bluuebunny/crossref_metadata_2025 huggingface dataset:
Schoology, Changing A Negative Thinking Pattern About Use of Social Media
Authors: Rosy Brillian
Published: December 2018

Social media makes the user addicted, it seems to be a negative mindset when reviewing social media. The development of the era brings the development of technology and information, it has a considerable impact on behavior patterns and human thinking. At this time, children or teenagers to adulthood have a strong dependence on information. The need for technology and information is very varied, one easy way to access information is with social media. The use of social media without parental controls in children or adolescents, will have a negative impact. On the other hand also positively influence if its use becomes innovation in the learning process. There are several social media that are used as interactive learning media, now known as Learning Management System (LMS). LMS allows educators to create virtual classrooms as a means of interacting and accessing subject matter anytime and anywhere as long as there is an internet network. One of the social media (LMS) that can be used for learning is Schoology. This research is just a theory study which concludes that e-learning based learning media that is Schoology able to change the negative thinking that has been spread in the community will the use of social media.
The Development of SQL Language Skills in Data Definition and Data Manipulation Languages Using Exercises with Quizizz for Students' Learning Engagement
Authors: Amornchewin Ratchadaporn
Published: December 2018

The exercise is one of the educational activities that help students to understand and achieve their learning goals. Quizizz is a great online tool which helps students to check their knowledge and learning progress. In this paper, the researcher applied the SQL (Structured Query Language) skill in data definition language (DDL) and data manipulation language (DML) exercises and engaged the student’s learning by using Quizizz on students’ Introduction to Database course. The exercises and Quizizz were employed to an experimental group and a conventional teaching method was used for the control groups. The groups of students were of the heterogeneous level. Using the DDL and DML exercises, the students can review the knowledge repeatedly by doing exercises. In addition, the student can learn something from doing quizzes via Quizizz. The study on SQL exercises were conducted in order to improve students' achievement in DDL and DML. The purposes of this research were to 1) compare the students’ pre-test and post-test achievement using Quizizz and 2) investigate the students’ satisfaction while using SQL language skill exercises and Quizizz. The sample consisted of 34 students who enrolled in an Introduction to Database course in semester 1 of the academic year 2017. The students applied SQL language skill exercises when working on SQL assignment statement syntax. The students' pre-tests and post-tests were assessed. Percentage, mean and standard deviation, and average score (t-test) were used to analyze the data. The result showed that the students’ scores from the post-test was higher than the pre-test. There was a statistical significance at the level of 0.05. According to the result, it indicated that the students’ achievement was improved by the implementation. The students' satisfaction with the SQL language skill exercises and Quizizz was at a highest level (X = 4.58, S.D. = 0.54).
A qualidade de vida no trabalho como estratégia de gestão de pessoas: o caso de uma indústria gráfica de Santa Catarina
Authors: Silveira Machado Paulo Roberto , Perito Bárbara Zandomenico , Treptow Igor Ceratti , Drago Henrique Faverzani
Published: December 2018

A análise do nível da Qualidade de Vida no Trabalho (QVT) aliada à identificação dos principais fatores que a influenciam é uma das estratégias de gestão de pessoas nas indústrias. O presente estudo mediu a QVT dos colaboradores em uma indústria gráfica localizada no estado de Santa Catarina, Brasil. Para a coleta de dados, fez-se uso do questionário QWLQ-bref que alcançou 95% do total de colaboradores. Todos os questionários respondidos foram considerados válidos e utilizados na avaliação do resultado. A organização encontra-se entre os níveis médio e bom de QVT segundo a escala utilizada, visto que avaliação apresentou média global de 3,562 (71,24%). O domínio Físico/Saúde teve média de 3,601 (72,02%), o Psicológico de 3,465 (69,3%), o Pessoal de 3,724 (74,48%) e, por fim, o domínio Profissional de 3,459 (69,18%). O estudo mostrou que todos os domínios da QVT foram considerados satisfatórios pelos funcionários da empresa. O fator pessoal foi considerado como o fator de maior contentamento, enquanto o profissional o de maior descontentamento. A falta de investimento em qualificação foi apontada como o principal ponto de insatisfação. Por isso, sugere-se que os gestores da organização criem um plano de treinamento a fim de melhorar a satisfação dos seus colaboradores.
Análise do sistema de gestão de resíduos de equipamentos eletroeletrônicos da Alemanha e suas influências na logística reversa do município do Rio de Janeiro
Authors: Pacheco Genilson Jacinto , Pereira de Campos Tácio Mauro , Mattos Nascimento Daniel Luiz de
Published: December 2018

A contextualização do estudo discute as políticas e economias que envolvem a produção, consumo e descarte dos produtos eletroeletrônicos. O setor de produção de dispositivos eletroeletrônicos configura-se como o de maior crescimento dentro da indústria de manufatura nos países industrializados. O objetivo deste estudo é analisar e comparar os sistemas de gestão de resíduos de equipamentos eletroeletrônicos (REEE) da Alemanha e Brasil, para apontar melhorias no sistema de gestão do município do Rio de Janeiro, RJ, Brasil. O método utilizado foi elaborado em um cenário hipotético, com o propósito de focalizar a geração de REEE no município do Rio de Janeiro. Para isso, buscou-se dados via internet. Um dos principais resultados apontam que a Alemanha possui um sistema eficiente, por mapear todos os pontos de coleta de REEE por km² e por acompanhar os produtos colocados no mercado. O município do Rio de Janeiro prevê uma geração de 2.655.856.81 toneladas de REEE para o ano de 2018, cálculo obtido através do consumo e uso de domicílios. Considera-se o sistema de logística reversa como um instrumento destinado a garantir o fluxo de retorno dos resíduos ao ciclo produtivo, para viabilizar sua coleta e restituição ao setor empresarial (fabricantes, importadores), responsável por sua destinação final ambientalmente adequada. Esse estudo apresenta em uma revisão literária que consiste na identificação de dados combinados com um conjunto de regras para selecionar as peças relevantes da literatura e mapear o conteúdo da literatura extraindo informações.
impact of therapy dog visits on outpatient nurse welfare and job satisfaction
Authors: Clark Stephanie , Smidt Jessica , Bauer Brent
Published: December 2018

