bluuebunny/crossref_metadata_2025 huggingface dataset:
Enhancing construction safety: predicting worker sleep deprivation using machine learning algorithms
Authors: Sathvik S. , Alsharef Abdullah , Singh Atul Kumar , Shah Mohd Asif , ShivaKumar G.
Published: July 2024

Sleep deprivation is a critical issue that affects workers in numerous industries, including construction. It adversely affects workers and can lead to significant concerns regarding their health, safety, and overall job performance. Several studies have investigated the effects of sleep deprivation on safety and productivity. Although the impact of sleep deprivation on safety and productivity through cognitive impairment has been investigated, research on the association of sleep deprivation and contributing factors that lead to workplace hazards and injuries remains limited. To fill this gap in the literature, this study utilized machine learning algorithms to predict hazardous situations. Furthermore, this study demonstrates the applicability of machine learning algorithms, including support vector machine and random forest, by predicting sleep deprivation in construction workers based on responses from 240 construction workers, identifying seven primary indices as predictive factors. The findings indicate that the support vector machine algorithm produced superior sleep deprivation prediction outcomes during the validation process. The study findings offer significant benefits to stakeholders in the construction industry, particularly project and safety managers. By enabling the implementation of targeted interventions, these insights can help reduce accidents and improve workplace safety through the timely and accurate prediction of sleep deprivation.
Quantified planar collagen distribution in healthy and degenerative mitral valve: biomechanical and clinical implications
Authors: Sadeghinia Mohammad Javad , Persson Robert Matongo , Ellensen Vegard Skalstad , Haaverstad Rune , Holzapfel Gerhard A. , Skallerud Bjørn , Prot Victorien , Urheim Stig
Published: July 2024

Degenerative mitral valve disease is a common valvular disease with two arguably distinct phenotypes: fibroelastic deficiency and Barlow’s disease. These phenotypes significantly alter the microstructures of the leaflets, particularly the collagen fibers, which are the main mechanical load carriers. The predominant method of investigation is histological sections. However, the sections are cut transmurally and provide a lateral view of the microstructure of the leaflet, while the mechanics and function are determined by the planar arrangement of the collagen fibers. This study, for the first time, quantitatively examined planar collagen distribution quantitatively in health and disease using second harmonic generation microscopy throughout the thickness of the mitral valve leaflets. Twenty diseased samples from eighteen patients and six control samples were included in this study. Healthy tissue had highly aligned collagen fibers. In fibroelastic deficiency they are less aligned and in Barlow’s disease they are completely dispersed. In both diseases, collagen fibers have two preferred orientations, which, in contrast to the almost constant one orientation in healthy tissues, also vary across the thickness. The results indicate altered in vivo mechanical stresses and strains on the mitral valve leaflets as a result of disease-related collagen remodeling, which in turn triggers further remodeling.
Facile synthesis of silver doped manganese oxide nanocomposite with superior photocatalytic and antimicrobial activity under visible spectrum
Authors: Elbasuney Sherif , El-Khawaga Ahmed M. , Elsayed Mohamed A. , Elsaidy Amir , Yehia M. , Correa-Duarte Miguel A.
Published: July 2024

Water pollution and antimicrobial resistance (AMR) have become two global threats; 80% of diseases and 50% of child deaths are due to poor water quality. In this study, hydrothermal processing was employed to manufacture manganese oxide nanorods. Silver dopant was deposited on the surface of manganese oxide. XRD diffractogram confirmed the facile synthesis of Ag/Mn2O3 nanocomposite. XPS survey analysis demonstrated silver content of 9.43 atom %. Photocatalytic measurements demonstrated the outstanding efficiency of the Ag-Mn2O3 compared to virgin oxide particles under visible radiation. Degradation efficiencies Mn2O3 and Ag/Mn2O3 on methyl orange (MO) dye was found to be 53% and 85% under visible spectrum. Silver dopant was found to decrease the binding energy of valence electrons; this action could support electron–hole pair generation under visible spectrum and could promote catalytic performance. Ag/Mn2O3 NPs demonstrated most effective performance (95% removal efficiency) at pH 3; this could be ascribed to the electrostatic attraction between positively charged catalyst and the negatively charged MO. Ag/Mn2O3 demonstrated enhanced antibacterial activity against Gram-positive Staphylococcus aureus (S. aureus) (19 mm ZOI), and Gram-negative Escherichiacoli (E. coli) (22 mm ZOI) respectively; the developed nanocomposite demonstrated advanced anti-film activity with inhibition percentage of 95.5% against E. coli followed by 89.5% against S. aureus.
A clinical study evaluating low dose ferrous fumarate vs. standard iron supplements in iron-deficient non-anemic to mild anemic adults
Authors: Jyothi G. S. , Shelatkar Rohit , Kalavathy H. R. , Vaidya V. G. , Sisode Manjit , Ganu Gayatri
Published: July 2024

Our study aims to validate safety and efficacy of Feroglobin capsule compared with different iron supplementations in adult subjects diagnosed with non-anemic to mild anemic iron deficiency and fatigue. Enrolled 302 participants diagnosed with non-anemic to mild anemic iron deficiency and fatigue. Group A (n = 147) received Feroglobin, Group B (n = 146) received standard of care [Haem Up Gems capsules (Ferrous fumarate) or Fericip tablets (Ferrous ascorbate)]. 293 subjects completed the study with follow-up visits on days 30, 60, and 90. Feroglobin treatment significantly increased hemoglobin levels from mean 12.43 g/dl to 13.24 g/dl in 90 days. Ferritin levels improved significantly by 442.87% compared to the standard care’s 256.67%. Fatigue scale scores reduced by 47.51%, and all presenting health complaints resolved completely. Gastrointestinal symptoms observed were similar in both the groups. Both groups exhibited moderate treatment adherence. Quality of life improved in pain and general health domains, exhibiting a good tolerability. Adverse events were unrelated to the investigational products. Feroglobin serves as an efficacious therapeutic alternative for improving hemoglobin, ferritin, and reducing fatigue with low doses compared to standard of care. However, longer-term effects of low-dose require further investigations in different target groups.
Genome scans reveal signals of selection associated with pollution in fish populations of Basilichthys microlepidotus, an endemic species of Chile
Authors: Vega-Retter Caren , Rojas-Hernández Noemi , Cortés-Miranda Jorge , Véliz David , Rico Ciro
Published: July 2024

