bluuebunny/crossref_metadata_2025 huggingface dataset:
CONFORMITY VERSUS INFORMALITY: ON RELATIONSHIP BETWEEN THE SOCIALISTS AND BUREAUCRATIC ELITE IN TURKEY
Authors: KAYNAR Mete Kaan
Published: April 2019

Might the history of socialism in Turkey be

read as the history of “ostracism” and “proscription”

of the socialists from the political

system? On the other hand, might the socialists in Turkey be considered as a (one of the) outsider(s) or political (one of

the) enemy/enemies? This article wants to answer these questions and focus on

the problem of how Turkish socialists affect the political system, while they

are in mainly the outside of the system. The main argument of this article is

that the socialists can be considered as an outsider/public enemy of Turkish

political system by the bureaucratic elite,

but social relations occurred in the non-political institutions of Turkish

society have given opportunities to the socialists for affecting the political

system. In other words, nonpolitical

social institutions and daily social relations occurred in these institutions

have been the only space for the socialists to be politically active and to

illegally and informally affect the inside (formal institutions) of the political system. This is also one of the main

reason for the endemic informality and/or

illegality tradition in the Turkish left. The main aim of this study is to

explore the relationship, interactions, and

dilemmas regarding conformity versus illegality in line with the contradictive

evolvement of relations between the socialists and bureaucratic elite in the

Turkish political life.  
Western Blot Analysis of Leishmania infantum Antigens in Sera of Patients with Visceral Leishmaniasis
Authors: HEIDARI Soudabeh , GHARECHAHI Javad , MOHEBALI Mehdi , AKHOUNDI Behnaz , MIRSHAHVALADI Shahab , AZARIAN Bahareh , HAJJARAN Homa
Published: April 2019

Background: Visceral leishmaniasis (VL) is endemic in the northwest and south of Iran. Untreated cases of VL could cause death. The aim of the present study was to evaluate the diagnostic performance of western blotting to detect a specific immunodominant proteins pattern for Leishmania infantum infection using human sera infected with VL.
Methods: We studied a panel of 122 cryopreserved human serum samples from the leishmaniasis Research Laboratory, Tehran University of Medical Sciences, Tehran, Iran from 2010 to 2017.
Serum samples were collected from visceral (Group I, n: 43) and cutaneous leishmaniasis (CL) (Group II, n: 8) patients, healthy individuals from endemic (Group III, n: 13) and non-endemic (Group IV, n: 16) areas for VL, and patients with other infectious diseases (Group V, n: 42). Total antigens were prepared from the Iranian strain of L. infantum promastigote form.
Results: In western blotting method, 34 protein bands of 14 to 163 kDa were recognized using the sera of VL pa­tients. The polypeptide fractions with the highest frequency including 29, 51, and 62 kDa fractions were detected using 81.4%, 79%, and 81.4% of the sera, respectively. These bands were not detected using the sera of the negative control. Moreover, 19-23, 27, 31-35, 143-163, and 109 kDa fractions were detected specifically using the sera of the patients with VL.
Conclusion: This technique could be a primary step for further exploration of VL immunodominant antigens for cloning (or any technique) further investigations for future planning.
Inhibición de Colletotrichum gloeosporioides y Botrytis cinerea con extractos de Guazuma ulmifolia Lam
Authors: Ramírez-Salcedo Hilda Elisa , Barrientos-Ramírez Lucía , Vargas-Radillo J. Jesús , Rodríguez-Macías Ramón , Ruíz-López Mario Alberto , Virgen-Calleros Gil
Published: April 2019

Guazuma ulmifolia (Malvaceae) es un árbol utilizado en la medicina popular de múltiples países para tratar diversas enfermedades. Se evaluó el efecto inhibitorio de los extractos de la corteza y fruto de esta planta, obtenidos con solventes de polaridad creciente, contra Colletotrichum gloeosporioides y Botrytis cinerea. Se utilizó como criterio para elegir el solvente con mejor desempeño en la extracción, ensayos de cromatografía de capa fina (TLC) y el dato del rendimiento de extractos. Posteriormente, se analizaron los extractos por medio de tamizaje fitoquímico y se evaluó la actividad antifúngica con los métodos de TLC-Bioautografia e inhibición de crecimiento micelial, aplicando un diseño experimental aleatorizado. Los extractos del fruto fueron más efectivos que los extractos de corteza, y por su parte, C. gloeosporioides fue más resistente que B. cinerea. A 10 mg mL-1, los extractos de fruto inhibieron 85.5 ± 2.1% el crecimiento micelial de B. cinerea y en 45.8 ± 10.0% el de C. gloeosporioides, mientras que los extractos de corteza inhibieron en 58.0 ± 2.4% y 34.1 ± 2.9% el crecimiento de B. cinerea y C. gloeosporioides, respectivamente. Imágenes obtenidas microscopia óptica muestran que los extractos alteraron la morfología original tanto de los micelios como de las esporas.
Inductores de resistencia vegetal en el control de Candidatus Liberibacter asiaticus en árboles de limón (Citrus aurantifolia) mexicano
Authors: Trinidad-Cruz Jesús Rafael , Rincón-Enríquez Gabriel , Quiñones-Aguilar Evangelina Esmeralda , Arce-Leal Ángela Paulina , Leyva-López Norma Elena
Published: April 2019

