bluuebunny/crossref_metadata_2025 huggingface dataset:
Integrated marine monitoring for drilling discharges under mesotidal forcing
Authors: Makarynskyy О. , Makarynska D.
Published: June 2019

There is a range of hydrocarbon exploration and extraction industrial project activities taking place on the North West Shelf of the Australian Continent. The shelf is a diverse and important marine ecosystem, with a number of globally significant shallow coral reefs and marine protected areas, which are vital for survival of threatened and protected species. Some of the mentioned exploration and extraction activities, such as offshore drilling, may be permitted within few kilometres away from sensitive habitats extant near a project resource extraction area. The habitats may in some cases be presented by submerged shoal ecosystems of high biodiversity and thus high environmental/ecological value, due to the presence of either or both benthic biota and fish assemblages. As part of an environmental assessment program for the industrial activities, some of the offshore exploration operators examine the effects of drilling discharges on the marine ambience. This study describes such an assessment. For the assessment, a novel integrated marine monitoring approach was conceptually designed; the program was then executed in the field using bottom-mounted equipment and a remotely operated underwater vehicle with sensors mounted on it. This study focuses on assessing the wind conditions in the project area, sea level and current velocities, in situ water temperature, salinity, turbidity and acoustic echo intensity, over several stages of the drilling operations while the drilling cuttings and muds were discharged into the water column. The collected during the austral autumn months of April and May winds showed prevailing east-southeaserlies, which is aligned well with the general understanding of wind climatology of the area. Importantly, stronger than usual winds may have a defining impact on current speeds and directions, with the current speeds enhanced by such winds. On these occasions the water transporting a discharge material may pushed towards the sensitive habitat present in the area. Normally though the hydrodynamics in the project area are dominated by semi-diurnal tides. Both vertical current velocity and water temperature distributions indicated the presence of three layers within the water column over the project site. The vertical distribution of water salinity was rather homogenous throughout the entire water column. The monitored by an optical instrument turbidity and acoustic echo intensity from an ADCP (acoustic Doppler current profiler) showed that tracing discharge plumes with a remotely operated underwater vehicle is a viable technique, which could be implemented at other locations. Such independent parameters though need a thorough cross-calibration and inter-validation for the results to be fully understood.
Results of adaptation and verification of the coupled numerical models set for predicting the variation of oceanographic features in the North-Western part of the Black Sea
Authors: Kushnir D. V. , Tuchkovenko Yu. S. , Popov Yu. I.
Published: June 2019

In 2014 Ukraine lost the Ukrainian National Automated System of Marine Forecasting for the Black Sea that was created and operated at the premises of Marine Hydrophysical Institute of the National Academy of Sciences of Ukraine located in the Crimea. Within the framework of research works aimed at establishing a new marine forecasting system a possibility of employing the internationally acclaimed set of coupled numerical models Delft3D-FLOW + SWAN (the Simulating WAves Nearshore) for operational forecasting of the short-term (5 to 10 days) spatio-temporal variability of oceanographic features in the Ukrainian part of the Sea of Azov and the Black Sea Basin is considered. To ensure operation of the models set in the forecasting mode it was suggested to use a prediction of variability of meteorological characteristics at the air-sea interface obtained with the help of the numerical weather forecast model GFS (Global Forecast System). This paper presents the results of verification of Delft3D-FLOW and SWAN numerical models which were adapted to the conditions of the North-Western part of the Black Sea and its Odesa area in the version of meteorological data (fields of wind speed and direction, atmospheric pressure) assimilation from the GFS forecast archive. A technique of telescoping the spatial curvilinear computational grids with different resolution capacity was used in the process of models set adaptation to the conditions of the prognostic area. The models were verified by comparing modelling results with observational data on sea level variability in the ports of Odesa area of the North-Western part of the Black Sea (Chornomorsk, Odesa, Yuzhnyi), as well as with data on wind speed and direction, drift currents and characteristics of wind-induced waves recorded over the studied periods by the gauges of stationary hydrometeorological buoy which was mounted in the Bay of Odessa. Based on the analysis of the results of verification of coupled numerical models Delft3D-FLOW + SWAN set it was concluded that the set of coupled models has good prospects of being used in the system of operational forecasting of the variability of oceanographic parameters of the sea environment in the Ukrainian part of the Sea of Azov and the Black Sea Basin in the version of assimilation of meteorological information obtained from the GFS global forecast model.
Metodologia ativa no treino de sutura: o uso do EVA na construção de maquete de sutura artesanal
Authors: De Oliveira Gustavo
Published: June 2019

