bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Age on Cervical Vestibular Evoked Myogenic Potentials and Ocular Vestibular Evoked Myogenic Potentials Using 750 Hz Tone Burst Stimuli among Healthy Adults
Authors:   Audiology Program, Centre for Rehabilitation and Special Needs Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia, Sayed Sharifah Zainon , Abdul Wahat Nor Haniza ,   Audiology Program, Centre for Rehabilitation and Special Needs Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
Published: August 2022

Background: The vestibular evoked myogenic potentials (VEMPs) response characteristics depend on age, stimulus and individual anatomical differences. Therefore, normative data are required for accurate VEMPs interpretations. This cross-sectional study investigates VEMPs age-related changes among healthy adults using 750 Hz short alternating tone burst (TB) stimuli. Methods: Fifty adults aged between 23 years old and 76 years old with a mean of 51.56 (SD = 16.44) years old underwent air-conducted (AC) cervical VEMP (cVEMP) and head taps ocular VEMPs (oVEMPs) testing. Results: The cVEMPs and oVEMPs response rates reduced significantly at the age of 50-year-old and above. No significant age trends were observed for both cVEMPs and oVEMPs latencies and asymmetry ratios. However, amplitude reduced with increasing age for both cVEMPs, P < 0.001 and oVEMPs, P = 0.01. No significant differences in cVEMPs and oVEMPs latencies, amplitude or asymmetry ratios were identified between gender. Conclusion: To the best of our knowledge, this is the first published normative data for cVEMPs and oVEMPS in Malaysia and Southeast Asia, obtained among healthy adults aged between 23 years old and 76 years old. Health professionals in the region can use these findings as VEMPs normative references in their clinical settings.
Histopathological Correlation of Breast Carcinoma with Breast Imaging-Reporting and Data System
Authors:   Department of Radiology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia, Aziz Suraya , Mohamad Muhammad Afiq ,   Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia, Md Zin Reena Rahayu ,   Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia
Published: August 2022

Background: Breast cancer is one of the commonest malignancy cancer worldwide and the Breast Imaging-Reporting and Data System (BI-RADS) classification has been extensively utilised as an adjunct to histopathological examination for malignant breast diseases. This study aims to analyse the concordance between radiological and histopathological findings, demonstrate the high predictive value in the BI-RADS category and evaluate the impact of these findings on surgical intervention and treatment outcome. Methods: This is a single-centre retrospective study, analysing patients who underwent radiological examination with BI-RADS categories 3, 4 and 5 followed by histopathological examination confirming the diagnosis based on breast core biopsy or excision specimen over 3 years. Results: A total of 316 specimens from 310 patients were included in this study; 75 cases were categorised BI-RADS 3, 166 as BI-RADS 4 and 75 as BI-RADS 5. Of these, 66 (20.8%) patients in BI-RADS category 3, 82 (25.9%) in BI-RADS category 4 and 5 (1.6%) in BI-RADS category 5 were reported as benign on histopathological examination. Malignant cases were reported in nine (2.8%) cases in BI-RADS category 3, 84 (26.6%) in BI-RADS category 4 and 70 (22.2%) in BI- RADS category 5. The positive predictive value (PPV), negative predictive value (NPV), sensitivity and specificity were 63.9%, 88%, 94.48%, and 43.14%, respectively. Conclusion: There is a significant correlation between BI-RADS score and histopathological results of breast cancer. A higher BI-RADS score is associated with a higher possibility of malignancy (P < 0.001). Our institution’s performance is comparable to other previously published data.
Amazonian Fruit Mari-Mari (Cassia leiandra Benth.): Identification of Flavonoids and Antioxidant, Antimicrobial and Antiproliferative Properties
Authors: de Souza Mayane , Sá Ingrity Suelen , de Freitas Flávio Augusto , de Souza Afonso , Nunomura Sergio , Muniz Magno , Pereira Ana Paula , Augusto Bianca , Gomes Giovana , Perdomo Renata , Macedo Maria Lígia , Weber Simone , Nunomura Rita de Cassia
Published: August 2022

Mari-mari (Cassia leiandra Benth.) is an Amazonian native fruit that is highly appreciated in the northern region of Brazil, but there are few studies regarding its chemical composition and/or biological properties. A phytochemical study was conducted on the extracts of the pulp, peel and seeds; and their antioxidant, cytotoxic and antimicrobial potential were also determined. Methanol and acetone extracts from different fruit parts were subjected to total phenolic, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and FeIII reducing capacity (FRAP) assays. From the peel extracts, the engeletin and astilbin could also be isolated and characterized based on nuclear magnetic resonance spectroscopy and high-resolution mass spectrometry. A quantification using ultra-fast liquid chromatography of acetone dry crude extracts (DCE) of the peel showed that engeletin was the main compound (532.77 mg g-1 DCE). Astilbin content was also determined (131.53 mg g-1 DCE). The antibacterial and antiproliferative activities were evaluated and the methanol extract of the peel showed higher growth inhibition activity against all tested bacteria. Engeletin showed a relevant antimicrobial effect against Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coli. Acetone and methanol peel extracts exhibited a relevant inhibitory effect on the proliferation of breast carcinoma cells (MCF-7), with no toxicity to the normal cell line (NIH/3T3).
Comprehensive evaluation and scenario simulation of carrying capacity of water resources in Mu Us Sandy Land, China
Authors: Liu Luyao , Xu Xue , Wu Jiaru , Jarvie Scott , Li Fengshi , Han Peng , Zhang Qing
Published: August 2022

