bluuebunny/crossref_metadata_2025 huggingface dataset:
Perov Fixed-Point Results on F-Contraction Mappings Equipped with Binary Relation
Authors: Din Fahim Ud , Din Muhammad , Ishtiaq Umar , Sessa Salvatore
Published: January 2023

The purpose of this article is to discuss some new aspects of the vector-valued metric space. The idea of an arbitrary binary relation along with the well-known F contraction is used to demonstrate the existence of fixed points in the context of a complete vector-valued metric space for both single- and multi-valued mappings. Utilizing the idea of binary relation, and with the help of F contraction, this work extends and complements some of the very recently established Perov-type fixed-point results in the literature. Furthermore, this work includes examples to justify the validity of the given results. During the discussion, it was found that some of the renowned metrical results proven by several authors using different binary relations, such as partial order, pre-order, transitive relation, tolerance, strict order and symmetric closure, can be weakened by using an arbitrary binary relation.
Recent Advances on the Fabrication of Antifouling Phase-Inversion Membranes by Physical Blending Modification Method
Authors: Geleta Tesfaye Abebe , Maggay Irish Valerie , Chang Yung , Venault Antoine
Published: January 2023

Membrane technology is an essential tool for water treatment and biomedical applications. Despite their extensive use in these fields, polymeric-based membranes still face several challenges, including instability, low mechanical strength, and propensity to fouling. The latter point has attracted the attention of numerous teams worldwide developing antifouling materials for membranes and interfaces. A convenient method to prepare antifouling membranes is via physical blending (or simply blending), which is a one-step method that consists of mixing the main matrix polymer and the antifouling material prior to casting and film formation by a phase inversion process. This review focuses on the recent development (past 10 years) of antifouling membranes via this method and uses different phase-inversion processes including liquid-induced phase separation, vapor induced phase separation, and thermally induced phase separation. Antifouling materials used in these recent studies including polymers, metals, ceramics, and carbon-based and porous nanomaterials are also surveyed. Furthermore, the assessment of antifouling properties and performances are extensively summarized. Finally, we conclude this review with a list of technical and scientific challenges that still need to be overcome to improve the functional properties and widen the range of applications of antifouling membranes prepared by blending modification.
Multi-Objective Optimization of Performance Indicators in Turning of AISI 1045 under Dry Cutting Conditions
Authors: Abbas Adel T. , Al-Abduljabbar Abdulhamid A. , El Rayes Magdy M. , Benyahia Faycal , Abdelgaliel Islam H. , Elkaseer Ahmed
Published: January 2023

In machining operations, minimizing the usage of resources such as energy, tools, costs, and production time, while maximizing process outputs such as surface quality and productivity, has a significant impact on the environment, process sustainability, and profit. In this context, this paper reports on the utilization of advanced multi-objective algorithms for the optimization of turning-process parameters, mainly cutting speed, feed rate, and depth of cut, in the dry machining of AISI 1045 steel for high-efficient process. Firstly, a number of experimental tests were conducted in which cutting forces and cutting temperatures are measured. Then the material removal rate and the obtainable surface roughness were determined for the examined range of cutting parameters. Next, regression models were developed to formulate the relationships between the process parameters and the four process responses. After that, four different multi-objective optimization algorithms, (1) Gray Wolf Optimizer (GWO) and (2) Weighted Value Gray Wolf Optimizer (WVGWO), (3) Multi-Objective Genetic Algorithm (MOGA), and (4) Multi-Objective Pareto Search Algorithm (MOPSA), were applied. The results reveal that the optimal running conditions of the turning process of AISI 1045 steel obtained by WVGWO are a feed rate of 0.050 mm/rev, cutting speed of 156.5 m/min, and depth of cut of 0.57 mm. These conditions produce a high level of material removal rate of 4460.25 mm3/min, in addition to satisfying the surface quality with a roughness average of 0.719 µm. The optimal running conditions were found to be dependent on the objective outcomes’ order. Moreover, a comparative evaluation of the obtainable dimensional accuracy in both dry and wet turning operations was carried out, revealing a minimal relative error of 0.053% maximum between the two turning conditions. The results of this research work assist in obtaining precise, optimal, and cost-effective machining solutions, which can deliver a high-throughput, controllable, and robust manufacturing process when turning AISI 1045 steel.
Microstructural Evolution and Mechanical Properties of Al-Si-Mg-Cu Cast Alloys with Different Cu Contents
Authors: Zhou Pengfei , Wang Dongtao , Nagaumi Hiromi , Wang Rui , Zhang Xiaozu , Li Xinzhong , Zhang Haitao , Zhang Bo
Published: January 2023

The mechanical properties of Al-Si-Mg-Cu cast alloys are heavily determined by Cu content due to the precipitation of relating strengthening precipitates during the aging treatment. In this study, the microstructures and mechanical properties of Al-9Si-0.5Mg-xCu (x = 0, 0.9, 1.5, and 2.1 wt.%) alloys were investigated to elucidate the effect of Cu content on the evolution of their mechanical properties. After T6 (480 °C + 6 h − 530 °C + 4 h, 175 °C + 10 h) treatment, Mg-rich and Cu-rich phases were dissolved in the matrix; the main aging-precipitates of the alloys change from the needle-like β″ phases in the base alloy to the granular Q′ phases in the 0.9Cu alloy, the granular Q′ phase in the 1.5Cu alloy, the granular Q′ phase, and θ′ platelets in the 2.1Cu alloy. The increase of Cu level results in difference of the type, number density, and morphology of the nanoscale precipitated phase. Because of precipitation strength, the yield strength was increased by 103–130 MPa depending on the Cu contents. The precipitation strengthening effect of the precipitates was quantitatively evaluated by the Orowan mechanism. The aging-treated Al-9Si-0.5Mg-2Cu alloy shows the good strength and ductility: yield strength 351 MPa, ultimate tensile strength 442 MPa, and elongation 8.4%. The morphologies of fracture surfaces of the alloys also were observed.
Recent Advances in Flexible Ultrasonic Transducers: From Materials Optimization to Imaging Applications
Authors: Ren Danyang , Yin Yonggang , Li Chiye , Chen Ruimin , Shi Junhui
Published: January 2023

