bluuebunny/crossref_metadata_2025 huggingface dataset:
Dominant Personality of Otto in A Man Called Otto Movie
Authors: Azizah Miftahatul Lu'lu' , Hawasi Hawasi
Published: January 2024

Personality is an important component in character development in a movie. Each character has a dominant personality that differentiate one character from another which influences how each character feels, thinks, and behaves. The problems in this research are what are Otto’s personality traits and what is Otto’s dominant personality in A Man Called Otto movie based on Florence Littauer’s theory and how does the dominant personality influence Otto in A Man Called Otto movie. The objectives in this research are to find out Otto’s personality traits and Otto’s dominant personality in A Man Called Otto movie based on Florence Littauer’s theory and to explain the influence of dominant personality on Otto in A Man Called Otto movie. The researcher used a qualitative method and the data were collected from the scenes and the dialogues. After analyzing the data, the researcher found 6 traits for Sanguine, 10 traits for Melancholy, 22 traits for Choleric, and 2 traits for Phlegmatic. The researcher found the dominant type of Otto’s personality is Choleric. Choleric personality influences how Otto feels, thinks, and behaves in his daily activities.
Gangguan Kesehatan pada Masyarakat yang Disebabkan oleh Bakteri Mesofilik
Authors: Gemilang Putra Satria
Published: January 2024

Banyak kejadian-kejadian atau berita-berita tentang kesehatan yang ada di mediacetak maupun elektronik diberitakan di Indonesia. Jika dicermati beberapa penyakityang terjadi itu disebabkan oleh bakteri mesofilik. Bakteri mesofilik adalah bakteriyang cocok di iklim tropis. Namun beberapa bakteri ini adalah patogen yang artinyabakteri ini menyebabkan penyakit jika masuk ke dalam tubuh manusia. Karenasebab itu harus menjadi perhatian yang serius sebab Indonesia berada di gariskhatulistiwa artinya Indonesia beriklim tropis hal ini yang menyebabkan akanbanyak bakteri mesofilik yang akan tumbuh dan menginfeksi manusia. Padaumumnya suhu udara sekitar 20-30 oC. Bahkan bisa mencapai lebih dari 30oC dibeberapa tempat. Juga mungkin ada beberapa hal yang turut serta mendukungtumbuh kembangnya bakteri mesofilik. Metode yang digunakan adalah kajiankepustakaan dengan pendekatan deskriptif dan eksploratif dari hasil penelitianterdahulu. Hasil penelitian menunjukan bahwa: (1) Beberapa penyakit yangditimbulkan dari bakteri mesofilik terdapat pada bagian pencernaan, pernapasan,dan kulit (2) Bakteri mesofilik mengeluarkan toksin (3) Infeksi yang ditimbulkanoleh bakteri mesofilik menimbulkan gejala-gejala klinis.
Sistem Pendukung Keputusan Distribusi Penanganan Perkara Keberatan Pada Direktorat Jenderal Pajak Dengan Metode SAW
Authors: Panggabean Marcelina , Wibawanti Yuni , Mustika Fanisya Alva
Published: January 2024

Direktorat Jenderal Pajak (DJP) adalah instansi yang diberi amanat oleh Undang- Undang untuk menyelenggarakan salah satu fungsi pelaksanaan administrasi perpajakan yaitu penanganan perkara keberatan yang diajukan Wajib Pajak atas ketetapan yang diterbitkan. Perkara keberatan ditangani oleh pegawai dengan jabatan Penelaah Keberatan. Dalam pelaksanaanya, penentuan Penelaah Keberatan masih dilakukan secara manual tanpa melihat kompetensi dan beban kerja dari penelaah keberatan. Hal ini dikarenakan belum tersedianya secara sistem informasi kompetensi dan beban kerja dari Penelaah Keberatan. Salah satu solusi pemecahan masalah tersebut adalah dengan merancang sistem pendukung keputusan penentuan PK untuk menangani perkara keberatan dengan metode Simple Additive Weighting (SAW). Dengan adanya sistem pendukung keputusan ini Kepala Seksi Kepala Seksi Keberatan, Banding dan Pengurangan (KBP) mampu menentukan pilihan terbaik untuk penugasan penanganan perkara keberatan berdasarkan risiko perkara, kompetensi, pengalaman dan beban kerja PK.
Penerapan Mobile UI Flutter Untuk Membangun Aplikasi Pariwisata Kota Pacitan Berbasis Android
Authors: Prasetyo Ribut Dwi , Husain Ahmad , Puspitasari Anggun Citra Dini Dwi
Published: January 2024

Pacitan adalah salah satu kota yang mempuyai banyak sekali aneka ragam keindahan alam khususnya sektor dibidang pariwisata untuk penunjang ekonomi. Minimnya penyedia layanan informasi terkemuka, keterbatasan wadah promosi, dan banyaknya halaman website yang harus dibuka untuk mendapatkan informasi membuat sebagian besar pengakses atau pengunjung akan mengeluh untuk mencari data yang sesuai. Tujuan Penelitian ini adalah untuk membuat model aplikasi pariwisata berbasis Android dengan mengunakan mobile ui flutter dalam membangunnya supaya menjadi trobosan baru dan efisien membantu para pengguna atau wisatawan menemukan informasi yang diingginkan. Metode penelitian yang digunakan oleh peneliti adalah metode Research and Development (R&D) yaitu suatu metode penelitian yang digunakan untuk membuat sebuah item tertentu, dan menguji kelayakan metode strategi tersebut dengan menggunakan teori, pengetahuan, dan teknik yang dikumpulkan. Peneliti menarik kesimpulan bahwa aplikasi yang telah dibuat dapat mempermudah wisatawan atau pengguna untuk mendapatkan informasi. Proses penyajian informasi data menjadi lebih efektif dan tertata sempurna dalam kumpulan data yang didapat secara terus-menerus di database real time. Kata Kunci : Aplikasi Pariwisata, Mobile Ui Flutter, Android
Penerapan Algoritma C4.5 dalam Memprediksi Calon Siswa Baru
Authors: Gustiarto Erpan
Published: January 2024

