bluuebunny/crossref_metadata_2025 huggingface dataset:
الدراسة النحوية عن الاشتغال وأساليبه فى القرآن جزء عمّ
Authors: Abrar Muh. , Asriani Asriani , Hamid Abdul
Published: March 2024

This research shows the definition of the worker's work from the work and its provisions, and it shows the surahs that contain the worker's work from the work in the thirtieth part of the Qur'an. As for the research methods that the researcher uses to study this writing, it is the qualitative research approach, in terms of its type. From this research, the researcher knew that the worker's occupation of the work is a preceding object, even if two sentences are nominative and accusative. The nominative is like the subject and the accusative is like the object. Also, the researcher knew that six surahs that contain the preoccupation of a worker from the work in the thirtieth part of the Qur’an, namely, Surat Al-Duha, Surat Al-Shams, Surat Al-Fajr, Surat Al-Naza’at, Surat ‘Abs, and Surat Al-Naba’. The researcher found that the worker is busy with what is done in the thirtieth part of the Qur’an. There are ten verses that contain work, which are two verses in Surat Al-Duha, verse: 9 and 10, three verses in Surat Al-Shams, verses: 5,6, and 7, one verse in Surat Al-Fajr, verse: 15, one of the verses in Surat Abas, verse: 20, two verses in Surat Al-Naza'at, verses: 30 and 32, and the other from the verse of Surat Al-Naba, verse: 29.
Hubungan Laju Endap Darah (LED) dengan Kejadian Syok pada Pasien Multisystem Inflammatory Syndrome in Children (MIS-C)
Authors: Rahmi Yannisa Mutiara , Ihsan Indra , Indra Beni , Yani Finny Fitry , Rofinda Zelly Dia
Published: March 2024

Latar Belakang: Multisystem Inflammatory Syndrome in Children (MIS-C) merupakan respon inflamasi yang melibatkan  > 2 organ pasca infeksi SARS-CoV-2. Pemeriksaan marker inflamasi dapat membantu klinisi dalam menegakkan diagnosis dan memprediksi luaran buruk, seperti kejadian syok. Laju endap darah (LED) merupakan marker inflamasi yang murah dan mudah dilakukan di layanan primer yang memiliki keterbatasan fasilitas.
Objektif: Mengetahui hubungan LED dengan kejadian syok pada pasien MIS-C yang dirawat di RSUP Dr. M. Djamil Padang.
Metode: Jenis penelitian ini adalah analitik retrospektif dengan menggunakan data rekam medis pasien yang memenuhi kriteria inklusi dan eksklusi. Penelitian dilakukan di RSUP Dr. M. Djamil Padang pada pasien yang didiagnosis MIS-C sesuai kriteria World Health Organization (WHO). Data kemudian dianalisis dengan uji Mann-Whitney.
Hasil: Penelitian ini mendapatkan median LED adalah 25,5 (1-117) mm/jam pada pasien MIS-C. Sebanyak 43,8% pasien mengalami syok. Uji statistik Mann-Whitney menunjukkan bahwa tidak terdapat perbedaan yang signifikan antara nilai LED pada pasien MIS-C yang mengalami syok dengan yang tidak (p = 0,055).
Kesimpulan: Median LED pada pasien MIS-C ditemukan meningkat melebihi batas normal. Pasien MIS-C yang mengalami syok memiliki median nilai LED yang lebih tinggi jika dibandingkan dengan yang tidak (43 vs. 19,5 mm/jam), namun tidak terdapat hubungan yang signifikan antara nilai LED dengan kejadian syok pada pasien MIS-C. Pemeriksaan LED tidak dianjurkan untuk digunakan dalam memprediksi kejadian syok pada pasien MIS-C.
Kata kunci: Laju Endap Darah, Luaran, MIS-C, SARS-CoV-2, Syok
Hubungan Kanker Payudara Tripel Negatif dengan Kejadian Metastasis Aksila dan Metastasis Jauh di RSUP Dr. M. Djamil Padang
Authors: Nindita Priska Audina , Handayani Tuti , Suchitra Avit , Khambri Daan , Mulyani Henny , Rustam Erlina
Published: March 2024

Latar Belakang: Lebih dari 90% kematian terkait kanker payudara disebabkan oleh tumor sekunder di organ yang jauh akibat metastasis. Kanker payudara tripel negatif atau triple negative breast cancer (TNBC) merupakan subtipe paling agresif diantara subtipe lainnya. Secara klinis TNBC memiliki ukuran tumor yang lebih besar, melibatkan kelenjar getah bening, dan memiliki derajat keganasan yang lebih buruk. Pasien TNBC lebih berisiko mengalami metastasis dan kematian dibandingkan dengan jenis subtipe lainnya sehingga prognosisnya juga lebih buruk.
Objektif: Mengetahui hubungan kanker payudara tripel negatif dengan kejadian metastasis aksila dan metastasis jauh di RSUP Dr. M. Djamil Padang.
Metode: Penelitian analitik observasional dengan desain penelitian cross-sectional bersifat retrospektif. Jumlah sampel penelitian sebanyak 11 pasien TNBC dan 99 pasien non-TNBC di RSUP Dr. M. Djamil Padang tahun 2016 – 2021. Digunakan analisis uji Chi Square.
Hasil: Kejadian metastasis aksila pada pasien TNBC sebesar 45,5% dan kejadian metastasis jauh sebesar 90,9% dengan lokasi metastasis terbanyak pada organ paru. Tidak terdapat hubungan antara kanker payudara tripel negatif dengan kejadian metastasis aksila (p=0,071) dan terdapat hubungan bermakna antara kanker payudara tripel negatif dengan kejadian metastasis jauh (p=0,018).
Kesimpulan: Penelitian ini dapat disimpulkan bahwa tidak terdapat hubungan antara kanker payudara tripel negatif dengan kejadian metastasis aksila dan terdapat hubungan antara kanker payudara tripel negatif dengan kejadian metastasis jauh.
Kata kunci: kanker payudara, tripel negatif, metastasis
Pengaruh Suplementasi Vitamin D Terhadap Perubahan Skor Psoriasis Area and Severity Index (PASI) Pada Pasien Psoriasis: Studi Kasus Dengan Pendekatan Berbasis Bukti
Authors: Rahmawati Anni , Lestari Wiji
Published: March 2024

