bluuebunny/crossref_metadata_2025 huggingface dataset:
Dekonstruksi Peran Seme dan Uke dalam Manga Shishi mo Kobamazu
Authors: Putri Vanya Arisda , Puspitasari Diana , Widodo Heri
Published: December 2022

This research is descriptive qualitative research with the object of research manga entitled "Shishi mo Kobamazu" (2014) by Kiriyu Kiyoi. This manga is a boy's same-sex love genre that generally has a formula for the roles of Seme and Uke. The role of seme will be considered to have all the masculine traits and the role of uke to have all the feminine traits. In the Shishi mo Kobamazu manga, the roles of Seme and Uke are given a different role concept from manga boy's love in general resulting in a deconstruction of the role concepts of Seme and Uke. The aim of this research is to describe the deconstruction that occurs and its depiction in literary works so that it can be seen that the construction of gender roles in same-sex love relationships does not have a patent provision and can change according to conditions and times. The method used is a literature study. The theory used in this research is Derrida's deconstruction theory and Butler's performativity. Both theories are used to analyze the form of deconstruction in the roles of seme and uke and to understand the concept of gender roles in same-sex relationships. The results show that the character in this manga can display and form a new identity in their seme and uke roles through the performativity of gender roles in same-sex relationships. The new identity in the form of Seme and Uke is not fixed on one gender trait. Seme can be described as having a petite body and characters like women and uke can be described as having a strong and masculine physique. The roles of Seme and Uke can change according to the identity shown by each character in the manga.
Majas dan Imaji Dalam Lirik Lagu Kimi Ga Kureta Natsu Karya Reo Ieiri
Authors: Hastuti Nur , Inayah Alya Nurul
Published: December 2022

Poetry is a very famous literary work. Nowadays, song lyrics are considered a part of poetry as well. Song lyrics and similar poetry elements; such as rhymes, stanzas, etc. To make the lyrics more poetic, the lyricist can use some figures of speech and images in the lyrics. This study aims to determine the figure of speech and imagery in the song "Kimi ga Kureta Natsu" by Leo Ieiri. The method used in this research is the library method using stylistic studies as an analytical tool. The data used in this study are the lyrics of "Kimi ga Kureta Natsu" by Reo Ieiri. Based on data analysis, it can be concluded that in the lyrics of the song Kimi ga Kureta Natsu there are 3 types of figure of speech and there are 2 types of images.
Konflik Sosial Tokoh Utama dalam Film Animasi Haikyuu!! Second Season (Kajian Sosiologi Sastra)
Authors: Nurfajriyati Niken Sekar Ayu , Seruni Ayu Putri
Published: December 2022

Social conflict was defined as a natural social symptom that occurs in social life. Coser divided conflicts into several parts, there are realistic, non- realistic, in- group and out- group conflicts. He argues that social conflict not only viewed from the negative side. This research focuses on social conflicts that occur the Japanese student environment then will analyze more deeply the social conflicts experienced by the main character also will look for the factors that occurs the conflicts.  Thie aim of this studies to explains and describing (1) realistic and non- realistic conflicts that occur (2) in-group and out-group conflicts that occur (3) functions of social conflicts. This study used content analysis of qualitative research methods with literary sociology approach. For data collecting technique this study used note- taking technique. The result of this research is (1) the occurrence of realistic conflicts due to a sense of disapproval of a demand (2) the occurrence of non- realistic conflicts due to the need to relieve tensions (3) the occurrence of in-group conflicts because those involved in the conflicts are between member in the same groups (4) the occurrence of out-group conflicts because those involved in the conflicts are between different groups.
Příroda, biologie a nové technologie v umění
Authors: Kubíčková Jindra
Published: December 2022

Proud umění, v němž se setkává biologie s uměleckou tvorbou, se výrazněji objevuje především na konci dvacátého století, kdy biologie – zejména v podobě genetiky, biochemie či biotechnologií – začala otevírat nedozírné možnosti nejen pro vědce, ale i současné umělce. Biologické inspirace v umění jsou dnes označovány několika pojmy, mezi které patří bio art, transgenní umění či biologické umění a další. Přitom není vždy snadné rozeznat hranice nejen mezi jednotlivými označeními, ale i samotnými uměleckými díly. Často je ostatně obtížné určit v této tendenci hranice mezi vědou a uměním, což je také charakteristický rys práce umělců, kteří se inspirují biotechnologickými postupy. Termín bio art (někdy též Bio-Art nebo Bio Art) se zpravidla používá pro umělecká díla, jejichž hlavním tématem jsou živé organismy či pro díla vytvořená ve spolupráci s těmito organismy.
Multiplicity and minimality of periodic solutions to fourth-order super-quadratic difference systems
Authors: Ling Rumin , Lu Mingxi , Feng Yuncheng , Xiao Huafeng
Published: December 2022

In this article, we use the Nehari manifold method to study a class of fourth-order even difference systems. First, we show that there exist multiple periodic solutions to the non-autonomous system. Second, we obtain sufficient conditions to guarantee the existence of solutions with prescribed minimal periods to the autonomous system. Our results generalize the results in reference.
Validation Technique for Heavy Vehicle Simulator Rut Measurement with Florida Laser Rut Meter
Authors: Khan Shahbaz , Cotter Chris , Greene James
Published: December 2022

