bluuebunny/crossref_metadata_2025 huggingface dataset:
Abelardo da Hora: Memórias de uma luta política pela profissionalização do artista plástico em Pernambuco
Authors: Brito Neto José Bezerra de
Published: September 2017

O objetivo deste artigo é analisar o processo de profissionalização dos artistas plásticos em Pernambuco, na segunda metade do século XX, em um período que enfeixa os debates políticos sobre o papel social do artista plástico na sociedade brasileira, gerando disputas simbólicas no campo artístico. Para tanto, irei problematizar parte da trajetória profissional do escultor pernambucano Abelardo Germano da Hora, a partir de suas memórias profissionais e políticas entre os anos de 1940 e 1970. Instrumento que traz, em suas narrativas, negociações políticas e estéticas, que ajudam a compor as diversas tramas e práticas profissionais desta categoria de intelectuais.
História Oral e as festas do Rosário: memória, ancestralidade e identidade negra em Minas Gerais
Authors: Monteiro Lívia Nascimento
Published: September 2017

O artigo procura reconstituir aspectos da festa da Congada e Moçambique de Piedade do Rio Grande – Minas Gerais, a partir das entrevistas orais realizadas com membros de diferentes gerações de congadeiros e moçambiqueiros. Reconhecida como festa do povo negro em devoção a Nossa Senhora do Rosário, Nossa Senhora das Mercêse São Benedito, a festa do Rosário de Piedade do Rio Grande rememora a escravidão e a Abolição, em seus cantos, ritmos e rituais, desde a década de 1920 até o tempo presente. A abordagem histórica desse artigo procurará demonstrar os atores políticos coletivos envolvidos na festa, a relação com a ancestralidade negra, a memória de antepassados escravos e a valorização da identidade negra em Minas Gerais.
Memórias dançantes: a (re)invenção de uma tradição por grupos de Coco de mulheres no Cariri – CE
Authors: Farias Camila Mota
Published: September 2017

Este artigo possui o objetivo de analisar como grupos de mulheres no Cariri cearense se apropriam da dança do Coco, construindo uma tradição. Utilizando as metodologias da História Oral e do trabalho de campo, realizamos nove entrevistas, com mestras e dançadeiras, que são as fontes dessa reflexão com letras de músicas de suas autorias. Por meio das memórias das mulheres, percebemos que, ao se apropriarem da dançado Coco, ressignificam a manifestação, (re)inventando uma tradição, processo que incide sobre suas identidadese produz um Coco de diferença, constituído pelo passado/presente. Assim, o artigo está dividido em três momentos: inicialmente, uma discussão sobre Dança, História Oral e Memória; em seguida, uma apresentação da dança do Coco e dos grupos estudados; e, por fim, são tecidas reflexões sobre algumas movimentações possíveis de memórias dançantes.
Vidas em canções e outras notas sobre cultura autobiográfica
Authors: Santhiago Ricardo
Published: September 2017

Neste ensaio, trato das imbricações de canções de cunho autobiográfico e da cultura autobiográfica do nosso tempo. Proponho que consideremos aquelas canções que têm como assunto a personalidade ou determinados episódios da vida de seu intérprete como uma declaração sobre si que se soma a muitas outras. Ao longo do artigo, percorro canções que descrevem ritos de passagem geográficos e simbólicos; canções que visam captar a essência de uma personagem; canções que, em conjunto, apontam para a coincidência de percepções acerca de um mesmo indivíduo.
Dossiê História Pública
Authors: Santhiago Ricardo
Published: September 2017

A historiadora britânica Jill Liddington, em uma análise sobre as feições adquiridas pela história pública em diferentes países anglo-saxões, escreveu que “a história pública certamente é (e deve continuar sendo) um templo de tolerância”. Ela se referia à variedade de vocações e definições que esta expressão inegavelmente escorregadia e controversa é capaz de abrigar. Em sua visão, o ecletismo da prática e da área de história pública, amoldadas conforme seus contextos culturais e institucionais, seria um pecado muito menos grave do que a desatenção aos temas que ela põe em foco.
“Fora Collor” e Marchas de Junho: Imprensa e construção de sentidos sobre as mobilizações populares de 1992 e 2013
Authors: Silva Sônia Maria de Meneses
Published: September 2017

Este artigo pretende realizar um estudo comparativo sobre as matérias da revista Veja nos anos de 1992 e 2013, com o objetivo de investigar as construções de sentidos relacionadas às manifestações “Fora Collor” e as Marchas de Junho de 2013. Ao estudar esses dois anos, pretendo investigar como se dá o tratamento do veículo de comunicação sobre a presença do “povo” nas ruas em ambos os casos, suas interpretações e disputas em torno desses acontecimentos emblemáticos.
Memória e narrativa visual nos álbuns de fotografias oitocentistas das famílias Ferreira Lage e Cavalcanti
Authors: Ferraz Rosane Carmanini
Published: September 2017

O presente trabalho tem como objetivo analisar a coleção de álbuns de fotografias oitocentistas das Famílias Ferreira Lage e Cavalcanti. O estudo é parte de uma pesquisa de doutorado que tem como tema o processo de formação da coleção de fotografias oitocentistas do Museu Mariano Procópio – Juiz de Fora (MG) e sua trajetória de acervo particular a acervo público. Trata-se de uma coleção de 25 álbuns, totalizando cerca de mil fotografias. A grande maioria dos álbuns pertenceu ao colecionador Alfredo Ferreira Lage, fundador do Museu Mariano Procópio e à sua prima, Amélia Machado Cavalcanti, Viscondessa de Cavalcanti. Buscamos caracterizar a coleção, identificando as narrativas visuais contidas nestes álbuns, os principais temas, formatos, técnicas e fotógrafos.
Polifonia de Vozes: o ‘multicultural planning’ como método de avaliação de políticas culturais produzidas no espaço urbano
Authors: Domingues João Luiz Pereira
Published: September 2017

