bluuebunny/crossref_metadata_2025 huggingface dataset:
ПРОБЛЕМИ ТА ПЕРСПЕКТИВИ ДЕРЖАВНОЇ ІНСПЕКЦІЇ З ПИТАНЬ ІНТЕЛЕКТУАЛЬНОЇ ВЛАСНОСТІ: ІНСТИТУЦІЙНО-ПРАВОВІ АСПЕКТИ
Authors: Кірін Р. , Дорошенко О. , Дорожко Г. , Хоменко В.
Published: June 2022

Вступ. Інститут інспекторів з питань інтелектуальної власності (ІР) було створено відповідно до Указу Президента України в 2001 році. Він є важливими механізмом контролю держави за забезпеченням дотримання ІР-прав суб’єктів господарювання.Проблематика. Основними проблемами, пов’язаними із формуванням цього інституту, є: неврегульованість правового статусу інституту державних ІР-інспекторів і ІР-інспекції як інституції національної IP-системи; протиріччястатусу внутрішніх структурних підрозділів Мінекономіки та його IP-департаменту; необхідність визначення основних сфер вдосконалення інституційно-правового забезпечення контрольно-наглядової IP-діяльності.Мета. Дослідження інституційно-правових аспектів сучасних проблем та стратегічних перспектив державної інспекції з питань інтелектуальної власності.Матеріали й методи. Використано загальнонаукові та спеціально юридичні методи дослідження правових явищ такатегорій. Дослідження джерел IP-права, а також законодавства про контрольно-наглядову діяльність та про державну службу проведено з використанням методу системного аналізу та формально юридичного методу.Результати. Проведено аналіз нормативно-правової бази, що забезпечує регулювання контрольно-наглядових відносин в IP-сфері. Виявлено проблемні питання у правосуб’єктності державних IP-інспекторів.Висновки. Запропоновано шляхи вдосконалення інституційно-правового забезпечення контрольно-наглядовоїдіяльності в IP-сфері: розгляд питання не про інститут державних IP-інспекторів, а про державну IP-інспекцію як інституцію національної IP-системи; передавання контрольно-наглядових IP-повноважень та штату IP-інспекторів Держпродспоживслужбі; врегулювання питання про контрольно-наглядову IP-діяльність Мінекономіки і про державних IP-інспекторів; визначено основні сфери вдосконалення інституційно-правового забезпечення контрольнонаглядової IP-діяльності.
Du combat pour la « juste foi » au péché politique
Authors: Păun Radu G. , Biliarsky Ivan
Published: June 2022

As a manifesto of triumph over iconoclasm (843), the Synodikon of Orthodoxy provides a valuable insight into the study of the Orthodox doctrine through the centuries. The present work considers the Synodikon as a living text and as an object and a field of memory contests, invested in equal measure by the ecclesiastical authority and the monarchical power. The first part questions the relationship between various textual traditions and between text and ritual, the stakes of the liturgical commemoration, as well as the ways in which “right fait” and “sin” are periodically recast and employed as political arguments within the Neo-Hellenic, South Slavic and Muscovite cultures. The second part of the book retraces the history of the only known Romanian version of the Synodikon (Triôdion, Buzău, 1700) and analyses the political factors that shaped the liturgical apparatus in Romanian language. Introduced into the cult to support the anti-Catholic and anti-Calvinist policy promoted by the Wallachian prince Constantine Brâncoveanu (1688-1714) and by Patriarch Dosithéos II of Jerusalem (1669-1707), the Synodikon came out of use when the secular power could no longer support the ecclesiastical authorities’ initiatives. Although its memory lives on, the text never regained its place in the liturgy. The volume also includes critical editions of the Romanian texts of the Synodikon of Orthodoxy and of the Canon composed by the Ecumenical Patriarch Methodius I, a prosopographic dictionary, and the reproduction of the Slavic prototype of the Romanian Synodikon (Triôdion, Lviv, 1664).
Ordoliberalism Revisited
Authors: Remington Thomas F.
Published: June 2022

