bluuebunny/crossref_metadata_2025 huggingface dataset:
Extracellular vesicles in the treatment and prevention of osteoarthritis: can horses help us translate this therapy to humans?
Authors: O’Brien Thomas J , Hollinshead Fiona , Goodrich Laurie R
Published: April 2023

Osteoarthritis (OA) is a common joint disease affecting humans and horses, resulting in significant morbidity, financial expense, and loss of athletic use. While the pathogenesis is incompletely understood, inflammation is considered crucial in the development and progression of the disease. Mesenchymal stromal cells (MSCs) have received increasing scientific attention for their anti-inflammatory, immunomodulatory, and pro-regenerative effects. However, there are concerns about their ability to become a commercially available therapeutic. Extracellular vesicles (EVs) are now recognized to play a crucial role in the therapeutic efficacy observed with MSCs and offer a potentially novel cell-free therapeutic that may negate many of the concerns with MSCs. There is evidence that EVs have profound anti-inflammatory, immunomodulatory, and pro-regenerative effects equal to or greater than the MSCs they are derived from in the treatment of OA. Most of these studies are in small animal models, limiting the translation of these results to humans. However, highly translational animal models are crucial for further understanding the efficacy of potential therapeutics and for close comparisons with humans. For this reason, the horse, which experiences the same gravitational impacts on joints similar to people, is a highly relevant large animal species for testing. The equine species has well-designed and validated OA models, and additionally, therapies can be further tested in naturally occurring OA to validate preclinical model testing. Therefore, the horse is a highly suitable model to increase our knowledge of the therapeutic potential of EVs.
The Effect of Ramadan Intermittent Fasting on Food Intake, Anthropometric Indices, and Metabolic Biomarkers among Pre-and Post-menopausal Women: A Cross-Sectional Study
Authors: Alzunaidy Nada , Al-Khalifa Abdulrahman Saleh , Alhussain Maha Hussain , Mohammed Ahmed Mohammed Awad alkareem , Alfheeaid Hani A. , Faris MoezAlIslam E. , Althwab Sami A.
Published: April 2023

By shifting eating hours from daytime to nighttime, Ramadan intermittent fasting (RIF) illustrates how religious beliefs influence human dietary behavior and subsequent anthropometric and metabolic measures. This study aimed to investigate socioeconomic characteristics and examine how observing RIF affects dietary intake, anthropometric indices, and metabolic markers in healthy premenopausal (PRE-M) and post-menopausal (POST-M) Saudi women. Before starting the study, the authors hypothesized that the RIF improves some nutritional aspects and health in respondents, but not after breaking the fast.. The study includes 62 women (31 PRE-M, 21-43 years, and 31 POST-M, 44-68 years). A structured questionnaire was used to collect socioeconomic data. Physical activity, anthropometric, dietary, and biochemical assessments were undertaken before RIF and at the end of the third week of Ramadan fasting month. Socioeconomic data varied among respondents. Observing RIF was associated with significantly (at either p ≤ 0.01 or p ≤ 0.05) lower intake of calories, macronutrients, minerals (except for Na), and vitamins than before RIF for both groups. In terms of body mass index (BMI), and waist-to-height ratio (WHtR) for PRE-M, the percentage of overweight decreased significantly (p≤0.01) while obesity remained unchanged. In contrast, for POST-M, the percentage of overweight increased significantly (p≤0.05), but obesity decreased after RIF. Both groups' waist-to-hip ratio (WHR), body fat (BF), and fat mass (FM) decreased after RIF. High-density lipoprotein cholesterol (HDL-C), fasting blood glucose (FBG), triglycerides (TG), and blood pressure (SBP, DBP) were generally maintained at acceptable normal levels in most responders before and after RIF. However, low-density lipoprotein cholesterol (LDL-C) was significantly decreased during RIF than before, especially for POST-M. Age, occupation, and monthly income were the most important factors influencing women’s nutritional status and body fat. In conclusion, observing RIF by PRE- and POST-M Saudi women was associated with significant improvements in variable health indicators, with a few exceptions, particularly POST-M, and may help lower risk factors for chronic diseases.
Variation in Relative Abundance of Small Mammal species Caught in Two Different Ecosystems And Implicated in the Spread of Emerging Pathogens, in Mali
Authors: Koné Abdoulaye Kassoum , Diatta Georges , Niare Doumbo Safiatou , Ag Atteynine Solimane , Coulibaly Maïmouna , Diarra Adama Zan , Sagara Issaka , Djimdé Abdoulaye , Doumbo Ogobara , Thera Mahamadou Ali
Published: April 2023

