bluuebunny/crossref_metadata_2025 huggingface dataset:
Modulatory Effects of Co-Fermented Pu-erh Tea with Aqueous Corn Silk Extract on Gut Microbes and Fecal Metabolites in Mice Fed High-Fat Diet
Authors: Ding Lin , Guan Hong , Yang Wenqing , Guo Hao , Zang Chuangang , Liu Yuchao , Ren Shan , Liu Jicheng
Published: August 2023

Pu-erh tea is recognized for its weight loss effects, but its potential association with gut microbiota and metabolites remains unclear. This research explored the alterations in gut flora and metabolite composition upon treatment with a co-fermented Pu-erh tea with an aqueous corn silk extract (CPC) in obese mice by employing integrated 16S ribosomal RNA gene sequencing and untargeted metabolomics processes. For 8 weeks, mice were fed control, high-fat, and high-fat diets which included a 46 mg/mL CPC extract. The CPC extract the alleviated high-fat diet (HFD), it stimulated systemic chronic inflammation, and it reduced the body weight, daily energy consumption, and adipose tissue weight of the mice. It also modified the gut microbiota composition and modulated the Lactobacillus, Bifidobacterium, Allobaculum, Turicibacter, and Rikenella genera. Fecal metabolomics analysis revealed that the CPC extract influenced the caffeine, cysteine, methionine, tryptophan, biotin metabolism pathways, primary bile acid, and steroid biosynthesis. This research revealed that the CPC extract could inhibit HFD-stimulated abnormal weight gain and adipose tissue accumulation in mice, and modulate mice gut microbiota composition and multiple metabolic pathways.
Probiotic OMNi-BiOTiC® 10 AAD Reduces Cyclophosphamide-Induced Inflammation and Adipose Tissue Wasting in Mice
Authors: Obermüller Beate , Singer Georg , Kienesberger Bernhard , Mittl Barbara , Stadlbauer Vanessa , Horvath Angela , Miekisch Wolfram , Fuchs Patricia , Schweiger Martina , Pajed Laura , Till Holger , Castellani Christoph
Published: August 2023

Cancer therapy is often associated with severe side effects such as drug induced weight loss, also known as chemotherapy-induced cachexia. The aim of this study was to investigate the effects of a multispecies probiotic (OMNi-BiOTiC® 10 AAD) in a chemotherapy mouse model. A total of 24 male BALB/c mice were gavage-fed with the probiotic formulation or water, once a day for 3 weeks. In the third week, the mice received intraperitoneal cyclophosphamide. At euthanasia, the organs were dissected, and serum was sampled for cytokine analysis. Tight junction components, myosin light chain kinase, mucins, and apoptosis markers were detected in the ileum and colon using histological analyses and qRT-PCR. Lipolysis was analyzed by enzymatic activity assay, Western blotting analyses, and qRT-PCR in WAT. The fecal microbiome was measured with 16S-rRNA gene sequencing from stool samples, and fecal volatile organic compounds analysis was performed using gas chromatography/mass spectrometry. The probiotic-fed mice exhibited significantly less body weight loss and adipose tissue wasting associated with a reduced CGI58 mediated lipolysis. They showed significantly fewer pro-inflammatory cytokines and lower gut permeability compared to animals fed without the probiotic. The colons of the probiotic-fed animals showed lower inflammation scores and less goblet cell loss. qRT-PCR revealed no differences in regards to tight junction components, mucins, or apoptosis markers. No differences in microbiome alpha diversity, but differences in beta diversity, were observed between the treatment groups. Taxonomic analysis showed that the probiotic group had a lower relative abundance of Odoribacter and Ruminococcus-UCG014 and a higher abundance of Desulfovibrio. VOC analysis yielded no significant differences. The results of this study indicate that oral administration of the multispecies probiotic OMNi-BiOTiC® 10 AAD could mitigate cyclophosphamide-induced chemotherapy side effects.
Lactiplantibacillus pentoses CCFM1227 Produces Desaminotyrosine to Protect against Influenza Virus H1N1 Infection through the Type I Interferon in Mice
Authors: Wang Qianwen , Fang Zhifeng , Xiao Yue , Wang Hongchao , Zhang Pinghu , Lu Wenwei , Zhang Hao , Zhou Xiuwen
Published: August 2023

Microbiota-derived desaminotyrosine (DAT) protects the host from influenza by modulating the type I interferon (IFN) response. The aim of this study was to investigate the antivirus effects of a DAT-producing bacteria strain. A comparative genomics analysis and UHPLC Q-Exactive MS were used to search for potential strains and confirm their ability to produce DAT, respectively. The anti-influenza functions of the DAT producer were evaluated using an antibiotic-treated mouse model by orally administering the specific strain before viral infection. The results showed the Lactiplantibacillus pentosus CCFM1227 contained the phy gene and produced DAT by degrading phloretin. In vivo, L. pentosus CCFM1227 re-inoculation increased the DAT level in feces, and protected from influenza through inhibiting viral replication and alleviating lung immunopathology. Furthermore, CCFM1227-derived DAT was positively correlated with the IFN-β level in the lung. The transcriptome results showed that CCFM1227 activated gene expression in the context of the defense response to the virus, and the response to interferon-beta. Moreover, CCFM1227 treatment upregulated the expression of MHC-I family genes, which regulate the adaptive immune response. In conclusion, L. pentosus CCFM1227 exerted antiviral effects by producing DAT in the gut, and this may provide a potential solution for creating effective antiviral probiotics.
Nutrition, Physical Activity and Supplementation in Irritable Bowel Syndrome
Authors: Radziszewska Marcelina , Smarkusz-Zarzecka Joanna , Ostrowska Lucyna
Published: August 2023

