bluuebunny/crossref_metadata_2025 huggingface dataset:
Petra/Osiris/Molinspiration and Molecular Docking Analyses of 3-Hydroxy-Indolin-2-one Derivatives as Potential Antiviral Agents
Authors: Hadda Taibi Ben , Rastija Vesna , AlMalki Faisal , Titi Abderrahim , Touzani Rachid , Mabkhot Yahia N. , Khalid Shah , Zarrouk Abdelkader , Siddiqui Bina S.
Published: December 2019

Background:

Studies on the interaction between bioactive molecules and HIV-1 virus
have been the focus of recent research in the scope of medicinal chemistry and pharmacology.

Objective:

Investigating the structural parameters and physico-chemical properties of elucidating
and identifying the antiviral pharmacophore sites.

Methods:

A mixed computational Petra/Osiris/Molinspiration/DFT (POM/DFT) based model has
been developed for the identification of physico-chemical parameters governing the bioactivity of
22 3-hydroxy-indolin-2-one derivatives of diacetyl-L-tartaric acid and aromatic amines containing
combined antiviral/antitumor/antibacterial pharmacophore sites. Molecular docking study was carried
out with HIV-1 integrase (pdb ID: 5KGX) in order to provide information about interactions
in the binding site of the enzyme.

Results:

The POM analyses of physico-chemical properties and geometrical parameters of compounds
3a-5j, show that they are bearing a two combined (O,O)-pockets leading to a special platform
which is able to coordinate two transition metals. The increased activity of series 3a-5j, as
compared to standard drugs, contains (Osp2,O sp3,O sp2)-pharmacophore site. The increase in bioactivity
from 4b (R1, R2 = H, H) to 3d (R1, R2 = 4-Br, 2-OCH3) could be attributed to the existence
of π-charge transfer from para-bromo-phenyl to its amid group (COδ---NHδ+). Similar to the
indole-based reference ligand (pdb: 7SK), compound 3d forms hydrogen bonding interactions between
the residues Glu170, Thr174 and His171 of HIV-1 integrase in the catalytic core domain of
the enzyme.

Conclusion:

Study confirmed the importance of oxygen atoms, especially from the methoxy group
of the phenyl ring, and electrophilic amide nitrogen atom for the formation of interactions.
Clustering of Zika Viruses Originating from Different Geographical Regions using Computational Sequence Descriptors
Authors: Vračko Marjan , Basak Subhash C. , Sen Dwaipayan , Nandy Ashesh
Published: December 2019

Background:

In this report, we consider a data set, which consists of 310 Zika virus
genome sequences taken from different continents, Africa, Asia and South America. The sequences,
which were compiled from GenBank, were derived from the host cells of different mammalian
species (Simiiformes, Aedes opok, Aedes africanus, Aedes luteocephalus, Aedes dalzieli, Aedes
aegypti, and Homo sapiens).

Method:

For chemometrical treatment, the sequences have been represented by sequence descriptors
derived from their graphs or neighborhood matrices. The set was analyzed with three
chemometrical methods: Mahalanobis distances, principal component analysis (PCA) and self organizing
maps (SOM). A good separation of samples with respect to the region of origin was observed
using these three methods.

Results:

Study of 310 Zika virus genome sequences from different continents. To characterize and
compare Zika virus sequences from around the world using alignment-free sequence comparison
and chemometrical methods.

Conclusion:

Mahalanobis distance analysis, self organizing maps, principal components were
used to carry out the chemometrical analyses of the Zika sequence data. Genome sequences are
clustered with respect to the region of origin (continent, country). Africa samples are well separated
from Asian and South American ones.
Use of Synbiotics for Ulcerative Colitis Treatment
Authors: Roselli Marianna , Finamore Alberto
Published: December 2019

Inflammatory bowel diseases, namely Crohn's disease and ulcerative colitis, are currently
considered multifactorial pathologies in which various combined environmental factors act on genetic
background, giving rise to chronic inflammation of the gastrointestinal tract. Ulcerative colitis
is an inflammation of the colon caused by a dysregulated immune response to host intestinal microbiota
in genetically susceptible subjects. Ulcerative colitis has a strong impact on patients' quality of
life, as well as high costs for the health-care system. A great interest on the role of intestinal microbiota
modulation in ulcerative colitis is emerging. Several studies have shown an improvement of
inflammatory markers and symptoms in ulcerative colitis patients through treatments with probiotics
and prebiotics separately. Despite the low number of studies on the treatment of ulcerative colitis
by specific strains of probiotics plus selected prebiotics, i.e. synbiotics, the results are promising,
even if discordant. The mechanism of action in synbiotics supplementation is still unclear and needs
more investigation, although there is a large number of data indicating that the synergism between
probiotics and prebiotics favours the survival and implantation of probiotics into the gastrointestinal
tract with beneficial effects on human health by modulating the inflammatory response and gut
microbiota composition. The aim of this minireview is to describe the main in vitro, animal and
human studies performed up to now, that have used synbiotics to treat ulcerative colitis, and to
highlight limitations and future perspectives.
Hypoglycemic Hemiparesis Masquerading As Ischemic Stroke: When Guideline Fails
Authors: Patel Dhruvkumar M. , Patel Mukundkumar V. , Gurumukhani Jayanti K. , Patel Maitri M. , Mahadevia Himal J. , Gajjar Ritesh A.
Published: December 2019

Background:

Hypoglycemia may rarely present as hemiparesis and sometimes it is difficult to differentiate from ischemic stroke. When random blood sugar (RBS) value is between 50 and 80 mg % in patients presenting with focal neurological deficit, no guideline exists to consider the possibility of hypoglycemia before initiating thrombolytic therapy.

