bluuebunny/crossref_metadata_2025 huggingface dataset:
INTEGRASI ALIRAN-ALIRAN FILSAFAT PENDIDIKAN DAN WARISAN FILOSOFI KI HAJAR DEWANTARA DALAM KURIKULUM MERDEKA
Authors: Winda Ni Luh Ika Windayani , Suastra I Wayan
Published: August 2024

Artikel ini membahas tentang integrasi aliran-aliran filosofi pendidikan dan warisan filosofi Ki Hajar Dewantara dalam pengembangan Kurikulum Merdeka. Ki Hajar Dewantara, sebagai bapak pendidikan nasional Indonesia, memiliki pandangan filosofis yang kaya, yang mencakup prinsip-prinsip kebebasan, kemandirian, dan keadilan dalam pendidikan. Melalui analisis terhadap aliran-aliran filosofi pendidikan, seperti progresivisme, essentialisme, dan perenialisme, artikel ini menjelaskan bagaimana integrasi tersebut dapat menghasilkan kerangka kurikulum yang holistik dan relevan. Filosofi Ki Hajar Dewantara, yang terutama termanifestasikan dalam konsep "Trikaya Parisudha," diintegrasikan dengan prinsip-prinsip tersebut untuk memperkaya pengalaman belajar siswa dan mengembangkan karakter mereka. Kurikulum Merdeka, sebagai implementasi konkret dari integrasi ini, menekankan pada kebebasan individual, kreativitas, dan penanaman nilai-nilai keindonesiaan. Artikel ini juga menguraikan implementasi praktis dari integrasi ini dalam ranah kurikuler, mulai dari perencanaan pembelajaran hingga penilaian hasil belajar. Hasil penelitian menunjukkan bahwa integrasi aliran-aliran filosofi pendidikan dan warisan filosofi Ki Hajar Dewantara dalam Kurikulum Merdeka memberikan kontribusi positif terhadap pengembangan pendidikan di Indonesia. Dengan memadukan kekayaan warisan filosofis dengan konsep-konsep modern, artikel ini berargumen bahwa Kurikulum Merdeka dapat menjadi landasan yang kuat untuk membentuk generasi yang kreatif, mandiri, dan memiliki identitas nasional yang kuat.
PENGGUNAAN METODE MENTORING COACHING GLICKMAN UNTUK MENINGKATKAN KETERAMPILAN MENGAJAR GURU BAHASA INGGRIS
Authors: Sumali Elly , Haryono Budi , Heryanto Januar , Jap Ellen
Published: August 2024

Penelitian ini mengeksplorasi penggunaan metode mentoring coaching Glickman untuk meningkatkan keterampilan mengajar guru Bahasa Inggris dengan pendekatan kecerdasan majemuk di PG/TK Little Sun School Surabaya.  Peningkatan keterampilan mengajar guru ini penting untuk mendukung agar anak-anak dapat mengembangkan potensi mereka secara optimal. Penelitian ini merupakan Penelitian Tindakan Sekolah (PTS) yang menggunakan metode Kemmis dan McTaggart dalam dua siklus. Subyek penelitian adalah tiga guru Bahasa Inggris dengan obyek penelitian berupa keterampilan mengajar mereka menggunakan pendekatan kecerdasan majemuk. Data dikumpulkan melalui rubrik penilaian, lembar wawancara, dan lembar observasi kelas. Penelitian dimulai dengan diagnosis awal sebelum siklus pertama. Keberhasilan diukur berdasarkan peningkatan nilai keterampilan mengajar, dengan target minimal dua dari tiga guru mencapai level "Cukup". Subyek dibagi berdasarkan tingkatan komitmen dan kemampuan berpikir abstrak dalam Quadran of Development Skill Glickman, untuk memberikan pendekatan mentoring coaching yang sesuai. Pada kondisi awal, dua guru berada pada kriteria "Sangat Kurang" dan satu pada kriteria "Kurang". Setelah dua siklus, keterampilan mengajar mereka meningkat, dengan dua guru mencapai kriteria "Baik" dan satu mencapai kriteria "Cukup". Penelitian ini menyimpulkan bahwa metode mentoring coaching Glickman efektif meningkatkan keterampilan mengajar guru Bahasa Inggris dengan pendekatan kecerdasan majemuk pada anak usia dini.
PENGEMBANGAN E-MODUL INTERAKTIF BERBASIS CANVA PADA MATERI PEMBUATAN DESAIN TEKNIK KOLASE
Authors: Leony Augista Putri , Aini Nurul , Kusumawardani Hapsari , Sintawati Esin
Published: August 2024

Penelitian ini bertujuan untuk mengembangkan media pembelajaran e-modul berbasis canva untuk materi pembuatan desain teknik kolase. Metode penelitian menggunakan model pengembangan ADDIE, yaitu (1) Analaysis, (2) Design, (3) Development, (4) Implementation, dan (5) Evaluation. Produk e-modul yang dihasilkan memuat materi pembuatan desain teknik kolase yang dimulai dengan proses mencari ide, membuat moodboard dan storyboard, dan membuat desain teknik kolase. Hasil pengembangan dinyatakan layak berdasarkan hasil validasi materi dengan persentase skor sebesar 91,6% yang dikategorikan sangat valid. Hasil pengembangan berdasarkan validasi media diperoleh persentase skor sebesar 97,9% yang dikategorikan sangat valid. Hasil implementasi kepada 79 responden mendapatkan persentase 88% pada aspek tampilan media, 88% pada aspek materi, dan 88% pada aspek manfaat. Total persentase berdasarkan hasil implementasi sebesar 88% yang dikategorikan sangat layak sehingga media dapat digunakan untuk pembelajaran guna memudahkan proses pembelajaran di SMK.
PERAN KOMUNITAS GURU DAN REFLEKSI DALAM MENINGKATKAN KETERAMPILAN BERPIKIR KREATIF: STUDI PRAKTIK BAIK GURU
Authors: Upayogi I Nyoman Try , Riandi  , Sumar Hendayana , Ida Kaniawati
Published: August 2024

