bluuebunny/crossref_metadata_2025 huggingface dataset:
Seroprevalence of Measles Antibodies in the Population of the Olomouc Region, Czech Republic—Comparison of the Results of Four Laboratories
Authors: Krupka Michal , Matusu Tereza , Sutova Helena , Wezdenkova Katerina , Vecerova Renata , Smesna Yvona , Kolar Milan , Frankova Hana Bilkova , Krivankova Jana , Jorenek Miroslav , Novak Zdenek , Raska Milan , Holy Ondrej
Published: January 2022

Objectives: Although the incidence of measles has decreased globally since the introduction of regular vaccination, its frequency has increased again in recent years. The study is focused on data from the Olomouc Region in the Czech Republic analyzed in four laboratories. The obtained results were compared with already published data. Methods: The data were provided by individual laboratories in an anonymized form—age at the time of the examination, sex, and result of test. Samples were collected between June 2018 and September 2019 and evaluated on the scale positive–borderline–negative. Results: A total of 7962 sera samples were evaluated using three different methods—two types of ELISA tests and CLIA. Positive result was issued in a total of 62.6 percent of samples, but the results of individual laboratories varied widely from 55.5 to 70.8 percent. However, the same trend with the highest levels of antibodies in people born before beginning of vaccination was observed. Conclusions: Data show significantly different results depending on the individual laboratories and the detection kits used. The underestimation of the proportion of positive results can cause problems in selecting individuals for revaccination with a live vaccine, which may fail in weakly positive individuals.
Designing a Recombinant Vaccine against Providencia rettgeri Using Immunoinformatics Approach
Authors: Gul Saba , Ahmad Sajjad , Ullah Asad , Ismail Saba , Khurram Muhammad , Tahir ul Qamar Muhammad , Hakami Abdulrahim R. , Alkhathami Ali G. , Alrumaihi Faris , Allemailem Khaled S.
Published: January 2022

Antibiotic resistance (AR) is the resistance mechanism pattern in bacteria that evolves over some time, thus protecting the bacteria against antibiotics. AR is due to bacterial evolution to make itself fit to changing environmental conditions in a quest for survival of the fittest. AR has emerged due to the misuse and overuse of antimicrobial drugs, and few antibiotics are now left to deal with these superbug infections. To combat AR, vaccination is an effective method, used either therapeutically or prophylactically. In the current study, an in silico approach was applied for the design of multi-epitope-based vaccines against Providencia rettgeri, a major cause of traveler’s diarrhea. A total of six proteins: fimbrial protein, flagellar hook protein (FlgE), flagellar basal body L-ring protein (FlgH), flagellar hook-basal body complex protein (FliE), flagellar basal body P-ring formation protein (FlgA), and Gram-negative pili assembly chaperone domain proteins, were considered as vaccine targets and were utilized for B- and T-cell epitope prediction. The predicted epitopes were assessed for allergenicity, antigenicity, virulence, toxicity, and solubility. Moreover, filtered epitopes were utilized in multi-epitope vaccine construction. The predicted epitopes were joined with each other through specific GPGPG linkers and were joined with cholera toxin B subunit adjuvant via another EAAAK linker in order to enhance the efficacy of the designed vaccine. Docking studies of the designed vaccine construct were performed with MHC-I (PDB ID: 1I1Y), MHC-II (1KG0), and TLR-4 (4G8A). Findings of the docking study were validated through molecular dynamic simulations, which confirmed that the designed vaccine showed strong interactions with the immune receptors, and that the epitopes were exposed to the host immune system for proper recognition and processing. Additionally, binding free energies were estimated, which highlighted both electrostatic energy and van der Waals forces to make the complexes stable. Briefly, findings of the current study are promising and may help experimental vaccinologists to formulate a novel multi-epitope vaccine against P. rettgeri.
Comparing SARS-CoV-2 Antibody Responses after Various COVID-19 Vaccinations in Healthcare Workers
Authors: Kim Yu-Kyung , Minn Dohsik , Chang Soon-Hee , Suh Jang-Soo
Published: January 2022

Coronavirus disease 2019 (COVID-19) vaccination began for healthcare workers in South Korea at the end of February 2021. This study investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody responses after various COVID-19 vaccinations in healthcare workers. Blood specimens of 497 vaccinated healthcare workers were collected. Inoculated vaccines were ChAdOx1 (AstraZeneca/Oxford), BNT162b2 (Pfizer/BioNTech), JNJ-78436735 (Janssen), and mRNA-1273 (Moderna). Each specimen was tested for antibodies against SARS-CoV-2 using Elecsys Anti-SARS-CoV-2 S assay (Roche Diagnostics), SARS-CoV-2 IgG II Quant assay (Abbott), and R-FIND SARS-CoV-2 Neutralizing Antibody kit (SG medical Inc.). A questionnaire was used to investigate adverse events related to vaccination. We found that 99.5% of the subjects showed a 96–100% positive rate in all three antibody assays, regardless of the vaccine type. The antibody-positive rate of completed vaccination groups reached 96–100%, and antibody quantities significantly increased 2 weeks after vaccination. The antibody values measured approximately 3 months after BNT162b2 inoculation significantly correlated with adverse events.
Acknowledgment to Reviewers of Vision in 2021
Authors:   Vision Editorial Office
Published: January 2022

Rigorous peer-reviews are the basis of high-quality academic publishing [...]
Spatiotemporal Characteristics Analysis and Driving Forces Assessment of Flash Floods in Altay
Authors: Ahemaitihali Abudumanan , Dong Zuoji
Published: January 2022

