bluuebunny/crossref_metadata_2025 huggingface dataset:
Racismo e neoliberalismo como elementos subjetivos estruturantes: da dominação colonial em frantz fanon à psicopolítica de Byung-Chul Han
Authors: Sodré de Oliveira Fernando Antônio , Lucas Doglas Cesar , Copetti Santos André Leonardo
Published: September 2022

O presente artigo tem por escopo analisar, ainda que de forma introdutória, a mentalidade neoliberal a partir da experiência histórica do colonialismo pela perspectiva de dominação psíquica em Frantz Fanon e verificar como esta noção comunica-se com as definições atuais da psicopolítica de Byung-Chul Han, se integram e se complementam, partindo da percepção central de que as estruturas neoliberais estão em constante modificação, visando a criar subjetividades moldadas e “dóceis” ao projeto neoliberal, analisando como este processo de “docilização” está vinculado ao racismo – seja como experiência, seja como elemento gerador de submissão psíquica – o qual é elemento estruturante do projeto neoliberal nos países colonizados por meio de processos de dominação e submissão psíquica nos modelos coloniais, neocoloniais e imperiais, fortalecendo e sendo útil ao neoliberalismo e evoluindo para uma instância de autossubmissão na perspectiva psicopolítica de Byung-Chul Han. O presente trabalho dedica-se a desenvolver reflexões sobre como o fenômeno do racismo e sua ligação com a mentalidade neoliberal ajustam-se e, de certa forma, contribuem à efetivação das análises psicopolíticas de Byung-Chul Han. Abordar-se-á a governamentalidade neoliberal como uma racionalidade governamental de exclusão, a qual tem na escravidão o elemento fundante dos sistemas econômicos capitalistas dos países colonizados, bem como o fenômeno da dominação psíquica colonial, estudada por Frantz Fanon, e como a psicopolítica de Byung-Chul Han eleva a um grau mais intenso estes processos de submissão nas populações nos países colonizados, tendo no racismo a tecnologia de efetivação desta mentalidade de submissão e inferiorização, visando a atender ao projeto neoliberal e como os processos psicopolíticos fortalecem a mentalidade neoliberal do “empreendedorismo de si”, alicerçada nessa “sujeição psicopolítica”, articulada nos países colonizados pelo racismo e pelos processos de dominação e submissão psíquica estudados por Frantz Fanon. Utilizar-se-á o método hipotético-dedutivo e a análise bibliográfica para realização desta pesquisa.
Three-Component Betti Condensation for Synthesis of Aminomethylnaphthols Incorporating Deoxy-isoequilenine Scaffold-Absolute Configuration and Application
Authors: Zagranyarska Irena , Kostova Kalina , Dikova Krasimira , Shivachev Boris , Dimitrov Vladimir
Published: September 2022

Chiral aminomethylnaphthols have been prepared highly diastereoselective by means of three-component “Betti condensation”, using steroidal 2-naphthol analogue, synthesized from estrone. The use of 2-methoxybenzaldehyde or 2-pyridinecarboxaldehyde as aldehyde component and (S)-(–)-1-phenylethan-1-amine or (S)-(–)-1-(naphthalen-2-yl)ethan-1-amine, as chiral non-racemic amine component providing the diastereoselectivity, allowed the synthesis of structurally diverse aminomethylnaphthols. The latter easily form 1,3-dihydronaphthoxazines through reaction with formaldehyde. The absolute configurations of the new aminomethylnaphthols synthesized have been determined through advanced nuclear magnetic resonance (NMR) experiments and confirmed by X-ray crystallography. The chiral steroidal aminomethylnaphthols obtained as pure diastereoisomers have been evaluated as pre-catalysts in the enantioselective addition of diethylzinc to aldehydes with enantioselectivities of up to 97% ee.
constitucionalización de los derechos fundamentales laborales en Chile
Authors: Franchi Muñoz Andrés
Published: September 2022

En la actualidad se concibe a los trabajadores como   titulares    de   derechos  fundamentales   inespecíficos,  oponibles a su empleador  al   interior   de   la   relación   de   trabajo,   pasando   en   definitiva   a   constituir   un   límite   a los poderes del empleador, dejando de tener una concepción meramente vertical frente al Estado. Ello obedece a un proceso de relectura de la Constitución 1980, lo que unido al trabajo doctrinal y jurisprudencial en la materia ha permitido estar en frente de lo que hemos denominado “La Constitucionalización de los derechos fundamentales laborales” en nuestro país. Este reconocimiento resulta insuficiente, sino se le otorgaban a dichos derechos mecanismos de tutela judicial efectiva, lo que se hizo mediante la creación y la incorporación del Procedimiento de Tutela Laboral por Vulneración de Derechos Fundamentales.
Two-year Follow-up of Avulsed Teeth Submittted to Laser Therapies: A Case Report
Authors: Belmonte Flavia Monari , Azevedo Luciane Hiramatsu , Paschoal Emilio Carlos , Caldeira Celso Luiz , de Freitas Patricia Moreira
Published: September 2022

Background:

Replanted teeth can lead to critical biological conditions involving ankylosis and external root resorption. To prevent these occurrences, antimicrobial Photodynamic Therapy (aPDT) and Photobiomodulation Therapy (PBMT) can be used during the postoperative phase.