Ultrasonic (US) transducers have been widely used in the field of ultrasonic and photoacoustic imaging system in recent years, to convert acoustic and electrical signals into each other. As the core part of imaging systems, US transducers have been extensively studied and achieved remarkable progress recently. Imaging systems employing conventional rigid US transducers impose certain constraints, such as not being able to conform to complex surfaces and comfortably come into contact with skin and the sample, and meet the applications of continuous monitoring and diagnosis. To overcome these drawbacks, significant effort has been made in transforming the rigid US transducers to become flexible and wearable. Flexible US transducers ensure self-alignment to complex surfaces and maximize the transferred US energy, resulting in high quality detection performance. The advancement in flexible US transducers has further extended the application range of imaging systems. This review is intended to summarize the most recent advances in flexible US transducers, including advanced functional materials optimization, representative US transducers designs and practical applications in imaging systems. Additionally, the potential challenges and future directions of the development of flexible US transducers are also discussed.
Evaluation of Two Different Preparation Protocols for MALDI-TOF MS Nontuberculous Mycobacteria Identification from Liquid and Solid Media
Authors: Pastrone Lisa , Curtoni Antonio , Criscione Giulia , Scaiola Francesca , Bottino Paolo , Guarrasi Luisa , Iannaccone Marco , Timke Markus , Costa Cristina , Cavallo Rossana
Published: January 2023

Nontuberculous mycobacteria (NTM) identification is essential for establishing the relevance of the isolate and for appropriate antimicrobial therapy. Traditionally, NTM identification is performed by using Line Probe Assays (LPA), a costly and time-consuming technique requiring trained personnel. MALDI-TOF MS is a promising tool for NTM identification, and its use is rapidly growing. We evaluated the newly introduced MBT Mycobacteria kit (MBT) and the MycoEx preparation protocol (Bruker Daltonics, Germany) for NTM MALDI-TOF MS identification using LPA results as a reference. Fifty NTM grown on 7H11 agar and MGIT broth were analyzed with both protocols using the Bruker Microflex® LT MALDI-TOF MS (Bruker Daltonics) instrument. MBT and MycoEx provided identification results in 97.0% and 95.0% of the cases, respectively. With both protocols, 100% of the provided results agreed with LPA with no registered mismatch. MBT achieved an elevated number of highly probable identifications (88.0% vs. 83.0%) and a higher reproducibility rate of correct results (86.6% vs. 75.8%) in comparison to MycoEx. This study provides results about MBT performance for liquid and solid media, underlining the strengths and weakness under different conditions. Our results suggest that MALDI-TOF MS could provide a great advantage for timely and cost-saving NTM identification with potential implications for patient outcome.
Natural Products from Leaves of the Ancient Iranian Medicinal Plant Echium amoenum Fisch. & C. A. Mey.
Authors: Jamnani Mehdi Jafari , Holmelid Bjarte , Vedeler Anni , Parsian Hoda Houshiar , Andersen Heidi Lie , Fossen Torgils
Published: January 2023

For several millennia, leaves of Echium amoenum Fisch. & C. A. Mey., an important Iranian medicinal plant with nutritional value as nutraceutical, have been used as tea for the treatment of several conditions, including inflammation. The nutritional value of intake of E. amoenum tea has mainly been correlated to its rich content of mainly water-soluble antioxidants. Although the entire plant is utilized, only natural products of the flowers have previously been thoroughly investigated. The rare natural products bis(3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl)-1-(3,4-dihydroxyphenyl)-6,7-dihydroxy-1,2-dihydronaphthalene-2,3-dicarboxylate, 4-Oxy-(E)-caffeoyl-2,3-dihydroxybutanoic acid methyl ester and 4-Oxy-(Z)-caffeoyl-2,3-dihydroxybutanoic acid methyl ester, in addition to the widely distributed compounds rosmarinic acid methyl ester and (E)-caffeic acid, were purified and characterized from leaves of Echium amoenum. The structures were determined by a combination of several 2D NMR spectroscopic techniques, circular dichroism spectroscopy and high-resolution mass spectrometry. The fact that bis(3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl)-1-(3,4-dihydroxyphenyl)-6,7-dihydroxy-1,2-dihydronaphthalene-2,3-dicarboxylate belongs to a rare group of natural products which have previously been patented for their significant anti-inflammatory activity may rationalize the traditional treatment of inflammations with E. amoenum.
Hemin-Modified Multi-Walled Carbon Nanotube-Incorporated PVDF Membranes: Computational and Experimental Studies on Oil–Water Emulsion Separations
Authors: Abdulazeez Ismail , Salhi Billel , Elsharif Asma M. , Ahmad Muhammad S. , Baig Nadeem , Abdelnaby Mahmoud M.
Published: January 2023