Flash floods are devastating natural disasters worldwide. Understanding their spatiotemporal distributions and driving factors is essential for identifying high risk areas and predicting hydrological conditions. In this study, several methods were used to analyze the changing patterns and driving factors of flash floods in the Altay region. Results indicate that the number of flash floods each year increased in 1980–2015, with two sudden change points (1996 and 2008), and April, June, and July presented the highest frequency of events. Habahe and Jeminay were known to have high flash flood incidences; however, currently, Altay City, Fuhai, Fuyun, and Qinghe are most affected. In terms of driving force analysis, precipitation and altitude performance have a key impact on flash flood occurrence in this settlement compared to other subregions, with a high percentage increase in the mean squared error value of 39, 37, 37, 37, and 33 for 10 min precipitation in a 20-year return period, elevation, 60 min precipitation in a 20-year return period, 6 h precipitation in a 20-year return period, and 24 h precipitation in a 20-year return period, respectively. The study results provide insights into spatial–temporal dynamics of flash floods and a scientific basis for policymakers to set improvement targets in specific areas.
Spatial Variability of the Mechanical Parameters of High-Water-Content Soil Based on a Dual-Bridge CPT Test
Authors: Lu Haifeng , Li Huiying , Meng Xiangshuai
Published: January 2022

Soft soil generally has a high water content, and the accurate quantification of its mechanical parameters is an important aspect of foundation design and disaster prevention. The mechanical parameters of soft soil have significant spatial variability or heterogeneity due to the complex deposition process of soil, leading to the high uncertainty of the quantifications of its parameters. Therefore, understanding the spatial variability of the parameters is an important approach to reduce uncertainty. In this study, the high-resolution (0.1 m) tip resistance (qc) and side friction (fs) of 18 soft soils in coastal areas were measured using the Dual-bridge CPT in-situ test. The vertical and horizontal variabilities of qc and fs were investigated using the random field theory. The results showed that both qc and fs are stationary and ergodic. The coefficient of variation of vertical fs is much higher than that of qc. On the one hand, fs may be vulnerable to noise, and its test accuracy is lower than qc; on the other hand, it may be that the spatial variability of the residual strength of soft soil may be greater than that of its failure strength. The horizontal correlation distance and coefficient of variation of qc and fs have no obvious change trend along the depth direction, but compared with the coefficient of variation curve, it was found that the change trends of qc and fs are basically the same, which is considered to be related to the properties of the soil layer. The research results can provide support for the spatial variability evaluation and reliability analysis of soft-soil engineering in this area. At the same time, it can also provide a theoretical basis for the layout of exploration engineering and sampling spacing.
Applications of Computational and Statistical Models for Optimizing the Electrochemical Removal of Cephalexin Antibiotic from Water
Authors: Arab Maliheh , Faramarz Mahdieh Ghiyasi , Hashim Khalid
Published: January 2022

One of the most serious effects of micropollutants in the environment is biological magnification, which causes adverse effects on humans and the ecosystem. Among all of the micro-pollutants, antibiotics are commonly present in the aquatic environment due to their wide use in treating or preventing various diseases and infections for humans, plants, and animals. Therefore, an aluminum-based electrocoagulation unit has been used in this study to remove cephalexin antibiotics, as a model of the antibiotics, from water. Computational and statistical models were used to optimize the effects of key parameters on the electrochemical removal of cephalexin, including the initial cephalexin concentration (15–55 mg/L), initial pH (3–11), electrolysis time (20–40 min), and electrode type (insulated and non-insulated). The response surface methodology-central composite design (RSM-CCD) was used to investigate the dependency of the studied variables, while the artificial neural network (ANN) and adaptive neuro-fuzzy inference system (ANFIS) methods were applied for predicting the experimental training data. The results showed that the best experimental and predicted removals of cephalexin (CEX) were 88.21% and 93.87%, respectively, which were obtained at a pH of 6.14 and electrolysis time of 34.26 min. The results also showed that the ANFIS model predicts and interprets the experimental results better than the ANN and RSM-CCD models. Sensitivity analysis using the Garson method showed the comparative significance of the variables as follows: pH (30%) > electrode type (27%) > initial CEX concentration (24%) > electrolysis time (19%).
Evaluation of the Light/Dark Cycle and Concentration of Tannery Wastewater in the Production of Biomass and Metabolites of Industrial Interest from Microalgae and Cyanobacteria
Authors: Urbina-Suarez Néstor A. , Ayala-González Darly D. , Rivera-Amaya Jennyfer D. , Barajas-Solano Andrés F. , Machuca-Martínez Fiderman
Published: January 2022

The tanning industry transforms animal skins into leather and produces liquid effluents with a high organic and inorganic pollutant load. This work evaluated the effect of the tannery wastewater (TWW) concentration and the light/dark cycle on the production of biomass, carbohydrates, proteins, lipids, and pigments (carotenoids and phycobiliproteins) on two microalgae (Chlorella sp. and Scenedesmus sp.) and one cyanobacterium (Hapalosiphon sp.). A non-factorial central experimental design with a response surface was implemented using the STATISTICA 7.0 software. High removal percentages for nitrates (97%), phosphates (73.3%), and chemical oxygen demand (93.2%) were achieved with the three strains. The results also highlight that the use of a constant light regime (24:0) and the concentration of real TWW affect the biomass production, since the highest concentration of biomass recorded was 1.31 g L−1 of Hapalosiphon sp. with 100% undiluted wastewater.
Changes in the Heat Content of Water Column in the Slope Area of the Southern Basin of Lake Baikal in the 21st Century
Authors: Troitskaya Elena , Budnev Nikolay , Shimaraev Mikhail
Published: January 2022

