bluuebunny/crossref_metadata_2025 huggingface dataset:
A Prediction Methodology of Energy Consumption Based on Deep Extreme Learning Machine and Comparative Analysis in Residential Buildings
Authors: Fayaz Muhammad , Kim DoHyeun
Published: September 2018

In this paper, we have proposed a methodology for energy consumption prediction in residential buildings. The proposed method consists of four different layers, namely data acquisition, preprocessing, prediction, and performance evaluation. For experimental analysis, we have collected real data from four multi-storied residential building. The collected data are provided as input for the acquisition layer. In the pre-processing layer, several data cleaning and preprocessing schemes were deployed to remove abnormalities from the data. In the prediction layer, we have used the deep extreme learning machine (DELM) for energy consumption prediction. Further, we have also used the adaptive neuro-fuzzy inference system (ANFIS) and artificial neural network (ANN) in the prediction layer. In the DELM different numbers of hidden layers, different hidden neurons, and various types of activation functions have been used to achieve the optimal structure of DELM for energy consumption prediction. Similarly, in the ANN, we have employed a different combination of hidden neurons with different types of activation functions to get the optimal structure of ANN. To obtain the optimal structure of ANFIS, we have employed a different number and type of membership functions. In the performance evaluation layer for the comparative analysis of three prediction algorithms, we have used the mean absolute error (MAE), root mean square error (RMSE) and mean absolute percentage error (MAPE). The results indicate that the performance of DELM is far better than ANN and ANFIS for one-week and one-month hourly energy prediction on the given data.
A Novel Model Incorporating Geomechanics for a Horizontal Well in a Naturally Fractured Reservoir
Authors: Wang Mingxian , Xing Guoqiang , Fan Zifei , Zhao Wenqi , Zhao Lun , Song Heng
Published: September 2018

Fracture aperture of a fractured reservoir can be affected by both matrix elasticity and fracture compressibility when the reservoir pressure decreases, namely stress sensitivity. An elasticity parameter coupling Young’s modulus and Poisson’s ratio was introduced to reflect this geomechanical behavior, and a new model incorporating geomechanics was developed to analyze the flow behavior of a horizontal well in a naturally fractured reservoir. Pressure solutions for two cases—uniform-flux and infinite-conductivity—were derived, respectively. For the uniform-flux case, the effect of dimensionless elasticity parameter on the pressure-drop profile becomes stronger with continuing production, and the profile may be like a bow. Nine flow regimes can be observed on the transient response of the infinite-conductivity case. Stress sensitivity mainly affects the late-flow period and a larger dimensionless elasticity parameter causes a greater pressure drop. Due to stress sensitivity, the pressure derivative curve exhibits an upward tendency in the pseudo-radial flow regime, and the slope is greater than “1” in the pseudo-steady flow regime. For KT-I formation in the North Truva field, its elasticity parameter decreases with the increase of Young’s modulus or Poisson’s ratio and ranges from 8 × 10−8 Pa−1 to 1.1 × 10−7 Pa−1. Meanwhile, the transient response of H519 has a slight negative correlation with Young’s modulus and Poisson’s ratio in the pseudo-steady flow regime.
Relationship between Soil Organic Carbon Stocks and Clay Content under Different Climatic Conditions in Central China
Authors: Zhong Zekun , Chen Zhengxing , Xu Yadong , Ren Chengjie , Yang Gaihe , Han Xinhui , Ren Guangxin , Feng Yongzhong
Published: September 2018

Understanding the association between soil organic carbon (SOC) and texture under different climatic conditions is important for assessing the effects of future climate changes on SOC stocks. In this study, we conducted a climatic gradient experiment covering three climate types (humid, sub-humid, and semi-arid) with a steep rainfall ranging from 345 to 910 mm, and specifically determined SOC dynamics, clay content, and vegetation and soil characteristics. The results showed that, from semi-arid to humid regions, SOC stocks, SOC, and clay content increased synchronously and were closely related in layers of depths of both 0–10 and 10–20 cm. In contrast, under similar climatic conditions, SOC dynamics were mainly affected by vegetation and soil characteristics, especially total nitrogen and total phosphorus dynamics, but not the soil clay content. Therefore, these results suggest that the relationship between SOC stocks and clay content depended on scale sizes. Specifically, on a larger scale with different climatic gradients, the climate may partly determine the changes in SOC and clay dynamics, whereas, at a smaller scale where climate type does not vary considerably, the changes in SOC stocks and clay content may be related to vegetation diversity and soil nutrient dynamics. These results may contribute to future model development and the projection of changes in soil carbon storage.
Stakeholder Participation in Natura 2000 Management Program: Case Study of Slovenia
Authors: Laktić Tomislav , Pezdevšek Malovrh Špela
Published: September 2018

