bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS VALUE ENGINEERING PADA PROYEK PERUMAHAN X DI TANGERANG SELATAN
Authors: Chandra Robert , Sutandi Arianti , Anondho Basuki
Published: June 2023

The cost of building a construction project is very important and requires good control so that the project can run according to plan. The research was conducted in one of the residential housing projects located in South Tangerang, the cost for architectural work is greater than other costs, for that an engineering value assessment was carried out to find out the cost savings of architectural work in project x, by identifying which work tends to incur high costs through the phase information, construction phase, analysis phase, development phase and recommendation phase, and using paired comparison and decision matrix methods. Furthermore, the determining factors are sought to be used as a substitute for the design. The cost of working on a red brick wall for a 7x10 type house is Rp. 2,468,993,947.28, after doing value engineering with alternative 1 (replacing red brick walls with bricks) a cost of Rp. 2,048,059,320.60 savings of Rp. 420,934,626.68 (17.04% of the total cost of wall work) and for a 7×12 type house a savings of Rp. 643,039,928.39 (17.60% of the total wall work cost).
AbstrakBiaya pembangunan proyek konstruksi sangat penting dan memerlukan kontrol yang baik agar proyek dapat berjalan sesuai rencana. Penelitian dilakukan di salah satu proyek perumahan residensial yang terletak di Tangerang Selatan, biaya untuk pekerjaan arsitektural lebih besar dari biaya lainnya, untuk itu dilakukan penilaian value engineering untuk mengetahui penghematan biaya pekerjaan arsitektural di proyek x, dengan mengidentifikasi pekerjaan mana yang cenderung mengeluarkan biaya tinggi melalui fase informasi, fase konstruksi, fase analisis, fase pengembangan dan fase rekomendasi, dan menggunakan metode paired comparison dan decision matrix. Selanjutnya dicari faktor penentu untuk digunakan sebagai pengganti desain. Pengeluaran biaya pekerjaan dinding bata merah untuk rumah tipe 7×10 adalah sebesar Rp. 2.468.993.947,28, setelah dilakukan value engineering dengan alternatif 1 (mengganti dinding bata merah dengan dinding batako) didapatkan biaya sebesar Rp. 2.048.059.320,60 didapatkan penghematan Rp. 420.934.626,68 (17.04% dari total biaya pekerjaan dinding) dan untuk rumah tipe 7×12 didapatkan penghematan sebesar Rp. 643.039.928,39 (17.60% dari total biaya pekerjaan dinding).
Psi-entific Approach to Post-Mortem Survival: Employing the Multiple Sources of Psi (MSoP) and Discarnate Psi Hypotheses in the Calculation of a Drake-S Equation
Authors: Merlin Serge
Published: June 2023

The continued investigations of the paranormal facilitated the development of novel theories and methodologies. Psi functioning of the living and the deceased in survival phenomena suggested the living agent psi (LAP) and discarnate psi hypotheses, but neither has demonstrated sufficient explanatory power to claim superiority in explaining survival data. Mediumship studies cannot determine whether paranormal information is sourced by means of discarnate psi or LAP, presenting the source-of-psi problem. Anomalous information can be obtained from joint sources (LAP, survival, or some other source), which supports the multiple sources of psi (MSoP) hypothesis. The maximized explanatory potential of the MSoP hypothesis makes the inclusion of the LAP and discarnate psi factors in the calculation of a Drake-S equation for post-mortem survival required and appropriate. This paper concludes that 1) the aggregate effect of skeptical explanations for survival was calculated at 65.6%, leaving 35.4% to paranormal explanations, which contradicts skeptical claims and is inconsistent with the existing laws of conventional science; 2) 16% of paranormal experiences reported among the general population appeared genuine; and 3) the calculated purified probability for all paranormal phenomena equaling 40% can be attributed to paranormal causes. This suggests reasonable plausibility of the survival hypothesis. To refine the existing factors and find new empirical factors related to known confounds and anomalous effects, future research should include more robust procedures and methods of data selection, gathering, and analysis.
Modeling Public Concerns for Unmanned Aerial System Operations in the National Airspace System
Authors: Philpott Robert , Winer Eliot
Published: June 2023

The Unites States commercial unmanned aerial system (UAS) market was valued at $99.6 million in 2020 and is projected to reach $3.7 billion by 2030. Applications for these commercial UAS range from risk mitigation and surveillance to package delivery. Coupled with these emerging applications are the unique factors that arise with a commercial UAS’s compact size and low-altitude flights among the civilian populace. In this work, a value model was created to attempt to aid in determining the infringement of a UAS operation configuration on a civilian environment. Value functions were developed in an additive model that measures infringement (a UAS’s encroachment or trespass on a right or privilege of a civilian) based on these attributes. The resulting value model was tested by running 100,000 random simulations. Analysis of the simulation results and sensitivity analysis of the model showed that fleet size, proximity, duration of the operation within a certain proximity, and total operation duration were the attributes that drove a UAS operation’s infringement on an environment. A use case of an Amazon delivery application was then examined. This is a realistic scenario simulated to study if duration of an operation and time near a structure are kept to a minimum, the infringement of an operation remained low. This study provides initial determination of how infringement of UAS can be quantified and what infringement values may look like for different operational scenarios.
DAMPAK BEKERJA DARI RUMAH (WORK FROM HOME) DI INSTANSI PEMERINTAHAN
Authors: Sufri Nuryamin  , Widuri Wulandari
Published: June 2023

