bluuebunny/crossref_metadata_2025 huggingface dataset:
ABOUT UNCOUPLING OF CARS WITH COMMERCIAL DEFECTS IN RAILWAY TRANSPORT
Authors: Гордиенко Андрей Александрович
Published: July 2024

В статье подробно исследованы закономерности, связанные с отцепками вагонов с коммерческими неисправностями на железнодорожном транспорте. Определена структура отцепок вагонов с коммерческими неисправностями, выявленных после прохождения сортировочных горок. Приведено распределение отцепок вагонов с коммерческими неисправностями, угрожающими безопасности движения, по железным дорогам и станциям. Проанализирована динамика гарантийного расстояния перевозки грузов. Затронута проблема распределения ответственности за возникновение отцепок вагонов с коммерческими неисправностями по основным их причинам. Исследованы и определены основные параметры, связанные с устранением коммерческих неисправностей, требующих отцепок. Выполнен анализ структуры расходов, связанных с устранением коммерческих неисправностей на железнодорожном транспорте.

The article examines in detail the patterns associated with the uncoupling of cars with commercial defects in railway transport. The structure of uncoupling of cars with commercial defects identified after passing the marshalling humps is determined. The distribution of uncoupling of cars with commercial defects threatening traffic safety on railways and stations is given. The dynamics of the guaranteed distance of cargo transportation is analyzed. The problem of the distribution of responsibility for the occurrence of uncoupling of cars with commercial defects for their main reasons is touched upon. The main parameters related to the elimination of commercial defects requiring uncoupling are investigated and determined. The analysis of the structure of expenses related to the elimination of commercial defects in railway transport is carried out.
POLICY MEASURES TO MINIMIZE COMPETITIVE LAND TARIFFS IN THE DIRECTION OF CHINA WESTERN EUROPE
Authors: Бобрик Петр Петрович
Published: July 2024

Статья посвящена вопросам снижения сухопутных тарифов вдоль направления Китай Западная Европа до уровней, конкурентных с морской доставкой. Рассматриваются вопросы взаимного влияния интенсивности трафика и экономической эффективности коридора. Утверждается существование конкурентных тарифов при значительном росте трафика. Для запуска коридора показана необходимость минимизации длины маршрута и отсутствия горных участков. Рассмотрены вопросы организации единого перевозчика вдоль всего маршрута, придание ему на законодательном уровне одинакового статуса всеми странами транзитерами. Создание механизмов взаимовыручки стран с целью обеспечения устойчивости перевозочного процесса. Обсуждаются текущее состояние и перспективы решения политических вопросов сопровождения коридора.

The article is devoted to the issues of reducing overland tariffs along the China Western Europe route to levels competitive with sea delivery. The issues of mutual influence of traffic intensity and economic efficiency of the corridor are considered. The existence of competitive tariffs with a significant increase in traffic is claimed. To launch the corridor, the need to minimize the length of the route and the absence of mountain sections is shown. From these conditions, the only possible set of transit countries is determined. The issues of organizing a single carrier along the entire route are considered. Giving it the same status at the legislative level by all transit countries. Creation of mechanisms for mutual assistance of countries in order to ensure the sustainability of the transportation process. The current state and prospects of solving political issues of corridor maintenance are discussed.
MODELS AND METHODS OF STRATEGIC MANAGEMENT OF TRANSPORT INFRASTRUCTURE UNDER SANCTIONS
Authors: Цыганов Владимир Викторович , Савушкин Сергей Александрович
Published: July 2024

Рассмотрены проблемы и факторы, оказывающие существенное влияние на развитие транспортной инфраструктуры России (ТИ) в условиях санкций. Показаны место и роль действующих стратегических документов в процессе развития ТИ. Охарактеризованы основные направления развития ТИ в условиях санкций. Для поддержки принятия решений, связанных с таким развитием, предлагается использовать Комплекс моделей стратегического управления крупномасштабной ТИ, апробированный в процессе развития инфраструктуры Сибири, Дальнего Востока и Российской Арктики.

The problems and factors that have a significant impact on the development of the Russian transport infrastructure (TI) under the sanctions are considered. Showing the place and role of existing strategic documents in the development of TI. The main directions of TI development in the conditions of sanctions are characterized. To support decisionmaking related to such development, it is proposed to use the Complex of models for strategic management of large-scale TI, tested in the process of developing the infrastructure of Siberia, the Far East and the Russian Arctic.
GAME THEORY BASED ON BUILDING A RISK MODEL
Authors: Кузьмина Елена Витальевна
Published: July 2024

Рассмотрен принцип построения модели потерь на основе рисков. Предложено создание теоретико-игровой модели и оценена возможность ее использования на различных этапах процесса управления рисками ISO 27000.

The principle of constructing a risk-based loss model is considered. The creation of a game-theoretic model is proposed and the possibility of its use at various stages of the ISO 27000 risk management process is evaluated.
DEVELOPMENT OF THE SECURITY MANAGEMENT SYSTEM OF THE NORTHERN SEA TRANSPORT CORRIDOR
Authors: Гурлев Игорь Валентинович , Малыгин Игорь Геннадьевич
Published: July 2024

Проанализированы силы и средства управления и обеспечения безопасности транспортной системы «Северный морской транспортный коридор». Показаны направления развития, роль морских спасательных центров в организации и управлении действиями других федеральных ведомств, аварийноспасательных сил и средств в обеспечении безопасности на море, использование полярной авиации, спасательных вертолетов, беспилотных летательных аппаратов, космических аппаратов спутниковой навигации, информации и связи, боевых патрульных ледоколов, а также их взаимодействие с различными ведомствами и силовыми структурами в Арктике.

