bluuebunny/crossref_metadata_2025 huggingface dataset:
Does Use of Ureteral Access Sheath Lower Postoperative Infection Rates After Flexible Ureteroscopic Stone Management ? – a Critical Evaluation
Authors: Asik Alper , Erdogan Erhan , Suceken Ferhat Yakup , Aydin Mehmet Erhan , Uslu Mehmet , Bicaklioglu Fatih , Sehinler Emre Burak , Sarica Kemal
Published: August 2024

Aim : To evaluate the possible impact of ureteral access sheath (UAS) usage on the infectious complications following flexible ureteroscopy (fURS)
Patients and methods :
A total of 93 cases with solitary kidney stones (<15 mm) underwent fURS. To evaluate the possible effect of UAS use on the infectious complications after the procedures, cases were divided into two groups based on the use of UAS as; Group 1 (n: 51) cases treated with UAS and Group 2 (n: 42) cases treated without UAS during fURS. Following the stone management, treatment parameters and follow-up data were evaluated regarding the success rates, complications with an emphasis on infective onesandthe need for urgent admission rates were comparatively evaluated in both groups.
Results:
While the mean age of the cases was 48,2 years, mean stone size was 11,89 mm. The mean surgery time was 56.03 ± 13.17 minutes and the overall stone free rate(SFR) was 88.2%. Mean age value, body mass index, and mean degree of hydronephrosis did not significantly differ in both groups. Similarly, mean stone size, stone number and stone density were similar in both groups (p=0.79, p=0.43, and p:0.99, respectively).Although the operative time was shorter in cases operated with UAS, as an advantage,infectivecomplications were found to be significantly higher in these cases (p=0.021). However, peroperative complications were found to be higher in cases operated without an access sheath during fURS.
Conclusions :
Our results clearly demonstrated that although the use of UAS may shorten the operative time as an advantage, this application may not have a meaningful effect on the incidence of infective complications after flexible ureteroscopic stone management.
Loss of fatty acid-binding protein 7 enhances metastasis in B16F10 melanoma cells through phenotypic shift
Authors: Wannakul Tunyanat , Miyazaki Hirofumi , Maekawa Motoko , Kagawa Yoshiteru , Yamamoto Yui , Owada Yuji
Published: August 2024

Melanoma possesses the characteristic phenotypic plasticity, enhancing its metastatic formation and drug resistance. Lipid and fatty acid metabolism are usually altered to support melanoma progression and can be targeted for therapeutic development. Fatty acid binding protein 7 (FABP7) is highly expressed in melanomas and is shown to support its proliferation, migration, and invasion, but the mechanisms remain unclear. Our study aimed to link FABP7 to lipid metabolism and phenotypic shift in melanomas. We established the Fabp7-knockout (KO) B16F10 melanoma cells, which showed an enhanced invasion through matrix-coated membrane, without significant change in proliferation. Similar outcomes were obtained when using RNA interference targeting FABP7. Fabp7-KO cells injected into mice exhibited slower primary tumor growth, but formed higher metastatic foci count in the lungs. We also discovered a higher saturation in overall lipids, phosphatidylcholines, and triacylglycerols. We observed transcriptional shifts toward the invasive MITFLow/AXLHigh phenotype, with upregulation of transforming growth factor-beta (TGF-β) receptor mRNAs. In conclusion, FABP7 may help balancing lipid saturation and maintain the proliferative state of melanomas, mitigating invasiveness and metastatic formation.
A fluorescent sensor for rapid and quantitative aquatic bacteria detection based on bacterial reactive oxygen species.
Authors: song tingshan , xiao ruilin , tian baohua , li xinxin , liang haixia
Published: August 2024

Determination of total number of bacteria is vital for water pollution monitoring. However, fast, portable and quantitative on-site aquatic bacteria detection remains challenging. Here, a fluorescence sensor for bacterial concentration detection based on Ag@carbon dots composites (Ag@CDs) were developed. Fluorescence of CDs was quenched by plasmon-enhanced resonance energy transfer from CDs to nano Ag and recovered due to interaction with bacteria. Ag@CDs with controllable fluorescence “OFF-ON” was prepared through regulation of Ag and CDs composition reaction. Ag+ concentration-dependent fluorescence quenching and bacterial concentration-dependent fluorescence recovery provided Ag@CDs the support for bacterial quantitative detection. After exposure to Ag@CDs, bacteria quickly produced ROS which remained unchanged at 5 min, that is the basis of rapid test of bacteria. Ag@CDs-based fluorescence sensing system was optimized and exhibited a wide linear range of 7×104~4×107 CFU/mL, low detection limit of 4×104 CFU/mL, short response time of 5 min and high selectivity. The 96-well plate assay for quantitative measurement and test strips assay for semi-quantitation were developed for rapid in-field aquatic bacteria detection. Therefore, this study could give a new sight for application of Ag@CDs for rapid on-site aquatic bacteria detection in water quality monitoring.
Measuring multidimensional inequality of opportunity
Authors: Kapera Marek , Kobus Martyna , Peragine Vito
Published: August 2024