The Natura 2000 network, which is one of the largest networks of protected areas in the world, is the core pillar in the European Union’s biodiversity conservation policy. To achieve the national enforcement of Natura 2000 and to overcome implementation problems, effective policy measures are needed, and participation among different stakeholders is required. The aim of this paper was to evaluate the process of formulation of the Natura 2000 Management Program (2015–2020) in Slovenia based on a set of criteria and indicators for the evaluation of a participatory process, and to present the differences between the stakeholders’ evaluations according to their role in the implementation process. For that purpose, stakeholders were divided into two groups—stakeholders from project partner’s institution, and others. The research was done in two steps: First, in-depth semi-structured interviews with 17 representatives of the key stakeholders’ institutions or organizations that were involved in the formulation of the Natura 2000 Management Program were carried out; in the second, a survey with 266 stakeholders involved in the formulation and decision-making process was conducted. Overall, the results show that the participatory process was well organized, independent and fair; however, not all of the requisite conditions for successful participation were fulfilled, as was shown with the sub-criteria of transparency. The only difference between the groups exists in the evaluations of the sub-criteria transparency of the process. The group of stakeholders from the project’s partner institutions were more satisfied with the transparency of the process, as the average value was 3.36, compared to the others where the average value of satisfaction was 2.80. This indicates the need for an improved, novel, and innovative approach that leads to multi-level governance.
Simulated Impacts of Soy and Infrastructure Expansion in the Brazilian Amazon: A Maximum Entropy Approach
Authors: Frey Gabriel P. , West Thales A. P. , Hickler Thomas , Rausch Lisa , Gibbs Holly K. , Börner Jan
Published: September 2018

Historically, the expansion of soy plantations has been a major driver of land-use/cover change (LUCC) in Brazil. While a series of recent public actions and supply-chain commitments reportedly curbed the replacement of forests by soy, the expansion of the agricultural commodity still poses a considerable threat to the Amazonian and Cerrado biomes. Identification of areas under high risk of soy expansion is thus paramount to assist conservation efforts in the region. We mapped the areas suitable for undergoing transition to soy plantations in the Legal Amazon with a machine-learning approach adopted from the ecological modeling literature. Simulated soy expansion for the year 2014 exhibited favorable validation scores compared to other LUCC models. We then used our model to simulate how potential future infrastructure improvements would affect the 2014 probabilities of soy occurrence in the region. In addition to the 2.3 Mha of planted soy in the Legal Amazon in 2014, our model identified another 14.7 Mha with high probability of soy conversion in the region given the infrastructure conditions at that time. Out of those, pastures and forests represented 9.8 and 0.4 Mha, respectively. Under the new infrastructure scenarios simulated, the Legal Amazonian area under high risk of soy conversion increased by up to 2.1 Mha (14.6%). These changes led to up to 11.4 and 51.4% increases in the high-risk of conversion areas of pastures and forests, respectively. If conversion occurs in the identified high-risk areas, at least 4.8 Pg of CO2 could be released into the atmosphere, a value that represents 10 times the total CO2 emissions of Brazil in 2014. Our results highlight the importance of targeting conservation policies and enforcement actions, including the Soy Moratorium, to mitigate future forest cover loss associated with infrastructure improvements in the region.
Stem Radius Variation in Response to Hydro-Thermal Factors in Larch
Authors: Tian Yuan , Zhang Qiuliang , Liu Xuan , Meng Meng
Published: September 2018

The response mechanism of the tree stem radius variation to hydro-thermal factors is complex and diverse. The changes of TWD (tree water deficit-induced stem shrinkage) and GRO (growth-induced irreversible stem expansion) are respectively driven by different factors, so that their responses to hydro-thermal factors are different. The stem radius variation and its matching hydro-thermal factors experimental data was measured and determined at 0.5 h time scale in larch (Larix gmelini Rupr.) forest of the Daxing’anling region of the most northeastern part of China. Response characteristics of the stem radius variation to hydro-thermal factors have been found by analyzing the data under different time windows. The stem radius variation mainly responded to the changes in precipitation and relative humidity. The main driving factors for TWD were sap flow density and solar radiation. The response of GRO to hydro-thermal factors was complex, varied a lot under different time scales. During the analysis of the response of tree radial growth, changes of the stem radius can be divided to TWD and GRO to implement separate studies on their responses to hydro-thermal factors. In this way, it becomes easier to discover the response of TWD under drought stress and the responding mechanism of GRO to hydro-thermal factors.
Discovering the Health Promoting Potential of Fermented Papaya Preparation—Its Future Perspectives for the Dietary Management of Oxidative Stress During Diabetes
Authors: Somanah Jhoti , Putteeraj Manish , Aruoma Okezie I. , Bahorun Theeshan
Published: September 2018

The simplistic morphological characteristics of Carica papaya fruit or “pawpaw” should not be the cause for underestimating its potential as a nutraceutical. The market for papaya has been expanding at a staggering rate, partly due to its applicability as a biofortified product, but also due to its phytochemical properties and traditional health benefits. Papaya or formulations of fermented papaya promotion (FPP) display effective free radical scavenging abilities thought to be influenced by its phenolic, carotenoid, flavonoid, or amino acid profile. The antioxidant properties of FPP have been extensively reported in literature to potently target a broad spectrum of free radical-induced diseases ranging from neurological impairments, such as senile dementia, to systemic diseases, to its interference at the cellular level and the support of normal biological ageing processes. FPP has thus been extensively investigated for its ability to exert cellular protective effects and reduce oxidative stress via the mitigation of genetic damage, reduction of lipid peroxidation, and enzymatic inactivation in specific diseases. The focus of this review is to appraise the potential of oxidative stress reduction strategies of FPP and discuss its holistic approach in disease prevention and management, with a particular focus on diabetes and cancer. However, with the current lack of information surrounding its mechanism of action, this review wishes to set the stage and aspire researchers to more profoundly investigate molecular pathways related to how FPP can unequivocally contribute to wellness in an aging population.
Complexity on the Menu and in the Meal
Authors: Spence Charles
Published: September 2018