Permasalahan yang dihadapi adalah pihak sekolah kesulitan dalam memprediksi calon siswa baru karena masih dilakukan secara manual, kemudian belum ada nya suatu sistem aplikasi dalam memprediksi calon siswa baru membuat kinerja bagian akademik terhambat setiap tahunnya. Tujuan dirancangnya suatu sistem aplikasi prediksi calon siswa baru agar memudahkan pimpinan dalam menerima siswa baru pada setiap tahunnya dari hasil kinerja dan proses perhitungannya terkomputerisasi dengan menggunakan algoritma C4.5. Metode yang digunakan dalam penelitian ini adalah C4.5 dalam penyelesaian permasalahan yang sudah diteliti. Hasil yang didapat dalam penelitian ini yaitu menghasilkan laporan data hasil calon siswa baru pada Sekolah Internasional Tutor Time Indonesia yang akurat sehingga dapat membantu dalam membuat strategi di masa yang akan datang.  Sistem aplikasi yang dirancang sudah layak digunakan untuk proses penilaian prediksi calon siswa baru pada Sekolah Internasional Tutor Time karena sudah sesuai dengan kebutuhan, sehingga dapat mempermudah pimpinan dalam proses penginputan data serta pembuatan laporan.
PEMBANGUNAN TAMAN BACA KUTU BUKU SISWA (KUBUS) UNTUK MEMBANGUN MINAT LITERASI ANAK DI DESA BUNCITAN SEDATI
Authors: Maulidiawati Tasya , Wardhana Setya F. D. W. , Rachmalia Aisyah Dinda , Siahaan Sri Winengsih , Rahmawati Nur Julia , Yunindasari Dwi Resti , Tribhuwaneswari Annisa Budhiyani
Published: January 2024

Budaya literasi perlu ditingkatkan seiring dengan berkembangnya zaman dan kemajuan teknologi. Sasaran utama pelaksanaan kegiatan ini adalah anak usia TK, SD serta semua pelajar di Desa Buncitan Sedati Sidoarjo. Membaca merupakan modal utama untuk kemajuan semua pelajar, oleh karena itu hobi membaca perlu dikembangkan dalam masyarakat sejak dini, mengingat perkembangan teknologi mulai menimbulkan distrupsi terhadap minat baca. Taman Baca merupakan wadah atau tempat yang ideal sebagai wahana bermain, belajar, serta untuk mengembangkan kecintaannya terhadap membaca. Oleh karena itu, pembangunan Taman Baca di Desa Buncitan diharapkan dapat membangun budaya literasi untuk anak - anak. Metode yang digunakan untuk pembangunan taman baca ini yaitu dengan menggunakan metode sosialisasi kepada perangkat desa dan juga kepada masyarakat di desa Buncitan Sedati dengan dibantu oleh karang taruna.
PEMBEKALAN MANAJEMEN PEMASARAN BAGI PEDAGANG DI RT 01 RW 01 PONDOK KOPI JAKARTA TIMUR
Authors: Jamaludin Agus , Widiarto Toto
Published: January 2024

Pedagang adalah salah satu pekerjaan untuk mencari rezeki dengan mengadakan jual beli produk dengan memuaskan konsumen dan bertujuan untuk mendapatkan keuntungan. Pemasaran yaitu suatu proses pengelolaan pemasaran produk kepada konsumen yang mereka butuhkan dengan menukarkan nilai kepada konsumen dengan memberikan kepuasan. Pelanggan adalah orang yang selalu membeli produk yang dibutuhkan di perusahaan karena pelayanan yang diberikan kepada pelanggan, sehinga perusahaan mendapatkan keuntungan. Maka perusahaan berorientasi pada pemasaran yang tujuannya adalah membangun kepuasan pelanggan. Program Pengabdian Masyarakat ini metode yang digunakan adalah pembekalan materi Manajemen Pemasaran kepada pedagang di RT 01 RW 01 Kelurahan Pondok Kopi Jakarta Timur sebanyak 20 orang ,dengan mengunjungi pedagang secara door to door dan mengadakan tanya jawab, sehingga pedagang mengerti tentang produk yang berkualitas, penetapan harga yang bersaing, tempat yang strategis , pelayanan yang memuaskan, dan bagaimana promosi yang efektif.
POSTER SEBAGAI MEDIA PEMBELAJARAN KESEHATAN DAN KESELAMATAN KERJA DI SMK HUTAMA BEKASI
Authors: Saputra Maskhur Dwi , Ningtyas Septiana Ika
Published: January 2024

Media merupakan suatu alat untuk menyampaikan informasi dari satu pihak ke pihak lain. Media memiliki berbagai bentuk salah satunya poster. Bentuk media poster telah banyak digunakan diberbagai bidang, termasuk pendidikan. Penerapan media poster ini dilakukan sebagai bentuk kegiatan Pengabdian kepada Masyarakat (PkM) untuk meningkatkan pemahaman peserta didik terkait Kesehatan dan Keselamatan Kerja (K3). Metode yang digunakan dalam kegiatan PkM ini yaitu demonstrasi kelompok. Hal ini dilakukan dengan cara membagi kelas menjadi beberapa kelompok, masing-masing kelompok menunjuk satu anggota untuk maju ke meja guru. Kemudian di meja guru tim PkM menjelaskan materi K3 kepada perwakilan masing-masing kelompok tersebut. Setelah itu masing-masing kelompok kembali ke kelompok asal untuk menjelaskan materi K3 kepada anggotanya dengan menggunakan media poster. Hasil penerapan media poster pada materi K3 ini dilakukan dengan memberikan tes kepada peserta didik. Rata-rata hasil tes sebelum diberikan perlakuan (pretest) sebesar 29,33 dan rata-rata hasil tes setelah diberikan perlakuan (posttest) sebesar 68.
PEMBUATAN JENAMA GERAKAN “HALO SAYA DISABILITAS”
Authors: Susanti Dewi Indah , Hadiprawiro Yulianto , Hidayati Atiek Nur , Dawami Angga Kusuma , Saptodewo Febrianto
Published: January 2024

