notas, ele aponta para uma diferença substancial entre duas figuras jurídicas fundamentais para a sociedade burguesa: a posse e a propriedade. No texto, Benjamin estabelece que também a justiça é um bem, mas um bem que não pode ser possuído: a justiça, assim pensada, não diz respeito à regulação do direito de posse da pessoa (do proprietário), mas ao direito-de-bem do próprio bem.
A REALIDADE DA MEDIAÇÃO EMPRESARIAL E A SUA BAIXA ADESÃO NAS RELAÇÕES COORPORATIVAS NOS PEQUENOS E MÉDIOS CENTROS URBANOS
Authors: Souza Emanuel Vítor das Mercês , Alves Edmilson Junior
Published: August 2023

O presente versará sobre o estudo no tocante às resoluções conflituosas existentes nos centros comerciais, sobretudo os de pequeno e médio porte. Para que assim se amplie os perímetros de usualidade desse método, afim de almejar a recomposição nos ambientes de relações continuadas. Desta forma, discorrido através da explicação dos desafios da mediação empresarial nas relações colaborativas atuais; apresentação da efetividade das resoluções conflituosas, enfatizando os baixos custos para as empresas. Além destes, a ligação da mediação aos grandes e pequenos desafios das problemáticas perante os desafios. Para lograr êxito foi realizada uma pesquisa de campo com o intento de materializar a hipótese ora levantada, de que o mal que aflige a sociedade atual é a ignorância maciça. Logo essa hermenêutica da contemporaneidade, a longo prazo, tem ligação direta à pacificação social, uma vez que os litígios deslindam-se naturalmente devido ao fato de o Poder Judiciário não ser capaz de acompanhar o desenvolvimento das relações interpessoais e interempresariais. Vale ressaltar ainda que a Mediação Empresarial trata de forma direta uma das vertentes do desenvolvimento social nos pequenos e médios centros, haja vista que a economia local, na maioria das vezes é composta majoritariamente por micro e pequenos empreendedores, e nisso consiste a máxima da pertinência dessa temática, a fim de granjear a manutenção e quiçá o crescimento dos níveis de geração de emprego e renda, refletindo positivamente no Índice de Desenvolvimento Humano. Portanto esse trabalho é um convite à reta observância do real atendimento à função social dos processos judiciais, a eficácia, igualmente é perceptível perceber que a Mediação é instrumento utilizado a séculos, contudo, vindo a ter legislação especifica somente na contemporaneidade.
AFINAL, A VACINAÇÃO FOI UMA FORMA DE EFETIVAÇÃO DO PRINCÍPIO DA DIGNIDADE HUMANA?
Authors: Caldas Rebecca de Moura
Published: August 2023

O presente artigo explana como a vacinação pode ser uma forma de expressão do “princípio da dignidade humana”, com uma visão multidisciplinar, do conflito existente entre o direito à sáude e as liberdades individuais, com fulcro nas ações diretas de inconstitucionalidade (ADI’s) Nº 6.586 e 6.587 e o do Recurso Extraordinário com Agravo Nº 1.267.879. Assim, parte-se de uma qualificação referente ao direito à saúde como um direito coletivo e individual simultaneamente, em que a sua destinação é compromisso do Estado e do particular (indivíduo) para a real efetivação deste direito. Diante disso, é estabelecido uma conexão referente as liberdades individuais, sendo estas expressadas: pela autonomia do indivíduo sobre o corpo, em que esta autonomia se consubstancia na forma do “consentimento informado” e da “capacidade sanitária”, sendo estes fatores analisados diante do um ponto de vista “bioético”. Deste modo, perfaz afirmar, que a vacinação é a efetivação do direito a saúde e principalmente do direito à vida.
REINE GEWALT
Authors: Martins Ana Carolina , Paz Caio
Published: August 2023