This article aims to illustrate the practice of the active methodology learning in veterinary medicine education. The presentation of a low cost and feasible handmade model for the improvement of the suture technique for training veterinary surgeons. Research carried out at the Montes Belos University (UniMB) - São Luís de Montes Belos, Goiás - at the undergraduate degree in Veterinary Medicine. This technique of suture studies and improvement is a scientific continuity of the research of the use of Scientific Methodology and how such educational tool improves and molds a professional with greater qualification and scientific ability.
Metodologia ativa na educação em medicina veterinária
Authors: De Oliveira Gustavo
Published: June 2019

This article aims to investigate the concept of active learning methodologies and its application in the course of veterinary medicine, Montes Belos Universidade (UniMB) - São Luís de Montes Belos, Goiás. The discussion here presented is based on the theoretical composition of the studies by Borges and Alencar (2014) and some education theorists who form part of this teaching methodology, such as Dewey, Vygotsky and Ausubel, and Bauman (2007) for socio-historical educational contextualization
Encarceramento intestinal em forame epiplóico: Relato de caso em equino
Authors: Freitas Dilma
Published: June 2019

The epiplastic foramen is a natural opening in the thoracic cavity that communicates with the abdominal cavity, located dorsally to the cleft of the liver, contacting the caudal vena cava, portal vein, pancreas, hepatoduodenal ligament and with the small intestine loops. Horses diagnosed with intestinal loop incarceration in the epiplastic foramen require surgical treatment, with a prognosis of being reserved to unfavorable, and the ileum is the intestinal segment most affected in this disease. In addition, because of a strangulative process, the animal shows signs of abdominal discomfort called colic and enterogastric reflux, but clinical signs are variable. Some animals in the palpation present palpable small intestine or not and abdominal discomfort varying from mild to severe. The objective of this work is to report a case of a 5-year-old female Quarter Horse, weighing 430 kg, with a history of abdominal discomfort two days ago and with intermittent pains, from the municipality of Batatais, Veterinary Hospital of Batatais, addressing the animal clinic, diagnosis and treatment. In the rectal palpation he identified slightly distended loops and palpable small intestine and puncture of the peritoneal fluid through the abdominocentesis showed a reddish coloration. The animal was under observation, but even with all the clinical interventions, the pain picture increased and with that it was submitted to exploratory laparotomy, where the incarceration was diagnosed in the epiplastic foramen. In view of the clinical case, it was concluded that the incarceration of the epiplastic foramen may lead to significant intestinal loops involvement, progressing to destabilization of the general state of the animal, being aggravating factors for the surgical procedure, becoming a case of risk of the patient. The animal in this report was submitted to euthanasia due to the great compromise of the intestinal loops. It is concluded that the diagnosis should be performed as early as possible, increasing the chance of resolution with favorable prognosis.
Who Is Feeling the Heat?: Vulnerabilities and Exposures to Heat Stress--Individual, Social, and Housing Explanations
Authors: Seebaß Katharina
Published: June 2019

Ongoing climate change has led to an increase in extreme temperatures, which influence both the environment and human beings. However, not everyone is affected by heat stress to the same degree. This article analyzes who is affected by subjective heat stress. Individual and social indicators of vulnerability and exposure—mediated by conditions of housing and living environments—are considered simultaneously, from the sociological perspective of social inequality influences. Using local data from an empirical survey in Nuremberg, Germany, the article shows that age, individual health, and social contexts all explain variations in how people experience heat stress. It is further hypothesized and confirmed that heat exposure due to disadvantaged housing conditions or distance from green space increases the levels of subjective heat stress. When looking at differences in levels of subjective heat stress, the consideration of heat exposure due to social vulnerability and socioeconomic reasons offers some explanations.
Hunting for Nature’s Treasures or Learning from Nature?: The Narrative Ambivalence of the Ecotechnological Turn
Authors: van der Hout Sanne , Drenthen Martin
Published: June 2019

Scientists need narrative structures, metaphors, and images to explain and legitimize research practices that are usually described in abstract and technical terms. Yet, sometimes they do not take proper account of the complexity and multilayered character of their narrative self-presentations. This also applies to the narratives of ecotechnology explored in this article: the treasure quest narrative used in the field of metagenomics, and the tutorial narrative proposed by the learning-from-nature movement biomimicry. Researchers from both fields tend to underestimate the general public’s understanding of the inherent ambivalence of the narratives suggested by them; the treasure quest and tutorial narratives build upon larger master narratives that can be found throughout our culture, for instance, in literature, art, and film. We will show how these genres reveal the moral ambivalence of both narratives, using two well-known movies as illustrations: Raiders of the Lost Ark (1981) and Disney’s The Sorcerer’s Apprentice (1940).
The Usefulness of Interactive Governance for Underground Planning
Authors: Nouzari Ehsan , Hartmann Thomas , Spit Tejo
Published: June 2019