El Huanglongbing representa un gran reto para su control, por lo que se requiere de alternativas efectivas a la aplicación de insecticidas al insecto vector. La inducción de resistencia sistémica es una alternativa para disminuir el progreso de la enfermedad en árboles infectados. El objetivo de este trabajo fue evaluar el efecto de inductores de resistencia sistémica sobre la concentración de ?Candidatus Liberibacter asiaticus? (CLas) en árboles de limón mexicano (Lm) en condiciones de invernadero. Los inductores de resistencia utilizados fueron ácido salicílico (T1), Azospirillum brasilense Cd (T2) y quitosano (T3), aplicados cada 20 días durante ocho meses. La cuantificación de CLas fue mediante qPCR. La concentración de CLas se determinó a los 1, 2, 5 y 8 meses pos-tratamiento. A los 8 meses pos-tratamiento, T1 y T3 no presentaron diferencias postratamiento en la reducción postratamiento de la concentración de CLas con respecto al control sin inductor (T4) (6.5×103 células bacterianas/100 ng de ADN), mientras que T2 disminuyó casi tres veces la concentración de CLas con respecto al control. La inoculación directa al suelo de A. brasilense Cd mostró un efecto significativo en la reducción de la concentración de CLas en los árboles de Lm en condiciones de invernadero.
Identificación de begomovirus en tomate y determinación de su transmisión por semilla en Atlacomulco, estado de México
Authors: Zuñiga-Romano Maria Del Carmen , Ochoa-Martínez Daniel Leobardo , Rojas-Martínez Reyna Isabel , Zamora-Macorra Erika Janet
Published: April 2019

En un invernadero de alta tecnología ubicado en Atlacomulco, Estado de México, se han observado incidencias del 60 al 90% de plantas con síntomas típicos de begomovirus. Los objetivos del presente estudio fueron identificar begomovirus presentes, conocer si se transmiten por semilla, determinar la especie de mosca blanca y si ésta es portadora de los virus. Hojas de plantas adultas con síntomas se analizaron con oligonucleótidos universales para begomovirus. Semillas de frutos de plantas positivas a begomovirus se sembraron en almácigos para obtener plántulas, éstas y parte de las semillas se analizaron por PCR para detectar begomovirus. Adultos de mosca blanca se analizaron con oligonucleótidos específicos del gen mitocondrial de la subunidad I del citocromo C oxidasa y con oligonucleótidos universales para begomovirus. Las secuencias de los productos obtenidos por PCR de plantas con síntomas tuvieron una similitud de 99% con el Tomato severe leaf curl virus (ToSLCV). No se detectaron begomovirus en semilla y plántula. Las secuencias obtenidas por PCR de mosca blanca en el invernadero tuvieron 99% de similitud con Bemisia tabaci y los individuos analizados fueron portadores del ToSLCV. Este es el primer reporte del ToSLCV asociado a tomate en invernadero en México.
Application of electromyography (EMG) in food texture evaluation of different Indian sweets
Authors: Sodhi Navdeep Singh , Singh Balkaran , Dhillon Bhavnita , Kaur Tanbeer
Published: April 2019

The present study was undertaken to correlate surface electromyography variables acquired during chewing of different Indian sweets with the instrumental texture parameters and their sensory attributes. Firstly, a comparison of acquired
absolute EMG variables with the relative EMG variables was conducted. The results revealed that the relative EMG mastication parameters can effectively distinguish different textured food products by eliminating the subject variance. Then, the two
different recordings of masticatory parameters in an EMG session for human subjects were correlated to investigate the reproducibility of chewing patterns. The correlation coefficients were found to be statistically significant (p less than 0.05)
indicating highly reproducible chewing behaviour within a session for human subjects. Finally, acquired surface EMG variables were clustered into six representative variables using dendrograms. The principal component analysis conducted for these
representative variables could explain 76% of cumulative proportion of variance. The scores of first principal component correlated significantly with instrumental and sensory hardness and sensory stickiness, while scores of second component
correlated with sensory stickiness.
Development of khoa based roll
Authors: Megha S. Shrimanwar , Chavan K. D.
Published: April 2019

The khoa roll samples were prepared by using of 0.5, 1.0, 1.5, 2.0, 2.5, 3.0 and 3.5 per cent cocoa powder and @ 22% sugar. On the basis of sensory evaluation, without addition of cocoa powder (T0), addition of 2.0% cocoa powder (T1), 2.5%
cocoa powder (T2) and 3.0% cocoa powder (T3) and 22% sugar level were selected for experimental trials. The experimental samples were evaluated for sensory,chemical and microbiological qualities. Experimental data was analyzed using standard method.
The sensory attributes i.e. colour and appearance, body and textureflavour and overall acceptability of the khoa roll samples significantly differed (P less than 0.05) due to addition of cocoa powder. The sensory scores for colour and appearance,
body and texture, flavour and overall acceptability of the product ranged from 7.58 to 8.06, 7.60 to 8.06, 7.60 to 8.20 and 7.60 to 8.20. There was significant differences (P less than 0.05) with respect to fat, protein, lactose, total solids,
titratable acidity and pH of khoa roll samples due to addition of cocoa powder. The mean fat, protein, lactose, total solids, titratable acidity and pH value ranged from 21.4 to 21.84 %, 17.31 to 18.74 %, 23.43 to 23.48 %, 67.27 to 69.63, 0.62 to
0.68 % LA and 6.18 to 6.21, respectively. The SPC and YMC count ranged from 5.4 x 102cfu/g (T0) to 8.2 x 102cfu/g (T3), 2.2 x 102cfu/g (T0) to 10.6 x 102cfu/g (T3), respectively. On the basis of results of sensory quality the better quality khoa roll
can be prepared by blend of 2.5 per cent cocoa powder and 22 % sugar in khoa.
Impact of different drying methods on sensory properties of osmotic dehydrated pineapple slices
Authors: Chaudhary Vipul , Kumar Vivak , . Sunil , Singh Balwant , Kumar Ratnesh , Kumar Vikrant
Published: April 2019

Drying is an essential process in the preservation of agricultural products. Various drying methods are employed to dry different agricultural products. Each method has its own advantages and limitations. Choosing the right drying system is
thus important in the process of drying agricultural products. Drying reduces the possibilities of the contamination by insects and microorganisms so that product is prevented. An experimental study was performed to determine the Sensory Evaluation
of pineapple slices subjected to drying in open sun drying, cabinet tray dryer at 50oC, 60oC and 70oC and hot air oven at 50oC, 60oC and 70oC with osmotic treatment indicated that T0 (Control), T1(50oBrix) and T2 (60oBrix). The result obtained showed
that a product osmo- treated 60obrix at 50oC tray dried shows the better texture, flavor, color, taste and overall acceptability.
Investigation of bile tolerance and deconjugation ability of various Lactobacillus Casei group strains
Authors: Kandola Suman
Published: April 2019