The article analyzes the forces and means of managing and ensuring the safety of the transport system "Northern Sea Transport Corridor". The directions of development, the role of marine rescue centers in organizing and managing the actions of other federal agencies, emergency rescue forces and means in ensuring safety at sea, the use of polar aviation, rescue helicopters, unmanned aerial vehicles, satellite navigation, information and communication spacecraft, combat patrol icebreakers, as well as their interaction with various departments are shown. and law enforcement agencies in the Arctic.
ON IMPROVEMENT OF THE OPERATION OF PASSENGER AND TECHNICAL STATIONS
Authors: Покровская Оксана Дмитриевна , Паршин Павел Константинович
Published: July 2024

Рассматривается комплекс мероприятий, направленных на совершенствование эксплуатационной работы пассажирских и технических станций, в частности, на оптимизацию маневровой работы. Показано, что технология организации маневровой работы по неиспользованным маршрутам позволит сэкономить продолжительность использования локомотивов и труда составителей поездов. Предлагается для ситуационной визуализации процессов использовать информационные доски для лиц, распоряжающихся маневрами.

He article presents considerations for improving the management structure of railway station complexes and passenger railway stations. It is shown that with the current organization of the vertical control system, it is advisable to combine passenger stations with local stations into one organizational unit. It is proposed to implement the organization of the work of railway station complexes and passenger railway stations on the principles of unity of command and personalization of responsibility.
PROPOSALS FOR IMPROVING THE LEGAL REGULATION OF CARGO ROAD TRANSPORTATION BY THE SELF-EMPLOYED
Authors: Ошорова Валерия Владимировна
Published: July 2024

Рассмотрены особенности осуществления грузоперевозок самозанятыми, проведен анализ затрат и финансовых результатов грузоперевозок в зависимости статуса перевозчика (работник по найму, индивидуальный предприниматель, физическое лицо или самозанятый при заключении различных договоров), обозначены проблемные вопросы осуществления перевозок грузов самозанятыми, даны предложения по внесению изменений в законодательство Российской Федерации.

The article considers the peculiarities of cargo transportation by self-employed, analyzes the costs and financial results of cargo transportation depending on the status of the carrier (employee, individual entrepreneur or selfemployed at the conclusion of various contracts), identifies problematic issues of cargo transportation by self-employed, gives proposals for amendments to the legislation of the Russian Federation.
INCREASING ENERGY EFFICIENCY AND ENVIRONMENTAL SAFETY OF POWER INSTALLATIONS OF MINING MACHINES
Authors: Кацуба Юрий Николаевич , Сафиуллин Равиль Нуруллович , Григорьева Людмила Владиславовна
Published: July 2024

Исследования направлены на решение практических задач с возможностью обоснования и разработки рекомендаций к применяемому топливу и его составным компонентам, для достижения требуемых характеристик энергетической эффективности, на этапах технологического производства и применения при функционировании энергетических установок горных машин. Проведенные исследования процессов и способов повышения энергоэффективности преобразования топлива в энергетических установках горных машин в совокупности с исследованием экологических показателей, позволили установить тесную взаимосвязь с качественными характеристиками применяемого топлива. Исследования проводились на экспериментальном комплексе в составе дизельной силовой установки и расчетно-регистрирующей аппаратуры, при использовании дизельного и биодизельного топлива в различных процентных соотношениях компонентов.

Research is aimed at solving practical problems with the possibility of substantiating and developing recommendations for the fuel used and its constituent components, in order to achieve the required characteristics of energy efficiency, at the stages of technological production and use in the operation of power plants of mining machines. The conducted studies of the processes and methods for increasing the energy efficiency of fuel conversion in power plants of mining machines, in conjunction with the study of environmental indicators, made it possible to establish a close relationship with the qualitative characteristics of the fuel used. The studies were carried out on an experimental complex consisting of a diesel power plant and calculation and recording equipment, using diesel and biodiesel fuel in various percentages of components.
STRUCTURAL, TECHNOLOGICAL AND OPERATIONAL IMPROVEMENT OF FOREIGN AUTOMOTIVE EQUIPMENT
Authors: Грушников Виктор Александрович
Published: July 2024

Безопасность широко использующегося на автомобильных дорогах общего пользования такого массового подвижного состава, как автомобильные колесные транспортные средства определяет его востребованность потребителями, а закладывается на стадиях проектирования, изготовления и эксплуатации. В этой взаимосвязанной конструкторско-технологической цепочке свойств и набора характеристических параметров все большее внимание уделяется их сквозному прослеживанию и все большую роль начинает играть цифровизация на всех без исключения стадиях создания и использования.

The safety of such mass rolling stock as automobile wheeled vehicles, which is widely used on public roads, determines its demand for consumers, and is laid down at the stages of design, manufacture and operation. In this interconnected design and technological chain of properties and a set of characteristic parameters, more and more attention is paid to their end-to-end traceability, and the digitalization of all stages of creation and use without exception begins to play an increasingly important role.
Existence of Large Sublattices Isomorphic to Boolean Algebra in a Candidate Lattice
Authors: Виноградов Д.В.
Published: July 2024

Вероятностный подход к извлечению знаний с помощью операции сходства возник как способ преодоления необходимости порождения (потенциально экспоненциальной) решетки всех кандидатов (например, для случая булевой алгебры). В настоящей работе доказано, что для случайной плотной обучающей выборки, порождаемой последовательностью Бернулли, вероятность того, что в решетке кандидатов возникнет большая подрешетка, изоморфная булевой алгебре, будет стремиться к единице при увеличении размера выборки.

