bluuebunny/crossref_metadata_2025 huggingface dataset:
Association between γ-Glutamyltransferase and Head and Neck Cancer in Korean Population: A National Population-Based Study
Authors: Lee Dong-Hyun , Kim Choung-Soo , Park Jun-Ook , Nam Inn-Chul , Park Sung Joon , Kim Hyun-Bum , Han Kyungdo , Joo Young-Hoon
Published: August 2022

Background:

Gamma-glutamyltransferase (GGT) is positively associated with several cancer types. The objective of this study was to investigate the association between GGT and head and neck cancer (HNC) incidence in a cohort of 10 million people, considering effects of smoking and alcohol consumption.

Methods:

All data used in this study were obtained from the Korean National Health Insurance Service database. We analyzed subjects who underwent health check-ups in 2009 and monitored them until 2018 (n = 9,597,952). Using proportional hazards models, quartiles of GGT as independent predictors for HNC incidence were evaluated.

Results:

The overall incidence of HNC increased in the highest quartile [r-GPT ≥ 40 U/L; HR, 1.452; 95% confidence interval (CI), 1.354–1.557]. Among HNC cases, the HR for hypopharyngeal cancer (HR, 2.364; 95% CI, 1.818–3.074) was significantly higher. HRs for HNC (larynx, sino-nasal, oropharynx, oral cavity, and nasopharynx, except salivary glands) were also significant.

Conclusions:

Elevated GGT was associated with the risk of some types of HNCs, such as hypopharyngeal, laryngeal, sinonasal, oropharyngeal, oral cavity, and nasopharyngeal cancer.

Impact:

Results of this study have implications for etiologic investigations and preventive strategies.
Botulinum Toxin as an Effective Treatment for Trigeminal Neuralgia in Surgical Practices
Authors: Tangney Thomas , Heydari Ehsaun S. , Sheldon Breanna L. , Shetty Amit , Argoff Charles E. , Khazen Olga , Pilitsis Julie G.
Published: August 2022

Background: Trigeminal neuralgia (TN) is a common cause of craniofacial pain with many medical and surgical therapies, all of which are imperfect. We examine the use of botulinum toxin type-A (BTX-A) as an intermediary approach in surgical practices. Methods: We retrospectively identified TN patients seen by both pain neurology and neurosurgery at our center. Demographics were collected. Pain intensity was assessed using the numerical rating scale (NRS) and compared from baseline to after BTX-A treatment via paired t test. Responder status was assessed, and success of BTX-A was determined for each cohort. Doses of common medications were compared between baseline visit and the most recent BTX-A administration visit. Results: Thirty-one patients underwent BTX-A therapy for TN, 24 (77%) female and 7 (23%) male. Mean age was 62.5 ± 3.1 years and 29 (94%) identified as white. When divided into cohorts according to indication, 11 (35%) failed prior TN surgery, 9 (29%) either declined surgery or were poor surgical candidates, 4 (13%) had multiple sclerosis, 4 (13%) had trigeminal neuropathic pain, and 3 (10%) had atypical TN with pain in additional dermatomes outside the trigeminal distribution. Significant reductions in NRS from baseline to following initial BTX-A treatment were seen in the declined/high risk for surgery (p = 0.004) and those who failed prior TN surgery (p = 0.035) groups. No significant variation in demographics was found between any two groups (p > 0.05 for all). Finally, there was no significant reduction in total daily dose of gabapentin, carbamazepine, oxcarbazepine, baclofen, or lamotrigine in BTX-A responders (p > 0.05 for all). Discussion: Indication is an important predictor for BTX-A, with classical TN patients exhibiting the highest response rates. This research highlights the viability of BTX-A as an important tool in the arsenal of providers seeking to treat TN in a minimally invasive manner.
Associations Between Soluble fms‐Like Tyrosine Kinase‐1 and Placental Growth Factor and Disease Severity Among Women With Preterm Eclampsia and Preeclampsia
Authors: Hastie Roxanne , Bergman Lina , Walker Susan P. , Kaitu'u‐Lino Tu'uhevaha , Hannan Natalie J. , Brownfoot Fiona , Schell Sonja , Harper Alesia , Cannon Ping , Cluver Catherine A. , Tong Stephen
Published: August 2022

Background

The angiogenic factors soluble fms‐like tyrosine kinase‐1 (sFlt‐1) and placental growth factor (PlGF) are postulated to be pathogenic disease drivers of preeclampsia. If true, then circulating levels should become more deranged with increasing disease severity.

Methods and Results

We investigated the association between circulating sFlt‐1 and PlGF levels and severe adverse maternal outcomes among 348 women with preeclampsia. Compared with 125 women with preeclampsia without severe features, 25 women with preeclampsia and any of hemolysis, elevated liver enzymes, low platelet count syndrome, disseminated intravascular coagulation, or severe renal involvement had sFlt‐1 levels that were 2.63‐fold higher (95% CI, 1.81–3.82), sFlt‐1/PlGF levels that were 10.07‐fold higher (95% CI, 5.36–18.91) and PlGF levels that were 74% lower (adjusted fold change, 0.26 [95% CI, 0.18–0.39]). Compared with 125 women with preeclampsia without severe features, 37 with eclampsia had sFlt‐1 levels that were 2‐fold higher (2.02 [95% CI, 1.32–3.09]), sFlt‐1/PIGF levels that were 4.71‐fold higher (95% CI, 2.30–9.66) and PIGF levels that were 63% lower (0.43‐fold change [95% CI, 0.27–0.68]). Compared with those without severe features, preeclampsia with severe hypertension (n=146) was also associated with altered angiogenic levels (sFlt‐1, 1.71‐fold change [95% CI, 1.39–2.11]; sFlt/PlGF, 2.91 [95% CI, 2.04–4.15]; PlGF, 0.59 [95%CI 0.47–0.74]). We also found that sFlt‐1 and PlGF levels were altered by the number of maternal complications experienced.