Interaction with a therapy dog can decrease blood pressure, heart rate, and improve heart rate variability; due to these responses, it suggests that human-animal interaction can alleviate the stress response. This study aims to observe if the effects of therapy dog visits could alleviate nursing burnout and increase work satisfaction in an outpatient setting. In addition, this study will observe at what visit frequency of therapy dog visits nurses benefited from most. This study is a two-part study, which also observed the salivary cortisol concentrations of the therapy dogs post therapy visit interaction. The study design was a randomized block design with five treatments over the course of four weeks: TRT A, two therapy dog visits a week; TRT B, one visit a week; TRT C, two visits; TRT D, one visit; and TRT E, no visits. Four out-patient nursing units were selected and asked to complete a demographic survey, the Pet Attitude Scale-Modified, and Lexington Attachment to Pet Scale. Pre- and post-treatments, participants completed the Human Services Survey, Nursing Workplace Satisfaction Questionnaire, Nursing Work Index (Revised), and a visual analog scale. TRT A was able to significantly increase the feeling of happiness. In addition TRT B, a therapy dog visit once a week, was able to significantly reduce self-reported responses of depression and improve emotional wellbeing. Consequently, TRT E, control/no therapy dog visits, had the least amount of improvement in the nursing units’ visual analog scale. This study supports the hypothesis that therapy dog visits can help alleviate stress, frustration, feeling drained, and the overwhelming sensation that can come from working in the nursing field.
Urban Adaptation to Climate Change: geographers and wicked problems
Authors: Kirby Andrew
Published: December 2018

This paper explores the importance of adaptation to climate change impacts in urban areas. The complexity of existing and likely impacts poses unique challenges to all aspects of society, from state to polity and economy. These in turn pose methodological challenges to academic practice, demanding the integration of macro and micro perspectives and pure and applied research. The paper argues that geographers can make significant contributions to this scholarship.
Comparison of Intravenous Lidocaine and Dexmedetomidine Infusion for Prevention of Postoperative Catheter-Related Bladder Discomfort: A Randomized Controlled Trial
Authors: Li Shuying , Li Hui , Ni Juan , Ma Yushan
Published: December 2018

Background: Catheter-related bladder discomfort (CRBD) frequently occurs during recovery in patients who undergo intra-operative urinary catheterization distress. We conducted this study to compare the effect of intravenous lidocaine and dexmedetomidine infusion for preventing CRBD.
Methods: 120 patients undergoing elective open abdominal hysterectomy and hysteromyoma requiring urinary bladder catheterization were randomly allocated into three groups of 40 each. Group L received a 2 mg/kg lidocaine bolus followed by infusion of 1.5 mg/kg/h; Group D received a 0.5 mg/kg dexmedetomidine bolus followed by infusion of 0.4 mg/kg/h; Group C received a bolus and infusion of normal saline of equivalent volume. The incidence and different severity (mild, moderate, and severe) of CRBD were assessed on arrival in the postanaesthesia care unit at 0, 1, 2, and 6 h postoperatively.
Results: The incidence of CRBD was significantly lower in Group L and Group D compared with Group C at 0, 1, and 2 h. However, there was no significant difference among the three groups regarding the different severity of CRBD at all time points. The requirement of rescue tramadol for CRBD was lower in group L and group D than in group C. The incidence of sedation was significantly higher in Group D compared to Group L and Group C, though no difference in other adverse effects was observed.
Conclusions: Intravenous lidocaine and dexmedetomidine infusion reduced the incidence of CRBD as well as the additional tramadol requirement for CRBD, but had no effect on the different severity of CRBD.
Clinical Features and Surgical Outcomes of Pediatric Ocular Trauma in Southwest of China
Authors: He Yan , Nian Songwen , Wu Nan , Wang Yi , Yu Tao , Liu Yong
Published: December 2018

Background: Ocular trauma is one of the major threats of monocular blindness in children. The purpose of the study was to investigate the epidemiology, clinical characteristics and surgical outcomes of pediatric ocular trauma in southwest of China.
Methods: The medical records of all patients with ocular trauma under 12 years old receiving three-port pars plana vitrectomy (PPV) in Southwest Eye Hospital from January 2007 to December 2017 were retrospectively analyzed in this study. Data records included age, gender, cause, type and time of injury, initial and final visual acuity (VA), type and times of operation.
Results: This study included 122 eyes of 122 pediatric patients over a 11-year period. The mean age was 6.6 ± 3.2 years with a male-to-female ratio of 4.3:1. There were 100 (82%) open globe injuries (OGI) and 22 (18%) closed globe injuries. Of the open globe injuries, penetrating injury caused by sharp metal objects accounted for the highest percentage (70%). PPV could significantly improve VA in children with ocular trauma (P ˂ 0.01). In addition, the successful rate of PPV was not related with the age (P = 0.23) but significantly associated with intraocular tamponade (P < 0.05).
Conclusions: The most common predisposing factor of pediatric ocular trauma in southwest of China was sharp metal objects resulting in penetrating injury. In our study, gas tamponade for vitrectomy had the highest successful rate, followed by balanced salt solution (BSS) and silicone oil. Unlike the age and injury classification, the preoperative VA was a solid prognostic indicator of postoperative vision.
Comparative analysis of optical aberrations, anatomical and optical parameters of the cornea in glaucoma surgery
Authors: Neroev V. V. , Aliev A. A-G. , Nurudinov M. M.
Published: December 2018

Purpose. A combined comparative study of the impact of antiglaucomatous surgeries on the anatomical and optical parameters of the cornea.

