bluuebunny/crossref_metadata_2025 huggingface dataset:
Vybrané instituty římsko-kanonického procesu v praxi pražské konzistoře ve 14. století: exceptiones in ordine iudiciario
Authors: Ondrášková Veronika
Published: November 2023

The article focuses on the legal institute of exceptiones in selected tractates written in the 14th century in the diocese of Prague. The first part introduces Circa processum iudiciarium and its inspirational sources, mainly rooted in William Durand’s Speculum iudiciale. The article also analyses Ordo iudiciarius secundum stilum Pragensem with emphasis on the use and different forms of exceptiones. In addition the submission focuses on other institutes of Roman-Canon law bonded with defences, such as replicationes and interlocutory sentences. Second part of this submission examines the praxis of ecclesiastical courts within the diocese of Prague and their application of selected institutes. Such analysis is conducted based on preserved court files of the General Vicariate as well as judicial charters. The aim of the article is to connect the theoretical concepts of tractates with actual judicial application and usage of these institutes within the Roman-Canon procedure.
Release Proceeding: the Zbiroh Manor Farm Estate in the Years 1670–1690
Authors: Vacek Josef
Published: November 2023

The present paper focuses on the release proceeding of the serfs on the Chamber estates of Točník, Zbiroh and Králův Dvůr in the years 1670–1690, i.e. during the office of the governor Ignatius Sebastian de Bois. The process was controlled by both provincial regulations, such as the Renewed Provincial Ordinance, and overlord regulations, such as the instructions for the governor. However, the exact release proceeding has not yet been described, so the thesis attempts to shed light on the process that both the serfs and the overlords had to undergo in order to issue a letter of release. The thesis concludes with the hypothesis that the mechanisms described are applicable to other chambered estates in the second half of the 17th century. The basis of the thesis are microhistorical probes, which, in conjunction with a quantitative-qualitative approach, allow to capture both the overall picture of the release proceedings and its individual aspects in detail.
Koncepcia spravodlivej vojny v stredovekej a rano-novovekej sociálno-právnej filozofii
Authors: Vyšný Peter , Prudovič Marek
Published: November 2023

The aim of the study is to point out the fact that the evolution of human society is accompanied by constant wars, which demanded a response to its existence also at the level of socio-legal philosophy. It deals with this issue from a legal, moral, and ethical point of view, which, in this case, are basically intertwined in the concept of a just war. Its roots go back to antiquity, and it is also a part of modern war law and philosophy. A relatively significant shift in this concept occurred precisely in the Middle Ages because of Christian wars, or under the influence of medieval teachings. This development continued in the early modern period in connection with the colonization of America. Therefore, in this study, we will focus on the views of Thomas Aquinas (as a representative of the High Middle Ages and scholasticism) and Francisco de Vitoria (as a representative of the Early Modern Age and the School of Salamanca). This topic is even more relevant because nowadays theories of just war are no longer viewed only at the level of a harmless academic debate, but they are beginning to be more and more accentuated as tools serving specific goals of the time.
Omezení sňatků v československých legiích na Rusi a jeho důsledky
Authors: Novák Jakub
Published: November 2023

This paper introduces the specifics of war marriages in the Czechoslovak Legions in Russia during the period of their involvement in the Russian Civil War. After a brief introduction to the historical context, it aims to describe the restrictions imposed on marriages for Czechoslovak legionnaires and their reasons which eventually led to a temporary total ban of war marriages within the Legion for several months after the 1st Convention of Czechoslovak army in the summer of 1918. The paper also explains why and under what conditions the marriages were later re-enabled, what the consequences of marrying without permission were and what legal means the army used to combat high numbers of illegal marriages within its ranks.
Středověké a raně novověké soudnictví na XII. sjezdu českých historiků
Authors: Starý Marek
Published: November 2023

Conference report
An eco-epidemiological model with predator switching behavior
Authors: Tripathi Deepak , Singh Anuraj
Published: November 2023

Switching mechanism is adopted by predator populations when they are provided with two types of prey: susceptible and infected. In this study, we propose a modification of an eco-epidemiological model with the predator switching mechanism. In the presence of switching behavior, the existence of steady states and their stability have been discussed. The qualitative changes in the proposed model have been observed by the existence of transcritical and Hopf bifurcation. Numerical simulations are performed to support our numerical findings. In the context of species’ survival when disease is present in the system, it gives some theoretical views for eco-managers to understand the dynamics.
Carbon emissions analysis of the pulp molding industry: a comparison of dry-press and wet-press production processes
Authors: Lv Zhisheng , Jiang Shaohong , Wei Lingjun , Sun Hao , Liu Yuhui , Cui Jieyu , Zhang Wanlu
Published: November 2023