Irritable Bowel Syndrome (IBS) is a chronic, recurrent functional disorder of the intestine diagnosed based on the Rome IV criteria. Individuals suffering from IBS often associate the severity of their symptoms with the food they consume, leading them to limit the variety of foods they eat and seek information that could help them determine the appropriate selection of dietary items. Clear nutritional recommendations have not been established thus far. NICE recommends a rational approach to nutrition and, if necessary, the short-term implementation of a low FODMAP diet. Currently, the FODMAP diet holds the greatest significance among IBS patients, although it does not yield positive results for everyone affected. Other unconventional diets adopted by individuals with IBS lack supporting research on their effectiveness and may additionally lead to a deterioration in nutritional status, as they often eliminate foods with high nutritional value. The role of physical activity also raises questions, as previous studies have shown its beneficial effects on the physical and mental well-being of every individual, and it can further help alleviate symptoms among people with IBS. Supplementation can be a supportive element in therapy. Attention is drawn to the use of probiotics, vitamin D, and psyllium husk/ispaghula. This review aims to analyze the existing scientific research to determine the impact of various food items, physical activity, and dietary supplementation with specific components through dietary supplements on the course of IBS.
Dietary Models and Cardiovascular Risk Prevention in Pediatric Patients
Authors: Capra Maria , Monopoli Delia , Decarolis Nicola , Giudice Antonella , Stanyevic Brigida , Esposito Susanna , Biasucci Giacomo
Published: August 2023

Nutritional intervention is worldwide recognized as a first step treatment for subjects with increased cardiovascular risk and it is of utmost importance especially for children and adolescents. Currently scientific evidence supports the role of dietary patterns instead of simple single nutrients or foods in cardiovascular risk prevention. Indeed, the American Heart Association dietary guidelines have expanded beyond nutrients to dietary pattern, that comprise not only single food items but also behavioral or cultural habits of specific populations. The aim of our narrative review is to analyze the most frequently adopted dietary patterns in children and adolescents and to evaluate their effect on cardiovascular risk factors and in cardiovascular risk prevention. Literature review showed that children cannot be considered as little adults: nutritional intervention must always grant adequate growth and neurodevelopment before reaching the proposed goals, therefore dietary patterns considered heart-healthy for adult subjects might not be suitable for pediatric patients. Mediterranean diet, DASH diet, Nordic diet and some plant-based diets seem to be the most promising dietary patterns in terms of cardiovascular health in the developmental age, even if further studies are needed to better standardize and analyze their effect on growing up individuals.
Antioxidant Activity of Quercetin-Containing Liposomes-in-Gel and Its Effect on Prevention and Treatment of Cutaneous Eczema
Authors: Liu Chang , Cheng Xiaoman , Wu Yifang , Xu Weifang , Xia Hongmei , Jia Ruoyang , Liu Yinyin , Shen Si , Xu Yinxiang , Cheng Zhiqing
Published: August 2023

Cutaneous eczema is a kind of skin disease is characterized by inflammation. The main manifestations are various types of dermatitis, eczema, and urticaria. There are usually complications such as erythema, blisters, and epidermal peeling. The quercetin might have a therapeutic effect on cutaneous eczema due to its favorable antioxidant activity and anti-inflammatory effects. Currently, there are few studies on transdermal administration of antioxidant drugs for the treatment of cutaneous eczema. The aim of this study was to prepare quercetin-containing liposomes-in-gel (QU-LG), its antioxidant properties were evaluated, and it was used in the skin of mice suffering from dermal eczema to see if it had preventive and therapeutic effects in an attempt to make it a new option for the treatment of cutaneous eczema. QU-LG was prepared by the injection method to form the quercetin-containing liposomes (QU-L) and evenly dispersed in the natural dissolution of carboxymethylcellulose sodium (1%, CMC-Na). The release of QU-LG across the dialysis membranes was up to 30% and clearance of 1,1-diphenyl-2-picrylhydrazyl (DPPH) was 65.16 ± 3.513%. In anti-oxidation assay QU-LG inhibited malondialdehyde (MDA) production in liver better than the commercially available drug dexamethasone acetate cream. Compared with untreated mice, mice treated with QU-LG showed a statistically significant reduction in dermatopathologic symptoms. The results suggested that QU-LG had good antioxidant activity in vivo and in vitro and could be used for the prevention and treatment of cutaneous eczema.
Constructing ROS-Responsive Supramolecular Gel with Innate Antibacterial Properties
Authors: Zheng Fen , Du Wei , Yang Minggang , Liu Kaige , Zhang Shanming , Xu Long , Wen Yong
Published: August 2023

