bluuebunny/crossref_metadata_2025 huggingface dataset:
Design of Fluorescent Probes for Bioorthogonal Labeling of Carbonylation in Live Cells
Authors: Erkan Hazel , Telci Dilek , Dilek Ozlem
Published: May 2020

With the rapid development of chemical biology, many diagnostic fluorophore-based tools were introduced to specific biomolecules by covalent binding. Bioorthogonal reactions have been widely utilized to manage challenges faced in clinical practice for early diagnosis and treatment of several tumor samples. Herein, we designed a small molecule fluorescent-based biosensor, 2Hydrazine-5nitrophenol (2Hzin5NP), which reacts with the carbonyl moiety of biomolecules through bioorthogonal reaction, therefore can be utilized for the detection of biomolecule carbonylation in various cancer cell lines. Our almost non-fluorescent chemical probe has a fast covalent binding with carbonyl moieties at neutral pH to form a stable fluorescent hydrazone product leading to a spectroscopic alteration in live cells. Microscopic and fluorometric analyses were used to distinguish the exogenous and endogenous ROS induced carbonylation profile in human dermal fibroblasts along with A498 primary site and ACHN metastatic site renal cell carcinoma (RRC) cell lines. Our results showed that carbonylation level that differs in response to exogenous and endogenous stress in healthy and cancer cells can be detected by the newly synthesized bioorthogonal fluorescent probe. Our results provide new insights into the development of novel bioorthogonal probes that can be utilized in site-specific carbonylation labeling to enhance new diagnostic approaches in cancer.
A metal–organic framework with in situ generated low-coordinate binuclear Cu(i) units as a highly effective catalyst for photodriven hydrogen production
Authors: Huang Ning-Yu , He Hai , Li Hao , Liao Pei-Qin , Chen Xiao-Ming
Published: May 2020

Here, we report a metal–organic framework featuring a binuclear copper unit, showing extraordinarily high catalytic activity (102.8 mmol g−1 h−1) for photodriven H2 generation, which is attributed to the synergistic effect between the two Cu ions.
Magnetic molecularly imprinted conducting polymer for determination of praziquantel enantiomers in milk
Authors: Nascimento Tienne Aparecida , Silva Camilla Fonseca , Oliveira Hanna Leijoto de , da Silva Ricky Cássio Santos , Nascimento Clebio Soares , Borges Keyller Bastos
Published: May 2020

A new selective adsorbent based on magnetic molecularly imprinted conducting polymer was firstly synthetized and applied to the magnetic solid phase extraction (MSPE) for the determination of PZQ enantiomers in milk samples.
Biocompatible alkyne arms containing Schiff base fluorescence indicator for dual detection of CdII and PbII at physiological pH and its application to live cell imaging
Authors: Jebastin Andrews S. G. , Benita Jeba Silviya S. , Jeyanthi Dharmaraj , Sathya Devi E. , Winfred Jebaraj J. , Balakrishnan Chithiraivel
Published: May 2020

An alkyne arms containing salen-type Schiff base ligand L acts as a dual sensor for CdII and PbII with well-separated excitation and emission wavelengths. The ligand L has been utilized in cell imaging studies for both metal ions.
Synthesis, structural characterization, physicochemical properties and transformations of dehydroevodiamine and its hydrochloride salts
Authors: Zhang Guoshun , Shang Xiaoqing , Han Wei , Zhang Lifeng , Ren Guolian , Zhang Shuqiu
Published: May 2020

Five kinds of dehydroevodiamine (DHED) related crystals were harvested and transformations among evodiamine (EVO), DHED, DHED·HCl·2H2O and rutaecarpine (RUT) were revealed.
Halogen bonded metal bis(dithiolene) 2D frameworks
Authors: Hachem Hadi , Jeannin Olivier , Fourmigué Marc , Barrière Frédéric , Lorcy Dominique
Published: May 2020

Short and directional I⋯S halogen bonding interactions in iodinated bis(dithiolene) complexes lead to the crystallization of 2D or 3D anionic frameworks.
Single-particle study: effects of oxygen plasma treatment on structural and spectral changes of anisotropic gold nanorods
Authors: Kim Geun Wan , Ha Ji Won
Published: May 2020

Increasing the oxygen plasma treatment time gradually broadened the LSPR linewidth of the single gold nanorods.
Selenotungstates incorporating organophosphonate ligands and metal ions: synthesis, characterization, magnetism and catalytic efficiency in the Knoevenagel condensation reaction
Authors: Kong Hui , He Peipei , Yang Zongfei , Xu Qiaofei , Wang Jiawei , Ban Ran , Ma Pengtao , Wang Jingping , Niu Jingyang
Published: May 2020

Three new sandwich-type selenotungstate anion structures and Co1 show superior catalytic performance in the Knoevenagel condensation of benzaldehyde and ethyl cyanoacetate under mild conditions.
Humidity-responsive molecular gate-opening mechanism for gas separation in ultraselective nanocellulose/IL hybrid membranes
Authors: Janakiram Saravanan , Ansaloni Luca , Jin Soo-Ah , Yu Xinyi , Dai Zhongde , Spontak Richard J. , Deng Liyuan
Published: May 2020

