bluuebunny/crossref_metadata_2025 huggingface dataset:
Hydroinformatics in China: overall developments and showcase of accomplishments in the Changjiang River basin
Authors: Huang Y. , Ba H. H. , Yu S.
Published: December 2022

Over the last few decades, China has experienced tremendous growth and socioeconomic development. This has also been a period of significant transformations in many social and economic sectors, including water management. Starting from revision of policies and regulatory frameworks, modifications of water engineering approaches have been introduced, together with broadening the overall management of river basins and water resources to encompass ecological and other nature services, next to considerations for economic benefits. These water management transformations have also been facilitated and enabled by introducing novel information and communication technologies, very much along the lines that Mike Abbott predicted and promoted as he was developing the field of hydroinformatics. In fact, he was always considering China as a country that would greatly benefit from hydroinformatics technologies as it has been going through rapid socioeconomic development, and, that the field itself would then make progress via novel Chinese applications. This chapter briefly introduces the main water management transformations and challenges that China has faced over the past few decades, and proceeds with presentation of hydroinformatics tools and technologies in the sequence of data→models→knowledge→decision-support applications, as they have been deployed in China. To showcase the use of such technologies in actual water management activities, the example of Changjiang River basin is presented as a case study, with demonstration of applications on flood management. These applications integrate monitored data with a suite of different models for flood forecasting and regulation of water infrastructure - particularly large scaled reservoir groups, where flood management is addressed in conjunction with other water resources functions. Decision support applications, such as to enable broader stakeholder and public participation - the platform serving for river/lake chief system - are also presented.
Pressupostos da competência crítica em informação e fundamentos da democracia deliberativa a partir de Jürgen Habermas
Authors: Gerlin Meri Nadia Marques , Nunes Denise Bacellar , Campos Ana Claudia Borges
Published: December 2022

O presente estudo pretende dialogar sobre o conceito contemporâneo da informação como veículo democrático. A informação na contemporaneidade tem sido banalizada, haja vista que ela é um instrumento de poder já que tem a capacidade de se comunicar com o seu meio e, ao mesmo tempo, é usada como estratégia de dominação. A democracia, governo de muitos, busca integrar interesse de todos na tentativa de criar um ambiente equânime de tomada de decisões. De um lado temos a informação e todas as suas nuanças e, do outro, a manipulação dela fundamentada no discurso de que corrobora para o movimento democrático. O tema é fronteiriço, arenoso e recorrente direcionado a seguinte pergunta de investigação: quais são as teorias produzidas no campo da informação que corroboram com o desenvolvimento de habilidades e competências na tomada de decisão democrática? Cabe refletir sobre os fundamentos da democracia deliberativa a partir de Jürgen Habermas dentro do contexto da teoria crítica, trazendo à tona, desse modo, a ideia da competência crítica em informação. Na tentativa de operar e sustentar este estudo, utilizaremos, como inspiração, o autor supracitado, para (re)pensar pressupostos teóricos da Ciência da Informação, e, por conseguinte, buscar responder à questão de investigação que orienta esse processo de investigação dialógico, porém, não se encerrando nela para procurar pensar a competência em informação na sociedade contemporânea.
Notas sobre uma relação entre (des) ocupação do território e uso da informação, em tempos de neoliberalismo
Authors: Loureiro Eugênia Vitória Camera
Published: December 2022

O objetivo deste trabalho é o de examinar processos de exclusão e expulsão que vem se ampliando nos diversos aspectos da vida sob as condições atuais do neoliberalismo e como se manifesta na ocupação/desocupação do território, no papel da informação nesse processo e como as alterações das condições tanto da ocupação da terra quanto de produção e uso da informação impostas podem resultar na expulsão de moradores e na exclusão de usuários. Este trabalho também aponta possibilidades de surgimento de condições alternativas por meio da construção de contraracionalidades na constituição de uma esfera pública política e democrática. Elaborei 7 Notas.
É possível uma distinção entre os conceitos de ilustrar e informar em fotografias?
Authors: Guerra Claudia Bucceroni , Marques Junior Jairo André
Published: December 2022

Esta apresentação deriva do projeto de pesquisa “A dimensão Iconológica segundo Aby Warburg: uma proposta de descrição contextual de fotografias (2020 – 2022)” e tem como principal objetivo traçar caminhos para responder a uma questão que pode contribuir para o desenvolvimento de formas descritivas contextuais: É possível uma distinção entre os conceitos de ilustrar e informar em fotografias? A proposta do artigo é apresentar caminhos para definições desses importantes conceitos para a descrição de fotografias. Baseia-se na leitura de teóricos como Vilém Flusser e André Rouillé.
ordem como vontade e as possibilidades do caos
Authors: Mello Marcelo Pereira de
Published: December 2022

Este trabalho pretende confrontar as concepções teóricas das análises sociológicas tradicionais sobre a “ordem social”, as quais chamaremos de “sensualistas” - por pressuporem uma ordem social naturalizada, com as teorias cognitivistas que veem a “ordem social” como construção teórico-intelectiva dos indivíduos. Nossa expectativa é que essa discussão nos auxilie a entender o contexto atual da emergência de movimentos políticos radicalizados, não importa por qual matiz ideológico, e o risco real e a ameaça potencial que eles representam para a estabilidade dos consensos tácitos assumidos pelos agentes na ordem social, tais como as noções de justo e injusto, certo e errado, bem e mal. Esperamos que a discussão sobre os fundamentos da ordem social, na forma colocada pelos cientistas sociais, se apodícticos e factuais ou cognitivos e racionais, ajude-nos a esclarecer até que ponto o radicalismo político, e os radicalismos de maneira geral, seja religioso, moral, bem como as ameaças de diáspora que os acompanham, têm o potencial de impor revezes ao que alguns analistas costumam chamar de “marcos civilizatórios”. Até que ponto, o extremismo político tem condições de impor perturbações de natureza moral aos pactos sociais ameaçando-os real e massivamente.
Informação no ‘mundo 3’ de popper
Authors: Matos José Claudio
Published: December 2022

