bluuebunny/crossref_metadata_2025 huggingface dataset:
Antinuclear antibodies appearing during PUVA therapy
Authors: Bruze M , Ljunggren B.
Published: August 2023

Antinuclear antibodies (ANA) were studied in patients receiving PUVA therapy. Ten patients out of 124, (8%), considered for PUVA had ANA prior to therapy. During PUVA treatment ANA appeared in 34 out of 100 patients. Eight patients with ANA initially were treated and in 4 of them a significant increase in ANA titre was noted. A statistically significant difference was noted, when the first and last ANA tests for each patient were compared. No such difference was seen in a control group consisting of 33 patients. All PUVA patients generating ANA were evaluated clinically and with a laboratory screening. This evaluation was negative in all patients except one who developed ANA of the nucleolar staining pattern together with symptoms consistent with a collagen vascular disease. The ANA titres were generally low and the staining pattern was of the homogeneous type in all patients but one.
IgA class reticulin antibodies in dermatitis herpetiformis: a good indicator of jejunal damage
Authors: Hällström O , Reunala T.
Published: August 2023

Fifty patients with dermatitis herpetiformis (DH) were examined. Reticulin antibodies (RA) were found in 34 (68%) patients; 25 (73%) of them had IgA class RA, seven (21%) had IgA and IgG class RA, and two (6%) had IgG class RA. A good correlation was found between the occurrence of RA and the presence of jejunal villous atrophy. Twenty-four (96%) of the patients with subtotal villous atrophy and nine (82%) with partial villous atrophy had RA as compared to only one (7%) of the 14 patients with normal jejunal mucosa. Gluten-free diet treatment caused disappearance of RA in every patient, suggesting that RA measurements can also be used in DH for monitoring adherence to the diet treatment.
Hairgrowth over the thenar and the sole in Mal de Meleda (Mljet disease)
Authors: Salamon T.
Published: August 2023

Two males suffering from Mal de Meleda are described. Both had hairgrowth over the right thenar and one of them had hairgrowth on the sides of the right index and middle finger. In a third male a few black hairs over the right sole were seen.
Gingival hyperplasia by nifedipine. Report of a case
Authors: Bencini PL , Crosti C , Sala F , Montagnino G , Tarantino A , Menni S , Piccinno R.
Published: August 2023

We describe a case of gingival hyperplasia in a 36-year-old renal transplantation recipient treated with nifedipine for severe arterial hypertension. The appearance of the gingival disorder was probably related to nifedipine intake. Histologically, in addition to the findings of acanthosis, papillomatosis and connective tissue hyperplasia, there was also an important plasma cell inflammatory infiltrate.
The effect of cyclophosphamide on the allergic contact reaction in guinea pig: dose effects and influence on peripheral blood
Authors: Anderson C , Groth O.
Published: August 2023

Single intraperitoneal injections of cyclophosphamide were administered 6 days before testing guinea pigs sensitized to oxazolone in order to study the effects on inflammatory cell populations in blood and dermis. Skin tests were assessed macroscopically (erythema and oedema) and microscopically (counting of the dermal inflammatory cell infiltrate). At the highest dose (300 mg/kg) the allergic contact reaction was augmented with increases in erythema and oedema and the mononuclear dermal infiltrate. At the lowest dose (75 mg/kg), redness and oedema and all components of the dermal inflammatory cell infiltrate decreased. Total and differential white blood counts up to 20 days after administration of cyclophosphamide showed that a dose-dependent leukopenia maximal around 6 days occurred. During the leukopenia the differential count showed a lymphocytosis with a marked granulocyte depletion. The augmentation of the contact allergic reaction produced at the highest dose of cyclophosphamide occurs despite a marked peripheral blood leukopenia. Cyclophosphamide´s effects at the lower dose would appear to be of a non-specific anti-inflammatory nature.
Serologic studies of erythema chronicum migrans Afzelius and acrodermatitis chronica atrophicans with indirect immunofluorescence and enzyme-linked immunosorbent assays
Authors: Asbrink E , Hovmark A , Hederstedt B.
Published: August 2023

To determine whether antibodies to Borrelia spirochetes were present, sera from 88 patients with uncomplicated erythema chronicum migrans Afzelius (ECMA), from 9 patients with ECMA-related extracutaneous complications and from 26 patients with acrodermatitis chronica atrophicans (ACA) were submitted to an enzyme-linked immunosorbent assay (ELISA) and an indirect immunofluorescence (IF) assay. The assays were calculated to be 95% specific. There was good correlation between the IF test with a polyvalent conjugate and IgG ELISA. Of patients with uncomplicated ECMA, 18% were seropositive by IgG ELISA and 11% by IgM ELISA, and 15% showed elevated IF titers. Elevated serum antibody levels of IgG as measured by ELISA and elevated IF titers were found in all patients with extracutaneous complications and in the patients with ACA. Declining IgG titers were observed at follow-up 6-12 months after therapy, but the majority of the patients with ACA were still seropositive.
Hematologic disease in scleroderma syndromes
Authors: Doyle JA , Connolly SM , Hoagland HC.
Published: August 2023

