bluuebunny/crossref_metadata_2025 huggingface dataset:
Mechanism of LDH and IL-8 involved in pancreatic cancer pain and the correlation of pain degree
Authors: Zhou Zhiming , Guo Zongfeng , Lu Xiaomin , Xu Xiaoqing
Published: April 2024

Background: This research aimed to observe the mechanism of lactate dehydrogenase (LDH) and interleukin 8 (IL8) in pancreatic cancer pain and their correlation with pain degree. Methods: 126 patients with pancreatic cancer who visited our hospital from January 2021 to February 2023 were selected. The patients were divided into groups of 58 patients with low pain (1~3 points) and 68 patients with high pain (4~10 points) by visual analog scale (VAS). And 50 health examinees in the same period were selected as the healthy control group. The serum LDH and IL-8 concentrations are analyzed by enzyme-linked immunosorbent assay, and the subjective pain grading method score is analyzed. The differences in LDH and IL-8 concentrations among the three groups of patients were compared. Pearson correlation analysis was used to investigate the correlation between LDH, IL-8 concentrations, and patient pain. Binary logistic regression was used to determine independent risk factors for high pain, and ROC curves were used to analyze the diagnostic efficacy of each indicator. Results: The serum LDH and IL-8 concentrations in the high-pain group were exceed the low-pain group's (P<0.05). The serum LDH and IL-8 concentrations in the low-pain group exceeded the healthy control group's (P<0.05). Pearson correlation analysis revealed a positive correlation between serum LDH concentration and pain grading (r=0.736, P=0.000). The serum IL-8 positively correlates with pain grading (r=0.680, P=0.000). Serum LDH and IL-8 concentrations positively correlate (r=0.589, P=0.000). LDH and IL-8 concentrations are independent risk factors for high pain levels (OR=1.033, 1.142, P<0.05). The logistic regression prediction model formula was used: Y=constant+B1X1+B2X2+...+BnXn to set the joint diagnostic prediction model as -12.063+ 0.033×LDH+0.133×IL-8. The areas under the ROC curves of LDH, IL-8, and predictive model (LDH+IL-8) in patients with high pain were 0.925, 0.945, and 0.974, respectively. The relevant standards for LDH are >190 U/L, IL-8 is >36 pg/mL, and the relevant standards for prediction models are >5.75. Conclusions: LDH and IL-8 participate in the pain aggravation process of pancreatic cancer and are closely related to the pain grading. The combination of LDH and IL-8 can be used as a biological indicator to evaluate the pain severity of pancreatic cancer and provide a reference for clinical diagnosis and treatment.
Techno-Pedagogical Competency among teachers in relation to their attitude towards teaching
Authors: Chauhan Deepika
Published: April 2024

The purpose of this study is to determine the Techno-Pedagogical Competency and attitude towards teaching of teachers from selected colleges in Gurgaon District. A normative survey method was adopted in this stage. A sample of 190 teachers were selected from various colleges. The study found that the level of Techno-Pedagogical Competency and the teachers’ possessed a favourable attitude towards teaching. Further, it was found that there exists a significant difference in Techno-Pedagogical Competency and attitude towards teaching mean score among teachers with respect to gender, locality, teaching experience, and type of institutions. Further, it can be revealed that there was a significant positive correlation between Techno-Pedagogical Competency and attitude towards teaching. Overall, this study provides valuable insights into the current state of Techno-Pedagogical Competency and attitude towards teaching among teachers in Gurgaon District. The findings suggest that the teachers in the region have a good grasp of using technology for pedagogical purposes and hold a positive outlook towards their teaching profession. The results also highlight the importance of considering demographic factors when analyzing teachers’ competency and attitude.
Terrorismo en la España Democrática
Authors: Avilés Farré Juan
Published: April 2024

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Ramón Lamoneda, un marxista revolucionario en la secretaría general del PSOE, 1936-42
Authors: Mateos Abdón
Published: April 2024

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Medicina mental y eugenesia: los fundamentos ideológicos de la psiquiatría franquista en la obra de Antonio Vallejo-Nágera
Authors: Campos Ricardo , Huerta Rafael
Published: April 2024

Nuestro principal objetivo es analizar la importancia de las relaciones entre eugenesia y psiquiatría en el pensamiento de Antonio Vallejo-Nágera. Pretendemos contextualizar sus propuestas científicas y políticas en el pensamiento general de las décadas de 1920-1930, y valorar cuáles son los elementos originales de su obra y cuáles son heredados. Asimismo intentaremos demostrar que su obra eugénesica forma parte de un proyecto biocrático destinado a superar el liberalismo y destruir la democracia.
Sangre, votos, manifestaciones: ETA y el nacionalismo vasco radical (1958-2011)
Authors: Fernández Soldevilla Gaizka , López Romo Raúl
Published: April 2024

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limitaciones de la transición española. El imposible retorno de los republicanos de ARDE, los casos de Victoria Kent y Francisco Giral
Authors: Hoyos Puente Jorge de
Published: April 2024

