bluuebunny/crossref_metadata_2025 huggingface dataset:
Inés Sánchez de Madariaga: «Matilde Ucelay. Espainiako lehen emakume arkitektoa. La primera arquitecta española. The First Spanish Woman Architect». Euskadiko Arkitektura Instituta. Instituto de Arquitectura de Euskadi, 2021, 227 págs.
Authors: Giral Ángela
Published: July 2022

Texto correspondiente a la reseña del libro "Matilde Ucelay. Espainiako lehen emakume arkitektoa. La primera arquitecta española. The First Spanish Woman Architect", publicado en 2021 por el Instituto de Arquitectura de Euskadi (Euskadiko Arkitektura Instituta). El artículo analiza esta edición trilingüe en español, euskera e inglés, que recoge tanto la biografía personal como la profesional de la primera mujer titulada en arquitectura en España.
Psychological and pedagogical support for the quality of life of persons with disabilities
Authors: Viktoria Shevchuk , Olena Vlasova , Vitalii Zaika , Volodymyr Morgun , Yuliia Kaliuzhna
Published: July 2022

The current sociopolitical, socioeconomic, and sociocultural situation in Ukraine is complicated because of the continuing aggression of the Russian Federation and because of significant structural changes associated with global transformation processes of a long-term nature. Under these conditions, the society is looking for ways out of the situation to overcome the consequences of destruction, the decline in living standards, the disintegration of the system of values, social inequality that emerged, and deterioration of the quality of social institutions that implement its full-fledged activities. At the same time, the situation of socially disadvantaged groups of the population, among which the person with disabilities (hereinafter - the disabled) occupies a leading place, as the former mechanisms of solving problems do not work, and the new ones have not yet been formed, is worsening. Such people constantly have feelings of unsettlement, helplessness, and impasse, which cause the emergence of aggressive reactions, and sometimes complete indifference. As a result, social tension develops in relationships in society, which becomes a source of threat to social security, especially during the COVID-19 pandemic and military operations, which leads to overloaded health care systems with an increased number of hospitalizations and deaths.
Study the effect of piroxicam treatment for intrauterine insemination using density gradient for sperm preparation
Authors: Naser Intesar F , Al-Dujaily Saad S. , Al-Anbari Lubna A.
Published: July 2022

Back ground: Endometrium contraction following  intra-uterine insemination(IUI) was considered one of implantation failure causes.Aim of the study: The primary purpose of the study was to ascertain the effect of piroxicam treatment on pregnancy outcome following six days of intrauterine insemination. Materials and Methods: The study was accomplished in the High Institute for Infertility Diagnosis and Assisted Reproductive Technologies, Al-Nahrain University through the period from Nov. 2020 till Oct. 2021 .Forty infertile couples were selected randomly for IUI and divided into 20 couple treated with piroxicam and other 20 couples were not treated with piroxicam. The semen samples were prepared by discontinuous density gradient. Results: There was no significant differences regarding mean FSH level (p=0.769), LH level(p=0.79) prolactin level (p=0.299), E2 level (p=0.348) and TSH level (p=0.950)between the studied groups. There was no significant difference in dominant follicles counts, follicular sizes or endothelial thickness between the two groups. The results showed  a significant improvement in sperm motility and morphology (p < 0.05) after in vitro activation by density gradient technique  compared to before activation. In the piroxicam group ,4 out of 20 women became pregnant while in non-piroxicam group ,3 spouses were pregnant 15%when density gradient activation technique was used.
Study the pathogenicity of Providencia Vermicola in mice
Authors: Ameer Ahmed Kazem Al , Al-Gburi Nagham Mohammed
Published: July 2022

P. vermicola is an opportunistic pathogen of human and animals. To estimate the pathogeneses of P.vermicola in mice infected orally and I/P with 1x108 CFU/ml).The histopathological changes at 24 hrs showed infiltration of inflammatory cells and apoptosis in hepatocytes in the liver, infiltration of inflammatory cells around a congested blood vessel and interstitial tissue of kidney; lung revealed congestion of blood vessels, infiltration of inflammatory cells and alveolar emphysema; intestine appeared infiltration of mononuclear cells in mucosa layer with hyperplasia of goblet cells. In mice infected I/P, the liver showed infiltration of inflammatory cells in a necrotic area with granulomatous lesion formation, the spleen showed depletion of white pulp. The kidney revealed dilatation of bowman’s space with vacuolation of glomeruli. The intestine appeared infiltration of inflammatory cells in mucosa and submucosa layers with hyperplasia of goblet cells, also, the lung showed infiltration of inflammatory cells in interalveolar septa and alveolar emphysema.
Phenotypic and genotypic study of some virulence factors for main bacteria which caused to UPEC
Authors: Rahim Rabab Ibrahim , Abdulla Nibras Yahya
Published: July 2022

