bluuebunny/crossref_metadata_2025 huggingface dataset:
High Breakdown Strength and Energy Storage Density in Aligned SrTiO3@SiO2 Core–Shell Platelets Incorporated Polymer Composites
Authors: Chen Jie , Zhang Xiaoyong , Yang Xiao , Li Chuanyang , Wang Yifei , Chen Weixing
Published: October 2021

Dielectric nanocomposites with high energy storage density (Ue) have a strong attraction to high-pulse film energy-storage capacitors. Nevertheless, low breakdown strengths (Eb) and electric displacement difference (Dmax-Drem) values of nanocomposites with incorporating the randomly distributed high dielectric constant additions, give rise to low Ue, thereby hindering the development of energy-storage capacitors. In this study, we report on newly designed SrTiO3@SiO2 platelets/PVDF textured composites with excellent capacitive energy storage performance. SrTiO3@SiO2 platelets are well oriented in the PVDF when perpendicular to the electric field with the assistance of shear force in the flow drawing process to establish microscopic barriers in an inorganic–polymer composite that is able to substantially improve the Eb of composites and enhance the Ue accordingly. Finite element simulation demonstrates that the introduction of the highly insulating SiO2 coating onto the SrTiO3 platelets effectively alleviates the interface dielectric mismatch between filler and PVDF matrix, resulting in a reduction in the interface electric field distortion. The obtained composite film with optimized paraelectric SrTiO3@SiO2 platelets (1 vol%) exhibited a maximum Dmax-Drem value of 9.14 μC cm−2 and a maximum Ue value of 14.4 J cm−3 at enhanced Eb of 402 MV m−1, which are significantly superior to neat PVDF and existing dielectric nanocomposites.
The Natural Oligoribonucleotides Functionalized by D-Mannitol Affected Interactions of Hemagglutinin with Glycan Receptor Indicating Anti-Influenza Activity
Authors: Tkachuk Zenoviy , Melnichuk Nataliia , Nikolaiev Roman O. , Szutkowski Kosma , Zhukov Igor
Published: October 2021

Hemagglutinin (HA), the class I influenza A virus protein is responsible for the attachment of virus particles to the cell by binding to glycan receptors, subsequent virion internalization, and cell entry. Consequently, the importance of HA makes it a primary target for the development of anti-influenza drugs. The natural oligoribonucleotides (ORNs) as well as their derivatives functionalized with D-mannitol (ORNs-D-M) possess anti-influenza properties in vitro and in vivo due to interaction with HA receptor sites. This activity suppresses the viral infection in host cells. In the present work, the complexes of ORNs and ORNs-D-M with HA protein were studied by agglutination assay, fluorescence spectroscopy, as well as molecular docking simulations. Acquired experimental data exhibited a decrease in HA titer by 32 times after incubation with the ORNs-D-M for 0.5–24 h. Quenching fluorescence intensity of the HA suggests that titration by ORNs and ORNs-D-M probably leads to changes in the HA structure. Detailed structural data were obtained with the molecular docking simulations performed for ORNs and ORNs-D-M ligands containing three and six oligoribonucleotides. The results reveal that a majority of the ORNs and ORNs-D-M bind in a non-specific way to the receptor-binding domain of the HA protein. The ligand’s affinity to the hemagglutinin was estimated at the micromolar level. Presented experimental data confirmed that both natural ORNs and functionalized ORNs-D-M inhibit the interactions between HA and glycan receptors and demonstrate anti-influenza activity.
Effects of Salinity and Abscisic Acid on Lipid Transfer Protein Accumulation, Suberin Deposition and Hydraulic Conductance in Pea Roots
Authors: Akhiyarova Guzel R. , Ivanov Ruslan S. , Ivanov Igor I. , Finkina Ekaterina I. , Melnikova Daria N. , Bogdanov Ivan V. , Nuzhnaya Tatyana , Ovchinnikova Tatiana V. , Veselov Dmitriy S. , Kudoyarova Guzel R.
Published: October 2021

Lipid transfer proteins (LTPs) participate in many important physiological processes in plants, including adaptation to stressors, e.g., salinity. Here we address the mechanism of this protective action of LTPs by studying the interaction between LTPs and abscisic acid (ABA, a “stress” hormone) and their mutual participation in suberin deposition in root endodermis of salt-stressed pea plants. Using immunohistochemistry we show for the first time NaCl induced accumulation of LTPs and ABA in the cell walls of phloem paralleled by suberin deposition in the endoderm region of pea roots. Unlike LTPs which were found localized around phloem cells, ABA was also present within phloem cells. In addition, ABA treatment resulted in both LTP and ABA accumulation in phloem cells and promoted root suberization. These results suggested the importance of NaCl-induced accumulation of ABA in increasing the abundance of LTPs and of suberin. Using molecular modeling and fluorescence spectroscopy we confirmed the ability of different plant LTPs, including pea Ps-LTP1, to bind ABA. We therefore hypothesize an involvement of plant LTPs in ABA transport (unloading from phloem) as part of the salinity adaptation mechanism.
Special Issue on Drug–Membrane Interactions
Authors: Pinheiro Marina
Published: October 2021

