bluuebunny/crossref_metadata_2025 huggingface dataset:
Distribution of RV- and transiting exoplanets by masses and orbital periods taking into account observational selection
Authors: Ananyeva Vladislava , Tavrov Alexander , Korablev Oleg , Bertaux Jean-Loup
Published: July 2021

More than 95% of the known exoplanets were discovered by the transit- and radial velocity techniques. However, the observed distributions of planets by their masses and by their orbital periods are significantly distorted by numerous observational selections, different for these techniques and different surveys.We found and studied the de-biased statistical distributions of exoplanets by masses and by orbital periods for three groups of exoplanets: I. transiting planets discovered by Kepler ST, whose masses were measured by the follow-up radial velocity technique, II. transiting planets discovered by ground-based surveys (SuperWASP, HATNet, NGTS, XO, KELT, etc.), III. planets discovered by the radial velocity technique. The synthetic projective-mass distribution of RV planets obeys the piecewise power law with the breakpoints at ~0.14MJ and ~1.7MJ. The distribution of RV-planets with m = (0.011-0.087)MJ (or (3.5-28)ME) accurately obeys the power law with an exponent of -2, dN/dm ∝ m^-2. The distribution of RV planets with m = (0.21-1.7)MJ follows the power law with an exponent ranging from -0.7 to -0.8, dN/dm ∝ m^(-0.7…-0.8). The distribution of RV planets with m = (1.7-13)MJ is fitted by a power law with an exponent ranging from -1.7 to -2.0, dN/dm ∝ m^(-1.7…-2.0). In general, the synthetic projective-mass distribution of RV planets well agrees with the predictions of the population synthesis theory (Mordasini, 2018) and includes more detailed features to be discussed.The exoplanets distribution by periods generally follows a power law with an exponent of -0.75 and indicates a predominant (averaged) structuring of the planetary systems.De-biased mass distribution of RV-planets with orbital periods of 2-58 days is well consistent with a similar distribution of the Kepler planets. The mass distribution of the transit exoplanets detected by ground-based surveys is consistent with the similar distribution of RV planets with periods of 1-20 days.
Exploring the Nu2 Lupi system with CHEOPS
Authors: Delrez Laetitia ,   CHEOPS Consortium
Published: July 2021

***Results under embargo. Paper accepted for publication at Nature Astronomy, to be published in June.***Multi-transiting planetary systems around bright stars offer unique windows to comparative exoplanetology. Nu2 Lupi (HD 136352) is a naked-eye (V=5.8) Sun-like star that was discovered to host three low-mass planets with orbital periods of 11.6, 27.6, and 107.6 days via radial velocity monitoring with the HARPS spectrograph. The two inner planets (b and c) were recently found to transit by the TESS mission, prompting us to follow up the system with ESA's brand-new CHaracterizing ExOPlanets Satellite (CHEOPS). This led to the exciting discovery that the outer planet d is also transiting. With its bright Sun-like star, long period, and mild irradiation (∼5.7 times the irradiation of Earth), Nu2 Lupi d unlocks a completely new region in the parameter space of exoplanets amenable to detailed characterization. By combining all available space and ground-based data, we measured its radius and mass to be 2.56±0.09 REarth and 8.82±0.94 MEarth, respectively, and refined the properties of all three planets: planet b likely has a rocky mostly dry composition, while planets c and d seem to have retained small hydrogen-helium envelopes and a possibly large water fraction. This diversity of planetary compositions makes the Nu2 Lupi system an excellent laboratory for testing formation and evolution models of low-mass planets.
Circulation of energetic ions within Ganymede’s magnetosphere: a Monte-Carlo simulation approach
Authors: Plainaki Christina , Massetti Stefano , Jia Xianzhe , Mura Alessandro , Milillo Anna , Grassi Davide , Filacchione Gianrico
Published: July 2021

The study of Ganymede, the only known moon in the Solar System to possess an intrinsic magnetic field embedded within a planetary magnetosphere, is of significant importance in view of future missions to the Jovian system. Indeed, the dynamics of the entry and circulation inside Ganymede’s magnetosphere of the Jovian energetic ions, as well as the morphology of their precipitation on the moon’s surface determine the variability of the sputtered-water release and exosphere generation. The so-called planetary space weather conditions around Ganymede can also have a long-term impact on the weathering history of its icy surface.In this talk, I will discuss some key characteristics of the circulation of the Jovian magnetospheric ions within the environment of Ganymede as derived from the application of a single-particle Monte Carlo model driven by the electromagnetic fields from a global MHD model. In particular, the Jovian energetic ion circulation and precipitation to Ganymede’ s surface was estimated for different relative configurations between the moon’s magnetic field and Jupiter’s plasma sheet, characterized by conditions similar to those encountered during the NASA Galileo G2, G8, and G28 flybys of Ganymede (i.e., when the moon was above, inside, and below the center of Jupiter’ s plasma sheet). The resulting differences between the various surface precipitation patterns and the implications in the water sputtering rate will be discussed. The results of this preliminary analysis are relevant to ESA’ s JUICE mission and in particular to the planning of future observation strategies for studying Ganymede’ s environment.
Europlanet 2024 RI - Global Collaboration and Integration Development, NA1-T4: Strategic Plan 2020–2024
Authors: Cavalazzi Barbara , Heward Anita , Marcheselli Valentina , Mason Nigel
Published: July 2021

