bluuebunny/crossref_metadata_2025 huggingface dataset:
The Music of Amy Grant
Authors: Gill Mary ,   Religious Communication Association
Published: November 2024

This study examines the rock musical forms and lyrics chosen by Amy Grant by comparing them to traditional Christian principles. For purposes of this comparison traditional Christian principles are understood to be a primary belief in one God and Jesus Christ as His Son. In as much as Grant's music is consistent with this belief, her style may be considered traditionally Christian; however, religious leaders and musicians have criticized her style and message. This study attempts to determine to what extent Grant portrays a traditional Christian perspective through her music. A major contributor to understanding the intent of Grant's music stems from an understanding of her ideology of life, the Christian faith, and the role of Gospel music. Four representative songs are analyzed: "Thy Word," "Where Do You Hide Your Heart," "In a Little While," and "Straight Ahead." Songs which closely follow scriptural texts, such as "Thy Word," clearly contain a traditional Christian perspective. Songs which refer to God or Jesus Christ as "He" or "Him," were found to represent a traditional Christian perspective though not explicitly.
The Clowning Glory
Authors: Graves Michael P. ,   Religious Communication Association
Published: November 2024

Religious clowning has become a prevalent and effective form of communication among Christians in America. This essay seeks to answer two questions relevant to the phenomenon of clown ministry: (1) What is the essential rationale for clowning that establishes it as a viable religious communication activity? and (2) To what practical uses may clowning be put in the life of religious organizations? In response to these queries, the paper develops a rationale for religious clowning based upon an analysis of the implications of the clown as symbol and a review of several practical applications of religious clowning both in the worship life of the church and in broader ministry situations.
The Ethics of Interpersonal Influence
Authors: Fulkerson Gerald ,   Religious Communication Association
Published: November 2024

This article uses a Judeo-Christian understanding of dialogic communication to examine and critique the strengths and weaknesses of rhetorical sensitivity.
Parables and the Oral Medium
Authors: Bineham Jeffrey L. ,   Religious Communication Association
Published: November 2024

Contemporary Western culture's dependence on the print medium sets it apart from the oral cultures of the preliterate, preprint age. This paper argues that dependence on the print medium blinds people to the relativity of their interpretive contexts. Thus the movement from oral tradition to print tradition has led away from a tendency for metaphorical interpretations of God's relationships with people toward a tendency for literal interpretations of God's nature. A metaphorical theology which makes parables central to religious language can help to recapture some of the positive characteristics of oral culture.
Teaching a Habit
Authors: Pasini Enrico ,   Zeta Books
Published: November 2024

The focus of this paper will be, on the one hand, on a prime example of the historical issues and practices related to the teaching of the habits involved in the art of artificial memory: on Lambert Schenckel, a didactic genius, possibly the most important teacher that the tradition of the art of memory ever saw; on Martin Sommer, his follower and betrayer; on the true history of the Gazophylacium artis memoriae. This, on the other hand, will allow us to highlight relevant aspects of the seventeenth-century reshaping of certain habits of the human mind, setting them on a background where the habit-forming practices on which the art of memory is based, and their teaching, can be seen not so much as a merely instrumental component, but rather as a relevant social phenomenon in themselves, that accompanies a seemingly contradictory transformation of individual and social needs.
Reiner Schürmann and (Onto)Theology
Authors: Schrijvers Joeri ,   DePaul University
Published: November 2024

This article explores Schürmann’s relation to religion and theology. Since the publication of his early essays in Ways of Releasement (2023), Schürmann scholarship will find new ways to think about Schürmann’s troubled relation to religion. This article will name some significant traits that surface in these early papers: First, Schürmann’s sense for the mystery, which will, however, quickly vanish from his thinking. Second, the growing influence of Heidegger from 1966 onwards. Third, an increasing departure from determinate religion through a reading of Eckhart, and a growing taste for a universal experience, first, of the mystery, and then of “borrowed being.” Our aim is to show Schürmann’s farewell to religion and theology through succumbing to Heidegger’s critique of ontotheology, which, for Schürmann, seems to have spelled the end of theology.
Mobbingin Kariyer Planlama Üzerindeki Etkisi
Authors: Gündoğdu Yağmur
Published: November 2024

Mobbing, çalışma hayatında bulunan her birey için hem psikososyal hem de fizyolojik olarak etkileyen ve bireylerin haklarını ihlal eden bir süreçtir. Mobbing kavramındaki temel nokta, bireyin sürekli olarak isteyerek ve sistematik olarak belirli davranışlara maruz bırakılmasıdır. Mobbing kavramı, neredeyse bütün örgütlerde ortaya çıkabileceği gibi her bireyin mobbinge uğrama olasılığı da vardır. Bu doğrultuda, bu çalışmada mobbing genel olarak tartışılmış olup, kariyer planlaması üzerindeki etkisine değinilmiştir.
The Role of Guidance and Counseling in Students' Learning Problems at School
Authors: Yulianti Yulianti , Zubaidah Zubaidah , Amalianita Berru , Sarman Freddi
Published: November 2024

