bluuebunny/crossref_metadata_2025 huggingface dataset:
Adrenoreactivity as a prognostic criterion of perioperative cardiac complications during extracardiac operations
Authors: Bulashova O V , Malkova M I
Published: November 2019

Aim. To study the adrenoreactivity of the organism and the possibility of using the value of β-adrenoreception of the erythrocyte membrane as a criterion for prediction of cardiac complications in the perioperative period during extracardiac operations. Methods. In 67 patients with acute cholecystitis and concomitant cardiac pathology requiring surgical treatment, assessed was the risk of cardiac complications according to the T.H. Lee index, and β-adrenoreception of the erythrocyte membranes according to the method of R.I. Stryuk and I.G. Dlusskaya. Three groups of patients were identified: with low, medium and high risk of cardiac complications. One month after the surgery the endpoints were studied: cardiac death, nonfatal myocardial infarction, stroke, disturbances of cardiac rhythm and conduction. Results. Perioperative complications, which presented in the form of paroxysmal atrial fibrillation and atrial flutter occurred in 8% of the patients of the medium risk group, and in the form of unstable angina in 12.5% of high risk patient group. Revealed were significant differences between the parameters of β adrenoreception of the erythrocyte membranes in patients with no risk and patients from medium and high risk groups. Established was a positive correlation between the value of β-adrenoreception of the erythrocyte membranes and the risk of perioperative cardiovascular complications. Conclusion. Revealed was a decrease of β-adrenoreactivity in patients with indications for surgery for acute cholecystitis with comorbid cardiovascular disease, which reflects the process of desensitization of adrenergic receptors of the cell membranes in the activity of neurohormones.
Thickness of the «Intima-media» complex of brachiocephalic vessels as a significant marker of coronary atherosclerosis in ischemic heart disease
Authors: Fedorov V S
Published: November 2019

Aim. To assess the correlation of the indices of the «intima-media» complex thickness of brachiocephalic vessels by ultrasound investigation and the degree of coronary stenosis by angiography. Methods. 239 patients with ischemic heart disease and a history of myocardial infarction participated in the study. An ultrasound investigation of brachiocephalic vessels and angiography of the coronary arteries was performed in all patients in the in-patient setting. Results. Among patients with a thickness of the «intima-media» in the range of 0.8-1.1 mm not a single case of coronary stenosis was registered. When the thickness of the «intima-media» complex was 1.3 mm or more the prevalence and extent of atherosclerotic lesions of coronary vessels increased proportionally. Conclusion. The evaluation of the «intima-media» complex thickness of the brachiocephalic vessels makes it possible to predict with high accuracy the prevalence of coronary atherosclerosis, as well as to monitor the effectiveness of the treatment of atherosclerosis.
The effectiveness of ursodeoxycholic acid and «Uvinskaya» mineral water in the treatment of cholelithiasis and concomitant motor-tonic disturbances of the gallbladder
Authors: Gorbunov A Yu , Vakhrushev Ya M , Rybin D S , Sharafutdinova D R , Suchkova E V
Published: November 2019

Aim. To optimize the conservative treatment of patients with cholelithiasis. Methods. Conducted was a comprehensive in-depth examination and treatment of 87 patients with gallstone disease (cholelithiasis) at the stage of biliary sludge (in the initial physicochemical stage - before stone formation) with associated hypokinesia of the gallbladder. The diagnosis was verified by the means of ultrasound investigation, multifractional duodenal probing and the intensity of biliary sludge was determined by the content of cholesterol, bile acids (spectrophotometrically) and cholate-cholesterol coefficient in the bile. The content of microelements in the bile was estimated by the method of atomic emission spectroscopy with inductively coupled plasma. The spectrum of bile acids in the bile was determined by the method of matrix laser desorption ionization. The acid-producing function of the stomach was evaluated by the means of intragastric pH-metry. During endoscopy investigation a targeted biopsy of the mucous membrane of the anterior and posterior walls of the stomach was performed, followed by morphological examination of biopsy specimens. The patients were divided into two groups. Sulfate sodium-calcium mineral water «Uvinskaya» (Udmurtia) and ursodeoxycholic acid (Ursosan) was used in the treatment of patients of the observation group. In the comparison group monotherapy with ursodeoxycholic acid at a dose of 15 mg/kg body weight was conducted. Hydrotherapy in the observation group was conducted for 24 days, while medicinal treatment in both groups was continued for another 2 months. The control group consisted of 15 practically healthy individuals. Results. In the course of treatment a marked decrease in the pain in the right hypochondrium, the disappearance or reduction of dyspeptic complaints, loss of echo-positive particulates in the gall bladder and an increase in its contractility was noted in all patients of the observation group, at the same time the signs of inflammation also disappeared and the cholate-cholesterol coefficient increased. Registered was a favourable dynamics of the content of microelements in the bile. Conclusion. The combined use of the «Uvinskaya» mineral water and ursodeoxycholic acid for the treatment of cholelithiasis with biliary sludge promotes the most rapid elimination of clinical symptoms of the disease, improves the functional state of the gall bladder, reduces the lithogenic properties and normalizes the content of microelements in the bile.
Justification of the diagnostic algorithm in determining the indications for pathogenetic therapy of dental caries
Authors: Gilyazeva V V , Giniyatullin I I , Muratova L D
Published: November 2019