Since its foundation in 2005, Europlanet has sought to reach out and engage with planetary scientists across the globe. Today, Europlanet has a global role to connect the international planetary community through the common aim of working together to explore and understand our Solar System and exoplanetary systems beyond. It is therefore both timely and necessary to put in place a framework for a community-led roadmap for global collaboration as part of Europlanet’s future development as both a Research Infrastructure and as a Society.The Strategic Plan for Europlanet 2024 Research Infrastructure’s Global Collaboration and Integration Development that represents the outcome of a dedicated effort to define how to expand and intensify the new relationship between Europlanet and African, but also between Europlanet and North and South American and Asian collaborators, will be presented.
Atmospheric Rivers in CMIP5 climate ensembles downscaled with a high resolution regional climate model
Authors: Gröger Matthias , Dieterich Christian , Dutheil Cyril , Meier Markus , Sein Dmitry
Published: July 2021

Abstract. Atmospheric rivers (AR) are important drivers of heavy precipitation events in western and central Europe and often associated with intense floods. So far, the ARs response to climate change in Europe has been investigated by global climate models within the CMIP5 framework. However, their spatial resolution between 1 and 3° is too coarse for an adequate assessment of local to regional precipitation patterns. Using a regional climate model with 0.22° resolution we downscale an ensemble of 24 global climate simulations following the greenhouse gas scenarios RCP2.6, RCP4.5, RCP8.5. The performance of the model was tested against ER-I reanalysis data. The downscaled simulation notably better represents small-scale spatial characteristics which is most obvious over the terrain of the Iberian Peninsula where the AR induced precipitation pattern clearly reflect eat-west striking topographical elements resulting in zonal bands of high and low AR impact. Over central Europe the model simulates a less far propagation of ARs toward eastern Europe compared to ERA-I but a higher share of AR forced heavy precipitation events especially Norway where 60 % of annual precipitation maxima are related to ARs. We find ARs more frequent and more intense in a future warmer climate especially in the higher emission scenarios whereas the changes are mostly mitigated under the assumption of RCP2.6. They also propagate further inland to eastern Europe in a warmer climate. In the high emission scenario RCP8.5 AR induced precipitation rates increase between 20 and 40 % in western central Europe while mean precipitation rates increase by maximal 12 %. Over the Iberian Peninsula AR induced precipitation rates slightly decrease around −6 % but mean rates decrease around −15 %. The result of these changes is an overall increased contribution of ARs to heavy precipitation with greatest impact over Iberia (15–30 %). Over Norway average AR precipitation rates decline between −5 to −30 %. These reductions most likely the originate from regional dynamical changes. In fact, over Norway we find ARs originating from > 60° N are reduced by up to 20 % while those originating south of 45° N are increased. Also, no clear climate change signal is seen for AR related heavy precipitation and annual maximum precipitation over Norway where the uncertainty of the ensemble is quite large.
Turbulence dissipation rate estimated from lidar observations during the LAPSE-RATE field campaign
Authors: Sanchez Gomez Miguel , Lundquist Julie K. , Klein Petra M. , Bell Tyler M.
Published: July 2021

Abstract. The International Society for Atmospheric Research using
Remotely-piloted Aircraft (ISARRA) hosted a flight week in July 2018 to
demonstrate unmanned aircraft systems' (UASs) capabilities in sampling the
atmospheric boundary layer. This week-long experiment was called the Lower
Atmospheric Profiling Studies at Elevation – a Remotely-piloted Aircraft
Team Experiment (LAPSE-RATE) field campaign. Numerous remotely piloted
aircraft and ground-based instruments were deployed with the objective of
capturing meso- and microscale phenomena in the atmospheric boundary layer.
The University of Oklahoma deployed one Halo Streamline lidar, and the
University of Colorado Boulder deployed two WindCube lidars. In this paper,
we use data collected from these Doppler lidars to estimate turbulence
dissipation rate throughout the campaign. We observe large temporal
variability of turbulence dissipation close to the surface with the WindCube
lidars that is not detected by the Halo Streamline. However, the Halo lidar
enables estimating dissipation rate within the whole boundary layer, where a
diurnal variability emerges. We also find a higher correspondence in
turbulence dissipation between the WindCube lidars, which are not
co-located, compared to the Halo and WindCube lidar that are co-located,
suggesting a significant influence of measurement volume on the retrieved
values of dissipation rate. This dataset has been submitted to Zenodo
(Sanchez Gomez and Lundquist, 2020) for free and is
openly accessible (https://doi.org/10.5281/zenodo.4399967).
Development of a moving point source model for shipping emission dispersion modeling in EPISODE–CityChem v1.3
Authors: Pan Kang , Lim Mei Qi , Kraft Markus , Mastorakos Epaminondas
Published: July 2021

Abstract. This paper demonstrates the development of a moving point source (MPS) model for simulating the atmospheric dispersion of pollutants emitted from ships under movement. The new model is integrated into the chemistry transport model EPISODE–CityChem v1.3. In the new model, ship parameters, especially speed and direction, are included to simulate the instantaneous ship positions and then the emission dispersion at different simulation time. The model was first applied to shipping emission dispersion modeling under simplified conditions, and the instantaneous and hourly averaged emission concentrations predicted by the MPS model and the commonly used line source (LS) and fixed point source (FPS) models were compared. The instantaneous calculations were quite different due to the different ways to treat the moving emission sources by different models. However, for the hourly averaged concentrations, the differences became smaller, especially for a large number of ships. The new model was applied to a real configuration from the seas around Singapore that included hundreds of ships, and their dispersion was simulated over a period of a few hours. The simulated results were compared to measured values at different locations, and it was found that reasonable emission concentrations were predicted by the moving point source model.
Large-scale sea ice motion from Sentinel-1 and the RADARSAT Constellation Mission
Authors: Howell Stephen E. L. , Brady Mike , Komarov Alexander S.
Published: July 2021