With the rapid improvement in socioeconomic conditions globally, the demand for water resources has dramatically increased. Evaluating water resource carrying capacity (WRCC) is crucial for regional sustainable development. To date, limited attention has been paid to WRCC in areas of predominantly sandy land, with the impact of vegetation restoration in ecologically degraded areas on WRCC remaining unclear. In this study, using a comprehensive evaluation index and a system dynamics model, we evaluated the WRCC of the Mu Us Sandy Land, Inner Mongolia, China, from 2000 to 2019 then projected to 2030. Our results show WRCC has decreased since 2000, reaching a general state by 2019. In a future scenario where historical development remains unabated, WRCC will continue to decline to a poor carrying state by 2030. The comprehensive scheme based on industrial restructuring and water conservation performed the best in terms of WRCC, continuously increasing and returning to a general carrying state by 2030. Our findings highlight the WRCC of the Mu Us Sandy Land is not optimistic and subsequent ecological restoration should proceed with caution. A comprehensive scheme is an optimal development strategy for the future.
Multi-objective water resources optimum allocation scheme based on an improved standard cuckoo search algorithm (ISCSA)
Authors: Zhou Ke
Published: August 2022

The standard cuckoo search algorithm (SCSA) is an intelligent population optimization algorithm, which is also a heuristic search algorithm. The advantages of the SCSA (such as its convenient operation, heuristic searching, etc.) make it easy to find an optimal solution and maintain a wide searching range. However, the SCSA also has some drawbacks, such as long searching time, and the ease of falling on a local optimum. In order to solve the problems existing with SCSA, in this paper, an improved standard cuckoo search algorithm (ISCSA) was studied, which includes chaotic initialization and a Gaussian disturbance algorithm. As a case study, taking economic, social and ecological benefits as the objective function, multi-objective water resources optimal allocation models were constructed in Xianxiang Region, China. The ISCSA was applied to solve the water allocation models and a multi-objective optimal water supply scheme for Xinxiang region was obtained. Water resources optimal allocation schemes for the planning level year (2025) for 12 water supply sub-regions were predicted. A desirable eco-environment and other benefits were achieved using the studied methods. The results show that the ISCSA has obvious advantages in the solution of water resources optimal allocation and planning.
Green complexation for heavy metals removal from wastewater by Keggin-polyoxometalates enhanced ultrafiltration
Authors: Kahloul Malak , Mahfoudhi Selim , Ounifi Ibtissem , Elabed Badra , Amor Taissire Ben , Hafiane Amor
Published: August 2022

The presence of heavy metals in wastewater has become a serious issue and a global concern for the environment and public health with rapid progress of modern textile industry. To minimize the health risks of heavy metals their complexation to a chelating agent constitute a promising process using membrane separation. We highlight for the first time the use of Keggin type-polyoxometalates (PW12) as complexing agent to eliminate heavy metals from synthetic textile wastewater. Indeed, filtration experiments were performed through the ultrafiltration organic regenerated cellulose membrane (3KDa). Effects of pressure (1–2.5 bar), PW12 concentration (10–50 mg·L−1), salt concentration (10−4–2 M) and pH value (2–12) on cadmium (Cd) and copper (Cu) removal were regularly explored. Experimental data showed that the addition of PW12 improves metal removal efficiency (up to 90%). The addition of NaCl salt significantly decreases the metals retention to 42%. The retention drop is probably due to the competition between Na+ and metals on complexation same negative sites of the PW12 and to the electric double-layer compressing. 24 full factorial design has been used to evaluate the most influencing parameters. The results obtained revealed that the maximum metal retention was 99% for both Cd and Cu.
Biologically Active 2-Oxazolidinone Derivatives Beyond Antibacterial
Activities
Authors: Yuan Leer , Sheng Rong , Guan Mengying , Wang Yuan , Chen Siyuan
Published: August 2022

2-Oxazolidinone is well known as a pharmacophore for antibacterial agents
represented by two marketed medicines, Linezolid and Tedizolid. On the other hand,
there are growing reports on the various biological activities of 2-oxazolidinones beyond
antibacterial activities. Therefore, in this review, we provide an overview of the progress
of this untraditional area of 2-oxazolidinones in the past 10 years (2011-2021).
Detection of Ningnanmycin Using Fluorescence Spectroscopy Combined
with BP Neural Network
Authors: Wang Xiaoyan , Jiang Zhezhen , Ji Rendong , Han Yue , Bian Haiyi , Yang Yudong , Feng Xiaotao , Xu Jiangyu , Wang Mengyuan
Published: August 2022

Background:

Ningnanmycin is a new antibiotic pesticide with good bactericidal and
antiviral efficacy, which is widely used in the control of fruit and vegetable diseases, and the excessive
pesticide residues pose a serious threat to the environment and human health.

Methods:

In this study, we used fluorescence spectrometer to scan the three-dimensional spectrum
of ningnanmycin samples. We used a BP neural network to complete the regression analysis of content
prediction based on the fluorescence spectra. After that, the prediction performance of the BP
neural network was compared with the exponential fitting method.

Results:

The results of the BP neural network modeling based on the obtained samples showed that
the mean square error of the prediction results of the test set is less than 10-4, the R-square is greater
than 0.99, the average recovery is 99.11%, and the model performance of the BP neural network is
better than exponential fitting.

