bluuebunny/crossref_metadata_2025 huggingface dataset:
Antibodies against medically relevant arthropod-borne viruses in the ubiquitous African rodent Mastomys natalensis
Authors: De Kesel Wim , Vanden Broecke Bram , Borremans Benny , Fourchault Léa , Willems Elisabeth , Ceulemans Ann , Sabuni Christopher , Massawe Apia , Makundi Rhodes H. , Leirs Herwig , Peeters Martine , Verheyen Erik , Gryseels Sophie , Mariën Joachim , Ariën Kevin K.
Published: September 2024

Over the past decades, the number of arthropod-borne virus (arbovirus) outbreaks has increased worldwide. Knowledge regarding the sylvatic cycle (i.e., non-human hosts/environment) of arboviruses is limited, particularly in Africa, and the main hosts for virus maintenance are unknown. Previous studies have shown the presence of antibodies against certain arboviruses (i.e., chikungunya-, dengue-, and Zika virus) in African non-human primates and bats. We hypothesize that small mammals, specifically rodents, may function as amplifying hosts in anthropogenic environments. The detection of RNA of most arboviruses is complicated by the viruses’ short viremic period within their hosts. An alternative to determine arbovirus hosts is by detecting antibodies, which can persist several months. Therefore, we developed a high-throughput multiplex immunoassay to detect antibodies against 15 medically relevant arboviruses. We used this assay to assess approximately 1,300 blood samples of the multimammate mouse,Mastomys natalensisfrom Tanzania. In 24% of the samples, we detected antibodies against at least one of the tested arboviruses, with high seroprevalences of antibodies reacting against dengue virus serotype one (7.6%) and two (8.4%), and chikungunya virus (6%). Seroprevalence was higher in females and increased with age, which could be explained by inherent immunity and behavioral differences between sexes, and the increased chance of exposure to an arbovirus with age. We evaluated whether antibodies against multiple arboviruses co-occur more often than randomly and found that this may be true for some members of theFlaviviridaeandTogaviridae. In conclusion, the development of an assay against a wide diversity of medically relevant arboviruses enabled the analysis of a large sample collection of one of the most abundant African small mammals. Our findings highlight thatMastomys natalensisis involved in the transmission cycle of multiple arboviruses and provide a solid foundation to better understand the role of this ubiquitous rodent in arbovirus outbreaks.
Coordination of parental performance is breeding phase-dependent in the Dovekie (Alle alle), a pelagic Arctic seabird
Authors: Grissot Antoine , Altmeyer Lauraleen , Devogel Marion , Zalewska Emilia , Borrel Clara , Kidawa Dorota , Jakubas Dariusz , Wojczulanis-Jakubas Katarzyna
Published: September 2024

Currently, parental care is becoming increasingly perceived as male and female cooperation, instead of being primarily shaped by sexual conflict. Most studies examining cooperating performance consider coordination of parental activities, and doing so focuses on a short time-window including only one stage of breeding (i.e., incubation or chick rearing period). Here, we considered the cooperation of breeding partners, investigating the coordination of parental care in a long-lived seabird species with long and extensive biparental care, the Dovekie (or Little Auk), Alle alle, and looked at the issue throughout the breeding season. Previous studies on this species revealed coordinated chick provisioning, but parental coordination during incubation remains unstudied. Using video recordings collected over the course of two breeding seasons, we tested whether coordination was subject to small-scale changes within each stage and whether there was a relationship between coordination levels across the two stages. We found that the level of parental coordination is overall high and increases during the incubation period but decreases through the chick rearing phases. There were some inter-annual differences in the coordination level both at the incubation and chick rearing stages. We also found some dependency between the coordination during the incubation and chick rearing periods. All these results suggest that coordination is not a fixed behavior but breeding-phase dependent. The present study thus provides insights into how parental care and parents’ cooperation is shaped by brood needs and conditions. It also highlights a relationship between coordination levels during chick rearing and incubation periods, suggesting some extent of temporal dependence in coordination of parental performance within the breeding season.
A biophysical minimal model to investigate age-related changes in CA1 pyramidal cell electrical activity
Authors: McKiernan Erin C. , Herrera-Valdez Marco A. , Marrone Diano F.
Published: September 2024

Aging is a physiological process that is still poorly understood, especially with respect to effects on the brain. There are open questions about aging that are difficult to answer with an experimental approach. Underlying challenges include the difficulty of recording in vivo single cell and network activity simultaneously with submillisecond resolution, and brain compensatory mechanisms triggered by genetic, pharmacologic, or behavioral manipulations. Mathematical modeling can help address some of these questions by allowing us to fix parameters that cannot be controlled experimentally and investigate neural activity under different conditions. We present a biophysical minimal model of CA1 pyramidal cells (PCs) based on general expressions for transmembrane ion transport derived from thermodynamical principles. The model allows directly varying the contribution of ion channels by changing their number. By analyzing the dynamics of the model, we find parameter ranges that reproduce the variability in electrical activity seen in PCs. In addition, increasing the L-type Ca2+ channel expression in the model reproduces age-related changes in electrical activity that are qualitatively and quantitatively similar to those observed in PCs from aged animals. We also make predictions about age-related changes in PC bursting activity that, to our knowledge, have not been reported previously. We conclude that the model’s biophysical nature, flexibility, and computational simplicity make it a potentially powerful complement to experimental studies of aging.
Exploring emotional well-being, spiritual, religious and personal beliefs and telomere length in chronic pain patients—A pilot study with cross-sectional design
Authors: Rönne-Petersén Linn , Niemi Maria , Walach Harald , Lavebratt Catharina , Yang Liu L. , Gerdle Björn , Ghafouri Bijar , Falkenberg Torkel
Published: September 2024