Penelitian ini bertujuan untuk mengetahui bagaimana dampak bekerja dari rumah (Work From Home) yang dilakukan oleh instansi pemerintahan khususnya pada lembaga Kementerian Desa, Pembangunan Daerah Tertinggal dan Transmigrasi (Kemendes PDTT). Penerapan bekerja dari rumah merupakan sesuatu yang baru terjadi di lingkungan pemerintahan. Pada awal  pandemic Covid-19, baik instansi pemerintahan maupun swasta diharuskan untuk Work From Home (WFH). Jam kerja dan tanggung jawab para Aparatur Sipil Negara (ASN) berubah karena adanya penerapan WFH. Kementerian Desa, Pembangunan Daerah Tertinggal dan Transmigrasi (Kemendes PDTT), merupakan instansi pemerintahan yang memiliki tanggung jawab salah satunya adalah melakukan pengawasan ke desa-desa dan daerah tertinggal di seluruh Indonesia, bersosialisasi dengan masyarakat desa. Namun dengan adanya WFH, mempengaruhi jam kerja dan tanggung jawab ASN Kemendes PDTT. Jenis penelitian ini yaitu deskriptif kualitatif dengan menggunakan aplikasi Nvivo dalam pengelolaan data wawancara dan dokumentasi. Hasil dari penelitian ini yaitu dampak bekerja dari rumah (Work From Home) di instansi pemerintahan, khususnya Kemendes PDTT dilihat dari tiga dimensi. Dimensi pertama yaitu dari dimensi ekonomi yaitu adanya pengurangan belanja pegawai karena tidak adanya pengeluaran untuk biaya perjalanan dinas dan juga biaya pengadaaan barang untuk rapat seperti pulpen, buku dan lainnya. Dari dimensi teknologi, para ASN lebih banyak menggunakan teknologi saat bekerja dengan demikian adanya penambahan pengetahuan terkait teknologi, dan yang terakhir sosial, karena keterbatasan gerak, kurangnya kunjungan ke desa-desa dan daerah hal ini mengakibatkan kurangnya interaksi dengan masyarakat secara langsung
MEKANISME PEMUNGUTAN PAJAK KENDARAAN BERMOTOR DI PROVINSI DKI JAKARTA
Authors: Indrayanti Ana Maisyaroh , Amy Yayuk Sri Rahayu
Published: June 2023

Pemungutan pajak di Indonesia tidak hanya menjadi kewenangan Pemerintah Pusat, tetapi juga Pemerintah Daerah. Kewenangan yang besar dalam menyelenggarakan pemerintahan dan melayani kepentingan masyarakat idealnya juga disertai dengan semakin besarnya kewenangan dalam menetapkan pajak dan retribusi. Akan tetapi kenyataanya daerah tidak memiliki keleluasaan dalam menetapkan tarif pajak dan retribusi. Adapun tujuan dari penelitian ini adalah untuk mengetahui mekanisme pemungutan pajak khususnya Pajak Kendaraan Bermotor, usaha yang dilakukan, serta tantangan yang dihadapi oleh Provinsi DKI Jakarta dengan menggunakan metode penelitian kualitatif dan studi Pustaka. Sebagai Ibu Kota Negara Indonesia, Provinsi DKI Jakarta memiliki mobilitas yang sangat tinggi sehingga menyebabkan tingginya tingat kemacetan lalu lintas. Hal ini menyebabkan Pajak Kendaraan Bermotor menjadi sumber pendapatan terbesar Provinsi DKI Jakarta. Untuk meningkatkan Pendapatan Asli Daerah (PAD), Provinsi DKI Jakarta menetapkan Perda Nomor 8 Tahun 2010 tentang Pajak Kendaraan Bermotor dengan diberlakukannya tarif pajak progresif kendaraan bermotor pribadi. Tarif yang dikenakan pada kendaraan bermotor pertama sebesar 1,50% (satu koma lima nol persen), kedua sebesar 2% (dua persen), ketiga sebesar 2,50% (dua koma lima nol persen), keempat dan seterusnya sebesar 4% (empat persen). Hal ini membawa keuntungan bagi Provinsi DKI Jakarta, yaitu pada tahun 2018 melalui Badan Pajak dan Retribusi Daerah memperoleh penerimaan sebesar 5,69 triliun.
MEKANISME PENYELESAIAN KONFLIK INTERNAL DI PARTAI DEMOKRASI INDONESIA-PERJUANGAN KOTA BATU
Authors: Suci Navasari  , Ihsan Nuralim
Published: June 2023

Problem umum yang sering menghinggapi partai politik adalah konflik internal, dan kadang yang menghancurkan partai politik (parpol) itu sendiri. Namun demikian jarang sekali ada partai politik yang mempunyai mekanisme penyelesaian konflik internal sehingga banyak partai yang dilanda konflik mengalami perpecahan. Tujuan penelitian ini untuk mengkaji mekanisme penyelesaian konflik internal di tubuh Partai Demokrasi Indonesia - Perjuangan Kota Batu. Metode penelitian yang digunakan dalam penelitian ini adalah metode deskriptif kualitatif. Sementara pengambilan data dilakukan melalui observasi, wawancara dan pendekatan historical researct. Hasil penelitian ini menunjukan bahwa PDI-P Kota Batu rendah terjadi konflik internal yang besar. Disamping itu struktur kepengurusan PDI-P Kota Batu banyak bergantung kepada keputusan-keputusan dari pimpinan pusat PDI-P. Dengan demikian bisa disimpulkan bahwa PDI-P memiliki mekanisme penyelesaian konflik yang efektif dibuktikan dari rendahnya khasus konflik yang terjadi. Oleh karena itu PDI-P membutuhkan otonomi yang lebih besar kepada daerah untuk melakukan manajemen organisasi. Pemerintah perlu membuat peraturan perundangan yang memberikan jaminan bagi partai politik agar tidak terjadi konflik yang diakibatkan konflik internal.
TINJAUAN YURIDIS TENTANG PERSAMAAN DAN PERBEDAAN SISTEM PEMERINTAHAN DAERAH OTONOM DENGAN SISTEM PEMERINTAHAN NEGARA BAGIAN
Authors: Cecep Cahya Supena  , Diwan Pramulya
Published: June 2023

