bluuebunny/crossref_metadata_2025 huggingface dataset:
A Case Study on the Benefits of Implementing an Introductory Short Course on Oil and Gas to High-School Students
Authors: Alyafei Nayef , Retnanto Albertus , Cieslinski G. Benjamin
Published: September 2022

This paper highlights the benefits of a five-day short course on the basics of petroleum engineering for high-school students. Moreover, the course aims to introduce the oil and gas sector to students and stimulate their interest in considering petroleum engineering as a major in their future studies. The five-day short course was designed for two contact hours per day (a total of ten hours). The format adopted was approximately one hour covering the technical content, followed by one hour of experimentations. The course was conducted virtually, where the instructor conducted all the experiments. The students were encouraged to participate and take notes to make the session more dynamic. This paper will discuss the exact content covered every day in both lectures and experiments for people to follow. The equipment used in all experiments was very simple and easily procured. Twenty of the student participants filled out a survey at the end of the program. The outcome highly indicates that the students demonstrated a good understanding of the oil and gas sector as well as the objectives of considering petroleum engineering as a major. This program attempts to build bridges between the STEM education pipeline and the new demand for talent in the oil and gas sector. The novelty of this work is the high impact we observed on students’ motivation and potential enrollment to study petroleum engineering. Overall, the program is short and offers simple yet engaging content. Any school can easily adapt this program, and in this paper, we provide detailed guidelines to do so.
Increase in the Oil Recovery Factor through the Injection of Nano-Chemicals Dispersed in Gas
Authors: Gallego Arias Jhon Fredy
Published: September 2022

Tight reservoirs have different challenges, among them, there are several related to the low permeability of the rock and diverse damage mechanisms. Conventional Chemical Injection in these types of reservoirs has some disadvantages such as shallow penetration and the use of high volumes of chemicals. Therefore, new technologies such as chemical dispersion on a gas flow have been developed to achieve deeper penetration of the chemicals and mitigate formation damage in gas- condensate tight reservoirs by mobilizing condensate banks. However, the inclusion of nanoparticles in the dispersed phase for EOR processes is a novelty. Since silica nanoparticles reduce interfacial tension and alter the wettability of the rock, the objective of this study is to evaluate the effect of adding silica nanoparticles (S1) dispersed in two treatments (A and B) at a dosage of (10-100 mg·L−1) on wettability, interfacial tension, emulsion stability, and rock treatment adsorption. To compare them with a silica-based nanofluid, treatment C was also evaluated. The dosage selection of silica nanoparticles was made through static tests such as interfacial tension, contact angle, and static formation of emulsions. The best nanofluid among the ones prepared from treatments A and B was evaluated in dynamic tests to be compared with treatment C through the capillary blockage, oil recovery, and oil recovery in the perdurability scenario tests. Treatments A and C experienced a great affinity for the rock in the adsorption isotherms, while treatment B had less affinity for the rock. The addition of nanoparticles (S1) to treatments A and B at a concentration of 50 and 10 mg·L−1 respectively, led to an interfacial tension reduction of 16% and 40%, each one; and a respective water contact angle reduction of 17% and 2%. Furthermore, the addition of nanoparticles S1 promoted less stable emulsions, which is favorable for these processes. Finally, 26% of the additional increase in oil recovery and a greater perdurability was obtained with treatment B + 10 ppm Nps S1 in core displacement tests.
Detection of Emerging Ibrutinib Resistance by Flow Cytometry in Patients with Chronic Lymphocytic Leukaemia
Authors: Takács Ferenc , Kotmayer Lili , Czeti Ágnes , Szalóki Gábor , László Tamás , Mikala Gábor , Márk Ágnes , Masszi András , Farkas Péter , Plander Márk , Weisinger Júlia , Demeter Judit , Fekete Sándor , Szerafin László , Deák Beáta Margit , Szaleczky Erika , Borbényi Zita , Sulák Adrienn , Barna Gábor
Published: September 2022

Background: Although ibrutinib is effective drug in the treatment of chronic lymphocytic leukaemia (CLL), during the treatment acquired resistance may occur, making its detection an important issue. We aimed to find phenotypic markers on CLL cells which expression may correlate with the appearance of ibrutinib resistance.
Methods: We examined 28 (treatment naïve, ibrutinib sensitive, clinically ibrutinib resistant) peripheral blood (PB) samples. The surface markers` expression (CD69, CD184, CD86, CD185, CD27) were assessed by flow cytometry. Furthermore, the BTKC481S resistance mutation was tested using digital droplet PCR. We also investigated the change of the phenotype of CLL cells during ibrutinib treatment in one patient with acquired ibrutinib resistance.
Results: The expression of CD27 (p=0.016), CD69 (p=0.015) and CD86 (p=0.015) was higher in the clinically resistant cohort than in the ibrutinib sensitive cohort. Besides, we found that high CD86 and CD27 expressions accompanied by BTKC481S mutation. Our prospective study showed that the increase of the expression of CD27, CD69, and CD86 was ahead of clinical resistance with three months.
Conclusion: Our study suggests that the flow cytometric measurements of certain markers may reveal and predict the development of ibrutinib resistance, and this method may in the future become a part of the follow-up on patients treated with ibrutinib.
Flood as a fine scale driver of both floristic and functional differentiation in a ripariansystem
Authors: Miranda¹ Kaline Fernandes , Coelho² Polyanne Aparecida , Araújo¹ Felipe Carvalho , Morelli² Mariana Caroline Moreira , Pereira¹ Diego Gualberto Sales , de Paula Gabriela Gabriela Gomes Pires , de Souza Cléber Rodrigo , Santos Rubens Manoel dos
Published: September 2022

