bluuebunny/crossref_metadata_2025 huggingface dataset:
El sistema electoral en el Perú: diagnóstico, análisis y propuestas de reforma
Authors: Acevedo Jorge , Ausejo Flavio , Rojas Josefa , Sulmont David
Published: April 2023

Las instituciones políticas como el sistema electoral y el sistema de partidos moldean las reglas del juego bajo las que se practica la democracia. Por ello, con frecuencia se argumenta que, para bien o para mal, entre las reglas de juego democráticas el sistema electoral resulta ser la institución política más maleable (IDEA, 2006, p. 6). El sistema electoral es un conjunto de normas e instituciones a través de las cuales los ciudadanos expresan su voluntad política, dinamizando la vida pública del país. Además, dicho sistema cumple una función reguladora de la ciudadanía y de los partidos políticos mediante fórmulas electorales que cada gobierno elige para legislarse a sí mismo.
Pengaruh Surfaktan terhadap Pemisahan Logam Transisi Periode Pertama Menggunakan Metode Emulsion Liquid Membrane
Authors: Widianti Afifah Rana , Setiani Dwi Ratna , Salsabila Fauzia , Anggraeni Anni , Pratomo Uji , Bahti Husein H.
Published: April 2023

First row transition metals are heavy metals that are very abundant in their compound form and widely applied in industrial fields because of their unique physical and chemical properties. These industrial activities often produce waste that still contains toxic transition metal. To overcome that problems, the transition metal must be separated by an effective and efficient method, that is the emulsion liquid membrane (ELM) because simultaneous separation process. ELM is a separation method that involves three phases. The determinant of the success of the ELM process is the stability of the emulsion which depends on the concentration and type of the surfactant used. Types of surfactants that can be used in the first row transition metal separation using the ELM method are non-ionic surfactants such as Span 80, a mixture of Span 80-Tween 80 and Polyamine ECA 4360J. Therefore, this review article aims to determine the effect of concentrations and type of that surfactants on emulsion stability and extraction efficiency in the separation of first row transition metals using the ELM method.Keywords: First row transition metals, emulsion liquid membrane, surfactant
Redes de aprendizaje profesional docente en contextos escolares chilenos
Authors: Navarro Navarro Luis , Pérez Norambuena José Samuel
Published: April 2023

Aunque las redes docentes de aprendizaje profesional son una estrategia de amplia difusión, hay todavía poca evidencia sobre los significados y condiciones organizacionales que las viabilizan. Este trabajo examinó las valoraciones docentes y, a la vez, los factores contextuales y organizativos que favorecen el desarrollo profesional en la Red de Aprendizaje Docente (RAD) impulsada por un municipio de la región de Ñuble, en el sur de Chile, durante 2018 y 2019. La experiencia fue analizada considerando los aportes de la literatura sobre las comunidades de aprendizaje profesional, las comunidades de aprendizaje en red y las redes de mejora impulsadas por el gobierno chileno. Basado en el análisis temático de los discursos docentes en dos grupos focales, los resultados muestran una positiva percepción sobre la participación en una red colaborativa con docentes de distintos niveles y asignatura, e indican que el trabajo entre pares fue una oportunidad de aprendizaje en temas curriculares, de reflexión compartida sobre sus desempeños, lo que ha significado cierto bienestar personal. En lo que refiere a los aspectos organizacionales para que una red docente opere adecuadamente, los docentes destacan que quienes lideren la red deben evidenciar solvencia y legitimidad pedagógica; debe existir compromiso docente, una planificación que oriente el trabajo y que tenga en cuenta horarios libres para participar. Un hallazgo atípico fue que valoraran el carácter obligatorio de la participación en la red, lo que contrasta con la literatura que enfatiza el carácter autogestionado de estas comunidades.
Beliefs and Practices of Academic Reading and Writing in Researchers in Training
Authors: Franco Jésica
Published: April 2023

This study aimed to examine and explain teachers' and students' reading and writing practices and beliefs in a master's program at a public university in Mexico. We conducted qualitative cross-sectional research. A self-administered questionnaire with open-ended questions was used in the initial stage to examine two distinct beliefs of reading and writing and identify key actors. Six interviews with teachers and students were carried out during the second stage. The study corroborates that the different beliefs are not mutually exclusive but can simultaneously exist in the same person, though they may be weighted differently. Those who firmly hold transmissive beliefs understand that reading and writing are processes to obtain (decode) and transmit (encode) information. In practice, these people emphasize the importance of identifying main ideas, summarizing texts, writing following a structure and taking up ideas from other authors. On the contrary, those who mostly hold transactional beliefs think that reading and writing are creative, dialogic and meaning-construction processes. Some of their reading and writing practices focus on aspects such as: defining a standpoint regarding the text, investigating the context of the author or reader, and defining reading or writing purposes. The research highlights the possibility of reconceptualizing reading and writing in the academic context, valuing their epistemic function and transforming the prevalent discourse that conceives them as technical and universal skills, which can be improved by correctly applying grammatical rules or following effective formulas.
A Study to Compare a CHW-Led Versus Physician-Led Intervention for Prostate Cancer Screening Decision-Making among Black Men
Authors: Martinez-Lopez Natalia , Makarov Danil V. , Thomas Jerry , Ciprut Shannon , Hickman Theodore , Cole Helen , Fenstermaker Michael , Gold Heather , Loeb Stacy , Ravenell Joseph E.
Published: April 2023

Introduction

Prostate cancer is the second leading cause of cancer deaths among men in the United States and harms Black men disproportionately. Most US men are uninformed about many key facts important to make an informed decision about prostate cancer. Most experts agree that it is important for men to learn about these problems as early as possible in their lifetime.

