bluuebunny/crossref_metadata_2025 huggingface dataset:
The Restriction–Modification Systems of Clostridium carboxidivorans P7
Authors: Kottenhahn Patrick , Philipps Gabriele , Bunk Boyke , Spröer Cathrin , Jennewein Stefan
Published: December 2023

Clostridium carboxidivorans P7 (DSM 15243) is a bacterium that converts syngas (a mixture of CO, H2, and CO2) into hexanol. An optimized and scaled-up industrial process could therefore provide a renewable source of fuels and chemicals while consuming industry waste gases. However, the genetic engineering of this bacterium is hindered by its multiple restriction–modification (RM) systems: the genome of C. carboxidivorans encodes at least ten restriction enzymes and eight methyltransferases (MTases). To gain insight into the complex RM systems of C. carboxidivorans, we analyzed genomic methylation patterns using single-molecule real-time (SMRT) sequencing and bisulfite sequencing. We identified six methylated sequence motifs. To match the methylation sites to the predicted MTases of C. carboxidivorans, we expressed them individually in Escherichia coli for functional characterization. Recognition motifs were identified for all three Type I MTases (CAYNNNNNCTGC/GCAGNNNNNRTG, CCANNNNNNNNTCG/CGANNNNNNNNTGG and GCANNNNNNNTNNCG/CGNNANNNNNNNTGC), two Type II MTases (GATAAT and CRAAAAR), and a single Type III MTase (GAAAT). However, no methylated recognition motif was found for one of the three Type II enzymes. One recognition motif that was methylated in C. carboxidivorans but not in E. coli (AGAAGC) was matched to the remaining Type III MTase through a process of elimination. Understanding these enzymes and the corresponding recognition sites will facilitate the development of genetic tools for C. carboxidivorans that can accelerate the industrial exploitation of this strain.
The Pneumococcal Protein SufC Binds to Host Plasminogen and Promotes Its Conversion into Plasmin
Authors: Yasui Yoshihito , Hirayama Satoru , Hiyoshi Takumi , Isono Toshihito , Domon Hisanori , Maekawa Tomoki , Tabeta Koichi , Terao Yutaka
Published: December 2023

Streptococcus pneumoniae causes otitis media, sinusitis, and serious diseases such as pneumonia and bacteremia. However, the in vivo dynamics of S. pneumoniae infections and disease severity are not fully understood. In this study, we investigated pneumococcal proteins detected in the bronchoalveolar lavage fluid of an S. pneumoniae-infected mouse, which were assumed to be expressed during infection. Analysis of three proteins with unknown infection-related functions revealed that recombinant Fe-S cluster assembly ATP-binding protein (SufC) binds to the host plasminogen and promotes its conversion into plasmin. SufC was detected in the bacterial cell-surface protein fraction, but it had no extracellular secretory signal. This study suggests that S. pneumoniae releases SufC extracellularly through LytA-dependent autolysis, binding to the bacterial cell surface and host plasminogen and promoting its conversion into plasmin. The recruitment of plasmin by S. pneumoniae is considered useful for bacterial survival and spread, and SufC is suggested to facilitate this process.
Medicinal Herbs: Promising Immunomodulators for the Treatment of Infectious Diseases
Authors: Alanazi Hamad H. , Elasbali Abdelbaset Mohamed , Alanazi Maged K. , El Azab Eman Fawzy
Published: December 2023

Humans are constantly at high risk of emerging pandemics caused by viral and bacterial infections. The emergence of new pandemics is mainly caused by evolved viruses and bacteria that are highly resistant to existing medications. The rapid evolution of infectious agents demands the urgent investigation of new therapeutic strategies to prevent and treat these infections at an early stage. One of these therapeutic strategies includes the use of medicinal herbs for their antibacterial and antiviral properties. The use of herbal medicines as remedies is very ancient and has been employed for centuries. Many studies have confirmed the antimicrobial activities of herbs against various pathogens in vitro and in vivo. The therapeutic effect of medicinal herbs is mainly attributed to the natural bioactive molecules present in these plants such as alkaloids, flavonoids, and terpenoids. Different mechanisms have been proposed for how medicinal herbs enhance the immune system and combat pathogens. Such mechanisms include the disruption of bacterial cell membranes, suppression of protein synthesis, and limitation of pathogen replication through the inhibition of nucleic acid synthesis. Medicinal herbs have been shown to treat a number of infectious diseases by modulating the immune system’s components. For instance, many medicinal herbs alleviate inflammation by reducing pro-inflammatory cytokines (e.g., tumor necrosis factor-alpha (TNF-α), interleukin-1, IL-6) while promoting the production of anti-inflammatory cytokines (e.g., IL-10). Medicinal herbs also play a role in defense against viral and intracellular infections by enhancing the proliferation and functions of natural killer cells, T-helper-1 cells, and macrophages. In this review, we will explore the use of the most common herbs in preventing and treating infectious and non-infectious diseases. Using current and recently published studies, we focus on the immunomodulatory and therapeutic effects induced by medicinal herbs to enhance immune responses during diseases.
Rosmarinic Acid Elicits Calcium-Dependent and Sucrose-Sensitive Eryptosis and Hemolysis through p38 MAPK, CK1α, and PKC
Authors: Alghareeb Sumiah A. , Alfhili Mohammad A. , Alsughayyir Jawaher
Published: December 2023