Conclusion:

Studies have shown that fluorescence spectroscopy combined with BP neural network
can effectively predict the concentration of ningnanmycin.
SHR6390 Combined with Cabozantinib Inhibits Tumor Progression in the
Hepatocellular Carcinoma Mouse Model
Authors: Liu Caiqi , Shi Jiaqi , Lin Binlin , Zhou Meng , Shan Dan , Nie Jianhua , Wang Yan , Zhang Yanqiao , Han Peng , Zheng Tongsen
Published: August 2022

Background:

A novel CDK4/6 inhibitor SHR6390 has shown significant anti-tumor effects.
However, its role in hepatocellular carcinoma (HCC) remains unknown.

Objective:

To explore the inhibitory effect of combination treatment with SHR6390 and cabozantinib
in HCC, and its antitumor mechanism, so as to provide a more effective therapeutic strategy for HCC
patients.

Methods:

We investigated SHR6390, monotherapy or combined with cabozantinib, by CCK8, wound
healing, transwell, western blotting, immunohistochemistry and mouse model of a subcutaneous tumor.

Results:

Our results show that SHR6390 exhibited potent anti-proliferative activity against HCC in a
dose-dependent manner. SHR6390 combined with cabozantinib exhibited more potent inhibition of
cell viability, migration and invasion. In terms of potential mechanisms, we found that cabozantinib
could lead to phosphorylation of Rb, which was reduced in SHR6390 and combined groups. SHR6390
monotherapy inhibited the growth of subcutaneous HCC tumors, besides, the combination treatment
with SHR6390 and cabozantinib exerted synergistic anti-tumor activity in vivo.

Conclusion:

SHR6390 is effective against HCC, monotherapy or combined with cabozantinib.
Internuclear Ophthalmoplegia as an Isolated Symptom of Brainstem
Wake-up Stroke Responsive to Intravenous Thrombolysis: Evidence from
MRI
Authors: Barbagallo Gaetano , Caggiula Marcella , Rizzo Annalisa , Direnzo Vita , Lupo Angela , Fasano Antonio , Greco Cosimo Angelo , Pauciulo Alfredo , Saponaro Antonio , Paladini Adriana , Barbarini Leonardo
Published: August 2022

Background:

Internuclear ophthalmoplegia (INO) is a disorder of eye movements caused
by a lesion involving the medial longitudinal fasciculus (MLF) within the brainstem, and it is characterized
by adduction impairment combined with contralateral dissociated abduction nystagmus. The
frequency of acute ischemic stroke (AIS) presenting with INO as a predominant symptom is very low,
and many patients suffering from this brainstem AIS are precluded from intravenous thrombolysis
(IVT).

Objective:

To provide for the first time a magnetic resonance imaging (MRI) evidence of response to
the IVT in brainstem wake-up stroke presenting with INO as an isolated symptom.

Methods:

Here, we described a rare case of pons AIS presenting with INO as a unique symptom of
awakening. In order to differentiate an ischemic stroke from other stroke mimics, and to determine
whether the patient was within the therapeutic window for IVT (wake-up stroke), brain MRI including
DWI and FLAIR sequences was acquired.

Results:

A left paramedian pontine DWI/FLAIR mismatch was detected and the patient was considered
eligible for IVT. After IVT, the patient made a full recovery with complete resolution of INO.
Follow-up MRI at 1 month demonstrates the absence of ischemic lesions.

Conclusion:

Our case provides neuroradiological evidence of IVT efficacy in brainstem stroke, and it
should prompt clinicians to rapidly perform MRI in wake-up onset INO and to just as quickly administer
IVT, since INO is a functionally disabling deficit. Finally, this case demonstrates the value of MRI
in diagnostic, prognostic, and therapeutic workup of posterior circulation wake-up stroke.
Five Years of Gene Networks Modeling in Single-cell RNA-sequencing
Studies: Current Approaches and Outstanding Challenges
Authors: Das Samarendra , Pradhan Upendra , Rai Shesh N.
Published: August 2022

Single-cell RNA-sequencing (scRNA-seq) is a rapidly growing field in transcriptomics,
which generates a tremendous amount of gene expression data at the single-cell level. Improved statistical
approaches and tools are required to extract informative knowledge from such data. Gene network
modeling and analysis is one such approach for downstream analysis of scRNA-seq data. Therefore,
newer and innovative methods have been introduced in the literature. These approaches greatly vary in
their utility, basic statistical concepts, models fitted to the data, etc. Therefore, we present a comprehensive
overview of the available approaches for gene network modeling and analysis in single-cell studies,
along with their limitations. We also classify the approaches based on different statistical principles and
present a class-wise review. We discuss the limitations that are specific to each class of approaches and
how they are addressed by subsequent classes of methods. We identify several biological and methodological
challenges that must be addressed to enable the development of novel and innovative single-cell
gene network inference approaches and tools. These new approaches will be able to analyze the singlecell
data efficiently and accurately to better understand the biological systems, increasing the specificity,
sensitivity, utility, and relevance of single-cell studies. Furthermore, this review will serve as a catalog
and provide guidelines to genome researchers and experimental biologists for objectively choosing
the better gene network modeling approach.
The Role of Land Use Planning in Urban Transport to Mitigate Climate Change: A Literature Review
Authors:   University of Queensland, School of Earth and Environmental Sciences, 1, St Lucia QLD 4067, Brisbane, Australia, Deweerdt Tom , Fabre Anais ,   Griffith University 2, 170 Kessels Rd, Nathan QLD 4111, Brisbane, Australia
Published: August 2022