Penelitian ini mengeksplorasi peran komunitas guru dan refleksi dalam meningkatkan keterampilan berpikir kreatif siswa di tingkat sekolah menengah pertama. Pendekatan yang digunakan adalah studi kasus metode campuran yang menggabungkan data kuantitatif dan kualitatif untuk memberikan pemahaman yang komprehensif mengenai fenomena yang diteliti. Data dikumpulkan melalui tes keterampilan berpikir kreatif, observasi selama pembelajaran, wawancara, dan analisis rekaman video. Hasil penelitian menunjukkan bahwa partisipasi dalam komunitas guru yang reflektif dapat meningkatkan keterampilan berpikir kreatif siswa, terutama dalam aspek fluency dan elaboration. Meskipun peningkatan pada indikator flexibility tidak terlalu signifikan, hasil menunjukkan bahwa lingkungan belajar yang mendukung dan kolaboratif memainkan peran penting dalam merangsang siswa untuk lebih produktif dalam mengemukakan ide-ide mereka. Uji t berpasangan menunjukkan peningkatan yang signifikan antara skor pre-test dan post-test keterampilan berpikir kreatif siswa. Penelitian ini menegaskan pentingnya refleksi dan kolaborasi guru dalam menciptakan pembelajaran yang inovatif dan efektif untuk meningkatkan keterampilan berpikir kreatif siswa.
Exploring The Dynamics of Foreign Employment in Indonesian Local Businesses: Barriers, Experiences, And Opportunities for Cultural Integration
Authors: Hirwa Lionel , Asad Shibli Jamal Shariff
Published: August 2024

This observation delves into the dynamics of foreign employment inside nearby Indonesian agencies, focusing on barriers, stories, and possibilities for cultural integration. Recognizing the significance of know-how in these dynamics, the observer explores the effects along with foreign direct funding (FDI), multinational agencies (MNCs), and nearby research and development (R&D) support. Cultural integration is emphasized, as are the challenging situations that foreign personnel face, such as language barriers, cultural differences, and regulatory hurdles. A qualitative technique is proposed, using purposive sampling and file evaluation to apprehend overseas personnel's experiences. Ethical issues are prioritized. The examination identifies barriers, including criminal and regulatory hurdles, cultural and language challenges, and perceptions toward overseas workers. The stories of foreigners working in Indonesian corporations are examined, specializing in cultural editions, workplace-demanding situations, and aid structures. Recruitment practices, place of work challenges, assistance structures are discussed, along with opportunities for talent switching and knowledge exchange. The look concludes by underscoring the significance of addressing limitations, fostering cultural integration, and maximizing possibilities for the ability to switch and understand alternatives within Indonesian businesses. It gives insights into government guidelines concerning financial development, cultural integration, and collaboration between the authorities and the personal region, imparting suggestions for future research and policy interventions.
GONADOTROPİN+INTRAUTERİN INSEMİNASYON UYGULANAN AÇIKLANAMAYAN İNFERTİLİTE HASTALARINDA GEBELİĞE ETKİ EDEN PREDİKTİF FAKTÖRLER
Authors: Atalay Ayşegül , Yıldırım Gonca , Ateş Aydın Alev
Published: August 2024

Amaç: Kontrollü ovaryen hiperstimulasyon ve intrauterin inseminasyon (KOH+IUI) uygulanan açıklanamayan infertilite hastalarında bazı prediktif faktörlerin gebelik oranlarına etkisini belirleyerek hastalarda tedavi şemasının yeniden düzenlenmesine katkıda bulunmak.
Gereç ve Yöntem: Bu çalışmada, Ocak 2007-Temmuz 2014 tarihleri arasında Kanuni Sultan Süleyman Eğitim ve Araştıma Hastanesi infertilite polikliniğine başvurup açıklanamayan infertilite tanısı alan ve çalışmaya katılma kriterlerini karşılayan toplam 431 hasta ve toplam 874 siklus retrospektif olarak incelendi. Total ileri hareketli sperm sayısı 10 milyon altında olan ve vücut kitle indeksi ≥30kg/m2 olan hastalar çalışma dışı bırakıldı. Tüm hastalara gonadotropinlerle indüksiyon ve HCG ile ovulasyonun tetiklenmesinin ardından 36 saat sonra IUI uygulandı. Primer sonuç ölçütü gebelik oranı olarak kabul edildi. Prediktif faktörler olarak kadının yaşı, erkeğin yaşı, infertilite tipi, infertilite süresi, BMI, adetin 3.günü Folikül stimulan hormon (FSH) ve estradiol(E2) seviyesi ve antral folikül sayısı belirlendi.
Bulgular: 874 siklusta 431 çiftte toplam 88 gebelik elde edilmiştir (%20,4-%10,06/ siklus). Lojistik regresyon analizi yapılan prediktif faktörler içinde kadının yaşı (
Oral Submucous Fibrosis - Case Series
Authors:   Oral Medicine and Radiology, Coorg Institute of Dental Sciences, Virajpet, Coorg, Karnataka, India, Rose Jerry , Kavitha A P , Amirthalingam Karthik
Published: August 2024

