bluuebunny/crossref_metadata_2025 huggingface dataset:
Dikdörtgensel Engellerin Dairesel Oluklu bir Kanalın Isıl-Hidrolik Özellikleri Üzerindeki Etkilerinin Sayısal Olarak İncelenmesi
Authors: KOCA Ferhat , GÜRLEK Cahit
Published: October 2023

Bu çalışmada dairesel oluklu bir kanalın alt yüzeyine farklı açılar ve yüksekliklerde yerleştirilen dikdörtgensel engellerin kanalın ısıl-hidrolik özelliklerine olan etkisi sayısal olarak incelenmiştir. Analizler için 500x10 mm boyutlarında üç bölümden oluşan (yukarı akış, oluklu ve aşağı akış) bir kanal kullanılmıştır. Engeller kanal yüzeyine üç farklı açı (β=45°, 90° ve 135°) ve üç farklı yükseklikte (h/H=0,1, 0,25 ve 0,5) yerleştirilmiştir. Süreklilik, momentum ve enerji denklemlerinin çözümleri k-ε türbülans modeli kullanılarak Ansys-Fluent sonlu hacimler yöntemi ile gerçekleştirilmiştir. Akış alanına ait türbülans kinetik enerji (TKE) konturları ile ortalama Nusselt sayısı (Nu), sürtünme faktörü (f), basınç düşüşü (ΔP) ve performans değerlendirme kıstas sayısı (PEC) değerleri Reynolds sayısının (Re) 5000-20000 aralığı için elde edilmiştir. En yüksek termal-hidrolik performans h/H=0,1, β=45° kanal modeli için elde edilmiştir. Bu durum PEC değerlerine göre en düşük performansa sahip h/H=0,5, β=135° modele kıyasla %26,19 daha fazladır.
Combination of Conventional Ball Mill and Stirred Mill to Obtain Ultra-Fine Talc
Authors: GÜLEÇ Ömer , TORAMAN Öner Yusuf , UÇURUM Metin
Published: October 2023

In this study, it was investigated that talc ore could ground to very fine sizes using a combination of conventional ball mill and vertical stirred mill. Firstly, the conventional ball mill parameters such as mill speed (% of critical speed), material filling ratio (Jb), ball filling ratio (fc), ball size distribution (10-20-30-40 mm, %), grinding aid ratio (% of powder) and grinding time (min.) were optimized using classic experimental design. As a result of the optimization, fine talc product was obtained with d90=93.52 µm particle size. In the second stage, the ball mill product was re-milled using a stirred mill. As a result of study, a final ultra-fine talc powder was obtained after 60 minutes grinding time with d50=1.85 µm particle size and 14058 cm2/g total surface area. It has been seen that the conventional ball mill+stirred mill combination effective a process to obtain talc powder that suitable for industrial use.
The Effects of Repeated Laundering and Structural Parameters on the Terry Fabric Preference of Japanese Consumers and Comparison with Turkish Consumers
Authors: KALAYCI Ece , ALA Deniz Mutlu , TOPÇU Hüseyin , SATO Tetsuya , İKİZ Yüksel
Published: October 2023

The objective of this research is to determine the effects of weft yarn count, weft density and repeated laundering effects on terry fabric preference of Japanese participants and to compare with the preferences of Turkish participants. In addition, the terry fabric samples are evaluated by Japanese panelists in order to determine the importance of characteristics related to preference. Terry samples woven with nine different constructions are subjected to 5, 10, 20 and 40 washing cycles in a household washing machine before subjective evaluations. The subjective evaluations are performed in two steps with a total of 40 Japanese volunteers consisting 20 men and 20 women at the ages of 18-25 years. Both Japanese and Turkish participants preferred terry fabric samples woven with finer weft yarns at a higher rate. The preference rate for terry fabrics decreased with increasing washings cycles among the participants of both countries. In addition, the most important characteristics related to preference of Japanese participants has been revealed.
Sitrik Asit ve TiO2 Nanoparçacık Karışımlarının Yünlü Kumaşların Sararma ve Katlanma Açısına Etkisinin İncelenmesi
Authors: SEZGİN BOZOK Sabiha , OĞULATA Tuğrul
Published: October 2023

Sitrik asit (C6H8O7) tekstil yüzeyleri için çapraz bağlayıcı olarak kullanılabilen çevre dostu, insan sağlığına zararı olmayan, maliyeti düşük bir tür karboksilik asittir. Titanyum dioksit (TiO2) nanoparçacıklar (NP) ise geniş yüzey alanı ile uygulandığı ürüne kendi kendini temizleyebilme, UV bloklama, vs gibi birçok fonksiyonel özellik kazandırabilen beyaz renkte pigmenttir. Sitrik asitin kumaşlarda buruşmazlık özelliğini arttırması gibi fayda sağladığı önceki çalışmalarda görülmüştür ancak bu kimyasalın tekstil yüzeylerine uygulanması sonucunda ürünü sarartma gibi bir dezavantajı bulunmaktadır. Bu çalışmada renksiz yünlü kumaşlar için TiO2 NP süspansiyonları hazırlanmış ve farklı konsantrasyonlarda sitrik asitle karıştırılmıştır. Emdirme-kurutma-termofiksaj yöntemi ile kumaşlara aplike edilmiştir. Taramalı elektron mikroskobu (SEM) analizi ile TiO2 süspansiyonu katkılı sitrik asitin lif yüzeyini değiştirdiği tespit edilmiştir. Sitrik asitle yünlü numunelerde sararma görülmüş ancak çözeltilere TiO2 NP ilave edildiğinde numunelerdeki sararma oldukça azalmıştır. 15 gr/L sitrik asitle işlem gören yünlü numunelerin hem atkı hem çözgü yönünde katlanma açısı 4° arttırılabilmiştir, bu konsantrasyonda sitrik asit çözeltisine ilave edilen TiO2 NP ile numunelerin katlanma açısı düşmüş ancak işlem görmemiş numuneye göre yüksek çıkmıştır.
Panoramik Diş Görüntülerinde Derin Evrişimsel Sinir Ağına Dayalı Gömülü Diş Tespiti ve Segmentasyonu
Authors: DURMUŞ Meryem , ERGEN Burhan , ÇELEBİ Adalet , TÜRKOĞLU Muammer
Published: October 2023