Living with chronic pain is associated with substantial suffering and high societal costs. Patient reported outcomes (PROM’s) and cellular ageing should be considered in pain management. The aim of this study was to explore correlations of PROM’s and cellular ageing (telomere length [TL] and telomerase activity [TA]) amongst patients with chronic non-malignant pain. This was an explorative pilot study with cross-sectional design and recruitment was done at two pain rehabilitation facilities in Sweden, with inpatient setting/integrative care and outpatient setting/multimodal care, respectively. Eighty-four patients were enrolled by referral to pain rehabilitation in Sweden. The main outcome measures collected after admission in addition to TL and TA were the following PROMs: Numerical Rating Scale (NRS), Chronic Pain Acceptance Questionnaire (CPAQ), Hospital Anxiety and Depression Scale (HADS), Five Facets Mindfulness Questionnaire (FFMQ), WHO Quality of Life–Spiritual, Religious and Personal Beliefs (WHOQoL-SRPB) and EuroQol 5 Dimensions (EQ-5D). All the PROM’s showed evidence of poor overall health status among the participants. TL correlated negatively with HADS score (r = -.219, p = .047) and positively with WHOQoL-SRPB (r = .224, p = .052). TL did not correlate with any of the pain measures. TA correlated positively with pain spread (r = .222, p = .049). A mediation of the direct effect of spiritual well-being on TL by anxiety and depression could be shown (b = 0.008; p = .045). The correlations between TL and SRPB and anxiety and depression suggest some importance of emotional and SRPB dimensions in pain management, with implications for cellular aging, which may warrant further study.

Trial registration: ClinicalTrials.gov Identifier: NCT02459639.
Food expenditure, income, and mental health: Outcomes from the UK Household Longitudinal Survey
Authors: Waqas Muhammad , Iqbal Syka , Stewart-Knox Barbara J.
Published: September 2024

The incidence of mental health problems is increasing in the United Kingdom and may be associated with lower dietary quality. Food expenditure is a marker of food insecurity with potential implications for mental health. This analysis considers data collected as part of the United Kingdom Household Longitudinal Survey (UKHLS), also known as ‘Understanding Society’ (2009–2021) (N = 388,944) to determine the extent to which food expenditure within and outside the household, is associated with mental health, whilst controlling for demographic factors. Mental health was measured using the General Health Questionnaire (GHQ-12) for which responses were on a 4-point scale and reverse-scored so that a higher score represented more favourable mental health. Household food expenditure and food expenditure outside the home were the outcomes. Controlling for socioeconomic and demographic factors, fixed-effects models indicated that better mental health was associated with greater household food expenditure and with greater food expenditure outside the home and that this association persisted post-lockdown. Among those on lower incomes better mental health was associated with lower food expenditure. When people who identified as white and non-white were modelled separately, better mental health was associated with lower food expenditure within and beyond the household only in those who identified as white. These findings imply that the mental health of people residing in the UK, particularly those on lower incomes and those who identify as white, may benefit from spending less of the household budget on food. In achieving United Nations General Assembly (2012) Sustainable Development Goals related to poverty, hunger and in promoting mental health, policies are needed to render food more affordable and to reduce other aspects of expenditure that impact upon food budgeting.
Mathematical modeling and numerical simulation of supercritical processing of drug nanoparticles optimization for green processing: AI analysis
Authors: Aljohani Khalid
Published: September 2024

In recent decades, unfavorable solubility of novel therapeutic agents is considered as an important challenge in pharmaceutical industry. Supercritical carbon dioxide (SCCO2) is known as a green, cost-effective, high-performance, and promising solvent to develop the low solubility of drugs with the aim of enhancing their therapeutic effects. The prominent objective of this study is to improve and modify disparate predictive models through artificial intelligence (AI) to estimate the optimized value of the Oxaprozin solubility in SCCO2 system. In this paper, three different models were selected to develop models on a solubility dataset. Pressure (bar) and temperature (K) are the two inputs for each vector, and each vector has one output (solubility). Selected models include NU-SVM, Linear-SVM, and Decision Tree (DT). Models were optimized through hyper-parameters and assessed applying standard metrics. Considering R-squared metric, NU-SVM, Linear-SVM, and DT have scores of 0.994, 0.854, and 0.950, respectively. Also, they have RMSE error rates of 3.0982E-05, 1.5024E-04, and 1.1680E-04, respectively. Based on the evaluations made, NU-SVM was considered as the most precise method, and optimal values can be summarized as (T = 336.05 K, P = 400.0 bar, solubility = 0.00127) employing this model. Fig 4
Acute blood loss in mice forces differentiation of both CD45-positive and CD45-negative erythroid cells and leads to a decreased CCL3 chemokine production by bone marrow erythroid cells
Authors: Nazarov Kirill , Perik-Zavodskii Roman , Perik-Zavodskaia Olga , Alrhmoun Saleh , Volynets Marina , Shevchenko Julia , Sennikov Sergey
Published: September 2024

