bluuebunny/crossref_metadata_2025 huggingface dataset:
Cross-core Data Sharing for Energy-efficient GPUs
Authors: Falahati Hajar , Sadrosadati Mohammad , Xu Qiumin , Gómez-Luna Juan , Saber Latibari Banafsheh , Jeon Hyeran , Hesaabi Shaahin , Sarbazi-Azad Hamid , Mutlu Onur , Annavaram Murali , Pedram Masoud
Published: March 2024

Graphics Processing Units (GPUs) are the accelerator of choice in a variety of application domains, because they can accelerate massively parallel workloads and can be easily programmed using general-purpose programming frameworks such as CUDA and OpenCL. Each Streaming Multiprocessor (SM) contains an L1 data cache (L1D) to exploit the locality in data accesses. L1D misses are costly for GPUs for two reasons. First, L1D misses consume a lot of energy as they need to access the L2 cache (L2) via an on-chip network and the off-chip DRAM in case of L2 misses. Second, L1D misses impose performance overhead if the GPU does not have enough active warps to hide the long memory access latency. We observe that threads running on different SMs share 55% of the data they read from the memory. Unfortunately, as the L1Ds are in the non-coherent memory domain, each SM independently fetches data from the L2 or the off-chip memory into its L1D, even though the data may be currently available in the L1D of another SM. Our goal is to service L1D read misses via other SMs, as much as possible, to cut down costly accesses to the L2 or the off-chip DRAM. To this end, we propose a new data-sharing mechanism, called
Cross-Core Data Sharing (CCDS)
. CCDS employs a predictor to estimate whether the required cache block exists in another SM. If the block is predicted to exist in another SM’s L1D, then CCDS fetches the data from the L1D that contain the block. Our experiments on a suite of 26 workloads show that CCDS improves average energy and performance by 1.30× and 1.20×, respectively, compared to the baseline GPU. Compared to the state-of-the-art data-sharing mechanism, CCDS improves average energy and performance by 1.37× and 1.11×, respectively.
Unravelling the Mechanism of Electrochemically Induced Sol-Gel Depositions: pH Profiles Near Electrode and Influence on Film Growth
Authors: Vanheusden Genis , De Taeye Louis , Blom Martijn J. W. , Jobbagy Matias , Vereecken Philippe M.
Published: March 2024

Electrochemically induced sol-gel depositions have become a widespread, versatile method for fabricating hybrid and nanostructured oxides on conductive substrates. The process is based on the buildup of electrochemically generated OH− in the diffusion layer near the electrode surface. For the electrodeposition of silica thin films, these OH− ions catalyze the gelation of a kinetically stable precursor solution, thereby resulting in an electrochemically controlled process. The control of the diffusion layer has proven pivotal to depositing thin films while preventing the formation of aggregated by-products deeper in the solution. In this work, the silica sol-gel reactions and electrochemical OH− generation were critically analyzed and described to gain insight into the deposition mechanism. A general model is proposed that predicts the pH profile during both stationary and rotating disk electrode depositions under different conditions (i.e., current densities, times, and rotation rates). This model provides insights into the reactive zones where gelation occurs, and explains typical phenomena observed during deposition such as the dependence of film growth rates and aggregate formation on the deposition conditions. The insights and expressions obtained in this work are invaluable when designing future experiments using novel chemistries or setups.
Sex differences in the purinergic 2 receptor-mediated blood pressure response to treadmill exercise in rats with simulated peripheral artery disease
Authors: Butenas Alec L. E. , Flax Joseph S. , Carroll Raimi J. , Chuwonganant C. Shane , Baranczuk Ashley M. , Copp Steven W.
Published: March 2024

Here, we demonstrate that purinergic 2 (P2) receptors contribute significantly to the blood pressure response to treadmill exercise in male rats both with and without simulated PAD induced by femoral artery ligation. We found no role for P2 receptors in the blood pressure response to treadmill exercise in female rats, thus revealing clear sex differences in P2 receptor-mediated blood pressure control during exercise.
Nerve transfer for restoration of lower motor neuron-lesioned bladder, urethral and anal sphincter function. Part 4: Effectiveness of the motor reinnervation
Authors: Tiwari Ekta , Porreca Danielle S. , Braverman Alan S. , Holt-Bright Lewis , Frara Nagat A. , Brown Justin M. , Johnston Benjamin R. , Bazarek Stanley F. , Hilliard Brendan A. , Mazzei Michael , Pontari Michel A. , Yu Daohai , Ruggieri Michael R. , Barbe Mary F.
Published: March 2024

This data supports the use of nerve transfer techniques for the restoration of bladder function.
Detection of Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus in Inactivated Fermented Milk Using Fluorescence Quantitative Loop-Mediated Isothermal Amplification
Authors: Zhou Shuaikang , Hu Lianxia , Xue Yuling , Zhang Dong , Song Baokuo , Wang Mengyang , Yuan Qingbin , Ning Yibing , Wang Shijie
Published: March 2024

Currently, no effective method exists to detect and monitor fermentation probiotics and evaluate the quality of inactivated fermented milk. Therefore, in this study, a fluorescence quantitative loop-mediated isothermal amplification (FQ-LAMP) method was developed to detect Lactobacillus delbrueckii subsp. bulgaricus and Streptococcus thermophilus. The specificity of LAMP primers for L. bulgaricus and S. thermophilus was verified using S-type amplification curves and a single peak at approximately 88.568°C and 83.704°C of the melting curves, respectively. The lowest quantification limits of FQ-LAMP for the two strains in inactivated fermented milk were 8.1 × 103 CFU/g (170 fg/μL) and 6.8 × 103 CFU/g (170 fg/μL), respectively. FQ-LAMP was used to analyse 40 inactivated fermented milk samples from six randomly selected brands. The logarithmic concentration of S. thermophilus in all products was between 7.482 and 8.936. The logarithmic concentration of L. bulgaricus ranged from 4.590 to 8.277, with no detectable L. bulgaricus in three samples. FQ-LAMP has the potential as a rapid, specific, and accurate method for detecting and monitoring L. bulgaricus and S. thermophilus in inactivated fermented milk during their shelf life.
Noninvasive Stratification of Colon Cancer by Multiplex PET Imaging
Authors: Malviya Gaurav , Lannagan Tamsin R.M. , Johnson Emma , Mackintosh Agata , Bielik Robert , Peters Adam , Soloviev Dmitry , Brown Gavin , Jackstadt Rene , Nixon Colin , Gilroy Kathryn , Campbell Andrew , Sansom Owen J. , Lewis David Y.
Published: March 2024