Jenama merupakan bagian penting dalam pembentukan konstruksi pemikiran tentang sebuah kampanye. Dosen dan mahasiswa berkolaborasi untuk mendukung kegiatan pembuatan jenama dalam program MBKM. Tujuannya jelas untuk menerapkan ilmu yang telah diajarkan dalam kelas. Kegiatan ini berbentuk kegiatan pembelajaran kreatif dengan studi kasus pembuatan sebuah gerakan “Halo Saya Disabilitas” yang bekerjasama dengan SDS IT Nurul Yaqin dan EPIC School of Autistics. Metode  kegiatan dalam PkM ini menggunakn metode yang dilakukan secara bertahap yaitu diawali dengan merencanakan kegiatan. Pembentukan tim kreatif ada pada tahap ini, berikutnya, tahap  pelaksanaan  guna membentuk jenama dan film animasi,  dan  tahap  terakhir adalah perbaikan melalui FGD serta rencana tindak lanjut. Adapun kegiatan yang dilakukan dalam pengabdian ini yaitu ada tiga kegiatan, yaitu mendefinisikan masalah dengan menggunakan creative brief, membantu proses kreatif dalam mengeksplorasi gerakan ini, dan membantu membuat karya desain yang berbasis pada teknologi. Hasil analisis pelaksanaan pengabdian ini adalah terbentuknya rencana aplikasi desain yang berbasis pada komunikasi, ide, serta penyebarannya.
PENGEMBANGAN MEDIA PEMBELAJARAN BERBASIS ANIMASI POWTOON PADA MATERI SALAT JAMAK DAN QASAR DALAM PAI DI SMPN I PANYABUNGAN BARAT
Authors: Putri Rahmida , Mukti Abd. , Ananda Rusydi
Published: January 2024

Penelitian ini bertujuan untuk mengetahui efektifitas, efektivitas dan kepraktisan pengembangan media pembelajaran animasi powtoon berbasis materi jamak dan qasar di SMP Negeri I Panyabungan Barat. Penelitian ini mengadopsi metode R&D (Research and Development). Model pengembangan yang digunakan adalah model pengembangan Thiagarajan, dan penelitian ini mengadopsi model pengembangan 4-D, yang meliputi empat tahap yaitu definisi, desain, pengembangan, dan diseminasi. Hasil dari studi pengembangan ini adalah 1). Penilaian verifier Media dan Materi yang diperoleh memiliki tingkat validitas skor rata-rata keseluruhan 85,5%, atau menggunakan kriteria sangat baik atau sangat efektif dalam pembelajaran 2). Hasil angket sebelum menggunakan media (pre-test) mendapat 70,4 poin, dan hasil analisis data angket setelah menggunakan media (post-test) mendapat 89,4 poin. Setelah data diperoleh, bandingkan dan terakhir gunakan rumus N-Gain untuk menghitung selisih/perbandingan keduanya. Berdasarkan hasil diffing/comparing keduanya menggunakan rumus N-Gain diperoleh nilai 0,64. 3) Tingkat kepraktisan berdasarkan hasil analisis tanggapan guru PAI terhadap angket, dengan rata-rata 4,68, dengan standar praktik baik/cukup. Hasil analisis respon siswa terhadap angket sebesar 7,38, dan penggunaan media pembelajaran praktikum dalam melaksanakan pembelajaran sebanyak siswa yang merespon hal tersebut.

 
PROBLEMATIKA PEMBELAJARAN BAHASA INDONESIA KELAS III DI SEKOLAH DASAR
Authors: Utaminingsih Esty Setyo , Sulasih Sulasih , Puspita Maria Ayu , Sumartiningsih Sri , Habibi Ahmad Fajar , Mulyaningtiyas Tri
Published: January 2024

This research examines further related problems or problems in learning Indonesian in class III at Gombang Blora State Elementary School. The research method used a qualitative research method with a descriptive approach. The sampling technique used total sampling, where the respondents were a teacher and all third-grade students. The results showed that there were several problems in learning the Indonesian language for third-grade elementary schools, which were divided into four, including (1) learning media which were limited to textbooks from the Ministry of Education, there was no innovation in teaching materials, (2) listening skills were still low, the concentration of students is not good, and the motivation of students is still lacking in participating in the learning process, (3) learning strategies are monotonous and not yet innovative so that students are easily bored and less interested, (4) the ability of teachers in delivering material. Based on the problems, it is necessary to innovate the delivery of learning material by the teacher.
PENGARUH LAYANAN BIMBINGAN KELOMPOK TERHADAP KEMANDIRIAN BELAJAR SISWA SMP DWI WARNA JAKARTA BARAT
Authors: Rahmah Zulfah Aulia , Nuraini Nuraini
Published: January 2024

Masalah dalam penelitian ini adalah bahwa siswa tertentu di SMP Dwi Warna Jakarta Barat tidak terlibat dalam pembelajaran mandiri. Dengan memberikan layanan bimbingan dan konseling, termasuk layanan bimbingan kelompok, hal ini dapat dihindari. Untuk siswa SMP Dwi Warna Jakarta Barat tahun ajaran 2022–2023, penelitian ini bertujuan untuk mengetahui pengaruh layanan bimbingan kelompok terhadap kapasitas kemandirian belajar siswa kelas VIII SMP Dwi Warna Jakarta Barat. Dalam penelitian ini, menggunakan metode eksperimen dengan desain pre-experimental menggunakan pendekatan one-group pretest-posttest design. Purposive sampling digunakan untuk mengumpulkan data dari 15 siswa peserta penelitian, dengan jumlah sampel 10. Hasil penelitian menunjukkan bahwa kategori tinggi (100%) terdiri dari 10 siswa dari sebelumnya 10% dengan 1 siswa, sedang kategori (0%) terdiri dari 0 siswa dari sebelumnya 60% sebanyak 6 siswa, dan kategori rendah (0%) yaitu terdiri dari 0 siswa dari sebelumnya 30% dengan jumlah 3 siswa. Dengan demikian, dapat dikatakan bahwa layanan bimbingan kelompok di SMP Dwi Warna Jakarta Barat dapat membantu siswa kelas VIII untuk menjadi pembelajar yang lebih mandiri.
EFEKTIVITAS LAYANAN BIMBINGAN KELOMPOK DENGAN TEKNIK ROLE PLAYING UNTUK MENGURANGI PERILAKU AGRESIF SISWA SMPN 103 JAKARTA
Authors: A’yun Afifah Azzahra Qurrota , Asni Asni
Published: January 2024

