bluuebunny/crossref_metadata_2025 huggingface dataset:
Campur Kode Pada Gelar Wicara Mata Najwa Episode “Belajar dari Buya Hamka” dan Implikasinya Terdahap Pembelajaran Bahasa
Authors: Azizah Niken Putri , Abasa Rafik M , Madi Nasrullah La , Kasim Suhardi
Published: July 2024

The formulation of the problems in this study are (1) How is the form of inward code mix and outward code mix in Gelar Wicara Mata Najwa Episode "Belajar dari Buya Hamka" (2) How is the implication of code mix in language learning. The research objectives to be achieved are to know the form of inward code mix and the form of outward code mix in Gelar Wicara Mata Najwa Episode "Belajar dari Buya Hamka" and to know the implications of code mix on language learning. The method used in this research is descriptive qualitative method. The data in this research is the dialog of moderators and speakers. The data source used in this research is Mata Najwa Talk Show Episode "Learning from Buya Hamka". Based on data analysis and conclusions, it is known that (1) The form of inward code mix in Gelar Wicara Mata Najwa Episode "Belajar dari Buya Hamka" is the use of two languages in one dialog, namely Indonesian and local languages. (2) The form of outward code mix in Gelar Wicara Mata Najwa Episode "Belajar dari Buya Hamka" is the use of two languages in one dialog, namely Indonesian and foreign languages. (3) Code mixing is implied in Indonesian language learning in the form of learning media produced, namely posters and slogans related to the results of code mixing in Gelar Wicara Mata Najwa Episode "Belajar dari Buya Hamka".
Implementasi Model Pembelajaran Example Non Example pada Materi Perilaku Taat Hukum di Kelas X9 SMA N 14 Semarang
Authors: Chasanah Lina Yuliatul , Haryati Titik , Kusumoningsih Dwi
Published: July 2024

Pendidikan merupakan fondasi penting bagi kemajuan bangsa, dimana individu dapat mengembangkan potensinya dan berkontribusi dalam pembangunan. Era globalisasi membawa perubahan pada sistem Pendidikan termasuk model pembelajaran. salah satu alternatif yang dapat digunakan adalah model example non example.  Dalam penelitian ini dideskripsikan tentang implementasi model pembelajaran example non example. Fokus penelitian ini adalah untuk mengetahui seberapa efektif penggunaan model pembelajaran example non example dalam meningkatkan kemampuan pemahaman siswa di kelas X9 SMA Negeri 14 Semarang pada materi perilaku taat hukum. Penelitian ini menerapkan pendekatan kualitatif deskriptif. Penelitian ini mengumpulkan informasi dengan menggunakan data melalui observasi, wawancara, dan dokumentasi. Hasil dari penelitian menunjukkan bahwa dengan menggunakan model pembelajaran example non example dapat membantu siswa memahami materi perilaku taat hukum. Hasil kemampuan memahami dibuktikan oleh nilai siswa, yang rata-rata 89 dari banyak siswa di kelas X9, termasuk 33 siswa, dan 88,5% siswa telah memahami materi dengan baik. Selain meningkatkan pemahaman peserta didik pada materi perilaku taat hukum, implementasi model pembelajaran example non example mendorong peserta didik untuk bernalar kritis, efektif, dan bekerja sama juga meningkatkan hasrat untuk belajar. Akan tetapi, model pembelajaran example non example mempunyai beberapa kelemahan seperti, Tidak semua konten dapat disajikan menggunakan media visual dan membutuhkan waktu yang cukup lama.
Calopepla leayana (Coleoptera :Chrysomelidae) – A pest of Gmelina arborea from
Jharkhand with emphasis on its Biology and Control
Authors: Keshari Seema
Published: July 2024

Calopepla leayana (Coleoptera :Chrysomelidae) is a major pest of Gmelina arborea from Jharkhand. A detailed study on the bionomics was done during the period of two years in 2021-2023 and under control measures in laboratory conditions. The pest is active from march-April to November-December. The beetles feed by cutting circular holes on leaves,destroy young buds of the developing shoots which causes negative effect on growth of the plant and sometimes the trees dry up when severe infestation is seen.
HUBUNGAN PENGETAHUAN DENGAN KETERATURAN PRETANAL YOGA PADA IBU HAMIL TRIMESTER III
Authors: Rufaindah Ervin
Published: July 2024

Many prenatal yoga classes are now facilitated by programs from Community Health Centers, but there are still many pregnant women who have not taken advantage of prenatal yoga classes because there are still many pregnant women who do not understand the importance of prenatal yoga. The aim of this research is to analyze the relationship between knowledge and the regularity of prenatal yoga in third trimester pregnant women. The method in this research is observational analytic with a cross-sectional approach. The population and sample amounted to 30 respondents using total sampling techniques. Research data was obtained through a questionnaire on the knowledge and regularity of prenatal yoga for third trimester pregnant women, then analyzed using the Chi Square test. The results of statistical tests using chi square showed that knowledge was related to the regularity of prenatal yoga with a P value (p) <(0.05). Conclusions and suggestions: The conclusion of this study is that there is a relationship between knowledge and regularity of prenatal yoga for pregnant women in the third trimester. It is recommended for pregnant women to always increase their knowledge through counseling by midwives and other media so that they can increase the regularity of prenatal yoga so that they can directly feel the benefits of prenatal yoga and can have a healthy and happy pregnancy.
PEMBELAJARAN PAI DENGAN PENDEKATAN HUMANISTIK DALAM KURIKULUM MERDEKA
Authors: Okvani Kartika Resti , Nabih Billah Ahmad , Muqowim Muqowim
Published: July 2024