Review of 4 430 patients with a diagnosis of scleroderma, morphea, or eosinophilic fasciitis has revealed 16 patients with one of a variety of serious hematologic diseases. Although it is not possible to comment on the exact relationship between the dermatologic disease and the hematologic disorder, in seven patients there appeared to be a close temporal relationship between the onset of the two conditions. The development of a serious hematologic disease, especially a lymphoproliferative process, may rarely be seen not only in patients with eosinophilic fasciitis but also in those with systemic or localized scleroderma.
Hyperkeratosis lenticularis perstans: report on three cases
Authors: Rosdahl I , Rosén K.
Published: August 2023

Three women with hyperkeratosis lenticularis perstans (HLP) are described. The lesions developed after the age of 45 and there was no family history of this disease. The possible role of UV-light in the pathogenesis of this disease is discussed.
AIDS-induced decline of the incidence of syphilis in Denmark
Authors: Poulsen A , Ullman S.
Published: August 2023

The incidence rate of acquired syphilis per 100 000 total population in Denmark increased by 70% from 6.8 in 1978 to 11.6 in 1982. In 1984 this incidence had decreased by 61.2% to 4.5. The fluctuation of the number of acquired syphilis predominated in the male population with an increase of 71.8% during the five year period 1978-1982 and a decrease of 63.2% during the years 1983 and 1984. In 1978, the incidence of acquired syphilis in males was 11.3 per 100 000 total population increasing to 19.5 in 1982, decreasing to 7.2 in 1984. The decreasing number of acquired syphilis cases during the past two years are correlated to a lower number of sexual contacts among homosexual men because of fear of AIDS.
Oral acyclovir suppression of recurrent genital herpes: a double-blind, placebo-controlled, crossover study
Authors: Halsos AM , Salo OP , Lassus A , Tjøtta EA , Hovi T , Gabrielsen BO , Fiddian AP.
Published: August 2023

A randomised, double-blind, placebo-controlled, crossover study was conducted in 31 male patients with a history of frequently recurrent genital herpes who received consecutively 200 mg acyclovir and matching placebo by mouth four times a day for 12 weeks each. During acyclovir therapy recurrences were completely prevented in 24 (77%) and were reduced in both frequency and duration in the remainder compared with those occurring during treatment with placebo. The incidence and nature of adverse events reported during each treatment period was virtually identical. No long-term effects on recurrence rates were discernible but chronic suppressive therapy can be considered to offer the means of controlling the severe forms of disease experienced by some patients.
Abstracts from 12th Georg Rajka International Symposium on Atopic Dermatitis
Authors: Listed No authors
Published: August 2023

Abstract is missing (Abstract Book)
Clinical Characteristics of Children in This New Global Immunodeficiency
Authors: WL Huang
Published: August 2023

After the implementation of the modernization of telecommunication, there were alterations in the part of the energy of the internal five massive organs (Liver, Heart, Spleen, Lungs and Kidney) that composes the human body. This is the most important part responsible to protect and prevent the formation of the majority of diseases nowadays. When the energy of the body is weak, it leads to our immune system to not work properly, causing an increase chance to have any psychological or clinical manifestations of any kind of diseases. In this article, I will show the different clinical manifestations that children can have when presenting energy deficiency situation and this is the focus of this article, to identify these patients to treat them accordingly. The medications of choice to be used in this new type of children nowadays are highly diluted medications such as homeopathy created by Hahnemann (1755-1843). It is also important to use the theory created by myself (2020) titled Constitutional Homeopathy of the five Elements Based on Traditional Chinese Medicine to replenish the energy of these organs.
Co-occurrence of Rheumatoid Arthritis and Pulmonary Tuberculosis: A Diagnostic and Therapeutic Challenge
Authors: L Devi
Published: August 2023

The co-occurrence of rheumatoid arthritis (RA) and pulmonary tuberculosis (TB) poses diagnostic and therapeutic challenges in patients receiving immunosuppressive therapy. In this case report, we present a 45-year-old male with a history of multiple joint pain for 8 years, suggestive of RA. The patient had been taking NSAIDs for 3 years, but his symptoms worsened in the last month. Laboratory investigations revealed elevated levels of rheumatoid factor (RF) and anti-cyclic citrullinated peptide (antiCCP) antibodies, supporting the diagnosis of RA. He was initiated on methotrexate, hydroxychloroquine, and folate. However, he developed respiratory symptoms, including a productive cough and fever. Physical examination findings indicated respiratory abnormalities and radiographic imaging showed bilateral opacities. Further assessment with HRCT thorax revealed fibrocavitary lung lesions and mediastinal lymphadenopathy. Microbiological confirmation through CBNAAT testing demonstrated the presence of Mycobacterium tuberculosis, leading to the diagnosis of pulmonary Tuberculosis. The patient was promptly started on anti-tubercular treatment. This case highlights the challenges faced in managing patients with both RA and TB under immunosuppressive therapy. A multidisciplinary approach involving rheumatologists and infectious disease specialists is crucial for optimal management and favourable outcomes.
Radiation Protection Issues in Clinical Research Involving X-Ray Diagnostic Radiology Procedures
Authors: Fatukasi Joseph
Published: August 2023