The Maipo River catchment is one of Chile’s most polluted basins. In recent decades, discharges of untreated sewage and organic matter have caused eutrophication and water quality degradation. We employed the indigenous silverfish species Basilichthys microlepidotus as a model organism to investigate the process of adaptation and selection on genes influenced by pollution. Using variation at single nucleotide polymorphisms (SNPs), we determined the temporal stability of the population structure patterns previously identified in this species by varying SNPs. We also examined local adaptation to pollution-selected genes. Using the genotypes of 7684 loci in 180 individuals, we identified 429 and 700 loci that may be undergoing selection. We detected these loci using the FSTHET and ARLEQUIN outlier detection software, respectively. Both software packages simultaneously identified a total of 250 loci. B. microlepidotus' population structure did not change over time at contaminated or unpolluted sites. In addition, our analysis found: (i) selection of genes associated with pollution, consistent with observations in other organisms; (ii) identification of candidate genes that are functionally linked to the same biological processes, molecular functions and/or cellular components that previously showed differential expression in the same populations; and (iii) a candidate gene with differential expression and a non-synonymous substitution.
Validation of a novel NGS based BCR::ABL1 kinase domain mutation detection assay in Indian cohort
Authors: Chaudhary Pooja , Chaudhary Spandan , Patel Falguni , Patel Shiv , Vaishnani Toral , Trivedi Nikha , Patel Dhiren , Sonagara Tushar , Hirapara Ashish , Vyas Kavisha , Patel Lokesh , Kumar Raja , Chakraborty Nikkan , Sharma Divya , Suthar Jigar , Kamdar Payal , Jajodia Ekta , Ahmad Firoz , Arora Neeraj
Published: July 2024

The efficacy and treatment outcome of a CML patient are heavily dependent on BCR::ABL1 kinase domain (KD) mutation status. Next-generation sequencing technology is a bright alternative to the previously used sanger sequencing method due to its global presence in diagnostic setups, massive parallel sequencing ability, and far better sensitivity. In the present study, we have demonstrated a new protocol for kinase domain mutation analysis using the next-generation sequencing (NGS) method using the ion torrent sequencing platform. This protocol uses RNA as the starting material, followed by nested PCR to amplify the fusion transcript, which is subsequently used as a template for NGS. Initial validation and comparison of this assay with the sanger sequencing (SS) method yielded 95.23% agreement. CML samples (n = 121) with a failure to TKI response were subjected to this newly developed NGS-based assay to detect KD mutations, from which samples were found to have mutations with a sensitivity ranging from 2.32 to 93.41%. A total of 34.71% of samples (n = 42) were found to be positive for one or more KD mutations, whereas 65.29% of samples (n = 81) were found to be negative. Nine samples out of 42 positive samples, i.e., 21.42%, were found to have compound mutations. This is one of the first studies from India, which includes more than 160 samples and is analyzed by the NGS approach for KD mutation analysis.
Unlocking Cd(II) biosorption potential of Candida tropicalis XTA 1874 for sustainable wastewater treatment
Authors: Bhattacharyya Kaustav , Bhattacharjee Neelanjan , Sen Debrup , Lai Tapan Kumar , Ghosh Ananyo K. , Pal Ritesh Ranjan , Ganguly Subhadeep
Published: July 2024

Cd(II) is a potentially toxic heavy metal having carcinogenic activity. It is becoming widespread in the soil and groundwater by various natural and anthropological activities. This is inviting its immediate removal. The present study is aimed at developing a Cd(II) resistant strain isolated from contaminated water body and testing its potency in biological remediation of Cd(II) from aqueous environment. The developed resistant strain was characterized by SEM, FESEM, TEM, EDAX, FT-IR, Raman Spectral, XRD and XPS analysis. The results depict considerable morphological changes had taken place on the cell surface and interaction of Cd(II) with the surface exposed functional groups along with intracellular accumulation. Molecular contribution of critical cell wall component has been evaluated. The developed resistant strain had undergone Cd(II) biosorption study by employing adsorption isotherms and kinetic modeling. Langmuir model best fitted the Cd(II) biosorption data compared to the Freundlich one. Cd(II) biosorption by the strain followed a pseudo second order kinetics. The physical parameters affecting biosorption were also optimized by employing response surface methodology using central composite design. The results depict remarkable removal capacity 75.682 ± 0.002% of Cd(II) by the developed resistant strain from contaminated aqueous medium using 500 ppm of Cd(II). Quantitatively, biosorption for Cd(II) by the newly developed resistant strain has been increased significantly (p < 0.0001) from 4.36 ppm (non-resistant strain) to 378.41 ppm (resistant strain). It has also shown quite effective desorption capacity 87.527 ± 0.023% at the first desorption cycle and can be reused effectively as a successful Cd(II) desorbent up to five cycles. The results suggest that the strain has considerable withstanding capacity of Cd(II) stress and can be employed effectively in the Cd(II) bioremediation from wastewater.
Investigating the causal association between obesity and risk of hepatocellular carcinoma and underlying mechanisms
Authors: Chen Zhitao , Ding Chenchen , Chen Kailei , Gu Yangjun , Qiu Xiaoxia , Li Qiyong
Published: July 2024

