bluuebunny/crossref_metadata_2025 huggingface dataset:
Sustainable urban planning to control flood exposure in the coastal zones of China
Authors: wu yijing , Li Jingwei , Wu Haoyuan , Duan Yongqiang , Shen Hanru , Du Shiqiang
Published: April 2024

Context.
Sustainable development in coastal zones faces escalating flood risk in the context of climate change and urbanization, and the rapid urban growth in flood zones has been one of the key drivers. Therefore, understanding the urban exposure to flooding (UEF) and its future scenarios is important in coastal zones.
Objectives.
The objectives of this study were: (1) to assess the future dynamics of UEFs in China's coastal zones, and (2) to identify a sustainable way of urban planning in controlling the growth of UEFs.
Methods.
Future UEFs in coastal China were assessed during 2020–2050 by combining urban expansion model, scenario analysis, and flood exposure assessment. Alternative scenarios were considered of shared socioeconomic pathways (SSPs), representative concentration pathways (RCPs), strategies of urban planning.
Results.
The results show that the 1000-year flood UEFs along coastal China was expected to grow under SSP2-RCP4.5 from 9,879 km2 in 2020 to 13424 (12997–13981) km2 in 2050, representing an increment of 35.88% (31.56–41.52%). Alternatively, the strategy of sustainable development planning could reduce the newly added UEF by 16.98% (15.63–18.67%) in a 1000-year flood scenario.
Conclusions.
The findings proved that the ways of urban growth matters in terms of affecting food exposure and risk and flood risk should be incorporated into urban planning for a sustainable landscape. The study could offer methodology and support for sustainable development strategies in reducing future urban flood risk.
The most severe case of multiple osteochondromas in paleopathological record is from an Early Medieval burial site in the Venetian Lagoon
Authors: Viva Serena , Lonoce Norma , Bigo Lorenzo , Cadamuro Silvia , Gelichi Sauro
Published: April 2024

In recent years, paleopathological cases from ancient contexts are being increasingly taken into account to reconstruct the clinical history of a number of diseases, in particular congenital ones, at times still featuring in the genes of present-day populations. The skeleton of a male (T97) with an estimated age-at-death of 40–45 years has been found in the Early Medieval phase of an archaeological site in the Venetian Lagoon (north-east Italy). Through the osteoarchaeological study, full skeletal CT, histopathological examination, and comparison with other case studies a diagnosis was made. It is now possible to provide a detailed evaluation of the most severe case of multiple osteochondromas (MO) ever to be documented by paleopathology. T97 currently appears to be the most severe case of MO ever to be attested from archaeological context. No skeletal remains documented so far, either in Italy or abroad, have revealed such a high number of osteochondromas and chondrosarcomas, i.e. malignant mutations. Moreover, the individual in question appears to have developed all the characteristic features of the pathology, resulting in a unicum in the international landscape. The present case of multiple osteochondroma is useful in understanding the natural clinical dynamics of this disease, providing for the first time a CT scan of a complete skeleton affected, as well as the survival of an individual with severe disabilities in a Medieval context.
Acupuncture for neuropathic pain in patients with dry eye disease: protocol for a systematic review and meta-analysis
Authors: Zhu Yan , Wang Shumin , Wei Juan , Zu Guangquan , Gao Qian , Wu Yunchuan , Wei Qingbo
Published: April 2024

Introduction Various randomized trials have demonstrated the therapeutic effect of acupuncture on the neuropathic pain (NP) in patients with dry eye disease (DED). However, the effectiveness and safety of acupuncture remain unclear. The objective of this systematic review is to assess the effectiveness and safety of acupuncture treatment related to NP in DED patients. Methods and analysis We will conduct searches across a range of databases including four English databases (PubMed, Cochrane Library, Embase, and Ovid), three Chinese databases (China National Knowledge Infrastructure, Wanfang, Chongqing VIP Information), three Japanese databases (Japan Agency for Science and Technology and Japan Medical Abstracts Service), as well as three Korean databases (Korean Medical Database, Oriental Medical Advanced Retrieval System, together with Research Information Service System) for papers published between January 2014 and October 2023. The search will not be restricted by language or publication date and focused solely on randomized controlled trials. Two researchers will independently perform data extraction, management, and analysis. Primary outcomes will consist of Schirmer's I test (SIT), tear breakup time (TBUT), ocular surface disease index scores (OSDI), neuropathic Pain Symptom Inventory modified for the Eye (NPSI-Eye), together with ocular pain assessment survey (OPAS). Secondary outcomes will consist of visual analogue scale (VAS) scores for ocular symptoms along with any acupuncture-related adverse events (AEs). Meta-analysis will be performed using Review Manager V.5.4. Meanwhile, the risk of bias will be independently evaluated utilizing the tool of "Risk of Bias" provided by Cochrane.Human Ethics and Consent to Participate declarations: not applicable.PROSPERO registration numberCRD42023487570.
Gender-Based Differences in Common Mental Disorders and Inequities in Access in Bangladesh
Authors: Saif Saiful Islam , Kushal Sayedul Ashraf , A Yahia Md , Azdi Zunayed Al
Published: April 2024

