bluuebunny/crossref_metadata_2025 huggingface dataset:
Factores que Afectan a la Adopción de las Tecnologías 4.0 en las Empresas del Sector del Mueble
Authors: Muñoz-Puche Almudena , Jiménez-Zarco Ana Isabel , Izquierdo-Yusta Alicia
Published: November 2023

El propósito del presente estudio ha sido determinar qué factores tecnológicos, organizacionales y ambientales afectan a la adopción de las tecnologías 4.0 en las empresas del sector del mueble. El sector del mueble es una industria caracterizada por su dinamismo y por la gran intensidad de su mano de obra. Pese a la importancia del sector, en la actualidad sigue siendo una industria muy tradicional, con una minoría de empresas que han adoptado la industria 4.0. En este contexto, se llevó a cabo este estudio para investigar, mediante un análisis cualitativo a través de nueve entrevistas en profundidad realizadas a expertos del sector, qué factores afectan más a la adopción de tecnologías 4.0 en el sector del mueble. Los resultados indican que los factores organizacionales influencian más en la adopción de tecnologías 4.0, sin embargo, todos no afectan de la misma forma: algunos facilitan dicha adopción tecnológica, mientras que otros la inhiben.
DUALIDADE, INTEGRAÇÃO E FUSÃO MILITAR-CIVIL NA INDUSTRIA DE DEFESA.
Authors: Moura José Augusto Abreu de
Published: November 2023

A indústria de defesa é formada por empresas e órgãos do Governo. Como as outras, se insere na economia da nação condicionada pelos aspectos de oferta e demanda inerentes às particularidades de seus produtos, serviços e tecnologias empregadas. Assim, este artigo analisa a forma pela qual a Base Industrial de Defesa (BID) brasileira interage com os agentes econômicos por comparação com a França, os Estados Unidos da América (EUA) e a China. A dualidade civil-militar é a forma básica e ocorreu inicialmente com a aplicação no meio civil de tecnologias empregadas em material militar (spin-off) e, depois, também ao contrário (spin-in). Tal divisão desvaneceu com a apropriação das mesmas tecnologias pelos dois setores e a premência de promover a Inovação. Nesse contexto, seguiu-se a Integração, iniciada pelos EUA, mas seguidos pela França, com a participação na BID de empresas antes não incluídas e uma abertura das normas, possibilitando maior aplicação militar de produtos comerciais. A China aprofundou essa integração com uma reforma da ciência, tecnologia e indústria relacionadas com a defesa, para construir capacidades estratégicas nacionais integradas, a que chamou de Fusão Militar-Civil. Na comparação, o Brasil se aproxima da França, buscando maximizar a dualidade, com alguns aspectos de integração.
O PROTAGONISMO DO PODER AEROESPACIAL NOS ESTADOS UNIDOS E SEUS REFLEXOS NO DESENVOLVIMENTO DA INDÚSTRIA AERONÁUTICA BRASILEIRA
Authors: Matos Patricia de Oliveira
Published: November 2023

As duas grandes guerras, a consolidação do poder aeroespacial como elemento decisivo nos conflitos e o advento da tecnologia nuclear tiveram profundos impactos na indústria e na estruturação de um sistema de CT&I nos Estados Unidos, no qual grande parcela dos investimentos públicos voltou-se para o desenvolvimento do setor aeroespacial. Esse modelo de desenvolvimento econômico, pautado na influência militar e na centralidade do poder aeroespacial, ainda se faz presente nos EUA (Eliasson, 2010; Ruttan, 2006; Medeiros; 2007). No Brasil, na década de 40, surgiram as primeiras iniciativas para a criação do Instituto Tecnológico de Aeronáutica (ITA) que tornaria possível, anos mais tarde, o desenvolvimento da indústria aeronáutica brasileira. A concepção do ITA foi proposta pela FAB, mas contou com a participação do Departamento de Engenharia Aeronáutica do Massachusetts Institute of Technology (MIT). Esses passos iniciais, que contaram com uma aproximação entre Brasil e Estados Unidos, no contexto da Segunda Guerra Mundial, e com certa emulação da política de desenvolvimento aeroespacial dos EUA, não explicam toda a trajetória da indústria aeronáutica brasileira, mas estão na origem de uma rara e bem-sucedida política industrial do país. A percepção dos militares brasileiros sobre o poder aeroespacial como elemento fundamental à estratégia militar moderna, além da noção de que este poder envolveria não apenas a obtenção das aeronaves, mas a capacidade de produzi-las, foi fundamental para as primeiras iniciativas brasileiras no setor. Desde então, a política industrial que permitiu a sustentabilidade de uma empresa de alto conteúdo tecnológico e elevada inserção internacional, parece uma exceção quando comparada a outros setores industriais no Brasil (Ferreira, 2021; Medeiros, Trebat, 2017). Neste trabalho, procura-se investigar, por meio de revisão da literatura e fontes documentais, como a centralidade assumida pelo poder aeroespacial na estratégia militar e no modelo de desenvolvimento industrial dos EUA influenciaram no surgimento e na consolidação da indústria aeronáutica brasileira.
GOVERNANÇA DA BASE INDUSTRIAL DE DEFESA: PANORAMA SOBRE A RELAÇÃO ENTRE CT&I E PODER MILITAR NA ATUALIDADE
Authors: Silva Peterson Ferreira da
Published: November 2023