Purpose:

The current approach for molecular subtyping of colon cancer relies on gene expression profiling, which is invasive and has limited ability to reveal dynamics and spatial heterogeneity. Molecular imaging techniques, such as PET, present a noninvasive alternative for visualizing biological information from tumors. However, the factors influencing PET imaging phenotype, the suitable PET radiotracers for differentiating tumor subtypes, and the relationship between PET phenotypes and tumor genotype or gene expression–based subtyping remain unknown.

Experimental Design:

In this study, we conducted 126 PET scans using four different metabolic PET tracers, [18F]fluorodeoxy-D-glucose ([18F]FDG), O-(2-[18F]fluoroethyl)-l-tyrosine ([18F]FET), 3′-deoxy-3′-[18F]fluorothymidine ([18F]FLT), and [11C]acetate ([11C]ACE), using a spectrum of five preclinical colon cancer models with varying genetics (BMT, AKPN, AK, AKPT, KPN), at three sites (subcutaneous, orthograft, autochthonous) and at two tumor stages (primary vs. metastatic).

Results:

The results demonstrate that imaging signatures are influenced by genotype, tumor environment, and stage. PET imaging signatures exhibited significant heterogeneity, with each cancer model displaying distinct radiotracer profiles. Oncogenic Kras and Apc loss showed the most distinctive imaging features, with [18F]FLT and [18F]FET being particularly effective, respectively. The tissue environment notably impacted [18F]FDG uptake, and in a metastatic model, [18F]FET demonstrated higher uptake.

Conclusions:

By examining factors contributing to PET-imaging phenotype, this study establishes the feasibility of noninvasive molecular stratification using multiplex radiotracer PET. It lays the foundation for further exploration of PET-based subtyping in human cancer, thereby facilitating noninvasive molecular diagnosis.
Supplemental Figure S5 from Targeting Tryptophan Catabolism in Ovarian Cancer to Attenuate Macrophage Infiltration and PD-L1 Expression
Authors: Crump Lyndsey S. , Floyd Jessica L. , Kuo Li-Wei , Post Miriam D. , Bickerdike Mike , O'Neill Kathleen , Sompel Kayla , Jordan Kimberly R. , Corr Bradley R. , Marjon Nicole , Woodruff Elizabeth R. , Richer Jennifer K. , Bitler Benjamin G.
Published: March 2024

Tryptophan catabolism pathway regulation of PD-L1 expression.
Supplementary Methods from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer
Authors: Karanth Shama , Osazuwa-Peters Oyomoare L. , Wilson Lauren E. , Previs Rebecca A. , Rahman Fariha , Huang Bin , Pisu Maria , Liang Margaret , Ward Kevin C. , Schymura Maria J. , Berchuck Andrew , Akinyemiju Tomi F.
Published: March 2024

Additional description of data sources and statistical methods
FIGURE 4 from Targeting Tryptophan Catabolism in Ovarian Cancer to Attenuate Macrophage Infiltration and PD-L1 Expression
Authors: Crump Lyndsey S. , Floyd Jessica L. , Kuo Li-Wei , Post Miriam D. , Bickerdike Mike , O'Neill Kathleen , Sompel Kayla , Jordan Kimberly R. , Corr Bradley R. , Marjon Nicole , Woodruff Elizabeth R. , Richer Jennifer K. , Bitler Benjamin G.
Published: March 2024

A dual IDO1/TDO2 inhibitor reduces macrophage tumor infiltration. A, Murine ID8 tumor study design. Representative ID8 tumor images (B), MRI (dotted lines; C), and tumor weight (n = 7–9/group; D). E, ID8 tumor volume. F, KYN levels in mouse serum. Blinded binning of T cells (CD3+; G) and macrophage (F4/80+; H) infiltration from ID8 tumors. I, mIHC panel used on ID8 mouse tumors. J, mIHC analysis of mouse ID8 tumors. K, In the human ovarian cancer TCGA dataset, TIMERv2 analysis of TDO2 and “M2” protumor macrophage infiltration. L, mIHC analysis of primary HGSC human tumors. Representative images. Quantification of tumor-associated cytotoxic T cells (M), Tregs (N), and macrophages (O) based on IL6 status of primary HGSC human tumors. Error bars, SEM. Statistical test, unpaired t test and unpaired t test with Welch correction (M–O). *, P < 0.05; **, P < 0.01; ****, P < 0.0001
Data from Targeting Tryptophan Catabolism in Ovarian Cancer to Attenuate Macrophage Infiltration and PD-L1 Expression
Authors: Crump Lyndsey S. , Floyd Jessica L. , Kuo Li-Wei , Post Miriam D. , Bickerdike Mike , O'Neill Kathleen , Sompel Kayla , Jordan Kimberly R. , Corr Bradley R. , Marjon Nicole , Woodruff Elizabeth R. , Richer Jennifer K. , Bitler Benjamin G.
Published: March 2024