Bangladesh, the eighth-largest country in the world, has 162 million inhabitants. At the moment, 16.8% of individuals have mental health problems, which is roughly 6% more than the prevalence worldwide. However, globally, women are suffering mental health problems nearly twice as much as men but access mental health services less than men. This research aims to find gender-based differences in the prevalence of common mental health problems and inequity in mental health access in Bangladesh. In order to conduct this research, we used a desk review, which included both research and gray articles. Results depict that in patriarchal societies like Bangladesh, gender-based mental health inequity is pervasive, and women may be more susceptible to common mental health disorders, such as depression and anxiety. Contrary to this, this research has provided a broad overview of the gender-based inequity in mental health accessibility. We offered recommendations from our study and other literature and discussed how the results had ramifications.
Effect of Co 2+ substituted La 2 CuO 4 nanoparticles: Structural, morphological, optical and magnetic behaviour
Authors: Dash Chandra Sekhar , Yuvaraj S. , Jothiramalingam R. , Iqbal S. , Isaac R. S. Rimal , Bahajjaj Aboud A.A. , Sundararajan M. , Sukumar M. , Rajadurai L.
Published: April 2024

Impact of Co2+ doping on the properties of the structural, magnetic, functional and optical of La2CuO4 system formed by combustion process. Every sample of lanthanum cuprate was examined. The development of single-phase orthorhombic crystals with a Bmab space group was verified by X-ray diffraction patterns. The monophasic orthorhombic lattice structure of the material has crystallite size that falls between 28 and 41 nm. The lattice constant falls between a = 5.361 Å − 5.349 Å, b = 5.410 Å − 5.399 Å & c = 13.160 Å − 13.148 Å. The XRD of La2CuO4 perovskite nanomaterials correspond well with the calculated ones, with χ2 values closer to 1. Energy gap values decreases from 1.75 to 1.68 eV due to the quantum confinement. The hysteresis curves recorded at 300 K show that coercivity ranges from 210.09 to 177.37 Oe as the content decreases, confirming that the crystallite size increase. The samples were with soft ferromagnetic behavior found in the VSM study.
Ozil Phacoemulsification Handpiece versus Phacofragmatome in the Management of Dropped Lens Fragments: A Randomized Controlled Trial
Authors: Rana Vipin , Sinha DK , Dangi meenu , Bandopadhyay S , Kumar Ashok , Sharma Vijay Kumar , Tripathi Amit Nadan , Sharma Neeraj
Published: April 2024

Purpose
In cataract surgery, dislocation of lens fragments into the vitreous cavity is a rare but significant complication. This study compares the effectiveness of the Ozil phacoemulsification handpiece with the traditional phacofragmatome in managing posteriorly dislocated lens fragments to improve patient outcomes.
Methods
A prospective, randomized study was conducted at a tertiary care hospital in eastern India from January to June 2023, involving 40 patients divided into two groups using block randomisation. Group 1 underwent surgery with the phacofragmatome, while Group 2 used the Ozil handpiece. The primary objective was to evaluate the surgical duration and intraoperative complications, with secondary objectives assessing postoperative Best Corrected Visual Acuity (BCVA), incidence of Cystoid Macular Edema (CME), and safety of surgical sites.
Results
The use of the Ozil handpiece significantly reduced surgical duration (110 ± 2.54 seconds) compared to the phacofragmatome (152 ± 2.23 seconds, p < 0.001) and minimized the risk of lens fragments falling onto the retinal surface. No significant difference was found in postoperative BCVA or the incidence of CME between the two groups, indicating similar visual outcomes and safety profiles.
Conclusion
The Ozil phacoemulsification handpiece offers a more efficient and potentially safer alternative for managing posteriorly dislocated lens fragments in cataract surgery compared to the traditional phacofragmatome. These findings suggest the Ozil handpiece could improve surgical outcomes and patient safety.
Analysis of Ensembled Learning using Classical and Quantum Boosting Approaches for Diabetes Mellitus Prediction
Authors: Jha Sujeet Kumar , Adhikari Nanda Bikram
Published: April 2024

The paper focused on the implementation of Quantum machine learning and artificial intelligence techniques in diagnosing
diseases, specifically focusing on diabetes. The paper proposed
an ensemble approach that combined classical algorithms with
quantum processing unit (QPU)--based algorithms to improve
the performance of a model. The diabetes dataset used in the
study is obtained from the (Centre for Disease Control and Prevention (CDC) repository, and the goal is to
classify patients as either diabetic or non-diabetic. The ensemble
algorithms examined in the study include Voting classifier, Adaboost, Xgboost, Catboost, and QPU-based Qboost. While Qboost
demonstrates some quantum speedup, its performance is not
satisfactory. Therefore, the proposed hybrid model is developed
to enhance the performance metrics. The hybrid model achieves
an average accuracy, precision, recall, f1 score, and AUC score
of 0.89, 0.85, 0.95, 0.90, and 0.96, respectively, on the diabetes
dataset. In comparison, the top-performing Adaboost algorithm
achieves an average accuracy, precision, recall, f1 score, and AUC
score of 0.94, 0.91, 0.98, 0.94, and 0.98, respectively. The paper
concludes that while quantum computing (QC) significantly
improves computation speed, it comes at a slight cost of a 5
\% decrease in classification metrics and 0.186 in the AUC score.
Additionally, the study suggests that further development of Quantum computing
hardware will enhance overall performance metrics.
Validation of the ultra-brief self-report Patient Health Questionnaire-4 (PHQ-4) to measure anxiety and depression in Arabic-speaking adults
Authors: Obeid Sahar , Hemade Ali , Malaeb Diana , Sakr Fouad , Dabbous Mariam , Xu Jiale , Ying Yiwei , Jiang Chen , Meng Runtang , Fekih-Romdhane Feten , Hallit Souheil
Published: April 2024