Algebraic Machine Learning emerged as a way to overcome the need to generate a (potentially exponential) lattice of all candidates (for example, for the case of Boolean algebra). In this paper, it is proved that for a random training sample generated by the Bernoulli sequence, the probability that a large sublattice will arise in the lattice of candidates, isomorphic to Boolean algebra, will tend to unity as the sample size increases.
O MANEJO DA DIABETES GESTACIONAL: UMA REVISÃO NARRATIVA
Authors: Almeida Ludmila Lima De , Alves Aline Viana , Naves Isabela Cavalcante Pinto Lanzilote , Lima Luiza Helena Camacho , Freire Nicole Van Hemelryck Moniz
Published: July 2024

O diabetes mellitus gestacional (DMG) é uma complicação metabólica comum na gravidez, que exige identificação e manejo precoce para prevenir complicações. Este estudo revisa as abordagens diagnósticas, a prevalência, a prevenção e as intervenções no estilo de vida, o uso de biomarcadores moleculares e a eficácia do exercício físico no manejo do DMG. A revisão revela que, embora a prevalência do DMG esteja aumentando, principalmente devido à obesidade e ao sedentarismo, estratégias preventivas e intervenções no estilo de vida são essenciais para o manejo eficaz da condição. A pesquisa sobre biomarcadores moleculares oferece novas ferramentas para diagnóstico e monitoramento precoce, enquanto o exercício físico, apesar das variações nos resultados, é geralmente seguro e pode melhorar o controle glicêmico. Conclui-se que uma abordagem integrada é fundamental para melhorar os desfechos maternos e fetais.
Propriedades Biológicas e Impacto de Agregados Plaquetários na Implantodontia: Revisão de literatura
Authors: Oliveira Mariana Simões de , Gomes Taleessa Vieira , Oliveira William Simões de , Apolônio Ana Carolina Morais , Oliveira Raphael de Almeida
Published: July 2024

Esta revisão de literatura aborda as propriedades biológicas e o impacto dos agregados plaquetários na implantodontia. Através de uma análise de artigos publicados entre 1998 e 2024, selecionados nas bases de dados PubMed e Scopus, foram exploradas as aplicações clínicas desses biomateriais em enxertos ósseos, regeneração óssea guiada, levantamento de seio maxilar, implantes com carga imediata e tratamento da peri-implantite. Os agregados plaquetários têm mostrado ser eficazes na promoção da cicatrização e regeneração tecidual, melhorando a osseointegração e reduzindo a inflamação, devido à liberação de fatores de crescimento como PDGF, TGF-β, VEGF, IGF-1 e EGF. No entanto, a variabilidade na composição dos agregados e as diferenças nos protocolos de preparação representam desafios que necessitam de padronização para otimizar os efeitos clínicos. A integração contínua desses biomateriais na prática odontológica moderna promete não apenas melhorar os resultados clínicos, mas também aumentar a qualidade de vida dos pacientes, consolidando os agregados plaquetários como ferramentas essenciais na implantodontia.
FEATURES OF DESIGN AND CALCULATION OF TEMPERATURE-SHRINKAGE EXPANSION JOINTS OF BUILDINGS WITH STONE EXTERNAL WALLS
Authors: Шмелев Г.Д. , Кононова М.С. , Копытин А.А.
Published: July 2024

Проведен анализ действующих нормативно-технических документов, касающихся вопросов расчета и назначения длин участков между температурно-усадочными вертикальными деформационными швами каменной кладки наружных стен зданий. Выполнен обзор конструктивных особенностей деформационных швов в типовых проектах первых массовых серий. Обозначены критерии, на основании которых принимают максимальное расстояние между температурно-усадочными швами. Представлен анализ нормативных документов, регламентирующих проектирование деформационных швов. Показано, что нет единых рекомендаций по методикам их расчетов, что может привести к разрушению отдельных строительных конструкций в процессе эксплуатации. Приведены примеры строительных конструкций зданий, имеющих температурные деформации в виде трещин, вызванных нарушением работы температурно-усадочных швов. Выявлена тенденция образования преимущественно вертикальных трещин. Рассмотрены основные положения методики расчета температурных деформаций каменных стен, основанные на одновременном использовании нескольких нормативных документов. Показано, что расчеты, выполненные с использованием формул из различных документов, дают значительно расходящиеся результаты.