Abstract. As Arctic sea ice extent continues to decline, remote sensing observations are becoming even more vital for the monitoring and understanding of sea ice. Recently, the sea ice community has entered a new era of synthetic aperture radar (SAR) satellites operating at C-band with the launch of Sentinel-1A in 2014, Sentinel-1B in 2016 and the RADARSAT Constellation Mission (RCM) in 2019. These missions represent 5 spaceborne SAR sensors, that together routinely cover the pan-Arctic sea ice domain. Here, we utilized over 60,000 SAR images from Sentinel-1AB (S1) and RCM to generate large-scale sea ice motion (SIM) estimates over the pan-Arctic domain from March to December, 2020. On average, 4.5 million SIM vectors from S1 and RCM were automatically detected per week for 2020 and when combined (S1+RCM) they facilitated the generation of 7-day, 25 km SIM products across the pan-Arctic domain. S1+RCM SIM provided more coverage in Hudson Bay, Davis Strait, Beaufort Sea, Bering Sea, and over the North Pole compared to SIM from S1 alone. S1+RCM SIM was able to be resolved within the narrow channels and inlets across the pan-Arctic alleviating the main limitation of coarser resolution sensors. S1+RCM SIM provided larger ice speeds with a mean difference (MD) of 1.3 km/day compared to the National Snow and Ice Data Center (NSIDC) SIM product and a MD of 0.76 km/day compared to Ocean and Sea Ice-Satellite Application Facility (OSI-SAF) SIM product. S1+RCM was also able to better resolve SIM in the marginal ice zone compared to the NSIDC and OSA-SAF SIM products. Overall, our results demonstrate that combining SIM from multiple spaceborne SAR satellites allows for large-scale SIM to be routinely generated across the pan-Arctic domain.
THE INERTIA OF THE REVOLUTION OR JUST THE BEGINNING: G. MORRIS ON THE FRENCH REVOLUTION OF THE XVIII CENTURY
Authors: Romanenko Daria Andreevna
Published: July 2021

The diary of G. Morris is valuable on the history of the French Revolution of the XVIII century, in particular on the problems of salon life in France, biographies of some outstanding personalities (Talleyrand, Lafayette, Necker). The article mainly focuses on the interpretation of events by the author of the diary — G. Morris, a revolutionary, politician, orator and a recognized authority in the circle of the upper class. G. Morris not only gives a chronology of the history of the revolution, but also rethinks this experience, which has become the subject for the study of this article. To reveal the topic, a question was raised, to which G. Morris indirectly gives an answer. The inertia of the revolution or just the beginning? Will there be a continuation of the revolutionary events or will it come to naught? And Morris was largely right when he said that the revolution did not achieve what was originally planned – freedom, which means that its work is not finished, but on the other hand, although the tension did not completely disappear, it was smoothed out by the activities of the government.
ANALYSIS OF MORBIDITY OF CHILD POPULATION OF ASTRAKHAN
Authors: Umarova D.N. , Pogrebnichenko E.R.
Published: July 2021

One of the indicators of population health is morbidity. In recent years, there has been a steady increase in the incidence rate of children in the Russian Federation, an increase in chronic and concomitant diseases, an increase in the number of disabled children. The article presents indicators of the level and structure of the incidence of children. The analysis of incidence rates allows us to say that in 2019. the first place is occupied by diseases of the digestive system, the second place is taken by the nervous system and the third place is taken by the musculoskeletal system.
DQN-BASED TRAFFIC SIGNAL CONTROL SYSTEMS
Authors: Kondratov Ivan Vladimirovich
Published: July 2021

Real-time adaptive traffic control is an important problem in modern world. Historically, various optimization methods have been used to build adaptive traffic signal control systems. Recently, reinforcement learning has been advanced, and various papers showed efficiency of Deep-Q-Learning (DQN) in solving traffic control problems and providing real-time adaptive control for traffic, decreasing traffic pressure and lowering average travel time for drivers. In this paper we consider the problem of traffic signal control, present the basics of reinforcement learning and review the latest results in this area.
A RETROSPECTIVE OF THE DYNAMICS OF THE LEGAL SYSTEMS OF THE IBERIAN PENINSULA
Authors: Lobanova Olga Nikolaevna
Published: July 2021

The Kingdom of Spain is a multi-ethnic state, which includes too many ethnic and cultural groups. In this regard, the issues of legal regulation of public relations between the ethnic regions of the State play a primary role in maintaining stability and unity. Thus, the study of the prerequisites and the process of development of the legal system in the Iberian Peninsula region have a high degree of significance.
Clinical outcomes and predictors of response for adalimumab in patients with moderately to severely active ulcerative colitis: a KASID prospective multicenter cohort study
Authors: Shin Seung Yong , Park Soo Jung , Kim Young , Im Jong Pil , Kim Hyo Jong , Lee Kang-Moon , Kim Ji Won , Jung Sung-Ae , Lee Jun , Kang Sang-Bum , Shin Sung Jae , Kim Eun Sun , Kim You Sun , Kim Tae Oh , Kim Hyun-Soo , Park Dong Il , Kim Hyung Kil , Kim Eun Soo , Kim Young-Ho , Kim Do Hyun , Teng Dennis , Kim Jong-Hwa , Kim Wonyong , Choi Chang Hwan ,   on behalf of the IBD Research Group of the Korean Association for the Study of Intestinal Diseases
Published: July 2021

