bluuebunny/crossref_metadata_2025 huggingface dataset:
Advances in Electrochemical Energy Devices Constructed with Tungsten Oxide-Based Nanomaterials
Authors: Han Wenfang , Shi Qian , Hu Renzong
Published: March 2021

Tungsten oxide-based materials have drawn huge attention for their versatile uses to construct various energy storage devices. Particularly, their electrochromic devices and optically-changing devices are intensively studied in terms of energy-saving. Furthermore, based on close connections in the forms of device structure and working mechanisms between these two main applications, bifunctional devices of tungsten oxide-based materials with energy storage and optical change came into our view, and when solar cells are integrated, multifunctional devices are accessible. In this article, we have reviewed the latest developments of tungsten oxide-based nanostructured materials in various kinds of applications, and our focus falls on their energy-related uses, especially supercapacitors, lithium ion batteries, electrochromic devices, and their bifunctional and multifunctional devices. Additionally, other applications such as photochromic devices, sensors, and photocatalysts of tungsten oxide-based materials have also been mentioned. We hope this article can shed light on the related applications of tungsten oxide-based materials and inspire new possibilities for further uses.
Hierarchical Nanocauliflower Chemical Assembly Composed of Copper Oxide and Single-Walled Carbon Nanotubes for Enhanced Photocatalytic Dye Degradation
Authors: Sapkota Kamal Prasad , Islam Md. Akherul , Hanif Md. Abu , Akter Jeasmin , Lee Insup , Hahn Jae Ryang
Published: March 2021

We present the fabrication and proficient photocatalytic performance of a series of heterojunction nanocomposites with cauliflower-like architecture synthesized from copper(II) oxide (CuO) nanocrystals and carbon nanotubes with single walls (SWCNTs). These unique photocatalysts were constructed via simplistic recrystallization succeeded by calcination and were labeled as CuOSC-1, CuOSC-2, and CuOSC-3 (representing the components; CuO and SC for SWCNTs, and the calcination time in hours). The photocatalytic potency of the fabricated nanocomposites was investigated on the basis of their capability to decompose methylene blue (MB) dye under visible-light irradiation. Every as-synthesized nanocomposite was effective photocatalyst for the photodecomposition of an MB solution. Moreover, CuOSC-3 exhibited the best photocatalytic activity, with 96% degradation of the visible-light irradiated MB solution in 2 h. Pure CuO nanocrystals generated through the same route and pure SWCNTs were used as controls, where the photocatalytic actions of the nanocomposite samples were found to be remarkably better than that of either the pure CuO or the pure SWCNTs. The recycling proficiency of the photocatalysts was also explored; the results disclosed that the samples could be applied for five cycles without exhibiting a notable change in photocatalytic performance or morphology.
Synthesis, Characterization, Anti-Cancer Analysis of Sr0.5Ba0.5DyxSmxFe8−2xO19 (0.00 ≤ x ≤ 1.0) Microsphere Nanocomposites
Authors: Al-Jameel Suhailah S. , Almessiere Munirah A. , Khan Firdos A. , Taskhandi Nedaa , Slimani Yassine , Al-Saleh Najat S. , Manikandan Ayyar , Al-Suhaimi Ebtesam A. , Baykal Abdulhadi
Published: March 2021

There is enormous interest in combining two or more nanoparticles for various biomedical applications, especially in anti-cancer agent delivery. In this study, the microsphere nanoparticles were prepared (MSNPs) and their impact on cancer cells was examined. The MSNPs were prepared by using the hydrothermal method where strontium (Sr), barium (Ba), dysprosium (Dy), samarium (Sm), and iron oxide (Fe8−2xO19) were combined, and dysprosium (Dy) and samarium (Sm) was substituted with strontium (Sr) and barium (Ba), preparing Sr0.5Ba0.5DyxSmxFe8−2xO19 (0.00 ≤ x ≤ 1.0) MSNPs. The microspheres were characterized by X-ray powder diffraction (XRD), high-resolution transmission electron microscopy (HR-TEM), transmission electron microscopy (TEM), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX) techniques. The diffraction pattern of nanohexaferrites (NHFs) reflected the signature peaks of the hexagonal structure. The XRD revealed a pure hexagonal structure without any undesired phase, which indicated the homogeneity of the products. The crystal size of the nanoparticles were in the range of 22 to 36 nm by Scherrer’s equation. The SEM of MSNPs showed a semi-spherical shape with a high degree of aggregation. TEM and HR-TEM images of MSNPs verified the spherical shape morphology and structure that approved an M-type hexaferrite formation. The anti-cancer activity was examined on HCT-116 (human colorectal carcinoma) and HeLa (cervical cancer cells) using MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay and post-48 h treatment of MSNPs caused a dose-dependent inhibition of HCT-116 and HeLa cell proliferation and growth. Conversely, no significant cytotoxic effect was observed on HEK-293 cells. The treatments of MSNPs also induced cancer cells DNA disintegration, as revealed by 4′,6-diamidino-2-phenylindole (DAPI) staining. Finally, these findings suggest that synthesized MSNPs possess potential inhibitory actions on cancerous cells without harming normal cells.
Color Changes in Ag Nanoparticle Aggregates Placed in Various Environments: Their Application to Air Monitoring
Authors: Ozaki Koichi , Nishiyama Fumitaka , Takahiro Katsumi
Published: March 2021