O artigo se dedica à reflexão em torno da relação entre as políticas culturais, a esfera pública e seus desdobramentos territoriais, tendo como acento a discussão metodológica. O que o artigo propõe ressaltar é a possibilidade de que certos grupos e indivíduos sejam invisibilizados ou não tematizados pela aparência consensual das políticas culturais. Desta feita, tenta-se aqui traduzir um modelo metodológico de planejamento urbano para fins de diminuição do risco de atrofia de expressões culturais na cidade. Ao tematizar o universo cultural na teoria do planejamento, o Multicultural Planning rejeita a adoção dos modelos de racionalidade instrumental em favor de um modelo de reconhecimento de experiências que ressaltam diferentes leituras sobre a construção da realidade e das diversas possibilidades de organização de práticas coletivas de administração e planejamento urbano e cultural.
Identificación y evaluación del grado de satisfacción en la etapa de post-ocupación de los proyectos de viviendas económicas desde la perspectiva de los usuarios: estudio de caso peruano = Identification and evaluation of satisfaction degree in the post-occupation phase of the economic housing projects from the perspective of the users: Peruvian case study
Authors: Brioso Xavier , Patricio Wilder
Published: September 2017

ResumenEl objetivo principal de esta investigación es identificar cuáles son las necesidades más relevantes, entre ellas, las relacionadas a la sostenibilidad, que deben tomarse en cuenta en los proyectos de viviendas económicas, y evaluar el grado de satisfacción de los usuarios finales que ya habitan en este tipo de vivienda. Se describe las estrategias, herramientas, técnicas y prácticas necesarias para su identificación, para lo cual se recolecta la información de la etapa del post ocupación, en el marco del sistema Lean Project Delivery System. Para cumplir lo anterior, se siguieron los siguientes pasos: (1) Se recopiló la información de la problemática que engloba el déficit de vivienda y el planeamiento urbano existente en la zona de estudio; (2) Se diseñaron y realizaron las encuestas a la población que ya vive en viviendas sociales típicas identificando las necesidades no cubiertas, con énfasis en criterios de sostenibilidad; y (3) Se comparó los resultados de las encuestas con las necesidades de los usuarios obtenidas previamente mediante el uso de la herramienta del árbol de problemas, obteniendo conclusionesAbstractThe main objective of this research is to identify the most relevant needs, including those related to sustainability, which should be taken into account in low-income housing projects, and to assess the degree of satisfaction of the end users already living in this type of housing. It describes the strategies, tools, techniques and practices necessary for its identification, for which information is collected from the post-occupation stage, within the framework of the Lean Project Delivery System. In order to comply with the above, the following steps were followed: (1) Information was collected on the problems that comprise the housing deficit and urban planning in the study area; (2) Surveys were designed and conducted for the population that already lives in typical social housing, identifying unmet needs, with emphasis on sustainability criteria; and (3) The results of the surveys were compared with the needs of the users obtained previously through the use of the problem tree tool, obtaining conclusions and recommendations on this type of project. The case study was the typical social housing of Metropolitan Lima.
HUBUNGAN INTENSITAS PENYAKIT KARAT DENGAN PRODUKTIVITAS TANAMAN KEDELAI (Glycine max (L.) Merr.) PADA BEBERAPA VARIETAS BERBEDA
Authors: Maman Maman , Muljowati Juni Safitri , Rochmatino Rochmatino
Published: September 2017

The severity of plant disease is closely related to the development of the disease itself, including rusts caused by pathogenic fungi. This research aimed to determine the difference of rusts disease severity and to determine the correlation between rusts disease severity with the productivity of different varieties of soybean. The material used was inoculum of rusts pathogenic fungi, Phakopsora pachyrhizi Syd., and four varieties of soybean, i.e., Slamet, Lokon, Bromo, and Ringgit. This research was a split-plot design experimental with subplot was four different varieties of soybean, and the main plot was the control without the treatment of inoculation (In0). The spores suspension density of inoculum of P. pachyrhizi Syd applied was 104 spores/ml (In1). The main parameters observed in this study were the height of plants, the number of pods per plant, the number of seeds per plant, the wet and dry weight of the plant, and the total weight of 100 grains seed. The supporting parameters were the disease severity, the soil acidity, the humidity, and the air temperature. The results showed the plant with lowest rusts disease severity was Slamet variety (18,38%), and the highest was Ringgit variety (35,92%). The correlation test showed the increment of rusts disease severity reduced the number of pods and dry weight of the plant in Lokon variety.
Analysis of Women Harassment inVillages Using CETD Matrix Modal
Authors:   P.G & Research Department of Mathematics, St. Jose, S Gunalakshmi , S Johnson Savarimuthu ,   P.G & Research Department of Mathematics, St. Joseph�s college of Arts and Science (autonomous),Cuddalore , India
Published: September 2017

It is commonly understood that misbehavior intends to upset .Law says ,the repeated intentional misbehavior towards women is an offensive. The main concept of this paper can find something interesting that will make us reflect on what is done by women�s rights and gender equality. To solve such problem, in this paper we are interested to adopt CETD matrix.
Synergetic Evaluation of Project Portfolio Configuration Based on Data Envelopment Analysis
Authors: Bai Libiao , Bai Sijun , Zhai Tiantian
Published: September 2017