Siswa adalah bagian penting dari lembaga pendidikan. Setiap siswa diharap  untuk bertindak positif, memiliki kepribadian yang baik, memiliki karakter yang kuat yang tidak dipengaruhi oleh orang lain, dan memiliki gagasan yang baik, jika tidak tegas. Tujuan penelitian ini adalah untuk mengetahui keefektifan layanan bimbingan kelompok dengan teknik bermain peran dalam menurunkan agresi pada siswa kelas VIII-9 SMP Negeri 103 Jakarta tahun ajaran 2023. Pendekatan yang digunakan adalah pendekatan kuantitatif yang sesuai dengan sifat penelitian. Jenis penelitian ini adalah penelitian pre-experimental dengan desain single group pretest and posttest design. Dari hasil tersebut, dari 36 item yang ada, 31 item tersedia untuk penelitian. Populasi penelitian berjumlah 32 orang siswa dengan menggunakan teknik pengambilan sampel yang disebut purposeful sampling. Sampel terdiri dari 10 siswanya. Instrumen yang digunakan adalah angket untuk menguji reliabilitas rumus yang digunakan dalam rumus Alpha-Cronbac, sedangkan pengujian hipotesis digunakan pada teknik analisis data penelitian ini. Pengujian hipotesis dengan menggunakan signed Wilcoxon ranks dapat disimpulkan bahwa layanan bimbingan kelompok dengan teknik bermain peran dapat mengurangi perilaku agresif siswa kelas VIII SMP Negeri 103 Jakarta.
THE INFLUENCE OF STUDENT MANAGEMENT AND THE PROGRAM INDONESIA PINTAR (PIP) ON STUDENT ACHIEVEMENT AT SMAN 1 RUNDENG KOTA SUBULUSSALAM
Authors: Yuliana Yuliana , Azmi Fachruddin , Rifa'i Muhammad
Published: January 2024

Student management plays a vital role in attaining student achievement as it oversees all aspects of student activities from school entry to graduation. Additionally, the government provides financial support through the Program Indonesia Pintar (PIP) to aid students who may face challenges in their studies. This study aims to determine 1) The significant effect of student management on student achievement at SMA Negeri 1 Rundeng. 2) The significant influence of scholarship recipients from the Program Indonesia Pintar on student achievement in Negeri 1 Rundeng. 3) The significant effect of student management and the Program Indonesia Pintar (PIP) on student achievement at SMA Negeri 1 Rundeng. This research method uses quantitative research methods using the ex post facto approach. The population in the study were students of SMA Negeri 1 Rundeng, totaling 155 people and the research sample was 54 people. the instrument in this study used a questionnaire sheet. The data analysis technique in this study used multiple regression analysis. The results showed that 1) there was a significant influence of student management on student achievement at SMA Negeri 1 Rundeng with a significance value of 0.023 < 0.05. 2) there is a significant influence from the Program Indonesia Pintar (PIP) on student achievement at SMA Negeri 1 Rundeng with a significance value of 0.049 < 0.05. 3) there is a significant influence of student management and the Program Indonesia Pintar (PIP) on student achievement at SMA Negeri 1 Rundeng with a significance value of 0.005 < 0.05.
PENGGUNAAN BOARD GAME SEBAGAI MEDIA PEMBELAJARAN UNTUK MELATIH BERPIKIR KREATIF SISWA
Authors: Ningtyas Septiana Ika
Published: January 2024

Kurikulum merdeka yang dicanangkan saat ini pembelajaran yang biasanya terfokus pada guru dan tarpaut pada kemampuan kognitifnya menjadi pembelajaran yang fokus pada keaktifan siswa dan guru sebagai fasilitator sedangkan kemudahan teknologi saat ini membuat anak kecanduan pada permainan yang ada pada smartphone yang membuat proses berpikir menjadi terhambat. Oleh karena itu, penelitian ini bertujuan untuk melatih siswa untuk berpikir kreatif melalui media yang menyenangkan, yaitu board game. Penelitian ini menggunakan metode deskriptif kualitatif dimana menggunakan key informan sebagai pengambilan data primer serta observasi dan catatan lapangan sebagai data sekunder. Hasil dari penelitian ini adalah siswa PAUD yang diberikan boardgame sebagai media pembelajaran jauh lebih interaktif dan banyak bercerita, penggunaan boardgame dilakukan berkala sehingga siswa dapat menikmati proses belajar dengan lebih mudah kemudian media pembelajaran boardgame seperti monopoli yang digunakan di PAUDQU Al-Banna lebih efektif digunakan ketimbang dengan pembelajaran menggunakan penjelasan di meja saja. Proses berpikir kreatif siswa saat penggunaan boardgame lebih jelas terlihat, dengan aturan sederhana yang dibuat siswa tetap patuh terhadap aturan tersebut dan juga berjiwa besar dan berani jika tiba gilirannya melakukan tantangan serta siswa diberikan hak untuk mengungkapkan, berekspresi dan juga menunjukkan keinginannya yang terkadang lain dari biasanya namun disitulah proses berpikir kreatif terbentuk.
 