Drug–membrane interactions immediately occur when drugs are administered, independently of the route of administration or the target location (i [...]
Surface and Bulk Oxygen Kinetics of BaCo0.4Fe0.4Zr0.2−XYXO3−δ Triple Conducting Electrode Materials
Authors: Duffy Jack , Meng Yuqing , Abernathy Harry , Brinkman Kyle
Published: October 2021

Triple ionic-electronic conductors have received much attention as electrode materials. In this work, the bulk characteristics of oxygen diffusion and surface exchange were determined for the triple-conducting BaCo0.4Fe0.4Zr0.2−XYXO3−δ suite of samples. Y substitution increased the overall size of the lattice due to dopant ionic radius and the concomitant formation of oxygen vacancies. Oxygen permeation measurements exhibited a three-fold decrease in oxygen permeation flux with increasing Y substitution. The DC total conductivity exhibited a similar decrease with increasing Y substitution. These relatively small changes are coupled with an order of magnitude increase in surface exchange rates from Zr-doped to Y-doped samples as observed by conductivity relaxation experiments. The results indicate that Y-doping inhibits bulk O2− conduction while improving the oxygen reduction surface reaction, suggesting better electrode performance for proton-conducting systems with greater Y substitution.
A Study to Enhance the Nitrate-Nitrogen Removal Rate without Dismantling the NF Module by Building a PFSA Ionomer-Coated NF Module
Authors: Park In-Kee , Hou Jian , Yun Jaehan , Lee Hee-Dae , Lee Chang-Hyun
Published: October 2021

Water resource pollution by nitrate-nitrogen, mainly caused by anthropogenic causes, induces eutrophication of water resources, and indicates the degree of organic pollution. Therefore, this study devised a method for coating PFSA ionomer with excellent chemical resistance without disassembling the module to improve the removal rate of nitrate-nitrogen in water by using a cyclic coating method on a commercially available nanofiltration membrane (NF membrane) module. Nafion was prepared as a supercritical fluid dispersion using a high-temperature and high-pressure reactor, and the particle size and the degree of dispersion of the dispersion were analyzed by DLS. The crystallinity was confirmed through XRD by drying the dispersion in the liquid state. After the dispersion was prepared as a membrane according to the heat treatment conditions, the characteristics according to the particle size were analyzed by tensile strength and TEM. The nitrate-nitrogen removal rate of the NF membrane module coated with the dispersion was increased by 93% compared to that before coating. Therefore, the result showed that the cycle coating method devised in this study could efficiently coat the already commercialized module and improve performance.
The Cytoplasmic Tail of Influenza A Virus Hemagglutinin and Membrane Lipid Composition Change the Mode of M1 Protein Association with the Lipid Bilayer
Authors: Kordyukova Larisa V. , Konarev Petr V. , Fedorova Nataliya V. , Shtykova Eleonora V. , Ksenofontov Alexander L. , Loshkarev Nikita A. , Dadinova Lubov A. , Timofeeva Tatyana A. , Abramchuk Sergei S. , Moiseenko Andrei V. , Baratova Lyudmila A. , Svergun Dmitri I. , Batishchev Oleg V.
Published: October 2021

Influenza A virus envelope contains lipid molecules of the host cell and three integral viral proteins: major hemagglutinin, neuraminidase, and minor M2 protein. Membrane-associated M1 matrix protein is thought to interact with the lipid bilayer and cytoplasmic domains of integral viral proteins to form infectious virus progeny. We used small-angle X-ray scattering (SAXS) and complementary techniques to analyze the interactions of different components of the viral envelope with M1 matrix protein. Small unilamellar liposomes composed of various mixtures of synthetic or “native” lipids extracted from Influenza A/Puerto Rico/8/34 (H1N1) virions as well as proteoliposomes built from the viral lipids and anchored peptides of integral viral proteins (mainly, hemagglutinin) were incubated with isolated M1 and measured using SAXS. The results imply that M1 interaction with phosphatidylserine leads to condensation of the lipid in the protein-contacting monolayer, thus resulting in formation of lipid tubules. This effect vanishes in the presence of the liquid-ordered (raft-forming) constituents (sphingomyelin and cholesterol) regardless of their proportion in the lipid bilayer. We also detected a specific role of the hemagglutinin anchoring peptides in ordering of viral lipid membrane into the raft-like one. These peptides stimulate the oligomerization of M1 on the membrane to form a viral scaffold for subsequent budding of the virion from the plasma membrane of the infected cell.
Design and Implementation of an Electrical Characterization System for Membrane Capacitive Deionization Units for the Water Treatment
Authors: Leon Federico A. , Ramos-Martin Alejandro , Santana David
Published: October 2021