Gömülü diş tespiti, diş hekimliği uygulamalarında önemli bir adımdır ve doğru bir tespit süreci, tedavi planlaması ve teşhislerde büyük önem taşır. Geleneksel yöntemlerin sınırlamaları ve hata olasılıkları göz önüne alındığında, derin öğrenme modelleri gibi yapay zekâ temelli yaklaşımların kullanılması giderek daha yaygın hale gelmektedir. Bu çalışmada panoramik gömülü diş görüntülerinde derin öğrenme modellerinin performansı incelenmiştir Yedi farklı modelin (VGG16-Unet, VGG19-Unet, MobileNetV2, Unet-v1, Unet-v2, Unet-v3 ve Unet-v4) performansı değerlendirilmiştir. VGG16-Unet modelinin AUC (eğri altındaki alan) değeri %94.87 ile diğer modellere kıyasla daha yüksek bulunmuştur. Bu çalışma, diş hekimliği alanında daha doğru ve hassas segmentasyon yöntemleri geliştirilmesine katkı sağlayarak, diş tespiti ve tedavi planlaması süreçlerinde daha güvenilir sonuçlar elde edilmesini desteklemektedir.
Comparison of a Dynamic Model of Electric Arc Furnace with Actual Operation Data for Voltage Flicker Analysis in Electrical Power Network
Authors: KÖROĞLU Tahsin
Published: October 2023

Electric arc furnaces (EAFs) used in the iron and steel manufacturing industry for melting and reﬁning scrap metals are one of the most disturbing loads that exhibit unbalanced and highly nonlinear characteristics. Serious voltage fluctuations occur in the power system as a result of the rapid change in the current drawn from the grid by the EAF. Voltage fluctuations lead to a power quality problem known as flicker, which is defined as observable changes in light sources that affect the production environment, cause eye fatigue in personnel, and lower the work concentration levels. To investigate the voltage flicker problem, an accurate mathematical model describing the behavior of the EAF load is required. In this study, a dynamic EAF model that can be adjusted to different operating conditions has been developed in the time domain. The electric arc voltage has been modeled as an externally controllable voltage source. The instantaneous arc voltage has been expressed as a function of the arc length independent of the current. The arc resistance, which varies with time and is nonlinear, has also been calculated with differential equations using the instantaneous arc voltage value. To measure the short-term flicker severity index caused by the EAF in the power system, a flicker meter in compliance with the International Electrotechnical Commission (IEC) 61000-4-15 standard has been designed. The current-voltage characteristics of the EAF, its effect on the power system, and the flicker severity occurring at the point of common coupling (PCC) have been analyzed with simulation studies using the PSCAD/EMTDC software. Besides, the simulation results of the dynamic model of the EAF have been compared with the results obtained from the model based on the measured ﬁeld data.
Music Genre Recognition Based on Hybrid Feature Vector with Machine Learning Methods
Authors: HIZLISOY Serhat , ARSLAN Recep Sinan , ÇOLAKOĞLU Emel
Published: October 2023

Music genre recognition is one of the main problems in infotainment tools and music streaming service providers for different tasks such as music selection, classification, recommendation, and personal list creation. Automatic genre recognition systems can be useful for different music-based systems, especially different music platforms. Therefore, this study aimed to classify music genres using machine learning. In this context, GTZAN dataset consisting of 10 classes was used. In this dataset, data augmentation was applied by segmentation. Each record of 30 seconds was divided into 10 parts, increasing the number of samples in the dataset by a factor of 10. Then, features were extracted from the audio signals. The resulting features are chroma, harmony, mel frequency cepstral coefficients, perceptr, root mean square, roll-off, spectral centroid, tempo, and zero crossing rate. The types, variances, and averages of the obtained features were used. Thus, 57 features were obtained. This feature set was pre-processed by delimiting the decimal part, standardization, and label encoding. In the last step, classification was made with different machine learning methods and the results were compared. As a result of hyperparameter optimization in the Extra Tree model, 92.3% performance was achieved. Precision recall and f-score values are 92.4%, 92.3%, and 92.3%, respectively. As a result, an efficient and high-performance model in music genre recognition was created.
Çözelti Konsantrasyonu ile Nanolif Çapı Arasındaki İlişki
Authors: ŞİMŞEK GÜNDÜZ Gonca
Published: October 2023

İki farklı polimer kullanılarak değişik konsantrasyonlarda çözeltilerden elektrolif çekim yöntemi ile üretilen liflerin morfolojisi incelenmiştir. Bu amaçla poliakrilonitril (PAN) polimeri, dimetilformamid (DMF) çözeltisinde %9, %12, %15 ve %18 konsantrasyonlarda olacak şekilde çözülmüştür. Polivinilalkol (PVA) polimeri suda çözülerek %12, %14, %16 konsantrasyonlarda çözeltiler hazırlanmıştır. %18 PAN çözeltisi ile nano lif üretimi gerçekleşmemiştir. Diğer konsantrasyonlarda her iki polimerle nanolif üretimi gerçekleştirilmiştir. Konsantrasyon değeri arttıkça boncuk oluşumunda azalma gözlenmiştir. Nanoliflerin çapları taramalı elektron mikroskobuyla (SEM) ölçülmüştür. Analizler için SPSS programı kullanılmıştır. Daha önceki çalışmalardan farklı olarak bu çalışmada PAN nanoliflerinin siyah kâğıt yüzeyindeki görünümleri incelenmiştir. PAN çözeltisinde konsantrasyon %9 değerinden %12’ye yükseldiğinde lif çapları artarken, konsantrasyon %12’den %15’e yükseldiğinde meydana gelen artışın istatistiki olarak anlamlı olmadığı görülmüştür. PVA çözeltisinde konsantrasyon arttıkça lif çaplarının istatistiksel olarak arttığı görülmüştür. PAN nanolif ağ tabakalarının kâğıt yüzeyindeki görünümleri karşılaştırıldığında çözelti konsantrasyonunun lif dizilimi ve lifler arası boşluk gibi morfolojik özelikleri etkilediği gözlenmiştir.
Skin Cancer Recognition Using Compact Deep Convolutional Neural Network
Authors: BALLA FOFANAH Alhaji , ÖZBİLGE Emre , KIRSAL Yonal
Published: October 2023