PENGELOLAAN DANA BANTUAN OPERASIONAL SEKOLAH (BOS) DALAM MENINGKATKAN SARANA DAN PRASARANA DI MADRASAH TSANAWIYAH SWASTA AL IHSAN MEDAN
Authors: Rahman Muhammad Yandi , Siahaan Amiruddin , Hadijaya Yusuf
Published: January 2024

Penelitian ini bertujuan untuk mengetahui pengendalian Dana Bantuan Operasional Sekolah (BOS) dalam meningkatkan sarana dan prasarana pendidikan di MTs Al-Ihsan Medan, kewajiban kepala madrasah dalam Dana Bantuan Operasional Sekolah untuk mengembangan sarana dan prasarana pendidikan di MTs Al-Ihsan Medan, faktor yang mempengaruhi penghambat dan Pendukung dalam pengelolaan dana Bantuan Operasional Sekolah (BOS) dalam menunjang sarana dan prasana pendidikan di MTs Al-Ihsan Medan Penelitian ini menggunakan jenis penelitian eksploratif kualitatif. Penelitian ini dilakukan di Madrasah Tsanawiyah swasta Al- Ihsan Jalan Jemadi No. 18.A. Pulo Brayan Darat-II. Kecamatan Medan Timur 20239. Adapun hasil penelitian hasil penelitian mengenai Pengelolaan Dana Bantuan Operasional Sekolah Dalam Meningkatkan Sarana dan Prasarana di MTs Swasta Al-Ihsan Medan yaitu; 1) Pelaksanaan administrasi dana BOS di MTs Al-Ihsan Medan selama masa peredaran dan dana BOS tidak mengalami kendala serta sesuai pedoman khusus BOS untuk Madrasah; 2) Komitmen kepala sekolah pada dana bantuan oprasional Sekolah untuk membina lembaga dan kerangka kerja di MTs Al-Ihsan Medan Kepala Madrasah MTs Al-Ihsan Medan memiliki beberapa hal, yaitu persiapan, koordinasi, perolehan; 3) Pengelolaan dana BOS di MTs Al-Ihsan Medan tidak menemui kendala yang krusial.
IS TRANSLATION IN HIGHER EDUCATION AN ACADEMIC OR VOCATIONAL FIELD?
Authors: Anggini Wulan Yulian , Helmanto Fachri
Published: January 2024

Undergraduate higher education in many countries are common to teach translation theories in a class while the students need more practice as close as the professional translator does. The purpose of this study is to explore how undergraduate higher education institution administering the translation class in Indonesia. This study used an exploratory case study method on a translation class of an English Education study program year 2022 with data gathered are from the learning documents, lecturers, and students. The data are analyzed using thematic analysis following steps familiarization, coding, generating, reviewing, defining, naming theme and writing up. The themes are validated using data triangulation that cross checking among the collected data. This study shows that the undergraduate level prepares the academic field of translation that will serve as a base of knowledge to pursue advanced level in the academic and/or goes to specialize for becoming professional translator later. It is recommended to have further study on how to teach the academic field of translation, such as translation teaching model, teaching method, assessment and so on.
The Use of Reparametrization and Constraints on Linear Models to Parse Qualitative and Quantitative Information for a Set of Predictors
Authors: Davenport Ernest C. , Davison Mark L. , Park Kyungin
Published: January 2024

The following study shows how reparameterizations and constraints of the general linear model can serve to parse quantitative and qualitative aspects of predictors. We demonstrate three different approaches. The study uses data from the High School Longitudinal Study of 2009 on mathematics course-taking and achievement as an example. Results show that all mathematics courses are not equally predictive of math achievement. Thus, taking into account qualitative aspects of mathematics courses is useful. The study ends with a justification of quantifying qualitative aspects of predictors relative to a criterion with extensions to other linear models.
Vulvar Melanoma: Clinical Features, Diagnosis, Staging, Treatment and Prognosis
Authors: Zhao Jinduo , Cao Nanyu
Published: January 2024

Objective: This article presents a review of the current diagnosis and treatment of vulvar melanoma in detail to provide useful references for the diagnosis and treatment of the disease in the future. Mechanism: In this review, the author first specifies the topic of the article and the content covered. PubMed was searched for a series of keyword combinations related to the topic, and there was extensive reading of search engine- and database-derived literature from 1970–2022 related to the vulvar melanoma guidelines, including randomized clinical studies, observational studies, and basic research. Based on the published content, the articles were screened according to the year of publication, the number of citations, and the publishing unit. The data and content needed in each article were collected. Finally, the collected data were summarized to provide an in-depth introduction to vulvar melanoma, a rare disease, covering the aspects of clinical features, diagnosis, staging, treatment and prognosis. Findings in Brief: Through this review, we gain a comprehensive understanding of the current diagnosis and treatment of vulvar melanoma and the breakthrough direction of future research. Conclusions: At present, the main diagnostic methods in cases of vulvar melanoma include macroscopic examination, dermoscopy, microscopy, histopathology and imaging examination. The main treatment modalities for vulvar melanoma are surgery, radiotherapy, chemotherapy, immune checkpoint inhibitors, targeted therapy and immune modulators.
Perinatal Outcomes were Associated with the Positional Relationship between Placenta and Adenomyotic Lesion in Pregnant Patients with Adenomyosis
Authors: Xu Ping , He Xiaoqing , Zhang Yanan , Wang Yayun , Zou Gen , Wang Jianzhang , Zhang Xinmei
Published: January 2024

Background: The adverse perinatal outcome caused by adenomyosis has been widely concerned recently, but little attention has been paid to whether the positional relationship between placenta and adenomyotic lesion influences the maternal and perinatal outcomes. Methods: A total of 311 women with adenomyosis who were pregnant greater than 20 weeks gestation and delivered at Women’s Hospital, Zhejiang University School of Medicine between January 2010 and December 2021 were recruited. The positional relationships between placenta and adenomyotic lesions were determined. The patients were divided into two subgroups: group 1, placenta located on or above the adenomyotic lesion; and group 2, placenta located far away from the adenomyotic lesion. The clinical data of two groups were retrospectively analyzed. Results: We found a higher rate of diffuse adenomyosis (62.65% vs. 46.21%, p = 0.01), coexisting endometriosis (31.93% vs. 15.86%, p = 0.002), preterm delivery (34.94% vs.15.17%, p < 0.001) and placenta malposition (19.88% vs. 6.90%, p = 0.002) in group I compared to group II. Compared with group II, group I had lower birth weight (p = 0.02). After adjustment using multiple logistic regression analysis, maternal adverse outcome was only correlated with age (p = 0.02). Neonatal adverse outcomes were closely correlated with group I (p = 0.004), including pregnancy induced hypertension (p = 0.01), placenta malposition (p = 0.02), placental abruption (p = 0.003), and scarred uterus (p = 0.02). Conclusions: The positional relationships between the placenta and adenomyotic lesions were graphically presented. Placental position near or above adenomyosis lesions might correlate to the adverse perinatal outcomes of pregnant women with adenomyosis and thereby deserve more attention.
Immunohistochemical Analysis of Vimentin and Zonula Occludens-1 in Placentas of Patients with PPROM
Authors: Zaman Fuat , Aşır Fırat , Ermiş Işılay Sezen , Tuncer Mehmet Cudi , Deveci Engin , Oğlak Süleyman Cemil
Published: January 2024