Complexity is generally perceived to be a desirable attribute as far as the design/delivery of food and beverage experiences is concerned. However, that said, there are many different kinds of complexity, or at least people use the term when talking about quite different things, and not all of them are relevant to the design of food and drink experiences nor are they all necessarily perceptible within the tasting experience (either in the moment or over time). Consequently, the consumer often needs to infer the complexity of a tasting experience that is unlikely to be perceptible (in its entirety) in the moment. This paper outlines a number of different routes by which the chef, mixologist, and/or blender can both design and signal the complexity in the tasting experience.
Physicochemical Properties of Hom Nil (Oryza sativa) Rice Flour as Gluten Free Ingredient in Bread
Authors: Thiranusornkij Lalana , Thamnarathip Parichart , Chandrachai Achara , Kuakpetoon Daris , Adisakwattana Sirichai
Published: September 2018

Hom Nil (Oryza sativa), a Thai black rice, contains polyphenolic compounds which have antioxidant properties. The objective of this study was to investigate physicochemical properties of Hom Nil rice flour (HN) and its application in gluten free bread by using Hom Mali 105 rice flour (HM) as the reference. The results demonstrated that HN flour had significantly higher average particle sizes (150 ± 0.58 µm), whereas the content of amylose (17.6 ± 0.2%) was lower than HM flour (particle sizes = 140 ± 0.58 µm; amylose content = 21.3 ± 0.6%). Furthermore, HN contained higher total phenolic compounds (TPC) (2.68 ± 0.2 mg GAE/g flour), total anthocyanins (293 ± 30 mg cyanidin-3-glucoside/g flour), and the ferric reducing antioxidant power (FRAP) (73.5 ± 1.5 mM FeSO4/g) than HM flour (TPC = 0.15 mg GAE/g flour and FRAP = 2.24 mM FeSO4/g flour). In thermal properties, the onset temperature (To), the peak temperature (Tp) and the conclusion (Tc) temperature of HN flour were similar to the values of HM flour. However, HN flour had lower enthalpy change (ΔH) than HM flour. The results showed that HN flour had lower swelling power and higher solubility than HM flour at the temperature between 55 °C and 95 °C. In pasting properties, HN flour also showed lower peak, trough and breakdown viscosity than HM flour. In addition, the bread samples prepared by HN flour had higher value of hardness and lower value of cohesiveness than the bread prepared from HM flour. Taken together, the findings suggest that HN flour could be used as an alternative gluten-free ingredient for bread product.
Reverse Shock Emission from Short GRBs
Authors: Lloyd-Ronning Nicole
Published: September 2018

We investigate the expected radio emission from the reverse shock of short GRBs, using the fitted afterglow parameters. In light of recent results suggesting that in some cases the radio afterglow is due to emission from the reverse shock, we examine the extent to which this component is detectable for short GRBs. In some GRBs, the standard synchrotron shock model predicts detectable radio emission from the reverse shock when none was seen. Many physical parameters play a role in these estimates, and our results highlight the need to explore the fundamental processes involved in GRB particle acceleration and emission more deeply. However, with a more rapid follow-up, we can test our standard model of GRBs, which predicts an early, radio bright reverse shock in many cases.
B Chromosome System in the Korean Field Mouse Apodemus peninsulae Thomas 1907 (Rodentia, Muridae)
Authors: Borisov Yuri M. , Zhigarev Igor A.
Published: September 2018

In this paper, we analyzed B chromosome variation in Korean field mouse Apodemus peninsulae Thomas 1907 (Rodentia, Muridae) based on a 40-year study of karyotypes collected from geographically distant populations in East Siberia, North Mongolia, China, the Russian Far East, and Japan (Hokkaido). We developed the database of individual variants of B chromosome systems in A. peninsulae. In Siberian populations all animals had Bs. The karyotypes of the studied animals contain from 1 to 30 Вs differing in size and morphology. Analysis of B chromosome systems in 598 individuals from different localities of the range shows the presence of 286 variants of Вs combinations in these animals. Unique sets of B morphotypes make up most of these variants (64.7 ± 1.3%), probably suggesting that individual Bs systems normally result from stochastic processes in the populations. The proportion of animals with a large number of Bs gradually decreases, probably due to increased complexities in the inheritance of large numbers of Bs. A. peninsulae is thus proposed as a good model for studying the origin and evolution of extra elements in the karyotype.
Lysine Acetylation Regulates Alanyl-tRNA Synthetase Activity in Escherichia coli
Authors: Umehara Takuya , Kosono Saori , Söll Dieter , Tamura Koji
Published: September 2018

