bluuebunny/crossref_metadata_2025 huggingface dataset:
Methods of Definitive Correction of Mandibular Deformity in Hemimandibular Hyperplasia Based on Radiological, Anatomical, and Topographical Measurements—Proposition of Author’s Own Protocol
Authors: Nelke Kamil , Łuczak Klaudiusz , Janeczek Maciej , Pasicka Edyta , Morawska-Kochman Monika , Guziński Maciej , Dobrzyński Maciej
Published: August 2022

In order to fully evaluate and establish the degree of bone overgrowth, various radiological studies are essential in the careful planning of the amount of surgical excision. In the presented paper, the authors use self-designed anatomo-topographical reference points for planning the surgeries. Routine panoramic radiographs and low-dose computed tomography based on anatomical landmarks help in measuring the proportions of mandibular bone overgrowth with the following preoperative anatomical landmarks: (Go-Go), (Go(Right)-Gn), (Go(Left)-Gn), and (Me–Gn). Measurements taken at selected points and landmarks (gonion-gnathion/gnathion-menton) are easy to conduct. In the authors’ proposal, the main key factor is total chin correction, which is necessary in cases of severe overgrowth; when F0 > C and Go-Gn>, there is >7 mm of vertical bone overgrowth, and the mandibular canal is positioned <5 mm from the inferior mandibular border—MIB. Larger overgrowths (>7 mm) have a greater outcome on the final symmetry than smaller overgrowths. As no guidelines are known, the authors present their own proposal.
Synergistic Effects between Ambient Air Pollution and Second-Hand Smoke on Inflammatory Skin Diseases in Chinese Adolescents
Authors: Liao Mengting , Xiao Yi , Li Shenxin , Su Juan , Li Ji , Zou Bin , Chen Xiang , Shen Minxue
Published: August 2022

Atopic dermatitis (AD), chronic hand eczema (CHE), and urticaria are common inflammatory skin diseases among adolescents and associated with air quality. However, the synergistic effects of ambient air pollution and second-hand smoke (SHS) have been unclear. We conducted a cross-sectional study including 20,138 Chinese college students where dermatological examinations and a questionnaire survey were carried out. A generalized linear mixed model was applied for the association between individualized exposure of O3, CO, NO2, SO2, PM2.5, and PM10 and the prevalence of inflammatory skin diseases. Interactions between air pollutants and SHS were analyzed. As a result, CO, NO2, SO2, PM2.5, and PM10 were positively correlated with the prevalence of AD, CHE, and urticaria. Higher frequency of SHS exposure contributed to increased probabilities of AD (p = 0.042), CHE (p < 0.001), and urticaria (p = 0.002). Of note, CO (OR: 2.57 (1.16–5.69) in third quartile) and NO2 (OR: 2.38 (1.07–5.27) in third quartile) had positive interactions with SHS for AD, and PM2.5 synergized with SHS for CHE (OR: 2.25 (1.22–4.15) for second quartile). Subgroup analyses agreed with the synergistic results. In conclusion, SHS and ambient air pollution are both associated with inflammatory skin diseases, and they have a synergistic effect on the prevalence of AD and CHE.
Accumulation Characteristics and Pollution Evaluation of Soil Heavy Metals in Different Land Use Types: Study on the Whole Region of Tianjin
Authors: Ma Tiantian , Zhang Youwen , Hu Qingbai , Han Minghai , Li Xiaohua , Zhang Youjun , Li Zhiguang , Shi Rongguang
Published: August 2022

Heavy metal pollution in soil has received much attention in recent decades. Many studies have analyzed the interaction between specific soil quality and soil heavy metal pollution. However, there is little information about the pollution status, spatial distribution and pollution sources of heavy metals in the province of Tianjin. In this paper, the distribution characteristics and pollution sources of heavy metals in soil were studied by means of the surface soil of Tianjin, as the study area and object, conducted in combination with land use types, using multiple data analysis and multivariate statistics, while the pollution levels were evaluated by various indices. The results showed the mean contents of the seven heavy metals of the studied elements followed an increasing order of Cd (0.15 mg/kg) < As (11.9 mg/kg) < Cu (24.3 mg/kg) = Pb (24.3 mg/kg) < Ni (27.9 mg/kg) < Cr (70.7 mg/kg) < Zn (79.1 mg/kg). The median values of Cr and Ni were lower than the background values and did not exceed the screening values at the points, and the median values of Cu, Zn and Pb were close to the background values, while the median contents of As and Cd were higher than the background values. The highest accumulation of heavy metals was found in grassland, and the coefficient of variation of heavy metal contents were higher in garden land, industrial and mining storage land, residential land and transportation land, indicating that the soil heavy metal contents under these land use types were more significantly disturbed by human factors. The evaluation results of the ground accumulation index method showed that the soil in Tianjin was free of pollution, except for Cd, which was at the non-polluted to moderately polluted level. The Nemero integrated pollution index evaluation method and the pollution load index evaluation method together showed that the integrated pollution levels of heavy metals in Tianjin soils were both at no pollution level/safety level. Apart from Cd and As, which were not correlated, the other heavy metals were correlated with each other two by two. Cd, Pb and Zn were the main pollution contributors from traffic, industry and other anthropogenic factors, while Cr and Ni were the main pollution contributors from soil parent material, and Cu was the main pollution contributor from mining and metal smelting. In addition, As was presumed to be the main source of pollution contribution from agriculture and surface runoff.
Post-Traumatic Growth and Resilience among Hospitalized COVID-19 Survivors: A Gendered Analysis
Authors: Adjorlolo Samuel , Adjorlolo Paul , Andoh-Arthur Johnny , Ahiable Emmanuel Kwadzo , Kretchy Irene Akwo , Osafo Joseph
Published: August 2022