Hemorrhage, a condition that accompanies most physical trauma cases, remains an important field of study, a field that has been extensively studied in the immunological context for myeloid and lymphoid cells, but not as much for erythroid cells. In this study, we studied the immunological response of murine erythroid cells to acute blood loss using flow cytometry, NanoString immune transcriptome profiling, and BioPlex cytokine secretome profiling. We observed that acute blood loss forces the differentiation of murine erythroid cells in both bone marrow and spleen and that there was an up-regulation of several immune response genes, in particular pathogen-associated molecular pattern sensing gene Clec5a in post-acute blood loss murine bone marrow erythroid cells. We believe that the up-regulation of the Clec5a gene in bone marrow erythroid cells could help bone marrow erythroid cells detect and eliminate pathogens with the help of reactive oxygen species and antimicrobial proteins calprotectin and cathelicidin, the genes of which (S100a8, S100a9, and Camp) dominate the expression in bone marrow erythroid cells of mice.
Less experienced observers assess piglet castration-induced acute pain differently than experienced observers: A pilot study
Authors: da Silva Gustavo Venâncio , Lopez-Soriano Magdiel , Pairis-Garcia Monique Danielle , Trindade Pedro Henrique Esteves
Published: September 2024

Behavioral pain scales have been helpful for standardized swine pain assessment. However, it is still unknown if observers’ experience influences the scale score. We conducted a pilot study to investigate how three different levels of swine experience influenced how observers scored castration pain in piglets using Unesp-Botucatu Pig Composite Acute Pain Scale (UPAPS). We used a database from UPAPS scores from pigs undergoing surgical castration in a previous study. Scores were attributed by six observers with Little to no experience (n = 2), Some experience (n = 2) and Extensive experience (n = 2). Reliability was estimated using the intraclass correlation coefficient, agreement was investigated by Bland-Altman analysis, predictive capacity was estimated using the area under the curve (AUC), and statistical differences were tested using a regression model. We found that intra-experience levels reliability were satisfactory (Little to no: 0.72, Some: 0.81, Extensive: 0.84), but inter-experience reliability was lower (0.42). Little to no experience observers had poor agreement with other observers, with a bias toward underscoring UPAPS (bias of 0.94 vs. Some, 1.17 vs. Extensive). Predictive capacity was similar between all observers (AUC, Little to no: 71.94%, Some: 76.10%, Extensive: 79.09%, p > 0.05). Regression model confirmed underscoring of Little to no experience observers (mean ± standard error; Little to no: 1.09 ± 0.14; Some: 2.02 ± 0.23; Extensive: 2.25 ± 0.22; p < 0.05). We concluded that minimal experience, as Some experience observers have in the swine industry, is sufficient for them to score UPAPS in a similar way than more experienced observers. The present pilot study supports the enhancement and implementation of UPAPS on farm and laboratory settings by minimally qualified observers, improving swine welfare in the short and long term.
Combination therapy synergism prediction for virus treatment using machine learning models
Authors: Majidifar Shayan , Zabihian Arash , Hooshmand Mohsen
Published: September 2024

Combining different drugs synergistically is an essential aspect of developing effective treatments. Although there is a plethora of research on computational prediction for new combination therapies, there is limited to no research on combination therapies in the treatment of viral diseases. This paper proposes AI-based models for predicting novel antiviral combinations to treat virus diseases synergistically. To do this, we assembled a comprehensive dataset comprising information on viral strains, drug compounds, and their known interactions. As far as we know, this is the first dataset and learning model on combination therapy for viruses. Our proposal includes using a random forest model, an SVM model, and a deep model to train viral combination therapy. The machine learning models showed the highest performance, and the predicted values were validated by a t-test, indicating the effectiveness of the proposed methods. One of the predicted combinations of acyclovir and ribavirin has been experimentally confirmed to have a synergistic antiviral effect against herpes simplex type-1 virus, as described in the literature.
Characterization of bacterial communities associated with seabed sediments in offshore and nearshore sites to improve Microbiologically Influenced Corrosion mitigation on marine infrastructures
Authors: Ghezzi Daniele , Mangiaterra Gianmarco , Scardino Arianna , Fehervari Mauro , Magnani Mauro , Citterio Barbara , Frangipani Emanuela
Published: September 2024