Fresh Ag nanoparticles (NPs) dispersed on a transparent SiO2 exhibit an intense optical extinction band originating in localized surface plasmon resonance (LSPR) in the visible range. The intensity of the LSPR band weakened when the Ag NPs was stored in ambient air for two weeks. The rate of the weakening and the LSPR wavelength shift, corresponding to visual chromatic changes, strongly depended on the environment in which Ag NPs were set. The origin of a chromatic change was discussed along with both compositional and morphological changes. In one case, bluish coloring followed by a prompt discoloring was observed for Ag NPs placed near the ventilation fan in our laboratory, resulted from adsorption of large amounts of S and Cl on Ag NP surfaces as well as particle coarsening. Such color changes deduce the presence of significant amounts of S and Cl in the environment. In another case, a remarkable blue-shift of the LSPR band was observed for the Ag NPs stored in the desiccator made of stainless steel, originated in the formation of CN and/or HCN compounds and surface roughening. Their color changed from maroon to reddish, suggesting that such molecules were present inside the desiccator.
Characteristics and Photovoltaic Applications of Au-Doped ZnO–Sm Nanoparticle Films
Authors: Saleem Muhammad , Irshad Kashif , Ur Rehman Saif , Javed M. Sufyan , Hasan Mohd Abul , Ali Hafiz Muhammad , Ali Amjad , Malik Muhammad Zeeshan , Islam Saiful
Published: March 2021

Au-doped ZnO–samarium nitrate (Sm) nanoparticles with fixed concentrations of Sm (1 wt %) and various concentrations of Au (0.0, 0.5, 1.0 and 1.5 wt %) were prepared and used as photoelectrodes to enhance the photovoltaic efficiency of dye-sensitized solar cells (DSSCs). The cell fabricated with 1.5 wt % of Au-doped ZnO–Sm nanoparticles film achieved an optimal efficiency of 4.35%, which is about 76% higher than that of 0.0 wt % of Au-doped ZnO–Sm-based cell (2.47%). This increase might be due to the formation of a blocking layer at the ZnO–Sm/Au interface, which inhibits the recombination of electrons. This increase may also be attributed to the addition of rare-earth ions in ZnO to enhance the non-absorbable wavelength region of light via up/down-conversion of near-infrared and ultraviolet radiations to visible emission and reduce the recombination loss of electron in the cell. The efficiency of cells may be increased by the blocking layer and up/down-conversion process and thus promote the overall performance of the cells. This work indicates that Au-doped ZnO–Sm nanoparticle films have the potential to increase the performance of DSSCs.
Therapeutic Implications of Diet in Inflammatory Bowel Disease and Related Immune-Mediated Inflammatory Diseases
Authors: Jiang Yan , Jarr Karolin , Layton Cosima , Gardner Christopher D. , Ashouri Judith F. , Abreu Maria T. , Sinha Sidhartha R.
Published: March 2021

Despite being a focal issue to patients, the effect of diet on adult inflammatory bowel disease (IBD) remains underexplored with limited guidance. While promising clinical trials are currently underway, there is a need for further evidence-based recommendations. As such, we summarize the current evidence on various diets used in the treatment of IBD and also explore the potential applications of dietary data from related immune-mediated inflammatory diseases (IMIDs), such as rheumatoid arthritis and psoriasis, to provide additional information to inform IBD providers. To date, there have been multiple diets investigated as adjunctive therapy in IBD, but many associated studies are small, non-randomized, and not controlled. Mediterranean, vegetarian/vegan, and reduced-calorie/fasting diets have been studied and have shown some positive results in other IMIDs, which may suggest potential applicability to those with IBD, but larger, well-designed clinical trials are needed for further guidance. Gluten-free and low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP)diets do not appear to have an impact on IBD disease activity, but low FODMAP may potentially be helpful for those with concurrent functional gastrointestinal symptoms. Specific carbohydrate diets have been mainly assessed in children but show some potential in small adult studies.
Effect of Trilobatin from Lithocarpus polystachyus Rehd on Gut Microbiota of Obese Rats Induced by a High-Fat Diet
Authors: Shen Hailiang , Huang Linhua , Dou Huating , Yang Yali , Wu Houjiu
Published: March 2021

Trilobatin was identified as the primary bioactive component in the Lithocarpus polystachyus Rehd (LPR) leaves. This study explored the antiobesity effect of trilobatin from LPR leaves and its influence on gut microbiota in obese rats. Results showed that trilobatin could significantly reduce body and liver weight gain induced by a high-fat diet, and the accumulation of perirenal fat, epididymal fat, and brown fat of SD (Male Sprague–Dawley) obese rats in a dose-independent manner. Short-chain fatty acids (SCFAs) concentrations increased, especially the concentration of butyrate. Trilobatin supplementation could significantly increase the relative abundance of Lactobacillus, Prevotella, CF231, Bacteroides, and Oscillospira, and decrease greatly the abundance of Blautia, Allobaculum, Phascolarctobacterium, and Coprococcus, resulting in an increase of the ratio of Bacteroidetes to Firmicutes (except the genera of Lactobacillus and Oscillospira). The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway predicted by the Phylogenetic Investigation of Communities by Reconstruction of Unobserved States (PICRUSt) indicated the different relative metabolic pathways after trilobatin supplementation. This study may reveal the contribution of gut microbiota to the antiobesity effect of trilobatin from LPR leaves and predict the potential regulatory mechanism for obesity induced by a high-fat diet.
Leading Factors for Weight Gain during COVID-19 Lockdown in a Spanish Population: A Cross-Sectional Study
Authors: Sánchez Enric , Lecube Albert , Bellido Diego , Monereo Susana , Malagón María , Tinahones Francisco , on behalf of the Spanish Society for the Study of Obesity
Published: March 2021

