bluuebunny/crossref_metadata_2025 huggingface dataset:
miR-146a geno ir jo reguliuojamo IRAK-1 geno variantų nustatymas bei sąsajų su žvynelinės požymiais analizė
Authors: Bružaitė Akvilė , Liutkevičienė Rasa
Published: November 2022

Žvynelinė – autoimuninė lėtinė uždegiminė odos liga, sąlygota genetinių, epigenetinių bei aplinkos veiksnių. Šios ligos atsiradimas ir vystymasis yra susijęs su imuninės sistemos ląstelių, uždegiminių mediatorių bei keratinocitų tarpusavio sąveika. Atlikti tyrimai rodo, kad genetinės bei epigenetinės anomalijos, kurias reguliuoja mikroribonukleininės rūgštys (miRNR), yra stipriai susijusios su žvynelinės pasireiškimu. miR-146a – tai neigiamai veikiantis reguliatorius uždegiminiuose, autoimuniniuose, patologiniuose procesuose, virusinės infekcijos metu bei įgimtame imuniniame atsake. Ieškant sąsajos tarp miR-146a ir žvynelinės, pastebėta, kad padidėjęs minėtos miRNR kiekis gali sąlygoti ankstyvą ligos pasireiškimą, ūminius epidermio uždegimus bei citokinų reguliacijos sutrikimus. miR-146a reguliuoja genus, kurie yra atsakingi už darnią organizmo veiklą, tačiau svarbiausi genai-taikiniai, susiję su žvyneline, yra IRAK-1 ir TRAF-6. IRAK-1 genas turi kelis VNV, kurie yra susiję su autoimuninių uždegiminių ligų pasireiškimu. Labiausiai žinomi VNV, dėl kurių galimai gali pasireikšti šios ligos, yra rs1059703 ir rs3027898. IRAK-1 rs3027898 A > C variantas yra siejamas su reumatoidinio artrito pasireiškimu ir manoma, kad rs3027898C alelis gali turėti įtakos odos uždegiminių ligų pasireiškimui. IRAK-1 rs1059703 T > C variantas siejamas su lėtiniu inkstų uždegimu, sepsiu.
Aktininė keratozė – ikinavikinė odos liga. Literatūros apžvalga
Authors: Sniečkutė Ieva , Sakalauskienė Ilona
Published: November 2022

Aktininė keratozė (toliau – AK) – ikivėžinis odos susirgimas, pasireiškiantis kūno spalvos (rusvomis) šiurkščiomis arba pleiskanojančiomis dėmelėmis arba plokštelėmis. Dažniausiai jos susiformuoja saulės nepridengtose kūno vietose (veido, dažniausiai – nosies, viršugalvio, ausų odoje). Svarbiausias rizikos veiksnys – ilgalaikis ultravioletinių (toliau – UV) saulės spindulių poveikis. UVA spindulių sukeltas fotooksidacinis stresas netiesiogiai skatina keratinocitų DNR mutacijų atsiradimą, o UVB spinduliai tiesiogiai pažeidžia DNR ir RNR. Tinkamo gydymo metodo parinkimas – individualus procesas, kuris priklauso nuo AK lokalizacijos, pažaidų daugybiškumo, paciento amžiaus ir kt. Gydymas skirstomas į vietinį medikamentinį ir destrukcinį. Esant pavieniams AK atvejams, rekomenduojama rinktis destrukcinius metodus: krioterapiją ir kiuretažą su (be) elektrokoaguliacija. Kiuretažui pirmenybę reikėtų teikti, esant storoms, hiperkeratozinėms AK. Lazeris ir ekscizija – antrojo pasirinkimo metodai,  gydant rezistentiškus arba recidyvuojančius AK atvejus. Jei odos pažeidimas kelia įtarimą dėl galimo piktybėjimo, būtina atlikti pažeistos vietos biopsiją arba eksciziją. Kai nustatomos dauginės AK, jas gydyti derėtų vietinio poveikio medikamentais (0,5 proc., 5 proc. 5-fluorouracilu (toliau – 5-FU), 3,75 proc., 5 proc. imikvimodu ir 0,015 proc., 0,05 proc. ingenolio mebutatu) ir fotodinamine terapija (toliau – FDT). Iki 20 proc. atvejų AK progresuoja į plokščiųjų ląstelių karcinomą (toliau – PLK), todėl jas būtina gydyti.
Building Positive Mental Resilience for Santri
Authors:   Master of Islamic Science /University Muhammadiyah Yogyakarta), Indonesia, rahmatullah azam syukur , Eko Atmojo Muhammad ,   Departemen of government/University Muhammadiyah Yogyakarta), Indonesia
Published: November 2022

This study aims to discover what and how to develop positive mental resilience at Madrasah Diniyyah Puteri Padang Panjang, West Sumatra. Even though all the santri are female, they are still equipped with endurance, mentality, self-strength, and struggle tips. Madrasah Diniyyah Puteri Padang Panjang continues to provide mental-based programs. Hence, the santri can later stand on their feet and become messengers of goodness and virtue for the wider community. This research is naturalistic qualitative research and uses an ethnomethodological approach. The research subjects were selected and randomized using a purposive sampling technique with a snowball model. The results showed that female students’ resilience at Madrasah Diniyyah Padang Panjang, West Sumatra, has essentially been based on a solid foundation by Rahmah El Yunusiyyah. A reliable mental education forerunner is then sown to the next generation yearly. The mental character remains strong and thrives. Several factors leading to this resilience were presented, grounded, and propagated in Madrasah Diniyyah Padang Panjang, West Sumatra; first, preserving the ancestral heritage; second, the factors of mental regeneration of women; third, the characteristics for degrading women by irresponsible persons. The programs for female students were: A Good Leader Program, Super Santri Camp Program, Dream Realization Program, Santri Pledge Program, and Character Survey Program, Room Shifting Program.
Strategy For The Development Of A School Plan At The Kesuma Elkaemde Namorambe Education Foundation
Authors:   State Islamic University of North Sumatra, Mesiono Mesiono , Nasution Sri Rahayu , Azmar Azmar ,   State Islamic University of North Sumatra, Nazri Elfin ,   State Islamic University of North Sumatra
Published: November 2022