Este artigo propõe realizar uma leitura do conceito de violência pura (reine gewalt) de Walter Benjamin. Essa leitura se caracteriza por um duplo movimento. Por um lado, ela exibe a crítica benjaminiana a respeito da conexão entre direito, violência e destino e, por outro, aponta elementos possíveis para um novo horizonte ético. Ao apresentar a crítica que o filósofo alemão elaborou no texto “Para uma crítica da violência”, articulamos as suas formulações não só com outros textos de “juventude”, produzidos mais ou menos na mesma época, mas também com textos tardios. Esse procedimento permitiu mostrar como a “ética dos meios puros” evocada pela reine gewalt interrompe o “destino” que a narrativa da tradição nos transmite a fim de garantir o vínculo entre poder e violência. Mais ainda, ele ajudou a exibir e deslocar a relação entre meios e fins, pensando em um meio puro como uma categoria ética fundamental. Com ela, foi possível articular violência pura e felicidade, porque ambas as categorias suspendem a relação com a finalidade, exibindo uma medialidade sem fim.
TEORIAS DO LUTO, FILOSOFIA DA HISTÓRIA
Authors: Zampieri Beatriz
Published: August 2023

O presente artigo procura formular a hipótese de uma filosofia política do luto no pensamento de Walter Benjamin, levando em consideração seus estudos sobre a tragédia nos escritos de juventude e, em particular, sua produção teórica da década de 1920. O argumento que fundamenta esta hipótese é que há certa especificidade inerente à teoria do trágico em Benjamin que excede a redução destes escritos a uma espécie de propedêutica teórica desconectada da totalidade de seu pensamento filosófico. Se, nos termos de Michel Löwy, há determinada “ruptura epistemológica” em sua filosofia, os elementos fundamentais deste momento de transição são anteriores aos escritos de 1930 e, sobretudo, à consolidação de suas Teses sobre o conceito de história. Existe na filosofia de Benjamin, afirmo, a partir da leitura de Birnbaum (2008), determinada incompletude inerente à concepção de tragédia e personagem trágico – ou do herói trágico – que reorienta e constitui uma noção muito particular de temporalidade, essencial à sua teoria da História. Esta incompletude pode ser chamada de tempo do luto – Trauerspiel, objeto de pesquisa de sua tese de habilitação sobre o barroco – e parece impregnar parte da produção teórica dessa época, especialmente no polêmico ensaio Para a crítica da violência. Escrito em 1921, este ensaio representa o momento de encontro fundamental de um pensamento engajado estética e politicamente com o próprio tempo. Benjamin atende à urgência de pensar sobre e através de seu tempo, ainda que com o risco de pensar uma forma inaugural ou, mesmo, perigosa, de estabelecer os limites para as manifestações particulares da violação da vida no direito. Os dois personagens lendários de Para a crítica da violência — Prometeu e Níobe — parecem apontar a esses registros particulares, bastante distintos, de violência. Assim, entre a esperança e o desespero, a tragédia oscila no pensamento benjaminiano e encontra, sob a figura do luto e da mãe enlutada, certa temporalidade que a vincula às representações barrocas. É preciso perguntar quem são essas personagens, quais as formas específicas à experiência de uma violência determinada que conclama as mulheres gregas – e não mais os heróis da Antiguidade Clássica – ao grito, rompendo com a injustiça no direito.
Caterina Valente, Wolfgang Lauth, Jazz und Schlager
Authors: Arndt Jürgen
Published: August 2023

Caterina Valente und Wolfgang Lauth, beide 1931 geboren, tragen in den 1950er Jahren jeweils markant zum Musikleben zwischen Jazz und Schlager bei. Von Mannheim, Ludwigshafen und Heidelberg ausgehend wirken Valente und Lauth in internationalen Verflechtungen, die insbesondere nach Paris und in die USA führen. Die Aktivitäten der Sängerin und Tänzerin bzw. des Pianisten und Komponisten eröffnen Einblicke in bis heute relevante Entwicklungen anhand bemerkenswerter Details und zum Teil überraschender Zusammenhänge. Dies versprechen schon die Titel der vier Hauptkapitel: 'Paris-Perspektiven', 'Lauth, Jazz und Alte Musik', 'Mit ›Valente-Reisen‹ unterwegs', 'Tanz in Revuefilm und Jazz-Ballett'. Zwar sind Caterina Valente und Wolfgang Lauth nie gemeinsam aufgetreten, doch gerade der Blick auf beide zusammen ergibt prägnante Einsichten in musikalische, mediale und gesellschaftliche Prozesse der Zeit. „ein Glücksfall der deutschen Jazzliteratur“, „ein spannend zu lesendes Buch, es sind hundert Bücher in einem“ (Siegfried Schmidt-Joos, Jazz Podium Mai 2022) „Arndts Buch lässt alte Glanzzeiten des Musiklebens der [Rhein-Neckar-]Region in neuer Pracht erstrahlen.“ (Georg Spindler, Mannheimer Morgen 30.11.2021)
Die digitale Transformation in der Managementberatung
Authors: Wehner Désirée
Published: August 2023

