bluuebunny/crossref_metadata_2025 huggingface dataset:
Passive convective ventilation in a double air-porous layer with internal heat generation depending on solid fraction
Authors:   Perm State University, Kolchanova Ekaterina A. , Kolchanov Nikolay V. ,   Perm State University
Published: May 2023

The convective stability of a two-layered system consisting of a heat-generating porous region underlying an air region has been numerically studied. The linear dependence of the heat release on the solid volume fraction is taken into account in the porous region. The equal constant temperature values are fixed on the external impermeable boundaries of the system. The critical internal Rayleigh-Darcy number at which the convection is induced in the system in the form of two-dimensional roll patterns with a given wave number has been determined. The convective flow is possible due to the formation of unstable density stratification in the presence of internal heat release. Two types of stationary convection, namely, the local and the large-scale convection, have been studied. The local flow arises in the air sublayer and scarcely penetrates into the porous sublayer. The large-scale convection covers both sublayers. The change in the convective regime occurs with the growth of one or another parameter of the system and indicates the variation of the instability type. It is accompanied by an abrupt (by times and tens of times) change in the critical wave number of roll patterns. Numerical calculations show a decrease in the onset value for both types of convection with increasing solid volume fraction ϕ in the porous sublayer and increasing relative thickness d of the air sublayer. The growth of the Darcy number (the dimensionless per-meability of the porous sublayer) also causes destabilization of the air motionless state at the given ϕ and d. The variation of the convection regime from a large-scale flow to a local one occurs with increasing relative thickness of the air sublayer, whereas an opposite transition from the local to the large-scale convection regime is observed with increasing Darcy number.
Investigating the Dimensionality of Young’s Internet Addiction Test for University Students Using Mokken Scale Analysis
Authors: AVCU Akif
Published: May 2023

The Internet Addiction Test has been used extensively by researchers to collect data from university students, However, empirical studies on the psychometric properties of this test have revealed conflicting results on the factor structure. Although the structure of Internet addiction is generally accepted as unidimensional, these contradictory results require further evidence for the unidimensional nature of the construct. Considering the existing problems regarding the factor structure of the Internet Addiction construct, the aim of this study was set as evaluating the unidimensionality of the Short Internet Addiction Test for University Students by using Mokken Scaling Analysis. The Internet Addiction Test short form was administered to 636 university students studying in Turkey in the 2020-21 academic year via an online data collection platform. The ages of the participants ranged from 20 to 65. The results revealed that the items of the Internet Addiction Test Short Form were scalable and homogeneous enough to form a separate scale. On the other hand, the results showed that the Internet Addiction Test Short Form did not have the Invariant Item Ranking feature. In addition, using the backward selection method, a seven-item form of the Internet Addiction Test Short Form, which has Invariant Item Ordering feature, is proposed. These results showed that the structure of internet addiction can be accepted as one-dimensional for Turkish university students. It is recommended to examine whether the results obtained in future studies can be generalized to different universes.

Keywords: Mokken scaling analysis, internet addiction, dimensionality, university students.
Protocol for use with NEBNext Poly(A) mRNA Magnetic Isolation Module (NEB #E7490) and NEBNext Ultra II Directional RNA Library Prep Kit for Illumina (E7760, E7765) v2
Authors: England Biolabs New
Published: May 2023

The NEBNext Ultra II Directional RNA Library Prep Kit for Illumina contains the enzymes and buffers required to convert a broad range of input amounts of RNA into high quality directional (strand-specific) libraries for next-generation sequencing on the Illumina platform. The fast, user-friendly workflow has minimal hands-on time and is compatible with poly(A) mRNA enrichment and rRNA depletion methods.
Workflow for SNP genotyping using the Hi-Plex method v1
Authors: Besnard Anne-Laure
Published: May 2023

Many research questions in ecology and evolution require balancing sampling strategies between their spatial (how many populations? on which geographical, environmental gradients?), temporal (diachronic approaches), and genomic (how many and which loci?) dimensions. High-throughput molecular biology protocols often offer very good genomic coverage, but this is often only achievable at the expense of other sampling dimensions. This has led to the development of targeted genotyping strategies for SNP locus sets, in addition to whole or reduced genome sequencing strategies. We here present an adaptation of a protocol developed by the University of Melbourne for genotyping rare variants in human oncology to non-model species for use in ecology and evolution. Hi-Plex is an amplicon sequencing technique (sensu Meek & Larson 2019) in which all loci are co-amplified in a multiplex reaction before Illumina or Ion-Torrent sequencing (we used Illumina). Intermediate steps include dual indexing of individual samples used for demultiplexing.
Staining the Human Vagus Nerve with Osmium Tetroxide and Micro CT imaging v2
Authors: R. Upadhye Aniruddha
Published: May 2023

In this protocol, we describe our steps to stain nerve fibers with Osmium Tetroxide for further visualization wtih microCT, 3D MUSE (Microscopy with Ultraviolet Surface Excitation), and electron microscopy.
THE PERSONNEL POTENTIAL TO FOSTER SOCIOECONOMIC DEVELOPMENT IN UKRAINE UNDER MODERN CONDITIONS
Authors:   National Institute for Strategic Studies, Kyiv, Ukraine, Lisogor L. , Rudenko N. ,   Taras Shevchenko national University of Kyiv
Published: May 2023

