bluuebunny/crossref_metadata_2025 huggingface dataset:
GOOGLE WORKSPACE EM INSTITUIÇÕES ACADÊMICAS DA SAÚDE: PERFIL DE UTILIZAÇÃO
Authors: Ferreira Alexandre Alves , Rondina João Marcelo
Published: November 2024

Introduction: The study investigates the use of Google Workspace in an academic health institution, highlighting the role of digital technologies in supporting remote teaching during the COVID-19 pandemic. Tools such as Google Classroom, Meet and Drive were essential for the continuity of learning. Methodology: The descriptive quantitative research analyzed Google Workspace usage data between 2021 and 2023. With a sample of 250 participants, including teachers and students, the data was anonymized and processed with Python to identify usage patterns, categorized by device type and geographic location. Results and Discussion: The results showed that 55.4% of the documents on Google Drive were shared, evidencing a collaborative culture. Google Meet excelled in synchronous classes, especially on mobile devices, with longer meetings on computers, suggesting stability and comfort in extended sessions. Documents in Google Docs format and PDFs were the most used, reflecting the accessibility of native formats. The activities were concentrated on weekdays, with peaks of use on Mondays. This data reveals that while technology provides important support for remote learning, its effective use requires ongoing training and support. Conclusion: The study demonstrates the positive impact of Google Workspace on health education, but emphasizes that the effectiveness of the technology depends on well-planned integration and regular training. Digital technology complements teaching, but does not replace the need for hybrid and flexible pedagogical methods, which integrate face-to-face and remote learning, facilitating interaction and accessibility in higher education
MANAGEMENT OF ANTICOAGULATION IN ATRIAL FIBRILLATION: MINIMIZING DRUG INTERACTIONS WITH DOACS
Authors: Da Silva Sarah Camila Santos , Lee Marcelo Simonelli , Dell'Antonia Victor Tadeu , Martiniano Felipe Santos Teixeira , da Luz Elton Ramos , Fiore Sérgio Augusto Peres , Morais Pietro Conrado Carneiro Quadros , Veraldi Priscylla Silva
Published: November 2024

Introduction: Atrial fibrillation (AF) is a common cardiac arrhythmia that elevates the risk of thromboembolic events, necessitating effective anticoagulation strategies. Direct oral anticoagulants (DOACs) have become the preferred choice due to their safety profiles; however, drug interactions can compromise their efficacy and safety. Objective: This study aims to assess the impact of drug interactions on the efficacy and safety of DOACs in patients with AF. Method: A literature review was conducted using databases such as the Virtual Health Library, LILACS Plus, and Medline, focusing on articles published from 2019 to 2024. Inclusion criteria emphasized studies related to drug interactions involving DOACs and AF, resulting in the selection of 13 relevant articles. Results: The analysis revealed a significant prevalence of drug interactions among patients treated with DOACs. Co-prescription with CYP3A4 inhibitors and P-glycoprotein modulators was linked to increased bleeding risks. Factors such as age, renal function, and the presence of comorbidities were crucial in determining appropriate dosing and the risk of adverse events. Conclusion: Careful management of AF patients on DOACs is vital to mitigate risks associated with drug interactions. Personalized treatment approaches that consider individual clinical profiles and ongoing education for healthcare providers are essential to optimize anticoagulation therapy.
INFÂNCIA E ALIENAÇÃO PARENTAL: UMA INTERFACE ENTRE ORDENAMENTO JURÍDICO E PSICOLOGIA
Authors: Santos Francisca Nayane de Sousa , Da Cruz Ronald Taveira
Published: November 2024

The present work investigates parental alienation, focusing on legal and psychological aspects related to the social phenomenon in question. It sought to verify the modes of prevention and repression used by the State to contain this practice, as well as the possible consequences and influences on child development and the establishment of parental relationships. It was investigated how the covid-19 pandemic reflected in cases of parental alienation.  Recent data from the Superior Court of Justice of Piauí were broadcast by the Bom Dia Piauí program, pointing out that the number of cases of parental alienation doubled in the state during the period of social isolation, jumping from 10 cases in 2019 to 23 cases in 2020. In this sense, shared custody was explored in the research as a way to inhibit this practice. For the contextualization and analysis, a bibliographic and legislative research was carried out, and the use of theoretical references was allowed through the exploration of data contained in books, articles, scientific works, legislation and websites.
EDUCATIONAL EXPERIENCES AND ASSISTIVE TECHNOLOGY: CONTRIBUTIONS TO THE SCHOOLING OF THE BLIND
Authors: Eich Milena Schneid , Valentini Carla Beatris
Published: November 2024

Inclusive Education requires attention to learning and coexistence to provide spaces for everyone to play a leading role. We need to go beyond obstacles and look at the potential of people with disabilities. This article proposes a reflection on people with visual impairments, considering the processes that segregate and exclude them, as well as their potential and experiences of inclusion. To this end, narrative interviews were carried out to access the educational experiences of four adults with visual impairments. The interviews were analyzed using Bardin's Content Analysis (2011), with the support of the software Atlas TI, and were asked how the educational trajectories and experiences with Assistive Technology contributed to the interviewees' schooling process. The results show that the time the participants spent in educational institutions was segregating and excluding, but that there were also possibilities for developing potential and learning in inclusive and emancipatory contexts. Assistive Technology resources appeared throughout the participants' school lives in different ways and for different reasons, acting as mediators in the learning process.
IMPACT OF COVID-19 CASES ON ONLINE SEARCHES FOR COGNITIVE SYMPTOMS AND PERSISTENT COVID-19 SYMPTOMS IN BRAZIL
Authors: Da Silva Kelly , Santos Nathália Monteiro , Martins-Filho Paulo Ricardo , Santos Franciely Oliveira de Andrade , Souza Franklim Oliveira , Dos Santos Ronaide Paula , Guedes-Granzotti Raphaela Barroso , Dos Santos Priscila Lima
Published: November 2024