Bacterial infections, especially antibiotic-resistant bacterial infections, pose a significant threat to human health. Supramolecular gel with innate antibacterial properties is an advanced material for the treatment of bacterial infections, which have attracted great attention. Herein, a reactive oxygen species (ROS)-responsive innate antibacterial supramolecular gel is developed by a bottom-up approach based on phenylalanine and hydrazide with innate antibacterial properties. The structure of gelators and intermediate products was characterized by proton nuclear magnetic resonance (1H NMR) and a high-resolution mass spectrum (HRMS). The results of 1H NMR and the Fourier transform infrared spectrum (FT–IR) experiment disclosed that hydrogen bonding and the π–π stacking force are the important self-assembly driving forces of gelators. The microstructure and mechanical properties of gel were studied by Scanning electron microscope (SEM) and Rheometer, respectively. An in vitro degradation experiment proved that the gelator has ROS-responsive degradation properties. The in vitro drug release experiment further manifested that antibiotic-loaded gel has ROS-responsive drug-release performances. An in vitro cytotoxicity experiment showed that the supramolecular gel has good biocompatibility and could promote cell proliferation. The in vitro antibacterial experiment proved that the supramolecular gel has excellent inherent antibacterial properties, and the antibacterial rate against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) was 98.6% and 99.1%, respectively. The ROS-responsive supramolecular gel as a novel antibacterial agent has great application prospects in treating antibiotic-resistant bacterial-infected wounds and preventing the development of bacterial resistance.
Drug Repurposing to Circumvent Immune Checkpoint Inhibitor Resistance in Cancer Immunotherapy
Authors: To Kenneth K. W. , Cho William C.
Published: August 2023

Immune checkpoint inhibitors (ICI) have achieved unprecedented clinical success in cancer treatment. However, drug resistance to ICI therapy is a major hurdle that prevents cancer patients from responding to the treatment or having durable disease control. Drug repurposing refers to the application of clinically approved drugs, with characterized pharmacological properties and known adverse effect profiles, to new indications. It has also emerged as a promising strategy to overcome drug resistance. In this review, we summarized the latest research about drug repurposing to overcome ICI resistance. Repurposed drugs work by either exerting immunostimulatory activities or abolishing the immunosuppressive tumor microenvironment (TME). Compared to the de novo drug design strategy, they provide novel and affordable treatment options to enhance cancer immunotherapy that can be readily evaluated in the clinic. Biomarkers are exploited to identify the right patient population to benefit from the repurposed drugs and drug combinations. Phenotypic screening of chemical libraries has been conducted to search for T-cell-modifying drugs. Genomics and integrated bioinformatics analysis, artificial intelligence, machine and deep learning approaches are employed to identify novel modulators of the immunosuppressive TME.
Evaluation of Pharmacokinetic Feasibility of Febuxostat/L-pyroglutamic Acid Cocrystals in Rats and Mice
Authors: Yu Jeong-Eun , You Byoung Hoon , Bae Mingoo , Han Seung Yon , Jung Kiwon , Choi Young Hee
Published: August 2023

Febuxostat (FBX), a selective xanthine oxidase inhibitor, belongs to BCS class II, showing low solubility and high permeability with a moderate F value (<49%). Recently, FBX/L-pyroglutamic acid cocrystal (FBX-PG) was developed with an improving 4-fold increase of FBX solubility. Nevertheless, the in vivo pharmacokinetic properties of FBX-PG have not been evaluated yet. Therefore, the pharmacokinetic feasibility of FBX in FBX- and FBX-PG-treated rats and mice was compared in this study. The results showed that the bioavailability (F) values of FBX were 210% and 159% in FBX-PG-treated rats and mice, respectively. The 2.10-fold greater total area under the plasma concentration–time curve from time zero to infinity (AUC0-inf) of FBX was due to the increased absorption [i.e., 2.60-fold higher the first peak plasma concentration (Cmax,1) at 15 min] and entero-hepatic circulation of FBX [i.e., 1.68-fold higher the second peak plasma concentration (Cmax,2) at 600 min] in FBX-PG-treated rats compared to the FBX-treated rats. The 1.59-fold greater AUC0-inf of FBX was due to a 1.65-fold higher Cmax,1 at 5 min, and a 1.15-fold higher Cmax,2 at 720 min of FBX in FBX-PG-treated mice compared to those in FBX-treated mice. FBX was highly distributed in the liver, stomach, small intestine, and lungs in both groups of mice, and the FBX distributions to the liver and lungs were increased in FBX-PG-treated mice compared to FBX-treated mice. The results suggest the FBX-PG has a suitable pharmacokinetic profile of FBX for improving its oral F value.
Fault Detection and Location of 35 kV Single-Ended Radial Distribution Network Based on Traveling Wave Detection Method
Authors: Xu Xiaowei , Zhou Fangrong , Nie Yongjie , Xu Wenhua , Wang Ke , OuYang Jian , Zhou Kaihong , Chen Shan , Han Yiming
Published: August 2023