Lactobacillus casei group is commonly used as probiotics. Various factors affect their viability in gastrointestinal tract. Twenty two strains of Lactobacillus casei group were assessed for bile tolerance and deconjugation attribute. All
strains had shown moderate activity at 0% bile concentration. At 1% bile concentration CSCC 2607 has shown highest growth while remaining Lactobacillus strains have shown fair growth. At 1.5% bile concentration only seven Lactobacillus strains showed
growth and ASCC 1521 showed highest activity. All seven strains were able to deconjugate both sodium glycocholate and sodium taurocholate at varying levels. ASCC 1520 showed lowest deconjugation activity for sodium glycocholate. All seven strains
showed lower deconjugation of sodium taurocholate compared to sodium glycocholate. ASCC 290 was least capable of deconjugation of sodium taurocholate. When mixture of sodium glycocholate and sodium taurocholate having the similar molar ratio in human
bile, was taken, all seven strains showed consistent cholic acid secretion. ASCC 1521 also showed highest cholic acid liberation while ASCC 1520 showed lowest deconjugation ability. This study suggests the importance to identify all the useful
Lactobacillus strains which are able to tolerate and deconjugate, high bile concentration in order to study further for their therapeutic benefits.
ANALISIS PERMINTAAN KEDELAI DI INDONESIA
Authors: Pusposari Luthfiya Fathi
Published: April 2019

Indonesian population growth from year to year has increased, the population of Indonesia has incense for about 20 million people from the previous census data. Soybean is one of commodity most consumed by society census. Demand of soybean in this country 2,4 million tons per year, as much as 70% comes from imported soybean. Based on demand theory there are many factors that influence demand of goods, among others, the price of the goods themselves, the price of other goods, population, etc. Purpose of this research is to understand the elasticity of  soybean’s demand in East Java and what variable which have the highest elasticity. The result of this research shows that variable of soybean's price is in elastic towards demand of soybean while variable of corn's price, income per capita and population is elastic. Variable which has sensitivity or the highest elasticity is variable of population

Keyword: Demand, Elasticity, Soybean
STUDENTS’ ENGLISH SPEAKING SKILL AND ACTIVATION METHOD: THE CASE OF ONE SENIOR HIGH SCHOOL
Authors: Novita Tria
Published: April 2019

This study was aimed to find out whether or not: (1) there was a significant improvement on the eleventh grade students’ speaking skill who were taught by using activation method at MAN 3 Palembang before and after the treatment; and (2) there was a significant difference on the eleventh grade students’ speaking skill who were taught by using activation method and those who were not at MAN 3 Palembang. In this study, 60 eleventh grade students at MAN 3 Palembang were chosen as the sample. The students were grouped into two (i.e.: experimental group and control group). Experimental group consisted of 30 students, and control group consisted of 30 students. The experimental group was taught by using activation method, and the control group was taught by using teacher’s method. The data were collected by giving pretest and posttest to both groups. To analyze the data, paired sample t-test and independent sample t-test were used. The result of paired sample t-test showed that there was a significant improvement in students’ speaking skill for the experimental group. Independent sample t-test analysis showed that there was a significant difference in both of groups who were taught by using the activation method and those who were not (teacher’s method).
EBÜZZİYÂ TEVFÎK’İN SÜRÛRÎ-İ MÜVERRİH’İ
Authors: TIRAŞ Yusuf Can
Published: April 2019

Ebüzziyâ Tevfîk, Yeni Osmanlılar hareketi içerisinde
bulunan, yeni bir edebiyatın ortaya çıkarılması için çalışan önemli bir
gazetecidir. 1849’da İstanbul’da dünyaya gelen Ebüzziyâ Tevfîk, Terakkî
gazetesi ile gazetecilik hayatıa başlamıştır. Ardından Hakâiku’l-vekâyî,
Diyojen, Çıngıraklı Tatar ve Hayal gibi dergilerde de yazmaya devam etmiştir.
Ebüzziyâ Tevfîk, gazeteciliğin yanında dönemin siyasi koşullarıyla da ilgilenen
bir aydın şahsiyettir. Ebüzziyâ Tevfîk’in önemli bir yönü de dil ve edebiyat
konusunda yaptığı çalışmalardır. Tiyatro, sözlük, yıllık, tarih, tercüme,
derleme, antoloji ve biyografi türlerinde eserler yazan Ebüzziyâ Tevfik, çok
yönlü ve üretken bir yazar olarak göze çarpar. Bu biyografi eserlerinden birisi
de XVII. yüzyıl Divan Şairi olan Sürûrî’yi anlattığı, “Sürûrî-i Müverrih” adlı
eseridir. 54 sayfadan ibaret olan bu eser, tarafımızca günümüz alfabesine
aktarılmış ve hem Ebüzziyâ Tevfîk’in hem de Sürûrî’nin hayatı ve edebi
şahsiyetleri konusuna değinilmiştir.
ŞEYHÜLİSLAM YAHYA DİVANI’NDA UYKU KAVRAMININ KULLANIMI ÜZERİNE BİR İNCELEME
Authors: OKASSOVA Adiya
Published: April 2019

Uykuya antik
çağlardan beri büyük önem verilmiştir. Uyku, insan hayatının üçte birini
oluşturmaktadır. Bir insanın yaşaması için uyku vazgeçilmez bir ihtiyaçtır. Uyku, insan davranışlarını,
psikolojisini ve sağlığını etkileyen önemli bir süreçtir.