The separation of oil/water emulsions has attracted considerable attention for decades due to the negative environmental impacts brought by wastewater. Among the various membranes investigated for separation, polyvinylidene fluoride (PVDF) membranes have shown significant advantages of ease of fabrication, high selectivity, and fair pore distribution. However, PVDF membranes are hydrophobic and suffer from severe fouling resulting in substantial flux decline. Meanwhile, the incorporation of wettable substrates during fabrication has significantly impacted the membrane performance by lowering the fouling propensity. Herein, we report the fabrication of an iron-containing porphyrin (hemin)-modified multi-walled carbon nanotube incorporated PVDF membrane (HA-MWCNT) to enhance fouling resistance and the effective separation of oil-in-water emulsions. The fabricated membrane was thoroughly investigated using the FTIR, SEM, EDX, AFM, and contact angle (CA) analysis. The HA-MWCNT membrane exhibited a water CA of 62° ± 0.5 and excellent pure water permeance of 300.5 L/m2h at 3.0 bar (400% increment), in contrast to the pristine PVDF, which recorded a CA of 82° ± 0.8 and water permeance of 59.9 L/m2h. The hydrophilic HA-MWCNT membrane further showed an excellent oil rejection of >99% in the transmembrane pressure range of 0.5–2.5 bar and a superb flux recovery ratio (FRR) of 82%. Meanwhile, the classical molecular dynamics (MD) simulations revealed that the HA-MWCNT membrane had greater solvent-accessible pores, which enhanced water permeance while blocking the hydrocarbons. The incorporation of the hemin-modified MWCNT is thus an excellent strategy and could be adopted in the design of advanced membranes for oil/water separation.
Fabrication of Well-Aligned ZnO Nanorods with Different Reaction Times by Chemical Bath Deposition Method Applying for Photocatalysis Application
Authors: Wai Htet Su , Li Chaoyang
Published: January 2023

Zinc oxide nanorods were grown on an aluminum-doped zinc oxide seeds layer using the chemical bath deposition method. The effects of growth reaction time on the structural, optical, and photocatalytic properties of zinc oxide nanorods were investigated. It was clearly observed that the growth direction of zinc oxide nanorods were dependent on the crystallinity of the as-deposited aluminum-doped zinc oxide seed layer. The crystallinity of the obtained zinc oxide nanorods was improved with the increase in reaction times during the chemical bath deposition process. The mechanism of zinc oxide nanorod growth revealed that the growth rate of nanorods was influenced by the reaction times. With increasing reaction times, there were much more formed zinc oxide crystalline stacked growth along the c-axis orientation resulting in an increase in the length of nanorods. The longest nanorods and the high crystallinity were obtained from the zinc oxide nanorods grown within 5 h. The optical transmittance of all zinc oxide nanorods was greater than 70% in the visible region. Zinc oxide nanorods grown for 5 h showed the highest degradation efficiency of methyl red under ultraviolet light and had a high first-order degradation rate of 0.0051 min−1. The photocatalytic mechanism was revealed as well.
Structural Features of Monoethanolamine Aqueous Solutions with Various Compositions: A Combined Experimental and Theoretical Study Using Vibrational Spectroscopy
Authors: Legkov Sergey A. , Bondarenko Galina N. , Kostina Julia V. , Novitsky Eduard G. , Bazhenov Stepan D. , Volkov Alexey V. , Volkov Vladimir V.
Published: January 2023

In this work, we studied aqueous solutions of monoethanolamine (MEA), which are widely used to remove CO2 from flue and oil gases. This study combined experimental and theoretical methods of vibrational spectroscopy, using high-temperature infrared spectroscopy, quantum-chemical calculations of theoretical vibrational spectra, and structural electronic and energy characteristics of model structures. MEA has a propensity to form associations between various compositions and structures with water molecules, as well as those composed solely of water molecules. The structural and energy characteristics of such associates were analyzed in terms of their ability to interact and retain carbon dioxide. The influence of elevated temperatures and concentration of aqueous MEA solution on change in the structure of associates has also been investigated. An analysis of theoretical and experimental vibrational spectra allowed us to examine the IR spectra of MEA solutions, and identify the bands responsible for the formation of associates that would sorb CO2 well, but would delay its desorption from the solution.
Multifunctional Magnetic Nanocomposites: Innovative Processing and Applications
Authors: Kuncser Victor
Published: January 2023

Multifunctional magnetic nanocomposites are among those heterogeneous nanosized systems where at least one phase component is magnetic and can act as an intermediate of either the actuation or the response of the overall system. The main advantage of heterogeneous nanosystems is the possibility of combining and inter-influencing the electronic properties of constituent interfaced nanophases. Consequently, unique physico-chemical properties of the hybrid materials of interest in various applications can be obtained. This Special Issue of Nanomaterials highlights the most advanced processing and characterization tools of some multifunctional magnetic nanocomposites and heterogeneous systems of interest in various applications, from biomedicine to sensoristics and energy-saving materials.
Nanomaterials for Drug Delivery and Cancer Therapy
Authors: Nicoletta Fiore Pasquale , Iemma Francesca
Published: January 2023

In recent decades, the interest in nanomaterials has grown rapidly for their applications in many research fields, including drug delivery and cancer therapy [...]
Ionized Magnesium: Interpretation and Interest in Atrial Fibrillation
Authors: Bouillon-Minois Jean-Baptiste , Khaled Louisa , Vitte Florence , Miraillet Ludovic , Eschalier Romain , Jabaudon Matthieu , Sapin Vincent , Derault Lucas , Kahouadji Samy , Brailova Marina , Durif Julie , Schmidt Jeannot , Moustafa Fares , Pereira Bruno , Futier Emmanuel , Bouvier Damien
Published: January 2023