With the progress of society and the iterative improvement of infrastructure construction, the power grid transmission lines have also entered an era of intelligence. The national distribution system has made ensuring the regular operation of the distribution network as well as prompting troubleshooting and detection its top priority. Research on fault diagnosis for 35 kV single-ended radial distribution networks is still in its infancy compared to other hot topics in the industry, such as short-circuit fault detection and fault node localization. This study adopts the 35 kV single-ended radial distribution network as a model, detects fault lines via the traveling wave method, and accurately locates fault nodes using the wavelet conversion method, hoping to quickly identify and locate fault nodes in distribution networks. The experimental results demonstrate that the research method can quickly identify the faulty line and carry out further fault node location detection. The final obtained fault distance is 1.19 km with an actual error of only 0.16 km; the maximum relative errors are only 0.33 km and 0.21 km when the initial phase angle and transition resistance parameters are changed, respectively; and the error amplitude fluctuations are essentially stable. The experimental results also demonstrate that the research method can quickly identify the faulty line and carry out further fault node location.
Challenges of a Patient with Thromboembolism
Authors: Oancea Andra , Maștaleru Alexandra , Abdulan Irina Mihaela , Costache Alexandru Dan , Zota Mădălina Ioana , Negru Robert , Moisă Ștefana , Trandafir Laura Mihaela , Leon Maria Magdalena
Published: August 2023

Background: FV Leiden is an autosomal dominant disease, representing one of the most prevalent genetic causes for hereditary thrombophilia manifested by venous thromboembolism. Methods: We report a case of a 30-year-old patient who was admitted for enrollment in phase II cardiac rehabilitation. The cardiovascular disease onset was five years ago when the patient was diagnosed with superficial vein thrombosis, for which anticoagulant treatment was recommended. However, he discontinued the prescribed treatment independently, which resulted in the development of deep vein thrombosis. A screening for risk factors associated with venous thromboembolism was conducted, leading to the identification of a heterozygous mutation of factor V Leiden. Later, the patient was hospitalized for acute coronary syndrome necessitating stent implantation. Following this procedure, the patient started a cardiac rehabilitation program, where the patient received multidisciplinary counseling. Conclusions: At the end of the cardiac rehab, significant improvements were observed in clinical and hemodynamic parameters. Consequently, the patient was advised to continue rehabilitation treatment in the outpatient setting. Also, for patients with suboptimal maintenance of the therapeutic range of INR, the use of apixaban might be considered. Furthermore, the utilization of a reduced dosage of apixaban has demonstrated its effectiveness in preventing further venous thromboembolism.
Solid Precipitation and Visibility Measurements at the Centre for Atmospheric Research Experiments in Southern Ontario and Bratt’s Lake in Southern Saskatchewan
Authors: Boudala Faisal S. , Milbrandt Jason A.
Published: August 2023

Accurate measurement of solid precipitation (S) has a critical importance for proper understanding of the Earth’s hydrological cycle, validation of emerging technologies and weather prediction models, and developing parameterizations of severe weather elements such as visibility (Vis). However, measuring S is still a challenging problem, due mainly to wind effects. The wind effects are normally mitigated by using a Double-Fence Automated Reference (DFAR) system to reduce the wind speed (Ug). To contribute towards addressing some of these problems, we have analyzed datasets collected at two sites, Center for Atmospheric Research Experiments (CARE) and Bratt’s Lake, located in southern Ontario and southern Saskatchewan, Canada, respectively, using several instruments. The instruments at CARE include two Geonor gauges, one placed inside a DFAR (SDFAR) and the other inside a double Alter shield (DASG), a Pluvio2 gauge inside a single Alter shield (SASP), a HotPlate, a PARSIVEL2 disdrometer that measures S and fall velocity (V), and an FD12P senor that measures S and type and Vis. The instruments deployed in Bratt’s Lake includes a similar DFAR system and DAS Pluvio2 gauge. The results show that for the Ug observed in this study (Ug < 6 ms−1), both DASG and SASP have similar collection efficiency (CE) of near 70%. The transfer functions (TF) for DASG and SASP as a function of Ug and also Ug, and V were derived. The TF developed for the DASG that includes both Ug and V showed better agreement with observation than just Ug alone. The TF developed for DASG at CARE site was tested using the data collected in Bratt’s Lake and correlated well (R = 0.86), but slightly overestimated the S accumulation by about 12%. The S measured at CARE site using all the other instruments were correlated well with SDFAR (R = 0.9), but the PARSIVEL2 and FD12P overestimated and underestimated the snow amount, respectively, as compared the SDFAR. However, the HotPlate captured similar amount of S as the SDFAR. According to this study, the SDFAR showed good correlation with Vis.
A Cascade Network for Pattern Recognition Based on Radar Signal Characteristics in Noisy Environments
Authors: Xiong Jingwei , Pan Jifei , Du Mingyang
Published: August 2023

