bluuebunny/crossref_metadata_2025 huggingface dataset:
Piperacillin-tazobactam fixed dose combination induced skin reaction in a patient with split thickness skin grafting: a case report
Authors: Solanki Vaibhav , Sinha Anita , Rathva Trushti , Kanjariya Dilip
Published: October 2024

Piperacillin is a semi-synthetic ureido-penicillin. It has a broad spectrum against gram negative bacilli particularly P. aeruginosa. It is one of the most broadly active of the currently available penicillin with regard to other bacterial species like proteus, klebsiella, H. influenzae and gonococci. Tazobactam is β-lactamase inhibitor and combined with piperacillin to increase spectrum of the drug. Patient was 25 years old female, admitted in orthopaedic department for treatment of traumatic leg injury of left limb. Leg was amputated in the accident, so after 1-month split thickness skin grafting was done at plastic surgery department. For prophylaxis piperacillin-tazobactam IV 4.5 gm 8 hourly given, on 2nd post operative day patient reported rashes on neck, trunk, both upper and lower extremities, sparing the mucous membrane. Patient was prescribed anti pruritic and anti-allergic medication for ADR management. It is necessary to use such kind of drugs cautiously in patients whose health is deteriorated by this medication.
Drug resistance profiling, antimicrobial susceptibility and demographic characteristics of children with acute bacterial meningitis in a Southeastern tertiary health facility
Authors: Nwala Chuks G. , Izuka Oluchi M. , Chidomere Ifeyinwa Roseann , Ogbonna Ikechukwu Frank , Kalu Ichie Eziyi , Ukpabi Ihuoma Kathleen
Published: October 2024

Background: Over the years, varying patterns of bacterial susceptibility and multidrug resistance (MDR) rates have been reported in different settings. Detailed evaluation of the drug profile of the bacterial pathogens implicated in children with invasive bacterial infection helps to reduce the heightened risk of adverse events that could follow poorly managed or complicated cases in resource limited environment like ours. This study therefore, aimed to highlight the antibiotic susceptibility and MDR rate, and establish the relationship if any, between demographic characteristics and positive CSF- bacterial isolates of post neonatal children with suspected acute bacterial meningitis (ABM). The findings would guide practitioners on the empirical antimicrobials to consider in the event of clinical suspicion of ABM pending the availability of CSF isolates' antibiogram.
Methods: A prospective review of 100 children with clinical suspicion of ABM from January 2016- December 2020. Descriptive statistics, chi square and regression analysis were used to establish MDR rates, Isolates' susceptibility pattern and the relationship between demographic variables and positive isolates respectively. P<0.05 was accepted as significant.
Results: Fluroquinolones, cephalosporins, imipenem and aminoglycosides were susceptible anti-microgram in children with ABM. Sixty-four (85.5%) of the isolates showed MDR pattern, and young children (infants and toddlers) were significantly associated with positive CSF bacterial isolates.
Conclusions: ABM should be treated with combination of CNS penetrating empirical antibiotics due to rising rate of MDR pathogens. Young children with febrile illnesses should be thoroughly evaluated for possibility of CNS infection.
Cancer survivorship and long-term outcomes: navigating the challenges beyond treatment
Authors: Tali Tavseef Ahmad , Amin Fiza
Published: October 2024

The increasing number of cancer survivors due to advancements in early detection and treatment has shifted the focus of oncology to the long-term health and well-being of these individuals. Cancer survivorship encompasses a wide range of challenges that extend beyond the completion of treatment, including physical, psychological, social, and economic issues. This review explores the long-term physical health consequences of cancer treatment, such as neuropathy, cardiotoxicity, and chronic conditions, and highlights the psychological burdens, including anxiety, depression, and cognitive impairment, commonly faced by survivors. The article also addresses the social and economic impacts, such as difficulties in returning to work and financial toxicity, which further complicate the survivorship experience. Additionally, the review emphasizes the importance of assessing and improving the quality of life (QoL) for survivors through personalized interventions and the implementation of survivorship care plans (SCPs). Emerging research on biomarkers, telemedicine, and policy advocacy is discussed as critical components for advancing survivorship care. The review concludes that a comprehensive approach, including ongoing research, personalized care, and supportive policies, is essential to meet the diverse needs of cancer survivors and improve their long-term outcomes and QoL.
El lado humano de la innovación
Authors: Tello Berenstein Alicia , Manrique Gutiérrez Daisy
Published: October 2024

¿Quién no ha jugado con el Empresario, divertido juego de simulación empresarial basado en la realidad de las Pymes del Perú? El Ingeniero Javier Zapata Innocenzi, editor y gerente de la editorial Malabares, orientada a la creación de material pedagógico y juegos, nos cuenta sobre el desarrollo de la innovación como vehículo para la difusión de la cultura y del conocimiento.
Perspectives of Defining Algorithmic Fairness in Customer-oriented Applications: A Systematic Literature Review
Authors: Maw Maw , Haw Su-Cheng , Ng Kok-Why
Published: October 2024