Background: We aimed to investigate the immunohistochemical staining of vimentin and zonula occludens-1 (ZO-1) expression in the placentas of pregnant women with preterm premature rupture of membranes (PPROM). Methods: Placentas of 25 healthy and 25 women with PPROM were fixed in 10% formaldehyde solution and further processed for paraffin wax tissue embedding. Demographic properties of patients were recorded. Placentas were histologically stained with hematoxylin-eosin and vimentin and ZO-1 expression immunostaining. Results: Vimentin expression was high in the decidual cells, fibroblasts, and connective tissue fibers in control group. Compared to control group, vimentin expression was decreased in the placental structures of PPROM group, where fetal membranes were degenerated and histologically irregular. Similar to vimentin expression, ZO-1 expression was also high in placental components of control group such as chorioamniotic membrane and amniotic epithelium. The PPROM group showed lower expression of ZO-1 expression in placental structures than in that of control. ZO-1 expression was significantly lowered in regions where fetal membrane integrity was weakened and lost. Conclusions: We suggest that ZO-1 and vimentin expression may show alteration in etiology premature rupture of membrane.
Analysis of Clinical Effect and Influencing Factors for Conservative Treatment in Ectopic Pregnancy
Authors: Xia Huan , Tang Huimin , Jia Qiucheng , Chen Yao , Shan Wulin , Liu Wenying , Su Cuiying , Chen Jiming
Published: January 2024

Background: The curative effect of four different kinds of conservative treatment of ectopic pregnancy (EP) and the risk factors affecting the curative effect of conservative treatment of ectopic pregnancy were compared and analyzed. Methods: Retrospective analysis of the clinical data of patients with ectopic pregnancy treated conservatively in our hospital during the last 10 years. We compared and analyzed the clinical efficacy of four regimens: the expectant treatment, methotrexate (MTX), and methotrexate combined with mifepristone. Logistic regression was used to analyze the influencing factors of the curative effect for conservative treatment of ectopic pregnancy. Results: Initial serum of β human chorionic gonadotrophin (β-hCG) for the four groups of patients demonstrated statistically significant differences in β-hCG level and treatment success rate between groups (p < 0.05). When the serum β-hCG level was less than 1000 mIU/mL, the levels in the expected treatment group and mifepristone group were statistically significant (p = 0.002). There were no statistically significant differences in the treatment success rates between the four groups (p = 0.263). When the serum β-hCG level was ≥1000 mIU/mL, the treatment success rate of MTX combined with mifepristone group (9/15, 60%) was significantly higher than that of the other treatment groups (10/34, 29.4%). This difference was statistically significant (p = 0.045). When logistic regression analysis was performed, the initial serum β-hCG level (odds ratio (OR) = 0.999, 95% confidence interval (95% CI) 0.999–1) and abdominal pain score (OR = 0.4, 95% CI 0.267–0.6) were independent risk factors affecting the success of conservative treatment of ectopic pregnancy. Conclusions: Initial serum β-hCG level and abdominal pain score are the main risk factors affecting the success of conservative treatment of EP. When the serum β-hCG level was less than 1000 mIU/mL, there was no significant difference between the four conservative treatment regimens. When the serum β-hCG level was ≥1000 mIU/mL, the cure rate of MTX combined with mifepristone had obvious advantages over other regimens.
Delivery Mode and the Pelvic Floor Function of Primiparous Women at Early Postpartum: An Observational Retrospective Cohort Study
Authors: Chi Xiaolei , Wen Lin , Chen Lan , Zhu Hongxia
Published: January 2024

Background: Different modes of delivery are strongly associated with postpartum pelvic floor muscle (PFM) injury and postpartum pelvic floor dysfunction. This study used Glazer PFM surface electromyography (sEMG) to objectively assess postpartum PFM function to determine the effects of different modes of delivery on pelvic floor function in the early postpartum period in primiparous women. Methods: There were 1286 cases of cesarean delivery (CD) and 2099 cases of vaginal delivery (VD). The vaginal delivery group was further divided into four subgroups (A: intact perineum without laceration and first-degree laceration; B: second-degree laceration; C: mediolateral episiotomy; D: forceps delivery). Pelvic floor sEMG indices of the subjects were analyzed at 6–8 weeks postpartum. Results: The results showed that the mean peak amplitude of phasic (flick) contractions and the mean amplitude of tonic contractions were both significantly higher in CD than in VD (p < 0.01). In contrast, the mean amplitude variability of tonic contractions was lower in CD than in VD (p < 0.01). The mean peak amplitude of phasic (flick) contractions and the mean amplitude of tonic contractions were statistically lower in the forceps group than in the other vaginal delivery groups (p < 0.05). The mean amplitude variability of tonic contractions was greater in the forceps group than in groups A, B and C (p < 0.01). Conclusions: Vaginal delivery, especially forceps delivery, may result in impaired pelvic floor muscle function in the early postpartum period compared to cesarean delivery.
Huaier Regulates Oxaliplatin Resistance in Colorectal Cancer by Regulating Autophagy and Inhibiting the Wnt/β-catenin Signalling Pathway
Authors: Feng Qi , Huo Mingyi , Yan Xiaoli , Wen Luwen , Zheng Jining
Published: January 2024

