bluuebunny/crossref_metadata_2025 huggingface dataset:
Serum vascular endothelial growth factor and cortisol expression to predict prognosis of patients with hypertensive cerebral hemorrhage
Authors: Zhang Chao-Yong , Wang Bin , Hua Xiang-Ting , Fan Kui , Li Yu-Feng
Published: August 2023

Hepatocellular carcinoma (HCC) is one of the most prevalent tumors worldwide and the leading contributor to cancer-related deaths. The progression and metastasis of HCC are closely associated with altered mitochondrial metabolism, including mitochondrial stress response. Mitokines, soluble proteins produced and secreted in response to mitochondrial stress, play an essential immunomodulatory role. Immunotherapy has emerged as a crucial treatment option for HCC. However, a positive response to therapy is typically dependent on the interaction of tumor cells with immune regulation within the tumor microenvironment. Therefore, exploring the specific immunomodulatory mechanisms of mitokines in HCC is essential for improving the efficacy of immunotherapy. This study provides a comprehensive overview of the association between HCC and the immune microenvironment and highlights recent progress in understanding the involvement of mitochondrial function in preserving liver function. In addition, a systematic review of mitokines-mediated immunomodulation in HCC is presented. Finally, the potential diagnostic and therapeutic roles of mitokines in HCC are prospected and summarized. Recent progress in mitokine research represents a new prospect for mitochondrial therapy. Considering the potential of mitokines to regulate immune function, investigating them as a relevant molecular target holds great promise for the diagnosis and treatment of HCC.
Effect of vitamin supplementation on polycystic ovary syndrome and key pathways implicated in its development: A Mendelian randomization study
Authors: Shen Jia-Yan , Xu Li , Ding Yang , Wu Xiao-Yun
Published: August 2023

Hepatocellular carcinoma (HCC) is one of the most prevalent tumors worldwide and the leading contributor to cancer-related deaths. The progression and metastasis of HCC are closely associated with altered mitochondrial metabolism, including mitochondrial stress response. Mitokines, soluble proteins produced and secreted in response to mitochondrial stress, play an essential immunomodulatory role. Immunotherapy has emerged as a crucial treatment option for HCC. However, a positive response to therapy is typically dependent on the interaction of tumor cells with immune regulation within the tumor microenvironment. Therefore, exploring the specific immunomodulatory mechanisms of mitokines in HCC is essential for improving the efficacy of immunotherapy. This study provides a comprehensive overview of the association between HCC and the immune microenvironment and highlights recent progress in understanding the involvement of mitochondrial function in preserving liver function. In addition, a systematic review of mitokines-mediated immunomodulation in HCC is presented. Finally, the potential diagnostic and therapeutic roles of mitokines in HCC are prospected and summarized. Recent progress in mitokine research represents a new prospect for mitochondrial therapy. Considering the potential of mitokines to regulate immune function, investigating them as a relevant molecular target holds great promise for the diagnosis and treatment of HCC.
Evaluation of childhood developing via optical coherence tomography-angiography in Qamdo, Tibet, China: A prospective cross-sectional, school-based study
Authors: Sun Ke-Xin , Xiang Yong-Guo , Zhang Tong , Yi Sheng-Lan , Xia Jiu-Yi , Yang Xin , Zheng Shi-Jie , Ji Yan , Wan Wen-Juan , Hu Ke
Published: August 2023

Hepatocellular carcinoma (HCC) is one of the most prevalent tumors worldwide and the leading contributor to cancer-related deaths. The progression and metastasis of HCC are closely associated with altered mitochondrial metabolism, including mitochondrial stress response. Mitokines, soluble proteins produced and secreted in response to mitochondrial stress, play an essential immunomodulatory role. Immunotherapy has emerged as a crucial treatment option for HCC. However, a positive response to therapy is typically dependent on the interaction of tumor cells with immune regulation within the tumor microenvironment. Therefore, exploring the specific immunomodulatory mechanisms of mitokines in HCC is essential for improving the efficacy of immunotherapy. This study provides a comprehensive overview of the association between HCC and the immune microenvironment and highlights recent progress in understanding the involvement of mitochondrial function in preserving liver function. In addition, a systematic review of mitokines-mediated immunomodulation in HCC is presented. Finally, the potential diagnostic and therapeutic roles of mitokines in HCC are prospected and summarized. Recent progress in mitokine research represents a new prospect for mitochondrial therapy. Considering the potential of mitokines to regulate immune function, investigating them as a relevant molecular target holds great promise for the diagnosis and treatment of HCC.
Imaged guided surgery during arteriovenous malformation of gastrointestinal stromal tumor using hyperspectral and indocyanine green visualization techniques: A case report
Authors: Wagner Tristan , Mustafov Onur , Hummels Marielle , Grabenkamp Anders , Thomas Michael N , Schiffmann Lars Mortimer , Bruns Christiane J , Stippel Dirk L , Wahba Roger
Published: August 2023

Hepatocellular carcinoma (HCC) is one of the most prevalent tumors worldwide and the leading contributor to cancer-related deaths. The progression and metastasis of HCC are closely associated with altered mitochondrial metabolism, including mitochondrial stress response. Mitokines, soluble proteins produced and secreted in response to mitochondrial stress, play an essential immunomodulatory role. Immunotherapy has emerged as a crucial treatment option for HCC. However, a positive response to therapy is typically dependent on the interaction of tumor cells with immune regulation within the tumor microenvironment. Therefore, exploring the specific immunomodulatory mechanisms of mitokines in HCC is essential for improving the efficacy of immunotherapy. This study provides a comprehensive overview of the association between HCC and the immune microenvironment and highlights recent progress in understanding the involvement of mitochondrial function in preserving liver function. In addition, a systematic review of mitokines-mediated immunomodulation in HCC is presented. Finally, the potential diagnostic and therapeutic roles of mitokines in HCC are prospected and summarized. Recent progress in mitokine research represents a new prospect for mitochondrial therapy. Considering the potential of mitokines to regulate immune function, investigating them as a relevant molecular target holds great promise for the diagnosis and treatment of HCC.
Nasopharyngeal carcinoma with synchronous breast metastasis: A case report
Authors: Lei Ye-Yan , Li Dong-Mei
Published: August 2023

