bluuebunny/crossref_metadata_2025 huggingface dataset:
Occupational Health Hazards Among Traffic Police in South Asian Countries: Protocol for a Scoping Review
Authors: Jahan Ishrat , Dalal Koustuv , Khan Md Abdullah Saeed , Mutsuddi Archi , Sultana Sabeeha , Rashid Md Utba , Haque Miah Md Akiful , Hossain Mohammad Ali , Hossian Mosharop , Nabi Mohammad Hayatun , Hawlader Mohammad Delwer Hossain
Published: December 2022

Background

Occupational health hazards and injuries are an alarming concern among traffic police. Occupational injuries affect the physical, social, and mental well-being of police personnel, which has various public health implications. The evaluation of occupational health and safety policies and regulations for the traffic police relies on their occupational exposure and health hazard statistics and assessments.

Objective

The purpose of this scoping review is to systematically explore, analyze, and describe relevant findings from all studies conducted on occupational exposure and associated health hazards among traffic police in South Asia.

Methods

The scoping review will include studies that assessed occupational exposure prevalence, types, knowledge, predisposing factors, and prevention strategies. Databases like PubMed, Springer Link, EBSCOhost, the Cochrane library, and Google Scholar will be used to obtain both published and unpublished works in the English language. Relevant gray literature, including governmental and international organization reports, will be examined. After removing duplicates and screening titles and abstracts, the full-text analysis will begin. Arksey and O'Malley's methodology framework for scoping reviews will be followed. According to Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews, the scoping review will be reported. Two qualified reviewers will independently conduct article screening and data extraction. The extracted data will then be tabulated and accompanied by an explanation to facilitate comprehension. We will extract relevant article results using NVivo (version 10; QSR International) and thematic content analysis. The included articles will be evaluated using the mixed methods appraisal tool (version 2018).

Results

The scoping review will provide insight into how occupational health hazards affect traffic police physically and psychologically in South Asia. The theoretical conceptualization of different aspects of the occupational health of traffic police will emphasize future studies in this region, which will inform policy makers to revise their occupational health and safety policies and principles. It will have implications for taking necessary preventive measures in the future to reduce occupational injuries and fatalities resulting from different types of occupational hazards.

Conclusions

This scoping review will describe the overview of occupational hazards among South Asian traffic police and will provide insights for policy makers to implement changes and to adapt new strategies.

International Registered Report Identifier (IRRID)

PRR1-10.2196/42239
The Role of Social Media in Knowledge, Perceptions, and Self-Reported Adherence Toward COVID-19 Prevention Guidelines: Cross-Sectional Study (Preprint)
Authors: Garrett Camryn , Qiao Shan , Li Xiaoming
Published: December 2022

BACKGROUND

Throughout the COVID-19 pandemic, social media has served as a channel of communication, a venue for entertainment, and a mechanism for information dissemination.

OBJECTIVE

This study aims to assess the associations between social media use patterns; demographics; and knowledge, perceptions, and self-reported adherence toward COVID-19 prevention guidelines, due to growing and evolving social media use.

METHODS

Quota-sampled data were collected through a web-based survey of US adults through the Qualtrics platform, from March 15, 2022, to March 23, 2022, to assess covariates (eg, demographics, vaccination, and political affiliation), frequency of social media use, social media sources of COVID-19 information, as well as knowledge, perceptions, and self-reported adherence toward COVID-19 prevention guidelines. Three linear regression models were used for data analysis.

RESULTS

A total of 1043 participants responded to the survey, with an average age of 45.3 years, among which 49.61% (n=515) of participants were men, 66.79% (n=696) were White, 11.61% (n=121) were Black or African American, 13.15% (n=137) were Hispanic or Latino, 37.71% (n=382) were Democrat, 30.21% (n=306) were Republican, and 25% (n=260) were not vaccinated. After controlling for covariates, users of TikTok (β=–.29, 95% CI –0.58 to –0.004; P=.047) were associated with lower knowledge of COVID-19 guidelines, users of Instagram (β=–.40, 95% CI –0.68 to –0.12; P=.005) and Twitter (β=–.33, 95% CI –0.58 to –0.08; P=.01) were associated with perceiving guidelines as strict, and users of Facebook (β=–.23, 95% CI –0.42 to –0.043; P=.02) and TikTok (β=–.25, 95% CI –0.5 to -0.009; P=.04) were associated with lower adherence to the guidelines (R2 0.06-0.23).

CONCLUSIONS

These results allude to the complex interactions between online and physical environments. Future interventions should be tailored to subpopulations based on their demographics and social media site use. Efforts to mitigate misinformation and implement digital public health policy must account for the impact of the digital landscape on knowledge, perceptions, and level of adherence toward prevention guidelines for effective pandemic control.
Synthesis of Vanillin-Azine as Colorimetric Chemosensor of Sulfide Anion
Authors: Rokhmah Nevi Faizatu , Mardjan Muhammad Idham Darussalam , Purwono Bambang
Published: December 2022