Abstract
High-grade serous carcinoma (HGSC) of the fallopian tube, ovary, and peritoneum is the most common type of ovarian cancer and is predicted to be immunogenic because the presence of tumor-infiltrating lymphocytes conveys a better prognosis. However, the efficacy of immunotherapies has been limited because of the immune-suppressed tumor microenvironment (TME). Tumor metabolism and immune-suppressive metabolites directly affect immune cell function through the depletion of nutrients and activation of immune-suppressive transcriptional programs. Tryptophan (TRP) catabolism is a contributor to HGSC disease progression. Two structurally distinct rate-limiting TRP catabolizing enzymes, indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase 2 (TDO2), evolved separately to catabolize TRP. IDO1/TDO2 are aberrantly expressed in carcinomas and metabolize TRP into the immune-suppressive metabolite kynurenine (KYN), which can engage the aryl hydrocarbon receptor to drive immunosuppressive transcriptional programs. To date, IDO inhibitors tested in clinical trials have had limited efficacy, but those inhibitors did not target TDO2, and we find that HGSC cell lines and clinical outcomes are more dependent on TDO2 than IDO1. To identify inflammatory HGSC cancers with poor prognosis, we stratified patient ascites samples by IL6 status, which correlates with poor prognosis. Metabolomics revealed that IL6-high patient samples had enriched KYN. TDO2 knockdown significantly inhibited HGSC growth and TRP catabolism. The orally available dual IDO1/TDO2 inhibitor, AT-0174, significantly inhibited tumor progression, reduced tumor-associated macrophages, and reduced expression of immune-suppressive proteins on immune and tumor cells. These studies demonstrate the importance of TDO2 and the therapeutic potential of AT-0174 to overcome an immune-suppressed TME.
Significance:
Developing strategies to improve response to chemotherapy is essential to extending disease-free intervals for patients with HGSC of the fallopian tube, ovary, and peritoneum. In this article, we demonstrate that targeting TRP catabolism, particularly with dual inhibition of TDO2 and IDO1, attenuates the immune-suppressive microenvironment and, when combined with chemotherapy, extends survival compared with chemotherapy alone.
Measuring Objective and Subjective Sleep during Lisdexamfetamine Treatment of Acute Methamphetamine Withdrawal: A Feasibility Study
Authors: Acheson Liam S. , Gordon Christopher , McKetin Rebecca , Brett Jonathan , Christmass Michael , Rodgers Craig , Lintzeris Nicholas , Dunlop Adrian , Farrell Michael , Shoptaw Steven , Ezard Nadine , Siefried Krista J.
Published: March 2024

Introduction: Sleep disturbance is common during methamphetamine (MA) use and withdrawal; however, the feasibility of combined subjective-objective measurement of sleep-wake has not been shown in this population. Actigraphy is a well-established, non-invasive measure of sleep-wake cycles with good concordance with polysomnography. This study aimed to investigate the feasibility and utility of using actigraphy and sleep diaries to investigate sleep during MA withdrawal. Methods: We conducted a feasibility and utility study of actigraphy and sleep diaries during a clinical trial of lisdexamfetamine for MA withdrawal. Participants were inpatients for 7 days, wore an actigraph (Philips Actiwatch 2) and completed a modified Consensus Sleep Diary each morning. Participants were interviewed between days 3–5. Results: Ten participants (mean age 37 years, 90% male) were enrolled. No participant removed the device prematurely. Participants interviewed (n = 8) reported that the actigraph was not difficult or distracting to wear or completion of daily sleep diary onerous. Actigraphic average daily sleep duration over 7 days was 568 min, sleep onset latency 22.4 min, wake after sleep onset (WASO) 75.2 min, and sleep efficiency 83.6%. Sleep diaries underreported daily sleep compared with actigraphy (sleep duration was 56 min (p = 0.008) and WASO 47 min (p < 0.001) less). Overall sleep quality was 4.4 on a nine-point Likert scale within the diary. Conclusions: Continuous actigraphy is feasible to measure sleep-wake in people withdrawing from MA, with low participant burden. We found important differences in self-reported and actigraphic sleep, which need to be explored in more detail.
Gastrointestinal Variant of Lemierre Syndrome due to Fusobacterium nucleatum: A Case Report
Authors: Salam Reshad , Verma Abhiroop , Noeske Michael , Alnimer Lynna , Sieloff Eric M. , Piper Marc S.
Published: March 2024

Introduction: Pyogenic liver abscess is a noteworthy health concern in North America, characterized by a mortality rate ranging from 2 to 12%. This condition is often polymicrobial, with Streptococcus species and Escherichia coli as the predominant causal pathogens in Western countries. Fusobacterium species, typically commensals of gastrointestinal, genital, and oral flora, have been implicated in the rare formation of tonsillar abscesses and Lemierre syndrome, including its gastrointestinal variant known as pylephlebitis. Case Presentation: We present the case of an immunocompetent male with a 2-week history of abdominal distention and pain. Abdominal magnetic resonance imaging revealed multiseptated cystic hepatic masses and portal vein thrombosis. A subsequent liver biopsy confirmed Fusobacterium nucleatum etiology. The patient was initiated on intravenous cefepime and oral metronidazole antibiotics. Unfortunately, the patient succumbed to cardiac arrest before a final diagnosis could be established. Conclusion: Fusobacterium species-associated liver abscess, coupled with the rare gastrointestinal variant of Lemierre syndrome (pylephlebitis), poses a significant mortality risk. This case underscores the rarity and clinical challenges associated with these conditions. Increased awareness among clinicians is crucial for early diagnosis and prompt intervention, potentially improving outcomes in such cases.
Lenalidomide Treatment of Isolated Central Nervous System Relapse in Acute Lymphoblastic Leukemia after Hematopoietic Stem Cell Transplantation and Chimeric Antigen Receptor T-Cell Therapy
Authors: Zhang Qing , Dong Yi , Zhai Zhimin , Tao Lili , Tao Qianshan
Published: March 2024

