bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 1 from DLC1 Interaction with S100A10 Mediates Inhibition of In Vitro Cell Invasion and Tumorigenicity of Lung Cancer Cells through a RhoGAP-Independent Mechanism
Authors: Yang Xuyu , Popescu Nicholas C. , Zimonjic Drazen B.
Published: April 2023

Supplementary Figure 1 from DLC1 Interaction with S100A10 Mediates Inhibition of In Vitro Cell Invasion and Tumorigenicity of Lung Cancer Cells through a RhoGAP-Independent Mechanism
Supplementary Figure 3 from Hedgehog-Producing Cancer Cells Respond to and Require Autocrine Hedgehog Activity
Authors: Singh Samer , Wang Zhiqiang , Liang Fei Dennis , Black Kendall E. , Goetz John A. , Tokhunts Robert , Giambelli Camilla , Rodriguez-Blanco Jezabel , Long Jun , Lee Ethan , Briegel Karoline J. , Bejarano Pablo A. , Dmitrovsky Ethan , Capobianco Anthony J. , Robbins David J.
Published: April 2023

Supplementary Figure 3 from Hedgehog-Producing Cancer Cells Respond to and Require Autocrine Hedgehog Activity
Supplementary Figure 3 from LIN28B Promotes Colon Cancer Progression and Metastasis
Authors: King Catrina E. , Cuatrecasas Miriam , Castells Antoni , Sepulveda Antonia R. , Lee Ju-Seog , Rustgi Anil K.
Published: April 2023

Supplementary Figure 3 from LIN28B Promotes Colon Cancer Progression and Metastasis
Supplementary Figures 1-3 from MET-Independent Lung Cancer Cells Evading EGFR Kinase Inhibitors Are Therapeutically Susceptible to BH3 Mimetic Agents
Authors: Fan Weiwen , Tang Zhe , Yin Lihong , Morrison Bei , Hafez-Khayyata Said , Fu Pingfu , Huang Honglian , Bagai Rakesh , Jiang Shan , Kresak Adam , Howell Scott , Vasanji Amit , Flask Chris A. , Halmos Balazs , Koon Henry , Ma Patrick C.
Published: April 2023

Supplementary Figures 1-3 from MET-Independent Lung Cancer Cells Evading EGFR Kinase Inhibitors Are Therapeutically Susceptible to BH3 Mimetic Agents
Supplementary Figure 2 from Potent Antitumor Immunity Generated by a CD40-Targeted Adenoviral Vaccine
Authors: Hangalapura Basav N. , Oosterhoff Dinja , de Groot Jan , Boon Louis , Tüting Thomas , van den Eertwegh Alfons J. , Gerritsen Winald R. , van Beusechem Victor W. , Pereboev Alexander , Curiel David T. , Scheper Rik J. , de Gruijl Tanja D.
Published: April 2023

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Supplementary Figures 1-4, Tables 1-4, Methods from Coexpression of Oct4 and Nanog Enhances Malignancy in Lung Adenocarcinoma by Inducing Cancer Stem Cell–Like Properties and Epithelial–Mesenchymal Transdifferentiation
Authors: Chiou Shih-Hwa , Wang Mong-Lien , Chou Yu-Ting , Chen Chi-Jen , Hong Chun-Fu , Hsieh Wang-Ju , Chang Hsin-Tzu , Chen Ying-Shan , Lin Tzu-Wei , Hsu Han-Sui , Wu Cheng-Wen
Published: April 2023

Supplementary Figures 1-4, Tables 1-4, Methods from Coexpression of Oct4 and Nanog Enhances Malignancy in Lung Adenocarcinoma by Inducing Cancer Stem Cell–Like Properties and Epithelial–Mesenchymal Transdifferentiation
Supplementary Figure 2 from Vitamin D3 Enhances the Apoptotic Response of Epithelial Tumors to Aminolevulinate-Based Photodynamic Therapy
Authors: Anand Sanjay , Wilson Clara , Hasan Tayyaba , Maytin Edward V.
Published: April 2023

PDF file - 5169K, Morphology and TUNEL staining of A431 tumor regions post-PDT with or without Vit D preconditioning.
Supplementary Figure Legends 1-8 from Downregulation of c-MYC Protein Levels Contributes to Cancer Cell Survival under Dual Deficiency of Oxygen and Glucose
Authors: Okuyama Hiroaki , Endo Hiroko , Akashika Tamaki , Kato Kikuya , Inoue Masahiro
Published: April 2023

Supplementary Figure Legends 1-8 from Downregulation of c-MYC Protein Levels Contributes to Cancer Cell Survival under Dual Deficiency of Oxygen and Glucose
Supplementary Figures 1-7 from Human Solid Tumors Contain High Endothelial Venules: Association with T- and B-Lymphocyte Infiltration and Favorable Prognosis in Breast Cancer
Authors: Martinet Ludovic , Garrido Ignacio , Filleron Thomas , Le Guellec Sophie , Bellard Elisabeth , Fournie Jean-Jacques , Rochaix Philippe , Girard Jean-Philippe
Published: April 2023

PDF file, 440KB
Supplementary Figure 3 from Coexpression Network Analysis Identifies Transcriptional Modules Related to Proastrocytic Differentiation and Sprouty Signaling in Glioma
Authors: Ivliev Alexander E. , 't Hoen Peter A.C. , Sergeeva Marina G.
Published: April 2023

Supplementary Figure 3 from Coexpression Network Analysis Identifies Transcriptional Modules Related to Proastrocytic Differentiation and Sprouty Signaling in Glioma
Supplementary Discussion from Coexpression Network Analysis Identifies Transcriptional Modules Related to Proastrocytic Differentiation and Sprouty Signaling in Glioma
Authors: Ivliev Alexander E. , 't Hoen Peter A.C. , Sergeeva Marina G.
Published: April 2023

Supplementary Discussion from Coexpression Network Analysis Identifies Transcriptional Modules Related to Proastrocytic Differentiation and Sprouty Signaling in Glioma
Supplementary Video 3 from Integrated Optical Coherence Tomography and Microscopy for Ex Vivo Multiscale Evaluation of Human Breast Tissues
Authors: Zhou Chao , Cohen David W. , Wang Yihong , Lee Hsiang-Chieh , Mondelblatt Amy E. , Tsai Tsung-Han , Aguirre Aaron D. , Fujimoto James G. , Connolly James L.
Published: April 2023

Supplementary Video 3 from Integrated Optical Coherence Tomography and Microscopy for Ex Vivo Multiscale Evaluation of Human Breast Tissues
Supplementary Video 1 from Integrated Optical Coherence Tomography and Microscopy for Ex Vivo Multiscale Evaluation of Human Breast Tissues
Authors: Zhou Chao , Cohen David W. , Wang Yihong , Lee Hsiang-Chieh , Mondelblatt Amy E. , Tsai Tsung-Han , Aguirre Aaron D. , Fujimoto James G. , Connolly James L.
Published: April 2023

Supplementary Video 1 from Integrated Optical Coherence Tomography and Microscopy for Ex Vivo Multiscale Evaluation of Human Breast Tissues
Supplementary Heatmaps from Correlation of Somatic Mutation and Expression Identifies Genes Important in Human Glioblastoma Progression and Survival
Authors: Masica David L. , Karchin Rachel
Published: April 2023