The recent publication of Kenneth Dyson’s book Conservative Liberalism, Liberalism, Ordo-Liberalism, and the State offers an occasion to reconsider the body of ideas known as ordoliberalism. The books reviewed here represent much of the most recent scholarship in English on the subject. In this essay, I undertake two tasks: first, to clarify what the term properly refers to and in particular how it is related to “neoliberalism,” and, second, to consider its influence on postwar German policies and institutions. I argue that much of the recent discussion of ordoliberalism and neoliberalism overlooks important differences between early ordoliberal thinking and the ideas associated with neoliberalism. Over time, as neoliberalism evolved and particularly as it became an ideological justification for policies and institutions justifying the accumulation of concentrated market power, these differences have become wider even as they have been obscured by misreadings of ordoliberalism. A better understanding of ordoliberalism can also provide insights relevant to the contemporary debates about the crisis of liberal democracy and capitalism. Is it in fact a “third way” for ordering an economy, an alternative to neoliberalism and socialism?
Assessment of Balance and Fatigue In COVID-19 Patients Admitted to a Tertiary Care Center: A Retrospective Analysis
Authors:   P.T. School and Centre, Seth G.S.M.C and KEM Hospital, Mumbai, Maharashtra, India., Deviprasad Lakshmiprabha , Hajare Bhagyashree ,   P.T. School and Centre, Seth G.S.M.C and KEM Hospital, Mumbai, Maharashtra, India., Rathod Krishna Sukhadev ,   P.T. School and Centre, Seth G.S.M.C and KEM Hospital, Mumbai, Maharashtra, India., Bhanushali Ankita ,   P.T. School and Centre, Seth G.S.M.C and KEM Hospital, Mumbai, Maharashtra, India., Mundhe Ashwini ,   P.T. School and Centre, Seth G.S.M.C and KEM Hospital, Mumbai, Maharashtra, India., Chury Shreya ,   P.T. School and Centre, Seth G.S.M.C and KEM Hospital, Mumbai, Maharashtra, India., Parikh Rutu ,   P.T. School and Centre, Seth G.S.M.C and KEM Hospital, Mumbai, Maharashtra, India., Iyer Saraswati ,   P.T. School and Centre, Seth G.S.M.C and KEM Hospital, Mumbai, Maharashtra, India.
Published: June 2022

Background: COVID-19 predominantly affects the respiratory system; however, evidence indicates a multisystem disease, with some patients presenting with neuromuscular and psychological sequelae. Impaired balance, and fatigue are frequently found in the patients with respiratory illness and is associated with functional impairments in daily life. Objectives: A Retrospective analysis of balance and fatigue in COVID-19 disease and identifying any influence of comorbidities on balance and fatigue with different disease severities will help us understand and widen the scope of physiotherapy interventions during COVID-19 and Post-COVID-19 rehabilitation Procedure: The Medical and Physiotherapy records of 67 patients, in the age group of 18 – 75 Years, admitted in a Tertiary care hospital with COVID-19 were considered from the period of September 2020 to March 2021. Data consisting of sex, severity of COVID-19, Oxygen status, comorbidities, SLS time for Static balance, FRT distance for dynamic balance and NRS score for fatigue, were considered for analysis while those on HFNC or Ventilator, unconscious patients or with altered sensorium, or musculoskeletal and neurological conditions were excluded. Results: FRT distance, SLS time and NRS scores were significantly reduced in those who were on oxygen supplementation as compared to those not on oxygen supplementation. There was a moderate negative correlation between age and FRT, SLS values of those who were on oxygen supplementation but not in those without oxygen supplementation. There was no significant difference in FRT, SLS & NRS values with or without comorbidities. Conclusion: Balance performances were significantly reduced and fatigue significantly increased in COVID-19 patients who were on supplemental oxygen. Age is also an important factor influencing balance in them. Comorbidities did not have any effect on balance and fatigue in different disease severities. Assessment of static balance, dynamic balance and fatigue should be considered as an important part of Physiotherapy routine assessments in patients with COVID-19. KEY WORDS: Static balance, Dynamic balance, Fatigue.
Prediction of the Type of Kinetic Curve
in the Process of Drying Potato Pulp
Authors: Pakhomov A. N. , Gatapova N. Ts. , Pakhomova Yu. V.
Published: June 2022

The application of the method for predicting the type of kinetic curves for drying dispersed products is shown, using the example of various methods
for drying potato pulp. A description is given of experimental setups that implement convective, conductive, and infrared drying. Thermograms and drying curves obtained under various modes are presented. The results of forecasting the kinetics of drying potato pulp for soft and hard drying modes are presented. Provisions of the developed forecasting method can be extended to a wider class of products, including colloidal systems, by refining the values of the limiting factors.
Conductive Organic Silicon Materials and Coatings Containing
Multilayer Carbon Nanotubes
Authors: Stolyarov R. A. , Memetova A. E. , Yagubov V. S. , Tkachev A. G. , Memetov N. R.
Published: June 2022

In this work, electrically conductive elastomers were obtained
by modifying the organosilicon compound with carbon nanotubes (CNT) “Taunit”
and “Taunit-M”. It was found that the use of CNTs with different structures had
a different effect on the electrical conductivity of nanomodified composites.
The maximum electrical conductivity of 6.94 × 10–9 S/cm of nanomodified composites was achieved at 30 wt. % content of CNT “Taunit”. In the case of using CNT “Taunit-M”, the maximum value of electrical conductivity of 3.06 × 10–2 S/cm was observed for
the nanomodified composite containing 6 wt.%. Preliminary drying and mechanical activation of CNTs led to an increase in electrical conductivity by one order
of magnitude as a whole.
Increasing the Efficiency of the Light-Absorbing Coating
of Solar Collectors
Authors: Bahaa E. , Tugolukov E. N.
Published: June 2022