Background: Rosmarinic acid (RA) possesses promising anticancer potential, but further development of chemotherapeutic agents is hindered by their toxicity to off-target tissue. In particular, chemotherapy-related anemia is a major obstacle in cancer therapy, which may be aggravated by hemolysis and eryptosis. This work presents a toxicity assessment of RA in human RBCs and explores associated molecular mechanisms. Methods: RBCs isolated from healthy donors were treated with anticancer concentrations of RA (10–800 μM) for 24 h at 37 °C, and hemolysis and related markers were photometrically measured. Flow cytometry was used to detect canonical markers of eryptosis, including phosphatidylserine (PS) exposure by annexin-V-FITC, intracellular Ca2+ by Fluo4/AM, cell size by FSC, and oxidative stress by H2DCFDA. Ions and pH were assessed by an ion-selective electrode, while B12 was detected by chemiluminescence. Results: RA elicited concentration-dependent hemolysis with AST and LDH release but rescued the cells from hypotonic lysis at sub-hemolytic concentrations. RA also significantly increased annexin-V-positive cells, which was ameliorated by extracellular Ca2+ removal and isosmotic sucrose. Furthermore, a significant increase in Fluo4-positive cells and B12 content and a decrease in FSC and extracellular pH with KCl efflux were noted upon RA treatment. Hemolysis was augmented by blocking KCl efflux and was blunted by ATP, SB203580, staurosporin, D4476, isosmotic urea, and PEG 8000. Conclusions: RA stimulates Ca2+-dependent and sucrose-sensitive hemolysis and eryptosis characterized by PS exposure, Ca2+ accumulation, loss of ionic regulation, and cell shrinkage. These toxic effects were mediated through energy deprivation, p38 MAPK, protein kinase C, and casein kinase 1α.
Preparation and Characterization of Zinc(II)-Based Lewis/Brønsted Acidic Deep Eutectic Solvents
Authors: Pelosi Chiara , Quaranta Aldo , Rollo Marco , Martinelli Elisa , Duce Celia , Ciancaleoni Gianluca , Bernazzani Luca
Published: December 2023

Lewis/Brønsted acidic deep eutectic solvents (LBDESs) are a recent class of solvents that combine the two types of acidity. In some cases, this synergy leads to enhanced catalytic properties for many reactions and applications. For this reason, it is important to discover more LBDESs. In this work, we prepared and characterized four different zinc(II)-based LBDESs, mixing ZnCl2 and various Brønsted acids: acetic, glycolic, levulinic, and formic acids. Apart from the latter, for which the corresponding DES is not thermally stable, the samples have been characterized in terms of density, viscosity, and conductivity. Notably, as zinc(II) is a diamagnetic metal, all of them are suitable for NMR spectroscopy, for example, for kinetic and mechanistic studies.
The Close Possibility of Time Travel
Authors: Effingham Nikk
Published: December 2023

This article discusses the possibility of some outlandish tropes from time travel fiction, such as people reversing in age as they time travel or the universe being destroyed because a time traveler kills their ancestor. First, I discuss what type of possibility we might have in mind, detailing ‘close possibility’ as one such candidate. Secondly, I argue that—with only little exception—these more outlandish tropes fail to be closely possible. Thirdly, I discuss whether these outlandish tropes may nevertheless be more broadly possible (e.g., metaphysically or logically possible), arguing that whether they are or not depends upon your favored metaphysics of the laws of nature.
Electromagnetically Induced Transparency Spectra of 6Li Rydberg Atoms
Authors: Wu Meimei , Bao Xin , Yu Shuxian , Yi Licheng , Ren Pingshuai , Deng Shujin , Wu Haibin
Published: December 2023

Rydberg atoms possess highly excited valence electrons that are far away from atomic cations. Compared with ground states, Rydberg states are excited states with a high principal quantum number n that exhibit large electric dipole moments and have a variety of applications in quantum information processing. In this communication, we report the measurement of the 6Li Rydberg excitation spectrum by ladder-type electromagnetically induced transparency (EIT) in a vapor cell. The 2p→ns/nd EIT spectra were recorded by sweeping the frequency of an ultraviolet Rydberg pumping laser while keeping the probing laser resonant to the 2s→2p transition. All lasers were locked on an ultrastable optical Fabry-Pérot cavity and measured by an optical frequency comb. Our results provide valuable information to precisely determine quantum defects and enable novel experiments with Rydberg-dressed ultracold Fermi gases.
Jump-Robust Realized-GARCH-MIDAS-X Estimators for Bitcoin and Ethereum Volatility Indices
Authors: Chevallier Julien , Sanhaji Bilel
Published: December 2023

In this paper, we conducted an empirical investigation of the realized volatility of cryptocurrencies using an econometric approach. This work’s two main characteristics are: (i) the realized volatility to be forecast filters jumps, and (ii) the benefit of using various historical/implied volatility indices from brokers as exogenous variables was explicitly considered. We feature a jump-robust extension of the REGARCH-MIDAS-X model incorporating realized beta GARCH processes and MIDAS filters with monthly, daily, and hourly components. First, we estimated six jump-robust estimators of realized volatility for Bitcoin and Ethereum that were retained as the dependent variable. Second, we inserted ten Bitcoin and Ethereum volatility indices gathered from various exchanges as an exogenous variable, each at a time. Third, we explored their forecasting ability based on the MSE and QLIKE statistics. Our sample spanned the period from May 2018 to January 2023. The main result featured the best predictors among the volatility indices for Bitcoin and Ethereum derived from 30-day implied volatility. The significance of the findings could mostly be attributable to the ability of our new model to incorporate financial and technological variables directly into the specification of the Bitcoin and Ethereum volatility dynamics.
A New and Little-Known Species of the Ground Beetle Genus Nebria Subgenus Falcinebria Ledoux and Roux, 2005 (Coleoptera: Carabidae) from Japan
Authors: Sasakawa Kôji
Published: December 2023