Conclusions

Further angiogenic imbalance among women with preeclampsia is likely a pathogenic disease driver responsible for the life‐threatening maternal complications.
Coronary Artery Calcium Score to Refine the Use of PCSK9i in Asymptomatic Individuals: A Multicohort Study
Authors: Cainzos‐Achirica Miguel , Quispe Renato , Mszar Reed , Dudum Ramzi , Al Rifai Mahmoud , Erbel Raimund , Stang Andreas , Jöckel Karl‐Heinz , Lehmann Nils , Schramm Sara , Schmidt Börge , Toth Peter P. , Rana Jamal S. , Lima Joao A. C. , Doria de Vasconcellos Henrique , Lloyd‐Jones Donald , Joshi Parag H. , Ayers Colby , Khera Amit , Blaha Michael J. , Greenland Philip , Nasir Khurram
Published: August 2022

Background

The value of coronary artery calcium (CAC) in the allocation of PCSK9i (proprotein convertase subtilisin/kexin type 9 inhibitors) among individuals without clinically evident atherosclerotic cardiovascular disease (ASCVD) is unknown for indications that do not require confirmed familial hypercholesterolemia. We aimed to assess the ability of CAC to stratify ASCVD risk under 3 non–familial hypercholesterolemia PCSK9i allocation paradigms.

Methods and Results

We included participants without clinically evident ASCVD from MESA (Multi‐Ethnic Study of Atherosclerosis), CARDIA (Coronary Artery Risk Development in Young Adults) study, DHS (Dallas Heart Study), and HNR (Heinz Nixdorf Recall) study. Three PCSK9i eligibility scenarios were defined: a broad scenario informed only by high low‐density lipoprotein cholesterol levels (N=567), a restrictive one combining higher low‐density lipoprotein cholesterol levels and presence of ≥2 additional risk factors (N=127), and a high‐risk scenario where individuals with subclinical organ damage or high estimated risk would be treated to achieve low‐density lipoprotein cholesterol <55 mg/dL (N=471). The high‐risk scenario had the highest ASCVD event rates (27.8% at 10 years). CAC=0 was observed in 35% participants in the broad scenario, 25% in the restrictive scenario, and 16% in the high‐risk scenario. In all, CAC=0 was associated with the lowest incident ASCVD rates at 5 and 10 years, and CAC burden was independently associated with ASCVD events adjusting for traditional risk factors.

Conclusions

CAC may be used to refine the allocation of PCSK9i, potentially leading to a more conservative use if CAC=0. The value of CAC testing is greater in scenarios that use low‐density lipoprotein cholesterol levels and/or traditional risk factors to define PCSK9i eligibility (CAC=0 present in 1 of 3–4 patients), whereas its prevalence is lower when allocation is informed by presence of noncoronary subclinical organ damage.
Risk of Stroke After Posterior Reversible Encephalopathy Syndrome
Authors: Parauda Sarah C. , Zhang Cenai , Salehi Omran Setareh , Schweitzer Andrew D. , Murthy Santosh B. , Merkler Alexander E. , Navi Babak B. , Iadecola Costantino , Kamel Hooman , Parikh Neal S.
Published: August 2022

Background:

Posterior reversible encephalopathy syndrome (PRES) can cause short-term cerebrovascular complications, such as brain infarction and hemorrhage. We hypothesized that PRES is also associated with an increased long-term risk of stroke.

Methods:

We performed a retrospective cohort study in the United States using statewide all-payer claims data from 2016 to 2018 on all admissions to nonfederal hospitals in 11 states. Adults with PRES were compared with adults with renal colic (negative control) and transient ischemic attack (TIA; positive control). Any stroke and the secondary outcomes of ischemic and hemorrhagic stroke were ascertained using
International Classification of Diseases, Tenth Revision, Clinical Modification codes
. We excluded prevalent stroke. We used time-to-event statistics to calculate incidence rates and Cox proportional hazards analyses to evaluate the association between PRES and stroke, adjusting for demographics and stroke risk factors. In a sensitivity analysis, outcomes within 2 weeks of index admission were excluded.

Results:

We identified 1606 patients with PRES, 1192 with renal colic, and 38 216 with TIA. Patients with PRES had a mean age of 56±17 years; 72% were women. Over a median follow-up of 0.9 years, the stroke incidence per 100 person-years was 6.1 (95% CI, 5.0–7.4) after PRES, 1.0 (95% CI, 0.62–1.8) after renal colic, and 9.7 (95% CI, 9.4–10.0) after TIA. After statistical adjustment for patient characteristics and risk factors, patients with PRES had an elevated risk of stroke compared with renal colic (hazard ratio [HR], 2.3 [95% CI, 1.7–3.0]), but lower risk than patients with TIA (HR, 0.67 [95% CI, 0.54–0.82]). In secondary analyses, compared with TIA, PRES was associated with hemorrhagic stroke (HR, 2.0 [95% CI, 1.4–2.9]). PRES was associated with ischemic stroke when compared with renal colic (HR, 1.9 [95% CI, 1.4–2.7]) but not when compared with TIA (HR, 0.49 [95% CI, 0.38–0.63]). Results were similar with 2-week washout.