Background: Anxiety and depression are psychiatric disorders that often coexist and share some features. Developing a simple and cost-effective tool to assess anxiety and depression in the Arabic-speaking population, predominantly residing in low- and middle-income nations where research can be arduous, would be immensely beneficial. The study aimed to translate the four-item composite Patient Health Questionnaire – 4 (PHQ-4) into Arabic and evaluate its psychometric properties, including internal reliability, sex invariance, composite reliability, and correlation with measures of psychological distress.
Methods: 587 Arabic-speaking adults were recruited between February and March 2023. An anonymous self-administered Google Forms link was distributed via social media networks. We utilized the FACTOR software to explore the factor structure of the Arabic PHQ-4.
Results: Confirmatory factor analysis (CFA) indicated that fit of the two-factor model of the PHQ-4 scores was modest (χ2/df= .13/1 = .13, RMSEA = .001, SRMR = .002, CFI = 1.005, TLI = 1.000). Internal reliability was excellent (McDonald’s omega = .86; Cronbach’s alpha = .86). Indices suggested that configural, metric, and scalar invariance were supported across sex. No significant difference was found between males and females in terms of the PHQ-4 total scores, PHQ-4 anxiety scores, and PHQ-4 depression scores. The total score of the PHQ-4 and its depression and anxiety scores were significantly and moderately-to-strongly associated with lower wellbeing and higher Depression Anxiety and Stress Scale (DASS) total and subscales scores.
Conclusion: The PHQ-4 proves to be a reliable, valid, and cost-effective tool for assessing symptoms related to depression and anxiety. To evaluate the practical effectiveness of the Arabic PHQ-4 and to further enhance the data on its construct validity, future studies should assess the measure in diverse contexts and among specific populations.
Solvability of a System of Nonlinear Integral Equations with a General Kernel
Authors: Dehghan Akram , Roshan Jamal Rezaei
Published: April 2024

This study establishes the adequate conditions for the solvability of a Volterra-type nonlinear system of integral equations with some general kernels. The proof of the existence result is established in the space C (I; B 1 B 2), where B 1 and B 2 represent two arbitrary Banach spaces. Darbo’s fixed point theorem and the methodologies for noncompactness measures are employed in our analysis. Moreover, we study the Cauchy problem for a system of fractional di¤erential equations. Finally, we present some examples in sequence spaces that demonstrate the application of our results to specific kernels and a class of more general kernels that satisfy a specific condition.
Mathematics Subject Classification: 47H08, 47G15, 47H10.
Research History, Current Trends, and Future Prospects of Liquid Biopsy in Triple-Negative Breast Cancer: An Analysis from a Global Perspective
Authors: Qu Yi , Wan Jixian , Li Ruihan , Li Xinyuan , Li Han , Li Yang , Huang Shengnan , Zhang Tingting , Yang Dawei , Chen Dongliang
Published: April 2024

Liquid biopsy has emerged as a significant technique in the field of triple-negative breast cancer, garnering widespread attention since 2012. Despite this, there remains a notable absence of bibliometric assessment in this area. This study screened 506 pieces of literature obtained from Web of Science (WoS) searches and selected 347 papers published between 2012 and 2024. Various software tools, including VOSviewer, CiteSpace, Bibliomatrix, and Scimago Graphica were used to visualize the results of the analyses. Through careful examination of visual graphs, this study conducted in-depth profiling mining, suggesting great potential and promise in this area. The linkage map of countries highlights the central roles played by the USA and China in this field over the past twelve years. Furthermore, the analysis of literature co-citations reveals a predominant focus on subtypes, cell models, and targeted therapies. Keyword analysis indicates previous emphasis on sensitive targets and advancements in the nano-field. Moreover, the evolution of keywords over time illustrates a transition from mechanistic inquiries to investigations spanning diagnosis, immunotherapy, and prognosis. These results offer valuable insights into the research process and potential future directions. Additionally, this paper integrates keywords, co-cited cores, coupling centrality, and visual analysis results of the most cited literature, using techniques such as timeline graph clustering and emergent words. Major hotspots are summarised, such as "biomarker", "target", "biological model", and "Immunotherapy inhibitors".
Neural Network-Driven Counter-Pulsation in Pulsatile Extracorporeal Membrane Oxygenator(ECMO): Enhancing Real-time Pulse Discrimination and Control Efficiency
Authors: Jang Hyun-Woo , Yoo Chang-Young , Kang Seong-Min , Choi Seong-Wook
Published: April 2024

Implementing counter-pulsation (CP) control in pulsatile extracorporeal membrane oxygenator (p-ECMO) systems offers a refined approach to mitigate risks commonly associated with conventional ECMOs. To attain CP between the p-ECMO and heart, accurate detection of heartbeats within blood pressure (BP) waveform data becomes imperative, especially in situations where measuring electrocardiograms (ECGs) are difficult or impractical. In this study, a cumulative algorithm incorporating filter-type neural networks was developed to distinguish heartbeats from other pulse signals generated by the p-ECMO, reflections, or motion artifacts in the BP data. A control system was implemented using the cumulative algorithm that detects the heart rate (HR) and maintains a proper interval between the p-ECMO's pulses and heart beats, thereby achieving CP. To ensure precise circulatory support control, the p-ECMO setup was connected to a mock circulation system, with the human BP waveforms being replicated using a heart model. The algorithm could maintain CP perfectly when the HR remained constant; however, owing to a 0.48-s delay from the HR detection to CP control, the success rate of the CP control decreases when a sudden increase in the HR occurred. In fact, when the HR varied by ± 5 bpm every minute, the CP success rate dropped to 78.62%, however this was still higher compared to the 25.75% success rate achieved when no control was applied.
Histopathological correlation of brain tumor recurrence vs radiation effect post-radiosurgery as detected by MRI Contrast Clearance Analysis: A validation study
Authors: Goulenko Victor , Madhugiri Venkatesh Shankar , Bregdy Amade , Recker Matthew , Lipinski Lindsay , Fabiano Andrew , Fenstermaker Robert , Plunkett Robert , Abad Ajay , Belal Ahmed , Alberico Ronald , Qiu Jingxin , Prasad Dheerendra
Published: April 2024