The performance of a pavement system is typically measured in structural and functional terms. Agencies often prioritize minimizing rutting as it indicates the mixture and structural inadequacy and can lead to safety concerns such as hydroplaning. Therefore, accurate rut depth measurement is critical to pavement management as well as to assess the performance of materials designed to resist rutting. To that measure, Florida Department of Transportation (FDOT) uses two heavy vehicle simulators (HVSs) as part of an accelerated pavement testing (APT) program to advance pavement research and implement new pavement materials, designs, and construction methods. Each HVS device is equipped with an on-board laser profiling system for rut depth measurement. To ensure accurate and reproducible rut depth measurements, a laser-based reference device was developed and constructed by FDOT to verify rut depth measurements made by both HVS devices during APT research studies. This article describes the rut depth reference device, the verification process, and data analysis methods used to validate the accuracy of the HVS devices.
Gender representation in the textbook for vocational school students in the Indonesian EFL settings
Authors: Yanti Mona Safrida , Wirza Yanty
Published: December 2022

A textbook is expected to cover all of the teaching necessities as well as educational values contained in the curriculum. Conversely, many scholars or researchers in the study of gender representation portrayed English language textbooks tend to have gender-biased in terms of gender representation in which males are represented more than females in many aspects. Hence, investigating how males and females are represented in Indonesian EFL textbooks is highly beneficial to be explored to clarify and update the finding based on the previous studies. The concern of this current study is to investigate gender representation in the Indonesian EFL textbook for vocational school students by using the framework proposed by (Amerian & Esmaili, 2014). The analysis of the data is based on critical discourse analysis and content analysis. Surprisingly, congruent with most previous studies, the finding reflects that there is inequality in terms of gender representation in which females are underrepresented in the textbook. The finding of this recent study pinpoints the depiction of how males and females are represented and depicted in the Indonesian EFL textbook, as a result, it is expected to convey the awareness of scholars, educators, textbook writers or designers, and policymakers as well related to this issue. Then, it is still highly suggested for scholars or researchers in future studies exploring gender representation in Indonesian EFL textbooks by using other books or other levels of education to evaluate the development of this issue.
Hedonism in the Young Generation: The Challenge of Pancasila Moral Education
Authors: Prajabti Annisa , Kien Xo Ho Dac , Ridho Muhammad Rasyid
Published: December 2022

Globalization can be interpreted as a global process and everything becomes more modern, easy, sophisticated, and faster without the limitations of distance, space and time. Globalization is supported by a variety of technological innovations that help human life a lot. Inevitably, globalization creates various phenomena in various aspects of life. One example is the lifestyle of hedonism among the younger generation. Hedonism itself is a view of life that is manifested in the form of a lifestyle that makes worldly pleasure the purpose of life. Many people mistakenly apply this lifestyle of hedonism, perhaps unknowingly this has become a social disease. This hedonism attacks many millennials, where millennials are the next generation of young people who should be far from the nature of hedonism. The lifestyle of hedonism itself is difficult to avoid, there needs to be an awareness of each person. Indonesia has a very strong ancestral heritage to help young people free from the hedonism lifestyle that has become a disease, namely the five principles of Pancasila. The young generation needs to inculcate the strong personality contained in Pancasila and always implement it in daily life. The values ​​and meanings of Pancasila are the guiding principles of the nation, the personality of the nation, and the ideology of the nation that is most in line with the noble soul and personality of the Indonesian Nation.
Social Capital of Pancasila Education in Smart Education with Social Media in Cybercrime Prevention in the Industrial Revolution Era 4.0
Authors: Akhuai Wen , Nugraha Aloisius Arizendy , Lukitaningtyas Yosephine Ken Rahayu Dyah , Ridho Aly , Wulansari Heni , Al Romadhona Risang Adhitya
Published: December 2022

Currently the world is undergoing major changes, namely the Industrial Revolution 4.0. The Industrial Revolution 4.0 is a change in the mechanism for the production of goods and services marked by a number of characteristics, namely the use of the internet of things, big data, automation, robotics, lay computing, to artificial intelligence. This change is not only felt by the private sector, but also by government organizations. What the community, especially students, can do to play a role in this industrial era and take steps and places as the driving force of this country is to develop a critical thinking pattern that is not easily eroded by negative influences. This means that with the amount of information that can be obtained, students must be able to see which information can be trusted and which is not and do not immediately believe in any information that is not necessarily true. In addition to the various opportunities offered in the Industrial Revolution 4.0 era, there are many new public issues that must be faced, such as online transportation polemics, the threat of e-commerce to conventional shops/retails and cybercrime. This time, we focus on cybercrime. Cybercrime is a crime that is carried out electronically. This crime takes various forms. The presence of Law Number 11 of 2008 concerning Electronic Information and Transactions has regulated the prohibited actions related to electronic information and transactions. The problem of violence that occurs through online media in fact poses a problem for the whole community. For this reason, everyone needs to get a good understanding of the impact of cybercrime, and the potential emergence of women as victims of these crimes, such as cyberstalking and cyberpornography. Through this education, it is hoped that the community will understand their rights to the maximum, especially those related to the right to obtain education and the freedom to express their opinions.
Mathematical Modelling of the Removal of Basic Blue Dye from Effluent by a Mineral Membrane
Authors: Ali Maaboodifar , Mohammad Meysami , Amirhossein Meysami , Alex Meisami
Published: December 2022