Small rodents and insectivores are potential reservoirs of many pathogens transmissible to humans such as bacteria, parasites and viruses responsible for epidemics in sub-Saharan Africa, particularly in West Africa. Few studies on small mammal species in the Kolikoro and Sikasso regions are available, hence the interest in investigating the different species of small rodents and insectivores, and their role in the transmission of pathogens to humans. The study aims to identify commensal small mammal species circulating in Faladjè and Bougouni areas, and likely to represent major risks of epidemic disease emergence. Sessions of trapping were carried out in December 2016 in Faladjè and Bougouni with wire mesh traps type “Besançon tous services” (BTS) baited with peanut butter and/or onion. All animals captured were identified morphologically. Out of 123 small rodents and insectivores captured in 674 trap nights, 75 (60.97%) were from Faladjè and 48 (39.02%) from Bougouni, Of these, six species of small rodents belong to the family Muridae (Mastomys erythroleucus, Mastomys natalensis, Rattus rattus, Praomys daltoni, Gerbilliscus gambianus, Taterillus gracilis) and two species of insectivores associated with the genus Crocidura spp. belong to the family Soricidae and Erinaceidae (Crocidura cf olivieri and Atelerix cf albiventris) respectively. There is low specific diversity within these two stands, but the variation in relative abundance is significant (binomial test, p = 0.018 ˂ 0.05) between the Faladjè and Bougouni stands of small mammals. Mastomys erythroleucus was the most dominant species (57.33%, 43/75) in the Faladjè settlement and R. rattus dominated (37.5%,18/48) that of Bougouni. These two species of small mammals are potentially involved in the transmission of bacteria, parasites and pathogenic viruses to humans.
Ameliorative Effect of Chitosan-Propolis Nanoparticles on the Estradiol Valerate -Induced PCOS in Rat
Authors: Hosseini Seyede Fatemeh , Khodaei Forouzan , Hasansagha Zeynab , Khosravizadeh Hamidreza , Abdollahi Mostafa , Azaryan Ehsaneh
Published: April 2023

Background: Endocrine conditions that impact women define polycystic ovary syndrome. Previous studies have demonstrated a connection between PCOS and insulin intolerance, oxidative stress, and immune system dysfunction. Additionally, some reports have indicated that propolis has antioxidant properties and that chitosan nanoparticles have beneficial effects on the reproductive system. The goal of the present study is to compare metformin (Met) to chitosan-propolis nanoparticles and explain how they protect against a rat PCOS model caused by estradiol valerate (EV). (as a control treatment).

Methods: In order to cause PCOS in rodents, a single subcutaneous injection of estradiol valerate was used, followed by a 42-day oral administration of 500 mg/kg of chitosan-propolis nanoparticles. Four sets of rats were created: the control, PCOS, metformin (PCOS and 150 mg/kg metformin), and chitosan-propolis nanoparticle (PCOS and 500 mg/kg chitosan-propolis nanoparticle) groups. The histopathological examination of the ovaries and measurement of serum ferctors were performed on all of the animals. Estradiol valerate caused PCOS, but chitosan-propolis nanoparticle therapy reversed it.

Results: After chitosan-propolis nanoparticle intervention, the body weight and ovarian morphology had improved, and the serum biochemical parameters, including esretogen, progestron, vitamin D, calcium, and the insulin resistance index, had been corrected. These EV-induced changes include decreased SOD activity, elevated MDA levels, and evidence that oxidative stress was increased by EV when chitosan-propolis nanoparticle/Met were administered for 42 straight days. Additionally, certain relative mRNA transcripts, including those for the MCP, IL18, and CRP genes, were markedly upregulated in EV-treated animals. These findings unequivocally demonstrate the beneficial effects of chitosan-propolis nanoparticles/Met in inflammatory disorders.

Conclustion: Together, the study's end findings, which are presented here, are consistent with the hypothesis that chitosan-propolis nanoparticle/Met offered protective activity against the harmful effects of EV. Although ameliorative effects may have been implicated, the primary pathway or pathways still need to be clarified.
Measuring the Awareness Levels of Alcohol and Substance Addicted Individuals and Tertiary Prevention Standards: Development of Uskudar Result Awareness and Harm Perception Scales
Authors: Tarhan Nevzat , Demirsoy Çiğdem , Tutgun Ünal Aylin
Published: April 2023

