bluuebunny/crossref_metadata_2025 huggingface dataset:
Morphometric analysis of transsphenoidal surgery in Peruvian population
Authors: Yataco-Wilcas Christian Alexander , Diaz-Llanes Bruno Eduardo , Coasaca-Tito Yosimar Salomon , Lengua-Vega Luis Alberto , Salazar-Campos Cristian Eugenio
Published: May 2024

Background:

Transsphenoidal surgery has become a key element in the approach to skull base pathologies. The objective of the study was to explore the morphometry of the sphenoidal region in the Peruvian population, with an emphasis on understanding its specific anatomical characteristics and providing quantitative data for the planning of transsphenoidal surgery.

Methods:

A cross-sectional study included a random sample of 81 cases of healthy individuals who presented to the Radiology Department of a Private Hospital Center in Peru over 1 year. Skull computed tomography scans without contrast were performed, and a detailed morphometric analysis was conducted by an expert neurosurgeon, including measurements of four parameters to evaluate the anatomy of the craniofacial region.

Results:

Most participants exhibited complete sellar pneumatization, followed by incomplete sellar pneumatization, while conchal pneumatization was rare. Significant differences were found between men and women in the distance from the nasal opening to the dorsum of the sella turcica. No significant gender differences were observed in other anatomical measurements or significant changes with age in anatomical measurements.

Conclusion:

Morphometric analysis provides crucial data for the precise customization of surgical interventions in the Peruvian population, especially in transsphenoidal surgery. The results highlight the importance of considering individual anatomical differences and gender variability during surgical planning. Morphometry emerges as a valuable tool to enhance the quality and safety of transsphenoidal surgery by adapting surgical strategies to the specific anatomical dimensions of each patient.
Iron-Catalyzed Late-Stage Radical C–H Alkylamination of Phenol-Containing Drugs and Biomolecules
Authors: Andrade-Sampedro Paula , Correa Arkaitz
Published: May 2024

A modular site-selective iron-catalyzed radical amination of a number of phenol-containing biomolecules such as tyrosine-containing peptides, estrogens and other phenol-based pharmaceuticals has been developed. The method features the use of the cost-efficient combination of FeBr3 as catalyst along with triflic acid as Brønsted acid, thereby enabling the predictable appendance of morpholine and related heterocycles at the ortho C–H bond of phenols in a late-stage fashion. This alkylamination technique leverages the electron-rich nature of phenols to undergo oxidation to the corresponding phenoxyl radicals and further coupling with in situ formed electrophilic aminium radical cation species.
M. A. Reichert: um flautista belga na corte do Rio de Janeiro
Authors: Dias Odette Ernest
Published: May 2024

Mathieu-André Reichert nasceu em Maestricht, Bélgica, em 1830. Veio para o Brasil em 1859, contratado pelo Imperador D. Pedro II, para tocar na Corte, onde foi brilhante. Morreu em 1880, no Rio de Janeiro.
Juventude e revolução: uma investigação sobre a atitude revolucionária juvenil no Brasil
Authors: Zaneti Hermes
Published: May 2024

Fruto de pesquisa, a presente obra pretende conhecer a relação existente entre juventude e revolução. Foi investigado se a idade influencia a atitude revolucionária e se o status socioeconômico da família do jovem, sua religião ou sua condição de estudante condicionam a influência da idade na atitude revolucionária. Demarcando como juventude o intervalo entre os 16 e os 25 anos, definiu a atitude revolucionária como a disposição de fazer revolução para atingir o objetivo de transformação social. O autor baseou-se na aplicação de um questionário de 87 perguntas em 21 cidades de todas as regiões do país, num total de 2.082 questionários, com 100% de aproveitamento, quando foram cruzadas mais de um milhão de informações. O autor fundamentou ainda o seu trabalho numa pesquisa qualitativa, realizando entrevistas com jovens, com lideres estudantis e políticos, com pesquisadores e estudiosos da área como, psicólogos, sociólogos e antropólogos. Realizou, igualmente, 14 entrevistas com revolucionários brasileiros da década de 1960.
Contribuições do desenvolvimento humano e da educação aos processos de inclusão: princípios, ensino superior e formação de professores - Volume 1
Authors: Maciel Diva
Published: May 2024

Como podemos desenvolver as práticas inclusivas? Os processos inclusivos são concretizados em escolhas cotidianas orientadas ao conhecimento mútuo e ao acolhimento, ao cuidado de si e entre pessoas com histórias diferentes. Refletir sobre os processos de desenvolvimento e aprendizagem das pessoas com necessidades especiais fortalece a geração de novas formas de ensinar, aprender e atuar. Nessa perspectiva, as organizadoras e os autores desta coletânea exploram a história, as políticas públicas, os serviços e o ensinar e aprender em constante inovação, a partir da problematização do cotidiano dos fazeres inclusivos. Esta obra é direcionada a estudantes, pesquisadores, educadores e outros profissionais de áreas afins e foi escrita em colaboração entre colegas de universidades e sistemas educacionais do Brasil, da Argentina e do Chile, psicólogos e professores das redes federal, distrital e municipais de ensino, membros de diferentes grupos de pesquisa e grupos de trabalho da ANPEPP que pesquisam e atuam inclusivamente. Recebeu apoio da UAB/Capes/MEC e UAB/UnB.
Custos no setor público
Authors: Silva César Augusto Tibúrcio
Published: May 2024