Purpose: The differentiation between adverse radiation effects (ARE) and tumor recurrence or progression (TRP) is a major decision-making point in the follow-up of patients with brain tumors. The advent of immunotherapy, targeted therapy and radiosurgery has made this distinction difficult to achieve in several clinical situations. Contrast clearance analysis (CCA) is a useful technique that can inform clinical decisions but has so far only been histologically validated in the context of high-grade gliomas.Methods This is a series of 7 patients, treated between 2018 and 2023, for various brain pathologies including brain metastasis, atypical meningioma, and high-grade glioma. MRI with contrast clearance analysis was used to inform clinical decisions and patients underwent surgical resection as indicated. The histopathology findings were compared with the CCA findings in all cases.Results All seven patients had been treated with gamma knife radiosurgery and were followed up with periodic MR imaging. All patients underwent CCA when the necessity to distinguish tumor recurrence from radiation necrosis arose, and subsequently underwent surgery as indicated. Concordance of CCA findings with histological findings was found in all cases (100%).Conclusions Based on prior studies on GBM and the surgical findings in our series, delayed contrast extravasation MRI findings correlate well with histopathology across a wide spectrum of brain tumor pathologies. CCA can provide a quick diagnosis and have a direct impact on patients’ treatment and outcomes.
Experimental investigation on bi-component wall film evaporation on a hot wall
Authors: Yan Yan'an , He Yushuo , Fei Chunguang , Zhang Qifan
Published: April 2024

Spray-wall impingement is a widely observed phenomenon in modern internal combustion engines. The formation and evaporation of the wall film significantly impacts the fuel-air formation as well as combustion and exhaust pollutants. In this study, fuel film evaporation experiments were carried out under a constant wall temperature condition for n-decane, n-dodecane, and their blends in order to gain a better knowledge of film evaporation characteristics. Moreover, the effects of wall temperature and mass ratio of mixed fuels on wall film thickness, area, volume, and lifespan were investigated. Furthermore, it was found an unexpected phenomenon in which the lifetime of the bi-component fuel film might be shorter than that of the pure n-decane fuel film under certain operating conditions. Finally, the processed data provided solid data to validate the unsteady one-dimensional analytical models.
Optimal Control Strategies for Sustainable Energy Management in Electric Power Grids: A Hybrid Model Predictive Approach
Authors: Roudaki SeyedHamed MirMohammadAli , Yazdani Kaveh
Published: April 2024

Energy infrastructure development in rural and remote areas of the planet is key to sustaining human development. This study establishes an optimal control strategy that can efficiently manage an electric grid comprised of various renewable and non-renewable energy sources for a medium sized community. Simple power dynamics are modeled and used for representing the components present on the grid. A hybrid model predictive control scheme is implemented for choosing an optimal mode and set of inputs for the system for tracking both a constant and load-varying power demand profile.
Major depressive disorder, neuroticism, suicidal behaviors, and depression severity are all associated with neurotoxic immune networks and their intricate interactions with metabolic syndrome.
Authors: Maes Michael , Jirakran Ketsupar , Vasupanrajit Asara , Zhou Bo , Tunvirachaisakul Chavit , Almulla Abbas F.
Published: April 2024

Background
Major depressive disorder (MDD) is considered to be a neuroimmune disorder. However, there are no data regarding the association between comprehensive immune profiles and their interactions with the metabolic syndrome (MetS) in predicting neuroticism, suicidal behaviors, and severity of outpatient MDD (OMDD).
Methods
We assayed 48 serum cytokines, chemokines, and growth factors using a multiplex assay in 67 healthy controls and 66 OMDD patients. Around 50% of the OMDD and control participants had a diagnosis of MetS.
Results
Ten differentially expressed proteins (DEPs) were upregulated in OMDD (i.e., CXCL12, TNFB, PDGF, CCL11, IL9, IL4, CCL5, CCL2, CCL4, IL1RN), indicating an immune, defense and stress response. Six DEPs were downregulated (VEGFA, IL12, CCL3, CSF1, IL1B, NGF), indicating lowered neurogenesis and regulation of neuron death. Significant interactions between OMDD and MetS caused a) substantial increases in TNF signaling, and upregulation of IL4, IL17, TNF, TNFB, CCL2, CCL5, PDGF, IL1RN; and b) downregulation of VEGFA and FGF. A large part of the variance in neuroticism (26.6%), suicidal behaviors (23.6%), and the MDD phenome (31.4%) was predicted by immunological data and interactions between MetS and CCL5, TNFB or VEGFA.
Discussion
OMDD is characterized by an immunoneurotoxic profile which partly explains neuroticism, suicidal behaviors, and the phenome’s severity. Lowered IL-10 and increased neurotoxicity are characteristics of OMDD and other depression phenotypes, including severe first-episode inpatient MDD. The presence of MetS in OMDD considerably exacerbates immunoneurotoxicity. Consequently, immune studies in MDD should always be performed in subjects with and without MetS.
The Utility of Anatomy Assessment in Preclinical Undergraduate Medical Curriculum: A Scoping Review Protocol
Authors:   Department of Basic Sciences, Faculty of Dentistry, Universiti Sains Islam Malaysia, Kuala Lumpur, MALAYSIA, Alias Aspalilah ,   Department of Forensic Odontology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, INDONESIA, Abas Razif ,   Department of Human Anatomy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor, MALAYSIA, Choy Ker Woon ,   Institute of Pathology, Laboratory and Forensic Medicine (I-PPerForM), Universiti Teknologi MARA, Selangor, MALAYSIA,   Department of Anatomy, Faculty of Medicine, Universiti Teknologi MARA, Selangor, MALAYSIA, Wong Kah Hui ,   Department of Anatomy, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, MALAYSIA, Hadie Siti Nurma Hanim ,   Department of Anatomy, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, MALAYSIA
Published: April 2024