The economic content and specifics of the “personnel potential” concept at the individual, micro, and macro levels have been investigated. The study explored the component structure of personnel potential characterized by the presence of demographic, educational and knowledge, qualification, and motivational components. The paper examines factors affecting the formation, use, and development of personnel potential. The main stages of evolutionary changes in personnel potential have been singled out. The problems and risks of deteriorating the quantitative and qualitative characteristics of the personnel potential associated with the impact of crisis phenomena in the demographic, social, and economic spheres have been identified. It was noted that in the conditions of the war, there was a gradual narrowing of the demographic base for the reproduction of personnel potential due to the migration outflow of a significant part of the working-age population; reduction of the number of jobs. It has been proven that to increase the efficiency of the use of personnel potential at the micro, meso, and macro levels, it is advisable to improve the practice of forming the personnel reserve. The need was shown to stimulate employers improve employees’ skills and qualifications by obtaining assistance from the state employment service on the organization of professional training. The main directions for improving the quality of personnel potential at the regional and national levels are defined as an elaboration of the strategies for the development of personnel potential at the national and regional levels, preparation of the training programs, and upgrading of qualification of management personnel of local authorities. The directions are substantiated to minimize the risks and overcome the negative consequences of the deterioration of the quality of personnel potential to ensure the stabilization and acceleration of the recovery of the country’s economy based on innovation.
COMPANY PROMOTION STRATEGY IN INTERNATIONAL B2B MARKETS
Authors:   Taras Shevchenko national University of Kyiv, Prygara O. , Skoryna Yu. ,   service support for export sales of PJSC “MHP”, Kyiv, Ukraine
Published: May 2023

The research focuses on the company’s promotion strategy in international B2B markets, revealing different approaches to the promotion concept and strategy. The promotion strategy is viewed as a way of determining the company’s long-term goals for building a system of marketing communications between the company and a consumer regarding the dissemination of information about products using communication tools (advertising, PR, personal selling, direct marketing, sales promotion) aimed to form the demand for goods. The research studies the causes influencing the international communication process: uncontrollable and rapidly changeable factors of the market context of domestic and foreign markets, aspects of sociocultural, linguistic, economic, legislative, and competitive differences in the market. These factors actualize the necessity of strategic analysis of international markets, detailed analysis of the socio-cultural environment, and thorough analysis of secondary and primary marketing information regarding differences in the customers’ market behavior in the global market. The study describes the formation of a company’s promotion strategy for international markets. It includes the following stages: strategic analysis of foreign markets’ attractiveness, analysis of the cultural environment of global markets, the foreign market selection process for further market activity, research of customers’ motivations in the chosen market, determination of directions for the promotion strategy formation and means for its implementation and control. A comparative analysis of the use of promotional tools in B2B and B2C markets is provided. It is determined that the most effective promotion tools in the B2B market are personal sales, exhibitions, event marketing, and presentations.
Correction of age-related changes of the face skin using radiofrequency micro needling. Brief literature review
Authors: Agapova Marina A. , Sharova Alisa А.
Published: May 2023

The problem of choosing a method for skin rejuvenation remains relevant despite a wide selection of conservative and surgical methods for eliminating age-related changes. In recent years, treatment methods for voluminous and traumatic ones have been striving for minimally invasive, quickly feasible with an optimal result that should meet both the needs of patients and doctors. For this reason, injection and hardware methods of rejuvenation began to come to the fore, especially when correcting changes on the face. Cosmetic devices based on radiofrequency can compete in efficiency with laser technology, having their own specific advantages.
The aim of the work was to evaluate the available literature sources related to the use of radiofrequency in dermatology and dermatocosmetology, especially for leveling age-related changes in the skin of the face.
The available literature sources from Russian and foreign databases (Elibrary, PubMed, Google Academia) were analyzed on the use of radiofrequency and radiofrequency micro needling in dermatocosmetology for facial skin rejuvenation.
The analysis showed the widespread use of radio frequency in dermatocosmetology, its high efficiency and safety, however, there are very few full-fledged studies devoted to radio frequency microneedling.
In our opinion, radiofrequency microneedling is a significant step forward compared to traditional radiofrequency devices, especially for facial skin rejuvenation by increasing the safety and effectiveness of the procedure. The use of radiofrequency microneedling can be effective for correcting age-related skin changes, especially in the face area, both as monotherapy and in combination with other methods of rejuvenation.
Reduction of glycemic risks in patients with diabetes mellitus and chronic periodontitis after physiotherapy
Authors: Chkheidze Tinatin , Zhilokov Zaur G. , Tkachenko Albina S. , Kulikova Natalya G.
Published: May 2023

