bluuebunny/crossref_metadata_2025 huggingface dataset:
Stoichiometry and architecture of the platelet membrane complex glycoprotein Ib-IX-V
Authors: Lu Juanjuan , Zhang Chunli , Shi Shaohua , Li Shaobai , Liu Junling , Wu Jian , Huang Chenhui , Lei Ming
Published: March 2023

Glycoprotein (GP) Ib-IX-V is the second most abundant platelet receptor for thrombin and other ligands crucial for hemostasis and thrombosis. Its activity is involved in platelet adhesion to vascular injury sites and thrombin-induced platelet aggregation. GPIb-IX-V is a heteromeric complex composed of four subunits, GPIbα, GPIbβ, GPV and GPIX, in a stoichiometric ratio that has been wildly debated. Despite its important physiological roles, the overall structure and molecular arrangement of GPIb-IX-V are not yet fully understood. Here, we purify stable and functional human GPIb-IX-V complex from reconstituted EXPi293F cells in high homogeneity, and perform biochemical and structural characterization of this complex. Single-particle cryo-electron microscopy structure of GPIb-IX-V is determined at ∼11 Å resolution, which unveils the architecture of GPIb-IX-V and its subunit organization. Size-exclusion chromatography-multi-angle static light scattering analysis reveals that GPIb-IX-V contains GPIb-IX and GPV at a 1:1 stoichiometric ratio and surface plasmon resonance assays show that association of GPV leads to slow kinetics of thrombin binding to GPIb-IX-V. Taken together, our results provide the first three-dimensional architecture of the intact GPIb-IX-V complex, which extends our understanding of the structure and functional mechanism of this complex in hemostasis and thrombosis.
Peripheral arterial disease among children with type 1 diabetes mellitus in a Nigerian teaching hospital
Authors: Akinyosoye Gbenga , Akinola Ibironke Jadesola , Lamina Amotunur Bukola , Akinsola Clement Morakinyo
Published: March 2023

Objectives

The study aimed to determine the prevalence of PAD in children with T1DM and to correlate PAD with clinical characteristics in children with T1DM.

Methods

A comparative cross-sectional study was conducted involving 90 subjects (forty-five with T1DM and 45 apparently healthy comparative subjects that were matched for age and gender). Systolic blood pressure was measured in all limbs using the pocket Doppler machine (Norton Doppler scan machine). Ankle brachial index (ABI) was calculated as a ratio of ankle to arm systolic blood pressure. Peripheral arterial disease was defined as ABI less than 0.9.

Results

The prevalence of PAD was significantly higher in children with T1DM than in the matched comparison group (37.8% vs. 6.7%, p<0.001). Average values of waist circumference, hip circumference, weight, height and body mass index were comparable in subjects with TIDM and the comparison group (p>0.05). Subjects with PAD had a poorer glucose control evident by higher average values of glycated haemoglobin than those without PAD (13.47 ± 3.2% vs. 8.16 ± 2.3%, p<0.001). There is a strong negative correlation between ABI scores and glycated haemoglobin among subjects with T1DM (r=−0.626, p<0.001).

Conclusions

With these findings, it is recommended that screening for PAD in children who have T1DM and poor glycaemic control should be done early to prevent cardiovascular complications before they arise.
The Nasal Solitary Chemosensory Cell Signaling Pathway Triggers Mouse Avoidance Behavior to Inhaled Nebulized Irritants
Authors: Xi Ranhui , McLaughlin Sean , Salcedo Ernesto , Tizzano Marco
Published: March 2023

The nasal epithelium houses a population of solitary chemosensory cells (SCCs). SCCs express bitter taste receptors and taste transduction signaling components and are innervated by peptidergic trigeminal polymodal nociceptive nerve fibers. Thus, nasal SCCs respond to bitter compounds, including bacterial metabolites, and these reactions evoke protective respiratory reflexes and innate immune and inflammatory responses. We tested whether SCCs are implicated in aversive behavior to specific inhaled nebulized irritants using a custom-built dual-chamber forced-choice device. The behavior of mice was recorded and analyzed for the time spent in each chamber. Wild-type (WT) mice exhibited an aversion to 10 mmdenatonium benzoate (Den) or cycloheximide and spent more time in the control (saline) chamber. The SCC-pathway knock-out (KO) mice did not exhibit such an aversion response. The bitter avoidance behavior of WT mice was positively correlated with the concentration increase of Den and the number of exposures. Bitter-ageusic P2X2/3 double KO mice similarly showed an avoidance response to nebulized Den, excluding the taste system’s involvement and pointing to an SCC-mediated major contributor to the aversive response. Interestingly, SCC-pathway KO mice showed an attraction to higher Den concentrations; however, chemical ablation of the olfactory epithelium eliminated this attraction attributed to the smell of Den. These results demonstrate that activation of SCCs leads to a rapid aversive response to certain classes of irritants with olfaction, but not gustation, contributing to the avoidance behavior during subsequent irritant exposures. This SCC-mediated avoidance behavior represents an important defense mechanism against the inhalation of noxious chemicals.
“Competitive Rent-Seeking” in the Kim Jong Un Era of North Korea
Authors: Jung Suehyun
Published: March 2023

This article presents the “Competitive Rent-Seeking Model” that accounts for how reform policies paved the way for sustainable economic growth in “authoritarian transition economies” despite widespread corruption. Competitive rent-seeking refers to the process whereby the entry barrier to rent-generating economic activities, once monopolized by a small number of vested interests, has been lowered inviting more potential rent-seekers into the system. This was accomplished by enacting decentralizing and market-friendly reform policies that in turn exacerbated corruption but boosted production efficiency leading to improved social welfare. The model is exemplified by the Chinese and Vietnamese experiences during the 1980s. Furthermore, this article demonstrates that the model is applicable to the North Korean economy under Kim Jong Un’s economic reform policy of the “Socialist System of Responsible Business Operation in Economic Management” initiated in 2014.
Legal Regulation of Remote Work in Slovakia and the Covid-19 Pandemic
Authors:   Faculty of Law, University of Trnava, Slovakia, Bulla Martin
Published: March 2023