Este artículo aborda los problemas del retorno de los exiliados republicanos Victoria Kent y Francisco Giral desde una perspectiva crítica hacía las limitaciones de la Transición española. La imposibilidad de integración del movimiento republicano debilitó el relato democrático de todo el proceso.
Reseña de: José Manuel ROCA, La oxidada Transición, Madrid, La Linterna Sorda, 2013
Authors: Fernández Soldevilla Gaizka
Published: April 2024

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Transición en Galicia
Authors: Grandío Seoane Emilio
Published: April 2024

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Precisiones en torno a la memoria del exilio republicano en la etapa socialista. Respuesta a Mari Paz Balibrea, Historia del Presente, 23, 2014
Authors: Nieto Blanco Felipe
Published: April 2024

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Introducción
Authors: Soto Carmona Álvaro
Published: April 2024

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extensión de los seguros sociales en el mundo rural gallego: entre el clientelismo político y los ecos del ‘Estado de Bienestar’ (1940-1966)
Authors: Lanero Táboas Daniel
Published: April 2024

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Fenomenología como arqueonomía
Authors: Sanz Marco
Published: April 2024

Este trabajo esboza un programa de investigación que anuda la fenomenología del cuerpo con la paleontología humana y con la antropología filosófica, a fin de examinar si y en qué medida los vínculos existentes entre la experiencia corporal, la imaginación y la memoria pueden formalizarse en términos geométricos tales como la verticalidad y, en ese sentido, constituir una base para la determinación simbólica de fenómenos orgánicos.
WTIV on the Edge: What Happens when the Achieved Preload Reaction is Exceeded
Authors: Vazquez Jose H. , Strachan Frank D.M. , Foo Kok Seng
Published: April 2024

All jackups, such as those used as Wind Turbine Installation Vessels (“WTIVs”) must undergo a process known as preloading before elevating the hull to the operating airgap. This is done to ensure that the seabed on which they are installed is capable of supporting the unit during elevated operations. Ideally, the soil at the sites of WTIV operations would be uniform with ever-increasing capacity with leg penetration, but that is not the case all the time. Instead, some sites have soil profiles with weaker sub-layers below stronger upper layers, with a regression in the capacity of the sub-layers of soil. At some sites, the soil capacity decreases with increased leg penetration. These sites are commonly referred to as having “punch through potential.” Herein, these are also referred to as “difficult sites.”

If during the preload process at a difficult site, all legs penetrate completely through the regression section of the soil, the degree of confidence in the integrity of the foundation for all operations in the elevated condition is high. That is not the case if/when one or more of the legs do(es) not reach the predicted leg penetration and the achieved preload reaction is just below the local peak in soil capacity. This scenario creates a condition in which a slight increase in load (beyond the achieved preload reaction) can cause the leg to enter the soil regression zone during elevated operations.

While it is a given that operators must ensure that the leg reactions in the elevated condition never exceed the achieved preload reactions to avoid possible foundation failure, a thorough risk assessment demands that we ask the following question:

What would happen if/when, while performing crane operations on a 4-legged unit (after having properly completed preload operations) at a difficult site, for some unforeseen reason (poor weight control, more wind/current/wave load than expected or extending the crane boom more than originally planned), the reaction on a leg that stayed at the shallow penetration gets to be higher than the capacity of the soil at that penetration (thus entering the regression section of the soil)?

This paper seeks to answer that question, noting that if that were to happen on a 3-legged jackup, a leg run will certainly ensue, leading to a punch through event (“PTE”). But, is it possible that in that same situation, a 4-legged jackup only has minimal extra penetration on the overloaded leg and reaches equilibrium relatively quickly by virtue of load redistribution (from the overloaded leg to the other legs), never having a leg run or a PTE?
Causes du décrochage scolaire des filles dans la ville Province de Kinshasa, cas du district de la FUNA de 2010 à 2013.
Authors:   Université Pédagogique Nationale, BASILA BATITEYAU Bernadette
Published: April 2024

La présente étude a examiné le problème lié à l’éducation des filles avec un accent particulier sur les causes du décrochage scolaire. Divers aspects de la pauvreté des femmes stipulent que ces dernières sont fragilisées dans la société du fait qu’elles sont pauvres. L’éducation des filles facilitant l’intégration de la femme dans le processus du développement souffre du manque de scolarité des parents, base du phénomène désastreux de transfert intergénérationnel de la pauvreté. La présente étude focalisée sur le phénomène du décrochage scolaire des filles dans le milieu de Kinshasa indique que les principales raisons d’abandon scolaire sont : le manque de payement de frais scolaires (24%), ce qui s’accompagne avec la pauvreté des parents (12%), le découragement des élèves filles après l’échec à la première période et le manque d’encadrement (10%). Nos enquêtes ont aussi montré que les grossesses indésirables et le mariage précoce interviennent respectivement pour (7%) et (3%), les autres causes incluent la mauvaise appréciation des enseignants (6%), le changement d’adresse de la maison d’habitation (5%), le manque d’école disponible (4%), le divorce de parents (3%) et enfin les mauvaises conditions de santé et la malnutrition des élèves. Mots-clés : Décrochage scolaire, Élèves, Enseignants, Parents, Kinshasa, Pauvreté.
Évaluation de l’accessibilité en eau potable des habitants du quartier SAIO dans la commune de Ngiri-Ngiri.
Authors:   ISP Bandundu, KIMPEPE Aline
Published: April 2024