The desalination of seawater is one of the most established techniques in the world. In the middle of the 20th century this was achieved using water evaporation systems, later with reverse osmosis membranes and nowadays with the possibility of capacitive deionization membranes. Capacitive deionization and membrane capacitive deionization are an emerging technology that make it possible to obtain drinking water with an efficiency of 95%. This technology is in the development stage and consists of porous activated carbon electrodes, which have great potential for saving energy in the water desalination process and can be used for desalination using an innovative technology called capacitive deionization (CDI), or membrane capacitive deionization (MCDI) if an anion and cation membrane exchange is used. In this paper is proposed and designed a characterization system prototype for CDI and MCDI that can operate with constant current charging and discharging (galvanostatic method). Adequate precision has been achieved, as can be seen in the results obtained. These results were obtained from the performance of typical characterization tests with electrochemical double layer capacitors (EDLC), since they are electrochemical devices that behave similarly to MCDI, from the point of view of the electrical variables of the processes that take place in MCDI. A philosophy of using free software with open-source code has been followed, with software such as the Arduino and Processing programming editors (IDE), as well as the Arduino Nano board (ATmega328), the analogical-digital converter (ADC1115) and the digital-analogical converter (MCP4725). Moreover, a low-cost system has been developed. A robust and versatile system has been designed for water treatment, and a flexible system has been obtained for the specifications established, as it is shown in the results section.
Performance Analysis of a Full-Scale Desalination Plant with Reverse Osmosis Membranes for Irrigation
Authors: Leon Federico , Ramos Alejandro
Published: October 2021

Reverse osmosis (RO) is the most widely used technology for seawater desalination purposes. The long-term operating data of full-scale plants is key to analyse their performance under real conditions. The studied seawater reverse osmosis (SWRO) desalination plant had a production capacity of 5000 m3/d for irrigation purposes. The operating data such as conductivities flows, and pressures were collected for around 27,000 h for 4 years. The plant had sand and cartridge filters without chemical dosing in the pre-treatment stage, a RO system with one stage, 56 pressure vessels, seven RO membrane elements per pressure vessel and a Pelton turbine as energy recovery device. The operating data allowed to calculate the average water and salt permeability coefficients (A and B) of the membrane as well as the specific energy consumption (SEC) along the operating period. The calculation of the average A in long-term operation allowed to fit the parameters of three different models used to predict the mentioned parameter. The results showed a 30% decrease of A, parameter B increase around 70%. The SEC was between 3.75 and 4.25 kWh/m3. The three models fitted quite well to the experimental data with standard deviations between 0.0011 and 0.0015.
Microstructure and Nanoindentation Behavior of Ti40Zr40Ni20 Quasicrystal Alloy by Casting and Rapid Solidification
Authors: Hou Junli , Yang Zhong , Duan Hongbo , Feng Yiyi , Guo Yongchun , Li Jianping
Published: October 2021

A Ti40Zr40Ni20 quasicrystal (QCs) rod and ribbons were prepared by conventional casting and rapid solidification. The X-ray diffractometry (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and differential scanning calorimeter (DSC) techniques were used to investigate the microtissue, phase composition, and solidification features of the samples; the nano-indentation test was carried out at room temperature. The results show that a mixture of the α-Ti(Zr) phase and the icosahedral quasicrystal (I-phase) was formed in the Ti40Zr40Ni20 rod; the microstructure of Ti40Zr40Ni20 ribbons mainly consisted of the I-phase. The solidification mechanism of the I-phase was different in the two alloys. The I-phase in the quasicrystalline rod was formed by packet reaction while in the ribbons it was generated directly from the liquid. At room temperature, both samples had relatively high hardness and elastic modulus; the elastic modulus of the ribbons is 76 GPa, higher than the 45 GPa of the rod. The hardness of the ribbons was more than twice that of the rod.
Evaluation of the Possibility of Obtaining Welded Joints of Plates from Al-Mg-Mn Aluminum Alloys, Strengthened by the Introduction of TiB2 Particles
Authors: Zhukov Ilya , Kozulin Alexander , Khrustalyov Anton , Tkachev Dmitrii , Platov Vladimir , Nikitin Pavel , Vorozhtsov Alexander
Published: October 2021

In the work, the possibility of obtaining strong welded joints of aluminum alloys modified with particles is demonstrated. For research, strengthened aluminum alloys of the Al-Mg-Mn system with the introduction of TiB2 particles were obtained. TiB2 particles in specially prepared Al-TiB master alloys obtained by self-propagating high-temperature synthesis were introduced ex situ into the melt according to an original technique using ultrasonic treatment. Plates from the studied cast alloys were butt-welded by one-sided welded joints of various depths. To obtain welded joints, the method of electron beam welding was used. Mechanical properties of the studied alloys and their welded joints under tension were studied. It was shown that the introduction of particles resulted in a change in the internal structure of the alloys, characterized by the formation of compact dendritic structures and a decrease in the average grain size from 155 to 95 µm. The change in the internal structure due to the introduction of particles led to an increase in the tensile strength of the obtained alloys from 163 to 204 MPa. It was found that the obtained joints have sufficient relative strength values. Relative strength values reach 0.9 of the nominal strength of materials already at the ratio of the welded joint depth to the thickness of the welded plates, equal to 0.6 for the initial alloy and in the range of 0.67–0.8 for strengthened alloys.
Chalcopyrite Leaching with Hydrogen Peroxide and Iodine Species in Acidic Chloride Media at Room Temperature: Technical and Economic Evaluation
Authors: Moraga Germán A. , Jamett Nathalie E. , Hernández Pía C. , Graber Teófilo A. , Taboada María E.
Published: October 2021