Objetive: This study aims to investigate the impact of COVID-19 case numbers on online searches for persistent cognitive symptoms in Brazil. Material and Methods: Utilizing Google Trends™ as a proxy, we analyzed the relative normalized search volume numbers for "memory loss," "forgetfulness," and "persistent COVID-19" from March 2020 to November 2023. Result: Pearson correlation analysis was employed to explore the relationship between search volumes and registered COVID-19 cases per epidemiological week. The study revealed variable search patterns for cognitive symptoms, with "forgetfulness" showing significantly higher search volumes than "memory loss" and "persistent COVID-19." Conclusion: A weak to moderate significant correlation was found between search volumes for cognitive symptoms and the number of COVID-19 cases, particularly in the first two weeks following diagnosis. This indicates an immediate public response to COVID-19 infections with increased online information-seeking behavior regarding cognitive issues. Our findings underscore the significance of infodemiology and infoveillance in monitoring public health concerns, especially during pandemics.
ATUAÇÃO DO ENFERMEIRO PERANTE FERIDAS OPERATÓRIAS EM MASTOPEXIA COM PRÓTESE E ABDOMINOPLASTIA EM CIRURGIA PLÁSTICA
Authors: Lins Andreza Moreira Ribeiro , Alves Ednaly Francelino de Pontes , Schibler Carlos Eduardo Michel , Oliveira Giovanna , Barboza Maria Julia Turra , Pereira Rafael Gonçalves , Rodrigues Rodrigo Gomes , Dos Santos Vitor Adão
Published: November 2024

Introduction: Surgical wound infection is a most common adverse event in the healthcare area and results from the surgical site itself. Nurses play an important role in this intervention, whose objective is to treat the cause and promote healing, using their technical-scientific knowledge and systemic view of the patient. Objective: To investigate the knowledge and techniques that best support nurses, in their practice, for the process of evaluation and treatment of surgical wounds. Methodology: Integrative literature review with a qualitative approach. Results and Discussion: Through the selection of studies, it was possible to verify the importance of the knowledge and techniques used by nurses in the wound treatment process. Conclusion: The studies pointed out not only the importance of the nurse's role but also the need for technical-scientific knowledge to guide the best therapy
CORRUPÇÃO NAS DECISÕES DO PODER JUDICIÁRIO: UMA ANÁLISE PARA O BRASIL
Authors: Lima João Rafael Cavalcante de Andrade , Henrique Angelica da Trindade
Published: November 2024

Este estudo analisa as consequências da corrupção nas decisões judiciais no Brasil, com foco no período pós-redemocratização. A corrupção, um fenômeno enraizado na história brasileira, tem corroído a confiança pública nas instituições, afetando principalmente o Poder Judiciário, que deveria ser o guardião da justiça e da imparcialidade. O trabalho busca identificar os fatores que contribuem para a corrupção no Judiciário e examinar suas implicações na percepção pública da legitimidade e imparcialidade das decisões judiciais, tendo como problema de pesquisa a seguinte questão: como a corrupção afeta a percepção da sociedade no que se refere a imparcialidade do judiciário brasileiro após a redemocratização? A hipótese do trabalho é que a insegurança jurídica aumenta na medida em que também se eleva a percepção de corrupção no Judiciário por parte da sociedade, impactando a confiança nas decisões judiciais. O estudo é de natureza qualitativa, baseada em uma análise bibliográfica de estudos publicados entre 2020 e 2024. Os resultados apontam que a corrupção no Judiciário gera insegurança jurídica, impacta a confiança da população no sistema legal e contribui para a sensação de impunidade. Além disso, a pesquisa revela que a percepção de corrupção entre a população aumenta a desconfiança nas decisões judiciais.
ANALYSIS OF THE LACK OF IMPLEMENTATION OF THE COST SYSTEM IN A PUBLIC HIGHER EDUCATION INSTITUTION
Authors: Dantas Luiz Antonio de Oliveira , Forte Denis , Kadri Nadia Wagih El
Published: November 2024

This article aims to analyze the impacts of the non-implementation of an efficient cost system in a Brazilian public higher education institution (HEI) and to propose recovery strategies based on the Spanish Costing Model (ECM).

Methodology: The research follows a qualitative approach, using descriptive and exploratory methods. Data collection included document analysis, semi-structured interviews with managers and employees, and participant observation of the administrative and financial processes of the HEI.

Gap: Despite the detailed recommendations and benefits projected by the study "Cost-per-student analysis as a tool for managerial decision in a public higher education institution" by Luiz Antonio de Oliveira Dantas (2022), the Brazilian public HEI analyzed, which did not authorize the disclosure of its name, did not adopt these practices, resulting in ineffective management and deterioration of the quality of services.