Conclusions:

Patients with PRES had an elevated risk of incident stroke.
Strategic Substitution: China's Search for Coercive Leverage in the Information Age
Authors: Cunningham Fiona S.
Published: August 2022

China's approach to gaining coercive leverage in the limited wars that it has planned to fight against nuclear-armed adversaries differs from the choices of other states. A theory of strategic substitution explains why China relied on threats to use information-age weapons strategically instead of nuclear threats or conventional victories in the post–Cold War era. Information-age weapons (counterspace weapons, large-scale cyberattacks, and precision conventional missiles) promise to provide quick and credible coercive leverage if they are configured to threaten escalation of a conventional conflict using a “brinkmanship” or “calibrated escalation” force posture. China pursued information-age weapons when it faced a leverage deficit, defined as a situation in which a state's capabilities are ill-suited for the type of war and adversary that it is most likely to fight. China's search for coercive leverage to address those defi- cits became a search for substitutes because its leaders doubted the credibility of nuclear threats and were unable to quickly redress a disadvantage in the conventional military balance of power. A review of original Chinese-language written sources and expert interviews shows that China pursued a coercive cyberattack capability to address a leverage deficit after the United States bombed China's embassy in Belgrade in 1999. China's low dependence on information networks shaped its initial choice of a brinkmanship posture for large-scale offensive cyber operations. China switched to a calibrated escalation posture in 2014, following a dramatic increase in its vulnerability to cyberattacks.
Narratives and War: Explaining the Length and End of U.S. Military Operations in Afghanistan
Authors: Walldorf C. William
Published: August 2022

Why did the U.S. war in Afghanistan last so long, and why did it end? In contrast to conventional arguments about partisanship, geopolitics, and elite pressures, a new theory of war duration suggests that strategic narratives best answer these questions. The severity and frequency of attacks by al-Qaeda and the Islamic State across most of the 2000s and 2010s generated and sustained a robust collective narrative across the United States focused on combatting terrorism abroad. Audience costs of inaction generated by this narrative pushed President Barack Obama (2009) and President Donald Trump (2017) to not only sustain but increase troops in Afghanistan, against their better judgement. Strategic narratives also explain the end to the war. The defeat of the ISIS caliphate and a significant reduction in the number of attacks on liberal democratic states in the late 2010s caused the severity and frequency of traumatic events to fall below the threshold necessary to sustain a robust anti-terrorism narrative. As the narrative weakened, advocates for war in Afghanistan lost political salience, while those pressing retrenchment gained leverage over policy. Audience costs for inaction declined and President Joe Biden ended the war (2021). As President Biden seeks to rebalance U.S. commitments for an era of new strategic challenges, an active offshore counterterrorism program will be necessary to maintain this balance.
Competition between Associations in Memory
Authors: Caplan Jeremy B. , Hennies Nora , Sommer Tobias
Published: August 2022

If two associations share an item, one may be remembered at the expense of the other (BC recalled but not AB). Here, we identify the neural processes by which this competition materializes and is resolved. We analyzed fMRI signal while participants studied sets of pairs that reliably induced pair-to-pair associative interference, but which participants could not fully resolve. Precuneus activity tracked retrieval of previous pairs during study of later overlapping pairs. This retrieval apparently produced interference by diverting study resources from the currently displayed pair. However, when activity in ventromedial prefrontal cortex, as well as anterior subregions of the hippocampus, was present while the earlier pair had been studied, interference was reversed, and both pairs were likely to be recalled. Angular gyrus and mid-frontal activity were related to interference resolution once the participant had seen both pairs. Taken together, associations compete via precuneus-mediated competitive retrieval, but ventromedial prefrontal cortex may neutralize this by ensuring that when the earlier association is remembered while studying the later pair, memories of the two pairs can overcome interference likely via activity in mid-frontal cortex and angular gyrus.
An annotated checklist of the vascular flora of Quiçama National Park, Angola
Authors: MONTEIRO FRANCISCA , DA COSTA ESPERANÇA , KISSANGA RAQUEL , COSTA JOSÉ CARLOS , CATARINO LUÍS
Published: August 2022

The Quiçama National Park (PNQ), located in Luanda Province, Angola, is one of the oldest protected areas in the country. Although some work has been done on the flora of the Park, up to now a comprehensive record of the vascular plant species has been lacking. The objective of the present study was to produce an inventory of the vascular plant diversity of PNQ, as well as to record the types of vegetation in which each species occurs, their habits, uses by local communities, common names, and conservation status. A total of 452 species were recorded, from 285 genera and 85 families. Two species are Pteridophytes, 99 are Monocotyledons, and 351 are Dicotyledons. The two largest families of the PNQ flora are the Fabaceae and the Poaceae. The Park hosts 14 species endemic to Angola, and one of them is restricted to this protected area. Of the 128 species with data on conservation status, 109 are considered of least concern, 13 are vulnerable, and six are endangered. Regarding useful plants, 237 species from 67 families were recorded. Of these, 196 are Dicotyledons and 41 are Monocotyledons. Most of them are used for medicinal purposes, the manufacturing of artefacts, and as sources of food.
Interannual Variability of Tropospheric Moisture and Temperature and Relationships to ENSO Using COSMIC-1 GNSS-RO Retrievals
Authors: Johnston Benjamin R. , Randel William J. , Braun John J.
Published: August 2022