Project portfolio configuration (PPC) is an important approach to maintain the sustainable development of enterprises and achieve organizations’ strategy. However, the synergetic efficacy of PPC which determines the degree of the project's strategic objectives achieved is a fuzzy problem and hard to be measured. To solve this problem, this paper takes the data envelopment analysis (DEA) as the tool to measure the efficacy of PPC under deterministic conditions. First, a portfolio evaluation index system which takes financial indicators and non-financial indicators into consideration is developed based on the review of the literature; Second, an evaluation model based on DEA is built to reduce the number of decision making-unit with the perspective of synergetic theory; Then, a computational experiment is studied to verify the feasibility of this proposed model. The results of this computational experiment show that this model can effectively narrow scope of decision-making, improve the decision-making level and provide a reference to decide the DEA effective project portfolio decision-making unit. To our knowledge, this study is the first time to apply the notion of synergetic efficacy and DEA to the PPC domain. It is hoped that this paper may shed lights on any further study about PPC and enterprise competitiveness of sustainable development.
Praeruptorin A Inhibits Cervical Cancer HeLa Cell Growth and Invasion by Suppressing MMP-2 Expression and ERK1/2 Signaling
Authors: Wu Min-Hua , Lin Chia-Liang , Chiou Hui-Ling , Yang Shun-Fa , Hsieh Yi-Hsien , Liu Chung-Jung
Published: September 2017

Praeruptorin A(PA), a naturally existing pyranocumarin, is isolated from the dried root of Peucedanum praeruptorum Dunn. So far the anti-cancer effect and molecular mechanism behind Praeruptorin A action in human cervical cancer HeLa cells remain unknown. In the present study, we find that PA reduces cell proliferation and colony formation of human cervical cancer HeLa cells through inducing cell cycle arrest at G0/G1 phase. PA-upregulated p21 and p27 proteins are observed, accompanied with inhibition of cyclin D1 and S-phase kinase-associated protein 2(Skp2) proteins expression. PA could significantly inhibit migration and invasion of human HeLa cells. Meanwhile, PA significantly reduces invasive protein expression of matrix metalloproteinase-2 (MMP-2), and increases protein expression of tissue inhibitor of metalloproteinase-2 (TIMP-2). PA is observed to possess the capacity in suppressing ERK1/2 activation. PD98059 (ERK specific inhibitor) significantly enhances PA-induced downregulation of MMP-2 expression, and upregulation of TIMP-2 expression. Moreover, we found that PA treatment notably inhibits 12-O-tetradecanoylphorbol-13-acetate(TPA)-upregulated ERK1/2 activation, MMP-2 expression, cellular migration and invasion in human HeLa cells. Taken together, these findings are the first to demonstrate the anti-cancer activity of PA, which may act as a promising therapeutic agent for the treatment of human cervical cancer.
Feature Selection Algorithm Considering Trial and Individual Differences for Machine Learning of Human Activity Recognition
Authors: Omae Yuto , Takahashi Hirotaka ,   Department of Electrical Engineering, National Institute of Technology, Tokyo College 1220-2 Kunugida, Hachioji, Tokyo 193-0942, Japan,   Department of Information and Management Systems Engineering, Nagaoka University of Technology 1603-1 Kamitomioka, Nagaoka, Niigata 940-2188, Japan
Published: September 2017

In recent years, many studies have been performed on the automatic classification of human body motions based on inertia sensor data using a combination of inertia sensors and machine learning; training data is necessary where sensor data and human body motions correspond to one another. It can be difficult to conduct experiments involving a large number of subjects over an extended time period, because of concern for the fatigue or injury of subjects. Many studies, therefore, allow a small number of subjects to perform repeated body motions subject to classification, to acquire data on which to build training data. Any classifiers constructed using such training data will have some problems associated with generalization errors caused by individual and trial differences. In order to suppress such generalization errors, feature spaces must be obtained that are less likely to generate generalization errors due to individual and trial differences. To obtain such feature spaces, we require indices to evaluate the likelihood of the feature spaces generating generalization errors due to individual and trial errors. This paper, therefore, aims to devise such evaluation indices from the perspectives. The evaluation indices we propose in this paper can be obtained by first constructing acquired data probability distributions that represent individual and trial differences, and then using such probability distributions to calculate any risks of generating generalization errors. We have verified the effectiveness of the proposed evaluation method by applying it to sensor data for butterfly and breaststroke swimming. For the purpose of comparison, we have also applied a few available existing evaluation methods. We have constructed classifiers for butterfly and breaststroke swimming by applying a support vector machine to the feature spaces obtained by the proposed and existing methods. Based on the accuracy verification we conducted with test data, we found that the proposed method produced significantly higher F-measure than the existing methods. This proves that the use of the proposed evaluation indices enables us to obtain a feature space that is less likely to generate generalization errors due to individual and trial differences.
Exploitation-Oriented Learning with Deep Learning – Introducing Profit Sharing to a Deep Q-Network –
Authors: Miyazaki Kazuteru ,   National Institution for Academic Degrees and Quality Enhancement of Higher Education 1-29-1 Gakuennishimachi, Kodaira, Tokyo 185-8587, Japan
Published: September 2017

Currently, deep learning is attracting significant interest. Combining deep Q-networks (DQNs) and Q-learning has produced excellent results for several Atari 2600 games. In this paper, we propose an exploitation-oriented learning (XoL) method that incorporates deep learning to reduce the number of trial-and-error searches. We focus on a profit sharing (PS) method that is an XoL method, and combine it with a DQN to propose a DQNwithPS method. This method is compared with a DQN in Atari 2600 games. We demonstrate that the proposed DQNwithPS method can learn stably with fewer trial-and-error searches than required by only a DQN.
Changes in Sugar-Sweetened Soda Consumption, Weight, and Waist Circumference: 2-Year Cohort of Mexican Women
Authors: Stern Dalia , Middaugh Nicole , Rice Megan S. , Laden Francine , López-Ridaura Ruy , Rosner Bernard , Willett Walter , Lajous Martin
Published: September 2017

Objectives. To evaluate 2-year changes in soda consumption, weight, and waist circumference.

