bluuebunny/crossref_metadata_2025 huggingface dataset:
Is Religion Natural? Response to David Fergusson
Authors: Ellis Fiona
Published: August 2024

This response to the 2024 Boyle Lecture takes David Fergusson’s lecture “Is Religion Natural?” as a starting point from which to discuss some of the philosophical issues that arise in this context. It raises the question of how we are to think about the limits of the natural, expresses some doubts about the explanatory pretensions of cognitive science of religion, and draws out the implications for the topic at hand, drawing upon an expansive naturalist framework.
Association of pre-diabetes with increased obesity and depression in older male and female: A secondary analysis of the Korea National Health and Nutrition Examination Survey 2020
Authors: Lee Heashoon
Published: August 2024

Purpose: This study aimed to investigate the association among pre-diabetes, increased obesity, and depression in Korean older men and women. Methods: Data of 1,005 participants (≥65 years) were extracted from the Korea National Health and Nutrition Examination Survey (KNHANES) VIII-2, 2020. A complex sampling design was adopted to reflect stratification, clustering, and weights. Data were analyzed using t-test, Rao-Scott chi-square test, and simple and multiple logistic regression. In predicting the risk factors for pre-diabetes, after adjusting, multiple logistic regression analysis was performed to confirm the relative contribution of each predictor variable. Results: Body mass index, waist circumference (WC), and incidence of depression were higher in the pre-diabetes group than in the normal group. According to the simple logistic regression analyses, in men, the odds ratio (OR) of pre-diabetes increased by 1.73, 2.25, and 2.53 for obesity (25.0~29.9 kg/m2), high obesity (≥30.0 kg/m2), and abdominal obesity (AO) (WC≥90 cm), respectively. In women, the OR of pre-diabetes increased by 2.15, 2.30, and 3.12 for high obesity, AO (WC≥85 cm) and depression diagnosis, respectively. In the adjusted analysis, in men, the adjusted odds ratio (AOR) of pre-diabetes increased by 2.73 and 1.97 for high obesity and AO (WC≥90 cm), respectively. In women, the AOR for pre-diabetes increased by 3.74 and 2.19 for depression diagnosis and no treatment for depression, respectively. Conclusion: This study provides evidence that interventions for obesity and depression should be included differently in pre-diabetes management programs for older men and women.
Effects of human rights sensitivity and perception of elder abuse on intention to intervene in elder abuse by workers in home welfare facilities and medical welfare facilities for older adults: A cross-sectional correlation study
Authors: Lee Yoo Jin , Ha Ju Young
Published: August 2024

Purpose: This study examined the effects of long-term care worker’s human rights sensitivity and perceptions of elder abuse on their intentions to intervene in elder abuse. Methods: This study adopted a descriptive design. Data accrued from 120 Workers (nurses, nurse assistants, and care workers) in Home Welfare Facilities and Medical Welfare Facilities for Older Adults using a convenience sampling method. The collected data were analyzed using the SPSS 25.0 software package. Results: Perception of elder abuse was analyzed to explain 30.0% of the intention to intervene in elder abuse. The higher the perception of elder abuse, the higher the intention to intervene in elder abuse (β=.32, p<.001). Conclusion: These results highlight that the higher the human rights sensitivity and awareness of elder abuse, the higher the intention to intervene in elder abuse. Awareness of elder abuse was found to be the only factor influencing the intention to intervene in elder abuse.
Ortaokul ve Lise Öğrencilerinin Okul Aidiyeti Duygusu Üzerine Fenomenolojik Bir Çalışma
Authors: Kalkan Çelik Canan , Sezgin Ferudun
Published: August 2024

Bu çalışmanın amacı okul aidiyeti olgusunu bütüncül bir yaklaşımla inceleyerek ortaokul ve lise öğrencilerinin duygu, düşünce ve görüşleri bağlamında çok yönlü bir değerlendirme sunmaktır. Çalışma nitel araştırma temelinde ve fenomenoloji deseninde tasarlanmıştır. Katılımcılar, 2023-2024 eğitim-öğretim yılında Ankara ili merkez ilçelerinde öğrenim görmekte olan 20 ortaokul ve lise öğrencisinden oluşmaktadır. Katılımcıların belirlenmesinde amaçlı örnekleme ve maksimum çeşitlilik yöntemleri kullanılmıştır. Araştırmanın verileri yarı yapılandırılmış görüşme formu ile toplanmıştır. Veriler betimsel analiz yöntemi kullanılarak çözümlenmiştir. Araştırma sonucunda öğrencilerin çoğunun kendilerini bulundukları okula ait hissettikleri belirlenmiştir. Öğrencilerin okul aidiyetleri üzerinde okulda öğretmenleri, akranları ve yöneticilerden gördükleri değer, destek ve başarıların teşvik edilmesinin etkili olduğu belirlenmiştir. Öğretmenlerin iletişim tarzları ve kullandıkları öğretim yöntem teknikler ve materyaller öğrencilerin okul aidiyetlerini etkilemektedir. Öğrencilerin çoğu bulundukları okulda öğrenciliği devam ettirmek istemektedir. Öğrenciler, okul aidiyetlerine okulu benimseme, okulda tanınma, gurur duyma ve güvende hissetme anlamlarını yüklemektedir. Öğrencilerin okul aidiyetlerinde, okulda bulunan yetişkinler ve akranlarla ilişkilerin önemi düşünüldüğünde, öğrencilere yönelik akran ve sosyal beceriler eğitimlerinin yapılması önerilmektedir. Öğrencilerin birlikte çalışabilecekleri iş birlikli öğrenme yöntemlerinin kullanılması ve proje çalışmalarına önem verilmesi önerilmektedir.
Predictive and prognostic value of preoperative pan-immune-inflammation value in patients with locally advanced rectal cancer
Authors: Shen Peipei , Xu Yu , Zhu Jiahao , Qian Danqi , Yang Bo , Mao Yong , Ji Shengjun , Gu Ke , Zhao Yutian
Published: August 2024