This paper extends the measurement of inequality of opportunity (IOP) to the case in which individual outcomes are multidimensional (e.g. income, health). We adopt an axiomatic approach to the construction of IOP measures. We characterize two classes of social welfare functions, each endorsing ex ante compensation but different reward principles: (1) utilitarian and (2) inequality averse. For each class we develop implementable conditions analogous to Lorenz dominance and IOP measures. As a major result we ax-iomatically characterize a multidimensional inequality of opportunity index corresponding to the Tsui (1995) inequality index applied to the framework of equality of opportunity. The measure is sensitive to dependence between outcomes – a distinctive feature of multidimensional distributions, and has a straightforward interpretation. Using the 2019 wave of EU SILC data we show that the multidimensional analysis of inequality of opportunity in Europe reveals important differences with respect to the analysis based on income alone, showing the value of the multidimensional perspective.
JEL classification: D63, I32
Study on the Measurement of high-quality development Efficiency and Influencing Factors in the Yellow River Basin, China
Authors: Qin Jianhui , Zhang Fen , Zhu Jiahao , Wu Yuping
Published: August 2024

Pollution of the environment and a lack of resources and energy are the hallmarks of the Yellow River Basin. Therefore, maximizing resource allocation and fostering the Yellow River Basin’s high-quality development depend heavily on increasing high-quality development efficiency. However, it is unclear what factors affect the high-quality development efficiency in the Yellow River Basin and how spatially relevant they are. This study used the SUPER-EBM model and the Malmquist index model to measure the high-quality development efficiency, spatial correlation, and its affecting elements in the Yellow River Basin. The results show: (1) Overall, the efficiency of high-quality development in the Yellow River Basin shows an overall trend of low in the east and high in the west. Growth in high-quality development efficiency relies mainly on technological progress and less on the degree of technology utilization. (2) Overall, the spatial correlation of the high-quality development efficiency of cities in the Yellow River Basin has been weakening annually, and the high-quality development of cities has been diversified. The higher portions of the basin have a notable concentration of high-efficiency cities. In contrast, the middle and lower reaches of the confluence have a nearby distribution of high and low-efficiency cities. (3) Negative geographical spillovers of high-quality development efficiency between high-efficiency and low-efficiency regions. The overall high-quality development efficiency of cities in the Yellow River Basin is positively correlated with the level of economic advance, urbanization, factor endowment, financial support, and education support. However, they are negatively correlated with energy consumption, industry structure (the share of the second industry), the level of utilization of foreign capital, and environmental pollution.
Laboratory analysis of colour and texture-induced oviposition in green lacewing (Chrysoperla zastrowi sillemi)
Authors: Mahla Kapil , Kalkal Deepika , Yadav Sunita , Saini Ankit , Mehla Sumit , Saklani Kritika
Published: August 2024

This research is aimed at determining the colour and texture that Chrysoperla zastrowi sillemi prefers for egg-laying under controlled conditions. Results have shown that when a white muslin cloth is used, the preferred colours for laying eggs are white muslin cloth, brown and black paper while under black muslin cloth, the most preferred colours are black muslin cloth, brown and black paper. The analysis of textures showed that rough surfaces were significantly preferred; brown, black and violet papers had the highest number of eggs. The statistical analysis using t-tests and ANOVA (F-tests) revealed that there are significant differences between preferences on oviposition which indicates that both colour and texture play a combined influence on the egg-laying behaviour in these lacewings. This discovery could revolutionize rearing environments: it can be regarded as an implication for taking biological control strategies into account based on such findings.
Effects of particle size and substitution level of brewer’s spent grain on physicochemical, nutritional, and sensory properties of cookies
Authors: Putthasang Parichat , Payongsri Panwajee , Wipatanawin Angkana , Kapcum Chutikarn , Sriprab Jiratthitikan , Chansong Suwan , Suphantharika Manop
Published: August 2024

Brewer’s spent grain (BSG), a major by-product of beer production, is rich in nutrients, inexpensive, and annually produced in large quantities, but is currently underutilized. In this research, the influences of particle size, i.e. coarse, medium, and fine particle size with a d4,3 value of 756.67, 561.67, and 158.33 µm, respectively, and substitution level, i.e. 10, 20, and 30% dried and ground BSG powder for wheat flour, on the physicochemical, nutritional, and sensory properties of cookies were investigated. The water and oil holding capacity of BSG powder was higher than that of wheat flour and increased with increasing particle size. The protein, fiber, ash and total phenolic content as well as the antioxidant capacity of the BSG-enriched cookies were higher than those of the control cookies and increased with increasing substitution level. The addition of BSG led to a reduction in the hardness and spread ratio of cookies, the intensity of which increased with increasing substitution level (only for hardness) and particle size of BSG. The color parameters L* and b* values decreased, while the a* value increased with increasing substitution level and decreasing particle size of BSG. The sensory evaluation showed that the acceptable substitution level of BSG increased with the reduction of particle size from 20% for coarse BSG powder to 30% for medium and fine BSG powder. The appropriate particle size is therefore a medium particle size with a substitution level of up to 30%.
CrossTransFuse:A Method for Colorectal Polyp Segmentation Incorporating Multi-Scale Cross-Attention and GiFusion Mechanisms.
Authors: Xue Tao , Liu Wenwen , Lv Wen , Xi Long
Published: August 2024