Case Report:

The present report described the clinical case of a patient, an adult male with the avulsion of teeth #11 and #21. Teeth were stored under dry conditions and replanted 18h after trauma. The pulp was removed before replantation and aPDT was performed using a low power laser (660 nm,100 mW, 9 J) in direct irradiation of the root canal. A passive flexible splint was fixed in place from tooth #13 to #23 for 4 weeks. The PBMT was applied three times a week, for the first 2 months, using the same laser device but with an infrared wavelength (808 nm, 100 mW, 3J). Clinical and radiographic examination supported the assessment of inflammatory/infectious resorption.

Conclusion:

The combination of laser therapy with endodontic procedures for treating traumatized teeth ensured successful clinical and radiographic outcomes at a 2-year follow-up examination.
Utilization of Water: Environmental Impact and Health Issues
Authors: Deshpande Bhavna D. , Agrawal Pratibha S. , Yenkie M.K.N. , Dhoble S.J.
Published: September 2022

The availability of pure drinking water to individuals reflects the progress of
any region, which is linked directly with the quality of life across the globe. Variations
in the quality and quantity of water systems control all aspects of human life. Both its
shortage and excess affect the growth and development of the community. The
utilization and conservation of our water world must be an integral part of sustainable
development and should be appealed to by all sectors. While effective wastewater
treatment has the tendency to recover the water, integration of all policies with periodic
improvement using research outcomes is still essential. In order to tackle the challenges
in the coming decades, it is important that all stakeholders are sensitized about the
current scenario, future needs, and the need for a proper scientific and rational
approach to moderate the issues and challenges collectively. Integrated Water
Conservation Techniques are acknowledged as the only sustainable solution to water
scarcity.
Comparing Transactional eHealth Literacy of Individuals With Cancer and Surrogate Information Seekers: Mixed Methods Study
Authors: Vasquez Taylor S , Bylund Carma L , Alpert Jordan , Close Julia , Le Tien , Markham Merry Jennifer , Taylor Greenberry B , Paige Samantha R
Published: September 2022

Background

The number of adults entering higher-risk age groups for receiving a cancer diagnosis is rising, with predicted numbers of cancer cases expected to increase by nearly 50% by 2050. Living with cancer puts exceptional burdens on individuals and families during treatment and survivorship, including how they navigate their relationships with one another. One role that a member of a support network may enact is that of a surrogate seeker, who seeks information in an informal capacity on behalf of others. Individuals with cancer and surrogate seekers often use the internet to learn about cancer, but differences in their skills and strategies have received little empirical attention.

Objective

This study aimed to examine the eHealth literacy of individuals with cancer and surrogate information seekers, including an investigation of how each group evaluates the credibility of web-based cancer information. As a secondary aim, we sought to explore the differences that exist between individuals with cancer and surrogate seekers pertaining to eHealth literacies and sociodemographic contexts.

Methods

Between October 2019 and January 2020, we conducted a web-based survey of 282 individuals with cancer (n=185) and surrogate seekers (n=97). We used hierarchical linear regression analyses to explore differences in functional, communicative, critical, and translational eHealth literacy between individuals with cancer and surrogate seekers using the Transactional eHealth Literacy Instrument. Using a convergent, parallel mixed methods design, we also conducted a thematic content analysis of an open-ended survey response to qualitatively examine how each group evaluates web-based cancer information.

Results

eHealth literacy scores did not differ between individuals with cancer and surrogate seekers, even after adjusting for sociodemographic variables. Individuals with cancer and surrogate seekers consider the credibility of web-based cancer information based on its channel (eg, National Institutes of Health). However, in evaluating web-based information, surrogate seekers were more likely than individuals with cancer to consider the presence and quality of scientific references supporting the information. Individuals with cancer were more likely than surrogate seekers to cross-reference other websites and web-based sources to establish consensus.

Conclusions

Web-based cancer information accessibility and evaluation procedures differ among individuals with cancer and surrogate seekers and should be considered in future efforts to design web-based cancer education interventions. Future studies may also benefit from more stratified recruitment approaches and account for additional contextual factors to better understand the unique circumstances experienced within this population.
Physical Therapists’ Knowledge and Attitudes Regarding Artificial Intelligence Applications in Health Care and Rehabilitation: Cross-sectional Study
Authors: Alsobhi Mashael , Khan Fayaz , Chevidikunnan Mohamed Faisal , Basuodan Reem , Shawli Lama , Neamatallah Ziyad
Published: September 2022

Background

The use of artificial intelligence (AI) in the field of rehabilitation is growing rapidly. Therefore, there is a need to understand how physical therapists (PTs) perceive AI technologies in clinical practice.

Objective

This study aimed to investigate the knowledge and attitude of PTs regarding AI applications in rehabilitation based on multiple explanatory factors.

Methods

A web-based Google Form survey, which was divided into 4 sections, was used to collect the data. A total of 317 PTs participated voluntarily in the study.

Results

The PTs’ knowledge about AI applications in rehabilitation was lower than their knowledge about AI in general. We found a statistically significant difference in the PTs’ knowledge regarding AI applications in the rehabilitation field based on sex (odds ratio [OR] 2.43, 95% CI 1.53-3.87; P<.001). In addition, experience (OR 1.79, 95% CI 1.11-2.87; P=.02) and educational qualification (OR 1.68, 95% CI 1.05-2.70; P=.03) were found to be significant predictors of knowledge about AI applications. PTs who work in the nonacademic sector and who had <10 years of experience had positive attitudes regarding AI.