There are often problems in the preparation of school development plans, starting with a lack of assistance, supervision, competence and unsystematic plans made. Thus, the purpose of this study was to describe the school development plan at the Kesuma Elkaemde Education Foundation. This research is a qualitative research. The subjects of this research are principals, teachers, and all other devices that take part in the preparation of school plans. The data collection technique of this research is by interview, observation and documentation. After that, the data were analyzed by examining the data that had been collected, namely data reduction, verification, and data presentation. The results show that the school development plan at the Kesuma Elkaemde Education Foundation implements a school development plan by carrying out a Short-Term Annual Program Strategy which includes the First Year Program (2018–2019), Second Year Program (2019–2020), Third Year Program (2020–2021 ), Fourth Year Program (2021–2022). In addition, there is also a 12-year Long-Term Program Strategy in the form of vision, mission and goals. And every development plan that is prepared is oriented to character and cultural education oriented to systems of thinking, values, morals and beliefs.
Management Financing In Improving The Quality Of Education
Authors:   Universitas Negeri Medan, Jaya Togi Van , Sitanggang Nathanael ,   Universitas Negeri Medan, Lubis M. Joharis ,   Universitas Negeri Medan
Published: November 2022

This study aims to determine the management of education financing in relation to efforts to improve the quality of education. This study focuses on the study of how the influence of financial management of education on quality of educationof the PKBM PELITA, Deli Serdang Regency. This research uses qualitative methods based on descriptive studies. Data collection techniques using observation, interviews, and documentation studies. Data analysis was performed using the Miles and Huberman model stages, namely data reduction, data presentation, and conclusion drawing. The data validity test used triangulation and member crosscheck. The results showed that the management of educational finance had been done well 1) the process of budgeting according to the procedure; 2) sources of finance obtained from several sources of funds; 3) the constraining factor in the management of educational finance belongs to the flow of disbursement of funds long enough; 4) supervision and accountability in the educational finance is going well; and 5) Foundations, principals, vice principals, treasurers, school committees, teachers and UPTD Education involved in the education finance management process
Guía de procedimientos del Comité Institucional de Ética para la Investigación
Authors:   Universidad Privada Norbert Wiener, Bellido Fuentes Yenny Marisol
Published: November 2022

La presente Guía de procedimientos del Comité Institucional de Ética para la Investigación detalla, a manera de resumen, los procedimientos para la presentación de expedientes, antes de la ejecución del estudio, y durante y al concluir la respectiva investigación aprobada por el CIEI-UPNW. La guía está dirigida a estudiantes, docentes, investigadores, administrativos y colaboradores de la Universidad Privada Norbert Wiener (UPNW) vinculados a la ejecución de un proyecto de investigación. Su propuesta está en concordancia con el Manual de procedimientos del CIEI-UPNW_Versión_2 (2022), aprobado el 22 de septiembre de 2022 por la Resolución de Gerencia General n.° 089-2022-GG-UPNW.
GESTIÓN UNIVERSITARIA PERSPECTIVA TRANSCOMPLEJA DE LA INTELIGENCIA ORGANIZACIONAL EN LA ERA POSTHUMANA PARA LA UNIVERSIDAD POLITÉCNICA TERRITORIAL JOSÉ ANTONIO ANZOÁTEGUI
Authors:   Juan José Hernández Marcan, Astudillo Escalona Carlena Josefina
Published: November 2022

Las rutas direccionadoras de la investigación se orientaron a conocer, develar y comprender los significados intersubjetivos de la dinámica gerencial vivenciada desde la transcomplejidad, a los fines de configurar un corpus teórico de gestión universitaria en la UPTJAA, que orientó un proceso de modelación. El estudio se enmarcó en el enfoque transcomplejo, desde la visión transparadigmatica, donde hubo la apropiación de los principios de la intersubjetividad, la dialogicidad, la comprensión, la cotidianidad y el carácter ideográfico del saber. El proceder investigativo se sustentó en el transmétodo, guiado por un diseño abierto, flexible y recursivo propio de la perspectiva transcompleja. La recolección de la información se realizó mediante la entrevista en profundidad, aplicada a doce (12 )Versionantes miembros de diferentes sectores de la comunidad académico administrativa de la universidad; y consecuentemente se procedió al proceso de sistematización hermenéutica en la que se develó algunas categorías significativas denominadas transcategoría la cuales se definieron como raciocinio integral organizacional, raciocinio académico organizacional y raciocinio territorial organizacional desde donde emergió mediante una Hermeneusis una configuración teórica con base en cuatro inteligencias denominadas avenencias (zócalo, erudita, geoespacial y holista), de la cuales emergieron cinco regeneraciones inteligentes a saber: basa, docta, geomorfológica, harmónica y avatar; prorrumpiendo un modelo transinteligente de gestión universitaria para la UPTJAA.
Subjective Well Being Wanita Terlantar Pada Era New Normal Pandemi Covid-19 di Panti Sosial Perlindungan Jakarta
Authors: Yani Devi Antap , Sovitriana Rilla
Published: November 2022