Türk edebiyatı ve halk
biliminde uyku kavramının çeşitli kullanımlarına rastlanmaktadır. Edebi
eserlerde uyku-uykusuzluk halinin en çok âşık–sevgili ilişkisinde ele alındığı
görülmektedir. Uykunun âşık için ayrı, sevgili için ayrı anlam ifade ettiği
belirlenmiştir. Bununla birlikte uyku çeşitli anlamlarıyla din ve tasavvuf
alanında kullanılmıştır. Beşerin dünya hayatında uykuda olduğunu gösteren
gaflet uykusu, ölüm karşılığında kullanılan ebedî uyku ve ecel uykusu gibi
uykunun çeşitli kullanımları vardır. Bu sebeple kültürümüzde uyku küçük ölüm
olarak nitelendirilmektedir. Şiirlerde ise naz uykusu, seher uykusu, tavşan
uykusu gibi uyku türleri kullanılmıştır. Dolayısıyla Divan edebiyatında uyku
kavramının kullanılması söz konusudur. 17. yüzyılın büyük şairlerinden biri
olan Şeyhülislam Yahya’nın Divan’ında uyku kavramının âşık-sevgili bağlamında
kullanıldığı görülmektedir. Bu çalışmada Şeyhülislam Yahya Divanı’nda uyku
kavramının kullanımı ve özellikleri üzerine bir inceleme yapılmaya
çalışılmıştır.
Şanlıurfa’da çalışan aile sağlığı elemanlarının iş doyum düzeyleri ve etkileyen faktörler
Authors: GÖKLER Mehmet Enes , DURMUŞ Hasan
Published: April 2019

Amaç: Çalışmada, Şanlıurfa ilinde hizmet veren aile
sağlığı elemanlarının demografik özellikleri, hizmet sundukları nüfusun
özellikleri, meslekleriyle ilgili düşünceleri, iş doyumları ve iş doyumu
üzerine etkili olabilecek değişkenlerin tespiti amaçlanmıştır. Yöntem:  Çalışma,
Şanlıurfa’da görev yapan aile sağlığı elemanları üzerinde yapılan kesitsel
tipte bir araştırmadır. Hesaplanan örneklem hacmine göre ilçe dağılımı ve
kır-kent hizmet sunumu durumu göz önünde bulundurularak rasgele seçilen 150
aile sağlığı elemanına ulaşılması hedeflendi. Hazırlanan anket formu, aile
sağlığı elemanlarının sosyo-demografik ve mesleki özelliklerini ve Minnesota iş
doyum ölçeğini içermekteydi.  Bulgular: Toplam 125 (%83.3) aile sağlığı elemanına
ulaşıldı. Çalışmaya katılan aile sağlığı elemanlarının %87.2’si kadın, %28.8’i
kırsalda hizmet vermekteydi. Çalışma grubunun genel, içsel ve dışsal iş doyum
puan ortalamaları sırasıyla 3.05±0.74, 2.79±0.79 ve 3.23±0.79 olarak bulundu.
Aile sağlığı elemanlarının %26.4’ünün iş doyumu yüksektir. Aile sağlığı
merkezinde kalıcı olarak çalışmayı düşünme [OR: 3.25 (1.18-8.96)] ve genel olarak işinden
memnun olma [OR: 4.46
(1.17-16.93)] iş doyumunun yüksek olmasında ilişkili faktörlerdir. Sonuç: Aile
sağlığı elemanlarının iş doyumu düzeyleri düşüktür. Aile sağlığı elemanları
birinci basamak sağlık hizmeti sunumun da önemli bir yere sahiptirler. İş
doyumlarını arttıracak düzenlemelerin yapılması hizmetin kalitesini
arttıracaktır.
Bitlis Devlet Hastanesi 2016 Yılı su ve besin kaynaklı bulaşıcı hastalık başvurularının değerlendirilmesi
Authors: ÖNEN Cihan , AKSOY Aziz , TEKİN Zakir , YÜREKLİ Emrah
Published: April 2019

Su ve
besin kaynaklı bulaşıcı hastalıklar, gelişmiş ve gelişmekte olan ülkelerde
morbidite ve mortaliteye artıran önemli bir halk sağlığı sorunudur. Bu yazıda
Bitlis Devlet Hastanesine 2016 yılında başvuran, su ve besin kaynaklı bulaşıcı
hastalık tanısı almış olgular değerlendirilmiştir.
DAMPAK NEGATIF ADIKSI PENGGUNAAN SMARTPHONE TERHADAP ASPEK-ASPEK AKADEMIK PERSONAL REMAJA
Authors: Utami Annisa Nurul
Published: April 2019

Perkembangan teknologi di era digital ini telah memperluas cakupan media elektronik smartphone sampai kepada kalangan remaja. Smartphone memiliki fungsi utama sebagai alat bantu komunikasi jarak jauh dan pencarian informasi melalui internet secara umum. Di luar itu, bagi remaja yang masih bersekolah ternyata kemunculan smartphone tidak hanya memberikan dampak positif bagi perkembangan kualitas capaian pendidikan mereka, tetapi juga berpotensi memberikan ragam dampak negatif. Dari itu, tinjauan sistematis ini mengumpulkan hasil studi ilmiah kuantitatif dan kualitatif mengenai dampak-dampak negatif adiksi smartphone terhadap aspek-aspek akademik personal remaja. Studi ini menggunakan pencarian dari dua database melalui penjelasan bentuk metasummary kualitatif. Sebanyak 10 studi terpilih berdasarkan kriteria seleksi. Hasil penelusuran studi-studi terpilih menunjukkan bahwa adiksi smartphone pada remaja sekolah menengah pertama dan sekolah menengah atas dapat beresiko menurunkan prestasi akademik, menurunkan keterlibatan akademik, mendorong munculnya perasaan tidak puas pada sekolah, meningkatkan perasaan cemas, dan memunculkan gejala depresi. Masalah perilaku lainnya yang ditemukan melalui studi terpilih dari adiksi smartphone adalah kerentanan remaja pada beban pikiran berlebihan, pengaturan perhatian, agresivitas aksi antisosial, kesulitan membangun identitas diri positif, dan peningkatan potensi aksi merusak diri. Dari semua dampak tersebut, bagian aspek akademik personal remaja yang paling banyak ditemukan yaitu memburuknya prestasi akademik. Perhatian pada dampak negatif adiksi smartphone terhadap aspek akademik personal remaja dapat memberikan informasi bagi orangtua, guru, dan para profesional dalam menyusun antisipasi kerugian akademik bagi remaja, seperti dalam menyusun program sosialisasi untuk mengedukasikan penggunaan smartphone secara bijak.
KEEFEKTIFAN KONSELING KELOMPOK COGNITIVE BEHAVIOR UNTUK MENINGKATKAN REGULASI DIRI SISWA SMP
Authors: Habsy Bakhrudin All
Published: April 2019