Susunan negara di seluruh dunia secara umum dapat dibagi ke dalam 2 jenis, yaitu Negara Unitaris (Kesatuan) dan Negara Federasi (Serikat). Negara Unitaris terdiri dari 2 (dua) sistem, yaitu Negara Unitaris yang menerapkan sistem Sentralisasi dan Negara Unitaris  yang menerapkan sistem Desentralisasi. Di Negara Unitaris yang menerapkan sistem sentralisasi,  pemerintah pusat adalah sebagai penyelenggara seluruh kegiatan pemerintahan dalam negara, sedangkan keberadaan pemerintah daerah hanya sebagai pelaksana kebijakan-kebijakan yang dibuat oleh pemerintah pusat. Sedangkan untuk di Negara Unitaris yang menerapkan sistem desentralisasi, kepada setiap daerah diberi hak otonomi, yaitu hak / wewenang bagi pemerintah daerah untuk bisa  mengatur dan mengurus daerahnya sendiri menurut prakarsa/inisiatif sendiri. Sekalipun demikian pemerintah daerah tetap harus tunduk  dan patuh pada kebijakan-kebijakan yang dikeluarkan oleh pemerintah pusat. Selanjutnya yang dimaksud dengan  Negara Federasi (Serikat)  ialah negara yang merupakan gabungan dari negara-negara bagian.  Negara-negara  bagian ini memiliki wewenang mengatur dan mengurus kepentingan negaranya masing-masing,  seperti  halnya wewenang yang diberikan kepada daerah otonom. Secara sepintas terlihat bahwa antara daerah otonom yang ada pada negara unitaris yang menerapkan sistem desentralisasi dengan negara bagian yang ada pada negara serikat, memiliki beberapa persamaan dalam penyelenggaraan sistem pemerintahan disamping adanya beberapa perbedaan.
KEHADIRAN PARTAI GELOMBANG RAKYAT INDONESIA SEBAGAI MANAJEMEN KONFLIK INTERNAL PARTAI POLITIK
Authors: Muhammad Sidiq  , Robi Cahyadi Kurniawan  , Arizka Warganegara  , Barokah Fitria
Published: June 2023

Konflik di tubuh partai politik adalah suatu hal yang tidak dapat dihindari, dan tidak jarang konflik internal dapat menciptakan perpecahan partai. Tulisan ini betujuan menganalisis bagaimana konflik internal partai PKS dapat melahirkan partai baru (Gelora). Tulisan ini menggunakan studi kepustakaan, dengan data yang digunakan adalah buku dan laporan ilmiah primer atau asli yang terdapat di dalam artikel atau jurnal yang berkaitan dengan konflik intenal partai politik dan pelembagaan partai politik. Berdasarkan hasil analisis, tulisan ini menjelaskan kelahiran partai Gelora disebabkan adanya perbedaan ideologi politik antara Anis Matta dan Hilmi Aminudin, dan pembaharuan yang di inginkan Anis Matta mendapat penolakan dari kader PKS. Melihat pelembagaan Partai Keadilan Sejahtera (PKS) masih terbilang rendah, karena partai tidak dapat mengatasi konflik internalnya sendiri sehingga menciptakan perpecahan dan melahirkan partai baru (Partai Gelora). Bentuk manajemen konflik yang diambil oleh pihak berkonflik yaitu dengan mendirikan partai baru yaitu gelora. Dengan kata lain, konflik tidak akan berlajut dalam internal, karena ada pihak yang memutuskan pecah partai.
Pedagogical tools for the formation of patriotism of students in the physical culture and sports environment
Authors: Шульгин В.В. , Шаронов А.А.
Published: June 2023

Формирование патриотизма у обучающихся является одной из главных задач современного образования. В настоящее время, формирование патриотических чувств и гражданской позиции становится все более актуальным в современном обществе. Физическая культура и спорт являются важными средствами для достижения этой цели, так как они позволяют не только развивать физические качества человека, но и формировать его мировоззрение и общественные убеждения. Физкультурные вузы, которые занимаются подготовкой специалистов в области физической культуры и спорта, имеют особую роль в формировании патриотических чувств у студентов. В рамках учебного процесса, они могут использовать различные педагогические инструменты и методы для развития гражданской позиции и национальной идентичности у своих студентов. Цель данной статьи заключается в описании педагогического инструментария формирования патриотизма обучающихся в условиях физкультурного вуза. В рамках этой статьи будет рассмотрено, какие функции выполняет формирование патриотизма в физкультурно-спортивной среде, как это влияет на студентов и какие методы могут быть использованы для формирования патриотических чувств у студентов физкультурных вузов. Патриотизм является многогранным явлением и его формирование не может быть достигнуто только через физическую культуру и спорт. Однако, физкультурные вузы имеют значительный потенциал для развития патриотизма у своих студентов и могут сделать важный вклад в общественную жизнь и развитие своей страны.

The formation of patriotism among students is one of the main tasks of modern education. Currently, the formation of patriotic feelings and citizenship is becoming more and more relevant in modern society. Physical culture and sports are important means to achieve this goal, as they allow not only to develop a person's physical qualities, but also to form his worldview and social beliefs. Physical education universities that train specialists in the field of physical culture and sports have a special role in the formation of patriotic feelings among students. As part of the educational process, they can use various pedagogical tools and methods to develop citizenship and national identity among their students. The purpose of this article is to describe the pedagogical tools for the formation of patriotism of students in the conditions of a physical education university. Within the framework of this article, it will be considered what functions the formation of patriotism in the physical culture and sports environment performs, how it affects students and what methods can be used to form patriotic feelings among students of physical education universities. Patriotism is a multifaceted phenomenon and its formation cannot be achieved only through physical culture and sports. However, physical education universities have a significant potential for the development of patriotism among their students and can make an important contribution to the social life and development of their country.
Elucidating Functional Group Presence by Analyzing IR Spectra with 1-Dimensional Convolutional Neural Networks
Authors: Tang Ryan
Published: June 2023