Due to the varying sizes and shapes of colorectal polyps, along with their blurred textures and boundaries, segmenting the polyp boundary regions is challenging, thereby increasing the risk of misdiagnosis or missed diagnosis. This paper proposes a polyp segmentation method called CrossTransFuse, which effectively captures the subtle differences and complex features of polyps by designing a multi-scale interaction strategy. Additionally, the proposed GiFusion module integrates the interactive features of the Mask R-CNN and Transformer branches and connects them through residual blocks. The resulting interactive features can effectively capture both global and local contexts at the current spatial resolution,achieving finer polyp boundary segmentation and target localization. We test our model on five widely used polyp segmentation datasets, and the results show that, compared with advanced polyp segmentation networks, CrossTransFuse achieves more precise segmentation of polyp boundary regions on the datasets.
Implementation of whole-course high-quality nursing in percutaneous nephrolithotomy for the treatment of urinary calculi and its effects on complications
Authors: Yuan Binglei
Published: August 2024

Objective: This paper aimed to unravel the implementation of whole-course high-quality nursing in percutaneous nephrolithotomy (PCNL) for the treatment of urinary calculi and its effects on complications.
Methods: Ninety-five patients with urinary calculi were selected and all received PCNL. The patients were randomly separated into two groups, of which 50 cases were in the control group, received conventional nursing throughout the treatment, and 45 cases were in the observation group, accepted whole-course high-quality nursing on top of the control group. Postoperative recovery time, including bed time, pain relief time, and hospitalization time was compared. The psychological status was measured by Self-Rating Anxiety scale (SAS) and Self-Rating Depression Scale (SDS). The postoperative pain degree was tested by Visual Analogue Scale (VAS) at 6 h, 12 h, and 24 h postoperatively. Quality of life was assessed by the Generic Quality Of Life Inventory-74 (GQOLI-74). Nursing satisfaction, treatment efficacy, and complications were compared.
Results: The observation group possessed shorter bed time, pain relief time, and hospitalization time and reduced SAS and SDS scores after nursing versus the control group. VAS scores of patients in the observation group at 6 h, 12 h, and 24 h postoperatively were reduced versus those in the control group. The scores of all dimensions of GQOLI-74 in the observation group were raised relative to the control group. The observation group possessed higher nursing satisfaction and clinical efficacy and reduced complications than the control group.
Conclusion: During the treatment period of PCNL for urinary calculi, the implementation of whole-course high-quality nursing effectively reduces postoperative complications, regulates patients’ adverse psychological status, and has a positive effect on improving the quality of life, which has promotion value.
Racial Composition and Population Well-being Across U.S. Counties
Authors: Cheung Felix , Feng Karina , Lee Yeeun Archer , Chan Elizabeth , Chan Kenith
Published: August 2024

There are two opposing perspectives regarding the impact of racial composition in a community on well-being: the homophily hypothesis suggests advantages of living within a homogenous in-group, while the diversity hypothesis proposes benefits of living in racially diverse communities. We examined how changes in relative racial composition within U.S. counties are associated with the life satisfaction of Asian, Black, Hispanic, Indigenous, White individuals (n = 2,023,217). Results based on compositional data analyses reveal that neither homophily nor diversity hypothesis provides a one-size-fits-all explanation for how racial composition shapes well-being. For instance, increased densities of Blacks are associated with increased life satisfaction among Blacks (supporting homophily), while increased densities of non-Asians are linked to increased life satisfaction among Asians (supporting diversity). Neither of the two hypotheses was supported among Whites. These findings underscore the importance of recognizing the varied effects that racial composition has on the lives of different racial groups.
Optimizing Cloud Resource Allocation with Machine Learning: A Comprehensive Approach to Efficiency and Performance
Authors: Syed Sadia , Albalawi Eid Mohammad
Published: August 2024

Cloud computing has become a cornerstone of modern IT infrastructure, and effective resource management is essential for maximizing performance and minimizing costs. This paper explores the application of machine learning algorithms to optimize cloud resource management. We utilize datasets that capture key performance metrics such as CPU usage, memory consumption, and network traffic. Our methodology involves preprocessing and analysing these datasets to develop predictive and optimization models aimed at improving resource allocation and efficiency. We apply various machine learning techniques, including regression analysis, reinforcement learning, and clustering, to address challenges related to resource utilization and cost management. The results are visualized through performance metrics graphs, heatmaps, and comparison charts that illustrate the impact of our models on cloud resource optimization. Interactive dashboards are also employed to provide real-time insights into resource management improvements. This research highlights the intersection of AI and cloud computing, demonstrating how machine learning can significantly enhance the efficiency and effectiveness of cloud resource management.
Adsorptive and Catalytic Ti3C2S2 MXene for High‐Performance Lithium–Sulfur Batteries
Authors: Wang Qing-song , Weng Zhaoyin , Zhang Jinghui
Published: August 2024