Methods. We followed 11 218 women from the Mexican Teachers’ Cohort from 2006 to 2008. Dietary data were collected using a semiquantitative food frequency questionnaire. Weight was self-reported, and waist circumference was self-measured. We used linear regression to evaluate changes in sugar-sweetened and sugar-free soda consumption in relation to changes in weight and waist circumference, adjusting for lifestyle and other dietary factors.

Results. Compared with no change, a decrease in sugar-sweetened soda consumption by more than 1 serving per week was associated with less weight gain (−0.4 kg; 95% confidence interval [CI] = −0.6, −0.2). Conversely, relative to no change, an increase in sugar-sweetened soda by more than 1 serving per week was associated with a 0.3-kilogram (95% CI = 0.2, 0.5) increase in weight. An increase of 1 serving per day of sugar-sweetened soda was associated with a 1.0 kg (95% CI = 0.7, 1.2; P < .001) increase in weight. The results for waist circumference were similar.

Conclusions. Moderate changes in consumption of sugar-sweetened soda over a 2-year period were associated with corresponding changes in weight and waist circumference among Mexican women.
Law Enforcement and Gun Retailers as Partners for Safely Storing Guns to Prevent Suicide: A Study in 8 Mountain West States
Authors: Runyan Carol W. , Brooks-Russell Ashley , Brandspigel Sara , Betz Marian , Tung Gregory , Novins Douglas , Agans Robert
Published: September 2017

Objectives. To examine the extent to which law enforcement agencies (LEAs) and gun retailers are willing to offer voluntary, temporary storage as a part of an overall suicide prevention effort.

Methods. We invited all LEAs and gun retailers in 8 US states to respond to questionnaires asking about their willingness to offer temporary gun storage and their recommendations to gun owners about safe storage.

Results. We collected data in 2016 from 448 LEAs and 95 retailers (response rates of 53% and 25%, respectively). Three quarters of LEAs (74.8%; 95% confidence interval [CI] = 72.1, 77.5) indicated they already provided temporary storage compared with 47.6% (95% CI = 39.2, 56.0) of retailers. LEAs were most willing to provide storage when a gun owner was concerned about the mental health of a family member. Retailers were more receptive than were LEAs to providing storage when visitors were coming or for people wanting storage while traveling. Both groups recommended locking devices within the home, but LEAs were slightly more favorable to storing guns away from the home.

Conclusions. Law enforcement agencies and gun retailers are important resources for families concerned about suicide.
Enrollment in California’s Medicaid Program After the Affordable Care Act Expansion
Authors: Wang Jing , Trivedi Amal N.
Published: September 2017

Objectives. To determine enrollment rates and predictors of enrollment for newly eligible low-income adults in California following the Affordable Care Act’s (ACA’s) Medicaid expansion.

Methods. We used data from the 2014 to 2015 California Health Interview Survey to examine post-ACA Medicaid enrollment rates and multivariable logistic regression to assess the association of demographic factors, income, and health with enrollment.

Results. We found a 78.5% enrollment rate for the newly eligible Medicaid population, translating to 3.8 million adults enrolled and 1.1 million adults who were eligible but did not enroll. Significant predictors of enrollment were participating in a public welfare program (odds ratio [OR] = 6.59; 95% confidence interval [CI] = 3.09, 14.04), having heart disease (OR = 4.03; 95% CI = 1.34, 12.15), being in the top quartile of income (OR = 3.59; 95% CI = 1.64, 7.85), enrolling in 2015 (OR = 3.28; 95% CI = 1.94, 5.56), being unemployed (OR = 2.10; 95% CI = 1.15, 3.82), and being female (OR = 1.71; 95% CI = 1.03, 2.85). We did not find significant disparities across race/ethnicity, education level, or geography.

Conclusions. Repeal of Medicaid expansion would have a substantial effect on health insurance coverage among California’s low-income adults, many of whom report chronic health conditions and no alternative sources of affordable coverage. Future research should examine the mechanisms explaining the higher enrollment rates among California’s Medicaid expansion population.
Propagandizing the Healthy, Bolshevik Life in the Early USSR
Authors: Starks Tricia A.
Published: September 2017

This essay outlines the problems facing Soviet health authorities at the inception of the People’s Commissariat of Public Health in 1918 and the innovative methods employed in sanitary enlightenment propaganda in Russia throughout the 1920s. Beset by funding issues and supply problems, the emissaries of health chose the cheapest means of health improvement (propaganda) with the most cost-effective method (prevention), and crowed of great successes even as large portions of the nation still suffered from lack of contact with sanitary authorities. Targeting Soviet citizens at every stage and space of life, the envoys of public health spread the message of prophylaxis.
Assessing the Yield and Load of Contaminants with Stream Order: Would Policy Requiring Livestock to Be Fenced Out of High‐Order Streams Decrease Catchment Contaminant Loads?
Authors: McDowell R. W. , Cox N. , Snelder T. H.
Published: September 2017

