bluuebunny/crossref_metadata_2025 huggingface dataset:
Infância e medicalização da vida: uma análise sobre a produção diagnóstica e seus nexos com os processos de escolarização
Authors: Oliveira Aniê Coutinho de , Silva Carla Maciel da , Baptista Claudio Roberto
Published: December 2020

Nas últimas décadas tem ocorrido uma ampliação dos diagnósticos referentes aos transtornos e deficiências, principalmente no que tange ao público infantil. Esse aumento associa-se a modificações de critérios diagnósticos, ao avanço da produção diagnóstica no contexto escolar e à influência de interesses associados aos conglomerados da produção farmacológica descritos por estudiosos dessa temática. Este artigo se propõe a analisar a medicalização da vida infantil e a produção diagnóstica que se vincula aos processos de escolarização. Para tanto, apresenta-se um breve histórico a respeito da constituição do DSM, em sintonia com o debate acadêmico contemporâneo. Busca-se discutir como os engendramentos desse manual contribuem com a produção do que se compreende por inflação diagnóstica. A análise considera o processo de medicalização da vida no contexto infantil, com base em procedimentos que tendem a reduzir os fenômenos humanos a manifestações comportamentais que poderiam ser codificadas em dinâmicas que reafirmam o sujeito como centro da falta a ser corrigida.
Políticas de avaliação externa e a medicalização da educação: dos sentidos do “não aprender” até o “não ensinar”
Authors: Souza Vilma Aparecida de , Richter Leonice Matilde , Silva Lázara Cristina da
Published: December 2020

Neste artigo, objetivamos analisar as políticas de avaliação externa e os efeitos concernentes ao “não aprender” e ao “não ensinar” como marcas da culpabilização e medicalização da educação. Por meio de um estudo bibliográfico, abordamos os constructos teóricos-conceituais que confrontam a lógica classificatória das avaliações no âmbito das políticas. Como procedimentos metodológicos do campo empírico, realizamos entrevistas dialogadas com professores de um município mineiro. Evidenciamos os sentidos e efeitos precípuos das políticas de avaliação marcadas pelo modus operandi neoliberal que afeta a organização do trabalho pedagógico, os estudantes e os docentes que são forçados a se enquadrarem em resultados e padrões eivados de interesses do mercado. Nesse caso, os sujeitos que não se atentam às expectativas quantitativas são culpabilizados e submetidos a dispositivos de poder que procuram enquadrá-los nos padrões definidos como normais e/ou ideais, ao explicitarem a lógica medicalizante.
Approach in Improving Potency and Selectivity of Kinase Inhibitors: Allosteric Kinase Inhibitors
Authors: Wei Shangfei , Zhao Tianming , Wang Jie , Zhai Xin
Published: December 2020

Allostery is an efficient and particular regulatory mechanism to regulate protein functions.
Different from conserved orthosteric sites, allosteric sites have a distinctive functional mechanism to
form the complex regulatory network. In drug discovery, kinase inhibitors targeting the allosteric
pockets have received extensive attention for the advantages of high selectivity and low toxicity. The
approval of trametinib as the first allosteric inhibitor validated that allosteric inhibitors could be used
as effective therapeutic drugs for the treatment of diseases. To date, a wide range of allosteric inhibitors
have been identified. In this perspective, we outline different binding modes and potential advantages
of allosteric inhibitors. In the meantime, the research processes of typical and novel allosteric
inhibitors are described briefly in terms of structure-activity relationships, ligand-protein interactions,
and in vitro and in vivo activity. Additionally, challenges, as well as opportunities, are also presented.
Repurposed Antiviral Drugs for the Treatment of COVID-19: Syntheses, Mechanism of Infection and Clinical Trials
Authors: Paul Subha Sankar , Biswas Goutam
Published: December 2020

COVID-19 is a public health emergency of international concern. Although considerable
knowledge has been acquired with time about the viral mechanism of infection and mode of replication,
yet no specific drugs or vaccines have been discovered against SARS-CoV-2 to date. There are
few small molecule antiviral drugs like Remdesivir and Favipiravir, which have shown promising results
in different advanced stages of clinical trials. Chloroquinine, Hydroxychloroquine, and Lopinavir-
Ritonavir combination, although initially were hypothesized to be effective against SARSCoV-
2, are now discontinued from the solidarity clinical trials. This review provides a brief description
of their chemical syntheses along with their mode of action, and clinical trial results available on
Google and in different peer-reviewed journals till 24th October 2020.
An Efficacy and Safety Study of Remogliflozin in Obese Indian Type 2 Diabetes Mellitus Patients Who Were Inadequately Controlled on Insulin Glargine Plus other Oral Hypoglycemic Agents
Authors: Shankar Anand
Published: December 2020

Aim & Objective:

The objective of this retrospective study was to investigate the efficacy of adding remogliflozin to current insulin glargine plus two oral drug i.e. metformin and teneligliptin therapy in poorly controlled Indian type 2 diabetes.

Material and Methods:

173 study participants were initially selected from patient database who continued on their insulin glargine or received an increased dose of insulin glargine along with other OHA based therapy (Group A) and 187 were selected who had received remogliflozin (100 mg BD) (Group B) in addition to insulin glargine along with other OHA based therapy. Glycated haemoglobin (HbA1c), total daily insulin dose, body weight, and the number of hypoglycemic events were recorded at weeks 0, 12 and 24.