Digital transformation is a crucial success factor for the business model of management consulting firms. In general, realizing and valuing the internal benefits of digitization currently pose a significant challenge for many management consultancy firms. Efficiency, flexibility, and structure are currently considered the most significant impacts of digital transformation, while the actual consulting service plays a subordinate role. Désirée Wehner discusses the necessity of adapting the traditional consulting model and provides practical recommendations for leveraging the positive factors of digital transformation and managing the associated pressure for action.
Estimated Burden and Risk Factors of Ischemic and Hemorrhagic Strokes in a Tertiary Hospital, Mogadishu-Somalia: A Cross-Sectional Study
Authors: Sidow Nor Osman , Kög Nilüfer , Sheikh Hassan Mohamed , Tahlil Mohamud Mohamed Hayir
Published: August 2023

Objective: In Somalia, a country in East Africa, no data is available about key features of stroke such as incidence, prevalence, mortality, or stroke subtypes. The objective of this study is to show the burden of stroke, both ischemic and hemorrhagic stroke, and its risk factors in Somalia. Materials and Methods: We conducted a hospital-based retrospective study. Patients were recruited from January 1, 2019, to December 31, 2019, at the Mogadishu Somali Turkey Recep Tayyip Erdogan Training and Research Hospital. Results: A total of 292 participants with stroke (65.4% male and 34.6% women) were analyzed. The prevalence of ischemic and hemorrhagic strokes was 66.8% and 33.2%, respectively. A system for categorization of subtypes of ischemic stroke mainly based on etiology has been developed for the Trial of Org 10172 in Acute Stroke Treatment (TOAST). The most prevalent was a stroke of other determined etiology (28.7%), while the least common were lunar stroke (11.3%) and cardio-embolic (13.3%). The most prevalent hemorrhagic strokes were in the basal ganglia. Conclusions: In Somalia, there is no previous data on the prevalence and risk factors of stroke. We concluded that the prevalence of hemorrhagic stroke in Somalia is higher compared to other countries in the region.
Key words: Cardio-embolic, Basal ganglia, Computed tomography, Lacunar, Thalamus
A Social Phenomenology of Non-Player Characters (NPCs) in Videogames
Authors: Scriven Paul ,   Philosophy Documentation Center
Published: August 2023

Non-player characters (NPCs) are a common feature in contemporary videogames, particularly role-playing games (RPGs). Evidence suggests player relationships with these fictional, digital characters can manifest as deeply emotional experiences that can ‘bleed’ off the screen and affect the daily lives of players. However, research in this area is still in its infancy, and as yet has not been given a thorough conceptual treatment. Applying the sociological phenomenology of Alfred Schütz, this paper will examine the structure of the experiences that players have with NPCs, and how these experiences manifest as meaningful social experiences. By a reconceptualization of the player-NPC relationship as a deeply mediated human-human relationship, this paper aims to build a foundation for further phenomenological study into how players engage with fictional characters in immersive videogame worlds.
Motion Corrected Silent ZTE Neuroimaging
Authors: Ljungberg Emil , Wood Tobias , Solana Ana Beatriz , Williams Steven , Barker Gareth , Wiesinger Florian
Published: August 2023

We present a new method called MERLIN for motion corrected silent neuroimaging using zero echo time (ZTE) MRI. Self-navigation is achieved with an interleaved 3D spiral phyllotaxis trajectory to produce image navigators. Retrospective motion correction is then applied to the collected raw data. The acoustic noise of MELIN was less than 4 dBA above ambient levels. A range of different head motion paradigms were evaluated (rotation and nodding), showing greatly improved image quality after motion correction in all cases.
Diagnostic Accuracy of Spiral Whole-Heart Quantitative Adenosine Stress Cardiovascular Magnetic Resonance with Motion Compensated L1-SPIRIT
Authors: Pan Jonathan , Robinson Austin , Lozano Patricia Rodriguez , Yang Yang , McHugh Stephen , Holland Eric , Meyer Craig , Taylor Angela , Kramer Christopher , Salerno Michael
Published: August 2023