This study intends to explore the role of guidance and counseling in addressing student learning problems at school. The method chosen for this article is Literature Review. The method in this research is using a literature review approach. A literature review is a study that has the aim of searching and analyzing in a comprehensive, structured, without doubt and may be repeated process. This approach is used because of similarities and relevance in systematically assessing all studies related to the role of guidance and counseling in schools. This research consists of 5 articles starting from 2019-2023. Based on the study analysis, it shows that guidance and counseling have a significant role in helping students overcome various learning problems, such as academic difficulties, low motivation, interpersonal conflicts, and others. A holistic approach based on individual needs can provide effective support for students in developing their potential optimally. The implication of these findings is the need to increase the role and support for counselors and teachers in providing quality guidance and counseling services in educational institutions. It is hoped that this study will be able to contribute to improving the understanding and practice of guidance and counseling in schools in order to develop learning outcomes and achievements for the welfare of students.
Analisis Kebutuhan Media Pembelajaran Word Search Puzzle pada Materi AlKhabir Kelas VII MTs Hidayatul Muhajirin Palangkaraya
Authors: Safitri Suci Aulia , Maulana Ahmad
Published: November 2024

This research is to analyze the need for using Word Search Puzzle learning media in Al-Khabir material in class VII MTs Hidayatul Muhajirin Palangka Raya. The research uses a mixed method, combining quantitative and qualitative approaches, with data collected through questionnaires and interviews. The research results show that 79% of students have high interest in using Word Search Puzzle, while 21% are less interested. This media is effective in increasing students' motivation, involvement and understanding of the material being taught. Apart from that, Word Search Puzzle also stimulates critical thinking skills, accuracy and concentration. And as many as 59% of teachers only use media in the form of modules such as textbooks or worksheets, while the other 41% do not use technology-based media in learning. Thus, this research recommends the development of innovative learning media to increase student involvement in the teaching and learning process in accordance with educational needs in the digital era.
Pengaruh School Well Being terhadap Prestasi Belajar Siswa di SMA Negeri 3 Bukittinggi
Authors: Rahayu Dini , Afrida Yeni , Arjoni Arjoni , Hartati Sri
Published: November 2024

This research was motivated by the condition of condition of student well-being (school well-being) at SMA Negeri 3 Bukittinggi which includes four aspects includes four aspects: school facilities (having), student self-fulfillment (being), social relationships (loving), and health (health). The research aims to to determine the effect and level of influence of school well-being on student achievement. student learning achievement. Using an associative type quantitative approach, this research This study involved 149 respondents who were selected by proportional random sampling. The research instrument was a questionnaire, and data analysis used simple regression. regression. The results showed the average score of students' school well-being score of 126 (high) with a percentage of 84%, and learning achievement in the competent category (100%). competent category (100%). Hypothesis testing shows school well-being has a significant effect on learning achievement with a significance value of 0.000 (<0.05) and Fcount (16.461) > Ftable (3.91). The effect of school well-being on learning achievement is 10.1%, so it can be concluded that school well-being plays an important role in improving learning achievement. that student well-being plays an important role in improving learning achievement.
Buy Now, Think Later: Financial Literacy and Impulse Buying Behavior among College Students in City of Malolos
Authors:   Bulacan State University, City of Malolos, Bulacan, Philippines, Sarmiento Allen Grace M.
Published: November 2024

In today's generation, where purchasing is one click away, young Filipino adults seem to set aside the value of proper handling of money in order to possess products that catch their attention. Most of them buy luxuries rather than saving for the future and live in the "you only live once" philosophy. On the other hand, one way to develop wise spending behavior among young adults is to make them financially literate. Unfortunately, being financially literate is slightly seen among Filipino youths today. The main objective of this research was to examine the relationship between financial literacy and impulse buying behavior among college students at Bulacan State University. The study was anchored in Prospect Theory based on an individual's perceived gains and utility. Spearman correlation was employed to determine and analyze the results of 280 college students at Bulacan State University. The results revealed that the financial literacy of college students has a positive and significant relationship with impulse buying behavior. This implies that as their financial literacy increases, their impulse buying behavior increases. In conclusion, Bulacan State University college students value present choices and benefits more than the future.
Econometric evaluation of Economic freedom and Health outcomes in East African community
Authors:   Kenyatta University, Nairobi, Kenya., Wachira Margaret Wanjiru , Gachoki Charles Munene ,   Kenyatta University, Nairobi, Kenya.
Published: November 2024

Economic freedom encompasses a range of mechanisms that influence the health outcomes in economies worldwide. Decreasing the size of the government and implementing lower taxes, both of which are elements of economic freedom, could potentially lead to a reduction in government spending on healthcare, so putting health outcomes at risk. Despite improvements in health outcomes in East African countries like Kenya, Uganda, Tanzania, and Rwanda, including decreased newborn death rates and increased life expectancy, the East African Community still falls behind its Asian counterparts. This research aims to ascertain the connection between health outcomes and economic self-sufficiency in the East African Community. The study purpose was to look at the relationship between economic independence and both life expectancy and the rate of newborn mortality in the East African Community. The selected study design was descriptive, using secondary quantitative data obtained from world development indices. A variety of tests were performed and it was determined that fixed effects regression was suitable on the panel data generated from the 4 countries of East Africa between1997 to 2021. The study established that Carbon emissions have positive relationship with mortality rates per 1000 live births. Similarly, actions of government such as increase in consumption expenditure, gross domestic product percapita, labour force, trade all had significant p values at 0.05 level and therefore any increase in these variables result to minimal infant fatality rates and also increases probability of life expectancy. This study also confirmed that urbanization has no significant influence on life expectancy as well as mortality rates per 1000 lives.
Strategies For Strengthening Community Engagement (Civic Engangement) Tuban East Java In Building Ecological Citizenship By Mangrove Center Foundation
Authors: Dwi Wahyu Kartikasari  , Fitria Anjar Sari  , Djoko Apriono  , Yudi Supijanto  , Suttrisno Suttrisno
Published: November 2024