Flood forests are vegetation subject to seasonal floods. Situated in flood plains, they are systems under continuous changes due to the pulses of flooding, following the watercourse. Although these are singular ecosystems, there are little publications that report the floristic structure in floodplains, especially in Southeastern Brazil. This study aimed to characterize the composition, structure and diversity of the arboreal community in a flooding gradient, comparing them with the non-flood adjacent formations, at the mouth of Paracatu River, a tributary of São Francisco River, Minas Gerais, Brazil. For the structural survey of the arboreal community, we used the plot method, installed on both sides of Paracatu River. The individuals were identified at the species level. We sampled 1,276 individuals belonging to 85 species and 32 families. The Shannon Index (H`) regarding to the total sampling was of 3.40 nat.ind, with Pielou evenness index (J`) of 0.76. In terms of species importance, the six most important species comprised 46% of the total index of importance value. By means of similarity analysis, it was possible to verify the grouping of species along the ecounits, demonstrating the substitution of species along habitats, resulted of the temporal difference of the flooding in the environments. In conclusion, the flooding regimes, frequency and intensity determine the ecology of the river plains.
X-photon laser direct write 3D nanolithography
Authors: Skliutas Edvinas , Samsonas Danielius , Čiburys Arūnas , Kontenis Lukas , Gailevicius Darius , Berzinš Jonas , Narbutis Donatas , Jukna Vytautas , Vengris Mikas , Juodkazis Saulius , Malinauskas Mangirdas
Published: September 2022

Polymerized voxels by focusing ultrashort pulses varying wavelength over three-octaves wide range for femtosecond laser direct write 3D nanoprinting are studied. A possibility to use any color of spectrum from 500-nm-to-1200-nm with a controlled pulse width of 100-fs reveals a delicate interplay of photo-physical mechanisms more than just two-photon absorption inducing localized photo-polymerization. None of the applied exposure conditions ensured significantly higher spatial definition than 200-nm in width using SZ2080TM photosensitized and pure materials, yet it allowed tuning the voxel aspect ratio and greatly influenced dynamic fabrication window determined by the resolution bridges method. An effective order of absorption, i.e., the n ef -photon process of absorption, and exposure per pulse (energy, fluence, intensity) was assessed for ultra-short pulses varying wavelengths as it has the paramount influence to the established multi-photon polymerization (MPP) process. Here an evolution of the polymerised volume via different energy delivery mechanisms: one-/two-/three-photon absorption, avalanche ionization, and thermal diffusion leading to controlled photo-polymerization are revealed. The results can be used to tailor polymerized volume for increasing the 3D nano-printing performance. A non-trivial energy deposition by X-photon absorption was observed with an onset of a strong lateral size increase at the higher pulse energy at longer wavelengths and can be understood as due to reaching epsilon-near-zero conditions. Findings are valuable for developing MPP technology to reduce the footprint size and increase its efficiency. Understanding mechanisms and appearance of λ -tunable commercial lasers are benefiting broad applications in advanced optical additive manufacturing areas of micro-optics, nano-photonic devices, meta-materials, and integrated-chips, and tissue engineering.
Investigation on the Damping of Riveted Short Cantilever Beams With Layers of Similar and Dissimilar Metallic Materials: Optimization of Parameters
Authors:   Siva Sankara Rao Yemineni1,   Prof. Mallikarjuna Rao Kutchibotla2,   Prof. V. V. Subba rao3
Published: September 2022

Investigating the damping behavior is essential for any dynamically vibrating structures to avoid resonance. For this, one of the ways is to make the vibrating metallic beams into layers throughout their thickness and rivet them. So far in the previous investigation, the layers considered are of the same materials for both the long and short beams. In this investigation, the layers considered are of both similar (mild steel-mild steel (MS + MS) and aluminum-aluminum (AL + AL)) and dissimilar metallic materials (mild steel-aluminum (MS + AL)) and are shorter in length. The Frequency response function (FRF), Euler-Bernoulli theory (EBT), and Timoshenko beam theory (TBT) were adopted to investigate the damping ratios and their order is found to be \(\varvec{\xi }\)FRF>\(\varvec{\xi }\)EBT>\(\varvec{\xi }\)TBT. A combination of mild steel-mild steel showed higher damping ratios when compared with the other two riveted materials combinations and the order for damping ratio is \(\varvec{\xi }\)MS−MS>\(\varvec{\xi }\)MS−AL>)\(\varvec{\xi }\)AL−AL. In addition, the parameters that affect the damping ratio of riveted short cantilever beams with mild steel-aluminum metallic materials combination were optimized by considering the full factorial design using response surface methodology (RSM), and corresponding plots were presented to observe the variation of the damping ratio. The minimum and maximum damping ratios were also obtained within the range of numerical values of the parameters considered in this study. At last, a quadratic regression equation was developed for cantilever beams with mild steel-aluminum (MS+AL) materials combination and was validated by experimental values that were not utilized in its development.
Comorbidities in patients with uterine adenosarcoma. A single-center case series of 12 patients
Authors: Du Hui , Jiang Jingjing , Wang Zhu , Peng Hongfa
Published: September 2022