Self regulation is a process of self-regulation to set a mind and feeling to achieve a goal to be achieved. Self regulation determines student success, because students who have self-regulation can plan, evaluate, and control themselves. This study aims to determine the effectiveness of cognitive behavior group counseling can improve self-regulation of junior high school students. This study, using an experimental design with the Nonequivalent Control Group Design design. The data normality test results show that the control group is not normally distributed where the Sig.Asymp is smaller than 0.05. Whereas for the experimental group is normally distributed, where Sig.Asymp is greater than 0.05. Then it is obtained a hypothesis test that is appropriate for the control group using Wilcoxon test and for the experimental group using paired samples t test. Wilcoxon test results showed Sig.Asymp (2-tailed) of 0.080> 0.05, meaning that without giving counseling the Cognitive behavior group in the control group was not effective in improving student self-regulation, while for the paired samples t test test results showed Sig.Asymp ( 2-tailed) of 0.003 <0.05 means that the counseling behavior of Cognitive behavior groups in the experimental group is effective in enhancing student self-regulation. The research was carried out starting from April 2018 to January 2019, which took place at SMP Islam Mbah Bolong Jombang. Based on the results of the research, researcher gives suggestions for: 1) Teachers of Counseling Guidance, can be used as a reference that Cognitive behavior group counseling services can improve student self-regulation,  2) For further research: can apply Cognitive behavior counseling and can use different techniques in group counseling services so that they will gain a broader insight
Peluang Heterosis Hasil Persilangan Terkendali pada Bobot Umbi dan Kadar Kalium Ubi Jalar
Authors: Indriani Febria Cahya , Restuono Joko
Published: April 2019

Persilangan terkendali pada tanaman ubi jalar berpeluang untuk meningkatkan heterozigositas dibandingkan persilangan terbuka (open pollination). Penelitian bertujuan untuk mempelajari pola heterosis karakter bobot umbi per tanaman dan kadar kalium pada ubi jalar. Penelitian dilaksanakan di Poncokusumo, Malang, dan analisis kadar kalium di Laboratorium Kimia Tanah, Balai Penelitian Tanaman Aneka Kacang dan Umbi pada bulan Maret sampai Desember 2015. Bahan penelitian yang digunakan adalah benih F1 hasil persilangan terkendali dari enam kombinasi persilangan. Nilai heterosis diduga dengan membandingkan antara selisih F1 dengan rata-rata kedua tetua, sedangkan heterobeltiosis diduga dengan membandingkan antara F1 dengan tetua terbaik. Hasil penelitian menunjukkan adanya fenomena heterosis pada karakter bobot umbi per tanaman dan kadar kalium pada ubi jalar. Peluang heterosis untuk karakter bobot umbi per tanaman sebesar 16% dan heterobeltiosis 11%, sedangkan peluang heterosis kadar kalium sebesar 47% dan heterobeltiosis 21%. Varietas Beta 2 sangat potensial digunakan sebagai tetua untuk meningkatkan peluang heterosis bobot umbi per tanaman dan kadar kalium pada ubi jalar.
Kinetic Modeling of pH‐Dependent Molybdenum(VI) Adsorption and Desorption on Iron Oxide‐Coated Sand
Authors: Sun Wenguang , Selim H. Magdi
Published: April 2019

Core Ideas

Molybdenum(VI) sorption and kinetic rate are significantly reduced by increasing pH.

A Diffuse Layer Model simulated protonated monodentate complex was dominant at low pH.

A kinetic two‐site model successfully described Mo(VI) adsorption–desorption behavior.

Quantitative understanding of retention kinetics controlling molybdenum [Mo(VI)] on soil constituents such as iron oxide binding sites is crucial for accurately evaluating environmental risk of ground and surface water contamination. In this study, kinetic batch experiments were performed to investigate Mo(VI) adsorption–desorption behavior on iron oxide‐coated sand (IOCS) at different reaction conditions and time scale. Batch results indicated that adsorption of Mo(VI) on IOCS was highly nonlinear and kinetic, where both sorption and the extent of kinetics decreased with increasing solution pH. A two‐site model based on the heterogeneity of binding sites and variations of solution chemistry was developed to describe Mo(VI) adsorption and desorption on IOCS. The approach integrates kinetic nonlinear sorption into the surface complexation Diffuse Layer Model (DLM). Our results indicated that kinetic rate of non‐protonated monodentate complexes was much higher than that of protonated monodentate complexes. The kinetic model was capable of describing the experimental data with limited number model fitting parameters.
Design, Synthesis, Pharmacological Evaluation and Vascular Effects of Delphinidin Analogues
Authors: Legeay Samuel , Trân Kien , Abatuci Yannick , Justiniano Hélène , Lugnier Claire , Duval Olivier , Helesbeux Jean-Jacques , Faure Sébastien
Published: April 2019

Background:

Among polyphenolic compounds suggested to prevent cardiovascular diseases (CVDs)
and to explain the “French paradox”, the anthocyanidin delphinidin (Dp) has been reported to support at least
partly the vascular beneficial effects of dietary polyphenolic compounds including those from fruits and related
products as red wine. It has also been highlighted that Dp interacts directly with the active site of estrogen receptor
α (ERα), leading to activation of endothelial NO synthase (eNOS) pathway thus contributing to the prevention
of endothelial dysfunction in mice aorta. However, anthocyanidins have very low bioavailability and despite a
well described in vitro efficacy, the very high hydrophilicity and physicochemical instability of Dp might explain
the lack of in vivo reported effects.