Climate change influences the temperature, ice and thermal regimes of lakes in the Northern Hemisphere. This study discusses the change in the heat content of the water column in the slope area of the southern basin of Lake Baikal under the influence of climate for the past 20 years. We clarify the seasonal variability of heat content in different water layers selected taking into account temperature and dynamic characteristics. During the study period, the value of heat content increased in the upper water layer (45–100 m) only in May (12.4 (MJ/m2)/year). In the water layers deeper than 100 m, the value of heat content decreased: −3–−4 (MJ/m2)/year from July to September in a layer of 100–300 m, −9–−13 (MJ/m2)/year in all months in a layer of 300–1100 m and −1.5–−3 (MJ/m2)/year in all months, except for January in a layer of 1100 m–bottom. Despite the revealed trends of the change in the heat content, the annual heat circulation remained within the normal range and did not have any trends.
Simplified Modelling of Coupled Surface-Groundwater Transport Using a Subcatchment Mass Balance Approach
Authors: Elliott Alexander Hewgill , Rajanayaka Channa , Yang Jing
Published: January 2022

Catchment models based on steady-state mass balances enable rapid assessment of contaminant fluxes and concentrations in rivers. However, such models often focus on surface drainage, without taking groundwater into account. This paper presents a novel steady-state mass-balance catchment model that includes groundwater. The model incorporates a conceptual reservoir under each surface subcatchment, with lateral subsurface exchanges between adjacent reservoirs and vertical exchanges between the reservoirs and the surface drainage network. This leads to an easily solved coupled algebraic system of equations. The approach is demonstrated for nitrogen in a meso-scale catchment in New Zealand. Exchange coefficients were extracted from a full groundwater model, while recharge sources were obtained from separate hydrological and leaching models. Other parameters such as decay coefficients were determined through calibration. Although the exchange coefficients are generated from a detailed groundwater model, alternatives such as simple groundwater models or phreatic contours could be used instead. The effective decay parameters were different from what was expected, which is partly due to the model structure (for example, the assumption of complete mixing in each reservoir), but may also be due to input uncertainty. The applications demonstrated the successful deployment of a novel, simple, fast-running and flexible coupled surface-groundwater model.
Relationships as a Basis for Safe Drinking Water Provision by Cooperatives in Rural Chile
Authors: Pareja Pineda Claudio , Fuentes Norka , Arriagada Aldo
Published: January 2022

While access to drinking water has expanded worldwide, safely managed provision is still a challenge, and rural areas are specially underserved. To provide safe drinking water for these areas, water scholars and international organizations have advocated for community-based organizations or coproduction schemes. The literature often mentions that institutions and people play a key role in the provision of drinking water although the specific mechanisms through which they may affect the process of maintaining good quality water have not been reported yet. The article aims to fill this gap by providing a complex, local view on this process. In Chile, from 1960 onwards, the State has implemented cooperatives to provide for drinking water in rural and small-town areas under a coproduction scheme. In this scheme, the State provides the infrastructure, and the community is responsible for service provision. We analysed the water quality of six of these cooperatives and conducted interviews with water managers and leaders. Our research suggests that formal and informal relationships provide the links and motivation needed for the organizations continuous work. These results highlight how relevant it is to keep in mind the context and the public role of delivering safe drinking water.
Special Issue “The Response of the Plankton Community to Environmental Stress”
Authors: Korponai János , Selmeczy Géza
Published: January 2022

The equilibrium of ecosystems highly depends on its health (resilience) and the strength and intensity of environmental influences [...]
Taxonomic and Functional Responses of Species-Poor Riverine Fish Assemblages to the Interplay of Human-Induced Stressors
Authors: Colin Nicole , Habit Evelyn , Manosalva Aliro , Maceda-Veiga Alberto , Górski Konrad
Published: January 2022

The effects of human-induced stressors on riverine fish assemblages are still poorly understood, especially in species-poor assemblages such as those of temperate South American rivers. In this study we evaluated the effects of human-induced stressors on the taxonomic and functional facets of fish assemblages of two central-southern Chilean rivers: the Biobío River (flow regulated by multiple dams) and the Valdivia River (free-flowing). The study design considered reference condition, urban polluted, and urban-industrial polluted sites. To evaluate the effects of stressors on fish assemblages we assessed: (i) components of beta diversity; (ii) spatial and temporal patterns of fish structure using a multivariate approach; and (iii) functional diversity (specialization, originality, dispersion, and entropy) using linear models. We found a strong association between taxonomic and functional fish assemblage facets with a predominance of natural processes in the Valdivia River reflected in marked temporal dynamics. In contrast, the Biobío River showed a clear loss of association with seasonal pattern, and both taxonomic and functional facets appeared to respond significantly to pollution zones. Implementation of stricter environmental policies and integrated river basin management are instrumental for conserving species-poor fish assemblages in Chilean temperate rivers characterized by low functional traits redundancy.
The Taiwan Climate Change Projection Information and Adaptation Knowledge Platform: A Decade of Climate Research
Authors: Lin Lee-Yaw , Lin Cheng-Ting , Chen Yung-Ming , Cheng Chao-Tzuen , Li Hsin-Chi , Chen Wei-Bo
Published: January 2022

Taiwan’s climate change projections have always presented a challenge due to Taiwan’s size and unique meteorological and geographical characteristics. The Taiwan Climate Change Projection Information and Adaptation Knowledge Platform (TCCIP), funded by the Ministry of Science and Technology, Taiwan, is a decade-long climate research project with the most predominant climate data provider and national adaptation policymaking in the country. This paper outlines the evolution of the project. It describes the project’s major achievements, including climate projection arising from participation in the WCRP Coupled Model Inter-comparison Project (CMIP), dynamically and statistically downscaled data with resolutions up to 5 km grid, impact assessments of various themes, such as flooding, as well as the support of national policies through approaches including risk maps, climate data, and knowledge brokering.
Supporting a Resilience Observatory to Climate Risks in French Polynesia: From Valorization of Preexisting Data to Low-Cost Data Acquisition
Authors: Jessin Jérémy , Heinzlef Charlotte , Long Nathalie , Serre Damien
Published: January 2022