The increase in sedentary behaviors during the COVID-19-induced lockdown may have led to a significant weight gain. To investigate this hypothesis, a representative sample of the Spanish adult population comprising 1000 subjects was enrolled in a cross-sectional study between 26 May and 10 June 2020. Computer-assisted telephone interviews were conducted consisting of 29 questions on the topic of lifestyle habits during the lockdown. The cohort comprised 51.5% women and 51% overweight or obese subjects and had a mean age of 50 ± 18 years. Of the respondents, 44.5% self-reported weight gain during the lockdown; of these, 58.0% were women, 69.9% had previous excess weight, 44.7% lived with a relative who also gained weight, and 73.5 experienced increased appetite. Further, an increased consumption of energy-dense products was found relative to respondents who did not gain weight (p ≤ 0.016 for all). Additionally, respondents were unaware that obesity is a poor prognostic factor for COVID-19 infection, lived in smaller flats, and had a lower level of education and lower monthly income. The factors independently associated with weight gain were female gender, previous overweight or obesity, lack of food care, increased appetite, and increased consumption of sugar-sweetened beverages, alcoholic beverages, and snacks (p ≤ 0.023 for all). Should another lockdown be mandated, extra caution is warranted to prevent weight gain.
A Mechanistic Study of the Antiaging Effect of Raw-Milk Cheese Extracts
Authors: Cardin Guillaume , Poupet Cyril , Bonnet Muriel , Veisseire Philippe , Ripoche Isabelle , Chalard Pierre , Chauder Anne , Saunier Etienne , Priam Julien , Bornes Stéphanie , Rios Laurent
Published: March 2021

Many studies have highlighted the relationship between food and health status, with the aim of improving both disease prevention and life expectancy. Among the different food groups, fermented foods a have huge microbial biodiversity, making them an interesting source of metabolites that could exhibit health benefits. Our previous study highlighted the capacity of raw goat milk cheese, and some of the extracts recovered by the means of chemical fractionation, to increase the longevity of the nematode Caenorhabditis elegans. In this article, we pursued the investigation with a view toward understanding the biological mechanisms involved in this phenomenon. Using mutant nematode strains, we evaluated the implication of the insulin-like DAF-2/DAF-16 and the p38 MAPK pathways in the phenomenon of increased longevity and oxidative-stress resistance mechanisms. Our results demonstrated that freeze-dried raw goat milk cheese, and its extracts, induced the activation of the DAF-2/DAF-16 pathway, increasing longevity. Concerning oxidative-stress resistance, all the extracts increased the survival of the worms, but no evidence of the implication of both of the pathways was highlighted, except for the cheese-lipid extract that did seem to require both pathways to improve the survival rate. Simultaneously, the cheese-lipid extract and the dried extract W70, obtained with water, were able to reduce the reactive oxygen species (ROS) production in human leukocytes. This result is in good correlation with the results obtained with the nematode.
Central Neurocircuits Regulating Food Intake in Response to Gut Inputs—Preclinical Evidence
Authors: Browning Kirsteen N. , Carson Kaitlin E.
Published: March 2021

The regulation of energy balance requires the complex integration of homeostatic and hedonic pathways, but sensory inputs from the gastrointestinal (GI) tract are increasingly recognized as playing critical roles. The stomach and small intestine relay sensory information to the central nervous system (CNS) via the sensory afferent vagus nerve. This vast volume of complex sensory information is received by neurons of the nucleus of the tractus solitarius (NTS) and is integrated with responses to circulating factors as well as descending inputs from the brainstem, midbrain, and forebrain nuclei involved in autonomic regulation. The integrated signal is relayed to the adjacent dorsal motor nucleus of the vagus (DMV), which supplies the motor output response via the efferent vagus nerve to regulate and modulate gastric motility, tone, secretion, and emptying, as well as intestinal motility and transit; the precise coordination of these responses is essential for the control of meal size, meal termination, and nutrient absorption. The interconnectivity of the NTS implies that many other CNS areas are capable of modulating vagal efferent output, emphasized by the many CNS disorders associated with dysregulated GI functions including feeding. This review will summarize the role of major CNS centers to gut-related inputs in the regulation of gastric function with specific reference to the regulation of food intake.
Acanthamoeba Keratitis, Pathology, Diagnosis and Treatment
Authors: Fanselow Nicholas , Sirajuddin Nadia , Yin Xiao-Tang , Huang Andrew J. W. , Stuart Patrick M.
Published: March 2021