Variable density spiral (VDS) pulse sequences with motion compensated compressed sensing reconstruction allow for whole-heart quantitative assessment of myocardial perfusion but have not yet been clinically validated. In this study, we showed that whole-heart VDS stress perfusion has good diagnostic accuracy and ischemic burden evaluation. No significant difference was seen between visual and quantitative diagnostic performance and ischemic burden measurements.
Defining Normative Cerebral Hemodynamics in Cognitively Healthy Older Adults with 4D Flow MRI
Authors: Roberts Grant , Peret Anthony , Rivera-Rivera Leonardo , Cody Karly , Rowley Howard , Wieben Oliver , Johnson Sterling , Johnson Kevin , Eisenmenger Laura
Published: August 2023

It has been shown that vascular disease is strongly associated with Alzheimer’s disease (AD). It is thus important to establish normative cerebrovascular hemodynamics in aging populations. In this study, we comprehensively assess macrovascular hemodynamics using 4D flow MRI to obtain flow rates and pulsatility indices in 110 cognitively healthy, older adults and correlate these measures with age, sex, atherosclerotic cardiovascular disease (ASCVD) risk scores, and APOE genotypes. We found a (1) negative correlation between flow vs. age and flow vs. ASCVD, (2) a positive correlation between pulsatility vs. age and pulsatility vs. ASCVD, and (3) no correlations with APOE genotypes.
Wall shear stress and velocity pulsatility in the parent artery of an unruptured intracranial aneurysm - a 7T 4D flow MRI study.
Authors: van Tuijl Rick , Ruigrok Ynte , Timmins Kimberley , Velthuis Birgitta , van Ooij Pim , Zwanenburg Jaco , van der Schaaf Irene
Published: August 2023

The influence of maximum wall shear stress (WSSMAX) and velocity pulsatility (vPI) are extensively investigated in aortic aneurysms, but its influence along the Circle of Willis (CoW) in patients with unruptured intracranial aneurysms (UIA) is unknown. Thirteen patients with an UIA were scanned at 7T-MRI using 4D phase-contrast MRI, comparing hemodynamic parameters between the parent artery of the UIA and the corresponding contralateral artery. The parent vessel of the UIA showed significantly higher WSSMAX, blood-flow and velocity, and lower vPI compared to the unaffected contralateral side. This study supports a hemodynamic role in the aetiology of aneurysm formation.
Online FIRE Reconstruction of Cardiac MRF T1, T2 and ECV maps with Neural Network Dictionary Generation and Low-Rank Subspace Reconstruction
Authors: Fyrdahl Alexander , Seiberlich Nicole , Hamilton Jesse
Published: August 2023

The ability to reconstruct research images online may facilitate clinical translation and dissemination of new methods. Online implementations of cardiac MRF have been described previously, although they required long reconstruction times due to the need to perform online Bloch equation simulations. In this work, an efficient online 2D cardiac MRF reconstruction pipeline is introduced, capable of displaying myocardial tissue property maps in less than a minute.
Simultaneous gauging of liver fibrosis and inflammation using 3D single breath-hold Intenso MRE with the gravitational transducer.
Authors: Darwish Omar , Neji Radhouene , Jeljeli Sami , Metwalli Nader , Feeley Jenna , Rotman Yaron , Brown Rebecca , Ghany Marc , Kleiner David , Staeb Daniel , Speier Peter , Sinkus Ralph , Gharib Ahmed
Published: August 2023

Successful deployment of 3D liver MRE in the clinical assessment of fibrosis and inflammation requires a single breath-hold sequence to avoid geometric misalignment between different breath-holds and a phase-stable and efficient vibration for adequate wave penetration. We show initial data of Intenso MRE estimating the shear wave speed (Cs [m/s]) and the loss modulus (G’’ [kPa]). Both Cs and G’’ reflect a dependency on Ishak fibrosis and inflammation scores, respectively, in patients with chronic liver disease. In addition, we compare the magnitude of the shear modulus (|G*|) measured with Intenso and to the commonly utilized SE-EPI in such patients.
Free-breathing liver fat quantification with combined multi-echo Dixon and 3D radial stack-of-stars in children and adults at 3T and 1.5T
Authors: ZHANG Shuo , Nolte Teresa , Yoneyama Masami , Nebelung Sven , Kuhl Christiane , Barabasch Alexandra , Herrmann Jochen
Published: August 2023