Climate change has an ever-increasing impact on island territories. Whether it is due to rising sea levels or the increase in recurrence and intensity of extreme events, island territories are increasingly vulnerable. These impacts are expected to affect marine and terrestrial biodiversity, human occupation (infrastructure) and other activities such as agriculture and tourism, the two economic pillars of French Polynesia. While the current and future impacts of climate change on island territories are generally accepted, data acquisition, modeling, and projections of climate change are more complex to obtain and limitedly cover the island territories of the Pacific region. This article aims to develop methodologies for the acquisition and exploitation of data on current and future climate risks and their impacts in French Polynesia. This work of acquisition and valorization is part of a research project for the development of an observatory of resilience to climate risks in the perspective of building a spatial decision support system.
Acknowledgment to Reviewers of Women in 2021
Authors:   Women Editorial Office
Published: January 2022

Rigorous peer-reviews are the basis of high-quality academic publishing [...]
Analysis of the efficiency of the provision of services of the city club space «My Social Center» in Moscow
Authors:   Faculty of Social Work, Russian State Social University, Karpunina Anastasiya Vladimirovna , Kramareva Anastasiya Olegovna ,   Faculty of Social Work, Russian State Social University
Published: January 2022

The tasks of modern social work with the elderly are related to their social adaptation and inclusion, the preservation and extension of their social activity, and the development of their personal potential, primarily to meet a variety of cultural and educational needs, needs for communication and recognition, as well as the awakening of new interests, facilitating the establishment of friendly contacts, the activation of personal activity of the elderly, the formation, support and improvement of their vitality. The introduction of innovative forms of social work is highly relevant in this context. One of such complex forms is the project "My Social Center", launched in Moscow in 2019.
Modern approaches to the development of individual independence in the age of globalization
Authors:   Private school ", Khalikova Dzheni Andreevna ,   Vzmakh",   ,  St. Petersburg
Published: January 2022

The article analyzes the concept of the development of "independence" of the individual within the framework of changes in the educational environment. The author considers the specifics of the pedagogical features of the development of individual independence. The levels of development of independence in children of middle preschool age are identified. The analysis of the works of K.A. Abulkhanova-Slavskaya, L.S. Vygotsky, A.V. Zaporozhets, A.N. Leontiev, S.L. Rubinstein, and I.S. Kon allows determining scientific approaches to the problem of the development of independence as an identity of a person. With the help of the personal-activity approach of E.V. Ilyenkov, A.N. Leontiev, S.L. Rubenstein, as well as scientific works devoted to the development of independence in preschoolers by Z.V. Eliseev, N.S. Krivov, A.A. Lyublinskaya, K.P. Kuzovkov, the author was able to organize and conduct an experimental study. This study to determine the level of independence of the individual proves the effectiveness of the selected methods and techniques of working with preschoolers. The research methodology included: theoretical analysis of literary sources, observation, a map of manifestations of independence by A.M. Shchetinina; statistical methods of processing the obtained data. Scientific and theoretical analysis shows that actually independent activity is most fully defined as purposeful, internally motivated by the object itself in the totality of actions performed and corrected by the object according to the process and result of the activity. The pedagogical features of the formation of personality independence are the use of personality-activity and subject approaches. According to the results of the study of the development of independence in children of middle and preschool age in the practice of preschool educational institutions, a conclusion about the average level of the development of independence can be made. The study does not pretend to be complete and can be continued from the point of view of expanding the pedagogical process of development and the formation of individual independence.
Socio-psychological portrait of women who have been subjected to violence: general characteristics of the problem in the Scandinavian countries and Russia
Authors:   FSBEI HE Bashkir State University, Ufa, Bolshakova Nataliya Leonidovna
Published: January 2022

The article provides a comparative analysis of the socio-psychological portrait of women who have been subjected to violence abroad and in Russia. The subject of the analysis is the psychological, social and national characteristics of women who have ever been subjected to violence. The difficulties of adopting the draft law "On the prevention of domestic violence in the Russian Federation" are considered in detail. This draft law gives a broad interpretation of the concept of "domestic violence" and proposes to accept this phenomenon as a legal problem in order to effectively combat domestic violence. It is noted that Scandinavian women differ from each other in their national and psychological characteristics, consequently, when faced with domestic violence, they will also behave completely differently. However, the socio-psychological portrait of the victims, both in Russia and in Northern Europe, will be the same. In this regard, there is an urgent need for theoretical and empirical research in the field of organizing social work with women who have been subjected to violence, where the key element is the provision of a wide range of social services by social work specialists to this category of the population. The social experience of the Northern European countries in providing assistance to female victims of domestic violence is very effective.
Possibilities of using gamification in distance education
Authors:   OBPOU «KTS», Kursk, Kotov Sergey Sergeevich , Kotova Natalya Anatolyevna ,   OBPOU «KTS», Kursk
Published: January 2022

The article discusses the problems of using game mechanisms (Gamification) to increase motivation and attract students participating in distance educational activities. Distance learning has become the dominant form of education at various levels of education during the COVID-19 pandemic. It is highly probable that in the future such courses will also represent a significant and larger than hitherto part of the educational offer of universities and other educational institutions. With the spread and massive introduction of distance learning, the role and importance of teachers has increased, who in a relatively short time had to adjust the materials and content of training to the conditions and opportunities of online education. Maintaining the attention and participation of distance learning participants was a significant challenge and challenge. The aim of the work is to clarify the concept of gamification and discuss the mechanisms of play and their possible use in the context of learning. The effectiveness of gamification has been discussed in the light of selected theories of psychology in relation to the technological possibilities of online education. The article also presents examples of selected applications and platforms that can be useful for creating educational materials and tasks performed in a distance form at the level of professional education.
On the issue of the formation of professional competence of a teacher, taking into account the requirements of Worldskills standards
Authors:   OBPOU «Kursk Technical School of Communications», Kursk, Russia, Gruneva Anna , Nikolenko Denis Vladimirovich ,   OBPOU «Kursk Technical School of Communications», Kursk, Russia
Published: January 2022