Alcohol and substance addiction is a type of brain disease that damages many areas of life of the individual and has psychological components. Since questioning alcohol use alone is not sufficient in the diagnostic evaluation process, self-awareness and the individual's long-term psychological well-being are important in the rehabilitation process. Since investigating alcohol use alone is not sufficient in the diagnostic evaluation process, self-awareness and the individual’s long-term psychological well-being are important in the rehabilitation process. Primary prevention is used to prevent disease in healthy people, and secondary prevention is used for early diagnosis to people at risk. Tertiary prevention is important to prevent recurrence of the disease in the treated person. In addiction, which is a chronic problem, a need has emerged for tertiary prevention, that is, rehabilitation standards. If people are uncertain about the harm perception and the natural result of their behavior, they easily slip into the substance. Therefore, as a positive psychotherapy technique, harm perception and result awareness levels should be clarified. For this reason, scales were developed. The inclusion of new psychology perspectives and therapy techniques, such as positive psychology, in the treatment process requires setting new standards. In this study, it was aimed to develop result awareness and harm perception scales to determine the awareness levels and rehabilitation standards of alcohol and substance addicted individuals, and to compare awareness in normal and addicted groups. The study group consisted of 1134 participants, 41 of whom were addicts. Among the two scales developed in the study, the Uskudar Result Awareness Scale (USRAS) consisting of 25 items and 6 factor, explained 58.4% of the total variance. The Uskudar Harm Perception Scale (USHPS), consisting of 36 items and 10 factors, explained 56.3% of the total variance. Confirmatory factor analysis of the two scales resulted in acceptable goodness-of-fit values. (X2/df<3; RMSEA<.08; NFI>.90; NNFI>.95; CFI>.95; GFI>.90; AGFI>.85). In the comparisons made, the result awareness of the normal group was moderate (X=3,81); whereas the addicted group had a low result awareness (X=3,20); The effect size of the difference between the two groups was found to be high (d=1,45; >0,8). In the other measure, the harm perception of the normal group was found in the low-risk group (X=3,78); the harm perception of the addicted group was found in the moderate-risk group (X=3,43). According to Cohen d calculations, the effect size of the difference between the two groups is high (d=1,43; >0,8). It has been concluded that the two scales that emerged in the research are valid and safe, can be included in the rehabilitation studies and the creation of self-awareness, and their effectiveness should be tested.
Advanced Proteomic and Bioinformatic Tools for Predictive Analysis of Allergens in Novel Foods
Authors: Pedrouso María Dolores , Lorenzo José M. , Alché Juan de Dios , Moreira Ramón , Franco Daniel
Published: April 2023

In recent years, novel food is becoming an emerging trend increasingly more demanding in developed countries. Food proteins from vegetables (pulses, legumes, cereals), fungi, bacteria and insects are being researched to introduce them in meat alternatives, beverages, baked products and others. One of the most complex challenges for introducing novel foods on the market is to assure food safety. New alimentary scenarios drive the detection of novel allergens that need to be identified and quantified with the aim of appropriate labelling. Allergenic reactions are mostly caused by proteins of great abundance in foods, most frequently of small molecular mass, glycosylated, water-soluble and with high stability to proteolysis. The most relevant plant and animal food allergens such as lipid transfer proteins, profilins, seed storage proteins, lactoglobulins, caseins, tropomyosins and parvalbumins from fruits, vegetables, nuts, milk, eggs, shellfish, and fish have been investigated. New methods for massive screening in the search of potential allergens must be developed particularly concerning protein databases and other online tools. Moreover, several bioinformatic tools based on sequence alignment, motif identification or 3-D structure predictions should be implemented as well. Finally, targeted proteomics will become a powerful technology for the quantification of these hazardous proteins. The ultimate objective is to build an effective and resilient surveillance network with this cutting-edge technology.
A Strong 2023/24 El Niño Is Staged by Tropical Pacific Warm Water Buildup
Authors: Lian Tao , Wang Jie , Chen Dake , Liu Ting , Wang Dazhi
Published: April 2023

The upper ocean heat content in the equatorial Pacific usually serves as a primary precursor for an upcoming El Niño, while the strong atmospheric perturbations such as westerly wind burst and easterly wind surge sometimes play a decisive role in determining the final intensity of the event. The tropical Pacific Ocean has just experienced a rare 3-year La Niña, which accumulated a huge amount of warm water in the western basin by the winter of 2022. Using a state-of-the-art climate prediction system, here we show that the restored warm water is sufficient to boost a strong El Niño toward the end of 2023, and that an extreme event could take place if a few sizable westerly wind bursts would occur in spring and early summer. This prediction is not sensitive to initial errors within the tropical Pacific, but may be subject to some uncertainties brought about by influences from elsewhere.
Effects of Twins Therapy on Egocentric and Allocentric Neglect in Stroke Patients
Authors: Jang Woo-Hyuk , Hwang Hyeong- Min , Kim Jae-Yeop
Published: April 2023