Materials and methods. The study involved 38 patients (38 eyes) aged 43 to 75 with primary open-angle glaucoma (POAG), which were divided into 2 groups. Patients of group I (15 eyes) underwent classical deep sclerectomy (DSE), while those of group II (23 eyes), had non-penetrating deep sclerectomy (NDSE). All patients underwent a comprehensive examination before and after surgery, including precision visometry, corneal topography, OCT pachymetry.Results. Group I revealed a significant change in the parameters on the 3rd day after the surgery; in particular, the average value of corneal astigmatism increased from -0.93 D to -3.62 D, the curvature radius of the cornea in the vertical meridian increased from 7.56 ± 0.07 mm to 8.34 ± 0.04 mm, the thickness of the central cornea changed from 514.5 ± 0.04 μm to 520.6 ± 0.06 μm. In group II, the corneal astigmatism increased from -0.86 D to -2.75 D, and the curvature radius of the cornea in the vertical meridian changed from 7.72 ± 0.05 mm to 8.12 ± 0.03 mm, the central thickness of the cornea increased from 515.4 ± 0.04 to 516.8 ± 0.12 μm.

Conclusion. The degree of surgically induced changes of anatomic and optical parameters of the cornea in POAG patients depended on the amount of intervention: NDSE has a lesser effect on these parameters than classical DSE.
A symmetric hypocorrection of myopia by FemtoLASIK in patients with presbyopia
Authors: Khodzhabekyan N. V. , Khandzhyan A. T. , Tarutta E. P.
Published: December 2018

Purpose: to evaluate the results of symmetric binocular hypocorrection of myopia with FemtoLasik surgery in patients with presbyopia of various age groups.

Material and methods. 33 patients (66 eyes) with myopic refraction, aged 36 to 50, were operated by FemtoLasik. The intended Femto Flap thickness was 100 μm. The patients were divided into three groups depending on age; group 1 included 16 patients (32 eyes) aged 39–44, group 2 had 12 patients (24 eyes) aged 45–50, and group 3 (controls) was composed of 5 patients (10 eyes) of pre-presbyopic age (36–38 years).

Results. The symmetric binocular hypocorrection proved efficient in 35 % of cases in the group 1 and 50 % of cases in group 2. In the control group the intended and obtained values coincided in all 100 % of cases.

Conclusion. A possible cause of the discrepancy between the intended and the obtained hypocorrection effect may be a reduced corneal hydration of patients older than 39 years.
Herkes İçin Mobil Öğrenme: Mobil Uygulamaların Evrensel Tasarım İlkelerine Göre İncelenmesi
Authors: Şenel Selma , Şenel Hüseyin , Günaydın Serpil
Published: December 2018

Günümüzde, mobil öğrenme giderek yaygınlaşmaktadır. Bireyin yaşı,
kültürü, engeli, deneyimleri ne olursa olsun mobil ortamlardan
faydalanabilmektedirler. Kullanıcı kitlesindeki çeşitlilik nedeniyle mobil
uygulamaların tüm bireylerin kullanabileceği şekilde tasarlanması önemlidir.
Evrensel tasarım; her türlü ürün ve süreci daha kapsayıcı kılmayı amaçlayan bir
yaklaşımdır. Bu araştırmada, mobil öğrenme süreçlerinde evrensel tasarımının
önemine dikkat çekmek amaçlanmıştır. Bu çerçevede, öğrenme için evrensel
tasarım ilkeleri temel alınarak, üç boyut ve 45 maddeden oluşan bir kontrol
listesi geliştirilmiştir. Tüm dünyada yaygın olarak kullanılan ve yabancı dil
eğitimi sunan 26 mobil uygulama kontrol listesine göre incelenmiştir. Araştırma
sonucunda uygulamaların, özellikle “içeriğin sunumu”nda yetersiz oldukları
gözlenmiştir. Uygulamaların “kullanım ve etkileşim seçenekleri” ve “motivasyonu
arttırma” boyutlarında ise orta yeterlikte oldukları gözlenmiştir. Sonuç
olarak, dünya çapında kullanılan uygulamalarda dahi farklı özelliklerdeki
bireylerin kullanımı açısından eksikliklerinin olduğu belirtilebilir.
Bulgulardan yola çıkarak, mobil uygulamaların tasarımında evrensel tasarım
ilkelerinde işaret edilen özel gereksinimli bireylerin de göz önünde
bulundurulmasına gayret gösterilmesi önerilmektedir.
A numerical investigation on vibration analysis of fiber reinforced and truncated conical hollow shells with different fiber orientations
Authors: BULUT Mehmet
Published: December 2018

Truncated conical shells have been extensively used in a wide range of engineering applications dueto their special geometric shapes, and their vibration properties have been interested by many researchers in recentyears. In this study, vibration analysis of truncated conical hollow shells constructed from the fiber reinforcedcarbon/epoxy composites was investigated for different fiber orientation angles ([0o/90o], [15o/-75o], [30o/-60o], and[45o/-45o]). Finite element analysis (FEA) was performed by using ABAQUS software for prediction of naturalfrequencies and mode shapes within the extended frequency range. Natural frequency values were determinedfor constant semi-vertex angle of the conical structure (45o), and boundary conditions of clamped-clamped(C-C), simply supported-simply supported (S-S) and clamped-free (C-F). It is concluded that natural frequency hasbeen significantly affected by boundary conditions while it has been little effected by fiber orientation angle thoseeffecting on mode shapes associated with natural frequencies.
Kapsaisin ve Tarımda Kullanımı
Authors: ARIN Levent
Published: December 2018

