bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of serum oxidative stress markers among male partners of fertile and infertile couple at Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria
Authors:   Department of Chemical Pathology Nnamdi Azikiwe University, Nnewi campus, Nnewi, Anambra State, Nigeria, Donatus Okafor Chidimma , Chukwuemeka Meludu Samuel ,   Department of Human Biochemistry, Nnamdi Azikiwe University, Nnewi campus, Nnewi, Anambra State, Nigeria, Kester Nwaefulu ,   Department of Human Physiology Nnamdi Azikiwe University, Nnewi campus, Nnewi, Anambra State, Nigeria, Ifeanyichukwu Ikechebelu Joseph ,   Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Nnewi campus, Nnewi, Anambra State, Nigeria, Emmanuel Dioka Chudi ,   Department of Chemical Pathology Nnamdi Azikiwe University, Nnewi campus, Nnewi, Anambra State, Nigeria, Ugochukwu Obi ,   Department of Chemical Pathology, Nnamdi Azikiwe University, Nnewi campus, Nnewi, Anambra State, Nigeria
Published: May 2022

Infertility is a common cause of marital disharmony in Nigeria because of the high premium placed on child bearing. Male factor is a significant contributor and declining male fertility rate has been observed over the past decade. Oxidative stress has been implicated in the aetiology of male infertility. The objective of the study was to compare the serum levels of oxidative stress markers (TAC – Total Antioxidant Capacity, MDA - Malondialdehyde and SOD – Superoxide dismutase) in male partners of fertile and infertile couples. This was a case controlled study carried out over a period of 8 months on male partners of infertile couple. Thirty-six were male partners of fertile couple with normal semen parameters and no history of infertility while 73 were male partners of infertile couple which consists of 28 males with oligospermia, 28 with oligoasthenospermia and 17 with asthenospermia.. Serum markers of oxidative stress (TAC, MDA and SOD) were evaluated and compared among the group. The male partners of infertile couple showed significantly low levels of TAC (P = 0.000), SOD (P = 0.000) and significantly high levels of MDA (P = 0.000) when compared with male partners of fertile couple (750.93±146.37 versus 1269.20±330.79, 11.22±3.33 versus 13.96±1.38 and 2.48±1.20 versus 1.51±0.19). Oxidative stress may be a major contributor to male infertility. Its assay may be of importance in prevention and treatment of male infertility.
Resource addition to leather industry: Adhesive from chrome shaving dust
Authors:   Institute of Leather Engineering and Technology, University of Dhaka, Dhaka-1209, Bangladesh, Shaikh Md. Aftab Ali , Deb Amal Kanti ,   Institute of Leather Engineering and Technology, University of Dhaka, Dhaka-1209, Bangladesh, Akter Eama ,   Institute of Leather Engineering and Technology, University of Dhaka, Dhaka-1209, Bangladesh, Ferdous Tasnimul ,   Institute of Leather Engineering and Technology, University of Dhaka, Dhaka-1209, Bangladesh, Mia Md. Abu Sayid ,   Institute of Leather Engineering and Technology, University of Dhaka, Dhaka-1209, Bangladesh
Published: May 2022

Leather industry produces a prodigious amount of wastewater and solid wastage containing a significant amount of hazardous chromium. Chrome Shaving Dust (CSD) is tanned collagenous micro-fine solid particulate impregnated with chromium synthetic fat and oil, tanning agents and dye chemicals. Contrariwise, the adhesive is a material which is used for bonding two or more materials together. This study will reflect the way of eliminating the CSD as a pollutant in leather industry rather it will show its lucrative function by making adhesive which is used in various footwear industries. In such way, it not only saves the environment but also aids to gain marginal profit. The process includes treating the shaving dust with distilled water, magnesium oxide and trypsin enzyme followed by force filtration, heating, evaporating, copolymerization with acrylic resin, polyvinyl alcohol, compounding with polyvinyl acetate, glycerol, Busan bactericide, and Busan fungicide. After that produced adhesive was applied in various parts of footwear to assess its function. The study not only tells about the ethical manufacturing and waste management process but also emphasizes on resource management. This considerably shows the waste generation process and also shows its alternate application in another field rather than polluting environment deliberately. Decaying ecology may get its balance with all natural species by controlling the wastes as well as its implication in an alternative way.
Immune Responses to Animal Trypanosomosis: A Review
Authors:   School of Veterinary Medicine, Wolaita Sodo University, Ethiopia, Awukew Addisu , Terefe Getachew ,   College of Veterinary and Agriculture, Addis Ababa University, Bishoftu, Ethiopia, Demisie Tilaye ,   College of Veterinary and Agriculture, Addis Ababa University, Bishoftu, Ethiopia, Eshetu Eyob ,   School of Veterinary Medicine, Wolaita Sodo University, Ethiopia
Published: May 2022

The aim of this document is to review the current knowledge on Trypanosome parasites of animals with emphasis on the immunological response and points to the wealth of information available for trypanosomiasis, in contrast to the numerous gaps in our understanding of immune responses to trypanosomal infections. African trypanosomes are pathogens for humans and livestock. They are single-cell, extra-cellular parasites that cause persistent infections of the blood and induce profound immune-suppression. The specific immune response to the infecting parasites is complex and involves both the humoral and cellular branches of immune systems. In trypanosomosis, parasite growth is primarily controlled through T-cell dependent antibody responses to the variable surface glycoproteins and possibly to other molecules embedded on the surface of the parasites. Cellular immune responses also occur but at the level of immune-suppression directed against B cells. Additionally, a variety of immune-modulatory cytokines like TNF-α, IFN-γ, IL-10, IL-4, IL-6, IL-12 and etc are produced during the course of infection. The center of the immune-pathology is the T-cell-independent production of antibodies to the variant surface glycoprotein of trypanosomes, the anti-VSG antibody-mediated phagocytosis of trypanosomes by macrophages, and the subsequent profound dysregulation of the macrophage system. It has, however, been demonstrated that a T-cell subset is critical in protective immunity.
A review of pharmacognostic, physicochemical, phytochemical and pharmacological studies on Ficus bengalensis L.
Authors:   Faculty of Pharmacy, Bahauddin Zakariya University Multan, Pakistan, Khaliq Hafiz Abdul
Published: May 2022

