bluuebunny/crossref_metadata_2025 huggingface dataset:
Прикладні аспекти формування комунікаційної стратегії органу місцевого самоврядування на базі Зимноводівської ТГ
Authors: Шибунька Уляна , Костюк Ольга
Published: December 2021

Анотація. Реалізація комунікаційної стратегії потребує значних фінансових витрат та людського капіталу. Комунікаційна стратегія дасть змогу установі розширити свою діяльність. Мета дослідження: формування комунікаційної стратегії органу місцевого самоврядування на базі Зимноводівської ТГ. Маркетингова комунікація – це підтримання постійного зв’язку з клієнтом, постійне налагодження контакту та формування позитивного іміджу. Комунікаційна стратегія – це план на певний відрізок часу, яким керується компанія при комунікації із різними цільовими аудиторіями. Проблеми більшості територіальних громад у тому, що у них відсутній відділ маркетингу, який повинен бути одним з ключових в установі. Було визначено переваги органу місцевого самоврядування на базі Зимноводівської ТГ з метою залучення потенційних інвесторів та визначено шляхи покращення комунікацій ТГ. Комплексна комунікаційна стратегія має включати як зовнішні комунікації, а саме зв`язки органу місцевого самоврядування із середовищем за рамками установи: різноманітними цільовими групами, засобами масової інформації, представниками інших ТГ, регіональної та національної влади тощо; так і внутрішні комунікації. Завдання нової стратегії повинні включати в себе основні аспекти сфер комунікації. Тому, на основі усіх наявних даних Зимноводівської ТГ було розроблено та проаналізовано основні цілі та завдання стратегії розвитку територіальної громади. Для побудови успішної комунікаційної стратегії потрібен алгоритм. Алгоритм, на основі якого буде побудовано нову комунікаційну стратегію Зимноводівської ТГ. Одним з базових інструментів зовнішньої комунікації рекомендується проведення аналізу Зимноводівської ТГ, результати якого можуть бути цікавими для потенційних інвесторів. Визначено роль так званого «будинку повідомлень» –  шаблону, який має на меті допомогти сформувати структуру комунікацій від основних повідомлень до їх втілення.

Ключові слова: комунікаційна стратегія, маркетингові комунікації, орган місцевого самоврядування, Зимноводівська ТГ.
Використання штучних нейронних мереж в системі ризик-менеджменту підприємства
Authors: Денисов Андрій , Ричкова Лариса
Published: December 2021

Анотація. Статтю присвячено вивченню можливостей та перспектив використання штучних нейронних мереж в системі ризик-менеджменту підприємства. Розглянуті перепони ефективного використання інструментів ризик-менеджменту у діяльності підприємств через об’єктивні та субєктівні чинники. В рамках дослідження ризик розглядається як можлива небажана подія, яка переводить об’єкт управління у небажаний стан. Спираючись на базові поняття та характеристики функціонування штучних нейронних мереж і постулати економічної теорії автор робить висновки щодо можливостей, переваг та проблем різних аспектів застовування моделей штучних нейронних мереж при прийнятті управлінських рішень щодо оцінки ризиків та зменшення їх негативних наслідків. У статті розглянуто особливості ризикових ситуацій при прийнятті управлінських рішень в інтенціональній, експектаційній, когнітивній та функціональній підсистемах управління ризиками. Виділено принципи, дотримання яких необхідне для коректного використання штучних нейронних мереж у підготовці управлінських рішень та накопиченні інформації про рівень потенційного ризику. Доведено, що використання моделей штучних нейронних мереж дозволять перейти від традиційного реактивного менеджменту у відповідь на ризикові події до проактивного, який передбачає управлінські впливи на причини виникнення ризиків і опосередковано на негативні події та їх наслідки.  З’ясовано, що у разі занадто високої швидкості зовнішніх змін і низькому темпі пристосування до них, можуть наступити несприятливі наслідки для підприємства у вигляді дестабілізації його діяльності. Висновком з цього є те, що використання штучної нейронної мережі в системі управління рівнем ризику сприятиме подоланню фрагментарності даних, які є у розпорядженні підприємства, що, в свою чергу, буде підвищувати швидкість процесів прийняття управлінських рішень. Використання штучних нейронних мереж надає підприємствам певні переваги з точки зору управління економічними ризиками через підвищення точності та зниження  суб’єктивності управлінських рішень, більш детальне вивчення процесів та ситуацій з використанням різноманітних методів аналізу та великої кількісті алгоритмів.

Ключові слова: штучні нейронні мережі, підприємство, управлінські рішення, ризик.
Бенчмаркінг як сучасний інструмент розвитку потенціалу підприємства
Authors: Шкуренко Ольга
Published: December 2021

Анотація. Забезпечення ефективності функціонування і зміцнення потенціалу підприємства, конкурентоспроможності на ринку можливо досягти за рахунок використання сучасних управлінських технологій, однією із яких є інструментарій бенчмаркінгу, що дозволяє мати чітке бачення кінцевої мети своєї діяльності, як для самого підприємства, так і для партнера.

Бенчмаркінг являє собою постійний процес порівняння продуктів (товарів), виробничих процесів, методів, форм та систем управління, інших характеристик підприємства в цілому та його окремих частин (підсистем) з подібними елементами виробничо-управлінського типу інших організацій. В умовах сьогодення бенчмаркінг застосовується в управлінні розвитком соціально-економічних систем різних рівнів, а також як методологія оцінювання поточного стану для визначення перспектив реалізації заходів. Також на основі бенчмаркінгового підходу здійснюється стратегічне планування показників діяльності підприємства, що впливає на розвиток потенціалу.