Obesity is a global health concern and independent risk factor for cancers including hepatocellular carcinoma (HCC). However, evidence on the causal links between obesity and HCC is limited and inconclusive. This study aimed to investigate the causal relationship between obesity-related traits and HCC risk and explore underlying mechanisms using bioinformatics approaches. Two-sample Mendelian randomization analysis was conducted leveraging publicly available genome-wide association study summary data on obesity traits (body mass index, body fat percentage, waist circumference, waist-to-hip ratio, visceral adipose tissue volume) and HCC. Associations of obesity with primary mechanisms (insulin resistance, adipokines, inflammation) and their effects on HCC were examined. Differentially expressed genes in obesity and HCC were identified and functional enrichment analyses were performed. Correlations with tumor microenvironment (TME) and immunotherapy markers were analyzed. Genetically predicted higher body mass index and body fat percentage showed significant causal relationships with increased HCC risk. Overall obesity also demonstrated causal links with insulin resistance, circulating leptin levels, C-reactive protein levels and risk of severe insulin resistant type 2 diabetes. Four differentially expressed genes (ESR1, GCDH, FAHD2A, DCXR) were common in obesity and HCC. Enrichment analyses indicated their roles in processes like RNA capping, viral transcription, IL-17 signaling and endocrine resistance. They exhibited negative correlations with immune cell infiltration and immunotherapy markers in HCC. Overall obesity likely has a causal effect on HCC risk in Europeans, possibly via influencing primary mechanisms. The identified differentially expressed genes may be implicated in obesity-induced hepatocarcinogenesis through regulating cell cycle, inflammation and immune evasion. Further research on precise mechanisms is warranted.
Characteristics of retinal vascularization in reactivated retinopathy of prematurity requiring treatment and clinical outcome after reinjection of ranibizumab
Authors: Jang Ji Hye
Published: July 2024

This study aimed to determine whether the state of retinal vascularization after anti-vascular endothelial growth factor (anti-VEGF) injection can help predict the risk of reactivated retinopathy of prematurity (ROP) requiring treatment and whether repeated ranibizumab injection will be effective in such cases. We retrospectively reviewed 24 infants (43 eyes) who received ranibizumab monotherapy between January 2021 and December 2022. All eyes were classified as having non-retreated ROP or retreated ROP. The state of ROP at the time of treatment, the time required for resolution of plus disease, and the extent of vascularization at 4 and 8 weeks after treatment were analyzed. Extent of temporal retinal vascularization was measured with serial fundus images using disc-fovea distance (DF) unit and disc diameter (DD). Reactivated ROP requiring treatment occurred in six infants (25.0%) and ten eyes (23.3%) after ranibizumab treatment. The mean retreatment interval was 9.0 ± 3.3 weeks (range 4–16). In the retreated ROP group, the time required for the resolution of plus disease after primary injection was longer compared to the control group (13.3 days vs 5.2 days), with a mean ROP regression time of 3.4 weeks. All eyes in the retreated ROP showed retinal vascularization < 0.5 DF from the original site at 4 weeks after injection. In 90% of cases with retreated ROP, the extent of vascularization at 8 weeks after injection was within 1 DF from the original ROP site, and all cases showed reactivation in the posterior Zone II area. The extent of retinal neovascularization in the retreated group was an average of 0.7 DD (vs 1.7 DD) and 1.3 DD (vs 3.3 DD) at 4 and 8 weeks after injection, respectively. After ranibizumab retreatment, only one reactivated case with vitreous traction progressed to focal retinal detachment, while all other cases regressed with peripheral vascular development. The continuation of delayed retinal blood vessel development after ≥ 8 weeks may indicate a high likelihood of reactivated ROP requiring treatment. In the absence of vitreous traction, ranibizumab reinjection is likely to be effective in treating reactivated ROP requiring treatment.
Extracellular C1qbp inhibits myogenesis by suppressing NFATc1
Authors: Kim Jin-Man , Kim Ho Kyoung , Cho Han Jin , Moon Sung-Ah , Kim Yewon , Hong Jeong Yeon , Lee Seung Hun , Kim Kyunggon , Koh Jung-Min
Published: July 2024

Aging and lack of exercise are the most important etiological factors for muscle loss. We hypothesized that new factors that contribute to muscle loss could be identified from ones commonly altered in expression in aged and exercise-limited skeletal muscles. Mouse gastrocnemius muscles were subjected to mass spectrometry-based proteomic analysis. The muscle proteomes of hindlimb-unloaded and aged mice were compared to those of exercised and young mice, respectively. C1qbp expression was significantly upregulated in the muscles of both hindlimb-unloaded and aged mice. In vitro myogenic differentiation was not affected by altering intracellular C1qbp expression but was significantly suppressed upon recombinant C1qbp treatment. Additionally, recombinant C1qbp repressed the protein level but not the mRNA level of NFATc1. NFATc1 recruited the transcriptional coactivator p300, leading to the upregulation of acetylated histone H3 levels. Furthermore, NFATc1 silencing inhibited p300 recruitment, downregulated acetylated histone H3 levels, and consequently suppressed myogenic differentiation. The expression of C1qbp was inversely correlated with that of NFATc1 in the gastrocnemius muscles of exercised or hindlimb-unloaded, and young or aged mice. These findings demonstrate a novel role of extracellular C1qbp in suppressing myogenesis by inhibiting the NFATc1/p300 complex. Thus, C1qbp can serve as a novel therapeutic target for muscle loss.
Comparison of WAIC and posterior predictive approaches for N-mixture models
Authors: Gaya Heather E. , Ketz Alison C.
Published: July 2024

