bluuebunny/crossref_metadata_2025 huggingface dataset:
Anti-inflammatory effects of gallic acid in human gestational tissues in vitro
Authors: Nguyen-Ngo Caitlyn , Salomon Carlos , Lai Andrew , Willcox Jane C , Lappas Martha
Published: July 2020

Spontaneous preterm birth is the leading cause of neonatal mortality and morbidity globally. Activation of the maternal immune system leads to a downstream cascade of proinflammatory events that culminate in the activation of spontaneous uterine contractions and the rupture of the foetal membranes. Anti-inflammatory agents may be a novel therapeutic approach to prevent inflammation-induced myometrial contractions and premature rupture of foetal membranes. The polyphenol gallic acid has been previously shown to exert potent anti-inflammatory effects. Thus, this study aimed to determine the effect of gallic acid on proinflammatory and pro-labour mediators in cytokine-stimulated gestational tissues in vitro. In primary human cells isolated from myometrium and foetal membranes (decidua, and amnion mesenchymal and epithelial cells), gallic acid treatment suppressed inflammation-induced expression of proinflammatory cytokines and chemokines and extracellular matrix-degrading and matrix-remodelling enzymes. Gallic acid also significantly inhibited inflammation-induced myometrial activation as evidenced by decreased expression of contraction-associated proteins, the uterotonic PGF2α and collagen cell contractility. Using a global proteomic approach, gallic acid may differentially regulate proteins associated with collagen synthesis, cell contractility and protein synthesis in primary myometrial and decidual cells. In summary, gallic acid inhibited inflammation-induced mediators involved in active labour in primary cells isolated from myometrium and foetal membranes. These in vitro studies suggest that the polyphenol gallic acid may be able to suppress the production of proinflammatory and pro-labour mediators involved in myometrial contractions and rupture of foetal membranes. Future preclinical studies may elucidate the efficacy of gallic acid in preventing inflammation-driven preterm birth.
Implementation of a GSM base station and reception of LTE signals, applying radio defined by software
Authors: Chica-Pedraza Gustavo Alonso , Díaz-Sánchez Ángel Felipe , Espinosa-Buitrago Mónica , Angulo-Esguerra David Norberto
Published: July 2020

Santo Tomás University does not currently have the entire telecommunications infrastructure that allows its students to perform laboratory practices in the area of mobile telephony. Therefore, this research work has the purpose of implementing a mobile cellular telephone base (TMC), GSM 2G and the development of a LTE 4G signal reception system, all this through the use of software-defined radio and free software tools. The implementation of the base station generates and manages the wireless resource issued by it, in order to provide short text messaging services and voice call. On the other hand, the LTE 4G signal reception system was developed in the GNURadio software, which allows replicating a didactic and educational form of the whole process of generation and reception of basic mobile telecommunications services.
Reconstruction of the Largest Pedigree Network for Pear Cultivars and Evaluation of the Genetic Diversity of the USDA-ARS NationalPyrusCollection
Authors: Montanari Sara , Postman Joseph , Bassil Nahla V , Neale David B
Published: July 2020

The USDA-ARS National Clonal Germplasm Repository (NCGR) in Corvallis, Oregon, maintains one of the world’s largest and most diverse living Pyrus collection. A thorough genetic characterization of this germplasm will provide relevant information to optimize the conservation strategy of pear biodiversity, support the use of this germplasm in breeding, and increase our knowledge of Pyrus taxonomy, evolution, and domestication. In the last two decades simple sequence repeat (SSR) markers have been used at the NCGR for cultivar identification and small population structure analysis. However, the recent development of the Applied Biosystems Axiom Pear 70K Genotyping Array has allowed high-density single nucleotide polymorphism (SNP)-based genotyping of almost the entire collection. In this study, we have analyzed this rich dataset to discover new synonyms and mutants, identify putative labeling errors in the collection, reconstruct the largest pear cultivar pedigree and further elucidate the genetic diversity of Pyrus.
Increased Numeracy Skills of Children with Snakes and Ladders Game
Authors: Fidrayani Fidrayani , Syafrida Rina , Melodyana Puspa Ayu
Published: July 2020

This research aims to improve the ability to count 4 - 5 years old children with snakes and ladders in group A PAUD Dahlia. The method used in this research is collaborative classroom action research using Kemmis and Mc Taggart's models. CAR is implemented as an effort to overcome problems that arise in the classroom. Method is carried out in four stages, are planning, action, implementation, and reflection. The subjects of the study were students of group A PAUD Dahlia, ten (n=10) children. The object of this study is the ability to count 4 - 5 years old children. Data collection method used is observation. Technical data analysis was done in a descriptive qualitative and quantitative manner. The established success indicator is that at least 75% of 10 children reach the counting ability. This research was conducted in two cycles. The results of the study indicate that the numeracy skill has increased. Increased numeracy skills can be seen from the indicator ability to count objects 1-10, recognize the concept of numbers, recognize symbols 1-10, mention symbols 1-10, matching numbers with symbol numbers. Increased numeracy skills of children aged 4-5 years with snakes and ladders in the implementation of pre-action 31, 5%, and in the first cycle increased to 51.5%, because it is still less than the success criteria that should be carried out then the next action is cycle II and increased greatly good by getting a percentage of 85%. Many games for children was suggested for increase numeracy skills.
Stories and Storytelling for Moral Education: Kindergarten Teachers’ Best Practices
Authors: Rahiem Maila D.H. , Abdullah Nur Surayyah Madhubala , Rahim Husni
Published: July 2020