Result:

During the study, mean values of HbA1c, FBG and P2BG were significantly reduced in both groups. Insulin requirements decreased from 45.8 ± 16.7 IU/day to 38.5 ± 13.5 IU/day (P < 0.001) and at week 24 even further decreased to 29.5 ± 14.5 IU/Day . Twenty three patients in group B were able to cease insulin treatment altogether after 24 week treatment. It has been observed to attain tight blood glucose control we need to increase insulin dose in group A from 45.5 ± 16.5 IU/Day to 51.5 ± 14.5 at week 12 (P<0.01) and which further increased to 53.8 ± 12.8 IU/Day at week 24 (P<0.01). Adding remogliflozin showed significant effect on blood pressure (P < 0.001) and weight reduction (P < 0.001). It has been observed that 38% patients has achieves targeted HbA1c (≤7%) in group B where it was 22% in group A.

Conclusion:

Results demonstrate that in uncontrolled T2DM patients remogliflozin 100 mg BD can successfully lay a foundation for prolonged good glycemic control. Early addition of remogliflozin with insulin glargine plus OHAs may be an alternative compare to intensive up titration of insulin daily dose in people with uncontrolled T2DM. Clinical Trial Registration Number: A 2358
Garcinia mangostana Shell and Tradescantia spathacea Leaf Extract- Mediated One-pot Synthesis of Silver Nanoparticles with Effective Antifungal Properties
Authors: Le Ngoc Thuy Trang , Thi Thai Thanh Hoang , Ching Yern Chee , Nguyen Ngoc Hoi , Nguyen Dong Yen Pham , Truong Quynh Mong , Nguyen Dai Hai
Published: December 2020

Background:

The feasibility of plant extracts for metallic nanoparticle fabrication has
been demonstrated. Each plant species impacts differently on formed nanoparticles, thus specific
plants need to be explored in detail.

Objective:

Continuing the fabrication of nanoparticles using green method, Garcinia mangostana
shell and Tradescantia spathacea leaf extract are exploited as reducing sources to form two types of
silver nanoparticles (GMS-AgNPs and TSL-AgNPs) less than 50 nm.

Methods:

Structural characterization of GMS-AgNPs and TSL-AgNPs was performed by ultravioletvisible
spectrophotometry (UV-vis), Fourier transform infrared spectroscopy (FTIR), X-ray energy
dispersive spectrometer (EDAX), scanning electron microscopy (SEM) and transmission electron
microscopy (TEM). Antifungal tests of GMS-AgNPs and TSL-AgNPs were performed with Aspergillus
niger, Aspergillus flavus, and Fusarium oxysporum.

Results:

UV-vis spectra with the 440-nm peak demonstrate the silver nanoparticle formation. FTIR
analysis shows the GMS-AgNPs and TSL-AgNPs modified by organic functional groups. The SEM
and TEM images indicate that the GMS-AgNPs are spherical shaped with rough edged, while the
TSL-AgNPs are spherical shape with smooth surface. The GMS-AgNP average size (15.8 nm) is
smaller than TSL-AgNP (22.4 nm). In addition, antifungal tests using Aspergillus niger, Aspergillus
flavus, and Fusarium oxysporum reveal that GMS-AgNPs and TSL-AgNPs can significantly inhibit
the proliferation of these fungal strains.

Conclusion:

Garcinia mangostana shell and Tradescantia spathacea leaf extract as renewable and
eco-friendly resources playing a dual role for nanoparticle biosynthesis create GMS-AgNPs and
TSL-AgNPs with high antifungal efficiency for biomedical or agricultural applications.
Research Status of Microwave-assisted Reduction Technology of Pyrolusite
Authors: Qiannan Li , Yeqing Ling , Hewen Zheng , Zhi Yang
Published: December 2020

Manganese ore is an important metallurgical raw material that holds an important strategic
position in the national economy of China. However, the grade of manganese ore in the country
is mostly low, and the utilization efficiency of low-grade manganese ore resources is low, which seriously
restricts the healthy and stable development of China’s metallurgical industry. As a new
green heating method, microwave is expected to address the problems of conventional methods
and realize the effective utilization of low-grade manganese ore. In this paper, the research status
of the microwave composite reduction of pyrolusite in recent years is reviewed. Microwave plays
an important role in metallurgy, and it is the current direction pursued to improve the research level
of microwave heating and extend it to actual industrial processes.
A Review of Minimum Quantity Lubrication (MQL) Based on Bibliometry
Authors: Gaurav Gaurav , Sharma Abhay , Dangayach Govind Sharan , Meena Makkhan Lal
Published: December 2020

Background:

Minimum quantity lubrication (MQL) is one of the most promising machining
techniques that can yield a reduction in consumption of cutting fluid by more than 90 %
while ensuring the surface quality and tool life. The significance of the MQL in machining makes
it imperative to consolidate and analyse the current direction and status of research in MQL.

Objective:

This study aims to assess global research publication trends and hot topics in the field of
MQL among machining processes. The bibliometric and descriptive analysis are the tools that the
investigation aims to use for the data analysis of related literature collected from Scopus databases.

Methods:

Various performance parameters are extracted, such as document types and languages of
publication, annual scientific production, total documents, total citations, and citations per article.
The top 20 of the most relevant and productive sources, authors, affiliations, countries, word cloud,
and word dynamics are assessed. The graphical visualisation of the bibliometric data is presented
in terms of bibliographic coupling, citation, and co-citation network.

Results:

The investigation reveals that the International Journal of Machine Tools and Manufacture
(2611 citations, 31 h-index) is the most productive journal that publishes on MQL. The most
productive institution is the University of Michigan (32 publications), the most cited country is
Germany (1879 citations), and the most productive country in MQL is China (124 publications).
The study shows that ‘Cryogenic Machining’, ‘Sustainable Machining’, ‘Sustainability’, ‘Nanofluid’
and ‘Titanium alloy’ are the most recent keywords and indications of the hot topics and future
research directions in the MQL field.