The literature on behavioral outcomes associated with the COVID-19 pandemic is inundated with mental health burdens such as depression and stress disorders. The current study investigated gender invariance on resilience and post-traumatic growth (PTG) as positive psychological changes associated with the COVID-19 pandemic. A total of 381 survivors of the COVID-19 infection completed measurements of resilience, PTG, violence and stigma experience, and mental health problems like post-traumatic stress disorder (PTSD). The data were analyzed using descriptive statistics, correlation, multivariate regression, and a latent profile analysis. The results revealed that more than half of the participants had high scores on resilience (53.6%) and PTG (60.9%). The positive psychological changes, although independent of each other, were moderated by gender, and influenced by the negative experiences of participants such as stigma, violence, and PTSD. Latent profile analyses revealed three classes of participants, two of which were characterized by high scores on mental health problems and PTG. The clusters were invariant across gender. Surviving COVID-19 contributed to resilience and PTG. These can be targeted for intervention programs to mitigate the mental health burden occasioned by the pandemic.
Diabetes Treatment and Mental Illness: A Call for an Integrated Health Care System in Underserved Semi-Rural Malaysia
Authors: Thangiah Govindamal , Johar Hamimatunnisa , Ismail Roshidi , Reininghaus Ulrich , Bärnighausen Till , Thurairajasingam Sivakumar , Reidpath Daniel , Su Tin Tin
Published: August 2022

Diabetes mellitus (DM) management imposes a tremendous psychological burden on patients. The study investigates the association between DM treatment with blood glucose (BG) control and common mental health conditions. A cross-sectional study was conducted among 1821 individuals with DM in a community-based survey conducted in 2013. Information on respondents’ sociodemographic, mental health, DM treatment, and BG levels was collected. Multinomial logistic regression was employed to examine the association of diabetes treatment with controlled BG levels (<11.1 mmol/L) (42.5%, n = 774) or uncontrolled BG levels (34.3%, n = 625) compared with those not undergoing treatment (23.2%, n = 422) on depression anxiety, and stress. Having DM treatment and controlled BG was associated with high depressive symptoms (Relative Risk Ratio, RRR: 2.42; 95% CI 1.33–4.41) and high anxiety symptoms (1.66; 1.08–2.56) but not with perceived stress. However, treated DM with uncontrolled BG was associated with anxiety (high: 1.64; 1.05–2.56; low: 2.59; 1.10–6.09) but not depression or perceived stress. Our results suggest that being treated for DM, regardless of glucose control status, was associated with anxiety symptoms, whereas being treated with controlled BG was associated with high depressive symptoms. This situation highlights the need for integrative, multidisciplinary care for DM patients with mental health comorbidities.
Quality of Life and Conformity to Gender Norms in Women Receiving Assisted Reproductive Technologies as a Potential Indicator of Mental Health
Authors: Bueno-Sánchez Lidia , Alhambra-Borrás Tamara , Gallego-Valadés Alfonso , Garcés-Ferrer Jorge
Published: August 2022

The prevalence of depression, stress, or anxiety in people receiving assisted reproductive technologies (ART) has been demonstrated. However, knowledge about the influence of gender norms on quality of life (QofL) during infertility treatment is limited. The main objective of this study was to confirm that patients undergoing ART present a vulnerable mental state, which may be an indicator of risk. For this purpose, a quasi-experimental cross-sectional study was carried out in the Assisted Reproduction Unit of the Hospital Politécnico Universitario de la Fe (Spain) in which a total of 438 women participated: 256 in pre-treatment and 182 in treatment. Two questionnaires were administered, FertiQol and CFNI-23, assessing self-perceived QofL and conformity to gender norms, respectively. The results showed significant differences between the pre-treatment and treatment groups on the FertiQol and its subscales. Significant associations were also found between the CFNI-23 factors and the FertiQol subscales. The results suggest that gender norms and ART interfere with women’s mental health and QofL and should be considered as possible risk indicators by professionals preventively before the prenatal or perinatal stages. Future research should design prospective studies aimed at estimating the impact of clinical and sociodemographic variables on women and other groups receiving ART.
Risk Associations between Vehicular Traffic Noise Exposure and Cardiovascular Diseases: A Residential Retrospective Cohort Study
Authors: Bustaffa Elisa , Curzio Olivia , Donzelli Gabriele , Gorini Francesca , Linzalone Nunzia , Redini Marco , Bianchi Fabrizio , Minichilli Fabrizio
Published: August 2022