Vanillin-azine (VA), (4,4'-((1E,1'E)-hydrazine-1,2-diylidenebis(methane-lylidene))bis(2-methoxyphenol) has been synthesized from vanillin and tested as anion colorimetric chemosensors for sulfide anion. The VA was obtained from a condensation reaction between vanillin and hydrazine hydrate with a mol ratio of 2:1 mol for 24 h at room temperature. The structure was elucidated using FTIR, GC-MS, 1H-NMR, and 13C-NMR spectrometers. The VA compound was examined as a colorimetric chemosensor for sulfide anion over several anions of CN−, F−, Cl−, Br−, I−, N3−, CH3COO−, and NO3−. The structure of the product showed agreement with all spectrometric data. The VA chemosensor tests indicated only selective to S2− anion followed by a color change from colorless to light blue in a DMF:HEPES buffer solution (DMF:HBS) medium (9:1, v/v, 10 mM, pH = 7.4). Filter paper strips can detect S2− anion with a color change from white to yellow. The VA chemosensor has a limit of detection (LOD) of 5.4 × 10−4 M, therefore, the VA chemosensor can be applied to detect S2− anion in tap water.
Strategies in Improving Sensitivity of Colorimetry Sensor Based on Silver Nanoparticles in Chemical and Biological Samples
Authors: Badi'ah Hanim Istatik , Ummah Dinda Khoirul , Puspaningsih Ni Nyoman Tri , Supriyanto Ganden
Published: December 2022

Colorimetric sensors-based silver nanoparticles (AgNPs) are very interesting to be studied and developed because of the simplicity and ease in the principle of detection. It does not require sophisticated and affordable tools but still has high sensitivity. The coefficient extinction of AgNPs is relatively higher than AuNPs of the same size, making the sensitivity of AgNPs higher than AuNPs. The principle of detection is based on the aggregation of nanoparticles with analytes that causes shifting in Localized Surface Plasmon Resonance (LSPR) to a larger wavelength, commonly called a bathochromic shift or redshift. It is a favorite phenomenon because it is more easily observed with naked eyes. This sensor shows a good analytic performance with high sensitivity due to strong LSPR and good strategies that selectively bring interaction between analytes and AgNPs. AgNPs are characterized using UV-Visible (Ultra Violet-Visible), TEM (Transmission Electron Microscope), FTIR (Fourier Transform Infrared), and DLS (Dynamic Light Scattering), and many analytes have been detected with this sensor successfully. This article discusses several important parameters in increasing the sensitivity of AgNPs colorimetric sensors. Finally, it can be used as guidelines in the development of methods in the future.
Recent Advances and Future Prospects of Molecular Imprinting Polymers as a Recognition Sensing System for Food Analysis: A Review
Authors: Asaad Abdullah Sfoog Almajed , Abu Bakar Norlaili , Abdul Rahim Nurulsaidah , Wan Mahamod Wan Rusmawati , Hashim Norhayati , Che Soh Siti Kamilah
Published: December 2022

Molecular imprinting polymers (MIPs) have been widely used to produce stable polymeric materials due to their highly selective binding sites to determine the analyte (target molecule) in food products. MIPs begin with a complex compound between the template molecule and the functional monomers that can be polymerized when there is a closely crossed link. MIPs left specific cavities after the removal of templates during washing, which complements the size and shape of the templates. The use of MIPs has contributed to novel advances in materials science, polymer science, natural science, and other multi-disciplinary systems. Optical chemical sensor is an exciting field in MIPs today due to comprehend the unique affirmation limit of associated polymers giving stable polymers with high molecular recognition capabilities. MIPs display a wide extent of relevance, incredible flexibility, security, and high selectivity; their internal affirmation districts can be explicitly gotten together with design molecules to achieve specific affirmation. This review covers the various achievements of sensors used in laboratory analyses. The advancement in the development of MIPs is evaluated with an accentuation on the preparation principle, the discovery process, the molecular recognition mechanism and future perspectives and challenges for MIPs in building an optical chemical sensor.
Structural Elucidation and Antibacterial Activity Studies of Leaf Extracts of Withania somnifera
Authors: Gebeyehu Amsalu Genanaw , Walle Kumlachew Zelalem , Birhanu Meseret ZEbeaman , Gebeyehu Rahel
Published: December 2022

Withania somnifera (W. somnifera), a small, woody shrub in the Solanaceae family, has been studied using a phytochemical test, antibacterial activity and partial characterizations. Air-dried and powdered leaves of the plant were extracted with maceration over an electrical shaker using the solvent chloroform and methanol. After crude extracts of the plant were concentrated, the diffusion antibacterial susceptibility test was carried out on 25, 50, 75, and 100 mg/mL of chloroform and methanol crude extract. The bacteria used were S. aureus, S. pneumonia, E. coli, and S. typhi. Each antibacterial activity test was carried out three times. The most active crude extract of the plant was subjected to a phytochemical test and fractionation with column chromatography. Chloroform and methanol extract of the plant inhibits all cultures of four bacteria. Both chloroform and methanol extract of W. Somnifera inhibits both gram-positive and negative bacterium with a comparable inhibition zone with the standard antibiotics, amoxicillin, gentamicin, and cefoxitine. In addition, it gives a maximum inhibition zone than that of amoxicillin, starting from 25 to 100 mg/mL. Methanol extract of W. somnifera contains phenolic, alkaloids, flavonoids, tannins, and phytosteroids. Partial characterization of pure fractions by using 1H-NMR, 13C-NMR, Dept-135 NMR, and IR spectroscopy, the compound WS-1 affords withaferin A. Withaferine A shows antibacterial activity with an inhibition zone of 11, 10.5, 11, and 9 mm against the bacterium S. aureus, S. pneumoniae, E. coli, and S. typhi respectively.
Tea Waste Products: A New Low-Cost and Green Adsorbent Alternative for Rhodamine-B Dye Removal
Authors: Wulandari Meyliana , Nofrizal Nofrizal , Sulaiman Syed Azhar Syed
Published: December 2022