L’eau potable n’est pas accessible à tous de la même manière. Environ une personne sur quatre n’avait pas accès à l’eau potable gérée en toute sécurité à son domicile. C’est une étude descriptive et transversale sur l’évaluation de l’accessibilité en eau potable des habitants du quartier SAIO dans la commune de Ngiri-ngiri. La population cible est estimée à 8757 habitants. Nous avons recouru à l’échantillonnage non probabiliste de commodité qui nous a permis de prélever un échantillon de 150 habitants du quartier SAIO. Pour réaliser cette étude, nous avons recouru à la méthode d’enquête, les techniques documentaires, d’observation et d’interview nous ont permis de consulter les ouvrages et les articles de revue ayant trait au sujet de notre recherche, d’observer le milieu de recherche et d’entrer en contact avec nos enquêtés pour recueillir les informations à l’aide d’un questionnaire d’enquête électronique établies grâce à l’application KOBO collecte qui a analysé les données collectées. Nous avons trouvé dans notre étude que les chefs de ménages sont de sexe féminin soit 79%. La plupart sont dans la tranche d’âge comprise entre 22 et 31 ans soit 42% dont l’âge moyen vaut 29±10,77 ans. 62% n’ont pas un niveau d’études, 53,33% sont sans emploi, 60% de chefs de ménages ont une taille de ménages comprise entre 7 et 11 personnes, 50,7% vivent dans le quartier entre 1 à 9 ans. Nous avons trouvé que 62,7% de ménages ont un robinet dans la parcelle, 96,7% des ménages ont accès à l’eau 2 fois par semaine, 64,7% d’eau ont un aspect sale de couleur jaunâtre. L’eau de robinet est utilisée dans 96,7% pour la lessive. Les enquêtés ont accès à l’eau de robinet vers 03h soit 38%. 100% des enquêtés utilisent l’eau traitée et commercialisée comme breuvage. Le coût mensuel de l’eau de boisson est <10000fc par mois dans 88,7% de cas. 100% des enquêtés sont tombés malades pour avoir bu l’eau de robinet et 57,3% ont souffert de la diarrhée. Mots-clés : Eau potable, accessibilité, Ngiri-ngiri
ANALYSE ET IMPACT DE LA CONSTRUCTION D’UNE ROUTE EN TERRE BATTUE A BUMBA. Cas du tronçon allant du Rond-point Mobutu jusqu’à l’Avenue du fleuve.
Authors:   Institut Supérieur Pédagogique et Technique Bumba, NZENGO GBANGBA Eusèbe
Published: April 2024

Les voies de communication en général et les infrastructures routières en particulier sont des facteurs important et incontournable pour le développement économique, culturel et social d’un pays ou d’un continent. L’objectif de cette étude est d’analyser l’impact de la construction de ce tronçon en terre battue en relevant les différentes dégradations et en faisant ressortir une structure satisfaisante pour une bonne circulation des personnes et leurs biens. Le tronçon fait partie d’une route d’intérêt régional dans la cité de Bumba géré par l’Office des Voiries et Drainage (OVD) qui a une longueur de 1570 m. Le résultat obtenu lors de nos études menées pour la construction de la route du tronçon allant du Rond-point Mobutu jusqu’à l’Avenue du fleuve, est que la structure sera en chaussée de terre battue tout en tenant compte des aspects environnementaux. Nous avons enfin, pour maintenir l’état de route, construit des ouvrages d’assainissement et un ouvrage de franchissement pour protéger le talus. Mots clés : Impact, Construction, Route, Terre battue
European experience in organizing physical education and promoting a healthy lifestyle in educational institutions
Authors: Tsybanyuk Oleksandra , Slyvka Larysa , Batiuk Alim , Liasota Tatiana
Published: April 2024

In this article, the European experience of organizing physical education and promoting a healthy lifestyle in educational institutions is analyzed. The research aims to identify the main features of the concepts of physical education and sports that dominated Western Europe in the late twentieth and early twenty-first centuries. It is noted that the basic concepts of physical education and sports of the 1970s in certain countries have been transformed into more balanced ones. It is indicated that the main content of the Bologna declaration is that 47 member countries have committed themselves to bring their educational systems in line with a model that is transparent and easily comparable. This allows for the issuance of European-style diplomas over time. The analysis of the development of PE and sports in Western Europe allows us to draw some conclusions that may be useful for the leaders of various state authorities and sports organizations to improve the system of physical education and sports. Actions aimed at improving the physical fitness of young people, preserving and developing the need for physical activity, increasing the enrollment of students in sports clubs, and participating in competitions are of utmost importance, as they distract young people from various harmful hobbies typical of the academic sphere.
Analysis of job burnout in people working in sports in the universities of Baghdad
Authors: Nasser Ali Jamel , Hussein Alwan Qutaiba , Salman Dawood Mohannad
Published: April 2024

