bluuebunny/crossref_metadata_2025 huggingface dataset:
Social Support and Optimism as Protective Factors for Mental Health among 7765 Healthcare Workers in Germany during the COVID-19 Pandemic: Results of the VOICE Study
Authors: Schug Caterina , Morawa Eva , Geiser Franziska , Hiebel Nina , Beschoner Petra , Jerg-Bretzke Lucia , Albus Christian , Weidner Kerstin , Steudte-Schmiedgen Susann , Borho Andrea , Lieb Marietta , Erim Yesim
Published: April 2021

Background: The COVID-19 pandemic is impacting mental health worldwide, particularly among healthcare workers (HCWs). Risk and protective factors for depression and generalized anxiety in healthcare workers need to be identified to protect their health and ability to work. Social support and optimism are known protective psychosocial resources, but have not been adequately studied in the context of the COVID-19 pandemic among healthcare workers in Germany. Methods: Within the first wave of the VOICE study (n = 7765), a longitudinal web-based survey study among healthcare workers in Germany, we assessed symptoms of depression (PHQ-2) and generalized anxiety (GAD-2), social support (ENRICHD Social Support Inventory; ESSI), and generalized optimism as well as sociodemographic, occupational, and COVID-19 related variables. Multiple linear regression analyses were conducted to examine associations between the constructs. Results: The analyses revealed that higher levels of social support and optimism were associated with lower levels of depression and generalized anxiety. They showed a higher association with depression and generalized anxiety than demographic or occupational risk factors such as female gender and direct contact with infected individuals. Conclusion: Psychosocial resources such as social support and optimism appear to contribute to successful coping with the COVID-19 pandemic and should be considered in future studies.
Item Reduction, Psychometric and Biometric Properties of the Italian Version of the Body Perception Questionnaire—Short Form (BPQ-SF): The BPQ-22
Authors: Poli Andrea , Maremmani Angelo Giovanni Icro , Chiorri Carlo , Mazzoni Gian-Paolo , Orrù Graziella , Kolacz Jacek , Porges Stephen W. , Conversano Ciro , Gemignani Angelo , Miccoli Mario
Published: April 2021

Body awareness disorders and reactivity are mentioned across a range of clinical problems. Constitutional differences in the control of the bodily state are thought to generate a vulnerability to psychological symptoms. Autonomic nervous system dysfunctions have been associated with anxiety, depression, and post-traumatic stress. Though interoception may be a transdiagnostic mechanism promoting the improvement of clinical symptomatology, few psychometrically sound, symptom-independent, self-report measures, informed by brain–body circuits, are available for research and clinical use. We validated the Italian version of the body perception questionnaire (BPQ)—short form and found that response categories could be collapsed from five to three and that the questionnaire retained a three-factor structure with items reduced from 46 to 22 (BPQ-22). The first factor was loaded by body awareness items; the second factor comprised some items from the body awareness scale and some from the subdiaphragmatic reactivity scale (but all related to bloating and digestive issues), and the third factor by supradiaphragmatic reactivity items. The BPQ-22 had sound psychometric properties, good convergent and discriminant validity and test–retest reliability and could be used in clinical and research settings in which the body perception assessment is of interest. Psychometric findings in light of the polyvagal theory are discussed.
Adjusted Indirect and Mixed Comparisons of Conservative Treatments for Hallux Valgus: A Systematic Review and Network Meta-Analysis
Authors: Ying Jianhua , Xu Yining , István Bíró , Ren Feng
Published: April 2021

Background: Hallux valgus (HV) deformity is a common, potentially debilitating deformity. And evidence with high-quality for the conservative treatments of HV deformity is still required.; AIMS: To compare the effects of different conservative treatments for hallux valgus deformity by using the method of network meta-analysis.; Study Design: A systematic review and network meta-analysis of randomized controlled trials identified by searching PubMed, EMBASE, MEDLINE, OVID, and CINAHL. The included studies should have the characteristics that: (1) participants with hallux valgus deformity of any age (2) conservative treatments (3) Reported the hallux valgus (HVA), the intermetatarsal angle (IMA), the score of the Visual Analog Scale, and the score of Foot Function Index.; Results: 11 studies were included in this review. The agreement between reviewers reached a kappa value of 0.75. The results of the network meta-analysis showed that a combination of exercise and toe separator, night splints, and dry needling are most likely to be the best choice for reducing the hallux valgus angle (HVA) and intermetatarsal angle, and toe separators (with or without exercise), dry needling, and manipulation (with or without ice treatment) have advantages in improving the subjective feeling of patients.; Conclusions: Multi-disciplinary conservative treatments have a great potential for hallux valgus deformity. More research with high-quality is needed to give a comprehensive and reasonable scheme of a holistic and long-term treatment protocol.
The Spectrum of ACS: Towards a More Personalized Approach
Authors: Lüscher Thomas F.
Published: April 2021

On 24 September 1955, Wall Street was in a panic and shares plummeted [...]
Stoichiometry Dependence of Physical and Electrochemical Properties of the SnOx Film Anodes Deposited by Pulse DC Magnetron Sputtering
Authors: Ma Yibo , Zhang Xiaofeng , Liu Weiming , Wei Youxiu , Fu Ziyi , Li Jiuyong , Zhang Xuan , Peng Jingjing , Yan Yue
Published: April 2021