Background: Magnesium (Mg) is often used to manage de novo atrial fibrillation (AF) in the emergency department (ED) and intensive care unit (ICU). Point of care measurement of ionized magnesium (iMg) allows a rapid identification of patients with impaired magnesium status, however, unlike ionized calcium, the interpretation of iMg is not entirely understood. Thus, we evaluated iMg reference values, correlation between iMg and plasmatic magnesium (pMg), and the impact of pH and albumin variations on iMg levels. Secondary objectives were to assess the incidence of hypomagnesemia in de novo AF. Methods: A total of 236 emergency department and intensive care unit patients with de novo AF, and 198 control patients were included. Reference values were determined in the control population. Correlation and concordance between iMg and pMg were studied using calcium (ionized and plasmatic) as a control in the whole study population. The impact of albumin and pH was assessed in the discordant iMg and pMg values. Lastly, we assessed the incidence of ionized hypomagnesemia (hypoMg) among de novo AF. Results: The reference range values established in our study for iMg were: 0.48–0.65 mmol/L (the manufacturers were: 0.45–0.60 mmol/L). A strong correlation was observed between pMg and iMg (r = 0.85), but, unlike for calcium values, there was no significant impact of pH and albumin in iMg/pMg interpretation. The incidence of hypoMg among de novo AF patients was 8.5% (12.7% using our ranges). When using our ranges, we found a significant link (p = 0.01) between hyopMg and hypokalemia. Conclusion: We highlight the need for more accurate reference range values of iMg. Furthermore, our results suggest that blood Mg content is not identical to that of calcium. The incidence of ionized hypomagnesemia among de novo AF patients in our study is 8.5%.
Association of Dietary α-Carotene and β-Carotene Intake with Low Cognitive Performance in Older Adults: A Cross-Sectional Study from the National Health and Nutrition Examination Survey
Authors: Zhong Qiya , Sun Wen , Qin Yao , Xu Huadong
Published: January 2023

This study aims to examine the relationships of dietary α-carotene and β-carotene intake with cognitive function. The data were selected from the National Health and Nutrition Examination Survey (NHANES) 2011–2014. A total of 2009 participants were included in this analysis. Dietary α-carotene and β-carotene intake were averaged by two 24-h dietary recalls. The Consortium to Establish a Registry for Alzheimer’s Disease Word Learning subset (CERAD W-L), Animal Fluency Test (AFT), and Digit Symbol Substitution Test (DSST) were used to evaluate cognitive function. Logistic regression and restricted cubic spline models were applied to explore the associations of dietary α-carotene and β-carotene intake with cognitive performance. After adjusting for all confounding factors, compared with individuals in the lowest quartile of β-carotene dietary intake, those in the highest quartile had lower risks of both CERAD W-L decline [odds ratio (OR) = 0.63, 95% confidence interval (CI): 0.44–0.90] and AFT decline (OR = 0.66, 95% CI: 0.47–0.94). In addition, the third quartile of β-carotene dietary intake had a significantly decreased risk of lower DSST (OR = 0.67, 95% CI: 0.48–0.83). Compared with the lowest quartile of α-carotene intake, the OR of AFT decline in the highest intake quartile was 0.66 (95% CI: 0.46, 0.94). For males, both dietary α-carotene and β-carotene intake were associated with a decreased risk of AFT decline (OR = 0.42, 95% CI: 0.25–0.71; OR = 0.51, 95% CI: 0.30–0.85, respectively). For females, dietary α-carotene intake was associated with a decreased risk of CERAD W-L decline (OR = 0.55, 95% CI: 0.33–0.91) and dietary β-carotene intake was associated with decreased risks of both CERAD W-L and AFT decline (OR = 0.37, 95% CI: 0.21–0.64; OR = 0.58, 95% CI: 0.37–0.91, respectively). Our results suggested that higher dietary α-carotene and β-carotene intake had inverse effects on cognitive function decline among older adults.
Therapies for COVID-19-Related Persistent Olfactory Disorders: One of the Good Fruits of the Pandemic
Authors: Saussez Sven , Vaira Luigi Angelo , De Riu Giacomo , Lechien Jérome R.
Published: January 2023

At the beginning of 2021, the scientific community realized the burden of COVID-19-related persistent olfactory disorders (ODs). The percentage of those infected with COVID-19 who developed severe and persistent ODs [1–3] with devastating effects on their quality of life was 5 to 40% [4,5].
Extracellular Non-Coding RNAs in Cardiovascular Diseases
Authors: Jiapaer Zeyidan , Li Chengyu , Yang Xinyu , Sun Lingfei , Chatterjee Emeli , Zhang Lingying , Lei Ji , Li Guoping
Published: January 2023

Cardiovascular diseases (CVDs) remain the world’s leading cause of death despite the best available healthcare and therapy. Emerging as a key mediator of intercellular and inter-organ communication in CVD pathogenesis, extracellular vesicles (EVs) are a heterogeneous group of membrane-enclosed nano-sized vesicles released by virtually all cells, of which their RNA cargo, especially non-coding RNAs (ncRNA), has been increasingly recognized as a promising diagnostic and therapeutic target. Recent evidence shows that ncRNAs, such as small ncRNAs, circular RNAs, and long ncRNAs, can be selectively sorted into EVs or other non-vesicular carriers and modulate various biological processes in recipient cells. In this review, we summarize recent advances in the literature regarding the origin, extracellular carrier, and functional mechanisms of extracellular ncRNAs with a focus on small ncRNAs, circular RNAs, and long ncRNAs. The pathophysiological roles of extracellular ncRNAs in various CVDs, including atherosclerosis, ischemic heart diseases, hypertension, cardiac hypertrophy, and heart failure, are extensively discussed. We also provide an update on recent developments and challenges in using extracellular ncRNAs as biomarkers or therapeutical targets in these CVDs.
In Silico Quantification of Intersubject Variability on Aerosol Deposition in the Oral Airway
Authors: Borojeni Azadeh A. T. , Gu Wanjun , Asgharian Bahman , Price Owen , Kuprat Andrew P. , Singh Rajesh K. , Colby Sean , Corley Richard A. , Darquenne Chantal
Published: January 2023

