bluuebunny/crossref_metadata_2025 huggingface dataset:
Synthesis of a Novel Rigid Semi-Alicyclic Dianhydride and Its Copolymerized Transparent Polyimide Films’ Properties
Authors: Wang Yao , Liu Xiangfu , Shen Jiulin , Zhao Jianqiao , Tu Guoli
Published: October 2022

A new series of colorless polyimides (CPIs) with outstanding thermal properties and mechanical properties were fabricated by the copolymerization of a novel dianhydride and 4,4′-(hexafluoroisopropylidene)diphthalic anhydride (6FDA) with 2,2′-bistrifluoromethyl benzidine (TFDB). The novel dianhydride, 10-oxo-9-phenyl-9-(trifluoromethyl)-9,10-dihydroanthracene-2,3,6,7-tetraacid dianhydride (3FPODA), possessed a rigid semi-alicyclic structure, –CF3 and phenyl side groups, and an active carbonyl group. Benefitting from the special structure of 3FPODA, the glass transition temperatures (Tg) of the new CPIs improved from 330 °C to 377 °C, the coefficient of thermal expansion (CTE) decreased from 46 ppm/K to 24 ppm/K, and the tensile strength (TS), tensile modulus (TM), and elongation at break (EB) increased from 84 MPa to 136 MPa, 3.2 GPa to 4.4 GPa, and 2.94% to 4.13% with the increasing amount of 3FPODA, respectively. Moreover, the active carbonyl group of the 3FPODA could enhance the CPI’s adhesive properties. These results render the new dianhydride 3FPODA an ideal candidate monomer for the fabrication of high-performance CPIs.
DNA-Immobilized Special Conformation Recognition of L-Penicillamine Using a Chiral Molecular Imprinting Technique
Authors: Zhang Lianming , Luo Kui , Gao Jingxia , Li Jianping
Published: October 2022

A new chiral molecularly imprinted polymer (MIP) sensor with dual recognition ability was developed for the highly selective separation of enantiomers with toxic side effects in drugs. The sensor contains double-stranded deoxyribonucleic acid (dsDNA) as the element that immobilizes the chiral molecular conformation: the dsDNA enables the imprinted cavities to match the three-dimensional structure and functional groups from the chiral molecule. By embedding the spatial orientation of dsDNA in MIPs, one can accurately capture and immobilize the molecular conformation, eliminating the influence of interfering analogues. Herein, L-penicillamine (L-Pen) was selected as the chiral template molecule and embedded into dsDNA to form dsDNA-L-Pen complex, which was then embedded into the MIPs by electropolymerization. After elution, the stereo-selective imprinted cavities were obtained. The ATATATATATAT-TATATATATATA base sequence showed a high affinity for the embedded L-Pen, which endowed the imprinted cavities with a larger number of sites and improved the selectivity toward Pen enantiomers. Under the optimal working conditions, the current response of the MIP/dsDNA sensor exhibited a positive linear relationship with the logarithm of the L-Pen concentration in the range of 3.0 × 10−16 to 3.0 × 10−13 mol/L, and the detection limit was 2.48 × 10−16 mol/L. After the introduction of dsDNA into the MIP, the selectivity of the sensor toward D-Pen increased by 6.4 times, and the sensor was successfully applied in the analysis of L-Pen in penicillamine tablets.
The Mechanical Properties of Plant Fiber-Reinforced Geopolymers: A Review
Authors: Lv Chun , Liu Jie , Guo Guoliang , Zhang Yanming
Published: October 2022

Both geopolymer and plant fiber (PF) meet the requirements of sustainable development. Geopolymers have the advantages of simple preparation process, conservation and environmental protection, high early strength, wide source of raw materials, and low cost. They have broad application prospects and are considered as the most potential cementitious materials to replace cement. However, due to the ceramic-like shape and brittleness of geopolymers, their flexural strength and tensile strength are poor, and they are sensitive to microcracks. In order to solve the brittleness problem of geopolymers, the toughness of composites can be improved by adding fibers. Adding fibers to geopolymers can limit the growth of cracks and enhance the ductility, toughness and tensile strength of geopolymers. PF is a good natural polymer material, with the advantages of low density, high aspect ratio. It is not only cheap, easy to obtain, abundant sources, but also can be repeatedly processed and biodegradable. PF has high strength and low hardness, which can improve the toughness of composites. Nowadays, the research and engineering application of plant fiber-reinforced geopolymers (PFRGs) are more and more extensive. In this paper, the recent studies on mechanical properties of PFRGs were reviewed. The characteristics of plant fibers and the composition, structure and properties of geopolymers were reviewed. The compatibility of geopolymer material and plant fiber and the degradation of fiber in the substrate were analyzed. From the perspective of the effect of plant fibers on the compression, tensile and bending properties of geopolymer, the reinforcing mechanism of plant fibers on geopolymer was analyzed. Meanwhile, the effect of PF pretreatment on the mechanical properties of the PFRGs was analyzed. Through the comprehensive analysis of PFFRGs, the limitations and recommendations of PFFRG are put forward.
Synthesis and Characterization of Polymers Containing Ethynylene and Ethynylene-Thiophene Based Alternating Polymers Containing 2,1,3-Linked Naphthothiadiazole Units as Acceptor Linked with Fluorine as Donor: Electrochemical and Spectroscopic Studies
Authors: Al-Azzawi Ahmed G. S. , Dannoun Elham M. A. , Aziz Shujahadeen B. , Iraqi Ahmed , Al-Saeedi Sameerah I. , Nofal Muaffaq M. , Murad Ary R.
Published: October 2022