Since the birth of humans on this planet, plants have been utilized for diagnosis, treatment and prevention of various ailments. Ficus bengalensis L., belonging to family Moraceae, commonly known as Banyan tree, is one the most utilized plants. It is a very large tree with spreading branches bearing multiple aerial roots hanging downward. In traditional systems of medicines, various plant parts such as stem bark, aerial roots, vegetative buds, leaves, fruits and latex are used in diabetes, dysentery, seminal weakness, menorrhagia, leucorrhoea, erysipelas, nervous disorders, burning sensation, hemorrhages and applied topically on pimples, abscesses, wounds, ulcers, sores, cracked soles of the feet and rheumatic inflammations. Pharmacognostic studies have been done to set its quality control parameters and various phytochemicals viz. phytosterols, anthocyanidin derivatives, fatty acids, amino acids, polysaccharides, flavonoids, flavonols, leucoanthocyanidins and triterpenoids have been identified and isolated. This plant is reported to possess many useful pharmacological activities also viz. antihyperglycemic, antidiabetic, Antihyperlipidemic, hypocholesterolemic, anti-inflammatory, analgesic, antibacterial, antifungal, larvicidal, anti-diarrhoeal, antimutagenic, antioxidant, cytotoxic, hepatoprotective, anti-arthritic, antiallergic and immunostimulatory. The present review is an effort to give a detailed survey of the literature on its ethnomedical uses, pharmacognosy, physicochemical parameters, phytochemistry, pharmacological studies and other commercial uses.
Trikadu for obesity: Can you believe it?
Authors:   Dr. JRK’s Research & Pharmaceuticals Pvt. Ltd., No.18 & 19 Perumal koil Street, Kunrathur, Chennai, Tamil Nadu- 600069, India, Soundharya R , Kalpana T ,   Dr. JRK’s Research & Pharmaceuticals Pvt. Ltd., No.18 & 19 Perumal koil Street, Kunrathur, Chennai, Tamil Nadu- 600069, India, Aruna V ,   Dr. JRK’s Research & Pharmaceuticals Pvt. Ltd., No.18 & 19 Perumal koil Street, Kunrathur, Chennai, Tamil Nadu- 600069, India, Gayathri R ,   Dr. JRK’s Research & Pharmaceuticals Pvt. Ltd., No.18 & 19 Perumal koil Street, Kunrathur, Chennai, Tamil Nadu- 600069, India
Published: May 2022

A well-known and therapeutically effective sastric drug- Trikadu was subjected to further research to unravel its hidden efficacy in the management of obesity. We have employed the lipolytic assay technique to establish the above effect. Trikadu as finished product and the individual herbs in the formulation, both showed lipolytic activity. Trikadu is known to have therapeutic effect in the management of respiratory infection, induce digestion and appetite. The anti-obesity property assumes great importance where the Trikadu drug even when induce appetite and digestion control obesity. Findings are presented in the paper.
A comparative analysis of quality of reporting statistics in two Indian journals
Authors:   MBBS, MD, Department of Pharmacology, Topiwala National Medical College & BYL Nair Charitable Hospital, Mumbai Central, Maharsthra, India, N Mehta Manthan , P Nerurkar Rajan ,   MD, Department of Pharmacology, Topiwala National Medical College & BYL Nair Charitable Hospital, Mumbai Central, Maharsthra, India
Published: May 2022

Purpose: The importance of statistical analysis in medical research papers is ever increasing, hence, evaluation of statistical validity is crucial when evidence based medicine is highly valued. Studies with poor methodological quality and poor statistics cannot prove or disprove study hypothesis with certainty. This study was designed to evaluate, analyze and compare the reporting of statistical methods and errors in articles published in Indian Journal of Pharmacology (IJP) and Journal of Association of Physicians of India (JAPI). Materials and Methods: All original articles published in IJP and JAPI from January 2009 to September 2014 were reviewed and evaluated by using a checklist which included type of statistical test, common errors, etc. The statistical software used for analysis of data in these articles were also reviewed. Results: Three hundred articles (IJP=154; JAPI=146) were reviewed. The most commonly used statistical test in IJP was one-way ANOVA (53.8%) as compared to Chi-square test (50.6%) in JAPI. The statistical software used for analysis was mentioned in 43.5% and 50.7% articles published in IJP and JAPI respectively. The most commonly used software was GraphPad Prism (66.4%) in IJP and SPSS (67%) in JAPI. Statistical errors as per the checklist were more common in JAPI (63.5%) as against 49% in IJP. Use of mean+SE instead of Mean+SD was the most common statistical error in IJP (51.9%) whereas failure to mention the type of 't' test was the most common error (38%) in JAPI. Conclusion: Statistical errors are common in IJP as well as JAPI. To elevate the quality of articles published in Indian journals, every article must be sent for statistical review.
Development of a chemometric method for the analysis of Sudan III-IV dyes adulteration in chili powder using UV-visible spectroscopy data
Authors:   Department of Applied Chemistry and Chemical Engineering, University of Dhaka, Dhaka-1000, Bangladesh, Islam Md. Faizul , Uddin Mohammad Nashir ,   BCSIR Laboratories, Dhaka, Bangladesh Council of Scientific and Industrial Research (BCSIR), Dhaka-1205, Bangladesh, Rana Ashequl Alam ,   Department of Applied Chemistry and Chemical Engineering, University of Dhaka, Dhaka-1000, Bangladesh, Karim Mohammad Mainul ,   Department of Applied Chemistry and Chemical Engineering, University of Dhaka, Dhaka-1000, Bangladesh
Published: May 2022