A complexidade crescente de determinados equipamentos militares tem salientado o debate sobre a importância de margens de autonomia tecnológica, bem como da capacidade de resposta industrial no âmbito da base industrial de defesa. Especialmente tendo em vista os desdobramentos recentes do conflito entre Rússia e Ucrânia (2022-), constata-se que deter capacidade industrial de defesa continua sendo um fator relevante para o poder militar. Porém, alguns elementos desse quadro sofreram transformações recentes, o que suscita tanto vulnerabilidades quanto oportunidades no campo da segurança e defesa nacionais. Nesse contexto, o objetivo deste artigo é identificar tendências na relação entre Ciência, Tecnologia & Inovação e poder militar na atualidade. Utilizando-se de revisão bibliográfica e documental, sobretudo no que se refere ao período 2014-2023, este artigo aponta a interação crescente entre os setores comerciais e de defesa, assim como a relevância de priorização na gestão de recursos de defesa nacional. Como conclusão, é possível reafirmar o papel central que o poder de compra do Estado possui na governança da base industrial de defesa em vários países.
PALAVRAS-CHAVE: Defesa Nacional; Base Industrial de Defesa; Forças Armadas.
BASE LOGÍSTICA DE DEFESA: O INSTRUMENTO DE DEFESA ESTRATÉGICO PARA O PREPARO E SUSTENTAÇÃO DO EMPREGO DE CAPACIDADE MILITAR.
Authors: Brick Eduardo Siqueira
Published: November 2023

O preparo de capacidade militar de um país é a atividade mais importante para sua defesa. É, também, a mais comum e permanente, porque tem que ser desenvolvida tanto em períodos de paz, quanto de conflitos. Portanto, não é exagero dizer que ocupa as atenções das autoridades responsáveis pela defesa durante 100% do tempo. Ora, atividade tão estratégica, ubíqua e relevante, deveria receber uma enorme atenção da Academia, em especial dos programas de pós-graduação vocacionados para estudos de defesa. O cerne da questão de defesa, no nível estratégico do preparo de capacidade militar, são as decisões envolvendo soluções de compromisso entre alocações bilionárias do orçamento, durante largos períodos de tempo, para os diversos componentes de capacidade militar. Sem uma base conceitual sólida, consensual e aderente à realidade do preparo da defesa, essa tarefa é praticamente impossível, porque envolve inúmeros governos que se sucedem ao longo do tempo. Sem essa base conceitual que pacifique o entendimento de conceitos básicos, tais como capacidade militar, logística de defesa, instrumentos de defesa e gestão estratégica da defesa, o mais provável de acontecer serão intervenções erráticas e, mesmo, que se auto anulam, de vários governos sucessivos. Este artigo, então, se propõe a estabelecer um arcabouço conceitual que possa ser usado para desenvolver atividade tão estratégica para a defesa de um país.
AS CONTRIBUIÇÕES DA ARTE PARA UM DESENVOLVIMENTO HUMANO INTEGRAL
Authors:   , santos David Dos
Published: November 2023

Os cientistas do desenvolvimento humano buscam investigar os processos de mudança e estabilidade que os seres humanos experimentam ao longo da vida. Para estabelecer parâmetros de "normalidade", eles estabelecem padrões de acordo com o período de vida. Desde o período pré-histórico, a maioria dos seres humanos entra em contato com algum tipo de obra de arte, ou até mesmo a (re)elabora, portanto, busca-se investigar quais são as influências da arte nos processos de desenvolvimento humano. Para isso, uma revisão bibliográfica foi realizada com abordagem qualitativa nas bases de dados SCIELO e na Biblioteca Virtual em Saúde (BVS). Os principais resultados indicam que a arte estimula funções cognitivas e psicológicas superiores, contribui para contextos educacionais e de saúde pública, além de contribuir para o bem-estar subjetivo.
Two Papyrus Fragments with Historically Relevant Data
Authors: Demarée Robert J.
Published: November 2023

This small article is a foretaste of the richness in historical data provided by the thousands of papyrus fragments contained in the archives from the ancient workmen’s community of Deir el-Medina now gradually consultable in the online database TPOP. 

ملخص

هذه المقالة الصغيرة هي لمحة موجزة عن المعلومات التاريخية الغنيّة جداّ التي تحتويها آلاف قطع البردي حول المجتمع القديم للعمال في دير المدينة والمحفوظة في الأرشيف والتي يمكن في الوقت الحاضر الاطلاع عليها ضمن TPOP، وهي منصة البردي في تورينو على الإنترنت.
Isolation and characterization of bacteria from babies heat prickly powder purchased in Umuahia, Abia state
Authors: Goodluck Chigozie Okwuokei  , Janet Ginikachi Okafor  , Ibukun Akinboyewa  , Cyril Arinze Eji  , Ojinika Dabeluchukwu Ononye  , Chidinma John  , Collins Kelechi Chukwu  , Prince Chiugo Chidi  , Joseph Ochigbano  , Hope Olileanya Nwaobia
Published: November 2023