A method for intensifying light absorption by the coating material of solar collectors based on the use of carbon nanotubes is considered. The increase in the optical absorption coefficient of the coating material was 11.7 %, the thermal conductivity of the coating material - 24.9 %, the ratio of the optical absorption coefficient to the thermal radiation coefficient (α/ε) - 9.2 %. The value of the mass concentration of carbon nanotubes in the coating layer, at which the stated results are achieved, has been established.
Lightweight Scheme for Smart Home Environments using Offloading Technique
Authors: A. Al-daraiseh Ahmad , Chowdhury Rasel , Ould-Slimane Hakima , Talhi Chamseddine , Bany Taha Mohammad
Published: June 2022

Internet of Things (IoT) as an emerging technology has been transforming the different aspects of our world from simple preprogrammed coffee machine to smart farming. Due to the human nature to simplify and ease of living, human are becoming dependent on these automated IoT devices and smart environments like smart phones, wearable devices, smart home and etc. In order to provide better QoS, these devices needs to work together and share data among them, also to the service providers and the cloud. Since these devices are resource constrained, IoT technology heavily depends on the cloud for processing, analytics and storage. But these data coming from the devices contains lot of personal identity information (PII). Almost all the time, the users of these devices are unaware of these information that is being transmitted or they do not possess the control over the data that they are being sent to the service provider, as well as to the cloud. Even the cloud services and service providers are secured but they are always curious. There are lot of security measures implemented for end to end communication but IoT lacks the mechanism for securing the data that the devices are generating along with access control. In this article we are proposing an approach for the security, privacy and access control of user data using Attribute Based Encryption (ABE) in smart home as the case study.
For the Publication of the First Issue of the Journal “China: Society and Culture”
Authors: Maslov Alexey
Published: June 2022

It is sometimes difficult to navigate in the flow of a huge number of international scientific publications about China and a growing number of journals. But it so happened that in Russia in recent years there have been no specialized scientific journals specifically on China, although Chinese studies are certainly actively covered in comprehensive journals on Oriental studies, history and philology, and international relations. And popular magazines and articles, even written by quite professional authors, can not replace the strictly scientific study of China.
Periodization of the Northern Song Emperor Huizong’s Reign (1100–1126)
Authors: Kozhukhov A lexander Yu.
Published: June 2022

This article is devoted to the reign of the de facto last Emperor of the Northern Song, Huizong. In particular, it deals with the question of how the periodization of the reign, based on mottos that were declared during the reign of the Emperor coincides with the theoretical periodization, based on the model of political struggle, as well as the question of whether the mottos of the reign can be considered as political institutions that include an official announcement of a change of political course. The dynamics of internal political processes, based on the analysis of the corresponding chapters of the historical chronicle of Song Shi, is demonstrated. As a result of the research, some discrepancies were revealed between the periodization based on the dynamics of internal political processes and the periodization using mottos, in particular, there were more mottos than the stages outlined during the research 6 and 5, respectively, a brief description of each stage is given.
Adaptation of the Quest Scale questionnaire to study the connection between the religiosity of women and their behavior during pregnancy
Authors: Maryanyan Anait Y. , Kuzmin Mikhail Y.
Published: June 2022

INTRODUCTION: This article presents the results of the adaptation of the Quest Scale questionnaire to study the religiosity in a Russian population, including women at different stages of pregnancy. The authors suggest that the study of religiosity as a personal quest is applicable when studying the religiosity of modern women. In addition, this study aimed to adapt the Quest Scale questionnaire to study the religiosity of women.
AIM: To adapt the Quest Scale questionnaire to investigate the religiosity of women.
MATERIAL AND METHODS: The questionnaire was adapted for 530 people (50, pilot sample; 162, a group of subjects of different genders and ages; 318, a group of women at different stages of pregnancy; M=32.8 years; SD, 8.27 years) of different levels of education and ethnic and religious affiliation. Consistency, reproducibility, and validity were determined using the Cronbach consistency coefficient , ICC coefficient, and factor analysis, respectively. In addition, Pearson correlation coefficient r was calculated on the basis of the index of basic spiritual experiences, which is a scale of religious orientation (G. Allport, D. Ross) to determine the structure of individual religiosity (Yu.V. Shcherbatykh). Calculations were performed in IBM SPSS 23.0 program.
RESULTS: During adaptation, the questionnaire with a high level of scale consistency was obtained: for the first scale willingness to solve existential problems without reducing their complexity =0.85; for the second scale positive perception of religious doubts =0.78; for the third scale openness to change =0.76. In addition, the level of scale consistency is higher in pregnant women, and lower in subjects of different genders and ages. A sufficient level of stability was recorded during repeated reproduction (ICC0.83 for the first scale, ICC0.75 for the second scale, and ICC0.85 for the third scale, p=0.0001). The factor structure of the questionnaire is also described. External validity was established during the discussion of the relationship between the scales of the Quest Scale questionnaire and the methods adapted for the Russian population.
CONCLUSIONS. The adapted Quest Scale questionnaire is suitable for studying the peculiarities of religiosity in the Russian population, primarily for women at different stages of pregnancy.
Comparative analysis of the treatment results of patients with breast cancer using various ­reconstruction methods
Authors: Kaganov Oleg I. , Orlov Nikita A. , Tkachev Maksim V.
Published: June 2022