Este estudo reflete sobre fundamentos epistemológicos da ciência da informação. Segue métodos compatíveis com a reflexão epistemológica, baseia-se numa pesquisa bibliográfica de autores e temáticas relevantes à construção do argumento. Analisa os trabalhos recuperados mediante a interpretação crítica de suas teses. A hipótese que mobiliza a discussão é a de que a teoria objetiva do conhecimento, da qual resulta a noção de ‘mundo 3’ de Karl Popper, tem consequências relevantes para uma concepção epistemológica da informação e, consequentemente, da ciência da informação. Apresenta uma interpretação do ‘mundo 3’, em sintonia com os fundamentos da ciência da informação, com base no exame das evidências encontradas nas obras do próprio Popper. Trabalhos de autores da ciência da informação que se referem às teorias de Popper são discutidos, a fim de fundamentar a linha interpretativa do argumento. Conclui-se por uma identificação entre o ‘mundo 3’ de Popper e a cultura humana. Disto resulta a noção de um processo evolutivo da informação, no qual a ciência da informação desempenha um papel relevante. Nesta imagem, a ciência da informação teria a função de moldar o ambiente, substituindo a informação desordenada pela informação cultivada e criada para interesses produtivos humanos.
Oscillatory Heat Transfer Due to the Cattaneo-Hristov Model on the Real Lin
Authors: Avci Derya , İskender Eroğlu Beyza Billur
Published: December 2022

This chapter aims to discuss the analytical solutions for heat waves
observed in Cattaneo-Hristov heat conduction modelled with Caputo-Fabrizio
fractional derivative. This operator includes a non-singular exponential kernel and
also requires physically interpretable initial conditions for its Laplace transform
property. These provide significant advantages to obtain analytical solutions. Two
different types of harmonic heat sources are assumed to elicit heat waves. The
analytical solutions are obtained by applying Laplace transform with respect to the
time variable and the exponential Fourier transform with respect to spatial coordinate.
The temperature curves for varying values of the fractional parameter, angular
frequency, and the velocity of the moving heat source are drawn using MATLAB.
A Unified Approach for the Fractional System of Equations Arising in the Biochemical Reaction without Singular Kernel
Authors: Veeresha P. , Kiran M.S. , Akinyemi L. , Yavuz Mehmet
Published: December 2022

The pivotal aim of the present work is to find the solution for the fractional
system of equations arising in the biochemical reaction using q-homotopy analysis
transform method (q-HATM). The hired scheme technique unification of Laplace
transform with q-homotopy analysis method, and fractional derivative defined with
Caputo-Fabrizio (CF) operator. To validate and illustrate the competence of the future
method, we examined the model in terms of fractional order. The fixed-point theorem
hired to demonstrates the existence and uniqueness. Moreover, the physical nature of
achieved solutions has been captured in terms of plots for different order. The
obtained results elucidate that the considered algorithm is easy to implement, highly
methodical, and very effective as well as accurate to analyse the nature of nonlinear
differential equations of fractional order arising in the connected areas of science and
engineering.
influence of brand awareness and sales promotion on purchase decisions of OVO products
Authors: Mutiansyah Muhammad Fadli , Wahab Zakaria , Isnurhadi Isnurhadi , Widiyanti Marlina
Published: December 2022

This study aimed to analyze the role of brand awareness and sales promotion in purchasing decisions for OVO products among students of the Faculty of Economics, Master of Management Study Program, Sriwijaya University. The population in this study were students of the Master of Management study program at Sriwijaya University, with the sample used being Master of Management students with a minimum of 1 transaction using OVO. The analysis technique in this study used multiple linear regression analysis by adding the tt-test and F-test as support. The results of this study are that both Brand Awareness and Sales Promotion significantly and simultaneously influence the decision to buy OVO products.
Studi Evaluasi Kebutuhan Air Irigasi dan Penyusunan Jadwal Pembagian Air pada Daerah Irigasi Kedungrejo Kabupaten Madiun
Authors: Winanto Bernardinus Yoga , Sayekti Rini Wahyu , Ismoyo M. Janu
Published: December 2022

Daerah Irigasi (DI) Kedungrejo Kabupaten Madiun memiliki luas baku sawah 1.538 ha. Daerah Irigasi Kedungrejo memiliki beberapa problematika yaitu Rencana Tata Tanam Global (RTTG) yang dibuat oleh Dinas Pengairan tidak terlaksana dengan baik di lapangan, debit sungai berlebih ketika musim hujan dan debit sungai minim ketika musim kemarau. Studi ini bertujuan untuk mengevaluasi kebutuhan air eksisting menggunakan metode Water Balance kemudian merencanakan pola tata tanam rencana untuk meningkatkan intensitas tanam ketika debit berlebih dan merencanakan jadwal rotasi pembagian air dengan menggunakan faktor K. Dari studi ini didapat hasil perhitungan debit andalan 80% maksimum sebesar 4.533,50 lt/dt dan minimum sebesar 0,00 lt/dt, lalu hasil evaluasi kebutuhan air eksisting dengan kondisi surplus air sebanyak 18 kali (50%) dan defisit air sebanyak 18 kali (50%) di mana intensitas tanam kondisi eksisting tahun 2014-2019 mencapai 284,32%. Untuk kebutuhan air dengan pola tata tanam rencana kondisi surplus air sebanyak 32 kali (89%) dan defisit air sebanyak 4 kali (11%) di mana intensitas tanam rencana dibuat sebesar 155,27%. Lalu rotasi pembagian air dengan faktor K terjadi sebanyak 4 kali.
Logotherapy is effective in increasing self-esteem, but caution is needed: A meta-analytic study
Authors: Diadiningrum Jihan Rahma , Yudiarso Ananta
Published: December 2022