Supplementary Heatmaps from Correlation of Somatic Mutation and Expression Identifies Genes Important in Human Glioblastoma Progression and Survival
Supplementary Figure 2 from FoxM1 in Tumorigenicity of the Neuroblastoma Cells and Renewal of the Neural Progenitors
Authors: Wang Zebin , Park Hyun Jung , Carr Janai R. , Chen Yi-ju , Zheng Yu , li Jing , Tyner Angela L. , Costa Robert H. , Bagchi Srilata , Raychaudhuri Pradip
Published: April 2023

Supplementary Figure 2 from FoxM1 in Tumorigenicity of the Neuroblastoma Cells and Renewal of the Neural Progenitors
Supplementary Figure 8 from Tumor-Evoked Regulatory B Cells Promote Breast Cancer Metastasis by Converting Resting CD4+ T Cells to T-Regulatory Cells
Authors: Olkhanud Purevdorj B. , Damdinsuren Bazarragchaa , Bodogai Monica , Gress Ronald E. , Sen Ranjan , Wejksza Katarzyna , Malchinkhuu Enkhzol , Wersto Robert P. , Biragyn Arya
Published: April 2023

Supplementary Figure 8 from Tumor-Evoked Regulatory B Cells Promote Breast Cancer Metastasis by Converting Resting CD4+ T Cells to T-Regulatory Cells
Supplementary Figure Legend from The Neuroblastoma-Associated F1174L ALK Mutation Causes Resistance to an ALK Kinase Inhibitor in ALK-Translocated Cancers
Authors: Sasaki Takaaki , Okuda Katsuhiro , Zheng Wei , Butrynski James , Capelletti Marzia , Wang Liping , Gray Nathanael S. , Wilner Keith , Christensen James G. , Demetri George , Shapiro Geoffrey I. , Rodig Scott J. , Eck Michael J. , Jänne Pasi A.
Published: April 2023

Supplementary Figure Legend from The Neuroblastoma-Associated F1174L ALK Mutation Causes Resistance to an ALK Kinase Inhibitor in ALK-Translocated Cancers
Supplementary Figure Legend from VEGFR-1 Expressed by Malignant Melanoma-Initiating Cells Is Required for Tumor Growth
Authors: Frank Natasha Y. , Schatton Tobias , Kim Soo , Zhan Qian , Wilson Brian J. , Ma Jie , Saab Karim R. , Osherov Veronika , Widlund Hans R. , Gasser Martin , Waaga-Gasser Ana-Maria , Kupper Thomas S. , Murphy George F. , Frank Markus H.
Published: April 2023

Supplementary Figure Legend from VEGFR-1 Expressed by Malignant Melanoma-Initiating Cells Is Required for Tumor Growth
Supplementary Figure Legends 1-3 from Phosphorylation of Carbonic Anhydrase IX Controls Its Ability to Mediate Extracellular Acidification in Hypoxic Tumors
Authors: Ditte Peter , Dequiedt Franck , Svastova Eliska , Hulikova Alzbeta , Ohradanova-Repic Anna , Zatovicova Miriam , Csaderova Lucia , Kopacek Juraj , Supuran Claudiu T. , Pastorekova Silvia , Pastorek Jaromir
Published: April 2023

PDf file - 72K
Supplementary Figures 1-9, Tables 1-2, Methods from Demethylation of RB Regulator MYPT1 by Histone Demethylase LSD1 Promotes Cell Cycle Progression in Cancer Cells
Authors: Cho Hyun-Soo , Suzuki Takehiro , Dohmae Naoshi , Hayami Shinya , Unoki Motoko , Yoshimatsu Masanori , Toyokawa Gouji , Takawa Masashi , Chen Taiping , Kurash Julia K. , Field Helen I. , Ponder Bruce A.J. , Nakamura Yusuke , Hamamoto Ryuji
Published: April 2023

Supplementary Figures 1-9, Tables 1-2, Methods from Demethylation of RB Regulator MYPT1 by Histone Demethylase LSD1 Promotes Cell Cycle Progression in Cancer Cells
Supplementary Figures 2-8 from Genome-Wide DNA Methylation Profiling of CpG Islands in Breast Cancer Identifies Novel Genes Associated with Tumorigenicity
Authors: Hill Victoria K. , Ricketts Christopher , Bieche Ivan , Vacher Sophie , Gentle Dean , Lewis Cheryl , Maher Eamonn R. , Latif Farida
Published: April 2023

Supplementary Figures 2-8 from Genome-Wide DNA Methylation Profiling of CpG Islands in Breast Cancer Identifies Novel Genes Associated with Tumorigenicity
Supplementary Video 2 from Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics
Authors: Orth James D. , Kohler Rainer H. , Foijer Floris , Sorger Peter K. , Weissleder Ralph , Mitchison Timothy J.
Published: April 2023

Supplementary Video 2 from Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics
Supplementary Figure 3 from LOXL2-Mediated Matrix Remodeling in Metastasis and Mammary Gland Involution
Authors: Barker Holly E. , Chang Joan , Cox Thomas R. , Lang Georgina , Bird Demelza , Nicolau Monica , Evans Holly R. , Gartland Alison , Erler Janine T.
Published: April 2023

Supplementary Figure 3 from LOXL2-Mediated Matrix Remodeling in Metastasis and Mammary Gland Involution
Supplementary Figure 3 from Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics
Authors: Orth James D. , Kohler Rainer H. , Foijer Floris , Sorger Peter K. , Weissleder Ralph , Mitchison Timothy J.
Published: April 2023

Supplementary Figure 3 from Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics
Supplementary Tables 1-2 from Thrombospondin-1 Triggers Cell Migration and Development of Advanced Prostate Tumors
Authors: Firlej Virginie , Mathieu Jacques R.R. , Gilbert Cristèle , Lemonnier Loïc , Nakhlé Jessica , Gallou-Kabani Catherine , Guarmit Basma , Morin Aurélie , Prevarskaya Natalia , Delongchamps Nicolas Barry , Cabon Florence
Published: April 2023

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Supplementary Figure 4 from The RASSF3 Candidate Tumor Suppressor Induces Apoptosis and G1–S Cell-Cycle Arrest via p53
Authors: Kudo Takumi , Ikeda Mitsunobu , Nishikawa Misa , Yang Zeyu , Ohno Kikuo , Nakagawa Kentaro , Hata Yutaka
Published: April 2023

PDF file - 135K, This figure demonstrates that RASSF3 interacts with MST2 but that RASSF3-induced apoptosis in HCT116 cells is independent of the Hippo pathway but is dependent on MOAP1
Supplementary Figure 1 from Cell-Cycle Regulator Cks1 Promotes Hepatocellular Carcinoma by Supporting NF-κB–Dependent Expression of Interleukin-8
Authors: Lee Eun-Kyoung , Kim Dae-Ghon , Kim Jang-Seong , Yoon Yeup
Published: April 2023

PDF file - 80K
Supplementary Figure 1 from The RASSF3 Candidate Tumor Suppressor Induces Apoptosis and G1–S Cell-Cycle Arrest via p53
Authors: Kudo Takumi , Ikeda Mitsunobu , Nishikawa Misa , Yang Zeyu , Ohno Kikuo , Nakagawa Kentaro , Hata Yutaka
Published: April 2023