The effect of ethynylene or ethynylene–thiophene spacers on the band gap of alternating polymers, containing 4,9-naphthothiadiazole units as an acceptor and 2,7-linked fluorene repeat units as a donor, were investigated. The Sonogashira coupling reaction was employed to prepare the two novel copolymers, namely ((9,9-dioctyl-fluorene)-2,7-diethynylene-alt-4,9-2,1,3-naphthothiadiazole (PFDENT) and poly(5,5’-(9,9-dioctyl-fluorene-2,7-diyl)bis(ethynyl-2-thienyl)-alt-4,9-(2,1,3-naphthothiadiazole) (PFDTENT). The optical, electrochemical and thermal properties of the two obtained polymers were widely investigated and compared. Both resulting polymers showed low solubility in common organic solvents and moderate molecular weights. It is believed that the introduction of acetylene linkers rather than acetylene–thiophene spacers on the polymer chains reduces the steric hindrance between the donor and acceptor units which leads to the adoption of more planar structures of polymeric chains, resulting in decreased molecular weights of the resulting conjugated polymers. Thus, both ethynylene-based polymers and ethynylene–thiophene-based polymers showed red-shifted absorption maxima compared to their counterpart (thiophene-based polymer), owing to the adoption of more planar structures. Optical studies revealed that the new ethynylene and ethynylene–thiophene-based polymers displayed low band gaps compared to their thiophene analogue polymer PFDTNT. Both resulting polymers showed good thermal stability. X-ray diffraction (XRD) patterns of both polymers revealed that PFDENT and PFDTENT possessed an amorphous nature in solid state.
Hydrophobicity and Biodegradability of Silane-Treated Nanocellulose in Biopolymer for High-Grade Packaging Applications
Authors: Surya Indra , Hazwan C. M. , Abdul Khalil H. P. S. , Yahya Esam Bashir , Suriani A. B. , Danish Mohammed , Mohamed Azmi
Published: October 2022

The growing concern about pollution produced by plastic waste and the consequent environmental dangers has led to increased interest in replacing plastics with sustainable and biodegradable alternatives. Biopolymers such as seaweed have been examined for their film-forming characteristics to make edible films for packaging applications. This study aimed to prepare biopolymeric packaging films through a solvent-casting process using natural red seaweed (Kappaphycus alvarezii) and kenaf cellulose nanofiber (CNF), followed by film surface treatment using silane. The hydrophobic properties of the seaweed/CNF biopolymer were examined through water solubility (WS), moisture absorption capacity (MAC), water vapor permeability (WVP), and contact angle (CA) measurements. Fourier transform infra-red (FT-IR) film spectra clearly showed successful modification of the seaweed film (SF) by silane and the incorporation of kenaf CNF over the surface of the seaweed film. The wettability-related analysis showed positive results in determining the modified film’s hydrophobicity properties. Film degradation analysis using the soil burial method showed a lower degradation rate for films with a higher CNF loading. Overall, the characterization results of the seaweed/CNF biopolymer film predicted hydrophobicity properties. The slow degradation rate was improved with surface modification using silane treatment and the incorporation of kenaf CNF filler with the seaweed matrix. As a result, we found that the seaweed/CNF biopolymer film could be used as high-grade packaging material in many potential applications.
Rheological Behaviour of WMA-Modified Asphalt Binders with Crumb Rubber
Authors: Turbay Emilio , Martinez-Arguelles Gilberto , Navarro-Donado Tatiana , Sánchez-Cotte Edgar , Polo-Mendoza Rodrigo , Covilla-Valera Elvis
Published: October 2022

Crumb rubber (CR) is one of the materials most widely used in the road infrastructure industry due to its mechanical and environmental benefits as an asphalt binder modifier. Nonetheless, CR decreases the workability of mixes by increasing the viscosity of the binder, leading to an increase in the production temperatures of asphalt mixes. However, warm mix technologies can reduce the temperature demand associated with these processes. The preceding explains the growing interest in producing rubberised asphalt binders incorporating warm mix asphalt (WMA) additives. In this research, the mechanical and rheological properties of a 60/70 penetration grade asphalt binder modified with CR (at a dosage of 15, 18 and 21% by the wet process) and WMA chemical additives (Evotherm M1 and Iterlow T) were investigated. Laboratory tests included penetration, softening point, rotational viscosity, frequency sweep through dynamic shear rheometer (DSR), and multiple stress creep recovery (MSCR) tests. The results indicate that CR increases the stiffness of the asphalt binder, which is reflected in a lower penetration grade and improved softening point. It also improves its rutting resistance but decreases fatigue performance. Furthermore, it has been shown that under the conditions studied, the higher the CR content, the more elevated the degree of stiffness and performance of the asphalt binder. On the other hand, WMA technology decreases asphalt stiffness and performance at high temperatures.
A Honeycomb-like Ammonium-Ion Fiber Battery with High and Stable Performance for Wearable Energy Storage
Authors: Sun Jiangdong , Nie Wenqi , Xu Shuai , Gao Pengxiang , Sun Shuang , Zheng Xianhong , Hu Qiaole , Xu Zhenzhen
Published: October 2022