Abstract: (1) Background: existing treatment methods for neglect are concentrated on egocentric neglect and lead to various problems, such as cost/space constraints and portability. Therefore, this study seeks to determine how treatment (a.k.a., Twins Therapy, TT) can improve an existing problem in relation to neglect in stroke patients; (2) Method: The research design was a pre-post test control group design and both groups maintained existing rehabilitation treatment and added TT intervention only to the experimental group. TT intervention was conducted for a total of 20 sessions (1 session 30 min/day, 5 days/week for 4 weeks); (3) Result: as a result of comparison be-fore and after the TT intervention, there was no significant difference in MFT and MBI items (p>.05). However, the score and execution time of the Apple Cancellation Test showed significant reduction only in the experimental group (p<.05); (4) Conclusion: as a result of the study, TT im-proved not only egocentric neglect, but also allocentric neglect symptoms in stroke patients
Unraveling the Hidden Impact of Tumor Microenvironment: Insights into Novel Therapeutic Strategies for Oncology in Tanzania: Integrated Review
Authors: Mvandal Samson Peter , Mlonganile Wende
Published: April 2023

The tumor microenvironment (TME) plays a critical role in cancer progression and treatment outcomes. Despite advances in cancer research, many therapeutic strategies have failed to provide the desired clinical outcomes. In this integrated review, aimed to explore the role of TME in cancer biology and develop novel therapeutic strategies that target not only cancer cells but also the surrounding microenvironment. Study conducted a comprehensive literature search using PubMed, Embase, and Web of Science databases for articles published between 2016 and 2022. Inclusion of articles that discussed the impact of TME on cancer development and progression, as well as articles that proposed novel therapeutic strategies targeting the TME. The analysis of the literature revealed that the TME plays a crucial role in cancer development and progression by promoting cancer cell survival, angiogenesis, invasion, and metastasis, and by interfering with the efficacy of cancer therapies. The TME is composed of a complex network of non-cancerous cells, extracellular matrix components, and signaling molecules that interact with cancer cells. Several novel therapeutic strategies have been proposed based on the modulation of TME components. One of the most promising approaches is the use of immunotherapy, which aims to enhance the immune system's ability to recognize and attack cancer cells. Immunotherapy drugs such as checkpoint inhibitors, chimeric antigen receptor (CAR) T cells, and immune-stimulatory monoclonal antibodies have been approved for the treatment of different cancer types. These approaches have shown promising results in preclinical studies and clinical trials. The TME plays a critical role in cancer development and progression, and targeting its components represents a promising avenue for cancer therapy. Novel therapeutic strategies such as immunotherapy, extracellular matrix-targeting drugs, and nanoparticle-based therapies have shown promising results in preclinical studies and clinical trials. However, further research is needed to identify the most effective strategies and to overcome the challenges associated with TME targeting.
High Imperceptible Data Hiding Method for AMBTC Compressed Images Based on Combination Theory
Authors: Anggriani Kurnia , Chiou Shu-Fen , Wu Nan-I , Hwang Min-Shiang
Published: April 2023

The rapid development of digital multimedia has resulted in a massive storm of large-scale data. The data compression method reduces data size and lowers transmission costs. As a result, data-hiding research in the compression domain poses significant challenges to researchers. This paper proposes a highly imperceptible data-hiding scheme for a compressed image of Absolute Moment Block Truncation Coding (AMBTC). The combination theory is implemented to ensure the high imperceptibility of the modified compressed images. By only modifying one pixel in a block to embed secret bits, the experimental results show that the proposed method achieved high imperceptibility and high hiding capacity.
Inspiring the Future: The Influence of Historical and Contemporary Role Models on Women's Leadership Paths
Authors: Al Naqbi Shamma
Published: April 2023

Women's leadership continues to be a critical issue in today's society. Women face significant challenges in leadership, including limited representation in high-level positions and persistent gender-based discrimination. Many factors, including personal experiences, education, work experiences, and the influence of role models, influence women's leadership paths. This study explores how historical and contemporary role models help guide women's leadership choices. Specifically, we seek to understand the role of historical and contemporary role models in shaping women's perceptions of leadership and influencing their career aspirations.The study uses a qualitative research design to explore the experiences of women leaders in different industries. The participants were selected using purposive sampling, and data were collected through semi-structured interviews. Thematic analysis was used to identify patterns in the data, and the results were presented using descriptive statistics and qualitative data analysis.The study findings reveal that historical and contemporary role models significantly shape women's perceptions of leadership and influence their career aspirations. Women who have had access to role models in their personal lives or through media exposure are more confident in their ability to lead. They are more likely to pursue leadership positions. Historical role models provide women with tangible examples of what is possible regardingwomen's leadership. Studying role models from diverse backgrounds is essential in inspiring women from diverse backgrounds to pursue leadership roles.The study findings have significant implications for women's leadership development. They suggest efforts to increase the representation of women in leadership positions should focus on providing access to diverse role models. Additionally, the study highlights the importance of media representation of women leaders, as exposure to role models through media can help overcome barriers to access to role models in personal and professional networks.In conclusion, the study provides important insights into the influence of historical and contemporary role models on women's leadership paths. The study underscores the importance of role models in inspiring and guiding women's leadership journeys and the need for diverse and inclusive representation of women leaders in media and personal and professional networks. The findings provide practical recommendations for women's leadership development initiatives and future research.
Management of Dry Eye Disease in Asia: A Review
Authors: Kawahara Atsushi
Published: April 2023

