bluuebunny/crossref_metadata_2025 huggingface dataset:
Formation of zinc sulfide species during roasting of ZnO with pyrite and its contribution on flotation
Authors: Zheng Yong-xing , Lv Jin-fang , Wang Hua , Wen Shu-ming , Pang Jie
Published: May 2018

In this paper, formation of zinc sulfide species during roasting of ZnO with FeS2 was investigated and its contribution on flotation was illustrated. The evolution process, phase and crystal growth were investigated by thermogravimetry (TG), X-Ray diffraction (XRD) along with thermodynamic calculation and scanning electron microscopy-Energy-dispersive X-ray spectroscopy (SEM-EDS), respectively, to interpret the formation mechanism of ZnS species. It was found that ZnS was initially generated at about 450 °C and then the reaction prevailed at about 600 °C. The generated FexS would dissolve into ZnS and then form (Zn, Fe)S compound in form of Fe2Zn3S5 when temperature increased to about 750 °C. This obviously accelerated ZnS phase formation and growth. In addition, it was known that increasing of ZnO dosage had few effects on the decomposition behavior of FeS2. Then, flotation tests of different zinc oxide materials before and after treatment were performed to further confirm that the flotation performances of the treated materials could be obviously improved. Finally, a scheme diagram was proposed to regular its application to mineral processing. It was systematically illustrated that different types of ZnS species needed to be synthetized when sulfidization roasting-flotation process was carried out to treat zinc oxide materials.
A map of the PGC-1α- and NT-PGC-1α-regulated transcriptional network in brown adipose tissue
Authors: Chang Ji Suk , Ghosh Sujoy , Newman Susan , Salbaum J. Michael
Published: May 2018

Transcriptional coactivator PGC-1α and its splice variant NT-PGC-1α play crucial roles in regulating cold-induced thermogenesis in brown adipose tissue (BAT). PGC-1α and NT-PGC-1α are highly induced by cold in BAT and subsequently bind to and coactivate many transcription factors to regulate expression of genes involved in mitochondrial biogenesis, fatty acid oxidation, respiration and thermogenesis. To identify the complete repertoire of PGC-1α and NT-PGC-1α target genes in BAT, we analyzed genome-wide DNA-binding and gene expression profiles. We find that PGC-1α-/NT-PGC-1α binding broadly associates with cold-mediated transcriptional activation. In addition to their known target genes in mitochondrial biogenesis and oxidative metabolism, PGC-1α and NT-PGC-1α additionally target a broad spectrum of genes involved in diverse biological pathways including ubiquitin-dependent protein catabolism, ribonucleoprotein complex biosynthesis, phospholipid biosynthesis, angiogenesis, glycogen metabolism, phosphorylation, and autophagy. Our findings expand the number of genes and biological pathways that may be regulated by PGC-1α and NT-PGC-1α and provide further insight into the transcriptional regulatory network in which PGC-1α and NT-PGC-1α coordinate a comprehensive transcriptional response in BAT in response to cold.
let-7i-5p, miR-181a-2-3p and EGF/PI3K/SOX2 axis coordinate to maintain cancer stem cell population in cervical cancer
Authors: Chhabra Ravindresh
Published: May 2018

The characteristics of cancer stem cells (CSCs) and the genes responsible for their maintenance are highly variable in different cancers. Here, we identify the coordination among miRNAs and EGF pathway genes which is critical for the maintenance of CSCs in cervical cancer. The transcript analysis of CSCs enriched from cervical cancer cell lines (CaSki and HeLa) revealed a significant upregulation of SOX2. Since EGF receptor is frequently over expressed in cervical cancer, we hypothesized that EGF pathway may be responsible for the upregulation of SOX2. Also, the media used for CSC enrichment was supplemented with EGF. The hypothesis was validated as inhibiting the EGF/PI3K pathway suppressed the expression of SOX2 and reduced the CSC population. In addition, miRNA profiling identified miR-181a-2-3p and let-7i-5p as markedly reduced in CSCs. The exogenous expression of either of these miRNAs in CaSki cells inhibited the expression of SOX2 and subsequently reduced CSC population. In conclusion, this study highlights for the first time the contrasting role of let-7i-5p/ miR-181a-2-3p and EGF/PI3K/SOX2 axis in maintaining cervical CSCs. While the EGF pathway promotes CSC formation in cervical cancer by inducing SOX2, miR-181a-2-3p/let-7i-5p counteracts the EGF pathway by inhibiting SOX2, thereby reducing the CSC population.
High electromechanical strain and enhanced temperature characteristics in lead-free (Na,Bi)TiO3–BaTiO3 thin films on Si substrates
Authors: Tanaka Yoshiaki , Okamoto Shoji , Hashimoto Kazuya , Takayama Ryoichi , Harigai Takakiyo , Adachi Hideaki , Fujii Eiji
Published: May 2018

Here, we demonstrate the high electromechanical strain and enhanced temperature characteristics in thec-axis-oriented lead-free (Na,Bi)TiO3–BaTiO3(NBT–BT) polycrystalline thin film prepared on Si substrates by rf magnetron sputtering. The effective transverse piezoelectric coefficient,e31*, estimated from the electromechanical strain measured under high electric field, reaches a high level of −12.5 C/m2, and is comparable to those of conventional Pb(Zr,Ti)O3films.In-situX-ray diffraction measurement and electron diffraction analysis revealed the electromechanical strain of the NBT–BT film to originate predominantly in elongation of the tetragonal (P4bm) crystal lattice in thec-axis direction. In addition to the largee31*, the NBT–BT film exhibits enhanced permittivity maximum temperature,Tm, of ~400 °C and no depolarization belowTm, as compared to bulk NBT–BT havingTm≈ 300 °C and a depolarization temperature of ~100 °C. We conclude that the enhancement of temperature characteristics is associated with the distortedP4bmcrystal lattice formed by deposition-induced stress and defects. We believe that the present study paves the way for practical applications of lead-free piezoelectric thin films in electromechanical devices.
HIV and Vertebral Fractures: a Systematic Review and Metanalysis
Authors: Ilha Thales A. S. H. , Comim Fabio V. , Copes Rafaela M. , Compston Juliet E. , Premaor Melissa O.
Published: May 2018