Introduction: Hematopoietic stem cell transplantation (HSCT) and chimeric antigen receptor T (CAR-T) cell are effective treatments for acute lymphoblastic leukemia (ALL). Various forms of intra- and extramedullary relapses have been reported after HSCT and CAR-T-cell therapy for ALL; however, no reports have investigated isolated central nervous system (CNS) relapse after HSCT and CAR-T-cell therapy. Hence, no clinical treatment has been established for such rare patients. Case Presentation: An 18-year-old male patient with B-cell ALL suffered from isolated CNS relapse after HSCT and CAR-T-cell therapy. Conventional systemic intravenous and intrathecal chemotherapies were ineffective and intolerable. A unique immunosuppressive microenvironment of decreasing NK cell percentage and increasing IL-8 concentration and CAR-T-cell exhaustion had been illustrated in the cerebrospinal fluid. Finally, the patient received immunomodulatory therapy with lenalidomide and obtained complete remission. Conclusion: Lenalidomide might be a therapeutic strategy for isolated CNS relapse after HSCT and CAR-T-cell therapy.
Predicting High‐Risk Fetal Cardiac Disease Anticipated to Need Immediate Postnatal Stabilization and Intervention with Planned Pediatric Cardiac Operating Room Delivery
Authors: Moray Amol , Mugaba Proscovia M. , Joynt Chloe , McBrien Angela , Eckersley Luke G. , Phillipos Ernest , Holinski Paula , Ryerson Lindsay , Coe James Yashu , Chandra Sujata , Wong Billy , Derbyshire Michele , Lefebvre Maria , Al Aklabi Mohammed , Hornberger Lisa K.
Published: March 2024

Background

Distances between delivery and cardiac services can make the care of fetuses with cardiac disease at risk of acute cardiorespiratory instability at birth a challenge. In 2013 we implemented a fetal echocardiography‐based algorithm targeting fetuses considered high risk for acute cardiorespiratory instability at ≤2 hours of birth for delivery in our pediatric cardiac operating room of our children's hospital, and, herein, examine our experience.

Methods and Results

We reviewed maternal and postnatal medical records of all fetuses with cardiac disease encountered January 2013 to March 2022 considered high risk for acute cardiorespiratory instability. Secondary analysis was performed including all fetuses with diagnoses of d‐transposition of the great arteries/intact ventricular septum (d‐TGA/IVS) and hypoplastic left heart syndrome (HLHS) encountered over the study period. Forty fetuses were considered high risk for acute cardiorespiratory instability: 15 with d‐TGA/IVS and 7 with HLHS with restrictive atrial septum, 4 with absent pulmonary valve syndrome, 3 with obstructed anomalous pulmonary veins, 2 with severe Ebstein anomaly, 2 with thoracic/intracardiac tumors, and 7 others. Pediatric cardiac operating room delivery occurred for 33 but not for 7 (5 with d‐TGA/IVS, 2 with HLHS with restrictive atrial septum). For high‐risk cases, fetal echocardiography had a positive predictive value of 50% for intervention/extracorporeal membrane oxygenation/death at ≤2 hours and 70% at ≤24 hours. Of “low‐risk” cases, 6/46 with d‐TGA/IVS and 0/45 with HLHS required intervention at ≤2 hours. Fetal echocardiography for predicting intervention/extracorporeal membrane oxygenation/death at ≤2 hours had a sensitivity of 67%, specificity 93%, and positive and negative predictive values of 80% and 87%, respectively, for d‐TGA/IVS, and 100%, 95%, 71%, and 100% for HLHS, respectively.

Conclusions

Fetal echocardiography can predict the need for urgent intervention in a majority with d‐TGA/IVS and HLHS and in half of the entire spectrum of high‐risk cardiac disease.
CircALMS1 Alleviates Pulmonary Microvascular Endothelial Cell Dysfunction in Pulmonary Hypertension
Authors: Hu Xiaoyi , Sun Yuanyuan , Wang Shang , Zhao Hui , Wei Yaqin , Fu Jiaqi , Huang Yuxia , Wu Wenhui , Li Jinling , Liu Jinming , Gong Sugang , Zhao Qinhua , Wang Lan , Jiang Rong , Song Xiao , Yuan Ping
Published: March 2024

Background

Circular RNAs can serve as regulators influencing the development of pulmonary hypertension (PH). However, their function in pulmonary vascular intimal injury remains undefined. Thus, we aimed to identify specifically expressed circular RNAs in pulmonary microvascular endothelial cells (PMECs) under hypoxia and PH.

Methods and Results

Deep RNA sequencing and quantitative real‐time polymerase chain reaction revealed that circALMS1 (circular RNA Alstrom syndrome protein 1) was reduced in human PMECs under hypoxia (
P
<0.0001). Molecular biology and histopathology experiments were used to elucidate the roles of circALMS1 in regulating PMEC dysfunction among patients with PH. The circALMS1 expression was decreased in the plasma of patients with PH (
P
=0.0315). Patients with lower circALMS1 levels had higher risk of death (
P
=0.0006). Moreover, the circALMS1 overexpression of adeno‐associated viruses improved right ventricular function and reduced pulmonary vascular remodeling in monocrotaline‐PH and sugen/hypoxia‐PH rats (
P
<0.05). Furthermore, circALMS1 overexpression promoted apoptosis and inhibited PMEC proliferation and migration under hypoxia by directly downregulating miR‐17‐3p (
P
<0.05). Dual luciferase assay confirmed the direct binding of circALMS1 to miR‐17‐3p and miR‐17‐3p binding to its target gene YT521‐B homology domain‐containing family protein 2 (YTHDF2) (
P
<0.05). The YTHDF2 levels were also downregulated in hypoxic PMECs (
P
<0.01). The small interfering RNA YTHDF2 reversed the effects of miR‐17‐3p inhibitors on PMEC proliferation, migration, and apoptosis. Finally, the results indicated that, although YTHDF2, as an N(6)‐methyladenosine reader protein, contributes to the degradation of many circular RNAs, it could not regulate the circALMS1 levels in PMECs (
P
=0.9721).

Conclusions

Our study sheds new light on circALMS1‐regulated dysfunction of PMECs by the miR‐17‐3p/YTHDF2 pathway under hypoxia and provides insights into the underlying pathogenesis of PH.
Association Between Aortic Wall Parameters on Multidetector Computed Tomography and Ruptured Plaques By Nonobstructive General Angioscopy
Authors: Miyagawa Masatsugu , Kojima Keisuke , Takahashi Kurara , Nakajima Yuki , Migita Shohei , Mizobuchi Saki , Tanaka Yudai , Fukumoto Katsunori , Arai Riku , Morikawa Tomoyuki , Mineki Takashi , Murata Nobuhiro , Sudo Mitsumasa , Fukamachi Daisuke , Okumura Yasuo
Published: March 2024

Background

Nonobstructive general angioscopy (NOGA) can identify vulnerable plaques in the aortic lumen that serve as potential risk factors for cardiovascular events such as embolism. However, the association between computed tomography (CT) images and vulnerable plaques detected on NOGA remains unknown.