Automated decision-making systems are massively engaged in different types of businesses, including customer-oriented sectors, and bring countless achievements in persuading customers with more personalized experiences. However, it was observed that the decisions made by the algorithms could bring unfairness to a person or a group of people, according to recent studies. Thus, algorithmic fairness has become a spotlight research area, and defining a concrete version of fairness notions has also become significant research.  In existing literature, there are more than 21 definitions of algorithmic fairness. Many studies have shown that each notion has an incompatibility problem, and it is still necessary to make those notions more adaptable to the legal and social principles of the desired sectors. Yet, the constraints of algorithmic fairness for customer-oriented areas have not been thoroughly studied. This motivates us to work on a systematic literature review to investigate the sectors concerned about algorithmic fairness as a significant matter when using machine-based decision-making systems, what are the well-applied algorithmic fairness notions, and why they can or cannot be directly applicable to the customer-oriented sectors, what are the possible algorithmic fairness constraints for the customer-oriented sectors.  By applying the standard guidelines of systematic literature review, we explored 65 prominent articles thoroughly. The findings show 43 different ways of algorithmic fairness notions in the varieties of domains. We also identified the three important perspectives to be considered for enhancing algorithmic fairness notions in the customer-oriented sectors.
Deep Learning-based Method in Multimodal Data for Diabetic Retinopathy Detection
Authors: Wardhani Kartina Diah Kesuma , Kasim Shahreen , Erianda Aldo , Hassan Rohayanti
Published: October 2024

Diabetic retinopathy (DR) is a complex condition, and incorporating information from multiple sources, such as patient history, laboratory results, or genetic data, can enhance understanding. An ophthalmologist or an automated system can identify DR through manual examination. The automatic detection of diabetic retinopathy has become a preferred choice for patients and healthcare providers due to its cost-effectiveness and time efficiency. The novelty of this research lies in developing a model for predicting diabetic retinopathy using multimodal data fusion, incorporating fundus retinal images, optical coherence tomography (OCT), and electronic health records (EHR) through an early fusion technique implemented in a Long Short-Term Memory (LSTM) network. Our model, which utilizes an early fusion of multimodal data with Local Binary Pattern (LBP), has demonstrated the best performance, achieving an AUC value of 0.99. This high accuracy indicates that integrating information from various data sources can significantly improve the capability of the model in detecting both positive and negative cases of diabetic retinopathy, instilling confidence in the reliability of our findings.
Construing National and Ethnic Groups Under the Genocide Convention Through Soviet and Russian Narratives on the Ukrainian Identities
Authors: Vishchyk Maksym
Published: October 2024

Debates on the genocidal nature of Russian atrocities in Ukraine have uncovered various grey zones of the law on genocide. While most contemporary commentaries have focused on the essence and scope of the crime’s central element – the intent to destroy the group in whole or in part – little analysis has been dedicated to defining and understanding the alleged object of the destruction, i.e., protected groups themselves. Even beyond the Ukrainian context, this problem is endemic to contemporary doctrine and jurisprudence, providing a rather cursory or even contradictory analysis of the notions of protected groups seemingly without recourse to other fields studying human identities, such as anthropology. This article aims to address this lacuna by exploring the dichotomy between national and ethnic groups under the Genocide Convention through Soviet and Russian identity narratives. The article summarises the state of contemporary law and jurisprudence relevant to the definition of the protected groups, as well as associated gaps and inconsistencies. It further addresses challenging issues of the groups’ definition and delimitation through the lenses of modern anthropology, where the law is silent. The article stresses the importance of multidisciplinary and contextualised application of the legal concepts under the law of genocide in light of the meaning ascribed to them by other fields of study focusing on group identities and inter-group dynamics. Finally, the article applies relevant findings to the context of Soviet and further Russian narratives on the Ukrainian identities, illustrating the dichotomy between national and ethnic groups.
Differentiation of Powers of the Judiciary and the Constitutional Court of Ukraine in the Application of the Constitution as an Act of Direct Effect
Authors: Holiev Oleh
Published: October 2024

One of the conditions for effective interaction between the judiciary and the Constitutional Court of Ukraine is a clear determination and differentiation of their powers in the application of the Constitution of Ukraine as an act of direct effect. This differentiation helps to avoid duplication of powers, thereby contributing to the coordinated activities of these authorities and ensuring legal certainty. Therefore, the article examines the issues related to the differentiation of powers between the judiciary and the Constitutional Court of Ukraine in the application of the Constitution of Ukraine as an act of direct effect.The research focuses on the amendments to the Constitution of Ukraine in 2016 (on justice) and the reform of procedural legislation at the end of 2017. These amendments established a new mechanism of direct application of the Constitution of Ukraine by the judiciary, creating new challenges not only in terms of interaction but also in the differentiation of powers between the judiciary and the Constitutional Court of Ukraine. In the context of these changes, the author substantiates the differentiation of powers to verify legal acts for contradiction and compliance with the Constitution of Ukraine, as well as constitutionality, and formulates a definition of the relevant powers.It is concluded that the judiciary is responsible for the verification of a legal act’s contradiction to the Constitution of Ukraine, while the Constitutional Court of Ukraine is responsible for the verification of its compliance (constitutionality). The ground for verifying the constitutionality of an act is an appeal of an authorized subject to the Constitutional Court of Ukraine. The basis for the judicial authorities to verify a legal act for contradiction is a motion of a party to a case or the initiative of a court in civil, commercial, or administrative cases in which such a legal act is to be applied. The legal consequences of a contradiction of a legal act include the non-application of such an act in a particular case without the loss of legal force, except for normative acts adopted before the entry into force of the Constitution of Ukraine, as they are valid to the extent that they do not contradict it. In contrast, the recognition of a law or other act as noncompliant with the Constitution (unconstitutional) results in the invalidation of such an act from the date of the Constitutional Court’s decision, unless otherwise provided by the decision itself, but not earlier than the date of its adoption.It is proved that it is necessary to review the position that the courts are authorized to recognize acts non-compliant with the Constitution of Ukraine, which the Constitutional Court of Ukraine does not verify within the framework of constitutional proceedings.
Legal Regulation of the Provision of Social Services in the European Union
Authors: Ivanyshyn Ihor
Published: October 2024