An initial carbon emission calculation formula for the pulp molding industry was first proposed in accordance with the calculation guidelines provided by the Intergovernmental Panel on Climate Change (IPCC). The formula was primarily developed by utilizing the greenhouse gas accounting methods used in the pulp and paper industry and the life cycle assessment (LCA) theory. Carbon dioxide emissions coming into being during the production processes of dry-press and wet-press pulp molding were calculated individually, alongside the carbon emission factors throughout the lifecycle of the products. This study also delivers a comparative analysis of pulp molding products and similar cushion packaging materials. Moreover, the findings reveal that during the production phase, particularly in the formative stages of pulp molding, substantial carbon dioxide emissions would be produced, with dry-press pulp molding products exhibiting markedly higher carbon emission factors than their wet-press counterparts. The primary objective of achieving low-carbon transformation for the pulp molding industry was to reduce the carbon emissions caused by the forming process, primarily by improving the forming process and enhancing energy efficiency or utilizing clean energy.
Photocatalytic decomposition of Congo red dye by black paste@TiO2 as an efficient recyclable photocatalyst
Authors: Ghoniem Monira Galal , Ben Aissa Mohamed Ali , Adam Fatima A. , Daoush Walid M. , Khairy Mohamed
Published: November 2023

Manufacturing active and economical catalysts and using them in water treatment is one of the most important challenges facing researchers. Spent batteries signify a source of harmful materials when discarded without suitable treatment. In this work, a black paste as one of the main components of spent battery doped with different ratios of TiO2 nanocomposites (0, 1, 3, 7, and 10 %) were manufactured using the sol–gel method. The characterization of the paste@TiO2 nanocomposites has been investigated by SEM, XRD, DRS, FTIR, and BET analysis. The results show formation of anatase phase of TiO2 in all doped samples. While the XRD of black paste indicates the presence of Mn3O4 as a main phase. Photocatalytic properties of black paste@TiO2 nanocomposites have been investigated using Congo red dye. The results showed that the presence of TiO2 in the paste could increase the specific surface area and the composites’ photocatalytic efficiency. A higher percentage of TiO2 (10 %) added to the black paste resulted in higher black paste@TiO2 nanocomposite catalytic activity. The experimental photodegradation data were found to be consistent with the Lagergren kinetics model. The recyclability of the photocatalysts was examined for reuse in the industrial sector. Signifying that the black paste dopped with 10 % of TiO2 (PTO4) photocatalyst in this study had high reusability.
Tyrosine Kinase Inhibitor Antitumor Therapy and Atrial Fibrillation: Potential Off-Target Effects on Mitochondrial Function and Cardiac Substrate Utilization
Authors: Li Yukun , Peng Xiaodong , Lin Rong , Wang Xuesi , Liu Xinmeng , Meng Fanchao , Ruan Yanfei , Bai Rong , Tang Ribo , Liu Nian
Published: November 2023

Tyrosine kinase inhibitors (TKIs) are a novel category of antitumor agents with remarkable efficacy in extending patient survival. However, clinical use of TKIs has been hindered by the major adverse effect of atrial fibrillation (AF). Recent studies have revealed that TKIs induce metabolic alterations and remodeling in cardiomyocytes, thus perturbing energy metabolism. Specifically, mitochondrial dysfunction and shifts in cardiac substrate utilization have been implicated in the mechanisms underlying TKI-induced AF. In light of these findings, this article reviews the energy metabolism-associated pathways involved in TKI-induced AF, identifies precise therapeutic targets for managing this condition, and discusses evidence that may contribute to the development of novel TKIs without cardiac adverse effects.
In VivoOptical Interrogation of Neuronal Responses to Genetic, Cell Type-Specific Silencing
Authors: Terzi Firat , Knabbe Johannes , Cambridge Sidney B.
Published: November 2023

We established a low background, Cre-dependent version of the inducible Tet-On system for fast, cell type-specific transgene expressionin vivo. Coexpression of a constitutive, Cre-dependent fluorescent marker selectively allowed single-cell analyses before and after inducible, Tet-dependent transgene expression. Here, we used this method for precise, acute manipulation of neuronal activity in the living brain. The goal was to study neuronal network homeostasis at cellular resolution. Single induction of the potassium channel Kir2.1 produced cell type-specific silencing within hours that lasted for at least 3 d. Longitudinalin vivoimaging of spontaneous calcium transients and neuronal morphology demonstrated that prolonged silencing did not alter spine densities or synaptic input strength. Furthermore, selective induction of Kir2.1 in parvalbumin interneurons increased the activity of surrounding neurons in a distance-dependent manner. This high-resolution, inducible interference and interval imaging of individual cells (high I5, HighFive) method thus allows visualizing temporally precise, genetic perturbations of defined cells.

SIGNIFICANCE STATEMENTGene function is studied by KO or overexpression of a specific gene followed by analyses of phenotypic changes. However, being able to predict and analyze exactly those cells in which genetic manipulation will occur is not possible. We combined two prominent transgene overexpression methods to fluorescently highlight the targeted cells appropriately before cell type-specific transgene induction. By inducing a potassium channel that decreases neuronal firing, we investigated how neuronal networks in the living mouse brain possibly compensate swift changes in cellular activities. Unlikein vitro, known compensatory homeostatic mechanisms, such as changes in synapses, were not observedin vivo. Overall, we demonstrated with our method rapid genetic manipulation and analysis of neuronal activities as well as precision transgene expression.
Health System for Exercise Rehabilitation Detection Retina Images and IoT Blockchain
Authors: Sriman B , R Seetha , M Mustafa Nawaz S , Velmurugan V , Kumar N R Sathis , Silviya S H Annie
Published: November 2023