Artikel ini mendiskusikan penerapan pembelajaran PAI dengan pendekatan humanistik dalam kurikulum merdeka. Fakta menunjukkan perkembangan teknologi yang terjadi memberikan pengaruh negatif bagi pendidikan karakter serta menyebabkan penurunan sikap kemanusiaan sehingga diperlukannya pendekatan pembelajaran yang tepat.  Pendekatan humanistik menjadi landasan utama dalam meningkatkan nilai kemanusiaan untuk menanggulangi problematika penurunan moral peserta didik. Oleh karena itu, peneliti menggunakan metode penelitian pustaka (Library Research) dengan teknik analisis isi (content analysis). Hasil penelitian ini menemukan bahwa pembelajaran PAI, pendekatan humanistik dan kurikulum merdeka memiliki keselarasan dalam mencapai tujuan untuk membentuk karakter peserta didik dengan kebebasan yang berlandaskan dengan kemanusiaan. Sehingga guru PAI dapat mengkolaborasikan antara pendekatan humanistik, pembelajaran PAI dan kurikulum merdeka untuk mencapai keberhasilan dalam pembentukan karakter peserta didik. Hasil penelitian ini meskipun masih sederhana dapat dijadikan rujukan guru untuk memilih pendekatan yang sesuai dengan pembelajaran dan kurikulum yang berlaku.
BUDAYA ORGANISASI DAN INOVASI PELAYANAN TERHADAP EFEKTIFITAS PELAYANAN DI MALL PELAYANAN PUBLIK KABUPATEN MAROS
Authors: Sukawati Herlina , Widyawati Widyawati , Sulmiah Sulmiah
Published: July 2024

Kehadiran Mall Pelayanan Publik sebagai langkah pemerintah daerah dalam memunculkan sistem layanan baru dan beradaptasi dengan tuntutan masyarakat, tidak sepenuhnya berhasil memberikan pelayanan yang berkualitas kepada masyarakat. Adanya rasa takut akan kegagalan, kurangnya insetif untuk berinovasi, kurangnya pengembangan dan pembelajaran pegawai dalam peningkatan kinerja, serta kurangnya pemahaman pegawai terhadap program pelayanan, menjadi masalah utama dalam penyelenggaraan pelayanan di Mall Pelayanan Publik. Masalah tersebut terindikasi terjadi pada aspek organisasinya, sehingga penelitian ini dilakukan untuk mengetahui pengaruh budaya organisasi dan inovasi pelayanan publik terhadap efektifitas pelayanan publik di Mall Pelayanan Publik Kabupaten Maros. Agar peneliti mudah untuk menemukan besaran pengaruh budaya organisasi dan inovasi pelayanan terhadap efektifitas pelayanan publik, maka digunakan metode penelitian kuantitatif. Sampel pada penelitian ini berjumlah 98 orang. Data yang bersumber dari penyebaran angket dianalisis menggunakan aplikasi SmartPLS 4.0. Hasil analisis menunjukkan efektivitas pelayanan publik di Mall Pelayanan Publik Kabupaten Maros dominan dipengaruhi oleh budaya organisasi. Pengaruh yang diberikan sebesar 14,9%. Inovasi Pelayanan Publik tidak memberikan pengaruh terhadap peningkatan efektivitas pelayanan di Mall Pelayanan Publik Kabupaten Maros. Secara bersama-sama budaya organisasi dan inovasi pelayanan tidak mempengaruhi efektivitas pelayanan publik. Sebagai variabel dominan dalam penelitian, budaya organisasi juga mempengaruhi pelaksanaan inovasi pelayanan di Mall Pelayanan Publik Kabupaten Maros sebesar 41,6%. Pemerintah Kabupaten Maros dalam memaksimalkan peran Mall Pelayanan Publik dalam meningkatkan kualitas pelayanan publik, perlu untuk memaksimalkan inovasi strategi dan inovasi governance, sebab budaya organisasi yang kuat perlu pula didukung oleh strategi pencapaian dan manajemen pengelolaan, untuk mencapai misi peningkatan efektivitas pelayanan publik di Kabupaten Maros.
MENDORONG PERTUMBUHAN EKONOMI LOKAL: PENDEKATAN DEBIROKRATISASI UNTUK PENGEMBANGAN UMKM DI KOTA BAUBAU
Authors: Ade Saputra Irwan , Purna Zarni Adia
Published: July 2024

Penelitian ini bertujuan untuk melihat pola debiroratisasi dalam kegiatan yang dilakukan pemerintah untuk mendukung UMKM. Metode penelitian yang gunakan adalah jenis penelitian kualitatif dengan tipe eksploratif. Temuan menunjukkan bahwa langkah-langkah debirokratisasi, seperti pemanfaatan platform digital untuk memberdayakan komunitas kreatif, penyederhanaan proses administratif dalam penyediaan dukungan modal dan pelatihan, serta penerbitan kebijakan yang mendukung pengembangan UMKM, telah meningkatkan aksesibilitas dan responsivitas layanan bagi UMKM. Meskipun demikian, masih terdapat kendala struktural dalam ekosistem UMKM yang mempengaruhi pertumbuhannya, seperti akses terhadap modal dan infrastruktur yang terbatas. Selain itu, implementasi kebijakan dan program-program pendukung UMKM masih belum optimal, menyebabkan keterbatasan kontribusi UMKM terhadap PDRB. Penelitian selanjutnya disarankan untuk lebih mendalami faktor-faktor struktural yang mempengaruhi pertumbuhan UMKM, seperti akses terhadap modal dan infrastruktur, serta melakukan evaluasi lebih lanjut terhadap implementasi kebijakan dan program-program yang mendukung UMKM dengan mempertimbangkan faktor-faktor administratif dan institusional yang memengaruhi efektivitasnya.
Family environment supporting radicalization as a mediator in the process of radicalization of adolescents (dataset)
Authors: Hovanová Magdaléna , Lovašová Soňa
Published: July 2024

