bluuebunny/crossref_metadata_2025 huggingface dataset:
Successful treatment of hemochromatosis with renal tubular dysgenesis in a preterm infant
Authors: Koura Uta , Horikawa Shinjiro , Okabe Mako , Kawasaki Yukako , Makimoto Masami , Mizuta Koichi , Yoshida Taketoshi
Published: June 2015

Key Clinical Message

We report the first surviving case of neonatal hemochromatosis with renal tubular dysgenesis. Renal failure was treated with peritoneal dialysis. Although hepatic failure from neonatal hemochromatosis was progressive, repeated exchange transfusions improved jaundice and coagulopathy. The patient gained weight and received a liver transplantation from her father.
A giant abdominal hematoma caused by seatbelt injury led to the development of shock
Authors: Nishino Tomoya , Morita Seiji , Sakurai Keiji , Watanabe Yasue
Published: June 2015

Key Clinical Message

Trauma to soft tissues is an important consideration in cases of seatbelt injury, as soft‐tissue injury can cause shock. Careful observation for hours in the clinic at least, along with appropriate imaging studies, is necessary if signs of a seatbelt injury exist.
Sulfur‐Doped Carbon Aerogel as a Metal‐Free Oxygen Reduction Catalyst
Authors: Seredych Mykola , László Krisztina , Bandosz Teresa J.
Published: June 2015

Resorcinol‐formaldehyde‐based carbon aerogels were modified by treatment with H2S at 650 and 800 °C and used as catalysts for the oxygen reduction reaction (ORR) in an alkaline medium. On the material treated at high temperature, the electron transfer number was close to 4 e− and the onset potential for the ORR was shifted to a more positive value. An excellent tolerance to methanol crossover was also detected. The treatment resulted in sulfur doping in the form of thermally stable thiophenic compounds, which increased the surface hydrophobicity. This sulfur leads to a positive charge on the carbon atoms, which are the reaction sites. The hydrophobicity of the surface enhances the withdrawal of O2 from the electrolyte and its adsorption on the surface. The specific micro‐/mesoporosity contributes to a high dispersion of sulfur heteroatoms on the surface and to the accessibility of the surface sites to the electrolyte and thus to oxygen dissolved in water.
Enhanced Chemical Reactivity of Pristine Graphene Interacting Strongly with a Substrate: Chemisorbed Carbon Monoxide on Graphene/Nickel(1 1 1)
Authors: Smerieri Marco , Celasco Edvige , Carraro Giovanni , Lusuan Angelique , Pal Jagriti , Bracco Gianangelo , Rocca Mario , Savio Letizia , Vattuone Luca
Published: June 2015

Graphene is usually considered a chemically inert material. Theoretical studies of CO adsorption on free‐standing graphene predict quite low adsorption energies (<0.1 eV). However, we show here by vibrational spectroscopy and scanning tunneling microscopy that the nondissociative chemisorption of CO occurs at cold, pristine graphene grown on Ni(1 1 1). The CO adlayer remains stable up to 125 K, although some coverage survives flashes to 225 K. This unexpected result is explained qualitatively by the modification of the density of states close to the Fermi energy induced by the relatively strong graphene–substrate interaction. The value of the adsorption energy allows us to estimate an equilibrium coverage of the order of 0.1 monolayers at 10 mbar pressure, which thus paves the way for the use of graphene as a catalytically active support under realistic conditions.
MOR/SBA‐15 Composite Catalysts with Interconnected Meso/Micropores for Improved Activity and Stability in Isopropylation of Naphthalene
Authors: Banu Marimuthu , Lee Young Hye , Magesh Ganesan , Nam Chang‐Mo , Lee Jae Sung
Published: June 2015

The isopropylation of naphthalene with isopropyl alcohol was studied over composites of MOR/SBA‐15 in a high‐pressure, fixed‐bed reactor. The MOR catalyst showed a high 2,6‐/2,7‐diisopropyl naphthalene (DIPN) ratio of 1.75, but a low naphthalene conversion (54 %) and fast deactivation of the catalyst. The composites of MOR/SBA‐15 were prepared by a hydrothermal recrystallization process to obtain hierarchical micro/mesopores. During the process, MOR recrystallized in the mesopores of SBA‐15, the structure of which was stabilized by carbon coating formed on the pore walls as a template. The best prepared MOR/SBA‐15 catalyst achieved a high conversion of 85 %, high stability, and less coking, while maintaining the high 2,6‐/2,7‐DIPN ratio (≈1.8). The modified micro/mesopore structure allowed facile diffusion of bulky molecules to and from active catalytic sites located in the small MOR pores as a result of the connection between the two types of pores in the MOR/SBA‐15 composite.
Influence of Different Palladium Precursors on the Properties of Solution‐Combustion‐Synthesized Palladium/Ceria Catalysts for Methane Combustion
Authors: Colussi Sara , Gayen Arup , Boaro Marta , Llorca Jordi , Trovarelli Alessandro
Published: June 2015

A series of Pd/CeO2 catalysts was prepared by solution combustion synthesis (SCS) using different Pd precursors. The powders were characterized by complementary techniques such as BET surface area measurements, X‐Ray diffraction analysis, X‐Ray photoelectron spectroscopy, temperature‐programmed reduction, temperature‐programmed oxidation, and high‐resolution TEM. The results obtained evidenced the formation of a Pd‐Ce solid solution on all SCS samples. This solid solution is in the form of an ordered supercell structure only in the SCS catalyst prepared from palladium nitrate. This was correlated to the heat of reaction between Pd(NO3)2 and the fuel. The samples were tested for methane catalytic combustion, and the reaction rates on all SCS samples were approximately twice that of the impregnated counterpart, irrespective of the precursor. This was attributed to the presence of the Pd‐O‐Ce solid solution, which gave rise to strong Pd–ceria interactions.
Performance Evaluation of Two High‐Shear Impellers in an Unbaffled Stirred Tank
Authors: Ramírez‐Gómez Ruben , García‐Cortés Daniel , Martínez‐de Jesús Gaston , González‐Brambila Margarita M. , Alonso Alejandro , Martínez‐Delgadillo Sergio A. , Ramírez‐Muñoz Jorge
Published: June 2015

High‐shear impellers (HSIs) are mixers used in industrial stirred tanks to incorporate powders into liquids and break down particle agglomerates. A detailed numerical study of two commercial ring‐style HSIs of laboratory scale was carried out and their performance was compared with the Rushton turbine (RT). It was found that power and pumping numbers or their ratio cannot be simply connected for properly selecting an impeller in applications where highly localized viscous dissipation is desirable. The ratio of the average viscous dissipation in the impeller swept volume to the mean in the entire volume at two constant values of power input turned out to be lower for HSIs compared to that evaluated for RT. However, at higher power input, the dimensionless average viscous dissipation in the blade swept volume was found to be similar for the HSI of two rings and the RT, corroborating the high local viscous dissipation of this HSI when operated at higher speeds.
Effects of Surfactants on Mass Transfer from Single Carbon Dioxide Bubbles in Vertical Pipes
Authors: Aoki Jiro , Hayashi Kosuke , Hosokawa Shigeo , Tomiyama Akio
Published: June 2015