Multi-echo gradient-echo Dixon based on the chemical shift method is currently the standard for non-invasive in vivo quantification of the liver fat but requires breath-holding. In young children or sick patients this is often challenging or not feasible. Despite recent attempts using different free-breathing approaches to mitigate patient motions, these are not widely available or routinely used. In this work we employ the multi-echo Dixon sequence with 3D pseudo-golden angle radial stack-of-stars readout for free-breathing liver fat assessment and report our initial results in children and adults at 3T and 1.5T with phantom validation and comparison to the standard method.
Intraprocedural MRI-based dosimetry during transarterial radioembolization with holmium-166 microspheres: a pilot study
Authors: Roosen Joey , Gotby Lovisa Westlund , Arntz Mark , Fütterer Jurgen , Janssen Marcel , van Wijk Meike , Overduin Christiaan , Nijsen J. Frank
Published: August 2023

Transarterial radioembolization (TARE) is a treatment for liver tumors based on injection of radioactive microspheres in the hepatic arteries under angiography guidance. Conventionally, there is no feedback on the dose distribution during treatment and dosimetry can only be evaluated after treatment. As holmium-166 microspheres used for TARE can be quantified with MRI, we investigated the feasibility and safety of performing TARE in a 3-T MRI in six patients. Multi-echo gradient echo imaging was performed at set time points during administration and provided intraprocedural insight into the microsphere distribution. Our findings may prove useful for providing a personalized approach to TARE.
Test-retest repeatability of data-driven radiomic features derived from a deep-learning model: Diffusion-weighted MRI of soft-tissue sarcoma
Authors: Mun Timothy Sum Hon , Thrussell Imogen , Winfield Jessica , Arthur Amani , Collins David , Koh Dow-Mu , Huang Paul , Doran Simon , Messiou Christina , Blackledge Matthew
Published: August 2023

Monitoring treatment response of soft-tissue sarcomas (STS) following radiotherapy is challenging due to the inherent intratumoral heterogeneity of the disease. Radiomics and deep-learning provide opportunities for the discovery of potent biomarkers of treatment response. Successful response biomarkers must demonstrate good baseline repeatability if they are to be used for personalized treatment. We explore the stability of radiomic features derived from a deep-learning pipeline by determining the pairwise correlation of derived features, and measuring the baseline repeatability of features derived from the Apparent Diffusion-Coefficient maps. We demonstrate that 81/512 features are both independent and stable at repeat baseline measurement.
High-fidelity submillimeter-isotropic-resolution diffusion MRI through gSlider-BUDA and circular EPI with S-LORAKS reconstruction
Authors: Liao Congyu , Yarach Uten , Cao Xiaozhi , Iyer Siddharth , Wang Nan , Kim Tae Hyung , Bilgic Berkin , Kerr Adam , Setsompop Kawin
Published: August 2023

BUDA-cEPI combines a circular-EPI (cEPI) trajectory with Blip-Up and Down Acquisition (BUDA), to achieve high-fidelity diffusion imaging. It employs full-ramp-sampling to efficiently cover a circular k-space to shorten the readout-train and mitigate T2*-blurring. For further readout-shortening, a combined phase-encoding(PE) & readout(RO) partial-Fourier (pF) is employed, where PE-pF is resolved via opposing the blip-up and down EPI-shots, and S-LORAKS reconstruction is used to effectively fill-out the remaining k-space. This resulted in an acquisition with markedly-reduced TE and ~40% reduced echo-train-length and T2*-blurring compared to standard-EPI at the same Rinplane and PE-pF. To achieve high-SNR, BUDA-cEPI is also combined with a gSlider-multi-slab acquisition.
Fast 3D acquisition of wave displacement in vivo for low-field MRE: application in the human forearm
Authors: Yushchenko Maksym , Sarracanie Mathieu , Salameh Najat
Published: August 2023

We describe a method to capture wave displacement in vivo in the human forearm for magnetic resonance elastography (MRE) at low magnetic field (0.1 T). Taking advantage of the inherently low spatial frequency nature of propagating waves, the proposed method samples a very low fraction (10%) of the 3D k-space, combined with efficient motion-encoding, processing schemes, and an optimized RF quadrature volume coil. For the first time, acquisitions are demonstrated in humans at a field below 1.5 T within only a few minutes (1-3 min).
Velocity-selective arterial spin labeling perfusion in the evaluation of treated high grade gliomas at 1.5 Tesla
Authors: Lambrecht Sebastian , Liu Dapeng , Dzaye Omar , Holdhoff Matthias , van Zijl Peter , Qin Qin , Lin Doris
Published: August 2023