The article examines the issues of legal regulation of the EU provision of social services in the Member States. Special attention is paid to the problems and needs of developing common approaches to social security, including social services, considering international and regional European standards in this area.The author provides several main approaches to the definition of the concept of social services in the legal space of the EU, which are as follows: social services from the point of view of their providers, social services from the point of view of recipients (addressees) of such services, social services as a common good of public interest. The article emphasises the priority of a human-centred approach to the understanding and legal regulation of social services under EU law. Therefore, the main approach to the standardisation of social services should be their understanding from the recipients’ point of view.The article supports the thesis that harmonisation in the field of social security, including social services, is extremely complicated by differences in national systems. Therefore, the science of social security and EU legal acts is about coordination, not harmonisation of social security.The means of coordinating, harmonising, and preventing conflicts of norms in social security law between EU Member States and third countries include not only international and regional social standards but also the conclusion of relevant bilateral agreements.The author states that it is also necessary to develop and implement European standards and approaches to providing social services in Ukraine not only by state institutions but also by non-governmental organisations and private service providers, which is actually provided for by the legislation of Ukraine on social services. The Social Code of Ukraine, the draft of which is currently being actively developed, should be an important step in the development of legal regulation of social security and its coordination with EU law.
Judicial System Reform in Albania in the Context of Accession Process to the European Union
Authors: Kolotylo Mykola
Published: October 2024

This article examines the reform of the justice system in Albania since 2016 through the lens of the accession procedure to the European Union and the practice of the European Court of Human Rights in individual cases against Albania. The first part is devoted to the analysis of the general context in which the reform of the justice system in 2016 was implemented in Albania and examines its main elements. The relevant reports of the European Commission regarding Albania are considered in this part with a focus on recommendations concerning the judiciary.The second part analyses the key judgements of the European Court of Human Rights regarding the process of reforming the justice system in Albania since 2016 based on individual applications of judges and prosecutors who were dismissed from their positions as a result of the re-evaluation procedure. These judgements include the following cases: Besnik Cani v. Albania, Gashi and Gina v. Albania, Nikëhasani v. Albania, Sevdari v. Albania, and Xhoxhaj v. Albania. In particular, the following aspects were considered: the status of bodies created to reassess judges and prosecutors, their independence and impartiality; as well as the proportionality of the interference in the private life of the applicants.Finally, the article aims to assess the impact of judgements in specific cases of the European Court of Human Rights on the accession procedure of Albania and other candidate states to the European Union. The article scrutinizes the reports of the European Commission regarding other candidate states in terms of the recommendations provided related to the judiciary and the rule of law. The article demonstrates the interrelation between the accession process to the European Union and the relevant judgements of the European Court of Human Rights analysing the judgements and key reports concerning other candidate countries. In particular, the reports of the European Commission concerning Georgia, Moldova, and Ukraine are considered. It is argued that the conclusions obtained in individual cases regarding the reform of the justice system in Albania should be interpreted in a much broader context of the procedure of accession tothe European Union of other candidate states.
Personalized Data Insights: How­­ Machine Learning is Revolutionizing Everyday Business Decisions
Authors: Kamdem Yves Stephane
Published: October 2024

The rise of machine learning has fundamentally transformed the way businesses approach decision-making, particularly in the realm of data analytics. In today’s data-driven landscape, organizations are not just gathering information—they’re using advanced algorithms to turn raw data into personalized, actionable insights that drive business strategy. Machine learning enables businesses to go beyond surface-level trends and dig deeper into customer behavior, operational inefficiencies, and market dynamics. This technology is revolutionizing everyday business decisions by delivering real-time, data-driven intelligence that is specifically tailored to each business's unique needs.
By leveraging machine learning, businesses can analyze massive datasets, uncover hidden patterns, and make predictions that were previously unimaginable with traditional analytics methods. One of the key benefits of machine learning is its ability to personalize data insights, offering businesses a clearer, more detailed understanding of their customers and operations. It empowers companies to make more accurate decisions in marketing, product development, customer service, and beyond, leading to improved efficiency, customer satisfaction, and overall business performance.
This article explores the transformative role of machine learning in generating personalized data insights and its profound impact on everyday business decisions. It highlights how this technology can improve decision-making processes, enhance customer experiences, and drive more effective business strategies through real-time analysis and prediction. Through practical examples, we will demonstrate how businesses across various sectors are already using machine learning to revolutionize their operations and improve outcomes.
Caminhos históricos para uma prática de ensino lúdica na Primeira República (1889-1930)
Authors: Soares Sâmia Regina Barros , Castellanos Samuel Luis Velázquez
Published: October 2024