The underground provides many spatial planning opportunities as it offers space for structures, but also functions as a resource for energy. To guide developments and use the capabilities the underground provides, the Dutch national government started a policy process for the Structuurvisie Ondergrond (a master plan). Stakeholders are involved in the policy process because of the many interests linked to underground functions. However, past policy processes related to the underground dealt with lack of stakeholder satisfaction. This article explores a quantitative approach by focusing on (a) statistical testing of four criteria of interactive governance and (b) using said criteria to evaluate the satisfaction of stakeholders in a policy process. This article highlights the usefulness of a more quantitative approach and provides new insights into the relation between interactive governance and the procedural satisfaction of stakeholders. It also provides insights that help to improve interactive governance in terms of process management to achieve greater procedural satisfaction.
Research in the Dark
Authors: Schulte-Römer Nona
Published: June 2019

Edensor, Tim. 2017. From Light to Dark: Daylight, Illumination, and Gloom. Minneapolis: University of Minnesota Press.
Bille, Mikkel. 2019. Homely Atmospheres and Lighting Technologies in Denmark: Living with Light. New York: Bloomsbury Academic.
Descriptive Portrait of Teacher Attrition at Tennessee Charter Schools
Authors: Campbell Matthew , Gesualdi Nicholas , Moquin Rachel
Published: June 2019

This study offers an analysis of teacher attrition patterns at charter schools in Nashville and Memphis, Tennessee. Using survey data from 121 teachers, the study reports teacher opinion regarding four common causes of teacher attrition, examines the role of demography and school organization on future attrition plans, and offers various regression models in an attempt to predict future plans for the teachers within the sample. Overall, teachers reported lukewarm feelings regarding common causes of teacher attrition, and no background characteristic or school organizational structure held significance for future plans.
Solo hay que ponerse crema para el sol: a propósito de un caso de lupus eritematoso sistémico
Authors: Díaz de Neira Hernando M. , García Murillo L. , Forti Buratti M. A.
Published: June 2019

Se presenta el caso de una chica de 14 años diagnosticada de lupus eritematoso sistémico recientemente. Se describe la intervención a nivel individual y familiar en el acompañamiento durante el duelo producido por el diagnóstico, ilustrando con fragmentos de sesiones las diferentes fases de duelo por las que atraviesan ella y su familia. Se pone de manifiesto la importancia de validar las emociones y dejar espacio a la expresión de las mismas, especialmente las negativas. Aunque el caso ilustra un caso de lupus eritematoso sistémico, lo descrito se puede generalizar para cualquier enfermedad crónica diagnosticada en la infancia o adolescencia.
The Satellite Account of Expenditures on Environmental Protection: Methodological Aspects of Its Introduction in Ukraine
Authors: Kobylynska Т. V. , Momotiuk L. Ye. , Motuzka О. М.
Published: June 2019

The article is devoted to methodological aspects addressed in building up the framework for the satellite account of the expenditure on environmental protection in Ukraine. It is argued that any study of the environment need computations and analyses of quantitative indicators based on the statistics data. Problems of statistical accounting are, therefore, the central ones in investigating the expenditure on environmental protection. One of the most urgent tasks is to ensure comparability of data, to enable comparisons of data at all the levels in order to find output key tendencies and patterns in the expenditure on environmental protection, comparisons of figures relating to environmental protection and macroeconomic situation. 
The article contains an analysis of the phases of creating the European standard of the system for environmental-economic accounting on the whole and the environmental protection expenditures account in particular. The sources of data for creating the satellite account for the expenditure on environmental protection in Ukraine, and the indicators included in the EU questionnaire designed to collect data on national expenditures on environmental protection are highlighted.
It is demonstrated that data from many sources are used to build the satellite account for the expenditure on environmental protection. It is mentioned that by now Ukraine has not introduced ad hoc surveys of households on the expenditures on environmental protection.
Results of the study show that the main sources of data for computations of the expenditures on environmental protection in Ukraine can be the official statistical observation by type of expenditure, collected by form 1 – environmental expenditure (annual) “Expenditures on environmental protection and environmental payments”, where the expenditure are recorded according to the Classification of Environmental Protection Activities.
The sources of secondary information, i. e. the data from regular official statistical observations and administrative data that are collected with other purposes and reflect selected aspects of expenditure on EP, are recommended for use when developing the methodology.
Estimation the Labor Force Replacement Demand in Ukraine, Caused by Its Outflow Due to the Age and Labor Migration
Authors: Sarioglo V. G. , Ogay М. Yu.
Published: June 2019