Conclusion:

The analysis finds that MQL is progressing in publications and emerging with issues
that are strongly associated with the research. This study is expected to help the researchers to find
the most current research areas through the author’s keywords and future research directions in
MQL and thereby expand their research interests.
Validation of Saiful Anwar Clinical Congestion Score in Comparison with NT-proBNP for Prediction of Short-term Outcome in Acute Heart Failure with Reduced Ejection Fraction
Authors: Harold Adrian Liemena , Saifur Rohman Mohammad , Riski Fadlan Muhammad , Tri Tjahjono Cholid , Fuji Rahimah Anna , Kurnianingsih Novi
Published: December 2020

Background : Risk stratification of acute heart failure (AHF) patient during hospital admission utilizing clinical scores emerges as an alternative to standart natriuretic peptide measurement. Development of Saiful Anwar clinical congestion score (SACS) as multivariable predictive model for prediction of short-term outcome in AHF with reduced ejection fraction (AHF-rEF) requires validation in comparison to NT-proBNP. Objective : To validate prognostic value of SACS compare with NT-proBNP in AHF-rEF Method : This single-center, prospective cohort study was held in dr. Saiful Anwar General Hospital during January 2019 to June 2020. From total 89 AHF-rEF patients who admitted to emergency department, were assigned to SACS prospective questionnaire fulfillment and NT-proBNP measurement during first 12-hours since admission. Patients were divided into two groups based on SACS score and NT-proBNP value during admission. 90-days follow up was performed after index hospitalization with outcome of interest i.e all-cause mortality (ACM) and HF-related rehospitalization (HFR). Results : ACM and HFR rate in this study were 16.8% and 22.5%, respectively. SACS ≥6 demonstrated higher ACM and HFR rate during 90-days follow-up compared to SACS <6 (p=0.000; p=0.000, respectively). Performance of SACS ≥6 on admission showed good discriminative power for predicting 90-days ACM and HFR (AUC 0.841, p=0.000; AUC 0.788, p=0.000, respectively) compared to NT-proBNP ≥5000pg/mL (AUC 0.812, p=0.000; AUC 0.819, p=0.000, respectively). Additive value of NT-proBNP ≥5000pg/mL on top of SACS ≥6 increases discriminative power for predicting 90-days ACM and HFR after index hospitalization (AUC 0.836, p=0.000; AUC 0.90, p=0.000, respectively). Conclusion : SACS has demonstrated prognostic value compared to NT-proBNP for prediction of 90-days ACM and HFR after index hospitalization in AHF-rEF patients.
Heterogeneous communication system for technical control and monitoring of energy, industrial, housing and utilities, and agro-industrial facilities
Authors: Shubarev V. A. , Myakochin Yu. O. , Gusarov A. A.
Published: December 2020

Problem statement. Automated systems for monitoring and accounting of energy resources are increasingly used in large companies and small-scale production. Specialists often face the problem of installing sensors and receiving data in rooms with thick reinforced concrete and brick walls, where it is impossible to establish reliable radio communication, and the installation of additional cables is expensive. In such conditions, heterogeneous communication systems, in which different technologies can be used for communication, prove themselves well.

Objective. Determine the optimal technology for heterogeneous communication systems for installing an automated system for monitoring and accounting of energy resources in certain conditions and develop technical proposals.

Results. A simulation of the physical level of the communication system was performed using a PLC-G3 protocol. The energy characteristics were modeled and evaluated using 6LoWPAN technology. Technical proposals for creating technical means of the heterogeneous communication system are developed, the architecture of technical means and the structure of heterogeneous communication system are proposed.

Practical significance. An automated system for monitoring and accounting of energy resources based on a heterogeneous sensor communication system provides regular collection of accurate information about energy resources at all stages of their movement – from input at the facility to each of the end points of consumption, provides access to the collected data for analyzing the state of the system as a whole, and allows operational control of the actuators of metering and control devices.
Research of electrical characteristics of increased uniformity LAN-cables
Authors: Bulkhin A. K. , Klyuchnikov V. F. , Bannov V. V. , Popov V. B.
Published: December 2020

Formulation of the problem. At present, symmetric LAN cables are widely used in structured cabling systems (SCS) and fixed broadband access (BBA) networks in the world and in Russia. Practical experience of using LAN cables on real broadband access networks shows that high-quality transmission can only be achieved using high-quality highly uniform cables.

Objective. Study of the dependence of the quality of LAN-cables on technological equipment and the quality of materials, which provide increased cable uniformity.

Results. Based on the experimental studies carried out with the use of a modern measuring system, the main electrical characteristics of the transmission and the mutual influence of the most popular four-pair LAN-cable of the 5e category of the U/UTP4×2×0.52 type in the frequency range up to 100 MHz are determined. It is shown that to ensure high and stable transmission characteristics and mutual influence, modern technological equipment must be equipped with cable quality parameters automatic control systems and it is necessary to choose reliable suppliers when using domestic production materials.

Practical significance. For the effective practical use of LAN cables on fixed broadband access networks and in SCS, it is very important to have high stability of electrical characteristics and their compliance with rather high established standards. This is possible only by ensuring high geometric and structural homogeneity of the structural elements of LAN cables.
Comprehensive solution for onboard fiber-optic information networks
Authors: Andreev V. A. , Bourdine A. V. , Burdin V. A.
Published: December 2020

Problem statement. In recent years, the problem of replacing copper-core fiber-optic cables has become particularly relevant. This is due to two factors: first, the prospect of introducing unmanned vehicles and the development of electromagnetic microwave weapons that can disable electronic equipment for almost any target at a distance of 10 km or more, and second, the growing need to reduce the delay of transmitted signals on the network and increase the volume of information transmitted in these networks. The article describes the construction of onboard cable networks using fiberoptic cables. The advantages and disadvantages of fiber-optic based onboard networks are described.