WorldSkills Championships set high standards of professional excellence, foster pride in their specialization, make them see the smallest details of problems, and optimize the student's path to a high level of professional activity. During the competition, it becomes possible to assess the level of formation of professional competencies of future graduates, to make suggestions and draw conclusions about the quality of professional and pedagogical training of students. The article presents the current trends in the development of secondary vocational education in the context of the transition to a new digital economy. International movement WorldSkills as a resource for the development of the teaching profession. The prospects and problems of training teachers in accordance with WorldSkills standards are described. Approaches to the assessment of professional pedagogical activity: the place of WorldSkills assessment tools and technology in the implementation of the educational process. The conclusion about the professional readiness of future IT specialists is a complex of personal skills, the development of which is the result of a targeted professional impact by means of specialized resources that allow for effective preparation for successful professional activity.
State regional investment policy: instrumental support
Authors:   Kursk State Agricultural Academy named after I. I. Ivanova, Russia, Ustinovich Elena Stepanovna
Published: January 2022

The problems of investment policy, of all its most important directions, in the opinion of most economists, were and remain relevant, in general, for the Russian Federation and for its regions: the emasculation of the economic essence of investment, the investment recession, i.e. an increase in the number of constituent entities of the Russian Federation with decreasing volumes of investment activity. In the context of modern economic development, the constituent entities of the Russian Federation are assigned an increasing role in increasing the scale and priorities of their investment activities. The formation and implementation of the investment policy of the regions of the Russian Federation is becoming, in general, an important innovative and socially oriented direction of the economic policy of the Russian state. The primary and two-pronged goal of the regional investment policy is to mobilize state investment resources while simultaneously creating favorable and comfortable conditions for enhancing investment activity. It is in the constituent entities of the Russian Federation that projects for the modernization of production potential are being implemented, structural shifts in the region’s economy are being laid and developed, and the necessary economic and social facilities are being created again. The article presents the basic principles of the formation and implementation of the state regional investment policy.
A Novel Predictive Model for Hospital Survival in Patients who are Critically Ill with Dialysis-Dependent AKI: A Retrospective Single-Center Exploratory Study
Authors: Ganguli Anirban , Farooq Saad , Desai Neerja , Adhikari Shreedhar , Shah Vatsal , Sherman Michael J. , Veis Judith H. , Moore Jack
Published: January 2022

Background

Mortality of patients who are critically ill with AKI initiated on RRT is very high. Identifying modifiable and unmodifiable clinical variables at dialysis start that are associated with hospital survival can help, not only in prognostication, but also in clinical triaging.

Methods

A retrospective observational study was conducted on patients with AKI-D who were initiated on RRT in the medical and surgical intensive care units (ICUs) of a high-acuity academic medical center from January 2010 through December 2015. We excluded patients with suspected poisoning, ESKD, stage 5 CKD not on dialysis, or patients with AKI-D initiated on RRT outside of the ICU setting. The primary outcome was in-hospital mortality.

Results

Of the 416 patients who were critically ill with AKI-D admitted to the medical (38%), surgical (41%), and cardiac (21%) ICUs, with nearly 75% on artificial organ support, the mean age 62.1±14.8 years, mean SOFA score was 11.8±4.3, dialysis was initiated using continuous RRT in 261 (63%) and intermittent hemodialysis in 155 (37%) patients. Incidence of survival to hospital discharge was 48%. Using multivariable logistic regression with stepwise backward elimination, a prognostic model was created that included the variables age, CKD, COPD, admission, and within 24 hours of the start SOFA score, refractory hyperkalemia and uremic encephalopathy as dialysis indications, BUN >100 mg/dl, serum creatinine, serum lactate, serum albumin, CRRT as initial modality, severe volume overload, and abdominal surgery. The model exhibited good calibration (goodness of fit test, P=0.83) and excellent discrimination (optimism-corrected C statistic 0.93).

Conclusions

In this single-center, diverse, critically ill AKI-D population, a novel prognostic model that combined widely used ICU scores, clinical and biochemical data at dialysis start, and dialysis indication and modality, robustly predicted short-term survival. External validation is needed to prove the generalizability of the study findings.
Review of research on salt-affected soils in the Debrecen agricultural high educational institutions, with special focus on the mapping of Hortobágy
Authors: Tóth Tibor , Pásztor László , Árvai Mátyás , Sipos György , Takács Katalin , Rékasi Márk , Szatmári Gábor , Balog Kitti , Kovács Zsófia Adrienn
Published: January 2022

The history of the research of Debrecen scholars on salt-affected soils of Hortobágy and the region is very rich and diverse. Focusing on mapping, the following stages can be distinguished, indicating the completeness of the maps and the purpose of the performed work− First, quantitative maps (Arany, 1926) for the utilization of the lands at 1:75,000 (Figure 1).− Second, quantitative map (Kreybig, 1943) for the utilization of the lands at 1:25,000.− Third, category map (Kreybig et al., 1935) testing the suitability of the classification system at  :75,000.− Fourth, partial category map (Szabolcs, 1954), showing the reasons of unsuccessful management at 1:10,000.− Fifth, partial quantitative map (Csillag et al., 1996), showing the utility of digital sampling at 1:25,000.− Sixth, partial quantitative map (Tamás and Lénárt, 2006), showing the capacity of multispectral  remote imagery at 1:100.− Seventh, partial quantitative map (Douaik et al., 2006), showing the usefulness of geostatistical  mapping at 1:10,000.− Eight, national quantitative maps (Pásztor et al., 2016), showing the applicability of geostatistics for administrative purposes at 1:10,000.− Ninth, partial quantitative/category map (authors, 2019), finding the optimal methods at 1:10,000.
Проривні технології в оборонній сфері України
Authors: Слюсар Вадим Іванович , Сотник Владислав Віталійович , Купчин Артем Валерійович , Шостак Владислав Григорович
Published: January 2022

Основним месседжем написання цієї статті є формування наукового зацікавлення на предмет ідентифікації проривних технологій, як суттєвого інструменту зміцнення технологічної безпеки країни.