Background/Aims: This study assessed the efficacy and safety of adalimumab (ADA) and explored predictors of response in Korean patients with ulcerative colitis (UC).Methods: A prospective, observational, multicenter study was conducted over 56 weeks in adult patients with moderately to severely active UC who received ADA. Clinical response, remission, and mucosal healing were assessed using the Mayo score.Results: A total of 146 patients were enrolled from 17 academic hospitals. Clinical response rates were 52.1% and 37.7% and clinical remission rates were 24.0% and 22.0% at weeks 8 and 56, respectively. Mucosal healing rates were 39.0% and 30.1% at weeks 8 and 56, respectively. Prior use of anti-tumor necrosis factor-α (anti-TNF-α) did not affect clinical and endoscopic responses. The ADA drug level was significantly higher in patients with better outcomes at week 8 (P<0.05). In patients with lower endoscopic activity, higher body mass index, and higher serum albumin levels at baseline, the clinical response rate was higher at week 8. In patients with lower Mayo scores and C-reactive protein levels, clinical responses, and mucosal healing at week 8, the clinical response rate was higher at week 56. Serious adverse drug reactions were identified in 2.8% of patients.Conclusions: ADA is effective and safe for induction and maintenance in Korean patients with UC, regardless of prior anti-TNF-α therapy. The ADA drug level is associated with the efficacy of induction therapy. Patients with better short-term outcomes were predictive of those with an improved long-term response.
Desafíos de la iniciación al tenis en Brasil
Authors: Corrêa Cortela Caio , Ginciene Guy , Milistetd Michel , Pinheiro de Souza Silvio , Abaide Balbinotti Carlos Adelar
Published: July 2021

El éxito de la iniciación al tenis se presenta como un punto determinante para la expansión y el mantenimiento del número de niñosinvolucrados en la práctica del deporte. Para asegurar el éxito, es imprescindible que los programas sean estructurados de la formacorrecta para crear un ambiente de práctica positivo, y también que los entrenadores involucrados son cualificados y conscientesde su trabajo con niños. Los programas bien organizados ofrecen puntos de acceso de calidad y trayectorias para la práctica detenis continuada, y efectivamente contribuyen al crecimiento y desarrollo del tenis en general.
Evaluation of Self-Directed Learning Readiness among Undergraduate Students in an Indian Physical Therapy Institute
Authors: Walankar Prachita , Panhale Vrushali
Published: July 2021

Self-directed learning (SDL) is an essential element in medical education to foster lifelong learning. Self-directed learning readiness is the extent to which an individual has the attitude, ability, skill and personality characteristics essential for SDL. This study aimed to analyze self-directed learning readiness among physiotherapy students. A cross-sectional study was conducted among 288 undergraduate physiotherapy students using Self-Rating Scale of Self-Directed Learning (SRSSDL) to assess self-directed learning readiness. Data were analyzed using the Statistical Package for the Social Sciences software version 21. Statistical significance was set at P<0.05. A total 288 participants, 143(49.65%) were in preclinical phase and 145 (50.35%) in clinical phase. Out of 288 physiotherapy students, 60.76% students had moderate level, followed by 37.5% with high level and 1.74% with low level of SDL readiness. The total SRSSDL score was higher in clinical students as compared to preclinical students using independent t test (p=0.000). Also, subscale scores of SRSSDL, awareness (p=0.000), learning strategies (p=0.000), learning activities (p=0.000), evaluation (p=0.000) and interpersonal skills (p=0.04) were higher in clinical students as compared to preclinical students using independent t test. The study showed that physiotherapy students had moderate level of SDL readiness. The SDL readiness was found to be higher in clinical students as compared to preclinical. It will assist the medical educators to incorporate more active learning strategies to enhance SDL skills and help in curriculum development.

Keywords: Self-directed learning, physical therapists, medical education, students.
Smoking Trends: A Cross Sectional Study in Dengkil, Sepang, Selangor, Malaysia
Authors: Williams Aniston , Az-Zahrah Amir Siti Fatimah , Zulhelmi Muhammad
Published: July 2021

It is estimated that more than 27,200 of Malaysians’ deaths annually are related to smoking. Majority of the smokers start smoking at the early age, smoke more than 15 years and spend less than RM 100 for cigarettes in a month. So, this study aims to determine the trend of smoking among smokers in a residential area in Dengkil, Sepang, Selangor.
A cross-sectional study was conducted among Malaysian, aged more than 18-year-old with a combination of stratified, systematic and simple random sampling. Respondents who fulfill the inclusion & exclusion criteria were interviewed using a validated questionnaire and data were analysed using SPSS.
The prevalence of current smoker was 23.5% with higher among male (50.7%), single (31.0%) and self-employed (44.1%). Peer pressure plays important role in either to start or to quit from smoking.
It is important to increase awareness program primarily in educational institutions such as schools and colleges.

Keywords: smoking, trend, prevalence, sub-urban, Selangor, Malaysian.
Anaesthetic Management of a Patient with Necrotizing Fasciitis: A Case Report
Authors: Chaudhary Shallu , Atwal Major Amit
Published: July 2021

Necrotizing fasciitis is a highly lethal bacterial infection of subcutaneous tissue and fascia. 77 year old male patient, smoker with necrotizing fasciitis underwent surgery:- left shoulder disarticulation in emergency OT under general anesthesia. Intraoperatively, the patient went into severe sepsis and developed arrythmias and hypotension which was managed with anti-arrythmic drugs and infusion norepinephrine. The patient responded to the treatment and the surgery was completed. Postoperatively mechanical ventilation was continued and subsequently the patient improved and was extubated 3 days later.

