bluuebunny/crossref_metadata_2025 huggingface dataset:
Kafka et la vengeance du sergent Hoff
Authors: Le Bihan Adrien
Published: December 2021

Dans les notes consécutives à son bref séjour en France de 1911, Kafka consacre deux lignes au sergent Hoff devenu célèbre durant le siège de Paris de 1870 pour avoir vengé son père en tuant des Prussiens. Son résumé tronqué laissant croire à une supercherie, il convient de démêler dans son œuvre les motifs secrets de cette altération.
L’accueil familial thérapeutique : soigner ou prendre soin ?
Authors: Tavares Manuel , Agron Mathilde , Gaillot Naima , Godin Carole , Lemaigre Sandra , Richard Karine , Rodenschmit Alexandra
Published: December 2021

Les auteurs exposent la particularité de l’accueil familial thérapeutique de leur service de pédopsychiatrie. Après avoir décrit le dispositif de cet accueil et en particulier sa règle fondamentale, les auteurs présentent trois vignettes cliniques qui mettent en évidence l’importance de la préparation à l’accueil, de la construction des liens et de l’élaboration de l’arrêt.
Insects in Atlantic salmon (Salmo salar) diets – comparison between full-fat, defatted, and de-chitinised meals, and oil and exoskeleton fractions
Authors: Weththasinghe P. , Hansen J.Ø. , Rawski M. , Józefiak D. , Ghimire S. , Øverland M.
Published: December 2021

The present study investigated the effect of meals and fractions of black soldier fly larvae (BSFL; Hermetia illucens) in diets for Atlantic salmon (Salmo salar) on the physical quality of feed pellets, nutrient utilisation, and growth performance. Six extruded diets were produced: control diet (CD); full-fat BSFL meal diet (IM); defatted BSFL meal diet (DFIM); de-chitinised BSFL meal diet (DCIM); BSFL oil diet (IO) and BSFL exoskeleton diet (EX). The full-fat, defatted and de-chitinised meals replaced 15% of protein in the control diet. An eight-week study was conducted using salmon with average 28 g initial weight. The full-fat and de-chitinised meals in the diets numerically reduced pellet hardness, expansion, and water stability. The full-fat and de-chitinised meals improved growth rate of salmon, whilst defatted meal, oil and exoskeleton supported similar growth performance as the control. Feed intake and growth rate of fish fed full-fat meal diet were higher than those fed the other insect diets, but defatted meal gave a better feed conversion ratio than full-fat meal. Defatted meal, de-chitinised meal and exoskeleton reduced protein digestibility in fish, however; defatted meal increased the digested protein retention. In conclusion, use of full-fat BSFL meal improved feed intake and growth rate of salmon when replacing 15% of dietary protein. The present results suggest that less processed fullfat form of BSFL is more optimal in diets for salmon and further processing to remove lipid or exoskeleton fractions would only lead to an additional cost.
A new approach to the inverse discrete transmission eigenvalue problem
Authors: Bondarenko Natalia P. , Yurko Vjacheslav A.
Published: December 2021

A discrete analog is considered for the inverse transmission eigenvalue problem, having applications in acoustics. We provide a well-posed inverse problem statement, develop a constructive procedure for solving this problem, prove uniqueness of solution, global solvability, local solvability, and stability. Our approach is based on the reduction of the discrete transmission eigenvalue problem to a linear system with polynomials of the spectral parameter in the boundary condition.
A regularity criterion for liquid crystal flows in terms of the component of velocity and the horizontal derivative components of orientation field
Authors: Li Qiang ,   School of Mathematics and Statistics, Xinyang College, Henan 464000, China, Yuan Baoquan ,   School of Mathematics and Information Science, Henan Polytechnic University, Henan 454000, China
Published: December 2021

In this paper, we establish a regularity criterion for the 3D nematic liquid crystal flows. More precisely, we prove that the local smooth solution $ (u, d) $ is regular provided that velocity component $ u_{3} $, vorticity component $ \omega_{3} $ and the horizontal derivative components of the orientation field $ \nabla_{h}d $ satisfy

   \begin{document}$ \begin{eqnarray*} \int_{0}^{T}|| u_{3}||_{L^{p}}^{\frac{2p}{p-3}}+||\omega_{3}||_{L^{q}}^{\frac{2q}{2q-3}}+||\nabla_{h} d||_{L^{a}}^{\frac{2a}{a-3}} \mbox{d} t<\infty,\nonumber \\ with\ \ 3< p\leq\infty,\ \frac{3}{2}< q\leq\infty,\ 3< a\leq\infty. \end{eqnarray*} $\end{document}
Relative mispricing and takeover likelihood
Authors: Li Keming ,   Department of Accounting and Finance, Texas A & M University, San Antonio, America
Published: December 2021

This paper examines the effect of acquirer likelihood on future stock returns. In sharp contrast to prior findings, acquirer likelihood is a strong and negative predictor of cross-sectional future returns after controlling for target likelihood. If takeover exposure represents a risk premium, the effect on stock valuation should only present in either likelihood measure (acquirer or target likelihood). This evidence casts doubt on the rational risk explanation, but is consistent with a relative mispricing story. Investors take positions accordingly to explore profits from takeovers. Profits from trading strategy based on takeover probability are concentrated in stocks with high misvaluation characteristics, including small size, value, high momentum, high investment, and low turnover firms, as well as both high and low issuance (or accrual) firms.
Revisión estratigráfica del Sinemuriense-Pliensbachiense inferior de Mallorca
Authors: Sevillano Ana , Rosales Idoia , Barnolas Antonio , Bádenas Beatriz , López-García José María
Published: December 2021

