bluuebunny/crossref_metadata_2025 huggingface dataset:
Methoxylated Flavonols and ent-Kaurane Diterpenes from the South African Helichrysum rutilans and Their Cosmetic Potential
Authors: Popoola Olugbenga K. , Marnewick Jeanine L. , Iwuoha Emmanuel I. , Hussein Ahmed A.
Published: August 2023

Chromatographic fractionation of a methanol extract of Helichrysum rutilans afforded seven known compounds. The isolated compounds were identified as 5,7,8-trihydroxy-3,6-dimethoxyflavone-8-O-2-methyl-2-butanoate (C-1), 5,7-dihydroxy-3,6,8-trimethoxyflavone (C-2), 5-hydroxy-3,6,7,8-tetramethoxyflavone (C-3), 5-hydroxy-3,6,7-trimethoxyflavone (C-4), ent-kaurenoic acid (C-5), ent-kauran-18-al (C-6), and 15-α-hydroxy-(-)-ent-kaur-16-en-19-oic acid (C-7). Compounds C-1–C-4 demonstrated high antioxidant capacities on ORAC hydroxyl radical (2.114 ± 4.01; 2.413 ± 6.20; 1.924 ± 16.40; 1.917 ± 3.91) × 106; ORAC peroxyl radical (3.523 ± 3.22; 2.935 ± 0.13; 2.431 ± 8.63; 2.814 ± 5.20) × 103 µMTE/g; and FRAP (1251.45 ± 4.18; 1402.62 ± 5.77) µMAAE/g, respectively. Moderate inhibitory activities against Fe2+-induced lipid peroxidation were observed for C-1–C-4 as IC50 values of 13.123 ± 0.34, 16.421 ± 0.92, 11.64 ± 1.72, 14.90 ± 0.06 µg/mL, respectively, while their respective anti-tyrosinase activities with IC50 values of 25.735 ± 9.62, 24.062 ± 0.61, 39.03 ± 13.12, 37.67 ± 0.98 µg/mL were also observed. All compounds demonstrated TEAC values within the range of 1105–1424 µMTE/g. The result is an indication that a methanol extract of H. rutilans might possibly be a good source of natural antioxidants against ailments caused by cellular oxidative stress and as inhibitors against skin depigmentation, as well as possible raw materials needed for slowing down perishable agricultural products. This is the first report on the phytochemical and biological evaluation of H. rutilans.
Fabrication of a Charge-Conversion Polymer—Liposome for Enhancing Endosomal Escape of Drug Delivery System for α–Mangostin
Authors: Phan Trang Thi Kieu , Nguyen Hoang Huy , Nguyen Xuan Thi , Van Nguyen Tung , Duong Linh Anh , Nguyen Linh Phuong , Pham Uyen Thu , Le Hong Nhung , Tran Toan Quoc , Nguyen Duong Thanh , Pham Dung Thuy Nguyen
Published: August 2023

α–Mangostin, which is a natural xanthone compound, inhibits the metastasis and survival of various cancer cell types. However, its therapeutic effectiveness is limited by low water solubility and very poor absorption. There are several studies that developed the drug delivery system for α–mangostin, but they are still a remaining challenge. Drug delivery techniques are severely hampered by the breakdown of nanoparticles inside endosomes. The abrasive chemical environment in these compartments causes both the nanoparticles and the encapsulated α–mangostin to degrade throughout the course of the voyage. Intracellular defenses against external materials refer to this collective mechanism. A pH-responsive liposome named PAsp(DET-Cit)–Toc, made of lipids and a charge-conversion polymer (CCP), has been created for the targeted transport of α–mangostin in order to avoid this deteriorative outcome. The average hydrodynamic size of CCP–liposome particles is 98.59 ± 5.1 nm with a PDI of 0.098 ± 0.02 and a negative zeta potential of 22.31 ± 2.4 mV. TEM showed the shape of the spherical CCP–liposomes. α–Mangostin is successfully captured inside CCP–liposome and the loading yield reached the highest encapsulation efficiency of 83% with 150 μg/mL of α–mangostin. In the acidic condition of pH 5.0, an initial burst of α–mangostin reached 50% after 6 h in buffer solution. CCP–liposomes could escape from endosomes even after 3 h, and almost 80% of CCP–liposomes escaped after 24 h. The cell ability of α–mangostin-loaded-CCP–liposome incubated in buffer solutions of 5.0 decreased significantly and was close to free α–mangostin. Our data proved that α–mangostin-loaded CCP–liposome delivered more effectively α–mangostin into cells and prevented the degradation of α–mangostin inside cells, especially endosomal degradation.
“Digital Resources Are Not Reliable”: Peer-Group-Based Intellectualism among Muslim Youth Activists in Bima, Eastern Indonesia
Authors: Wahid Abdul , Wardatun Atun
Published: August 2023

This article explores the sources of Islamic knowledge among young Muslim activists in Bima, Eastern Indonesia, who are often stereotyped as a hotbed of radicalism, and their religious types to reveal their intellectual dynamics. This article argues that, in modern times, as Islamic tendencies and orientations have diversified, young Muslims in the Bima region engage with many different aspects of the production and use of religious knowledge under the umbrella of Indonesian Islam. Moreover, they actively build peer-group-based intellectualism, fostering patron–client connections in the form of discussion and literacy development through student organizations, and this is influential in shaping their religious identities and religious types. This qualitative research involved 47 young Muslim activists, who are also senior high school and university students, 20 of whom were interviewed in-depth, while 27 others participated in focus group discussions. This research reveals that their sources of learning vary. However, the most critical media in shaping and confirming their religious understanding are the training and discussions held by their respective peer groups and organizations. Their literacy and references are also further developed through these forums. Learning resources accessed via social media are considered essential but unreliable in this digital era. Therefore, in their intellectual development, young persons need teachers and families to act as learning resource providers that co-exist with the literacy obtained through organizations. Such sources and ways of learning form a type of religiosity that is “practical” (embodied in daily practice) for most. Meanwhile, the “ideological” type of religion (fundamental to the Islamization movement) is only found in right-wing activists of Islamic organizations and does not thrive among the young people of Bima, Eastern Indonesia.
Target Detection of Passive Bistatic Radar under the Condition of Impure Reference Signal
Authors: Wu Yong , Chen Zhikun , Peng Dongliang
Published: August 2023