Protein lysine acetylation is a widely conserved posttranslational modification in all three domains of life. Lysine acetylation frequently occurs in aminoacyl-tRNA synthetases (aaRSs) from many organisms. In this study, we determined the impact of the naturally occurring acetylation at lysine-73 (K73) in Escherichia coli class II alanyl-tRNA synthetase (AlaRS) on its alanylation activity. We prepared an AlaRS K73Ac variant in which Nε-acetyl-l-lysine was incorporated at position 73 using an expanded genetic code system in E. coli. The AlaRS K73Ac variant showed low activity compared to the AlaRS wild type (WT). Nicotinamide treatment or CobB-deletion in an E. coli led to elevated acetylation levels of AlaRS K73Ac and strongly reduced alanylation activities. We assumed that alanylation by AlaRS is affected by K73 acetylation, and the modification is sensitive to CobB deacetylase in vivo. We also showed that E. coli expresses two CobB isoforms (CobB-L and CobB-S) in vivo. CobB-S displayed the deacetylase activity of the AlaRS K73Ac variant in vitro. Our results imply a potential regulatory role for lysine acetylation in controlling the activity of aaRSs and protein synthesis.
The Epidemiology, Cost, and Occupational Context of Spinal Injuries Sustained While ‘Working for Income’ in NSW: A Record-Linkage Study
Authors: Sharwood Lisa N. , Mueller Holger , Ivers Rebecca Q. , Vaikuntam Bharat , Driscoll Tim , Middleton James W.
Published: September 2018

This study aimed to describe the epidemiological characteristics, the occupational context, and the cost of hospitalised work-related traumatic spinal injuries, across New South Wales, Australia. A record-linkage study of hospitalised cases of work-related spinal injury (ICD10-AM code U73.0 or workers compensation) was conducted. Study period 2013–2016. Eight hundred and twenty-four individuals sustained work-related spinal injuries; 86.2% of whom were males and had a mean age of 46.6 years. Falls led to 50% of the injuries; predominantly falls from building/structures, ladders or between levels. Falls occurred predominantly in the construction industry (78%). Transport crashes caused 31% of injuries and 24% in heavy vehicles. Half of all the transport injuries occurred ‘off road’. The external cause was coded as ‘non-specific work activity’ in 44.5% of cases; missing in 11.5%. Acute care bed days numbered at 13,302; total cost $19,500,000. High numbers of work-related spinal injuries occurred in the construction industry; particularly falling from a height. Off-road transport-related injuries were significant and likely unaddressed by ‘on-road’ prevention policies. Medical record documentation was insufficient in injury mechanism and context specificity. Workers in the construction industry or those using vehicles off-road were at high risk of spinal injury, suggesting inefficient systems approaches or ineffective prevention policies. Reducing the use of non-specific external cause codes in patients’ medical records would improve the measurement of policy effectiveness.
Motivations, Expectations and Experiences in Being a Mental Health Helplines Volunteer
Authors: Sundram Frederick , Corattur Thanikknath , Dong Christine , Zhong Kelly
Published: September 2018

Volunteers in non-government organisations are increasingly providing mental health support due to increasing demand and in the context of overstretched publicly-funded mental health services. This descriptive, cross-sectional study explored a knowledge gap in the literature of mental health telephone counselling by examining the motivation and retention determinants of helpline volunteers. In total, 25 participants were recruited across four focus groups and five individual interviews from a non-government organisation which provides a national phone counselling service to callers in New Zealand. Interviews were electronically recorded, transcribed and thematically analysed. Volunteers were found to have a high regard for their role and enjoyed many aspects including initial training, ongoing supports (formal/informal) and nature of the phone calls. However, organisational priorities/communication, disconnectedness, technological issues, lack of recognition and lack of a sense of belonging were reasons cited for intention to leave but previous mental health experiences, autonomy/flexibility, self-discovery/skills development and being there for someone else were key factors for volunteers to start and remain in their role. Understanding these crucial factors may help modulate volunteer satisfaction and retention in mental health organisations but may also potentially be relevant to other types of volunteer organisations.
Biofouling Mitigation by Chloramination during Forward Osmosis Filtration of Wastewater
Authors: Fujioka Takahiro , Nguyen Kha H. , Hoang Anh Tram , Ueyama Tetsuro , Yasui Hidenari , Terashima Mitsuharu , Nghiem Long D.
Published: September 2018

Pre-concentration is essential for energy and resource recovery from municipal wastewater. The potential of forward osmosis (FO) membranes to pre-concentrate wastewater for subsequent biogas production has been demonstrated, although biofouling has also emerged as a prominent challenge. This study, using a cellulose triacetate FO membrane, shows that chloramination of wastewater in the feed solution at 3–8 mg/L residual monochloramine significantly reduces membrane biofouling. During a 96-h pre-concentration, flux in the chloraminated FO system decreased by only 6% and this flux decline is mostly attributed to the increase in salinity (or osmotic pressure) of the feed due to pre-concentration. In contrast, flux in the non-chloraminated FO system dropped by 35% under the same experimental conditions. When the feed was chloraminated, the number of bacterial particles deposited on the membrane surface was significantly lower compared to a non-chloraminated wastewater feed. This study demonstrated, for the first time, the potential of chloramination to inhibit bacteria growth and consequently biofouling during pre-concentration of wastewater using a FO membrane.
Speciation Variation and Comprehensive Risk Assessment of Metal(loid)s in Surface Sediments of Intertidal Zones
Authors: Liang Baocui , Qian Xiao , Peng Shitao , Liu Xinhui , Bai Lili , Cui Baoshan , Bai Junhong
Published: September 2018