Chili powder is a globally traded commodity and one of the most important parts of regular diet of the people of Bangladesh. It is reported that chili power has been adulterated by Sudan III-IV dyes since 2003. A simple, fast and cost effective method for the identification of Sudan dyes (III and IV) present in chili powder was proposed here and the method was based on the characterization of UV-visible spectral data using artificial neural network (ANN). Artificial neural network (ANN) was developed for the simultaneous assay of chili powder adulterated with Sudan III-IV. 47 standard mixture solutions were prepared using orthogonal experimental design (OED) to build a calibration data set. UV-visible spectra of these mixtures were obtained between 200 and 800 nm at 1 nm interval. The results of the artificial neural network were compared with that of other two calibration techniques namely, principal component regression (PCR) and partial least square regression (PLSR). ANN shows better prediction efficiencies comparing with PCR and PLSR. Prediction by ANN on the basis of spectroscopic data is 85% for chili powder, 70% for Sudan III and 60% for Sudan IV in terms of coefficient of determination (R2 ). Six different branded chili powders collected from the local market, and were measured by using the proposed method. It was found that no samples contained Sudan III-IV. So, the proposed method can be easily used in the quality control of any chili powder adulterated with Sudan IIIIV dyes as an alternative analysis tool.
Inflammatory Skin diseases in HIV infected children at Ladoke Akintola University Teaching Hospital, Osogbo, Nigeria
Authors:   Consultant Paediatrician, Department of Paediatrics & Child Health, Ladoke Akintola University of Technology Teaching Hospital, Osogbo, Osun State, Nigeria, Adetuji Oyedeji Olusola
Published: May 2022

Background: Reports on inflammatory skin manifestations of HIV are scarce in Nigerian children, considering the fact that they are common and indicative of underlying HIV disease staging or progression. Thus, the aim of this study was to determine the prevalence, types and distribution of inflammatory skin lesions amongst HIV infected Nigerian children. Method: All the children attending the paediatric anti-retroviral clinic of Ladoke Akintola University of Technology (LAUTECH) Teaching Hospital, Osogbo. were studied. Inflammatory cutaneous lesions of HIV were identified from clinical examination. Socio-demographic, clinical and laboratory details were also obtained. Data was analyzed with SPSS version 19 software. Results: Of the 102 children studied 25(24.5%) had inflammatory skin lesions. The age of the children studied ranged between 3months and 14years. Papular urticaria, Papular pruritic eruptions, Seborrhoeic dermatitis, Angular stomatitis, Milaria and Acne were found in 9(8.8%), 8(7.8%), 3(2.9%), 2(2.0%), 1(1.0%) and 1(1.0%) cases respectively. Inflammatory skin diseases were significantly reduced among children on HAART compared to those yet to initiate HAART. (P = 0.02, O.R = 0.29, 95% = C.I 0.11 - 0.81). Conclusion: Inflammatory skin diseases are not uncommon among the group studied with, papular urticaria and papular pruritic eruptions being the most common inflammatory skin disease in HIV infected children. Administration of HAART is associated with significantly reduced skin disease.
دور إدارة سلسلة التوريد في تعزيز جودة الخدمات المقدمة (دراسة ميدانية على مؤسسات الطوافة)
Authors: الخديدي عبد الإله بن عيضه رده
Published: May 2022

هدفت الدراسة إلى معرفة دور إدارة سلسلة التوريد في تعزيز جودة الخدمات المقدمة في مؤسسات الطوافة في مكة المكرمة. ولتحقيق أهداف الدراسة استخدم الباحث المنهج الوصفي التحليلي، وتمثل مجتمع الدراسة العاملين في مؤسسات الطوافة، وتم اختيار عينة الدراسة بالطريقة العشوائية البسيطة، وبلغ عددهم (138) موظف. وأظهرت نتائج التحليل الإحصائي أنه توجد علاقة ذات دلالة إحصائية عند مستوى دلالة (0.05 ≤ α) بين إدارة سلسة التوريد وتعزيز جودة الخدمات المقدمة، وتبين أن المتغيرات المستقلة المؤثرة في جودة الخدمات المقدمة هي: "التوريد، التخزين"، بينما تبين عدم وجود تأثير لمتغير النقل. وقد أوصت الدراسة مؤسسات الطوافة بالاهتمام بمجال النقل وكذلك الاهتمام بجودة الخدمات المقدمة.
مواءمة الخطة الاستراتيجية لجامعة السلطان قابوس لمتطلبات الثورة الصناعية الرابعة
Authors: الصيعرية مشاعل عوض
Published: May 2022

هدفت الدراسة الحالية للكشف عن مدى مواءمة الخطة الاستراتيجية بجامعة السلطان قابوس لمتطلبات الثورة الصناعية الرابعة، والتوصل لعدد من المقترحات لتطوير الخطة الاستراتيجية للجامعة في ضوء متطلبات الثورة الصناعية الرابعة. استخدمت الدراسة المنهج النوعي لملائمته لأهداف الدراسة من خلال إجراء المقابلات وتحليل المحتوى، وقد تكونت عينة المقابلات من 9 أفراد من قيادات جامعة السلطان قابوس، أما عينة تحليل المحتوى فقد شملت الخطة الاستراتيجية للجامعة 2016-2040. توصلت نتائج الدراسة إلى وجود مؤشرات لمتطلبات الثورة الصناعية الرابعة في الخطة الاستراتيجية للجامعة بشكل جيد، كما وأشارت نتائج الدراسة إلى أن مستوى مواءمة الخطة الاستراتيجية للثورة الصناعية الرابعة كانت جيدة بحسب وجهة القيادات العليا فيها. كما قدمت الدراسة عددًا من الإجراءات المقترحة لتفعيل التخطيط الاستراتيجي بجامعة السلطان قابوس في ضوء الثورة الصناعية الرابعة تتمثل في بناء القدرات والمهارات، تفعيل الخطط لمواكبة الثورة الصناعية الرابعة، وبناء الشركات المجتمعية، وتعزيز البحث العلمي.
العلاقة بين الرشاقة الاستراتيجية والقدرة على إدارة الأزمات في الجامعات السعودية "دراسة تطبيقية على جامعة الملك خالد"
Authors: ال يحي نجلاء غازي حامد , عبد القادر سليم برشيد
Published: May 2022