This paper presents additional notes on the carabid genus Nebria subgenus Falcinebria Ledoux and Roux, 2005 from Japan: a description of a new species Nebria suzukana sp. nov. from Mt. Gozaishodake; a new distribution and the southwesternmost collection record of Nebria furcata Sasakawa, 2020 from Mt. Uchimiyama; an additional record of Nebria kobushicola Sasakawa, 2023 from the Yatsugatake Mountains; and an additional record of an undetermined species from the Iide Mountains that was previously treated as Nebria taketoi Habu, 1962, with a note on its habitat. In addition, a key to the known species of Nebria (Falcinebria) from Honshu is provided.
Transnasal Endoscopic Pituitary Surgery—The Role of a CT Scan in Individual Tailoring of Posterior Septum Size Resection
Authors: Lubojacký Jakub , Čábalová Lenka , Mladoňová Michaela , Hránková Viktória , Krejčí Tomáš , Mičaník Jakub , Miklošová Maria , Ličev Lačezar , Komínek Pavel , Matoušek Petr
Published: December 2023

Objective: This study was designed to evaluate the possibility of predicting the minimum size of septal resection for safe tumor extraction in transnasal paraseptal pituitary adenoma resection from preoperative computed tomography scans. Methods: A retrospective CT scan analysis was performed on 20 patients who underwent endoscopic pituitary surgery at the University Hospital in Ostrava. Virtual insertion of the straight instrument into the sphenoid cavity was simulated using a CT scan. The minimum septal resection size was predicted and compared to various diameters in the nasal cavity. The results were then compared with cadaveric dissections, in which septal resections were performed at 1 cm and 2 cm distances from the anterior sphenoid wall. The association between cadaver dissections and CT scan results was studied. Results: A total of 20 patients who underwent endoscopic transnasal surgery for pituitary adenoma between the years 2020 and 2021 were enrolled in the study. The mean virtual posterior septal size resection needed to reach the medial edge of the ICA with the straight instrument, without infracturing the nasal septum, was 13.2 mm. In cadavers with a 1 cm posterior septal resection, the medial edge of the ICA was reached with the straight instrument. In 2 cm resections, it was possible to reach beyond the lateral edge of the ICA. Conclusion: There is no significant correlation between the minimum septal size resection and measured diameters in the nasal cavity. According to our study, a 1 cm resection is sufficient for a non-extended pituitary tumor extraction. More extensive septal resections allow for better maneuverability and overview in the surgical field.
Identification Method and Quantification Analysis of the Critical Aging Speed Interval for Battery Knee Points
Authors: Jia Xinyu , Zhang Caiping , Zhang Linjing , Zhang Weige , Xu Zhongling
Published: December 2023

The identification of knee points in lithium-ion (Li-ion) batteries is crucial for predicting the battery life, designing battery products, and managing battery health. Knee points (KPs) refer to the transition points in the aging speed and aging trajectory of Li-ion batteries. KPs can be identified using a wealth of aging data and various regression-based methods. However, KP identification relies on a large amount of aging data, which is exceedingly time-consuming and resource-intensive. To overcome this issue, we propose a novel method based on KP characteristics to identify the KPs and critical aging speed. Firstly, we extract the main aging trajectory using curve-fitting techniques. Secondly, we calculate the aging speed at each cycle to identify the KPs. We then explore the relationship between the KPs and cycle life and develop a knee point identification algorithm. The correlation coefficient between the KPs and cycle life provides a valuable indicator of the critical aging speed, enabling accurate identification of KPs. To validate our approach, we apply it to the Li(NiCoMn)O2, LiFePO4, and LiCoO2 cell datasets. Our results demonstrate a strong correlation between the KPs and cycle life for these battery types. By employing our proposed method, KPs can be identified for battery life prediction, product design, and health management. Moreover, we summarize a critical degradation speed of −0.03%/cycle can serve as an empirical threshold for warning against capacity diving and KPs. The statistical transition speed threshold can eliminate the dependence on extensive aging data throughout the entire battery’s lifecycle for identifying capacity knee points.
Self-improvement of the prospective specialist in the process of acquisition of civilizational heritage in tourism practices
Authors:   Department of Geography and Tourism FSBEI HE Moscow City Pedagogical University, LLC «NTL Group», SBCI Association of Cultural Centers of the Southern Administrative District, Moscow, Russian Federation, Kuznetsova N. V. , Arpentieva M. R. ,   International Academy of Education, Russian Academy of Natural Sciences, Russian Academy of Natural Sciences, Center for Psychological, Pedagogical, Medical and Social Сare «Assistance», Kaluga, Russian Federatio
Published: December 2023