Penelitian ini bertujuan untuk mengetahui ada hubungan dukungan sosial temansebaya dan optimisme dengan subjective well being pada wanita terlantar yang beradadi Panti Sosial Perlindungan Bhakti Kasih. Jumlah sampel yang digunakan padapenelitian ini adalah wanita terlantar di Panti Sosial Perlindungan Bhakti Kasih yangberjumlah 92 orang. Pengujian hipotesis menggunakan teknik analisa bivariatecorrelation dan multivariate correlation dengan menggunakan SPSS forwindows. Teknik pengambilan sampel mengggunakan metode sampel jenuhyaitu teknik penentuan sampel bila semua anggota populasi digunakan menjadisampel. Pengambilan data sampel dilakukan dengan menggunakan penyebarankuisioner mengenai dukungan sosial teman sebaya dan optimisme dengan subjectivewell being. Berdasarkan analisis data yang dilakukan dengan bivariate correlation,diketahui hasil koefisien korelasi antara dukungan sosial teman sebaya dengansubjective well being sebesar r = 0,469 dengan taraf signifikansi 0,000 (p<0,05)artinya terdapat hubungan positif antara dukungan sosial teman sebaya dengansubjective well being dan hasil korelasi antara hubungan optimisme dengansubjective well being sebesar r = 0,394 dengan taraf signifikansi 0,000 (p<0,05)artinya terdapat hubungan yang positif antara optimisme dengan subjective wellbeing, sedangkan hasil analisis yang dilakukan dengan multivariate correationhasil korelasi antara hubungan dukungan sosial dan optimisme dengan subjective wellbeing sebesar R = 0,507 dengan taraf signifikasi sebesar 0,000 (p<0,05) artinyaterdapat hubungan yang positif antara dukungan sosial teman sebaya dan optimismedengan subjective well being. Dimana berdasarkan hasil uji analisa regresi denganmetode enter diperoleh nilai R2 = 0,257 yang menunjukkan bahwa variabel dukungan sosial teman sebaya dan optimisme berkontribusi sebesar 25,7%terhadap varibel subjective well being.
PENGARUH ANTARA BUDAYA ORGANISASI DAN KOMITMEN ORGANISASI DENGAN KINERJA KARYAWAN DI PT. MASAJI TATANAN KONTAINER INDONESIA
Authors: Al Ghifari Adam , Wibawanti Inayah
Published: November 2022

Penelitian ini merupakan penelitian kuantitatif yang bertujuan untuk menguji pengaruh antarabudaya organisasi dan komitmen organisasi dengan kinerja karyawan di PT. Masaji Tatanan KontainerIndonesia. Sampel pada penelitian ini berjumlah 97 subjek dengan metode pengambilan datamenggunakan Teknik non probability sampling yaitu sampel jenuh. Teknik penentuan sampelbila semua populasi digunakan sebagai sampel. Hal ini sering dilakukan bila jumlah populasirelatif kecil. Istilah lain dari sampel jenuh adalah sensus, maksudnya adalah semua populasidijadikan sampel. Alat ukur yang digunakan adalah skala kinerja (20 item, α = 0,890), skala budayaorganisasi (32 item, α = 0,950), skala komitmen organisasi (20 item, α = 0,928). Hasil penelitian inimenunjukkan terdapat pengaruh positif yang signifikan antara budaya organisasi dengan kinerjakaryawan sebesar 0,762, dan terdapat pengaruh positif yang signifikan antara komitmen organisasidengan kinerja karyawan sebesar 0,551. Selanjutnya, hasil analisis data regresi linear gandamenggunakan program komputer SPSS (Statical Product and Service Solution) versi 22.0 for windowsdiperoleh koefisien korelasi R = 0,773.
Análisis de la propuesta culinaria de la provincia del guayas y su influencia en el desarrollo del turismo gastronómico ecuatoriano. Caso de estudio: 2021-2022
Authors: Norma Susana Sigcho Veloz , López Brunett Ana Luisa
Published: November 2022

La provincia del Guayas-Ecuador es una provincia rica en su variedad gastronómica. El plátano verde, maní, yuca, maíz, mariscos y variedades de carnes son algunos de los ingredientes principales que deleitan el paladar de nativos y turistas. A pesar de la importancia gastronómica en el turismo ecuatoriano, esta provincia tiene falencias marcadas, especialmente porque se ha descuidado en identificar factores que se constituyen en atractivos turísticos. La ausencia de estudios impide impulsar y mejorar las opciones gastronómicas, dando como resultado el lento desarrollo turístico culinario de esta provincia. El presente trabajo, permitirá establecer cómo la intervención de entidades públicas y privadas influye en la promoción de las “huecas gastronómicas”. Así también, analizar los resultados de encuestas a la población de los 25 cantones para concluir que la existencia de un inventario gastronómico permitirá ampliar la oferta gastronómica, satisfacer las exigencias de los turistas; y reconocer como la falta de producto turístico impide el desarrollo social, económico y cultural de la provincia del Guayas; a través de encuestas a la población de los veinte y cinco cantones de la provincia del Guayas.
Políticas macroeconômicas baseadas em evidências são possíveis? A difícil relação da macroeconomia com as evidências empíricas
Authors: Fiani Ronaldo
Published: November 2022