Clinical Case:

A 58-year-old male, who was a known case of diabetes and hypertension, was brought to the emergency room with acute onset of right hemiparesis and dysarthria of 90 minutes duration. His NIHSS Score was 9, blood pressure was 150/90 mm of Hg and RBS was 79 mg% on admission. His CT scan brain was normal and was considered for thrombolysis. Resident doctor not aware of previous sugar repeated RBS before thrombolysis which was surprisingly 60 mg% 60 minutes after the first RBS. Even though he was a candidate for thrombolysis, intravenous 25 % dextrose was administered considering the possibility of hypoglycemia. He made a complete recovery within 20 minutes and thrombolytic therapy was withheld.

In Diabetic patients with focal neurological deficit and RBS less than 80 mg% on admission, RBS should be rechecked and in appropriate cases should be challenged with IV dextrose considering the possibility of hypoglycemia before commencing thrombolytic therapy.
The Role of lncRNAs in Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells
Authors: Wang Jicheng , Liu Shizhang , Shi Jiyuan , Liu Huitong , Li Jingyuan , Zhao Song , Yi Zhi
Published: December 2019

Bone Marrow Mesenchymal Stem Cells (BMSCs) are one of the primary cells found in the
bone marrow, and they can differentiate into osteoblasts, chondrocytes, adipocytes and even myoblasts,
and are, therefore, considered pluripotent cells. Because of their multipotential differentiation, selfrenewal
capability, immunomodulation and other potential activities, BMSCs have become an important
source of seed cells for gene therapy, tissue engineering, cell replacement therapy and regenerative
medicine. Long non-coding RNA (lncRNA) is an RNA molecule greater than 200 nucleotides in length
that is expressed in a variety of species, including animals, plants, yeast, prokaryotes, and viruses, but
lacks an apparent open reading frame, and does not have the function of translation into proteins. Many
studies have shown that lncRNAs play an important role in the osteogenic differentiation of BMSCs.
Here, we describe the role of lncRNAs in the osteogenic differentiation of BMSCs, in order to provide
a new theoretical and experimental basis for bone tissue engineering and clinical treatment.
Research on Psychological Scales Based on the Multitheory Fusion
Authors: Liu Guangdi , Li Yu Chen , Wang Yue , Liu Jing Xiang , Sang Yong Sheng , Zhang Wei , Zhang Le
Published: December 2019

Objective:

This study proposed an innovative approach to simplify the multiple
psychological scales for children and adolescents by integrating statistical methods and item
reflection theory into a structural equation model.

Methods:

First, a psychological scale for adolescents to replace the existing scales optimized for
adults with the Delphi method has been developed. Second, the number of items in the current
group of scales has been reduced.

Result and Conclusion:

A psychological scale for adolescents has been built up that
comprehensively reflects their psychological characteristics in terms of mental state, behavioral
status, emotion & feeling, relationship, and environmental adaptation. This psychological scale has
been simplified and improved its reliability and validity.
DABCO as a Base and an Organocatalyst in Organic Synthesis: A Review
Authors: Jangid Dinesh K.
Published: December 2019

One of the organocatalysts 1,4-diazabicyclo[2.2.2]octane (DABCO) is an excellent solid
catalyst in a number of reactions. It is also a good nucleophile and a base in numerous reactions for the
synthesis of heterocycles. DABCO catalyzes many reactions like cycloaddition reactions, coupling reactions,
Baylis-Hillman reaction, Henry reaction, ring opening reactions, etc. One more advanced feature
of these reactions is that they proceed through environmental friendly pathway. DABCO has
more advantages than other organic catalysts because it is an inexpensive, non.toxic base, an ecofriendly
and a highly reactive catalyst for building of organic frameworks, which produce the desired
products in excellent yields with high selectivity. Many catalytic applications of DABCO have been
reported for the synthesis of an organic framework which has been discussed in this review.
A Fast Encoding Scheme for High Efficiency Video Coding
Authors: Barr Mohammad
Published: December 2019

Background:

High-Efficiency Video Coding (HEVC) is a recent video compression standard. It provides better compression performance compared to its predecessor, H.264/AVC. However, the computational complexity of the HEVC encoder is much higher than that of H.264/AVC encoder. This makes HEVC less attractive to be used in real-time applications and in devices with limited resources (e.g., low memory, low processing power, etc.). The increased computational complexity of HEVC is partly due to its use of a variable size Transform Unit (TU) selection algorithm which successively performs transform operations using transform units of different sizes before selecting the optimal transform unit size. In this paper, a fast transform unit size selection method is proposed to reduce the computational complexity of an HEVC encoder.

Methods:

Bayesian decision theory is used to predict the size of the TU during encoding. This is done by exploiting the TU size decisions at a previous temporal level and by modeling the relationship between the TU size and the Rate-Distortion (RD) cost values.

Results:

Simulation results show that the proposed method achieves a reduction of the encoding time of the latest HEVC encoder by 16.21% on average without incurring any noticeable compromise on its compression efficiency. The algorithm also reduces the number of transform operations by 44.98% on average.