PDF file - 295K, This figure demonstrates that RASSF3 induces apoptosis in HeLa cells
Supplementary Figure Legends 1-9 from A Zebrafish Model to Study and Therapeutically Manipulate Hypoxia Signaling in Tumorigenesis
Authors: Santhakumar Kirankumar , Judson Emma C. , Elks Philip M. , McKee Sarah , Elworthy Stone , van Rooijen Ellen , Walmsley Sarah S. , Renshaw Stephen A. , Cross Simon S. , van Eeden Fredericus J.M.
Published: April 2023

PDF file - 438K
Supplementary Figure Legends 1-5 from TRPM7 Is Required for Breast Tumor Cell Metastasis
Authors: Middelbeek Jeroen , Kuipers Arthur J. , Henneman Linda , Visser Daan , Eidhof Ilse , van Horssen Remco , Wieringa Bé , Canisius Sander V. , Zwart Wilbert , Wessels Lodewyk F. , Sweep Fred C.G.J. , Bult Peter , Span Paul N. , van Leeuwen Frank N. , Jalink Kees
Published: April 2023

PDF file - 96K
Supplementary Figure 3 from TRPM7 Is Required for Breast Tumor Cell Metastasis
Authors: Middelbeek Jeroen , Kuipers Arthur J. , Henneman Linda , Visser Daan , Eidhof Ilse , van Horssen Remco , Wieringa Bé , Canisius Sander V. , Zwart Wilbert , Wessels Lodewyk F. , Sweep Fred C.G.J. , Bult Peter , Span Paul N. , van Leeuwen Frank N. , Jalink Kees
Published: April 2023

PDF file - 54K, TRPM7 shRNA#2 treatment reduces malignant phenotype of MDA-MB-231 cells
Supplementary Figure 2 from TRPM7 Is Required for Breast Tumor Cell Metastasis
Authors: Middelbeek Jeroen , Kuipers Arthur J. , Henneman Linda , Visser Daan , Eidhof Ilse , van Horssen Remco , Wieringa Bé , Canisius Sander V. , Zwart Wilbert , Wessels Lodewyk F. , Sweep Fred C.G.J. , Bult Peter , Span Paul N. , van Leeuwen Frank N. , Jalink Kees
Published: April 2023

PDF file - 3.9MB, TRPM7 knockdown does not affect MDA-MB-231 cell proliferation but impairs metastasis formation in vivo
Supplementary Figure 4 from Mre11-Dependent Degradation of Stalled DNA Replication Forks Is Prevented by BRCA2 and PARP1
Authors: Ying Songmin , Hamdy Freddie C. , Helleday Thomas
Published: April 2023

PDF file - 34K, Reduction of ssDNA by inhibition of Mre11
Supplementary Figure 2 from Mre11-Dependent Degradation of Stalled DNA Replication Forks Is Prevented by BRCA2 and PARP1
Authors: Ying Songmin , Hamdy Freddie C. , Helleday Thomas
Published: April 2023

PDF file - 34K, Mre11 foci formation in BRCA2 deficient cells is independent of NHEJ
Supplementary Figure 2 from Estrogen Promotes ER-Negative Tumor Growth and Angiogenesis through Mobilization of Bone Marrow–Derived Monocytes
Authors: Iyer Vandana , Klebba Ina , McCready Jessica , Arendt Lisa M. , Betancur-Boissel Monica , Wu Meng-Fen , Zhang Xiaomei , Lewis Michael T. , Kuperwasser Charlotte
Published: April 2023

PDF file - 43K, Characterization of GFP+ BMDCs recruited to matrigel plugs in response to estrogen
Supplementary Figure Legends 1-3, Methods from Chronic Autophagy Is a Cellular Adaptation to Tumor Acidic pH Microenvironments
Authors: Wojtkowiak Jonathan W. , Rothberg Jennifer M. , Kumar Virendra , Schramm Karla J. , Haller Edward , Proemsey Joshua B. , Lloyd Mark C. , Sloane Bonnie F. , Gillies Robert J.
Published: April 2023

PDF file - 103K
Supplementary Methods and Materials from ZNF217 Is a Marker of Poor Prognosis in Breast Cancer That Drives Epithelial–Mesenchymal Transition and Invasion
Authors: Vendrell Julie A. , Thollet Aurélie , Nguyen Nhan T. , Ghayad Sandra E. , Vinot Stéphanie , Bièche Ivan , Grisard Evelyne , Josserand Véronique , Coll Jean-Luc , Roux Pierre , Corbo Laura , Treilleux Isabelle , Rimokh Ruth , Cohen Pascale A.
Published: April 2023

PDF file - 107K, complementary information and methods on breast-tumor cohorts, HMLE cells and transcriptomic analysis
Supplementary Figure 2 from Global Quantitative Phosphoproteome Analysis of Human Tumor Xenografts Treated with a CD44 Antagonist
Authors: Weigand Stefan , Herting Frank , Maisel Daniela , Nopora Adam , Voss Edgar , Schaab Christoph , Klammer Martin , Tebbe Andreas
Published: April 2023

PDF file - 269K, Effect of RG7356 on p-MEK1/2 signal in MDA-MB 231 xenografts
Supplementary Figure 3 from TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression
Authors: Duvvuri Umamaheswar , Shiwarski Daniel J. , Xiao Dong , Bertrand Carol , Huang Xin , Edinger Robert S. , Rock Jason R. , Harfe Brian D. , Henson Brian J. , Kunzelmann Karl , Schreiber Rainer , Seethala Raja S. , Egloff Ann Marie , Chen Xing , Lui Vivian W. , Grandis Jennifer R. , Gollin Susanne M.
Published: April 2023

PDF file - 97K, TMEM16A manipulation via shRNA mediated knock-down or overexpression leads to a measurable change in chloride conductance. Quantitative PCR demonstrates a significant decrease (~75%) in TMEM16A levels after shRNA treatment (A; mean � SEM; n=3, ***P<0.001). T24 cells stably overexpressing TMEM16A demonstrate elevated gene expression by qPCR (B; mean � SEM; n=3, ***P<0.001). MQAE assays were used to demonstrate chloride fluxes in T24 cells treated with shRNA or cDNA expressing TMEM16A (C, D & E; mean � SEM; n=3, ***P<0.001). TMEM16A knock-down leads to a ~50% decrease in chloride-flux associated fluorescence. A comparison of the chloride fluxes for the TMEM16A overexpressing and shRNA knock-down cells to control demonstrates the relative differences in chloride channel activity over time (E). Evaluation of the TMEM16A-K610A mutant shows reduced channel activity when transfected into HEK-293T cells (mean � SEM; *P<0.05). HEK-293T cells were transfected with the indicated plasmids. Chloride conductance was evaluated by patch clamping. The TMEM16A-K610A mutant demonstrates ~20% of the activity of wild-type protein, suggesting that it functions as a hypomorphic version of the protein (F).
Supplementary Table 3 from Biomarkers of HPV in Head and Neck Squamous Cell Carcinoma
Authors: Liang Caihua , Marsit Carmen J. , McClean Michael D. , Nelson Heather H. , Christensen Brock C. , Haddad Robert I. , Clark John R. , Wein Richard O. , Grillone Gregory A. , Houseman E. Andres , Halec Gordana , Waterboer Tim , Pawlita Michael , Krane Jeffrey F. , Kelsey Karl T.
Published: April 2023