Objectives

To compare the effect of a community health worker (CHW)-led educational session with a physician-led educational session that counsels Black men about the risks and benefits of prostate-specific antigen (PSA) screening.

Methods

One hundred eighteen Black men recruited in 8 community-based settings attended a prostate cancer screening education session led by either a CHW or a physician. Participants completed surveys before and after the session to assess knowledge, decisional conflict, and perceptions about the intervention. Both arms used a decision aid that explains the benefits, risks, and controversies of PSA screening and decision coaching.

Results

There was no significant difference in decisional conflict change by group: 24.31 physician led versus 30.64 CHW led (P=.31). The CHW-led group showed significantly greater improvement on knowledge after intervention, change (SD): 2.6 (2.81) versus 5.1 (3.19), P<.001). However, those in the physician-led group were more likely to agree that the speaker knew a lot about PSA testing (P<.001) and were more likely to trust the speaker (P<.001).

Conclusions

CHW-led interventions can effectively assist Black men with complex health decision-making in community-based settings. This approach may improve prostate cancer knowledge and equally minimize decisional conflict compared with a physician-led intervention.
Contribuições da Teoria da Inoculação e o papel didático da gamificação como ferramenta de combate à desinformação política
Authors: Silva Karoline Maria Fernandes da Costa e , Presser Nadi Helena
Published: April 2023

O artigo explora as contribuições da Teoria da Inoculação e o papel didático da gamificação como recurso de combate à desordem informacional política. Pesquisa bibliográfica, faz um levantamento das principais teorias em torno do conceito de desinformação e, sem seguida, o mapeamento das estratégias de detecção e desmascaramento (debunking) de peças desinformativas existentes no contexto da experiência brasileira, discutindo sua aplicabilidade e viabilidade no “mundo real”. Por fim, apresenta uma abordagem exploratória dos conceitos em torno da “inoculação psicológica” e sua aplicação em games educativos como mecanismo para mitigar os impactos da disseminação de conteúdos falsos ou politicamente nocivos nas redes sociais.
The Preferences of Consumers for Organic Food Products: The Case of Samsun Province in Türkiye
Authors: BAŞKAYA SEZER Duygu , KILIÇ Osman , BAŞER Uğur
Published: April 2023

The decreases in the nutritional value of foods and food safety issues resulting from the methods developed to increase food production have become the most important nutritional problems encountered all over the world. To solve these problems, agricultural and food processing methods are purified from all kinds of chemicals, hormones, and genetically modified organisms. The objectives of this study are i) to determine which of the environmentally friendly and certified organic foods are consumed the most, consumer preferences regarding these foods, the perception of the consumers on the concept/definition of organic food, and the expectations of the consumers after organic food consumption, ii) to compare the perception of organic food concept/definition and post-consumption expectations of organic food consumers and non-consumers. This study was carried out in the Samsun province of Türkiye where 19.6 thousand metric tons/year of organic agricultural products are produced. A total of 480 people participated in the study, of which 240 were consuming organic products and 240 were not consuming organic products. Results and statistical data were evaluated using frequency, descriptive statistics, chi-square, and t-test. According to the findings of study, more than half of the organic products consumed are milk, dairy, poultry, fresh fruit, and vegetable products. Most consumers agree that organic products are hormone-free and produced without the use of chemical fertilizers and pesticides. However, those who are aware that organic products are certified products are mostly organic food consumers. Some participants still consider organic products to be only natural or farmer products. In terms of expectations after organic product consumption, both groups consider that the prices of organic products are high, sales points and marketplaces should be accessible, purchasing attempt depends on income, and organic products are bought due to the positive effects of organic foods on health, environment, and farmers.
EFFECTIVENESS OF SLOW DEEP BREATHING ON PAIN INTENSITY IN CHILDREN THROUGH CIRCUMSISION
Authors: Herliawati Putu Arik , Alivia Hildayanti Rezha , Seri Astuti Ni Luh
Published: April 2023

Background: Circumcision is a surgical procedure that leaves scars and can be quite disturbing for children. This is because of the pain and limited movement that makes the child feel uncomfortable. The response to pain varies from child to child depending on the level of development or age of the child. Slow deep breathing is a conscious action to regulate deep and slow breathing which can have a relaxing effect. Relaxation therapy is widely used in everyday life to be able to overcome various problems such as stress, muscle tension, pain, respiratory problems, and others. Objective: The purpose of this study was to determine the effect of slow deep breathing complementary therapy on reducing pain intensity in children undergoing circumcision at the Marzuki Tabanan Foundation. Method : using pre-experimental method with one group pretest posttest design with purposive sampling technique. Results: From the results of the paired T-test, it was found that P value p: 0.013 <0.05, which means significant or there is an influence of Slow Deep Breathing therapy on pain intensity in children undergoing circumcision.
RELATIONSHIP OF KNOWLEDGE ABOUT SEXUALLY TRANSMITTED INFECTIONS WITH THE SEXUAL BEHAVIOR OF ADOLESCENT WOMEN IN SMKN 5 JEMBER
Authors: Rozana Maulidia Fahmadina , Dwi Jayanti Ratna , Hardianto Gatut
Published: April 2023

