bluuebunny/crossref_metadata_2025 huggingface dataset:
User's guide to sample size estimation in diagnostic accuracy studies
Authors: Akoglu Haldun
Published: September 2022

Sample size estimation is an overlooked concept and rarely reported in diagnostic accuracy studies, primarily because of the lack of information of clinical researchers on when and how they should estimate sample size. In this review, readers will find sample size estimation procedures for diagnostic tests with dichotomized outcomes, explained by clinically relevant examples in detail. We hope, with the help of practical tables and a free online calculator (https://turkjemergmed.com/calculator), researchers can estimate accurate sample sizes without a need to calculate from equations, and use this review as a practical guide to estimating sample size in diagnostic accuracy studies.
Evaluation of In vitro Activity of Tigecycline against Multidrug-Resistant Clinical Isolates
Authors: Wilson Livya A. , Kuruvilla Thomas S.
Published: September 2022

Introduction:

Multiple drug resistance (MDR) of the bacteria is an issue across any health-care setting worldwide. This leads to prolonged hospital stay and high cost of treatment. One must be cautious to use reserve drugs such as imipenem, meropenem, colistin, polymyxin, and tigecycline. Tigecycline is a mainstay to treat emerging single or MDR pathogens. The study was conducted to assess the in vitro sensitivity of tigecycline to MDR isolates and to compare the sensitivity of Kirby–Bauer (KB) disc-diffusion method with the Epsilometer (E-test) against various MDR clinical isolates.

Materials and Methods:

This prospective study was done from January 2019 to 2020 on MDR isolates from clinical specimens. The isolates were tested for their antibiotic sensitivity to tigecycline by KB and E-test method to know the minimum inhibitory concentration (MIC) of tigecycline. Statistical data were analyzed by the percentage method.

Results:

Tigecycline showed a higher in vitro sensitivity against multidrug-resistant isolates in our study. Among the 89 MDR isolates obtained, 38 (42.7) were found to be sensitive to tigecycline by the KB diffusion and 67 (75.3) were sensitive by the E-test method.

Conclusions:

Tigecycline is a reserve antibiotic against MDR organisms, especially useful to treat coinfections of Gram-positive and Gram-negative superbugs. The E-test was found to be far superior to the KB method to detect in vitro activity and the results of this test will guide the clinician to judiciously use this antibiotic in their day-to-day practice.
A Case of Post Covid-19 Pulmonary Cysts and Pneumatoceles
Authors: Rehman Taseena Banu , Kamath Vasantha , Vinay R. B. , Vardarajulu Reginald
Published: September 2022

With time, newer pulmonary and extrapulmonary manifestations of postacute coronavirus disease (COVID) syndrome are being reported. This is a case report of a 67-year-old diabetic and hypertensive female who presented with persistent progressive cough and breathlessness 2 months after she was diagnosed and treated for COVID-19. The patient was admitted and worked up as a case of postacute COVID syndrome. She was radiologically detected to have diffuse, large, multiple cystic air-filled cavitary lesions all over the lungs bilaterally. Despite adequate treatment and support with oxygen supplementation, the patient’s condition kept on worsening, and she was thus referred to a higher center for cardiothoracic vascular surgical intervention.
Significance of Pure Sensory Manifestations in Estimating Electromyography Results in Cervical Radiculopathy
Authors: Ercan Merve Bahar , Kuruoglu Hidayet Reha
Published: September 2022

Background:

The sensitivity of electromyography (EMG) in cervical radiculopathy (CR) is reportedly higher in patients with objective neurological findings, but many patients are sent to the EMG laboratory with only pain and paresthesias.

Aims:

We aimed to assess the diagnostic contribution of EMG in patients with sensory manifestations without objective neurological deficits.

Settings and Design:

The files of patients with neck pain radiating to the shoulder and arm on the same side referred to the EMG Laboratory were retrospectively evaluated. EMG findings of those with pure sensory manifestations were compared with the results obtained from patients with objective neurological deficits.

Subjects and Methods:

Patients with subjective sensory manifestations were separated into two groups according to the specificity of the presenting symptoms, who were compared with subjects with neurological findings in the upper extremity. Clinical diagnoses of the patients were compared with the electrodiagnostic testing results.

Statistical Analysis:

Categorical variables were analyzed with multi-span Chi-square test, while individual groups were compared utilizing Fisher's exact test. One-way analysis of variance was employed to assess the significance of group differences for quantitative values.

Results:

EMG rarely confirmed CR in patients with purely sensory symptoms. Some of these patients were found to have unexpected peripheral neuropathy syndromes. Both paraspinal and limb muscle EMG abnormalities indicative of CR were not only more common, but also helpful in localization in patients with objective clinical findings.

Conclusions:

CR patients presenting only with pain and paresthesias even in a specific dermatomal distribution usually demonstrate no abnormalities in EMG examination. However, some of these patients harbor unsuspected entrapment neuropathies.
The Introduction of Neuroscience in Spain through the Work of Luis Simarro
Authors: López-Muñoz Francisco , Pérez-Fernández Francisco
Published: September 2022

Background:

The figure of Luis Simarro Lacabra is not well-known outside Spain, but within the country became a character of special scientific and public importance. Luis Simarro, a person of a marked progressist spirit, not only was involved from his youth for in political matters, showing great interest in the modernization of a nation anchored in traditionalism, but also transferred this way of thinking to his professional work as a doctor, neurologist, histologist, psychiatrist, psychologist, and teacher.

Methods:

The authors gathered biographic story of Simarro and summarized his work in microscopic work in neuroscience and the development of experimental psychology.