In Chile, the hydrometallurgical plants are operating below their capacity due to a depletion of copper oxide ores. To obtain suitable pregnant leach solutions (PLSs) for hydrometallurgical plants, leaching solutions combining iodine-based oxidants and hydrogen peroxide in a chloride–acid medium, at room temperature and pressure were studied. Factorial experiments were conducted to evaluate the effects of the different leaching solution reagents (KI, NaIO3, NaCl, H2O2, and H2SO4). The results showed that the most influential variable is the H2O2 concentration; increasing the PLS concentration from 3 g/L to 15 g/L increased the copper extraction percentage by ~25%. In decreasing order of importance, the factorial experimental results showed that the H2O2, H2SO4, NaCl, NaIO3, and KI concentrations affect the copper extraction percentage. The highest copper extraction percentage (i.e., 60.6%) was obtained using a leaching solution containing the highest reagent concentrations. At these conditions, the copper concentration in the PLS was 16.9 g/L. An economic evaluation of the laboratory-scale leaching experiments showed an increase in the unit cost (USD/t Cu) for experiments involving leaching solutions without H2O2 because of poor copper concentration in the PLS. As the concentrations of the reagents NaIO3 and KI, increase, the unit cost increases, because the reagents are relatively expensive and have a limited effect on the copper extraction percentage.
Strain Amplitude Dependence of High Damping Grp/Mg97Zn1Y2 Composites Ranging from Anelastic to Microplastic
Authors: Wan Diqing , Dong Shaoyun , Hu Yinglin , Hu Jiajun , Xue Yandan , Han Guoliang
Published: October 2021

In this paper, the damping capacities and damping mechanisms of high damping, graphite-reinforced Mg97Zn1Y2 composites were investigated. Composites consisting of different graphite particle sizes (24, 11, and 3 μm) were designed and prepared using the casting method. The microstructure of the composites was examined using optical microscopy (OM) and transmission electron microscopy (TEM), which confirmed that the graphite particles were successfully planted into the Mg97Zn1Y2 matrix. Measurements made with a dynamic mechanical analyzer (DMA) showed that the Grp/Mg97Zn1Y2 composite has a high damping capacity. At the anelastic strain amplitude stage, the damping properties of the Grp/Mg97Zn1Y2 composites were found to be higher than those of the Mg97Zn1Y2 alloy. Furthermore, decreasing the graphite particle size was found to improve the damping properties of the Grp/Mg97Zn1Y2 composites. At the microplastic strain amplitude stage, the damping properties of the Mg97Zn1Y2 alloy were found to be higher than those of the Grp/Mg97Zn1Y2 composites. Moreover, the damping properties of the Grp/Mg97Zn1Y2 composites were found to decrease with increasing graphite particle size. The reason for the increased damping of the Grp/Mg97Zn1Y2 composites during the anelastic strain amplitude stage can be attributed to the increase in the number of damping sources and weak interactions among the dislocation damping mechanisms. At the microplastic strain amplitude stage, the damping properties of the composite are mainly affected by the activation volume of the slipped dislocation.
Anodized Biomedical Stainless-Steel Mini-Implant for Rapid Recovery in a Rabbit Model
Authors: Cho Yung-Chieh , Hung Wei-Chiang , Lan Wen-Chien , Saito Takashi , Huang Bai-Hung , Lee Chen-Han , Tsai Hsin-Yu , Huang Mao-Suan , Ou Keng-Liang
Published: October 2021

The study aimed to analyze the recovery period of the anodized 316L biomedical stainless steel (BSS) mini-implant through its implantation on femur of rabbit model. The 316L BSS mini-implant was modified by an electrochemical anodization approach with different voltages. The anodized samples were characterized via field-emission scanning electron microscopy, X-ray diffractometry, and X-ray photoelectron spectroscopy. The biocompatibility was assessed by cell culture assay. The anodized mini-implant was implanted on rabbit’s femur then evaluated histologically after 4 and 8 weeks. Analytical results indicated that the topography of the anodized mini-implant at 5 V for 5 min consisted of a dual (micro/nano) porous structure. Oxide film of Cr2O3 was formed on the surface of anodized mini-implant after anodizing with 5 V for 5 min. In vitro cell culture assay revealed that fibroblast cells (NIH-3T3) on the anodized samples were more firmly attached as compared with the control sample. Moreover, histological analysis demonstrated that the anodized mini-implant improved bone recovering at 4 weeks after implantation. Thus, this study suggests that the anodized 316L BSS mini-implant could be a potential choice as anchorage device for effective and efficient orthodontic treatment.
Dissimilar Laser Welding of a NiTi Shape Memory Alloy to Ti2AlNb
Authors: Ge Fuguo , Peng Bei , Oliveira João Pedro , Ke Wenchao , Teshome Fissha Biruke , Li Yongmei , Zeng Zhi
Published: October 2021

NiTi-based shape memory alloys and the Ti2AlNb alloy have gained increasing importance in the aerospace field. The joining of these two materials can further increment the importance and usage of these relevant engineering materials and expand their potential applications. However, when joining NiTi-based shape memory alloys to Ti-based alloys, the formation of brittle Ti-rich intermetallic compounds often occurs, significantly limiting their functionality and use. Dissimilar joints between a NiTi shape memory alloy and Ti2AlNb alloy were obtained using a 0.1 mm thick Niobium (Nb) interlayer via laser welding. By process optimization, sound joints were obtained. The microstructure evolution was assessed by means of electron microscopy, whereas the mechanical strength of the joints was evaluated using lap shear tensile testing. The best performing joints were seen to fracture at maximum loads above 1230 N, thus allowing us to consider this dissimilar pair for structural applications.
Hydration Activity and Carbonation Characteristics of Dicalcium Silicate in Steel Slag: A Review
Authors: Na Hao , Wang Yajun , Zhang Xi , Li Junguo , Zeng Yanan , Liu Pengyao
Published: October 2021