Skin cancer is a common form of cancer that affects millions of people worldwide. Early detection and accurate diagnosis of skin cancer are crucial for effective treatment and management of the disease. There has been a growing interest in using deep learning techniques and computer vision algorithms to develop automated skin cancer detection systems in recent years. Among these techniques, convolutional neural networks (CNN) have shown remarkable performance in detecting and classifying skin lesions. This paper presents a comprehensive study using CNN and deep learning techniques for skin cancer detection using the International Skin Imaging Collaboration (ISIC) dataset. The proposed architecture is a compact deep CNN that is trained using a dataset of benign and malignant skin lesion images. The proposed architecture has achieved 84.8% accuracy, 83.8% TPR, 83.7% TNR, 81.6% F1-score and 80.5% precision for performance evaluation. The experimental results show promising results for the accurate and efficient detection of skin cancer, which has the potential to improve the diagnosis and treatment of this life-threatening disease.
Prioritizing forest patches to enhance habitat restoration and connectivity for the endangered saproxylic beetle Rosalia alpina (Coleoptera, Cerambycidae): a modelling approach.
Authors: Fernández-García José María , Sesma Javier , Moreno Eugenio , Mugarza Valentín
Published: October 2023

The cerambycid beetle Rosalia alpinais associated with temperate, broadleaved (mainly beech) forests containing dead or decaying wood. This species is protected under the Habitats Directive of the European Union. Given its narrow ecological niche and limited dispersal abilities, habitat fragmentation is a conservation concern for populations of R. alpina. In order to maximise the effectiveness of habitat restoration, a scientifically sound procedure for patch selection is needed. In Gipuzkoa (N Spain), we used Light Detection and Ranging (LiDAR) images to search for 20x20-m cells matching the parameterisation of a predictive and local habitat model for R. alpinaat the tree level. The cells selected under quantitative criteria were clustered to identify potential habitat patches. Conefor Sensinode software was used to estimate the importance of each of those patches in terms of the connectivity of the population, based on dispersal distances of R. alpinaand the probabilities of dispersing events among patches. We identified 380 potential habitat patches, mostly in the south-eastern sector of the study area, which were classified into “core areas” and “connecting areas”. The performance of the model was tested in the field (61% of correct assignations), although the actual occurrence of R. alpinawithin the habitat patches should be assessed in the future. This model represents a step forward in guiding the cost-effective implementation of conservation activities, through a strict preservation of the current core habitat patches and an increase in the size of connecting patches.Therefore, we show that connectivity models combining remote sensing data and local habitat selection can be an aid in conservation planning and restoration actions, probably outperforming less efficient strategies, such as random or expert selection.
Principles of correctional and developmental work of a teacher-psychologist with children and adolescents with mild mental retardation.
Authors: Levchenko Anastasiia Anatol'evna
Published: October 2023

Abstract: this article addresses the issue of psychological support for children and adolescents with mild mental retardation on the basis of a general education organization, the need to maintain structure in interaction with this age category.
Öğretmen Adaylarının Öğretmenlik Kariyer Basamaklarına İlişkin Görüşleri Üzerine Bir İnceleme
Authors: YÜCEL Fatma Hümeyra
Published: October 2023

Öğretmenlik kariyer basamakları sistemi 2022 yılında “Öğretmenlik Meslek Kanunu” ile yürürlüğe girmiştir. Bu uygulama ile belirli kriterleri sağlayan öğretmenler “uzman öğretmen” ve “başöğretmen” biçiminde kariyerlerinde ilerleme sağlamaktadır. Hazırlanan çalışmada ise öğretmenlik mesleğine yönelik yetiştirmenin lisanstan itibaren profesyonel biçimde gerçekleştirilmesi göz önünde bulundurulmuş ve öğretmen adaylarının kariyer gelişimlerine yönelik görüşlerin belirlenmesi amaçlanmıştır. Bu bağlamda araştırmada öğretmenlik kariyer basamaklarına yönelik güncel gelişmelerin incelenmesi ve genel eğilimlerin araştırılması öncelenmiştir. Çalışma nitel araştırma yöntemine uygun biçimde hazırlanmıştır. Aynı zamanda durumsal çalışma şeklinde desenlenmiş, verilerin analizi içerik analizi yoluyla gerçekleştirilmiştir. Araştırmanın katılımcıları öğretmen adayları olarak belirlenmiş ve veriler 67 öğretmen adayından elde edilmiştir. Çalışmada 6 farklı soruyu içeren yarı yapılandırılmış görüşme formu kullanılmıştır. Verilerin çözümlenmesinde “frekans” tekniği ile “doğrudan alıntılama” yöntemi uygulanmıştır. Araştırma sonuçlarına göre öğretmenlik kariyer basamakları “olumsuz” ve “olumlu” şeklinde değerlendirilmiştir. Öğretmen adayları tarafından mesleğe atanmada “psikometrik testler” ve “eğitim fakültesi mezunu olmak” kriterleri daha fazla ön plana çıkmıştır. Öğretmenlerin kariyer basamakları içinse niteliksel gelişmelerinin artırılması gerektiği ifade edilmiş, “yazılı sınav” ve “mülakat” kriterleri daha yüksek düzeyde beyan edilmiştir
Design, Synthesis, Molecular Docking and Cytotoxicity of Stilbene-arylcinnamide
Hybrids on A549 Lung Cancer Cells
Authors: Zaki Nurain Syazwani Mohd. , Mohamad Kamal Nik Nur Syazni Nik , Supratman Unang , Harneti Desi , Hassan Mohd. Zaheen , Mohamad Taib Mohamad Nurul Azmi
Published: October 2023