This study aimed to investigate the prognostic value of the pan-immune-inflammation value (PIV) in patients with locally advanced rectal cancer (LARC) who received neoadjuvant chemoradiotherapy (nCRT) followed by total mesorectal excision. We retrospectively collected and analyzed the clinicopathological data of 215 resected LARC patients. X-tile software was used to determine the optimal threshold value for PIV in predicting overall survival (OS). The predictive ability of PIV for pathological complete regression (pCR), OS, and disease-free survival (DFS) was evaluated and compared with other inflammation markers. Univariate and multivariate logistic regression analyses for pCR and Cox regression analyses for OS and DFS were conducted. The optimal threshold value for PIV was determined to be 454.7 based on the X-tile software. Patients were then categorized into low (≤ 454.7) and high (> 454.7) PIV groups comprising 153 and 62 patients, respectively. PIV demonstrated superior predictive ability for pCR, OS, and DFS compared to other inflammation markers. LARC patients with low PIV had significantly higher pCR (P = 0.029), OS (P = 0.002), and DFS (P = 0.001) rates compared to those with high PIV. Multivariate regression analysis identified PIV as an independent prognostic factor for pCR (odds ratio = 0.32; 95% confidence interval [CI], 0.10-0.80; P = 0.014), OS (hazard ratio = 3.08; 95% CI, 1.77-5.35; P = 0.001), and DFS (hazard ratio = 2.53; 95% CI, 1.58-4.06; P = 0.002). This study confirmed that preoperative PIV could serve as a useful independent prognostic factor in LARC patients treated with nCRT.
JAX-Sen: Collection and shipment of specimen for Bulk RNA-sequencing (Bulk RNA-seq) v2
Authors: Robinson Laura
Published: August 2024

These samples are part of the JAX-Sen project in the SenNet Consortium. Here we provide details on specimen collection and shipment to the Robson laboratory at The Jackson Laboratory for Genomic Medicine (JAX-GM) in Farmington, CT for its processing for Bulk RNA-sequencing (Bulk RNA-seq).
Preparation, storage and use of the positive and negative controls for DDNS v2
Authors: Akello Joyce , Majumdar Manasi , Shaw Alex , Troman Catherine , Bujaki Erika , Martin Javier , Grassly Nick
Published: August 2024

This protocol describes the laboratory process for the use of run controls (positive and negative controls)for performing direct detection of poliovirus by nanopore sequencing (DDNS assay). The protocol outlines the key steps of how and when to use the run controls for DDNS assay including preparation, and storage. The run controls are used to demonstrate that the entire DDNS workflow starting from RNA extraction to obtaining a sequence is successfully performed. Positive control (Coxsackievirus A20) – Supplied by MHRA, contact Dr. Erika Bujaki at erika.bujaki@mhra.gov.uk. and Dr. Thomas Wilton at thomas.wilton@mhra.gov.uk. and copy Dr. Javier Martin at javier.martin@mhra.gov.uk).
Laser Capture Microdissection Assisted Spatial Proteomics v1
Authors: Wang Zhenda , Chen Yuexin , Gote-Schniering Janine , Schiller Herbert
Published: August 2024

This protocol was used to generate spatial proteomics dataset from pediatric lung, as a part of the CZI-MPII project. For more information: Mapping the Pediatric Inhalation Interface: Nose, Mouth, and Airways, - Chan Zuckerberg Initiative
Working Couple’s Communication Patterns In Maintaining Family Harmony
Authors: Tri Ambarwati Intan , Andriani Fizzy , Nilamsari Natalina
Published: August 2024

For married couples who both works are vulnerable to conflict between them. Effective communication is needed to prevent this from happening. This research aims to find out how the communication patterns of husband-and-wife couples work together to maintain family harmony. This research is a qualitative descriptive study involving four husband and wife couples who work in Jakarta. This research uses the Coordinated Management of Meaning Theory with the Family Harmony Aspect approach. Data was collected through interviews. The research results show that there are married couples who can still understand each other, even though they lack communication and are unable to express affection for their partner, such as by giving compliments. There are also two married couples who spend a lot of time with their partners, but even though other married couples admit that they rarely spend time alone with their partners, they still have a sense of mutual understanding. Communication between partners, mutual understanding and how they spend time together, are important aspects in maintaining family harmony. The implications of this research can be applied to premarital counseling, especially for job applicant couples, to minimize the risk of divorce due to disharmony.
PENGARUH KONSENTRASI PUPUK ORGANIK CAIR (POC) BONGGOL PISANG TERHADAP PERTUMBUHAN DAN HASIL BEBERAPAVARIETAS TANAMAN TOMAT (Lycopersicum esculentum Mill.)
Authors: Haekal Muhammad , Marliah Ainun , Hayati Rita
Published: August 2024