Hierarchical models are common for ecological analysis, but determining appropriate model selection methods remains an ongoing challenge. To confront this challenge, a suitable method is needed to evaluate and compare available candidate models. We compared performance of conditional WAIC, a joint-likelihood approach to WAIC (WAICj), and posterior-predictive loss for selecting between candidate N-mixture models. We tested these model selection criteria on simulated single-season N-mixture models, simulated multi-season N-mixture models with temporal auto-correlation, and three case studies of single-season N-mixture models based on eBird data. WAICj proved more accurate than the standard conditional formulation or posterior-predictive loss, even when models were temporally correlated, suggesting WAICj is a robust alternative to model selection for N-mixture models.
Blockchain technology and raft consensus for secure physician prescriptions and improved diagnoses in electronic healthcare systems
Authors: Abdorrahimi Behnaz , Nekouie Atefeh , Rahmani Amir Masoud , Lansky Jan , Nulíček Vladimír , Hosseinzadeh Mehdi , Moattar Mohammad Hossein
Published: July 2024

With electronic healthcare systems undergoing rapid change, optimizing the crucial process of recording physician prescriptions is a task with major implications for patient care. The power of blockchain technology and the precision of the Raft consensus algorithm are combined in this article to create a revolutionary solution for this problem. In addition to addressing these issues, the proposed framework, by focusing on the challenges associated with physician prescriptions, is a breakthrough in a new era of security and dependability for the healthcare sector. The Raft algorithm is a cornerstone that improves the diagnostic decision-making process, increases confidence in patients, and sets a new standard for robust healthcare systems. In the proposed consensus algorithm, a weighted sum of two influencing factors including the physician acceptability and inter-physicians’ reliability is used for selecting the participating physicians. An investigation is conducted to see how well the Raft algorithm performs in overcoming prescription-related roadblocks that support a compelling argument for improved patient care. Apart from its technological benefits, the proposed approach seeks to revolutionize the healthcare system by fostering trust between patients and providers. Raft’s ability to communicate presents the proposed solution as an effective way to deal with healthcare issues and ensure security.
The ethics of ChatGPT in medicine and healthcare: a systematic review on Large Language Models (LLMs)
Authors: Haltaufderheide Joschka , Ranisch Robert
Published: July 2024

With the introduction of ChatGPT, Large Language Models (LLMs) have received enormous attention in healthcare. Despite potential benefits, researchers have underscored various ethical implications. While individual instances have garnered attention, a systematic and comprehensive overview of practical applications currently researched and ethical issues connected to them is lacking. Against this background, this work maps the ethical landscape surrounding the current deployment of LLMs in medicine and healthcare through a systematic review. Electronic databases and preprint servers were queried using a comprehensive search strategy which generated 796 records. Studies were screened and extracted following a modified rapid review approach. Methodological quality was assessed using a hybrid approach. For 53 records, a meta-aggregative synthesis was performed. Four general fields of applications emerged showcasing a dynamic exploration phase. Advantages of using LLMs are attributed to their capacity in data analysis, information provisioning, support in decision-making or mitigating information loss and enhancing information accessibility. However, our study also identifies recurrent ethical concerns connected to fairness, bias, non-maleficence, transparency, and privacy. A distinctive concern is the tendency to produce harmful or convincing but inaccurate content. Calls for ethical guidance and human oversight are recurrent. We suggest that the ethical guidance debate should be reframed to focus on defining what constitutes acceptable human oversight across the spectrum of applications. This involves considering the diversity of settings, varying potentials for harm, and different acceptable thresholds for performance and certainty in healthcare. Additionally, critical inquiry is needed to evaluate the necessity and justification of LLMs’ current experimental use.
Global prevalence and correlates of mpox vaccine acceptance and uptake: a systematic review and meta-analysis
Authors: Sulaiman Sahabi Kabir , Isma’il Tsiga-Ahmed Fatimah , Musa Muhammad Sale , Makama Bello Tijjani , Sulaiman Abdulwahab Kabir , Abdulaziz Tijjani Bako
Published: July 2024

Background

Vaccination has been recommended as one of the most potent ways of controlling the mpox (formerly, monkeypox) outbreak, particularly among high-risk groups. Here, we evaluated the prevalence of mpox vaccine acceptance and uptake globally.

Methods

We searched multiple databases for peer-reviewed studies published in English from May 2022 to 25th November 2023 that evaluated mpox vaccine acceptance and/or uptake. We fit a random-effects model meta-analysis to calculate the pooled mpox vaccine acceptance and uptake rates, with their 95% confidence intervals (CI) across population outcomes. We performed subgroup analyses among the six World Health Organization (WHO) regions (Africa [AFR], Region of the Americas [AMR], South-East Asia Region [SEAR], European Region [EUR], Eastern Mediterranean Region [EMR], and the Western Pacific Region [WPR]), as well as among select population subgroups.

Results

Of the 2531 studies screened, 61 studies, with a cumulative sample size of 263,857 participants from 87 countries were eligible for inclusion. The overall vaccine acceptance and uptake rates were 59.7% and 30.9% globally. Acceptance and uptake rates among the LGBTQI+ community were 73.6% vs 39.8% globally, 60.9% vs. 37.1% in AMR, 80.9% vs. 50.0% in EUR, and 75.2% vs. 33.5% in WPR. Among PLHIV, vaccine acceptance and uptake rates were 66.4% vs. 35.7% globally, 64.0% vs. 33.9% in AMR, 65.1% vs. 27.0% in EUR, and 69.5% vs. 46.6% in WPR. Among healthcare workers, vaccination intention was 51.0% globally.