Background: Uterine adenosarcoma is a rare low-grade tumor that commonly affects elderly women and is associated with a generally good, although sometimes poor, prognosis. This study investigates the effect of comorbidities in old patients with uterine adenosarcoma.
Methods: A review of patients who had been diagnosed with uterine adenosarcoma at our institution between 2010 and 2020 was conducted. All patients underwent a specialist pathological reviewand were re-staged according to the International Federation of Gynecology and Obstetrics 2009 criteria. Patient demographics, staging, histologic features, primary and adjuvant therapy, disease recurrence, and survival time were collected.
Results: Twelve patients with confirmed uterine adenosarcomas were identified. Their mean age at diagnosis was 58.3 years (range, 31–83 years). Eight patients had pre-existing chronic diseases at the time of diagnosis. All 12 patients underwent surgical therapy. Of these, 10 (83.3%) were stage I, 1 (8.3%) was stage II, and 1 (8.3%) was stage III. Postoperative adjuvant therapies included chemotherapy (n = 1), radiation (n = 1), or no further therapy (n = 10). The mean follow-up duration was 39.2 months (range, 7–104 months). The recurrence and mortality rates were 16.7% (2/12) and 41.7% (5/12), respectively. Five recurrence-free patients died of comorbidities. The mean postoperative survival of these 5 patients was 22.6 months. The remaining seven patients were free of recurrence at the time of this report.
Conclusions: Comorbidities with age is a significant factor leading to poor prognosis in uterine adenosarcomas. Greater attention should be paid to elderly patients with comorbidities. Targeted interventions, including multi-professional management, tailored assessment, and follow-up, may contribute to improved well-being.
Labile carbon inputs support the recovery of prokaryotic communities, but not fungal communities, from a simulated bovine urine event.
Authors: Dopheide Andrew , Davis Carina , Wakelin Steve A , Whitehead David , Grelet Gwen-Aëlle
Published: September 2022

Inputs of carbon to soil may be used to stimulate microbial growth and immobilize excess nitrogen from sources such as livestock urine. However, the growth responses of microbial taxa to carbon inputs under conditions of excess soil nitrogen remain poorly understood. Using DNA metabarcoding and a field-based soil lysimeter experiment, we characterised the temporal responses (up to 112 days) of bacterial and fungal communities to a simulated bovine urine event plus inputs of labile carbon (sucrose) at two concentrations. Fungal communities were impacted more strongly than bacterial communities by carbon inputs under simulated urine patch conditions and had more variable responses among taxa. The richness of Chytridiomycota and Glomeromycota were most negatively affected, and Tremellomycetes most positively affected, by carbon inputs. A minority of fungal ASVs had greatly increased abundances in response to carbon, while fungal trophic composition became highly dominated by saprotrophs by the experiment end. Bacterial taxa showed consistent trends of declining (to about 14 days) and recovering (to 112 days) richness in response to urine and carbon inputs, but carbon-related evenness and abundance trends varied between taxa. Actinobacteria, Bacteroidetes, Betaproteobacteria, and Gammaproteobacteria each increased in abundance in response to carbon, whereas Acidobacteria, candidate division WPS-1, Planctomycetes, Deltaproteobacteria, and Verrucomicrobia each decreased in abundance. These results show that labile carbon inputs to limit nitrogenous leaching support the resilience of prokaryote communities to bovine urine events but may have long-term impacts on fungal community composition and function, with potential consequences for soil food webs, carbon sequestration, and agricultural productivity.
Identification of the potential cytokines involved in LPS induced acute lung injury in mouse
Authors: Qing Jiayue , Zhou Hongmei , Hu Li , Zhu Zhipeng
Published: September 2022

To identify the differentially expressed genes encoding promising inflammatory cytokines in murine lungs in the context of acute lung injury (ALI). Through searching the Gene Expression Omnibus (GEO) databases, three GEO datasets were identified based on the LPS induced animal model within 24hr, differentially expressed genes (DEGs) were extracted and analyzed with R studio, the properties of those DEGs were further analyzed by Protein-Protein-Interaction (PPI), Cytoscape, GO and KEGG bioinformatics techniques as well. The potential hub genes in inflammatory related cluster were retrieved and examined furthermore by basal experiments. By searching, GSE1871, GSE104214, and GSE130936 were screened with a priority of animal model formed in less than 24hr. With a criterion of |log2 fold change (FC)| ≥ 2 and an adjusted P-value < 0.01, 923 DEGs were found altogether in three datasets, eventually 87 overlapped genes were achieved commonly. Most of those DEGs come from anchored component of basal membrane and modulate the cytokine-receptors activity, participating in the regulation of responses to cellular stimuli or cytokine-mediated signaling pathways. Through bioinformatics techniques, 2 clusters were separated by K- means algorithm in 87 DEGs, 20 ranked hub genes were finally concluded. The GO and KEEG enrichment analysis of these 20 genes were highly consistent with previous results except that these hub genes are involved in both virus-related and LPS-related biological processes. For LPS induced in vivo experiment, 7 out of 20 genes exhibited mRNA overexpression under cytokine-cytokine receptors interaction pathway, having a more probability to function in inflammation-related cytokine signaling judging from the predicted transcription factor. Altogether, these findings find out some potential DEGs involved in virus and inflammation related biological process, identified 7 potential hub genes could be the therapeutic target on the cytokine-receptor interaction pathway ground in LPS induced ALI.
Evaluation of metal exposure through the composition of essential and toxic micro-minerals in freshwater turtles (Phrynops geoffroanus) from a Brazilian river
Authors: Fonseca Cristina Farias da , Silva Iago José Santos da , Rodrigues Midiã da Silva , Silva Bruna Higino de Souza , Soares Pierre Castro , de Moura Geraldo Jorge Barbosa , de Oliveira Jaqueline Bianque
Published: September 2022