The survival of HIV-infected patients has increased with the advent of antiretroviral therapy with the emergence of new comorbidities. Vertebral fracture is a manifestation of reduced bone strength and osteoporosis. This study aims to assess the frequency of spine fractures in HIV-positive men and women aged over 18 years. We performed a systematic review of randomized controlled trials, cohort studies, cross-sectional studies, and case-control studies. Studies that evaluated morphometric and/or clinical vertebral fracture were included. In total 488 studies were found, of which 53 had their full texts evaluated. A total of 85,411 HIV positive individuals were identified in 26 studies. The meta-analysis of the prevalence of vertebral fractures included 12 studies with 10,593 subjects. The prevalence was 11.1% [95% confidence interval (95% CI) 4.5%, 25.0%, I2 98.2% p < 0.00001]. When we evaluated independently studies of clinical vertebral fracture and morphometric vertebral fracture, the prevalence was 3.9% (95% CI 0.9, 15.8, I2 96.4% p < 0.00001) and 20.2% (95% CI 15.7%, 25.6%, I2 69.9% p = 0.003) respectively. HIV-infected individuals had an odds ratio of vertebral fractures of 2.3 (95% CI 1.37, 3.85, I2 98.2% p < 0.00001) when compared with HIV-uninfected patients (n = 9 studies). In conclusion, HIV-positive subjects had a higher risk of vertebral fractures when compared with HIV-negative subjects.
Correction: Corrigendum: Association of VAV2 and VAV3 polymorphisms with cardiovascular risk factors
Authors: Perretta-Tejedor Nuria , Fernández-Mateos Javier , García-Ortiz Luis , Gómez-Marcos Manuel A. , Recio-Rodríguez José I. , Agudo-Conde Cristina , Rodriguez-Sánchez Emiliano , Morales Ana I. , López-Hernández Francisco J. , López-Novoa José M. , González-Sarmiento Rogelio , Martínez-Salgado Carlos
Published: May 2018

Scientific Reports 7: Article number: 41875; published online: 03 February 2017; updated: 11 May 2018 This Article contains typographical errors in the Acknowledgements section. “This work was supported by grants from Instituto de Salud Carlos III (Ministry of Economy and Competitiveness, PI12/00959, PI13/01741, RETICS RD012/0005/004 and RD012/0021, co-funded by FEDER) and Junta de Castilla y León (Excellence Group GR100, Ministry of Health, BIO/SA87/13 and IES095U14) and Fundación Mutua Madrileña (IX Call for Grants and Aids for Medical Research).
Erratum: The Dynamics of Coalition Formation on Complex Networks
Authors: Auer S. , Heitzig J. , Kornek U. , Schöll E. , Kurths J.
Published: May 2018

Scientific Reports 5: Article number: 13386; published online: 25 August 2015; updated: 11 May 2018 In the original version of this Article, the Supplementary Information file containing the derivation for individual payoffs was omitted. This error has now been corrected in the PDF and HTML versionsof the Article.
Correction: Corrigendum: Efficient visible-light photocatalytic degradation system assisted by conventional Pd catalysis
Authors: Yu Yanlong , He Tao , Guo Lingju , Yang Yajun , Guo Limei , Tang Yue , Cao Yaan
Published: May 2018

Scientific Reports 5: Article number: 9561; published online: 31 March 2015; updated: 14 May 2018 This Article contains an error. The Authors stated that the cell volume and lattice parameters were derived using Scherrer’s formula. These parameters were actually calculated using Bragg’s law. In the Results section,
Salient space detection algorithm for signal extraction from contaminated and distorted spectrum
Authors: Jia Y. W. , Sun S. Y. , Yang L. , Wang D.
Published: May 2018

The proposed algorithm minimizes the influence of baseline distortion and exhibits good anti-noise ability and high real-time performance.
Negative 2D thermal expansion in the halogen bonded acetone bromine complex
Authors: Marshall W. G. , Jones R. H. , Knight K. S.
Published: May 2018

The complex formed between acetone and bromine shows both negative 2D thermal expansion at low temperature and colossal thermal expansion.
B2O3/SiO2 substitution effect on structure and properties of Na2O–CaO–SrO–P2O5–SiO2 bioactive glasses from molecular dynamics simulations
Authors: Ren Mengguo , Lu Xiaonan , Deng Lu , Kuo Po-Hsuen , Du Jincheng
Published: May 2018

The effect of B2O3/SiO2 substitution in SrO-containing 55S4.3 bioactive glasses on glass structure and properties, such as ionic diffusion and glass transition temperature, was investigated by combining experiments and molecular dynamics simulations with newly developed potentials.
Alkyl chain elongation and acyl group effects in a series of Eu/Tb complexes with hexadentate π-electronic skeletons and their enhanced luminescence in solutions
Authors: Ogata Shuhei , Goto Naoto , Sakurai Shoya , Ishii Ayumi , Hatanaka Miho , Yoshihara Koushi , Tanabe Ryota , Kayano Kyosuke , Magaribuchi Ryo , Goto Kenta , Hasegawa Miki
Published: May 2018

Enhanced luminescence and structural aspects of bpy-based Eu complexes with long alkyl chains and acyl groups were elucidated in solutions.
Elastomeric microvalve geometry affects haemocompatibility
Authors: Szydzik Crispin , Brazilek Rose J. , Khoshmanesh Khashayar , Akbaridoust Farzan , Knoerzer Markus , Thurgood Peter , Muir Ineke , Marusic Ivan , Nandurkar Harshal , Mitchell Arnan , Nesbitt Warwick S.
Published: May 2018

Using a battery of biological and haemodynamic testing we identify a pneumatic microvalve geometry with optimised haemocompatibility.
A magnetic cellulose-based carbon fiber hybrid as a dispersive solid-phase extraction material for the simultaneous detection of six bisphenol analogs from environmental samples
Authors: Zhang Danfeng , Zhang Lei , Liu Tong
Published: May 2018