Hepatocellular carcinoma (HCC) is one of the most prevalent tumors worldwide and the leading contributor to cancer-related deaths. The progression and metastasis of HCC are closely associated with altered mitochondrial metabolism, including mitochondrial stress response. Mitokines, soluble proteins produced and secreted in response to mitochondrial stress, play an essential immunomodulatory role. Immunotherapy has emerged as a crucial treatment option for HCC. However, a positive response to therapy is typically dependent on the interaction of tumor cells with immune regulation within the tumor microenvironment. Therefore, exploring the specific immunomodulatory mechanisms of mitokines in HCC is essential for improving the efficacy of immunotherapy. This study provides a comprehensive overview of the association between HCC and the immune microenvironment and highlights recent progress in understanding the involvement of mitochondrial function in preserving liver function. In addition, a systematic review of mitokines-mediated immunomodulation in HCC is presented. Finally, the potential diagnostic and therapeutic roles of mitokines in HCC are prospected and summarized. Recent progress in mitokine research represents a new prospect for mitochondrial therapy. Considering the potential of mitokines to regulate immune function, investigating them as a relevant molecular target holds great promise for the diagnosis and treatment of HCC.
Burnout in COVID-19 Residency
Authors: Kale Sachin , Dhabalia Pratik , Chalak Ajit , Patel Abhiraj , Chand Abhineet , Das Sonali
Published: August 2023

Introduction: Burnout is a syndrome denoting the outcome of chronic work stress which has not been managed successfully. Burnout has only sometimes been at the forefront of studies in healthcare, where patient care and management have received more attention. This study focuses particularly on burnout of residents and healthcare workers during the COVID-19 pandemic that has changed the working environment. Material and Methods: Questionnaires in the form of surveys have been used to receive feedback regarding work experience within the bubble of isolation and high patient load unique to COVID-19 pandemic. A full and complete analysis of the research is provided after the definition, description, and measurement of burnout are given. Results: According to a review of the burnout literature, burnout affects medical students, residents, and practicing doctors, with prevalence rates ranging from 28% to 45% for each group. First-year residency during the COVID-19 pandemic, in particular, is plagued with unmanageable burnout symptoms and a depleted support system. Burnout among residents is said to be caused by time demands, a lack of control, poor work organization, naturally challenging employment settings, and interpersonal connections. Workplace solutions might take the form of burnout education, workload adjustments, diversifying job roles, stress management training, mentorship, emotional intelligence seminars, and training in emotional intelligence. In addition, developing interpersonal and professional relationships, meditation, therapy, and exercise are examples of self-directed behavioral, social, and physical activities.. Conclusion: Educators should consider including pertinent instructions and interventions during the process of instructing resident doctors. In addition, they should actively become aware of burnout. Early detection aids in better management of burnout. Keywords: burnout, COVID-19, residency, work-life balance.
When all is not good – managing an adolescent with Osgood Schlatter disease
Authors: Agarwal Tushar , Suratwala Pooja
Published: August 2023

Anterior knee pain in children above 10 years of age is a part of every orthopaedic surgeon OPD practice. Osgood-Schlatter disease is the most common cause in skeletal of immature athletic children. It is a condition, in which the patellar tendon insertion on the tibial tuberosity becomes inflamed. It tends to occur more commonly in boys and it occurs in the second decade of life ( 10-15 years). It is a self limiting condition and and occurs secondary to repetitive extensor mechanism stress activities such as jumping and sprinting. OSD is a clinical diagnosis, and only radiographic evaluation may be done to confirm the diagnosis. Pain level dictates overall treatment, and management includes symptomatic treatment with ice and NSAIDs, as well as activity modification. & relative rest from inciting activities in association with lower extremities stretching exercises. In this paper we discuss the etiology, presentation, evaluation, and management of osgood schlatter disease. Keywords: osgood Schlatter disease , osteochondritis, anterior knee pain.
Non Standard Deviation – Managing angular deformities around the knee in young age
Authors: Sheth Binoti
Published: August 2023

Angular deformities around the knee in children are common presentations in day to day practice. While some of the deformities are physiological that need careful observation, the others are pathological and need timely medical or surgical intervention. Systematic evaluation of the deformity is the first step in making the correct decision about the management. The right choice of treatment, the correct timing and perfect execution of the technique are necessary for optimum outcome. This article describes the aetiology, clinicoradiological evaluation and management of angular deformities around the knee in children. Keywords: Knee, Angular deformity, Children.
Ultrahigh nonlinear optical absorption in MXene 2D films
Authors: Moss David
Published: August 2023