Aim. To justify the importance of the diagnostic algorithm in the management of patients with dental caries. Methods. Summarized were authors’ personal and literature data on the factors and conditions of realization of a cariogenic situation, on the predictors of dental caries, as well as on the role of the diagnostic measures. Stressed was the significance of the physical status of the parents and of the normal course of pregnancy for optimal formation of organs and tissues of a child’s oral cavity, which predetermines the healthy dental status of the adult. Results. Presented was the diagnostic algorithm for dental caries, with an emphasis on the importance of assessing the state of local immunity of the oral mucosa, the need for obtaining primary anamnestic information. Outlined were the signs of salivary disorders that contribute to the formation of a cariogenic situation. The items presented in this article may serve as a basis for construction of a diagnostic algorithm for the management of patients with dental caries with the aim of for subsequent planning and implementation of effective pathogenetic therapy of the disease. Conclusion. The correctly selected diagnostic algorithm in the management of patients with dental caries allows the dentist to obtain objective information about the features of the emergence and development of the disease and to define the indications for pathogenetic therapy.
The effect of removable acrylic dental prostheses on immune homeostasis of the oral mucosa depending on the applied materials and structures
Authors: Pervov Yu Yu
Published: November 2019

Aim. To pathogenetically substantiate the effectiveness of performing prosthetic appliances of the dentition defects and predicting the results of occlusal rehabilitation of patients with pathology of the dental system based on the analysis of immune homeostasis of the oral mucosa. Methods. Examined were 39 people with secondary partial (I and II class according to Kennedy) and complete lack of teeth aged from 25 to 85 years, for whom removable acrylic dentures were manufactured. The control group included 18 people aged 20-85 years with abnormal dentition, requiring preliminary surgical preparation for prosthetics. Three age groups were identified: 20-40 years (first group), 40-60 years (second group), aged 60 and above (third group). Conducted was a morphological study of prosthetic bed biopsies obtained after 3, 6 and 12 months after returning the prostheses with immunohistochemical determination of markers for CD68, CD204, and CD163, with high specificity for dendritic cells, mast cells and macrophages, respectively, providing the immune homeostasis of the oral mucosa. For identification of intraepithelial lymphocytes determined was the expression of CD4 and CD8. In order to evaluate the intensity of regeneration of epithelial cells determined was the expression of the Ki-67 marker. Results. In the individuals of the first and second age groups noted was the predominance of dendritic, mast cells, CD4+ and CD8+. In patients of the third group the dynamics of the content of CD68+ and CD163+ cells in the mucosa of the prosthetic bed was less pronounced. A direct strong correlation relationship between the proliferation index and the number of CD68+, CD204+, CD4+, CD8+ cells, which provide the immune homeostasis of the oral mucosa in these patients, was established. A direct strong correlation relationship between the clinical changes in the oral cavity in the process of usage of the removable dentures and the absolute number of lymphocytes and dendritic cells in the inflammatory infiltrate was established. Revealed were the dynamics of changes in mitotic activity of keratinocytes in the process of usage of the removable dentures and the correlation of these parameters with the terms of use of the prostheses. Conclusion. The changes of the immune homeostasis parameters of the oral mucosa with this type of prosthesis can be considered a basis for pathogenetic substantiation of treatment and predicting the outcomes of occlusal rehabilitation of dental patients.
Indicators of the functional state of the autonomic nervous system in different age group patients with temporomandibular joint pain dysfunction syndrome
Authors: Silant’eva E N
Published: November 2019

Aim. To study the functional state of the autonomic nervous system and of the adaptative capabilities of the organism in patients of different age groups with temporomandibular joint pain dysfunction syndrome. Methods. The study included 234 patients with temporomandibular joint pain dysfunction syndrome (22 men and 212 women) aged 12 to 35 years, without anomalies of the dentition, who were divided into three age groups. Three control groups consisted of 30 healthy subjects (3 men and 27 women, 10 men in each age group) with intact dentition, and orthognathic bite. A clinical dental examination, and a multi-dimensional verbal-color pain test were conducted. In order to assess the functional status of the autonomic nervous system and the adaptive capacity of the organism used were the schemes of examination for detecting signs of autonomic disorders, a physicians questionnaire «Study Design for detecting signs of autonomic disorders», an autonomic test - «Questionnaire for detecting signs of autonomic changes for the patient» and a questionnaire, adapted for children and adolescents, cardiointervalography. Results. In all 234 patients with temporomandibular joint pain dysfunction syndrome revealed were the signs of autonomic dysfunction, possessing vagotonic features in 93.9% of the cases. An unbalanced condition of the autonomic nervous system in association with the temporomandibular joint pain dysfunction syndrome was registered significantly (p 0.05) more frequently in patients of the mature age group. According to cardiointervalography, in the patients revealed was a primarily vagotonic or hypersympaticotinic type of response, a significant predominance (p 0.05) of the functional stress adaptation mechanisms, mismatch of the processes that control heart rhythm until the breakdown of the adaptation mechanism. Conclusion. The revealed instability of the autonomic regulation and the features of autonomic responses in patients of different age groups with the temporomandibular joint pain dysfunction syndrome are necessary to consider when developing and selecting methods of pathogenetic therapy.
On improving medical care for patients with metastatic tumors of the central nervous system in the Republic of Tatarstan
Authors: Danilov V I , Khasanov R Sh , Alekseev A G , Shakirov K T , Nasher A A
Published: November 2019

