bluuebunny/crossref_metadata_2025 huggingface dataset:
Strategies for Forming the Well-Being of Student Families (By the Results of In-Depth Interview)
Authors:   Institute for Demographic Research – Branch of the Federal Center of Theoretical and Applied Sociology of the Russian Academy of Sciences, Rostovskaya Tamara , Vasilieva Ekaterina ,   Volgograd State University
Published: September 2023

The methodological basis of the research is built within the framework of understanding sociology and the theory of social action by M. Weber. The paper reveals the content of the concept of a prosperous young family, highlights the parameters of the well-being of a student family. The empirical base of the study is the data of indepth interviews (n = 80) conducted with members of student families from 10 regions of Russia. The method of "grounded theory" and the method of reconstructing the life path of the family were used to process the obtained results. The main objective of the study is to identify strategies for the formation of well-being of Russian student families for the implementation of marital and reproductive behavior as well as systematization of problems affecting the decline in well-being. The main problem is financial difficulties of student families. The socio-economic status of a student family depends on many conditions. For example, status of the spouses' parent family, age of spouses, willingness and ability to combine work and study, availability of a separate housing or resources for rent for a young family. In addition to material problems married students have psychological difficulties adapting to new roles. With appearing children affordable and high-quality medical care, assistance in child care, and inclusion of educational organizations in the development of an individual training plan are necessary. Reproductive orientations of students correspond to the practices of goal-oriented and value-rational behavior (with the exception of cases of unplanned pregnancy) because the birth of children is associated with responsibility. It is revealed that the strategies for the formation of well-being of student families are influenced by many factors. Firstly, there is impact of scenarios for the development of premarital relationships. For example, the transformation of youth romantic relationships and youth love into marital relations, effective joint activity, shared values as the basis for marriage, acquaintance in friends' company and at work, acquaintance through social networks, "influence of parents", "need for legal consolidation of relationships", "responsibility for unplanned pregnancy". Secondly, the reproductive attitudes of married families is also significant. Thirdly, there is influence of family measures and demographic policy implemented in the region and the resources of educational organizations for effective assistance to a young family.
A Systematical Evaluation on the Leyla Gencer Voice Competition
Authors: EVREN Gül Fahriye , GÖK Özgül
Published: September 2023

Several prestigious classical music competitions are organized in the national and international fields. These competitions, organized in the field such as performance and composition, motivate many young artists and allow them to achieve significant successes. The Leyla Gencer Voice Competition is an international and worldwide-known voice competition, which is the oldest and most important competition held in Turkey in the opera genre. Leyla Gencer, known as La Diva Turca and entitled as State Artist by the Turkish Republic, is one of our world-renowned artists, and with her pioneering character of music, she has made significant contributions to the promotion of the art of opera to our country and the announcement of Turkish opera singers to the world. Leyla Gencer Voice Competition has been organized with different frequencies starting from 1995 until 2018. This competition has been also held in the years after her death and it has maintained its prestige until today. From the past to the present, numerous great performers started their careers with prestigious music competitions such as Leyla Gencer Voice Competition. They achieved important career positions with their success of the competitions and now they are worldwide known artists. In this study, information about the life of Leyla Gencer, who made great contributions to the development of Turkish Opera art, was given; and the findings of the voice contest organized in her name were tabulated and interpreted by using document analysis methodology. The findings were created by systematical analysis of the information on the official website of the Leyla Gencer Voice Competition and the one in the archive of the Istanbul Foundation for Culture and Arts. Data regarding terms and conditions of the competition, audition processes, winners, awards, jury members for the preliminary auditions and finals, winners by country, Turkish award winners, number of awards received by Turkish award winners, distribution of award winners by voice type, distribution of award winners by gender, organizing institutions and gala concerts were evaluated and presented by classifying them according to years. As a result, the importance of the increase in prestigious competitions in our country, the increase in the motivation of young soloists, the creation of an archive of the competitions, and most importantly the establishment of a national federation of music competitions were emphasized.
ASSESSING FUEL FRAGMENTATION IN AN OXIDIZING ATMOSPHERE FOR HYBRID ROCKET PROPELLANT SAFETY COMPREHENSION
Authors: Takahashi Akiyo , Ode Takumi , Ogasawara Daigo , Tsubokura Subaru , Takahashi Kenichi , Takahashi Yoshiaki , Saburi Tei , Kubota Shiro
Published: September 2023

Although hybrid rockets are considered safe, when solid fuel forms dust during impact and mixes with leaked oxidizer, a combustible gas mixture might form and burn rapidly. Therefore, to ascertain whether or not solid fuels burn by fragmentation in an oxidizing atmosphere, efforts are being made to fragment microcrystalline wax, which tends to generate dust among solid fuels under air and oxygen atmospheres. Earlier test results showed differences between results obtained in oxygen and air; however, the influence of experimental configurations cannot be ruled out. Therefore, experiments were conducted again with the air and oxygen experimental configurations combined. A transparent balloon was filled with a specimen and air or oxygen. A detonator and explosives were used to fragment the specimen. Then, the fragmentation was observed and a pressure-time history around the specimen was obtained. In all, nine experiments were conducted while varying the atmosphere, explosive mass, and presence of specimens. In all of the experiments, the pressure-time history comparisons under oxygen showed the same or higher peak overpressure and impulse compared to air. Furthermore, movies taken of experiments under an oxygen atmosphere showed strong luminescence, indicating clearly that combustion occurred in the oxygen atmosphere. The impulse values were highest in the oxygen atmosphere where the specimen was present, suggesting that the specimen burned.
The Impact of Regional Economic Conditions on Place Branding Results: The Survival Analysis Approach
Authors:   Vladimir Branch of the Russian Presidential Academy of National Economy and Public Administration, Makarov P. Yu. , Chub A. A. ,   Financial University under the Government of the Russian Federation
Published: September 2023