Catchment contaminant loads vary with stream order as catchment characteristics influence inputs and in‐stream processing. However, the relative influence and policy significance of these characteristics across a number of contaminants and at a national scale is unclear. We modeled the significance of catchment characteristics (e.g., climate, topography, geology, land cover), as captured by a national‐scale River Environment Classification (REC) system, and stream order in the estimation of contaminant yields. We used this model to test if potential regulation in New Zealand requiring livestock to be fenced off from large (high)‐order streams would substantially decrease catchment contaminant loads. Concentration and flow data for 1998 to 2009 were used to calculate catchment load and yields of nitrogen (N) and phosphorus (P) species, suspended sediment, and Escherichia coli at 728 water quality monitoring sites. On average, the yields of all contaminants increased with increasing stream order in catchments dominated by agriculture (generally lowland and pastoral REC land cover classes). Loads from low‐order small streams (<1 m wide, 30 cm deep, and in flat catchments dominated by pasture) exempt from potential fencing regulations accounted for an average of 77% of the national load (varying from 73% for total N to 84% for dissolved reactive P). This means that to substantially reduce contaminant losses, other mitigations should be investigated in small streams, particularly where fencing of larger streams has low efficacy.

Core Ideas

Contaminant yields increased with increasing stream order in catchments dominated by agriculture.

Fencing off high‐order streams from stock misses 77% of national contaminant load from small‐order streams.

Hence, to reduce contaminant losses to small streams, other mitigations are needed.
A Brief Review on Breast Carcinoma and Deliberation on Current Non Invasive Imaging Techniques for Detection
Authors: Vairavan Rajendaran , Abdullah Othman , Retnasamy Prema Boshani , Sauli Zaliman , Shahimin Mukhzeer Mohamad , Retnasamy Vithyacharan
Published: September 2017

Background:

Breast carcinoma is a life threatening disease that accounts for 25.1% of all carcinoma among women worldwide. Early detection of the disease enhances the chance for survival.  Discussion: This paper presents comprehensive report on breast carcinoma disease and its modalities available for detection and diagnosis, as it delves into the screening and detection modalities with special focus placed on the non-invasive techniques and its recent advancement work done, as well as a proposal on a novel method for the application of early breast carcinoma detection.

Conclusion:

This paper aims to serve as a foundation guidance for the reader to attain bird’s eye understanding on breast carcinoma disease and its current non-invasive modalities.
Determination of Flunixin in Swine Plasma, Urine and Feces by UPLCMS/ MS and its Application in the Real Samples
Authors: Yu Zugong , Luo Xiaoqing , Guo Fanxi , Zhang Zhenrui , Peng Lin
Published: September 2017

Background:

Flunixin is a Non-Steroidal Anti-Inflammatory Drug (NSAID), because it can
effectively alleviate the organism of pyrexia, inflammation and pain, it has been widely used in veterinary
practice. In order to better study flunixin in the body's absorbed, distributed, metabolized and excreted,
our team developed a UPLC-MS/MS method for determination of flunixin in swine plasma,
urine and feces.

Methods:

Flunixin was extracted from the sample by liquid-liquid extraction and cleaned-up using a
mixed-mode Oasis MCX solid-phase extraction column. Analysis was performed on UPLC-MS/MS
operating in Multiple Reaction Monitoring (MRM) mode. Internal standard was used for quantitation of
target drug.

Results:

Recoveries of fortified samples ranged from 90.2% to 101.4%, with Relative Standard Deviations
(RSD) lower than 17.0%. The Limits Of Detection (LODs) and Quantification (LOQs) in plasma
were 0.25 and 0.5 µg L-1, in urine were 0.25 and 0.5 µg L-1, and in feces were 0.5 and 1 µg kg-1, respectively.
This validated method was successfully applied to the determination of flunixin in real samples.
The half-life of flunixin after the last dose in pigs was 7.37±1.60 h after intramuscular administration of
2.2 mg/kg of flunixin, and approximately 6.8% and 1.9% of the administered dose was excreted as parent
compound in urine and feces respectively.

Conclusion:

The developed UPLC-MS/MS method for determination of flunixin in swine plasma, urine
and feces was validated and successfully applied to monitor flunixin from real samples.
An Easy Method for Screening and Detection of Laccase Activity
Authors: Dias Albino A. , Matos António J.S. , Fraga Irene , Sampaio Ana , Bezerra Rui M.F.
Published: September 2017

Objective:

An instrument-free assay was developed for simultaneous detection of laccase activity in a large number of samples as diverse as screening of laccase-producing microbial cultures or chromatographic fractions.

Method:

Dried paper discs previously impregnated with 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) were placed on a flat-bottom microplate (a simple way to avoid misidentification) and loaded with an aliquot from each sample.

Results:

Discs corresponding to samples containing laccase activity become green-bluish colored within first ten minutes of reaction, allowing direct detection through simple naked-eye inspection.

Conclusion:

As an example, this easy process was applied to the laccase purification in order to eliminate chromatographic fractions that did not contain laccase activity, thus reducing the number of spectrophotometric assays.
Interpreting the Mechanism of APOE (p.Leu167del) Mutation in the Incidence of Familial Hypercholesterolemia; An In-silico Approach
Authors: Rashidi Omran Mohammed , H.Nazar Fatima Amanullah , Alama Mohamed Nabil , Awan Zuhier Ahmed
Published: September 2017

Background:

Apolipoprotein E (APOE) gene is a ligand protein in humans which mediates the metabolism of cholesterol by binding to the low-density lipoprotein receptor (LDLR). P.Leu167del mutation in APOE gene was recently connected with Familial Hypercholesterolemia, a condition associated with premature cardiovascular disease. The consequences of this mutation on the protein structure and its receptor binding capacity remain largely unknown.

Objective:

The current study aims to further decipher the underlying mechanism of this mutation using advanced software-based algorithms. The consequences of disrupting the leucine zipper by this mutation was studied at the structural and functional level of the APOE protein.