Results and Contributions: The analysis revealed that the absence of an efficient cost system led to financial uncontrollability, operational inefficiency, a drop in the quality of services, and a lack of transparency. The late implementation of the MCE proved effective in reversing these problems, improving resource allocation, operational efficiency, and quality of services. This study contributes to the academic literature by demonstrating the importance of standardized cost systems for the sustainability of public HEIs.

Relevance: This study reinforces the critical importance of cost-efficient systems for financial management and service quality in public HEIs, offering valuable insights for managers and policymakers.

Impact: The experience of the HEI studied serves as a guide for other institutions facing similar challenges, highlighting the need for continuous capacity building and adoption of efficient cost management practices to ensure financial sustainability and transparency.
CEPAS NATIVAS DE Trichoderma PARA EL CONTROL DEL MOHO GRIS (Botrytis cinerea Pers.) EN FRUTOS Y FLORES DE ARÁNDANO (Vaccinium corymbosum L.)
Authors: Arestegui Cantoral Yasmin Carmen , Gaslac Zumaeta Eryka , Leon Ttacca Betsabe
Published: November 2024

Background. Gray mold disease caused by Botrytis cinerea Pers. is a phytosanitary problem in blueberry (Vaccinium corymbosum L.). It is characterized for affecting soft tissues (flowers and fruits) in the field and in the post-harvest stage, reducing crop yield. This has motivated to the search for native strains of Trichoderma that are effective in biological control. Objective. To determine the effect of 19 native Trichoderma strains on the control of gray mold on flowers and fruits of blueberry under laboratory conditions. Methodology. Under a complete randomized experimental design, mycoparasitism and antibiosis tests were carried out to evaluate colonization and mycelial inhibition of the pathogen, respectively, using the dual confrontation method and production of secondary metabolites. For the bioassays, a suspension of 1×106 conidia mL-1 per strain was sprayed on blueberry flowers and fruits. Disease incidence and severity were evaluated. Data were analyzed with the statistical program InfoStat. Results. All Trichoderma strains completely colonized the pathogen, being considered as aggressive mycoparasites and inhibited the mycelial growth of the pathogen up to 42.74%. Likewise, the application of Trichoderma spore suspension had inhibitory effects on gray mold, highlighting the strain HE- ArT161 that reduced the incidence (66.67% and 20%) and severity (34% and 12%), respectively in flowers and fruits. Implications. The use of these native strains of Trichoderma may contribute to future research in the field where they can be incorporated for an integrated management of the disease. Conclusion. These Trichoderma isolates against B. cinerea showed in vitro control, stimulating mycelial inhibition of the pathogen and reducing the development of disease lesions.
POLÍTICA PÚBLICA PROGRAMA RESIDÊNCIA PEDAGÓGICA E A PORTARIA Nº 82/2022
Authors: Ribeiro João Pedro da Rosa , Pinto Muriel , Colvero Ronaldo Bernardino
Published: November 2024

O Programa Residência Pedagógica é uma política pública educacional brasileira. A mesma tem o intuito de fomentar as práticas pedagógicas de alunos de licenciatura de instituições de ensino superior públicas e privadas. Já houveram 3 edições, da policy em estudo. Esta pesquisa visou conhecer a realidade do Programa Residência Pedagógica – Núcleo Geografia da Universidade Federal do Pampa. O programa em questão está ancorado e regula-se a partir da Portaria Nº 82/2022. Em específico, buscou-se saber se os atores reconhecem suas atribuições baseadas nesta normativa. Foram acessadas respostas de 3 dos 4 atores que compõem o programa, ou seja, Coordenador Institucional, Docente Orientador e Preceptor. Ao todo, foram coletados dados de 1 Coordenador Institucional, 2 Docentes Orientadores e 4 Preceptores. Assim, para recolher as informações citadas, fez-se uso de questionário. Para compor a interpretação, usou-se a análise de conteúdo. Entre os resultados obtidos, estão o conhecimento integral da normativa por parte de um dos Docentes Orientadores e parcialmente por parte do outro. Já sobre os Preceptores, dois identificam de modo integral suas atribuições, um de modo parcial e outro apenas um de seus deveres. Por parte da Coordenação Institucional, a mesma disse conhecer todos os seus deveres e ressaltou a importância de conhecer a normativa para o desenvolvimento seu trabalho.
Resilience and Management Control Systems in Agribusiness Companies: A Case Study of PT Pandu Karya Aksara
Authors: J. C. Wangke Shinta , Mandagie Yunita , M. Gunawan Emilia
Published: November 2024

Despite the abundance of research focused on firm resilience, there are still very few studies that analyze internal mechanisms to see what generates resilience capacity in agribusiness firms. Considering the Management Control System (SPM) as a driver of organizational change, this study aims to analyze the role of SPM as a determinant of resilience in agribusiness companies with a case study on PT Pandu Karya Aksara. This study uses a qualitative method with a case study approach. The data collected consisted of primary data and secondary data. Primary data was obtained from semi-structured interviews, while secondary data was obtained from observation and analysis of documents. This research provides benefits for the development of science and insights in supporting adaptive behavior and assisting effective decision-making, so that companies can improve competitiveness and efficiency.  This research shows how resilience is generated and strengthened through SPM, when companies are faced with various challenges, such as fluctuations in commodity prices, climate change, market uncertainty, and regulatory changes.
Survey of Public Needs on The Design of an Integrated Information System Model for Adolescent, Mother, and Child Health
Authors: Kostania Gita , Cahyani Desy Dwi , Rosmalawati Ni Wayan Dwi
Published: November 2024