Smart Healthcare which is based on deep learning is becoming increasingly popular because of its practical applications and has grown popular after its incorporation with IoT. Degenerative eye disease is the main factor of blindness in people of working age. Asian nations with large populations, like India and China, are on the edge of a diabetes epidemic. In terms of medical screening and diagnosis, a large number of diabetes patients posed a huge problem for skilled clinicians. The idea is to employ deep learning algorithms to detect blind spots in the eye and estimate the severity of the stage. We present an optimum approach for detecting blindness in retinal images based on recently released pre-trained EfficientNet models, as well as a comparative assessment of many innovative neural network models, in this study. On a benchmark dataset of retina images obtained by diagnostic imaging at various imaging phases, our EfficientNet-B5-based model assessment performs better than CNN and ResNet50 models.
Effect of Foot Reflexology on Clinical Outcomes of Neonates with Hyperbilirubinemia
Authors: Mahdy Noura M. , Mahdy Noura M. , Kreem Hekmat E. Abed El , Mohamed Nahed T. , Aziz Safwat M. Abdel
Published: November 2023

Background and objectives: Neonatal hyperbilirubinemia is the most common reason for admission to Neonatal Intensive Care Unit (NICU) that can progress to critical levels. So, foot reflexology is one of the most widely used treatments and it is effective not only in the treatment of illnesses but also in maintaining health. Objectives: This study aimed to determine the effect of foot reflexology on the clinical outcomes of neonates with hyperbilirubinemia.Methods: A quasi-experimental research design was utilized in this study. The study subjects were 60 neonates with hyperbilirubinemia, recruited from NICU in Assiut University Children's Hospital. They were selected randomly and divided into two groups: the study group received foot reflexology interventions and the control group received routine care. Two tools were used to collect the necessary data, which included a personal structure questionnaire and neonataloutcomes assessment sheet.Results: On the fifth day, the mean of total serum bilirubin over the study group was 7.89±1.12 mg/dl, and over the control group was 10.55±0.55 mg/dl. According to the mean of the duration of phototherapy and hospital stay, the study group was 3.86±0.86- 6.80±0.88 respectively, but over the control group was 5.33±0.75- 10.40±1.22 respectively.Conclusions: A statistically significant positive correlation between applying foot reflexology interventions and improving clinical outcomes of neonates with hyperbilirubinemia. We recommended that in-service training and education programs for neonatal nurses should be conducted on a regular basis to teach them non-pharmacological strategies such as foot reflexology techniques.
Connecting Top Management Team (TMT) Characteristics to Earning Management: Sample Companies in Saudi Arabia
Authors: Amamou Meriam , Kasraoui Naziha
Published: November 2023

This study investigates whether specific characteristics of a firm's top management team (TMT) affect the company's earnings management (EM) in Saudi Arabia. The data was collected from 163 companies listed in Saudi Arabia from 2017 to 2021. The TMT characteristics were measured using two different criteria: the academic qualifications and the management expertise of the team. Two models were used to analyze the data: the modified Jones model (1995) was used to measure accrual management, and the Kothari model (2006) was used to estimate accrual discretionary. The research findings revealed that TMT characteristics do not significantly impact EM in Saudi Arabia. According to the Kothari model approach (2006), both the academic qualifications and the management expertise did not influence EM. However, when we followed the Jones model approach (1995), the results showed that management expertise significantly and positively impacts EM. On the other hand, the academic qualifications do not seem to significantly impact EM.
The Correspondence of the Equal Two-Component Phraseologies in Terms of Construction
Authors: Gulara Aynazarova , Sharigul Allaniyazova
Published: November 2023

In the article, the grammatical compatibility of two-component phraseology that stands out as a different structure in the Karakalpak language is discussed with examples. Various grammatical formants connecting the lexemes in the composition of such phraseology are used in the form of repetitions or referring to the similarity. Correspondences in the creation of phraseology create strong harmony, and rhythm.
The Psychological Characteristics and Job Satisfaction in Relation to The Happy Workplace of Electrical Industrial Factory Personnel in Pathumthani Province.
Authors: Chantabul Phongthawach
Published: November 2023

The objectives of this research aimed to study 1) the level of significance of psychological characteristics, job satisfaction and happy workplace of electrical industrial factory personnel in Pathumthani Province. 2) To study the relationship between psychological characteristics and happy workplace of electrical industrial factory personnel in Pathumthani Province. 3) To study the relationship between psychological characteristics and job satisfaction of electrical industrial factory personnel in Pathumthani Province. 4) To study the relationship between job satisfaction and happy workplace of electrical industrial factory personnel in Pathumthani Province. The population is the personnel from a total of 191 electrical industrial factories in Pathumthani Province. Using Taro Yamane’s formula, 35 electrical industrial factories were selected to be calculated with unknown population sample size. A sample of 385 personnel with 11 production personnel were purposive sampled from each factory. Statistical tool was questionnaire, and statistics used for analysis were frequency, percentage, mean and Pearson's correlation coefficient. The research had found that: 1) The overall level of significance of psychological characteristics, job satisfaction and happy workplace was found that in general the level of importance was high at average of 3.67, when considered individually, it was found that the highest aspect was happy workplace at average of 3.74, followed by job satisfaction at average of 3.71, and psychological characteristics at average of 3.57. 2) The relationship between psychological characteristics and happy workplace of electrical industrial factory personnel in Pathumtani Province had a high positive correlation (r = .972, Sig <.05). 3) The relationship between psychological characteristics and job satisfaction among electrical plant personnel in Pathumtani Province and electrical industrial factory personnel in Pathumtani Province had a high positive correlation (r = .771, Sig <.05). 4) The relationship between job satisfaction and happy workplace among electrical plant personnel in Pathumthani Province and electrical industrial factory personnel in Pathumtani Province had a high positive correlation (r = .843, Sig <.05).
The Extent to Which Lecturers at Jordanian Universities Utilize Infographic Guidelines for Curriculum Design
Authors: Fraihat Nesreen Bassam , Alenezi Raheeq Soudan , Alenezi Areej Soudan , Alkhalaileh Mohannad S.
Published: November 2023