Abstract. Tomatoes are one type of horticultural plant that has its own charm because it has high economic value and is very promising. One of the efforts to increase the yield potential of tomato plants is by applying fertilizer. Fertilizer is a material added to growing media or plants to meet the nutritional needs of the plant for good growth. In addition to fertilization, increasing tomato production can also be increased by using appropriate varieties. The purpose of this study was to determine the concentration of liquid organic fertilizer and banana weevil species and the interaction of these two factors on tomato growth and yield. The study was conducted from August to December 2022 in Lampedaya village, Darussalam sub-district, Aceh Besar district and the Laboratory of Seed Science and Technology, Faculty of Agriculture, Syiah Kuala University. This study used a 4x3 factorial randomized block design (RBD) with 3 replications, resulting in 12 treatment combinations and 36 experimental units. There are 2 factors studied, namely the concentration of banana weevil liquid organic fertilizer and tomato varieties. The first factor is the concentration of banana weevil liquid organic fertilizer (P) consisting of 4 levels, namely P0 = Control, P1 = 25%, P2 = 50%, P3 = 75% and the second factor is variety (V) which consists of 2 levels, namely V1 = Servo F1, V2= Karina F1, V3= Jewel F1. The results showed that the POC of banana weevil had a very significant effect on fruit weight per fruit and had a significant effect on the number of fruit bunches. Tomato plant growth and yield were optimal at a banana weevil POC concentration of 75%. Tomato varieties have a very significant impact on plant height, flowering age, fruit weight per plant, number of fruits per bunch, fruit weight per fruit, yield potential of 30 HST and 45 HST. The tomato plant growth and yield are best with Servo F1 variety. There was a very significant interaction between banana weevil POC concentrations and several at 45 HST the highest was obtained in a combination of 50% concentration with Karina F1 variety. Keywords: Banana weevil POC concentration, varieties, tomatoes varieties on higher fruit weight obtained in a combination of 75% concentration with the Permata F1 variety, there was a significant interaction between banana weevil POC concentrations and several varieties on stem diameter.
Customer Variety-Seeking and Brand Switching Intention: An Exploration of the Mediating Role of Customer Engagement
Authors: Priscilla Lysandra , Rufaidah Popy
Published: August 2024

This study focuses on determining the impact of customer variety-seeking on brand switching intention by exploring the mediation role of customer engagement in streaming services in Indonesia. The data were gathered using a purposive sampling technique, and valid responses from 124 respondents were analyzed. The study results showed that customer variety-seeking significantly improves customer engagement. This study also found a non-significant direct effect of customer variety-seeking on brand switching intention and a negative significant effect of customer engagement on brand switching intention. In indirect relationships, customer engagement has a significant negative role in mediating customer variety-seeking and brand switching intentions. Aligned with social exchange theory, brand switching intention was found to be minimal since customer engagement is a significant mediator of customer variety-seeking and this switching. The findings have emphasized fostering customer engagement to increase customer retention.Keywords: Customer variety-seeking, Customer engagement, Brand switching intention, Social exchange theory
EVALUASI KINERJA SIMPANG BERSINYAL PADA SIMPANG LINCING, KABUPATEN BANYUWANGI MENGGUNAKAN SOFTWARE PTV VISSIM
Authors: Nirwana Kira Malik , Siswanto Henri , Pranoto Pranoto
Published: August 2024

Abstrak : Simpang Lincing merupakan salah satu simpang bersinyal di Kabupaten Banyuwangi yang ramai dan padat, serta sering terjadi kemacetan lalu lintas. Dengan terjadinya kemacetan, antrian kendaraan yang cukup panjang, serta tundaan kendaraan yang cukup lama mengakibatkan waktu perjalanan semakin bertambah dan biaya operasional kendaraan meningkat. Tujuan dari penelitian ini adalah mendeskripsikan kinerja simpang dan memberikan solusi alternatif untuk meningkatkan kinerja simpang Lincing. Metode pengumpulan data dilakukan dengan cara merekam pergerakan kendaraan dengan menggunakan alat perekam. Survei dilakukan selama 4 hari, yaitu pada hari Sabtu dan Minggu sebagai perwakilan hari libur, serta hari Senin dan Rabu sebagai perwakilan hari kerja, pada pukul 06.00 WIB – 09.00 WIB, 11.00 WIB – 14.00 WIB dan 16.00 WIB – 19.00 WIB. Analisa perhitungan yang digunakan adalah pemodelan simpang dengan software PTV Vissim. Hasil penelitian yang diperoleh ialah kinerja simpang metode vissim nilai tundaan 72,98 det/kend dengan tingkat pelayanan E. Solusi alternatif 1 adalah pelebaran jalan pada pendekat selatan dan barat, diperoleh hasil simulasi vissim dengan nilai tundaan 52,55 det/kend dengan tingkat pelayanan D. Solusi alternatif 2 adalah pemberlakukan belok kiri langsung pada pendekat barat, diperoleh hasil simulasi vissim dengan nilai tundaan sebesar 52,26 det/kend dengan tingkat pelayanan D. Solusi alternatif 3 yaitu dilakukannya pelebaran jalan pada pendekat selatan dan barat, dan juga pemberlakuan belok kiri langsung pada pendekat barat, diperoleh hasil simulasi vissim dengan nilai tundaan sebesar 34,58 det/kend dengan tingkat pelayanan C.
Awareness of cervical cancer among the undergraduate medical students of Churachandpur Medical College, Manipur, India
Authors: Sarda Devi Okram , Vashum Melody
Published: August 2024