Aborda a evolução e o papel dos modelos econométricos nas primeiras décadas do século XX, como instrumento de análise e comparação de políticas macroeconômicas baseadas em evidências. Discorre sobre a crítica de Lucas (1976), o maior desafio teórico lançado a esse tipo de abordagem empírica. Discute a crítica de Summers (1991), voltada principalmente aos modelos estruturais que foram desenvolvidos a partir da crítica de Lucas (1976). Também aborda a crítica de Romer aos modelos econométricos mais recentes, cuja complexidade muitas vezes impede uma avaliação precisa do valor dos seus resultados, o que é frequentemente agravado pela manipulação dos parâmetros por parte do analista. Examina as possibilidades de uma macroeconomia mais baseada em evidências, à luz do que foi discutido nas seções anteriores.
E o nível subnacional? Os (não) usos das políticas informadas por evidências na política educacional estadual brasileira
Authors: Segatto Catarina Ianni , Santos Fernando Burgos Pimentel dos , Alves Mario Aquino , Peria Pedro
Published: November 2022

Este capítulo busca compreender em maior profundidade como as evidências são usadas no processo decisório a partir de uma análise da política de educação nos estados brasileiros, com ênfase para a experiência do estado de São Paulo. O caso de São Paulo foi analisado em maior profundidade, pois este é o único estado em que houve a institucionalização do uso de evidências no processo decisório na Secretaria da Educação do Estado de São Paulo, que ocorreu a partir da criação de um órgão específico para a produção e o uso de evidências nessa política, o chamado Escritório de Evidências. A análise está dividida em três partes: i) análise documental, usando os websites das 27 secretarias estaduais de educação; ii) análise documental dos planos estaduais de educação; e iii) entrevistas semiestruturadas com gestores e ex-gestores da Secretaria da Educação do Estado de São Paulo.
INTEGRAL MODEL OF COVID-19 SPREAD AND MITIGATION IN UK: IDENTIFICATION OF TRANSMISSION RATE
Authors: Hritonenko Natali , Satsky Caroline , Yatsenko Yuri
Published: November 2022

The integral model with finite memory is employed to analyze the timeline of COVID-19 epidemic in the United Kingdom and government actions to mitigate it. The model uses a realistic infection distribution. The time-varying transmission rate is determined from Volterra integral equation of the first kind. The authors construct and justify an efficient regularization algorithm for finding the transmission rate. The model and algorithm are approbated on the UK data with several waves of COVID-19 and demonstrate a remarkable resemblance between real and simulated dynamics. The timing of government preventive measures and their impact on the epidemic dynamics are discussed.
NGC 6153: Reality is Complicated*
Authors: Richer Michael G. , Arrieta Anabel , Arias Lorena , Castañeda-Carlos Lesly , Torres-Peimbert Silvia , López José Alberto , Galindo Adolfo
Published: November 2022

We study the kinematics of emission lines that arise from many physical processes in NGC 6153 based upon deep, spatially resolved, high-resolution spectra acquired with the UVES spectrograph at the European Southern Observatory Very Large Telescope. Our most basic finding is that the plasma in NGC 6153 is complex, especially its temperature structure. The kinematics of most emission lines defines a classic expansion law, with the outer part expanding fastest (normal nebular plasma). However, the permitted lines of O i, C ii, N ii, O ii, and Ne ii present a constant expansion velocity that defines a second kinematic component (additional plasma component). The physical conditions imply two plasma components, with the additional plasma component having lower temperature and higher density. The [O ii] density and the [N ii] temperature are anomalous, but may be understood considering the contribution of recombination to these forbidden lines. The two plasma components have very different temperatures. The normal nebular plasma appears to have temperature fluctuations in part of its volume (main shell), but only small fluctuations elsewhere. The additional plasma component contains about half of the mass of the N2+ and O2+ ions, but only 3%–5% of the mass of H+ ions, so the two plasma components have very different chemical abundances. We estimate abundances of

12
+
log
(

O

2
+

/

H

+

)
∼
9.2

dex and He/H ∼ 0.13. Although they are all complications, multiple plasma components, temperature fluctuations, and the contributions of multiple physical processes to a given emission line are all part of the reality in NGC 6153, and should generally be taken into account.
Solar-cycle-related Variation of Differential Rotation of the Chromosphere
Authors: Wan Miao , Gao Peng-xin
Published: November 2022

Solar-cycle-related variation of the solar chromospheric rotation is studied by analyzing the chromospheric rotation rate of 938 synoptic maps generated from the Ca ii K line at the Mount Wilson Observatory during the period of 1915 August 10 to 1985 July 7. The results obtained are as follows: (1) The parameters A (the equatorial rotation rate) and B (the latitudinal gradient of rotation) in the standard form of differential rotation both show a decreasing trend in the considered time frame, although A has weak statistical significance. (2) There is a significant negative correlation between the level of solar activity and parameter B, indicating that there seems to be a correlation between field strength and chromospheric differential rotation. (3) During solar cycles 15, 16, 19, 20, and 21, the southern hemisphere rotates faster, whereas in cycles 17 and 18, the northern hemisphere rotates faster. (4) There exists a significant negative correlation between the N–S asymmetry of the chromospheric rotation rate and that of solar activity, indicating that differential rotation of the chromosphere seems to be strengthened by stronger magnetic activity in a certain hemisphere. Possible explanations for the above results are given.
X-Ray Reverberation Mapping of Ark 564 Using Gaussian Process Regression
Authors: Lewin Collin , Kara Erin , Wilkins Dan , Mastroserio Guglielmo , García Javier A. , Zhang Rachel C. , Alston William N. , Connors Riley , Dauser Thomas , Fabian Andrew , Ingram Adam , Jiang Jiachen , Lohfink Anne , Lucchini Matteo , Reynolds Christopher S. , Tombesi Francesco , Klis Michiel van der , Wang Jingyi
Published: November 2022