Aim: To isolate and Characterize Bacteria from Babies Heat Prickly powders purchased in Umuahia, Abia state Method: A total of Ten (10) Baby heat prickly powder samples were randomly purchased from different market locations in Umuahia, Abia state. Isolation and identification of Bacteria were conducted using standard microbiological techniques. Bacteria were Characterized using standard microbiological and biochemical test. Results: The isolated Bacteria include Staphylococcus aureus, Bacillus sp, Staphylococcus epidermidis and Pseudomonas aeruginosa. Staphylococcus aureus had the highest percentage occurrence (40%) while other Bacteria had (20%) each with the total bacteria count (TBC) ranging from 4.3 ×104 CFU/g to 1.32 ×105 CFU/g. Conclusion: High bacterial load was observed in the present study which showed there was contamination of most of the products in respect to the international Microbiological standards recommended limits for bacterial contamination in powder/Cosmetic products (1.0 x 103 CFU/g) for bacteria. This could be as a result of poor manufacturing practices, poor hygiene, contaminated raw materials or the susceptibility of the ingredients contained in the baby powders.
Effects of rock phosphate and PK mineral fertilizer on soil fertility and cocoa production in south-central Côte d'Ivoire
Authors: Acka Jacques Alain KOTAIX  , Guy Fernand YAO  , Evelyne Gévère Marise ASSI  , Klotionoma COULIBALY  , N’Dri Norbert KOUAME  , Sandotin Sounta COULIBALY  , Koffi Hypolith KOUADIO  , Koffi Stanislas KOUAKOU  , Walet Pierre N’GUESSAN  , Diby Balet Françoise GOGBE  , Koffi Emmanuel KASSIN  , Louis Anselme KOKO  , Mandela Elogne N’DOUBA  , Kouamé Antoine N’GUESSAN  , Gnion Mathias TAHI
Published: November 2023

Côte d'Ivoire is the world's leading cocoa producer, but sustainable cocoa production is threatened by, among other things, the country's dwindling forest reserves and declining soil nutrients, mainly phosphorus. To remedy the decline in soil fertility, a study of a mineral amendment was carried out in south-central Côte d'Ivoire to ensure the sustainability of cocoa production. Specifically, the aim was to evaluate the effects of rock phosphate (RP) and PK mineral fertilizer on soil fertility and cocoa production at Divo, over three years of trials. The experimental set-up was a Fisher block design, with 4 replications for 5 treatments. The results showed that, in terms of soil fertility, treatments receiving rock phosphate generally had good assimilable phosphorus content (≥ 11.5 Cmolkg-1), a Ca/Mg ratio of between 1 and 1.5, Mg/K≥3, (Ca+Mg)/K of between 12 and 40 and Ca/SBE x100 ≥ 68%. These ratios reflect not only good cocoa-growing soil, but also a good balance between Ca and the sum of exchangeable bases (SBE) and between K and the sum of Ca and Mg. On the other hand, all treatments had potassium deficiencies with (K/S) x100 < 8%. As for yield, treatments T1 (100%RP + 100% NPK 0-23-19) with 2953.44 Kgha-1, T2 (90%RP + 100% NPK 0-23-19) with 2962.95 Kgha-1 and T3 (80% RP + 100% NPK 0-23-19) with 2862.10 Kgha-1 were the most expressive.
Nutritional and anti-nutritional properties of sweet cassava (Manihot esculenta) and black pepper (Piper nigrum) leaves
Authors: Fowomola Moshood Abiodun  , Girigisu Sadisu  , Yusuf Kudirat Sade
Published: November 2023

The proximate compositions,some minerals,some vitamins and antinutrients contents of sweet Cassava (Manihot esculenta) and Black pepper (Piper nigrum) leaves were investigated on dried weight basis by employing the standard methods described by the Association of Official Analytical Chemists (AOAC, 1990)., Association of vitamin chemists (1987) and Harborne. (1973). The results showed that Sample A (sweet cassava leabes ) contained crude protein (11.70 ± 2.34%), Hexane extract (1.47 ± 0.1%), Ash content (1.90 ±0.1%), crude fibre (3.56 ± 0.14%), moisture (10.8 ± 0.00%) and carbohydrate (70.57 ± 0.45%).while Sample B(black pepper leaves ) contained crude protein (8.73±1.25%), Hexane extract (1.49 ± 0.1222%), Ash content (1.82 ± 0.141%), crude fibre (2.92 ± 0.141%), moisture (12.81 ± 0.00%) and carbohydrate (78.46 ± 1.25%). The results also revealed that Sample A contained potassium (155.75 ± 1.02 mg/100g), sodium (3.82 ± 0.14 mg/100g), calcium (2.47 ± 0.1 mg/100g), magnesium (75.28 ± 0.60 mg/100g), manganese (0.44 ± 0.10 mg/100g) and copper (0.17 ± 0.01 mg/100 g). Sample B on the other hand, contained potassium (164.45 ± 0.387 mg/100 g), sodium (4.80 ± 0.01 mg/100 g), calcium JJ(3.65 ± 0.223 mg/100 g), magnesium (94.75 ± 0.223 mg/100 g), manganese (0.10 ± 0.001 mg/100 g) and copper (0.17 ± 0.01 mg/100 g). The results of vitamin analysis depicted that Sample A contained vitamin A (0.116 ± 0.01IU), vitamin B1 (0.032 ± 0 mg/100 g), vitamin B2 (0.0027 ± 0 mg/100 g), vitamin B6 (0.125 ± 0 mg/100 g), vitamin B12 (0.024 ± 0 mg/100 g), vitamin C (17.80 ± 0 mg/100 g), vitamin E (0.012 ± 0 mg/100 g) and vitamin K (0.002 ± 0 mg/100 g). While Sample B contained vitamin A (0.114 ± 0.01 IU), vitamin B1 (0.0765 ± 0.038 mg/100 g), vitamin B2 (0.0435 ± 0.038 mg/100 g), vitamin B6 (0.1245 ± 0.022 mg/100 g), vitamin B12 (0.033 ± 0.031 mg/100 g), vitamin C (15.72 ± 0.282 mg/100 g), vitamin E (0.014 ± 0 mg/100 g) and vitamin K (0.00165 ± 0.036 mg/100 g).The results of antinutrient analysis also depicted that Sample A contained Tannin (0.3655±0.038 mg/100 g), saponin (0.2855 ± 0.0387 mg/100 g), Alkaloid (0.1025 ± 0.1025 mg/100 g), phytate (0.2815 ± 0.0387 mg/100 g), oxtate (0.195 ± 0.0316 mg/100 g), glycocyanide (0.005 ± 0.001 mg/100 g) and flavnoid (0.58 ± 0.04 mg/100 g). However, Sample B contained Tannin (0.357 ± 0.031 mg/100 g), saponin (0.293 ± 0.031 mg/100 g), Alkaloid (4.551 ± 0.114 mg/100 g), pytate (0.347 ± 0.031 mg/100 g), oxtate (0.233 ± 0.0446 mg/100 g), glycocyanide (0.005 ± 0.001 mg/100 g) and flavonoid (0.6425 ± 0.05 mg/100 g). Therefore, dried sweet cassava and black pepper leaves are good soourses of proteins, carbohydrates, fibre, potassium, vitamin C and flavonoids. Black pepper leaves also rich in alkaloid.
Dynamicity of hydrogels and their diverse biological applications
Authors: Snehal Devram Albhar  , Shreya Ravindra Jekate
Published: November 2023