The article describes an effective approach to the anticipation of the labor force demand caused by the need to it replace (the replacement demand). The emphasis is made on estimation the outflow of workforce due to the retirement and labor migration. 
The importance of medium-term forecasting (for 10 years) of the labor force demand, caused by the need to replace the workers flowing out of the labor market as a whole and separate occupational or qualification groups in particular is justified in the Ukraine’s context. The data sources and methodological approaches to the anticipation of the replacement demand are highlighted. It is shown that the main source of data for the labor force replacement demand anticipation in Ukraine, like in many other countries, is the state labor force the sample survey. A serious problem for Ukraine is accounting of labor migration effects for the replacement demand, which is assessed by conducting ad hoc surveys. The main methods used in anticipation of the replacement demand are method of trend extrapolation, methods of pseudo-cohorts, and stock-flow modeling. These methods enable for assessing and accounting of not only the processes of outflow of the labor force due to the age, but also transitory processes reflected, inter alia, in changes of qualifications and/or professions by young people at the beginning of their carrier.
A medium-term anticipation of the labor force demand in Ukraine, caused by outflow of the labor force due to the age and labor migration, is performed. It is shown that the replacement demand caused by outflow of the workers due to the age, accounts for a most significant part of the overall demand for workforce, making up in medium-term perspective nearly 13% of the total employment in 2017. The level of the demand has strong variations across occupational and qualification groups: in the occupational group “the simplest occupations”, the average annual demand caused by the outflow due to the age will be nearly 3.4% of the total employment.
It is shown that the replacement demand in Ukraine by occupational group may substantially increase due to labor migration. Thus, the high replacement demand for workers in the simplest occupations is enhanced by the external labor migration of such workers, which share is nearly 42% of the total labor migrants.
Statistical Foundation of Historical Facts
Authors: Gerasymenko S. S. , Gerasymenko V. S.
Published: June 2019

In the article the reasonability of using statistics in modeling and prognostication of historical events is substantiated. The usage of statistics in investigation of history is caused by the fact that the development of the sociality is determined by the interaction of different historical events, each of them – from one side – is connected with definite events which took place in the past, and from the other side – forms the events of the future. Thus, history as the object of investigation is the whole set of interconnected elements – events, the behaviour of which can be described with the help of appropriate statistical models.
In particular, the behaviour of people is determined – first of all – by the biological factors among which the need for food is on the first place. Hypothesis, that the shortage of food is the motive power of historical events, was checked according to the information about the range of events which took place in Ukraine in XVI – XVII centuries. Recurrent 600-year fluctuation of solar activity caused the global negative changes of the climate in Europe and in Ukraine in 1550 – 1650. As a result – regular crop failure and famine, the influence of which for 26,5% of the territory of modern Ukraine (which at that time belonged to Rzecz Pospolita), was increased by the regular forays of Turks and Crimean Tatars.
The tendency correlation coefficient of 10 main historical events of those times with the “starvation years”, the origin of which was caused by two mentioned above factors, exceeded 85%, and it is quite enough level for not to decline the hypothesis about the interconnection which is being investigated, taking into account the particularities of information which was used.
The stated supposition and the received results allow to make the conclusions that there were and there always are the objective factors, which cause the historical events, the level of which can be determined and to measure the extent of their influence on the historical events.
Statistical Grounding of New National Priorities for the Land Using in the Agrarian Sector
Authors: Shchuryk M. V. , Hudzyk І. V.
Published: June 2019

Land resources of the agrarian sector are the most important сomponent of the national wealth of Ukraine. However, the efficiency of their use does not meet the present-day requirements, as it is aimed at the permanent increase in the gross output of agricultural products without taking into account the need for improvement and protection of soils, observing the ontology laws and ecology preservation. Land and agrarian reforms implemented through sharing and privatization of land plots have caused the formation of two largest groups of users and owners of agricultural lands: agroholdings and households. However, small and medium agrarian entities have not been properly developed, as it is done in many EU countries.

The transformation of land relations in the domestic agrarian sector was directed to searching an honest landlord which had to be households. However, as follows from the study, true owners of land plots could not be found, as the reforms were implemented with significant violations and abuses. As a result, in many cases owners of land plots became individuals who were not directly related to agricultural lands. Unclaimed land shares and increased numbers of plots left by small owners indicate the failure of the land reform. 

The owners of agroholdings exploiting their lands to obtain extra profits failed to use the leased lands in an efficient manner, mainly because the profitability of land was achieved without taking into account the need for preserving the soils fertility; the need to respect the laws of ecology and optology preservation is also ignored.