Mass transfer from single fully contaminated carbon dioxide bubbles rising through vertical pipes was measured to investigate the effects of surfactants. The diameter ratio of the bubble diameter to the pipe diameter was varied to cover various bubble shapes from ellipsoidal to Taylor bubbles. Triton X‐100 and 1‐octanol served as surfactants. The mass transfer rates, kL, of contaminated bubbles in the ellipsoidal regime were smaller than those of clean bubbles due to the interface immobilization. The kL of Taylor bubbles contaminated with Triton X‐100 and 1‐octanol showed varying trends because of the difference in the surfactant distributions at the bubble interfaces which strongly depend on the Hatta number. The Sherwood numbers of contaminated bubbles were well correlated by introducing the bubble diameter, at which the bubble shape transits from ellipsoidal to Taylor bubbles.
Power Draw and Gas‐Liquid Mass Transfer Characteristics of a Stirred‐Tank Reactor with Draft Tube Configuration
Authors: Lueske Juergen , Kar Kishore , Piras Luciano , Pressler Jim
Published: June 2015

Stirred‐tank reactors (STR), in which gas and liquid phases make intimate contact for mass transfer, are quite common in chemical processes. Mechanical agitation enhances the mixing performance and the oxygen transfer capability in bio‐STR, but they cannot be aerated at high rates because of impeller flooding. Another type of reactor widely used in bioprocessing is the airlift bioreactor, which consists of a draft tube and operates with an internal airlift loop. In this work, the mass transfer characteristics of a draft tube‐impeller agitation system (combination of a conventional airlift and a stirred bioreactor) were investigated in a large‐scale tank. The draft tube design configuration shows superior mass transfer performance compared to a conventional down‐pumping agitation system consisting of a Rushton turbine combined with a pitched‐blade turbine.
Determination of Particle Size Distributions in Multiphase Systems Containing Nonspherical Fluid Particles
Authors: Panckow Robert P. , Comandè Giorgio , Maaß Sebastian , Kraume Matthias
Published: June 2015

The presented results are obtained by means of an automated image analysis software capable of measuring particle diameters in photographs taken in situ by a 2D photo‐optical measurement device. Initially, the applicability of this measurement method must be proven for fluid particle systems on the basis of spherical‐shaped particles. As a first approach in targeting the issue of irregularly shaped fluid particles, a pure gas‐liquid system is analyzed to investigate the influence of the variation of operating parameters. In the second step, the spherical shape is changed by reducing the surface‐active auxiliaries. The usage of shape factors helps to interpret the appearance of the 2D projected objects. By examining the capabilities and limitations, it is demonstrated that the size of fluid particles can be detected online and in situ in order to analyze and control the particular chemical process.
An Alternative Approach to PEPPSI Catalysts: From Palladium Isonitriles to Highly Active Unsymmetrically Substituted PEPPSI Catalysts
Authors: Zeiler Anna , Rudolph Matthias , Rominger Frank , Hashmi A. Stephen K.
Published: June 2015

A series of new pyridine‐enhanced precatalyst preparation, stabilization, and initiation (PEPPSI)‐type complexes bearing different types of carbene ligands was prepared by the modular and convergent template synthesis strategy. Nitrogen acyclic carbenes, saturated and unsaturated five‐membered NHC, saturated six‐membered NHCs, and five‐membered N‐heterocyclic oxo‐carbene (NHOC) ligands on palladium were prepared this way. These new organometallic compounds then were tested in Suzuki and Negishi cross‐coupling reactions by using substrates with one or two substituents in ortho‐position of the new CC bond being formed. Both aryl chlorides and bromides were tested as coupling partners. In some cases, the new ligands gave results similar to Organ’s successful IPr‐based and IPent‐based PEPPSI derivatives, with aryl bromides 0.05 mol % catalyst load still gave satisfactory results, with aryl chlorides 0.5 mol % were needed.
Bis[(dialkylamino)cyclopropenimine]‐Stabilized PIII‐ and PV‐Centered Dications
Authors: Kozma Ágnes , Rust Jörg , Alcarazo Manuel
Published: June 2015

The treatment of bis[(dialkylamino)cyclopropenimines] with dihalophosphines in the presence of trimethylsilyl trifluoromethanesulfonate (TMSOTf) to form diimine‐stabilized PIII‐centered dications is reported. The structures of the new compounds were determined by using X‐ray diffraction analysis and their donor abilities as ligands evaluated through electrochemical methods. Despite the two positive charges that they bear, these compounds depict intermediate behavior between that of phosphines and phosphites. The coordination of the [L2PR]2+ moiety to AuI and AgI is also reported. Even more surprisingly, these phosphorus centers can be oxidized to the corresponding PV dications in the presence of strong oxidants such as peroxides or XeF2.
Coronenetetraimide‐Centered Cruciform Pentamers Containing Multiporphyrin Units: Synthesis and Sequential Photoinduced Energy‐ and Electron‐Transfer Dynamics
Authors: Hasobe Taku , Ida Koichi , Sakai Hayato , Ohkubo Kei , Fukuzumi Shunichi
Published: June 2015

A series of coronenetetraimide (CorTIm)‐centered cruciform pentamers containing multiporphyrin units, in which four porphyrin units are covalently linked to a CorTIm core through benzyl linkages, were designed and synthesized to investigate their structural, spectroscopic, and electrochemical properties as well as photoinduced electron‐ and energy‐transfer dynamics. These systems afforded the first synthetic case of coroneneimide derivatives covalently linked with dye molecules. The steady‐state absorption and electrochemical results indicate that a CorTIm and four porphyrin units were successfully characterized by the corresponding reference monomers. In contrast, the steady‐state fluorescence measurements demonstrated that strong fluorescence quenching relative to the corresponding monomer units was observed in these pentamers. Nanosecond laser flash photolysis measurements revealed the occurrence of intermolecular electron transfer from triplet excited state of zinc porphyrins to CorTIm. Femtosecond laser‐induced transient absorption measurements for excitation of the CorTIm unit clearly demonstrate the sequential photoinduced energy and electron transfer between CorTIm and porphyrins, that is, occurrence of the initial energy transfer from CorTIm (energy donor) to porphyrins (energy acceptor) and subsequent electron transfer from porphyrins (electron donor) to CorTIm (electron acceptor) in these pentamers, whereas only the electron‐transfer process from porphyrins to CorTIm was observed when we mainly excite porphyrin units. Finally, construction of high‐order supramolecular patterning of these pentamers was performed by utilizing self‐assembly and physical dewetting during the evaporation of solvent.
Enhanced Photocatalytic Activity of MIL‐125 by Post‐Synthetic Modification with CrIII and Ag Nanoparticles
Authors: Abdelhameed Reda M. , Simões Mário M. Q. , Silva Artur M. S. , Rocha João
Published: June 2015