Ark 564 is an extreme high-Eddington narrow-line Seyfert 1 galaxy, known for being one of the brightest, most rapidly variable soft X-ray active galactic nuclei (AGN), and for having one of the lowest temperature coronae. Here, we present a 410 ks NuSTAR observation and two 115 ks XMM-Newton observations of this unique source, which reveal a very strong, relativistically broadened iron line. We compute the Fourier-resolved time lags by first using Gaussian processes to interpolate the NuSTAR gaps, implementing the first employment of multitask learning for application in AGN timing. By simultaneously fitting the time lags and the flux spectra with the relativistic reverberation model reltrans, we constrain the mass at

2.3

−
1.3

+
2.6

×

10

6

M

⊙

, although additional components are required to describe the prominent soft excess in this source. These results motivate future combinations of machine learning, Fourier-resolved timing, and the development of reverberation models.
Optical Variability of Eight FRII-type Quasars with 13 yr Photometric Light Curves
Authors: Kuźmicz Agnieszka , Goyal Arti , Zola Stanisław , Jamrozy Marek , Dróżdż Marek , Ogłoza Waldemar , Siwak Michał , Reichart Daniel E. , Kouprianov Vladimir V. , Caton Daniel B.
Published: November 2022

We characterize the optical variability properties of eight lobe-dominated radio quasars (QSOs): B2 0709+37, FBQS J095206.3+235245, PG 1004+130, [HB89] 1156+631, [HB89] 1425+267, [HB89] 1503+691, [HB89] 1721+343, and 4C +74.26, systematically monitored for a duration of 13 yr since 2009. The quasars are radio-loud objects with extended radio lobes that indicate their orientation close to the sky plane. Five of the eight QSOs are classified as giant radio quasars. All quasars showed variability during our monitoring, with magnitude variations between 0.3 and 1 mag for the least variable and the most variable QSOs, respectively. We performed both structure function (SF) analysis and power spectral density (PSD) analysis for the variability characterization and search for characteristic timescales and periodicities. As a result of our analysis, we obtained relatively steep SF slopes (α ranging from 0.49 to 0.75) that are consistent with the derived PSD slopes (∼2–3). All the PSDs show a good fit to single power-law forms, indicating a red-noise character of variability between timescales of ∼13 yr and weeks. We did not measure reliable characteristic timescales of variability from the SF analysis, which indicates that the duration of the gathered data is too short to reveal them. The absence of bends in the PSDs (change of slope from ≥1 to ∼0) on longer timescales indicates that optical variations are most likely caused by thermal instabilities in the accretion disk.
Has JWST Already Falsified Dark-matter-driven Galaxy Formation?
Authors: Haslbauer Moritz , Kroupa Pavel , Zonoozi Akram Hasani , Haghi Hosein
Published: November 2022

The James Webb Space Telescope (JWST) discovered several luminous high-redshift galaxy candidates with stellar masses of M
* ≳ 109
M
⊙ at photometric redshifts z
phot ≳ 10, which allows to constrain galaxy and structure formation models. For example, Adams et al. identified the candidate ID 1514 with

log

10

(

M

*

/

M

⊙

)
=

9.8

−
0.2

+
0.2

located at

z

phot

=

9.85

−
0.12

+
0.18

and Naidu et al. found even more distant candidates labeled as GL-z11 and GL-z13 with

log

10

(

M

*

/

M

⊙

)
=

9.4

−
0.3

+
0.3

at

z

phot

=

10.9

−
0.4

+
0.5

and

log

10

(

M

*

/

M

⊙

)
=

9.0

−
0.4

+
0.3

at

z

phot

=

13.1

−
0.7

+
0.8

, respectively. Assessing the computations of the IllustrisTNG (TNG50-1 and TNG100-1) and EAGLE projects, we investigate if the stellar mass buildup as predicted by the ΛCDM paradigm is consistent with these observations assuming that the early JWST calibration is correct and that the candidates are indeed located at z ≳ 10. Galaxies formed in the ΛCDM paradigm are by more than an order of magnitude less massive in stars than the observed galaxy candidates implying that the stellar mass buildup is more efficient in the early universe than predicted by the ΛCDM models. This in turn would suggest that structure formation is more enhanced at z ≳ 10 than predicted by the ΛCDM framework. We show that different star formation histories could reduce the stellar masses of the galaxy candidates alleviating the tension. Finally, we calculate the galaxy-wide initial mass function (gwIMF) of the galaxy candidates assuming the integrated galaxy IMF theory. The gwIMF becomes top-heavy for metal-poor star-forming galaxies decreasing therewith the stellar masses compared to an invariant canonical IMF.
Quick-look Pipeline Light Curves for 5.7 Million Stars Observed Over the Second Year of TESS’ First Extended Mission
Authors: Kunimoto Michelle , Tey Evan , Fong Willie , Hesse Katharine , Shporer Avi , Fausnaugh Michael , Vanderspek Roland , Ricker George
Published: November 2022

We present High-Level Science Products (HLSPs) containing light curves from MIT's Quick-Look Pipeline (QLP) from the second year of Transiting Exoplanet Survey Satellite (TESS’) first Extended Mission (Sectors 40–55; 2021 July–2022 September). In total, 12.2 million per-sector light curves for 5.7 million unique stars were extracted from 10 minutes cadence Full-Frame Images (FFIs) and are made available to the community. As in previous deliveries, QLP HLSPs include both raw and detrended flux time series for all observed stars brighter than TESS magnitude T = 13.5 mag. Starting in Sector 41, QLP also produces light curves for select fainter M dwarfs. QLP has provided the community with one of the largest sources of FFI-extracted light curves to date since the start of the TESS mission.
Ramaria barenthalensis a new record from Western Himalayas, Kashmir
Authors: Ullah Tariq , Firdous Syeda , Khalid Abdul Nasir
Published: November 2022

