bluuebunny/crossref_metadata_2025 huggingface dataset:
Fair and Efficient Memory Sharing: Confronting Free Riders
Authors: Friedman Eric J. , Gkatzelis Vasilis , Psomas Christos-Alexandros , Shenker Scott
Published: September 2019

A cache memory unit needs to be shared among n strategic agents. Each agent has different preferences over the files to be brought into memory. The goal is to design a mechanism that elicits these preferences in a truthful manner and outputs a fair and efficient memory allocation. A trivially truthful and fair solution would isolate each agent to a 1/n fraction of the memory. However, this could be very inefficient if the agents have similar preferences and, thus, there is room for cooperation. On the other hand, if the agents are not isolated, unless the mechanism is carefully designed, they have incentives to misreport their preferences and free ride on the files that others bring into memory. In this paper we explore the power and limitations of truthful mechanisms in this setting. We demonstrate that mechanisms blocking agents from accessing parts of the memory can achieve improved efficiency guarantees, despite the inherent inefficiencies of blocking.
Pareto Efficient Auctions with Interest Rates
Authors: Goel Gagan , Mirrokni Vahab , Leme Renato Paes
Published: September 2019

We consider auction settings in which agents have limited access to monetary resources but are able to make payments larger than their available resources by taking loans with a certain interest rate. This setting is a strict generalization of budget constrained utility functions (which corresponds to infinite interest rates). Our main result is an incentive compatible and Pareto-efficient auction for a divisible multi-unit setting with 2 players who are able to borrow money with the same interest rate. The auction is an ascending price clock auction that bears some similarities to the clinching auction but at the same time is a considerable departure from this framework: allocated goods can be de-allocated in future and given to other agents and prices for previously allocated goods can be raised.
Impact of Older Age and Comorbidity on Locoregional and Distant Breast Cancer Recurrence: A Large Population-Based Study
Authors: de Boer Anna Z. , van der Hulst Heleen C. , de Glas Nienke A. , Marang-van de Mheen Perla J. , Siesling Sabine , de Munck Linda , de Ligt Kelly M. , Portielje Johanneke E. A. , Bastiaannet Esther , Liefers Gerrit Jan
Published: September 2019

Background

Studies have demonstrated worse breast cancer-specific mortality with older age, despite an increasing risk of dying from other causes due to comorbidity (competing mortality). However, findings on the association between older age and recurrence risk are inconsistent. The aim of this study was to assess incidences of locoregional and distant recurrence by age, taking competing mortality into account.

Materials and Methods

Patients surgically treated for nonmetastasized breast cancer between 2003 and 2009 were selected from The Netherlands Cancer Registry. Cumulative incidences of recurrence were calculated considering death without distant recurrence as competing event. Fine and Gray analyses were performed to characterize the impact of age (70–74 [reference group], 75–79, and ≥80 years) on recurrence risk.

Results

A total of 18,419 patients were included. Nine-year cumulative incidences of locoregional recurrence were 2.5%, 3.1%, and 2.9% in patients aged 70–74, 75–79, and ≥80 years, and 9-year cumulative incidences of distant recurrence were 10.9%, 15.9%, and 12.7%, respectively. After adjustment for tumor and treatment characteristics, age was not associated with locoregional recurrence risk. For distant recurrence, patients aged 75–79 years remained at higher risk after adjustment for tumor and treatment characteristics (75–79 years subdistribution hazard ratio [sHR], 1.25; 95% confidence interval [CI], 1.11–1.41; ≥80 years sHR, 1.03; 95% CI, 0.91–1.17).

Conclusion

Patients aged 75–79 years had a higher risk of distant recurrence than patients aged 70–74 years, despite the higher competing mortality. Individualizing treatment by using prediction tools that include competing mortality could improve outcome for older patients with breast cancer.
Synthesis of organic-inorganic hybrid nanoflowers using Trigonella foenum-graecum seed extract and investigation of their anti-microbial activity
Authors: ALTINKAYNAK Cevahir , ILDIZ Nilay , BALDEMİR Ayşe , ÖZDEMİR Nalan , YILMAZ Vedat , ÖÇSOY İsmail
Published: September 2019

Herein
we report a green method for the synthesis of organic-inorganic hybrid
nanoflowers using a Trigonella
foenum-graecum L. (TF) (Fenugreek seeds) extracts as an organic part and
copper ions acting as an inorganic part. The organic-inorganic hybrid
nanoflowers using TF seed extract (TF-Cu2+ hNFs) were characterized
by SEM, XRD, EDX and FTIR. The morphology of the TF-Cu2+ hNFs was
quite spherical and monodisperse with ∼18μm size. The TF-Cu2+
hNF exhibited the effective anti-bacterial activity against Enterococcus
faecium, Enterococcus faecalis, Staphylococcus aureus, Bacillus cereus,
Salmonella typhi and Escherichia coli at 1-10 µg ml-1
concentrations except against Pseudomonas aeruginosa and Haemophilus
influenza. However, both TF-Cu2+ hNFs and free TF extracts
showed any antifungal activities against Candida albicans or Candida
glabrata. The study revealed that TF-Cu2+ hNFs could be used as
a therapeutic agent for microbial infections and has the potential to overcome
drug resistance.
MojoSort™ Human CD14 Nanobeads Column Protocol v1
Authors: Li Sam
Published: September 2019