The objective of this research was to analyze job burnout in people working in sports in the universities of Baghdad. The researchers used the descriptive approach with survey method, and the sample was composed of 290 sports activity workers. The researchers defined the scale and procedures and applied them to the research sample. The data obtained were processed and interpreted to obtain conclusions. A high level of job burnout was found in the participants of this study. To solve this problem, the authors think that it would be recommendable that people working in sports in the universities of Baghdad are given the opportunity to develop their abilities and are involved in decision-making.
Report from the 2nd international workshop on FAIR containerized computational software
Authors: Hotaling Nathan
Published: April 2024

The National Institute of Standards and Technology (NIST) is evaluating and improving the specification for achieving interoperability of containerized computational software. Adherence to a specification for Findable, Accessible, Interoperable, and Reusable (FAIR) Containerized Computational Software (FAIR–CCS) enables better reuse of containerized tools in complex data analyses by chaining tools into computational workflows. NIST requested information from the community on approaches to achieving interoperability of containerized software, designing a container manifest file that meets the community needs, and lowering the barrier for constructing such a manifest file. Responses to this RFI informed a possible revision of the current approach to achieving FAIR–CCS via a manifest file, the entries in the current manifest file specification of FAIR–CCS, and the current tools that aim at automating adherence to the FAIR–CCS manifest specification.
Transformando la Educación Básica: Retos y Perspectivas de la Inteligencia Artificial
Authors: Cabrera Loayza Karelys Viviana
Published: April 2024

El estudio aborda los desafíos y perspectivas de la implementación de la Inteligencia Artificial (IA) en la Educación Básica con el objetivo de mejorar la calidad y equidad educativa. Se empleó un enfoque mixto en 14 instituciones educativas, con la participación de 69 docentes y 14 directivos. Utilizando encuestas, entrevistas y observaciones de clase, se recopilaron datos cuantitativos y cualitativos. Los resultados revelan tendencias divergentes entre género y edad en la adopción de la IA, con mayor familiarización entre las mujeres en niveles iniciales. Además, se identificó una distribución equitativa en la experiencia laboral entre géneros en ciertos rangos de tiempo. Se observa una preferencia por aplicaciones de IA relacionadas con la generación de contenido sobre análisis y detección. Estos hallazgos sugieren la necesidad de abordar desequilibrios de género y de promover un uso equilibrado de la IA en la educación básica para maximizar su potencial y mejorar la calidad educativa para todos los estudiantes.
The Effects of Monitoring and Evaluation on the Performance of Diary Community Processing Centre in Rwanda
Authors:   https://oaskpublishers.com/assets/article-pdf/the-effects-of-monitoring-and-evaluation-on-the-performance-of-diary-community-processing-centre-in-rwanda.pdf, Bosco Harelimana Jean , Umugwaneza Marthe
Published: April 2024

This research is interested in carrying out research on the effects of Monitoring and Evaluation on the Performance of Diary Community Processing Centre in Rwanda. In order to assess the relationship between Industrial development projects monitoring and evaluation for projects performance, an assessment conducted demonstrated that Monitoring is being done on monthly, Quarterly, semi-annually and annually and evaluation is done during baseline stage, mid-way of the project, End term of project and ex post of the project. The results showed that 67.9% were strongly agreed that the developed indicators were being monitored and evaluated regularly, 89.3% of them were also strongly agreed that the developed Performance indicators track project/program changes and provided the details information on the Performance of the program at Burera Diary Ltd while 75% of the reported that there is an appropriate way to monitor and evaluate the project/program progress made along its implementations. The result from interview guide for NIRDA staffs showed that RMMF and M&E manuals were most useful M&E tools used by NIRDA M&E team to monitor and evaluate Burera Diary Ltd projects. They highlighted the aggregates and disaggregates indicators to be monitored and evaluated include, number of new jobs created, changes in sales and productions, changes in technologies used, changes in profits, changes in exports and assess how these listed indicators shall impact the lives of communities. Finally, the beneficiaries responded that their lives improved and more changes happened in their families like most of them bought land, built the houses and pay the tuition fees of their children.
Strengthening Health Systems in Conflict: Evidence-Based Policies for Quality Care in Yemen
Authors:   Management Science, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra, India, Ali Alraimi Ammar , Shelke Abhijeet
Published: April 2024

Yemen’s health system has faced formidable obstacles due to the enduring conflict since 2014, resulting in compromised infrastructure, disrupted services, and exacerbated vulnerabilities. This discourse meticulously analyzes the primary health system challenges in Yemen within the framework of the World Health Organization’s six pillars. It subsequently presents evidence-based policy recommendations to enhance Yemen’s health system and ensure the provision of high-quality and equitable care. In terms of service delivery, it suggests augmenting the presence of community health workers, leveraging mobile health technology, rehabilitating facilities, and improving emergency obstetric care. Regarding the health workforce, it proposes financing mechanisms for adequate remuneration, task-shifting strategies, embracing telemedicine, and fostering partnerships with universities. To strengthen information systems, it advocates for the enhancement of facility reporting, the implementation of national surveys, the utilization of mobile phone surveys, and the adoption of robust health information software. Regarding essential medicines, it recommends reorganizing regulations pertaining to selection, procurement, storage, and distribution. For health financing, it highlights the importance of increasing domestic budget allocation, implementing user fee exemptions, adopting performance-based financing mechanisms, and strengthening financial management systems. Last, in terms of governance, it emphasizes the need for transparent and accountable leadership, effective coordination mechanisms, and inclusive policy-making processes. Yemen requires sustained political commitment and adequate resources to facilitate the comprehensive reconstruction of its health system.
Digital Story of Woman Character in Gilman’s The Yellow Wallpaper
Authors: Tenrisanna Rasynal , Rahman Fathu , Abbas Herawaty , Pattu Amir
Published: April 2024