Como melhorar a gestão pública no Brasil? Uma resposta possível é fazê-lo por meio da melhor alocação dos recursos financeiros existentes. Nesse caso, existe uma necessidade premente de que o setor público possa dispor de uma contabilidade que traduza os eventos conforme sua competência. A adoção de uma contabilidade de custos é considerada fundamental para a melhoria da administração pública de qualquer país. Esta obra está dividida em duas partes principais. Na primeira, discute-se a importância da contabilidade de custos e sua adoção. A segunda parte vai além da teoria e do retrospecto histórico: apresenta casos práticos de adoção da contabilidade de custos na administração pública. Esses exemplos incluem diferentes serviços prestados pelo governo e mostram que é possível apurar custos no setor público. Uma obra crucial para gestores, pesquisadores, professores e profissionais da administração pública. É um livro que pode ser adotado no ensino de graduação e pós-graduação e em cursos de curta duração, nas disciplinas de Finanças Públicas, Contabilidade Pública, Administração Pública, Custos Aplicados, Programação Fiscal e Financeira, Controle e Avaliação da Gestão Pública.
New promising agents against COPD and asthma among the amides of 1-oxo-3-phenyl-isochroman-6-carboxylic acid
Authors: Nyporko Alex , Tsymbalyuk Olga , Voiteshenko Ivan , Starosyla Sergiy , Protopopov Mykola , Bdzhola Volodymyr
Published: May 2024

Background: Bronchodilators, which are compounds that can relax airway smooth muscle, are perhaps the most important component of combination therapy for chronic obstructive pulmonary disease, one of the most common non-communicable diseases in the world, which is the second most lethal disease after cardiovascular disease. Unfortunately, current clinical bronchodilators, whose activity is mediated by their interaction with muscarinic acetylcholine receptors, have side effects (up to myocardial infarction) due to their cross-affinity for different types of these receptors, including those prevalent in the heart muscle.

Objectives: The aim of this work is to search/develop compounds — effective bronchodilators capable of selectively inhibiting type 3 muscarinic acetylcholine receptors (M3 receptors), predominantly present in smooth muscles and not characteristic of cardiomyocytes.

Materials and Methods: High-throughput virtual screening of a collection of 150,000 compounds was conducted on the spatial structure of the M3 receptor, reconstructed in our previous studies. The effect of substances on contractile activity was investigated using tensometry in isometric mode on multicellular tracheal preparations. Antagonistic activity and type of inhibition were determined against the background of acetylcholine application (concentration range 10-10–10-3 M). To establish the affinity value of the compound-antagonist, the Schild regression equation was used.

Results: Based on virtual screening data, a series of compounds — amides of 1-oxo-3-phenyl-iso-chroman-6-carboxylic acid — were selected for biological testing. For two of these compounds (Compounds 1 and 7), the ability to selectively inhibit M3 receptors was demonstrated. Specifically, the affinity value pKB for Compound 1 was 7.28 ± 0.70, with an IC50 of 5.25·10-8 M. A critically important advantage of this compound is its ability, at equal concentrations, to more effectively inhibit signal transmission through M3 receptors compared to ipratropium bromide — a clinical cholinergic receptor inhibitor.

Conclusions: The sufficient effectiveness of inhibition and significantly increased selectivity of the studied compounds specifically towards M3 receptors provide strong grounds to consider these compounds as promising precursors of new generation cholinolytic drugs with targeted action on M3-type cholinergic receptors.
FPre-Operative Ultrasound Diagnostics of Mirizzi Syndrome
Authors: Bychkov S.O. , Saveliev V.V.
Published: May 2024

Background. Mirizzi syndrome (MS) is one of the most severe complications of the gastrointestinal tract and the most complex pathological process in biliary surgery in general. The issue of ultrasound diagnostics (USD) of MS in patients with gallstone disease (GLC) at the preoperative stage for planning the scope of surgical intervention and warning the patient about possible complications is acute. The goal. Determine the sensitivity of preoperative ultrasound in the diagnosis of MS and finding the most significant echo pattern of MS during ultrasound. Materials and Methods. The results of 9126 cholecystectomies performed in the Kharkiv Clinical Hospital on railway transport No. 2 for the period from 1997 to 2023 were analyzed, while MS was suspected in 159 (1.7%) patients by ultrasound. Out of 159 in whom signs of MS were detected by ultrasound, MS was reliably confirmed intraoperatively in 116 (72,9%) patients, and no SM was detected in 43 (27,1%) patients. MS I type was detected in 98 (84.49%) patients, MS II type – 18 (15.51%). Among them there were 87 (75) women, 29 (25) men, the age of the patients ranged from 37 to 80 years (on average – 66.4 years). To analyze the sensitivity of certain echo characteristics during preoperative ultrasound in case of suspicion of SM, the diagnostic sensitivity index (DS) was used. Results. It was established that the most sensitive echocardiogram is the absence of a clear border between the back wall of the gallbladder and the hepaticocholedochus, the frequency is 75.40%. The next sign of sensitivity, which was confirmed intraoperatively, is a shrunken gall bladder, the DS indicator is 54.55%. It was also established that the combination of such echo features as: a shrunken gallbladder and the absence of a clear border between the back wall of the gallbladder and hepatic choledochal, which was detected in 25, in 23 of them, MS was confirmed intraoperatively, the DS rate was 92%. Conclusions. Ultrasound allows with a high (72,9%) degree of probability to establish the presence of SM at the preoperative stage. A reliable ultrasound sign of the presence of SM is the visualization of the common wall between the gallbladder and the hepaticocholedochus – DS 75.40%. With a combination of echo signs: shrunken gallbladder and deformation of the wall of the hepaticocholedochus in the place of attachment of the gallbladder, it is possible to assume MS with a high percentage of reliability (92%) with the help of ultrasound at the preoperative stage. The received information about the high probability of the presence of MS before the operation allows you to correctly plan possible options for the volume and tactics of surgical intervention.
An evidence-based algorithmic approach to osteoporosis etiology verification on the example of a clinical case
Authors: Barabash N.Y. , Kostina T.V. , Tykhonova T.M.
Published: May 2024