Keywords: Necrotizing fasciitis, necrotizing acute soft tissue injury, NASTI.
Generalized Joint Hypermobility: A Review
Authors: Ganu Sneha S , Tadge Aishwarya B
Published: July 2021

Generalized Joint Hypermobility (GJH) is a condition where most of an individual’s synovial joints are found to have a range of motion (ROM) beyond their normal limits. Like most human traits, joint hypermobility is multifactorial resulting from a combination of environmental factors (eg. age, trauma, injury, conditioning, infection, inflammation) and multiple genetic factors, each contributing a small amount to the total phenotype. Clinical features of JHS are mainly associated to the connective tissue and can either be articular or extra-articular. The Beighton 9-point scoring system – also referred to as the modified or revised Beighton score – is a widely accepted method used to define GJH. Management of Generalized Joint Hypermobility is multidisciplinary which requires a team of physicians, physiotherapists, occupational therapists and podiatrists, among others. Physical therapy rehabilitation comprising of core stabilizing, joint stabilizing, strengthening and proprioception enhancing exercise coupled with general fitness program form the basis of GJH management.

Keywords: Generalized Joint Hypermobility, Beighton Score, Joint Hypermobility.
Google Books Ngram Viewer
Authors: Shparberg Anna L.
Published: July 2021

The Google Books Ngram Viewer is a data mining tool that searches datasets derived from Google Books to generate frequency charts of language usage from the dawn of print until the present time. The available languages are English, French, German, Hebrew, Italian, Spanish, Chinese,
and Russian. With a database in excess of two trillion words, it is the largest corpus of linguistics information in existence. In spite of concerns about the reliability of metadata used in Ngram Viewer, it is still viewed as a valuable resource for research into long-term cultural trends.
IBISWorld
Authors: Silver Breezy
Published: July 2021

IBISWorld provides industry or market reports for a wide variety of industries in both consumer and manufacturing and include some more niche industries. Most of the reports are for the US, but they also have content for other countries including Canada, Mexico, UK, China, and more.
The database also has some content and tools that would help entrepreneurs and companies. There are many options for modules that institutions can subscribe, but the heart of the database is the US industry reports. The reports cover what is occurring in an industry, projections for the industry
outlook, and details on what it is like for businesses in the industry. The interface or search options could use some improvements, but it is a relatively easy database to use especially with the large search box. The resource contains some great content that anyone doing marketing research
and entrepreneurs would find it helpful.
Library and Information Science Source
Authors: Luke Stephanie
Published: July 2021

EBSCO's Library and Information Science Source (LISS) is a subscription database that was developed from the merger of EBSCO and H.W. Wilson in 2011. LISS features journals, periodicals, conference proceedings, monographs, and book reviews in the field of library and information studies.
It includes full-text access to over 180 journals in both English and other languages. It also provides extensive indexing, a comprehensive thesaurus, and coverage from as early as the 1930s. The database's lack of OA content is at odds with library science's increasing commitment to freely
accessible content. LISS will be of the most interest to institutions with large library staff as well as those that offer a degree program in library and information studies.
Dimensions
Authors: Duffy Jane C.
Published: July 2021

Dimensions is a combined analytical, search & discovery, and information management database which has developed API tools to control and organize its holdings. The Digital Science philosophy has been that metrics and indicators belong to the scholars generating the research, not
to a vendor, hence the majority of its articles and bibliographic indicators are Open Access, and free to the research community. Charges are assessed, however, for Dimensions Plus subscriptions which provide links among policy papers, grant information, clinical trials, and other information
of interest to academic administrators, institutions, publishers, and librarians. Dimensions offers the ability to generate new knowledge: its data may be used, and a new information artefact created, without having to leave its platform. Featuring a full text index that enables deep discovery
and machine-learning based research classification, the search and navigation experience is smooth and intuitive. Offering many additional features that set it aside from traditional bibliometric databases, Dimensions is a tool that is designed primarily for expert users with knowledge of
the various facets and research processes of the disciplines in which they search information.
Effect of Sorafenib on Sex Hormone Levels in Male Swiss Albino Mice
Authors: Shetty Surekha D. , Bairy K. Laxminarayana , Prasad AM , Nayak B. Satheesha , Aithal P. Ashwini
Published: July 2021

Background: Hormones play a vital role in initiating and maintenance of male reproductive or testicular function which includes the production of androgens and spermatozoa. Testosterone is essential for the initiation and maintenance of spermatogenesis. FSH is responsible for the stimulation of spermatogenesis. Semen analysis and hormone evaluation are essential parameters in the diagnosis of infertility in males. Objective: The aim of the present study is to evaluate the effect of sorafenib on FSH and intratesticular testosterone levels in male Swiss albino mice. Materials and Methods: The animals were segregated into control, positive control, and treatment groups (n=6). Treatment group received 25, 50 and 100 mg/kg body weight of sorafenib orally for seven consecutive days at intervals of 24 hours between two administrations. Positive control group received 100 mg/kg body weight of imatinib. The animals were sacrificed at the end of 1st, 2nd, 4th, 5th, 7th and 10th week after the last exposure to sorafenib. Results: The intratesticular testosterone level was significantly (P<0.05) reduced in treated groups and severe effect was observed on week 4th and 5th weeks. FSH level was increased significantly (P<0.05) in sorafenib treated groups of mice. Conclusion: The administration of sorafenib does affect testosterone and FSH level significantly, but this effect is reversible once the drug is withdrawn. This finding may help the clinicians to plan and address the fertility-related issues in young patients of reproductive age who are being treated with sorafenib for advanced renal cell carcinoma, hepatocellular carcinoma and differentiated thyroid carcinoma.
Update on the role of Angiogenesis in Diabetes associated Nephropathy
Authors: Kakkar Munish , Singh Shreeja , Behl Tapan , Singh Sukhbir , Sharma Neelam , Hema Hema , Sachdeva Monika
Published: July 2021