This article aims to describe the performance of the woman character as shown in the story and to reveal the achievement of obsession that the woman has obtained in the story. The analysis of the work has been carried out by using structuralism and a psychoanalysis approach from Freud’s theory and collaborate with creative digital illustration can be helped the readers understanding the story on digital illustration. The result of this analysis shows that woman character may appear to hold a less powerful role in society throughout Gilman’s work. The Yellow wallpaper is locked in a room by her ‘loving’ spouse, as a physician. The story centers on her need for an escape as the kind of remedy that is needed to cure her illness. She expresses her desire for an escape and hides from her spouse. In creative digital illustration of the story concept can be appeared into plot stories. The woman character can be shown on illustration using graphic design.
Nuevas expresiones de organización empresarial. Revisiones para un análisis
Authors:   Universidad Autónoma de Guadalajara, Brito Cervantes Esmeralda , Magaña Moya Santos ,   Universidad Autónoma de Guadalajara, González Pérez Mario Guadalupe ,   Universidad Autónoma de Guadalajara, Rojas Altamirano Omar Guillermo ,   Universidad Panamericana
Published: April 2024

Esta colaboración buscó recopilar experiencias de vida cotidiana que tomadores de decisiones realizaron y realizan en su actividad empresarial para contribuir de manera puntual con una batería de alternativas, que si bien podrían no aplicar a casos específicos, sí podrían inspirar al diseño de nuevas opciones de intervención, y, sobre todo, hacia la disminución de incertidumbre en las decisiones sectoriales.
Change of erosive potential of apple and orange juice at different dilutions
Authors: Steiger-Ronay Valerie , Stelz Sebastian , Steigmeier David , Becker Klaus , Wiedemeier Daniel B , Attin Thomas
Published: April 2024

The aim of this in vitro study was to investigate the change of erosive properties of apple and orange juice after dilution with tap water. Apple juice, orange juice and citric acid were assessed for pH and titratable acidity at different aqueous dilutions (100% – pure liquid, 60% – 3 : 2 mixing ratio, and 40% – 2 : 3 mixing ratio respectively). Thus, 72 bovine enamel specimens were distributed to 9 groups (n = 8 specimens per group), followed by 25 minutes of erosion by superfusion with the described test liquids according to group allocation. Erosive substance loss (µm) was determined profilometrically. The different substance losses within a dilution series were tested using the Wilcoxon rank sum test. The significance level was set to p ≤ 0.05. Erosive substance loss [µm] for 100% concentrations (median ± interquartile range) was highest for apple juice (5.7 ± 0.8), followed by citric acid (4.6 ± 0.4) and orange juice (1.5 ± 0.5). The dilution of apple juice (60%: 4.2 ± 0.7; 40%: 3.1 ± 0.5) and citric acid (60%: 3.7 ± 0.9; 40%: 2.8 ± 0.7) with tap water lead to a significant (p < 0.05) reduction of erosive potential in comparison to 100% concentrations. This effect was not consistent for orange juice, where significantly more substance loss was found for pure juice (100%) than for 60% diluted juice (60%: 1.1 ± 0.3, p < 0.05), but no significant difference was found between 100% and 40% (40%: 0.9 ± 0.6, p > 0.05), and 60% and 40%, respectively. In conclusion, dilution of apple juice with tap water led to a significant reduction of its erosive potential. For orange juice, the effect of dilution on the erosive substance loss was only limited.
The comparison and processing of Electromyography (EMG) signals under different actions
Authors: Zhu Zhiyu , Jiao Tiankuo
Published: April 2024

The experiment first investigates the working principle and the applications of Electromyography (EMG). Then, the effect of electrode location and electrode size on the EMG signal is explored by the raw data and theory. The reasons for choosing generic surface Ag/AgCl adhesive electrodes are also described. After obtaining the raw EMG signals, suitable data processing methods, such as Root Mean Square (RMS) and digital filtering are applied to generate signals that can drive the motor of a prosthetic arm. The results obtained by the two methods are also compared, where RMS can provide larger peak and mean values, and the digital filtering method can minimise the phase shift. Finally, the limitations of the EMG for prostheses are also analysed by three aspects: different flexion forces, individual finger motion and different reference locations.
Research overview of Osmanthus fragrans beer
Authors: Zhang Zenghao , Cui Yunqian , Fu Yiting , Yin Zemiao
Published: April 2024