The civilizational heritage of humanity as a whole and even of individual peoples has not yet become available to people in general: the problem lies not so much in people, but in the lack of practices and the very goal and understanding of the value of acquisition of the greatest possible wealth of the heritage of their people and other peoples (humanity) by each person. Science, art, religion, institutions of education and social assistance, etc. most often work in this direction fragmentarily, in isolation. Tourism can become an integrative practice. So far, it is still usually in the nature of one-time or periodic trips that do not have systematic goals and are not focused on the tasks of acquiring the civilizational heritage, a kind of «civilizational competence» of all people, however, this can be changed. Even now, many types of tourism offer an idea of tourism as a practice of (re) organization and improvement of human life, striving to expand their abilities and opportunities, their life world, self-improvement by familiarizing themselves with different facets of civilizational heritage. Self-improvement of a prospective specialist in the professional field can and should be combined with improvement in the spheres of personal and partner life, with familiarization with the achievements of civilization as such, in synchronous and diachronic changes (present, past, future, one’s own and another’s world/cultures).
Alimentación de pequeños rumiantes en pastoreo del trópico
Authors: Hernández Armando Pacheco , Hernández Diana Itzel Jerónimo
Published: December 2023

El presente artículo hace referencia a la alimentación de pequeños rumiantes en pastoreo del trópico, ovinos y caprinos tienen la habilidad de convertir carbohidratos y proteínas de origen vegetal en nutrientes disponibles para el uso humano, convirtiendo tierras que de otra manera serían inútiles, en productivas. Sin embargo, el cuidado apropiado de la tierra y los animales en pastoreo requiere de un buen entendimiento de nutrición rumiante. Los ovinos y caprinos utilizan los forrajes de una manera más eficiente que otros animales. Su alimentación debe alcanzar un buen balance de proteínas y de energía para permitir un nivel deseable de producción. Este balance se obtiene de las praderas de pastoreo, en el caso de que éstas no sean sobre pastoreadas. En el caso de cabras con altos requerimientos durante la lactancia, éstos pueden ser cubiertos con un suplemento de forraje fresco de alta calidad. En regiones con épocas críticas del año para producir forraje fresco (debido a heladas y sequía), será necesario prever esa deficiencia con forraje conservado. Las estrategias de alimentación deben utilizar todo lo que pueda ser consumido por los ovinos, como residuos de cosechas de cereales (pajas de arroz, trigo y cebada) y también de hortalizas.
Tapping Carbon Sequestration Potential of Blooming Macroalgae to Mitigate Climate Change
Authors: Zhang Yongyu , Liu Dong , Jiao Nianzhi
Published: December 2023

Macroalgal mariculture is gaining global attention to achieve carbon neutrality due to its important contribution to ocean carbon sequestration. However, some wild macroalgal species (e.g.,
Sargassum
and
Ulva prolifera
) exhibit strong environmental adaptability and can cause large-scale, recurrent blooms in global oceans, fueled by rising atmospheric CO
2
levels and coastal eutrophication. Notably, massive
Ulva prolifera
green tides have occurred annually in the Yellow Sea for the past 17 consecutive years. At the late blooming stage, millions of tons of
U. prolifera
naturally sink to the shallow seafloor. The subsequent intense microbial aerobic degradation of sinking macroalgae results in coastal hypoxia and acidification, with most of the macroalgal carbon returning to the atmosphere. Preventing or reducing the intense degradation of massive sinking
U. prolifera
could enable more macroalgal carbon storage in the ocean in the long term and alleviate the harmful effects of green tide. Thus, ecological disasters from macroalgal blooms may be transformed into useful natural platforms to increase ocean carbon sequestration. We propose an integrated strategy using environmentally friendly minerals (e.g., montmorillonite and calcium carbonate) and coagulants (e.g., polyaluminum chloride), along with natural algicidal bacteria or substances, to induce rapid flocculation and sedimentation of blooming macroalgae, reduce the degradation of sinking macroalgae and its negative environmental impacts, and minimize the generation of macroalgal propagules or seeds and the potential risk for future green tide outbreaks. This integrated approach is potentially a promising approach to tap the carbon sequestration potential of macroalgal blooms to mitigate climate change.
Modeling and Trajectory Tracking Control for a Novel Multinode Flexible Small-Body Lander Based on a Port-Hamilton Framework
Authors: Chai Jingxuan , Gong Youmin , Mei Jie , Wang Pengyu , Ma Guangfu
Published: December 2023

Small bodies have the characteristics of noncooperative, irregular gravity, and complex terrain on the surface, which cause difficulties in successful landing for conventional landers. In this paper, a multinode flexible lander is put forward to address the problem. The dynamics of this new lander are constructed based on the port-Hamilton framework. The trajectory-tracking formation controller for the lander is designed in a passive way. The proposed dynamics and controller are further validated through numerical simulations. This research presents a fresh concept that holds inspiration for future design involving small-body landers.
ГРИГОРІЙ СКОВОРОДА ТА ФАРАОН ЕХНАТОН, КІБЕРНЕТИКА, ЖІНКИ, БІБЛІЯ І БОГ
Authors: Рассоха Ігор
Published: December 2023

Григорій Савич Сковорода — один з найбільш шанованих в Україні
людей, недарма його зобразили на 500-гривневій купюрі. Проте вражає,
наскільки мало широкий загал наших навіть професійних істориків і філософів
реально знає про нього. Говорячи його ж словами, Сковорода — й досі як той
птах, що його ловлять та не можуть впіймати. Отже, не претендуючи на повне
осягнення величі цієї фігури, додам декілька сюжетів з тих, що вразили
особисто мене
КАЛІГРАФІЧНА СПАДЩИНА СКОВОРОДИ НА РОЗДОРІЖЖІ МІЖ ЄВРОПЕЙСЬКИМ, ГРЕЦЬКИМ ТА СЛОВ’ЯНСЬКИМ СКОРОПИСОМ XVIII СТОЛІТТЯ
Authors: Чекаль Олексій
Published: December 2023