Acanthamoeba keratitis is an unusual corneal infection that is recently increasing in frequency and is often contracted by contact lens wearers, someone who experienced recent eye trauma, or someone exposed to contaminated waters. Acanthamoeba survive in air, soil, dust, and water. Therefore, eye trauma and poor contact lens hygiene practices lead to the entrapment of debris and thus infection. Acanthamoeba keratitis results in severe eye pain, inflammation, and defects of the epithelium and stroma that can potentially result in vision loss if not diagnosed early and treated promptly. The disease can be diagnosed using corneal scrape/biopsy, polymerase chain reactions, impression cytology, or in vivo confocal microscopy. Once diagnosed, it is usually treated with an antimicrobial combination therapy of biguanide and aromatic diadine eye drops for several months. Advanced stages of the disease result in vision loss and the need for corneal transplants. Avoiding the risk factors and diagnosing the disease early are the most effective ways to combat Acanthamoeba keratitis.
Chronicles of Nanoerythrosomes: An Erythrocyte-Based Biomimetic Smart Drug Delivery System as a Therapeutic and Diagnostic Tool in Cancer Therapy
Authors: Javed Shamama , Alshehri Sultan , Shoaib Ambreen , Ahsan Waquar , Sultan Muhammad Hadi , Alqahtani Saad Saeed , Kazi Mohsin , Shakeel Faiyaz
Published: March 2021

Recently, drug delivery using natural biological carriers has emerged as one of the most widely investigated topics of research. Erythrocytes, or red blood cells, can act as potential carriers for a wide variety of drugs, including anticancer, antibacterial, antiviral, and anti-inflammatory, along with various proteins, peptides, enzymes, and other macromolecules. The red blood cell-based nanocarrier systems, also called nanoerythrosomes, are nanovesicles poised with extraordinary features such as long blood circulation times, the ability to escape immune system, the ability to release the drug gradually, the protection of drugs from various endogenous factors, targeted and specified delivery of drugs, as well as possessing both therapeutic and diagnostic applications in various fields of biomedical sciences. Their journey over the last two decades is escalating with fast pace, ranging from in vivo to preclinical and clinical studies by encapsulating a number of drugs into these carriers. Being biomimetic nanoparticles, they have enhanced the stability profile of drugs and their excellent site-specific targeting ability makes them potential carrier systems in the diagnosis and therapy of wide variety of tumors including gliomas, lung cancers, breast cancers, colon cancers, gastric cancers, and other solid tumors. This review focuses on the most recent advancements in the field of nanoerythrosomes, as an excellent and promising nanoplatform for the novel drug delivery of various drugs particularly antineoplastic drugs along with their potential as a promising diagnostic tool for the identification of different tumors.
Photoprotective Properties of Eumelanin: Computational Insights into the Photophysics of a Catechol:Quinone Heterodimer Model System
Authors: Frederick Victoria C. , Ashy Thomas A. , Marchetti Barbara , Ashfold Michael N. R. , Karsili Tolga N. V.
Published: March 2021

Melanins are skin-centered molecular structures that block harmful UV radiation from the sun and help protect chromosomal DNA from UV damage. Understanding the photodynamics of the chromophores that make up eumelanin is therefore paramount. This manuscript presents a multi-reference computational study of the mechanisms responsible for the experimentally observed photostability of a melanin-relevant model heterodimer comprising a catechol (C)–benzoquinone (Q) pair. The present results validate a recently proposed photoinduced intermolecular transfer of an H atom from an OH moiety of C to a carbonyl-oxygen atom of the Q. Photoexcitation of the ground state C:Q heterodimer (which has a π-stacked “sandwich” structure) results in population of a locally excited ππ* state (on Q), which develops increasing charge-transfer (biradical) character as it evolves to a “hinged” minimum energy geometry and drives proton transfer (i.e., net H atom transfer) from C to Q. The study provides further insights into excited state decay mechanisms that could contribute to the photostability afforded by the bulk polymeric structure of eumelanin.
Phytodepuration of Nitrate Contaminated Water Using Four Different Tree Species
Authors: Regni Luca , Bartucca Maria Luce , Pannacci Euro , Tei Francesco , Del Buono Daniele , Proietti Primo
Published: March 2021

Water pollution by excessive amounts of nitrate (NO3−) has become a global issue. Technologies to clean up nitrate-contaminated water bodies include phytoremediation. In this context, this research aimed to evaluate four tree species (Salix alba L., Populus alba L., Corylus avellana L. and Sambucus nigra L.) to remediate nitrate-contaminated waters (100 and 300 mg L−1). Some physiological parameters showed that S. alba L. and P. alba L. increased particularly photosynthetic activity, chlorophyll content, dry weight, and transpired water, following the treatments with the above NO3− concentrations. Furthermore, these species were more efficient than the others studied in the phytodepuration of water contaminated by the two NO3− levels. In particular, within 15 days of treatment, S. alba L. and P. alba L. removed nitrate quantities ranging from 39 to 78%. Differently, C. avellana L. and S. nigra L. did not show particular responses regarding the physiological traits studied. Nonetheless, these species removed up to 30% of nitrate from water. In conclusion, these data provide exciting indications on the chance of using S. alba L. and P. alba L. to populate buffer strips to avoid NO3− environmental dispersion in agricultural areas.
Deciphering the Proteotoxic Stress Responses Triggered by the Perturbed Thylakoid Proteostasis in Arabidopsis
Authors: Nishimura Kenji , Nakagawa Reiko , Hachisuga Chisato , Nakajima Munekage Yuri
Published: March 2021