A class of “green” hybrid membranes composed of nanocellulose and an ionic liquid exhibits exceptional separation properties arising from a humidity-responsive size-exclusive “gate” that allows selective CO2 permeation.
Optical microresonator arrays of fluorescence-switchable diarylethenes with unreplicable spectral fingerprints
Authors: Okada Daichi , Lin Zhan-Hong , Huang Jer-Shing , Oki Osamu , Morimoto Masakazu , Liu Xuying , Minari Takeo , Ishii Satoshi , Nagao Tadaaki , Irie Masahiro , Yamamoto Yohei
Published: May 2020

Photochromic microresonator arrays with whispering gallery mode fingerprints are successfully prepared, which function as high-security optical authentication microdevices.
Gold(i)–silver(i)-calix[8]arene complexes, precursors of bimetallic alloyed Au–Ag nanoparticles
Authors: Clément Marie , Abdellah Ibrahim , Martini Cyril , Fossard Frédéric , Dragoe Diana , Remita Hynd , Huc Vincent , Lampre Isabelle
Published: May 2020

We report the synthesis of new bimetallic gold(i)–silver(i) calix[8]arene complexes and their radiolytic reduction leading to small Au–Ag alloyed nanoparticles.
Application of modifier-free gold nanoparticle colorimetric sensing for rapid screening and detection of vitamin B1
Authors: Duenchay Paweenar , Kaewjua Kantima , Chailapakul Orawon , Siangproh Weena
Published: May 2020

A simple and fast alternative colorimetric sensing platform for selective determination of vitamin B1 in urine samples was proposed.
Arylation of indoles using cyclohexanones dually-catalyzed by niobic acid and palladium-on-carbons
Authors: Ban Kazuho , Yamamoto Yuta , Sajiki Hironao , Sawama Yoshinari
Published: May 2020

3-Arylindoles could be effectively constructed from indoles and cyclohexanones in the presence of the dual catalysts of N2O5/C and Pd/C.
Dienaminodioate based multicomponent reactions with post-benzylic oxidative transformations mediated by DDQ
Authors: Ravindran Jaice , Yadhukrishnan Velickakathu O. , Asha Reghuvaran S. , Lankalapalli Ravi S.
Published: May 2020

Multicomponent reactions (MCRs) using dienaminodioate with post-benzylic oxidative transformation mediated by DDQ that afforded a diverse array of products are described.
Dual-site mixed layer-structured FAxCs3−xSb2I6Cl3 Pb-free metal halide perovskite solar cells
Authors: Choi Yong Kyu , Heo Jin Hyuck , Hong Ki-Ha , Im Sang Hyuk
Published: May 2020

Dual site mixing of FAxCs3−xSb2I6Cl3 forms stable 2D layer structure.
Novel lightweight open-cell polypropylene foams for filtering hazardous materials
Authors: Wu Fei , Huang Pengke , Luo Haibin , Wang Jin , Shen Bin , Ren Qian , He Pei , Zheng Hao , Zhang Liyang , Zheng Wenge
Published: May 2020

Lightweight polypropylene foams with similar geometries but different porous structures were prepared as filters for potentially hazardous materialsviasupercritical CO2extrusion foaming without the use of harmful reagents and the problems of floating micro-nano fibers.
A facile method for preparing Yb3+-doped perovskite nanocrystals with ultra-stable near-infrared light emission
Authors: Zhang Chunqian , Zhang Aidi , Liu Taoran , Zhou Lin , Zheng Jun , Zuo Yuhua , He Yongqi , Li Juhao
Published: May 2020

A facile method for fabricating CsPbBr3:Yb3+@SiO2 NCs which guarantees high PLQY and excellent stability at the same time.
Ultrathin δ-MnO2 nanoflakes with Na+ intercalation as a high-capacity cathode for aqueous zinc-ion batteries
Authors: Peng Haijun , Fan Huiqing , Yang Chenhui , Tian Yapeng , Wang Chao , Sui Jianan
Published: May 2020

Sodium-ion intercalated δ-MnO2 nanoflakes are applied in an aqueous rechargeable zinc battery cathode with high energy density and excellent durable stability.
Work function modification of PEDOT:PSS by mixing with barium acetylacetonate
Authors: Woon K. L. , Wong W. S. , Chanlek N. , Nakajima H. , Tunmee S. , Lee V. S. , Ariffin A. , Songsiriritthigul P.
Published: May 2020

Modification of poly(3,4-ethylenedioxythiophene)polystyrene sulfonate as electron injection layer.
Enhancing the performance of LARP-synthesized CsPbBr3 nanocrystal LEDs by employing a dual hole injection layer
Authors: Xu Dingyan , Wan Qun , Wu Siyao , Zhao Yu , Xu Xinglei , Li Liang , He Gufeng
Published: May 2020

The current and power efficiencies of CsPbBr3 NC LEDs are improved 1.5 and 1.8 times by employing a dual HAT-CN/MoO3 hole injection layer.
A novel series of phenolic temozolomide (TMZ) esters with 4 to 5-fold increased potency, compared to TMZ, against glioma cells irrespective of MGMT expression
Authors: Shervington Leroy , Ingham Oliver , Shervington Amal
Published: May 2020

The standard of care treatment for patients diagnosed with glioblastoma multiforme (GBM) is temozolomide (TMZ).
Position-locking of volatile reaction products by atmosphere and capping layers slows down photodecomposition of methylammonium lead triiodide perovskite
Authors: Zu Fengshuo , Schultz Thorsten , Wolff Christian M. , Shin Dongguen , Frohloff Lennart , Neher Dieter , Amsalem Patrick , Koch Norbert
Published: May 2020