Neste artigo, regatam-se práticas de ensino propostas a partir de indícios em documentos legais que apontem para o papel do lúdico no processo pedagógico, embora a limitação do termo ludicidade nos registros seja explícita durante a Primeira República. Usa-se o método histórico, a pesquisa bibliográfica e a documental como metodologia de trabalho: a primeira, para refletir sobre o conceito de ludicidade e sua importância nas práticas pedagógicas, auxiliando-nos em autores como Rau (2013); Ferreira (2009); Silva (2015) e Kishimoto (1990); a segunda, para o cruzamento de dados oriundos de propostas de ensino desenvolvidas em vários documentos: a 1ª Conferência Interestadual de 1921, onde se discutem novas estratégias para ensinar, inspiradas em programas/métodos estrangeiros, para promover um sistema educacional que combatesse o analfabetismo; o Congresso Pedagógico de 1920, que via exposições de diferentes autores jogos e brincadeiras são tratados como atividades essenciais na aprendizagem; em As Crianças (1909), de Laura Rosa, que recompila a Conferência realizada na Biblioteca Pública do Estado do Maranhão centrada em novas concepções sobre criança, infâncias, escola e educação, explorando vivencias e expectativas sociais para compreender o processo pedagógico e; no Livro de Lúcia (1933) de Rosa Castro, cujos escritos para professores do ensino primário possibilitam analisar novas práticas pedagógicas em detrimento dos modos tradicionais de ensino. Conclui-se que a ludicidade nunca esteve em pauta no campo educacional brasileiro na época com as finalidades que se lhe outorga atualmente, mesmo que se procurassem suportes inovadores que auxiliassem os professores no processo de ensino e aprendizagem das crianças.
Ser incluído e incluir:
Authors: Wellichan Danielle da Silva Pinheiro , Aquino Claire Cascaes de
Published: October 2024

Entrevista com a bibliotecária Claire Cascaes de Aquino, que tua na Biblioteca do IFSC - Campus Palhoça Bilingue. Auto considerada como uma bibliotecária cyborg surda oralizada, mantem perfil em redes sociais com importantes informações a respeito das pessoas com deficiência.
Comprehensive Assessment of Animal Welfare Standards in Small Pig Farms of Assam
Authors: Goswami Anabil , Barua Rashmita
Published: October 2024

Background: Assam's scenic landscapes and rich agricultural heritage are intertwined with traditional piggery practices, which hold cultural and economic significance, particularly among tribal communities. Questions about animal welfare standards within these traditional setups linger despite their communal ethos. Evaluating their impact is vital for sustainable farming, rural livelihoods, and ecological preservation. Methods: The study designed and applied a rigorous methodology that assessed animal welfare standards in Assam's pig farming. It involved a two-part study design, which included selecting the relevant indicators for conducting the study and assessing small pig farms across the different agro-climatic zones of Assam. Data collection from small-pig farmers across Assam's zones using a 5-point Likert scale was followed by descriptive statistical analysis. Result: Housing facilities in Assam's pig farms provide ample space, fostering positive social dynamics and natural behaviours. However, tethering remains a concern, limiting movement and behaviour expression. While pigs were not found to be overly thin or emaciated, feeding practices could be improved for optimal growth and ideal body score. Limited veterinary involvement poses challenges in managing health issues. Recommendations include avoiding tethering, optimising feed, enhancing collaboration with veterinarians, and ensuring comfortable quarantine areas to promote pig welfare and health.
In adult dogs is supplementary tryptophan in the diet effective in reducing signs of anxiety?
Authors: Sofyan Lesca
Published: October 2024

Question
In adult dogs, is dietary supplementation with tryptophan compared with no dietary tryptophan supplement effective in reducing signs of anxiety?
 