Water contamination is a major challenge due to the discharging of wastes into the natural resources. In this study, a novel branched pore adsorption model was developed by utilizing external mass transfer coefficients, Kf , effective diffusivity, and lumped microspore diffusion rate parameters. This describes sorption kinetics from long-term adsorption that occurs between an adsorbent and an adsorbate. An investigation of the effects of dye concentration on Basic Blue 9 removal was conducted. Then by considering of initial and boundary conditions the government equations were solved. Using this model, the Basic Blue 9 (or methylene blue is an industrial inhibitor) was removed from a bentonite sample polluted by Basic Blue 9. The maximum adsorption capacity was achieved by using of Freundlich analysis. Based on the experimental data, theoretical concentration - time adjusted models were developed using a FORTRAN computer program to fit the experimental data more precisely and confirm the precision and accuracy of this research.
Preparation and Characterization of Free-Standing Composite Cellulose-Based Carbon Molecular Sieve Membranes
Authors: Adelio Mendes , Tiago Arauo , Francisco Barbosa , Jose M. Sousa , Gabriel Bernardo
Published: December 2022

Carbon membranes with excellent strength and mechanical stability were prepared using a cellulose precursor regenerated from an ionic liquid solution with a low loading of boehmite ceramic nanoparticles, ca. 0.1 wt. %. The precursor films show an asymmetrical structure while, after carbonization, the corresponding carbon molecular sieve membranes (c-CMSM) show a dense structure with a uniform thickness of ca. 22 µm. The c-CMSM exhibited excellent separation performance, well above the Robeson Upper Bound. The permeability of the c-CMSM to hydrogen increased from 300 to 530 barrer and the H2/CH4 permselectivity increased to 473, after adding boehmite nanoparticles. Boehmite nanoparticles act as a microporosity-forming agent without compromising the width of the ultramicropores. The prepared c-CMSM is extremely promising for several applications, namely for hydrogen recovery from methane – H2/CH4 (Robeson index:θ=13.5); biogas upgrading – CO2/CH4 (θ=6.5); CO2 removal from combustion flue gas – CO2/N2 (θ=1.7); and hydrogen recovery from ammonia processes – H2/N2 (θ=4.8).
Impact of Synbiotic Therapy on the Quality of Life in Patients with Mild-to-Moderately Active Ulcerative Colitis
Authors: Kamarli Altun Hulya , Akal Yildiz Emine , Akin Mete
Published: December 2022

Background and Aims: Ulcerative colitis is a chronic inflammatory disease which is affecting the quality of life, workforce and nutrition of patients negatively in the active periods due to its symptoms. This study aims to explore how synbiotic treatment affects the quality of life in patients with mild-to-moderate ulcerative colitis.

Methods: Forty ulcerative colitis patients with mild-to-moderate activity were enrolled in the study. Patients were split into two even randomized groups as synbiotic (20 patients) and control (20 patients). The synbiotic group received synbiotic therapy and the control group received placebo for 8 weeks. Both groups were compared at the start and the end of therapy according to the quality of life scores. Quality of life was determined using a short form-36 (SF-36) questionnaire.

Results: An increase in mean SF-36 scores were found in both groups at the end of the study. Altough this increase was higher in patients received synbiotic therapy, the difference was not statistically significant (p > 0.05).  SF-36 scores were higher in patients with mild activity or those in remission in both groups.

Conclusion: Synbiotic use provides an increase in the SF-36 score, however, this increase is not statistically significant.
Somatostatinoma of the Ampulla of Vater: A Systematic Review
Authors: Giannakodimos Ilias , Giannakodimos Alexios , Ziogou Afroditi , Frountzas Maximos , Kritikos Neoklis , Vlachos Konstantinos , Toutouzas Konstantinos G , Schizas Dimitrios
Published: December 2022

Background and Aims: Somatostatinoma of the ampulla of Vater (SAV) is a rare neuroendocrine tumor that usually appears with atypical clinical manifestations and is associated with Von Recklinghausen’s disease. The aims of this study were to systematically review the literature regarding SAV and to highlight the clinicopathological characteristics and optimal therapeutic management of this rare entity.

Methods: A systematic search of the literature in PubMed/Medline and Scopus databases was performed by two independent investigators, including all case reports and case series concerning SAVs from 1980 until September 2021.

Results: In total, 37 articles were retrieved, including 43 patients, with a male to female ratio of 1.8:1 and a mean age of 46.8 ± 11.3 years (mean, SD). For 23 out of 43 patients (53.5%), Von Recklinghausen’s disease was proved. The main clinical manifestations were abdominal pain (41.9%), jaundice (27.9%), weight loss (20.9%) and bowel disorders (20.9%). Typical histological findings included psammoma bodies, nests or clusters of epithelial cells with eosinophilic cytoplasm, while somatostatin staining was positive in 35 patients (81.4%), chromogranin-A in 21 patients (48.8%) and synaptophysin in 18 patients (41.9%). Surgery was the initial therapeutic approach in 34 patients (79.1%), whereas Whipple’s procedure was the preferred surgical approach in 23 patients (53.4%). The longest survival among included patients was 13 years and only two postoperative deaths (4.7%) were reported.