This paper presents a novel solution to the problem of IR spectrum interpretation by applying a 1-dimensional convolutional neural network to classify molecular spectra as either containing a functional group or not containing a functional group. 16 mod- els were trained using a single general model architecture, and 11 were highly effective with accuracy, precision, recall, F1, and AUC scores, all greater than 90%. Phenome- nal classification performance was achieved on aldehydes and ketones, where previous attempts have struggled. Furthermore, a tool was developed to generate saliency maps for each model, allowing for the analysis and study of how the model interprets the IR spectra to make classifications. Our results have applications in fields such as the pharmaceutical industry and drug development, as well as the rapid assay screening of environmental pollutants while being generalizable to be a competitive option for any high-volume IR spectroscopy screening process.
Weak and Strong Coupling Properties of Surface Excitons
Authors: Dutta Arpan , Toppari J. Jussi
Published: June 2023

With high enough doping concentrations organic dye doped polymer materials exhibit negative real part of the permittivity within an energy range just above their material absorption, incurring surface exciton modes at these energies. Here, we report how such modes can be used to realize strong light-matter coupling with photoactive molecules. Our simulations reveal that surface excitons can facilitate strong coupling in terms of induced transparency, however, the polaritons may not be visible in the absorption since they can easily be located outside of the narrow negative permittivity regime. Moreover, we show that the surface exciton modes cannot couple strongly with the surface plasmons. Our findings shed light on the weak and strong coupling properties of surface excitons.
Active Learning of Ternary Alloy Structures and Energies
Authors: Deshmukh Gaurav , Wichrowski Noah J. , Evangelou Nikolaos , Ghanekar Pushkar G. , Deshpande Siddharth , Kevrekidis Ioannis G. , Greeley Jeffrey
Published: June 2023

High-throughput screening of catalysts using first-principles methods, such as density functional theory (DFT), has traditionally been limited by the large, complex, and multidimensional nature of the associated materials spaces. However, machine learning models with uncertainty quantification have recently emerged as attractive tools to accelerate the navigation of these spaces in a data-efficient manner, typically through active learning-based workflows. In this work, we combine such an active learning scheme with a dropout graph convolutional network (dGCN) as a surrogate model to explore the complex materials space of high-entropy alloys (HEAs). Specifically, we train the dGCN on the formation energies of disordered binary alloy structures in the Pd-Pt-Sn ternary alloy system and utilize the model to make and improve predictions on ternary structures. To do so, we perform reduced optimization over ensembles of ternary structures constructed based on two coordinate systems: (a) a physics-informed ternary composition space, and (b) data-driven coordinates discovered by the manifold learning scheme known as Diffusion Maps. Inspired by statistical mechanics, we derive and apply a dropout-informed acquisition function to select ensembles from which to sample additional structures. During each iteration of our active learning scheme, a representative number of crystals that minimize the acquisition function is selected, their energies are computed with DFT, and our dGCN model is retrained. We demonstrate that both of our reduced optimization techniques can be used to improve predictions of the formation free energy, the target property that determines HEA stability, in the ternary alloy space with a significantly reduced number of costly DFT calculations compared to a high-fidelity model. However, the manner in which these two disparate schemes converge to the target property differs: the physics-based scheme appears akin to a depth-first strategy, whereas the data-driven scheme appears more akin to a breadth-first approach. Both active learning schemes can be extended further to incorporate greater number of elements, surface structures, and adsorbate motifs.
Retrieval of atmospheric trace gases from satellite infrared limb sounding data
Authors: Cai Shaomin , Zhang Weijia , Zhao Yizhou
Published: June 2023

The Michelson Interferometer for Passive Atmospheric Sounding (MIPAS) instrument which operated in the near-to-mid infrared on the Envisat satellite from 2002–2012 is a Fourier-transform spectrometer for the measurement of high-resolution atmospheric emission spectra at the Earth’s limb. The initial operational products are profiles of temperature, H2O, O3, CH4, N2O, HNO3, and NO2, and this list is extended to include the important GHG (greenhouse gases) and ODS (ozone depleting substances) species using MORSE (orbital retrieval processor). This paper discusses retrievals of minor trace species of HCFC-22, HOCl, OCS, C2H6, COF2, HCN, CF4, SF6, and CCl4. Preliminary zonal mean results of these retrievals are satisfactory except for HCN and CF4 species. We then use MIPAS to estimate the total F and Cl budget in the atmosphere. Comparisons with SLIMCAT are also discussed, with the results consistent. Finally, we focus on improving the retrieval method for minor trace species, COF2, by adjusting correlation length and a priori constraint, as well as the chi-square method introduced to analyze noise. Tests have shown that our improvement could get more information from the measurements.
ПСИХІЧНЕ ЗДОРОВ’Я ВІЙСЬКОВОСЛУЖБОВЦІВ
Authors: Коструба Наталія
Published: June 2023

Мета. Стаття містить теоретичний огляд досліджень психічного здоров’я військовослужбовців, основних ризиків щодо втрати ментального благополуччя.

Методи. Огляд здійснено із застосуванням теоретичних методів наукових досліджень, а саме аналізу, синтезу, структурування та систематизації інформації.