Results:

Simarro would become, for his own merit, one of the great founders of Spanish neuroscience, to which he made great contributions together with Santiago Ramón y Cajal. He was also the first professor of experimental psychology at Spanish University and developed an interesting political and institutional work. In fact, his lack of international recognition is mainly due to the fact that Luis Simarro, despite his great talent, was not especially prone to publishing the scientific works. Therefore, his neurological findings, sometimes, were to be unjustly attributed to other colleagues.

Conclusion:

In this article, we have provided a brief profile of the figure of Simarro with the intention of projecting the importance of his figure of it beyond Spanish borders.
The Relationship between Executive Functions and Interoceptive Awareness in the Elderly with Perceived Feelings of Loneliness
Authors: Choudhury Arpita Roy , Halder Susmita
Published: September 2022

Objectives:

Older adults are more vulnerable to perceived feelings of loneliness which may lead to depression, cognitive decline, and an overall decrease in their quality of life. In the present study, the main objective was to compare executive functions and interoceptive awareness between the elderly with and without perceived feelings of loneliness.

Methods:

In the study, we recruited a sample of 100 study subjects (50 individuals with perceived feelings of loneliness and 50 healthy controls). UCLA 3-Item Loneliness Scale was used as a screening tool for loneliness. Multidimensional Assessment of Interoceptive Awareness, Stroop Test, N Back Test (verbal and visual), and Wisconsin Card Sorting Test were used as measures of interoceptive awareness and executive functioning, respectively.

Results:

Significant difference was found between both the groups in working memory (p< 0.05) and set shifting ability (p< 0.01). In interoceptive awareness, significant difference was found between both the groups in the domains of significantly high on not distracting (t= 5.723,p< 0.01), significantly less on not worrying (t= 2.028,p< 0.05), significantly less on body listening (t= 2.302,p< 0.05), and significantly less on trusting (t= 4.630,p< 0.01).

Conclusion:

To understand the possible neuropsychological mechanism of loneliness may help conceptualize a better intervention plan for those with perceived feelings of loneliness to prevent progression to severe psychological problems and cognitive decline.
A Journal Is Always a Work in Progress
Authors: Alderman Chris
Published: September 2022

Periodically it is important for any organization to review its operations and performance, gathering data to analyze, and dedicating some careful thought to the way in which it has been executing its operations. One critical aspect of this process (probably the most important) is self-reflection about the extent to which the group has been addressing the needs of the stakeholders. The readers of a
journal may not be aware of these processes, but almost all periodic publications will engage in exactly these activities; in some aspects, they will do them periodically, and in others ”almost continually. One of these is the semi-annual practice of a readership survey, which this journal recently completed.
The Story of Our Place in Pharmacy: Reflections on The Senior Care Pharmacist
Authors: Worz Chad
Published: September 2022

Beginning in print form as The Consultant Pharmacist, foundational members established a peer reviewed, scientific journal aimed directly at those pharmacists working as consultant pharmacists in predominantly skilled nursing environments. It was a rapid rise and a resounding success. Over time, as the population shifted toward older people and consultant pharmacists took all their experience and skill and followed individuals into new settings of care like assisted living, the community, and the home, the journal moved forward with them. It published articles and research on the impact of pharmacists and pharmacies with specialized services that delivered quality care not only in a skilled nursing facility, but also now in assisted living, in group settings, in community health care settings, and to individuals in their homes.
The US Federal Government's Role in Insulin Pricing
Authors: Baldwin Paul
Published: September 2022

Those of you who have been in the health care professions for more than two decades may recall a time when the cost of insulin was not among the top five issues people mentioned when conversations turned to health care policy. Times have changed, and now it is a major topic of public concern.
Pouk latinščine v javni osnovni šoli v letih 1958–2022 in kako naprej
Authors: Pirkmajer Slokan Aleksandra
Published: September 2022

Besedilo v nadaljevanju obravnava zgodnje učenje latinščine. Osredotoča se na zanj bistvene višje štiri osnovnošolske razrede, na tako imenovano predmetno stopnjo (starost učencev od 11 do 15 let, ob zgodnejšem vstopu v šolo od 10 do 14 let). To širša javnost slabo pozna, vse prepogosto jo dojema – naj bo večina z izkušnjo nižje klasične gimnazije ali poznejšega štiriletnega osnovnošolskega latinskega programa a priori izvzeta – kot nezanimivo oziroma, kako napačno, kot programsko manj pomembno od razredne ali srednješolske stopnje. Vsakokratna šolska oblast pa se, nasprotno, dobro zaveda pomena tega starostnega razdobja, ko se začenjajo ustvarjati zametki celostnega pogleda na svet in samega sebe, ter skuša zanj uvesti enovit, po svoji meri ukrojen šolski sistem, pri čemer je vedno znova na udaru tudi pouk klasičnih jezikov.
Predmeti antičnih kultur Bližnjega vzhoda v starinoslovnih zbirkah dvorca Jelšingrad
Authors: Čakš Orač Lucija , Ciglenečki Jan
Published: September 2022