Place branding became a part of regional development processes; therefore, regional conditions could affect the place branding success. Nevertheless, studies on place branding success are mostly focused on management issues, and the role of regional conditions is yet to be revealed. In this regard, the paper aims to explore how regional economic (including social and spatial) conditions affect the results of place branding activity. We assumed that regional conditions have a certain impact on place branding activities, yielding better or worse place brands survival, which we treated as the fact of observable place brand attributes continuing to exist. To test this hypothesis, a survival analysis on brands of 15 Russian regions was performed for the period from 2010 to 2021. Using the Kaplan-Meier method, we examined the impact of seven variables on place brands survival. The obtained findings confirm the positive impact on brands survival of such variables as gross regional product (GRP) per capita, regional investment, and migration attractiveness. The following variables have a negative impact: unemployment rate, the adjacency to regions already having place brands. Additionally, place brands of regions with administrative centres in smaller cities have a better survival rate than the ones with bigger cities. Finally, the impact of change of the federal subject’s head on survival was not confirmed. Thus, the present article contributes to place branding studies by unveiling the influence of regional conditions on place branding outputs and extends the methods of place branding research by using the survival analysis.
Devamlılık veya Değişim? Caydırıcılık ve NATO’nun Nükleer Stratejik Tutumu
Authors: KOÇPINAR Ayhan Türker
Published: September 2023

Uluslararası güvenlik ortamında nükleer silahlar caydırıcılık stratejilerinin önemli bir unsuru olmuştur. Neo-realizm kuramının, uluslararası sistemde nükleer silahların küresel aktörler arasındaki dengeyi sürdürmede ve savaş riskini azaltmada önemli bir rol oynadığını savunan bakış açısı etkisini devam ettirmektedir. Nükleer güç NATO’nun kolektif savunma stratejilerinde de etkili bir rol oynamıştır. Soğuk Savaş süresince strateji, Varşova Paktı sınırlarının genişlemesini önleme üzerine kurulmuştur. NATO, Topyekûn Mukabele (Massive Retaliation) ve Esnek Karşılık (Flexible Response) stratejik nükleer tutumları uygulamıştır. Her iki tutum da uluslararası güvenlik ortamını farklı açılardan etkilemiştir. Nükleer politikalar Soğuk Savaşın sona ermesinden sonra da güvenlik ortamını etkilemeye devam etmiştir. Nükleer silahların olmadığı bir dünya yaratma çabalarına rağmen, stratejik belgeler, dünyanın diğer bölgelerinde nükleer silah depoları bulunduğu sürece NATO’nun nükleer silah kapasitesini koruyacağını teyit eder nitelikte olmuştur. Soğuk Savaş’tan sonra, Rusya Federasyonu’nun politikaları, Çin’in ‘barışçıl yükselişi’ sorusu, nükleer silahların yaygınlaşması gibi konular ortaya çıkmıştır. Bu çalışmada neo-realizm kuramının, uluslararası sistemde nükleer silahların devletler arasındaki dengeyi sürdürmede ve savaş riskini azaltmada önemli bir rol oynadığını savunan teorik çerçevesi kapsamında, Soğuk Savaş dönemi ve sonrasında nükleer caydırıcılık bağlamında NATO’nun stratejik nükleer tutumu analiz edilecektir. NATO’nun nükleer kabiliyeti caydırıcılığın önemli bir bileşenidir. Ancak Soğuk Savaş sonrası dönemde nükleer caydırıcılığa yönelik tutumun NATO politikalarına etkisinin Soğuk Savaş dönemine göre azaldığı düşünülmektedir. Son dönemde ortaya çıkan yeni güvenlik sınamaları nedeniyle caydırıcılık bağlamında nükleer silahların ve stratejik nükleer tutumların öneminin artacağı öngörülmektedir.
Mouse Brain Perfusion and Flash Freezing v1
Authors: Institute Allen
Published: September 2023

This protocol is used for transcardial perfusion with HEPES-Sucrose Cutting Solution (Referred as HEPES hereafter), followed by fast brain dissection and flash freezing.
KAPP-Sen TMC: Dissociation of Pancreatic Islets (recovered) v1
Authors: Alcoforado Diniz Juliana , Garofalo Jessica , Robson Paul
Published: September 2023

The dispersed samples were shipped cold from PRODOLABS. Prior to scRNA-seq dispersed samples from brain dead donor’s pancreatic islets were recovered and dissociated as follows.
Dampak Pandemi Covid-19 dalam Keharmonisan Keluarga
Authors: Fauziah Nine , Afrizal Stevany
Published: September 2023

Tidak dapat dipungkiri bahwa adanya wabah virus covid-19 akan berdampak pada sistem kehidupan di dalamnya, seperti pendapatan finansial yang menurun karena beberapa hal yang melatarbelakanginya, meningkatnya tingkat perceraian serta tidak berfungsinya peran dan fungsi keluarga dengan baik. Sehingga hal ini akan mempengaruhi keharmonisan keluarga, keharmonisan keluarga bisa dikatakan apabila seluruh anggota keluarga yang ada di dalamnya merasa nyaman, tenang, bahagia dan merasa saling melindungi satu sama lain. Dengan demikian hal ini penting untuk dipertahankan di tengah pandemi covid-19, sehingga tidak mengakibatkan keretakan dalam sebuah keluarga hingga mungkin menyebabkan suatu hal yang sama sekali tidak diinginkan sebelumnya. Artikel ini menggunakan metode kualitatif deskriptif, dengan memaparkan hasil penelitian yang sesuai dengan fakta di lapangan dengan cara observasi, wawancara dan dokumentasi.
Resiliensi Pelaku Wisata Masyarakat Desa Ngadas dalam Menghadapi Pandemi COVID-19
Authors: Ba’abdullah Muchammad Ersa , Kurniawati Elya , Santi Rozakiyah Desy
Published: September 2023