Objective. Development of solutions for the use of fiber-optic communication cables in onboard information networks that provide high technology for laying optical cables, the required speed of information transmission, ease of operation and modernization of information networks.

Results. A comprehensive solution for building onboard information networks based on fiber-optic cables having an increased core diameter and an optimized refractive index profile in pipelines using pneumatic laying technology is proposed.

Practical implications. The proposed integrated solution for onboard fiber-optic information networks, including a method for onboard laying optical cables, the use of specially developed optical fiber with an increased core diameter and reduced differential modal delay, and the development of modular telecommunications equipment, allows meeting the requirements for onboard networks to ensure reliability and safety, economic efficiency, reduce labor intensity, and ease of maintenance, components dismantling and replacement.
Relationship Between Diabetes, Stress, and Self-Management to Inform Chronic Disease Product Development: Retrospective Cross-Sectional Study
Authors: Yu Jessica S , Xu Tong , James Roberta A , Lu Wei , Hoffman Julia E
Published: December 2020

Background

Technology is rapidly advancing our understanding of how people with diabetes mellitus experience stress.

Objective

The aim of this study was to explore the relationship between stress and sequelae of diabetes mellitus within a unique data set composed of adults enrolled in a digital diabetes management program, Livongo, in order to inform intervention and product development.

Methods

Participants included 3263 adults under age 65 who were diagnosed with diabetes mellitus and had access to Livongo through their employer between June 2015 and August 2018. Data were collected at time of enrollment and 12 months thereafter, which included demographic information, glycemic control, presence of stress, diabetes distress, diabetes empowerment, behavioral health diagnosis, and utilization of behavioral health-related medication and services. Analysis of variance and chi-square tests compared variables across groups that were based on presence of stress and behavioral health diagnosis or utilization.

Results

Fifty-five percent of participants (1808/3263) reported stress at the time of at least 1 blood glucose reading. Fifty-two percent of participants (940/1808) also received at least 1 behavioral health diagnosis or intervention. Compared to their peers, participants with stress reported greater diabetes distress, lower diabetes empowerment, greater insulin use, and poorer glycemic control. Participants with stress and a behavioral health diagnosis/utilization additionally had higher body mass index and duration of illness.

Conclusions

Stress among people with diabetes mellitus is associated with reduced emotional and physical health. Digital products that focus on the whole person by offering both diabetes mellitus self-management tools and behavioral health skills and support can help improve disease-specific and psychosocial outcomes.
Physiological Responses and User Feedback on a Gameful Breathing Training App: Within-Subject Experiment
Authors: Lukic Yanick Xavier , Shih Chen-Hsuan (Iris) , Hernandez Reguera Alvaro , Cotti Amanda , Fleisch Elgar , Kowatsch Tobias
Published: December 2020

Background

Slow-paced breathing training (6 breaths per minute [BPM]) improves physiological and psychological well-being by inducing relaxation characterized by increased heart rate variability (HRV). However, classic breathing training has a limited target group, and retention rates are very low. Although a gameful approach may help overcome these challenges, it is crucial to enable breathing training in a scalable context (eg, smartphone only) and ensure that they remain effective. However, despite the health benefits, no validated mobile gameful breathing training featuring a biofeedback component based on breathing seems to exist.

Objective

This study aims to describe the design choices and their implementation in a concrete mobile gameful breathing training app. Furthermore, it aims to deliver an initial validation of the efficacy of the resulting app.

Methods

Previous work was used to derive informed design choices, which, in turn, were applied to build the gameful breathing training app Breeze. In a pretest (n=3), design weaknesses in Breeze were identified, and Breeze was adjusted accordingly. The app was then evaluated in a pilot study (n=16). To ascertain that the effectiveness was maintained, recordings of breathing rates and HRV-derived measures (eg, root mean square of the successive differences [RMSSDs]) were collected. We compared 3 stages: baseline, standard breathing training deployed on a smartphone, and Breeze.

Results

Overall, 5 design choices were made: use of cool colors, natural settings, tightly incorporated game elements, game mechanics reflecting physiological measures, and a light narrative and progression model. Breeze was effective, as it resulted in a slow-paced breathing rate of 6 BPM, which, in turn, resulted in significantly increased HRV measures compared with baseline (P<.001 for RMSSD). In general, the app was perceived positively by the participants. However, some criticized the somewhat weaker clarity of the breathing instructions when compared with a standard breathing training app.

Conclusions

The implemented breathing training app Breeze maintained its efficacy despite the use of game elements. Moreover, the app was positively perceived by participants although there was room for improvement.
The Use of Telehealth Technology to Support Health Coaching for Older Adults: Literature Review
Authors: Markert Carl , Sasangohar Farzan , Mortazavi Bobak J , Fields Sherecce
Published: December 2020

Background

Health coaching is an intervention process for driving behavior change through goal-setting, education, encouragement, and feedback on health-related behaviors. Telehealth systems that include health coaching and remote monitoring are making inroads in managing chronic conditions and may be especially suited for older populations.

Objective

This literature review aimed to investigate the current status of health coaching interventions incorporating telehealth technology and the associated effectiveness of this intervention to deliver health care with an emphasis on older adults (aged 65 and older).

Methods

A literature review was conducted to identify the research conducted on health coaching combined with remote monitoring for delivering health care to older adults. The Ovid MEDLINE and CINAHL databases were queried using a combination of relevant search terms (including middle aged, aged, older adult, elderly, health coaching, and wellness coaching). The search retrieved 196 papers published from January 2010 to September 2019 in English. Following a systematic review process, the titles and abstracts of the papers retrieved were screened for applicability to health coaching for older adults to define a subset for further review. Papers were excluded if the studied population did not include older adults. The full text of the 42 papers in this subset was then reviewed, and 13 papers related to health coaching combined with remote monitoring for older adults were included in this review.