Diabetic mellitus is common worldwide health problem which brings about different rigorous complications like retinopathy, nephropathy and numerous other lethal complications. Diabetic nephropathy is the major cause for blindness and renal failure in many of the developing countries. Hyperglycemia induced diabetic nephropathy gets elicited through improved development of reactive oxygen species in multiple cell types. The starting of organ damage or kidney failure shows some symptomatic effect or morphological changes as in one or both the kidneys like expansion or enlargement of kidneys from their original size and this enlargement process is known as nephromegaly. Microalbuminuria is the best possible predictable condition proceeding towards renal failure. This review briefly discussed about the diabetic nephropathy with regard to progression, angiogenic and non-angiogenic factors involved in pathogenesis and treatment of angiogenesis in diabetic nephropathy.
Smartphone Application for Diabetes in Indonesia: A Narrative Review
Authors: Maiisyah Perdani Adnin , Ikawati Zullies , Zainal Zainol Akbar
Published: July 2021

In 2017, Indonesia was ranked sixth in the top ten countries with the highest diabetes cases. The prevalence is expected to continue increasing. The use of Smartphone applications is one of the alternative methods in promoting better disease management and preventing diabetes. The purpose of this review is to identify existing studies regarding Smartphone applications for diabetes in Indonesia and to highlight the important findings. There are only a few original clinical studies about Smartphone applications for diabetes in Indonesia. A total of 5 studies were reviewed here. There are the Nutri Diabetic Care, the Teman DM, the DM Calendar App, the E-diary DM, and the Salam Sehat. The study was conducted on several respondents with the use of short-term applications and using the variable method. Nevertheless, the studies found that Smartphone applications for diabetes can be beneficial for improving self-care, self-efficacy, increased knowledge, and medication and diet compliance among diabetic patients in Indonesia. The information and utility criteria for diabetes application which should be relevant to clinical guidelines are not discussed. The implementation of Smartphone applications for diabetes is suitable for Indonesian condition. The best application with the right information, utility, and supported by clinical studies is suggested as a complement to the diabetes management by a health professional.
A Review on Floating Multi-particulate Drug Delivery System
Authors: B. Pund Suraj , C. Bhagat Vishwas , T. Deshmukh Madhuri , P. Kardile Deepak , V. Shete Rajkumar
Published: July 2021

The objective of writing this review on Floating Drug Delivery Systems (FDDS) was to accumulate new work with a special focus on the primary floatation mechanism for gastric retention. Drug delivery systems are those that instantly float on contact with gastric fluids and present promising approaches to improve the bioavailability of drugs with absorption windows in the stomach or upper small intestine, imbalanced in the intestinal or colonic environment, and exhibit low solubility at high pH standards. It is a novel drug delivery system that takes full advantage of effectiveness and compliance. Physical problems such as short gastric residence time and unpredictable gastric emptying time were overcome with the use of floating dosage forms that provide the possibility of local and systemic effects. The floating drug delivery system allows prolonged and continuous entry of the drug into the upper part of the gastric retention pathway and increases the bioavailability of the medication characterized by a narrow absorption window. This review provides detailed information on the pharmaceutical basis of its Introduction, Advantages, Disadvantages, Factors Affecting Gastric Emptying, and Criteria for Suitable Drug Products for Floating Gastric-Retention, Classification of Floating Multiparticulate Drug Delivery System, and Characterization of Floating Multiparticulate Drug Delivery System. These systems are beneficial for various difficulties encountered during the development of a pharmaceutical dosage form and the future potential of FDDS. This review article has attempted to announce to readers about the floating drug delivery system.
Chromatographic Fingerprint: A Modern Scientific Tool for Standardization of Traditional Medicines
Authors: Shukla Shiv Shankar , Sharma Vikash , Gidwani Beena , Vyas Amber , Daharwal S.J. , Kumar Pandey Ravindra
Published: July 2021

Drugs of natural origin play a significant role in the public health care system of any nation. Quality control is a challenging task for natural remedies. Natural products are different from traditional medicines and should be assessed for the quality. Chromatographic fingerprint produces a chromatogram that represents the chemical characteristics of herbal medicines. This strategy can serve as the proper monitoring of the quality and safety of medicinal herbs. Chromatographic fingerprint enables the characterization of complex herbal product with multi-constituents on a systematic manner with a quantitative degree of reliability. Fingerprint of herbal products through chromatographic techniques has been widely acceptable for evaluation of quality.
Pontine and extra-pontine osmotic demyelination syndrome: Case report
Authors:   Department of Neurology, Rua Dr. CesÃ¡rio Mota Jr, 112, Ed. Conde de Lara, 3rd floor, Vila Buarque, SÃ £ o Paulo-SP, Brazil., Santos Sousa Eduardo dos , Cabral Felipe Teijeiro ,   Department of Neurology, Rua Dr. CesÃ¡rio Mota Jr, 112, Ed. Conde de Lara, 3rd floor, Vila Buarque, SÃ £ o Paulo-SP, Brazil., Higa Lee Annelise Akemi ,   Department of Neurology, Rua Dr. CesÃ¡rio Mota Jr, 112, Ed. Conde de Lara, 3rd floor, Vila Buarque, SÃ £ o Paulo-SP, Brazil., de Oliveira Francisco Tomaz Meneses ,   Department of Neurology, Rua Dr. CesÃ¡rio Mota Jr, 112, Ed. Conde de Lara, 3rd floor, Vila Buarque, SÃ £ o Paulo-SP, Brazil., Gagliardi Rubens José ,   Department of Neurology, Rua Dr. CesÃ¡rio Mota Jr, 112, Ed. Conde de Lara, 3rd floor, Vila Buarque, SÃ £ o Paulo-SP, Brazil.
Published: July 2021