Aqueous ammonium-ion batteries have attracted intense interest lately as promising energy storage systems due to the price advantage and fast charge/discharge capability of ammonium-ion redox reactions. However, the research on the strength and energy storage characteristics of ammonium-ion fiber batteries is still limited. In this study, an ammonium-ion fiber battery with excellent mechanical strength, flexibility, high specific capacity, and long cycle-life has been developed with a robust honeycomb-like ammonium vanadate@carbon nanotube (NH4V4O10@CNT) cathode. The fiber electrode delivers a steady specific capacity of 241.06 mAh cm−3 at a current of 0.2 mA. Moreover, a fiber full cell consisting of an NH4V4O10@CNT cathode and a PANI@CNT anode exhibits a specific capacity of 7.27 mAh cm−3 at a current of 0.3 mA and retains a high capacity retention of 72.1% after 1000 cycles. Meanwhile, it shows good flexibility and superior electrochemical performance after 500 times bending or at different deformation states. This work offers a reference for long-cycle, flexible fibrous ammonium-ion batteries.
Recycling of Thermoset Materials and Thermoset-Based Composites: Challenge and Opportunity
Authors: Morici Elisabetta , Dintcheva Nadka Tz.
Published: October 2022

Thermoset materials and their composites are characterized by a long life cycle with their main applications in aircrafts, wind turbines and constructions as insulating materials. Considering the importance of recovery and valorization of these materials at their end-of-life, avoiding landfilling, the interest concerning their recycling grows continuously. The thermoset materials and their composites, to be successfully recovered and valorized, must degrade their three-dimensional structures and recover the mono-oligomers and/or fillers. The thermoset materials could successfully degrade through thermal treatment at different temperatures (for example, above 1000 °C for incineration, ca. 500 °C for oxidation/combustion of organic constituents, etc.), chemical degradation by catalyst, irradiation with or without the presence of water, alcohol, etc., and mechanical recycling, obtaining fine particles that are useful as filler and/or reinforcement additives. Among these recycling methods, this mini-review focuses on the formulation and recovery method of innovative thermoset with in-build recyclability, i.e., materials having chemical links that could be degraded on-demand or containing dynamic covalent bonds to have re-processable and/or recyclable thermoset. This issue could be considered the future perspective in developing novel thermoset materials. The aim of this review is to get an overview of the state of the art in thermoset recycling and of the most commonly used thermoset composites, recovering valuable reinforcing fibers. Additionally, in this work, we also report not only known recycling routes for thermoset and thermoset-based composites, but also new and novel formulating strategies for producing thermosets with built-in recyclability, i.e., containing chemical-triggered on-demand links. This mini-review is also a valuable guide for educational purposes for students and specialized technicians in polymer production and recycling.
Chemical Modification, Characterization, and Activity Changes of Land Plant Polysaccharides: A Review
Authors: Li Zhi-Wei , Du Zhu-Mei , Wang Ya-Wen , Feng Yu-Xi , Zhang Ran , Yan Xue-Bing
Published: October 2022

Plant polysaccharides are widely found in nature and have a variety of biological activities, including immunomodulatory, antioxidative, and antitumoral. Due to their low toxicity and easy absorption, they are widely used in the health food and pharmaceutical industries. However, low activity hinders the wide application. Chemical modification is an important method to improve plant polysaccharides’ physical and chemical properties. Through chemical modification, the antioxidant and immunomodulatory abilities of polysaccharides were significantly improved. Some polysaccharides with poor water solubility also significantly improved their water solubility after modification. Chemical modification of plant polysaccharides has become an important research direction. Research on the modification of plant polysaccharides is currently increasing, but a review of the various modification studies is absent. This paper reviews the research progress of chemical modification (sulfation, phosphorylation, acetylation, selenization, and carboxymethylation modification) of land plant polysaccharides (excluding marine plant polysaccharides and fungi plant polysaccharides) during the period of January 2012–June 2022, including the preparation, characterization, and biological activity of modified polysaccharides. This study will provide a basis for the deep application of land plant polysaccharides in food, nutraceuticals, and pharmaceuticals.
On the Crashworthiness Behaviour of Innovative Sandwich Shock Absorbers
Authors: Acanfora Valerio , Baldieri Ferdinando , Garofano Antonio , Fittipaldi Francesco , Riccio Aniello
Published: October 2022

Increasing the impact resistance properties of any transport vehicle is a real engineering challenge. This challenge is addressed in this paper by proposing a high-performing structural solution. Hence, the performance, in terms of improvement of the energy absorbing characteristics and the reduction of the peak accelerations, of highly efficient shock absorbers integrated in key locations of a minibus chassis have been assessed by means of numerical crash simulations. The high efficiency of the proposed damping system has been achieved by improving the current design and manufacturing process of the state-of-the-art shock absorbers. Indeed, the proposed passive safety system is composed of additive manufactured, hybrid polymer/composite (Polypropylene/Composite Fibres Reinforced Polymers—PP/CFRP) shock absorbers. The resulting hybrid component combines the high stiffness-to-mass and strength-to-mass ratios characteristic of the composites with the capability of the PP to dissipate energy by plastic deformation. Moreover, thanks to the Additive Manufacturing (AM) technique, low-mass and low-volume highly-efficient shock-absorbing sandwich structures can be designed and manufactured. The use of high-efficiency additively manufactured sandwich shock absorbers has been demonstrated as an effective way to improve the passive safety of passengers, achieving a reduction in the peak of the reaction force and energy absorbed in the safety cage of the chassis’ structure, respectively, up to up to 30 kN and 25%.
Shear Bond Strength and Mode of Failure of Polypropylene Fibers in Orthodontic Flash-Free Adhesive
Authors: Chaimaungchuen Kitiporn , Riddhabhaya Apiwat , Niyomtham Nattisa , Sirisoontorn Irin
Published: October 2022