Introduction: Adolescence is a period in which hormonal developments affect physical, psychological and cognitive development. At this time adolescents show an interest in sexuality so that adolescents are at risk of contracting Sexually Transmitted Infections (STIs). Many factors can influence adolescent sexual behavior, one of which is knowledge about STIs. Adolescents must have good knowledge to control their sexual behavior in order to avoid sexual behavior that is at risk of STIs. This study aims to analyze the relationship between adolescent knowledge of STIs and female adolescent sexual behavior. Method: This research is an observational analytic study with aresearch design cross sectional. The number of samples as many as 103 teenagers who fit the inclusion criteria. The sampling technique was carried out by total sampling. the independent variable is adolescent knowledge about STIs, while the dependent variable is adolescent sexual behavior. The collected data was tested with thestatistical Fisher Exact Testtest. Results: The results showed that as many as 68 respondents (66.0%) had less knowledge and 35 respondents (34.0%) had good knowledge. The variable of adolescent sexual behavior was found that 90 people (87.4%) had sexual behavior that were not at risk of STIs and 13 people (12.6%) had STI risky sexual behavior. After thecarried out Fisher Exact Test was , the p value = 0.357 (p>0.05) which means that statistically there is no relationship between knowledge about STIs and sexual behavior of adolescent girls. Conclusion: There is no relationship between knowledge of STIs and sexual behavior of adolescent girls at SMKN 5 Jember
The Use of Social Media in Improving Literacy in Rural Village
Authors: Reindrawati Dian Yulie , Setiawan Ferry , Satrianto Muhammad Ditya , Nata Jiwangga Hadi
Published: April 2023

Background: Social media, in the form of chatting platforms such as WhatsApp and various other social media widely used by Generation Y today, can help to increase literacy and information dissemination in a rural village. With the involvement and contribution of Generation Y, social media has what it takes to improve literacy among people in rural areas, allowing them to obtain information as fast and as precisely as the urban communities do while also making advancements to the area itself.
Objective: This study attempts to investigate the use of social media in increasing literacy in eight villages on Madura Island.
Method: This study uses a descriptive analysis method with a qualitative approach.
Results: The results show that there are still several problems caused by the use of social media among generation Y in making decisions, taking action, behaving, communicating, and socializing. Another issue is that, generally, Generation Y tends to disseminate information directly without checking its veracity.
Conclusion: The lack of digital literacy worries many people because it causes the spread of disinformation that threatens the bond of kinship and disperses national unity. Therefore, there is a need for education on how to use social media healthily, provision of rural village and city-level libraries, and the need for attention from clerics, parents, and the government.
Keywords: literacy; rural village; social media
The Effect of Electronic Word of Mouth, Destination Image on Tourist Visiting Decisions at Nagari Tuo Pariangan Tourism Object
Authors: Satifa Putri Yomi , Widyastuti Hardiana
Published: April 2023

Background: Tourism at this time has become one of the critical needs for most people, this can be seen from the increased interest in tourism which is side by side with digital promotion through EWOM in the tourism sector which is rampant on social media. With the high intensity of internet use, especially on social media platforms, making digital promotions through social media provides excellent tourism marketing opportunities.
Objective: This study aims to analyze the effect of electronic word of mouth and destination image on the decision to visit tourists at the Nagari Tuo Pariangan tourist attraction.
Method: The data used in this study were obtained from primary data and secondary data. The data analysis method used is descriptive analysis and SEM-PLS analysis with a sample of 130 respondents, using a non-probability sampling method.
Results: The results of this study indicate that electronic word of mouth has a positive and significant effect on destination image, destination image has a positive and significant effect on visiting decisions, and electronic word of mouth has a positive but not significant effect on visiting decisions. However, there are mediating variables that can influence.
Conclusion: The results of the SEM-PLS analysis also show a positive and significant effect between the electronic word-of-mouth variables on the destination image and decision visit.
Keywords: destination image; electronic word of mouth; the decision to visit; SEM-PLS
Frequency of spondyloarthropathy in patients with end-stage chronic renal failure and receiving renal replacement therapy (hemodialysis)
Authors: ÖZDEMİR Uğur , KAŞKARİ Derya , YÜCEL Ahmet Eftal
Published: April 2023

Objectives: Destructive spondyloarthropathy (dSpA) occurs due to inflammatory destruction of axial joints due to beta2-microglobulin (beta2-M) accumulation in patients with end-stage renal disease (ESRD) receiving renal replacement therapy (RRT). This study aimed to investigate the frequency of dSpA in ESRD patients receiving RRT, by the diagnostic criteria sets of inflammatory back pain (IBP) and inflammatory classical SpA.

Methods: A total of 140 patients were included. The data of the demographic informations, laboratory tests, clinical findings, HLA allele subgroups were collected. Sacroiliac and lateral feet X-rays and if necessary sacroiliac tomography were taken in patients with dSpA related pain. dSpA was investigated according to the Amor and ESSG criteria sets.