Tea waste products were thrown out without any intention to utilize their potential benefits. This waste will help to improve industries to absorb rhodamine-B (RhB) dye pollutants currently used by various industries. This study evaluated the application of tea waste products to remove Rh-B from aqueous systems by investigating adsorption kinetics in a batch process. The ability and mechanism of Indonesian black and green tea in RhB adsorption were determined by optimizing temperature, pH, contact time, and concentration of dye solution. Achievement of equilibrium attained at 40 min for black tea (BT) and green tea (GT). Subsequently, the adsorption capacity reached optimum at 80 and 70 °C for GT, and the maximum adsorption capacities for BT and GT were 22 and 47 mg/g, respectively, at pH 2.5. The absorption of RhB in both bio-sorbents was an exothermic process that well fit the Langmuir model and a pseudo-second-order reaction. The presented R2 values from the Langmuir isotherm are 0.9967 (BT) and 0.9979 (GT). The separation factor was determined as 0.026 (BT) and 0.055 (GT). Thermodynamic studies were carried out to calculate free energy, enthalpy, and entropy changes. The result showed that the removal study of BT and GT is 59.06 and 60.25%, respectively, using 10% acetic acid. Study comparisons were carried out on both teas with other bio-sorbents for more improvement. These results show that tea waste products can be used as alternative adsorbents to absorb RhB from wastewater.
Synthesis, Characterization, and Theoretical Study of Novel Charge-Transfer Complexes Derived from 3,4-Selenadiazobenzophenone
Authors: Mohammed Haider Shanshool , Al-Saadawy Nuha Hussain
Published: December 2022

In the current study, a direct method was used to synthesize a new series of charge-transfer complex compounds. Reaction of different quinones with 3,4-selenadiazo benzophenone in a 1:1 mole ratio by acetonitrile gave a unique charge-transfer complex compound in a good yield. All compounds were characterized by UV-Vis, FTIR, 1H-NMR, and 13C-NMR. The analysis findings agreed with the produced compound’s proposed chemical structures. The molecular structure of the produced charge-transfer complex compounds has been investigated using density functional theory. The basis set of 3–21G geometrical designs throughout the geometry optimization, HOMO surfaces, LUMO surfaces, and energy gap has been created. The acceptor and donor have also been studied by comparing the HOMO energies of the charge-transfer complexes. The lower case, electron affinity, ionization potential, electronegativity, and electrophilicity where the total energies of donor-acceptor system and geometric structures demonstrate this structure’s stability. Additionally, the donor-acceptor system has higher reactivity than other systems and larger average polarizability when compared to the donor and acceptor. The findings of this study enable us to choose the kind of bridge that will interact with the donor and acceptor to determine the physical characteristics of the donor-bridge-acceptor.
Analyzing the external auditing and corporate corruption: A case study of family businesses
Authors: Jamil Diyar Abdulmajeed , Mahmood Rozhgar Khorsheed , Ismail Zaid Saad , Jwmaa Swran Jawamir , Younus Saif Qudama , Othman Baban Jabbar , Rashad Muhammed Khazal , Kanabi Idrees Sadeq
Published: December 2022

The failure of several large multinational corporations all over the world has resulted in a heightened interest in the development of suitable procedures that can curb the kinds of actions that might lead to the manipulation of financial reporting. According to the findings of the vast majority of studies, sudden failures of businesses can be traced to sudden alterations in the financial statements of those businesses, which are carried out by the administrations of those businesses and in accordance with their whims. This phenomenon is referred to as "corporate corruption." In addition, there were 94 participants who audited businesses as a part of this study, which was measured using a quantitative research approach. The researcher used a straightforward regression analysis to evaluate how well each of the three research hypotheses held up. According to the findings, the first research hypothesis, which stated that "There is a statistically significant relationship between the general standards of external auditing and corporate corruption practices in family businesses," had the highest value, while the second research hypothesis, which stated that "There is a statistically significant relationship between the general standards of external auditing and corporate corruption practices in family businesses," had the lowest value. The findings revealed that the first research hypothesis, which stated that "there is a statistically significant relationship between general standards of external auditing and corporate corruption practices in family businesses," received the highest value. The findings, however, revealed that the general norms of external auditing play the most beneficial role in minimizing instances of corporate corruption practices in family-owned enterprises.
Mujer Migrante Memorial. La muerte que no cesa
Authors:   UCLA, Zubiaurre María Teresa
Published: December 2022