Dry eye disease (DED) is a multifactorial disorder in which tear fluid homeostasis is lost, resulting in increased tear film osmolarity and ocular surface irritation. In Asia, the short tear film breakup time type-DED is common, and stabilization of the tear film is the first goal of treatment. Treatment of DED begins with eye drops. Until now, artificial tears and steroid eye drops have been the main treatment for DED. However, artificial tears require frequent administration of eye drops and thus pose adherence problems, while steroids have problems with side effects (cataracts, increased intraocular pressure). This review evaluates the new generation of DED therapies in Asia based on what is known about them and demonstrates that they are more effective for DED than traditional therapies such as artificial tears and steroids. Based on these considerations, it is proposed that the optimal treatment for DED in Asia is the initial application of mucin secretion enhancing eye drops (long-acting diquafosol) and oral supplements, and if additional treatment is needed, cyclosporine eye drops and the adjunctive therapies presented in this review are added.
From Bioclimatic Envelopes to Machine Learning: A Journey Through the History, Present, and Future of Species Distribution Modeling With Practical Tips for Use and Notes to Bryophytes
Authors: Číhal Lukáš
Published: April 2023

Species distribution modeling (SDM) has come a long way since its inception. Starting as simple bioclimatic envelope models based on expert knowledge, species distribution models (SDMs) have evolved into complex and sophisticated models that incorporate multiple sources of data and machine learning algorithms. Today, SDMs play a crucial role in addressing pressing conservation and management issues, including the impacts of climate change on species ranges and the as-sessment of species vulnerability to extinction. In this article, we will embark on a journey through the history, present, and future of SDM, exploring its evolution from bioclimatic envelopes to machine learning. We will also provide practical tips on how to use SDMs effectively and discuss the exciting future developments in this field. Whether you are a seasoned SDM expert or new to this field, this article will provide valuable insights into the exciting world of SDM. By exploring the rich history and current state of the field, we hope to shed light on the tremendous potential of SDM for improving our understanding of the distribution of species in a changing world.
Better alone? The impact of living arrangements on mortality of Costa Rican older adults
Authors: Vazquez-Castillo Paola
Published: April 2023

Previous research has shown differentiated effects of living arrangement types on mortality. However, little is known about this phenomenon in Latin America and its multigenerational households. This study measures the relationship between older adults’ living arrangement types and subsequent mortality. Gompertz event history models were performed to estimate mortality differences across living arrangements. We used the Costa Rica Longevity and Aging Study (CRELES) pre-1945 cohort in the 2005, 2007, and 2009 waves. The results show that older adults who live with a partner have the highest survival rates among the categories tested. When controlling for sex and age in the model, the effect of living alone is not different from partnered living. When controlling for socioeconomic and health factors as well, older adults living with their children or others show an increased risk of death by at least 40% (p-value<0.05). The study demonstrates an association between living arrangements and older adult mortality in Costa Rica. Results show that the highest survival chances rely on being partnered and suggest that support exchanges with other family members are not equally effective. Including this variable type in mortality studies is crucial to better understanding how household conditions relate to health and mortality outcomes.
Multiple representations (MR) based instructional approach in support of physics identity and physics teachers' identity development: Design considerations
Authors: Munfaridah Nuril , Goedhart Martin
Published: April 2023

In this paper, we describe the intervention and the context of implementation of a multiple representations (MR)-based instructional approach as a classroom practice in an first-year thermodynamics course for preservice physics teachers at an Indonesian university. We argue that the implementation of this approach will contribute to the enhancement of students’ conceptual understanding and problem-solving skills. By enhancing those two aspects, we intend to contribute to their development of physics identity and physics teacher identity. We illustrate how this MR approach is applied in the classroom and describe how the relationship between the aspects of this approach interacts with physics identity and physics teacher identity. During lessons the teacher used real-life examples and students were encouraged to use different representations when they solved problems in small groups. The students realized that learning physics could involve many representations and might increase their interest to physics. However, we found some situations that did not match our expectations. For instance, most of the students were more interested when the problems were in the form of mathematical representation. In addition, we found that some students were inactive in the class. Therefore, it is necessary to think as educators about how to provide a positive learning experience to stimulate the development of student's identity. This work exemplifies how physics educators can stimulate physics and physics teacher identity formation in their physics courses as a preparation for future physics teachers.
Implementation of STEM Project-Based Learning (PjBL) student worksheet through the “otok-otok” boat game on engineering thinking skills
Authors: Angelina Oktania Putri , Handayani Rif’ati Dina , Maryani Maryani
Published: April 2023