هدفت هذه الدراسة إلى معرفة العلاقة بين الرشاقة الاستراتيجية والقدرة على إدارة الأزمات لدى موظفي جامعة الملك خالد. ولتحقيق أهداف الدراسة استُخدم المنهج الوصفي التحليلي، كما عُملت استبانة إلكترونية مكونة من (52) فقرة وزعت على (207) من الموظفين ومنسوبي جامعة الملك خالد، وقد أظهرت الدراسة عدة نتائج أهمها وجود تأثير معنوي ذو دلالة إحصائية على المتغير التابع (إدارة الأزمات) حيث كان مستوى الدلالة لها أقل من 5% في المحاور الأربعة. وكان ترتيب إدراج عوامل ممارسات الرشاقة الاستراتيجية الأربعة في معادلة الانحدار كالتالي، محور التنظيم، محور الأفراد، محور التخطيط، محور التكنولوجيا كما قدمت الدراسة مجموعة من التوصيات أهمها ضرورة أن تكون جامعة الملك خالد سباقة للتغير بدلًا من اللجوء إلى ردة الفعل من أجل التصدي بسرعة وفعالية من خلال الالتزام بممارسات الرشاقة الاستراتيجية على مستوى التخطيط والتنظيم. وكذلك تبني مؤشرات داخلية لرصد الأزمات وذلك كما هو معروف أن الأزمات ترسل إشارات قبل حدوثها فلذلك يمكن الاستفادة من هذه الإشارات من أجل الوقاية من الأزمات ويمكن تطبيق مرحلة الرصد من خلال إجراء مسح شامل للبيئة الداخلية والخارجية.
دواعي هجرة الموارد البشرية في فلسطين من وجهة نظر الطلبة الجامعيين
Authors: شحادة سونيا عبد الفتاح
Published: May 2022

هدفت الدراسة التعرّف إلى دواعي هجرة الموارد البشرية في فلسطين من وجهة نظر الطلبة الجامعيين، وبحثت في دور متغيرات: الدرجة العلمية، ومكان السكن، والمستوى الدراسي في تحديد وجهة نظر الطلبة حول موضوع الدراسة. ولتحقيق أهداف الدراسة تم استخدام المنهج الوصفي، حيث قامت الباحثة بتطوير استبانة مكونة من (30) فقرة تقيس دواعي هجرة الموارد البشرية في فلسطين من وجهة نظر الطلبة الجامعيين. وتكوّن مجتمع الدراسة من جميع طلبة جامعة فلسطين التقنية خضوري/ فرع رام الله في الفصل الثاني للعام الدراسي 2019-2018، إذ بلغ عددهم )1200( طالبًا وطالبة، وتم اختيار عينة طبقية تكونت من )250( طالبًا وطالبة، بينت نتائج الدراسة أن وعي الطلبة الجامعيين حول دواعي هجرة الموارد البشرية في فلسطين جاءت بدرجة متوسطة، كما دلت على عدم وجود فروق دالة إحصائيًا تعزى لمتغيريّ النوع والمستوى الدراسي، في حين دلت على وجود فروق دالة إحصائيًا تعزى لمتغير الدرجة العلمية ولصالح مستوى البكالوريوس، وعلى وجود فروق دالة إحصائيًا تعزى لمتغير مكان السكن بين طلبة المدينة والقرية والمخيم ولصالح طلبة المخيم، في ضوء نتائج الدراسة أوصت الباحثة ضرورة إشغال الوظائف بما يناسبها من الكوادر البشرية من ناحية علمية ومهارية، كذلك العمل على محاربة الفساد الإداري للقضاء على المحسوبية والوساطة لضمان التوظيف بناء على الكفاءة، والعمل على تحسين مستوى الدخل وتقدير دور الكفاءات البشرية في عملية التنمية.
قياس مستوى جودة الخدمات المدركة والمتوقعة في الحرمين الشريفين في ظل جائحة كورونا من خلال نموذج (SERVQUAL)
Authors: الحربي بدرية دخيل ماطر
Published: May 2022

هدفت الدراسة إلى التعرف على مستوى جودة الخدمات المقدمة المدركة والمتوقعة في الحرمين الشريفين في ظل جائحة كورونا من وجهة نظر المستفيدين من الحجاج والمعتمرين والزوار، واتبعت الدراسة المنهج الوصفي التحليلي، باستخدام الاستبانة التي طبقت على العينة، وقد أظهرت النتائج أن أفراد العينة موافقين بشدة على فقرات بعد الملموسية مثل (التجهيزات والمعدات والبرمجيات ومواقف السيارات ومظهر الحرمين العام) من مقياس (SERVQUAL) كما أظهرت أيضًا انهم موافقين بدرجة كبيرة جدًا على مدى توفر الاعتمادية بالحرمين الشريفين على حسب مقياس (SERVQUAL) وتتمثل في (قيام الرئاسة العامة لشئون الحرمين الشريفين بتقديم الخدمات بالشكل الصحيح وفي الوقت المناسب في بداية أثناء جائحة كرونا) كأحد أهم عناصر الاعتمادية، وأوصت الدراسة بضرورة المحافظة عل مستوى جودة التكييف والتهوية الصحية في الحرمين الشريفين خدمة للحجاج والمعتمرين والزوار للحرمين الشريفين، كما أوصت بزيادة معدلات تنفيذ أعمال النظافة داخل الحرمين الشريفين أثناء جائحة كرونا حفاظاً عل الزوار من انتقال أي عدوي محتمله.
البلدان المتوسطية العربية والشراكة الأورومتوسطية
Authors: العكروت زياد
Published: May 2022