A new series of stilbene-arylcinnamide hybrids have been designed and synthesized with various
substituents. These compounds were characterized by FTIR, 1D- and 2D-NMR as well as mass spectroscopy
analysis (HRESIMS). The synthesized compounds were tested for their cytotoxic activity against human lung
cancer A549 cell. The most active compound was further studied via in silico molecular docking on α,β-
interface of tubulin. Total 18 new stilbene-arylcinnamide hybrids have been synthesized with 42-80% yield
and evaluated for their cytotoxic activity against human lung cancer A549 cell. Particularly, compound 6b exhibited
potent cytotoxicity against A549 cells with the IC50 value of 19.9 μM. In addition, compound 7b displayed
moderate activities with the IC50 value of 33.9 μM, while other hybrids were considered inactive. Structural
activity relationship (SAR) studies revealed that the presence of an isopropyl group at the para position on
ring A and a methyl group at the para position on ring C is beneficial for enhanced cytotoxicity. Furthermore,
we also developed an in silico molecular docking to study the binding interaction of the active compounds to
the α,β-interface of tubulin (PDB ID: 3E22). Hybrids 6b and 7b demonstrated promising binding interactions
and affinities into the tubulin active site with calculated binding energy of -7.2 and -8.0 kcal/mol, respectively.
Nano-approaches and Recent Advancements in Strategies to Combat
Challenges Associated with Thyroid Cancer Therapies
Authors: Singh Gurmehar , Rathee Jatin , Triveni  , Jain Neha , Nagaich Upendra , Kaul Shreya , Pandey Manisha , Gorain Bapi
Published: October 2023

The prevalence of thyroid cancer (TC) is more common in women and is up to 43% in patients aged between 45-65 years. The battle against TC is hampered by the lack of effective diagnostic
and therapeutic approaches. The effectiveness of surgical procedures, such as thyroidectomy and
nutraceutical treatments, are accompanied by several difficulties and still require further research. Alternatively, the DNA-damaging traditional model of chemotherapy is linked to poor solubility, untoward systemic effects, and associated cytotoxicity, instituting an urgent need to establish a specialized, factual, and reliable delivery tool. In order to overcome the limitations of conventional delivery
systems, nanotechnology-based delivery tools have shown the potential of articulating endless inherent implementations. The probable benefits of emerging nanotechnology-based diagnostic techniques
include rapid screening and early illness diagnosis, which draws investigators to investigate and assess
the possibility of this treatment for TC. Subsequently, organic (e.g., liposomes, polymer-based, and
dendrimers) and inorganic (e.g., gold, carbon-based, mesoporous silica, magnetic, and quantum dots)
NPs and hybrids thereof (liposome-silica, chitosan-carbon, and cell membrane-coated) have been projected for TC biomarker screening, therapy, and detection, providing better outcomes than traditional
diagnostic and treatment techniques. Therefore, this review aims to offer a broad perspective on nanoplatform in TC, accompanied by present and potential future treatment options and screening techniques. The goal of cancer therapy has traditionally been to "search a thorn in a hayloft"; therefore,
this article raises the possibility of treating TC using nano-oncotherapeutics, which might be useful
clinically and will encourage future researchers to explore this tool’s potential and drawbacks.
Risk analysis of material management that causes cost and time deviations in high-story building projects
Authors: Wibawa I Gede Sastra , Santiana I Made Anom , Suasira I Wayan , Sudiasa I Wayan , Sumardika A A N Roy
Published: October 2023

Construction Work Project for Maternal and Child Health Services Building of RSUP Prof. Dr. IGN. Ngoerah Denpasar Bali is a multi-storey building project that has an area of 18,226 m2 which is targeted for completion on November 27, 2023. To get the time to complete the work on time, it is necessary to anticipate various risks that occur, one of which is the risk of material management during project construction. From the research to be carried out, material management risks that affect time delays and cost deviations in the project will be identified using the AHP (Analytic Hierarchy Process) method. This study will identify the level of risk or risk index that most dominantly affects time delays and cost deviations. The most dominant material management risks that have been identified will then be mitigated to reduce the identified dominant risks. Based on the results of the analysis, 30 risk variables were identified for cost performance and 34 risk variables were identified for time performance.
Pielęgnowanie pacjenta w chorobie wrzodowej żołądka i dwunastnicy
Authors: Duda Emilia
Published: October 2023

Wstęp. Choroba wrzodowa żołądka i dwunastnicy ma charakter przewlekły i może prowadzić do poważnych powikłań, w tym zagrażających życiu.

Cel. Celem pracy była analiza zadań pielęgniarki w opiece nad pacjentem z chorobą wrzodową żołądka i dwunastnicy.

Prezentacja przypadku. Pacjent lat 44 przyjęty w trybie nagłym do szpitala na SOR z powodu krwawienia z górnego odcinka przewodu pokarmowego i bólu w klatce piersiowej. Tydzień temu pacjent zakończył ciąg alkoholowy. Po badaniu gastroskopowym potwierdzono wrzód żołądka i dwunastnicy oraz krwawienie z pękniętego wrzodu. Podjęto decyzję o operacji w trybie pilnym. Obecnie 1 doba pobytu chorego w oddziale chirurgii.