Background. Breast cancer in many cases becomes the main cause of deterioration in the quality of life of patients due to the presence of severe postoperative asymmetry.Аim. To compare immediate and long-term results, quality of life indicators and cost-effectiveness in the treatment of patients diagnosed with breast cancer using an endoprosthesis and lipofilling reconstruction.
Material and methods. A prospective study of the treatment results of 72 patients diagnosed with breast cancer was carried out. Patients in the control group (n=40) underwent subcutaneous mastectomy with endoprosthesis plastics. Patients of the main group (n=32) underwent subcutaneous mastectomy with primary reconstruction by lipofilling. The calculation of indicators characterizing the efficiency of the use of hospital beds of a medical institution was carried out, the number of cases and days of temporary disability was calculated, an analysis of economic costs was made based on the tariff for a completed case of treatment of the disease. All statistical analyzes were performed using the Statistica 10.0 software. The study established a significance test of p 0.05.
Results. In the compared groups, the immediate results of surgical treatment did not differ statistically significantly (p=0.973), while the quality of life in patients after subcutaneous mastectomy with plastic lipofilling was significantly higher on the social functioning scale (0.004) than after reconstruction with the use of an endoprosthesis. When using the method of reconstruction with the use of lipofilling, it was possible to statistically significantly reduce the length of stay of patients in the hospital.
Conclusion. The use of lipofilling as a new method of reconstruction in patients diagnosed with breast cancer allows maintaining significantly high quality of life indicators on the scale of social functioning in comparison with the group of patients who underwent reconstruction with an endoprosthesis, and also makes it possible to significantly reduce the economic costs of treating patients.
Microstructural features of the thyroid gland in far eastern region goiter endemic zone inhabitants
Authors: Ageenko Kirill I.
Published: June 2022

Background. At present, the use of informative integration criteria for assessing the ecological well-being of the populations health is relevant. Monitoring of the morphofunctional parameters of the thyroid gland and its functional indices in inhabitants of different regions makes it possible to control the degree of tension of adaptive reserves in response to environmental influences.
Aim. Establishment of the features of the morphofunctional status of the thyroid parenchyma in inhabitants of the territory endemic for goiter in the Far East region.
Material and methods. 168 sectional thyroid glands without morphological signs of tissue pathology were used. Approaches were applied taking into account the age periodization of a person, depending on the mass of the gland and colloid-epithelial relations of the thyroid tissue (I epithelial, II epithelial, colloid types of glands). The qualitative and quantitative characteristics of thyroid gland macro- and microanatomy were studied.
Results. Based on cluster analysis, three morphological groups (types) of thyroid glands were identified: colloidal (61.9%), I epithelial (33.3%), II epithelial (4.7%). In the discriminant analysis, structural components that determine the assignment of the gland to a specific type (hormonal colloid and interfollicular epithelium) were established. In normal-weight glands, variants of the histostructure of colloidal and epithelial type I were equally found. For hypertrophied glands, the morphology of the colloidal type was characteristic (86.67%), the I epithelial type was slightly expressed (13.33%) and the II epithelial type was practically not found. It is determined that in the age aspect the colloidal type is the leading one.
Conclusion. Two factors morphological stability and functional activity, have been established, which can be considered as informative markers of compensatory-adaptive reactions and the level of activity of the thyroid tissue of far eastern region goiter endemic zone inhabitants.
Comparison of the diagnostic capabilities of fecal and serum markers in determining the severity of an ulcerative colitis attack
Authors: Bolotova Elena V. , Yumukyan Knara A. , Dudnikova Anna V.
Published: June 2022

Background. The clinical manifestations of ulcerative colitis are heterogeneous and may change over time. The main problem at present is the search for non-invasive diagnostic markers to assess the activity and severity of an attack in patients with ulcerative colitis.
Aim. Comparative evaluation of the diagnostic significance of serum and fecal biomarkers depending on the severity of an attack of ulcerative colitis.
Material and methods. 178 patients with ulcerative colitis were divided into 4 groups depending on the presence and severity of the attack, the control group included 40 patients with irritable bowel syndrome. The cytokine profile (interleukins-1, -2, -4, -6, -10, -17, tumor necrosis factor ) and the concentration of fecal markers (lactoferrin, calprotectin, neopterin) were determined, the clinical activity index (CAI) and scores according to Mayo scale were assessed. Dispersion, correlation and ROC analysis were used. The indicators are presented as M (SD) for parametric distribution and as Me (2575) for non-parametric distribution. Differences were considered statistically significant at p 0.05.
Results. Patients with ulcerative colitis showed a statistically significant correlation of Mayo scores with the CAI index (r=0.815, p=0.001), interleukin-6 (r=0.598, p=0.001), interleukin-17 (r=0.587, p=0.005 ), tumor necrosis factor (r=0.701, p=0.001), fecal calprotectin (r=0.881, p=0.001), lactoferrin (r=0.799, p=0.001), neopterin (r=0.791, p=0.001). Statistically significant correlations between CAI and interleukin-6 (r=0.525, p=0.001), interleukin-17 (r=0.587, p=0.005), tumor necrosis factor (r=0.624, p=0.001), fecal calprotectin (r=0.831, p=0.001), lactoferrin (r=0.672, p=0.005), neopterin (r=0.765, p=0.002) were found. Cut-off points for serum markers in predicting endoscopically active disease were as follows: interleukin-6 9.6 pg/ml, interleukin-17 6.6 pg/ml, tumor necrosis factor 7.6 pg/ml; cut-off points for fecal markers: calprotectin, 78.6 g/g; lactoferrin 765 g/g; neopterin 79.5 g/g.
Conclusion. A higher diagnostic significance of the use of fecal biomarkers compared to serum biomarkers, as well as the advantages of fecal calprotectin in terms of sensitivity and specificity among all the indicators we studied were revealed.
Early diagnostics and screening for ovarian cancer
Authors: Savinova Aigul R. , Gataullin Ilgiz G.
Published: June 2022