Microbiologically Influenced Corrosion (MIC) is one of the main threats for marine infrastructures, leading to severe safety and environmental risks associated with structural failures and/or leakages of dangerous fluids, together with potential huge economic losses and reputational damage for the involved parts. For a safe design and a proper installation of infrastructure systems in contact with the seabed, a deep knowledge of the site-specific microbial community of the sediments should be beneficial. Therefore, in addition to the simple detection or the sole quantification of Sulphate-Reducing Bacteria (SRB), the whole characterization of the microbial members involved in MIC phenomena is desirable. In this study, 16S rRNA-based comparison between bacterial communities thriving in offshore and nearshore marine sediments was performed, with a focus on the main bacterial groups putatively responsible for MIC. The nearshore sediments were significantly enriched in bacterial members associated with human and organic compounds contamination belonging to the Bacteroidota, Desulfobacterota, and Firmicutes phyla, while the offshore sediments hosted Alphaproteobacteria, Nitrospinota, and Nitrospirota members, representative of a low anthropogenic impact. Quantitative PCR targeting the dsrA gene and detailed community analyses revealed that the nearshore sediments were significantly enriched in SRB mainly affiliated to the Desulfobulbus and Desulfosarcina genera potentially involved in biocorrosion, compared to the offshore ones. These results suggest that the bacterial community associated with the high concentration of organic compounds derived by an elevated anthropogenic impact is likely to favour MIC. Such observations highlight the importance of microbiological investigations as prevention strategy against MIC processes, aiming both at characterizing sites for the establishment of new infrastructures and at monitoring those already installed.
A partial deletion within the meiosis-specific sporulation domain SPO22 of Tex11 is not associated with infertility in mice
Authors: Ghieh Farah , Passet Bruno , Poumerol Elodie , Castille Johan , Calvel Pierre , Vilotte Jean-Luc , Sellem Eli , Jouneau Luc , Mambu-Mambueni Hendrick , Garchon Henri-Jean , Pailhoux Eric , Vialard François , Mandon-Pépin Béatrice
Published: September 2024

Azoospermia (the complete absence of spermatozoa in the semen) is a common cause of male infertility. The etiology of azoospermia is poorly understood. Whole-genome analysis of azoospermic men has identified a number of candidate genes, such as the X-linked testis-expressed 11 (TEX11) gene. Using a comparative genomic hybridization array, an exonic deletion (exons 10–12) of TEX11 had previously been identified in two non-apparent azoospermic patients. However, the putative impact of this genetic alteration on spermatogenesis and the azoospermia phenotype had not been validated functionally. We therefore used a CRISPR/Cas9 system to generate a mouse model (Tex11Ex9-11del/Y) with a partial TEX11 deletion that mimicked the human mutation. Surprisingly, the mutant male Tex11Ex9-11del/Y mice were fertile. The sperm concentration, motility, and morphology were normal. Similarly, the mutant mouse line’s testis transcriptome was normal, and the expression of spermatogenesis genes was not altered. These results suggest that the mouse equivalent of the partial deletion observed in two infertile male with azoospermia has no impact on spermatogenesis or fertility in mice, at least of a FVB/N genetic background and until 10 months of age. Mimicking a human mutation does not necessarily lead to the same human phenotype in mice, highlighting significant differences species.
Bottled water, tap water and household-treated tap water–insight into potential health risks and aesthetic concerns in drinking water
Authors: Bear Samantha E. , Waxenberg Talya , Schroeder Charles R. , Goddard Jessica J.
Published: September 2024

Understanding drinking water quality at the point-of-use across a range of consumer options is essential for designing effective public health interventions in the face of deteriorating source waters and complex contaminant mixtures. This is especially pressing as the popularity of tap water alternatives like bottled water and household treatment increases, yet this data is largely missing from the academic literature and policy discussions. This study presents one of the first evaluations of water quality comparing three common consumer drinking water options in the nine county San Francisco Bay Area with a survey of 100 analytes in 100 bottled water samples, 603 tap water samples, and 111 samples of household-treated tap water. Analytes measured included general water quality characteristics, metals, other inorganics, volatile organic compounds (including disinfection byproducts), and three microbial indicator species in bottled water only. Samples were evaluated to assess potential taste, odor, and color issues, as well as potential health risks by calculating cumulative toxicity quotients to reflect the additive toxicity of chemical mixtures. All three drinking water options had potential health risks, primarily driven by the presence of trihalomethanes (contributing from 76.7 to 94.5% of the total cumulative toxicity across the three drinking water options). While tap water had the highest potential toxicity among the three drinking water options, results suggest that household-scale treatment may reduce the potential for aesthetic issues and health risks of tap water.
Reimagining reality through decolonial and quantum lenses in abstract animation
Authors: Chavez Mark , Conradi Ina
Published: September 2024

This article will discuss how a decolonial multidisciplinary approach leverages Indigenous design elements to articulate and convey the intricate principles of quantum mechanics, exploring the rich intersection of quantum mechanics and abstract animated imagery. In doing so, conventional perceptions of reality are challenged and reimagined. We posit that the confluence of these diverse disciplines facilitates a novel and profound understanding of the universe, interpreting symbolically through an artistic lens secrets that suggest the metaphysical.
Using data as materiality
Authors: Peters Maybelle
Published: September 2024