La autora presenta un recorrido por Mujer Migrante Memorial: A Real and Virtual Installation (Memorial de la Mujer Migrante: Instalación real y virtual—MMM), una instalación artística que tuvo lugar en Junio de 2019 en Venice Beach, California. El objetivo primordial de MMM es servir como homenaje póstumo a las mujeres que salen de sus hogares ya heridas e inician su viaje migratorio para escapar de la violencia, la pobreza y la falta de horizontes de sus países de origen, quienes, trágicamente, no llegan a los Estados Unidos sino para morir muy cerca de la frontera que tanto les costó alcanzar y atravesar. Pero MMM persigue, además, dos propósitos adicionales; busca dar visibilidad a unas muertes ⎯y unas vidas⎯ que la sociedad desaparece de manera sistemática e invita a la reflexión sobre el papel que desempeña el necro-arte, sobre su (presunto) valor como fuerza activadora de conciencias, y sobre los límites que la ética impone a la recreación artística.
Nombrar lo político
Authors:   CIEG-UNAM, Mejía Núñez Gerardo
Published: December 2022

El corpus teórico feminista es un lenguaje político cuyos aportes ⎯entre los que destaca la categoría de análisis género⎯ se han introducido de manera paulatina en el vocabulario científico o académico de varias disciplinas. Así, desde hace tiempo, se ha observado la consolidación de centros de investigación de estudios de género y feministas, y el auge de ofertas de programas académicos que se enmarcan dentro de esta línea investigativa. Asimismo, el discurso de la administración pública recurre cada vez más a la noción de perspectiva de género para el diseño de políticas en todos los niveles y órdenes de gobierno. Pese a esto, este léxico feminista fue tardíamente considerado como parte de la herencia teórica y conceptual del pensamiento político. Este texto, entonces, presenta una breve revisión de ciertos aspectos relacionados con la incorporación de los conceptos género y feminismo a los vocabularios teórico-analíticos de campos de estudio como la filosofía, teoría y ciencia política.
Pedagogías feministas y sus encuentros afectantes. Con los pies en la tierra, las manos en la masa y la escuela patas arriba
Authors:   CIEG-UNAM, Piñones Vázquez Patricia
Published: December 2022

En este ensayo se presentan algunas reflexiones, experiencias y propuestas en torno a la práctica pedagógica aplicada en múltiples espacios educativos. Sin dejar de lado el contexto coyuntural del activismo feminista actual ―en especial de aquellos movimientos que se desarrollan dentro de la Facultad de Filosofía y Letras de la unam―, se expone la importancia que tienen la construcción colectiva de conocimiento, la colectivización de los saberes y los encuentros afectantes en la aventura de enseñar-aprender La autora propone estrategias que permitan el surgimiento de ensayos performáticos para convertir el aula en un espacio abierto a la polifonía y lo polirrítmico, un espacio de libertad, esperanza, asamblea y danza. Estas pedagogías pretenden motivar una transformación social y cultural, propiciada por el desarrollo de la reflexión y el pensamiento críticos que, primero, se ensayan en las aulas y después ayudan a la construcción de conocimientos fuera de estas.
Frame Design and Analysis of Electric Formula One Car: A Review
Authors: Shelke Prof. M. S. , Umare Arpit , Bhongade Kunal , Ambade Krutika , Jiwane Payal
Published: December 2022

Abstract: The aim is to design and analysis of a chassis. A chassis design involves selecting optimum measures of parts and iterating it to achieve the objectives assumed. Every part of chassis is related to each other; it is necessary to study effects to get optimum design. Mild steel is a ferrous metal made from iron and carbon. Various formulas were used and we have to satisfies all the objectives in the beginning.
Search Engine Optimization with Google
Authors: Goyal Harsh , kapoor Komal
Published: December 2022

Abstract: This paper is a finished survey that how various strategies of Search Engine Optimization (SEO) can help to improve product marketing. Search engines have now become an important channel for increasing SMEs’ global reach and helps companies to compete with other and large companies. SMEs are using search engine optimization to improve their online visibility as a result (SEO). With the help of Search Engine Optimization small companies can actually now compete with the large companies and can appear ahead of large. The main objective of every website to list at the top of all thelinks on search engines. So, search engine optimization is an art which helps to improves a website’s visibility in the search engine results. Search engines makes the business environment more transparent and more competitive. For data collection used literature survey. The findings of this study show that using an SEO strategy can significantly enhance product marketing.
Investigación forense digital en entidades del Estado colombiano: acercamiento a la Ley 1952 de 2019
Authors: Vargas Montoya Héctor Fernando , Solano Oviedo Darling Stella , Roldán Alvarez Miguel Angel
Published: December 2022

Cuando se está en frente de un posible delito informático o una falta disciplinaria en donde se ha usado un medio digital (como medio o como fin) y que es objeto de investigación, se requiere de diferentes procedimientos para lograr hallar el qué, cómo, quién y cuándo sucedió el posible hecho punible o falta disciplinaria. Este artículo tiene como objetivo proponer un diseño de una metodología para el desarrollo de una investigación forense digital, para ello, el método utilizado fue hacer uso de procesos y métodos aceptados por la comunidad internacional, así como la adecuada gestión y tratamiento de la evidencia digital (cadena de custodia), de forma que sirva como una herramienta técnica de apoyo para procesos administrativos y disciplinarios que adelante una entidad del Estado colombiano en el marco de la Ley 1952 de 2019. Como resultado, se cuenta con una propuesta que puede ser usada para la aplicación del Código General Disciplinario en cuanto a la obtención de pruebas digitales, con lo cual, se concluye que los diferentes investigadores tienen a disposición una metodología que puede llevar resultados óptimos, con ello dar cumplimiento a la ley.
Image Analysis as the Means of Cultural Representation Study in a Worldview
Authors: Balandina Ekaterina S. , Peredrienko Tatiana Yu.
Published: December 2022