Interannual variability of tropospheric moisture and temperature are key aspects of Earth’s climate. In this study, monthly mean specific humidity (q) and temperature (T) variability is analyzed using 12 years of COSMIC-1 (C1) radio occultation retrievals between 60°N and 60°S, with a focus on the tropics. C1 retrievals are relatively independent of the a priori values for q and T within the lower/middle troposphere and upper troposphere/lower stratosphere, respectively. Tropical interannual variability is dominated by El Niño–Southern Oscillation (ENSO). Systematic increases and decreases in zonal mean q and T are observed during the 2009/10 and 2015/16 El Niño events and 2007/08 and 2010/11 La Niña events, respectively. ENSO patterns in q and T are isolated using linear regression, and anomaly magnitudes increase with altitude, reaching a maximum in the upper troposphere. Upper-tropospheric q anomalies expand from the tropics into the midlatitude lower stratosphere, and the T vertical structure is consistent with a moist adiabatic response. C1 results are compared with NCAR’s Whole Atmosphere Community Climate Model (WACCM), forced by observed sea surface temperatures, to evaluate model behavior in an idealized setting. WACCM ENSO variations in q and T generally show consistent behavior with C1 with somewhat smaller magnitudes. Case studies are conducted for major ENSO events during the study period. The spatial variability of q is closely aligned with outgoing longwave radiation (OLR) anomalies. For example, midtropospheric q increases over 100% and OLR decreases over 50 W m−2 over the central Pacific during the 2015/16 El Niño, and substantial regional q and T anomalies are observed throughout the tropics and midlatitudes for each event.
Quantifying and Understanding Forced Changes to Unforced Modes of Atmospheric Circulation Variability over the North Pacific in a Coupled Model Large Ensemble
Authors: O’Brien John P. , Deser Clara
Published: August 2022

While much attention has been given to understanding how anthropogenic radiative forcing influences the mean state of the climate system, far less scrutiny has been paid to how it may modulate naturally occurring modes of variability. This study investigates forced changes to unforced modes of wintertime atmospheric circulation variability and associated impacts on precipitation over the North Pacific and adjacent regions based on the 40-member Community Earth System Model version 1 Large Ensemble across the 1920–2100 period. Each simulation is subject to the same radiative forcing protocol but starts from a slightly different initial condition, leading to different sequences of internal variability. Evolving forced changes in the amplitude and spatial character of the leading internal modes of 500-hPa geopotential height variability are determined by applying empirical orthogonal function analysis across the ensemble dimension at each time step. The results show that the leading modes of internal variability intensify and expand their region of influence in response to anthropogenic forcing, with concomitant impacts on precipitation. Linkages between the Pacific and Atlantic sectors, and between the tropics and extratropics, are also enhanced in the future. These projected changes are driven partly by teleconnections from amplified ENSO activity and partly by dynamical processes intrinsic to the extratropical atmosphere. The marked influence of anthropogenic forcing on the characteristics of internal extratropical atmospheric circulation variability presents fundamental societal challenges to future water resource planning, flood control, and drought mitigation.
Satellite Estimates of Mode-1 M2 Internal Tides Using Nonrepeat Altimetry Missions
Authors: Zhao Zhongxiang
Published: August 2022

Previous satellite estimates of internal tides are usually based on 25 years of sea surface height (SSH) data from 1993 to 2017 measured by exact-repeat (ER) altimetry missions. In this study, new satellite estimates of internal tides are based on 8 years of SSH data from 2011 to 2018 measured mainly by nonrepeat (NR) altimetry missions. The two datasets are labeled ER25yr and NR8yr, respectively. NR8yr has advantages over ER25yr in observing internal tides because of its shorter time coverage and denser ground tracks. Mode-1 M2 internal tides are mapped from both datasets following the same procedure that consists of two rounds of plane wave analysis with a spatial bandpass filter in between. The denser ground tracks of NR8yr make it possible to examine the impact of window size in the first-round plane wave analysis. Internal tides mapped using six different windows ranging from 40 to 160 km have almost the same results on global average, but smaller windows can better resolve isolated generation sources. The impact of time coverage is studied by comparing NR8yr160km and ER25yr160km, which are mapped using 160-km windows in the first-round plane wave analysis. They are evaluated using independent satellite altimetry data in 2020. NR8yr160km has larger model variance and can cause larger variance reduction, suggesting that NR8yr160km is a better model than ER25yr160km. Their global energies are 43.6 and 33.6 PJ, respectively, with a difference of 10 PJ. Their energy difference is a function of location.