Background: The incidence of cancer overall is in increasing trends all over the world cervical cancer is the only vaccine preventable cancer. India need robust screening and vaccination program and for this the medical students need to understand and learn about it. This study was done to explore knowledge of cervical cancer among the medical undergraduates so that teaching pedagogy can n be plan based on the previous knowledge of the students which will in turn result in providing better health services to our community.
Methods: The study was a cross-sectional observational study done at Imphal campus of Churachandpur Medical College on all 183 undergraduates medical graduates for duration of 1 month from May 15th, 2024, to June 15th, 2024.
Results: 6 out of 142 students (4%) % of the students have never heard of cancer cervix 10% didn’t know that cancer cervix is preventable, 8% didn’t know that early detection can be done, 24% did not know about cancer cervix screening, 32% have never heard of pap smear 11% have never heard of HPV vaccine 6% did not know that HPV vaccine can prevent cancer cervix and 35% did not know when is HPV vaccine given.
Conclusions: Our medical students are still lagging, and we have to work on providing and developing educational programs to improve the knowledge and awareness of cancer cervix.
An interesting case report on obstructed labour with prune belly syndrome
Authors: Somasundaran Aiswaria , Sandra K. Unni  , Naseema Beevi Ahmed Khan
Published: August 2024

Prune belly syndrome is a rare disorder of uncertain etiology characterized by a triad of deficient abdominal musculature, cryptorchidism and urinary tract abnormalities. This condition varies in its severity which makes diagnosis challenging during early antenatal ultrasound scan. 34-year-old G4P3L3 who was counselled for pregnancy termination at 20 weeks in view of multiple anomalies detected on antenatal ultrasound. At 34 weeks of gestation presented to our institution in active phase of labour and progressed to obstructed labour and was managed by ultrasound guided fetal abdominal tapping. We conclude that suspicion of such anomalies through an early antenatal scan require further follow-up with an experienced ultrasonographer and maternal–fetal medicine specialist for a decision to be made antenatally regarding the course of pregnancy and delivery management based on the severity of the condition in a tertiary center.
Prediction of severity of acute pancreatitis using neutrophil to lymphocyte ratio
Authors: Shrestha Ashish , Pradhananga Smeena , Shakya Niliza
Published: August 2024

Background: Patients with mild acute pancreatitis (AP) have mortality rates of less than 1% which increases up to 10% to 30% in severe AP (SAP). Early prediction of severity helps in complication prevention. Neutrophil lymphocyte ratio (NLR) could be simple, easy and cheap tool for predicting severity of AP in its early course.
Methods: This prospective, observational study included forty-five patients admitted over a period of six months from August 2020 to January 2021 with diagnosis of AP at Bir hospital. NLR was performed at the time of admission.
Results: The 22.2% patients had SAP with mean age of 45.6±14.73. It was common in male (60%) and the most common cause was gallstone. Etiology, BMI, neutrophilia, lymphopenia, SIRS scores were found to have statistically significant association to severity of AP. A cut off value of 4.49 was calculated for NLR for predicting severity of pancreatitis with sensitivity of 100%, specificity of 97.1%, PPV of 90.9 % and NPV of 100%. Mean NLR was 7.80±1.69 for mortality group.
Conclusions: NLR can be used as a simple, easy and inexpensive prognostic marker of severity of AP.
A diagnostic dilemma: enterolith formation secondary to stricture and subsequent bowel obstruction: a case report
Authors: Jadhav Pradnya S. , Hedawoo Jagadish B. , Changole Sanjay S. , Soni Mahesh K. , Lalwani Adarsh , Kamble Akhilesh
Published: August 2024

We report a case of a 67 years male patient who presented with complaints of pain in abdomen, loose motions since 3 months and distension of abdomen since 1 day. At the time of admission patient was vitally stable, with no history of vomiting and constipation. Plain x-ray abdomen erects showed evidence of approximately 4-5 radio opaque foreign bodies in the abdomen. Contrast Enhanced computed tomography (CECT) of abdomen revealed multiple ileal strictures with closed loop obstruction with large monoliths. Exploratory laparotomy confirmed 7 ileal strictures each 10 cm apart with proximal dilatation. Resection of ileal stricture was performed and ileoileal anastomosis done. The resected segment contained seven hard, black enteroliths.
Cervical extension of pancreatic pseudocyst an unusual entity
Authors: Charutha Roshil , Joshi Madhur Arun , Joshi Sampada
Published: August 2024

Pancreatic pseudocyst is a common complication that occurs following acute or chronic pancreatitis. Although the common location of pseudocyst is lesser sac, extension of pseudocyst can occur into mesentery, retroperitoneum, inguinal region, pleura and lung. Extension of pseudocyst into mediastinum and cervical spaces is extremely rare. Mediastinal extension of pseudocyst is a rare occurrence reported in fewer than 100 cases. Cervical extension of pseudocyst is even rarer. Due to the rarity of the condition, there is a lack of uniform treatment protocols which poses a challenge in the management of this condition. Here we report a rare case of bilateral cervical extension of ruptured pseudocyst and its management.
Utilizing calcium gluconate with low dose neostigmine to enhance neuromuscular recovery from non-depolarizing blockade: A prospective randomized control study
Authors: Sharma Kush , Singh Aparna , Bhalotra Anju Romina
Published: August 2024

Ionized calcium has a pivotal role to play in neuromuscular transmission. Co-administration of calcium gluconate may allow for tapering the dose of neostigmine used for neuromuscular reversal, thus minimizing adverse effects associated with it while also reducing the chances of residual neuromuscular blockade (NMB). This study aimed to assess the effectiveness of calcium gluconate upon co-administration with neostigmine in enhancing rate of neuromuscular recovery and reducing the incidence of postoperative residual curarization.