BioLegend MojoSort™ nanobeads work in commonly used separation columns, based on our internal research as well as validation by external testing by academic labs. This simple protocol consists of following the MojoSort™ protocol to label the cells with pre-diluted MojoSort™ reagents and using the columns as indicated by the manufacturer. Note: Due to the properties of our beads, it may be possible to use far fewer beads than with other commercial suppliers. We recommend a titration to find the best dilution factor. However, as a general rule, dilutions ranging from 1:3 to 1:20 for the Nanobeads can be used. Please contact BioLegend Technical Service (tech@biolegend.com) if further assistance is needed.
MojoSort™ Isolation Kits Column Protocol - 1 v1
Authors: Li Sam
Published: September 2019

BioLegend MojoSort™ nanobeads work in commonly used separation columns, based on our internal research as well as validation by external testing by academic labs. This simple protocol consists of following the MojoSort™ protocol to label the cells with pre-diluted MojoSort™ reagents and using the columns as indicated by the manufacturer. Note: Due to the properties of our beads, it may be possible to use far fewer beads and less antibody cocktail that with other commercial suppliers. We recommend a titration to find the best dilution factor. However, as a general rule, dilutions ranging from 1:2 to 1:10 for the antibody cocktail can be used. Dilutions ranging from 1:5 to 1:20 for the Streptavidin Nanobeads can be used. Please contact BioLegend Technical Service (tech@biolegend.com) if further assistance is needed.
Self-Compassion Profile in Lampung Culture Perspective
Authors: Adiputra Sofwan
Published: September 2019

The aim of this research is to conduct a descriptive study about self-compassion profile of Lampung students based onupon the sequence of tribe and sex in STKIP Muhammadiyah Pringsewu Lampung. This research describes the difference of self-compassion level of students based on the tribe in Lampung, and the level of self-compassion based on gender. Self-compassion is the ability to be compassionate to yourself, entertain themselves and care when self-suffering, failures and imperfections. The results from this study explain that women have a lower level of self-compassion than men. In addition, the cultural factors in the students in Lampung do not have a big impact on self-compassion. This is because the people of Lampung who have open characteristics to mingle with other tribes. Self-compassion is expected to become a multicultural competency of a counselor because someone who has a high self-compassion will have the ability to care about the difficulties of others.
The Meaningfulness of Life in Multiethnic Perspective as the Foundation for Personal Guidance
Authors: Batubara Juliana
Published: September 2019

This study aims to describe the meaningfulness of life in a multi-ethnic perspective in the Guidance and Counseling (BK) program, Postgraduate School of Universitas Pendidikan Indonesia (UPI). The scope of this study is the understanding of self, the meaning of life, changing attitudes, self-attachment, directed activities and social support. Data about the meaningfulness of life is obtained by using a questionnaire instrument that has been prepared by the author and disseminated to postgraduate students of BK UPI. The results of this study aims to recognize the student's self potential, so it can be directed to a more positive and become the foundation in personal guidance.
DISCAPACIDAD Y PRISIÓN. Una reflexión en torno a la privación de libertad en personas con discapacidad intelectual
Authors: SÁNCHEZ MIRANDA María del Carmen , BAYONA JUAN María del Pilar
Published: September 2019

La presente revisión pretende realizar un acercamiento a la realidad en la que se encuentran las personas que sufren alguna discapacidad intelectual y que están privadas de libertad en los centros penitenciarios españoles. Se analizarán los factores que las vinculan al delito, se diferenciarán las medidas privativas y no privativas de libertad que se le ofrecen a este colectivo, así como se repasarán los recursos y las políticas sociales existentes tanto desde la administración penitenciaria como desde el tercer sector, así como los protocolos de atención a seguir para atender las necesidades de las personas con discapacidad intelectual que se encuentran inmersas en un proceso delictivo y en situación de internamiento. El objetivo final de esta reflexión es la obtención una serie de conclusiones sobre la cuestión de la discapacidad intelectual en prisión y establecer puntos de partida para una intervención socioeducativa adaptada al grupo estudiado.
Tax Arbitration Through Offshore Centres and Tax Havens
Authors: Dirva A. , Dirva C.
Published: September 2019

The aim of the study is to capture the most relevant aspects regarding the functioning of offshore centres and tax havens, focusing in particular on the most important conceptual and instrumental clarifications. There are several angles to approach the phenomenon of tax evasion that are pointed out in this article, alongside a comparison of various analytical perspectives and, based on these, a number of judgments regarding their (in)opportunity are issued. In order to make a consistent description of the tax havens, it is necessary to clarify the fundamentals, the specific determinants and the factors without which these structures could not exist in the first place, the main hypothesis being that the boundary between tax arbitration and tax evasion is highly ambiguous and this is the major rationale why polemics on this topic arise. The goal is to present as objectively as possible these offshore centres and tax havens activities, which are paramount financial centres, irrespective of the criticism made by those who deem them unfair, immoral or even evil, as well as dangerous. This article focuses on tax planning and tax arbitration practices (e.g., “treaty shopping”), concluding with a collection of rationales for a balanced view on fiscal competition.
ANALYSIS OF APPROACHES TO THE DESCRIPTION OF THE DEVELOPMENT PROCESSES OF MODERN MANAGEMENT
Authors: Tebekin A. V. , Egorovа A. A.
Published: September 2019