Dicalcium silicate is one of the main mineral phases of steel slag. Ascribed to the characteristics of hydration and carbonation, the application of slag in cement production and carbon dioxide sequestration has been confirmed as feasible. In the current study, the precipitation process of the dicalcium silicate phase in steel slag was discussed. Meanwhile, the study put emphasis on the influence of different crystal forms of dicalcium silicate on the hydration activity and carbonation characteristics of steel slag. It indicates that most of the dicalcium silicate phase in steel slag is the γ phase with the weakest hydration activity. The hydration activity of γ-C2S is improved to a certain extent by means of mechanical, high temperature, and chemical activation. However, the carbonation activity of γ-C2S is about two times higher than that of β-C2S. Direct and indirect carbonation can effectively capture carbon dioxide. This paper also summarizes the research status of the application of steel slag in cement production and carbon dioxide sequestration. Further development of the potential of dicalcium silicate hydration activity and simplifying the carbonation process are important focuses for the future.
Low-Carbon Ti-Mo Microalloyed Hot Rolled Steels: Special Features of the Formation of the Structural State and Mechanical Properties
Authors: Zaitsev Alexander , Arutyunyan Nataliya
Published: October 2021

Low-carbon Ti-Mo microalloyed steels represent a new generation of high strength steels for automobile sheet. Excellent indicators of difficult-to-combine technological, strength, and other service properties are achieved due to the superposition of a dispersed ferrite matrix and a bulk system of nanoscale carbide precipitates. Recently, developments are underway to optimize thermo-deformation processing for the most efficient use of phase precipitates. The review summarizes and analyzes the results of studies of mechanical properties depending on the chemical composition and parameters of hot deformation of low-carbon Ti-Mo microalloyed steels. Particular attention is paid to the features of the formation and the influence of various types of phase precipitates and the dispersion of the microstructure on mechanical properties. The advantages of Ti-Mo microalloying system and the tasks requiring further solution are shown.
Extraction of Cu(II), Fe(III), Zn(II), and Mn(II) from Aqueous Solutions with Ionic Liquid R4NCy
Authors: Castillo Jonathan , Toro Norman , Hernández Pía , Navarro Patricio , Vargas Cristian , Gálvez Edelmira , Sepúlveda Rossana
Published: October 2021

The leaching of copper ores produces a rich solution with metal interferences. In this context, Fe(III), Zn(II), and Mn(II) are three metals contained in industrial copper-rich solutions in high quantities and eventually can be co-extracted with the copper. The purpose of the current study was to determine the feasibly of solvent extraction with the use of ionic liquid methyltrioctyl/decylammonium bis (2,4,4-trimethylpentyl)phosphinate (R4NCy) as an extractant of Cu(II) in the presence of Fe(III), Zn(II), and Mn(II). In general terms, the results showed a high single extraction efficiency of all the metals under study. In the case of Fe(III) and Zn(II), the extraction was close to 100%. On the contrary, the stripping efficiency was poor to Fe(III) and discrete to Zn(II), but very high to Cu(II) and Mn(II). Finally, the findings of this study suggest that the ionic liquid R4NCy is feasible for the pre-treatment of the copper solvent extraction process to remove metal impurities such as Fe(III) and Zn(II).
Lift-Off Ablation of Metal Thin Films for Micropatterning Using Ultrashort Laser Pulses
Authors: Kim Byunggi , Nam Han-Ku , Kim Young-Jin , Kim Seung-Woo
Published: October 2021

Laser ablation of metal thin films draws attention as a fast means of clean micropatterning. In this study, we attempt to remove only the metal thin film layer selectively without leaving thermal damage on the underneath substrate. Specifically, our single-pulse ablation experiment followed by two-temperature analysis explains that selective ablation can be achieved for gold (Au) films of 50–100 nm thickness by the lift-off process induced as a result of vaporization of the titanium (Ti) interlayer with a strong electron–phonon coupling. With increasing the film thickness comparable to the mean free path of electrons (100 nm), the pulse duration has to be taken shorter than 10 ps, as high-temperature electrons generated by the ultrashort pulses transfer heat to the Ti interlayer. We verify the lift-off ablation by implementing millimeters-scale micropatterning of optoelectronic devices without degradation of optical properties.
Thermophysical Model for Online Optimization and Control of the Electric Arc Furnace
Authors: Jawahery Sudi , Visuri Ville-Valtteri , Wasbø Stein O. , Hammervold Andreas , Hyttinen Niko , Schlautmann Martin
Published: October 2021