The article analyzes the current regulatory and technical documents concerning issues of calculating and assigning the lengths of sections of masonry on the outer walls of buildings between temperature-shrinkable vertical expansion joints. We reviewed the design features of expansion joints in standard designs of the first mass construction. We indicated some criteria on the basis of which the maximum distance between temperature-shrinkage expansion joints is accepted. We also analyzed regulatory documents governing the design of expansion joints. It is shown that there are no uniform recommendations on the methods of their calculations, which can lead to the destruction of individual building structures during operation. We present some examples of structures that have thermal deformations in the form of cracks caused by malfunction of temperature-shrinkage expansion joints. We revealed a tendency for the formation of predominantly vertical cracks. We as well considered the main provisions of the methodology for calculating temperature deformations of stone walls, based on the simultaneous use of several regulatory documents. It is shown that calculations performed using formulas from various documents give significantly divergent results.
ASSESSMENT OF THE FEASIBILITY OF USING SOLAR SYSTEMS IN THE CLIMATIC CONDITIONS OF THE CENTRAL CHERNOZEM REGION
Authors: Чудинов Д.М. , Петрикеева Н.А. , Попова Н.М.
Published: July 2024

Мини-гелиостанции достаточно эффективно применяются для генерации электроэнергии в частном секторе, промобъектах и небольших общественных объектах типа частных гостиниц. Целесообразность их использования обусловлена достаточным количеством солнечной радиации. В работе проанализирована стоимость солнечной установки горячего водоснабжения в исполнении подрядчика в текущем уровне цен и основные технико-экономические показатели аналогичных установок отечественных и зарубежных производителей. Рассмотрены четыре варианта гелиоустановок, три из которых широко известны и являются на данный момент наиболее конкурентоспособными. Представлены результаты расчета срока окупаемости, коэффициента замещения, стоимости данных установок в условиях Центрального Черноземья в зависимости от производителя. Показано, что целесообразность применения зависит от начальных капитальных вложений и варианта исполнения, причем важным показателем является стоимость обслуживания и возможность дублирования этих систем традиционным способом.

Mini-solar stations are used quite effectively to generate electricity in the areas of detached housing, industrial facilities and small public facilities such as private hotels. The feasibility of their use is determined by the sufficient amount of solar radiation. The work analyzes the cost of a solar hot water supply installation performed by a contractor at the current price level and the main technical and economic indicators of similar installations from domestic and foreign manufacturers. In this article we consider four options for solar power plants, three of which are widely known and are currently the most competitive. We also present the results of calculating the payback period, replacement rate, and cost of these installations in the conditions of the Central Chernozem Region, depending on the manufacturer. It is shown that the feasibility of application depends on the initial capital investment and design option, with an important indicator being the cost of maintenance and the possibility of duplicating these systems in the traditional way.
JUSTIFICATION OF THE NEED FOR ASSESSING THE ENVIRONMENTAL SAFETY OF FACILITIES OF MULTI-FUNCTIONAL ROAD SERVICE ZONES FOR TRANSPORT TOURISM
Authors: Яременко С.А. , Гармонов К.В. , Жерлыкина М.Н. , Макаров А.Р.
Published: July 2024

Проведен анализ развития внутреннего автотуризма, направленного на формирование комфортной развитой транспортной инфраструкты, в основу которой будут входить объекты дорожного сервиса исключительно в составе многофункциональных зон (МФЗ). Рассмотрены планировки новых и возводимых МФЗ, выявлены объекты, оказывающие неблагоприятное воздействие на окружающую среду, прилегающую территорию и здоровье человека. Представлен многокритериальный анализ факторов, влияющих на распространение вредных веществ от автозаправочных станций (АЗС) и позволяющий присвоить класс экологической безопасности АЗС. Обоснована необходимость оценки экологической безопасности отдельных объектов и в целом МФЗ дорожного сервиса транспортного туризма, а также разработки методики, позволяющей оценить уровень влияния МФЗ на окружающую среду и внедрить определенный перечень мероприятий по снижению его негативного воздействия.

We conducted the analysis of the development of domestic transport tourism aimed at the formation of a comfortable well-developed transport infrastructure, which will be based on road service facilities exclusively as part of multifunctional zones (MFZ). We reviewed the layout of the new MFZ and MFZ under construction, we as well identified facilities that have an adverse impact on the environment, the surrounding area and human health. In this article we present a multi-criteria analysis of the factors influencing the spread of harmful substances from gas stations which allows assigning an environmental safety class to gas stations. We substantiated the necessity of assessing the environmental safety of individual facilities and as a whole the MFZ of the road service of transport tourism. We also describe here the development of a methodology to assess the level of the MFZ's impact on the environment and implement a certain list of measures to reduce its negative impact.
ОСОБЕННОСТИ БИОЛОГИЧЕСКОЙ АКТИВНОСТИ ТЕХНОЛОГИЧЕСКОГО ГРУНТА, ПРОИЗВЕДЕННОГО ИЗ ОРГАНИЧЕСКИХ ОТХОДОВ
Authors: Ермолаева С.В. , Мадифурова Л.Ю. , Рахматулина Г.Э.
Published: July 2024

Потребность в разработке и реализации новых технологий обращения с отходами встала крайне остро и требует поиска путей решения. Одним из таких решений является промышленное компостирование, или биоферментация органической составляющей отходов с последующим получением нетрадиционных удобрений и технологических грунтов. Для исследований были взяты образцы технологического грунта с рекультивационной площадки полигона твердых бытовых отходов «Баратаевский». Технический грунт обладает биологической активностью, достаточной для стимуляции процессов восстановления нарушенных земель и для использования в качестве рекультиванта для полигонов ТКО.
НЕКОТОРЫЕ ОСОБЕННОСТИ МИКРОФЛОРЫ ПОЧВЫ
Authors: Турлова Ф.С. , Усаева Я.С. , Хадаева Р.
Published: July 2024

