bluuebunny/crossref_metadata_2025 huggingface dataset:
An Isolated Cryptococcal Urinary Tract Infection in a Cat
Authors: Chapman Tara L. , Kirk Simon E.
Published: September 2014

A male domestic shorthaired cat was presented for evaluation of stranguria and pollakiuria. A cryptococcal urinary tract infection (UTI) was diagnosed cytologically and via fungal culture. No evidence of systemic involvement was found. Chronic renal failure was a concurrent disease in this cat. Treatment consisted of oral fluconazole. Clinical signs resolved after 2 weeks of therapy, and fluconazole was discontinued after 6 months when negative urine culture results indicated resolution of the infection. This case demonstrates that correct identification of cryptococcal UTI allows for administration of therapy that can be associated with resolution of clinical signs.
Progressive Myelopathy Due to a Spontaneous Intramedullary Hematoma in a Dog: Pre- and Postoperative Clinical and Magnetic Resonance Imaging Follow-up
Authors: Thibaud Jean-Laurent , Hidalgo Antoine , Benchekroun Ghita , Fanchon Laurent , Crespeau Francois , Delisle Francoise , Blot Stephane
Published: September 2014

A 4-year-old, male Jack Russell terrier was presented for a 6-month history of progressive right hemiparesis with episodic cervical hyperesthesia. The neurological examination showed a right-sided, upper motoneuron syndrome and partial Horner’s syndrome. Two magnetic resonance imaging (MRI) examinations were performed 3 months apart and revealed a persistent cervical intramedullary hematoma. A dorsal myelotomy was performed. A subacute hematoma was confirmed histologically without underlying lesions. Eighteen months later, the dog’s clinical signs were minimal. Two MRI examinations were performed 2 weeks and 5 months after surgery and revealed regressing signal abnormalities at the surgical site, consistent with a surgical scar.
Endobronchial Polyp Derived From a Myxosarcoma in the Lung of a Dog
Authors: Hill Richard C. , Ginn Pamela E. , Thompson Margret S. , Seguin M. Alexis , Miller Daphne , Taylor David P.
Published: September 2014

An endobronchial polyp was visible radiographically and bronchoscopically in an 11-year-old, mixed-breed dog with a persistent cough. The polyp was removed by traction. Initial histological examination suggested it was a myxomatous fibroma. The cough resolved but recurred with polyp regrowth. Two additional lung masses became visible radiographically. The polyp was removed twice more at 6-month intervals. Euthanasia was performed 15 months after first presentation when coughing recurred soon after the final bronchoscopy. Histological examination revealed that the mass was a myxomatous sarcoma. The lung contained two other unrelated tumors: a bronchioloalveolar carcinoma and a carcinoma of unknown origin.
Evaluations of Labrador Retrievers With Exercise-Induced Collapse, Including Response to a Standardized Strenuous Exercise Protocol
Authors: Taylor Susan M. , Shmon Cindy L. , Adams Vicki J. , Mickelson James R. , Patterson Edward (Ned) E. , Shelton G. Diane
Published: September 2014

Clinical and metabolic variables were evaluated in 14 Labrador retrievers with exerciseinduced collapse (EIC) before, during, and following completion of a standardized strenuous exercise protocol. Findings were compared with previously reported variables from 14 normal Labrador retrievers that participated in the same protocol. Ten of 14 dogs with EIC developed an abnormal gait during evaluation, and these dogs were significantly more tachycardic and had a more severe respiratory alkalosis after exercise compared to the normal dogs. Muscle biopsy characteristics and sequential lactate and pyruvate concentrations were normal. Genetic testing and linkage analysis excluded malignant hyperthermia as the cause of EIC. Common causes of exercise intolerance were eliminated, but the cause of collapse in EIC was not determined.
An Expedited Palliative Radiation Protocol for Lytic or Proliferative Lesions of Appendicular Bone in Dogs
Authors: Knapp-Hoch Heather M. , Fidel Janean Louise , Sellon Rance K. , Gavin Patrick R.
Published: September 2014