The extrathoracic oral airway is not only a major mechanical barrier for pharmaceutical aerosols to reach the lung but also a major source of variability in lung deposition. Using computational fluid dynamics, deposition of 1–30 µm particles was predicted in 11 CT-based models of the oral airways of adults. Simulations were performed for mouth breathing during both inspiration and expiration at two steady-state flow rates representative of resting/nebulizer use (18 L/min) and of dry powder inhaler (DPI) use (45 L/min). Consistent with previous in vitro studies, there was a large intersubject variability in oral deposition. For an optimal size distribution of 1–5 µm for pharmaceutical aerosols, our data suggest that >75% of the inhaled aerosol is delivered to the intrathoracic lungs in most subjects when using a nebulizer but only in about half the subjects when using a DPI. There was no significant difference in oral deposition efficiency between inspiration and expiration, unlike subregional deposition, which shows significantly different patterns between the two breathing phases. These results highlight the need for incorporating a morphological variation of the upper airway in predictive models of aerosol deposition for accurate predictions of particle dosimetry in the intrathoracic region of the lung.
Optimal Design of Segmented Planar Imaging System Based on Rotation and CLEAN Algorithm
Authors: Ming Zhizi , Liu Yang , Li Shanchuang , Zhou Mengchen , Du Haoran , Zhang Xiaochun , Zuo Yong , Qiu Jifang , Wu Jian , Gao Lu , Zhang Ze
Published: January 2023

We propose a parity-baseline segmented planar imaging method with more frequency components by changing different baseline selection to achieve better imaging in the rotational process. A theoretical model of the parity-baseline segmented planar imaging system with rotational operation is built to analyze the imaging effect. The simulation results show that the imaging quality of the parity-baseline segmented planar imaging system has an approximately 20% increase by rotation compared with the conventional system. In addition, the CLEAN algorithm in radio astronomy imaging is also applied to the parity-baseline segmented planar imaging system, and the image quality is further improved by 55%. Such a new imaging method holds great potential toward astronomical observation and detection.
3 W Continuous-Wave Room Temperature Quantum Cascade Laser Grown by Metal-Organic Chemical Vapor Deposition
Authors: Fei Teng , Zhai Shenqiang , Zhang Jinchuan , Lu Quanyong , Zhuo Ning , Liu Junqi , Wang Lijun , Liu Shuman , Jia Zhiwei , Li Kun , Sun Yongqiang , Guo Kai , Liu Fengqi
Published: January 2023

In this article, we report a high-performance λ ~ 4.6 μm quantum cascade laser grown by metal-organic chemical vapor deposition. Continuous wave power of 3 W was obtained from an 8 mm-long and 7.5 μm wide coated laser at 285 K. The maximum pulsed and CW wall-plug efficiency reached 15.4% and 10.4%, respectively. The device performance shows the great potential of metal-organic chemical vapor deposition growth for quantum cascade material and devices.
Short-Term Effects of Trans-Cinnamic Acid on the Metabolism of Zea mays L. Roots
Authors: López-González David , Bruno Leonardo , Díaz-Tielas Carla , Lupini Antonio , Aci Meriem Miyassa , Talarico Emanuela , Madeo Maria Letizia , Muto Antonella , Sánchez-Moreiras Adela M. , Araniti Fabrizio
Published: January 2023

trans-Cinnamic acid is a phenolic compound widely studied in plant metabolism due to its importance in regulating different plant processes. Previous studies on maize plants showed that this compound could affect plant growth and causes metabolic changes in the leaves when applied. However, its effects on root metabolism are not well known. This study analyses the short-term effect of trans-cinnamic acid on the morphology of vascular bundle elements and metabolism in maize roots. At short times (between 6 and 12 h), there is a reduction in the content of many amino acids which may be associated with the altered nitrogen uptake observed in earlier work. In addition, the compound caused an alteration of the vascular bundles at 48 h and seemed to have changed the metabolism in roots to favor lignin and galactose synthesis. The results obtained complement those previously carried out on maize plants, demonstrating that in the short term trans-cinnamic acid can trigger stress-coping processes in the treated plants.
Triterpene Derivatives from Garcinia oligantha and Their Anti-Cancer Activity
Authors: Peng Xiaohui , Wang Chao , Hou Yonglian , Tian Jiamei , Fan Xiaojie , Li Dahong , Hua Huiming
Published: January 2023

Phytochemical investigations of leaves and twigs from Garcinia oligantha Merr. resulted in the isolation of five undescribed triterpene derivatives (1–5) and six known analogs (6–11). Their structures were determined based on extensive spectroscopic data and high-resolution mass spectra analyses. Compounds 1–11 were tested for their in vitro cytotoxicity against three human cancer cell lines (HeLa, HepG-2, and MCF-7). Compounds 1, 2, 8, and 11 exhibited broad and significant cytotoxicity against the tested cell lines with IC50 values ranging from 5.04 to 21.55 μM. Compounds 5 and 9 showed cytotoxicity against HeLa and MCF-7 with IC50 values ranging from 13.22 to 19.62 μM. The preliminary structure–activity relationship for the 11 isolated compounds is also discussed.
Changes in the Composition of Biologically Active Compounds during the Ripening Period in Fruit of Different Large Cranberry (Vaccinium macrocarpon Aiton) Cultivars Grown in the Lithuanian Collection
Authors: Šedbarė Rima , Pašakinskienė Izolda , Janulis Valdimaras
Published: January 2023