Conclusions: Somatostatinomas of the ampulla of Vater are rare malignancies that require increased physicians’ suspicion and accurate surgical approach in order to achieve optimal therapeutic results.
Real World Efficacy and Safety of Sofosbuvir + Velpatasvir + Voxilaprevir in Romanian Patients with Genotype 1b HCV Infection Non-reponders to DAAs Therapy
Authors: Gheorghe Liana , Preda Carmen , Trifan Anca , Manuc Mircea , Stanciu Carol , Istratescu Doina , Popescu Corneliu Petru , Diculescu Mircea Mihai , Tieranu Cristian George , Manuc Teodora , Stroie Tudor Gheorghe , Iacob Speranta Maria , Iliescu Laura
Published: December 2022

Background and Aims: The sofosbuvir (SOF) / velpatasvir (VEL) / voxilaprevir (VOX) combination has been evaluated in more than 800 patients enrolled in phase II and phase III studies, where it demonstrated excellent safety and efficacy, achieving overall sustained viral response (SVR) rates of more than 95%. We aimed to assess the efficacy and safety of SOF/VEL/VOX in a real-world study, including patients previously treated for genotype 1b hepatitis C virus (HCV) infection that did not obtain a sustained viral response with previous direct‐acting antivirals (DAAs) therapy.

Methods: In Romania, through a nationwide government-funded program in 2019-2020, 213 patients with chronic hepatitis C non-responders to previous DAAs therapy, received treatment with SOF/VEL/ VOX 400/100/100 mg/day for 12 weeks. We performed a retrospective longitudinal study that included 143 individuals who were treated in Bucharest, Iași, Craiova and Constanța clinics, all with genotype 1b HCV infection. Efficacy was assessed by the percentage of patients achieving SVR 12 weeks post-treatment (SVR12). Serious adverse events (SAE) were registered.

Results: Our cohort comprised 53% males with a median age of 60 years (27÷77); 47% were pre-treated with ombitasvir/paritaprevir/ritonavir+dasabuvir ± ribavirin, 40% with ledipasvir/SOF, 13% with elbasvir/ grazoprevir. 42% of patients associated co-morbidities, 45% had compensated liver cirrhosis, 2% had treated hepatocellular carcinoma (HCC) and 1% had hepatitis B virus co-infection. SVR by intention to treat was reported in 139/143 (97.2%) and per protocol in 141/143 (98.6%). No predictive factors for SVR were identified. Rate of liver decompensation in patients with cirrhosis was 6% and was statistically associated in multivariate analysis with Child-Pugh score (p<0.01) and with severe steatosis (p=0.004). Occurrence of new HCC was reported in 3.6% of all patients with cirrhosis and was associated with poor liver function [higher Child-Pugh score (p=0.001) and low albumin levels (p=0.02)]. Serious adverse events related to therapy were reported in 1/143(0.7%).

Conclusions: SOF/VEL/VOX was highly efficient in our population of patients with a 97.2% SVR. Liver decompensation occurred in 6% of cirrhotic patients at SVR, related to hepatic dysfunction.
Sedation for Endoscopic Retrograde Cholangiopancreatography in Elderly Patients – the Effect of Intravenous Lidocaine Infusion. A Randomised, Double-Blind, Placebo Controlled Trial
Authors: Breazu Caius Mihai , Alexa Alexandru Leonard , Urs Oana , Mercea Voicu , Tantau Marcel , Bartos Adrian , Ciobanu Lidia , Ionescu Daniela
Published: December 2022

Background: Sedation of elderly patients with associated comorbidities, subjected to ERCP procedure, can produce serious complications including respiratory instability and hemodynamics caused by the administration of anesthetic substances. In this study we aimed to evaluate whether the administration of lidocaine in continuous infusion during ERCP procedure reduces the consumption of propofol and the rate of complications in these patients.

Methods: 83 patients over 65-year old, ASA II-IV score, undergoing an ERCP procedure were randomized in two groups: lidocaine group (group L) who received 1.5 mg/kg lidocaine 1% and propofol 1mg/kg at induction and then 2 mg/kg lidocaine 1% in continuous infusion during the procedure and control group (group C) who received saline in the same amount as group L and propofol 1mg/kg. The consumption of propofol, intraprocedural complications, the time of awakening and recovery, the quality of postprocedural analgesia, the satisfaction of the endoscopist were registered.

Results: Propofol consumption was statistically significantly lower in group L compared to group C [135.37 (±43.23) vs. 214.88 (±51.83), p=0.001]. The same result was obtained related to the awakening time [2.85 (±1.50) vs. 5.38 (±1.36), p=0.001] and recovery time [23.90 (±12.66) vs. 26.17 (±12.41), p<0.001], the episodes of intraprocedural desaturation (p=0.001), the involuntary intraprocedural movements (p=0.001), the endoscopist‘s satisfaction (p=0.006). No differences were found in terms of post-procedure pain scores (p=0.54).