Gas pressure and capping layers under ultrahigh vacuum prevent methylammonium lead triiodide photo-degradation due to efficient back-reaction of volatile compounds.
Vibrational characterization of a diiron bridging hydride complex – a model for hydrogen catalysis
Authors: Gee Leland B. , Pelmenschikov Vladimir , Wang Hongxin , Mishra Nakul , Liu Yu-Chiao , Yoda Yoshitaka , Tamasaku Kenji , Chiang Ming-Hsi , Cramer Stephen P.
Published: May 2020

Fe–H–Fe bridging iron hydrides in model systems and metalloenzymes: benefits and challenges in revealing their vibrational signatures using NRVS spectroscopy and DFT calculations.
A cathode interface engineering approach for the comprehensive study of indoor performance enhancement in organic photovoltaics
Authors: Torimtubun Alfonsina Abat Amelenan , Sánchez José G. , Pallarès Josep , Marsal Lluis F.
Published: May 2020

Organic photovoltaics (OPVs) have a promising future in reliable energy harvesting to drive low power consumption devices for indoor applications.
Flexible and transparent sensors for ultra-low NO2 detection at room temperature under visible light illumination
Authors: Wang Xiao-Xue , Li Hua-Yao , Guo Xin
Published: May 2020

Flexible and transparent sensors based on parallelly aligned In2O3 nanowires can detect ppb-level NO2 at room temperature under visible light (even under an iPhone screen). The sensing performances are maintained after bending and stability tests.
High performance potassium–sulfur batteries and their reaction mechanism
Authors: Zhao Xinxin , Hong Youran , Cheng Mingren , Wang Shiwen , Zheng Lei , Wang Jiangwei , Xu Yunhua
Published: May 2020

Free-standing microporous carbon fiber/small-molecule sulfur composite was fabricated and achieved excellent performance as a K-ion battery cathode. The material structure and reaction mechanism were systematically investigated.
A smart porous wood-supported flower-like NiS/Ni conjunction with vitrimer co-effect as a multifunctional material with reshaping, shape-memory, and self-healing properties for applications in high-performance supercapacitors, catalysts, and sensors
Authors: Xiong Chuanyin , Li Bingbing , Liu Heguang , Zhao Wei , Duan Chao , Wu Haiwei , Ni Yonghao
Published: May 2020

Wood-based materials are attracting extensive attention for applications in energy storage due to their environmental friendliness and the presence of numerous channels in their structure.
Intersystem crossing via charge recombination in a perylene–naphthalimide compact electron donor/acceptor dyad
Authors: Imran Muhammad , El-Zohry Ahmed M. , Matt Clemens , Taddei Maria , Doria Sandra , Bussotti Laura , Foggi Paolo , Zhao Jianzhang , Di Donato Mariangela , Mohammed Omar F. , Weber Stefan
Published: May 2020

Efficient triplet state production (singlet oxygen quantum yield: 80%) by SOCT-ISC was observed for a perylene–naphthalimide compact electron donor/acceptor dyad.
Recent advances in 0D nanostructure-functionalized low-dimensional nanomaterials for chemiresistive gas sensors
Authors: Yang Tingqiang , Liu Yueli , Wang Huide , Duo Yanhong , Zhang Bin , Ge Yanqi , Zhang Han , Chen Wen
Published: May 2020

0D functionalization on 1D or 2D backbones is highly effective to improve gas sensing performance due to synergistic effects.
Inducing planarity in redox-active conjugated polymers with solubilizing 3,6-dialkoxy-thieno[3,2-b]thiophenes (DOTTs) for redox and solid-state conductivity applications
Authors: Pittelli Sandra L. , Gregory Shawn A. , Ponder James F. , Yee Shannon K. , Reynolds John R.
Published: May 2020

A new family of redox-active dioxythienothiophene (DOTT) polymers are studied for their solid state ordering and doping susceptibility, along with their optical and electronic properties.
The role of cytochrome P450 gene rs1126742 polymorphism and risk of hypertension: a systematic review and meta-analysis
Authors: Huang Ziyin , Jiang Yufeng , Zhou Yafeng
Published: May 2020

Background: CYP4A11 gene T8590C (rs1126742) is proved to be an important locus that is relevant to hypertension. Various research on the relationship between rs1126742 polymorphism and hypertension have been published, but due to small sample sizes and limitations of the research objects, the combined results remain controversial.

Methods: We searched PubMed, Embase, OVID, Web of Science, Wan Fang, and CNKI databases for related articles. Three authors individually extracted data and the quality of studies was evaluated by using the 9-point Newcastle–Ottawa Scale (NOS) independently. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated in different genetic models by using a random-effect model or fixed-effect model according to inter-study heterogeneity. Besides, subgroup analysis and sensitivity analysis were performed and the publication bias was assessed.

Results: There were totally 12 independent case–control studies of 8673 cases and 6611 controls included. Significant associations were found between CYP4A11 gene T8590C polymorphism and hypertension under all genetic models (allele, homozygote, heterozygote, recessive, and dominant model). We also found that there was no obvious relationship between the rs1126742 polymorphism and hypertension in Asian. But positive association has been found in Caucasian in allele, homozygote, and recessive model.

