bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effects of Vit E and Vit C Use on Ovarian Surface Epithelium and Follicle Reserve in Autologous Intraperitoneal Ovarian Transplantation in Rats: An Experimental Study
Authors: Sapmaz Tansel , Kale Ebru , Pence Halime Hanim , Sevgin Kubra , Tekayev Muhammetnur , Topkaraoglu Sude , Basol Gulfem , Yilmaz Muserref Banu , Sapmaz Ekrem , Irkorucu Oktay
Published: November 2021

Purpose: The aim of this study was to investigate the effects of vitamin E (Vit E) and vitamin C (Vit C) on oxidant-antioxidant system markers, ovarian follicle reserves, and surface epithelium in autologous intraperitoneal ovarian transplantation in rats.Materials and Methods: 20 adult female Wistar Albino were randomly divided into four groups. Group 1 (n = 5), the control group, only had their abdomens opened and closed. Group 2 (n = 5): underwent an ovarian transplantation. Group 3 (n = 5) received 20 mg/kg of intraperitoneal (IP) Vit E 15 minutes before an ovarian transplantation. Group 4 (n = 5) received 50 mg/kg of IP Vit C that was administered 15 minutes before an ovarian transplantation.Vaginal cytology was performed to monitor the oestrus phase. Biochemically, tissue and serum malondialdehyde levels and erythrocyte superoxide dismutase (SOD) levels were measured. Histopathologically, the number dysplastic changes in the ovarian surface epithelium were examined. Results: Dysplastic changes in the surface epithelium of Group 2 were found to be significantly higher than in Group 1 and 4 (p < 0.02). In Group 2, the ovarian follicle reserves were significantly lower than in other groups (p < 0.02). In addition, a significant decrease in SOD levels was found in Group 2 compared to other groups (p < 0.02). Conclusion: The study showed that Vit E and Vit C in autologous intraperitoneal ovarian transplantation preserved the ovarian follicle reserve. Vit C was found to be more effective than Vit E.
Tracking genetic diversity of SARS-CoV-2 infections in Ghana after one year of surveillance
Authors: Morang'a Collins , Ngoi Joyce , Gyamfi Jones , Amuzu Dominic , Nuertey Benjamin , Soglo Philip , Appiah Vincent , Asante Ivy , Owusu-Oduro Paul , Armoo Samuel , Adu-Gyasi Dennis , Amoako Nicholas , Oliver-Commey Joseph , Owusu Michael , Sylverken Augustina , Fenteng Edward , M'cormack Violette , Tei-Maya Frederick , Quansah Evelyn , Ayivor-Djanie Reuben , Amoako Enock , Ogbe Isaac , Yemi Bright , Osei-Wusu Israel , Mettle Deborah , Saiid Samirah , Tapela Kesego , Dzabeng Francis , Magnussen Vanessa , Quaye Jerry , Opurum Precious , Carr Rosina , Ababio Patrick , Abass Abdul-Karim , Akoriyea Samuel , Amoako Emmanuella , Kumi-Ansah Frederick , Boakye Oliver , Mibut Dam , Odoom Theophilus , Ofori-Boadu Lawrence , Allegye-Cudjoe Emmanuel , Dassah Sylvester , Asoala Victor , Asante Kwaku Poku , Phillips Richard , Osei-Atweneboana Mike , Gyapong John , Kuma-Aboagye Patrick , Ampofo William , Duedu Kwabena , Ndam Nicaise , Bediako Yaw , Quashie Peter , Amenga-Etego Lucas , Awandare Gordon
Published: November 2021

This study sequenced 1077 SARS-CoV-2 genomes from patient isolates (106 from arriving travellers and 971 from communities) to track the molecular evolution and spatio-temporal dynamics of the SARS-CoV-2 variants in Ghana. The data show that initial local transmission was dominated by B.1.1 lineages, but the second wave in Ghana was overwhelmingly driven by the Alpha variant, which was detected in community cases from January 2021, with Eta also contributing to reported cases. Subsequently, an unheralded variant under monitoring, B.1.1.318, dominated transmission from April to June 2021 before being displaced by Delta (B.1.1.617) and Delta Plus (AY.*) variants, which were introduced into community transmission in May 2021 and have remained dominant to date. Mutational analysis indicated that variants that took hold in Ghana harboured transmission enhancing and immune escape spike substitutions. The apparent rapid viral evolution observed demonstrate the potential for emergence of novel variants with greater mutational fitness.
Pan-Cancer Analyses of Pyroptosis With Functional Implications in Prognosis and Immunotherapy in Cancer
Authors: Liu Aibin , Shen Lin , Li Na , Shen Liangfang , Li Zhanzhan
Published: November 2021

Background
Programmed cell death is an active and orderly form of cell death regulated by intracellular genes, which plays an important role in the normal occurrence and development of the immune system, and pyroptosis has been found to be involved in the tumorigenesis and development. However, compressive analysis and biological regulation about pyroptosis genes are lack in cancers.
Methods
Using the data from the The Cancer Genome Atlas, we established a score level model to quantify the pyroptosis level of cancer. Multi-omics bioinformatical analyses was performed to detect pyroptosis-related molecular features and effect of pyroptosis on immunotherapy in cancer.
Results
In the present study, we performed a comprehensive analysis of pyroptosis and its regulator genes in cancers. Most pyroptosis genes were aberrantly expressed among different cancer types, which is contributed by the CAN frequency and differences of DNA methylation level in cancer. We established the modeling of the pyroptosis level and found that pyroptosis showed dual roles across cancers, while the pyroptosis levels were different in multiple and be significantly associated with clinical prognosis. The dual role of pyroptosis also affect the effects of immunotherapy in several cancers. Multiple pyroptosis genes showed close connections with drug sensitivity across cancers, and may be considered as therapy targets in cancer.
Conclusions
Our comprehensive analyses provide new insight into the functions of pyroptosis in the initiation, development, and progression and treatment across cancers, suggesting corresponding prognostic and therapeutic utility.
Photocatalytic Defluoroalkylation and Hydrodefluorination of Trifluoromethyls using o-Phosphinophenolate
Authors: Liu Can , Shen Ni , Shang Rui
Published: November 2021