Ever increasing use of hydrogels in various sectors of biology imposes the need of rigorous study of various aspects related to it. Its compatibility with the biological system makes it suitable candidate to achieve any complex application of such hydrogels in living systems. Depending upon the need, it can be modified chemically which in turn gives it desired physical properties. These modifications enable us the wide spectrum use of hydrogels for various purposes. Nature of response given by prepared hydrogels greatly varies according to the protocol followed while preparing such hydrogels. Slight change in the composition of hydrogels changes its properties and forms entirely new features bearing form. The overall architecture of hydrogel is designed in such a manner that it can be applicable in various regenerative and biomedical applications and still further modified to be used in novel different application fields. This review highlights preparation techniques being followed to fabricate hydrogels which are having major applications in biological fields. Properties of various hydrogels depending upon their compositions and material which give them new face and can be extrapolated to the new research area have also discussed further
Communication as an evolutionary factor of knowledge, from primordial organisms to complex collective systems
Authors: Bruno Riccardi  , Sergio Resta  , Giacomo Resta
Published: November 2023

The intrinsic characteristic of material substances is their ability to modify their physical state and their energy content in response to the interactions and stresses they receive. And it is the capacity that crosses transversely all living matter including man, with the difference that the man solicited by external events becomes aware of his own uniqueness and his own destiny. We can say that man acquires human characters when he learns to re-know his fellow men and the world around him and experiences the wonder that this experience transmits him. And we will show how the whole of the multiplication of contacts and interactions between men produces the corpus of knowledge of peoples. Starting from this hypothesis, in this work we are going to describe how the transformations produced by the reciprocal interactions between material substances, and between these and their environment, are acquired in the form of knowledge. The analysis of the events we describe of the cognitive process follows the logical procedure, which will lead us to the conclusion that knowledge is the intrinsic manifestation of matter and how it originates and takes shape from it. With the advent of man, the highest expression of the organization of matter and knowledge, matter itself embodied in man can investigate knowing itself and its intimate essence. Thus, knowledge can be conceived as the virtuous ontological circuit that originates from matter and returns to it modified in form and enriched with content.
Determinants of online shopping behavior for organic vegetable products through digital marketing platforms
Authors: Windi Lestari  , Laila Husin  , DwiWulan Sari
Published: November 2023

This research aims to analyze factors that can influence online organic vegetable purchasing behavior through digital marketing platforms. The sample of respondents in this study used a quota sampling technique, consisting of 10 shops/outlets that sell organic vegetables online. From the 10 shops/outlets, 20 respondents were obtained for each, so the number of respondents in this study was 200 people. The analytical method used is PLS Structural Equation Modeling (SEM) analysis. The results of this research show that consumers' online buying interest in organic vegetable products is directly influenced by personal factors and consumer psychological factors and indicators of interest in using the technology acceptance model, but is not influenced by cultural factors, social factors and consumer technology acceptance model factors . The factual online purchasing factors of consumers of organic vegetable products are directly influenced by personal factors and consumer buying interests.
Nomophobia, a disease linked to mobile phone addiction: A descriptive study among university students
Authors: Orlando Andrés Sosa-Delgado  , Melissa Janeth Ayala-Rojas  , Stephanie Damaris Pineda-Yupanqui  , Jaime Tony Flores-Ramos  , Karen Elisa Julca-Santos  , Juan Morales
Published: November 2023

Objective: To determine the frequency of nomophobia and its associated factors among university students. Materials and methods: A cross-sectional descriptive study was carried out in the first academic period corresponding to 2023. The sample consisted of university students from three private universities located in the northern area of the city of Lima. The manifestations of nomophobia were measured with the Nomophobia Scale (NMP-Q). Results: A total of 372 students of both sexes participated, with a median age of 22 years (Q1=20, Q3=29, IQR=9). Regarding frequency, 14.8% (n=55) had no nomophobia, 65.6% (n=244) were at risk of nomophobia, and 19.6% (n=73) were nomophobic. The manifestations of nomophobia, as well as the risk of nomophobia were mainly presented in students aged between 21 and 30 years, with a frequency of 50.7% (n=37) and 46.3% (n=113), respectively (p=0.029). Conclusion: Nomophobia among university students is a frequent problem and mainly affects young adults in their third decade of life. It is important to promote self-care regarding the manifestations of nomophobia in the university community.
The effect of roselle (Hibiscus sabdariffa l.) flower petal extract on smear layer removal of crown dentin
Authors: Christian Khoswanto  , Fatina Jilan Rahman  , Hendrik Setiabudi
Published: November 2023