Phase, milestone and proposed combined (conceptual-phase) approaches to describing the development processes of modern management are considered. It is shown that the conceptual-phase approach to describing the development processes of modern management is the most promising, since it reflects the evolution of modern management development concepts that change according to the spiral law within the dynamics of technological patterns and allows forecasting the development prospects of management concepts.
Çocuklardaki çölyak hastalığının annelerin yaşam kalitesi ve depresyon düzeylerine etkisi
Authors: SEVİNÇ Nergiz , ÖZTÜRK Ahmet , SEVİNÇ Eylem
Published: September 2019

Giriş ve Amaç: Çölyak hastalığı olan çocukların sürekli olarak glutensiz diyete uyma zorunluluğu çocukla birlikte ailesine de psikososyal bir yük getirmekte ve özellikle çocuğun birincil bakımından sorumlu annelerin yaşam kalitesini ve psikososyal durumlarını olumsuz etkileyebilmektedir. Bu çalışmada çölyak hastalığı olan çocukların annelerinin, kontrol grubundaki çocukların anneleri ile karşılaştırılarak, yaşam kalitesinin ve depresyon düzeylerinin incelenmesi amaçlanmıştır.Gereç ve Yöntem: Çalışma Erciyes Üniversitesi Çocuk Sağlığı ve Hastalıkları Anabilim Dalı Gastroenteroloji Polikliniğinde 1 Temmuz-31 Aralık 2015 tarihleri arasında yapılmıştır. Çalışma grubuna; 93 çölyak hastalığı olan çocuğun annesi ile 93 sağlam çocuğun annesi olmak üzere toplam 186 anne alınmıştır. Çalışmaya katılan tüm annelerden sözlü onam alınarak, sosyodemografik veri formu, yaşam kalitesi ölçeği (SF-36) ve Beck Depresyon Ölçeği yüz yüze görüşme tekniği ile uygulanmıştır. Verilerin değerlendirilmesinde SPSS paket programı kullanılmıştır. İstatistiksel analizlerde p<0.05 değerleri anlamlı kabul edilmiştir.Bulgular: Çölyak hastalığı olan çocukların annelerinde kontrol grubundaki çocukların annelerine göre yaşam kalitesi puanları daha düşük bulunmuştur (Sırasıyla genel sağlık (32 ve 44), fiziksel fonksiyonellik (50 ve 80), fiziksel rol güçlüğü (50 ve 100), mental sağlık (48 ve 72), enerji (35 ve 60), emosyonel sağlık (33.33 ve 100), bedensel ağrı (30 ve 70) ve sosyal fonksiyonellik (50 ve 62.50). Özellikle eğitim düzeyi düşük olan, 4 ve üzeri çocuk sahibi olan, ekonomik durumu kötü olan ve herhangi bir işte çalışmayan çölyaklı çocuk annelerinde yaşam kalitesi puanları daha düşük bulunmuştur. Beck Depresyon Ölçeğine göre yapılan değerlendirmelerde de; çölyaklı çocuk annelerinde depresif belirti görülme oranı (%69.9) kontrol grubundaki annelere göre (%14.0) anlamlı derecede yüksek bulunmuştur. Yapılan ileri analizlerde; 41 yaş ve üzerinde olan, 4 ve üzeri çocuk sahibi olan, ekonomik durumu kötü olan ve köy ve kasabalarda yaşayan annelerde depresif belirti oranları daha fazla bulunmuştur. Sonuç: Annelerin, kronik hastalığı olan çocuğu ile uğraşırken yaşam kalitelerinin ve beden-ruh sağlıklarının olumsuz yönde etkilendiği tespit edilmiştir. Çölyak hastalığı olan bir çocuk tespit edildiğinde, annelerinin de yaşam kalitelerinin korunması ya da ruhsal sıkıntılarla karşılaşmalarının önlenmesi açısından takip edilmesinin ve destek olunmasının yararlı olacağı düşünülmektedir.
Cincuenta ediciones, veintiún años de existencia y persistencia en las investigaciones en derecho y ciencias sociales, su divulgación e impacto social
Authors: Matias Camargo Sergio Roberto
Published: September 2019

La revista Diálogos Saberes, Investigaciones en derecho y ciencias sociales, es la publicación seriada oficial del Centro de Investigaciones Socio Jurídicas de la Facultad de Derecho de la Universidad Libre de Bogotá, Sede Principal. Con el presente número, hemos publicado cincuenta ediciones ininterrumpidamente, en periodos semestrales.

Cumplimos veintiún años de existencia desde el lanzamiento del Número 1 el 25 de febrero de 1998 y catorce de reconocimiento por Colciencias como Revista Nacional Especializada de Carácter Científico e incluida en el Indice Bibliográfico Nacional-Publindex (indexada) en la Categoría C, desde el primer semestre de 2005, hasta el treinta de diciembre de 2019. Actualmente, se encuentra reconocida e incluida en los Servicios de Indexación y Resumen (Sires) con Comités de selección de Latindex (UNAM, México), Ebsco Academic Search Complete, The Left Index, Academic Search Ultimate, Fuente Académica plus y alojada en las bases de datos de Dialnet (Universidad de la Rioja, España).
Protection of client and consumer of financial services in European Union and Polish law
Authors: Magoń Karol
Published: September 2019