Latar Belakang: Psoriasis merupakan suatu penyakit autoimun dan inflamasi kulit yang bersifat kronis. Perjalanan penyakit psoriasis membuat kualitas hidup pasien menurun dan meningkatkan mortalitas. Vitamin D memiliki peran penting dalam fungsi kekebalan tubuh dengan meningkatkan respons imun bawaan dan adaptif. Efek suplementasi vitamin D masih menjadi perdebatan karena hasil yang tidak konklusif.
Objektif: Mengetahui efek pemberian suplementasi Vitamin D terhadap perubahan skor Psoriasis Area and Severity Index (PASI) pada pasien psoriasis.
Metode: Penelusuran literatur dilakukan pada empat pangkalan data, yaitu PubMed, Cochrane, ProQuest, dan Embase menggunakan kata kunci MeSH terms. Penyeleksian artikel dilakukan dengan penapisan judul atau abstrak, telaah teks lengkap, dan menentukan terpenuhinya kriteria inklusi dan eksklusi. Dilakukan telaah kritis pada dua studi kajian literatur sistemik/meta-analisis dari uji acak terkontrol berdasarkan telaah validity, importance, dan applicability.
Hasil: Dua literatur dipilih dan dinilai secara kritis. Artikel pertama menunjukkan bahwa tidak terdapat perbedaan skor PASI antara pasien psoriasis yang mendapat plasebo dengan pasien psoriasis yang mendapatkan suplementasi vitamin D setelah 3, 6, dan 12 bulan pemberian suplementasi. dengan p>0,05. Pada artikel kedua, suplementasi vitamin D lebih unggul dibandingkan plasebo dalam memperbaiki skor PASI setelah 6 bulan intervensi (MD = -0,92, 95% CI = -1,72 hingga -0,11). Namun setelah penyesuaian Hartung-Knapp, hasil menjadi tidak signifikan (MD = 0.92, 95% CI = 2.21 hingga 0.38).Suplementasi Vitamin D tidak menurunkan keparahan pada psoriasis yang dinilai melalui PASI.
Kesimpulan: Pemberian suplementasi vitamin D tidak memberikan pengaruh terhadap perbaikan keparahan pada pasien psoriasis yang dinilai melalui skor PASI.
Kata kunci:  Vitamin D, Psoriasis, keparahan psoriasis, PASI
Liberdade econômica e valorização do trabalho: entre o paradigma da flexibilização e os ditames da justiça social
Authors: Furlaneto Fernanda , Bagnoli Vicente , Parola Del Boni Ramos Palloma
Published: March 2024

O presente artigo propõe debater a relação entre liberdade econômica e trabalho. É possível preservar a ordem econômica flexibilizando a valoração do trabalho humano para o desenvolvimento nacional? De um lado, a necessidade da atuação do Estado na limitação de eventuais abusos do poder econômico, com a regulação de normas de proteção em matéria trabalhista e a valoração do trabalho humano. De outro lado, a partir de análises com ênfase ao direito econômico do trabalho e comparado, verificou-se que, o Brasil migrou para flexibilizações assim como outros países participantes da Organização Internacional do Trabalho. As flexibilizações, de certo modo, contribuíram para o surgimento de uma classe precarizada, a persistência do desemprego e a intensificação das desigualdades sociais. Assim, pelo método hipotético dedutivo a partir de pesquisas bibliográficas e jurisprudenciais, o objetivo deste artigo não é traçar soluções definitivas, mas sim apontar que livre iniciativa e trabalho pertencem a uma mesma ordem econômica, de modo que o ponto de equilíbrio entre si, é possível com a valorização do trabalho humano e o efetivo exercício da soberania pelo Estado.
PEMAKNAAN DAN IMPLEMENTASI PRINSIP EX AEQUO ET BONO DALAM PENYELESAIAN SENGKETA EKONOMI SYARIAH MELALUI BASYARNAS
Authors: Umam Khotibul , Nasution Muhammad Guntur Hamonangan Nasution
Published: March 2024

The dispute resolution mechanism in BASYARNAS, an Islamic economics arbitration institution, is based on the principle of ex aequo et bonowhich still raises questions regarding its interpretation and implementation. This research aims to comprehend the meaning, limitations, and implementation of the ex aequo et bono principle in the decisions of BASYARNAS. This study uses a normative legal research method with statutory, conceptual, and case study approaches. The findings show that the interpretation of the ex aequo et bono principle correlates with Sharia principles in terms of rules and principles, prohibition of ultra petita, and arbitrator's capability. Meanwhile, the limitations of the application of ex aequo et bono are closely related to the consensual principle of the parties, primary petitum demands, Sharia principles, pacta sunt servanda, and the principle of good faith. These concepts will be taken into account in reviewing the nullity of a contract and its consequences thereafteer. In addition, the implementation, as seen in the Decision of BASYARNAS Case No. 01/Year 2010/BASYARNAS, shows that fair and propriety assessment of the panel does not solely arise from the phrase ex aequo et bono. The decision also negates the elements of the agreement and the good faith of the parties as a basis for continuing an existing contract.
A study to assess the prevalence and risk factors for Clostridioides difficile infection in patients with inflammatory bowel disease in a tertiary care hospital in Northern India
Authors: Ghoshal Ujjala , Singh Romya , Tejan Nidhi , Sahu Chinmoy , Pandey Ankita , Ghoshal Uday C.
Published: March 2024

Objectives:

The prevalence of Clostridioides difficile infection (CDI) is on rise among patients with inflammatory bowel disease (IBD). This study sought to describe the prevalence and risk factors of CDI in patients with IBD as compared to non-IBD controls.