Kapsaisin Capsicum türlerinde büyük oranda meyvede bulunan ana acılık bileşenidir. Acılık kalıtsal birözelliktir, ancak kültürel uygulamalar ve çevre faktörlerinden de etkilenir. Sadece baharat ve lezzet verici olarakdeğil aynı zamanda farmakolojik ve fizyolojik etkileri nedeniyle medikal ve tedavi amaçlı kullanılmaktadır.Kapsaisinden özellikle organik tarımda böcek ve akar gibi zararlılar için uzaklaştırıcı özelliğinin yanında bazıpatojenik mantar ve bakterilere karşıda yararlanılmaktadır. Ancak, metabolizması, taşınımı ve bitki gelişimi üzerineetkisiyle ilgili bilgiler sınırlıdır. Bu makalede günümüze kadar kullanıla gelen kapsaisin ile ilgili kısa bilgi verilmişve bazı araştırma sonuçları sunulmuştur.
Effect Of Astaxanthin On Rat Brains Against Oxidative Stress Induced By Cadmium:Biochemical, Histopathological Evaluation
Authors: AKKOYUN Hürrem Turan , BENGU Aydin Sukru , ULUCAN Aykut , BAYRAMOGLU AKKOYUN Mahire , EKİN Suat , TEMEL Yusuf , ÇİFTÇİ Mehmet
Published: December 2018

Aim of this study is to evaluate protective impact of Astaxanthin (AST) on rats with experimentalbrain injury induced with Cadmium (Cd). 32 male Wistar albino rats were divided into four groups as Control,Cadmium, Astaxanthin (AST), Cadmium (Cd)+Astaxanthin (AST). Rat brain tissues were obtained at the endof 30th day. Malondialdehyde (MDA), glutathione (GSH) levels and superoxide dismutase (SOD) enzymeactivities were measured in brain homogenates and histopathological examination was performed. MDA levelswere improvement in cadmium administered group (p<0.01) as well as Cd+AST administered group (p<0.05)compared to control group. In addition a substantial reduction Cd+AST group was observed compared to cadmiumadministered group (p<0.01). GSH level shows a decrease in Cd and Cd+AST groups compared to control (p<0.05).SOD enzyme activity was found significantly lower in Cd and Cd+AST groups compared to control (p<0.01). Inaddition, increase of SOD in Cd+AST group compared to cadmium group was also found significant (p<0.05).Histopathological findings in the cerebral cortex and hippocampus were different between groups. In the controland AST administered groups, normal histological structure was observed in the brain, while severe lesions wereseen in the Cd administered group and in the Cd+AST group only mild degenerative lesions were observed.As a result, elevated MDA level due to Cd administration was attenuated with AST administration. Decreased GSHlevel and SOD enzyme activity due to Cd administration was increased with AST administration. In addition, ASTadministration decreased histopathological lesions. Consequently, it is thought that AST may be used for protectionagainst brain oxidative damage due to Cd.
2-(3-Hidroksi-4-metoksibenzilidenamino)-5-merkapto-1,3,4- tiyadiazol Bileşiğinin Sentezi, Moleküler Yapısı, Spektral ve Elektronik Özelliklerinin İncelenmesi
Authors: BEYTUR Murat , AKYILDIRIM Onur , MANAP Sevda , YÜKSEK Haydar
Published: December 2018

Bu çalışmada, 2-(3-hidroksi-4-metoksibenzilidenamino)-5-merkapto-1,3,4-tiyadiazol molekülünün geometrik parametreleri (bağ uzunlukları ve bağ açıları), titreşim frekansları, 1H-NMR ve 13C-NMR spektral değerleri ve doğrusal olmayan optik (NLO) özellikleri üzerine teorik ve deneysel bir çalışma gerçekleştirilmiştir. Öncelikle, 2-(3-hidroksi-4-metoksibenzilidenamino)-5-merkapto-1,3,4-tiyadiazol B3LYP/HF 6-311G+(d,p) temel setleri kullanılarak optimize edilmiştir. GIAO yöntemine göre 1H-NMR ve 13C-NMR kimyasal kayma değerleri optimize edilmiş yapıdan başlanarak DMSO fazında Gaussian G09W program paketi kullanılarak hesaplanmıştır. Molekülün titreşim dalga sayıları HF ve B3LYP standardı kullanılarak yoğunluk fonksiyonu teorilerine göre 6-311G+(d,p) temel seti vasıtasıyla incelenmiştir. İlgili bileşiğin FT-IR (100-4000 cm-1) titreşim frekansları kaydedilmiştir. B3LYP ve HF yöntemlerinde elde edilen titreşim frekansları deneysel değerler ile mukayese edilmiş ve deneysel değerlere en yakın sonuçların B3LYP verilerinin olduğu gözlemlenmiştir. Ek olarak, sentezlenmiş yeni bileşiğin HOMO ve LUMO enerjileri, moleküler elektrostatik potansiyeli, elektron ilgisi, iyonlaşma potansiyeli, moleküler yumuşaklık, moleküler sertlik, elektronegatiflik, dipol momentleri ve toplam enerjileri gibi elektronik özellikleri aynı set ve yöntemler kullanılarak hesaplanmıştır.
Identification of chemical components from the Rhizomes of Acorus calamus L. with gas chromatography-tandem mass spectrometry (GC-MS\MS)
Authors: ATALAR Mehmet Nuri , TÜRKAN Fikret
Published: December 2018