Conclusions

Tailored interventions are needed to bolster confidence in the mpox vaccine, maximize vaccine uptake, and increase vaccine access to close the gaps between acceptance and uptake especially among key populations residing in regions with low rates of acceptance and uptake.
Harnessing acetogenic bacteria for one-carbon valorization toward sustainable chemical production
Authors: Bae Jiyun , Park Chanho , Jung Hyunwoo , Jin Sangrak , Cho Byung-Kwan
Published: July 2024

This review discusses the potential of harnessing acetogenic bacteria for one-carbon valorization as a sustainable chemical production platform, comprehensively covering current challenges, recent progress, and emerging trends in this field.
A toolbox for enzymatic modification of nucleic acids with photosensitizers for photodynamic therapy
Authors: Niogret Germain , Chériaux Camille , Bonhomme Frédéric , Levi-Acobas Fabienne , Figliola Carlotta , Ulrich Gilles , Gasser Gilles , Hollenstein Marcel
Published: July 2024

Enzymatic bioconjugation of DNA with efficient photosensitizers for photodynamic therapy applications.
Miltefosine impacts small molecule transport in Gram-positive bacteria
Authors: Blake Marea J. , Page Eleanor F. , Smith Madeline E. , Calhoun Tessa R.
Published: July 2024

Second harmonic scattering reveals differences in how the drug, miltefosine, impacts small molecule transport through the membranes of living bacteria. Large scale changes to membrane order, however, are not observed suggesting localized effects.
Singlet oxygen is an emissive ligand
Authors: Asselin Paul , Schlachter Adrien , Harvey Pierre D.
Published: July 2024

Experimental evidence of the existence of a ZnTPP–O2 complex following photosensitization at the solid–gas interface is presented, confirming prior hypotheses.
Sustainable production and applications of metal–organic frameworks
Authors: Chu Hongyu , Liu Zhengxing , Wang Chong-Chen , Wang Peng
Published: July 2024

Recent years have witnessed encouraging progress in the sustainable production and reuse of metal–organic frameworks in the liquid phase. These advances have driven the construction of a blue (recycling) MOF economy and ecological chains.
An initiator loaded separator triggering in situ polymerization of a poly(1,3-dioxolane) quasi-solid electrolyte for lithium metal batteries
Authors: Huang Hao , Wei Chaohui , Zhao Qiang , Zhou Aijun , Li Jingze
Published: July 2024

Aluminum trifluoromethanesulfonate (Al(OTf)3) is preloaded on a separator sheet as the initiator to trigger the ring-opening reaction of 1,3-dioxolane (DOL), leading to a higher crystallization degree for polymer matrix near the separator.
Improving the performance of kesterite solar cells by solution germanium alloying
Authors: Xiang Sitong , Li Yize , Xiang Chunxu , Liu Hongkun , Zheng Yuanyuan , Wang Shaoying , Yan Weibo , Xin Hao
Published: July 2024

Cation substitution is an effective strategy to regulate the defects/electronic properties of kesterite Cu2ZnSn(S,Se)4 (CZTSSe) absorbers and improve the device photovoltaic performance.
Efficient recovery of gold from solution with a thiocyanate-modified Zr-MOF: adsorption properties and DFT calculations
Authors: Xie Yu-juan , Li Tang-ming , Shang Zhao-ting , Lu Wang-ting , Yu Fan
Published: July 2024

UiO-66-NCS exhibited good adsorption capacity (675.5 mg g−1) and exceptional selectivity. Adsorption kinetics and isotherms demonstrated the pseudo-second-order adsorption scheme and a Langmuir-type procedure by the adsorption of Au(iii).
Enhanced removal of perfluorooctanoic acid by VUV/sulfite/iodide: efficiencies, influencing factors, and decomposition mechanism
Authors: Liu Hong , Jia Ruibao , Xin Xiaodong , Guo Weilin , Li Wei , Wang Mingquan , Sun Shaohua
Published: July 2024

Perfluoroalkyl acids (PFAAs) such as perfluorooctanoic acid (PFOA) have been referred to as “forever chemicals” and are toxic and bioaccumulative.
Vitrimerization of crosslinked poly(ethylene-vinyl acetate): the effect of catalysts
Authors: Jamei Oskouei Amin , Mao Erqian , Gray Thomas G. , Bandegi Alireza , Mitchell Sarah , Sing Michelle K. , Kennedy Jayme , Miller McLoughlin Kimberly , Manas-Zloczower Ica
Published: July 2024

DFT calculations and experiments with four zinc salts as transesterification catalysts show discrepancies between computational and experimental flow activation energies, highlighting the importance of catalyst thermal stability and molecular size.
Insight into mechanism for remarkable photocatalytic hydrogen evolution of Cu/Pr dual atom co-modified TiO2
Authors: Zheng Hongshun , Zi Baoye , Zhou Tong , Qiu Guoyang , Luo Zhongge , Lu Qingjie , Santiago Alain Rafael Puente , Zhang Yumin , Zhao Jianhong , Zhang Jin , He Tianwei , Liu Qingju
Published: July 2024

The photocatalytic hydrogen production activity was significantly enhanced by the synergistic interaction between Cu single atoms and Pr atoms.
Design of substituted tetrahydrofuran derivatives for HIV-1 protease inhibitors: synthesis, biological evaluation, and X-ray structural studies
Authors: Ghosh Arun K. , Lee Daniel , Sharma Ashish , Johnson Megan E. , Ghosh Ajay K. , Wang Yuan-Fang , Agniswamy Johnson , Amano Masayuki , Hattori Shin-ichiro , Weber Irene T. , Mitsuya Hiroaki
Published: July 2024

A series of potent HIV-1 protease inhibitors with novel P2-ligands have been designed, synthesized and evaluated.
A persistent radical anion naphthalenediimide-based hybrid material for near-infrared photothermal conversion and photocatalytic oxidative organic transformations
Authors: Dai Weijun , He Chixian , Li Sirui , Xu Yuanrong , Cheng Feixiang , Liu Jian-Jun
Published: July 2024