NH2‐MIL‐125, [Ti8O8(OH)4(bdc‐NH2)6] (bdc2−=1,4‐benzene dicarboxylate) is a highly porous metal–organic framework (MOF) that has a band gap lying within the ultraviolet region at about 2.6 eV. The band gap may be reduced by a suitable post‐synthetic modification of the nanochannels using conventional organic chemistry methods. Here, it is shown that the photocatalytic activity of NH2‐MIL‐125 in the degradation of methylene blue under visible light is remarkably augmented by post‐synthetic modification with acetylacetone followed by CrIII complexation. The latter metal ion extends the absorption from the ultraviolet to the visible light region (band gap 2.21 eV). The photogenerated holes migrate from the MOF’s valence band to the CrIII valence band, promoting the separation of holes and electrons and increasing the recombination time. Moreover, it is shown that the MOF’s photocatalytic activity is also much improved by doping with Ag nanoparticles, formed in situ by the reduction of Ag+ with the acetylacetonate pendant groups (the resulting MOF band gap is 2.09 eV). Presumably, the Ag nanoparticles are able to accept the MOF’s photogenerated electrons, thus avoiding electron–hole recombination. Both, the Cr‐ and Ag‐bearing materials are stable under photocatalytic conditions. These findings open new avenues for improving the photocatalytic activity of MOFs.
Fluorescent Dendritic Organogels Based on 2‐(2′‐Hydroxyphenyl)benzoxazole: Emission Enhancement and Multiple Stimuli‐Responsive Properties
Authors: Chen Hui , Feng Yu , Deng Guo‐Jun , Liu Zhi‐Xiong , He Yan‐Mei , Fan Qing‐Hua
Published: June 2015

A new highly efficient and versatile poly(benzyl ether) dendritic organogelator HPB‐G1 with 2‐(2′‐hydroxyphenyl)benzoxazole (HPB) at the focal point has been designed and synthesized. HPB‐G1 can form stable organogels toward various apolar and polar organic solvents. Further studies revealed that intermolecular multiple π–π stacking interactions are the main driving forces for the formation of the organogels. Notably, dendron HPB‐G1 exhibited a significantly enhanced emission in the gel state in contrast to weak emission in solution. Most interestingly, these dendritic organogels exhibited multiple stimuli‐responsive behaviors upon exposure to environmental stimuli, including temperature, sonication, shear stress, and the presence of anions, metal cations, acids/bases, thus leading to reversible sol–gel phase transitions.
Driving Helical Packing of a Cyanine Dye on Dendron Nanofiber: Gel‐Shrinkage‐Triggered Chiral H‐Aggregation and Enhanced Enantiodiscrimination
Authors: Qin Long , Xie Fan , Jin Xue , Liu Minghua
Published: June 2015

An intelligent molecular hydrogel with a volume phase transition was constructed to regulate the chiral packing of a well‐known cyanine dye on a dynamically self‐assembled chiral nanofiber by using a pH trigger. During the shrinkage of the gel, the chiral nanofiber hierarchically assembled into a superhelix and simultaneously drove the dye molecules to stack, from a predominantly monomer form, in an unexpected helical H‐aggregation manner. Through such a transformation, the supramolecular chirality of the system was significantly enhanced and a new property of visual discrimination for chiral amines emerged.
Ultraviolet Photolysis Studies on XeO4 in Noble‐Gas and F2 Matrices and the Formation and Characterization of a New XeVIII Oxide, (η2‐O2)XeO3
Authors: Vent‐Schmidt Thomas , Goettel James T. , Schrobilgen Gary J. , Riedel Sebastian
Published: June 2015

The photolytic behavior of the thermochemically unstable xenon(VIII) oxide XeO4 was investigated by UV irradiation in noble‐gas and F2 matrices. Photolysis of Xe16O4 or Xe18O4 in noble‐gas matrices at 365 nm yielded XeO3 and a new xenon(VIII) oxide, namely, (η2‐O2)XeO3, which, along with XeO4, was characterized by matrix‐isolation IR spectroscopy and quantum‐chemical calculations. Calculations of the UV spectrum showed that the photodecomposition is induced by an n→σ* transition, but the nature of the excitation differs when different light sources are used. There is strong evidence for the formation of mobile 1D excited O atoms in the case of excitation at 365 nm, which led to the formation of (η2‐O2)XeO3 by reaction with XeO4. Matrix‐isolation IR spectroscopy in Ne and Ar matrices afforded the natural‐abundance xenon isotopic pattern for the ν3(T2) stretching mode of Xe16O4, and 18O enrichment provided the 16O/18O isotopic shifts of XeO4 and (η2‐O2)XeO3.
Monodisperse AgSbS2 Nanocrystals: Size‐Control Strategy, Large‐Scale Synthesis, and Photoelectrochemistry
Authors: Zhou Bin , Li Mingrun , Wu Yihui , Yang Chi , Zhang Wen‐Hua , Li Can
Published: June 2015

We report an efficient approach to the synthesis of AgSbS2 nanocrystals (NCs) by colloidal chemistry. The size of the AgSbS2 NCs can be tuned from 5.3 to 58.3 nm with narrow size distributions by selection of appropriate precursors and fine control of the experimental conditions. Over 15 g of high‐quality AgSbS2 NCs can be obtained from one single reaction, indicative of the up‐scalability of the present synthesis. The resulting NCs display strong absorptions in the visible‐to‐NIR range and exceptional air stability. The photoelectrochemical measurements indicate that, although the pristine AgSbS2 NC electrodes generate a cathodic photocurrent with a relatively small photocurrent density and poor stability, both of them can be significantly improved subject to CdS surface modification, showing promise in solar energy conversion applications.
Bioorthogonal Labeling, Bioimaging, and Photocytotoxicity Studies of Phosphorescent Ruthenium(II) Polypyridine Dibenzocyclooctyne Complexes
Authors: Tang Tommy Siu‐Ming , Yip Alex Man‐Hei , Zhang Kenneth Yin , Liu Hua‐Wei , Wu Po Lam , Li King Fai , Cheah Kok Wai , Lo Kenneth Kam‐Wing
Published: June 2015