Under visible light irradiation, o-phosphinophenolate functions as an easily accessible photoredox catalyst to activate trifluoromethyl groups in trifluoroacetamides, trifluoroacetates, and trifluoromethyl (hetero)arenes to deliver corresponding difluoromethyl radicals. It works in relay with a thiol hydrogen atom transfer (HAT) catalyst to enable selective defluoroalkylation and hydrodefluorination. The reaction allows for the facile synthesis of a broad scope of difluoromethylene-incorporated carbonyl and (hetero)aromatic compounds, which are valuable fluorinated intermediates of interest in the pharmaceutical industry. The ortho-diphenylphosphino substituent, which is believed to facilitate photoinduced electron transfer, plays an essential role in the redox reactivity of phenolate. In addition to trifluoromethyl groups, pentafluoroethyl groups could also be selectively defluoroalkylated.
A Method for Quantifying the Role of Carbonate Acid, Sulfuric Acid and Nitric Acid in Carbonate Weathering After Modifying the Effect of Evaporite in Qingjiang Karst Catchment
Authors: He Xinhui , Zhou Hong , Wan Junwei , Zhao Heng , He Shiyi
Published: November 2021

Qingjiang river is the second largest tributary of the Yangtze River in Hubei province, it’s also a typical karst catchment. Eighty-two important groundwater samples were collected during high and low water period of 2019. The results show that: (1) The major hydrochemistry types are Ca+Mg-HCO3 and Ca-HCO3, indicate that carbonate weathering is the main source of groundwater chemistry; (2) The results of inverse hydrochemical modeling show that there are two kinds of groundwater-carbonate rock interactions. One is co-dissolution of calcite and dolomite, the other is dedolomitization, and thereinto, dedolomitization is widespread in dolomite aquifers. Furthermore, gypsum has a tendency to dissolve in each aquifer, and the common ion effect of Ca2+ caused by gypsum dissolution promotes dedolomitization. The modeling results suggest that major elements have a good traceability effect on the material source of groundwater. (3) The chemical weathering of carbonate rock is mainly affected by carbonic acid, sulfuric acid and nitric acid. After modifying the impact of evaporite and atmospheric input, the calculations show that the contribution of carbonic acid involved in carbonate weathering is 70.9% (high water period) and 70.0% (low water period). Through statistics of karst springs discharge and contribution of acid involved in carbonate weathering, the two are in a positive relationship. The result can reflect the laws of sulfuric acid and nitric acid under the hydrodynamic condition in different seasons. Therefore, the carbonate weathering should be carefully evaluated in karst areas which have abundant groundwater and the role of groundwater in carbonate weathering is worthy of further study.
Evaluation of the Performance of CFSR Reanalysis Data Set for Estimating Potential Evapotranspiration (PET) in Turkey
Authors: IRVEM AHMET , OZBULDU Mustafa
Published: November 2021

Evapotranspiration is an important parameter for hydrological, meteorological and agricultural studies. However, the calculation of actual evapotranspiration is very challenging and costly. Therefore, Potential Evapotranspiration (PET) is typically calculated using meteorological data to calculate actual evapotranspiration. However, it is very difficult to get complete and accurate data from meteorology stations in, rural and mountainous regions. This study examined the availability of the Climate Forecast System Reanalysis (CFSR) reanalysis data set as an alternative to meteorological observation stations in the computation of potential annual and seasonal evapotranspiration. The PET calculations using the CFSR reanalysis dataset for the period 1987-2017 were compared to data observed at 259 weather stations observed in Turkey. As a result of the assessments, it was determined that the seasons in which the CFSR reanalysis data set had the best prediction performance were the winter (C'= 0.76 and PBias = -3.77) and the autumn (C' = 0.75 and PBias = -12.10). The worst performance was observed for the summer season. The performance of the annual prediction was determined as C'= 0.60 and PBias = -15.27. These findings indicate that the results of the PET calculation using the CFSR reanalysis data set are relatively successful for the study area. However, the data should be evaluated with observation data before being used especially in the summer models.
Potassium Fertigation to Enhance the Performance of Hypoxis hemerocallidea
Authors: Akakpo Patience Seyram , Sedibe Moosa Mahmood , Zaid Bello , Khetsha Zenzile P. , Theka-Kutumela Mokgaputsiwa P. , Mudau Fhatuwani N.
Published: November 2021