Conclusion:

In this paper, a novel fast TU size selection scheme for HEVC is proposed. The proposed technique outperforms both the latest HEVC reference software, HM 16.0, as well as other state-of-the-art techniques in terms of time-complexity. The compression performance of the proposed technique is comparable to that of HM 16.0.
Synthesis and characterization of metallic sulfide NPs doped graphene oxide for methylene blue adsorption to leuco methylene blue in aqueous mixture
Authors: Dev Sachin , Singh Man
Published: December 2019

Introduction:

The Metal Sulfide Nanoparticles Doped Graphene Oxide Sheets Have Been Studied And Were Used To Adsorb Fluorescent Methylene Blue Dye. Such Mechanism Efficiently Reduces The Dyes And Their Fluorescent Pollutants Through The Positive And Negative Holes. The Metal Sulfide Doped Graphene Oxide Could Be A Most Potential Route To Reduce From Fluorescent To Non-Fluorescent Species To Prevent The Global Warming And Other Pollution Being Caused By Them.

Objectives:

This Study Has Been To Strengthen And Widen The Applications Of Negative And Positive Holes Quick Formation At A Negligible Energy Barrier. Metal Sulfide Nanoparticles Were Doped With Graphene Oxide To Further Strengthen The Semiconducting And To Fastened The Rate Of Adsorption Of Methylene Blue Dye.

Methods:

Graphite Flakes Were Oxidized To Graphite Oxide With High Yield. The Graphite Oxide Was Sonicated In Water To Obtain Graphene Oxide And Doped With Metal Sulfide Nanoparticles In Situ. The Samples Were Characterized With High End Instruments And Used For Adsorption.

Results:

The Metal Sulfide Nanoparticles Were Successfully Doped With Graphene Oxide. The Ftir And Xps Spectra Infer Doping Of Metal Sulfide Nanoparticle In Graphene Oxide. That Enhanced Methylene Blue Adsorption Upto 97%.

Conclusion:

The Common Adsorption Effect Of Methylene Blue With Bare Graphene Oxide And Metal Sulfide Nanoparticles Doped Graphene Oxide Were Studied In This Paper. The Methylene Blue Adsorption Was Maximum (97%) By Cadmium Sulfide Doped Graphene Oxide Compared To Bare Graphene Oxide (87%), Nickel Sulfide Doped Graphene Oxide (79%), And Zinc Sulfide Doped Graphene Oxide (89%). The Metal Sulfide Nanoparticles Have Successfully Enhanced A Semiconductor Mechanism Of Graphene Oxide Especially With 3d And 4d10 Of Cds.
Perceived Treatment Satisfaction and Effectiveness Facilitators Among Patients With Chronic Health Conditions: A Self-Reported Survey
Authors: Volpicelli Leonard Kathryn , Robertson Courtney , Bhowmick Amrita , Herbert Leslie Beth
Published: December 2019

Background

Approximately 50% of patients are nonadherent to prescribed medications. Patient perception regarding medication effectiveness has been linked to improved adherence. However, how patients perceive effectiveness is poorly understood.

Objective

The aim of this study was to elucidate factors associated with perceived treatment satisfaction and effectiveness among patients with chronic health conditions.

Methods

We conducted a descriptive study using a cross-sectional survey design. We administered a Web-based survey to participants with migraine, multiple sclerosis (MS), or rheumatoid arthritis (RA). Patients were recruited from established online communities of Health Union. Descriptive statistics, correlations, and comparison tests were used to examine outcomes.

Results

Data were collected from 1820 patients: 567 with migraine, 717 with MS, and 536 with RA. The majority of participants were female (1644/1820, 90.33%), >40 years old (1462/1820, 80.33%), and diagnosed >5 years ago (1189/1820, 65.33%). Treatment satisfaction and perceived medication effectiveness were highly correlated (r=0.90, P<.01). Overall, three temporal factors were positively correlated with satisfaction or perceived effectiveness: time on current medication (satisfaction rs=0.22, P<.01; effectiveness rs=0.25, P<.01), time since diagnosis (satisfaction rs=0.07, P<.01; effectiveness rs=0.09, P<.01), and time on treatment (effectiveness rs=0.08, P<.01).

Conclusions

Findings validated the strong relationship between treatment satisfaction and perceived effectiveness. Understanding the (1) positive relationship between time and treatment satisfaction and effectiveness and (2) factors associated with determining medication effectiveness can help clinicians better understand the mindset of patients regarding treatment. Clinicians may be better prepared to elicit patient beliefs, which influence medication adherence, for people diagnosed with chronic health conditions.
Co-movimiento entre los índices de confianza del consumidor de México y Estados Unidos 2001-2018
Authors: Díaz Carreño Miguel Ángel , Huerta Quiroz Judith
Published: December 2019

Esta investigación analiza el co-movimiento de los índices de confianza del consumidor de México y Estados Unidos de América durante el periodo 2001- 2018. Dicho co-movimiento fue obtenido mediante el cálculo del coeficiente de correlación de Spearman una vez que las series fueron filtradas a partir de las metodologías de Hodrick-Prescott y Christiano-Fitzgerald. Primero se estimó la correlación entre ambos indicadores de confianza del consumidor. Los hallazgos más relevantes son que la correlación entre ambos índices es elevada en todo el periodo de estudio; sin embargo, durante la recesión de 2001-2003 y, la “Gran Recesión” de 2007-2009, se observó una correlación aún más elevada
Las disparidades entre los sistemas regionales de innovación en Argentina durante el periodo 2003-2013
Authors: Niembro Andrés
Published: December 2019