Clinical bottom line
The category of research question was:
Treatment.
The number and type of study designs that were critically appraised were:
Two studies were found to be considered appropriate in the level of hierarchy of evidence pyramid. One study was a randomised double-blinded, placebo-controlled study and the other was a single-blind, placebo-controlled study.
Critical appraisal of the selected papers meeting the inclusion criteria collectively provide zero/weak/moderate/strong evidence in terms of their experimental design and implementation:
Moderate.
The outcomes reported are summarised as follows…
One study found no overall significant influence of tryptophan in the diet as an aid in reducing anxiety and fear-related behaviour in anxious dogs in household conditions. In contrast, the second study reported lower anxiety-related behaviour in dogs by owners but did not find significant differences in cortisol levels based on urine cortisol-to-creatinine ratio.
In view of the strength of evidence and the outcomes from the studies the following conclusion is made…
Current evidence reveals two studies that have evaluated the effectiveness of tryptophan as a supplement to the diets of anxious canines for pet owners. One study conducted did not find a significant effect or interaction in reducing anxiety-related behaviour whilst the second study reported lower anxiety-related behaviour in dogs by owners but did not find significant differences in cortisol levels based on urine cortisol-to-creatinine ratios. The use of tryptophan as a supplementary component in the diet is thus not enough as a sole treatment to assist in reducing anxiety in anxious adult dogs.
Uso del Expediente Clínico Electrónico en Morelos México: Percepción de los proveedores de salud
Authors: Parada-Toro Irene , Rosas-Castán Irma Lilia , Rico-Alba Israel
Published: October 2024

Objective: To evaluate the factors related to the use of the Electronic Medical Record(ECE) from the perception of medical users of health services Morelos, Mexico.Material and methods: The qualitative analysis of 22 semi-structured interviewswith medical personnel, nurses, managers and administrators of a 2nd level hospital inMorelos, Mexico was carried out, taking as a reference for analysis the dimensions ofregulations, operability and training in the implementation of the ECE.Results: An insufficient number of computers and trained personnel were identified tooperate the ECE. When it is possible to operate the file, it is slow or presents frequentsystematic failures due to the navigation networks, they depend on the central browserthat provides state support to the ECE platform without a prompt resolution whenthere are failures, the hospital units work 24 hours and centrally. ECE operations have8-hour hours from Monday to Friday. This increases resistance to adopting the file as aworking tool. The organization contributes to the resistance by not providing sufficientand permanent technical support to face the operational failures of the ECE. Usersconsider that the file is safe and reliable, which would increase the possibility of usingthe ECE.Conclusions: The lack of resources and inefficiencies in the operation of the ECEcontribute to a low and slow adoption of the file; as well as the resistance to use it.The organization helps increase resistance if training is not efficient. Lack gives youcontinuous and sufficient support in the technical infrastructure and human resources.Despite the limited and inefficient adoption of ECE, areas and personnel were identifiedwhere there is greater use (hospitalization and medical personnel). These could bepositive learning experiences that can be used to educate the entire organizationKeywords: Electronic Medical Record; Utilization
Percepciones asociadas a conductas sexuales de riesgo
Authors: Rodriguez-Perez Luis Fernando , Becerra-Hernández Antonio
Published: October 2024

Objective: To identify youth perceptions associated to risky sexual behaviors in a group of teenagers from Tabasco.
Material and methods: It is a mixed, cross-sectional study with a non-probabilistic sampling which was carried out at the convenience of 60 people who met the inclusion criteria (18-25 years old) belonging to the state of Tabasco, consisting of 30 women and 30 men. Health and sexual habits surveys were applied to them.
Results: Women indicated doctors (30%) and their mothers (23%) as their main sources of sexual education; while, in the group of men, they referred to doctors, friends, books, etc. For the perception of risk of acquiring HIV with current sexual behavior, men perceived a higher risk of infection in comparison to women. In relation of measures that protect against HIV, the use of condoms was identified as the safest method, both in men (96.66%) and in women (100%). The second safest option they referred to was “to get tested frequently”; however, 65% reported never having an HIV test in the past. Regarding the use of condoms, in both groups, responses predominated, such as, “they are difficult to use”, “they create mistrust in the partner”, among others. Concerning about the perception of mechanisms through which HIV could be acquired, 60 participants (100%) indicated that HIV is transmitted through sexual intercourse; however, the option “by mosquito bite” was chosen by 3 men (10%) and one woman (3.33%).
Conclusions: Wrongful perceptions can be decisive in the practice of unsafe sexual practices. Identifying misperceptions, sources, quality and veracity of information on sexuality issues, as well as risk and protective factors, can be useful to design efficient psychoeducational interventions as a prevention strategy for adolescents and the youth.
Keywords: Perceptions; Sexual experience; Risky sexual behaviors; Sources of information.
Síntomas espirituales de adultos mayores en tiempos de pandemia por COVID-19
Authors: Duque Paula , Campiño-Valderrama Sandra Milena , Castañeda-Hidalgo Hortensia
Published: October 2024

Objective: To describe and to correlate the spiritual symptoms presented by the elderly in the municipality of Caldas, Colombia in times of the COVID-19 pandemic.
Materials and Method: Quantitative, descriptive, observational study, with 300 elderly people, a validated instrument on spiritual symptoms was applied, with descriptive statistics using Pearson test.
Results: spirituality symptoms were moderate in terms of spiritual pain with 34%, self-punishment 35%, projected spiritual search was found to be severe in 36% as well as spiritual anguish 42%, disbelief 45%, hopelessness and heartbreak 48%, statistical significance was found correlating spiritual signs with age, sex, occupation, marital status, illness, presence of children and need for help with daily activities.
Conclusions: It is concluded that the results allow describing the spiritual symptoms, as well as making correlations between the symptoms and the various characteristics of the participants. Furthermore, these results allow us to reflect that the care of the elderly must consider, in addition to the biological dimension, the spiritual dimension, showing that care must be taken in a holistic way to improve the health status and quality of life of the elderly Therefore, the problems of the aging process should be considered in its different contexts, and multidisciplinary models and health policies should be proposed that improve the quality and living conditions of this sector of the population and its caregivers.
Key words: Spirituality; Aged; Community health nursing
Cuestionario de reacciones vasovagales a la donación de sangre en una institución de salud
Authors: Mejía Domínguez Ana María , González-Hermosillo Jesús Antonio , Valencia-Cañedo Cesar A. , Hernández-Pacheco Guadalupe
Published: October 2024