Спадщина Григорія Сковороди досліджена майже з будь-якого ракурсу,
але дуже не часто хто вчені звертають увагу на рукописи українського
філософа з точки зору палеографії та естетики письма. Мабуть, найбільш
вичерпну бібліографію можна знайти у книзі Ушкалова «Григорій Сковорода:
семінарій» [21, 269 с.] та Академічному зібранню творів [16], однак і там літери
не стали предметом вивчення дослідників та пошуком місця каліграфії
Сковороди у сфері барокової української ідентичності. Тримаючи в руках
ці пожовклі папери, та розглядаючи як написані трактати та листи, не можна
не закохатися в неспішну ходу Сковородинівських літер, які відрізняються
від кореспонденції козацьких писарів та від канцелярського почерку
XIX сторіччя. Леонід Ушкалов зазначає що Сковорода здебільше записував
свої тексти літом в теплу пору року: «Філософ писав без жодного поспіху,
акуратно виводячи кожну літеру. Каліграфія в нього була просто чудова –
взірцевий український скоропис XVIII століття» [22, 269 с.] (рис. 1)
ФІЛОСОФІЯ ГРИГОРІЯ СКОВОРОДИ І СУЧАСНИЙ АКСІОЛОГІЧНИЙ ДИСКУРС
Authors: Бережна Світлана
Published: December 2023

Сучасне українське суспільство розвивається у відповідності до тих
ціннісних пріоритетів, які оформилися згідно з існуючими традиціями,
нормами, переконаннями, визначилися протягом століть та витримали
верифікацію. Саме тому, у даному розділі основний акцент робиться
навиявленні ціннісних орієнтацій, мотивації та цільових орієнтирівсучасної
української людини крізь аксіологічну призму філософсько-антропологічного
вчення Г. Сковороди. Багатоаспектність філософії серця видатного українського
просвітника є етико-аксіологічним орієнтиром для поглибленої рефлексії
дискурсу гідності в суспільстві, що відстоює своє право на незалежність.
Сучасні події в Україні продемонстрували, що українці готові боротись
та йти до кінця у боротьбі за власні переконання. У той же час, дуже часто
уявлення українців про європейські цінності містять стереотипи, хибні
переконання, що були сформовані пропагандою і маніпуляцією з боку тих
чи інших політичних сил.
СОЦІАЛЬНЕ ВИХОВАННЯ СТУДЕНТСЬКОЇ МОЛОДІ НА ЗАСАДАХ СВІТОГЛЯДНИХ ІДЕЙ Г.СКОВОРОДИ В УМОВАХ ЗАКЛАДУ ВИЩОЇ ОСВІТИ
Authors: Кабусь Наталя , Костіна Валентина
Published: December 2023

Виховна робота зі студентською молоддю набуває особливого значення
в умовах сучасного протистояння України російській військовій агресії,
бо дозволяє забезпечити впевненість у можливостях нашої держави зберегти
найцінніший скарб – генофонд нації та можливості її процвітання
у майбутньому. В умовах загрози свободи і незалежності, особливої важливості
збереження стійкості й сили духу для перемоги й подальшого сталого розвитку,
звернення до витоків мудрості українського народу, осмислення законів
і закономірностей прогресивного індивідуального і суспільного розвитку,
визначених видатними його світочами є, як ніколи, актуальним. До таких
неповторних постатей належить Г.С. Сковорода – найсамобутніший
український мислитель і просвітитель, шлях якого є взірцем для інших, творча
спадщина – золотим скарбом країни Автентичний спосіб його мислення
визначив орієнтири розвитку української нації, оскреслив «найважливіші риси
її ментальності – «трисонячну єдність», «сродну» працю, «філософію мудрого
серця» [5; 6]. Ми солідарні зі словами сучасного ученого Георгія Філіпчука,
академіка НАПН України, заступника голови Всеукраїнського товариства
«Просвіта», котрий відзначає, що які б нові пізнання не приходили в життя,
а давня мудрість завжди залишається непорушною [7, с. 1].
ІДЕЇ ГРИГОРІЯ СКОВОРОДИ І ЦІННОСТІ ОЛІМПІЗМУ: ПРИГАДУВАННЯ МАЙБУТНЬОГО
Authors: Вржеснєвський Іван , Вржеснєвська Ганна
Published: December 2023

Фізична досконалість і здоров’я є малодослідженою сторінкою
у творчості Григорія Сковороди. Але його ідеї, як буде показано нижче, мають
ефект пригадування майбутнього. Вони є співзвучними з комплексом етичних
настанов та досвідом піклування про себе, які утворюють систему цінностей
олімпізму. Останній можна розглядати як стратегію і водночас лабораторію
тілесного удосконалення людини засобами моралі та лабораторією самопізнання.
Сковорода, як відомо, вважав людське тіло «найдивовижнішою системою
всіх систем» [Сковорода 2005, т. 2: 338]. Ця система може адекватно
функціонувати лише у тому випадку, коли вона керується не споживацькими
інтересами, а вищими цінностями, розкриваючи потенціал тілесних
можливостей, окрилених духовно-душевною енергетикою. Своїм нащадкам
у вірші «Epigramma» Сковорода адресує такі рядки: «Назві коротко мужа
добре діло! – В умі май світло і здорове тіло» [Сковорода 2005, т. 1: 91].
Цей імператив є співзвучним новітнім тенденціям як в історії олімпійського
руху, так і в сучасній педагогіці.
PENGARUH KUALITAS PRODUK DAN HARGA TERHADAP KEPUTUSAN PEMBELIAN GITAR YAMAHA DI JAKARTA TIMUR
Authors: Nurul Setyawati  , Iwan Kurniawan Subagja
Published: December 2023