Individuals with positive self-esteem recognize their personal qualities. They feel comfortable, optimistic, and confident about themselves. Conversely, individuals with negative self-esteem tend to experience poor quality of life. This study examines the effectiveness of logotherapy in increasing self-esteem. We conducted a meta-analysis by collecting and reviewing 14 research articles on logotherapy and self-esteem. We analyzed the data from the selected articles based on the number of participants (N), the average value (M), and the standard deviation (SD). The meta-analysis showed that logotherapy is a recommended and effective intervention to increase self-esteem.  
Keywords: logotherapy, meta-analysis, self-esteem
Persepsi keterlibatan ayah dalam pengasuhan dan masalah eksternalisasi pada remaja
Authors: Nur Maslina  , Syakarofath Agustin , Karmiyati Diah , Widyasari Dian Caesaria
Published: December 2022

Remaja rentan mengalami krisis identitas. Krisis ini mendorong sebagian remaja untuk mengeksternalisasi masalah mereka dengan melakukan perilaku menyimpang. Salah satu faktor yang mendorong masalah eksternalisasi pada remaja adalah persepsi mereka tentang keterlibatan ayah mereka. Penelitian ini bertujuan untuk mengetahui peran persepsi remaja terhadap keterlibatan ayah dalam masalah eksternalisasi mereka. Partisipan dalam penelitian ini adalah 498 siswa SMP Muhammadiyah di beberapa kota di Jawa Timur yang kami pilih berdasarkan teknik simple random sampling. Persepsi remaja tentang keterlibatan ayah mereka berbanding terbalik dengan masalah eksternalisasi mereka. Remaja dengan persepsi yang lebih tinggi tentang keterlibatan ayah mereka cenderung memiliki masalah eksternalisasi yang lebih rendah.
Kata kunci: remaja, keterlibatan ayah, eksternalisasi masalah
Fishing Business Performance Analysis: An Entrepreneurial Approach
Authors: Rauf Rusdiaman , Wijaya Hengki
Published: December 2022

AbstractEntrepreneurship requires work motivation, entrepreneurial learning and entrepreneurship commitment to improving business performance in various types of businesses, especially in the business activities of fishing communities. This study used a purposeful sample of 70 respondents and focused on fishermen who use boats as fishing equipment in the sea.  The results of the study indicate that work motivation and commitment to entrepreneurship directly and partially have a significant positive effect on business performance, while entrepreneurial learning has an insignificant effect, while simultaneously work motivation, entrepreneurial learning and commitment to entrepreneurship have a positive and significant effect on business performance.  Keywords: Work motivation, entrepreneurial learning, entrepreneurial commitment,               business performance Analisis Kinerja Usaha Penangkapan Ikan:Suatu Pendekatan Kewirausahaan AbstrakKewirausahaan membutuhkan motivasi kerja, pembelajaran kewirausahaan dan komitmen kewirausahaan untuk meningkatkan kinerja usaha di berbagai jenis usaha, terutama dalam kegiatan usaha masyarakat nelayan. Metode penelitian ini dilakukan secara purposive pada nelayan yang memiliki perahu sebagai alat tangkap ikan di laut dengan jumlah sampel 70 responden. Hasil penelitian menunjukkan bahwa motivasi kerja dan komitmen berwirausaha secara langsung dan parsial berpengaruh positif signifikan terhadap kinerja usaha, sedangkan pembelajaran kewirausahaan berpengaruh tidak signifikan, sedangkan secara simultan motivasi kerja, pembelajaran kewirausahaan dan komitmen berwirausaha berpengaruh positif dan signifikan. pada kinerja usaha. Kata kunci: Motivasi kerja, pembelajaran wirausaha, komitmen wirausaha, kinerja usaha
PUBLIC PARTICIPATION IN REALIZING POLICY ACCOUNTABILITY COVID-19 PANDEMIC HANDLING AT YOGYAKARTA SPECIAL REGION
Authors: Ahdiyana Marita , Ulifah Nuri
Published: December 2022

This study aims to describe community participation in realizing policy accountability for handling the covid-19 pandemic in the Special Region of Yogyakarta. The research design used was a descriptive study with a qualitative approach. Community participation was analyzed using a spectrum of five levels of participation. The results showed that community participation has manifested itself at every level of the spectrum of public participation. However, community participation is still limited to passive participation, where the community is only involved in policy implementation. At the information level, various information systems have been created to provide information, but not all of them can be accessed by the public. At consult level, various opinions from the community and stakeholders have received a good response and used as a consideration Governor. At the level of involvement, community has positioned as both a subject and an active participant in volunteering since the start of the pandemic. At the level of collaborate, collaboration has reached the stage of opening space for participation from various stakeholders.  Last at the empower level, it has been carried out through various efforts. starting from the RT, RW, and Village levels. However, there has been no coordinated effort and clear division of roles in implementing the collaboration and empowerment.
МОРФОЛОГІЧНІ ТА ІМУНОГІСТОХІМІЧНІ ЗМІНИ В НАДНИРКОВИХ ЗАЛОЗАХ ХВОРИХ З ДОБРОЯКІСНИМИ НОВОУТВОРЕННЯМИ В ЗАЛЕЖНОСТІ ВІД ІНДЕКСУ МАСИ ТІЛА
Authors: Караченцев Юрій , Дубовик Віктор , Микитюк Мирослава , Яковцова Ірина , Товажнянська Віра
Published: December 2022