Results: Fifty two patients were women (37%). The mean age was 51 ± 15 years. IBP and sacroiliitis were detected in 22 and 28 of the patients, respectively. There was a significant difference according to sacroiliitis and IBP in terms of CRP (p=0.028, p=0.043). dSpA were detected in 21 (15%) patients. Presence of HLA-A1 and duration of HD were determined as independent risk factors for dSpA.

Conclusions: In the diagnosis of dSpA, the character and inflammatory origin of the pain and inflammatory markers should be investigated in addition to the radiological criteria.
Non-Local EPR Correlations using Quaternion Spin
Authors: Sanctuary Bryan
Published: April 2023

A statistical simulation is presented which reproduces the correlation obtained from EPR coincidence experiments without non-local connectivity. We suggest that spin carries two complementary properties. In addition to the spin polarization, we identify spin coherence. This spin attribute is anti-symmetric and generates the helicity. In addition this spin has structure formed from two orthogonal magnetic moments. From these, a resonance spin results from their coupling in free flight. Upon encountering a filter, the resonance spin 1 decouples back into two independent spins of $\frac{1}{2}$, with one aligning with the filter and the other randomizing. The process of decoupling the resonance spin is responsible for the quantum correlation which results in the observe violation of Bell's Inequalities. The polarized states give a CHSH value of 2 while the resonance spin give a CHSH value of 1. Coherence can only be formulated by the existence of a bivector which gives a spin the same geometric structure as a photon. Although this work is not about Bell's theorem, we note that there are no hidden variables (HV). The only local variable is the angle that orients a spin on the Bloch sphere, first identified in the 1920's. The new features introduced are changing the spin symmetry from SU(2) to the quaternion group, $Q_8$, and the introduction of a bivector into spin which leads to an element of reality which is anti-Hermitian. The calculations use standard spin algebra, and properties of quaternions.
Modelling Microsegregation during Metal Additive Manufacturing: Impact of Dendrite Tip Kinetics and Finite Solute Diffusion
Authors: Hariharan V. S. , Nithin Baler , Ruban Raj L. , Makineni Surendra Kumar , Murty B.S. , Phanikumar Gandham
Published: April 2023

Rapid solidification during metal additive manufacturing (AM) leads to non-equilibrium microsegregation, which can result in the formation of detrimental phases and cracking. Most of the microsegregation models, assume a Scheil-type solidification, where the solidification interface is planar and there exists local equilibrium at the interface along with either zero or infinite solute diffusion in the respective participating phases - solid and liquid. This assumption leads to errors in prediction. One has to account for finite solute diffusion and the curvature at the dendritic tip for more accurate predictions. In this work, we compare different microsegregation models that do and do not consider finite diffusion and dendrite tip kinetics against the experiments. We also propose a method to couple dendrite tip kinetics with the diffusion module (DICTRA®) implemented in Thermo-Calc®. The models which accounted for both finite diffusion and dendrite tip kinetics matched well with the experimental data.
Developed Method. Interactions and Their Quantum Picture
Authors: Ogonowski Piotr
Published: April 2023

By developing the previously proposed method of combining continuum mechanics with Einstein Field Equations, explicit equations of interactions operating in a physical system were obtained. The explicit form of the electromagnetic four-potential was also derived, and the Lagrangian and Hamiltonian densities describing the physical system containing all the fields. A quantum picture of the system was also proposed, which, interestingly, allows for a simple transition to a curvilinear description based on the metric tensor in curved spacetime.
Side-Stream Enhanced Biological Phosphorus Removal (S2EBPR) Enables Effective Phosphorus Removal in a Pilot-scale Shortcut Nitrogen Removal System
Authors: Wang Dongqi , Han Il , McCullough Kester , Klaus Stephanie , Lee Jangho , Srinivasan Varun , Huang Mengbo , Wang Zijian Leo , Li Guangyu , Yan Yuan , Li Kailong , Qin Lu , Bott Charles B. , McQuarrie Jim , Stinson Beverley M. , deBarbadillo Christine , Dombrowski Paul , Barnard James , Gu April Z.
Published: April 2023

To meet the growing interest in the development of innovative biological nutrient removal (BNR) alternatives for energy neutrality, resource recovery, and decarbonization, the adsorption/bio-oxidation (A/B) process has been widely studied for carbon capture and shortcut nitrogen (N) removal, while limited research has focused on incorporating enhanced biological phosphorus (P) removal (EBPR), mainly due to the differential carbon usage characteristics of functionally relevant microorganisms. Here, a full-scale pilot testing with an integrated system combining A-stage high-rate activated sludge (HRAS) with B-stage partial (de)nitrification/anammox and side-stream EBPR (HRAS-P(D)N/A-S2EBPR) was conducted treating real municipal wastewater. The results demonstrated that, despite the low influent carbon load, the B-stage P(D)N-S2EBPR system achieved effective and stable P removal performance, especially when the volatile fatty acid (VFA) load from A-stage was elevated. Sludge fermentation in both A-stage and B-stage promoted carbon redistribution and likely provided more competitive advantages for ammonium-oxidizing bacteria and polyphosphate accumulating organisms, leading to carbon-efficient shortcut N removal mainly through partial nitrification pathway and influent carbon-independent EBPR simultaneously. Exposure to high VFA levels was considered a potential selection factor for the suppression of nitrite-oxidizing bacteria in the system. The involvement of internal carbon-accumulating organisms would potentially play an important role in endogenous denitrification. This study provided new insights into the effects of incorporating side-stream EBPR into the A/B process on microbial ecology, metabolic activities, and system performance.
Bio-Insecticidal Potential of Tangerine Peel Oil Against Greenhouse Whitefly: A Green Biopesticide Candidate
Authors: Flores-Mediavilla Nancy Anabel , Prado-Beltrán Julia Karina , Espín-Valladares Rosario del Carmen , Rodríguez-Cabrera Hortensia María , Pais-Chanfrau José Manuel
Published: April 2023