The genus Ramaria is a globally distributed genus inhabiting different substrates. In the present study samples of Ramaria barenthalensis, were collected during a fungal survey from Neelum Valley, Azad Jammu and Kashmir, Pakistan. Identification was carried out through combined morpho-anatomical and nuclear ribosomal DNA internal transcribed spacer (ITS) sequence analysis that confirmed its position as Ramaria barenthalensis. The taxon is a new record to fungi of Kashmir, Pakistan.
Recognising institutional context in simulating and generalising exchange values for monetary ecosystem accounts
Authors: Barton David N.
Published: November 2022

The paper argues that monetary valuation of ecosystem services for ecosystem accounting needs to be sensitive to institutional context, when simulating markets to generate exchange values where none was available previously and when conducting value generalisation that extrapolates exchange values from specific sites to the whole acounting area. The same ecosystem type can contain different governance regimes or, conversely, a single governance regime may be present in many ecosystem types. Governance regimes are, in part, determined by ecosystem type and condition, but also by ecosystem access characteristics which vary over urban-rural gradients. An ecosystem service will not have a single price if costs of supply and transaction vary in space. This is generally true for all accounting compatible valuation methods if they are extrapolated across different market contexts, but require particular attention if markets are simulated for specific locations and then assumed to be generally valid for the accounting area. The paper exemplifies this for different institutional settings for exchange values of recreation services exploring the general recommendation in SEEA EA for making valuation methods sensitive to institutional context. Stated preference methods simulate markets for ecosystem services. The paper then reviews non-market stated preference valuation studies that have been sensitive to institutional design. Findings on institutional design are, therefore, specifically relevant for simulation of market exchange values for the purpose of compiling monetary ecosystem accounts. The paper finds that disregard for the institutional context in valuation for ecosystem accounting can lead to: (i) errors of generalisation/aggregation and (ii) downward ‘bias’ in simulated accounting prices (relative to the status quo of the institutional context).
On the detection of patterns in electricity prices across European countries: An unsupervised machine learning approach
Authors: Saligkaras Dimitrios , Papageorgiou Vasileios E.
Published: November 2022

The year 2022 is characterized by a generalized energy crisis, which leads to steadily increasing electricity prices around the world, while the corresponding salaries remain stable. Therefore, examining trends in electricity prices relative to existing income levels can provide valuable insights into the overpricing/underpricing of energy consumption. In this article, we examine the tendencies of 35 European countries according to their national kWh prices and the average household incomes. We use a series of established clustering methods that leverage available information to reveal price and income patterns across Europe. We obtain important information on the balance between family earnings and electricity prices in each European country and are able to identify countries and regions that offer the most and least favorable economic conditions based on these two characteristics studied. Our analysis reveals the existence of four price and income patterns that reflect geographical differences across Europe. Countries such as Iceland, Norway, and Luxembourg exhibit the most favorable balance between prices and earnings. Conversely, electricity prices appear to be overpriced in many southern and eastern countries, with Portugal being the most prominent example of this phenomenon. In general, average household incomes become more satisfactory for European citizens as we move from east to west and south to north. In contrast, the respective national electricity prices do not follow this geographical pattern, leading to notable imbalances. After identifying significant cases of inflated prices, we investigate the respective causes of the observed situation with the aim of explaining this extreme behavior with exogenous factors. Finally, it becomes clear that the recent increase in energy prices should not be considered as a completely unexpected event, but rather as a phenomenon that has occurred and developed gradually over the years.
Learning Management Systems, Education Technology Advancement, Successes Adoption of Delone-McLean Model Approaches
Authors: Ibrahim Fahmi , Abdullah Jessica , Susanto Heru , Subramanian Ulaganathan
Published: November 2022

The education system has been greatly impacted due to the coronavirus disease 2019 (COVID-19) which was first reported on 3 0th January 2020 by World Health Organisation (WHO). This leads many to adopt and inculcate online learning and learning management systems for blended learning. The aim of this chapter is to study the success of using Moodle Learning Management System that is used among the students and lecturers in University Technology Brunei using the updated DeLone and McLean Information System Success Model. This study employs a mixed methods approach that comprises of both qualitative (through semi-structured interviews) and quantitative methods (collected using the adapted instruments from D&M 2003 Model). The outcome of the research shows support and validation of the adapted model and instruments. System quality and information quality were identified to be the constructs to determine the overall success.
A Review of Literature on Methods for Teaching and Learning Programming in High Schools
Authors: Salleh Faridah Hani Mohamed , Redzuan Nurul Azlin Liyana Mohamad , Salleh Noor Saliza Mohd
Published: November 2022

Programming is arguably one of the most important skills for current as well as future generations to learn. The digital jobs market continues to develop at a rapid rate, with each year more skilled coders in demand. Learning coding should start from an early stage. Recently, many schools have started to teach programming to high school students. However, according to the authors' observations, comparatively less attention has been paid to reviewing the methodologies particularly at high school level. In this chapter, the authors carry out an in-depth qualitative study of the most important research works in this context by discussing strengths and limitations of existing approaches. They also study the possibility of the methods to be applied by public schools in Malaysia by considering the factors of language of communication, implementation and execution, digital divide and teaching and learning time. These reviews are useful to educators and any organization that intends to formulate co-curriculum and propose learning techniques.
Hybrid Architecture Based on Blockchain Technology and Smart Contracts for Healthcare Applications
Authors: Meftah Mohammed Charaf Eddine , Cherif Cherif Ahmed , Meraghni Belgacem , Berdjouh Chafik
Published: November 2022