Methods and Results

We investigated 101 patients (67±11 years; women, 13.8%) who underwent NOGA and contrast‐enhanced CT before or after 90 days in our hospital. On CT images, the aortic wall thickness, aortic wall area (AWA), and AWA in the vascular area were measured at the thickest point from the 6th to the 12th thoracic vertebral levels. Furthermore, the association between these measurements and the presence or absence of NOGA‐derived aortic plaque ruptures (PRs) at the same vertebral level was assessed. NOGA detected aortic PRs in the aortic lumens at 145 (22.1%) of the 656 vertebral levels. The presence of PRs was significantly associated with greater aortic wall thickness (3.3±1.7 mm versus 2.1±1.2 mm), AWA (1.33±0.68 cm
2
versus 0.89±0.49 cm
2
), and AWA in the vascular area (23.2%±9.3% versus 17.2%±7.6%) (
P
<0.001 for all) on the CT scans compared with the absence of PRs. The frequency of PRs significantly increased as the aortic wall thickness increased. Notably, a few NOGA‐derived PRs were detected on CT in near‐normal intima.

Conclusions

The presence of NOGA‐derived PRs was strongly associated with increased aortic wall thickness, AWA, and AWA in the vascular area, measured using CT. NOGA can detect PRs in the intima that appear almost normal on CT scans.
Human Capital and Climate Change
Authors: Angrist Noam , Winseck Kevin , Patrinos Harry Anthony , Zivin Joshua Graff
Published: March 2024

Addressing climate change requires individual behavior change and voter support for proclimate policies, yet surprisingly little is known about how to achieve these outcomes. In this paper, we estimate causal effects of additional education on pro-climate outcomes using new compulsory schooling law data across 20 European countries. We analyze effects on proclimate beliefs and behaviors, as well as novel data on policy preferences and voting for green parties. Results show that a year of education substantially increases pro-climate beliefs, behaviors, and policy preferences.
A new subspecies, Eumeces schneiderii barani n. ssp (Reptilia: Sauria: Scincidae) from Turkey
Authors: KUMLUTAS YUSUF , ARIKAN HÜSEYIN , ILGAZ ÇETIN , KASKA YAKUP
Published: March 2024

This study describes a new subspecies of lizard, Eumeces schneiderii barani n. ssp., from western Anatolia, Turkey. The new subspecies is differentiated from other two subspecies in Anatolia (E. s. princeps and E. s. pavimentatus) by its characteristic colour and colour-pattern as well as by the scales along the dorsal midline. Results obtained from polyacrylamide gel disc electrophoresis support this differentiation.
Jaltomata tlaxcala, a new species of the genus Jaltomata (Solanaceae, Solanoideae, Solaneae)
Authors: FLORES-SÁNCHEZ IGNACIO DARÍO , SANDOVAL-VILLA MANUEL , USCANGA-MORTERA EBANDRO , SILVA-ROJAS HILDA VICTORIA
Published: March 2024

The taxonomic status of a specimen of the genus Jaltomata recovered from the Central Highland Valley of Mexico was realized. Phylogenetic analysis was performed via Bayesian inference and maximum likelihood methods complemented with Genealogical Concordance Phylogenetic Species Recognition (GCPSR) using the PHI test. The results indicated that the specimen in study belongs to the genus Jaltomata sp. nov. supported by PHI test (φ=1.0) showing no evidence of recombination. Characteristics of corolla, pedicel and calyx, stigma, anthers, fruit, and seeds, differentiated this species. Based on the results, the name Jaltomata tlaxcala is proposed for this new species.
Lutophila gen. nov., a new diatom genus from the hottest place on Earth, Lut Desert, Iran
Authors: KHEIRI SOMAYYEH , EDLUND MARK B. , SPAULDING SARAH , NADIR SOLAK CÜNEYT , SABOURI JAFAR , IZADI BAHMAN , PESZEK ŁUKASZ
Published: March 2024

The Lut Desert is one of the world’s driest and hottest large deserts. This large basin has shallow groundwater pools that have been studied little for microbial flora, especially diatoms, and the present study is the second attempt. We report a new genus with one new species and the related morphotypes. The genus Lutophila and its type species L. iranica is found in hypersaline pools and a saline river in the Central Lut Desert depression, an area known as the hottest spot in the world. The morphology, systematic position, distribution, and ecological conditions of the new species and its morphotypes are discussed. The new genus Lutophila has a linear-lanceolate, symmetric outline with broadly rounded apices and two kinds of areolae, one on the valve face and one on the valve mantle; these characters resemble those shared by the diatom genera Krasskella, Biremis, Chamaepinnularia and Oestrupia. Lutophila iranica exhibits two morphotypes with similar outline; however, L. iranica morphotype 2 is wider than the L. iranica morphotype 1 and has a more distinctive central area.
Pseudoconiocessia xishuangbannaensis gen. et sp. nov. in Coniocessiaceae, Xylariales from Coffea liberica in China
Authors: LU LI , KARUNARATHNA SAMANTHA C. , LIU YINA , ELGORBAN ABDALLAH M. , TIBPROMMA SAOWALUCK , JAYAWARDENA RUVISHIKA S.
Published: March 2024

During a survey of saprobic fungi on coffee samples in Yunnan Province, China, in 2020 and 2022, fungal fruiting bodies on decaying Liberian coffee twigs were collected and isolated. Maximum likelihood and Bayesian analyses of combined ITS, LSU, and RPB2 genes showed that the two isolated fungal strains belonged to a distinct species in Coniocessiaceae and were well separated from closely related genera with 73% ML and 0.92 PP statistical support. Morphologically, this distinct species can be differentiated from other genera in Coniocessiaceae by aseptate hamathecium, 4–8-spored asci with a flat apical ring, and fusiform ascospores, conical at the lower end. Based on morphology and phylogenetic analyses, the two fungal strains are described as a distinct new genus Pseudoconiocessia, within Coniocessiaceae. Pseudoconiocessia is introduced here with Pseudoconiocessia xishuangbannaensis as the type species.
Two new species of Anthurium sect. Urospadix (Araceae) endemic to the restinga vegetation of Bahia, Brazil
Authors: PIMENTA KARENA M. , C. MARINHO LUCAS , M. AMORIM ANDRÉ , MAYO SIMON
Published: March 2024