Мета дослідження. Провести морфологічний аналіз та аналіз рівня експресії рецепторів інсуліноподібних факторів росту 1 і 2 (рІФР-1 та рІФР-2, відповідно) у зразках видаленої під час хірургічного втручання тканини надниркових залоз (НЗ) у хворих на доброякісні новоутворення НЗ в залежності від індексу маси тіла (ІМТ).
Матеріали та методи. Проведено аналіз видалених під час хірургічного втручання НЗ. Нозологіями, що вивчалися, були вогнищева вузлова гіперплазія НЗ (ВГНЗ) та доброякісні новоутворення НЗ. Матеріал 37 спостережень був поділений на три групи: група 1 (група порівняння) (n=9) – пацієнти з ІМТ<25 кг/м2, група 2 (n=15) – пацієнти з ІМТ 25-30 кг/м2 і група 3 (n=13) – пацієнти з ІМТ >30 кг/м2. Мікропрепарати використовували для загальної оцінки стану тканин, мікроскопічного вивчення та проведення морфометричного дослідження НЗ. Проводили аналіз експресії рІФР-1 та рІФР-2 в тканині НЗ з використанням первинних моноклональних антитіл фірми DAKO (Данія), TermoScientific (Німеччина) та Diagnostic BioSystems (США).
Результати та їх обговорення. При імуногістохімічному дослідженні (ІГХ) тканини НЗ пацієнтів із надмірною масою тіла і ожирінням виявлено ​​помірну (2++) і виразну (3+++) експресію рІФР-1 при слабкій експресії в групі з нормальною масою тіла. Встановлено наявність сильного кореляційного зв’язку між виразністю експресії рІФР-1 та ІМТ в групах хворих з надлишковою масою тіла і ожирінням. Виразність експресії рІФР-1 має чітке односпрямоване зростання, що демонструє лінія тренду. У пацієнтів з нормальною масою тіла експресія рІФР-2 не спостерігалася. Встановлено, що зі зростанням ІМТ спостерігається тенденція до зниження експресії рІФР-2. Фокальну експресію рІФР-2 в НЗ було виявлено лише у пацієнтів з ожирінням.
Висновки: При ІГХ-дослідженні видалених зразків тканини НЗ пацієнтів з ВГНЗ і доброякісними новоутворення НЗ та надмірною масою тіла або ожирінням виявлено помірну і виразну відповідно експресію рІФР-1 при слабкій їх експресії в тканині надниркових залоз у пацієнтів з нормальною масою тіла. Встановлено наявність сильного кореляційного зв’язку між виразністю експресії рІФР-1 в зразках тканини НЗ та ІМТ, що може вказувати на участь ІФР-1 в патогенезі ВГНЗ та доброякісних новоутворень НЗ. Доросле населення України із надлишковою масою тіла та ожирінням може розглядатися як група ризику щодо розвитку ВГНЗ і доброякісних новоутворень надниркових залоз, що вимагає розробки відповідних скринінгових програм.
Prefiguring the Otokonoko Genre
Authors: Lewicki Riley Hannah
Published: December 2022

This article examines two manga, Stop!! Hibari-Kun! and No Bra, which prefigure the increasingly popular anime and manga genre of "Otokonoko" from a queer studies perspective. Otokonoko is a term which translate to “boy-girl”, “boy-daughter”, or “boy-princess” and is often translated into English as “cross-dresser”. The genre emerged in the early 2000s and has since become a popular point of reference and conversation both within and outside of anime and manga communities. Both the genre, and its titular characters have become iconic within both Japanese and Western online culture. As with most genres, the otokonoko genre is trope heavy, so it was decided to look at works that prefigure the genre to better understand the appeal without the weight of the traditions of the genre weighing too heavily on the content. Both Stop!! Hibari-Kun! and No Bra follow the story of a boy who becomes increasingly attracted to a gender ambiguous character assigned male at birth, but who appears female to most. Both manga are centrally about this conflict between the love interests’ perceived maleness and the protagonists perceived heterosexuality. The article analyses the appeal of each work to both male and trans feminine readers, because what would later become the otokonoko genre is written and read by both male and trans feminine readers. It also argues that these manga offer something unique from Western depictions of transgender lives, based on the popularity of manga and anime among Western trans feminine readers.
Carbon Taxation as An Instrument to Promote Wildfire Prevention and Avoid Biodiversity Loss in Portugal: An Order of Magnitude Analysis
Authors: Martins Pacheco Renata
Published: December 2022

Climate change is one of the main challenges of the current century. Emissions taxes are one of the proposed ways to help in addressing this issue. In this sense, Portugal has introduced an Addition Tax on Carbon Emissions through Law N. 82-D/2014. One of the most notorious impacts of climate change in the country is the wildfires increasing in frequency and intensity. Forests provide various ecosystem services not valued by traditional markets, such as carbon sequestration. Recently, Portugal has created new environmental policies that deal with fire prevention and biodiversity conservation through payment for ecosystem services schemes. In this context, the objective of this work was to perform an order of magnitude analysis of the revenue from the Addition Tax on Carbon Emissions (Law N. 82-D/2014) and contrast it with the investment costs of RCM N. 121/2019 (Payment for Ecosystem Services) and of RCM N. 59/2017 (Prescribed Burning Program). The results indicated that the Addition Tax revenue was much greater than the costs of the other two policies combined, even if expanding the use of prescribed burning in the country. This suggested that these policies can work synergistically, as development agendas recommend, such as the Sustainable Development Goals. This analysis framework might be helpful for other countries, especially in the Mediterranean Basin.
MiR-144 as a novel biomarker in breast cancer diagnosis and treatment
Authors: Tashatot Simin Pegah , Jafari Marandi Sayeh , Behjati Ardakani Reza
Published: December 2022