Доведено, що бенчмаркінг є важливим інструментом реалізації взаємовідносин з конкурентами, застосування якого призводить до розвитку потенціалу підприємств та зміни конкурентоспроможності. Акцентовано увагу на тому, що бенчмаркінг сприяє відкритості й підвищенню ефективності бізнесу, а саме надає підприємству сигнали раннього попередження щодо відставання; з’ясовує рівень підприємства у порівнянні з кращими в світі; приводить до швидкого впровадження нових підходів за мінімального ризику; скорочує витрати на про процес поліпшення.

В статті розглянуто бенчмаркінг потенціалу, під яким розуміється вивчення передового досвіду управління ресурсами підприємства, а також ринкової позиції конкурентів з точки зору використання цих ресурсів потенціалу для цілей підвищення своєї конкурентоспроможності, автентичності, ділового іміджу та привабливості.

Автором в статті побудовано алгоритм розроблення стратегії розвитку потенціалу на засадах бенчмаркінгу, який описує послідовність і зміст основних етапів використання бенчмаркінгу на підприємстві. Побудовано бенчмаркінгову «павутину» конкурентоспроможності продукту для визначення напрямів підвищення конкурентоспроможності.

Ключові слова: бенчмаркінг; розвиток потенціалу; інструмент; павутина конкурентоспроможності; конкуренти; ефективність.
Determinants of some pentadiagonal matrices
Authors:   Faculty of Economics, University of Debrecen, 4032 Debrecen, Böszörményi u.138, Hungary, Losonczi László
Published: December 2021

In this paper we consider pentadiagonal \((n+1)\times(n+1)\) matrices with two subdiagonals and two superdiagonals at distances \(k\) and \(2k\) from the main diagonal where \(1\le k \lt 2k\le n\). We give an explicit formula for their determinants and also consider the Toeplitz and “imperfect” Toeplitz versions of such matrices. Imperfectness means that the first and last \(k\) elements of the main diagonal differ from the elements in the middle. Using the rearrangement due to Egerváry and Szász we also show how these determinants can be factorized.
Approximation of nilpotent orbits for simple Lie groups
Authors:   Institut Elie Cartan de Lorraine, CNRS - UMR 7502, Université de Lorraine, France, Fresse Lucas , Mehdi Salah ,   Institut Elie Cartan de Lorraine, CNRS - UMR 7502, Université de Lorraine, France
Published: December 2021

We propose a systematic and topological study of limits \(\lim_{\nu\to 0^+}G_\mathbb{R}\cdot(\nu x)\) of continuous families of adjoint orbits for a non-compact simple real Lie group \(G_\mathbb{R}\). This limit is always a finite union of nilpotent orbits. We describe explicitly these nilpotent orbits in terms of Richardson orbits in the case of hyperbolic semisimple elements. We also show that one can approximate minimal nilpotent orbits or even nilpotent orbits by elliptic semisimple orbits. The special cases of \(\mathrm{SL}_n(\mathbb{R})\) and \(\mathrm{SU}(p,q)\) are computed in detail.
Strengthening the Character Values in the Online Learning Process
Authors: Hidayat Wahyu , Dewi Putri , Nurdiana Yana
Published: December 2021

The application of character values ​​in the online learning process for Islamic Religious Education (PAI) subjects is a must even though it is not done face-to-face. The purpose of this study is to photograph the character values ​​taught and the challenges PAI teachers face in implementing character education in the online learning process. This type of research uses qualitative research. The sources of data in this study are teachers and students. Data were collected through interviews, documentation, and direct observation of online learning via Google Meet and WhatsApp group. The data analysis technique used is descriptive qualitative. The dominant character values ​​in online learning of Islamic religious education at SDN 114 Leppangang Pinrang are independence, love of reading, discipline, and responsibility. Some methods of implementing character education include giving advice, giving punishments and rewards in adding and subtracting task scores, and controlling student conversation in the WhatsApp group. PAI teachers have their challenges in applying student character values, one of which is not optimal control, parental concern for controlling their children, and technical problems.
Penerapan Konseling Kelompok Rational Emotive Behavior dan Psikoedukasi di Sekolah Islam; Dampaknya terhadap Penalaran Moral Siswa
Authors: Purwati Purwati , Japar Muhammad , Qomariyah Laili
Published: December 2021

Along with the development of the times and culture's contact from outside, the moral boundaries that are firmly held by the community are increasingly unclear. At school, for example, many students experience a decline in moral reasoning. However, the limited literature that focuses on improving moral reasoning with a quasi-experimental approach, the author will examine psychological interventions Rational Emotive Behavior Counseling (REB) and Psychoeducation (PSE). This study aims to identify differences in effectiveness between group counseling interventions with PSE and REB in improving students' moral reasoning. The author uses a quasi-experiment with a pretest-posttest follow-up design. The study subjects were Sarbini Islamic Junior High School students who had low moral levels. The research subjects consisted of 22 students divided into 11 students in the PSE group and 11 students in the counseling group with the REB approach. The data analysis results showed differences in students' moral reasoning in the REB and PSE groups. The average increase in students' moral reasoning was higher in the REB group than in the PSE group. The author concludes that group counseling with REB and PSE approaches can be applied to improve moral reasoning in students in schools, especially those based on Islam. However, for more optimal results, the authors suggest using REB.
Possível transmissão de mãe para filho da covid-19 através da amamentação
Authors: Santos Valdislaynner Khimberly do Nascimento , Oliveira Danielle Cássia de , Peixoto Alisse Maria Chaves de Lima , Ferraz Lívia Almeida Amaral
Published: December 2021