Ovarian cancer is the sixth most common cancer in women. The overall 5-year survival rate for ovarian cancer is approximately 40% due to the fact that most cases are diagnosed at late stages. Detection of ovarian cancer at the earliest possible stages is a public health priority. The article provides a review of existing scientific data regarding the early detection and screening of ovarian cancer, based on an analysis of publications in international electronic databases. Screening strategies are most effective for detecting diseases in their early stages, but at the moment there is no standard instrumental method that could be recommended as a screening examination for detecting ovarian cancer at an early stage. In this regard, most researchers have switched to the field of biomarkers and their combinations. Currently, more than 200 tumor markers, which are produced with varying intensity in ovarian cancer, have been proposed, but only two of them, CA-125 and HE4, have been tested in clinical experience. The article highlights the role of new tumor markers, multimarker panels, longitudinal algorithms in the early diagnosis of ovarian cancer. Most of the studies on the early diagnosis of ovarian cancer is aimed at searching for new biomarkers or developing multimodal algorithms that include both tumor markers, free deoxyribonucleic acid, and ultrasound of the pelvic organs. However, there are still no convincing data on mortality reduction based on randomized controlled trials, which stops doctors from including one or another strategy for the early diagnosis of ovarian cancer in national protocols and/or recommendations as a screening examination.
Oxaloacetate: signaling molecule, molecular mechanisms of interaction, prospects for clinical application
Authors: Kolotyeva Nataliya A. , Gilmiyarova Frida N. , Gusyakova Oksana A. , Sharafutdinova Irina A.
Published: June 2022

Small molecules make up a majority of cellular molecules, their intracellular concentrations vary over a wide range, and they are involved in a multifarious molecular transformations. However, there is not enough information about how small molecules regulate protein functions through intermolecular binding, which creates an urgent need for fundamental research and the study of the metabolites role. Our attention was focused on small molecules located at the intersection point of metabolic pathways of proteins, fats, carbohydrates, the structural and functional potential of which provides numerous biomolecular processes. The intermediates availability can regulate energy and intermediate metabolism, cellular redox potential, and production of adenosine triphosphate, determining the direction of metabolism that is priority for the cell at this point in time. Of particular interest in the study of metabolite-protein interactions are those studies that can reveal new enzyme-substrate relationships and cases of metabolite-induced remodeling of protein complexes. The review is devoted to the study of the role of the small molecule oxaloacetate and malate, as well as malate dehydrogenase involved in their transformations, the activity of which can be used as a diagnostic marker in oncological and neurodegenerative diseases. Oxaloacetate has protective and promitochondrial effects, it serves as a neuroprotector, prevents inflammation and neurodegeneration. The penetration of oxaloacetate through the blood-brain barrier into the central nervous system was established, which became a prerequisite for conducting preclinical trials of drugs containing it in models of Alzheimer's disease and ischemic stroke.
Experience in using a minimally invasive method for removing salivary gland duct calculus under sonography control
Authors: Ivanov Oleg A. , Sharafislamov Iskander F. , Voronina Elina  M. , Ksembaev Said S. , Khamzin Ildar I.
Published: June 2022