The purpose of this research is to evaluate the effects of magnetostrictive and piezoelectric scalers on the shear bond strength (SBS), failure mode of the polypropylene fiber adhesive brackets, and the load of both scaler tips. The adhesive precoated (APC) Flash-Free brackets were placed on the buccal surfaces of sixty maxillary first premolars, which were divided into three equal groups of 20 specimens each, following the control group (no scaling), the magnetostrictive group, and the piezoelectric group. All specimens were measured for SBS value by using a universal testing machine at a crosshead speed of 0.75 mm/minute. The mode of failure was examined under a×10 magnification light microscope digital camera and scores for the adhesive remnant index (ARI) were recorded and measured load between the magnetostrictive and piezoelectric groups. For statistical analysis, ANOVA and multiple comparison, as well as unpaired t-test and chi-square tests, at the 0.05 significance level were used. The results showed that the average SBS value of the control group was greater than that of the magnetostrictive group and the piezoelectric group. However, the SBS was not significantly influenced by ultrasonic instruments (p > 0.05). The ARI score and load showed no significant differences among the groups (p > 0.05). In conclusion, the SBS of the APC Flash-Free bracket wasn’t affected by using ultrasonic instrumentation around the base of the bracket.
3D Polymer Architectures for the Identification of Optimal Dimensions for Cellular Growth of 3D Cellular Models
Authors: Maibohm Christian , Saldana-Lopez Alberto , Silvestre Oscar F. , Nieder Jana B.
Published: October 2022

Organ-on-chips and scaffolds for tissue engineering are vital assay tools for pre-clinical testing and prediction of human response to drugs and toxins, while providing an ethical sound replacement for animal testing. A success criterion for these models is the ability to have structural parameters for optimized performance. Here we show that two-photon polymerization fabrication can create 3D test platforms, where scaffold parameters can be directly analyzed by their effects on cell growth and movement. We design and fabricate a 3D grid structure, consisting of wall structures with niches of various dimensions for probing cell attachment and movement, while providing easy access for fluorescence imaging. The 3D structures are fabricated from bio-compatible polymer SZ2080 and subsequently seeded with A549 lung epithelia cells. The seeded structures are imaged with confocal microscopy, where spectral imaging with linear unmixing is used to separate auto-fluorescence scaffold contribution from the cell fluorescence. The volume of cellular material present in different sections of the structures is analyzed, to study the influence of structural parameters on cell distribution. Furthermore, time-lapse studies are performed to map the relation between scaffold parameters and cell movement. In the future, this kind of differentiated 3D growth platform, could be applied for optimized culture growth, cell differentiation, and advanced cell therapies.
Synthesis and Evaluation of a Silver Nanoparticle/Polyurethane Composite That Exhibits Antiviral Activity against SARS-CoV-2
Authors: Lam Wing T. , Babra Tahkur S. , Smith Julian H. D. , Bagley Mark C. , Spencer John , Wright Edward , Greenland Barnaby W.
Published: October 2022

In this proof-of-concept study, we aim to produce a polyurethane (PU)-based composite that can reduce the amount of viable SARS-CoV-2 virus in contact with the surface of the polymeric film without further interventions such as manual cleaning. Current protocols for maintaining the hygiene of commonly used touchpoints (door handles, light switches, shop counters) typically rely on repeated washing with antimicrobial products. Since the start of the SARS-CoV-2 pandemic, frequent and costly surface sanitization by workers has become standard procedure in many public areas. Therefore, materials that can be retrofitted to touchpoints, yet inhibit pathogen growth for extended time periods are an important target. Herein, we design and synthesise the PU using a one-pot synthetic procedure on a multigram scale from commercial starting materials. The PU forms a robust composite thin film when loaded with 10 wt% silver nanoparticles (AgNPs). The addition of AgNPs increases the ultimate tensile strength, modules of toughness and modulus of elasticity at the cost of a reduced elongation at break when compared to the pristine PU. Comparative biological testing was carried out by the addition of pseudotyped virus (PV) bearing the SARS-CoV-2 beta (B.1.351) VOC spike protein onto the film surfaces of either the pristine PU or the PU nanocomposite. After 24 h without further human intervention the nanocomposite reduced the amount of viable virus by 67% (p = 0.0012) compared to the pristine PU treated under the same conditions. The significance of this reduction in viable virus load caused by our nanocomposite is that PUs form the basis of many commercial paints and coatings. Therefore, we envisage that this work will provide the basis for further progress towards producing a retrofittable surface that can be applied to a wide variety of common touchpoints.
The Role of Electrochemical and Spectroelectrochemical Techniques in the Preparation and Characterization of Conjugated Polymers: From Polyaniline to Modern Organic Semiconductors
Authors: Ledwon Przemyslaw , Lapkowski Mieczyslaw
Published: October 2022

This review article presents different electrochemical and spectroelectrochemical techniques used to investigate conjugated polymers. The development of this research area is presented from an over 40-year perspective—the period of research carried out by Professor Mieczyslaw Lapkowski. Initial research involved polymers derived from simple aromatic compounds, such as polyaniline. Since then, scientific advances in the field of conductive polymers have led to the development of so-called organic electronics. Electrochemical and spectroelectrochemical methods have a great influence in the development of organic semiconductors. Their potential for explaining many phenomena is discussed and the most relevant examples are provided.
The Effect of Multiple Applications of Phosphate-Containing Primer on Shear Bond Strength between Zirconia and Resin Composite
Authors: Klaisiri Awiruth , Maneenacarith Apichai , Jirathawornkul Nicha , Suthamprajak Panattha , Sriamporn Tool , Thamrongananskul Niyom
Published: October 2022