A batch of Sn oxides was fabricated by pulse direct current reactive magnetron sputtering (pDC−RMS) using different Ar/O2 flow ratios at 0.3 Pa; the influence of stoichiometry on the physical and electrochemical properties of the films was evaluated by the characterization of scanning electron microscope (SEM), X-ray diffraction (XRD), X-ray reflection (XRR), X-ray photoelectron spectroscopy (XPS) and more. The results were as follows. First, the film surface transitioned from a particle morphology (roughness of 50.0 nm) to a smooth state (roughness of 3.7 nm) when Ar/O2 flow ratios changed from 30/0 to 23/7; second, all SnOx films were in an amorphous state, some samples deposited with low O2 flow ratios (≤2 sccm) still included metallic Sn grains. Therefore, the stoichiometry of SnOx calculated by XPS spectra increased linearly from SnO0.0.08 to SnO1.71 as the O2 flow ratios increased, and the oxidation degree was further calibrated by the average valence method and SnO2 standard material. Finally, the electrochemical performance was confirmed to be improved with the increase in oxidation degree (x) in SnOx, and the SnO1.71 film deposited with Ar/O2 = 23/7 possessed the best cycle performance, reversible capacity of 396.1 mAh/g and a capacity retention ratio of 75.4% after 50 cycles at a constant current density of 44 μA/cm2.
Evaluation of the Histomorphometric and Micromorphometric Performance of a Serum Albumin-Coated Bone Allograft Combined with A-PRF for Early and Conventional Healing Protocols after Maxillary Sinus Augmentation: A Randomized Clinical Trial
Authors: Trimmel Bálint , Gyulai-Gaál Szabolcs , Kivovics Márton , Jákob Noémi Piroska , Hegedűs Csaba , Szabó Bence Tamás , Dobó-Nagy Csaba , Szabó György
Published: April 2021

The aim of this study was to compare the microarchitecture of augmented bone following maxillary sinus augmentation (MSA) after healing periods of 3 (test) and 6 (control) months using the combination of advanced platelet-rich fibrin (A-PRF) and a serum albumin-coated bone allograft (SACBA). Twenty-six patients with 30 surgical sites who required two-stage MSA were enrolled and grafted with the combination of A-PRF and SACBAs. The surgical sites were randomly allocated to the test or control group. During implant site preparation, 17 bone core biopsy samples were collected from each study group for histological, histomorphometric and micromorphometric analysis. Resonance frequency analysis was performed at the time of implant placement and 6, 8, 10, and 12 weeks postoperatively. The percentage of newly formed bone was 44.89 ± 9.49% in the test group and 39.75 ± 8.15% in the control group (p = 0.100). The results of the µCT analysis showed no significant differences in morphometric parameters between the study groups. The implant stability quotient was not significantly different between the two groups at 10 and 12 weeks postoperatively. Based on these findings, the total treatment time may be reduced by 3 months with the use of A-PRF and SACBAs for two-stage MSA.
Random Forest Approach in Modeling the Flow Stress of 304 Stainless Steel during Deformation at 700 °C–900 °C
Authors: Song Shin-Hyung
Published: April 2021

The alloy 304 stainless steel is used in a wide variety of industrial applications. It is frequently applied in tough environments, such as those involving high temperatures, low temperatures, and corrosive environments. Hence, research on the flow stress behavior of the alloy during deformation under tough environments is critically important to achieving the maximum effectiveness in the application of the alloy. This research presents a study on the flow stress of 304 stainless steel during hot deformation at the temperatures of 700 °C–900 °C under the strain rates ranging from 0.0002/s–0.02/s. For this study, hot tensile experiments are conducted, and the flow stress variations of the alloy are studied with respect to the variations in the strain rate and temperature. Next, the stress behavior was modeled by the traditional Arrhenius-type constitutive equation and random forest algorithm. Then, the flow stresses predicted by different methods were studied by comparing errors. The results showed that the flow stress was modeled more accurately by the random forest algorithm.
Coexistence of Spin Canting and Metamagnetism in a One-Dimensional Mn(II) Compound Bridged by Alternating Double End-to-End and Double End-On Azido Ligands and the Analog Co(II) Compound
Authors: Benamara Nesrine , Setifi Zouaoui , Yang Chen-I , Bernès Sylvain , Geiger David K. , Kürkçüoğlu Güneş Süheyla , Setifi Fatima , Reedijk Jan
Published: April 2021

Two new compounds of general formula [M(N3)2(dmbpy)] in which dmbpy = 5,5′-dimethyl-2,2′-bipyridine, and M = Mn(II) or Co(II), have been solvothermally synthesized and characterized structurally and magnetically. The structures consist of zig-zag polymeric chains with alternating bis-µ(azide-N1)2M and bis-µ(azide-N1,N3)2M units in which the cis-octahedrally based coordination geometry is completed by the N,N’-chelating ligand dmbpy. The molecular structures are basically the same for each metal. The Mn(II) compound has a slightly different packing mode compared to the Co(II) compound, resulting from their different space groups. Interestingly, relatively weak interchain interactions are present in both compounds and this originates from π–π stacking between the dmbpy rings. The magnetic properties of both compounds have been investigated down to 2 K. The measurements indicate that the manganese compound shows spin-canted antiferromagnetic ordering with a Néel temperature of TN = 3.4 K and further, a field-induced magnetic transition of metamagnetism at temperatures below the TN. This finding affords the first example of an 1D Mn(II) compound with alternating double end-on (EO) and double end-to-end (EE) azido-bridged ligands, showing the coexistence of spin canting and metamagnetism. The cobalt compound shows a weak ferromagnetism resulting from a spin-canted antiferromagnetism and long-range magnetic ordering with a critical temperature, TC = 16.2 K.
Artificial Neural Network, Quantile and Semi-Log Regression Modelling of Mass Appraisal in Housing
Authors: Torres-Pruñonosa Jose , García-Estévez Pablo , Prado-Román Camilo
Published: April 2021

