bluuebunny/crossref_metadata_2025 huggingface dataset:
Factors influencing the outcomes of minimally invasive total hip arthroplasty: a systematic review
Authors: Migliorini Filippo , Pintore Andrea , Eschweiler Joerg , Oliva Francesco , Hildebrand Frank , Maffulli Nicola
Published: May 2022

Introduction

The present systematic review investigated possible factors which may influence the surgical outcome of minimally invasive surgery for total hip arthroplasty (MIS THA).

Methods

In January 2022, the Embase, Google Scholar, PubMed, and Scopus databases were accessed. All the clinical trials investigating the clinical outcome of MIS THA were considered.

Results

Data from 9486 procedures were collected. Older age was moderately associated with greater Visual Analogue Scale (VAS) (P = 0.02) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) (P = 0.009) at last follow-up, and shorter surgical duration (P = 0.01). Greater body mass index (BMI) at baseline was moderately associated with greater cup anteversion (P = 0.0009), Oxford Hip Score (OHS) at last follow-up (P = 0.04), longer surgical duration (P = 0.04), increased leg length discrepancy (P = 0.02), and greater rate of infection (P = 0.04). Greater VAS at baseline was weakly associated with greater VAS at last follow-up (P < 0.0001), total estimated blood lost (P = 0.01), and lower value of Harris Hip Score (HHS) (P = 0.0005). Greater OHS at baseline was associated with greater post-operative VAS (P = 0.01). Greater WOMAC at baseline was associated with lower cup anteversion (P = 0.009) and greater VAS (P = 0.02). Greater HHS at baseline was associated with shorter hospitalisation (P = 0.001).

Conclusion

Older age and greater BMI may represent negative prognostic factors for MIS THA. The clinical outcome is strongly influenced by the preoperative status of patients.
Ketogenic diet ameliorates inflammation by inhibiting the NLRP3 inflammasome in osteoarthritis
Authors: Kong Ganggang , Wang Jinyang , Li Rong , Huang Zhiping , Wang Le
Published: May 2022

Background

The nucleotide-binding domain, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) inflammasome has been reported to be involved in the pathological process of osteoarthritis (OA) inflammation. Here, we investigated the ketogenic diet (KD), which has been previously demonstrated to inhibit NLRP3 inflammasome activation, to elucidate its protective mechanism against OA in rats.

Methods

Anterior cruciate ligament transaction (ACLT) together with partial medial meniscectomy was used to create a rat knee joint OA model. After treatment with KD or standard diet (SD) for 8 weeks, the knee specimens were obtained for testing.

Results

The KD significantly increased the content of β-hydroxybutyrate (βOHB) in rats. Compared to the SD group, the KD significantly reduced the damage caused by OA in the articular cartilage and subchondral bone. The NLRP3 inflammasome and inflammatory cytokines interleukin-1 β (IL-1β) and IL-18 were significantly increased in the SD group compared with the sham group, while their expression was significantly decreased in rats treated with the KD. In addition, MMP13 was significantly decreased in the KD group compared to that in the SD group, while COL2 was significantly increased.

Conclusions

KD can protect the articular cartilage and subchondral bone in a rat OA model by inhibiting NLRP3 inflammasome activation and reducing the OA inflammatory response.
The role of biomarkers in personalized immunotherapy
Authors: Sankar Kamya , Ye Jing Christine , Li Zihai , Zheng Lei , Song Wenru , Hu-Lieskovan Siwen
Published: May 2022

Background

Immune checkpoint inhibitors have revolutionized cancer therapeutic paradigm and substantially improved the survival of patients with advanced malignancies. However, a significant limitation is the wide variability in clinical response.

Main text

Several biomarkers have been evaluated in prior and ongoing clinical trials to investigate their prognostic and predictive role of patient response, nonetheless, most have not been comprehensively incorporated into clinical practice. We reviewed published data regarding biomarkers that have been approved by the United States Food and Drug Administration as well as experimental tissue and peripheral blood biomarkers currently under investigation. We further discuss the role of current biomarkers to predict response and response to immune checkpoint inhibitors and the promise of combination biomarker strategies. Finally, we discuss ideal biomarker characteristics, and novel platforms for clinical trial design including enrichment and stratification strategies, all of which are exciting and dynamic to advance the field of precision immuno-oncology.

Conclusion

Incorporation and standardization of strategies to guide selection of combination biomarker approaches will facilitate expansion of the clinical benefit of immune checkpoint inhibitor therapy to appropriate subsets of cancer patients.
Impact of crustal deformation detection by the DSI (difference of split-band interferograms) method with PALSAR-2 data: a case study on the 2016 Kumamoto Earthquake
Authors: Ozawa Taku , Himematsu Yuji
Published: May 2022

Interferometric synthetic aperture radar (InSAR) is a useful tool for detecting surface deformations at high spatial resolutions. When InSAR is applied to large surface deformations, clear fringes with complicated phase gaps often appear in the interferograms. Although the surface deformations in such areas provide valuable data for earthquake research and disaster investigation, it is difficult to convert the complicated interferometric phase to surface deformation information because of the difficulties associated with phase unwrapping. To resolve these difficulties, we created multiple SAR pairs with different frequencies using a bandpass filter and calculated the difference between the interferograms generated from these SAR pairs (referred to as the DSI analysis in this study). Generally, the obtained difference corresponds to SAR observations using long-wavelength radar. Therefore, phase wrap is less likely to occur, simplifying phase unwrapping. We applied the DSI analysis to PALSAR-2 data pairs for the 2016 Kumamoto Earthquake and successfully identified large crustal deformations with complicated phase gaps in the vicinity of the surface ruptures. Comparing these results with the crustal deformations observed with global navigation satellite system measurements, the root-mean-squares of the differences were found to be approximately 4 cm. Although this accuracy was lower than that of conventional InSAR, it was nearly equivalent to that of offset-tracking analysis. It should be noted that the spatial resolution of the DSI analysis was significantly improved compared to that of offset-tracking analysis. A disadvantage of this method is that its detection accuracy is significantly degraded in zones with low coherence owing to noise amplification. The standard deviation of the noise component was approximately 2 cm for pixels with coherence > 0.7. However, for pixels with a coherence < 0.2, the standard deviation was > 10 cm, and the noise component occasionally exceeded 1 m. Despite its disadvantages, this method is effective for detecting large crustal deformations with high spatial resolution in areas where conventional InSAR processing is inappropriate.