Conclusions: Lidocaine can be administered to reduce the need for propofol, faster awakening and lower intraprocedural complications in elderly patients undergoing the ERCP procedure.
Acceptability of Hybrid Endoscopic Submucosal Dissection Using Multifunctional Snare for Small-sized Gastric Neoplasms: A Prospective Observational Study
Authors: Chiyo Taiga , Kobara Hideki , Nishiyama Noriko , Nakatani Kaho , Tada Naoya , Koduka Kazuhiro , Matsui Takanori , Kobayashi Nobuya , Fujihara Shintaro , Yachida Tatsuo , Masaki Tsutomu
Published: December 2022

Background and Aims: The most suitable procedure for resecting small-sized gastric neoplasms remains unclear. Endoscopic mucosal resection leads to non-curative resection owing to slippage of the snare, and technically difficult endoscopic submucosal dissection (ESD) is instrumentally uneconomical. A novel, cost-effective, multifunctional snare called SOUTEN is available as a hybrid ESD (h-ESD) device developed for facilitating ESD. This study aimed to assess the acceptability of h-ESD using the SOUTEN for resecting small-sized gastric neoplasms.

Methods: This was a prospective observational study conducted at our single institution between March 2019 and March 2021. Fifty-seven consecutive patients who underwent h-ESD using SOUTEN for small-sized gastric neoplasms ≤15 mm involving adenoma and tubular-type mucosal carcinoma without ulceration were enrolled. The primary outcome was curative resection rate for h-ESD. Secondary outcomes were the rates of conversion to ESD, rate of total (h-ESD + ESD) curative resection, procedure time, rates of intra-and post- operative complications, and presence of additional knives excluding hemostatic forceps.

Results: The curative resection rate of h-ESD was 89.5% (51/57). The total (h-ESD + ESD) curative resection rate was 94.7% (54/57). The mean procedure time was 21.2 (±16.5) minutes. One case of delayed bleeding occurred. Additional knives were applied in two cases.

Conclusions: The cost-efficient h-ESD using SOUTEN can be an acceptable procedure for resecting small- sized gastric neoplasms.
Automatic Diagnosis of High-Resolution Esophageal Manometry Using Artificial Intelligence
Authors: Popa Stefan Lucian , Surdea-Blaga Teodora , Dumitrascu Dan Lucian , Chiarioni Giuseppe , Savarino Edoardo , David Liliana , Ismaiel Abdulrahman , Leucuta Daniel Corneliu , Zsigmond Imre , Sebestyen Gheorghe , Hangan Anca , Czako Zoltan
Published: December 2022

Background and Aims: High-resolution esophageal manometry (HREM) is the gold standard procedure used for the diagnosis of esophageal motility disorders (EMD). Artificial intelligence (AI) might provide an efficient solution for the automatic diagnosis of EMD by improving the subjective interpretation of HREM images. The aim of our study was to develop an AI-based system, using neural networks, for the automatic diagnosis of HREM images, based on one wet swallow raw image.

Methods: In the first phase of the study, the manometry recordings of our patients were retrospectively analyzed by three experienced gastroenterologists, to verify and confirm the correct diagnosis. In the second phase of the study raw images were used to train an artificial neural network. We selected only those tracings with ten test swallows that were available for analysis, including a total of 1570 images. We had 10 diagnosis categories, as follows: normal, type I achalasia, type II achalasia, type III achalasia, esophago-gastric junction outflow obstruction, jackhammer oesophagus, absent contractility, distal esophageal spasm, ineffective esophageal motility, and fragmented peristalsis, based on Chicago classification v3.0 for EMDs.

Results: The raw images were cropped, binarized, and automatically divided in 3 parts: training, testing, validation. We used Inception V3 CNN model, pre-trained on ImageNet. We developed a custom classification layer, that allowed the CNN to classify each wet swallow image from the HREM system into one of the diagnosis categories mentioned above. Our algorithm was highly accurate, with an overall precision of more than 93%.

Conclusion: Our neural network approach using HREM images resulted in a high accuracy automatic diagnosis of EMDs.
The Risk of Postpolypectomy Bleeding in Patients Receiving Direct Oral Anticoagulants compared to Warfarin or Nonanticoagulation: A Systematic Review with Meta-Analysis
Authors: Ye Hao-zhen , Wang Ben , Zhou He , Gao Jia-jia , Li Zhi-Wei , Xu Hong-wei
Published: December 2022

Aim: The aim of our systematic review and meta-analysis was to assess the risk of postpolypectomy bleeding (PPB) in patients exposed to direct oral anticoagulants (DOACs).

Methods: A systematic search was conducted by searching the PubMed, Embase, and Cochrane Library databases using the following search terms: “(nonvitamin K antagonist oral anticoagulants or NOAC or apixaban or dabigatran or rivaroxaban or edoxaban or DOAC or direct oral anticoagulants) and polypectomy”. Studies evaluating the association between DOACs and PPB were identified.

Results: The bibliographical search yielded 103 studies. Twelve studies involving 621,279 participants were ultimately included (11 cohort studies, of which 10 were retrospective, and a randomized controlled trial.). Pooled estimates revealed a higher risk of PPB among patients using DOACs than among those without anticoagulation (odds ratio [OR]: 6.170, 95% confidence interval [CI]: 3.079 to 12.363). The same result occurred when DOACs were stopped 24 hours before polypectomy (OR: 8.66, 95% CI: 4.588 to 16.348). No significant difference was noted between overall DOACs and warfarin (OR 0.826, 95% CI 0.583 to 1.172), while for subgroups, dabigatran showed a lower PPB rate than warfarin (OR: 0.582, 95% CI: 0.340 to 0.994).