Osmanthus fragranced flowers, rich in a variety of beneficial components, is a good example of homology of medicine and food. Brewing beer with Osmanthus fragrans is not only enjoyable but also has health benefits. The article introduces the beneficial components and aromatic substances of Osmanthus fragrans, discusses the Osmanthus fragrans beer brewing process and the characteristic flavor components, in order to provide theoretical support and technical reference for the research and development of Osmanthus fragrans beer.
Metronidazole Refractory Giardiasis Complicating the Management of Rhabdomyosarcoma in a Child
Authors:   Department of Microbiology, National Cancer Institute, All India Institute of Medical Sciences, New Delhi, India, Khan Salman , Kharchandy H. Larikyrpang ,   Pasteur Institute, Shillong, Meghalaya, India, Kataria Babita ,   Department of Medical Oncology, National Cancer Institute, All India Institute of Medical Sciences, New Delhi, India
Published: April 2024

Giardiasis caused by Giardia duodenalis is one of the leading causes of gastroenteritis, especially in developing countries. The scenario may be further complicated by emerging metronidazole refractory cases worldwide. We present a case of a 2-year-old girl on chemotherapy for metastatic para meningeal rhabdomyosarcoma. She had a 15 day history of persistent diarrhea of foul-smelling loose stools, without fever. Light microscopy of stool wet mounts revealed cysts and trophozoites of Giardia duodenalis. The patient was managed with nitazoxanide after metronidazole proved ineffective clinically. This case highlights the importance of timely diagnosis and management of infectious diseases and rising antimicrobial resistance among parasites.
Heydar Aliyev on spiritual education of the young generation
Authors:   Mingəçevir Dövlət Universiteti, Yusubova Turkana
Published: April 2024

The article focuses on the protection of national traditions, inculcation of national and spiritual values, national consciousness, self-consciousness, national feelings and national character among the socio-psychological and socio-pedagogical problems of our republic, which has entered the path of indepedence at a time of rapid integration into European countries. Such issues take a main place with its urgency. In this regard, the protection of our national values and their transmission to future generations is even more important today. Because our national values reflect the identity of the Azerbaijani people.
Surgical Resection of Giant Chest Wall Chondrosarcoma Combined with Sandwich Chest Wall Reconstruction in One Case
Authors: Xu Peng , Yu Guangmao , Wang Haiyong , Jia Qiye , Ma Zhifeng
Published: April 2024

Introduction: Primary chest wall tumors account for 5% of all thoracic neoplasms and 1% of all primary tumors. Chondrosarcoma is a rare solid tumor, with an annual incidence of <0.5 per million people per year. It predominantly occurs in the pelvis and femur, occasionally occurs in flat bones such as the sternum and ribs, and rarely invades lung tissue. Chest wall chondrosarcomas represent only 5–15% of all chondrosarcomas. Radical surgery often leads to a large range of chest wall defects, especially when the range exceeds 6 cm × 6 cm and involves the sternum, spine, or multiple consecutive ribs. The reconstruction of the chest wall bone should be considered to restore the integrity and stability of the chest, prevent chest wall softening and abnormal breathing, and ensure the stability of respiratory circulation. Chest wall reconstruction can help restore thoracic hardness and integrity, prevent lung hernia and abnormal breathing, while also ensuring a positive aesthetic outcome. The chest wall reconstruction includes reconstruction of the pleura, bony structures, and soft tissues.
Case Report: In our case of an adult male, after the resection of the third and fourth anterior rib chondrosarcoma, the common anatomical plate was shaped and fixed to the stump of the third rib with screws to ensure the stability of the thorax while retaining the mobility of the thorax. After applying hernia mesh pruning, the chest wall defect was stitched to complete the pleural reconstruction of the defect area. This procedure can effectively maintain the stability of the pleural cavity, provide more effective support for the chest wall soft tissue, and promote the recovery of upper limb function and lung function.
 Conclusion: The radical surgery of giant chest wall chondrosarcoma often leads to a large range of chest wall defects. Chest wall reconstruction needs to be carried out at the same time to restore the integrity and stability of the chest wall, to avoid chest wall softening and abnormal breathing, and to ensure the stability of respiratory circulation. Using the “sandwich” method for chest wall reconstruction, in which an anatomical plate is combined with hernia mesh and muscle soft tissue, and during which pleura, bony structure, and soft tissues are reconstructed, can provide more effective support for chest wall soft tissue, effectively prevent postoperative muscle tissue collapse, avoid postoperative abnormal breathing, and promote the recovery of postoperative upper limb function and lung function. It is a very effective method for chest wall reconstruction.
Postoperative Bowel Obstruction as a Rare Complication of an Abdominal Drain
Authors: Perysinakis Iraklis , Vassalou Evangelia E. , Saridakis Georgios , Triantafyllou Matthaios , Christodoulou Vasilis , Triantafylla Paraskevi , Papadaki Eufrosini , De Bree Eelco
Published: April 2024

Although routine intra-abdominal drain insertion following surgery represents a  common practice worldwide, its utility has been questioned during the last  decades. Several comparative studies have failed to document significant benefits  from routine draining, and drain insertion has been correlated with various complications as well. Drain-related complications include, but are not limited,  to infection, bleeding, and tissue erosion. Herein, we present the case of a 32-year-old patient with perforated peptic ulcer and purulent peritonitis, whose postoperative course was complicated by early mechanical bowel obstruction due to an abdominal drain. A high level of clinical suspicion, along with accurate imaging diagnosis, dictated prompt removal of the drain, which resulted in immediate resolution of the patient's symptoms. We aim to increase the clinical awareness of this rare complication related to intra-abdominal drain utilization  with this report.
The Relationship of Microsatellite Instability with BRAF and p53 Mutations and Histopathological Parameters in Colorectal Adenocarcinoma
Authors: Gündoğar Özgecan , Bektaş Sibel , Yıldırım Emine , Gönüllü Doğan
Published: April 2024