Maternal Mortality Rate (MMR) and Infant Mortality Rate (IMR) in Indonesia are still high, with MMR reaching 305/100,000 live births and IMR at 22.23 per 1,000 live births. Although the government has launched various programs for adolescent, maternal, and child health, there has been no effort to integrate these programs into a comprehensive reproductive health cycle. This study aims to analyze the needs of the community in designing an integrated information system model for adolescent, maternal, and child health. This study used a survey design conducted in Dau, Malang Regency, Indonesia. The population consisted of all women of childbearing age (15-49 years) totaling 945 people, with a sample size of 311 respondents obtained using the Slovin formula. The sampling technique used cluster sampling from 4 RW in Petungsewu Village, and 279 respondents could be processed. The research instrument used a questionnaire, and the data were analyzed quantitatively in the form of frequency distribution. The results of the data analysis showed that the design of the integrated model of adolescent, maternal, and child health has significant potential as the basis for developing an integrated website system. This system not only facilitates comprehensive health education but also strengthens real-time health recording and reporting mechanisms. This study shows that the integration of health education is essential to meet the different information needs of adolescents, mothers, and children. The model successfully identified and categorized these needs, so that the developed website could provide relevant and specific content for each user group.
Bea Office Authority And Taxes In Obtaining Access To Financial Information For Customs Value Determination
Authors: Chotibul Umam  , Ismail  , Chandra Mardi
Published: November 2024

In import activities, importers will submit an Import Declaration of Goods for the imported items based on the documents they possess. They will self-assess the customs tariff and value for calculating the customs duties, as well as calculate and pay the applicable charges, including customs duties, value-added tax, luxury goods tax, and income tax. The Customs and Excise Officer will determine the customs value based on the Import Declaration of Goods submitted by the importer, as stipulated by the Customs Law. On one hand, importers may potentially declare a lower customs value to reduce the charges, while on the other hand, the Customs and Excise Officer may be skeptical and potentially set a higher customs value. The condition can lead to potential unfairness and discrepancies in the determination of customs value. In this thesis, the author uses two theories, namely Plato's theory of justice and Philipus M. Hadjon's theory of authority, to analyze the problem formulation of how the determination of customs value is implemented and how to make it more accurate and objective. The research method used in this study is normative juridical research. The author utilizes secondary data consisting of primary legal materials, secondary legal materials, and tertiary legal materials. Data collection techniques involve the use of documents and library materials for secondary legal data. The legal material analysis used in this research is interpretation, employing juridical methods to discuss legal issues. The research findings indicate that the determination of customs value carried out by the Customs and Excise Officer is regulated by legislation and implemented according to applicable provisions. However, there is a lack of authority to access financial information possessed by the Customs and Excise Officer. This lack of authority has the potential to result in unfair customs valuations and abuse of power. Such conditions can lead to unfair competition and legal uncertainty. Therefore, it is necessary to provide access to financial information for customs officers in the determination of customs value, so that the customs value, which represents the transaction value between importers and exporters, can be accurately determined and encourage a more accurate and objective customs valuation.
Law Enforcement Against Perpetrators of Terrorism Crimes to Realize Legal Certainty
Authors: Woso Yunisman Yansen , Chandra Tofik Yanuar , Mau Hedwig Adianto
Published: November 2024

Terrorism crime is a form of crime with an international dimension that is very frightening to the public. In various countries in the world, terrorism crimes have occurred both in developed and developing countries, and acts of terror have taken victims indiscriminately. The formulation of the problem raised is: How can law enforcement against perpetrators of terroristic crimes in Indonesia be regulated? And how is law enforcement against perpetrators of terrorism crimes in Indonesia to realize legal certainty? The research method used is normative juridical with a case, legislation, and concept research approach. The legal materials used are primary, secondary, and tertiary, while the analysis of qualitative legal materials is qualitative. The results of the study show that terrorism is a complex series of actions, so basically, efforts to prevent and eradicate terrorism crimes will not be adequate if only carried out in one law. The existence of laws and regulations related to terrorism is directed to answer public anxiety over acts of terror that occur, but until now, terrorism crimes continue to occur. So, an ideal concept is needed, in this case, the involvement of all components of society by being outlined in laws and regulations in the context of preventing and overcoming terrorism. This concept is a more effective means of preventing and eradicating terrorism crimes in addition to criminal law. Therefore, making community leaders effective and educating and directed in the prevention and eradication of terrorism is a concrete step in eradicating terrorism.
Liability of Consumers Against Producers Through E-Commerce Against Sellers with a Cash on Delivery Transaction System
Authors: Sulasno  , Razani Nurma Arafah
Published: November 2024