Occasional chipping can still occur with zirconia material despite its high strength. Emergency repairs can be accomplished using zirconia primer, adhesive agent, and resin composite when the fracture of zirconia exposes the zirconia framework. Phosphate-containing primers play an important role in zirconia surface treatment. The objective of this investigation was to evaluate the effect of multiple applications of phosphate-containing primer on shear bond strength between zirconia and resin composite. In this case, 78 zirconia discs were sandblasted by alumina particles; the zirconia was then randomized into six groups for single application and multiple applications of phosphate-containing primer according follows; group 1: no application, group 2: one application, group 3: two applications, group 4: three applications, group 5: four applications, and group 6: five applications. Adhesive was applied on the zirconia surface and the resin composite was bonded. Shear bond strength was assessed using a universal testing machine. The de-bonded surface was examined using a stereomicroscope. The shear bond strengths were statistically analyzed with one-way ANOVA and Bonferroni. Group 1 had the lowest shear bond strength with a significant difference compared to groups 2–6, whereas group 4 had the highest shear bond strength, with no significant difference compared to groups 5–6. The failure mode revealed 100% adhesive failure in all groups. In conclusion, to maximize shear bond strength at zirconia and resin composite interfaces, sandblasted zirconia surfaces should be treated with three applications of phosphate-containing primer prior to the adhesive agent.
Study on Mechanical Properties and High-Speed Impact Resistance of Carbon Nanofibers/Polyurethane Composites Modified by Polydopamine
Authors: Qi Feng , Gao Jun , Wu Bolun , Yang Hongyan , Qi Fugang , Zhao Nie , Zhang Biao , Ouyang Xiaoping
Published: October 2022

Polyurethane elastomers (PUE), with superior mechanical properties and excellent corrosion resistance, are applied widely to the protective capability of structures under low-speed impact. However, they are prone to instantaneous phase transition, irreversible deformation and rupture even arising from holes under high-speed impact. In this paper, mussel adhesion proteins were applied to modify carbon nanofibers (CNFs) in a non-covalent way, and creatively mixed with PUE. This can improve the dispersity and interfacial compatibility of nanofillers in the PUE matrix. In addition, the homogeneous dispersion of modified nanofillers can serve as “reinforcing steel bars”. The nanofillers and PUE matrix can form “mud and brick” structures, which show superb mechanical properties and impact resistance. Specifically, the reinforcement of 1.0 wt.% modified fillers in PUE is 103.51%, 95.12% and 119.85% higher than the neat PUE in compression modulus, storage modulus and energy absorption capability, respectively. The results have great implications in the design of composite parts for aerospace and army vehicles under extreme circumstances.
Effect of Polyethylene Glycol and Activated Carbon Macroparticles on Thermal Conductivity of Paraffin Wax for Thermal Storage Applications
Authors: Myat Lwin Phone , Ahmad Muhammad Shakeel , Pulidindi Indra Neel , Algarni Hamed , Kumar Laveet , Kalam Abul , Wageh S. , Pandey Adarsh Kumar , Akbar Altaf , Selvaraj Jeyraj
Published: October 2022

Low thermal conductivity is the major obstacle for the wide range utilization of phase change materials (PCMs), especially organic PCMs, for most practical applications in thermal engineering. This study investigates the potential of enhancing the charging and discharging rates of organic PCM (RT44HC) by introducing polyethylene glycol (PEG) and activated carbon macroparticles (ACMPs). Different concentrations of PEG and ACMPs ranging from 0.3 wt% to 2 wt% were tested separately. The optimized concentrations found were used as dual reinforcements to attain the highest possible thermal conductivity. The specimens were tested for a complete charging–discharging cycle using an improvised thermal apparatus. Use of ACMP alone resulted in a minimal reduction in complete charging–discharging time due to the settlement of ACMPs at the bottom after 2–3 heating–cooling cycles. However, the addition of PEG with ACMPs exhibited a reduction in charging–discharging time due to the formation of a stable dispersion. PEG served as a stabilizing agent for ACMPs. The lowest charging–discharging time of 180 min was exhibited by specimens containing 1 wt% PEG and 0.5 wt% ACMPs which is 25% lower compared to bare PCM.
An Ab Initio Investigation on Relevant Oligomerization Reactions of Toluene Diisocyanate (TDI)
Authors: Thangaraj Ravikumar , Fiser Béla , Qiu Xuanbing , Li Chuanliang , Viskolcz Béla , Szőri Milán
Published: October 2022

2,4- and 2,6-isomers of toluene diisocyanates (2,4-TDI and 2,6-TDI) are important raw materials in the polyurethane industry. These reactive compounds associate even under ambient conditions to form oligomers, changing the physicochemical properties of the raw material. Kinetically and thermodynamically relevant dimerization reactions were selected based on G3MP2B3 calculations from all possible dimers of phenyl isocyanate using these isocyanates as proxies. As it turned out, only the formation of the diazetidine-2,4-dione ring (11-dimer, uretdione) resulted in a species having an exothermic enthalpy of formation (−30.4 kJ/mol at 298.15 K). The oxazetidin-2-one ring product (1-2-dimer) had a slightly endothermic standard enthalpy of formation (37.2 kJ/mol at 298.15 K). The mechanism of the relevant cyclodimerization reactions was investigated further for 2,4-TDI and 2,6-TDI species using G3MP2B3 and SMD solvent model for diazetidine as well as oxazetidin-2-one ring formation. The formation of the uretdione ring structures, from the 2,4-TDI dimer with both NCO groups in the meta position for each phenyl ring and one methyl group in the para and one in the meta position, had the lowest-lying transition state (Δ#E0 = 94.4 kJ/mol) in the gas phase. The one- and two-step mechanisms of the TDI cyclotrimerization were also studied based on the quasi-G3MP2B3 (qG3MP2B3) computational protocol. The one-step mechanism had an activation barrier as high as 149.0 kJ/mol, while the relative energies in the two-step mechanism were significantly lower for both transition states in the gas phase (94.7 and 60.5 kJ/mol) and in ODCB (87.0 and 54.0 kJ/mol).
Vardenafil-Loaded Bilosomal Mucoadhesive Sponge for Buccal Delivery: Optimization, Characterization, and In Vivo Evaluation
Authors: Aldawsari Mohammed F. , Khafagy El-Sayed , Alotaibi Hadil Faris , Abu Lila Amr Selim
Published: October 2022