Perfusion measures were compared between VSASL and DSC methods at 1.5T in 28 patients with treated high-grade glioma assigned into 2 groups: “tumor” (with detectable enhancing tumor, n=9) and “non-tumor” (without detectable tumor, n=19). All measures (rCBF and tSNR from VSASL, rCBV and rCBF from DSC) showed significant difference between “tumor” and “non-tumor” groups allowing reliable discrimination. In general, there was moderate to excellent agreement and correlation between these measures derived from VSASL vs. DSC. Hence, VSASL has potential to serve as a viable non-invasive alternative to DSC perfusion in the clinical disease surveillance without the need for exogenous contrast.
Exercise-induced hyperemia ASL and CrCEST at 3T demonstrate individual calf muscle improvement post-revascularization in patients with PAD
Authors: Sporkin Helen , Patel Toral , Betz Yaqub , Kramer Christopher , Meyer Craig
Published: August 2023

Peripheral arterial disease is a prevalent atherosclerotic disease characterized by atherosclerotic lesions in the limbs. Patients with PAD have been shown to have a delayed phosphocreatine recovery due to chronic ischemia. Patients with PAD may be candidates for revascularization, but outcomes are variable. CrCEST allows for creatine concentrations to be monitored at high spatial resolution, while ASL quantifies perfusion into tissue. We use this combination to revascularization in patients undergoing both endovascular and surgical procedures. Preliminary results link improvement in CrCEST decay curves and improved functional walk scores, while increased perfusion seen on ASL does not necessarily correlate with improvement.
Amyloid burden and vascular risk factors correlate with regional cerebral blood flow in a cognitively unimpaired population
Authors: Padrela Beatriz , Lorenzini Luigi , Collij Lyduine , Kate Mara ten , Braber Anouk den , Tomassen Jori , van Beckel Bart , Visser Pieter Jelle , Barkhof Frederik , Petr Jan , Mutsaerts Henk
Published: August 2023

Studying the association between cerebral blood flow (CBF), amyloid burden, and vascular risk factors in a cognitively unimpaired elderly population could clarify the role of CBF as a biomarker of cognitive decline. In 196 cognitively unimpaired participants, regional CBF was associated with regional amyloid-PET Centiloid. Vascular risk scores as measured by the Framingham risk score combined with amyloid Centiloid values were associated with increased CBF in vascular territories. Longitudinally, global CBF changes were associated with baseline precuneus amyloid burden.
Automatic background phase correction on 4D Flow using M-estimate SAmple Consensus (MSAC)
Authors: Fischer Carola , Wetzl Jens , Schäffter Tobias , Giese Daniel
Published: August 2023

4D Flow data requires background phase removal to correctly quantify flow velocities. Typical methods are semi-automatic, requiring manual parameter input and remain time-consuming. Furthermore, correction methods based on stationary tissue segmentation fail when in the presence of wrap-around artifacts. In contrast, the proposed M-Estimate SAmple Consensus (MSAC) algorithm robustly and fully automatically corrects background phases by rejecting pixels that show large deviations from the most probable phase offset fit. A parameter sensitivity analysis is proposed following in vivo application in 13 datasets.
Evidence for Improved Left Atrial Blood Flow Dynamics after Pulmonary Vein Isolation in Patients with Atrial Fibrillation
Authors: Pradella Maurice , Baraboo Justin , Gunasekaran Suvai , Collins Mitchell , Maroun Anthony , DiCarlo Amanda , Arora Rishi , Greenland Phil , Passman Rod , Markl Michael
Published: August 2023