Coastal vegetation will be the first areas to be directly affected by rising sea levels as a result of climate change. Thus, it is urgent to know and disseminate information about their plant diversity, especially those that are already known to be impacted by other threat factors. Here we present two new critically endangered Anthurium sect. Urospadix species from the restingas of Bahia, Brazil: A. bellissimum and A. itacarense. Descriptions, illustrations, photos in vivo, as well as discussion on the conservation status and related species are provided.
Astragalus miksensis Fırat (Fabaceae), a new species in section Hymenostegis from Van province, Türkiye
Authors: FIRAT MEHMET
Published: March 2024

Astragalus miksensis Fırat (sect. Hymenostegis Bunge), a new species is described from Bahçesaray (Miks)/Van province, Türkiye. The new species is morphologically similar to Astragalus zohrabi Bunge, from which it differs in several morphological features including stipules, leaves, peduncle, indumentum, inflorescence shape, flower, ovary, fruit and seed characters. A comprehensive description of Astragalus miksensis is provided, including detailed photographs, distribution map, habitat and ecology, vernacular names and IUCN conservation status.
Asparagus dabieshanensis (Asparagaceae), a new species from Dabie Mountains, Central China
Authors: YANG JIA-XIN , ZHU XIN-XIN , JIA NAN , HU GUANG-WAN , WANG QING-FENG
Published: March 2024

Asparagus dabieshanensis, a new species from the Dabie Mountains, Central China, is described and illustrated. Morphologically, it is similar to A. cochinchinensis (Lour.) Merr. and A. filicinus D. Don, but differs in having long and straight cladodes, and shorter pedicel than that of the last two species. Molecular phylogenetic analysis based on the combined four DNA markers (trnH-psbA, trnD-trnT, ndhF, phyC) indicated that the new species is a sister to A. cochinchinensis with strong support.
A history of systematic studies of the bees of Cuba (Insecta: Hymenoptera, Anthophila)
Authors: GENARO JULIO A.
Published: March 2024

A meticulous search was made for papers related to Cuban bees to define the historical context and periods in which studies of their taxonomy and natural history have occurred. Systematic studies of this group of insects began 230 years ago. Such studies are divided into several stages: European (1763–1896), North American (1896–1944), consolidation and current (1944–present). I present the current state of knowledge of natural history of Cuban bees, the status of the main entomological collections in the country, and experience in the use of bees as pollinators in Cuba.
Description and life cycle of the hydrozoan Hydractinia uniformis, sp. nov. (Cnidaria: Hydrozoa: Hydractiniidae), from the coast of southeastern Brazil
Authors: STAMPAR SÉRGIO N. , TRONOLONE VALQUIRIA B. , MORANDINI ANDRÉ C.
Published: March 2024

A new species of hydrozoan, assigned here to the genus Hydractinia, is described from the southeastern coast of Brazil (São Paulo state). This new species is distinguished from all known species of the genus Hydractinia by a combination of the following characters: monomorphic colonies, long tentacles of the polyp, production of frustules, and free medusae with branched mouth arms and ocelli.
A new endemic species of the subgenus Mus (Rodentia, Mammalia) on the Island of Cyprus
Authors: CUCCHI T. , ORTH A. , AUFFRAY J.-C. , RENAUD S. , FABRE L. , CATALAN J. , HADJISTERKOTIS E. , BONHOMME F. , VIGNE J.-D.
Published: March 2024

The house mouse (Mus musculus domesticus) and the short-tailed mouse of the eastern Mediterranean area (M. macedonicus) were thought to live sympatrically on Cyprus Island. Recently, a phylogenetic survey has shown that the non-commensal mouse of Cyprus was an unknown sister species of European wild mice. Here, we describe this new species of the genus Mus (Rodentia, Mammalia), namely Mus cypriacus sp. n., based on 19 specimens trapped in the southern part of Cyprus. These animals were first compared to Eurasian species of mice using both molecular genetics (complete D-loop sequences and nuclear gene intron) and cytogenetics to state on its systematic status. Then classical and geometric morphometric analyses on both cranial and dental characters have been performed to compare Mus cypriacus with circum-Mediterranean species and provide diagnositic morphological characters. Genetic data strongly support a sister species relationship of the new species to M. macedonicus, the closest mainland taxon. Morphometric analyses provide satisfying criteria for diagnosis of this species relative to other Mediterranean species. The most obvious phenotypic characteristics are its long tail and the allometric gigantism and shape robustness of its cranial and dental characters compared to other Mediterranean mice. The molecular clock and the history of the murine settlement on Cyprus are congruent and suggest that the common ancestor of M. cypriacus and M. macedonicus arrived on Cyprus during the Middle Pleistocene by a founder event on natural raft. The remoteness of Cyprus through time has prevented introgression from the mainland gene pool, and favoured phenotypic adaptation to competition release, leading to the allopatric speciation of M. cypriacus.
Closterocerus oryzamyntor (Hymenoptera: Eulophidae: Entedoninae), a larval parasitoid of the rice hispa Dicladispa armigera in Bangladesh (Coleoptera: Chrysomelidae: Hispinae)
Authors: GUMOVSKY ALEX , POLASZEK ANDREW , MURPHY SEAN T. , RABBI M. F. , ZHU C.-D.
Published: March 2024