This study aimed to evaluate the metal exposure through the concentration of essential and toxic micro-minerals in biological samples of Phrynops geoffroanus from an anthropized river. The work was carried out in four areas with different flow characteristics and uses of the river, where individuals of both sexes were captured during the dry and rainy seasons. The elements Al, Cd, Co, Cr, Cu, Fe, Mn, Mo, Ni, Pb, and Zn, were quantified in samples of serum (168), muscle (62), liver (61), and kidney (61) by Inductively Coupled Plasma Optical Emission Spectrometry. The concentration of the elements varied according to the sample type, being higher in the liver and the kidney. In the serum, many elements were below the limit of quantification, but it was possible to determine Al, Cu, Fe, Mn, Pb, and Zn. The liver showed high levels of Cu, Fe, and Pb, and muscle for Ni, Pb, and Zn, with most of the elements accumulated in the kidney tissue (Al, Cd, Co, Cr, Mn, Mo, and Ni). There was no significant difference between sex in the accumulation of elements. Between seasons, Cu was higher in serum and Mn in muscle and liver in the dry period, while in the kidney, almost all the elements were higher in the rainy period. The concentrations of the elements in the samples indicated a high degree of environmental contamination, representing risk in the use of the river and consumption of food from local fisheries.
Surrogate "Level-Based" Lagrangian Relaxation for Mixed-Integer Linear Programming
Authors: Bragin Mikhail , Tucker Emily
Published: September 2022

Mixed-Integer Linear Programming (MILP) plays an important role across a range of scientific disciplines and within areas of strategic importance to society. The MILP problems, however, suffer from combinatorial complexity. Because of integer decision variables, as the problem size increases, the number of possible solutions increases super-linearly thereby leading to a drastic increase in the computational effort. To efficiently solve MILP problems, a “price-based” decomposition and coordination approach is developed to exploit 1. the super-linear reduction of complexity upon the decomposition and 2. the geometric convergence potential inherent to Polyak’s step-sizing formula for the fastest coordination possible to obtain near-optimal solutions in a computationally efficient manner. Unlike all previous methods to set step-sizes heuristically by adjusting hyper-parameters, the key novel way to obtain step-sizes is purely decision-based: a novel “auxiliary” constraint satisfaction problem is solved, from which the appropriate step-sizes are inferred. Testing results for large-scale Generalized Assignment Problems (GAP) demonstrate that for the majority of instances, certifiably optimal solutions are obtained. For stochastic job-shop scheduling as well as for pharmaceutical scheduling, computational results demonstrate the two orders of magnitude speedup as compared to frequently used Branch-and-Cut (B&C). SLBLR has a major impact on the efficient resolution of complex Mixed-Integer Programming (MIP) problems arising within a variety of scientific fields.
Single-Stage Isolation of Pure Andrographolide from Andrographis Paniculata in a Moderately Polar Solvent byOptimizing Different Parameters
Authors: MAURYA RAHUL , B Thirupataiah , Misro Lakshminarayana , R Thulasi , VR Rajeesh , KS Rohit
Published: September 2022

The primary objective of the proposed research work is to extract and enrich pure andrographolide (AGL) by varying the polarity index and Hildebrand solubility parameter (δ) of a moderately polar solvent. Both parameters affect the solubility of AGL in different solvents and extraction methods. AGL was extracted from the whole plant Andrographis paniculata. Continuous or Direct, Maceration and Soxhlet extraction method used for extraction. Based on the appearance of the crystal in the direct Soxhlet ethyl acetate method, their yield was further optimized by using a randomized response surface (RSM) and quadratic model-based Box‒Behnken design (BBD). HPTLC was used to determine the AGL extraction efficiency, purity, and quantification. Based on the obtained result, the pure andrographolide crystal (yield 0.185 g/g) was obtained by direct Soxhlet extraction. Ethyl acetate is used as a solvent. The Rf exhibited in the TLC chromatogram was 0.28. The FT-IR spectra exhibited characteristic peaks similar to the standard AGL, and 1H-NMR and 13C NMR elucidated the crystal structure. The DEPT − 90/135 spectra showed that the extracted crystal was pure AGL. One of the novel approaches is isolating pure AGL crystals in a moderately polar solvent (ethyl acetate) by elevating the Hildebrand solubility parameter despite using polar solvents. AGL crystals were obtained from direct Soxhlet extraction by ethyl acetate. It is a single-step and more economical method. It can be easily transformed into a pilot or industrial setup to extract the pure AGL.
Effect of model resolution on simulation of tropical cyclone landfall in East Asia based on a comparison of 25- and 50-km HiRAMs: Role of monsoon flow–topography interaction
Authors: Chen Kuan-Chieh , Tsou Chih-Hua , Hong Chi-Cherng , Hsu Huang-Hsiung , Tu Chia-Ying
Published: September 2022