PDF file - 63K, The association between selected markers and overall survival of HNSSC patients stratified by tumor sites, Eastern Massachusetts, 1999-2003
Supplementary Table 8 from Multilevel Whole-Genome Analysis Reveals Candidate Biomarkers in Clear Cell Renal Cell Carcinoma
Authors: Girgis Andrew H. , Iakovlev Vladimir V. , Beheshti Ben , Bayani Jane , Squire Jeremy A. , Bui Anna , Mankaruos Marina , Youssef Youssef , Khalil Bishoy , Khella Heba , Pasic Maria , Yousef George M.
Published: April 2023

PDF file - 34K, Significantly expressed proteins encoded by genes in regions that are cytogenetically associated with copy-number aberrations in aberrant versus diploid tumors
Supplementary Figure 1 from Biomarkers of HPV in Head and Neck Squamous Cell Carcinoma
Authors: Liang Caihua , Marsit Carmen J. , McClean Michael D. , Nelson Heather H. , Christensen Brock C. , Haddad Robert I. , Clark John R. , Wein Richard O. , Grillone Gregory A. , Houseman E. Andres , Halec Gordana , Waterboer Tim , Pawlita Michael , Krane Jeffrey F. , Kelsey Karl T.
Published: April 2023

PDF file - 35K, ROC curves for HPV assays. AUC=Area under the Curve. P=0.024 from the DeLong's tests comprising the AUCs of E7 and DNA (MPG); P=0.05 comparing the AUCs of E7 and L1 (MS)
Supplementary Video 4 from Tumor Cell–Derived Angiopoietin-like Protein ANGPTL2 Is a Critical Driver of Metastasis
Authors: Endo Motoyoshi , Nakano Masahiro , Kadomatsu Tsuyoshi , Fukuhara Shigetomo , Kuroda Hiroaki , Mikami Shuji , Hato Tai , Aoi Jun , Horiguchi Haruki , Miyata Keishi , Odagiri Haruki , Masuda Tetsuro , Harada Masahiko , Horio Hirotoshi , Hishima Tsunekazu , Nomori Hiroaki , Ito Takaaki , Yamamoto Yutaka , Minami Takashi , Okada Seiji , Takahashi Takashi , Mochizuki Naoki , Iwase Hirotaka , Oike Yuichi
Published: April 2023

AVI file - 1.5MB
Supplementary Video 1 from Tumor Cell–Derived Angiopoietin-like Protein ANGPTL2 Is a Critical Driver of Metastasis
Authors: Endo Motoyoshi , Nakano Masahiro , Kadomatsu Tsuyoshi , Fukuhara Shigetomo , Kuroda Hiroaki , Mikami Shuji , Hato Tai , Aoi Jun , Horiguchi Haruki , Miyata Keishi , Odagiri Haruki , Masuda Tetsuro , Harada Masahiko , Horio Hirotoshi , Hishima Tsunekazu , Nomori Hiroaki , Ito Takaaki , Yamamoto Yutaka , Minami Takashi , Okada Seiji , Takahashi Takashi , Mochizuki Naoki , Iwase Hirotaka , Oike Yuichi
Published: April 2023

AVI file - 6.8MB
Supplementary Figure 8 from Raf Kinase Inhibitor RKIP Inhibits MDA-9/Syntenin-Mediated Metastasis in Melanoma
Authors: Das Swadesh K. , Bhutia Sujit K. , Sokhi Upneet K. , Azab Belal , Su Zhao-zhong , Boukerche Habib , Anwar Talha , Moen Erika L. , Chatterjee Devasis , Pellecchia Maurizio , Sarkar Devanand , Fisher Paul B.
Published: April 2023

PDF file - 180K, Effect of RKIP expression on B-RAF mutant cells
Supplementary Table 1 from Effective Treatment of Metastatic Forms of Epstein-Barr Virus–Associated Nasopharyngeal Carcinoma with a Novel Adenovirus-Based Adoptive Immunotherapy
Authors: Smith Corey , Tsang Janice , Beagley Leone , Chua Daniel , Lee Victor , Li Vivian , Moss Denis J. , Coman William , Chan Kwok H. , Nicholls John , Kwong Dora , Khanna Rajiv
Published: April 2023

PDF file - 41K
Supplementary Figure 4 from Perturbation of Rb, p53, and Brca1 or Brca2 Cooperate in Inducing Metastatic Serous Epithelial Ovarian Cancer
Authors: Szabova Ludmila , Yin Chaoying , Bupp Sujata , Guerin Theresa M. , Schlomer Jerome J. , Householder Deborah B. , Baran Maureen L. , Yi Ming , Song Yurong , Sun Wenping , McDunn Jonathan E. , Martin Philip L. , Van Dyke Terry , Difilippantonio Simone
Published: April 2023

PDF file - 325K, Nuclear p53 expression correlates positively with loss of wild type allele in serous epithelial ovarian carcinomas in p53m/+ mutant mice
Supplementary Figure 2 from Viral RNA Patterns and High Viral Load Reliably Define Oropharynx Carcinomas with Active HPV16 Involvement
Authors: Holzinger Dana , Schmitt Markus , Dyckhoff Gerhard , Benner Axel , Pawlita Michael , Bosch Franz X.
Published: April 2023

PDF file - 100K, Area under the time-dependent receiver operating characteristic (ROC) curves for overall and progression-free survival over 5 years follow-up. Curves are based on the clinical model (black) together with the viral markers (HPV16 DNA (red), viral load (green), HPV16 E6* RNA (blue), HPV16 CxCa-like RNA patterns (turquois) and HPV marker combination (purple)), with the cellular marker p16INK4a (yellow) or with the combination of p16INK4a and HPV16 DNA (gray). The horizontal line at 0.5 is included for reference corresponding to random guessing.
Supplementary Figure 1 from Potent Induction of Tumor Immunity by Combining Tumor Cryoablation with Anti–CTLA-4 Therapy
Authors: Waitz Rebecca , Solomon Stephen B. , Petre Elena N. , Trumble Anne E. , Fassò Marcella , Norton Larry , Allison James P.
Published: April 2023

PDf file - 198K
Supplementary Figure 3 from BRAF Inhibitor Vemurafenib Improves the Antitumor Activity of Adoptive Cell Immunotherapy
Authors: Koya Richard C. , Mok Stephen , Otte Nicholas , Blacketor Kevin J. , Comin-Anduix Begonya , Tumeh Paul C. , Minasyan Aspram , Graham Nicholas A. , Graeber Thomas G. , Chodon Thinle , Ribas Antoni
Published: April 2023

PDF file - 109K, Effects of vemurafenib on the systemic distribution of adoptively transferred pmel-1 splenocytes
Supplementary Figure 1 from Identification of an Epigenetic Profile Classifier That Is Associated with Survival in Head and Neck Cancer
Authors: Poage Graham M. , Butler Rondi A. , Houseman E. Andrés , McClean Michael D. , Nelson Heather H. , Christensen Brock C. , Marsit Carmen J. , Kelsey Karl T.
Published: April 2023