Conclusions

AI technologies have been integrated into many physical therapy practices through the automation of clinical tasks. Therefore, PTs are encouraged to take advantage of the widespread development of AI technologies and enrich their knowledge about, and enhance their practice with, AI applications.
Analysis of Dermatology Content by Top Influencers on Twitter and Their Academic Impact: Cross-Sectional Study (Preprint)
Authors: Szeto Mindy D , Mamo Andrina V , Kamel Kevin , Olayinka Jadesola T , Patel Payal M , Hamp Austin , Anderson Jarett , Kim Lori S , Yemc Madeleine G , Sivesind Torunn E , Dellavalle Robert P
Published: September 2022

UNSTRUCTURED
The societal impact of early intensified treatment in patients with type 2 diabetes mellitus
Authors: Tsotra Foteini , Kappel Mathias , Peristeris Platon , Bader Giovanni , Levi Eva , Lister Nicola , Malhotra Ankur , Ostwald Dennis A
Published: September 2022

Aim:The current study estimates the societal impact of early intensified treatment compared with initial monotherapy with subsequent treatment intensification in newly diagnosed adults with type 2 diabetes mellitus in Mexico.Methods:An individual patient-level simulation and a static cohort model were employed to simulate the treatment pathway and the probability of experiencing complications of diabetes. The avoided number of events was translated into avoided productivity losses, which were monetized using wages.Results:Patients on early intensified treatment experienced approximately 13,000 fewer complication events over 10 years. This was translated into a societal impact of $54 million (USD).Conclusion:Early treatment intensification is likely to be of particular benefit to health outcomes and productivity losses.
Machinability and Chip Morphology Study of Inconel 740H and Haynes 282 for Advanced-Ultra Supercritical Applications
Authors: P A Ramakrishnan. , Ramesh Ajith , Sumesh C. S.
Published: September 2022

Abstract: High speed machining of Nickel based alloys has gained a lot of research interest since the last decade owing to their applications in areas like power generation, aerospace, marine propulsion, and nuclear reactors. For the realization of an advanced ultra-supercritical (A-USC) thermal plant, operating at service temperatures of about 700 to 760oC and pressures of around 24 MPa, the use of Nickel-based super alloys is indispensable. Some these parts used for the application may be required to be machined before use, although the machinability of these materials is relatively poor. Chip morphological studies are performed for better understanding of cutting force and surface finish of the alloys. In this work, authors have tried to study the effect of machining parameters like cutting speed, feed rate, rake angle, and nose radius on chip morphology like peak height, valley height, tooth height, tooth pitch, and segmentation frequency. The results of chip morphology studies indicate the need for saw tooth chips for better machining. Accordingly, Inconel 740H is found to have better machinability than Haynes 282 for the used range of machining parameters. Moreover, higher cutting speeds, lower feed rates, and positive rake angles are found to yield optimum conditions for an improved machinability
Study the Behavior of Box Type Minor Bridge or Vehicular Under Pass When Subjected to Different Combination of Loads in Terms of Bending Moment and Shear Force Variations
Authors: Pilania Hardeep , Parihar Rajeev Singh , Jha Abhay Kumar , Kumar Barun , Misra Rajesh
Published: September 2022

Abstract: Predicted Earth Pressure, Stresses, Moments, Shear forces under the action of load combinations at the location of VUP are presented for symmetrical and unsymmetrical live loading conditions. Furthermore, predicted bending moment distributions around the RCC single cell Box VUP are presented for various loading conditions. The design considerations, ULS and SLS check after the design structure analyses with excel calculations and as per IS and IRC codes. In additions, The shear force distributions around the RCC single cell Box VUP are presented for various loading conditions.
Confiscation Of Assets In Economic Crime
Authors: Hapsari Sulvia Triana , Madjid Abdul , Aprilianda Nurini
Published: September 2022

Corruption is an extraordinary crime so the punishment is the Primum Remedium. Economic Analysis of Law can be used to increase the efficiency of handling corruption crimes (TPK) to provide a level of efficiency and a deterrent effect. The formulation of the problem in this research is how is the economic analysis of law in maximizing the looted assets from the crime of corruption? This research is based on judicial normative. The data were collected using the search method and literature review. Conclusion Based on the economic analysis of law, the shift in the orientation of punishment in criminal acts of corruption from corporal punishment to a combination of corporal punishment, large fines, confiscation of assets, and impoverishment of perpetrators of criminal acts of corruption without diminishing the meaning of corporal punishment shows effectiveness and efficiency and will increase the deterrent effect for the perpetrator.
Survivability of reinforced concrete frames of multi-storey buildings with complex stress elements
Authors: Kolchunov Vitaly I. , Moskovtseva Violetta S.
Published: September 2022