Objective: Identify, trough a vasovagal signs and symptoms questionnaire, blood donors in order to record the antecedents that increases the probability of presenting vasovagal reactions.
Materials and Methods: A questionnaire was applied to blood donors, for three months, in the blood bank in a third-level health institution.
Results: 100% of the donors answered negatively to the questions in the questionnaire, but 1.3% of them presented vasovagal reaction, with dizziness, pallor and nausea being the most frequently shown sing and symptoms. When comparing two groups with and without vasovagal reaction matched by sex, age and body mass index, there were no differences between them.
Conclusions: Donors in our country are fundamentally replacement donors, so this circumstance plus their motivations should be considered for the design of surveys aimed at this population.
Keywords: Vasovagal; Blood donors; Replacement
Determinantes de la conducta planeada como predictores del consumo de tabaco y alcohol en adolescentes
Authors: Lopez-Cisneros Manuel Antonio , Alonso Castillo María Magdalena
Published: October 2024

Objective: know the effect of the determinants of planned behavior on tobacco and alcohol consumption in adolescents high schools.
Material and Methods: A predictive correlational descriptive study was carried out with 735 adolescents from High school in the State of Nuevo León, Mexico. A self-administered questionnaire was used, which includes concerning sociodemographic variables, tobacco and alcohol consumption, attitude, subjective norm and perceived behavioral control towards tobacco and alcohol consumption. Logistic regression models were carried out of attitude, subjective norm, perceived behavioral control on tobacco and alcohol consumption.
Results: The subjective norm (OR = 1.02, p = .028) and the perceived behavioral control (OR = 1.084, p = .001) were showed significant for predicting tobacco consumption ever in life. While attitude (OR = .980, p = .017), subjective norm (OR = 1.034, p = .025) and perceived behavioral control (OR = 1.080, p = .001) were showed significant for predicting alcohol consumption ever in life.
Conclusions: With based on the results, it is possible to determine the usefulness and relevance of the theory of planned behavior and the generation of new scientific knowledges that allows the design of programs to face the situations that adolescents perceive as facilitators of tobacco and alcohol consumption.
Keywords: Adolescent; Alcohol drinking; Tobacco consumption; Attitude; Social norms.
Professional Nursing Care: A Framework
Authors: Delmar Charlotte
Published: October 2024

Abstract:The purpose of this article is to present a nursing theoretical framework. Methodologically, the frame of reference is an interaction between philosophical, theoretical reflections, and empirical projects predominantly guided by patient perspectives. The presented framework is divided into three themes: (a) the basic terms of nurse–patient collaboration, where the purpose is to achieve the right distribution of responsibility, and the focus is on how power is actively formed to maintain trust; (b) the professional content of nursing, where the goal is to underline the importance of life phenomena as an addition to human needs; and (c) nursing competencies, where the goal is to develop sensory-focused, situational attention and courage.
Anti-microbial efficacy of garlic (Allium Sativum L.) extract as a root canal irrigant in endodontic treatment
Authors: Cahyani Febriastuti , Farizaldi Reisya Irfanny , Syafaati Lailatul Maghfiroh , Hartanli Audrey Luisa , Aryandhita Amanda Paramitha Putri
Published: October 2024

Background: Herbal medications are an effective alternative in dental endodontic treatment due to their antimicrobial, anti-inflammatory, and biocompatibility properties and thus they are more biocompatible and less cytotoxic. The antibacterial, antifungal, and antiviral properties of garlic (Allium sativum L.) support broad-spectrum activity against gram-positive and gram-negative organisms and effectiveness against multidrug-resistant organisms that are essential as endodontic materials. Purpose: The purpose of this literature review is to analyze how the antimicrobial efficacy of garlic (Allium sativum L.) extract can be used as a root canal irrigant in endodontic treatment. Review: The development of pulp and periapical disease involves high-intensity bacterial activity that proliferates and produces toxic side products such as organic acids. When crushed or minced, garlic releases allicin compounds through the enzymatic action of alliinase (cysteine sulfoxide lyase) on alliin. Allicin, organosulfur compounds, and antioxidant compounds in garlic extract can exert antimicrobial role by inhibiting the synthesis of pathogenic microorganisms, fighting the resulting infection, and working synergistically with other antimicrobial agents to increase the effectiveness of treatment against antibiotic- resistant bacterial infections. In comparison to other antimicrobial agents, a number of studies have shown that there is no significant difference between garlic extract and sodium hypochlorite (NaOCl) in exerting bactericidal effects against pathogenic bacteria. Other studies have also shown that garlic extract has good dentin penetration properties as well as ideal flow and wetting capabilities. Conclusion: Garlic (Allium sativum L.) extract has good antimicrobial efficacy, dentin penetration, as well as ideal properties of root canal irrigation in endodontic treatment
A STUDY OF BLOOD GROUP IN COVID-19 PATIENTS IN TERTIARY CARE HOSPITAL OF AHMEDABAD CITY, GUJARAT, INDIA - AN INSTITUTIONAL STUDY
Authors: Prajapati Arpit Chelabhai , Modi Madhur Yogendra , Patel Mansi Maulik , Sutariya Hardik Jashubhai , Mody Mishal Bhavin
Published: October 2024