Potassium (K) is an essential nutrient in plant metabolism, ionic balance, and stress resistance. In this study, the effects of K on agronomic attributes and on mineral and primary metabolite content in African potato were determined. K was administered hydroponically at four concentrations (4.00, 6.00, 8.00, and 10.00 meq·L−1) using Steiner’s universal nutrient solution. Chlorophyll content (CHL), leaf area (LA), fresh corm mass (FCM), number of roots (NR), root fresh weight (RFM), and root dry mass (RDM) were measured 18, 32, and 40 weeks after transplanting. Mineral analysis data were collected at 18 weeks, and primary metabolite data were collected at 32 weeks. Significant effects of K were observed after 18 weeks, and all test concentrations had a positive effect on yield. Calcium and boron significantly accumulated in the corm at 4.00 meq·L−1 K. Alanine and malic acid were the only metabolites affected by K concentrations. More minerals accumulated in the corm at 4.00 meq·L−1 K, whereas at 10.00 meq·L−1 K, more minerals clustered in the leaf. K applied at 4.00 meq·L−1 is recommended when growing African potato using a nutrient solution to improve corm mineral and metabolite accumulation.
Antifungal Finishing of Fabrics with Natural Dyes from Aerial Biomass of Perilla frutescens (L.) Britton
Authors: Pal Anita , Kumar Rakesh , Tripathi Yogesh Chandra
Published: November 2021

Increased environmental consciousness coupled with detrimental impacts of synthetic dyes and consumers’ concern over hygiene, cleanliness and protection, the demand for functional textiles has increased in recent years. Antimicrobial finishing imparts protective properties to textiles besides attractive shades. The study was aimed to determine the antifungal activity of colourants from aerial biomass of Perilla frutescens and dyed fabrics against pathogenic fungi infesting textiles materials. Antifungal activity of natural dye extracted from aerial biomass of Perilla frutescens against the selected pathogenic fungi viz., Aspergillus niger, Aspergillus flavus, Fusarium moniliforme, Fusarium solani, and Penicillium decumbens was evaluated by agar-well diffusion method. The MIC of the natural dye against each of the test fungi was determined by broth dilution method. Dyed silk, wool and cotton fabrics were also evaluated for antifungal activity by standard method. The natural dye showed antifungal activity against all the five test fungi in a concentration dependent manner. The treatment dose of 1000μg/ml recorded the highest growth reduction in all the test fungi, nearly at par with the positive control. The MICs of natural dye against the test fungi ranged from 32.39 to 36.50μg/ml. All kinds of dyed fabrics also showed remarkable antifungal efficacy against the test fungi. Dyed wool fabric exhibited the maximum growth reduction followed by silk and cotton. The result of the study demonstrated the remarkable antifungal activity of natural dye from Perilla frutescens aerial biomass and dyed fabrics. Therefore, Perilla frutescens can be considered as a potential source of natural dye with functional properties and can be used in protective finishing of different kinds of textile fabrics.
Acanthamoeba species isolated from marine water in Malaysia exhibit distinct genotypes and variable physiological properties
Authors: Mohd Hussain Rosnani Hanim , Abdul Ghani Mohamed Kamel , Khan Naveed Ahmed , Siddiqui Ruqaiyyah , Anuar Tengku Shahrul
Published: November 2021

The present study identifies the Acanthamoeba genotypes and their pathogenic potential in five marine waters in Malaysia. Fifty water samples were collected between January and May 2019. Physical parameters of water quality were measured in situ, whereas chemical and microbiological analyses were conducted in the laboratory. All samples had undergone filtration using nitrocellulose membrane and were tested for Acanthamoeba using cultivation and polymerase chain reaction by targeting the 18S ribosomal RNA gene. The pathogenic potential of all positive isolates was identified using physiological tolerance tests. Thirty-six (72.0%) samples were positive for Acanthamoeba. Total coliforms (p = 0.013) and pH level (p = 0.023) displayed significant correlation with Acanthamoeba presence. Phylogenetic analysis showed that 27 samples belonged to genotype T4, four (T11), two (T18) and one from each genotype T5, T15 and T20. Thermo- and osmo-tolerance tests signified that three (8.3%) Acanthamoeba strains displayed highly pathogenic attributes. This study is the first investigation in Malaysia describing Acanthamoeba detection in marine water with molecular techniques and genotyping. The study outcomes revealed that the marine water in Malaysia could be an integral source of Acanthamoeba strains potentially pathogenic in humans. Thus, the potential risk of this water should be monitored routinely in each region.
Comprehensive evaluation of the water environment carrying capacity of a river basin: a case study of the Weihe River Basin in China
Authors: Yan Buqing , Wang Yiqi , Li Guoping , Ding Xiaohui
Published: November 2021

By combining the analytic hierarchy process (AHP) and system dynamics (SD) models, a compound index system is established for simulating and evaluating the water environment carrying capacity (WECC) of the Weihe River Basin. The development tendencies of the population, economy, water resource demand and supply, water environment, water pollution, and water management were obtained from 2005 to 2040 by applying the five scenarios designed in this study. The results indicate that the comprehensive solution scenario was the optimal scenario, and the WECC would upgrade from a ‘general’ status to a ‘good’ status. Moreover, the blind pursuit of rapid economic growth is inadvisable, and it will compromise the sustainability of the river basin area. The river basin area should divert local development modes toward increased sustainability, emphasizing the coordinated development of society, the economy, and the environment.
COMPORTAMENTO DA ARRECADAÇÃO PRÓPRIA E DA CARGA TRIBUTÁRIA NOS MUNICÍPIOS DA ZONA DA MATA MINEIRA
Authors: Reis Anderson de Oliveira , Abrantes Luiz Antônio , Faroni Walmer , Passos Natália Leandro dos
Published: November 2021