Atrial fibrillation (AF) significantly increases stroke risk which is attributed to thrombus formation in the left atrium (LA) and to a greater extent the LA appendage (LAA). In this study, we investigated 4D-flow MRI-derived blood flow metrics from pre- and post-ablation exams in 26 AF patients undergoing pulmonary vein isolation (PVI). Blood stasis in both the LA and LAA significantly decreased in the post-PVI 4D-flow MRI. Furthermore, LA and LAA volumes also significantly decreased. Our results suggest that 4D-flow MRI was sensitive to detect treatment-related changes of LA and LAA flow metrics implicated on thromboembolic risk in AF patients.
In Vivo High Frame Rate Cartilage Strain During Knee Varus Combining Spiral DENSE MRI and Compressed Sensing
Authors: Lee Woowon , Miller Emily , Zhu Hongtian , Neu Corey
Published: August 2023

Displacement encoding with stimulated echoes (DENSE) MRI is used to calculate pixel-level deformation maps of soft tissues under repetitive motion. It is a powerful technique that can quantify the mechanical behavior of tissues from displacement. We apply spiral DENSE MRI on human knees and obtain multi-frame displacement and strain maps during varus loading, leading to compressive motion on the medial condyle. Since high SNR DENSE images require long scanning time which is costly and less tolerable for participants, we additionally apply compressed sensing (CS) to reduce the imaging time to less than five minutes.
Free-Breathing Liver QSM with High Isotropic Resolution Using Respiratory Motion-Resolved 3D Multi-Echo Cones MRI
Authors: Kang MungSoo , Jafari Ramin , Behr Gerald , Otazo Ricardo , Kee Youngwook
Published: August 2023

Liver quantitative susceptibility mapping (QSM) can provide a direct measurement of liver iron concentration (LIC). However, respiratory motion and rapid T2* decay are the major challenges in reliable liver QSM. To address these issues a motion-resolved multi-echo 3D cones MRI method with pseudo-random view ordering was implemented, which was then compared with a multi-echo Cartesian GRE sequence in a phantom and healthy volunteer. The proposed motion-resolved cones QSM presented strong motion-robustness in terms of image quality and ROI-based measurements in our phantom and in-vivo studies, demonstrating the feasibility of free-breathing liver QSM.
Microvascular invasion in patients with hepatocellular carcinoma: assessment with compression MR elastography
Authors: Pagé Gwenaël , Garteiser Philippe , Paradis Valérie , Sinkus Ralph , Vilgrain Valérie , Van Beers Bernard
Published: August 2023

The aim of this study was to investigate the value of compression MR elastography to assess microvascular invasion in hepatocellular carcinomas. MR elastographic and T2-weighted images were acquired at end expiration and end inspiration in 52 patients with hepatocellular carcinomas. The storage and loss moduli at inspiration did not differ between tumors with/without microvascular invasion. However, the compression stiffening rate, derived from the increase of tumor storage modulus between expiration and inspiration, had good diagnostic performance (area under the receiver operating characteristic curve 0.85) in detecting microvascular invasion.
Monitoring glucose uptake and metabolism in human kidney with dynamic 3D DMI at 7 T
Authors: Gursan Ayhan , Hendriks Arjan , Welting Dimitri , Klomp Dennis , Prompers Jeanine
Published: August 2023

Kidneys play a crucial role in glucose homeostasis via glucose reabsorption and glucose release into and glucose uptake from the circulation. We investigated the feasibility of measuring renal glucose uptake and metabolism with dynamic 3D DMI. A volunteer was scanned twice with two different ways of deuterated glucose administration: in the scanner and before scanning session. Similar glucose uptake was observed in the kidney and liver. We demonstrated the feasibility of measuring renal glucose uptake and metabolism with dynamic 3D DMI. This technique has potential to study the role of renal glucose uptake in glucose homeostasis in diabetes.
Observation of 2H labeled compounds in the human brain with 1H versus 2H magnetic resonance spectroscopy at 9.4T
Authors: Ruhm Loreen , Ziegs Theresia , Wright Andrew , Avdievich Nikolai , Henning Anke
Published: August 2023

The tracing of glucose metabolism is of interest in many pathologies of the human brain. In this abstract, we compare the information content of 2H MRSI detected deuterium metabolic imaging (DMI) to quantitative exchanged-labeled turnover 1H MRS (QELT), both measured at B0 = 9.4 Tesla. An uptake of 2H labeling was detectable for different metabolites for both methods. Consistent changes in 2H labeled Glx after the oral administration of [6,6’-2H2]-glucose were detected in the brain of healthy human subjects.
Neuronal Response to Transcranial Direct Current Stimulation (tDCS) in Multiple Sclerosis
Authors: Muccio Marco , Masters Lillian Walton , Pilloni Giuseppina , Krupp Lauren , Datta Abhishek , Bikson Marom , Charvet Leigh , Ge Yulin
Published: August 2023