У роботі описано досвід НАТО щодо визначення переліку проривних технологій. Визначені спільні та відмінні риси критичних та проривних технологій. Обґрунтовано актуальність та необхідність створення одного уніфікованогопереліку критичних і проривних технологій.

Запропоновано дефініцію критичних і проривних технологій в оборонній сфері, а також новий концептуальний підхід щодо їх структурування.

Опрацьовано методику формування переліку критичних і проривних технологій на основі нечіткої логіки. Визначено математично обґрунтовані межі ідентифікації технології як критичної або проривної.
Clinical course and disease outcome in patients with severe COVID-19 receiving remdesivir
Authors: Raeisi Ahmad , Rezaei Zahra , Habibi Zahra , Salimi Maryam , Raeisi Hadi
Published: January 2022

Background and aims: COVID-19 is a pandemic and infectious disease with high morbidity and mortality rates as well as a global spread. This study aimed to investigate the clinical outcomes for patients afflicted with COVID-19 and treated with remdesivir. Methods: In this clinical trial study, patients with severe COVID-19 confirmed by molecular testing and hospitalized at Hajar Hospital of Shahrekord in Iran were divided into standard care group (including 52 patients) and standard + remdesivir group (including 51 patients). The patients were examined for clinical symptoms, laboratory data, as well as mortality and recovery rates during the treatment period. Then the data were analyzed by SPSS version 23 using chi-square, independent t-test and repeated-measures ANOVA. Result: Clinical and laboratory monitoring on days 5, 10, and 14 showed that there was no significant difference between two groups (P>0.05). In addition, there was no significant difference between the two groups in terms of hospitalization duration and ICU rate (58.8% versus 51.9%, P=0.48). The trend of Lymph count and platelet decreased significantly in the standard group (P=0.003, P=0.04, and P=0.03, respectively). Conclusion: Patients with severe COVID-19 were investigated and it was concluded that remdesivir produced no improvement in the remdesivir group compared to the standard group.
The effectiveness of mindfulness-based cognitive therapy and acceptance and commitment therapy on medical science students’ subjective well-being, psychological distress, and emotion regulation
Authors: Shahsavari Googhari Zohreh , Hafezi Fariba , Asgari Parviz , Heidari Alireza
Published: January 2022

Background and aims: Subjective well-being as a major prerequisite of health ensures mental and physical health, a long life, happiness, improved quality of life, and higher socioeconomic indices. The present study aimed to investigate the effectiveness of mindfulness-based cognitive therapy (MBCT) and acceptance and commitment therapy (ACT) on subjective well-being, psychological distress, and emotion regulation in medical science students. Methods: The statistical population of this semi-experimental comprised all female students at Kerman University of Medical Sciences (Iran) in the academic year of 2019-2020. Forty-five students referring to the university counseling center were selected as the sample of the study using convenience sampling and randomly divided into two experimental groups and a control group (n=15 per group). The first and second experimental groups underwent eight 90- and 45-sessions (twice a week) of MBCT and of ACT, respectively. The research instruments included the Subjective Well-being Scale (SWS), the Depression, Anxiety, and Stress Scale, and the Cognitive Emotion Regulation Questionnaire. Results: The results showed that MBCT and ACT were effective in improving the components of subjective well-being and emotion regulation in medical students (P<0.001). Moreover, MBCT and ACT significantly reduced the post-test scores of psychological distress subscales in the experimental group compared to the control group (P<0.001). Finally, no difference was observed between the two therapies in terms of effectiveness. Conclusion: According to the results, MBCT and ACT effectively promoted female students’ subjective well-being and emotion regulation and alleviated their psychological distress.
ĐÁNH GIÁ HIỆN TRẠNG MÔI TRƯỜNG KHU DU LỊCH SINH THÁI PHƯỢNG HOÀNG, HUYỆN VÕ NHAI, TỈNH THÁI NGUYÊN
Authors: Giao Trương Đức
Published: January 2022

Du lịch sinh thái là loại hình du lịch được quan tâm hiện nay, vì tính ưu việt của nó là gắn với thiên nhiên. Tại tỉnh Thái Nguyên, một trong những khu du lịch sinh thái nổi tiếng hiện nay là Khu du lịch sinh thái  Phượng Hoàng, là nơi thu hút lượng khách du lịch ngày càng tăng. Vì vậy cần thiết phải đánh giá hiện trạng môi trường và tiềm năng của khu du lịch sinh thái này, nhất là các giá trị về tài nguyên đất, nước, đa dạng sinh học. Vì vậy, một nghiên cứu đã được thực hiện từ 2019 – 2020 tại Khu du lịch sinh thái Phượng Hoàng bằng việc lấy mẫu đất, nước, không khí của khu hang Phượng Hoàng và phân tích theo các quy chuẩn hiện hành. Kết quả nghiên cứu cho thấy: Môi trường đất và nước suối của Khu du lịch sinh thái Phượng Hoàng không bị ô nhiễm và đều nằm trong tiêu chuẩn cho phép của QCVN 03-MT:2015/BTNMT. Môi trường nước dùng cho mục đích ăn uống của khu du lịch đảm bảo an toàn vệ sinh, các thông số phân tích đều nằm trong tiêu chuẩn quy định theo QCVN 01:2009/BYT. Môi trường không khí trong lành, độ ẩm vừa phải, các chỉ tiêu môi trường đều nhỏ hơn nhiều lần so với giới hạn cho phép của QCVN 05:2013/BTNMT. Như vậy, cho thấy môi trường đất, nước, không khí của Phượng Hoàng đảm bảo yêu cầu cho một khu du lịch sinh thái.
CÁC NHÂN TỐ ẢNH HƯỞNG ĐẾN CHẤT LƯỢNG BÁO CÁO TÀI CHÍNH CỦA CÁC ĐƠN VỊ SỰ NGHIỆP CÔNG TẠI ĐÀ LẠT
Authors: Thảo Lê Vũ Phương
Published: January 2022