BACKGROUND: The article is devoted to the actual task of reducing inflammatory complications after dental manipulations in patients with diabetes mellitus. It is noted that worldwide there is a steady trend of increasing the incidence of diabetes mellitus and predicting an increase in the number of patients to 250 million people by 2025. The prevalence, severity of dental complications and inflammatory diseases of periodontal tissues in patients with diabetes is extremely high, which determines the relevance and scientific and practical significance of the study.
AIM: to evaluate the score, index dental indicators, cytokine plasma indicators before/after the use of physiotherapy methods in complex dental treatment.
MATERIAL AND METHODS: The study included 121 patients (58 men and 63 women) with diabetes mellitus with an underlying disease duration of up to 5 years who were diagnosed with diabetes periodontal-periodontal inflammatory diseases. Starting and ending points: point, index dental indicators, glycemic profile and immunological cytokine plasma indicators before/after the application of physiotherapy methods before/after the application of physiotherapy methods in complex dental treatment, including a transcanal method of drug electrophoresis with a copper-calcium preparation and laser exposure to NILI (low-intensity laser radiation; l=810 nm). Analysis of statistical data was carried out in Microsoft Office Excel (2017) programs. The differences were considered significant at р 0.05.
RESULTS: It has been established that the use of complex physiotherapy in patients with diabetes reduces glycemic risks and increases antioxidant reserves.
CONCLUSION: The use of complex physiotherapy in patients with type 2 diabetes mellitus reduces the risks of inflammatory complications in periodontal-periodontal tissues, which is confirmed by clinical efficacy in relation to cellular immunity and hygiene index.
Genetic factors of early termination of pregnancy
Authors: Tsechoeva Leila Sh. , Dementyeva Elena I. , Leonova Margarita D. , Poloskov Anton I. , Gavrichkova Yuliya V. , Bardinova Mariya V. , Tapil'skaya Natalya I. , Slizhov Pavel А. , Glushakov Ruslan I.
Published: May 2023

Pregnancy loss and premature delivery are combined by the definition Premature Termination of Pregnancy, while these conditions affect up to 5% of women of reproductive age. In some cases, genetic components are both etiologic and pathogenetic factors of premature birth, however, This challenge is further complicated by the fact that extensive population-based genetic studies and subsequent validation of the data are required, especially in multi-ethnic populations.
Genome-wide studies will demonstrate polymorphic variants of hundreds of genes that are candidates for being associated with termination of pregnancy, including those regulating embryo implantation, pregnancy support, and immune system response. The review provides information about the genes and genetic polymorphisms that are involved in the regulation of the female reproductive system and associated with premature birth. A special role in the genetic mechanisms of miscarriage and/or preterm birth belongs to steroid hormone receptors, enzymes of the arachidonic acid metabolism, pro- and anti-inflammatory cytokines. However, the infectious factor takes the first place as a leading one, forming cause-and-effect relationships in the chain of pathogenetic links or giving modality to other factors. Most often, it is genetic polymorphisms associated with an over-activity of the immune system that underlie premature termination of pregnancy.
Subsequent Investigation of the human genome, epigenome, and transcriptome helps to identify molecular mechanisms linked with preterm delivery and premature newborn clinical appearance in early and late neonatal life and even predict developmental outcomes. These data could be used to develop targeted interventions aimed at selecting the most effective individual treatment and rehabilitation plan. The data obtained in future studies could be used to develop for preconception care, targeted therapy and the most effective individual treatment plan.
Keywords: genetic polymorphism; miscarriage; over-active immune responses; premature birth; premature termination of pregnancy; transcriptome.
Aortic dissection: computed tomography characterization of the true and false lumen in acute and chronic stages
Authors: Sadykova Gulnaz K. , Zheleznyak Igor S. , Amosov Victor I. , Ryazanov Vladimir V. , Bagnenko Sergey S. , Ipatov Victor V. , Latysheva Anastasiya Ya.
Published: May 2023

Aortic dissection is a longitudinal rupture of the aorta associated with the destruction of the middle layer of the aortic wall, the separation of intima and adventitia and the formation of two lumens, which is an urgent condition requiring emergency surgical care. The presented illustrated literature review is devoted to the differentiation of true and false lumens in the acute and chronic stages of aortic dissection during computed tomography.
The article summarizes and systematizes the experience of computed tomography diagnostics in aortic dissection based on data available in domestic and foreign publications, as well as the results of their own clinical observations. We have identified the main and secondary signs detected by computed tomography in cases of aortic dissection.
The most important and unambiguously indicative of false lumen in classical acute and chronic aortic dissection are the larger size of the false lumen, the sign of a beak and the sign of a web. Other signs, such as calcification of the aorta, changes in the curvature and thickness of the intimal medial flap, the Mercedes-Benz symptom, the presence of thrombotic masses, the characteristics of the interposition of the lumens and the wind indicator symptom are less constant, however, a careful analysis of the totality of all secondary signs allows you to give important diagnostic information and characterize as fully as possible the manifestations significant for a cardiovascular surgeon dissections of the aorta.
A cumulative analysis of computed tomographic signs in cases of aortic dissection will help a practicing radiologist not only distinguish the true lumen from the false aorta, but also determine the stage of the process based on their characteristics, which affects the tactics of complex treatment, especially with atypical dissection.
Ultrasound and computed tomography diagnostics of ovarian cyst rupture with hemoperitoneum
Authors: Sadykova Gulnaz K. , Zheleznyak Igor S. , Ryazanov Vladimir V. , Khodkevich Ilya S. , Ipatov Victor V. , Latysheva Anastasiya Ya. , Oppedisano Mikhail Giuseppe  L.
Published: May 2023