A dynamic, first-principles process model for a steelmaking electric arc furnace has been developed. The model is an integrated part of an application designed for optimization during operation of the furnace. Special care has been taken to ensure that the non-linear model is robust and accurate enough for real-time optimization. The model is formulated in terms of state variables and ordinary differential equations and is adapted to process data using recursive parameter estimation. Compared to other models available in the literature, a focus of this model is to integrate auxiliary process data in order to best predict energy efficiency and heat transfer limitations in the furnace. Model predictions are in reasonable agreement with steel temperature and weight measurements. Simulations indicate that industrial deployment of Model Predictive Control applications derived from this process model can result in electrical energy consumption savings of 1–2%.
Molten Pool Behaviors in Double-Sided Pulsed GMAW of T-Joint: A Numerical Study
Authors: Zhang Haicang , Wang Chunsheng , Lin Sanbao
Published: October 2021

The T-joint is one of the essential types of joints in aluminum welded structures. Double-sided welding is a preferable solution to maintain high efficiency and avoid significant distortion during T-joint welding. However, interactions between double-sided molten pools make flow behaviors complicated during welding. Numerical simulations regarding molten pool behaviors were conducted in this research to understand the complex flow phenomenon. The influences of wire feed rates and torch distances were simulated and discussed. The results show that droplet impinging drives the fluid to flow down to the root and form a frontward vortex. Marangoni stress forces the fluid to form an outward vortex near the molten pool boundary and flatten the concave-shaped molten pool surface. With an increased wire feed speed, the volume of the molten pool increases, and the root fusion is improved. With an increased torch distance, the width of the front molten pool decreases while the length increases, and the rear molten pool size decreases slightly. Both wire feed speeds and the torch distances have limited influences on the basic flow characteristics.
Demonstration of Threshold Switching and Bipolar Resistive Switching in Ag/SnOx/TiN Memory Device
Authors: Pyo Juyeong , Woo Seung-Jin , Lee Kisong , Kim Sungjun
Published: October 2021

In this work, we observed the duality of threshold switching and non-volatile memory switching of Ag/SnOx/TiN memory devices by controlling the compliance current (CC) or pulse amplitude. The insulator thickness and chemical analysis of the device stack were confirmed by transmission electron microscope (TEM) images of the Ag/SnOx/TiN stack and X-ray photoelectron spectroscopy (XPS) of the SnOx film. The threshold switching was achieved at low CC (50 μA), showing volatile resistive switching. Optimal CC (5 mA) for bipolar resistive switching conditions with a gradual transition was also found. An unstable low-resistance state (LRS) and negative-set behavior were observed at CCs of 1 mA and 30 mA, respectively. We also demonstrated the pulse operation for volatile switching, set, reset processes, and negative-set behaviors by controlling pulse amplitude and polarity. Finally, the potentiation and depression characteristics were mimicked by multiple pulses, and MNIST pattern recognition was calculated using a neural network, including the conductance update for a hardware-based neuromorphic system.
A Numerical and Experimental Assessment of the Small Punch Creep Test for 316L(N) Stainless Steels
Authors: Nilsson Karl-Fredrik , Baraldi Daniele , Holmström Stefan , Simonovski Igor
Published: October 2021

This paper presents a finite element analysis of the small punch creep test for 316L(N), which is compared with experimental data for 650 and 700 °C. Special emphasis is placed on (i) assessing the influence of friction and (ii) comparing two different creep models: the simple Norton creep and the more general creep model. The computed normalized deflection rate versus time is almost identical for all cases, which allows for scaling of the results. The computed time to rupture increases linearly with the friction coefficient due to a reduction in the mean stress. There is a good overall agreement between the experimental values and the computed deflection rate for a friction coefficient of around 0.3. It is shown that the initial reduction in deflection rate is due to stress relaxation and homogenization, and is only marginally affected by primary creep hardening. The computed results are compared with the equivalent stress and strain rates in the recently published small punch standard (EN 10371). The computed von Mises stresses at minimum deflection decrease linearly with the friction coefficient but are consistently slightly higher than the equivalent stress in the standard. For the strain rates, the computed values are significantly higher than the equivalent values in the standard. The presented simulations give a deeper insight of the small punch creep and impact of key parameters such the friction coefficient and in general as a guidance to refinement and improvement of the empirically based formulae in the standard.
Association of Dietary Nutrient Intake with Early Age-Related Macular Degeneration in Japanese-Americans
Authors: Edo Ayaka , Pertiwi Yunialthy Dwia , Hirooka Kazuyuki , Masuda Shun , Kamaruddin Muhammad Irfan , Yanagi Masahide , Nagao Akiko , Ohno Haruya , Yoneda Masayasu , Kiuchi Yoshiaki
Published: October 2021

Lifestyle factors may be associated with the development of age-related macular degeneration (AMD), in addition to demographic and genetic factors. The purpose of this cross-sectional study is to elucidate the association between nutrient intake and AMD in the Japanese-American population living in Los Angeles. We conducted a medical survey of Japanese immigrants and their descendants living in Los Angeles, including interviews on dietary habits, fundus photography, and physical examinations. Participants were classified into early AMD and control groups on the basis of fundus photographic findings. Consequently, among the 555 participants, 111 (20.0%) were diagnosed with early AMD. There were no late-stage AMD participants. Multivariate logistic regression analysis showed that the intake of animal fat and saturated fatty acids (SFA) was positively associated with early AMD (p for trend = 0.01 for animal fat, p for trend = 0.02 for SFA), and the intake of vegetable fat, total carbohydrate, simple carbohydrate, sugar, and fructose was inversely associated with early AMD (p for trend = 0.04 for vegetable fat, p for trend = 0.046 for carbohydrate, p for trend = 0.03 for simple carbohydrate, p for trend = 0.046 for sugar, p for trend = 0.02). Our findings suggest that excessive animal fat and SFA intake increases the risk for early AMD in Japanese-Americans whose lifestyles have been westernized.
How Ceramides Orchestrate Cardiometabolic Health—An Ode to Physically Active Living
Authors: Carrard Justin , Gallart-Ayala Hector , Weber Nadia , Colledge Flora , Streese Lukas , Hanssen Henner , Schmied Christian , Ivanisevic Julijana , Schmidt-Trucksäss Arno
Published: October 2021