In our investigation, we evaluated the content of chlorogenic acid, proanthocyanidins, anthocyanins, flavonols, triterpenoids, and phytosterols in cranberry fruit extracts of the cultivars ‘Baifay’, ‘Early Black’, ‘Howes’, ‘Pilgrim’, ‘Red Star’, and ‘Stevens’ grown in Lithuania, as well as changes in the antioxidant activity in extracts of fruit samples of these cultivars during the period of berry maturation. The highest amount of proanthocyanidins (8.87 ± 0.57 mg EE/g EE) and flavonols (3688.52 ± 22.85 µg/g) was determined in cranberries of the cultivar ‘Howes’ harvested on 12 August. Remarkably, the highest anthocyanins content (9628.62 ± 266 µg/g) was determined in cranberries of the cultivar ‘Howes’ harvested on 22 October. The study showed that the content of phytochemical compounds in cranberries varied between 12 August and 22 October; the content of proanthocyanidins decreased by a factor of about 2, the content of chlorogenic acid decreased by a factor of about 1.3, the content of flavonols decreased by a factor of about 2, and the content of anthocyanins increased by 27 to 450 times. A strong correlation was found between the total proanthocyanidin content of cranberry fruit extracts and their in vitro antiradical and reducing activity (r = 0.781 and 0.726, respectively, p < 0.001). The data of our study detail the accumulation of the phytochemical composition of biologically active compounds in cranberry samples during the stages of maturity, therefore these data are significant for the assessment of harvest time of cranberry and can be applied to select cranberry cultivars for further cultivation in Lithuanian climatic conditions.
The Effect of Transparent Conducting Oxide Films on WO3-Based Electrochromic Devices with Conducting Polymer Electrolytes
Authors: Au Benedict Wen-Cheun , Chan Kah-Yoong , Thien Gregory Soon How , Yeoh Mian-En , Sahdan Mohd Zainizan , Murthy Hanabe Chowdappa Ananda
Published: January 2023

Over the past few decades, electrochromism has been a prominent topic in energy-saving applications, which is based on the mechanism of altering the optical transmittance of EC materials under the effect of a small applied voltage. Thus, tungsten oxide (WO3) is a significant chemical compound typically applied in electrochromic devices (ECDs) as it is responsible for the optical transmittance variation. In this work, the WO3 films were produced through a sol–gel spin-coating method. The effect of various transparent conducting oxides (TCOs, which are indium-doped tin oxide (ITO), fluorine-doped tin oxide (FTO) glass substrates, and aluminum-doped zinc oxide (AZO)) was investigated in the construction of ECDs. Based on a conducting polymer polypyrene carbonate electrolyte, ITO and aluminum-doped zinc oxide (AZO)-coated glasses were also examined as counter electrodes. The electrode combination employing FTO and ITO as the TCO and counter electrode, respectively, exhibited the most significant coloration efficiency of 72.53 cm2/C. It had coloring and bleaching transmittance of 14% and 56%, respectively, with a large optical modulation of 42%. In addition to that, ECDs with the AZO counter electrode have the advantage of lower intercalation charges compared to ITO and FTO. Hence, this research offers a new avenue for understanding the role of common TCO and counter electrodes in the development of WO3-based ECDs with conducting polymer electrolytes.
New Generation of SF6-Free Medium-Voltage Switchgear for the Electrical Network: Stability and Toxicity Studies of Trans-1,1,1,4,4,4-Hexafluorobut-2-ene with N2 Gas Mixture
Authors: Alonso Maria Luz , Espinazo Ane , Alonso Rosa Maria , Lombraña Jose Ignacio , Izcara Jesús , Izaguirre Josu
Published: January 2023

Binary gas mixture of N2 and trans-1,1,1,4,4,4-hexafluorobut-2-ene (HFO4E) is presented as an alternative to SF6 in medium-voltage electrical equipment. Its stability was tested under different conditions. No change was observed in the gas mixture after a permanent AC voltage of 30 kV applied for two years or during the making operations with a standard load-break switch. The same behavior was obtained under dielectric tests, electrical arcs and temperature rise tests according to the IEC 62271-1:2011 standard. For all of these conditions, the concentration of HFO4E remains practically unchanged; there is no impact on the insulation properties of the system and the degradation products formed would not affect the health and the environment if there were leaks. In these studies, gas mixtures samples were analyzed by a validated methodology based on gas chromatography coupled to mass spectrometry and thermal conductivity detectors. Finally, an OECD TG 403 acute inhalation toxicity test was also carried out with the gas mixture aged after the mentioned making operations. None of the mice used in the toxicity test were affected after 4 h of exposition to an ambient air with 30,000 ppmv of the gas mixture.
Characteristics of Bauxite Residue–Limestone Pellets as Feedstock for Fe and Al2O3 Recovery
Authors: Kar Manish Kumar , Safarian Jafar
Published: January 2023