الشراكة الأورومتوسطية تمثل إحدى المشاريع الخارجية التي عرضت على البلدان العربية جنوب المتوسط، ويعد الاتحاد الأوروبي المهندس والمحرك الرئيسي لها بإيعاز من الجمهورية الفرنسية التي مازالت تعتبر هذه المنطقة امتدادًا لها بحكم الإرث والعلاقات التاريخية. لهذا تلقي هذه الورقة الضوء على البلدان المتوسطية العربية والشراكة الأورومتوسطية، من خلال تحليل الجوانب الأساسية التي ركزت عليها هذه الاتفاقية على الصعيد السياسي والأمني، الاقتصادي والمالي والثقافي والاجتماعي من جهة، وأهم التحديات التي شكلت عائقًا أمام نجاح وامتداد مشروعات التعاون المتوسطي من جهة أخرى. وتقدم الورقة أخيرًا الفرص والإمكانيات وكذلك الآفاق المستقبلية لنجاح وتعزيز التعاون، من خلال إيجاد بدائل لعديد المشاريع من أجل تحقيق التنمية والاستقرار على ضفتي المتوسط.
Молдавська Автономна Радянська Соціалістична Республіка у складі УРСР 1924-1940 рр.: історіографія
Authors: Тучинський Віталій , Левченко Богдан
Published: May 2022

The article aims to study and characterize the scientific works of domestic and foreign historians dedicated to the Moldavian Autonomous Soviet Socialist Republic - a nation-state entity that existed as part of the Ukrainian Soviet Socialist Republic during 1924-1940. The research methodology is based on the general research principles of historicism, objectivity, scientificity, and special historical methods of historiographical, logical, and source analysis, as well as narrative and problem-chronological. The scientific novelty of the work is that it conducted a comprehensive study of the scientific achievements of Ukrainian and Moldovan scientists’ problems related to the formation, features of socio-economic and ethno-national development, as well as the liquidation of the Autonomous Republic of Moldova. Conclusions. The historiography of the chosen problem can be divided into several main periods. The first of them is the work of Soviet researchers. Based on the methodological principles they used, it can be noted that the subject of their research was the historical preconditions for the formation of the Republic and its success in socialist construction. Considerable attention in their works is paid to national and cultural construction, development of education, and culture. The second period covers the works of modern Ukrainian scientists. In the early 1990s, favourable conditions were created for an objective study of the previously unknown and hidden pages of the history of MASSR. This applies primarily to the study of the real reasons for its creation, ethnic composition, mass repressions of the interwar period, as well as foreign policy preconditions for the liquidation of the Autonomous Republic in 1940. The third stage includes the scientific work of historians of Moldova. Its characteristic feature is the study of state-building processes that took place in the Republic and their impact on the formation of the national consciousness of the Moldovan population. To the fourth, we tend to include the works of researchers of the Pridnestrovian Moldavian Republic. They actively study the local lore problems of the history of MASSR and the history of individual settlements in the region. The methodological principles they use give grounds to consider them part of pro-Russian and openly anti-Moldovan historiography.
Суспільно-політична діяльність Михайла Грушевського дореволюційної доби в рецепції української закордонної історіографії (1940-1965 рр.)
Authors: Сабінський Михайло
Published: May 2022

The purpose of the article is to find out the peculiarities of the reception of the pre-revolutionary period of socio-political activity of M. Hrushevsky in Ukrainian foreign historiography (1940s - first half of the 1960s). Historical methods of historiographical research. The scientific novelty of the article is in the attempt to comprehensively reconstruct historiographical discussions around the socio-political activities of M. Hrushevsky of the pre-revolutionary period among Ukrainian foreign historians (1940s - first half of the 1960s.) Conclusions. Ukrainian foreign historiography of the 1940s and the first half of the 1960s was very interested in the pre-revolutionary period of M. Hrushevsky's socio-political activity. At the same time, the assessments of his public initiatives mainly were complementary. They were based on the understanding of the conciliar imperative of all the author's work of the History of Ukraine-Russia. In their reconstructions of the scientist's biography, diasporic Ukrainian studies were usually not original and focused mainly on the historiographical tradition of the previous period. At the same time, memoirs of contemporaries of M. Hrushevsky, who was lucky enough to be on the other side of the "Iron Curtain", brought a lot of new facts and new interpretive models. Also, the general progress of the Ukrainian humanities in the free world suggested a contemporary rethinking of classical Hrushevsky studies. For example, thanks to this, a completely original view of Hrushevsky's public journalism was formed. In general, Hrushevsky's research of the twenty-fifth year enabled the emergence of a new interdisciplinary branch about the Great Ukrainian.
Уманщина під владою гетьмана Павла Скоропадського
Authors: Дудник Олена
Published: May 2022