Aim: This study aims to elucidate the associations between microsatellite instability (MSI) status, BRAF mutation, and p53 reactions with pathological parameters and survival outcomes in colorectal carcinoma. 
Material and Method: MutL homologous 1 (MLH1), Postmeiotic segregation increased 2 (PMS2), MutS homologous 2 (MSH2), MutS homologous 6 (MSH6), BRAF, and p53 antibodies were performed on 130 adenocarcinoma samples, including 65 from the right colon and 65 from the left colon. The relationships of MSI status with BRAF mutation, p53 reaction, clinical and pathological parameters, and survival times were statistically analyzed. 
Results: A statistically significant relationship was found between MSI and right colon localization, tumor size, histological grade, intraepithelial tumor-infiltrating lymphocytes, Crohn-like lymphocytic reaction, expansive growth pattern, and BRAF mutation (p < 0.05). No significant correlation was found between MSI status and the disease-free or overall survival times (p > 0.05). 
Conclusion: In colorectal adenocarcinoma, MSI and BRAF mutation are associated with parameters, indicating the host immune response and prognostic histopathological parameters, including tumor size and histological grade. The evaluation of MSI status and BRAF mutation can be particularly informative for predicting the prognosis and guiding the treatment management in poorly differentiated colorectal adenocarcinoma. Understanding the mechanisms of molecular carcinogenesis in colorectal carcinoma and organizing treatment algorithms based on molecular foundations will increase the success of the treatment.
Treatment Options and the Management of Complications in Hydatid Cysts of the Liver in Endemic Regions
Authors: Daduk Yildiray , Seker Ahmet , Sozutek Alper , Olmez Tolga , Kaplan Kuntay , Dur Huseyin , Ozdemir Gorkem
Published: April 2024

Background: Hydatid cyst of the liver induced by Echinococcus granulosus is a pervasive zoonotic disease in our region. Its incidence varies across age groups, contingent on community lifespans and hygiene standards. Therapeutic modalities include Puncture, Aspiration, Injection, Re-aspiration (PAIR), and surgery. Due the limited feasability of PAIR, we suggest that surgery represents the optimal treatment in all stages, especially in endemic regions, depending on patient-specific variables.   
Method: Patients with hydatid cyst of the liver treated with PAIR and surgery in our center between January 2016 and January 2022 were analyzed retrospectively. PAIR or cystectomy were applied in treatment. These were then compared in terms of efficacy, feasibility, and complications.   
Results: A single hydatid cyst of the liver was detected in 184 of the 225 cases, two cysts in 33, and three or more cysts in eight. The largest cyst diameter was 233 × 124 mm in the surgery group and 100 × 90 mm in the PAIR group. One hundred thirty-three of the 225 patients underwent open surgery, and no recurrence was encountered in these. However, recurrence was observed 19 patients treated with PAIR. Allergic reaction developed in one case during surgery, postoperative abscess in two cases, biliary fistula in five, and pneumonia in one.   
Conclusion: Surgical treatment should represent the standard procedure since it is safe and effective, ensures complete elimination of the parasite, involves no intraoperative shedding, preserves healthy tissues, and minimizes the risk of long-term recurrence and cavity-related complications.
Value of Aesthetic Designs in Two Coffee Shops in Metro Manila: Inputs for New Business Developers
Authors:   Asian Institute of Maritime Studies, Obenza Blezelda , Buenaventura Rhio ,   Asian Institute of Maritime Studies
Published: April 2024

Coffee shops have become one of today’s go-to places for people of all ages making it as meeting venues, places to relax, and even alternative study spots. Consequently, coffee shops have placed importance on their aesthetic design as part of their business strategy to attract customers. Researchers conducted a study to gather evidence on the value of aesthetic design in coffee shops in Metro Manila. Specifically, this study aimed to determine if there is a difference in the value of aesthetic design between various coffee shops and if respondents differ in their aesthetic perception based on their demographic profiles. Using researcher-made survey questionnaires, data was collected from 100 coffee shop goers. Results showed that both male and female respondents appreciate the aesthetic designs of coffee shops. It was also revealed that majority of coffee shop goers are students and have valued mostly the atmosphere and ambiance of coffee shops. Likewise, the aroma of the coffee stimulates them. Data showed that there is no significant difference in the value of aesthetic design in terms of gender (p < 0.98), age (p < 0.23), and social status (p < 0.06). However, there is a significant difference in the value of aesthetic design in terms of frequency of visits to coffee shops (p > 0.045). The researchers suggest, especially to new business developers, that the aesthetic design of coffee shops must be highlighted as it significantly impacts consumer behavior. This, in turn, can increase patronage and foster greater connection with consumers.
FINANCIAL INCLUSION: BRIDGING THE GAP FOR SUSTAINABLE DEVELOPMENT.
Authors: Patil Roopali , Patil Rohit
Published: April 2024