Materials and Methods:

This was a prospective study conducted at a Department of Microbiology in collaboration with a Department of Gastroenterology. The patients with IBD and controls without IBD presenting with diarrhea were included in the study. The screening test for C. difficile infection was done by glutamate dehydrogenase (GDH) assay and toxin detection by enzyme-linked immunoassay (ELISA). Anaerobic culture for C. difficile was done on a selective cycloserine cefoxitin fructose agar and polymerase chain reaction (PCR) was done for Toxin A (TcdA) and Toxin B (TcdB) gene detection. C. difficile infection was confirmed if GDH and toxin ELISA or PCR were positive.

Statistical Analysis:

Data were analyzed with the Statistical Package for the Social Sciences version 20.0.The numerical variables were presented by means and standard deviations. Comparison of continuous variables was done using Student’s t-test. Categorical variables were analyzed by Chi square test. P<0.05 was considered to be statistically significant.

Results:

A total of 160 cases and 112 age- and gender-matched control were included in IBD group and nonIBD group, respectively. Only one culture was positive, 12 and six were positive for GDH ELISA and TcdA and TcdB ELISA, respectively, and 7 were positive by PCR for toxin genes. The factors found significantly associated with CDI were proton-pump inhibitors use (P = 0.001), levofloxacin (P =0.001), and azathioprine (P =0.042). Using PCR as a reference method for C. difficile toxin detection, the sensitivity, and specificity of GDH ELISA and ELISA for toxins were 100%, 96.8% and 85.7%, and 100%, respectively.

Conclusions:

The prevalence of CDI among patients with IBD has been found to be low, that is (only 4.4%) in this study population.
Analysis of Syntactic Material in the Textbook of SDN 03 Cemaka Putih Class 1-3
Authors: Agustin Arni Fitriani Dwi , Fadhilah Muhammad Yaasiin , Nuryani Nuryani
Published: March 2024

This research is entitled "Analysis of Syntactic Material in Textbook Material at SDN 03 Cempaka Putih Grades 1-3." Many people do not know that syntactic material has also been studied since elementary school, therefore the researcher decided to conduct this research. The purpose of this research is to find out what material is related to syntax in class 1-3 textbooks at SDN 03 Cempaka Putih. This type of research is descriptive qualitative. The data collection technique was carried out through observation by borrowing textbooks from grade 1-3 teachers at SDN 03 Cempaka Putih and carrying out reading, listening and note-taking techniques. The subject of this study is the syntactic material contained in the textbooks used at SDN 03 Cempaka Putih grades 1-3. The results showed that of the 17 textbooks used at SDN 03 Cempaka Putih grades 1-3, there were 9 materials related to syntax. The material found in the textbooks used at SDN 03 Cempaka Putih grades 1-3, namely words and sentences.
Developing Mobile-Assisted Language Learning (MALL) Materials for ESL Learners
Authors: Sanjaya Eko
Published: March 2024

The development of technology has brought significant impacts on education. This creates much potential for the teaching and learning of English as a second language. With the great capability of the internet, educators can design powerful materials for efficient and effective learning. Mobile-assisted Language Learning (MALL) has become one of the popular research areas on technology in education in recent years for its advantages of flexibility of time and place. However, much only focus on a single application or platform implementation for the learning. This proposed study intends to integrate multiple internet-based platforms to support ESL learning. It aims to develop attractive and interactive learning materials that utilize Mobile-assisted Language Learning. This research uses the ADDIE method in developing the materials. To evaluate the materials, Technology Acceptance Model (TAM) will be adopted to investigate the participants’ perceptions of their experience of using the MALL materials. The participants of the study will be 7th-grade students of SMPN 4 Satap Sejangkung. These materials are planned to be a product that can make use of the advantages of mobile devices, in this case, flexibility and usability.
Analysis Of the Application of Foreign Curriculum for Kindergarten Students
Authors: Lee Anasthasia
Published: March 2024

This study aims to assess the application of Pearson curriculum for kindergarten students. Because, instead of using K-2013, international schools in Indonesia have been applying foreign curriculum. The findings of this study revealed Indonesian international school kindergarten students achieved more in terms of acquiring a second language and have more cultural knowledge and understanding. This analysis can be used a source for another schools or teacher to evaluate the curriculum applied in the school.
Maternal Age at the Last Birth and the Risk for Breast Cancer: A Case Control-Retrospective Study and Mini-Review of the Literature
Authors:   University of West Attica (UniWA), Athens, Greece, Bothou Anastasia , Zervoudis Stefanos ,   University of West Attica (UniWA), Athens, Greece, Nikolettos Konstantinos ,   Department of Obstetrics and Gynecology, Democritus University of Thrace, Greece, Gerede Aggeliki ,   Department of Obstetrics and Gynecology, Democritus University of Thrace, Greece, Tsikouras Panagiotis ,   Department of Obstetrics and Gynecology, Democritus University of Thrace, Greece
Published: March 2024