Aim. To optimize medical care for patients with metastatic tumors of the central nervous system in the Republic of Tatarstan. Methods. The database of the Cancer Registry of the Republican Clinical Oncology Dispensary of the Ministry of Health Care of the Republic of Tatarstan and the case histories of patients treated in the neurosurgical departments for the period from 1998 to 2007 served as the material for this study. Results. Lung cancer, breast cancer, kidney cancer and melanoma were the most frequent types of cancers to metastasize to the central nervous system. There was a significant discrepancy between the predicted and the detected number of patients with metastatic lesions of the central nervous system. Studied was the quality of medical care provision to this category of patients. In the Republic of Tatarstan established is a modern instrumental base for the timely diagnosis of metastatic lesions of the central nervous system and their complex treatment in accordance with the current guidelines. However, the effectiveness of diagnostic and therapeutic measures still remains unsatisfactory. Conclusion. A set of measures for optimizing medical care for patients with metastatic tumors of the central nervous system has been developed in the Republic of Tatarstan.
Introduction of modern surgical methods of treatment of patients with fractures of the proximal femur
Authors: Akhtyamov I F , Kovalenko A N , Shigaev E S , Moiseyev M Yu , Khakimov M R , Gatina E B
Published: November 2019

Aim. To evaluate the qualitative and quantitative changes in the surgical approaches to the treatment of traumatic injuries of the proximal femur. Methods. Conducted was an analysis of the introduction of modern methods of surgical treatment of patients with injuries of the proximal femur for the period from 2004 to 2010. Discussed were the variants of osteosynthesis and endoprosthetic hip replacement for fractures of the neck and the trochanteric region of the femur in 1007 injured patients. Results. Over the period of 4 years it became possible to double the surgical activity of the trauma department through systematic personnel training and through the use of new structure-designs for osteosynthesis and arthroplasty. The main problem was recognized to be the lack of a system of surgical treatment and rehabilitation of such a complex group of patients. Conclusion. The analysis of results showed the need for development of specific standards of treatment of patients with fractures of the proximal femur both in Kazan city and at the level of the Republic of Tatarstan.
Endovasal laser vein obliteration in patients with varicose disease of the lower extremities in the ambulatory practice
Authors: Filippov V A , Shakirov M I , Kirshin A P
Published: November 2019

Aim. To evaluate the results of treatment of patients with varicose disease of the lower extremities using endovenous laser obliteration. Methods. Endovenous laser obliteration of the saphenous and perforating veins was used in the treatment of 72 patients with varicose disease of the lower extremities by applying a laser with a wavelength of 1.56 µm. The intervention technique included puncturing and catheterizing of the great saphenous vein or small saphenous vein under ultrasound angioscanning control followed by an introduction of the laser fiber-optic light guide and advancing it to the level of the saphenofemoral or saphenopopliteal junction. After paravasal introduction of the anesthetic solution the laser obliteration was performed under ultrasound control. Results. Postoperatively noted was the low intensity of pain, low severity of ecchymosis and no tenderness along the obliterated veins. No complications were recorded. 40 patients were examined in follow-up during the period from 2 to 4 months after the endovenous laser obliteration. The degree of obliteration of 39 great saphenous veins, 2 small saphenous veins and 8 perforating veins was evaluated. In all cases complete obliteration of veins subjected to laser exposure was noted, no abnormal refluxes or areas of preserved blood flow were revealed. Conclusion. The endovenous laser obliteration is a mini-invasive effective method of providing a complete occlusion of the blood vessel, which eliminates the vertical and horizontal pathological reflux in varicose disease of the lower extremities; this technique can be used in an outpatient setting.
Features of community-acquired pneumonia treatment with 3rd generation cephalosporins in combination with azithromycin and as monotherapy
Authors: Khamitov R F , Grigoreva I V
Published: November 2019

Aim. To refine the indications for oral administration of a combination of 3rd generation cephalosporins together with azithromycin and also as monotherapy in patients with moderate and severe community-acquired pneumonia. Methods. A questionnaire was developed to evaluate the clinical and laboratory data on the 1st, 3rd, 5th, 7th and 10-14th days of treatment. The patients were included in the study if clinical signs of pneumonia were present, the disease occurred outside a hospital, and if there was radiological verification of lung tissue infiltration. The study included 77 patients (32 women and 45 men) aged 16 to 84 years. In 56 patients (73%) pneumonia had signs of a moderate course, in 21 (27%) - a severe course. Results. As a result of treatment the number of patients without shortness of breath significantly increased. The difference in comparison with the time of hospitalization was statistically significant starting from day 7 of treatment in patients treated with ceftriaxone and azithromycin (31 and 69%, p 0.05). Intergroup differences also became significant on the same time since treatment initiation (43% of patients on monotherapy, p 0.05). The increase in the proportion of patients without shortness of breath, receiving only ceftriaxone in comparison with the beginning of treatment became significant only by the 10th day (18 and 54%, p 0.05). Conclusion. A combination antibiotic therapy is indicated for patients with a severe course of disease and clinically significant dyspnea, as well as for women with a moderate community-acquired pneumonia with a productive cough. No significant differences in the safety and tolerability of the studied variants of treatment options have been revealed.
Laparoscopic sanitation of the abdominal cavity in complex treatment of patients with generalized peritonitis
Authors: Malkov I S , Salakhov E K
Published: November 2019