Experimental research was carried out to produce pellets from bauxite residue for the further extraction of iron and alumina. Bauxite residue and limestone with three different mixture compositions were pelletized experimentally via agglomeration followed by drying and sintering at elevated temperatures. X-Ray diffraction (XRD) and scanning electron microscopy (SEM) were used for the phase and microstructural analysis, respectively. Tumble, abrasion, and breaking load tests were applied to determine the strength of the pellets. For measurement of porosity and surface area, mercury porosimetry and BET surface area methods were applied. It was found that at 1100 °C sintering temperature, all the three sintered pellet compositions have a moderate porosity and low strength, but the reverse result was found when 1200 °C sintering temperature was applied. Moreover, for the pellets sintered at 1150 °C high strength and proper porosities were obtained. In the sintered pellets, iron present in form of brownmillerite (Ca2Fe1.63Al0.36O5), srebrodolskite (Ca2Fe2O5), and fayalite (Fe2SiO4), while alumina present mostly in gehlenite (Ca2Al2SiO7) and little fraction in mayenite (Ca12Al14O33) and brownmillerite phases. The identified phases are the same for of the three pellets, however, with variations in their quantities. Porosity and mechanical properties of pellets are inversely related with both varying sintering temperature and composition. It was found that with more CaCO3 use in pelletizing, higher porosity is obtained. However, with increasing sintering temperature the strength of the pellets increases due to clustering of particles, while porosity decreases.
How a Humbler Science Becomes a Better Science
Authors: Lumbreras Sara , Gismera Laura , Oviedo Lluis
Published: January 2023

Giving humility a key role in scientific practice and communication would improve its objective social function—that is, the production of knowledge about our world and its application to the improvement of the human condition—and its public acceptance. This article reviews the limits of science arising from systemic, epistemic, methodological, and individual limitations and links them to the phenomena in scientific practice that they originate from. The reflection invites us to consider science from the point of view of its limits in situations where there is difficulty in reaching a consensus but also when a consensus has indeed been achieved. Science and technology reflect who we are as individuals and as a society and inherit both our virtues and weaknesses. Humility is the key to getting technoscience that brings us closer to the truth and helps us advance toward improving the human condition. Humbler science becomes a better science.
An Approach to Assess the Water Resources Reliability and Its Management
Authors: Żywiec Jakub , Szpak Dawid , Piegdoń Izabela , Boryczko Krzysztof , Pietrucha-Urbanik Katarzyna , Tchórzewska-Cieślak Barbara , Rak Janusz
Published: January 2023

One of the factors limiting the possibility of the development of urban agglomerations is access to drinking water. Due to progressive climate change, the available water resources are limited. The paper proposes new indicators of limiting the development of agglomerations related to the availability of water resources and the production capacity of water treatment plants, a method for assessing the diversification of water resources (using the Pielou index), and a water loss balance was prepared based on International Water Association (IWA) standards. On the basis of the obtained results, the potential increase in the number of inhabitants indicators (∆PR, ∆PP) and the time for the development of agglomeration indicators (TR, TP), the directions of development of the studied agglomerations in terms of the possibility of water supply were indicated. The main problems were reducing the amount of water losses, appropriate management of the migration policy of the population, and the necessity to look for alternative sources of water.
Level of Activity Changes Increases the Fatigue Life of the Porous Magnesium Scaffold, as Observed in Dynamic Immersion Tests, over Time
Authors: Putra Risky Utama , Basri Hasan , Prakoso Akbar Teguh , Chandra Hendri , Ammarullah Muhammad Imam , Akbar Imam , Syahrom Ardiyansyah , Kamarul Tunku
Published: January 2023

In the present study, the effects of human physiological activity levels on the fatigue life of a porous magnesium scaffold have been investigated. First, the dynamic immersion and biomechanical testing are carried out on a porous magnesium scaffold to simulate the physiological conditions. Then, a numerical data analysis and computer simulations predict the implant failure values. A 3D CAD bone scaffold model was used to predict the implant fatigue, based on the micro-tomographic images. This study uses a simulation of solid mechanics and fatigue, based on daily physiological activities, which include walking, running, and climbing stairs, with strains reaching 1000–3500 µm/mm. The porous magnesium scaffold with a porosity of 41% was put through immersion tests for 24, 48, and 72 h in a typical simulated body fluid. Longer immersion times resulted in increased fatigue, with cycles of failure (Nf) observed to decrease from 4.508 × 1022 to 2.286 × 1011 (1.9 × 1011 fold decrease) after 72 hours of immersion with a loading rate of 1000 µm/mm. Activities played an essential role in the rate of implant fatigue, such as demonstrated by the 1.1 × 105 fold increase in the Nf of walking versus stair climbing at 7.603 × 1011 versus 6.858 × 105, respectively. The dynamic immersion tests could establish data on activity levels when an implant fails over time. This information could provide a basis for more robust future implant designs.
The Impacts of Traditional Ecological Knowledge towards Indigenous Peoples: A Systematic Literature Review
Authors: Mohd Salim Jamilah , Anuar Siti Nursyadiq , Omar Khatijah , Tengku Mohamad Tengku Rozaina , Sanusi Nur Azura
Published: January 2023

Indigenous peoples are groups with different cultural and social characteristics that share inherited ties to their homeland and natural resources. They have their own understanding and cultural experience that amounts to traditional ecological knowledge. The aim of this study is to identify the impacts of traditional ecological knowledge on indigenous people. Two main databases, namely Web of Science and Scopus, were used to conduct a systematic literature review. From the findings and analysis, two themes and eleven sub-themes were identified. The first theme is economic activities, including six sub-themes: sources of income, employment opportunities, offering products to vendors or buyers, providing market value, providing low treatment cost, and providing opportunities to develop micro-enterprises. The second theme is health, with five sub-themes: supporting food security, harvesting country food, food or plant benefits, perceived health or medicinal purposes, and livelihoods of the indigenous people. In conclusion, traditional knowledge can play an important role in contributing to the livelihoods of indigenous people. In general, traditional knowledge can help indigenous people to improve their quality of life, especially those who rely on natural resources to survive, by offering secure and supplemented food, for instance, as well as a source of earnings, crucial for food security during hard times. Additionally, traditional knowledge of wild edible and medicinal plants can play a significant role in a community’s capacity to remain resilient and be preserved for future generations.
Influence of Day and Night Temperature and Radiation Intensity on Growth, Quality, and Economics of Indoor Green Butterhead and Red Oakleaf Lettuce Production
Authors: Tarr Sean T. , Valle de Souza Simone , Lopez Roberto G.
Published: January 2023