With the growing urbanisation phenomenon, ambitious policy interventions are needed to limit transport-related greenhouse gas emissions in urban areas. Cities are a predominant source of pollution, with urban transport contributing significantly to emissions. To address climate change, decision-makers must implement appropriate and effective mitigation instruments. This literature review focuses on the different approaches and supporting measures of urban transport land-use planning, such as mixed-used zoning plans and the compact city approach. These solutions can increase the modal shift towards zero emissions transport options. They can also reduce reliance on private vehicles and bring co-benefits and positive externalities to urban residents. Many barriers exist for policymakers, such as financial limitations or institutional immobility. Nevertheless, innovative approaches such as Artificial Intelligence and Mobility-as-a-service provide new perspectives for policymakers and can be helpful in the fight against climate change.
Hepatic Metastasis Revealing a Melanoma of the Penis: Case Report
Authors: Boui Meriem , Hammoune Nabil , Slioui Badr , Zouaki Zakaria , Atmane Mehdi , Mouhsine Abdelilah , Haouane Mohamed Amine , Azami Mohamed Amine , Kaakoua Mohamed , Assadi Ismail , Boui Mohammed , Bouhamidi Ahmed
Published: August 2022

Melanoma of the penis is a rare tumor with a poor prognosis. We report the case of a 73-year-old patient with no significant medical history, admitted for deterioration of the general condition and bilateral inguinal lymph nodes. An abdominal ultrasound and thoraco-abdomino-pelvic CT (computed tomography) scan revealed metastatic liver nodules, the tumoral nature of which was confirmed by an anatomopathological examination. Further clinical examination revealed papular and ulcerated lesions of the penis located at the urethral meatus and glans penis. These lesions were biopsied and histologically assessed as melanoma. The contribution of imaging in penile tumors is generally not useful for diagnosis as clinical examination is key. However, it has its place in the assessment of locoregional and distant extension. In our case, it was the distant lesions that helped orient the diagnosis. The patient underwent immunotherapical treatment and is still alive 19 months after the diagnosis.
Achieving Judgment by Means of Forensic Science During the Criminal Proceedings in Romania
Authors: Magherescu Delia
Published: August 2022

Achieving the function of judgment by means of forensic science during the criminal proceedings in Romania has presented a real challenge for the judicial system during the years. This challenge must be integrated within the general framework of justice in criminal matters, based primarily on the traditional principles as well as the European ones, such as due process and solving penal cases in reasonable time. The current paper aims to analyze the function of judgment and its achievement through scientific techniques and methods provided by the forensic sciences. Another aim is to consider the penal procedure imperative which leads to ensuring a fair trial. The current paper is part of a research project conducted on the three functions of penal proceedings
-
accusation, defense and judgment
-
and their achievement by means of forensic science. The research results state that regarding the function of judgment, its achievement still creates difficulties for judges in their judicial activity of interpreting scientific evidence gathered and examined by the forensic experts. This aspect indicates that there is a lack of understanding the forensic evidence among judges. Despite this deficiency that exists in the judicial activity of solving penal cases and pronouncing decision based on the forensic evidence, it is useful for judges to take into account the forensic science investigation in an inter-professional approach provided by the forensic science. In this context, the forensic experts work in close cooperation with other practitioners, such as legal forensic scientists.
Las condiciones normativas del juicio de hecho y el denominado principio de razón suficiente, a propósito del recurso de nulidad en el proceso penal chileno
Authors: Del Río Ferretti Carlos
Published: August 2022

En este trabajo se formula un análisis procesal del denominado principio de razón suficiente utilizado en el proceso penal chileno. Para ello se parte por fijar conceptos previos sobre las condiciones normativas del juicio de hecho en relación al mérito probatorio del proceso, con el fin de examinar en ese marco y contexto el sentido y el provecho que se ha querido atribuir al principio de razón suficiente, y las consecuencias que de ahí derivan para la recta aplicación del recurso de nulidad. Al respecto se ofrece un razonamiento dogmático que pretende demostrar que el principio en cuestión es un concepto innecesario y erróneo en el régimen jurídico chileno.
standard de prova para condenação por crimes sexuais
Authors: Szesz André
Published: August 2022

Os crimes sexuais fazem parte do grupo dos delitos difíceis de provar e as estatísticas de impunidades relacionadas a eles são altas. Nesse contexto, a jurisprudência nacional tem seguido o caminho da flexibilização do
standard probatório
, considerando a palavra da vítima suficiente para condenação. O presente estudo analisa o seguinte problema: é constitucionalmente viável e é eficaz, pela perspectiva de política criminal, um rebaixamento de
standard
com o objetivo de reduzir a impunidade? Argumentou-se que a atenção especial conferida à palavra da vítima deve significar a compreensão do contexto de dificuldade de obtenção de provas, o esforço para se verificar a
coerência externa
a partir dos elementos fáticos que efetivamente podem ser obtidos em cada caso e uma avaliação desprovida de estereótipos de gênero. Mas uma condenação deve pressupor confirmação sólida da hipótese acusatória por elementos independentes. A adoção de uma presunção de veracidade não é compatível com a presunção de inocência e implica uma politicamente problemática conformação com condenações equivocadas, além de sequer impactar positivamente nas estatísticas de incidência do crime. Há espaço para se melhorar a qualidade da prestação jurisdicional, mas o foco das políticas públicas deve estar sobretudo na prevenção e no combate aos fatores sociais e estruturais que estão na raiz do problema.
Processo Penal e Inteligência Artificial
Authors: Santos Hugo Luz dos
Published: August 2022