Habituation is the most common used form of moral education in early childhood education in Indonesia. However, this method has been found to be insufficient in contributing fully to young children’s moral development. An alternative method currently being promoted is the narrative method which involves the use of stories and storytelling. These two techniques provide children with justification to do good deeds and allow them to be critical of their actions. This research examined the best practices of teachers in the use of narrative method for the Moral Education of young children. Best practices show how we can use them to improve the teaching of Moral Education among young children and can serve as useful alternative to habituation. The findings revealed that there are five ways in which the kindergarten use stories and storytelling in teaching and learning moral education for young children, namely: to repeat the story; to include clear example; to explain the story; to dramatize the story; and to modify the story.
Cardiorespiratory and Pulse Oximetry Monitoring in Hospitalized Children: A Delphi Process
Authors: Schondelmeyer Amanda C. , Dewan Maya L. , Brady Patrick W. , Timmons Kristen M. , Cable Rhonda , Britto Maria T. , Bonafide Christopher P.
Published: July 2020

OBJECTIVES:

Cardiorespiratory and pulse oximetry monitoring in children who are hospitalized should balance benefits of detecting deterioration with potential harms of alarm fatigue. We developed recommendations for monitoring outside the ICU on the basis of available evidence and expert opinion.

METHODS:

We conducted a comprehensive literature search for studies addressing the utility of cardiorespiratory and pulse oximetry monitoring in common pediatric conditions and drafted candidate monitoring recommendations based on our findings. We convened a panel of nominees from national professional organizations with diverse expertise: nursing, medicine, respiratory therapy, biomedical engineering, and family advocacy. Using the RAND/University of California, Los Angeles Appropriateness Method, panelists rated recommendations for appropriateness and necessity in 3 sequential rating sessions and a moderated meeting.

RESULTS:

The panel evaluated 56 recommendations for intermittent and continuous monitoring for children hospitalized outside the ICU with 7 common conditions (eg, asthma, croup) and/or receiving common therapies (eg, supplemental oxygen, intravenous opioids). The panel reached agreement on the appropriateness of monitoring recommendations for 55 of 56 indications and on necessity of monitoring for 52. For mild or moderate asthma, croup, pneumonia, and bronchiolitis, the panel recommended intermittent vital sign or oximetry measurement only. The panel recommended continuous monitoring for severe disease in each respiratory condition as well as for a new or increased dose of intravenous opiate or benzodiazepine.

CONCLUSIONS:

Expert panel members agreed that intermittent vital sign assessment, rather than continuous monitoring, is appropriate management for a set of specific conditions of mild or moderate severity that require hospitalization.
Early Experience of COVID-19 in a US Children's Hospital
Authors: Kainth Mundeep K. , Goenka Pratichi K. , Williamson Kristy A. , Fishbein Joanna S. , Subramony Anupama , Barone Stephen , Belfer Joshua A. , Feld Lance M. , Krief William I. , Palumbo Nancy , Rajan Sujatha , Rocker Joshua , Scotto Tiffany , Sharma Smiriti , Sokoloff William C. , Schleien Charles , Rubin Lorry G. ,   NORTHWELL HEALTH COVID-19 RESEARCH CONSORTIUM
Published: July 2020

OBJECTIVES:

We aim to describe the demographics, clinical presentation, hospital course, and severity of pediatric inpatients with coronavirus disease 2019 (COVID-19), with an emphasis on healthy, immunocompromised, and chronically ill children.

METHODS:

We conducted a single-center retrospective cohort study of hospitalized children aged younger than 22 years with COVID-19 infection at Steven and Alexandra Cohen Children’s Medical Center at Northwell Health. Cases were identified from patients with fever and/or respiratory symptoms who underwent a nucleic acid amplification–based test for severe acute respiratory syndrome coronavirus 2.

RESULTS:

Sixty-five patients were identified. The median age was 10.3 years (interquartile range, 1.4 months to 16.3 years), with 48% of patients older than 12 years and 29% of patients younger than 60 days of age. Fever was present in 86% of patients, lower respiratory symptoms or signs in 60%, and gastrointestinal symptoms in 62%. Thirty-five percent of patients required ICU care. The white blood cell count was elevated in severe disease (P = .0027), as was the C-reactive protein level (P = .0192), compared with mild and moderate disease. Respiratory support was required in 34% of patients. Severity was lowest in infants younger than 60 days of age and highest in chronically ill children; 79% of immunocompromised children had mild disease. One death was reported.