The study was aim to isolating and identification of bacteria from urinary tract infection. The present study includes 240 samples collected from patients suffering from urinary tract infection during the period extended from September 2021 to December 2021 (female and male ). From 240 specimens 160 (66.6%) samples were females and 80 (33.3 %) were males .Out of the total 240 specimens only 195 (81.3%) specimens showed significant bacterial growth ,135(69.2%) of female specimens and 60 (30.7%) from male specimens. The result of our study found that the many bacterial species are responsible for causes urinary tract infection , they have been included 9 bacterial species and the most common pathogen was Escherichia coli 85 (43.5%) , Klepsiella pneumonia 32 (16.4%) ,Enterobacter19(9.7%), S. aureus 20(10.2%) , S. sarophyticus 10 (5.1%) Proteus mirabilis 9 (4.6%), Pseudomonas aeruginosa 9 (4.6%), Citrobacter koseri 9(4.6%) and Salmonella typhi 2 (1%). In this study, some of virulence factor were detected by phenotypic methods while others detected by phenotypic and then genotypically by using PCR techniques. The phenotepic investigated include biofilm formation, capsule produced, hemolysis and enzymes which were protease, DNase, and gelatinase.
Molecular study of some pathogenic bacteria associated with the diabetes patients
Authors: Hussien Fatma Hassan , AL-Ammar Mahdi Hussein
Published: July 2022

The study aimed to isolation and identification of aerobic bacteria from diabetic foot ulcers in diabetic patients and investigation the resistance of bacteria to antibiotic agents phenotypically and genotypically. The present study included 50 specimens collected from patients suffering from diabetic foot ulcer for both sexes with an age ranged between (20 -60) years. The results showed that 11 (22%) % isolates were belonged to P. aeroginosa, 8 (16%) isolates were K. pneumonia, followed by Acintobacter baumanii with 8(16%) isolates, Proteus mirabilis 6(12%), E.coli 5(10%), S. aereus 11(22%), and S. epidermidis 4(10%).  The dominance bacterial isolates,   were P. aeruginosa 11(22%), K.pneumonia 8(16%), and A. baumanii 8(16%) that isolated and diagnosed from clinical specimens of diabetic foot ulcer and detect the antibacterial resistance phenotypically and genotypically.
Quality by design (QBD) approach to develop stability indicating RP-HPLC method development for naproxen and pantoprazole
Authors: Ahmad Sufiyan , Ashwin Bagul , Rahman Bakhshi Abdul , Gorad Rajshri Uttam , Tare Harshal
Published: July 2022

Background and Objectives: As per requisition of current regulatory requirements, simple, rapid and sensitive method by 33 factorial QbD approach was established and validated for Naproxen (NPX) and Pantoprazole (PPR) by RP-HPLC. Method: A simple RP-HPLC method has been developed and validated with different parameters such as linearity, precision, repeatability, LOD, LOQ, accuracy as per International Conference for Harmonisation guidelines (Q2R1). Statistical data analysis was done for data obtained from different aliquots Runs on Agilent Tech. Gradient System with Auto injector, UV (DAD) & Gradient Detector. Results: Equipped with Reverse Phase (Agilent) C18 column (4.6mm x 100mm; 2.5µm), a 20µl injection loop and UV730D Absorbance detector at 239 nm wave length and running chemstation 10.1 software and drugs along with degradants were separated via Methanol: (0.1% OPA) Water (75:25) of pH 3 as mobile phase setting flow rate 0.7 ml/min at ambient temperature. The developed method was found linear over the concentration range of 10-50 μg/ml for NPX and 4-20 μg/ml for PPR while detection and quantitation limit were found to be 0.2375 (ug/mL) and 0.7199 (ug/mL) for NPX and 0.1028 (ug/mL) and 0.3059 (ug/mL) PPR. Conclusion: There are no interfering peaks underperformed degradation conditions.
Comparative study of copper, zinc levels in uncontrolled type 2 diabetes mellitus with normal subjects
Authors: Karthik G , Nataraj Nataraj , Shantha Kumari N , Srinivasa K V
Published: July 2022

accounts for majority of the cases, can lead to multiorgan complications. Direct association of minerals  , Trace elements and vitamins in the pathogenesis and natural cause of  type 2 diabetes mellitus has been observed in many research studies. Aim: To estimate the levels of Copper , Zinc and HBA1c in uncontrolled Type 2 Diabetes mellitus patient. Material and methods: A cross sectional analytical studies was conducted in DR B R AMC. Study group included 40 known case of uncontrolled Diabetes mellitus. Results: In the present Study serum copper levels in uncontrolled Type 2 Diabetes Mellitus patients was 204.3 ± 49.0 and in controls it was132.4 ± 20.2. There was a statistically significant increase in the mean copper values in uncontrolled Type 2 Diabetes Mellitus patients  (P< 0.0001). Serum Zinc levels in uncontrolled Type 2 Diabetes Mellitus patients was 174.7 ± 31.0  µg/dl and in the controls it was 207.4 ± 36.6 µg/dl. There was a statistically significant decrease in the mean Zinc values  (P<0.0001).  Conclusion: Trace elements play a vital role in maintaining the normal metabolism and homeostasis.
study the gallbladder carcinoma with finding under MR imaging
Authors: Asmita Asmita , Kumar Sunil
Published: July 2022

Aim: To study the Gallbladder carcinoma with finding under MR imaging. Methods: This prospective study was undertaken at Department of Radiodiagnosis Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow association with departments of Gastromedicine and Surgical Gastroenterology. This study was approved by the institution ethics committee, SGPGI. Study included 30 patients in our study who diagnosed as gall bladder carcinoma. The consent process included an initial examination for MRI compatibility and discussion of major safety criteria. Patients in the age range of 20-75 years with a diagnosis of gall bladder carcinoma and presenting with obstructive jaundice or abdominal mass, who were referred for MRI, were selected for the study. Results: Total 30 patients were included in our study. Pathological confirmation was done in all patients, 28 patients under gone cytopathology from GB mass and in two patients from surgical specimens. Among our 30 patients, the peak incidence age group was between 41 to 60 years. The age of patients ranged from 30 to 70 with a mean age of 51 years for female and 49 years for males with a gender distribution of 11 males (36%) and 19 females (63%).
Management of distal benign biliary stricture
Authors: Ghobara Amr Sameh , Abo-Ryia Mohammad Hamdy , Saber Sherif Abdel-Fatah , Moussa Gamal Ibrahim , El-Khadrawy Osama Helmy
Published: July 2022