This research aims to discover the degree to which faculty members use educational infographic design standards in computerized courses. So, the study adopted the descriptive analytical method; a questionnaire was used to collect data and then distributed to a sample of 149 faculty members in Jordanian universities. Accordingly, the study results showed that the degree of use of educational infographic design standards by faculty members in Jordanian universities in computerized curricula is moderately high. In addition, there indicated no statistically significant differences in the estimates of faculty members in Jordanian universities due to gender and the certificate source.
Володимир Вернадський і сучасна мінералогія
Authors: Павлишин Володимир Іванович , Пономаренко Олександр Миколайович , Чернієнко Наталія Миколаївна
Published: November 2023

У статті в історичному контексті висвітлено роль В.І. Вернадського як реформатора мінералогії, який першим у світовій науці показав значущість природної історії мінералів і вивчення хімічних процесів, що зумовлюють зародження, ріст та змінення мінералів. Оновлена Вернадським мінералогія набула в Україні потужного розвитку. Стисло розглянуто структуру, здобутки, історично значуще каміння та подальші перспективи мінералогії в Україні. Обґрунтовано доцільність пріоритетного розвитку прикладних робіт, спрямованих на створення нових гірничорудних галузей.
Сивий орій
Authors: Коваленко Олексій Григорович
Published: November 2023

Цього року виповнилося 95 років від дня заснування Інституту мікробіології і вірусології ім. Д.К. Заболотного НАН України. За цей час установа неодноразово зазнавала реформувань, злетів, випробувань. Інститут славний своїми розробками і за деякими важливими напрямами посідає провідне місце не лише в українській, а й у світовій науці. Свого часу Інститут координував у колишньому СРСР усі дослідження з фітонцидів та вірусних хвороб рослин. Своїми досягненнями та здобутками у вирішенні нагальних наукових проблем установа зобов’язана потужному науковому колективу, одним із яскравих лідерів якого був Семен Микитович Московець. Ця стаття — щупта вдячності, спомин і водночас панегірик на честь цього видатного вченого, організатора науки, вчителя, славного сина українського народу від одного з його учнів і послідовників.
Innovations in Cancer Treatment of Children
Authors: Helms Lauren , Guimera Allison E. , Janeway Katherine A. , Bailey Kelly M.
Published: November 2023

Pediatric cancer outcomes have significantly improved, and yet this success is not spread equally across cancer types or patients. Disparities data in pediatric oncology highlight needed improvements in access to care, including clinical trials and advanced testing for all patients. For cancers such as brain tumors and sarcomas, continued advancement in understanding the biology of tumor heterogeneity is an essential step toward finding new therapeutic combinations to improve outcomes. Pediatric cancer survivors need access to emerging technologies aimed at reducing or better managing toxicities from therapy. With advances in treatment and survival, pediatric oncology patients continue to need longitudinal, multidisciplinary subspecialty care. Refining the communication between pediatric oncologists, primary pediatricians, survivorship clinics, and adult primary care is key in ensuring the best lifelong care of pediatric cancer survivors. In this State-of-The-Art review, we discuss 5 major domains in pediatric oncology: reducing toxicity, cancer biology, novel therapies, detection and monitoring, and access to care, to highlight recent advances and areas for continued improvement.
OUVERTURE: crônicas do Instituto Rio Branco
Authors: BRIGIDI DE MELLO EDUARDO
Published: November 2023

Relevante sob os pontos de vista social, cultural e pedagógico, “Ouverture” traz as impressões de um diplomata recém-ingressado no Instituto Rio Branco, academia diplomática brasileira. A iniciação no Ministério das Relações Exteriores é relatada em chave literária, sob tom que mescla prosa e poesia, com riqueza de detalhes sobre experiências vividas pelo autor nos primeiros quinze anos de carreira. O texto explora, sob ponto de vista autoral, variados aspectos dos primeiros passos no Itamaraty, transitando da dimensão pessoal e familiar até questões de política internacional e de política externa do Brasil. É obra de interesse tanto para o público em geral, especialmente aspirantes à carreira diplomática, como referência para o público acadêmico especializado, notadamente alunos e pesquisadores das áreas de Relações Internacionais e áreas afins.
From “actually existing socialism” to actually existing post-socialism: János Kornai and the importance of language reform in political economy
Authors: Madlovics Bálint , Magyar Bálint
Published: November 2023