PDF file - 51K, Frequency histogram outlining the methylation characteristics of the study population
Supplementary Table 3 from Resistance to Selective BRAF Inhibition Can Be Mediated by Modest Upstream Pathway Activation
Authors: Su Fei , Bradley William D. , Wang Qiongqing , Yang Hong , Xu Lizhong , Higgins Brian , Kolinsky Kenneth , Packman Kathryn , Kim Min Jung , Trunzer Kerstin , Lee Richard J. , Schostack Kathleen , Carter Jade , Albert Thomas , Germer Soren , Rosinski Jim , Martin Mitchell , Simcox Mary Ellen , Lestini Brian , Heimbrook David , Bollag Gideon
Published: April 2023

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Supplementary Video 2 from Basal but not Luminal Mammary Epithelial Cells Require PI3K/mTOR Signaling for Ras-Driven Overgrowth
Authors: Plichta Kristin A. , Mathers Jessica L. , Gestl Shelley A. , Glick Adam B. , Gunther Edward J.
Published: April 2023

MOV file - 2.1MB, Live cell imaging of an MMTV-rtTA/TGFP organoids. Representative video depicting an organoid prepared from a Dox-naive luminalGFP (MMTV-rtTA/TGFP) mouse cultured in 3D with Dox
Supplementary Figures 1 - 8 from β1 Integrin Targeting Potentiates Antiangiogenic Therapy and Inhibits the Growth of Bevacizumab-Resistant Glioblastoma
Authors: Carbonell W. Shawn , DeLay Michael , Jahangiri Arman , Park Catherine C. , Aghi Manish K.
Published: April 2023

PDF file - 915K, Supplementary Figure 1. Bevacizumab Treatment Promotes Invasiveness Of GBM. Supplementary Figure 2. Increased Expression Of Beta1 In The U87-BEV Cell Line. Supplementary Figure 3. Beta1 Integrin Expression In GBM Associated With Cellular Insults And Mesenchymal Phenotype. Supplementary Figure 4. Establishment And Characterization Of Stable Beta1 Knockdown Clones In The BRG3 Line. Supplementary Figure 5. Beta1 integrin knockdown in resistant GBM cells inhibits mesenchymal phenotype. Supplementary Figure 6. Inhibitory Anti-Beta1 Mab OS2966 Attenuates Adhesion And Proliferation Of BRG Cells. Supplementary Figure 7. A Role For Beta1 In Spheroidal Growth Of U87MG Glioma Cell Line. Supplementary Figure 8. Beta1 Inhibition In Xenograft Models.
Supplementary Figure 5 from p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model
Authors: Chow Hoi Yee , Jubb Adrian M. , Koch Jennifer N. , Jaffer Zahara M. , Stepanova Dina , Campbell David A. , Duron Sergio G. , O'Farrell Marie , Cai Kathy Q. , Klein-Szanto Andres J.P. , Gutkind J. Silvio , Hoeflich Klaus P. , Chernoff Jonathan
Published: April 2023

PDF file - 60K, Schematic presentation of Ras-mediated Pak1 signaling
Supplementary Figure 2 from Rab25 Is a Tumor Suppressor Gene with Antiangiogenic and Anti-Invasive Activities in Esophageal Squamous Cell Carcinoma
Authors: Tong Man , Chan Kwok Wah , Bao Jessie Y.J. , Wong Kai Yau , Chen Jin-Na , Kwan Pak Shing , Tang Kwan Ho , Fu Li , Qin Yan-Ru , Lok Si , Guan Xin-Yuan , Ma Stephanie
Published: April 2023

PDF file, 720K, Detection of DNA copy number change of Rab25 by dual-color fluorescent in situ hybridization (FISH) in ESCC cell lines KYSE520, EC109 and formalin-fixed paraffin-embedded ESCC clinical tissue specimens (#1 and #2) with no or low Rab25 expression. BAC probe to Rab25 and the control reference probe to the centromere of chromosome 1 are represented by red and green signals, respectively. Magnification at 1000x.
Supplementary Figure 3 from p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model
Authors: Chow Hoi Yee , Jubb Adrian M. , Koch Jennifer N. , Jaffer Zahara M. , Stepanova Dina , Campbell David A. , Duron Sergio G. , O'Farrell Marie , Cai Kathy Q. , Klein-Szanto Andres J.P. , Gutkind J. Silvio , Hoeflich Klaus P. , Chernoff Jonathan
Published: April 2023

PDF file - 126K, Activity of FRAX-597 against group A and group B Paks
Supplementary Figure 2 from p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model
Authors: Chow Hoi Yee , Jubb Adrian M. , Koch Jennifer N. , Jaffer Zahara M. , Stepanova Dina , Campbell David A. , Duron Sergio G. , O'Farrell Marie , Cai Kathy Q. , Klein-Szanto Andres J.P. , Gutkind J. Silvio , Hoeflich Klaus P. , Chernoff Jonathan
Published: April 2023

PDF file - 232K, Immunohistochemical analysis of P-Erk, P-Akt, P-S6, and beta-catenin in tumors arising in K5-tTR::tet-Kras mice
Supplementary Table 5 from Activation of Robo1 Signaling of Breast Cancer Cells by Slit2 from Stromal Fibroblast Restrains Tumorigenesis via Blocking PI3K/Akt/β-Catenin Pathway
Authors: Chang Po-Hao , Hwang-Verslues Wendy W. , Chang Yi-Cheng , Chen Chun-Chin , Hsiao Michael , Jeng Yung-Ming , Chang King-Jen , Lee Eva Y.-H.P. , Shew Jin-Yuh , Lee Wen-Hwa
Published: April 2023

PDF file, 25K, Characteristics of 51 breast cancer patients in the third cohort used to determine the clinical correlation of Slit2 mRNA expression (Fig. 6D).
Supplementary Table 2 from Activation of Robo1 Signaling of Breast Cancer Cells by Slit2 from Stromal Fibroblast Restrains Tumorigenesis via Blocking PI3K/Akt/β-Catenin Pathway
Authors: Chang Po-Hao , Hwang-Verslues Wendy W. , Chang Yi-Cheng , Chen Chun-Chin , Hsiao Michael , Jeng Yung-Ming , Chang King-Jen , Lee Eva Y.-H.P. , Shew Jin-Yuh , Lee Wen-Hwa
Published: April 2023

PDF file, 26K, Characteristics of 122 breast cancer patients in the first cohort used to determine the clinical correlation of Robo1 mRNA expression (Fig. 6A).
Supplementary Figure Legends 1-5 from Chromatin Remodeling Underlies the Senescence-Associated Secretory Phenotype of Tumor Stromal Fibroblasts That Supports Cancer Progression
Authors: Pazolli Ermira , Alspach Elise , Milczarek Agnieszka , Prior Julie , Piwnica-Worms David , Stewart Sheila A.
Published: April 2023

PDF file - 67K
Supplementary Figure 1 from Real-time Monitoring of In Vivo Acute Necrotic Cancer Cell Death Induced by Near Infrared Photoimmunotherapy Using Fluorescence Lifetime Imaging
Authors: Nakajima Takahito , Sano Kohei , Mitsunaga Makoto , Choyke Peter L. , Kobayashi Hisataka
Published: April 2023