Dvorec Jelšingrad (Erlachstein), ki se nahaja na severozahodnem obrobju Šmarja pri Jelšah, je bil v sredini 19. stoletja deležen prenove vzhodnega dela stavbe, interierjev in parka po vzorih mavrske in orientalske arhitekture. Za novo eksotično podobo je bil zaslužen tedanji lastnik Rudolf Oskar Gödel-Lannoy (1814–1883), ki je med svojo dolgoletno diplomatsko kariero v Egiptu, na Bližnjem vzhodu in Balkanu načrtno zbiral antikvitete. Ob vrnitvi v domovino jih je v svojem dvorcu razstavil v treh novo nastalih orientalskih dvoranah, kar se v sočasnih virih omenja kot “orientalni muzej”. Iz popisa predmetov, ki so jih leta 1943 v dvorcu zasegli Nemci in prenesli v Pokrajinski muzej Maribor, je razvidno, da je Lannoyjeva zbirka starin vključevala številne predmete iz starega Egipta, Mezopotamije, Grčije in Rima. Z izjemo staroegipčanskega fragmenta Merimosejevega sarkofaga iz 18. dinastije, ki ga danes hranijo v Narodnem muzeju v Pragi, v dosedanjih raziskavah vsebina Lannoyjevih starinoslovnih zbirk še ni bila deležna strokovne pozornosti. Pričujoči prispevek se osredotoča na jelšingrajsko zbirko mezopotamskih predmetov, tj. cilindričnih pečatov, pečatnih kamnov, živalskih amuletov in glinenega stožca kralja Gudea iz Lagaša, ki jih danes hranijo v depoju arheološke zbirke Univerzalnega muzeja Joanneum v Gradcu.
Symmetry classification of scalar autonomous Ito stochastic differential equations with simple noise
Authors: Gaeta Giuseppe , Rodriguez Miguel Angel
Published: September 2022

It is known that knowledge of a symmetry of a scalar Ito stochastic differential equations leads, thanks to the Kozlov substitution, to its integration. In the present paper we provide a classification of scalar autonomous Ito stochastic differential equations with simple noise possessing symmetries; here "simple noise" means the noise coefficient is of the form $\s (x,t) = s x^k$, with $s$ and $k$ real constants. Such equations can be taken to a standard form via a well known transformation; for such standard forms we also provide the integration of the symmetric equations. Our work extends previous classifications in that it also consider recently introduced types of symmetries, in particular standard random symmetries, not considered in those.
Way to Use Western Knowledge in China in English Teaching from the Perspective of Social Culture Theory
Authors: Li Chengyun
Published: September 2022

According to the innovative demand and trend of English teaching in the new era, the application of the existing English teaching model has been difficult to achieve the expected teaching effect. Therefore, this paper introduces the sociocultural theory of psycholinguistics to study its application in English teaching. From the Angle of sociocultural theory, this paper discusses how to use western knowledge to improve the effect of English teaching in Chinese colleges and universities.
CONCEPT OF AJIRNA IN AYURVEDA & ITS ROLE IN THE PATHOGENESIS OF GRAHNI ROGA -A REVIEW
Authors: Rohilla Dr.Prayasha , Saini Dr. Shri Ram
Published: September 2022

Ayurveda is an old traditional medical science that focuses on disease treatment and prevention. Ayu (long life), Bala (strength), and Varna (complexion) are all influenced by Agni's state. Because Agni is located in the Jathara(Stomach and Intestine), which digests and metabolises food and aids in body growth. All ailments are caused by inadequate, excessive, or irregular food digestion, which is referred to as Mandagni, Tikshnagni, or Vishamagni, respectively. When Agni is not functioning properly, food is not digested properly, and the undigested food ferments, acting as poison in the body. It’s called Ama. Ama Utpatti leads to Grahani Dosha. Ajirna refers to dyspepsia caused by disrupted Agni functions (indigestion). The most prominent source of Ama formation is Ajirna, which favours genesis illnesses. Agnimandya is an important component of the disease Grahani Dosha's Samprapti. Agni might be disrupted by an unpredictable lifestyle and a strange food. The first step in management is to eliminate the etiological cause. Unreliable seasonal regimen adherence, mental disturbance, and stress may all play a role in the progression of the Ajirna syndrome.
IMPORTANCE OF ‘RAKTA DHATU’ IN SHALYATANTRA ACCORDING TO ‘SUSHRUT SAMHITA’
Authors: Patel Dr. Mehabub H. , Banarase Dr. Mrs. Madhavi S.
Published: September 2022

Ayurved is an ancient science which is described in eight divisions like kaya, bal, griha, urdhvang (Shalakya )shalya ,Danshtra( agad,) Jara (rasayan) and vrushya (vajikaran). Among brihat-trayi Sushrut Sanhita is basic prime reference book of Shalya Tantra . Dhatus are very important, as they play important functions of Dharana and Poshana.. Sushrut has given due importance to only rakta dhatu in various context .Chief functions of Rakta dhatu is to keep individual alive . It is one of the dash pranayatan which circulates prana . Rakta in various forms like fenbhut, prasadbhut participates in the organogenesis , types of various diseases like vidradhi, visarpa, arsha, vranshoth and many more diseases are described according to rakta vitiations. In various surgical and Para surgical procesures Rakta has given importance. So this study on Importance of Rakta dhatu in Shalya Tantra according to Sushrut Sanhita is designed.
A REVIEW ARTICLE – PANCHAKARMA (DETOXIFICATION) SHODHAN KARMA
Authors: Ragad Dr.Shriram Shivajirao
Published: September 2022

Panchakarma is a specialty of Kayachikitsa (medicine). Pancha means "five" and Karma means "action", so Panchakarma means five actions. Panchakarma (five main biopurification therapies) a) Vamana, b) Virechana, c) Basti, d) Nasya, e) Raktastrav. These five procedures serve to cleanse the body internally in the closest possible way. In this article we discuss detoxification related to Ayurvedic Samhita.
INTRODUCTION OF ABHYANGA AND SNEHA YUKTA AAHAR IN GYM GOING PEOPLE IS NEED OF THE HOUR.
Authors: Gedam Dr. Sonia B. , Phule Dr. Nilesh M.
Published: September 2022