This paper discusses the contributions of János Kornai to the “language reform” of socialism and post-socialism, meaning the creation of new conceptual frameworks to replace the mainstream interpretation of the system with a more realistic, critical description. We show that, in the three waves of language reform under the Kádár regime – economics, sociology, and law – Kornai was a trailblazer by introducing concepts like “soft budget constraint,” “plan bargaining,” and “shortage,” which became key concepts for reform economists and dissident intellectuals in Eastern Europe. We discuss Kornai's work on post-socialism as well, particularly his paper “The System Paradigm Revisited,” and point out its merits and shortcomings in the description of the regimes of the region. Presenting our offer for a new language reform, based on Kornai, we underline the importance of proper words for understanding “actually existing post-socialism,” and the task of political economists to revise the current mainstream and analyse the phenomena of post-communist “relational economies.”
The place of dichotomous structures in the thought system of János Kornai
Authors: Mihályi Péter
Published: November 2023

The most significant concept of János Kornai's oeuvre is the shortage economy theory as it was presented in Anti-equilibrium more than fifty years ago. According to this, modern economies are never in equilibrium. On the markets of goods and services, the aggregate demand is either significantly higher or significantly lower than the aggregate supply. This dichotomous model is discussed in the first part of the paper.

After the collapse of the communist system in 1989/90, shortages disappeared everywhere unexpectedly quickly. But it was also an unexpected development that the institutions of liberal democracy have not developed in several countries and/or collapsed after a short period. Regarding Hungary, Kornai issued an alarm signal at the turn of 2010/2011. He was the first who said that the Orbán regime had turned the country into an autocracy in barely a year. The second part of the paper examines whether Kornai's assertion, shared by many transition-economy specialist, that there are only two political systems (democracies and autocracies) is adequate for the entire range of post-socialist countries. The author's answer to this question is negative.
The connection between growth imperative of monetary production economies, the realization problem and Kornai's surplus economy
Authors: Gilányi Zsolt
Published: November 2023

Kornai challenged not only the dominant economic views of the socialist system, but also those of market economies. The former brought him fame, and the latter remained, so to speak, his scientific testament. He studied the systemic properties of different economic systems through the analytical grid of the sign of aggregate excess supply, which defined three categories: shortage economies, equilibrium economies and surplus economies. In this paper, we show that business plans postulated with the aim of realizing strictly positive net retained profits in nominal terms exclude equilibrium economies; these business plans imply a surplus economy. This definition of the business plan makes it possible to combine seemingly disparate results from different parts of the economic literature. An economy in which business plans are the rule and no economic agent can run a permanent negative budget is a surplus economy, which manifests itself in the phenomena of both growth imperative and realization problem. In short, all these phenomena are the manifestations of the same essence: the working of the business plans.
“Celestial” snapshots: Moral economic revisitations of János Kornai's the socialist system
Authors: Hajnal Zsófia
Published: November 2023

Significant parts of the work of the great economist and economic visionary János Kornai function as a magnifying glass in economic theory, philosophy and history. Kornai examined economic systems and system-mixes with substantial details, for then being able to focus his audiences' attention on the most relevant and critical aspects of them. One of Kornai's masterpieces, The Socialist System – a book which recently passed its 30-year publishing anniversary – is such a political economy lens on communism. I am attempting a concise conversion of this magnifying glass, to apply a Galileian metaphor, into an economic telescope. In other words, I am adding another economic lens – that of moral economics – to the Kornaian viewpoints. In a short analysis going through various dimensions of The Socialist System, I am coupling Kornai's thoughts with moral economic ideas, both from the classical and the contemporary moral economy streams. The goal with this exercise of respectfully refreshing a toolkit and style of economic analysis is to then gaze into, and partially describe a potential multitude, or spectra of economic systems, which may manifest in econodiversity.
Studies on scientific literacy in primary education: A bibliometric and content analyses
Authors: Kutlu-Abu Neşe , Bozgün Kayhan , Uluçinar-Sağir Şafak
Published: November 2023

This study aims to ascertain the research trends of articles on scientific literacy in primary schools. In the study, both bibliometric and content analysis techniques were employed. In the Web of Science database, 145 studies conducted between 1993 and 2021 and 60 studies conducted between 2002 and 2021 were included in the content analysis for bibliometric analysis. According to the findings, there is a rising interest in scientific literacy in primary schools. Bybee, R., and McCrae, B., were the most cited authors in this study. The United States was the most frequently cited country, and the Australian Council for Educational Research was the most frequently cited institution. Few mixed studies have been conducted on the topic of scientific literacy, as qualitative studies have dominated the field. As sample groups, primary school students and college graduates were favored. The study concluded that scientific literacy in primary school is mostly promoted by organizations, journals or authors in developed countries. The results of the study were discussed in light of the relevant literature, and suggestions for further studies were offered.
Dihydrokaempferol attenuates LPS-induced inflammation and apoptosis in WI-38 cells
Authors: Wang Qiao , Zhang Liwen , Pang Ping
Published: November 2023