Los nuevos resultados obtenidos en estudios recientes del Sinemuriense-Pliensbachiense inferior (Formación Sóller) en la isla de Mallorca, aconsejan modificar su esquema litoestratigráfico. La nueva propuesta litoestratigráfica para este intervalo elimina la Formación Sóller y eleva sus tres miembros, anteriormente definidos como miembros Es Barraca, Sa Moleta y Es Racó, a la categoría de formación. Esta redefinición se apoya en los nuevos datos estratigráficos, sedimentológicos y bioestratigráficos obtenidos a partir del estudio detallado de la Formación Es Barraca (término recuperado en este artículo), que indican que los miembros de la hasta ahora Formación Sóller no son equivalentes laterales entre sí y representan distintas etapas en la evolución de la cuenca, estando separadas por discontinuidades de carácter regional. La primera unidad (Formación Es Barraca) representa la evolución durante el Sinemuriense de una plataforma carbonatada somera, similar a las plataformas epicontinentales desarrolladas durante el Lías inferior en el ámbito del Tethys más occidental. La segunda y la tercera (Formación Sa Moleta y Formación Es Racó; Pliensbachiense inferior) son unidades disconformes con la anterior, muestran litologías y asociaciones de facies diferenciadas y presentan una distribución y espesores irregulares a favor de surcos intraplataforma.
Le secrétariat d’État à l’aviation de Vichy et la collaboration dans l’industrie aéronautique
Authors: d’Abzac-Epezy Claude
Published: December 2021

De 1940 à 1944, l’industrie aéronautique française a produit 4 142 avions et 12 456 moteurs. Les ventes de matériel aéronautique représentent ainsi la moitié du total des ventes d’armement de la France au III Reich. Cette étude se propose de montrer le rôle du secrétariat d’État à l’aviation dans la mise sur pied de la collaboration aéronautique entre la France et l’Allemagne nazie. Comment il s’est imposé dans une négociation qui n’était pas initialement de son ressort et les raisons pour lesquelles il a tenté d’imposer une collaboration d’État, au lieu d’arrangements privés entre firmes
Antonio Rossellino, un atelier et des matériaux
Authors: Guillet Séverine
Published: December 2021

Cet article part d’un constat : le nombre impressionnant de reliefs en stuc issus de l’atelier d’Antonio Rossellino. L’étude de ce corpus apporte de précieuses informations sur l’organisation d’un grand atelier florentin de la Renaissance. Ce sont tout d’abord les moyens et les objectifs de l’atelier qui peuvent être analysés face à la quantité et à l’hétérogénéité des œuvres. Les différentes compositions permettent de mieux cerner la place des apprentis, et les relations qu’entretenaient les ateliers de sculpteurs et de peintres sont éclairées par l’étude des polychromies. La diffusion géographique du corpus confirme d’intéressantes hypothèses sur la pluralité des lieux de l’atelier. Enfin, les particularités du stuc et la confrontation du corpus avec d’autres œuvres d’Antonio Rossellino permettent quelques clarifications sur la façon dont les différents matériaux étaient perçus et employés dans l’Italie du Quattrocento.
Couleurs, matériel et matière : aperçu scientifique de la polychromie de reliefs en stuc italiens de la Renaissance
Authors: Le Hô Anne-Solenn , Pingaud Nathalie , Vandenberghe Yannick
Published: December 2021

Le stuc est un matériau abondamment utilisé par les sculpteurs italiens de la Renaissance pour produire et diffuser à grande échelle leurs œuvres, principalement par moulage et estampage de modèles en marbre ou en terre. Les ateliers de Lorenzo Ghiberti, de Donatello, d’Antonio Rossellino et de Desiderio da Settignano, entre autres, contribuèrent à diffuser en Italie des séries de reliefs en stuc. Le thème de la Vierge et l’Enfant, traité en relief, constitue sans conteste le sujet le plus représenté à Florence au xve siècle. Ces oeuvres sont généralement peintes et dorées. Étant un élément essentiel de l’œuvre au même titre que e relief lui-même, la polychromie illustre ainsi les goûts et/ou le niveau social des commanditaires.Dans cette contribution, nous interrogeons le lien entre matériau support et polychromie d’un ensemble de stucs florentins ayant pour sujet la Vierge et l’Enfant, dont il existe de nombreuses répliques et variantes dans les collections publiques françaises. Nous présentons les données collectées par des observations et des analyses multi-échelles sur la mise en peinture de ces reliefs, soigneusement et largement polychromés, enrichis de dorures et de décors (poinçons, pastilles en relief, glacis et motifs surpeints). Le choix des matériaux de la couleur, les séquences de leur mise en œuvre et les techniques de décor caractérisés mettent en évidence les savoir-faire des peintres italiens et la correspondance de certains décors entre peinture et sculpture. Nous nous attachons également à mieux comprendre les évolutions au cours du temps de ces œuvres, souvent repeintes, ou ayant subi une altération des couleurs, influençant leur perception actuelle.
Religiosidade e enfrentamento religioso e espiritual de idosos participantes de um centro de convivência/ Religiosity and religious and spiritual coping of elderly participants in a conversion center
Authors: Alves dos Santos Leide Daiana , Gomes Martins Priscila , Rosa dos Santos Thatyane , Ferreira Ramalho Mariana , Sadoyama Leal Geraldo , Pilger Caliope
Published: December 2021