Cardiometabolic diseases (CMD) represent a growing socioeconomic burden and concern for healthcare systems worldwide. Improving patients’ metabolic phenotyping in clinical practice will enable clinicians to better tailor prevention and treatment strategy to individual needs. Recently, elevated levels of specific lipid species, known as ceramides, were shown to predict cardiometabolic outcomes beyond traditional biomarkers such as cholesterol. Preliminary data showed that physical activity, a potent, low-cost, and patient-empowering means to reduce CMD-related burden, influences ceramide levels. While a single bout of physical exercise increases circulating and muscular ceramide levels, regular exercise reduces ceramide content. Additionally, several ceramide species have been reported to be negatively associated with cardiorespiratory fitness, which is a potent health marker reflecting training level. Thus, regular exercise could optimize cardiometabolic health, partly by reversing altered ceramide profiles. This short review provides an overview of ceramide metabolism and its role in cardiometabolic health and diseases, before presenting the effects of exercise on ceramides in humans.
Clinical Predictors of Mortality and Critical Illness in Patients with COVID-19 Pneumonia
Authors: Basheer Maamoun , Saad Elias , Hagai Rechnitzer , Assy Nimer
Published: October 2021

Early identification of patients with COVID-19 who will develop severe or critical disease symptoms is important for delivering proper and early treatment. We analyzed demographic, clinical, immunological, hematological, biochemical and radiographic findings that may be of utility to clinicians in predicting COVID-19 severity and mortality. Electronic medical record data from patients diagnosed with COVID-19 from November 2020 to June 2021 in the COVID-19 Department in the Galilee Medical Center, Nahariya, Israel, were collected. Epidemiologic, clinical, laboratory and imaging variables were analyzed. Multivariate stepwise regression analyses and discriminant analyses were used to identify and validate powerful predictors. The main outcome measure was invasive ventilation, or death. The study population included 390 patients, with a mean age of 61 ± 18, and 51% were male. The non-survivors were mostly male, elderly and overweight and significantly suffered from hypertension, diabetes mellitus type 2, lung disease, hemodialysis and past use of aspirin. Four predictive factors were found that associated with increased disease severity and/or mortality: age, NLR, BUN, and use of high flow oxygen therapy (HFNC). The AUC or diagnostic accuracy was 87%, with a sensitivity of 97%, specificity of 60%, PPV of 87% and NPP of 91%. The cytokine levels of CXCL-10, GCSF, IL-2 and IL-6 were significantly reduced upon the discharge of severely ill COVID-19 patients. The predictive factors associated with increased mortality include age, NLR, BUN, and use of HFNC upon admission. Identifying those with higher risks of mortality could help in early interventions to reduce the risk of death.
Gallstone Formation Follows a Different Trajectory in Bariatric Patients Compared to Nonbariatric Patients
Authors: Haal Sylke , Guman Maimoena S. S. , Acherman Yair I. Z. , Jansen Johannes P. G. , van Weeghel Michel , van Lenthe Henk , Wever Eric J. M. , Gerdes Victor E. A. , Voermans Rogier P. , Groen Albert K.
Published: October 2021

Since obese patients form cholesterol gallstones very rapidly after bariatric surgery, in patients who did not form gallstones during preceding years, we hypothesized that gallstone formation follows a different trajectory in bariatric patients compared to nonbariatric patients. We therefore analyzed the lipid composition of gallbladder bile derived from 18 bariatric gallstone patients and 17 nonbariatric gallstone patients (median (IQR) age, 46.0 (28.0–54.0) years; 33 (94%) female) during laparoscopic cholecystectomy using an enzymatic and lipidomics approach. We observed a higher concentration of total lipids (9.9 vs. 5.8 g/dL), bile acids (157.7 vs. 81.5 mM), cholesterol (10.6 vs. 5.4 mM), and phospholipids (30.4 vs. 21.8 mM) in bariatric gallstone patients compared to nonbariatric gallstone patients. The cholesterol saturation index did not significantly differ between the two groups. Lipidomics analysis revealed an interesting pattern. Enhanced amounts of a number of lipid species were found in the gallbladder bile of nonbariatric gallstone patients. Most striking was a fivefold higher amount of triglyceride. A concomitant ninefold increase of apolipoprotein B was found, suggesting secretion of triglyceride-rich lipoproteins (TRLs) at the canalicular pole of the hepatocyte in livers from nonbariatric gallstone patients. These findings suggest that gallstone formation follows a different trajectory in bariatric patients compared to nonbariatric patients. Impaired gallbladder emptying might explain the rapid gallstone formation after bariatric surgery, while biliary TRL secretion might contribute to gallstone formation in nonbariatric patients.
The “Common Soil Hypothesis” Revisited—Risk Factors for Type 2 Diabetes and Cardiovascular Disease
Authors: Fernandes Silva Lilian , Vangipurapu Jagadish , Laakso Markku
Published: October 2021