Conclusions: CYP4A11 gene T8590C (rs1126742) polymorphism increases the occurrence of hypertension, particularly in Caucasian.
Programmes de sélection du bovin N’Dama en Afrique de l’Ouest : cas du Sénégal, du Mali et de la Gambie
Authors: Camara Younouss , Sissokho Mouhamadou Moustapha , Sall Moussa , Farnir Frédéric , Antoine-Moussiaux Nicolas
Published: May 2020

La sélection génétique est un moyen pour augmenter la productivité des races endémiques dans des environnements hostiles. La trypanotolérance du bovin N’Dama a été l’argument central de la mise en œuvre des programmes de sélection de cette race en Gambie, au Mali et au Sénégal. Ces programmes ont eu des trajectoires différentes selon les objectifs, le processus de conception et les stratégies développées. L’analyse de ces trajectoires aiderait à mieux comprendre leurs succès et leurs échecs. Pour ce faire, une étude comparative de ces programmes a été réalisée en se basant sur une littérature scientifique publiée et non publiée et des entretiens avec les acteurs. L’analyse a d’abord consisté à décrire chaque programme. Une discussion a ensuite été menée pour évaluer les facteurs de succès et d’échec. Cette analyse a montré que ces facteurs dépendent de l’intérêt des éleveurs en lien avec leurs objectifs de production et leurs pratiques, de la stratégie utilisée tenant compte de l’intégration ou non de la trypanotolérance dans les critères de sélection, et de la mobilisation des ressources financières et humaines. Ces programmes de sélection ont aussi généré un capital d’expériences, dont la valorisation permettrait d’améliorer les systèmes actuels et de bâtir des programmes durables de sélection pour les systèmes d’élevage à faibles niveaux d’intrants dans les pays en développement.
Blockchain application in mining management
Authors: Hristova Teodora
Published: May 2020

A new tool for achieving a sustainable business climate in mining is DLT communication and blockchain data recording. The introduction of DLT will help increase confidence among participants mining executives, employees, regulators and suppliers. The factors that interdict the implementation of DLT are classified. Each of them has been analyzed and models for data exchange among roles have been proposed for illustration. The example is for measurement of the energy consumed and the material mined for an open pit. A scheme for the introduction of correction in case of measurement unaccuracy has been developed.
Approach for preliminary determination of the type and number of vertical rods in grounding installations
Authors: Petrov Petar , Velev Georgi , Ivanov Krasimir
Published: May 2020

The paper inhere describes a new practical approach for fast preliminary onsite estimation of the number and the kind of vertical grounding rods as essential components of all grounding systems in electrical power facilities, networks and installations in industry, communal services, mining enterprises, etc.
Mine planning subject to prepared ore reserves rationing
Authors: Rysbekov Kanay , Toktarov Ayan , Kalybekov Tursyn , Moldabayev Serik , Yessezhulov Timur , Bakhmagambetova Gulnara
Published: May 2020

This article deals with production planning in the context of providing technology at each mining stage with developed and ready-tostoping reserves. In order to address the problem, the ore body is represented by a geological block model. Numerical data is used to represent the attributes of each block, such as mass, density, ore grade, rock type. The mining plan provision with reserve standards on the degree of reconnaissance for production is reduced to the optimization task solution. The main condition for ensuring the planned production productivity of the mine is to provide the minimum necessary developed reserves. In the proposed mathematical model, it is taken into account by one of the objective function’s terminators for solving the set task. As the results of the calculations have shown, such a scheduling ensures approach that there is developed ore’s sufficient amount for at least 6 months at the beginning of each period, which is a clear advantage of the proposed model.
Adsorption purification of waste water from chromium by ferrite manganese
Authors: Frolova Liliia , Kharytonov Mykola , Klimkina Iryna , Kovrov Oleksandr , Koveria Andrii
Published: May 2020

Plasma method is used to synthesize manganese ferrite. The basic properties of ferrite are determined by IR spectroscopy, UV spectroscopy, X-ray phase analysis, vibration magnetometry. The paper shows that the use of magnetically controlled sorbent allows to purify waste waters from chromium (III). The process of adsorption of chromium cations (III) is investigated. The kinetics of the process is studied. To describe the equilibrium isotherms, the experimental data are analysed by the models of Langmuir, Freundlich isotherms. Pseudo-first order, pseudo-second-order, and Weber-Morris are used to elucidate the kinetic parameters and mechanism of the adsorption process. It has been established that the removal of Cr (III) cations is described by the pseudo-second order of the Langmuir reaction and mechanism.
Evaluation of the creditworthiness of extractive industry companies
Authors: Pukala Ryszard , Vnukova Nataliya , Tokhtamysh Tetiana , Yaholnytskyi Oleksandr , Hranko Kateryna
Published: May 2020

The article uses the methodology of assessing the creditworthiness of the National Bank of Ukraine as a borrower for extractive industry companies taking into account the principles and recommendations of the Basel Committee on Banking Supervision. According to the financial statements of the extractive industry companies, variables and coefficients have been counted to calculate the objective function of the integral indicator. The classes of debtors of the surveyed enterprises by years are determined. It has been proved that, with average creditworthiness, the activity of extractive industry companies is risky, but these companies need to attract external funds and financial resources. To measure the risk level of the group of surveyed companies, we used the calculation of asymmetry parameters of the statistical distribution, which showed that the activity of extractive industry companies is risky due to the peculiarities of the industry.
Industrial property management: sectorial aspect
Authors: Stryzhak Olena , Akhmedova Olena , Sushchenko Olena , Pokolodna Mariia
Published: May 2020