Exosomes naturally carry the biomolecules in the body; they perform this task efficiently without compromising the immune system and by breaking through all the biological barriers, so they can be the best choice for designing and introducing a drug and gene transfer system. Extraction of the exosomes from the cell culture medium was performed by precipitation with an Exoquick kit solution. Nanoparticle specificity analysis was performed using scanning electron microscopy and dynamic light scattering. Trizol reagent (Invitrogen) was used for RNA extraction. Single-strand cDNA synthesis was performed from the miRNA and RT-PCR. Data were analyzed using a threshold cycle comparative method and cell cycle analysis using flow cytometry. Exosomes containing miR-144 can dramatically decrease the expression level of crucial TGF-β pathway genes, SMAD4 and TGF-βR2, in breast cancer cells. Botulinum toxin A inhibits cancer cell growth by inhibiting the TGF-β pathway. The simultaneous combination of engineered exosomes containing miR-144 and bacterial botulinum toxin A has increased effects on inhibiting the TGF-β signaling pathway. It causes cell cycle arrest in breast cancer cells. The present study's findings showed that overexpression of miR-144 in breast tumor cells results in the packaging of miRNA in exosomes derived from these cells. As a result, the exosomal platform for nucleic acid transfer to the cell appears to be an effective transducer for gene transfer to the cell. It could be used as a suitable adjunct to cancer therapeutic studies.

Keywords: Breast cancer, botulinum toxin A, exosome, miRNA, biomarker.
The association of serum visfatin in women with polycystic ovary syndrome: A case-control study
Authors: Shamkhi Al- Ghazali Basima , Ali Mohammed Ayyam , Muhi Fahad Ahmed
Published: December 2022

Polycystic ovarian syndrome (PCOS) is the most common endocrinopathy among women of reproductive age. Visfatin is an adipokine secreted by fat tissue and macrophages involved in regulating glucose homeostasis, adipose tissue inflammation, chronic systemic inflammation, cardiovascular disease and endothelial dysfunction. The study sample (100 patients) includes 50 PCOS women and 50 control matched for age and body mass index (BMI). The women with PCOS were divided into obese or overweighed according to BMI ≥ 25 Kg/m2 and non-obese BMI ≤ 25 Kg/m2. The control group was also divided into obese and non-obese. The results showed that serum visfatin was significantly increased in obese women with POCS compared to obese control (5.61 ± 1.27 ng/mL vs. 0.48 ±0.28 ng/mL) and in non-obese women with polycystic ovarian syndrome compared to non-obese control (5.22± 1.36 ng/mL vs. 0.33± 0.26 ng/mL). These findings might suggest that visfatin could play a role in pathogenesis and the long-term consequences of PCOS.

Keywords: visfatin; polycystic ovarian syndrome; body mass index; obese women
Sample Bias in Web-Based Patient-Generated Health Data of Dutch Patients With Gastrointestinal Stromal Tumor: Survey Study
Authors: Dirkson Anne , den Hollander Dide , Verberne Suzan , Desar Ingrid , Husson Olga , van der Graaf Winette T A , Oosten Astrid , Reyners Anna K L , Steeghs Neeltje , van Loon Wouter , van Oortmerssen Gerard , Gelderblom Hans , Kraaij Wessel
Published: December 2022

Background

Increasingly, social media is being recognized as a potential resource for patient-generated health data, for example, for pharmacovigilance. Although the representativeness of the web-based patient population is often noted as a concern, studies in this field are limited.

Objective

This study aimed to investigate the sample bias of patient-centered social media in Dutch patients with gastrointestinal stromal tumor (GIST).

Methods

A population-based survey was conducted in the Netherlands among 328 patients with GIST diagnosed 2-13 years ago to investigate their digital communication use with fellow patients. A logistic regression analysis was used to analyze clinical and demographic differences between forum users and nonusers.

Results

Overall, 17.9% (59/328) of survey respondents reported having contact with fellow patients via social media. Moreover, 78% (46/59) of forum users made use of GIST patient forums. We found no statistically significant differences for age, sex, socioeconomic status, and time since diagnosis between forum users (n=46) and nonusers (n=273). Patient forum users did differ significantly in (self-reported) treatment phase from nonusers (P=.001). Of the 46 forum users, only 2 (4%) were cured and not being monitored; 3 (7%) were on adjuvant, curative treatment; 19 (41%) were being monitored after adjuvant treatment; and 22 (48%) were on palliative treatment. In contrast, of the 273 patients who did not use disease-specific forums to communicate with fellow patients, 56 (20.5%) were cured and not being monitored, 31 (11.3%) were on curative treatment, 139 (50.9%) were being monitored after treatment, and 42 (15.3%) were on palliative treatment. The odds of being on a patient forum were 2.8 times as high for a patient who is being monitored compared with a patient that is considered cured. The odds of being on a patient forum were 1.9 times as high for patients who were on curative (adjuvant) treatment and 10 times as high for patients who were in the palliative phase compared with patients who were considered cured. Forum users also reported a lower level of social functioning (84.8 out of 100) than nonusers (93.8 out of 100; P=.008).