In current work our main objective was to search the chemical components of volatiles in AcorusCalamus L. was identified by gas chromatography-tandem mass spectrometry (GC-MS\MS) combined withheadspace (HS) technique. The technique is a very valuable in terms of the extraction yield, sample work uptime, and profiling analysis. According to the our study data, about 78 chemical components were detected fromthe rhizomes of Acorus calamus L. by headspace method. The major components are as follows: 75.8% asarone,79% benzen, 25,8 % trans-β-Ocimene, 20,5% Isocalamendiol, 20,1 % Methyleugenol, 22,6% 3-Carene 17.40%ß-asarone and 17.1% α-Pinene. In terms of the characteristics of the components contained in this plant and studiesshow that Acorus calamus could be a potential source of novel antibacterial, antioxidant ve anticancer agent.
A Importância de Repensar as Práticas de Leitura na Formação Inicial da Criança
Authors: Da Rosa Salquini Cláudia , Rodrigues Marinéa Figueira
Published: December 2018

O presente estudo investigou a importância da leitura na formação inicial da criança e sua relevância para a inserção sociocultural como condição essencial para o pleno exercício da cidadania. Para tanto, realizou- se uma pesquisa de cunho bibliográfica baseada em renomados autores no assunto. A finalidade foi ressaltar a importância dessa temática como condição essencial para a formação de leitores proficientes. Enfatiza o valor do ato de ler, o incentivo da família e da escola.  Portanto, conclui- se que se faz necessário que a família e escola estabeleçam uma parceria, para que juntos alcancem um padrão de excelência nos serviços prestados à criança, obtendo assim sucesso escolar.
Análise retrospectiva da incidência de neoplasias em Vassouras/RJ
Authors: Ramos Alex Pereira , Da Cunha Gonçalves Sebastião Jorge
Published: December 2018

As elevadas taxas de  prevalência e incidência têm sido alvos de debate, tendo como objetivo o planejamento de estratégias de saúde que visem a diminuição desses índices. Através do SISPACTO, estabeleceu-se que deveria haver a diminuição de 2% do indicador de saúde (indicador 30a) quando fosse comparado com o ano anterior. Em Vassouras, entre 2007 até 2016, essa meta só foi alcançada três vezes, sendo que em apenas uma oportunidade houve queda da incidência. O objetivo desse trabalho é analisar retrospectivamente o número de casos de neoplasias no município de Vassouras/RJ, evidenciando políticas de saúde do município para controle dessas doenças, comparando, também, à incidência estadual. A incidência de neoplasias malignas em Vassouras no período de 2007 a 2016 foi de 492 casos por 100.000 habitantes, um valor considerado alto, ainda mais quando em comparação com a incidência das doenças em todo o estado do Rio de Janeiro (214 por 100.000, no período de 2008 a 2016). Em Vassouras/RJ, a política de controle vem funcionado de modo interdisciplinar, respeitando a realidade da saúde nacional no aspecto condizente à importância do foco na saúde da mulher e do homem. . Não há preconização, além das estabelecidas pelo Ministério da Saúde e INCA, para as neoplasias visualizadas no sexo masculino, categoria historicamente mais difícil de se abordar nas estratégias de saúde. Percebe-se através dessa análise, que a evolução do câncer em Vassouras se deu de forma ímpar, necessitando de adaptações para sua epidemiologia para que haja um melhor controle nos fatores causais.
Tumor de krukenberg metastático sem diagnóstico prévio de tumor primário: relato de caso
Authors: Albergaria Roberta Maria Rola , Alvim Júlia Pereira , Salles Lucas Oliveira , Guerra Maria Júlia Campos , Maia Lucineide Martins de Oliveira , Queiroz Aline Trovão
Published: December 2018

O tumor de Krukenberg (TK) é uma metástase neoplásica ovariana incomum, representa 1-2% dos cânceres incidentes no ovário, nos quais o estômago é a localização primária mais habitual. O objetivo do estudo foi relatar um caso de uma paciente de 42 anos, com TK metastático diagnosticado após laparotomia de emergência, relacionado a uma neoplasia gástrica sem diagnóstico prévio. A média de idade encontrada em pacientes com TK é 45 anos, sendo que a maioria dos casos relatados trata-se de TK bilateral. Os sintomas podem ser inespecíficos, com diagnósticos incidentais intraopertórios, ou relacionados ao envolvimento ovarianos, com dor e distensão abdominal e irregularidade menstrual. Comumente os pacientes podem ser assintomáticos, tendo manifestações clínicas somente muito tardiamente. A expressão de recptores de hormônios sexuais no TK ainda é indeterminada. Em relação ao prognóstico, a metastasectomia promove uma maior sobrevida aos pacientes, enquanto a cirurgia citorredutora revelou efeitos benéficos em relação a sobrevida, porém pode associar-se ao aumento da morbimortalidade e recorrências. Ainda não há consenso definido na literatura sobre o tratamento ideal, embora haja avanços nos estudos. O TK é um diagnóstico raro, acomente mais mulheres na pré-menopausa e tem um prognóstico ruim. A primeira recomendação para melhor sobrevida da paciente é a ressecção da lesão metastásica, seguida de terapia sistêmica paliativa.
Ruptura De Bexiga Após Trauma Abdominal Leve: Relato De Caso
Authors: Mattos Vinícius André Santos , Queiroz Aline Trovão , Trajano Eduardo Tavares Lima , Passos Márcio Terra
Published: December 2018

A ruptura da bexiga pode ocorrer decorrente de trauma direto (ruptura intraperitoneal), ou por fragmentos de ossos pélvicos decorrentes de fratura (ruptura extraperitoneal). A bexiga vazia apenas será lesada se houver um esmagamento ou ferimento penetrante, já que nessa condição ela fica protegida pelos ossos pélvicos. O método de imagem padrão ouro para o diagnóstico é a cistografia, entretanto ela vem sendo substituída pela cistotomografia devido à capacidade desta de melhor avaliar lesões associadas. A conduta terapêutica na ruptura intraperitoneal de bexiga é a cirurgia, por meio do desbridamento das áreas desvitalizadas, rafia e lavagem da cavidade abdominal com solução salina a 0,9%. O objetivo do artigo é relatar um caso de ruptura de bexiga intraperitoneal em um paciente hígido após um trauma abdominal leve. Os casos já relatados posteriormente a um trauma abdominal leve ocorreram, principalmente, em pacientes que já possuíam certa fragilidade da parede vesical, etilistas crônicos ou portadores de retenção urinária. Conclui-se que, independente da intensidade do trauma é importante considerar a ruptura da bexiga e uma rápida abordagem cirúrgica, evitando complicações de um diagnóstico prorrogado.
A Educação Ambiental como forma de prevenção de Crime Ambiental envolvendo uma serpente Boa constrictor no município de Eng. Paulo de Frontin - RJ: Estudo de caso.
Authors: Furusawa Guilherme Pinheiro
Published: December 2018