Objetivo: Avaliar a religiosidade, o enfrentamento religioso e espiritual dos idosos que participam de um centro de convivência para terceira idade. Método: Estudo descritivo, exploratório, com abordagem quantitativa. Foram entrevistados 110 idosos. Os questionários utilizados para a coleta dos dados foram: instrumento de caracterização sociodemográfico e religioso, Mini Exame do Estado Mental (MEEM), Índice de Religiosidade de Duke e a Escala de Coping Religioso e Espiritual Abreviada (CRE abreviada). Utilizou-se da estatística descritiva, Coeficiente de Correlação de Pearson e Spearman para análise dos dados. Resultados: Maioria do sexo feminino (61,8 %), faixa etária de 60 a 69 anos (54,5%), etnia branca (47,3%), e predomínio de viúvos (36,4%). A religião de maior porcentagem foi a católica (68,2%). Evidenciou-se correlação positiva, com nível de significância, ao avaliar Religiosidade Organizacional e Coping Religioso Espiritual (CRE) Positivo (p=0,000), Religiosidade Não Organizacional com (CRE) Positivo e Negativo (p=0,010, p=0,047, respectivamente), Religiosidade Intrínseca e (CRE) Positivo e Total (p= 0,000, p=0,002, respectivamente). Conclusão: Percebeu-se que os idosos utilizam de estratégias religiosas e espirituais para lidar com situações estressantes; e que a religiosidade está presente em suas vidas atuando de forma positiva.
Satisfação do usuário com os serviços de saúde de atenção básica: percepção masculina
Authors: Pavan Isabella Pereira , Baptista Angeline da Silva Lopes , Rosa Caio Pupin , Cabral Danusa da Silva , Bittencourt Flávio , Silva Simone Albino
Published: December 2021

Objetivo: avaliar a satisfação do usuário do sexo masculino com os serviços oferecidos na atenção primária à saúde. Método: estudo descritivo, transversal, realizado em unidades da Estratégia de Saúde da Família por meio de entrevista com 104 homens, utilizando questionário social e instrumento validado. Na análise, utilizou-se o teste Exato de Fisher, considerando a significância de 5%. Resultado: o perfil predominante foi de homens brancos, heterossexuais, casados, com idade entre 50 e 59 anos, com emprego fixo, renda mensal entre um e dois salários mínimos e que não concluíram o ensino fundamental. Os maiores percentuais de satisfação foram com a cordialidade, o exame clínico e a atenção dada às queixas pelo médico/enfermeiro. O tempo em sala de espera, o acesso e o agendamento da consulta apresentaram os menores percentuais de satisfação. Usuários com ensino médio incompleto apresentaram avaliação mais positiva em relação à consulta, cordialidade do profissional e o tempo na sala de espera (p<0,05). Por sua vez, as explicações recebidas em consulta geraram mais insatisfação entre sujeitos que utilizam o serviço anualmente. Conclusão: os homens participantes do estudo estão mais insatisfeitos com a organização dos serviços de saúde do que com o atendimento dos profissionais.
 Autocuidado de pessoas com diabetes mellitus: reuso e descarte de seringas e agulhas / Self-care of people with mellitus diabetes: reuse and disposal of syringes and needles
Authors: Carneiro Cunha Neves Heliny , Faria Alves Favorito Ana Caroliny , Pagotto Valéria , De Lima Vieira dos Santos Silvana
Published: December 2021

Objetivo: Analisar a taxa de reuso de seringas e agulhas e identificar as práticas de descarte de perfurocortantes por usuários de insulina. Método: Estudo transversal, realizado com pessoas diagnosticadas com diabetes mellitus tipo II de um Centro de Referência em Diagnóstico e Terapêutica da região Centro-Oeste do Brasil. Foram utilizados dados secundários provenientes de prontuários e fichas de consulta. As diferenças de proporção foram estimadas pelo teste qui-quadrado, considerando-se p<0,05. Resultados: A taxa de reuso de seringas e agulhas foi de 94,9%. Houve alta prevalência do reuso de seringas e agulhas por mulheres, com mais de 60 anos, com tempo de estudo menor do que cinco anos, que possuíam mais de 11 anos de diagnóstico. A maioria dos usuários descartou as agulhas e seringas no lixo domiciliar. Tais dados evidenciam que as práticas de autocuidado realizadas pelas pessoas com DM quanto ao reuso e descarte de perfurocortantes não são seguras e podem favorecer complicações. Conclusão: Apesar das características demográficas e clínicas não terem apresentado associação com o reuso, esforços devem ser direcionados para as práticas de educação em saúde, levando em consideração o contexto da pessoa, a condição socioeconômica, nível de escolaridade e seu papel ativo no seguimento do tratamento.
Tempo para o diagnóstico da hanseníase e sua relação com fatores sociodemográficos e clínicos/Time for leprosy diagnosis and its relation to sociodemographic and clinical factors
Authors: Marciano de Araujo Ferreira Natalia , Kiyomi Furuya Rejane , Maia Storer Jessica , Vieira Ramos Antônio Carlos , De Almeida Crispim Juliane , Alexandre Arcêncio Ricardo , Meneguetti Pieri Flávia
Published: December 2021