Target recognition mainly focuses on three approaches: optical-image-based, echo-detection-based, and passive signal-analysis-based methods. Among them, the passive signal-based method is closely integrated with practical applications due to its strong environmental adaptability. Based on passive radar signal analysis, we design an “end-to-end” model that cascades a noise estimation network with a recognition network to identify working modes in noisy environments. The noise estimation network is implemented based on U-Net, which adopts a method of feature extraction and reconstruction to adaptively estimate the noise mapping level of the sample, which can help the recognition network to reduce noise interference. Focusing on the characteristics of radar signals, the recognition network is realized based on the multi-scale convolutional attention network (MSCANet). Firstly, deep group convolution is used to isolate the channel interaction in the shallow network. Then, through the multi-scale convolution module, the finer-grained features of the signal are extracted without increasing the complexity of the model. Finally, the self-attention mechanism is used to suppress the influence of low-correlation and negative-correlation channels and spaces. This method overcomes the problem of the conventional method being seriously disturbed by noise. We validated the proposed method in 81 kinds of noise environment, achieving an average accuracy of 94.65%. Additionally, we discussed the performance of six machine learning algorithms and four deep learning algorithms. Compared to these methods, the proposed MSCANet achieved an accuracy improvement of approximately 17%. Our method demonstrates better generalization and robustness.
Comparative Study of the Atmospheric Gas Composition Detection Capabilities of FY-3D/HIRAS-I and FY-3E/HIRAS-II Based on Information Capacity
Authors: Xie Mengzhen , Gu Mingjian , Zhang Chunming , Hu Yong , Yang Tianhang , Huang Pengyu , Li Han
Published: August 2023

Fengyun-3E (FY-3E)/Hyperspectral Infrared Atmospheric Sounder-II (HIRAS-II) is an extension Fengyun-3D (FY-3D)/HIRAS-I. It is crucial to fully explore and analyze the detection capabilities of these two instruments for atmospheric gas composition. Based on the observed spectral data from the infrared hyperspectral detection instruments FY-3D/HIRAS-I and FY-3E/HIRAS-II, simulated radiance data and Jacobian matrices are obtained using the Rapid Radiative Transfer Model RTTOV (Radiative Transfer for TOVS (TIROS Operational Vertical Sounder)). By perturbing temperature (T), surface temperature (Tsurf), water vapor (H2O), ozone (O3), carbon dioxide (CO2), methane (CH4), carbon monoxide (CO), and nitrous oxide (N2O), the brightness temperature differences before and after the perturbations are calculated to analyze the sensitivity of temperature and various atmospheric gas components. The Improved Optimal Sensitivity Profile (OSP) algorithm is used to select the channels for atmospheric gas retrieval. The observation error covariance and background error covariance matrices are calculated, and then the information capacity is calculated, specifically the degrees of freedom for signal(DFS) and the entropy reduction (ER). Based on this, a comparative analysis is conducted on the information capacity of atmospheric water vapor and ozone components contained in the hyperspectral detection data from HIRAS-I and HIRAS-II instruments, respectively, to explore the retrieval capabilities of the two instruments for atmospheric gas components. We selected clear-sky data from the African oceanic region and the Chinese Yangtze River Delta terrestrial region for quantitative analysis of the information capacity of HIRAS-I and HIRAS-II. The results show that FY-3D/HIRAS-I and FY-3E/HIRAS-II exhibit different sensitivities to atmospheric gas components. In different experimental regions, temperature and water vapor show the most dramatic sensitivity changes, followed by ozone, methane, and nitrous oxide, while carbon monoxide and carbon dioxide exhibit the lowest variability. Regarding channel selection, HIRAS-II identifies more gas channels compared to HIRAS-I. The experiments concluded that HIRAS-II has a significantly higher information capacity than HIRAS-I, and the information capacity of atmospheric gas components varies across different experimental regions. Water vapor and ozone exhibit the highest information capacity, followed by nitrous oxide and methane, while carbon monoxide and carbon dioxide demonstrate the lowest capacity. The H2O ER (DFS) contained in FY-3E/HIRAS-II is 1.51 (0.35) higher than that in FY-3D/HIRAS-I, the O3 ER (DFS) in FY-3E/HIRAS-II is 1.51 (0.36) higher than that in FY-3D/HIRAS-I, while the N2O ER (DFS) in FY-3E/HIRAS-II is 0.17 (0.19) higher and the CH4 ER (DFS) is 0.07 (0.04) higher than that in FY-3D/HIRAS-I.
SeaMAE: Masked Pre-Training with Meteorological Satellite Imagery for Sea Fog Detection
Authors: Yan Haotian , Su Sundingkai , Wu Ming , Xu Mengqiu , Zuo Yihao , Zhang Chuang , Huang Bin
Published: August 2023