Conclusions: DOACs can significantly raise the risk of PPB, even with 24-hour withdrawal before polypectomy. In addition, a lower risk of PPB was detected for dabigatran than for warfarin.
Corneal integrity in ahmed valve implantation: pars plana vs ciliary sulcus vs anterior chamber
Authors: Sareta K Dubay , Dorian Dwarika , Ronnie Bhola
Published: December 2022

Complex and refractory glaucoma cases, non-responsive to maximal management, require surgical intervention. The Ahmed Valve, a Glaucoma Drainage Device, is widely used in these scenarios. It may be implanted into the anterior chamber, ciliary sulcus and pars plana. However, there is no general consensus in the literature on which location is best when corneal protection is considered. This paper aimed to review all these studies, including ours, to determine which may be best, while still not compromising on valve efficacy in intraocular pressure reduction.
People with disabilities family: highlighting an ancestral knowledge to guarantee food security
Authors: Madrigal Zuluaga Nina , Perez Torres Diana Carolina , Ardila Osorio Sebastián , Castrillón Builes Daniel Emilio , Mina Mina Diana Rocío
Published: December 2022

The following article describes the research carried out during 2020 in Santander de Quilichao, Cauca of the project called "Family Gardens for Santander de Quilichao" whose lines of work focused on food security and community strengthening in families with children with disabilities; through the implementation of community gardens and training for parents, addressing disability as a sample of human diversity. The project yielded positive results, having as a methodological reference the Community-Based Rehabilitation strategy; directly benefiting 45 families and 150 people, with a total of 30 urban gardens and 2 home gardens. The research carried out shows how community development can be approached holistically, taking up elements of the community; thus facilitating access to and participation of persons with disabilities.
Social security schemes in India: narrative review
Authors: Mohurle Devyani , Gurbani Neha
Published: December 2022

Social security all over the world is one of the most important and debated topic as lot so people are still considered as marginalized section of population. They are not connected to mainstream and lack basic amenities in their vicinity. Social security, measure has got more weight to its discourse since the pandemic of COVID-19 has struck. COVID-19 or coronavirus disease 2019 is the deadly viral infection caused by novel coronavirus. It was first found in Wuhan which is in Hubei province of China. Since then it has destroyed many lives and livelihood. Therefore many people are resorting to government measures as they have no option left. Apart from COVID-19 various social security schemes are necessary especially in vast country like India where the population of vulnerable section is high and cannot neglected. The schemes which are running in COVID-19 must be continued as lot of people are dependent upon them. New improved and targeted delivery of services to such section would be a welcome step to ensure the pin point transfer of benefit to the needy.
Postpartum haemorrhage: interventions and treatment of the nursing professional to prevent hypovolemic shock
Authors: Castiblanco Montañez Ruth Alexandra , Coronado Veloza Cyndi Mileni , Morales Ballesteros Laura Valentina , Polo González Tatiana Valentina , Saavedra Leyva Angie Julieth
Published: December 2022

Introduction: In Colombia, postpartum haemorrhage is the second cause of mortality in pregnant women between 24 and 34 years of age, with 6.9 cases per 1,000 live births. After childbirth, it is expected that 8.2% of Latin American women will present with postpartum haemorrhage. Objective: Screening or nursing care for women with postpartum haemorrhage to reduce the risk of hypovolemic shock, through an integrative review of the literature. Methods: Integrative review of literature following on purpose by Sasso, de Campos e Galvão; the research was carried out in Clinical Key, LILACS, CINAHL, Epistemonikos, Cochrane Library, PubMed, Scielo and Google Scholar; the articles published in the last five years, in Spanish, English and Portuguese, are classified by level of evidence and degree of recommendation. This research is low risk due to its documentary nature. Results: We collected forty and definitive articles. The information was organized in: clinical chart, nursing care and difficulties in obstetric and gynaecological care. Discussion: Nursing professionals must identify the barriers to care, assessing the resolution capacity of the institutions and analysing the cases of maternal death. The use of misoprostol with oxytocin or carbetocin alone is recommended in combination with ergometrine and oxytocin according to the volume of bleeding. Conclusion: It is pertinent to perform a physical examination to recognize signs of hemodynamic instability and hypovolemic shock, and the diagnoses and nursing interventions must focus on the provision of quality care, to avoid complications such as death.
Evaluation of the intervention “Bom Dia”, in Recife - Pernambuco-Brazil in the control of childhood obesity
Authors: Cristina Maria Silva Andrea , Brito Silva Fabiana , Lúcia Ribeiro Vasconcelos Ana , Rosana de Araújo Oliveira Sydia
Published: December 2022