Osmotic demyelination syndrome is a rare disease, clinically presented as a global reduction in strength, tetraparesis, variations in the level of consciousness, and its content, and comatose status, associated with rapid variances in serum sodium levels (whether hyponatremia or hypernatremia). The neuroimaging findings are mainly in the pontine region, but currently the number of reports of extrapontine involvement has increased, typically with lesions in the topography of the thalamus, cerebellum, midbrain (substantia nigra), corpus callosum and hypothalamus. We display a rare case of pontine and extra-pontine involvement, even after the sodium replacement protocols of the current guidelines.
PENERAPAN PENDIDIKAN KARAKTER PADA ANAK USIA DINI SEBAGAI UPAYA PERUBAHAN PENDIDIKAN DI KELOMPOK BERMAIN MUTIARA BUNDA KABUPATEN CILACAP
Authors: Lathifah Inayatul , Azizah Wida Nurul
Published: July 2021

Pendidikan Karakter merupakan suatu upaya yang dapat dilakukan oleh lingkungan tempat tinggal untuk dapat memberikan bekal nilai-nilai kebaikan pada diri seseorang, sehingga mampu menjadi watak yang dibawanya sampai dewasa. Sejak kecil, Pendidikan karakter ini sudah dapat dikenalkan, dicontohkan, dan ditanamkan kepada anak melalui proses pembiasaan. Dari adanya penanaman nilai-nilai karakter dalam pembiasaan dan teladan inilah yang diharapkan dapat menjadi suatu upaya perubahan pendidikan yang dapat mulai diberikan sejak anak berada di jenjang Pendidikan Anak Usia Dini (PAUD) sebagai bekal memasuki ke jenjang pendidikan selanjutnya. Tujuan penelitian ini adalah untuk mengetahui penerapan pendidikan karakter pada anak usia dini bagai upaya perubahan Pendidikan yang diselenggarakan oleh Kelompok Bermain (KB) Mutiara Bunda Cilacap. Penelitian ini menggunakan pedekatan kualitatif jenis deskriptif. Metode yang digunakan yaitu observasi pembelajaran dan wawancara kepada kepala sekolah serta guru di KB Mutiara Bunda.Hasil dari penelitian ini adalah bahwa upaya penerapan pendidikan karakter yang dilakukan oleh KB Mutiara Bunda Cilacap secara garis besar dilakukan melalui pendidikan karakter dalam kurikulum dan kegiatan parenting. PAUD KB Mutiara Bunda Cilacap sejak pembuatan KTSP (Kurikulum Tingkat Satuan Pendidikan) sudah mencantumkan adanya Pendidikan karakter. Pada pembuatan dokumen Rencana Pelaksanaan Pembelajaran Harian (RPPH), guru sudah mencantumkan nilai-nilai karakter apa yang akan distimulasi kepada anak. Selain direncakan dalam kurikulum dan diimplementasikan dalam pembelajaran setiap hari di sekolah, pendidikan karakter yang diterapkan oleh KB Mutiara Bunda Cilacap ini juga diteruskan dengan penyampaian pentingnya pendidikan karakter kepada orantua anak.
SISTEM AUGMENTED REALITY (AR) DALAM DAKWAH ISLAM
Authors: Zein Mochamad T. A. Aziz , Agustin Ninik
Published: July 2021

The Use Of Mobile Technology In The Industrial 4.0 Era Is A Must. The Number Of Smartphone Users Continues To Increase Over Time. Contiinum Reality Technology Which Consists Of Both Virtual Reality (VR) And Augmented Reality (AR) Becomes A Portable Technology That Is Easy And Affordable Being Used With A Smartphone. This Study Has An Objective To Determine The Potential Uses Of Augmented Reality (AR) Technology In Modern Islamic Da'wa. This Study Are Counted As A Literature Study Using The Traditional Review Method.AR Applications Have Been Used In Many Fields, Such As Medical, Military, Manufacturing, Visualization, Entertainment And Games, Robotics, Education, Marketing, Navigation, Tourism, Geospatial, Urban Planning And Civil Sciences. Da’wa Requires Attention In Both Truth And Good Ability Of The Preachers. It’s Based On Legal Aspects And The Procedures (Fiqhud-Dakwah). There Was Limited Amount Of Research And AR Products Used In Da'wa. The AR’s Technology That Can Be Applied In Islamic Da'wa Are 1) Playing Cards For Da’wa, 2) Islamic Story Books, 3) Da’wa Brochures / Leaflets / Poster, 4) Islamic History Museum.
LIVING QURAN: RESEPSI AL-QUR’AN DI PONDOK PESANTREN AL-HUSNA DESA SIDOREJO PAMOTAN REMBANG
Authors: Huda Nur , Albadriyah Athiyyatus Sa’adah
Published: July 2021