The necessity to determine the theoretical foundations of the effective management system organization for the creation and implementation of high technologies into the economic activity of domestic enterprises has been substantiated in the paper. The study objective is to formulate the theoretical foundations for the organization of an effective industrial property management system in the economic sector. The comparative characteristics of the industrial property items by their names, the form of legal protection and the classification features defined by the current legislation of Ukraine has been provided. The use of Structured Analysis and Design Technique (SADT) has been proposed in the paper to ensure the organization of the industrial property management process. As a practical implementation of the mechanism of organizational support for the process of industrial property management in the economic sector, the authors of the article have developed a business model for the organization of industrial property management in the economic sector with an in-depth structuring of business processes. The systematization of the industrial property management functions within the developed business model will help to identify the ways to improve the process of creation and sale of industrial property items in the mining industry.
The role of microbiota in paleoecosystems for forming the molecular profile of coals
Authors: Balalaiev Oleksandr
Published: May 2020

Mass deposits of fossil coals can be formed in certain evolution periods of the Earth’s biosphere, and they are the result of biogeocenosis functioning. A unique combination of ecological factors leads to the emergence of specific biomes with short trophic chains, an imbalance in the carbon cycle and desynchronization in the flows of substance and energy. The molecular structure of coal is a complex conglomerate of various stable organic compounds of primary and secondary metabolites of biogeocenosis reducers. The molecular profile includes numerous classes of lowand high-molecular organic substances that interact closely with each other. Multiple classes are not endless, the interaction is not chaotic, and their number and relationships are determined by paleoecologic patterns and coalification. Even a small fragment of the profile includes valuable information about the genesis of individual compounds and the biogeochemical situation when forming the coal bed. Microbiota impact does not end with a period of mortmass accumulation, which is never fully mineralized. In the coalification process, favorable environmental conditions may arise for the rebirth of the microorganisms’ lives in coal beds.
Determination of the limiting angle of inclination of tubular belt conveyor
Authors: Kiriia Ruslan , Smirnov Andrii , Zhyhula Tetiana , Zhelyazov Todor
Published: May 2020

Currently, the widespread use of tubular belt conveyors is constrained by insufficient justification of the conveyor parameters. In the work, on the basis of the theory of the limiting equilibrium state of bulk load, equations of equilibrium of load on the belt of an inclined tubular conveyor are obtained. It is assumed that the belt was a rigid cylinder filled with bulk material in extreme equilibrium. Based on the obtained equilibrium equation, the analytical dependences of the limiting angle of inclination of the belt conveyor with a tubular belt on the degree of unfilling with the bulk load of the belt and the properties of the bulk load are found. From the analysis of these dependencies it follows that the limiting angle of inclination of the tubular belt conveyor depends on the angle of internal friction of the transported load, the angle of friction of the load on the conveyor belt, the angle of unfilling of the belt with load and does not depend on the radius of the conveyor belt.
Kinetics of scandium recovery by TVEX-TBP from the solution formed after the salt chlorinator cake leaching
Authors: Korovin Vadym , Pohorielov Yurii , Shestak Yurii , Valiaiev Oleksandr , Cortina Jose Luis
Published: May 2020

Kinetics of scandium recovery by TVEX containing tributyl phosphate was studied from the clarified leaching solution of salt chlorinator cake. To assess the contribution of each diffusion phase, experimental data were analyzed using a graphic method. To define the contribution of chemical interaction into the scandium extraction process, recovery kinetics was quantitatively described using pseudo-first order, pseudo-second order kinetic models and Elovich equation in linearized form. It was established that recovery kinetics was most accurately described with the pseudo-second-order model.
The choice of mining development strategy based on the improved Bayes criterion
Authors: Lapshin Yevhen , Blyuss Borys , Dziuba Serhii , Tatarko Larysa
Published: May 2020

The choice of mining development strategies is based on the main indicators of mining and geological conditions that characterize mineral deposits. The purpose of the research is to argue the application of the improved Bayes criterion when choosing rational mining development strategies by taking into account the complex mining and geological conditions. The methodology of decision-making in terms of managing geotechnical systems depends on whether or not the probabilities of the conditions and dynamics of the parameters of rocks and soils are known during the development of mineral deposits, as well as the construction of infrastructure facilities. If the probabilities are unknown, then there is the problem of making decisions in the conditions of uncertainty of the initial data to assess the efficiency of the mining enterprises. And if the probabilities are known, then we are dealing with the task of making decisions in conditions of risk and assess the safety of mining operations. The improvement of the Bayes criterion enables us to determine, with an acceptable range of changes in efficiency, a strategy which provides more likely an increase in economic efficiency compared to a strategy selected using the traditional Bayes criterion.
Numerical simulation of flow-induced acoustic oscillations around circular cylinders
Authors: Mirnyi Serhii , Polevoy Oleg , Zinchenko Andrii , Pylypenko Anton , Vlasenko Vasyl
Published: May 2020