Objetivo: investigar os fatores associados ao tempo decorrido entre a identificação dos sinais e sintomas relacionados à hanseníase até o diagnóstico dos casos atendidos na atenção primária à saúde. Método:estudo transversal e analítico, realizado na atenção primária à saúde em um município de grande porte localizado no sul do Brasil, com amostra de 245 indivíduos. O período analisado foi de 2009 a 2016, por meio das fichas de notificação e consulta ao prontuário. Para análise do tempo para o diagnóstico de hanseníase (categorizado em 0 a 5 anos ou 6 anos ou mais), conduziram-se análises de frequência relativa simples, bivariada e regressão logística binária aferida pelo OddsRatio (OR) e intervalo de confiança de 95%. Nível de significância estatística estabelecido de 5% para todas as análises. Resultados: o tempo para o diagnóstico variou de 1 mês a 20 anos, sendo necessários, em média, 7,9 consultas e 4,6 anos para obtê-lo. Ter três ou mais hipóteses aumentou a chance de diagnóstico tardio, comparado ao oportuno (OR ajustado=4,82; IC95%: 2,13-10,89; P<0,001). Conclusão:o tempo decorrido para o diagnóstico teve impacto nas características da hanseníase, sendo que quanto maior o número de hipóteses apresentadas, maior o tempo decorrido para o diagnóstico e, consequentemente, maiores as chances de apresentar GIF instalado.
Significados atribuídos por adolescentes a uma intervencao educativa sobre hanseníase<
Authors: Hinnah Borges Martins de Freitas Bruna , Silva Fabiane Blanco , Dias dos Santos Silva Hellen Cristina , Ferreira da Silva Karine , Edvirges Garcia Silva Sabrina , Munhoz Gaíva Maria Aparecida
Published: December 2021

Objetivo: descrever o significado atribuído por adolescentes a uma intervenção educativa sobre hanseníase mediada por jogos. Método: trata-se de uma pesquisa exploratória, de abordagem qualitativa, realizada com 30 adolescentes de uma escola pública de Cuiabá, Mato Grosso, Brasil. Aplicou-se uma intervenção de enfermagem com jogos adaptados à temática. Os dados foram coletados por meio de gravações cujas falas dos participantes durante a última etapa da intervenção educativa foram transcritas e analisadas segundo a técnica de análise de conteúdo temática. Resultados: os adolescentes expressaram alegria e satisfação por participarem da intervenção. Os elementos trazidos em suas falas enfatizam o aprendizado sobre os aspectos gerais da hanseníase adquirido dos jogos e a possibilidade de atuarem como agentes transformadores da realidade perante a hanseníase. Conclusão: tal intervenção demonstrou potencial para a construção coletiva de saberes sobre a hanseníase com vistas à desmistificação dos falsos conceitos e mitos atribuídos ao agravo. Espera-se que a partir deste estudo a intervenção possa ser aplicada em diferentes contextos com vistas à promoção da saúde e prevenção da hanseníase.
Desfecho clínico de pacientes em urgência dialítica:
Authors: Gomes Yury , Carneiro Remo Rodrigues , Boução Daniela Maria Nantes , Moreira Lisiany Carneiro de Santana , Sena Emily Manuelli Mendonça , Oliveira Letícia Lima
Published: December 2021

Objetivo: Investigar o desfecho clínico de pacientes em urgência dialítica submetidos à terapia renal substitutiva, por meio de uma revisão integrativa da literatura.
Método: Revisão integrativa da literatura de estudos publicados de janeiro de 2010 a julho de 2020, na íntegra, em inglês e português, nas bases de dados: Literatura Latino Americana e do Caribe em Ciência da Saúde, Medical Literature Analysis and Retrieval System Online, Base de dados de Enfermagem e PUBMED. Foram utilizadas palavras-chave e descritores: “hemodiálise”, “emergência”, “diálise renal”, “mortalidade, “desfecho clínico” e “urgência dialítica”. Os textos foram pré-selecionados a partir da leitura dos títulos e resumos, verificando sua aderência ao tema, encontrando-se 344 artigos. A seguir, foi realizada a leitura dos resultados e considerações dos estudos. Dos 334 artigos pré-selecionados, apenas 13foram incluídos. Resultados: Há recorrência da urgência dialítica, sendo o óbito o principal desfecho clínico.
Conclusão: Os estudos acerca dos desfechos clínicos de pacientes em urgência dialítica ainda são poucos se comparado à dimensão que a doença renal possui na população mundial. Conhecer esses desfechos dará subsídios para novos estudos sobre a sobrevida desses pacientes e para políticas de saúde mais eficazes.
Infecção relacionada à assistência à saúde e sepse na hospitalização em pediatria
Authors: Silva Yngrid Fernandes , Tacla Mauren Teresa Grubisich Mendes , Costa Dayanne Cristina Zanfrille da , Kerbauy Gilselena , Mendes Patrícia Basso Squarça
Published: December 2021

Introdução: As infecções em pediatria são entraves no tratamento da criança hospitalizada, pois amplificam a morbidade e mortalidade, o tempo de permanência hospitalar, os custos e o sofrimento do paciente e sua família. Objetivo: investigar a frequência das infecções relacionadas à assistência à saúde e sepse em crianças hospitalizadas. Método: Trata-se de um estudo quantitativo, prospectivo e analítico. Os dados clínico-epidemiológicos foram obtidos por meio de 173 prontuários físicos e os resultados das culturas e antibiogramas foram coletados nos respectivos prontuários eletrônicos dos pacientes. Os dados foram analisados via Microsoft Office Excel® e análise descritiva. Resultados: Identificou-se uma alta prevalência de infecções relacionadas à assistência à saúde com 31% (n= 54) e destas 55% desenvolveram sepse (n= 32). Conclusão: Os achados permitem uma reflexão das práticas assistenciais executadas, bem como medidas que podem ser adotadas para sua melhoria, visando a diminuição dos índices de infecção dentro dos serviços de saúde com ênfase na população pediátrica.
The Impact of Matrix Cross-Linking Degree on Chemo-Resistive Properties of Natural Rubber-Carbon Nanostructure Composite
Authors: Stepina Santa , Klemenoks Igors , Sakale Gita , Knite Maris
Published: December 2021