O processo de descentralização consolidado pela constituição de 1988 mudou a dinâmica do federalismo brasileiro aumentando as receitas disponíveis e também as responsabilidades do fornecimento de serviços para os municípios, que em termos financeiros são muito dependentes das transferências governamentais. Diante da importância dos municípios na Administração Pública como entes federativos, este estudo tem como objetivo identificar, a partir da classificação em grupos, a mudança no perfil da arrecadação tributária própria dos municípios da Zona da Mata Mineira tendo por base os períodos de 2005 e 2010. Trata-se de pesquisa descritiva e quantitativa em que se utilizou as metodologias de Análise de Cluster e Teste t para amostras emparelhadas. Os resultados apontam para formação de 4 grupos de acordo com o esforço fiscal (baixo, médio e alto). Em média observa-se uma evolução positiva na arrecadação própria dos municípios que foi confirmada pelo Teste t. Conclui-se que apesar da dependência dos recursos de transferências, os municípios têm realizados esforços para aumentar a arrecadação própria e consequentemente suas receitas disponíveis.Palavras-Chave: Finanças Públicas. Receita Tributária. Administração Pública.
ESTUDO DAS RELAÇÕES ENTRE SISTEMAS INTEGRADOS DE INFORMAÇÕES E A PRESTAÇÃO DE SERVIÇOS DE ESCRITÓRIO DE CONTABILIDADE EM UMA CIDADE DO ESTADO DE MINAS GERAIS
Authors: De Melo Silva Ávila Jéssica Rayse , Cabral de Ávila Lucimar Antônio
Published: November 2021

A estruturação de um adequado sistema integrado de softwares constitui-se em fator essencial para facilitar a comunicação empresarial, tanto interna quanto externamente, o que pode ocasionar diferenciais em diversos aspectos relativos à concorrência, custos ou ainda nível organizacional. O presente trabalho vislumbra medir se existe relação entre o nível de integração interna e externa dos sistemas de informática e a prestação de serviços em escritórios de contabilidade estabelecidos em uma cidade do interior do estado de Minas Gerais, utilizando como técnica de coleta de dados a aplicação de um questionário. As informações obtidas foram tratadas por meio da utilização do Statistical Package for Social Science (SPSS), o que permitiu traçar conjecturas utilizando-se análises estatísticas descritivas, Correlação de Spearman, Teste de Mann-Whitney e Teste Kruskal Wallis. Como resultados, foi observado que o nível de integração externa é desfavorável e que variáveis como tempo de existência no mercado e forma de constituição profissional não influenciam nos níveis de integração. Por outro lado, constataram-se indícios de influência no nível de integração interna dos sistemas quando há variação no volume de clientes e no volume de faturamento.Palavras-chave: Sistemas integrados. ERP. SI. Prestação de serviços
RELAÇÃO ENTRE FOLGA ORGANIZACIONAL E P&D NAS COMPANHIAS DE ENERGIA ELÉTRICA NA BM&FBOVESPA
Authors: Nez Evandro De , Diel Fabio , Lavarda Carlos Eduardo Facin
Published: November 2021

O presente estudo analisa a relação entre folga organizacional e os gastos com Pesquisa e Desenvolvimento (P&D) nas companhias de energia elétrica listadas na BM&FBovespa. O objetivo da pesquisa é verificar se existe relação entre a folga organizacional e o valor destinado a P&D nestas companhias. A pesquisa é um estudo documental, de caráter descritivo e abordagem quantitativa. Os dados foram coletados nas demonstrações contábeis das empresas, sendo realizada estatística descritiva e posterior análise dos dados em painel. A amostra da pesquisa consiste nas demonstrações financeiras de 22 empresas do setor de energia elétrica entre os anos de 2010 e 2012. Os resultados demonstraram que existe uma relação significativa positiva da variável folga potencial com a aplicação de recursos em P&D, porém, entre folga recuperável e folga disponível e a aplicação de recursos P&D não houve relação significativa. Conclui-se que, quanto mais recursos originados de capital próprio, maior tende a ser a aplicação em P&D nas empresas de energia elétrica.Palavras-chave: Folga Organizacional, P&D, Energia Elétrica.
Classificação Ecodinâmica no campo de dunas de Petrolina - PE
Authors: Cabral Cláudio José
Published: November 2021

O campo de dunas de Petrolina localiza-se na região do Submédio São Francisco em Pernambuco. Ele representa um importante patrimônio geomorfológico e paleoclimático, uma vez que indica a ocorrência de remobilização de sedimento por meio da ação eólica em períodos mais secos durante o Quaternário. Tais oscilações climáticas ocorreram durante o Pleistoceno e Holoceno, tendo estreita relação com o Último Máximo Glacial. A área investigada vem sendo ocupada por vários empreendimentos que ameaçam a estabilidade natural da paisagem. Diante desta realidade, foi desenvolvido um estudo que teve como ponto de partida um trabalho de campo, onde se procedeu a coleta de dados na área. Estes foram processados em laboratório e serviram como subsídio para avaliar o grau de estabilidade da paisagem, com base na Classificação Ecodinâmica de Tricart (1977). A partir desta proposta metodológica foi possível concluir que a paisagem do campo de dunas apresenta diferentes meios morfodinâmicos: Estável, Intergrade e Fortemente Instável, conforme será apresentado no corpo da pesquisa. Estes meios variam conforme o maior ou menor grau de intervenção humana e na manutenção da cobertura vegetal natural, que pode impedir ou impulsionar os processos pedogenéticos ou morfogenéticos, configurando a existência de diferentes arranjos espaciais.
Análise teórica dos conceitos: Riscos Socioambientais, Vulnerabilidade e Suscetibilidade
Authors: Girão Ítalo Renan Ferreira , Rabelo Davi Rodrigues , Zanella Maria Elisa
Published: November 2021

Considerando o conceito de risco e partindo da forma como o homem se organiza e ocupa o espaço, entende-se que a situação de vulnerabilidade e a suscetibilidade estão postas nas diversas realidades, sendo que as características naturais e as condições sociais e econômicas constituem-se elementos variáveis que influenciam na maior ou menor condição dos mesmos. Para realização da determinação dos riscos socioambientais, consolida-se como fundamental a revisão bibliográfica dos conceitos, que, por sua vez, tiveram seu entendimento resignificado nas últimas décadas. Este trabalho propõe-se apresentar a revisão conceitual dos termos expostos no título, a fim de possibilitar um material que sirva como base para o avanço de programas e projetos associados à prevenção de desastres. Dessa forma, os resultados apontam um avanço no estudo de fontes bibliográficas sobre a temática em questão.