A presente nota refere-se a um estudo de caso, envolvendo crime ambiental com uma espécie nativa de serpente Boa constrictor, ocorrido no município de Engenheiro Paulo de Frontin - RJ e a Educação Ambiental como forma de prevenção nesse tipo de drama.
Temporary Solubilizing Tags Method for the Chemical Synthesis of Hydrophobic Proteins
Authors: Zhao Dong-Dong , Fan Xiao-Wen , Hao He , Zhang Hong-Li , Guo Ye
Published: December 2018

Hydrophobic proteins, as one of the cellular protein classifications, play an essential function in maintaining the normal life cycle of living cells. Researches on the structure and function of hydrophobic proteins promote the exploration of the causes of major diseases, and development of new therapeutic agents for disease treatment. However, the poor water solubility of hydrophobic proteins creates problems for their preparation, separation, characterization and functional studies. The temporary solubilizing tags are considered a practical strategy to effectively solve the poor water solubility problem of hydrophobic proteins. This strategy can significantly improve the water solubility of hydrophobic peptides/proteins, making them like water-soluble peptides/proteins easy to be purified, characterized. More importantly, the temporary solubilizing tags can be removed after protein synthesis, so thus the structure and function of the hydrophobic proteins are not affected. At present, temporary solubilizing tags have been successfully used to prepare many important hydrophobic proteins such as membrane proteins, lipoproteins and chaperones. In this review, we summarize the recent researches and applications of temporary solubilizing tags.
Zinc Sulfamate Catalyzed Efficient Selective Synthesis of Benzimidazole Derivatives under Ambient Conditions
Authors: Mathapati Sushil R. , Jadhav Arvind H. , Swami Mantosh B. , Dawle Jairaj K.
Published: December 2018

Zinc sulfamate (Zn(NH2SO3)2 is a derivative of sulfamic acid (H3NSO3) which possesses
“Lewis acidity” and finds well suited in a number of catalytic applications. The present paper describes
an efficient, eco-friendly, and clean synthesis of 2-substituted benzimidazole derivatives by reacting
diverse o-phenylenediamine with various substituted aromatic aldehydes using a catalytic amount of
zinc sulfamate in ethanol at ambient temperature. As a result, 10 mol.% of Zinc sulfamate catalyst
showed 92% of respective product yield with 100% conversion using short reaction period in ethanol.
Meanwhile, effect of reaction parameters, such as amount of catalyst, different solvents, and reaction
temperature on reaction product, was also studied. In addition, in the optimized reaction condition
various substituted biological important benzimidazoles derivatives were prepared by using optimized
reaction condition in good to efficient yield. In addition, possible reaction mechanism in the presence
of zinc sulfamate for the preparation of benzimidazole derivative was sketched and discussed. The present
green approach showed significances with faster reaction rate with inexpensive catalyst, which
showed excellent and clean yield of benzimidazole in mild reaction condition with easy work-up procedure.
Cryoballoon Ablation for the Treatment of Atrial Fibrillation: A Meta-analysis
Authors: Patel Nirav , Patel Krunalkumar , Shenoy Abhishek , Baker William L. , Makaryus Amgad N. , El-Sherif Nabil
Published: December 2018

Background:

Ablation therapy is the treatment of choice in antiarrhythmic drugrefractory
atrial fibrillation (AF). It is performed by either cryoballoon ablation (CBA) or radiofrequency
ablation. CBA is gaining popularity due to simplicity with similar efficacy and complication
rate compared with RFA. In this meta-analysis, we compare the recurrence rate of AF and the
complications from CBA versus RFA for the treatment of AF.

Methods:

We systematically searched PubMed for the articles that compared the outcome of interest.
The primary outcome was to compare the recurrence rate of AF between CBA and RFA. We
also included subgroup analysis with complications of pericardial effusion, phrenic nerve palsy and
cerebral microemboli following ablation therapy.

Results:

A total of 24 studies with 3527 patients met our predefined inclusion criteria. Recurrence
of AF after CBA or RFA was similar in both groups (RR: 0.84; 95% CI: 0.65, 1.07; I2=48%, Cochrane
p=0.16). In subgroup analysis, heterogeneity was less in paroxysmal AF (I2=0%, Cochrane
p=0.46) compared to mixed AF (I2=72%, Cochrane p=0.003). Procedure and fluoroscopy time was
less by 26.37 and 5.94 minutes respectively in CBA compared to RFA. Complications, pericardial
effusion, and silent cerebral microemboli, were not different between the two groups, however,
phrenic nerve palsy was exclusively present only in CBA group.