The excessive use of synthetic insecticides in modern agriculture has led to the contamination of the environment and the development of insect resistance. In this study, we evaluated the potential of tangerine (Citrus reticulata L.) peel essential oil (EO) as a natural insecticide against greenhouse whitefly (Trialeurodes vaporariorum W. (Homoptera: Aleyrodidae)), a common pest in greenhouse production. Petroleum ether (PET) and n-hexane (HEX) were used as solvents to extract essential oil (EO) from tangerine peels. The yield of EO was 1.59 % and 2.00 % (m/m) for PET and HEX, respectively. The insecticidal activity of EO was evaluated by measuring the mortality rate (MR) of greenhouse whiteflies at different time intervals. The results showed that PET and HEX extracts of tangerine EO effectively controlled the greenhouse whitefly. With both solvents, it was observed that with doses of 12.5% (v/v), similar results were achieved as with the positive control (corresponding to the commercial insecticide imidacloprid). Additionally, the FTIR analysis found that the EO contained d-limonene, which may be the source of its insecticidal properties. Therefore, tangerine peel essential oil is an excellent natural insecticide candidate for controlling greenhouse whiteflies effectively and sustainably.
Comparative Analysis on Available Technique for the Detection of Covid-19 through CT-Scan and X-Ray using Machine Learning: A Systematic Review
Authors: Majhi Vinayak , Paul Sudip
Published: April 2023

(1) Background: In the year of 2020 Covid-19 was declared epidemic by WHO. From that time millions of people were affected and died by this disease. The main detection process for this epidemic is RT-PCR test or reverse polymerase transcription chain reaction test. One of the reason of spreading of this disease so much is lack of efficiency in RT-PCR test. Sampling error and low viral load were two main reasons for what the testing process faced such problems. Lung infection is a very common symptom for covid-19 patients, so, CT scan and chest X-ray imaging technique can be applied to detect patient at a very early stage of infection. Which will be very effective and also can be a better option to RT-PCR test; (2) Methods: We searched data in Scopus for articles published between 2020 and 2023. The initial set of articles was 189, from which 21 articles will eventually be selected by exclusion criteria; (3) Results: A total of thirteen (61.90%) articles were found working on detecting Covid-19 by extracting the X-ray and CT scan data individually. Three (14.28%) of those articles focused on a hybrid model of CT scan and X-ray Image Data. Another four articles made a comparison between Covid-19, pneumonia and a normal person to identify a Covid-19 patient. Where others have worked on unsupervised learning methods or SVM to detect Covid-19.; (4) Conclusions: We have conducted a systematic review of the studies that have been published up to this time, with the purpose to present a summary of the evidence about the detection of COVID-19. In this article, we have summarized and critically reviewed literatures which worked on development or application or both of different AI or ML technique from chest CT and X-ray images to find a solution to detect covid-19.
Downscaling of Regional Air Quality Model using Gaussian Plume Model and Random Forest Regression
Authors: Kawka Marcin , Struzewska Joanna , Kaminski Jacek W
Published: April 2023

High PM10 concentrations are still a significant problem in many parts of the world. In many countries, including Poland, 50μg/m3 is the permissible threshold for a daily averaged PM10 concentration. The number of people affected by this threshold’s exceedance is challenging to estimate and requires high-resolution concentration maps. This paper presents an application of random forests for downscaling regional model air quality results. As policymakers and other end users are eager to receive a detailed resolution PM10 concentration maps, we propose a technique which utilizes the results of regional CTM (GEM-AQ, with 2.5km resolution) and local Gaussian plume model. As a result, we receive a detailed, 250-meter resolution PM10 distribution, which resembles the complex emission pattern in a foothill area in southern Poland. The random forest results are highly consistent with the GEM-AQ and observed concentration. We also discuss different strategies of data training random forest - using additional features and selecting target variables.
Development of Highly Sensitive Anti-Mouse CD39 Monoclonal Antibodies C39Mab-1 and C39Mab-2 for flow cytometry
Authors: Suzuki Hiroyuki , Kudo Yuma , Tawara Mayuki , Goto Nohara , Ishikawa Kenichiro , Ouchida Tsunenori , Tanaka Tomohiro , Asano Teizo , Nakamura Takuro , Yanaka Miyuki , Kaneko Mika K. , Kato Yukinari
Published: April 2023