Oralsubmucous fibrosis is regarded as a collagen metabolic disorder with an overall increased collagen production and decreased collagen degradation resulting in increased collagen deposition in the oral tissues, and fibrosis due to alkaloid exposure. We report three case reports of oral submucous fibrosis. Clinical findings and histopathologic findings were consistent with the diagnosis of stage 2 oral submucous fibrosis. The patient was educated on the effects of areca nut and chances of malignant transformation. Keywords Malignant Transformation, Oral Submucous Fibrosis, Pathogenesis, Management
Revitalizing Heavily Worn Teeth: A Detailed Case Report of Full Mouth Rehabilitation
Authors:   Prosthodontics and Crown & Bridge, Coorg Institute of Dental Sciences, Virajpet, Karnataka, India, Vishesh N , Salagundi Basavaraj S , Bhavana B L , Pavithra S
Published: August 2024

The management of tooth wear, especially attrition, is becoming a subject of increasing interest in the prosthodontic literature, both from a preventive and a restorative point of view. Dealing with patients who have worn dentition is intricate and challenging. Precise clinical and radiographic assessments, along with a diagnostic wax-up and OVD determination, are pivotal in managing this condition. A crucial element involves establishing the occlusal vertical dimension (OVD) using a systematic method, resulting in a reliable treatment outlook. In this case report attrited teeth were restored with metal-ceramic restorations and a removable partial denture was fabricated for maxillary and mandibular edentulous areas. An occlusal splint was used to protect the restorations. The treatment protocol yielded a pleasing aesthetic and functional outcome. This result can encourage clinicians to seek accurate diagnosis and treatment planning to treat such patients. Keywords Full mouth rehabilitation, Occlusal vertical dimension, Prosthetic dentistry, Prosthodontics, Tooth wear, Worn dentition
Unlocking the Power of Amniotic Membrane in Endodontic Care: A Review Article
Authors:   Department of Conservative Dentistry and Endodontics, Inderprastha Dental College and Hospital, Sahibabad, 201010, Uttar Pradesh, India, Deb Anisha , Kumar Abhinav
Published: August 2024

Amniotic membrane (AM) has garnered significant interest in endodontics for its regenerative properties. This membrane, sourced from the placenta, offers a unique combination of anti-inflammatory, anti-fibrotic, and wound healing properties. In endodontics, AM has shown promise in regenerating damaged periapical tissues, promoting revascularization, and enhancing the success of root canal treatments. It serves as a scaffold for tissue repair and modulates the inflammatory response, aiding in faster healing and reducing post-operative complications. This abstract highlights the potential of AM in revolutionizing endodontic procedures by providing a natural, biocompatible, and effective means for tissue regeneration and repair. Keywords ­ Amniotic membrane, Regenerative Endodontics, Scaffolds, Root End Surgery
Gorlin-Goltz Syndrome with Multiple OKC in a 10-Year-Old Child: A Case Report
Authors:   Vinayaka Mission’s Sankarachariyar Dental College, Vinayaka Mission’s Research Foundation (Deemed to be University), NH 47 Sankari Main Road, Ariyanoor, Salem, 636308, Tamil Nadu, India, Venkatesan Devadhakshayani , Selvarajan Nandhini B , Latkar Yash Suraj , Vinola D
Published: August 2024

Gorlin-Goltz syndrome is rare multi-system disease, which is, characterized by neoplasms and other developmental abnormalities. 1 It is a hereditary condition inherited as an autosomal dominant trait and caused by abnormalities in the PTCH1 (Patched1) gene which is traced to the long arm of chromosome 9q22.3-q31. It is characterized by the triad of multiple baso-cellular epitheliomas, odontogenic keratocysts (OKC) in the jaws and skeletal anomalies. Early diagnosis and treatment are important for long-term prognosis of the syndrome by reducing the severity of cutaneous carcinomas and deformities due to jaw cyst. Current case discusses a 10-year-old child suffering from Gorlin-Goltz syndrome, this case report emphasizes on early diagnosis and prompt treatment of such case. Keywords OKC, Gorlin-Goltz syndrome, Multi nodular radiolucency
Efficiency of Fulvic Acid for Improving Physico-Chemical Properties of Albic Black, Gansu Desert and Shahjiang Black Soils
Authors: Kumar Mahendar , Sootahar Mukesh Kumar , Rajput Ambrin , Memon Muhammad Suleman , Panhwar Muhammad Aslam , Khokhar Khalid Hussain , Suthar Punam , Abbasi Abdul Qudoos , Zeng Xibai , Babar Hafeez
Published: August 2024

Fulvic acids are a crucial component of soil that influence various chemical, biological, and physical aspects of soils as well as increase nutrient availability. We examined that application of plant-derived liquid (PDL) fulvic acid on three low obstacle, typical Chinese soil can improve the soil fertility and enhance the plant growth and nutrients uptake. The pot experiments were carried out on three different Albic (AL), Irrigated Desert (IR) and Shahjiang Black (SH) soils, the Plant-derived Liquid (PDL) fulvic acid (FA) was applied at rates of 0.50% as well as control applied at 0% along with three replications. The results showed that PDL FA significantly increases the SOC content in three soils highest SOC was detected at SH, however the SOC fractions were significantly decreased in AL, SH and no-significant difference was recorded at IR. Similarly, the soil pH was significantly increased in AL and decreased at IR and SH, however, the electrical conductivity of IR decreased and increased in AL and SH comparing with initial soil pH and electrical conductivity. The results also examine that available nitrogen, phosphorus of AL, IR and SH soils were increased, however, available potassium content was decreased in IR and increased at AL and SH comparing with initial values. The highest Ca and Mg content was observed in SH and organic degree compound were found 26.7% AL, 49.2% IR and 18.2%, SH soil, conversely the organic-inorganic composite was observed lower. This study suggests that the PDL FA significantly increases the nutrient content of AL, IR and SH soils comparing with initial soil properties.
Eddington Envelopes: The Fate of Stars on Parabolic Orbits Tidally Disrupted by Supermassive Black Holes
Authors: Price Daniel J. , Liptai David , Mandel Ilya , Shepherd Joanna , Lodato Giuseppe , Levin Yuri
Published: August 2024