MXenes have emerged as promising candidates for hosting sulfur in lithium-sulfur (Li-S) batteries due to their exceptional electrical conductivity. Despite recognition of the significant influence of functional groups on the MXene surface on sulfur conversion reactions, a clear experimental understanding remains elusive. This study unveils that Ti3C2 MXene functionalized with –S groups demonstrates superior capabilities in anchoring and catalyzing lithium polysulfides (LiPSs) compared to counterparts functionalized with –Cl and –F groups. The Ti3C2S2 MXene is synthesized via the molten salt method, followed by functional group replacement. Ti3C2S2 MXene exhibits robust chemisorption strength, effectively mitigating LiPS dissolution and shuttling. Additionally, it demonstrates remarkable electrocatalytic prowess for Li2S deposition/decomposition, thereby enhancing reaction kinetics. As a result, Ti3C2S2 MXene-modified separators allow Li-S cells to achieve a high capacity of 1305 mAh/g at 0.1 C, alongside excellent cyclic retention of ≈81% after 1000 cycles. Even with an S loading of 6.5 mg/cm2, it attains a notable areal capacity exceeding 5.5 mAh/cm2. This work underscores the potential of surface modification strategies in boosting the anchoring and electrocatalytic performance of Ti3C2S2 MXene in Li-S batteries.
Mengembangkan Kemampuan Kognitif Melalui Alat Permainan Edukatif Match Colors di TK Kartika Siliwangi
Authors: Ruhiyat Silvani , Widjayatri Rr. Deni
Published: August 2024

Upaya untuk meningkatkan pemahaman mengenai bentuk geometri dan warna pada anak usia 3-4 tahun di TK Kartika Siliwangi Kota Serang, Banten, dilakukan melalui penerapan Alat Permainan Edukatif (APE) Match Colors. Penelitian ini memiliki tujuan utama untuk mengembangkan permainan Match Colors dengan maksud meningkatkan perkembangan kognitif anak usia dini. Metode penelitian yang digunakan adalah metode pengembangan dengan pendekatan kualitatif. Pengumpulan data dilakukan melalui observasi, dokumentasi dan wawancara. Analisis data dilakukan dengan menggunakan sampel instrumen. Hasil analisis menunjukkan bahwa APE Match Colors terbukti cukup efektif dalam membantu meningkatkan perkembangan kognitif anak usia 3-4 tahun. Dengan demikian, penelitian ini menyimpulkan bahwa permainan Match Colors valid dan efektif sebagai alat untuk mengembangkan dan merangsang perkembangan kognitif anak usia dini.
Enhancing Bio-Fertilization Potential of Introduced Hedysarum Species Through Indirect Root Inoculation: Implications for Agro-Ecological Sustainability in Arid Lands
Authors: SEBIHI Abdelhafid , MOUSSAOUALI Bakir , HAMDI-AÏSSA Baelhadj , KADI Si Ammar , BOURAS Noureddine
Published: August 2024

Saharan soils are devoid of Rhizobium bacteria specific to the Sulla plants which is indispensable for nitrogen fixation and soil fertility. The present study aims to test the possibility of formation nodules on the roots of some species of Hedysarum (Sulla) genus introduced in Ghardaïa region with indirect inoculation in the reason to optimize the use of nitrogen fertilizers. Three soil samples were chosen from three different districts of Algeria (Tizi-Ouzou, Sétif and El-Tarf) to be used as substrate and source of bacterial strains for three different species of Sulla (Hedysarum coronarium, Hedysarum carnosum, Hedysarum flexuosum). The results showed the formation of a considerable number of nodules in all treatments. The effect of species and samples of soils on the studied parameter was highly significant (p<0.000) at the 5% significance level. All cultivated species in the soil of Sétif could form significant more nodules compared to other soils. The disparity in the average number of nodules formed in the soil of Sétif represents a rate of 78.75% compared to the soil of Tizi-Ouzou. This study could contribute to improve fodder production of Sulla species cultivated in Ghardaïa region and also provides a forage rich in protein for local livestock.
Experiments Validated the Development of Zebrafish Embryos and Toxicological Mechanism of Borneols in Perinatal Period
Authors: Xie Qian , Lu Danni , Ma Rong , Zeng Xuxin , Guo Jialiang
Published: August 2024

Background:

Studies have confirmed that high dose borneol has perinatal toxicity and has a certain
effect on embryonic development. However, there is little about the effect of borneol on the development of zebrafish
embryos. Therefore, we compared the effects of D-borneol, L-borneol and synthetic borneol on the
growth and development of zebrafish embryos, and predicted the possible mechanism of perinatal toxicity.

Methods:

The embryonic mortality rate, hatching rate, and heart rate of each group were recorded at 48 hpf to
compare the effects of borneols on the development of zebrafish embryos. Network pharmacology and molecular
docking technology were used to predict the possible mechanism of perinatal toxicity.

Results:

We found that borneols increased the mortality at 24 and 48 hpf, inhibited the autonomous movement
behavior at 24 hpf, and affected the hatching rate and heart rate at 48 hpf. Network pharmacology analysis
showed that borneols had the same toxic targets in the perinatal period and were involved in regulating perinatal
toxicity by regulating pathways in cancer, chemical carcinogenesis-receptor activation, PI3K-Akt and
others. Molecular docking showed that the binding activity of the active ingredients and the core target was at
a medium level, and the binding activity of the borneols active ingredients and the core target was not much
different.