Las desigualdades regionales y la innovación, como determinante del desarrollo, han sido incluidas en la literatura sobre sistemas regionales de innovación (SRI), pero los aportes empíricos generalmente no han abordado estos fenómenos. El objetivo de este artículo es analizar las desigualdades entre los SRI en Argentina durante el periodo 2003-2013 mediante la elaboración de un índice sintético y diferentes subíndices. Los resultados muestran la persistencia de profundas heterogeneidades entre los SRI, lo que lleva a repensar las políticas públicas en dicho periodo y, a futuro, demandar intervenciones que atiendan las desigualdades territoriales.
Sustentabilidad del desarrollo urbano en la Megalópolis de México: perspectiva desde el análisis espacial
Authors: De Las Heras Gutiérrez Daniel , Adame Martínez Salvador , Cadena Vargas Edel Gilberto , Campos Alanís Juan
Published: December 2019

Este trabajo consiste en un análisis de la sustentabilidad del desarrollo urbano de la Megalópolis del Centro de México, basado en la elaboración de un índice resumen a partir de 17 indicadores con el método de componentes principales, con el que se aplicaron técnicas de análisis espacial (AEDE). Se identificó la presencia de autocorrelación espacial positiva y la existencia de clústeres, indicando una dicotomía entre municipios centrales metropolitanos y periféricos, así como la posición aventajada en niveles de sustentabilidad de la Ciudad de México con respecto a los municipios restantes. Se identificaron los municipios más rezagados  y con necesidad de intervención.
Environment Degradation and Nature’s Reclamation: A Study of Yiro Abari’s in the Absence of Man
Authors: Godwill Yadok Bizuum , Iortyer Manasseh , Gbolagun Vashti Suwa
Published: December 2019

The sermon of eco-activists for long has been about conservation of the flora and fauna, particularly the threatened and endangered species in order to sustain the steady cycle of the ecosystem. However, industrial and economic activities by humans have resulted in the obstruction of the ecosystemic chain. Many Western writers have imposed upon themselves the responsibility of promoting biological and environmental conservation through their art. However, the call for global environmental preservation has been answered weakly by black African writers and critics. This is so because the African writer has been preoccupied with issues of colonialism and corruption. YiroAbari’s In the Absence of Man is set in Jos, the capital of Plateau State of Nigeria. A city that has witnessed massive tin mining activities from the dawn of the 20th century which left vast ponds and infertile lands in the wake of mining. This paper explores the details of the wasted lands due to mining activities. It has become evident in this article that nature has the capacity to re-invent itself through Darwin’s theory of natural selection. The paper therefore posits that nature will always reclaim its lost territories of the earth even after human beings have gone into extinction. It is therefore in man’s interest to protect nature for himself.
Enseñanza de la estructura atómica de la materia en Colombia
Authors: Solbes Matarredona Jordi , Muñoz Burbano Zulman Estela , Ramos Zambrano Germán Enrique
Published: December 2019

Este artículo de investigación presenta los resultados parciales, correspondientes a la primera hipótesis de la investigación doctoral: “Enseñanza de la estructura atómica de la materia en Colombia”. Para ello se presenta un análisis de los Lineamientos Curriculares y los Estándares Básicos de Competencias establecidos por el Ministerio de Educación Nacional y los resultados iniciales del análisis de libros de texto utilizados por docentes colombianos en la enseñanza de esta temática. Se adopta una metodología de análisis documental, que permite concluir que los documentos emitidos por el Ministerio de Educación Nacional no hacen referencia clara y específica a la enseñanza de la Teoría Cuántica y las ciencias modernas y contemporáneas en general, dejando libertad al docente de asumir o no la Teoría y la profundidad con que se haga. Por otra parte, en los libros de texto no se evidencia la Teoría Cuántica como referente teórico necesario en esta unidad didáctica y existen vacíos y errores conceptuales.
Comunidad virtual de práctica para desarrollo de competencias en la construcción de software en equipo
Authors: Martínez Navarro Álvaro Alexander , Jiménez Giraldo Franklin Eduardo , Hernández Pantoja Giovanni Albeiro , Jiménez Toledo Robinson Andrés
Published: December 2019

Este artículo es resultado de la investigación: Incidencia de las Comunidades Virtuales de Práctica en el desarrollo de competencias para la construcción de software en los programas de Ingeniería de Sistemas del Sur-Occidente Colombiano. El objetivo principal de esta investigación fue aportar al desarrollo de competencias para la construcción de software basada en equipo, en los estudiantes de Ingeniería de Sistemas de la Universidad Mariana, mediante el uso de una Comunidad Virtual de Práctica (CVP). Este trabajo, se desarrolló bajo el paradigma cuantitativo, con un enfoque empírico-analítico de tipo descriptivo y propositivo. La población objeto de estudio corresponde a los estudiantes de séptimo y octavo semestre. Como resultado, se identifica el nivel de desempeño de los estudiantes en las dimensiones cognitiva (Saber) y aptitudinal (Saber-hacer) antes de formar parte de la CVP. Se diseña y pone en funcionamiento una CVP, fundamentada en el aprendizaje basado en problemas y estructurada mediante: identidad, práctica y roles que deben cumplir los integrantes; para propiciar en los miembros que la conforman, el desarrollo de competencias para la construcción de software basada en equipo, de manera complementaria al trabajo que se realiza en la Universidad. La investigación permite concluir que la CVP, impacta de manera positiva y hace posible avanzar, a los integrantes que se desempeñaron como miembros activos de la comunidad, en los niveles de logro alcanzados para las dimensiones: cognitiva y aptitudinal; consiguiendo aumentar la posibilidad de vinculación en un mercado laboral para construir software que está en constante crecimiento.
Importância do programa institucional de bolsas de iniciação à docência (PIBID) na formação dos acadêmicos do curso de ciências biológicas
Authors: Silva Junielson Soares da , Fernandes Stephanne Marques Araújo , Soares Romildo Ribeiro
Published: December 2019