A inteligência artificial e a internet das coisas (internet of things), herdeiras legitimárias da quarta revolução industrial, mudarão para sempre o processo penal talqualmente o conhecemos. Este artigo doutrinal pretende, concretamente, dar conta do equilíbrio – muito difícil – entre a inteligência artificial e os direitos fundamentais do arguido em processo penal. Principalmente o direito à privacidade mental do arguido, que deriva do nemo tenetur se ipsum accusare. É da sinalização dessas mudanças abruptas no desenho funcional do processo penal que este artigo doutrinal curará.
Scientific criticism of “Unlawful prosecution regarding forest ecosystem destruction
Authors: Garrido Rodrigo Grazinoli
Published: August 2022

This scientific criticism was based on what was proposed in the article “Unlawful prosecution regarding forest ecosystem destruction,” aiming to expand its discussion, especially from a comparison between the Polish and the Brazilian reality. For this purpose, exploratory, documentary, and bibliographic research was carried out, allowing the recognition that the similarities in the prosecution of environmental crimes bring both countries closer together than they are further apart despite clear distinctions of environmental reality and criminal procedural diversity, especially concerning evidence.
Caminar cantando: tres ejemplos en la obra literaria de Marguerite Duras
Authors: García González Norma Angélica
Published: August 2022

¿Qué ocurre con un texto que relaciona el fenómeno corporal-sonoro que supone el canto con el acto corporal que implica el desplazamiento en el espacio? ¿Cómo se combinan los efectos de ambas acciones para lograr una exacerbación de la emoción en la lectura? Éstas son algunas de las preguntas sobre las que reflexionaremos e intentaremos responder al abordar los ejemplos de tres personajes en la obra literaria de Marguerite Duras. Analizaremos primeramente a la pordiosera en Le Vice-Consul (1966) que deambula por paisajes inhóspitos trazando el camino del exilio y al hacerlo canta una canción de infancia. Enseguida veremos cómo la profesora de L’Été 80 (1980) canta una pieza popular a un niño de cinco años para decirle indirectamente que lo ama, mientras pasean por la playa durante un campamento de vacaciones. Finalmente, abordaremos el personaje del vicecónsul que aparece en la novela homónima y que silba mientras vaga por los jardines de la embajada en busca de Anne Marie Stretter. Pensamos que, al tener varios puntos de convergencia que les permiten relacionarse, el canto y el caminar se unen para caracterizar de diferentes formas a estos tres personajes que caminan cantando o cantan al caminar, potencializando los efectos que ambas acciones conllevan en la lectura.
diversificación del arte bajo un mando vertical
Authors: Barrios de la Mora Santiago
Published: August 2022

El proyecto modernizador del cuestionado presidente electo Carlos Salinas de Gortari consistió en estrechar vínculos con Estados Unidos en todas las áreas de la relación bilateral. La reactivación de los mecanismos de legitimación y la diplomacia cultural fueron estrategias centrales de su gobierno. Para ello fue clave el momento creado en Nueva York por la exposición Mexico: Splendors of Thirty Centuries (1990) y más de doscientos eventos paralelos. Éstos fueron integrados en el programa Mexico: A Work of Art, gestionado por la burocracia cultural de Salinas. A través de entrevistas y documentos mexicanos y estadounidenses, el presente trabajo permite identificar continuidades y rupturas de las prácticas políticas de estos operadores, así como arrojar luz sobre los eventos neoyorkinos de 1990. En su papel de coordinadores-mediadores, estos operadores reactivaron un tipo de centralización estatal, sortearon las demandas de liberalización de la época e hicieron de nuevo de la cultura un mecanismo diplomático y legitimador rentable.
Performance on Fly Ash Based Geopolymer Concrete with 8, 10 & 12 Molar Naoh Activator Using M40 Grade of Concrete
Authors: Chaitanya J. Sree Naga , Chandramouli Dr. K. , Kumar Dr. D. Vijaya , Kumar T. Swarna
Published: August 2022

Abstract: Ordinary Worldwide, Portland cement is a vital building component. A source of carbon dioxide emissions alongside deforestation and the use of fossil fuels is the cement making business. The atmosphere is polluted by greenhouse gases like CO2, which contribute to global warming. CO2 makes up roughly 65% of the greenhouse gases that cause global warming. Around 7% of the planet's total greenhouse gas emissions come from the cement industry. Alternative binders for the manufacturing of concrete are required to overcome the environmental impacts associated with Portland cement. In this work, a geopolymer based on fly ash from Vijayawada with a low calcium content (Class F) was utilised. A thermal power plant was used to create geopolymer concrete. Flyash activation employed an alkaline solution made of sodium silicate and sodium hydroxide solutions. The ratio of alkaline solution to fly ash was adjusted to 0.45. The sodium hydroxide solution's concentration was kept at 8M, 10M, and 12M. (Molars). As ambient curing, different curing conditions for geopolymer concrete were used. At different ages, including 7 and 28 days, the geopolymer concrete's compressive strength and split tensile strength were evaluated. According to the test results, the strength of geopolymer concrete increases along with the alkaline solution to fly ash ratio.
The role of «point of care ultrasound» in medical triage of COVID-19 patients: a systematic review
Authors: Cherkashin M. A. , Scheparev I. S. , Berezin N. S. , Berezina N. A. , Nikolaev A. A.
Published: August 2022