CONCLUSIONS:

Among children who are hospitalized for COVID-19, most are younger than 60 days or older than 12 years of age. Children may have severe infection requiring intensive care support. The clinical course of immunocompromised patients was not more severe than that of other children. Elevated white blood cell count and C-reactive protein level are associated with greater illness severity.
Intersectoral component of the structural and functional management model: a methodology for developing regional prevention programs and evaluating its effectiveness (for example, the child population of certain administrative regions of Ukraine)
Authors: Demikhov Oleksii
Published: July 2020

Modern ideas about comprehensive assessments of the level of health are based on synthetic (complex, integral, multidimensional) indicators, the requirement for which is the need to take into account various (by origin and methods of obtaining) health indicators both at the individual and population, regional levels. In recent years, many methodological methods have been processed to obtain a comprehensive qualitative and quantitative assessment of the state of individual health. Obtaining a generalized qualitative and quantitative assessment remains the most important methodological task of modern theory and practice of public administration and public health. The purpose of the study was to develop a methodology for substantiating intersectoral regional prevention programs and an algorithm for evaluating their effectiveness using the example of a dysplastic-dependent pathology of the bronchopulmonary system in children. In developing and justifying population-based management models for early diagnosis and primary prevention, we used systematic population modeling methods. The expected indicators of the pathogenic and sanogenic effects of the most significant regional and environmental factors of the dysplastic-dependent pathology of the bronchopulmonary system among children are determined. Substantiated models of end results for modification of risk factors and the expected effectiveness of the N-factor regional and environmental program for the primary prevention of dysplastic dependent pathology of the bronchopulmonary system in children. Priority areas for the implementation of regional-population programs for the prevention of dysplastic-dependent pathology of the bronchopulmonary system in children due to the impact on controlled environmental environmental factors are determined. An example of calculating the expected effectiveness of children's health management through interdepartmental interaction at the regional level is given. Prospects for further research on this issue related to a prospective evaluation of the effectiveness of intersectoral programs to reduce the influence of regional environmental factors on the health status of the child population, in particular, dysplastic-dependent pathology of the bronchopulmonary system.
Transformation technologies in the processes of capable territorial communities developing
Authors: Molokanova Valentyna , Olkhovikova Julia
Published: July 2020

The article discusses issues related to the implementation of modern transformational development technologies in the field of reforming local self-government through the formation of capable united territorial communities. The article claims that today in Ukraine the first evolutionary stage of voluntary community unification has already been passed and now Ukraine is moving on to the next stage - community unification by the principle of ability. This second stage of decentralization involves a radical reduction in the number of districts through the unification and creation of new capable administrative and territorial units at the subregional level. This necessitates a change in the functions of local governments from the implementation of the existing external strategy, to structures that independently develop strategies and tactics, and are responsible for their decisions to the residents of the communities. The role and specific features of capable united territorial communities, as public law units that have all the necessary resources to solve local issues provided for by law, are described. It is proved that strategic goals require a systematic, step-by-step technology for the development and implementation of both strategic and tactical levels. However, among specialists from local economic development, certain gaps in understanding how to turn strategies into tactical development plans through projects and programs have been identified. Although project management has all the necessary tools to create mechanisms for implementing the developed strategy. It is the lack of knowledge on the practical application of well-known project management tools, which causes failures in the implementation of strategies. The article notes that the failure in the developed strategy implementation can be due to both shortcomings in the development of the strategy itself and errors in the development of tactical measures for its implementation. Highlighted shortcomings in the training of project competencies of persons related to the development of program-targeted documents in the newly united territorial communities. The development of transformational tools for united territorial communities through the integration of strategic planning and tactical project management is proposed.
Sociological and ethnopolitical aspects of state ethnic policy
Authors: Bondarenko Victor
Published: July 2020

The article presents the sociological and ethnological features (aspects) in the analysis of state ethnic politics. The possibilities of synthesis between sociological and ethnological methods in the process of analysis of state ethnic politics are determined. The relevance of the influence of sociological and ethnological aspects on the process of rational and prudent ethnic politics in the country in our time is analyzed. The definitions of sociology and ethnology and the sphere of their knowledge and scientific efficiency are given. Constructive derivatives during the synthesis of sociological and ethnological methods of cognition of society are found out. The work of foreign and Ukrainian scientists and researchers on state ethnic politics is considered. The historical process of the late nineteenth - twentieth centuries, which led humanity to the emergence of modern state-administrative issues and problems, is analyzed. The types of social structuring of societies and the social structure of modern Ukrainian society, which is considered to be the most acceptable and generally recognized, are defined as schemes. The ethnic structure of human society on the theory of ethnogenesis, proposed by LM Gumilev at the end of the twentieth century, and the author's vision of socio-ethnic structuring of societies in a schematic form are highlighted. The author presents a schematic view of one of the possible variants of the scientific vision of the ethno-social structuring of the societies of the world, including Ukrainian society. The logical definition of the important scientific term "nation" (nation) and the importance of universalizing the terminological and conceptual base in the analysis of national ethnic politics are presented. Conclusions have been made regarding the prospects for further development of public administration science.
The concept of «warrant» of the christian belief in Alvin Plantinga`S theistic philosophy
Authors: Filatova Mariia
Published: July 2020