The synthesis, characterization, photophysics, lipophilicity, and cellular properties of new phosphorescent ruthenium(II) polypyridine complexes functionalized with a dibenzocyclooctyne (DIBO) or amine moiety [Ru(N^N)2(L)](PF6)2 are reported (L=4‐(13‐N‐(3,4:7,8‐dibenzocyclooctyne‐5‐oxycarbonyl) amino‐4,7,10‐trioxa‐tridecanyl‐aminocarbonyl‐oxy‐methyl)‐4′‐methyl‐2,2′‐bipyridine bpy‐DIBO, N^N=2,2′‐bipyridine bpy (1 a), 1,10‐phenanthroline phen (2 a); L=4‐(13‐amino‐4,7,10‐trioxa‐tridecanylaminocarbonyl‐oxy‐methyl)‐4′‐methyl‐2,2′‐bipyridine bpy‐NH2, N^N=bpy (1 b), phen (2 b)). The strain‐promoted alkyne–azide cycloaddition (SPAAC) reaction of the DIBO complexes 1 a and 2 a with benzyl azide were studied. Also, the DIBO complexes 1 a and 2 a can selectively label N‐azidoglycans located on the surface of CHO‐K1 and A549 cells that were pretreated with 1,3,4,6‐tetra‐O‐acetyl‐N‐azidoacetyl‐D‐mannosamine (Ac4ManNAz). Additionally, the intracellular trafficking and localization of these biomolecules were monitored using laser‐scanning confocal microscopy. Interestingly, the biolabeling and cellular uptake efficiency of the DIBO complexes 1 a and 2 a were cell‐line dependent, as revealed by flow cytometry and ICP‐MS. Furthermore, the complexes showed good biocompatibility toward the Ac4ManNAz‐pretreated cells in the dark, but exhibited photoinduced cytotoxicity due to the generation of singlet oxygen.
Generation of Molecular Complexity from Cyclooctatetraene: Preparation of Aminobicyclo[5.1.0]octitols
Authors: El‐Mansy Mohamed F. , Flister Matthew , Lindeman Sergey , Kalous Kelsey , Sem Daniel S. , Donaldson William A.
Published: June 2015

A series of eight stereoisomeric N‐(tetrahydroxy bicyclo‐[5.1.0]oct‐2S*‐yl)phthalimides were prepared in one to four steps from N‐(bicyclo[5.1.0]octa‐3,5‐dien‐2‐yl)phthalimide (±)‐7, which is readily available from cyclooctatetraene (62 % yield). The structural assignments of the stereoisomers were established by 1H NMR spectral data as well as X‐ray crystal structures for certain members. The outcomes of several epoxydiol hydrolyses, particularly ring contraction and enlargement, are of note. The isomeric phthalimides as well as the free amines did not exhibit β‐glucosidase inhibitory activity at a concentration of less than 100 μM.
Direct On‐Surface Patterning of a Crystalline Laminar Covalent Organic Framework Synthesized at Room Temperature
Authors: de la Peña Ruigómez Alejandro , Rodríguez‐San‐Miguel David , Stylianou Kyriakos C. , Cavallini Massimiliano , Gentili Denis , Liscio Fabiola , Milita Silvia , Roscioni Otello Maria , Ruiz‐González Maria Luisa , Carbonell Carlos , Maspoch Daniel , Mas‐Ballesté Rubén , Segura José Luis , Zamora Félix
Published: June 2015

We report herein an efficient, fast, and simple synthesis of an imine‐based covalent organic framework (COF) at room temperature (hereafter, RT‐COF‐1). RT‐COF‐1 shows a layered hexagonal structure exhibiting channels, is robust, and is porous to N2 and CO2. The room‐temperature synthesis has enabled us to fabricate and position low‐cost micro‐ and submicropatterns of RT‐COF‐1 on several surfaces, including solid SiO2 substrates and flexible acetate paper, by using lithographically controlled wetting and conventional ink‐jet printing.
Facile Fabrication of Graphene‐Containing Foam as a High‐Performance Anode for Microbial Fuel Cells
Authors: Yang Lu , Wang Shuqin , Peng Shuqin , Jiang Hongmei , Zhang Youming , Deng Wenfang , Tan Yueming , Ma Ming , Xie Qingji
Published: June 2015

Facile fabrication of novel three‐dimensional anode materials to increase the bacterial loading capacity and improve substrate transport in microbial fuel cells (MFCs) is of great interest and importance. Herein, a novel graphene‐containing foam (GCF) was fabricated easily by freeze‐drying and pyrolysis of a graphene oxide–agarose gel. Owing to the involvement of graphene and stainless‐steel mesh in the GCF, the GCF shows high electrical conductivity, enabling the GCF to be a conductive electrode for MFC applications. With the aid of agarose, the GCF electrode possesses a supermacroporous structure with pore sizes ranging from 100–200 μm and a high surface area, which greatly increase the bacterial loading capacity. Cell viability measurements indicate that the GCF possesses excellent biocompatibility. The MFC, equipped with a 0.4 mm‐thick GCF anode, shows a maximum area power density of 786 mW m−2, which is 4.1 times that of a MFC equipped with a commercial carbon cloth anode. The simple fabrication route in combination with the outstanding electrochemical performance of the GCF indicates a promising anode for MFC applications.
Rapid Vortex Fluidics: Continuous Flow Synthesis of Amides and Local Anesthetic Lidocaine
Authors: Britton Joshua , Chalker Justin M. , Raston Colin L.
Published: June 2015

Thin film flow chemistry using a vortex fluidic device (VFD) is effective in the scalable acylation of amines under shear, with the yields of the amides dramatically enhanced relative to traditional batch techniques. The optimized monophasic flow conditions are effective in ≤80 seconds at room temperature, enabling access to structurally diverse amides, functionalized amino acids and substituted ureas on multigram scales. Amide synthesis under flow was also extended to a total synthesis of local anesthetic lidocaine, with sequential reactions carried out in two serially linked VFD units. The synthesis could also be executed in a single VFD, in which the tandem reactions involve reagent delivery at different positions along the rapidly rotating tube with in situ solvent replacement, as a molecular assembly line process. This further highlights the versatility of the VFD in organic synthesis, as does the finding of a remarkably efficient debenzylation of p‐methoxybenzyl amines.
Tuning the Redox Properties of a Nonheme Iron(III)–Peroxo Complex Binding Redox‐Inactive Zinc Ions by Water Molecules
Authors: Lee Yong‐Min , Bang Suhee , Yoon Heejung , Bae Seong Hee , Hong Seungwoo , Cho Kyung‐Bin , Sarangi Ritimukta , Fukuzumi Shunichi , Nam Wonwoo
Published: June 2015