Микрофлора почвы всегда представляла большой интерес с точки зрения микробиологии. Его населяют большое количество простейших, микроскопических водорослей, грибов. Бактерии представляют наиболее значимую часть обитателей почвы. Это нитрифицирующие и азотфиксирующие бактерии, серобактерии, микрококки, клостридии и т.д. Все они играют большую роль в процессах почвообразования, очищения, круговорота веществ.
СИНТЕЗ ОКСИДНЫХ ВОЛЬФРАМОВЫХ БРОНЗ В ИОННЫХ РАСПЛАВАХ
Authors: Байсангурова А.А. , Гишкаева Ф.М. , Кулаева М.Х.
Published: July 2024

Методами ВПА, ДТА, РФА изучена двойная система вольфрамата и хлорида лития LiCI-LiWO4. Выявлено, что система LiCI - Li2WO4 имеет эвтектический и перетектический составы с координатами 76,5% LiCI, 23,5% Li2WO4 и 523 оС, и двойной перитектической точкой (Р) между соединением LiCI . 2Li2WO4 и Li2WO4 с координатами: 33LiCI, 67% Li2WO4 и 560 оС.
ПРЕИМУЩЕСТВА ДВУЯЗЫЧНОГО ОБРАЗОВАНИЯ
Authors: Гаургаева А.Т.
Published: July 2024

Данное исследование направлено на обобщение и проведение выводов по актуальности и важности знания нескольких языков. В исследовании рассказывается про преимущества двуязычного образования. Актуальность данной работы заключается в том, что двуязычное образование становится все более популярным в современном образовательном пространстве. Отмечается, что дети, проходящие двуязычное обучение, имеют преимущества в умственном развитии, межкультурном понимании и более высокой адаптивности к меняющемуся миру.
Цель данной работы заключается в изучении преимуществ двуязычного образования и его влияния на развитие детей. В результате проведенного исследования будет рассмотрено влияние двуязычного обучения на когнитивные процессы, академические успехи и перспективы детей, а также будут выявлены факторы, которые могут повлиять на успешное внедрение данной системы образования.
ПЛАНИРОВАНИЕ СОВРЕМЕННОГО УРОКА НЕМЕЦКОГО ЯЗЫКА
Authors: Саламова М.В. , Махашева Д.Р.
Published: July 2024

В статье рассматриваются методики и приемы планирования современного урока немецкого языка. Автор рассматривает общие и частичные цели обучения.
ВЛИЯНИЕ НОВЫХ ТЕХНОЛОГИЙ НА РАЗВИТИЕ ЯЗЫКА И КОММУНИКАЦИИ
Authors: Шахбулатова Д.Г.
Published: July 2024

Данная статья посвящена исследованию актуальных проблем влияния современных технологий на развитие языка и коммуникации. Автор рассматривает современные методы коммуникации между людьми в интернет платформах, исследует влияние социальных сетей на языковые нормы общения. В статье анализируется использование различных видов акронимов, эмотиконов и мемов в процессе общения через социальные сети. Также рассматривается то, как интернет приложения помогаю при изучении иностранного языка.
Perineural invasion in prostate cancer is associated with Schwann cells and disruption of circadian rhythm-related gene expression: A bioinformatics approach
Authors: Lopes Silva Sérgio , de Omena Neta Genilda Castro , Lima Rocha Rodger Marcel , da Silva Fernandes Duarte Ana Kelly , de Carvalho Fraga Carlos Alberto
Published: July 2024

Schwann cells in the tumor microenvironment are reportedly involved in the production of several factors that benefit cancer cell growth. During this process, Schwann cells are dedifferentiated and facilitate cancer cellular proliferation. The cells then migrate to the region close to the tumor tissue and assist the development of the neoplastic cells. Accordingly, the present study was designed to evaluate the perineural invasion in prostate cancer, in association with disrupted circadian rhythm-related gene expression in Schwann cells. Initially, we identified a database reporting gene expression in Schwann cells in a neoplastic context from the GEO Datasets platform in the GEO repository. The database contains the expression results from experiments in which two factors produced by tumor cells were added to cell cultures. Comparisons were made between samples from the first and third passages. Then, these data were used in differential gene expression analysis and combined with differential expression data of genes upregulated in perineural invasion-negative and -positive prostate cancers. We observed that the “axon guidance” pathway was upregulated in perineural invasion-negative prostate cancers. Meanwhile, upregulated mRNAs activated the “axon guidance” pathway and, together with ROBO1 and MPZ upregulation, inhibited perineural invasion pathways. Both genes are also associated with inhibition of Schwann cell migration. PER3, NR3C1, PPARGC1A, TIMP3, ID2, PDE6B, and CAVIN1 were upregulated in perineural invasion-negative tumors, while SLC25A10 was upregulated. We also observed upregulated expression in perineural invasion-positive tumors for genes such as PPARGC1A, TIMP3, S100A8, ID2, DEFB1, AQP3, ASS1, PDE6B, NEFH, and CAVIN1. AQP3 and NEFH were upregulated only in perineural invasion-positive tumors and PER3 and NR3C1 were upregulated only in perineural invasion-negative samples. The findings revealed that circadian rhythm and/or melatonin disruption are associated with dedifferentiation of Schwann cells, which consequently produce a set of factors that drive tumor progression. These processes may also be involved in tumor invasion into the perineural tissue in prostate cancer.
Gender disparities in telehealth use among older adults in the United States during the COVID-19 pandemic
Authors: Summer Chen Xiayu , Wang Kun
Published: July 2024