Background. The importance of timely detection of osteoporosis in patients is conditioned by its severe consequences such as osteoporotic fractures. The disease can be both primary and related to the existing other pathology or to the therapy being carried out, i.e. secondary. In young patients, in most cases, osteoporosis is secondary in nature. Diagnosis verification requires doctor’s perseverance and knowledge. Purpose – is to demonstrate an algorithm of finding a possible cause of the osteoporosis development in a young person on the example of a clinical case. Materials and Methods. The medical history of a 32-year-old man is presented. The man was consulted a doctor with complaints of long-lasting aching pain in the back, stiffness in the morning in the thoracic spine and pain during movement, and was diagnosed with a compression fracture of the spine on the background of a decrease in bone mineral density. Results. The article describes the step-by-step algorithm of making a diagnosis by gradually excluding primary osteoporosis and possible causes of the secondary nature of the disease. Information about the possible mechanisms of osteoporosis formation in the most common conditions included to the differential diagnosis is given in the article. The described diagnostic search algorithm can be used in the practice of a doctor of any specialty. Conclusions. Making a diagnosis of osteoporosis must include a differential diagnosis of its forms with the establishment of the ethiology of this pathology. In young patients, in most cases, osteoporosis has secondary nature and requires a mandatory search for its cause by gradually and methodically excluding conditions that can lead to a decrease in the mineral density of bone tissue, including genetic ones. In practice, there are cases of idiopathic osteoporosis, when the examination does not allow to clearly establish the reasons that led to a decrease in bone density. Such cases require the special attention of doctors, because the diagnosis of the main disease that led to the development of osteoporosis in the future can be detected. In this case along with antiresorptive drugs, therapy of the condition, which is the root cause of the development of osteoporosis, is prescribed, if possible. The specified combined therapy will contribute to increasing the effectiveness of treatment and shortening its duration.
Analysis of the Effect of Quality Control Circle on the Central Sterile Supply Department
Authors: Kong Xiaoxiao
Published: May 2024

Objective: To analyze the effect of quality control circle on the central sterile supply department (CSSD). Methods: The control group and the observation group each consisted of 180 instruments received by the sterilization supply center from January to March 2023 and 11 CSSD staff. The control group underwent routine management while quality control circle was implemented in the observation group. The quality of work, disinfection and sterilization qualification rates, disinfection and sterilization of various instruments, cleaning indicators, and management satisfaction of both groups were compared. Results: The observation group scored higher in terms of work quality, the qualification rate of disinfection and sterilization in each link, the disinfection and sterilization of instruments, and cleaning indicators compared to the control group. Besides, the management satisfaction of the observation group was higher than that of the control group (P < 0.05). Conclusion: A quality control circle ensures the quality of work, improves the cleaning, disinfection, and sterilization of instruments of the CSSD, and improves the management satisfaction of the CSSD staff.
Effect of Comprehensive Nursing Intervention in Patients with Urinary Incontinence After Radical Prostatectomy
Authors: Zhong Haiqin
Published: May 2024

Objective: To explore and analyze the clinical effect of comprehensive nursing intervention in patients with urinary incontinence after radical prostatectomy. Methods: 84 patients with urinary incontinence after radical prostatectomy admitted to the Urology Department between May 2021 and May 2023 were included in this study. The patients were divided into a comprehensive group and a control group, with 42 cases in each group through a double-blind mechanism. The comprehensive group received comprehensive nursing care, and the control group received primary nursing care. The duration of indwelling urinary catheters and urinary incontinence; psychological performance and living conditions were compared between the two groups. Results: The duration of the indwelling urinary catheter and urinary incontinence of the patients in the comprehensive group were significantly shorter than that in the control group (P < 0.05). Before nursing, there was no statistically significant difference in the anxiety, depression, and other psychological manifestations between the two groups (P > 0.05); after nursing, the comprehensive group’s anxiety, depression, and other psychological manifestations of the comprehensive group were significantly lower than those of the control group (P < 0.05). Before nursing, there was no statistically significant difference in the physical function, mental state, emotional state, and physical recovery of the patients between both groups (P > 0.05); after nursing, the physical function, mental state, emotional state, physical recovery of the patients in the comprehensive group were significantly better than those of the control group. Besides, the living conditions of the patients in the comprehensive group were also significantly better than the control group’s (P < 0.05). Conclusion: Comprehensive nursing intervention can effectively improve symptoms of urinary incontinence after radical prostatectomy, reduce inner pressure, and improve living standards.
Application Value of Nursing Intervention for Patients with Pancreatitis After Endoscopic Retrograde Cholangiopancreatography (ERCP)
Authors: Shan Haixia , Zhou Wei , Cai Yanyan , Zhou Fang , Hu Yuling
Published: May 2024

Objective: To explore and analyze the application value of nursing intervention for patients with pancreatitis after endoscopic retrograde cholangiopancreatography (ERCP). Methods: From May 2022 to May 2023, 100 patients with pancreatitis after ERCP who were admitted to the General Surgery Department of our hospital were selected as the research objects, they were divided into a research group and a general group by flipping coins, with 50 cases in each group. The research group received nursing intervention, and the general group received general nursing. The postoperative index recovery time, quality of life, and emotional performance were compared between the two groups. Results: The blood amylase recovery time, abdominal pain recovery time, white blood cell recovery time, and hospitalization time in the research group were significantly lower than those in the general group (P < 0.05). Before intervention, the physical function, social factors, physiological performance, emotional state, and other quality of life indicators were compared between the groups, and there was no statistically significant difference (P > 0.05); after intervention, the mentioned quality of life indicators were significantly better than that of the general group (P < 0.05). Before intervention, the Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) scores between the groups were compared, and there was no statistically significant difference (P > 0.05); after intervention, the SAS and SDS scores of the research group were significantly better than those of the general group (P < 0.05). Conclusion: The application of nursing intervention in patients with pancreatitis after ERCP has high clinical value and specific practical significance.
The Effect of Psychosocial Nursing on Elderly Patients with Chronic Obstructive Pulmonary Disease
Authors: Liang Li
Published: May 2024