INTRODUCTION: In the conditions of primary triage of patients with the new coronavirus infection, various medical imaging methods, including «point of care ultrasound», have become key.OBJECTIVE: The aim of this paper is to review data published during the pandemic on the assessment of the role of various ultrasound diagnostic methods in medical triage of patients with COVID-19.MATERIALS AND METHODS: The authors performed a systematic literature search in Russian and English for the period up to March 10, 2022 using various databases and repositories (Embase, Medline/PubMed, Researchgate, medrxiv.org, RSCI/elibrary). The search was carried out on the keywords «COVID-19», «coronavirus», «коронавирус», «SARS-CoV-2», «2019nCOV», «lung ultrasound», «POCUS», «point of care ultrasound», «прикроватный ультразвук», «ультразвуковое сканирование легких», «triage», «сортировка».RESULTS: The final analysis included 42 publications on different aspects of the use of point of care ultrasound during the pandemic. Of considerable interest are the technical features of the research, classifications and triage algorithms used in different countries.CONCLUSION: The widespread introduction of «point of care ultrasound» technology in the prehospital, emergency department and intensive care units greatly facilitates clinical decision making, including in the initial assessment of the severity of the condition of patients with pneumonia caused by SARS-CoV-2.
Differencial diagnosis of primary central nervous system lymphomas based on multiparametric MRT mapping
Authors: Talybov R. S. , Trofimova T. N.
Published: August 2022

INTRODUCTION: Primary central nervous system lymphoma (PCNSL) represent a rare and aggressive form of extranodal NonHodgkin’s lymphoma, which is in most cases confined to the brain. Prompt diagnosis and starting treatment are vital. According to imaging, the tumor is characterized by low MR signal in T1, isointense in T2, pronounced and homogeneous uptake of contrast agent and restricted diffusion.OBJECTIVE: to study the effectiveness of MR-/CT perfusion techniques, underlying the multiparametric MRT mapping with the differential diagnosis of primary CNS lymphomas in comparison with poorly differentiated gliomas (grade 3–4 WHO 2021) and solitary metastatic brain injury.МATERIALS AND METODS: The study includes 80 patients with newly identified CNS tumors, later having check-up/neurosurgery treatment in Federal Centre of Neurosurgery (Tyumen, Russia) with histological verification within the period from 2018 to 2021. Depending on histological conclusion, 4 groups of patients were identified: 1–33 cases with PCNSL (out of which 10 cases with not typical manifestation based on the data of perfusion parameters and 23 cases of classical PCNSL), 2 — with anaplastic astrocytomas — 14 cases, 3–23 cases with glioblastomas and 4–10 cases with solitary metastatic lesion. The research was held on magnetic resonance tomography General Electric Discovery W750 3Т, multispiral x-ray computer tomography Canon Aquilion One before and after the contrast enhancement.RESULTS: During the study it was established that MR-/CT perfusion is a limited imaging method, possessing ambiguous sensitivity and specificity with PCNSL diagnosis, as they are characterized by not typical manifestation considered as exception. Nevertheless, the method has some undeniable advantages being indispensable in the algorithm of complex multiparametric diagnostic approach for this type of neoplasm.CONCLUSION: The capacity of neuroimaging PCNSL, even applying improved techniques of MR-/CT data collection, is rather limited and it doesn’t always allow to differentiate this tumor with other neoplasms accurately.
The effect of corpus callosum abnormalities on myelin development in the fetal brain using the fast macromolecular proton fraction mapping
Authors: Korostyshevskaya A. M. , Gornostaeva A. M. , Isaeva Ya. O. , Petrovskiy E. D. , Yarnykh V. L.
Published: August 2022

INTRODUCTION: There is evidence, indicate early compensatory axonal remodeling connections in the prenatal period, providing a favorable neurological outcome in isolated anomalies of the corpus callosum (CC). Mapping of the macromolecular proton fraction (MPF) is proven method of quantitative determination of myelin, which has been adapted for prenatal studies.OBJECTIVE: To investigate the relationship between CC anomalies and prenatal myelination of the brain using the fast macromolecular proton fraction (MPF) mapping.MATERIALS AND METHODS: Fetal MR imaging were performed on a 1.5 scanner (Achieva, Philips) using a 16-channel body coil. Of 66 fetal brains MRI, 12 studies were selected with MT abnormalities (22.8±2.8, 19–28.5 WG) and 21 without brain pathology (23.1±2.3, 20–29.5 WG). The images were analyzed according to structural MRI data (T2-Ssh and T1-GE, EPI, DWI, MYUR, T2-BFE-DYN) by two experienced radiologists. Fast-3D-MPF scan protocol with the MPF maps reconstruction was carried out according to a specialized protocol (open-source software: https://www.macroatomicmri.org /). Quantitative data were obtained by choosing the region of interest (ROI) in numerous brain structures bilateral (bridge, medulla oblongata, thalamus, cerebellum, and cerebral hemispheres). Statistics: distinctions between the groups and structures were assessed using repeated-measures analysis of covariance (ANCOVA), Pearson correlation analysis.RESULTS: MPF was significantly increased in the CC anomalies group as compared to controls in the medulla (3.26±0.63% vs. 2.75±0.59%, р=0.001) and cerebellum (2.02±0.55% vs. 1.76±0.34%, р=0.006). In hemispheres significant correlation with GA was observed in CC anomalies group (r=0.81, р=0.002), but was absent in controls (r=0.32, р=0.16).CONCLUSION: Primary observed MPF increase in the medulla and cerebellum as well as the dependence of the large hemispheres myelination on gestational age indicates that fetal cerebral matter undergoes early compensatory axonal remodeling in the cases of the interhemispheric connections’ reduction.
High 11C-methionine uptake in brain abscess: radiological, metabolic and morphological findings: a case report
Authors: Skvortsova T. Yu. , Savintseva Zh. I. , Gurchin A. F. , Martynov B. V.
Published: August 2022