Wnioski. Problemy pacjenta z chorobą wrzodową żołądka i dwunastnicy są wyzwaniem dla chorego, jak i dla całego zespołu terapeutycznego sprawującego nad nim opiekę. Dominującymi problemami u chorego są: ryzyko wystąpienia ponownego krwotoku z przewodu pokarmowego, możliwość wystąpienia zaburzeń wodno-elektrolitowych, ryzyko zakażenia i rozejścia się brzegów rany po operacji, ból w okolicy rany, ryzyko wystąpienia powikłań układu oddechowego i pokarmowego po operacji, złe samopoczucie pacjenta z powodu nudności, deficyt samoopieki ze strony pacjenta, ryzyko wystąpienia niedożywienia u chorego, niepokój pacjenta o swój stan zdrowia, brak wiedzy na temat uwarunkowań choroby wrzodowej i jej związku  z alkoholizmem.

Działania edukacyjne podejmowane przez pielęgniarkę wobec pacjenta z chorobą wrzodową żołądka i dwunastnicy w dążeniu do profilaktyki powikłań choroby i występowania jej zaostrzeń powinny koncentrować się na: motywowaniu do zmiany dotychczasowego stylu życia, rezygnacji z palenia tytoniu i zaprzestania picia alkoholu, stosowaniu się zasad samokontroli i terapii, w tym dietoterapii.
OPTIMIZATION OF PRIMARY PREVENTION MEANS OF ORAL TISSUES DISEASES IN MILITARY PERSONNEL OF THE ARMED FORCES OF UKRAINE
Authors: Lavrin O.Ya.
Published: October 2023

Резюме. Специфічні умови життя і бойової діяльності особового складу Збройних Сил України, пов’язані з особливостями військової професії, мають вплив на перебіг патологічних процесів зубощелепного апарату, потребують відповідних методів профілактики та лікування.

 

Тому метою даної роботи став аналіз результатів впровадження програми первинної профілактики захворювань тканин ротової порожнини у військовослужбовців Збройних Сил України, яка оптимально була б використана в умовах проведення бойових дій.

 

Методи. Для оцінки стоматологічного статусу пацієнтів проведено клінічне стоматологічне обстеження 348 військовослужбовців віком 20-45 років. Гігієнічний стан ротової порожнини оцінювали за допомогою гігієнічних індексів J.C. Green, J.R. Vermillion (ОНІ-S), Федорова-Володкіної, АРІ. Всім пацієнтам надано рекомендації щодо догляду за ротовою порожниною на період ротації згідно індивідуально розробленої програми. Контрольні відвідування проводили через 3, 6, 9 та 12 місяців.

 

Результати дослідження. Під час первинного огляду у військовослужбовців 20-25 р. та 26-30 р. стан гігієни ротової порожнини відповідає задовільному рівню. У вікових групах 30-35, 36-40 та 41-45 р. відмічається поганий та незадовільний рівень гігієни згідно вказаних індексів. Через 6 місяців використання запропонованої програми первинної профілактики гігієнічний стан ротової порожнини обстежених покращився у всіх вікових групах. Через 12 місяців спостереження у обстежених вікових груп 20-25, 26-30, 31-35, 36-40 р. відмічали хороший рівень гігієни згідно вказаних індексів. Проте у віковій групі 41-45 р. констатовано задовільний рівень гігієни згідно індексів ОНІ- S та Федорова-Володкіної.

 

Висновок. Отже, можна зробити висновок, що під час планування заходів первинної профілактики захворювань тканин ротової порожнини необхідно враховувати особливості побуту пацієнтів, що особливо доцільним є у військовослужбовців, які перебувають в зоні проведення бойових дій.
Retrospective Study On Cystic Echinococcosis in Livestock in Northern Türkiye
Authors: Dal Ayşe Gül , TERZİ Funda , DAL FatmaNur , PEHLİVAN Şakir , TÜRLEK Şakir Önder , Kaya Selma , ÇIBIK Recep
Published: October 2023

Objective. This study was conducted retrospectively to assess the cystic echinococcosis status of farm animals from the samples sent to Samsun Veterinary Control Institute of the Republic of Türkiye, Ministry of Agriculture and Forestry, between January 2016 and December 2022. Materials and Methods. A total of 818 sheep, 160 goats, and 990 cattle necropsy materials were examined macroscopically and histopathologically according to World Organisation for Animal Health (WOAH) guidelines. Cysts were detected in 61 of examined materials. Results. The rate of total cystic echinococcosis positivity in farm animals was found to be 3.1% in northern Türkiye. Cysts were detected in at least one of the liver and lungs. It was detected in the liver in 24 cases (39.3%), the lung in 23 cases (37.7%), and both the lung and liver in 11 cases (18%). In addition, cysts were found in both of lung and spleen (1 case), kidney and liver (1 case), and heart and liver (1 case). The positivity rate was higher in sheep than in other ruminants, and the difference with other ruminant species was statistically significant. (p<0.001). The difference between prevalence rates by years was found to be statistically significant (p=0.001). Conclusions. Türkiye is defined as a highly endemic region for Echinococcus granulosus and Echinococcus multilocularis. Surveillance should be done regularly to implement control programs. The information presented in this study will contribute to gaining an idea about the status of cystic echinococcosis in livestock in northern Türkiye and to the development of prevention and control strategies.
EDUCAÇÃO INCLUSIVA, INTERDISCIPLINARIDADE E TEORIA DA APRENDIZAGEM SIGNIFICATIVA
Authors: Felicetti Suelen Aparecida , Batista Irinéa de Lourdes
Published: October 2023

Devemos oportunizar que professores atuantes na Educação Básica e formadores de professores vivenciem formação inicial e em serviço que facilite consolidar saberes e constituir identidades profissionais. Dentre os saberes necessários, estão os referentes à Educação Inclusiva (EI), Interdisciplinaridade e Teoria da Aprendizagem Significativa (TAS). Assim, partimos da questão: como relacionar tais referenciais, evidenciando pontos em comum enriquecedores do campo teórico epistemológico e da formação de professores de Biologia? Objetivamos propor e discutir relações convergentes entre EI, Interdisciplinaridade e TAS, construtivas do ponto de vista teórico epistemológico e potenciais para embasar formação reflexiva em Biologia. Realizamos um estudo, analisando à luz dos três referenciais, os seguintes pontos: concepção de conhecimento, objetivo do ensino, noções de aprendizagem, influência do contexto e papel dos professores. Percebemos que existe complementaridade e as discussões se tornam mais ricas e completas por meio desta articulação.
REFLEXÕES SOBRE AS (IM)POSSIBILIDADES DE DIÁLOGO ENTRE ESTÁGIOS SUPERVISIONADOS E PROGRAMAS DE INICIAÇÃO À DOCÊNCIA
Authors: Pereira da Silva João , André da Silva Costa Elisangela , Da Silva Ribeiro Leite Maria Cleide , De Brito Anselmo Katyanna
Published: October 2023