Objective: Maternal age at the last birth and the risk of developing breast cancer were subjects of epidemiologic research, with controversial results. In order to objectively assess the relationship between maternal age at the last birth and the risk of developing breast cancer, we carried out this case control-retrospective study. Material and Methods: In our case-control retrospective analysis, 342 women who visited two breast clinics in Greece and had given birth to live newborns were analyzed. Women with breast cancer were included in the case group, whereas women without the disease were included in the control group. All women underwent a clinical examination that included a breast ultrasound and, in those who were older than 40 years old, also a digital bilateral mammogram was performed. Results: Mann-Whitney test observed that p-value = 0.474 and concluded that there is no statistically significant difference in the distributions of maternal age at birth of the last child of the two groups of women and the risk of breast cancer development. Conclusion: Our study showed no statistically significant relationship between maternal age at the last birth and breast cancer. Further studies with a larger number of patients are mandatory in order to confirm this result.
Childbirth on a Moderately Shrinked Pelvis at the Institut D’hygiene Sociale Hospital in Dakar
Authors:   Department of Gynecology & Obstetrics, Institute of Social Hygiene Hospital of Dakar, Senegal, MM Niang , AM Wade ,   Department of Gynecology & Obstetrics, Institute of Social Hygiene Hospital of Dakar, Senegal, F Samb ,   Department of Gynecology & Obstetrics, Institute of Social Hygiene Hospital of Dakar, Senegal, CT Cisse ,   Department of Gynecology & Obstetrics, Institute of Social Hygiene Hospital of Dakar, Senegal
Published: March 2024

Objectives: To assess the frequency of moderately narrowed pelvises, to specify the epidemiological and clinical profile of parturients, the mode of childbirth and to evaluate the maternal and neonatal prognosis in patients who underwent a trial of labour at the IHS hospital between the January 1st, 2019 and December 31st, 2020. Patients and Methods: This was a descriptive and analytical retrospective study of all patients who underwent a trial of labour at the Gynaecology-Obstetrics Department of the IHS Hospital in Dakar between January 1st and December 31st, 2020, i.e. a period of 12 months. Data were collected from birth records. Data entry was performed with EPI INFO 7 software and analysis with SPSS 21 software. Results: During the study period, we performed 101 labour trials among the 2156 childbirths, a frequency of 4.6% of childbirths. The epidemiological profile of the patients was that of a primiparous woman (73.3%) with an average age of 24, married (96.9%), having carried out at least 3 prenatal consultations (90%) and carrying a pregnancy at term (97%). Clinically, the average fundal height was 33 cm with extremes of 27 and 40 cm. The majority of patients (73.3%) had a borderline pelvis while the transversely narrowed pelvis accounted for only 26.7% of cases. The introductory palpation was only performed in 17 patients (16.8%) and it was doubtful in 11 of them (10.9%). The trial of labour ended in vaginal childbirth in 34.7% of cases or in caesarean section in 65.3% of patients. Failure of the trial of labour was more frequent in nulliparous (76.9%) compared to primiparous (64.9%), pauciparous (72.7%) (p=0.082) and in patients with borderline pelvis (79.5%) compared to those who had a transversely narrowed pelvis (68.7%) (p=0.392). In our series, 12 new-borns (11.9%) had benefited from neonatal resuscitation and eleven of them, that is a rate of 10.8%, were transferred to a neonatology unit. These were cases of non-reassuring fetal status occurring during the expulsive phase. Their evolution was favourable in all cases. One early neonatal death (1%) was recorded. No maternal complication had been notified. Conclusion: Childbirths on a moderately narrowed pelvis are not uncommon in our practice. They require a prior clinical evaluation of the parturients, particularly with the introducer palpation in order to increase the chances of a favourable outcome and to avoid maternal and perinatal complications.
Application of in Vitro Membrane Pulmonary Oxygenation Technology (ECMO) in Neonatal Respiratory Failure
Authors:   The Affiliated Zhongshan Hospital, Sun Yat-sen University, China, Li Liyu , Chen Jingguo ,   The Affiliated Zhongshan Hospital, Sun Yat-sen University, China, Li Qiaoru ,   The Affiliated Zhongshan Hospital, Sun Yat-sen University, China, Yuan Rukang ,   The Affiliated Zhongshan Hospital, Sun Yat-sen University, China, Wu Tingbo ,   The Affiliated Zhongshan Hospital, Sun Yat-sen University, China, Zheng Kaijun ,   The Affiliated Zhongshan Hospital, Sun Yat-sen University, China, Xu Wenjing ,   The Affiliated Zhongshan Hospital, Sun Yat-sen University, China, Li Yijuan ,   The First Affiliated Hospital, Sun Yat-sen University, China
Published: March 2024