Fifty-eight dogs with lytic or proliferative bone lesions were treated with a radiation protocol of two 8-Gy fractions over 2 consecutive days. The protocol was well tolerated, with no increase in early or late effects over previously published protocols. Forty-three (91%) of 47 dogs responded positively to radiation, with a median time of 2 days to onset of pain relief. Median duration of pain relief was 67 days (range 12 to 503 days; mean 99±16 days). Median survival time for all dogs was 136 days (mean 179±18 days). Distal radial location was a positive prognostic indicator for survival (P=0.005).
Ectopic Hepatic Parenchyma Attached to the Diaphragm: Simulating a Pulmonary Mass in a Cat
Authors: Dhaliwal Ravinder S. , Lacey Janice K.
Published: September 2014

A case of an ectopic lobe of the liver connected to a normal diaphragm is described. A 9-year-old, castrated male cat underwent thoracotomy for a pulmonary mass. The removed mass was attached to the diaphragm that histologically was ectopic liver. The ectopic liver had no connection with the main liver. Because the occurrence of ectopic supradiaphragmatic hepatic tissue is a possibility, this should be considered as a differential diagnosis for caudal pulmonary or caudal mediastinal masses in a cat. This report describes, to the authors’ knowledge, the first case of ectopic hepatic tissue attached to the diaphragm of a cat. The authors also characterize the asymptomatic clinical presentation and radiographic findings of this cat and suggest further imaging with computed tomography in unusual case presentations.
Chylothorax Associated With Tricuspid Dysplasia and Atrial Septal Defect in a Bullmastiff
Authors: Diana Alessia , Guglielmini Carlo , Acocella Fabio , Valerio Flavio , Cipone Mario
Published: September 2014

Transudate pleural effusion associated with tricuspid dysplasia and ostium secundum-type atrial septal defect was diagnosed in a 14-month-old bullmastiff. Following administration of furosemide and an angiotensin-converting enzyme (ACE) inhibitor, the dog remained free of pleural effusion for 10 months, until he showed severe dyspnea due to chylothorax. Medical therapy was unsuccessful to avoid recurrence of life-threatening pleural chylous effusion. Ligation of the thoracic duct and apposition of an omental pedicle flap were effective in the resolution of pleural chylous leakage.
Enterocutaneous Fistula in a Dog Secondary to an Intraperitoneal Gauze Foreign Body
Authors: Frank Joseph D. , Stanley Bryden J.
Published: September 2014

A 6-year-old, spayed female German shepherd crossbreed had a 6-month history of a draining fistula in the left flank. Fistulography demonstrated an enterocutaneous fistula. Surgery revealed a granuloma that was enveloping the left ureter and caudal mesenteric artery and adhering to multiple loops of bowel. The granuloma centered on a gauze sponge inadvertently retained at time of ovariohysterectomy. Retained surgical foreign bodies can be avoided, and their frequency is likely underestimated. Risk factors identified in human medicine include emergency surgery, changes in surgical procedure, and obesity. A foreign body should be considered a potential cause of draining tracts in veterinary patients.
Extravesical Textiloma (Gossypiboma) Mimicking a Bladder Tumor in a Dog
Authors: Deschamps Jack-Yves , Roux Françoise A.
Published: September 2014

Sponges can be inadvertently left behind during surgery. A retained surgical sponge is called a textiloma, gossypiboma, or gauzoma. This complication is rare and rarely reported. These foreign bodies can lead to postoperative infection or abscess formation, while others remain asymptomatic for many years before leading to a granuloma with adhesions. This paper reports a case of extravesical textiloma in a spayed female dog with severe hematuria and a thickened bladder wall, mimicking a tumor on ultrasound. Clinical signs occurred >8 years after sterilization.
Metacarpophalangeal and Metatarsophalangeal Osteoarthritis in 49 Dogs
Authors: Franklin Samuel P. , Park Richard D. , Egger Erick L.
Published: September 2014