Objective: To explore the clinical effect of psychosocial nursing in elderly patients with chronic obstructive pulmonary disease (COPD). Methods: The sample of this study included 100 elderly patients with COPD who were admitted to our hospital from January 2021 to June 2023. They were divided into a research group (n = 50) and a control group (n = 50). The patients in the two groups received essential nursing intervention, and those in the study group received psychological nursing intervention along with it. The Hamilton Anxiety Rating Scale (HAM-A), Hamilton Depression Rating Scale (HAM-D), quality of life score, and nursing satisfaction of the two groups were compared. Results: After the nursing intervention, the HAM-A score and HAM-D score of the research group were lower than those of the control group (P < 0.05), and the quality-of-life score and the nursing satisfaction of the research group were higher than that of the control group (P < 0.05). Conclusion: Psychosocial nursing for elderly patients with chronic obstructive pulmonary disease can enhance their emotional well-being, quality of life, and satisfaction with nursing care, demonstrating its potential for broader application and adoption.
The Effect of Azithromycin in Treating Mycoplasma Pneumonia in Children
Authors: Zhou Hong , Xu Hongjuan , Wang Lihong , Fang Shuying , Zhang Yehua
Published: May 2024

Objective: To discuss and analyze the effect of azithromycin in the treatment of mycoplasma pneumonia in children. Methods: A total of 120 children with mycoplasma pneumonia who were admitted to the Department of Pediatrics of our hospital from January 2022 to December 2022 were selected as the research subjects. They were divided into an azithromycin group and a reference group according to the random number drawing method, with 60 cases in each group. The azithromycin group was treated with azithromycin, and the reference group was treated with conventional treatment. The efficacy of treatment, laboratory indicators, platelet count and D-dimer, and adverse reactions of both groups were compared. Results: The efficacy of the azithromycin group was significantly higher than that of the reference group (P < 0.05). Before treatment, there were no significant differences in the laboratory indicators like ferritin, procalcitonin (PCT), and erythrocyte sedimentation rate (ESR) between the two groups (P > 0.05); after treatment, the laboratory indicators of the azithromycin group were significantly better than those of the reference group (P < 0.05). Before treatment, there was no statistically significant difference in platelet count and D-dimer between the groups (P > 0.05); after medication, the platelet count, and D-dimer in the azithromycin group were significantly better than those in the reference group (P < 0.05). The total incidence of adverse reactions in the azithromycin group was significantly lower than that in the reference group (P < 0.05). Conclusion: Azithromycin is more effective in treating mycoplasma pneumonia in children, and has certain clinical value.
Application of PDCA Cycle in Hand Hygiene Management of Psychiatric Medical Staff
Authors: Xiang Li , Liu Weidong , Chen Guiying , Liu Mei
Published: May 2024

Objective: To study the application effect of the plan-do-check-act (PDCA) cycle management in the hand hygiene management of psychiatric medical staff. Methods: One hundred and twenty medical staff from a psychiatric hospital from May 2023 to December 2023 were selected and divided into two groups. The control group (May 2023 to August 2023) applied the conventional management model, and the observation group (September 2023 to December 2023) applied the PDCA cycle management. The hand hygiene compliance, hand hygiene knowledge, and hygiene qualifications were compared, including the amount of hand sanitizer used. Results: The proportion of medical staff’s hand hygiene compliance and hand hygiene knowledge mastery scores in the observation group were higher than those in the control group (P < 0.05); the hand hygiene passing rate in the observation group was higher than that of the control group (P < 0.05); the daily amount of hand sanitizer per patient bed and the amount of hand sanitizer used was higher than that of the control group (P < 0.05). Conclusion: The PDCA cycle management model for psychiatric medical staff promoted the improvement of hand hygiene compliance and increased their hand hygiene qualifications. It is suitable for further popularization and application in future clinical practice.
Study on the Application Effect of Flexible Nursing Care in Patients with Postpartum Urinary Retention and its Effect on Lactation
Authors: Zhu Hongyan
Published: May 2024

Objective: To study the application effect of flexible nursing in patients with postpartum urinary retention and its effect on lactation. Methods: A total of 200 cases of postpartum urinary retention patients admitted between January 2021 and January 2022 were selected and randomly grouped into two groups, a control group (conventional nursing) and an observation group (flexible nursing), of 100 cases each. The time of onset of lactation, the lactation volume score, urinary indicators, the amount of post-partum hemorrhage, and the quality of life score of the two groups were compared. Results: The observation group’s lactation initiation time (21.41 ± 1.52) h and lactation volume score (2.11 ± 0.52) were better than that of the control group (P < 0.05). The observation group’s first urination time (2.11 ± 0.51) min was lower than the control group, while the urinary retention completely relieved time (33.12 ± 8.61) h, and first urinary volume (262.17 ± 52.41) mL was higher than that of the control group (P < 0.05). The amount of postpartum hemorrhage in the observation group (151.21 ± 22.12) mL was less than that in the control group (P < 0.05). The scores of somatic functioning (86.25 ± 2.20), psychological functioning (91.56 ± 1.45), social functioning (89.25 ± 2.45), and material life (89.75 ± 1.45) of the observation group were higher than those of the control group after nursing (P < 0.05). Conclusion: Flexible nursing care in patients with postpartum urinary retention exhibited significant nursing effects and lactation function was effectively improved.
Clinical Analysis of Common Irrational Gastroenterology Medication Problems in The Gastroenterology Department
Authors: Cong Fengmei
Published: May 2024