The aim of this work is to investigate chemo-resistivity properties of natural rubber-carbon nanostructure composite, that’s why a change of diffusion characteristics and reversibility of electro-chemical properties of the composite with different degree values of crosslinks have been analysed. The composites are made from natural rubber (polyisoprene) as matrix material and high structure carbon black as electro-conductive filler. In order to investigate diffusion characteristics of volatile organic compounds (VOC) in relation to chemo-resistive response of composites simultaneous mass, length and electrical resistance change measurements of the samples, when samples are held in VOC and after exposures to VOC were carried out. Electrical resistance increase mechanism in the composite advances with the composite structure development during vulcanization.
Intrinsic Diffusivities Ratio Analysis in Double Multiphase Systems
Authors: Yarmolenko Mykhaylo V.
Published: December 2021

Our investigations show that electrochemical corrosion of copper is faster than electrochemical corrosion of aluminium at temperatures below 100°C. Literature data analysis shows that the Al atoms diffuse faster than the Cu atoms at temperatures higher than 475°C, Al rich intermetallic compounds (IMCs) are formed faster in the Cu-Al system, and the Kirkendall plane shifts toward the Al side. Electrochemical corrosion occurs due to electric current and due to diffusion. An electronic devise working time, for example, depends on initial copper cover thickness on aluminium wire, connected to the electronic devise, temperature, and volume and dislocation pipe diffusion coefficients, so copper, iron, and aluminium electrochemical corrosion rates are investigated experimentally at room temperature and at temperature 100°C. Intrinsic diffusivities ratios of copper and aluminium at different temperatures and diffusion activation energies in the Cu-Al system are calculated by proposed here methods using literature experimental data. Dislocation pipe and volume diffusion activation energies of pure iron are calculated separately by earlier proposed method using literature experimental data. Aluminium dissolved into NaCl solution as the Al3+ ions at room temperature and at temperature 100°C, iron dissolved into NaCl solution as the Fe2+ (not Fe3+) ions at room temperature and at temperature 100°C, copper dissolved into NaCl solution as the Cu+ ions at room temperature and as the Cu+ and the Cu2+ ions at temperature 100°C. It is found experimentally that copper corrosion is higher than aluminium corrosion, and ratio of electrochemical corrosion rates, kCu/kAl>1, decreases with temperature increasing, although iron electrochemical corrosion rate does not depend on temperature below 100°C. It is obvious, because the melting point of iron is more higher than the melting point of copper or aluminium. It is calculated that the copper electrochemical corrosion rate is approximately equal to aluminium electrochemical corrosion at temperature about 300°C, so copper can dissolve into NaCl solution mostly as the Cu2+ ions at temperature about 300°C. The ratio of intrinsic diffusivities, DCu/DAl<1, increases with temperature increasing, and the intrinsic diffusivity of aluminium could be approximately equal to the intrinsic diffusivity of copper at temperature about 460oC. Intrinsic diffusivities ratios in the Cu-Zn system at temperature 400°C and in the Cu-Sn system at temperatures from 190°C to 250°C are analyzed theoretically using literature experimental data. Diffusion activation energies and pre-exponential coefficients for the Cu-Sn system are calculated combining literature experimental results.
Prediction of Structural and Magnetic Properties of Nanocrystalline Mechanically Alloyed Fe-Ni Powders Using Multi-Gene Genetic Programming Approach
Authors: Mamar Bouziane , Said Bergheul , Rachid Renane
Published: December 2021

In this paper, a theoretical model based on multi-gene genetic programming (MGGP) approach has been applied to predict the structural and magnetic properties in nanocrystalline Fe–Ni powders prepared by mechanical alloying (MA) using a planetary ball mill. The MGGP model was used to correlate the input parameters (milling speed, chemical composition, and milling time), to output parameters (crystallite size and coercivity) of nanocrystalline Fe–Ni powders. The model obtained was tested with additional data to demonstrate its performance and prediction ability. The MGGP model is a robust and efficient method to find an accurate mathematical relationship between input and output data. A sensitivity analysis study was applied to determine the most influential milling parameters on the crystallite size and coercivity.
Dynamics and Geometry Effects on the Capillary Flows in Porous Media for Enhanced Oil Recovery
Authors: Soleimani Hassan , Ali Hassan , Yahya Noorhana , Khodapanah Leila , Sabet Maziyar , Demira Birol M.R. , Kozlowski Gregory
Published: December 2021

The continuing depletion of light oil supplies and the rapidly growing demand for energy are forcing oil and gas companies to explore unconventional oil extraction techniques. The structure and flow rate implies an impact on the trapping and mobilization of oil in the reservoir. This article studies the effect of pore geometry and dynamics on water-oil displacement as a two-phase flow system. The pore geometries of sandstone were extracted using the non-destructive 3D micro computational tomography (micro-CT) technique. Two-phase flow simulations were performed using COMSOL Multiphysics on the micro-CT images to show the effect of the capillary number and the flow pattern. Velocity and relative permeability of the non-wetting phase at different points of the porous structure was computed. The effect of viscosity of wetting fluid on the pore structure was also studied to evaluate the parameters affecting enhanced oil recovery (EOR).
A Genetic Variation of Lipopolysaccharide Binding Protein Affects the Inflammatory Response and Is Associated with Improved Outcome during Sepsis
Authors: Kumpf Oliver , Gürtler Kathleen , Sur Saubashya , Parvin Monalisa , Zerbe Lena-Karoline , Eckert Jana K , Weber Alexander N R , Oh Djin-Ye , Lundvall Linn , Hamann Lutz , Schumann Ralf R
Published: December 2021