Com a propagação alta e rápida da covid-19 na população, algumas preocupações foram levantadas, como a segurança de mulheres grávidas e que estão no período de amamentação. Essa atenção é sobre a possível transmissão de mãe para filho através do leite materno. Objetivo: verificar a possibilidade de uma possível transmissão de mãe para filho através do leite materno. Métodos: A buscas de artigos foi realizada nas bases de dados eletrônicos Scielo, Pubmed e Lilacs. Para a busca de artigos foram utilizadas palavras-chave “amamentação”, “leite materno” e “covid-19”, a busca na literatura se deu nos últimos 3 anos. Resultados: Ao realizar a triagem utilizando os critérios de inclusão, tem-se para estudo um total de 8 artigos, onde 50% destes artigos apresentaram amostras negativas do SARS-CoV-2 nos leites maternos, enquanto os outros 50% identificaram o SARS-CoV-2 presentes em ao menos 1 amostra de leite materno. Conclusão: Os estudos abordados nesta revisão revelaram que o aleitamento materno não é considerado um meio de transmissão vertical para o coronavírus.
Terapia de substituição renal em pacientes acometidos pela Covid-19 em uma Unidade de Terapia Intensiva no interior de Rondônia
Authors: Sottocornola Sara Ferreira , Silva Rittiela Rocha da , Barbosa Shirley Junqueira , Queiroz Amanda Gabrielle Silva , Souza Rafael Zondonadi de , Bulgarelli Érico Minoru Narahashi
Published: December 2021

A pesquisa foi realizada a partir da análise de prontuários de pacientes que adquiriram Lesão Renal Aguda (LRA) e necessitaram da Terapia de Substituição Renal (TSR) nas internações em Unidades de Terapia Intensiva Covid do Hospital Regional de Cacoal (HRC) no Interior de Rondônia. É um estudo descritivo, transversal, retrospectivo e de abordagem quantitativa. Após aplicar os critérios de exclusão, ficaram aptos para a análise 188 prontuários no período de junho de 2020 a junho de 2021. Dos 188 pacientes, 108 pessoas eram do sexo masculino (57%), com média de idade de 62,44, mínima de 23 e máxima de 94 anos. Diabetes, hipertensão e obesidade foram as doenças pré-existentes mais prevalentes no estudo com 84%, e 6% dos pacientes desenvolveram LRA sem ter nenhuma comorbidade declarada. Observa-se nesse estudo um índice elevado de pacientes que evoluíram para a hemodiálise com um desfecho alto de mortalidade com os exames laboratoriais alterados, totalizando 93% dos óbitos e 7% de altas. A LRA em pacientes internados com a Covid-19 está entrelaçada a um mau prognóstico com um grande índice de mortalidade, que o estado hiper inflamatório afeta as células renais, ocasionando a necessidade da terapia de substituição renal.
Covid-19: uma análise das notificações de casos positivos no Estado do Paraná em 2020, com ênfase na doença renal crônica
Authors: Silva Carine Priscila da , Benvegnú Dalila Moter , Zanelatto Carla , Nishiyama Márcia Fernandes
Published: December 2021

A Covid-19 é uma doença infectocontagiosa causada pelo coronavírus SARS-CoV-2 que resultou em uma pandemia global. Seu principal mecanismo de entrada nas células é por meio da enzima conversora de angiotensina 2 (ECA-2) e fazem parte do grupo de risco os idosos e portadores de doenças crônicas não transmissíveis (DCNT), dentre elas, a doença renal crônica (DRC).  O objetivo foi caracterizar a amostra de indivíduos notificados com Covid-19 e DRC, segundo características clínicas e demográficas. Estudo de caráter quantitativo, transversal, com dados retrospectivos, obtidos por meio de banco de dados secundário, do sistema e-SUS NOTIFICA, no período de março de 2020 até 8 de dezembro de 2020. Para o período analisado, o total das notificações era de 992.911 indivíduos, sendo 110.908 testados positivos. Fez-se análise descritiva e foram incluídos somente os pacientes com diagnóstico confirmado de Covid-19. Sendo assim, concluiu-se que, dentre o total de analisados positivos, a maioria era do sexo masculino (46,2%), com idade média de 41,42 anos e desses, 445 possuíam DRC. Ainda, dos 110.908 casos, 52,4% apresentaram algum tipo de sintoma característico da Covid-19. O teste mais utilizado para diagnóstico foi o Teste Rápido – Anticorpo (93,3%). Para pacientes com DRC e Covid-19, houve predominância do sexo feminino (53,0%), a idade média foi de 53,71 anos, a maioria sintomática (59,3%) tendo o diagnóstico confirmado pelo Teste Rápido – Anticorpo (86,5%).
Perfil dos praticantes de beach tennis no município de Criciúma
Authors: Rosa Thainá Ribeiro da , Alvarez Bárbara Regina
Published: December 2021