CD39 is involved in adenosine metabolism through conversion of extracellular ATP to adenosine. Because extracellular adenosine plays a critical role in the immune suppression of tumor microenvironment, the inhibition of CD39 activity by monoclonal antibodies (mAbs) is one of the important strategies for tumor therapy. In this study, we developed specific and sensitive mAbs for mouse CD39 (mCD39) using the Cell-Based Immunization and Screening (CBIS) method. The established anti-mCD39 mAbs, which were established by the CBIS method including C39Mab-1 (rat IgG2a, kappa) and C39Mab-2 (rat IgG2a, lambda), reacted with not only mCD39-overexpressed Chinese hamster ovary-K1 (CHO/mCD39) but also endogenously mCD39-expressed cell lines, such as L1210 (mouse lymphocytic leukemia) and J774-1 (mouse macrophage-like) cell lines through flow cytometry. Kinetic analyses using flow cytometry indicated that the dissociation constant (KD) of C39Mab-1 and C39Mab-2 for CHO/mCD39 was 7.3 × 10−9 M and 5.5 × 10−9 M, respectively. KD of C39Mab-1 and C39Mab-2 for L1210 was 3.3 × 10−9 M and 3.6 × 10−10 M, respectively. Furthermore, C39Mab-1 could detect the lysate of CHO/mCD39 by western blot analysis. These results indicate that C39Mab-1 and C39Mab-2 are useful for the detection of mCD39 in many functional studies.
Clean Energy Action Index Efficiency: An Analysis in Global Uncertainty Contexts
Authors: Dias Rui , Horta Nicole , Chambino Mariana
Published: April 2023

Climate change, the scarcity of fossil fuels, technical advances in clean energy, and the volatility of crude oil prices are just a few of the factors that have prompted the world to recognize clean energy as a viable alternative to dirty energy. As part of the Paris Climate Accord of 2015, many countries agreed to change their economies to be more sensitive to climate change. Due to this Accord, which increased interest from investors and decision-makers, investments in clean energy companies have benefited [1,2]. Clean energy stocks, which are a part of the larger world of tradable reserves, might experience pricing inefficiencies. In this paper, we investigate the multifractal scaling behavior and efficiency of green finance markets, as well as traditional markets like gold, crude oil, and natural gas between January 1, 2018, and March 9, 2023, which covers periods of low volatility and financial instability (2020 and 2022 events). To test the serial dependency (autocorrelation) and the efficient market hypothesis, in its weak form, we employed the Lo and Mackinlay test and the DFA method. The empirical findings demonstrated that both periods exhibit severe multifractal and significant asymmetry, indicating that the price indices under study are not at all efficient.
Assistência estudantil na educação superior: A trajetória do programa nacional de assistência estudantil na Universidade Federal de Ouro Preto
Authors: Cunha Jacqueline Kelly Almeida , Oliveira Breynner Ricardo de , Fernandes Natália Rigueira
Published: April 2023

O artigo analisa a trajetória do Programa Nacional de Assistência Estudantil (PNAES) na Universidade Federal de Ouro Preto (UFOP), a partir da percepção dos implementadores de alto escalão da instituição. Da mesma forma, pretende analisar os relatórios de avaliação da execução do programa na instituição, no período de 2017 a 2019. O PNAES foi instituído pelo Decreto nº 7.234/2010 com a finalidade de ampliar as condições de permanência dos jovens na educação superior federal, atendendo, prioritariamente, estudantes oriundos de escolas públicas de educação básica ou com renda familiar per capita de até um salário mínimo e meio. Na UFOP, o programa é executado pela Pró-Reitoria de Assuntos Comunitários e Estudantis, que define os critérios e a metodologia de seleção dos alunos de graduação beneficiados. A pesquisa é quanti-qualitativa, descritiva e se estrutura em três fases: (1) levantamento dos marcos legais/institucionais do programa a nível nacional e local; (2) análise dos dados disponíveis na UFOP sobre a avaliação da execução do PNAES na instituição, no período de 2017 a 2019; (3) e entrevistas com os burocratas de alto escalão, responsáveis por ações de implementação do PNAES na PRACE. Os dados analisados revelam que, entre 2017 e 2019, em média 11.141 alunos estavam matriculados no ensino presencial na instituição. Destes, 60,7% são egressos de escola pública e 25,2% receberam auxílio financeiro via PNAES. Sobre o desempenho acadêmico, os dados informam que os bolsistas têm melhor coeficiente médio que os demais alunos, além de menor evasão. Os dados indicam que o programa na universidade contempla estudantes oriundos de escolas públicas em situação de vulnerabilidade socioeconômica, contribuindo para a redução de desigualdades sociais por meio da inserção e da permanência dos alunos e, consequentemente, da conclusão do ensino superior.
Análise do perfil de egressos dos cursos de licenciatura da Universidade Estadual do Maranhão no ENADE (2008-2017)
Authors: Duarte Ana Lúcia Cunha , Gomes Suzana dos Santos , Alves Kallyne Kafuri
Published: April 2023

O artigo analisa o perfil de licenciados(as) em Instituições de Educação Superior (IES) a partir de dados produzidos em pesquisa de âmbito nacional dirigida por diferentes universidades públicas. Se desenvolve a partir da problemática de analisar o perfil dos estudantes das IES, com atenção aos Projetos dos Cursos de Biologia, Letras, Matemática e Pedagogia no âmbito dos estudos teóricos-metodológicos da rede UNIVERSITASBr. Utiliza como procedimento a análise dos dados do Exame Nacional de Desempenho dos Estudantes (ENADE) no período de 2008 a 2017. Recorta os dados relativos às categorias de: renda mensal, trabalho e perspectiva de renda no período, escolaridade dos pais, motivação na escolha do curso, cor e raça e instituição de conclusão do Ensino Médio. Os resultados indicam que durante os anos analisados houve avanços nos referidos cursos, como o ingresso de familiares no ensino superior e o incentivo de professores da rede pública à inserção em cursos de licenciatura. Verificamos também desafios, como a demanda por investimento, especialmente no curso de Pedagogia, com atenção às perspectivas profissionais de cursistas. Por fim, compreendemos que a reformulação dos cursos de licenciatura, propostos pela BNC-formação, evidencia ameaças à dimensão docente de formação de pedagogos(as), o que pode sugerir desconsideração dos indicadores do Enade na elaboração de políticas públicas.
Neurological Complications After Covid 19 Vaccinations: Serial Case Report
Authors: Sari Intan Permata , Prabaningtyas Hanindia Riani
Published: April 2023