Anatomy has been taught predominantly in the preclinical years. However, little guidance exists for medical educators in designing appropriate assessments of anatomy knowledge. In general, medical schools implement and determine their own curricula and methods of assessment. The purpose of this scoping review is to examine the breadth of literature regarding the utility of anatomy assessments, which will be reported whether they have been investigated in terms of validity, reliability, practicality, feasibility, cost-effectiveness, and educational impact in the included resources. This scoping review will be conducted using the Joanna Briggs Institute (JBI) scoping review guideline, and its protocol is outlined to systematically map the utility of anatomy assessments in preclinical undergraduate medical curricula over the past 20 years. Primary data will be searched from relevant studies, review articles, and grey literature sources between 2002 and 2023. The resource searching will be performed using the three-step search strategy, namely review search, study selection, and evidence charting, which will involve four electronic databases and two independent reviewers. As secondary research, this review does not require ethical approval. The review will not only permit better comparisons of anatomy assessment and foster meaningful evaluation of both medical students and teaching establishments to take place in the anticipation of ensuring the constructive alignment in anatomy education but also produce important information on the quality of anatomy assessment in the context of the undergraduate medical curriculum. The findings will be disseminated through journals and conferences targeting anatomy educators worldwide.
ELECTORAL POLITICS AND CHAKMA VOTERS OF ARUNACHAL PRADESH: AN ANALYSIS OF IMPLICATIONS OF CHAKMA VOTERS IN THE FOUR ASSEMBLY CONSTITUENCIES
Authors:   Department of Political Science, Rajiv Gandhi University, Rono Hills. Doimukh-791112, Arunachal Pradesh., Aboh Panjang
Published: April 2024

Chakmas are one of the three refugee groups settled in Arunachal Pradesh that migrated from then East Pakistan between 1964 and 1969 due to alleged religious persecution by their native establishment and the environmental disaster. Since then it has been more than five decades of their stay in Arunachal Pradesh. It is perceived by various civil societies, student organizations, and the general public of the State that these Chakma have a huge number of voters in some assembly constituencies of the State and play a determinant role in deciding the electoral outcome to a great extent thereby reducing Indigenous voters to a minority. This paper attempted to know the strength of Chakma voters across the concerned assembly constituencies of the State from their first enrollment in the electoral roll in 2003 till 2023 and the significance of their votes in determining the electoral outcomes in these constituencies by thoroughly studying, examining and analyzing the data obtained from the office of the chief electoral officer, Nirvachan Bhawan, Itanagar. The study found that at least in one out of four constituencies, the Chakma voters constitute the second largest vote bank and play an important role in determining the electoral outcomes in that particular constituency.
ADMET ANALYSIS OF TRIAZOLE DERIVATIVE: A THEORETICAL INVESTIGATION TOWARDS ITS EVALUATION AS A DRUG CANDIDATE
Authors:   Department of Computer Science and Engineering, Amruta Institute of Engineering and Management Sciences, Bidadi, Karnataka, India - 572109., S. Shreyas ,   Department of Basic Science, Amruta Institute of Engineering and Management Sciences, Bidadi, Karnataka, India - 572109., S.C. Siddaramanna ,   Department of Basic Science, Amruta Institute of Engineering and Management Sciences, Bidadi, Karnataka, India - 572109., R.K. Keerthana ,   Department of Basic Science, Amruta Institute of Engineering and Management Sciences, Bidadi, Karnataka, India - 572109., B.M. Roopini ,   Department of Basic Science, Amruta Institute of Engineering and Management Sciences, Bidadi, Karnataka, India - 572109., B.R. Rakesh ,   Department of Basic Science, Amruta Institute of Engineering and Management Sciences, Bidadi, Karnataka, India - 572109., Patil Smitha ,   Department of Basic Science, Amruta Institute of Engineering and Management Sciences, Bidadi, Karnataka, India - 572109.
Published: April 2024