Результати. Дослідження психічного здоров’я військових часто концентрують увагу на посттравматичному стресовому розладі (ПТСР). Проте, у наукових працях підкреслюється стійкий взаємозв’язок між ПТСР і підвищеними ризиками фізичних проблем зі здоров’ям, вживання/зловживання психоактивними речовинами, самогубства, бездомності та агресії/насильства для ветеранів. Праця військовослужбовців постійно пов’язана із стресом. Науковці визначили шість основних вимірів стресу виконання військових операцій: ізольованість, двозначність, безсилля, нудьга та небезпека, а також робоче навантаження. Сучасна війна із розвитком технологій залишає весь військовий персонал під постійною загрозою атаки, якщо раніше вважалось, що найбільш травматичним є перебування на «передовій». Військова служба може зіткнутися з досвідом, який підриває основне почуття людяності та порушує глобальні цінності та переконання. Моральна шкода є новою конструкцією для більш повного охоплення багатьох можливих психологічних, етичних і духовних/екзистенційних викликів серед людей, які служили в сучасних війнах, та інших професійних груп, які постраждали від травм.

Висновки. За результатами теоретичного огляду найбільшими ризиками для психічного здоров’я військовослужбовців є посттравматичний стресовий розлад, депресія, тривожні розлади, моральна травма, складне горе, почуття провини, суїцидальні схильності. Основними стресовими чинниками у професії військового є: моральні дилеми, умови постійної небезпеки і загрози життю, значне робоче навантаження, відносна ізольованість, невизначеність, втрати і спостереження за стражданнями інших людей.
Denetim Kalitesi Çerçeveleri: Ülkelerarası Bir Karşılaştırma
Authors: YAROĞLU Zeynep
Published: June 2023

Bu çalışma hem düzenleyicilerin hem akademisyenlerin otuz yılı aşkın süredir gündeminde yer alan ve fakat tanımı ve ölçümü üzerinde bir uzlaşma sağlanamamış olan denetim kalitesi ile ilgili dünyanın çeşitli ülkelerinde geliştirilmekte olan denetim kalitesi çerçevelerini ortaya koyan genel bir bakış sunmaktadır. Türkiye’de bu konuda düzenleyici kurumlar tarafından başlatılan henüz bir girişim olmaması ve Türkçe literatürde çerçevelerin ele alınmamış olması bu çalışmanın çıkış noktasını oluşturmaktadır. Denetim kalitesi çerçevesinde yer alan denetim kalitesi göstergeleri, farklı denetim şirketleri arasında karşılaştırılabilirliği ve şeffaflığı artırabilmektedir. Bir diğer önemli potansiyel faydası ise, örneğin bir denetim şirketi seçerken yönetişimden sorumlu olanlar ve denetim komiteleri için, somut bir rekabet unsuru haline gelebilecek olmasıdır. Böylece denetim şirketleri bağımsız denetim ücreti yerine denetim kalitesi göstergeleri üzerinden rekabet avantajı sağlamayı hedefleyeceklerdir. Çerçevelerin birçoğunun kural bazlı olduğu ve hem nicel hem nitel göstergeler içerdiği söylenebilmektedir. En sık yer verilen göstergeler arasında denetim saati, eğitim saati, bağımsız denetçi devir hızı gibi nicel ve denetim kalitesinin gözden geçirilmesi gibi karma göstergeler dikkati çekmektedir. Denetim kalitesinin objektif olarak değerlendirilmesi, hangi perspektiften değerlendirildiğini anlama ihtiyacı nedeniyle daha karmaşık olduğundan, yorumlamada ortaya çıkacak farklılıkları ortadan kaldırmak önemlidir. Bu nedenle Türkiye’de farklı paydaşların üzerinde anlaşmaya varacakları bir denetim kalitesi göstergeleri seti geliştirmek için etkileşime girmesi ve iş birliği yapması gerekli görülmektedir.
Analisa Pengaruh Strategi Pemasaran dimasa Pandemi COVID-19 Terhadap Penigkatan Kinerja UMKM Provinsi Aceh Dimoderasi Oleh Teknologi
Authors: Chalirafi Chalirafi , Matriadi Faisal , Munandar Munandar
Published: June 2023

Penelitian ini sangat penting untuk dilakukan dikarenakan perlu dilakukan penelitian yang mendalam dengan menggabungkan kajian teoritis dan lapangan mengenai faktor yang mempengaruhi terhadap kinerja pada UMKM untuk memaksimalkan kontribusinya dalam peningkatan potensi ekonomi. Tujuan khusus penelitian ini adalah untuk menguji dampak dari pendekatan pemasaran dimasa pandemi covid-19 terhadap kinerja UMKM dengan teknologi sebagai variabel moderator dengan subjek penelitian UMKM di Provinsi Aceh. Tahapan penelitian meliputi: observasi data, menentukan permasalahan pokok, tujuan kegiatan, studi literatur, pengunmpulan data, pengolahan data, analisa hasil, serta evaluasi hasil penelitian. Hasil penelitian diharapkan dapat menghasilkan asumsi dan pendapat yang dianggap signifikan terhadap pemasaran pada kinerja UMKM dimasa pandemi COVID-19 dengan teknologi variabel sebagai moderator.
The Analisys of The Green Economy Implementation on Sustainability Small and Medium Enterprise in lhokseumawe City
Authors: Biby Sapna , Asbar Yuli , Jufridar Jufridar
Published: June 2023

The amount of SMEâ€™s in Lhokseumawe city was 2058 that consist of different production sector, culinary, craft and other sector under the guidance of the Industrial agency, trade, union and Small Medium Enterprises in Lhokseumawe). The sustainability of MSMEs is a problem that needs attention from researchers considering that the existence of MSMEs is very important in supporting the community's economy. Sustainability is inseparable from various factors ranging from Green Input, Green Process, Green Output, and Green Marketing. The results of the study conclude that green input has a significant effect on entrepreneur knowledge, Green Input has no significant effect on MSME sustainability, Green Marketing has no significant effect on entrepreneur knowledge, Green Marketing has no significant effect on MSME sustainability, Green process has no significant effect on entrepreneur knowledge, Green the process has a significant effect on the sustainability of MSMEs, green products have a significant effect on the knowledge of entrepreneurs, green products have a significant effect on the sustainability of MSMEs, the knowledge of entrepreneurs has a significant effect on the sustainability of MSMEs, Green Input has an insignificant effect on the sustainability of MSMEs through entrepreneur knowledge, Green Marketing has a significant effect on MSME Sustainability through entrepreneur knowledge and green products have no significant effect on MSME sustainability through entrepreneur knowledge. Lhokseumawe City Government can disseminate and provide guidance to MSME entrepreneurs regarding sustainable business that found to have a weak performances. In addition, MSME entrepreneurs could increase the awareness of the environment side to side with the business activities.
Impactos Emocionais e Evangelização
Authors: Tepe Valfredo
Published: June 2023