Environmental noise can induce detrimental health effects such as cardiovascular disease (CVD). The relationship between vehicular traffic noise pollution and CVD was investigated through a retrospective residential cohort study in the city of Pisa. Four exposure classes were defined for noise pollution, using noise propagation maps. The association between noise exposures and cause-specific mortality or hospitalization of the subjects of the cohort was calculated using the hazard ratio (HR) for night and day through a multiple time-dependent and sex-specific Cox regression adjusting for age, the socio-economic deprivation index, and traffic air pollution. Mortality excess for CVD and risk trends for a 1 decibel noise increment were observed among the most exposed women (mortality: HRnightclass4 1.15 (1.03–1.28); Trendnight 1.007 (1.002–1.012); HRdayclass4 1.14 (1.02–1.27); Trendday 1.008 (1.003–1.013)), particularly for ischaemic disease (mortality: Trendnight 1.008 (0.999–1.017); Trendday 1.009 (0.999–1.018)) and cerebrovascular disease (mortality: HRnightclass3 1.23 (1.02–1.48), HRdayclass3 1.24 (1.03–1.49)). Hospitalization analyses confirm mortality results. A decreased risk for hospitalization was also observed among the most exposed men (HRdayclass4 0.94 (0.88–1.01), particularly for ischaemic disease (HRnightclass4 0.90 (0.80–1.02); HRdayclass4 0.86 (0.77–0.97)) and cerebrovascular disease (HRnightclass4 0.89 (0.78–1.01)). Authors recommend the adoption of prevention measures aimed at mitigating noise and the activation of a monitoring of the risk profile in the Pisa population updating both the residential cohort and health data.
Hemodialysis Treatment for Patients with Lithium Poisoning
Authors: Liu Yu-Hsin , Tsai Kai-Fan , Hsu Pai-Chin , Hsieh Meng-Hsuan , Fu Jen-Fen , Wang I-Kuan , Liu Shou-Hsuan , Weng Cheng-Hao , Huang Wen-Hung , Hsu Ching-Wei , Yen Tzung-Hai
Published: August 2022

Background: Hemodialysis is often recommended to treat severe lithium poisoning. Nevertheless, the application rate of hemodialysis in patients with lithium poisoning is varied across different groups and the effect of hemodialysis is still undetermined. Therefore, this study aimed to analyze the hemodialysis rate of patients with lithium poisoning and to explore the clinical features of lithium-poisoned-patients treated or untreated with hemodialysis. Methods: Between 2001 and 2019, 36 patients treated at the Chang Gung Memorial Hospital for the management of lithium poisoning were stratified according to whether they were treated with hemodialysis (n = 7) or not (n = 29). Results: The patients were aged 50.7 ± 18.1 years. The poisoning patterns were acute on chronic (61.1%), chronic (25.0%) and acute (13.9%). The precipitating factors of dehydration and infection were noted in 36.1% and 25.0% of patients, respectively. Bipolar disorder (72.2%), depressive disorder (27.8%) and psychotic disorder (11.1%) were the top three psychiatric comorbidities. The hemodialysis group not only had a lower Glasgow Coma Scale (GCS) score (p = 0.001) but also had a higher respiratory failure rate (p = 0.033), aspiration pneumonia rate (p = 0.033) and acute kidney injury network (AKIN) score (p = 0.002) than the non-hemodialysis group. Although none of the patients died of lithium poisoning, the hemodialysis group required more endotracheal intubation (p = 0.033), more intensive care unit admission (p = 0.033) and longer hospitalization (p = 0.007) than the non-hemodialysis group. Conclusion: The analytical results revealed zero mortality rate and low hemodialysis rate (1.9%). Compared with patients without hemodialysis, patients receiving hemodialysis suffered severer lithium-associated complications and needed a more intensive care unit admission and longer hospital stay.
CCL2 Gene Expression and Protein Level Changes Observed in Response to Wingate Anaerobic Test in High-Trained Athletes and Non-Trained Controls
Authors: Maciejewska-Skrendo Agnieszka , Tarnowski Maciej , Kopytko Patrycja , Kochanowicz Andrzej , Mieszkowski Jan , Stankiewicz Błażej , Sawczuk Marek
Published: August 2022

Intensive, acute exercise may bring a large systemic inflammatory response marked by substantial increases in inflammatory cytokines and chemokines. One such chemokines–CCL2–is a key factor involved in inflammatory reaction to exercise. The direct aim of the study was to describe the changes in the CCL2 expression levels after anaerobic exercise in well-trained athletes adapted to long-term training and in non-trained participants. The expression of CCL2 mRNA was evaluated in peripheral blood MNCs and CCL2 protein level was observed in blood plasma. The changes were assessed as the response to an acute, intensive bout of exercise (Wingate Anaerobic Test) in two groups of participants: well-trained soccer players and non-trained individuals. An increase of CCL2 expression inn both mRNA and protein levels was observed. The response was greater in non-trained individuals and elevated levels of CCL2 transcripts persisted for more than 24 h after exercise. Well-trained individuals responded more modestly and the effect was attenuated relatively quickly. This shows muscular adaptation to a continuous training regime in well-trained individuals and better control of immune reactions to muscular injury. In non-training individuals, the induction of the inflammatory response was greater, suggesting presence of more serious myotrauma.
Fear of COVID-19 Impact on Professional Quality of Life among Mental Health Workers
Authors: Stefanatou Pentagiotissa , Xenaki Lida-Alkisti , Karagiorgas Ioannis , Ntigrintaki Angeliki-Aikaterini , Giannouli Eleni , Malogiannis Ioannis A. , Konstantakopoulos George
Published: August 2022