We used a large sample of 188,652 properties, which represented 4.88% of the total housing stock in Catalonia from 1994 to 2013, to make a comparison between different real estate valuation methods based on artificial neural networks (ANNs), quantile regressions (QRs) and semi-log regressions (SLRs). A literature gap in regard to the comparison between ANN and QR modelling of hedonic prices in housing was identified, with this article being the first paper to include this comparison. Therefore, this study aimed to answer (1) whether QR valuation modelling of hedonic prices in the housing market is an alternative to ANNs, (2) whether it is confirmed that ANNs produce better results than SLRs when assessing housing in Catalonia, and (3) which of the three mass appraisal models should be used by Spanish banks to assess real estate. The results suggested that the ANNs and SLRs obtained similar and better performances than the QRs and that the SLRs performed better when the datasets were smaller. Therefore, (1) QRs were not found to be an alternative to ANNs, (2) it could not be confirmed whether ANNs performed better than SLRs when assessing properties in Catalonia and (3) whereas small and medium banks should use SLRs, large banks should use either SLRs or ANNs in real estate mass appraisal.
Bivariate Infinite Series Solution of Kepler’s Equations
Authors: Tommasini Daniele
Published: April 2021

A class of bivariate infinite series solutions of the elliptic and hyperbolic Kepler equations is described, adding to the handful of 1-D series that have been found throughout the centuries. This result is based on an iterative procedure for the analytical computation of all the higher-order partial derivatives of the eccentric anomaly with respect to the eccentricity e and mean anomaly M in a given base point (ec,Mc) of the (e,M) plane. Explicit examples of such bivariate infinite series are provided, corresponding to different choices of (ec,Mc), and their convergence is studied numerically. In particular, the polynomials that are obtained by truncating the infinite series up to the fifth degree reach high levels of accuracy in significantly large regions of the parameter space (e,M). Besides their theoretical interest, these series can be used for designing 2-D spline numerical algorithms for efficiently solving Kepler’s equations for all values of the eccentricity and mean anomaly.
Self-Perceived Health, Life Satisfaction and Related Factors among Healthcare Professionals and the General Population: Analysis of an Online Survey, with Propensity Score Adjustment
Authors: Ferri-García Ramón , Rueda María del Mar , Cabrera-León Andrés
Published: April 2021

Healthcare professionals (HCPs) often suffer high levels of depression, stress, anxiety and burnout. Our main study aimswereto estimate the prevalences of poor self-perceived health, life dissatisfaction, chronic disease and unhealthy habits among HCPs and to explore the use of machine learning classification algorithms to remove selection bias. A sample of Spanish HCPs was asked to complete a web survey. Risk factors were identified by multivariate ordinal regression models. To counteract the absence of probabilistic sampling and representation, the sample was weighted by propensity score adjustment algorithms. The logistic regression algorithm was considered the most appropriate for dealing with misestimations. Male HCPs had significantly worse lifestyle habits than their female counterparts, together with a higher prevalence of chronic disease and of health problems. Members of the general population reported significantly poorer health and less satisfaction with life than the HCPs. Among HCPs, the prior existence of health problems was most strongly associated with worsening self-perceived health and decreased life satisfaction, while obesity had an important negative impact on female practitioners’ self-perception of health. Finally, the HCPs who worked as nurses had poorer self-perceptions of health than other HCPs, and the men who worked in primary care had less satisfaction with their lives than those who worked in other levels of healthcare.
Micro: An International Open Access Journal for All of Microscale and Nanoscale Science
Authors: Tamiya Eiichi
Published: April 2021

Since the late 20th century, there has been a special interest in the microscale and nanoscale research investigating and exploiting the physical, chemical, and biological properties of these length-scale systems [...]
Comparative Analysis of the Apple Root Transcriptome as Affected by Rootstock Genotype and Brassicaceae Seed Meal Soil Amendment: Implications for Plant Health
Authors: Wang Likun , Somera Tracey S. , Hargarten Heidi , Honaas Loren , Mazzola Mark
Published: April 2021