The purpose of this study was to determine the strategy of the mangrove center Foundation in strengthening Tuban community involvement into ecological citizenship. This research is based on the issue of environmental damage that is increasing every year, as well as the handling of environmental damage related to the government, related institutions, and the community. This study uses qualitative methods with a case study approach. The results found from this study is the role of the Mangrove Center as part of the civic community in combating environmental damage through strengthening environmental awareness in the community and related institutions. The participation starts from socialization, providing examples, and working together with the Environment Agency and local government agencies.
Reconstruction of Vygotsky's Sociocultural Theory of Thinking in Learning Arabic Language at Elementary School Level
Authors: Roihanah Zakiyah  , Resy Mulyani
Published: November 2024

Learning Arabic is one of the important subjects at the elementary level. Therefore, greater attention is needed in the goals, implementation, and evaluation of learning. In learning Arabic, interaction with the environment and cognitive roles are necessary so that students can comprehensively learn the language in terms of practice and theory. Through this interaction, students' cognitive abilities will develop. As mentioned in Vygotsky's theory, students' cognitive abilities develop as they interact with their environment.
The Crucial Significance of Regulatory Compliance in Business Operations and Supply Chain Management in the South-Western Region of Nigeria
Authors:   Faculty of Economics and Management Kampala International University Uganda, Uchechukwu Aleke Jude , Alum Benedict Nnachi ,   Department of Research Publication and Extension Kampala International University, Uganda
Published: November 2024

Ensuring adherence to regulations was of utmost importance for firms operating in southwestern Nigeria, especially when it comes to managing the supply chain. This essay examined the crucial importance of regulatory compliance in guaranteeing legal, moral, and environmentally responsible economic operations in the area. The text explored the intricacies of the regulatory environment, which includes federal, state, and municipal rules. It also emphasized the difficulties that companies had, such as limited resources, bureaucratic inefficiency, and frequent changes in regulations. Based on the analysis of the significance of regulatory compliance for risk management, business continuity, and stakeholder confidence, the paper presented findings on the need for proactive compliance methods and cooperative endeavours among stakeholders. Recommendations were given to improve adherence to regulations, which included strengthening the ability to comply, making changes to regulations, adopting new technologies, collaborating between the public and commercial sectors, including stakeholders, implementing incentive systems, and continuously monitoring and evaluating the situation. To cultivate a culture of adherence, encourage moral behaviour, and stimulate sustainable progress in southwestern Nigeria, companies and regulators might adopt these suggestions.

Keywords: Regulatory compliance, Business operations, Supply chain management, Risk management, Stakeholder involvement.
Combating Malaria with Plant-Based Antimalarials: A Comparative Study
Authors:   Faculty of Pharmacy Kampala International University Uganda, Edgar Muhindo
Published: November 2024

Malaria remains a leading global health threat, especially in low-income regions such as Sub-Saharan Africa, where traditional antimalarial treatments face increasing challenges due to drug resistance. Artemisinin-based combination therapies (ACTs) have long been the primary frontline treatment; however, escalating resistance in Plasmodium species has prompted researchers to investigate alternative solutions, including plant-derived antimalarials. This study examines the efficacy and safety of plant-based antimalarial compounds, particularly Artemisia annua, compared to synthetic drugs, considering traditional knowledge and contemporary pharmacological perspectives. Plant-based compounds may offer unique advantages, such as multi-target mechanisms and reduced side effects, presenting them as viable candidates for future malaria treatments. This study highlights the potential of plant-based antimalarials as sustainable and accessible alternatives, emphasizing the need for further research into clinical efficacy, safety pharmacology, and collaborative efforts with traditional practitioners.

Keywords: Malaria, Antimalarial resistance, Plant-based antimalarials, Artemisia annua, Artemisinin-based combination therapy (ACT), Traditional medicine.
Impact of Stigma on HIV Treatment and Care among American Patients: A Comprehensive Review
Authors:   Faculty of Pharmacy Kampala International University Uganda, Mahinda Masika Anna
Published: November 2024

Stigma surrounding HIV was a significant barrier to effective treatment and care for individuals living with the virus in the United States. This comprehensive review examined the various dimensions of stigmasocial, internalized, and structuraland their detrimental effects on access to healthcare, treatment adherence, and overall mental health outcomes for American patients. To write this review, a systematic literature search across multiple databases were utilized to gather relevant studies and reports on HIV-related stigma and its impact on treatment and care. The review highlighted how stigma contributed to delayed care-seeking behaviors, non-disclosure of HIV status, and increased psychological distress, ultimately compromising health outcomes. It also identified facilitators that can help mitigate stigma, including community support groups, peer advocacy, educational initiatives, and integrated healthcare services. By synthesizing existing literature and evidence-based interventions, this review underscored the urgent need for comprehensive strategies aimed at reducing stigma and promoting a supportive environment for individuals living with HIV.