Results

Of the 13 studies reviewed, 10 found coaching supported by telehealth technology to provide effective outcomes. Effectiveness outcomes assessed in the studies included hospital admissions/re-admissions, mortality, hemoglobin A1c (HbA1c) level, body weight, blood pressure, physical activity level, fatigue, quality of life, and user acceptance of the coaching program and technology.

Conclusions

Telehealth systems that include health coaching have been implemented in older populations as a viable intervention method for managing chronic conditions with mixed results. Health coaching combined with telehealth may be an effective solution for providing health care to older adults. However, health coaching is predominantly performed by human coaches with limited use of technology to augment or replace the human coach. The opportunity exists to expand health coaching to include automated coaching.
Using a Commercially Available App for the Self-Management of Hypertension: Acceptance and Usability Study in Saudi Arabia
Authors: Alessa Tourkiah , S Hawley Mark , Alsulamy Nouf , de Witte Luc
Published: December 2020

Background

The use of smartphone apps to assist in the self-management of hypertension is becoming increasingly common, but few commercially available apps have the potential to be effective along with adequate security and privacy measures in place. In a previous study, we identified 5 apps that are potentially effective and safe, and based on the preferences of doctors and patients, one (Cora Health) was selected as the most suitable app for use in a Saudi context. However, there is currently no evidence of its usability and acceptance among potential users. Indeed, there has been little research into the usability and acceptance of hypertension apps in general, and less research considers this in the Gulf Region.

Objective

This study aims to evaluate the acceptance and usability of the selected app in the Saudi context.

Methods

This study used a mixed methods approach with 2 studies: a usability test involving patients in a controlled setting performing predefined tasks and a real-world usability study where patients used the app for 4 weeks. In the usability test, participants were asked to think aloud while performing the tasks, and an observer recorded the number of tasks they completed. At the end of the real-world pilot study, participants were interviewed, and the mHealth App Usability Questionnaire was completed. Descriptive statistics were used to analyze quantitative data, and thematic analysis was used to analyze qualitative data.

Results

In total, 10 patients completed study 1. The study found that app usability was moderate and that participants needed some familiarization time before they could use the app proficiently. Some usability issues were revealed, related to app accessibility and navigation, and a few tasks remained uncompleted by most people. A total of 20 patients completed study 2, with a mean age of 51.6 (SD 11.7) years. Study 2 found that the app was generally acceptable and easy to use, with some similar usability issues identified. Participants stressed the importance of practice and training to use it more easily and proficiently. Participants had a good engagement level with 48% retention at the end of study 2, with most participants’ engagement being classed as meaningful. The most recorded data were blood pressure, followed by stress and medication, and the most accessed feature was viewing graphs of data trends.

Conclusions

This study shows that a commercially available app can be usable and acceptable in the self-management of hypertension but also found a considerable number of possibilities for improvement, which needs to be considered in future app development. The results show that there is potential for a commercially available app to be used in large-scale studies of hypertension self-management if suggestions for improvements are addressed.
Дифференциальная лечебная тактика при осложненных метафизарных переломах дистального отдела плечевой кости у детей
Authors: Trutyak I.R. , Obaranets O.V.
Published: December 2020

Цель — оптимизация диагностики и тактики лечения у пострадавших детского возраста с осложненными чрезмыщелковыми и надмыщелковыми переломами плечевой кости с помощью разработанной протокольной схемы оказания медицинской помощи пострадавшим с чрезмыщелковыми и надмыщелковыми переломами плечевой кости. Материалы и методы. В основу нашей работы положен ретроспективный анализ лечения 255 пациентов, лечившихся в Львовской городской детской больнице за период 2013–2017 годы. Результаты. Анализ результатов лечения показал, что в первой группе осложнения отмечались в 21,0 % случаев, а во второй группе — только в 9,1 %. Среди пострадавших первой группы анатомические осложнения отмечались в 38,4 % случаев, а во второй группе их не было вообще. Функциональные осложнения также превалировали в первой группе, они обнаруживались в два раза чаще, чем во второй группе. Период стационарного лечения в первой группе составил 9,2 ± 0,5 суток, во второй — 6,5 ± 0,4 суток. Выводы. Внедрение унифицированной протокольной схемы лечения чрезмыщелковых и надмыщелковых переломов плечевой кости у пациентов детского возраста позволило значительно улучшить как анатомические, так и функциональные результаты лечения пациентов этой категории.
Влияние методов послеоперационного обезболивания на моторную функцию желудочно-кишечного тракта у детей с перитонитом, осложненным интраабдоминальной гипертензией
Authors: Perova-Sharonova V.M.
Published: December 2020