Aim: To review radiation protection issues in clinical diagnostic studies that involves the use of x-rays. The Issue: X-rays imparting low dose have some dominance in the use of ionising radiation (IR) in clinical radiological investigations. In good clinical diagnostic practice, with radiation effects anticipated to be wholly stochastic, it is simply not possible to be specific about risks to health other than to acknowledge an anticipated increase in probability with dose. Difficulties in making an assessment of risk can be further compounded given possible cumulative effects from previous exposures and from varying clinical state. Scientific Considerations: Clinically focused research involving IR and subjects (reviewed by ethics committees and other parties) necessarily involves assessment of the study protocol. In addition to the embodiment of radiation protection principles, the protocol must conform to the general ethical principles of beneficence, prudence, justice and dignity, all of which are important. The protection aspects arising from the use of radiation needs to be assessed by radiation experts, the safety of study participants needing to be weighed against the necessity for the study. This information must be fully explained to the participant as part of the process of seeking consent. In obtaining consent, the participant information sheet must be of an appropriate quality of language and possible specific risks provided in a transparent manner. Conclusion: In clinical studies that involve the use of IR, the study protocol must contain all relevant radiation protection measures. It is important that review of the protocol should involve IR experts.
Unraveling the Genetic Complexity: A Case Report of MYLK Gene Mutation in a Patient with SCAD
Authors: Abozeed Mostafa
Published: August 2023

Spontaneous Coronary Artery Dissection (SCAD) is a rare and potentially fatal disorder characterized by a tear in the wall of a coronary artery, leading to reduced blood flow to the heart. Although its exact cause remains elusive, SCAD is often associated with fibromuscular dysplasia and other connective tissue disorders. Here, we present a case of a 34-year-old African-American male with SCAD, hypertension, and obesity, whose family history included myocardial infarction, hypertension, and diabetes mellitus. Extensive imaging and cardiovascular evaluation revealed severe stenosis in the left anterior descending artery and a dissection flap in the left main coronary artery. Further genetic testing identified a variant of uncertain significance (VUS) in the MYLK gene, which has been linked to aortic dissections. While MYLK gene mutations have been reported in some SCAD and thoracic aortic aneurysm and dissection (TAAD) patients, they appear to be relatively rare. This case underscores the potential genetic basis of SCAD and highlights the importance of continued research to understand the role of MYLK gene mutations in SCAD and TAAD pathogenesis. Further investigation is warranted to determine the significance of the VUS identified in this patient
Transportation-Related Human Factors in High-Altitude Regions: Review, Needs, and Novelties
Authors: SM Easa
Published: August 2023

The low pressure at high altitudes (above 2500 m) causes hypoxia (decreased oxygen) that affects people’s physiological and psychological characteristics. Specifically, hypoxia may affect the neural function of the brain, leading to severe cognitive deficits and a significant decline in memory function and attention. This article addresses the effect of human factors on transportation design and operation at high altitudes (HA), with some details on the Tibet-China region. Specifically, the paper first reviews the basic transportation-related concepts for high altitude, including oxygen and temperature levels, driver perception-reaction time, hazard perception, vehicle speed, and walking speed. Then, the transportation users affected by high altitudes are discussed, including drivers, pedestrians, cyclists, passengers, and others. Next, the impacts of human factors on highway design and operation for HA regions are discussed along with the research needs. Finally, recent innovations to address the challenges of HA transportation are presented, along with case studies comparing some human factors of the plateau and plain areas. This article represents a valuable reference for future research in HA regions to improve transportation design and safety
Factors Influencing Biomechanics during Pregnancy and Ergonomic Modifications to Alleviate Discomfort: A Descriptive Review
Authors: G Akshita
Published: August 2023

This in-depth analysis covers the biomechanical changes that take place during pregnancy and the effectiveness of ergonomic therapies for reducing pain and enhancing maternal wellbeing. Significant physiological changes brought on by pregnancy affect many aspects of the body, including biomechanics. During pregnancy, the lower back and lumbopelvic region are particularly prone to pain and musculoskeletal problems. A variety of factors, including weight growth, hormone changes, ligament elasticity, and postural changes, affect how the body moves and put more strain on the musculoskeletal system. Pregnant workers' biomechanical stress at work is made worse by occupational factors like physical demands and poor ergonomics. Various ergonomic solutions have been recommended during pregnancy to reduce discomfort and improve biomechanics. These include auxiliary devices (such as pregnancy belts, support bands), activity adaptations, psychosocial support, workplace modifications (such as adjustable workstations, supportive seats), and education and communication to empower women with knowledge of ideal body mechanics. The use of these therapies throughout pregnancy can increase comfort, preserve musculoskeletal health, and promote general wellbeing. This study emphasises the numerous effects on pregnancy biomechanics and stresses the value of integrating and synthesising already available information. Healthcare professionals, companies, and individuals can significantly reduce discomfort and promote a healthier and more comfortable pregnant experience by implementing evidence-based ergonomic changes.
North Sulawesi Single Local Fruit Detection Using Efficient Attention Module Based on Deep Learning Architecture
Authors: Vecky C. Poekoel  , Putro Dwisnanto , Jane Litouw  , Rivaldo Karel  , Pinrolinvic D. K. Manembu  , Abdul Haris Junus Ontowirjo  , Feisy D. Kambey  , Reynold F. Robot
Published: August 2023