Vardenafil (VDF) is a relatively new phosphodiesterase-5 inhibitor that has limited oral bioavailability (≈15%). The objective of this study was to develop bilosome-based mucoadhesive buccal sponge for augmenting the oral bioavailability of VDF. VDF-loaded bilosomes were fabricated and optimized using a Box-Behnken design. The optimized VDF-loaded bilosomal formulation was assessed for surface morphology, particle size, thermal characteristics, and in vitro release. Afterwards, the optimized bilosomal formulation was incorporated into a cellulose-based matrix to obtain buccal sponge, which was evaluated for ex vivo permeation studies, in vivo oral bioavailability, and in vivo serum concentration of cyclic guanosine monophosphate (cGMP). The mean particle size and entrapment efficiency (%) of optimized bilosome formulation were 282.6 ± 9.5 nm and 82.95 ± 3.5%, respectively. In vitro release studies at pH 6.8 emphasized the potential of optimized bilosomal formulation to sustain VDF release for 12 h. Ex vivo permeation study using sheep buccal mucosa indicated significant enhancement in penetration of VDF from bilosomal buccal sponge compared to plain VDF gel. Pharmacokinetic study in Albino rats showed ~5 fold increase in relative bioavailability with bilosomal buccal sponge, compared to VDF suspension. In addition, VDF-loaded bilosomal buccal sponge triggered higher serum levels of cGMP, a biomarker of VDF in vivo efficacy, compared to oral VDF suspension. To sum up, bilosomes might represent a potential nanocarrier for buccal delivery of VDF, enhancing its oral bioavailability and therapeutic efficacy.
4th Generation Biomaterials Based on PVDF-Hydroxyapatite Composites Produced by Electrospinning: Processing and Characterization
Authors: dos Santos Gabriel Grube , Malherbi Milena Schroeder , de Souza Natália Silva , César Gabriel Batista , Tominaga Tania Toyomi , Miyahara Ricardo Yoshimitsu , de Mendonça Patrícia de Souza Bonfim , Faria Daniela Renata , Rosso Jaciele Márcia , Freitas Valdirlei Fernandes , Weinand Wilson Ricardo , Dias Gustavo Sanguino , Santos Ivair Aparecido , Cotica Luiz Fernando , Bonadio Taiana Gabriela Moretti
Published: October 2022

Biomaterials that effectively act in biological systems, as in treatment and healing of damaged or lost tissues, must be able to mimic the properties of the body’s natural tissues in its various aspects (chemical, physical, mechanical and surface). These characteristics influence cell adhesion and proliferation and are crucial for the success of the treatment for which a biomaterial will be required. In this context, the electrospinning process has gained prominence in obtaining fibers of micro- and nanometric sizes from polymeric solutions aiming to produce scaffolds for tissue engineering. In this manuscript, poly(vinylidene fluoride) (PVDF) was used as a polymeric matrix for the manufacture of piezoelectric scaffolds, exploring the formation of the β-PVDF piezoelectric phase. Micro- and nanometric hydroxyapatite (HA) particles were incorporated as a dispersed phase in this matrix, aiming to produce multifunctional composite membranes also with bioactive properties. The results show that it is possible to produce membranes containing micro- and nanofibers of the composite by the electrospinning process. The HA particles show good dispersion in the polymer matrix and predominance of β-PVDF phase. Also, the composite showed apatite growth on its surface after 21 days of immersion in simulated body fluid (SBF). Tests performed on human fibroblasts culture revealed that the electrospun membranes have low cytotoxicity attesting that the composite shows great potential to be used in biomedical applications as bone substitutions and wound healing.
Effect of Carbonyl Iron Particle Types on the Structure and Performance of Magnetorheological Elastomers: A Frequency and Strain Dependent Study
Authors: Salem Ayman M. H. , Ali Abdelrahman , Ramli Rahizar Bin , Muthalif Asan G. A. , Julai Sabariah
Published: October 2022