: This parallel group, double-blind randomized controlled study was conducted on 60 patients undergoing surgery at a tertiary care center. Patients in Group CN received 5 mg kg of 10% calcium gluconate with neostigmine while Group N received 5 ml 0.9% saline with neostigmine for reversal of NMB. Time from neostigmine administration to achieving a TOF ratio of ≥0.9 was taken as the primary outcome. Additional neostigmine requirement and symptoms of residual neuromuscular blockade (RNMB) in the post-anesthesia care unit (PACU) were considered as secondary outcomes.

A significant difference was found in the meantime taken to achieve TOF ratio ≥0.9 after giving reversal, taking 5.43 ±2.12 mins in Group CN and 8.49 ±4.72 mins in Group N (p = 0.001). Although in Group N, 13.33% patients showed signs of RNMB in PACU versus 3.33% patients in Group CN. This difference was not found to be clinically significant (p=0.081).

The findings of our study suggest that the administration of exogenous calcium may improve neuromuscular transmission even in normocalcemic patients. In conclusion, co-administration of calcium gluconate with low dose neostigmine helps in reducing neuromuscular recovery time in the early period of NMB reversal without incurring any significant disadvantages of administering higher doses of neostigmine.
Assessment of effect of two different doses of dexmedetomidine infusion on emergence agitation and quality of recovery after nasal surgery
Authors: Koshyari Harish Singh , Riar Harsimran Kaur , Jindal Parul , Agrawal Vinish Kumar
Published: August 2024

: To evaluate two different doses of dexmedetomidine infusion on emergence agitation and measurement of hemodynamics, bispectral index, cortisol levels, and quality of recovery in patients who underwent nasal surgery under general anaesthesia.

94 individuals of either sex between the ages of 18 and 65 who experienced nasal surgery under general anesthesia were split into two groups for this randomized experimental study. Before induction, each group received loading doses of dexmedetomidine (DEX) infusion at a rate of 1 µg/kg over a period of 10 minutes. Group B underwent a standard induction and then received an infusion of 0.4μg/kg/h of dexmedetomidine every hour until they were extubated, while group A received an infusion of 0.8μg/kg/h. Sevoflurane was employed for maintenance. During emergence, the frequency of agitation, cough hemodynamic parameters, and recovery traits were assessed. Patients received the Quality of Recovery (QoR-40) questionnaire 24 hours following surgery.

The hemodynamic reaction to laryngoscopy and intubation was blunted and the intubating circumstances were improved by both doses equally well. Group A's intraoperative mean PR and MAP were significantly (P<0.05) lower than group B's. Coughing was more common among the subjects in group A. A statistically significant difference was found between groups in comparing emergence agitation. Cortisol levels were significantly higher postoperatively in the 0.4µg/kg dose of dexmedetomidine 0.8µg/kg/ group (p=0.001). Global QoR-40 score at 24 h after surgery showed a better global recovery profile in group A.

:Although a greater dose of DEX may have more hemodynamic adverse effects, it may also reduce the incidence of emergent agitation, the surgical stress response, and a smoother recovery profile.
Anesthetic management in a rare case of clark-baraitser syndrome: Insights and challenges
Authors: Madhu Madhu , Bansal Teena , Yadav Nisha
Published: August 2024

Clark Baraitser syndrome is a rare autosomal dominant genetic disorder characterized by multiple congenital anomalies and distinctive facial features. These features, including a high arched palate, can complicate airway management. Anaesthetizing an intellectually disabled patient is a challenging task due to lack of communication and understanding, which makes perioperative evaluation difficult. The perioperative management of antiepileptic drug therapy is important for seizure control in these patients. This case report describes the anaesthetic management of 10-year-old child with Clark Baraitser syndrome with bilateral undescended testis posted for orchiopexy.
MARIO TEGUH'S RHETORICAL STYLE THROUGH YOUTUBE AND INSTAGRAM CHANNELS
Authors: Andriani Kiki , Malik Ibrahim
Published: August 2024

This research aims to analyze Mario Teguh's rhetorical style through YouTube and Instagram. The benefits of the research can provide a reference for motivators to use rhetorical style in public speaking. This research uses qualitative research with a discourse analysis approach. Data collection techniques using observation and documentation and validity techniques using source triangulation. Based on word choice, Mario Teguh uses official, unofficial, and conversational styles. Based on tone, he uses simple, medium, noble and powerful styles. Based on sentence structure using climax, anti-climax, parallelism, antithesis, and repetition. Based on voice style Mario Teguh uses a slow rate, pauses with the word "em", pitch with high and low tones. On the volume Mario Teguh shows soft and loud. Based on body posture shows a sitting position. Appearance and clothing Mario Teguh uses neat koko clothes. Facial expressions are smiling with attention to the audience. Hand movements are in accordance with the topic discussed. Eye gaze occasionally looks at the material and more often looks at the audience
Designing an Online Collaborative Exam:
Authors: Miller Mariel , Askari Safoura
Published: August 2024