The study focuses on the concept of warranted Christian belief, which was introduced by A. Plantinga. The purpose of the research is to consider the warrant as a property of the Christian belief, moreover through which it can become knowledge. The study scrutinizes the possibility of accepting faith without theistic arguments. The author analyzes A. Plantinga's classification of a warrant, for example, deontologism, coherentism and reliabilism. The author gives a general characteristic of warranted belief, moreover, the study stresses that belief has a warrant for a person if it is produced by cognitive faculties functioning properly, if a belief is formed in an appropriate epistemic environment, if cognitive faculties are operating according to a design plan reliably aimed at truth, if a person has no defeaters for that belief. The article emphasizes that if A. Plantinga's A/C model is true, then theistic belief is truly warranted, consequently a warrant of theistic belief depends on the proof of the existence of God. The author of the research contends that beliefs can have different degrees of the warrant, and if this degree becomes sufficient, belief becomes knowledge. Moreover, the author points out that one of the basic beliefs admitted by A. Plantinga is belief in God. The study analyzes four types of human interaction with God: internal instigation of the Holy Spirit, perception of God (sensus divinitatis), Holy Scripture, and faith. The main function of the internal instigation of the Holy Spirit is to inspire a human to have faith in God. Moreover, the author emphasizes that Christian beliefs, acquired by the internal instigation of the Holy Spirit, are not only warranted but have sufficient justification to be knowledge. The complex action of the perception of God and internal instigation of the Holy Spirit provide reliable, properly basic beliefs that are referred to the truth written in the Holy Gospel. As a result, the author comes to the conclusion that there are no convincing arguments for the Christian belief for those who have not accepted it. In the conclusion, the author points out that forming an A/C model, A. Plantinga creates a double problem, on the one hand, his goal is to warrant the truth of the theistic belief, and he performs his task, but, on the other hand, he tries to demonstrate warrant of the Christian belief, and presents the same opportunity to representatives of other theistic religions. Thus, instead of arguing with atheism, A. Plantinga turns to a discussion with non-Christian theistic religions.
Shear Damage Mechanism and Early Warning Study of Shale Standard Layer Casing
Authors: Wang Suling , Wang Xuefei , Chen Minzhan , Xie Wenqi , Zhang Ziheng , Yang Lei
Published: July 2020

Aiming at the problem of shear-induced casing damage caused by standard layer shale soaking water, the theory of rock mechanics is used to establish the fluid-solid coupling calculation model of the formation-cement ring-casing of the standard interval shale interbed, obtaining the strain and deformation changes of casing shear damage, and puts forward the casing logarithmic strain exacerbated area should prompt adoption of reasonable measures to slow down the casing damage. Three-level orthogonal numerical simulation experiments were carried out for the five factors affecting casing damage, the simulation results show the critical strain data of the casing damage and the true strain data of the casing under the influence of five factors. According to the statistical principle, the predictive mathematical model of the critical strain and true strain prediction of the casing is obtained by the multiple regression method, realize the prediction of the strain state of the casing under actual working conditions is realized, and then realize casing damage early warning.
Influence of Powder-to-Gel Ratio on Physicochemical Properties of a Calcium Silicate Sealer
Authors: Torres Fernanda F. E. , Perinoto Patricia , Bosso-Martelo Roberta , Chávez-Andrade Gisselle M. , Guerreiro-Tanomaru Juliane M. , Tanomaru-Filho Mario
Published: July 2020

Differences in liquid-to-powder ratio can affect the properties of calcium silicate-based materials. This study assessed the influence of powder-to-gel ratio on physicochemical properties of NeoMTA Plus. Setting time (minutes), flow (mm and mm²), pH (at different periods), radiopacity (mm Al) and solubility (% mass loss) were evaluated using the consistencies for root repair material (NMTAP-RP; 3 scoops of powder to 2 drops of gel) and root canal sealer (NMTAP-SE; 3 scoops of powder to 3 drops of gel), in comparison to Biodentine cement (BIO) and TotalFill BC sealer (TFBC). Statistical analysis was performed using one-way ANOVA and Tukey tests (α=0.05). BIO had the shortest setting time, followed by NMTAP-RP and NMTAP-SE. TFBC showed the highest setting time and radiopacity. BIO, NMTAP-RP, and NMTAP-SE had similar radiopacity. All materials promoted an alkaline pH. NMTAP-RP/SE presented lower solubility than BIO and TFBC. Regarding the flow, TFBC had the highest values, followed by NMTAP-SE, and NMTAP-RP. BIO had the lowest flow. In conclusion, NMTAP in both powder-to-gel ratios showed high pH and low solubility. The increase in the powder ratio decreased the setting time and flow. These findings are important regarding the proper consistency and work time to clinical application.
The Effects of Mouthwashes on the Color Stability of Resin-Based Restorative Materials
Authors: Ertürk-Avunduk Ayşe Tuğba , Aksu Seçkin , Delikan Ebru
Published: July 2020