In this article, I discuss how an analysis of creating human avatars has been a catalyst for developing a critically engaged use of motion capture data. I demonstrate how my moving image practice responds to motion capture technology processes. This development of a methodological framework has been used to rethink how I construct virtual animated figures. Each stage of making considers data as a piece of interpretive information to create animation. I have examined three phases of production. They are integral to the fabrication, construction and mediation of digital humans found in motion capture libraries. These interconnected processes dominate how motion is captured and used creatively. By utilizing the means of production, my research investigates how cultural hegemonic practices facilitate notions of universalism. I discuss how a model of standardized visual identities is biased towards staging white male normativity as a prototypical human. This observation informs my challenge to find an expansive form of producing digital figures in motion. I have considered how the logic of categories utilized by motion capture libraries promotes a seemingly natural arrangement of racialized differences. Whilst this form of normative coding creates homogeneous bodies, I examine how my own racialized Black identity informs my methods for disrupting the reproduction of this system. My response to the hierarchical structure of colonial systems of order is investigated using theories of the human. These concepts are rooted in Black studies and are deployed as decolonial perspectives. My use of computational data offers an expansive and generative understanding of human movement abstracted from the body. This decolonial response moves away from considering representation in terms of external visual markers of my African Caribbean heritage. Instead, my technical processes navigate how dominant modes of creating virtual characters can rethink ideas of the human within a historical, political and sociocultural context.
The Development of the Two-Tier Diagnostic Test Instrument with Google Form to Measure Student Misconceptions on Energy and Energy Forms
Authors: Pratiwi Ika Thalia , Viyanti  , Permadi Dimas
Published: September 2024

This study develops a two-tier diagnostic test instrument with Google Forms- to measure student misconceptions about energy and energy forms. The development research used the 4-D model with 4 stages: (1) define; (2) design; (3) develop; and (4) disseminate. The researchers validated the product to evaluate the construct, material, and language aspects. Expert validation results declared the two-tier diagnostic test instrument very valid at 87.7%. The researchers tested the two-tier diagnostic test instrument with Google form to measure student misconceptions on 30 students and then analyzed using the Rasch model with the assistance of Ministep 5.6.2 software. Based on the results of the Rasch analysis, 20 valid items were obtained. The questions on the two-tier diagnostic test instrument to measure student misconceptions were reliable, with a Cronbach alpha value of 0.66, categorized as adequate. The final product of the developed instrument met the standards of instrument validity and reliability.
Meta Analisis: Efektivitas Cognitive Behavioral Therapy untuk Insomnia
Authors: Rahma Lili , Yudiarso Ananta
Published: September 2024

Insomnia cases in Indonesia and worldwide as well have increased every year. Based on data found cases of insomnia increased during the COVID-19 pandemic. The intervention that is widely used in dealing with insomnia is by using cognitive behavioral therapy (CBT) intervention techniques. Several previous studies have conducted research related to CBT for insomnia (CBT-I). This research was conducted to see the magnitude of the effect size arising from CBT on insomnia and to increase statistical insight using meta-analysis approach of hedge's g. The study used 14 research journal articles discussing cognitive behavioral therapy and insomnia which involved total of 7085 respondents. The results of this study found that cognitive behavioral therapy was quite effective in reducing insomnia (g=-0.57). 
 
Kasus insomnia di Indonesia maupun di dunia mengalami peningkatan setiap tahunnya. Berdasarkan data yang ditemukkan kasus insomnia bertambah selama masa pandemi COVID-19 berlangsung. Intervensi yang banyak digunakan dalam menangani insomnia adalah dengan menggunakan teknik intervensi cognitive behavioral therapy (CBT). Beberapa penelitian terdahulu sudah melakukan penelitian berkaitan dengan CBT untuk insomnia (CBT-I). Penelitian ini dilakukan untuk melihat besaran effect sizeyang ditimbulkan dari CBT terhadap insomnia serta meningkatkan wawasan statistik dengan menggunakan meta-analisis. Pada penelitian ini menggunakan metode meta-analisis yang mana dalam analisisnya menggunakan aplikasi JAMOVI versi 2.2.5 dana melihat effect size menggunakan nilai hedge’s g. penelitian menggunakan 14 artikel jurnal penelitian yang membahas mengenai cognitive behavioral therapy dan insomnia yang mana melibatkan sebanyak 7085 responden. Hasil dari penelitian ini menemukkan bahwa cognitive behavioral therapy cukup efektif  dalam menurunkan insomnia (g=-0.57).
Perilaku Mencari Perhatian pada Remaja Akhir dengan Latar Belakang Keluarga Broken Home
Authors: Syahrani Alifia , Palila Sara
Published: September 2024

Tantangan yang berbeda dihadapi oleh remaja yang hidup dalam keluarga bermasalah yang sering disebut dengan keluarga broken home. Satu di antaranya adalah bagaimana mereka cenderung lebih banyak mencari perhatian dari orang sekitar. Tujuan penelitian ini adalah ingin melihat bagaimana gambaran perilaku mencari perhatian pada remaja yang berada dalam keluarga broken home. Penelitian ini menggunakan metode kualitatif dengan pendekatan fenomenologi. Data dikumpulkan melalui teknik wawancara dan dokumentasi terhadap tiga orang informan dengan kondisi keluarga broken home yang berbeda. Penelitian memberikan hasil bahwa perilaku mencari perhatian pada informan beragam, baik yang bentuknya negatif seperti menyakiti diri maupun positif yang berwujud pada dorongan belajar dan berprestasi yang tinggi. Hal yang mungkin berpengaruh adalah bentuk broken home yang dialami, pengaruh lingkungan sekitar, maupun kondisi internal dari remaja itu sendiri. Hasil penelitian ini diharapkan dapat menjadi dasar untuk mengembangkan rancangan modul intervensi yang dapat membantu remaja yang hidup dari keluarga broken mengelola dorongan mencari perhatian agar termanifestasi dalam perilaku yang lebih adaptif. 