The purpose of the article is to present the methodology of image analysis as the means of cultural representation study in a worldview on the example of the image “work”. The research is based on the idea that any phenomena of reality perceived by a person in the process of activity and communication are revealed in his mind through images. These images record not only causal and spatial relationships of phenomena and emotions in the process of perception, but also can be characterized by a certain social and ethno-cultural peculiarities, dynamism and variability. The images connected with real-world objects are studied through the mixed methods research including the associative experiment and gradual scaling. Associative fields constructed in the course of the experiment allow analyzing images from linguistic and psycholinguistic points of view according to the formalgrammatical features of the received responses, contiguity - similarity classification, and semantic field grouping. The experiment was organised between the equal number of Russian, Chinese and Arabic students of 20-25 years old. The interest to study this age group is explained by the fact that it is young people who form the future of any country and society in general. To study the perception of the image “work” the respondents were asked to fulfill the questionnaires in their native languages where they were to write the first association that came to their mind when they saw the word-stimulus. All responses presented in the article were translated into the English language. In conclusion, the authors summarise the received results, describe the complex structure of various associative pairs, and identify differences and similarities in the perception of the studied image in worldviews of various culture representatives.
The Image of Soviet Russia in the Short Poems and Poems of the Turkish Poet Nazim Hikmet Ran
Authors: Dogan Merve G.
Published: December 2022

The article is devoted to the study of short poems and poems by the Turkish poet Nazim Hikmet Ran (1902-1963), reflecting the images of Soviet Russia. The article analyzes the frames and subframes that construct the image of Soviet Russia; studies the specificity of the realities of Russian culture; analyzes the observations, ideas and impressions of the Turkish poet about the way of life in Russia in the first half of the 20th century; reveals the correlation of the image of Soviet Russia created by the Turkish poet with the archetypes of Soviet Russia in the works of Nazim Hikmet Ran. The purpose of this article is to identify the languacultural specifity of the image of Soviet Russia in the work of Nazim Hikmet Ran. The material for the study was short poems and poems written by the poet during his stay in the USSR in 1921-1930. The research methods of this article are semantic analysis, linguacultural analysis, complex analysis, observation method. As a result of the analysis of the texts of short poems and poems, frames and subframes that construct the image of Soviet Russia in the poetic picture of the world of the Turkish poet are revealed.
The Second Language Acquisition: System of Extended Integrative Control for Linguistic Knowledges and Communication Skills Sustainability
Authors: Anikina Marina N.
Published: December 2022

The article is devoted to the search for new approaches and forms of control over the assimilation of students’ knowledge at the initial stage within the framework of a worldview approach to teaching Russian as a foreign language. Based on the analysis of existing forms and types of control, a conclusion was made about their incomplete compliance with the goals of teaching live communication in Russian. The main problem is the lack of motivation to form an oral or written statement. The thematic principle for the organization of control over the assimilation of listening / speaking skills is outdated, it does not reflect the specifics of modern interpersonal communication, including socially conditioned one. Based on this conclusion, the article outlines approaches to the creation of an expanded comprehensive control system aimed, on the one hand, at testing (control) skills of free communication, and, on the other hand, at psychological stimulation (psychological boost) of communication.
Working with Media Text in the Audience: Case Method
Authors: Dianova Lyudmila P.
Published: December 2022

This article proposes a holistic approach to text analysis as an object of linguistic research and pedagogical process. The purpose of the work is to demonstrate a methodology for working with a textual whole, which would be universal for both foreign students and students of Russian universities. Within the framework of the proposed concept, such concepts as discourse, media text, creolization are put forward, which indicates that the educational process is now immersed in a new semiotic reality that needs to be taken into account. We examined the methodology of working with media text in the audience. It is universal in nature and can be applied to the widest textual material. By examining the text in its many aspects, we let students understand how discursive its nature is. The text, as our case shows, is not just an intermediary between communicants. This is a synergistic reality, which is modeled by the intentions of one communicator and the peculiarities of perception of another. Our main task was to acquaint students with the features of the text as an element of discourse, as well as to learn how to work thoughtfully with its conceptual field. SEO analysis and cognitive mapping were considered as methods of working with text.
Sentinel Lymph Node Biopsy Based on Anatomical Landmarks and Locoregional Mapping of Inguinofemoral Sentinel Lymph Nodes in Women with Vulval Cancer: an Operative Technique.
Authors: Kwong Audrey , Scerif Miski , Yap Jason
Published: December 2022

Inguinal lymph node involvement is the most robust predictor of
mortality in women with vulval cancer and sentinel lymph node biopsy is
recognised as a safe diagnostic modality provided strict patient
criteria as defined by the GROINSS-V study are respected. Studies have
largely concentrated on the efficacy of different intraoperative
detection modalities or histopathological protocols whilst the
literature describing a standardised surgical technique remains
deficient. We hereby propose a reproducible operative technique based on
anatomical landmarks and an appreciation of the territorial mapping of
inguinal sentinel lymph nodes.
Durable and Dramatic Response to Checkpoint Inhibition Combined with IDO1 Inhibitor Celecoxib in a Patient with p16+ Metastatic Sinonasal Undifferentiated Carcinoma
Authors: Trinh Jonathan , Tan Alan
Published: December 2022