Several studies have examined the impact of the COVID-19 pandemic on healthcare workers’ mental health, but only a few have investigated its detrimental effect on the mental well-being of mental health workers (MHWs). Background: The current study aimed to explore the effect of the fear of COVID-19 (FCV-19) on professional quality of life dimensions, namely compassion satisfaction (CS), burnout (BO), and secondary traumatic stress (STS) in MHWs above and beyond sociodemographic and professional factors. Methods: Hierarchical linear regression models were employed to examine the relationship of extreme FCV-19 with CS, BO, and STS in MHWs (n = 224), after considering sociodemographic variables as potential confounding factors. Extreme FCV-19 was operationalized as a binary variable with a cut-off score of ≥16.5 considered as extreme fear. Results: We found that extreme FCV-19 in MHWs is linked with increased compassion fatigue (BO and STS), and this relationship is exacerbated by younger age in regard to BO and by female gender concerning STS. CS remains unaffected by severe FCV-19, and it is higher in older participants. Conclusion: Organizational support is required to protect MHWs’ mental well-being and ensure the quality of care they provide during prolonged crises, such as the COVID-19 pandemic. Measures that intensify a sense of safety, protection, and control against COVID-19 infections in mental health services should be included in the recommendations that may reduce BO and STS among MHWs.
Advantages of and Barriers to Crafting New Technology in Healthcare Organizations: A Qualitative Study in the COVID-19 Context
Authors: Mansour Sari , Nogues Sarah
Published: August 2022

Nursing professionals are constantly required to adapt to technological changes, and especially so in the wake of COVID-19, which has prompted the development of new digital tools. A new and specific form of job crafting in relation to new technology has recently emerged in the literature; that is, adoption job crafting. However, little is known about this specific form of job crafting, especially within the pandemic context. We aim, in this study, to explore the advantages of and barriers to adoption job crafting. We used NVivo software to analyze 42 semi-structured interviews conducted during COVID-19. Our findings revealed that nurses had proactive and positive attitudes toward new technology (adoption job crafting) to enhance efficiency, sustainability, well-being, virtual teamwork, communication, and knowledge sharing. We also identified many barriers to adoption job crafting due to several organizational obstacles, such as the lack of human resource management practices, especially training, and the characteristics of the technology used. We contribute to the literature by documenting innovative cases of and barriers to adoption job crafting, which have not been explored before. These findings stress the necessity to adopt human resources practices, especially training, to foster positive job crafting among nurses and safeguard their adaptive expertise.
Latent Class Analysis of Victimization Patterns and Associated Protective Factors among LGBTQ Youth
Authors: Valido Alberto , Rivas-Koehl Matthew , Rivas-Koehl Dane , Espelage Dorothy L. , Lawrence Timothy I. , Robinson Luz E.
Published: August 2022

Youth victimization in schools remains a fervent public health issue, despite increased awareness of this issue, and this is especially true for marginalized populations like lesbian, gay, bisexual, transgender, and queer (LGBTQ) youth. Youth violence has been studied widely, but less research has sought to understand factors protective of violence victimization, particularly protective factors shared across multiple forms of violence. In the current study, we utilized latent class analysis to test patterns of three types of victimization: peer victimization (PV), homophobic name-calling victimization (HNCV), and sexual harassment victimization (SHV). In addition, we tested protective factors associated with experiencing these types of violence. Our sample included 4778 9–11th graders in the United States, of which about 15% identified as LGBTQ. Three unique classes of victimization emerged, suggesting that concurrent forms of violence occur among some groups of adolescents. LGBTQ youth were more likely to be members of classes which demonstrated higher levels of victimization. Consistent with previous literature, medical access, counseling access, family support, peer support, and spirituality emerged as significant protective factors associated with a lower risk of victimization. We discuss the implications of our findings with specific attention to protecting the wellbeing of SGM youth.
The Use of Social Media in Children and Adolescents: Scoping Review on the Potential Risks
Authors: Bozzola Elena , Spina Giulia , Agostiniani Rino , Barni Sarah , Russo Rocco , Scarpato Elena , Di Mauro Antonio , Di Stefano Antonella Vita , Caruso Cinthia , Corsello Giovanni , Staiano Annamaria
Published: August 2022

In recent years, social media has become part of our lives, even among children. From the beginning of COVID-19 pandemic period, media device and Internet access rapidly increased. Adolescents connected Internet alone, consulting social media, mostly Instagram, TikTok, and YouTube. During “lockdown”, the Internet usage allowed communication with peers and the continuity activities such as school teaching. However, we have to keep in mind that media usage may be related to some adverse consequences especially in the most vulnerable people, such as the young. Aim of the review is to focus on risks correlated to social media use by children and adolescents, identifying spies of rising problems and engaging in preventive recommendations. The scoping review was performed according to PRISMA guidelines, searching on PubMed the terms “social media” or “social network”, “health”, and “pediatrics”. Excluding articles not pertinent, we found 68 reports. Out of them, 19 were dealing with depression, 15 with diet, and 15 with psychological problems, which appeared to be the most reported risk of social media use. Other identified associated problems were sleep, addiction, anxiety, sex related issues, behavioral problems, body image, physical activity, online grooming, sight, headache, and dental caries. Public and medical awareness must rise over this topic and new prevention measures must be found, starting with health practitioners, caregivers, and websites/application developers. Pediatricians should be aware of the risks associated to a problematic social media use for the young’s health and identify sentinel signs in children as well as prevent negative outcomes in accordance with the family.
Smokers’ Engagement Behavior on Facebook: Verbalizing and Visual Expressing the Smoking Cessation Process
Authors: Watti Jezdancher , Millner Máté , Siklósi Kata , Kiss Hedvig , Kelemen Oguz , Pócs Dávid
Published: August 2022