 
Different challenges are faced by teenagers who live in problematic families which are often called broken homes. One of them is how they tend to seek more attention from the people around them. The aim of this research is to explore the attention-seeking behavior of teenagers in broken home. This research uses a qualitative method with a phenomenological approach. Data was collected through interview and documentation techniques from three informants with different broken home family conditions. The research showed that attention-seeking behavior of the informants varied, both in negative forms such as self–harm and positive ones in the form of encouragement for learning and high achievement. Factors that may have an influence are the form of broken home experienced, surrounding environment, and internal condition of the teenager theirself. It is hoped that the result of this research can be the basis for developing intervention designs that can help adolescents living from broken families manage the urge to seek attention thus it manifests in more adaptive behavior.
PENGANTAR REDAKSI
Authors: Redaksi Pengantar
Published: September 2024

Jurnal Sosiologi Reflektif volume 14 nomor 1, Oktober 2019 ini mengkaji permasalahan sosial yang kompleks dalam perspektif sosiologis. kajian ditulis dalam edisi ini mencakup: harmoni kehidupan keberagamaan, perubahan sosial dalam konteks keagamaan, gerakan sosial keagamaan serta gerakan-gerakan sosial masyarakat.
Digitizing Tolerance Practices as an Effort to Prevent Religious Conflict in Aceh through New Media
Authors: Husna Fathayatul , Zulkarnain Annisa
Published: September 2024

This article opens an academic discourse on tolerance campaign strategies as a new form of conflict resolution in Aceh. LABPSA is an institution that accommodates young people to campaign for tolerance, inclusiveness, gender equality, and other social issues. All participants who join LABPSA carry out various tolerance campaign strategies. These strategies focus on how young people optimize social media to campaign for issues of tolerance. The data collection process is carried out by studies based on virtual ethnographic methods and online documentation. This step was carried out by looking at the landscape of religious conflicts that occurred in Indonesia, especially in Aceh province. What is the role of the Aceh government in carrying out conflict resolution to resolve religious conflicts in Aceh? What form of active participation did young people take when voicing the issue of tolerance through LABPSA? The results of this study are that the presence of young people under the LABPSA institution is a new way to voice acts of tolerance and resolve religious conflicts in Aceh. The various activities carried out are a form of dissatisfaction with the Aceh government's response to the issue of intolerance. On the other hand, the presence of young people in LABPSA is also part of helping the Aceh government resolve conflicts in Aceh, especially religious conflicts, and eradicating issues of intolerance.
Perception of Parenting Practices in Pesantren Al-Ittifaqiyah Through the Eyes of Santri
Authors: Jahidin Asep , Yusuf Albana  , Idan Ramdani  , Sindy Shofa Dermawati
Published: September 2024

The Islamic boarding school (pesantren) caregiver of Santri is a widely ignored issue in the management of Pesantren as an Islamic educational institution that requires Santri to live and participate in various daily activities. This study examines how the thoughts and ideas of pesantren relate to the parenting of santri based on the phenomenon in Pesantren Al-Ittifaqiyyah, Indralaya, Ogan Ilir, South Sumatra. By analyzing the conceptual problems of adolescent Santri's perspectives on pesantren parenting and communication built into the implementation of parenting in the pesantren, a parenting institution, Data collection was carried out through in-depth interviews with adolescent Santri living in Pesantren, caregivers in Pesantren, and leadership elements in Pesantren. Document searches and studies were also conducted, including reviewing archives, physical devices, conducting field observations, and participant observations. The results showed that the santri's views on parenting and its forms of communication in pesantren have a variety of dimensions in the parenting process in pesantren, including six dimensions, namely warmth, rejection, rules, conflict, freedom, support, and coercion, as well as the typical dimensions of pesantren, namely religion, independence, and administration. Communication is the key to establishing a parenting pattern that includes these dimensions when carrying out parenting in the pesantren environment.
Assessing the Impact of News Reporting Regarding the Mount Semeru Eruption
Authors: Gama Betty , Yoto Widodo Yoto , Widarwati Nunun Tri , Kusumawati Henny Sri Kusumawati
Published: September 2024

Communication has an important role in supporting the process of education and learning. To make the learning material well transformed for santri (students), an appropriate and effective communication strategy is needed. Thus, this study analyzes communication strategies in empowering entrepreneurship at Pesantren Asshiddiqiyah 2, Tangerang. This is a qualitative study and uses a case study method. Its data was collected by case studies, in-depth interviews and literature studies. Its results reveal that ustadz (teachers) in the pesantren (Islamic Boarding Schools) tend to act more as communicators in entrepreneurship learning. The message packaging strategy, which includes religious lessons, general lessons, entrepreneurship, and life skills, was delivered in three ways. The first is applying the local content curriculum to the formal learning process, the second is integrating entrepreneurship values with extracurricular activities, and the third is conveying a message of independence and responsibility in daily life within the pesantren environment. Meanwhile, the channels used is face-to-face communication and the media. The communicants involved were students of Classes 10, 11 and 12. The effects of the communication process contribute to the domains of cognition, affection, and psychomotor.
Perfil do paciente com fratura mandibular em Salvador/BA
Authors: Mascarenhas Batista de Jesus Andreza , Silva de Souza Ravelle , Karoline Araújo Alves Dultra Fátima , de Almeida Dultra Joaquim
Published: September 2024