As a rapidly expanding family of two-dimensional (2D) materials, MXenes have recently gained considerable attention due to their appealing properties. Here, by developing a solution-based coating method that enables transfer-free and layer-by-layer film coating, we investigate the layer-dependent nonlinear optical absorption of Ti3C2Tx films ‒ an important member of the MXene family. By using the Z-scan technique, we characterize the nonlinear absorption of the prepared MXene films consisting of different numbers of monolayers. The results show that there is a strong and layer-dependent nonlinear absorption behavior, transitioning from revisable saturable absorption (RSA) to saturable absorption (SA) as the layer number increases from 5 to 30. Notably, the nonlinear absorption coefficient β varies significantly within this range, changing from ~7.13 × 102 cm/GW to ~-2.69 × 102 cm/GW. We also characterize the power-dependent nonlinear absorption of the MXene films at various incident laser intensities, and a decreasing trend in β is observed for increasing laser intensity. These results reveal the intriguing layer-dependent nonlinear optical properties of 2D MXene films, highlighting their versatility and potential for implementing high-performance nonlinear photonic devices.
Development of a relationship counselling website to identify and mitigate risk of intimate partner violence in the context of women’s PrEP use
Authors: Hartmann Miriam , Roberts Sarah T. , Triplett Noah , Tenza Siyanda , Maboa Onthatile , Mampuru Lydia , Mayisela Nonkululeko , Mbewe Dorica , Tolley Elizabeth E. , Reddy Krishnaveni , Palanee-Phillips Thesla , Montgomery Elizabeth T.
Published: August 2023

Discreet, accessible interventions are urgently needed to mitigate the risk of intimate-partner violence (IPV) and other relationship barriers that women encounter to using HIV prevention methods such as pre-exposure prophylaxis (PrEP). We adapted a counsellor-administered intervention, CHARISMA, into a mobile-optimized website to enhance accessibility and reduce human resources required for HIV prevention and relationship counseling. Using human-centered design and participatory methods, CHARISMA was adapted through workshops with former CHARISMA in-person intervention participants (n = 14; ages 18–45) and web development ‘sprints’ combined with cognitive interviews (n = 24). ‘CHARISMA mobile’ was then beta-tested with 81 women naïve to the in-person intervention. In beta-testing, participants used a ‘think aloud’ process to provide feedback on ease of use and rated design, functionality, comprehension, confidentiality, safety, and usefulness on a scale of 1 to 5 via a survey. Data were conducted in four rounds, interspersed with rapid assessment according to go/no-go criteria, and website adaptations. The updated website was pilot tested for ‘real-world’ feasibility and acceptability among 159 women using their own smartphones at a location of their choice. Feedback was measured via surveys and website analytics. Workshops and cognitive interviews generated insights on technology use, contextual adaptations, and confidentiality, which were integrated into the beta version. The beta version met all ‘go’ criteria and was further adapted for pilot testing. In pilot testing, users found the website was useful (mean rating 4.54 out of 5), safe (4.5 out of 5), and had few concerns about confidentiality (1.75, representing low concern). On average, users rated the website more than 4 stars out of 5. Beta and pilot-testing suggested the smartphone-optimized website was well-accepted, relevant, engaging, feasible to administer, discreet and safe. Results contributed to a refined website, suitable for adaptations to other contexts and further evaluation where outcomes related to PrEP use and relationships should be assessed.
Patients’ characteristics and 30-day mortality for those undergoing elective surgeries during the COVID-19 pandemic in Bangladesh
Authors: Ahmed Shakera , Karim Anwarul , Chowdhury Tanvir Kabir , Pulock Orindom Shing , Tamanna Nowrin , Akter Mastura , Biswas Puja , Afroz Fahmida , Pinky Susmita Dey , Alabbi Anika Nahrin , Jamil Tasnuba Raisa , Tasnim Zarin , Dev Dipa , Marma Mraching , Aziz Tasmiah Tahera , Hakim Hafiz Ahmed Nazmul , Basher A. K. M. Khairul , Shahin Nur Hossain Bhuiyan , Banu Tahmina
Published: August 2023

Background

The COVID-19 pandemic has significantly impacted the surgical practice throughout the world, including elective surgical care. This study investigated the characteristics of patients undergoing elective surgery, the prevalence of COVID-19 infection, the surgical procedures performed, and 30-day mortality in general and pediatric surgical settings in selected tertiary-level hospitals in Bangladesh from November 2020 to August 2021.

Methods

This serial cross-sectional study included 264 patients scheduled for elective surgeries during the study period. All patients underwent COVID-19 real-time polymerase chain reaction (RT-PCR) testing within 24 hours before surgery. Data on age, sex, common comorbidities, surgical procedures, and 30-day mortality were collected and analyzed. Furthermore, comparisons were made between COVID-19 positive and negative patients.

Results

The prevalence of COVID-19 infection among patients was 10.6%. Older age, a history of major surgery within the last three months, hypertension, and diabetes mellitus were significantly associated with COVID-19 infection. All COVID-19-negative patients underwent surgery, while only 46.4% of COVID-19-positive patients underwent surgery. The most common surgical procedures were related to the digestive system, breast, and urinary system. Only one patient (0.4%) died within 30 days after surgery among the COVID-19-negative patients, whereas two patients (7.1%) died among the COVID-19-positive patients: one before surgery and one after surgery.