Objective: This study investigated the effects of three types of mouthwash on the color stability of three resin-based restorative materials (nanohybrid resin composite, sonic-activated bulk-fill material, and compomer). Materials and Methods: To this end, 120 cylindrical disc specimens were prepared and polished, after which they were incubated in distilled water for 24 hours for post-polymerization. The baseline color values of each specimen were measured with a spectrophotometer, then the specimens were randomly divided into four groups. Following immersion in the mouthwashes for 24 hours, the specimens were rinsed with distilled water and dried before the color measurement was repeated. The values of color change (∆E₀₀) were subsequently calculated. A two-way analysis of variance and Duncan’s post hoc multiple comparison tests were conducted to determine statistically significant differences among the restorative materials. Results: All samples showed discoloration after immersion, albeit some instances of discoloration were imperceptible. In this respect, a statistically significant difference was found among the restorative materials and mouthwashes (p<0.05). Imperceptible ∆E₀₀ values were derived on the nanohybrid resin composite and compomer, but perceptible and acceptable ∆E₀₀ values were detected on the sonic-activated bulk-fill materials (p<0.05). The clinically unacceptable discoloration was observed on the sonic-activated bulk-fill composite immersed in Listerine®. Conclusions: Clinicians should make recommendations based on the potential staining capacity of mouthwashes prescribed for daily use in restorative materials. In this way, the need for renewal of restorations due to discoloration could be avoided.
PERSPECTIVAS ECOFEMINISTAS Y ECOSOCIALISTAS SOBRE EL CAOS DEL CAMBIO CLIMÁTICO: AMENAZAS A LA MADRE TIERRA
Authors: Isla Ana
Published: July 2020

El objetivo de este texto es articular el cambio climático, las causas de su origen y las posibilidades de superar esta crisis. El desarrollo de este documento se basa en las investigaciones de la autora y en el curso de Environmental Justice de la Brock University. Este curso presenta la perspectiva ecofeminista, la cual sostiene que el proceso de reproducción de la vida ha ocurrido por millones de años sin mayor alteración, sin embargo con el proceso de producción de mercancías que usa el combustible fósil, el monóxido de carbono (C02) se acumula rápidamente en la atmósfera, creando la crisis del ecosistema. Para finalizar se presentan algunas perspectivas que proponen la Justicia Social como salida de la crisis ecosistémica.
LA INVESTIGACIÓN ACCIÓN PARTICIPATIVA (IAP) EN EL MARKETING POLÍTICO 3.0. LA INTELIGENCIA EMOCIONAL INTRAPERSONAL E INTERPERSONAL EN EL CASO DE PODEMOS Y CIUDADANOS
Authors: Reyero Simón Laura , Cordero Verdugo Raquel Rebeca , Vargas Delgado José Jesús
Published: July 2020

Este artículo evidencia que la aplicación de la metodología de la Investigación Acción Participativa (IAP) es apropiada y útil como instrumento de investigación de mercados para el marketing, aplicación cuya validez solo era reconocida en el ámbito de la educación, a excepción de algunos autores como Moreno (2005). La investigación base de este artículo, realizada entre los años 2014 y 2016, confirmó la creación y la consolidación de un nuevo paradigma: el Marketing Político 3.0.
Unilateral segmental aplasia of uterine horn associated with pyometra and vulvar hypoplasia in a bitch
Authors: Antonov A.
Published: July 2020

The aim of this report was to describe a clinical case of unilateral segmental aplasia of the uterine horn and vulvar hypoplasia associated with pyometra as a complication in a bitch. The patient was presented with abdominal pain, excessive vulvar licking, anorexia and lethargy. The vulva was found hypoplastic, flushed and without any discharge. Ultrasonography revealed an enlarged tip of the left uterine horn filled with fluid. Blood laboratory analysis showed a marked leukocytosis, so diagnosis of pyometra was made. Laparotomy and ovariohysterectomy were performed. During the operation unilateral segmental aplasia of the right uterine horn was observed. This is a very rare case of segmental aplasia of the uterus associated with hypoplasia of the vulva and with clinical signs of systemic disease in the bitch.
Effect of phase-change materials on the hydration and mineralogy of cement mortar
Authors: Snehal Kusumadhar , Das Bibhuti Bhusan
Published: July 2020

The influence of direct incorporation of thermally efficient phase-change materials (PCMs) on the hydration and mineralogical properties of cement mortar was investigated. To assess the viability of bulk addition of PCMs to a cementitious system, tests of the early age, hydration, mechanical, durability and mineralogical properties were carried out. Organic PCMs showed an increase in setting time, while inorganic materials exhibited fast setting characteristics. Surface temperature was also found to be lower for cement paste with incremental dosages of PCM. However, chemical shrinkage was found to be reduced in the presence of PCM except for the inorganic type. It was observed from the results that PCMs negatively influenced the rate of strength development of a cementitious mortar. The slow rate of strength development was found to be attributed to interrupted hydration, which was confirmed through mineralogical studies. Further, from the thermo-gravimetric analysis, it was observed that the presence of PCMs in a cementitious system increased calcium hydroxide content and reduced the content of water related to hydration products.
Microsimulation-based framework to analyse urban signalised intersection in mixed traffic
Authors: Mondal Satyajit , Gupta Ankit
Published: July 2020