A criação de políticas públicas de incentivo à docência, como é o caso do Pibid, tem buscado melhorar a formação inicial de professores e incentivar os licenciandos a seguir a carreira docente. Este trabalho teve como objetivo analisar a importância do Pibid na formação inicial dos licenciandos do curso de Biologia da Universidade Federal do Piauí (UFPI), campus Ministro Petrônio Portela, Teresina. Para isso, foi aplicado um questionário contendo seis perguntas, para 36 bolsistas do Pibid, e a análise dos resultados mostrou que este Programa tem despertado nesses estudantes maior interesse pela docência, além disso, sentem-se mais preparados para atuar no ensino. Conclui-se que o subprojeto Pibid/Biologia da UFPI tem propiciado aos bolsistas, experiências no âmbito da escola de educação básica, despertando nos licenciados, maior interesse pela docência e os tornando mais preparados para as adversidades da profissão.
A formalized evolution of the efficiency of regional higher education systems through the prism of the relationship of inputs and outputs of flow values
Authors: Safiullin M. R. , Abdukaeva A. A. , Yurkov D. V.
Published: December 2019

This study proposes approaches aimed at methodological support for solving the problem of formalized evaluation of the effectiveness of regional higher education systems. The main feature of the work is the use of methods of comparison of «input» and «output» stream values characterizing the parameters of the functioning of the regional higher school. Using the approaches of regulation of the analyzed indicators and the subsequent development on this basis of indices of efficiency, are multi-component calculations that assess the level of generation output 1 unit output parameter, which identifies the financial-economic component of the regional high school. As a result of the implemented assessments, the regions of the Volga Federal district with moderate and strong positions in the sphere of generated effects characterizing their effectiveness in comparison with the invested financial resources are identified.
Book review: “Corporate governance in emerging economies: Theory and practice”
Authors: Cambrea Domenico Rocco
Published: December 2019

This review covers the book titled “Corporate Governance in Emerging Economies: Theory and Practice”, which was edited by Robert W. McGee, Khaled Hussainey, Yaroslav Mozghovyi (Virtus Interpress, 2018; ISBN: 978-617-7309-02-3). The review shortly outlines the structure of the book, pays attention to its strong sides and issues that will be, by the reviewer’s point of view, most interesting for the reader.
Teaching in the Rainforest: Exploring Matses Childrens Affective Engagement and Multisensory Experiences in the Classroom Environment
Authors: Morelli Camilla
Published: December 2019

This paper focuses on Matses children of Peruvian Amazonia and their experiences of formal schooling. Scholars working in Amazonia have emphasised the dysfunctional role of schools in Amerindian societies, suggesting that formal education is predicated upon parameters of learning that often contradict and challenge native understandings. This work, however, largely overlooked children�s lived experience and affective encounters in the classroom, and this is the main focus of this paper. Starting from my own teaching activity in an Amazonian school, I discuss certain problems and failures of schooling with regard to children�s perceptions and lived activities. I suggest that teaching in the field may provide valuable findings on how to enhance the pedagogical possibilities for formal learning and develop creative pedagogical methods. I argue that by recognising learning as a whole bodily and sensorial experience, and acknowledging the emotions of students and teachers, the pedagogical endeavour and results can be creatively enhanced. This does not only apply to schooling indigenous children in the field, but to teaching in general, including the teaching of anthropology in academic environments.
Investigation of accessory elements of representative petrologic radioactivity carriers at Stara Planina, Serbia
Authors: Vakanjac Boris , Jelic Ivana , Rikalovic Milena , Ristic-Vakanjac Vesna , Nikezic Dusan , Naunovic Zorana , Dimovic Slavko
Published: December 2019

The present study deals with the abundance of the most common accessory elements of radioactivity carriers on the Stara Planina mountain at four defined locations. All investigated locations have increased radioactivity, greater than 200 cps, up to 1250 cps. In all examined samples the following elements were detected and their concentrations were determined: Zr, Rb, W, Mo, Sn, Zn, Cu, As, Sb, Ba, Ni, Cr, V, and Ti. The analysis showed that depending on the sample, elevated concentrations of all detected elements except titanium were found. As all localities containing the listed detected elements are located near watercourses, all the present elements, and in particular, those with elevated concentrations can be relatively easily transferred to the environment by water action. Likewise, there is the possibility of eolic erosion from the investigated deposits and tailing dams whereby these chemical elements and/or radionuclides would be distributed to areas away from the primary sources of natural radioactivity. These have a high risk of spreading and therefore have harmful or radioecological effects on the environment. The study indicated a need for adequate monitoring, and risk assessment of the examined locations, which could prevent the distribution of these elements further into the environment. [Projects of the Serbian Ministry of Education, Science and Technological Development, Grant no. III 43009 and Grant no.
Research on water interconnections within the Sar Mountains aquatorium by radioactive hydrogen isotope tritium
Authors: Stanojevic Nenad , Djokic Jelena , Osmokrovic Predrag
Published: December 2019