This paper addresses the issue of the reference signal being contaminated by target echoes due to factors such as wide beamwidths, beam pointing errors, or site errors in passive bistatic radar (PBR). Such contamination can lead to reference signal impurity and subsequently degrade the performance of traditional object detection methods. To overcome this challenge, a novel target detection method centered around the reference signal’s purification is presented. The proposed method involves the modeling, analysis, localization, and purification of the impure reference signal. First, a new signal model incorporating the impure reference signal is established, followed by a comprehensive analysis of its impact on target detection. Then, leveraging the valuable information hidden in the impure reference signal, target echoes within the impure reference signal are localized and reconstructed. Finally, the reconstructed target echoes are subtracted from the original impure reference signal to purify the reference signal. Based on the purified reference signal, traditional target detection is performed to detect the expected targets. The core advantage of this method lies in its efficient reconstruction and removal of the impure terms within the reference signal. The effectiveness of the proposed method is demonstrated through a series of simulation results.
Dynamic Sensorless Control Approach for Markovian Switching Systems Applied to PWM DC–DC Converters with Time-Delay and Partial Input Saturation
Authors: Zahaf Abdelmalek , Bououden Sofiane , Chadli Mohammed , Boulkaibet Ilyes , Neji Bilel , Khezami Nadhira
Published: August 2023

This paper provides a detailed analysis of the output voltage/current tracking control of a PWM DCDC converter that has been modeled as a Markov jump system. In order to achieve that, a dynamic sensorless strategy is proposed to perform active disturbance rejection control. As a convex optimization problem, a novel reformulation of the problem is provided to compute optimal control. Accordingly, necessary less conservative conditions are established via Linear Matrix Inequalities. First, a sensorless active disturbance rejection design is proposed. Then, to carry out the control process, a robust dynamic observer–predictive controller approach is introduced. Meanwhile, the PWM DC-DC switching power converters are examined as discrete-time Markovian switching systems. Considering that the system is subject to modeling uncertainties, time delays, and load variations as external disturbances, and by taking partial input saturation into account, the Lyapunov–Krasovskii function is used to construct the required feasibility frame and less conservative stability conditions. As a result, the proposed design provides an efficient control strategy with disturbance rejection and time-delay compensation capabilities and maintains robust performance with respect to constraints. Finally, a PWM DC-DC power converter simulation study is performed in different scenarios, and the obtained results are illustrated in detail to demonstrate the effectiveness of the proposed approach.
Battery Testing and Discharge Model Validation for Electric Unmanned Aerial Vehicles (UAV)
Authors: Di Nisio Attilio , Avanzini Giulio , Lotano Daniel , Stigliano Donato , Lanzolla Anna M. L.
Published: August 2023

Electrical engines are becoming more common than thermal ones. Therefore, there is an increasing interest in the characterization of batteries and in measuring their state of charge, as an overestimation would cause the vehicle to run out of energy and an underestimation means that the vehicle is running in suboptimal conditions. This is of paramount importance for flying vehicles, as their endurance decreases with the increase in weight. This work aims at finding a novel empirical model for the discharge curve of an arbitrary number of battery pack cells, that uses as few tunable parameters as possible and hence is easy to adapt for every single battery pack needed by the operator. A suitable measurement setup for battery tests, which includes voltage and current sensors, has been developed and described. Tests are performed on both constant and variable power loads to investigate different real-world scenarios that are easy to reproduce. The main achievement of this novel model is indeed the ability to predict discharges at variable power based on a preliminary characterization performed at constant power. This leads to the possibility of rapidly tuning the model for each battery with promising accuracy. The results will show that the predicted discharged capacities of the model have a normalized error below 0.7%.
Anomaly Detection in Multi-Wavelength Photoplethysmography Using Lightweight Machine Learning Algorithms
Authors: Baciu Vlad-Eusebiu , Lambert Cause Joan , Solé Morillo Ángel , García-Naranjo Juan C. , Stiens Johan , da Silva Bruno
Published: August 2023

Over the past few years, there has been increased interest in photoplethysmography (PPG) technology, which has revealed that, in addition to heart rate and oxygen saturation, the pulse shape of the PPG signal contains much more valuable information. Lately, the wearable market has shifted towards a multi-wavelength and multichannel approach to increase signal robustness and facilitate the extraction of other intrinsic information from the signal. This transition presents several challenges related to complexity, accuracy, and reliability of algorithms. To address these challenges, anomaly detection stages can be employed to increase the accuracy and reliability of estimated parameters. Powerful algorithms, such as lightweight machine learning (ML) algorithms, can be used for anomaly detection in multi-wavelength PPG (MW-PPG). The main contributions of this paper are (a) proposing a set of features with high information gain for anomaly detection in MW-PPG signals in the classification context, (b) assessing the impact of window size and evaluating various lightweight ML models to achieve highly accurate anomaly detection, and (c) examining the effectiveness of MW-PPG signals in detecting artifacts.
Spatial-Temporal Pattern and Driving Forces of Fractional Vegetation Coverage in Xiong’an New Area of China from 2005 to 2019
Authors: Huang Zhiqing , Qiu Haitao , Cao Yonggang , Gong Adu , Wang Jiaxiang
Published: August 2023