The effect of model resolution on the simulation of tropical cyclone (TC) landfall frequency in East Asia (including the South China Sea [SCS], Taiwan and coastal areas of East China [TWCN] and Japan [JP]) was investigated by comparing Atmospheric-Model-Intercomparison-Project-type simulations on the basis of 50-km High Resolution Atmospheric Models (HiRAMs) and 25-km HiRAM. The number of TC landfalls in the TWCN region was realistically simulated by the 50-km HiRAM ensemble model. However, fewer (more) TCs were steered westward (northward) toward the SCS (JP) because of an overestimation of the monsoon trough in the western North Pacific (WNP). The overestimation created a low-level cyclonic circulation anomaly in the WNP, which substantially modified steering flow. Consequently, more (less) TC made landfall in JP (SCS). The overestimation of the monsoon trough was due to an underestimation of the monsoon flow–topography interaction in the Indochina Peninsula Mountains; specifically, the underestimation produced an anomalous east–west overturning circulation in the Indochina Peninsula–WNP, which caused the ascending branch in the WNP to favor convection and strengthened the monsoon trough. The underestimation of the monsoon flow–topography interaction in the Indochina Peninsula Mountains was improved substantially by increasing the model’s horizontal resolution with the 25-km HiRAM. The improvement in the monsoon flow–topography interaction further reduced the overestimation of the WNP monsoon trough, number of TC geneses, and track frequency.
Dual spaces for weak martingale Hardy spaces associated with rearrangement-invariant spaces
Authors: Silas Niyonkuru , Xie Guangheng
Published: September 2022

Given a probability space $(\Omega,\mathcal{F},\mathbb P)$ and a rearrangement-invariant quasi-Banach function space $X$, the authors of this article first prove the $\alpha$-atomic ($\alpha\in [1,\infty)$) characterization of weak martingale Hardy spaces $WH_X(\Omega)$ associated with $X$ via simple atoms. The authors then introduce the generalized weak martingale ${\rm BMO}$ spaces which proves to be the dual spaces of $WH_X(\Omega)$. Consequently, the authors derive a new John--Nirenberg theorem for these weak martingale ${\rm BMO}$ spaces. Finally, the authors apply these results to the generalized grand Lebesgue space and the weighted Lorentz space. Even in these special cases, the results obtained in this article are totally new.
Comparing RNA extraction methods to face the variations in RNA quality using two human biological matrices.
Authors: Ortega-Pinazo Jesús , Serrano-Castro Pedro Jesús , Martínez Beatriz , Pinto-Medel María Jesús , Gómez-Zumaquero Juan Miguel , Lago-Sampedro Ana , García-Díaz Beatriz , Arrabal-Ayala María , Estivill-Torrús Guillermo , Ferro Pedro
Published: September 2022

Nucleic acids, RNA among them, are widely used in biomedicine and biotechnology. Because of their susceptibility to degradation by RNases, the handling and extraction process of RNA from cells and tissues require specialized personnel and standardized methods to guarantee high purity and integrity. Due to the diversity of techniques found in the market, a comparative study between different RNA extraction methods is useful to facilitate the best choice for the researcher or in research service platforms such as biobanks to see the traceability of the samples. In this study, we have compared seven different RNA extraction methods: manual (TRIzol™), semiautomated (QIAGEN™, Bio-Rad, Monarch®, and Canvax™), and fully automated (QIAcube™ and Maxwell®) processes, from two biological matrices: human Jurkat T cells and peripheral blood mononuclear cells (PBMC). Results showed marked differences in the RNA quality and functionality according to the method employed for RNA extraction and the matrix used. These data contribute to facilitating researchers or research service platforms in decision-making practices and emphasize the relevance of the selection of the RNA extraction method in each experimental procedure or traceability study to guarantee both quality standards and its reproducibility.
Economic Analysis of Grafted Organic Tomato Production in High Tunnels
Authors: Nian Yefan , Zhao Ruojin , Tian Shufang , Zhao Xin , Gao Zhifeng
Published: September 2022

With the phase-out of methyl bromide because of its impact on ozone depletion and the shift to a more protected culture system in organic vegetable production, grafting practice has gained greater attention in the United States because it may be considered a viable disease control method in organic vegetable production. However, there is a lack of information on the economic feasibility of using grafting in organic tomato (Solanum lycopersicum) production in a protected culture system such as a high-tunnel system. Using 2-year on-station trial data collected in Citra, FL, we examined the effect of using grafting on the economic returns of organic tomato production in high tunnels. Our analysis suggests that grafting tends to increase the marketable yield of organic tomato production in high tunnels. However, the enhanced yield does not necessarily increase the net return, depending on market conditions and the relative performance of grafted transplants. In addition, our results indicate that the net return of grafted production is highly sensitive to the tomato selling price. Obtaining a price premium is essential for increasing the profitability of grafted organic tomato production in high tunnels.
Phenomenology of Digital Academic Dishonesty at University
Authors: Klopkova Elizaveta , Miklyaeva Anastasiya
Published: September 2022