O artigo apresenta os principais pressupostos da Lei sobre o processamento de reclamações por participantes do mercado financeiro, bem como o Comissário Financeiro (Journal of Laws de 2016, item 892), sobre os meios de proteção dos clientes de serviços financeiros. Na primeira parte, o autor analisa as circunstâncias da entrada em vigor da lei. Em seguida, realiza uma comparação da Lei aos atos normativos que regulam a matéria analisada antes da entrada em vigor da lei. No final, o autor avalia o escopo, importância e natureza jurídica das soluções introduzidas na Lei para proteger os interesses dos clientes de serviços financeiros.
Technology trends, Education 4.0 and beyond
Authors: Keser Hafize , Semerci Ali
Published: September 2019

The real-time communication and collaboration of the internet of things, the internet of services and cyber-physical systems with each other and with people has started a new era in industrial production. This era called Industry 4.0, brought about revolutionary changes in many areas of life, including education. In order to fully exploit the potential of smart products, services and business opportunities that are expected to be widely used in all sectors in the near future, education systems need to be overhauled to meet the qualified manpower required by this dynamic process. The ability of companies and institutions with strong information and technology infrastructure to reflect advanced digital technologies to innovation and production processes requires some certain skills, described as 21st century skills. Education 4.0, a reflection of the era of Industry 4.0, refers to a period in which education paradigms, approaches and technologies have been changed. In this study, major technology trends and their reflections on learning and teaching processes are examined within the framework of changing educational paradigms and teaching approaches.

 

Keywords: Education 4.0, Industry 4.0, ICT in education, technology trends
Students' achievement in mathematics: Analysing the influence of gender and school nature
Authors: Bichi Ado Abdu , Suleiman Aisha Hassan , Ali Hauwa
Published: September 2019

This study examined students’ achievement in senior secondary school mathematics qualifying examination in Kano State, the influence of sex and schools nature on their achievement in mathematics has been assessed. Ex-post facto research design was adopted for the study. A pro forma was used to collect data from a sample of 300 students, selected using stratified random sampling procedure from the science secondary schools in Kano state Nigeria. The data collected were the students’ performances in mathematics achievement test. The data were analysed using descriptive statistics and independent sample t-test to test the hypotheses at 0.05, level of significance. Overall results showed that students performed below average and a significant gender difference exists in mathematics performance. Similarly, a significant difference was also observed with respect to schools nature (boarding and day schools); day school students performed above better than boarding school students. The implication of this finding is that despite government continuous efforts, the academic achievement of students in mathematics through above hypothetical pass mark fell below the required average mark for admission into Nigerian universities. It was recommended among others that teachers should regularly motivate students to develop a good study habit and test them on the various mathematics concepts and feedback provided should be used to prepare them for credible achievement in mathematics at both internal and external examinations. Keywords: Gender; mathematics; school nature; students’ performance
Proceso Visionario hacia el Desarrollo Biotecnológico
Authors: Arnáez-Serrano Elizabeth , Moreira-González Ileana , Alvarenga-Venutolo Silvana , Abdelnour-Esquivel Ana , Flores-Mora Dora , Rojas-Chaves Miguel
Published: September 2019

El Centro de Investigación en Biotecnología (CIB), creado en 1994, es la unidad de investigación de la Escuela de Biología del Instituto Tecnológico de Costa Rica. Como ente investigador, el CIB ofrece a la sociedad una serie de servicios técnicos especializados, como producto del conocimiento obtenido a lo largo de una cantidad creciente de proyectos de investigación, que se han desarrollado enfocados en las tres áreas de investigación: Biotecnología Vegetal, Biotecnología Ambiental y Aplicaciones

Biomédicas. Durante los 25 años de su funcionamiento, los investigadores han mostrado un fuerte compromiso para generar ciencia y tecnología con impacto a nivel nacional e internacional. Adicionalmente, las diferentes iniciativas de cooperación entre este centro y otras instituciones son una muestra clara de la dinámica de crecimiento de esta unidad de investigación, tanto en el número de proyectos como en el nivel de los mismos, siendo referente a nivel nacional y regional.
Investigaciones en plantas con potencial bioactivo
Authors: Rosales-López Catalina , Arnáez-Serrano Elizabeth , Moreira- González Ileana , Garro-Monge Giovanni , Agüero-Hernández Ana Laura , Jiménez-Quesada Karol , Abdelnour-Esquivel Ana , Calvo-Castro Laura
Published: September 2019

El Centro de Investigación en Biotecnología (CIB) del Instituto Tecnológico de Costa Rica (TEC), cuenta con un grupo multidisciplinario de profesionales que orientan sus investigaciones en tres diferentes líneas de acción: Biotecnología Vegetal, Ambiental y Biomédica. En el área de Biotecnología Vegetal se desarrollan proyectos que incluyen investigaciones en productos naturales, metabolitos secundarios, compuestos antioxidantes, etnobotánica, bioprocesos, farmacognosia y cultivo de tejidos; todos bajo un mismo objetivo “el uso de recurso biótico como fuente de compuestos bioactivos con efecto positivo sobre la salud, que puedan ser utilizados como coadyuvante o fitofármaco natural para el hombre”. En este artículo se presenta un breve resumen de los proyectos y logros que se han obtenido en esta área de investigación en el CIB.
USING THREE STEPS INTERVIEW TECHNIQUE TO IMPROVE THE SPEAKING SKILLS OF THE NON-ENGLISH DEPARTMENT STUDENTS
Authors: Zainuddin Zainuddin
Published: September 2019