A Local fruit detection system is an agricultural vision field that can be implemented to increase the profit of a commodity. Besides that, North Sulawesi has a variety of local fruits which are widely used by people in their area and have a high selling value. The sorting system is an essential process of agricultural robots to sequentially separate fruit one by one. This automation process requires an accurate vision system to detect and separate fruit precisely and precisely. In addition, the implementation of a practical application demands a method to be able to work in real-time on low-cost devices. This work aims to design a local single fruit detection system for Sulawesi North by applying deep learning architecture to produce high performance. The architecture is designed to consist of an effective backbone for rapidly separating the distinctive features, an efficient attention module to improve feature extraction performance, and a classifier module employed to estimate the probabilities of each local fruit category. As a result, the designed model produces an accuracy value of 99,27% and 99,57% on the Fruits-360 and the local datasets, respectively. It outperforms other light architectures. In addition, deep learning models are designed to produce higher efficiency values than other competitors and can operate quickly at 100,488 Frames per Second.
Modification of Non-local Mean Algorithm Using Parallel Calculation for Image Noise Reduction
Authors: Al Farissi  , Wondo Wondo
Published: August 2023

Noise in digital image processing is a noise that occurs at pixel values due to random colour intensity. Several types of noise models include Gaussian noise, speckle noise, impulse noise, and Poisson noise. Before processing image data, a noise reduction process is required. One of the noise reduction algorithms used for gaussian noise models is Non-local Mean. This algorithm performs calculations sequentially on each pixel in the search block. Due to a large number of pixels and search block area in the image, the noise reduction process using the Non-local Mean algorithm is very slow. This study proposes the concept of parallel calculations for the Non-local Mean algorithm. This concept divides the search block into three parts and performs calculations on each part simultaneously. The experimental results show that the Non-local Mean algorithm with parallel calculations can reduce noise up to 30% faster if the noise standard deviation is above 30.
Hole Detection in Plastic Mulch Using Template Matching and Machine Learning Algorithms
Authors: Aziz Abdul , Arkeman Yandra , Kusuma Wisnu Ananta , Kurniawan Farohaji
Published: August 2023

Mulch is a ground cover material to maintain soil moisture and temperature stability as a plant medium. Mulch also helps prevent weed growth for better plant growth. For planting with plastic mulch, farmers need to make holes in the mulch the day before planting. Precision agriculture is needed because it can obtain savings in input financing, labor, and better yields, so this research aims to identify holes in mulch based on Unmanned Aerial Vehicle images. The advantage of this research is that it can monitor each plant based on the mulch holes, and the number of holes identified can be used as a parameter to estimate the amount of crop production. This research combines Template Matching Algorithm and Machine Learning Algorithm to improve accuracy in predicting holes in mulch. Three machine learning algorithms are used, namely the Random Forest, Support Vector Machine, and XGBoost. The data used is an orthophoto mosaic from aerial photographs. Nine areas were taken from orthophotos to be used as research samples. The results of this study obtained the highest average recall, precision, and f-measure values using the Support Vector Machine algorithm with a recall value of 87.7%, precision of 97.5%, and f-score of 92.3%. This research focuses on reducing detected commission errors. Therefore, omission errors were still detected in the damaged or leaf-covered holes.
Similar Questions Identification on Indonesian Language Subject Using Machine Learning
Authors: Hasmawati  , Ade Romadhony
Published: August 2023

Question similarity is carried out to evaluate similarities between questions in a collection of questions in the question and answer forum and on other platforms. This is done to improve the performance of the question-and-answer forum so that new questions submitted by users can be identified as similar to existing questions in the database. Currently, research related to question similarity is still being carried out on foreign language datasets. The purpose of this research is to identify the similarity of questions in a collection of questions in Indonesian. The method used is Support Vector Machine and IndoBERT. For feature extraction, we evaluate the lexical features and syntax features of each question. For lexical feature extraction, we use the cosine similarity algorithm to calculate the distance between two objects which are represented as vectors. For syntax feature extraction we use the Indonesian part of speech tagger (POS Tag). The dataset used is a collection of questions on Indonesian subjects at the primary and secondary school levels. The results of this study show that the best performance of the Support Vector Machine is obtained from the use of the cosine similarity feature with an accuracy of 85%. While the use of the POS Tag feature or the combination of POS Tag and cosine similarity causes the model to be overfitted and the accuracy decreases to 77%. Meanwhile, for the IndoBERT model, an accuracy of 95% was obtained.
Emprendimiento, innovación y gamificación en la Educación Media Técnico Profesional (EMTP)
Authors: Vera-Sagredo Angélica , Constenla-Núñez Jaime , Jara-Coatt Pilar
Published: August 2023