Brassicaceae seed meal (SM) soil amendment has been utilized as an effective strategy to control the biological complex of organisms, which includes oomycetes, fungi, and parasitic nematodes, that incites the phenomenon termed apple replant disease. Soil-borne disease control attained in response to Brassicaceae SM amendment is reliant on multiple chemical and biological attributes, including specific SM-generated modifications to the soil/rhizosphere microbiome. In this study, we conducted a comparative analyses of apple root gene expression as influenced by rootstock genotype combined with a seed meal (SM) soil amendment. Apple replant disease (ARD) susceptible (M.26) and tolerant (G.210) rootstocks cultivated in SM-amended soil exhibited differential gene expression relative to corresponding non-treated control (NTC) orchard soil. The temporal dynamics of gene expression indicated that the SM-amended soil system altered the trajectory of the root transcriptome in a genotype-specific manner. In both genotypes, the expression of genes related to plant defense and hormone signaling were altered in SM-amended soil, suggesting SM-responsive phytohormone regulation. Altered gene expression was temporally associated with changes in rhizosphere microbiome density and composition in the SM-treated soil. Gene expression analysis across the two rootstocks cultivated in the pathogen-infested NTC soil showed genotype-specific responses indicative of different defensive strategies. These results are consistent with previously described resistance mechanisms of ARD “tolerant” rootstock cultivars and also add to our understanding of the multiple mechanisms by which SM soil amendment and the resulting rhizosphere microbiome affect apple rootstock physiology. Future studies which assess transcriptomic and metagenomic data in parallel will be important for illuminating important connections between specific rhizosphere microbiota, gene-regulation, and plant health.
Co-Doped NdFeO3 Nanoparticles: Synthesis, Optical, and Magnetic Properties Study
Authors: Nguyen Tien Anh , Pham Thanh Le , Mittova Irina Yakovlevna , Mittova Valentina Olegovna , Nguyen Truc Linh Thi , Nguyen Hung Van , Bui Vuong Xuan
Published: April 2021

In this work, single-phase nanostructured NdFe1−xCoxO3 (x = 0, 0.1, 0.2, and 0.3) perovskite materials were obtained by annealing stoichiochemistry mixtures of their component hydroxides at 750 °C for 60 min. The partial substitution of Fe by Co in the NdFeO3 crystal lattice leads to significant changes in the structural characteristics, and as a consequence, also alters both the magnetic and optical properties of the resulting perovskites. The low optical band gap (Eg = 2.06 ÷ 1.46 eV) and high coercivity (Hc = 136.76 ÷ 416.06 Oe) give Co-doped NdFeO3 nanoparticles a huge advantage for application in both photocatalysis and hard magnetic devices.
Fat and Carbohydrate Interact to Potentiate Food Reward in Healthy Weight but Not in Overweight or Obesity
Authors: Perszyk Emily E. , Hutelin Zach , Trinh Jessica , Kanyamibwa Arsene , Fromm Sophie , Davis Xue S. , Wall Kathryn M. , Flack Kyle D. , DiFeliceantonio Alexandra G. , Small Dana M.
Published: April 2021

Prior work suggests that actual, but not estimated, energy density drives the reinforcing value of food and that energy from fat and carbohydrate can interact to potentiate reward. Here we sought to replicate these findings in an American sample and to determine if the effects are influenced by body mass index (BMI). Thirty participants with healthy weight (HW; BMI 21.92 ± 1.77; M ± SD) and 30 participants with overweight/obesity (OW/OB; BMI 29.42 ± 4.44) rated pictures of common American snacks in 120-kcal portions for liking, familiarity, frequency of consumption, expected satiety, healthiness, energy content, energy density, and price. Participants then completed an auction task where they bid for the opportunity to consume each food. Snacks contained either primarily carbohydrate, primarily fat, or roughly equal portions of fat and carbohydrate (combo). Replicating prior work, we found that participants with HW bid the most for combo foods in linear mixed model analyses. This effect was not observed among individuals with OW/OB. Additionally, in contrast with previous reports, our linear regression analyses revealed a negative relationship between the actual energy density of the snacks and bid amount that was mediated by food price. Our findings support altered macronutrient reinforcement in obesity and highlight potential influences of the food environment on the regulation of food reward.
A Combination of Lactoplantibacillus plantarum Strains CECT7527, CECT7528, and CECT7529 Plus Monacolin K Reduces Blood Cholesterol: Results from a Randomized, Double-Blind, Placebo-Controlled Study
Authors: Guerrero-Bonmatty Rafael , Gil-Fernández Guadalupe , Rodríguez-Velasco Francisco José , Espadaler-Mazo Jordi
Published: April 2021

Background: Dietary supplements have been proposed to help manage blood cholesterol, including red yeast rice (RYR) extracts, plant sterols and stanols, beta-glucans, and some probiotics. This study was conducted to evaluate the efficacy of RYR (containing 10 mg of monacolin K) combined with 109 CFU of three Lactoplantibacillus plantarum strains (CECT7527, CECT7528, and CECT7529). Methods: A 12-week randomized, double-blinded, placebo-controlled clinical trial was conducted. In total, 39 adult patients were enrolled, having total cholesterol (TC) ≥200 mg/dL, and being statin-naïve or having recently stopped statin treatment because of intolerance. Active product or placebo were taken once daily, and subjects were evaluated at baseline, 6, and 12 weeks. Results: Study groups were comparable at baseline, except for history of recent hypercholesterolemia treatment (81% in active vs. 22% in placebo). Changes in LDL cholesterol and TC became significant compared to placebo (mean difference between groups and standard error of the mean = 23.6 ± 1.5 mg/dL, p = 0.023 and 31.4 ± 1.9 mg/dL, p = 0.011, respectively) upon adjusting for the baseline imbalance in hypercholesterolemia treatment. No adverse effects were noted during the study. Conclusion: This combination of 10 mg of monacolin K and L. plantarum strains was well tolerated and achieved a statistically significant greater reduction in LDL-C and TC in the intervention group compared to the placebo, once adjusting for recent history of hypercholesterolemia treatment.
Ultramicronized Palmitoylethanolamide (um-PEA): A New Possible Adjuvant Treatment in COVID-19 patients
Authors: Noce Annalisa , Albanese Maria , Marrone Giulia , Di Lauro Manuela , Pietroboni Zaitseva Anna , Palazzetti Daniela , Guerriero Cristina , Paolino Agostino , Pizzenti Giuseppa , Di Daniele Francesca , Romani Annalisa , D’Agostini Cartesio , Magrini Andrea , Mercuri Nicola Biagio , Di Daniele Nicola
Published: April 2021