The ability to collaborate online is an essential skill that allows learners to bring together diverse perspectives to deepen understanding regardless of physical location. As online learning and hybrid workplaces have become more prevalent since the COVID-19 global pandemic, the critical nature of this skill has become particularly relevant for post-secondary graduates. While exams are traditionally viewed as solitary endeavors, collaborative exams offer invaluable opportunities for learners to develop these skills. However, this form of collaborative assessment can be challenging for both learners and educators, and few studies offer guidance for the effective design of collaborative exams. As such, in this paper, we report on the design and implementation of a synchronous collaborative midterm exam in a large first-year undergraduate course. Specifically, we describe how we drew on a theoretical framework of self- and socially shared regulation of learning to design a three-phase exam fostering learners’ engagement in key processes of planning, strategic enactment, and reflection on collaboration processes and products. Finally, we discuss key considerations that arose during the design and implementation of the exam, including ensuring an emphasis on process and authenticity, ethical use of video, and equity of access.
Effect of Sleep Deprivation on the Performance of Pilots: A Systematic Review
Authors: Naseri Shahruz , Eslami Reza , Samadi Shahram , Hassanlouei Babak
Published: August 2024

Sleep deprivation negatively affects a person's emotions, cognition, and performance and ultimately reduces safety. The main purpose of this systematic review is to study and report the evidence on the effect of sleep deprivation on the performance of pilots. This systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. International databases including PubMed, Web of Science (WOS) and Scopus were considered for the search of English articles up to April of 2023. Keywords were sleep deprivation, pilot, flight, performance, airline, air force, flight safety, fatigue, pilot performance, flight performance, eye movement, workload, motion, visual, attention, errors, cognition, sleep quality, and circadian rhythm. In this systematic review, 12 studies consisting of 259 subjects remained. Most of the studies have reported the negative effects of sleep deprivation in a different way, and the decrease in performance was expressed as one of the important issues following sleep deprivation. As various studies show, any type of sleep deprivation in pilots can have negative effects on their performance, and this decrease in performance can have irreparable consequences.
Exploring Ethical Theories Among Medical Residents in Clinical Situations: A Cross-Sectional Study
Authors: Ebrahimi Sedigheh , Kamyab Amirhossein
Published: August 2024

Human beings are faced with numerous behavioral options in different situations, but they can only choose a limited number of them. Ethical beliefs, values, and principles guide individuals in decision-makings. This study focuses on medical residents' perspectives towards four ethical principles (Deontology, Utilitarianism, Virtue, and Principlism) in various clinical situations. This descriptive-analytical study was performed cross-sectional basis among a population of medical residents of Shiraz University of Medical Sciences. Data were gathered by multi-stage cluster sampling method using a researcher-made questionnaire including demographic information and five different clinical scenarios. The data were analyzed using the Chi-square test and descriptive and inferential statistics in SPSS22. The results of this study showed that there was no significant relationship between gender, specialty, year of study, and the four ethical principles mentioned in the participants. However, a significant correlation was observed between the types of scenarios and their alignment with a particular type of decision or ethical theory. The ethical philosophy of medical residents has been evolving gradually over time, even before entering the residency period. Therefore, focusing on practical ethics training and the commitment of residents to implementing the principles and values of professional ethics can shape the ethical philosophy of residents towards professional ethics and humanity.
Total Antioxidant Capacity, Salivary Catalase, and Superoxide Dismutase in Hashimoto's Thyroiditis Patients
Authors: Nosratzehi Shahin , Nosratzehi Mahin , Alijani Ebrahim , Payandeh Abolfazl , Nosratzehi Tahereh , Charvaei Abdulmannan
Published: August 2024

Hashimoto's thyroiditis (HT) is one of the common causes of hypothyroidism. Although various factors are involved in its development, recently the role of oxidative stress in its pathogenesis has been known. The present study aimed to investigate the level of total antioxidant capacity (TAC), catalase (CAT), and salivary superoxide dismutase (SOD) in patients with HT compared with the control group. The present case-control design included patients aged 18-80 years suffering from HT referred to the endocrine clinic. Eligible patients were selected by the available sampling method. Complete unstimulated saliva was collected under a rest state in a comfortable room between 10:00 AM and 12:00 AM and a checklist was used to collect data. The chi-square, t-test, and Mann-Whitney U tests were used for data analysis using SPSS 22 software. The mean age of the participants was 36.55±9.37 years (range: 20-56). The two groups were the same in terms of age and gender (P>0.05). The findings indicated that the difference in the means CAT between the two groups was 22.63 which was strongly and statistically significant (P<0.001). In this study, the level of TAC and SOD in Hashimoto's thyroid patients was decreased and the level of CAT was increased. These initial findings show that oxidative stress can be associated with Hashimoto's thyroid disease or the possibility of developing this disease increase.
Comparing the Efficacy of “Spray as You Go” Technique Versus Combined Airway Nerve Block and “Spray as You Go” as Topical Anesthesia During Flexible Bronchoscopy; a Double-Blinded Randomized Clinical Trial
Authors: Rafiee Effat , Paknejad Omalbanin , Eftekhar Negar , Salehi Oveis , Rashidi Parisa , Gholamzadeh Marsa , Asadi Gharabaghi Mehrnaz
Published: August 2024