Stars falling too close to massive black holes in the centers of galaxies can be torn apart by the strong tidal forces. Simulating the subsequent feeding of the black hole with disrupted material has proved challenging because of the range of timescales involved. Here we report a set of simulations that capture the relativistic disruption of the star, followed by 1 yr of evolution of the returning debris stream. These reveal the formation of an expanding asymmetric bubble of material extending to hundreds of au—an outflowing Eddington envelope with an optically thick inner region. Such outflows have been hypothesized as the reprocessing layer needed to explain optical/UV emission in tidal disruption events but never produced self-consistently in a simulation. Our model broadly matches the observed light curves with low temperatures, faint luminosities, and line widths of 10,000–20,000 km s−1.
A Spectacular Devonian Trilobite Specimen, Dalmanites pratteni, From Illinois Helps Shed Light on How Trilobite Eyes Worked
Authors: Mayer Paul
Published: August 2024

In 1912, the Field Museum purchased Henry Pratten's collection of fossils. One of the specimens was a dalmanitid trilobite with large eyes (Fig. 1) that Pratten collected from the Devil’s Backbone. In 1933, this specimen was described as a new species of trilobite, Dalmanites pratteni (P 16704) (Roy 1933).

Delo (1935) described a new genus of trilobite, Dalmanitoides and assigned it to a new family, Synphorinae. He noted Dalmanites pratteni has similar ornamentation to this genus. Delo (1940) later places D. pratteni in the genus Odontochile.

Other authors refer to it as Dalmanites pratteni (Clarkson and Levi-Setti 1975;Levi-Setti 1975; Frankie et al. 2008). Holloway and De Carvalho (2009) refer to it as ‘Dalmanites’ pratteni and state that this species “probably belongs to the Synphoriinae”.

The stratigraphic position of this specimen was not recorded. Seid et al. (2009) published a detailed geologic map of the Devil’s Backbone. Most of the ridge is Middle Devonian Grand Tower and St. Laurent formations. However, the southern end of the ridge is faulted, and the Lower Devonian Backbone Limestone and Crystal Creek Chert (Emsian) is exposed. Frankie et al. (2008) and Devera et al. (2020) report Dalmanites pratteni occurring from the Crystal Creek Chert, indicating that the original specimen may have been collected here.

One of the most remarkable features of this fossil is the record number of lenses for a Phacopida. Roy (1933) reports 42 rows of eyes, however:

“The exact number of lenses cannot be determined, as not all of them are preserved, nor are the areas which they occupied distinctly outlined. It is, however, certain that there are not less than 770 lenses on each eye.” (Roy 1933).

I used images of the eyes and illustration software to estimate the number of lenses by filling in the geometric pattern they exhibit. I counted 730 lenses on the right eye and 712 lenses on left eye, which is missing a sizable piece (Fig. 2).

The structure of some individual lenses in this specimen can be seen due to differential weathering. Clarkson and Levi-Setti (1975) reported the large round lenses were composed of a doublet structure that followed the principles established by Descartes (1637) and Huygens (1690) to eliminate spherical distortion. This doublet structure allowed the lens to gather more light and focus it on a single point, and strongly indicates that these trilobites had better vision then previously established (Clarkson and Levi-Setti 1975).
Eight years after the Fundão tailings dam collapse: chaos on the muddy banks
Authors: Pereira Cássio Cardoso , Fernandes Stephannie , Fernandes Geraldo Wilson , Goulart Fernando Figueiredo
Published: August 2024

Not applicable
HEALTH EDUCATION: INFORMATION TO PREVENT ACCIDENTS WITH SCORPIONS
Authors: De Matos Ione Maria , Duarte Silva Letícia , Campos Ornelas Rachel , Ferreira Santos Filipe , Silva Vieira Ana Carolina , Silva Maísa
Published: August 2024

We aimed to describe an experience of developing and applying a Didactic Sequence (DS), which included an educational game designed to study scorpion sting prevention. We developed a didactic game titled "Journey against Scorpionism." The DS unfolded in three stages: firstly, we conducted a dialogued expository class to address the topic of scorpionism. In the second stage, we showcased specimens of scorpions to the students. The third stage involved the application of the didactic game. The project was implemented in five public schools in the city of Governador Valadares, Minas Gerais, Brazil, involving both primary and secondary school students. Approximately 150 students took part in the activities, with an average of 30 students per class. We observed a keen interest among the students regarding the topic, with active participation as they shared stories related to scorpion stings or sought clarification on the subject. This engagement fostered a moment of significant interaction. When we presented the scorpions, there was a palpable enthusiasm for learning about the animal's biology. As the students engaged with the didactic game, we noted that it effectively reinforced the knowledge they had acquired. We believe that these educational initiatives have the potential to contribute to the prevention of scorpionism and, consequently, to reduce mortality resulting from such incidents.
PROGRAMAÇÃO METABÓLICA NA LACTAÇÃO ASSOCIADA À RESTRIÇÃO CALÓRICA MODERADA INTERFERE NOS PARÂMETROS SANGUÍNEOS E MORFOMETRIA DO COLO DE RATOS ADULTOS
Authors: Passos Suellen Cristina , Loiola Monica dos Santos Mucio , Branquinho Nayra Thais Delatorre , Natali Maria Raquel Marçal
Published: August 2024