LPS binding protein (LBP) is an important innate sensor of microbial cell wall structures. Frequent functionally relevant mutations exist and have been linked to influence susceptibility to and course of bacterial infections. We examined functional properties of a single nucleotide polymorphism resulting in an exchange of phenylalanine to leucine at position 436 of LBP (rs2232618) and compared the frequent variant of the molecule with the rare one in ligand binding experiments. We then stimulated RAW cells with bacterial ligands in the presence of serum obtained from individuals with different LBP genotypes. We, furthermore, determined the potential effects of structural changes in the molecule by in silico modeling. Finally, we analyzed 363 surgical patients for this genetic variant and examined incidence and course of sepsis following surgery. We found that binding of LBP to bacterial ligands was reduced, and stimulation of RAW cells resulted in an increased release of TNF when adding serum from individuals carrying the F436L variant as compared with normal LBP. In silico analysis revealed structural changes of LBP, potentially explaining some of the effects observed for the LBP variant. Finally, patients carrying the F436L variant were found to be similarly susceptible for sepsis. However, we observed a more favorable course of severe infections in this cohort. Our findings reveal new insights into LPS recognition and the subsequent activation of the innate immune system brought about by LBP. The identification of a genetic variant of LBP influencing the course of sepsis may help to stratify individuals at risk and thus reduce clinical complications of patients.
Agnoea subgilvida (Walsingham, 1901), specie nuova per la fauna italiana e checklist e distribuzione delle specie del genere Agnoea Walsingham, 1907 (= Pseudatemelia Rebel, 1910) presenti in Italia (Lepidoptera, Lypusidae)
Authors: Timossi Giovanni
Published: December 2021

Viene segnalata per la prima volta per l’Italia Agnoea subgilvida (Walsingham, 1901) scoperta all’Isola d’Elba. La specie in oggetto era considerata un endemita della Corsica e il suo rinvenimento nell’arcipelago toscano ne estende la distribuzione nota.
Endobronchial hamartoma in a young COVID-19 symptomatic woman. Radical endoscopic treatment with a disposable bronchoscope. Case Report
Authors: Guarino Carmine , Cesaro Cristiano , La Cerra Giuseppe , Lucci Raffaella , Cesaro Flavio , Zamparelli Enzo , Gaglione Gianfranco , Pontarelli Agostina , De Rosa Annunziata , Parrella Roberto
Published: December 2021

Pulmonary hamartomas represent the most frequent family of benign lung tumors that typically involve the lung parenchyma and only rarely grow as endobronchial tumors. The elective treatment of endobronchial hamartoma is the bronchoscopic resection, and in those cases in which tumor extension and localization makes it not possible, surgical treatment must be evaluated. Patients with symptomatic COVID-19, hospitalized, frequently undergo a chest CT scan and in some cases, occasional findings may emerge, requiring diagnostic investigations such as bronchoscopy and interventional pulmonology procedures. Therefore, in such a delicate pathological condition, such as COVID-19, the need to perform bronchoscopy and interventional pulmonology procedures, minimizing the risk of viral transmission and ensuring necessary assistance, represents a great challenge for pulmonologists. In this article authors describe, for the first time in literature, a rare case of endobronchial hamartoma, radically resected using a single use bronchoscope, in a young female patient hospitalized for symptomatic COVID-19.
Management Outcomes of Mesenteric Cysts in Paediatric Age Group
Authors: Tripathy Prasanta Kumar , Jena Pradeep Kumar , Pattnaik Kaumudee
Published: December 2021

Background:

Mesenteric cysts are rare intra-abdominal masses and high index of suspicion is required to clinically suspect this pathology and make a definitive diagnosis. They are most commonly located in the ileal mesentery but can be located anywhere along the gastrointestinal tract mesentery and may extend into the retroperitoneum. The rarity of these anomalies and diversity of clinical picture pose challenges in the diagnosis and operative management. The objective of this study is to determine the demographic pattern, clinicopathological diagnosis and management outcome of mesenteric cysts in our hospital.

Materials and Methods:

This retrospective study was conducted on children operated for mesenteric cysts from October 2013 to September 2020. Statistical analysis was performed using Open Epi Version 3.01.

Results:

Out of 32 children with a diagnosis of mesenteric cyst, 78% were below 5 years of age. Small intestine was affected in 26 cases and large bowel mesentery was the site of origin in six cases. Complete excision of mesenteric cyst was possible in all cases. Bowel resection was required in ten cases (31%) to enable complete excision. Bowel resection was required more often in children operated on emergency than those with elective surgery, and is statistically significant (P = 0.04; confidence interval: 0.05–0.96, odds ratio: 0.23). An uncommon co-existence with ileal atresia and detection of rare chylolymphatic cyst in another infant were also remarkable findings. Histopathology proved the diagnosis in all cases. There was no mortality or recurrence during hospitalisation and follow-up, which ranged from 3 months to 3 years.

Conclusions:

Mesenteric cysts present with diverse clinical features and children below 5 years of age are most commonly affected. Complete surgical excision is the optimal treatment and may require bowel resection in significant number of cases, especially those operated during emergency. Histopathology is the gold standard for diagnosis.
Is there any Benefit with Pantoprazole Treatment in Infantile Hypertrophic Pyloric Stenosis?
Authors: Fourie Natasha , Arnold Marion , Banieghbal Behrouz , Marchant Samantha Lynn
Published: December 2021

Context:

Previous studies demonstrated faster correction of metabolic derangement associated with hypertrophic pyloric stenosis with pre-operative intravenous (IV) histamine-2 receptor antagonists.

Aims:

We investigated if similar outcomes are achieved with IV pantoprazole, a proton-pump inhibitor (PPI), including the subgroup of delayed presenters in the South African setting.

Settings and Design:

A 5-year retrospective record review (January 2014–December 2018) compared the rate of metabolic correction in patients with hypertrophic pyloric stenosis at two tertiary centres.