The Coronavirus Disease-19 (COVID-19) pandemic has caused more than 100,000,000 cases of coronavirus infection in the world in just a year, of which there were 2 million deaths. Its clinical picture is characterized by pulmonary involvement that culminates, in the most severe cases, in acute respiratory distress syndrome (ARDS). However, COVID-19 affects other organs and systems, including cardiovascular, urinary, gastrointestinal, and nervous systems. Currently, unique-drug therapy is not supported by international guidelines. In this context, it is important to resort to adjuvant therapies in combination with traditional pharmacological treatments. Among natural bioactive compounds, palmitoylethanolamide (PEA) seems to have potentially beneficial effects. In fact, the Food and Drug Administration (FDA) authorized an ongoing clinical trial with ultramicronized (um)-PEA as an add-on therapy in the treatment of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection. In support of this hypothesis, in vitro and in vivo studies have highlighted the immunomodulatory, anti-inflammatory, neuroprotective and pain-relieving effects of PEA, especially in its um form. The purpose of this review is to highlight the potential use of um-PEA as an adjuvant treatment in SARS-CoV-2 infection.
Plant-Derived Nano and Microvesicles for Human Health and Therapeutic Potential in Nanomedicine
Authors: Alfieri Mariaevelina , Leone Antonietta , Ambrosone Alfredo
Published: April 2021

Plants produce different types of nano and micro-sized vesicles. Observed for the first time in the 60s, plant nano and microvesicles (PDVs) and their biological role have been inexplicably under investigated for a long time. Proteomic and metabolomic approaches revealed that PDVs carry numerous proteins with antifungal and antimicrobial activity, as well as bioactive metabolites with high pharmaceutical interest. PDVs have also been shown to be also involved in the intercellular transfer of small non-coding RNAs such as microRNAs, suggesting fascinating mechanisms of long-distance gene regulation and horizontal transfer of regulatory RNAs and inter-kingdom communications. High loading capacity, intrinsic biological activities, biocompatibility, and easy permeabilization in cell compartments make plant-derived vesicles excellent natural or bioengineered nanotools for biomedical applications. Growing evidence indicates that PDVs may exert anti-inflammatory, anti-oxidant, and anticancer activities in different in vitro and in vivo models. In addition, clinical trials are currently in progress to test the effectiveness of plant EVs in reducing insulin resistance and in preventing side effects of chemotherapy treatments. In this review, we concisely introduce PDVs, discuss shortly their most important biological and physiological roles in plants and provide clues on the use and the bioengineering of plant nano and microvesicles to develop innovative therapeutic tools in nanomedicine, able to encompass the current drawbacks in the delivery systems in nutraceutical and pharmaceutical technology. Finally, we predict that the advent of intense research efforts on PDVs may disclose new frontiers in plant biotechnology applied to nanomedicine.
Improving Low-Dispersion Bandwidth of the Silicon Photonic Crystal Waveguides for Ultrafast Integrated Photonics
Authors: Pan Jinghan , Fu Meicheng , Yi Wenjun , Wang Xiaochun , Liu Ju , Zhu Mengjun , Qi Junli , Yin Shaojie , Huang Guocheng , Zhu Shuyue , Chen Xin , Tang Wusheng , Liao Jiali , Yang Heng , Li Xiujian
Published: April 2021

We design a novel slow-light silicon photonic crystal waveguide which can operate over an extremely wide flat band for ultrafast integrated nonlinear photonics. By conveniently adjusting the radii and positions of the second air-holes rows, a flat slow-light low-dispersion band of 50 nm is achieved numerically. Such a slow-light photonic crystal waveguide with large flat low-dispersion wideband will pave the way for governing the femtosecond pulses in integrated nonlinear photonic platforms based on CMOS technology.
Advances on Mode-Coupling Theories, Fabrication Techniques, and Applications of the Helical Long-Period Fiber Gratings: A Review
Authors: Zhao Hua , Li Hongpu
Published: April 2021