The article substantiates the need of introducing new national priorities for the use of agricultural lands, where the formation of small and medium-sized agricultural enterprises should become the key measures. The need for inventory of land plots of the agroindustrial complex by land plot, land owner and land user is demonstrated, which will serve as a roadmap for developing the program of land use in the context of globalization and integration processes.  Efficiency enhancement of the existing agrarian entities and creating new ones by analogy with the EU countries should become a new priority of the land use policy.

The authors propose to engage the capacities of domestic R&D to setting the priorities of land use in the newly created united territorial communities.
Analysis of Information Support of Knowledge Management in Ukraine
Authors: Oliinyk O. O.
Published: June 2019

The article defines the place and components of IT solutions in the knowledge management system. The author substantiates that the use of modern IT solutions in the knowledge management system is an essential component of creation, search, transfer, exchange, development and effective use of knowledge. A large number of different technologies are used to integrate into a single complex of knowledge management system, including traditional automation systems and information retrieval systems, e-mail, corporate networks and Internet services, databases and data warehouses, electronic document management systems, specialized data processing programs, expert systems and databases knowledge In this case, a computer remains as a main tool of information management knowledge management in Ukraine. The scholar analysed the dynamics of the major indicators of computer devices’ use of by enterprises. The paper determined that not all enterprises in Ukraine use computers in their business activities. The proportion of enterprises, which used computers in 2017, amounted for 95.4%, which is by 0.2% more in comparison with 2015. The best situation in this aspect is in such types of economic activities as professional, scientific and technical activities; information and telecommunications; water supply; sewage, waste management. However, on average only every third employee in Ukraine used a computer to perform his/her professional duties. The author examined the main Internet-based jobs, where traditional activities are the most popular ones, namely: sending or receiving various e-mails, receiving information about goods and services. At the same time, videoconferencing is less popular, which is a negative factor in creating effective communication in the transmission, dissemination and exchange of knowledge. The paper explored the degree of using the possibilities of a corporate website for personnel training. The author determined that only every tenth enterprise in Ukraine uses its own website for the professional development of the employees. The scholar substantiated the features of social media, which promote the efficiency of their use as a tool for knowledge management. Exchanging views, opinions or knowledge within the enterprise and engaging customers in the development or innovation of goods and services remain the least popular objectives of social media work.
The tidal effect on the climatic characteristics of the Kara Sea in the ice-free period
Authors: Kagan B. A. , Sofina E. V. , Timofeev A. A.
Published: June 2019

Using a high-resolution version of the QUODDY-4 three-dimensional finite-element hydrostatic model, we have carried out two series of numerical experiments. The first estimates tidal changes characterizing the role of tides in the formation of climatic characteristics of the Kara Sea in the ice-free period (the magnitude and directions of velocity of permanent surface currents, temperature, and salinity at the pycnocline base and level of the free sea surface). The second series checks the adequacy of the indirect description of tidal changes in terms of tide-induced baroclinic tidal-energy dissipation and diapycnal diffusion when compared to the explicit method and obtains a quantitative measure that can be used for their comparison. The modeling results indicate, first, that the tidal changes are a significant, if not key, factor; second, that the indirect description of tidal changes is adequate when compared to the explicit method; third, that it is unjustified to disregard these changes (this is common in predicting and computing the climates of marine systems); and, finally, that the correlation averaged over the sea surface area can be taken as a quantitative measure of the similarity of the fields of climatic characteristics obtained for the total (wind + thermohaline + tidal) forcing, on the one hand, and the combined (wind + thermohaline) forcing coupled with the indirect method for the description of tidal changes, on the other.
Model of the windward slope formation of the eolian relief form
Authors: Malinovskaya E. A.
Published: June 2019

The model for establishing the windward slope upon exposure to the air flow is based on the analysis of the state of the layer composed of sandy incoherent particles. It is assumed that the wind removal of individual particles of this layer leads to a change in its length due to rolling and immobility of larger particles. Accounting for precipitating saltating particles gives an idea of the reasons for the alternation of layers of large particles with layers of smaller ones involved in wind-sand transport. Assuming a linear dependence of the dynamic velocity on the height of the location on the windward slope, the forms of the windward slope, which are close to the observed ones, are obtained. An algorithm for determining the linear coefficient of change of dynamic velocity is proposed. The calculation of the relative change at different levels of the windward slope of the values of the roughness parameter and the scale of the laminar layer made it possible to estimate the coefficient of surface resistance.
Regularities in variations of the pume volcanics composition in the Southern Atlantic and at the African plate
Authors: Chernysheva E. A. , Eroshenko D. V.
Published: June 2019