This study was intended to apply three steps interview technique as a teaching technique to solve the problems in the teaching and learning of speaking recount text. The problems were the students had difficulties to understand and respond conversation in English, having grammar difficulties, fluency and content problem and they also had low motivation. The researcher therefore decided to use three steps interview as a teaching technique as an effective solution to solve this problem. The finding of this study showed that implementaation the three steps interview as a teaching technique could help students to speak recount text much better than before when they were taught by using other speaking instruction. 18 out of 19 students passed the 70 as the standard score. In addition, in terms of students’ involvement in the speaking class activity, there was an increase from 81% in Cycle 1 to 87.5% in Cycle 2
ESTIMATION OF CEPHALOSPORINS (CEFTRIAXONE, CEFTAZIDIME) ANTIBIOTICS AS PURE AND PHARMACEUTIC FORMS BY COLOR PRODUCED REACTION IN UV-VIS SPECTROPHOTOMETIC TECHNIQUE
Authors: Al-Rufaie Mohauman Mohammad Majeed , Motaweq Zahraa Yosif
Published: September 2019

A new simple, accurate and low cost-effective UV-VIS spectrophotometric methods has been developed for the analysis of chosen cephalosporins (ceftriaxone, ceftazidime) in bulk samples and pharmaceutical dosage forms by using a specific  color-generated reaction. This method involves the Schiff 's base formation reaction between selected cephalosporins with alcoholic 5-sulfo salicylaldehyde reagent 5SSA with heating to establish a yellow colored product displaying λmax at 426 nm as well as 412 nm sequentially. These methods applied to the Beer’s law through the range of concentration was  (4 - 60 µg.ml-1), (5 -50µg ml-1) respectively for two drugs. The analysis results for these studies  have been tested statistically by the studies of recovery. These methods were successfully applied to the determination of the cephalosporins in bulk form and in Pharmaceuticals additionally it was shown that these methods have equivalent accuracy with the common method(BP)estimation procedures for the studied  drugs. The interferences from frequently taken excipients were  no influence on the estimation process .The study could discover a good  as an employment cost-influence and speed method which that possibility used for making quality control for  these cephalosporin antibiotics.
ANALISIS HUMAN RESOURCE DEVELOPMENT, COMMUNITY DEVELOPMENT, DAN NETWORKING, DALAM MEMPENGARUHI COMPETITIVE ADVANTIGE PERGURUAN TINGGI KEAGAMAAN ISLAM DI INDONESIA
Authors: Sutiah Sutiah
Published: September 2019

Today every university including PTKIN cannot avoid continually being prepared and competing with various other universities both at national and international levels. In winning the competition and replying to higher education the competitive advantage factor is taken into account. High performance of university which is based on three aspects, namely cost-based, product-based, and service-based. PTKIN must have quality and service excellence, as well as the ability to compete in the costs and excellence of majors / study programs offered. There are many factors that influence highly competitive universities, including the factors of human resource development, community development (analysis of community development) and the ability to build networks and cooperation. This study tries to annul the most dominant factors towards competitive advantage . The study took samples of Lecturers and Education Personnel at PTKIN UIN Malang, UIN Surabaya, UIN Jogjakarta, and UIN Bandung using simple random techniques. The sample of respondents is 200 people and check. Statistical analysis used multiple regression components of the Multivariate Principle. Research (1) The results showed (1) All the variables of Human Resource Development (HRD), Community Development Analysis (CDA), and Network Cooperation (NP) related to Competitive Advantage (CA) or PTKIN competitiveness (production quality), quality of service (quality of service), also competitive advantage in financing and quality of safety management (price) unless the CDA converter variable is smaller than the others. (2) HRD variable regression coefficient value of 0.714. Increasing HRD, CA will also increase by 0.714 or 71.4% of the CDA variable value of -0.168. This means, if other factors are considered constant, there is no direct effect of CDA on CA or smaller than HRD and NP because the results are -0.168. While the NP variable value is 0.409. This means, for each increase in NP, CA will also increase by 0.409 or 40.9%. (3) The results of simultaneous testing show differences in variation together between HRD, CDA, NP against CA is 75.8% or accepted 24.2% is used by other factors that are not rejected. From the results of this study, PTKIN is important for developing HR (HRD) and increasing network and quality cooperation (NP) as well as developing CDA to increase PTKIN's competitiveness towards international class or WCU (Word Class University).
From Policy to Practice: Women's Experiences of Breastfeeding-Friendly Worksites, Part 2
Authors: Cheyney Melissa , Henning Margaret , Horan Holly , Bovbjerg Marit L. , Ferguson Maryanne
Published: September 2019

Introduction

Maintaining lactation after returning to work is imperative for overall breastfeeding success, yet mothers who return to full-time employment outside the home are unlikely to meet their breastfeeding goals. Breastfeeding-friendly worksites are one potential solution.

Method

Using semi-structured interviews with employees in one rural New England town (N = 18), we aimed to better understand the barriers and supports to continued lactation at “breastfeeding-friendly” worksites.

Results

Five key themes emerged from participants' narratives; two built environment-focused themes are discussed here.