 

Palavras-chave: Revisão conceitual; Desastres; Sociedade e meio ambiente.
Registros de desastres associados à estiagem e seca na região do Alto Sertão da Paraíba
Authors: Silva Diêgo Alan Mangueira da , Moura Marcelo de Oliveira
Published: November 2021

Os desastres naturais de ordem climática é um problema histórico na região do semiárido nordestino. A Paraíba é um dos estados brasileiros que mais reconhece desastres de estiagem e seca. Diante desse cenário, buscou-se investigar a frequência dessas ocorrências em uma das regiões de clima semiárido da Paraíba. O objetivo desse artigo é analisar a distribuição espaço-temporal dos desastres deflagrados por estiagem e seca, os quais almejaram decretos por Situação de Emergência (SE) e por Estado de Calamidade Pública (ECP), entre os anos de 2003 a 2016, na região o Alto Sertão da Paraíba. Os dados de reconhecimentos dos desastres foram adquiridos na página do site do Sistema Nacional de Proteção e Defesa Civil (SINPDEC) do Ministério da Integração (MI). Foi contabilizado um total de 503 desastres climáticos na região. Desse montante, 493 foram desastres decretados por SE (485 por estiagem e 8 por seca) e 10 desastres de estiagem decretados por ECP.
Uso de índice espectral para monitoramento da cobertura vegetal no município de Juazeiro do Piauí.
Authors: Amorim dos Santos Francílio de
Published: November 2021

O objetivo do estudo foi realizar uma análise espaço-temporal das condições da cobertura vegetal no município de Juazeiro do Piauí, por meio do índice de vegetação ajustado ao solo (IVAS). Para operacionalização e análise espaço-temporal da cobertura vegetal foram adquiridas imagens da série Landsat, para os anos de 1997, 2006 e 2016. O município estudado apresenta distintas fisionomias para a vegetação do tipo caatinga, que varia do porte herbáceo a arbustivo e arbóreo, além da presença de cerrado rupestre. Os resultados indicaram predomínio das classes de vegetação com atividade fotossintética alta a muito alta nos anos de 1997, ocupando 41,6% do município, e 2006, distribuindo-se por 58,2% da área. Por outro lado, houve significativa redução de ambas as classes em relação ao ano de 2016, quando figurou apenas a classe de atividade fotossintética alta, encontrada em 0,03% do município. Essas mudanças nos padrões fisionômicos da vegetação devem está ligadas à ocorrência dos fenômenos oceânicos El niño e La niña. Desse modo, fica evidente a importância do monitoramento da cobertura vegetal por meio do uso de índices espectrais, visto que a redução da vegetação pode gerar o desencadeamento de processos erosivos e, posterior, desequilíbrios nos sistemas ambientais.
Geodiversidade e Geoconservação do estuário e manguezal rio Potengi: teoria e prática com alunos da Escola Municipal Terezinha Paulino.
Authors: Vieira Ferreira Joyce Clara , Câmara Maciel Ana Beatriz , Lima da Silva Cleanto Carlos , Carvalho Lima Zuleide Maria
Published: November 2021

A educação ambiental serve como uma ferramenta de conscientização e de intervenção, através dela é possível compreender a complexidade dos sistemas ambientais aos quais se está inserido. Diante disso, o objetivo da pesquisa foi trabalhar a temática da Geodiversidade e Geoconservação do estuário e manguezal do rio Potengi junto aos alunos do 8º ano da Escola Municipal Professora Terezinha Paulino de Lima durante a semana do meio ambiente. Além disso, buscou-se discutir os conceitos de Geodiversidade e Geoconservação, apresentar exemplos de geodiversidade e práticas da Geoconservação no Brasil, além de avaliar o entendimento dos alunos mediante às técnicas de ensino utilizadas. Os procedimentos metodológicos utilizados foram: o levantamento bibliográfico acerca da temática da Geodiversidade e da Geoconservação, elaboração de palestra e de duas oficinas voltadas para os alunos; e a realização de trabalho de campo destinado ao estuário e manguezal do rio Potengi, situado na cidade de Natal-RN. Diante disso, ao trabalhar com a temática da Geodiversidade e da Geoconservação de Natal, os alunos puderam conhecer seu município do ponto de vista ambiental e espacial, entender o conceito de Geosiversidade, atentar para importância de conservá-la e desenvolver trabalhos em equipe.
Identificação preliminar dos serviços ecossistêmicos de provisão prestados pelo manguezal no rio Tubarão e no rio Ceará-Mirim (RN - Brasil).
Authors: Cruz Guedes Dayane Raquel da , Félix da Silva Costa Diógenes , Cestaro Luiz Antonio
Published: November 2021