This research aims to test and determine the influence of product quality and price on purchasing decisions for Yamaha guitar products simultaneously and partially. The research was conducted on consumers who bought Yamaha products in East Jakarta. The sampling technique used purposive sampling and data analysis used multiple and simple linear regression analysis. The results of the research showed that product quality and price had a positive and significant effect both simultaneously and partially on purchasing decision.
PENGARUH RASIO UTANG TERHADAP EKUITAS DAN PENGEMBALIAN ASET TERHADAP HARGA SAHAM PERUSAHAAN SUB SEKTOR MAKANAN DAN MINUMAN YANG TERDAFTAR DI BURSA EFEK INDONESIA
Authors: Prayogi Malikul Akbar  , Diajeng Reztrianti
Published: December 2023

The purpose of this research is to find out the debt to equity ratio and return on asset simultaneously and partially affects the stock price of food and beverage sub sector companies listed on the Indonesian Stock Exchange This study used the purposive sampling. The results of this study is debt to equity ratio and return on assets simultaneously have a significant effect on stock prices in food and beverage sub-sector companies listed on the Indonesia Stock Exchange. Meanwhile, partially the debt to equity ratio has a significant negative effect on stock prices in food and beverage sub-sector companies listed on the Indonesia Stock Exchange and return on assets has a significant positive effect on stock prices in listed food and beverage sub-sector companies on the Indonesia Stock Exchange.
A prática docente na educação infantil: caminhos para a ecoformação e transdisciplinaridade
Authors: Saheb Daniele , Carvalho Mariana Da Rocha
Published: December 2023

O presente trabalho resultou de uma pesquisa de mestrado sobre a prática docente do professor de Educação Infantil, sob o viés da transdisciplinaridade e ecoformação. Partindo de um contexto pós- pandêmico, e da consequente falta de acesso a condições relevantes para o desenvolvimento integral, ressaltamos a importância das práticas da Educação Infantil como base da identidade planetária e individual, nesse sentido, indagou-se: como a prática docente pode contribuir para a ecoformação, com foco na transdisciplinaridade, na Educação Infantil? Para tanto, objetivou-se investigar as concepções dos professores da Educação Infantil, sobre transdisciplinaridade e ecoformação, buscando entender como a prática docente pode contribuir para a ecoformação, com foco na transdisciplinaridade, na Educação Infantil. A pesquisa de cunho qualitativo, inclui um panorama das investigações sobre o tema e a coleta de dados teve como participantes professores e coordenadoras de Educação Infantil de uma escola de Educação Básica, privada, localizada em Santa Felicidade, Curitiba-PR. O percurso metodológico escolhido amparou-se em Minayo (2014). As técnicas de coleta de dados utilizadas foram a entrevista semiestruturada, observação, questionário, e análise documental do Projeto Político Pedagógico. Os resultados apontaram que as concepções dos professores sobre complexidade e transdisciplinaridade consideram os sujeitos como multidimensionais, e que suas relações são fundamentais para sua constituição. Apesar destes termos não estarem presentes nos seus diálogos e nem no documento da instituição, foi possível perceber os seus princípios, estando também presentes na forma de pensar e agir dos professores. Palavras-chave: Educação Infantil. Prática Docente. Transdisciplinaridade. Ecoformação
A gestão escolar e aprendizagem discente sob o prisma da avaliação externa
Authors: Prudêncio Maíra Moreira , Vidal Eloisa Maia
Published: December 2023

O artigo realiza um mapeamento dos estudos que relacionam gestão escolar, avaliação externa e uso dos resultados. A metodologia utilizada foi a pesquisa qualitativa, com levantamento bibliográfico por meio do Estado da Questão, envolvendo pesquisa dos trabalhos acadêmicos – artigos e dissertações -, no Portal de Periódicos da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior e da Biblioteca Digital Brasileira de Teses e Dissertações (BDTD). Foram encontrados e analisados 24 trabalhos – 17 artigos e sete dissertações, cujos constatações permitiram a organização de quatro categorias:  nove trabalhos apresentam constatações em defesa do uso da avaliação externa como ferramenta para a gestão pedagógica e melhoria da aprendizagem discente; oito trabalhos apontam implicações das avaliações externas no cotidiano escolar, indicando aspectos que influenciam a gestão da escola e as práticas docentes, a partir da análise dos resultados; cinco trabalhos apontam efeitos danosos da avaliação externa no cotidiano escolar, destacando que sua adoção tem produzido efeitos que afetam a função social da escola, uma vez que esta passa a girar em tornos das avaliações, secundarizando outros aspectos do projeto político pedagógico; e dois trabalhos demonstram a necessidade de aperfeiçoamento das avaliações externas como ferramentas de informação para a gestão escolar, seja na forma como os resultados são apresentados, seja no que diz respeito à formação dos gestores e professores no uso das informações com finalidades pedagógicas. Os estudos ajudaram a compreender que o protagonismo das avaliações externas nas redes de ensino públicas tem aumentado e afetado gestores e professores, num processo de responsabilização distribuída.
Poesía, naturaleza y otredad animal: desafíos para nuevas pedagogías
Authors: Ruiz Javier Reyes , Rosales Elba Castro , Pereira Vilmar Alves
Published: December 2023