Aim. To develop a method of programmed laparoscopic sanitation in patients with generalized forms of peritonitis with the use of low-frequency ultrasound energy. Methods. Conducted was an analysis of results of treatment of 211 patients with generalized peritonitis admitted to the surgical department of the City Clinical Hospital №7 from 2000 to 2010. The main group comprised 37 patients in whom laparoscopic sanitation with the use of low-frequency ultrasound was performed. The control group included 174 patients who underwent conventional relaparotomy due to progression of the pathological process in the abdominal cavity. Results. The proposed method of laparoscopic sanitation helped to reduce mortality by 12%, and the development of postoperative complications by 8% compared with control group in patients of the II stage of severity of peritonitis according to the Mannheim peritoneal index. Conclusion. The developed method of programmed videolaparoscopic sanitations of the abdominal cavity with the use of low-frequency ultrasound in patients with generalized peritonitis has a pronounced bactericidal and bacteriostatic effect.
Modern approaches to local treatment of pyo-necrotic complications of the diabetic foot syndrome
Authors: Slavin L E , Godzhaev B N , Zamaleev A Z
Published: November 2019

The analysis of publications devoted to modern methods of treatment of pyo-necrotic complications of diabetic foot syndrome has been presented. Identified were the most important principles of therapeutic tactics for this type of pathology. In order to create optimal conditions for wound healing after surgical sanitation local drug treatment is carried out - a thorough wound detersion with application of the isotonic sodium chloride solution or a neutral bathing solution, periodic (as needed) necrectomies, application of bandages, in accordance with the phase of wound healing process. The choice of medication for local treatment depends on the one hand on the type of lesion of the lower limbs, on the other - on the diabetes related morbidity and phase of wound healing. In the first phase of wound healing antiseptics are used: iodophors, polyhexanide (lavasept), hydroxymethyl quinoxaline dioxide (dioxidine), and in the absence of ischemia - compositions based on gelevine, water-soluble base ointments. In the second phase used were various wound covers based on collagen, as well as oil and hydrogel dressings. Ready-to-use bandages are also used, which are multi-layered system, comprised of a cellulose substrate, collagen, fibroblasts, growth factor, coated with plates of silicon to control humidity. The disadvantage of the ready-to-use dressings is the impossibility of controlling the wound on a daily basis. One of the trends in the treatment of chronic diabetic wounds is the use of living skin cells that serve as a source of growth factors, cytokines and other proteins that stimulate the healing process. The use of local immunomodulators is seen as promising. Treatment should be individualized and systemic antibiotic therapy is required. The main principle of local treatment is the creation of optimal conditions for accelerating the healing process.
Pathogenesis of atherosclerosis of arteries of the lower extremities: candidate genes and their polymorphism
Authors: Katina M N , Gayfullina R F , Valiullin V V , Rizvanov A A
Published: November 2019

Personalized medicine involves the use of genetic methods by physicians for early diagnosis, prediction of the nature of the disease course and the choice of medicines and their doses based on personalized characteristics of the individual patient. Advances in the study of the human genome make it possible to reveal the interrelation between different varieties of alleles of human genes (polymorphism) and predisposition to certain diseases. Currently there are more than 10 million single-nucleotide polymorphisms in the human genome, but their biological role remains poorly understood. On the basis of a literature search of electronic full-text and abstract-only versions of articles’, which was conducted in the PUBMED, OMIM and GENE databases, collected was the information on genetic predisposition to systemic atherosclerosis. The review is dedicated to polymorphisms of the major genes that play a role in the pathophysiology of atherosclerosis of the lower extremities.
Methodological justification of preparing medical workers of medical and preventive treatment institutions of the Republic of Tatarstan for providing medical care in the event of occurrence of centers of mass sanitary losses
Authors: Apechkin N N , Galiullin A N , Nureyeva E G
Published: November 2019

Aim. To optimize the training of medical personnel for providing emergency medical care to the general public. Methods. Socio-hygienic, statistical and experimental. A questionnaire-based survey was conducted among 450 medical doctors and 136 members of the nursing personnel in order to determine the subjective level of knowledge in the field of organizing medical evacuation procedures in the centers of mass sanitary losses. Conducted was an initial testing of 108 doctors and 106 members of the nursing personnel in order to objectively assess their level of knowledge followed by a final post-training test. A new technology for training health professionals has been developed and recommended for inclusion into the program of medical postgraduate education. Results. If the doctors prior to training had the level of preparedness to provide first medical care in centers of sanitary losses of 49.71%, then after training, this figure increased to 75.38% (p 0.001). Among the nursing staff the level of preparedness prior to training did not exceed 51.88% of the cases, while after the training it reached 74.28% (p 0.001). Thus, after training according to the proposed methodology the level of knowledge in organizing medical care to the affected casualties in centers of sanitary losses at the pre-hospital stage increased by 47.89% (p 0.001 for t=12.19). The survey of health professionals showed that 97.2% of health workers gave a positive evaluation of our proposed method of training. Conclusion. The proposed technology makes it possible to increase the level of training of medical personnel in organizing and delivering health care.
Safety in transfusiology
Authors: Alekseyev E B , Kravchenko T G
Published: November 2019