En los últimos años, en Chile se ha observado un incremento en la Educación Media Técnico Profesional. No obstante, este aumento no ha significado necesariamente mejoras en los aprendizajes de los estudiantes; por eso, la importancia de potenciar este tipo de educación radica en la necesidad de apoyar la competitividad y la posibilidad de empleo de las personas para favorecer la movilidad social de quienes no continúan carreras universitarias. En este contexto, desarrollar competencias de innovación y emprendimiento a través de metodologías activas como la gamificación podría fortalecer los aprendizajes del alumnado. Esta investigación, por tanto, tuvo como objetivo determinar la percepción de los estudiantes sobre innovación, emprendimiento y gamificación en Educación Media Técnico Profesional (EMTP). El estudio corresponde a un diseño no experimental, transversal con un enfoque cuantitativo de alcance descriptivo-correlacional. Participaron en la investigación 724 estudiantes de seis establecimientos de la región del Biobío, Chile. Para la recolección de datos se empleó una encuesta tipo escala Likert de percepción sobre emprendimiento, innovación y gamificación en educación (AEIGE) versión estudiante. Con la finalidad de cumplir con los objetivos del estudio se examinaron diferencias de medias a través de la prueba t de Student y Anova, y las posibles relaciones a través de la prueba estadística coeficiente de Pearson. Los principales resultados muestran que los estudiantes otorgan valoraciones positivas a aspectos relacionados con el uso del juego en el proceso de enseñanza y aprendizaje, así como algunas características de los profesores innovadores, como el humor y la empatía. Además, se evidencia que el alumnado presenta un rol poco activo en el desarrollo de las clases. Se concluye que las mujeres darían mayor relevancia a las competencias de emprendimiento y al uso del juego como estrategia de enseñanza aprendizaje, y que existiría una relación significativa entre innovación y emprendimiento, y entre emprendimiento y gamificación.
Identifikasi Struktur Kerak Di Bawah Permukaan Jawa Timur Berdasarkan Hasil Tomografi Seismik Menggunakan Model Kecepatan Gelombang P Dan Gelombang S
Authors: Ulfa Uli , Fitrianingtyas Rahmawati , Noradika Maharani Yohana , Wibowo Adhi
Published: August 2023

Tectonic conditions that are vulnerable to earthquakes have become a trigger for researchers to conduct studies on subsurface conditions in East Java. A seismic tomographic study based on the P-wave and S-wave velocity models was applied to identify crustal structures in East Java. The research data totaled 3,893 earthquake events and 28 stations from the Meteorology, Climatology and Geophysics Agency (BMKG) in the 2009-2017 period covering coordinates 5oSL- 11oSL and 110o - 115o EL. The modeling results in this study are expressed in velocity perturbations against the ak135 one-dimensional reference velocity between -5% to 5%. The results of this study indicate that in the central of East Java, there is a negative velocity anomaly which is identified as a sedimentary layer that fills the basin in the Kendeng Zone and volcaniclastic deposits in the Southern Mountains Zone to a depth of 5 km. The dominant negative velocity anomaly in southern East Java is associated with the presence of intrusive and bedrock in the Southern Mountain Zone. The transition zone between the crust and upper mantle in East Java is observed at a depth of 35 km below the surface.
Pemodelan Numerik Hubungan Pola Curah Hujan Wilayah Equatorial di Pulau Sumatera Terhadap Fenomena ENSO dan IOD
Authors: Ariska Melly , Darmawan Adam , Akhsan Hamdi , Supari Supari , Irfan Muhammad , Iskandar Iskhaq
Published: August 2023

A numerical modeling has been built for the relationship between rainfall in the equatorial region of Sumatra to the ENSO and IOD phenomena by taking data from 1991 to 2020 at three stations located in the western region of Sumatra Island, namely SM Japura, SM Minangkabau and SM Hang Nadim. The method used in this study is the method of correlation and linear regression on the Niño3.4 Index variable and the Dipole Mode Index on the amount of rainfall. The data visualization process is carried out with the output in the form of plots and graphs with Goole Colab coding. The resulting graph is a graph of the ENSO and IOD phenomena, as well as a regression graph between The Niño3.4, DMI and the amount of rainfall per month. This study was conducted with the aim of knowing how much influence the El Niño Southern Oscillation (ENSO) variable represented by the Niño3.4 Index and the Indian Ocean Dipole (IOD) represented by DMI had on rainfall in the equatorial region in the 1991 – 2020 period and to see the trend of significance between the two towards the equatorial region on the island of Sumatra. Rainfall in Indonesia's equatorial region tends to be influenced by IOD compared to ENSO. The combination of the two at the same time can cause a significant change in the amount of rainfall. La-Niña and negative IOD occurred in 1992, 1996, 1999, 2000, 2005, 2008, 2011 and 2016. The average rainy day index (SDII) tended to decrease in Japura Island in 1996, 2005, 2011, 2016 , at SM Minangkabau in 1992, 1996, 1999, 2000, 2016 and at SM Hang Nadim in 1996, 1999 and 2008. Meanwhile the longest series of wet days tended to decrease in SM Japura in 1992, 1996, 1999, 2005, in SM Minangkabau in 1992, 1996, 2005, 2008, and in SM Hang Nadim in 1992, 2000, 2005, 2008 and 2011. The longest series of dry days tended to increase in SM Japura in 1996, 2011, in SM Minangkabau in 1996, 2000, 2011, and at SM Hang Nadim in 1996.
TOWARDS THE BEST MODEL GOOD CORPORATE GOVERNANCE AND KNOWLEDGE MANAGEMENT TO IMPROVE PERFORMANCE THROUGH JOB SATISFACTION
Authors: Karyatun Subur , Yuliantini Tine , Saratian Eko , Paijan Paijan , Soelton Mochamad , Riadi Elvira
Published: August 2023