Background: Sinonasal undifferentiated carcinoma (SNUC) is an
exceedingly rare head and neck malignancy. No consensus exists on
treatment for metastatic disease. Case: A 56-year-old female was
diagnosed with SNUC after endorsing sinus congestion, diplopia, and
right orbital pain. Initially treated with surgery and radiation, she
later developed significant metastatic disease. She demonstrated
progression of her hepatic metastases under pembrolizumab therapy.
However, the addition of ipilimumab and an IDO1 inhibitor resulted in
significant improvement in her lesions as well as an ongoing durable
response. Her regimen was complicated by immune-related adverse events
successfully treated with steroids. Conclusion: Dual checkpoint
inhibition deserves consideration when treating metastatic SNUC,
especially after single agent therapy has failed. The positive effect of
this treatment may be augmented by IDO1 inhibition.
Test method for vapor collection and ion mobility detection of explosives with low vapor pressure
Authors: Choi Sung-Seen , Son Chae Eun , Choi He-Ryun
Published: December 2022

Rationale: IMS has been widely used for the on-site detection of
explosives. Air sampling method is applicable only when the
concentration of explosive vapor is considerably high in the air, but
vapor pressures of common explosives such as TNT, RDX, and PETN are very
low. A test method for analyzing the vapor detection efficiency of
explosives with low vapor pressure via IMS was developed using
artificial vapor and collection matrices. Methods: Artificial explosive
vapor was produced by spraying an explosive solution in acetone. Fifteen
collection matrices of various materials with woven or nonwoven
structure were tested. Two arrangements of horizontal and vertical
positions of the collection matrices were employed. Explosive vapor
collected in the matrix was analyzed through IMS. Results: Only three
collection matrices of stainless steel mesh (SSM),
polytetrafluoroethylene sheet (PFS), and lens cleansing paper (LCP)
showed the TNT and/or RDX ion peaks at explosive vapor concentration of
49 ng/L. There was no collection matrix to detect PETN vapor at lower
than 49 ng/L. For the PFS, TNT and RDX were detected at 49 ng/L vapor
concentration. For the LCP, TNT and RDX were detected at vapor
concentrations of 14 and 49 ng/L, irrespectively. Conclusions: The
difference in the explosive vapor detection efficiencies could be
explained by the adsorption and desorption capabilities of the
collection matrices. The proposed method can be used for evaluating the
vapor detection efficiency of hazardous materials with low vapor
pressure.
Solar wind modeling with the Alfvén Wave Solar atmosphere Model driven by HMI-based Near-Real-Time maps by the National Solar Observatory
Authors: Sachdeva Nishtha , Manchester Ward B , Sokolov Igor , Huang Zhenguang , Pevtsov Alexander , Bertello Luca , Pevtsov Alexei A , Toth Gabor , Holst Bart Van Der
Published: December 2022

We explore model performance for the Alfvén Wave Solar atmosphere Model
(AWSoM) with near-9 real-time (NRT) synoptic maps of the photospheric
vector magnetic field. These maps, produced by 10 assimilating data from
the Helioseismic Magnetic Imager (HMI) onboard the Solar Dynamics
Obser-11 vatory (SDO), use a different method developed at the National
Solar Observatory (NSO) to provide 12 a near contemporaneous source of
data to drive numerical models. Here, we apply these NSO-HMI-13 NRT maps
to simulate three Carrington rotations (CRs): 2107-2108 (centered on
2011/03/07 20:12 14 CME event), 2123 (integer CR) and 2218-2219
(centered on 2019/07/2 solar eclipse), which together 15 cover a wide
range of activity level for solar cycle 24. We show simulation results,
which reproduce 16 both extreme ultraviolet emission (EUV) from the low
corona while simultaneously matching in situ 17 observations at 1 au as
well as quantify the total unsigned open magnetic flux from these maps.
18
Fuzzy optimization model of two parameter Weibull deteriorating rate with quadratic demand and variable holding cost under allowable shortages
Authors: Poswal Preety , Chauhan Anand , Rajoria Yogendra , Boadh Rahul , Goel Abhinav
Published: December 2022

In this paper, a fuzzy inventory model with a Weibull deterioration rate, a
quadratic demand rate, and a variable holding cost under permissible
shortages has been developed. The deterioration rate is expressed by a
two-parameter Weibull distribution. During a shortage, some buyers wait for
the actual product, while others do not. This shortfall is considered
partially backlogged in this model. Some buyers wait for the actual product
during such shortages, but many do not. Therefore, partially backlogged
shortages are taken into account in this approach. In a traditional
inventory model, all parameters such as purchasing cost, shortage cost,
holding cost, etc. are predetermined. However, there will be some
variations. As a result, fuzzy factors are more accurate to deal with the
real world?s problems. This research attempts to cut down the cost in a
fuzzy environment by using quadratic demand, shortage, Weibull deterioration
rate, and variable holding cost. Costs such as ordering, shortage, and
deterioration are addressed as pentagonal fuzzy numbers that are defuzzified
using a graded mean representation approach. Finally, sensitivity analysis
was carried out to investigate the influence of cost parameters on total
inventory cost. A numerical example is used to validate the proposed model
in a real-world system.
Mathematical model for analysing availability of threshing combine machine under reduced capacity
Authors: Singla Shakuntla , Modibbo Umar , Mijinyawa Mohammed , Malik Subhash , Verma Shubham , Khurana Pooja
Published: December 2022