Hollow porous NiMn2O4 nanosphere-decorated CCFs were used as MDSPE material combined with HPLC for detecting six BPs in environmental samples.
A novel electrochemiluminescence biosensor based on S-doped yttrium oxide ultrathin nanosheets for the detection of anti-Dig antibodies
Authors: Gao Huan , Liu Suli , Wang Zhaoyin , Si Ling , Dai Zhihui
Published: May 2018

The mechanism of a novel electrochemiluminescence biosensor based on S-doped yttrium oxide ultrathin nanosheets for detection of anti-Dig antibodies.
Hydrothermal synthesis of carbon quantum dots as fluorescent probes for the sensitive and rapid detection of picric acid
Authors: Wang Yingte , Chang Xiaoyue , Jing Na , Zhang Yong
Published: May 2018

Carbon dots synthesizedviaa hydrothermal method with a quantum yield of 41.4% are used for the detection of picric acid.
Chemoselective amide reductions by heteroleptic fluoroaryl boron Lewis acids
Authors: Peruzzi Michael T. , Mei Qiong Qiong , Lee Stephen J. , Gagné Michel R.
Published: May 2018

The heteroleptic borane catalyst (C6F5)2B(CH2CH2CH2)BPin is found to hydrosilylatively reduce amides under mild conditions.
Corannulene: a molecular bowl of carbon with multifaceted properties and diverse applications
Authors: Nestoros Eleni , Stuparu Mihaiela C.
Published: May 2018

The chemistry, properties and applications of corannulene are discussed.
Stabilization of organometallic halide perovskite nanocrystals in aqueous solutions and their applications in copper ion detection
Authors: Ma Chunqing , Lo Ming-Fai , Lee Chun-Sing
Published: May 2018

Stabilization of two-dimensional PEA2PbI4 perovskite nanocrystals in water is achieved by controlling the PEA+ concentration.
Role of conformational dynamics in the evolution of novel enzyme function
Authors: Maria-Solano Miguel A. , Serrano-Hervás Eila , Romero-Rivera Adrian , Iglesias-Fernández Javier , Osuna Sílvia
Published: May 2018

Enzymes exist as a dynamic ensemble of conformations, each potentially playing a key role in substrate binding, the chemical transformation, or product release. We discuss recent advances in the evaluation of the enzyme conformational dynamics and its evolution towards new functions or substrate preferences.
An ultrathin photosensitizer for simultaneous fluorescence imaging and photodynamic therapy
Authors: Hu Tongyang , He Jun , Zhang Shaomin , Mei Xuan , Zhang Weiku , Liang Ruizheng , Wei Min , Evans David G. , Duan Xue
Published: May 2018

An ultrathin photosensitizer was prepared by immobilization of chlorin e6 (Ce6) and carbon dots (CDs) onto layered double hydroxide (LDH) nanosheets, which exhibited excellent fluorescence imaging and photodynamic therapy performance toward cancer theranostics.
Carbene-catalyzed enal γ-carbon addition to α-ketophosphonates for enantioselective access to bioactive 2-pyranylphosphonates
Authors: Sun Jun , He Fangcheng , Wang Zhongyao , Pan Dingwu , Zheng Pengcheng , Mou Chengli , Jin Zhichao , Chi Yonggui Robin
Published: May 2018

A carbene-catalyzed [4+2] reaction of enals and α-ketophosphonates is developed to afford chiral 2-pyranylphosphonates with potential use in plant protection.
Photocatalytic difunctionalisations of alkenes with N-SCN sulfoximines
Authors: Zhang Duo , Wang Han , Bolm Carsten
Published: May 2018

Reacting N-Br sulfoximines with ammonium thiocyanate leads to unprecedented sulfur reagents, which add to vinyl arenes under photocatalysis via N-centered sulfoximidoyl radicals.
High-throughput screening of solid-state catalysts for nerve agent degradation
Authors: Palomba Joseph M. , Credille Cy V. , Kalaj Mark , DeCoste Jared B. , Peterson Gregory W. , Tovar Trenton M. , Cohen Seth M.
Published: May 2018

A high-throughput screening (HTS) method was devised to increase the rate of discovery and evaluation of nerve agent degradation catalysts.
Transition metal-free one-pot double C–H functionalization of quinolines with disubstituted electron-deficient acetylenes
Authors: Trofimov B. A. , Belyaeva K. V. , Nikitina L. P. , Mal'kina A. G. , Afonin A. V. , Ushakov I. A. , Vashchenko A. V.
Published: May 2018

Metal-free reaction between quinolines, aryltrifluoroacetylacetylenes and water resulted in stereoselective assembly of trifluoromethylated oxazinoquinolines in up to 99% yield.
Homolytic cleavage of peroxide bonds via a single electron transfer of a frustrated Lewis pair
Authors: Liu Liu Leo , Cao Levy L. , Zhu Diya , Zhou Jiliang , Stephan Douglas W.
Published: May 2018

Single electron transfer (SET) reactions are effected by the combination of a Mes3P/B(C6F5)3 frustrated Lewis pair with benzoyl peroxide derivatives.
Synthesis, crystal structures and magnetic properties of six coordination compounds constructed with pyridine iminomethyl–TEMPO radicals and [M(hfac)2] (M = CuII and MnII)
Authors: Gao Yan-Li , Nishihara Sadafumi , Inoue Katsuya
Published: May 2018

We describe the crystal structures and magnetic properties of six coordination metal-(R-Py-iminomethyl-TEMPO) radical compounds.
Phase-controlled synthesis and the phase-dependent HER and OER performances of nickel selenide nanosheets prepared by an electrochemical deposition route
Authors: Zhu Jiawei , Ni Yonghong
Published: May 2018

Phase-controlled synthesis of nickel selenide nanostructures was successfully realized via a facile electrodeposition route with the same electrolyte at room temperature.
Identification of the cubic-to-hexagonal phase transition for the production of stable zinc oxynitride layers
Authors: Gómez-Castaño M. , Pau J. L. , Redondo-Cubero A.
Published: May 2018