Objective: To investigate and analyze the irrational problems of common gastroenterology medications applied to gastroenterology patients during treatment, and to develop and implement countermeasures. Methods: This study included 60 patients admitted to the Department of Gastroenterology from January 2021 to December 2023 who were randomly divided into a control group (conventional drug management) and an observation group (targeted drug treatment), of 30 cases each. After the implementation of different management methods, the occurrence of irrational drug use and the incidence of adverse reactions between both groups were compared and statistically analyzed. Results: The incidence of irrational medication in the observation group (13.33%) was lower than that in the control group (40.00%) (P < 0.05). The occurrence of adverse reactions in the observation group (10.00%) was lower than that of the control group (36.67%) after treatment (P < 0.05). The observation group had a higher level of satisfaction after treatment (90.00%) as compared to the control group (66.67%) (P < 0.05). Conclusion: Implementation of targeted drug treatment for gastroenterology patients reduced the incidence of irrational medication use, reduced adverse reactions, and improved patient satisfaction.
Analysis of Innovative and Adaptive Higher Education Curriculum Development to Education 5.0 Based Challenges in Indonesia
Authors: Hutahaean Berman , Telaumbanua Sadieli , Tamba Losten , Hutabarat Renato Gema Nugraha , Sumani Sumani
Published: May 2024

This study comprehensively analyzes the evolving landscape of higher education curriculum development in response to the advent of Education 5.0 in Indonesia. Recognizing the seismic shifts prompted by digital transformation and the Fourth Industrial Revolution, the research identifies the imperative to realign educational frameworks to foster twnet-first-century competencies and technological integration and enhance lecturers’ capabilities. This research aims to analyze the development of an innovative and adaptive higher education curriculum to the challenges based on Education 5.0 in Indonesia. Through a qualitative methodology encompassing case studies of three Indonesian universities that have pioneered innovative and adaptive curricula, the investigation sheds light on the strategic orientations and methods employed. Core informants and supporting informant data were amassed through interviews, observations, and documentary analysis involving key stakeholders: universities, industry, government and community representatives. Employing the Miles and Huberman model for data analysis, the findings underscore the necessity for curricula that not only imbibe technological advancements orienting toward twenty-first-century competencies but also integrate technology, humanities and local wisdom in learning prioritize flexibility, learner personalization and stakeholder collaboration in curriculum development and execution. Furthermore, the study highlights the critical role of continuous evaluation and accreditation in upholding curriculum quality and credibility. Collectively, these insights contribute to delineating a framework for higher education curricula that are equipped to meet the demands of Education 5.0, thereby serving as a beacon for curriculum developers, policymakers and educational practitioners aiming to navigate the complexities of contemporary educational dynamics.
Bridging Content and Language in English-medium Engineering Programs
Authors: Wilang Jeffrey Dawala , Ngamchatturat Thanatcha , Seepho Sirinthorn
Published: May 2024

English-medium Instruction (EMI) is increasingly being implemented in diverse educational settings where English is not the primary language. However, a persistent challenge of EMI implementation lies in the scarcity of high-quality EMI teaching materials that effectively enhance both content knowledge and language acquisition. This study aimed to investigate how language is integrated with content in EMI lessons and to assess their efficacy. The study involved three Civil Engineering teachers, three language teachers, and 102 students. Data collection instruments comprised journals kept by content and language teachers during the EMI materials development process, pre-tests and post-tests, satisfaction surveys, and semi-structured interviews. The quantitative results were analyzed using descriptive statistics and t-tests, while content analysis was used to analyze qualitative data. Results revealed that students expressed high satisfaction with the materials, noting increased participation in EMI classes, enhanced content comprehension, and heightened awareness of language use in lessons. Nonetheless, the design process of EMI materials is intricate, non-linear, time-consuming, and demanding of pedagogical expertise. While collaborative efforts between content and language teachers have appeared promising in theory, practical implementation in real contexts has proven to be challenging. It is recommended that the EMI materials developers possess pedagogical knowledge on content and language teaching, recognize the iterative and complex nature of the material design process, and the need for ongoing communication with the respective to enhance the success of the collaboration.
Ukázka působení a činnosti pražského arcibiskupství za arcibiskupa Zbyňka Berky z Dubé a Lipé
Authors: Syslová Anna
Published: May 2024

Příspěvek je sondou do církevních a náboženských poměrů přelomu 16. a 17. století z perspektivy pražského arcibiskupství prostřednictvím osoby desátého pražského arcibiskupa Zbyňka Berky z Dubé a Lipé (1551–1606). Je představeno arcibiskupovo rodinné zázemí, mocenské pozice nejbližších příbuzných a jeho cesta za církevními beneficii, která je zakončena rokem 1592 a ziskem svatovojtěšského stolce. Následná stěžejní pasáž pojednává o Berkově rekatolizační činnosti a s ní spojené působení nunciů na pražském císařském dvoře. Článek nastiňuje složitou náboženskou situaci doby a způsoby aplikovaného rekatolizačního postupu, který se snaží interpretovat na základě rozboru arcibiskupské korespondence.
Litevci, Estonci a Lotyši: udávání tempa glasnosti a perestrojky v sovětské historiografii
Authors: Lipinsky Jan
Published: May 2024