The dynamics of competition in the business world are now increasingly advanced and up-to-date. There are developments in the science of digital information technology around the world, with the utilization of the Internet as a medium of communication. Commerce more and more rely on electronic electronic commerce (E-Commerce) for transaction media facilities. The transaction method is made easy and provides various forms of payment such as credit card/visa, bank transfer, visa debit, joint account, pay later, e-wallet, cash at retail outlets, and cash on delivery. The number of e-commerce users who use cash on delivery causes legal problems to arise. This research uses a qualitative method with an empirical juridical research approach. Empirical juridical research, which can also be called field research, examines the applicable legal provisions and examines what examines the applicable legal provisions and what happens in reality in the community. in the community. Data collection techniques were conducted by researchers using observation, interviews and documentation. Based on the results of the research it shows that if there is negligence caused by the E-Commerce producer, which causes losses where the goods received are not in accordance with what has been promised, then the fulfillment of the elements of default as stipulated in Article 1243 KUHPerdata and the producer has the right to be responsible to consumers who are harmed. who is harmed? Forms of producer responsibility include costs or new goods according to the initial agreement of the e-commerce platform, as well as dispute resolution, which can be done by litigation or non-litigation.
Non-compliance of State Administrative Officials with State Administrative Court Decisions that have Permanent Legal Force (Case Study of Bandung PTUN Decision Number: 06/G/2006/PTUN-BDG)
Authors: Hardiyanto
Published: November 2024

One of the implementations of the concept of the civil law state is the existence of an administrative judicial institution, namely the state administrative court. As the executor of judicial power, the state administrative court has the authority to issue decisions that are declarative, constitutive, and condemnatory. However, until now, the imposition of administrative sanctions still faces juridical challenges due to the voluntary mechanism for imposing administrative sanctions. The author of this study uses normative legal research methods.  From this study, it is known that the factors that cause non-compliance of state administrative officials with state administrative court decisions are: (1). There is no special executive institution or sanctioning institution that functions to implement the decision; (2). There is a low level of awareness among TUN officials about obeying the TUN court decision; (3). There is no firmer regulation regarding the implementation of the PTUN decision.
Metformin Attenuates Hepatic Fibrosis in Mice by Altering the Gut Microbiota
Authors: Huang Xiuxin , Peng Chunxiu , Ye Zhijian , Wei Ke , Zhang Zhiyong
Published: November 2024

Background: Metformin is a first-line drug widely used in the treatment of type 2 diabetes. It has been shown to improve liver fibrosis; however, the underlying mechanism remains unclear. Objectives: This study investigates the relationship between metformin and gut microbiota in the treatment of liver fibrosis. Methods: Carbon tetrachloride (CCl₄) was injected intraperitoneally to induce liver fibrosis in mice, followed by metformin treatment for 4 weeks. A CCl₄-induced hepatic fibrosis mouse model was established. The mice were divided into two groups: Metformin treatment and control groups. Hematoxylin-eosin (HE) staining was used to evaluate the overall liver condition, Sirius red staining to assess the degree of hepatic fibrosis, α-smooth muscle actin (α-SMA) immunohistochemical staining to determine the activation of hepatic stellate cells (HSCs), oil red O staining to observe intracellular lipid droplets in hepatocytes, and 16sRNA sequencing to analyze fecal microbiota. Results: In the untreated CCl₄-induced hepatic fibrosis model, hepatic tissue exhibited edema, degeneration, intracellular lipid deposition in hepatocytes, and inflammatory cell infiltration between lobules. Metformin treatment attenuated hepatic fibrosis (area reduced from 1.383% to 0.669%, P < 0.001), decreased inflammatory cell infiltration, reduced intracellular lipid accumulation in hepatocytes (area reduced from 0.457% to 0.086%, P < 0.001), and decreased α-SMA protein expression (area reduced from 1.509% to 0.598%, P < 0.05). Additionally, metformin reduced harmful bacteria and increased the abundance of beneficial bacteria in the intestinal tract of the mice. Conclusions: These findings indicate that metformin reduces liver inflammation, alleviates liver fibrosis, and alters the intestinal microbiota. The modification of gut flora may be a significant mechanism by which metformin exerts its therapeutic effects on liver fibrosis.
Dexmedetomidine Nasal Packing Versus Intravenous Dexmedetomidine for Controlling Bleeding During Turbinate Surgeries: A Randomized Double-Blind Trial
Authors: Abdelsalam Wafaa Mohamed , Hassan Adel Ali , Ghoniem Basma M. , Elsharkawy Mahmoud Fawzy , Shams Gamal Hendawy
Published: November 2024

Background: Nasal obstruction due to hypertrophied turbinates (HT) is one of the common reasons for patients undergoing turbinate operations. This condition is associated with intraoperative nasal bleeding, which can obscure visibility of the field and prolong surgery time. Objectives: The purpose of this study is to compare dexmedetomidine-soaked nasal packing (NP) and intravenous (IV) dexmedetomidine (DEX) for managing bleeding during turbinate surgeries to reduce blood loss and improve surgical field quality. Methods: This randomized, double-blind trial was conducted on 60 patients aged between 18 and 65 years undergoing turbinate surgeries. Patients were randomly assigned into two equal groups: Group NP received DEX-soaked NP (1.5 µg/kg for 10 minutes) and an IV saline bolus followed by saline infusion. Group IV received a 0.5 µg/kg DEX bolus over 10 minutes, followed by a 0.1 - 0.4 µg/kg per hour IV infusion and saline-soaked NP. Results: The mean intraoperative blood loss was 124.1 ± 34.85 mL in group NP and 115.63 ± 31.89 mL in group IV, with no significant difference. Intraoperative hemodynamics, surgical field quality scores, time to first rescue analgesia, total postoperative pethidine consumption, pain score, patient satisfaction, and side effects were comparable. Conclusions: Dexmedetomidine NP is non-inferior to IV DEX for controlling intraoperative bleeding during turbinate surgery. Both methods provided comparable surgical field quality, patient satisfaction, and pain management outcomes.
Antiproliferative and Anticancer Activity of Chrysin on Human A549 Lung Cancer Cell Lines; Possible Clinical Application
Authors: Asghari Armin , Firouziamandi Akram , Dadashpour Mehdi
Published: November 2024