Background. Removal of calculi in salivary stone disease is one of the urgent problems of maxillofacial surgery and surgical dentistry due to the complexity of the manipulation, the trauma of the technique and the frequent development of complications.
Aim. Improvement of the treatment results of patients with salivary stone disease by using our developed method of minimally invasive removal of calculi located in any part of the excretory duct of the submandibular and/or parotid salivary glands, under constant ultrasound visualization of the intervention.
Material and methods. The study included patients diagnosed with salivary stone disease (10 people: 9 male and 1 female aged 1850 years, mean age 44.21.25 years). The methodology was as follows. An ultrasonic sensor was brought in from the side of the skin, and the location of the calculus in the gland duct was determined. Next, a needle with a diameter of 0.3 cm with a mandrin was inserted percutaneously through a puncture into the duct of the salivary gland to the distal surface of the calculus, and it was advanced with the help of a needle as far as possible towards the mouth of the excretory duct. Then the needle was removed, leaving a mandrel in the duct, with which the calculus was fixed in a new position. After bougienage of the excretory duct, Dormias basket was introduced into it, and the calculus was captured and removed. The manipulations were performed under constant ultrasound imaging.
Results. The use of the technique developed by us for minimally invasive removal of a calculus with a diameter of up to 5 mm, located in any part of the excretory duct of the submandibular and/or parotid salivary glands, under constant ultrasound visualization of the intervention course, made it possible to achieve a positive result in all 10 patients included in clinical observations.
Conclusion. The minimally invasive technique for removing calculi from the excretory ducts of the salivary glands under constant ultrasound imaging developed by us makes it possible to facilitate manipulation, its visibility and accuracy, as well as atraumaticity and prevention of complications.
The acute necrotizing periorbital fasciitis. Clinical case
Authors: Haritonova Natalia N. , Gorbachev Dmitriy S. , Safonov Maksim S. , Kolbin Aleksey A. , Kulikov Alexey N. , Kolke Alena A. , Batyrshin Ildar M. , Zinoviev Evgeny  V.
Published: June 2022

BACKGROUND: A rare severe, characterized by high mortality in some localizations (up to 70%) necrotizing periorbital fasciitis has not been described previously in the national literature.
AIM: to show a multidisciplinary approach to the treatment and rehabilitation of patients with periorbital necrotizing fasciitis on the example of the clinical case.
CLINICAL CASE: Patient with the acute necrotizing fasciitis of both eyelids, with the dissemination to the superficial face and neck fascies, the sepsis development is given. Monitoring of vital functions, homeostasis indicators, repeated inoculations, computed tomography, regular examination by an ophthalmologist included the control of visual functions, anterior and posterior segments, closure of the eye fissure. Conservative and surgical treatment applied by a multidisciplinary team is presented, which allowed to save the patients life, overpass the purulent-necrotic, and then the rough scar process and to achieve satisfactory anatomical and functional results.
CONCLUSION: Timely multidisciplinary treatment of periorbital necrotizing fasciitis is necessary for the life preservation, prevention of severe complications from the eye. With the threat of developing lagophthalmos, it is necessary to perform permanent blepharoraphy for 36 months after the first surgery and further surgical and pharmacological correction of scarring processes.
Cytomegalovirus uveitis in HIV-infected people: possible complications
Authors: Sizova Tatiana D. , Khokkanen Valentina M. , Zumbulidze Natalia G.
Published: June 2022

BACKGROUND: Cytomegalovirus uveitis is an AIDS-marker disease. If typical chorioretinal foci associated with cytomegalovirus viremia, inflammatory diseases of cytomegalovirus etiology of other organs are detected, etiotropic treatment and antiretroviral therapy are prescribed. Later on, the patient continues to be monitored by an ophthalmologist.
AIM: The aim is to identify the structure of complications, the frequency and the timing of their occurrence in cytomegalovirus uveitis in HIV-infected patients, the relationship with the treatment.
MATERIALS AND METHODS: The study was performed at the St. Petersburg Center for the Prevention and Control of AIDS and Infectious Diseases and the Department of Ophthalmology of the North-Western State Medical University named after I.I. Mechnikov. The study group consisted of 66 patients (97 eyes).
RESULTS: The development of complications of the disease was detected in 86.6% of patients. In patients, following complications were reported: retinal detachment, complicated cataract, partial optic nerve atrophy, cystoid macular edema, and secondary exotropia.
CONCLUSION: Cytomegalovirus uveitis in HIV-infected patients has a predominantly complicated course.
Mapping Motion Direction to Color in Ground-Motion Visualizations—A Tool with Potential Applications in Different Settings
Authors: Bezada Maximiliano J.
Published: June 2022

The increase in seismometer density on a continental scale since the start of the EarthScope project has enabled the community to produce visualizations of the propagating wavefield from local and teleseismic events. Previous work has shown that these animations generate much interest yet have limitations and can be confusing to novices. Here, we present a new type of visualization in which the color, position, and size of the symbols representing each seismometer are time dependent and determined by the instantaneous proportion of motion in the Z, R, and T components. This color-mapping scheme has the advantage of automatically producing different colors for different wave types and results in vibrant animations. The color mapping is based on transforming the value of the envelopes of the filtered velocity traces to red–green–blue values and subsequently boosting the color saturation in the hue–saturation–value color space. Animations in map view and along great-circle paths have been produced and used in a formal classroom setting and have also been shared with the broader public through social media channels. In both formal and informal settings, the animations have succeeded in garnering attention and stimulating discussion.
Método Para Simular Amostras Probabilísticas Com Imagens Em Planilha: Uma Aplicação Educacional Em Biologia
Authors: Frei Fernando , Santiago Glauber Lúcio Alves
Published: June 2022