The present work explores the potency of the 3-Ethoxy-5-phenyl-1H-1,2,4-triazole compound using in-silico experimental techniques. The compound was subjected to ADMET analysis to understand how well the compound can be used as drug. Further the ADMET analysis revealed that the compound showed excellent pharmacokinetic properties with all the values were found to be well within the limits. Further various properties of the compound were evaluated and the boiled egg model analysis revealed that the compound good gastrointestinal absorption property. The toxicity value of the compound were also evaluated.
EFFECT ON COMPRESSIVE STRENGTH OF CONCRETE WITH ADDITION OF SOLID WASTE ASH
Authors:   Students, Department ofCivil Engineering,SethuInstitute ofTechnology, Pullor,Kariapatti., Kabilan S. , Mohammad Multhazim O.A. ,   Students, Department ofCivil Engineering,SethuInstitute ofTechnology, Pullor,Kariapatti., Om Prasath R. ,   Students, Department ofCivil Engineering,SethuInstitute ofTechnology, Pullor,Kariapatti., Arjun R. ,   Students, Department ofCivil Engineering,SethuInstitute ofTechnology, Pullor,Kariapatti., Palani Kumar B. ,   AssistantProfessor, DepartmentofCivilEngineering,SethuInstituteofTechnology, Pullor, Kariapatti.
Published: April 2024

The availability of raw material is very limited due to the increased use of concrete. The standard practice of concreting is dosing, mixing (all raw materials), transportation, on-site compaction, finishing and hardening of all raw materials are done industrially. In developed countries like India, the amount of concrete is more and the availability of raw materials is very limited. A complete replacement of concrete is not possible, because no material can fulfil the role of concrete in terms of strength, durability and workability. To achieve the desired workability, strength and durability of concrete, the entire material must be partially replaced. This article provides an explanation of solid waste ash materials used in concrete. The test procedure involved preparing concrete samples with a percentage of cement replaced by fly ash (0%, 5%, 10% and 15%) and evaluating their compressive strength (7 and 28 days) and split tensile strength after 28 days of curing.
EXPERIMENTALSTUDY ON PARTIAL REPLACEMENT OF COARSE AGGREGATE BY DEMOLISHED CONCRETE WASTE AND ADDED BY PROPHIS JULIFERA ASH
Authors:   Students,Department ofCivil Engineering,SethuInstitute ofTechnology, Pulloor,Kariapatti., Pandi S. , Muthuraja V. ,   Students,Department ofCivil Engineering,SethuInstitute ofTechnology, Pulloor,Kariapatti., Hariprakash K. ,   Students,Department ofCivil Engineering,SethuInstitute ofTechnology, Pulloor,Kariapatti., Jeevarathinam V. ,   Students,Department ofCivil Engineering,SethuInstitute ofTechnology, Pulloor,Kariapatti., Mohamed Meera Maidheen M. ,   AssistantProfessor,DepartmentofCivilEngineering,SethuInstituteofTechnology,Pulloor,Kariapatti.
Published: April 2024

DeteriorationofconcretestructuresmadewithordinaryPortlandcementThe experimental investigations are carried out to study the benefits of Prosopis juliflora in RCC structure by partial replacement of cement. Prosopis juliflora is one among the species that has performed much better than many native woody species. But wide spread Prosopis juliflora has become an invader species, so the removal of the plant is necessary now. At the moment, Prosopis juliflora provides approximately 75% of fuel wood needs of rural people in arid and semiarid regions of India. Prosopis juliflora is xerophytic and is adapted to many soil types under a wide range of moisture conditions. Most of the plant are removed by uprooting and is burnt.
A RARE CASE OF TENOSYNOVIAL GIANT CELL TUMOR IN PALMAR ASPECT OF RING FINGER OF LEFT HAND
Authors:   Post Graduate, Department of Orthopaedics, Chalmeda Anand Rao Institute of Medical Sciences., Mahdi Saniya , Ramu Ch ,   Professor, Department of Orthopaedics, Chalmeda Anand Rao Institute of Medical Sciences.
Published: April 2024

Introduction: Giant cell tumor of the tendon sheath (GCTTS) is an uncommon benign soft tissue tumor of unknown etiology. It is seen more commonly in hand than ankle and foot. It presents as a painless and palpable swelling. Its diagnosis is mostly established by histopathology after surgical resection, although pre-operative imaging and fine-needle aspiration cytology (FNAC) support its suspicion. Herein, a case of GCT of flexor tendon sheath of the right ring finger is reported due to its rarity. Case Report: A 30-year-old female presented with complaints of swelling over the front of the right ring finger for 6months.. The swelling was spontaneous, painless, and very slowly progressive. Examination revealed a 2 cm * 1.5 cm firm swelling situated on the palmar aspect of the right ring finger over proximal inter phalangeal joint. Swelling was well defined, having smooth surface, uniformly firm consistency and could be moved sideways easily. X-ray of the hand showed localized soft tissue shadow in the involved area without any bony involvement. Ultrasonography of the finger showed soft tissue mass.MRI revealed Moderate to intense heterogeneous enhancement suggesting giant cell tumor.. Excisional biopsy was done. Histopathology showed typical features of GCTTS. Conclusion: GCTTS should be kept as a differential diagnosis in soft tissue tumors of hand in adults. FNAC followed by excisional biopsy is diagnostic and curative, but the patient should be followed up for detecting and managing recurrences.
Effect of internal audit, internal control, and audit quality on fraud prevention: Evidence from the public sector in Indonesia
Authors: Zurika Lubis Henny , Sari Maya , Auliya Ramadhany Andi , Chyntia Ovami Debbi , Rahmayati Brutu Istiqomah
Published: April 2024