The family is traditionally perceived as an important factor in the field of radicalization among adolescents, similarly to other pathological phenomena in this target group. If the family professes pathological values but is functioning and the relationships in it are good, adolescents may uncritically accept the opinions of parents and relatives, which may influence their direction towards radicalization. The article brings new knowledge about the role played by the family environment supporting radicalization in families in the process of radicalization of adolescents, where protective factors such as positive relations between adolescents and parents and effective spending of free time with parents are identified. Two mediating models of radicalization were presented in the study, including personal and general values and beliefs in the field of radicalization. The factor Support for radicalization, reflecting the radical environment in the family, acted as a mediator in the model. Independent variables were family factors Free time, CANs, Trust, Norms, Positive relations with parents. In the area of radicalization of personal value, the influence of children's trust towards their parents in a negative direction was shown to be statistically significant. In the field of general values, all investigated independent variables gained significance in a positive direction (except for CAN). When accounting for the mediating effect of a radical family environment, effects in every single variable increased for the factor of general values and beliefs (vs. personal values). For the field of helping professions, this may indicate that, despite the family environment that supports radicalization, there is room for influencing adolescents at the level of personal values and beliefs.
On Defining Typology of the Relationships between Philosophy and Theatre
Authors: Tomáš Hájek Dr. Mgr. MUDr. 
Published: July 2024

Psychology, clinical psychology, psychiatry, as well as neurosciences have produced scientific findings suggesting that theatricality is an essential parameter of the social reality and a person’s navigation in this space.
A Debate on the Use of Gene Therapy in Patients with Haemophilia
Authors: Thornber Katrina
Published: July 2024

GENE therapy is an innovative approach to treating haemophilia A and haemophilia B, with the potential to increase quality of life, promote prophylaxis, and even achieve curative factor levels in some cases. Despite early success in recent clinical trials, gene therapy for treating haemophilia is a relatively new area of research, and the long-term safety and efficacy are yet to be determined. Additionally, the current high price limits access for most patients. The suitability, safety, and accessibility of gene therapy for patients with haemophilia were discussed during a highly engaging debate session at the European Haematology Association (EHA) Congress 2024, titled ‘Haemophilia: Gene Therapy Access for Patients?’.
Darmstadt Open Test Case: Experimental investigation of forced response phenomena in a transonic compressor stage
Authors: Klausmann Fabian Sebastian , Kilian Nicklas , Radermacher Benedikt , Spieker Daniel , Schiffer Heinz-Peter
Published: July 2024

The modular compressor at the Transonic Compressor Darmstadt test facility at Technical University of Darmstadt enables investigations of prototype BLISK rotors in single or 1.5-stage setups, operating at high-speed conditions. Within the framework of the European funded research project ARiAS (Advanced Research into Aeromechanical Solutions), forced response blade vibration phenomena and underlying fluid-structure-interaction are investigated. For this, the Darmstadt Open Test Case is enhanced with new rig hardware and equipped with additional steady and unsteady instrumentation to perform extensive aerodynamic and aeromechanical tests. To excite a distinct engine order, a variable wake generator module is applied upstream the rotor BLISK containing 3–16 equally spaced symmetric NACA airfoils. One goal is to experimentally characterize the resulting flow features and determine the impact of wake forcing and rotor tip-clearance on blade vibration and aero-damping by performing a parameter study of various configurations and operating conditions. This paper comprises an overview of the ARiAS compressor stage setup, applied instrumentation and performed measurements. It emphasizes the substantial aerodynamic variations induced by different excitation features, while simultaneously highlighting the inherent independence of the measured system damping from these variations across three fundamental resonance crossings.
Thermodynamic performance study of simplified precooled engine cycle with coupling power output
Authors: Wang Yifan , Liu Dechen , Xu Pengcheng , Du Pengcheng , Zou Zhengping
Published: July 2024

Horizontal takeoff and landing, reusable hypersonic vehicles have become one of hot spots of aviation field due to their high performance over all operating conditions. The propulsion system with high performance power output capability inside flight envelope is the key to conduct various missions. In order to meet the power demand of the vehicle systems, a coupled power output moderate pre-cooled cycle engine thermodynamic cycle based on closed-cycle supercritical helium was established. The sensitivity of propulsion system parameters and the overall performance of the design point of the thermodynamic cycle were analyzed. The influence law of the power extraction parameters was comparatively analyzed between the bleeding of high-pressure pre-combustion gas and expansion power from supercritical helium closed-cycle. According to the above results, a moderate precooled engine based on supercritical helium closed-cycle with power extraction was constructed. The results show that the scheme can achieve the performance of 109.6 kN thrust and 1,645 s specific impulse with 2 MW power extraction at 25.8 km, Ma5.0, which could provide a new idea for precooled engine scheme with power output.
Upper Arm Exercises on Pain Intensity Among Patient with Breast Cancer Dharmais Cancer Hospital, Indonesia
Authors: Damayanti Sri Utami , Nursanti Irna , Irawati Diana , Natashia Dhea , Herawati Eva
Published: July 2024