The prevalence and the incidence of type 2 diabetes (T2D), representing >90% of all cases of diabetes, are increasing rapidly worldwide. Identification of individuals at high risk of developing diabetes is of great importance, as early interventions might delay or even prevent full-blown disease. T2D is a complex disease caused by multiple genetic variants in interaction with lifestyle and environmental factors. Cardiovascular disease (CVD) is the major cause of morbidity and mortality. Detailed understanding of molecular mechanisms underlying in CVD events is still largely missing. Several risk factors are shared between T2D and CVD, including obesity, insulin resistance, dyslipidemia, and hyperglycemia. CVD can precede the development of T2D, and T2D is a major risk factor for CVD, suggesting that both conditions have common genetic and environmental antecedents and that they share “common soil”. We analyzed the relationship between the risk factors for T2D and CVD based on genetics and population-based studies with emphasis on Mendelian randomization studies.
The Improvement in Hydrogen Storage Performance of MgH2 Enabled by Multilayer Ti3C2
Authors: Wu Zhaojie , Fang Jianhua , Liu Na , Wu Jiang , Kong Linglan
Published: October 2021

MgH2 has become a hot spot in the research of hydrogen storage materials, due to its high theoretical hydrogen storage capacity. However, the poor kinetics and thermodynamic properties of hydrogen absorption and desorption seriously hinder the development of this material. Ti-based materials can lead to good effects in terms of reducing the temperature of MgH2 in hydrogen absorption and desorption. MXene is a novel two-dimensional transition metal carbide or carbonitride similar in structure to graphene. Ti3C2 is one of the earliest and most widely used MXenes. Single-layer Ti3C2 can only exist in solution; in comparison, multilayer Ti3C2 (ML-Ti3C2) also exists as a solid powder. Thus, ML-Ti3C2 can be easily composited with MgH2. The MgH2+ML-Ti3C2 composite hydrogen storage system was successfully synthesized by ball milling. The experimental results show that the initial desorption temperature of MgH2-6 wt.% ML-Ti3C2 is reduced to 142 °C with a capacity of 6.56 wt.%. The Ea of hydrogen desorption in the MgH2-6 wt.% ML-Ti3C2 hydrogen storage system is approximately 99 kJ/mol, which is 35.3% lower than that of pristine MgH2. The enhancement of kinetics in hydrogen absorption and desorption by ML-Ti3C2 can be attributed to two synergistic effects: one is that Ti facilitates the easier dissociation or recombination of hydrogen molecules, while the other is that electron transfer generated by multivalent Ti promotes the easier conversion of hydrogen. These findings help to guide the hydrogen storage properties of metal hydrides doped with MXene.
Advanced Infill Designs for 3D Printed Shape-Memory Components
Authors: Koske Daniel , Ehrmann Andrea
Published: October 2021

Poly(lactic acid) (PLA) is one of the most often used polymers in 3D printing based on the fused deposition modeling (FDM) method. On the other hand, PLA is also a shape memory polymer (SMP) with a relatively low glass transition temperature of ~60 °C, depending on the exact material composition. This enables, on the one hand, so-called 4D printing, i.e., printing flat objects which are deformed afterwards by heating them above the glass transition temperature, shaping them and cooling them down in the desired shape. On the other hand, objects from PLA which have been erroneously deformed, e.g., bumpers during an accident, can recover their original shape to a certain amount, depending on the applied temperature, the number of deformation cycles, and especially on the number of broken connections inside the object. Here, we report on an extension of a previous study, investigating optimized infill designs which avoid breaking in 3-point bending tests and thus allow for multiple repeated destruction and recovery cycles with only a small loss in maximum force at a certain deflection.
Study on the Absorption Characteristics and Laser Damage Properties of Fused Silica Optics under Flexible Polishing and Shallow DCE Process
Authors: Zhang Wanli , Shi Feng , Song Ci , Tian Ye , Shen Yongxiang
Published: October 2021

The enhancement of laser damage resistance of fused silica optics was a hotspot in scientific research. At present, a variety of modern processes have been produced to improve the laser induced damage threshold (LIDT) of fused silica optics. They included pre-treatment processes represented by flexible computer controlled optical surfacing (CCOS), magnetorheological finishing (MRF), ion beam finishing (IBF), and post-treatment processes represented by dynamic chemical etching (DCE). These have achieved remarkable results. However, there are still some problems that need to be solved urgently, such as excessive material removal, surface accuracy fluctuation in the DCE process, and the pollution in MRF process, etc. In view of above problems, an MRF, CCOS, IBF and shallow DCE combined technique was used to process fused silica optics. The surface morphology could be greatly controlled and chemical etching depth was reduced, while the LIDT increased steadily. After processing by this combined technique, the LIDT increased to 12.1 J/cm2 and the laser damage resistance properties of fused silica were significantly enhanced. In general, the MRF, IBF, CCOS and shallow DCE combined technique brought much help to the enhancement of laser damage resistance of fused silica, and could be used as a process route in the manufacturing process of fused silica.