Penelitian ini adalah untuk mengetahui, bagaimana Resiliensi pelaku wisata masyarakat desa Ngadas dalam menghadapi pandemi COVID-19, bagaimana pelaku wisata melakukan adaptasi pariwisata dalam masa pandemi COVID-19. Pada penelitian ini penulis menggunakan metode penelitian kualitatif dengan pendekatan fenomenonolgi. Metodologi penelitian ini menggunakan pendekatan kualitatif, menggunakan observasi, wawancara mendalam dengan pelaku wisata di TNBTS. Hasil dari penelitian ini menggambarkan bahwa resiliensi pelaku wisata masyarakat Desa Ngadas dalam menghadapi pandemi COVID-19 dalam melakukan resiliensi kembali pada pekerjaan utama sebelum menjalankan wisata yaitu sektor pertanian seperti sayur dalam menjalankan kegiatan ekonomi dan memenuhi kebutuan keluarga selama pandemi COVID-19.
Analisis Stigmatisasi terhadap Perilaku Diskriminasi Agama Leluhur dan Kepercayaan Lokal
Authors: Anggraeni Nekha Dewi , Rakhmawati Adiyatma , Hidayah Rochamah Nur , Tresandya Noven , Pramono Didi
Published: September 2023

Tujuan penulisan artikel ini adalah untuk memberikan gambaran dan penjelasan mengenai stigmatisasi keberadaan agama leluhur dan kepercayaan lokal. Metode penelitian yang digunakan adalah pendekatan kualitatif dengan menggunakan studi kepustakan untuk mengumpulkan data sebagai bahan penulisan artikel ini. Pada artikel ini penulis memberikan analisisnya mengenai salah satu agama leluhur yang terkena stigma yaitu agama marapu dan juga aliran kepercayaan kebatinan. Penulis juga mencoba untuk menjelaskan mengenai bentuk perilaku diskriminatif terhadap agama dan kepercayaan leluhur yang disertai dengan dampak yang ditimbulkan dari adanya perilaku tersebut. Masih sangat minim bentuk kesadaran dari masyarakat untuk tidak melakukan stigmatisasi terhadap agama leluhur dan juga kepercayaan lokal, maka dari itu diperlukannya literasi pemahaman yang luas terkait masalah ini.
A Neoteric View of sp2 Amorphous Carbon
Authors:   Peoples’ Friendship University of Russia, Sheka Elena F.
Published: September 2023

Presented is a concentrated synopsis of facilities of empirical and virtual analytics that, once applied, have provided a fully new vision of sp2 amorphous carbons. This study proved that the solids are multilevel structures, started with the first-level basic structural units (BSUs) and accomplished as macroscopic agglomerates of globular structures, consisting, in its turn, of stacked BSUs. BSUs present necklaced graphene molecules, size, and shape of which are governed by the relevant graphene domains while chemical composition in addition to basic carbon is controlled with heteroatoms of the necklaces. This study shows that BSUs and stacks of BSUs determine the short-range order of the solids and are the main subject of the applied analytics. The synopsis consists of two parts related to empirical and virtual analytics. The former is composed of sections related to structural determination, total and atomic chemical content evaluation and elicitation of the covalent bond composition. The second presents new analytic approaches based on the Digital Twins concept and virtual vibrational spectrometry. The synopsis is configured as an atlas composed of generalized pictures accompanied with necessary explanations to be discussed in detail in the extended references.
AZERBAYCAN’DA FISHER ETKİSİNİN GEÇERLİLİĞİ: BİR ZAMAN SERİSİ ANALİZİ -1994-2015
Authors: ELİBEYLİ İlahe , AKBULAEV Nurhodja
Published: September 2023

Küreselleşen dünyamız döviz kurlarının önemini daha da artırmaktadır. Döviz Kurlarının öneminin artması farklı yaklaşımların ortaya çıkmasına neden olmuştur. Fisher Etkisi(Hipotezi) de bu yaklaşımlar arasında en meşhur olanıdır. Fisher etkisi (Hipotezi) enflasyon oranı ile nominal faiz oranları arasında pozitif ilişki olduğunu açığa çıkaran yaklaşımdır. Bu konuda Azerbaycan örneği üzerinde çalışmalar daha önce yapılmamıştır ki, bu da konunun önemini ortaya koymaktadır. Çalışmada 1994-2015 dönemine ilişkin Azerbaycan ekonomisine ilişkin veriler kullanılarak Fisher Etkisinin geçerli olup-olmadığı ampirik olarak test edilmesi amaçlanmıştır. Azerbaycan’da 2006 yılında “manatın denominasyon”u uygulandığı için, aynı zamanda 2015 yılında devalüasyon olduğu için araştırma sonuçlarında sapmalar olacağı hipotezinden yola çıkarak, sonuçların daha doğru bir şekilde yansıtılması adına araştırma üç kısma ayrılmaktadır. Elde edilen verilerin sayısal olarak özetlenmesi açısından tanımlayıcı istatistikler, bu değişkenler arasında ilişki olupolmadığını, arada ilişki söz konusu ise ilişkinin yönünü ve gücünü belirlemek için Korelasyon analizi, bu değişkenler arasındakı ilişkiyi belirlemek ve bu ilişkiyi kullanarak konu ile ilgili tahminler ve kestirimler yapa bilmek amacıyla Regresyon analizi uygulanmıştır. Analiz sonucunda, Azerbaycan ekonomisi için veya Azerbacan ekonomisin hiç bir aşamasında (Hiperenflasyon sonrası, para birimindeki değişiklikten önce veya sonra, devalvasyondan önce veya sonra) Fisher etkisinin geçerli olmadığı ortaya çıkmıştır.
Biogenetic human rights: a new structural element in the system of the fourth generation of rights
Authors: Galyukova M. I.
Published: September 2023