The presented article is devoted to the issue of diagnosis of rupture of ovarian cyst complicated by hemoperitoneum. Ovarian apoplexy ranks third in the structure of urgent diseases in gynecology and second among the causes of intra-abdominal bleeding. It is a sudden hemorrhage into the ovarian tissue, accompanied by a violation of the integrity of its tissue and in some cases bleeding into the abdominal cavity, may be asymptomatic or accompanied by the sudden appearance of unilateral pain in the lower abdomen. In the conditions of emergency rest during emergency diagnostics, the main advantage of ultrasound is the ability to perform in any conditions and in any condition of the patient, therefore, this method is considered in the scientific literature as the main one for the initial examination of such patients, nevertheless, in the scientific literature there is information about the differential diagnosis of emergency gynecological conditions accompanied by hemoperitoneum by X-ray computed tomography.
The article presents the signs detected during ultrasound diagnostics and computed tomography in case of rupture of an ovarian cyst, systematized on the basis of literature data and our clinical experience. The main ultrasound and CT symptoms are intraperitoneal effusion with the presence of a sentinel thrombus in the injured ovary and cystic formation in the ovary.
The combined analysis of these signs will help the practitioner in an urgent situation not only to determine the blood in the abdominal cavity, but also to determine the source of bleeding, as well as to differentiate the rupture of the ovarian cyst from other conditions accompanied by acute abdominal pain syndrome.
The Destructive Earthquake Doublet of 6 February 2023 in South-Central Türkiye and Northwestern Syria: Initial Observations and Analyses
Authors: Mai P. Martin , Aspiotis Theodoros , Aquib Tariq Anwar , Cano Eduardo Valero , Castro-Cruz David , Espindola-Carmona Armando , Li Bo , Li Xing , Liu Jihong , Matrau Rémi , Nobile Adriano , Palgunadi Kadek Hendrawan , Ribot Matthieu , Parisi Laura , Suhendi Cahli , Tang Yuxiang , Yalcin Bora , Avşar Ulaş , Klinger Yann , Jónsson Sigurjón
Published: May 2023

On 6 February 2023, two large earthquakes with magnitude 7.8 and 7.6 rocked south-central Türkiye and northwestern Syria. At the time of writing, the death toll exceeded 50,000 in Türkiye and 7200 in Syria. The epicenter of the first mainshock was located ∼15 km east of the east Anatolian fault (EAF), the second large earthquake (9 hr later) initiated ∼90 km to the north on the east–west-trending Sürgü fault. Aftershocks delineate fault lengths of ∼350 and ∼170 km, respectively. Using satellite and seismic data for first-order analyses of surface-fault offsets, space–time rupture evolution, and recorded ground motions, our study sheds light on the reasons for the extensive destruction. The first event ruptured the EAF bilaterally, lasted for ∼80 s, and created surface fault offsets of over 6 m. The second event also ruptured bilaterally with a duration of ∼35 s and more than 7 m surface offsets. Horizontal ground accelerations reached locally up to 2g in the first mainshock; severe and widespread shaking occurred in the Hatay-Antakia area with values near 0.5g. Both earthquakes are characterized by directivity effects and abrupt rupture cessation generating stopping phases that contributed to strong seismic radiation. Shaking was further aggravated locally by site-amplification effects.
The Impact of the Russia and Ukraine War on Indonesian Economic and Trade Performance
Authors: Darmawan Arif , Nairobi Nairobi , Rakhmadi Roby , Atiqasani Ghania
Published: May 2023

The Russian military invasion of Ukraine surprisingly impacted the world's geopolitical situation. The conflict that started at the end of February is ongoing, potentially disrupting economic and trade performance in the global sector, including Indonesia. The battle has the opportunity to increase some food commodity prices, thus hampering the total imports carried out. In addition, other leading commodities (non-oil and gas) such as gold, oil, and coal will also experience significant turmoil due to the conflict that has continued to heat up recently. The study provides an overview of the systemic impact on Indonesia's economic conditions by predicting the short-term possibilities. This study investigates the Russia-Ukraine conflict's initial estimate of the net import value of the two countries and other trading partners. This study uses independent variables, namely oil and gas commodities and gold prices over eleven years (2000-2021). Error Correction Model (ECM) is an analytical method used in this study. This research expects to give an overview to academia, business, industry, and the government in anticipating Indonesia's economic and trade performance to the crisis in Russia and Ukraine. Thus, it is hoped that this research can be used as an illustration of the government to make decisions in allocating import values amid the polemic between Russia and Ukraine so that trade values can be optimal.
Utilization of The Ayung Watershed (DAS) as A Sustainable Tourism Attraction In Gianyar Regency
Authors: Waridin Waridin , Astawa I Putu , Prastyadewi Made Ika , Suciati Ika , Al-Hafidz Zulfikar
Published: May 2023