The waters of two lakes and two streams that dominate in the Sar Mountains aquatorium were analyzed. The tritium profile of soil was also recorded. All samples were taken at approximately the same time, together with samples of precipitation. During the period of taking samples, the ambient temperature conditions were taken into account for ten days around the time of sampling. Monitoring of the seasonal maximum with taking into account the obtained tritium soil profile and the temperature on and around the day of sampling unambiguously showed that all tested water in the Sar Mountains aquatorium is of atmospheric origin and as such unsuitable for any major transformation for commercial purposes.
Soğuk Haddehane Montaj Sürecinin Verimliliğinin Artırılması
Authors: ÇETİN Hatice , ARCAKLIOĞLU Erol , ÇETİN Rukiye
Published: December 2019

1930’lu yıllarda Türkiye’de demir çelik sektörünün
altyapısı atılmış, 1937 yılında Karabük Demir çelik yassı ürün talebini
karşılamak için kurulmuştur. Çelik sektörü özellikle 2001 yılından sonra, hızlı
bir büyüme ivmesi kazanmıştır. Yassı ve yapısal çelik üretim tesislerine artan
yatırımlarla, farklı iş sahaları ortaya çıkmıştır. Bunlardan birisi de soğuk
haddehane kurulum süreçleridir. Soğuk haddehane montajında süreç yönetimi üç
ana bölümde mekanik, borulama ve elektrik olmak üzere çalışılmaktadır. Bu yüzden
birimler arasında iletişimin ve koordinasyonun etkin bir şekilde sağlanması
önemlidir. Bu sürecin doğru planlaması ve sistemlerin organizasyonu etkin bir
şekilde sağlanması proje verimliliğini arttıracaktır. Bu yazıda iki benzer
soğuk haddehane kompleks montajının incelenmesi, proje planlama süreci
üzerinden karşılaştırılmıştır. Öncelikle, bu iki haddehanenin sistemleri
tanımlanmış ve farklılıkları ile benzer yönleri tarif edilmiştir. Proje
detayları karşılaştırılarak, karşılaşılan sorunlar ve bu sorunların muhtemel
sebepleri tanımlanarak, proje yönetim tekniklerinden PERT analizi ile en uygun
toplam montaj süresi belirlenmiştir. Sonrasında üretim hatlarını gerçekleşen
süreler ve çalışan eleman sayıları ile karşılaştırma yapılmıştır.
Digital Branding or Marketing Brand Digitalization
Authors:   Master of Fashion & Luxury Brand Management, Karpykbayeva Anar Bulatovna
Published: December 2019

The problem of brand marketing digitalization emerged as a tool for managing the consistent de-velopment from a simple customer awareness to the formation of his loyalty is revealed in the paper. The loyalty ensures the stability of the company to the actions of competitors aimed at its displacement from the market and luring buyers. The natural pro-cess of the digital environment development and its role in the deployment of the implementation of modern technologies in brand marketing are pre-sented in the study. Modeling was used as the main research method, namely, consideration of the total-ity of facts about the development of the digital environment and the formation of statements re-garding the periodization of the digitalization of brand marketing in the form of a logical model of knowledge representation. It is concluded that as a result of the global evolution of the traditional in-dustry into digitized, the effectiveness of competitor tools increases; there is an increase in the transfer of information to various digital platforms; models of consumer behavior, means of attracting con-sumer attention and protecting the brand are chang-ing. The main result of the study is the formation of a logical scheme of periodization of the digitaliza-tion of brand marketing.
Improvement of Information and Analytical Support of the Criminal Investigation Department of the Ministry of Internal Affairs of Russia
Authors:   Volgograd Academy of the Ministry of Internal Affairs of Russia, Kovalenko Liudmila Yuryevna
Published: December 2019

The paper considers the problem of optimization of some forms of information and analytical support of prevention, solving and investigation of crimes. There are defined advantages and disadvantages of electronic document management system. The tasks to ensure document automation, increase the level of security and information content are out-lined. There was conducted a study on organization of electronic and paper document circulation in the criminal investigation units. The analysis of influ-ence of workload with documents on the efficiency of operational and service activity of law enforce-ment officers, including detectives of criminal inves-tigation department was carried out. Taking into account the specific character of operational and official activities of employees of the Criminal Inves-tigation Department of the Ministry of Internal Af-fairs of Russia there are defined main directions for improvement of forms of law enforcement intelli-gence operations aimed at increasing their effec-tiveness. The study also considers the possibilities of unification and automation of operations with documents and introduction of intelligent software for working with documents generated as part of carrying out law enforcement intelligence opera-tions.
Development of the Human Capital of Youth Within the Framework of the Development Strategy of Municipal Education (Based on the Materials of The Republic of Sakha (Yakutia))
Authors:   North-Eastern Federal University, Okorokova Matrena Pavlovna , Maksimova Tatyana Afanasyevna ,   North-Eastern Federal University
Published: December 2019