Endoscopic treatment consists of passing the stricture and placement of at least one large bore plastic stent, followed by further sessions of stenting with multiple plastic stents. Temporary placement of multiple plastic stents is the recommended approach in patients with benign biliary strictures. Self-expandable metal stents have a larger diameter compared to plastic stents and can be covered and uncovered. Placement of uncovered metal stents in patients with benign biliary strictures is strongly discouraged. However, covered self-expandable metal stents can be safely placed in selected patients.
efficient training strategy for classification using deep neural network with hybridization of quantum enthused artificial bee colony algorithm
Authors: Anusuya R , Sakkarapani Krishnaveni
Published: July 2022

Deep Neural Network (DNN) is commonly used in many applications of Artificial Intelligence (AI) like robotics, speech recognition and computer vision. DNN is mainly used as it produces higher classification accuracy and its cost of computational complexity is also less when compared with other classifiers.  The DNN training (DNNT) is a process by which weight set has to be optimized in order to get higher classification accuracy. Normally this training is done using Back propagation algorithm (BP) which has several drawbacks like very slow in finding local minima and computational complexity. Hence to overcome these drawbacks an evolutionary algorithm like swarm intelligence has been modified and applied in this proposed method. Normal PSO, ABC algorithm has also many drawbacks which have to be rectified using some hybrid techniques. Hence a new hybrid technique of quantum enthused artificial bee colony (QEABC) has been proposed for training DNN. The parameter setting used for this algorithm has helped a lot to get higher performance.  In our proposed hybrid technique the parameter setting is performed automatically to enhance results of classification accuracy and other metrics.
Phytochemical and pharmacological investigation of some medicinal plants for the treatment of hepatoprotective & antioxidant activity
Authors: Maurya Arun Kumar , Sidqqui Nadeem Ahmed
Published: July 2022

The plant Luffa acutangula var. Amara is used by native practitioners. Presently, it is planned to make petroleum ether, alcohol, and aqueous extracts of this plant's fruits before undertaking blind screening trials to examine the antidiabetic, hepatoprotective, and antibacterial effects of the fruits and validate native practitioners' claims. The powdered whole fruits were extracted with petroleum ether, alcohol and chloroform water. The LD50 values for all these extracts were found to be 70 mg/kg, 500 mg/kg, and 15g/kg respectively. Alloxan-induced diabetes in 150-200g albino rats was tested for antidiabetic effects and compared to glibenclamide. Albino rats treated with CCl4, a liver toxicant, had increased SGOT, SGPT, SALP, direct and total bilirubin, serum cholesterol, and serum triglyceride levels. Compared to CCl4-treated group, findings were significant. In a CCl4 hepatotoxic model, alcoholic and aqueous extracts significantly decreased wet liver weight and volume, indicating hepatoprotective action. Histopathological abnormalities (fatty infiltration, necrosis, etc.) were normalised in aqueous and alcoholic extract groups.
effect of rusavastatin on glycemic index in hypercholesterolemic adult male rats
Authors: Al.Shammary Sarah M. , Hassan Sura S. , Almulla Aussama A.
Published: July 2022

The present experiment was investigated to study the effect of Rosuvastatin on glycemic index in rats that exposed to hypercholesterolemia. Sixteen matured male rats it was used in that study, were arbitrary chose and identically grouped up in to two coteries as follows C, T. They were dosed by oral intubation (daily) for 42 days as follows; C: control group, were supplied distillated water by dosing needle, T: animals of this group were given Rosuvastatin statin 0.3mg/kg/day/kg/day + 10 g\day cholesterol within diet  orally. The daily supplementation of statin enhance i a significant increase in glucose concentration and insulin resistance, also there was significant decrease in insulin hormone & in IGF-1 in (T) group as compared to control group respectively. Moreover, the histopathological examination showed that clear space of fatty degeneration in cardiac  muscle fiber, also cross section of liver showed vacuolar degeneration in the hepatocytes with inflammatory cells infiltration  around  blood vessels in addition to few  fatty vacuoles. In conclusion, the results from this investigation approve that rosuvastatin supplementation to rats has an bad effect on heart muscle and hepatic portal system in hypercholesterolemic infected rats.
Comparison of serum troponin level and echocardiographic parameters between male and femal patients with ACS
Authors: Merza Wafa M.
Published: July 2022

Background: Acute Coronary Syndrome is one of the commonly diagnosed life threatening condition as of now. Hence it is necessary to diagnose early and assess the severity of disease as soon as possible. Troponin is considered a specific marker for the diagnosis of acute coronary syndrome (ACS). Aim: To estimate the high-sensitivity cardiac troponin (hs-cTn) in Acute coronary syndrome patients. Also to compare serum troponin levels and echocardiographic parameter in patient's gender. Materials and Methods: 70 patients of both sexes who got admitted within 24 hours after onset of symptoms and diagnosed as Acute Coronary Syndrome in Hospital of Baghdad /medical city  during the period of December 2020 to December 2021. The (hs-cTn) was measure in the blood with Elisa Assay kit. Results: This study included 70 patients, they divided into two groups: Male group and female group. The control group included 20 healthy persons. There was a significant increase in the frequency of ACS among males in comparison to females (P-value =0.0027). The mean (± SEM) value of serum hs-troponin I concentrations did not differ significantly (p=0.372) as compared with mean (± SEM) value of serum control group.
Thiopentone sodium versus propofol for anaesthesia in modified electro-convulsive therapy (ECT)
Authors: Sharma Tejash , Chhasatia Anupsinh H , Patel Jignesh , Chauhan Dinesh
Published: July 2022