“A verdade vos libertará” (Jo 8,32). O homem age em suas decisões e na sua conduta conforme a visão que tem do mundo, das coisas, das pessoas, em conformidade, pois, com a “sua verdade”, a sua maneira de ver e compreender. Uma visão intelectual destorcida ou parcial deturpa ou “escraviza” o comportamento. Um rapaz, p. ex., que olha o seu pai como um tirano, terá uma conduta de mêdo servil ou de revolta aberta ou incubada. Pouco adianta dizer-lhe sêcamente a verdade “objetiva” de ser seu pai tudo, menos um carrasco, ser êle, p. ex., um tipo extremamente escrupuloso na sua missão pedagógica. A verdade neste caso não liberta, não modifica a conduta, simplesmente pelo fato de não atingir realmente o indivíduo. E não chega a atingi-lo por causa de barreiras emocionais...
Por uma Igreja Interpenetrada com o Mundo
Authors: Kloppenburg Boaventura
Published: June 2023

“A Igreja está no Mundo, não é do Mundo, mas para o Mundo” (Paulo VI, 19-7-1967). Ela é e deve ser para todos e cada um o “sacramento universal de salvação” (LG 48b,129; GS 45a,342; AG 1c,862; 5a,875). Ela é missionária por natureza: natura sua missionaria est (AG 2a,865). E toda ela é missionária: tota Ecclesia missionaria est (AG 35,982). Não apenas tem uma missão: ela é missão. “Ide e fazei discípulos meus todos os povos, batizando-os em nome do Pai e do Filho e do Espírito Santo, ensinando-os a observar tudo quanto eu vos mandei” (Mt 28,18-20). Todos os povos! Todos...
Reflexões Bíblicas sobre alguns Aspectos da Palavra «Evangelho»
Authors: Mesters Carlos
Published: June 2023

O Pequeno Dicionário de língua portuguêsa traz cinco significados diferentes para a palavra evangelho na linguagem popular: 1. Doutrina de Cristo; 2. Cada um dos quatro livros principais do Novo Testamento; 3. Trechos dêstes livros que se lêem na celebração da Missa; 4. Coisa que se tem por verdadeira; 5. Conjunto de preceitos pelos quais se rege uma seita...
Antimutagenic effect of grape seed extracted oil on diazinon induced genotoxicity in albino mice
Authors: Al-Attar Mustafa S.
Published: June 2023

Background: Human health hazard due to exposure to chemical pollutants is a global and chronic problem. The pesticides constitute the primary toxic chemicals in the environment. The present study explored the effects of grape seed oil supplementation on diazinon (DZN) induced chromosomal aberrations and sperm abnormalities in male mice. Materials and methods: The tests were carried out on 35 adult male albino mice (16-20 weeks, weighed 30-35 g). Animals were categorized into seven groups each with five mice; the first group was treated with phos¬phate buffer saline (PBS) as negative control group. The second and third groups were treated daily and orally with two different doses of the DZN (60 and 90 mg/kg body weight) respectively dissolved in corn oil. Animals of fourth, fifth and sixth groups were orally administered grape seed oil at a dose of 2 g/kg body weight, after 6 hours the fourth and fifth groups subjected to DZN at the same dose given to second and third groups. Animals of the seventh group were supplied with corn oil. The treatments were continued for five weeks. Results: The results showed that DZN increased the frequency of both chromatid and chromosome aberrations in bone marrow cells and sperm abnormalities. Treatment with grape seed oil extract showed a significant decrease (P<0.01) on both total abnormal chromosomes and sperms, and there was no significant difference between these groups and negative control in most analyzed parameters. The dose of grape seed oil has significantly minimized the effect of first dose of DZN concerning chromosome structure while it worked in the second dose regarding sperm abnormalities. Conclusions: This finding suggests the protective action of grape seed oil against DZN induced clastogenecity and sperm abnormalities.
A cytogenetic study on workers in leather tanning industry
Authors: Ismail Noor H.
Published: June 2023

Peripheral blood samples were obtained from thirty three leather tannery workers directly involved in the tanning process in the tanning factory at Al- Zaafarniya / Baghdad , one of the factories of state company for leather tanning industries. In addition peripheral blood from twenty healthy control individuals (not known to be exposed to chemicals or other potentially genotoxic substances) were used as control group. The micronucleus (MN) assay was performed using the cytochalasin B technique. We observed a highly significant increase in the mean frequency of lymphocyte micronuclei (MN) and nucleoplasmic bridges (NPBs) , a significant increase in the mean frequency of nuclear buds (NBUDs) and a highly significant decrease in the mean frequency of nuclear division index (NDI) of the tannery workers group in comparison with the control group. The results of the present study also indicate the influence of service duration of tannery workers in lymphocyte MN , NPB, NBUD and NDI frequencies . The age of tannery workers also effect in lymphocyte micronuclei and nuclear division index frequency. The conclusion from our study that the tannery factory workers studied have experienced genotoxic exposure, which is manifested as an increase in the frequency of lymphocyte MN, NPB, NBUD and a decrease in NDI this work shows a clear genotoxic effect. Our study recommends providing all occupational safety requirements for workers in the factory and commitment of workers apply them.
The cytotoxic effect of Vincristine-Amygdalin combination on human cervical cancer cell line (Hela cancer cell line)
Authors: Jumaa Azal H.
Published: June 2023