PDF file - 26K, Lapatinib induces a homologous recombination repair defect in HER2+ breast cancer cell
Supplementary Figure 4 from The Mixed Lineage Leukemia (MLL) Fusion–Associated Gene AF4 Promotes CD133 Transcription
Authors: Mak Anthony B. , Nixon Allison M.L. , Moffat Jason
Published: April 2023

PDF file - 104K
Supplementary Figure 3 from The Mixed Lineage Leukemia (MLL) Fusion–Associated Gene AF4 Promotes CD133 Transcription
Authors: Mak Anthony B. , Nixon Allison M.L. , Moffat Jason
Published: April 2023

PDF file - 453K
Supplementary Table 4 from DNA Methylation Biomarkers Offer Improved Diagnostic Efficiency in Lung Cancer
Authors: Nikolaidis Georgios , Raji Olaide Y. , Markopoulou Soultana , Gosney John R. , Bryan Julie , Warburton Chris , Walshaw Martin , Sheard John , Field John K. , Liloglou Triantafillos
Published: April 2023

PDF file - 53K, Nucleotide sequences of methylation specific primers and probes for the qMSP assays utilised in the BW screening. The ACTB assay is methylation independent
Supplementary Table 3 from DNA Methylation Biomarkers Offer Improved Diagnostic Efficiency in Lung Cancer
Authors: Nikolaidis Georgios , Raji Olaide Y. , Markopoulou Soultana , Gosney John R. , Bryan Julie , Warburton Chris , Walshaw Martin , Sheard John , Field John K. , Liloglou Triantafillos
Published: April 2023

PDF file - 57K, Nucleotide sequences of PCR and sequencing primers for Pyrosequencing Methylation Analysis of the promoter targets which qualified for the subsequent BW screening
Supplementary Figures 1-7, Table 1, Methods from Oncostatin M Modulates the Mesenchymal–Epithelial Transition of Lung Adenocarcinoma Cells by a Mesenchymal Stem Cell-Mediated Paracrine Effect
Authors: Wang Mong-Lien , Pan Chih-Ming , Chiou Shih-Hwa , Chen Wen-Hsin , Chang Hsiang-Yi , Lee Oscar Kuang-Sheng , Hsu Han-Sui , Wu Cheng-Wen
Published: April 2023

PDF file - 451K, Suppl. Fig. 1 Characterization of BM-MSC surface markers. Suppl. Fig. 2 MSC derived from different donors inhibited LAC cell migration. Suppl. Fig. 3 MSC expresses and secretes OSM. Suppl. Fig. 4 OSM inhibited the proliferation of CL1-5 and A549 LAC cells. Suppl. Fig. 5 OSM inhibited the migratory capability of lung squamous cell carcinoma. Suppl. Fig. 6 STAT3 did not mediate the OSM-dependent inhibition of EMT markers. Suppl. Fig. 7 OSM mediated the MSC-CM-dependent suppression of tumor proliferation and EMT in vivo. Suppl. Table 1 List of antibodies used in the report
Supplementary Methods, Figures 1-5 from Effective Photothermal Chemotherapy Using Doxorubicin-Loaded Gold Nanospheres That Target EphB4 Receptors in Tumors
Authors: You Jian , Zhang Rui , Xiong Chiyi , Zhong Meng , Melancon Maritess , Gupta Sanjay , Nick Alpa M. , Sood Anil K. , Li Chun
Published: April 2023

PDF file - 835K, 1. Reagents 2. Synthesis of cyclic peptide c(TNYL-RAW) (Lys-Thr-Asn-Tyr-Leu-Phe-Ser-Pro-Asn-Gly-Pro-ILe-Ala-Arg-Ala-Trp-Asp) 3. Radiolabeling of HAuNS with 111In 4. SPR assay of receptor binding affinity 5. Cell culture 6. Analysis of EphB4 expression fig. S1. Physical properties of HAuNS. Fig. S2. Binding affinity and plasma stability of c(TNYL-RAW). fig. S2. Western blot analysis and immunostaining of EphB4 expression. fig. S3. Cell viability as a function of equivalent DOX concentration. fig. S4. Body weight change after the initiation of various treatments.
Supplementary Figure 3 from A Universal Strategy for Adoptive Immunotherapy of Cancer through Use of a Novel T-cell Antigen Receptor
Authors: Urbanska Katarzyna , Lanitis Evripidis , Poussin Mathilde , Lynn Rachel C. , Gavin Brian P. , Kelderman Sander , Yu Jason , Scholler Nathalie , Powell Daniel J.
Published: April 2023

PDF file - 113K, Flow Cytometry analysis of an antigen surface expression on mouse AE17 cell lines transduced to express human FR�� or mesothelin and human ovarian cancer cell line, A1847. FR��-specific mAb Mov18, EpCAM-specific and mesothelin-specific K1 antibody and P4 Biobody were used to measure antigen expression on tumor cell lines (open empty histogram), compared to a matched isotype Ab control (filled gray histogram). Numbers within plots refer to specific mean fluorescent intensity (MFI).
Supplementary Figure 5 from PNUTS Functions as a Proto-Oncogene by Sequestering PTEN
Authors: Kavela Sridhar , Shinde Swapnil R. , Ratheesh Raman , Viswakalyan Kotapalli , Bashyam Murali D. , Gowrishankar Swarnalata , Vamsy Mohana , Pattnaik Sujit , Rao Subramanyeshwar , Sastry Regulagadda A. , Srinivasulu Mukta , Chen Junjie , Maddika Subbareddy
Published: April 2023

PDF file - 128K, PNUTS promotes cell survival signaling in PTEN dependent manner
Supplementary Figure 4 from NLRR1 Enhances EGF-Mediated MYCN Induction in Neuroblastoma and Accelerates Tumor Growth In Vivo
Authors: Hossain Shamim , Takatori Atsushi , Nakamura Yohko , Suenaga Yusuke , Kamijo Takehiko , Nakagawara Akira
Published: April 2023

PDF file, 83K, NLRR1-stably expression in cells leads to oncogenic characteristics. NLRR1 expression enhances colony formation ability of cells. NMYC expression is induced in the NLRR1 stably expressing clones and found to grow faster than the mock clones.
Supplementary Figure 5 from Canonical Wnt Signaling Is Required for Pancreatic Carcinogenesis
Authors: Zhang Yaqing , Morris John P. , Yan Wei , Schofield Heather K. , Gurney Austin , Simeone Diane M. , Millar Sarah E. , Hoey Timothy , Hebrok Matthias , Pasca di Magliano Marina
Published: April 2023

PDF file - 4422K, Supplemental Figure 5. Survival curve of KC and KDC mice. PDA in KC and KDC mice.
Supplementary Figures 1-5, Table 1 from A RASSF1A Polymorphism Restricts p53/p73 Activation and Associates with Poor Survival and Accelerated Age of Onset of Soft Tissue Sarcoma
Authors: Yee Karen S. , Grochola Lukasz , Hamilton Garth , Grawenda Anna , Bond Elisabeth E. , Taubert Helge , Wurl Peter , Bond Gareth L. , O'Neill Eric
Published: April 2023

PDF file - 207K
Supplementary Figure 2 from Autophagy Induced by Conventional Chemotherapy Mediates Tumor Cell Sensitivity to Immunotherapy
Authors: Ramakrishnan Rupal , Huang Chun , Cho Hyun-Il , Lloyd Mark , Johnson Joseph , Ren Xiubao , Altiok Soner , Sullivan Daniel , Weber Jeffrey , Celis Esteban , Gabrilovich Dmitry I.
Published: April 2023