Introdução: As fraturas mandibulares envolvem importantes estruturas da face e prejudicam a função e a estética do indivíduo e, quando não tratadas adequadamente, comprometem sua saúde física e mental. Objetivo: Este estudo pretende traçar o perfil epidemiológico de pacientes com fraturas mandibulares tratados cirurgicamente em um hospital público em Salvador/BA (Brasil). Métodos: Trata-se de um estudo retrospectivo que analisou um livro de registro com dados clínicos de pacientes com fraturas mandibulares tratados cirurgicamente, que foram coletados e analisados por meio de...
Reconstruções orbitárias tardias assistidas por planejamento virtual
Authors: Dallazen Eduardo , Koto Murai Melissa , Degani Battistetti Guilherme , Farnezi Bassi Ana Paula , Perez Faverani Leonardo
Published: September 2024

﻿Introdução: Fraturas orbitárias frequentemente resultam em problemas estéticos e funcionais, como alteração da posição do globo ocular, enoftalmia e diplopia, tornando a reconstrução da cavidade orbitária desafiadora. A decisão sobre o momento da intervenção (imediata, precoce ou tardia) depende da gravidade e dos sintomas, com controvérsias na literatura sobre os prognósticos das abordagens. Tecnologias como CAD/CAM e realidade aumentada são úteis para o planejamento cirúrgico, melhorando a precisão e eficiência. Objetivo: O objetivo desse artigo é relatar dois casos...
Developing a Moderation Community of Practice
Authors: Von Konsky Brian , Watkins Annette , Broadley Tania
Published: September 2024

This paper reports on a study to evaluate technology-based processes for assessment moderation. The aim was to evaluate standard features found in an institutional Learning Management System, and their compatibility with the values and practices of a large teaching team. The process used an online discussion board forum for tutors, the paring of more experienced tutors with those new to the process, and further meetings conducted in both face-to-face and web conferencing environments. Online rubrics were used for assessing student work and the provision of feedback. A focus group conducted after marking was concluded and the analysis of the discussion board forum demonstrated a strong community of practice with a shared understanding of assessment requirements.
The importance of power dynamics in the development of asynchronous online learning communities
Authors: Vlachopoulos Panos
Published: September 2024

This research explored how a more student-directed learning design can support the creation of togetherness and belonging in a community of distance learners in formal higher education. Postgraduate students in a New Zealand School of Education experienced two different learning tasks as part of their online distance learning studies. The tasks centered around two online asynchronous discussions each for the same period of time and with the same group of students, but following two different learning design principles. All messages were analyzed using a two- step analysis process, content analysis and social network analysis. Although the findings showed a balance of power between the tutor and the students in the first high e-moderated activity, a better pattern of group interaction and community feeling was found in the low e-moderated activity. The paper will discuss the findings in terms of the implications for learning design and the role of the tutor.
The changing role of learned bodies and membership organisations
Authors: Deepwell Maren , Slater John
Published: September 2024

With the extensive changes to funding and employment security now underway worldwide, membership bodies and learned and professional associations are finding that their role is changing so as better to represent their members’ views and respond to their needs. In the United Kingdom (UK), members show increasing interest in acquiring and retaining professional standing. As government selective funding decreases, activities are being displaced from the centre to within the community with the membership body taking an increased organisational and broker role. A new governmental focus on accountability and impact is changing members’ priorities leading to revised activities by learned bodies. This paper discusses the changes necessary for professional bodies to continue to lead in the changing climate.
Sustainable learning through formative online assessment
Authors: Nagel Lynnette , Van Eck Lanise
Published: September 2024

Due to pressure to deliver more Chartered Accountants, the pass-rate of first-year accounting students had to increase. Students who did not take accounting at school particularly needed extra tuition and support to reach the required standard. Poor success rates could be attributed to insufficient theoretical learning and poor time management characterized by cramming before tests. The intervention that aimed to redress those problems was weekly online quizzes that students could complete in their own time that contained feedback and easily understood explanations. In order to create and sustain an adequate database of suitable questions, the tutors who facilitated additional work sessions and understood the pitfalls in the theory, helped the lecturers to compile the questions and participated in quality control. Quizzes and feedback helped students to pace themselves, understand the terms and prepare for tests. The pass-rate increased from 57 to 75%.
Game-like digital training tools
Authors: McLean Gregor , Wise Lisa , Williams Benedict
Published: September 2024