The coronavirus disease 19 (COVID-19) pandemic underscored the significance of telehealth as a health-care delivery method, particularly for the vulnerable older adult population. Nonetheless, disparities in accessing and utilizing telehealth services persist, influenced by demographic and socioeconomic factors such as gender. This study aims to investigate the utilization of telehealth services among older adults in the United States, focusing on gender-related disparities and associated factors. Using the Round 10 and COVID-19 supplement data from the National Health and Aging Trends Study, the study examined 3,257 participants (male: 42.06%; female: 57.94%). We compared the use of telehealth services before and during the pandemic and conducted a series of logistic regression models to assess factors linked to telehealth utilization by gender. Overall, there was a significant shift toward greater use of telehealth among females during the pandemic, with multimorbidity significantly influencing the relationship between gender and telehealth utilization. For males, those who had multimorbidity (odds ratio [OR] = 2.03; 95% confidence interval [CI] = 1.07 – 3.84), owned a tablet before COVID-19 (OR = 1.89; 95% CI = 1.13 – 3.14), and learned new technologies during the pandemic (OR = 2.29; 95% CI = 1.37 – 3.82) had higher odds of telehealth use. For females, those with worse self-reported health scores (OR = 1.28; 95% CI = 1.03 – 1.59), owned a tablet (OR = 2.07; 95% CI = 1.32 – 3.23), and learned new technology (OR = 3.37; 95% CI = 2.17 – 5.24) during the pandemic demonstrated increased odds of telehealth use. Gender-based differences in telehealth utilization were evident, highlighting the need for targeted interventions that enhance older adults’ access to telehealth services and mitigate digital disparities.
RESEARCH ON THE APPLICATION OF ROTARY COMPRESSORS IN GAS TRANSMISSION SYSTEMS
Authors: Shikar Mammadov, Aghakishi Mammadov Shikar Mammadov, Aghakishi Mammadov
Published: July 2024

The article provides an analysis of the operating conditions of compressors used for gas transportation in the Azerbaijani gas industry and explores ways to effectively utilize them. It discusses primarily the types, technical specifications, constructions, and application areas of rotary compressors employed in the gas industry. Additionally, information is provided about various types of rotary compressors, including rotary-vane, screw, twin-screw, and scroll compressors.
Keywords: gas, vane, screw, rotor, scroll, compressor, cylinder, pressure, piston.
PROCESSING THE GUARANTEE OF ONLINE PARKING RESERVATION PROGRAM
Authors: Ruslan Aghakishiyev, Nazila Ragimova Ruslan Aghakishiyev, Nazila Ragimova
Published: July 2024

This article discusses the analysis and resolution of structured and unstructured problems in the field of transportation, the use of artificial intelligence and technological capabilities, and research in various fields related to transportation research, such as hybrid data sets, neurology, deep learning, and object recognition. In addition to this, the analysis of current issues and their adaptation in terms of time and financial benefits in almost all areas has been applied in the analysis of the Ministry of Transport.
Keywords: Deep Learning, Neural Network, Machine Learning, Object Recognition, Python, Yolo, YoloV3.
NON-DESTRUCTİVE TESTİNG (NDT) APPLİCATİONS İN ENSURİNG THE RELİABİLİTY AND SAFETY OF MEDİCAL EQUİPMENT: A COMPREHENSİVE REVİEW
Authors: Kamran Aliyev Kamran Aliyev
Published: July 2024

The increasing complexity and criticality of medical equipment in healthcare settings demand rigorous testing methodologies to ensure their reliability and safety. This paper explores the diverse applications of Non-Destructive Testing (NDT) in the realm of medical equipment testing. NDT techniques, traditionally employed in industries such as aerospace and manufacturing, offer unique advantages for assessing the structural integrity, functionality, and performance of medical devices without causing harm. The paper begins by providing an overview of NDT principles and methodologies, highlighting their non-invasive nature and ability to detect flaws and defects at an early stage. Subsequently, it delves into the specific NDT techniques applicable to medical equipment, including ultrasound, radiography, magnetic particle testing, and eddy current testing. Each technique's principles, advantages, and limitations are discussed in the context of medical device testing. Furthermore, the paper reviews real-world case studies and examples where NDT has been successfully applied to assess the quality and reliability of various medical equipment, ranging from imaging devices to surgical instruments. The challenges and potential limitations of implementing NDT in the medical field are also addressed, along with suggestions for overcoming these obstacles. In conclusion, this comprehensive review emphasizes the pivotal role of NDT in ensuring the integrity and safety of medical equipment. By leveraging NDT techniques, healthcare professionals can enhance the quality assurance processes, minimize the risk of equipment failure, and ultimately contribute to the improvement of patient outcomes. This paper aims to serve as a valuable resource for researchers, practitioners, and stakeholders in the healthcare and NDT communities, fostering a deeper understanding of the synergies between these two critical domains.
Keywords: Non-Destructive Testing (NDT), Medical Equipment, Reliability, Safety, Quality Assurance.
INNOVATIONS IN MODERN EDUCATION, THEIR APPLICATION TRENDS AS ONE OF THE MAIN ISSUES IN PEDAGOGY
Authors: Tunzala Amiraslanova, Turana Misirli Tunzala Amiraslanova, Turana Misirli , Roya Ismayilova Roya Ismayilova
Published: July 2024