In this paper, we have briefly review the developing history and recent advances made with regard to helical long-period fiber gratings (HLPGs) in three aspects, i.e., the mode-coupling theories, the fabrication techniques, and the applications. It is shown that, due to the intrinsic helicity characteristics, which are especially suitable to control the loss, polarization, and orbit-angular-momentum (OAM) states of the light in optical fiber, HLPGs have recently attracted great research interest and have found various applications, such as the mode-converters, the torsion sensors, the band-rejection filters, wave plates, linear- and circular-light polarizers, and OAM mode generators, etc. It is believed that HLPGs and the HLPGs-based devices would find further applications to not only the fields of optical sensors and optical communication, but also other fields such as ultrahigh precision measurement, quantum optics, and biochemistry, etc.
Scheduling and Path-Planning for Operator Oversight of Multiple Robots
Authors: Zanlongo Sebastián A. , Dirksmeier Peter , Long Philip , Padir Taskin , Bobadilla Leonardo
Published: April 2021

There is a need for semi-autonomous systems capable of performing both automated tasks and supervised maneuvers. When dealing with multiple robots or robots with high complexity (such as humanoids), we face the issue of effectively coordinating operators across robots. We build on our previous work to present a methodology for designing trajectories and policies for robots such that a few operators can supervise multiple robots. Specifically, we: (1) Analyze the complexity of the problem, (2) Design a procedure for generating policies allowing operators to oversee many robots, (3) Present a method for designing policies and robot trajectories to allow operators to oversee multiple robots, and (4) Include both simulation and hardware experiments demonstrating our methodologies.
Stinging Nettle (Urtica dioica L.) as an Aqueous Plant-Based Extract Fertilizer in Green Bean (Phaseolus vulgaris L.) Sustainable Agriculture
Authors: Maričić Branka , Radman Sanja , Romić Marija , Perković Josipa , Major Nikola , Urlić Branimir , Palčić Igor , Ban Dean , Zorić Zoran , Ban Smiljana Goreta
Published: April 2021

Plant-based fertilizers, such as liquid plant extracts, contribute to the cultivation of vegetables, particularly in organic production. The objective of this study was to determine if aqueous nettle extract could be successfully used as a fertilizer, applied on the soil and foliarly, in green bean production under field conditions. The hypothesis was that it could successfully replace mineral fertilizers and be integrated into sustainable and organic agriculture. The experiment was conducted at two climatically and pedologically different locations (Zadar and Poreč) throughout two growing seasons (spring and autumn). Two types of aqueous nettle extracts were used: a short-term extract (SE) was prepared by the extraction of wild stinging nettle (183 g 10 L−1 of water) in water for 24 h, while a long-term extract (LE) was prepared at the same ratio with water extraction for 14 days. Both extracts were diluted with water at a ratio of 1:3 (extract:water) before use. The SE was applied foliarly, and LE, by pouring it onto the soil. The abovementioned treatments were compared with mineral fertilization with urea (U) and control (no fertilization (C)). Foliar fertilization with SE proved to be almost as efficient as fertilization with LE, poured onto soil, showing a positive effect on green bean vegetative parameters. Furthermore, aqueous nettle extracts showed a positive effect on the iron accumulation in the leaves.
Understanding Social Impact and Value Creation in Hybrid Organizations: The Case of Italian Civil Service
Authors: Esposito Paolo , Brescia Valerio , Fantauzzi Chiara , Frondizi Rocco
Published: April 2021

The aim of this paper is twofold: first, it aims to analyze what kind of value is generated by hybrid organizations and how; second, it aims to understand the role of social impact assessment (SIA) in the measurement of added value, especially in terms of social and economic change generated by hybrids. Hybrid organizations are a debated topic in literature and have different strengths in responding to needs, mainly in the public interest. Nevertheless, there are not many studies that identify the impact and change generated by these organizations. After highlighting the gap in the literature, the study proposes an innovative approach that combines SIA, interview, interventionist approach and documental analysis. The breakdown of SIA through the five elements of the value chain (inputs, activities, outputs, outcomes, and impact) guarantees a linear definition of the value generated through change with procedural objectivity capable of grasping hybrid organizations’ complexity. The value generated or absorbed is the change generated by the impact measured based on the incidence of public resources allocated. Through the SIA and counterfactual approach, the civil service case study analysis highlights how the value generated by public resources can be measured or more clearly displayed in the measurement process itself.
Agricultural Production in Qatar’s Hot Arid Climate
Authors: Karanisa Theodora , Amato Alexandre , Richer Renee , Abdul Majid Sara , Skelhorn Cynthia , Sayadi Sami
Published: April 2021

Agriculture has played an essential role in the provision of food and has been a major factor in overall economic development for societies around the world for millennia. In the past, agriculture in hot, arid countries like Qatar faced many challenges, the primary one being a dearth of water for irrigation. Historically this severely limited Qatar’s economic development, which was based largely on resource exploitation, pearl fishing, and only more recently, on the exploitation of its oil and gas reserves which subsequently has led to Qatar’s great wealth. This paper gives an overview of the recent evolution of Qatar’s agricultural sector and investigates future trends that tackle the challenges of its hot arid climate and the limited availability of agricultural resources. Specifically, the review analyses Qatar’s potential to develop a national food security strategy based on a significant expansion of food production in the country. We review recent policy actions implemented to address challenges in the food supply chain caused by a 3.5-year blockade imposed by the adjacent Arab Gulf States, discussing the renewed interest in the potential that an enhanced agricultural sector must provide some aspects of food security and the implications for policymakers that would logically ensue.
A Comprehensive Model to Study the Dynamic Accessibility of the Park & Ride System
Authors: Ortega Jairo , Tóth János , Péter Tamás
Published: April 2021