The Xiong’an New Area was officially established in 2018 to construct a new, intelligent, and efficient urban area to alleviate Beijing’s non-capital functions. Using Landsat satellite images, we employed the dimidiate pixel model, band operation, and transition matrix to analyze the temporal and spatial variations in FVC (Fractional Vegetation Coverage) within the Xiong’an New Area in 2005, 2013, and 2019, respectively. Urbanization rate, precipitation, temperature, and population were considered potential driving forces, which we analyzed using grey relational analysis and linear regression to explore the correlation between FVC and these factors. The findings are as follows: from 2005 to 2019, overall improvement and significant degradation have been observed. In Baiyangdian, a part of the national key ecological area, water bodies and FVC have increased. Grey relational analysis revealed that precipitation had the highest grey relational value of 0.76. The average correlation among natural factors was 0.67, while that among human factors was 0.60. Generally, the Xiong’an New Area vegetation exhibited instability, while Baiyangdian demonstrated relatively stable FVC. Grey relational analysis indicates a strong potential for social and economic development in the Xiong’an New Area.
Drivers of Engineering Procurement and Construction Model Adoption Behavior by Public Construction Owners in China
Authors: Wang Shaowen , Liu Xiaojun , Shao Weixing
Published: August 2023

The promotion of the EPC model in public construction projects is a priority for reform in the Chinese construction industry. This study integrates the push–pull–mooring (PPM) model with the stimulus-organism-response (SOR) framework to explore the influencing factors and action mechanisms of adopting the EPC model of the owners of public construction projects in China. An online questionnaire was sent to public construction project owners who have participated in EPC projects. Partial least squares-structural equation modeling (PLS-SEM) was employed to analyze the survey data. The results identified that the push factors for public construction project owners to the adoption of the EPC model include owners’ management ability, owner’s knowledge about EPC, and the matching degree between the owner’s management philosophy and EPC model; the pull factor is the performance pressure of the project; and the mooring factors include subjective norms, the maturity degree of the EPC, and the support environment. In addition, perceived usefulness, cognitive, and adoption attitude play a mediating role in the relationship between external stimuli and adoption behavior. Overall, this study enhances the understanding of Chinese public project owners’ behavior in adopting the EPC model and provides a theoretical basis for policy recommendations to promote the adoption of the EPC model by public construction project owners in China.
A Systematic Literature Review of Vehicle Routing Problems with Time Windows
Authors: Liu Xiaobo , Chen Yen-Lin , Por Lip Yee , Ku Chin Soon
Published: August 2023

Vehicle routing problems with time windows (VRPTW) have gained a lot of attention due to their important role in real-life logistics and transport. As a result of the complexity of real-life situations, most problems are multi-constrained and multi-objective, which increases their difficulty. The aim of this paper is to contribute to the effective solution of VRPTW-related problems. Therefore, research questions and objectives are set in accordance with PRISMA guidelines, and data extraction and analysis of the relevant literature within the last five years (2018–2022) are compared to answer the set research questions. The results show that approximately 86% of the algorithms involved in the literature are approximate methods, with more meta-heuristics than heuristics, and nearly 40% of the literature uses hybrid methods combining two or more algorithms.
Estimation of Fishery Losses from Great Cormorants during the Wintering Period in Greek Lagoons (Ionian Sea, W. Greece)
Authors: Katselis George , Konstas Spyridon , Moutopoulos Dimitrios K.
Published: August 2023

The present study aims through a modeling approach to quantify fishing losses from the impact of great cormorants (Phalacrocorax carbo sinensis) during their wintering period in Greek lagoons. A number of assumptions were incorporated into the model regarding fish population growth, species distribution, age (or size) of fish caught, and the different fishing strategies that could be applied in the studied lagoons. The results indicated that the mean value of daily economic losses ranged from 0.614 to 1.075 €·bird−1·day−1, whereas the ratios of biomass losses to landings biomass and of economic losses to economic profit ranged from 0.18:1 to 3.80:1 and from 0.14:1 to 4.18:1, respectively, depending on the lagoon. The results supported a strong competitive relationship between great cormorants and fisheries in lagoons of the Amvrakikos Gulf.
Barriers of Lean Accounting Implementation in Polish Enterprises: DEMATEL Approach
Authors: Stronczek Anna
Published: August 2023

Many manufacturing units make unsuccessful attempts to implement Lean Accountings in their management systems. Hence, such units must eliminate the prevailing lean accounting barriers to accomplish successful lean implementation. Moreover, the contextual relationship of lean accounting barriers must be studied to understand the effect of such barriers. The purpose of this study is to identify and analyze lean accounting implementation barriers. The analysis is going to determine how individual barriers interact to each other. The conclusions of this analysis are necessary for more effective implementation of lean accounting and moreover efficient lean management. The methodology consists of two stages. First it conducted literature review in order to identify barriers to implementing lean accounting in manufacturing companies. Then, analyzed connections between barriers using the DEMATEL method. The DEMATEL lean accounting barrier evaluation method helps companies better understand the barriers and their levels of importance in lean accounting implementation. Based on obtained results, it occurred that manufacturing companies should primarily address the issue of aversion to change to successfully implement lean accounting. This research supports managers in effectively implementing lean accounting in manufacturing companies by identifying implementation barriers and their interconnectedness. This exploratory study initiates a discussion on the barriers to implementing lean accounting in Polish enterprises and their mutual relations.
Neutralizing Activity against BQ.1.1, BN.1, and XBB.1 in Bivalent COVID-19 Vaccine Recipients: Comparison by the Types of Prior Infection and Vaccine Formulations
Authors: Hyun Hak-Jun , Choi Min-Joo , Nham Eliel , Seong Hye , Yoon Jin-Gu , Noh Ji-Yun , Cheong Hee-Jin , Kim Woo-Joo , Yoon Sun-Kyung , Park Se-Jin , Gwak Won-Seok , Lee June-Woo , Kim Byoung-Guk , Song Joon-Young
Published: August 2023