The “processes of change” and “motivational language” are common in smoker Facebook users’ comments under smoking cessation support contents. Smokers can combine this verbalization of the smoking cessation process with visual expression when they use comments and Facebook reactions at the same time. The aim of this study was to understand the relationship between processes of change, motivational language, and the Facebook reaction buttons. A total of 821 smokers’ comments were analyzed in the current study (n = 821), which responded to image-based smoking cessation support contents. The processes of change and the motivational language used in the investigated comments were identified. These linguistic categories were compared with the usage of reaction buttons. The Facebook users who used the “Haha” reaction button wrote a significantly higher proportion of sustain talk than those who used the “Like” or “Love” reaction buttons. The Facebook users who combined the comment and “Love” reaction wrote significantly more change talk than those who did not utilize these buttons. We suggest that the “Haha” reaction may be a negative indicator, the “Like” reaction may be a neutral indicator, and the “Love” reaction may be a positive engagement indicator in terms of the smoking cessation process during Facebook-based interventions. These results may highlight how to evaluate Facebook reactions relating to smoking cessation support contents.
From Health Campaign to Interpersonal Communication: Does Traditional Diet Culture Hinder the Communication of the Chinese Gongkuai Campaign?
Authors: Yan Jing , Ji Jing , Gao Lan
Published: August 2022

Interpersonal communication is beneficial in promoting individuals’ tendency to accept health-campaign-targeted behavior. Based on the protective action decision model, this study investigated the key factors underlying individual’s interpersonal communication on the Gongkuai campaign, which was carried out during Coronavirus disease 2019 (COVID-19). The main goal of the Gongkuai campaign was to change traditional communal eating habits and reduce public health risks. An online questionnaire survey involving 618 respondents was conducted in China after the 2020 Gongkuai campaign propagated, and the data were analyzed by using the structural equation modeling technique. The results indicated that health campaign exposure is a critical determinant of perceived campaign-related knowledge and health risk perception, which are significant predictors of interpersonal communication. Meanwhile, campaign-related knowledge can elicit risk perception. Furthermore, campaign exposure influenced interpersonal communication in ways that traditional diet culture did not predict. Risk perception was also unaffected by traditional diet culture. It is worth noting that individuals’ agreement with traditional diet culture does not hinder health campaign-generated interpersonal communication in the context of public health crisis. Based on the findings, theoretical and policy implications for motivating interpersonal communication were discussed, and research limitations were pointed out.
Spatial and Temporal Evolution and Driving Factors of Urban Ecological Well-Being Performance in China
Authors: Bian Jing , Lan Feng , Zhou Yulin , Peng Zhenzhen , Dong Mingfang
Published: August 2022

Extensive development leads to the decline of ecological well-being, and it is necessary to improve the urban ecological well-being performance (EWP). This paper adopted the Super-slack-based measure (Super-SBM) model to evaluate the EWP of 285 Chinese prefecture level cities from 2011 to 2017. The exploratory spatial data analysis method (ESDA) was used to explore the spatial and temporal evolution characteristics of the EWP, and then the spatial Durbin model (SDM) was adopted to analyze the driving factors of the EWP. The results show that the trend of the overall average EWP has experienced a stage evolution process of “upward → downward → upward”. The urban EWPs have significant spatial agglomeration and path dependence. The economic development level and technological progress had the positive impacts on the EWP, and the urbanization level, economic extroversion and industrial structure had the negative impacts on the EWP. The result reveals that there was a “U-shaped” relationship existing between urbanization level and the EWP. The negative spatial spillover effect of urbanization level on the EWP was significant. The corresponding policy implications were put forward. This study will provide strategic guidance for policy makers to optimize and enhance the urban EWP.
Obstetric Violence Is Prevalent in Routine Maternity Care: A Cross-Sectional Study of Obstetric Violence and Its Associated Factors among Pregnant Women in Sri Lanka’s Colombo District
Authors: Perera Dinusha , Munas Muzrif , Swahnberg Katarina , Wijewardene Kumudu , Infanti Jennifer J. ,   on behalf of the ADVANCE Study Group
Published: August 2022

The phenomenon of obstetric violence has been documented widely in maternity care settings worldwide, with scholars arguing that it is a persistent, common, but preventable impediment to attaining dignified health care. However, gaps remain in understanding local expressions of the phenomenon, associations with other types of violence against women, and implications for women’s trust and confidence in health providers and services. We focused on these issues in this cross-sectional study of 1314 women in Sri Lanka’s Colombo district. Specifically, in this study, we used Sinhalese and Tamil translations of the NorVold Abuse Questionnaire and the Abuse Assessment Screen to measure prevalence of women’s experiences with obstetric violence in maternity care and lifetime and pregnancy-specific domestic violence. Then, the results were interpreted by considering the women’s sociodemographic characteristics, such as age, ethnicity, and family income, to reveal previously undocumented associations between obstetric and domestic violence during pregnancy, as well as other factors associated with experiencing obstetric violence. We argue that obstetric violence is prevalent in government-sector (public) maternity care facilities in the Colombo district and is associated with young age, lower family income, non-majority ethnicity, and rural residency. Significantly, this study sheds light on a serious concern that has been underexamined, wherein women who report experiencing obstetric violence are also less likely to be asked by a health care provider about domestic violence experiences. Further research at the clinical level needs to focus on appropriate training and interventions to ensure women’s safety and cultivate relationships between patients and health care providers characterized by trust, confidence, and respect.
Tailoring Nylon 6/Acrylonitrile-Butadiene-Styrene Nanocomposites for Application against Electromagnetic Interference: Evaluation of the Mechanical, Thermal and Electrical Behavior, and the Electromagnetic Shielding Efficiency
Authors: Luna Carlos Bruno Barreto , do Nascimento Emanuel Pereira , Siqueira Danilo Diniz , Soares Bluma Guenther , Agrawal Pankaj , de Mélo Tomás Jeferson Alves , Araújo Edcleide Maria
Published: August 2022