Objective:

The aim of this study was to identify new Dp analogues with increased lipophilicity and vasorelaxation
potential by a chemical modulation of its structure and to characterize the signaling pathway notably in relation
with ERα signaling and nitric oxide (NO) production.

Method:

OCH3-substituted delphinidin analogues were obtained through the coupling of the corresponding acetophenones
with substituted benzaldehydes. Prediction of resorption of the flavylium derivatives was performed
with the calculated logP and induction of vasorelaxation was performed by myography on WT and ERαKO mice
thoracic aorta rings and compared to Dp. NO production was evaluated in vitro on human primary endothelial
cells.

Results:

Eight Dp analogues were synthesized including four new flavylium derivatives. Two compounds (9 and
11) showed a strong increase of vasorelaxation potential and a theoretically increased bioavailability compared to
Dp. Interestingly, 9 and 11 induced increased O2
- or NO endothelial production respectively and revealed a novel
NO-dependent ERα-independent relaxation compared to Dp. We suggested that this mechanism may be at least in
part supported by the inhibition of vascular cyclic nucleotide phosphodiesterase (PDEs).

Conclusion:

The current study demonstrated that pharmacomodulation of the Dp backbone by replacement of
OH groups by OCH3 groups of the A and B rings led to the identification and characterization of two compounds
(9 and 11) with enhanced physio-chemical properties that could be associated to higher permeability capability
and pharmacological activity for the prevention of CVDs compared to Dp.
Celastrol Protects RPE Cells from Oxidative Stress-Induced Cell Death via Activation of Nrf2 Signaling Pathway
Authors: Zhou Yeqi , Zhou Linbin , Zhou Kewen , Zhang Jingyue , Shang Fu , Zhang Xinyu
Published: April 2019

Purpose:

Oxidative stress to retinal pigment epithelial (RPE) cells and
inflammation are closely related to the pathogenesis of age-related macular
degeneration (AMD). Celastrol is a natural compound isolated from the root of
Tripterygium wilfordii. Celastrol has been shown to have potent anti-inflammatory and
anti-tumor effects in multiple disease models. The objective of this study was to test the
anti-oxidative effects of celastrol in RPE cells and to investigate the underlying
mechanisms.

Methods:

ARPE-19 cells were treated with hydrogen peroxide (H2O2) and menadione
alone or in combination with celastrol. Cell viability and apoptosis were examined by
CCK-8 and TUNEL assay, respectively. The expression of Nrf2 and its target genes,
such as GCLM and HO-1 was determined by Western blotting. The knockdown of Nrf2
was done by transfecting ARPE-19 cells with lentivirus encoding shRNA against Nrf2.
The knockdown efficiency was determined by real-time quantitative PCR and Western
blotting.

Results:

Treatment of ARPE-19 cells with celastrol significantly attenuated the toxic
effects of both H2O2 and menadione. Treatment with celastrol enhanced the expression
of transcription factor Nrf2 and its targets, GCLM and HO-1. Knockdown of Nrf2
expression by shRNA partially abolished the protective effects of celastrol. Chemical
inhibition of glutathione synthesis by L-buthionine-S,R-sulfoximine (BSO) completely
abolished the protective effects of celastrol against H2O2 and menadione-induced
damage. However, chemical inhibition of HO-1 activity by ZnPPIX did not reduce the
protective effects of celastrol.

Conclusion:

This study provides evidence that treatment of RPE cells with celastrol
shows potent protective effects against oxidative insults via activation of Nrf2 signaling
pathway and upregulation of GCLM expression. This finding suggests that celastrol
might be used as a potential therapeutic agent for oxidative stress-related eyes
diseases, such as AMD.
Exosome: An Emerging Source of Biomarkers for Human Diseases
Authors: Xu Li , Wu Long-Fei , Deng Fei-Yan
Published: April 2019

Exosomes are 30-120nm long endocytic membrane-derived vesicles, which are secreted by various types of cells and stably present in body fluids, such as plasma, urine, saliva and breast milk. Exosomes participate in intercellular communication. Recently accumulative studies have suggested that exosomes may serve as novel biomarkers for disease diagnosis and prognosis. Herein, we reviewed the biological features of exosomes, technologies for exosome isolation and identification, as well as progress in exosomal biomarker identification, highlighting the relevance of exosome to human diseases and significance and great potential in translational medicine.
A Robust Real Time Object Detection and Recognition Algorithm for Multiple Objects
Authors: Modwel Garv , Mehra Anu , Rakesh Nitin , Mishra Krishna K.
Published: April 2019

Background:

Object detection algorithm scans every frame in the video to detect the objects
present which is time consuming. This process becomes undesirable while dealing with real
time system, which needs to act with in a predefined time constraint. To have quick response we
need reliable detection and recognition for objects.

Methods:

To deal with the above problem a hybrid method is being implemented. This hybrid method
combines three important algorithms to reduce scanning task for every frame. Recursive Density Estimation
(RDE) algorithm decides which frame need to be scanned. You Look at Once (YOLO) algorithm
does the detection and recognition in the selected frame. Detected objects are being tracked
through Speed Up Robust Feature (SURF) algorithm to track the objects in subsequent frames.

Results:

Through the experimental study, we demonstrate that hybrid algorithm is more efficient
compared to two different algorithm of same level. The algorithm is having high accuracy and low
time latency (which is necessary for real time processing).

Conclusion:

The hybrid algorithm is able to detect with a minimum accuracy of 97 percent for all
the conducted experiments and time lag experienced is also negligible, which makes it considerably
efficient for real time application.
Evaluation of a Technology-Based Peer-Support Intervention Program for Preventing Postnatal Depression (Part 2): Qualitative Study
Authors: Shorey Shefaly , Ng Esperanza Debby
Published: April 2019

Background

Social support is known to reduce risks of postnatal depression (PND) and improve maternal emotional well-being. However, the Asian cultural context is often neglected when appraising maternal needs and mothers’ preferences for social support. While many preventive efforts have experimented with technology, professionals, and paraprofessionals in providing social support to mothers in need, most studies determined the effectiveness of their interventions through quantitative measurements of maternal outcomes. Experiences and feedback from both participants and administrators are rarely discussed, especially in an Asian setting.