Microscopic traffic simulation is a powerful tool for studying complex traffic systems when analytical or empirical approaches cannot define response patterns adequately and accurately. The application of simulation techniques for evaluating the characteristics of controlled intersections is effective due to their quick and reliable outcomes. This paper presents a methodology for model development and a unique calibration process for mixed traffic streams using the widely used simulation software Vissim. An isolated signalised intersection was selected for the model development. Most of the calibration methodologies described in previous literature were based on informal practices based on a homogeneous traffic stream. This study frames a novel calibration process suitable for mixed traffic streams. The validity of the proposed methodology was evaluated using field data from another signalised intersection by means of a feasibility comparison of field data and simulation outputs. The calibrated parameters produced suitable simulation outputs, with the measure of effectiveness matching the result obtained from actual field conditions. In contrast, simulations with default or best-guess parameters resulted in significant discrepancies between the observed and simulated outputs.
Estilo de aprendizaje y nivel de pensamiento: una apuesta por el rendimiento académico en estudiantes de enfermería de una universidad privada
Authors: Prada-Reyes Sandra , Bilbao-Ramírez Jorge , Lastre-Amell Gloria , Jinete-Acendra Janeth , Manuel -Ferrer Ana
Published: July 2020

Objetivo: relacionar el estilo de aprendizaje, el nivel de pensamiento y el rendimiento académico en los estudiantes de Enfermería de primero a octavo semestre. Método: estudio cuantitativo, descriptivo y correlacional, de acuerdo con el estilo de aprendizaje propuesto por Kolb, prueba de pensamiento lógico (Tolt) y el promedio de calificaciones por semestre. La muestra fue de 381 estudiantes de I a VIII semestre, a quienes se les aplicó el Test de Comparación Múltiple LSD (Least Significant Difference), se graficaron los intervalos de confianza del rendimiento asociados a cada estilo de aprendizaje. Resultados: se evidenció que el estilo de aprendizaje Convergente – Asimilador, obtuvo el rendimiento promedio más alto y el estilo Acomodador – Divergente, presentó el rendimiento promedio más bajo. El nivel de pensamiento “Transicional” fue el que obtuvo el rendimiento promedio más alto y el nivel de pensamiento “Concreto” fue el que presentó un rendimiento promedio más bajo. Discusión y Conclusiones: los estilos de aprendizaje y los niveles de pensamiento si influyen en el rendimiento académico, pero también existe una diversidad de factores que contribuyen al rendimiento académico aceptable de los estudiantes.
Didactics: Methodological Basis of Motor Learning in Children and Adolescents
Authors: Khudolii Oleg , Iermakov Sergii , Bartik Pavol
Published: July 2020

The purpose of the study was to determine the impact of knowledge considered as a methodological basis of motor learning on the effectiveness of motor skills development in children and adolescents. Materials and methods. Young gymnasts aged 7-13 participated in the experiment. At the first stage – young gymnasts aged 8 (16 groups of 6 people each). At the second stage – young gymnasts aged 8 (3 groups of 6 people each), young gymnasts aged 13 (2 groups of 6 people each). Both philosophical and general scientific research methods were used to solve the tasks set, among which were: dialectical method, systems approach, modeling, pedagogical experiment organized according to the scheme of a 2k factorial experiment. Results. A positive effect of learning depends on the consistent solution of learning tasks and rational application of methods. This is indicated by the following: firstly, the total impact of factors reduces the number of repetitions when teaching young gymnasts a side handspring (by 23 repetitions), secondly, the total interaction increases the duration of training by 9 repetitions. Obviously, studying the decomposition of learning tasks can improve the effectiveness of learning in general. Conclusions. The learning process structure is most influenced by the conclusions of the theory of functional systems (43%, p < 0.001), the theory of movement construction (41%, p < 0.001), and the theory of management of knowledge acquisition, formation of actions and concepts (2.6%, p < 0.05). A positive effect of learning depends on the consistent solution of learning tasks and rational application of methods.
EFFICIENCY OF BIOMETRIC RECOGNITION TECHNOLOGY BASED ON TYPING DYNAMICS IN MOOC
Authors: MEDINA-LABRADOR Manuel , GOMEZ-ZERMENO Marcela Georgina , DE LA GARZA Lorena Aleman
Published: July 2020

One of the problems that require a solution in Massive Open Online Courses (MOOC) is the lack of identification and authentication of the students. Different investigations have been carried out through several navigation, physiological and behavioral methods, achieving different recognition scales. Biometric authentication by keystroke patterns (Ups&Downs) has been implemented in several MOOCs for the ease of the digital platforms of the offeror to solve the identification problem. The objective of this research is to analyze the independence of the keystroke tool of the other demographic, sociographic and behavioral variables within a MOOC, establishing an initial pattern, and two authentication measurements throughout the course. The results show that the keystroke is independent of the analyzed variables, and it is reliable to identify the students in qualitative tests with extension answers.
FROM MEDIA LITERACY TO NEW MEDIA LITERACY: A LENS INTO OPEN AND DISTANCE LEARNING CONTEXT
Authors: UGURHAN Y. Zafer Can , GENC KUMTEPE Evrim , KUMTEPE Alper Tolga , SAYKILI Abdullah
Published: July 2020