The control of the crystalline phases in zinc oxynitride layers can help to developing more stable thin film transistors.
Curcumin: pharmaceutical solids as a platform to improve solubility and bioavailability
Authors: Suresh Kuthuru , Nangia Ashwini
Published: May 2018

The remarkable improvements in the pharmacokinetics and high bioavailability of curcumin polymorphs, amorphous, cocrystals, eutectics, and coamorphous solids are discussed. The importance of pharmaceutical solids in the advanced formulation development of herbal and bioactive molecule curcumin is presented.
The influence of acceptor and donor doping on the protonic surface conduction of TiO2
Authors: Stub Sindre Østby , Thorshaug Knut , Rørvik Per Martin , Norby Truls , Vøllestad Einar
Published: May 2018

Surface protonic transport in porous oxides is important for many catalytic and electrochemical applications and is altered by changing the acid–base properties of the oxide surface through aliovalent doping.
The last link of the x-aminobutyric acid series: the five conformers of β-aminobutyric acid
Authors: León I. , Peña I. , Cabezas C. , Alonso E. R. , Alonso J. L.
Published: May 2018

Structural characterization of β-aminobutyric acid by rotational spectroscopy.
Substituent effect on the dynamics of the inclusion complex formation between protoberberine alkaloids and cucurbit[7]uril
Authors: Miskolczy Zsombor , Biczók László , Lendvay György
Published: May 2018

The dynamics and activation parameters of alkaloid entry into and exit from cucurbit[7]uril significantly depend on the substitution pattern.
Dynamical crossover of water confined within the amphiphilic nanocores of aggregated amyloid β peptides
Authors: Khatua Prabir , Bandyopadhyay Sanjoy
Published: May 2018

The size-dependent structural crossover of Aβ protofilaments at the decamer is associated with correlated dynamical transition of water confined within its amphiphilic core.
How big is the substituent dependence of the solar photolysis rate of Criegee intermediates?
Authors: Yin Cangtao , Takahashi Kaito
Published: May 2018

Substituent dependence of the UV spectra of Criegee intermediates were calculated using multireference methods.
Intermediate length-scale chirality related to the vibrational circular dichroism intensity enhancement upon fibril formation in a gelation process
Authors: Torii Hajime , Sato Hisako
Published: May 2018

The VCD intensity enhancement occurring upon fibril formation arises from the second out of the three hierarchical tiers of chirality.
Oxidative dehydrogenation of propane over Pt–Sn/Si-beta catalysts: key role of Pt–Sn interaction
Authors: Sun Lanlan , Chai Yuchao , Dai Weili , Wu Guangjun , Guan Naijia , Li Landong
Published: May 2018

Bimetallic Pt–Sn catalysts supported on dealuminated Si-beta zeolite were preparedviawet impregnation and the nanoscale close contact between Pt and Sn species in Pt–Sn/Si-beta was confirmed by electron microscopy analyses.
Characterization of nano-porosity in molecular layer deposited films
Authors: Perrotta Alberto , Poodt Paul , van den Bruele F. J. (Fieke) , Kessels W. M. M. (Erwin) , Creatore Mariadriana
Published: May 2018

A correlation was found between the MLD process conditions, the open-porosity relative content, and the degradation of metalcone layers.
A sea-change: manganese doped nickel/nickel oxide electrocatalysts for hydrogen generation from seawater
Authors: Lu Xunyu , Pan Jian , Lovell Emma , Tan Tze Hao , Ng Yun Hau , Amal Rose
Published: May 2018

The facile and scalable synthesis of manganese-doped nickel/nickel oxide heterostructures with high activity, outperforming the Pt benchmark, in neutral electrolytes.
Supported cluster catalysts synthesized to be small, simple, selective, and stable
Authors: Guan Erjia , Fang Chia-Yu , Yang Dong , Wang Liang , Xiao Feng-Shou , Gates Bruce C.
Published: May 2018

Molecular metal complexes on supports have drawn wide attention as catalysts offering new properties and opportunities for precise synthesis to make uniform catalytic species that can be understood in depth.
Phase-shift feedback control for dielectrophoretic micromanipulation
Authors: Zemánek Jiří , Michálek Tomáš , Hurák Zdeněk
Published: May 2018

A versatile electrode array and the control system for noncontact micromanipulation of several objects using dielectrophoresis (DEP).
iPhone-imaged and cell-powered electrophoresis titration chip for the alkaline phosphatase assay in serum by the moving reaction boundary
Authors: Cao Xin-yu , Kong Fan-zhi , Zhang Qiang , Liu Wei-wen , Liu Xiao-ping , Li Guo-qing , Zhong Ran , Fan Liu-yin , Xiao Hua , Cao Cheng-xi
Published: May 2018

A portable, simple and low-cost ALP-ET chip based on moving reaction boundary was developed for fast and sensitive ALP detection.
Selenium species-dependent toxicity, bioavailability and metabolic transformations inCaenorhabditis elegans
Authors: Rohn Isabelle , Marschall Talke Anu , Kroepfl Nina , Jensen Kenneth Bendix , Aschner Michael , Tuck Simon , Kuehnelt Doris , Schwerdtle Tanja , Bornhorst Julia
Published: May 2018

Depending strongly on the ingested selenium (Se) form differences in toxicity, bioavailability as well as metabolism occur inC. elegans.
Preparation and characterization of molecularly imprinted solid amine adsorbent for CO2adsorption
Authors: Liu Fenglei , Kuang Yizhu , Wang Shuoyu , Chen Shuixia , Fu Wenhao
Published: May 2018

A molecularly imprinted solid amine adsorbent was successfully synthesized and exhibited excellent CO2adsorption performance under simulated flue gas.
Novel formation of Bi@BiFe-glycolate hollow spheres and their conversion into Bi2O3/BiFeO3 composite hollow spheres with enhanced activity and durability in visible photocatalysis
Authors: Yang Xu , Meng Junsheng , Wang Yu , Meng Qingqiang , Hu Yongyuan , Di Andi , Wu Yuehan , Chen Gang
Published: May 2018