Significance Statement

Our understanding of internal tides is mainly limited by the scarcity of field measurements with sufficient spatiotemporal resolution. Satellite altimetry offers a unique technique for observing and predicting internal tides on a global scale. Previous satellite observations of internal tides are mainly based on 25 years of data from exact-repeat altimetry missions. This paper demonstrates that internal tides can be mapped using 8 years of data made by nonrepeat altimetry missions. The new dataset has shorter time coverage and denser ground tracks; therefore, one can examine the impact of window size and time coverage on mapping internal tides from satellite altimetry. A comparison of models mapped from the two datasets sheds new light on the spatiotemporal variability of internal tides.
On the Changes in Convection-Allowing WRF Forecasts of MCS Evolution due to Decreases in Model Horizontal and Vertical Grid Spacing. Part I: Changes in Cold Pool Evolution
Authors: Squitieri Brian J. , Gallus William A.
Published: August 2022

The degree of improvement in convective representation in NWP with horizontal grid spacings finer than 3 km remains debatable. While some research suggests subkilometer horizontal grid spacing is needed to resolve details of convective structures, other studies have shown that decreasing grid spacing from 3–4 to 1–2 km offers little additional value for forecasts of deep convection. In addition, few studies exist to show how changes in vertical grid spacing impact thunderstorm forecasts, especially when horizontal grid spacing is simultaneously decreased. The present research investigates how warm-season central U.S. simulated MCS cold pools for 11 observed cases are impacted by decreasing horizontal grid spacing from 3 to 1 km, while increasing the vertical levels from 50 to 100 in WRF runs. The 3-km runs with 100 levels produced the deepest and most negatively buoyant cold pools compared to all other grid spacings since updrafts were more poorly resolved, resulting in a higher flux of rearward-advected frozen hydrometeors, whose melting processes were augmented by the finer vertical grid spacing, which better resolved the melting layer. However, the more predominant signal among all 11 cases was for more expansive cold pools in 1-km runs, where the stronger and more abundant updrafts focused along the MCS leading line supported a larger volume of concentrated rearward hydrometeor advection and resultant latent cooling at lower levels.
Expanding and Enhancing Streamflow Prediction Capability of the National Water Model Using Real-Time Low-Cost Stage Measurements
Authors: Seo Bong-Chul , Rojas Marcela , Quintero Felipe , Krajewski Witold F. , Kim Dong Ha
Published: August 2022

This study demonstrates an approach to expand and improve the current prediction capability of the National Water Model (NWM). The primary objective is to examine the potential benefit of real-time local stage measurements in streamflow prediction, particularly for local communities that do not benefit from the improved streamflow forecasts due to the current data assimilation (DA) scheme. The proposed approach incorporates real-time local stage measurements into the NWM streamflow DA procedure by using synthetic rating curves (SRC) developed based on an established open-channel flow model. For streamflow DA and its evaluation, we used 6-yr (2016–21) data collected from 140 U.S. Geological Survey (USGS) stations, where quality-assured rating curves are consistently maintained (verification stations), and 310 stage-only stations operated by the Iowa Flood Center and the USGS in Iowa. The evaluation result from NWM’s current DA configuration based on the USGS verification stations indicated that DA improves streamflow prediction skills significantly downstream from the station locations. This improvement tends to increase as the drainage scale becomes larger. The result from the new DA configuration including all stage-only sensors showed an expanded domain of improved predictions, compared to those from the open-loop simulation. This reveals that the real-time low-cost stage sensors are beneficial for streamflow prediction, particularly at small basins, while their utility appears to be limited at large drainage areas because of the inherent limitations of lidar-based channel geometry used for the SRC development. The framework presented in this study can be readily applied to include numerous stage-only stream gauges nationwide in the NWM modeling and forecasting procedures.
The Only Fag Around: Twinship Needs In Gay Childhood
Authors: Guzzardi Sam
Published: August 2022

A number of contemporary psychoanalytic writers have characterized gay childhood as a profoundly isolating experience. Within a developmentally informed self psychological framework, the loneliness of gay childhood is theorized here as a deficit in requisite twinship experience in early life. A detailed clinical example illustrates how these thwarted twinship needs may reemerge in the transference to the analyst, and how patients may escalate their acting out when the analyst misattunes to, or altogether misses, manifestations of twinship longings in the transference. A bridge between Freud’s theory of the repetition compulsion and Kohut’s theory of selfobject transferences suggests how specific moments of thwarted twinship needs may be repeated within the analytic relationship in an attempt to master the earlier experience. The experience of the analyst being pulled into the patient’s attempts at mastery is detailed. A broader theoretical trend is hypothesized whereby psychoanalytic theories may have a pull toward twinship between each other.
The Influence of Strategic Disclosure on Corporate Climate Performance Ratings
Authors: Callery Patrick J.
Published: August 2022

In response to demand from investors and other stakeholders, companies have increased voluntary disclosure of climate change-related policies and performance. Information intermediaries have correspondingly emerged to provide needed credibility and commensurability of climate disclosures. However, the provision of performance ratings and lax audit capabilities creates opportunities for firms to manipulate those ratings for impression management. This article explains how firms may attain an intermediary’s favorable assessment of climate performance using varied methods of strategic disclosure. Using data from a prominent climate intermediary (CDP, formerly the Carbon Disclosure Project), I find that strategic disclosure is widespread and effective in attaining higher ratings, particularly through disclosure of forward-looking factors, suggesting that ratings may not be an accurate indicator of a firm’s true underlying performance. This article contributes to commensuration and impression management literatures, offers guidance for mechanism design to improve the reliability of intermediated voluntary disclosure, and highlights important areas for future research.
The perception and interpretation of conflicting mnemonic narratives: Post-communist remembrance in East Germany and Poland
Authors: Fiedler Anke , Rawski Tomasz , Świrek Krzysztof , Traunspurger Julia
Published: August 2022