Bivalent COVID-19 vaccines that contain BA.1 or BA.4/BA.5 have been introduced worldwide in response to pandemic waves of Omicron subvariants. This prospective cohort study was aimed to compare neutralizing antibodies (Nabs) against Omicron subvariants (BA.1, BA.5, BQ.1.1, BN.1, and XBB.1) before and 3–4 weeks after bivalent booster by the types of SARS-CoV-2 variants in prior infections and bivalent vaccine formulations. A total of 21 participants were included. Prior BA.1/BA.2-infected, and BA.5-infected participants showed significantly higher geometric mean titers of Nab compared to SARS-CoV-2-non-infected participants after bivalent booster (BA.1, 8156 vs. 4861 vs. 1636; BA.5, 6515 vs. 4861 vs. 915; BQ.1.1, 697 vs. 628 vs. 115; BN.1, 1402 vs. 1289 vs. 490; XBB.1, 434 vs. 355 vs. 144). When compared by bivalent vaccine formulations, Nab titers against studied subvariants after bivalent booster did not differ between BA.1 and BA.4/BA.5 bivalent vaccine (BA.1, 4886 vs. 5285; BA.5, 3320 vs. 4118; BQ.1.1, 311 vs. 572; BN.1, 1028 vs. 1095; XBB.1, 262 vs. 362). Both BA.1 and BA.4/BA.5 bivalent vaccines are immunogenic and provide enhanced neutralizing activities against Omicron subvariants. However, even after the bivalent booster, neutralizing activities against the later Omicron strains (BQ.1.1, BN.1, and XBB.1) would be insufficient to provide protection.
‘I Flip the Switch’: Aboriginal Entrepreneurs’ Navigation of Entrepreneurial Imperatives
Authors: Manganda Admiral , Jurado Tanya , Mika Jason , Palmer Farah
Published: August 2023

Culture is integral to Indigenous entrepreneurs, but how culture manifests in their entrepreneurial processes is understudied. This paper explores how Aboriginal entrepreneurs in Perth, Australia navigate cultural and commercial imperatives in their entrepreneurial practice. The study uses an interpretive lens and thematic analysis based on Altman’s hybrid economy model (HEM) to explore how ten Aboriginal entrepreneurs managed commercially viable enterprises while meeting their cultural obligations and aspirations. The focus is on the convergence of the customary and market economies and entrepreneurs’ experiences of navigating the hybridity of that space. We find that Aboriginal entrepreneurs iteratively assess the complementarity of cultural and commercial imperatives to protect their Indigenous identity while meeting business objectives. Cultural and commercial imperatives are navigated using context-dependent strategies. Strategies fall within fluid classifications of ‘high cultural–low commercial bias’, ‘high commercial–low cultural bias’, and an even consideration of both. We propose a contingency model to help explain Indigenous entrepreneurs’ approaches to navigating customary and commercial imperatives. This study contributes to knowledge of culture in Indigenous entrepreneurship by uncovering strategies Indigenous entrepreneurs can, and do, use to conduct business in ways culturally attuned to their indigeneity and situations.
Bringing Carnaval Drum and Dance Traditions into 4-H Programming for Latino Youth
Authors: Ginop Evelyn , Braverman Marc , Caruso Robyn , Bone Dennis
Published: August 2023

4-H Bloco Drum and Dance is an afterschool program that teaches adolescents drumming, dancing, and theater arts in the rich traditions of Brazilian Carnaval. Teens learn to express themselves in a variety of modalities and perform at community events. The program was developed by a community coalition that included 4-H, other youth programs, and the school district. Most program participants are Latino, high-risk youth. Program evaluation revealed that 4-H Bloco has positive impacts with regard to cultural appreciation, gang-related attitudes and awareness, health awareness, exercise, and nutrition. Bloco demonstrates the value of culturally relevant arts education in Extension youth programming.
Extension Educators' Perceptions of the Local Food System
Authors: Thomson Joan , Radhakrishna Rama , Bagdonis Jessica
Published: August 2023

Extension educators in three Northeastern states were surveyed about their perspectives on 21 LFS topics. Educators identified all 21 topics to be important. Principal factor analysis was carried out to identify factors that underlie the importance of these issues. Five factors—food access, food system viability, localization of food systems, food safety and land use—accounted for 60.61% of the total variance. Educators' areas of primary program responsibility, gender, and previous participation in LFS activities revealed significant differences across the importance placed on the factors, suggesting that individual perspectives and professional responsibilities influence an educator's commitment to LFS engagement.
Use Automated Phone Calls to Relay Extension Educational Messages
Authors: Fincham Hannah , Bowen Elaine , Davis Kay , Kaczor Cheryl , Lester Dana , Mowbray Rebecca , Porter Brenda
Published: August 2023