Magnetorheological elastomers (MREs) are smart viscoelastic materials in which their physical properties can be altered when subjected to a varying magnetic field strength. MREs consist of an elastomeric matrix mixed with magnetic particles, typically carbonyl iron particles (CIPs). The magnetic field-responsive property of MREs have led to their wide exposure in research. The potential development and commercialization of MRE-based devices requires extensive investigation to identify the essential factors that can affect their properties. For this reason, this research aims to investigate the impact of CIPs’ type, concentration and coating on the rheological and mechanical properties of MREs. Isotropic MREs are fabricated with four different CIP compositions differing between hard or soft, and coated or uncoated samples. Each MRE composition have three different concentrations, which is 5%, 10%, and 20% by volume. The dynamic properties of the fabricated samples are tested by compression oscillations on a dynamic mechanical analyzer (DMA). Frequency and strain dependent measurements are performed to obtain the storage and loss modulus under different excitation frequencies and strain amplitudes. The emphasis is on the magnetorheological (MR) effect and the Payne effect which are an intrinsic characteristics of MREs. The effect of the CIPs’ type, coating, and concentration on the MR and Payne effect of MREs are elucidated. Overall, it is observed that, the storage and loss modulus exhibit a strong dependence on both the frequency excitations and the strain amplitudes. Samples with hard and coated CIPs tend to have a higher MR effect than other samples. A decrease in the storage modulus and non-monotonous behavior of the loss modulus with increasing strain amplitude are observed, indicating the Payne effect. The results of this study can aid in the characterization of MREs and the proper selection of CIPs grades based on the application.
PHB Processability and Property Improvement with Linear-Chain Polyester Oligomers Used as Plasticizers
Authors: de Sousa Junior Rogerio Ramos , dos Santos Carlos Alberto Soares , Ito Nathalie Minako , Suqueira Airton Nizetti , Lackner Maximilian , dos Santos Demetrio Jackson
Published: October 2022

In 2021, global petroleum-based plastic production reached over 400 million metric tons (Mt), and the accumulation of these non-biodegradable plastics in the environment is a worldwide concern. Polyhydroxybutyrate (PHB) offers many advantages over traditional petroleum-based plastics, being biobased, completely biodegradable, and non-toxic. However, its production and use are still challenging due to its low deformation capacity and narrow processing window. In this work, two linear-chain polyester oligomers were used as plasticizers to improve the processability and properties of PHB. Thermal analyses, XRD, and polarized optical microscopy were performed to evaluate the plasticizing effect on the PHB and the reflection on the mechanical behavior. Both oligomers acted as PHB plasticizers, with a reduction in Tg and Tm as a function of the plasticizer concentration, which can make it easier to handle the material in thermal processing and reduce the probability of thermal degradation. Plasticizer 2 proved to be the most promising between the two with an optimized condition of 20%, in which there was a decrease in elastic modulus of up to 72% and an increase in the maximum elongation of 467%.
The Effect of Oxalic Acid as the Pre-Activator for the Electropolishing of Additive Manufactured Titanium-Based Materials and Its Characterization
Authors: Chen Chun-Hao , Lee Chia-Yu , Ger Ming-Der , Jian Shun-Yi , Hung Jung-Chou , Yang Po-Jen , Kao Chun-Hsiang , Ferng Yi-Cherng , Huang Ying-Sun , Jen Kuo-Kuang
Published: October 2022

The use of additive manufactured (AM) titanium-based materials has increased substantially for medical implants and aerospace components. However, the inferior surface roughness of additive manufactured products affects the outward appearance and reduces performance. This study determines whether activation treatment prior to electropolishing produces a better surface. Oxalic acid (OA) is used as a pre-activator using different experimental conditions and the surface roughness is reduced by electropolishing with an electrolyte of perchloric acid and glacial acetic acid. The SEM surface morphology, mechanical properties, phase transformation and electrochemical properties are measured to determine the effect of different degrees of roughness on the surface. The results show that the surface roughness of AM titanium-based samples decreases from 8.47 µm to 1.09 µm after activation using OA as a pre-treatment for electropolishing. After electropolishing using optimal parameters, the hardness and resistance to corrosion resistance are increased.
Molecularly Imprinted Ligand-Free Nanogels for Recognizing Bee Venom-Originated Phospholipase A2 Enzyme
Authors: Zaharia Anamaria , Gavrila Ana-Mihaela , Caras Iuliana , Trica Bogdan , Chiriac Anita-Laura , Gifu Catalina Ioana , Neblea Iulia Elena , Stoica Elena-Bianca , Dolana Sorin Viorel , Iordache Tanta-Verona
Published: October 2022

In this study, ligand-free nanogels (LFNGs) as potential antivenom mimics were developed with the aim of preventing hypersensitivity and other side effects following massive bee attacks. For this purpose, poly (ethylene glycol) diacrylate was chosen as a main synthetic biocompatible matrix to prepare the experimental LFNGs. The overall concept uses inverse mini-emulsion polymerization as the main route to deliver nanogel caps with complementary cavities for phospholipase A2 (PLA2) from bee venom, created artificially with the use of molecular imprinting (MI) technologies. The morphology and the hydrodynamic features of the nanogels were confirmed by transmission electron microscopy (TEM) and dynamic light scattering (DLS) analysis. The following rebinding experiments evidenced the specificity of molecularly imprinted LFNG for PLA2, with rebinding capacities up to 8-fold higher compared to the reference non-imprinted nanogel, while the in vitro binding assays of PLA2 from commercial bee venom indicated that such synthetic nanogels are able to recognize and retain the targeted PLA2 enzyme. The results were finally collaborated with in vitro cell-viability experiments and resulted in a strong belief that such LFNG may actually be used for future therapies against bee envenomation.
Effect of Epoxidized and Maleinized Corn Oil on Properties of Polylactic Acid (PLA) and Polyhydroxybutyrate (PHB) Blend
Authors: Sempere-Torregrosa Jaume , Ferri Jose Miguel , de la Rosa-Ramírez Harrison , Pavon Cristina , Samper Maria Dolores
Published: October 2022