Objectives: To compare the effects of thiopentone sodium and propofol as an intravenous anaesthetic agent in modified ECT. Methods: 100 patients of ASA I & II grade were randomly assigned in to two groups. Both groups were premedicated in ususal manner. Patients in Group A were induced with inj. thiopentone sodium 3-5mg/kg and in Group B inj. Propofol 1.5-2mg/kg. Then, Inj. Succinyl choline 0.5-1mg/kg was given. Patients were ventilated with 100% oxygen with bain circuit and mask. Shock was given after putting bite block. Patients were again ventilated till spontaneous respiration after seizures. Results: Propofol is better induction agent as compared to thiopentone sodium in terms of faster induction, better haemodynaemic stability, no significant effect on seizure duration, early recovery without any side effects. Conclusion: Propofol in the dosage of 1.5-2 mg/kg body weight intravenously can be safely used for modified ECT in ASA grade I and II pateints. Fast, smooth induction, better hemodynamics, early smooth recovery, antiemetic property and uncompromised therapeutic outcome makes propofol as an agent of choice for day care procedure. Though there is reduced seizure duration with Propofol as compared to thiopentone, there is no effect on outcome of the therapy or effectiveness of ECT.
study on arterial patterns of human heart and their variations by using post-mortem coronary arteriogram in Tirupathi population
Authors: Reddy J. Vasudeva , Kumari K. Praveena , Lokanadham S.
Published: July 2022

Background: The impact of post-mortem angiography increases because of the rapid evaluation of organ-specific vascular patterns, vascular alteration under pathologic and physiologic conditions and tissue changes induced by artificial and unnatural causes. Aim: To study the human heart arterial patterns and their variation by using post-mortem arteriogram. Materials and Methods: Eighty human fresh heart specimens were obtained from the Forensic Department, S.V. Medical College, Tirupati. The hearts were perfused with normal saline followed by injection of barium sulphate suspension and ligated at the proximal end of coronary arteries. Skiagrams were taken in different views and studied. Results: we have observed all the branches of right and left coronary arteries. The right and left dominance pattern, Vieussens annulus, anastomosis between the great blood vessels and posterior interventricular branches, AV nodal, SA nodal branches and variations of branches were noted in our study Conclusion: Our study will be useful in analyzing the arterial system of the heart and gives valuable supplement to conventional autopsy procedures.
Deliberated thinking among medical group students
Authors: Yaqoubi Haider Hassan , Al-Sayed Salman Deiy Waddah
Published: July 2022

The research aims to: Identify the Deliberated thinking of the students of the medical group at the University of Kufa. As well as the statistically significant differences in the Deliberated thinking of the medical group students according to the college variables (medicine, pharmacy, dentistry, nursing), gender (students, female students) and academic grade (first, second, third, fourth, and above) and to achieve the objectives of the research The researchers built two research tools: Deliberated Thinking Scale. The research tools were applied to the basic research sample consisting of (466) male and female students from the University of Kufa, the medical group, with a percentage of 10% of the original community, using the proportional random stratified method, after data collection and statistical analysis using the package. Statistical data for the social sciences (SPSS), the researchers reached the following conclusions: The research found the results in terms of Deliberated thinking that male and female students from the medical group at the University of Kufa enjoy Deliberated thinking.
Phenotypic and genotypic study associated with biofilm formation for E. coli isolated from UPEC
Authors: Rahim Rabab Ibrahim , Abdulla Nibras Yahya
Published: July 2022

UTI is a serious health problem with respect to antibiotic resistance and biofilms formation being the prime cause for the antibiotic resistance. In current study sixty E.coli isolated collected from patients with urinary tract infection. In this study, biofilm formation were detect by phenotypic and genotypic methods. The detection of biofilm formation  by phenotypic method was carried out by Congo Red Agar (CRA) method and tissue culture plate (TCP) method and the genotypic method performed by detection present some gene associated with biofilm formation which include fliC ,csgA ,fimH and papC.. The results showed that 54(90%) from E. coli produced strong and moderate slime layer. The present study showed that 57(95%) from E. coli produced strong and moderate biofilm. Genotypic study of E. coli biofilm-associated genes were found in various frequencies in all isolates that included fliC (63.3%), csgA (73.3%), fimH (90%) and papC (76.6%).
Effect of Yoga therapy with sattvic diet on endometrial thickness among reproductive girls suffering with polycystic ovary syndrome
Authors: Nalini G. , Elangovan R.
Published: July 2022

The aim of the random group experimental study was to find the effect of yoga therapy with sattvic diet on endometrial thickness among reproductive girls suffering with Polycystic Ovary Syndrome. To achieve the purpose of the study, 45 were screened using Rotterdam Criteria and 30 were finally selected randomly by using randomized control sampling method. It was hypothesised that there would be significant differences on endometrial thickness due to yoga therapy with Sattvic Diet than the control group. The subjects (30) were divided into an experimental group (Yoga Therapy with Sattvic Diet) and control group of 15 subjects each. Experimental group was imparted training for 24 weeks, six days a week and the control group was in active rest with their regular activities. The pre-test and post-test were conducted before and after the intervention for the experimental and control group and the scores on endometrial thickness was measured. Analysis of covariance (ANCOVA) was used to find out the significant differences among the groups.
Analysis of utilization pattern of antimicrobial agents
Authors: Dhone Pravin , Jain Mahesh , Rathore Rajkumari , Sahoo Annapurna
Published: July 2022