This article presents a list of investigations that need to be conducted before the procurement of preparations for blood transfusion. Analyzed were the results of the work in identifying bloodborne infections in the donor of the Central Military District of the Russian Ministry of Defence. Over the 3 years of work of the blood transfusion station of the 354th District Military Clinical Hospital identified were 36 people infected with hepatitis B, 56 - with Hepatitis C, 10 - with syphilis.
Principles of intensive treatment of pancreonecrosis
Authors: Alukov A Sh , Noskov I Yu
Published: November 2019

In the article based on the analysis of literature data and on authors’ personal experience presented were the main principles of conducting intensive medical therapy in patients with severe forms of pancreonecrosis.
Protecting the health of medical personnel in the light of prevention of nosocomial infections and occupational exposure
Authors: Ilyina N V
Published: November 2019

Prevention of nosocomial infections and occupational diseases among health care workers is an important component of the activity of the station for blood transfusion. This article outlines the directions and shows how this is prevention should be achieved.
Diagnosis and treatment of disseminated intravascular coagulation syndrome
Authors: Kemerov S V
Published: November 2019

Disseminated intravascular blood coagulation syndrome is a rather complex pathology, accompanied by multi-directional shifts in the overall haemostasis. This article presents the diagnostic algorithm and treatment strategy, depending on the stage of disseminated intravascular blood coagulation syndrome.
Prostaglandin E1 in vascular reconstructive operations in patients with diabetic foot syndrome
Authors: Koreyba K A , Maksimov A V
Published: November 2019

The article presents the results of using prostaglandin E1 in the perioperative period in patients with diabetic foot syndrome who underwent reconstructive operations on the blood vessels of the lower extremities. This method made it possible to optimize the treatment of this group of patient.
Extracorporeal methods of detoxication in the complex treatment hepatitis
Authors: Parfenchik F N , Kulidzhanov A Yu
Published: November 2019

Aim. To study the effectiveness of extracorporeal methods of detoxification in the complex treatment of hepatitis’. Methods. Observed were 39 servicemen who received treatment for viral hepatitis’ A, B and C, at the age of 18 to 40 years (in 13 people - a severe form of viral hepatitis A, in 3 - a moderate form of hepatitis A, in 18 - severe form, and in 5 - moderate form of hepatitis B and C). Diagnostic criteria for chronic viral hepatitis’ include data of virological, clinical, laboratory and morphological studies. Percutaneous needle biopsy of the liver made it possible to make a diagnosis during chronic viral hepatitis based on a histological study, to monitor the effectiveness of treatment, to exclude congenital metabolic liver disease. Results. On the background of administration of the traditional scheme of treatment (regimen, diet, interferon therapy, detoxification, metabolic support, glucocorticosteroids, immune stimulants, antihistamines, bile acid absorbents, adsorbents, cholagogues drugs, hepatoprotectors), the average duration of treatment of viral hepatitis was 30-45 days. During the usage of extracorporeal methods of detoxification (plasmapheresis and hemosorption) the duration of treatment was significantly shorter. Conclusion. The usage of extracorporeal detoxification methods can shorten the treatment of viral hepatitis A, B and C.
Analysis of quarantined donor plasma at the Republican blood transfusion station from 2009 to 2011
Authors: Rodionova O A , Kanaeva L P
Published: November 2019

With the aim of ensuring safety of transfusion of plasma and its products conducted is a deposit of the plasma with the prohibition of use for a certain period of time - plasma quarantine. The needs of medical institutions in the quarantined and inactivated plasma are met to the full extent.
The significance of extracorporeal hemocorrection in the treatment of disease of the therapeutic profile
Authors: Slizskiy V A , Kulidzhanov A Y , Arsent’ev O V
Published: November 2019

Aim. To evaluate the effectiveness of extracorporeal hemocorrection during a various spectrum of therapeutic diseases. Methods. To date we have conducted more than 10,000 operations of extracorporeal hemocorrection. The most widely used for therapeutic diseases was hemodialysis: during end-stage chronic kidney disease, temporary renal failure, caused by exacerbation of the underlying disease, poisoning with dialysing toxins, severe disorders of electrolyte composition of the blood, fluid overload with the development of pulmonary edema, severe endotoxemia. Results. Plasmapheresis played a major role in the treatment of somatic patients with dyslipidemia, obstructive jaundice, destructive pancreatitis, septic processes, liver failure and poisoning. Extracorporeal ultraviolet irradiation of blood was used mainly for pneumonia, gastric and duodenal ulcers, hyperthyroidism, viral hepatitis, neural infections, pyelonephritis, acute pancreatitis, burn disease, acute and chronic pyo-inflammatory processes of various locations. We have identified many disadvantages and complications during the usage of hemosorption and this narrowed down the indications of this method hemocorrection and detoxification. We believe the contraindications for hemodialysis to be cancers, uncontrolled arterial hypotension, ongoing internal bleeding; for the plasmapheresis - terminal condition of the patient, the lack of vascular access, uncontrolled arterial hypotension. Conclusion. The experience of extracorporeal hemocorrection gained in the clinics of Samara Military Medical Institute and continued within the setting of a hospital, requires further detailed investigation. Improvement of the above mentioned methods we assume to lead in the direction of their combined use.
The usage of a hydraulic model of the vascular system in the development of verification units for blood pressure measuring devices
Authors: Soyko A I , Karataev R N , Klyushkin I V , Gogin V A
Published: November 2019