Актуальность. Метод послеоперационного обез­боливания может влиять на скорость восстановления моторной функции желудочно-кишечного тракта, уровень интраабдоминального давления (ИАД) и способствовать развитию интраабдоминальной гипертензии (ИАГ). Цель: исследовать влияние методов послеоперационного обезболивания на моторную функцию кишечника у детей с перитонитом, осложненным ИАГ. Материалы и методы. 115 детей, которым были проведены оперативные вмешательства по поводу аппендикулярного перитонита, рандомизированы на группы в зависимости от метода послеоперационного обезболивания: «Опиоиды» (n = 36, инфузия морфина), «Лидокаин» (n = 40, инфузия лидокаина), «ЭДА» (n = 39, эпидуральная аналгезия). В зависимости от уровня ИАД и наличия органной дисфункции дети каждой группы были разделены на подгруппы: «без ИАГ» (ИАД < 10 мм рт.ст.), «ИАГ» (ИАД > 10 мм рт.ст.) и «АКС» (абдоминальный компартмент-синдром, ИАГ с органной дисфункцией). Всем детям в послеоперационном периоде проводилось измерение уровня ИАД и оценка скорости восстановления моторной функции желудочно-кишечного тракта. Результаты. Во всех подгруппах группы «ЕДА» время до восстановления перистальтики и первых испражнений и объем остатка по назогастральному зонду были статистически значимо меньшими по сравнению с аналогичными показателями в подгруппах группы «Опиоиды» (Р < 0,05). В подгруппах «ИАГ» и «АКС» группы «ЭДА» также было статистически значимо меньшим время до первых испражнений по сравнению с аналогичными показателями в подгруппах группы «Лидокаин» (Р < 0,05). Статистически значимо меньшими были время до восстановления перистальтики и объем остатка по НГЗ во всех подгруппах группы «Лидокаин» по сравнению с аналогичными показателями группы «Опиоиды» (Р < 0,05). Эпизоды повышения ИАД >10 мм рт.ст. значительно чаще встречались у детей в группе «Опиоиды», чем в группах «Лидокаин» и «ЭДА» (Р < 0,05). Количество эпизодов ИАД > 10 мм рт.ст. имело прямую корреляцию с длительностью времени восстановления перистальтики, но сила такой корреляции была выше в группах «Опиоиды» (rs = 0,78; p = 0,001 и rs = 0,76; p = 0,01) и «Лидокаин» (rs = 0,58; p = 0,008 и rs = 0,95; p = 0,01), чем в группе «ЭДА» (rs = 0,39; p = 0,16 и rs = 0,46, p = 0,43). Выводы. ЭДА является оптимальным методом послеоперационного обезболивания у детей с перитонитом, осложненным ИАГ, который приводит к раннему восстановлению моторной функции ЖКТ и предотвращает дальнейший рост ИАД. Инфузия лидокаина может быть использована как альтернативный метод обезболивания. Системная опиоидная аналгезия оказывает негативное влияние на моторику желудочно-кишечного тракта.
Анализ влияния факторов риска на развитие ранней послеоперационной когнитивной дисфункции после отоларингологических операций в условиях общей анестезии с управляемой гипотензией
Authors: Bondar R.A.
Published: December 2020

Актуальность. Актуальность проблемы послеоперационной когнитивной дисфункции (ПОКД) обусловлена высокой частотой ее развития (до 30 % у некардиохирургических пациентов), что влечет за собой ряд психосоматических осложнений с потребностью в последующем социальной адаптации таких пациентов, а также существенными экономическими затратами на лечение этих больных. Цель: выявить и проанализировать факторы риска развития ПОКД после отоларингологических оперативных вмешательств в условиях общей анестезии с управляемой гипотонией. Материалы и методы. В исследование включены 127 больных. Кроме общеклинических и лабораторных данных, проведено до- и послеоперационное тестирование нейрокогнитивных функций, исследованы периоперационные показатели состояния антиоксидантной системы и активности свободнорадикального окисления липидов и протеинов, показатели нейронспецифических и воспалительных маркеров в крови. Результаты. Ранняя ПОКД развилась у 31 (24,4 %) пациента. Различия между пациентами с ПОКД и без ПОКД обнаружены (p < 0,05) между такими показателями: возраст, уровень образования, повторная операция, продолжительность операции, анестезии, управляемой интраоперационной гипотензии, глубина интраоперационной седации, результаты оценки когнитивного статуса после операции, уровни продуктов перекисного окисления белков и липидов, нейронспецифической энолазы, интерлейкина-18 в крови, наличие послеоперационной инфекции. Выводы. Установлено, что независимыми факторами риска развития ранней ПОКД после отоларингологических оперативных вмешательств в условиях общей анестезии с управляемой гипотензией в регрессионном анализе являются: пожилой возраст, низкий уровень образования, повторная операция, продолжительность управляемой интраоперационной гипотензии, глубина интраоперационной седации.
Тиреотоксический периодический паралич: редкий случай
Authors: İncaman Deniz , Salmanoğlu Musa , Tabak Ömür , Kumbasar Abdulbaki
Published: December 2020

Тиреотоксический гипокалиемический периодический паралич является редким наследственным заболеванием, характеризующимся периодической потерей силы мышц. В проведенном исследовании диагностирован периодический гипокалиемический паралич в результате обследования пациента в отделении неотложной помощи. Поскольку этот случай редкий, представлен обзор литературы. 43-летний пациент мужского пола с известной грыжей поясничного диска в анамнезе был доставлен в экстренную службу больницы с жалобой на невозможность движения телом после пробуждения в 6:00 утра. Пациент принимал метимазол в таблетках 12 часов назад из-за жалоб на головную боль. Ужин состоял из продуктов с высоким содержанием углеводов. Клинический осмотр выявил артериальное давление 105/70 мм рт.ст., частоту сердечных сокращений 93 в 1 мин, температуру 36,8 градуса, общую потерю силы в четырех конечностях и тетраплегию. Потери чувствительности, офтальмопатии, тремора не обнаружено, изохорический и световой рефлекс зрачков двусторонний, рефлекс ахиллова сухожилия принят за гипоактивный. Размеры глаз нормальные, щитовидная железа не увеличена. Этот случай оценивали как тиреотоксический периодический паралич, учитывая время начала приступов, особенно после ужина с высоким содержанием углеводов, вызывающим паралич, улучшение симптомов при проведении заместительной терапии, содержание калия в сыворотке крови, тесты функции щитовидной железы и результаты электрокардиограммы. В итоге тиреотоксический периодический паралич следует рассматривать как дифференциальный диагноз у молодых, особенно у пациентов мужского пола, страдающих от двигательного паралича. Определение гормонов щитовидной железы и уровня калия помогает в диагностике.
Interpretasi Anomali Data Gravitasi Daerah Panas Bumi "K51S" Berdasarkan Pemodelan 3D
Authors: Hoerunisa Anis - , Sismanto Sismanto
Published: December 2020