Methods:

3D protein modeling for both APOE and LDLR (wild types), along with APOE (p.Leu167del) mutant type were generated using homology modeling template-based alignment. Structural deviation analysis was performed to evaluate the spatial orientation and the stability of the mutant APOE structure. Molecular docking analysis simulating APOE-LDLR protein interaction was carried out, in order to evaluate the impact of the mutation on the binding affinity.

Result:

Structural deviation analysis for APOE mutated model showed low degree of deviance scoring root-mean-square deviation, (RMSD) = 0.322 Å. Whereas Docking simulation revealed an enhanced molecular interaction towards the LDLR with an estimation of +171.03 kJ/mol difference in binding free energy.

Conclusion:

Thisin-silicostudy suggests that p.Leu167del is causing the protein APOE to associate strongly with its receptor, LDLR. This gain-of-function is likely hindering the ability of LDLR to be effectively recycled back to the surface of the hepatocytes to clear cholesterol from the circulation therefore leading to FH.
Analysis of Brassinosteroids in Soybean Seeds and Leaves by Liquid Chromatography-Tandem Mass Spectrometry
Authors: Li Hongxia , Trzaskalski Natasha , Neil Emery R.J.
Published: September 2017

Objective:

A simple and fast high performance liquid chromatography-electrospray tandem mass spectrometry (LC-ESI-MS/MS) method has been developed for the analysis of brassinosteroids (BRs) in plants without derivatization.

Materials:

The BRs (including castasterone, 24-epicastasterone, brassinolide and 24-epibrassinolide) have been extracted with ice cold 80% aqueous methanol solution.

Method:

Five different purification strategies have been tested for the purification and enrichment of BRs.

Conclusion:

This analytical method was sensitive, reliable, rapid and applicable to trace analysis in complex plant samples.
Effects of Banana (Musa Sapientum Linn) Consumption for Physical Strength, Metabolic Response, Oxidative Stress, Lipid Profiles, and Interleukin-23 in Healthy Men: A Preliminary Study
Authors: Leelarungrayub Jirakrit , Parameyong Arisa , Eungpinichpong Wichai , Klaphajone Jakkrit
Published: September 2017

Background:

Banana (Musa sapientum L.) is one of the many fruits that is well consumed in many countries having lots of benefits on health; however there are less evidences regarding physical performance, oxidative stress, metabolic, lipid, and pro-inflammatory cytokines in human. The aim of this study was to evaluate the effects of four weeks of banana consumption on physical strength, metabolic response, oxidative stress status, lipid profiles, and interleukin-23 in healthy men.

Methods:

Thirty healthy men were included in two week control and four week consumption periods. The parameters were evaluated by physical strength (back-leg strength, hand grip, and quadriceps strength), metabolic response to a cycling exercise test ((directed oxygen consumption (VO2), exercise time, respiratory exchange ratio (RER), ventilatory threshold (VT)), blood antioxidant status ((total antioxidant capacity (TAC), glutathione (GSH), malondialdehyde (MDA)), lipid profiles ((triglyceride, cholesterol, high density lipoprotein (HDL)), and plasma interleukin-23 (IL-23). These measures were evaluated in two times for 2 weeks before the continuous consumption of pulp from two ripe bananas, morning and evening for 4 weeks.

Results:

The results showed no statistical difference in parameters over the two week control period. After four weeks of banana consumption, the back strength, exercise time, RER, and VT were significantly improved. TAC and GSH levels were increased and MDA, triglyceride, cholesterol, and IL-23 were reduced significantly when compared to the control period.

Conclusion:

These preliminary results suggest that banana supplementation involves some physical strength, oxidative stress, lipid profile, and IL-23 levels in healthy human.
SISTEMA PARA EL MONITOREO REMOTO DE LA TEMPERATURA EN TRANSFORMADORES DE DISTRIBUCIÓN
Authors: Quintero Salazar Edwin Andrés , Mayusa López Juan Sebastián , Lozano Iván Mariscal
Published: September 2017

En este documento se presenta el desarrollo de un prototipo para el monitoreo remoto de la temperatura presente en transformadores de distribución. El sistema opera con dos señales de entrada, una proveniente de la temperatura existente en la parte interna del transformador, y otra correspondiente a la medición del valor ambiente. Posteriormente, las señales pasan a una etapa de acondicionamiento por medio de amplificadores operacionales, para finalmente ser transmitidas mediante módulos de radiofrecuencia. En el receptor, se realiza la visualización de los valores correspondientes en una pantalla de cristal líquido. El sistema se instaló en uno de los transformadores de distribución del laboratorio de máquinas eléctricas de la Universidad Tecnológica de Pereira, realizando 20 mediciones de temperatura con el sistema de medición y con el equipo patrón, a diferentes horas del día y con diferentes cargabilidades para el transformador, obteniéndose un error máximo del 3,09%.
Desarrollo de un prototipo recuperador de calor residual de lecho empacado de caliza y coque
Authors: Castaño Gallego Oscar Alberto , Acevedo alvarez Carlos Alberto , Giraldo Toro Efrén
Published: September 2017