This paper examines role of financial inclusion for sustainable development. Financial inclusion has emerged as a critical driver for economic growth and poverty mitigation worldwide. This research paper explores the multifaceted dimensions of financial inclusion, aiming to understand its importance, challenges, and potential impact on sustainable development. The study explores into the various strategies, technologies, and policies employed globally to enhance financial inclusion, with a focus on both developed and developing economies. Financial inclusion stands at the forefront of sustainable development, serving as a catalyst for economic growth, poverty alleviation, and social progress. This research paper delves into the multifaceted role of financial inclusion in fostering sustainable development. By examining the existing challenges, exploring innovative solutions, and assessing the broader implications, the paper aims to provide insights into how bridging the financial inclusion gap can contribute to a more sustainable and equitable future.
EXAMINING THE RELATIONSHIP BETWEEN EMPLOYEE COMMITMENT ON ORGANIZATIONAL EFFECTIVENESS.
Authors: Kamule Rahul Arun , Patil Dr. S. C.
Published: April 2024

In the era of globalization, the concept of employee commitment is widely discussed within organizations. Research indicates that employee engagement not only enhances organizational effectiveness but also contributes to sustaining higher levels of commitment among employees. The extent to which an employee is devoted to their organization and its values is commonly referred to as employee commitment. Both employee productivity and allegiance to the company are pivotal factors in the overall success of the corporation. This essay aims to explore the significance of motivated employees in the ability of an organization to thrive and prosper. Specifically, the focus is on investigating the factors influencing the degree of commitment among employees at West Coast Paper Mills Limited, Dandeli. The data, derived from the responses of the organization's employees, undergoes evaluation and interpretation. Chi-square analysis and percentage analysis are employed for hypothesis testing. The study's findings inform the development of conclusions and recommendations based on the analyzed data, shedding light on the variables affecting employee commitment in the specified context.
PERSONNEL ENGAGEMENT AND RETENTION IN ORGANIZATIONS: A REVIEW OF LITERATURE.
Authors: Behera Smruti Rekha
Published: April 2024

Employee engagement and retention are vital considerations for organizations seeking to build a motivated and committed workforce that contributes to overall success. This literature review aims to provide a comprehensive analysis of the conceptual frameworks, key determinants, and effective strategies associated with personnel engagement and retention in organizations. By synthesizing existing research, this study offers a deep understanding of the factors that influence personnel engagement and retention, highlights successful strategies, and identifies avenues for future research. The review employs a systematic approach, encompassing an extensive search of scholarly articles, books, and relevant publications. The literature search focuses on studies investigating personnel engagement and retention, examining theoretical perspectives and empirical evidence. Through the extraction and analysis of key themes and findings, common patterns, factors, and strategies associated with personnel engagement and retention are identified. The review emphasizes the multidimensional nature of personnel engagement, incorporating emotional, cognitive, and behavioural aspects. Various theoretical frameworks, such as the Job Demands-Resources model, the Social Exchange Theory, and the Self Determination Theory, have been utilized to understand the antecedents and outcomes of personnel engagement. Factors such as job satisfaction, organizational culture, leadership styles, career development opportunities, and work-life balance emerge as significant determinants of personnel engagement. Furthermore, the review identifies effective strategies that organizations can employ to foster personnel engagement and enhance retention. Organizations that prioritize personnel engagement and retention are more likely to experience higher job satisfaction, improved productivity, and reduced turnover rates. While the literature emphasizes the importance of personnel engagement and retention, it also reveals gaps and areas for future research. Practical implications stemming from this review underscore the significance of adopting a holistic approach to personnel engagement and retention. Employee engagement initiatives should be integrated into talent management strategies, with an emphasis on continuous feedback, coaching, and mentoring.
Palimpsestes africains. Primitivisme et avant-gardes (Paris, 1901-1924)
Authors: Denogent Jehanne
Published: April 2024

Alors que le primitivisme est devenu un chapitre incontournable des manuels d’histoire de l’art, l’intérêt des écrivains d’avant-garde pour les cultures extra-occidentales a longtemps passé inaperçu. Ce livre s’attache à éclairer un faisceau de pratiques et de réflexions que les avant-gardes historiques ont associées aux cultures africaines dans les années 1901-1924. Le premier quart du XXe siècle est marqué en effet par la diffusion d’une culture coloniale en Europe, qui touche les écrivains autant que les artistes. De Guillaume Apollinaire à Tristan Tzara, en passant par Blaise Cendrars, Jean Cocteau ou Yvan Goll, nombreuses sont les avant-gardes à s’intéresser aux arts dits « nègres ». Aucune ne s’est rendue toutefois sur le continent africain. L’Afrique, dans leurs écrits, est une construction textuelle, fabriquée à partir de sources multiples. Cette enquête dégage les différentes strates de représentations convoquées puis transformées dans ce processus de resémantisation, et met en lumière la teneur discursive du primitivisme qui élabore une Afrique palimpseste. Par un examen historique précis et critique, elle révèle la présence d’un moment africain des avant-gardes littéraires francophones.