This paper aims to examine the development of the legal regulation of remote working arrangements in Slovak labour law and to determine the main legal issues that keep thistype of work from being more widely utilised in practice. To this end, the article analyses the applicable provisions of the Slovak Labour code, as they developed throughout the years, in particular the changes implemented in connection with the Covid-19npandemic. It also investigates other applicable sources of law, as well as case law and relevant literature. The main issues identified by the article that need to be addressed by the legislator, involve three areas: (i.) formulation of the place of work in the employment agreement, (ii.) working time and rest periods of remote workers and (iii.) the range of supervisory powers of the employer vis-à-vis remote workers. The author argues that the legislator ought to create more favourable and clear legal conditions for remote work and to enable this type of work to be performed under all contractual types recognised by Slovak labour law, not just in the (standard) employment relationship.
Multifunctional water-soluble polymeric fluorescent whitening agents based on 4,4'-bis (1,3,5-triazinyl)- diamino stilbene-2,2'-disulfonic acid structure
Authors: Guo Mingyuan , Zhang Guanghua , Du Lun , Zheng Hua , Liu Guojun , Li Yundan
Published: March 2023

A series of multifunctional water-soluble polymeric fluorescent whitening agents (PFWAs, 5a-f) based on 4,4′-diamino-stilbene-2,2′-disulfonic acid (DSD acid)-triazine structure were successfully synthesized using a nucleophilic substitution reaction with cyanuric chloride, DSD acid, amino compounds, polyethylene glycol (PEG), and/or polyvinyl alcohol (PVA) as raw materials. The structure of the PFWAs was characterized by FT-IR, and the substitution degree was calculated from the results of an elemental analysis. The optical properties of the PFWAs were measured by the UV-vis spectra and fluorescence spectra when the PFWAs were applied to paper fiber to serve the roles of light stabilizer, fluorescent whitener, and surface-sizing agent. Then the performance of the PFWAs on paper was evaluated by measuring the surface strength and smoothness of paper, brightness degree of paper, and the yellowness value (value of PC) of paper. The results indicated that the PFWAs had better light stability in water solution than that of a conventional fluorescent whitening agent (FWA) as a light stabilizer. According to the surface-sizing experiment and UV aging experiment, it was concluded that not only could the PFWAs enhance the surface strength and smoothness of paper, but also have a better effect on anti-UV aging than that of FWA as a light stabilizer and fluorescent whitener agent.
Experiment and numerical modeling of stratified downdraft gasification using rice husk and wood pellet
Authors: Wasinarom Kittipass , Charoensuk Jarruwat
Published: March 2023

Stratified downdraft gasification using rice husks and wood pellets was carried out under different air mass flow rates using both experimental and numerical methods. The flame propagation rate was calculated from the temperature profile at different time steps and was used as the prerequisite to calculate the equivalent ratio in modeling the combustion zone. Chemical equilibrium modeling was employed to predict the temperature and composition of the sample in the combustion zone. Finite kinetic modeling was used to simulate the reduction zone. The initial temperature and composition of the reduction zone simulation were obtained from the chemical equilibrium results taken from the combustion zone. The flame propagation speed of the rice husk was found to be around five times greater than wood pellet at the same air flow rate. The peak temperature of both fuels had similar values. For all air mass flow rates, the equilibrium modeling over-estimated the peaks in comparison with the experimental tests. The kinetic model was sensitive to the input temperature at the zone inlet. The predicted temperature in the reduction zone demonstrated high kinetic activity at the top of the zone due to a high gas temperature. The predicted temperature was in agreement with the experimental test results.
Pulping of bamboo using supercritical ammonia with recovery and reuse of the ammonia
Authors: Zhang Yidong , Zhang Xihui , Chi Shanshan , Li Zhenqiu
Published: March 2023

Preliminary research on supercritical ammonia pulping of bamboo was completed using a differential thermal analyzer, scanning electron microscope, X-ray diffractometer, and an energy spectrometer. The results showed that ammonia can be recovered from bamboo raw materials under the supercritical condition of 185 to 190 °C. Compared with conventional kraft bamboo pulp, the separated bamboo pulp met the pulp quality requirements of industrial paper, achieving high efficiency and a multi-level utilization of biomass resources. Ammonia in the system can be recycled.
Technologies for Halide Removal in Water Treatment – A State-of-the-Art Review
Authors: Nariyan Elham , Yu Qiming Jimmy , Hamilton David , Li Qin
Published: March 2023

Halides (X=Cl, Br, I) are naturally present in water, and halide concentrations can be high in water sources that are impacted by high salinity. Halides are also present in wastewater streams from various industrial operations such as pulp and paper, oil and gas, and mining. Drinking water guideline limits have been established for halides, and halide removal from water is important in several ways. Chloride concentration in water is more related to salinity, and its removal from water matters because of adverse health effects, water scarcity, corrosion, and industrial needs. In drinking water treatment, disinfection is essential to improve water quality and prevent the spread of water born pathogens. However, disinfectants also produce harmful disinfection by-products (DBPs) from precursors such as halides and natural organic matter (NOM) in the source water. Removing halides in the source water before disinfection is a preferred option to increase the disinfection efficiency and avoid forming more toxic DBPs. Some industrial-made isotopes are radioactive and carcinogenic, and iodide produces iodinated DBPs. Bromide removal is important because it produces brominated DBPs. Halides also affect AOPs and can cause more active radicals such as OH. and SO4-. to transform into less active radicals. This paper aims to comprehensively review the sources of halides, the chemistry, and interaction in forming DBPs, current regulatory limits and state-of-art removal technologies available, and their challenges.
Changes in Counter Movement Jump Height, Take-off Force and Maximum Concentric Power of Collegiate Athletes After Two Sessions Per Week Plyometric Training on Different Training Surfaces
Authors: Borah Poli , Gogoi Lakshyajit , Gogoi Hemantajit , Govindasamy Karuppasamy , Prasad Sambhu , Minu Tadang , Parpa Koulla , Ben Abderrahman Abderraouf
Published: March 2023