Physics learning is a science learning branch that explores and explains natural phenomena. Nevertheless, students still consider physics learning difficult because it has several abstract concepts and mathematics. Also, physics learning is rarely conducted in terms of higher-order thinking processes. This study aims to investigate students’ engineering thinking skills using STEM PjBL on the “Otok-Otok” boat game. This type of research is qualitative research with a single case study method. Data were gathered through interviews, observation, and documentation. The data obtained were analyzed using a content analysis method. The results showed that the students’ engineering thinking skills were excellent. STEM-PJBL directs students in structuring the engineering thinking skills. Students can solve problems in a structured way, from identifying issues to analyzing alternative solutions to problems. This study is expected as essential information to implement STEM-PJBL for teachers in their physics learning.
Investigation of facilities and students’ readiness in supporting implementation of nodemcu-based bifocal modeling physics practicum
Authors: Sunardi Sunardi , Suhandi Andi , Darmawan Deni , Muslim Muslim
Published: April 2023

This research was carried out to get overviews which deal with facilities and students’ readiness to support the implementation of NodeMCU-based bifocal modeling physics practicum. The location of this research was in a senior high school in Bandung District, Indonesia. The subjects of this research were physics teachers and students of that school enrolled in 2020/ 2021. This research was a case study, the data of which were collected through interviews, observation, and questionnaire. Interviews and observation were focused to gather information due to the school facilities supporting the implementation of NodeMCU-based bifocal modeling physics practicum. Questionnaire was used to reveal the readiness of students in accepting implementation of NodeMCU-based bifocal modeling physics practicum. Based on the data analysis, it was found that the school facilities meet technical specifications of NodeMCU, so the implementation of NodeMCU-based bifocal modeling physics practicum may be potentially supported by the school facilities; most students also own facilities (smartphones and laptops/ computers) which may be potentially utilized as output peripherals for displaying visualized physics phenomena and simulated physics data from a tool of NodeMCU-based bifocal modeling physics practicum; students are willing to accept the implementation of NodeMCU-based bifocal modeling physics practicum in physics learning, because it can improve the quality of physics learning, improve the motivation of students to learn physics, and help students to easily understand physics concepts.
Chaos to fractals
Authors: Pulinchery Prasanth , Pothyiodath Nishanth , Murkoth Udayanandan Kandoth
Published: April 2023

In undergraduate classrooms, while teaching chaos and fractals, it is taught as if there is no relation between these two. By using some non linear oscillators we demonstrate that there is a connection between chaos and fractals. By plotting the phase space diagrams of four nonlinear oscillators and using box counting method of finding the fractal dimension we established the chaotic nature of the nonlinear oscillators. The awareness that all chaotic systems are good fractals will add more insights to the concept of chaotic systems.
The assessment of student numeracy ability for sustainable learning in Indonesia: A study in a high school science class
Authors: Listianingrum Serly Anggraini , Istiyono Edi , Zakwandi Rizki , Chusni Muhammad Minan
Published: April 2023

This study aimed to measure student numeracy ability within the context of physics on the kinetic theory of gases. This study employed a quantitative method with descriptive and parametric statistics analysis. Sixty-two sample students were measured for numeracy ability. The research instrument applied was the ten numeration questions that had been tested empirically. The research indicates that the student cognitive level positively influences numeracy ability with an effect size value of 0.682 and an Adj. R2 value of 0.676. Furthermore, gender-related analysis proves that there is no gap in the numeracy ability with an effect size value of 0.030 and Adj. R2 is 0.014. This study has implications for designing physics learning that develops numeracy ability, especially in determining learning designs that accommodate cognition level and gender.
Developing Mobile Learning of Physics (MOBLEP) with android-based problem-based learning approach to improve students’ learning independence
Authors: Fathurohman Apit , Murniati Murniati , Sukemi Sukemi , Susiloningsih Esti , Erni Erni , Kurdiati Lintang Auliya , Samsuryadi Samsuryadi
Published: April 2023

This development research aims to produce Mobile Learning of Physics (Moblep) by applying Android-based Problem Based Learning Approach to Increase Student Learning Independence which is valid and practical. The development model used is the Rowntree model modified with Tessmer's formative evaluation method. The tessmer's formative evaluation stages in this study include self-evaluation, expert review, one-to-one, and small group. At the expert review stage, data were collected through interviews, expert tests, and questionnaires using nine material experts, nine design experts, and eleven language experts. The one-to-one stage and the small group stage were carried out at SMA Negeri 1 Suak Tapeh. The results showed that the Mobile Learning of Physics (Moblep) with the Android-based Problem-Based Learning Approach that was developed, based on the results of the expert review, obtained a total percentage score of 94.73% from the validator and was included in the "very valid" category. Based on the results of the student response questionnaire at the one-to-one evaluation stage, the average percentage was 83.5%, and at the small group stage, the average percentage was 95.2%, so this Moblep was included in the "very practical" category.The implication of this research is that the results of this study can be applied as reference material and considered as additional references for further research.
Assessment of pre-service physics teachers’ conceptual understanding in electricity and magnetism
Authors: Mihret Zemenu , Alemu Mekbib , Assefa Shimeles
Published: April 2023