Media literacy, which traditionally aims to help individuals become better-informed users through proper consumption of media messages, has historically been reshaped to reflect the characteristics of the tools that individuals utilize to consume such messages. Information and Communication Tools (ICT) developed in the 21st century, also referred to as the Digital Age, have enabled individuals to become producers of media messages in addition to consumers. Therefore, there has been a need for empirical studies into the concept of media literacy that has evolved into new media literacy with the impact of these new participatory and connective technologies. Within this regard, this study seeks to investigate the new media literacy levels of open and distance learners who primarily depend on ICT to access tertiary education. Besides, the study examines the relationship between demographic information of learners and their new media literacy skills.
Molecular aspects of basic innate immunity in Hordeum vulgare L.
Authors: Dobryakova Ksenia S. , Voitsekhovskaja Olga
Published: July 2020

Basic innate immunity in plants is achieved via interactions between highly conserved pathogen-associated molecular structures and plant pattern recognition receptors, leading to elicitation of signaling cascades triggering molecular and cell defense mechanisms. At present, most of the components of basic innate immunity in barley have not been identified yet. Here, an overview of current knowledge on mechanisms underlying innate immunity in cereals is presented, based mostly on the data obtained for representatives of Triticeae and Oryzaeae, with a focus on the relationship between immunity, induction of autophagy and elicitation of programmed cell death during the defense response in barley.
Histomorphological analysis and clinical correlation of neoplastic and non neoplastic skin lesions: a study in a tertiary care centre of Western Uttar Pradesh, India
Authors: Bisht Mithila , Arya Anjana , Choudhry B. C.
Published: July 2020

Background: Clinical examination may suffice in making diagnosis of most dermatologic disorders but histopathological examination is often required to confirm the diagnosis and further categorize the lesions. Authors carried out this study to analyse the demographic and histomorphological characteristics of skin lesions, to determine the frequency of various dermatological disorders in the region and to evaluate the agreement between clinical and histopathological diagnosis.Methods: Punch biopsies of skin lesions received in histopathology section, were included in the study. Cases over a period of six months were analysed. Clinical details were recorded and histopathological analysis done. Special stains were applied wherever required.Results: Of the 120 cases studied, maximum cases fell in the category of 31-40 years, with male predominance.  Authors observed wide variety of non-neoplastic and neoplastic lesions. Infectious diseases were the most common of all pathologies. Leprosy was the most common histopathological diagnosis. Complete clinicopathologic correlation was seen in 51.67% of cases while partial correlation was noted in 23.33% making a total of 75%. 25% histopathological diagnosis were inconsistent with the clinical diagnosis.Conclusions: Histopathology is a gold standard investigation and plays a very important role in confirmation of clinical diagnosis of various skin lesions. Punch biopsy is a relatively easy outpatient procedure to perform.
Management of complex hepatic abscess by percutaneous catheter drainage: a case report
Authors: Pareek Prashant , Pareek Priyanka , Singh Pratish Kumar
Published: July 2020

Liver abscesses are a commonly encountered pathology in the tropical setting. Most commonly these are secondary to amoebic infestation. Majority of liver abscesses present with abdominal pain confined to the right hypochondrium. Smaller abscesses are easily dealt with by needle aspiration or catheter drainage under image guidance. Larger and complex abscesses are commonly dealt with by surgical drainage. We deal here with a case of complex liver abscesses which even had perforated into the pleural cavity. Keeping a close watch on the patient’s general condition which was satisfactory, we did not rush into a major surgical procedure. Wide antibiotic coverage and pulmonary care were initiated. Two pig-tail catheters were placed in separate abscesses and metronidazole irrigation periodically done. The daily drain output gradually reduced and we could successfully remove the two catheters at an interval. The patient made a good recovery and continues to do well on follow-up. We see in this case that even large and multiple abscesses if meticulously managed, surgical drainage can be avoided and catheter drainage provides satisfactory results. Good antibiotic coverage must continue in the follow-up period too.
Conhecimentos sobre enteroparasitoses entre gestantes atendidas em uma unidade de saúde de Maceió - AL em 2017
Authors: Silva Janaila Cristina Barbosa da , Oliveira Jéssica Alves Silva , Silva Marcia Marques da , Dias Daysa Alves , Silva Sandra Regina Guimarães , Albuquerque André Limeira Tenório de , Rocha Thiago José Matos
Published: July 2020

As infecções parasitárias podem causar a morte do infectado dependendo do grau de patogenicidade, o que justifica a investigação do conhecimento sobre essas enfermidades em grupos de risco específicos, como gestantes. Assim, este estudo teve como objetivo avaliar o conhecimento sobre enteroparasitoses entre gestantes atendidas em uma unidade de saúde de Maceió – AL. Para tal, foi realizado um estudo transversal descritivo, com uma amostra não probabilística por conveniência de 100 gestantes em acompanhamento pré-natal. Os dados foram coletados por meio de questionário padronizado, no período de fevereiro a julho de 2017. O grau de escolaridade não influenciou o conhecimento sobre as enteroparasitoses avaliadas. Cerca de 54% das gestantes afirmaram possuir o hábito de sempre lavar as mãos antes das refeições e após ir ao banheiro. O consumo de frutas e hortaliças foi prevalente, e 37% afirmaram higienizá-las com vinagre ou água sanitária, mas 87% afirmaram consumir carne malpassada. Aproximadamente 80% recebiam o abastecimento de água encanada, e 47% utilizavam água mineral para ingestão. Apesar dos avanços na assistência pré-natal na última década, a falta de conhecimento entre gestantes acerca de parasitoses se configura como fator de risco para infecção parasitária; nesse sentido, torna-se necessária a realização de atividades de educação em saúde para esse grupo, esclarecendo formas de transmissão e prevenção relacionadas às enteroparasitoses.
The effect of water transposition on the quality of water in a tropical reservoir, São Paulo – Brazil
Authors: Conserva Regiane Oliveira , Arruda Regina De Oliveira Moraes , Azevedo Fernanda Dall'Ara , Saad Antonio Roberto , Rosini Edna Ferreira
Published: July 2020