Conclusion:

Three kinds of borneol on the development of zebrafish embryos were different. The toxicity of
L-borneol was the lowest. The mechanisms of perinatal toxicity were related to inflammation, apoptosis, cell
cycle and growth, differentiation and reproduction.
A Cross-sectional Comparative Analysis of Eleven Population Pharmacokinetic Models for Docetaxel in Chinese Breast Cancer Patients
Authors: Wang Genzhu , Sun Qiang , Li Xiaojing , Mei Shenghui , Li Shihui , Li Zhongdong
Published: August 2024

Objective:

Various population pharmacokinetic (PPK) models have been established to
help determine the appropriate dosage of docetaxel, however, no clear consensus on optimal dosing
has been achieved. The purpose of this study is to perform an external evaluation of published models
in order to test their predictive performance, and to find an appropriate PPK model for Chinese breast
cancer patients.

Methods:

A systematic literature search of docetaxel PPK models was performed using PubMed,
Web of Science, China National Knowledge Infrastructure, and WanFang databases. The predictive
performance of eleven identified models was evaluated using prediction-based and simulation-based
diagnostics on an independent dataset (112 docetaxel concentrations from 56 breast cancer patients).
The -2×log (likelihood) and Akaike information criterion were also calculated to evaluate model fit.

Results:

The median prediction error of eight of the eleven models was less than 10%. The model
fitting results showed that the three-compartment model of Bruno et al. had the best prediction performance
and that the three compartment model of Wang et al. had the best simulation effect. Furthermore,
although the covariates that significantly affect PK parameters were different between
them, seven models demonstrated that docetaxel PK parameters were influenced by liver function.

Conclusions:

Three compartment PPK models may be predictive of optimal docetaxel dosage for
Chinese breast cancer patients. However, for patients with impaired liver function, the choice of
which model to use to predict the blood concentration of docetaxel still requires great care.
Low-Calorie Sweeteners and Reproductive Health: Evidence and Debates
Authors: Celik Atalay Ece , Er Demirhan Buket , Sagdıcoglu Celep Adviye Gulcin
Published: August 2024

The reduction in sugar consumption has led to increased use of low-calorie artificial
sweeteners. This coincides with an increase in infertility rates, suggesting that low-calorie artificial
sweeteners may negatively affect reproductive health. Low-calorie sweeteners may affect
oxidative stress, glucose regulation, and the microbiota, which are associated with reproductive
health. Therefore, a review was conducted to examine the effects of commonly used low-calorie
sweeteners on reproductive health through potential biological mechanisms. This review addresses
the effects of low-calorie sweeteners in a wide range of areas, such as infertility, pregnancy and
neonatal health, and early menarche. Recent studies have indicated potential adverse effects of artificial
sweeteners on reproductive health. Research has examined the potential impacts of artificial
sweeteners on various parameters, such as hormone levels, sperm quality, sperm motility, ovarian
function, and pregnancy outcomes. However, the findings of current studies are inconsistent, and
these disparate results may stem from metabolic differences among different types of artificial
sweeteners, variations in research methodologies, diversity in sample sizes, and fluctuations in
study populations. Therefore, further research is needed to comprehensively understand the effects
of artificial sweeteners on reproductive health.
Sekolah Ramah Anak Dalam Teori Belajar Humanistik Perspektif Psikologi Pendidikan Islam
Authors: Sasmita Reni , Wantini Wantini
Published: August 2024

Akhir-akhir ini, anak-anak sering menjadi korban kekerasan di sekolah. Sekolah seharusnya menjadi lingkungan yang aman dan nyaman bagi anak sehingga potensi yang terdapat dalam diri anak dapat dikembangkan. Selain itu, guru yang menggunakan slogan sekolah ramah anak nyatanya belum mengimplementasikan sekolah ramah anak. Proses pembelajaran masih berpusat pada guru dengan gaya belajar, metode strategi, model yang sesuai dengan potensi siswa. Penelitian ini bertujuan untuk mendeskripsikan sekolah ramah anak dalam perspektif teori belajar humanistik. Penelitian ini menggunakan metode kualitatif dengan library research. Hasil dari penelitian ini adalah bahwa terdapat hubungan antara konsep sekolah ramah anak dengan teori belajar humanistik. Hal ini berdasarkan hasil dari kesamaan antara konsep sekolah ramah anak dengan teori belajar humanistik yang menitikberatkan pada pengembangan potensi siswa dan proses pembelajaran yang berpusat pada siswa. Kedua konsep ini sama-sama menitikberatkan pada memanusiakan manusia dengan menggunakan metode dan model pembelajaran yang ramah anak sehingga dapat mengoptimalkan potensi siswa.Kata kunci: sekolah ramah anak, teori belajar humanistik
Pembelajaran Sosiologi Abad 21: Urgensi Asesmen Autentik bagi Peserta Didik
Authors: Syahrin Alif Alfi
Published: August 2024