Conclusions

This study provides valuable insights into the characteristics, burden of COVID-19 infection, and 30-day mortality of patients undergoing elective surgery in tertiary care centers in Bangladesh during the pandemic.
The state of online citizen science in Mongolia and its potential for environmental challenges
Authors: Batsaikhan Anudari , Jung Stephan , Hachinger Stephan
Published: August 2023

Mongolia is a sparsely populated Asian country covered by vast steppes, deserts, and forests. Few studies have been conducted on Online Citizen Science (OCS) activities in Mongolia. This study aims to analyze the state of OCS in Mongolia and, in a further step, to place it in an international context by comparing it with Germany and Japan, where OCS is already well established. Mongolia faces several environmental challenges, including climate change, land-use change, and intensive urbanization. OCS can help address these environmental challenges. Quantitative, qualitative, and literature-based analyses were conducted in this study. OCS has become more relevant in Mongolia since 2013, where projects have been introduced internationally rather than locally. A comparison with Germany and Japan showed that the use of web technologies and the degree of citizen participation in OCS projects are similar in these countries; however, the link to the United Nations Sustainable Development Goals (UN SDGs) may differ. To better respond to citizen needs and environmental challenges, additional local projects must be developed. Mongolia has the potential to enhance environmental monitoring and the networking of various actors using web technologies in citizen science.
Editorial
Authors: Batty Craig
Published: August 2023

This abstract introduces the 14.2 issue of the Journal of Screenwriting. It recognizes the wide-ranging approaches to screenwriting research and the range of topics that are covered. It also refers to the large number of non-screenwriting peer reviewers who are now assessing articles for the journal. It then goes on to outline the issue’s contents.
Analysis of the Impact of Wavelength-Dependent Physical Impairments Considering a Multiband Elastic Optical Network
Authors:   Federal University of Campina Grande, dos Santos-Junior Ademar , Arcanjo José Roberto , Pereira Helder , Almeida-Junior Raul ,   Federal University of Pernambuco
Published: August 2023

In this paper, we analyze the impact of wavelength- dependent physical impairments, specifically the optical fiber attenuation coefficient (α) and the optical amplifiers noise figure (NF), considering S, C and L bands in a multiband elastic optical network. The calls blocking probability and the distribution of modulation formats among the network accepted calls were used as evaluation metrics. The results obtained for the use of G-652.A optical fiber show that using α and NF with fixed values underestimates the most realistic scenario (α and NF dependent on wavelength). For the use of G-652.D optical fiber, it was possible to obtain a reduction of approximately 63.41% for S band, 95.60% for C band and 98.84% for L band, in terms of calls blocking probability, when the most realistic scenario was compared with the scenario most used in the literature (α and NF with fixed values). In addition, it was verified that, with the most realistic scenario, it was possible to obtain the distribution of more efficient modulation formats using the G-652.D optical fiber with C band.
imagens na construção da identidade do futebol brasileiro
Authors: Guimarães Carlos
Published: August 2023

O artigo faz uma trajetória histórica das imagens que ajudaram a constituir a identidade do futebol brasileiro. Parte-se da hipótese de que a construção das características e estereótipos do esporte no Brasil foram reforçadas com a seleção de imagens veiculadas pelo Canal 100, um cinejornal produzido entre 1959 e 1986, e que este perfil foi alterado com o fenômeno da futebolização (KOCH, 2021), gerando a ideia de um evento hiper-real (BAUDRILLARD, 1981). A base teórica para realizar esta comparação vem com Hartog (2013) e o regime de historicidade, que articula a relação do indivíduo com o tempo. Com isso, pretende-se, como resultado, apontar as transformações que modificaram esses estereótipos no imaginário do torcedor, a partir das suas relações com as imagens que determinam o que é o futebol brasileiro em suas particularidades.
Produção de subjetividades, vigilância e mídia:
Authors: Silva Heriton Vinícios Serrão , Xavier Monalisa Pontes
Published: August 2023

A sociedade de disciplina (FOUCAULT, 1987) e a sociedade de controle (DELEUZE, 1992), são conceitos que ganham corpo nas discursões sobre produção de subjetividades e mídia. Estudar a produção de subjetividades e a mídia nos levam a discutir sobre os jogos de forças diversos que buscam homogeneizar os modos de pensar, fazer e viver (SILVA, 2021) por meio da disciplina e do controle na vigilância. Levando em conta que a disciplina nasce de uma problemática moderna e o controle de uma problemática contemporânea, este artigo visa identificar rupturas e continuidades entre esses conceitos, por meio de uma revisão de literatura crítica. Perceberemos na pesquisa que outros conceitos importantes surgem na medida em que desenvolvemos a discussão.
Ailton Krenak e a defesa da inutilidade da vida
Authors: Maurer Camila
Published: August 2023

Ailton Krenak é um dos pensadores mais influentes da atualidade e uma das vozes mais potentes na defesa da causa indígena e ambiental. Sua produção intelectual recente está centrada na reflexão em torno de temas contemporâneos, tais como a pandemia de Covid-19 e o aquecimento global, a partir de uma perspectiva que tem como base a filosofia dos povos indígenas. O autor é, desde os anos 1980, uma das mais destacadas lideranças indígenas do país, tendo participado da fundação de entidades como a União das Nações Indígenas e a Aliança dos Povos da Floresta. Em setembro de 1987, proferiu um discurso histórico na tribuna da Câmara dos Deputados, durante a Assembleia Nacional Constituinte. De terno branco e rosto pintado com a tinta preta do jenipapo, protestou contra aqueles que ameaçavam os direitos dos povos originários e, em articulação com outras lideranças indígenas, conquistou um capítulo na Constituição destinado aos direitos de seu povo.
Immune Checkpoint Inhibitor-Induced Hemorrhagic Gastritis
Authors: Mathialagan Karthik , Tai Cheng-Hung , Sethi Samdish , Thomas Sumi , Loeser Caroline
Published: August 2023

Immune checkpoint inhibitors (ICIs) have been increasingly used in the treatment of several malignancies and may target cytotoxic T-lymphocyte-associated antigen-4, programmed cell death-1, and programmed cell death ligand 1, which work on maintaining peripheral immune tolerance. ICIs inhibit these ligands causing an immune-enhancing effect, leading to a wide spectrum of complications from mild mucositis to life-threatening pneumonitis or hepatitis. These complications are collectively called immune-related adverse events. Their prevalence has increased with a rise in ICI use, with rare manifestations being reported in popular literature. We present a case of hemorrhagic gastritis due to the anti-programmed cell death-1 antibody, pembrolizumab.
Measurement and evaluation of cement paste porosity by electrochemical impedance spectroscopy
Authors: Chalupová Jana , Němeček Jiří , Hybášek Vojtěch , Pommer Vojtěch , Němeček Jiří
Published: August 2023