Flexible bronchoscopy is employed to diagnose a range of respiratory disorders. Local airway anesthesia is mandatory to facilitate tracheal intubation. It is commonly done by injection of diluted lidocaine through working channel of bronchoscope via Spray-as-you-go (SAYGO) method. Other methods such as airway nerve block (ANB) by direct injection of lidocaine are also used to increase patient comfort. The aim of this study was to compare patient and physician satisfaction during bronchoscopy in two groups receiving SAGO alone versus combination of SAYGO and ANB. In a double-blinded randomized clinical trial, 68 patients undergoing bronchoscopy were divided into two groups. The first group received local anesthesia solely through the SAYGO method, while the second group received a combination of SAYGO and ANB. Both groups received intravenous sedation. The anesthesia level was assessed using Ramsay score. Patient and physician satisfaction with bronchoscopy was evaluated on a numeric scale of 1 to 5. Combination of ANB and SAYGO resulted in significantly higher satisfaction score both in physician [3.4±1.6 and 4.6±0.8] and patients [3.5±1.3 and 4.9±0.4] (P<0.001). Thirteen individuals (38.2%) in the SAYGO and four individuals (11.8%) in SAYGO+ANB experienced a drop in oxygen levels (P=0.023). Additionally, sedation levels (Ramsay sedation scale score) were significantly higher in the first group (4) compared to the second group (3) (P=0.001). Combining ANB with SAYGO resulted in higher patient and physician comfort during bronchoscopy in comparison to SAYGO alone with no increase in complications.
Investigating the Effect of Educational Film Presentation on the Anxiety Level of Mothers Visiting the Preoperative Anesthesia Clinic
Authors: Malekianzadeh Bita , Samimi Sade Saghar , Eslami Babak , Ostadalipour Abbas , Ariana Parastou , Nazari Nima
Published: August 2024

With the increasing number of pediatric surgeries and the transfer of caregiving roles to parents, appropriate preparation and reduction of their stress levels for proper care of children before and after surgery is essential. If parental anxiety can be reduced through various methods, not only can it improve parental performance and their comfort, but it can also prevent the impact of anxiety on the child. Therefore, we aimed to investigate the effect of educational film presentation on the anxiety level of mothers visiting the obstetric anesthesia clinic at the Children's Medical Center in 2020. This study was a randomized double-blind controlled trial conducted as an intervention. Sampling was done randomly, and the study population consisted of two groups of 38 individuals, whose children were candidates for MRI. The intervention group watched the educational film, while the second group served as the control group. Subsequently, their anxiety levels were assessed and compared using the Beck Anxiety Inventory. The data were entered into SPSS Ver. 21 software and analyzed accordingly. The mean age of mothers in this study was 33.41 years with a standard deviation of 7 years. The mean age of children was 3.79 years with a standard deviation of 3.4 years. Among the children, 30 were girls (39.5%) and 46 were boys (60.5%). The mean age of girls was 4.35 years with a standard deviation of 4.16 years, while the mean age of boys was 3.433 years with a standard deviation of 2.787 years. Overall, 39 participants (50.6%) watched the educational film, while 38 participants (49.4%) were in the control group. The mean score of anxiety level according to the Beck Anxiety Inventory (BAI) was 9.47 with a standard deviation of 9.77. The level of anxiety was significantly higher in the intervention group who watched the educational film compared to the control group (P=0.012). The results of the present study indicated that parental anxiety increased after watching the educational video on anesthesia methods. It is recommended that alternative strategies be considered for reducing parental anxiety in future studies.
Adverse Pregnancy Outcomes in Patients With Systemic Lupus Erythematosus: A Retrospective Cohort Study
Authors: Sadeghi Alireza , Mousavi Safieh , Rostami Mina , Hatami Robabeh , Karamitanha Farzaneh
Published: August 2024

Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease that may result in adverse pregnancy outcomes, posing a significant risk to both the mother and the fetus. The major purpose of the current study was to investigate the impact of SLE on the outcomes of pregnancy among women with SLE. This was a retrospective cohort study. Two groups of pregnant women, one with Systemic Lupus Erythematosus (SLE) and one without SLE, were included at the Gynecology and Obstetrics Clinic of Ayatollah Mousavi Hospital in Zanjan, Iran, from 2019 to 2020. Participants from both cohorts completed a checklist of study variables based on their medical records. The data were analyzed using binary logistic regression, chi-square test, analysis of variance, and independent samples t-test with SPSS software version 23. The research involved 400 pregnant women, with the mean age of the SLE and non-SLE groups being 36.68±4.90 and 29.46±6.56 years, respectively. The most prevalent adverse outcome was cesarean section (271 [67.8%]), significantly higher in the SLE group (54.5% vs. 10.0%, P=0.0001). The likelihood of experiencing spontaneous abortion, preterm labor, cesarean section, and LBW was increased by more than 6.5 times (odds ratio, 6.54; 95% CI, 2.22-19.27; P=0.001), 3.6 times (odds ratio, 3.67; 95% CI, 1.47-9.18; P=0.005), 18.9 times (odds ratio, 18.94; 95% CI, 6.46-55.49; P=0.0001), and 3 times (odds ratio, 3.04; 95% CI, 1.09-8.46; P=0.030) in individuals with SLE, respectively. Women with SLE have an increased likelihood of encountering spontaneous abortion, preterm labor, cesarean section, and delivering a low-birth-weight infant.
Malposition of Central Venous Pressure Catheter as a Rare Cause of Tricuspid Valve Prosthesis Malfunction: A Case Report
Authors: Behjati Mohaddeseh , Tohidi Fatemeh , Baharestani Bahador
Published: August 2024