Speciation variation and comprehensive risk assessment of metal(loid)s (As, Cd, Cr, Cu, Mn, Ni, Pb and Zn) were investigated in surface sediments from the intertidal zones of the Yellow River Delta, China. Results showed that only the concentrations of As, Cd and Pb were significantly different between April and September (p < 0.01). In April, the residual fraction (F4) was predominant for As, Cr, Cu, Ni and Zn. However, the exchangeable and carbonate-associated fraction (F1) was dominant for Cd averaging 49.14% indicating a high environmental risk. In September, the F4 fraction was predominant and the F1 fraction was very low for most metal(loid)s except Cd and Mn. The geo-accumulation index (Igeo), the F1 fraction and potential ecological risk index (PERI) of most metal(loid)s were relatively low in surface sediments for both seasons. But Pb, As and Ni were between the threshold effect level (TEL)and the probable effect level (PEL) for 66.67%, 83.33% and 91.67% in April and As and Ni were between TEL and PEL for 41.67% and 91.67%, which indicated that the concentration of them was likely to occasionally exhibit adverse effects on the ecosystem. Although the Igeo, the F1 fraction or PERI of Cd in both seasons was higher at some sites, the results of sediment quality guidelines (SQGs) indicated that the biological effects of Cd were rarely observed in the studied area.
Factors Affecting Sick Leave Duration for Non-Work-Related Temporary Disabilities in Brazilian University Public Servants
Authors: Dias Adriano , Gómez-Salgado Juan , Bernardes João Marcos , Ruiz-Frutos Carlos
Published: September 2018

Sickness absenteeism in public institutions compromises the execution of services, and may also generate direct impacts on the population that receives coverage. To determine if sick leave duration for temporary disabilities is associated with non-work-related illnesses (NWRI), a historical cohort study was carried out of workers at a Brazilian University. The Charlson Comorbidity Index (CCI) was obtained from the most prevalent diagnoses in each expert examination and from the corresponding days of sick leave per episode, adjusting simple and multiple Cox regression models. As a result, 70% of the NWRI temporary disabilities were due to depressive disorders, convalescence, and dorsalgia with a sick leave duration between 4 and 320 days. The factors of protection for sick leave durations until the rehabilitation were non-insulin-dependent diabetes mellitus and hypertension. Long-term sick leaves were observed in the cases that required rehabilitation of those workers diagnosed with recurrent depressive disorders, conjunctivitis, acute sinusitis, skin disorders, calculus of kidney and ureter, abdominal and pelvic pain, and same-level fall accidents. It is also worth noting that even in a disease that can justify long-term sick leaves, such as breast cancer, the duration may be shorter according to the worker’s capacity and self-efficacy.
The Economic Impact of Herpes Zoster Vaccine Disparities in Elderly United States Blacks
Authors: Wingate La’Marcus T. , Stubbs Keisha , Ahmed Iman , Mayaka Rachel K. , Maneno Mary K. , Ettienne Earl , Elekwachi Oluchi , Clarke-Tasker Veronica
Published: September 2018

There are persistent disparities with regard to receipt of herpes zoster vaccine among elderly blacks, but no data is available regarding the public health or economic impact of these disparities. A decision tree was constructed with multiple Markov nodes in order to estimate the preventable cases of herpes zoster occurring among elderly blacks due to disparities in receipt of herpes zoster vaccine and to quantify the economic costs associated with these disparities. The model was constructed to examine the number of herpes zoster cases occurring among elderly blacks from the age of 60 to 84 over a 20 year period and also calculated costs due to herpes zoster complications and lost productivity. Achievement of health equity would prevent over 34,500 cases of herpes zoster from occurring in the future and avert over $180 million in lost productivity and treatment costs as a result of these cases of herpes zoster. These results help to show that thousands of cases of herpes zoster could be prevented if blacks were vaccinated at the same frequency as whites and help to show the benefit of implementing viable strategies to achieving this goal.
Risk of Exclusion in People with Disabilities in Spain: Determinants of Health and Poverty
Authors: Belzunegui-Eraso Angel , Pastor-Gosálbez Inma , Puig-Andreu Xavier , Valls-Fonayet Francesc
Published: September 2018

In this paper, we analyze data from the 2012 Encuesta de Integración Social y Salud (Social Integration and Health Survey) of the Instituto Nacional de Estadística (Spanish National Institute of Statistics) to obtain profiles created by combining disability, poverty and social exclusion. We hypothesize that the probability that people will experience social exclusion increases if they have a disability, chronic illness or limitation in conducting everyday activities, and that this probability is greater for women than for men. To conduct our analysis, we constructed a social exclusion model based on a series of social determinants that acts as a dependent variable. In this context, social exclusion is understood to go beyond the concept of financial poverty. We performed bivariate analyses, in which we calculated the Odds Ratios (OR) for certain variables considered to be predictors of social exclusion. We also performed a means comparison test and an ANOVA test to observe differences between individuals with recognized disability and those without. Finally, we conducted logistic regression analysis to determine which vulnerability profiles are most likely to experience a situation of social exclusion. We also discuss the limitations of our study, and suggest areas in, which the relationships between health, social exclusion and disability can be further investigated.
Do Occupational and Patient Safety Culture in Hospitals Share Predictors in the Field of Psychosocial Working Conditions? Findings from a Cross-Sectional Study in German University Hospitals
Authors: Wagner Anke , Hammer Antje , Manser Tanja , Martus Peter , Sturm Heidrun , Rieger Monika A.
Published: September 2018