Experimental determination of the parameters of the force resistance of reinforced concrete structures aimed at protecting them from emergency beyond design impacts is an important direction in improving the safety of buildings and structures. In this connection, the purpose of the study was an experimental assessment of the deformation parameters in the complexly stressed elements of reinforced concrete frames under special impact in the form of a sudden column removal. Experimental studies were carried out for two frames, one of which was tested when removing the middle column, the second - when removing the extreme. Experimental two-span structures of reinforced concrete frames are designed with three floors in height, reinforcement was made with spatial reinforcing cages that provide resistance to torsion with bending. The results of experimental and theoretical studies of reinforced concrete frame structures under special influences and an assessment of displacements, cracking and destruction of the considered complex-stressed structural elements under such influences are presented. It is established that the type of stress state, the formation and width of crack opening significantly affect the dissipative properties of the structural system.
Rigidity, adhesion and delamination of the coating in the “substrate - coating” system
Authors: Yakupov Samat N. , Gubaidullin Ruslan I.
Published: September 2022

Protective coatings are widely used in all branches of production and life. The necessary qualities of coatings are provided by developing complex thin-layer compositions. The complexity of the structure of the coating also arises during operation as a result of the influence of the environment, physical fields, human factor. Many coatings are initially formed directly on the surfaces of structures with initially complex geometry. At the same time, a number of smart coatings, along with a complex structure, change their physical and mechanical properties when triggered. When choosing a coating, adhesive and technology for its application, questions arise related to determining their necessary geometric and physical parameters, assessing their mechanical properties and service life depending on the environment and physical fields, etc. This requires a reliable research tool. In the review, based on well-known publications and patents for the invention, the following are noted: methods for studying the mechanical properties of decomposable and non-decomposable coatings; methods for determining adhesion - the adhesion strength of the coating to the substrate; methods for studying the delamination of constituent elements and delamination of the coating from the substrate. Attention is focused on effective experimental and theoretical methods for assessing the mechanical properties of the coating and adhesive on flat and non-planar surfaces, as well as on some relevant results.
Comparative study of finite element methods of calculation of ribbed reinforced concrete floors
Authors: Nikitin Konstantin E. , Kirsanov Oleg A.
Published: September 2022

The paper presents the results of a comparative study of several finite element models of ribbed reinforced concrete solid floors. Using the example of a solid slab with infrequent ribs arranged along a grid of columns, three models frequently used in computational practice are analyzed. Those models include both rods and thin-walled elements. In the first model, the plate and its ribs are considered separately, within the framework of the decomposition scheme of the structure. The second model contains plate finite elements and the rod finite elements of the ribs connected to each other. The third model consists entirely of thin-walled finite elements that model both the plate and the floor ribs. The ribbed floor is also considered in the formulation of the problem within the framework of the theory of elasticity. The floor is represented in the form of rigidly connected solid bodies of ribs and plates. Reinforcement rods inside the concrete massive are included in the model as separate solid bodies. This model serves as a benchmark for assessing the accuracy of the obtained results. Its calculation is performed in the FEM application Ansys. The paper compares the results of calculations performed using various models. A conclusion is made about the accuracy of the obtained results. A significant difference between the proposed work and similar studies devoted to the selection of the best design schemes of ribbed slab of floor is the consideration of the influence of reinforcement on the behavior of the structure.
Efficiency of early spring feeding of winter wheat complex fertilizers on light podzolic soil in Poland
Authors: Blashik Roman M. , Nosov Vladimir V. , Peliy Alexandr F.
Published: September 2022

Field experiments were carried out on sandy loamy podzolic soil in the Łdź Voivodship (Wieluń commune, Masłowice parish) at the Experimental Station of the Polish Research Variety Testing Center, to study the effect of various winter wheat feeding systems with an intensive cultivation system on yield and grain quality indicators. The soil before conducting the experiments was characterized by a neutral reaction of the soil environment, a very high level of mobile phosphorus, and an average content of mobile potassium in 2017 and 2019, and high availability in 2018. The initial level of nitrate nitrogen in the soil was medium in 2017 and high in 2018 and 2019. The podzolic soils of the region, with a light granulometric composition, often have a low supply of sulfur available to plants. With a low content of humus in such soils, there is a small reserve of sulfur in organic form, and therefore, variants with sulfur-containing fertilizers were included in the intensive technology of winter wheat cultivation. Weather conditions of the growing seasons 2017-2018, 2018-2019 and 2019-2020 differed by an insufficient amount of atmospheric precipitation during the growth stages critical for grain formation. The yield of winter wheat grain in all years of research was maximum in variant 3 with the use of ammonium nitrate and complex sulfur-containing fertilizer Apaviva NPK(S) 15:15:15(10) as top dressing. The yield increase resulted from the autumn phosphorus-potassium application (double superphosphate and potassium chloride) was 25, 34 and 30 % in 2018, 2019 and 2020, respectively. The maximum grain yield of winter wheat in the experiment of 6.93 t/ha was obtained in variant 3 in 2019. Such a system of winter wheat top dressing provided a stable high additional income.
Cow reproduction rates with varying inbreeding degrees
Authors: Rudenko Oksana V.
Published: September 2022