Background: Globally, pneumonia has been associated as a primary cause of mortality in children aged less than 5 years. Dihydrokaempferol (DHK) has been proposed for being correlated with the process of various diseases. Nevertheless, whether DHK has a role in the progression of infantile pneumonia remains unclear. This study aimed at exploring whether DHK was involved in the progression of infantile pneumonia.
Methods: Human fibroblast cells WI-38 were treated with lipopolysaccharide (LPS). The viability of WI-38 cells was measured via Cell counting kit-8. Reverse transcription-quantitative polymerase chain reaction was used to evaluate the levels of interleukin (IL)-1β, IL-6, and tumor necrosis factor-α (TNF-α). Western blot analysis revealed the protein levels of IL-1β, IL-6, TNF-α, Bax, and cleaved-caspase 3. Flow cytometry was applied for exploring the apoptosis of WI-38 cells. The concentrations of IL-1β, IL-6, and TNF-α were assessed via enzyme-linked-immunosorbent serologic assay.
Results: DHK modulated the viability of WI-38 cells in infantile pneumonia. Furthermore, we identified that DHK treatment inversely changed LPS induction-mediated elevation on the levels of inflammation biomarkers. Besides, DHK counteracted LPS-induced production of reactive oxygen species (ROS) in WI-38 cells. DHK also decreased LPS-induced elevation of WI-38 cells apoptosis and mediated the levels of apoptosis-associated indexes. Moreover, modulating sirtuin-1 (SIRT1) protein level was lowered by the induction of LPS, and was reversed by DHK treatment. In addition, DHK counteracted LPS induction-mediated elevation of p-p65 and phosphorylated inhibitor of nuclear factor kappa-B kinase subunit alpha (p-IκBα) protein levels.
Conclusion: DHK alleviated LPS-induced WI-38 cells inflammation injury in infantile pneumonia through SIRT1/NF-κB pathway. The results shed light on the implications of DHK on the prevention and treatment of infantile pneumonia.
La musica per la liturgia nel nostro tempo: quale linguaggio?
Authors: Panzetti Pietro
Published: November 2023

L’articolo descrive il progetto, sviluppato  nella Cattedrale di Lodi, che ha portato alla composizione di canti d’introito per le domeniche e le feste principali dell’anno liturgico. Partendo dai principi di nobiltà e semplicità, i brani composti, sfruttando il tesoro della tradizione musicale liturgica, intendono rispondere alle esigenze liturgiche attuali.
Resounding Through the Ages: The Seven Last Words of Christ
Authors: Benda Jacob
Published: November 2023

The life, death, and resurrection of Jesus Christ has served as the source for innumerable musical creations spanning the centuries, including a colorful array of compositions inspired by The Seven Last Words of Christ. This musico-theological analysis is an attempt to describe how Part I of Pamela Decker’s epic work for solo organ, The Seven Last Words and Triumph of Christ, artfully communicates the power, depth, and beauty of Christ’s timeless words by way of pitch, rhythm, texture, registration, and use of pre-existing melody.
Caminos de reencuentro
Authors: Espinoza Pabón Myriam
Published: November 2023

En este artículo se realiza una serie de reflexiones sobre los principales aportes del capítulo siete, titulado Caminos de reencuentro, de la Carta Encíclica Fratelli Tutti del Papa Francisco publicada en el mes de octubre de 2020; es una invitación al cuidado de sí mismo y del prójimo, fundamentada en la solidaridad, fraternidad y acogida. Específicamente se abordan los temas de la paz, el perdón, la guerra y la pena de muerte.
Historicidad de los conceptos de infancia y educación en Colombia
Authors: Portilla Benavides Milton Mauricio
Published: November 2023

El presente escrito invita al lector a conocer aspectos generales sobre la evolución del concepto de infancia y cómo esta dinámica ha fortalecido el proceso de la formación y educación de los niños y niñas en Colombia. Inicialmente, se plantea un recorrido histórico para descubrir los aspectos y las visiones de los adultos frente a los niños; seguidamente, el texto va mostrando cómo los gobiernos y las políticas, en especial en Colombia, han avanzado de tal manera que se convierten en recursos importantes, en dispositivos pedagógicos potentes que permiten pensar la educación de la Primera Infancia, desde un escenario que reconoce el valor humano, cognitivo y social de los niños y niñas como sujetos de derechos.
El entendimiento humano y la fascinación por las tecnologías
Authors: López Moreno José Bernardo
Published: November 2023

Siempre ha sido una fascinación para la inteligencia conocer y entender la realidad en donde se habita, situación que implica tener una visión amplia que permita interpretarla para darle contenido y sentido a todo cuanto en ella se hace. En esa perspectiva, el conocimiento se convierte en un factor transformador de la realidad que mediante el uso de las nuevas tecnologías apunta a un desarrollo cada vez más amplio y asombroso, como lo está siendo hoy la inteligencia artificial.
Pensamiento económico y social de Osvaldo Sunkel para América Latina
Authors: Casanova Guerrero Ana Lucía , Paz Yaqueno Armando
Published: November 2023

El pensamiento económico de Osvaldo Sunkel, es uno de los sustentos teóricos del modelo de desarrollo Endógeno, o Hacia Dentro, tenido en cuenta en la construcción del modelo de desarrollo neoestructural que se está ejecutando por parte de algunos gobiernos de países de América Latina como Venezuela, Ecuador y Bolivia.