One of the initial stages carried out before making a restoration is the tooth preparation. The debris resulting from the preparation process of the tooth structure is called the smear layer. Dentin conditioner is needed to remove the smear layer so that the crown dentin surface is clean and the restoration can adhere well. Roselle (Hibiscus sabdariffa L.) are a herbal ingredient that has acidic properties found in its flower petals. This research was conducted to determine the effect of roselle flower petal extract on the removal of the smear layer on crown dentin. Eight human maxillary first premolars from orthodontic extraction patients were used as samples. This pre-experimental study was conducted with a test group consisted of control group conditioned with sterile distilled water and treatment group with 2,5%, 5%, and 10% of roselle flower petal extract. The research data was obtained through observing the results of scanning Electron Microscope (SEM). Roselle flower petal extracts 5% and 10% were able to clean the smear layer better than extracts with a concentration of 2.5% and the control group. This may be due to the acidic pH of the solution and demineralization process caused by the presence of citric acid and other organic acids in roselle flower petal extract.
Sustainable business models and grassroots frugal innovations in developing countries
Authors: Abdullahi Giza Abubakar  , Ibrahim Abubakar Sadiq  , Dan’asabe Godwin Geyi  , Mukdem Mark Dabok  , Shamsuddeen Musa Aujara  , Rahmat Muhammad Loko
Published: November 2023

This research explores the origins and evolution of frugal innovations (FIs) within the grassroots communities of developing countries. It scrutinises how these innovations employ inventive business models that hold promise for sustainable development. The analysis centers on distinct aspects of business models, primarily elucidating the concepts of value proposition, value creation, and value capture. FIs, as this study reveals, possess the transformative ability to convert marginalised and underserved populations at the grassroots level into innovative consumer segments. Through an in-depth exploration of three compelling FI (Technology Hub, Albarka Yoghurt and JK Innovation) case studies, this research significantly contributes to the existing literature concerning FI business models. These cases vividly illustrate how individuals constrained by limited access to education, capital, and resources can ingeniously bring affordable products to market, employing unconventional strategies to fulfil the unmet needs of underserved demographics in developing nations."
The effect of orthodontic treatment with premolar extraction against the temporomandibular joint and masticatory muscles: A review
Authors: Anis Irmawati  , Christianto Rici Walujo  , Yassir Ahmad Azzaim  , Barakat Al-Tayar  , Noor Faizah Balqis
Published: November 2023

Temporomandibular joint (TMJ) is a hinge joint that connects the maxillary and mandibular bones between the head of the mandibular condyle and the temporal bone. Removing premolars can cause Temporomandibular Disorder (TMD) which is still debated due to diagnostic errors or errors in mechanotherapy during treatment. Most of the literature states that there is no scientific evidence that premolar removal is a risk for TMD. However, orthodontists should still be aware of anterior tooth contact during orthodontic treatment due to incisor retroclination, deepening of the bite, and incisal interference. The use of low force is still the mainstay for anterior retraction so that there is no decrease in vertical dimension due to loss of anchorage. Achieving the centric relation is the ideal goal of orthodontic treatment, so determining the pre-treatment centric relation is essential. Orthodontic treatment generally tends to improve rather than worsen TMJ conditions. Purpose: This study aims to describe changes in the TMJ and masticatory muscles after orthodontic treatment with premolar extraction. Conclusion: Several studies have shown no significant difference in masticatory muscles before and after orthodontic treatment with extraction.
Mycosis Fungoides: Case report of progression successfully treated with liposomal doxorubicin
Authors: Juan Sebastián Lopera Valencia  , Diana Margarita Otero de la Hoz
Published: November 2023

Mycosis fungoides is the most common primary cutaneous T-cell lymphoma. It is a non-Hodgkin lymphoma that begins in the skin and is characterized by a slow clinical evolution of three stages: macules, plaques and tumors. The advanced stage includes lymph node, visceral, or blood involvement, and requires skin-directed therapy associated with systemic medications. The case of a 49-year-old female patient with a diagnosis of mycosis fungoides in the malar region since July 2019 is presented, initially treated between November 2019 and March 2020 with 3 cycles of the CHOP chemotherapy regimen - cyclophosphamide, doxorubicin hydrochloride (hydroxydaunorubicin), vincristine sulfate (Oncovin) and prednisone without achieving any clinical response. Subsequently without follow-up or treatment. In February 2023, progression of the disease was documented due to worsening of the lesion in the malar region and involvement of the glutes and back, additionally with cervical lymphadenopathy but without bone marrow involvement. She is considered a candidate for liposomal doxorubicin, with which she has completed 5 cycles to date with excellent clinical response. Current reassessment studies using positron emission tomography show complete tumor response. A bone marrow transplant is the therapeutic option that is being considered at the moment.
UPAYA PERLINDUNGAN SATWALIAR UNTUK MEMPERTAHANKAN KEANEKARAGAMAN HAYATI DI NEGERI HUTUMURI, KECAMATAN LEITIMUR SELATAN, KOTA AMBON
Authors: Latupapua Lesly , Sahusilawane Jhon
Published: November 2023