The main problems of the development of human capital of youth as one of the the socio-economic development indicators of the region are highlighted in the paper. The demographic, socio-economic and institutional factors of the human capital formation of youth are considered. Documents of strategic importance of municipalities in terms of the suffi-ciency of the system of goals, objectives and activi-ties of the youth policy are analyzed by the authors. In the framework of the study, the Socio-Economic Development Strategies of two municipal entities – “Neryungri Region” and “Aldan Region” of the Re-public of Sakha (Yakutia) are given as an example. It is concluded that in these strategies there are no specific indicators by which to assess the quality of the youth policy implemented, mainly related to the development of general and professional education in the framework of preparing future personnel for industries. An urgent task for local authorities re-mains to ensure the young generation is settled by reducing this group of people migration to other regions of the Russian Federation, creating condi-tions for attracting young people from other regions of Russia, developing business support programs, setting up a youth employment system in accord-ance with its interests, education.
Theoretical Approaches to the Analysis of Decision-Making in Foreign Policy of the Federal Republic of Germany
Authors:   Saint Petersburg Scientific Centre of the Russian Academy of Sciences, Krylova Ekaterina Aleksandrovna
Published: December 2019

The paper discusses theoretical approaches that can be applied in the study of the decision-making in the foreign policy of the Federal Republic of Germany. The analysis of the mechanisms and patterns of the decision-making in the foreign policy in Germany and the EU is already quite popular in the academia abroad, and it is also developing in Russia. A new comprehensive knowledge of the country’s foreign policy process can be obtained through a systemat-ic study of the features of foreign policy decisions in Germany. Some authors investigate general trends in the country’s foreign policy, while others attempt to explain them by opening its “black box”. The built-up bureaucratic model of the system of deci-sion-making in the field of foreign policy in the par-liamentary democracy of the Federal Republic of Germany is called the “Bureaucratic Policy” (“bür-okratische Politik”). The main legitimate actors of such policy are determined by the «Grundgesetz für die Bundesrepublik Deutschland» (The Basic Law for the Federal Republic of Germany). Therefore, the bureaucratic mechanisms of foreign policy, through which initiatives are implemented and decisions are made, need to be carefully studied.
Cooperative Learning: A Systematic Review of the Economy Subject in the Curriculum of Secondary Education
Authors: Morera-fernandez Mercedes , Morera-mesa Aram , L. Morerafumero Armando
Published: December 2019

Cooperative learning (CL) has been applied to different subjects in different educational levels.
Economy as a subject has been introduced recently in the curriculum of secondary schools compared
to other classical subjects such as mathematics or literature. The aim of this research is to
systematically review the application of CL in the teaching of economy in secondary education.
Methods: a search in the Web of Science (WOS), Scopus and EBSCOhost (Academic Search
Complete, Business Source Ultimate, EconLit with full text, ERIC, Library, information science &
technology abstract, PsycArticles, PsycInfo) was carried out from database inception to December
1st, 2019. The query for the search was as follows: “secondary school or secondary education” AND
“cooperative learning or collaborative learning” AND “economy or finances or business”. As
secondary sources of bibliography, we used the reference list from the selected articles. Results: A
total of 428 documents were retrieved from the databases searches. One paper was retrieved from
the secondary sources. EBSCOhost was the database that elicited most documents, 325 against the 29
documents that were retrieved from Scopus and the 74 documents retrieved from WOS. A total of 48
duplicates were elicited from the three databases. After removing the duplicates 380 document were
scrutinized to look for eligibility. No single paper met the criteria except for the paper found through
the secondary sources. Conclusion: Despite of the importance of the subject of economy in the
curriculum of secondary education, only one empirical paper was found in our review. Future
research on this topic should try to fill this gap
Analysis of Students' Science Process Skills on the Concept of Material Classification and its Changes in the Junior High School
Authors: A K Sejatı Feby Unggul , Saputro Sulistyo - , Indrıyantı Nurma Yunita
Published: December 2019

This study aimed to describe the science process skills (SPS) possessed by students, as well as how to
empower them for students. These skills were measured using written assessment instruments. The
research method used in this research was descriptive. Data collection instruments in this study were
multiple-choice test instruments. The research subjects were 38 students of VII class, consisting of 23
females and 15 males in one of the junior high schools in the City of South Tangerang, Banten,
Indonesia. The results showed the reliability of the test questions was 0.76 with a high category; the
level of difficulty, which was in the medium category, was as many as 20 questions, and eight
questions included in the category of easy and difficult. The distinguishing features of the questions
belonged to a quite good category. The SPS owned by students gained an average of 61%, which
means in the good category. The SPS empowerment of students can be done with learning models,
methods, and approaches that support it, such as the Project base learning, Inquiry, and Problem
base Learning experimental methods, and scientific approaches.
Stimuli Responsive Hydrogels: NIPAM/AAm/Carboxylic Acid Polymers
Authors: Işikver Yasemin , Saraydin Dursun
Published: December 2019