The article describes the phenomenology of academic dishonesty in offline and online learning. The authors developed a questionnaire to assess the occurrence of various types of cheating, students’ subjective attitude to academic dishonesty, and its context. The study involved 52 university students aged 18–25 (37 female respondents). The obtained data were subjected to statistical analysis using the G-criterion and the Fisher’s angular transformation. The content analysis consisted of questions that required an extended answer. In online environment, the most common form of academic dishonesty was cheating at exams and tests by copying a fellow student's digital work, imitating technical problems, googling for answers, and providing false references. Students treated online academic dishonesty as more acceptable than during face-to-face learning. The study proves that the phenomenology of online academic dishonesty is significantly different from its traditional variant and, therefore, requires more detailed research.
What does God know? Treatise on the “divine knowledge” in the structure of natural theology by Francisco Suárez
Authors: Ivanov Vitaly L.
Published: September 2022

The article is a study of the late scholastic concept of natural theology based on the works of Fr. Suárez, Metaphysical Disputations (1597) and De Deo Uno et Trino (1607), as well as the analysis of the treatise on “divine knowledge” and the demonstration of its significance in the structure of Suárez’s natural theology. First, the article explicates the concept of natural theology as the highest and most noble part of metaphysical science, since the natural theology of Suárez differs both from supernatural or revelation theology, and from the whole metaphysical knowledge about being. Second, the thematic content of natural theology is described in comparison with revelation theology, and the general method of natural theology, which is determined by the specific limitations of the natural knowledge of God in this life, is analyzed. At the same time, the most important role of the traditional scholastic concept of “perfectio simpliciter” as revealing the essence of Suárez’s method in natural theology is emphasized. Third, we point out the reasons for the special significance of the treatise on the “divine knowledge/scientia Dei” contained in section 15 of Suárez’s 30th Metaphysical disputation, and analyze the structure of this treatise, showing how Suárez’s exposition in it corresponds to the general “rule of method”. Fourth, the article thematizes the question of the objects of knowledge of the divine intellect, explains the general division of objects into three classes and explicates the complex type of connection between the cognition of the primary and secondary objects of the divine intellect, since it determines the way God knows finite possible things “in themselves”. Finally, we show a certain ambivalence in Suárez’s understanding of the reality and objectivity of the objective being (esse obiectivum) of possible finite essences as a secondary object that terminates divine knowledge.
Effect of sponge city construction on urban waterlogging reduction in semi-humid areas of China
Authors: Wang Mengjie , Lu Yiyun , Ge Xiaoyu
Published: September 2022

Urban waterlogging frequently occurs in semi-humid areas due to the short duration of heavy rainfall in summer and the high rates of subsurface hardening caused by high-intensity urban development. To solve the problem of urban waterlogging, China has launched the construction of ‘sponge cities’ and made some progress, but there is still a lack of comprehensive consideration of the functional types and spatial layout of low impact development (LID) facilities. Qian'an, a city of Hebei Province, is one of the first sponge city pilot cities in China. This paper focuses on Yanshan South Road and its surrounding areas, a historical waterlogging section of Qian'an city. Four common LID measures (sunken green space (SG), bioretention ponds (BP), infiltration ponds (IP), and reservoirs (RE)) in two function types are selected and combined through centralized (CE) and decentralized (DE) different spatial layouts, a total of 80 design scenarios are proposed. Then, using the storm water management model (SWMM) to calculate the effect of each scheme on peak flow reduction under different rainfall return periods. The results showed that all LID scenarios can effectively alleviate the urban waterlogging problem, among which the schemes of DE-SG-BP (1:1), DE-IP-SG (1:1), DE-SG-IP (3:1), DE-SG-IP (1:3), and DE-SG-BP (3:1) had the highest peak flow reduction rate, up to 95.46%. The schemes of CE-RE-IP (3:1) and CE-IP-RE (3:1) had better hydrological performance in occupying less surface space, with a peak flow reduction rate of 8.68% per square meter. Therefore, the distributed layout combined with infiltration LID facilities and storage LID facilities can be used in urban built-up areas with limited land use conditions, which has a more obvious effect on reducing waterlogging.
Analysis of runoff variation and driving factors in the Minjiang River Basin over the last 60 years
Authors: Zhai Hongjuan , Wang Meng , Shen Dandan , Hu Bo , Li Yajun
Published: September 2022

An absolute essential for effective water resource management and ecological restoration is knowing the temporal and spatial variation of runoff. The objective of this study was to determine the spatial and temporal changes in runoff at the main hydrological stations along the Minjiang River and the Dadu River between 1961 and 2016 using the non-parametric Mann-Kendall test and annual variation analysis. Canonical correspondence analysis and regression analysis were used to determine the contribution of anthropogenic disturbance, vegetation, and climatic conditions to runoff change. The runoff at each station of the Minjiang River showed a clear decreasing trend, whereas the decreasing trend of the Dadu River was not significant. Moreover, the discharge at the Shawan (SW) station upstream of the Dadu River and the Gaochang (GC) station downstream of the Minjiang River have changed significantly during the flood and non-flood seasons since 2000, while the discharge at other stations has not changed significantly. The average annual runoff in the non-flood season at SW and GC in 2011–2016 increased by approximately 26.21 and 36.47%, respectively, compared with 1961–2010. Anthropogenic disturbance, vegetation, and climatic conditions in the Minjiang River Basin accounted for 76.24, 13.62, and 10.14%, respectively, of the runoff change in the basin. Water consumption and total reservoir capacity were the specific factors most affecting runoff change in the basin, accounting for 15.10 and 13.94%, respectively, of the changes in runoff. The research can provide important support for the ecological restoration of Minjiang River Basin and Yangtze River Basin.
NMDA-Receptor Channel Blocker Heterogeneity
Authors: Harris E.W. , Murray R.J.
Published: September 2022