Aim: to determine the effectiveness of upper arm exercises on pain intensity among patients with breast cancer at the Dharmais Cancer Hospital, Indonesia.
Methods: This study used a queasy experiment with pre-post-test and two-group design. Twenty respondents from breast cancer patients in each intervention and control group were recruited. The upper arm training intervention was carried out 3 times/week for 3 weeks. The Visual Analogue Scale (VAS) was used to assess pain, and linear regression and the dependent t-test with a significance level of 0.05 (CI 95%) were used for analysis.
Result: The significant difference in pain levels between the intervention group and the control group shows that the mean difference in the pain level scale of respondents in the upper arm exercise intervention group was 2.50 (SD=0.60), while in the control group, the mean was 1.70 (SD=0.65). control group with (t=4.00, p=0.001), and age (p-value =0.023; OR=8.645) were predictors in this study.
Conclusions: Upper arm exercises can be recommended to reduce pain in breast cancer sufferers, especially breast cancer patients who have undergone stage 1 and 2 mastectomy operations. It is recommended that further research involve respondents who had the same level of pain before upper arm exercises were carried out
Effect of Range of Motion Exercise on Extremity Joint Muscle Strength in Ischemic Stroke Patients a Literature review
Authors: Nasim Nasim , Nani Desiyani
Published: July 2024

Aims: Muscle strength and Range of Motion (ROM) are very important for ischemic stroke patients because they can prevent contractures, and increase the muscle strength of ischemic stroke patients. Range of motion (ROM) exercises in the upper extremities can increase muscle strength so that post-stroke patients can perform Activities of Daily Living independently. Objective: To know about the effect of the effectiveness of ROM with various methods to increase muscle strength and range of motion of joints.
Method: Literature review to determine range of motion exercise on limb joint muscle strength in ischemic stroke patients with 5 articles with 4 data  search tools: PubMed, NCBI, Science Direct, and Proquest. The inclusion criteria were patients who had an ischemic stroke, randomized control trials, and the full text available in a literature review published in the last five years, i.e. 2018-2023, articles in English.
Results: From the articles obtained, 556 articles were found  Research campresearch searched in accordance with creteria found 5 articles on the effect of range of motion exercise on muscle strength of the extremity joints in ischemic stroke patients.  Positive results were obtained from the benefits of muscle strength and ROM. Clinical evidence was obtained from five journals analyzed that there was an increase in strength and range of motion and there were differences in the results of the experimental group and the control group.
Conclusion: The provision of ROM intervention techniques is proven to increase muscle strength and joint range of motion in ischemic stroke patients, so as to help patients in the process of maintaining muscle strength and joint range of motion. In the future, this activity can be done independently by patients at home.
Cognitive Behaviour Therapy with Roy Adaptation Approach on Improving Adolescent Self-Esteem in the Special Institution for Children Class I Martapura
Authors: Sitanggang Yohana Agustina , Lani Tiara , Raziansyah Raziansyah
Published: July 2024

Aims: This research aims to examine the impact of cognitive behaviour therapy with Roy's adaptation approach on increasing adolescent self-esteem in the Special Development Institute for Children Class 1 Martapura.
Methods: This research employed a Quasi-Experimental Pre-Post Test with Control Group design. The sample size consisted of 30 respondents, divided into 15 in the treatment group and 15 in the control group, selected using purposive sampling techniques. The research instrument utilized to measure self-esteem was the Rosenberg Self-Esteem Scale.
Results: The outcomes revealed a significant increase in adolescent self-esteem before and after receiving cognitive behavior therapy with the Roy adaptation approach in the treatment group, with a p-value of 0.014 < 0.05. This indicates that there is a positive effect of administering cognitive behavior therapy with the Roy adaptation approach on adolescent self-esteem at the Class 1 Martapura Children's Special Development Institute. Conversely, the control group experienced a decline in self-esteem during the post-test measurement.
Conclusion: Cognitive Behaviour Therapy with Roy's adaptation theory approach conducted in 3 sessions is able to improve the self-esteem of adolescents who are in the Class 1 Martapura Children's Special Development Institute.
Assessing the Impact of Visual Educational Interventions on User Adoption of Electronic Medical Records in the Inpatient Ward of RSUD Dr. Soeselo, Tegal Regency
Authors: Prihati Eko , Arso Septo Pawelas , Agushybana Farid
Published: July 2024

Aims: Electronic medical records (EMRs) are information systems used to store and manage patients' medical information electronically. Despite being a well-established technology, their implementation often faces resistance, particularly in terms of users' readiness to adapt to new technologies. This study aims to evaluate the acceptance of EMRs among healthcare professionals in the inpatient installation of RSUD Tegal.
Methods: The study employed a Quantitative Pre-Experimental method with a One group Pre-test Post-test experimental design. It assessed changes or differences in user acceptance by examining attitudes and behavioral intentions of users before and after learning through video-based instruction. Pre-test and post-test questionnaires were used for data collection.
Results: Data analysis revealed an Asymp.Sig. value of 0.000, which is less than 0.05. This indicates that Ho (the null hypothesis) is rejected, suggesting a difference in the average results of the Pre-test on the six variables related to user acceptance of EMRs. Similarly, the Friedman Test Post-test yielded an Asymp. Sig. value of 0.000, also less than 0.05. This further supports the rejection of Ho, indicating a difference in the average results of the six variables. Additionally, the influence of video-based learning on behavioral intentions to use EMRs was determined with a Wilcoxon Signed Ranks Test, resulting in an Asymp.sig (2-tailed) value of 0.000.
Conclusion: The study found that there is an increase in behavioral intentions to use EMRs after learning through video-based methods.
Factors Influencing Toddler Visit to Integrated Healthcare Center in Sukabumi District
Authors: Pratiwi Kusuma Putri
Published: July 2024