West Virginia University (WVU) Extension agents expanded a community-based program for older adults by adding an automated phone call component. Senior participants who attended one or more Taking Charge of Your Health and Safety programs elected to receive follow-up health tips by phone. The automated calls were an efficient, cost-effective, and popular way to relay research-based health information. Automated calls may be useful with a variety of programs across many disciplines.
Is Extension Ready to Adopt Technology for Delivering Programs and Reaching New Audiences?
Authors: Diem Keith , Hino Jeff , Martin Dana , Meisenbach Terry
Published: August 2023

The Cooperative Extension System is at a crossroads regarding educational program delivery and clientele relationships in a digital age. To "help prepare counties for a future that demands increased use of technology for improving work efficiencies and expanding audience outreach," an assessment team was appointed to conduct a case study to investigate the potential for adoption of technology in county Extension programs in the Oregon State University Extension Service. This article contains key findings and recommendations in response to questions the team was charged to answer and assumptions it was asked to explore, many of which have national relevance.
Meeting Extension Programming Needs with Technology: A Case Study of Agritourism Webinars
Authors: Rich Samantha , Komar Stephen , Schilling Brian , Tomas Stacy , Carleo Jenny , Colucci Susan
Published: August 2023

As clientele needs diversify, Extension educators are examining new technologies, including online tools, to deliver educational programming and resources. Using agritourism as the educational topic, the study reported here sought to evaluate participants' acceptance of online educational programming (webinars) and the effectiveness of the technology in meeting the needs of participants and Extension educators. Overall, results provided favorable support of webinars for online educational programming and illustrated the effectiveness of this technology in reaching diverse audiences. Findings suggest webinars can enhance the value, availability, and sustainability of Cooperative Extension programming.
Thinking about the Wave-Particle Duality with Plasma Theory and Explaining it based on the Oscillator and Qseudo-Oscillator Models
Authors: Zhao Shuxia
Published: August 2023

It is the first time for us to observe the quantum world with the plasma theory. Mean-while, many new concepts, such as the discrete quantum, precise quantum and the non-linear quantum, etc., and new horizons, i.e., cutting off the connection of interaction, or equivalently introducing destructive disturbance, are supposed into the quantum mechanics at the first. The normal and pseudo-oscillator models are introduced and used to explain the wave and particle duality of quantum field. By adding such new content, it is hoped that people can understand the physics behind the quantum mechanics, rather than recognizing it with the pure mathematic knowledge. It is suggested that the quantum world is better to consider the influence of outside environment, and then the quantum mechanics is turned into the quantum dynamics. The establishment of quantum dynamics is helpful for people better understand and hence utilize the quantum mechanics, such as the quantum optics, quantum communication and quantum computer, etc.
Histopathological Evaluation Of Liver Changes In Rainbow Trout After Diethlynitrosamine (DEN) Exposure
Authors: YARDIMCI Banu , ONUK Ertan Emek , PEKMEZCİ Gökmen Zafer
Published: August 2023

The aim of this study was to determine the hepatocarcinogenic effect of diethylnitrosamine in rainbow trout (Oncorhynchus mykiss), the most cultivated and consumed fresh water fish. In this study, 120 fish weighing 50-70 g each were used. Randomly selected fish were divided into 3 dosage groups and a control group that contained 30 fish per group. Diethylnitrosaminewas dissolved in 0.1 ml of dimethylsulfoxideat 50 mg/kg, 100 mg/kg and 150 mg/kg, and respectively administered to each of the dosage groups intraperitoneally. On the 15th, 30th and 45th days of the study, 10 fish from each study group were euthanised while under sedation, and necropsies were performed. For histopathological and immunohistochemical examinations, tissues were routinely processed and sections were stained with haematoxylin-eosin and examined by light microscopy. Histology revealed hyperaemia, parenchymal degeneration, mononuclear cell infusion, necrosis, bile ducts hyperplasia, cholangiofibrosis and fatty degeneration of the liver. In immunohistochemical staining, CYP1A was slightly positive in the bile duct epithelium in the C2, A3, B3 and C3 groups, and negative in the other groups. Cytokeratin 18 showed negative staining in all groups. Mild positive staining in the bile duct epithelium, A3, B3 and C3 and negative staining in other groups for glutathione-S-transferase. It was concluded that diethylnitrosamine causes significant damage to liver tissuein fish, even in short-term applications, and may cause neoplastic changes in liver cells over the long term.
Geografías imaginarias: los múltiples espacios de la ciudad en la narrativa de Walter Montenegro
Authors: Velasco Camacho Javier
Published: August 2023

En 1947, Walter Montenegro (1912-1991) publica su segunda colección de cuentos: Los últimos. Montenegro es un autor que narra la ciudad, y lo hace visibilizando dinámicas de desconexión en presencias sin unidad que denomina “últimos”. El carácter de esta construcción es profundamente vanguardista y hace de Los últimos una obra irrepetible: la escritura compone la imagen de la ciudad como una gran geografía de relaciones, lugares y presencias simultáneas que se articulan en la lógica espacial que propone la narración. Así, en los tres cuentos que analizo, este artículo desarrolla los múltiples espacios textuales al interior de la ciudad que describe Walter Montenegro.
El amor romántico en las danzas y canciones de la fiesta del Gran Poder
Authors: Pinto Tapia Bismarck
Published: August 2023

La Entrada del Señor del Gran Poder es una expresión popular del sincretismo andino y occidental. Históricamente evoluciona de ser una fiesta de barrio hacia una compleja organización festiva citadina. La apropiación de la ciudad se hace en niveles transgresores de lo establecido al amparo de la religiosidad. Desde las teorías del concepto de amor de Sternberg, y las actitudes del amor de Lee, se analizan las danzas y canciones para identificar la evolución del concepto de amor en la cultura paceña. Concluye en la presencia del amor romántico como construcción social reivindicativa de lo erótico y lo tierno.
La festividad de Semana Santa en una comunidad chiquitana
Authors: Arrien Gutiérrez Mario
Published: August 2023