Graphical Abstract
Bound state solutions and thermodynamic properties of modified exponential screened plus Yukawa potential
Authors: Antia Akaninyene D. , Okon Ituen B. , Isonguyo Cecilia N. , Akankpo Akaninyene O. , Eyo Nsemeke E.
Published: May 2022

In this research paper, the approximate bound state solutions and thermodynamic properties of Schrӧdinger equation with modified exponential screened plus Yukawa potential (MESPYP) were obtained with the help Greene–Aldrich approximation to evaluate the centrifugal term. The Nikiforov–Uvarov (NU) method was used to obtain the analytical solutions. The numerical bound state solutions of five selected diatomic molecules, namely mercury hydride (HgH), zinc hydride (ZnH), cadmium hydride (CdH), hydrogen bromide (HBr) and hydrogen fluoride (HF) molecules were also obtained. We obtained the energy eigenvalues for these molecules using the resulting energy eigenequation and total unnormalized wave function expressed in terms of associated Jacobi polynomial. The resulting energy eigenequation was presented in a closed form and applied to study partition function (Z) and other thermodynamic properties of the system such as vibrational mean energy (U), vibrational specific heat capacity (C), vibrational entropy (S) and vibrational free energy (F). The numerical bound state solutions were obtained from the resulting energy eigenequation for some orbital angular quantum number. The results obtained from the thermodynamic properties are in excellent agreement with the existing literature. All numerical computations were carried out using spectroscopic constants of the selected diatomic molecules with the help of MATLAB 10.0 version. The numerical bound state solutions obtained increases with an increase in quantum state.
Prevalence and outcome of sepsis in respiratory intensive care unit
Authors: Madkour Ashraf M. , ELMaraghy Ashraf A. , Elsayed Mona M.
Published: May 2022

Background

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to an infection.

Objective

To assess the prevalence and outcome of sepsis in RICU

Patients and methods

The study was conducted upon 403 patients admitted at RICU of the Abbassia Chest Hospital, Cairo, Egypt; 100 of them had sepsis either on admission or acquired in the RICU during the period from May 2019 to November 2019. Severity of illness was assessed by Acute Physiology and Chronic Health Evaluation II (APACHE II score), which was recorded within 24 h from patient admission. Quick sepsis-related organ failure assessment (qSOFA) score was recorded in emergency room, and sepsis-related organ failure assessment (SOFA) score was recorded on ICU admission and on the 3rd and 7th day of ICU stay. Type of infection (community or hospital acquired), infection site, and pathogenic organisms, all were recorded. Assessment was done also regarding mechanical ventilation, length of RICU stay, the presence of comorbidities, survived patients, and dead ones, as regards causes of death and risk factors.

Results

The study included 100 cases with sepsis out of 403 admitted cases in the same duration with frequency 24%. Among sepsis patients, 72% were males and 28%were females, with mean age 51.62 ± 18.62 years. The main diagnosis was pneumonia (62%), and the main comorbidity was diabetes mellitus (23%). There was significant increase in age among non-survivors when compared with survivors. There was significant increase in number of mechanically ventilated patients and a highly significant incidence of complications and need for vasoactive drugs among non-survivors when compared with survivors. There was a highly significant higher APACHE II score on the 1st day of admission among non-survivor patients. The SOFA score was significantly higher on the 1st day of admission and significantly higher on the 3rd and 7th day of admission among non-survivor patients when compared to survived patients.

Conclusion

The current study showed that sepsis affects nearly one quarter of cases admitted at RICU, and it is usually associated with higher mortality rate in those patients.

Trial registration

ClinicalTrials.gov NCT05240157. Registered February 15, 2022. Retrospectively registered.
Nationwide Industry-Led Community Exercise Program for Men With Locally Advanced, Relapsed, or Metastatic Prostate Cancer on Androgen-Deprivation Therapy
Authors: Schumacher Oliver , Galvão Daniel A. , Taaffe Dennis R. , Spry Nigel , Hayne Dickon , Tang Colin , Chee Raphael , Newton Robert U.
Published: May 2022

PURPOSE:

Androgen-deprivation therapy in patients with prostate cancer (PCa) is associated with considerable side effects and secondary comorbidities such as overweight/obesity and cardiovascular disease. The aim of this study was to investigate the effectiveness of an industry-led, treatment-integrated, community-based exercise program on outcomes of body weight, cardiovascular health, and physical function.

PATIENTS AND METHODS:

PCa patients with locally advanced, relapsed, or metastatic disease receiving leuprorelin acetate were enrolled across multiple sites in Australia and assigned supervised group exercise undertaken weekly or biweekly (ie, 16 exercise sessions in total) for 10-18 weeks, consisting of aerobic and resistance training performed at moderate-to-vigorous intensity.