The aim of the present study is to analyze the influence of water transposition from Rio Grande System on the quality of water in Taiçupeba Reservoir, Suzano city, SP. Water samples were collected every two months for one year (from June 2016 to April 2017) in four sampling spots. Physical, chemical and biological water analyses were carried out; Water Quality and Trophic State indices were also applied. There was influence of water transposition from Rio Grande System on the quality of the water in Taiaçupeba Reservoir throughout the assessed period. The quality of the water was similar in all sampling spots, except for P3, which recorded the worst results. Point 3 was located in an urbanized zone of Taiaçupeba sub-basin; therefore, it is likely that the worse water quality in this spot has resulted from contamination by domestic sewage. It is recommended to carry out further studies based on longer sampling period in the same environment.
Tecnologia Assistiva no processo de ensino-aprendizagem de Surdos
Authors: Silva Queila Pahim da , Mendes Núbia Flávia Oliveira , Santos Sylvana Karla da Silva de Lemos
Published: July 2020

O presente artigo tem como objetivo identificar a importância da Tecnologia Assistiva na educação de Surdos em uma instituição de ensino da Rede Federal de Educação Profissional e Tecnológica. Trata-se de um estudo de caso, com pesquisa bibliográfica e a aplicação de entrevista com questionário a quatro setores da instituição: gestão, docência, estudantes Surdos e um Tradutor/Intérprete de Língua de Sinais. Os resultados indicam que, apesar da difusão e popularização das mídias sociais, há diferenças no entendimento dos respondentes quanto à Tecnologia Assistiva (TA), o que reflete a falta de efetivação entre o que a gestão percebe ser feito a favor dos estudantes Surdos pelo uso da TA, o que o professor acredita estar fazendo para esses estudantes e o que o Tradutor e Intérprete de Língua de Sinais e os discentes Surdos vivenciam na sala de aula.
Effect of Refined Nutrition Management on Nutritional Status of Patients with Decompensated Liver Cirrhosis
Authors: Li Weiying , Li Yusi , Liu Min , Gao Liangqing , Zhou Yujing
Published: July 2020

Objective: To analyze the effect of refined nutrition management on nutritional status of patients with decompensated liver cirrhosis. Methods: 100 cases of patients with decompensated liver cirrhosis treated in the author's hospital from August 2018 to December 2019 were selected. The patients were divided into the control group and the observation group randomly and they were given routine nursing management and refined nutrition management respectively. The nutritional status of the patients in the two groups was compared. Results: The post-intervention level of albumin, hemoglobin and prealbumin in the observation group was significantly higher than those in the control group after intervention, while total bilirubin was significantly lower than that in the control group, p < 0.05. Conclusion: The application of refined nutrition management in patients with decompensated liver cirrhosis can promote the improvement of nutritional status of the body, which has the value of further promotion and implementation.
Neurological Involvement with COVID-19 Review
Authors: Mochan Andre , Modi Girish
Published: July 2020

The available literature on neurological disorders reported in the context of the current COVID-19 pandemic documents an array of manifestations affecting the central nervous system (CNS), the peripheral nervous system (PNS) and muscle. These are based on case reports and small number series mainly from Wuhan, northern Italy and New York. A dearth of knowledge exists in the understanding of whether the neurological manifestations are caused by or merely associations with COVID-19 infection.

CNS involvement is observed more commonly, and includes headache, decreased level of consciousness, seizures, encephalopathy and disturbance of smell and taste. The latter has emerged as a prominent often early symptom and is considered an indicator of the neurotropic properties of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The profound and often times fatal respiratory failure associated with severe COVID-19 possibly has a neurogenic component with involvement of respiratory brainstem nuclei as a result of transneural viral spread from olfactory or bronchopulmonary receptor nerve endings progressing to the medullary respiratory centres. A generalised endotheliitis and prothrombotic inflammatory state leads to cerebrovascular complications with ischaemic strokes (often large vessel), intracerebral haemorrhage and occasionally cerebral venous thrombosis. Acute haemorrhagic necrotising encephalopathy has been described as a neurological manifestation of the cytokine storm. Postinfectious myelitis has been documented. The PNS involvement includes cases of Guillain–Barré syndrome and some of its variants or formes frustes; myositis of varying degree and severity is encountered.

Direct viral neurotropic disorders need to be distinguished from secondary neurological disease resulting from systemic multi-organ illness and from mere coincidental co-occurrence of COVID-19 and a neurological condition. Future clinicopathological studies will need to clarify some of these questions.