Prosthetic valve malfunction is a hazardous clinical entity that needs early diagnosis and management. Hereby, we present a case of tricuspid valve (TV) malfunction due to interaction of central venous pressure (CVP) catheter with TV leaflets. Our case was a 38-year-old male who referred to our center with the diagnosis of TV malfunction. Confirming the diagnosis of TV malfunction, intravenous Heparin was initiated. Anticoagulation therapy was discontinued early due to the development of significant headache in the setting of subarachnoid hemorrhage. Due to contraindication of anticoagulation therapy, he underwent redo TV. On the 4th post-operative day, echocardiography examination illustrated significant increase in gradients of TV prosthesis. At this time, fluoroscopy depicted interaction of CVP catheter with TV leaflets due to its cardiac advancement resulted in fixed TV leaflets in semi-open position. By extraction of CVP catheter the TV gradients improved immediately. Malposition of CVP catheter or large CVP catheter could be considered as one of the rare causes of TV malfunction. Repositioning of CVP catheter brings dramatic improvement in this case.
Analysis Jakarta Stock Exchange Composite on the Indonesian Stock Exchange
Authors: Alexander Putri Sukma , Yuniningsih Yuniningsih
Published: August 2024

This study aims to determine the analysis of the influence from Dow Jones Industrial Average (DJIA), Inflation, Exchange Rates, Interest Rates against Jakarta Stock Exchange Composite (JKSE) on the Indonesian Stock Exchange (BEI). This research is quantitative study using secondary data taken​ from website with population that is overall movement Jakarta Stock Exchange Composite (JKSE) and taken sample with using the time series data method scale monthly for 72 months from January 2018 – December 2023. The instrument in this study analyzed using multiple linear regression analysis. The results of the study show that Dow Jones Industrial Average (DJIA), Inflation, and Interest Rates have influence one way to Jakarta Stock Exchange Composite (JKSE). While the Exchange Rates has an opposite influence to Jakarta Stock Exchange Composite (JKSE). This means that if happen improvement DJIA, Inflation, and Interest Rates then will followed with increase in JKSE, meanwhile if happen increase in Exchange Rate, there will be a decrease in JKSE.
Ethical and Legal Problems of the Monetary Evaluation of Germ Cells
Authors:   Senior Lecturer of the Department of Medical Law and Bioethics of the Samara State Medical University, Pechegina Yulia S.
Published: August 2024

The purpose of this article is to consider the question of the permissibility and effectiveness of the extension of the ownership regime to human germ cells. To achieve this goal, the paper considers the legal problems of the emergence of ownership of germ cells, the peculiarities of the exercise of the rights of ownership, use and disposal of human germ cells, evaluated the mechanisms of protection of ownership of germ cells from the point of view of applicability and reasonableness.
On the Need for Reconsideration and Transformation of Provisions of the Institution of Allegations on Falsification of Evidence in an Arbitration Procedure
Authors:   Associate Professor of the Department of Financial and Entrepreneurial Law of the Volgograd Institute of Management, Kantser Yury A.
Published: August 2024

The current arbitration procedural legislation is very dynamic. Digitalization and, in general, changes in the legislation of the Russian Federation, as a rule, are reflected in all the rules of the Arbitration Procedure Code of the Russian Federation. However, the institution of statements about the falsification of evidences in the arbitration process has not changed since the adoption of the Arbitration Procedure Code of the Russian Federation in 2002, in connection with which a number of problematic issues remain in the legal doctrine, in law enforcement arbitration practice and in the legislation, requiring rethinking and normative decision.
Gas exchanges, isotopic ratio of δ13C/12C and enzymatic activity in bell pepper under different irrigation
Authors: Ruiz Machuca Luz María , Broetto Fernando , Cruz de Souza Mara Lúcia , Dos Santos Coscolin Renata Bruna , Costa Vladimir Eliodoro , García Carrillo Mario , Concilco Alberto Ernesto
Published: August 2024

The cultivation of bell pepper demand irrigation practices to guarantee fruit production and quality. The objective of this work was to study the physiological and biochemical changes, as well as the variation in isotopic discrimination of δ13C in bell pepper plants submitted to different irrigation blades. The experimental design was organized in a completely randomized design (CRD) with three treatments (irrigation blades) and five replications. Blade 1 (B1): Ψm = 10 to 15 kPa, blade 2 (B2): Ψm = 34 to 40 kPa and blade 3 (B3): Ψm = 54 to 60 kPa. Four evaluations were performed at 50, 65, 80 and 95 days after transplantation (DAT), measuring Leaf water potential (Ψlw), net CO2 assimilation (A), stomatal conductance (gs), transpiration (E), isotopic discrimination (δ13C/12C), enzyme activity of nitrate reductase (NR), superoxide dismutase (SOD) and catalase (CAT). Finally, fruits were collected to determine productivity. Bell pepper plants with less water availability and, depending on their development, the leaf water potential was more negative, resulting in greater stomatal closure which caused a considerable decrease in the net CO2 assimilation, transpiration, enzyme activity of nitrate reductase and fruit production, and greater activity of antioxidative enzymes. The increase and duration of water restriction in bell pepper plants induced less isotopic discrimination of δ13C.