Fraud prevention entails developing and implementing risk management strategies, particularly regarding fraud, and establishing internal controls and transparent corporate governance practices to eliminate fraudulent activities. This study aims to examine the effect of internal auditors, internal control, and audit quality on preventing fraud at the Inspectorate of North Sumatra Province, Indonesia. The sample included 61 government internal auditors of the Inspectorate of North Sumatra Province, Indonesia. The data collection process was carried out by administering questionnaires using Google Forms. Additionally, this investigation assessed the constructs under scrutiny using a five-point Likert and the partial least square (PLS) approach. The results showed that internal audit has a positive and significant effect on fraud prevention (p < 0.05), internal control has a positive and significant effect on fraud prevention (p < 0.05), and audit quality has no effect on fraud prevention at the Inspectorate of North Sumatra Province, Indonesia (p > 0.05). The Inspectorate of North Sumatra Province, Indonesia, should conduct internal audits, implement an internal control system, and pay attention to the quality of audits to make them more effective as a basis for quality decision-making and fraud minimization.
Aspectos metodológicos e resultados da linha de base do monitoramento da saúde de adultos e idosos infectados por Sars-Cov-2 (Sulcovid-19)
Authors: Saes Mirelle de Oliveira , Rocha Juliana Quadros Santos , Rutz Aline Augusta Medeiros , Da Silva Carine Nascimento , Camilo Lara dos Santos , De Oliveira Brena Costa , Ritta Mauren de Castro , Nunes Lorrany da Silva , Gonçalves Cristiane de Souza , Vieira Yohana Pereira , Garcia Neves Rosália , Duro Suele Manjourany Silva
Published: April 2024

OBJETIVO: descrever a metodologia e a amostra utilizada no estudo além da prevalência dos sintomas da fase aguda da infecção de acordo com variáveis socioeconômicas. MÉTODOS: estudo transversal realizado em Rio Grande com indivíduos infectados pela SARS-Cov-2 no período de dezembro de 2020 a março de 2021. Foram investigados 19 sintomas presentes durante a fase aguda da infecção e analisados, em separado e em categorias de “0-4”, “5-9” e “10 ou mais”, de acordo com sexo, idade e classe econômica. RESULTADOS: 2.919 pessoas fizeram parte da amostra. Os sintomas mais prevalentes foram fadiga (73,7%), dor de cabeça (67,2%), perda de paladar (65,9%), perda de olfato (63,9%) e dores musculares (62,3%). Com relação a ocorrência de sintomas estratificado por sexo, todos os sintomas, exceto tosse produtiva, foram estatisticamente maiores no sexo feminino. Referente à idade, verificou-se que dor de cabeça, dor/desconforto para respirar, perda de paladar, perda de olfato, fadiga, dor de garganta, congestão nasal, diarreia, dores articulares e dores musculares foram estatisticamente maiores entre os adultos (18-59 anos). Quanto à classe econômica, a prevalência dos sintomas falta de ar, dor/desconforto para respirar, alteração de sensibilidade e dores articulares apresentaram aumento linear conforme a redução da classe econômica. CONCLUSÃO: os resultados deste estudo permitiram identificar os sintomas mais frequentes na fase aguda da doença COVID-19 e sua distribuição nos grupos, fornecendo dados para implementação de políticas públicas pelos gestores e respaldo para os profissionais de saúde na assistência a essa população.
O impacto da pandemia COVID-19 na permissividade dos pais: um estudo transversal
Authors: Steinbach Marina , Kammer Pedro Vitali , Da Silva Camila Alvarenga , Santos Kleyslla Souza , De Lima Victor André Silva , Massignan Carla , Bolan Michele da Silva
Published: April 2024

Este estudo transversal buscou descobrir como a pandemia impactou a permissividade dos pais no que se refere ao uso de dispositivos eletrônicos, atividades físicas e interações sociais. Os 466 pais de crianças com idade entre 3 e 10 anos responderam um questionário online sobre a frequência com que permitiram que seus filhos fizessem uso de dispositivos eletrônicos e participassem de atividades sociais após o início da pandemia por COVID-19. As variáveis independentes foram idade e sexo da criança, renda familiar e a quantidade de pessoas que contribuem para a renda, forma de trabalho durante a pandemia, se o respondente era responsável pelas atividades domésticas e se estas afetavam a sua rotina, e quem cuidava da criança quando precisava sair de casa. A avaliação da distribuição das variáveis independentes (categóricas) conforme os 3 graus da variável dependente (mais, menos, igual), e a permissão dos pais (categórica ordinal) foi realizada pelo teste do Qui-quadrado. Após o início da pandemia, os pais permitiram menos brincadeiras/atividades físicas em ambientes públicos (409 – 87,76%) e visita à casa de amigos e familiares (421 – 90,34%); e aumentaram a frequência de permissão do uso de dispositivos eletrônicos para entretenimento (358 -76,8%). A frequência de levar os filhos para mercados, lojas, shoppings e similares não teve alteração significativa (p=0.1494). O presente estudo apontou mudanças significativas na permissividade dos pais devido ao isolamento requerido pela pandemia COVID-19.
Intestinal Enzymes and Lactid Acid Bacteria of Red Tilapia (Oreochromis sp.) Fed Black Soldier Fly (Hermetia illucens) Larvae and Probiotics
Authors: Usmiara Murtia Fauziah Arelia , Nurul Latifah Ma’rufa , Istiqomah Indah , Helmiati Senny , Isnansetyo Alim , Novriadi Romi , Kamarudin Ahmad Syazni
Published: April 2024