Keywords: Stigma, HIV, Treatment Adherence, Mental Health, Healthcare Access.
Targeting Androgen Receptor Variants in Castration-Resistant Prostate Cancer (CRPC): A Comprehensive Review
Authors:   Faculty of Pharmacy Kampala International University Uganda, Latricia Mercy
Published: November 2024

Castration-resistant prostate cancer (CRPC) represents a significant clinical challenge due to its aggressive progression despite androgen deprivation therapy (ADT). One of the key mechanisms driving CRPC is the emergence of androgen receptor (AR) variants (AR-Vs), particularly AR-V7, which remain active in low-androgen environments and promote tumor survival and proliferation. These AR-Vs lack the ligand-binding domain but retain the transcriptionally active N-terminal domain, making them resistant to conventional AR-targeted therapies. This review comprehensively explores the biology of AR-Vs, their role in CRPC progression, and recent advancements in targeting these variants. Emerging therapeutic strategies include AR N-terminal domain inhibitors, spliceosome-targeting therapies, and novel degraders that specifically address AR-Vs. The review also discusses potential biomarkers for AR-V-driven CRPC and highlights the challenges in translating preclinical findings into effective clinical interventions. Targeting AR-Vs offers a promising avenue for overcoming resistance in CRPC, providing new hope for patients with advanced disease.

Keywords: Castration-resistant prostate cancer, androgen receptor variants, AR-V7, androgen deprivation therapy, N-terminal domain inhibitors, spliceosome-targeting therapies
Bioengineered Skin for Burn Victims: Advances and Challenges
Authors:   Faculty of Pharmacy Kampala International University Uganda, Fortunate Abaho Areeba
Published: November 2024

Burn injuries impact millions worldwide, causing significant physical and psychological burdens due to scarring, limited function, and the risk of infection. Traditional skin grafting techniques have limitations in restoring full skin function and appearance, creating an urgent need for improved treatment methods. Bioengineered skin offers a promising alternative, utilizing tissue engineering, stem cell technology, and advanced scaffold materials to support skin regeneration and healing. This paper discusses the evolution of skin grafting, highlights current bioengineering approaches, including cell and scaffold innovations, and explores clinical applications of bioengineered skin substitutes. Although advances have been promising, challenges remain in material selection, cellular integration, and large-scale clinical application. Future success will hinge on interdisciplinary collaboration, regulatory support, and continuous research to overcome barriers and improve outcomes for burn patients.

Keywords: Bioengineered skin, Burn treatment, Skin regeneration, Tissue engineering, Stem cells.
The golden discovery of camelina sativa: a pivotal study of ıts unique components and its multiple uses in various applications in science and industry
Authors: Mahious Rayane , Halvacı Ebru , Aygün Ayşenur , Şen Fatih
Published: November 2024

The increase in the global population causes a rapid increase in environmental pollution and energy consumption. Countries aim to increase the use of alternative energy sources as fossil fuels are limited and not universally accessible when generating their energy. In addition, research in the biofuels industry is expanding to include research on the use of vegetable oils as fuel. Camelina serves as a perfect illustration because of its abundant nutrients. Camelina, known as Camelina sativa L. Crantz, is a member of the cruciferous family and has been grown for its valuable characteristics for many centuries. Camelina seeds contain high levels of both protein (27-32%) and oil (38-43%). Camelina oil is rich in various components like phytosterols, phenolic compounds, tocopherols, and fatty acids, with omega-3 and omega-6 being the key ones. In the field of agriculture, growing this crop is appealing because it has a brief growing period and requires little water and fertilizers. Camelina is well-suited for arid regions because of its ability to withstand dry conditions and low temperatures. Due to its economic importance and easy cultivation in recent years, Camelina has many applications such as biofuel, food, agriculture, animal feed, cosmetics, and medicine. For example, Camelina is grown in the United States and Europe as a valuable crop that can be used to replace existing fuels. Future research aims to enhance its agricultural characteristics and view it as a substitute for existing fuels. This review focuses on the camelina plant, its oil, components, and properties, as well as its use in areas such as food, biofuels, animal feed, and agrochemicals.
Comparison of Optical Properties in Single-Shade and Multi-Shade Composite Resins
Authors: Yang Minyoung , Kim Hyuntae , Song Ji-Soo , Shin Teo Jeon , Hyun Hong-Keun , Kim Young-Jae , Kim Jung-Wook
Published: November 2024