Aims: The purpose of this study was to determine the effect of knowledge, motivation, the role of health workers, and family support on toddler visit to integrated healthcare center in Sukabumi district.
Methods:  This type of research was conducted with a cross sectional design. The population was all mothers of toddlers with a sample of 225, using proportional random sampling technique. Statistical analysis to determine the effect using logistic regression.
Results:  There is an influence of knowledge (p=0.000), motivation (p=0.000), the role of health workers (p=0.000) and family support (p=0.000) on toddler posyandu visits in Sukamanis Village, Kadudampit Health Center Working Area, Sukabumi Regency.
Conclusion:  Knowledge, motivation, role of health workers and family support influenced toddler posyandu visits in Sukamanis Village, Kadudampit Health Center Working Area, Sukabumi District.
History of Types and Length of Contraceptive Methods Use with Pre-Menopausal Complaints in Pre-Menopausal Women
Authors: Aisyatul R. Hana , Yudianti Ika , Mas’udah Endah Kamila
Published: July 2024

Menopausal events are associated with decreased production of reproductive hormones, namely progesterone and estrogen. Both hormones in synthetic form are also present in some types of hormonal contraceptive methods. This study aims to determine the relationship between the history of the type of method and the length of use of contraceptives with the intensity of menopausal complaints. The design used is correlational analytics with a cross-sectional approach. A sample of 174 premenopausal women was selected by proportional random sampling. Information on the type and duration of contraceptive use was taken through interviews, and the intensity of premenopausal complaints was measured using the MRS (Menopause Rating Scale) questionnaire. Data analysis using regression methods was performed with STATA Statistics version 12.0, with statistical significance set at P < 0.05. Data analysis showed the associations between contraceptive types and pre-menopausal complaints (p-value 0.025) and between the length of contraceptive use and pre-menopausal complaints (p-value 0.021). The study recommends that contraceptive users consider the type and length of their methods, and healthcare providers should offer detailed counseling on how contraceptive choices might affect pre-menopausal symptoms. Future research should continue exploring the connection between contraceptive use and pre-menopausal complaints for more tailored guidance in the choice of contraceptive methods.
Health Adaptation Behavior of Farmers and Fishermen in Areas Exposed to Climate Change
Authors: Riviwanto Muchsin , Barlian Eri , Dwiyanti Defriani
Published: July 2024

Climate change is a definite, indisputable, clear, firm, and imminent reality, and has the potential to become a serious threat and challenge for the agriculture and fisheries sector. Climate change not only has an impact on the economy but also the health of farmers and fishermen. Farmers and fishermen must have health adaptation behavior to anticipate the adverse effects of climate change. This study aims to look at the individual's adaptive behavior and the factors that influence it. This study uses a cross sectional design on the heads of families of farmers and fishermen affected by climate change in the Province of West Sumatra, Indonesia. The number of samples as many as 150 samples were taken by probability proportional to size (PPS). Collecting data using primary data with interviews method. Data processed by computer and multivariate analysis with logistic regression testThe results of this study found the influence of husband's education, family income, self-efficacy, self-awareness, attitudes, perceptions, life skills, health care support, access to information about climate change together on health adaptation behavior. The most important determinants of health adaptation behavior are husband's education and self-awareness. There is a need for non-formal education in the form of socialization and training on adaptation of public health in the face of climate change. The government must integrate health and climate programs, climate socialization for health workers and provide compensation for people exposed to climate change.
Analysis Factor Dominance and Contribution Program Performance against Stunting Incidents in Bali Province: SSGI Data Analysis
Authors: Suiraoka I Putu , Nursanyoto Hertog , Suarjana I Made , Suastiti Ni Made Ayu
Published: July 2024

Since 2017, Bali Province has consistently ranked first in the lowest stunting prevalence in Indonesia. Planned programmes should be exploring and identifying certain factors which trigger stuntling, so as to reduce the prevalence of stuntin' at least in line with established distribution patterns. The data used in this research is secondary data from the Indonesian Nutrition Status Study in the Province. The analysis carried out included: Univariate analysis and multivariate analysis using backward logistic regression analysis. The results of the analysis of determinant factors and performance evaluation of the Nutrition and Health Program in Bali Province show that the factors that contribute to the stunting problem in Bali are: (a) area of residence (AOR= 1.57; 95%CI= 1.31 - 1.89); (b) PMT for pregnant women (AOR= 0.55; 95% CI= 0.39 - 0.78); (c) Pregnancy Examination (AOR= 0.83; 95%CI= 0.61 - 1.14); (d) Birth Status (AOR= 1.52; 95%CI= 1.22 - 1.90); (e) Body length at birth (AOR= 1.54 - 2.11); (f) Birth weight (AOR= 2.48; 95%CI= 1.71 - 3.58); (g) Variety of Toddler Consumption (AOR= 1.65; 95%CI= 1.36 - 2.00); and (h) Program Immunization (AOR=.0.69; 95%CI= 0.51 - 0.96). The potential for stunting occurs before the baby is born; therefore, it is recommended that priority programs be developed for women of childbearing age and pregnant women
The roles of FHL2 as a mechanotransducer for cellular functions in the mechanical environment
Authors: Fujimoto Yukari , Nakazawa Naotaka
Published: July 2024