The Ayurvedic system of medicine uses a comprehensive approach to prevent and promote a healthy life by incorporating specific procedures and therapies into daily activities, like a to do list on a daily basis (Dinacharya), things to do and to consume in every rutu (season) i.e. Rutucharya, the way to behave in the society (Sadvrutta) etc…Considering every aspect for a person to be healthy.Aim – To study how important is abhyanga and sneha is for our body. Objective – To emphasize on benefits of abhyanga and intake of sneha and how it will be beneficial for the gym going people. Material and methods – More about Abhyanga and Sneha from Ayurvedic texts/Samhita. Discussion – Why it is necessary for gym going people to intake sneha and do Abhyanga. Conclusion – Abhyanga and sneha yukta aahar should be included in the daily regimen of the gym going people who do excessive exercise, so that they would remain healthy and won’t face any silent diseases in future.
MEDICO-LEGAL CARE FOR RAPE VICTIM-A REVIEW
Authors: MEHER DR. NEHA DEVIDAS , SUPUGAD DR. VIKRAM
Published: September 2022

The rape victim faces legal, psychological, and medical issues. In order to respond to all her needs, the physician must be aware of the legal questions to be answered in the record, the patient's psychological needs in this high stress situation, and the medical problems that are likely to arise. Government guidelines are essentially aimed at doctors who might one day be called upon to handle female victims of sexual assault / rape in the course of their duty whether in a government hospital or even a private one. As is known rape law has been made more stringent with zero tolerance for offenders and govt. guideline is to ensure a sensitive and humane approach to such victims, their proper treatment apart from attending or treating doctors responsibility and duty in recording and documenting the medical aspects in order that such cases when they come up before the criminal justice system are not found wanting in the quality of evidence produced by the prosecution during trial.
Extension of the DEMATEL Method for Multi-Criteria Market Segment Evaluation
Authors: Raju Shathaboina , Ramachandran M , Raja Chandrasekar , Mani Malarvizhi
Published: September 2022

When evaluating different market segments Segment size and growth segment structure Charisma and company objectives and resources are the three Factors Company should consider. Demographics, psychology, behavior, and geography are considered to be the four main types of market segmentation. However there are many strategies that you can use. In four main categories there are many differences. Here are several methods that can be done. Like check out. The decision-making test and evaluation laboratory (DEMATEL) is considered to be an effective method for identifying the cause-effect chain components of a complex system. It deals with the evaluation of interrelated Relationships between factors and by visual layout model Identify the important ones. In this paper we used DEMATEL for ranking the DEMATEL method is the most ideal solution Short-distance Evaluation Parameters in Segment factors, Competition, Technological factors, Socio-political factors, Financial and economic factors Use Attention deficit from the result it is seen that Competition is got the first rank whereas is the Financial and economic factors is having the Lowest rank
Variables personales y contextuales predictoras de salud mental en adolescentes: estrés, ansiedad, depresión e impulsividad
Authors: Morales Rodríguez Marisol , Díaz Barajas Damaris
Published: September 2022

El objetivo fue describir la salud mental en adolescentes a partir de los niveles de depresión, ansiedad, estrés e impulsividad y determinar la influencia que ejerce sobre ellas, la autoeficacia y la resiliencia, así como variables contextuales. Se basa en una metodología cuantitativa, diseño no experimental, transversal, alcance descriptivo-correlacional. Participaron 565 adolescentes de entre 12 y 21 años (M=16.9; D.E.=5.1) Se utilizaron las escalas Autoeficacia general, Resiliencia Connor y Davidson Ansiedad de Beck, Escala UPPS-P de impulsividad para niños y adolescentes, Escala de Depresión para adolescentes de Birleson, DASS-21-Subescala de estrés, las cuales se aplicaron mediante un formulario online, previo consentimiento informado. Los resultados muestran un predominio de niveles medio-altos en ansiedad y predominantemente altos en depresión, estrés e impulsividad. Las correlaciones de autoeficacia y resiliencia con las variables de salud mental fueron negativas, entre moderadas y bajas. El modelo de regresión lineal explicó la varianza de la depresión, impulsividad, ansiedad y estrés por influencia de la resiliencia, y solo de las dos primeras por la autoeficacia. El sexo, la edad y escolaridad influyen sobre la la ansiedad, depresión e impulsividad, además de las anteriores, el tipo de escuela, la modalidad de enseñanza y la estructura familiar incluyen en el estrés. Se concluye que los adolescentes presentan alteraciones en su salud mental que se ve reflejado en altos índices de depresión, impulsividad y manejo ineficiente del estrés e índice medio-alto en ansiedad. La resiliencia predice mayormente las variables de salud mental, actuando como un factor protector.
rebeliones lideradas por Calchaquí y Viltipoco (Gobernación del Tucumán, virreinato del Perú, siglo XVI)
Authors: Hopkins Cardozo Miguel Nicolás
Published: September 2022

Viltipoco y Calchaquí son los nombres de dos líderes indígenas que permanecen vivos en la memoria colectiva de las provincias argentinas de Jujuy y Salta. Sus nombres son reivindicados por organizaciones indígenas, son mencionados en el folklore, hay barrios, calles y monumentos que los recuerdan. Son una referencia ineludible para la historiografía del Tucumán colonial, pero, paradójicamente, es muy poco lo que sabemos de ellos. En este trabajo propongo recuperar lo poco que sabemos acerca de estos dos líderes indígenas partiendo de lo que la historiografía ha escrito sobre ellos, proponiendo una perspectiva regional, que trascienda el localismo que relaciona a Viltipoco con Jujuy y a Calchaquí con Salta. A partir de allí propongo plantear o recuperar hipótesis para tener en cuenta en estudios posteriores que contemplen los vínculos regionales que estas rebeliones visibilizan, creando un diálogo entre la historiografía de los valles Calchaquíes, la puna y quebrada jujeñas y Atacama.
Sumeru
Authors: Чандра Л.
Published: September 2022

Статья посвящена иконографии священной горы Сумеру и расположенных на ее территории мандал. Перевод статьи Локеша Чандры из «Словаря буддийской иконографии» выполнен С.М. Белокуровой.