: The current study aimed to assess the anticancer properties of Chrysin (Chr) as a potential therapeutic option for cancer. For this purpose, we analyzed both its toxic effects on the cells and the levels of genes related to apoptosis following treatment with Chr. The effect of Chr on cell proliferation and the expression levels of apoptosis-related genes in the A549 lung cell line was evaluated using the MTT assay and qPCR, respectively. The findings from the cytotoxicity test revealed that the IC50 of Chr for A549 lung cancer cells was 20 μM. This result indicates that Chr exhibits significant cytotoxic effects at this concentration, underscoring its potential as a powerful anticancer agent. Furthermore, the real-time PCR analysis showed significant changes in gene expression after treatment with Chr. Specifically, Chr was found to decrease the expression of human telomerase reverse transcriptase (hTERT) and Bcl2, both associated with cell growth and survival. Conversely, Chr increased the expression of Bax, a gene that promotes apoptosis. These molecular changes suggest that Chr may induce apoptosis in A549 lung cancer cells by altering the balance between anti-apoptotic and pro-apoptotic factors. In conclusion, the findings from this study indicate that Chr effectively inhibits the growth of A549 lung cancer cells through its cytotoxic properties and the regulation of apoptosis-related gene expression. This property positions Chr as a promising candidate for further investigation and development in cancer treatment strategies, and additional studies are necessary to understand its mechanisms of action and potential therapeutic benefits.
The Effect of Vitamin D Cream on the Severity of Pregnancy Striae in the Thigh Region of First-Time Pregnant Women: A Triple Blind Randomized Clinical Trial
Authors: Taheri Hadis , Kheirkhah Masoomeh , Ghobadi Ali , Eshraghi Nooshin , Haghani Shima
Published: November 2024

Background: Pregnancy striae, or stretch marks, are highly prevalent and often a source of cosmetic concern for many women, presenting challenges in both prevention and treatment. Objectives: This study aimed to evaluate the effect of vitamin D cream on pregnancy striae in the thigh area of first-time pregnant women. Methods: This triple-blind randomized clinical trial involved 60 primigravida women, aged 18 - 20 weeks, referred to Shahid Akbarabadi Hospital in Tehran, Iran, in 2022. Using blocked randomization, participants were assigned to two groups: The vitamin D cream intervention group (30 women) and the basic cream placebo group (30 women). Each cream was applied daily for 4 months, twice daily with a 12-hour interval. The severity of striae was assessed using the Atwal Scale before the intervention and at 4, 8, 12, and 16 weeks after the intervention commenced. Data analysis included descriptive statistics (frequency, minimum, maximum, mean, and standard deviation) and inferential statistics (chi-square, Fisher’s exact test, independent t-test, and Mann-Whitney test). Results: At the fourth, eighth, twelfth, and sixteenth weeks, the incidence of striae was as follows: Vitamin D group: 96.2%, 92.3%, 92.3%, and 88.5% without striae and 3.8%, 7.7%, 7.7%, and 11.5% with moderate erythema, respectively. Placebo group: 83.33%, 83.33%, 83.33%, and 66.67% without striae and 16.67%, 16.67%, 16.67%, and 33.33% with moderate erythema, respectively. No significant difference was found between the two groups regarding the severity of pregnancy striae at all follow-up times. Conclusions: Over the 4-month follow-up period, vitamin D cream did not demonstrate greater effectiveness than placebo in preventing or reducing the severity of pregnancy striae in the thigh area.
Care Needs of Patients with Chronic Cardiovascular Diseases from the Perspective of Nurses: A Qualitative Study
Authors: Nabi Foodani Mahdi , Abbasi Dolatabadi Zahra , Ghiyasvandian Shahrzad , Zakerimoghadam Masoumeh
Published: November 2024

Background: Chronic cardiovascular diseases (CVDs) are a leading cause of death globally, making it essential to understand the comprehensive care needs of individuals living with these conditions. Nurses who also suffer from chronic CVDs offer a unique dual perspective, combining professional expertise with personal experience. Objectives: This study aims to explore the care needs of patients with chronic CVDs from the perspective of nurses who themselves live with the condition. Methods: A qualitative content analysis was conducted, with interviews carried out between November 2023 and March 2024, involving 23 nurses affected by chronic cardiovascular diseases in Tehran, Iran. Data were analyzed using Graneheim and Lundman’s approach to identify subcategories and categories related to patient care needs, with the support of MAXQDA v20 software. Results: The participants included 16 women and 7 men, with an average age of 45.6 ± 10.9 years. Sixteen participants held a bachelor’s degree, two had a master’s degree, and five held a doctorate. Analysis of the interviews led to the extraction of 782 primary codes, which were classified into five main categories: Receiving Care from a responsive system, capacity building for the patient, receiving multidimensional care, having a comprehensive support system, and utilizing new caregiving technologies. Conclusions: The findings emphasize the importance of a holistic, patient-centered approach that prioritizes effective communication, seamless access to care, and continuity post-discharge.
ANALISIS PENGGUNAAN CHAT GPT (AI) DAN MODUL PEMROGRAMAN TERHADAP MOTIVASI BELAJAR DAN KREATIVITAS MAHASISWA DALAM MATA KULIAH PEMROGRAMAN PADA PROGRAM STUDI PENDIDIKAN TEKNOLOGI INFORMASI, UNIVERSITAS BINA BANGSA
Authors: Mutaqin Reihan , Desty Endrawati Subroto  , Cecep Warman
Published: November 2024