The hydraulic model of the human circulatory system was discussed, presented from the position of classification and systematization of the major blood vessels, identified were the main consumers of the circulatory system, considered in detail was the area of regulation associated with the processes of blood pressure and heart rate measurement.
Infusion therapy in complex outpatient rehabilitation of patients with obliterating atherosclerosis of arteries of the lower extremities
Authors: Fattakhov V V , Nasrullaev M N , Maksumova N V
Published: November 2019

Infusion therapy in the outpatient setting holds the leading role in the treatment of patients with stages IIA and IIB of obliterating atherosclerosis of the lower extremities. In order to assess the risk of complications of infusion therapy used was a screening method for the analysis of heart rate variability using a complex of diagnostic functional changes in the cardiac rhythm, «Kardioanalizator “Expert 01”». Identification of patients taking into account the vegetative status according to heart rate variability (sympathetic-, normo- or parasympathotonia) makes it possible to adequately form group and individual rehabilitation programs, to determine the amount and time of treatment procedures, to predict possible complications. Infusion therapy, restoration of macro- and microcirculation is the basis of the effectiveness of rehabilitation programs for chronic arterial insufficiency of the extremities. In the implementation of treatment and rehabilitation programs the combination of arterial and venous systems disorders should be taken into account, as well as the need for concurrent correction of these changes.
The significance of electrothermometry indices for organization of adequate infusion therapy in diabetic foot syndrome
Authors: Fatykhov R I , Klyushkin I V , Akhmetyanov L A
Published: November 2019

Aim. To determine the criteria for conservative infusion therapy with the assessment of its effectiveness using the electrothermometry method. Methods. One of the major complications of diabetes is the diabetic foot syndrome. This diagnosis is established on the basis of clinical data and imaging studies. The resulting parameters are objective, but the specificity, selectivity, and the multiplicity of diagnostic procedures negate the effectiveness of these methods, making it difficult to consequently form treatment strategy. Registration of temperature parameters during different degrees of ischemic disturbances of the lower limbs by electrothermometry was performed with the subsequent formation of the algorithm of conservative therapy. Results. In patients with diabetic foot syndrome determined was the direct correlation between the degree of tissue ischemia of the lower extremities and the variation of temperature parameters. The formation of the course of conservative therapy was performed after evaluating the obtained parameters; its formation was based on the main pathogenetic links. Clinical data and the parameters of electrothermometry served as the method of dynamic control. Conclusion. Despite the achieved successes in the modern diagnosis of the diabetic foot syndrome, there still remains a number of inaccuracies, the key ones among then are the difficulties associated with determining the level of trophic disorders; electrothermometry makes it possible to expand the diagnostic horizons, and the obtained result can serve as a prognostic guide for the formation of the tactics of therapy and as a method of dynamic control.
Autotransplantation of immobilized stromal bone marrow cells during lumbar spondylosyndesis in an experiment
Authors: Kheifets M V
Published: November 2019

Aim. To assess the ability of immobilized autologous bone marrow stromal cells to provide an effective repair with the formation of a robust bone block in the area of the interbody defect of the spinal motor segment after total removal of the intervertebral disc. Methods. Studied were the effects of autotransplantation of different cell fractions isolated from the bone marrow (mononuclear, stromal cells and stromal stem cells) on the formation of the anterior bone block during interbody spondylosyndesis in an experiment on 24 mongrel dogs of different sexes (mean weight 18.3 kg, the mean diameter of the lumbar vertebral bodies according to radiographic study 18.6 mm). All animals underwent the crest puncture the right wing of the ilium, with aspiration of 10 ml of bone marrow, conducted was a total diskectomy at the level of the bodies of the VII and VIII lumbar vertebras with replacement of the interbody defect with a porous metal cylinder of the Nickel titanium of an appropriate shape and size. All animals were randomly divided into four groups, 6 in each. In the first group the interbody defect was filled with a porous metal cylinder only, in the second group - with the fraction of bone marrow mononuclear cells, in the third - with the fraction of stromal cells, in the fourth - with the fraction of culture-grown stromal cells. Results. In the first (control) group established were the signs of delayed formation of the anterior bone block, formation of the hypertrophic interbody pseudarthrosis. Noted was the formation of coarse fibrous capsule in the zone of «implant-bone» contact, an excess of cartilage tissue, the small size and low proliferative activity of osteoblasts, hypoplasia of the blood vessels. In the second group determined was the forming artificial bone block with paravertebral hyperostosis, radiologically - microdislocation of the implant with protrusion into the body of the adjacent vertebra and partial osteointegration with the porous structure of the fixer in the contact «implant-bone» zone. Bone formation occurred by the type of secondary osteogenesis with an excess of cartilage tissue. In the third and fourth groups formed was a robust artificial bone block, no signs of implant dislocation were observed. Determined was the full osteointegration of the porous structure of the fixer in the contact «implant-bone» zone. The newly formed bone tissue surrounded the implant in a muft-like fashion and grew into its porous structure, grew into the periosteal zone of adjacent vertebral bodies, well adhering with their surface. Conclusion. The proposed method of correction of osteoreparation disorders can be considered as an alternative to osteoplastic operations with the transplantation of massive bone grafts, as well as in conditions of systemic disorders of the ostepoetic function with a critical shortage of endogenous progenitors of bone cells.
Characteristics of oxygen carriers in modern blood substitutes
Authors: Shevchenko N V , Khudyakov S N , Zyryanov A A , Pyrenkov D A
Published: November 2019