The article is devoted to the iconography of the sacred mountain Sumeru and the mandalas located on it. The translation of Lokesh Chandra's article from the Dictionary of Buddhist Iconography was made by S.М. Belokurova.
Sweet Plant Proteins and Their Recombinant Production
Authors: YAZDANİAN ASR Shokoufeh , YÜKSEL Nergiz , İÇİER Seyhan , KAPLAN TÜRKÖZ Burcu
Published: September 2022

There is a growing interest and increasing awareness of consumers towards natural food products, therefore there is a shift in food industry to produce foods with natural ingredients. On the other hand, high amount of sweetener use in food industry is another health concern. An interesting group of natural sweeteners are sweet proteins, which have hundreds/thousands times higher sweetness than sucrose. Sweet proteins have high sweetness but low calorie values and are of interest as they can be used as healthy alternatives to natural or artificial sweeteners. Known plant sweet proteins are produced by tropical plants and this limits the amount of protein that can be obtained. In order to increase the amount of protein, many studies have been carried out on the recombinant production of plant sweet proteins using different expression systems. In this article, sources, types, physicochemical and structural properties of sweet plant proteins and studies on their recombinant production are reviewed with insights to future studies.
Thermal Conductivity and Thermal Rectification in Various Sequences of Monolayer Hexagonal Boron Nitride/Aluminum Nitride Superlattice Nanoribbons
Authors: KARAASLAN Yenal
Published: September 2022

In this study, the thermal transport properties for various geometries of monolayer h-BN/h-AlN superlattice nanoribbons are investigated using non-equilibrium molecular dynamics simulations. In this context, the lattice thermal conductivities of the superlattice nanoribbons are obtained for different period lengths, geometries, sample lengths, and temperatures. Results reveal that a decrease in the thermal conductivities of superlattice nanoribbons when compared with those of the pristine nanoribbons, the lattice thermal conductivities decrease with decreasing sample lengths and increasing temperatures, also the formation of the extremum points resulting from the competition between wave-like and particle-like phonon transport in the thermal conductivity of superlattice nanoribbons with the change of the period lengths. Moreover, superlattice nanoribbons with different geometries are created to connect the h-BN/h-AlN interface, and it is observed that there is a difference between the thermal conductivities calculated in the reverse directions. This difference leads to thermal rectification in the superlattice structures. As the asymmetry between thermal contact areas increases especially at low temperatures, it is found out the thermal rectification ratio increases.
On Travelling Wave Solutions of Dullin-Gottwald-Holm Dynamical Equation and Strain Wave Equation
Authors: TÜLÜCE DEMİRAY Şeyma , DAVARCI YALÇIN Merve
Published: September 2022

In this study, extended trial equation method (ETEM) is implemented to obtain exact solutions of the Dullin-Gottwald-Holm Dynamical equation (DGHDE) and the strain wave equation. We constitute some exact solutions such as soliton solutions, rational, Jacobi elliptic, periodic wave solutions and hyperbolic function solutions of these equations via ETEM. Then, we present results that we obtained by using this method.
Topographic, Morphological and Morphometric Investigation of Mandible in Norduz Sheep
Authors: DALGA Semine , AYDIN Uğur , ÇAL Tansel
Published: September 2022

In order to contribute to animal welfare, veterinary maxillofacial surgery is one of the fields of science that requires deep anatomical knowledge about the region. Therefore, in this study, it was aimed to define the mandible by using macroanatomical, morometric and topographic methods to understand the morphophysiology of the mandible in Norduz sheep. Norduz sheep mandibles of 10 male animals were used. Mandibles were first examined with classical morphometric and topographic methods. It was seen that the mandible consisted of corpus, ramus and angulus parts. It was observed that the foramen mentale was oval and round in shape and in different numbers on the lateral edge of the mandible. It was observed that the foramen mandible was elliptical. According to the statistical analysis, mandible length was measured as 149.12±4.75 mm on the right side and 148.12±4.50 mm on the left side in Norduz sheep. Mandible height was analyzed as 160.81±4.72 mm on the right side and 160.74 mm on the left side. The distance of the foramen mandible to the infradental space was 127.85±4.62 mm on the right and 125.31±4.11 mm on the left. Diastema length was analyzed as 38.05±1.34 on the right side and 40.87±2.81 on the left side. The length of the premolar and molar teeth on the margo alveolaris of the mandible was 56.69±2.38 mm on the right side and 54.13±2.73 mm on the left side. The distance of the foramen mentale to the gonion caudale was analyzed as 118.34±4.22 mm on the right and 118.90±4.12 mm on the left. According to the statistical analysis, L17 measured over the right and left mandibles was statistically significant (p
Utilization of Demolition Waste for Treatment of Acid Mine Drainage and Immobilization of Heavy Metals Released from Copper Flotation Tailings
Authors: TOZSİN Gülşen , KOÇ Ercüment , YAYLALI Banu , DEVECİ Hacı
Published: September 2022