O presente estudo objetiva refletir sobre os limites e as possibilidades de diálogo entre o Estágio Curricular Supervisionado, o Programa Institucional de Bolsas de Iniciação à Docência – PIBID e o Programa Residência Pedagógica – PRP no Instituto Federal de Educação, Ciências e Tecnologia do Ceará e na Universidade Estadual do Piauí, localizadas no nordeste brasileiro. Com enfoque qualitativo, no âmbito da pesquisa narrativa escrita, utilizamos Cartas Pedagógicas como estratégia de aproximação com a realidade. A pesquisa traz reflexões acerca da experiência com o Estágio, PIBID e PRP de docentes que atuaram na coordenação desses subprojetos. Os resultados da pesquisa apontam o estágio e programas de iniciação à docência essenciais na formação docente, todavia, atravessados pela perspectiva de uma educação mercadológica. Sobre as possibilidades, percebe-se a necessidade de construção e fortalecimento de articulações pedagógicas entre estágio e os programas supracitados.
APRENDIZAGEM SIGNIFICATIVA E COLABORATIVA NA CONTABILIDADE
Authors: Nadielli Maria dos Santos Galvão  , Nou Schneider Henrique
Published: October 2023

O objetivo deste estudo é identificar aspectos que possam potencializar a Aprendizagem Significativa e Colaborativa no curso de Ciências Contábeis. Assim, realizou-se uma pesquisa do tipo Estado do Conhecimento, na base La Referencia, buscando por teses e dissertações. Como resultado, percebemos que, para o fortalecimento da aprendizagem colaborativa e significativa, torna-se necessário garantir o comprometimento do estudante e a adoção de práticas pedagógicas diferenciadas. Valendo-se das metodologias ativas e de recursos digitais, o professor poderá perceber no seu estudante mais motivação, predisposição para estudar e o desenvolvimento de habilidades cognitivas e sociais, possibilitando a formação de um profissional contábil completo. Nesse sentido, o trabalho proporciona uma visão ampla dos estudos que estão sendo realizados sobre a temática da aprendizagem significativa e colaborativa em um curso de graduação específico, em uma região geoeconômica pouco explorada em pesquisas de revisão da literatura.
Clinical Decision Support to Reduce Opioid Prescriptions for Dental Extractions using SMART on FHIR: Implementation Report
Authors: Rindal D Brad , Pasumarthi Dhavan Prasad , Thirumalai Vijayakumar , Truitt Anjali R , Asche Stephen E , Worley Donald C , Kane Sheryl M , Gryczynski Jan , Mitchell Shannon G
Published: October 2023

Background

Clinical decision support (CDS) has the potential to improve clinical decision-making consistent with evidence-based care. CDS can be designed to save health care providers time and help them provide safe and personalized analgesic prescribing.

Objective

The aim of this report is to describe the development of a CDS system designed to provide dentists with personalized pain management recommendations to reduce opioid prescribing following extractions. The use of CDS is also examined.

Methods

This study was conducted in HealthPartners, which uses an electronic health record (EHR) system that integrates both medical and dental information upon which the CDS application was developed based on SMART (Substitutable Medical Applications and Reusable Technologies) on FHIR (Fast Healthcare Interoperability Resources). The various tools used to bring relevant medical conditions, medications, patient history, and other relevant data into the CDS interface are described. The CDS application runs a drug interaction algorithm developed by our organization and provides patient-specific recommendations. The CDS included access to the state Prescription Monitoring Program database.

Implementation (Results)

The pain management CDS was implemented as part of a study examining opioid prescribing among patients undergoing dental extraction procedures from February 17, 2020, to May 14, 2021. Provider-level use of CDS at extraction encounters ranged from 0% to 87.4% with 12.1% of providers opening the CDS for no encounters, 39.4% opening the CDS for 1%-20% of encounters, 36.4% opening it for 21%-50% of encounters, and 12.1% opening it for 51%-87% of encounters.

Conclusions

The pain management CDS is an EHR-embedded, provider-facing tool to help dentists make personalized pain management recommendations following dental extractions. The SMART on FHIR–based pain management CDS adapted well to the point-of-care dental setting and led to the design of a scalable CDS tool that is EHR vendor agnostic.

Trial Registration

ClinicalTrials.gov NCT03584789; https://clinicaltrials.gov/study/NCT03584789
Online Support Groups for Family Caregivers: Scoping Review
Authors: Daynes-Kearney Rosemary , Gallagher Stephen
Published: October 2023

Background

Caregiving can affect people of all ages and can have significant negative health impacts on family caregivers themselves. Research has shown that social support acts as a buffer against many negative health impacts. A common source of social support is support groups. Although traditionally, these groups were conducted in a face-to-face setting, the advent of the internet, social media applications, and the smartphone have seen online support groups (OSGs) develop as a space where many caregivers seek support. The number of OSGs has increased exponentially, but there is no clear consensus on what factors or characteristics of OSGs contribute to social support development within them or what types of OSGs are available to family caregivers.

Objective

This study aimed to conduct a scoping review to contribute to the understanding of the types and characteristics of OSGs for family caregivers.