Nylon 6/acrylonitrile-butadiene-styrene nanocomposites were prepared by mixing in a molten state and injection molded for application in electromagnetic interference shielding and antistatic packaging. Multi-wall carbon nanotubes (MWCNT) and maleic anhydride-grafted ABS compatibilizer were incorporated to improve the electrical conductivity and mechanical performance. The nanocomposites were characterized by oscillatory rheology, Izod impact strength, tensile strength, thermogravimetry, current-voltage measurements, shielding against electromagnetic interference, and scanning electron microscopy. The rheological behavior evidenced a severe increase in complex viscosity and storage modulus, which suggests an electrical percolation phenomenon. Adding 1 to 5 phr MWCNT into the nanocomposites produced electrical conductivities between 1.22 × 10−6 S/cm and 6.61 × 10−5 S/cm. The results make them suitable for antistatic purposes. The nanocomposite with 5 phr MWCNT showed the highest electromagnetic shielding efficiency, with a peak of –10.5 dB at 9 GHz and a value around –8.2 dB between 11 and 12 GHz. This was possibly due to the higher electrical conductivity of the 5 phr MWCNT composition. In addition, the developed nanocomposites, regardless of MWCNT content, showed tenacious behavior at room temperature. The results reveal the possibility for tailoring the properties of insulating materials for application in electrical and electromagnetic shielding. Additionally, the good mechanical and thermal properties further widen the application range.
Chiral Selectors in Voltammetric Sensors Based on Mixed Phenylalanine/Alanine Cu(II) and Zn(II) Complexes
Authors: Zilberg Rufina A. , Berestova Tatyana V. , Gizatov Ruslan R. , Teres Yulia B. , Galimov Miras N. , Bulysheva Elena O.
Published: August 2022

A practical application composite based on mixed chelate complexes [M(S-Ala)2(H2O)n]–[M(S-Phe)2(H2O)n] (M = Cu(II), Zn(II); n = 0–1) as chiral selectors in enantioselective voltammetric sensors was suggested. The structures of the resulting complexes were studied by XRD, ESI-MS, and IR- and NMR-spectroscopy methods. It was determined that enantioselectivity depends on the metal nature and on the structure of the mixed complex. The mixed complexes, which were suggested to be chiral selectors, were stable under the experimental conditions and provided greater enantioselectivity in the determination of chiral analytes, such as naproxen and propranolol, in comparison with the amino acids they comprise. The best results shown by the mixed copper complex [Cu(S-Ala)2]–[Cu(S-Phe)2] were: ipS/ipR = 1.27 and ΔEp = 30 mV for Nap; and ipS/ipR = 1.37 and ΔEp = 20 mV for Prp. The electrochemical and analytical characteristics of the sensors and conditions of voltammogram recordings were studied by differential pulse voltammetry. Linear relationships between the anodic current and the concentrations of Nap and Prp enantiomers were achieved in the range of 2.5 × 10−5 to 1.0 × 10−3 mol L−1 for GCE/PEC-[Cu(S-Ala)2]–[Cu(S-Phe)2] and 5.0 × 10−5 to 1.0 × 10−3 for GCE/PEC–[Zn(S-Ala)2(H2O)]–[Zn(S-Phe)2(H2O)], with detection limits (3 s/m) of 0.30–1.24 μM. The suggested sensor was used to analyze Nap and Prp enantiomers in urine and plasma samples.
Overcoming High Impedance in the Transitional Area of the Distal Great Cardiac Vein during Radiofrequency Catheter Ablation of Ventricular Arrhythmia
Authors: Chen Yan-Ru , Lin Yi-Fan , Xu Que , Zheng Cheng , He Rui-Lin , Li Jin , Li Jia , Li Yue-Chun , Lin Jia-Xuan , Lin Jia-Feng
Published: August 2022

(1) Background: Radiofrequency catheter ablation (RFCA) is an essential treatment for ventricular arrhythmia (VA). However, high impedance in the transitional area of the distal great cardiac vein (TAODGCV) often leads to ablation failure. This study aimed to explore the factors influencing impedance and identify effective ways to reduce impedance. (2) Methods: A total of 156 patients with VA arising from the TAODGCV received RFCA therapy at our center from October 2009 to August 2021 and were retrospectively analyzed. Local impedance variation during RFCA was monitored, recorded, and analyzed. (3) Results: The impedance increased from the proximal to distal portions of the TAODGCV and decreased by increasing the saline flow rate at the same site. To overcome high impedance, we implemented the following strategies: (1) Reset the upper limit impedance to 300 Ω and accelerate the saline flow rate to 60 mL/min (effective in 118 of 144 patients); (2) turn off the upper limit impedance (effective in eleven of 21 patients); (3) use high-flow-rate irrigation devices (effective in five of 15 patients); and (4) increase the upper limit temperature (effective in six of ten patients). (4) Conclusions: In the TAODGCV, local impedance is mainly influenced by the target site location and saline flow rate. We concluded several methods to overcome the high impedance and contribute to a successful ablation.
Genetic Analysis of Cardiac Syncope-Related Genes in Korean Patients with Recurrent Neurally Mediated Syncope
Authors: Lee Sung Ho , Park Jong Eun , Ki Chang-Seok , Park Seung-Jung , On Young Keun , Park Kyoung-Min , Kim June Soo
Published: August 2022