In this study, the treatment of acid mine drainage (AMD) and immobilization of heavy metals released from CFT (copper flotation tailings) were investigated using strongly alkaline demolition waste (DW), collected from the urban renewal areas. Shake flask batch tests were conducted to assess the influence of time and different ratios of CFT/DW on the acidity and heavy metal release characteristics of the drainage water. During the tests, samples were collected from filtered leachates at regular intervals to monitor pH, SO42- and release of heavy metals. The results indicated that the pH increased from 2.21 (t=0) to 10.37 after 120 minutes of shaking in an orbital shaker. The highest SO42- release ([SO42-]=4558 mg L-1, t=0) was measured at 1:3 dose of CFT:DW application with 257 mg L-1 (pH=10.37) at the end of 120 minutes. The addition of DW almost completely reduced the release of heavy metals from CFT due to its high alkaline content. As a result, it was suggested that DW could effectively be used for the treatment of AMD and immobilization of heavy metals released from CFT.
Investigation of the role of CYP1A1 and CYP1B1 expressions in obesity susceptibility
Authors: POLAT Fatih , BULUŞ Hakan , KAYGIN Pınar , DİRİCAN Onur , GÜLER ŞİMŞEK Gülçin , SARIALTIN Sezen Yılmaz , GÜRBÜZ Fatıma Nurdan , YILMAZ Can , OĞUZTÜZÜN Serpil
Published: September 2022

Metabolik işleyiş, etkileri ve neden olduğu hastalıklar açısından daha multidisipliner bir bakış açısıyla anlaşılması gereken obezite, son yıllarda prevalansı ve insidansı artan hastalıklardan biri olarak görülmektedir. Bu hastalığın metabolik yolunda önemli enzim gruplarından biri olan sitokrom p450 (CYP1A1 ve CYP1B1) izozimlerinin rolünün ortaya konulması amaçlanmıştır. 2017-2019 yılları arasında Ankara Keçiören Eğitim ve Araştırma Hastanesi Genel Cerrahi Kliniği'nde obezite tanısı konulan ve bariatrik cerrahi, ksenobiyotik metabolizması uygulanan 152 hastaya immünohistokimya yöntemiyle CYP1A1 ve CYPB1 izoenzimlerinin ekspresyonu araştırılmıştır. CYP1A1 açısından elde edilen bulgular; 152 kişide CYP1A1 ve CYP1B1 immünohistokimya boyama düzeyleri incelenen dokuların %12.7'sinde CYP1A1 ekspresyonu gözlenmezken; %33.3, %32.5 ve %21.4'te zayıf bir CYP1A1 ifadesi gözlenmiştir. Dokuların %71.4'ünde CYP1B1 ekspresyonu görülmezken, dokuların %28.6'sında zayıf ekspresyon izlenmiştir. Hiçbir dokuda orta veya güçlü CYP1B1 ekspresyonu gözlenmemiştir. Kadın hastalardan alınan dokuların ortalama CYP1A1 ve CYP1B1 boyama seviyeleri erkek hastalardan daha yüksek bulunmuştur. Klinik verilerden diyabet parametresi (p
Prediction of Epidemic Disease Severity and the Relative Importance of the Factors for Epidemic Disease Using the Machine Learning Methods
Authors: KUTLU Hüseyin , ÇOLAK Cemil , DOĞAN Çağla Nur , TURĞUT Mehmet
Published: September 2022

Epidemic diseases have been seen frequently in recent years. Today’s, thanks to advanced database systems, it is possible to reach the clinical and demographic data of citizens. With the help of these data, machine learning algorithms can predict how severe (at home, hospital or intensive care unit) the disease will be experienced by patients in the risk group before the epidemic begins to spread. With these estimates, necessary precautions can be taken. In this study, during the COVID-19 epidemic, the data obtained from the Italian national drug database was used. COVID-19 severity and the features (Age, Diabetes, Hypertension etc.) that affect the severity was estimated using data mining (CRISP-DM method), machine learning approaches (Bagged Trees, XGBoost, Random Forest, SVM) and an algorithm solving the unbalanced class problem (SMOTE). According to the experimental findings, the Bagged Classification and Regression Trees (Bagged CART) yielded higher accuracy COVID-19 severity prediction results than other methods (83.7%). Age, cardiovascular diseases, hypertension, and diabetes were the four highest significant features based on the relative features calculated from the Bagged CART classifier. The proposed method can be implemented without losing time in different epidemic diseases that may arise in the future.
Comparison of traditional Zivzik pomegranate vinegar against commercial pomegranate vinegar: antioxidant activity and chemical composition
Authors: AYBEK Abdulkerim , AKKEMİK Ebru
Published: September 2022

The vinegar, which is known to be very beneficial for health, also changes its usage potential and chemical properties according to the raw material it is obtained from. In this study, Zivzik pomegranate Vinegar produced with the traditional methods from Zivzik pomegranate varieties was compared with commercial pomegranate vinegar in terms of physicochemical properties, total phenolic, total flavonoid, and total anthocyanin content, organic acid, sugar, and phenolic acid composition by HPLC, elemental analysis by ICP-OES and antioxidant properties. As a result of the study, Zivzik pomegranate vinegar was found to be more antioxidant than commercial vinegar. In both vinegar samples, K is the dominant element. Similarly, acetic acid is the dominant organic acid detected in both types of vinegar. While chlorogenic acid was the dominant phenolic compound in commercial pomegranate vinegar, it was determined that gallic acid was dominant in Zivzik pomegranate vinegar. As a result, while it was determined that the origin and variety of the raw material had a direct effect on the product quality obtained, it was concluded that the vinegar obtained by traditional methods was more beneficial in terms of health than commercial vinegar.
In silico Prediction and In vitro Antioxidant Activities of Two Jujube Fruits from Different Regions
Authors: UÇKAYA Fatih
Published: September 2022