Daerah panas bumi "K51S" merupakan salah satu daerah yang memiliki potensi panas bumi di daerah Sulawesi Tengah. Potensi panas bumi tersebut ditandai dengan adanya manifestasi berupa air panas. Studi lebih lanjut dilakukan untuk mengetahui keberadaan struktur bawah permukaan daerah panas bumi. Salah satu metode yang dapat digunakan dalam eksplorasi panas bumi adalah metode gravitasi. Metode gravitasi merupakan metode geofisika untuk memetakan nilai medan gravitasi bawah permukaan secara lateral. Penelitian ini bertujuan untuk mengetahui pola sebaran anomali residual dan batas kedalaman heat source dan reservoir daerah penelitian, serta memperoleh gambaran struktur geologi bawah permukaan sistem panas bumi daerah penelitian. Data penelitian yang digunakan adalah data sekunder hasil survei lapangan Tim Geosika Pusat Sumber Daya Mineral Batubara dan Panas bumi (PSDMBP) berupa data anomali gravitasi observasi. Data tersebut kemudian dilakukan pengolahan hingga diperoleh data anomali bouger lengkap (ABL), reduksi bidang datar, dan kontinuasi ke atas untuk pemisahan anomali regional dan residual.Hasil anomali residual menunjukan nilai anomali tinggi pada rentang 5-13 mGal yang bersesuaian denganbatuan vulkanik dan anomali rendah berada pada rentang -10-4 mGal tersebar merata di antara anomali tinggi daerah penelitian. Interpretasi pemodelan 3 dimensi menunjukan adanya struktur yang mengontrol sistem panas bumi daerah penelitian adalah sesar Koalarawa dan Towingkoloe. Batuan penyusun sistem panas bumi "K51S" yaitu batuan heat source diinterpretasikan sebagai granit dengan densitas 2,64 { 3,30 gr/cm3 pada kedalaman lebih dari 6 km, batuan reservoir diinterpretasikan sebagai batupasir dengan densitas 1,20-2,34 gr/cm^3 pada kedalaman 1,3 km, batuan caprock diinterpretasikan sebagai batupasir dengan densitas 2,35-2,63 gr/cm^3 pada kedalaman 0,8 km, densitas 2,64-3,30 gr/cm^3 diinterpretasikan sebagai batuan vulkanik, dan endapan permukaan diinterpretasikan sebagai alluvial.
Pengaruh Waktu Pengeringan Sampel Batubara Tarahan Terhadap Nilai Inherent Moisture Dan Nilai Kalor Batubara
Authors: Ardanti Wahyuning Ramadhanta , Asmi Dwi , Dahlia Dahlia
Published: December 2020

Telah dilakukan pengujian tentang pengaruh waktu pengeringan sampel batubara tarahan terhadap nilai inherent moisture dan nilai kalor dengan tujuan untuk menentukan pengaruh waktu pengeringan, menentukan selisih nilai inherent moisture dan nilai terhadap waktu pengeringan dan menentukan hubungan antara nilai inherent moisture dan nilai kalor. Sampel batubara yang digunakan dengan kode sampel TRH 412 sampai dengan TRH 416 dan TRH 430 sampai dengan TRH 434. Pengujian yang dilakukan menggunakan standar BS (British Standar). Perbedaan yang diperoleh nilai inherent moisture dan nilai kalor mengahasilkan 7,11 % dan 727 Cal.gr sehingga didapatkan 1% inherent moisture menghasilkan nilai kalor 102,25 Cal/gr. Hasil pengujian nilai inherent moisture dan nilai kalor pada pengeringan 24 jam didapatkan rata-rata sebesar 11,43% dan 6.236,4 Cal/gr. Pada pengujian dengan pengeringan 3 jam didapatkan hasil nilai inherent moisture dan nilai kalor rata-rata sebesar 18,54% dan 5.509,4 Cal/gr. Waktu pengeringan sangat berpengaruh pada nilai inherent moisture dan nilai kalor karena semakin lama pengeringan maka nilai inherent moisture akan turun dan nilai kalor akan naik.
Pelatihan Teknik Hidroponik untuk Mengatasi Lahan Berkadar Garam Tinggi pada Masyarakat Pesisir Gampong, Kuala Langsa, Aceh
Authors: Amri Yulida , Mardina Vivi , Harmawan Tisna
Published: December 2020