The cell has multiple mechanisms for sensing and responding to dynamic changes in the mechanical environment. In the process, intracellular signaling is activated to modulate gene expression. Recent studies have shown that multifunctional signaling molecules that link intracellular force and gene expression are important for understanding cellular functions in the mechanical environment. This review discusses recent studies on one of the mechanotransducers, Four-and-a-half LIM domains 2 (FHL2), which localizes to focal adhesions (FAs), actin cytoskeleton, and nucleus. FHL2 localizes to FAs and the actin cytoskeleton in the cell on stiff substrate. In this situation, intracellular tension of F-actin by Myosin II is critical for FHL2 localization to FAs and actin stress fibers. In the case, a conserved phenylalanine in each LIM domain is responsible for its localization to F-actin. On the other hand, lower tension of F-actin in the cell on a soft substrate causes FHL2 to be released into the cytoplasm, resulting in its localization in the nucleus. At the molecular level, phosphorylation of specific tyrosine in FHL2 by FAK, non-receptor tyrosine kinase, is critical to nuclear localization. Finally, by binding to transcription factors, FHL2 modulates gene expression for cell proliferation as a transcriptional co-factor. Thus, FHL2 is involved in mechano-sensing and -transduction in the cell in a mechanical environment.
Hemichannels contribute to mitochondrial Ca2+ and morphology alterations evoked by ethanol in astrocytes
Authors: Alvear Tanhia F. , Farias-Pasten Arantza , Vergara Sergio A. , Prieto-Villalobos Juan , Silva-Contreras Antonia , Fuenzalida Fernando A. , Quintanilla Rodrigo A. , Orellana Juan A.
Published: July 2024

Alcohol, a toxic and psychoactive substance with addictive properties, severely impacts life quality, leading to significant health, societal, and economic consequences. Its rapid passage across the blood-brain barrier directly affects different brain cells, including astrocytes. Our recent findings revealed the involvement of pannexin-1 (Panx1) and connexin-43 (Cx43) hemichannels in ethanol-induced astrocyte dysfunction and death. However, whether ethanol influences mitochondrial function and morphology in astrocytes, and the potential role of hemichannels in this process remains poorly understood. Here, we found that ethanol reduced basal mitochondrial Ca2+ but exacerbated thapsigargin-induced mitochondrial Ca2+ dynamics in a concentration-dependent manner, as evidenced by Rhod-2 time-lapse recordings. Similarly, ethanol-treated astrocytes displayed increased mitochondrial superoxide production, as indicated by MitoSox labeling. These effects coincided with reduced mitochondrial membrane potential and increased mitochondrial fragmentation, as determined by MitoRed CMXRos and MitoGreen quantification, respectively. Crucially, inhibiting both Cx43 and Panx1 hemichannels effectively prevented all ethanol-induced mitochondrial abnormalities in astrocytes. We speculate that exacerbated hemichannel activity evoked by ethanol may impair intracellular Ca2+ homeostasis, stressing mitochondrial Ca2+ with potentially damaging consequences for mitochondrial fusion and fission dynamics and astroglial bioenergetics.
2D/2D Bi2Se3/SnSe2 heterostructure with rapid NO2 gas detection
Authors: Yi Shuangshuang , Chen Cunguang , Yu Meiling , Hao Juanjuan , Wang You
Published: July 2024

Heterostructure engineering is crucial for enhancing gas sensing performance. However, achieving rapid response for room-temperature NO2 sensing through rational heterostructure design remains a challenge. In this study, a Bi2Se3/SnSe2 2D/2D heterostructure was synthesized by hydrothermal method for the rapid detection of NO2 at room temperature. By combining Bi2Se3 nanosheets with SnSe2 nanosheets, the Bi2Se3/SnSe2 sensor demonstrated and the lowest detection limit for NO2 a short response time (15 s) to 10 ppm NO2 at room temperature, reaches 25 ppb. Furthermore the sensor demonstrates significantly larger response to NO2 than to other interfering gases, including 10 ppm NO2, H2S, NH3, CH4, CO, and SO2,demonstrating its outstanding selectivity. And we discuss the mechanism of related performance enhancement.
Efficient In/SSZ-39 catalysts for the selective catalytic reduction of NO with CH4
Authors: An Sufeng , Wang Peng , Wang Kuanling , Wang Xuehai , Li Baozhong , Guo Xinwen
Published: July 2024

The M/SSZ-39 catalysts (M = In, Co, Cu, Fe) with different metal species and metal loadings were synthesized using the wet impregnation method on a small-pore SSZ-39 molecular sieve. X-ray diffraction (XRD), transmission electron microscopy (TEM), nitrogen adsorption-dehydrogenation and hydrogen temperature program reduction (H2-TPR) were employed to characterize the effects of various metal components and metal loadings on the performance of CH4 selective catalytic reduction of NO reaction (CH4-SCR). The characterization results showed that the In/SSZ-39 catalyst exhibited significantly higher catalytic activity compared to the Cu-, Co-, and Fe/SSZ-39 catalysts, suggesting that indium (In) is a more suitable active ingredient for the CH4-SCR reaction. The xIn/SSZ-39 (x = 1, 2, 3, x represents the In loadings of 1.0 wt%, 2.0 wt% and 3.0 wt%) catalysts, with different In loadings, all present excellent CH4-SCR performance. By varying the In loadings, the type of In species present in the catalyst can be regulated, thus enhancing DeNOx activity and CH4 selectivity in the CH4-SCR reaction. At a low temperature of 400 °C and a low CH4/NO feed ratio (CH4/NO = 1), the 3In/SSZ-39 catalyst, featuring highly active InOx clusters, achieves the best low-temperature CH4-SCR performance, with a high NO conversion rate of up to 90% and a CH4 selectivity of up to 74.2%.
Cybersecurity for Industry 5.0: trends and gaps
Authors: Kour Ravdeep , Karim Ramin , Dersin Pierre , Venkatesh Naveen
Published: July 2024