The concept of human rights is a dynamic legal phenomenon. The main feature of all three generations of rights is that they are a powerful constitutional and moral-legal foundation for the development of the last fourth generation of rights. Traditionally, the fourth generation of rights includes somatic, reproductive and informational rights. The article substantiates the innovative idea of identifying an independent category of rights — biogenetic rights. The author for the first time in the scientific literature uses the term “biogenetic rights”, offers the definition and content of a new category of rights. The main conclusion of the study is that the generation of biogenetic rights should be aimed at protecting the human genome, genetic information, ensuring the biosecurity of a person, society, state and mankind.
El régimen señorial en Asturias del siglo XVI al XIX
Authors: Campos Álvarez Álvaro
Published: September 2023

Este trabajo tiene como objetivo el estudio de los señoríos en el Principado de Asturias desde el siglo XVI hasta el XIX, ya que a partir de ese momento solo se mantendría su base solariega. En primer lugar, me he centrado en los señoríos eclesiásticos debido tanto a su importancia en la región como a su compleja evolución. He llevado a cabo un análisis de todos sus aspectos, desde las facultades del señor hasta las desvinculaciones de su jurisdicción en el siglo XVI para su posterior venta. En segundo lugar, trato de abordar el extenso contenido de los señoríos laicos, centrándome en el siglo XVIII que es el periodo del que más información contamos. Para una lectura fácil y sencilla, he organizado estos lugares en función de la casa nobiliaria a quien pertenecían. En tercer y último lugar, he analizado los distintos hechos que desembocaron en la abolición de estos señoríos en España y de manera más breve en Asturias, debido a la escasa información de la que contamos.
Experience in the use of microcontroller platforms and computer technologies in experimental researches of automotive and tractor machinery
Authors: Esakov Aleksei E. , Bernatskii Vladislav V. , Esenovskii-Lashkov Mikhail Yu.
Published: September 2023

BACKGROUND: The current level of research and development work involves the use of systems based on programmable electronics. At the current level of engineering, the development of these systems is expedient to carry out using specialized software. At the same time, a systemic approach to the methodology for using the mentioned tools has not been fully formed yet, which necessitates the consideration of the relevant issues of theory and practice.
AIMS: The attempt to form the principles of the mentioned systemic approach, based on the idea of the integrated hardware and software use, where the complementarity of their capabilities ensures the appearance of a pronounced emergence.
METHODS: The article contains an analytical review and categorization of modern tools that allow to support research in their preparation, carrying out and results processing. As a particular example of their successful combined application, a computerized educational laboratory installation designed by the authors for balancing and calibrating the torque measurement system at a driveshaft of a passenger car is considered.
RESULTS: The article materials contain a description of design and an operation principle of the mentioned installation, a consistent consideration of those specific tools that were used in its development, а information regarding the basic capabilities, the most significant characteristics and features of these tools, as well as the trial tests results and their interpretation.
CONCLUSIONS: The approach described by the authors makes it possible to rationally approach the solution of problems related to the development and use of data measurement systems for experimental studies of automotive and tractor machinery.
In memory of Sergey V. Bakhmutov
Authors: Arseniev Sergey E.
Published: September 2023

On April 7, 2023, our colleague, Doctor of Technical Sciences, Professor, Honorary Worker of Higher Professional Education, Deputy General Director for Science of the Central Research Automobile and Automotive Institute (NAMI), a member of the editorial boards of the Tractors and Agricultural Machines and Izvestiya MAMI journals Sergey V. Bakhmutov passed away.Sergey V. Bakhmutov was a prominent specialist in the following scientific fields: vehicle dynamics, active safety, optimization of design parameters, highly automated transport and technological facilities.He was the author and co-author of about 170 scientific papers, including 20 books, 22 certificates of authorship and patents for inventions and utility models.
Antibiotic-related adverse events and risk factors in hospitalized patients: a prospective cohort study
Authors: SOYSAL Orcun , ŞENCAN İrfan , KORKMAZ Nesibe
Published: September 2023

Purpose: The objective of this study is to identify antibiotic-related adverse events and risk factors in hospitalized patients.

Materials and Methods: This prospective cohort study included 776 inpatients who received antibiotic treatment between January 2019 and December 2020. Patients who experienced "definite" or "probable" adverse drug events (ADE) were examined using the World Health Organization-Uppsala Monitoring Center (WHO-UMC) criteria. The definition and severity criteria for antibiotic-related adverse events were determined according to the Common Terminology Criteria for Adverse Events (CTCAE).

Results: The overall rate of antibiotic-associated ADE was 7.9 (95%CI, 6.8-9.1) per 1000 person-days. The study identified a total of 152 adverse events in 125 patients who experienced ADE. Among the 152 adverse events, 63 (41.4%) were severe, and 89 (58.6%) were non-severe. Independent risk factors for ADE included the number of comorbidities (up to 4 times higher increased risk), number of drugs used, and duration of antibiotic administration (up to 12.3 times higher and 8% increased risk for each additional day). The most common side effects were hematological, with 45 (29.6%) cases reported in the hematological system advers events.

Conclusion: The management of antibiotic durations, which is a controllable factor in the development of antibiotic-related adverse events, is crucial. Rational use of antibiotics is essential, not only in terms of preventing the development of resistance but also in terms of reducing the frequency of adverse events that may become life-threatening.
The protective effect of tangeretin and pomegranate separately and in combination on ethanol-induced acute gastric ulcer model
Authors: SUSAM Solmaz , İLHAN Nevin , TEDİK Fatma , BERK Buket , İLHAN Ayşe Şebnem
Published: September 2023

Purpose: This study was designed to find an answer to the question, "Is it beneficial to use pomegranate (POM) and tangeretin (TAN) separately or in combination, for the prevention of acute gastric ulcer?".