Methods

Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews guidelines, the CINAHL, PsychInfo, Psych Articles, Social Sciences, Communication Source, Medline, and Web of Science databases were searched for studies (caregiver focused, adults aged 18 years or older, online social support groups, caring for a living person, peer-reviewed journal publications on empirical research). In total, 19 studies were included in the review. The research questions were (1) what type of social support groups are online for adult family caregivers, (2) what the communication mediums and characteristics of these OSGs are, and (3) what psychosocial or other factors make OSGs successful or unsuccessful for participants.

Results

In response to the first research question, we found that the majority of OSGs took place on public text-based forums and were illness specific. Where demographics were reported, participants were predominately women, White, and working with university-level education. There were a variety of caregiving relationships. For the second research question, the most common communication medium found was text-based communication, with the use of emojis, photos, and GIF (Graphics Interchange Format) files as part of these exchanges. Most frequently, the OSGs were asynchronous with a degree of anonymity, not time-limited by the frequency of contact or duration, and moderated by peer or professional moderators or facilitators. Results for the third research question explored the overarching categories of safe communication and engagement and group management. These described successful OSGs as having a focus on similar others with shared lived experiences communicated in a nonjudgmental space overseen by trained peer or professional facilitators.

Conclusions

There are several key considerations for OSGs to be successful for family caregivers. A general recommendation for practitioners is to give importance to building active moderation and multifaceted structures of support to meet different levels of caregiver needs and the ability to engage.
Schizophrenia a Personal Experience
Authors: - Anon
Published: October 2023

None
Exploring Students’ Perceptions on Teachers’ Feedback in the Classroom (A Study of Achham Multiple Campus, Nepal)
Authors: Rawal Shankar Bahadur
Published: October 2023

This study, situated within an interpretivist research framework and conducted at an Achham multiple campus in the Far western province of Nepal, delves into students’ perceptions of teacher feedback and the factors influencing its reception and utilization. Qualitative methods and purposive sampling were used. Twenty participated fourth-year students from distinct classes participated, and a combination of learning notes, semi-structured questions, and in-depth interviews were used to reveal their perspectives on feedback delivery. Thematic and interpretive analyses uncovered that student view teacher feedback as a focused mode of communication, distinguishable from regular classroom interactions, often discerned through cues like personal and task-related objectives. Seeking clarity, students frequently pursued both verbal and written feedback, often through dialogues with teachers. The research underscores the intricate nature of feedback, highlighting students’ recognition of emotional, atmospheric, and expectation-based variables that collectively influence its effectiveness. Implying a need for further exploration into teacher and student feedback expectations, the study also suggests an intriguing avenue of investigation into the role of teacher emotions in shaping feedback. Ultimately, this research enriches our understanding of students’ engagement with teacher feedback, shedding light on the intricate educational dynamics at play.
POSSIBLE INVOLVEMENT OF PEROXIDATIVE STRESS AND ANTIOXIDANT LEVELS IN ALCOHOLIC AND NON-ALCOHOLIC HEALTHY SUBJECTS
Authors: CHOUDHARY URMILA , SINGH HARCHARAN , GUPTA VARSHA
Published: October 2023

Objectives: Antioxidant levels vary from person-to-person depending on their degree and type of activity, food, exposure to psychological stress, and contaminated environment. In addition, those who are older, have specific medical conditions, take drugs, smoke, and consume alcohol, and are exposed to solar radiation may require more carotenoids and other antioxidants. This led us to compare the antioxidant levels within alcoholics and non-alcoholic healthy subjects.
Methods: Malondialdehyde (MDA) and level of some antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione (GSH), antioxidant Vitamin A, Vitamin C, and Vitamin E were estimated in the circulations of alcoholics and non-alcoholic healthy subjects.
Results: Significantly increased concentrations of plasma thiobarbituric acid reactive substances, and significantly lowered levels of SOD, CAT, GSH, and GSH-Px were observed in alcoholics and may be due to their increased utilization to scavenge lipids peroxides. Increased levels of lipid peroxidation may be due to excessive oxidative stress. The comparison between alcoholics and non-alcoholics revealed 24% increased MDA in alcoholic subjects. Enzymatic (SOD, CAT, and GSH-Px), metabolic (GSH), and nutrient antioxidants (Vitamin A, E, C, and β-carotene) were lower in alcoholic as compared to non-alcoholic subjects.
Conclusion: Regardless of commercial brand, alcohol raises oxidative stress. When drinking alcohol and smoking or environmental contamination are coupled, this stress is significantly greater.
EVALUATION OF EFFICACY AND SAFETY OF ORAL VITAMIN D3 AND VITAMIN E AS AN ADD-ON-THERAPY TO METHOTREXATE IN PATIENTS OF MODERATE CHRONIC PLAQUE PSORIASIS
Authors: Narang Garima , RANI SEEMA , KATARIA USHA , BHUTANI GARIMA , SAINI RAHUL
Published: October 2023

Objective: This study was conducted with the aim to evaluate the efficacy and safety of oral Vitamin D3 and Vitamin E as an add-on-therapy to methotrexate (MTX) in patients of moderate chronic plaque psoriasis.
Methods: In this prospective, open-labeled, randomized, and comparative clinical study, a total of 120 patients of age 20–60 years with moderate chronic plaque psoriasis attending the dermatology outpatient department were randomly allocated into three groups of 40 each, i.e., Group M, Group D, and Group E. Group M received MTX (7.5 mg) tablet orally weekly, Group D received MTX (7.5 mg) and Vitamin D3 (60,000 IU) sachet orally weekly, and Group E received MTX (7.5 mg) weekly and Vitamin E (400 mg) daily. Efficacy assessment was done through the following primary parameters-psoriasis area and severity index (PASI) score, dermatology life quality index (DLQI), and psoriasis disability index (PDI), and secondary parameters such as Vitamin D deficiency and insufficiency among the study participants and improvement of serum 25(OH)D concentration. Adverse events were monitored.
Results: PASI and DLQI were calculated at the time of recruitment (baseline), 1 month, 2 months, 3 months, and 4 months, and PDI and serum Vitamin D were calculated at baseline and 4 months. On intergroup comparison of PASI score and PDI, statistically significant results were seen at 4 months. DLQI showed significant results at 2, 3, and 4 months. Significant results were found in Group D which signifies improvement in serum Vitamin D levels. Mild side effects were seen at the end of 4 months.
Conclusion: The present study suggested that Vitamin D as an add-on therapy was found to cause a significant reduction in psoriatic lesions. It could be a promising drug in patients with psoriasis to improve the psoriatic lesions, when combined can reduce the dose of MTX, thereby minimizing the side effects.
A RETROSPECTIVE ANALYSIS OF SPONTANEOUSLY REPORTED ADVERSE DRUG REACTIONS TO ANTIRETROVIRAL THERAPY DURING AND POST-TRANSITIONAL PHASE OF DOLUTEGRAVIR
Authors: SWAROOPA KATIKITALLA , DURGA DEVI PILLA S SURYA , KEERTHANA S , SRINIVASA RAO R
Published: October 2023