Litevci, Estonci a Lotyši: udávání tempa glasnosti a perestrojky v sovětské historiografiiEstonsko, Lotyšsko a Litva byly v důsledku paktu Ribbentrop-Molotov začleněny do Sovětského svazu, čímž se obyvatelé Pobaltí stali národnostními menšinami v rámci sovětského státu. Od druhé světové války bojovaly pobaltské národy proti sovětské hegemonii za zachování své národní identity a znovuzískání suverenity. V tomto boji hrálo stále větší roli připomínání historie, zejména pokud jde o roky 1939 a 1940. Od osmdesátých let 20. století umožnilo úsilí pobaltských zemí stále svobodnější historiografickou a politickou diskuzi. Tyto debaty, prezentace a publikace ukázaly, jak procesy zdola mohou určovat trendy, ovlivňovat politické programy a položit základy pro osvobození jak svých pobaltských vlastí od sovětské hegemonie, tak sovětsko-ruské historiografie od totalitních direktiv. Litevci, Estonci a Lotyši udávali tempo sovětské historiografii v gorbačovské éře. Našli svůj politický hlas a vydláždili cestu svobodné pobaltské budoucnosti.
Outbreak of Listeria monocytogenes in hospital linked to a fava bean product, Finland, 2015 to 2019
Authors: Otte im Kampe Eveline , Salmenlinna Saara , Åberg Riikka , Wallgren Suvi , Hautaniemi Maria , Keronen Satu , Leinonen Elina , Pihlajasaari Annika , Ruotsalainen Eeva , Sarvela Anna , Rimhanen-Finne Ruska
Published: May 2024

Listeria monocytogenes (Lm) is a bacterium widely distributed in the environment. Listeriosis is a severe disease associated with high hospitalisation and mortality rates. In April 2019, listeriosis was diagnosed in two hospital patients in Finland. We conducted a descriptive study to identify the source of the infection and defined a case as a person with a laboratory-confirmed Lm serogroup IIa sequence type (ST) 37. Six cases with Lm ST 37 were notified to the Finnish Infectious Diseases Registry between 2015 and 2019. Patient interviews and hospital menus were used to target traceback investigation of the implicated foods. In 2021 and 2022, similar Lm ST 37 was detected from samples of a ready-to-eat plant-based food product including fava beans. Inspections by the manufacturer and the local food control authority indicated that the food products were contaminated with Lm after pasteurisation. Our investigation highlights the importance that companies producing plant-based food are subject to similar controls as those producing food of animal origin. Hospital menus can be a useful source of information that is not dependent on patient recall.
Anorectal lymphogranuloma venereum among men who have sex with men: a 3-year nationwide survey, France, 2020 to 2022
Authors: Peuchant Olivia , Laurier-Nadalié Cécile , Albucher Laura , Balcon Carla , Dolzy Amandine , Hénin Nadège , Touati Arabella , Bébéar Cécile ,   on behalf of the Anachla study group
Published: May 2024

Background

In France, lymphogranuloma venereum (LGV) testing switched from universal to selective testing in 2016.

Aim

To investigate changes in LGV-affected populations, we performed a nationwide survey based on temporarily reinstated universal LGV testing from 2020 to 2022.

Methods

Each year, during three consecutive months, laboratories voluntarily sent anorectal Chlamydia trachomatis-positive samples from men and women to the National Reference Centre for bacterial sexually transmitted infections. We collected patients’ demographic, clinical and biological data. Genovars L of C. trachomatis were detected using real-time PCR. In LGV-positive samples, the ompA gene was sequenced.

Results

In 2020, LGV positivity was 12.7% (146/1,147), 15.2% (138/907) in 2021 and 13.3% (151/1,137) in 2022 (p > 0.05). It occurred predominantly in men who have sex with men (MSM), with rare cases among transgender women. The proportion of HIV-negative individuals was higher than that of those living with HIV. Asymptomatic rectal LGV increased from 36.1% (44/122) in 2020 to 52.4% (66/126) in 2022 (p = 0.03). Among users of pre-exposure prophylaxis (PrEP), LGV positivity was 13.8% (49/354) in 2020, 15.6% (38/244) in 2021 and 10.9% (36/331) in 2022, and up to 50% reported no anorectal symptoms. Diversity of the LGV ompA genotypes in the Paris region increased during the survey period. An unexpectedly high number of ompA genotype L1 variant was reported in 2022.

Conclusion

In rectal samples from MSM in France, LGV positivity was stable, but the proportion of asymptomatic cases increased in 2022. This underscores the need of universal LGV testing and the importance of continuous surveillance.
Analisis Fisiologi Stek Pucuk dalam Perbanyakan Eucalyptus pellita F. Muell Tanpa Menggunakan Hormon
Authors: Fadhlurrahman Muhammad Miftah , Budi Sri Wilarso , Wulandari Arum Sekar
Published: May 2024