Materials and Methods: The gastroprotective effect of tangeretin and pomegranate was determined by measuring the levels of the selected inflammatory cytokines [tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), IL-1β and IL-10], lipid peroxides, and enzymatic activities of antioxidants in gastric tissue samples.

Results: When all groups are written as control, gastric ulcer, POM+EtOH, TAN+EtOH and POM+TAN+EtOH, respectively; IL-1β cytokine levels were measured as 0.147, 0.24, 0.228, 0.195 and 0.182 pg/g protein. IL-6 levels; 16,857, 25,923, 19,797, 18,838 and 17,896 pg/mg protein. TNF-α levels were 39,916, 49.97, 44,678, 41,673 and 40,844 pg/mg protein. Finally, IL-10 levels were measured as 33,496, 28,071, 29,693, 30,073 and 30,008 pg/mg protein. SOD activities were determined as 18,038, 13,731, 15,506, 14,439, and 15,943. CAT activities were 674,638, 639,964, 673,382, 664,691, and 671,203. Protein carbonyl levels were measured as 26,799, 40,30, 33,052, 34,579 and 32,79. Finally, MDA levels were found as 5,239, 9,814, 6,695, 5,771 and 5,836. Briefly, POM and TAN showed their antioxidant functions by decreasing the levels of malondialdehyde (MDA), and protein carbonyl and increasing the activity of superoxide dismutase (SOD) and catalase (CAT). And also, these protective agents exhibited their anti-inflammatory functions by decreasing the content of TNF-α, IL-6, and IL-1β, and increasing the IL-10 levels.

Conclusion: Tangeretin and pomegrenate have a potential gastroprotective effect against ethanol-induced acute gastric ulcer and that the combined treatment is more beneficial than the effect of POM or TAN alone. In addition, this effect is thought to be due to the fact that both selected flavonoids can show a synergistic effect, reducing the levels of inflammation parameters and increasing antioxidant levels.
Comparison of the prevalence of sexual dysfunction in panic disorder patients in terms of gender
Authors: TÜNEL Munever
Published: September 2023

Purpose: The aim of this study is to evaluate the frequency of sexual dysfunction in male and female panic disorder (PD) patients and to make a comparison between genders.

Materials and Methods: A total of 57 cases, including 33 females aged 36±6 years and 24 males aged 35±7 years, who were sexually active, did not use psychotropic drugs, with primary diagnosis of PD according to DSM-5, were included in the study. Individual information collection forms and the Arizona Sexual Experiences Scale (ASEX) were applied to all cases, and sexual dysfunctions (SD) were questioned.

Results: According to the suggested cut-off score of the Turkish version of the Arizona Sexual Experiences Scale, 77.2% of all participants had SD. SD was detected in 81.8% of women and 70.8% of men. There was a significant difference between men and women in terms of ASEX total scores. There was no significant difference between men and women in terms of sexual desire and orgasm satisfaction. Sub-dimension scores of arousal, lubrication/erection, and reaching orgasm were significantly higher in females. Sexual reluctance was the most common in both genders, with 30.4% of women and 36.5% of men.

Conclusion: Sexual dysfunction is common among PD patients. Sexual reluctance is the most common in male and female patients with PD. Arousal and orgasm problems are more common in female PD patients than in male PD patients.
Evaluation of cardiac biomarkers, electrocardiogram changes and echocardiography findings before and after exercise in paediatric athletes
Authors: ÖZDEMİR DİLEK Semine , ERDEM Sevcan , K:URDAK Sanlı Sadi , ÖZBARLAS Nazan
Published: September 2023

Purpose: The aim of this study was to investigate the structural and electrical changes in the heart associated with exercise in young athletes under 18 years of age and to examine the relationship between these changes and biochemical markers.

Materials and Methods: In this study, 32 male paediatric athletes (five rowers, five kayakers and 22 footballers) were prospectively evaluated. Dynamic exercise training for 75 minutes was applied to all athletes. An echocardiographic evaluation was performed on the athletes at rest. An electrocardiogram (ECG) was taken before and after the exercise. Blood samples were taken from all athletes before the exercise, during the first hour of exercise and after the fourth hour of the training session to analyse the serum levels of creatine kinase myocardial band, troponin T(cTnT) and pro-brain natriuretic peptide.

Results: The mean age of all athletes was 15.3±0.9 years. In the echocardiography examination, end-diastolic thickness, left ventricular end-diastolic diameter, posterior wall end-diastolic diameter, left ventricular end-systolic diameter, left ventricular mass measurements (LVM) and left ventricular mass indices (LVMI) were higher among the rowers than in the remaining groups. In the post-exercise ECG, T-wave peaks were observed in 16 individuals, including all rowers, all kayakers, and six footballers. The cTnT values in the first hour and after the fourth were 0.31–0.71 ng/ml in football players, 0.10–0.27 ng/ml in rowers, and 0.04–0.15 ng/ml kayakers. An increase in cTnT levels was detected after the fourth hour of exercise in all groups. There was a correlation between T-wave peaks in the ECG taken after exercise and age, cTnT serum level and increased LVM.

Conclusion: In this study, we found T-wave peaks in half of the athletes after exercise. The serum cTnT levels of young athletes may be elevated by exercise and that LVM and LVMI may be higher in athletes. Echocardiography and ECG evaluations should be performed in paediatric athletes.
Evaluation of clinical and pathological responses of HER-2 positive locally advanced breast cancer patients after neoadjuvant therapy and surgery
Authors: BAYRAM Ertuğrul , METE Burak , KAHRAMANOĞLU Pakize İrem , MELEKOĞLU Ebru , TURKER Mehmet , KARA İ. Oğuz
Published: September 2023

Purpose: This study aimed to compare the effectiveness and toxicity of neoadjuvant dual Human epidermal growth factor receptor-2 (HER-2) blockade combined with chemotherapy in advanced breast cancer.