Industry 5.0 promises to revolutionize the industry by focusing on human-centric, sustainability, and resilience empowered by emerging technologies such as Artificial Intelligence (AI) and digitalization. This paradigm shift is expected to bring significant advancements in sustainability, resilience, productivity, effectiveness, efficiency, customization, reliability, safety, security, maintainability etc. However, this shift of the industrial paradigm introduces substantial cybersecurity challenges due to the increased attack surface and data sensitivity. Therefore, the objective of this paper is to conduct a thorough literature review of the recent research on cybersecurity in Industry 5.0, highlighting emerging trends, gaps, and potential solutions. To conduct this research, the authors have applied the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology to investigate cybersecurity solutions in Industry 5.0. The findings reveal that conceptual research dominates, with AI, Blockchain, and Internet of Things (IoT) most prevalent but highlights a gap in linking cybersecurity to resilience and sustainability. Furthermore, the paper aims to present trends in cybersecurity research with more relevant results from 2022 to 2024. It conducts a thorough review of the literature, highlighting the evolving landscape of cybersecurity applications in Industry 5.0.
Uranium resources associated with phosphoric acid production and water desalination in Saudi Arabia
Authors: Ud-Din Khan Salah , Ahmad Ashfaq , Khan Rawaiz , Haneklaus Nils
Published: July 2024

Due to the rising demand for energy and the imperative to achieve net-zero carbon emissions, there is a growing focus on nuclear energy for its high efficiency as a clean energy source with minimal direct greenhouse gas emissions. The Kingdom of Saudi Arabia has set forth ambitious plans to construct multiple nuclear power plants in the near future. It is worth noting that phosphate rocks and desalination concentrate both contain relevant concentrations of naturally occurring uranium, presenting potential domestic uranium sources for the envisaged nuclear reactor fleet. This study offers a first systematic overview of the potential quantities of uranium that could theoretically be recovered during seawater desalination and phosphoric acid production in Saudi Arabia using best available technologies. It was found that in 2021 approximately 447–596 t natural uranium could have theoretically been recovered during phosphoric acid production in the Kingdom of Saudi Arabia. In addition, there were also 6.5 t uranium associated with seawater that was desalinated in 2021. If recovered the amounts would theoretically be able to provide 12%–16% (uranium from phosphoric acid) and 0.2% (uranium from seawater desalination) of the annual uranium requirements of the projected Saudi nuclear power plant fleet in 2040. As a result, we strongly recommend fostering research on unconventional uranium recovery during phosphoric acid production by promoting public-private partnerships that have the potential to develop industrial scale solutions.
A practical nomogram for preoperatively predicting lateral cervical lymph node metastasis in medullary thyroid carcinoma: a dual-center retrospective study
Authors: Zhu Jialin , Guo Tiantian , Guo Shuyue , Chang Luchen , Zhao Jing , Wang Xiaoqing , Wei Xi
Published: July 2024

Purpose

Lateral lymph node metastasis (LLNM) is very common in medullary thyroid carcinoma (MTC), but there is still controversy about how to manage cervical lateral lymph nodes, especially for clinically negative MTC. The aim of this study is to develop and validate a nomogram for predicting LLNM risk in MTC.

Materials and methods

A total of 234 patients from two hospitals were retrospectively enrolled in this study and divided into LLNM positive group and LLNM negative group based on the pathology. The correlation between LLNM and preoperative clinical and ultrasound variables were evaluated by univariable and multivariable logistic regression analysis. A nomogram was generated to predict the risk of the LLNM of MTC patients, validated by external dataset, and evaluated in terms of discrimination, calibration, and clinical usefulness.

Results

The training, internal, and external validation datasets included 152, 51, and 31 MTC patients, respectively. According to the multivariable logistic regression analysis, gender (male), relationship to thyroid capsule and serum calcitonin were independently associated with LLNM in the training dataset. The predictive nomogram model developed with the aforementioned variables showed favorable performance in estimating risk of LLNM, with the area under the ROC curve (AUC) of 0.826 in the training dataset, 0.816 in the internal validation dataset, and 0.846 in the external validation dataset.

Conclusion

We developed and validated a model named MTC nomogram, utilizing available preoperative variables to predict the probability of LLNM in patients with MTC. This nomogram will be of great value for guiding the clinical diagnosis and treatment process of MTC patients.
Cord blood vitamin A and vitamin D levels in relation to physical growth in exclusively breastfed infants aged 0-6 months
Authors: Zhao Wei , Li Chao , Shen Wen Zhi , Li Kai Yun , Cai Yi Xi , Li Feng , Fu Hong , Peng Bin , Chen Jie , Li Ting Yu , Chen Li
Published: July 2024

Background

Vitamins A and D are essential for the health of pregnant women and infants. Nevertheless, the relationship between umbilical cord blood vitamins A and D levels and the physical growth of exclusively breastfed infants remains uncertain.