Novel passion fruit-like Bi@BiFe-glycolate hollow spheres are synthesized and explained by an interesting mechanism of “spit and swallow” process.
Aerobic oxidative esterification and thioesterification of aldehydes using dibromoisocyanuric acid under mild conditions: no metal catalysts required
Authors: Kwon Young-Do , La Minh Thanh , Kim Hee-Kwon
Published: May 2018

Esters and thioesters were successfully prepared through oxidative esterification and thioesterification of corresponding aldehydes in the presence of dibromoisocyanuric acid.
Photochromic thermoplastics doped with nanostructured tungsten trioxide
Authors: Li Naixu , Huo Mengmeng , Li Min , Li Tuoqi , Zhou Jiancheng , Zhang Jiuyang
Published: May 2018

Photochromic materials were successfully fabricated by blending WO3 nanocrystals with different morphologies (nanosheet, nanorod, and amorphous) into a polymer matrix.
Preconcentration and ultra-trace determination of hexavalent chromium ions using tailor-made polymer nanoparticles coupled with graphite furnace atomic absorption spectrometry: ultrasonic assisted-dispersive solid-phase extraction
Authors: Parvizi Samira , Behbahani Mohammad , zeraatpisheh Fatemeh , Esrafili Ali
Published: May 2018

We describe ultrasonic assisted-dispersive solid-phase extraction based on tailor-made polymer (UA-DSPE-TMP) nanoparticles for selective extraction of Cr(vi) ions.
Two stereocentered HKR of anti-β,β′-diphenylpropanoxirane and anti-3-phenylethyloxiranes catalysed by Co(iii)(salen)-OAc complex: enantioselective synthesis of (+)-sertraline and (+)-naproxen
Authors: Kamble Rohit B. , Devalankar Dattatraya , Suryavanshi Gurunath
Published: May 2018

Two stereocentered HKR of anti-β,β′-diphenylmethyloxirane and anti-3-phenylethyloxiranes gives enantiopure anti-1,2-diols and oxiranes. This method is utilised for the synthesis of (+)-sertraline and (+)-naproxen.
Structural features, magnetic properties and photocatalytic activity of bismuth ferrite nanoparticles grafted on graphene nanosheets
Authors: Bajpai Om Prakash , Mandal Subrata , Ananthakrishnan Rajakumar , Mandal Pijush , Khastgir Dipak , Chattopadhyay Santanu
Published: May 2018

Bismuth ferrite grafted on graphene nanosheets (BiFeO3-g-GNS) works as an efficient photocatalyst for organic pollutants/dyes, irrespective of the ionic nature of the pollutants.
Nanoparticle-enhanced electrical detection of Zika virus on paper microchips
Authors: Draz Mohamed Shehata , Venkataramani Manasa , Lakshminarayanan Harini , Saygili Ecem , Moazeni Maryam , Vasan Anish , Li Yudong , Sun Xiaoming , Hua Stephane , Yu Xu G. , Shafiee Hadi
Published: May 2018

Zika virus (ZIKV) is a reemerging flavivirus causing an ongoing pandemic and public health emergency worldwide. We developed nanoparticle-enhanced sensing of virus lysate for electrical detection of ZIKV on paper microchip.
Streamlined chemoenzymatic total synthesis of prioritized ganglioside cancer antigens
Authors: Yu Hai , Santra Abhishek , Li Yanhong , McArthur John B. , Ghosh Tamashree , Yang Xiaoxiao , Wang Peng G. , Chen Xi
Published: May 2018

Highly efficient streamlined total synthesis of complex prioritized gangliosides was achieved chemoenzymatically by sequential one-pot multienzyme (OPME) reactions with facile C18 cartridge purification schemes followed by high-yield acylation.
UV-triggered shape-controllable PP fabric
Authors: Shang Jiaojiao , Lin Shaojian , Theato Patrick
Published: May 2018

A light-driven polypropylene (PP) fabric as an actuator was fabricated in which a light-responsive polymeric film acts as an active layer and a PP fabric acts as a passive layer.
Mo-Triggered amorphous Ni3S2 nanosheets as efficient and durable electrocatalysts for water splitting
Authors: Zhang Haoxuan , Jiang Hao , Hu Yanjie , Saha Petr , Li Chunzhong
Published: May 2018

A Mo-triggered amorphous Ni3S2 electrocatalyst greatly enhances adsorption of HER targeted intermediates without sacrificing its excellent OER activity for water splitting.
Convergent syntheses of 2,3-dihydrobenzofurans via a Catellani strategy
Authors: Wu Chenggui , Cheng Hong-Gang , Chen Ruiming , Chen Han , Liu Ze-Shui , Zhang Jingyang , Zhang Yuming , Zhu Yuxin , Geng Zhi , Zhou Qianghui
Published: May 2018

The annulation of aryl iodides and epoxides to convergently access valuable 2,3-dihydrobenzofuran scaffolds was developed via a Catellani strategy.
Insights into the NHC-catalyzed cascade Michael/aldol/lactamization reaction: mechanism and origin of stereoselectivity
Authors: Wang Yang , Zhang Shou-Ren , Wang Yanyan , Qu Ling-Bo , Wei Donghui
Published: May 2018

A DFT study of the NHC-catalyzed cascade Michael/aldol/lactamization reaction has been performed for the first time.
Toward simultaneous toughening and reinforcing of trifunctional epoxies by low loading flexible reactive triblock copolymers
Authors: Tang Bing , Kong Miqiu , Yang Qi , Huang Yajiang , Li Guangxian
Published: May 2018

A high performance trifunctional epoxy thermoset was toughened and reinforced by a low loading of GPG with an appropriate reactive block length, which presented a homogeneous morphology.
An inflammatory memory and angiogenic self-assembling nanofiber hydrogel scaffold seeded withAkkermansia muciniphilato accelerate the healing of diabetic ischemic ulcers
Authors: Cheng Panke , Yao Liyang , Chen Xiaolong , Su Xingxing , Su Xuejiao , Huang Qiang , Hou Chunli
Published: May 2018