RESULTS:

Between 2014 and 2020, 760 participants completed the baseline and follow-up assessment. Participants were age 48-94 years, and most were either overweight (42.1%) or obese (38.1%). Program compliance was high, with 90% of participants completing all 16 exercise sessions. There was a small but significant reduction in waist circumference (–0.9 cm; 95% CI [–1.2 to –0.5]; P < .001) and no change in weight or body mass index. Systolic (–3.7 mmHg; 95% CI [–4.8 to –2.6]; P < .001) and diastolic (–1.7 mmHg; 95% CI [–2.3 to –1.0]; P < .001) blood pressure were significantly lower after the program. Furthermore, significant improvements were seen in cardiorespiratory fitness and muscle strength ( P < .001). For most of the investigated outcomes, participants with poorer initial measures had the greatest benefit from participating in the program.

CONCLUSION:

The community exercise program was feasible and effective in preventing weight gain, reducing blood pressure, and improving physical function in patients with PCa on androgen-deprivation therapy.
The Road Not Taken: Pearl McGill and the Promise of Inclusive Unionism, 1894–1914
Authors: Weaver Janet K.
Published: May 2022

Pearl McGill's path from an officer in a union affiliated with the American Federation of Labor (AFL) to an organizer for the Industrial Workers of the World (IWW) offers an alternative lens through which to view industrial unionism at the critical juncture of the legendary “Bread and Roses” strike in Lawrence, Massachusetts. Her role in the strikes of button workers in Iowa and textile workers in New England between 1911 and 1913 shines a light on the ways in which grassroots activists invested hope that AFL “federal labor unions” (local unions directly affiliated with the national AFL) might serve as a vehicle for their inclusive union aspirations. Her contribution enhances our understanding of the strategies of the Women's Trade Union League (WTUL) and the contested terrain of ethnicity and gender on which its leaders sought to organize women factory workers, constrained as they were by their loyalty to the AFL.
Dual regulation of the actin cytoskeleton by CARMIL-GAP
Authors: Jung Goeh , Pan Miao , Alexander Christopher J. , Jin Tian , Hammer John A.
Published: May 2022

Capping protein Arp2/3 myosin I linker (CARMIL) proteins are multi-domain scaffold proteins that regulate actin dynamics by regulating the activity of capping protein (CP). Here, we characterize CARMIL-GAP (GAP for GTPase-activating protein), a Dictyostelium CARMIL isoform that contains a ∼130 residue insert that, by homology, confers GTPase-activating properties for Rho-related GTPases. Consistent with this idea, this GAP domain binds Dictyostelium Rac1a and accelerates its rate of GTP hydrolysis. CARMIL-GAP concentrates with F-actin in phagocytic cups and at the leading edge of chemotaxing cells, and CARMIL-GAP-null cells exhibit pronounced defects in phagocytosis and chemotactic streaming. Importantly, these defects are fully rescued by expressing GFP-tagged CARMIL-GAP in CARMIL-GAP-null cells. Finally, rescue with versions of CARMIL-GAP that lack either GAP activity or the ability to regulate CP show that, although both activities contribute significantly to CARMIL-GAP function, the GAP activity plays the bigger role. Together, our results add to the growing evidence that CARMIL proteins influence actin dynamics by regulating signaling molecules as well as CP, and that the continuous cycling of the nucleotide state of Rho GTPases is often required to drive Rho-dependent biological processes.
DYRK2 maintains genome stability via neddylation of cullins in response to DNA damage
Authors: Kawamura Akira , Yoshida Saishu , Aoki Katsuhiko , Shimoyama Yuya , Yamada Kohji , Yoshida Kiyotsugu
Published: May 2022

Neural precursor cell-expressed developmentally down-regulated 8 (NEDD8), an ubiquitin-like protein, is an essential regulator of the DNA damage response. Numerous studies have shown that neddylation (conjugation of NEDD8 to target proteins) dysfunction causes several human diseases, such as cancer. Hence clarifying the regulatory mechanism of neddylation could provide insight into the mechanism of genome stability underlying the DNA damage response (DDR) and carcinogenesis. Here, we demonstrate that dual-specificity tyrosine-regulated kinase 2 (DYRK2) is a novel regulator of neddylation and maintains genome stability. Deletion of DYRK2 leads to persistent DNA double-strand breaks (DSBs) and subsequent genome instability. Mechanistically, DYRK2 promotes neddylation through forming a complex with NAE1, which is a component of NEDD8-activating enzyme E1, and maintaining its protein level by suppressing polyubiquitylation. The present study is the first to demonstrate that DYRK2 controls neddylation and is necessary for maintaining genome stability.

This article has an associated First Person interview with the first author of the paper.
Puncture performance tests reveal distinct feeding modes in pinniped teeth
Authors: Peredo Carlos Mauricio , Ingle Danielle N. , Marshall Christopher D.
Published: May 2022

Marine mammals have undergone a dramatic series of morphological transformations throughout their evolutionary history that facilitated their ecological transition to life in the water. Pinnipeds are a diverse clade of marine mammals that evolved from terrestrial carnivorans in the Oligocene (∼27 million years ago). However, pinnipeds have secondarily lost the dental innovations emblematic of mammalian and carnivoran feeding, such as a talonid basin or shearing carnassials. Modern pinnipeds do not masticate their prey, but can reduce prey size through chopping behavior. Typically, small prey are swallowed whole. Nevertheless, pinnipeds display a wide breadth of morphology of the post-canine teeth. We investigated the relationship between dental morphology and pinniped feeding by measuring the puncture performance of the cheek-teeth of seven extant pinniped genera. Puncture performance was measured as the maximum force and the maximum energy required to puncture a standardized prey item (Loligo sp.). We report significant differences in the puncture performance values across the seven genera, and identify three distinct categories based on cheek-teeth morphology and puncture performance: effective, ineffective and moderate puncturers. In addition, we measured the overall complexity of the tooth row using two different metrics, orientation patch count rotated (OPCR) and relief index (RFI). Neither metric of complexity predicted puncture performance. Finally, we discuss these results in the broader context of known pinniped feeding strategies and lay the groundwork for subsequent efforts to explore the ecological variation of specific dental morphologies.
DEVELOPMENT AND RESEARCH OF BIOMETRIC METHODS AND MEANS OF INFORMATION PROTECTION
Authors: Kurmashev Olzhas
Published: May 2022