Obtaining system availability in an engineering design is trickish and
challenging, especially when there is a reduction in capacity; however, it
supports system maintainability. In this paper, a mathematical model for
finding the availability under the reduced capacity has been proposed using
the Chapman Kolmogorov approach with the help of transition diagrams
associated with various possible combinations of probabilities. The paper
observes the most critical subsystem by selecting variable failure and
repair rates from different subsystems. It deals with the sensitivity
analysis of a complex repairable threshing combined machine comprising
subsystems in a series configuration and the threshing machine consisting of
21 subsystems. The device works in total capacity when the threshing drum
and feeding Hooper work in the complete state, and the concave subsystem and
blower work with reduced power. This study dealt with uncertain data and was
analyzed analytically using a complex repairable system. The availability of
the entire machine has been investigated analytically, and various
availability indices such as subsystems extruder have been computed and
reported. The study discovered that subsystem extruder has the most impact
on some subsystems? overall system availability.
Feasibility and Safety of a Powered Exoskeleton for Balance Training for People Living with Multiple Sclerosis: A Single-Group Preliminary Study (Rapper III)
Authors: Sakel Mohamed , Saunders Karen , Hodgson Philip , Stephensen David , Phadke Chetan P. , Bassett Paul A. , Wilkinson David
Published: December 2022

Objective: To evaluate the feasibility, usability, safety, and potential health benefits of using an exoskeleton device for rehabilitation of people living with multiple sclerosis.Design: Single-group preliminary study.Subjects: Eleven adults living with multiple sclerosis, with Expanded Disability Status Scores that ranged from 6 to 7.5 (mean age (standard deviation; SD) 54.2 (11.8) years), were recruited.Methods: Individual participants undertook a balance rehabilitation exercise programme using the Rex Rehab robotic exoskeleton device. Each participant undertook 4 × 45–60 min supervised, balance exercise sessions. Primary outcomes were: (i) the number of participants who completed the trial protocol safely, and (ii) the number and nature of adverse events reported. Secondary outcomes were: mobility; balance; spasticity; sleep; functional independence; quality of life; and device satisfaction.Results: Ten out of 11 participants completed the trial protocol safely. Four adverse events were recorded (1 serious), all of which were deemed unrelated to the trial. Secondary outcomes showed allied improvements in balance, joint mobility, spasticity and quality of life. All participants found the device acceptable to use.Conclusion: These results suggest that it is feasible and safe to use the Rex Rehab exoskeleton device to assist with balance rehabilitation for people living with multiple sclerosis.
LAY ABSTRACTMultiple sclerosis (MS) is a chronic neurological disease that can lead to symptoms, including muscle weakness and balance issues. The incidence of falls in people living with MS (PwMS) is 3 times higher than that in older people. To try to reduce this vulnerability to falls, this study aimed to evaluate the feasibility, safety, and potential health benefits of using an exoskeleton device for a balance exercise programme. Eleven PwMS undertook 4×45–60 min supervised, balance exercise sessions using the exoskeleton device. Feasibility and safety were assessed by identifying the number of participants who completed the trial safely; consideration of any issues experienced during the trial and how these were resolved. Ten participants completed the trial (1 withdrew due to their MS) and only 4 issues were reported, all of which were unrelated to the trial. Some participants also experienced improvements in balance, mobility, and quality of life.
Plants That Can be Used as Plant-Based Edible Vaccines; Current Situation and Recent Developments
Authors: İsmail Karakaş
Published: December 2022

Among the purposes of genetic engineering technology applications in plants, improving product quality, increasing resistance to harmful organisms and improving agronomic properties, the most important one is the production of drugs, hormones and vaccines for humans and animals (for example, the use of potatoes in cholera vaccines). Today, the use of plants as bioreactors to obtain recombinant proteins from plants has been further developed and accelerated thanks to the developments in plant genetics, molecular biology and biotechnology. Appearing as a concept about a decade ago, plant bioreactors are genetically modified plants whose genomes have been manipulated to incorporate and express gene sequences of a number of useful proteins from different biological sources. Plant-derived bioreactor systems offer significant advantages over techniques used for other biological-based protein production. Easy and inexpensive production from plant tissues, providing appropriate post-translational modifications for the production of recombinant viral and bacterial antigens, and showing similar biological activity to recombinant vaccines obtained in microorganisms are important reasons that encourage the use of plant tissues in vaccine production. Edible vaccines, which create an immune response in the body against a foreign pathogen that causes disease, have a working mechanism that serves as both a nutritive and a vaccine that we consume in our daily lives. In the development of edible vaccines, the gene responsible for the production of the part of the foreign pathogen that causes the disease, that is, the antigen, which provides the immune response in the body, is transferred to the plants. With this technique, antigen production is carried out in plants. For example, thanks to today's advancing technology, enough hepatitis B antigens to vaccinate all of the world's approximately 133 million live births each year can be grown on a field of approximately two hundred hectares. In addition to these, edible vaccine technology also makes edible vaccines an interesting concept as secondgeneration vaccines, as they allow several antigens to approach M (microcoat) cells at the same time, by offering multicomponent vaccine proteins that are possible by crossing two plant lines.
Classroom Management Strategies among Basic School Teachers: Toward Holistic Teacher Education
Authors: Owusu-Addo Augustine
Published: December 2022