A new species of the genus Closterocerus (Hymenoptera: Eulophidae), Closterocerus oryzamyntor Gumovsky & Zhu sp. nov., is described based on morphological and molecular data. C. oryzamyntor is a larval endoparasitoid of a major pest of rice, Dicladispa armigera (Chrysomelidae: Hispinae). C. oryzamyntor is known so far only from Bangladesh, and only from this host. The species is characterized by the following morphological features: 1) deep sutures on the vertex of the male, connected to form a complete transvertexal suture in the female; 2) a comparatively long malar space, which is 0.3 times as long as the eye height, and 0.7 times as long as the breadth of the mouth; 3) predominantly pale femora, tibiae, tarsi and antennal scape; 4) the comparatively wide scape of the male, 2.6–2.7 times as long as broad; 5) the male pedicel, flagellum, coxae and gaster, which are all dark. Partial gene sequences of the 28S D2 ribosomal region were identical for all individuals sampled, but differed from two Closterocerus sequences on GenBank by 24 and 27 base pairs (about 6%). Both CytB and COI mitochondrial gene fragments demonstrated slight variation within the species, but no other eulophids have been sequenced for these genes, thus comparative data are lacking for these genes.
Belminus corredori, a new species of Bolboderini (Hemiptera: Reduviidae: Triatominae) from Santander, Colombia
Authors: GALVÃO CLEBER , ANGULO VICTOR M.
Published: March 2024

Belminus corredori, a new species of Bolboderini, is described on the basis of specimens collected in Puente Tierra, municipality of San Gil, Departament of Santander, Colombia. Specimens were found in well-built dwellings located approximately 1,810 meters of altitude in a region characterized by the presence of dry mountain forest.
Taxonomic note on Eupithecia cupressata Pearsall (Lepidoptera: Geometridae: Eupitheciini)
Authors: FERRIS CLIFFORD D.
Published: March 2024

The male of Eupithecia cupressata Pearsall is described, and illustrations of adults and genitalia of both sexes are provided.
Rediscovery and redescription of Hybocodon chilensis Hartlaub, 1905 (Cnidaria: Hydrozoa) from Comau Fiord, southern Chile
Authors: GALEA HORIA R.
Published: March 2024

Hybocodon chilensis Hartlaub, 1905, a poorly known species considered as of doubtful validity, is redescribed. Material examined was collected in Comau Fiord (Chile), situated a short distance from Calbuco, the original site where the type material was collected. Morphological features of living specimens of H. chilensis are fully described and illustrated, and data are provided on the cnidome. A table that compares polyp and medusa stages of species assigned to the genus Hybocodon L. Agassiz, 1862 is presented.  The systematic position of H. chilensis amongst the other members is discussed, and an identification key for the medusae is given.
A study of the genus Semnostola Diakonoff from China with the description of a new species (Lepidoptera: Tortricidae: Olethreutinae)
Authors: XU ZHANG , WANG SHUXIA
Published: March 2024

We report five species of Semnostola from China, including one new species, S. grandaedeaga, sp. nov., and one newly recorded species, S. triangulata Nasu & Kogi. The generic characters are amended based on the description of the new species. Photographs of the adults and the genitalia are provided. A key for the identification of the world species of Semnostola is given.
Two new species of the genus Friesea (Collembola: Neanuridae) from North-west China
Authors: GAO YAN , YIN WENYING
Published: March 2024

Two undescribed species of the genus Friesea were found from Guangtou Mountain, Chang’an city, Shaanxi Province, north-west China. They are described as new species in this paper. F. shaanxiensis sp. nov. has six anal spines and no furca. F. quadrispinensis sp. nov. has four anal spines.
A new species of Atractus Wagler, 1828 (Serpentes: Colubridae) from Eastern Amazonia, Brazil
Authors: PRUDENTE ANA L.D.C. , SANTOS-COSTA MARIA C. Dos
Published: March 2024

A new species of Atractus from the “Estação Científica Ferreira Penna”, Eastern Amazonia, Pará State, Brazil is described, and diagnosed by the following set of characters: 17-17-17 smooth dorsal scales without pits; 162 ventrals and 30 pairs of subcaudals in the single measurable male and 171 ventrals and 24 pairs of subcaudals in the single avaliable female; the three available specimens (two males and one female) has frontal wider than long; nasal contacting loreal, internasals, rostral, and the two first pairs of supralabials; loreal contacting internasal, and second and third supralabials; preocular absent; two postoculars; two light spots on the back of the head; wide-black median ventral band; and subcaudals totally black.
Ampeliscidae from the Brazilian coast. Record of Ampelisca burkey Barnard & Thomas, 1989 and descriptions of two new species of Ampelisca (Crustacea, Amphipoda)
Authors: VALÉRIO-BERARDO MARIA T. , WAKABARA YOKO
Published: March 2024

This study comprises the descripition of two new species of Ampelisca Costa, 1857, from Brazilian coast. Ampelisca flabellicaudata sp. nov. is characterized by head with antero-ventral and anterodorsal margins parallel, pereopod 7 carpus and propodus stout, subequal in length, urosomite 1 produced and pointed dorsally and uropod 3 with outer ramus rounded apically. Ampelisca moreirai sp. nov. is characterized by head with antero-ventral margin oblique, pereopod 7 merus posterodistal lobe enlarged to propodus, urosomite 1 dorsally produced into a sharpened upturned carina and uropod 3 lanceolate. Another species, Ampelisca burkey Barnard & Thomas, 1989 is herein first recorded from the Southwestern Atlantic Ocean.
Checklist of Monogenea parasites of freshwater and marine fishes, amphibians and reptiles from Mexico, Central America and Caribbean
Authors: KOHN ANNA , COHEN SIMONE C. , SALGADO-MALDONADO GUILLERMO
Published: March 2024

Two hundred and ten species from Mexico, 155 from the Caribbean (Bahamas, Bermuda, Cuba, the Dominican Republic, Guadeloupe, Jamaica, Puerto Rico and Trinidad) and 63 from Central America (Costa Rica, El Salvador, Guatemala, Nicaragua and Panama) with hosts and geographical distribution are listed in this contribution, bringing up to date the knowledge of Latin America monogenean fauna. A host parasite list with the monogenean species is presented.
Studies on the genus Onisimus Boeck, 1871 (Crustacea, Amphipoda, Uristidae) II. The barentsi and edwardsii groups
Authors: BERGE JØRGEN , VADER WIM , JOHNSEN JAN ROGER
Published: March 2024