The article reveals the importance of biometrics, its types and meth-ods as a means of protecting information data. The article discusses the development of a facial shape recognition method for displaying in a web resource, the capabilities of identification phases (authorization, authentication) have been reviewed.
Ciclo de mejora docente en Patrimonio Urbano y Planeamiento. Contaminación visual y perceptiva en el entorno de protección de los Bienes de Interés Cultural
Authors: Ostos Prieto Francisco Javier
Published: May 2022

Inserto en el Programa de Formación e Innovación Docente del Profesorado de la Universidad de Sevilla se ha realizado un Ciclo de Mejora e innovación Docente en la asignatura del Grado de Fundamentos en Arquitectura titulada Patrimonio Urbano y Planeamiento. Dentro de la asignatura se ha elegido la contaminación visual y perceptiva en el patrimonio como escenario para realizar el CIMA. El objetivo es mejorar la experiencia docente desde la perspectiva del profesor y el estudiante y reflejar la experiencia realizada en la asignatura a través de cambios en el modelo metodológico, elaboración de un mapa de contenidos y la consecución de tareas y actividades en el aula.
Los estereotipos de género en las producciones audiovisuales: diseño y validación de la tabla de análisis EG_5x4
Authors: Saneleuterio-Temporal Elia
Published: May 2022

Los productos culturales de la educación no formal, y en concreto los difundidos por televisión y plataformas streaming, incluidas no ficción y animación infantil, proponen entre sus figuraciones personajes estereotipados en su construcción de género. Según investigaciones previas, identificarlos y combatirlos favorece la erradicación de ideas sexistas relacionadas con violencias machistas. Por ello, el objetivo que se planteó fue diseñar y validar una tabla de análisis de estereotipos sexuales presentes en cualquier producto audiovisual. El proceso siguió un protocolo de 3 fases (Garrido et al., 2015): 1) Se revisó la literatura publicada, se extrajeron rasgos relacionados con estereotipos de género, se completó la redacción de los ítems y se redistribuyeron, en parejas, en 5 categorías: corporal, actitudinal, social, afectivo-sexual, audiovisual. 2) El borrador fue sometido a un proceso de validación experta por 27 juezas y 8 jueces, cuyas aportaciones cuantitativas determinaron un índice de validez de constructo de .71. 3) Con sus sugerencias cualitativas se ajustaron contenido y claridad. El resultado es el diseño de la tabla EG_5x4 para el análisis de estereotipos de género en películas, series u otros productos audiovisuales, que se presenta, se discute y se compara con otras existentes, para su utilización en ulteriores investigaciones. PALABRAS CLAVES · KEYWORDS Materiales Audiovisuales; Coeducación; Estereotipos de Género; Instrumentos de Medición; Educación No Formal Audio-visual Materials; Coeducation; Gender Stereotypes; Measuring Instruments; Nonformal Education
Por una Educación Maker Inclusiva. Revisión de la literatura (2016-2021).
Authors: Gutiérrez-Esteban Prudencia , Jaramillo-Sánchez Gema
Published: May 2022

El movimiento maker ha causado gran interés en el ámbito educativo, dando lugar a la educación maker. Se realiza una revisión de la literatura con el objetivo de realizar un estudio sobre cómo la educación maker contribuye a la inclusión social y educativa de los colectivos más vulnerables y concretamente, las personas con discapacidad. Para ello, se realizó una búsqueda en diversas bases de datos atendiendo a la combinación de varios descriptores y filtros de búsqueda. Finalmente, tras ser sometidos a un cribado y tomando en consideración los criterios de inclusión y exclusión establecidos, se evalúan un total de 11 artículos. Los resultados muestran que la educación maker tiene lugar principalmente, en el ámbito no formal, llevando a la práctica actividades enriquecedoras, mediante el uso de recursos y espacios maker. Igualmente, los hallazgos apuntan a que el movimiento maker con una finalidad educativa, facilita el desarrollo de capacidades en estas personas, así como la mejora de la autoestima y la autopercepción de sí mismas. Además, la formación especializada en educación maker de las y los responsables de ponerlas en práctica, facilita la inclusión de estos colectivos, ofreciéndoles grandes beneficios tanto académicos como sociales.
Las tecnologías como elemento mediador de procesos de autoinclusión digital de mujeres rurales
Authors: Sierra Daza María Caridad , Fernández Sánchez María Rosa
Published: May 2022