This study aims to analyze the al-Qur'an reception at Al-Husna Islamic Boarding School Sidorejo Pamotan Rembang. This research is a qualitative research using inductive descriptive method. Qualitative research is a research procedure that analyzes descriptive data in the form of speech or written observations. Inductive descriptive method aims to describe and analyze data to obtain a general description or description of the al-Qu'ran reception at Al-Husna Islamic Boarding School. This research confirms that the Qur'an is a holy book that is always in harmony with all situations and conditions (ṣāliḥ li kulli zamān wa makān). The theory used by the researcher here is Karl Mannheim's sociological theory of meaning, which focuses on three typologies of meaning, namely objective, expressive, and documentary meanings. This study yielded at least two findings. First, there were several types of receptions at the Al-Husna Islamic Boarding School. Second, the meanings inherent in the reception include, a) objective meaning, that the variety of reception behavior at Al-Husna Islamic Boarding School is part of a symbol of obedience and disbelief towards the pondok regulations, b) the meaning of expression is manifested in the form of self-internalization with values positive values in the continuous learning process of the Koran, and c) documentary meaning is manifested in the form of local contextualization of a comprehensive cultural system.
STUDI ISLAM DALAM KACA MATA NORMATIF DAN HISTORIS
Authors: ‘Adzim Muhammad Fauzil , Vrikati Nela Syarah
Published: July 2021

Artikel ini ingin membahas bagaimana Islam dikaji dari kacamata keilmuan bukan dari sisi kayikinan. Islam dikaji dari segi pengetahuan menggunakan ilmu yang sering kita sebut sebagai Islamic Studies. Islamic studies ini sebagai pisau analisa dalam memahami Islam dari sisi pengetahuan bukan dari sisi keyakinan. Dalam islamic studies ini juga ada beberapa cara pandang dalam memahami Islam di anataranya ada segi normatif dan segi historis. Normatif ini adalah acara pandang sarjana muslim dalam mengkaji Islam dari segi teks, yang mana teks ini (al-Quran dan Sunnah) untuk memantapakan keyakinan mereka terhadap Islam itu sendiri. Untuk menguatkan segi nash (teks) maka diperlukan sisi historis dalam mengkaji Islam. historis menjadi penting dalam mengkaji Islam karena menguatkan, dan memantapkan eksistensi Islam itu sendiri dalam kancah ilmu pengetahuan.
Distributed moving horizon state estimation for sensor networks with low computation capabilities
Authors: Venturino Antonello , Stoica Maniu Cristina , Bertrand Sylvain , Alamo Teodoro , Camacho Eduardo F.
Published: July 2021

This paper focuses on distributed state estimation for sensor network observing a discrete-time linear system. The provided solution is based on a Distributed Moving Horizon Estimation (DMHE) algorithm considering a pre-estimating Luenberger observer in the formulation of the local problem solved by each sensor. This leads to reduce the computation load, while preserving the accuracy of the estimation. Moreover, observability properties of local sensors are used for tuning the weights related to consensus information fusion built on a rank-based condition, in order to improve the convergence of the estimation error. Results obtained by Monte Carlo simulations are provided to compare the performance with existing approaches, in terms of accuracy of the estimations and computation time.
Application Study of Newton-Raphson-Type Nonlinear MPC for Hydrostatic Transmissions Under Disturbance and System Uncertainty
Authors: Dang Ngoc Danh
Published: July 2021

Model predictive control is well established and has a huge practical relevance in many industrial applications, especially for chemical or thermal plants. This paper presents the design and the implementation of a nonlinear model predictive control aiming at an accurate tracking control of desired output trajectories under disturbances and uncertainties for a nonlinear hydrostatic transmission system with multiple control inputs, which represents a fast mechatronic system. The benefit of this solution is that it can be easily adapted to either velocity tracking control or torque tracking control -- which is not the case with alternative model-based approaches. The control design is based on a numerical optimization within a moving horizon using the Newton-Raphson method in combination with the optimization-over-some variables technique. The unmeasurable system state variables as well as the system disturbances are reconstructed by an unscented Kalman filter which is well suited for nonlineaer systems subject to process and measurement noise. The proposed control scheme is investigated by simulations and experimentally validated on a test rig at the Chair of Mechatronics, University of Rostock. The results indicates the robustness of the proposed control structure by a high tracking accuracy despite system disturbances and uncertainties.
Iconos. Historia gráfica y analítica de Colombia en su paso por los mundiales de futbol
Authors: Briñez Luisa , Vargas Henry
Published: July 2021

Este artículo realizó un análisis de los productos gráficos de los mundiales futbolísticos en relación con la selección Colombia. Se tuvo en cuenta diferentes puntos claves para su estudio como lo son la relación cromática, la composición y forma, encontrando el estilo de arte que utilizó, la forma de la tipografía, imágenes, fotografía e ilustraciones (Vega, 2017). Lo anterior fue encontrado en la elaboración de los posters, el logo y la mascota de cada mundial. Con esto se evidenció la evolución y el éxito obtenido con la publicidad y diseño de los mundiales de Chile 1962, Italia 1990, Estados unidos 1994, Francia 1998, Brasil 2014 y Rusia 2018. Con esta información recolectada se realizó una serie de infografías a manera coleccionable. En las infografías se puede encontrar datos curiosos de deportes y una descripción detallada del arte gráfico expresado en cada mundial.