O ambiente nutricional pós-natal pode contribuir significativamente para o excesso de peso, e em roedores a redução do número de filhotes durante a lactação é um modelo clássico de indução precoce de obesidade. O objetivo deste trabalho foi avaliar a programação metabólica e os efeitos da restrição calórica moderada (30%), seguida ou não por alimentação livre, sobre o colo proximal de ratos Wistar machos adultos oriundos de ninhadas reduzidas. Os grupos experimentais (n=05) foram assim distribuídos: controle (G9); controle de ninhada reduzida (G3L); ninhada reduzida e restrição calórica de 30% dos 60 aos 150 dias (G3R) e ninhada reduzida seguida de restrição calórica de 30% dos 60 aos 90 dias com alimentação livre dos 91 aos 150 dias (G3RL). Após 150 dias de idade os animais foram eutanasiados para avaliação do peso corporal, comprimento nasoanal, Índice de Lee, peso dos tecidos adiposos viscerais, parâmetros sanguíneos, tempo de trânsito gastrointestinal, morfometria do colo proximal e quantificação das células caliciformes e serotoninérgicas da mucosa colônica. A redução de ninhada durante a lactação foi efetiva na indução da obesidade em ratos adultos, sendo que a realimentação livre destes animais após período de 30 dias de restrição calórica moderada (30%) mostrou que a programação metabólica na lactação foi mantida nos animais adultos. Entretanto, ratos adultos provenientes de ninhada reduzida quando submetidos à restrição calórica de 30% por período de 90 dias obtiveram melhora nas condições metabólicas, redução da adiposidade visceral e do tempo de trânsito gastrointestinal, com readequação dos parâmetros morfométricos do colo proximal.
Facilitation of constructive intra- and inter-personal relationships: A concept analysis
Authors: Mokoena-De Beer Andile G.
Published: August 2024

Background: The researcher’s previous study indicated that couples in a relationship where one partner is diagnosed with borderline personality disorder (BPD) experience intra- and inter-personal difficulties affecting interaction with self and others. Therefore, constructive intra- and inter-personal relationships are essential to facilitate the mental health of couples in a relationship where one partner is diagnosed with BPD. However, the concept has not been defined and applied in caring for such couples.Aim: The study aims to clarify its meaning by identifying and defining the central concept of ‘facilitation of constructive intra- and inter-personal relationships’.Setting: The researcher used results from a previous study that explored the experiences of couples in a relationship where one partner is diagnosed with a mental illness to identify and define the central concept.Methods: The concept was examined using analysis, synthesis, and inductive reasoning strategies, which were applied in two phases.Results: The central concept of ‘facilitation of constructive intra- and inter-personal relationships’ for couples where one partner is diagnosed with BPD was identified and defined using a dictionary and subject definitions.Conclusion: Identifying and defining the central concept is essential to developing a model to facilitate constructive intra- and inter-personal relationships.Contribution: The concept ‘facilitation of constructive intra- and inter-personal relationships’ is unique in its form and valuable for developing a model that can be used as a guiding tool for psychiatric nurses to facilitate the mental health of such couples. Furthermore, the model could benefit other relationships experiencing intra- and inter-personal challenges.
Continuing professional development barriers and recommendations: Perspectives of audiologists
Authors: Barath Suvishka , Ross Andrew J.
Published: August 2024

Background: Continuing professional development (CPD), a compulsory requirement of the Health Professions Council of South Africa (HPCSA), is undertaken by healthcare professionals (HCPs), including audiologists, to remain up-to-date with the latest developments, technology and best practices within their discipline. However, the low compliance rates of audiologists engaging in CPD need to be investigated to establish the barriers that audiologists encounter as well as possible interventions to improve their participation.Objectives: This study aimed to explore the barriers that audiologists encounter when participating in CPD activities and to highlight their suggestions for improving its uptake.Method: The descriptive qualitative research design entailed the use of semi-structured online interviews with 11 audiologists practising within the private sector in the province of KwaZulu-Natal, South Africa, their responses being thematically analysed.Results: Three barriers were identified, namely: (1) personal, (2) financial and (3) structural barriers, with eight subthemes and nine recommendations provided by participants.Conclusion: It is anticipated that implementing the proposed strategies will address the barriers and allow active engagement of audiologists in their continued education.Contribution: Limited literature has been documented on the barriers that young, private sector audiologists encounter within the South African context while also providing suggestions to address these barriers.
Technologies to improve sperm retrieval in men undergoing micro-TESE for NOA
Authors: Kavoussi Parviz K , Atmoko Widi , Pinggera Germar-Michael
Published: August 2024

Nonobstructive azoospermia (NOA) is considered the most challenging clinical scenario for infertile men and current treatments leave many men unsuccessful at being able to achieve a pregnancy with their partner using their own sperm. Microdissection testicular sperm extraction (micro-TESE) is the choice for men with NOA desiring to father children with their own gametes. Micro-TESE results in the highest numbers of sperm cells retrieved for use with in vitro fertilization/intracytoplasmic sperm injection. With suboptimal micro-TESE success rates of sperm retrieval and then pregnancy and live birth using the retrieved sperm with in vitro fertilization/intracytoplasmic sperm injection, advances to improve outcomes are necessary. This article comprehensively reviews the technologies investigated to date to improve the outcomes for men undergoing micro-TESE.
Role of pericytes in regulating penile angiogenesis and nerve regeneration
Authors: Yin Guo Nan , Ryu Ji-Kan
Published: August 2024