The purpose of this study was to examine and assess the impact of Good Corporate Governance and Knowledge Management on Organizational Citizenship Behavior through the mediation of Job Satisfaction. Quantitative research using questionnaire collection techniques and SEM Smart-PLS, with a saturated sample of 86 employees. Finding, Good Corporate Governance has no effect on Organizational Citizenship Behavior, Knowledge Management has a significant effect on Organizational Citizenship Behavior, Good Corporate Governance and Knowledge Management has a significant effect on Job Satisfaction. Job satisfaction does not mediate the effect of good corporate governance on Organizational Citizenship Behavior, but is able to mediate the relationship between Knowledge Management and Organizational Citizenship Behavior. Interestingly, good company GCG does not necessarily increase employee OCB. GCG which still seems to be carried out only by decision makers in a directed manner so that employees do not feel they are part of the GCG implementation in the company.
Assessment of Changes of Safe Distances in Case of Violations of the Gas Pipeline Testing Regulations
Authors:   Gazprom VNIIGAZ LLC, Gamera Yu.V. , Petrova Yu.Yu. ,   Gazprom VNIIGAZ LLC, Volynets I.G. ,   Gazprom VNIIGAZ LLC, Dokutovich A.B. ,   Gazprom VNIIGAZ LLC
Published: August 2023

Accidents occurring during the process of gas pipelines testing are characterized by the impossibility of the occurrence of thermal radiation of jet flames and fire in the pit-damaging factors dominating the operation stage of the facility. In addition, what is happening cannot be accompanied by the baric effect of chemical explosions. However, taking into account the significant increase in pressure in the gas pipeline during pneumatic tests, such damaging factors of the accident as the scattering of fragments, the pressure effect of a high-speed jet and the baric effect of the primary shock wave are amplified. The issue of ensuring the safety of personnel present near the test site becomes relevant. As a result, the need occurs to determine precisely the safe distances to the gas pipeline. Protective zones for the population are also established based on the identified safe distances. Within the framework of the risk-oriented approach, the procedure for determining safe distances is reduced to calculating the distances at which damaging factors lose their damaging properties. When assigning protective zones, it is required to consider the possibility of changing the indicator under consideration, due to probable errors of personnel in the preparation and conduct of tests. Even non-critical miscalculations can significantly affect the determination of a safe distance. The article presents an assessment of the relative values of safe distances, taking into account possible violations of the regulations regarding backfilling and filling with water or air, during hydraulic or pneumatic tests of gas pipelines. Relative values of safe distances are also established in terms of the scattering of fragments and the impact of an air shock wave of a physical explosion on people and building objects.
Minimization of the Danger of Metallized Mine Drains
Authors:   SRSPU (NPI), Golik V.I. ,   Moscow Politechnic University, Razorenov Yu.I. ,   SRSPU (NPI), Belodedov A.A. ,   SRSPU(NPI), Versilov S.O. ,   SRSPU (NPI)
Published: August 2023

Increase in ore production volumes and the use of large-sized equipment contribute to the loss of ores during mining, which gives rise to the phenomenon of natural leaching. On the example of deposits of the Sadon ore cluster, the hazard of metallized mine effluents for living matter and humans is shown. Of the relatively young methods of mine water purification, the most promising is the combination of electrochemical softening of mine effluents with electrodialysis desalination and concentration. The improvement of environmental protection technologies is developing on the basis of the managed disposal of mining and processing waste as a generator of natural leaching. The results are presented related to the experimental study of the parameters of metals extraction from the mine effluents by electrodialysis desalination with simultaneous concentration. The mechanism is formulated related to the development of oxidative processes of sulfide minerals in the presence of carbon dioxide of the mine atmosphere with the occurrence of electrochemical bonds between the crystals and mineral grains. The process of electromembrane treatment of metal-containing wastes is detailed. It is shown that during the electrochemical decomposition of salt systems, associated commercial products are formed. The dynamics of pollution of the Ardon river washing the Sadon deposit is given. The chemical processes of leaching of lost ores are described. An installation for electrochemical wastewater treatment is recommended, and a quantitative assessment of its efficiency is given. It is noted that the processes of electrochemical wastewater treatment are adequate, described by linear graphs and subject to correction. It is shown that the drains of mines are hazardous for living matter. It is indicated that the improvement of environmental protection technologies will be developed in the direction of waste disposal of mining and processing. The general principle of mine water hazard reduction is a combination of electrochemical softening with electrodialysis desalination and concentration.
Subsea Wells Blowout Occurrence and Methods of Source Control
Authors:   Gubkin Russian State University of Oil and Gas (National Research University), Dzyublo A.D. ,   Oil and Gas Research Institute Russian Academy of Sciences, Perekrestov V.E. ,   Gubkin Russian State University of Oil and Gas (National Research University), Belozerov A.A. ,   Gazprom Dobycha Shelf Yuzhno-Sakhalinsk LLC
Published: August 2023