A partir de un estudio etnográfico se presenta el desarrollo de la festividad de Semana Santa en una de las comunidades más tradicionales de la Chiquitania. Concretamente se presenta con detalle las ceremonias del Viernes y Sábado Santo, así como del Domingo de Pascua. Este trabajo se centra más en las formas de organización y realización de las festividades que en el campo de los significados chiquitanos de las mismas.
Abril rojo o las formas y consecuencias de la violencia
Authors: Vargas M. Freddy R.
Published: August 2023

El artículo analiza la novela Abril rojo, de Santiago Roncagliolo, publicada en 2006. Este texto, operando a partir de las estrategias de la novela negra, reflexiona en las consecuencias que derivan de la memoria de las acciones de Sendero Luminoso en el Perú de los años 2000. Para ello sigue las acciones de un Fiscal de Distrito de la provincia de Ayacucho que investiga un crimen violento. Sin embargo, esa investigación terminará revelando detalles que van más allá de ese crimen: cómo la memoria de la violencia no desaparece, sino que retorna trastornada; cómo la violencia intoxica a todos, incluso a quienes pretenden neutralizarla; y cómo esa violencia engendra un efecto devastador: la descalificación de lo utópico.
¿Dónde está tu hermano?, pregunta la loba a cada hijo (Una lectura sobre Sara Uribe)
Authors: Velásquez Guzmán Mónica
Published: August 2023

En el presente trabajo, analizo el poemario Antígona González de Sara Uribe, para rastrear cómo se establece allí una poética de lo fraterno en un contexto de desaparición y muerte forzada en el México actual. Esa temática provoca, paralela a la crítica a sistemas políticos, un agudo cuestionamiento al mismo sistema literario por medio de un extremado uso y exposición de intertextos así como de una actitud desafiante ante los modos de circular un libro que se presenta como escrito con y entre otros. Se trata de entender por qué y cómo se reescribe el sitio del familiar de un desaparecido en una poesía cercana al documental, al montaje y a la escucha de protagonistas, testigos y denunciantes.
EĞİTSEL SÜREÇLERİN ÜNİVERSİTE ÖĞRENCİLERİNİN ELEŞTİREL DÜŞÜNME BECERİLERİ ÜZERİNE ETKİSİNİN İNCELENMESİ
Authors: TAŞKIN Buket , SEFEROĞLU S. Sadi
Published: August 2023

İçinde bulunduğumuz çağda, akademik başarıyı desteklediği belirtilen 21.yy becerilerine sahip bireyler yetiştirmek, eğitimin önemli amaçları arasında yer almaktadır. Bu çalışmada BÖTE (Bilgisayar ve Öğretim Teknolojileri Eğitimi) bölümünde öğrenim gören lisans öğrencilerinin sahip oldukları bilgi ve becerilerin, geçirdikleri eğitsel süreçlerin, 21. yy becerilerinden olan eleştirel düşünme becerisi temelinde incelenmesi amaçlanmıştır. Çalışmada karma araştırma yöntemlerinden olan yakınsak paralel desen kullanılarak, nicel ve nitel araştırma tekniklerinden birlikte faydalanılmıştır. Araştırmanın çalışma grubunu, Hacettepe Üniversitesinde BÖTE Bölümü’ne devam eden 67 lisans öğrencisi oluşturmaktadır. Çalışma kapsamında İletişim ve Mesaj Tasarımı dersinde, alanyazından yola çıkarak tasarlanan eleştirel düşünmeyi teşvik edici etkinliklere yer verilmiştir. Öğrencilerin eleştirel düşünmeyi kavramsallaştırma durumlarına ve eleştirel düşünme eğilimlerine ek olarak, tasarlanan ders ve genel müfredat konusundaki değerlendirme verileri de toplanmıştır. Verilerin toplanmasında “Eleştirel Düşünme Eğilimleri Ölçeği” ile bir anket kullanılmıştır. Elde edilen nitel ve nicel verilerin analizi sonucunda öğrencilerin eleştirel düşünmeyi doğru biçimde kavramsallaştırdıkları ve eleştirel düşünme performanslarının sınıf değişkeninden etkilendiği görülmüştür. Eleştirel düşünme eğilim puanlarına bakıldığında 2. sınıfların 4. sınıflardan daha yüksek ortalamaya sahip olmasının önemli bir sonuç olarak dikkat çektiği görülmektedir. Öğrencilerin ders süreciyle ilgili yaptıkları değerlendirmelere bakıldığında, planlanan ders kapsamında bu becerilerin yeterince desteklendiği söylenebilir. Çalışma sonucu ulaşılan bulguların, halihazırda uygulanan eğitim programlarının eleştirel düşünmeyi destekleme anlamında değerlendirilmesi ve geliştirilmesi açısından faydalı olabileceği düşünülmektedir.
Pengembangan Game Edukasi Berhitung (GESIT) untuk Menstimulasi Kemampuan Berhitung Permulaan Anak Usia 5-6 Tahun
Authors: Nanda Novia Dilla Safitri  , Tomas Iriyanto  , Nur Anisa
Published: August 2023