Neurally mediated syncope (NMS) is a common clinical problem. The underlying genetic factors of NMS remain controversial. We hypothesized that cardiac syncope-related genes may contribute to NMS in patients with previous frequent syncopal episodes and/or a family history of syncope. A total of 54 consecutive patients diagnosed with NMS were prospectively enrolled between 2013 and 2016. Inclusion criteria were more than five syncopal episodes with a family history of syncope (n = 17) or more than five syncopal episodes with no family history of syncope (n = 37). Ninety-eight cardiac syncope-related genes (channelopathy: 43 genes, cardiomyopathy: 50 genes, primary pulmonary hypertension: 5 genes) were screened by exome sequencing. All identified variants were classified according to the standards and guidelines by the American College of Medical Genetics and Genomics and the Association for Molecular Pathology. Of the 54 patients, 17 patients (31.5%) had a family history of syncope. Two patients (3.7%) had pathogenic and likely pathogenic variants (PV/LPV) in cardiac syncope-related genes TTN and MYH7. We investigated genetic variation in patients with frequent NMS with a positive family history of syncope in Korea. PV/LPVs in genes related to cardiomyopathy were associated with recurrent NMS in Korean patients. Closer follow-up of these patients might be needed.
Following the Beat: Imaging the Valveless Pumping Function in the Early Embryonic Heart
Authors: Wang Shang , Larina Irina V.
Published: August 2022

In vertebrates, the coordinated beat of the early heart tube drives cardiogenesis and supports embryonic growth. How the heart pumps at this valveless stage marks a fascinating problem that is of vital significance for understanding cardiac development and defects. The developing heart achieves its function at the same time as continuous and dramatic morphological changes, which in turn modify its pumping dynamics. The beauty of this muti-time-scale process also highlights its complexity that requires interdisciplinary approaches to study. High-resolution optical imaging, particularly fast, four-dimensional (4D) imaging, plays a critical role in revealing the process of pumping, instructing numerical modeling, and enabling biomechanical analyses. In this review, we aim to connect the investigation of valveless pumping mechanisms with the recent advancements in embryonic cardiodynamic imaging, facilitating interactions between these two areas of study, in hopes of encouraging and motivating innovative work to further understand the early heartbeat.
Primary Catheter-Directed Thrombolysis for Porto-Mesenteric Venous Thrombosis (PMVT) in Non-Cirrhotic Patients
Authors: Chiang Chia-Ling , Liang Huei-Lung , Chen Wen-Chi , Li Ming-Feng
Published: August 2022

Purpose: To report our thrombolytic technique, treatment strategy, and clinical outcomes for porto-mesenteric venous thrombosis (PMVT) in non-cirrhotic patients. Methods: Sixteen acute or chronic non-cirrhotic PMVT patients (mean age: 48.6 years) with imminent intestinal ischemia were enrolled from 2004 to 2020. Eight patients presented thrombus extension into the peripheral mesenteric vein, close to the venous arcade. Transhepatic catheter-directed thrombolysis (CDT) was performed by urokinase infusion (60,000–30,000 IU/h concomitant with heparin 300–400 IU/h), catheter aspiration, and/or balloon dilation/stent placement. Additional intra-arterial mesenteric infusion of urokinase (30,000 IU/h) was given in patients with the peripheral mesenteric venules involved. Transjugular intrahepatic porto-systemic shunt (TIPS) was created in patients with poor recanalization of the intrahepatic portal flow (PV). Results: The transhepatic route was adopted in all patients, with adjunct indirect mesenteric arterial thrombolytic infusion in eight patients. A total of up to 20.4 million IU urokinase was infused for 1–21 days’ treatment duration. TIPS was created in three patients with recanalization failure of the intrahepatic PV. Technical success was achieved in 100% of patients with complete recanalization of 80% and partial recanalization of 20%. No major procedure-related complications were encountered. The 30-day mortality rate was 6.7%. The overall two-year primary patency was 84.6%. Conclusions: CDT can be performed as a primary salvage treatment once the diagnosis is made. CDT via the transhepatic route with tailored thrombolytic regimen is safe and effective for both acute and chronic PMVT. TIPS creation can be preserved in non-cirrhotic PMVT patients if intrahepatic PV recanalization fails.
Age Is Only a Number Also in Hyperacute Stroke Care—But Not an Irrelevant One
Authors: Sipilä Jussi O. T.
Published: August 2022

“It is difficult to make predictions, especially about the future [...]
Outcomes of Laryngeal Cancer Surgery after Open Partial Horizontal Laryngectomies with Lateral Cervical Approach
Authors: Colizza Andrea , Ralli Massimo , Di Stadio Arianna , Cambria Francesca , Zoccali Federica , Cialente Fabrizio , Angeletti Diletta , Greco Antonio , de Vincentiis Marco
Published: August 2022