ResumoO ensino de Estatística é parte integrante de currículos de diversas áreas do conhecimento no ensino superior. Especificamente, a Estatística Inferencial necessita de novas práticas pedagógicas para superar o pensamento determinístico apresentados por muitos estudantes de maneira a desenvolver uma transição para conceitos probabilísticos, a base da Inferência Estatística. Neste sentido, este artigo tem como objetivo apresentar um recurso didático para simular amostras, com imagens em planilha com o propósito de desenvolver conceitos estatísticos inferenciais associados à resolução de problemas práticos na área de Biologia. O desenho de pesquisa utilizado para o trabalho em foco foi quantitativo, exploratório e descritivo. Os resultados sobre a aprendizagem dos conceitos estatísticos inferências foram positivos. No que diz respeito a avaliação dos alunos, 77% consideram que a atividade apresenta interdisciplinaridade e dinamismo o que contribuiu para entender os conceitos do processo de estimativa por Intervalo de Confiança. As atividades com o uso da simulação com imagens em planilha mostraram que o procedimento adotado pode ser um aliado no ensino da inferência, e que a combinação da simulação e de atividades práticas envolvendo a simulação com imagens pode enriquecer a aprendizagem.
Palavras-chave: Educação Estatística. Intervalo de Confiança. Simulação com imagens.
AbstractThe teaching of statistics is an integral part of the curricula of several knowledge fields in higher education. Specifically, inferential statistics needs new pedagogical practices in order to overcome the deterministic thinking of a number of students and develop a transition to probabilistic concepts, the basis of statistical inference. Therefore, this article aims to present a didactic method to simulate samples through images in a spreadsheet with the objective of developing inferential statistics concepts associated with the solution of practical problems in Biology. The research design used in this work was qualitative, exploratory and descriptive. On average the results concerning the learning of inferential statistics were 70% positive. As regarding students evaluation, 77% consider that the activity is both interdisciplinary and dynamic, which contributes to the understanding of the concepts of the Confidence Interval estimation process. The activities using simulation through images in spreadsheets have shown that the procedure can be an ally in the teaching of inference and that the combination of simulation and practical activities can enrich the learning environment.
Keywords: Statistical Education. Confidence Interval. Simulation with Images.
Review of International Accounting Information Systems
Authors: Beke Jeno
Published: June 2022

This paper traces the benefits of international accounting information systems-their contribution to standardization and harmonization by purposing and tasking for business management. In this review, the goal is to describe and summarize how the accounting information system can help management decisions and influence the business environment on a global scale. The unified, standardized accounting information system will lead to new types of analysis and data, furthermore with the possible integration of new indicators from the business management practice of certain countries. The purpose of this study was the measure the differences between the national rules and the international methods by countries, then the value and analyze their effects on the business environments. The study showed that both business earnings and stock returns affect management turnover. Businesses with lower labor productivity compared to their industry peers have greater incentives to adopt an international accounting system. However, the results on turnover are sensitive to this change in variable specification. So the increase in the sensitivity of turnover to accounting performance postadoption is primarily driven by heightened turnover sensitivity to accounting losses. The empirical results could be the author’s suggestions for business management.

JEL Classification Code: M40, M41, M48
Cost Structure and Profit Stability: A Comparative Study between CMC- Kamal Textile Mills Ltd. and Square Textile Ltd.
Authors: Ahamed Md. Jafaur
Published: June 2022

The cost structure is an important concept to be aware of and to be understood by all the concerned persons in any manufacturing or service providing organization conducting any economic activity and with an aim to improve quality of service as well as increasing productivity and profitability. In this study, an attempt has been made to compare the cost structure and show the impact of cost structure on profit stability between CMC-Kamal textile mills ltd. and Square textile ltd. The study reveals that CMC-Kamal textile mills ltd. enjoys wider movement in net income as changes take place in sales, with greater profit in business good years and greater losses in business bad years. On the other hand, Square textile mills ltd. enjoys somewhat greater stability in net income i.e. Square textile ltd. is less vulnerable to downturns than CMC-Kamal textile mills ltd., but it will do so at the risk of losing substantial profits if sales trend upwards in the long run. Researchers also found, due to consisting of lower fixed cost, square textile ltd. has a lower break-even point and a higher margin of safety; therefore, it will reach the profit as quickly as CMC-Kamal textile mills ltd. in the periods of sharply declining sales. The study also highlights the problems regarding cost structure and suggests how to overcome these problems.

JEL Classification Code: D61, P52, L67, M49
Changing World Economic and Financial Scenario
Authors: Awan Abdul Ghafoor
Published: June 2022

The dawn of the 21st century has changed the scene of the world economy and shifted the center of economic growth from the Western hemisphere to the Asian Continent. The global financial crisis of 2008 and the European debt crisis of 2010 have exposed the inherent weakness of G-7 economies, which are facing the challenges of twin deficits, falling productivity, rising debts, and an aging population. In contrast, the emerging economies particularly, China, India, and Brazil, have shown robust economic growth from 2000 to 2010. The objective of this paper is to measure the changes taking place in the world economy from 2000 to 2010 and their impact on asset allocation, employment, poverty, and allocation of resources. For this purpose, the author has selected total of 14 countries as a sample and divided them into two groups: G-7 and E-7. The G-7group Includes the USA, Germany, France, UK, Italy, Japan, and Canada while E-7 contains China, India, Brazil, Russia, Indonesia, Turkey, and Pakistan.