Objective: To explore the application of Extracorporeal Membrane Oxygenation technology (ECMO) in neonatal respiratory failure and provide guidance for future ECMO technology for critically ill newborns. Methods: Retrospective analysis of the basic data, ECMO support process, and long-term neurological development of nine children supported by ECMO at Zhongshan People’s Hospital from January 2015 to August 2021. Results: From January 2015 to August 2021, the number of admissions to the neonatal department of our hospital was 10,325, with 433 cases of neonatal respiratory failure, which was in line with ECMO support indication of 21 cases, of which 12 were non-ECMO groups and 12 were ECMO groups. In nine cases, the differences in sex, birth weight, gestational age, birth pattern, Apgar score, NCIS score, OI value, hospitalization days, mortality rate, and incidence of intracranial bleeding were not statistically significant (P>0.05). However, the average daily hospitalization cost for children in the ECMO group was significantly higher than that in the non-ECMO group, and the difference was statistically significant (P<0.05). ECMO after 12 h operation, arterial oxygen pressure, and intravenous oxygen saturation are substantially enhanced, while arterial carbon dioxide pressure oxygenation index is considerably reduced, with a statistically significant difference (P<0.05). ECMO pre-operation survival group lactic acid (6.46±2.70) was lower than the death group (17.66±14.62), after operation lactic acid decreased significantly, and after ECMO operation of the death group lactic acid showed an increase in conductivity. During the early stage of ECMO establishment, PT and APTT rapidly rise, while FIB decline. The ACT of both groups of children increased in the early stages of ECMO establishment and then gradually declined. In the ECMO group, seven children survived to discharge, six had no neurological developmental problems, and one had residual neurological sequelae. Conclusion: ECMO can be employed as a complementary supportive treatment for newborns with respiratory failure, and the oxygenation condition can be effectively improved for newborns with respiratory failure who have failed to respond to traditional treatment.
Antiphospholipid Syndrome (APS) and Successful Pregnancy Outcome: A Case Report
Authors:   University Clinic of Gynecology and Obstetrics, Medical Faculty, Skopje, R North Macedonia, Bejta Albina , Purrini Rina ,   University Clinic of Gynecology and Obstetrics, Medical Faculty, Skopje, R North Macedonia, Gjoreski Josif ,   University Clinic of Gynecology and Obstetrics, Medical Faculty, Skopje, R North Macedonia, Jegeni Lorik ,   University Clinic of Gynecology and Obstetrics, Medical Faculty, Skopje, R North Macedonia, Shabani Hylja ,   University Clinic of Gynecology and Obstetrics, Medical Faculty, Skopje, R North Macedonia
Published: March 2024

Antiphospholipid Syndrome (APS) is an autoimmune multisystemic disorder characterized clinically by recurrent thrombosis and pregnancy morbidity and serologically by the presence of Antiphospholipid antibodies (aPL) including Anticardiolipin (aCL) and anti-2glycoprotein I (anti-2GPI) antibodies and Lupus Anticoagulant (LA). Diagnosis requires a high index of suspicion during evaluation of women with recurrent pregnancy loss and vascular thrombosis. Low dose aspirin combined with heparin can reduce morbidity and improve the pregnancy outcome. Here we report a case of a 32 year old lady having APS who presented with arthritis, recurrent miscarriages and venous thrombosis.
Uterine Rupture: A Literature Review and Case Presentation Highlighting Diagnostic and Clinical Challenges Posed by this Rare and Potentially Catastrophic Obstetric Emergency
Authors:   Department of Obstetrics & Gynaecology, Mildura Base Public Hospital, Australia, A Aboda , K Kathawadia ,   Department of Obstetrics & Gynaecology, Mildura Base Public Hospital, Australia, B McCully ,   Department of Obstetrics & Gynaecology, Mildura Base Public Hospital, Australia
Published: March 2024

Uterine rupture is a rare but life-threatening condition, with incidence ranging from 1 in 5,700 to 1 in 20,000 pregnancies. It is an obstetrical emergency requiring rapid intervention to mitigate harm and allow the best possible chance of survival for mother and baby. While the most frequent antecedent is scar dehiscence associated with previous uterine surgeries such as caesarean section or, less commonly, myomectomy or curettage, other non-iatrogenic aetiologies must also be considered to allow a fully inclusive approach sufficient to spur acute clinical care. This review highlights these factors and the limitations of diagnostic imaging modalities in an acute management setting. It aims to accrue the importance of broad clinical suspicion and pre-emptive action in patients presenting with pain during pregnancy regardless of predisposing risk and the assurances of non-interventional scanning. We offer this review to share an experience of clinical care and improve knowledge and understanding to improve future patient care.
Role of Phytoconstituents in the Aloe-Mediated Nanoparticles
Authors:   Department of Chemistry, College of Natural and Computational Sciences, Mekdela Amba University, Tulu Awuliya, Ethiopia, AT Yadeta
Published: March 2024

Currently, green, single-pot biomimetic, and/or biological methods of Nanoparticle (NP) synthesis are preferred over chemical and physical methods because of their rapidity, eco-friendliness, non-pathogenicity, and economic attributes. In addition, these biosynthesis methods exclude the use of high temperature, energy, pressure, and toxic chemicals. Through biosynthetic methods, nanotechnology is related to biotechnology. This has advanced nanobiotechnology which is the development of eco-friendly and biosynthetic nanomaterials/nanoparticles. Therefore, nowadays, biogenic or green synthesis of NPs using plants has emerged as a potential nano-factory, and their applications are based on phytochemicals. The chemical constituents identified in Aloe plants include vitamins, minerals, enzymes, polysaccharides, fatty acids, indoles, hydrocarbons, carboxylic acids, aldehydes, ketones, phenolic compounds, phytosterols, pyrimidines, alkaloids, etc. Each of these chemicals has potential biological activities that make them essential for in nanotechnology. Aloe phytochemicals play a crucial role in the fabrication of Aloe-based NPs by acting as reducing, capping, and stabilizing agents that control the shape and size of the formed NPs. In addition, these phytochemicals play a significant role in the applications of Aloe-based NPs owing to their biological properties. Moreover, it is important to understand the role of phytoconstituents from different Aloe species and in every part of the plants using nanotechnology.
Biomedical Relevance of Biological Smart Materials Approach for Synthesis of Selenium Nanoparticles by Agrobacterium
Authors:   Department of Zoology, Govt Girls PG College, Ujjain, MP, India, Kumar Anil , Saxena Shikha ,   Department of Zoology, Govt Girls PG College, Ujjain, MP, India, Shrivastawa GM ,   Department of Botany, Govt Tilak PG College, Katni, MP, India, Hanote Rajesh ,   Department of Zoology, Motilal Govt. Science College, Bhopal, MP, India, Chauhan Rajendra ,   Department of Zoology, Motilal Govt. Science College, Bhopal, MP, India, Pal Preetibala ,   Department of Biotechnology, Microbiology, JH Govt PG College, Betul, MP, India, Bhawsar Niharika ,   Department of Biotechnology, Microbiology, JH Govt PG College, Betul, MP, India, Chaukikar Rajkumar ,   Department of Biotechnology, Microbiology, JH Govt PG College, Betul, MP, India, Bathari Khushbu ,   Department of Microbiology, BU, Bhopal, MP, India, Singh Bijendar ,   Department of Chemistry, HBTU, Kanpur, UP, India
Published: March 2024