An increased amino acid metabolism is characteristic for many brain malignancies. Combined positron emission and computed tomography (PET/CT) with radiolabeled amino acids is often used in recognizing the tumor nature of the structural brain lesion detected on MRI. On 11C-methionine PET/CT a hallmark of a brain tumor is an increased amino acid uptake, topographically coinciding with a structural lesion on MRI. However, high 11C-methionine uptake in the brain lesion is not tumor specific and could be seen in a number of non-tumor diseases. The paper presents three observations of a brain abscess, radiological and metabolic data of which in MRI and 11C-methionine PET/CT simulated a malignant cerebral tumor. The reasons for patients seeking nuclear medicine examination were seizures or focal neurological symptoms, as well as a suspicion of a cerebral tumor based on the contrast-enhanced MRI. Knowledge of the non-tumor disease characterized by high 11C-methionine uptake will help avoid misdiagnosis of a cerebral tumor.
Bladder Xanthoma
Authors: Ameen Torath , Ahn Jong Seok , Carton James , Hwang Woochan , Attar Hama
Published: August 2022

A 35-year-old male presented with multiple interrupted episodes of frank hematuria and persistent micro-scopic hematuria. CT urogram demonstrated a nonspecific lesion in the bladder. Cystoscopy showed a lesion in the bladder wall that was biopsied, and histopathology confirmed a xanthoma, a rare diagnosis in the bladder. This case report performs a review of current literature and examines necessary investigations,differential diagnoses, and management required for bladder xanthoma.
Energy Management Systems in Latin American Industry: Case Study Colombia
Authors: Beltrán Gallego José David , Quintero Ríos Mauricio , López García Dahiana , Carvajal Quintero Sandra Ximena
Published: August 2022

The increase in energy demand, mainly due to the dependence of industry and transport on fossil fuels, has led to the extensive use of these fuels and an increase in greenhouse gas emissions, generating a severe environmental concern in all countries. Then, the need for a proportionate consumption of energy resources and the decarbonization of the economy to leverage the reduction of emissions into the atmosphere becomes evident. Therefore, implementing Energy Management Systems (EnMS) within industries makes sense, seeking to promote energy's rational and efficient use. Consequently, this paper presents a bibliographic review on the integration of EnMS in the industry, highlighting the main barriers and motivators for its implementation, emphasizing the leading role that management has within companies in converting these programs into sustainable initiatives in an extended time horizon. In addition, an analysis of the Latin American panorama is presented, especially the Colombian one, on the integration of mechanisms to improve energy efficiency in industries. One of the main conclusions evidenced was the need to increase support at the regulatory level for energy efficiency programs in the industry. Currently, greater prominence is given to renewable energy sources, which are a fundamental step for the energy transition but must be complemented with the rational and efficient use of resources. Here, the industry has an essential role in representing the segment of users that more energy traditionally consumes.
Cicatrizes são documentos em alto-relevo: narrativas de travestis em torno do encarceramento prisional e dos direitos humanos
Authors: Da Silva Passos Amilton Gustavo , Seffner Fernando
Published: August 2022

O presente artigo tem como foco o que denominamos como narrativa de vida visceral, que fala de sofrimentos que implicam em marcas corporais e abusos cometidos particularmente em corpos de travestis, e uma narrativa que se faz citando as experiências de sofrimento de outras travestis, fragmentos de uma história compartilhada, mesmo que vivida em tempos diferentes. Tomamos o corpo e suas cicatrizes como um documento histórico que insere, em especial, as travestis em uma cronologia de longa duração e em um coletivo que se reconhece pela situação de sofrimento que padece. As vidas sobre as quais nos debruçamos só tiveram a oportunidade de ter sua história narrada porque os olhos do poder as capturaram. A estratégia de citar, reiterada e coletivamente, a existência recorrente desses sofrimentos e da memória das que pereceram durante o encarceramento produziu uma materialidade enunciativa, sobre a qual nos debruçamos. Portanto, entrevistamos um grupo de pessoas gays, bissexuais, travestis e mulheres transexuais presas entre os anos de 2013 e 2018 em Porto Alegre, no estado do Rio Grande do Sul, e analisamos elementos de suas narrativas à luz, sobretudo, da noção de precariedade butleriana. Percebemos que a instituição prisional gerenciou vidas não percebidas como viáveis, às vezes sequer percebidas como vidas, estando na categoria de vidas precárias que necessitam de cuidados. O processo político que analisamos dialoga com o campo dos direitos humanos.
Redes y caminos de un investigador en los dos márgenes del Atlántico: Entrevista al Profesor Zacarias Moutoukias
Authors: Valdez Luísa Caiaffo , Aquino Israel da Silva
Published: August 2022

Entrevista al profesor e historiador argentino Zacarias Moutoukias, realizada en noviembre de 2018 en Porto Alegre (Rio Grande do Sul, Brasil), durante su asistencia en el II Seminário Internacional Conexões Atlânticas (II SICA), evento organizado por el Programa de Pós-graduação em História da Universidade Federal do Rio Grande do Sul (Brasil). El entrevistado es doctor en Historia por la École des Hautes Etudes en Sciences Sociales de París (EHESS) y actualmente es profesor de Historia Moderna y Contemporánea de América Latina en la Université de Paris Diderot/Université de Paris. El profesor Moutoukias investiga temas de historia política e económica de la región del Río de la Plata e de la América española en los siglos XVII e XVIII. En esta entrevista habla sobre su formación y trayectoria como historiador y sobre algunas de sus investigaciones, bien como discute algunos temas de la historiografía actual y cuenta sobre su último libro.
Espacio y clasificación poblacional frente a la pandemia de covid-19 en Cali
Authors: Ibarra Melo Maria Eugenia , Sánchez Salcedo Jose Fernando , Montes Martínez Mateo
Published: August 2022