This study aimed to evaluate the differences in optical properties, such as color and translucency, between single-shade composite resins (Omnichroma) and multi-shade composite resins (Filtek Z350XT). Furthermore, the study assessed the influence of the surrounding structure’s shades on the shade matching of Omnichroma. Two types of disc-shaped specimens were prepared: Single specimen (diameter, 8.0 mm; thickness, 1.0 and 2.0 mm), consisting of either Omnichroma or Filtek Z350XT in the A1B, A2B, and A3B shades, and dual specimen (diameter, 8.0 mm; thickness, 2.0 mm), featuring a bottom layer (diameter, 8.0 mm; thickness, 1.0 mm) of Filtek Z350XT in the A1B, A2B, and A3B shades, and a top layer (diameter, 8.0 mm; thickness, 1.0 mm) filled with Omnichroma. Commission Internationale d’Eclairage L*a*b* color measurements and calculations for color differences (ΔE*ab) and translucency parameters (TP) of each specimen were performed. Omnichroma exhibited a lighter, more greenish, and blueish color compared to the Filtek Z350XT in A1B, A2B, and A3B shades. With increased thickness, Omnichroma became more yellowish, whereas Filtek Z350XT became less yellowish. Additionally, when Omnichroma was applied over Filtek Z350XT in dual specimens, the yellowness increased further beyond Omnichroma’s original yellowness level. Consequently, Omnichroma achieved clinically acceptable shade matching, especially in the A3 shade, because it aligns well with the original high yellowness of the A3 shade. Additionally, Omnichroma’s superior shade-matching ability was attributed to its higher translucency compared to Filtek Z350XT. Therefore, Omnichroma might be considered useful in pediatric dentistry by simplifying the shade selection process.
Pháp luật tuyển dụng công chức ở Việt Nam hiện nay
Authors: Đặng Thị Phượng
Published: November 2024

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Mối quan hệ giữa toàn cầu hóa và chủ nghĩa dân tộc trong giai đoạn hiện nay
Authors: Ngô Thị Huyền Trang
Published: November 2024

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Tăng cường quản lý nhà nước về công tác phòng, chống tội phạm vùng Đông Nam Bộ
Authors: Nguyễn Thị Thanh Thùy
Published: November 2024

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Số hóa tài liệu lưu trữ trong bối cảnh chuyển đổi số
Authors: Nguyễn Kim Dung  , Trần Thị Hiền
Published: November 2024

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Magnitude of Episiotomy Practice and Associated Factors among Mothers Who Give Birth in Hospital
Authors: Fantaye Tinsae , Dana Tadele , Yohannes Dereje , Admasu Amare
Published: November 2024

Episiotomy is the most common obstetric procedure, performed when the clinical circumstances place the mothers at a high risk of high-degree laceration. However, episiotomy should be done with judicious indication to lower perineal laceration with fewer complications. Despite its adverse eﬀects, the magnitude of episiotomy is increasing due to diﬀerent factors. The study aimed assesses the magnitude of Episiotomy practice and associated factors among mothers who give birth in Wolaita Sodo University Comprehensive Specialized Hospital 2022.
Institution based cross-sectional study design was conducted from September-1 October 30/ 2021. The total sample size of the study was 369. A systematic random sampling technique was used to select study participants. Descriptive statistics, bivariate and multivariable logistic regression analyses was performed to identify factors associated with the magnitude of episiotomy. Adjusted odds ratio with 95% CI should be reported mean while the level of statistical signiﬁcance variables at P-value ≤ 0.05. The results were presented with text, table and figures.
The magnitude of episiotomy practice is 48.2 % [95% CI (43.1, 53.4)]. Spontaneous onset of labor [AOR= 2.85(1.55,5.23)], prolonged 2nd stage of labor (>30 minutes) AOR=2.71(1.73,4.25)] in comparison with duration of 2nd stage of labor <30 minutes, non-vertex presentation [AOR= 0.23(0.07,0.73)], use of oxytocin [AOR= 1.86(1.15,3.00)] deliveries attended by obstetricians [AOR=3.09(1.33,7.18)] were found to be associated with exposure to episiotomy among mothers. The overall rate of episiotomy in this study was much higher than the standards recommended by the World Health Organization (WHO). Factors associated with episiotomy practice were spontaneous onset of labor, prolonged second stage of labor, fetal presentation, use of oxytocin and obstetrician. Therefore, to reduce unnecessary rate of episiotomy practice, should be give adequate training to HCWs.
Toll-like Receptors and Artificial Intelligence in Fertility Management: Clinical Research Snapshot in United States of America and Asia-Pacific India Genetic Landscapes
Authors: Pandey Saumya
Published: November 2024

Dissecting the intricate “maternal-fetal immune cross-talks” in the complex etiopathogenesis of reproductive endocrinology disorders primarily Mycobacterium tuberculi mediated female infertility and Chlamydia trachomatis mediated male infertility in genetically disparate susceptible “at-risk” cohorts of heterogeneous population-pools by amalgamating precision-based therapeutic targeting of Ceramide-Wnt/Frizzled-Toll like receptors-autophagy biochemical/metabolic signaling cascades with Artificial Intelligence (AI) offers fascinating healthcare management avenues in timeline-driven pragmatic, evidence-based predictive biomarker development in the Covid-19/Omicron vaccination era.
Textbook Presentation of Cannonball Pulmonary Metastases
Authors: Sharma Vishnu , Bagrodia Vansh
Published: November 2024

This case report presents a late sixties male patient who arrived with massive hemoptysis and breathing difficulties. Shock symptoms were evident, alongside distinct cannonball-like lung lesions on X-ray, prompting consideration of metastases. Clinical evaluation and attendant history suggested renal cell carcinoma (RCC) as an underlying cause. Despite swift intervention, the patient deteriorated rapidly, succumbing to recurring hemoptysis within hours. This report underscores the challenging diagnosis and management of aggressive metastatic RCC, particularly underscored by the unique X-ray presentation, emphasizing the significance of acute medical presentations.
Zinc(Ⅱ) Mediated Suppressive Prostate Cancer for Progression with Stages 1～3, and Zinc Ions-Coordinated Prostate Anti-Cancer Molecular Mechanism
Authors: Ishida Tsuneo
Published: November 2024