Childhood obesity has been increased sharply in Brazil and worldwide, becoming a major public health problem. This study aims to evaluate the “Bom Dia” program (a multidisciplinary program to care of obese children) in Recife, Pernambuco, Brazil, according to the reach, effectiveness, adoption, implementation, and maintenance using the RE-AIM model. In this study, mixed methods were used to collect data, with triangulation of methods, documentation research, directed observation, field journal, questionnaire, and semi-structured interviews, conducted from February to December 2020. This program had a 0.95% reach at community level. Some barriers such as: inflexibility of the program schedule, poor economic conditions, access difficulties, and weak integration in Health Care Network, made in difficult to reach the target population. The program presented "adoption" by all members of the multi professional team. The intervention was successfully implemented, although some adjustments to of the logic model were required over time. “Bom Dia” has been maintained at the organizational level over the years, due to the performance of the intervention team and the support from the health organizations. Finally, despite the "reach" to the target audience had not achieved expressive results, this study is unpublished, and the intervention can promote improvements in the quality of life of obese children and adolescents. Therefore, the results of this study are important for practice and could support the implementation of similar intervention programs to control obesity in children.
Self-control and child decision-making in sociocultural context
Authors: Chaverri Chaves Pablo
Published: December 2022

Self-control is usually characterized as a skill in purely intra-individual terms, but recent scientific studies question this idea by clarifying how various contexts, both proximal and distal, can shape and contribute to explain the development of self-control, which, consequently, can be understood as a situated capacity, which is consistent with the theory of ecological rationality. The article argues on the social importance of self-control, points to neural correlates of this ability, and relates it to the idea of expected utility. After that, it refers to the influence of culture and consideration of context in the candy test and decision making. It concludes by discussing some implications of the topics reviewed for a more ecological perspective of self-control.
Alzheimer’s disease as a social problem
Authors: Navarro Mirand Nora
Published: December 2022

The purpose of the research was: to review and interpret different publications referring to Alzheimer's Disease as a social problem, especially in the family environment, it is a disease that influences the quality of life not only of those who suffer from it but also of the relatives with whom they live, the method used was the Bibliographic Documentary, reaching the conclusion that it is a degenerative disease of neurological order that affects the quality of life of the patient and the relatives if it is not addressed promptly in order to control its effects, it interferes negatively in the life of the patient and the family environment, in many opportunities for its detection and treatment influences the economic aspect, since if the necessary monetary resources are not available, the patient does not receive treatment and the disease worsens.
Population aging. an approach from community health
Authors: Nemerovsky Julio
Published: December 2022

The aging of the individual as a result of medical advances and the aging of the population as a result of the compression of morbidity and the expansion of life expectancy, in the context of a lower birth rate, both in developed and developing countries, they determine a new spectrum of need for interventions, in which community commitment plays a preponderant role. The recognition of the heterogeneity of the aging process and the detection of frailty in the age group of the Elderly requires action derived from the community as a whole, as a collective expression of health. This expression determines not only the prevention of disease, disability and dependency, but also a true promotion of health aimed at achieving the desired healthy aging.
Reincorporation of victims of enforced disappearance in their workplace
Authors: Rivera Cornejo Rosa Aida , Pardes Berumen Luis Enrique , Munoz Briones Rosa Maria , Salcedo Triana Oralia , Del Hoyo Soto Salvador , Cortes Rivera Jorge Eduardo , Cortes Rivera Omar Alejandro
Published: December 2022

The statistical increase in the commission of crimes such as Forced Disappearance in Mexico has generated a great social impact and despite the years, regulations and established strategies, it continues to grow constantly, affecting individuals individually, as well as in the scenarios in which unfolds on a daily basis. Approximately only 55% of people who have been victims of this crime are located alive and most of them are of working age, for which it is necessary in companies and institutions to train and develop protocols for human resources departments, seeking to be able to get involved in the prevention, care and intervention of the same, due to the bio-psycho-social sequelae that may affect the employee and consequently decrease productivity and quality within the company.
Colombian water sources polluted by car-washgenerated sludge
Authors: Parra-Aparicio Gina , Patiño-Martínez Pedro , Daza-Orsini Sandra
Published: December 2022

The fact that Colombian hydric sources, despite their great importance, can contain microorganisms, led this study to categorize sludge from car wash, because this activity results in high volume of residual water that fluctuates, according to wash demand, between 0.5 and 1.0lt/sec. Detergents, fats, oil, fuels and sediment, among many others, produce very high pollution levels. A three-period experimental design carried out taking random samples of sludge found presence of Salmonella, somatic phages, helminth eggs and fecal coliforms coming from three car wash locations around metropolitan Bucaramanga, Colombia. Sludge analyzed was classified as category B, apt for different uses in forest plantations, as precursor material in production of construction materials, and energy-valorization processes.
A study of antimicrobial and antioxidant activity to ethanolic extract of sider (Ziziphus spina-christi) leafs against some Pathogenic microorganisms
Authors: Al-Husami Rasheed , B Abdullah Abdulmageed , Al-zaemey Abdulbaki
Published: December 2022