Gampong Kuala Langsa merupakan salah satu desa yang terletak di pesisir Kecamatan Langsa Barat, Langsa, Aceh. Secara geografis, Gampong terletak di dataran rendah sehingga menyebabkan terjadinya pasang naik air laut. Akibatnya tanah di Gampong Kuala Langsa memiliki tingkat salinitas tinggi, yakni sekitar 28,3—36 ppm. Kondisi tanah tersebut sangat tidak menguntungkan untuk bercocok tanam sayuran. Selain keadaan tanah yang tidak menguntungkan, terbatasnya lahan yang tersedia (dialihfungsikan sebagai tambak dan hutan mangrove) menjadi permasalahan mitra dalam memenuhi kebutuhan sayuran secara mandiri. Solusi permasalahan tersebut adalah dengan melakukan pengenalan dan penerapan sistem bercocok tanam secara hidroponik karena sistem ini sangat cocok diterapkan di daerah dengan kondisi tanah yang memiliki salinitas tinggi dan lahan terbatas. Bentuk kegiatan pengabdian ini adalah pelatihan yang terdiri atas tiga tahapan utama, yaitu survei lokasi dan sosialisasi, pelatihan, dan pemonitoran/evaluasi. Berdasarkan hasil kegiatan dapat disimpulkan bahwa (a) pengetahuan masyarakat mengenai teknik hidroponik meningkat yang ditandai dengan respons positif; (b) bercocok tanam secara hidroponik menggunakan metode nutrient film technique (NFT) dan metode rakit apung (metode sederhana) berhasil dilaksanakan oleh ibu-ibu PKK; dan (c) kegiatan ini sangat bermanfaat bagi masyarakat Gampong Kuala Langsa, khususnya ibu-ibu PKK sebagai sarana pendidikan kemandirian pangan.
Comparing and Contrasting: Ophelia and Lady Macbeth
Authors: Haque Md. Ziaul , Sekhar Roy Prof. Dr. Himadri
Published: December 2020

Ophelia in “Hamlet” and Lady Macbeth in “Macbeth” have several comparisons and contrasts in their personalities. Both of them suffer from madness. However, Ophelia is submissive and Lady Macbeth is commanding. In this sense, they primarily appear like two opposed persons. But, they both display resemblances as they depend on men, and devoid of this dependence, they face devastations. The over-reliance of Ophelia on Polonius, Laertes, and Hamlet directs her into insanity once they are absent. Similarly, Lady Macbeth attacks the virility of Macbeth which leads to his rejection of her, triggering her eventual suicide.
MATHEMATICS EDUCATORS’ PERSPECTIVES ON CULTURAL RELEVANCE OF BASIC LEVEL MATHEMATICS IN NEPAL
Authors: Acharya Bed Raj , Kshetree Mukunda Prakash , Khanal Bishnu , Panthi Ram Krishna , Belbase Shashidhar
Published: December 2020

The main purpose of this paper was to explore mathematics educators’ perception of the cultural relevance of basic level mathematics in Nepal. The design of this study involved an interpretive qualitative approach by administering in-depth interviews with five purposively selected mathematics educators teaching at five higher education institutions in the Kathmandu valley. Each interview was audio-recorded and transcribed for coding and constructing themes. The major themes that emerged were teaching in a mother language, contextualized Ethnomathematics, and the local knowledge in the curriculum as a teaching approach. The findings of the study can be helpful to curriculum designers and teachers at the basic level of mathematics. The study also adds to the literature of cultural aspects of mathematics teaching and learning and curriculum design.
Densidad, módulos dinámicos longitudinales e índices de calidad resultantes del densificado de la madera de especies tropicales
Authors: Sotomayor Castellanos Javier Ramón , Adachi Koji , Iida Ryuichi , Hayashi Tomoyuki
Published: December 2020

El aumento en la magnitud de una característica física de la madera, sin depreciar otras propiedades, se considera un avance tecnológico con posibles aplicaciones en ingeniería. Así, bajo la hipótesis de que el densificado de la madera aumenta su densidad y su módulo dinámico, la investigación tuvo como objetivos, por una parte, determinar estos parámetros, para comparar el comportamiento de la madera sólida frente a la madera densificada, y por otra, calcular a posteriori, los índices de densificado, elástico y de calidad. Se densificaron veinte probetas de las siguientes especies: Cupressus lusitanica, Cedrela odorata, Swietenia macrophylla, Tabebuia donnell-smithii, Fraxinus uhdei, Fagus grandifolia subsp. mexicana, Dalbergia palo-escrito y Guazuma ulmifolia. Tanto antes como después del tratamiento se realizaron pruebas de vibraciones longitudinales. Como resultado del densificado, las densidades de las maderas aumentaron en promedio 35% y los módulos dinámicos se incrementaron 46%. Los resultados de los índices de densificado, elásticos y de calidad sugieren que el tratamiento de densificado es eficaz para aumentar la densidad y el módulo dinámico de maderas con un amplio rango de densidades.
La intensidad eléctrica y la biorremediación de Aspergillus niger en suelos contaminados con hexadecano, en Loreto, Perú
Authors: León Vargas Frank Romel , Bardales Grández Kosseth Marianella , García Pérez Víctor , Moreno Eustaquio Walter , Jara Herrera Cleto , Perdiz Dávila José Manuel
Published: December 2020

La conservación del medio ambiente es un tema de interés mundial para aminorar los efectos del cambio climático. Es así que la biorremediación es una técnica que se está desarrollano actualmente por su efectividad y bajo costos. En el presente estudio se determinó la electrobiodegradabilidad del hexadecano empleando Aspergillus niger inmovilizado. Se aisló el Aspergillus niger de un suelo contaminado con petróleo y se identificó por su morfología macroscópica y microscópica. El soporte fue un suelo estéril tipo franco-arenoso, el cual fue contaminado con 180 mg de hexadecano (HXD)/gramo de suelo. El cultivo de Aspergillus niger se reactivó en agar papa dextrosa y las esporas se cultivaron en agua destilada más Tween 80 e inmovilizaron en alginato de calcio. Los ensayos se realizaron a temperatura ambiente (30 ± 2°C), las intensidades de corriente eléctrica usadas fueron de 5 mA, 10 mA y 15 mA, durante un periodo de 12 días. El hexadecano residual se determinó por cromatografía de gases. Se concluye que la intensidad de corriente eléctrica óptima en el rendimiento de disminución de hexadecano por esporas de Aspergillus niger inmovilizado en alginato de calcio es 10 mA, con un valor de 14975,76 mg/kg por día. Se logró electrobiodegradar el 99,83% de hexadecano.