Pericytes are multifunctional mural cells that surround the abluminal wall of endothelial cells and are associated with vascular development, vascular permeability, and angiogenesis. Additionally, pericytes demonstrate stem cell-like properties and contribute to neuroinflammatory processes. Pericytes have been extensively studied in the central nervous system. However, specific mechanisms underlying its involvement in various physiological and pathological conditions, especially in erectile dysfunction (ED), remain poorly understood. Advancements in in vitro and in vitro techniques, such as single-cell RNA sequencing, are expanding our understanding of pericytes. Recent studies have shown that pericyte dysfunction is considered an important factor in the pathogenesis of vascular and neurological ED. Therefore, this study aims to analyze the specific role of pericytes in ED, focusing on diabetic and neurogenic ED. This article provides a comprehensive review of research findings on PubMed from 2000 to 2023, concerning pericyte dysfunction in the process of ED, offering valuable insights, and suggesting directions for further research.
Scoring Criteria for Autoimmune Bullous Diseases: Utility, Merits, and Demerits
Authors: Tseng Henry , Stone Corey , Murrell Dédée F.
Published: August 2024

Background:

Scoring systems play a crucial role in dermatology by providing objective measurements of disease severity, treatment efficacy, and outcome comparisons. In autoimmune blistering diseases (AIBDs), standardized scoring systems are essential for accurate evaluations; however, there is currently a lack of consensus on scoring methods.

Objective:

This literature review explores scoring systems in AIBDs by tracing their development, addressing challenges, and highlighting their role in defining endpoints, regulatory considerations, and clinical trials.

Materials and Methods:

Existing scoring systems for AIBDs, such as the Pemphigus Disease Area Index, Autoimmune Bullous Skin Disorder Intensity Score, Pemphigus Oral Lesions Intensity Score, Oral Disease Severity Score, and Pemphigus Vulgaris Activity Score, are examined for their validity, reliability, and responsiveness. The Bullous Pemphigoid Disease Area Index for bullous pemphigoid is also discussed. The concept of minimal clinically important differences is explored to determine clinically significant improvements in disease severity.

Conclusion:

This review provides a comprehensive understanding of the central role of scoring systems in dermatology and their implications for research and clinical practice in AIBDs.
Pigmentary Changes in Systemic Sclerosis are Associated with More Severe Cutaneous Sclerosis and Severity of Other Systems: A Cross-sectional Study from India
Authors: Mittal Setu , Khaitan Binod K. , Ramam M. , Khanna Neena , Mahajan Rahul , Bhalla Ashu Seith , Singh Manoj K. , Sreenivas V.
Published: August 2024

Background:

Pigmentary changes of the skin in systemic sclerosis in the form of diffuse hyperpigmentation and salt-and-pepper pigmentation are well documented in the literature; however, its association with disease severity and extent of underlying internal organ involvement has not been well studied.

Aims:

To assess the correlation between morphology and extent of pigmentary changes with the degree of cutaneous sclerosis and frequency and degree of major organ involvement.

Methods:

This was a cross-sectional descriptive study conducted in a tertiary care teaching hospital from December 2014 to November 2016. Consecutive patients of systemic sclerosis attending the outpatient department were screened, and patients satisfying the diagnosis as per the American Rheumatism Association criteria were recruited. Skin sclerosis was quantified using modified Rodnan skin score (MRSS), whereas pigmentary changes were calculated in terms of percentage of body surface area involved by rule-of-nine method. Investigations were carried out depending on organ involvement and as per respective specialty consultations with focus on pulmonary, cardiac, and gastrointestinal systems.

Results:

Of the 50 patients recruited, all had cutaneous involvement in the form of binding down of skin, followed by pigmentary changes. MRSS was significantly higher in patients with any pigmentary alteration (P = 0.03) compared to those without any pigmentary changes. There was a rising trend in between the MRSS severity and the proportion of patients with hyperpigmentation, and it was statistically significant (P = 0.04). Among systemic involvement, lung was involved in the form of interstitial lung disease in 94% patients (n = 47). However, skin pigmentation of any type was associated with lower high-resolution computed tomography scores (P = 0.02).

Conclusion:

This study shows that in systemic sclerosis patients presenting with pigmentary skin manifestations, cutaneous sclerosis is significantly higher.
Sarcoidosis and Polymethyl Methacrylate (PMMA) Granulomas following COVID-19 Vaccination (ChAdOx1): Successful Treatment with Tofacitinib
Authors: Ianhez Mayra , Miot Hélio A , Caetano Lívia VN , Paula Henrique Moura de , Freire Giselle GS , Torres Pedro PTS
Published: August 2024

Sarcoidosis and complications related to fillers have been reported following the COVID-19 vaccination. Additionally, cutaneous sarcoidosis has been observed around polymethyl methacrylate (PMMA) injection sites. Foreign-body reactions to PMMA can occur simultaneously with systemic sarcoidosis, suggesting a shared pathogenic mechanism between both conditions. To report a case of sarcoidosis and PMMA granulomas following COVID-19 vaccination (ChAdOx11), successfully treated with tofacitinib. We present a 59-year-old woman who developed systemic sarcoidosis and a granulomatous reaction to PMMA filler following the COVID-19 vaccination (ChAdOx11). Notably, both PMMA and the vaccine were potential triggers for sarcoidosis. Treatment with tofacitinib produced marked improvement in both the cutaneous and pulmonary involvement of sarcoidosis and the granulomatous reaction to PMMA. This successful outcome suggests tofacitinib, a pan-JAK inhibitor, an alternative treatment for cutaneous and systemic sarcoidosis, as well as a potential therapy for granulomatous complications of dermal fillers, such as PMMA.
100 Most-Cited Articles in Vitiligo: A Bibliometric Analysis
Authors: Attal Zoé Gabrielle , Gabay Sapir Itzhaki , Peles Galia , Horev Amir
Published: August 2024

Introduction:

Vitiligo is a skin disease affecting melanocytes, characterised by the development of depigmented skin lesions.