In this research, a polypeptide skeleton was synthesized based on 3,4-dihydroxyphenylalanine (DOPA) and conjugated with inflammatory and angiogenesis peptides, combined withA. Muciniphilaas a novel strategy for diabetic ischemic ulcer treatment.
An eccentric rod-like linear connection of two heterocycles: synthesis of pyridine trans-tetrafluoro-λ6-sulfanyl triazoles
Authors: Das Prajwalita , Niina Kiyoteru , Hiromura Tomoya , Tokunaga Etsuko , Saito Norimichi , Shibata Norio
Published: May 2018

An eccentric trans-SF4 unit achieves a rod-like linear connection of two independent N-heterocycles, pyridines and triazoles.
Pyrene hydrogel for promoting direct bioelectrochemistry: ATP-independent electroenzymatic reduction of N2
Authors: Hickey David P. , Lim Koun , Cai Rong , Patterson Ashlea R. , Yuan Mengwei , Sahin Selmihan , Abdellaoui Sofiene , Minteer Shelley D.
Published: May 2018

We demonstrate a novel hydrogel material to facilitate direct bioelectrochemistry of a wide range of redox proteins and enable ATP-independent electroenzymatic reduction of N2 by nitrogenase.
Infiltrated mesoporous oxygen electrodes for high temperature co-electrolysis of H2O and CO2 in solid oxide electrolysis cells
Authors: Hernández E. , Baiutti F. , Morata A. , Torrell M. , Tarancón A.
Published: May 2018

In the last years high temperature Solid Oxide Electrolysis Cells (SOECs) have emerged as a promising solution for energy conversion and storage. Oxygen electrodes based on mesoporous materials are proposed for enhancing the performance and durability of SOEC devices.
SnP nanocrystals as anode materials for Na-ion batteries
Authors: Liu Junfeng , Wang Shutao , Kravchyk Kostiantyn , Ibáñez Maria , Krumeich Frank , Widmer Roland , Nasiou Déspina , Meyns Michaela , Llorca Jordi , Arbiol Jordi , Kovalenko Maksym V. , Cabot Andreu
Published: May 2018

Sodium ion batteries based on SnP NCs and sodium(i) bis(fluorosulfonyl)imide electrolyte displayed high reversible capacities and cycling stability.
The use of metal–organic frameworks for CO purification
Authors: Evans Arwyn , Luebke Ryan , Petit Camille
Published: May 2018

Metal organic frameworks (MOFs) as adsorbents present a potentially cost effective and energy saving alternative to current technologies used to purify carbon monoxide (CO), a reagent in numerous industrial processes. This review compares the different mechanisms involved in CO adsorption in MOFs, highlighting the desired chemical and structural features for this process. An outlook on future directions for research on MOFs for CO adsorption is proposed.
Diffusion of Li-deficient phases in large LiFePO4 single crystals during chemical delithiation
Authors: Yamanaka Toshiro , Abe Takeshi , Nishio Koji , Ogumi Zempachi
Published: May 2018

Unexpectedly fast diffusion of microphases with Li-vacancies through large LiFePO4 single crystals was detected by Raman spectroscopy.
Hydrogen plasma reduced potassium titanate as a high power and ultralong lifespan anode material for sodium-ion batteries
Authors: Yang Ze , Sun Jingying , Xie Yunlong , Kaur Pawanjit , Hernandez Joseph , Ni Yizhou , Yu Ying , Varghese Oomman K. , Huang Yunhui , Chen Shuo
Published: May 2018

The abundance and low cost of sodium potentially enable application of sodium ion batteries for grid-scale energy storage.
A general synthetic approach for hexagonal phase tungsten nitride composites and their application in the hydrogen evolution reaction
Authors: Jin Haiyan , Zhang Hao , Chen Jiayi , Mao Shanjun , Jiang Zheng , Wang Yong
Published: May 2018

Metallic Co promoted the phase transformation of β-WN to δ-WN. δ-WN exhibited superior HER performance compared to β-WN.
Metal–organic framework derived Co3O4/C@SiO2 yolk–shell nanoreactors with enhanced catalytic performance
Authors: Zhang Ming , Wang Chaohai , Liu Chao , Luo Rui , Li Jiansheng , Sun Xiuyun , Shen Jinyou , Han Weiqin , Wang Lianjun
Published: May 2018

The possible synergistic mechanisms of BPA degradation on YSCCSs.
A substrate-independent ultrathin hydrogel film as an antifouling and antibacterial layer for a microfiltration membrane anchored via a layer-by-layer thiol–ene click reaction
Authors: He Min , Wang Qian , Zhao Weifeng , Zhao Changsheng
Published: May 2018

A hydrogel film was attached to a membrane surface to confer it with antifouling and antibacterial properties without compromising its permeability.
Formation mechanism of 2D SnS2 and SnS by chemical vapor deposition using SnCl4 and H2S
Authors: Zhang Haodong , Balaji Yashwanth , Nalin Mehta Ankit , Heyns Marc , Caymax Matty , Radu Iuliana , Vandervorst Wilfried , Delabie Annelies
Published: May 2018

Catalytic decomposition of H2S by SnS2, with generation of H2, plays a critical role in the SnCl4/H2S CVD process.
Anthracene-based semiconductors for organic field-effect transistors
Authors: Chen Mengyun , Yan Lijia , Zhao Yang , Murtaza Imran , Meng Hong , Huang Wei
Published: May 2018

A review of materials design strategies and efficient study methods for modeling of anthracene derivatives, with a description of their significant application in light-emitting transistors.
Structural and ligand-binding analysis of the YAP-binding domain of transcription factor TEAD4
Authors: Li Yan , Liu Shuang , Ng Elizabeth Yihui , Li Rong , Poulsen Anders , Hill Jeffrey , Pobbati Ajaybabu V. , Hung Alvin W. , Hong Wanjin , Keller Thomas H. , Kang CongBao
Published: May 2018