Discussion

Findings expose the disproportionate burden placed on women when care- and wage-work are combined, even in worksites at least theoretically committed to supporting lactation following a return to work.
Una cigüeña en una higuera, un potro en un tejado, el espejo de Didio Juliano y la máscara de Heliogábalo. Bienvenidos al mundo religioso de los siglos II y III d. C… según la Historia Augusta = A Stork on a Fig Tree, a Colt on a Roof, the Mirror of Didius Iulianus and the Mask of Elagabalus. Welcome to the Religious World of the 2nd and 3rd Centuries A.D... According to the Historia Augusta
Authors: Ballesteros Sánchez Juan Ramón
Published: September 2019

Resumen: El capítulo estudia varios textos con alusiones religiosas de la Historia Augusta desde una doble perspectiva. Por un lado, se describen las alusiones satíricas presentes en estos pasajes. Por otro, se reconstruye la crítica política que contienen estos mismos fragmentos. El objetivo último del trabajo es proponer una lectura coherente para el conjunto de la Historia Augusta. Se analizan varios fragmentos de la Vita Marci (13, 6), la Vita Pertinaci (1, 2-3 y 14,1-3), la Vita Di­dii Iuliani (7, 9-11), la Vita Pescennii Nigri (6, 5-8), la Vita Heliogabali (5, 4-5; 6, 4-5 y 28, 2) y la Vita Alexandri Severi (49, 6) para los que el autor proporciona traducciones originales. La lectura de estos textos permi­te definir el registro historiográfico y la per­sonalidad crítica del esquivo y pícaro autor de la colección de biografías imperiales de los siglos II y III d.C.Abstract: The chapter studies several texts of re­ligious content from the Historia Augusta using a double point of view. On the one hand, are described the satirical allusions present in these passages. On the other, the political criticism contained in these frag­ments is reconstructed. The ultimate goal of this text is to propose a coherent read­ing for the whole of the Historia Augusta. Several fragments of the Vita Marci (13, 6), the Vita Pertinaci (1, 2-3 y 14,1-3), the Vita Didii Iuliani (7, 9-11), the Vita Pescennii Nigri (6, 5-8), the Vita Heliogabali (5, 4-5; 6, 4-5 y 28, 2) and the Vita Alexandri Severi (49, 6) are analyzed throughout the text. The autor provides original translations of all of them. The reading of this corpus allows to define the historiographic record and the critical personality of the elusive and naughty author of the fundamental col­lection of imperial biographies from the II and III century AD.Palabras clave: Historia Augusta, sátira política, religión romana.Key words: Historia Augusta, political satire, Roman religión.
Physics-Based Fluid-Flow Modeling of Liquids-Rich Shale Reservoirs Using a 3D Three-Phase Multiporosity Numerical-Simulation Model
Authors: Jimenez Bruno A. , Aguilera Roberto
Published: September 2019

Production from liquids–rich shale reservoirs in the US and Canada has increased significantly during the past few years. However, a rigorous understanding of shale rocks and fluid flow through them is still limited and remains a challenge. Thus, the objective of our research is developing a 3D physics–based model for simulating fluid flow through these types of multiporosity rocks. This is important given the recent spread of these types of reservoirs throughout the world.

Simulation of liquids–rich shale reservoirs is performed with the construction of an original fully implicit 3D multiphase modified black–oil finite–difference numerical formulation, which uses a multiporosity approach as well as diffusion from solid kerogen. The multiporosity system includes adsorbed porosity, organic porosity, inorganic porosity, natural–fracture porosity, and hydraulic–fracture porosity. A numerical model is developed with capabilities to handle dissolved gas in the solid part of the organic matter, adsorption/desorption from the organic pore walls, viscous– and non–Darcy–flow mechanisms (slip flow and Knudsen diffusion), and stress–dependent properties of natural and hydraulic fractures.

Examples of simulated results are presented as crossplots of pressure, production rates, and cumulative production vs. time. These plots are used to show the contributions of free gas, adsorbed gas, and dissolved gas to fluid production from liquids–rich shale reservoirs. Results indicate that both desorption and gas diffusion positively affect shale performance. Simulation results demonstrate that not taking into account desorption and diffusion from solid kerogen leads to underestimating production from liquids–rich shale reservoirs. Furthermore, the simulation study shows that long periods of time are required for the effects of these two mechanisms to be manifested. This helps to explain why shales have been produced over long periods of time (several decades), such as in the case of Devonian wells in the Appalachian Basin.

The type of 3D simulation model for multiporosity liquids–rich shale reservoirs developed in this paper is not currently available in the literature. The approach implemented in this paper provides a novel and important foundation for simulating complex shale reservoirs.
Simulation Interpretation of Capillary Pressure and Relative Permeability From Laboratory Waterflooding Experiments in Preferentially Oil-Wet Porous Media
Authors: Andersen Pål Ø. , Walrond Kenny , Nainggolan Citra K. L. , Pulido Eliana Y. , Askarinezhad Reza
Published: September 2019

In preferentially oil-wet porous media, laboratory waterflooding experiments are prone to capillary end effects. The wetting phase (oil) will tend to accumulate at the outlet where the capillary pressure is zero and leave a highly remaining-oil saturation at steady state (defined by a stable pressure drop and a zero oil-production rate) compared to the residual-oil saturation. Andersen et al. (2017c) derived analytical solutions describing how the capillary pressure and relative permeability of water (the injected phase) could be determined on the basis of pressure drop and average saturation at steady states obtained at different water-injection rates. Plotting these values against inverse rate reveals linear trends at high rates, with slopes and intercepts that directly quantify the saturation functions in the range of negative capillary pressures. The method is similar to the Gupta and Maloney (2016) intercept theory but quantifies entire functions rather than a single point and provides the trends also at low rates, thus using all the information.