This research aims to analyze the use of CHAT GPT (AI) and Programming Module on students' understanding of programming in the Department of Information Technology Education at Bina Bangsa University. The research method used is a descriptive quantitative approach, with questionnaires distributed to 70 students as the population, and a sample of 35 students from two classes, namely 6A and 6B, was taken. The research subjects were given questionnaires, and the data were analyzed using the Likert scale as a measurement scale. The questionnaires were distributed through the Google Form platform. The results of the research show that the use of CHAT GPT (AI) is preferred by students in classes 6A and 6B in understanding programming concepts compared to the use of Programming Module. The utilization rate of CHAT GPT (AI) reaches 93.33% in class 6A and 75.24% in class 6B, while the utilization rate of Programming Module is only 75.91% in class 6A and 88.91% in class 6B. Therefore, CHAT GPT (AI) has good potential as a learning tool to help students understand programming concepts. The research results also indicate that the use of CHAT GPT (AI) and Programming Module has a positive impact on students' understanding in the programming course.
ANALISIS PENDAPATAN DAN NILAI TAMBAH AGROINDUSTRI KERIPIK PISANG (STUDI KASUS PADA UKM SELERAKU BANJARNEGARA)
Authors: Sarno Sarno , Kinding Dwi Putriana Nuramanah , Solekan Muhamad
Published: November 2024

UKM Seleraku is one of the businesses engaged in the agro-industry of banana chips in Banjarnegara Regency. The fundamental issue faced by UKM Seleraku is the lack of knowledge regarding the overall production costs and added value of the banana chips agro-industry they are involved in. The research aims to analyze the income and added value of the banana chips agro-industry. The basic research methods applied include case study and descriptive methods, as well as participatory action research. Data collection methods involve interviews, direct observation, and record-keeping. The data used in this research consists of two types: primary data and secondary data. The data analysis includes cost analysis, revenue analysis, income analysis, and added value analysis. Based on the research results, the findings are as follows: (1) UKM Seleraku incurs a total production cost for banana chips agro-industry amounting to IDR 10,090,000 per month, with fixed costs of IDR 3,350,000 and variable costs of IDR 6,740,000, (2) The total revenue generated by UKM Seleraku from the banana chips agro-industry is IDR 12,775,000 per month, while the income obtained is IDR 2,265,000 per month, (3) The added value of UKM Seleraku's banana chips agro-industry is IDR 68,750 per kilogram, calculated as the difference between the product value and the raw material cost, as well as other input values. This means that each kilogram of input (banana) generates an output (banana chips) worth IDR 68,750. The added value contributes 48.50 percent to the average output value in each production process. The added value ratio reaching 48.50 percent indicates the high value added from processing bananas into banana chips.
Implementasi Budaya Organisasi di Kantor Kesbangpolinmas Kota Kupang
Authors: Riwu Kore Jefirstson R , Fellyanus Haba Ora  , Moniche Aletha Saubaki
Published: November 2024

Tujuan penelitian ini adalah untuk menganalisis dan mendeskripsikan impelementasi budaya organisasi pegawai di Kantor Kesbangpolinmas Kota Kupang. Populasi pegawai sebanyak 31 orang menjadi sampel penelitian secara saturated sampling. Penelitian ini menggunakan data primer dan sekunder, melalui teknik perolehan data secara wawancara kusioner skala Likert dan dokumentasi. Analisis data secara deskripsi melalui skoring persepsi. Hasil penelitian menunjukkan implementasi budaya organisasi di Kesbangpolinmas Kota Kupang sudah sangat baik dari aspek orientasi hasil, orientasi tim kerja, keagresifan, dan stabilitas. Karakteristik individu pegawai menjadi perhatian organisasi untuk peningkatan kualitas pegawai, terutama dari aspek tingkatan pendidikan.
Penggunaan Pembayaran Non Tunai Quick Response Code Indonesia Standard (QRIS)
Authors: Hasanuddin Hasanuddin , Nisa Andi Khaerun , Rini Ferdiansyah , Nurliah Nurliah
Published: November 2024

The development of advanced technology and information will help the growth of the digital economy and accelerate the financial inclusion of a country. One form of implementation between information technology and digital economic growth includes non-cash transaction payments. So that people switch from conventional payments to digital payment models with the assumption that this digital payment model provides convenience and benefits. The purpose of this study is to determine what factors influence the ineffectiveness of the use of Non-Cash Quick Response Code Indonesian Standard (QRIS) payments by traders in Polewali Square, Polewali District, Polewali Mandar Regency. This type of research is qualitative research that builds meaning based on field data. This qualitative research procedure produces descriptive data in the form of written or spoken words from people and observable behavior. The results of the study indicate that the factors that influence the ineffective use of non-cash payments Quick Response Code Indonesian Standard (QRIS) by traders in the Polewali town square area, Polewali District, Polewali Mandar Regency are the lack of interest of traders and consumers to use the Quick Response Code Indonesian Standard (QRIS) as a means of payment in the town square area, the lack of socialization regarding QRIS, minimal knowledge about technological developments and the use of cash which is still the main means of payment among the community
Urgensitas Penerapan Asas-Asas Umum Pemerintahan Yang Baik Pada Konflik Rempang Eco City
Authors: Wafi Abd. , Mas'odi Mas'odi
Published: November 2024