Background: In the healthcare sector, a comprehensive safety culture includes both patient care-related and occupational aspects. In recent years, healthcare studies have demonstrated diverse relationships between aspects of psychosocial working conditions, occupational, and patient safety culture. The aim of this study was to consider and test relevant predictors for staff’s perceptions of occupational and patient safety cultures in hospitals and whether there are shared predictors. From two German university hospitals, 381 physicians and 567 nurses completed a questionnaire on psychosocial working conditions, occupational, and patient safety culture. Two regression models with predictors for occupational and patient safety culture were conceptually developed and empirically tested. In the Occupational Safety Culture model, job satisfaction (β = 0.26, p ≤ 0.001), work‒privacy conflict (β = −0.19, p ≤ 0.001), and patient-related burnout (β = −0.20, p ≤ 0.001) were identified as central predictors. Important predictors in the Patient Safety Culture model were management support for patient safety (β = 0.24, p ≤ 0.001), supervisor support for patient safety (β = 0.18, p ≤ 0.001), and staffing (β = 0.21, p ≤ 0.001). The two models mainly resulted in different predictors. However, job satisfaction and leadership seem to play an important role in both models and can be used in the development of a comprehensive management of occupational and patient safety culture.
The Effects of an Urban Forest Health Intervention Program on Physical Activity, Substance Abuse, Psychosomatic Symptoms, and Life Satisfaction among Adolescents
Authors: Tesler Riki , Plaut Pnina , Endvelt Ronit
Published: September 2018

Background: At-risk adolescents have been defined as youth who are or might be in physical, mental, or emotional danger. An Urban Forest Health Intervention Program (UFHIP) was formed at a center for at-risk adolescents in Israel, in order to promote physical activity and reduce risky behavior. Objective: To evaluate the intervention’s effect on physical activity, smoking, alcohol consumption, psychosomatic symptoms, and life satisfaction. Methods: From 2015 to 2016, at-risk youth were nonrandomly selected to participate in the UFHIP. Questionnaires were administered to both intervention and control groups before and after the intervention. Univariate and multivariable analyses evaluated the intervention’s effect. Results: The study participants (n = 53) showed 0.81 more sessions per week of 60 min of physical activity than did the control group (n = 23; p = 0.003). Among the intervention group, smoking frequency reduced from a mean of 2.60 (SD = 1.30) to 1.72 (SD = 1.08), whereas that in the control group increased from 3.17 (1.03) to 3.39 (1.03). In both groups, there was a reduction in alcohol consumption, with a greater change among intervention participants: −1.08 (SD = 1.30), compared with −0.09 (SD = 1.79) in the control group. Conclusions: Findings indicate that the environmental intervention was efficacious in increasing physical activity and reducing risky behaviors among youth. The effectiveness of this intervention among larger samples is warranted in future prospective studies.
Adverse Childhood Experiences in Children with Intellectual Disabilities: An Exploratory Case-File Study in Dutch Residential Care
Authors: Vervoort-Schel Jessica , Mercera Gabriëlle , Wissink Inge , Mink Emmelie , Van der Helm Peer , Lindauer Ramón , Moonen Xavier
Published: September 2018

Adverse Childhood Experiences (ACEs) are negative childhood events occurring in a child’s family or social environment, that may cause harm or distress. Children with intellectual disabilities (ID) and their families are underrepresented in international ACEs research, while current insights can also contribute to the improvement of their health and well-being. Deficiencies in intellectual and adaptive functioning and living circumstances can increase their vulnerability to adversities. In the present exploratory study 69 case-files of children referred to a Dutch national center for residential youth care for children with ID were analyzed to assess the prevalence and associations of ACEs. It was found that almost half (49.3%) of the children experienced 2 ACEs from the original ACEs framework or more (M (mean) = 2.1; SD (standard deviation) = 1.8) and that the number of ACEs in children was related to the presence of ACEs in parents. Both child and parental ACEs were also related to attachment- and trauma- and stressor-related disorders. Finally, living circumstances and multiple ACEs from the expanded ACEs framework, especially related to parental characteristics, were found to be related to ACEs in children with ID. This implicates the importance of a transgenerational approach when further investigating the impact of ACEs on mental and physical health in children with ID (intellectual disabilities).
Hazardous Drinking among Students over a Decade of University Policy Change: Controlled Before-and-After Evaluation
Authors: Kypri Kypros , Maclennan Brett , Cousins Kimberly , Connor Jennie
Published: September 2018