The action of the African Superplume provided input and accumulation of the volatile, alkaline and some others elements at the base of continental lithosphere. Transformation and interaction of these components with mantle peridotites took place under the African continental plate of the great thickness. Generation of low silica and rich in CO2 melts occurs at the great depth: this is the family of kimberlites, melilitites and carbonatites. At the shallower levels of the lithospheric plate the melts of basalts originated; they are more rich in SiO2 and poor in volatiles. The origin of deep generated volcanics was controlled by the pressure of CO2 in the fluids. The melting of basalts is connected mainly with tectonic position.
Networks with Extremal Closeness
Authors: Rupnik Poklukar Darja , Žerovnik Janez
Published: June 2019

Closeness is a measure of centrality, an important feature of communication and social networks. Extremal networks among all graphs and among several subclasses of graphs including trees and cacti are given. In addition, maximal graphs among cacti with fixed number of cycles and among cacti with given number of cut edges are provided.
Spatial modeling of shot conversion in soccer to single out goalscoring ability
Authors: Deb Soudeep , Dey Debangan
Published: June 2019

Goals are results of pin-point shots and it is a pivotal decision in soccer when, how and where to shoot. The main contribution of this study is two-fold. First, we show that there exists high spatial correlation in the data of shots across games. Then, we introduce a spatial process in the error structure to model the probability of conversion from a shot depending on positional and situational covariates. The model is developed using a full Bayesian framework. Next, based on the proposed model, we define two new measures that can appropriately quantify the impact of an individual in soccer, by evaluating the positioning sense and shooting ability. As a practical application, the method is implemented on Major League Soccer data from 2016/17 season.
What Comes After Immuno-Oncology Therapy for Kidney Cancer?
Authors: Zahoor Haris , Duddalwar Vinay , D’Souza Anishka , Merseburger Axel S. , Quinn David I.
Published: June 2019

The treatment landscape of advanced renal cell carcinoma (RCC) is rapidly evolving. Immune checkpoint inhibitors (ICI) have now become the preferred first line treatment with the approval of nivolumab and ipilimumab combination in intermediate to poor risk patients. Combination/s of ICI with vascular endothelial growth factor (VEGF) inhibitors will also be approved in future. The optimal treatment of patients who progress on ICI-based therapies is not well defined as of yet. In this review, we discuss the data regarding various treatment options available in this space, their limitations, and also provide our opinion regarding treatment selection.
Sunitinib Dose Escalation in Metastatic Renal Cell Carcinoma
Authors: Bruchbacher Andreas , Nachbargauer Sebastian , Fajkovic Harun , Schmidinger Manuela
Published: June 2019

Background and objective:

Sunitinib has been a standard treatment for patients with metastatic renal cell carcinoma (mRCC) since 2006. However, almost all patients will eventually progress. Besides well described mechanisms of primary or secondary resistance, insufficient drug exposure may lead to disease progression. The aim of this study was to identify patients in whom sunitinib dose escalation was performed and to analyse safety and efficacy of this strategy in clinical practice.

Methods:

A single-centre retrospective study on dose escalation in mRCC patients who were treated with sunitinib at the Medical University of Vienna between January 2011 and May 2016. Dose escalation was studied in patients who had either progressed (cohort 1: PDescal) or had stable disease with minor progression (cohort 2: SDescal). The primary endpoints were response rate before and after dose escalation, global progression free survival and overall survival. Secondary endpoints were treatment duration before and after dose escalation and toxicity.

Results:

Dose escalation up to 75 mg was offered in 21 out of 265 patients. Response rates before and after dose escalation were 42,8% and 23.8%, respectively. The median global PFS and OS were 15.60 and 32.95 months, respectively. The median treatment duration before and after dose escalation was 6.1 months (1.3–29.3 months) and 6.6 months (2.5–16.6 months). No new toxicities emerged under escalated dose and no grade 4 adverse events occurred.

Conclusion:

Sunitinib dose escalation may be a strategy in patients with few toxicities at the time point of progression.
A corpus-based analysis of scrambling in Japanese in terms of anaphoric and cataphoric co-referencing
Authors: Imamura Satoshi
Published: June 2019

In Japanese, word order changes do not affect the grammatical relations between constituents, allowing both SOV and OSV word order. Although it has been assumed that the choice of word order is determined by information structure, it is unclear how OSV is related to information structure. In order to shed light on this issue, this article investigates the usage of OSV under the framework of the Givónian approach, using a corpus-based method. First, the study demonstrates that the object is informationally older than the subject in OSV while there is a reverse relationship between the object and the subject in SOV. Second, the study reveals that the referents of the subject both in SOV and OSV tend to be carried over to the following sentences. Consequently, I conclude that OSV correlates with the ‘topic shift’ from the referent of the scrambled object to that of the subject. Therefore, OACCSV is selected when the writer intends to start a new discourse and continues writing about the referent of the subject after OACCSV appears.
Wait-time in Material and Classroom Context Modes
Authors: Atar Cihat
Published: June 2019