Nanotechnologies are making more efforts to develop new materials to use in different ways to be beneficial to human life. Their unique properties are constantly being improved to enhance more effective and perfect activity as per the requirement. Researchers are continuously producing highly useful materials with the help of different types of microorganisms and green technology for the synthesis of nanoparticles as per the requirement. Primarily Agrobacterium species are the most useful microorganisms for the synthesis of selenium nanoparticles in the diameter range of nanoscale. These are capable and more effective in making nanomaterials from selenium to use in medicinal and other applications. These are opening a new dimension in the field of medical science which is beneficial for multipurpose use directly or indirectly.
The Optimum Size of K-Wires for Fifth Metacarpal Neck Fractures: Double 1.6 mm K-Wires Antegrade Intramedullary Nailing Technique
Authors:   Department of Hand and Plastic Surgery, The firstpeople’s Hospital of Lingping District, China, W Kaymin , C Rong ,   Department of Hand and Plastic Surgery, The firstpeople’s Hospital of Lingping District, China, H Youwu ,   Department of Hand and Plastic Surgery, The firstpeople’s Hospital of Lingping District, China, L Gang ,   Department of Hand and Plastic Surgery, The firstpeople’s Hospital of Lingping District, China, Z Xingqun ,   Department of Hand and Plastic Surgery, The firstpeople’s Hospital of Lingping District, China, Y Yi ,   Department of Hand and Plastic Surgery, The firstpeople’s Hospital of Lingping District, China, W Zipu ,   Department of Surgery; Lu’an Hospital of Anhui Medical University, China, H Lijiang ,   Department of Orthopedic Surgery; Second People’s Hospital of Yuhang District, China, W Liang ,   Department of Hand and Plastic Surgery, The firstpeople’s Hospital of Lingping District, China
Published: March 2024

Objective: Previous researches did not pay significant attention to the 5th metacarpal’s intramedullary diameter. This research aims to determine the optimal K-wires for 5th metacarpal neck fractures based on the narrowest part of 5th metacarpal. Methods: We retrospectively studied 31 patients with fifth metacarpal neck fractures. All patients underwent Intramedullary (IM) nailing surgery with two 1.6 mm K-wires. The narrowest part of the fifth metacarpal was measured preoperatively based on CT scan. Quick-DASH was assigned to be the primary outcome, pain, satisfaction, motor function and complications were also recorded. Results: Well reductions were observed in all patients. QuickDASH sore was median 0 with the range of 0-32, pain score was median 0 with the range of 0-2, VAS satisfaction was median 5 with the range of 3-5 at the endpoint. Grip strength, metacarpophalangeal joint and total active motion were improved immediately after operation. Two patients remained persistent paresthesia, and three patients experienced persistent pain at the endpoint with the VAS score of 1, 2, 2. Conclusion: The use of double 1.6 mm K-wires antegrade intramedullary nailing could be an optimum option for patients with fifth metacarpal neck fractures.
Beyond Ridge Regression: Enhancing Distribution of Relaxation Times Deconvolution
Authors: Py Baptiste , Ciucci Francesco
Published: March 2024

The distribution of relaxation times (DRT) has emerged as a promising method for analyzing electrochemical impedance spectroscopy (EIS) data. The standard approach for reconstructing the DRT from measured impedances consists of regularized regression, which usually leverages the Euclidean norm. In this work, we show for the first time that the 1-norm is often more accurate than ridge regression and the infinity-norm. We also demonstrate that the 1-norm is more robust against discontinuities in the DRT and outliers in the impedance data. Overall, this work is expected to enhance regularized regression of non-parametric methods when analyzing EIS spectra.
Identification of Readily Available Pseudo-Natural Products
Authors: Pahl Axel , Grygorenko Oleksandr O. , Kondratov Ivan S. , Waldmann Herbert
Published: March 2024

Pseudo-natural products (PNPs) combine fragments derived from NPs in ways that are not found in nature, and may lead to the discovery of novel chemotypes for unexpected targets or the identification of unprecedented bioactivities. PNPs have increasingly been explored in recent drug discovery programs, and are strongly enriched in clinical compounds. We describe how a large number of structurally different PNPs can be accessed readily and without the need to execute labor- and time intensive synthesis programs. We employed an improved version of the previously reported natural product fragment combination (NPFC) tool to analyze the full library of 3.5M synthetic small molecules and screening libraries from Enamine for PNP content, assessed the spatial complexity of Enamine-PNPs using the recently developed normalized Spatial Score (nSPS) and evaluated the bioactivity of a selected subset of Enamine-PNPs in the unbiased morphological cell painting assay. A major fraction (32%; 1.1 million compounds) of the Enamine library are PNPs which contain a significant number of compounds with unexpected and probably new bioactivity.
Porous molecular crystals derived from cofacial porphyrin/phthalocyanine heterodimers.
Authors: Stamos Nikolaos-Angelos , Kerrigan Shannah , Stiven Alexander , Nichol Gary , Bezzu C. Grazia , Burt Luke , Moggach Stephen , Turner Gemma , McKeown Neil
Published: March 2024