Porosity is an important part of cement paste microstructure, which significantly influences the mechanical properties (especially durability and strength) of cement-based materials. Electrochemical impedance spectroscopy (EIS) is a non-destructive method used to measure the pore system utilizing a range of frequencies of electric current, which is fed to the cement paste by stainless steel electrodes. The pore volume is obtained from the pore resistance and the matrix capacitance measured by EIS. This paper deals with the evaluation of porosity based on resistance values from EIS on a sample of pure CEM I 42.5R Portland cement paste at 3 different hydration times (age 7, 14, 28 days).
Analysis of tunnel excavation based on linear DFN-FEM modelling
Authors: Lebeda Martin , Kabele Petr
Published: August 2023

Simulations of tunnel excavations have to take into account the natural occurrence of joints and faults in the surrounding rock mass, which dominantly control its mechanical response. In this paper, we present work in progress toward 3D finite element analysis of excavation using equivalent rock-mass properties derived from stochastically generated discrete fracture networks (DFNs). The equivalent stiffness is determined by volume averaging. Presently, we solve the problem linearly for an incremental change of the stress state. The fracture’s stiffness is assumed to depend on the initial normal stress acting in direction normal to it. However, within the solved incremental step, we assume the fracture’s stiffness to be constant. This assumption is acceptable for small stress changes. Since the fractures represented in the DFN model have preferred directions, the equivalent stiffness is anisotropic.
Extracting general knowledge of model parameters for clays out of numerous laboratory tests
Authors: Pavelcová Veronika , Janda Tomáš
Published: August 2023

This paper is concerned with the process of determining the material parameters of advanced constitutive models for clays. Provided results are applicable already in the early stages of geotechnical survey when no detailed data from laboratory tests of soils expected at construction site are known. A worldwide database of laboratory tests obtained during four year operation of web calibration application ExCalibre was used for this purpose. This application allows automatic calibration of three advanced constitutive soil models based on detailed data from triaxial and edometric tests. The paper describes the process of determining the confidence intervals of each material parameter of modified Cam-clay and hypoplastic clay models for low (CL) and high (CH) plasticity clay according to unified soil classification system (USCS) and tabulates their typical ranges. The purpose of presented work was to contribute to the use of advanced constitutive models among practical engineers.
Structural Analysis of the Protocols of the Elders of Zion
Authors: Hlaváčová Kateřina
Published: August 2023

This paper explores one of the most influential conspiracy theories of all time, as described in the Protocols of the Elders of Zion, by employing the method of structural analysis. The “master myth” of the Protocols represents a basic structure of the conspiracy narrative, whose motifs were subsequently modified throughout the 20th and 21st centuries according to current events and moods. However, to understand the pamphlet as a whole, it is also important to shed a little light on its specific historical context and the religious, political, and social fervour of the time, which eventually gave rise to this text. The text is one we can still consider a blueprint of contemporary conspiracy narratives about the global cabal that occupies a prominent place within the modern conspiracy culture.
Cosmic Prison Break: From Gnostic Movies to Conspiracist Cosmology
Authors: Kozák Jan A.
Published: August 2023

The article thematically and structurally analyses a group of films usually designated as “gnostic films”. These films share a common ideology as they postulate the existence of two worlds – one illusory and the other true. The hero must escape the false world and reach the true one. As the majority of gnostic films appeared at the turn of the millennium, the article also suggests what contributed to the emergence of these films. As the cosmology of the films bears a close similarity to the cosmology of conspiracy theories, the emergence of the films is shown to be a part of the sociocultural development of the conspiracist mindset entering the mainstream. In the 1990s, conspiracism was out of the closet and gained popularity, but it was not yet perceived as an imminent societal threat and therefore was not a taboo for Hollywood filmmakers. The 1990s were also the decade of a unipolar world order where the absence of an inimical Other engendered anxiety about the system itself, which is reflected in the analysed films.
How Cool Are Chemists?
Authors: Yue He , Han Lidong , Minton Donna J. , Deng Chunmei
Published: August 2023

The United Nations declared 2022 as the International Year of Basic Sciences for Sustainable Development (IYBSSD 2022) [1]. Since 2022 was also the 90th Anniversary of the founding of the Chinese Chemical Society (CCS), CSS celebrated these two important events with a special outreach project aimed at bringing attention to chemists and the important work they do while also highlighting the creative and humanistic aspects of scientific research [2]. The “Chemist is Cool” (sic) Research Group Style and Creativity Competition was a great success, and CCS was honored to have it be selected as one of the featured activities of the IYBSSD 2022.
„irgendwie müssen wir herausfinden, was passiert ist“ – Rezeption von Bilderbüchern als Ausgangspunkt für interaktionale Aushandlungsprozesse
Authors: Winter Evelina
Published: August 2023

Der Beitrag geht der Frage nach, wie Schülerinnen und Schüler am Beispiel des Bilderbuchs Wazn Teez? (Ellis 2017) die Narration in kollaborativen Leseprozessen aufbauen. Dabei liegt der Fokus auf ihren sprachlichen und schulischen Erfahrungen sowie den Unterschieden in der Interaktion bei der Bedeutungskonstruktion. Untersucht wurden in einer explorativ angelegten Studie Schülerinnen und Schüler mit den Erstsprachen Arabisch, Deutsch und Russisch.
Update on the distribution of the free-tailed bat, Nyctinomops aurispinosus (Chiroptera, Molossidae), with new records for the Caatinga and Brazilian Amazon
Authors: Sales Jeanneson , Pilatti Patricia , Zortéa Marlon , Costa Ricardo Carvalho , Rocha Patrício Adriano da
Published: August 2023