Purpose: This study aimed to examine the effects of two sessions per week plyometric training on different surfaces on the counter movement jump height, take-off force, and maximum concentric power of collegiate athletes.

Material and methods: Male collegiate athletes (n=24, age=18.46±1.14 years, weight=64.88±5.61 kg and height=1.72±0.07 metres)) from a physical training centre were randomly and equally assigned to three groups, each trained on different surfaces (synthetic, cinder and sand). The training intervention was implemented twice a week and lasted for 8 weeks. The athletes were tested before and after the intervention to assess changes in the performance of counter movement jump height (CMJHT), take-off force (CMJTOF) and maximum concentric power (CMJMCP).

Results: Results showed that overall measurement of CMJHT, CMJTOF and CMJMCP improved significantly (p≤0.05, Δ %=10.50; p≤0.05, Δ%=11.11; p≤0.05, Δ%=11.41). However, training surfaces have no significant effect on the improvement of the selected variables (CMJHT:F(2,21)=2.37, p=0.118, ηp2=0.184; CMJTOF:F(2,21)=1.28, p=0.299, ηp2=0.109; CMJMCP:F(2,21)=0.061, p=0.941, ηp2=0.006). Further, for the synthetic track surface group CMJHT, CMJTOF and CMJMCP improved significantly (p≤0.05, Δ%=16.36; p≤0.05, Δ%=17.50; p≤0.05, Δ%=17.99); for the cinder track surface group CMJHT and CMJMCP improved significantly (p≤0.05, Δ%=9.15; p≤0.05, Δ%=10.33) and for the sand surface group only CMJHT improved significantly (p≤0.05, Δ%=5.68).

Conclusions: The findings suggest that plyometric training on different surfaces can effectively improve athletic performance, but the specific surface type does not appear to impact the outcomes significantly. The study further suggested analysing the injury risk associated with plyometric training on various training surfaces and discovering the optimal training surface for minimising injury risk while maximising performance gains.
Revisiting the partition of a set of numerical variables through a mixture of Watson distribution on the n-sphere and underlying factor analysis model
Authors: Gomes Paulo
Published: March 2023

A key step of any statistical multivariate analysis concerns the choice of variables in line with the main objectives of the study. Usually, the available procedures to face this problem are restricted to a-posteriori statistical analysis, using Bayesian approaches or stepwise selection procedures. The main objective of the present paper is to revisit a framework where the a-priori choice of variables makes sense under specific conditions and to propose a factor analysis model particularly adapted to structured quantitative big data. We have associated our complete sample of variables to a mixture of two bipolar Watson distributions defined on the n-sphere, W ( μ i , ξ i ) , i = 1 , 2 , where μ i is a direction parameter and ξ i is a concentration parameter. The likelihood estimates of the direction parameter μ i is just the first principal component associated of a PCA of cluster i. The identification of the mixture of Watson distribution was obtained by cluster analysis, namely a previous hierarchical cluster analysis followed by a k-means partition of the global sample of variables. These multivariate data were explained by an alternative factor analysis model potentially delivering directly interpretable solutions without the need of rotations procedures. The loadings of this factorial model were obtained by regression. The final results concerning communalities of the 16 variables showed that for a great part of them unit variance was quite well explained by the factorial model.
Can vitamin D positively impact one or more postacute-COVID-19 syndrome musculoskeletal and cognitive complications?
Authors: Marks Ray
Published: March 2023

The coronavirus disease known as COVID-19 has persisted in various forms now for three years without any major reduction on its detrimental health outcomes. This mini review highlights some aspects of the condition now known as the post-acute or long COVID-19 syndrome that has recently been seen to emerge among a fair percentage of COVID-19 survivors. It asks whether efforts to ensure vitamin D intake or exposure levels can impact one or more manifestations of the post-acute COVID-19 syndrome in some way. Using the key words: Vitamin D, Long COVID or Post-acute COVID-19 the PUBMED, PubMed Central, and Google Scholar were explored for articles of relevance. Described in narrative form, these data reveal that while this topic has not yet been articulated to any degree in most management articles as of December 2022, the challenges to musculoskeletal health alone of post-acute COVID-19 appear to warrant its due consideration.
Prevalence of behavioral risk factors and their association with dementia in the urban population of North India
Authors: Singh Ram B , Wilczynska Agnieszka , Fedacko Jan , Horiuchi Rie , Takahashi Toru , Fatima Ghizal , Ismail MA Manal , Magomedova Aminat
Published: March 2023