Materials and Methods: Patients with HER2-positive breast cancer who received trastuzumab (T)+ pertuzumab (P) with weekly neoadjuvant paclitaxel or docetaxel were included in the study. Patients’ age, clinical stage, histological reports, ki-67 index, toxicity profiles, and the state of the pathological and radiological response following neoadjuvant therapy were evaluated.

Results: All 40 patients were women (mean age 50.9) and the overall rate of pathological complete responses was 62.5% (25/40). The rates of non-responsive patients and grade 2 neuropathy were statistically significantly higher in the group receiving P+T+Weekly Paclitaxel. When SUV values were analyzed based on hormone positivity, it was found that they decreased dramatically in both groups and were statistically significant. The logistic regression analysis developed to predict the precise response status to therapy was found to be significant.

Conclusion: When comparing the agents used in dual HER-2 targeted therapies, patient response rates and toxicity profiles may differ. Ductal carcinoma in situ (DCIS) and molecular subtype were found to be significant variables in the developed logistic regression model.
The factors affecting survival in patients followed up with the diagnosis of lymphoma in the intensive care unit
Authors: AYDIN Kaniye , DOĞAN Ömer
Published: September 2023

Purpose: This retrospective analysis aimed to elucidate the key factors influencing survival outcomes in patients diagnosed with lymphoma and admitted to an Intensive Care Unit (ICU).

Materials and Methods: The study cohort comprised individuals aged 18 or older diagnosed with lymphoma and admitted to the ICU between November 2015 and February 2023. Data were collected on patients' demographic characteristics, primary hematological diagnoses, reasons for ICU admission, laboratory parameters, Acute Physiology and Chronic Health Evaluation (APACHE) II scores, Sequential Organ Failure Assessment (SOFA) scores, clinical trajectory, and 28-day mortality rates. Patients were stratified into two categories based on their mortality outcomes: Survivors and non-survivors.

Results: A total of 165 patients were included in the study, with a mean age of 52.41 ± 17.99 years; 63% were male. Table 1 summarizes the demographic characteristics, clinical trajectories, and 28-day mortality rates. The APACHE II and SOFA scores of the patients were 34 (7–53) and 12 (10–14), respectively. The predominant reasons for ICU admission were sepsis (58.2%) and acute respiratory failure (57.6%). Vasopressor necessity prior to and during ICU stay was 23.6% and 92.4%, respectively. During ICU monitoring, thrombocytopenia, and acute kidney injury (AKI) were observed in 77.6% and 66.4% of patients, respectively; 10% required renal replacement therapy. The 28-day mortality rate was 84.8%. Kaplan-Meier analysis revealed that patients with a SOFA score ≥ 9 had a significantly reduced survival time of 4.5 ± 0.4 days compared to those with lower SOFA scores (14.3 ± 2.6 days). Patients with AKI and those requiring invasive mechanical ventilation (IMV) exhibited reduced survival times of 4.7 ± 0.5 days and 5.6 ± 0.5 days, respectively. Elevated SOFA scores (HR 2.355, 95% CI 1.485–3.734), presence of AKI (HR 1.511, 95% CI 1.055–2.163), and the need for IMV (HR 5.721, 95% CI 1.377–23.770) were significantly correlated with increased 28-day mortality. Receiver Operating Characteristic (ROC) curve analysis identified the optimal SOFA cut-off point for predicting 28-day mortality as nine, with an Area Under the Curve (AUC) of 0.897, sensitivity 83.6% and specificity 92%.

Conclusions: The findings of this study underscore the elevated mortality rates among lymphoma patients admitted to the ICU. Our data suggest that several factors serve as significant predictors of 28-day mortality in this patient population. Specifically, elevated APACHE II scores, SOFA scores, the presence of AKI, and the requirement for IMV emerged as crucial indicators associated with adverse survival outcomes. Consequently, these factors warrant meticulous monitoring and could inform targeted interventions to improve survival rates among lymphoma patients in critical care settings.
Cilt Yaşlanmasında Prebiyotik ve Probiyotiklerin Rolü
Authors: KIROĞLU Olcay , GÜLLÜ Havanur
Published: September 2023

Cilt yaşlanması, ciltte ince çizgiler, kırışıklıklar, lekeler ve elastikiyet kaybı gibi belirtilerle karakterize edilen bir süreçtir. Bu süreç, birçok faktörün etkisi altında gerçekleşir, bunlar arasında yaş, güneş maruziyeti, genetik faktörler, sigara ve diyet alışkanlıkları yer alır. Son yıllarda, prebiyotikler ve probiyotiklerin cilt sağlığı ve yaşlanması üzerindeki etkisi giderek daha fazla araştırılmaktadır. Günümüzde cilt bakım ürünlerinde kullanılan bazı kimyasalların zararlı etkileri nedeniyle, doğal cilt bakım ürünleri giderek daha fazla ilgi görmektedir. Prebiyotik ve probiyotiklerin doğal yollarla cilt sağlığını desteklemesi, bu ürünlerin kullanımını daha cazip hale getirmektedir. Bu nedenle, cilt bakım endüstrisinde önemli bir pazar payına sahip olan prebiyotik ve probiyotik içeren ürünler, son yıllarda giderek daha popüler hale gelmektedir.

Prebiyotikler, bağırsaktaki yararlı bakterilerin büyümesini teşvik eden ve bağırsak sağlığını iyileştiren karbonhidrat bileşikleridir. Probiyotikler ise canlı mikroorganizmalar olarak tanımlanır ve insan sağlığına faydalı olan bakterileri kapsar.