This study aims to make a list of rules governing the existence and use of watersheds (DAS) in Ubud, try to internalize externalities of watershed utilization, and examine the role of stakeholders in managing watershed utilization in the tourism sector. The sample was selected through ABGC snowball sampling (Academic, Business, Government, and Community). Two types of data are used. Direct observation and in-depth interviews were used to collect primary data. Secondary data is taken from satellite imagery and MAPID.id. The analytical techniques used in this research include stakeholder analysis, descriptive analysis, and literature review. As a consequence of this study, the Tri Hita Karana idea, which was later ratified in a local regulation, was taken into consideration by the management of the Ayung Watershed in the tourism business. Rafting excursions are the only direct use of the Ayung watershed. In addition, the agropolitan and agro-tourism zones of Payangan Regency use water from the Ayung River. To combat the negative externalities associated with the use of the Ayung watershed for tourism, Tri Hita Karana is used. Stakeholders who have great influence and interest in protecting the Ayung Watershed include agriculture, LMDH Pesanggem, and Perhutani.
PEMBUATAN LEMBAR KERJA PESERTA DIDIK (LKPD) BERBASIS PROJECT DENGAN HYBRID LEARNING UNTUK PENGUATAN PROFIL PELAJAR PANCASILA
Authors: Sumarmi Sumarmi , Wahyuningtyas Neni , Putra Alfyananda Kurnia , Mutia Tuti , Wijayanto Bayu
Published: May 2023

PROJECT-BASED STUDENTS WORKSHEET TO ENHANCE STUDENTS' PANCASILA PROFILE IN HYBRID LEARNINGThe COVID-19 pandemic has had a changing impact on various aspects of life. One of them is the aspect of education which so far tends to be carried out in a conventional classical manner, which must develop towards digitalization. Therefore, this article discusses community service with the aim of improving the skills of teachers in schools under the auspices of YPK East Java in making project-based worksheets with hybrid learning to strengthen the profile of Pancasila students. The method adopted is empowerment through training and mentoring for teachers in schools under the auspices of YPK East Java with three stages namely preparation, implementation and follow-up. Based on an analytical study, the results of community service activities showed a positive impact on improving the skills of teachers in schools under the auspices of YPK East Java in making project-based worksheets with hybrid learning. Thus, teachers in schools have skills in implementing learning that is able to support strengthening the profile of Pancasila students.Pandemi COVID-19 memberikan dampak perubahan pada berbagai aspek kehidupan. Salah satunya yaitu aspek pendidikan yang selama ini cenderung dilaksanakan secara klasikal konvensional harus berkembang ke arah digitalisasi. Oleh karena itu, artikel ini membahas tentang pengabdian masyarakat dengan tujuan meningkatkan keterampilan guru-guru di sekolah yang ada di bawah naungan YPK Jatim dalam pembuatan LKPD berbasis project dengan hybrid learning untuk penguatan profil pelajar Pancasila. Metode yang ditempuh yaitu pemberdayaan melalui pelatihan dan pendampingan pada guru-guru di sekolah yang ada di bawah naungan YPK Jatim dengan tiga tahapan yaitu persiapan, pelaksanaan, dan tindak lanjut. Berdasarkan kajian analisis, hasil kegiatan pengabdian kepada masyarakat menunjukkan dampak positif pada peningkatan keterampilan guru di sekolah yang ada dibawah naungan YPK Jatim dalam membuat LKPD berbasis project dengan hybrid learning. Sehingga, guru di sekolah mempunyai ketrampilan dalam mengimplementasikan pembelajaran yang mampu mendukung penguatan profil pelajar Pancasila.
The effect of obesity on the outcome of surgical aortic valve replacement for aortic stenosis
Authors:   Faculty of Medicine, University of Iceland, Einarsdóttir Freydís Halla , Gunnarsdóttir Erla Liu Ting ,   Department of Cardiothoracic Surgery, Landspitali University Hospital, Gunnarsdóttir Sunna Lu Xi ,   Department of Cardiothoracic Surgery, Landspitali University Hospital, Jensen Elín Metta ,   Faculty of Medicine, University of Iceland, Viktorsson Sindri Aron ,   Department of Cardiothoracic Surgery, Landspitali University Hospital, Ingvarsdóttir Inga Lára ,   Anaesthesia and Intensive Care, Landspitali University Hospital, Heitmann Leon Arnar ,   Faculty of Medicine, University of Iceland, Guðbjartsson Tómas ,   Faculty of Medicine, University of Iceland, Department of Cardiothoracic Surgery, Landspitali University Hospital
Published: May 2023

INTRODUCTION: Our objective was to investigate the effect of obesity on short-term complications and long-term survival after surgical aortic valve replacement (SAVR) for aortic stenosis (AS). MATERIAL AND METHODS: A retrospective study on 748 patients who underwent SAVR for AS in Iceland 2003-2020. Patients were divided into groups based on body mass index (BMI): normal (18.5-24.9 kg/m2, n=190), overweight (25-29.9 kg/m2, n=339), obese (30-34.9 kg/m2, n=165) and severely obese (≥35 kg/m2, n=54). Six patients with BMI<18,5 kg/m2 were excluded. Clinical information regarding patient history, risk factors, together with complications and 30-day mortality were collected from patient records. The four BMI groups were compared and long-term survival estimated with Kaplan-Meier plots and risk factors for long-term survival evaluated with Cox multivariate analysis. RESULTS: Severely obese patients were on average four years younger than patients with normal BMI, more often had risk factors for cardiovascular disease, and their EuroSCORE II was higher (5.3 vs. 4.4%, p=0.03). On the other hand, severely obese patients bled less the first 24 hours post-surgery, compared to normal BMI-patients (558 vs. 1091 ml, p<0.001), stroke was less frequent (0 vs 6.4%, p=0.03), but they more often experienced sternum dehiscence (5.6 vs 2.7%, p=0.04), deep sternal wound infection (3.7 vs 0%, p=0.04) and acute kidney injury (26.4 vs 15.2%, p=0.005). Thirty-day mortality and long-term survival did not differ significantly between the groups and BMI was not an independent predictor of long-term survival in multivariate analysis. CONCLUSIONS: The outcome for obese patients undergoing SAVR for AS is good and both short-term complications and long-term survival do not differ significantly from patients with a normal BMI. Therefore, a high BMI itself should not be a contraindication for SAVR due to AS.
The incidence of postoperative and persistent usage of proton pump inhibitors following surgery
Authors:   University of Iceland, Kristjánsdóttir Thelma Rós , Sigurðsson Martin Ingi ,   Landspitali, University hospital, Faculty of Medicine, University of Iceland, Jónsdóttir Freyja ,   Landspitali University Hospital, Faculty of Pharmaceutical Sciences, University of Iceland
Published: May 2023