Jujube is a fruit rich in antioxidant compounds and vitamin C. In this way, it can prevent cell damage by fighting free radicals. In the study, antioxidant activities, total phenolic and total flavonoid compound amounts of methanolic extracts of jujube fruits were determined. In addition, their biochemical compositions were determined using HPLC. Also, an in silico prediction study of the identified active ingredients was performed to evaluate antioxidant, antiradical, antibacterial, antifungal, anti-inflammatory, antimutagenic, and membrane integrity antagonist properties. For the determination of antioxidant capacity, ferric reducing power (FRAP) and cupric ion reducing capacity (CUPRAC), DPPH radical scavenging activity and β-carotene-linoleic acid assay were used. The amounts of total phenolic and the total flavonoid compounds of the extracts were determined as gallic acid equivalent (GAE) and as quercetin equivalent (QE). The methanolic extract of jujube collected from Antalya contains 580 μg GAE.mg-1 and 240 μg QE.mg-1, and the methanolic extract of jujube collected from Denizli contains 900 μg GA.mg-1 and 380 μg QE.mg-1. The IC50 values of Antalya and Denizli methanolic extracts according to the DPPH scavenging assay were 10.34 and 9.82, respectively. Gallic acid, catechin, caffeic acid, coumaric acid, ferulic acid and cinnamic acid were detected by HPLC. In addition, the in silico effects of these molecules were estimated with the PASS online prediction program. As a result, it was seen that Denizli jujube had a higher antioxidant effect than Antalya jujube.
Evaluations on the Use Potential of Some Woody Plants Naturally Growing in Elazig Flora in Landscape Architecture
Authors: ULUSAN Musa Denizhan , POLAT Rıdvan
Published: September 2022

In this study, the potential of use in the landscape area of some woody plants that naturally spread in the flora of Elazig was investigated. As a result of the researches, it was determined that 29 genera and 54 natural plant taxa belonging to 18 families in the region have potential landscape plant characteristics. Families with the most taxa; Rosaceae (19 taxa), Salicaceae (4 taxa), and Fagaceae (4 taxa). The genera with the most taxa are; Crataegus, Rosa and Quercus with 4 taxa each, followed by Acer, Tamarix and Sorbus with 3 taxa each.. As a result of the evaluation, the woody plants with landscape potential in the region are used for ornamentation, aesthetics, fence, ground cover, etc. It has been found that it can be used for many purposes.
A Generalized Thermoelastic Behaviour of Isotropic Hollow Cylinder
Authors: EKER Mehmet , YARIMPABUÇ Durmuş
Published: September 2022

In this study, the thermoelastic behavior of a thick-walled homogeneous cylinder based on Lord-Shulman theory is investigated. It is assumed that the inner and outer surfaces of the cylinder are traction-free, and the outer surface is insulated while the inner surface is subjected to a time-dependent internal temperature load. The governing equations in coupled form are solved with the pseudospectral Chebyshev method. The numerical approach is validated with benchmark results in the literature. The temperature, radial and tangential stress distributions are examined for three different moments to represent the time-varying effects of the applied instantaneous temperature load. The effect of the coupled term in Lord-Shulman theory for different high temperatures is examined and the difference between the coupled and uncoupled solution in different time periods is tabulated and the difference is highlighted.
Febre reumática – critérios de Jones revisados
Authors: Santos Maria Carolina dos
Published: September 2022

Febre reumática é uma complicação decorrente da infecção por estreptococo beta hemolítico do grupo A de Lancefield, que pode evoluir com comprometimento cardíaco com alta morbidade e mortalidade. Apesar de se observar um declínio de sua incidência, especialmente em países desenvolvidos, diante da variabilidade socioeconômica, ainda é problema de saúde pública em vários países em desenvolvimento, como o Brasil. Seu diagnóstico é feito através dos critérios de Jones, descritos inicialmente em 1944, que apresentaram modificações e sua última revisão ocorreu em 2015. Esta última revisão adquire importância pois passa a considerar a variabilidade geográfica de sua incidência, considerando populações de baixo risco e de moderado a alto risco para o desenvolvimento da febre reumática. Além disso, ressalta a importância do ecocardiograma como ferramenta para detecção de cardite subclínica. Além disso, estabelece critérios também para a definição dos casos de recorrências de febre reumática. Com critérios classificatórios da doença mais sensíveis e considerando a realidade de cada população, é possível um diagnóstico mais precoce e estabelecimento da terapêutica adequada, além de medidas de prevenção, evitando sua complicação mais grave, a doença cardíaca reumática.

Unitermos: Febre reumática. Criança. Cardite. Jones. Coreia.
Miopatias inflamatórias
Authors: Souza Jean Marcos de , Shinjo Samuel Katsuyuki
Published: September 2022

As miopatias inflamatórias idiopáticas (MII) ou miopatias autoimunes sistêmicas foram inicialmente descritas na década de 1970, quando eram classificadas como dermatomiosite ou polimiosite. Após quase 50 anos, diversas entidades clínicas novas foram definidas como a miosite por corpos de inclusão, a miopatia necrosante imunomediada, a síndrome antissintetase, as formas predominantemente cutâneas de dermatomiosite e as miopatias associadas a neoplasias ou outras colagenoses. Em 2017, a European League Against Rheumatism (EULAR) e o American College of Rheumatology (ACR) fizeram um esforço conjunto para criar os critérios classificatórios mais atuais para as MII e os critérios de resposta para guiar o seu tratamento. Esta revisão objetiva compilar os principais critérios classificatórios atuais para as MII e as principais métricas de seguimento clínico, bem como avaliar criticamente as qualidades e limitações de cada um deles.