Intraoperative and posttraumatic blood loss can be compensated by the introduction of crystalloid and colloid solutions. Blood transfusion is an effective method, but has several disadvantages: it may cause severe hemolytic reactions, infections and immune disorders. Blood substitutes based on oxygen-carrying molecules can solve most of these problems. The search for alternatives to donor blood and its preparations has continued for a long time, but only at this stage a few of the oxygen carriers have reached the phase of clinical trials. Artificial oxygen carriers are pharmacological agents used to improve oxygen delivery, regardless of the functions of erythrocytes, which perform solely a transport function of oxygen delivery. In this article, the authors have tried to reflect the current stage in the development, implementation and usage of oxygen carriers.
On the evacuation of the Imperial moscow educational home to Kazan during the Civil war of 1812
Authors: Albitskiy V Yu , Sher S A
Published: November 2019

The article presents the events that took place at the Imperial Moscow educational home during the Civil War in 1812, when Napoleon’s army entered Moscow. A description is provided of the period of evacuation of children older than 11-12 years of age to Kazan accompanied by doctors and other employees of the House, as well as the actions directly in the Educational home in Moscow, where young children had been left. Kazan became a shelter for the older children. Owing to the brilliant organizational abilities of the main supervising officer I.A. Tutolmin, to the high professionalism of the chief physician Kh. Oppel and to the doctors, who accompanied the evacuated children, as well as to the hospitality of Kazan city and the medical and pharmaceutical services of the city it was possible to avoid major outbreaks of infectious diseases and save the lives of many children.
List of scientific works of Aleksandr Aleksandrovich Baranov and of Valeriy Yurievich Al’bitskiy of child and neonatal mortality
Authors: - -
Published: November 2019

List of scientific works of Aleksandr Aleksandrovich Baranov and of Valeriy Yurievich Albitskiy of child and neonatal mortality
Investigating The Values of Guidance and Counseling in Eleganaboi
Authors: Da Costa Augusto , Goncalves Agostinho Dos Santos , Pereira Sebastiao , Moreira Paulo De Jesus
Published: November 2019

Abstract: Eleganaboi was a traditional ceremony in Luro society which contained essential elements of local wisdom. This study aimed to investigating the values of guidance and counseling in Eleganaboi. To investigate the values of guidance and counseling, we use phenomenology qualitative descriptive method. To collect the data, we implemented observation and interview. The observations were carried out during a cultural ceremony in the Luro community. Furthermore, interview was conducted on four traditional leaders. Edicts and transcendental reduction were used to analyze data. The results show eleven fundamental values of guidance and counseling in Eleganaboi. Those values are: gratitude; genuine; humble; honest; discipline; coherent; respect; care; trust; inclusive and togetherness. The community utilized Eleganaboi as a method to guide and counsel each member, including who faced problems in their life.Abstrak: Eleganaboi adalah upacara tradisional masyarakat Luro yang berisi unsur-unsur penting kearifan lokal. Penelitian ini bertujuan untuk mengeksplorasi nilai-nilai bimbingan dan konseling di Eleganaboi. Penelitian deskriptif kualitatif ini menggunakan pendekatan fenomenologi. Untuk mengumpulkan data, dilakukan observasi dan wawancara. Observasi dilakukan pada saat upacara budaya di masyarakat Luro berlangsung. Selanjutnya, dilakukan wawancara pada empat pemimpin tradisional. Reduksi eiditis dan reduksi transendental digunakan untuk menganalisis data. Hasil menunjukkan ada sebelas nilai dasar bimbingan dan konseling di Eleganaboi. Nilai-nilai itu adalah: rasa terima kasih; tulus; rendah hati; jujur; disiplin; koheren; hormat; peduli; percaya; inklusif; dan kebersamaan. Masyarakat Luro menggunakan Eleganaboi sebagai metode untuk membimbing dan menasihati setiap anggota mereka, termasuk mereka yang sedang menghadapi masalah dalam hidup.
Keefektifan Teknik Drama Segitiga Karpman untuk Meningkatkan Keterampilan Empati Siswa Sekolah Menengah Pertama
Authors: Latifah Leny
Published: November 2019