A naphthalenediimide-based hybrid material was designed and prepared, which exhibits NIR photothermal conversion and promotes the photocatalytic hydroxylation of arylboronic acids and C-3 thiocyanation of indoles.
Coordination catalysis of metals and polydopamine enables controlled release of CO from MnCO by enhancing oxidative stress and the thermal effect
Authors: Zhang Wen-Xin , Li Lin-Yu , Shu Yang , Wang Jian-Hua
Published: July 2024

Coordination catalysis of Zn/Mn and polydopamine enhanced intracellular oxidative stress and thermal effect, and thus facilitated release of CO from MnCO.
Au depositing and Mg doping synergistically regulates an In2O3 photocatalyst for promoting CO2 reduction and CH4 exclusive generation
Authors: Liu Yanduo , Li Jiadong , Dong Xianglan , Dai Lina , Zhang Enqi
Published: July 2024

Mg–Au bimetallic functional sites modified In2O3 nanoflowers hybrid photocatalysts with exceptional activities are successfully fabricated, attributed to the enhanced CO2 adsorption and activation ability and optimized band gap structure.
Unexpected in crystallo reactivity of the potential drug bis(maltolato)oxidovanadium(iv) with lysozyme
Authors: Paolillo Maddalena , Ferraro Giarita , Cipollone Irene , Garribba Eugenio , Monti Maria , Merlino Antonello
Published: July 2024

The structure of the adduct formed by lysozyme with bis(maltolato)oxovanadium(iv) within crystals grown in NaCl and Na-acetate at pH 4.0 reveals an unexpected reaction product.
Na0.4MnO2/MXene nanocomposites as cathodes for high-performance aqueous zinc-ion batteries
Authors: Si Guangquan , Li Wei , Li Taijiang , Wang Caixia , Sun Qi
Published: July 2024

Na0.4MnO2@MXene is employed as a cathode material in zinc-ion batteries, exhibiting enhanced diffusion kinetics, high capacity, and excellent cycling stability.
Experimental study on the leaching effect of different chelating agents on the constant metal ions of lignite
Authors: Chen Dawei , Xie Jun , Zhang Jingyi , Wang Yi , Wang Faquan
Published: July 2024

Based on the leaching concentration of CMIs from ICP experiments, the ASDA chelating agent for lignite was optimized from four chelating agents. The CMIs leaching effect was characterized and analyzed using contact angle, SEM, and BET measurements.
Sustainable food packaging using modified kombucha-derived bacterial cellulose nanofillers in biodegradable polymers
Authors: Koreshkov Mikhail , Takatsuna Yuuki , Bismarck Alexander , Fritz Ines , Reimhult Erik , Zirbs Ronald
Published: July 2024

The incorporation of modified bacterial cellulose derived from agricultural waste improves biodegradable composites by reducing oxygen permeability and accelerating biodegradation while maintaining mechanical properties.
Recent progress in non-lithium rechargeable batteries with micro to macro 3D engineered electrode architecture
Authors: Parida Anita , Giri Soumen
Published: July 2024

This review article contains a comprehensive and critical discussion of non-lithium 3D printed batteries from macro to micro scale.
An ultralow-concentration (0.05 M) electrolyte for advanced K-ion batteries
Authors: Zhu Guo-Yu , Yang Guo-Zhan , Huang Bai-Hua , Wang Bo , Ye Xue-Bin , Zheng Ze-Lin , Feng Bao-Qi , Zeng Xian , Bin De-Shan , Liu Lin , Li Dan
Published: July 2024

An ultralow-concentration (0.05 M) KFSI-based electrolyte can serve as the electrolyte for K-ion batteries, offering low cost, low viscosity, reduced corrosion risk, and impressive electrochemical performances over a wide range of temperatures.
Upcycling plastic wastes into high-performance nano-MOFs by efficient neutral hydrolysis for water adsorption and photocatalysis
Authors: Yun Ling-Xia , Qiao Meng , Zhang Bin , Zhang Hang-Tian , Wang Jie-Xin
Published: July 2024

Employing polyethylene terephthalate (PET) wastes as a linker source is a cost-effective, renewable, and sustainable approach to attain high-performance nano-MOFs for water adsorption and photocatalysis.
Adipocyte-targeted celastrol delivery via biguanide-modified micelles improves treatment of obesity in DIO mice
Authors: Ouyang Hongling , Zhang Yunxiao , Zhu Yueting , Gong Tao , Zhang Zhirong , Fu Yao
Published: July 2024

Following intravenous administration, MET-CS-PBE@CLT micelles actively distribute to the adipose tissue via CD44-mediated targeting. The presence of biguanide groups ensure adipocyte targeting via plasma membrane monoamine transporters.
Intravenous injectable metformin-Cu(ii)-EGCG coordination polymer nanoparticles for electrothermally enhanced dual-drug synergistic tumor therapy
Authors: Di Jingran , Huang Chenqi , Zhao Chenyu , Luo Siyuan , Wang Rong , Zhang Shuai , Zhu Hongrui , Wu Daocheng
Published: July 2024

We developed intravenous injectable metformin-Cu(ii)-EGCG coordination polymer nanoparticles for efficient tumor synergistic therapy in conjunction with the micro-electrothermal needle.
Mechanisms of inclusion of thallium-201 into Prussian blue nanoparticles for nuclear medicine applications
Authors: Wulfmeier Katarzyna M. , Blower Philip J. , Fajardo Galo Paez , Huband Steven , de Rosales Rafael T. M. , Walker David , Terry Samantha YA , Abbate Vincenzo , Pellico Juan
Published: July 2024