Antimicrobial Agents are commonest used medicaments in all type of health faculty and specialty. It will not be trust worthy if one will say that he or she has not used Antibiotics in his life time or cannot claim that will not use antibiotics in future. To find out rationality of Anti-microbial use in different IPD BURN WARDS of a tertiary care.  All prescriptions single or combination of AMAs is included. No age, sex, race, residence, addictions and habituations, socio-economic state, co-morbid condition, height, weight not taken into account, except weight, age and co-morbid conditions such as liver and renal failure taken to determine type and dose of AMAs. Topical antibiotics, ointments, combination of antibiotics with steroids for local applications, ATT, HAART, Antineoplastic drugs, Antifungal antibiotics are not taken into study. The antimicrobial stewardship program is a must for every hospital and it should seek to achieve optimal clinical outcomes related to antimicrobial use, minimize toxicity and other adverse events, reduce the costs of health care for infections, and limit the selection for antimicrobial resistant strains.
cognitive structure of graduate students
Authors: Saleh Alaa Gameel
Published: July 2022

The current research aims to identify the cognitive structures of graduate students in the universities of the Middle Euphrates as well as the statistically significant differences in the cognitive structures of graduate students according to gender (male-female), specialisation (scientific-human), and study (Master-PhD), and to achieve the objectives of the research, the researchers built a research tool: the cognitive structure scale, so the tool was applied to the basic research sample (643) of male and female graduate students in the universities of the Middle Euphrates (Karbala, Babylon, Kufa, Al-Muthanna, Al-Qadisiyah) and to the scientific and humanitarian specialists. After stratifying the original population by 10% using the stratified random method, and after collecting and analysing data statistically using the SPSS statistical package for social sciences, the researchers reached the following results: The postgraduate students in the universities of the Middle Euphrates are characterised by cognitive structures. They know that the knowledge structures in their educational world, knowledge structures in their information world, and knowledge structures in their social world did not show any clear structures in their economic world, that PhD students are more than master’s students in cognitive structures.
Microleakage comparision in class V Cavities using different glass ionomer cements
Authors: Hora Baljeet Singh , Sawhny Asheeh , Vizo Virginia , Bansal Mukta , Singh Rashmi , Sarkar Debajit
Published: July 2022

Aim: The aim of this study was to compare the microleakage of Conventional  Glass Ionomer Cement(CGIC),Resin Modified Glass Ionomer Cement (RMGIC)and Nano-Filled Resin Modified Glass Ionomer Cement (RMGIC). Materials and Methods: forty five sound extracted human molar teeth were selected. Teeth were randomly divided into three groups of 15 teeth each and restored as follows: Group 1-CGIC; Group 2-RMGIC; and Group 3-Nano-filled RMGIC. Datas were analyzed using Kruskal-Wallis and Wilcoxon tests. Results: There was no statistically significant differences in dye leakage between the three restorative materials for occlusal margins (P = 0.465).At the gingival margins, Group 3 showed significantly less microleakage than Groups 1 (P = 0.008) and 2 (P = 0.041). The degree of microleakage in the gingival margins of each group was higher than that found in occlusal margins. Conclusions: No material was able to completely eradicate microleakage at enamel, dentin, or cementum margin. Nano-filled RMGIC show significantly less microleakage as compared to other two cements at gingival margins.
influence maternal role in the stimulation of puzzle therapy and identification of animal sounds on the cognitive development of stunting children at toddler age
Authors: Arini Diyah , Nursalam Nursalam , Sari Esti Yunita , Mahmudah Mahmudah , Suhardiningsih A. V. Sri , Riestiyowati Maya Ayu , Betrixiana Bella
Published: July 2022

Backgrounds: Stunting is a condition in which a child is shorter than his age. Stunting can have a negative impact on children's development, namely children's cognitive development becomes hampered. Role of motherbecome important in providing stimulation to the cognitive development of stunted children under five. The role of the mother here is to provide stimulation of cognitive development through educational games. The purpose of this study was to determine the effect of maternal role in puzzle therapy stimulation and identification of animal sounds on the cognitive development of stunted children under five. Methods: Quasy-experimental research design. The sampling technique used was simple random sampling on 28 stunting children aged 3-5 years in the Kenjeran Public Health Center Surabaya. The independent variable is puzzle therapy and identification of animal sounds and the dependent variable is the cognitive development of stunted children under five. The instruments used are DDST and standard operating procedures for puzzle therapy and animal sound identification. Data analysis was performed using the Wilcoxon and Mann Whitney test with significant (p = 0.05).
Immune response towards viral and bacterial infections due to COVID-19
Authors: Baboolal-Frank Rashri
Published: July 2022