Penelitian ini bertujuan memberikan alternatif penilaian autentik pada mata pelajaran Sosiologi berbasis Kurikulum Merdeka Belajar. Saat ini mata pelajaran sosiologi diidentikan dengan mata pelajaran hafalan bagi peserta didik. Untuk itu perlu diterapkannya penilaian autentik. Pendekatan yang digunakan dalam tulisan ini adalah pendekatan kualitatif dengan metode studi kepustakaan. Hasil penelitian menunjukkan bahwa pembelajaran mata pelajaran Sosiologi bagi peserta didik dipahami sebagai pembelajaran mata pelajaran yang tidak hanya sekedar menekankan pemahaman mengenai konsep, namun juga keterampilan dalam kreativitas hingga kemampuan beradaptasi dalam menghadapi tantangan pendidikan abad 21. Berbagai macam penerapan penilaian autentik dalam bentuk penilaian kinerja, penilaian projek, penilaian produk, penilaian portofolio dan tes uraian memberikan gambaran bahwa setiap bentuk penilaian memiliki karakteristiknya masing-masing sehingga dapat dikolaborasikan dengan setiap materi dalam mata pelajaran sosiologi. Hal ini perlu dilakukan untuk mengasah keterampilan peserta didik berdasarkan keterampilan yang dibutuhkan pada abad 21.Kata kunci: Pembelajaran Sosiologi, Asesmen Auntentik,  Abad 21
Teacher’s perceptions of policy and implementation of inclusive education at state junior high school in east Belitung regency
Authors: Miranda Fryda , Dewanti Septinda Rima
Published: August 2024

This research aims to describe teachers' perceptions of the policy and implementation of inclusive education at Junior High Schools in East Belitung Regency. Teacher perceptions are divided into three aspects, namely cognitive, affective and conative. This research is a descriptive quantitative approach with a survey research type. The subjects in this research were Junior High School teachers in East Belitung Regency with a sample size of 190 people. Data collection techniques use questionnaires. The data analysis technique used is quantitative descriptive analysis. This research found that 27,9% of teachers at Junior High School in East Belitung Regency have a positive perception toward inclusive education policy and 27,73% of teachers at Junior High School in East Belitung Regency have a positive perception toward implementation of inclusive education. Keywords: inclusive education policy, implementation of inclusive education, perception
A Child Carrying a Large Deletion in the 10p.15.3-p12.31 Region
Authors: Maharani Nani , Utari Agustini , Sihombing Nydia Rena Benita , Winarni Tri Indah
Published: August 2024

Partial deletion of 10p is a rare disorder. Common features of this disorder include intellectual disability, developmental delay, dysmorphic features, hypoparathyroidism, deafness, and renal anomalies, but the phenotypes can vary between patients. We report an infant girl presented with global developmental delay, distinctive facial features with cleft lip, congenital exotropia, laryngomalacia, atrial septal defect, and sensorineural hearing loss. 46, XX, del (10p→ter) was observed on the G-banded analysis. A chromosomal microarray was performed to obtain more detail on the deletion size and gene involvement that might be related to the clinical phenotypes, medical problems, and management. The deletion involved the region of 10p15.3–p12.31, with an approximate size of 19.528739 Mb. The size of deletion could determine the variability in phenotypes, and microarray is necessary to comprehend the deletion size and gene involvement better.
Recognizing the Role of ChatGPT in Decision-Making and Recognition of Mental Health Disorders among Entrepreneurs
Authors: Abdelwahed Nadia A. Abdelmegeed
Published: August 2024

Nowadays, mental health disorders have become a significant concern for everyone. There are diverse reasons emanating from the workplace, business, and everyday environment. Therefore, there is a current need to use technology to detect and review their symptoms and causes. Accordingly, in this study, the researcher attempted to recognize ChatGPT’s role in decision-making and the recognition of mental health disorders among Egyptian entrepreneurs. The researcher used a quantitative approach in this study based its findings on 332 valid samples. The study's results through path analysis using Analysis of Moment Structures (AMOS) confirmed a positive effect of user perception of ChatGPT and trust in ChatGPT on the decision-making process and recognition of mental disorders. On the other hand, the study found a negative effect of the decision-making process in recognizing mental disorders. On the other hand, this study’s findings demonstrate that the decision-making process hurts recognizing mental health disorders. This study's results assist the development of policies to improve available digital services, such as ChatGPT or AI, to increase societal awareness. Moreover, by providing empirical evidence from Egyptian entrepreneurs in a developing country context, this study’s findings contribute to the existing psychology, digital technology, and management literature.
Examining the Light Heart Mobile Device App for Assessing Human Pulse Interval and Heart Rate Variability: Validation Study
Authors: Klassen Stephen A , Jabbar Jesica , Osborne Jenna , Iannarelli Nathaniel J , Kirby Emerson S , O'Leary Deborah D , Locke Sean
Published: August 2024

Background

Pulse interval is a biomarker of psychological and physiological health. Pulse interval can now be assessed using mobile phone apps, which expands researchers’ ability to assess pulse interval in the real world. Prior to implementation, measurement accuracy should be established.

Objective

This investigation evaluated the validity of the Light Heart mobile app to measure pulse interval and pulse rate variability in healthy young adults.

Methods

Validity was assessed by comparing the pulse interval and SD of normal pulse intervals obtained by Light Heart to the gold standard, electrocardiogram (ECG), in 14 young healthy individuals (mean age 24, SD 5 years; n=9, 64% female) in a seated posture.