Stimuli-responsive hydrogels (SRH) were prepared by using monomers (i.e. N-isopropyl acrylamide; NIPAM and acrylamide; AAm), co-monomers (i.e. methacrylic acid; MPA or mesaconic acid; MFA) and a crosslinker (N, N’-methylene bisacrylamide; N-Bis). SRH have been prepared by thermal free radical polymerization reaction in aqueous solution. Spectroscopic and thermal analyses such as Fourier Transform Infrared Spectroscopy, thermogravimetric analysis and differential scanning calorimetry analysis were performed for SRH characterization. The equilibrium swelling studies by gravimetrically were carried out in different solvents, at the solutions, temperature, pH, and ionic strengths to determine their effect on swelling characteristic of the hydrogels. In addition, cycles equilibrium swelling studies were made with the solutions at different temperatures and at different pH. NIPAM/AAm hydrogel exhibits a lover critical solution temperature (LCST) at 28 oC, whereas NIPAM/AAm-MPA and NIPAM/AAm-MFA hydrogels exhibit a LCST at 31 C and 35 oC, respectively, and the LCST of NIPAM/AAm-MFA hydrogel is close to the body temperature.
Structural and Optoelectronic Properties of Zinc Sulfide Thin Films Synthesized by Co-Precipitation Method
Authors: Choudapur V.H. , Kapatkar S.B. , Raju A.B.
Published: December 2019

Wide bandgap Zinc Sulfide nanocrystals are prepared by a simple co-precipitation method at different precursor concentrations. The influence of sulphur concentration in Zinc sulfide on morphological, optical and electric properties is found to be significant. The Zinc Sulfide nanomaterial was prepared using low-cost starting materials and deionised water as the solvent. As synthesized Zinc Sulfide nanocrystals were analyzed using X-ray diffraction (XRD), Energy Dispersive Spectroscopy (EDS) analysis, UV-Visible Spectrophotometry, Photoluminescence (PL), Scanning electron Microscopy (SEM), Ellipsometry techniques and electric conductivity measurements. XRD patterns revealed that ZnS nanocrystals are polycrystalline, cubic phase with (111) preferred orientation. The obtained crystallites have sizes in the range of 5 to 11 nm. EDS pattern confirms the purity of the films. From optical absorption measurements, it is clear that the direct energy gap decreases from 5.2 to 4.4eV with the increase in sulphur concentration in ZnS and exhibit large quantum confinement effect. Ellipsometry was used to determine the optical constants and film thickness. The films deposited on ITO – coated glass was used to record the IV Characteristics of the films by two probe method. The wide-bandgap, conducting materials have applications in optoelectronic devices such as high-frequency UV detectors and thin-film solar cells.
Treatment of Real Textile Wastewater Using Electron Beam Irradiation
Authors: Duy Nguyen Ngoc , Van Phu Dang , Lan Nguyen Thi Kim , Duoc Nguyen Thanh , Hien Nguyen Quoc , Hiep Bui Nghia , Han Bui Ngoc , Ha Bui Manh
Published: December 2019

Textile wastewater is known to have a large number of hazardous pollutants, intense color and high chemical oxygen demand (COD) concentration. The electron beam method is considered useful in treatment textile wastewater through chemical oxidation process. In this study, three real textile wastewaters (Sample 1: Reactive Black 5, Reactive Red 10, and Reactive Orange 13; Sample 2: Reactive Red 10 and Yellow GR; Sample 3: Reactive Black 5 and Turquoise Blue HF–G) from textile dyeing company in Ho Chi Minh city were treated by electron beam method. The effect of absorbed doses and hydrogen peroxide (H2O2) at different concentrations on the change of pH, removal capacity, COD and five day’s biological oxygen demand (BOD5) were investigated. The results indicated that color, COD, BOD5 and pH decreased with increasing absorbed dose. A sufficient amount of H2O2 in the radiation process could accelerate the color removal process. In the same condition, a color removal efficiency of ~90% was obtained with EB/H2O2, in contrast with color loss by using EB alone (~71%). These results highlighted the potential of EB radiation technology for treatment of textile dyeing wastewater.
Diversity of Diatoms in Phytobenthos Communities of the Shchugor River in the Urals (The Komi Republic, Russia)
Authors: Stenina Angelina , Steryagova Irina
Published: December 2019

The composition of diatom assemblages of epilithon, epiphython and epipelon in the Shchugor River was presented. Biofoulings of rocky substrates, macrophytes, filamentous algae and samples from the surface of bottom sediments were studied. The diatom assemblages had a diverse composition and included 218 species with varieties and forms from 60 genera, 27 families and 12 orders. The order Naviculales (56 taxa) and the family Fragilariaceae (39 taxa) played a major role. The genera Gomphonema (17 taxa), Nitzschia (16), Navicula (14), Eunotia (14) were dominant by the species abundance. The identified diatoms were mostly epiphytes, indifferent to salinity and alkaliphilous species, clean water indicators. The most common community in the river was epilithon, whereas epiphyton distinguished by the most diverse composition. The epipelon was poorly developed, having the lowest number of diatom taxa.

Dominant, subdominant, accompanying species of the diatoms were very similar in different phytobenthos groups, the Sørensen-Czekanowski coefficients varied from 0.70 to 0.81. The dominant species were Achnanthidium minutissimum, Encyonema minutum, Fragilaria gracilis, Gomphonema exilissimum, G. ventricosum, Hannaea arcus, Meridion circulare. The sub-dominant species were Cocconeis placentula, Nitzschia fonticola, Ulnaria ulna and Staurosirella pinnata. Based on the Berger-Parker and Simpson variety indices, the occurrence of taxa in the genera and families in the epiphyton was more uniform. The assessment of benthic diatoms demonstrated that the Shchugor River is a typical mid-mountain river. Diatom communities of epilithon, epiphython and epipelon can be used for the monitoring of ecological status of the river.