O Beach Tennis atualmente é uma prática que vem crescendo muito no mundo inteiro, especialmente pela facilidade com que uma pessoa aprende a jogar e pela diversão que ele proporciona. O Beach Tennis é um esporte praticado em quadra de areia, com regras e execução de movimentos semelhantes às do tênis. Com a recém chegada do esporte nas quadras de Criciúma, este estudo tem como objetivo analisar o perfil dos praticantes de beach tennis no município, tratando-se de uma pesquisa de abordagem quantitativa descritiva para análise dos dados que foram coletados através de um questionário com perguntas fechadas que foi elaborado com o objetivo de identificar o perfil dos praticantes. Participaram da pesquisa 81 praticantes voluntários. Concluiu-se que o público que pratica o esporte na cidade de Criciúma é composto por sua maioria no gênero feminino 75,3%, idades entre 25 a 35 anos. Em nível de escolaridade 85,2% possuem ensino superior e 60,5% são casados. Os praticantes por sua maioria são funcionários em empresa privada, empresários e profissionais liberais onde possuem uma renda mensal acima de 3.500 reais (80,20%) e moram em Criciúma (87,70%), em uma distância entre 1 a 4 km e todos utilizam automóvel como meio de transporte. Quanto as características dos treinos a maioria treinam de 1 a 3 meses (48,15%), praticam por recreação (59,26%), pelo fato da maioria ser iniciante no beach tennis eles participam da categoria D (44,83%) nos campeonatos e também 75,30% possuem raquete própria e não treinam somente o beach tennis.
O uso da própolis como coadjuvante ao tratamento periodontal
Authors: Braz Aurea Joanna Silva , Fagundes Dyana dos Santos , Espíndola Laís Christina Pontes
Published: December 2021

A doença periodontal (DP) é definida como uma infecção de natureza polimicrobiana multifatorial, que resulta em um processo inflamatório crônico o qual afeta os tecidos de proteção e sustentação dos dentes, que pode resultar na perda do elemento dentário. A introdução do uso de antimicrobianos como adjuvantes a terapia mecânica torna-se uma opção terapêutica para melhorar a higiene oral. Produtos naturais têm sido utilizados cada vez mais para o controle químico do biofilme dentário. Dentre eles, destaca-se a própolis, que é um componente resinoso coletado pelas abelhas em diferentes partes das plantas, que apresenta atividade como um agente preventivo de cáries e no tratamento das doenças periodontais, em razão de sua ação bactericida, fúngica e anti-inflamatória. O objetivo desse estudo é verificar o efeito do uso da própolis no tratamento das doenças periodontais, abordando meios de utilização, vantagens e desvantagens da própolis na periodontia, através de uma revisão de literatura. Foram realizadas buscas nas bases de dados Scientific Eletronic Library Online (SciELO), Biblioteca Virtual em Saúde (BVS), US National libraryof Medicine National Institutes of Health (PubMed), Google Acadêmico, bem como artigos em bases de dados de instituições de ensino superior no Brasil. De acordo com os dados disponíveis na literatura, pode-se concluir que o uso da própolis como coadjuvantes ao tratamento mecânico periodontal em pacientes com doenças periodontais apresenta efeitos significativos positivos nos parâmetros clínicos periodontais e microbiológicos, visto que a própolis apresenta atividade anti-inflamatória e antimicrobiana.
Evaluation of the economic viability of grid-connected photovoltaic systems in different Brazilian regions
Authors: Ozanski Adrielle Cristina , Cruz Maurício Ivan , Siqueira Jair Antonio Cruz , Gazola Thaís Caroline , Silva Renata Galvan Rutz da , Tokura Luciene Kazue , Nogueira Carlos Eduardo Camargo
Published: December 2021

This study aimed at the dimensioning and economic analysis of grid-connected photovoltaic systems in different cities in Brazil. As a criterion for the selection of the cities of interest, it was considered the capital with the highest number of residences in each of the five regions of the country, as well as the city where the authors are established, namely the cities of Salvador, Manaus, Goiânia, São Paulo, Curitiba, and Cascavel. Based on local characteristics and adopting an average monthly electricity consumption of 400 kWh, was developed the dimensioning of the photovoltaic systems, adopting the methodology presented by Pinho and Galdino (2014). Based on the components determined for the systems, budgets were made to enable their implementation. The investments to be made varied between US$ 4,682.97 and US$ 5,326.06. From these values, economic analyses were made using the discounted payback method. The projects presented different payback times, with the shortest payback time to the city of Manaus, with 9 years and the longest in the city of Curitiba, with 15 years. Therefore, it was confirmed the research hypothesis that the regional characteristics linked to the dimensioning of the photovoltaic systems directly affect the time of return on investment.
Intervenções aplicadas a prescrição, uso e administração de medicamentos como fatores estratégicos para a segurança do paciente: revisão sistemática
Authors: Oliveira Thais Castro de , Vieira Haila Kelli dos Santos , Elmescany Sâmella Benoliel , Gonçalves Silvia Tavares , Santos Valéria Regina Cavalcante dos , Soler Orenzio
Published: December 2021

Objetivo: Identificar intervenções aplicadas a prescrição, uso e administração de medicamentos como fator estratégico para a segurança do paciente. Método: Revisão sistemática. Resultados: Foram recuperados 20 estudos feitos nos cinco continentes, englobando países de baixa, média e alta renda. Quanto aos desenhos de estudo utilizados, tem-se 1 estudo clínico controlado randomizado, 2 estudos de coorte, 10 estudos transversais, 1 estudo econômico, 5 revisões sistemáticas e 1 relato de experiência. Apresenta-se as categorias de intervenções quanto aos aspectos estruturais e tecnológicos, organizacionais e profissionais, regulatórios, educacionais, impacto financeiro e interdisciplinares e multifacetadas. Conclusão: Reconhece-se a existência de distintas intervenções que promovem práticas seguras do uso de medicamentos no ambiente hospitalar.
Influência das comorbidades na saúde dos idosos frente à pandemia da Covid-19: uma revisão integrativa
Authors: Sousa Alécio Henrique da Silva , Martins Stanley Bastos , Cortez Antonio Carlos Leal
Published: December 2021