Background: Open partial horizontal laryngectomies (OPHL) are one of the surgical techniques used for the conservative management of laryngeal cancers. The aims of this study are to analyze the oncological and functional results of a group of patients affected by laryngeal squamous cell carcinoma (LSCC) treated with OPHL, performed using a minimally invasive technique. Methods: This is a prospective case–control study. We enrolled 17 consecutive patients with LSCC treated with OPHL through a lateral cervical approach (LCA). Patients were evaluated using their Penetration Aspiration Scale score (liquid, semiliquid and solid) and Voice Handicap Index (VHI) at three different endpoints: 15 days (T1), 3 months (T2), and 6 months (T2) after surgery. Results: The functional outcomes of the LCA are stackable with that of the classical anterior cervical approach in terms of respiration, swallowing, and speech. One-way ANOVA was performed to evaluate the variances of PAS and VHI scores at the three different observation points. No statistically significant differences were observed between OPHL- PAS scores for liquid (p = 0.1) at the three different observation points. A statistically significant improvement was observed in the OPHL- PAS score for semisolids and solids (p < 0.00001) between T1 and T3 (p = 0.0001) and for solids between T2 and T3 (p < 0.00001). The improvement of VHI-10 was statistically significative (p < 0.00001) at the three different observation points (T1–T2 and T2–T3). Conclusion: The LCA is a potential approach for laryngeal surgery in selected cases. The preoperative staging and planning are of the utmost importance to ensure oncological radicality. The main advantage of this approach is the preservation of the healthy tissues surrounding the larynx and the functional and oncological outcomes are stackable with the classic anterior cervical approach.
Complications of the Percutaneous Mitral Valve Edge-To-Edge Repair: Role of Transesophageal Echocardiography
Authors: Flores Guisela , Mesa Dolores , Ojeda Soledad , de Lezo Javier Suárez , Gonzalez-Manzanares Rafael , Dueñas Guillermo , Pan Manuel
Published: August 2022

The use of transcatheter edge-to-edge repair for the treatment of mitral regurgitation has markedly increased in the last few years. The rate of adverse events related to the procedure is low; however, some of the complications that may occur are potentially dangerous. Due to the growing popularity of the technique, which is no longer limited to high-volume centers, knowledge of the complications related to the procedure is fundamental. Transesophageal echocardiography has a key role in the guidance of the intervention while allowing for the avoidance of most of these adverse events, as well as enabling us to diagnose them early. In this article, we review the main complications that might present during a transcatheter mitral edge-to-edge repair procedure (tamponade, thromboembolic events, single leaflet device attachment, device embolization, vascular injury…) while highlighting key aspects of transesophageal echocardiographic monitoring in the prevention and prompt diagnosis of these complications.
The Impact of Chronic Kidney Disease on Mid-Term Outcomes after Revascularisation of Peripheral Arterial Occlusive Disease: Results from a Prospective Cohort Study
Authors: Kotov Artur , Blasche Deven A. , Peters Frederik , Pospiech Philip , Rother Ulrich , Stavroulakis Konstantinos , Remig Jürgen , Schmidt-Lauber Christian , Zeller Thomas , Görtz Hartmut , Teßarek Jörg , Behrendt Christian-Alexander
Published: August 2022

Objective: The current study aimed to determine the relationship between chronic kidney disease (CKD) and major 12-month outcomes for patients with in-hospital treatment for symptomatic peripheral arterial occlusive disease (PAOD). Methods: An analysis of the prospective longitudinal multicentric cohort study with 12-month follow-up was conducted including patients who underwent endovascular or open surgery for symptomatic PAOD at 35 German vascular centres (initial study protocol: NCT03098290). Severity of CKD was grouped into four stages combining information about the estimated glomerular filtration rate (eGFR) at baseline and dialysis dependency. Outcomes included overall mortality as well as the two composite endpoints of amputation or death, and of major cardiovascular events (MACE). 12-month incidences and adjusted hazard ratios were estimated using the Kaplan–Meier function and Cox proportional hazard models. Results: A total of 4354 patients (32% female, 69 years mean age, 68% intermittent claudication, 69% percutaneous endovascular revascularisation) were included and followed for 244 days in median. Thereof, 22% had any CKD and 5% had end stage kidney disease (ESKD) at baseline. The 12-month overall mortality rate was 3.6% (95% CI 2.3–4.9) with 96 events in the entire cohort: 147 were amputated or died (5.3%, 95% CI 5.2–5.3), and 277 had a MACE (9.5%, 95% CI 9.4–9.5). When compared with patients without kidney disease, ESKD was significantly associated with overall mortality (HR 1.9; 95% CI 1.1–3.5), amputation or death (HR 2.4; 95% CI 1.4–4.1), and MACE (HR 2.0; 95% CI 1.3–3.2). Conclusions: In the current study on mid-term outcomes after invasive revascularisation for symptomatic PAOD, one out of five patients suffered from any CKD while those few with ESKD had twice the odds of death, of amputation or death, and of major adverse cardiovascular events after twelve months. These results emphasise that concomitant CKD and its impact on outcomes should be considered by severity while mild and moderate grades should not lead to ineffectual treatment strategies.
Parametric Design and Numerical Investigation of Hydrodynamic Characteristics of a New Type of Armour Block TB-CUBE Based on SPH Method
Authors: Peng Cheng , Wang Hao , Zhang Huaqing , Chen Hanbao
Published: August 2022

Based on the open-source code DualSPHysics, a numerical model was conducted to simulate the regular wave transformation on the slope breakwater with artificial block, and the simulation results were verified according to the measured data from the physical experiment. The deviation between the numerical model and the measured data was less than 6% and 9% in wave run-up and overtopping, respectively, which demonstrated the model can reliably capture the wave evolution on the breakwater with an artificial block. Based on this verified model, the size of the artificial block was adjusted to obtain optimal wave-damping effects. Once obtained, the hydrodynamic characteristics of the optimized new artificial block TB-CUBE were further studied, and the effects of the breakwater slope, water depth in front of the breakwater, incident wave period, and the height on wave run-up were all analyzed. Finally, an empirical formula for wave run-up on this type of article block was suggested through data-fitting, for which the correlation coefficient is 0.981.