A number of antagonists of the NMDA-selective ionotropic glutamate receptor have been synthesized and evaluated in animals and in man. Several compounds that bind to the "MK-801 site" within the NMDA-receptor channel have been tested in animals, and some in man. Although these compounds have a common pharmacological action, there are surprising differences in the safety profiles within this single class of NMDA-antagonists. The reasons for this heterogeneity are unclear, but may result from preferential selectivity for different NMDA-receptor subtypes, of which there are many, differences in the kinetics of NMDA-receptor block, or possibly the existence of multiple modes of channel block. These issues, possible underlying structural correlates, and prospects for being able to optimize NMDA channel blockers with regard to their safety profile are discussed.
Circuit bodyweight training: does it affect increasing arm muscle endurance and archery accuracy in pandemic conditions?
Authors: Yachsie Betrix Teofa Perkasa Wibafied Billy , Suharjana Suharjana , Wijaya Ridho Gata , Nasrulloh Ahmad
Published: September 2022

Restrictions on community activities due to the spread of the Covid-19 virus have changed sports in Indonesia, forcing athletes to practice independently in their respective homes with training programs created by coaches. This study aims to find out the effect of circuit body weight training on arm muscle endurance and archery accuracy of archery athletes. This research is an experimental method of one group pretest-posttest design. This study employed purposive sampling with the criteria of elite archery athletes, still in high school, male, and willing to participate. Total of 12 athletes was given treatment with 8 movements for 16 meetings. The instrument is a holding bow digit test for arm muscle endurance, while archery accuracy uses 50 meters of archery. The collected data were examined for normality and homogeneity, then followed with t-test with the result that t count = 0.00 less than t (0.05). Based on the results, it is concluded that circuit bodyweight training positively improves arm muscle endurance and accuracy of archery athletes. Therefore, giving circuit bodyweight training can be used as a recommendation for physical exercise to increase arm muscle endurance and archery accuracy in archery athletes.
Оптические метки на основе золотых нанозвёзд для ГКР-картирования тканей с использованием красных медицинских лазеров
Authors: Свинко В.О. , Шевчук А.И. , Смирнов А.Н. , Макеева Д.В. , Соловьева Е.В.
Published: September 2022

Star-shaped gold nanoparticles modified with cyanine 5.5 derivatives were studied as optical tags for bioimaging by surface-enhanced Raman scattering (SERS). Obtained tags showed a plasmon resonance band at 640 nm in the absorption spectra which ensures them a maximum efficiency when excited by red lasers. SERS measurements were carried out for the modified particles in the solution phase and after incubation with the PANC-1 cell line. The SERS spectra of the solutions revealed a characteristic signal of cyanine 5.5 amino derivative in the range of 100–1000 cm–1, where there is no high fluorescent background. In cell samples, the SERS spectrum of the dye was recorded from the cytoplasm and was not detected outside the cells. In order to confirm the intracellular localization of the tags, the SERS spectra were also scanned in height. The test on cytotoxicity showed that the studied tags are not toxic in the concentration range from 0.05 to 1 mg/l on atomic gold.
Effectiveness of eHealth Self-management Interventions in Patients With Heart Failure: Systematic Review and Meta-analysis
Authors: Liu Siru , Li Jili , Wan Ding-yuan , Li Runyi , Qu Zhan , Hu Yundi , Liu Jialin
Published: September 2022

Background

Heart failure (HF) is a common clinical syndrome associated with substantial morbidity, a heavy economic burden, and high risk of readmission. eHealth self-management interventions may be an effective way to improve HF clinical outcomes.

Objective

The aim of this study was to systematically review the evidence for the effectiveness of eHealth self-management in patients with HF.

Methods

This study included only randomized controlled trials (RCTs) that compared the effects of eHealth interventions with usual care in adult patients with HF using searches of the EMBASE, PubMed, CENTRAL (Cochrane Central Register of Controlled Trials), and CINAHL databases from January 1, 2011, to July 12, 2022. The Cochrane Risk of Bias tool (RoB 2) was used to assess the risk of bias for each study. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) criteria were used to rate the certainty of the evidence for each outcome of interest. Meta-analyses were performed using Review Manager (RevMan v.5.4) and R (v.4.1.0 x64) software.

Results

In total, 24 RCTs with 9634 participants met the inclusion criteria. Compared with the usual-care group, eHealth self-management interventions could significantly reduce all-cause mortality (odds ratio [OR] 0.83, 95% CI 0.71-0.98, P=.03; GRADE: low quality) and cardiovascular mortality (OR 0.74, 95% CI 0.59-0.92, P=.008; GRADE: moderate quality), as well as all-cause readmissions (OR 0.82, 95% CI 0.73-0.93, P=.002; GRADE: low quality) and HF-related readmissions (OR 0.77, 95% CI 0.66-0.90, P<.001; GRADE: moderate quality). The meta-analyses also showed that eHealth interventions could increase patients’ knowledge of HF and improve their quality of life, but there were no statistically significant effects. However, eHealth interventions could significantly increase medication adherence (OR 1.82, 95% CI 1.42-2.34, P<.001; GRADE: low quality) and improve self-care behaviors (standardized mean difference –1.34, 95% CI –2.46 to –0.22, P=.02; GRADE: very low quality). A subgroup analysis of primary outcomes regarding the enrolled population setting found that eHealth interventions were more effective in patients with HF after discharge compared with those in the ambulatory clinic setting.