Objetivo: elucidar, através de uma revisão integrativa, evidências científicas acerca da influência das comorbidades na saúde dos idosos frente à pandemia da COVID-19. Métodos: trata-se de um estudo de revisão integrativa da literatura, realizada na base de dados BVS através dos descritores controlados idoso, comorbidade e COVID-19, bem como suas traduções para o espanhol e inglês, de acordo com os DeCS e Mesh, publicados entre os anos de 2020 a maio de 2021. Resultados: Identificaram-se um total de 12 comorbidades associadas à infecção por COVID-19 em idosos nos estudos selecionados nessa revisão. Sendo a principal constituída pelas doenças cardiovasculares, que corresponderam a 72,72%, seguida pela diabetes (72,72%), hipertensão (63,63%), doença renal crônica e obesidade com 27,27%, demência e doença pulmonar obstrutiva crônica com 22,72%, câncer (18,18%), doença hepática (9,09%), asma, dislipidemias e depressão com 4,54%. Considerações Finais: Pode-se concluir que as principais comorbidades observadas na saúde dos idosos frente à pandemia da COVID-19 estão associadas a um aumento significativo do risco de hospitalização e alto índice de mortalidade nessa população. O real motivo que leva as infecções pelo SARS-CoV-2 serem mais graves e fatais no idoso ainda não é bem elucidado, as hipóteses viáveis são emergentes e abrangem mais do que as comorbidades, incluindo repertório imunológico, atividade de inflamassomas, influências genéticas e epigenéticas.
Xerophorus donadinii (Bon) Vizzini, Consiglio & M. Marchetti (Callistosporiaceae: Agaricales) from Mediterranean Region of Turkey
Authors: KAYGUSUZ Oğuzhan , ŞENGÜL Meryem Şenay
Published: December 2021

Xerophorus donadinii (Bon) Vizzini, Consiglio & M. Marchetti has been identified from the Mediterranean Region of Turkey based on morphological characters and molecular phylogenetic studies. A combined dataset generated from nuclear ribosomal internal transcribed spacer and nuclear ribosomal DNA large subunit gene sequences is used to assess its position within Callistosporiaceae. Color photographs from its natural habitat, morphological descriptions and line-drawings of microscopic characters are provided.
Application of the constitutional-typological approach in the study of the morphometric features of the dentition in people with the brachypalatinal type of the palatine arch
Authors: Davydov B. N. , Kochkonyan T. S. , Domenyuk D. A. , Dmitrienko S. V. , Ivancheva E. N. , Lapina N. V.
Published: December 2021

The fundamental problem of precision medicine is the division of the population of sick and healthy people into separate individuals, differing in the likelihood of disease occurrence and the ability to respond to various types of therapy. This is mainly due to the individual, constitutional features of the structure, including the dentoalveolar system. The introduction of a constitutional-typological approach in a comprehensive study of the human dentition is an important task of modern dentistry, since it allows one to determine the characteristic morphological and functional characteristics of each individual individual to improve the methods of diagnosis and treatment of dentoalveolar pathology. The article examines the morphometric features of the dentoalveolar system in people with brachypalatinal («wide» and «low») type of palatine vault, as well as their relationship with the shape of dental arches and the size of the inter-incisal angle at a physiological occlusal norm. As a result of the study, the following regularity was determined: the brachypalatinal type of the palatine vault corresponds to «wide» dental arches of the brachygnathic type with an inter-incisal angle of more than 145 degrees. The value of the brachypalatinal index of the palatine fornix, as the ratio of the height of the palate to its width, exceeds 45 percent, and the gnathic index of the dental arches is 0.59 ± 0.03. The data obtained can be used in the clinic of orthodontics, orthopedic dentistry, maxillofacial surgery to assess the parameters of the hard palate, diagnose pathological forms of the palatine fornix and determine the effectiveness of the treatment.
The use of the rinse aid based on a complex of natural citrus bioflavonoids for gingivitis. Clinical study
Authors: Baykulova S. B. , Turkina A. Y.
Published: December 2021

According to the Federal State Program of Primary Prevention of dental Diseases among the population of Russia in 2011 in the age group of 35–44 years, conducted by STAR, the prevalence of periodontal diseases is high – more than 80%. The high prevalence is due to the low level of oral hygiene. In addition to the standard protocol for the treatment of periodontal diseases, dentists prescribe antibacterial mouthwashes for home use. The combination of chlorhexidine 0.05% + CITROX can act as an alternative to pure chlorhexidine. This combination contributes to less plaque formation, reduces bleeding gums and has an anti-inflammatory effect. It was also noted that this rinse aid has a more pleasant taste and less pronounced side effects.
Clinical and diagnostic value of the method of chromato-mass spectrometry of microbial markers in case of damage to the oral mucosa in children by rheumatic diseases
Authors: Skakodub A. A. , Admakin O. I. , Mamedov Ad. A. , Geppe N. A. , Simonova A. V.
Published: December 2021

Due to the presence of a large percentage of 42.6% secondary oral infection in children with rheumatic diseases [1, 2], which arose during long-term treatment of shock and maintenance doses of anti-inflammatory therapy, it was important to study the microbiota [16, 17]. This paper for the first time applied a modern method for assessing the microbiota of various biotopes of the affected oral mucosa in children with rheumatic diseases – chromatosis-mass-spectrometry (CMSM), based on the quantitative determination of the level of markers of microorganisms: fatty acids, aldehydes, alcohols [5, 7, 10, 11]. СMSM is a highly sensitive method with a wide diagnostic spectrum. The study of a wide range of microorganisms provides new opportunities in the diagnosis of oral dysbacteriosis and increasing the effectiveness of individual treatment. The aim of the study is to improve the level of diagnosis and treatment of oral mucosal diseases in children with rheumatic diseases, through the use of chromato-mass-spectrometry of the oral microbiota.
Pulp hyperemia: analysis of treatment based on the results of a survey of dentists
Authors: Postnikov M. A. , Gaylis K. P. , Sadykov M. I. , Chigarina S. Y. , Shukhorova Y. A. , Khaykin M. B. , Sagirov M. R.
Published: December 2021

The purpose of the study: to analyze the methods of treatment of deep caries by dentists of the Samara region.