The article will be useful to the scientists and specialists in the oil and gas industry involved in the construction of offshore wells and the blowout response. The article provides a brief list of the implemented oil and gas projects on the shelf of the Russian Federation. The principle of two barriers, which must be observed throughout the entire life cycle of the well, is considered. The main reasons for the transition of kick into blowout are considered, and the most well-known cases of blowout of the offshore wells in the industry are given. According to the SINTEF Offshore Blowout database, the worldwide statistics of loss of well control from 2000 to 2015 are given. The reasons for the development of offshore fields with large-diameter wells are described, and the risk of increased complexity in controlling such wells in the event of blowout is noted. The peculiarities of subsea wells blowout are described. As is known, the blowout of a gas well is associated with the creation of a gas-water plume, which makes it difficult or completely deprives vertical access to the wellhead in shallow water during emergency rescue operations. The paper shows a model of gas-water plume in shallow water conditions, and describes the processes occurring when the gas plume floats up and its impact on ships (drilling rigs, supply vessels and etc.). An example is given related to the modeling a rising gas-water plume using computational fluid dynamics (CFD) at various sea depths and flow rates of a blowing well. The methods of well source control are considered, the current schemes for installing an capping stack at the wellhead of a subsea blowing well are described. The advantages and limitations of each well source control method are presented.
Substantiation of programs for hygienic training on prevention of disorders of the musculoskeletal system and the eye and adnexa
Authors: Khorosheva IV
Published: August 2023

The impact of modern factors of educational environment and extracurricular factors results in the risk of the development and progression of functional impairment and chronic diseases of the musculoskeletal system, as well as the diseases of the eye and adnexa in students. The study was aimed to substantiate the programs of hygienic education in terms of compliance with hygienic recommendations on prevention of the diseases of the musculoskeletal system and the eye and adnexa based on the analysis of scientific papers. The review of studies conducted in 2011–2023 by the Russian and foreign experts that were focused on the impact of the educational environmental factors and the daily routine components on the students’ health status was performed using the E-Library, PubMed, Web of Science electronic databases. The impact of such risk factors, as irrational daily routine organization, on the health of students attending general schools, professional and higher educational institutions has been shown. The risk of disorders of the musculoskeletal system and the eye and adnexa resulting from the excess stay in digital environment, lack of physical activity, irrational leisure time organization has been assessed. It is necessary to develop the hygienic training programs involving teachers, lecturers and parents to prevent the effects of the risk factors for disorders of the mysculoskeletal system and the eye and adnexa.
Physical and Mechanical Properties of an Artificial Aggregate Made up of Ground Granulated Blast-Furnace Slag
Authors: Ibrahim Mais A. , Atmaca Nihat , Atmaca Adem
Published: August 2023

Manufacturing artificial aggregate by utilizing waste materials has gained great importance as the aggregate occupies a high volume in concrete (60–70%). In this paper, ground granulated blast furnace slag (GGBFS) is utilized in aggregate manufacturing. Cold bonding and sintering methods were used as production processes. The pellets were put through a series of tests like dry density, specific gravity, water absorption, and crushing strength. The results indicated that the density of pellets increased by increasing the GGBFS dosage while the water absorption capacity was reduced. Furthermore, the highest crushed strength was recorded at 50% addition of GGBFS.
Types of financial aid delivered during COVID-19 pandemic: A systematic literature review
Authors: Mustaffa Abd Hadi , Ahmad Noryati
Published: August 2023

COVID-19 pandemic has become worsen day by day. Almost 200 countries' economies were affected, and it shows that global GDP declined by 6.7% in the year 2020. In detail, the community and businesses were affected by losing jobs and lost revenue. Hence, most countries face challenges by forcing them to deliver and channel financial aids to recover and stabilise their economy. The study's main objective is to systematically review the financial aids of countries during the COVID-19 pandemic in a global context. The review was guided by Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). As a result, 20 articles were selected and systematically reviewed. The results via thematic analysis identified six themes, 1) government economic booster, 2) employee stimulus package, 3) financial assistance to business, 4) community financial assistance, 5) tax or debt relief, and 6) health and emergency aid. The six themes were further discussed regarding how financial aids work, which party is handling more financial aids, a few related issues, and recommendations to improve financial aid in the future crisis. In addition, this study provides two significant contributions in the later section.
Socioeconomic, environmental, and health impacts of reusing treated wastewater in agriculture in some Arab countries, including occupied Palestine, in view of climate change
Authors: Salem Hilmi S.
Published: August 2023