Transcranial direct current stimulation (tDCS) represents an innovative therapeutic tool for neurological diseases such as multiple sclerosis (MS). In this study, MRI measurements of cerebral blood flow (CBF), venous oxygenation (Yv) and cerebral metabolic rate of oxygen (CMRO2) of MS patients and healthy controls (HCs) were acquired pre-, during- and post-tDCS to investigate its simultaneous effects. Whilst HCs showed an immediate increase (~5%) in CMRO2 (during- versus pre-tDCS, p<0.001), MS patients showed a delayed response to tDCS (7.7% CMRO2 increase pre- versus post-tDCS; p=0.007). We suggest that neuronal response to tDCS represents a potential biomarker of neuronal plasticity.
Longitudinal Changes of White Matter Hyperintensities Following Hemodialysis Initiation in Old Adults: A Prospective Pilot Study
Authors: Li Xiufeng , Metzger Gregory , Murray Anne
Published: August 2023

Repeated conventional hemodialysis may result in permanent cerebrovascular dysfunction that can initiate and exacerbate other cerebral structural abnormalities. Until today, the longitudinal WMH burden changes in old end-stage renal disease (ESRD) patients following the initiation of hemodialysis treatment have not been specifically studied. We performed a prospective pilot study with a hypothesis that WMH burden increases following the initiation of hemodialysis in old ESRD patient. Our study results suggested that WMH burdens increased significantly after the initiation of hemodialysis treatment.
Detection of Prostate Cancer using Diffusion-Relaxation Correlation Spectrum Imaging with Support Vector Machine Model – A Feasibility Study
Authors: Wei Xiaobin , Wu Guangyu , Xue Ke
Published: August 2023

For clinical prostate examination, magnetic resonance imaging (MRI) is a significant imaging modality. In this study, the feasibility of diffusion-relaxation correlation spectrum imaging (DR-CSI) combined with a support vector machine (SVM) model for detecting PCa in vivo was initially explored, and its diagnostic performance was evaluated and compared with the Prostate Imaging-Reporting and Data System (PI-RADS) score based on multiparametric MRI (MP-MRI). The DR-CSI combined with SVM model may suggest additional clinical value and potential to improve the detection of PCa.
Diffusion MRI and MRS probe cerebellar microstructure alterations in the rat developing brain during hepatic encephalopathy
Authors: Mosso Jessie , Rey Mickaël , Simicic Dunja , Pierzchala Katarzyna , Jelescu Ileana , Cudalbu Cristina
Published: August 2023

Children affected by hepatic encephalopathy (HE) suffer from irreversible cognitive damage, and thus exploring the developing brain during HE is of crucial interest. Histology in an adult rat model of HE suggested alterations in the cerebellar microstructure, but there is a need for in vivo probes of these changes. Combining diffusion MRS and diffusion MRI, we measured increased metabolites’ diffusivities, as well as an increased intra-neurite/axon water diffusivity in white and gray matter in the cerebellum of a young rat model of HE compared to control rats, suggesting an alteration of cell density and/or of neurite network complexity.
Longitudinal Brain and Cognitive Development of the First 1000 Days:A Large Multi-Cohort Multi-Scanner Study
Authors: Bruchhage Muriel , Chen Yaqing , Cataldo Alvaro Gajardo , Müller Hans-Georg , Weisee Elizabeth , Wilson Sian , Pietsch Maximilian , D'Sa Viren , Marquand Andre , Madhow Sylvia , Bouchard Kristofer , Cole James , Biondo Francesca , Elison Jed , OMuirchheartaigh Jonathan , Deoni Sean
Published: August 2023

The first 1000 days are essential for a child’s development, consisting of critical time windows for brain and cognitive development but also vulnerability. In this large multi-cohort study, we investigated typical development of 478 children with ≤6 timepoints across two different scanners with different acquisition protocols. PACE brain-for-age growth percentiles and regression slope functions with 95% pointwise confidence intervals identified critical windows of neurocognitive development. Our results could allow for more appropriate neurodevelopmental burden estimates across multi-scanner cohorts, and help identify primary risk factors and age-specific intervention impact.