A Park and Ride (P&R) system is an intermodal point where private vehicle users transfer to public transport to make a combined trip. Several researchers have measured the static accessibility of the P&R system. However, studying dynamic accessibility leads to a comprehensive model consisting of a series of elements and steps that allow for travel time analysis in various traffic conditions. Therefore, the purpose of this article is to develop an integrated model that provides a set of procedures which determine the travel origin points of the P&R system, calculate the trips in different traffic conditions (in this article, the results are shown in three scenarios: no traffic (NT), low traffic (LT), and heavy traffic (HT)), and include a hot spot analysis and correlation in order to finally be able to display the dynamic accessibility using geospatial software. The result shows that the accessibility of the P&R system varies depending on the traffic volume and the variation of the accessibility in the different areas that conform to the urban environment. In conclusion, the integrated model helps users decide on the best time to travel to the P&R system, allows transport planners to develop strategies to make the system more functional, and gives an excellent opportunity to develop a travel information system.
Analysis on the Housing Price Relationship Network of Large and Medium-Sized Cities in China Based on Gravity Model
Authors: Wu Guancen , Li Jing , Chong Dan , Niu Xing
Published: April 2021

The relationship among cities is getting closer, so are housing prices. Based on the sale price of stocking houses in thirty-five large and medium-sized cities in China from 2010 to 2021, this study established the modified gravity model and used the method of social network analysis to explore the spatial linkage of urban housing prices. The results show that: (1) from the overall network structure, the integration degree of housing price network in China is still at a low stage, and the influence of housing price is polarized; (2) from the individual network structure, Beijing, Shanghai, Shenzhen, Nanjing, Hangzhou, and Hefei have a higher degree of centrality. Chengdu, Xining, Kunming, Urumqi, and Lanzhou stay in an isolation position every year; (3) from the results of cohesive subgroup analysis, different cities play different roles in the block each year and have different influences on other cities. (4) Emergencies, such as outbreaks of COVID-19, also have an impact on the housing price network. Structural divergence among urban housing prices has become more pronounced, and the diversity of house price network has been somewhat reduced. Based on the above findings, this paper puts forward some recommendations for the healthy development of housing market from the perspective of housing price network.
Feasibility Study of Using X-ray Tube and GMDH for Measuring Volume Fractions of Annular and Stratified Regimes in Three-Phase Flows
Authors: Roshani Gholam Hossein , Muhammad Ali Peshawa Jammal , Mohammed Shivan , Hanus Robert , Abdulkareem Lokman , Alanezi Adnan Alhathal , Nazemi Ehsan , Eftekhari-Zadeh Ehsan , Kalmoun El Mostafa
Published: April 2021

In this paper, the feasibility of using an X-ray tube instead of radioisotope sources for measuring volume fractions of gas, oil, and water in two typical flow regimes of three-phase flows, namely, annular and stratified, is evaluated. This study’s proposed detection system is composed of an X-ray tube, a 1 inch × 1 inch NaI detector, and one Pyrex-glass pipe to model different volume fractions for two flow regimes, annular and stratified. Group method of data handling (GMDH), a powerful regression tool, was also implemented to analyze the obtained data. The obtained results in this work indicate that a simple system based on an X-ray tube and just one NaI detector could be a potential alternative to radioisotope-based systems for separate measurements of gas, oil, and water volume fractions in annular and stratified flow regimes of a three-phase flow.
Uncovering Evidence for Endocrine-Disrupting Chemicals That Elicit Differential Susceptibility through Gene-Environment Interactions
Authors: Wallis Dylan , Truong Lisa , La Du Jane , Tanguay Robyn , Reif David
Published: April 2021

Exposure to endocrine-disrupting chemicals (EDCs) is linked to myriad disorders, characterized by the disruption of the complex endocrine signaling pathways that govern development, physiology, and even behavior across the entire body. The mechanisms of endocrine disruption involve a complex system of pathways that communicate across the body to stimulate specific receptors that bind DNA and regulate the expression of a suite of genes. These mechanisms, including gene regulation, DNA binding, and protein binding, can be tied to differences in individual susceptibility across a genetically diverse population. In this review, we posit that EDCs causing such differential responses may be identified by looking for a signal of population variability after exposure. We begin by summarizing how the biology of EDCs has implications for genetically diverse populations. We then describe how gene-environment interactions (GxE) across the complex pathways of endocrine signaling could lead to differences in susceptibility. We survey examples in the literature of individual susceptibility differences to EDCs, pointing to a need for research in this area, especially regarding the exceedingly complex thyroid pathway. Following a discussion of experimental designs to better identify and study GxE across EDCs, we present a case study of a high-throughput screening signal of putative GxE within known endocrine disruptors. We conclude with a call for further, deeper analysis of the EDCs, particularly the thyroid disruptors, to identify if these chemicals participate in GxE leading to differences in susceptibility.
A Statistical Analysis of Plasma Bubbles Observed by Swarm Constellation during Different Types of Geomagnetic Storms
Authors: Hussien Fayrouz , Ghamry Essam , Fathy Adel
Published: April 2021