— En el presente trabajo se diseñó un prototipo de recuperador de calor residual de lecho empacado de caliza y coque, el cual simula la captura de los gases de combustión proveniente de la chimenea de un horno vertical para calcinación de la caliza y obtener cal. El aprovechamiento de estos gases tiene por objeto precalentar un nuevo material de caliza y coque. Dichos gases son expulsados usualmente al medio ambiente con temperaturas superiores a 545 °C. El recuperador consiste en dos tubos de acero inoxidable, uno móvil y uno fijo, el tubo móvil es el recuperador como tal, el tubo fijo cumple la función de soporte, El recuperador (tubo móvil) tiene un diámetro interno de 0.096 m y una altura de 0.25 m, el gas utilizado es aire representado por las RPM del ventilador. El lecho empacado es caliza y coque en tamaños de 1 y 1.5 cm, la temperatura es la variable de interés, se registró por medio de 4 termocuplas ubicadas a 4 alturas diferentes al interior del recuperador (1, 7, 13 y 19 cm), los datos se ingresaron en las matrices de Excel avanzado 2010 en la función de regresión lineal múltiple. Excel permitió identificar 2 ecuaciones que predicen el comportamiento de la temperatura de la caliza y el coque. Se encontró que la recuperación de calor en la caliza es  del 43% y para el coque  es del 53% en un tiempo de una hora.
Comportamiento microestructural de una fundición de magnesio puro con control en la temperatura de solidificación
Authors: Medina Sergio , Isaza César , Fernández-Morales Patricia , Mendoza Emigdio , Meza J.M.
Published: September 2017

En este trabajo se estudió el comportamiento microestructural del magnesio (Mg) puro luego de ser sometido a un proceso de fundición realizado en un horno con control de atmósfera de fabricación propia y con control de la temperatura de solidificación. Con este trabajo se buscó determinar el cambio en la composición del Mg debido a la atmosfera protectora utilizada mediante SEM/EDS  y se estudió el cambio en la microestructura del Mg puro luego de realizar una solidificación en una lingotera a una temperatura de 200°C dentro del sistema de fundición, en el cuál se utilizó una atmósfera pobre en oxígeno con una mezcla de CO2 y SF6. De la evaluación composicional se evidenció un cambio en el material debido a los gases usados y los elementos con los que interactuó el Mg. Se pudo observar un cambio en la microestructura del Mg por medio de análisis de microscopía óptica y SEM, observando diferencias en la cantidad y distribución de inclusiones y partículas presentes en el Mg. Además, se observó la generación de una estructura dendrítica tras el proceso de fundición, lo cual no se evidenció en el material base. Finalmente, con el sistema de fundición fabricado se logró obtener un lingote de Mg con condiciones similares al material base, además obtener una microestructura con granos más finos y una mejor distribución de partículas en la matriz.
Mapas de Crisis, como herramienta para mejorar la respuesta en caso de la ocurrencia de un evento de carácter desastroso.
Authors: Suarez Grajales Stephania , Castaño Rojas Juan Mauricio
Published: September 2017

La gestión del riesgo ha cambiado en las últimas décadas,  anteriormente su desarrollo era más una cuestión de expertos, hoy en día incluye la participación pública permanente.Los avances en las tecnológicas de comunicación e información, pueden desempeñar un papel importante en la participación pública e institucional de la gestión del riesgo, especialmente en la respuesta un evento desastroso.Con el objetivo de mejorar la participación pública en la respuesta a un evento desastroso, se valido una aplicación para celulares Android, en la que se crearon mapas de crisis, con la participación de 50 voluntarios. Los resultados mostraron que los mapas de crisis se pueden crear fácil y rápidamente, como insumo para las organizaciones encargadas de tomar las decisiones durante la ocurrencia del evento desastroso. A partir de esta experiencia se generaron directrices que pueden ser incluidas en los protocolos de respuesta al momento de dar manejo a un evento.
LOS PROYECTOS DE DESARROLLO LO INVERSION PUBLICA Y LA INVERSION PRIVADA
Authors: Duarte Tito , Tuiz Tibana Myriam
Published: September 2017

En el artículo se presenta una forma de concebir el desarrollo económico y social de un país, mediante la integración de la planeación, los proyectos de desarrollo así como la relación armónica entre la inversión pública y privada.
Sistema difuso para la detección y diagnóstico de falla en la generación a vapor
Authors: Valencia Rivera Fabian Alexis , Sandoval Estupiñan Jose Alexander , Hernandez Cely Marlon
Published: September 2017

En la industria existen procesos que necesitan de generadores a vapor para su producción y cuando estos fallan generan pérdidas, por esta razón es necesario desarrollar un sistema de diagnostico de fallas SDDF fundamentado en  lógica borrosa para mejorar  la eficiencia del proceso y así evitar paros no programados en la producción. Mediante el modelado difuso, se analiza el comportamiento de falla, ante diferentes patrones o esquemas de funcionamiento aplicando metodologías no basadas en el conocimiento del modelo, integrado al sistema de seguridad en calderas, ejecutando de forma directa y eficaz la predicción de las fallas presentes en el proceso.
Planteamiento de un modelo logístico para reducir costos del subproceso de pintura en muebles Bovel Ltda.
Authors: Rave Arias Silvia Natalia , Arias Acevedo Diana Marcela , García Osorio Jorge Mario
Published: September 2017

Por medio de un análisis del subproceso de pintura en la fábrica Muebles Bovel Ltda. se plantea un sistema que permita minimizar los reprocesos y reducir los costos de los mismos, identificando el comportamiento de los costos presentes en ordenes de producción frente a los costos estándar definidos para el proceso, analizando el origen de los productos no conformes, y permitiendo proponer modificaciones al proceso, brindando herramientas y técnicas para generar valor agregado a los productos donde los márgenes de rentabilidad sean cada vez más altos, minimizando el alto impacto que generan los reprocesos y optimizando los recursos
Aplicación de una Metodología Estructurada para el Diseño de un Sistema de Cosecha Selectiva de Café
Authors: Ramos Giraldo Paula Jimena , García Navarro Mauricio , Hoyos Suárez Juan Felipe , Oliveros Tascón Carlos Eugenio , Sanz Uribe Juan Rodrigo
Published: September 2017