O manguezal proporciona uma série de Serviços Ecossistêmicos (SE) necessários para a manutenção das comunidades humanas que habitam o seu entorno. Esta pesquisa foi realizada em duas áreas de estudo, com enfoque no ecossistema de manguezal em estuários que apresentam condições físicas diferentes, com o objetivo identificar os possíveis serviços ecossistêmicos de provisão prestados pelo ambiente de manguezal no Rio Tubarão, localizado no litoral setentrional do Rio Grande Norte e no manguezal do rio Ceará-Mirim, situado no litoral oriental potiguar. Para a identificação dos SE, foi utilizada a classificação CICES (Common International Standard for Ecosystem Services). Verificou-se que o manguezal desempenha um papel importante para as comunidades locais, que se beneficiam de forma direta e indireta dos bens e serviços prestados.
STATUS OF THE PARODONTIUM TISSUES IN THE CONDITIONS OF LONG-TERM ISOLATION INSIDE AN AIR-TIGHT MODULE
Authors:   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Ilyin V.K. , Rykova M.P. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Antropova E.N. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Solovieva Z.O. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Skedina M.A. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Kovaleva А.А. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Nosovsky А.М. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow
Published: November 2021

The comprehensive investigation of parodontium tissues of the participants in a 120-d isolation study imitating the artificial spacecraft environment was focused on anaerobic microbiota, immunological parameters of the oral liquid and blood flow velocity within the parodentium microcirculation (PMC). Subjects were 6 healthy people (3 males and 3 females) at the age of 29 to 45 years. Parodentium tissues were investigated 14 and 1 day prior to isolation, 3 times in isolation (every 30 days) and on days 1 and 7 after isolation. Qualitative composition of primary pathogens was determined by the polymerase chain reaction (PCR). Concentration of oral immunoglobulins sIgA, IgA, IgМ was measured using the ELISA assay. Blood flow velocity was measured using high-frequency ultrasound Doppler. Our results showed an increase in the immunoglobulins on days 30 and 84 of isolation and subsequent reduction toward the end of the study. The participants were found to be careers of type-1 pathogen Porphyromonas gingivalis and type-2 pathogen Prevotella intermedia. Following isolation, linear indices of the arteriolar blood velocity grew reliably (p < 0.0007); the capillary blood velocity grew by 6.7 % relative to the pre-isolation baseline data. On day 7, capillary perfusion was noted to improve still further. The observed shifts in the local immunity and presence of pathogens point to deterioration of the parodontium defense mechanisms. It appears that activation of inflammatory processes in isolation and confinement remains probable.
CHARACTERISTICS OF THE FUNCTIONING OF MASTICATORY ORGANS AND TISSUES IN FLYING PERSONNEL
Authors:   International Academy of Sciences for Ecology and Nature, Saint-Petersburg, Iordanishvili А.К.
Published: November 2021

The objective data about functioning of chewing organs and tissues were used for comparison between fighter pilots and non-flying personnel. It was found that exposure to the fighter factors affects the sensitivity of oral receptors. Data of electro-odontometry, myotonometry, gnathodynamometry, esthesiometry and electrogustometry are ideal for monitoring and treatment of the masticatory function in pilots.
ACTIN CYTOSKELETON ORGANIZATION IN OOCYTES AT VARIOUS STAGES OF DROSOPHILA MELANOGASTER OOGENESIS AFTER EXPOSURE IN A MICROGRAVITY SIMULATOR OVER THE COMPLETE GAMETOGENESIS CYCLE
Authors:   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Usik M.A. , Sukonkina A.A. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow, Ogneva I.V. ,   Institute of Biomedical Problems of the Russian Academy of Sciences, Moscow
Published: November 2021

The paper deals with the effects of modeled microgravity on actin cytoskeleton in oocytes at various stages of Drosophila melanogaster oogenesis over the complete gametogenesis cycle. Total actin content and F-actin singly was determined using immunohistochemical analysis. The results point to the growth of both total beta-actin and its polymer recognized by phalloidin. This finding can have key implications for evaluation of risks for the reproductive potential from the spaceflight factors.
ELECTROPHYSIOLOGICAL EVALUATION OF THE FUNCTIONAL STATE OF PERIPHERAL AUDITORY ANALYZER IN AN ACOUSTIC INJURY MODEL WITH PREVENTIVE TAKING OF AN ANTIHYPOXANT (TRIAZINOINDOLE DERIVATIVE)
Authors:   Pharm-TRISAN, St.-Petersburg, Pastushenkov V.L. , Kuznetsov М.S. ,   Kirov Military Medical Academy, St.-Petersburg, Glaznikov L.A. ,   Kirov Military Medical Academy, St.-Petersburg, Dvoryanchikov V.V. ,   Kirov Military Medical Academy, St.-Petersburg, Pastushenkov A.L. ,   Mechnikov North-Western State Medical University, St.-Petersburg, Buynov L.G. ,   Herzen State Pedagogical University of Russia, St.-Petersburg, Sorokina L.A. ,   Herzen State Pedagogical University of Russia, St.-Petersburg
Published: November 2021