Conclusion:

This study confirms that the effectiveness of CBA is similar to RFA in the treatment
of AF with the added advantages of shorter procedure and fluoroscopy times.
Service Discovery and Selection in Internet of Things - A Review
Authors: Kashyap Neeti , Kumari Achanta C. , Chhikara Rita
Published: December 2018

The Internet of Things (IoT) is a novel technology that has opened doors to the new level
of interaction between the things. This has resulted in an enhancement in the quality of life and
optimized use of various resources. IoT uses various technologies related to networking, sensing,
databases and artificial intelligence to enhance the lifestyle and makes business processes simpler. In
the IoT based systems, the number of devices contributing to a particular application is very large,
spreading to a large geographical area at various locations. The device can be considered as a
resource used by a service in the application layer. IoT service is the most important entity. The
real-world things generate data by perceiving the environment in large quantity and store it in the
distributed databases or cloud databases. This manuscript analytically and statistically categorizes
and analyze the current research techniques on the service discovery and selection in the IoT,
published between 2010 and 2018. It finds that the discovery among a huge number of services
requires fast, scalable and dynamic service discovery mechanism over the Internet. Once the services
are discovered, the next step is to select the most appropriate service. This paper includes a
comprehensive analysis of the discovery and selection of services in IoT. A patent related to service
and discovery have been also discussed which would be beneficial in identifying the research gap to
make the system more efficient.
How to Kill Another Shark: A First Inside Look at a Potential Hunting Strategy of the Galapagos Shark
Authors: Ritter Erich K. , Munoz Alberto
Published: December 2018

Background:

Close-up videos of sharks foraging on other live sharks are rare, especially when it comes to footage of the entire duration of an event.

Objective:

Our goal was to present an in-depth analysis involving a Galapagos shark,Carcharhinus galapagensis, foraging on a whitetip reef shark,Triaenodon obesus.

Method:

A frame by frame video examination was used to highlight the different aspects of this bout.

Results:

Several behavioral characteristics, including the somewhat cryptic approach, the extensive shaking once the Galapagos shark had the whitetip reef shark between its jaws, and devouring tail-first, stand out in this event.

Conclusion:

The entire act appeared very smooth, indicating that this bout, or at least parts thereof, may represent a common hunting strategy for Galapagos sharks.
Factors Impacting the Use of Terminology to Convey Diagnostic Certainty in Radiology Reports
Authors: Lacson Ronilda , Babatunde Victor , Shinagare Atul , Khorasani Ramin
Published: December 2018

Background:

Variable use of phrases expressing diagnostic uncertainty can lead to ambiguous radiology reports, a concern for information processing.

Objective:

This study aimed to quantify the usage of phrases conveying diagnostic certainty for abdominal imaging findings and assess factors that impact use of phrases with “good agreement” between radiologists and referring providers.

Methods:

This retrospective, Institutional Review Board-Approved study included all diagnostic reports generated by the Abdominal Radiology Division at an academic medical center July-September 2016. We assessed the use of 16 diagnostic certainty phrases using information retrieval from the Impression section of radiology reports. Phrases with good provider agreement for conveying the level of certainty are defined as “good agreement” phrases - including “diagnostic of”, “represents” and “unlikely.” We assessed the impact of imaging modality, trainee contribution to report generation, and individual radiologists.

Results:

In 5,598 radiology reports, 2,071 (37%) contained diagnostic certainty phrases, 119 (6%) of which were “good agreement” phrases. There was a significant difference between how frequently “good agreement” phrases were used in Magnetic Resonance Imaging (MRI), Computed Tomography (CT) and X-ray reports (p=0.0003). There was a significant variation among attending radiologists on the use of “good agreement” phrases (p<0.0019). There was no difference in the use of “good agreement” phrases in reports generated by attending radiologists alone compared to reports with trainees.

Conclusion:

Although phrases to convey diagnostic certainty were commonly used in radiology reports, the use of phrases with a good agreement was uncommon. Standardizing terminology to convey diagnostic certainty may reduce ambiguity in radiology reports and generate more accurate information processing tools.
Analysis of the Emission Reduction through Performance Improvement of Intersection and Network nearby Using Micro Simulation Program
Authors: Arliansyah Joni , Bawono Ragil Tri
Published: December 2018

Introduction:

Palembang as one of the big cities in Indonesia is the capital city of South Sumatra Province. Congestion occurs at the main intersections of the city, one of which is Simpang Patal Pusri which has a long queue and delays in peak hour of 655 m and 490 seconds. The action performed to improve traffic performance and reduce the air pollution at this intersection was the underpass construction. This study discussed the importance of constructing an underpass together with improving geometric design and traffic management at the nearest intersections to obtain optimal results in addressing traffic problems and emissions reductions.

Methods:

To analyze the performance of traffic intersection and its network, Vissim simulation micro program and Program Moves were used to find out the emission values ​​of Total Carbon, NOx and PM10 of the analyzed handling scenarios.

Results:

The results showed that the construction of an underpass accompanied by the improved geometric design and traffic management at the nearest intersection produced better intersection performance and emission reductions when compared to only underpass construction, where the average V/C decreased from 0.87 to 0.77, the average queue decreased from 290.3 m to 190.57 m, and the average delay decreased from 106.34 seconds to 85.07 seconds. The values ​​of Total Carbon, NOx and PM10 also decreased significantly on all the roads in the study area.

Conclusion:

Based on the analysis, a scenario of the underpass construction is combined with geometric improvement and traffic management at the intersections which provides the best traffic performance and emissions reduction at either the intersections or road segments of the road network being studied.
Thermal Structure‐Induced Biochemical Parameters Stratification in a Subtropical Dam Reservoir
Authors: Mao Yufeng , He Qiang , Li Hong , Su Xiaoxuan , Ai Hainan
Published: December 2018