Se usó una metodología para el diseño de dispositivos que permitan el desprendimiento selectivo de frutos de café. Se tuvieron en cuenta especificaciones técnicas del producto deseado y las condiciones generadas por los frutos de café en ramas. Se generaron 33 opciones viables técnicamente de las cuales fueron seleccionadas las mejores tres calificadas para ser exploradas y finalmente seleccionar solo una para ser diseñada de manera detallada. Dicha opción fue evaluada en condiciones de laboratorio y mostró un porcentaje de desprendimiento de frutos maduros del 60% y de frutos verdes del 20%.
Modelo de capacitación sobre logística integral de almacenamiento para autoservicios de RETAIL
Authors: BALLESTEROS SILVA PEDRO PABLO , Robledo Castro Mauricio , Barrios Mendoza Hector Manuel
Published: September 2017

En este artículo se presenta un modelo de capacitación sobre logística integral de almacenamiento para los autoservicios de retail en Pereira, aplicando un  diseño metodológico de tipo analítico-descriptivo que caracterizó a los empleados relacionados con las actividades logísticas para determinar los temas de mayor impacto y cobertura que se deberían incluir en el contenido temático de esta herramienta formativa; con esta información se diseñó el modelo, buscando mejorar la cualificación del personal, y el impacto en la productividad y competitividad de las empresas que redundará en un mejor servicio para los clientes.
Nivel de madurez y grado de satisfacción de las herramientas libres para pruebas funcionales
Authors: Serna M. Edgar , Bedoya O. Wilson Andrés , López M. Katherine
Published: September 2017

Este trabajo tiene como finalidad proporcionar información acerca de algunas herramientas libres para implementar pruebas funcionales, desde la perspectiva de su utilización organizacional y como una alternativa a otras existentes. Se seleccionaron nueve herramientas a las que se aplicaron principios de selección y valoración orientados a encontrar el nivel de madurez y el grado de satisfacción. El proceso de selección y las métricas aplicadas se describen en este estudio de revisión a la web.
Líneas de Productos Software: Generando Código a Partir de Modelos y Patrones
Authors: Gaitán Peña Carlos Alberto
Published: September 2017

La Reutilización contribuye al desarrollo de herramientas de software con un alto potencial de flexibilidad, permitiendo el uso de componentes en diversos desarrollos, extendiendo las capacidades, mejoras y funcionalidades del software.  Un nuevo paradigma de desarrollo denominado “Líneas de Producto Software”, es una tendencia cada vez más utilizada por diseñadores por cuanto permiten el desarrollo de diversos modelos o sistemas software los cuales comparten entre sí características a partir de un núcleo común altamente Reutilizable.  Este Artículo es el resultado de una propuesta de diseño de un prototipo para generación de código automatizado a partir de modelos MDA y la implementación de Patrones de diseño como MVC, presentes en la mayoría de generadores de código de tipo comercial y otras herramientas GNU, las cuales transforman códigos para sistemas Transaccionales CRUD en plataformas como JSP, ASP, PHP, Ruby, etc; para entornos Web.  El uso del prototipo se planteó a partir de un Lenguaje común, pero su implementación puede extenderse a otros lenguajes o especificaciones debido a su alto grado de Usabilidad y Fiabilidad.
Ubicación óptima de condensadores en sistemas de distribución considerando incertidumbre en la demanda
Authors: Amador Soto Humberto Enrique , Hincapié Isaza Ricardo Alberto , Gallego Rendón Ramón Alfonso
Published: September 2017

En este artículo se presenta una metodología para ubicación óptima de condensadores en sistemas de distribución de media tensión, considerando incertidumbre  en la demanda. La incertidumbre en la demanda es simulada usando un flujo de carga probabilístico, el cual fue implementado con base en el método de la cadena, usado para resolver el problema operativo en el método de Montecarlo. Como método de optimización se usa una versión modificada del algoritmo genético, denominado Chu Beasley. Con el fin de potenciar  el método de optimización  se usan factores de sensibilidad que establecen una relación entre la potencia reactiva y las pérdidas del sistema. Para verificar la validez de la metodología, se usa un sistema de prueba de la literatura, con lo cual se concluye que el flujo de carga estocástico determina un valor medio de la demanda, obteniendo resultados similares a los obtenidos  con las versiones que usan flujos de carga determinísticos.
Transformaciones comunicativas en el ambiente de aprendizaje de una institución beneficiaria de CPE cuando los docentes desarrollan competencias técnicas y tecnológicas e incorporan TIC en la actividad conjunta
Authors: Amador José Francisco , Rojas García Jorge Luis , Sánchez Bedoya Héctor Gerardo , Duque Amador Montaño Eduardo
Published: September 2017

Los ambientes de aprendizaje mediados por TIC son un espacio en el que se llevan a cabo procesos educativos donde la comunicación educativa tiene incidencia en las formas de enseñar y de aprender. En esta investigación se presenten determinar qué relaciones comunicativas de transforman en el interior de los ambientes de aprendizaje cuando los docentes incorporan TIC a sus prácticas educativas. Como conclusión principal en esta investigación se encuentran transformaciones comunicativas que van de lo análogo a lo digital, de lo privado a lo público, de lo autónomo a lo colaborativo, del reconocimiento de las oportunidades educativas que ofrece un entorno cada vez más mediatizado y digitalizado, para que los docentes que desarrollan competencias técnicas y tecnológicas produzcan y propongan nuevas formas de representar y presentar la información para construir conocimiento de manera conjunta con los estudiantes en un ambiente de aprendizaje en el que las TIC se convierten en un  apoyo de los procesos educativos y formativos.