Methods:

We used bibliometric analysis (BA) to identify high-quality research articles on vitiligo using criteria such as total citations, annual citations (AC) and journal impact factors. We extracted the 100 most-cited articles on vitiligo using the Web of Science database and analysed the results using Microsoft Excel 2019. Our search was limited to manuscript titles or abstracts containing the keyword ‘vitiligo’. The data extracted information such as title, author, year of publication, journal of publication, total citations and research area. We also calculated the AC rate to account for bias.

Results:

A total of 6,189 studies were retrieved. The 100 most-cited articles were published between 1976 and 2017. Of those, 75 were original articles, with the research foci being mainly pathogenesis (29%) and treatment (26%). The US was the most prolific publisher overall. We separately retrieved the highest cited data from 2018 to 2022 and tabled the top 10. Of those, 50% were original articles.

Discussion:

Our BA shows that developed countries published most of the vitiligo literature. Additionally, recent research has focused on targeted treatment approaches. We also highlight the increasing paediatric vitiligo research, specifically regarding therapies.
50 Years of Existence of X-rays in Orthopedic Operation Theater: A Review
Authors: Khan Abdul Qayyum , Abbas Mohd Baqar , Anwer Adnan , Khan Gular Navi , Akhtar Mohd Naseem , Chowdhry Madhav
Published: August 2024

The radiation hazards evaluation is very important for justifying and ensuring satisfactory protection. The surgeon may receive exposure to the hands from the primary beam and to the rest of the body from the scattered beam. In academic institutions, one should always keep in mind that surgeons-in-training and technicians may be exposed to excessive radiation. One has to be also very careful with pediatric and pregnant patients. The radiosensitivity of pediatric patients is 10 times more compared with adults. Issues concerning X-ray exposure should be understood in the correct perspective and it should not create undue apprehension in the minds of surgeons, which will forbid the optimum use of this invaluable modality. It is very important that practitioners should be aware of the effective dose and should ensure that they use it wisely and effectively. The International Commission on Radiological Protection recommendation identified two types of effects against which protection is required. “Stochastic” effects are those for which the probability of an effect occurring, rather than its severity, is regarded as a function of dose without threshold, whereas “non-stochastic” (deterministic) effects are those for which the severity varies with the dose and for which a threshold may occur. Most importantly a piece of practical advice to orthopedic surgeons and operation theater personnel for optimum radiation protection should be given as reported by various authors. Recommended limits of exposure to ionizing radiation as advised by the National Council on Radiation Protection are updated from time to time as new information becomes available. Radiation protection infrastructure in India is constantly being strengthened based on experience and continued research and development activities at Bhabha Atomic Research Centre (BARC), Mumbai, and is keeping pace with the increasing use of radiation in radiotherapy, diagnosis, nuclear medicine, and industrial radiography. BARC has developed in-house thermoluminescent dosimeters (TLDs) and an automatic reader system for occupational radiation monitoring. Personnel monitoring of over 70,000 occupational workers is carried out using TLD.
A Case Report on a Patient with a Primary Giant Cell Tumor of the Great Toe
Authors: Tomar Vishvendra , Adnan Mohd , Khan Azad
Published: August 2024

Despite their benign nature, giant cell tumors (GCT) are locally aggressive bone tumors with a high recurrence rate. The most afflicted bones are the distal radius, distal femur, proximal tibia, and humerus and the commonly affected age group is 20–40 years. A bone GCT in the distal aspect of the proximal phalanx of the great toe, and fifth decade is exceedingly rare. In such circumstances, the standard therapy for GCT in such instances is extended curettage.
Intra-neural Ewing Sarcoma of the Radial Nerve Presenting as Wrist
Authors: Kala Prakash Chandra , Dave Aniket , Katrolia Deepti , Saxena Suvinay , Poonia Dharma Ram
Published: August 2024

Intra-neural Ewing sarcoma is an extremely rare tumour and only a few isolated case reports exist in the literature. A 32-year-old South Asian male presented with wrist and finger drops of 3 months duration. Further evaluation with ultrasonography and magnetic resonance imaging revealed a tumour of the radial nerve in the arm. A wide excision of the tumour was performed, and the radial nerve was reconstructed with cabled nerve grafts. A diagnosis of extra-osseous Ewing sarcoma (EES) was made after histopathological evaluation using immunohistochemistry techniques. The patient subsequently received chemotherapy and after 5 months, he is disease-free and pain-free. However, there has been no motor recovery yet. Clinical findings and imaging can help and characterise the tumour, but histopathology and analysis for EWSR1 gene rearrangement are essential to confirm the diagnosis. Wide surgical excision and chemotherapy are the mainstay of managing neural EES.
Atypical Variants of Spinal Dysraphism: A Case Series
Authors: Badejo Oluwakemi Aderonke , Shokunbi Matthew Temitayo , Adeolu Augustine Abiodun , Oderinde Idris Olanrewaju , Akinmoladun Janet Adetinuke , Ogbole Godwin Inalegwu
Published: August 2024