Results

Mean pulse interval (Light Heart: 859, SD 113 ms; ECG: 857, SD 112 ms) demonstrated a strong positive linear correlation (r=0.99; P<.001) and strong agreement (intraclass correlation coefficient=1.00, 95% CI 0.99-1.00) between techniques. The Bland-Altman plot demonstrated good agreement for the mean pulse interval measured with Light Heart and ECG with evidence of fixed bias (–1.56, SD 1.86; 95% CI –5.2 to 2.1 ms), suggesting that Light Heart overestimates pulse interval by a small margin. When Bland-Altman plots were constructed for each participant’s beat-by-beat pulse interval data, all participants demonstrated strong agreement between Light Heart and ECG with no evidence of fixed bias between measures. Heart rate variability, assessed by SD of normal pulse intervals, demonstrated strong agreement between techniques (Light Heart: mean 73, SD 23 ms; ECG: mean 73, SD 22 ms; r=0.99; P<.001; intraclass correlation coefficient=0.99, 95% CI 0.97-1.00).

Conclusions

This study provides evidence to suggest that the Light Heart mobile app provides valid measures of pulse interval and heart rate variability in healthy young adults.
Virtual Reality for the Treatment of Perinatal Mental health: A Rapid Scoping Review (Preprint)
Authors: Zorzi Chantal , Jean Jennifer , Côté Sylvana , St-André Martin , MacKinnon Anna
Published: August 2024

BACKGROUND

Mental health struggles are notably prevalent during the perinatal period, with studies highlighting increased rates of mood disorders among new parents, particularly since the COVID-19 pandemic. eHealth treatments have been growing in popularity, with research exploring innovative solutions such as virtual reality (VR), which offers a promising alternative or adjunct to established treatments through immersive technology.

OBJECTIVE

This rapid scoping review aims to evaluate the available VR applications for treating perinatal mental health disorders, focusing on their effectiveness in reducing symptoms such as anxiety and depression, which are common during the perinatal period.

METHODS

Adhering to the Joanna Briggs Institute guidelines and PRISMA-ScR, as well as making adjustments based on the Cochrane Rapid Reviews guidelines, a comprehensive search across five databases was conducted to identify relevant studies. Inclusion criteria consisted of studies utilizing VR interventions during the perinatal period with outcomes related to mental health symptoms. A total of 308 studies were screened, with 10 meeting the inclusion criteria for detailed analysis.

RESULTS

The review included studies primarily conducted in high-income countries from 2019 to 2024. The majority (80%) were randomized controlled trials, employing VR through head-mounted displays. Studies predominantly targeted anxiety and depression, with VR environments ranging from nature scenes to therapeutic content. Results suggest a positive impact of VR interventions on reducing anxiety and depression levels among participants.

CONCLUSIONS

VR appears to be a promising option for managing perinatal mental health. The immersive nature of VR may provide opportunities for emotional relief and support during this critical period through immersive and engaging experiences which can reduce symptoms of anxiety and depression. However, the body of research remains limited, indicating a need for further studies to explore the long-term benefits and potential integration of VR into perinatal healthcare practices. The promising results from initial studies encourage continued exploration and development within this innovative therapeutic field.
Illuminating IT Landscapes: A Comparative Analysis of Discovery in ServiceNow and BMC Helix
Authors: Yadav Sunil Kumar
Published: August 2024

Abstract: This research paper presents a comprehensive comparison of the Discovery applications offered by ServiceNow and BMC Helix. The study examines key features, discovery mechanisms, data collection capabilities, integration with CMDB, automation features, and analytics tools of both solutions. By evaluating their strengths and weaknesses in discovering and mapping IT assets and relationships, this paper aims to provide insights for organizations seeking to enhance their visibility into complex IT environments and improve overall IT service management.
Fibrodysplasia Ossificans Progressiva
Authors: Sethi Vivaan
Published: August 2024

Abstract: Fibrodysplasia Ossificans Progressiva (FOP), commonly known as Stoneman Syndrome, is an ultra-rare genetic disorder characterized by the progressive ossification of soft tissues, leading to the formation of a secondary skeleton. This paper provides a comprehensive analysis of FOP, examining its epidemiology, pathophysiology, clinical manifestations, diagnostic criteria, and current treatment approaches. Through a review of the latest research and case studies, this paper also explores the psychological and social impact of the disease, the challenges faced by patients, and the future directions for potential therapies. With fewer than 1,000 confirmed cases worldwide, FOP remains one of the most enigmatic and debilitating conditions in modern medicine.
Team personality characteristics and performance in a simulated largeaircraft instrument control task
Authors: Hui Duoduo , Cheng Shan , Liu Ke , Cong Lin , Zhang TaiHui , Huang MeiQing , Ma Jin , Teng ChaoLin , Hu Wendong
Published: August 2024

We investigated the relationship between personality characteristics and performance on a simulated large-aircraft instrument control task. The sample comprised 155 undergraduates in China, who completed the Cattell Sixteen Personality Factor Questionnaire to assess personality characteristics,
and were randomly allocated to one of 31 teams of five people. We used multiple regression analysis to establish a predictive model of team performance based on team personality elevation and team personality diversity integration models. The results showed that when the team personality elevation
integration was used as the independent variable, an increase in rule consciousness led to improvement in team performance, whereas an increase in vigilance, dominance, and social boldness led to a deterioration in team performance. When team personality diversity integration was used as the
independent variable, an increase in warmth and openness to change led to improvement in team performance, and an increase in sensitivity led to deterioration in team performance. The simulation task designed in this study provides a specific tool for research involving flight crews on large
aircraft. The findings provide a theoretical reference for optimum allocation of flight crews.
The impact of internet addiction on college students' academic procrastination: A moderated mediation model
Authors: Liu Min , Sun Wei , Chen Haonan , Fan Jianpeng
Published: August 2024