Sea fog detection (SFD) presents a significant challenge in the field of intelligent Earth observation, particularly in analyzing meteorological satellite imagery. Akin to various vision tasks, ImageNet pre-training is commonly used for pre-training SFD. However, in the context of multi-spectral meteorological satellite imagery, the initial step of deep learning has received limited attention. Recently, pre-training with Very High-Resolution (VHR) satellite imagery has gained increased popularity in remote-sensing vision tasks, showing the potential to replace ImageNet pre-training. However, it is worth noting that the meteorological satellite imagery applied in SFD, despite being an application of computer vision in remote sensing, differs greatly from VHR satellite imagery. To address the limitation of pre-training for SFD, this paper introduces a novel deep-learning paradigm to the meteorological domain driven by Masked Image Modeling (MIM). Our research reveals two key insights: (1) Pre-training with meteorological satellite imagery yields superior SFD performance compared to pre-training with nature imagery and VHR satellite imagery. (2) Incorporating the architectural characteristics of SFD models into a vanilla masked autoencoder (MAE) can augment the effectiveness of meteorological pre-training. To facilitate this research, we curate a pre-training dataset comprising 514,655 temporal multi-spectral meteorological satellite images, covering the Bohai Sea and Yellow Sea regions, which have the most sea fog occurrence. The longitude ranges from 115.00E to 128.75E, and the latitude ranges from 27.60N to 41.35N. Moreover, we introduce SeaMAE, a novel MAE that utilizes a Vision Transformer as the encoder and a convolutional hierarchical decoder, to learn meteorological representations. SeaMAE is pre-trained on this dataset and fine-tuned for SFD, resulting in state-of-the-art performance. For instance, using the ViT-Base as the backbone, SeaMAE pre-training which achieves 64.18% surpasses from-scratch learning, natural imagery pre-training, and VRH satellite imagery pre-training by 5.53%, 2.49%, and 2.21%, respectively, in terms of Intersection over Union of SFD.
Investigation of Turbulent Dissipation Rate Profiles from Two Radar Wind Profilers at Plateau and Plain Stations in the North China Plain
Authors: Yang Rongfang , Guo Jianping , Deng Weilong , Li Ning , Fan Junhong , Meng Deli , Liu Zheng , Sun Yuping , Zhang Guanglei , Liu Lihui
Published: August 2023

Turbulence is ubiquitous in the planetary boundary layer (PBL), which is of great importance to the prediction of weather and air quality. Nevertheless, the profiles of turbulence in the whole PBL as observed by radar wind profilers (RWPs) are rarely reported. In this communication, the purpose was to investigate the vertical structures of turbulence dissipation rate (ε) obtained from the Doppler spectrum width measurements from two RWPs at plateau (Zhangbei) and plain (Baoding) stations in the North China Plain for the year 2021, and to tease out the underlying mechanism for the difference of ε between Zhangbei and Baoding. Under clear-sky conditions, the annual mean value of ε in the PBL over the plateau station was found to be higher than that over the plain station throughout the daytime from 0900 to 1700 local standard time. The magnitude of ε at both stations showed significant seasonal variation, with the strongest ε in summer but the weakest in winter. If a larger difference between the 2 m air temperature and surface temperature (Ta−Ts), as a surrogate of sensible heat flux, is observed, the turbulence intensity tends to become stronger. The influence of vertical wind shear on turbulence was also analyzed. Comparison analyses showed that the plateau station of Zhangbei was characterized by larger sensible heat flux and stronger wind shear compared with the plain station of Baoding. This may account for the more intense ε within the PBL of Zhangbei. Moreover, the magnitude of ε in the PBL was positively correlated with the values of both Ta−Ts and vertical wind shear. The findings highlight the urgent need to characterize the vertical turbulence structure in the PBL over a variety of surfaces in China.
Electric Flight in Extreme and Uncertain Urban Environments
Authors: Wang Mingkai , Luiz Saulo O. D. , Zhang Shuguang , Lima Antonio M. N.
Published: August 2023

In a typical application scenario for electric aircraft, the emerging urban air mobility is faced with uncertain environmental conditions. To investigate the potential influence of uncertainties, this paper first develops comprehensive models of aircraft rigid body motion and electric propulsive performance. The urban environment model is built with emphasis on wind speed and the heat island effect. Thereafter, a flight guidance law augmented with nonlinear dynamic inversion is proposed to facilitate the performance evaluation of electric aircraft. Multiple simulations at various dates, times, and with different battery aging statuses are conducted. The results show that the battery aging effect and ambient temperature change are the most important factors that influence the aircraft performance. Suggestions to enhance the performance are given based on simulations.
Perception of Shared Electric Scooters: A Case Study from Poland
Authors: Turoń Katarzyna , Kubik Andrzej , Folęga Piotr , Chen Feng
Published: August 2023

Scooter-sharing services, that is, short-term rental of electric scooters, have been gaining popularity among last-mile transport solutions in recent years, winning both their supporters and opponents. Recognizing the different approaches of societies to scooters in the world, the objective of this work was to determine the perception of scooter-sharing services in Poland, that is, the fifth largest European market in terms of micromobility. The study was based on survey data conducted using the CAWI method among the points of active users of scooter-sharing systems. The article presents the results regarding the perception of electric scooters in terms of safety, use, operation, education, and elements of communication behavior. The results indicate that the respondents perceive the Polish market of sharing electric scooters well. They believe that riding a scooter is safe (despite pointing out numerous technical faults that may indicate insufficient technical knowledge about what they can mean for users), and they are against mobility hubs and disrupting free systems. Interestingly, respondents emphasize the need to modernize the regulations, the need for penalties for damage to vehicles, and the need to reduce fees. The results provide valuable clues on how to manage the new electric mobility. They also indicate a different approach of Polish users to the issue of perceiving scooters in relation to other European societies (such as France or Denmark), which is a valuable clue for modeling transport behavior.
Preferences and Expectations of Japanese Employees toward Telecommuting Frequency in the Post-Pandemic Era
Authors: Liang Jinjia , Miwa Tomio , Morikawa Takayuki
Published: August 2023