INTRODUCTION: The use of proton pump inhibitors (PPI) has increased over the past decades. Some patients use the medication without an indication. It is possible that new use will start following surgery. The study aimed to examine the incidence of postoperative use of PPI following surgeries and the ratio of new persistent users over three months postoperatively as well as patient- and procedural variables associated with new use and new persistent use. METHODS: Data of surgeries among adults that had undergone surgeries at the National University Hospital of Iceland from 2006 to 2018. The data were from the Icelandic perioperative database, containing information regarding medication usage preceding and following surgeries. The ratio of those who started using PPI within three months of surgery was assessed, and the ratio of persistent users. RESULTS: Altogether, 2886 out of 42.530 patients filled PPI prescription within three months after their first surgery. Annual incidence was 67 per 1.000 surgeries, and the ratio of persistent users was 54%, although both the varied between years. The use was more common among women, highest in age group 56-65 years old, patients with polypharmacy (5-9 medicines) and who underwent abdominal surgeries. CONCLUSIONS: New postoperative PPI use is common following surgery and half of the patients with new use develop new persistent use. The usage increased similar to the increased number of prescriptions and sales of PPI in other patient groups during the period. The results indicate the need for further monitoring of patients with PPI prescriptions following surgeries in Iceland.
Attitudes towards COVID-19 vaccination, vaccine hesitancy and vaccine literacy among unvaccinated young adults
Authors: YILMAZEL Gulay , KELES Emre , CALMAZ Ayse , DAYSAL GULER Burcu
Published: May 2023

BackgroundHerd immunity is necessary to control the coronavirus disease 2019 (COVID-19) pandemic. Unfortunately, attaining herd immunity is a significant challenge for current healthcare systems worldwide, and the prevalence of hesitancy toward COVID-19 remains high. The aim of this study was to determine pandemic vaccine hesitancy, attitudes towards COVID-19 vaccine and COVID-19 vaccine literacy level in vaccination period among unvaccinated young adults.
MethodsThis cross-sectional study was carried out in the province of Çorum in Turkey. Unvaccinated young adults (n=860) between the ages of 18-30 studying medicine and non-medical sciences of a university were included in the study. Socio-demographic form, and the scales on Pandemic Vaccine Hesitancy, Attitudes towards the COVID-19 vaccine, COVID-19 vaccine literacy were used to collect the research data. The data were analyzed using percentages, median values, regression analysis.
Results The study was completed with 860 participants. In the group, 73.8% were 18-24 years 67.7% were women and 68.0% were infected with the virus. The median scores from the pandemic vaccine hesitancy scale, vaccine literacy and vaccine attitudes were 33, 27 and 30 respectively. Use of social media in daily, vaccine literacy and COVID-19 vaccine attitude were effective factors on pandemic vaccine hesitancy (p<0.05). Negative attitude to vaccines was the most influenced risk factor of vaccine hesitancy (Beta = 0.248).
ConclusionPandemic vaccine hesitancy is a phenomenon that coincides with low vaccine literacy and negative attitudes towards vaccines. COVID-19 vaccination information campaigns should promote group strategies, focusing on emphasising the safety of the vaccine and offer reassurance.
Reversible ethambutol-induced optic neuropathy: report of a rare case
Authors: Nusanti Syntia , Putri Rasyidia Laksmita , Dearaini Dearaini
Published: May 2023

BackgroundEthambutol (EMB) is one of the first-line anti-tuberculosis therapy. One of its precarious side effects is ethambutol-induced optic neuropathy (EON). The ocular manifestations of EON include painless loss of central vision and cecocentral scotomas in the visual field.
Case DescriptionA 60-year old man presented with gradual and painless visual loss since 3 months prior to visit. The accompanying symptoms were frequent headache without double vision and photophobia. He had been diagnosed with pulmonary tuberculosis (TB) for 9 months and consumed EMB for 7 months before being advised to discontinue. There was neither history of systemic diseases nor family history of neuropathy. Examination showed reduced visual acuity with positive relative afferent pupillary defect (RAPD) on right eye. Humphrey test showed bilateral generalized visual loss. Ocular computed tomography (OCT) showed retinal nerve fiber layer (RNFL) thickness was within normal limit. Magnetic resonance Imaging (MRI) brain indicated unremarkable result for optic neuropathy. Based on the examinations listed above, this patient was diagnosed as EON and EMB was stopped immediately. Patient was given oral citicoline 1000mg and zinc supplementation for one month. After 1 st and 3 rd month follow up, patient’s visual function was gradually improved. The ophthalmic examinations indicated recovery of the visual function.
ConclusionsThis case suggested that an early detection and intervention in patient with EON has promising result in visual outcome. EON is a reversible optic neuropathy if the ocular toxicity is monitored closely among the tuberculosis patients who are prescribed EMB regiment.
Does employee trust matter? Measuring the effect of work engagement on turnover intention in the banking sector
Authors: Malik Nazaruddin
Published: May 2023