Materials and methods. In 2021, 220 specialists of the Samara region were surveyed on the treatment of deep dental caries on the bases of budgetary and extra-budgetary organizations. The questionnaires contained 20 questions that provided information about the level of professional training of specialists, the degree of their awareness of quality criteria and standards, the use of modern technologies and the implementation of each stage of deep caries treatment. The statistical significance of the obtained results (p) was calculated using the Student’s criterion (t) and its interpretation based on the standard table of critical values of the Student’s coefficient. Spearman’s rank correlation method was used to determine the strength and direction of the correlation.

Results. The majority of dentists – 89.9% use a medical pad in the treatment of deep caries, of which 38.7% of respondents use this pad only when accidentally opening the tooth cavity. Based on the answers to the questionnaire, 77.0% of respondents prefer calcium-containing self-hardening medical pads and only 4.6% use MTA-based pads. A comparative analysis of doctors with rare early complications and doctors with frequent early complications showed that doctors of the second group apply a medical pad when opening the tooth cavity 25% more often than doctors of the first group when performing necrectomy in full volume in both groups. A comparative analysis of doctors with rare late complications and frequent late complications did not reveal a statistical significance between the imposition of a medical pad and the opening of the tooth cavity during a complete necrectomy in doctors of the first and second groups. Complications after the treatment of deep caries may be due to an incorrect interpretation of reversible and irreversible changes in the pulp, and in this regard – incorrectly chosen treatment tactics.

Conclusion.The success of the treatment of deep carisea largely depends on the correct determination of reversible and irreversible changes in the pulp of the tooth.
Results determination of need patients to implantology dentistry help in depending of extent’s occlusion defects in different territorial-administrative zone of Tajikistan
Authors: Аshurov G. G. , Ismoilov A. A.
Published: December 2021

Aim. To define the needs of patient in implantology dentistry help in depending of extent defect teeth rows beside populations living in different region of the Republic of Tajikistan.

Material and methods. In the article are presents the results determination of needs patients to implantology dentistry help in depending of extent defect teeth rows beside populations living in different region of the Republic of Tajikistan. In examined group entered dentistry patients both sexual difference with defect of the teeth rows which were divided into 3 groups: 1st group formed the 372 patients with small defect of the teeth rows (absence 1–3 teeth); in 2nd group entered 783 examined patients with average extent (absence 4–6 teeth) of the defect of teeth row; 3rd group formed 109 patients with greater defect of the teeth rows (absence more than 6 teeth). For the reason studies of extent defect teeth rows organized clinical and epidemiological examination of the orthopedic status in different territorial-administrative zone.

Results. Amongst examined persons in respect of defect of the teeth rows by small extent exists reliable reduction their prevalence on measure of the increase the age, then comparatively occlusion defects with average and big extent noted reliable increase of the factor of prevalence.

Conclusions. Got material allow to improve rendering of implant’s prosthesis in depending of extent occlusion defects and hereinafter completely shorten the risk of invalidation chewing device.
The Influence of Leadership Style and Organizational Culture on Job Satisfaction of the CUG Konsepsi Filosofi Petani Pancur Kasih Pontianak
Authors: Arestia Nova
Published: December 2021

The purpose of this study is to determine the influence of leadership study variables and organizational culture both simultaneously and partially on the job satisfaction of Credit Union Gerakan Konsepsi Filosofi Petani Pancur Kasih Pontianak Activists. The analytical method used is referred to as the associative method and multiple linear regression analysis. The respondents of this study are all Credit Union Gerakan Konsepsi Filosofi Petani Pancur Kasih Pontianak Activists totalling 33 people. The results of applying this study to an F test show that there is a simultaneous influence between leadership style variables and organizational culture variables on job satisfaction while the results of hypothesis testing using a T-test show that there is a partial influence between leadership style variables on job satisfaction, but there is no partial influence between organizational culture variables on job satisfaction. The conclusion from the results of this study is that the leadership style variables and organizational culture variables have a simultaneous influence on job satisfaction, and there is a partial influence of leadership style variables on job satisfaction but there is no influence of organizational culture variables on job satisfaction.
Aplicación de la ley del impuesto al valor agregado en las operaciones de comercio electrónico
Authors: Durán-Sánchez Yosmary-Carolina , Briceño- Núñez Chess-Emmanuel , Montilla-Soto Alen-David
Published: December 2021

El internet se ha convertido en un medio para la tributación en la ejecución de compra-ventas en línea. Esta investigación analiza la aplicabilidad de la Ley del Impuesto al Valor Agregado en las operaciones del comercio electrónico en Venezuela, como apoyo a las empresas legamente establecidas que ejecutan este tipo de comercio. Se presenta una investigación documental y descriptiva de campo, con una entrevista semi-estructurada, cuya población está compuesta por tres integrantes del departamento de fiscalización del Servicio Nacional Integrado de Administración Aduanera y Tributaria, para la cual se realizó un análisis de contenido, plasmada en una matriz de triangulación. Se concluyó que la Ley del Impuesto al Valor Agregado es aplicable a las empresas que realizan operaciones de comercio electrónico, siempre que las actividades que ejecutan quedan gravadas según lo que establece la Ley.
Estudio sobre la percepción de los empleados y su influencia sobre el clima de aceptación de la diversidad y la orientación sexual de los empleados
Authors: Santiago-Ortega Rosaliz , Medina-Rivera Zulma , Castro-Gonzáles Segundo
Published: December 2021