Subjects and Methods:

One centre routinely administers IV pantoprazole (1 mg/kg daily) preoperatively (PPI group) and the other does not (non-PPI group). Fluid administration, chloride supplementation and post-operative emesis were evaluated.

Statistical Analysis:

Spearman's rank correlation coefficient was used to calculate statistical significance for discrete dependent variables. Continuous variables were compared between the groups using the Student t-test. Fisher's exact contingency tables were used to classify categorical data and to assess the significance of outcome between two treatment options. P < 0.05 was considered statistically significant.

Results:

Forty-two patients received IV pantoprazole and 24 did not. The mean time of metabolic correction was 8 h shorter in the PPI group (P = 0.067). Total pre-operative chloride administration correlated to the rate of metabolic correction in both cohorts (P < 0.0001). Profound hypochloraemia (chloride <85 mmol/l) was corrected 23 h faster in the PPI group (P < 0.004). Post-operative emesis was noted: 0.45 episodes/patient in the PPI group and 0.75 episodes/patient in the non-PPI group (P = 0.01).

Conclusions:

Pre-operative IV pantoprazole administration showed a faster correction of metabolic derangements, and in profound hypochloraemia, the correction occurred substantially faster in the PPI group. Post-operative emesis was significantly less frequent in the PPI group.
Appendix around Ileocolic Intussusception with Acute Appendicitis
Authors: Ravikanth Reddy
Published: December 2021

Intussusception and appendicitis share similar clinical features. However, their concurrent occurrence is exceedingly rare. Appendix involvement in intussusception must be ruled out when appendix is not visualized on high-resolution ultrasonography in cases with ileocolic intussusception. This case report describes the sonological appearance of a combination of ileocolic intussusception with concurrent acute appendicitis in a 4-year-old child.
Phytochemical Screening, Antioxidant, Antibacterial, and Antidandruff Activities of Leaf Extract of Artemisia indica
Authors: Dahal Pragyan , Bista Govinda , Dahal Prasanna
Published: December 2021

Background:

Artemisia indica is a traditionally used medicinal plant in the treatment of various conditions such as loss of appetite, abdominal discomfort, antimalarial infection, dermal wound infection, etc.

Objectives:

This study aims to determine the presence of phytochemical content, antioxidant, antibacterial, and antidandruff activity of leaf extract of A. indica.

Materials and Methods:

Dried ground leaves were subjected to a cold extraction method using an absolute concentration of methanol, ethanol, and water. Total phenolic, flavonoid, and proanthocyanidin content was estimated by using a linear regression equation from the calibration curve and expressed in terms of gallic acid equivalent (GAE) and rutin equivalent (RE). Antioxidant properties were determined using DPPH (1,1-diphenyl-2-picryl-hydrazyl), nitric oxide, and hydrogen peroxide assay, and their IC50 values were calculated. The antibacterial activity was tested using the agar well diffusion method against the common five pathogenic strains, and the zone of inhibition is compared with gentamicin (1 mg/mL) as a positive control. The minimum inhibitory concentration (MIC) value was obtained by the microbroth dilution method. The antidandruff assay was performed on Malassezia furfur by the disk diffusion method into Sabouraud dextrose agar overlaid with 1 mL of olive oil, and the MIC value was determined by the microtiter plate method.

Results:

The result showed that the Artemisia methanolic extract represents ample content of phenolics (248±3.29 mg/g of GAE), flavonoids (222.33±4.41 mg/g of RE), and proanthocyanidin (222.83±1.62 mg/g of RE equivalent). The antioxidant assay revealed that methanolic extract has the highest radical scavenging activity followed by aqueous extract and then ethanolic extract. The antibacterial activity of leaf extract shows MIC value ranging from 6 to 25 μg/mL against various human pathogenic bacteria. The antidandruff assay showed that MIC value of methanolic extract is lesser than that of ethanolic extract (350<400) mg/mL.

Conclusion:

The results concluded that leaf extract of A. indica contains phenolics, flavonoids, and proanthocyanidin and exhibits adequate antibacterial, antidandruff, and antioxidant activity.
Quantitative Structure–activity Relationship Modeling of Some Naphthoquinone Derivatives as Inhibitors of Pathogenic Agent IDO1
Authors: Farsani Sajjad Jazayeri , Asadpour Saeid , Semnani Abolfazl , Nasab Shima Ghanavati
Published: December 2021

Quantitative structure–activity relationship (QSAR) was performed to analyze naphthoquinone derivatives as an inhibitor of indoleamine 2,3-dioxygenase pathogen via multivariate regression (MLR) and artificial neural network. The best descriptors were picked to construct the QSAR. Two sets of exercises and experiments were also performed using Principal Component Analysis for multiple linear regression (MLR). A quantitative model was then proposed based on these analyses and the activity of the compounds based on multivariate statistical analysis was interpreted. The study finally revealed that although the MLR model can predict the activity of the compounds to some extent, the artificial neural network (ANN) model results indicate that the predictions obtained by the neural network are much better and more efficient than other models. The neural network was also used where three coefficients of correlation were used. The results uncovered that the ANN model is statistically significant and has good stability for data validation for the validation method. Share Descriptive relationships of structure and activity were also examined.
Temporomandibular joint dysfunction in some rheumatological diseases (case–control study)
Authors: Ahmed Amany S. , Zaghloul Mohammad I. , Abutaleb Faten A.S. , El-Deeb Ali E.
Published: December 2021

Background

The incidence of temporomandibular joint (TMJ) involvement in inflammatory arthritis, such as rheumatoid arthritis, is often underestimated. Noninvasive imaging modalities such as musculoskeletal ultrasound (MSUS) are used to evaluate the TMJ.