Lettuce (Lactuca sativa) is among the most consumed vegetables worldwide and is primarily field-grown; however, indoor agriculture enables year-round, precise production. Through precise manipulation of the mean daily temperature (MDT) and photosynthetic photon flux density (PPFD), crop color, morphology, and yield can be altered. Therefore, we quantified how MDT and PPFD interact and developed models predicting yield and economic viability. Eleven days after sowing, green butterhead lettuce ‘Rex’ and red oakleaf lettuce ‘Rouxaï RZ’ were transplanted into six deep-flow hydroponic tanks with day/night and MDTs of 22/15 °C (20 °C), 25/18 °C (23 °C), or 28/21 °C (26 °C), under light-emitting diodes providing a low or high PPFD of 150 or 300 µmol·m−2·s−1 for 17-h·d−1. As PPFD increased, shoot fresh mass (SFM) of ‘Rex’ increased by 29% (33.4 g). SFM of ‘Rouxaï RZ’ and shoot dry mass (SDM) of both cultivars was influenced by the interaction of MDT and PPFD. The greatest ‘Rouxaï RZ’ SFM (158.8 g) and SDM (6.42 g) were recorded at >20 °C MDT under the high PPFD; the lowest SFM (76.0 g) and SDM (3.17 g) occurred at 20 °C under the low PPFD. Similarly, ‘Rex’ SDM was greatest (7.36 g) and lowest (3.78 g) under the aforementioned MDTs and PPFDs. Increasing from the low to high PPFD increased tipburn incidence on ‘Rouxaï RZ’ from 0 to 25% and ‘Rex’ from 47 to 100%. ‘Rouxaï RZ’ had darker yellow-red foliage at lower MDTs under the high PPFD. A high MDT and low PPFD resulted in a lighter green. Finally, for the greatest SFM, while reducing energy costs as interpreted from the economic analysis, we recommend growing ‘Rex’ and ‘Rouxaï RZ’ under a PPFD of 150 and 300 µmol·m−2·s−1, respectively, at an MDT of 23 to 26 °C depending on the cost of temperature control.
Self-Consistency Equations for Composite Operators in Models of Quantum Field Theory
Authors: Pismak Yury , Pismensky Artem
Published: January 2023

The technique of functional Legendre transforms is used to develop an effective method for calculating the characteristics of critical phenomena in quantum field theory models in the Euclidean space of dimension d. Based on the diagrammatic representation of the second Legendre transform in the theory with a cubic interaction potential, the construction of self-consistent equations is carried out, the solution of which makes it possible to find the dimensions not only of the main fields, but also of the quadratic on the composite operators within the 1/n-expansion. Application of the proposed methods in the model F has given the opportunity to calculate in the main approximation by 1/n the anomalous dimensions of both scalar and tensor composite operators quadratic on the fields ϕ. For them, as functions of the spatial dimension d, we obtained explicit analytical expressions in the form of relations of two polynomials with integer coefficients.
Risks of Cardiac Arrhythmia Associated with COVID-19 Vaccination: A Systematic Review and Meta-Analysis
Authors: Abutaleb Mohammed H. , Makeen Hafiz A. , Meraya Abdulkarim M. , Alqahtani Saad S. , Al-Mass Bayan Ibrahim , Aljazaeri Reaam Omar , Alhazmi Bushra Dhuhayyan , Kalakattawi Afnan Mohammed Noor , Alajam Ahmed Ali
Published: January 2023

This systematic review and meta-analysis aimed to summarize the current evidence regarding the association between coronavirus disease 2019 (COVID-19) vaccination and the risk of cardiac arrhythmia. MEDLINE, via PubMed and OVID, Scopus, CENTRAL, and Web of Science were searched using the relevant keywords to identify the relevant citations. Comprehensive Meta-analysis and Review Manager 5.4.1 were used for all the statistical analyses. Seventeen studies (n = 567,033,087 patients) were included. The pooled analysis showed that the incidence of cardiac arrhythmia post-COVID-19 vaccination with Pfizer, Moderna, AstraZeneca, CoronaVac, and Sinopharm was 0.22%, 95% CI: (0.07% to 0.66%), 0.76%, 95% CI: (0.04% to 12.08%), 0.04%, 95% CI: (0.00% to 0.98%), 0.01%, 95% CI: (0.00% to 0.03%), and 0.03%, 95% CI: (0.00% to 18.48%), respectively. Compared to CoronaVac, Pfizer, Moderna, AstraZeneca, and Sinopharm had a higher incidence ratio rate (IRR; 22-times, 76-times, 4-times, and 3-times higher), respectively. Likewise, Pfizer, Moderna, and AstraZeneca showed a higher IRR than Sinopharm (7.3-times, 25.3-times, and 1.3-times higher). The current evidence shows that the incidence rate (IR) of cardiac arrhythmia post-COVID-19 vaccination is rare and ranges between 1 and 76 per 10,000. mRNA vaccines were associated with a higher IR of arrhythmia compared to vector-based vaccines. Inactivated vaccines showed the lowest IR of arrhythmia.