Mục đích của bài viết này là xác định các nhân tố ảnh hưởng đến chất lượng báo cáo tài chính của các đơn vị sự nghiệp công lập tại Đà Lạt. Bằng phương pháp nghiên cứu định tính và định lượng, dữ liệu thu thập được trong quá trình nghiên cứu được xử lý bằng phần mềm SPSS. Kết quả nghiên cứu cho thấy có 5 nhân tố ảnh hưởng đến chất lượng báo cáo tài chính của các đơn vị sự nghiệp công trên địa bàn thành phố Đà Lạt, đó là: Các quy định pháp lý về kế toán; Trình độ chuyên môn của người làm công tác kế toán; Cơ sở hạ tầng về kế toán; Sự quan tâm của nhà quản lý; Yêu cầu hội nhập về kế toán khu vực công. Nghiên cứu này sẽ đóng góp vào kho tài liệu nghiên cứu thực nghiệm về lĩnh vực kế toán công nói chung và đơn vị sự nghiệp công tại Đà Lạt nói riêng và hướng đến các biện pháp nhằm nâng cao chất lượng báo cáo tài chính của các đơn vị sự nghiệp công. Kết quả nghiên cứu sẽ giúp cho nhà quản lý nhận diện các nhân tố ảnh hưởng, từ đó có những biện pháp nhằm nâng cao chất lượng báo cáo tài chính, đáp ứng nhu cầu sử dụng khác nhau của các bên có liên quan và nâng cao trách nhiệm giải trình của đơn vị.
DẠY HỌC MÔN TOÁN CAO CẤP THEO HƯỚNG GẮN VỚI THỰC TIỄN NGÀNH NÔNG LÂM NGHIỆP TẠI TRƯỜNG ĐẠI HỌC NÔNG LÂM THÁI NGUYÊN
Authors: Phượng Bùi Linh , Loan Vũ Thị Thu
Published: January 2022

Trong bài báo này, chúng tôi đề cập đến lý thuyết giáo dục toán học gắn với thực tiễn (Realistic Mathematics Education, viết tắt là RME) của Freudenthal – nhà toán học người Hà Lan vào năm 1968. Đầu tiên chúng tôi nghiên cứu cơ sở lý luận và đặc điểm của phương pháp giáo dục gắn với thực tiễn, nghiên cứu các tình huống thực tiễn của lĩnh vực nông, lâm nghiệp liên quan đến học phần Toán cao cấp. Trên cơ sở đó, chúng tôi phân tích và đưa ra ví dụ minh họa về một số cách tiếp cận toán học gắn với thực tiễn nghề nghiệp của sinh viên ngành nông, lâm nghiệp trong dạy học môn Toán cao cấp tại trường Đại học Nông lâm Thái Nguyên. Đánh giá được hiệu quả của phương pháp dạy học gắn với thực tiễn như làm tăng hứng thú học tập, tăng cường năng lực áp dụng toán học vào thực tiễn.
PHÂN VÙNG ĐỊA LÝ TỰ NHIÊN PHỤC VỤ PHÁT TRIỂN DU LỊCH SINH THÁI Ở THÀNH PHỐ ĐÀ NẴNG
Authors: Ngân Phan Kim , Độ Nguyễn Đăng
Published: January 2022

Phân vùng địa lý tự nhiên là cơ sở khoa học và ý nghĩa ứng dụng quan trọng trong việc kiểm kê, tổng hợp và đánh giá tài nguyên thiên nhiên phục vụ mục đích phát triển du lịch nói chung và du lịch sinh thái nói riêng. Vận dụng các nguyên tắc, phương pháp và hệ thống chỉ tiêu phân vùng, với mục đích phát triển du lịch sinh thái, bài báo đã tiến hành phân vùng địa lý tự nhiên thành phố Đà Nẵng, từ đó phân tích đặc điểm phân hóa tự nhiên tại mỗi tiểu vùng. Bản đồ phân vùng địa lý tự nhiên thành phố Đà Nẵng được thành lập ở tỷ lệ 1:100.000, cho thấy thành phố Đà Nẵng có 02 vùng và 04 tiểu vùng: Tiểu vùng đồi núi phía Bắc và Tây Bắc và Tiểu vùng đồi núi phía Tây Nam (thuộc Vùng đồi núi); Tiểu vùng đồng bằng ven biển và Tiểu vùng bán đảo Sơn Trà (thuộc Vùng đồng bằng ven biển và bán đảo). Những đặc trưng cơ bản về điều kiện tự nhiên và tài nguyên thiên nhiên phục vụ du lịch sinh thái tại từng tiểu vùng là cơ sở để đánh giá mức độ thuận lợi và đề xuất các loại hình sinh thái phù hợp ở từng tiểu vùng.
SỰ ẢNH HƯỞNG CỦA CÁC ỨNG DỤNG ĐỔI MỚI SÁNG TẠO ĐẾN LỢI THẾ CẠNH TRANH BỀN VỮNG CỦA CÁC DOANH NGHIỆP TRẺ VIỆT NAM
Authors: Uyên Nguyễn Thị , Mạnh Hoàng Văn , Linh Nguyễn Phương
Published: January 2022