Although stratification in deep lakes is well‐discussed, few studies pay attention to thermal structure as well as its influences on stratification of biochemical parameters in subtropical lakes in mountainous cities. Here, we studied the depth profile of temperature and biochemical parameters in Longjing Lake, a subtropical reservoir in a mountainous city. Thermal stratification became strong during summer. Biochemical parameters were strongly associated with thermal structure. Stratification started at 2∼6 m depth with a substantial decrease in dissolved oxygen, biochemical oxygen demand (BOD5), chlorophyll a, and pH, corresponding to an increase in total nitrogen, ammonium (), nitrite (), total inorganic nitrogen (TIN), total phosphorus, and soluble reactive phosphorus (SRP) with depth; the majority of biochemical parameters showed slight variations from 12 m downward. Our results indicated the stratification of Longjing Lake was stronger and more stable than the stratification of tropical and temperate lakes in lowland cities.
Reduction of Imidacloprid by Sponge Iron and Identification of its Degradation Products
Authors: Zhou Xiaohui , Tian Ying , Liu Xiao , Huang Liping , Wen Yang
Published: December 2018

In this study, imidacloprid was degraded by sponge iron in aqueous solution via chemical reduction. The effects of initial pH, reaction time, and operating model were investigated. Lower of pH was advantageous to the reduction degradation reaction. The influence of agitation was investigated in terms of reaction kinetics and degradation yield. Imidacloprid degradation with agitation showed first‐order reaction kinetics with a reaction rate of 0.0235 min−1, and degradation without agitation possessed two distinctive kinetics regimes; a rapid reduction in the initial stage and a slower process until removal was complete. Both stages of the degradation showed first‐order reaction kinetics with reaction rates of 0.0122 min−1 and 0.0030 min−1, respectively. Transformation products were identified using high‐performance liquid chromatography‐mass spectrometry (HPLC‐MS). HPLC‐MS exhibited nine fragment ions at m/z 97, 155.9, 174.9, 196.9, 211.1, 269.9, 266.1, 279, and 301.1. Finally, a degradation pathway of imidacloprid was proposed.
Kajian keamanan pangan dan tingkat prevalensi cemaran bakterisusu di Sentra Pengembangan Sapi Perah Cilongok
Authors: Syamsi Afduha Nurus , Astuti Triana Yuni , Widodo Hermawan Setyo
Published: December 2018

The experiment was aimed to assess the food securitythrough physical properties, chemical composition and prevalence rate of milk bacterial contamination in Cilongok dairy cattle development center. Surveys and observations were conducted to obtain data on milking and milk processing applied by farmer and to obtain data on physical properties, chemical composition, and milk total bacterial count. The materialswere used farmer and milk samples taken 20 liters in total from 13 Andini Lestari 1 farmers and 7 Andini Lestrari 2 farmers. Data from the laboratory were analyzed descriptively based on the Standard Nasional Indonesia (SNI): 3141.1.2011, "t" test was used to distinguish milk quality based on physical properties, chemical composition and total bactery from both groups. The results showed that physical properties, chemical composition, and total bactery from both groups were not significantly different (P> 0.05). The conclusion of the research stated that Cilongok Dairy Cattle Development Center produces milk that is suitable for consumption based on physical and chemical composition in accordance with SNI standard: No.3141.1.2011 that showed low prevalence of bacterial contamination.
Review : Kejadian mastitis dan kaitannya dengan vitamin dan Trace Mineral Cu, Zn, Se
Authors: Yanuartono Yanuartono - , Nururrozi Alfarisa , Indarjulianto Soedarmanto , Purnamaningsih Hary , Haribowo Nurman
Published: December 2018

Mastitis means inflammation of the udder and is a common disease among dairy cows worldwide. It is subdivided into clinical mastitis and subclinical mastitis, both influence milk quality and quantity, and mastitis is therefore of major economic concern for the farmer. The incidence rate of mastitis varies between herds and depends on the exposure to pathogens, environmental and management factors and the immune status of the cow. Mastitis is associated with release of free radicals, increased total oxidant capacity and decreased total antioxidants capacity in milk. Vitamin C, E, , α tocopherol, A, β-karoten and trace mineral (Cu, Zn, and Se) feeding, as an antioxidant, in dairy cows have shown appreciable protective effects by reducing the incidence of mastitis.The purpose of this review is to discuss the role of Vitamins C, E, α tocopherol, A, β-carotene, Cu, Zn, and Se in the incidence of mastitis.
An economic evaluation of a computer-tailored e-learning program to promote smoking cessation counseling guideline adherence among practice nurses (Preprint)
Authors: de Ruijter Dennis , Hoving Ciska , Evers Silvia , Hudales Raesita , de Vries Hein , Smit Eline
Published: December 2018

BACKGROUND

To date, no evidence is available about the cost-effectiveness of digital support programs to improve smoking cessation care by healthcare professionals in primary care.

OBJECTIVE

To conduct an economic evaluation of a tailored e-learning program, which successfully improved practice nurses’ smoking cessation guideline adherence, from a societal perspective.

METHODS

The economic evaluation was embedded in a randomized controlled trial, in which 269 practice nurses recruited 388 smoking patients. Cost-effectiveness was assessed using guideline adherence as effect measure on practice nurse level, and continued smoking abstinence on patient level. Cost-utility was assessed on patient level, using patients’ Quality Adjusted Life Years (QALYs) as effect measure.

RESULTS

The e-learning program was likely to be cost-effective on practice nurse level, as adherence to an additional guideline step cost €1,586. On patient level, cost-effectiveness was slightly likely after six months (cost per additional quitter: €7,126), but not after twelve months. The cost-utility analysis revealed slight cost-effectiveness (cost per QALY gained: €18,431) on patient level.

CONCLUSIONS

Providing practice nurses with a tailored e-learning program is cost-effective to improve their smoking cessation counseling. Cost-effectiveness on patient level was not found, which may result from smoking relapse. Widespread implementation of the e-learning program can improve the quality of smoking cessation care in general practice. Strategies to prevent patients’ smoking relapse should be further explored to improve patients’ long-term abstinence.

CLINICALTRIAL

Dutch Trial Register NTR4436; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=4436. (Archived by WebCite at http://www.webcitation.org/6zJQuSRq0)