Based on the observations of Ionospheric Bubble Index (IBI) data from the Swarm mission, the characteristics of plasma bubbles are investigated during different types of geomagnetic storms recorded from 2014 to 2020. The geometrical constellation of the Swarm mission enabled us to investigate the altitudinal profile of the IBIs during different activity levels in a statistical mean. Results show that the majority of IBIs associated with moderate storms are observed at low altitudes and the probability of observing IBIs at high altitudes (Swarm-B) increases with the increase in storm level. This is confirmed by observing the F2 layer peak height (hmF2) during super storm events at larger altitudes using COSMIC data. The maximum number of IBIs is recorded within the South Atlantic Anomaly (SAA) region with a long duration time and tends to increase only during dusk time. Both the large duration time and number of IBIs over the South Atlantic Anomaly (SAA) suggest that the gradient in the electron density and the depression in the magnetic field are the main factors controlling IBI events. Also, the IBIs at high altitudes are larger at sunset and at low altitudes pre-midnight. In addition, the occurrence of IBIs is always larger in the northern hemisphere than in the southern hemisphere irrespective of the type of storm, as well as during the summer months. Moreover, there is no correlation between the duration time of IBIs and both the altitudinal observation of the IBIs and the storm type. Seasonal occurrence of IBIs is larger during equinoxes and vice versa during solstices irrespective of both the type of storm and the altitude of the satellite. The large number of IBIs during equinoxes agrees with the previous studies, which expect that the large electron density is a developer of steeper ∇n. Large occurrences of super storm IBIs observed within the pre-midnight during summer and at sunset during equinoxes are a novel observation that needs further investigation. Also, the majority of IBIs are observed a few hours after geomagnetic substorms, which reflects the role of the Disturbance Dynamo Electric Field (DDEF) as a main driver of IBIs.
Hearing Loss Caused by HCMV Infection through Regulating the Wnt and Notch Signaling Pathways
Authors: Huang Sheng-Nan , Zhou Yue-Peng , Jiang Xuan , Yang Bo , Cheng Han , Luo Min-Hua
Published: April 2021

Hearing loss is one of the most prevalent sensory disabilities worldwide with huge social and economic burdens. The leading cause of sensorineural hearing loss (SNHL) in children is congenital cytomegalovirus (CMV) infection. Though the implementation of universal screening and early intervention such as antiviral or anti-inflammatory ameliorate the severity of CMV-associated diseases, direct and targeted therapeutics is still seriously lacking. The major hurdle for it is that the mechanism of CMV induced SNHL has not yet been well understood. In this review, we focus on the impact of CMV infection on the key players in inner ear development including the Wnt and Notch signaling pathways. Investigations on these interactions may gain new insights into viral pathogenesis and reveal novel targets for therapy.
Benthic Metabolism in Fluvial Sediments with Larvae of Lampetra sp.
Authors: Nika Nerijus , Zilius Mindaugas , Ruginis Tomas , Giordani Gianmarco , Bagdonas Kasparas , Benelli Sara , Bartoli Marco
Published: April 2021

Lampreys spend their larval stage within fine sand fluvial sediments, where they burrow and act as filter feeders. Lamprey larvae (ammocoetes) can significantly affect benthic-pelagic coupling and nutrient cycling in rivers, due to high densities. However, their bioturbation, feeding and excretion activities are still poorly explored. These aspects were investigated by means of laboratory incubations of intact sediments added with ammocoetes and of animals alone. Oxygen respiration, nutrient fluxes and excretion rates were determined. Individual ammocoete incubations suggested that biomass-specific oxygen consumption and ammonium, reactive phosphorus and silica excretion were size-dependent, and greater in small compared to large individuals. The comparison of ammocoetes metabolic rates with rates measured in intact sediments revealed that ammocoetes activity decreases significantly when they are burrowed in sediments. Furthermore, results suggest that a major fraction of ammonium excreted by ammocoetes was assimilated by benthic microbes or microalgae to overcome in situ N-limitation. Alternatively, part of the excreted ammonium was oxidized and denitrified within sediments, as nitrate uptake rather increased along with ammocoetes density. Ammocoetes excreted reactive phosphorus and silica but such production was not apparent in bioturbated sediments, likely due to microbial or microalgal uptake or to immobilization in sediments.
Introducción
Authors: Cavallero Pablo , Fernández Tomás
Published: April 2021

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Construyendo orden a través de la narración: narrador y narratarios en el Bellum Avaricum de Jorge de Pisidia
Authors: Kröll Nicole
Published: April 2021

El objetivo de este trabajo es analizar las funciones del narrador y de los narratarios en el Bellum Avaricum de Jorge de Pisidia. El artículo postula que a través de la relación jerárquica entre narrador y narratarios, el poeta aspira a reflejar la forma ideal del reinado del emperador Cristiano Heraclio (610-641 d.C.) tanto a nivel secular como espiritual. Por lo tanto, el foco estará puesto en los tres interrogantes que siguen: ¿cómo se representa el narrador?, ¿cómo se dirige a sus narratarios y cómo se comunica con ellos? y ¿cuál es su objetivo ideológico al establecer y estructurar la narración? A partir de estudiar el poema especialmente en lo que respecta a sus técnicas narrativas vinculadas a la retórica y al panegírico, el análisis intenta profundizar en los conceptos sociopolíticos y espirituales de Bizancio al comienzo de siglo séptimo.