Background: Dementia has become a public health problems due to its association with behavioural risk factors; smoking, alcoholism, sedentary behaviour, western type diet, obesity, diabetes, and hypercholesterolemia. Most of these behavioural risk factors appear to be associated with dementia as well as with risk of cardiovascular diseases (CVDs) and diabetes. This study aims to find out the prevalence of behavioural risk factors and their association with cognitive deficit and dementia. Study design and setting: Cross-sectional survey in a hospital. Subjects and methods: After written informed consent and approval from hospital ethic committee, all subjects (n=2002) above 25 years of age (1016 males and 986 females) were randomly selected and recruited from urban population of Moradabad, North India. Clinical data and risk factors were recorded with the help of case record form and validated questionnaires. Assessment of cognitive decline and dementia was made by a new memory function rating scale and behavioural risk factors by validated questionnaires. The association of behavioral risk factors with dementia was calculated by multivariate logistic regression analysis after adjustment of age and sex, obesity, diabetes and CVDs. Results: Low cognitive activity, low education, sedentary behavior, sleep duration, tobacco intake, alcoholism and western diet, were highly prevalent independent risk factors of dementia. Low education was not associated with risk. Logistic regression analysis revealed that regardless of age and body mass index, sedentary behavior, odds ratio and confidence intervals: (men 0.74 (0.69 - 0.79), women, 0.71 (0.63 - 0.74) and tobacco intake (men 0.88 (0.79 - 0.94), women 0.90 (0.84 - 0.97) and sleep disruption (men 0.80 (0.71 - 0.89), women 0.85 (0.79 - 0.91) were strongly (p<001) and significantly (p<0.001) associated with dementia in both sexes, respectively. Alcoholism (men 0.71 (0.65 - 0.78) was also strongly and significantly (P<001) associated with dementia in men but not in women. Low cognitive activity, (men 0.83 (0.75 - 0.92), (women 0.89 (0.84 - 0.99), and western diet (men 0.88(0.80-0.95), (women 0.89 (0.81 - 0.99) were weakly but significantly (p=0.05) associated with dementia in both sexes. Meditation and prayer was inversely associated with dementia among (men 0.92 (0.85 - 0.99) and (women 0.90 (0.85 - 0.97). Conclusions: It is possible that increased physical activity, no tobacco and alcoholism, optimal sleep, intake of healthy foods, meditation and prayer, high cognitive activity, and good sleep for 6-8 hours, can protect against dementia.
Contingency and Multimodal Communication in the Learning Environment
Authors: McCafferty Steven G , Rosborough Alessandro
Published: March 2023

From a Vygotskian (1997) theoretical perspective, teachers and learners, of necessity, need to listen and respond to one another in a meaningful way, which, significantly, entails some form of role reversal (i.e., student as teacher and teacher as student). van Lier (1996) furthered this approach in relation to second language (L2) classroom environments, emphasizing the need for conversational symmetry between students and teacher so that participation by all includes contributing individual and collective thoughts and experiences in relation to the content of a lesson, or ‘contingent interaction’, which van Lier also based on a similar approach: Instructional Conversation. Furthermore, van Lier linked his perspective to Vygotsky’s (1987) central premise that language (signs) constitutes the primary mediational tool with which we navigate ourselves and the world, which includes not only meaning (znachenie) but sense (smysl), and as applied in the case of the current study to L2 immigrant children growing up in a multilingual society. Moreover, although Vygotsky had recognized the role of proto-gesture (e.g., an infant reaching for an object that is then brought by an adult) as perhaps the earliest form of semiotic mediation, he did not concentrate on nonverbal forms of mediation, nor did van Lier. However, the current research hopes to demonstrate that speech together with nonverbal forms of communication, especially in combination (multimodal ensembles) can constitute an important aspect of creating L2 contingent interaction, and following van Lier, as connected to the Zone of Proximal Development. Additionally, emotional development (Perezhivanie) as tied to contingency and as an aspect of cooperative social relations is given treatment. Data for the study come from a second-grade classroom of L2 learners of English engaged in a read-aloud lesson directed towards L2 language and literacy development.
Masks of Cernunnos
Authors: Savignac Jean-Paul
Published: March 2023

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Revisiting Methodology of Qur’anic Interpretation: A Thematic Contextual Approach to the Qur’an
Authors: Kusroni Kusroni , Zamzami Mukhammad
Published: March 2023

Abstract: This article is aimed to propose a methodological interpretation of the Qur’an with reference to the thematic method. The concept is derived from combining the contextual approach with the thematic method of Qur’anic interpretation. Here, I argue that the contextual approach is relevant to develop the existing thematic tafsir methods that are vastly adopted, mostly among the works of college students in Indonesian Islamic universities. Besides, the approach becomes important in its ability to come up with fresh researches in the tafsir studies, as well as to address challenges and socio-religious problems in contemporary society. Therefore, this article attempts to elaborate one of the contemporary approaches introduced by Abdullah Saeed, which he called the contextual approach. By adopting this approach, thematic tafsir will be more comprehensive, as the object of analysis is not limited to text, of the Qur’anic verses and its commentaries, but also the socio-historical context of the studied verses.
Abstrak: Artikel ini bertujuan untuk menawarkan kajian metodologis dalam diskursus tafsir al-Qur’an, yaitu metode tematik. Tawaran tersebut berasal dari penggabungan pendekatan kontekstual dengan metode tafsir tematik. Di sini, penulis berpendapat bahwa pendekatan kontekstual sangat relevan untuk mengembangkan metode tafsir tematik yang telah ada dan banyak diadopsi dalam karya-karya akademik di perguruan tinggi keislaman Indonesia. Selain itu, pendekatan ini menjadi penting dalam kemampuannya untuk menghasilkan penelitian-penelitian baru dalam studi tafsir, serta untuk menjawab tantangan dan masalah sosial-keagamaan dalam masyarakat kontemporer. Oleh karena itu, artikel ini mencoba mengelaborasi salah satu pendekatan kontemporer yang diperkenalkan oleh Abdullah Saeed, yang disebutnya sebagai pendekatan kontekstual. Dengan mengadopsi pendekatan ini, tafsir tematik akan lebih komprehensif, karena objek analisisnya tidak terbatas pada teks, yaitu ayat-ayat al-Qur’an dan tafsirnya, tetapi juga konteks sosio-historis dari ayat-ayat yang dikaji.
Dialektika Ẓāhir Bāṭin dan Produksi Makna Ishārī dalam Tafsir al-Baḥr al-Madīd
Authors: Isnaini Subi Nur , Adim Fauzan
Published: March 2023