The evaluation of the breeding work results carried out, the identification of optimal systems for the animals selection, including related ones, have always been relevant. The purpose was to study the influence of various inbreeding degrees on reproductive abilities and their selection and genetic parameters in Holstein cows. The research was carried out on the basis of Pushkinskoe Breeding Plant, Nizhny Novgorod region. At the earliest age, heifers were inseminated in the group with recent inbreeding (14.87 months), for this reason they had the lowest weight at the first insemination - 4 25.7 kg. Cows in the group with recent inbreeding had the shortest service period (108.9 days), the longest service period was in the group with close inbreeding (152.6 days). The variability of live weight during the first insemination and fertilization in all groups was at a low level (Cv = 5,228,25 %). The duration of the service period after first lactation in all groups, except for the group of close inbreeding, had a variation of about 45 %, in the group with close inbreeding it was 1.5 times higher. Despite its small number, the group of close inbreeding turned out to be the most variable in all indicators. An increase in the age of the first fertilization of heifers in the group of close inbreeding leads to an increase in the duration of the service period (r = 0.335). However, there is practically no connection between these indicators in the other groups. Many of the studied indicators had a weak positive or negative relationship with each other. Among the resulting young, more than half were heifers, in groups with different inbreeding degrees this indicator varied from 63.3 to 66.7 %, in the group with outbred animals it was 69.4 %. Twins were registered 2 times and only in the group with a recent inbreeding degree. Stillbirth in all groups was at a fairly low level - 5 .76.7 %, in the group with a close inbreeding degree no cases of stillborn calves were detected. The birth of calves with congenital deformities and pathologies from related mating was not observed. Thus, in the conducted studies, inbreeding had no negative impact on the cows reproductive qualities even to a close degree.
Funciones biológicas: una revisión crítica y una propuesta
Authors: Alarcón Nicolás
Published: September 2022

La presente investigación tiene como objetivo proponer una nueva teoría para dar cuenta de las funciones de los objetos biológicos. Para ello, mostraré en qué fallan las teorías más aceptadas de funciones biológicas, para luego proponer una nueva alternativa que supera los contraejemplos dados. La investigación está dividida en las siguientes preguntas: i) apelando a diversos contraejemplos, señalaré que no hay una teoría robusta capaz de dar cuenta del fenómeno; finalmente ii) daré una teoría provisional/operacional mínima, la cual permite seguir incorporando la dimensión funcional de los rasgos.
Effect of Copper Sulfate On Hematological and Histological Parameters of Freshwater Fish Oreochromis niloticus at Various Sublethal Concentration
Authors: Sasikumar S. , Leon J. Prakash Sahaya
Published: September 2022

Heavy metals pollution is a great environmental problem in recent years throughout the world. Various activities such as domestic, anthropogenic activities, volcanic eruptions and industrial activities which increase their level of heavy metals concentration into the environment. Copper sulfate is used as an algaecide and fungicide in the fields of agriculture and aquaculture being discharged into water bodies and it can affect the aquatic organisms, especially fishes. The present study deals with the effect of copper sulfate on various hematological parameters of the experimental fish Oreochromis niloticus. Oreochromis niloticus is an important freshwater fish in commercial aquaculture. Fish is a significant food component of human food. Fish are the suitable bio-indicators of heavy metal contamination. Heavy metals are oxidative stress inducers in fish and can reflect aquatic contamination. The Objective of the present study was to analyze the hematological effects of heavy metal CuSO4 on the freshwater fish O.niloticus. The LC50 value of copper sulfate found to be 39.2 mg/L. The fish Oreochromis niloticus were experimented for the different sub lethal concentrations of 1/10, 1/20 and 1/30 of copper sulfate for the period of 30 days to get hematological changes. At the end of the experiment the result shows that the Red Blood Cell (RBC) count and the percentage of hemoglobin (Hb) were significantly decreased as the sub-lethal concentration of heavy metal Copper sulfate increased, while the level of WBC, MCV and MCH significantly increased. The effect of copper sulfate was observed by histopathological investigation of gill and liver of treated fish. The aim of present study is to investigate the hematological and histopathological effects of copper sulfate for the period of 30 days at various sublethal concentration in various tissues of the freshwater fish O. niloticus.Dietary data were collected in detail through face-to-face interview on tilapia O.niloticus consumption. Intake of fish (g) was computed. Statistical analyses were conducted using SPSS software for Windows and all tests were considered significant at p<0:05.
Harlequin Ichthyosis: a case report and literature review.
Authors: Shrestha Abhigan , biswas prince , shrestha sajina , shrestha shumneva , riyaz romana , Nawaz Muhammad Hassnain , hossainy Labiba
Published: September 2022

Harlequin Ichthyosis is a rare autosomal recessive disorder occurring in
1: 3,000,000 birth characterized by thick keratin skin with scaly
appearance. Preterm deliveries, early marriage and consanguinity of
marriage are some risk factors. Antenatal checkup of DNA for ABCA12
mutation helps in diagnosis but USG in places where not available.
OPA1 Regulates Lipid Metabolism and Cold-Induced Browning of White Adipose Tissue in Mice
Authors: Pereira Renata O. , Olvera Angela C. , Marti Alex , Fang Shi , White Jeffrey R. , Westphal Michael , Hewezi Rana , AshShareef Salma T. , García-Peña Luis Miguel , Koneru Jivan , Potthoff Matthew J. , Abel E. Dale
Published: September 2022