Objective: The present study aims to investigate the effect of Huaier on oxaliplatin (OXA) resistance in HCT-8 colorectal cancer (CRC) cells. Methods: Oxaliplatin-resistant HCT-8/L CRC cells were used. The Cell Counting Kit-8, western blotting, quantitative real-time polymerase chain reaction, protein extraction kit, immunofluorescence and acridine orange staining assays were used in the study. The experiment results proved that Huaier has an influence on the Wnt/β-catenin signalling pathway, autophagy and drug resistance. The authors of the present study used chloroquine, an autophagy inhibitor and Wnt agonist 1 (a Wnt pathway agonist) to verify the present experiment. Results: The results showed that Huaier can regulate autophagy, inhibit the Wnt/β-catenin signalling pathway and reverse the drug resistance of OXA-resistant CRC cells. Conclusions: This study proved that Huaier can regulate autophagy, inhibit the Wnt/β-catenin signalling pathway and reverse the drug resistance of OXA-resistant CRC cells.
Machine and Deep Learning: Artificial Intelligence Application in Biotic and Abiotic Stress Management in Plants
Authors: Gou Caiming , Zafar Sara , Fatima  , Hasnain Zuhair , Aslam Nazia , Iqbal Naeem , Abbas Sammar , Li Hui , Li Jia , Chen Bo , Ragauskas Arthur J. , Abbas Manzar
Published: January 2024

Biotic and abiotic stresses significantly affect plant fitness, resulting in a serious loss in food production. Biotic and abiotic stresses predominantly affect metabolite biosynthesis, gene and protein expression, and genome variations. However, light doses of stress result in the production of positive attributes in crops, like tolerance to stress and biosynthesis of metabolites, called hormesis. Advancement in artificial intelligence (AI) has enabled the development of high-throughput gadgets such as high-resolution imagery sensors and robotic aerial vehicles, i.e., satellites and unmanned aerial vehicles (UAV), to overcome biotic and abiotic stresses. These High throughput (HTP) gadgets produce accurate but big amounts of data. Significant datasets such as transportable array for remotely sensed agriculture and phenotyping reference platform (TERRA-REF) have been developed to forecast abiotic stresses and early detection of biotic stresses. For accurately measuring the model plant stress, tools like Deep Learning (DL) and Machine Learning (ML) have enabled early detection of desirable traits in a large population of breeding material and mitigate plant stresses. In this review, advanced applications of ML and DL in plant biotic and abiotic stress management have been summarized.
KLF8 Promotes the Survival of Lung Adenocarcinoma During Nutrient Deprivation by Regulating the Pentose Phosphate Pathway through SIRT2
Authors: Bai Qiaohong , Jin Wenfang , Chen Futao , Zhu Jiang , Cao Lifeng , Yang Yang , Zhong Fukuan , Li Li
Published: January 2024

Background: The pentose phosphate pathway (PPP) is a critical metabolic pathway that generates NADPH and ribose-5-phosphate for nucleotide biosynthesis and redox homeostasis. In this study, we investigated a potential regulatory role for Krüppel-like factor 8 (KLF8) in the control of PPP in lung adenocarcinoma (LUAD) cells. Methods: Based on a comprehensive set of experimental approaches, including cell culture, molecular techniques, and functional assays, we revealed a novel mechanism by which KLF8 promotes the activation of glucose-6-phosphate dehydrogenase (G6PD), a component enzyme in the PPP. Results: Our findings demonstrate that KLF8 inhibits the acetylation of G6PD, leading to its increased enzymatic activity. Additionally, we observed that KLF8 activates the transcription of SIRT2, which has been implicated in regulating G6PD acetylation. These results highlight the interplay between KLF8, G6PD, and protein acetylation in the regulation of PPP in LUAD. Conclusions: Understanding the intricate molecular mechanisms underlying the metabolic reprogramming driven by KLF8 in lung cancer provides valuable insights into potential therapeutic strategies targeting the PPP. This study emphasizes the significance of KLF8 as a key modulator of metabolic pathways and indicates the potential of targeting the KLF8-G6PD axis for lung cancer treatment.
Downregulation of MTHFD2 Inhibits Proliferation and Enhances Chemosensitivity in Hepatocellular Carcinoma via PI3K/AKT Pathway
Authors: Wang Jie , Yu Ze , Jiang Yixiao , Le Ting , Wu Yixin , Li Ziqi , Zhang Guoqiang , Wu Feiyue , Ma Haijie
Published: January 2024

Background: Despite the substantial impact of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) on cancer progression, its significance in the regulation of hepatocellular carcinoma (HCC) cell proliferation and chemosensitivity remains poorly defined. Methods: We evaluated MTHFD2 expression in a total of 95 HCC tissues by immunohistochemistry and analyzed the association of MTHFD2 with clinicopathologic features. qRT-PCR and Western blotting were conducted to verify MTHFD2 expression levels. Bioinformatics analysis such as gene set enrichment analysis (GSEA) and kyoto encyclopedia of genes and genomes (KEGG) enrichment analysis were used to predict the signaling pathways involved in MTHFD2. In addition, to investigate the anti-tumor effects of MTHFD2 knockdown, Cell Counting Kit-8 (CCK-8) and EdU assays were used. Results: We found that MTHFD2 was frequently upregulated in HCC, and the combination of increased expression of MTHFD2 and Ki67 was associated with poor HCC prognosis. MTHFD2 knockdown significantly inhibited HCC cell proliferation and effectively sensitized HCC cells to sorafenib and lenvatinib. PI3K/AKT pathway was involved in MTHFD2-mediated modulation of proliferation and chemosensitivity. Conclusions: These findings indicate that MTHFD2 plays an important role in proliferation and chemosensitivity of HCC, indicating that it may serve as a novel pharmacological target for improving HCC therapy.
Aberrant White Matter Development in Cerebral Visual Impairment: A Proposed Mechanism for Visual Dysfunction Following Early Brain Injury
Authors: Bauer Corinna M. , Merabet Lotfi B.
Published: January 2024