Conclusions

eHealth self-management interventions could benefit the health of patients with HF in various ways. However, the clinical effects of eHealth interventions in patients with HF are affected by multiple aspects, and more high-quality studies are needed to demonstrate effectiveness.
Study the Effect of Cutting Parameters on Temperature Distribution and Tool Life During Turning Stainless Steel 316L
Authors: Akbar Ahmed A. , Shwaish Raed R. , Hadi Naba D.
Published: September 2022

This paper is focused on studying the effect of cutting parameters (spindle speed, feed and depth of cut) on the response (temperature and tool life) during turning process. The inserts used in this study are carbide inserts coated with TiAlN (Titanum, Aluminium and Nitride) for machining a shaft of stainless steel 316L. Finite difference method was used to find the temperature distribution. The experimental results were done using infrared camera while the simulation process was performed using Matlab software package. The results showed that the  maximum difference between the experimental and simulation results was equal to 19.3 , so, a good agreement between the experimental and simulation results  was achieved. Tool life was decreased when spindle speed and feed were increased.
Research Hotpots and Trends of Ideological and Political Education Work of Communist Youth League in High Schools -- Analysis of Cite Space Based on CNKI Database
Authors: Xu Didi
Published: September 2022

The paper analyzed 355 papers on “Youth League of Universities” in China Knowledge Network (CNKI) from 2012 to 2022 by using Cite Space knowledge visualization analysis tool. The results show that “Youth League”, “new media” and “higher vocational colleges” have become the hotpots of research in this field for more than ten years, and the number of papers has been influenced by the policy. The number of papers has shown a wave development trend from decreasing to increasing, and then decreasing to increasing again; the frontier areas of research are “second classroom”, “collaborative education”, “new era”, “thought leadership”, and “new era”. Compared with the work of ideological and political education in colleges and universities and the work of the Communist Youth League in colleges and universities, the research results related to the ideological and political education work of the Communist Youth League in colleges and universities are fewer and of higher quality. Compared with the work of ideological and political education in colleges and universities and the whole work of the Communist Youth League in colleges and universities, the research results related to the work of the Communist Youth League in colleges and universities are less and of lower quality. By analyzing the current development trend and hot spots of the ideological and political work of the Communist Youth League in colleges and universities, we pay attention to the work of the Communist Youth League in colleges and universities, accurately grasp the positioning of the Communist Youth League in the ideological and political education work, further improve the ideological and political education level of the Communist Youth League in colleges and universities, and the systematic implementation mechanism of the ideological and political education work of the Communist Youth League in colleges and universities.
Colloquial Crumbs: Reclamation of Spaces in Food and Memory in Sara Suleri’s Meatless Days
Authors: Das Priyanjana
Published: September 2022

Autobiographical narratives—in the form of travelogues, memoirs, diaries, and other personal accounts—are crucial literary interventions that have aided a global and cosmopolitan expansion. Such self-narrations, excavating the lives of writers, elucidate and explore various cultural associations within society. Moreover, as the process of self-narration and the creation of an identity progresses, autobiographies, cumulatively known as ‘life-writing’ since 1990, essentially highlights the differences between the public and the private self, which gives rise to a tendency to marginalise the woman writer—who is often characterised by an ambiguous existence in the public domain. My paper will explore this idea of self-reflection and self-discovery in its attempt to situate Sara Suleri’s memoir Meatless Days (1989) within the postcolonial female identity, thereby unravelling the domestic space as a crucially inventive and creative space for the reclamation of the identity of a writer. The relationship of the domestic space with metaphors of food significantly emerges as a unifying trajectory to an imaginative home/land in turmoil. It forms a site emblematic of cultural identity and critical contentions in the ways in which they were presented and represented, beginning to allow an efflorescence of not only an aesthetic imagination of the domestic space but also a way of reclaiming it. Essentially, through an analysis of the memory and food and consumption metaphors (often extending out to be the feminine domestic space) that Suleri significantly uses in her narrative, this paper will explore facets of identity creation and continuity as a counter-narrative of patriarchal nation-building against the backdrop of ongoing political turmoil.
Фильтр, согласованный с аберрациями, для анализа топологического заряда вихревого пучка
Authors: Хорин П.А. , Хонина С.Н.
Published: September 2022

Известно, что для анализа топологического заряда вихревого пучка используется астигматическое преобразование. В данной работе для осуществления астигматических преобразований вихревых пучков используется многоканальный фильтр, согласованный с различными аберрациями, описываемыми полиномами Цернике. Такой фильтр позволяет внести в анализируемый вихревой пучок сразу несколько волновых аберраций различного типа и уровня для осуществления различных аберрационных преобразований, включая астигматизм. При этом в фокальной плоскости в различных дифракционных порядках формируется набор аберрационно-преобразованных распределений анализируемого вихревого пучка, что облегчает определение его топологического заряда.