Abstract: This article examines the sufi Qur’anic exegesis of al-Baḥr al-Madīd on how is the dialectic of ẓāhir and bāṭin shaping a new meaning of the Qur’an. By using descriptive analysis, this article argues that Ibn ‘Ajībah is one of the authoritative sufi scholars who tends to interpret the Qur’an with regards to the balanced hermeneutics of the exoteric (ẓāhir) and the esoteric (bāṭin) meanings of it. The existence of the esoteric meaning should not violate the exoteric interpretation. According to Ibn ‘Ajībah, the exoteric meaning becomes the initial basis for the birth of the esoteric interpretation. Related to the symbolic (ishārī) interpretation, it is quite visible when Ibn ‘Ajībah interprets the term al-arḍ in his exegesis. This article finds that there are at least four allegorical meanings with representative of Sufism presented by Ibn ‘Ajībah in terms of al-arḍ, namely: qalb (heart), ashbāḥ (body), nafs (soul), and arḍ al-ḥikmah (wisdom). The four meanings presented are diametrically different from the meaning of arḍ in its linguistic sense which is generally perceived by the most Qur’anic commentators as the ‘earth’ inhabited by humans.
Periwayat Syiah dalam Ṣaḥīḥ al-Bukhārī
Authors: Husein Alwi
Published: March 2023

The article reviews the existance of Shi’ite ḥadīth narrator with various levels, in which their report narrated in Sunni authoritative ḥadīth literature namely Ṣaḥīḥ al-Bukhārī. It attempts to examine the chain of transmission (sanad) in Ṣaḥīḥ al-Bukhārī with various classical and contemporary rijāl al-ḥadīth books, such as Ibn Abī Ḥātim (d. 327), Ibn Ḥibbān (d. 354), Yūsuf al-Mizzī (d. 742), al-Dhahabī (d. 748), Ibn Ḥajar (d. 852), al-Suyūṭī (d. 911), Muḥammad Nāṣir al-Dīn al-Albānī (d. 1420) and Shu’ayb al-Arna’ūṭ (d. 1438), to identify the Shia narrators reported in Ṣaḥīḥ al-Bukhārī. By using historical approach and hadīth narrators (rijāl al-Ḥadīth) analysis, the article finds thirty-two Shia narrators, and twenty-four Rāfiḍah narrators composed in Ṣaḥīḥ al-Bukhārī. That is because in methodological perspective, al-Bukhārī does not put beliefs and theological affiliations of the hadīth narrators as parameters for accepting or rejecting the hadīth.
Ortografi Mushaf Al-Qur'an Nusantara Abad Ke-18 M: Kajian Manuskrip Mushaf al-Qur’an Batokan Kediri
Authors: Zaenatul Hakamah
Published: March 2023

Abstract: This article examines the Qur’anic manuscript found in Batokan, Kediri. The manuscript, which was inherited from Mbah Abdurrahman Batokan, has been perceived by the residents to have a mystical history since its appearance, and to have connection with the charismatic figure of Diponegoro. One of the uniqueness of the manuscripts is that there is no waqf (stop) sign except for the third juz. This article studies the manuscript in two aspects, namely the orthography of the 18th century AD Archipelago manuscripts of the Qur’an; and the distinction of the Batokan Kediri Qur’anic manuscript and its relation to the socio-historical community. This paper concludes that the writing of the 18th century Archipelago manuscripts of the Qur’an, such as the Batokan manuscripts, was a manifestation of the influence of Islamic studies with regards to the struggle for independence and the formation of local culture. Furthermore, the Batokan Mushaf reflects a form of Islamic sacredness which functions as a talisman for the community.
 
Abstrak: Artikel ini mengkaji manuskrip mushaf al-Qur’an yang terletak di Batokan, Kediri. Manuskrip yang merupakan warisan Mbah Abdurrahman Batokan tersebut dianggap memiliki sejarah mistis atas kemunculannya, dan warga meyakini keterkaitan antara mushaf tersebut dengan sosok Pangeran Diponegoro. Keunikan pada manuskrip mushaf tersebut, salah satunya, adalah tidak adanya tanda waqf pada ayat-ayatnya kecuali hanya pada juz ketiga. Artikel ini mengkaji manuskrip tersebut dalam dua aspek, yaitu tentang ortografi mushaf al-Qur’an Nusantara abad ke-18 M; dan tentang distingsi mushaf al-Qur’an Batokan Kediri serta keterkaitannya dengan sosio-historis masyarakat setempat. Tulisan ini menyimpulkan bahwa penulisan mushaf al-Qur’an Nusantara abad ke-18 M, seperti mushaf Batokan, merupakan wujud dari pengaruh kajian keislaman terhadap upaya kemerdekaan dan terbentuknya budaya setempat. Selanjutnya, mushaf Batokan merefleksikan bentuk ekstraksi dari nilai sakralitas keislaman yang difungsikan sebagai “aji-aji” bagi masyarakat untuk dijadikan senjata batin para penduduknya.
Kaidah-kaidah Pemahaman Esoteris Al-Qur'an Abu al-Hasan al-Haralli
Authors: Marsyam Abdul Waris
Published: March 2023