Here, we explored heat dependent thylakoid FtsH protease substrates and investigated proteotoxicity induced by thermal damage and processive protease dysfunction on the thylakoid membrane. Through our thylakoid enriched proteome analysis and biochemical experiments, carbonylated stromal proteins were suggested as possible FtsH targets. Furthermore, we observed in the thylakoid fractions in the absence of FtsH stromal reactive oxygen species-detoxifying enzymes, as well as heat shock proteins and chaperones, which are known to be upregulated at the transcriptional level when this protease is absent, which is called the damaged protein response, resembling unfolded protein response in eukaryotic cells. Interestingly, the thylakoid-enriched high-density fractions included stromal translation factors and RNA-binding proteins, along with aminoacyl-tRNA synthetase, reminiscent of the formation of stress granules. Unexpectedly, extraplastid proteins such as mitochondrial chaperones, peroxidase, tricarboxylic acid cycle and respiratory chain enzymes, as well as cytosolic ribosomes, translation factors, heat shock proteins, antioxidants and metabolic enzymes, were also found deposited in the high-density fractions depending on the loss of thylakoid FtsH, with more prominent effects of thermal stress on the cytosolic proteins. This may reflect intracellular adaptation to the proteotoxic influences from the organelle.
Sustainable Processing of Floral Bio-Residues of Saffron (Crocus sativus L.) for Valuable Biorefinery Products
Authors: Stelluti Stefania , Caser Matteo , Demasi Sonia , Scariot Valentina
Published: March 2021

Tepals constitute the most abundant bio-residues of saffron (Crocus sativus L.). As they are a natural source of polyphenols with antioxidant properties, they could be processed to generate valuable biorefinery products for applications in the pharmaceutical, cosmetic, and food industries, becoming a new source of income while reducing bio-waste. Proper storage of by-products is important in biorefining and dehydration is widely used in the herb sector, especially for highly perishable harvested flowers. This study aimed to deepen the phytochemical composition of dried saffron tepals and to investigate whether this was influenced by the extraction technique. In particular, the conventional maceration was compared with the Ultrasound Assisted Extraction (UAE), using different solvents (water and three methanol concentrations, i.e., 20%, 50%, and 80%). Compared to the spice, the dried saffron tepals showed a lower content of total phenolics (average value 1127.94 ± 32.34 mg GAE 100 g−1 DW) and anthocyanins (up to 413.30 ± 137.16 mg G3G 100 g−1 DW), but a higher antioxidant activity, which was measured through the FRAP, ABTS, and DPPH assays. The HPLC-DAD analysis detected some phenolic compounds (i.e., ferulic acid, isoquercitrin, and quercitrin) not previously found in fresh saffron tepals. Vitamin C, already discovered in the spice, was interestingly detected also in dried tepals. Regarding the extraction technique, in most cases, UAE with safer solvents (i.e., water or low percentage of methanol) showed results of phenolic compounds and vitamin C similar to maceration, allowing an improvement in extractions by halving the time. Thus, this study demonstrated that saffron tepals can be dried maintaining their quality and that green extractions can be adopted to obtain high yields of valuable antioxidant phytochemicals, meeting the requirement for a sustainable biorefining.
Yield and Selectivity Improvement in the Synthesis of Carbonated Linseed Oil by Catalytic Conversion of Carbon Dioxide
Authors: González Martínez David Alejandro , Vigueras Santiago Enrique , Hernández López Susana
Published: March 2021

Carbonation of epoxidized linseed oil (CELO) containing five-membered cyclic carbonate (CC5) groups has been optimized to 95% by reacting epoxidized linseed oil (ELO) with carbon dioxide (CO2) and tetrabutylammonium bromide (TBAB) as catalysts. The effect of reaction variables (temperature, CO2 pressure, and catalyst concentration) on the reaction parameters (conversion, carbonation and selectivity) in an autoclave system was investigated. The reactions were monitored, and the products were characterized by Fourier Transform Infrared Spectroscopy (FT-IR), carbon-13 nuclear magnetic resonance (13C-NMR) and proton nuclear magnetic resonance (1H-NMR) spectroscopies. The results showed that when carrying out the reaction at high temperature (from 90 °C to 120 °C) and CO2 pressure (60–120 psi), the reaction’s conversion improves; however, the selectivity of the reaction decreases due to the promotion of side reactions. Regarding the catalyst, increasing the TBAB concentration from 2.0 to 5.0 w/w% favors selectivity. The presence of a secondary mechanism is based on the formation of a carboxylate ion, which was formed due to the interaction of CO2 with the catalyst and was demonstrated through 13C-NMR and FT-IR. The combination of these factors makes it possible to obtain the largest conversion (96%), carbonation (95%), and selectivity (99%) values reported until now, which are obtained at low temperature (90 °C), low pressure (60 psi) and high catalyst concentration (5.0% TBAB).
Testing the Accuracy of the Cell-Set Model Applied on Vane-Type Sub-Boundary Layer Vortex Generators
Authors: Portal-Porras Koldo , Fernandez-Gamiz Unai , Aramendia Iñigo , Teso-Fz-Betoño Daniel , Zulueta Ekaitz
Published: March 2021