Porphyrin-based porous materials are of growing interest as heterogeneous catalysts especially for reactions that are of importance to sustainability. Here we demonstrate that porous molecular crystals can be prepared by the simple co-crystallisation of tetraphenylporphyrin (TPP) with octa(2’,6’-di-iso-propylphenoxy)phthalocyanine and its metal complexes [(dipPhO)8PcM; M = H2, Al-OH, Ti=O, Mn-Cl, Fe-Cl, Co, Ni, Cu, Zn, Ga-Cl, Ag, In-Cl or Au-Cl]. This process is facilitated by the efficient formation of the supramolecular heterodimer between TPP and (dipPhO)8PcM, which is driven by the complementary symmetry and shape of the two macrocycles. The (dipPhO)8PcM component direct the crystal structure to form Phthalocyanine Nanoporous Crystals (PNCs) of similar structure to those formed by (dipPhO)8PcM alone. The incorporation of TPP appears to partially stabilise the PNCs towards the removal of included solvent and for cocrystals containing (dipPhO)8PcCo stability can be enhanced further by the in-situ addition of 4,4-bipyridyl to act as a “molecular wall tie”. These stabilised PNC/TPP cocrystals have a Brunauer-Emmett-Teller surface area (SABET) of 454 m2 g-1 and a micropore volume (Vmp) of 0.22 ml g-1. The reactivity of both macrocycles within the PNC/TPP co-crystals are demonstrated by in-situ metal insertion.
Study of Synthesis ,Characterisation and Antibacterial activity of Silver nanoparticles derived from roots of Phyllanthus emblica.
Authors: Bordiwala Rashmi , Yamgar Ramesh
Published: March 2024

In this study, synthesis of silver nanoparticles(AgNP’s) is discussed using aqueous extract of roots of Phyllanthus emblica. Synthesised AgNP’s showed maximum wavelength at 267 nm after 30 minutes of synthesis. Fourier Tranform Infrared (FTIR) Spectroscopy results are obtained giving functional groups responsible in formation of metal nanoparticles. Field Emission Gun -Scanning Electron Microscopy (FEG-SEM) showed particle size in the range of 30.0 nm, 37.5 nm and 35.6 nm for AgNP’s .Whereas, Energy dispersive X-Ray spectroscopy (EDS) technique also determined composition of metal nanoparticles formed. Futher , antibacterial activity is highlighted using synthesised AgNP .
Motives for Choosing a Profession of Service-Operational and Military Orientation among School Graduates
Authors:   Vologda Institute of Law and Economics of the Federal Penitentiary Service, Udaltsova M.O. , Dobryakova V. A. ,   Vologda Institute of Law and Economics of the Federal Penitentiary Service
Published: March 2024

The article considers the study of motives of upper secondary education students for their professional identity. The article provides the rationale for studying main motives behind the appropriate choice of a profession by senior students. The empirical enquiry has revealed that the graduates choosing the professions dealing with performing operational tasks the main motives for choosing the profession, though not typical for most students, are “dynastic choice”, “situated and pragmatic choice”, and “free choice”. It has been found that among the students who have made their choice in favor of military professions and those who haven’t there is almost equal number of graduates with a middle level of professional military motivation. The study has found the correlation between the following motives for profession choice: “parental influence”, “dynastic choice”, “free choice”, “subject choice”, “television factor”, and the level of professional military motivation. The results of the study help to identify further steps in helping students make a meaningful choice of a profession.
Psychological Aspects of the Perceptions of Subjective Loneliness (The Study of the Sample of Russian Citizens)
Authors:   State University of Education, Kononov A. N. , Ishchenko M. E ,   State University of Education
Published: March 2024

The article presents the results of the study of perceptions of subjective loneliness by Russian citizens. The sampling included 146 people, 51 of whom were men and 95 women. The age of the respondents was 17-46, so the average age was 32. The content analysis method has revealed main criteria indicating that subjective loneliness is perceived as abandonment and powerlessness with negative emotions prevailing. Experiencing real loneliness, the subjects are prone to reflect about their immediate environment. Subjects’ thoughts of loneliness they are likely to experience in the future are associated with the feeling of fear and the urge to avoid possible loneliness. Reluctance to become aware of the causes behind the feeling of loneliness and the urge to avoid this feeling leads to greater negative feelings when respondents actually experienced it.
Interrelation of Loneliness Experience and Cognitive Biases of University Students
Authors:   Perm State National Research University, Prodovikova A. G. , Uzhegova A. A. ,   Perm State National Research University
Published: March 2024

The article presents the results of the study of the correlation between loneliness experience and cognitive biases of university students. It has revealed the interrelation between the index of general loneliness with dysfunctional attributes and basic views. The regression analysis has found that on the one hand, the conviction that the outer world is hostile and people are mean, contributes to experiencing loneliness, and on the other hand, social communication addiction influences the development of cognitive biases. Thus, “lonely” students attribute the reasons of their loneliness to their personality traits, and tend to reason about their own shortcomings; they may prefer to stay alone and find something positive in it. “Not lonely” students, when experiencing loneliness, seek ways to communicate with somebody.
A modern approach to ergonomics: the study of work and non-work activities of employees
Authors:   University of Žilina, Zuzik Ján , Biňasová Vladimíra , Furmannová Beáta
Published: March 2024