Research aims: This study examines the effect of work engagement on the turnover intention with employee trust as a mediating variable in the banking sector in Malang, IndonesiaDesign/Methodology/Approach: This study uses a quantitative approach with data collection methods using questionnaires that were distributed online and processed using Partial Least Square (PLS) using a 119 response data.Research findings:  The findings of this study show that work engagement has a negative effect on turnover intention. Employee trust mediated the effect between work engagement and turnover intention.Theoretical contribution/Originality: This study examined the role of employee trust as a mediating variable. Employee trust plays a vital role in maintaining people’s engagement on an organization, affecting low workers' intention to quit from their jobs. The results of this study confirm Maslow's motivational theory if employees are more involved in work and feel fulfilled. Employees will feel comfortable and reduce the level of turnover intention.Practitioner/Policy implication: These findings suggested leaders encourage engagement programs to increase employee trust to reduce turnover intention.Research limitation/Implication: The study had limitations, such as the few samples used and the fact that only Malang's banking industry employees were included.
Cenários para a implementação de políticas de segurança da informação em universidades públicas federais
Authors: Araújo Wagner Junqueira de , Araújo Sueny Gomes Léda , Batista Rafaela Romaniuc
Published: May 2023

As políticas de segurança da informação consistem em importantes normas para a eficiente gestão da informação nas Universidades Públicas Federais. Tomando como base essa premissa, esta pesquisa teve como objetivo prospectar cenários sobre a implementação e aplicação das políticas de segurança da informação em universidades públicas federais no período entre 2018 a 2022. Diante dos variados métodos de prospecção de cenários, optou-se pelo método preconizado por Michel Godet por tratar-se de um método estruturado para elaboração de cenários exploratórios descritivos e por possuir um conjunto de ferramentas de software que auxilia na prospecção de cenários. A pesquisa buscou aplicar duas fases do método: a primeira, análise estrutural, que visou obter uma representação possível do sistema em estudo, bem como reduzir a complexidade em variáveis-chave, por meio da ferramenta MICMAC; a segunda fase, análise estratégica de atores, foi realizada nos atores “motores”, os que comandam as variáveis-chave identificadas na análise estrutural. Essa fase foi realizada com apoio da ferramenta MACTOR. Para a aplicação do processo proposto, foram utilizados os instrumentos: brainstorming, consulta aos especialistas, pesquisa bibliográfica e reuniões. Com o resultado da análise estrutural e da análise das estratégias dos atores, foi projetado três cenários possíveis sobre políticas de segurança da informação em universidade públicas federais, evidenciando tendências ou rupturas. Observa-se que realizar a prospecção sobre a implementação dessas políticas pode auxiliar as administrações na construção de processos de gestão de segurança da informação baseados em modelos de governança, por meio de cenários alinhados às tendências sem esquecer as rupturas.
Importance of soft tissue ?njuries in the facial area in terms of criminal law and compensation for bodily damages
Authors: Dalgic Sertac , Gulderen Abuzer , Cetin Selcuk
Published: May 2023

Skin injuries in the face area are one of the common causes of admission to the emergency department and the treatment to be applied affects whether or not there will be any scars. In the legal system, fixed facial scar is given great importance and it is an aggravating factor in criminal law. However, it is seen that the permanent scars formed on the face as a result of trauma do not have an exact equivalent in the disability determination charts. In our study; in the disability detection regulations, it was tried to determine the deficiencies related to permanent scars in the face area and it was aimed to raise awareness about this issue.

We analyzed 1972 cases that applied for disability assessment and were examined and reported by us. With the trauma in his body that is the subject of the report 302 cases with a causal trace were included in the study.

It was observed that 212 (70%) of 302 cases with facial trauma-related scars received a rate from one of the disability determination charts. It was determined that 90 (30%) cases did not receive a rate.

Conclusion: The emergency physician who first encounters the trauma patient should apply the treatment methods that can achieve the best aesthetic results in a patient who is admitted to the hospital due to facial injury and take all kinds of measures to reduce the possibility of remaining scars. We think that there should be a section that specifies exactly the rate to be given by classifying permanent scar wounds in the face area according to various features, by updating the scales used in disability determination procedures.
Timely Development: Visualizing Childrenâ€™s Growth and Potential
Authors: McCarthy Annie
Published: May 2023

Childrenâ€™s growth has long been measured against the axis of time. Yet anthropometric indexes such as age for height measurements do not simply mark the passage of time and associated growth but themselves indicate â€œnormsâ€ that stand as markers of potential. Charting changing modes of representing the problem of childrenâ€™s growth over the 20th century and into the 21st, this paper attends to visual technologies that distribute potential unevenly around the world, asking what is at stake in making childrenâ€™s growth and development visible, and whose potential is affirmed in the process?
Environmental sustainability disclosure in sustainability reports: Mining, oil, and gas companies on the Indonesia stock exchange
Authors: Agung Ulupui I Gusti Ketut , Muhammad Zairin Gentiga , Michael Musyaffi, Ayatulloh
Published: May 2023