Este artículo presenta un análisis crítico al sistema  capitalista, más concretamente al modelo de desarrollo neoliberal o de capitalismo salvaje que se viene aplicando en Colombia desde 1989, después de treinta años de no haberse logrado solucionar los graves problemas económicos, sociales y ambientales, antes por el contrario, se han agravado; el proceso de concentración de la riqueza se ha acelerado junto con la inequitativa distribución de la misma, donde los países de la Organización para la Cooperación y el Desarrollo Económico (OCDE4) son los más favorecidos, mientras la pobreza y la miseria han crecido aceleradamente en los últimos años, especialmente en los países del tercer mundo.

Por otra parte, el sistema capitalista mundial se enfrenta a una gran crisis, que cada vez se torna en una gran depresión parecida a la de los años treinta, lo que amerita la aplicación de otra propuesta de desarrollo económico y social alternativa al pensamiento ortodoxo, como la propuesta expuesta por Osvaldo Sunkel
Os leilões de cruzeiros e a taxa de deságio dos cruzados novos
Authors: GIAMBIAGI FÁBIO
Published: November 2023

RESUMO Este artigo é uma tentativa de calcular qual deve ser o desconto de NCZ$ se o Banco Central do Brasil fizer leilões para convertê-los em Cr$. Usando algumas fórmulas simples da matemática financeira, é mostrado que o desconto é uma função direta da taxa de juros esperada do mercado e uma inversão de prazo até a conversão de NCZ $ em Cr$. Com base nisso, é feita uma matriz de resultados, que pode ser útil para isolar o desconto devido exclusivamente à desconfiança de todo o desconto. A conclusão mais notável é que o desconto pode ser alto mesmo em um contexto de total confiança, apenas porque a taxa de juros esperada do mercado também é alta.
A controvérsia da desconcentração geográfica da indústria na década de 70
Authors: FERREIRA CARLOS MAURÍCIO DE CARVALHO
Published: November 2023

RESUMO Este artigo examina os efeitos da segmentação dos mercados de trabalho e bens sobre a dispersão de preços e salários relativos na economia brasileira. O argumento teórico baseia-se no comportamento das empresas nos setores oligopolista e competitivo da economia, por um lado, e no comportamento do trabalho organizado e não organizado, por outro. Sugerimos que as negociações entre firmas oligopolistas e trabalho organizado possam ser vistas como um jogo de soma positiva; enquanto um jogo de soma zero caracteriza a distribuição de renda na economia como um todo. Portanto, concluímos que houve uma redistribuição de renda em favor dos lucros e salários dos agentes que atuam nos setores oligopolistas, em detrimento dos outros agentes da economia.
Dolarização crônica: Argentina e Brasil
Authors: BRESSER-PEREIRA LUIZ CARLOS , FERRER ALDO
Published: November 2023

RESUMO A dolarização é geralmente um fenômeno monetário agudo. Acompanha processos inflacionários de curta duração. Na América Latina, é comum ouvir-se uma ameaça de dolarização, mas a dolarização efetiva ocorre apenas com a hiperinflação. Uma exceção é a Argentina, onde há um fenômeno historicamente novo: uma dolarização crônica e duradoura. Se a inflação crônica (inercial) é particularmente difícil de controlar, a dolarização crônica é ainda mais difícil.
Performance indicators of Primary Care of the Previne Brasil Program
Authors: Schönholzer Tatiele Estefâni , Zacharias Fabiana Costa Machado , Amaral Gabriela Gonçalves , Fabriz Luciana Aparecida , Silva Brener Santos , Pinto Ione Carvalho
Published: November 2023

Objective: to analyze the scope of the performance indicators of the Previne Brasil Program of Primary Health Care. Method: an observational, descriptive study with a quantitative approach was carried out using secondary data, referring to the years 2020 and 2021, in the five Brazilian regions (North, Northeast, South, Southeast and Midwest), available in the Primary Health Care Information System. Descriptive statistics, relative frequencies and measures of central tendency and semiparametric modeling were used considering a 5% confidence interval. Results: there was evidence of evolution in the rates of performance indicators in most Brazilian regions in 2021, compared to 2020, however, the North and Midwest regions had incipient or negative rates, compared to the Southeast region. Despite the evolution in the rates of the indicators, few States managed to reach the goals established by the Ministry of Health for the strategic actions of prenatal care and women’s health; and no state achieved the goal in strategic action on chronic diseases. Conclusion: it is considered important to monitor the evolution of current indicators, envisioning their qualification so that they can evaluate primary health care and assistance, as well as guarantee the achievement of goals by ensuring funding for primary care actions.
Characterization and distribution of Teredinidae assemblage in an estuary in Ceará, Brazil's Northeast
Authors: Carmo-Santos E. , Santos M. R. , Rocha-Barreira C. A. , Maia R. C.
Published: November 2023