Conclusions

Forum users showed no particular bias on the most important demographic variables of age, sex, socioeconomic status, and time since diagnosis. This may reflect the narrowing digital divide. Overrepresentation and underrepresentation of patients with GIST in different treatment phases on social media should be taken into account when sourcing patient forums for patient-generated health data. A further investigation of the sample bias in other web-based patient populations is warranted.
Effect of Feeding Kiwifruit (Actinidia deliciosa) Extract on Survival Rate and Reproductive Organ Morphology of Fruit Fly (Drosophila melanogaster Meigen, 1830) Ultraviolet Light Irradiation
Authors: Nafisa Kusumawati  , Ignatius Sudaryadi
Published: December 2022

UV (ultraviolet) radiation is one of the radiations that are naturally emitted by the sun. As the result of climate changes, the earth's ozone layer changes and the UV light radiation to the earth's surface increases. The negative effect of  UV  radiation is increase due to the production of ROS (Reactive Oxygen Species) or free radicals in the body. UV radiation protection can be done by increasing the intake of antioxidant-rich foods as free radical inhibitors. Actinidia deliciosa or kiwifruit is a antioxidants-rich fruit including vitamin C.    This research was carried out with Drosophila melanogaster as a animal model because it is easy to breed in the laboratory, has a short life cycle, and produces large numbers of eggs. Drosophila melanogaster or fruit flies are the most commonly used of animal models in the biomedical and pharmacological fields. This study aims to determine the effect of UV radiation on fruit fly survival at the larval, pupa, and imago stages and the morphology changes of male and female reproductive organs, as well as to determine the effect of feeding kiwi fruit extract on survival rate and morphology changes of male and female reproductive organs of UV irradiated fruit fly. This research was conducted by providing UV exposure treatment and without UV radiation treatment to fruit flies for 2 hours on banana and kiwi feed medium. Data analysis was carried out with the One Way Anova test followed by the Duncan test. The results showed that UV radiation could affect the survival and morphology of the reproductive organs of fruit flies. The survival rate in the control treatment was 58%, PK treatment 81%, PPUV treatment 45%, and PKUV treatment 47%.
Effects of Customer Satisfaction on Water Utility Business Performance: A Case Study of Mbinga Urban Water Supply and Sanitation Authority
Authors: Leticia Tweve
Published: December 2022

Customer satisfaction is critical in determining why businesses succeed or fail, as well as why they perform at different levels. Yet, the performance of at Mbinga Urban Water Supply and Sanitation Authority (MBIUWASA) for such a long time became very poor due to different problems such as dissatisfaction of customers making them delay paying their bills on time in lieu of unreliable services. This study analysed the effects of customer satisfaction on water utility business performance at Mbinga Urban Water Supply and Sanitation Authority (MBIUWASA). Specifically, the study aimed at examining the influence of customer satisfaction on return on asset (RoA), the relationship between customer satisfaction and return on equity (RoE) and the impact of customer satisfaction on return of investment (RoI). Case study research design was used along with mixed approach. A sample size of 50 customers and MBIUWASA staff was utilized. Simple random sampling was used to select respondents as to get views from them. Tools used included questionnaire, in-depth interview and documentary review. Quantitative and qualitative data were analysed descriptively along with the use of content analysis. Moreover, regression analysis was used to capture the relationship between variables. The study revealed that MBIUWASA customers are not satisfied with the service provided leading to poor performance. The regression analysis indicates that the coefficient of correlation R was 0.840 an indication of positive relationship between variables. Coefficient of adjusted determination R2 was 0.706 which changes to 70.6% an indication of changes of dependent variable (RoA, RoE and RoI) that can be explained by customer satisfaction. The residual of 29.4% can be explained by other variables beyond the scope of the current study. The study concluded that MBIUWASA needs to find out ways of investing much on water sources to be able to supply water to the large number of customers while adhering to quality service provision.
Application des expériences professionnelles françaises en Yougoslavie des débuts du socialisme 1945 / 46 – 1952 : quelques exemples
Authors: Ilic Sasa
Published: December 2022

Bien que dans des circonstances exiguës dues aux différences politiques et idéologiques, à l’éloignement géographique et à la pénurie mutuelle de main-d’œuvre, la participation de l’expérience française et les Françaises à la vie économique et non économique de la Yougoslavie au début du socialisme n’a pas été exclue. L’analyse des sources d’archives et de la littérature dans le document montre les formes de cette coopération et surtout la participation de certains experts français à des activités dans lesquelles la Yougoslavie souffrait d’une grave pénurie de personnel. Les offres des institutions professionnelles et scientifiques françaises pour un plus grand nombre de formes de coopération n’ont pas toujours été acceptées. Cependant, l’initiative individuelle ou collective d’experts français, pour la plupart économiques, a porté ses fruits, surtout après la rupture avec l’URSS. Bien que peu nombreux, certains des experts français engagés ont laissé une empreinte significative par leur travail, notamment dans le domaine de l’hydraulique, mais aussi dans le sport.
Sobre Juan Pablo Vivaldo Martínez, La vejez en el porfiriato (1876-1910). Representaciones en prensa y literatura mexicana
Authors: Otero Hernán
Published: December 2022

Reseña sobre Juan Pablo Vivaldo Martínez, La vejez en el Porfiriato (1876-1910). Representaciones en prensa y literatura mexicana, libro electrónico (México: Universidad Nacional Autónoma de México, 2020).
Sobre Familias e infancias en la historia contemporánea: jerarquías de clase, género y edad en Argentina
Authors: Sosenski Susana
Published: December 2022

Reseña sobre Familias e infancias en la historia contemporánea: jerarquías de clase, género y edad en Argentina, comp. de Isabella Cosse (Córdoba, Argentina: Editorial Universitaria Villa María, 2021).
Sobre Diccionario de protagonistas del mundo católico en México. Siglo XX
Authors: Traslosheros Jorge E.
Published: December 2022