Beginning numeracy skills are the initial basic abilities that learn understanding related to counting objects, simple addition and subtraction. The aim of this research is to produce an educational game product that is appropriate, effective and efficient according to media experts, material experts and practitioners, to stimulate early numeracy skills in children aged 5-6 years. This type of research uses research and development (R&D) and the development model used is ADDIE (analysis, design, development, implementation and evaluation). The media validation test results were 85%, the material validation test results were 90%, then trials on class teachers were 78%, and small group trials obtained 90%, from the four results it can be concluded that the GESIT game is suitable for use by children aged 5-6 years . While the results of the non-parametric statistical test using the Wilcoxon test 0.002 (p-value) with a significance level of 0.05 which means (0.002 (p-value) <0.05) then Ha is accepted and Ho is rejected, namely the influence of the GESIT game on learning outcomes counting the beginning in children aged 5-6 years.
ABSTRAK
Kemampuan berhitung permulaan merupakan kemampuan dasar awal yang mempelajari pemahaman terkait dengan menghitung benda, penjumlahan dan pengurangan sederhana. Tujuan dari penelitian ini adalah untuk menghasilkan sebuah produk game edukasi yang layak, efektif dan efisien menurut ahli media, ahli materi dan praktisi, untuk menstimulasi kemampuan berhitung permulaan pada anak usia 5-6 tahun. Jenis penelitian ini menggunakan research and development (R&D) serta model pengembangan yang digunakan yaitu ADDIE (analysis, design, development, implementasion dan evaluation). Hasil uji validasi media 85%, hasil uji validasi materi 90%, kemudian uji coba terhadap guru kelas 78%, dan uji coba kelompok kecil memperoleh 90%, dari keempat hasil tersebut dapat disimpulkan bahwa game GESIT layak digunakan untuk anak usia 5-6 tahun. Sedangkan dari hasil uji statistik nonparametik menggunakan uji wilcoxon  0,002 (p-value) dengan taraf signifikansi sebesar 0,05 yang artinya (0,002 (p-value) < 0,05) maka Ha diterima dan Ho ditolak yaitu adanya pengaruh game GESIT terhadap hasil belajar berhitung permulaan pada anak usia 5-6 tahun.
Continuing Professionalisme Development (CPD) sebagai Upaya Mengembangkan Kompetensi Guru PAUD
Authors: Kamil Nurhusna , Erni Munastiwi
Published: August 2023

This article is a descriptive qualitative research with multiple objectives. First, to describe and analyze teacher perceptions about the advantages of the CPD program in developing competence. The second objective is to analyze the teacher's thinking after carrying out CPD activities on competency development which has implications for various advantages during learning for students. Empirical data in the form of interviews with the teacher concerned. The study used a purposive sampling sample with the criteria of teachers who have participated in various CPD activities as an effort to develop pedagogic competence. The data analysis technique used starts from identifying problems, reviewing literature, determining research objectives, collecting data, analyzing data, interpreting data and reporting followed by conclusions. The results of the research from the interviews conducted obtained information that the CPD program is very effective and useful in providing opportunities for teachers to develop teacher competencies so as to provide very qualified accessibility of learning services for students in their growth and development period.
ABSTRAK
Artikel ini adalah penelitian kualitatif deskriptif dengan tujuan ganda. Yang pertama, untuk mendeskripsikan dan menganalisis persepsi guru tentang keuntungan program CPD dalam mengembangkan kompetensi. Tujuan kedua, untuk menganalisis pemikiran guru setelah melakukan kegiatan CPD terhadap pengembangan kompetensi yang berimplikasi pada berbagai keuntungan selama pembelajaran terhadap siswa. Data empiris berupa hasil wawancara dengan guru yang bersangkutan. Sampel yang digunakan diambil dengan teknik purposive sampling dengan pengklasifikasian guru yang telah mengikuti berbagai kegiatan CPD sebagai upaya mengembangkan kompetensi pedagogik. Teknik analisis data yang digunakan dimulai dari mengidentifikasi masalah, literature review, menentukan tujuan penelitian, mengumpulkan data, menganalisis data, interpretasi data serta pelaporan yang diikuti dengan kesimpulan. Hasil penelitian dari wawancara yang dilakukan didapat informasi bahwa program CPD sangat efektif dan bermanfaat dalam memberikan kesempatan kepada guru dalam mengembangkan kompetensi guru sehingga memberikan aksesibilitas layanan belajar yang sangat mumpuni bagi peserta didik dalam masa pertumbuhan dan perkembangan mereka.
Cottonwood Cabins: An Investigating into Screw Laminated Mass Timber Construction
Authors:   University of Colorado Denver, Sommerfeld Erik
Published: August 2023

It has been argued that the most significant, yet troubling, legacy of modernism has been the specialization of the various elements of building once directed and harmonized by the master builder.1 Relegating buildings to an individual specialist has inevitably created more complicated building assemblies requiring each material to handle only a particular function. If we are to overcome this oversight, a more complex build¬ing methodology should replace these complicated building systems dominating building construction today.2
Unfamiliar Construction: Material Programming and Deployable Form
Authors:   University of Virginia / After Architecture, Macdonald Katie , Schumann Kyle ,   University of Virginia / After Architecture
Published: August 2023

Consumer-oriented construction is shaped by a collection of plug and play products: dimension lumber, CMUs, appliances, window assemblies, premade vanities, and so forth—an extension of Reyner Banham’s poignant mid-century analysis of the American fascination with gizmos.1 This lingering postwar vision is delivered not as a ready-made kit in the vein of Sears, Roebuck & Co.’s early prefab homes but as individual parts nonetheless intended to go together, furnished by Home Depot, Lowes, Menards, and others.2
Potential of ChatGPT in Biology Teaching and Learning at the Vietnamese High School
Authors: Nguyen Xuan-Hong , Nguyen Hoang-Anh , Cao Linh , hana trương
Published: August 2023