Mitochondria play a vital role in white adipose tissue (WAT) homeostasis including adipogenesis, fatty acid synthesis, and lipolysis. We recently reported that the mitochondrial fusion protein optic atrophy 1 (OPA1) is required for induction of fatty acid oxidation and thermogenic activation in brown adipocytes. In the current study we investigated the role of OPA1 in WAT function in vivo. We generated mice with constitutive or inducible knockout of OPA1 selectively in adipocytes. Studies were conducted under baseline conditions, at thermoneutrality, following high-fat feeding or during cold exposure. OPA1 deficiency reduced mitochondrial respiratory capacity in white adipocytes, impaired lipolytic signaling, repressed expression of de novo lipogenesis and triglyceride synthesis pathways, and promoted adipose tissue senescence and inflammation. Reduced WAT mass was associated with hepatic triglycerides accumulation and glucose intolerance. Moreover, mice deficient for OPA1 in adipocytes had impaired adaptive thermogenesis and reduced cold-induced browning of subcutaneous WAT and were completely resistant to diet-induced obesity. In conclusion, OPA1 expression and function in adipocytes are essential for adipose tissue expansion, lipid biosynthesis, and fatty acid mobilization of WAT and brown adipocytes and for thermogenic activation of brown and beige adipocytes.
OPA1 Regulates Lipid Metabolism and Cold-Induced Browning of White Adipose Tissue in Mice
Authors: Pereira Renata O. , Olvera Angela C. , Marti Alex , Fang Shi , White Jeffrey R. , Westphal Michael , Hewezi Rana , AshShareef Salma T. , Pena Luis Miguel Garcia , Koneru Jivan , Potthoff Matthew J. , Abel E. Dale
Published: September 2022

Mitochondria play a vital role in white adipose tissue homeostasis including adipogenesis, fatty acid synthesis, and lipolysis. We recently reported that the mitochondrial fusion protein optic atrophy 1 (OPA1) is required for induction of fatty acid oxidation and thermogenic activation in brown adipocytes. The present study investigated the role of OPA1 in white adipose tissue (WAT) function in vivo. We generated mice with constitutive or inducible knockout of OPA1 selectively in adipocytes. Studies were conducted under baseline conditions, at thermoneutrality, following high-fat feeding or during cold exposure. OPA1 deficiency reduced mitochondrial respiratory capacity in white adipocytes, impaired lipolytic signaling, repressed expression of de novo lipogenesis and triglyceride synthesis pathways and promoted adipose tissue senescence and inflammation. Reduced WAT mass was associated with hepatic triglycerides accumulation and glucose intolerance. Moreover, mice deficient for OPA1 in adipocytes had impaired adaptive thermogenesis, reduced cold-induced browning of sub-cutaneous WAT, and were completely resistant to diet-induced obesity. In conclusion, OPA1 expression and function in adipocytes is essential for adipose tissue expansion, lipid biosynthesis and fatty acid mobilization of WAT and brown adipocytes, and for thermogenic activation of brown and beige adipocytes. 
The Image of Islam in Russia
Authors: Endresen Cecilie
Published: September 2022

Kapitlene i Greg Simons (red.), The Image of Islam in Russia drøfter ulike sider av forholdet mellom muslimer og staten i Russland siden 1990-årene og holder høy akademisk standard. Boken er et opptrykk av to-tre år gamle utgaver av tidsskriftet Religion, State and Society.
The chapters in Greg Simons (ed.), The Image of Islam in Russia discuss various aspects of Muslim–state relations in Putin’s Russia and are of high academic quality. This collected volume is a massive reprint of 2 to 3-year-old issues of the journal Religion, State and Society.
PRINCIPAIS ASSUNTOS DE AUDITORIA: A DIVULGAÇÃO AINDA É COMUNICATIVA APÓS TRÊS ANOS DE APLICAÇÃO DA NBC TA 701?
Authors: Colares Ana Carolina Vasconcelos , Pinheiro Laura Edith Taboada , Silva Jaqueline Nunes da
Published: September 2022

A pesquisa analisou se os relatórios de auditoria apresentaram novidades nas informações divulgadas na seção intitulada ‘Principais Assuntos de Auditoria’ (PAA) após os três primeiros anos de aplicação da norma NBC TA 701. Desta forma, analisaram-se 840 relatórios de auditoria de 280 empresas brasileiras de capital aberto, sendo identificados 2.244 PAA, e divulgada uma média total de 2,67 PAA por relatório no período analisados, sendo ainda constatada uma redução de 8% na quantidade de PAA divulgados. Os resultados mostraram que de forma geral, os auditores têm divulgado menos PAA ao longo da implementação da norma, sendo constatada uma taxa de repetição média de 52,5% dos assuntos, considerada significativa e que pode afetar negativamente a qualidade da comunicação dos auditores aos seus usuários. Apesar do resultado, não foi possível constatar que a troca ou manutenção do auditor tenha influência sobre a decisão de repetir ou não os assuntos de auditoria.
FERRAMENTA DE ANÁLISE DE RISCO UTILIZANDO O CICLO FINANCEIRO PARA EMPRESAS DE AGRONEGÓCIOS LISTADAS NA BRASIL, BOLSA, BALCÃO (B3)
Authors: Lima Stella Santana de , Vilchiez Israel Gomes , Oliveira Eduardo Cezar de
Published: September 2022