Reseña sobre Diccionario de protagonistas del mundo católico en México. Siglo XX, coord. de Gabriela Aguirre, Camille Foulard, Austreberto Martínez, Andrea Mutolo, Nora Pérez Rayón, Franco Savarino, Yves Solís y Valentina Torres Septién (México: Universidad Autónoma Metropolitana-Unidad Azcapotzalco, Unidad Xochimilco, 2021).
Quantum Computing
Authors: Narang Mrinal , Marwaha Jayant , Kaur Gurpreet , Bhatia Dr. Manjot Kaur , Sandilya Ritesh
Published: December 2022

Abstract: Quantum computing is a modern calculation method that is based on the science of quantum mechanics. These phenomena include the bizarre behavior of particles at the atomic and subatomic levels, and the way that these particles can be in multiple states simultaneously. The field of computer science is a great mix of physics, math, and information theory. This technology provides high computing power, low power consumption, and exponential speed by controlling the behavior of small physical objects, such as atoms. Atoms, electrons, photons, etc. are all elements of the physical world. We would like to introduce the basics of quantum computing, and some of the ideas behind it. This article begins with the origins of the classical computer and discusses all the improvements and transformations that have been made due to its limitations thus far, then moves on to the basic operations of quantum computing and results in quantum properties such as superposition, entanglement, and interference.
Restaurant Review Analysis using Natural Language Processing
Authors: Kunekar Pankaj , Arya Haripriya , Dighekar Abhishek , Bagade Atharv , Garud Harish , Abdelbari Eissa
Published: December 2022

Abstract: The most effective tool any restaurant can have is the capability to track the daily sales of their food and beverage. Currently, recommendation systems plays an important role in both academia and industry. These are very helpful to manage an overload of information. In this paper, applied machine learning techniques for user reviews were used and valuable information in the reviews were analyzed. For both the customers and the owners, reviews are useful to make data-driven decisions. We built a machine learning model with Natural Language Processing techniques which captures a user’s opinions from user’s reviews. A lot of businesses fail due to the lack of profit and a lack of proper improvement measures. Mostly, restaurant owners face a lot of difficulties to enhance their productivity.
5G: Overview, Challenges and Benefits
Authors: Arjun Jadhav Akshay , Kishor Mali Kiran , Jadhav Prof. Snehal
Published: December 2022

Abstract: 5G Is a advances technology in world around us but also dynamic the wireless industry to develop the next generation of network technology. December 1, 2018, South Korea became the first country to offer 5G.5G is a high frequency band and different device support are 5G.5G main advantages is high speed and effective and efficiency technology.5G is wireless backhaul connection or high bandwidth optical fibber.
Exchange Rate Fluctuation on Emerging Market and Developing Countries in Europe
Authors: Khairunnisa Nabilah , Zuhroh Idah
Published: December 2022

This study investigates the determinants of the exchange rate in European Emerging Market and Developing Countries (EMDEs), including Albania, Bulgaria, Hungary, Rep. Moldova, Rep. North Macedonia, Romania, Russia, and Ukraine. This study uses secondary data from 2000-2019 in time series and panel data with a sample of 8 countries sourced from the United Nations Conference on Trade and Development, the International Monetary Fund, and the World Bank. A regression method was used for time series data to analyze each country, and panel data was used for eight countries. Time series regression results show the influence of different relationships in each country. Meanwhile, the panel data regression found that exchange rate fluctuations in EMDE's European countries, GDP growth, and Terms of Trade (ToT) had a significant positive effect on exchange rates. It means that an increase in GDP and ToT growth affects the exchange rate appreciation, and a decrease in GDP and ToT growth affects the exchange rate depreciation in EMDE's European countries. Meanwhile, inflation and loan interest rates have a significant adverse effect on the exchange rate. It means that every decrease in inflation and interest rates on loans affects the appreciation of the exchange rate and vice versa, increases in inflation and interest rates on loans result in exchange rate depreciation in EMDE's European countries.
Nueva evidencia en el tratamiento de la enfermedad renal diabética: ¿qué aporta la finerenona?
Authors: Fontalvo Jorge Rico , Daza Arnedo Rodrigo , Aguilar Salcedo Nataly , Alfaro Mercedes , Navas Torrejano Diana , Cardona Blanco María , Uparella Gulfo Isabela , Raad Sarabia Maria , Abuabara Franco Emilio , Cabrales Jose
Published: December 2022

Contexto: la enfermedad renal diabética (ERD) es la primera causa a nivel mundial de enfermedad renal crónica (ERC) e impacta directamente en el riesgo cardiovascular y mortalidad de los pacientes con diabetes mellitus (DM). La finerenona, un antagonista selectivo del receptor mineralocorticoide (ARM), ha sido descrito en diversos estudios recientes como un fármaco que contribuye a la reducción de la progresión de la ERD y la disminución del riesgo cardiovascular, con un adecuado perfil de seguridad.
Objetivo: realizar una revisión de la literatura sobre el impacto de la finerenona en la progresión del daño renal y el riesgo cardiovascular en los pacientes con ERD.
Metodología: se realizó una búsqueda sistemática en diversas fuentes: PubMed (Medline, Biblioteca del Congreso de los Estados Unidos), Science Direct, Scopus, Embase y Lilacs; la búsqueda fue restringida a referencias en idioma español e inglés, sin límites en la fecha de publicación. Se utilizaron las siguientes palabras clave en el idioma inglés: diabetic renal disease, chronic kidney disease, diabetes mellitus, spironolactone, eplerenone, finerenone, mineralocorticoid receptor antagonist y sus correspondientes versiones en español.
Resultados: Las referencias encontradas en la búsqueda fueron revisadas entre los diferentes autores para, posteriormente, proceder a realizar la elaboración del documento.
Conclusiones: la finerenona es un medicamento que brinda cardio y nefroprotección en pacientes con ERD de fenotipo albuminúrico.
Effervescent Tablets: Everything You Need To Know
Authors: Lodhi Vineeta Devi , Jadon Arvind Singh , Sen Jyoti , Jain Prateek Kumar , Thakur Bhupendra Singh , Khare Basant , Jain Anushree
Published: December 2022