In Brazil, three out four bat species from the genus Nyctinomops are known. Most of occurrences of these species are based on captures with mist-nets. In this study, we extend the distribution of Nyctinomops aurispinosus in Brazil, providing new records for the Brazilian states of Mato Grosso (1), Roraima (1), Pará (2) and Pernambuco (1). We also confirm the use of new types of shelter by N. aurispinosus, such as rock crevices in dryland environments and river boulders. We provide new fundamental information about the biology, behavioural and ecological patterns of this species.
Crystal structure of 2-(3,5,5-trimethylcyclohex-2-en-1-ylidene)malononitrile, C12H14N2
Authors: Liu Yingfan , Wang Mengfei
Published: August 2023

C12H14N2, monoclinic, P21/c (no. 14), a = 10.16290(10) Å, b = 8.25800(10) Å, c = 13.4328(2), β = 95.910(1)∘, V = 1121.36(2) Å3, Z = 4, R

gt
(F) = 0.0380, wR

ref
(F
2) = 0.1126, T = 294 K.
Effect of aggregate characteristics on properties of cemented sand and gravel
Authors: Guo Lixia , Wu Zheng , Zhong Ling , Luo Yun
Published: August 2023

To improve the stability of cemented sand and gravel (CSG) dam construction materials, artificial aggregates can be selected to replace missing natural aggregates, and aggregate grading optimization can be carried out to meet the needs of engineering applications. This article uses finite-element analysis software to explore the influence of aggregate characteristics on the performance and destruction characteristics of CSG materials through numerical simulation. The results show that (1) with the increase of circular natural sand gravel aggregates, the peak stress and elastic modulus of the sample increase, while the strength also increases. (2) Compared to circular aggregates, polygonal aggregates have more edges and corners, which exacerbate the deformation disharmony between mortar and aggregates; the phenomenon of stress concentration is more obvious, so under the same loading step, the degree of damage of polygonal aggregates is greater than that of circular aggregates. (3) After the freeze–thaw cycle test, the deterioration of parameters in the CSG resulted in more severe damage and strength loss of the crushed stone aggregate than the circular aggregate sample. This conclusion can provide a reference for the design of CSG mix ratio in engineering sites.
Facile synthesis of novel interpenetrating polymeric network (IPN) from semi-IPN: comparative analysis of biodegradation studies for environmental remediation
Authors: Singh Anjali , Kaith Balbir Singh , Sud Dhiraj
Published: August 2023

This paper reports the novel synthesis of an interpenetrating polymer network (IPN) from semi-IPN. This semi-IPN is based on naturally occurring Colocasia esculenta corn starch. The toxicity levels were compared through various biodegradation methods. The polymer network was synthesised from the corresponding semi-IPN via a green pathway by using green solvent (water) and polyvinyl alcohol (PVA) as secondary monomer. The biodegradability of synthesized IPN was tested by vermi-composting, composting and soil burial methods. The study was divided into three stages that lasted up to 70 days. The synthesised IPN degraded 78.94 %, 69.23 % and 67.24 % within 70 days by vermi-composting, composting and burying in the soil, respectively. This was confirmed by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy with electron dispersion analysis (SEM-EDX) for each stage. Therefore, the system could be considered for agrochemical release without affecting soil fertility.
Digitale Gesamtkostenoptimierung
Authors: Grill-Kiefer Gerhard , Schröcker Stefan , Krasser Hannes , Körner Stefan
Published: August 2023

Die optimale und nachhaltige Gestaltung komplexer Prozesse in Produktionsunternehmen setzt ein strukturiertes Vorgehen in der Problemlösung voraus. Durch das breite Aufgabenspektrum und die miteinander in Konkurrenz stehenden Zielsetzungen gilt diese Rahmenbedingung insbesondere für das Supply Chain Management in der Automobilindustrie. Mit einem in mehrere Schritte gegliederten Prozess gelingen die Entwicklung und Anwendung eines Rechenmodells zur Optimierung der Gesamtkosten im Teileversorgungsprozess. Dieses stellt unter Einbindung der beteiligten Fachbereiche die ganzheitliche Optimierung der Versorgungsgesamtkosten und die Durchführung effizienter Planungsschleifen im operativen Betrieb sicher. Der Datenqualität kommt hierbei eine besondere Bedeutung zu.
Supply-Chain-Resilienz-Assessment
Authors: Rößler Markus Philipp , Gebhardt Michael Andreas , Augustin Alexander
Published: August 2023

Die Widerstandsfähigkeit oder Resilienz globaler Versorgungsketten ist in der heutigen vernetzten Geschäftswelt von entscheidender Bedeutung. Störungen können erhebliche Auswirkungen auf die betriebliche Effektivität und nicht zuletzt die Kundenzufriedenheit haben. Um diesen Herausforderungen zu begegnen, ist es entscheidend, die Resilienz der Lieferkette zu stärken. In diesem Beitrag wird das neu entwickelte Assessment zum Thema „Supply-Chain-Resilienz“ vorgestellt und anhand eines Anwendungsbeispiels in der Medizinproduktefertigung illustriert.
Prozessregelung ermöglicht gleichbleibende Fertigungsqualität bei der Implantatfertigung
Authors: Denkena Berend , Klemme Heinrich , Shanib Maruan , Kaiser Sebastian
Published: August 2023