El presente artículo recoge una investigación sobre el proceso de autoinclusión digital de mujeres de zonas rurales extremeñas. El objetivo central es identificar los facilitadores de inclusión de las mujeres rurales en las tecnologías digitales, abordando la autodefinición sobre el nivel de autonomía en el manejo de estos medios, y la existencia de diferencias en la percepción sobre estos facilitadores en función de la edad. Para ello, se parte de un enfoque cuantitativo y una metodología descriptiva, mediante la aplicación del Cuestionario SIRWOP a una muestra aleatoria de 400 mujeres (entre 15 y 75 años) de entornos rurales situados en la provincia de Cáceres. Los resultados obtenidos, revelan diferentes niveles de autonomía, donde las mujeres jóvenes con más estudios e ingresos presentan un mejor desempeño tecnológico. También, se observan diferencias en la valoración de los posibilitadores para el uso de las tecnologías, así las mujeres jóvenes cuentan con un mayor apoyo del entorno. En general, existe una percepción positiva sobre los aspectos facilitadores de inclusión digital, destacando el apoyo de familiares, y un mejor acceso a las tecnologías. Para concluir, se ofrecen orientaciones dirigidas a la promoción de medidas enfocadas al desarrollo de habilidades digitales avanzadas y usos rutinarios.
Evaluar el uso de las redes sociales de lectura en la educación literaria en contextos formales e informales. Diseño y validación de la herramienta RESOLEC
Authors: Hernández Heras Lucía , Muela Bermejo Diana , Tabernero Sala Rosa
Published: May 2022

Con la aparición de las redes sociales de lectura, los usuarios pueden interactuar entre iguales en torno a una misma afinidad, convirtiendo la lección en una práctica dominada por la cultura participativa. Ante la atención que están recibiendo estas plataformas, se ha diseñado y validado la herramienta RESOLEC, con la que se pretende ofrecer a los docentes de Secundaria y Bachillerato un instrumento validado que les permita evaluar la capacidad de estas redes para fomentar el aprendizaje informal y la educación literaria. Para crear la batería de indicadores, nos fundamentamos en la Teoría de la Actividad y en el paradigma de la educación literaria. Para validarla, emprendimos una prueba de jueces expertos y una prueba piloto con una muestra aleatoria de 10 redes sociales. Tras la aplicación de las pruebas y estadísticos correspondientes, se reformularon 10 indicadores y se suprimieron 2 y todas las dimensiones se se consideraron idóneas. 52 ítems, agrupados en dos escalas de 3 y 4 dimensiones respectivamente, integran el instrumento definitivo.
PENDAMPINGAN MANAJEMEN USAHA PRODUKSI MODIFIED CASSAVA FLOUR (MOCAF) BAGI KWT NGUDI SARI, DESA KEMIRI, KECAMATAN TANJUNGSARI, GUNUNG KIDUL
Authors: Astuti Fatma Hermining , Jatiningrum Wandhansari Sekar
Published: May 2022

KWT Ngudi Sari is one of the farmer groups in Kemiri Village, Gunung Kidul which is actively produce various processed cassava products, such as mocaf flour. The abundant yield of cassava in Kemiri Village and the advantages of mocaf flour, which is good for health become the opportunity for KWT Ngudi Sari to develop their business. However, KWT Ngudi Sari faced several obstacles in their business management that were carried out, such as the lack of detailed calculations for selling prices, unclear division of labor within the organization, SOPs had not been written with good standard flow, and the labels of mocaf flour packaging does not meet the standards. For this reason, a series of community service activity programs in the form of counseling and assistance for KWT Ngudi Sari were designed, specifically to develop mocaf flour processed businesses. These activities include counseling and mentoring related to organizational design, determining the cost of production, selling prices, and BEP, counseling and preparation of informative SOPs, as well as counseling and assistance in making good and standard packaging labels.
PEMBERDAYAAN BANK SAMPAH BERBASIS SISTEM INFORMASI ONLINE (SiOn)
Authors: Nurjanah Adhianty , Sakir Sakir
Published: May 2022

The lack of public awareness and knowledge of the importance of managing household waste independently through a waste bank; The unavailability of an online information system that functions as communication, information and education related to the management of waste banks; Do not have promotional media for krajinan products originating from household waste; The lack of support from the village government in managing waste independently through this waste bank is a problem that occurs in garbage banks located in RW 17 Kradenan, Banyuraden Village, Gamping District, Sleman Regency, DIY. Based on these problems, this community service aims to empower the Kradenan Berseri waste bank through an online-based information system (SIOn). The use of online-based information systems (SIOn) will have an impact, waste banks are able to adapt quickly to stakeholder needs. In addition, this online-based information system (SIOn) can be used as a media for promotion and education as well as literacy related to the importance of managing household waste through waste banks to the public.
PEMBERDAYAAN MASYARAKAT DESA BANJAROYO, KALIBAWANG, KULON PROGO DALAM BIDANG KESEHATAN
Authors: Rustiawan Asep , Ruminda Afdilla Puja , Adriansyah Bobby , Prasetya Virdinan Dharma
Published: May 2022

The community of Banjaroyo, Kalibawang - Kulon Progo Yogyakarta has poor clean and healthy lifestyle habits (CHLH) which still do not like washing hands with soap and unhealthy snacks. Besides that, knowledge of dengue disease is also still low with the condition of dengue endemic areas. The 71st period of the UAD Community Service Program conducted from 23 January to 20 February 2019 was intended to empower the community through the dissemination of CHLH and DHF. The method used consisted of lectures, demonstrations and special practices for Hand Washing with Soap, while for Snacks and DHF the lecture method was used. The impact of these program are the increased knowledge and skills of the community in the field of CHLH, especially how to wash hands properly using soap, choose healthy snacks and efforts to prevent dengue disease.
UPAYA PEMBERDAYAAN MASYARAKAT BIDANG KESEHATAN MENUJU DESA SIAGA OLEH KKN UAD DI WATU GAJAH DAN MERTELU, GENDANGSARI, GUNUNG KIDUL
Authors: Pramudyani Avanti Vera Risti , Setiawan Arif , Fajariyansyah Arif , Aji Galih Lastiko
Published: May 2022