Jenis tanaman yang umum digunakan di Hutan Tanaman Industri (HTI) sebagai bahan baku pulp dan kertas adalah Eucalyptus pellita. Bibit berkualitas E. pellita salah satunya diproduksi dari klon unggul dengan perbanyakan secara vegetatif, yakni stek pucuk. Terdapat hasil penelitian yang menunjukkan bahwa perbanyakan klon tertentu memiliki nilai keberhasilan hidup tertinggi dengan perlakuan tanpa menggunakan hormon tambahan. Oleh karena itu perlu dilakukan penelitian perbanyakan bibit stek E. pellita tanpa menggunakan hormon. Hasil analisa fisiologi stek pucuk E. pellita menunjukkan setiap parameter yang diamati yakni kandungan hormon IAA, nilai C-organik, dan nilai N yang diamati menunjukkan hasil yang tidak linear dengan perlakuan umur tunas. Hasil pengukuran panjang tunas, jumlah node, dan jarak antar node menunjukkan nilai yang linear dengan perlakuan umur tunas. Hasil pengamatan total hidup (Survival Rate), total berakar dan bertunas menunjukkan perlakuan umur tunas 18 hari memiliki nilai terendah dibandingkan perlakuan lain. Pada umur 2 MST menunjukkan perlakuan umur tunas 21 hari memiliki kemampuan pertumbuhan akar paling cepat dibandingkan perlakuan lain. Berdasarkan hasil pengukuran tinggi dan diameter umur 12 MST menunjukkan perlakuan tunas umur 21 hari memiliki pertumbuhan dan Survival Rate terbaik sehingga dapat menjadi dasar penentuan umur tunas dalam produksi bibit klon 148 skala operasional.
Kata kunci: E. pellita, fisiologi, perbanyakan, hormon
CUIDADO INTEGRAL À SAÚDE DAS PESSOAS VIVENDO COM HIV A PARTIR DA COORDENAÇÃO E ORDENAÇÃO DA ATENÇÃO PRIMÁRIA
Authors: PACHECO ANDRESSA KELINE FREITAS , BRAGA AMANDA MARIA MENDES , ROSA GABRIEL JOSÉ VIANA , MARTINS JULIANE MORAIS , SOUSA LAYLA LETÍCIA ALVES DE , MATOS TÁBITA ADÁLIA DE OLIVEIRA DE , CABRAL WENDY VITÓRIA MARTINS , SOUSA ANDREYNA SOUSA DE , TRAVASSOS MARIA JULIA SILVA , LIMA SILVIA CRISTINA VIANA SILVA
Published: May 2024

Descrever os avanços e entraves da Atenção Primária à Saúde (APS) sobre o cuidado
integral às Pessoas Vivendo com HIV/AIDS (PVHA). Trata-se de uma revisão integrativa
da literatura cuja busca foi realizada nas bases de dados MEDLINE, LILACS e BDENF,
utilizando os descritores "Cuidados Integrais de Saúde", "HIV", Direito à Saúde” e
"Promoção da Saúde". Foram identificados 119 estudos, sendo selecionados 8 artigos
para análise e documentos oficiais do Ministério da Saúde. O cuidado integral à saúde
das PVHA no Sistema Único de Saúde (SUS), coordenado pela APS, é fundamental para
aprimorar a qualidade de vida desse grupo. Destacam-se ações cruciais para o avanço na
organização dos cuidados às PVHA, como a criação dos Centros de Testagem e
Aconselhamento (CTA), a descentralização da atenção às PVHA pela equipe da
Estratégia Saúde da Família (ESF), a integração e a descentralização dos Testes Rápidos
(TR) para o HIV. Como estratégias complementares, tem-se a oferta de kits de autotestes,
os avanços na criação de fármacos antirretrovirais, e as inovações na prevenção
combinada. Embora apresente avanços relevantes, os cuidados às PVHA enfrentam
desafios, como a necessidade de estabelecer fluxos de atendimento, a carência de
capacitações para os profissionais, a ausência de prontuários eletrônicos integrados e a
falta de comunicação entre a equipe. Entretanto, por meio dos estudos, notou-se que a
APS tem o potencial de criação de um modelo de atenção à saúde inclusivo, integral e
capaz de reconhecer as necessidades e as limitações. A coordenação e a ordenação da APS
são frutos de mudanças sociais que possibilitaram a amplitude da linearidade do cuidado
às PVHA sob os princípios organizacionais e doutrinários preconizados pelo SUS.
Todavia, existem entraves que excedem a governabilidade da equipe de saúde,
envolvendo aspectos de vulnerabilidades, individual e social.
OS DESAFIOS AO ACESSO À SAÚDE COMO UM DIREITO FUNDAMENTAL
Authors: FERREIRA ALLAN BERTHIER SILVA , SILVA CÁSSIA MARA ALEXANDRINO , SOUSA DAYANE FERNANDES , SOUSA MIRNA RIBEIRO FREITAS DE , LIMA ADEÂNIO ALMEIDA , DINIZ JÉSSICA MARIA GABRIELA DA SILVA , LIMA SÉRGIO DA SILVA , SIQUEIRA ELISANDRA LOCH DE , OLIVEIRA AMANDA RODRIGUES MENDES DE , PEREIRA LETÍCIA MELO
Published: May 2024

Analisar os desafios ao acesso à saúde como um direito fundamental. Trata-se de uma
revisão integrativa da literatura. A coleta de dados ocorreu por meio da consulta às bases
de dados LILACS, SciELO, PubMed e Scopus utilizando os descritores “Sistema Único
de Saúde” AND “Saúde Pública” AND “Planejamento em Saúde”. Os desafios ao acesso
à saúde como um direito fundamental no Brasil são multifacetados e incluem taxas
elevadas de cesarianas, queda na cobertura vacinal, desigualdades socioeconômicas e
geográficas, judicialização da saúde, disparidades na realização de exames preventivos e
limitações no acesso aos serviços de saúde para populações vulneráveis, como pessoas
em situação de rua e mulheres privadas de liberdade. Conclui-se que a superação desses
desafios requer ações integradas, políticas públicas equitativas e maior participação da
comunidade na gestão da saúde, garantindo que o acesso à saúde seja verdadeiramente
universal e um direito humano fundamental para todos os cidadãos brasileiros.
COLETÂNEA DE ESTUDOS EM SAÚDE, REABILITAÇÃO E TECNOLOGIA
Authors: Silva Maria Sofia Santos da , Lima Raffaela Silva de , Rodrigues Luzimara Vieira , Costa Maria de Fátima Góes da , Vieira Júlia Gabrielly de Sousa , Silva Fernanda Estumano da Silva e , Nogueira Estefany Raiane da Silva , Queiroz Wiviane do Espírito Santo Costa , Oliveira Luzianne Fernandes de , Silva Rayanne Medeiros da , Martins Claudia Maria da Rocha , Souza Isabela de Nazaré Tavares Cardoso , Souza Murilo dos Santos , Silva Ana Beatriz Dias , Rodrigues Júnior Jorge Lopes , Bessa Rogério Ferreira , Brito João Amaury Francês , Sá Nonato Márcio Custódio Maia , Santana Ingrid Estheffani Calil , Mendes Michely Caroline Nascimento , Mello Nathalia Castilhos , Batista Paula Rayane Oliveira , Rodrigues Neto Jorge Lopes , Cunha Israel Fernandes de França , Silva Estéfane Costa da , Paranhos Alna Carolina Mendes , Koury Gisele Vieira Hennemann , Dias Ápio Ricardo Nazareth , Launé Beatriz Freitas , Quaresma Juarez Antônio Simões , Falcão Luiz Fábio Magno , Souza Givago Silva , Barreto Hellany Manuela da Cruz , Souza Yasmim Jamilly Carneiro de , Silva Pietra Araújo da , Morais Victor Hugo Martins de , Moura Ana Carolina Tavares , Almeida Maria Regina Cardoso de , Bentes Joubert Marinho da Silva , Santos Lidiane Palheta Miranda dos , Dantas Fernando da Cunha , Sodré Giovanna Gonçalves , Canuto Márcio Gabriel dos Santos , Souza Ana Beatriz dos Santos , Rodrigues Mateus Gabriel Muniz , Rondon Douglas Rolando Pena , Silva Elane do Socorro Oliveira da , Moraes Márcia Goretti Guimarães de , Cota Karen Regina Ferreira
Published: May 2024