Vortex Generators (VGs) are applied before the expected region of separation of the boundary layer in order to delay or remove the flow separation. Although their height is usually similar to that of the boundary layer, in some applications, lower VGs are used, Sub-Boundary Layer Vortex Generators (SBVGs), since this reduces the drag coefficient. Numerical simulations of sub-boundary layer vane-type vortex generators on a flat plate in a negligible pressure gradient flow were conducted using the fully resolved mesh model and the cell-set model, with the aim on assessing the accuracy of the cell-set model with Reynolds-Averaged Navier-Stokes (RANS) and Large Eddy Simulation (LES) turbulence modelling techniques. The implementation of the cell-set model has supposed savings of the 40% in terms of computational time. The vortexes generated on the wake behind the VG; vortical structure of the primary vortex; and its path, size, strength, and produced wall shear stress have been studied. The results show good agreements between meshing models in the higher VGs, but slight discrepancies on the lower ones. These disparities are more pronounced with LES. Further study of the cell-set model is proposed, since its implementation entails great computational time and resources savings.
Chromatic Change in Copper Oxide Layers Irradiated with Low Energy Ions
Authors: Kobayashi Takuya , Nishiyama Fumitaka , Takahiro Katsumi
Published: March 2021

The color of a thin copper oxide layer formed on a copper plate was transformed from reddish-brown into dark blue-purple by irradiation with 5 keV Ar+ ions to a fluence as low as 1 × 1015 Ar+ cm−2. In the unirradiated copper oxide layer, the copper valence state of Cu2+ and Cu+ and/or Cu0 was included as indicated by the presence of a shake-up satellite line in a photoemission spectrum. While for the irradiated one, the satellite line decreased in intensity, indicating that irradiation resulted in the reduction from Cu2+ to Cu+ and/or Cu0. Furthermore, nuclear reaction analysis using a 16O(d, p)17O reaction with 0.85 MeV deuterons revealed a significant loss of oxygen (5 × 1015 O atoms cm−2) in the irradiated layer. Thus, the chromatic change observed in the present work originated in the irradiation-induced reduction of a copper oxide.
Service Robots in the Healthcare Sector
Authors: Holland Jane , Kingston Liz , McCarthy Conor , Armstrong Eddie , O’Dwyer Peter , Merz Fionn , McConnell Mark
Published: March 2021

Traditionally, advances in robotic technology have been in the manufacturing industry due to the need for collaborative robots. However, this is not the case in the service sectors, especially in the healthcare sector. The lack of emphasis put on the healthcare sector has led to new opportunities in developing service robots that aid patients with illnesses, cognition challenges and disabilities. Furthermore, the COVID-19 pandemic has acted as a catalyst for the development of service robots in the healthcare sector in an attempt to overcome the difficulties and hardships caused by this virus. The use of service robots are advantageous as they not only prevent the spread of infection, and reduce human error but they also allow front-line staff to reduce direct contact, focusing their attention on higher priority tasks and creating separation from direct exposure to infection. This paper presents a review of various types of robotic technologies and their uses in the healthcare sector. The reviewed technologies are a collaboration between academia and the healthcare industry, demonstrating the research and testing needed in the creation of service robots before they can be deployed in real-world applications and use cases. We focus on how robots can provide benefits to patients, healthcare workers, customers, and organisations during the COVID-19 pandemic. Furthermore, we investigate the emerging focal issues of effective cleaning, logistics of patients and supplies, reduction of human errors, and remote monitoring of patients to increase system capacity, efficiency, resource equality in hospitals, and related healthcare environments.
Aerosol Trends during the Dusty Season over Iran
Authors: Yousefi Robabeh , Wang Fang , Ge Quansheng , Lelieveld Jos , Shaheen Abdallah
Published: March 2021

This study assessed the aerosol climatology over Iran, based on the monthly data of aerosol optical depth (AOD) derived from the reanalysis-based Modern Era Retrospective Analysis for Research and Applications (MERRA-2) and the satellite-based Moderate Resolution Imaging Spectroradiometer (MODIS). In addition, sea level pressure, wind speed, temperature, relative humidity, precipitation, and soil moisture from the ERA5 reanalysis dataset were applied to investigate the climate-related effects on temporal AOD changes. Our analysis identified positive and negative AOD trends during 2000–2010 and 2010–2018, respectively, which are likely linked to aeolian dust changes. The dust-driven AOD trends were supported by changes in the Ångström exponent (AE) and fine mode fraction (FMF) of aerosols over Iran. During the early period (2000–2010), results of AOD-meteorology correlation analyses suggest reduced soil moisture, leading to increased dust emissions, whereas our results suggest that during the later period (2010–2018) an increase of soil moisture led to decreased AOD levels. Soil moisture appears to be a key factor in dust mobilization in the region, notably in southwestern Iran, being influenced by adjacent mineral dust sources. These phenomena were affected by large-scale sea level pressure transformations and the associated meteorology in the preceding winter seasons. Using a multiple linear regression model, AOD variability was linked to various meteorological factors in different regions. Our results suggest that climatic variations strongly affect the dust cycle, with a strong dependence on wintertime conditions in the region.
Mapping China’s Electronic Power Consumption Using Points of Interest and Remote Sensing Data
Authors: Jin Cheng , Zhang Yili , Yang Xuchao , Zhao Naizhuo , Ouyang Zutao , Yue Wenze
Published: March 2021