Redox‐inactive metal ions play important roles in tuning chemical properties of metal–oxygen intermediates. Herein we report the effect of water molecules on the redox properties of a nonheme iron(III)–peroxo complex binding redox‐inactive metal ions. The coordination of two water molecules to a Zn2+ ion in (TMC)FeIII‐(O2)‐Zn(CF3SO3)2 (1‐Zn2+) decreases the Lewis acidity of the Zn2+ ion, resulting in the decrease of the one‐electron oxidation and reduction potentials of 1‐Zn2+. This further changes the reactivities of 1‐Zn2+ in oxidation and reduction reactions; no reaction occurred upon addition of an oxidant (e.g., cerium(IV) ammonium nitrate (CAN)) to 1‐Zn2+, whereas 1‐Zn2+ coordinating two water molecules, (TMC)FeIII‐(O2)‐Zn(CF3SO3)2‐(OH2)2 [1‐Zn2+‐(OH2)2], releases the O2 unit in the oxidation reaction. In the reduction reactions, 1‐Zn2+ was converted to its corresponding iron(IV)–oxo species upon addition of a reductant (e.g., a ferrocene derivative), whereas such a reaction occurred at a much slower rate in the case of 1‐Zn2+‐(OH2)2. The present results provide the first biomimetic example showing that water molecules at the active sites of metalloenzymes may participate in tuning the redox properties of metal–oxygen intermediates.
ChemInform Abstract: Crystal Structure and Properties of Tetragonal EuAg4In8 Grown by Metal Flux Technique.
Authors: Subbarao Udumula , Sarkar Sumanta , Peter Sebastian C.
Published: June 2015

Single crystals of EuAg4In8 are obtained from a melt of Eu, Ag, and In (as the flux) in the molar ratio of 1:1.3:8.7 (alumina crucible in evacuated silica tubes, 1000 °C, 5 h; 850 °C, 2 d).
ChemInform Abstract: Fe—Al—P—C—B Bulk Metallic Glass with Good Mechanical and Soft Magnetic Properties.
Authors: Wang Jianfeng , Cao Wenbo , Wang Liguo , Zhu Shijie , Guan Shaokang , Huang Lu , Li Ran , Zhang Tao
Published: June 2015

Fe77Al3(P,C,B)20 is fabricated by induction melting of the elements and pre‐alloyed Fe‐P (22.41 wt% P) and Fe‐B (17.24 wt% B) followed by melt spinning and Cu mold injection casting.
ChemInform Abstract: Monoclinic LaGa1‐xMnxGe2O7: A New Blue Chromophore Based on Mn3+ in the Trigonal Bipyramidal Coordination with Longer Apical Bond Lengths.
Authors: Saraswathy Divya , Rao P. Prabhakar , Sameera S. , James Vineetha , Raj Athira K. V.
Published: June 2015

Blue pigments of LaGa1‐xMnxGe2O7 are prepared by firing La2O3, Ga2O3, Mn2O3, and GeO2 in stoichiometric amounts using H3BO3 as a flux (Pt crucible, 1100 °C, 6 h).
ChemInform Abstract: Crystal Structure and Luminescence Properties of Bi3+ Activated Ca2Y3Sb3O14 Phosphors in Near UV Region.
Authors: Jiang Ziqiang , Yu Xiaochen , Gou Jin , Su Xinghua , Sun Zhihua , Duan Li
Published: June 2015

Ca2Y3‐xSb3O14: Bi3+x (x = 0.0225‐0.75) phosphors are prepared by firing stoichiometric amounts of CaCO3, Y2O3, Sb2O3, and Bi2O3 (Al2O3 crucible, 1400 °C, 8 h).
ChemInform Abstract: Superconductivity in Single Crystals of Lu3T4Ge13‐x (T: Co, Rh, Os) and Y3T4Ge13‐x (T: Ir, Rh, Os).
Authors: Rai Binod K. , Oswald Iain W. H. , Wang Jiakui K. , McCandless Gregory T. , Chan Julia Y. , Morosan E.
Published: June 2015

Single crystals of Lu3T4Ge13‐x (T: Co, Rh, Os) and Y3T4Ge13‐x (T: Ir, Rh, Os) are grown by a self‐flux method from mixtures of the elements in ratios of Lu(Y):T:Ge of 2:3:25 or 1:1:20 (1000‐1200 °C; slow cooling to 820‐960 °C) followed by decanting the surplus Ge flux.
ChemInform Abstract: Structure, Optical Properties, and Magnetism of Zn1‐xNixWO4 (0 ≤ x ≤ 1) Solid Solution.
Authors: Huang Hongwei , Liu Liyuan , Tian Na , Zhang Yihe
Published: June 2015

The Zn1‐xNixWO4 (0 ≤ x ≤ 1) solid solution is prepared by hydrothermal reaction of stoichiometric amounts of Zn(NO3)2, Ni(NO3)2, and Na2WO4 aqueous solutions (autoclave, 180 °C, 24 h) followed by annealing (500 °C, 1 h).
ChemInform Abstract: Phase Coexistence in NaTaO3 at Room Temperature; a High Resolution Neutron Powder Diffraction Study.
Authors: Knight Kevin S. , Kennedy Brendan J.
Published: June 2015

Time‐of‐flight room temperature high resolution neutron powder diffraction data of NaTaO3 show a phase coexistence of two orthorhombic structures (space groups Cmcm and Pbnm) which are obtained by a phase transition at ≈763 K and which coexist down to room temperature and probably to 0 K.
ChemInform Abstract: Liquidus Projection and Isothermal Section at 650 °C of Ternary Co—Sb—Ga System.
Authors: Chen Sinn‐wen , Chien Yuan‐chun , Chen Wei‐an , Chang Jui‐shen , Tseng Ssu‐ming , Snyder G. Jeffrey
Published: June 2015

Both, alloys quenched from the molten state with compositions of the entire Co—Sb—Ga regime and alloys equilibrated at 650 °C with compositions in the CoSb3—CoGa—Ga—Sb regime are prepared and analyzed.
ChemInform Abstract: Tantalum Nitride Nanorod Arrays: Introducing Ni—Fe Layered Double Hydroxides as a Cocatalyst Strongly Stabilizing Photoanodes in Water Splitting.
Authors: Wang Lei , Dionigi Fabio , Nguyen Nhat Truong , Kirchgeorg Robin , Gliech Manuel , Grigorescu Sabina , Strasser Peter , Schmuki Patrik
Published: June 2015

A NiFe layered double hydroxide (LDH) co‐catalyst coated Ta3N5 nanorod electrode is fabricated by vapor deposition of Al on a Ta foil followed by anodizing the Al layer in oxalic acid, (40 V, 0.5 h), pore widening of the as‐prepared porous Al2O3 by immersion in 5% aq.
ChemInform Abstract: Performance of Cobalt‐Free Double‐Perovskite NdBaFe2‐xMnxO5+δ Cathode Materials for Proton‐Conducting IT‐SOFC.
Authors: Mao Xinbo , Yu Tian , Ma Guilin
Published: June 2015