Indonesia is a country blessed with abundant natural wealth and various types, both flora and fauna. This is motivated by the position of Indonesia which is located between two geographic regions of fauna, namely Asia and Australia, with the Wallacea line connecting the two regions. These conditions have made Indonesia one of the countries with the nickname of mega biodiversity in the world. Maluku is included in the geographical area of ​​Australia with a group of islands spread from the north of Halmahera Island to the south of Southwest Maluku Regency, making Maluku rich in fauna potential, one of which is wild animals. However, hunting and illegal wildlife trade pose a serious threat to the preservation of wildlife in Indonesia and Maluku. Wild animals that are traded illegally based on various facts found in the field are caught from nature, not from captivity. Protected and endangered species of wild animals are also still traded freely. Departing from the problems found, community service activities with the topic "Socialization of Wildlife Protection Efforts to Preserve Biodiversity in Hutumuri Country, South Leitimur District, Ambon City. The activity will be held in November 2022. It is hoped that from the PKM activities, the community will understand and be made aware of the potential for natural wealth that they have, it should be preserved and maintained for both current and future generations.
PENGUATAN LEMBAGA ADAT “KEWANG” DALAM KONSERVASI SUMBER DAYA ALAM DI DESA HARUKU
Authors: Sahureka Mersiana , Sahupala Andjela
Published: November 2023

Kewang is one of the Customary Institutions whose function is to regulate the use and protection of natural resources both on land and at sea. The role of the Kewang Customary Institution in Haruku is maximally related to the function of supervision/controlling of community activities convert the mangrove forest ecosystem which is the lompa fish habitat. In addition to the activities of the people who hunt and take eggs from scorched birds freely. The goals to be achieved from Community Service activities carried out in Haruku country are 1. Rehabilitation of mangrove forest ecosystems as lompa fish (Trisina baelama) habitat, 2. Improving partners' abilities and skills in carrying out mangrove cultivation techniques, 3. Increasing partner supervision on the presence/population of gosling birds. The method used to transfer science and technology is 1). Preparation,  2). The implementation stage consists of: counseling and training, procuring mangrove seeds/saplings and making nurseries, planting, making scorched bird breeding cages, carrying out maintenance of mangrove plants that have been planted in the field and at the nursery location. The results achieved in this activity were making nurseries and planting 1000 mangrove saplings, building 2 bird brooding cages, cleaning the beach, counseling on mangrove cultivation and nursery techniques, the Role of Indigenous Institutions in the Management of Natural Resources, Breeding of rare fauna.
Nota editorial
Authors: Gil Ruiz Juana María
Published: November 2023

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Autorías
Authors: Acfs Tecnico
Published: November 2023

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CALCULATION OF MATERIAL QUALITY CRITERIA USING FRACTAL THEORY
Authors: VOLCHUK V.M. , KASHYNA N.V. , KOTOV M.A. , HAIDAR A.M. , KASHYN D.O.
Published: November 2023

Problem statement. Changing the parameters of standard technology can significantly change the properties of rolled iron in a wide range of values. Regulatory and technical industry documentation regulates only the hardness indicators of cast iron rolls, and the requirements for mechanical characteristics and wear resistance are not indicated due to the influence of many technological parameters. Therefore, an important aspect is the prediction for quality indicators of cast iron due to the use of mathematical modeling, in particular the theory of fractals. Materials and methods. Cast iron rolls with a pearlite matrix were studied. The mechanical properties of the working area for cast-iron graded rolled rolls produced by OJSC “Dniprovskyi zavod protnykhnykh valkov”, Dnipro, were determined on standard equipment using INSTRON and CD-40 machines, PSV 5 pendular digger, Shore hardness tester. The microstructure of the rolls was analyzed at a magnification of 200 times. The results of the experiment. As a result of the experiment, it was established that the best among analyzed sensitivity of mechanical properties to dimensional characteristics of carbides is observed for fractal, information and correlation dimensions. Therefore, it is advisable to use these dimensional estimates of carbides in the future to predict the mechanical properties of the working zone for rolled iron with lamellar graphite. To predict the mechanical properties of rolled cast iron with lamellar graphite, it is advisable to use dimensional estimates of graphite and carbides with an increase in the structure of ´200. Conclusions. The analysis of the obtained results showed the promise of using the theory of multifractals for the quantitative assessment of the structural elements of rolled cast iron rolls with a complex geometric shape. This approach makes it possible to use statistical estimates of the dimensions of graphite and carbides to predict and correct the quality indicators of roll metal according to the obtained equations (3-6) along with traditional methods of quantitative metallography, which evaluate their geometric characteristics: shape, distribution, dimensions (length, diameter) and content.
STRUCTURE AND PROPERTIES OF THE ETRINGITE PHASE
Authors: DEREVIANKO V.M. , KONDRATIEVA N.V. , HRYSHKO H.M.
Published: November 2023