Our aim is to demonstrate how pressure drop and oil production at steady state for different water-injection rates can be used to derive relative permeability and capillary pressure from waterflooding. This is done in three ways. First, synthetic transient waterflooding tests are generated (using a core-scale simulator), applying the same saturation-function correlations as assumed in the analytical solution. Then, more-general correlations are assumed when generating the synthetic data. This is to test the robustness of the analytical solution in producing functions similar to the “true” ones. Finally, we perform a waterflooding experiment in the laboratory on a high-permeability (3 darcies) Bentheimer sandstone core, altered to an oil-wet state. Forced imbibition was started at a rate of 0.4 pore volumes (PV) per day, which was increased stepwise after approaching a steady state. Twelve rates were applied, differing overall by a factor of ≈1,000 to yield states governed by capillary forces and advective forces. The results were interpreted using both full history matching of the transient data and matching of the steady-state data with the analytical solution.

The experimental procedure and model demonstrate that only water relative permeability and capillary pressure determine the steady state during waterflooding, and hence can be estimated accurately. The analytical solution could simultaneously match the trends and magnitude of a steady-state pressure drop and production with injection rate to give an estimation of the saturation functions. The estimated saturation functions from the analytical solution agreed well with the estimates from full history matching.
Online-Group Intervention after Suicide Bereavement through the Use of Webinars: Study Protocol for a randomized controlled Trial
Authors: Wagner Birgit , Hofmann Laura , Maaß Ulrike
Published: September 2019

Introduction The death of a significant person through suicide is a very difficult experience and can have long-term impact on an individual’s psychosocial and physical functioning. However, there are only few studies which have examined the effects of interventions in suicide survivors. In the present study, we examined an online-group intervention for people bereaved by suicide using a group-webinar. Methods The intervention was developed based on focus groups with the target group. The cognitive-behavioral 12-module webinar-based group intervention focuses on suicide bereavement related themes such as feelings of guilt, stigmatization, meaning reconstruction and the relationship to the deceased. Further, the webinar includes testimonial videos and psychoeducation. The suicide survivors are randomized to the intervention or the waiting- list in a group cluster randomized controlled trial. Primary outcome were suicidality (BSSI) and depression (BDI-II), secondary outcomes are symptoms of prolonged grief disorder (ICG-D), PTSD (IES-R), stigmatization (STOSASS) and posttraumatic cognitions (PTCI). Discussion Previous studies of internet-based interventions for the bereaved were writing interventions showing large treatment effects. Little is known about the use of webinars as group interventions. Advantages and challenges of this novel approach of psychological interventions will be discussed.
Is sentinel lymph node biopsy alone accurate for breast cancer mastectomy? Results of a cohort study of 2423 patients.
Authors: HOUVENAEGHEL Gilles , Classe J.M. , Blache G. , Mazouni C. , Reyal F. , Gimbergues P. , Daraï E. , Azuar A.S. , Colombo P.E. , Bannier M. , Lambaudie E. , Cohen M.
Published: September 2019

Backgroud : Few patients with mastectomy and only with pN0(i+) or pN1mi sentinel node (SN) were included in randomized trial. To demonstrate SN biopsy accuracy for mastectomy.
Methods: We examined results of SN among a multi-institutional cohort of patients, <=cT2-N0, who required total mastectomy, according to SN status and complementary axillary lymph-node dissection (cALND) or not. We have analyzed involved non-sentinel node (NSN) rate at cALND, overall (OS) and disease-free survival (DFS).
Results: Among 2423 patients we reported 1307 pN0(i-)SN, 120 pN0(i+)SN, 273 pN1miSN and 723 pN1macro-metastases SN with cALND respectively in 24.5, 73.3, 82.4 and 93.1%. Median follow-up was 42.72 months.
Among 320 patients with pN0(i-)SN we observed 35 NSN macro-metastases (10.9%) and among 723 patients with SN macro-metastases, cALND was omitted in 50 patients (6.9%): in multivariate analysis, OS and DFS were not significantly different according to cALND or not.
Among 120 patients with pN0(i+)SN and 273 with pN1miSN, cALND were respectively omitted in 32 and 48 patients: age, pT-size and SN-status were predictive of NSN involvement. In multivariate analysis, post-mastectomy radiotherapy, regional nodal irradiation and adjuvant chemotherapy were significantly correlated to cALND and a significant lesser DFS rate was reported for patients without cALND (HR: 3.861, p=0.002).
Conclusion: SN biopsy appeared as an accurate procedure for axillary staging of breast cancer mastectomy for pN0 SN status. For pN1-macro-metastases it is not possible to propose to avoid cALND. When SN was involved by ITC or micro-metastases, omission of cALND is still controversial and should have a negative prognosis impact in relation with a down staging and under treatment.
Survival and predictors of early neonatal death in neonatal intensive care unit of Mekelle general and Ayder comprehensive specialized hospitals, Northern Ethiopia, 2018: prospective cohort study
Authors: Kahsay Abrehet Hadera , Abebe Haftom Temesgen , Gebretsadik Letekirstos Gebreegziabher , Tekle Tesfay Hailu
Published: September 2019