Questions of numerical simulation of acoustic oscillations generation modes in the liquid flow around the groups of two and three circular cylinders are considered. In mining industry the processes of hydrodynamic impact on gas-saturated porous media produce significant acoustic emission both at the injection stage and at the liquid discharge stage. Simulation of such kind of acoustic processes is one of the actual problems of theoretical and applied fluid mechanics and under certain assumptions could be reduced to the flow around a group of bodies. Two approaches for numerical simulation of the acoustic oscillations generation induced by the flow around circular cylinders based on numerical solution of the Navier-Stokes equations for compressible and incompressible flows closed by differential model of turbulence and complemented by acoustic analogy equations have been developed. For laminar flows, eight different modes that fundamentally differ both in the flow structure and in the frequency spectrum of parameter oscillations have been identified. For turbulent flows, the classification criteria for the three main frequency modes are presented. Acoustic data are obtained using the Direct Noise Computation technology and acoustic analogies as well.
Influence of paleodislocation intensity and modern movements on the stressed state of massif
Authors: Pymonenko Dmytro
Published: May 2020

To study the nature of the forces determining the stress state of the massif, the results of experimental studies of determining numerical values and spatial orientation of the main components of the active stress field using the local hydraulic fracturing method in coal mines of Central Region of Donbas are compared with maps characterizing the intensity of the distribution of paleo-and modern tectonic processes in the area of Donbas. Statistical relationships between indicators characterizing the stress state and the physicomechanical properties of rock are established. The results of performed studies show that the stress fields measured under the conditions of the mines of the Central Region of Donbas are mainly due to modern movements, but the paleological disturbances of tectonic blocks with disjunctive dislocations have a significant effect on the change in the stress state of the massif.
Technological solutions for mining of off-balance gypsum reserves in difficult geological conditions
Authors: Skipochka Serhii , Serhiienko Viktor , Amelin Volodymyr , Sytnichenko Oleh , Faucher Thibault
Published: May 2020

Mining technological solutions for underground mining of offbalance gypsum reserves in difficult mining and geological conditions were justified. An analysis of typical geological disturbances of gypsum seams is carried out using the Artemivsk deposit (Ukraine) as an example. Physical and mechanical properties of rocks in disturbed zones are determined. A quantitative assessment of strength characteristics of rocks during their moistening is carried out. The minimum permissible values of the width of the tape pillar and the power of the protective stack above the camera in the presence of a violation in the roof are calculated. The use of selective mining of the lower part of the seam by combines of the “Roadheader” type is recommended. The maximum width and height of the chamber are determined by the type of combine. The technology has been tested and realized at the gypsum mine of the Additional Liability Company “Siniat”.
Designing and loaded tooth contact analysis of an Archimedean worm gear drive focusing for the connecting teeth of the worm wheel by loaded torques
Authors: Bodzás Sándor
Published: May 2020

The cylindrical worm gear drives are widely used in different mechanical construction such as in the vehicle industry, the robotics, the medical appliances etc. The main property of them is the perpendicular and space bypass axes arrangement. Quite high transmission ratio could be achieved because of the high number of teeth of the worm-wheel and a little number of threads of the worm. More teeth are connected on the worm-wheel at the same time that is why higher loads and power could be transferred. In this research an Archimedean type cylindrical worm gear drive was designed. After the determination of the geometric parameters the computer-aided models were created for the LTCA analysis. Knowing of the kinematic motions of the elements the contact points of the wrapping surfaces could be determined by mathematical way. The necessary coordinate system's arrangements and matrixes were also determined. Different torques were applied during the LTCA. The changing of the distribution of the normal stress and normal deformation into different directions was followed on each connecting tooth of the worm-wheel by the torques. Based on the results consequences were determined by the created diagrams which contain the torques and the analysed mechanical parameter for each tooth.
Effect of marine environment on the behaviour of concrete structures reinforced by composite materials
Authors: Djelal Chafika , Long Mardy , Haddi Abdelkader , Szulc Julien
Published: May 2020

This study deals with experimental investigations of beam performances in a marine environment. Two kinds of concrete beams, unreinforced and reinforced with carbon plates and carbon rods, are being tested. The first one is stored in a laboratory, the other is exposed to a marine environment located in the north of France. After 12 months, all beams are tested via a four-point bending test in a laboratory. Results obtained have shown that beams stored in marine environment have a better behaviour than those stored in laboratory. It should be noted that no damage has occurred on these beams. However, we observe a significant increase of load of about 32% to 48% causing the first crack observed on the beams stored in marine environment compared to those stored in the laboratory. This means that beams in situ offer increased stiffness and a slight gain of failure loads. This may be due to the development of living organisms (in a marine environment) which acted as additional adhesive and sealing, providing a protection of concrete structures against damage.
Mental models in nuclear emergency management
Authors: Zeleznik N. , Benighaus L. , Mitrakos D. , Tafili V. , Duranova T. , Sala R. , Benighaus C.
Published: May 2020

This paper reports on the research of mental models of uncertainties management in an emergency situation which was carried out in the framework of the European CONFIDENCE (COping with uNcertainties For Improved modelling and DEcision making in Nuclear emergenCiEs) Project. The methodology included the mapping of mental models among several emergency preparedness and response experts and then performing interviews based on structured protocol with lay people in five countries: Germany, Greece, Slovak Republic, Slovenia and Spain. The aim of these investigations was to trace the concepts and understandings of emergency preparedness and response and to identify possible gaps between experts and lay people. The article presents the main results of this research and suggestions for the improvement of EP & R planning.
Endoscopic management of gastrointestinal motility disorders – part 1: European Society of Gastrointestinal Endoscopy (ESGE) Guideline
Authors: Weusten Bas L. A. M. , Barret Maximilien , Bredenoord Albert J. , Familiari Pietro , Gonzalez Jan-Michel , van Hooft Jeanin E. , Ishaq Sauid , Lorenzo-Zúñiga Vicente , Louis Hubert , van Meer Suzanne , Neumann Helmut , Pohl Daniel , Prat Frederic , von Renteln Daniel , Savarino Edoardo , Sweis Rami , Tack Jan , Tutuian Radu , Martinek Jan
Published: May 2020

Main Recommendations

ESGE recommends the use of a graded pneumatic dilation protocol in achalasia, starting with a 30-mm dilation and followed by a 35-mm dilation at a planned interval of 2 – 4 weeks, with a subsequent 40-mm dilation when there is insufficient relief, over both a single balloon dilation procedure or the use of a larger balloon from the outset.