Resistance of cancer cells toward chemotherapeutics drugs is considered as the major problem of cancer treatment. One of the strategies that are used to overcome cancer cells resistance to anticancer drugs is the drugs combination. Vincristine and amygdalin combination was used in this study to identify the possibility of synergistic effect between them as anticancer, which is mainly due to unrelated mechanism of action for vincristine and amygdalin. The result of the study demonstrate that the cytotoxic effect of (vincristine and amygdalin) combination was significantly more than the cytotoxicity of each one alone on Hela cancer cell line (human cervical cancer cell line). The result shows also the cytotoxicity of (vincristine and amygdalin) combination increases with the increase in the concentration which ranged between (1-10000) µg/ml, beside the increase in the incubation periods which are (24, 48 and 72) hours.
Ultrasound features and molecular diagnosis testing of thyroid mass
Authors: Ismael Nadhum J.
Published: June 2023

Thyroid gland is one of the most important glands in human body due to the necessary hormones it produces. It can be afffeced by different types of infections and diseases, one of the most risky abnormalities of this gland is thyroid masses. The aim of this study is to find how does thyroid masses start from the molecular stages and is there any relation with it and genetics, for this purpose we scanned more than 273 patients by ultrasound from different ages groups, and genders, thyroid mass detected in 17 of them, 3 with cystic fluid filled mass, and 14 with solid mass . Blood samples from thes patients were analysed and molecular study were performed by taking exon 11 and 15 from Braf gene mution was detected in all patients included frame shift mutaion a deletion of adenine in same position , while no sequence variation was found in the exon 11 Braf gene. In conclusion According to DNA sequence analysis, genomic variation was not found in exon 11 of the BRAF gene in all patients, an exonic alteration was detected in exon 15 in 7 patients was deletion of (A) in coding nucleotide , which the BRAF mutational hot spot region are found. The result of the deletion mutation is conversion of all of codons after deletion
Determination of DNA damage induced after bitter orange (Citrus aurantium) essential oil administrated in vivo
Authors: Saad Zaynab
Published: June 2023

This research was carried out in order to investigate whether the purified bitter orange (Citrus aurantium) volatile oil purified from peels has a potentiality to induced DNA damage if administrated orally in vivo. White adult male rats (180- 250g) were divided into five groups each group with five individuals. The first three groups administrated three different concentration of the purified citrus essential oil 100, 200 and 300µl/ kg Body weight (Bwt). The fourth group administrated olive oil and served as positive control group. The fifth was administrated water as negative control group. Dosing for all groups were two times weekly for one month period. To detected DNA damage, alkaline single cell gel electrophoresis (SCGE) for the blood samples was carried out for all groups. Parameters of nuclear olive moment, comet tail length, and DNA on comet tail were calculated. Results showed that there were no significant differences between treated and control untreated groups as well as olive oil administrated group. These results indicate that citrus volatile oil has no genotoxic effect and it was safe and tolerable in the highest dose used for the specified period of time conducted.
Development and Validation of RP-HPLC Method for the Determination of Anticancer Drug Brigatinib
Authors: Mossammat Rima Akter  , Md. Saddam Hossain  , K M Khairul Alam  , Md Rafiquzzaman
Published: June 2023

Now-a-days, one of the most devastating and life-threatening disorders is cancer. Various types of cancer based on the organ affected are namely lung cancer, breast cancer, stomach cancer, colon cancer etc. A number of anticancer drugs are obtainable among which tyrosine kinase inhibitor is the superior one. The available tyrosine kinase inhibitors are namely Crizotinib, Ibrutinib, Osimertinib, Brigatinib. Among them, brigatinib is the recent INN drug which belongs to second generation of tyrosine kinase inhibitor and indicated for non-small cell lung cancer. Literature review shows that there are no developed methods available for determination of brigatinib except UPLC method. In the present study, authors aimed to develop and validate RP-HPLC method for determination of brigatinib. Regarding RP-HPLC method, C18 column (ID: 5 micron*100 Å) was employed as stationary phase while combination of methanol and distilled water (75%:25%) was used as mobile phase. The retention time of brigatinib was found 5.6 min from the chromatogram. The regression equation was y = 53344x - 239.6 with coefficient of determination (R2) 0.999 and correlation coefficient (r) 0.9994; indicating excellent linearity of the calibration curve obtained by the newly developed method. Percent (%) RSD for robustness, ruggedness, precision was below 2. Limit of detection and limit of quantification were found to be 0.332 μg/mL and 1.00 μg/mL, respectively. The findings ensure the suitability of the developed method as an established one to assay brigatinib in any quality control laboratory.
An evaluation of outpatient pediatric asthma prescribing patterns in the United States
Authors: Lejla Cukovic  , Elizabeth Sutherland  , Sandi Sein  , Damaris Fuentes  , Huma Fatima  , Anwar Oshana  , Ateequr Rahman
Published: June 2023