Implantate weisen aufgrund der oftmals filigranen Struktur eine geringe werkstückseitige Steifigkeit und damit eine hohe prozesskraftbedingte Abdrängung auf. Um Toleranzanforderungen trotzdem zu erreichen, ist daher oft ein aufwändiger Einfahrprozess notwendig. Sich verändernde Rahmenbedingungen, wie z. B. zunehmender Werkzeugverschleiß, führen im Serienprozess zu weiteren Fertigungsfehlern, was eine ständige Prozessanpassung notwendig macht. In diesem Beitrag wird ein Regelungskonzept vorgestellt, das eine kontinuierliche Prozessanpassung zur Kompensation so entstehender Abweichungen selbständig durchführt.
Schnell, fachkundig und diskret: Sind verwaltungsinterne Kontrollen der bessere Rechtsschutz?
Authors: Heitzer Sonja , Kaufhold Ann-Katrin
Published: August 2023

In der Bankenunion erfreut sich verwaltungsinterner Rechtsschutz großer Beliebtheit. In anderen Bereichen des Unionsrechts lässt sich Ähnliches beobachten. Aus mitgliedstaatlicher Perspektive ist das eine überraschende Entwicklung, denn beispielsweise in Deutschland verliert das behördliche Vorverfahren seit Jahrzehnten kontinuierlich an Bedeutung. Anlass, das Potential verwaltungsinterner Kontrollen zu untersuchen, gibt auch der jüngste Vorschlag des EuGH zur Änderung der eigenen Satzung. Danach wären Rechtsmittel gegen Entscheidungen des EuG in Zukunft grundsätzlich unzulässig, wenn vor dem Gerichtsprozess bereits eine unabhänige behördeninterne Kontrolle der angegriffenen Verwaltungsentscheidung stattfgefunden hat. Wie dieser Vorschlag zu bewerten ist, hängt nicht zuletzt davon ab, ob die verwaltungsinternen Gremien die in sie gesetzten Hoffnungen erfüllen. Grund genug, die Strukturen und die bisherige Tätigkeit der drei Kontrollinstanzen der Bankenunion zu analysieren und eine Zwischenbilanz zu ziehen.
Antrag des Gerichtshofs nach Art. 281 Abs. 2 des Vertrags über die Arbeitsweise der Europäischen Union zur Änderung des Protokolls Nr. 3 über die Satzung des Gerichtshofs der Europäischen Union
Authors: EuGH
Published: August 2023

Der EuGH stellte am 30. 11. 2022 einen Antrag auf Änderung seiner Satzung. Die Satzung ist nach Art. 51 EUV Bestandteil der Verträge, weshalb er damit der Sache nach ein vereinfachtes autonomes Vertragsänderungsverfahren nach Art. 281 AEUV eingeleitet hat, dessen Durchführung in der Form eines ordentlichen Gesetzgebungsverfahrens dem Europäischen Parlament und dem Rat übertragen ist. Mit dem Antrag soll einmal erreicht werden, dass zukünftig in sechs Rechtsbereichen das EuG über Vorabentscheidungssuchen der nationalen Gerichte entscheidet (I.). Desweiteren soll ein Rechtsmittel gegen Entscheidungen des EuG in Zukunft nur noch in Ausnahmefällen zugelassen werden, wenn die Sache vor der Befassung des EuG schon durch eine unabhängige Beschwerdekammer kontrolliert wurde. Bislang gilt diese Einschränkung nur für vier ausgewählte Konstellationen, zukünftig würde sie auch sämtliche Rechtssachen erfassen, für deren Prüfung der „Beschwerdeausschuss“ des SRB (Appeal Panel, AP) sowie der Gemeinsamen Beschwerdeausschuss der Europäischen Aufsichtsbehörden EBA, EIOPA und ESMA (Joint Board of Appeal, JBoA). zuständig sind (II.).
Cultura de Prevención de Riesgos en la Universidad Enrique Guzmán y Valle-La Cantuta
Authors: Calderón-Pacheco Rosabel , Malca-Casavilca Nora
Published: August 2023

Este artículo, bajo una revisión documental, analiza la importancia de la implementación de herramientas de gestión de seguridad en una institución de educación superior, a través de una muestra de 28 docentes, a través de la administración de encuestas para la evaluación. La investigación realizada es no experimental, descriptivo-correlacional. A manera de conclusión se evidencia que la implementación de herramientas de gestión de seguridad como el plan de seguridad, identificación de peligros, evaluación y control de riesgos (IPERC), protocolos de trabajo, entre otros permitió mejorar el ambiente de trabajo del docente, a través del conocimiento de la exposición a riesgos en el centro laboral y las acciones a realizar para eliminar o minimizar el factor de riesgo. Además, de la concientización de la presencia del docente en la realización del desarrollo del plan y programa de seguridad de la universidad. Es recomendable la continuidad de las evaluaciones periódicas para medir la evolución de la cultura de prevención e ir ajustando el uso y/o implementación de las herramientas de gestión basándose en el resultado de la evaluación, generando que se establezca un modelo de intervención circular frente a la seguridad y salud de los docentes.
Evaluación de los cambios de la cubierta forestal en la microcuenca Huacamayo, Madre de Dios
Authors: Montenegro Pisfil Jaime Federico , Malca-Casavilca Nora Rosa Concepción , Jave Nakayo Jorge Leonardo
Published: August 2023