Zinc(Ⅱ) induced prostate cancer (PCa) suppressive development Stage 1, Stage 2, and Stage 3 have been investigated, the PCa anticancer activity and apoptosis molecular mechanism is subsequently elucidated on the basis of anti-cancer activities of Zn-CysHis Ligands complexes formed by zinc ions-coordinated tetrahedral geometry.
For the PCa Stage 1, zinc can prevent PCa progressing, inhibit PCa cell growth and proliferation, and lead to apoptogenesis that zinc concentration (100～1000 ng/mL) can prevent the PCa progressing, ZnCl2(0～300 μM) regulates as a negative growth for PCa cells, 10, 20 mg/kg ZnCl2-treated prostate cancer tumors can be diminished, and zinc (15 μM) increases the Bax-associated mitochondrial pore Bax/Bcl-2 ratio, leading to apoptotic effect.
For PCa Stage 2, zinc suppresses the progression of PCa by proliferation, migration, and invasiveness that zinc is confirmed to function as a tumor suppressor in PCa cells, in which zinc, zinc transporters, and zinc and ZRT- and Irt-like proteins1 (ZIP1) can suppress tumor growth, invasive and migratory tumor malignant cell, and regional lymph nodes in PCa cancer.
For PCa Stage 3, metastatic prostate cancer is composed of proliferation, neovascularization, extravasation, and bone or bone marrow metastasis that MAZ regulates PCa bone metastasis, intercellular zinc levels inhibit metastatic and angiogenic malignant cells, and ZMYND8 inhibits tumor angiogenesis. 　　
Zinc induced ROS generation in PCa cell is involved that ROS-mediated oxidative stress on prostate cancer can be modulated by rich antioxidants and accumulated zinc, leading to apoptotic tumor cells.
Zinc coordinated anticancer and apoptosis molecular mechanism in PCa cells is involved that Zn2+ ions having Zn2+ ions-centered Zn-CysHis Ligands complexes with tetrahedral geometry bind with each other PCa stages tumor proteins, causing Zn2+ ions-several protein complexes formed and apoptosis of PCa cells, leading the Zn-CysHis Ligands complexes to molecular anti-cancer activities and apoptosis for prostate cancer tumor cells.
Neuroimages: Ischemic Zone and Tubercular Zone-Two Faces of the Same Coin
Authors: Kaushal Himanshu , Goyal Gourav , Bhatt Rajat , Kain Reva
Published: November 2024

Central nervous system tuberculosis (CNS TB) is one of the extrapulmonary manifestations of tuberculosis which poses a great burden in the developing world in the form of high morbidity and mortality if not recognized and treated timely. Vascular complications in infectious diseases including tuberculosis (TB) are of paramount importance as they mimic atherosclerotic lesions of small as well as large vessels. Moreover, mortality in patients with CNS TB increases to threefold if there are vascular complications in the form of stroke.
A Bibliometric Analysis of CEM Cement: Tracing Trends and Impact in Dental Research
Authors: Asgary Saeed
Published: November 2024

The rapid development of dental biomaterials necessitates a comprehensive understanding of current trends and their impact. Conducting a bibliometric analysis becomes crucial to identify key research directions, influential researchers, and significant contributions in this dynamic field. Such insights will guide evidence-based decisions, foster collaborations, and shape the future of dental biomaterials for improved patient care and clinical outcomes. This study aimed to conduct a comprehensive bibliometric analysis of calcium-enriched mixture (CEM) cement as an endodontic biomaterial in dental literature. A comprehensive search of the Scopus database was performed using relevant keywords. The data collection period extended from 2010-2023. The collated data underwent thorough analysis to delineate publication trends, source distribution, document types, subject areas, geographical distribution, authorship, keywords, and citation impact associated with CEM cement research. The analysis demonstrated a marked rise in scholarly interest in CEM cement since 2010, with a peak noted in 2016. The "Iranian Endodontic Journal" surfaced as a significant platform for CEM cement research. Original research articles constituted the majority of the documents, emphasizing the value of primary research in this field. Although dentistry was the prevalent subject area, contributions were also discernible in fields such as medicine/materials science. Geographically, Iran led in terms of research contributions, followed by the USA. Prominent researchers' participation further underlined the scientific influence and specialized knowledge in this field. Keyword analysis provided insights into prevailing research themes, including endodontics and material properties. This analysis yielded valuable insights into the evolving research landscape of CEM cement in dental literature; it can inform/guide future research directions/collaborations in dental biomaterials science.
Treatment outcome of chronic hepatitis C virus infected patients and experience with direct acting agents from Ethiopia: Retrospective study
Authors: Habtamu Yonatan , Demissie Zekewos , Demissie Zekewos , Berhe Rezene
Published: November 2024