Objective

The goal of the research was to evaluate the postnatal experiences of Asian mothers at risk of PND and the perceptions of peer volunteers regarding a technology-based peer-support intervention program (PIP).

Methods

A qualitative semistructured interview was conducted with 20 Asian mothers at risk of depression (10 from the control group and 10 from the intervention group) and 19 peer volunteers from a randomized controlled trial. The PIP included weekly correspondence between peer volunteers and mothers through any telecommunication means over 4 weeks. All interviews were approximately 30 to 60 minutes long, audiotaped, transcribed verbatim, and analyzed using thematic analysis. Study findings were reported according to the Consolidated Standards of Reporting Trials checklist.

Results

Two overarching themes comprising five subthemes were generated: postnatal experience (a bouncy ride, a way forward) and evaluation of the PIP (valuable, flexible, and supportive program; building blocks of a good relationship; and lessons learned and the road ahead). Mothers from both the control and interventions groups were generally satisfied with hospital care and the support received from family. They also shared similar breastfeeding challenges and needs for more informed decisions and follow-up support from the hospital. However, mothers who received the PIP tended to have more positive outlooks of their birth experiences. Overall, peer volunteers and mothers involved in the PIP found the PIP useful and expressed satisfaction with the program’s flexibility. They also shared their personal takeaways, the qualities of their friendships, and the need for extended correspondence time and recommended outreach to non–at-risk mothers.

Conclusions

The positive endorsement of the PIP by peer volunteers and mothers suggests the success of the PIP in maintaining positive maternal emotional well-being during the postpartum period. With the help of technology, hospitals can easily provide additional peer support to at-risk mothers in addition to existing standard care offered to these mothers.

Trial Registration

ISRCTN Registry ISRCTN14864807; http://www.isrctn.com/ISRCTN14864807

International Registered Report Identifier (IRRID)

RR2-10.2196/resprot.9416
Hypothermic Oxygenated Perfusion Versus Static Cold Storage for Expanded Criteria Donors in Liver and Kidney Transplantation: Protocol for a Single-Center Randomized Controlled Trial (Preprint)
Authors: Ravaioli Matteo , Maroni Lorenzo , Angeletti Andrea , Fallani Guido , De Pace Vanessa , Germinario Giuliana , Odaldi Federica , Corradetti Valeria , Caraceni Paolo , Baldassarre Maurizio , Vasuri Francesco , D'Errico Antonia , Sangiorgi Gabriela , Siniscalchi Antonio , Morelli Maria Cristina , Rossetto Anna , Ranieri Vito Marco , Cescon Matteo , Del Gaudio Massimo , Zanfi Chiara , Bertuzzo Valentina , Comai Giorgia , La Manna Gaetano
Published: April 2019

BACKGROUND

Extended criteria donors (ECD) are widely utilized due to organ shortage, but they may increase the risk of graft dysfunction and poorer outcomes. Hypothermic oxygenated perfusion (HOPE) is a recent organ preservation strategy for marginal kidney and liver grafts, allowing a redirect from anaerobic metabolism to aerobic metabolism under hypothermic conditions and protecting grafts from oxidative species–related damage. These mechanisms may improve graft function and survival.

OBJECTIVE

With this study, we will evaluate the benefit of end-ischemic HOPE on ECD grafts for livers and kidneys as compared to static cold storage (SCS). The aim of the study is to demonstrate the ability of HOPE to improve graft function and postoperative outcomes of ECD kidney and liver recipients.

METHODS

This is an open-label, single-center randomized clinical trial with the aim of comparing HOPE with SCS in ECD kidney and liver transplantation. In the study protocol, which has been approved by the ethics committee, 220 patients (110 liver recipients and 110 kidney recipients) will be enrolled. Livers and kidneys assigned to the HOPE group undergo machine perfusion with cold Belzer solution (4-10°C) and continuous oxygenation (partial pressure of oxygen of 500-600 mm Hg). In the control group, livers and kidneys undergoing SCS are steeped in Celsior solution and stored on ice. Using the same perfusion machine for both liver and kidney grafts, organs are perfused from the start of the back-table procedure until implantation, without increasing the cold ischemia time. For each group, we will evaluate clinical outcomes, graft function tests, histologic findings, perfusate, and the number of allocated organs. Publication of the results is expected to begin in 2021.

RESULTS

Dynamic preservation methods for organs from high-risk donors should improve graft dysfunction after transplantation. To date, we have recruited 108 participants. The study is ongoing, and recruitment of participants will continue until January 2020.

CONCLUSIONS

The proposed preservation method should improve ECD graft function and consequently the postoperative patient outcomes.

CLINICALTRIAL

ClinicalTrials.gov NCT03837197; https://clinicaltrials.gov/ct2/show/NCT03837197 ; Archived by WebCite® at http://www.webcitation.org/76fSutT3R

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/13922
The Effect of the Interactive Mobile Health and Rehabilitation System on Health and Psychosocial Outcomes in Spinal Cord Injury: Randomized Controlled Trial (Preprint)
Authors: Kryger Michael Alan , Crytzer Theresa M , Fairman Andrea , Quinby Eleanor J , Karavolis Meredith , Pramana Gede , Setiawan I Made Agus , McKernan Gina Pugliano , Parmanto Bambang , Dicianno Brad E
Published: April 2019

BACKGROUND

Individuals with spinal cord injury (SCI) are at risk for secondary medical complications, such as urinary tract infections (UTIs) and pressure injuries, that could potentially be mitigated through improved self-management techniques. The Interactive Mobile Health and Rehabilitation (iMHere) mobile health (mHealth) system was developed to support self-management for individuals with disabilities.

OBJECTIVE

The main objective of this study was to determine if the use of iMHere would be associated with improved health outcomes over a 9-month period. A secondary objective was to determine if the use of iMHere would be associated with improved psychosocial outcomes. Phone usage, app usage, and training time data were also collected to analyze trends in iMHere use.