Background: COVID-19 vaccination has been carried out worldwide, with more than 5 million dose of vaccine delivered. Although declared safe, there are cases of neurological disorders after the Covid 19 vaccination.
Cases: In the first case, a 20-year-old male came with decrease level of consciousness, 4 days after receiving the first dose of COVID 19 vaccine with Sinovac vaccine. MRI Brain shows acute disseminated encephalomyelitis (ADEM). In the second case, a 50-year-old male with seizures and decreased consciousness after recieving first dose of COVID-19 vaccination with Sinovac vaccine, 10 days before admission. Non contrast CT Scan and brain contrast MRI Brain revealed cerebral edema. In the third case, an 18-year-old woman had seizures and decreased consciousness one month after the first dose of COVID 19 vaccination with Sinovac. Contrast Head MRI showing focal leptomeningitis. In the fourth case, a 30-year-old male with slurred speech and right-sided weakness. Three months before admission, he had fever, headache, and tingling of the right limbs a few days after the first dose of COVID 19 vaccination with Sinova MRI Brain Contrast shows ADEM lesion
Discussion: The mechanism of neurological disorders concerning COVID 19 vaccination is still unclear. Neurological complications after vaccination weaken the effort of vaccination, but can be used as a precaution and assess prognosis while waiting for further confirmation from large epidemiological studies and meta-analyses. Until now, it is believed that the COVID-19 vaccine has important benefits and is a hope for ending the COVID-19 pandemic.
Platelet Rich Plasma Effects on Diabetic Foot Ulcers - A Review
Authors:   Department of Pathology, Jinnah Sindh Medical University, Karachi, Pakistan., Zia Shamail , Salam Abdul ,   Department of Medicine, Allama Iqbal Medical College, Lahore, Pakistan., Nusrat Sanam ,   Department of Surgery, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan., Khan Muhammad Hamza ,   Department of Medicine, Shaikh Khalifa bin Zayed Al Nahyan Medical College, Lahore, Pakistan, Chunchu Venkata Anirudh ,   Department of Medicine, Avalon University School of Medicine, Willemsta, Curacao, Nawaz Hassan ,   Department of Medicine, Nishtar Medical University, Multan, Pakistan., Hassan Danial ,   Department of Healthcare Profession, Ministry of Public Health Qatar, Doha, Qatar, Zehra Tatheer ,   Department of Pediatrics, Allied Hospital, Faisalabad, Pakistan., Zia Fazail ,   Department of Pathology, Noor E Zia Consultant Clinics, Karachi, Pakistan., Shamail Farozaan ,   Department of Pathology, Noor E Zia Consultant Clinics, Karachi, Pakistan.
Published: April 2023

Abstract: Utilizing platelet rich plasma, one of the newest autologous cellular therapies, as an adjuvant therapy in a regenerative medicine management, can be very beneficial. Patients with complications like osteoarthritis, spinal disorders and musculoskeletal problems still facing global lacking in the area of tissue repair strategies. Along with this another major complication associated is with diabetic patients - the development of diabetic foot ulcers that predisposes to limb amputation. To advance the healing process and prevent the patients from progressing towards amputations. Besides many other approaches used. Platelet Rich Plasma (PRP) therapy is attaining momentum, which is composed of platelet growth factors that assist the wound healing cascade – inflammation, proliferation and remodeling. It may occur because of provision of vital growth factors necessary for healing. Currently, variety of PRP formulations have been assessed. The article intends to evaluate the PRP effectiveness for managing diabetic ulcers.
Cutaneous Epithelioid Angiomatous Nodule with Unusual Localization
Authors:   Department of Pathology, Izzet Baysal Training and Research Hospital, Golkoy, Bolu, Turkey, Ozer Songul Peltek
Published: April 2023

Abstract: Brenn and Fletcher described cutaneous epithelioid angiomatous nodule (CEAN) as a benign vascular proliferation that was in 2004. It is very rare condition. It is characterized by endothelial cells that have histiocytoid appearance. It is generally found in the dermis or sub cutis and rarely, in visceral organs. Despite the etiology of CEAN is not clear, it is considered as a reactive entity and no association with either infection, trauma or immunosuppression has been described yet. A 76-year-old woman visited hospital for routine examination. The physician noticed an erythematous nodule on the upper part of her right labium minus which appears like a cystic lesion. Histopathological examination revealed a relatively circumscribed, unencapsulated, unilobular vascular lesion which is in the superficial dermis. There were also moderately lymphoplasmacytic infiltration on the background. There were also scattered extravasated erytrocytes around. Positive stained for CD34, CD31 and negative stained for HHV-8 (performed to rule out a possibility of Kaposi sarcoma), pancytokeratin and s-100 were prominent in epithelioid cells. The overall histopathological appearance was consistent with CEAN and there was not any previous report CEAN occurring at this area.
About Genesis of Chinese Philosophy
Authors:   Far Eastern Federal University, Kononchuk Dmitry V.
Published: April 2023