The purpose of the study is to determine how an employee's work and non-work activities are related. The relevance of after-work activities is covered in the introduction. The relationship between employees' work and non-work activities is illustrated in the section that follows. The last section addresses the effects of employees' unequal workloads and non-work activities as well as suggestions for personalized advice. An individual's general well-being depends on having a balanced ratio between work and non-work activities, which is why the article offers a more comprehensive answer to this issue.
Acceptance and Practice to COVID-19 Vaccination Among Rural Population in Indonesia
Authors: Choirunnisa Rifda Amalia , Surya Darmawan Ede
Published: March 2024

As one of the strategies to prevent and reduce the spread of COVID-19 since January 2021, the Indonesian Government has implemented a COVID-19 vaccination program. When this research was carried out in the first semester of 2022, the achievement of COVID-19 vaccination target was not yet reach the expected target due to many people were afraid and refused to be vaccinated. The research aims to determine the acceptance and practice of COVID-19 vaccination in rural communities located in Banyumas Regency, Central Java in 2022. This was a cross-sectional study based on electronic survey data distributed to residents (aged ≥ 15 years) of Tunjung Village, Jatilawang Sub-district between May 27, 1 - June 10, 2022. The study sample size was 211 respondents using the quota sampling technique. We used the Health Belief Model (HBM) as the theoretical framework. The research results show that the majority (69%) of respondents stated that they received the COVID-19 vaccination and around 79.6% of those who received it had received the COVID-19 vaccination. Chi-square statistical analysis shows that the variables gender, education, knowledge about COVID-19, knowledge about COVID-19 vaccination, perceived severity of COVID-19, perceived benefits of COVID-19 vaccination, and perceived self-efficacy towards COVID-19 vaccination are related. significantly impact acceptance of COVID-19 vaccination. Perception of self-efficacy towards COVID-19 vaccination is the strongest driving factor for acceptance (POR: 5.45). In the multivariate test, the most dominant variable influencing vaccine acceptance was the variable perception of self-efficacy towards vaccination after controlling for the knowledge variable. A significant relationship was obtained between receipt of COVID-19 vaccination and COVID-19 vaccination practices. It was concluded that acceptance of COVID-19 vaccination is closely related to the level of knowledge and attitudes towards COVID-19 and COVID-19 vaccination, and the higher acceptance encourages the practice of carrying out COVID-19 vaccination. It is recommended that to increase acceptance and practice of Covid vaccination it is necessary to increase the population's knowledge regarding COVID-19 and the COVID-19 vaccine by increasing education and promotion of the COVID-19 vaccination program through electronic media, especially television and social media.
The Relationship Between Human Host and Environmental Factors on the Severity of Pneumonia Among Under-Five Children in West Java Province
Authors: Cahyani Nadia Regita Ayu , Wardani Hartati Eko , Alma Lucky Radita
Published: March 2024

Pneumonia cases in West Java Province 2018 were ranked first as the province with the highest number of cases in Indonesia with a prevalence of 58.80%. About 7-13% of severe pneumonia patients with an increased risk of death in children require intensive care. This study aims to determine the relationship between host and environmental factors on the severity of pneumonia in children under five years. The research method used cross-sectional study design approach. Data analysis techniques used chi-square, fisher's exact, and multiple logistic regression tests. The population in this study was 2,338 children under five years aged 12-59 months in West Java Province for the 2018 period, while the sample consisted of 132 respondents who met the inclusion criteria and were recorded in RISKESDAS 2018. The results showed that there was a significant relationship between host factors and the severity of pneumonia, namely prematurity (aOR= 2.446; 95% CI=1.113-5.376), while environmental factors that have a significant relationship on the severity of pneumonia, namely the habit of opening windows (aOR= 2.963; 95% CI=1.342-6.544). There is no relationship between Low Birth Weight (LBW), home ventilation conditions and lighting intensity. The most dominant factor in the severity of pneumonia is that the habit of opening windows does not meet the risk of 2.9 times higher severity of pneumonia in children under five years. This study concludes a relationship between prematurity and the habit of opening windows on the severity of pneumonia.
INNOVATIVE TECHNOLOGICAL TOOLS FOR TEACHING SITUATED ENTREPRENEURSHIP: A CASE STUDY IN A HIGHER EDUCATION
Authors: Hernández Maritza Arias , Virgüez Jesús Enrique Beltrán
Published: March 2024

Purpose: To present, through a case study, two technological tools for the playful-business teaching of entrepreneurship, one called the digital channel "cvivo.digital," and another of a curricular type called "Didactic Contents for Entrepreneurship."
 
Theoretical Framework: The Communication Revolution poses a challenge to one of the oldest and most persistent problems in the world, and technological tools represent determining factors in entrepreneurship processes (González et al., 2020).
 
Design/Methodology/Approach: As a methodological strategy, the phases of conceiving, designing, implementing, and operating (CDIO) were implemented. Although originally a teaching strategy in engineering, it is also applicable to research processes in other fields of knowledge. The stated stages were accompanied by documentary reviews, exercises of participant observation, and pilot testing, leading to the materialization of the technological tools.
 
Findings: The results highlighted the joint management and circulation of knowledge (students-teachers), functionality, usability, and portability of technological tools according to the real context of students and the current and growing challenges of entrepreneurship in Colombia.
 
Research, Practical & Social Implications: The article shows a path to promote and strengthen entrepreneurship in higher education by offering the pillars that can contribute to this important task for society.
 
Originality/Value: The results reflect an innovative way of addressing formative needs and promoting innovation, inviting reflection and experimentation with these forms of university work in various contexts.