Este artigo tem como objetivo o desenvolvimento de uma ferramenta para analisar risco dentro das empresas de agronegócio brasileiro, tendo como condutor fatores segundo a literatura, as entradas e saídas que compõem o ciclo financeiro das empresas, detalhado no referencial teórico. O estudo tem caráter quantitativo e utilizou o método de revisão de literatura para executar os indicadores e desenvolver a ferramenta. O estudo trouxe o resultado de prazo médio de pagamento, prazo médio de recebimento e ciclo operacional das empresas estruturando, assim um farol de risco sobre o ciclo financeiro das empresas da amostra. A contribuição do estudo está na junção de fatores contábeis unidos a um mecanismo relevante de mensuração de risco para o financeiro das empresas.
PRONUNCIAMENTO TÉCNICO CPC 33 (R1) E ANÁLISE DE SENSIBILIDADE DAS PREMISSAS ATUARIAIS NAS EMPRESAS DO SETOR ELÉTRICO
Authors: Garcia Downes Lilian Cristina , Lopes da Silva Fabiana , Mitiyo Yamamoto Marina
Published: September 2022

O objetivo do estudo foi identificar o impacto potencial nas demonstrações contábeis das empresas do setor elétrico, patrocinadoras de planos de benefícios previdenciários na modalidade benefício definido (BD), decorrente da análise de sensibilidade das premissas atuariais. Para tanto, selecionou-se uma amostra de 26 empresas listadas na B3, na qual foram analisadas as notas explicativas do exercício social encerrado em 31/12/2018. Com base nas análises efetuadas à luz do Pronunciamento Técnico CPC 33 (R1), foi verificado que as premissas significativas mais utilizadas na análise de sensibilidade foram: tábua de mortalidade (53,85%), taxa de desconto (100,00%) e crescimento salarial (23,08%). Com base nos valores informados na análise de sensibilidade, foram calculados os possíveis impactos da alteração de premissas no valor presente da obrigação atuarial das instituições selecionadas.
COMPORTAMENTO DO COEFICIENTE BETA DAS AÇÕES BRASILEIRAS NO PERÍODO DA CRISE GERADA PELA PANDEMIA DA COVID-19
Authors: Costa Resende Kallienny , Willrich Sales George André
Published: September 2022

A análise do risco e retorno desempenha um importante papel na tomada de decisão de um investimento. O mercado é dinâmico e pode ser alterado por diversos fatores, incluindo crises econômicas. Em 2020 o mundo começou a enfrentar a pandemia da Covid-19 que causou fortes alterações no ambiente econômico. Desta forma, o objetivo do estudo foi avaliar qual efeito que esta crise teve sobre o comportamento do coeficiente beta das ações listadas na bolsa brasileira. Para isso, foi utilizado o teste de Kruskal-Wallis para comparar a média dos coeficientes de 146 companhias abertas entre os anos de 2017 a 2020. Os resultados mostraram que entre os anos de 2017 a 2019 houve estabilidade no coeficiente, contudo, no ano de 2020 houve um aumento significativo do beta, corroborando com a hipótese de que em períodos de crise o risco do mercado acionário tende aumentar. Dentre os setores analisados, apenas comunicações, materiais básicos e saúde não tiveram aumento significativo do risco em 2020. Os resultados mostraram também que em todos os anos estudados existiu diferença entre os trimestres, o que significa que o risco se altera ao longo do ano. Por fim, pode-se concluir também que as empresas enquadradas dentro do Índice de Sustentabilidade Empresarial não apresentaram modificações nas médias do coeficiente beta ao longo do período estudado.
Risk Management in Oil and Gas Field Development Project with Marginal Resources: A Case in Mature Field in East Kalimantan
Authors: Saptarini Dyah A. , Nainggolan Yunieta A.
Published: September 2022

The oil and gas industry and risks are very related to each other. There are several risks known in this industry, from economic risks, political risks, environmental and safety risks, up to geological risks itself. Because oil and gas are a non-renewable source of energy, the more mature an oil and gas field is, the risks for the company to develop a project investment may be lower and higher at the same time. Entering its declining phase, PT MNO who is trusted to operate an ex-termination oil and gas field in East Kalimantan which has been producing for almost 50 years, is required to find a way to survive until end of contract in 2037 by developing the remaining hydrocarbon resources which become more and more marginal. The project development is proposed as a bundling to allow flexibility during execution phase in selecting the well candidates based on recent data acquired from previous wells drilled, hence reducing the risks. Field Development Package (FDP) 2.3 is prepared as part of PT MNO long term plan and commitment after receiving incentive from Government of Indonesia in 2021. According to the Company Guideline, a risk register is mandatory to be developed since beginning of project which covers risks identification, risks analysis, and risks evaluation. The project team is also responsible to define risks treatment to manage the risks borne by the project. This is in line with the requirement for Good Corporate Governance, where risk management is introduced since beginning of the project life-cycle. This study covers the risk assessment on the basis of selected project scope which has been validated technically. The risk assessment will determine the major risks in FDP 2.3 considering available historical data of oil price, drilling cost realization, and facility cost realization. These risks need to be monitored to ensure the FDP 2.3 will create value for the shareholder as per plan or avoid loss at the minimum. The most important risks concluded in this study is oil price lower than economic assumption, production target not achieved, and no fix gas sales contract to absorb production. The company may focus in these risks for the risk management of future project development.
Regional Science, Location and Economic Theory: Thoughts and Discussions about Development
Authors: Castro Hélder Uzêda
Published: September 2022