The methodology used in the study is to compare different economic and financial indicators of these two groups of countries in order to obtain desired results. Mostly time series and cross-sectional secondary data, collected from the database of IMF, World Bank, US Federal reserves, relevant international research journals, and books, have been used. Different statistical techniques such as trend analysis and ratio analysis have been applied to measure the changes in selected variables. The results of the study are very encouraging. We found that increase in the national income of emerging economies has brought trickle-down effects and reduced poverty and inequality level in emerging economies. Only in China, about 400 million people have come out of the poverty trap due to rising employment opportunities. The share of E-7 economies in the world R & D has increased from14% in 2001 to 20.1% in 2007, while the share of G-7 economies has declined by 2.4% during the same period.

The study found the declining trend of productivity levels in G-7 countries vis-à-vis E-7 countries. The anti-migrants policy of G-7 countries is one of the contributing factors to the decline of productivity. This study endorses the views of Blanchard (1997), David Romer (2001), Yuan Langwiler (2004), David C. Colander (2004), Andrew Glyn(2006), and John Hawksworth (2007) who contended that the USA will no more be a world economic power and China will likely to overtake her as world economic leader by mid of 21st century.
Capital Structure Determinants: Evidence from Manufacturing and Services Sector Companies in Sri Lanka
Authors: Buvanendra S.
Published: June 2022

This paper develops a preliminary study to explore the determinants of capital structure of Sri Lankan listed manufacturing and services sector companies using firm-level panel data for the period of 2003 – 2007. Profitability, Tangibility, Size, and Growth rate were used as independent variables, while leverage ratios such as total debt ratio, long-term debt ratio, and short-term debt ratio were the dependent variables.OLS dummy regression model was used here. The results revealed that only the profitability variable was statistically significant with leverage ratios (with total debt ratio and short-term debt ratio) at manufacturing companies. Meanwhile, all the selected variables, except tangibility were significantly related to at least one of the leverage ratios in services companies. The results of this study validate the prediction of pecking order theory in the case of profitability variables in both manufacturing and services companies. Also growth variable of services companies again confirms the pecking order hypothesis. However size variable of services companies confirms to the prediction of trade-off and agency cost theory.
Does National Diversity Impact Conflict in Global Virtual Teams? The Role of Language Factors
Authors: Soares Ana Maria , Stephens Robert , Dong Longzhu
Published: June 2022

This study looks at the impact of national diversity on task and relationship conflict in the context of global virtual teams (GVTs). We investigate the interaction effects of both English skills and openness to linguistic diversity on these relationships. We administered a questionnaire to 283 GVTs working on a collaborative experiential learning project to develop an international business plan. Our results show that, for teams exhibiting high levels of openness to linguistic diversity and high levels of English skills, increased levels of national diversity on the team are associated with lower levels of task and relationship conflict. The relationship is reversed, however, in teams where openness to linguistic diversity and team English skills are low. These findings shed light on the relationship between national diversity and conflict by suggesting that both English skills and team attitudes toward language diversity are important in reducing conflict. Moreover, openness to linguistic diversity may be more important in reducing conflict than the level of team members’ language proficiency.
Systematic assessment of pathophysiological mechanisms and their interrelation in progression of Alzheimer’s disease
Authors: Mittal Sunita , Sharma Akriti Kapila , Mittal Gauri , Mahadule Ashwini , Pathania Monica
Published: June 2022

Alzheimer’s disease (AD) consists of 60-80% of all dementia cases, thus is recognized as the commonest form of dementia. The current challenge to clinicians and researchers in the field of AD is development of treatment plans that can target the progression of pathology at molecular level as well newer diagnostic techniques for early detection and prevention of AD. This could be achieved by enhancing our understanding of the underlying pathophysiology of AD. This is systematic and concise review of various pathophysiological mechanisms contributing to AD.

Legitimate indexing portals and search websites were used to carry out the literature search for this article. A combination of MeSH terms and Boolean operators were used. Obtained research articles were carefully assessed first by reading title and abstract and finally by reading the whole text. A set of inclusion and exclusion criteria were used to select the reference articles.

: In our literature search 75 articles were obtained from PubMed, Google scholar and Cochrane Library after removing duplicate records. These were screened using titles and abstract. 23 articles were excluded from the study as per the exclusion criteria. Full text of 52 articles were read. 7 articles were excluded, 45 were studied thoughrouly and 30 were referenced during the writing of this review.

Various risk factors – old age, diabetes, smoking, mutation etc contribute to Aβ plaque accumulation due to cleavage of APP protein by α and ϒ secretase. Aβ plaque further contributes to accumulation of neurofibrillary tangles, neuroinflammation and oxidative stress. This together with disturbance in Calcium homeostasis and excitotoxicity at glutamate receptors contribute to neurodegeneration and synaptic toxicity.