The present work analyzes the influence of modified, epoxidized and maleinized corn oil as a plasticizing and/or compatibilizing agent in the PLA–PHB blend (75% PLA and 25% PHB wt.%). The chemical modification processes of corn oil were successfully carried out and different quantities were used, between 0 and 10% wt.%. The different blends obtained were characterized by thermal, mechanical, morphological, and disintegration tests under composting conditions. It was observed that to achieve the same plasticizing effect, less maleinized corn oil (MCO) is needed than epoxidized corn oil (ECO). Both oils improve the ductile properties of the PLA–PHB blend, such as elongation at break and impact absorb energy, however, the strength properties decrease. The ones that show the highest ductility values are those that contain 10% ECO and 5% MCO, improving the elongation of the break of the PLA–PHB blend by more than 400% and by more than 800% for the sample PLA.
Enhancement of Antimicrobial and Dyeing Properties of Cellulosic Fabrics via Chitosan Nanoparticles
Authors: Mosaad Rehab M. , Alhalafi Mona H. , Emam El-Amir M. , Ibrahim Marwan A. , Ibrahim Hassan
Published: October 2022

The primary goal of this study is to prepare chitosan nanoparticles (CSNPs) by the ionic gelation method via the treatment of chitosan (0.2 wt.%) with tripolyphosphate (0.2 wt.%) ultrasonically for 45 min. FT-IR spectroscopy and TEM images were used to characterize and validate CSNP production. Cellulosic materials with different concentrations of CSNPs have better antibacterial and colouring characteristics. The treated cellulosic fabrics were analyzed by FT-IR spectroscopy, SEM, and thermogravimetric analysis. Colourimetric data measurements expressed in K/S values were used to evaluate the impact of CSNPs on the dyeing affinity of cellulosic materials. In addition, antibacterial activity against bacteria and fungi was tested on the treated cellulosic fabrics. According to the K/S values, cellulosic textiles treated with CSNPs (0.3 wt.%) had a better affinity for acid dyeing. These textiles also offer better antibacterial properties and are more resistant to washing, light, and rubbing. A cytotoxicity study found that CSNPs give cellulosic materials antibacterial and acid dyeing properties, which is good for the environment.
Production of Thermoplastic Starch-Aloe vera Gel Film with High Tensile Strength and Improved Water Solubility
Authors: Abd Karim Siti Fatma , Idris Juferi , Jai Junaidah , Musa Mohibah , Ku Hamid Ku Halim
Published: October 2022

Biodegradable film packaging made from thermoplastic starch (TPS) has low mechanical performance and high water solubility, which is incomparable with synthetic films. In this work, Aloe vera (AV) gel and plasticized soluble potato starch were utilised to improve the mechanical stability and water solubility of TPS. Dried starch was mixed with glycerol and different AV gel concentrations (0% to 50%). The TPS + 50% AV gel (30 g TPS + 15 g AV gel) showed the best improvement compared to TPS alone. When compared to similar TPS films with AV gel added, this film is stronger and dissolves better in water. Mechanical qualities improved the tensile strength and Young’s modulus of the TPS film, with 1.03 MPa to 9.14 MPa and 51.92 MPa to 769.00 MPa, respectively. This was supported by the improvement of TPS water solubility from 57.44% to 46.6% and also by the increase in decomposition temperature of the TPS. This promises better heat resistance. The crystallinity percentage increase to 24.26% suggested that the formation of hydrogen bonding between TPS and AV gel enhanced crosslinking in the polymeric structure. By adding AV gel, the TPS polymeric structure is improved and can be used as a biodegradable food-packaging film.
Modelling and Simulation of MuCell®: The Effect of Key Processing Parameters on Cell Size and Weight Reduction
Authors: Ding Yifei , Vyas Cian , Bakker Otto , Hinduja Srichand , Bartolo Paulo
Published: October 2022

Microcellular injection moulding is an important injection moulding technique to create foaming plastic parts. However, there are no consistent conclusions on the impact of processing parameters on the cell morphology of microcellular injection moulded parts. This paper investigates the influence of the main processing parameters, such as melt temperature, mould temperature, injection pressure, flow rate, shot volume and gas dosage amount, on the average cell size and weight reduction of a talc-reinforced polypropylene square part (165 mm × 165 mm × 3.2 mm), using the commercial software Moldex 3D. The effect of each parameter is investigated considering a range of values and the simulation results were compared with published experimental results. The differences between numerical and experimental trends are discussed.
Enhanced Actuation Performance of Polymeric Composites by Simultaneously Incorporating Covalent-Bond-Functionalized Dielectric Nanoparticles and Polar Plasticizer
Authors: Lu Huiwan , Yang Dan
Published: October 2022

Dielectric elastomer actuators (DEAs), similar to artificial muscles, are widely applied in the fields of robotics and biomedical devices. In this work, 3-mercaptopropyl ethyoxyl di(tridecyl-pentaethoxy) silane (Si747)-modified BaTiO3 (BTO) nanoparticles (denoted as Si747@BTO) were utilized as dielectric filler to improve the dielectric constant while epoxy soybean oil (ESO) was employed as a plasticizer to decrease the elastic modulus, with the aim of improving the actuation performance of epoxy natural rubber (ENR) composites. The participation of Si747 in the vulcanization reaction of ENR led to the formation of covalent bonds between BTO and ENR chains, resulting in a uniform dispersion of BTO nanoparticles in the ENR matrix. Among obtained composites, the 50 phr ESO/Si747@BTO/ENR exhibited a relatively high actuated strain of 8.89% at 22 kV/mm, which is a value about 5.1-fold higher than that of pure ENR (1.45%) under the same electric field.