This study aims to investigate wait-time, more specifically student reaction wait-time, in high school English as a foreign language classrooms with specific regard to two classroom micro-context modes (the classroom context mode and material mode). The data was collected via audio-recordings of classroom interaction in its natural context. The audio-recordings were analyzed using the principles of Conversation Analysis. The analysis of the data demonstrated that the effectiveness of student reaction wait-time is highly related to the current pedagogical goal; if the purpose is to increase learners’ involvement in classroom discourse or if it requires analytical thinking, an extended wait-time of three to five seconds is likely to enhance the learning opportunity. However, as a social process, opportunities for learning are likely to be missed if the purpose is to monitor understanding or display answers which are explicitly given in the material that is being used. In this sense, this study has implications for studies on wait-time, foreign language classroom interaction, teachers’ interactional competence, and foreign language learning contexts in general.
Life Skills as a Predictor of Psychological Well-Being of Pre-Service Pre-School Teachers in Turkey
Authors: KASAPOĞLU Koray , DİDİN Melek
Published: June 2019

This study aims to investigate the relationship between pre-service pre-school teachers’ life skills and psychological well-being and to determine whether or not various variables related to pre-service pre-school teachers (gender, age, grade level, type of instruction, cumulated grade point average, status of taking course about life skills) and their life skills significantly predict their psychological well-being. In this quantitative study with correlational design, data were gathered from 391 pre-service pre-school teachers studying at a state university, with 5-point Likert-type Life Skills Scale developed by Bolat and Balaman (2017); 7-point Likerttype Psychological Well-being Scale developed by Diener, Wirtz, Tov, Kim-Prieto, Choi, Oishi and Biswas-Diener (2010) and adapted into Turkish by Telef (2013). Data were analyzed through descriptive statistics, canonical correlation and hierarchical regression. It is concluded that pre-service pre-school teachers’ psychological well-being levels are relatively high and that the life skill they developed most is communication and interpersonal relationships. Canonical correlation results indicate that there is a medium-level relation between life skills and psychological well-being and that psychological well-being is significantly predicted by gender, age, and the following life skills: “empathy and self-awareness”, “decision-making and problemsolving”, “creative and critical thinking”. Anahtar Kelimeler Pre-school curriculum, Pre-service pre-school teacher, Psychological well-being, Life skills
Analyzing the Digital Addiction of University Students through Diverse Variables: Example of Vocational School
Authors: Bağcı Hakkı
Published: June 2019

Today, when information technologies are evolving rapidly, digital platforms such as computers, the internet, social media and smartphones have become essential parts of our lives. These digital platforms are intensely used by people with a variety of ages. Students mostly use digital platforms to communicate, navigate on social media and playing online and offline games. The digital platforms, which are used for those diverse aims, influence our lives and especially create addiction for students. In this context, the students of vocational schools may be negatively influenced by the intense usage of digital platforms. This study in this regard aims to examine the digital addiction levels of vocational school students and the degree of this addiction based on their genders, departments, school years and levels of income. A survey method was used in this study. 318 foundation degree students from different departments at Sakarya University and Sakarya University of Applied Sciences participated in this study. In order to collect data, a demographics form and the “Digital Addiction Scale”, developed by Kesici and Tunc (2018), were used. The results of the study suggest that the participants have a medium-level addiction. While the students have a mid-level addiction at overuse, non-restraint, emotion situation and sticking sub-dimensions, they have a low-level addiction at inhibiting the flow of life. The digital addiction of vocational school students does not differ according to their school years, genders and income levels of their families but differ by their departments. It is advised that for today's students to use digital courses in an accurate and effective way, new educational methods should be used, and students, parents, teachers and administrators need to be trained to learn the negative psychological and physical effects caused by digital addictions such as the internet, smartphones, computers and social media addictions.
The Effects of Authentic Video Materials on Foreign Language Listening Skill Development and Foreign Language Listening Anxiety at Different Levels of English Proficiency
Authors: POLAT Mustafa , ERİŞTİ Bahadır
Published: June 2019