Objectives: The main objective of this study was to analyze the pattern of reported adverse drug reaction (ADRs) in people receiving antiretroviral therapy (ART) mainly during and post-transitional phase of dolutegravir-based regimens.
Methods: This is a retrospective observational study initiated after the approval of the Institutional Ethics Committee and from the ART Center. Sources of data are spontaneously reported ADR data of human immunodeficiency virus (HIV) persons to the ADR monitoring center (AMC).
Results: A total of 190 patients who are on ART reported at AMC from April 2020 to June 2022 had a total of 204 ADRs. Among them, 108 (57%) were females and had a higher prevalence than 82 (43%) males. ADRs were higher among the age group of 41–50 years (33.68%) followed by 31–40 years (32.10%). Among dolutegravir-based regimens, tenofovir, lamivudine, and dolutegravir were given to more patients (118). The most common ADRs encountered were peripheral neuropathy 16.66%, followed by hyperglycemia (14.21%), renal toxicity (10.29%), hyperbilirubinemia (9.31%), and anemia (7.84%) of all ADRs.
Conclusion: In this study, it has been observed that HIV patients on dolutegravir-based regimens are associated with more ADRs. Nervous system disorders were the most commonly observed group of ADRs, followed by metabolism and nutritional disorders, the others being skin diseases and renal toxicity. This incidence of ADRs to ART calls for efficient pharmacovigilance surveillance to improve patient care and drug safety.
ELECTROPHYSIOLOGICAL ASSESSMENT OF NERVE CONDUCTION IN DIABETES MELLITUS AND HYPERTENSION PATIENTS OF TERTIARY CARE HOSPITAL OF CENTRAL INDIA
Authors: Dubey Namrata , Kumar Shailesh , Farrukh Ashima , Budholia Prabhat Kumar
Published: October 2023

Objectives: Nerve conduction studies (NCS) are electrophysiological tools used to assess the whole perseverance of the cranial and peripheral nervous systems; consequently, NCS seems to be diagnostically advantageous in the documentation and categorization of disorders concerning nerve roots, peripheral nerves, muscle, and neuromuscular junction, and are often complemented by needle electromyography. Hence, the current research was aimed to evaluate the electrophysiological nerve conduction among cases through diabetes and hypertension (HTN).
Methods: This prospective study was achieved with the cases attending the Department of Physiology, NSCB Medical College, after obtaining ethical clearance from the institution and the consent forms from all the patients, we have enrolled 165 patients on total, which grouped into three groups: Group Diabetes Mellitus [DM] = 55, Group HTN (Hypertension) = 55, and Group DM+ HTN (Diabetes with HTN) = 55. Patients willing to enroll for the study of either sex, of aged between 30 and 79 years with clinical and laboratory evidence of disorder, were included in the study.
Results: The mean duration for DM patients was 7.00±6.99 and for DM+HTN patients was 8.0±5.66 which was observed as statistically significant (p<0.0001). The observed fluctuations in the temperature as well as blood sugar showed statistically significant among the groups (p<0.0001). The variables, namely, median nerve, ulnar nerve, peroneal nerve, tibial nerve, and sural nerve sensory showed statistically significant among the groups (p<0.0001).
Conclusion: The hypertensive cases with diabetes have provocatively abnormal NCV parameters when compared with hypertensive cases without diabetes and cases with diabetes alone.
USE OF PYTHON AND COMPLETE BLOOD COUNT PARAMETERS FOR COST-EFFECTIVE THALASSEMIA SCREENING IN RESOURCE-LIMITED SETTINGS: DEVELOPMENT AND VALIDATION OF A SCREENING PROGRAM.
Authors: Samanta Abhishek , Bhattacharyya Nandan
Published: October 2023

Thalassemia screening is typically done using High-performance liquid chromatography (HPLC), which is an accurate but expensive method that is not widely available. To overcome this issue, researchers have looked into alternative screening methods, such as using erythrocytic indices obtained from a complete blood count (CBC) test. This approach has proven to be highly sensitive and specific, making it an attractive and cost-effective solution for excluding normal populations from thalassemia screening programs. Consequently, it has the potential to improve the efficiency of screening programs, particularly in settings with limited resources.

 A Python program, using the study by Samanta et al. (2021) as a basis, to screen for thalassemia using CBC parameters was created. The program was developed in Python 3.8 using Spyder IDE (Integrated development environment), and it takes in CBC parameters, such as hemoglobin, RBC (Red blood Corpuscles), MCV (mean corpuscular volume), MCH (Mean corpuscular hemoglobin), and HCT (Hematocrit), to determine an individual's thalassemia status. We validated the program using a dataset of 3,000 students who had undergone CBC testing at a local clinic. The dataset was anonymized to ensure privacy protection

Our study showed that the Python program for thalassemia screening based on CBC parameters accurately identified individuals with thalassemia. We validated its performance on a large dataset of students and found that it has the potential to improve screening efficiency and accuracy, particularly in resource-limited settings. However, additional validation studies are necessary to confirm its generalizability and usefulness in diverse populations.