The article discusses the processes that at the turn of the VI–V centuries B.C. were evolving to give rise to the authentic philosophical tradition in China. The author considers the formation of a community of people who keep themselves within the framework of certain reflective practices as the hallmark of this rise. The evolution set off during the “Iron Age Cold Epoch” that occurred on the planet in the early 1st millennium B.C. The civilizational response to this cool­ing in China was the extensive development of agriculture, which, in turn, led to demographic growth, the enhancement of the socio-political structure of society and the emergence of demand for competent managers. The social base for them turned out to be the lowest nobility – the “officers” shi. Unlike the aristocrats zhuhou at the highest tier of power, the “officers” shi were interested in main­taining the moral status of the “noble person” junzi. The existential space of this status could only be maintained through permanent reflection. The criterion for maintaining one’s moral status was not only social behavior in accordance with this status, but also its existential experience, devotion not to external factors, but to an internal idea, responsibility to oneself. The Confucian effort to compre­hend and to pass on those reflective practices became the beginning of Chinese philosophy
Political Philosophy in the Treatise Kong-zi Jia Yu
Authors:   Institute of China and Contemporary Asia, Russian Academy of Sciences, Blazhkina Anastasia Yu.
Published: April 2023

The article examines the key aspects of political philosophy, reflected in the Con­fucian treatise Kong-zi jia yu (Speeches of the Confucius school). The essence of the political doctrine in the searched text is the concept of governing the coun­try on the basis of virtue (de) and with the help of the law (fa), which pre­supposes political leaders have the highest forms of morality; considers one of the main functions of the state as the implementation of a program of spiritual guidance for the people through the education of ritual decency (li) and the es­tablishment of cultural norms (wen).One of the characteristic features of Confu­cian politics is that it represents the logical conclusion of Confucian ethics. Con­fucian political doctrine is a national etatism. The ultimate goal that it sets is a harmonious condition of society, understood as a return to the ancient ideal of the Great Unity (da tong), including the material well-being of the people (fei).Achieving such a state should be achieved through the implementation by gentleman (jun-zi) of an effective program for the transformation of the country (tianxia). A gentleman is understood as an ethical model for the people, and has the main moral constant of a political leader – humanity (ren)
The Cognitive Strategy by Gu Yanwu
Authors:   Institute of China and Contemporary Asia, Russian Academy of Sciences, Ionov Aleksey Yu.
Published: April 2023

This article is devoted to the views on the goals and objectives of cognition of Gu Yanwu (1613–1682), the founder of the critical philosophy in China. These views, originally associated with the military-political projects of the Chi­nese elite of the Ming era and reflecting the strategy of the struggle for national sovereignty during the Manchu conquest of China, had a serious impact not only on the Confucian tradition of the following centuries, but also on modern Chi­nese studies. The concepts by Gu Yanwu were formed in the conditions of the emergence of new ideas about the world associated with the penetration of European knowledge and inventions into China. Because of his research con­cerning cognitive processes in the era of the collapse of the former Chinese and the emergence of the new Manchu official ideology, Gu Yanwu was able to ra­tionally explain the evolution of the Confucian tradition. His rejection of neo-Confucianism and the search for other orientations of intellectual activity were derived from the desire to preserve the Confucian heritage after the death of the Ming Dynasty. The former neo-Confucian attitude to the synthesis and con­sistency of knowledge, which has a practical application in eliminating differ­ences in descriptions of phenomena and events, has been replaced by an attitude to the analysis of knowledge and verification of the reliability of its source, also implying the verification of knowledge by practice. Gu Yanwu was the first to include field studies of geographical objects in essays on the standard Confucian issues of political culture and public administration. The idea of Yijing studies as the frameworks of Confucian tradition is fundamental to Gu Yanwu’s critical theory of cognition.
Overcome Hardness by Hardness, Overcome Hardness by Softness: comparing The Tale of Igor’s Campaign and Records of the Grand Historian
Authors:   Hebei Normal University, Xiaoli Guo
Published: April 2023

The Tale of Igor’s Campaign and Records of the Grand Historian are classic books of Russian and Chinese antiquity. Both of them are based on historical facts and combine the features of “literature, history and philosophy”. The main characters of the both works contain deep-rooted characteristics and typical fea­tures of the national cultures. Firstly, Igor was brave and resolute and went on a campaign for glory. Liu Bang assessed the situation, sacrificed his reputa­tion, saved his life and waited for an opportunity to strike back. One considers an attack a defense, and the other considers a retreat an offensive. Secondly, both of them behave rationally, their behavior is determined, respectively, by the de­sire for fame and the desire to preserve life. One considers glory, imbued with heroism and consciousness of suffering, as the goal of life. And according to an­other, humiliation and preservation of life are prerequisites for achieving victory. Thirdly, the pursuit of fame and the pursuit of life have different consequences. In Russia, “victory on the verge of defeat” can bring sanctity and a sense of glory. In China, the best solution is to “throw back the enemy’s troops without a fight”.