Background: Hepatitis C virus is a multisystem disease with substantial morbidity and mortality. The genotypic distribution of the virus and treatment outcome with direct acting agents are variable geographically.
Method: A retrospective study was conducted to assess treatment outcome of Hepatitis C infected patients treated with direct agents at Tikur Anbessa Specialized Hospital and Adera Gastrointestinal Specialty clinic from January 2018 to January 2020. A total of 84 patients were included. The data was analyzed by using the latest SPSS version 26.
Result: A total of 84 patients were included with a mean age of 49±10.6 years. Diabetes and Hypertension were the commonest comorbidities. Majority of the patients were found to be infected with genotype. Seventy-seven (91.7%) patients were treatment naïve and 34(40.5%) had evidence of liver cirrhosis. Overall sustained virologic response at 12 weeks was achieved in 76 (90.5%) patients. The virologic response occurred in 93.5% non-cirrhotic and 83.5% of cirrhotic patients. The presence of fibrosis was found to be associated with non-response to therapy. Fatigue and nausea were the commonest side effects and life-threatening complications were not reported.
Conclusion: The current study found treatment of chronic HCV infected Ethiopian patients with DAAs resulted in 90.5 % SVR12 rate with minimal safety concerns. The study also found, non-cirrhotic patients achieved higher rates SVR12 than cirrhotic patients and high APRI score negatively affect treatment outcome.
The Activity of the Proapoptotic Protein Caspase-3 Changes in Glial Cells of the Peritumoral Zone of Secondary Brain Tumors, and its Relationship with Intraoperative Photodynamic Therapy
Authors: Sitovskaya Darya , Makshakova Darya , Sokolova Tatyana , Kukanov Konstantin , Nechaeva Anastasiia , Zabrodskaya Yulia
Published: November 2024

The metastasis of solid tumors to the central nervous system is a pressing issue due to its association with poor prognosis and low survival rates. Recent studies have shown that glial cells can promote metastasis even before the appearance of tumor cells, highlighting the need for new treatment methods. One potential method is intraoperative photodynamic therapy (PDT), which has been shown to improve the success of neuro-oncological surgeries and local control. However, the role of glial cell apoptosis in the development of brain metastases and the impact of PDT on apoptosis are still unclear. In this study, biopsy samples were collected from 25 patients undergoing surgery at the Polenov Neurosurgical Institute, including 16 women and 9 men with an average age of 63.04 years (ranging from 39 to 78 years). PDT was administered using the drug "Photoditazine" at a dosage of 1 mg per 1 kg of body weight. Histological sections stained with hematoxylin and eosin, as well as immunohistochemical (IHC) reactions with a rabbit polyclonal antibody to active caspase-3, were analyzed in the pathology department. The results showed that in the peritumoral zone of metastases, oligodendrocytes were the main cells undergoing apoptotic death, and PDT also induced apoptosis in astrocytes. The use of PDT significantly increased apoptosis in brain tissue (p<0.05). These findings suggest that targeting gliocyte apoptosis and caspase-dependent apoptosis mechanisms may be a potential therapeutic approach in the comprehensive treatment of metastatic carcinomas.
Violence against Housemaids and associated factors in Jimma Town, Southwest Ethiopia, 2023: A Mixed-Method Study
Authors: Aynalem Hiwot , Abdulahi Misra , Diribsa Tujuba , Tadele Esayas
Published: November 2024

Background: Violence against women is a pervasive public health problem that remains hidden and largely underreported. Although all women are vulnerable to violence, the probability of experiencing violence against housemaids seems to be particularly high. However, evidence on the prevalence of violence against housemaids and associated factors is scarce.
Objectives: To assess the prevalence and factors associated with violence against housemaids in Jimma town, southwestern Ethiopia, in 2023.
Methods: Parallel sampling was used in a community-based mixed-methods study of 422 housemaids living in Jimma town. Simple random sampling was used to select participants. To collect the data, a questionnaire administered during a pretested structured interview was used. Qualitative data from fifteen in-depth interviews were collected using a semi-structured questionnaire. Quantitative data were collected using an open data kit and then exported to SPSS version 26. Bivariate analysis was performed to select candidate variables with P values <0.25. Then, multivariable logistic regression was used to determine factors associated with P values less than 0.05 with their respective AORs and 95% CIs. Finally, a report was presented. Thematic analysis was performed using ATLASti software after the audio recordings were transcribed.
Results: The work lifetime prevalence of violence against housemaids was 61.7%. Violence against housemaids during their work lifetime was associated with having no formal education (AOR=3.7; 95% CI: 1.22-11.33), having a duration of work greater than four years (AOR=2.6; 95% CI:1.44-4.99), having two to four durations of work (AOR=2.4; 95% CI:1.29-4.61), having a job by broker (AOR=2.8; 95% CI:1.72-4.62), lacking a specific task (AOR=1.8: 95% CI:1.07-2.90), no social support (AOR=4.5; 95% CI:1.56-12.89), and having more than six families (AOR=5.4; 95% CI,2.19-13.49). The qualitative findings also revealed that there was no legal work agreement.
Conclusion and Recommendation: The prevalence of violence against housemaids was relatively high. Over one-third (46.7%) of them experienced at least one incident of physical, psychological, or sexual violence. Educational status, duration of work, having a job with a broker, lack of specific tasks, social support, and family size were factors associated with violence against housemaids. The government established an appropriate strategy for prevention, which is essential for revising the existing laws, articulating the new laws, and ratifying Convention 189.
Correlación entre sistema de costos por procesos y la rentabilidad en las asociaciones artesanales textiles
Authors: Huarcaya Taype Rosaura , Lozano Núñez Carlos , Lozano Núñez Pedro Demetrio , Picoy Gonzales Juan Antonio , Ramos Serrano Rúsbel Freddy
Published: November 2024