COVID-19 has caused drastic changes to the immune response towards viral and bacterial infections. There have been clinical studies that have shown that there are long impacting imprints on immunity relating to the SARS-CoV-2 virus that has changed the immune response. It is evident that people with immune suppressed issues are more vulnerable to more viral illnesses, than before as their environmental immunity did not develop fully due to lockdown conditions imposed. In South Africa, a country that is riddled with medical conditions such as tuberculosis, diabetes, heart diseases, cholesterol, high blood pressure, obesity, cancer, HIV and AIDS endemic which illnesses and viruses exposes these groups to be more vulnerable to contracting SARS-CoV-2 variants and influenza. The paper explores immune therapy and boosting that shall enhance compromised immune systems to overcome fatal infections. The paper postulates different strategies for international collaboration that may be undertaken to overcome the pandemic fully and permanently.
Vitamin d deficiency and effect of its supplementation on interstitial lung disease (ILD): a randomized clinical trial
Authors: Ahmed Naglaa Bakry , Abd-Elnaby Esmat Ali , Abd-Elnaiem Samah Selim , Rabie Walaa Ahmed , Ibrahim Rania Othman
Published: July 2022

Background: Vitamin D is a steroid hormone that affects the immune system, lung remodeling, and bone health. Aim of the work: to assess serum vitamin D level in non-connective tissue disease-associated interstitial lung diseases (ILD), and to evaluate the impact of vitamin D supplementation. Patients and methods: One hundred and four patients with different types of ILD were randomly assigned to either; Group 1 (intervention): included 52 patients who received vitamin D for 3 months besides their standard treatment, and Group 2 (control): included 52 patients who received only the standard treatment of ILD. Follow up after 3 months. All patients were subjected to; dyspnea scoring, spirometry, six minutes walk test (6-MWT), and measurement of serum vitamin D at the time of enrollment and after 3 months for the intervention group. Results: The mean serum vitamin D level was (8.53 ± 6.29) ng/ml. After 3 months of supplementation; it significantly increased [5.7 to 18.5 (ng/ml), p < 0.001], dyspnea score significantly decreased, significant increase of forced vital capacity (FVC)% and forced expiratory volume in the first second (FEV1)% (P=0.004 & 0.02), with improvement of six minute walk distance (6-MWD) and oxygen saturation.
The clinical and histopathological assessment of nasal mass amongst patients in ear, nose, and throat.
Authors: Toppo Shankar Marshal , Gupta Vikas , Gulati Rahul , Dhone Pravin G.
Published: July 2022

The nose of the prominent feature of the face and often catches the attention of the face and often catches the attention on the looker whenever it is deformed or altered in shape. Nose is not only important functionally, but automatically and aesthetically as well as. What is pleasing and what is pleasing and what is beautiful is difficult to answer and depends upon the emotional reaction of the be holder. The observations are made from the study of 130 patients with mass in nose attending E.N.T. Department of V.S.S. Medical College Hospital, Burla from September 2009 to August 2011. Out of total number of 20,215 patients attending E.N.T. OPD 459. 130 cases of mass in nose, attending the ENT OPD, VSS Medical College Hospital, Burla from September 2009 to August 2011 were taken for study, which comprised 0.64% of total patients of that period. Rhinosporidiosis was found        to    the most  common     lesion (34.61%) among them followed by AC polyp (16.92%) & Ethmoidal polyp (13.84%). Hemangioma constitute 7.71% of cases, Sq cell papilloma 4.6°/o inverted papilloma 2.3%, nasopharyngeal angiofibroma 2.2%.
Observation of various symptoms of non-neoplastic nasal mass in ent
Authors: Meher Bhanjan , Marandi Gujaram , Beshra Sabitri , Dhone Pravin G.
Published: July 2022

Tumors in the nasal cavity and paranasal sinuses were recognized during the time of Hippocrates. Whillis (1948) defined tumors as “an abnormal mass of tissue, the growth of which exceeds and is coordinated with that of the normal tissues and persists in the same excessive manner after cessation of the stimuli which evoked the Change” From the table I it is evident that only 5 cases of malignant and 3 cases of fungal Granuloma, there was bony erosion. In 19 cases of antro chonal polyp and antrum and ethmoid sinus is found to be hazy. From the table I, on radiological study, sinuses are found to be hazy in 86.4% cases of antro choanal polyp and 89.4% cases of ethmoidal polyp. This finding is in accordance with that of miles (1971) who started that usually there is some degree of opacity of sinuses either due to thickening of mucosa or superadded infection. erosion of bone is found in 70% cases of malignancy and the 3 case of fungal granuloma.
The incidence of maxillary sinus carcinoma in nasal mass
Authors: Brahma Sujeet Kumar , Minj Anupam , Behera Desabandhu , Dhone Pravin G.
Published: July 2022

The external nose is pyramidal in shape with its root above and base directed downwards. The framework is composed of bones and cartilages. The bones are the two nasal bones articulating medially. Laterally they articulate with the frontal process of maxilla, superiorly to the medial part of nasal notch of frontal bone and inferiorly to the lateral cartilage of nose and posteriorly with the perpendicular plate of ethmoid bone. Considering the malignant conditions of nose &   PNS, the most common issq.  cell carcinoma of maxillary sinus (37.S°lc>), followed by S. q cell carcinoma of nose (25%), and then Adenocarcinoma of maxillary sinus (1 2.5%), Sq. cell carcinoma of Ethmoid sinus (12.5%) & adenoid cystic carcinoma of maxillary sinus (12.5°/o) These findings are comparable with reports of Cheesman (1957) , who had noted that Sq. cell carcinoma comprised of 80% of cases & Bahadur et al (1984), who reported that most common was Sq. cell carcinoma (65%).Followed by  adenocysticcarcinoma (12%), Adinocarcinoma (12%) Meliginate lanoma (2%) olfactory neuroblastoma(2%).
The level of incidence of rhinosporidiosis in nasal mass in ear, nose and throat.
Authors: Minj Anupam , Armo Usha , Alam Naushad , Dhone Pravin G.
Published: July 2022