Problem statement. Aluminate and sulfoaluminate cements are not produced in Ukraine, despite a rather significant need for binders of this class. The use of imported raw materials is limited by the high cost and certain disadvantages occurring during exploitation including rapid hardening, significant heat generation, which is associated with instability of some sulfoaluminates. At the same time, it is possible to highlight the following problems in the direction of expanding possibilities of using special cements of this type: stabilization over time and operating conditions of the hydrosulfate phase based on alumina cement, as well as modification of the compositions of mineral binders based on calcium sulfate dihydrate (CaSO4·2H2O) and development of binders of this class based on secondary production products. The main factor is that during hydration of sulfoaluminates and aluminates in the presence of gypsum (CaSO4·2H2O), a hydrosulfoaluminate phase is formed, which makes it possible to obtain a hardened cement paste structure with special properties. Then monocalcium hydrosulfoaluminate turns into hydrosulfoaluminate of the low-sulfate form С3А·СaSO4·12H2O with the release of gibbsite Al2O3·3H2O. Also, ettringite С3А·СaSO4·nH2O and 2(С2S)·nH2O is formed and hydrated calcium silicate CSH(B) can be formed. When gypsum is added to cement, ettringite is formed in this system. Etringite is one of the components. It is not formed initially, but through intermediate structures. During hydration reactions, ettringite is rearranged, neoplasms are formed, which can lead to gypsum corrosion. Etringite loses its stability. Herewith, the problem of primary and secondary ettringite arises. Primary ettringite creates conditions for strength. Secondary ettringite is formed already in the hardened system and leads to internal stresses. Formation of secondary ettringite can have both positive and negative consequences. The purpose of the atrticle is to investigate structure and properties of the ettringite phase. Conclusions. The hydration process depends on the Gibbs surface energy. Change in surface energy depends on the CaO/Al2O3 ratio. It was established that the surface energy increases with an increase in the CaO/Al2O3 ratio. The paper has studied influence caused by the ettringite phase on the main characteristics of alumina cement and gypsum in a modified gypsum binder. Studies have been conducted on formation of the maximum amount of ettringite phase. We have calculated the maximum amount of the ratio of alumina cement and gypsum to obtain the maximum amount of mineral – 70 % alumina cement and 30 % gypsum. The highest effect is achieved during the simultaneous use of С6АṤ3Н32 and АН3, which occurs during hydration of С4А3Ṥ. Taking into account the above, it is advisable to obtain clinker containing calcium sulfoaluminate and cements based on it.
MODELLING THE INFLUENCE OF WELDING MODES ON THE MECHANICAL PROPERTIES OF WELDED JOINTS
Authors: PILIUGIN Yev.D. , ROTT N.O. , MYRONENKO M.A. , DMYTRIYEV A.V. , TVERDOKHLIB O.M.
Published: November 2023

Introduction. Welding is one of the most common and effective methods of joining metal structures, which is used in many industries, from the automotive to the oil industry. However, in the process of welding, the joints are subjected to significant thermal and mechanical loads, which can lead to defects and a decrease in the mechanical properties of welded joints. The main part. Modelling the influence of welding modes can be performed using various methods, such as mathematical modelling based on the laws of physics and mechanics, experimental studies of welded joints and their analysis, or a combination of these methods. Basically, finite element methods, boundary element method, finite difference method, and hybrid modelling method can be applied, where, for each individual element of influence on welding, the most effective method of mathematical modelling is used. It is considered what software can be used for modelling a mathematical model. The methods of experimental research used to determine the mechanical properties of a welded joint are analyzed. The methods of comparing experimental data to the mathematical model are also analyzed. Conclusions. The basic methods of mathematical modelling of welding, methods of experimental research, and comparison of the obtained data of the mathematical model with the conducted research have been considered. Based on the comparison, it is possible to find out how a particular welding mode will affect the quality of the welded joint.
RESEARCH OF PRODUCTION TECHNOLOGY AND PROPERTIES OF THE BLADE IS MADE BY THE MINE WELDING METHOD
Authors: VOLCHUK V.M. , KACHUR V.I. , TIUTIERIEV I.A.
Published: November 2023

Problem statement. One of the main requirements for the blade is to achieve significant indicators of corrosion resistance and elasticity, the ability to withstand lateral and contact loads. Thanks to the combination of high-carbon and stainless steels with the help of pit welding, the effect of zone hardening is achieved in the subsequent heat treatment. Zone hardening technology is a combination of different hardness indicators on one knife blade, which leads to a significant increase in the elasticity and durability of the blade, reduces the risk of hardening cracks. Mine welding allows you to combine into a composite steels that have a high content of carbon (С = 0,9…1 %, С = 0,4…0,45 %) and chromium (Cr = 13…14 %), which with an ordinary electric arc method is practically impossible to do. High carbon equivalent and chromium doping complicates existing welding processes. With the appropriate modes of thermoplastic deformation, we get in the zone of forge welding a monolithic connection of two steels at the atomic level, which in itself is already a composite (combination of two materials with different properties to obtain a third starting material). Materials and methods. Etching the blade in an acid solution. To obtain blanks for blacksmithing (pit welding), we took steel bar ШХ15Ш (ТУ141594 DSTU4738:007) Ø – 20 mm, length L − 80 mm for the cutting part of the blade, steel bar 40Х13 DSTU 7838:007, for covers Ø − 20 mm, L − 150 mm. The total weight of the package is 0,42 kg. The results of the experiment. When conducting four experimental attempts to determine the tempering temperature-time regimes for a composite knife blade (ШХ15Ш in 40Х13 facings), the following parameters were obtained: 1. heating temperature 260…270 °С; 2. exposure for 1,8…2 hours; 3. cooling − air. The hardness of the blade is 58−59 HRC, the cutting part is 52−54 HRC of the coating. With such indicators, the maximum indicators of wear resistance of the cutting edge and high indicators of blade elasticity were obtained. For steel n690: 1. heating temperature for tempering 200…220 °С; 2. exposure for 1 hour; 3. cooling − air. Conclusions. Knife blades are proposed to be made by manual forging, without the use of pneumatic and hydraulic hammers, to ensure the purity of the experiment. The work includes calculations of heat treatment regimes, analysis of the microstructures of the obtained monosteel and composite, economic feasibility, advantages and disadvantages of one method of obtaining a blade blade over another.
Biliary diseases: from universal treatment programs to personalized solutions
Authors: Shcherbynina M. B.
Published: November 2023