The article aims to objectively reproduce the picture of the difficult period of socio-political changes that took place throughout the entire period of the existence of the Ukrainian state using archival materials and periodicals on the example of the Uman district of Kyiv province. The research methodology is based on a logical method, which made it possible to combine and generalize already identified historical facts and determine regional features; the principle of historicism in the unity of all components, namely consistency and scientific nature. The scientific novelty of the work is based on the study of the region’s role in the national events in the era of Pavlo Skoropadsky’s rule. This regional direction is significant from a historical point of view. The article is part of a broader study of socio-political, socio-economic and national-cultural events of the Ukrainian revolution of 1917-1921 in the Uman district. Conclusions. The official apparatus changed on the territory of the Uman district during Pavlo Skoropadsky’s rule (April – December 1918). Self-government bodies were subject to audit and prepared for re-elections, which were to be held in November – December 1918. The presence of German troops on the district's territory harmed the process of state creation. Repressions by the authorities, robberies, requisition and confiscation of food, indemnities, coercive measures against peasants, and a complex food situation had resulted in conflicts between the population and the authorities. The policy aimed to provide practical assistance to landlords and breeders in returning lost property measures to prevent anti-Hetman agitation and punish political opponents who did not receive proper support from the majority of the Uman districtpopulation.
Вторинне використання відходів у ранньому Радянському Союзі: історія успіху АТ «Укрутілзбір»
Authors: Перга Тетяна
Published: May 2022

Purpose of the article. A significant number of studies have been devoted to waste disposal in the USSR during the Cold War period when waste transformed into a valuable resource for the demanded products in the postwar USSR. The article examines the earlier period of these activities – the 1920s. Using the example of the Ukrainian USSR, it argues that waste collection and reuse programs have already started in the early Soviet Union. The article demonstrates the activities of the non-state company Ukrutilzbir JSC, which was one of the largest waste procurers on the Republican waste market. The methodological basis. The research is based on the analysis of archival materials that have never been introduced into scientific circulation. Relevance. At the moment, this topic has not been studied at all. Conclusions. The article reveals the success story of this actor, the peculiarity of its activity, balancing dependence and independence from the State, competition with state companies. The article suggests that several factors contributed to the success of the company: the presence of a large quantity of waste in Ukraine, the demand of state enterprises in additional row materials, fairly efficient management, and use of an administrative resource in the form of a monopoly right to collect waste that, however, did not protect the company from problems. The author determined problems encountered by waste pickers due to the poverty of the population, which could not «produce» needed by Soviet enterprises the quantity of waste. The author identified methods of motivating the population to hand over waste. The main actors of the waste market in Ukraine, sources of purchase and sale of waste have been identified. They are the following: enterprises of state industry, state trade, cooperatives, private persons, procurers of waste. The author also had analyzed the attempts of state authorities to regulate the relationship between the main waste producers in Ukraine, that were both partners and competitors.
З історії відбудови та роботи Вінницької залізниці (1943 – 1950)
Authors: Мазило Ігор
Published: May 2022

he purpose of the article is to analyze and characterize the reconstruction of railway transport in the Vinnytsia and Podillia regions, at different stages. Methods of managing the process of transport reconstruction and adjustment of its working are also revealed. The research methodology is based on the application of the principles of objectivity, historicism and systematization using methods of analysis, synthesis and generalization. Scientific novelty lies in the introduction into scientific circulation of a number of new facts and an attempt is made to comprehensively consider the history of the reconstruction of the Vinnytsia railway as a separate business entity. Conclusions. The problems of research of national history from this point of viewallows to understand more clearly the military, economic and social history of the region in the crisis and dramatic years of the war and the postwar period. Reconstruction of the highway took place in several stages. During the war, when the main railways, human-made structures, communication lines, some large nodes and even railway stations were put into operation, there was a significant shortage of specialists, equipment and materials. Therefore, we achieved production results through exhausting work and management methods inherent at that time. The post-war period was more favorable for the reconstruction of the railway, especially after the establishment of railway districts and railway branches in 1946, and in May 1947, employees of the Vinnytsia Railway were transferred to normal, non-military mode. Management of production processes was carried out not only administratively but also economically. The measures taken have paid off. In 1949, the economic activity of the railway became profitable. According to the facts, the social sphere began to be rebuilt immediately after the end of the war, although difficulties with housing and food security took place throughout the reconstruction period.
Архівні джерела про підтримку Січневого повстання 1863 -1864 рр. мешканцями Херсонської губернії Російської імперії та наслідки цих подій для визвольного руху
Authors: Сінкевич Євген
Published: May 2022

The aim of the article is to shed light on the influence of the January Uprising of 1863-1864 on ethnic Polish territory on the revival of the revolutionary and national liberation movement in the Kherson region. The research methodology is based on the principles of objectivity, historicism, systematics, analytical and synthetic critique of sources. The method of historical reconstruction helped to compile from the scattered facts a holistic view of the history of the liberation struggle of the Ukrainian and Polish peoples against tsarism. Scientific novelty is an attempt to systematize our knowledge of the situation in the Kherson region during and after the suppression of the January Uprising of 1863-1864. The main provisions of the article. From the first days of its existence, Kherson, Mykolayiv, Ochakiv, and Odessa had a multinational character due to the tsarist resettlement policy. The national and religious diversity of the region required meeting the urgent needs of the inhabitants. In 1849, Kherson became the center of the Catholic Diocese, which coveredthe southern European part of the Russian Empire. Throughout the nineteenth century, the national liberation struggle and the defense of their own national interests became the content of the Polishsocio-political movement, a powerful impetus for the protection of national culture, language, traditions and religion. The January Uprising, becoming the most massive of all Polish national liberation uprisings, contributed to the growth of national consciousness among a wider section of the Polish community. Conclusions. According to the author, the January Uprising of 1863-1864 had enough sympathizers in the Kherson province, because unlike the situation in Galicia, the Ukrainian and Polish cultural and educational movements were not competitors in the struggle for their own statehood. Despite the persecution and persecution that intensified after the defeat of the January Uprising, national movements continued to unfold in the following decades. At various stages, the Polish community was in search of new, including non-violent, ways to fight for the restoration of lost statehood. In recent decades, Ukrainian scholars have not paid much attention to the impact of the January Uprising on the southern region of Ukraine.
Другий Зимовий похід Армії УНР: сучасна вітчизняна історіографія
Authors: Стопчак Микола
Published: May 2022