METHODS

Overall, 38 participants with SCI were randomized into either the intervention group who used the iMHere system and received standard care or the control group who received standard care without any technology intervention. Health outcomes were recorded for the year before entry into the study and during the 9 months of the study. Participants completed surveys at baseline and every 3 months to measure psychosocial outcomes.

RESULTS

The intervention group had a statistically significant reduction in UTIs (0.47 events per person; P=.03; number needed to treat=2.11). Although no psychosocial outcomes changed significantly, there was a nonsignificant trend toward a reduction in mood symptoms in the intervention group compared with the control group meeting the threshold for clinical significance. Approximately 34 min per participant per month were needed on average to manage the system and provide technical support through this mHealth system.

CONCLUSIONS

The use of the iMHere mHealth system may be a valuable tool in the prevention of UTIs or reductions in depressive symptoms. Given these findings, iMHere has potential scalability for larger populations.

CLINICALTRIAL

ClinicalTrials.gov NCT02592291; https://clinicaltrials.gov/ct2/show/NCT02592291.
Back to the Future: Achieving Health Equity Through Health Informatics and Digital Health (Preprint)
Authors: Brewer LaPrincess C , Fortuna Karen L , Jones Clarence , Walker Robert , Hayes Sharonne N , Patten Christi A , Cooper Lisa A
Published: April 2019

UNSTRUCTURED

The rapid proliferation of health informatics and digital health innovations has revolutionized clinical and research practices. There is no doubt that these fields will continue to have accelerated growth and a substantial impact on population health. However, there are legitimate concerns about how these promising technological advances can lead to unintended consequences such as perpetuating health and health care disparities for underresourced populations. To mitigate this potential pitfall, it is imperative for the health informatics and digital health scientific communities to understand the challenges faced by disadvantaged groups, including racial and ethnic minorities, which hinder their achievement of ideal health. This paper presents illustrative exemplars as case studies of contextually tailored, sociotechnical mobile health interventions designed with community members to address health inequities using community-engaged research approaches. We strongly encourage researchers and innovators to integrate community engagement into the development of data-driven, modernized solutions for every sector of society to truly achieve health equity for all.
Angola, Moçambique e Cabo Verde: Uma Introdução à Prosa de Ficção da África Lusófona
Authors: Silva Maurício
Published: April 2019

O presente artigo procura analisar a relação entre identidade cultural e consciência nacionalista nas literaturas africanas lusófonas, principalmente considerando as perspectivas estética (Sartre) e moral (Marcuse).
José Eduardo Agualusa e o cânone literário angolano
Authors: Bach Carlos Batista
Published: April 2019

A proposta desse trabalho é discutir de que forma se pode perceber a construção de um cânone literário angolano e a inserção do autor José Eduardo Agualusa nesse cânone. Nesse caminho, é preciso que se faça uma breve exposição do que se conhece da história de Angola, país que só se tornou independente em 1975, tendo, até então, sido colônia de Portugal.
Cronotopias multiculturais e polifonia em As mulheres do meu pai, de José Eduardo Agualusa
Authors: Fornos Jose Luis
Published: April 2019

O presente ensaio visa à análise do romance As mulheres do meu pai (2009), do escritor angolano José Eduardo Agualusa, tendo como reflexão teórica os estudos de M. Bakhtin, Homi Bhabha, Stuart Hall e Boaventura de Sousa Santos. Recorre-se às categorias de raça e de hibridismo, considerando-as numa perspectiva histórica e geográfica. Aponta para a idéia de um cosmopolitismo multicultural como utopia das novas relações internacionais e sociais, através dos princípios de uma hermenêutica diatópica.
Os papéis do inglês e a busca pelas identidades pós-coloniais
Authors: Torre Melissa Cobra
Published: April 2019

Este artigo apresenta uma discussão sobre a questão identitária no período pós-colonial, refletindo sobre a condição fronteiriça daqueles sujeitos que se encontram entre duas culturas, compartilhando de duas identidades. Para isso, este trabalho propõe uma análise do romance Os papéis do inglês, do angolano Ruy Duarte de Carvalho, pois acredita-se que esta obra literária seja um exemplo de romance pós-colonial, em que a questão identitária é colocada como elemento crucial na narrativa.
Budapeste de Chico Buarque e o fenômeno pós-moderno
Authors: Camelo Franciano
Published: April 2019

Este artigo busca evidenciar algumas questões centrais do romance Budapeste e discutir em que medida elas estão relacionadas ao fenômeno pós-moderno. Para tanto, o presente estudo apoia-se nas contribuições teórico-críticas de autores como Fredric Jameson, Josefina Ludmer, Marc Augé e Stuart Hall. O que se pode constatar é que a identidade ocupa lugar central em Budapeste. Ademais, essa categoria é formalizada de modo a levantar uma série de outros temas, também relacionados ao pós-moderno, a saber, os limites entre o real e o ficcional, a noção de estilo e a fragmentação do sujeito.
O corpo-abismo: representação imagética de Maria Eduarda de Os Maias
Authors: Dos Santos Melissa Rubio
Published: April 2019

O presente artigo visa problematizar a representação imagética da personagem Maria Eduarda da minissérie Os Maias, uma (re)leitura imagética, baseada no romance homônimo de Eça de Queiroz (1888). O ponto de partida do estudo é a investigação da caracterização da personagem Maria Eduarda na narrativa visual (minissérie). O estudo será conduzido a partir das seguintes perguntas: Como Maria Eduarda é representada na minissérie? O que há por trás das escolhas na composição das imagens (figurino) dessa personagem? O que a corporeidade de Maria Eduarda expressa? Como se estabelece a relação entre corpo, poder e silêncio?
A busca da origem em Natália, de Helder Macedo
Authors: Da Silva Nunes Bruna
Published: April 2019

Este artigo trata da busca da origem no livro Natália, de Helder Macedo, pela narradora/protagonista que dá título à obra. Para isso, ele se fundamenta em teorias da psicanálise que trabalham com a temática da importância do olhar materno.