En el presente artículo se comparten hallazgos de una investigación interdisciplinaria bajo perspectivas críticas de la antropología, del arte, la teoría ambiental y la ecocrítica literaria, centrada en la pregunta ¿qué dice la poesía contemporánea sobre la naturaleza, en el contexto de una amplia crisis civilizatoria? El trabajo exploró el abordaje que poetas del occidente de México hacen sobre temas como la luz, el agua, los paisajes y los animales; sobre estos últimos gira el texto aquí presentado. Ello requirió un diseño hermenéutico dialógico, con registros etnográficos al poner en relación a poetas del occidente mexicano de los estados de Aguascalientes, Colima, Jalisco y Michoacán con educadores ambientales universitarios, además del análisis de casi 3.000 poemas contemporáneos de la zona citada. Se destacan resultados en los que se reconocen, tanto en la obra poética como en el diálogo con los autores, las posibilidades pedagógicas de poemas en los que los animales constituyen un núcleo temático. Entre los hallazgos sorprende, además, que los poemarios revisados abordan a la animalidad para celebrar la vida, elaborar reflexiones para conocer un lado distinto del vivir, y expresar el dolor por la devastación y el sufrimiento de seres vivos. Si bien en el presente texto se gira sobre el tema de los animales, estos están estrechamente entrelazados con otros elementos naturales presentes en la poesía, como la luz, el agua y los paisajes.
Histórias de vidas de dois sujeitos egressos da educação de jovens e adultos de uma favela carioca
Authors: Freitas Eduardo Silva de , Vermelho Sônia Cristina Soares Dias
Published: December 2023

A modalidade de Educação de Jovens e Adultos (EJA) é considerada como referência para o resgate de um tempo de estudo perdido, voltado àqueles que por algum motivo não tiveram acesso à escola. Também encontramos nas políticas públicas, referências de que a EJA pode atuar na emancipação dos indivíduos e, numa perspectiva pedagógica, de que pode contribuir para uma leitura de mundo mais crítica. Mas, que tipo de emancipação a EJA tem proporcionado aos seus estudantes? Tem contribuído para uma visão transformadora da realidade? Ou apenas vem atendendo aos princípios mercadológicos do modelo societário vigente? Para compreender esse contexto, realizamos pesquisa com dois indivíduos egressos da EJA, moradores de uma favela carioca. Ainda que nossos resultados não possam ser generalizados, contribuíram para entendermos que a passagem da classe trabalhadora por essa modalidade de ensino, dependendo da trajetória de vida e do contexto social em que se inserem, cumpre papel maior ou menor para inserção no mundo do trabalho. Esse acesso ao trabalho, leva ao entendimento de acesso a uma cidadania alicerçada no consumo de bens materiais e adaptação ao contexto socioeconômico vigente. Ainda que limitado o papel da EJA frente à perspectiva emancipatória, conforme defendem as teorias sociais críticas, do ponto de vista da condição do sujeito excluído socialmente, a EJA pode ser considerada como uma alternativa de ascensão social de cunho individual e material, e traz consequências profundas sobre a formação subjetiva.

Palavras-chave: Educação de Jovens e Adultos. Histórias de Vida. Emancipação Humana.
Prática interdisciplinar no ensino de Ciências Contábeis à luz da complexidade e da aprendizagem significativa
Authors: Barboza Fabiano De Almeida , Ohayon Pierre , Carvalho Marcia Da Silva
Published: December 2023

Este estudo tem como objetivo desenvolver uma contribuição teórica para o alcance da prática interdisciplinar no ensino contábil, com sustentações na Teoria da Complexidade e na Teoria da Aprendizagem Significativa. Por meio de um ensaio, essas teorias foram apresentadas e suas conexões com a interdisciplinaridade foram discutidas. Estudos anteriores reforçaram as ligações entre o raciocínio complexo, a interdisciplinaridade e a aprendizagem significativa. O raciocínio complexo pode proporcionar aos docentes e aos discentes uma visão integrada do curso de graduação em Ciências Contábeis, tornando-os conscientizados de que os conhecimentos abordados em uma disciplina podem se conectar a conhecimentos de disciplinas posteriores, estimulando a prática interdisciplinar. Professores e alunos desempenham papéis no atendimento dos pressupostos da aprendizagem significativa e se tais pressupostos forem atendidos entre disciplinas, e não apenas no âmbito de cada disciplina, ocorreria uma conexão da aprendizagem significativa com o raciocínio complexo, que juntos auxiliariam a operacionalização da prática interdisciplinar. Os entendimentos expostos neste estudo sugerem que a complexidade e a aprendizagem significativa podem dar sustentação teórica à prática interdisciplinar; estimular discentes a construírem conhecimentos integrados e a encontrarem soluções que não seriam possíveis em lentes disciplinares; conscientizar docentes sobre o significado de suas disciplinas para outras do curso e trazer ideias para praticar a interdisciplinaridade utilizando metodologias ativas. Este estudo contribui para a literatura do ensino superior visando o alcance da prática interdisciplinar, que para isso conta com a união do corpo docente e entre docentes e discentes para a concretização dessa prática.
IMPORTÂNCIA DOS PROGRAMAS DE RESIDÊNCIA PEDAGÓGICA E PIBID NA FORMAÇÃO DE PROFESSORES DE LICENCIATURA EM QUÍMICA
Authors: AGUSTINI DA SILVA TALISSON , CUSTODIO PEREIRA LEIVA
Published: December 2023