The paper reports the results of testing efficiency of a triazinoindole derivative in an experiment with modeled acoustic injury. Animals (116 (CBA x C57BL/6) F1 hybrid female mice) were randomly distributed in 5 groups. Groups A, B and C received I/M triazinoindole at 5, 7 and 10 mg/kg/d respectively. Group D was injected with the cytoflavin (reference medicine) at 1.7 ml/7 мl/kg. Group E was a control that received injections of 2 ml of 0.9 % sodium chloride solution. Following 5 days of injections, the mice were exposed to white noise of 107 dB. Analysis of auditory evoked potentials demonstrated a dose-dependent oto-protective effect of the triazinoindole derivative.
EFFECT OF LIGHT INTENSITY ON CENOSIS OF WHEAT CULTIVATED ON SOLUTIONS WITH THE USE OF LIQUID PRODUCTS OF HUMAN EXOMETABOLITES MINERALIZATION IN CONTEXT OF CLOSED ECO-SYSTEMS
Authors:   Institute of Biophysics SB RAS, Federal Research Center «Krasnoyarsk Science Center SB RAS», Ushakova S.A. , Shikhov V.N. ,   Institute of Biophysics SB RAS, Federal Research Center «Krasnoyarsk Science Center SB RAS», Shklavtsova Е.S. ,   Institute of Biophysics SB RAS, Federal Research Center «Krasnoyarsk Science Center SB RAS», Trifonov S.V. ,   Institute of Biophysics SB RAS, Federal Research Center «Krasnoyarsk Science Center SB RAS», Anishchenko O.V. ,   Institute of Biophysics SB RAS, Federal Research Center «Krasnoyarsk Science Center SB RAS», Tikhomirov А.А. ,   Institute of Biophysics SB RAS, Federal Research Center «Krasnoyarsk Science Center SB RAS»
Published: November 2021

Goal of the investigation was to assess an impact of photosynthetically active radiation (RAR) intensity on crops growing hydroponically on solutions containing human exometabolites mineralized by hydrogen peroxide activated by alternating current. Object was wheat Triticum aestivum L. (strain 232, Lysovsky selection) bred for cultivation in bio-technical life support systems. Nutrient substrate was granular zirconium silencer of 0.8 cm in diameter. Till day 25 (initial booting) the crop grew under RAR intensity of 650 and 950 µmol/m2s. Well-being of the vegetating wheat was assessed by the following criteria: СО2, wheat cenosis gas-exchange, photosynthesis, nutrient uptake, plant biomass and mineral composition. High RAR intensity did not cause damage to the photosynthetic system but activated photosynthesis and increased dry biomass in 1.7 times. Besides, levels of macroelements in biomass increased significantly (Ca – more than 3 times, Mg – 2.7 times, Na – 2.3 times, S – doubled).
SUBSTANTIATION OF METHODICAL APPROACHES TO DEFINING BORDERS OF SANITARY NOISE PROTECTION ZONES IN AERODROME SURROUNDINGS
Authors:   State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Dragan S.P. , Drozdov S.V. ,   State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Soldatov S.K. ,   Central Research Institute Air Force Ministry of Defense of the Russian Federation, Moscow, Bogomolov A.V. ,   State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Shishov A.A. ,   State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Zinkin V.N. ,   Central Research Institute Air Force Ministry of Defense of the Russian Federation, Moscow, Kharitonov V.V. ,   Central Research Institute Air Force Ministry of Defense of the Russian Federation, Moscow
Published: November 2021

Borders of noise protection zones for populated aerodrome surroundings have been defined with account of equivalent and peak noise levels from different types of airplane in control points, take-off and landing paths, taxiing, day and night airline schedule, lay of land and seasonal variations. The effort was accomplished in four stages. The first stage was choosing methods and parameters to be measured. The second was analysis of airline schedule and noise produced by airplanes. The third was calculation of equivalent and peak noise levels and the fourth was setting guidelines on drawing the noise protection zones in populated airdrome surroundings.
Evaluation of aquifer recharge into Salto Chico, Hernandarias and Ubajay formations. Palmar Creek, Entre Ríos, Argentina
Authors: Silva Busso Adrián , Moreno Merino Luis , Chury Mario
Published: November 2021

The study of recharge mechanisms and volumes in aquifers is one of the most important issues for achieving sustainable exploitation of the groundwater resource. This factor has an impact on agricultural productivity as irrigation increases the yields of many crops and agriculture is the main economic activity in Argentina. However, recharge studies are not common in the country and this is why this paper is a new contribution. We have carried out a detailed study of the soil and hydrogeology in a hydrological basin. This basin is in an agricultural area typical of the Pampean region. Detailed records of precipitation, soil moisture and hydraulic head have been collected from stations designed for this purpose. We have also analyzed the influence and magnitude of vertical recharge from a water balance in the unsaturated zone. The calculation of the net recharge has also been included in the saturated zone. We have shown that the geological conditions of the basin influence the aquifer recharge. In outcrop zone of F. Ubajay the infiltration of surpluses allows a vertical transit equivalent to 6.61% with net recharge values of 1.41% of precipitation. In the outcrop zone of F. Hernandarias the conditions do not favour the infiltration of water surpluses and only allow a transit equivalent to 0.89% with a net recharge of 0.04% of precipitation. This scenario suggests that vertical recharge is not a dominant or quantitatively important process, which is atypical in Argentina’s Pampean region. These values are far from those previously established which varied between 7% and 15% of the average annual rainfall. The implications for water management in the region are significant and make it necessary to rethink the conceptual model of the aquifers in the area
MEDICAL REHABILITATION MANAGEMENT OF CARPAL TUNNEL SYNDROME
Authors: Subadi Imam , Hidayati Hanik , Fidiana Fidiana , Sulastri Nur
Published: November 2021

Carpal tunnel syndrome (CTS), the most common entrapment neuropathy in the upper extrimity, is a clinical syndrome characterized by a tingling sensation, numbness, pain, or weakness in the hand and wrist radiating up to the arm. This condition is a major cause of absenteeism, reduced productivity, and financial loss among various neuropathy due to median nerve compression. This paper, medical rehabilitation of CTS is viewed. Medical rehabilitation of CTS aimed to reduce pain, reduce clamping of the carpal tunnel, sensory and motor reeducation so that hand function improves and can perform activities of daily living. Treatment options can be given includes exercise therapy, ultrasound diathermy, low level laser therapy (LLLT), and shock wave therapy (SWT).
The Impact of Artificial Intelligence on Waiting Time for Medical Care in an Urgent Care Service for COVID-19: Single-Center Prospective Study
Authors: Bin Kaio Jia , Melo Adler Araujo Ribeiro , da Rocha José Guilherme Moraes Franco , de Almeida Renata Pivi , Cobello Junior Vilson , Maia Fernando Liebhart , de Faria Elizabeth , Pereira Antonio José , Battistella Linamara Rizzo , Ono Suzane Kioko
Published: November 2021

Background

To demonstrate the value of implementation of an artificial intelligence solution in health care service, a winning project of the Massachusetts Institute of Technology Hacking Medicine Brazil competition was implemented in an urgent care service for health care professionals at Hospital das Clínicas of the Faculdade de Medicina da Universidade de São Paulo during the COVID-19 pandemic.