Two taxonomical groups within the uristid genus Onisimus Boeck, 1871 are described: the barentsi- and the edwardsiigroup. The former currently consists of five species with O. krassini Gurjanova, 1951 considered as a junior synonym of O. barentsi (Stebbing, 1894). The edwardsii-group is considered as monotypic.
Thaumastaneis nigricans, a new species of a remarkable ant-mimetic Larginae (Hemiptera: Largidae) and the discovery of an ant-mimetic complex
Authors: DELLAPÉ PABLO MATÍAS , MELO MARÍA CECILIA
Published: March 2024

Thaumastaneis nigricans, a new species of Larginae from Bolivia, is described and compared with T. montandoni Kirkaldy & Edwards, the only other species known of the genus. This latter species is recorded from Paraguay for the first time, and its association with a Camponotus ant worker (Hymenoptera: Formicidae) and a Trigonidiidae cricket (Orthoptera) is mentioned. Several features of Thaumastaneis montandoni are illustrated via SEMs.
Convolutidae (Acoela) from Belize
Authors: ACHATZ JOHANNES G. , HOOGE MATTHEW D. , TYLER SETH
Published: March 2024

Convolutidae from shallow marine sediments, including six new species from Belize are described: Amphiscolops blumi sp. nov., Conaperta antonii sp. nov., Conaperta cirrata sp. nov., Convoluta lacrimosa sp. nov., Picola caribbea sp. nov., Polychoerus ebenhochi sp. nov.. A species from North Carolina previously identified as Polychoerus caudatus is herein described as new species, Polychoerus parvus sp. nov. The species Pseudohaplogonaria sutcliffei (Haploposthiidae) is reassigned to the genus Convoluta.
Historical record and supplementary description of Cymbasoma bullatum (A. Scott) (Copepoda: Monstrilloida) from the “Albatross” cruise in the Philippines
Authors: SUÁREZ-MORALES EDUARDO
Published: March 2024

A male monstrilloid copepod of the genus Cymbasoma Thompson, 1888, collected in 1908 by the U.S. Fisheries Steamer "Albatross" off Mindanao, Philippines, and deposited in the U.S. National Museum of Natural History, was originally identified and labeled as Monstrilla leucopsis (sic) Sars, 1921 by C. B. Wilson. Reexamination of this historical sample revealed that the specimen is in fact assignable to Cymbasoma bullatum (A. Scott, 1909), described from specimens collected in 1899 in the Moluccan Sea during the Dutch "Siboga" Expedition. My earlier redescription of this species, based on the incomplete, damaged specimens of the type lot, lacked taxonomically relevant details and is supplemented herein. This species can be distinguished from its congeners by a combination of characters including the body proportions, armature of the antennules, presence of an anterior rostral protuberance, and structure of the genital lappets. New characters for distinguishing males of Cymbasoma species are evaluated. A relatively recent (1981) record of C. bullatum in Japan was evaluated in the light of these new data. Several differences in, e.g., antennulary armature, proportions of fifth pedigerous and anal somites, and morphology of the genital lappets, suggest that the Japanese specimens represent an undescribed taxon.
New data on morphology and natural history of Deltamys kempi Thomas, 1919 (Cricetidae, Sigmodontinae) from central-eastern Argentina
Authors: TETA PABLO , CUETO GERARDO , SUÁREZ OLGA
Published: March 2024

We provided new data on morphology and natural history of the rare sigmodontine rodent Deltamys kempi. Field work was conducted in Reserva Costanera Sur, Buenos Aires, central-eastern Argentina during two consecutive years. The glans penis of D. kempi is short and stocky and sub-cylindrical in appearance; the stomach is unilocular-hemiglandular; the baculum has a well developed cartilaginous portion, with two lateral digits and a central one; gall bladder is present. We also describe for the first time the soft palate and the manus and pes morphology. Soft palate, stomach, glans penis, manus and pes morphology of Deltamys is similar to Akodon, its hypothesized sister taxon. D. kempi was more frequently captured in relatively pure stands of the tall grass Cortaderia selloana. According to the available records in Argentina, D. kempi occupies preferably grassy marshes and dense gramineous patches in gallery forest. Reproductive season seems to start at the late winter-early spring and to last until the end of summer-early autumn. Stomach contents of four individuals had mainly insects and insect larvae. Ectoparasites found in D. kempi included the Acari Androlaelaps fahrenholzi, A. aff. A. rotundus and Laelaps paulistanensis, and the Siphonaptera Polygenis sp.
Catalogue of Blattaria (Insecta) from Brazil
Authors: PELLENS ROSELI , GRANDCOLAS PHILIPPE
Published: March 2024

Este artigo é um catálago atualizado das espécies de baratas registradas no Brasil. Ele traz uma lista de espécies, sua distribuição nos diferentes estados do país, a instituição na qual os tipos estão depositados e uma lista de referências atualizada. Os resultados indicam 644 (mais 3 incertae sedis) espécies, pertencentes a 6 famílias, 18 subfamílias e 107 gêneros atualmente reconhecidos. Os tipos destas espécies estão distribuídos em pelo menos 29 instituições. O estudo da distribuição das espécies nos diferentes estados mostra que muitas podem ser encontradas em todo o país, ainda que para 7,7 % das espécies apenas sabe-se que elas ocorrem no Brasil. Os estados com maior número de ocorrências foram Rio de Janeiro (169), Pará (132) e Amazonas (120) e os mais pobres foram os estados do Nordeste, onde a Caatinga e o Cerrado são os ecossistemas dominantes. Entretanto, o número de espécies parece fortemente associado com o esforço de pesquisa. A curva cumulativa de espécies indica um número marcadamente crescente de espécies descritas ao longo do tempo, a qual ainda está ascendente, sem tendência de estabilização. Esta informação, juntamente com os outros resultados, indica que a fauna de baratas do Brasil ainda é muito pouco conhecida e sugere que o número total de espécies no país pode ser pelo menos cinco ou seis vezes superior.