Oral dosage forms are the most popular way of taking medication, despite having some disadvantages compared with other methods like risk of slow absorption of the medicament, which can be overcome by administering the drug in liquid form, therefore, possibly allowing the use of a lower dosage. However, instability of many drugs in liquid dosage form limits its use. Effervescent technique can be used as alternate to develop a dosage form which can accelerate drug disintegration and dissolution, is usually applied in quick release preparations. Along with the development of new pharmaceutical technique, effervescent tablets are more and more extensively to adjust the behavior of drug release, such as in sustained and controlled release preparations, pulsatile drug delivery systems, and so on. In this review we have discussed about formulation, evaluation, advantages of effervescent tablets and also demonstrated the new applying of effervescent technique in effervescent tablets.
Keywords: Effervescent tablets. Carbon tablet, Effervescent granules.
The Effectiveness of Curcumin on Dysmenorrhea
Authors: Shrivastav Shubhangi , Tyagi Ravindra , Singh Meenakshi , Jha Sudhanshu
Published: December 2022

Menstruation is a cycle of oocyte release and preparing uterus for possible pregnancy if fertilization occurs. It begins at puberty and ends at menopause with an average duration of 28 days. Primary menstrual pain is a problem for women throughout the world that can affect daily life. Painful menstruation, also known as dysmenorrhea, is one of the most common women’s problems. Most women begin having dysmenorrhea during adolescence, usually within four to five years of the first menstrual period. Painful periods become less common as women age. For the treatment of dysmenorrheal much herbal medicine are use. Curcumin is one of the best phytochemical which is isolated from Curcuma longa L., is a fat-soluble natural compound which accumulative evidences have demonstrated that it can use to treat dymenorrhea. The objective of this paper is to analyze through literature regarding primary dysmenorrhea and natural herbal used to relieve the pain. Data from previous research show that curcumin and is the best candidates for relieving primary menstrual pain.
Keywords: Menstrual cycle, Dysmenorrhea, Curcumin, Curcuma longa
A autômata: a unheimlich no tema do duplo
Authors: Drummond Ana Luiza Duarte de Brito
Published: December 2022

Partindo do mito de Medusa às discussões propostas por Sigmund Freud em “Das unheimliche”, este trabalho procura destacar a unheimlich na angústia ligada à figura da autômata. Assim, ele desperta a atenção para um tema pouco trabalhado ou mesmo ignorado pela crítica literária, especialmente aquela que se debruça sobre o tema do duplo no romance moderno, ao exibir a complexa rede de desejos e frustrações que ligará o duplo à autômata, em diversas obras modernas, num núcleo único, mortal e inquietantemente infamiliar.
As Estórias dentro da História: mapeando a nação no Museu da Revolução de João Paulo Borges Coelho
Authors: Sousa Sandra , Khan Sheila
Published: December 2022

Museu da Revolução, o mais recente romance do escritor moçambicano João Paulo Borges Coelho, oferece ao leitor uma indagação sagaz e minuciosa sobre como lidar de uma forma ponderada e reparadora com o passado moçambicano na sua relação com os legados da colonialidade na pós-colonialidade. Acompanhando o escritor neste exercício complexo e plural do reconhecimento de outras estórias, narrativas e memórias construídas como menores dentro de uma História maior, o presente artigo pretende articular com a mundanidade pós-colonial o emergente vigor dos estudos da pós-memória. Com precisão, na sua capacidade de interagir com a ancestralidade colonial e decolonial sob uma perspetiva da reparação histórica, do dever de memória e da cidadania estética e cívica atenta à compreensão e desconstrução de velhas lógicas sobreviventes da colonialidade no presente pós-colonial humano global.
Entre ficção e crítica: Abdellah Taïa leitor do orientalismo de André Gide
Authors: Vilarino Júnior
Published: December 2022

Propõe-se, neste artigo, uma leitura do complexo entrelaçamento de ficção, história, crítica literária, filosofia política e interseccionalidade, urdido na metaficção Aquele que é digno de ser amado (2017), de Abdellah Taïa, como forma de apropriação da obra de André Gide. Debate-se a releitura culturalista, efetuada pelo romance, do orientalismo sexual efebófilo do autor francês. Discute-se a analogia política estabelecida entre suas práticas sexuais com rapazes africanos e uma trama narrativa na qual o cotidiano da relação amorosa entre dois intelectuais, um marroquino imigrante em Paris e um nativo parisiense, está imbuído de motivações orientalistas, as quais Ahmed, narrador-personagem, chamará de neocolonialistas. Espera-se demonstrar o pensamento crítico de Taïa ao expor a complacência da crítica literária em língua francesa relativa à objetificação dos corpos e das vidas dos sujeitos árabes representados na obra gideana. Para tanto, trata-se da recepção dos estudos culturais na França, de acordo com BRISSON (2018) e SMOUTS (2010). Apresentam-se sumariamente os pressupostos metodológicos de SAID (1990; 1995) sobre o orientalismo, bem como uma contextualização, na obra de Gide, de seu “turismo oriental-sexual”. Passa-se, então, à análise da “transcontextualização” (HUTCHEON, 1985) irônica empreendida pela narrativa de Abdellah Taïa. Recorre-se, igualmente, ao conceito de não-lugar da literatura de SOUZA (1999), para compreender os juízos de valor acerca do texto literário na crítica cultural e nos estudos literários. Da fortuna crítica de Abdellah Taïa e André Gide, invocam-se HEYNDELS (2020); SANSON (2013) e KOPP (2019), respectivamente.