The oncoprotein YAP (Yes-associated protein) requires the TEAD family of transcription factors for the up-regulation of genes important for cell proliferation. Disrupting YAP–TEAD interaction is an attractive strategy for cancer therapy. Targeting TEADs using small molecules that either bind to the YAP-binding pocket or the palmitate-binding pocket is proposed to disrupt the YAP–TEAD interaction. There is a need for methodologies to facilitate robust and reliable identification of compounds that occupy either YAP-binding pocket or palmitate-binding pocket. Here, using NMR spectroscopy, we validated compounds that bind to these pockets and also identify the residues in mouse TEAD4 (mTEAD4) that interact with these compounds. Flufenamic acid (FA) was used as a positive control for validation of palmitate-binding pocket-occupying compounds by NMR. Furthermore, we identify a hit from a fragment screen and show that it occupies a site close to YAP-binding pocket on the TEAD surface. Our results also indicate that purified mTEAD4 can catalyze autopalmitoylation. NMR studies on mTEAD4 revealed that exchanges exist in TEAD as NMR signal broadening was observed for residues close to the palmitoylation site. Mutating the palmitoylated cysteine (C360S mutant) abolished palmitoylation, while no significant changes in the NMR spectrum were observed for the mutant which still binds to YAP. We also show that FA inhibits TEAD autopalmitoylation. Our studies highlight the utility of NMR spectroscopy in identifying small molecules that bind to TEAD pockets and reinforce the notion that both palmitate-binding pocket and YAP-binding pocket are targetable.
Perturbations in mitochondrial dynamics by p66Shc lead to renal tubular oxidative injury in human diabetic nephropathy
Authors: Zhan Ming , Usman Irtaza , Yu Jingbo , Ruan Liemin , Bian Xueyan , Yang Jun , Yang Shikun , Sun Lin , Kanwar Yashpal S.
Published: May 2018

Renal tubular injury is increasingly being recognized as an early characteristic of diabetic nephropathy (DN). Mitochondrial dynamic alterations and redox protein p66Shc-mediated oxidative stress are both critical for ensuing diabetic tubular cell injury and apoptosis; whether these two processes are interlinked remains unclear. In the present study, we observed changes in mitochondrial morphology and expression of associated proteins in tubules of patients with DN. We demonstrated mitochondrial fragmentation as an important pathogenic feature of tubular cell injury that is linked to oxidative stress and p66Shc up-regulation. In renal proximal tubular cells, alterations in mitochondrial dynamics and expression of fission–fusion proteins were observed under high glucose (HG) ambience, along with p66Shc Ser36 phosphorylation. Gene ablation of p66Shc alleviated HG-induced mitochondrial fragmentation, down-regulated Fis1 and reduced p66Shc–Fis1 binding, increased Mfn1 expression, and disrupted interactions between Mfn1 and proapoptotic Bak. Overexpression of p66Shc exacerbated these changes, whereas overexpression of dominant-negative p66Shc Ser36 mutant had a marginal effect under HG, indicating that p66Shc phosphorylation as a prerequisite in the modulation of mitochondrial dynamics. Disrupted mitochondrial dynamics and enhanced Mfn1–Bak interactions modulated by p66Shc led to loss of mitochondrial voltage potential, cytochrome C release, excessive ROS generation, and apoptosis. Taken together, these results link p66Shc to mitochondrial dynamic alterations in the pathogenesis of DN and unveil a novel mechanism by which p66Shc mediates HG-induced mitochondrial fragmentation and proapoptotic signaling that results in oxidative injury and apoptosis in the tubular compartment in human diabetic nephropathy.
Red supergiant stars in the Large Magellanic Cloud
Authors: Yang Ming , Bonanos Alceste Z. , Jiang Bi-Wei , Gao Jian , Xue Meng-Yao , Wang Shu , Lam Man I , Spetsieri Zoi T. , Ren Yi , Gavras Panagiotis
Published: May 2018

The characteristics of infrared properties and mid-infrared (MIR) variability of red supergiant (RSG) stars in the Large Magellanic Cloud (LMC) are analyzed based on 12 bands of near-infrared (NIR) to MIR co-added data from 2MASS, Spitzer and WISE, and ∼6.6 yr of MIR time-series data collected by the ALLWISE and NEOWISE-R projects. 773 RSGs candidates were compiled from the literature and verified by using the color-magnitude diagram (CMD), spectral energy distribution (SED) and MIR variability. About 15% of valid targets in the IRAC1–IRAC2/IRAC2–IRAC3 diagram may show polycyclic aromatic hydrocarbon (PAH) emission. We show that arbitrary dereddening Q parameters related to the IRAC4, S9W, WISE3, WISE4, and MIPS24 bands could be constructed based on a precise measurement of MIR interstellar extinction law. Several peculiar outliers in our sample are discussed, in which one outlier might be a RSG right before the explosion or an extreme asymptotic giant branch (AGB) star in the very late evolutionary stage based on the MIR spectrum and photometry. There are 744 identified RSGs in the final sample having both the WISE1- and WISE2-band time-series data. The results show that the MIR variability is increasing along with the increasing of brightness. There is a relatively tight correlation between the MIR variability, mass loss rate (MLR; in terms of KS–WISE3 color), and the warm dust or continuum (in terms of WISE4 magnitude/flux), where the MIR variability is evident for the targets with KS–WISE3 > 1.0 mag and WISE4 < 6.5 mag, while the rest of the targets show much smaller MIR variability. The MIR variability is also correlated with the MLR for which targets with larger variability also show larger MLR with an approximate upper limit of −6.1 M⊙ yr−1. Both the variability and the luminosity may be important for the MLR since the WISE4-band flux is increasing exponentially along with the degeneracy of luminosity and variability. The identified RSG sample has been compared with the theoretical evolutionary models and shown that the discrepancy between observation and evolutionary models can be mitigated by considering both variability and extinction.
Gone with the wind: the impact of wind mass transfer on the orbital evolution of AGB binary systems
Authors: Saladino M. I. , Pols O. R. , van der Helm E. , Pelupessy I. , Portegies Zwart S.
Published: May 2018