PDF file - 231K, Effect of treatment on tumor progression using bioluminescence imaging
Supplementary Figure 4 from Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay
Authors: Fiaschi Tania , Marini Alberto , Giannoni Elisa , Taddei Maria Letizia , Gandellini Paolo , De Donatis Alina , Lanciotti Michele , Serni Sergio , Cirri Paolo , Chiarugi Paola
Published: April 2023

PDF file - 818K, MCT1 transporter is important for PCa cell growth; A) MCT1 transporter is up-regulated in PCa cells. PCa cells were cultivated alone or in co-colture with CAFs (3:1 CAFs:PCa cells proportion). Cells were then treated with CM-HPFs, CM-CAFs or serum-free medium for 24 hours and then MCT1 and MCT4 expression was valutated by immunoblot analysis. B)MCT1 silencing decreases the growth of PCa clones. MCT1 silencing was obtained by RNA interference in PCa cells. 48 hours after silencing, PCa cells were used to seed a co-colture with CAFs (5:1, CAFs:PCa cells proportion). PCa clones are counted after five, six and seven days and the mean are shown in the bar graph.
Supplementary Figure Legends from BMP-6 in Renal Cell Carcinoma Promotes Tumor Proliferation through IL-10–Dependent M2 Polarization of Tumor-Associated Macrophages
Authors: Lee Jae-Ho , Lee Geun Taek , Woo Seung Hyo , Ha Yun-Sok , Kwon Seok Joo , Kim Wun-Jae , Kim Isaac Yi
Published: April 2023

Supplementary Figure Legends - PDF file 73K, Supplementary figure legends
Supplementary Figure 9 from HMGA2 Is a Driver of Tumor Metastasis
Authors: Morishita Asahiro , Zaidi M. Raza , Mitoro Akira , Sankarasharma Devipriya , Szabolcs Matthias , Okada Yasunori , D'Armiento Jeanine , Chada Kiran
Published: April 2023

Supplementary Figure 9 - PDF file 83K, TGFBeta 1 mRNA expression in MCF7, MCF-HMGA2, and MDA-MB231 human breast cancer cells as detected by qRT-PCR
Supplementary Figure 3 from Dual Blockade of PD-1 and CTLA-4 Combined with Tumor Vaccine Effectively Restores T-Cell Rejection Function in Tumors
Authors: Duraiswamy Jaikumar , Kaluza Karen M. , Freeman Gordon J. , Coukos George
Published: April 2023

Supplementary Figure 3 - PDF file 26K, in vivo depletion of total CD8+ and CD4+ T cells totally abolished CT26 tumor regression. Survival of mice inoculated with 0.5 x 106 CT26 tumor cells and injected i.p. with �CD4 (GK1.5, 500 �g) or �CD8 antibodies (19/178, 500 �g) day -1 and 0 (resulting in >90% of CD4+ or CD8+ T-cell depletion, respectively). Tumor size of >200mm3 was defined as lack of survival. Each curve is representative of 3 independent experiments of 12 mice per group
Supplementary Figure 5 from Opposing Roles for IL-23 and IL-12 in Maintaining Occult Cancer in an Equilibrium State
Authors: Teng Michele W. L. , Vesely Matthew D. , Duret Helene , McLaughlin Nicole , Towne Jennifer E. , Schreiber Robert D. , Smyth Mark J.
Published: April 2023

PDF file - 249K, Role of CD11c+ DC and neutrophils in equilibrium
Supplementary Figures 1-6 from BMP4 Administration Induces Differentiation of CD133+ Hepatic Cancer Stem Cells, Blocking Their Contributions to Hepatocellular Carcinoma
Authors: Zhang Lixing , Sun Hefen , Zhao Fangyu , Lu Ping , Ge Chao , Li Hong , Hou Helei , Yan Mingxia , Chen Taoyang , Jiang Guoping , Xie Haiyang , Cui Ying , Huang Xiaowu , Fan Jia , Yao Ming , Li Jinjun
Published: April 2023

PDF file - 639K, Supplementary Figure 1. CD133 is CSCs surface marker in PLC/PRF/5 cell line. Supplementary Figure 2. BMP4 showed pro-differentiation effect on HCC cell lines. Supplementary Figure 3. Tumorigenicity of CD133+/- HCC cells co-injected with BMP4 or vehicle embedding beads. Supplementary Figure 4. Canonical BMP4 signaling pathway switches on after exogenous BMP4 treatment. Supplementary Figure 5. BMP4 and SMAD6 expression in HCC cell lines. Supplementary Figure 6. Differentiated CSCs displayed enhanced Erk1/2 phosphorylation.
Supplementary Tables 1 through 8 from Metabolic Associations of Reduced Proliferation and Oxidative Stress in Advanced Breast Cancer
Authors: Jerby Livnat , Wolf Lior , Denkert Carsten , Stein Gideon Y. , Hilvo Mika , Oresic Matej , Geiger Tamar , Ruppin Eytan
Published: April 2023

XLS file, 80K, The file includes the following tables: 1. A description of the metabolic processes utilized as input for MPA. 2. Comparison between the MPA profiles of three human tissues: liver, adipose and muscle. 3. The relation between measured lipids in BC, to the gene expression and MPA scores of de-novo lipogenesis reactions. 4. Analysis of PC(14:0,16:0): Correlation between its level and reaction expression. 5. AUCs obtained in the classification of BC samples. 6. Comparison between the MPA profiles of early and late stage tumors. 7. Comparison between the MPA profiles of ER+ and ER- tumors. 8. The top ten biomarkers predicted for metastatic BC, or only for metastatic ER+ BC.
Supplementary Figure 1 from Gliomagenesis Arising from Pten- and Ink4a/Arf-Deficient Neural Progenitor Cells Is Mediated by the p53-Fbxw7/Cdc4 Pathway, Which Controls c-Myc
Authors: Kim Hong Sug , Woolard Kevin , Lai Chen , Bauer Peter O. , Maric Dragan , Song Hua , Li Aiguo , Kotliarova Svetlana , Zhang Wei , Fine Howard A.
Published: April 2023

PDF file, 167K, Establishment of mNSCs.
Supplementary Figure 1 from miRNA-34 Prevents Cancer Initiation and Progression in a Therapeutically Resistant K-ras and p53-Induced Mouse Model of Lung Adenocarcinoma
Authors: Kasinski Andrea L. , Slack Frank J.
Published: April 2023

PDF file - 93K, In eight out of ten ad-cre infected animals the lungs were proportionally larger than uninfected controls while the size of the liver and kidney remained unaltered.
Supplementary Figure Legend from Macrophage Delivery of an Oncolytic Virus Abolishes Tumor Regrowth and Metastasis after Chemotherapy or Irradiation
Authors: Muthana Munitta , Rodrigues Samuel , Chen Yung-Yi , Welford Abigail , Hughes Russell , Tazzyman Simon , Essand Magnus , Morrow Fiona , Lewis Claire E.
Published: April 2023