Background: Cerebral visual impairment (CVI) is a common sequala of early brain injury, damage, or malformation and is one of the leading individual causes of visual dysfunction in pediatric populations worldwide. Although patients with CVI are heterogeneous both in terms of underlying etiology and visual behavioural manifestations, there may be underlying similarities in terms of which white matter pathways are potentially altered. This exploratory study used diffusion tractography to examine potential differences in volume, quantitative anisotropy (QA), as well as mean, axial, and radial diffusivities (mean diffusivity (MD), axial diffusivity (AD) and radial diffusivity (RD), respectively) focusing on the dorsal and ventral visual stream pathways in a cohort of young adults with CVI compared to typically sighted and developing controls. Methods: High angular resolution diffusion imaging (HARDI) data were acquired in a sample of 10 individuals with a diagnosis of CVI (mean age = 17.3 years, 2.97 standard deviation (SD), range 14–22 years) and 17 controls (mean age = 19.82 years, 3.34 SD, range 15–25 years). The inferior longitudinal fasciculus (ILF), inferior fronto-occipital fasciculus (IFOF), vertical occipital fasciculus (VOF), and the three divisions of the superior longitudinal fasciculus (SLF I, II, and III) were virtually reconstructed and average tract volume (adjusted for intracranial volume), MD, AD, and RD were compared between CVI and control groups. As a secondary analysis, an analysis of variance (ANOVA) was carried out to investigate potential differences based on etiology (i.e., CVI due to periventricular leukomalacia (CVI-PVL) and CVI due to other causes (CVI-nonPVL)). Results: We observed a large degree of variation within the CVI group, which minimized the overall group differences in tractography outcomes when examining the CVI sample as a unitary group. In our secondary analysis, we observed significant reductions in tract volume in the CVI-PVL group compared to both controls and individuals with CVI due to other causes. We also observed widespread significant increases in QA, MD, and AD in CVI-PVL compared to the control group, with mixed effects in the CVI-nonPVL group. Conclusions: These data provide preliminary evidence for aberrant development of key white matter fasciculi implicated in visual perceptual processing skills, which are often impaired to varying degrees in individuals with CVI. The results also indicate that the severity and extent of the white matter changes may be due in part to the underlying cause of the cerebral visual impairments. Additional analyses will need to be done in a larger sample alongside behavioural testing to fully appreciate the relationships between white matter integrity, visual dysfunction, and associated causes in individuals with CVI.
Differences in Functional Activity and Connectivity in the Right Frontoparietal Network between Nurses Working Long-Term Shifts and Fixed Day Shifts
Authors: Dong Yuqin , Wu Xiaohong , Zhou Yang , Qiu Ke
Published: January 2024

Objectives: To investigate the differences in functional brain activity and connectivity between nurses working long-term shifts and fixed day shift and explore their correlations with work-related psychological conditions. Methods: Thirty-five nurses working long-term shifts and 35 nurses working fixed day shifts were recruited. After assessing work-related psychological conditions, such as burnout and perceived stress of these two groups of nurses, amplitude of low-frequency fluctuations (ALFF) and functional connectivity (FC) analyses were performed to investigate the between-group differences in brain functional activity and connectivity. Furthermore, correlation analysis between the ALFF/FC metrics and psychological conditions was conducted. Results: Compared with nurses working fixed day shifts, nurses working long-term shifts showed higher levels of burnout, perceived stress, and depression scores; lower z-transformed ALFF (zALFF) values in the right dorsolateral prefrontal cortex (dlPFC), right superior parietal lobule (SPL), and right anterior cingulate cortex (ACC); and higher zALFF values in the right middle temporal gyrus (voxel-level p < 0.001, cluster-level p < 0.05, gaussian random field (GRF) correction), as well as lower FC values in the right dlPFC-right SPL and right dlPFC-right ACC (p < 0.05, false discovery rate (FDR) corrected). Moreover, the FC values in the right dlPFC-right SPL were negatively correlated with the perceived stress score in nurses working long-term shifts (p < 0.05, FDR corrected). Conclusions: This study demonstrated that nurses working long-term shifts had lower functional activity and weaker functional connectivity in the right frontoparietal network, which mainly includes the right dlPFC and right SPL, than those working on regular day shift. The current findings provide new insights into the impacts of long-term shift work on nurses’ mental health from a functional neuroimaging perspective.
The Neuroprotective Effects of Electroacupuncture on Parkinson's Disease and the Underlying Molecular Mechanisms
Authors: Han Qiuqin , Chen Peiqing , Chen Xiaorong , Wang Lijuan , Huang Renyan , Li Wenhui , Liu Guobin
Published: January 2024

Parkinson’s disease (PD) is a chronic neurodegenerative disease whose main pathological features are the degeneration of dopamine neurons and deposition of α-synuclein in neurons. At present, the most important treatment strategy for PD is drugs, and one of the most used drugs is levodopa. However, this therapy shows many problems, such as tolerance and long-term effects, so other treatment strategies need to be explored. As a traditional Chinese medicine treatment method with effective and few side effects, electroacupuncture is considered a non-drug therapy. It serves as a novel, promising therapeutic approach for the treatment of PD. In this review, the application and the effects of electroacupuncture on PD have been described. Besides, the underlying molecular mechanisms of electroacupuncture on PD that contribute to protecting dopaminergic neurons and reducing α-synuclein levels have been illustrated, including ① anti-oxidant stress response, ② anti-neuroinflammatory response, ③ up-regulation of neurotrophic factors and reduction of nerve cell apoptosis, ④ down-regulation of endoplasmic reticulum stress and improvement of mitochondrial function, ⑤ improvement of the function of the ubiquitin-proteasome system, ⑥ anti-excitatory toxicity response, ⑦ activation of autophagy, and ⑧ modulation of gut microbiota. Achieving a better understanding of the neuroprotective effects of electroacupuncture on PD will provide a theoretical basis and facilitate the application of electroacupuncture on PD.