Every society is marked by memory gaps. Taking Poland and (East) Germany as examples, we use a social constructivist-poststructuralist approach and conduct focus groups and qualitative interviews to investigate how the communist past is remembered in private everyday discourse and its differentiation from the hegemonic public memory discourse. Both countries exhibit striking parallels in their everyday and hegemonic memory practices, but they differ in how the memory gap is interpreted: in Poland along class lines, in Germany according to quasi-ethnic lines. Thus, the study shows that private–public memory gaps may determine the societal (re)production of group-specific identities in mnemonic conflicts.
Pro-integration policies and the occupational expectations of immigrant youth
Authors: Chykina Volha
Published: August 2022

Europe is experiencing heightened public attention toward anti-immigration policy reforms and restrictions. Despite the potential importance of these policy changes, we do not know whether these policies influence how immigrant children perceive their futures in their host countries. Employing secondary data analysis of the Program for International Student Assessment and the Migrant Integration Policy Index data, I show that a decrease in policy support for immigrant integration is associated with a decrease in how good of a job immigrant children expect to have when they are adults. Since students’ occupational expectations influence their eventual status attainment, this article shows that a decrease in pro-integration policies has important implications for the integration of immigrants into their host countries and for their life trajectories.
Entry Points: Gaining Momentum in Early-Stage Cross-Boundary Collaborations
Authors: Martínez Orbegozo Eva Flavia , de Jong Jorrit , Bowles Hannah Riley , Edmondson Amy , Nahhal Anahide , Cox Lisa
Published: August 2022

To address complex social challenges, it is widely recognized that leaders from public, for-profit, and civic organizations should join forces. Yet, well-intended collaborators often struggle to achieve alignment and fail to gain traction in their joint efforts. This article proposes the concept of “entry points” as a key milestone in a collaboration's early stages. Using a unique set of rich, longitudinal data, we examine how ten cross-boundary teams with representation from ten city governments in North America and Europe searched for these entry points (i.e., opportunities for focused action to advance learning and progress towards their collective goals). Based on systematic coding, we propose factors that impeded or enabled the teams' abilities to find entry points in their collaborative work. The paper contributes to literatures on cross-boundary collaboration, problem-oriented governance, and paradoxes in organizational behavior, and it offers an analytic framework to help cross-boundary collaboration practitioners identify their entry points.
Access and Repayment of Institutional Agricultural Credit by Farmers in Tribal Areas of Odisha: Trends, Determinants and Policy Measures
Authors: Behera Alok Ranjan , Behera Minaketan
Published: August 2022

Agricultural credit is the most significant factor in the Indian agricultural sector. The paper discusses the access of institutional credit to agriculture, and helps understand the challenges faced by the tribal farmers to obtain agricultural credit, and the determinants of institutional agricultural credit at households’ (HHs) level in the backward region of Odi:sha. The study used primary data collected from 475 farm tribal HHs of Kalahandi, Bolangiri and Koraput (KBK) districts in Odisha. The study found that increasing agricultural credit is greater in indirect finance than direct finance; in the same manner, a greater amount of credit is disbursed for the short term than the long term. Collateral issues, less awareness due to less education among farmers, low density of financial institutions in village areas, lack of finance as per demand, diversifying the loans from productive purpose to consumption purpose, and non-repayment of loan due to crop loss are different constraints faced by the farmers in Odisha.
Lightweight polyester composites via nanoreinforced syntactic foams
Authors: DiLoreto Edward , Berman Arielle , Moon Robert J , Kalaitzidou Kyriaki
Published: August 2022

Syntactic foams and their reinforcement with cellulose nanocrystals (CNC) in a thermosetting polyester resin (PR) matrix were studied in order to provide a pathway for lightweight composites for automotive applications with enhanced performance including thermomechanical properties and water uptake. A novel method for coating hollow glass spheres (HGS) with CNC was developed. Various combinations of functionalized CNC and surface modified HGS were studied to determine interactions between the two materials. Surface analysis techniques indicated that CNC were successfully deposited onto the HGS surface and remained at the surface after compounding with PR. Dynamic mechanical analysis of composites samples indicated a 30% increase in high temperature storage modulus between CNC coated HGS samples and uncoated HGS samples. Shifts in tan(δ) peak intensity and beta-relaxation temperature also indicated an increase in interphase volume around CNC coated HGS as compared to uncoated HGS samples. Coating HGS with CNC reduced the maximum water adsorption by as much as 40% indicating the potential for this material system in high moisture environments.
Introducing the Military Intervention Project: A New Dataset on US Military Interventions, 1776–2019
Authors: Kushi Sidita , Toft Monica Duffy
Published: August 2022