Abstract: This article describes the principles of esoteric understanding of the Qur’an by Abū al-Ḥasan al-Ḥarāllī, a Moroccan sufi and Qur’anic interpreter. Lack of studies have been paid attention to al-Ḥarāllī’s hermeneutical interpretation while he has successfully formulated ten rules on esoteric understanding of the Qur’an. By using descriptive-analytical method, the article argues that al-Ḥarallī’s rules of Qur’anic interpretation is related to the principles in the tafsīr bi al-Ishārah school. Al-Ḥarāllī calls the esoteric interpretation as fahm al-Qur’ān (understanding of the Qur’an) to distinguish it from the exoteric interpretation. Of the ten principles of al-Ḥarāllī’s esoteric understanding, there are three main interrelated principles, namely (1) ma‘rifatullāh (knowing God) through His beautiful Names (asmā’ al-ḥusnā) in the Qur’an, (2) mastering the scope of the Qur’anic text, and (3) self-purification (tazkiyat al-nafs) in order to arrive at the levels of meaning of the Qur’an. 
 
Abstrak: Artikel ini mengkaji tentang kaidah-kaidah pemahaman esoterik al-Qur’an Abū Ḥasan al-Ḥarāllī, seorang sufi dan mufasir al-Qur’an asal Maroko. Tidak cukup banyak kajian akademik yang mengkaji pemahaman al-Qur’an al-Ḥarāllī, padahal dia telah merumuskan sepuluh kaidah tentang pemahaman esoterik atas al-Qur’an. Dengan menggunakan metode deskriptif-analitis, artikel ini berargumen bahwa rumusan kaidah-kaidah tafsir al-Ḥarāllī dikategorikan dalam kaidah-kaidah mazhab tafsīr bi al-Ishārah. Al-Ḥarāllī menyebut tafsir esoterik atas al-Qur’an dengan istilah fahm al-Qur’ān (pemahaman al-Qur’an) untuk membedakannya dengan tafsir eksoterik. Dari kesepuluh kaidah pemahaman esoterik al-Ḥarāllī, terdapat tiga prinsip utama yang saling berkaitan, yaitu (1) Makrifatullah (mengenal Allah) melalui asmā’ al-ḥusnā dalam al-Qur’an; (2) pengetahuan tentang cakupan teks al-Qur’an, dan (3) penyucian diri (tazkiyat al-nafs) untuk mencapai tingkatan-tingkatan makna al-Qur’an.
Argumen Kontra Narasi Terhadap Penolakan Tilawah Langgam Jawa
Authors: M. Yaser Arafat
Published: March 2023

Abstract: The Qur’anic recitation with Javanese style was officially staged at the Istana Negara of the Republic of Indonesia on May 15, 2015 in commemoration of Isra Mi’raj event. Subsequently, various responses emerged from the ulama, both those who supported or rejected TLJ. With critical perspective based on historical anthropology, this article aims to provide counterarguments against four clerics who reject TLJ through their lectures uploaded on YouTube, namely Muhammad Rizieq Shihab (HRS), Buya Yahya (BY), Tengku Zulkarnain (TZ), and Adi Hidayat (AH). This paper argues that the ulama’s rejection of TLJ tends to be based on prejudice, monolithic perspective of Islam, as well as lack of attention to the anthropological aspects of the art of reading the Koran and Javanese-Islamic culture which are actually reflected in TLJ.
 
Abstrak: Tilawah Langgam Jawa (TLJ) pernah ditampilkan secara resmi di Istana Negara RI pada 15 Mei 2015 dalam rangka peringatan Isra Mi’raj. Paska penampilan tersebut, muncul berbagai tanggapan dari para ulama, baik yang mendukung atau menolak TLJ. Dengan menggunakan perspektif kritik berbasis antropologi historis, artikel ini hendak memberi argumen sanggahan terhadap empat ulama penolak TLJ melalui ceramah mereka yang diunggah di YouTube, yaitu Muhammad Rizieq Shihab (HRS), Buya Yahya (BY), Tengku Zulkarnain (TZ), dan Adi Hidayat (AH). Tulisan ini berargumen bahwa penolakan ulama terhadap TLJ cenderung didasari pada prasangka, pandangan Islam yang monolitik dan kurangnya perhatian terhadap aspek antropologi seni baca al-Qur’an dan budaya Jawa-Islam yang sejatinya terefleksikan dalam TLJ.
Prospective analysis of the major risk factors and vascular status in students during the period of education at a medical university
Authors: Evsevyeva M. E. , Eremin M. V. , Sergeeva O. V. , Simhes E. V. , Barabash I. V. , Kudryavtseva V. D. , Kruchkov M. C.
Published: March 2023

Aim. To study the changes of the major risk factors (RFs) and vascular status in students over six years of their education at a medical university.

Material and methods. A total of 667 students aged 17,8±1,2 years were examined in the 1st year and 6th year (162 men, 505 women). Students who entered in the same year were combined into one cohort, while in total 5 cohorts were recruited. The screening examination was carried out as part of the annual intra-university events "Freshman Week", "Graduate Week" by staff of the University Health Center and included the collection of complaints and history, height, body weight, the measurement of peripheral and central blood pressure, as well as the assessment vascular stiffness and metabolic status. Statistical analysis of the material was carried out using SPSS Statistics 23.0.

Results. Analysis of RFs in medical students over 6 years showed a significant increase of the prevalence of hypertension/prehypertension, resting tachycardia, obesity/overweight, malnutrition and physical inactivity. An assessment of cen­tral and peripheral hemodynamics, as well as vascular stiffness of students, revealed an increase in the level of aortic systolic pressure, combined with an increase in peripheral systolic blood pressure and pulse. At the same time, there was no significant increase in some parameters of vascular stiffness, against the background of a 2-fold increase in the prevalence of overweight. Analysis of the metabolic status reveals a significant change in total cholesterol and triglycerides but no alterations in capillary blood glucose.