Background: Early neonatal mortality refers to deaths of neonates between 0 and 6 days of life. This contributes three-quarters of neonatal deaths globally. Its predictors vary by country with the availability and quality of health care, which was chosen as the measure of mortality and remains a global public health concern especially in sub-Saharan African countries, including Ethiopia. So the aim of this study is to determine incidence, median survival time and to identify the predictors of early neonatal mortality.Methods: A prospective cohort study was conducted in Mekelle general and Ayder comprehensive specialized hospitals, Tigray, Ethiopia from January to March, 2018. Data were collected from 253 newborns admitted to the neonatal intensive care unit by interviewing mothers using structured questionnaires and followed for seven completed days of life (day 0 to 6).Kaplan Meier curves were used to estimate survival time, Log-rank test was used to look statistical differences among/between the categories of variables and Cox regression model was used to identify potential predictors of early neonatal deaths. The analysis was conducted using a computer program Stata version 12.Results: Overall, in this study 32 (12.65%) neonates died which makes the early neonatal mortality rate 126.5 per 1000 live births. The median survival time of early neonates was 2 days. Predictors of early neonatal mortality were very low birth weight (AHR= 3.02; 95 % CI: 1.11, 8.25) and preterm birth (AHR=3.7; 95 % CI: 1.22, 11.188). Conclusion: This study shows high incidences of early neonatal mortality. Very low birth weight and preterm birth were major predictors for early neonatal mortality. Managing complications of preterm and very low birth weight, preventing preterm delivery and improving quality of services and ensuring a continuum of care are recommended to increase survival of early neonate
Professional Early-Adopter Experiences of Implementing a Novel Rehabilitation Model of Care across Alberta, Canada: A Focused Ethnography
Authors: Manhas Kiran Pohar , Olson Karin , Churchill Katie , Vohra Sunita , Wasylak Tracy
Published: September 2019

Background In 2017, a provincial health-system released a Rehabilitation Model of Care (RMoC) to promote patient-centred care, provincial standardization, and data-driven innovation. Eighteen early-adopter community-rehabilitation teams implemented the RMoC using a 1.5-year long Innovation Learning Collaborative (in-person learning sessions; balanced scorecards). More research is required on developing, implementing and evaluating models of care. Understanding RMoC implementation will expand implementation science knowledge, particularly around factors influencing model-of-care outcomes and sustainability in, and between, jurisdictions. We aimed to explore experiences of early-adopter providers and provincial consultants involved in the community-rehabilitation RMoC implementation in Alberta, Canada.Methods Via focused ethnography, we used focus groups (or interviews for feasibility/confidentiality) and aggregate, site-level data analysis of RMoC standardized metrics. Purposive sampling ensured representation across geography, service types and patient populations. Team-specific focus groups were onsite, at participants’ convenience, and led by a researcher-moderator and co-facilitator. A semi-structured question guide promoted discussions on interesting/challenging occurrences; perceptions of RMoC impact; and, suggested definitions of successful implementation. Focus groups and interviews were audio-recorded and transcribed alongside field notes. Data collection and analysis were concurrent to saturation. Transcripts were coded for implementation-related phrases. Similar ideas were collapsed forming themes, with inter-theme relationships identified. Tactics for rigour included negative case analysis, use of thick description, and an audit trail.Results We completed 11 focus groups and seven interviews (03/2018 to 01/2019) (n=45). Participants were 89.6% female, mostly-Canadian trained and represented diverse rehabilitation professions. Teams varied on their focal health service and patient population. The implementation experience involved navigating emotions, operating amongst dynamics, and integrating the RMoC details. Confident, satisfied early-adopter teams demonstrated traits including strong coping strategies; management support; and, being opportunistic and candid about failure. Teams faced common challenges (e.g. emotions of change; delayed data access; and lack of efficient, memorable communication across team and site). Implementation success targeted patient-, team- and system levels.Conclusions We recommend specific training priorities for future teams including evaluation training for novice teams; timelines for step-wise implementation; on-site, in-person time with a facilitator and full-team present; and prolonged facilitated introductions between similar teams for long-term mentorship.
Lean task boards in healthcare, an improvement tool for tidying up the local chaos and promote professionalism
Authors: Antonsen Yngve , Bye Geir
Published: September 2019

Background: A growing number of public healthcare organisations are now implementing the lean task board as a qualitative improvement tool to help solve problems and reduce wasteful work tasks. The task board itself helps line managers and employees to manage, collaborate and prioritize as it can present tasks that are upcoming, in progress or finished. With this focus, the presented paper’s research question is: How do managers’ and employees’ use of the lean task board promote learning for improvement in the municipal healthcare sector? Method: Qualitative case study data from a Norwegian municipality including 750 internal self-recorded logs from task board sessions from six different units and 25 semi-structured interviews of managers and employees. The data were organised based on content and recoded by comparing the codes and finding abstract theoretical patterns. Results: The task board works for line managers to make employees responsible for forwarding ideas, solutions and implementation of new actions. Line managers and employees used the task boards to systemise work through establishing new routines and focus on improving tidiness at work. The task boards were also used as a project management system to track progress in purchasing of diverse equipment and initiatives to improve the units’ facilities. Line managers and employees also set professionalism on the agenda, discussing and improving both daily attitude, work environment and user’s well-being. Senior management with a long-term strategy, support for line managers, and allocation of resources was essential to the implementation of the task boards. Conclusion: The implications from the study are that the lean task board is well suited to promote learning processes that tidy up chaos in local healthcare organisations. Drawing upon action learning theory, the study explains the learning challenges of using the lean task board in municipalities’ healthcare systems, as the method promotes finding experience-based solutions that do not involve critical reflection and use of theory. The task board has limitations as a method for improving services between healthcare units and for solving difficult problems. In light of the findings further investigation is still required to elicit how municipalities organize improvement through lean methods.