Introduction: The associations between ABO system of blood and COVID-19 infection in various studies provide reason to think true associations may be in reality between blood type and incidence of COVID-19 and death due to COVID-19. Objectives:  To estimate frequency of COVID-19 illness in different ABO blood systems and also to find linkage between the ABO system of blood and degree of COVID-19 illness. Methods: A prospective cohort study was conducted on all COVID-19 patients (Patients were grouped A positive and A negative blood groups into 1st group and other blood types such as B, AB, and O, irrespective of their Rh status, into 2nd group) admitted at Tertiary Care Hospital of Ahmedabad City, Gujarat, India during the four months of study duration. Results: COVID-19 infection was found in 380 (63.3%) male. Mean age was 56.46 ±15.35 years in which 26.8% patients were in age group of 60 to 70 years. Among total 600 patients, 35% of patients were having B positive type of blood followed by O positive type of blood (25%). There were 25% of patients having overall co-morbidity like diabetes. And 8% of B positive patient having co-morbidity and amongst the, 1.2% patients were admitted to Intensive Care Unit. Case fatality rate was 7.5%. Among B positive blood group patients, 37.8% deaths occurred. Conclusion: Patients having blood group O may have lower chances of ICU admission as compared to other blood groups.
THE INVOLVEMENT OF DIFFERENT VITAMIN TYPES IN ASSISTING THE ACTIVATION OF STEM CELLS: A REVIEW
Authors: Prima Hapsari Tyastuti
Published: October 2024

Recent research indicates that vitamins play a key role in regulating cellular processes, especially in stem cells. Stem cells are undifferentiated cells with the potential to develop into various cell types and regenerate themselves. The article selection process followed predetermined inclusion criteria and spanned from March 18, 2024, to March 31, 2024, lasting one month. Articles were searched using specific keywords, and those meeting the criteria were selected. Six articles were collected for review, primarily focusing on assessing the role of each vitamin in stem cell survival. Most vitamins studied have shown similar functions in enhancing the viability of stem cells by promoting their differentiation. However, recent research has revealed a unique role for vitamin E in relation to stem cells. Vitamin E acts as a facilitator for mesenchymal stem cells, inhibiting dendritic cells and enhancing their immunomodulatory effects. All these vitamins are pivotal in preserving the wellbeing and functionality of both stem cells and bodily tissues.
THE INFLUENCE OF MARKERS IN THE DIFFERENTIATION PROCESS OF STEM CELLS INTO ENDOTHELIAL CELLS TO SUPPORT TREATMENT TESTING EXPERIMENTS
Authors: Nurdiyati Nanis
Published: October 2024

Research on stem cells, particularly their differentiation into endothelial cells, is highly significant in the field of biomedical science and regenerative therapy. Endothelial cells are crucial for blood vessel formation, wound healing, tissue regeneration, and the treatment of degenerative diseases. Human pluripotent stem cells can differentiate into various cell types, making them valuable for repairing or replacing damaged tissue. This study reviews the role of markers in distinguishing human stem cells into endothelial cells. A comprehensive literature search was conducted, and out of 428 screened articles, only 4 met the inclusion criteria. SOXF proteins were analyzed using scRNA-seq analysis, focusing on their role in enhancing stem cell differentiation. SOX17 was found to significantly increase the percentage of cells expressing CD34+ and Vascular Endothelial Cadherin (VEC), consistent with its known role in endoderm differentiation and endothelial cell specification. SOX17 can override pluripotency signals in human stem cells, triggering their differentiation into endothelial cells. Overexpression of SOX17 in human stem cells resulted in cells with endothelial characteristics, and combining SOX17 with FGF2 enhanced this effect, resulting in more than 90% of cells expressing endothelial stem cell markers (CD34+, VEC+, CD31+). SOXF was applied to prompt stem cell differentiation, with only SOX17 demonstrating notable effectiveness.
Recent advances in preparation, thermoelectric properties, and applications of organic small molecule/SWCNT composites
Authors: Liu Peiyao , Li Yiyang , Ni Zhenjie , Guo Cun-Yue
Published: October 2024