Strong recommendation, high quality of evidence, level of agreement 100 %.

ESGE recommends being cautious in treating spastic motility disorders other than achalasia with peroral endoscopic myotomy (POEM).

Strong recommendation, very low quality of evidence, level of agreement 87.5 %.

ESGE recommends against the routine use of botulinum toxin injections to treat patients with non-achalasia hypercontractile esophageal motility disorders (Jackhammer esophagus, distal esophageal spasm). However, if, in individual patients, endoscopic injection of botulinum toxin is chosen, ESGE recommends performing injections into four quadrants of the lower esophageal sphincter and in the lower third of the esophagus.

Strong recommendation, low quality of evidence, level of agreement 78.6 %.

ESGE recommends that endoscopic pylorus-directed therapy should be considered only in patients with symptoms suggestive of gastroparesis in combination with objective proof of delayed gastric emptying using a validated test, and only when medical therapy has failed.

Strong recommendation, very low quality of evidence, level of agreement 100 %.

ESGE recommends against the use of botulinum toxin injection in the treatment of unselected patients with gastroparesis.

Strong recommendation, high quality of evidence, level of agreement 92.9 %.

ESGE recommends consideration of gastric peroral endoscopic myotomy (G-POEM) in carefully selected patients only, because it is an emerging procedure with limited data on effectiveness, safety, and durability. G-POEM should be performed in expert centers only, preferably in the context of a clinical trial.

Strong recommendation, low quality of evidence, level of agreement 100 %.
Effect of resealing on microleakage of resin composite restorations in relationship to margin design and composite type
Authors: Antonson Sibel A , Yazici A. Ruya , Okte Zeynep , Villalta Patricia , Antonson Donald E , Hardigan Patrick C
Published: May 2020

Objective: To determine the relationship between margin preparation design and resin-composite type on microleakage with or without re-application of surface-penetrating sealant.

Methods: Class-I resin-composite restorations were completed for 128 extracted human molars. Half of the margins were beveled, the other half, butt-joint. Half of each group was restored with Filtek-Supreme (FS), the other half with Esthet-X (EX) using their respective adhesive systems. Margins were etched and sealed with a surface-penetrating sealant, Fortify. The samples were stored in water 24h, and thermocycled (5,000 cycles, 5°C-55°C). Then, samples were abraded using a toothbrush machine (6,000 strokes). Half of the restorations from each sealant group (n=16) were resealed, and the other half had no further treatment. Thermocycling and tooth brushing were repeated. The samples were sealed with nail polish, immersed in methylene-blue for 8h, sectioned, and magnified digital photographs were taken. Three examiners assessed dye penetration. A 2x2x2 multi-layered Chi-Square analysis, using Cochran-Mantel-Haenszel test was conducted for statistical analysis.

Results: No difference was observed between sealed and resealed FS and EX restorations with butt-joint margins. In beveled margins, resealing caused significantly less microleakage (P<.01). No differences were found between restorations either sealed or resealed with bevel margins. In butt-joint margins, at the leakage level deeper than 2/3 of the preparation depth, resealed FS showed less microleakage than EX resealed restorations (P<.01).

Conclusion: Resealing reduced microleakage in bevel margins, however, in butt-joint margins resealing did not affect the leakage. A significant statistical relationship exists between and within resealing, margin preparation design, type of composite, and microleakage. (Eur J Dent 2012;6:389-395)
Does an additional UV LED improve the degree of conversion and Knoop Hardness of light-shade composite resins?
Authors: Giorgi Maria Cecília Caldas , Aguiar Flávio Henrique Baggio , Soares Luís Luís , Martin Airton Abrahão , Liporoni Priscila Christiane Suzy , Paulillo Luís Alexandre Maffei Sartini
Published: May 2020

Objective: The purpose of this study was to evaluate the degree of conversion (DC) using FTRaman spectroscopy and the Knoop hardness (KHN) of composites cured by second and third-generation LED light curing-units (LCU), Radii Cal and Ultralume 5.

Methods: Three composites (Filtek Supreme XT, Filtek Z350, and Esthet X) were selected for this study. KHN testing (n=10) was performed with 10 indentations for the top (T) and bottom (B) surfaces. For DC (n=10), both the T and B surfaces were analyzed.

Results: For KHN, the three composites differed in hardens. There was a “LCU-surface” interaction, in which Radii Cal showed significantly greater hardens in the B surface. For DC, there was a “composite-surface-LCU” interaction. For the “composite” factor, there was no significant difference between the groups, except for Supreme XT-Radii Cal (T or B surfaces). For the “LCU” factor there was a significant difference for Supreme XT T surface, Ultralume 5 obtained a higher DC. For the Z350 T surface, a significant difference in the DC in which Radii Cal obtained better results. For the “surface” factor, all groups presented T surfaces with a higher DC than the B surfaces, the sole exceptions involved Esthet X-Radii Cal and Z350-Ultralume 5.