Abstract Teredinids are bivalves mollusks considered the most abundant of invertebrates group of marine wood borers performing an important role in the mangrove environment. This study aimed to characterize the Teredinidae species from the Acaraú River estuary in Ceará and analyse the relationship between the mangrove plant structure and the distribution of Teredinidae, according to gradients estuaries: vertical (flooding) and horizontal (salinity). The collection of mangrove logs with Teredinidae happened in three places within the estuary (inner, median, and upper); in each area, three transects were traced in which three plots were lined off, and a total of 40 logs were collected. Teredinidae species were found and identified: Nausitora fusticula; Neoteredo reynei; Teredo turnerae; Teredo cf. bartschi; Bankia bipennata; Bankia gouldi; Lirodus massa and Lyrodus cf. bipartitus. The Lyrodus cf. bipartitus, Bankia gouldi, and Teredo cf. bartschi species were registered for the first time in Ceará. The distribution and species richness of Teredinidae were directly related to the vertical gradient (flooding) and heterogeneity of the mangrove forest habitat. The data presented here are essential for comprehending the mechanisms responsible for the distribution patterns of the Teredinidae species in the mangrove, contributing to biodiversity conservation in Ceará coastal zones.
Diversity of nitrogen-fixing and phosphorus-solubilizing bacteria associated with the rhizosphere of Andean maize in Ecuador
Authors: Sangoquiza-Caiza C. A. , Pincay-Verdezoto A. K. , Park C. H. , Zambrano-Mendoza J. L.
Published: November 2023

Abstract A great diversity of microorganisms in the soil plays an important role in the sustainability of agricultural production systems. Among these microorganisms are bacteria that have the ability to fix atmospheric nitrogen or mineralize phosphorus, thus making it easily assimilable for plants. Maize is the main crop in the highlands of Ecuador (above 2000 meters) and it is predominantly traditional, using native seeds and very little or no agrochemicals. The National Institute of Agricultural Research (INIAP) has a collection of bacteria collected from the rhizosphere of maize in the highlands of Ecuador that has not been taxonomically identified. This research aimed to carry out a biochemical and genetic characterization to establish the identity of the collected nitrogen-fixing and phosphorus-solubilizing bacteria and to understand better the diversity of microorganisms present in the root biome of Andean maize. The hypothesis consisted of determining if there is a difference in the bacteria associated with the rhizosphere of maize in the Andean region of Ecuador compared with other regions. The bacteria underwent classical biochemical characterization based on catalase, oxidase, urease, sulfates, indole, sulfate-indole motility (SIM), and lactose, among others, and genetic identification by 16S rDNA ribosomal gene sequencing, PCR, and SANGER sequencing. A great diversity of microorganisms associated with the rhizosphere of the crop was found, including the genera Agrobacterium, Bacillus, Stenotrophomonas, Acinetobacter, Brevundimonas, Pseudomonas, and Pseudoxanthomonas. INIAP conserves these bacteria in a bank of microorganisms associated with crops of economic importance. They are useful for the development of biofertilizers that could contribute to a more sustainable agriculture in the region.
Sexual dysfunction in the climacteric period and associated factors
Authors: Gonçalves Jaqueline Teixeira Teles , Gonçalves Camila Teles , Vieira Kássia Héllen , Santana Renata Ferreira , Reis Vivianne Margareth Chaves Pereira , Silveira Marise Fagundes
Published: November 2023

Abstract Objectives: to evaluate associated factors with sexual dysfunction among middle-aged women. Methods: cross-sectional and analytical study was carried out with climacteric women attended at a Family Health Strategy Unit in the city of Montes Claros, MG. Brazil. The eligible women answered a question form containing sociodemographic, behavioral, anthropometric, gynecological factors and sexuality. The Body Mass Index and waist circumference were used to assess nutritional status and metabolic risk. To evaluate quality of life and sexual performance the Menopause Rating Scale and the Sexual Quotient - Female Version were used, respectively. Bivariate analysis and hierarchical multiple regression were used to identify associated factors with sexual dysfunction in the climacteric period. Results: among 195 women, 29.6% had sexual dysfunction. The prevalence of unsatisfactory sexual performance was higher among women who reported moderate to severe climacteric symptoms (OR=2.47) and lower schooling level was also associated (OR=1.95). However, age at menarche below 12 years (OR=0.43) and non-white (OR=0.36) seem to have a protective effect for good sexual performance. Conclusion: the prevalence of sexual dysfunction was high and the level of schooling and climacteric symptomatology were associated factors with this outcome.
Intrauterine diagnosis and follow-up of a child with Goldenhar Syndrome: case report
Authors: Lima Victor Fernando da Silva , Pinto Bruna Assis Tenório , Nelson Claudia Bem Leite , Campos Eduarda Medeiros , Gonsioroski Lucas Pacheco , Souza Mariana Rodrigues dos Santos , Siqueira Rayza Cecília Chaves de , Vilarim José Nivaldo de Araújo
Published: November 2023

Abstract Introduction: goldenhar syndrome is a rare congenital syndrome that affects the craniofacial morphogenesis. It is a complex syndrome, with heterogeneous presentation which the diagnosis can still be performed in the intrauterine through morphological ultrasound. Description: a case report of a 4-year-old male patient diagnosed with Goldenhar syndrome, along with its clinical presentation, diagnostic investigation and follow-up. Discussion: the follow-up on these patients remains a challenge, since it can affect different systems and with different presentations. The earlier the diagnosis is performed, the greater the patient’s chances of having a favorable prognosis with multidisciplinary stimulation. The objective of this article is to contribute to the medical literature, in order to assist in the diagnosis and management of future cases.