Thermoelectric materials allow for direct conversion between heat and electricity, realizing a facile and effective utilization of waste heat and thermal management. Semiconductive organic small molecules (OSMs) have attracted ever-increasing attention in thermoelectric device fabrication due to their simplicity in synthesis, well-defined molecular structure, low toxicity, and low thermal conductivity (κ ). As a unique one-dimensional (1D) carbon allotrope, single-walled carbon nanotubes (SWCNTs) have excellent structural and electrical properties. Thermoelectric OSM/SWCNT composites with both high conductivity and low thermal conductivity have drawn great attention among researchers and achieved remarkable progress. However, current research fails to give a clear relationship between the structure of small molecules and their thermoelectric performance, and the microscopic mechanisms governing the formation of OSM/SWCNT composites are not well understood as well. These, in all, need further investigation to guide future development in preparing high-performance OSM/SWCNT thermoelectric composites. In this review, we introduce recent advancements in thermoelectric OSM/SWCNT composites, providing a detailed overview of optimization strategies for small molecule dopants. Also summarized in this review article is the design of OSMs from various aspects, including energy level regulation, side chain modification, selection of substituents, etc. Different preparation methods and applications of OSM/SWCNT composites are introduced in detail. Finally, outlooks on the future development of OSM/SWCNT composite thermoelectric materials are pointed out.
SPIRITUAL OR MENTAL: CRIMINAL LEGAL DISCOURSE
Authors: Myslyvyy V. , Stadnik S.
Published: October 2024

The article examines the criminal-law categories "soul" and "mental," which characterize the features of the subjective side in the criminal law of Ukraine, as both lawful and unlawful activities of a person within its norms are inextricably linked with their mental qualities. It is noted that these categories are important for the criminal-law assessment of circumstances that exclude criminal unlawfulness of the act, as well as for analyzing the features of the subjective side of certain crimes against health and life, their qualification, consideration as circumstances mitigating and aggravating punishment, and also its imposition. The genesis of the concept "soul" in criminal law, its established nature, and its relationship with the term "mental," as well as the pervasive application of these categories in current criminal legislation, are examined. It is emphasized that such features of the subjective side of a criminal offense as sanity, diminished sanity, insanity, guilt, motive, purpose, and others are inherently based on the key concept of "mental," and are also defined through the term "intense emotional disturbance." At the same time, the term "soul" serves as a central factor in the latter. Based on the analysis of criminal-law theory, legislation, and judicial practice, it is confirmed that the use of the term "intense emotional disturbance" in criminal law is inappropriate since it does not correspond to the level of modern psychological science. It is concluded that it is impossible to replace the concept of "intense emotional disturbance" with such terms as physiological or cumulative affect, frustration, and others. Based on the results of the research regarding the criminal-law discourse of the categories "soul" and "mental," a conclusion is made in favor of the latter, on the basis of which it is proposed to replace the phrase "intense emotional disturbance" in the Criminal Code of Ukraine with the legislative construction "extraordinary mental state" of a person.
Exploring El Nino effects on agricultural area using Landsat images analysis: A case study in Bondowoso Regency, Indonesia
Authors: Suud Hasbi Mubarak , Kusbianto Dwi Erwin
Published: October 2024

El Nino, which hit Indonesia in 2023, poses severe food security threats due to the high dry season with no rainfall and minimal cloud cover and can trigger serious drought problems if it happen for a long time. This study aimed to explore the impact on agricultural land in Bondowoso Regency during El Nino events. The analysis in this study primarily uses land surface temperature (LST) and normalized difference vegetative index (NDVI) map distribution. The Landsat data from USGS are collected and processed to become LST and NDVI distribution maps. Data analysis focused on the agricultural area layers based on data from the Indonesia geospatial portal. Referring to the LST and NDVI map distribution, the notable rise of LST starts in August 2023, and the peak is in October 2023. Around 46% of areas in the Bondowoso regency are detected as hotspot areas, which had LST above 30oC in October 2023. El Nino affects the irrigated lands and rain-fed fields more than the plantations. The NDVI alteration data does not show that the Bondowoso Regency is experiencing extraordinary drought due to the short-term impact of El Nino. However, the emergence of numerous areas in the moderate NDVI category warns that stress affecting vegetation is starting to occur. Mitigation plans should be prepared for the long-term impact of El Nino, particularly in the hotspot areas. This study could be a comprehension tool for the government and farmers to prepare mitigation plans.
Unilateral Biportal Endoscopic Discectomy for Adjacent Segment C7-D1 Disk with O-Arm Navigation
Authors: Hadgaonkar Shailesh , Balvantrao Patil Bhushan , Sancheti Parag K.
Published: October 2024

Case:

43-year-old man with an adjacent segment C7-D1 left paracentral and foraminal disk and left-hand grip weakness underwent unilateral biportal endoscopic discectomy with O-arm navigation. The patient underwent C5-6 and C6-7 anterior cervical discectomy and fusion (ACDF) 10 years ago and was asymptomatic for nearly 10 years.

Conclusion:

In revision of the cervical spine with a short neck, cervicothoracic junctional disks can be precisely located using O-arm navigation and effectively removed with a minimally invasive unilateral biportal endoscopy approach.