Producing gridded electric power consumption (EPC) maps at a fine geographic scale is critical for rational deployment and effective utilization of electric power resources. Brightness of nighttime light (NTL) has been extensively adopted to evaluate the spatial patterns of EPC at multiple geographical scales. However, the blooming effect and saturation issue of NTL imagery limit its ability to accurately map EPC. Moreover, limited sectoral separation in applying NTL leads to the inaccurate spatial distribution of EPC, particularly in the case of industrial EPC, which is often a dominant portion of the total EPC in China. This study pioneers the separate estimation of spatial patterns of industrial and nonindustrial EPC over mainland China by jointly using points of interest (POIs) and multiple remotely sensed data in a random forests (RF) model. The POIs provided fine and detailed information about the different socioeconomic activities and played a significant role in determining industrial and nonindustrial EPC distribution. Based on the RF model, we produced industrial, non-industrial, and overall EPC maps at a 1 km resolution in mainland China for 2011. Compared against statistical data at the county level, our results showed a high accuracy (R2 = 0.958 for nonindustrial EPC estimation, 0.848 for industrial EPC estimation, and 0.913 for total EPC). This study indicated that the proposed RF-based method, integrating POIs and multiple remote sensing data, can markedly improve the accuracy for estimating EPC. This study also revealed the great potential of POIs in mapping the distribution of socioeconomic parameters.
Research on Instrument Visibility of Ozone Wind Imaging Interferometer
Authors: Zhang Chunmin , Du Xiao , Yan Tingyu , Li Guixiu
Published: March 2021

This paper discussed the principle of the ozone wind imaging interferometer developed by our group, which used remote sensing method to detect wind field and ozone concentration simultaneously, focused on the analysis and calculation of the instrument visibility and gave the theoretical representation of the instrument visibility. Computer simulation was used to analyze the influence of the system transmittance, compensation glass surface tilt and mirror surface accuracy on the instrument visibility. The results showed that the splitting ratio of the beam splitter and the field of view would affect the distribution of the instrument visibility; the tilt angle of the compensation glass surface can greatly affect the instrument visibility. We also gave the random error range of wind field speed and temperature at the instrument visibility U > 0.9. This research provides an important theoretical basis and practical guidance for the development and engineering of ozone wind imaging interferometers.
A Straightforward and Efficient Instance-Aware Curved Text Detector
Authors: Zhao Fan , Shao Sidi , Zhang Lin , Wen Zhiquan
Published: March 2021

A challenging aspect of scene text detection is to handle curved texts. In order to avoid the tedious manual annotations for training curve text detector, and to overcome the limitation of regression-based text detectors to irregular text, we introduce straightforward and efficient instance-aware curved scene text detector, namely, look more than twice (LOMT), which makes the regression-based text detection results gradually change from loosely bounded box to compact polygon. LOMT mainly composes of curve text shape approximation module and component merging network. The shape approximation module uses a particle swarm optimization-based text shape approximation method (called PSO-TSA) to fine-tune the quadrilateral text detection results to fit the curved text. The component merging network merges incomplete text sub-parts of text instances into more complete polygon through instance awareness, called ICMN. Experiments on five text datasets demonstrate that our method not only achieves excellent performance but also has relatively high speed. Ablation experiments show that PSO-TSA can solve the text’s shape optimization problem efficiently, and ICMN has a satisfactory merger effect.
Deep Learning for Transient Image Reconstruction from ToF Data
Authors: Buratto Enrico , Simonetto Adriano , Agresti Gianluca , Schäfer Henrik , Zanuttigh Pietro
Published: March 2021

In this work, we propose a novel approach for correcting multi-path interference (MPI) in Time-of-Flight (ToF) cameras by estimating the direct and global components of the incoming light. MPI is an error source linked to the multiple reflections of light inside a scene; each sensor pixel receives information coming from different light paths which generally leads to an overestimation of the depth. We introduce a novel deep learning approach, which estimates the structure of the time-dependent scene impulse response and from it recovers a depth image with a reduced amount of MPI. The model consists of two main blocks: a predictive model that learns a compact encoded representation of the backscattering vector from the noisy input data and a fixed backscattering model which translates the encoded representation into the high dimensional light response. Experimental results on real data show the effectiveness of the proposed approach, which reaches state-of-the-art performances.
Towards Motor-Based Early Detection of Autism Red Flags: Enabling Technology and Exploratory Study Protocol
Authors: Bondioli Mariasole , Chessa Stefano , Narzisi Antonio , Pelagatti Susanna , Zoncheddu Michele
Published: March 2021

Observing how children manipulate objects while they are playing can help detect possible autism spectrum disorders (ASD) at an early stage. For this purpose, specialists seek the so-called “red-flags” of motor signature of ASD for more precise diagnostic tests. However, a significant drawback to achieve this is that the observation of object manipulation by the child very often is not naturalistic, as it involves the physical presence of the specialist and is typically performed in hospitals. In this framework, we present a novel Internet of Things support in the form factory of a smart toy that can be used by specialists to perform indirect and non-invasive observations of the children in naturalistic conditions. While they play with the toy, children can be observed in their own environment and without the physical presence of the specialist. We also present the technical validation of the technology and the study protocol for the refinement of the diagnostic practice based on this technology.
Distribution and Flora of Seaweed Beds in the Coastal Waters of China
Authors: Li Xunmeng , Wang Kai , Zhang Shouyu , Feng Meiping
Published: March 2021