While scholars have made many claims about US military interventions, they have not come to a consensus on main trends and consequences. This article introduces a new, comprehensive dataset of all US military interventions since the country’s founding, alongside over 200 variables that allow scholars to evaluate theoretical propositions on drivers and outcomes of intervention. It compares the new Military Intervention Project (MIP) dataset to the current leading dataset, the Militarized Interstate Disputes (MID). In sum, MIP doubles the universe of cases, integrates a range of military intervention definitions and sources, expands the timeline of analysis, and offers more transparency of sourcing through historically-documented case narratives of every US military intervention included in the dataset. According to MIP, the US has undertaken almost 400 military interventions since 1776, with half of these operations undertaken between 1950 and 2019. Over 25% of them have occurred in the post-Cold War period.
External support in armed conflicts: Introducing the UCDP external support dataset (ESD), 1975–2017
Authors: Meier Vanessa , Karlén Niklas , Pettersson Therése , Croicu Mihai
Published: August 2022

In this article, we present the most up-to-date, fine-grained, global dataset on external support in armed conflicts: the UCDP External Support Dataset (ESD). The dataset encompasses data on states and non-state actors as both supporters and recipients and provides detailed information on the type of support provided to warring parties in armed conflicts between 1975 and 2017. We use it to highlight three broader trends in the provision of external support: (1) a dramatic increase in the number of external supporters, (2) a larger share of pro-government interventions, and (3) the rise of direct military intervention as the predominant mode of external support. In conclusion, we identify several avenues worthy of future inquiry that could significantly improve our understanding of external support in armed conflicts.
Animal welfare assessment after severe traumatic brain injury in rats
Authors: Allioux Clélia , Achaintre Laëtitia , Cheataini Fatima , Balança Baptiste , Marinesco Stéphane
Published: August 2022

Severe traumatic brain injury (TBI) is a multifactorial injury process involving respiratory, cardiovascular and immune functions in addition to the brain. Thus, live animal models are needed to study the molecular, cellular and systemic mechanisms of TBI. The ethical use of laboratory animals requires that the benefits of approaches be carefully weighed against potential harm to animals. Welfare assessments adapted to severe TBI research are lacking. Here, we introduce a scoresheet to describe and monitor potential distress in animals, which includes general welfare (body weight, general appearance and spontaneous behaviour) and TBI-specific indices (respiratory function, pain, locomotor impairment, wound healing). Implementation of this scoresheet in Sprague–Dawley rats subjected to severe lateral fluid percussion TBI revealed a period of suffering limited to four days, followed by a recovery to normal welfare scores within 10–15 days, with females showing a worse impact than males. The scores indicate that animal suffering in this model is transitory compared with TBI consequences in humans. The scoresheet allows for the implementation of refinement measures including (1) analgesia during the initial period following TBI and (2) humane endpoints set (30% weight loss, score ≥90 and/or respiratory problems). This animal scoresheet tailored to TBI research provides a basis for further refinement of animal research paradigms aimed at understanding or treating the sequelae of severe TBI.
A meta-analysis on the effects of incarceration-based opioid substitution treatment
Authors: Boksán K. , Dechant M. , Weiss M. , Hellwig A. , Stemmler M.
Published: August 2022

Objective: Opioid substitution treatment (OST) is a common treatment for individuals who use opioids; however, empirical evidence on the effects of OST during incarceration is scarce. Our aim was to conduct a meta-analysis on the effects of incarceration-based OST on substance use, treatment engagement post-release and re-incarceration. Method: We searched for studies on individuals who were incarcerated and treated with OST, compared to a comparison group. Studies were only included if they reported data post-release. Results: N = 15 studies met the inclusion criteria. We found less opioid use, less other drug use, higher treatment engagement post-release and less re-incarceration among treated individuals compared to the comparison group. Moderator analyses showed some influence of length of follow-up period and study quality. Conclusions: Incarceration-based OST reduces drug use, re-incarceration and leads to higher treatment engagement after release. More research is needed on the effects of incarceration-based OST on secondary outcomes (e.g. health and social integration) and on factors that moderate these effects.
The mediating role of positive reappraisal and self-compassion on the relationship between mindfulness and posttraumatic growth in patients with cancer
Authors: Aliche Chinenye Joseph
Published: August 2022

The beneficial effect of mindfulness in promoting posttraumatic growth has been well established in research, but it remains unclear what psychological mechanisms mediate it. This study examined the mediating roles of positive reappraisal and self-compassion on the relationship between mindfulness and posttraumatic growth in patients with cancer. A random sample of 550 patients drawn from two medical health care institutions in southeast, Nigeria participated in this study. Results of mediation analysis showed that positive reappraisal and self-compassion independently mediated the relationship between mindfulness and posttraumatic growth. These findings underscore the usefulness of mindfulness-based therapies in promoting cognitive emotional processes such as positive reappraisal abilities and self-compassion, which are essential in facilitating posttraumatic growth in patients with cancer.
Long-Term Hearing Stability at Different Frequencies after Lower Intact Bridge Tympanomastoidectomy and Possible Theoretical Basis
Authors: Wang Kaishi , Xing Lu , Jia Gaogan , Lin Hailiang , Ni Yusu
Published: August 2022