This theoretical discussion intends to reinforce some of the main aspects of Regional Science, discussing the spatial issue through studies on geographic location, and how these relate to important economic theories. From the rescue of the thinking of classic authors of Regional Science, emphasizing spatial and location issues, and of Economics with a focus on development, using the resource of bibliometric research of periods of contemporary history, it was possible to review thoughts and theories and emphasize the importance of connecting factors present in economic and geographical studies. The region and the territory were approached in an attempt to demonstrate them as an environment for important research phenomena. It was noted that phenomena linked to Regional Economic Development have re-emerged in recent years as a global trend, considering internal movements due to the health crisis (COVID-19) and global conflicts (i.e. Russia x Ukraine), but they are still poorly studied. The scientific contribution lies in strengthening the relationship between what is discussed in academia and what happens in society.
The Use of Social-Media and IT Application Tools for Teaching in Ghanaian Universities: Case of University of Cape Coast, Ghana
Authors: Asomah Richard Kyere , Assamah Gabriel , Commey-Mintah Priscilla , Boateng Francis Ohene
Published: September 2022

The use of social media and IT application tools as an alternative pedagogical approach in higher educational institutions of learning cannot be compromised. Considering their incalculable advantages especially, in these times of the COVID-19 pandemic where closure of schools characterised some of the mitigating factors which wedged pedagogy. Nonetheless, quite a few institutions have taken advantage of these technologically inclined resources to facilitate teaching and learning. Therefore, this study explores the perceived usage of social media outlets and IT application tools in the University of Cape Coast (UCC) as a means of pedagogy by the Academic Staff. The study employed a cross-sectional survey as result of which 102 Academic Staff were sampled. The findings disclosed that the use of social media (i.e., Twitter), online collaborative tool (i.e., Google Hangouts) as a means of pedagogy is conspicuously absent among the teaching staff. Whiles some IT application tools (i.e., Dropbox, Google Drive, OneDrive) were hardly used in the classroom context, although the participants revealed possessing the skills in the use of such social media outlets and the IT application tools at their individual level. However, the use of Presentation tools (i.e., Microsoft PowerPoint), Spreadsheets (i.e., Microsoft Excel) and Word Processing (i.e., Microsoft Word) were mostly used to facilitate teaching and learning. The study recommends the adoption and enforcement of these resources by the management of the university. Taking into cognizance, the numerical strength of the yearly enrollment of students into the University vis a viz its limited infrastructure.
Prediction of Rheological Properties of Recirculating Water-Based Drilling Mud in Geothermal Exploration using Artificial Neural Networks with Tensor Flow
Authors: Mengich Hillary , Kabugu Michael , Ondiaka Mary Nelima
Published: September 2022

Pipe sticking in drilling operations occurs by mechanical and differential forces caused by the loss in circulation of drilling fluids or muds. Rheological properties of recirculating drilling muds (RDMs) determine the drilling hydraulics and hole cleaning effectiveness. Uncertainty in real-time data on the rheological properties of RDMs challenges estimation of potential pipe sticking problems, a problem that can be improved using machine learning methods. This study reports first-time application of a supervised artificial neural networks (ANN) algorithm with TensorFlow to estimate plastic viscosity (PV), apparent viscosity (AV), yield point (YP), flow consistency index (k), and flow behavior index (n), five rheological properties of recirculating water-based drilling mud (R-WBDM). Model input variables were density (MD), marsh funnel viscosity (MFV), and percent solids content (% S) of R-WBDM. Model performance was tested using the root mean square error (RMSE) and coefficient of determination (R2) methods. Sensitivity analysis demonstrated the strength of each predictor variable. Five optimal models showed good generalization capability in estimating the n, k, PV, AV, and YP with RMSE of 0.022, 0.270, 7.890, 8.870, and 10.149, and R2 of 0.995, 0.956, 0.756, 0.724, and 0.701 in a similar order, respectively. High sensitivity was observed in PV, AV, YP, and k models, and n-model, to changes in MFV (0.615) and % S (0.067), respectively. Results show the potential use of ANN with TensorFlow to support decision-making in geothermal drilling engineering on pipe sticking problems using easy-to-determine physical properties as predictor variables.
Signing a Pact with the Devil: Hermeticism in Shakespeare’s Macbeth
Authors: Mouelhi Oumeima
Published: September 2022

The Renaissance was an enlightening period in which new ethics and world views emerged. A move from a zealous Christian creed to an interest in worldly pleasures and the cult of the self and beauty were preached.
Running parallel to these big discoveries and giant progress in different spheres, Renaissance England still bore the vestige of credence in what is considered as “weird” to contemporary man as ghosts, apparitions, and witches. Magic continued to be evoked and practices of witchcraft bore its fruition back then. What is noticeable is that despite the overall ambiance of a prevailing rational mood and thirst for the palpable, Hermeticism had a strongly felt presence in the new social milieu.
This paper seeks to turn an analytical eye on hermeticism that was vividly present during Shakespeare’s time through his tragedy, Macbeth. Above all, it sheds light on the evil practices that were conquering the Elizabethans despite the progressive era that the nation was witnessing.