This paper explores the principles of skill acquisition and training transfer within the context of game-like digital training tools, expanding on previous research using an instrument scanning task in novice versus experienced pilots. While previous work demonstrated a game-like training tool is capable of developing high levels of performance within the game environment, initial findings suggest the likelihood of practical transfer to a real world environment is strongly dependent on the nature of the cognitive and perceptual skills developed. This paper investigates whether instrument scanning skills developed within a static training task transfer to a more dynamic video-based task. Despite strong performance within the static environment, preliminary data suggest a lesser degree of transfer when more dynamic perceptual skills are targeted. Findings are discussed broadly in terms of the principles of skill acquisition and training transfer, and how these principles may apply to game-like digital training tools.
Multidiscipline role-play in a 3D virtual learning environment
Authors: McDonald Marcus , Ryan Tracii , Sim Jenny , James Jennifer , Maude Philip , Scutter Sheila , Wood Denise
Published: September 2024

Three-dimensional virtual learning environments (3DVLEs), such as Second Life, have been used in education for some time. Although many writers have addressed where, how, and why 3DVLEs are applied in education, only a few articles have concentrated on the coalface of running a learning project within them. This paper looks at the experience of using Second Life to conduct a multi-discipline healthcare role-playing project with a large cohort of university students. It aims to add to the body of evidence highlighting the technical and logistical difficulties in running such a project, and attempts to offer solutions and advice on directions of problem solving. This paper will also add to best practices concerning the use of 3DVLEs in higher education.
Transcriptional and morphological responses following distinct muscle contraction protocols for Snell dwarf (Pit1dw/dw) mice
Authors: Rader Erik P. , McKinstry Kimberly A. , Baker Brent A.
Published: September 2024

The Snell dwarf mouse (Pit1dw/dw), an animal model of congenital combined pituitary hormone deficiency, displays skeletal muscle weakness. While enhanced responsivity to repeated exposures of muscle contractions have been documented for Snell dwarf mice, the response following single exposure to distinct contraction protocols remained uncharacterized. The purpose of this study was to investigate the muscle recovery of Snell dwarf and control littermate mice following a single exposure to two separate protocols—an intermittent slow velocity (30°/s) contraction protocol or a continuous rapid velocity (500°/s) contraction protocol. Following both protocols for control mice, torque values were 30% and 80% of pre‐protocol values at 5 min and 3 days, respectively. At 10 days, performance returned to baseline for the 30°/s protocol and were depressed for the 500°/s protocol. For Snell dwarf mice following both protocols, torques were depressed to 5% of pre‐protocol values at 5 min and returned to baseline by 3 days. Recovery following the 30°/s protocol for control mice and both protocols for Snell dwarf mice coincided with increased transcriptional output, upregulation of cytokine‐mediated signaling genes, and a distribution shift to smaller muscle fibers with reduced area per nucleus. These features represent efficacious remodeling ubiquitous across distinct contraction paradigms in the context of thePit1mutation.
Impact of surgical aortic valve replacement and transcatheter aortic valve implantation on cardiovascular and cerebrovascular controls: A pilot study
Authors: Bari Vlasta , Gelpi Francesca , Cairo Beatrice , Anguissola Martina , Acerbi Elena , Squillace Mattia , De Maria Beatrice , Bertoldo Enrico Giuseppe , Fiolo Valentina , Callus Edward , De Vincentiis Carlo , Bedogni Francesco , Ranucci Marco , Porta Alberto
Published: September 2024

Surgical aortic valve replacement (SAVR) and transcatheter aortic valve implantation (TAVI) are options in severe aortic valve stenosis (AVS). Cardiovascular (CV) and cerebrovascular (CBV) control markers, derived from variability of heart period, systolic arterial pressure, mean cerebral blood velocity and mean arterial pressure, were acquired in 19 AVS patients (age: 76.8 ± 3.1 yrs, eight males) scheduled for SAVR and in 19 AVS patients (age: 79.9 + 6.5 yrs, 11 males) scheduled for TAVI before (PRE) and after intervention (POST, <7 days). Left ventricular function was preserved in both groups. Patients were studied at supine resting (REST) and during active standing (STAND). We found that: (i) both SAVR and TAVI groups featured a weak pre‐procedure CV control; (ii) TAVI ensured better CV control; (iii) cerebral autoregulation was working in PRE in both SAVR and TAVI groups; (iv) SAVR and TAVI had no impact on the CBV control; (v) regardless of group, CV and CBV control markers were not influenced by STAND in POST. Even though the post‐procedure preservation of both CV and CBV controls in TAVI group might lead to privilege this procedure in patients at higher risk, the missing response to STAND suggests that this advantage could be insignificant.
Four eyes, two truths: Explaining heterogeneity in perceived severity of digital hate against immigrants
Authors: Kirchmair Thomas , Koban Kevin , Matthes Jörg
Published: September 2024

Drawing on theories related to interpersonal and intergroup behavior, this study investigated effects of personality traits (i.e., empathy and identity insecurity) and attitudes (i.e., anti-migration attitudes and social dominance orientation) on the perceived severity of digital hate against immigrants in Austria. Findings of autoregressive path modeling using two-wave panel data revealed that empathic suffering and egalitarianism positively predicted perceived severity, while anti-migrant attitudes exhibited a negative prediction. In terms of interactions between personality and attitudes, we observed that the prediction of empathic suffering becomes less relevant for egalitarian individuals, which indicates an overwriting process that might be a promising way to counteract socially harmful digital hate perceptions. Implications for research on annotation tasks and hate interventions are discussed.