A series of NdBaFe2‐xMnxO5+δ (0.0 ≤ x ≤ 0.3) cathode materials are prepared by sol‐gel processing of a stoichiometric HNO3 solution of MnO, Nd2O3, Ba(NO3)2, and Fe(NO3)3 and citric acid at pH 5 followed by H2O evaporation, calcination (800 °C, 2 h), and hot pressing of the resultant material (50 MPa, 1200 °C, 5 h).
ChemInform Abstract: Enhanced Catalytic Activity for NO Oxidation over Ba Doped LaCoO3 Catalyst.
Authors: Zhou Chen , Feng Zijian , Zhang Yexin , Hu Lingjun , Chen Rong , Shan Bin , Yin Hongfeng , Wang Wei Guo , Huang Aisheng
Published: June 2015

A series of A‐side modified La1‐xBaxCoO3 (x = 0, 0.1, 0.2, 0.3) perovskites is prepared by a modified sol‐gel method using citric acid and EDTA as complexons with aqueous solutions of the metal nitrate precursors followed by drying and calcining in air (700 °C, 5 h).
ChemInform Abstract: Graphene‐Supported Substoichiometric Sodium Tantalate as a Methanol‐Tolerant, Non‐Noble‐Metal Catalyst for the Electroreduction of Oxygen.
Authors: Sebastian David , Baglio Vincenzo , Sun Shuhui , Tavares Ana C. , Arico Antonino S.
Published: June 2015

The graphene‐supported Na2Ta8O21‐x electrocatalyst (50 wt% Ta2O5, 50 wt% graphene) is obtained by sonicating graphene in an aqueous TaCl5 solution at pH 10.9 (adjusted with NaOH) followed by drying and heating under Ar (900 °C, 90 min).
ChemInform Abstract: Room Temperature Syntheses and Thermal Behaviors of Hydrogarnets Sr3M2(OH)12 (M: Al, Cr and Fe).
Authors: Chen Yun‐Feng , Yang Zhi , Li Yong‐Ming , Guo Jing , Fu Wen‐Fu , Wang Ying‐Xia , Liao Fu‐Hui , Li Jianye
Published: June 2015

Sr3M2(OH)12 (M = Al, Cr, Fe) are prepared by mechanical room temperature solid state reaction through quickly grinding mixtures of Al(NO3)3·9H2O or MCl3·6H2O (M: Cr, Fe), Sr(NO3)2, and 10 mol% excess solid NaOH.
ChemInform Abstract: New Quaternary Oxides with Both Families of Second‐Order Jahn—Teller (SOJT) Distortive Cations: Solid‐State Synthesis, Structure Determination, and Characterization of YNbTe2O8 and YNbSe2O8.
Authors: Kim Yeong Hun , Jeon Beom‐Yong , You Tae‐Soo , Ok Kang Min
Published: June 2015

YNbTe2O8 (I) and YNbSe2O8 (II) are prepared by solid state reaction of Y2O3, Nb2O5, and TeO2 or SeO2 (evacuated silica tubes, 900 °C, 2 d; cooling to 600 °C with a rate of 6 °C/h).
ChemInform Abstract: Cs(TaO2)3(SeO3)2 and Cs(TiOF)3(SeO3)2: Structural and Second Harmonic Generation Changes Induced by the Different d0‐TM Coordination Octahedra.
Authors: Cao Xue‐Li , Hu Chun‐Li , Kong Fang , Mao Jiang‐Gao
Published: June 2015

The new compounds (IV) and (VI) are characterized by single crystal XRD, IR and UV/VIS spectroscopy, second harmonic generation measurements, and DFT calculations.
ChemInform Abstract: Synthesis and Characterization of a Series of [M2(β‐SiW8O31)2] n‐ Clusters and Mechanistic Insight into the Reorganization of {β‐SiW8O31} into {α‐SiW9O34}.
Authors: Winter Ross S. , Long De‐Liang , Cronin Leroy
Published: June 2015

A series of {B‐β‐SiW8O31}‐based transition metal substituted polyoxometalates is synthesized using BHEP as an organic base to buffer the reactions.
ChemInform Abstract: Nanoscale Building Blocks in a Novel Lithium Arsenotungsten Bronze: Synthesis and Characterization.
Authors: Zhao Pei , Mangir Murshed M. , Huq Ashfia , Grossmann Henrike K. , Maedler Lutz , Alekseev Evgeny V. , Gesing Thorsten M.
Published: June 2015

Polycrystalline Li3AsW7O25 is obtained by solid‐state reaction of LiNO3, WO3, and As2O5 in the molar ratio of 6:14:1, resp.
ChemInform Abstract: Preparation and Properties of a New Ternary Phase Mg3+xNi7‐xB2 (0.17 ≤ x ≤ 0.66) and Its Cu‐Doping Effect.
Authors: Liao Chang‐Zhong , Dong Cheng , Shih Kaimin , Zeng Lingmin , He Bing , Cao Wenhuan , Yang Lihong
Published: June 2015

Mg3+xNi7‐xB2 (x = 0—0.66) phases are prepared by melting and annealing of the elements (Ta foil in stainless steel tube, 873 K, 5 h; 1073 K, 10 h).
ChemInform Abstract: A Novel Low Cost Non‐aqueous Chemical Route for Giant Dielectric Constant CaCu3Ti4O12 Ceramic.
Authors: Singh Laxman , Kim Ill Won , Woo Won Seok , Sin Byung Cheol , Lee Hyung‐il , Lee Youngil
Published: June 2015

Highly crystalline giant dielectric CaCu3Ti4O12 (CCTO) is prepared by combustion of a stoichiometric Me‐O‐(CH2)2‐OH solution of the metal nitrates and inexpensive TiO2 followed by sintering of the obtained CCTO powder (1050 °C, 30 h).
ChemInform Abstract: CuPN2: Synthesis, Crystal Structure, and Electronic Properties.
Authors: Pucher Florian J. , Hummel Franziska , Schnick Wolfgang
Published: June 2015

The first ternary copper phosphorus nitride CuPN2 is prepared from Cu3N and P3N5 by hot pressing (Walker‐type multianvil press, 5 GPa, 1000 °C).
ChemInform Abstract: Solid Supported 9‐Amino‐9‐deoxy‐epi‐quinine as Efficient Organocatalyst for Stereoselective Reactions in Batch and under Continuous Flow Conditions.
Authors: Porta Riccardo , Benaglia Maurizio , Coccia Francesca , Cozzi Franco , Puglisi Alessandra
Published: June 2015

The general applicability and the recyclability of the novel heterogeneous catalyst are demonstrated by batch reactions between carbonyl compounds and nitroolefins.
ChemInform Abstract: Solvent‐Induced Reversal of Enantioselectivity in the Synthesis of Succinimides by the Addition of Aldehydes to Maleimides Catalyzed by Carbamate‐Monoprotected 1,2‐Diamines.
Authors: Flores‐Ferrandiz Jesus , Fiser Bela , Gomez‐Bengoa Enrique , Chinchilla Rafael
Published: June 2015