Yapılan araştırmalar sonucunda, prebiyotiklerin cilt bariyerini güçlendirdiği, cilt iltihabını azalttığı ve antioksidan aktivitesi sayesinde serbest radikalleri nötralize ettiği belirlenmiştir. Bunun yanı sıra, probiyotiklerin de ciltteki mikrobiyal dengenin korunmasına yardımcı olduğu, cilt iltihabını azalttığı ve cilt bariyerinin onarımına katkı sağladığı gözlemlenmiştir. Ayrıca, bazı çalışmalarla prebiyotiklerin ve probiyotiklerin UV ışınlarının neden olduğu hasarı ve cilt yaşlanması belirtilerini azaltabileceği ortaya konmuştur.

Bu çalışmaların sonuçları, prebiyotiklerin ve probiyotiklerin cilt sağlığı ve yaşlanması üzerinde olumlu etkilerini desteklemektedir. Bu derleme, cilt mikrobiyomunun cilt yaşlanması üzerindeki etkisini ve buna ek olarak oral veya topikal uygulanan probiyotik ve prebiyotiklerin kozmetik sonuçlar üzerindeki etkilerini incelemektedir.
Assessment of Pain in Different Patient Populations
Authors: DEMİRTAŞ KARAOBA Dilan , TALU Burcu
Published: September 2023

Pain is an experience that negatively affects a person's life. When choosing the intervention strategies to be planned for the treatment of pain, an accurate assessment of the patient's level of pain is crucial. Asking the patient if they are in pain is the simplest way to determine their level of pain. However, a simple "yes or no" assessment is insufficient. To assess pain, both single-dimensional and multidimensional scales are employed nowadays. In this article, due to the subjectivity and individuality of pain; Information about commonly used pain scales developed specifically for certain patient populations will be given.
Kripto Paraların Çevre Kirliliği, Makroekonomik Göstergeler ve Suç Üzerindeki Etkileri
Authors: KAVAS Yusuf Bahadır
Published: September 2023

Bu makale kripto paraların oluşturduğu çevresel etkileri, makroekonomik ilişkileri ve suç üzerindeki unsurları ortaya çıkarmayı hedeflemektedir. Kripto para madenciliği için gerekli olan enerjinin zamanla çevre kirliliğine daha da fazla sebep olduğu ve iklime daha fazla zarar verdiği; kripto paraların çevresel ayak izlerinin dünyanın geleceği için tehlikeli bir noktaya ulaşabileceği düşünülmektedir. Madencilik esnasında daha az enerjiye ihtiyaç duyulan farklı sistemlerin geliştirilebileceği, yenilenebilir enerji kaynaklarından elde edilen enerjinin, kamu enerji tüketiminin düşük olduğu saatlerde kripto madencilik sistemi için açılabileceği göz önünde bulundurulmalıdır. Ekonomiler üzerindeki olumsuz etkilerini azaltmak için kripto paralar üretilirken denetlenebilecek, vergi kaybının önüne geçilebilecek ve tüketici/yatırımcı ihtiyaçlarına hitap edebilecek bir yaklaşımla hareket edilmesi gerekmektedir. Devletlerin etkili bir yasal düzenlemesinin olmaması nedeniyle kripto paralar kara para aklama, uyuşturucu-silah-insan kaçakçılığının ve terör eylemlerinin finansmanı için kullanılabilmektedir. Bu nedenle tüm ülkelerin süratle kripto paralar ile ilgili yasal mevzuatlarını oluşturmaları ve karaborsa işlemlerini yasaklamaları, küresel Bitcoin (BTC) denetimini düzenlenmeleri elzemdir.
A Baker's Dozen Significant Books about Rural Crime in the Twenty-First Century
Authors: Donnermeyer Joseph F.
Published: September 2023

Most of us have heard of and likely voiced the phrase a ‘baker’s dozen’ to refer to adding an extra item to a group of twelve to make sure there are enough. This review essay will abide by this centuries-old tradition, however, out of a necessity rather than incarceration. There are now enough monographs and edited books about rural crime and criminal justice topics that selecting a trim ten, a lissome eleven or a svelte dozen is impossible. Yet, even with 13, as the reader of this review essay will discover, there are plenty more books that could easily qualify for the list. To show no disrespect for those tomes not mentioned in the main text of this highly personalized version (or perhaps, highly biased rendition is the more accurate phrase) of a baker’s dozen, the essay will conclude with a brief mention of the others.
Policing Rural Crimes and Rural Communities in England
Authors: Bullock Karen , Garland Jon
Published: September 2023

This article examines factors that influence the processes and practices of crime prevention and investigation in rural areas of England. Whilst evidence shows that rural crime is a significant problem, there has been hitherto a dearth of research into how the issue is policed. Drawing on the perspectives of police personnel, this article examines the features of the rural environment and the organisation and management of police services that influence the delivery of police work in rural areas of England. Specifically, the article considers factors that influence the reporting and subsequent recording of rural crimes; how police officers understand and perceive rural crimes; how police services prioritise crimes for preventative and investigative purposes; how responsibility for investigating rural crimes is diffused across law enforcement agencies and how this can cause confusion for officers; matters related to the generation of evidence; officer understanding of the legislation regarding rural crime; the willingness of officers to undertake the investigation of rural crimes and the reluctance of some to live in the countryside; and the organisation and management of police resources in rural areas. In so doing, it sets out the reasons why the policing of rural spaces is distinctive and considers implications for police work and its outcomes.
Editor’s Introduction to Volume 8, Issue 1
Authors: Donnermeyer Joseph F. , Harkness Alistair , Peterson Jessica René
Published: September 2023

No abstract available.
EVALUATION OF AN HPHT UNIT COUPLED WITH NIR PROBE TO DETERMINE ASPHALTENES PRECIPITATION ONSET UNDER DIFFERENT PRESSURES
Authors: Rezende da Silva Daniel , Dias Capuchinho João Pedro , Domingos da Silva Edilson , Hartmann Daniela , Khalil de Oliveira Marcia Cristina , Fernandes Lucas Elizabete
Published: September 2023