Telecommuting has reached unprecedented levels in Japan, previously established due to the sudden outbreak of the COVID-19 pandemic; however, there is a lack of in-depth research on telecommuting frequency from the perspective of the post-pandemic era. Hence, this study investigated the relationship between employees’ expected levels of telecommuting allowed by the company and their preferred telecommuting frequency after the pandemic using an ordered response probit model with a correlation effect. Data were collected through an online questionnaire in three major metropolitan areas of Japan; the questionnaire included questions on sociodemographic, commuting, household, and work-related characteristics. The findings revealed that work-environment characteristics are prime factors influencing both expected and preferred telecommuting frequency; therefore, a telecommuting-oriented work environment is crucial for bridging the gap between employees and employers regarding telecommuting. Also, the results indicated that the preferred level of telecommuting is unattainable probably due to a lack of support from the company. Finally, a gap was identified between the expected telecommuting frequency that companies would allow and the preferred telecommuting frequency. This study provides implementations to achieve a work environment better adapted to the post-pandemic era and contributes to the establishment of future traffic forecasting models that enable effective mobility management through telecommuting.
Enhancing Green Purchase Intentions: The Effects of Product Transformation Salience and Consumer Traceability Knowledge
Authors: Lin Jialing , Huang Yubo , Li Mengyao
Published: August 2023

Drawing on the literature on green innovation, recycling, digitalization, and human associative memory (HAM) theory, this study applies the concept of product transformation salience (PTS) to the context of green consumption, investigating how PTS affects consumer green purchase intention. This study also examines a mediating variable (perceived green brand coolness) and a moderating variable (consumer traceability knowledge) that are related to green innovation and green skepticism. Three experimental studies were used to test our proposed hypotheses. Our results demonstrate that presenting PTS leads to higher green purchasing intentions compared to conveying a general green message without PTS information. Furthermore, perceived green brand coolness partially mediates the relationship between PTS and purchase intention, indicating that PTS enhances brand coolness and purchase intention more strongly. Moreover, when consumer traceability knowledge is high, the presence of PTS leads to greater purchase intentions than when PTS is absent. Alternatively, when consumer traceability knowledge is low, a general green message increases green purchase intentions. Our findings have significant implications for successfully implementing green communication strategies and promoting green and digital transformation.
Study of Constitutive Models of Reconstituted Clay with High Initial Water Content
Authors: Liu Jie , Hu Shijun , Liu Gang , Zhang Jingbo , Lu Zheng
Published: August 2023

The compression and shear behavior of reconstituted clay are closely related to the initial water content of the reconstituted soil. It is difficult to obtain the compression and shear test data of clay with a high initial water content. This study aims to propose a model to predict the compression deformation and strength characteristics of reconstituted clay prepared with any initial water content using less data. Based on the concept of the disturbed state, this paper establishes a mathematical model that can simulate the compression and triaxial shear characteristics of reconstituted clay with different initial water contents. This model uses three compression curves of reconstituted clay with different initial water contents to calibrate the model parameters, and can predict the compression deformation characteristics of reconstituted clay prepared with any initial water content. The model can simulate the consolidated undrained shear behavior of clay reconstituted with different initial water contents. Comparing the measured data shows that the model is in good agreement with the measured compression curve and the triaxial stress–strain curve. The error of the predicted pore ratio and test pore ratio before yield is within 5%, and the error of the predicted pore ratio and test pore ratio after yield is within 10%. The stress–strain relationship of clay hardening with different water contents can be captured. The model can provide a preliminary prediction for the mechanical properties of clay with a high initial water content.
How Platform Economic Dependence Leads to Long Working Time: The Role of Work Pressure and Platform HRM Practices
Authors: Lin Xinqi , Lei Meng , Wang Xin
Published: August 2023

Drawing upon the conservation of resources (COR) theory, this paper discusses the effect of platform economic dependence on working time and the mediating role of work pressure, as well as the boundary role of platform human resource management practices, with a survey of 9576 takeaway riders. The results suggest that the greater the economic dependence of takeaway riders on the platform organization, the longer they work; work pressure plays a mediating role between platform economic dependence and working time; the amount of platform rewards has no effect on the positive relationship between platform economic dependence and working time, whereas the difficulty of obtaining platform rewards strengthens the positive relationship between platform economic dependence and working time. This paper contributes to the literature on gig work by providing a micro-individual perspective and to the literature on COR theory by enriching the studies of resource caravan passageways.
Higher Educational Institutions’ Digital Transformation and the Roles of Digital Platform Capability and Psychology in Innovation Performance after COVID-19
Authors: Du Rui , Grigorescu Adriana , Aivaz Kamer-Ainur
Published: August 2023