Pemberdayaan masyarakat bidang kesehatan adalah isu yang dicanangkan oleh pemerintah Indonesia sejak tahun 2006. Tujuan dari kebijakan tersebut adalah memberdayakan masyarakat dalam mengidentifikasi dan memecahkan masalah kesehatan pada level komunitas terkecil yaitu desa. Bentuk implementasi program berupa membangun Desa Siaga dengan kemampuan mengidentifikasi dan memecahkan masalah kesehatan yang dilakukan oleh anggota masyarakat, institusi masyarakat, kepemimpinan masyarakat, dan tersedia akses informasi kesehatan. Tujuan akhir dari program ini adalah meningkatkan Indeks Pembangunan Masyarakat (IPM). Desa Watu Gajah dan Mertelu, Gendangsari, Gunung Kidul, Yogyakarta menjadi salah satu wilayah program Kuliah Kerja Nyata UAD dengan tema Peningkatan Pemberdayaan Kesehatan Masyarakat Menuju Desa Siaga. Program kegiatan dilakukan melalui metode penyuluhan dan pelatihan, serta pendampingan untuk meningkatkan kesadaran akan kesehatan. Hasil dari kegiatan ini yaitu terlaksana kegiatan penyuluhan PHBS, Pencegahan Leptospirosis, TOGA, dan program rutin kesehatan. Dampak dari program pemberdayaan bidang kesehatan adalah berubahnya perilaku warga dan meningkatnya kesadaran dalam menjaga kesehatan sebagai salah satu modal dalam meningkatkan kesejahteraan
PERANCANGAN DAN PENDAMPINGAN PENGELOLAAN SURAT BERBASIS KEBUTUHAN
Authors: Suryani Nanik , Ismiyati Ismiyati , Jaenudin Ahmad
Published: May 2022

The aim of devotion is (1) designing the letter management basedon need analysis of school; (2) training in implementing the result of design; (3) arranging the classification of archive; and (4) implementing the electronic letter management. The main priority of devotion is providing knowledge about handling of incoming and outgoing letter. In addition, the dedication is realizing to create the good administration for school, so that it can be supporting the accountability of school with authentic document. The implementation of devotion through socialization and training about management of letter based on need analysis. To overcome the obstacles of implemention in handling letter, we would evaluate from mentoring activity.
PENINGKATAN KAPASITAS PROFESIONALISME GURU MATEMATIKA SMA/SMK/MA MUHAMMADIYAH SE-KOTA YOGYAKARTA
Authors: Purwadi Joko , Thobirin Aris
Published: May 2022

Profesionalisme dalam mendidik siswa sangat diperlukan untuk kemajuan suatu bangsa, secara khusus pada mata pelajaran matematika di tingkat SMA/SMK/MA Muhammadiyah. Guru berhak memperoleh kesempatan untuk meningkatkan kompetensi, memperoleh pelatihan, dan mengembangkan profesi dalam bidangnya. Dari sisi kewajiban, guru wajib memiliki kualifikasi akademik, kompetensi, sertifikat pendidik, sehat jasmani dan rohani, serta memiliki kemampuan untuk mewujudkan tujuan pendidikan nasional. Salah satu upaya dalam menyetarakan dan menilai kinerja guru dalam hal keprofesionalan, pemerintah menggelar Uji Kompetensi Guru (UKG), yang bertujuan untuk pemetaan kompetensi. Untuk mencapai keprofesionalan guru dan kelulusan, diperlukan pelatihan kepada guru sebelum melakukan UKG. Pelatihan ini diselenggarakan dalam waktu 2 hari dengan materi Kalkulus dan Statistika. Peserta pada kegiatan ini berasal dari 12 Sekolah di lingkungan Muhammadiyah se-Kota Yogyakarta dan bekerjasama dengan Majelis Pendidikan Dasar dan Menengah PDM Yogyakarta.
PENDAMPINGAN KAMPANYE DIGITAL MELALUI WEBSITE DAN SOSIAL MEDIA KEPADA KAWAN KASIH TUMBUH
Authors: Nastiti Putri , Wibisono Y Priadi
Published: May 2022

Papua merupakan salah satu daerah di Indonesia yang termasuk dalam Indonesia bagian Timur. Ada berbagai sektor di Papua yang menjadi perhatian pemerintah, salah satunya adalah sektor pendidikan. Pemerintah Indonesia mengalokasikan dana APBN sebesar 20% untuk pendidikan di Papua. Terdapat 62 juta siswa di Indonesia, sayangnya angka sebesar itu tidak menjamin penyebaran dan kualitas pendidikan yang merata ke seluruh wilayah Nusantara. Fakta yang diungkap oleh United Nations Children's Fund (UNICEF) menunjukkan bahwa 30% siswa Papua tidak menyelesaikan SD dan SMP. Hal ini yang melatarbelakangi komunitas Kawan Kasih Tumbuh untuk terjun langsung ke bumi Papua, dengan semangat memajukan pendidikan khususnya di Kabupaten Yahukimo. Penulis memberikan solusi untuk mengkampanyekan Program Kawan Kasih Tumbuh secara digital. Kampanye adalah upaya yang ditujukan untuk menciptakan perubahan dan dampak tertentu dalam kehidupan bermasyarakat. Kampanye ini bertujuan untuk memberikan dampak berupa bantuan, baik berupa donasi maupun hal lainnya untuk kemajuan pendidikan anak-anak di Papua. Kampanye digital untuk donasi ini nantinya akan ditujukan untuk pendidikan di daerah Papua melalui para relawan dari Komunitas Kawan Kasih Tumbuh.
Secondary hypertension and its treatment in cats
Authors: Geddes Rebecca
Published: May 2022