The study aims to find out the effects of authentic video materials on foreign language listening skill and foreign language listening anxiety of students studying at different levels of English proficiency. The experimental practices of the research designed as pretest-posttest true experimental design with control group have been conducted on two experimental and two control groups. While the independent variables of the study are authentic videos and English proficiency levels, the dependent variables are English listening academic achievement levels and English listening anxiety levels of the students. The participants of the research consisted of 100 randomly selected students, who have A1 and B1 levels of English proficiency, studying English preparatory program at the school of foreign languages at a state university. Data collection tools utilized in the study are Key English Test (KET) and Foreign Language Listening Anxiety Scale (FOLLAS). The statistical analysis of the research data was carried out by using descriptive statistics, independent samples t-tests, effect size tests and correlation analysis. Findings show that authentic video materials reflecting the real language and communication samples, have highly effective results on the development of English listening skills and lowering the foreign language listening anxiety of students who have A1 and B1 levels of English proficiency. On the other hand, as students' language proficiency improves, the impact of authentic videos increases. Finally, when it is compared to control groups, values obtained by the analysis reveal that there is a much stronger correlation among the development of listening, reading, writing and speaking language skills of experimental group students whose English listening skills have improved by using authentic videos.
Congenital Hypotrichosis Simplex: A Case Report
Authors: Kibtiar Maria , Akther Romana , Islam Mohammed Mahbubul , Rahman Shahana A
Published: June 2019

Congenital hypotrichosis simplex of scalp is a rare disorder which only affect the scalp hair. Rest of the hair bearing areas are spared. In this disorder the scalp hair are absent or sparse. We describe a 5 month old boy presented with no growth of scalp hair since birth in this case report. After taking detailed history, a thorough physical examination was done. Other causes of alopecia were ruled out and finally the child was diagnosed as a case of Congenital Hypotrichosis Simplex (CHS).

Bangladesh J Child Health 2019; VOL 43 (1) :59-61
Abstract from Current Literature Vol.43(1)
Authors: Editor The
Published: June 2019

Abstract not available

Bangladesh J Child Health 2019; VOL 43 (1) :69-70
In vitro regeneration and molecular characterization of some varieties of Lycopersicon esculentum Mill. in Bangladesh
Authors: Billah M , Banu TA , Islam M , Banu NA , Khan S , Akter S , Habib A
Published: June 2019

An efficient regeneration protocol was established for two varieties (BARI tomato-9 and BARI tomato-15) of tomato (Lycopersicon esculentum Mill.) using three explants namely cotyledonary node, cotyledonary leaf and hypocotyls. Among the three explants, maximum number of shoots was produced from cotyledonary leaf explants of BARI tomato-15 on MS with 2.0 mg/l BAP and 0.5 mg/l IAA. In this combination of BAP and IAA 86%, on an average, cotyledonary leaf explants showed regeneration response 14.12 shoots/explants. Explants from hypocotyl showed best results in MS medium with 2.0 mg/l BAP and 0.2 mg/l IAA in both the varieties. In case of cotyledonary node, BARI tomato-15 showed 6.0 shoot/explant on MS with 2.0 mg/l BAP and 1.0 mg/l IAA. Molecular characterization of total ten varieties of tomato in Bangladesh was done by using six arbitrary oligonucleotide RAPD primers. A total of 140 bands were produced where the highest genetic distance (0.6769) was found between BARI tomato-3 and Mintoo tomato and lowest distance (0.1035) was observed between BARI tomato-7 and BARI tomato-8. This result will be useful for designing future breeding programs.

Bangladesh J. Sci. Ind. Res.54(2), 117-124, 2019
Design and development of solar dryer for food preservation
Authors: Tabassum S , Bashar MS , Islam MS , Sharmin A , Debnath SC , Parveen S , Khanom SAA
Published: June 2019

Solar thermal energy is an alternative source of energy which can be used for drying vegetables, fishes, fruits or other kinds of material, such as wood. In Bangladesh, there exist significant post-harvest losses of agricultural products due to lack of the use of proper preservation system. Drying by using solar thermal energy can be an effective solution for this loss. As Bangladesh is situated in latitude 23°43’N and longitude 90°26’E, this is very much suitable to use solar thermal energy. To reduce the limitations of the natural sun drying e.g. exposure of the foodstuff to rain and dust; uncontrolled drying; exposure to direct sunlight; infestation by insects etc., two types of solar dryer (low cost solar dryer for small production and solar dryer for large production) were developed. The design was based on the geographical location of Dhaka, Bangladesh. The experiments were conducted to dry vegetables and fishes. The obtained results revealed that the temperatures inside the dryer were much higher than the ambient temperature. The rapid rate of drying proves its ability to dry food to keep in safe moisture level in a hygienic environment. Microbiological and nutritional values ensure a superior quality of the dried product also.

Bangladesh J. Sci. Ind. Res.54(2), 155-160, 2019