There have been cases when students depict unacceptable behavior traits, which need to be managed by teachers during instructional hours. Using Wolfgang and Glickman Teacher’s Behavior Continuum as the theoretical framework, this study reports classroom management strategies among basic schoolteachers and their implications for teacher education in Ghana. Descriptive research design and a quantitative approach were used; questionnaire was used to gather data from the respondents. One hundred and five (105) teachers were selected using simple random sampling technique. Validity and reliability of the research instrument were tested using expert judgement and Cronbach’s alpha, respectively. Descriptive statistics (means and standard deviations) were used in the analyses of the research questions. The findings were that the majority of teachers used a teacher-centered approach. It was also discovered that teachers had difficulty in managing some disruptive student behaviors, as the most prevalent disruptive behavior exhibited by students was noise making. Some teachers also agreed that once the classroom environment is conducive, it makes teaching easier because the teacher gets the full attention and concentration of students. Teachers should set example for students by acting appropriately at all times; especially, in the classroom. It was recommended, among other things, that teachers pay extra attention to the special needs of students and encourage them to behave in the classroom. While holistic education is governed by a single underlying principle, teachers need to use a variety of approaches and strategies to foster a holistic learning culture.
Professores de Enfermagem: obstáculos que limitam o valor formativo da prática clínica
Authors:   Escola Superior de Saúde Ribeiro Sanches, Longo João , Moutinho Lídia ,   Escola Superior de Saúde Ribeiro Sanches
Published: December 2022

O presente artigo tem como propósito responder à questão: quais os principais obstáculos sentidos pelos professores em contexto de prática clínica na formação inicial em enfermagem? e ao objetivo: compreender em que medida esses obstáculos podem ser condicionantes do desenvolvimento profissional docente. Trata-se de um estudo de abordagem qualitativa, descritiva de natureza interpretativa. A amostra é intencional, composta por sessenta e oito professores de treze Escolas Superiores Saúde | Enfermagem portuguesas. A recolha de dados foi efetuada através da técnica de focus-group e o tratamento de dados foi executado com recurso à análise de conteúdo temática segundo Bardin. No decurso do processo investigativo, foram cumpridas as recomendações dos padrões exigidos pela Declaração de Helsínquia e Convenção de Oviedo. Todos os participantes foram informados sobre o estudo e seus objetivos, assim como sobre a garantia de confidencialidade dos seus dados e direito de abandonar o estudo em qualquer momento. Os resultados mostram que os obstáculos sentidos pelos professores durante os períodos de ensino clínico aparentam estar relacionados com a falta de preparação para a função supervisiva; dificuldades de interação com os atores envolvidos no processo formativo (supervisor clínico e estudante), ausência de articulação entre a academia e os contextos profissionais e, ainda, com o modo como os ensinos clínicos são organizados.
Geomorphology of the Guacimal River catchment, Costa Rica
Authors: Quesada-Román Adolfo
Published: December 2022

The Guacimal River catchment has an area of 181 km2 and is located in the NW of Costa Rica, between the coordinates 84.745° W-10.016° N and 84.909° W-10.325° N. In this territory, as in most of the country, detailed geomorphological studies are scarce; therefore, the objective of this paper is to present the geomorphological mapping at a scale of 1:25,000 of the Guacimal River, which allows us to explain the dynamics of the agents involved in the modeling of the catchment. The work methodology consisted of three stages: pre-mapping, field activity and post-mapping, which resulted in a map in which ten relief forms are represented, ordered according to their morphogenesis in endogenous modeled and exogenous (fluvial, gravitational and littoral). This document will be the base line for land use planning, both continental and coastal, and for local risk management.
Arte revulsivo contra la turistificación
Authors: Garcia-Jimenez Maria del Mar
Published: December 2022

La turistificación rápida e intensa surgió como parte de un fenómeno global anterior al estallido del coronavirus SARS-CoV-2, atrapando a destinos turísticos mundiales consolidados y emergentes. Sus ramificaciones perturbaron la tranquilidad de unos lugareños que se vieron enfrentados a diversos desafíos como la pérdida identitaria, la desigualdad social y el vaciado demográfico de los centros de las ciudades. El potencial subversivo de las prácticas híbridas que vinculan al arte con el activismo asumió su compromiso social ante las problemáticas y reivindicaciones surgidas de un modelo de desplazamientos turísticos sobredimensionado. En este artículo se exploran estudios de casos descriptivos que, en sus respectivos espacios de producción transcultural, tienen en común una perspectiva crítica ante el modelo vacacional referido. Específicamente, aborda los perfiles de trabajo y las reflexiones sensibilizadoras de Left Hand Rotation en Lisboa, Banksy en Venecia y Alejandro Villén en Málaga, así como a la muestra colectiva Alicántropo en Alicante.