El propósito del artículo es estudiar la estrategia desplegada por el Estado para definir territorios, clasificar personas y producir dispositivos de control en Cali durante la pandemia del covid-19 en el 2020. Los recursos simbólicos que el Estado utilizó, como parte de su estrategia de control, con base en juicios morales y en una retórica del miedo, suscitó el etiquetaje de poblaciones como desobedientes e indisciplinadas asociado con una comprensión espacial del riesgo en zonas excluidas de la ciudad, para explicar el contagio y la muerte por covid-19. En el texto se presenta un análisis que relaciona pobreza, delincuencia, espacio y transmisión del coronavirus, la cual marginaliza a sectores ya excluidos en una ciudad fragmentada como Cali. Se usan datos agregados de organismos estatales y noticias de El País y El Tiempo para identificar las definiciones e intervenciones estatales sobre los espacios de control y las poblaciones, y además se elaboran tablas y mapas para representar la delimitación de la realidad del Estado. Se concluye que la producción simbólica orientada a contener el contagio y la mortalidad, así como las intervenciones restrictivas, se legitiman con estadísticas difundidas por los medios.
An Integrated, Phase-Controlled Power Divider for Metasurface Array Antennas
Authors: Banerjee Deepayan , Diebold Aaron , Smith David R. , Boyarsky Michael
Published: August 2022

We present the design of a phased, modulated, power distribution network
for metasurface array antennas. The specific metasurface array design
comprises a series of waveguides, each feeding a sub-array of
dynamically tunable metamaterial elements that radiate at microwave
(X-band) frequencies. To remain a one-port device, the composite array
requires a power divider that can excite each branch waveguide with
equal power. Further, the power divider must also apply a prescribed
phase shift to each branch waveguide to mitigate metasurface-specific
grating lobes. The presented design features hollow metal waveguides,
with a conducting sheet patterned with metamaterial irises serving as
the upper wall. A single hollow metal main waveguide feed is used to
couple power to each of the branch waveguide. Carefully oriented slots
control both the magnitude and phase of the field distributed from the
main feed to each branch. All waveguides can be machined from a single
block of metal, with a metamaterial-patterned printed circuit board
laminated to the top of the assembly. The resulting design is
mechanically robust and capable of high power operation, while retaining
the low-cost, low power consumption, lightweight and low-profile
features common in metasurface antenna designs.
Suitability of the Left Internal Jugular Vein for CRT-D placement in the setting of Extensive Venous Occlusion: Case Report and Review of the Literature
Authors: Manongi Ngoda , Goldbarg Seth
Published: August 2022

Placement of coronary sinus (CS) leads is predominantly accomplished via
the left cephalic-axillary-subclavian (CAS) venous system. However, vein
stenosis or occlusion from long-term chronic hemodialysis in patients
with end-stage renal failure can pose a challenge. Cannulation of the CS
via the left Internal jugular vein is technically difficult but often
feasible. We report a case in which a patient with ESRD had extensive
left venous system occlusion from prior in dwelling hemodialysis
catheters, and an AV fistula contralaterally, who underwent
biventricular- implantable cardioverter defibrillator (BiV-ICD)
placement with lead insertion through the left internal jugular vein
(IJV).
Enhanced photodynamic therapy by enhancing the light energy capture efficiency of porphyrin photosensitizers
Authors: Tian Zejie , Yang Lingyan , Liu Zhenhua , Li Hui , Zhang Chaoyang , He Jun , Xiong Ziwen , Liu Yunmei
Published: August 2022

Photodynamic therapy (PDT) has received increasing attention in cancer
treatment because of its advantages such as minimally invasive and
selective destruction. With the development of PDT, impressive progress
has been made in the research of preparing photosensitizers, especially
porphyrin photosensitizers. However, the limited tissue penetration and
light energy capture efficiency of porphyrin photosensitizers have been
the two major obstacles for conventional photosensitizers. Therefore, it
is necessary to enhance the tissue penetration and improve the light
energy capture efficiency of porphyrin photosensitizers through
structural modifications. In addition, indirect excitation of porphyrin
photosensitizers using fluorescent donors (fluorescence resonance energy
transfer) has been successfully used to address these issues. In this
manuscript, we focus on how to enhance the photoenergy capture
efficiency of porphyrin photosensitizers, aiming to improve the
efficiency of singlet oxygen (1O2) production in tumor tissues and
enhance the photodynamic therapy effect of photosensitizers.
ارشادات المحميات الجيولوجية في المناطق المحمية والمحفوظة
Authors: Crofts Roger , Gordon John E. , Brilha José , Gray Murray , Gunn John , Larwood Jonathan , Santucci Vincent L. , Tormey Daniel , Worboys Graeme L.
Published: August 2022

These Guidelines are intended to help improve the conservation and management of geoheritage and geodiversity in protected and conserved areas and recognition of the interrelationships and interactions with biological features and processes. They are not a textbook on geoconservation management practice, but rather set out the essential background, context and principles. The use of best practice examples from around the world will hopefully give users renewed confidence in looking after geoheritage and in connecting geoconservation with biodiversity conservation.