The article focuses on a comprehensive analysis of the historiographical work of modern Ukrainian historians on the history of the Second Winter Campaign of the Army of the Ukrainian People Republic in 1921. The methodological basis of the study covers the principles of historicism, objectivity and systematics. General scientific and special research methods were used in solving the set tasks: historiographical analysis and synthesis of knowledge development, generalization, quantitative, historical-comparative, chronological, retrospective, etc. The scientific novelty of the work lies in a comprehensive analysis of the state of study in current national historiography of the history of the Second Winter Campaign of the UPR Army in 1921, clarifies the conceptual approaches and techniques used by modern national experts. Conclusions. The analysis of the historiographical achievements of current Ukrainian historians has shown that they have done a lot to study the research topic. Having brought into scientific circulation previously closed archival materials, both national and foreign, in close cooperation with foreign colleagues, scholars of independent Ukraine rejected the unscientific, politically biased conclusions of Soviet historiography about the Second Winter Campaign directed by the foreign imperialist to overthrow the workers 'and peasants' power in Ukraine, to return it to the hands of the bourgeoisie and the landlords. Certain shortcomings of Ukrainian foreign historiography on this issue have been eliminated, including inaccuracies, a weak source base, and a noticeable memoir in covering many episodes of this  campaign. National experts have clearly proved that the Second Winter Campaign was a heroic attempt of the UPR Army interned in Polish and Romanian camps together with the insurgent Ukrainian people to restore independent Ukrainian statehood. It is shown that the Civil Administration of the Partisan-Insurgent Headquarters carried out serious organizational work aimed at preparing for the restoration of UPR power, but a number of objective and subjective factors led to the defeat of the raid, which negatively affected the further national liberation struggle of the Ukrainian people. At the same time, the historiographical analysis showed that despite the considerable achievements of national historians in studying this topic, not all its aspects were comprehensively covered. A number of them require further scientific analysis and interpretation, which requires significant expansion and updating of the source base.
Protective Effects of Coenzyme Q10 Along with Fe2O3 Nanoparticles On Sperm Parameters in Rats with Scrotal Hyperthermia
Authors: Hashemi Mehrdad , Deldar Abad Paskeh Mahshid , Babaei Nahid , Entezari Maliheh , Doosti Abbas
Published: May 2022

Background: One of the most important factors in reducing the birth rate is male infertility, and one of the main reasons for male infertility is scrotal hyperthermia (SH). Therefore, this study aimed to investigate the protective effect of coenzyme Q10 (CoQ10) along with Fe2O3 nanoparticles on semen parameters in rats with SH. Materials and Methods: Forty-eight adult male Wistar rats were divided into eight groups: healthy control, control group receiving Fe2O3 nanoparticles, control group receiving CoQ10, control group receiving Fe2O3 nanoparticles plus CoQ10, SH group, SH group receiving CoQ10, SH group receiving Fe2O3 nanoparticle, and SH group receiving Fe2O3 nanoparticles plus CoQ10. After killing rats, semen was collected from epididymal tissue, and parameters such as sperm viability, motility, concentration, and morphology were studied. Results: SH significantly reduced sperm concentration, motility, and viability, as well as altering sperm morphology in rats. Nevertheless, CoQ10 strongly improved sperm parameters in SH rats. Fe2O3 nanoparticles led to a sharp decrease in sperm parameters; however, during the simultaneous administration of Fe2O3 nanoparticles with CoQ10, improvement in sperm parameters was seen in the SH rats. Conclusion: Our findings suggest that CoQ10, along with Fe2O3 nanoparticles, has a protective effect against spermatogenic cell death induced by SH. Thus, green synthesis of nanoparticles with the administration of antioxidants, including CoQ10 is recommended for the treatment of SH. [GMJ.2022;11:e2046]
Methods of Finite Differences in the Domain of Time Applied to the Equation of Heat Biotransfer in Ocular Tissues
Authors: Souza Samuel Ferreira de , Carvalho Júnior Carlos Alberto Tenório de , Montero Ciro José Egoavil , Barrozo da Silva Viviane , Ricciotti Antonio Carlos Duarte , Pequeno Petrus Luiz de Luna , Sampaio Daniela de Araújo , Lima Jorge Luis Nepomuceno de
Published: May 2022

This article presents a methodology for two-dimensional modeling of the human eye to analyze the heat transfer in biological tissues, in this case, ocular tissues. The technique used was the finite differences method in the time domain. With a proposal for a numerical simulation of the problem, see that this type of work aims to promote the development of tools that help detect errors in biomedical engineering. Several medical procedures, including surgical ones that use laser, whose main limiting factor is the increase in temperature in living tissue, a fact that can cause irreversible damage, even evaporating. For example, refractive eye surgery using a laser. The simulation is intended to calculate the temperature gradient to guide the physician more precisely before an intervention. An example of this is certain types of inoperable tumors that can be irradiated with laser sources. Their function is to cause a rise in local temperature to destroy cancer cells without thermal damage to the healthy region.
Екологічні особливості сучасного стану деревно-чагарникових видів рослин у садах і парках колишніх залізних рудників Криворіжжя
Authors: Савосько Василь Миколайович
Published: May 2022