According to Swindle (1935) in the mucous membrane of the nose the arrangement of the blood vessels consists of a superficial venous plexus and a deeper arteriolar. System, arranged parallel to the long axis of the nose. The relationship of taking bath in infected pond and agriculture work is explained by the above observation. There is no specific occupational incidence in other of nasal mass in the present series. Out of 8 cases (6.15%) of malignant tumours, sq. cell carcinoma is the most common (66%), in which three cases (37.5%) were sq. cell carcinoma of maxillary sinus, 2 cases of sq. cell carcinoma of nose & 1 case of sq. cell carcinoma of ethmoid sinus. Nasal masses are more common on 2nd decade (33.33%) followed by 3rd decade (26%). Malignancy of nose /PNS are found in 4-6th decade of life. Nasal masses are more common in males (71%)
Parkinson’s in Farmers, Could it be Caused by the Paraquat Herbicide Exposure?
Authors: Sukadi Arriz Akbar , Fitriani Dewi Yunia , Khoe Levina Chandra
Published: July 2022

Many studies have been carried out to assess the safety of the widespread use of pesticides in agriculture with diseases in farmers. A 52-year-old female farmer suffered Parkinson’s after working 27 years using paraquat herbicide. This study was conducted to obtain answers about the impact of paraquat exposure on the incidence of Parkinson’s in farmers through evidence-based case reports (EBCR) derived from a literature review.The review was conducted through the search and selection method of articles in PubMed, ProQuest, and Cochrane Library to answer research questions. The article search process used the keywords “paraquat AND Parkinson AND farmer”. Article selection was carried out using predetermined inclusion and exclusion criteria. In the initial search, 35 articles were retrieved and through the selection process three articles of the meta-analysis systematic review were selected.Selected articles from Tangamornsuksan and Vaccari show a statistically significant association between paraquat exposure and the incidence of Parkinson’s disease (PD) in workers, with a pooled OR of 1.70 and 1.24. Meanwhile, Yan’s study shows that duration of exposure to pesticides increases the risk of PD. The result showed a 5 and 10 years of duration exposure to pesticide were associated with a 5% and 11% augment in the risk of PD. All studies applied validation to reduce bias and heterogeneity effects or inadequate statistical methods.Based on the results of this evidence-based case report, it shows that the epidemiological studies taken can prove the possibility that Parkinson’s disease in this farmer is caused by exposure to paraquat.
Community Diagnosis of Knowledge, Attitudes, and Practices Towards COVID-19 Prevention in Koja, DKI Jakarta Province, Indonesia
Authors: Agus Sugiharto  , Damar P. Susilaradeya  , Reza Haryo Yudanto  , Rasyad Khalifah  , Anastasia Asmoro  , Dian Aris Priyanti  , Julietta Tantri
Published: July 2022

Background: The spread of COVID-19 in Indonesia was happening rapidly. The DKI Jakarta Province was the province with the highest prevalence of COVID-19. Thus, all areas in DKI Jakarta Province require special attention in the spread of COVID-19, one of which is Koja District, North Jakarta. This study was conducted to find out community diagnoses related to knowledge, attitudes, and practices regarding COVID-19 prevention.Methods: This study uses community diagnostic steps and quantitative analysis with a cross-sectional approach. The study was conducted from May 26 until June 5, 2020. The population was 115 people who seek treatment at the Koja Health Center, North Jakarta. Socio-demographic characteristics, as well as knowledge, attitudes, and practices related to COVID-19 prevention, were collected through a self-reported questionnaire. Data analysis were used by IBM SPSS version 26.0.Results: Among 115 respondents, 58.3% had good knowledge, 64.3% had a positive attitude, and 55% had positive practices related to COVID-19 prevention. The median values of knowledge, attitudes, and practices are 8, 24, and 25. The median value of knowledge is higher than the mean value, and others are almost the same as the mean value. The percentage of correct knowledge is above 90%, except for knowledge about people infected with COVID-19 who are asymptomatic (64.3%) and children who cannot be seriously ill/die if exposed to COVID-19 (33.9%). More than half of the participants had positive attitudes and practices towards the preventive measures in question, except attitudes about family members at home having to keep their distance and wearing masks inside the house (48.7%) and practices about continuing to travel outside the house (36.5%).Conclusion: Community diagnosis in Koja District, North Jakarta, more than half of the community has a sufficient level of knowledge, positive attitudes, and practices towards COVID-19 prevention. These findings still require further intervention, so that people’s knowledge, attitudes, and practices regarding COVID-19 prevention are better, especially regarding children infected with COVID-19, the importance of keeping a distance and using masks at home, and traveling outside the home. So that the provision of education and counseling to the community is essential.
Dry eye symptoms using the Ocular Surface Disease Index in Sweden: a short report from a pilot study
Authors: Roth Jenny , Nilsson Ida , Melin Jeanette , Macedo Antonio Filipe
Published: July 2022

The aim of this study was to investigate the prevalence of dry eye symptoms in the Swedish population using a web-based version of the ocular surface disease index (OSDI). 
A web-based version of the OSDI questions was implemented in an online form using a software developed by Artologik. The link to the form was distributed via Linnaeus University social media pages. Basic demographic information such as age, sex and county of residence was also collected.
A total of 404 complete responses were received, 303 respondents (75%) were females, the median age = 39 (interquartile range = 28-53) years, median OSDI-score = 19 (interquartile range = 9-32). Crude prevalence of dry eye symptoms (categories mild to severe) was 65% (95% CI = 62-75). The difference in prevalence between males and females was statistically significant (chi-square test, p = 0.007).
 