A simple change in the polarity of the solvent allows both enantiomers of substituted succinimides to be obtained in the enantioselective conjugate addition reaction of aldehydes, mainly α,α‐disubstituted, to maleimides catalyzed by chiral carbamate‐monoprotected trans‐cyclohexane‐1,2‐diamines.
ChemInform Abstract: Homochiral L‐Prolinamido‐Sulfonamides and Their Use as Organocatalysts in Aldol Reactions.
Authors: Rojas Cabrera Haydee , Huelgas Gabriela , Hernandez Perez Julio M. , Walsh Patrick J. , Somanathan Ratnasamy , Anaya de Parrodi Cecilia
Published: June 2015

The synthesis of new chiral prolinamido‐sulfonamide catalysts based on a 9,10‐dihydro‐9,10‐ethanoanthracene frame and their application in aldol reactions are reported.
ChemInform Abstract: Synthesis of Several Polyethers Derived from BINOL and Their Application in the Asymmetric Borane Reduction of Prochiral Ketones.
Authors: Zhang An‐Lin , Yu Zeng‐da , Yang Li‐Wen , Yang Nian‐Fa
Published: June 2015

Several novel polyethylene glycol linked BINOL catalysts are prepared and employed to induce the enantioselective borane reduction of prochiral ketones.
ChemInform Abstract: The Diels—Alder Approach to Δ9‐Tetrahydrocannabinol Derivatives.
Authors: Glaeser Franziska , Broehmer Manuel C. , Hurrle Thomas , Nieger Martin , Braese Stefan
Published: June 2015

The Diels—Alder reaction of vinylchromene (I) with dienophiles (II) or (VI) provides the tricyclic key‐precursors (III) and (VII).
ChemInform Abstract: Rearrangement Reactions of 1,1‐Divinyl‐2‐phenylcyclopropanes.
Authors: Hay E. Ben , Zhang Hanmo , Curran Dennis P.
Published: June 2015

1,1‐Divinyl‐2‐phenylcyclopropanes are a class of substrates showing a rich array of both thermal and photochemical rearrangement reactions.
ChemInform Abstract: Hydrogenations at Room Temperature and Atmospheric Pressure with Mesoionic Carbene‐Stabilized Borenium Catalysts.
Authors: Eisenberger Patrick , Bestvater Brian P. , Keske Eric C. , Crudden Cathleen M.
Published: June 2015

1,2,3‐Triazolylidene‐based mesoionic carbene boranes are synthesized in a convenient one‐pot protocol from the corresponding triazolium salts, base, and borane.
ChemInform Abstract: In Tandem or Alone: A Remarkably Selective Transfer Hydrogenation of Alkenes Catalyzed by Ruthenium Olefin Metathesis Catalysts.
Authors: Zielinski Grzegorz Krzysztof , Samojlowicz Cezary , Wdowik Tomasz , Grela Karol
Published: June 2015

A mild method for the transfer hydrogenation of a wide range of alkenes showing high functional group tolerance and remarkable selectivity using a system of a ruthenium metathesis catalyst and HCOOH is developed.
ChemInform Abstract: Lewis Acid‐Catalyzed Electrophilic Trifluoromethylthiolation of (Hetero)Arenes.
Authors: Wang Qiang , Qi Zisong , Xie Fang , Li Xingwei
Published: June 2015

Selective trifluoromethylthiolation of electron‐rich arenes and olefins is achieved in the presence of a Lewis acid catalyst such as Fe(III) or Au(III).
ChemInform Abstract: A Versatile and One‐Pot Strategy to Synthesize α‐Amino Ketones from Benzylic Secondary Alcohols Using N‐Bromosuccinimide.
Authors: Guha Somraj , Rajeshkumar Venkatachalam , Kotha Surya Srinivas , Sekar Govindasamy
Published: June 2015

A variety of α‐amino ketones including some psychoactive drugs such as amfepramone (VIId) and pyrovalerone are efficiently obtained by a metal‐free one‐pot synthesis from readily available benzylic secondary alcohols and amines.
ChemInform Abstract: Allylic Aminations with Hindered Secondary Amine Nucleophiles Catalyzed by Heterobimetallic Pd—Ti Complexes.
Authors: Walker Whitney K. , Anderson Diana L. , Stokes Ryjul W. , Smith Stacey J. , Michaelis David J.
Published: June 2015

This method is suitable for the inter‐ and intramolecular amination of allylic chlorides.
ChemInform Abstract: Catalytic Tandem Markovnikov Hydroamination‐Alkynylation and Markovnikov Hydroamination—Hydrovinylation.
Authors: Palchak Zachary L. , Lussier Daniel J. , Pierce Conor J. , Yoo Hoseong , Larsen Catharine H.
Published: June 2015

A tandem hydroamination‐alkynylation reaction to furnish tetrasubstituted propargylic amines is developed.
ChemInform Abstract: Cross‐Dehydrogenative Coupling of Azoles with α‐C(sp3)—H of Ethers and Thioethers under Metal‐Free Conditions: Functionalization of H—N Azoles via C—H Activation.
Authors: Singh Parvinder Pal , et al.
Published: June 2015

This method is suitable for a broad variety of azoles, e.
ChemInform Abstract: Cobalt‐Catalyzed C—H Cyanation of (Hetero)arenes and 6‐Arylpurines with N‐Cyanosuccinimide as a New Cyanating Agent.
Authors: Pawar Amit B. , Chang Sukbok
Published: June 2015

The title reaction gives monocyanated products with high selectivity and excellent functional group tolerance.
ChemInform Abstract: Copper(I)—Taniaphos Catalyzed Enantiodivergent Hydroboration of Bicyclic Alkenes.
Authors: Lee Hyesu , Lee Byoung Yoon , Yun Jaesook
Published: June 2015

Copper‐catalyzed enantiodivergent hydroboration of bicyclic alkenes is achieved using the same chiral ligand (TPO) but different boron sources.
ChemInform Abstract: Silylation of C—H Bonds in Aromatic Heterocycles by an Earth‐Abundant Metal Catalyst.
Authors: Toutov Anton A. , Liu Wen‐Bo , Betz Kerry N. , Fedorov Alexey , Stoltz Brian M. , Grubbs Robert H.
Published: June 2015

This is a simple method for the C—H silylation of heteroaromatic compounds using potassium tert‐butoxide as a readily available and inexpensive catalyst.
ChemInform Abstract: Rhodium(III)‐Catalyzed Oxidative Alkenylation of 1,3‐Dithiane‐Protected Arenecarbaldehydes via Regioselective C—H Bond Cleavage.
Authors: Unoh Yuto , Hirano Koji , Satoh Tetsuya , Miura Masahiro
Published: June 2015