За показниками флористичного складу, біоморфічного, екоморфічного та біогеографічного спектрів наведено показники сучасного стану дерев та чагарників у садах і парках колишніх залізних рудників Криворіжжя. В обстежених восьми діючих парках, трьох занедбаних об’єктах озеленення поруч із зоною відчуження та в одному саду виявлено 97 видів дерев і чагарників із 56 родів і 27 родин. Серед них 17 видів, 8 родів і 4 родини з відділу Pinophyta, а також 80 видів, 48 родів і 23 родини з відділу Magnoliophyta. Серед них найбільш представлені родини Rosaceae (18 видів), Salicaceaе (9 видів), Oleaceae (7 видів), Aceraceae (7 видів). Трохи менш численними є родини Fabaceae (5 видів), а також Caprifoliaceae, Hydrangeaceae та Ulmaceae (по 4 види). Серед біоморф за кількістю видів дерева (68 %) переважають над чагарниками (32 %). Серед трофоморф домінують мезотрофи (34 %), середню кількість мають мегатрофи (25,8 %) та олігомезотрофи (21,6 %). Серед гігроморф домінують мезофіти (33,0 %), мезогігрофіти (28,9 %) та ксеромезофіти (24,7 %). Серед геліоморф домінують геліофіти (61,9 %) та сціогеліофіти (26,8 %). За кількістю видів дерев і чагарників інтродуценти (65 %) переважають над аборигенами (34 %). Ці види природно поширені у Бореальному, Давньосередземноморському, Мадреанському підцарствах Голарктичного царства. Циркумбореальна, Східноазійська, Атлантико-Північноамериканська й Ірано-Туранська області характеризуються найбільшою кількістю видів дерев і чагарників. Результати кореляційних розрахунків підтвердили, що між показниками сучасного стану дерев, чагарників та характеристиками територій садів і парків колишніх залізних рудників Криворіжжя є достовірний зв’язок. Серед екологічних характеристик територій найістотніший вплив на поширення дерев і чагарників мають показники забруднення атмосферного повітря та площа територій.
Апофітні та адвентивні деревні види на девастованих землях гранітних кар’єрів Криворіжжя
Authors: Савосько Василь Миколайович , Лихолат Юрій Васильович , Бєлик Юлія Вільєвна , Григорюк Іван Панасович
Published: May 2022

Показано, що вивчення закономірностей самозаростання і синантропних характеристик деревних видів рослин й чагарників на девастованих землях гранітних кар’єрів Криворіжжя є важливою передумовою фітооптимізації навколишнього природного середовища в індустріально розвинених регіонах України. Мета дослідження – з позицій еко-системного підходу з’ясувати видовий склад, структуру апофітної й адвентивної фракцій деревних й чагарникових видів рослин на девастованих землях гранітних кар’єрів Криворіжжя. Матеріалами роботи слугували результати власних польових досліджень, які виконували упродовж 2017-2018 рр. на території девастованих земель Коломоївського, Жовтневого та Карачунівського гранітних кар'єрів Криворізького залізорудного регіону. Установлено, що в межах названих територій зростає 34 види дерев і чагарників, що належать до 25 родів, 15 родин та відділу Покритонасінні (Magnoliophyta). Провідними родинами визнано: розові, маслинові, вербові, кленові та в’язові. Ці види дерев і чагарників, як синантропні рослини, поділяють на апофітну (автохтонні види) та антропофітну, або адвентивну (автохтонні види) фракції. Серед апофітних видів переважають геміапофіти, а з антропофітних за часом занесення – неофіти, способом інвазії – ергазіофіти, ступенем адаптації – ергазіофіти та епекофіти. Визначено, що серед видів рослин на девастованих землях інвазійно найактивнішими і небезпечними для природних екосистем регіону виявились айлант найвищий (Ailanthus altissima (Mill.)), клен ясенолистий (Acer negundo L.), маслинка вузьколиста (Elaeagnus angustifolia L.) та робінія звичайна (Robinia pseudoacacia L.), використання яких для фіторекультивації потребує додаткової уваги та обережності.
Strategic priorities of innovation and investment development of the Ukraine's economy industrial sector
Authors: Stadnyk Vаlentyna , Izhevskiy Pavlo , Khrushch Nila , Lysenko Sergii , Sokoliuk Galyna , Tomalja Tetjana
Published: May 2022

The problem of determining the investment priorities of the national economy development has been actuated. It has been argued that the formation of institutional preferences for activation of industry investment processes should be carried out taking into account the potential ability of each sectoral group enterprises to increase the added value. The scientific and methodical approach for sub-sectors investment attractiveness assessment has been formed on the example of the Ukrainian food industry. It has been recommended to use for this substantiated set of relative performance indexes which are duplicated in aggregate statistical state surveys based on the enterprise’s financial statements. It has been formed the recommendations for the investment priorities of food industry development in Ukraine which are based on the appropriate calculations made by the TOPSIS and CRITIC methods. Methods of economic-statistical and comparative analysis were used for structural and dynamic characteristics of the Ukraine industrial enterprises activities. Given that innovation processes should also cover small and medium-sized industrial enterprises, whose resource opportunities are mostly limited, it is proposed to expand them within the framework of a strategic partnership. Graphic modeling methods have been used to visualize the process of building the business structures resource potential on the basis of their strategic partnership. The influence of the motivational environment on the value of organizational relations within the partnership has been formalized.
The Effect of Tax Incentives, Taxpayer Awareness, Tax Sanctions and Implementation of E-filling on MSME Taxpayer Compliance
Authors:   Politeknik Negeri Bali, Sari Putu Indrika , Pradnyani N L P Norma Dewi Abdi ,   Politeknik Negeri Bali, Suprapto P Adi ,   Politeknik Negeri Bali
Published: May 2022

This study aims to determine the effect of tax incentives, taxpayer awareness, tax sanctions, and the application of e-filling on MSME taxpayer compliance at the Gianyar Pratama Tax Service Office. This study is a quantitative study using primary data obtained from the answers to questionnaires distributed to respondents and measured using a likert scale. Determination of the sample in this study using incidental sampling technique and obtained a total sample of 100 MSME taxpayers registered at the KPP Pratama Gianyar. Testing the variables in this study using the Partial Least Square (PLS) method using the SmartPLS 3.0 application. The results of the study indicate that tax incentives, taxpayer awareness, tax sanctions, and the implementation of e-filling have a positive and significant impact on MSME taxpayer compliance. Further research is expected to be able to add or use other variables besides the variables used in this study so that further research is better.