Asphaltenes are characterized as the crude oil fraction with the highest molar mass and polarity, presetting mainly (poly) aromatic groups. The flocculation and deposition of asphaltenes causes large losses to the oil industry. Understanding the phase behavior of asphaltenes under conditions closer to those found in reservoirs is important. Therefore, LMCP/UFRJ started operating a high-pressure high-temperature (HPHT) unit coupled to a near-infrared spectrometer probe that can use different flocculants. This work describes the development of a procedure as well as the validation of the results obtained from this unit. Due to the complex composition of crude oil, model systems (MS) were prepared with asphaltenes extracted with n-pentane (C5I) and n-heptane (C7I). The experiments were carried out at atmospheric pressure, titrated with n-heptane, and at 100 and 300 bar titrated with propane. As expected, C7I asphaltenes were more unstable, presenting lower precipitation onset than C5I asphaltenes under ambient conditions and higher pressures. However, for both MS, the stability increased with rising pressure when using propane as a solvent. The proposed method to evaluate asphaltenes precipitation onset was effective for MS in toluene and dead crude oil, and is a promising alternative for investigation of different types of crude oil.
Catalizadores sulfurados CoMo soportados sobre hidrotalcitas terciarias calcinadas (MeFeAl, Me2+: Co2+, Ni2+, Mg2+ y Zn2+) para ser usados en la reacción de hidrodesulfuración de dibenzotiofeno
Authors: Oviedo Edwin , Linares Carlos F. , Brune Sylvette
Published: September 2023

Se sintetizaron cinco hidrotalcitas terciarias conteniendo dos cationes trivalentes: Fe3+ y Al3+, y un catión divalente Mg2+, Co2+, Ni2+ o Zn2+. Se mantuvo una proporción molar [M+3/(M3++M2+)] de 0,22 y una proporción molar de [Fe3+/Al3+] de 0,66; con la excepción de la hidrotalcita MgFeAl cuya proporción fue duplicada a 1,32. Los óxidos de estas hidrotalcitas fueron usados como soportes de la fase activa (Mo) promovida con Co. Hidrotalcitas, óxidos mixtos y sus precursores catalíticos fueron caracterizados por las técnicas de: análisis químico por fluorescencia de rayos X, medidas de superficie, difracción de rayos (DRX), desorción a temperatura programada (TPD-CO2), análisis elemental (C y S) y microscopía electrónica de transmisión de alta resolución. Todos los precursores catalíticos fueron probados en la reacción de hidrodesulfuración de dibenzotiofeno mostrando el siguiente orden de actividad: CoMo/γAl2O3 > CoMo/MgFeAl(0,66)> CoMo/MgFeAl(1,32)> CoMo/CoFeAl> CoMo/NiFeAl> CoMo/ZnFeAl. La actividad catalítica y la selectividad hacia la formación de productos de hidrogenación con respecto a la desulfuración directa (HID/DSD) se incrementó a medida que se incrementó la basicidad del catalizador. Estos resultados fueron asociados con la fracción de Mo (fMo) y la naturaleza del soporte. Es importante mencionar que los catalizadores: CoMo/MgFeAl(0,66) y CoMo/MgFeAl(1,32) mostraron la más alta selectividad hacia la ruta de hidrogenación comparado con el catalizador de referencia (CoMo/γ- Al2O3). Adicionalmente, la actividad del catalizador CoMo/MgFeAL(0,66) hacia la ruta de HID fue la más alta, inclusive superando la actividad del CoMo/γ-Al2O3.
Is the Rothbardian Theory of Punishment Retributive?
Authors: Dominiak Łukasz
Published: September 2023

Murray Rothbard claims that it is “evident that our theory of proportional punishment—that people may be punished by losing their rights to the extent that they have invaded the rights of others—is frankly a retributive theory of punishment, a ‘tooth (or two teeth) for a tooth’ theory.” The present paper argues that it is not. The role that Rothbard assigns for victims in determining punishment justifies classifying his theory of punishment as corrective rather than retributive, for vesting victims with rights over punishment defeats the retributive justice requirement that criminals are punished solely because they deserve it and in accordance with their respective deserts. Instead of giving offenders what they objectively deserve, the Rothbardian theory of punishment allows victims to seek compensation in various forms, including revenge.
Obraz dawnego powiatu zbaraskiego na podstawie nazw miejscowości
Authors: Czapla Anna
Published: September 2023

Powiat zbaraski wraz z zachodnią częścią Podola przyłączono do Polski jeszcze w XIV w., do której z przerwami przynależał do końca II wojny światowej. Celem artykułu jest semantyczna i strukturalna analiza nazw miejscowości z tego terenu, na podstawie której wyłania się językowy obraz powiatu zbaraskiego. Najliczniejsza grupa nazw fizjograficznych opisuje jego właściwości naturalne – bogactwo rzek i jezior, występujące na tym terenie zwierzęta, miejsca zalesione, liczne krzywizny i wysoczyzny. Również nazwy etniczne pośrednio odnoszą się do charakteru samej krainy. Natomiast nazwy kulturowe opisują powiat ze względu na jego właściwości nabyte w wyniku działalności człowieka. Najmłodszą warstwę tychże stanowią nazwy ideologiczne powstałe w czasach komunizmu. Starsze nazwy kulturowe informują o formach osadniczych, miejscach o charakterze obronnym, miejscach związanych z gospodarką. Zależne od przybywania osad w powiecie są nazwy ponowione oraz nazwy deminutywne. Wśród nazw odosobowych najliczniejszą grupę stanowią nazwy patronimiczne, mające za podstawy imiona wschodnie lub neutralne, podobnie zresztą jak dzierżawcze.