The training of chemistry teacher education plays a crucial role in the quality of science education. This summary addresses the importance of the Pedagogical Residency and the Institutional Program for Teaching Initiation Scholarships (PIBID) in the formation of these teachers, highlighting the benefits and impact of these initiatives. The research aims to analyze the relevance of Pedagogical Residency and PIBID programs in the education of chemistry teachers, with a focus on their pedagogical practice and student performance. The methodology employed consists of a comprehensive literature review, analyzing studies that explore theory-practice integration, practical experience in school environments, and the benefits of mentoring and support. The literature review provides insights into how these programs improve the quality of chemistry education and assist in the development of better-prepared and reflective teachers. The results emphasize the importance of Pedagogical Residency and PIBID programs in the education of chemistry teachers, highlighting the integration of theory and practice, pedagogical support, improvement in the quality of education, and continuous professional development. These initiatives benefit not only future teachers but also students in elementary schools.
Editorial
Authors: Martín María Pía , Monserrat María Alejandra
Published: December 2023

En 1993, hace treinta años, fue el puntapié inicial de un proyecto editorial, la revista Cuadernos del Ciesal, creada en el marco del Centro Interdisciplinario de Estudios Sociales Argentinos y Latinoamericanos -CIESAL- de la Facultad de Ciencia Política y Relaciones Internacionales de la Universidad Nacional de Rosario.

Su primer director y creador fue el historiador rosarino Ricardo Falcón quien retornó al país, desde su exilio europeo, en los primeros años de la vuelta a la democracia, insertándose en forma inmediata al quehacer universitario. Se involucró ante todo en la renovación académica y en la formación de jóvenes graduados para impulsar nuevos estudios e investigaciones, especialmente en el campo de la historia social, motivo por el cual convocó a diversos investigadores e investigadoras de la UNR a ser parte de un proyecto académico que tenía por objeto de estudio la cuestión social y la cuestión obrera en la Argentina de los siglos XIX y XX.

Un primer paso fue la creación del ya mencionado CIESAL. Este centro fue y es el lugar de reunión de investigadores provenientes de distintas áreas de las ciencias sociales, en el que conviven equipos que trabajan problemáticas diversas tanto en perspectiva de la Historia, como abordadas desde otras disciplinas como la Ciencia Política, la Sociología, la Antropología, la Arquitectura y el Urbanismo, la Economía.
Catalyzing Equitable Access to Building Construction Through Advancements in Global Building Machine Technology
Authors:   Marywood University, ANDRZEJEWSKI ELIZABETH , SHAFFER MARCUS ,   Pennsylvania State University, OBONYO ESTHER ,   Pennsylvania State University
Published: December 2023

Globally we are experiencing an unprecedented housing crisis. On December 26th 2019 as the United Nations called for the “Implementation of the Right to Adequate Housing”, they attribute our growing global housing crisis to unequal access to adequate housing caused, for the first time, by socio- economic inequality rather than access to building materials. As the wealthy buy and sell housing as a commodity, they increase their financial gains while driving the poor deeper into poverty. Among those driven deeper into poverty are more than 1 billion people living in informal settlements and more than 1.8 billion people lacking adequate housing. While inequity currently contributes heavily to our global housing crisis, we are experiencing a crisis of overlapping problems such as labor shortage, an ongoing pandemic, and worsening climate change.
The Theater of the People: A look into Queens Street Vending Culture
Authors:   The City College of New York, CRUZ PEDRO CRUZ
Published: December 2023

The Theater of the People project recognizes street vendors in Queens, Corona Plaza as merely the visible performance of a network of distributed and transient actors and social infrastructure. Simultaneously, an actual theater sits between a public plaza and a public park, offering a potential political, economic and social connection between the two public arenas. What can a building built for performance teach us when it becomes a scaffold for an entirely different play? How might we imagine a Theater for the People? Within the practice of everyday life, street vendors produce an inherently social space that’s embodied, processual, rhetorical, and political. What happens when a theater, a space of leisure that gives pleasure from the art of fiction, becomes the backdrop for the script of the street vendor? What would a space for the state- less look like? What role would the politics of aesthetics have in such a place? By portraying these relations and connections of everyday life interactions within public spaces, we can think of ways to invent new, inclusive futures.
Community Health Design: A Collaborative Framework for Improving Public Health Outcomes
Authors:   University of Kansas, KLEINMANN MATTHEW
Published: December 2023

The COVID-19 global pandemic has brought to light how public health outcomes are partially determined by governance and access to resources. In historically redlined communities, however, the availability and quality of neighborhood parks and grocery stores has been eroded by generations of disinvestment, leaving residents isolated as they work to build a healthier community. This paper shares the experiences of two community-led initiatives in Wyandotte County, Kansas, that have used community health design in collaborative settings to promote tangible improvements to green spaces and food systems during the pandemic.Both community health design case studies give context for how designers can reframe their methods of participation and collaboration and put them in service to community members who are closest to the issues being designed for. Building upon historical methods of participatory design, socially conscious designers can adopt principles of community engagement from public health practitioners and apply innovative research methods throughout the design process. The theories, processes, and outcomes of community health design illustrate a framework of participatory decision- making where designers can find common ground with the communities they serve.Though the pandemic did not introduce these conditions – park and food apartheids are symptomatic of a multi-generational epidemic of racism – this moment has highlighted the need for new ways of collaboration to address environ- mental health disparities. A framework of community health design is possible through the translation of community voices into a shared vision, designing governance structures to build community power, and turning design tools over to communities to define and achieve their desired publichealth outcomes.