Objective —  to inform practicing doctors about the possibilities of using the drug Сholoplant®‑Tau in diseases of the biliary system and for the prevention of gallstone disease. Biliary diseases are represented by a wide spectrum of pathology. Among them, both functional disorders and a number of organic conditions with a predominance of gallstone disease (GD) are identified. In recent years, the number of patients with chronic cholecystitis has doubled. In general, there is a rapid increase in the number of cases of the GD disease worldwide. In view of the evolution of the state of the biliary system towards the deterioration of the patients’ health, the use of passive diagnostic and treatment tactics by doctors is not approved. The drugs that have the most physiological mechanisms of correction, is the basis of modern therapy. The combination of components with hepatoprotective and choleretic activity is considered the most promising. Сholoplant®‑Tau (Propharma Plant LLC, Ukraine) belongs to such agents for restoring and maintaining the function of the liver, biliary tract, and gallbladder. The peculiarity of it is a unique combination of 4 components: artichoke leaf extract (Cynara scolymus L.) 200 mg, angelica root extract (Angelica sinensis) 50 mg, ursodeoxycholic acid (UDCA) 100 mg and taurine 100 mg.

Information is provided in the form of questions and answers, which reflect the key points of patient management to obtain a better clinical result. The experience of application by Ukrainian doctors has been highlighted. The paper is aimed at practicing doctors.

Conclusions. The four components of the drug Сholoplant®‑Tau (artichoke, angelica, UDHC, taurine) complement and enhance the effect of each other, which contributes to the effective normalization of the functions of the entire hepatobiliary system, stimulates the increase in the production of bile and bile acids, normalizes the intestinal microflora, eliminates inflammation and ulcerative spasms of the gallbladder and intestines. Сholoplant®‑Tau is a good choice for solving many problems of the biliary system.
A clinical case of fatty liver disease. How the new nomenclature can be applied in practice
Authors: Manzhalii E. G.
Published: November 2023

Metabolic dysfunction‑associated steatotic liver disease (MASLD) is an urgent problem, as this condition is diagnosed in about 35% of the world’s population. Manifestations of metabolic dysfunction in MASLD include excessive body weight (abdominal obesity is the most dangerous), manifestations of dyslipidemia, hepatomegaly, signs of diabetes, arterial hypertension, and moderate alcohol consumption (> 20 g/30 g of alcohol per day in women and men, respectively). According to a new meta‑analysis, MASLD significantly increases the risk of cardiovascular, metabolic, oncological and reproductive consequences. This disorder was associated with a significantly increased risk of cardiovascular outcomes (hazard ratio [HR], 1.43), metabolic outcomes such as incident hypertension (HR, 1.75), prediabetes (HR, 1.69), diabetes (HR, 2.56) and metabolic syndrome (HR, 2.57), chronic kidney disease (HR, 1.38), and various liver‑related outcomes (HR, 3.92). MASLD is also associated with all types of cancer (HR, 1.54); the highest risk is observed for hepatocellular carcinoma (HR, 4.37). Currently, there are no FDA‑approved drugs for the treatment of MASLD, but there are some drugs to treat comorbidities with potential benefit in MASLD that may be considered in the appropriate clinical setting. It is important to understand that MASLD is a complex and multifaceted condition that requires a comprehensive approach to diagnostics and treatment, in addition to the approach of a gastroenterologist‑hepatologist alone. The increasing MASLD prevalence will remain a major global health threat that requires the implementation of effective mechanisms of the disease management.

The authors present a clinical case of metabolic dysfunction‑associated steatohepatitis, associated with the I degree obesity. Liver dysfunction, metabolic and asthenovegetative disorders were revealed on the basis of complaints, anthropometric and anamnestic data, and the results of laboratory studies. Treatment with the use of S‑adenosylmethionine (Agepta, manufactured by Italy, developed by the company Omnifarma, Ukraine) was proposed, which contributed to the stabilization of indicators, according to the data of repeated clinical examinations. The lifestyle changes, physical activity, compliance to the treatment scheme and doctor’s recommendations enabled improving the patient’s state of health.
The impact of saccharolytic and proteolytic fermentation products in the pathogenesis of metabolic associated diseases. Review
Authors: Gridnyev O. Y. , Buriakovska O. O. , Chereliuk N. I.
Published: November 2023

The article highlights the research data on the role of saccharolytic and proteolytic fermentation products in the pathogenetic mechanisms of the development of metabolically associated diseases. A brief description of the composition, number and function of the normal intestinal microbiome is given. Data on the peculiarities of saccharolytic and proteolytic fermentation in the intestines are given. The role of the gut microbiota in the formation of such metabolically associated diseases as obesity, type 2 diabetes mellitus and non‑alcoholic fatty liver disease has also been described. The influence of short‑chain fatty acids, namely propionate, succinate and butyrate, in regulating the metabolism and secretion of insulin, leptin, as well as satiety hormones, namely glucagon‑like peptide 1 and peptide YY, is given in detail. The effects of proteolytic fermentation products on the metabolism and functioning of the intestine‑liver axis, as well as on the processes of carbohydrate metabolism, are carefully described. Descriptions of the effects of protein fermentation products of intestinal microbiota on intestinal pro‑inflammatory reactions and the progression of non‑alcoholic fatty liver disease are provided. The combined data, obtained from rodent and human investigations, regarding effects of short‑chain fatty acids on adipose tissue metabolism. In particular, the ability of acetate to inhibit intracellular lipolysis in adipocytes has been proven. The effects of essential short‑chain fatty acids on intestinal permeability are also described. The most important role of short‑chain fatty acids in the development of inflammatory processes, in particular low‑grade inflammation characteristic of metabolically associated diseases, is emphasized. The data have been presented from investigations of the role of acetate, butyrate and propionate in non‑alcoholic fatty liver disease and type 2 diabetes mellitus.