Unitermos: Dermatomiosite. Miopatias inflamatórias. Miosites. Polimiosite. Síndrome antissintetase.
Critérios classificatórios para polimialgia reumática
Authors: Aguiar Mariana Freitas de
Published: September 2022

A polimialgia reumática (PMR) é uma doença inflamatória frequente em indivíduos com mais de 50 anos, e seu diagnóstico é baseado no quadro clínico de dor em cinturas (pélvica e escapular), acompanhado do aumento de provas inflamatórias e de achados radiológicos sugestivos, como a bursite subacromial e trocantérica. A lista de diagnósticos diferenciais para a PMR é grande e vários conjuntos de critérios para o diagnóstico da doença já foram desenvolvidos. Em 2012, o American College of Rheumatology (ACR) e a European League Against Rheumatism (EULAR) desenvolveram critérios provisórios de classificação para PMR, que apresentam sensibilidade 66-68% e especificidade 78-81%. Esses critérios funcionam a partir de um sistema de pontuação que se baseia na presença de manifestações clínicas típicas, na ausência de fator reumatoide e anti-CCP e, quando disponível, na presença de achados ultrassonográficos característicos. Apesar de serem úteis na prática clínica, esses critérios ainda precisam de validação prospectiva e sua acurácia para a diferenciação entre PMR e artrite reumatoide (AR) soronegativa do idoso é baixa.

Unitermos: Polimialgia reumática. Classificação. Diagnóstico diferencial. Ultrassonografia. Doença autoimune.
Implementation of Mean of Maximum on Cigarette Smoke Control in a Room
Authors:   Departement of Informatics, Institut Teknologi Nasional Bandung (ITENAS), Jl. PHH. Mustafa No. 23 Bandung, Indonesia 40124, NURHASANAH Youllia Indrawaty , BARMAWI Mira Musrini ,   Departement of Informatics, Institut Teknologi Nasional Bandung (ITENAS), Jl. PHH. Mustafa No. 23 Bandung, Indonesia 40124, PRAKARSA Ramsza ,   Departement of Informatics, Institut Teknologi Nasional Bandung (ITENAS), Jl. PHH. Mustafa No. 23 Bandung, Indonesia 40124
Published: September 2022

Home automation is an IoT technology that has the ability to communicate between devices. This technology requires a method for making the decision process. Fuzzy logic method is a solution to this problem. Fuzzy Logic is a method that functions to replicate and run human knowledge to control a system. In fuzzy logic algorithm, there are three main processes, which are fuzzification, inference, and defuzzification. Defuzzification process requires a method to obtain the value of crisp solutions. One of the many methods is Mean of Maximum (MoM). MoM is an algorithm that calculates the average of fuzzy conclusions or outputs that have the highest degree. In this research, we apply the MoM method in the defuzzification process to build a smoke emission control system in a room using an exhaust fan. Wemos D1 mini is used as a controller and processor in the system. And using telegram chatbot for communication media between users and the system. There are 27 rules in this system with 100% functionality. This research topic is very useful to keep the air clean and fresh in the room and avoid the dangers of cigarette smoke that can damage health.
Biocontrole de tombamento causado por Rhizoctonia solani em plântulas de feijão e soja com Clonostachys spp.
Authors:   , Almeida Ana Carolina de
Published: September 2022

Doenças causadas por fitopatógenos habitantes do solo são de difícil manejo, como é o caso de tombamentos causados por Rhizoctonia solani em culturas economicamente importantes no Brasil. A busca por tecnologias que possam contribuir com o manejo desta doença se torna de extrema importância e o biocontrole com microrganismos antagonistas é uma vertente a ser explorada. O objetivo deste trabalho foi avaliar diferentes espécies do gênero Clonostachys no biocontrole de tombamentos por R. solani em plantas de feijão e soja. Foram realizados dois bioensaios: em casa de vegetação com plantas de feijão e soja e em campo comercial de soja com histórico de infestação natural por fitopatógenos habitantes do solo. No primeiro, foi avaliado o efeito de dez isolados de nove espécies de Clonostachys, aplicados via tratamento de sementes (TS) ou via solo (AS), sobre a percentagem de emergência das plântulas em solo artificialmente infestado com R. solani. A incidência desses isolados nas raízes, sem e com desinfestação superficial, também foi avaliada. No segundo bioensaio, tratamentos compostos por duplas de isolados de três espécies de Clonostachys foram aplicados no sulco do plantio, de maneira individual ou combinada com um biofertilizante comercial; e a percentagem de emergência de plântulas e produtividade de grãos foram avaliadas. Em casa de vegetação, a aplicação de Clonostachys spp. via AS resultou em melhores índices de porcentagens de emergência das plântulas do que via TS. Dentre os dez isolados aplicados no solo, seis foram eficientes no biocontrole de tombamento em pré-emergência causada por R. solani no feijão, e oito isolados na soja, resultando em valores de emergência entre 40 e 80%, em contraste com percentagens de emergência entre 0 e 15% no controle com solo infestado com o fitopatógeno. O efeito de biocontrole de três isolados foi contrastante entre soja e feijão, evidenciando o efeito do hospedeiro na interação. A rizocompetência da maioria dos isolados não se relacionou com o biocontrole exercido por eles. No campo, a incidência natural de tombamentos foi pequena, provavelmente em decorrência do clima seco e quente no norte do Paraná no segundo semestre de 2020. Dessa forma, o efeito da aplicação de Clonostachys spp. no biocontrole não pôde ser avaliado. Conclui-se que, além de C. rosea, outras espécies do gênero são antagonistas úteis para o biocontrole de doenças causadas por R. solani e que, para alguns isolados, a planta hospedeira parece influenciar diretamente o efeito de controle. Palavras-chave: Tombamento. Rizocompetência. Antagonismo.