Seaweed plays an important role in energy production in marine, coastal, and island ecosystems. The protection of seaweed beds is a key point for coastal ecosystem health, but the community characteristics, dominant species, and distribution of seaweed beds in the coastal waters of China are still unknown. Dividing seaweed beds based on their ecological function is also required for coastal ecosystem conservation, marine development, and utilization. We conducted ecological surveys on various types of ecosystems at approximately 50 sites dedicated to the conservation of seaweed bed biodiversity in China from 2018 to 2019. These seaweed beds were classified into different flora by water temperature and the attributes of the dominant species. The study showed that Sargassum dominated the coast of China. The coverage of the genus Undaria and the genus Laminaria in the coastal waters of Liaoning and Shandong was high and gradually decreased from Zhejiang to the south. The mean biomass of the seaweed beds along the coast of China was 7.29 kg/m2, and the mean coverage was 41.25%. The height and fresh weight of the dominant species gradually decreased with the decreasing latitude. The seaweed beds were distributed from the shallow water zone to the profundal zone along the coast from north to south, and the bathymetry of seaweed beds in Hainan was below 6 m. Based on the water temperature, the attributes of the seaweed beds, the temperature attributes of the dominant species, and the seaweed’s distribution, the seaweed beds in China can be specifically divided into temperate warm water types, subtropical warm water types, and tropical warm water types. This study is relevant to the development of regulations and directives to ensure biodiversity conservation and environmental sustainability.
The Possibilities of Orthophotos Application for Calculation of Ecological Stability Coefficient Purposes
Authors: Chromčák Jakub , Bačová Daša , Pecho Pavol , Seidlová Anna
Published: March 2021

Hand in hand with the increasing interest in the environment, this work puts the spotlight on ecological stability itself. The Coefficient of Ecological Stability (CES) indicates a chosen region’s stability level that may be calculated using various methodical instructions. For exact CES determination, it is necessary to divide the area of interest correctly into predefined classes and the division quality has a direct impact on the final CES value precision which presents its informative value. For CES calculations in the past, terrestrial measurements and processing were used. Regarding the new methods of spatial data acquisition such as photogrammetry or remote sensing, there comes the question of the usage of these data for secondary purposes, such as for ecology. This articles goal is to test the use of the images taken by an Unmanned Aerial Vehicle (UAV) for CES calculation. The main objective is to highlight the possibility of a UAV to measure CES without terrestrial measurements. The second objective is to compare the actual formulas for CES calculation and to observe the differences between the results from different calculations. Another aim is to show the inconsistency of calculations which lead to legislative unification. The aim is to apply a new method of CES calculation using Geographic Information System (GIS) software and modern methods of data acquisition and to point out the benefits, mainly including the time factor, which is closely related to the terrestrial geodetic measurement, when the CES value is about to be calculated for such a spacious area.
Environmental Barriers as a Determining Factor of Physical Activity
Authors: Portela-Pino Iago , Alvariñas-Villaverde Myriam , Pino-Juste Margarita
Published: March 2021

Physical activity (PA) has been shown to be an important variable in achieving a good quality of life. The objective of this study was to determine adolescents’ perceptions of environmental barriers to PA based on age, gender, geographic location, body mass index (BMI), PA index, and whether they engage in sports or not. The sample was made up of 849 adolescents aged between 12 and 17 years old. The PA Questionnaire for Adolescents (PAQ-A) and three questions on environmental barriers were used. Among the results, we should point out that adolescents hardly perceive any environmental barriers. There are no differences in the perception of barriers neither in terms of gender nor BMI. As adolescents get older, they consider that there are few recreational spaces, that the distance is not adequate, and that there is no accessibility to them or they do not encourage walking. The adolescents who perceive the greatest barriers are those who live in settlements of 10,000–50,000 inhabitants, especially those more linked to the neighborhood and to the accessibility and availability of spaces. It seems especially important to establish health policies in order to neutralize the barriers related to the accessibility and availability of spaces and the neighborhood-related barriers.
Resilient Rural Areas and Tourism Development Paths: A Comparison of Case Studies
Authors: Ivona Antonietta , Rinella Antonella , Rinella Francesca , Epifani Federica , Nocco Sara
Published: March 2021

In the settlement network of Italian small towns (the so-called “borghi”, with a population ceiling lower than 5000 inhabitants), not lacking in discontinuities and patches, a “common thread” is increasingly noticeable, which allows to look optimistically beyond several weaknesses (economy depending on a relatively unprofitable or declining agriculture, social and economic stasis, demographic decline and consequent contraction of public and private services, hydrogeological instability, etc.): we are talking of the firm, pigheaded determination of an increasing number of local communities to become sustainable and responsible realities, get involved, and undertake a process of “hot authentication” of their milieu. Since 2013, such resilient attitude is at the heart of the National Strategy for Inner Areas (SNAI, Strategia Nazionale per le Aree Interne) aimed at promoting coordinated, multi-scalar projects of self-enhancement; in April 2019, the above innovative form of territorial planning was selected by the European Parliament as a model for the 2021–2027 programming period of the European Regional Development Fund (ERDF).This paper reviews the original and creative bottom-up enhancement process being implemented in several towns of the “Monti Dauni” sub-region, a pilot marginal area identified by Apulian regional authorities within the SNAI. In these small towns, local players aim at maximizing the opportunities of sustainable, experiential tourism by offering an uncontaminated environment, ancient knowledge, genuine flavours and deep emotions to all visitors who wish to achieve a deeper knowledge of the territorial identity instead of being mere spectators, by adopting an active and engaged attitude.