Digital technologies have transformed business models quickly, making sustainable, inventive performance essential for the survival of businesses, particularly in emerging markets. However, a lot of English educational institutions struggle to make use of digital platform capability (DPC) due to a lack of funding, resources, and experience that stifles prospects for advanced innovation. After the COVID-19 pandemic, this study suggests a framework to investigate how English educational institutions might improve their innovation performance using DPC. The study examines the relationship between digital innovation (DI) and innovation performance (IP), as well as the moderating effects of digital technology (DT). This study uses a quantitative methodology and questionnaire survey with 435 respondents from institutions that support DPC. The analysis examines the hypotheses using correlations, regression analyses, and 5000 bootstraps. The results demonstrate a positive relationship between DPC and IP, with DI acting as a mediator. Additionally, the outcomes show that the development of digital technology strengthens the positive influence of DPC on innovation performance. Through filling research gaps, this study adds to the body of knowledge. It also has significant management implications for English educational institutions looking to improve their innovation performance by fostering digital platform ability and digital innovation.
An Improved Two-Stage Spherical Harmonic ESPRIT-Type Algorithm
Authors: Zhou Haocheng , Liu Zhenghong , Luo Liyan , Wang Mei , Song Xiyu
Published: August 2023

Sensor arrays are gradually becoming a current research hotspot due to their flexible beam control, high signal gain, robustness against extreme interference, and high spatial resolution. Among them, spherical microphone arrays with complex rotational symmetry can capture more sound field information than planar arrays and can convert the collected multiple speech signals into the spherical harmonic domain for processing through spherical modal decomposition. The subspace class direction of arrival (DOA) estimation algorithm is sensitive to noise and reverberation, and its performance can be improved by introducing relative sound pressure and frequency-smoothing techniques. The introduction of the relative sound pressure can increase the difference between the eigenvalues corresponding to the signal subspace and the noise subspace, which is helpful to estimate the number of active sound sources. The eigenbeam estimation of signal parameters via the rotational invariance technique (EB-ESPRIT) is a well-known subspace-based algorithm for a spherical microphone array. The EB-ESPRIT cannot estimate the DOA when the elevation angle approaches 90°. Huang et al. proposed a two-step ESPRIT (TS-ESPRIT) algorithm to solve this problem. The TS-ESPRIT algorithm estimates the elevation and azimuth angles of the signal independently, so there is a problem with DOA parameter pairing. In this paper, the DOA parameter pairing problem of the TS-ESPRIT algorithm is solved by introducing generalized eigenvalue decomposition without increasing the computation of the algorithm. At the same time, the estimation of the elevation angle is given by the arctan function, which increases the estimation accuracy of the elevation angle of the algorithm. The robustness of the algorithm in a noisy environment is also enhanced by introducing the relative sound pressure into the algorithm. Finally, the simulation and field-testing results show that the proposed method not only solves the problem of DOA parameter pairing, but also outperforms the traditional methods in DOA estimation accuracy.
Stability Analysis of a Mathematical Model for Adolescent Idiopathic Scoliosis from the Perspective of Physical and Health Integration
Authors: Zhang Yuhua , Li Haiyin
Published: August 2023

In this paper, we take physical and health integration as the entry point. Firstly, based on the transformation mechanism of adolescent idiopathic scoliosis we construct a time delay differential model. Moreover, using the theory of characteristic equation we discuss the stability of a positive equilibrium under the delays of τ=0 and τ≠0. Furthermore, through numerical simulation, it has been verified the delay, τ, exceeds a critical value, the positive equilibrium loses its stability and Hopf bifurcation occurs. Lastly, we determine that sports have a positive effect on adolescent idiopathic scoliosis, directly reducing the number of people with adolescent idiopathic scoliosis.
Symmetry and the Nanoscale: Advances in Analytical Modeling in the Perspective of Holistic Unification
Authors: Di Sia Paolo
Published: August 2023

Analytical modeling presents symmetries and aesthetic-mathematical characteristics which are not catchable in numerical computation for science and technology; nanoscience plays a significant role in unification attempts, considering also models including holistic aspects of reality. In this paper we present new discovered results about the complete analytical quantum-relativistic form of the mean square deviation of position R2(t) related to a recently introduced Drude–Lorentz-like model (DS model), already performed at classical, quantum and relativistic level. The function R2(t) gives precise information about the distance crossed by carriers (electrons, ions, etc.) inside a nanostructure, considering both quantum effects and relativistic velocities. The model has a wide scale range of applicability; the nanoscale is considered in this paper, but it holds application from sub-pico-level to macro-level because of the existence of a gauge factor, making it applicable to every oscillating process in nature. Examples of application and suggestions supplement this paper, as well as interesting developments to be studied related to the model and to one of the basic elements of a current unified holistic approach based on vacuum energy.
Saturated Varieties of Semigroups
Authors: Nabi Muneer , Alali Amal S. , Bano Sakeena
Published: August 2023

The complete characterization of saturated varieties of semigroups remains an unsolved problem. The primary objective of this paper is to make significant progress in this direction. We initially demonstrate that the variety of semigroups defined by the identity axy=ayxa is saturated. The next main result establishes that the variety of semigroups determined by the identity axy=ayax is saturated. Finally, we show that medial semigroups satisfying the identity xy=xyn, where n≥2, are also saturated. These results collectively lead to the conclusion that epis from these saturated varieties are onto. This paper thus offers substantial progress towards the comprehensive characterization of saturated varieties of semigroups.