O presente e-book de produção científica publicado sob o título de Coletânea de Estudos em Saúde, Reabilitação e Tecnologia reúne um conjunto de trabalhos científicos oriundos de pesquisas desenvolvidas por profissionais que compõem a equipe do Centro Especializado em Reabilitação III (CER III), da Unidade de Ensino e Assistência em Fisioterapia e Terapia Ocupacional (UEAFTO) da Universidade do Estado do Pará (UEPA). Trata-se de uma publicação original de pesquisas científicas conduzidas pela equipe multiprofissional que compõe o CER III, realizadas em parceria com atividades de ensino, sejam com discentes dos cursos da UEPA, no espaço do CER III, por residentes da Residência Multiprofissional da UEPA ou como fruto de pesquisas quantitativas, empíricas e/ou relatos de experiência, a partir da assistência prestada à população por essa equipe, no âmbito do Sistema Único de Saúde (SUS).
PRODUÇÃO E ELABORAÇÃO DE CARTILHA: técnica de conservação de energia na saúde funcional do idoso
Authors: Santos Lidiane Palheta Miranda dos , Dantas Fernando da Cunha , Paranhos Alna Carolina Mendes , Sodré Giovanna Gonçalves , Canuto Márcio Gabriel dos Santos
Published: May 2024

A Terapia Ocupacional é definida como uma profissão de nível
superior, a qual se utiliza, de forma terapêutica, das ocupações cotidianas dos indivíduos nas suas intervenções. Possui como objetivo possibilitar ou restabelecer a participação em ocupações, reforçando papéis ocupacionais, hábitos e rotinas de seus clientes. O terapeuta ocupacional utiliza de seus saberes e conhecimentos sobre a relação entre o cliente, o envolvimento desses em ocupações significativas e o contexto para designar o tratamento enfatizado na ocupação (AOTA, 2020).
O BENEFÍCIO DO USO DAS TECNOLOGIAS ASSISTIVAS POR PESSOAS COM PERDA AUDITIVA: uma revisão de literatura
Authors: Vieira Júlia Gabrielly de Sousa , Silva Fernanda Estumano da Silva e , Nogueira Estefany Raiane da Silva , Queiroz Wiviane do Espírito Santo Costa , Oliveira Luzianne Fernandes de
Published: May 2024

A perda auditiva se configura como uma deficiência que gera
“redução ou perda na capacidade de ouvir os sons” (Gonçalves, 2022, p. 2). Dito isso, é fato que esta condição pode afetar a capacidade de comunicação, interação social e aprendizado do indivíduo que a possui, sendo necessários meios para contornar possíveis dificuldades nesses
âmbitos. O avanço tecnológico trouxe consigo uma nova esfera de possibilidades, as denominadas “tecnologias assistivas”, que visam auxiliar às pessoas com deficiência em atividades do cotidiano, na integração social, bem como a melhora no processo de ensinoaprendizagem (Lisboa; Barroso; Rocha, 2020).
PERFIL EPIDEMIOLÓGICO DE PACIENTES COM PARALISIA CEREBRAL ASSISTIDOS PELO SERVIÇO DE ORTOPEDIA DA OFICINA ORTOPÉDICA FIXA/CERIII/UEAFTO/CCBS/UEPA
Authors: Souza Isabela de Nazaré Tavares Cardoso , Souza Murilo dos Santos , Silva Ana Beatriz Dias , Rodrigues Júnior Jorge Lopes , Bessa Rogério Ferreira , Brito João Amaury Francês , Sá Nonato Márcio Custódio Maia
Published: May 2024

A Paralisia Cerebral, ou também denominada como
encefalopatia crônica não progressiva da infância, é uma condição neurológica estática resultante de lesão cerebral, que ocorre antes que o desenvolvimento do cérebro esteja completo, mais especificamente, durante o período pré, peri ou pós-natal (Krigger, 2006; Dantas; Calomeni; Mendonça, 2022). A Paralisia Cerebral é caracterizada como imutável, permanente e não progressiva ao tecido nervoso em um estágio inicial de desenvolvimento. No entanto, apesar da lesão cerebral ser irreversível, a plasticidade do Sistema Nervoso Central (SNC) contribui para que as regiões cerebrais funcionantes substituam mesmo que parcialmente as funções perdidas (Mlodawski, 2019).