El objetivo de este trabajo de investigación fue evaluar la trasformación del área forestal en la Microcuenca del río Huacamayo. Se emplearon 6 fotografías satelitales Landsat de los años 1999, 2010, 2014, 2016, 2018, 2020. Durante 1999-2010 se observó una pérdida de 13.5 km2 de la cubierta forestal, los periodos 2014, 2018, 2020, mostraron progresivos retrocesos del bosque húmedo tropical, 4.4 km2, 3.1 km2 y 7.5 km2, respectivamente. En los 21 años se han perdido 28.5 km2 de bosque de la Microcuenca reportándose un porcentaje de deforestación -1.2% anual; entre 1999-2010 se evidenció la tasa de deforestación más alta, -1.7%. Para el año 2031, el modelo para el bosque tropical en la Microcuenca estimó un área resultante de 39 km2, demostrando la progresiva disminución de este. Este estudio direccionara la conservación y manejo del área forestal de la Microcuenca
Análisis de la normativa aplicable por el derrame de hidrocarburos en Ventanilla
Authors: Lazo Oscanoa Carlos Alberto , Alzamora Solís Keyla Xiomara , Llanos García Jorge Rolando , Solís Mendoza Katherine Rosario Elizabeth , Cortijo Guerrero Maria Guadalupe , Perales Palomino Nicole Daniela , Suclupe Benites Yoana , Puraca Mamani Wilmer José
Published: August 2023

El derrame de petróleo frente a las costas de Ventanilla y otros distritos, cuyo responsable es la Refinería La Pampilla, provocó un desastre ambiental a gran escala; el OEFA reportó la afectación de un área de 11,061 hay 11,900 barriles de petróleo. La presente investigación tiene por objetivo analizar desde un punto de vista normativo las competencias que deberían asumir las diversas instituciones en el caso. La investigación llevada a cabo mediante un enfoque cualitativo es de tipo descriptiva por la recopilación de datos y selección de información de diversas fuentes. En cuanto a los resultados, con respecto a la responsabilidad administrativa, por actuación del OEFA, se han iniciado cinco procesos administrativos sancionadores de las dieciséis medidas administrativas dictadas. Sobre la responsabilidad civil, se contempla la indemnización. En cuanto a la responsabilidad penal, rige el delito de contaminación contemplado en el artículo 304 del Código Penal. Respecto a la responsabilidad ambiental, se contemplan medidas para la restauración y recuperación y el costo de los riesgos o daños generados. Se concluye precisando la normativa ambiental aplicable sobre los procedimientos que se deben asumir y sobre la responsabilidad ambiental, se identificó la falta de normativa peruana.
Desarrollo de un Índice Numérico de Calidad de Agua Marina para la pesca y maricultura en la costa central del Perú
Authors: Orozco Moreyra Rita Esther , Vivas-Aguas Lizbeth-Janet , Alcantara Boza Alejandro
Published: August 2023

El estudio tuvo como objetivo, desarrollar un índice numérico integrado de calidad de agua de mar para los usos de pesca y maricultura ICAMPA para la zona marina costera de Supe, considerada entre las siete bahías más importantes de la actividad pesquera en el Perú. En el área de estudio, se evaluaron 15 estaciones a nivel de superficie y fondo. Se seleccionaron 10 parámetros que fueron definidos por su nivel de importancia y que definen la calidad acuática ambiental de esta área que es importante para la extracción de recursos hidrobiológicos. Los valores obtenidos utilizando el índice, desarrollado en la presente investigación para pesca y maricultura en la bahía de Supe, evidenció que la zona centro ubicada frente a la desembocadura del río Pativilca y la zona sur se encuentran afectadas por las plantas pesqueras industriales presentes en esta área. Se concluye que el ICAMPA, obtenido es estadísticamente significativo y adecuado para el desarrollo de las actividades de pesca y maricultura en la bahía de Supe y puede ser aplicable a otras zonas costeras del litoral peruano donde se desarrollen estas actividades. De esta manera se constituye en una herramienta útil para la gestión y manejo sostenible de las zonas costeras.
Construcción de un modelo de gestión de costos en una mina subterránea
Authors: Escudero Simon William , Guadalupe Gómez Enrique , Romero Baylon Alfonso
Published: August 2023

Las actividades mineras están asociadas a la influencia de factores externos e internos. Las empresas no tienen control sobre los factores externos como la oferta y demanda de los metales, sin embargo, los factores internos como la optimización y gestión de sus procesos es responsabilidad de sus directivos y supervisores. Los costos es resultado de la mejora continua, gestión de los procesos, gestión de la seguridad en el trabajo, cuidado del medio ambiente y de su relacionamiento social. En este contexto es necesario contar con un modelo adecuado de costos.  Esta investigación tiene por objetivo mostrar la construcción de un nuevo modelo para la gestión de los costos en una mina subterránea que facilite el seguimiento, control y toma de decisiones en las operaciones diarias. Uno de los reportes que se generan del MOGECOMS es por centro de costos este presenta el presupuesto de diciembre, lo ejecutado de diciembre y la desviación de diciembre, donde la desviación es la suma de la desviación técnica más la desviación económica de diciembre, también se presenta el presupuesto acumulado a diciembre, ejecutado acumulado a diciembre y desviación acumulada a diciembre, donde la desviación acumulada es la suma de la desviación técnica más la desviación económica. Además, el modelo de gestión de costos permite generar costos por estructuras de mineralizadas (veta, cuerpo, manto, cuerpo), costos por métodos de explotación (corte y relleno, sublevel stoping), costos fijos y costos variables, costos por naturalezas de gastos, determinar KPI de las operaciones. Mediante el análisis de estos reportes permite tomar decisiones y gestionar las operaciones de la mina, consecuentemente hacer que las operaciones mineras sean sostenibles en el tiempo.