Prussian blue nanoparticles are radiolabelled with Tl-201 and characterised to provide the unambiguous confirmation of the inclusion mechanism.
Band alignment of TiO2 by controling Cl content for high-efficiency perovskite solar cells
Authors: Ji Long , Zhang Ting , Li Shibin
Published: July 2024

By optimizing the growth time of the TiO2 electron transport layer, the perovskite cell device prepared by TiO2 with a low interface defect and optimal bandgap matching achieved the highest conversion efficiency of 24.31%.
High-quality indium–gallium–zinc oxide films synthesized by atomic layer deposition using a single cocktail precursor based on a liquid-delivery system and their application in transistors and inverters
Authors: Park Sang-Joon , Park Se-Ryong , Jeon Woo-Seok , Na Jong Mu , Lim Jun Hyung , Ham Sukhun , Chung Yung-Bin , Ha Tae-Jun
Published: July 2024

High-quality indium–gallium–zinc oxide (IGZO) films synthesized by atomic layer deposition (ALD) using a single cocktail precursor based on a liquid-delivery system are demonstrated for the first time.
Piezo-phototronic effect modulated performances of guest-substrate integrated p–i–n GaN ultraviolet detectors
Authors: Li Peishan , Yang Yuqing , Dong ZeXin , Huang Xiaoyue , Wang Yihan , Chang Huan , Song Zihao , Peng Zhenjian , Zhang Kang , Wang Xingfu
Published: July 2024

High quality freestanding p–i–n GaN UV photodiodes were successfully fabricated on flexible mica by using selective electrochemical (EC) etching and an In–Au (50 nm/50 nm) bonding layer, which is convenient and the thermal damage is low.
Mesh‐free Monte Carlo method for electrostatic problems with floating potentials
Authors: Yin Wenjing , Wang Yunqing , Deng Hong , Wang Jiawei , Gao Xiaoke , Huang Ruoyu , He Kun , Chen Weijiang , Dong Tianyu
Published: July 2024

Numerical simulation plays a crucial role in the analysis and design of power equipment, such as lightning protection devices, which may become inefficient using traditional grid‐based methods when handling complex geometries of large problems. The authors propose a grid‐free Monte Carlo method to handle electrostatic problems of complex geometry for both the interior and exterior domains, which is governed by the Poisson equation with a floating potential boundary condition that is neither a pure Dirichlet nor a Neumann condition. The potential and gradient at any given point can be expressed in terms of integral equations, which can be estimated recursively within the walk‐on‐sphere algorithm. Numerical examples have been demonstrated, including the evaluation of the mutual capacitance matrix of multi‐conductor structures and lighting striking near real fractal trees. The proposed method shows advantages in terms of geometric flexibility and robustness, output sensitivity, and parallelism, which may become a candidate for game‐changing numerical methods and exhibit great potential applications in high‐voltage engineering.
A domain adaptation‐based convolutional neural network incorporating data augmentation for power system dynamic security assessment
Authors: Azad Sasan , Ameli Mohammad Taghi
Published: July 2024

Recently, deep learning (DL) based dynamic security assessment (DSA) methods have been very successful. However, although a DSA model can be trained well for a specific topology, it often does not perform well for other topologies. Since the topology in real‐world power systems is frequently changing, the performance reduction of DL‐based DSA methods is very serious, which is a challenging and urgent problem. This paper proposes a novel DSA method based on a convolutional neural network (CNN) to solve this problem. In the proposed method, a strong yet simple domain adaptation approach named adaptive batch normalization (AdaBN) is used, which significantly enhances the extensibility and generalizability of the DSA model when the topology changes and eliminates the need to train a large number of models. This approach achieves a deep adaptation effect by modulating the statistics from the source domain to the target domain in all batch normalization layers across the model. Unlike other domain adaptation methods, this method is parameter‐free, requires no additional components, and has advanced performance despite its simplicity. In addition, this paper introduces TGAN‐based data augmentation to deal with the difficulty of costly data collection and labelling. This data augmentation makes the proposed model applicable to small databases. The test results of the proposed method on IEEE 39‐bus and IEEE 118‐bus systems show that this method can evaluate system dynamic security during topology changes and in the face of data noise with high accuracy.
Liebe Leser*innen der Adipositas,
Authors: Wabitsch Martin , Brandt-Heunemann Stephanie
Published: July 2024

Die Versorgung von Kindern und Jugendlichen mit Adipositas erfordert eine
multidisziplinäre und ganzheitliche Herangehensweise. Nur durch gemeinsame
Anstrengungen auf verschiedenen Ebenen – von der Community-Medizin über
strukturierte und leitliniengerechte ambulante Versorgungsmöglichkeiten bis hin zur
spezialisierten Betreuung in Hochschulambulanzen und Rehazentren - können wir
sicherstellen, dass Kinder und Jugendliche mit Adipositas und deren Familien die
Unterstützung erhalten, die sie benötigen.
Antwort auf den Leserbrief zum Beitrag „Die Energiebilanz
charakterisiert Adipositas, sie erklärt sie aber nicht und sie ermöglicht keine
Strategien für eine nachhaltige Behandlung“
Authors: Bosy-Westphal Anja , Müller Manfred J
Published: July 2024

Wir danken Herrn Wirth für seine kritischen Anmerkungen zu unserem Artikel. Die
Diskussion hilft uns, Missverständnisse zu vermeiden und gibt uns Gelegenheit,
unseren Standpunkt deutlicher zu erklären.
Bedeutung der stationären Rehabilitation von Kindern und Jugendlichen
mit Adipositas
Authors: Gellhaus Ines , Prinz Nicole , Neugebauer Friederike , Stachow Rainer , Falkenberg Christian , Gerber Doris , Heber Kirstin , Heß Juliane , Pellarin-Schlingensiepen Maike , Puch-Kapst Kathrin , Schiel Ralf , Schmelzle Hansjörg , Schmiederer Gerda , Volmer-Berthele Nora , W. Holl Reinhard
Published: July 2024