The main aim of the article is to research the essence of the concept of "innovation in education", the main approaches to the development of innovation processes in education. Thus, types of innovations in education, stages of their introduction and realization, their influence on teaching and learning methods and thinking styles of teachers and students, their role in improving the quality of education, training of teaching staff with high level, excellent knowledge, advantages of training based on innovative methods over traditional training are revealed.
Relevance of the article. Innovations applied in education, their types, methods and methods, solutions to the problems encountered in the fields of application, researching the impact of innovation on the development of the education organization and quality control system are extremely important and seriously needed issues in the current period. To sump up, from this point of view, the article is relevant and actual.
Scientific novelty of the article. The article researches the issues rrgarding innovative education and teaching, the types of innovations, the stages of implementation, the successful results achieved in innovative education, ways to improve the quality of teaching, and ways to increase the effectiveness of learning and teaching.
Practical importance of the article. The kinds of innovation mentioned in the article, the analysis and research of their application methods can be used in predicting and evaluating the quality of education, and at the same time, they can be a guiding source for the activities of those involved in education policy.
Keywords: education, teaching, innovation, innovative education, innovative teaching, innovative methods, information and communication technology tools, student, teacher, learning, teaching
EU Competition Law, Fundamental Rights and the Principle of Transparency – An Evolving Relationship
Authors: Teleki Cristina
Published: July 2024

Faced with the challenges posed by gatekeepers, EU competition law is undergoing a period of significant change. I attempt to show in this article that one can understand this change as a shift in the relationship between EU competition law and fundamental rights. More precisely, I show that the initial relationship between these two factors has been operational, in the sense that fundamental rights have been relied upon to operationalize the substance of competition law. In the operational relationship, the right to a fair trial has been deployed by the European Commission to create and expand its quasi-judicial arm. This long-standing operational relationship has recently evolved into an informative one, where the rights to privacy and data protection have informed the European Commission’s merger assessments involving gatekeepers. Finally, I argue that, in light of the Meta/Facebook case and recent EU legislation, the relationship between EU competition law and fundamental rights can be called foundational. Indeed, it appears that both the CJEU and EU legislators intend to inject fundamental rights into the foundations of EU competition law. I also highlight how the principle of transparency has played an important role in these developments as an enabler and magnifier. These changes are significant and will impact the work of competition authorities, data protection authorities and other public bodies in the EU.
The Legal Professional Privilege in Competition Law Cases – A Key Element in Protecting the Proper Administration of Justice
Authors: Andersson Helene
Published: July 2024

The legal professional privilege is an important principle underpinning the EU judicial system as it ensures the proper administration of justice, procedural efficiency and protects fundamental rights such as a client’s defence rights and the right to privacy enshrined in Articles 47 and 7 of the Charter. In competition cases, the European Commission has relied on an old ruling from the Court of Justice of the European Union (the ECJ), and only acknowledged one of these aims – the protection of the client’s defence rights. While the ECJ has recently received the chance to align the EU standard to that of the ECHR by broadening the scope of protection, the Commission appears unwilling to abandon its previous stance. It is important that the Commission shoulders the responsibility to ensure a procedure that is fair, and which acknowledges the basic principles underpinning a society governed by the rule of law. The current approach breathes life into questions on the legitimacy of its actions and the appropriateness of letting it take on the roles of enforcer, prosecutor and judge in competition cases, where companies not only risk having to pay fines of up to ten percent of their annual turnover, but now also appear to have to face the threat of divestitures should the Commission find that they are infringing the EU competition rules.
Multi-objective faculty course assignment problem based on the double parametric form of fuzzy preferences
Authors: Bhoi Sunil B. , Dhodiya Jayesh M.
Published: July 2024

This paper presents a mathematical model of the multi-objective faculty course assignment problem based on the double parametric form of fuzzy preferences. The fuzzy preferences are based on an analysis of faculty feedback given by students and an analysis of the results of the previous year’s examination of students. The proposed model is developed utilizing faculty members’ preferences, the preferences of an administrator for faculty members to courses, and fuzzy preferences based on faculty feedback and student result analysis. The double parametric approach solves a timetabling problem based on information from a university’s hypothetical numerical data. The fuzzy programming technique with linear membership function is applied to generate efficient and non-dominated allocations with better optimal values and degree of satisfaction of objective functions for different values of parameters α and β for fuzzy preferences. Results are found using LINGO19.0 software.
Evaluation and choice of an anti-aircraft missile system under uncertain conditions based on fuzzy-integral calculus and hierarchical cluster analysis
Authors: Sveshnikov Sergey , Bocharnikov Victor , Mudrak Yuri
Published: July 2024

Evaluation and choice of anti-aircraft missile weapon systems (AAMWSs) are a relevant problem in many countries. Estimates are often reduced to one top-level criterion. This is questionable since subordinated criteria are usually difficult to compare and decision-makers excluded from the final decision. The solution to the problem should also take into account non-statistical uncertainty. We propose to use a combination of two algorithms. The first algorithm calculates the estimates of AAMWSs in the criteria hierarchy using fuzzy-integral calculus. The hierarchy relates the characteristics of the AAMWSs to the three top-level criteria. In the space of these criteria, the second algorithm based on hierarchical clustering forms a class of the best AAMWSs equivalent to each other. The decision-maker makes the final choice from the obtained class, taking into account non-formalized factors. These algorithms are tested using the example of medium-range AAMWSs.
A steepest feasible direction method for linear programming. Derivation and embedding in the simplex method
Authors: Wolde Biressaw C. , Larsson Torbjörn
Published: July 2024