In low-mass binary systems, mass transfer is likely to occur via a slow and dense stellar wind when one of the stars is in the asymptotic giant branch (AGB) phase. Observations show that many binaries that have undergone AGB mass transfer have orbital periods of 1–10 yr, at odds with the predictions of binary population synthesis models. In this paper we investigate the mass-accretion efficiency and angular-momentum loss via wind mass transfer in AGB binary systems and we use these quantities to predict the evolution of the orbit. To do so, we perform 3D hydrodynamical simulations of the stellar wind lost by an AGB star in the time-dependent gravitational potential of a binary system, using the AMUSE framework. We approximate the thermal evolution of the gas by imposing a simple effective cooling balance and we vary the orbital separation and the velocity of the stellar wind. We find that for wind velocities higher than the relative orbital velocity of the system the flow is described by the Bondi-Hoyle-Lyttleton approximation and the angular-momentum loss is modest, which leads to an expansion of the orbit. On the other hand, for low wind velocities an accretion disk is formed around the companion and the accretion efficiency as well as the angular-momentum loss are enhanced, implying that the orbit will shrink. We find that the transfer of angular momentum from the binary orbit to the outflowing gas occurs within a few orbital separations from the centre of mass of the binary. Our results suggest that the orbital evolution of AGB binaries can be predicted as a function of the ratio of the terminal wind velocity to the relative orbital velocity of the system, v∞/vorb. Our results can provide insight into the puzzling orbital periods of post-AGB binaries. The results also suggest that the number of stars entering into the common-envelope phase will increase, which can have significant implications for the expected formation rates of the end products of low-mass binary evolution, such as cataclysmic binaries, type Ia supernovae, and double white-dwarf mergers.
Die Bedeutung des MRT nach geschlossener Reposition der traumatischen Hüftgelenkluxation im Kindes- und Jugendalter
Authors: Strüwind Christoph , von Rüden Christian , Thannheimer Andreas , Bühren Volker , Schneidmueller Dorien
Published: May 2018

Hintergrund Die traumatische Hüftgelenkluxation im Kindes- und Jugendalter stellt eine Rarität da. Verletzungsmechanismus ist i. d. R. ein Hochrasanztrauma. Nach geschlossener Reposition hängt die weitere Behandlung vom genauen Verletzungsmuster ab, das sich mittels Schnittbilddiagnostik darstellen lässt. Ziel dieser retrospektiven Untersuchung war es, die Häufigkeit von relevanten Begleitverletzungen nach traumatischer Hüftgelenkluxation bei Kindern und Jugendlichen zu erfassen und die Notwendigkeit einer gezielten Diagnostik zu überprüfen.

Patienten/Material und Methoden In diese retrospektive Fallserie wurden 8 Patienten im Alter unter 18 Jahren mit einer isolierten Hüftgelenkluxation ohne Azetabulumfraktur zwischen 2001 und 2017 erfasst, die noch am Unfalltag notfallmäßig in Kurznarkose geschlossen reponiert wurden. In 5 Fällen wurde nach Reposition ein Magnetresonanztomogramm (MRT) und in 3 Fällen ein Computertomogramm (CT) zur diagnostischen Bilanzierung des Verletzungsausmaßes durchgeführt.

Ergebnisse Zwei Mädchen und 6 Jungen mit einem Durchschnittsalter von 11 (5 – 16) Jahren konnten eingeschlossen werden. Bei 2 Patienten ergab sich nach geschlossener Reposition im CT ein freier knöcherner Gelenkkörper im dorsalen Gelenkspalt. Intraoperativ zeigte sich in beiden Fällen zusätzlich eine Interposition des Labrums in den Gelenkspalt. Bei einem Patienten, bei dem nach geschlossener Reposition ein MRT durchgeführt wurde, war das Labrum in den Gelenkspalt interponiert. Intraoperativ bestätigte sich der MRT-Befund. Bei 4 weiteren Patienten zeigte sich im MRT nach geschlossener Reposition keine Labrumverletzung. Als weitere Begleitverletzungen wurden ein Abriss der Spina iliaca anterior inferior sowie eine Ruptur des Lig. capitis femoris beschrieben.

Schlussfolgerung Das MRT nach traumatischen Hüftgelenkluxationen im Kindes- und Jugendalter gewinnt zunehmend an Bedeutung. Das Fehlen eines chondralen oder osteochondralen Fragments im CT schließt eine Verletzung oder Interposition des Labrums nicht aus. Basierend auf den Ergebnissen dieser Untersuchung wird daher das MRT möglichst zeitnah nach geschlossener Reposition einer traumatischen Hüftgelenkluxation grundsätzlich empfohlen.
Synthesis and in vitro Evaluation of 2-heteroarylidene-1-tetralone Derivatives as Monoamine Oxidase Inhibitors
Authors: Amakali Klaudia , Legoabe Lesetja , Petzer Anél , Petzer Jacobus
Published: May 2018

The present study investigates the human monoamine oxidase (MAO) inhibition properties of a series of twelve 2-heteroarylidene-1-tetralone derivatives. Also included are related cyclohexylmethylidene, cyclopentylmethylidene and benzylidene substituted 1-tetralones. These compounds are related to the 2-benzylidene-1-indanone class of compounds which has previously been shown to inhibit the MAOs, with specificity for the MAO-B isoform. The target compounds were synthesised by the Claisen-Schmidt condensation between 7-methoxy-1-tetralone or 1-tetralone, and various aldehydes, under acid (hydrochloric acid) or base (potassium hydroxide) catalysis. The results of the MAO inhibition studies showed that the 2-heteroarylidene-1-tetralone and related derivatives are in most instances more selective inhibitors of the MAO-B isoform compared to MAO-A. (2E)-2-Benzylidene-7-methoxy-3,4-dihydronaphthalen-1(2 H)-one (IC50=0.707 μM) was found to be the most potent MAO-B inhibitor, while the most potent MAO-A inhibitor was (2E)-2-[(2-chloropyridin-3-yl)methylidene]-7-methoxy-3,4-dihydronaphthalen-1(2 H)-one (IC50=1.37 μM). The effect of the heteroaromatic substituent on MAO-B inhibition activity, in decreasing order was found to be: cyclohexyl, phenyl>thiophene>pyridine, furane, pyrrole, cyclopentyl. This study concludes that, although some 2-heteroarylidene-1-tetralone derivatives are good potency MAO inhibitors, in general their inhibition potencies, particularly for MAO-B, are lower than structurally related chalcones and 1-indanone derivatives that were previously studied.