Nghiên cứu được thực hiện nhằm làm rõ cách thức doanh nghiệp trẻ tại các thị trường mới nổi phát triển lợi thế cạnh tranh bền vững thông qua ứng dụng đổi mới sáng tạo. Dựa trên quan điểm lý thuyết nguồn lực, nghiên cứu kiểm định sự ảnh hưởng của đổi mới sáng tạo đến lợi thế cạnh tranh bền vững của doanh nghiệp trẻ ở Việt Nam. Dữ liệu phục vụ cho nghiên cứu được thu thập từ 289 doanh nghiệp trẻ ở Việt Nam. Mô hình cấu trúc tuyến tính bình phương nhỏ nhất từng phần PLS-SEM dựa trên phần mềm Smart-PLS3.0 được sử dụng để phân tích dữ liệu và kiểm định giả thuyết nghiên cứu. Kết quả nghiên cứu cho thấy ba yếu tố của ứng dụng đổi mới sáng tạo gồm đổi mới về chiến lược, về quy trình và hệ thống ảnh hưởng trực tiếp và đáng kể đến lợi thế cạnh tranh bền vững; trong khi sự ảnh hưởng của đổi mới về tổ chức và công nghệ đến lợi thế cạnh tranh chưa được khẳng định trong nghiên cứu này. Phát hiện nghiên cứu không chỉ mang lại bằng chứng thực nghiệm quan trọng đóng góp vào kho tri thức chung mà còn mở ra hướng tiếp cận mới, có ý nghĩa thực tiễn cao cho doanh nghiệp trẻ trong ứng dụng đổi mới sáng tạo và đạt lợi thế cạnh tranh bền vững trong bối cảnh kinh doanh hiện tại.
QUY TRÌNH LẬP NGÂN SÁCH TÁC ĐỘNG ĐẾN HIỆU QUẢ HOẠT ĐỘNG: TRƯỜNG HỢP CỦA CÁC DOANH NGHIỆP SẢN XUẤT TẠI TỈNH LÂM ĐỒNG
Authors: Thảo Nguyên Nguyễn Thị
Published: January 2022

Bài báo nhằm điều tra tác động của quy trình lập ngân sách đối với hiệu quả hoạt động của các doanh nghiệp sản xuất vừa và nhỏ. Ba lĩnh vực chính trong nghiên cứu là lập ngân sách trong các doanh nghiệp vừa và nhỏ, đo lường hiệu quả hoạt động trong các doanh nghiệp vừa và nhỏ và doanh nghiệp vừa và nhỏ. Quy trình lập ngân sách được giải thích và phân tích trên quan điểm lập dự toán ngân sách, kiểm soát ngân sách và sự tham gia vào quá trình lập ngân sách. Dữ liệu nghiên cứu được thu thập từ cuộc khảo sát với 207 nhà quản lý, trưởng phòng, kế toán và nhân viên của 52 doanh nghiệp sản xuất vừa và nhỏ tại tỉnh Lâm Đồng. Nghiên cứu sử dụng phương pháp nghiên cứu định lượng Cronbach’s Alpha, phân tích nhân tố khám phá, phân tích hồi quy đa biến. Kết quả nghiên cứu cho thấy các nhân tố thuộc quy trình lập ngân sách có tác động đến hiệu quả hoạt động của các doanh nghiệp sản xuất vừa và nhỏ, trong đó nhân tố tham gia lập ngân sách có tác động lớn nhất đến hiệu quả hoạt động.
Invertebrados marinos: equinodermos (filo echinodermata)
Authors: Sempere Valverde Juan , Sedano Vera Francisco , Pavón Paneque Altai Carlos , Espinosa Torre Free , Guerra García José Manuel , Abellán Ródenas Pedro , López Martínez María Ángeles , Conradi Barrena Mercedes , Arrébola Burgos José Ramón , López-Fe de la Cuadra Carlos María
Published: January 2022

Este vídeo didáctico sobre taxonomía permite observar los colores y morfología de los equinodermos en su hábitat marino natural. El recurso complementa las prácticas de la asignatura de Zoología e incluye información útil para la identificación de especies representativas de las diferentes Clases del Filo Echinodermata: Asteroidea, Ophiuroidea, Crinoidea, Echinoidea y Holothuroidea.

El recurso es útil para introducir al espectador en la fisiología, taxonomía, biología, ecología y aplicaciones biotecnológicas del Filo Echinodermata. El vídeo supone un complemento perfecto para las prácticas de equinodermos de la asignatura de Zoología I del Grado en Biología, ya que permite visualizar las características morfológicas claves para la identificación de las distintas clases, familias géneros y especies que se trabajan en las prácticas. Además, muestra a este grupo de invertebrados marinos en su medio natural, por lo que se puede observar cómo se desplazan y alimentan. Desde un punto de vista más antropocéntrico, el recurso muestra la importancia de este grupo animal en el desarrollo de aplicaciones biotecnológicas en campos como la industria farmacéutica, óptica y biónica; por lo que resultará de utilidad para la asignatura de Biotecnología Marina del Grado en Bioquímica por la Universidad de Sevilla y la Universidad de Málaga. Finalmente, se señalan cómo la acción humana afecta a las comunidades de equinodermos, tanto en ecosistemas perturbados por la acción humana, donde los erizos pueden proliferar a costa de los bosques de macroalgas, como en el caso de la sobrepesca y el comercio ilegal de holoturias.