The aim of this study is to present and discuss atypical instances of spina bifida (SB) within a Nigerian paediatric cohort, highlighting their distinctive clinicoradiological features. Additionally, a brief literature review is provided to contextualise these congenital anomalies. This series comprises eight rare cases of SB managed in a Nigerian neurosurgical facility. Additionally, a brief literature review is provided to contextualise these congenital anomalies. This case series comprises eight rare cases of SB managed in a Nigerian neurosurgical facility. Amongst these, four cases exhibited segmental spinal dysgenesis (SSD; one thoracolumbar, one lumbar, and two sacral). Each of these cases demonstrated diverse associated musculoskeletal, cutaneous, and perineal anomalies, accompanied by varying degrees of neurological dysfunction. Other cases included lipomyelomeningocele (LMMC), human tail (HT), membranous meningocele, and myeloschisis (MSS). Autonomic dysfunction was a common feature in all of the cases, whilst two of the patients presented with congenital kyphotic spinal deformity. Lower limb anomalies varied, including congenital talipes equinovarus deformity, pes planus, congenital calcaneovagus deformity, rocker bottom feet, clinodactyly, and tetrapolydactyly. Remarkably, none of the patients exhibited clinical features indicative of hydrocephalus. SSD, LMMC, HT, membranous meningocele, and MSS represent atypical forms of SB in the Nigerian paediatric population. Early neuroimaging of patients with suspected spinal dysraphism is crucial, as it may reveal a spectrum of diverse vertebral anomalies associated with this neurological condition within the African population.
Thyroid dysfunction in Egyptian patients with liver cirrhosis: a cross-sectional study
Authors: Basiony Walaa T. , Elwan Nadia M. , Watany Mona M. , Elkadeem Mahmoud Z. , Hawash Nehad I.
Published: August 2024

Background

Owing to the liver’s important role in thyroid hormone metabolism. Concerns were raised about the effect of the degree of liver cirrhosis on thyroid functions. This study aimed to assess the effect of liver cirrhosis on thyroid functions and the relation between thyroid dysfunctions and both the severity of liver disease and associated clinical presentations.

Aim

To assess the effect of liver cirrhosis on thyroid function and its relation to the severity of liver disease.

Patients and methods

This was a cross-sectional study conducted on 70 patients with liver cirrhosis (35 cirrhotic compensated patients and 35 decompensated patients) in addition to 20 healthy control subjects. Serum free triiodothyronine (FT3), free thyroxine, and thyroid stimulating hormone (TSH) levels were measured. The severity of liver cirrhosis was assessed by Child-Turcotte-Pugh (CTP) and Model for End-Stage Liver Disease (MELD) scores. Statistical analysis was done to compare groups and evaluate the association of thyroid function tests with CTP and MELD scores.

Results

FT3 and free thyroxine levels showed significant differences among studied groups (P=0.013 and <0.001, respectively) as both were decreased in decompensated patients compared with control group, while only FT3 was significantly decreased in compensated patients than the control group. While TSH levels showed no significant difference (P=0.062). FT3 and TSH levels showed a significant negative correlation to CTP and MELD scores.

Conclusion

Liver cirrhosis was associated with abnormalities in thyroid function tests that may be an additive cause to complaints in those patients. Being inversely related to the severity of the liver condition both TSH and FT3 needed to be followed-up as the liver condition deteriorated.
Diagnostic value of multimodal ultrasonographic techniques in evaluation of lymphadenopathy in the neck
Authors: Nooman Alaa A. , Elshafie Khalid I. , Reda Alaa M. , Dawoud Rasha M.
Published: August 2024

Background

Recent ultrasound (US) imaging techniques, including high-resolution gray-scale, color, power, pulsed Doppler, and strain sono-elastography, are recent modes for US evaluation.

Aim

This prospective study aimed to review the value of the recent US modes in differentiating causes of lymph node enlargement in benign and malignant conditions.

Patients and methods

The study included 30 patients with enlarged cervical lymph nodes throughout the period from August 2022 to September 2023. Multimodal US techniques were used for all cases.

Results

In benign lesions, the lymph node size was taken. The shape index range was 0.31–0.66 with a mean=0.48 ± 0.9. Using Doppler US, they showed elevated hilar flow without peripheral vascularity. Using elastography, these nodes gave soft strain values range=0.60–1.00 with a mean=0.80 ± 0.2. In malignant lesions, the lymph node shape index range=0.55–0.81 with a mean=0.68 ± 0.4. Using Doppler, the nodes showed increased vascularity in most patients and avascular nodes in others. Using elastography, these nodes gave hard strain values with a range=1.70–11.75 and a mean=4.70 ± 5.0.

Conclusion

The use of multimodal US imaging (gray scale, color Doppler, pulsed Doppler, power Doppler, and elastography), in addition to the clinical history of the disease, differentiates benign from malignant causes of lymph nodes enlargement and are useful in selecting the lymph node for fine-needle aspiration cytology or biopsy.
The gestational outcome in a low-implanted gestational sac in the first trimester in primigravidae
Authors: Srour Kholoud A.M. , Hagras Ahmed M. , Eldorf Ayman A. , Elhawary Tarek M.E.
Published: August 2024

Background

The pregnancy stage is known as implantation, when the attachment occurs between the embryo and the uterine wall.

Aim

This study aimed to evaluate the incidence of abortion and the gestational outcome in a low-implanted gestational sac in the first trimester in primigravidae till 28 weeks.

Patients and methods

The observational cohort prospective study was conducted on 100 primigravidae pregnant women with low-lying-implantation pregnancies in the first trimester. When we used the research, we omitted the patient’s name. It was only for scientific purposes that the data from this research was analyzed; it was not utilized for any other purpose.

Results

First-trimester bleeding, it occurred more in cases that had a gestational sac localized 0–0.5 cm from the internal ostium (OS) in 10 cases followed by cases who had a gestational sac localized more than 0.5–1 cm from the internal OS in 12 cases. Twelve cases had an abortion in the first trimester and eight cases had an abortion in the second trimester. Gestational outcome at the 28th week, 74 cases continued to the 28th week of gestation, 20 cases were aborted before the 28th week, and six cases were missed. Mode of delivery: 49 cases had cesarean section and 25 cases had normal delivery.

Conclusions

In primigravidas situations, the low-implanted gestational sac may increase the risk of bleeding depending on the distance from the internal OS, affecting the future position and development of the placenta with no additional risk to maternal and fetal survival.