Objective

This cohort study aims to examine the relationship between cord blood vitamins A and D levels and the physical growth of exclusively breastfed infants aged 0–6 months.

Methods

140 singleton mother–infant pairs were recruited in total. Questionnaires were used to collect maternal and infant information, and liquid chromatography was utilized to quantify the levels of vitamins A and D in the umbilical cord blood. Anthropometric measurements were conducted at birth, at 3 and 6 months of age, and the weight-for-age z-score (WAZ), length-for-age z-score (LAZ), head circumference-for-age z-score (HAZ), and BMI-for-age z-score (BMIZ) were calculated. Univariate and multivariate linear regression models were used for the analysis.

Results

The average concentration of vitamins A and D in cord blood was 0.58 ± 0.20 μmol/L and 34.07 ± 13.35 nmol/L, both below the normal range for children. After adjusting for confounding factors, vitamin A levels in cord blood positively correlated with HAZ growth in infants aged 3–6 months (β= 0.75, P < 0.01) while vitamin D levels negatively correlated with LAZ growth (β= −0.01, P = 0.01) and positively correlated with BMIZ growth (β= 0.02, P < 0.01).

Conclusion

Higher Vitamin A levels at birth promote HAZ growth in infants aged 3–6 months while higher vitamin D levels at birth promote BMIZ growth in infants aged 3–6 months.

Clinical trial registration

https://register.clinicaltrials.gov, identifier NCT04017286.
Association between ankle-brachial blood pressure index and erectile dysfunction in US adults: a large population-based cross-sectional study
Authors: Wu Xu , Zhang Yuyang , Zheng Xuejie
Published: July 2024

Background

Erectile dysfunction (ED) is a very common condition among adult men and its prevalence increases with age. The ankle-brachial blood pressure index (ABPI) is a noninvasive tool used to assess peripheral vascular disease (PAD) and vascular stiffness. However, the association between ABPI and ED is unclear. We aimed to explore the association between ABPI and ED in the US population.

Methods

Our study used data from two separate National Health and Nutrition Examination Survey (NHANES) datasets (2001-2002 and 2003-2004). Survey-weighted logistic regression models were used to explore the association between ABPI as a continuous variable and quartiles with ED. We further assessed the association between ABPI and ED using restricted cubic regression while selecting ABPI thresholds using two-piecewise Cox regression models. In addition, we performed subgroup analyses stratified by BMI, race, marital status, diabetes, and hypertension.

Main outcome measure

ABPI was calculated by dividing the mean systolic blood pressure at the ankle by the mean systolic blood pressure at the arm.

Results

Finally, 2089 participants were enrolled in this study, including 750 (35.90%) ED patients and 1339 (64.10%) participants without ED. After adjusting for all confounding covariates, logistic regression analyses showed a significant association between ABPI and ED (OR=0.19; 95% CI, 0.06-0.56, P=0.01); with ABPI as a categorical variable, compared with the lowest quartile, the OR and 95% CI for the second quartile were 0.58 (0.34-0.97; P = 0.04).Besides, splines indicated that there was an L-shaped relationship between ABPI levels and the risk of ED. Piecewise Cox regression demonstrated the inflection point at 1.14, below which the OR for ED was 0.06 (0.02-0.20; P < 0.001), and above which the OR was 2.79 (0.17-4.53; P = 0.469).

Conclusion

In our study, lower ABPI was independently associated with ED risk. In addition, the lowest ABPI level associated with ED risk was 1.14, below this level, lower ABPI was associated with higher ED risk.
Prospective techno-economic and life cycle assessment: a review across established and emerging carbon capture, storage and utilization (CCS/CCU) technologies
Authors: Wang Pingping , Robinson Ada Josefina , Papadokonstantakis Stavros
Published: July 2024

Carbon Capture, Storage and Utilization (CCS/CCU) is critical for achieving net-zero emissions. Although the recent surge in CCS/CCU projects announcement, there is a clear gap between announced capacity (around 400 Mt CO₂ per year) and the Net Zero Emissions (NZE) scenario deployment target (around 1 Gt per year) by 2030. This review examines breakthroughs and advancements across both established and emerging CCS/CCU systems with different Technology Readiness Levels (TRLs) in various industrial sectors, emphasizing the necessity of prospective assessments for their acceleration and scalability. It examines the development and application of prospective Life Cycle Assessment (pLCA) and prospective Techno-Economic Assessment (pTEA), highlighting their limitations and importance of their outcomes in decision-making processes. Differences between the evolving dynamics of the technological systems (foreground) and the evolution of the overall socioeconomic system (background) are discussed. Incorporating scenario data from Integrated Assessment Models (IAMs) into pLCA and pTEA reveals an iterative relationship that significantly influences the outcome of both the environmental assessments and the economics of large-scale production of the CCS/CCU systems under study. This, in turn, could reshape investment strategies towards advanced technologies, necessitating their consideration within the evolving structure of IAMs. It is concluded that the inherent limitations of CCS/CCU technologies at an early stage of development require quantitative uncertainty analysis and demand robustness, interdisciplinary collaboration, policy intervention, and data transparency. The rigorous evaluative frameworks are key for developing economic, environmental and climate policies and enable well-informed decisions across rapidly evolving sectors. A framework is proposed in this review, outlining a multistep process that includes a series of databases and open-source tools to interface pTEA and pLCA with enhanced IAMs for CCS/CCU, demonstrating its potential to improve decision-making and policy development.