Esta investigación tuvo como propósito analizar la percepción que tienen los empleados sobre distintas variables (tales como género, generación, religión y nacionalidad) sobre el Clima de aceptación de la diversidad (CAID), y este con respecto a la Percepción sobre orientación sexual (POS). La información se recopiló mediante un cuestionario validado suministrado a 509 trabajadores pertenecientes a diferentes áreas de negocios, y se analizaron los resultados con los modelos Structural Equation Models-Partial Least Square. Este estudio encontró que el CAID tiene una relevancia importante y positiva sobre la POS de los trabajadores, y que la percepción del género del empleado está influenciada fuertemente por la generación del trabajador. Otros modelos que han intentado medir el CAID no han incluido la variable POS, a diferencia de esta investigación, la cual aporta a la disciplina de Recursos Humanos.
CHEMICAL CONTROL OF HELMINTHOSPORIUM LEAF SPOT OF PERENNIAL RYEGRASS
Authors: Kostenko Sergey , Kostenko Natalia , Razgulyaeva Natal'ya , Puca Nikolay
Published: December 2021

The results of experiments to determine the effectiveness of the Bravo fungicide in the fight against Helminthosporium leaf spot are presented. It was found that early spring spraying of perennial ryegrass with Bravo at a dose of 1.5 l/ ha reduced the development of the disease by 5 times compared to the control.
FEED PRODUCTION IN AGRICULTURAL ENTERPRISES OF THE KIROV REGION
Authors: Sitnikov Nikolay
Published: December 2021

The state of the agro-industrial complex of the Kirov region, the factors hindering its development, key problems are analyzed, the main directions of intensification of the industry are proposed on the basis of the implementation of the achievements of modern agricultural science and practice, the use of innovative technologies in fodder production.
DEVELOPMENT OF LIVESTOCK BASED ON MODERN FEED PRODUCTION
Authors: Sitnikov Nikolay
Published: December 2021

The state of animal husbandry in the country, directions of intensification of the industry, factors that restrain the growth of economic efficiency of animal husbandry, the influence of feed production on the development of animal husbandry are analyzed. The directions of increasing the economic efficiency of forage production by increasing the proportion of proteins in the feed used, improving their structure by expanding the crops of perennial legumes and legume-cereal grass mixtures are proposed.
EVALUATION OF THE INITIAL MATERIAL OF THE FESTULOLIUM FOR THE STEPPE CONDITIONS OF THE CENTRAL CHERNOZEM REGION
Authors: Ivanov Iosif , Zolotarev Vladimir , Chekmareva Anna
Published: December 2021

In recent decades, a new feed crop, festulolium, has been widely used in the feed production of Russia. In this regard, an important task is the permanent creation of a line of festulolium varieties that ensure high efficiency of using this crop in various climatic and ecological conditions. The article presents the material on the assessment of the initial material of the festulolium in the steppe conditions of the Central Chernozem region.
DYNAMICS OF EASTERN GOAT'S SEED YIELD DEPENDING ON THE SOWING PERIOD
Authors: Zolotarev Vladimir
Published: December 2021

Eastern goat's rue (Galega orientalis Lam.) is one of the most priority crops among non-traditional species and its cultivation areas in different regions of the country tend to grow steadily. Due to the southern origin of eastern goat's rue in the conditions of the Non-Chernozem zone, it develops slowly in the first year of life, which requires studying its adaptive properties and developing agricultural techniques for new cultivation areas. An important agricultural method that determines the intensity of the development of eastern goat's rue plants in the year of sowing and the amount of seed yield in the next two years is the sowing period. It is optimal to sow in the early spring at the onset of physical ripeness of the soil, the permissible period is until the end of May.
IMPORT SUBSTITUTION OF SEEDS OF AGRICULTURAL CROPS ON THE EXAMPLE OF THE KALININGRAD REGION
Authors: Buyankin Nikolay
Published: December 2021

In the 90s of the last century, the existing seed production system was headed by the Kaliningrad Agricultural Experimental Station (now the Kaliningrad Research Institute of Agriculture) and about 50 specialized seed farms. In the course of the agrarian reform being carried out at that time and as the state and collective farms were reorganized into LLPs, JSCs, etc. the destruction of the existing seed production system took place. The author conducts a systematic analysis of the current situation and proposes import substitution of fodder seeds using the example of the Kaliningrad region.
Antifungal Polymeric Materials and Nanocomposites
Authors: Ntow-Boahene Winnie , Cook David , Good Liam
Published: December 2021

Rising global populations due to medicinal advancements increases the patient population susceptible to superficial and severe fungal infections. Fungi often implicated in these diseases includes the dermatophytes (Microsporum spp., Epidermophtyon spp., Trichophyton spp.) as well as species of the Candida spp., Aspergillosis spp. and Cryptococcus spp. genera. In addition, increasing global populations leads to increasing agricultural demands. Thus, fungal infections of preharvested crops and stored food by plant pathogens such as Magnaporthe oryzae and Fusarium oxysporum can have detrimental socioeconomic effects due to food insecurity. Current antifungal strategies are based mainly on small molecule antifungal drugs. However, these drugs are limited by poor solubility and bioavailability. Furthermore, antifungal resistance against these drugs are on the rise. Thus, antimicrobial polymers offer an alternative antifungal strategy. Antifungal polymers are characterised by cationic and hydrophobic regions where the cationic regions have been shown to interact with microbial phospholipids and membranes. These polymers can be synthetic or natural and demonstrate distinct antifungal mechanisms ranging from fungal cell membrane permeabilisation, cell membrane depolarisation or cell entry. Although the relative importance of such mechanisms is difficult to decipher. Due to the chemical properties of these polymers, they can be combined with other antimicrobial compounds including existing antifungal drugs, charcoals, lipids and metal ions to elicit synergistic effects. In some cases, antifungal polymers and nanocomposites show better antifungal effects or reduced toxicity compared to the widely used small molecule antifungal drugs. This review provides an overview of antimicrobial polymers and nanocomposites with antifungal activity and the current understanding of their antifungal mechanisms.
Methanol Dehydrogenases as a Key Biocatalysts for Synthetic Methylotrophy
Authors: Le Thien-Kim , Lee Yu-Jin , Han Gui Hwan , Yeom Soo-Jin
Published: December 2021