The current study found that the prevalence of dry eye symptoms among a sample of the Swedish population was 65%. These results highlight the need to investigate further the prevalence and risk factors for dry eye disease in the Swedish population.
Studi Karakteristik Termohidrolik Pada Kanal Pendingin Teras Reaktor SMART Menggunakan CFD Ansys Fluent
Authors:   Direktorat Perizinan Instalasi dan Bahan Nuklir - BAPETEN, Jakarta, Indonesia, Waluyo Agus , Septilarso Anggoro , Umar Efrizon
Published: July 2022

The Small Modular Reactor (SMR) type nuclear power plant is currently growing very rapidly by offering various kinds of safety features, both active and passive. One of the SMRs currently to be built and operated is the SMART (System-integrated Modular Advanced Reactor) reactor. The SMART reactor is designed to use conventional PWR fuel types but operates at a lower flow rate and core inlet temperature than conventional PWR. The existence of this basic difference needs to be a separate note for us in evaluating the safety of the SMART Reactor, especially for the thermohydraulic aspect. The thermohydraulic characteristics have been carried out previously using the MATRA code, however, the temperature distribution in the cooling sub channel is still unknown. Therefore, the purpose of this study is to calculate the temperature distribution in the cooling sub-channel on SMART. The program used in this study is CFD ANSYS. Ansys Fluent 2021 R1 Computational Fluid Dynamic (CFD) computer code was used to simulate coolant flow and heat transfer from fuel to coolant. The cooling sub channel was modeled consisting of four fuels with a diameter of 0.95 cm and a pitch of 1.26 cm in a rectangular arrangement surrounded by light water coolant. Based on the calculation, there is an increase in the average temperature of the coolant between the input and output sides of the coolant sub channel of 60 ℃, which is greater than the SMART reactor design. The fuel center and fuel cladding temperatures were calculated at 1100 ℃ and 350 ℃, respectively. This difference is caused by the modeling assumptions which is still far from the actual design. The model was assumed to consist of pure fuel and ignores the actual variations in fuel and fuel assembly. Keywords: SMART Reactor, CFD, Ansys Fluent, Thermal Hydraulic
nalisis Nilai CTDIvol pada Teknik Pemeriksaan Low Dose CT Scan (LDCT) Thorax Skrining Covid-19 Tanpa dan Dengan Penggunaan Sn-Filter
Authors:   Politeknik Kesehatan Kementerian Kesehatan Jakarta II, Jakarta Selatan, DKI Jakarta, Setiawan Iwan , Apriantoro Nursama Heru , Syarif Hidayat Eka Putra
Published: July 2022

Over the past 40 years, various CT technology innovations have been developed to reduce the radiation dose patients receive. Establishing an additional pre-patient filter, Sn-filter (tin filter), to complete the existing pre-patient filter (bow tie filter) has become one of the CT Scan manufacture’s concerns to provide the Low Dose CT Scan (LDCT) technique. LDCT technique with Sn-filter has been implemented in Hermina Depok hospital especially for CT thorax screening Covid-19 examination, as an early detection before patients receive the following elective procedure. This study aims to identify the results of CTDIvol between LDCT thorax screening Covid-19 examination with or without Sn-filter and its correlation to image noise. CTDIvol data was obtained by LDCT scanning into two groups of patients without or with Sn-filter. The average CTDIvol value LDCT without Sn-filter is 2.33 mGy and with Sn-filter is 1.47 mGy. The statistic of the independent sample t-test result revealed Sig (2-tailed) = 0.000 < 0.05, indicating a difference in the average CTDIvol value without or with Sn-filter. The noise level has obtained by LDCT scanning into three types of CT water phantom. The average noise level value LDCT without Sn-filter is 18.88%, and with Sn-filter 23.66%, the intermediate image noise level is increased by 4,78% using LDCT with Sn-filter. Keywords: low dose CT Scan, screening Covid-19, Sn-filter, CTDIvol, noise level
Analisis Kebutuhan Sistem Deteksi Radiasi terhadap Bahan Radioaktif di Luar Kendali Pengawasan
Authors:   Pusat Pengkajian Sistem dan Teknologi Pengawasan Instalasi dan Bahan Nuklir, Badan Pengawas Tenaga Nuklir, Huda Khoirul
Published: July 2022

The Need Analysis of Radiation Detection System for Radioactive Materials Out of Regulatory Control. Radioactive materials out of regulatory control (MORC) can threaten human life because they can misuse these materials for terrorism or other illegal acts. Therefore, must prevention of acts of terrorism using radioactive materials by preventing the emergence of MORC itself through nuclear security means, including installing radiation detection systems at borders and entrances to the country's territory. Therefore, it is necessary to know the installation points, and the number of detection devices installed to install the detection system. However, until now, there has been no analysis of the need to install the system in Indonesia. In this study, a qualitative analysis has been carried out using secondary data on the need for a radioactive material detection system in border areas and entrances to the country. The analysis results show the high demand for installation of the detection system and the vast gap between the number of detection devices currently available and those needed. Keywords: MORC, nuclear security of MORC, radiation detection system, RPM.