Secondary hypertension caused by an underlying disease is common in older cats, especially in those with chronic kidney disease and/or hyperthyroidism. Systolic blood pressure should be measured whenever an associated disease is diagnosed and persistent systolic blood pressure >160mmHg should prompt treatment to prevent or reverse target organ damage. Amlodipine and telmisartan are licensed in the UK to treat feline hypertension and both drugs have been evaluated in prospective randomised placebo-controlled clinical trials in hypertensive cats with systolic blood pressure of 160–200mmHg that did not have evidence of target organ damage. Initial reductions of 20–30mmHg can be expected with either medication, and cats should be re-evaluated after 14 days and dose adjustments made as required. No studies have compared the performance of one drug against the other and either medication should be selected as the first-line treatment for feline hypertension. At present, there are more data in the literature to support the use of amlodipine in cats with severe hypertension (systolic blood pressure >200mmHg), or with evidence of ocular or neurological target organ damage.
UK parasite risk factors and control challenges
Authors: Bagster Amy , Elsheikha Hany
Published: May 2022

Endemic and emerging parasites pose a risk to companion animals and their owners. Emerging parasites can also impose a significant public health burden. The discovery of new parasites, the insurgence of endemic ones, and the emergence of new information has made managing parasitic diseases a topical subject for veterinarians, who are now starting to see more patients with these diseases. Better understanding of the extent and burden of parasites on animals and humans is essential for control interventions. This article discusses the known risk factors of UK parasites in the current literature, use of parasiticides in small animal medicine, known challenges to effective parasite control, risks of parasiticides and current guidelines surrounding their use.
Spatially Distribution of Soil Ultimate Bearing Capacity at Singkil-Aceh Based on a Static Cone Penetration Test
Authors: Yunita Halida , Al Huda Nafisah , Sundary Devi , Gunawan Hendra , Sungkar Munira , Setiawan Bambang , Sartika Dewi
Published: May 2022

The Singkil Sub-district of Aceh Singkil District comprises alluvium deposits with a relatively low ultimate bearing capacity. The ultimate bearing capacity of the soil is closely related to the safety of a building. The important thing related to estimating the ultimate bearing capacity of the soil is in-situ soil investigation. This study aims to estimate the spatial distribution of soil ultimate bearing capacity using field test data in the Singkil Sub-district. Estimating ultimate bearing capacity is useful to provide an initial picture for various planning and infrastructure development activities in the study area. Twenty CPT in-situ tests have been obtained from various field works in Aceh Singkil Regency. Field data analysis, based on empirical methods, was carried out to obtain the value of the ultimate bearing capacity of the soil at the test location. Then, the estimated distribution of the maximum bearing capacity obtained was carried out. The zoning map of the distribution of soil ultimate bearing capacity in the study was developed from this research. This map can be used as a form or effort of disaster mitigation by various stakeholders involved in planning and building various infrastructure facilities in the Singkil Sub-district
Functional Group Structure of Bamboo and Pine Wood Biochar Due to Differences in Pyrolysis Temperature
Authors: Darusman Darusman , Syakur Syakur , Kurniasih Eka , Puspita Vera , Zaitun Zaitun
Published: May 2022

The quality of biochar produced through the pyrolysis process depends on the combustion temperature, duration of combustion, and the raw materials used. Biochar is a carbon-rich product resulting from the thermal decomposition of organic matter. Biochar from bamboo and pinewood was produced at 400℃ and 800℃ using a closed chamber where the temperature could be set. Biochar is made through carbonization with pyrolysis. This study aimed to find out the functional group characteristics of two types of raw materials, bamboo and pine wood. This research was conducted at the Environmental Soil Physics Laboratory, Universitas Syiah Kuala. Two types of feedstocks, bamboo, and pinewood, were used as sample experiments. The feedstocks were burned inside a closed chamber with no oxygen present. (Thermo scientific thermolyne F4820-33). The temperature was at 400℃ and 800℃, and a burning time of four hours. Fourier Transform Infra-Red (FTIR) was used to characterize the functional groups of biochar tested. Our research showed biochar from pinewood burned at a temperature of 400℃ gave the characteristics of the functional groups OH, CH, and C=O with strong intensity. It indicates that there was decomposition of organic matter into organic compounds taking place
Comparing Outlier Detection Methods using Boxplot Generalized Extreme Studentized Deviate and Sequential Fences
Authors: Fitrianto Anwar , Wan Muhamad Wan Zuki Azman , Kriswan Suliana , Susetyo Budi
Published: May 2022

Outliers identification is essential in data analysis since it can make wrong inferential statistics. This study aimed to compare the performance of Boxplot, Generalized Extreme Studentized Deviate (Generalized ESD), and Sequential Fences method in identifying outliers. A published dataset was used in the study. Based on preliminary outlier identification, the data did not contain outliers. Each outlier detection method's performance was evaluated by contaminating the original data with few outliers. The contaminations were conducted by replacing the two smallest and largest observations with outliers. The analysis was conducted using SAS version 9.2 for both original and contaminated data. We found that Sequential Fences have outstanding performance in identifying outliers compared to Boxplot and Generalized ESD.
Construction of Hierarchical CuCo2O4-Ni(OH)2 Core-Shell Nanowire Arrays for High-Performance Pseudocapacitors
Authors: Azmy Ilham , Wang Jun
Published: May 2022