This study focused on an assessment of pre-service physics teachers’ conceptual understanding of physics in the domain of electricity and magnetism concepts. The study employed a descriptive survey method of research. The study sample consisted of 100 pre-service physics teachers from five teacher education colleges during the academic year 2021/21. The study used preliminary data from a PhD dissertation that was gathered by administering a conceptual understanding test on electricity and magnetism, which contained 32 items adapted from standardized tests. The data were analyzed using descriptive statistics, one sample t-tests, independent samples t-tests, and one-way ANOVA. The results of the one sample t-test showed that the conceptual understanding test scores for electricity and magnetism were considerably below 50 and 70 which are the national standard pass mark points and the baseline for certification of competency to the teaching profession, respectively. ANOVA analysis revealed that there was a statistically significant mean difference among the pre-service physics teachers in the colleges. The post hoc test analysis showed that there was a statistically significant mean difference between pre-service teachers from two colleges. The independent samples t-test revealed that there was statistically significant mean difference between test scores of males and females in favor of male pre-service physics teachers. In addition, the participation of female candidates was too low compared to their male counterparts. In conclusion, the achievement of pre-service physics teachers was below the expected values; differences among colleges were detected; and there was an achievement and participation imbalance in relation to gender, though consecutive measures were taken. Based on the conclusions, recommendations are given that could be applicable.
Implementation of Law Number 26 of 2007 concerning Spatial Planning for Green Open Space in the Form of Construction of Public Park Facilities in Krembung District, Sidoarjo Regency
Authors: Maarif Zaenal
Published: April 2023

This study aims to determine the imlpemntation of law Number 26 to 2007 concerning Spatial Planning in Krembung District, Sidoarjo Regency. Furthermore, it is analyzed regarding its application in the field by means of interviews to find by means of conformity with existing laws.This thesis research uses law number 26 year 2007. In empirical research, the auther will use the sociological juridical method with research carried out derectly in the field, using the metehod of seeing the appropriateness of the application of the law and supported by interview activites.The result of policy research on the implimentation of law number 26 of 2007 are still focused on road procurement. From the result of interviews with villige officials, the community hopes to have a of a garden in krembung District. The problem experiended in park procurement are the lack of budget, the future trem for constraction and the lacj of socialization on the importance of green open space for the community.
Achieving Goals in Effectiveness of the Two-Wheel Vehicle Tax Clearance Program at the Joint Office of SAMSAT Krian, Sidoarjo Regency
Authors: Nurainiyah Nurainiyah , Choiriyah Ilmi Usrotin
Published: April 2023

The results of the study were not achieved in achieving the goals of the bleaching program. Clarity of strategy in achieving goals has been carried out by the office with the SAMSAT but not optimally so that the goal has not been achieved, the availability of work facilities and infrastructure in the SAMSAT office is well-available and effective and efficient implementation of the whitening program has been implemented. Program, Bleaching, Motor Vehicle Tax The whitening program is the abolition of motor vehicle tax administration sanctions in the form of motor vehicle tax fines issued by the governor, which aims to increase public compliance and awareness in paying motor vehicle taxes. The whitening program has been implemented at the Joint Office of the Krian Samsat, Sidoarjo Regency, but there are still taxpayers who are in arrears in paying the two-wheeled motorized vehicle tax so that the whitening program has not yet reached the specified target. The research method uses descriptive qualitative. Data were obtained through interviews, observation and documentation. The results of the study were not achieved in achieving the goals of the bleaching program. clarity of goals to be achieved is clear. Clarity of strategy in achieving goals has been carried out by the office with the SAMSAT but not optimally so that the goal has not been achieved, the availability of work facilities and infrastructure in the SAMSAT office is well available and, effective and efficient implementation of the whitening program has been implemented.
The Influence of Accounting Student Perceptions About Taxes, Tax Brevet and Motivation on Career Interest in Taxation
Authors: Akbar Wahyu Al , Ernandi Herman
Published: April 2023