Conclusion: Knowledge regarding composite composition and the characteristics of LCUs are important for effective polymerization. (Eur J Dent 2012;6:396-401)
Caries risk profiles in 2- to 6-year-old Greek children using the Cariogram
Authors: Kavvadia Katerina , Agouropoulos Andreas , Gizani Sotiria , Papagiannouli Lisa , Twetman Svante
Published: May 2020

Objective: To assess the caries risk profiles in 2- to 6-year-old Greek children using a computerbased program and to evaluate the contribution of various risk factors.

Methods: The study group consisted of 814 preschool children. A questionnaire on family, demographic and socioeconomic factors, general health, oral hygiene and dietary behavior was completed by the parents. Children were examined for cavitated and white-spot lesions (WSL). Salivary mutans streptococci (MS) and buffer capacity were estimated. Caries risk profiles were assessed with Cariogram.

Results:Cavitated lesions were found in 30% of the children; WSL were found in 26% of those included. MS and low buffer capacity were detected in 28% and 26% of the children, respectively. The majority (70%) displayed neglected oral hygiene. Based on the questionnaires, 83% of the children had a cariogenic diet, and 17% did not use any form of fluoride. The Cariogram revealed that 26% of the children had high caries risk, while only 9% exhibited low caries risk. The most significant caries risk variables, determined by regression analysis (R2=0.88), were insufficient fluoride exposure (! =0.160) and the presence of WSL (!= 0.159).

Conclusions: One-fourth of the children were categorised as high caries risk. The presence of WSL and lack of fluoride exposure were the most significant caries risk determinants. (Eur J Dent 2012;6:415-421)
Apical root resorption caused by orthodontic forces: A brief review and a long-term observation
Authors: Topkara Ahu , Karaman Ali I , Kau Chung H
Published: May 2020

External apical root resorption (ARR) is a common iatrogenic consequence of orthodontic treatment. One of the aims of this article is to present a brief overview of the literature, including; diagnosis and etiology, with emphasis on orthodontic forces to facilitate an understand of the prevention or management of ARR in orthodontic patients. We also present a long-term follow-up observation of severe ARR, including the last obtained cone beam computed tomography (CBCT) records, to demonstrate the effect of orthodontic forces on ARR. (Eur J Dent 2012;6:445-453)
Dual In Situ Generation of Aliphatic Vinyl Ethers and Electron-Deficient ortho-Quinone Methides for Inverse-Electron-Demand [4+2] Cycloaddition: A Selective One-Pot Synthesis of 3-Alkylchromanes
Authors: Hoshino Yujiro , Honda Kiyoshi , Tanaka Kenta , Ueno Ko , Tanaka Yuta , Ohtsuka Naoya , Asada Yosuke , Kishimoto Mami , Sunaga Shuto
Published: May 2020

An inverse-electron-demand [4+2] cycloaddition of in situ generated aliphatic vinyl ethers and electron-deficient ortho-quinone methides (o-QMs) has been developed. The reaction of in situ generated aliphatic vinyl ethers with o-QMs afforded the corresponding 3-alkylchromanes with high stereo- and regioselectivities. The method provides a versatile access to functionalized 3-alkylchromanes and it constitutes a useful tool for the synthesis of biologically active chromanes.
Ocular Trauma: Trends and Considerations for Resident Education
Authors: Dryden Stephen C. , Jensen Jason D. , Fleming James C. , Fowler Brian T.
Published: May 2020

Objective Ocular trauma is a mendable cause of morbidity and preventable blindness. Our goal is to confirm the relationship between ocular trauma and seasonality, to establish an association between ocular trauma and temperature, and to discuss implications on resident education.

Methods Consults for the University of Tennessee Health Science Center Hamilton Eye Institute Ophthalmology residency (Memphis, TN) were recorded in the New Innovations database from 2006 to 2016 and analyzed retrospectively. International Classification of Diseases-9 diagnosis codes were used to identify all cases of ocular trauma. Temperature data were obtained from the National Oceanic and Atmospheric Association. The main outcome measures were the monthly, seasonal, annual, and temperature trends in ocular trauma in an emergency department setting, necessitating an ophthalmology consultation.

Results A total of 8,400 patients were screened by ophthalmology residents in Memphis, TN from 2006 to 2016, 3,540 carried a diagnosis of ocular trauma, out of which 2,290 were male (64.7%) with a mean age of 34.6 years and 1,250 were female (35.3%) with a mean age of 34.9 years. The most common diagnoses were orbital fracture (36.6%), eyelid laceration (20.2%), and nonpenetrating corneal/conjunctival injury (13.6%). Peak months were July (37.3 cases/year) and September (36.6 cases/year) with trauma more likely to occur in nonwinter months (p = 0.0069). Trauma was more likely to occur in the summer/fall seasons (p = 0.0014) corresponding to mean temperatures 82.8 and 64.6°F, respectively.

Conclusion Ocular trauma exhibits an annual and temperature cycle, peaking in the summer and fall months, and coinciding with the beginning of the academic year. Special attention should be taken in July to prepare residents for the proper management of ocular trauma to prevent blindness as traumatic cases are more likely to require surgical intervention.