A feasible direction method for linear programming has been proposed. The method is embedded in the framework of the simplex method, even though it works with non-edge feasible directions. The direction used is the steepest in the space of all variables or an approximation thereof, and it is found by solving a strictly convex quadratic program in the space of the nonbasic variables. Further, this program guarantees the feasibility of the direction even in the case of degeneracy. To remain within the simplex framework, the direction is represented by an auxiliary, or external, nonbasic column, which is a nonnegative linear combination of original nonbasic columns. We have made an experimental evaluation of the suggested method on both nondegenerate and highly degenerate problem instances. The overall results are very promising for continued research along this line, especially concerning various computational strategies that can be applied when the method is implemented.
Kentsel Direnci Kadın Hakları Bağlamında Düşünmek: Avrupa Birliği ve Türkiye Üzerine Bir İnceleme
Authors: Kutlu Salih Ziya , Saygın Didem , Erdem Asime Dilara
Published: July 2024

Literatürde kentsel direnç ya da kentsel dayanıklılık olarak yer alan kavram; genellikle iklim değişikliği ya da doğal afetler alanında düşünülse de aslında ekonomik, sosyal ve kültürel boyutları da vardır. Bu nedenle kenti bütün olarak düşünmek ve kentin içinde yaşayan insanların sosyal ve ekonomik durumlarını, hayat kalitelerini, mekânsal alanlarını kentsel direnç bağlamında da ele almak gerekmektedir. Kentsel direncin sosyal risklerden ayrı tutulamayacağı göz önünde bulundurularak kentlerde yaşayan dezavantajlı grupların kentin yaşadığı şoklardan daha fazla etkilendiği vurgulanmaktadır. Toplumun yarısını oluşturan kadınların ise kentsel şokları ve kentsel yoksulluğu daha fazla hissettikleri düşünülmektedir. Bu nedenle araştırmanın sorusu kadınların ekonomik hayata katılımlarının artması kentsel dirençliliklerini arttırır mı? olarak belirlenmiştir. Kentsel risklerden en az hasarla kurtulabilmek için kadınların eğitim düzeylerinin yükselmesi, istihdamlarının arttırılması gerekmektedir. Bu kapsamda EUROSTAT verileri ile AB’de; TÜİK verileri ile Türkiye’de kadının konumu ve kentsel direnç oluşturabilme imkânı değerlendirilmiştir. Bu değerlendirme yapılırken ekonomik, eğitim ve güvenlik temaları seçilmiş ve bu temalardaki veriler incelenmiştir. Verilerden elde edilen bulgularla kadınların kentsel şoklardan daha az etkilenmeleri için konumlarının güçlendirilmesi gerektiği sonucuna ulaşılmıştır.
Prothrombin Complex Concentrate as a Key Adjunct in Massive Hemorrhage Management in Placenta Accreta Spectrum Disorder: A Case Report
Authors: Pramana Putu Bagus Gin Gin , Tjokorda Gde Agung Senapathi  , Pontisomaya Parami  , Tjahya Aryasa
Published: July 2024

Placenta accreta spectrum disorder (PASD) is a severe obstetric complication associated with significant hemorrhage risk. This report highlights the successful use of prothrombin complex concentrate (PCC) as part of a multidisciplinary approach to managing a case of massive hemorrhage in PASD. A 36-year-old woman, G3P2002, at 33 weeks gestation, diagnosed with placenta previa totalis and suspected PASD, underwent a planned cesarean hysterectomy. The surgery was complicated by 5200 mL hemorrhage due to placental invasion and bladder injury. Hemodynamic instability was managed with massive transfusion protocol activation, including PCC, tranexamic acid, and packed red blood cells. Intra-abdominal packing was performed for hemostasis, and the bladder injury was repaired. Continued PCC administration in the ICU, along with other supportive measures, resulted in hemorrhage control and stabilization. The patient was successfully extubated and discharged after a second surgery to remove packing. This case emphasizes the vital role of PCC in the multidisciplinary management of massive hemorrhage in PASD. Early recognition of PASD risk factors and prompt intervention, including PCC administration, are crucial for optimal maternal outcomes.
The Role of NT-proBNP in the Diagnosis of Peripartum Cardiomyopathy with Multiple Left Ventricular Thrombus: A Case Report
Authors: Yashinta Octavian Gita Setyanda  , Yaswir Rismawati
Published: July 2024

Background: Peripartum cardiomyopathy (PPCM) is a rare but serious condition characterized by left ventricular dysfunction in late pregnancy or early postpartum. Early diagnosis is essential to prevent complications such as thromboembolism. N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a promising biomarker for the diagnosis of PPCM.
Case presentation: An 18-year-old female presented with progressive shortness of breath and generalized edema. Physical examination and echocardiography revealed acute heart failure with multiple left ventricular thrombus. Very high levels of NT-proBNP (1,796 pg/mL) supported the diagnosis of PPCM. The patient was successfully treated with standard heart failure therapy and anticoagulants.
Conclusion: This case report highlights the importance of NT-proBNP in the early diagnosis of PPCM and detecting of thromboembolic complications. Significant increases in NT-proBNP levels, even without obvious symptoms, should be promptly evaluated for PPCM, especially in high-risk populations.