We examined the influence of internet addiction on academic procrastination among college students, with self-control and learning engagement as mediators and social comparison tendency as a moderator. Using data from 328 questionnaires completed by college students, this study revealed
that internet addiction was positively related to academic procrastination, and self-control and learning engagement had mediating effects on this relationship. Further, social comparison tendency played a moderating role, such that the effect of internet addiction on academic procrastination
was stronger when college students' social comparison tendency was low (vs. high). Implications of the findings are discussed.
Open to innovation: How a logo frame shapes consumer perception of the brand
Authors: Park Hyeyeon , Chen Yuting , Han Youngjee
Published: August 2024

We explored the influence on consumer behavior of a logo frame—a common design feature of logos. We proposed that whether a logo frame was present or absent would affect consumers' perception of brand innovativeness, thereby influencing their purchase intention. Through two studies
utilizing diverse logo types and brands, we demonstrated that frameless logos conveyed a sense of openness that enhanced consumers' perception of brand innovativeness, leading to a positive impact on their purchase intention. Our findings underscore the generalizability and practical significance
of logo-frame effects across different contexts, contributing to a deeper understanding of brand perception. Marketers can strategically leverage these insights to utilize visual-design elements that shape consumer perceptions and drive favorable responses toward a brand.
Formulation and evaluation of bioadhesive buccal Films of Domperidone co-crystals by using Tamarind kernel powder as mucoadhesive polymer
Authors: Rongali Sailaja , Panda Jagadeesh , Bankuru Kala Jyotsna , Badri Hanumanth , Bonela Manju Priya , Gonthupalli Bhavya
Published: August 2024

As solubility plays key role in drug dissolution and bioavailability lots of techniques to enhance solubility are evolved. One of the techniques is co crystallization. The main aim of the work is to enhance the solubility of domperidone by co crystallization using coformers like Para amino benzoic acid and succinic acid. The cocrystals were evaluated for melting point and solubility enhancement.  these cocrystals were used to prepare buccal films by solvent casting method. In the preparation of buccal films Tamarind kernel powder obtained from the seeds of Tamarind is used as mucoadhesive polymer and Hydroxy propyl methyl cellulose as film former, Polyethylene glycol 6000 as plasticizer, dehydrated banana powder as super disintegrant, sodium saccharin as sweetener and mixture of ethanol and water as solvents. The mucoadhesive strength of Tamarind kernel powder was determined using modified physical balance method. Four buccal films were prepared in which PDBF1 and PDBF2 are the two buccal films prepared using cocrystals of domperidone and Para amino benzoic acid and other two buccal films SDBF1 and SDBF2 with cocrystals of domperidone and Succinic acid. The buccal films were evaluated for different tests like folding endurance, swelling index and Surface pH. In vitro diffusion studies were conducted by Franz diffusion cell using egg membrane as semipermeable membrane and phosphate buffer of pH 7.4. The buccal films prepared with cocrystals of domperidone and succinic acid at weight ratio 1:2 has shown 86%drug release. The work has concluded that there is fold increase in aqueous solubility of Domperidone and the optimized formula is SDBF2 and Tamarind kernel powder can be used as mucoadhesive polymer in novel drug delivery systems.
Keywords: co crystals, solvent evaporation, muco adhesive, buccal films, solvent evaporation
Clinical and Haematological Study of Hijama-Bi’l-Shart (Wet Cupping) In the Management of Pain
Authors: Siddiqui Saif Ali , Shoaib Mohammad , Sultana Asia , Anas Mohammad , Khan Rizwan Hasan
Published: August 2024

Background: This randomized clinical and haematological study evaluated the effect of Hijama-Bil-Shart (Wet Cupping) on musculoskeletal pain and inflammatory markers in venous and cupped blood.
Materials and Methods: 110 patients with musculoskeletal pain were screened, with 90 diagnosed and included. After 30 subjects were lost to follow-up, 60 completed the study. Participants received 4 weekly sessions of wet cupping therapy over 4 weeks. Pain intensity was measured using VAS and KOOS scores, and inflammatory markers (Serum uric acid & CRP) were assessed in venous and cupped blood.
Results: Pain relief, measured by VAS, showed significant improvement across various musculoskeletal conditions: cervical spondylosis, frozen shoulder, low backache, sciatic pain, knee osteoarthritis, gout, and rheumatoid arthritis. KOOS scores for knee osteoarthritis improved significantly. Serum uric acid levels in venous blood were suggestively insignificant, while CRP levels decreased gradually but were not statistically significant. No adverse effects were reported.
Conclusion: Hijama-Bil-Shart (wet cupping) therapy is effective in relieving musculoskeletal pain and improving quality of life. It shows long-term benefits with sustained pain relief and gradual reduction in CRP levels. However, it is not effective in significantly reducing raised serum uric acid levels.
Keywords: Musculoskeletal pain, Wet cupping, VAS, KOOS, Hijama-Bil-Shart, CRP