Background: Responding to high levels of alcohol-related harm among students, a New Zealand university deployed a security and liaison service, strengthened the Student Code of Conduct, increased its input on the operation of alcohol outlets near campus, and banned alcohol advertising on campus. We estimated the change in the prevalence of alcohol consumption patterns among students at the university compared with other universities. Methods: We conducted a controlled before-and-after study with surveys in residential colleges at the target university in 2004 and 2014, and in random samples of students at the target university and three control universities in 2005 and 2013. The primary outcome was the prevalence of recent intoxication, while we analysed drinking per se and drinking in selected locations to investigate mechanisms of change. Results: The 7-day prevalence of intoxication decreased from 45% in 2004 to 33% in 2014 (absolute difference: 12%; 95% CI: 7% to 17%) among students living in residential colleges, and from 40% in 2005 to 26% in 2013 (absolute difference: 14%; 95% CI: 8% to 20%) in the wider student body of the intervention university. The intervention effect estimate, representing the change at the intervention university adjusted for change at other universities (aOR = 1.30; 95% CI: 0.89 to 1.90), was consistent with a benefit of intervention but was not statistically significant (p = 0.17). Conclusion: In this period of alcohol policy reform, drinking to intoxication decreased substantially in the targeted student population. Policy reforms and coincidental environmental changes may each have contributed to these reductions.
Collective Efficacy: Development and Validation of a Measurement Scale for Use in Public Health and Development Programmes
Authors: Delea Maryann G. , Sclar Gloria D. , Woreta Mulat , Haardörfer Regine , Nagel Corey L. , Caruso Bethany A. , Dreibelbis Robert , Gobezayehu Abebe G. , Clasen Thomas F. , Freeman Matthew C.
Published: September 2018

Impact evaluations of water, sanitation, and hygiene interventions have demonstrated lower than expected health gains, in some cases due to low uptake and sustained adoption of interventions at a community level. These findings represent common challenges for public health and development programmes relying on collective action. One possible explanation may be low collective efficacy (CE)—perceptions regarding a group’s ability to execute actions related to a common goal. The purpose of this study was to develop and validate a metric to assess factors related to CE. We conducted this research within a cluster-randomised sanitation and hygiene trial in Amhara, Ethiopia. Exploratory and confirmatory factor analyses were carried out to examine underlying structures of CE for men and women in rural Ethiopia. We produced three CE scales: one each for men and women that allow for examinations of gender-specific mechanisms through which CE operates, and one 26-item CE scale that can be used across genders. All scales demonstrated high construct validity. CE factor scores were significantly higher for men than women, even among household-level male-female dyads. These CE scales will allow implementers to better design and target community-level interventions, and examine the role of CE in the effectiveness of community-based programming.
User-Centred Healing-Oriented Conditions in the Design of Hospital Environments
Authors: Dovjak Mateja , Shukuya Masanori , Krainer Aleš
Published: September 2018

Design approaches towards energy efficient hospitals often result in a deteriorated indoor environmental quality, adverse health and comfort outcomes, and is a public health concern. This research presents an advanced approach to the design of a hospital environment based on a stimulative paradigm of healing to achieve not only healthy but also comforting conditions. A hospital room for severely burn patient was considered as one of the most demanding spaces. The healing environment was designed as a multi-levelled, dynamic process including the characteristics of users, building and systems. The developed integral user-centred cyber-physical system (UCCPS) was tested in a test room and compared to the conventional system. The thermodynamic responses of burn patients, health care worker and visitor were simulated by using modified human body exergy models. In a healing environment, UCCPS enables optimal thermal balance, individually regulated according to the user specifics. For burn patient it creates optimal healing-oriented conditions with the lowest possible human body exergy consumption (hbExC), lower metabolic thermal exergy, lower sweat exhalation, evaporation, lower radiation and convection. For healthcare workers and visitors, thermally comfortable conditions are attained with minimal hbExC and neutral thermal load on their bodies. The information on this is an aid in integral hospital design, especially for future extensive renovations and environmental health actions.
MicroRNA-204 Is Necessary for Aldosterone-Stimulated T-Type Calcium Channel Expression in Cardiomyocytes
Authors: Koyama Riko , Mannic Tiphaine , Ito Jumpei , Amar Laurence , Zennaro Maria-Christina , Rossier Michel , Maturana Andrés
Published: September 2018

Activation of the mineralocorticoid receptor (MR) in the heart is considered to be a cardiovascular risk factor. MR activation leads to heart hypertrophy and arrhythmia. In ventricular cardiomyocytes, aldosterone induces a profound remodeling of ion channel expression, in particular, an increase in the expression and activity of T-type voltage-gated calcium channels (T-channels). The molecular mechanisms immediately downstream from MR activation, which lead to the increased expression of T-channels and, consecutively, to an acceleration of spontaneous cell contractions in vitro, remain poorly investigated. Here, we investigated the putative role of a specific microRNA in linking MR activation to the regulation of T-channel expression and cardiomyocyte beating frequency. A screening assay identified microRNA 204 (miR-204) as one of the major upregulated microRNAs after aldosterone stimulation of isolated neonatal rat cardiomyocytes. Aldosterone significantly increased the level of miR-204, an effect blocked by the MR antagonist spironolactone. When miR-204 was overexpressed in isolated cardiomyocytes, their spontaneous beating frequency was significantly increased after 24 h, like upon aldosterone stimulation, and messenger RNAs coding T-channels (CaV3.1 and CaV3.2) were increased. Concomitantly, T-type calcium currents were significantly increased upon miR-204 overexpression. Specifically repressing the expression of miR-204 abolished the aldosterone-induced increase of CaV3.1 and CaV3.2 mRNAs, as well as T-type calcium currents. Finally, aldosterone and miR-204 overexpression were found to reduce REST-NRSF, a known transcriptional repressor of CaV3.2 T-type calcium channels. Our study thus strongly suggests that miR-204 expression stimulated by aldosterone promotes the expression of T-channels in isolated rat ventricular cardiomyocytes, and therefore, increases the frequency of the cell spontaneous contractions, presumably through the inhibition of REST-NRSF protein.
Reactivation of Latent Epstein-Barr Virus: A Comparison after Exposure to Gamma, Proton, Carbon, and Iron Radiation
Authors: Mehta Satish , Bloom David , Plante Ianik , Stowe Raymond , Feiveson Alan , Renner Ashlie , Dhummakupt Adit , Markan Dhruv , Zhang Ye , Wu Honglu , Scoles Blaire , Cohen Jeffrey , Crucian Brian , Pierson Duane
Published: September 2018