Conclusion. The data obtained indicate an increase in the prevalence of not only behavioral, but also biological RFs among medical students, as well as the development of preclinical vascular remodeling in them during a six-year education, which can later lead to early cardiovascular diseases. Therefore, widespread screening system of risk factors among students should be developed.
Monocyte response in myocardial infarction in patients with type 2 diabetes
Authors: Kukharchik G. A. , Lebedeva O. K. , Gaykova L. B.
Published: March 2023

Aim. To reveal the features of monocyte response in myocardial infarction (MI) in pa­­tients with type 2 diabetes (T2D).

Material and methods. The study included 121 patients with MI and T2D as follows: 76 — with target glycated hemoglobin (HbA1c), 45 — with elevated HbA1c values. In addition to the standard examination, all patients underwent a blood test for HbA1c on day 1 of MI, while on days 1, 3, 5, and 12±1, monocyte subpopulations were assessed by flow cytometry.

Results. Patients with target HbA1c were older than patients with elevated HbA1c levels. In the group with target HbA1c, the number of CD16(+) monocytes on the 1st day of MI was significantly higher: 61,38 (39,2; 100,08) cells/µl vs 35,7 (28,98; 40,33) cells/µl, p=0,03; on the 3rd day of MI, the number of "intermediate" CD14(+)CD16(+) monocytes was higher: 74,82 (71,78; 83,2) cells/µl vs 25,90 (14,04; 57,12) cells/µl, p=0,03, while the CD16(-) to CD16(+) monocyte ratio on the 3rd day of MI was lower: 8,32 (6 ,87; 10,03) vs 10,81 (8,90; 21,10), p=0,04. At the same time, in the group of patients with target HbA1c values, the level of CD16(+) monocytes on the 3rd day of MI was significantly higher in patients aged <71 years compared with patients ≥71 years: 104,55 (63,64; 149,7) cells/µl vs 55,20 (36,92; 76,59) cells/µl, p=0,03.

Conclusion. In patients with T2D and target HbA1c values, compared with patients with elevated HbA1c, the inflammatory response in MI is associated with higher levels of CD16(+) monocytes on days 1 and 3 of MI, which is more typical for people aged <71 years.
La burbuja de filtros en España. Una comprobación empírica en Facebook e Instagram
Authors: Soria Alonso Sandra , Gil-Torres Alicia
Published: March 2023

A pesar del fenómeno de la sobreinformación, las plataformas tecnológicas han encontrado una nueva forma de acceso a los contenidos para los usuarios mediante la personalización. Esta microsegmentación o microtargeting conlleva una creciente polarización de la política con posturas ideológicas enfrentadas entre sí creando cámaras de resonancia cada vez más difíciles de desarticular. Con esta investigación se pretende exponer la teoría de la "burbuja de filtros", enunciada por Eli Pariser (2017), en el contexto español en Facebook e Instagram, siendo esta última red apenas investigada en relación con esta temática. Mediante la creación de tres cuentas ficticias de tendencia de derechas, izquierdas y neutra en ambas plataformas, y en un plazo de 6 semanas, se pretendió alcanzar tres objetivos: (1) determinar el número de días que son necesarios en cada cuenta para que actúen los algoritmos y se perciban en primer lugar los contenidos afines y así descubrir qué predisposiciones actúan antes; (2) observar si la burbuja de filtros conduce a una cámara de resonancia que potencie la polarización política y la exaltación de los extremos en esas redes sociales; y (3) definir la temática de las noticias que más se repite en las diferentes cuentas de las dos plataformas sociales y qué medios son los emisores. Los resultados y conclusiones apuntaron que tanto Facebook como Instagram cuentan con algoritmos que personalizan las interacciones en un corto periodo de tiempo, lo que aviva la polarización y la crispación en el debate político con medios recurrentes para potenciarlo.
La inclusión digital en el ecosistema de TikTok: análisis del hashtag #Cosas que me dicen
Authors: Micaletto-Belda Juan Pablo , Martín-Ramallal Pablo
Published: March 2023

El confinamiento provocado por el Covid-19 ha acelerado la expansión de redes sociales como TikTok (Tamara, 2020), que está experimentado un profundo crecimiento entre los usuarios más jóvenes. Los centennials de esta red se centran principalmente en la producción y difusión de tutoriales, videoselfies, coreografías o vídeos en tono humorísticos diseñados para entretener a sus seguidores (Suárez-Álvarez y García-Jiménez, 2021). Sin embargo, la plataforma también puede ser empleada para dar voz a las minorías, denunciar situaciones de desigualdad o reivindicar los derechos de determinados colectivos (Sánchez-Castillo y Mercado-Sáez, 2021). Con este propósito, la red puso en marcha el hashtag #Cosas que me dicen; una iniciativa inclusiva para fomentar la lucha contra la desigualdad y la discriminación que sufren las personas. Este hashtag invita a los ciudadanos a denunciar la exclusión que han sufrido en determinados momentos de sus vidas. El objetivo del estudio es identificar las temáticas abordadas entre las publicaciones y conocer las valoraciones emitidas por un grupo de expertos sobre estas. La metodología se compone de dos técnicas cualitativas diferentes: el análisis de contenido y un focus group. Se preparó una ficha de análisis de contenido y un cuestionario semiestructurado, ambos de elaboración propia. Tras analizar un total de 200 vídeos y conocer las percepciones de tres doctores en comunicación y tres doctores en educación, se observa que los prosumidores de esta red han denunciado situaciones de rechazo originadas por el lugar de nacimiento, el género, el aspecto físico, la orientación sexual, la profesión, la composición de sus familias, las creencias o las aficiones. A modo de conclusión, la diversidad de temas tratados muestra que TikTok representa un escaparate idóneo para luchar contra las desigualdades, pero es necesario desarrollar otras acciones complementarias, en el ámbito comunicativo y educacional, que permitan generar un cambio positivo perdurable en el tiempo.
Heterotopías sexuales, una localización epistemológica
Authors: Galván Francisco Hernández
Published: March 2023