The process costing system allows for understanding the distribution of each activity in terms of costs, making it a key element for decision-making. This research aimed to determine the relationship between the process costing system and the profitability of artisanal textile associations in the Paucará District, Peru. Due to its characteristics, the research corresponds to a non-experimental design with a cross-sectional, descriptive-correlational approach. To explain the study problem, both bibliographic and field research were conducted, utilizing theoretical, empirical, and statistical methods. The analysis was performed using descriptive and inferential statistics; the Spearman correlation coefficient was found to be 0.480 with a 95% confidence level. The proposed results highlight a consistent positive and direct relationship between the two factors under study, indicating that having a process costing system
Gestión de riesgos financieros y su relación con la triple restricción en una constructora
Authors: Quispe-Ponce Henry Eloy
Published: November 2024

Risk management in construction projects is essential to anticipate problems, optimize resources and ensure the fulfillment of objectives. This article aims to determine the relationship between financial risk management and the triple constraint in residents of the construction company in Lima, Peru. A non-experimental, descriptive correlational design with a quantitative approach was used. The sample included 44 civil engineers; data were collected through direct observation and a questionnaire, using Monte Carlo simulations to identify risk scenarios. The results show a strong positive relationship between the variables studied, evidencing that adequate management of market, operational and legal risks optimizes scope, time and cost. It is concluded that integrating effective risk management practices is essential to improve performance and ensure the long-term sustainability of projects.
Reglamentación e infraestructura para que el Puerto del Callao sea Hub en la Costa Oeste Sudamericana
Authors: Morán Relaiza Saúl
Published: November 2024

An appropriate regulation and cutting-edge infrastructure are essential for the Port of Callao to position itself as a hub on the west coast of South America. This research aims to determine whether state regulation has the adequate level of sufficiency for the Port of Callao to meet the conditions of a HUB port on the west coast of South America by the year 2030. The research was conducted using an analytical design and a quantitative approach. The sample consisted of nineteen officials. The main results highlight that state regulation has a positive impact on the development of the necessary infrastructure for the port to meet hub requirements. It is concluded that the majority of respondents perceive state regulation as good, reflecting a high level of satisfaction with the reforms implemented at the Port of Callao as a hub.
Apropiación de Instagram por las cadenas comerciales Sweet & Coffee y Juan Valdez en Ecuador
Authors: Ruiz Quezada Karla Melissa , Barzola Jaya Daniel Washington , Alcívar Cabada Ronald Ricky
Published: November 2024

Instagram is key to business growth, builds a visual brand, drives sales and measures the impact of digital marketing strategies. The objective of this research was to analyze the appropriation of the use of this social network by the Ecuadorian commercial chains Sweet & Coffee and Juan Valdez Café. The study is cross-sectional, descriptive and non-experimental, the sample was 384 users. The results of the metrics reveal that, although Juan Valdez Café has more followers, Sweet & Coffee surpasses it in interactions, engagement rate, 0.48% and performance, 11.0%. The analysis of the means reveals a relevant difference in the level of performance of the two profiles. Both companies use a variety of images, videos and carousels. These findings highlight the need to adapt social media marketing strategies to improve customer interaction and satisfaction, with dynamic and attractive content that connects with consumers.
NÂNG CAO HIỆU QUẢ TỔ CHỨC HOẠT ĐỘNG TỰ HỌC CHO SINH VIÊN NGÀNH GIÁO DỤC TIỂU HỌC TRƯỜNG ĐẠI HỌC HÙNG VƯƠNG
Authors: Nguyễn Xuân Huy  , Bùi Thị Loan  , Dương Thị Bích Liên
Published: November 2024

Tổ chức hoạt động tự học hiệu quả không chỉ quyết định kết quả học tập của sinh viên trong những năm tháng đào tạo tại trường đại học mà còn có ảnh hưởng lâu dài đến sự phát triển nghề nghiệp suốt đời của các em. Bài báo sử dụng phối hợp nhiều phương pháp nghiên cứu: phân tích, tổng hợp lý thuyết, phân loại tài liệu, văn bản, phỏng vấn, xin ý kiến chuyên gia, điều tra, quan sát... Trên cơ sở đánh giá kết quả thực trạng tổ chức hoạt động tự học cho sinh viên khoa Giáo dục Tiểu học, Trường Đại học Hùng Vương, bài báo đề xuất 3 biện pháp nâng cao tính tích cực, chủ động và sáng tạo trong việc tổ chức hoạt động tự học cho SV: (1) Hướng dẫn SV lập kế hoạch tự học một cách khoa học; (2) Tạo môi trường học tập thuận lợi cho sinh viên (3) Tổ chức và tạo điều kiện để SV làm việc theo nhóm kết hợp với thảo luận toàn lớp. Ngoài ra, còn 1 số biện pháp: Giảng viên lập hồ sơ tổ chức hoạt động tự học của sinh viên; Tổ chức các hoạt động nghề nghiệp; Xây dựng câu lạc bộ học tập cho sinh viên; Tạo điều kiện điều kiện, hoàn thiện phương tiện bảo đảm hoạt động tự học của sinh viên.