Diese Arbeit stellt die spezifischen Daten aus der
Adipositas-Patienten-Verlaufsdokumentation (APV) von Kindern und Jugendlichen
mit Adipositas, die in stationären Rehabilitationskliniken behandelt werden, in
den Gesamtzusammenhang der vorliegenden Statistiken der Deutschen
Rentenversicherung (DRV). Die stationäre Rehabilitation spielt sowohl
quantitativ als auch qualitativ eine wichtige Rolle in der multiprofessionellen
Versorgung von Kindern und Jugendlichen mit Adipositas. Sie gehört in den
Kontext einer lebenslangen Behandlungskette von (noch auszubauenden) ambulanten
uni- oder multimodalen Angeboten und Nachsorgen für die chronische Erkrankung
Adipositas.
Tumoröse Kalzinose – Morbus Teutschländer – am Ringfingergrundgelenk
Authors: Waltenspül Claudia , Spies Christian Karl , Janzen Jan
Published: July 2024

Eine 51-jährige Patientin präsentierte sich mit einer druckdolenten Schwellung palmar über dem Metakarpophalangealgelenk des Ringfingers. Konventionell radiologisch und kernspintomografisch zeigte sich eine einzelne abgerundete Raumforderung. Nach operativer Exzision und histologischer Aufarbeitung erfolgte die Diagnosestellung der seltenen tumorösen Kalzinose (Synonym: Morbus Teutschländer).
Flow Diversion for the Treatment of Middle Cerebral Artery Aneurysms
Authors: Schüngel Marie-Sophie , Wohlgemuth Walter A , Elolf Erck , Rensch Leonhard , Brill Richard , Schob Stefan
Published: July 2024

The invention of flow diverting stents (FDS) is a novel milestone in the field of endovascular aneurysm therapy, promoting physiological healing of the vessel segment contrary to prior deconstructive treatment strategies, such as coiling. The effects of FDS are based on changes in flow patterns, segmental wall stabilization, and the growth of a neointima. Although flow diversion is already well established for cerebral aneurysms in proximal segments, peripheral locations remain challenging. Especially the middle cerebral artery (MCA) with its predominance of non-collateralized perforators and functional end arteries that supply the eloquent areas of the brain is of major concern.

The literature was reviewed for flow diversion of the MCA and antiplatelet therapy.

Resulting from the special anatomical characteristics of the MCA, FDS implantation in this territory is completely different from the proximal vessel segments. Still, flow diversion represents an effective endovascular strategy, especially in otherwise non-accessible or sufficiently treatable lesions. However, the risk of ischemic adverse events might be increased. Special attention to the individual decision regarding device selection, antiplatelet regimen, and exact definition of the proximal and distal landing zone considering the jailed side branches is essential for a good angiographic and clinical outcome.
Historical Perspective of Homeopathy in the Brazilian Public Health System
Authors: da Costa Fujino Fernanda Maria Simões , de Eston Armond Jane , Ribeiro Ana Paula , de Souza Patrícia Colombo
Published: July 2024

Homeopathy was introduced in Brazil with the French doctor Benoît Jules Mure's arrival in 1840 and was officially recognised in 1980 as a medical specialty by Brazilian regulatory authorities. Public health policies played an important role in incorporating homeopathy into the Brazilian Unified Health System (SUS), emphasising homeopathy's coherence with SUS's fundamental principles and with other national health policies. Homeopathy is supported by the guidelines of the National Primary Health Care Policy and the National Policy on Integrative and Complementary Practices, and its offer in the SUS has been recognised since 2006. Challenges persist, however, such as the low prevalence of the use of homeopathy, lack of investment in professional training and under-reporting of homeopathy outpatient appointments. Investments in disseminating information on homeopathic philosophy and raising awareness among managers and health professionals are essential to strengthen its presence in the Brazilian public health system.
Comparação de métodos bidimensionais manuais e tridimensionais automatizados de avaliação da morfologia da articulação do ombro por imagens de tomografia computadorizada
Authors: Rocha Motta Filho Geraldo da , Amaral Marcus Vinícius , Cohen Márcio , Carvalho Marcio Schiefer de Sá , Fonseca Raphael Soares da , Oliveira Ana Carolina Leal de
Published: July 2024

Objetivo Avaliar a concordância interobservador na medida dos parâmetros anatômicos do ombro utilizando métodos manuais de tomografia computadorizada (TC) bidimensional (2D) não formatada no plano da escápula e compará-los à medida automatizada obtida com o programa Blueprint (Wright Medical, Memphis, TN, Estados Unidos), que utiliza imagens tridimensionais (3D) reconstruídas.

Métodos Este é um estudo transversal com a utilização de imagens de TC 2D de 38 pacientes com diferentes diagnósticos. Os parâmetros anatômicos foram medidos por métodos manuais - versão, método de Friedman et al., e método do vault; inclinação, por método de Maurer et al., e subluxação do ombro segundo Walch et al. As mensurações foram realizadas por cinco cirurgiões qualificados e independentes, e comparados aos parâmetros obtidos pelo programa automatizado Blueprint.

Resultados Foram observadas diferenças significativas entre a versão de medida manual obtida pelo método de Friedman et al. e a versão automatizada. Os valores médios de inclinação não apresentaram diferenças estatisticamente significativas entre os métodos. A média observada de subluxação teve diferenças significativas entre as análises realizadas pelo método automatizado e pelos cirurgiões.

Conclusão As medidas manuais de versão e inclinação da glenoide realizadas por cirurgiões experientes são eficazes, e o método da abóbada é superior ao de Friedman et al. na análise de deformidades glenoidais graves.