Aim

This study was conducted to determine the affection of TMJ in some rheumatological diseases using MSUS.

Patients and methods

The study included 50 participants divided into two groups: group I included 40 patients (80 TMJ joints) with four rheumatological diseases, and group II included 10 apparently healthy persons (20 TMJ joints) matched in age and sex with the patients, chosen as a control group. All patients were diagnosed clinically and through laboratory investigations. Thereafter, they were assessed for pain degree by visual analog scale (VAS); disease activity using disease activity score-28, systemic lupus erythematosus disease activity index, and Western Ontario and McMaster Universities Arthritis Index; functionally using Modified Health Assessment Questionnaire, and Fonseca questionnaire; and underwent imaging assessment using panoramic radiography and musculoskeletal ultrasonography.

Results

Erosions were detected in 12.5% of the examined TMJs by panoramic radiography, whereas they were detected in 32.5% by MSUS. TMJ effusion and disc displacement could not be detected by panoramic radiography, whereas effusion was detected by MSUS in 23.8% of the examined TMJs and disc displacement was detected in 27.5%.

Conclusion

MSUS is more sensitive in detection of TMJ affection than panorama x-ray. Radiographic pathological findings by MSUS and panorama x-rays were more in temporomandibular joint disorders of patients with rheumatoid arthritis followed by systemic lupus erythematosus and then osteoarthritis, and finally, psoriatic arthritis.
Optical coherence tomography angiography of ill-defined choroidal neovascularization with fluorescein angiography
Authors: Yonis Doaa A.E. , Wasfy Tamer E. , Atef Mohamed S.E. , Serag Yasser R.
Published: December 2021

Background

Optical coherence tomography angiography (OCTA) is used to diagnose choroidal neovascularization (CNV). It can detect blood flow at different levels using an en face platform and directly provides morphological identification of pathological microvascular lesions. CNV results in the growth of blood vessels from the choroid mediated by Bruch's in the subretinal pigment epithelium or subretinal area.

Aims

This study was done to study the morphological structure of ill-defined CNV with fundus fluorescein angiography (FFA) by OCTA.

Patients and methods

This prospective cross-sectional, nonrandomized, noninterventional study that was done on 48 eyes of 35 patients who were diagnosed to have CNV by FFA, OCT, and OCTA imaging was performed using Topcon Corp. On OCTA imaging, the fovea was used. After full history and complete ophthalmologic examination, FA, OCT, and OCTA was done for all patients after papillary dilatation with Mydrapid eye drops.

Results

OCTA was superior to FFA in detection of clear vascular network, the exact location, and classification of CNV. It showed a statistically significant difference (P=0.001). Occult CNV and CNV suspicious in FFA appeared mainly as type I that had more volumetric angiographic information of CNV in choriocapillaris.

Conclusion

OCTA is better at detecting the exact type and location of ill-defined CNV (occult type-I CNV) compared with FFA and for defining the vascular network with high accuracy. It was able to aid in making the diagnosis in cases where evidence of CNV is uncertain following FFA.
Oocyte activation
Authors: Gopinath P. M. , Vaithianathan Hema
Published: December 2021

Though the application of advanced assisted reproductive technologies, such as in vitro fertilization and intracytoplasmic sperm injection (ICSI), circumvents many factors resulting in infertility, it still has its challenges. Among the various reasons, total fertilization failure attributed to oocyte activation deficiency (OAD) is a recognized cause. The application of assisted oocyte activation (AOA) during ICSI has been reported to overcome this issue and improve outcomes. The objective of this review article is to provide an overview of the currently available data regarding oocyte activation, identify areas for further research, and draw conclusions. Many diagnostic methods are developed to diagnose OAD, and thus, it helps to streamline its application. Similarly, many methods of activation are studied, but there is no proposed standardization in techniques, which indicates this area of expertise needs more research for broad application. Hence, AOA cannot be universally applied, as it is not beneficial in all cases of suspected OAD, which eventually points to the need that consensus guidance in clinical practice for the use of AOA should be available to guide clinicians. Importantly, a couple should be well informed about the advantages and risks associated with AOA-ICSI before application.
Fertility in a woman with bilateral ovarian cancer
Authors: Patwardhan Sadhana , Ketkar Mangala , Agrawal Nitya
Published: December 2021

Ovarian cancer is one of the most lethal gynecological malignancies. It is estimated that 10% of ovarian cancer cases will be diagnosed in women of reproductive age and >80% would be in advanced stage. Conservative treatment can be carried out for Stage IA, B, C1, C2, C3 (International Federation of Gynecology and Obstetrics) to preserve fertility. Evidence-based data from the descriptive series suggest that in selected cases, the preservation of the uterus and at least one part of the ovary does not lead to a high risk of relapse. Here, we present the case report of a patient who underwent bilateral salpingo-oophorectomy for early stage ovarian cancer and borderline tumor, conceived through in vitro fertilization, with successful pregnancy outcome.
Spatiotemporal analyses of the epidemiological characteristics of diabetes mellitus
Authors: Rhee Sang Youl
Published: December 2021

Research based on spatiotemporal analysis has been conducted to identify various factors that can affect an individual’s or community’s degree of health and disease. These spatiotemporal studies can effectively illustrate patterns in disease frequency, features, and temporal flow in different parts of a country. Furthermore, identifying these regional characteristics can aid in the development of disease prevention or intervention strategies.
Die Rolle des mitteleuropäischen Raumes in der Entwicklung der slowenischen Kirchenmusik des 19. Jahrhunderts
Authors: Nagode Aleš
Published: December 2021

Die Rolle des mitteleuropäischen Raumes in der Entwicklung der slowenischen Kirchenmusik des 19. Jahrhunderts