This study examines how the implementation of the Principles of Good Governance (AAUPB) is crucial in addressing conflicts in Rempang Eco City. The conflict significantly impacts the central government's efforts to transform Pulau Rempang and its surroundings into a hub for trade, industry, and tourism, involving various stakeholders working on the environmental project. Consequently, to resolve the conflict on Pulau Rempang, it is crucial to incorporate the principles of good governance. The goal of applying these principles is to enhance transparency and accountability in governance. They will also aid in conflict resolution and encourage active participation of the community in project decision-making. This research also analyzes the case in Pulau Rempang to illustrate the challenges and prospects of implementing good governance principles in the context of environmental conflict. The research findings indicate that applying these principles can lead to more sustainable solutions beneficial to all parties involved in the Rempang Eco City conflict. Conversely, this study helps us understand the importance of implementing good governance principles in addressing similar environmental conflicts.
Peran Hukum dalam Pembangunan Ekonomi Nasional dan Industri Halal di Indonesia
Authors: Saniah Iah , Sholihah Nurlailiyah Aidatus
Published: November 2024

This study aims to explain the role of law in national economic development and halal industry in Indonesia. The writing method uses qualitative, primary and secondary data sources obtained from literature studies related to the role of law in national economic development and the halal industry, types of data in the form of qualitative, data collection techniques in the form of previous research, data analysis techniques in the form of descriptive. Based on research conducted, it shows that the halal industry in Indonesia has laws and regulations in building the national economy, and the halal industry. According to the Ministry of Finance of the Republic of Indonesia 2019, the halal industry plays an important role in building economic growth, one of which is the halal industry has donated, namely an investment of USD 1 billion, and has opened 127 thousand jobs every year. Based on the results of this study, it is stated that the role of law in national economic development and the halal industry in Indonesia is an appropriate regulation, such as designing halal industry norms and rules through halal certification, and can build growth and development of the national economy
Berperan Dalam Pembangunan SDM, Saatnya Insentif Guru Ngaji Bersumber Dari APBN
Authors: Baidowi Achmad
Published: November 2024

Well-consolidated human resource development must be supported by an adequate, targeted and equitable budget so that there is an increase in quality in the national education system in our country. There are 3 (three) parties in the national education system, namely students, education personnel, and educators. As the name implies, students are pupils or students who will undergo education or the learning process. Meanwhile, education personnel are parties who dedicate themselves and are appointed with the aim of supporting the implementation of education. While educators are education personnel who have qualified as teachers, lecturers, tutors, instructors, or the like, who participate in organizing education. Quran teachers take part as educators for the non-formal sector who already have qualifications and have participated a lot in organizing education in Indonesia. This study uses a qualitative approach with the method used in this study is the normative research method. The author's analysis uses conceptual analysis. The results of this study The Koran teacher as an educator is to direct students towards maturity with a perfect human personality, and the Koran teacher as a leader is able to control themselves, students and the community related to social problems. Budget allocation from the APBN is something that should be an effort to pay attention, appreciate and improve the welfare of Koran teachers
Effect of Biofertilizer and Foliar Applied Nutritive Compound on Growth, Yield and Chemical Composition of Spinach (Spinacia oleracea L.) In Sandy Soil
Authors: Mahmoud Asmaa R. Mahmoud , Lateef E.M. Abd El Lateef , Helmy Y.I. Helmy , Omar Nadia M. Omar , Khater Heba, M. Khater , El-Dewiny Camilia Y.
Published: November 2024

In order to emphasise on sustainable agricultural practices, alternative fertilization methods have
garnered attention, particularly bio-fertilizers known for their eco-friendly attributes and potential multifaceted benefits. Therefore, two field experiments were carried out at Experimental Farm, National Research Centre ElBehaira Governorate, Egypt to study the effect of nitrogen biofertilizer (Biogen), and Nutrin compound fertilizers on growth, yield and quality of spinach during two winter seasons of 2022/2023and 2023/2024. The results showed that inoculation of spinach seeds with Biogen had a positive effect of spinach plants by increasing the vegetative growth, as well as total fresh yield during the two growing seasons. Foliar fertilizer treatments revealed a notable trend; the higher dose of foliar application of Nutrin indicates significant effectiveness in promoting robust growth characteristics, as well as total yield during the two growing seasons. The results indicate that both biofertilizer treatments and foliar nutrient Nutrin act independently, therefore no evident interaction between the two treatments occurred. Highly significant effects due to Biogen or Nurtrin application to spinach were reported for N %, protein, P, K % significantly increased when Biogen was applied especially at the higher rate (2kg/fed)or Nutrin at (4 cm/l). Regarding the nitrate content of spinach leaves it is clear that the reported values were within the acceptable daily intake permitted. A highly significant positive correlation
coefficient between total fresh yield and N%, Crude protein % P% K% and nitrate content(ppm) were reported. (Fed= Feddan=4200m2)