The hierarchical CuCo2O4-Ni(OH)2 core-shell nanowire arrays on Ni foam were fabricated using facile and cost-effective two-step hydrothermal synthesis. The growth of CuCo2O4 nanowires was developed on Ni foam as the apposite basis of the conductive scaffold, and the ultrathin Ni(OH)2 nanowires were subsequently immobilized to form CuCo2O4-Ni(OH)2 core-shell nanowire arrays (NWAs). The prepared materials were further characterized in structural, morphological, and electrochemical properties. The obtained CuCo2O4-Ni(OH)2 pseudocapacitor electrode, incorporated by unique core-shell heterostructures nanowire arrays, exhibited great specific capacitance of 1201.67 F g-1 at 1 mA g-1, which is much higher than pristine CuCo2O4 nanowire of 638.89 F g-1 at 1 mA g-1. Simultaneously, it also has a high power density of 5.56 kW kg-1 at an energy density of 73.33 Wh kg-1 and good long-term cycling performance (~84 capacitance retention after 1000 cycles). The improved morphological and structural properties have substantiated the CuCo2O4-Ni(OH)2 core-shell nanowire arrays properties owing to higher surface active area and richer redox activity for boosting the electrochemical properties.
Second harmonic generation microscopy of otoconia
Authors: Brittain Kennedy , Harvey MacAulay , Cisek Richard , Pillai Saranyan , Christie Sean D , Tokarz Danielle
Published: May 2022

The origin of second harmonic generation (SHG) signal in otoconia was investigated. SHG signal intensity from otoconia was compared to pure calcite crystals, given calcite is the primary component of otoconia and is known to emit surface SHG. The SHG intensity from calcite was found to be ∼41× weaker than the SHG intensity from otoconia signifying that the SHG signal from otoconia is likely generated from the organic matrix. Furthermore, the SHG intensity from otoconia increased when treated with a chelating agent known to dissolve calcite which confirms that calcite is not the source of SHG. Additionally, polarization-resolved SHG microscopy imaging revealed that the arrangement of the SHG emitters is radial and can form highly ordered domains.
Topological Kerr effect in the graphene family materials
Authors: Shah Muzamil , Anwar Muhammad Sabieh
Published: May 2022

Materials belonging to the graphene family are two-dimensional staggered monolayers that undergo topological phase transitions under the influence of an external electric field or off-resonant optical field. Inspired by the interplay between topological matter and the helicity of photons, we investigate various topological quantum phases of the graphene family materials (GFMs), when subject to an external electric field and irradiated by off-resonant light. Using the Kubo formalism, we derive analytic expressions of the valley and spin-resolved conductivities of silicene. We then show that the topological quantum phase transitions can be modulated by an external electric field or irradiating circularly polarized light on the surface. Based on a general beam propagation model, we theoretically investigate the transitional Kerr rotations in silicene in different phases. Our results identify topological phases where Kerr rotations and ellipticity can be maximized. We believe that our results are helpful for developing novel practical devices based on the Kerr effect of silicene.
Metasurface-based Fourier lens fed by compact plasmonic optical antennas for wide-angle beam steering
Authors: Zhou Guangzhu , Qu Shi-Wei , Chen Baojie , Zeng Yuansong , Chan Chi Hou
Published: May 2022

A Fourier lens can perform the Fourier transform of an incident wavefront at the focal plane. This paper reports a metasurface-based Fourier lens fed by compact plasmonic optical antennas for wide-angle beam steering. The metasurface, composed of six elements with different configurations covering the 2π phase range, features a large field-of-view (FOV) of ±50°. A novel plasmonic optical antenna for broadside radiation is then designed as the feed source of the metasurface. The proposed antenna has ultra-compact size of 0.77λ × 1.4λ, and achieves a high directivity of 9.6 dB and radiation efficiency of over 80% at the wavelength of 1550 nm. Full-wave simulations are carried out to evaluate the performances of the designed metasurface-assisted beam steering device. The results show that this device can achieve a maximum directivity of 21.5 dB at broadside radiation. Compared to conventional Yagi-Uda antenna feed, a directivity enhancement of about 2.7 dB can be obtained, exhibiting a great superiority of the proposed feed antenna. In addition, a large beam steering range of ±50° can be achieved with an acceptable gain drop of 2.83 dB. With the advantages of wide beam steering range, good radiation characteristics, small footprint, and ease of integration, the proposed metasurface-assisted beam steering device would be a promising candidate for integrated photonic applications, including wireless optical communications, light detection and ranging, and augmented reality.
Deep learning-enabled image content-adaptive field sequential color LCDs with mini-LED backlight
Authors: Zou Guowei , Wang Zeyu , Liu Yutong , Li Juanli , Liu Xingyun , Liu Jiahui , Yang Bo-Ru , Qin Zong
Published: May 2022

The mini-LED as the backlight of field sequential color LCD (FSC-LCD) enables high contrast, thin volume, and theoretically tripled light efficiency and resolution. However, color breakup (CBU) induced by a relative speed between an observer and the display severely limits the application of FSC-LCDs. Several driving algorithms have been proposed for CBU suppression, but their performance depends on image content. Moreover, their performance plateaus with increasing image segment number, preventing taking advantage of the massive segments introduced by mini-LEDs. Therefore, this study proposes an image content-adaptive driving algorithm for mini-LED FSC-LCDs. Deep learning-based image classification accurately determines the best FSC algorithm with the lowest CBU. In addition, the algorithm is heterogeneous that the image classification is independently performed in each segment, guaranteeing minimized CBU in all segments. We perform objective and subjective validation. Compared with the currently best algorithm, the proposed algorithm improves the performance in suppressing CBU by more than 20% using two evaluation metrics, supported by experiment-based subjective evaluation. Mini-LED FSC-LCDs driven by the proposed algorithm with outstanding CBU suppression can be ideal for display systems requiring high brightness and high resolution, such as head-up displays, virtual reality, and augmented reality displays.