Resumen El presente ensayo analiza el concepto de «heterotopía» propuesto por Michel Foucault como una localización epistemológica a propósito de las imbricaciones existentes entre las dimensiones espaciales y sexuales. Así, el objetivo de este ensayo es trazar una asociación entre la vida urbana y aquellas libertades singulares que se pretender obtener en el imaginario de una ciudad. Para tales cometidos el texto reúne una serie de entrevistas etnográficas que engloban, por un lado, la caracterización de un desplazamiento localizado por varones homosexuales y, por el otro, un recurso epistemológico para pensar dichos movimientos espaciales.
Common mental disorder and related factors to the work of physiotherapists in the COVID-19 pandemic
Authors: Monteiro Gabriel Araújo de Souza , Santos Washington José dos , Ceballos Albanita Gomes da Costa de , Barbosa Juliana Fernandes de Souza , Fittipaldi Etiene Oliveira da Silva
Published: March 2023

Abstract Introduction The physiotherapists were one of the health professional categories on the Coronavirus (COVID-19) pandemic front line, however little is known how the pandemic has affected the mental health of these professionals. Objective To analyze the relation-ship between the presence of common mental disorder (CMD) and elements related to the work of physiotherapists who have been assisting patients with COVID-19. Methods: This is a cross-sectional survey study composed by physiotherapists from four states of Brazil: Alagoas, Paraíba, Pernambuco and Rio Grande do Norte. Working conditions evaluated were type of contract, weekly worked hours, time working, job satisfaction, and psychosocial aspects related to work. The CMD assessment was performed using the Self-Reporting Questionnaire-20 (SRQ-20). Results A total of 288 physiotherapists answered the electronic form, out of which 76.2% had CMD. Fear of reinfection (OR 2.75, 95%CI: 1.35-5.63) and previous infection by COVID-19 (OR: 2.03, 95%CI: 1.09-3.78) were factors related to a higher chance of risk of CMD. However, those who reported being satisfied with the work (OR: 0.28, 95%CI 0.11-0.72) and being more than 30 years old (OR: 0.46, 95%CI 0.24-0.88) had a lower chance of CMD risk. Conclusion Physiotherapists showed a higher prevalence of CMD. Fear of reinfection and previous infection by COVID-19 were risk factors to CMD, while satisfaction with the work and being more than 30 years old were protective factors to CMD.
Proposta de ferramenta para diagnóstico do grau de inovação percebido em empresas do ambiente construído
Authors: Timm Janaine Fernanda Gaelzer , Casarin Roberta Picanço , Silva Deividi Maurente Gomes da , Bellaver Gustavo Bridi , Pagnussat Daniel Tregnago , Viana Daniela Dietz
Published: March 2023

Resumo Anecessidade de inovar está diretamente relacionada ao crescimento econômico e à competitividade. Algumas barreiras são observadas no processo de implantação da inovação na construção civil, a exemplo da falta de entendimento dos benefícios da inovação no setor. Diante da importância dos agentes envolvidos na construção como facilitadores do processo de inovação, é necessário identificar suas percepções acerca do tema. No presente estudo é proposta uma ferramenta que objetiva captar a percepção da inovação pelos agentes internos da construção civil e que permite a comunicação do diagnóstico da inovação em uma empresa. A ferramenta desenvolvida está dividida em três etapas: (i) desenvolvimento da estrutura através da revisão teórica; (ii) aplicações em estudo de caso e no meio acadêmico, gerando ajustes ao questionário e ao infográfico; e (iii) desenvolvimento da versão final da ferramenta e de sugestões de ações por cada categoria). A proposta da ferramenta mostrou-se eficiente para o diagnóstico acerca da percepção dos agentes da inovação, além de trazer resultados práticos no embasamento para tomada de decisão nas empresas.
Estudo das propriedades reológicas e microestruturais de ligante geopolimérico à base de cinza volante
Authors: Araújo Lucas Benício Rodrigues , Bezerra Ana Karoliny Lemos , Silva Leonária Araújo , Chaves Andressa Cristina Borges , Costa Heloina Nogueira da , Babadopulos Lucas Feitosa de Albuquerque Lima
Published: March 2023

Resumo Os geopolímeros figuram como uma alternativa potencial aos ligantes de cimento Portland em algumas aplicações. Contudo, existem muitas lacunas de pesquisa a serem preenchidas dentro dessa temática. Assim, este estudo teve como objetivo investigar as propriedades reológicas e mecânicas de pastas geopoliméricas à base de cinza volante Classe F ativadas por uma solução de NaOH e Na2SiO3, com relações ativador/precursor de 0,5, 0,6 e 0,7, em massa. Além disso, foram realizadas análises microestruturais e químicas. As propriedades reológicas foram determinadas a partir de ensaios de fluxo com taxas de cisalhamento variando de 0 s-1 a 100 s-1 a 25 ºC. A análise mecânica foi realizada a partir de ensaios de resistência à compressão simples nas pastas endurecidas. Os resultados de resistência à compressão simples indicaram melhores valores para menores relações de ativador/precursor. Nos ensaios de fluxo, o material comportou-se como um fluido pseudoplástico e, com o aumento da relação ativador/precursor, houve redução dos valores de viscosidade aparente. Assim, avaliando-se os resultados mecânicos e reológicos, percebeu-se que a pasta que apresentou melhores propriedades foi a de relação ativador/precursor 0,6.