The purpose of this study was to examine and obtain evidence regarding (1) accounting students' perceptions of taxation on interest in a career in taxation, (2) tax brevet on interest in a career in taxation, (3) motivation for interest in a career in taxation. This research is a type of quantitative research with hypothesis testing. The sample used in this study was 85 accounting students at Muhammadiyah Sidoarjo University consisting of semesters 6, 8 and 10. The analytical tools used were multiple linear regression test, correlation coefficient (R), coefficient of determination (R²), t test, and test. F using the SPSS version 18.0 for windows program. This primary data was obtained from a questionnaire whose measurement was using a Likert scale which was tested for validity and reliability. The results of the validity and reliability test showed that the data were valid and reliable. The results of the t-test indicate that the student's perception of taxes, tax brevet, and motivation partially affect the interest in a career in taxation.
The Influence of Board of Commissioners Size, Company Size, and Profitability on Corporate Social Responsibility (CSR) Disclosures (Study on Pharmaceutical Companies Listed on the Indonesia Stock Exchange 2016-2019)
Authors: Dharmawan Ridho Dwiki , Hermawan Sigit
Published: April 2023

This study aims to determine the effect of Board of Commissioners Size, Company Size, and Profitability on Corporate Social Responsibility (CSR) Disclosures (Study on Pharmaceutical Companies Listed on the Indonesia Stock Exchange 2016-2019). The sampling method used is purposive sampling method. The number of companies that were sampled in this study were 8 Pharmaceutical Companies Listed on the IDX for the 2016-2019 period. The data used is secondary data. The data analysis method used in this research is Multiple Linear Regression. The results of this study indicate that the size of the Board of Commissioners has an effect on Corporate Social Responsibility in pharmaceutical companies listed on the IDX for the 2016-2019 period. Company size has an effect on Corporate Social Responsibility in pharmaceutical companies listed on the IDX for the 2016-2019 period. Profitability has an effect on Corporate Social Responsibility in pharmaceutical companies listed on the IDX for the 2016-2019 period.
Implementing Pancasila Economic System through BUMDes: A Legal Analysis on Desa Empowerment and Indonesia's Legal Framework
Authors: Jayantara Made , Kurniawan I Gede Agus
Published: April 2023

This normative legal study aims to analyze the application of the Pancasila economic system in Desa through BUMDes. The research focuses on two legal issues: the urgency of implementing the Pancasila economic concept in Desa and constructing Indonesia's legal framework through BUMDes practices. The research results show that Desa requires empowerment and welfare improvement, making the implementation of the Pancasila economic system crucial. BUMDes is expected to implement the Pancasila values in its economic system and prioritize fair distribution of economic resources and community welfare. The legal construction of Indonesia through BUMDes practices can be done by adopting Pancasila economic values and principles of kinship and cooperation. The implication of this study is to encourage policymakers to promote the implementation of the Pancasila economic system and BUMDes practices in empowering Desa and constructing Indonesia's legal framework.Highlights

Urgency of implementing Pancasila values in Desa for empowerment and welfare improvement.

BUMDes as a means to implement Pancasila economic system and prioritize fair distribution of resources.

Legal construction of Indonesia through adoption of Pancasila economic values and principles of kinship and cooperation.

Keywords: Pancasila economic system, BUMDes practices, Desa empowerment, Legal framework, Fair distribution.
The Evolution of Carbonate Systems During the Oligocene–Miocene Transition: An Example of Subis Limestone, Malaysia
Authors: Bing Saw Bing , Ramkumar Mu. , Rai Jyotsana , Gámez Vintaned JosÉ Antonio , Jimenez Grisel , Ali Syed Haroon , Pöppelreiter Michael
Published: April 2023

The Subis Platform is considered one of the very few outcrops in Malaysia which records remarkable changes in the growth history of a carbonate system. The Subis Platform is located near Batu Niah, Sarawak. Stratigraphically, the Subis Platform is named the Subis Limestone, a member of the Tangap Formation. This article discusses the older succession of the Subis Limestone at the Subis-2 well and the Hollystone Quarry. Both well and outcrop indicate a slightly older succession based on the occurrence of larger benthic foraminifera and calcareous nannofossils. The age of the Subis Limestone ranges from Oligocene to Miocene, based on the occurrence of the larger benthic foraminifera Miogypsinoides sp. (late Oligocene, Te4) and Miogypsina sp. (early Miocene, Te5), as well as on the calcareous nannofossils Sphenolithus capricornutus and Sphenolithus conicus (Te4). The boundary between the late Oligocene and the early Miocene coincides with a sharp change from foraminifera-dominated facies to coral-dominated facies, shown at the Hollystone Quarry. The Subis Limestone records a transgression event from mixed siliciclastic–carbonate (Subis-2 well) to clean biohermal carbonates as shown in the outcrops of the Subis quarries. Our findings on the Oligo–Miocene boundary were then compared with those from other carbonates around Southeast Asia. It is clear that coral reefs existed in Southeast Asia earlier than was first thought, by Oligocene times. The role of localized tectonic events, siliciclastic influx, oceanic mineralization, and Indonesian Throughflow are the main controls to determine the biota changes from foraminifera to coral-dominated facies.