This paper examines how mining, oil, and gas companies address environmental issues and communicate their actions to stakeholders through sustainability reports. Using market capitalization as a size metric, 50 mining, oil, and gas companies listed on the Indonesia Stock Exchange (IDX) were included in the research sample. Sustainability reports were subjected to quantitative and qualitative content analysis to identify keyword occurrences that were pertinent to the investigation. The findings revealed that environmental protection, emissions, carbon footprint, climate change, biodiversity, nature, planet, effluent, and conservation were addressed in the companies’ sustainability reports. This study confirmed, in line with research on other industries, that the intensity of communication on these topics varies with company size. It was also found that, although some companies discuss many keywords that correspond to the Global Reporting Initiative, they are irrelevant because the reports do not show the companies’ commitment and efforts to achieve the concepts. The practical implication of this research is that companies should show more commitment in their efforts to address environmental issues – sustainability disclosure is not just about words.
Los textos manuscritos de Guaman Poma (II). Las etapas de la evolución del manuscrito Galvin de la Historia general del Perú de Martín de Murúa
Authors: Boserup Ivan
Published: May 2023

Existen hoy dos manuscritos originales de la obra historiográfica del misionero español Martín de Murúa: el Getty y el Galvin. El manuscrito Getty, según su portada, data de 1613, y el manuscrito Galvin presenta la fecha de 1590, pero data de 1596 o 15971 • El manuscrito Getty tiene un volumen dos veces mayor que el del Galvin. Pese a que estos dos manuscritos llevan títulos diferentes, son variantes de una obra única, ampliada y reorganizada en varias ocasiones. El Getty lleva en su portada el título Historia general del Piru2 • Tal y como se los conocen hoy, ambos manuscritos están ilustrados con dibujos a color, treinta y ocho en el Getty, ciento doce en el Galvin. Algunos de ellos (en ambos manuscritos) fueron creados por el propio Guarnan Poma, el autor-artista de la Nueva corónica y buen gobierno (1615). Tres de sus dibujos se encuentran en el Getty, casi cien en el Galvin.
El capitán, el ermitaño y el cronista. Claves para establecer cuándo nació el autor de la Nueva corónica y buen gobierno
Authors: de la Puente Luna José Carlos
Published: May 2023

El padre Ayala dormía poco pero soñaba mucho, a veces con los ángeles. Al alba, el canto del gallo le indicaba que había pasado la noche atado a su cabecera que ya era tiempo para la primera oración. El padre se levantaba de la estera de paja y, mientras completaba sus rezos en su celda del Hospital de Naturales de Huamanga, pájaros y ratones acudían a acompañarlo y a recibir su bendición -al menos así lo aseguraban algunos-. Enseguida, Martín iniciaba su ronda de visitas entre los enfermos y desahuciados del hospital. Nunca se reía ni miraba a las mujeres a los ojos, evitaba pronunciar malas palabras y concebir malos pensamientos, celebraba misa todos los días, condenaba el trato cruel hacia cualquier ser animado y repartía su corto caudal entre los pobres y necesitados de la ciudad. A pesar del frío, jamás traía camisa bajo el hábito -aunque un cilicio lo acompañaba a todo lugar-. Generoso, humilde y hasta milagroso era el padre Ayala. Un retrato de este santo hombre colgaría pronto de una de las paredes del Hospital de Naturales.
Importancia de los enanos y corcovados en la Nueva corónica
Authors: Holland Augusta E.
Published: May 2023

Debido a que el parasol es un objeto de origen asiático, erróneamente considerado como nativo peruano, uno debe preguntarse cómo llegaron al Perú las imágenes de este objeto utilitario. Los dibujos de enanos y corcovados sosteniendo parasoles en la Nueva corónica son importantes porque demuestran que los recursos visuales utilizados en la crónica son abundantes, variados y van más allá de Europa. Imágenes de este tipo, oriundos del manuscrito Galvin mayormente ilustrado por Guarnan Poma, también aparecen en la Historia general del Perú (hacia 1611-1613), de Martín de Murúa, crónica estrechamente ligada con la Nueva corónica. Más aun, las imágenes de enanos y corcovados con parasoles en estas dos crónicas son las representaciones más tempranas de esta naturaleza que aparecen en el arte del virreinato del Perú. Durante la segunda parte del siglo XVII, retratos de la realeza inca y sus descendientes fueron rutinariamente pintados protegidos bajo parasoles sostenidos por sirvientes enanos corcovados. El propósito de este ensayo es, por consiguiente, trazar la posible trayectoria de estas imágenes de Asia al Nuevo Mundo. Basaré mi trabajo en dos eventos históricos importantes que ocurrieron durante la vida de Guarnan Poma. Uno es la apertura por los españoles de la ruta transpacífica, la cual les permitió conectar todas las regiones de su imperio con Asia y el segundo son las actividades misionales de los jesuitas en Japón antes de 1600, es decir, dieciséis años antes de que Guarnan Poma de Ayala terminara y enmendara su Nueva corónica.