This study aimed to determine the effect of probiotics on the intestinal digestive enzyme, morphology and total bacteria of red tilapia (Oreochromis sp.) fed maggot BSF (Hermetia illucens) larvae. The research was conducted using randomized design of two treatments (with probiotics and without probiotics) in three replications. Tilapia (average weight 70 g) were reared for 60 days with diet composition of commercial feed and black soldier fly (Hermetia illucens) larvae at 7:3, respectively. Oral probiotics (Lactococcus sp. JAL 37 and Bacillus sp. PCP 1 (107 cell/g feed) and water probiotic (Klebsiella sp. A2, 105 cell/ml) were administered in seven days interval. We found that administration of maggot BSF (Hermetia illucens) larvae provide no defects on the fish gut morphology. The probiotics application did not change the intestinal cellulose enzyme activity, as well as the intestinal histology parameters, such as villi length, muscular layer thickness and amount of goblet cells. However, the probiotic application significantly enhanced protease and lipase activity (p<0,05), reduced total number of Aeromonas and enhanced total number of lactic acid bacteria (p<0,05).
A HISTORY OF CARBONIC ACID AND THE CENTRAL ROLE OF BICARBONATE IN THE CO2/H2O SYSTEM
Authors: do Lago Claudimir Lucio
Published: April 2024

Carbon dioxide and the related species bicarbonate and carbonate are known for centuries and are deeply involved with modern chemistry knowledge from the beginning. Carbonic acid, by its turn, was intuited more than a century before being synthesized for the first time, which was not obtained, however, without stumbles and mistakes. The equilibrium between HCO3– and CO32– in aqueous medium is free of disputes. However, the interconversion of the other three species is rather controversial. Several papers starting in the beginning of the 19th century until the present days are critically reviewed in order to understand the controversial history of the CO2/H2O system. Finally, experimental evidence and theoretical calculations allow us to place HCO3– as the central species as the conjugate acid for CO32– and conjugate base for two different acids: H2CO3 and CO2.
How Websites of Educational Institutions Create the Virtual Author: News Headlines on University Website
Authors: Ustinova Mariya
Published: April 2024

Internet sites are tools of communication that require a comprehensive study of all aspects, e.g., that of the virtual author who carries out communicative intentions through Internet discourse. A virtual author is a collective figure represented in the discourse of a company website. The authors modelled a virtual author as a collective representative of an educational institution that promotes a positive image of this institution while informing about its agenda and activities. The analysis involved 50 news headlines published on the official website of the Kuzbass Institute of the Federal Penitentiary Service of Russia in 2022-2023. The methods of content and intent analyses made it possible to identify the units of the propositional frame, such as a) participants of events, i.e., subjects; b) predicates that characterize the participants and indicate the type of the event; c) chronotope. The virtual author of the news content appeared to be the Institute as a collective person that expresses their communicative intentions by informing the audience, thus shaping a positive image. As a subject, the virtual author reported news about the object, i.e., the Institution, and implemented the communicative intentions, i.e., to inform and promote a positive image. Each subject was part of the university staff: We are Together; We are a Team; We Participate in Important Events; We have Socially Significant Partners; We are the Best; We Support the City, the Region, and the Country, etc. The communicative intention to create an image of a successful university determined the choice of lexical units used in the propositional frame to explicate the objective mode and implicate the subjective one.
Encoder-Decoder with Atrous Spatial Pyramid Pooling for Left Ventricle Segmentation in Echocardiography
Authors: Azizi Fityan , Ramadhan Mgs M Luthfi , Jatmiko Wisnu
Published: April 2024

Assessment of cardiac function using echocardiography is an essential and widely used method. Assessment by manually labeling the left ventricle area can generally be time-consuming, error-prone, and has interobserver variability. Thus, automatic delineation of the left ventricle area is necessary so that the assessment can be carried out effectively and efficiently. In this study, encoder-decoder based deep learning model for left ventricle segmentation in echocardiography was developed using the effective CNN U-Net encoder and combined with the deeplabv3+ decoder which has efficient performance and is able to produce sharper and more accurate segmentation results. Furthermore, the Atrous Spatial Pyramid Pooling module were added to the encoder to improve feature extraction. Tested on the Echonet-Dynamic dataset, the proposed model gives better results than the U-Net, DeeplabV3+, and DeeplabV3 models by producing a dice similarity coefficient of 92.87%. The experimental results show that combining the U-Net encoder and DeeplabV3+ decoder is able to provide increased performance compared to previous studies.
A Dynamic-Bayesian-Network-Based Approach to Predict Immediate Future Action of an Intelligent Agent
Authors: Kridalukmana Rinta , Eridani Dania , Septiana Risma
Published: April 2024

Predicting immediate future actions taken by an intelligent agent is considered an essential problem inhuman-autonomy teaming (HAT) in many fields, such as industries and transportation, particularly toimprove human comprehension of the agent as their non-human counterpart. Moreover, the results of suchpredictions can shorten the human response time to gain control back from their non-human counterpartwhen it is required. An example case of HAT that can be benefitted from the action predictor is partiallyautomated driving with the autopilot agent as the intelligent agent. Hence, this research aims to develop anapproach to predict the immediate future actions of an intelligent agent with partially automated drivingas the experimental case. The proposed approach relies on a machine learning method called naive Bayesto develop an action classifier, and the Dynamic Bayesian Network (DBN) as the action predictor. Theautonomous driving simulation software called Carla is used for the simulation. The results show that theproposed approach is applicable to predict an intelligent agent’s three-second time-window immediate futureaction.