The use of artificial intelligence (AI) technologies in education has gained significant attention in recent years. In this paper, we explore the potential of ChatGPT, a language model based on the GPT-3.5 architecture, in biology teaching and learning at Vietnamese high schools. We discuss the capabilities of ChatGPT in biology as well as potential directions for using this technology in the classroom. We believe that ChatGPT has the potential to be a valuable tool for biology education in Vietnam and can help to improve the quality of education for students. It could be used to provide personalized learning for students, offer feedback on student work, or generate practice questions. ChatGPT could also be used to create interactive learning experiences that engage students and help them to better understand biological concepts.
The Impact of ChatGPT on Vietnamese Education
Authors: Nguyen Thuy , Cao Linh
Published: August 2023

This paper explores the transformative effects of ChatGPT on Vietnamese education. As an advanced language model powered by artificial intelligence, ChatGPT has the potential to revolutionize various aspects of the educational landscape. The paper discusses how ChatGPT is being integrated into the Vietnamese education system, the benefits it brings to students and educators, the challenges it poses, and the prospects for the future of education in Vietnam.
PENGEMBANGAN MULTIMEDIA INTERAKTIF PADA MATERI PERTUMBUHAN DAN PERKEMBANGAN MAKHLUK HIDUP UNTUK KELAS XI SMA
Authors: Ghearika Ghearika
Published: August 2023

Interactive multimedia of living things growth and development was developed with the aim of producing learning media that is interactive multimedia which is valid and practical. Interactive multimedia developed the form of mind maps that are in development using mindjet mindmanager application. This research is a type of Research and Development (R&D) using ADDIE development model, which has included analysis, design, development, implementation, and evaluation. The subject of this research was expert lecturers as subjects who assessed the research tools and tested the validity of interactive multimedia, biology teacher and student of XII MIA 5 at SMAN 14 Gowa as the subject who tested the practicality of interactive multimedia. Research result showed that interactive multimedia is valid and practical. The validity value obtained 96.78% (very valid), while the practicality value obtained from teacher’s response is 96.59% (very practical), and the practicality value obtained from student’s response is 86.33% (very practical). So that, it can be concluded that the interactive multimedia learning media that developed were suitable to use.
Pengembangan E-Modul Biologi Berbasis Contextual Teaching and Learning dengan Mind Mapping pada Materi Sistem Koordinasi Siswa Kelas XI SMA
Authors: Masdi Sri Febriani , Palennari Muhiddin , Syamsiah Syamsiah
Published: August 2023

Penelitian ini merupakan penelitian dan pengembangan yang bertujuan untuk menghasilkan produk berupa emodul biologi berbasis contextual teaching and learnind dengan mind mapping pada materi sistem koordinasi kelas XI SMA. Penelitian ini mengacu pada model pengembangan ADDIE yang terdiri dari lima tahap, yaitu Analisis (Analyze), desain (Design), Pengembangan (Development), Implementasi (implementation), dan Evaluasi (Evaluation). Instrumen penelitian yang digunakan berupa lembar validasi, angket respon guru, angket respon siswa, dan tes hasil belajar. Sampel dalam penelitian ini adalah siswa kelas XI SMA Negeri 2 Luwu. Hasil penelitian menunjukan bahwa: 1) e-modul biologi berbasis contextual teaching and learnind dengan mind mapping memenuhi kriteria valid dengan rerata skor sebesar 4,4; 2) e-modul biologi berbasis contextual teaching and learnind dengan mind mapping memenuhi kriteria praktis berdasarkan hasil respon guru dengan rerata 96.7% pada kategori sangat kuat dan 3.3% pada kategori kuat, sedangkan hasil respon siswa dengan rerata 36.7% pada kategori sangat kuat dan 63.3% pada kategori kuat; 3) e-modul biologi berbasis contextual teaching and learnind dengan mind mapping memenuhi kriteria efektif dengan persentase ketuntasan hasil belajar siswa sebesar 81% (sangat efektif). Berdasarkan hasil penelitian dapat disimpulkan bahwa e-modul biologi berbasis contextual teaching and learnind dengan mind telah memenuhi kriteria valid, praktis dan efektif.
Hubungan Kecerdasan Emosional Dan Motivasi Belajar Dengan Hasil Belajar IPA Peserta Didik Kelas VIII Kepulauan Selayar
Authors: Basri Nelly Suryani , Daud Firdaus
Published: August 2023

This study aims to determine: (1) the description of emotional intelligence, learning motivation, and science learning outcomes for students in class VIII SMPN in Benteng District, (2) The relationship between emotional intelligence and science learning outcomes for students in class VIII SMPN in Benteng Regency. Benteng Regency, (3) the relationship between learning motivation and science learning outcomes for class VIII SMPN students in Benteng Regency, (4) the relationship between emotional intelligence and learning motivation on science learning outcomes for VIII SMPN students in Benteng Regency. This research is an ex post facto research which is correlational. Sampling by means of random sampling. Data were analyzed by descriptive statistics and inferential statistical analysis. The conclusions in this study are as follows. (1) The emotional intelligence of class VIII SMP Negeri in Benteng Subdistrict, Selayar Islands Regency is in the medium qualification. Motivation to learn is in moderate to high qualifications, and student learning outcomes are in low, medium to high qualifications. (2) There is a significant influence of emotional intelligence directly on learning outcomes. (3) There is a significant effect of learning motivation directly on learning outcomes. (4) There is a significant influence between emotional intelligence and learning motivation together on learning outcome.