One-carbon (C1) chemicals are potential building blocks for cheap and sustainable re-sources such as methane, methanol, formaldehyde, formate, carbon monoxide, and more. These resources have the potential to be made into raw materials for various products used in our daily life or precursors for pharmaceuticals through biological and chemical processes. Among the soluble C1 substrates, methanol is regarded as a biorenewable platform feedstock because nearly all bioresources can be converted into methanol through syngas. Synthetic methylotrophy can be exploited to produce fuels and chemicals using methanol as a feedstock that integrates natural or artificial methanol assimilation pathways in platform microorganisms. In the methanol utilization in methylotrophy, methanol dehydrogenase (Mdh) is a primary enzyme that converts methanol to formaldehyde. The discovery of new Mdhs and engineering of present Mdhs have been attempted to develop synthetic methylotrophic bacteria. In this review, we describe Mdhs, including in terms of their enzyme properties and engineering for desired activity. In addition, we specifically focus on the application of various Mdhs for synthetic methylotrophy.
Anti-Corrosion Mechanism of Parsley Extract and Synergistic Iodide as Novel Corrosion Inhibitors for Carbon Steel-Q235 in Acidic Medium by Electrochemical, XPS and DFT Methods
Authors: Wan Shan , Chen Huikai , Zhang Tian , Liao Bokai , Guo Xingpeng
Published: December 2021

The parsley extract (PLE) was prepared using absolute ethyl alcohol. The PLE and synergistic iodide were firstly utilized as efficacious corrosion inhibitors to slow down the corrosion rate of carbon steel-Q235 in 0.5 mol/L H2SO4 solution. The anti-corrosion performance was researched by weight loss method, electrochemical tests, surface analysis and quantum chemistry calculation. Results of electrochemical and weight loss tests show that the synergetic PLE and I− exhibit the optimal corrosion inhibition efficiency 99%. The combined inhibitor displays the favorable long-term corrosion inhibition effect, and the inhibition efficiency can maintain more than 90% after 144 h immersion. The introduction of I− makes carbon steel surface with higher negative charge amount, which could be beneficial to the interaction between corrosion inhibitor and Fe atoms. The adsorption behavior obeys the Langmuir isotherm adsorption, and involves chemical and physical adsorption. On the basis of electrochemical consequences and theoretical calculation, the adsorption process and anti-corrosion mechanisms are further explored.
LCK and CD3E Orchestrate the Tumor Microenvironment and Promote Immunotherapy Response and Survival of Muscle-Invasive Bladder Cancer Patients
Authors: Zheng Xiaonan , Liao Xinyang , Nie Ling , Lin Tianhai , Xu Hang , Yang Lu , Shen Bairong , Qiu Shi , Ai Jianzhong , Wei Qiang
Published: December 2021

Background: Studies have demonstrated the significance of multiple biomarkers for bladder cancer. Here, we attempt to present biomarkers potentially predictive of the prognosis and immunotherapy response of muscle-invasive bladder cancer (MIBC).

Method: Immune and stromal scores were calculated for MIBC patients from The Cancer Genome Atlas (TCGA). Core differential expression genes (DEGs) with prognostic value were identified and validated using an independent dataset GSE31684. The clinical implications of prognostic genes and the inter-gene correlation were presented. The distribution of tumor-infiltrating immune cells (TICs), the correlation with tumor mutation burden (TMB), and the expression of eight immune checkpoint–relevant genes and CD39 were accordingly compared. Two bladder cancer cohorts (GSE176307 and IMvigor210) receiving immunotherapy were recruited to validate the prognostic value of LCK and CD3E for immunotherapy.

Results: 361 MIBC samples from TCGA revealed a worse overall survival for higher stromal infiltration (p = 0.009) but a better overall survival for higher immune infiltration (p = 0.042). CD3E and LCK were independently validated by TCGA and GSE31684 to be prognostic for MIBC. CD3E was the most correlative gene of LCK, with a coefficient of r = 0.86 (p < 0.001). CD8+ T cells and macrophage M1 are more abundant in favor of a higher expression of CD3E and LCK in MIBC and across pan-cancers. Immune checkpoints like CTLA4, CD274 (PD-1), and PDCD1 (PD-L1) were highly expressed in high-CD3E and high-LCK groups for MIBC and also for pan-cancers, except for thymoma. LCK and CD3E had a moderate positive correlation with CD39 expression. Importantly, high-LCK and high-CD3E groups had a higher percentage of responders than the low-expression groups both in GSE176307 (LCK: 22.73vs. 13.64%, CD3E: 22.00 vs. 13.16%) and IMvigor210 cohorts (LCK: 28.19 vs. 17.45%, CD3E: 25.50 vs. 20.13%).

Conclusion: CD3E and LCK were potential biomarkers of MIBC. CD3E and LCK were positively correlated with several regular immunotherapy biomarkers, which is supported by real-world outcomes from two immunotherapy cohorts.