PDF file - 88K
Supplementary Figure 1 from Macrophage Delivery of an Oncolytic Virus Abolishes Tumor Regrowth and Metastasis after Chemotherapy or Irradiation
Authors: Muthana Munitta , Rodrigues Samuel , Chen Yung-Yi , Welford Abigail , Hughes Russell , Tazzyman Simon , Essand Magnus , Morrow Fiona , Lewis Claire E.
Published: April 2023

PDF file - 454K, Macrophage delivery of an oncolytic virus (Ad1/PPT-E1A) abolishes the regrowth of human prostate (LUC-LNCaP) tumors after treatment with the cytotoxic agent, docetaxel (DOX)
Supplementary Figures 1 - 8 from TRAF4 Is a Critical Molecule for Akt Activation in Lung Cancer
Authors: Li Wei , Peng Cong , Lee Mee-Hyun , Lim DoYoung , Zhu Feng , Fu Yang , Yang Ge , Sheng Yuqiao , Xiao Lanbo , Dong Xin , Ma WeiYa , Bode Ann M. , Cao Ya , Dong Zigang
Published: April 2023

PDF file - 1503K, Supplementary Figure 1. Knockdown of TRAF4 reduces tumorigenic properties in a panel of human lung cancer cell lines. Supplementary Figure 2. Knockdown of TRAF4 inhibits EGF-induced translocation of Akt to the membrane. Supplementary Figure 3. TRAF6 is unnecessary for EGF-induced Akt activation in human lung cancer cells. Supplementary Figure 4. TRAF4, but not Skp2, is overexpressed and required for Akt activation in human lung cancer cell lines. Supplementary Figure 5. The Ring domain and TRAFc domain are required for TRAF4-mediated HaCaT cell malignant transformation. Supplementary Figure 6. Knockdown of Akt1 inhibits EGF-induced HaCaT cell transformation. Supplementary Figure 7. Knockdown of Akt1 reduces tumorigenic properties of human lung cancer cells. Supplementary Figure 8. Cell counting. Cells that used for glucose uptake and lactate production measurement were counted.
Supplementary Figure 5 from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
Authors: Kikuchi Koji , Narita Takeo , Pham Van T. , Iijima Junko , Hirota Kouji , Keka Islam Shamima , Okawa Katsuya , Hori Tetsuya , Fukagawa Tatsuo , Essers Jeroen , Kanaar Roland , Whitby Matthew C. , Sugasawa Kaoru , Taniguchi Yoshihito , Kitagawa Katsumi , Takeda Shunichi
Published: April 2023

PDF file - 139K, Schematic representation of EME1 disruption in DT40 cells.
Supplementary Methods and References from Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer
Authors: Abazeed Mohamed E. , Adams Drew J. , Hurov Kristen E. , Tamayo Pablo , Creighton Chad J. , Sonkin Dmitriy , Giacomelli Andrew O. , Du Charles , Fries Daniel F. , Wong Kwok-Kin , Mesirov Jill P. , Loeffler Jay S. , Schreiber Stuart L. , Hammerman Peter S. , Meyerson Matthew
Published: April 2023

PDF file, 156K.
Supplementary Figure 4 from Structure-Specific Endonucleases Xpf and Mus81 Play Overlapping but Essential Roles in DNA Repair by Homologous Recombination
Authors: Kikuchi Koji , Narita Takeo , Pham Van T. , Iijima Junko , Hirota Kouji , Keka Islam Shamima , Okawa Katsuya , Hori Tetsuya , Fukagawa Tatsuo , Essers Jeroen , Kanaar Roland , Whitby Matthew C. , Sugasawa Kaoru , Taniguchi Yoshihito , Kitagawa Katsumi , Takeda Shunichi
Published: April 2023

PDF file - 130K, Co-immunoprecipitation of Xpf with Eme1 or Slx4.
Supplementary Procedures and Figure Legends from Notch1 Is Required for Kras-Induced Lung Adenocarcinoma and Controls Tumor Cell Survival via p53
Authors: Licciulli Silvia , Avila Jacqueline L. , Hanlon Linda , Troutman Scott , Cesaroni Matteo , Kota Smitha , Keith Brian , Simon M. Celeste , Puré Ellen , Radtke Fred , Capobianco Anthony J. , Kissil Joseph L.
Published: April 2023

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Supplementary Figures 1 - 9 from OX40 Is a Potent Immune-Stimulating Target in Late-Stage Cancer Patients
Authors: Curti Brendan D. , Kovacsovics-Bankowski Magdalena , Morris Nicholas , Walker Edwin , Chisholm Lana , Floyd Kevin , Walker Joshua , Gonzalez Iliana , Meeuwsen Tanisha , Fox Bernard A. , Moudgil Tarsem , Miller William , Haley Daniel , Coffey Todd , Fisher Brenda , Delanty-Miller Laurie , Rymarchyk Nicole , Kelly Tracy , Crocenzi Todd , Bernstein Eric , Sanborn Rachel , Urba Walter J. , Weinberg Andrew D.
Published: April 2023

PDF file - 198K, Figure 1. Characterization of the anti-OX40 mAb (9B12). Figure 2. Total peripheral lymphocyte counts. Figure 3. Pharmacokinetics of CD134 (anti-OX40) mAb in patients. Figure 4. Direct ex vivo detection of the murine anti-OX40 mAb bound to T cells in treated patients. Figure 5. Regression of a pulmonary metastasis in a patient with renal carcinoma enrolled in cohort 1. Figure 6. Changes in Ki-67 expression within CD4+ and CD8+ T cell subsets examined over time after anti-OX40 from patients in cohorts 1 and 2. Figure 7. Increased proliferation of CD4+ Foxp3- T cells and CD8+ T cells correlates with a decrease or stabilization of tumor burden. Figure 8. Ki-67 expression by monkey CD4+ and CD8+ memory T cells after the administration of anti-OX40 , mouse Immunoglobulin or monkey OX40L:Ig. Figure 9. Determination of the Endpoint Titer for anti-KLH Ab.
Supplementary Materials and Methods from Erlotinib Resistance in Lung Cancer Cells Mediated by Integrin β1/Src/Akt-Driven Bypass Signaling
Authors: Kanda Rina , Kawahara Akihiko , Watari Kosuke , Murakami Yuichi , Sonoda Kahori , Maeda Masashi , Fujita Hideaki , Kage Masayoshi , Uramoto Hidetaka , Costa Carlota , Kuwano Michihiko , Ono Mayumi
Published: April 2023

PDF - 82K, Supplementary materials and methods.
Supplementary Figure 2 from Interleukin-6 Is Required for Pancreatic Cancer Progression by Promoting MAPK Signaling Activation and Oxidative Stress Resistance
Authors: Zhang Yaqing , Yan Wei , Collins Meredith A. , Bednar Filip , Rakshit Sabita , Zetter Bruce R. , Stanger Ben Z. , Chung Ivy , Rhim Andrew D. , di Magliano Marina Pasca
Published: April 2023

PDF file - 184K, Characterization of pancreatic immune infiltrate in iKras*;IL6-/- mice.
Supplementary Methods from Indirubin Derivative 6BIO Suppresses Metastasis
Authors: Braig Simone , Kressirer Christine A. , Liebl Johanna , Bischoff Fabian , Zahler Stefan , Meijer Laurent , Vollmar Angelika M.
Published: April 2023

PDF file, 70K.