Objective

The aim of this study was to determine the impact of implementation of the digital solution in the urgent care service, assessing the reduction of nonvalue-added activities and its effect on the nurses’ time required for screening and the waiting time for patients to receive medical care.

Methods

This was a single-center, comparative, prospective study designed according to the Public Health England guide “Evaluating Digital Products for Health.” A total of 38,042 visits were analyzed over 18 months to determine the impact of implementing the digital solution. Medical care registration, health screening, and waiting time for medical care were compared before and after implementation of the digital solution.

Results

The digital solution automated 92% of medical care registrations. The time for health screening increased by approximately 16% during the implementation and in the first 3 months after the implementation. The waiting time for medical care after automation with the digital solution was reduced by approximately 12 minutes compared with that required for visits without automation. The total time savings in the 12 months after implementation was estimated to be 2508 hours.

Conclusions

The digital solution was able to reduce nonvalue-added activities, without a substantial impact on health screening, and further saved waiting time for medical care in an urgent care service in Brazil during the COVID-19 pandemic.
Introduction of Systematized Nomenclature of Medicine–Clinical Terms Coding Into an Electronic Health Record and Evaluation of its Impact: Qualitative and Quantitative Study
Authors: Pankhurst Tanya , Evison Felicity , Atia Jolene , Gallier Suzy , Coleman Jamie , Ball Simon , McKee Deborah , Ryan Steven , Black Ruth
Published: November 2021

Background

This study describes the conversion within an existing electronic health record (EHR) from the International Classification of Diseases, Tenth Revision coding system to the SNOMED-CT (Systematized Nomenclature of Medicine–Clinical Terms) for the collection of patient histories and diagnoses. The setting is a large acute hospital that is designing and building its own EHR. Well-designed EHRs create opportunities for continuous data collection, which can be used in clinical decision support rules to drive patient safety. Collected data can be exchanged across health care systems to support patients in all health care settings. Data can be used for research to prevent diseases and protect future populations.

Objective

The aim of this study was to migrate a current EHR, with all relevant patient data, to the SNOMED-CT coding system to optimize clinical use and clinical decision support, facilitate data sharing across organizational boundaries for national programs, and enable remodeling of medical pathways.

Methods

The study used qualitative and quantitative data to understand the successes and gaps in the project, clinician attitudes toward the new tool, and the future use of the tool.

Results

The new coding system (tool) was well received and immediately widely used in all specialties. This resulted in increased, accurate, and clinically relevant data collection. Clinicians appreciated the increased depth and detail of the new coding, welcomed the potential for both data sharing and research, and provided extensive feedback for further development.

Conclusions

Successful implementation of the new system aligned the University Hospitals Birmingham NHS Foundation Trust with national strategy and can be used as a blueprint for similar projects in other health care settings.
Developing Graphic Messages for Vaping Prevention Among Black and Latino Adolescents: Participatory Research Approach
Authors: Cartujano-Barrera Francisco , Azogini Chiamaka , McIntosh Scott , Bansal-Travers Maansi , Ossip Deborah J , Cupertino Ana Paula
Published: November 2021

Background

As an important transition stage in human development, adolescence is a critical window for vaping prevention. There is a substantial gap in communication research on vaping prevention among racial and ethnic minority groups. Their representation is essential to develop, implement, and disseminate innovative and effective interventions for vaping prevention.

Objective

The aim of this study is to describe the participatory research (PR) procedures used with Black and Latino adolescents to develop culturally and linguistically appropriate graphic messages for vaping prevention.

Methods

This PR study used a qualitative, user-centered design method. We conducted a series of focus groups with 16 Black and Latino adolescents to develop culturally and linguistically appropriate graphic messages for vaping prevention. The biobehavioral model of nicotine addiction provided a framework for the development of the graphic messages. Participants met 4 times to provide iterative feedback on the graphic messages until they reached a consensus on overall quality and content.

Results

At baseline, the participants’ mean age was 15.4 years (SD 1.4). Of the participants, 50% (8/16) were female, 88% (14/16) were heterosexual, 56% (9/16) were Black/African American, and 44% (7/16) were Hispanic/Latino. A total of 12 of the 16 participants (75%) chose to participate in the English sessions. Participants decided to create four types of graphic messages: (1) financial reward, (2) health reward, (3) social norms, and (4) self-efficacy. Meeting 4 times with the 4 groups provided sufficient opportunities for iterative feedback on the graphic messages to reach a consensus on overall quality and content.

Conclusions

It is feasible and practical to build PR among Black and Latino adolescents focused on vaping prevention. Adolescents added innovation and creativity to the development of culturally and linguistically appropriate graphic messages for vaping prevention. Appropriate staffing, funding, and approaches are key for successful PR efforts among Black and Latino adolescents. Future research is needed to evaluate the impact of the graphic messages on vaping prevention.