Abstract: Empathic skills encourage an individual to look into the problems more clearly and objectively. Without empathy, it is difficult to know what others are experiencing because it is not possible to feel and understand the conditions of others. The particular study aimed to determine the effectiveness of Karpman drama triangle technique to increase junior high school students’ empathy skill. The research subjects were six students of eighth grade in Sekolah Menengah Pertama Negeri 1 Turen, Malang. The particular research was Quasi-Experiment using the pretest and posttest design. The instruments were student empathy scale; experimental guidelines; and observation guidelines. The study showed that Karpman drama triangle technique was effective to increase junior high school students’ empathy skill.Abstrak: Keterampilan berempati mendorong seseorang untuk melihat permasalahan dengan lebih jernih dan objektif. Tanpa berempati, sulit untuk mengetahui apa yang sedang dialami orang lain karena tidak dapat merasakan perasaan dan memahami kondisi yang sedang dialami orang lain. Penelitian ini bertujuan mengetahui keefektifan teknik drama segitiga Karpman untuk meningkatkan keterampilan empati siswa sekolah menengah pertama (SMP). Subjek penelitian adalah enam siswa kelas delapan SMP Negeri 1 Turen, Malang. Penelitian ini merupakan penelitian Quasi Eksperimen dengan menggunakan desain pretest dan posttest. Instrumen yang digunakan adalah skala empati siswa; pedoman eksperimen; dan pedoman observasi. Hasil penelitian menunjukkan bahwa teknik drama segitiga Karpman efektif untuk meningkatkan keterampilan empati siswa SMP
Erratum untuk: Pengembangan Aplikasi Assessment Menggunakan Media Short Message Service
Authors: Hanggara Guruh Sukma , Andrianie Santy , Ariyanto Restu Dwi
Published: November 2019

Kami memohon maaf atas kesalahan penulisan Digital Object Identifier (DOI) pada artikel dengan judul Pengembangan Aplikasi Assessment Menggunakan Media Short Message Service. DOI artikel yang tertulis “https://doi.org/10.17977/um001v3i42018p146“ pada halaman 146 di bagian cara merujuk, seharusnya tertulis: https://doi.org/10.17977/um001v3i32018p146. Artikel asli telah diperbaiki.
Keefektifan Achievement Motivation Training untuk Meningkatkan Motivasi Berprestasi Siswa Sekolah Menengah Pertama
Authors: Putra Edwindhana Mareza , Handarini Dany M. , Muslihati Muslihati
Published: November 2019

Abstract: The particular study aimed to determine the effectiveness of achievement motivation training (AMT) in increasing the achievement motivation of junior high school students. The study used an interrupted time-series design which conducted on an intact group consisting of eight subjects. Data measurements carried out three times in the pre-test and post-test conditions with six forms of achievement motivation scale. The AMT intervention in the psychoeducation frame consists of two strategies, namely achievement thinking and action strategies which are carried out in 12 sessions. The results showed that there is a difference between achievement motivation scores before and after AMT interventions.Abstrak: Penelitian ini bertujuan untuk mengetahui keefektifan achievement motivation training (AMT) dalam meningkatkan motivasi berprestasi siswa sekolah menengah pertama (SMP). Penelitian ini menggunakan desain interrupted time series yang dilakukan pada kelompok intak yang terdiri dari delapan subjek. Pengukuran data dilakukan sebanyak tiga kali pada kondisi pre-test dan kondisi post-test dengan enam bentuk skala motivasi berprestasi. Intervensi AMT dalam bingkai psikoedukasi terdiri dari dua strategi yaitu achievement thinking dan action strategies yang dilakukan dalam 12 sesi pertemuan. Hasil menunjukkan terdapat perbedaan antara skor motivasi berprestasi sebelum dan sesudah diberikan intervensi AMT.
Pengaruh Kecerdasan dan Minat Pribadi Sosial terhadap Penyesuaian Diri Mahasiswa Bimbingan dan Konseling
Authors: Sari Nina Permata , Jamain Ririanti Rachmayanie
Published: November 2019

Abstract: The objective of this research is to identify the influence of intelligence and social self interest on the adaptation skill of the department of guidance and counseling students. This quantitative research used the multiple regression analysis. It used purposive total sampling technique, with sample of 38 students of Department of Guidance and Counseling, Faculty of Teacher Training and Education, Universitas Lambung Mangkurat (ULM). The results show that intelligence and social self interest of the department of guidance and counseling students simultaneously influence the adaptation skill of 35.9%, while the remaining 64.1% is influenced by other factors.Abstrak: Tujuan penelitian ini adalah untuk mengetahui pengaruh kecerdasan dan minat pribadi sosial terhadap penyesuaian diri mahasiswa jurusan bimbingan dan konseling. Penelitian kuantitatif ini menggunakan teknik analisis regresi berganda. Teknik sampling menggunakan teknik purposive total sampling, dengan sampel berjumlah 38 orang mahasiswa Jurusan Bimbingan dan Konseling, Fakultas Keguruan Ilmu Pendidikan (FKIP), ULM. Hasil menunjukkan kecerdasan dan minat pribadi sosial mahasiswa jurusan bimbingan dan konseling secara bersama-sama memengaruhi penyesuaian diri sebesar 35,9%, 64,1% sisanya dipengaruhi oleh faktor lain.