Objective: We aimed to review the long-term hearing outcomes of intact bridge tympanomastoidectomy (IBM) to discuss hearing preservation and combine the theory of “modified miniature lung,” middle ear ventilation, and gas pressure balance theory to explore the possible reasons for long-term stable hearing. Study Design: We designed a collection of patients with chronic suppurative otitis media (CSOM) who underwent IBM and divided them into 2 groups to compare long-term and short-term hearing level. Setting: From April 2007 to July 2017, 102 patients received IBM for CSOM treatment in Eye & ENT Hospital of Fudan University. Methods: We divided the patients into 2 groups according to whether the follow-up period was longer than 6 months. We used the numerical value of the air-bone gap difference as an index to evaluate the degree of hearing recovery. Results: We found that 99/102 (97.1%) of the hearings were improved to more than 3 frequencies. There was no significant difference between long-term hearing level and short-term hearing level, which means IBM could get long-term hearing stability. Conclusion: Intact bridge tympanomastoidectomy could provide significant hearing recovery and long-term hearing stability.
Concealed incision for resection of classical preauricular fistula
Authors: Liu Chunmiao , Niu Chunsheng
Published: August 2022

Objective

To introduce a new method of preauricular fistula resection and discuss its clinical efficacy.

Methods

Clinical data of 40 patients with 40 classical preauricular fistulas in our hospital were collected. The patients comprised of 19 male and 21 female patients aged 3-60 years. The fistula and part of the related cartilage were completely removed by a concealed incision on the inner side of the auricular crus, and the opening of the fistula was retained. The postoperative efficacy was analyzed.

Results

The operation time ranged from 15 to 30 minutes (mean, 25 minutes), and the blood loss ranged from 4 to 8 mL (mean, 5 mL). After complete fistula resection, the wound was closed with interrupted sutures. Dressing changes started 2 days after surgery and performed once a day, and the wound sutures were removed 7 days after surgery. All patients were followed up for 6 to 12 months (mean, 8.7 months) after surgery. Except for one patient with mild wound pain after suture removal, no patients developed infection or recurrence.

Conclusion

Use of a concealed surgical incision for treatment of a classical preauricular fistula has good results. There is no obvious scar on the ear after surgery and the procedure does not affect the facial appearance. It not only completely removes the lesion but also meets the patient’s esthetic needs.
The Interplay of Personality Traits and Social Network Characteristics in the Subjective Well-Being of Older Adults
Authors: Litwin Howard , Levinsky Michal
Published: August 2022

Using data from the Survey of Health, Ageing and Retirement in Europe, we regressed three well-being measures (CASP, life satisfaction and Euro-D depressive symptoms) on indicators of personality and social network. Personality was indicated by the Big-Five personality traits, while social network was measured in terms of size, contact frequency and emotional closeness. The analysis also considered personality—network interactions, controlling for confounders. The sample was comprised of 35,145 adults, aged 50 and older, from 24 European countries and Israel. The results revealed that the personality traits explained more variance in the well-being outcomes than the social network characteristics did. However, the interactions showed that the social network characteristics, particularly size and mean emotional closeness, offset the effects of dysfunctional personality attributes on subjective well-being in late life. Hence, social network characteristics were shown to modify the potentially ill effects of personality on key well-being indicators.
Race-Conscious Public Health: A Critical Discourse Analysis of the Release the Pressure Campaign
Authors: Markovich Hayley T.
Published: August 2022

In 2020, the Release the Pressure Campaign, a joint public health campaign was started to address the high rates of heart disease, and particularly hypertension, experienced among Black women in the United States. Through a Critical Discourse Analysis of mass media contents related to the campaign, this study sought to answer how the campaign used race to re-center Black women's heart health. Three discourses were determined, focused on embodiment of racism, self-care and community care, and addressing ways Black women treat heart disease. The discourses indicate the campaign is culturally focused and theoretically set up for success as a race-conscious public health campaign that has been advocated for. Future research is also discussed.
Are They Still Aiming High? The Development of Educational Aspirations of Lower Secondary School Students With Immigrant Backgrounds in Germany
Authors: Becker Birgit , Gresch Cornelia , Zimmermann Thomas
Published: August 2022

Although research indicates that students with immigrant backgrounds often have higher educational aspirations than students without immigrant backgrounds at the same performance level, little is known about the longitudinal development of this difference in aspirations. This article analyzes how idealistic and realistic educational aspirations from Grade 5 until Grade 9 in Germany develop for students from various migrant groups, compared with those without immigrant backgrounds at the same school track and at the same level of school performance. Drawing on different theoretical assumptions, we examine to what extent students (increasingly) adapt their aspirations to their school performance toward the end of compulsory schooling. Our empirical analysis uses data from the first five waves (Grades 5–9; 2010/11–2014/15) of the National Educational Panel Study in Germany ( N = 5,542). Random-effects model results show a positive association between students’ school performance and their idealistic and realistic aspirations, and this association tends to increase over time. However, there is no uniform pattern in students’ aspiration trajectories. Some migrant groups (Poland, Southern Europe, former Union of Soviet Socialist Republics) have similar aspiration trajectories as students without immigrant backgrounds at the same performance level, while other groups (Turkey, Northern and Western Europe, and others) maintain higher idealistic aspirations. Controlling for school performance, only students of Turkish origin also maintain higher realistic aspirations until Grade 9. These findings allow us to better understand the conditions behind the educational disadvantages of some migrant groups and offer insights into how best to further mitigate inequalities in educational outcomes.