The increase in water stress and shortage, facing many countries around the world, is one of the main difficulties confronting practical progress and sustainable development and management. Accordingly, managing the water assets of many countries around the world is nowadays a big challenge due to immense difficulties and vulnerabilities, including rapid industrialization and urbanization processes, population growth, geopolitical instability, and the effects of environmental changes, namely global warming and climate change. Because of global fresh waters scarcity and shortage, the demand for using non-conventional water resources, such as reusing treated wastewater for irrigation and industrial purposes, has become a nessitiy. However, the reuse of effluents for agricultural irrigation can have negative impacts on crop quality and soil conditions, as well as on public health and the environment. Moreover, improper management of agricultural irrigation with treated wastewater can also cause problems for plant production and soils’ physical and chemical propeties. This paper investigates the status of freshwater and wastewater in view of climate change, and socioeconomic, environmental, and health impacts of reusing treated wastewater for irrigation in the Arab region, with the focus on the Occupied Palestinian Territories (OPT), as an example. The paper concludes that: 1) Approximately 13.2 billion cubic meters (BCM) of wastewater is yearly produced in the Arab countries, of which 5.7 BCM (43.2%) is treated and 7.5 MCM (56.8%) is untreated and dumped in open environments; 2) Regarding the OPT, where more than 87% of its fresh water resources are controlled and forcefully taken by the Israeli occupation authorities, Palestinians discharge large amounts of untreated wastewater into open lands (as in the case of the occupied West Bank) and in the Mediterranean Sea (as in the case of occupied and besieged Gaza Strip); and 3) The reused portion of treated wastewater in the OPT is close to zero.
Effect of sodium-glucose cotransporter 2 inhibitors on left atrial remodeling and prognosis in patients with type 2 diabetes and heart failure with reduced ejection fraction
Authors: Yu Songqi , Sun Yuxi , Wang Ning , Lv Xin , Si Jinping , Zhang Xinxin , Zhang Yanli , Liu Ying
Published: August 2023

Aims

Sodium-glucose cotransporter 2 inhibitors (SGLT2is) have been found to minimize hospitalization for heart failure and cardiovascular death. Cardiac reverse remodeling may be a mechanism responsible for the favorable clinical efficacy of SGLT2is on heart failure. To date, few studies have examined their effects on the left atrium. Therefore, the purpose of this study was to explore whether SGLT2is improve left atrial adverse remodeling in patients with type 2 diabetes and heart failure with reduced ejection fraction (HFrEF).

Methods

A single-center, retrospective, observational study was conducted. Consecutive patients with type 2 diabetes and HFrEF hospitalized at the First Affiliated Hospital of Dalian Medical University for acute decompensated heart failure between 1 January 2019 and 1 March 2022 were identified. On the basis of their treatment strategies, the enrolled participants were classified into SGLT2i and non-SGLT2i groups. The primary end point was all-cause mortality. Changes in left atrial echocardiographic indices from baseline to follow-up were also assessed.

Results

A total of 198 patients (mean age: 63.96 ± 12.11 years, 20.71% women) were included. Greater reductions from baseline were seen with SGLT2i in the left atrial diameter (P < 0.001), left atrial superior–inferior diameter (P = 0.027), left atrial transverse diameter (P = 0.020), left atrial volume (P = 0.005), and left atrial volume index (P = 0.004). Moreover, 48 cases (48.48%) in the SGLT2i group and 33 (33.33%) in the non-SGLT2i group showed left atrial reverse remodeling (P = 0.003). Survival analysis demonstrated significantly lower overall mortality in the SGLT2i group compared with the non-SGLT2i group.

Conclusion

This study found that SGLT2i therapy promoted left atrial structure reverse remodeling. This beneficial effect may be a vital mechanism by which SGLT2i improved clinical outcomes in patients with HFrEF.
Prognostic impact of red blood cell distribution width in chronic heart failure patients with left ventricular dysfunction
Authors: Ferreira Ana Isabel , Silva João Enes , Melo Nuno , Oliveira Diana , Silva Clara , Lume Maria , Pereira Joana , Almeida Jorge , Araújo José Paulo , Lourenço Patrícia
Published: August 2023

Aims

Red blood cell (RBC) distribution width (RDW) measures RBC variations in size. Higher RDW values have been associated with poor outcome in acute heart failure (HF). We aimed to assess the prognostic impact of the RDW in chronic HF.

Methods

We retrospectively analysed a cohort of chronic HF patients with left ventricular systolic dysfunction followed in our HF clinic between January 2012 and May 2018. Patients with missing data concerning RDW were excluded. Patients were categorized according to RDW tertiles: ≤13.5%; between 13.5 and 14.7%; and >14.7%. Patients were followed until January 2021; all-cause mortality was the end point analysed. The association of RDW with all-cause mortality was assessed with a Cox-regression analysis. Two multivariate models were built.

Results

We studied 860 chronic HF patients, 66.4% males, mean age 70 (standard deviation, SD 13) years. Patients were followed for a median of 49 (29–82) months. During this period, 423 (49.2%) patients died. Mortality increased with increasing RDW tertiles. Patients with RDW >14.7% had a HR of mortality of 1.95 (1.47–2.58), p < 0.001 (model 1) and of 1.81 (1.35–2.41), p < 0.001 (model 2) when compared with those with RDW ≤13.5. Patients in the second RDW tertile had an all-cause death HR of 1.47 (1.12–1.93) and of 1.44 (1.09–1.90) in models 1 and 2, respectively.

Conclusions

Chronic HF patients with RDW values >14.7% presented an almost 2-fold higher risk of dying in the long term than those with RDW <13.5%. RDW is a widely available and easily measured parameter that can help clinicians in the risk stratification of chronic HF patients.