Among the many stressors astronauts are exposed to during spaceflight, cosmic radiation may lead to various serious health effects. Specifically, space radiation may contribute to decreased immunity, which has been documented in astronauts during short- and long-duration missions, as evidenced by several changes in cellular immunity and plasma cytokine levels. Reactivation of latent herpes viruses, either directly from radiation of latently infected cells and/or from perturbation of the immune system, may result in disease in astronauts. Epstein‒Barr virus (EBV) is one of the eight human herpes viruses known to infect more than 90% of human adults and persists for the life of the host without normally causing adverse effects. Reactivation of several latent viruses in astronauts is well documented, although the mechanism of reactivation is not well understood. We studied the effect of four different types of radiation, (1) 137Cs gamma rays, (2) 150-MeV protons, (3) 600 MeV/n carbon ions, and (4) 600 MeV/n iron ions on the activation of lytic gene transcription and of reactivation of EBV in a latently infected cell line (Akata) at doses of 0.1, 0.5, 1.0, and 2.0 Gy. The data showed that for all doses used in this study, lytic gene transcription was induced and median viral loads were significantly higher for all types of radiation than in corresponding control samples, with the increases detected as early as four days post-exposure and generally tapering off at later time points. The viability and size of EBV-infected Akata cells were highly variable and exhibited approximately the same trend in time for all radiation types at 0.1, 0.5, 1.0, and 2.0 Gy. This work shows that reactivation of viruses can occur due to the effect of different types of radiation on latently infected cells in the absence of changes or cytokines produced in the immune system. In general, gamma rays are more effective than protons, carbon ions, and iron ions in inducing latent virus reactivation, though these high-energy particles did induce more sustained and later reactivation of EBV lytic gene transcription. These findings also challenge the common relative biological effectiveness concept that is often used in radiobiology for other end points.
Correlation Tracking via Self-Adaptive Fusion of Multiple Features
Authors: Chen Zhi , Liu Peizhong , Du Yongzhao , Luo Yanmin , Zhang Wancheng
Published: September 2018

Correlation filter (CF) based tracking algorithms have shown excellent performance in comparison to most state-of-the-art algorithms on the object tracking benchmark (OTB). Nonetheless, most CF based tracking algorithms only consider limited single channel feature, and the tracking model always updated from frame-by-frame. It will generate some erroneous information when the target objects undergo sophisticated scenario changes, such as background clutter, occlusion, out-of-view, and so forth. Long-term accumulation of erroneous model updating will cause tracking drift. In order to address problems that are mentioned above, in this paper, we propose a robust multi-scale correlation filter tracking algorithm via self-adaptive fusion of multiple features. First, we fuse powerful multiple features including histogram of oriented gradients (HOG), color name (CN), and histogram of local intensities (HI) in the response layer. The weights assigned according to the proportion of response scores that are generated by each feature, which achieve self-adaptive fusion of multiple features for preferable feature representation. In the meantime the efficient model update strategy is proposed, which is performed by exploiting a pre-defined response threshold as discriminative condition for updating tracking model. In addition, we introduce an accurate multi-scale estimation method integrate with the model update strategy, which further improves the scale variation adaptability. Both qualitative and quantitative evaluations on challenging video sequences demonstrate that the proposed tracker performs superiorly against the state-of-the-art CF based methods.
Investigation of the Reduction of a Molybdenum/Iron Molecular Nanocluster Single Source Precursor
Authors: Esquenazi Gibran L. , Barron Andrew R.
Published: September 2018

The thermolysis of the polyoxometalate cluster [HxPMo12O40⊂H4Mo72Fe30(O2CMe)15O254(H2O)90−y(EtOH)y] (1) under air, argon, and reducing conditions (5%, 10%, 50% H2 with Ar balance) has been investigated. The resulting products have been characterized by XRD, SEM, and EDX analysis. Thermolysis in air at 1100 °C yields predominantly Fe2O3, due to sublimation of the molybdenum component; however, under Ar atmosphere, the mixed metal oxide (Fe2Mo3O8) is formed along with Mo and MoO2. Introduction of 5% H2 (1100 °C) results in the alloy Fe2Mo3 in addition to Fe2Mo3O8 and Mo; in contrast, reduction at a lower temperature (900 °C) yields the carbide (Fe3Mo3C) and the analogous oxide (Fe3Mo3O), suggesting that these are direct precursors of Fe2Mo3. Increasing the H2 concentration (10%) promotes carbide rather than oxide formation (Fe3Mo3C and Mo2C), until alloy formation (Fe7.92Mo5.08) predominates under 50% H2 at 1200 °C. The effect of temperature and H2 concentration on the composition, grain size, and morphology has been investigated by EDX, SEM, and XRD. The relationship of the composition of 1 (i.e., Fe:Mo = 30:84) with the product distribution is discussed.