The goal of this paper is to design a hybrid architecture based on blockchain technology and smart contracts for healthcare applications. The problem that will be addressed is how to achieve a balance between the three standard concepts of the success of the health system, which are: “privacy,” “security,” and “efficiency and effectiveness of data usage.” The authors proposed a hybrid architecture for a more balanced approach by storing the light information in the blockchain (distributed and decentralized storage), except for large media files, which are in the central storage, which reduces the cost of storing large files and raises the protection of critical information. For demonstration, an application was developed based on the proposed architecture and using smart contracts with the help of an IPFS server as a document storage method, and using MetaMask application as an authentication tool.
C-HUIM
Authors: Sagare Sandipkumar Chandrakant , Kodavade Dattatraya Vishnu
Published: November 2022

High-utility itemset mining is one of the highly researched area. Many research enthusiasts have discovered various techniques and algorithms to mine high-utility itemsets from transaction databases. One of the limitations of the existing high-utility itemset mining techniques is that there is no any generalized framework for applying the custom combinations of input parameters and any other constraints for mining high utility itemsets. This paper proposes a novel customizable framework to discover customized high utility itemsets (C-HUI). Users can customize the constraints and/or input parameters as per their requirements. A novel C-HUIM algorithm is used to discover customized high utility itemsets (C-HUI) from real-life datasets. The experimental results of the proposed framework and C-HUIM algorithm highlight the effectiveness of the approach.
Factors Affecting the Success of Social Commerce in Kuwaiti Microbusinesses
Authors: Al-Qirim Nabeel , Rouibah Kamel , Abbas Hasan , Hwang Yujong
Published: November 2022

Many studies have focused on the adoption of social commerce (s-commerce) by customers but not by businesses or by microbusinesses. Further, they have investigated this adoption from a researcher's perspective while using quantitative approaches. To fill this gap, the study sheds light on the success of Instagram for microbusinesses (IMB) in an Arab country and highlights the need for more investigation in order to understand this complex phenomenon. In this study, the authors use a qualitative approach to 27 microbusiness cases that adopted Instagram for s-commerce. They use technological innovation theories to successfully identify and classify the drivers and inhibitors of success under different contexts. Hence, they find that the success of IMB in Kuwait is contingent on addressing different technological, organizational, and environmental challenges. Further, they find that Instagram initiatives are still evolving and still need assistance from different stakeholders to overcome several hurdles. This study provides different recommendations that advance the theory and practice.
An empirical analysis of the twin deficit hypothesis: the case of Sri Lanka
Authors: Jayasundara J. M. D. P. , Fernando P. J. S.
Published: November 2022

Prolonged fiscal deficit is one of the leading causes behind many economic disruptions in a country, including current account imbalances. Hence, the purpose of this study is to examine the existence of the Twin Deficit Hypothesis (TDH) in Sri Lanka from 1977 to 2020 and to test the validity of Keynesian and Ricardian views in the Sri Lankan context. Using Autoregressive Distributed Lag (ARDL) model, the study found a short-run and long-run relationship between budget and current account deficit. The empirical results support the Keynesian proposition, thus revealing unidirectional causation from the budget deficit to the current account deficit in Sri Lanka. Further, the study found that the short-run relationship between budget deficit and current account deficit is smaller than the long-run effect. Accordingly, Sri Lanka could reduce the current account imbalances using appropriate fiscal reforms designed to reduce the fiscal deficit.
Effects of non-tariff measures on tea exports from Sri Lanka
Authors: Pushpakumara A. B. A. W. , Dissanayake S. N. , Perera S. M. S. D.
Published: November 2022

This study employed the gravity model of trade to examine the effects of non-tariff measures (NTMs) on Sri Lankan tea exports. The study used a panel data set including bilateral exports retrieved from Sri Lanka and its ten major tea export destinations from 2010 to 2019. The frequency of NTMs on Sri Lankan value of tea exports shows an increasing trend. The gravity model estimations show that except for tariff, the coefficients of all other gravity variables are statistically significant and aligned with theoretical justifications. The magnitude of the gross domestic product of Sri Lanka and importer countries and the presence of colonial links positively act on tea exports from Sri Lanka, while the distance between capital cities of trading partners and NTMs lower the exports. More specifically, imposing an additional NTM diminishes the value of tea exports by 48%. Furthermore, the NTMs have a 66% tariff equivalent effect. Hence, Sri Lanka's best prospects for profiting from tea exports depend on altering NTM policies, which are just as significant as other trade barriers.
Is there a gender wage differential even among the most highly educated?
Authors: Rathnasekara H.
Published: November 2022

Even though gender wage discrimination is an extensively discussed topic, many questions remain unanswered, especially concerning the most highly skilled worker groups. This study estimates the gender wage differential of the most highly educated workers - PhD holders - in the United States. The findings suggest a gender wage gap of 17% and 21%, respectively, in 2013 and 2019. The wage differential was decomposed into observed and unobserved portions using the Oaxaca-Blinder decomposition method. The unobserved gender wage differential was 5% and 12%, respectively, in 2013 and 2019. The unexplainable portion of the wage gap was higher in the business/industry sector compared to the academic sector. Among the observed characteristics, less experience appeared to be a major factor for lower wages among women. Further, the results suggest that even highly educated women earned less than their male counterparts, partly due to occupational segregation – job category, employment category, and the field of study contributed to more than 40% of the observed wage gap in the business/industry sector.
Modelling the Impact of COVID-19 on SMEs’ Performance: Econometrics Evidence from Sri Lanka
Authors: Deyshappriya N. P. Ravindra , Padmakanthi N. P. D.
Published: November 2022