The 1,3‐dithiane group serves as an effective directing group to allow the ortho‐selective monoalkylation.
ChemInform Abstract: Enantioselective Preparation of 3‐Arylcycloalkylamines by Rhodium‐Catalyzed 1,4‐Addition and Subsequent Stereodivergent Reduction.
Authors: Gebhardt Sandra , Mueller Christian H. , Westmeier Johannes , Harms Klaus , von Zezschwitz Paultheo
Published: June 2015

The reaction of α,β‐unsaturated N‐sulfonylimines with arylzinc chlorides is combined with a suitable reduction method to provide 3‐arylcycloalkylamines with high diastereo‐ and enantioselectivities.
ChemInform Abstract: A Versatile Difluorovinylation Method: Cross‐Coupling Reactions of the 2,2‐Difluorovinylzinc—TMEDA Complex with Alkenyl, Alkynyl, Allyl, and Benzyl Halides.
Authors: Ichitsuka Tomohiro , Takanohashi Tsuyoshi , Fujita Takeshi , Ichikawa Junji
Published: June 2015

Title zinc complex (II) is synthesized and applied to transition metal‐catalyzed cross‐coupling reactions with a wide range of organic halides yielding 2,2‐difluorovinyl compounds.
ChemInform Abstract: A Ligand‐Free Strategy for the Copper‐Catalyzed Direct Alkynylation of Trifluoromethyl Ketones.
Authors: Wang Lei , Liu Ning , Dai Bin , Ma Xiaowei , Shi Lei
Published: June 2015

An efficient and inexpensive direct alkynylation of trifluoromethyl ketones (I) is developed without using any additional ligands.
ChemInform Abstract: Synthesis of Acyloxy‐Semicyclic Dienes Using an Enyne Metathesis/Ring Closing Metathesis Approach.
Authors: Kueh Jui Thiang Brian , Moodie Lindon W. K. , Lucas Nigel T. , Larsen David S.
Published: June 2015

A new approach for the synthesis of semicyclic dienes from enyne substrates and vinyl esters through an enyne metathesis/ring closing metathesis sequence is developed.
ChemInform Abstract: Difluorohomologation of Ketones.
Authors: Kosobokov Mikhail D. , Levin Vitalij V. , Struchkova Marina I. , Dilman Alexander D.
Published: June 2015

The one‐pot three‐step sequence for the difluorohomologation of ketones involves silylation, difluorocyclopropanation of silyl enol ethers followed by highly regioselective ring opening of cyclopropane intermediates.
ChemInform Abstract: Vanadyl Species‐Catalyzed Complementary β‐Oxidative Carbonylation of Styrene Derivatives with Aldehydes.
Authors: Yang Wen‐Chieh , Weng Shiue‐Shien , Ramasamy Anandhan , Rajeshwaren Gobi , Liao Yi‐Ya , Chen Chien‐Tien
Published: June 2015

The oxidative coupling of styrenes with aldehydes using tBuOOH as the oxidant is studied.
ChemInform Abstract: Highly Regioselective Osmium‐Catalyzed Hydroformylation.
Authors: Wu Lipeng , Liu Qiang , Spannenberg Anke , Jackstell Ralf , Beller Matthias
Published: June 2015

The osmium‐catalyzed hydroformylation of alkenes (I) proceeds with high regioselectivity.
ChemInform Abstract: Acid Mediated Deprotection of N‐Isopropyl Tertiary Amides.
Authors: Lorenc Chris , Reeves Jonathan T. , Busacca Carl A. , Senanayake Chris H.
Published: June 2015

Thermal reaction of N‐isopropyl tertiary amides in MesOH results in selective removal of the N‐isopropyl group.
ChemInform Abstract: Simple Preparation of Aryltributylstannanes and Its Application to One‐Pot Synthesis of Diaryl Ketones.
Authors: Oikawa Asuka , Kindaichi Gan , Shimotori Yasutaka , Okimoto Mitsuhiro , Hoshi Masayuki
Published: June 2015

Aryltributylstannanes are prepared under solvent‐free conditions from the corresponding arylboronic acids.
ChemInform Abstract: Diversified Facile Synthesis of Benzimidazoles, Quinazolin‐4(3H)‐ones and 1,4‐Benzodiazepine‐2,5‐diones via Palladium‐Catalyzed Transfer Hydrogenation/Condensation Cascade of Nitro Arenes under Microwave Irradiation.
Authors: Zhu Kaicheng , Hao Jian‐Hong , Zhang Cheng‐Pan , Zhang Jiajun , Feng Yiqing , Qin Hua‐Li
Published: June 2015

Title derivatives of quinazolin‐4(3H)‐one [(III), (V), and (VII)], benzimidazole [(IX) and (XI)], and 1,4‐benzodiazepine‐2,5‐dione (XIII) are efficiently synthesized through a one‐pot procedure in triethylamine—formic acid azeotropic mixture under microwave irradiation.
ChemInform Abstract: Convenient and Efficient Synthesis of Disubstituted Piperazine Derivatives by Catalyst‐Free, Atom‐Economical and Tricomponent Domino Reactions.
Authors: Dong Hong‐Ru , Chen Zi‐Bao , Li Rong‐Shan , Dong Heng‐Shan , Xie Zhi‐Xiang
Published: June 2015

Synthesis of disubstituted piperazine derivatives is accomplished by a one‐pot ring opening and tri‐component domino reaction.
ChemInform Abstract: Ligand‐Controlled Regiodivergent Palladium‐Catalyzed Decarboxylative Allylation Reaction to Access α,α‐Difluoroketones.
Authors: Yang Ming‐Hsiu , Orsi Douglas L. , Altman Ryan A.
Published: June 2015

Complementary palladium‐catalyzed decarboxylative allylation reactions are developed to provide linear and branched α‐allyl‐α,α‐difluoroketones.
ChemInform Abstract: Highly Enantioselective Direct Asymmetric Aldol Reaction Catalyzed by 4,5‐Methano‐L‐proline.
Authors: Zhang Yukun , Zhu Jun , Yu Na , Yu Han
Published: June 2015

The reaction can be scaled up.
ChemInform Abstract: An Insight into the Synthesis of Novel Aryl‐Substituted Alicyclic β‐Amino Acid Derivatives Through Substrate‐Directed Palladium‐Catalyzed Regio‐ and Stereoselective Cross‐Coupling.
Authors: Nonn Melinda , Kiss Lorand , Haenninen Mikko M. , Fueloep Ferenc
Published: June 2015

Different types of aryl‐substituted cyclic β‐amino acid derivatives are obtained by palladium coupling under Heck conditions depending on the structure of the starting five‐ or six‐membered β‐aminocycloalkenecarboxylate and the position of the double bond.