Pediatric asthma is often under-diagnosed and under-treated, resulting in a lack of concentration, difficulty sleeping, and tiredness. The Global Initiative for Asthma (GINA) guidelines recommended that children should be prescribed maintenance inhalers along with rescue inhalers. Concurrent use of rescue and maintenance inhalers were considered appropriate use for this study. The aim of the study was to determine the prevalence of inappropriate prescribing patterns against various patient and prescriber demographic factors. A total of 2,264 patients meeting the inclusion criteria for ICD 10 codes, J45.20 - J45.52 and age less than 18 were extracted from the 2018 National Ambulatory Medical Care Survey (NAMCS), which captures ambulatory services offered in physicians’ offices directly engaged in patient care. This data is collected by the National Center of Health Statistics (NCHS), a division of the CDC. The data were analyzed using descriptive analysis, two-tailed t-tests, and ANOVA with an alpha significance level at 0.05. The majority of the pediatric patient population was in the age range of 17-18 years old. Overall, more patients were prescribed inappropriately (68.3%) as compared to appropriate prescribing (31.7%). Inappropriate prescribing was seen more for patients with Medicaid (24.8%) and self-payment (38.2%) as compared to other types of payment (p= 0.052). General practice/ family physicians (35.1%) and nurse practitioners (20.9%) prescribed more inappropriately as compared to other prescribers. (p= 0.001). Patients from the Southern region of the U.S. were prescribed more inappropriately compared to the other regions in the U.S. (p= 0.205). This study concluded that a significant number of pediatric asthma patients across all demographics were not appropriately prescribed inhalers, thus not adhering to GINA guidelines. Appropriate prescribing and adhering to guidelines would prevent morbidity, mortality and improve the patient's quality of life, thereby saving healthcare costs.
Prevalence and risk factors of hypertension among HIV patients: A retrospective cross sectional study of a Nigerian tertiary hospital
Authors: Suleiyol Charity Abatur  , Ugomma Loveth Anyaji  , Igba Richard Injor  , Daniel Friday Onuh
Published: June 2023

Background: Recent studies have linked HIV and antiretrovirals with cardiovascular conditions including hypertension (HTN). HIV/HTN comorbidity may not only worsen prognosis of the diseases but may pose the challenge of non-adherence due to increased pill burden and side effects. Objectives: This study seeks to determine the prevalence and risk factors of hypertension among HIV patients. Methods: The study was a retrospective cross-sectional research among 254 people living with HIV (PLWH) on antiretroviral therapy (ART) at the Federal Medical Centre (FMC), Makurdi, Benue State, Nigeria, who were seen by a physician between January and August 2022. A validated data collection sheet containing all required variables was used. Results: The prevalence of hypertension among the population of study was 15.4%. The final regression model showed that occupational status, educational level, and difference in CD4 count were not significant predictors. Increasing age (OR = 1.066; CI = 1.013 – 1.121; P = 0.014) and body mass index (BMI: OR = 1.274; CI = 1.149 – 1.413; P = 0.000) were seen to be associated with increased odds of developing hypertension. Conclusion: The prevalence of hypertension in this study population was high. Traditional risk variables (advanced aged and increased BMI) were independently, significantly associated with hypertension but neither CD4 count, viral load nor ART use were significantly associated with it. The findings support the development of guidelines for routine blood pressure monitoring for PLWH receiving ART.
A retrospective descriptive study on analyzing knowledge and attitudes of care towards prehospitalization care for Cerebrovascular accident patients.
Authors: Venkata Lakshmi Karri  , Sridevi Gudala  , Karunya Reddy Kunduru  , Chatterjee Partha Pratim  , Maryline Flinsi
Published: June 2023

A Cerebrovascular Accident (CVA) is a neurological disorder of the CNS and has a higher risk of death or a permanent neurological sequel. The incidents of cardiovascular and neurological disease are skyrocketing in developing countries like India. Despite many efforts by the government and many public health activists and experts, it is still higher and may lead to permanent damage to the social structure of the families of patients. A non-experimental retrospective descriptive research design was adapted to find out the knowledge of the primary caretaker/s towards the prehospitalization care of CVA patients at Apollo Hospitals, Kakinada. A total of 203 caretakers were identified. Out of that, 170 participated in the study, 23 were lost to follow-up, and 10 refused to participate in the study. Data was collected using a structural knowledge questionnaire. 20 questions were asked to the patient’s relatives for their responses to assess the frequency percentage of knowledge and attitude of caretakers regarding the care of CVA. The Data was analysed using descriptive and inferential statistics (including frequency count and percentage). The study findings revealed that 42.9% assumed that CVA is a bio-infection, and 51.1% believed that CVA primarily involves the heart. Regarding clinical presentation, 41.7% believe that CVA has sudden onset weakness, 40.5% believe that it has sudden onset headaches, and 42.9% are unable to identify that it has numbness in the hands. Finally, early identification and treatment are essential for every CVA patient to avoid devastating lifelong complications. Therefore, it is appropriate that the caretaker or close relative of the patient has knowledge enough to identify CVA.
Development of cardiac phantom which mimics the heart function using a 4.7t preclinical MRI system for cardiac imaging
Authors: Eze BE  , Ettah EB  , Ushie, PO  , Bassey AE  , Igomah GO
Published: June 2023

Cardiac MRI was one of the first MRI applications in the 1980s, which helps in the human study of different cardiovascular diseases. MRI is a noninvasive imaging technique that can be used for diagnosis and has advantages over other imaging techniques since it does not rely on radiation like X-rays, PET, and SPECT. Modern clinical methods do not require much scanning time, it revels good contrast between tissues and can compensate for patient movement during the scan. The scanner used is a 300mm internal diameter superconducting magnet (Magnex Uk) 4.7T preclinical MRI system, in the Biomedical Physics building at the University of Aberdeen. The cardiac phantom is made of a balloon filled with water, connected via a nylon T-piece to two 5 m lengths of rigid pvc tubing of 3 mm internal diameter to a 12 V water pump and solenoid valve located outside the 4.7 T MRI system’s 5 Gauss stray field contour. The balloon part of the phantom was fixed on the 4.7 T MRI system’s animal bed, directly over a 30mm diameter surface coil normally used to image the rat heart. The flow system was primed with water to mimic blood and the bed was loaded into the MRI magnet for imaging. The cardiac phantom has successfully been developed using a small balloon to represent a heart chamber and imaged in a 4.7T preclinical MRI scanner. Images acquired with gradient echo pulse sequence with shorter TE of 5 ms and using surface coil displayed improved image contrast and have useful signal-to-noise ratio as compared to images acquired with birdcage coil which show ghosting artifact.