COVID-19 has created severe health issues while creating drastic impacts on global economy and thus the World Health Organization (WHO) announced a global emergency condition as well. These adverse impacts of COVID-19 are more substantial especially in business sectors in least developed and developing countries. Hence, the current study attempts to examine the impact of COVID-19 on SMEs’ performance in Sri Lanka, highlighting the differences in SMEs’ performance between pre-COVID-19 and during COVID-19 periods. The study based on primary data collected from 304 SMEs located in nine provinces of Sri Lanka and both descriptive and econometrics analyses were employed to accomplish the objectives of the study. The statistical investigation based on t-test analysis clearly indicates that there is a statistically significant difference in SMEs’ performance between pre-COVID-19 and during COVID-19 periods. More specifically, both financial and operational performance have reduced while increasing the innovative performance during the COVID-19 period compared to Pre-COVID-19 period. Moreover, the econometrics analysis confirms that SMEs affected by COVID-19 account for lower performance compared to those are not affected by COVID-19. More specifically, negative impact on SMEs performance gets higher when the magnitude of COVID-19 impacts increases. Hence, it is apparent that COVID-19 has drastically affected the SMEs’ performance in Sri Lanka. Thus, the present study strongly recommends implementation of proactive policies to re-emerge SMEs while SMEs should themselves organize to battle with the COVID-19 outbreak.
A Prospective Study to Determine the Incidence, Clinical Profile, and Outcomes of Patients with Ventilator-Associated Pneumonia
Authors: Bhattacharjee Sagnik , Khyriem Annie B. , Lyngdoh Clarissa Jane , Prasad Abhijit Kumar
Published: November 2022

Objective:

The objective was to determine the incidence, etiological agents, and antibiotic susceptibility pattern of isolates causing ventilator-associated pneumonia (VAP).

Methods:

The prospective observational study was carried out on 146 adults admitted to the hospital, who were put on mechanical ventilation for a minimum period of 48 h at NEIGRIHMS, Shillong. The study was conducted for 1 year from December 2019 to December 2020. VAP was diagnosed as per the Clinical Pulmonary Infection Score. Demographic, clinical characteristics, culture reports, and antibiotic susceptibility of the patients were noted. Patients were followed up till discharge or death. Outcome measures were risk factors for VAP and mortality.

Results:

We report an incidence of VAP as 10.6/1000 ventilator days. The predominant organisms seen were Acinetobacter baumannii (62.33%), Klebsiella pneumoniae (47.26%), and Pseudomonas aeruginosa (19.18%). 33/146 (22.6%) patients expired, among which 17 patients had VAP (40.48% vs. 15.38%, P = 0.001). VAP patients had significantly higher odds of smoking (odds ratio [OR] = 2.412, P = 0.016), more polybacterial infections (OR = 2.271, P = 0.024), and more mortality (OR = 3.681, P = 0.001). Among the organisms, P. aeruginosa (OR = 0.115, P = 0.013) and K. pneumoniae (OR = 6.818, P = 0.003) were significantly associated with mortality in patients with VAP.

Conclusion:

We report an incidence of VAP as 10.6/1000 ventilator days among intensive care unit patients. Smoking was a significant risk factor for VAP. VAP patients had a significantly higher risk of mortality with K. pneumoniae and P. aeruginosa being significant organisms responsible for it.
Serological screening of celiac disease in children and adolescents with juvenile idiopathic arthritis
Authors: Abdelgalil Abobakr A. , Tarek Sara
Published: November 2022

Background

Patients with juvenile idiopathic arthritis (JIA) seem to be at higher risk of developing immune-mediated diseases like celiac disease (CD) than general population.

Aim

The aim of this study was to detect the prevalence of CD among children and adolescents with JIA.

Patients and methods

We carried out a cross-sectional study that included 42 JIA patients under the age of 16 years. In addition to demographic, clinical, and laboratory data, anti-tissue transglutaminase immunoglobulin A (anti-TTG IgA) antibodies were measured using a novel chemiluminescent immunoassay.

Results

Only one (2.4%) patient had positive anti-TTG IgA. There was no significant correlation between anti-TTG IgA and terms of growth parameters, JIA subtype, or medications.

Conclusion

JIA patients seem to be at higher risk to develop CD. Being mostly asymptomatic, they should be candidates for periodic screening. Methodologically standardized larger studies are recommended to reach a cost-effective protocol for monitoring JIA patients regarding the development of CD, adding to early diagnosis and control of the disease.
Relevance of Charaka's Principles for Psychological Well-Being during the COVID Pandemic
Authors: Chandhok Sonam , Shubhashree M. N. , Chandrasekharan Chandini
Published: November 2022

The coronavirus pandemic has created a psychological havoc across nations. Researchers and mental health practitioners have put in their efforts to use contemporary forms of psychological interventions and therapies for the management of mental health concerns that have arisen in the current pandemic. However, only rare attention has been paid to the principles of Ayurveda for psychological issues. Hence, the present paper aims to bring forth the forgotten but treasured principles of Ayurveda explicated in Charaka Samhita for psychological well-being and to outline some of the indigenous strategies for COVID-related psychosocial management.