The antimicrobial activity of ethanolic extracts of Ziziphus spina- christi leafs were examined by using agar well diffusion method against five bacteria (Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus cereus, Escherichia coli and Staphylococcus epidermides) in addition to Candida albicans. Results of this present study indicated that the ethanol extract of Ziziphus spina- christi leafs was effective against tested gram positive and negative bacteria whereas the C. albicans was showed resistance to this extract. Results showed that the gram positive bacteria more sensitivity to ethanolic extract of Ziziphus spina- christi leafs at all concentration used (from 5% to 30%) than gram negative bacteria. The highest inhibition zone was by a high concentration of Ziziphus spina-christi ethanolic extract 30% against S. aureus with inhibition zone equal (19mm) while, the lower inhibition zone given by second concentration 20% against P. aeruginosa with inhibition zone equal to (9mm). The results of the 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging activity of ethanolic extract possess high antioxidant activity at different concentrations with IC50 value equal to 176µg ml compared to the IC50 value of control sample (L-Ascorbic acid) equal to 145.88µg/ml.
Fundamental knowledge for nurses
Authors: Lu Da-Yong , Chen Yu-Zheng , Lu Da-Feng
Published: December 2022

To great promotion for nursery practice is indispensable. Knowledge for different patterns of healthcare services and nursery should be widen and more helpful. The different backgrounds and personal condition of nurses may be optimized in the clinic. This editorial addresses many interesting topic about nursery disciplines in the clinic.
COVID impact on pattern of ischemic heart disease in comparable period
Authors: Bhanupriya Bhanupriya , Chugh Deepa
Published: December 2022

Aim: To compare the impact of COVID-19 on pattern of Ischemic Heart Disease in comparable period by assessing the incidence, severity of symptoms and in-hospital mortality of Ischemic Heart Disease patients before and during COVID-19. Background: COVID-19 directly or indirectly, affects the cardiovascular system it not only causes myocardial injury but also reduces the incidence and increasing the severity and mortality of Ischemic Heart Disease patients and it was seen that pneumonia and influenza infections increases the risk of acute MI by six folds. Methods: Data collected from health records of patients admitted in National Heart Institute from Ischemic Heart Disease in comparable four months period of before (Oct 2019-Jan 2020) and during (Oct 2020-Jan 2021)COVID-19 by using a self-structured bio physiological tool. The total samples taken were 421 out of which 237 were before COVID-19 and 184 were during COVID-19. STARD checklist used to report the study. Results: The major findings of the study reveals that incidence of ischemic heart disease indicates that before COVID-19 incidence was 13.32% whereas the incidence of ischemic heart disease during COVID-19 was 12.69%. This means incidence decreases during COVID-19 as compared to before COVID-19. Severity scores measured before COVID-19 showed the majority of the patient (61.2%) having no severity as compared to during COVID-19 whereas the majority of patients having mild (41.8%) and moderate (1.1%) severity as compared to before COVID-19. Mortality of ischemic heart disease indicates that before COVID-19 in-hospital mortality was 1.28% whereas in-hospital mortality of ischemic heart disease during COVID-19 was 0.54%. Conclusion: From findings the study interprets that incidence and in-hospital mortality of Ischemic Heart Disease patients decreases during COVID-19 as compared to before COVID-19, whereas the severity of Ischemic Heart Disease symptoms increases during COVID-19 as compared to before COVID-19. Implication: Patients are staying away from the hospital due to fear of contracting the infection which in return act as a major issue of increasing Ischemic Heart Disease severity so, the nurses should involve in a proactive campaign to alleviate patient concern and encourage them to seek timely medical attention despite the COVID-19 pandemic.
Oeuvre of Grigory Skovoroda in polish scientific thought
Authors: Pilipowicz Denys
Published: December 2022

The article is devoted to present Polish research on the literary work and philosophical thought of Hryhorii Skovoroda. The scientific reflection on Skovoroda’s legacy was initially carried out on the historical and literary level. It was initiated by Adam Honory Kirkor in 1874. In the context of the history of Ukrainian literature, Józef Tretiak, Ivan Franko and Bohdan Lepkyi presented the general characteristics of Skovoroda’s work, seeing in it only the original style and compilation character of thoughts. Ivan Mirtchuk started his research on Skovoroda’s thoughts from the history of national philosophy, seeing in Skovoroda’s philosophy the features charac- teristic of Ukrainian philosophy, differing it fundamentally from Russian philosophy. As part of the research, it was possible to find an extensive article by Jarosław Ulwański, Philosophy of G.S. Skovoroda, published in 1930, in which the author presented arguments for a pantheistic interpretation of the Ukrainian philosopher’s thoughts. A breakthrough event was the publication of a monograph by Dmytro Tschižewskij, who formulated a view on the mystical philosophy of Skovoroda similar to the Western European mysticism of the 17th and 18th centuries. The interwar period ends with the work of Czesław Jastrzębiec-Kozłowski, in which the work of Skovoroda was analyzed against the background of Józef Hoene-Wronski’s messianic philosophy. After World War II and the 1990s, research on Skovoroda’s legacy was conducted primarily by philologists. Ryszard Łużny and Włodzimierz Mokry treated Skovoroda’s work as a Christian philosopher. In the 21st century, Polish research increasingly refers to philosophical interpretation. Denys Pilipowicz researched the ancient and patristic sources of Skovoroda’s mystical thought and compared it with the teachings of Paisij Velyczkovskyi. Iryna Betko analyzed his poetry from the perspective of Jung’s theory of archetypes. Michał Handzel conducted an in-depth historical and philosophical analysis of Skovoroda’s philosophy, seeing Skovoroda as a representative of the panentheistic trend, and Pavlo Snopkov examined the concept of Skovoroda’s self-knowledge from the perspective of Jung’s and Maslow’s psychological theories.