Although osteoarthritis (OA) is a common and debilitating condition in the canine patient, few data are available on OA of the metacarpophalangeal (MCP) and metatarsophalangeal (MTP) joints. Review of medical records of 49 dogs with a radiographic diagnosis of MCP or MTP OA presented over a 7-year period demonstrated that OA was an “incidental finding” for the majority of animals (n=35), while 14 dogs were identified as clinically lame as a result of MCP or MTP OA. Dogs that were clinically lame as a result of MCP or MTP OA were significantly more likely to have visible swelling over the affected digits. Five times as many dogs were diagnosed with MCP OA than with MTP OA, and the majority of dogs had radiographic changes on multiple digits. Review and scoring of radiographs (n=44 dogs) for six radiographic signs of OA followed by logistic regression analysis demonstrated that the two lateral digits of the front limb were significantly more likely to have osteophytosis and enthesophytosis than the two medial digits. Osteoarthritis of MCP and MTP joints has unique radiographic features that are not seen in the stifle, hip, shoulder, or elbow; these features can complicate accurate diagnosis, particularly differentiation from primary bone neoplasia. These data underscore the clinical relevance of this condition and provide useful information detailing which and how many digits are most commonly affected, potentially assisting discrimination between OA and neoplasia.
A Prospective Study of Unfractionated Heparin Therapy in Dogs With Primary Immune-Mediated Hemolytic Anemia
Authors: Breuhl Elizabeth L. , Moore George , Brooks Marjory B. , Scott-Moncrieff J. Catharine
Published: September 2014

Unfractionated heparin therapy was initiated at a standard dosage of 300 IU/kg subcutaneously q 6 hours to 18 dogs with immune-mediated hemolytic anemia. Heparin’s prolongation of activated partial thromboplastin time and change in factor Xa inhibition (anti-Xa activity) were serially monitored during the first 40 hours of therapy. During the initial 40 hours, only eight of 18 dogs had attained anti-Xa activities of ≥0.35 U/mL. No dogs had clinical signs of hemorrhage. Fifteen dogs survived to discharge; 11 dogs were alive at 1 year, and thrombosis was identified in three of six nonsurvivors that were necropsied.
Ectopic Thyroid Carcinoma Causing Right Ventricular Outflow Tract Obstruction in a Dog
Authors: Bracha Shay , Caron Isabelle , Holmberg David L. , O’Grady Michael R. , O’Sullivan Lynne M. , Brisson Brigitte A. , Stalker Margaret J.
Published: September 2014

A 9-year-old Bouvier des Flandres was presented with coughing, lethargy, chylous pleural effusion, and a heart murmur. An echocardiogram revealed the presence of an intracardiac mass causing right ventricular outflow tract obstruction. The mass was successfully removed surgically, using total inflow occlusion. Histopathology and immunohistochemistry identified the tumor as an ectopic thyroid carcinoma. The dog was euthanized 11 months after diagnosis at the request of the owner because of nonresolving chylothorax.
Primary Omental Abscessation or Omental Infarction in Four Dogs
Authors: Campbell Bonnie G.
Published: September 2014

Primary omental abscessation was diagnosed in three dogs after laparotomy. Laparotomy was performed to explore an abdominal mass of unknown origin and chronic fat necrosis diagnosed in one dog as an incidental finding during ovariohysterectomy. Primarily hypoechoic masses not connected to any abdominal structures were visualized with abdominal ultrasound in three dogs. Suppurative inflammation was diagnosed from fine-needle aspirate evaluation in two dogs. Bacteria were cultured from two abscesses despite the absence of organisms on Gram stain, cytology, and histopathology. Foreign material was found in one abscess. All four dogs experienced weight loss and/or an episode of gastrointestinal signs. Primary omental abscessation may be preceded by omental vascular compromise and/or interaction of the omentum with foreign material.
Mucinous Gastric Carcinoma With Abdominal Carcinomatosis and Hypergastrinemia in a Dog
Authors: de Brito Galvao Joao F. , Pressler Barrak M. , Freeman Lynetta J. , Rohleder Jacob J. , Burgess Richard C. F. , Ramos-Vara Jose A.
Published: September 2014

A 12-year-old, spayed female Australian cattle dog was evaluated for a 5-month history of progressive vomiting. Abdominal radiographs and ultrasound revealed significant gastric wall thickening and a peripancreatic mass, and serum gastrin concentration was increased (127 pg/mL, reference range 10 to 40 pg/mL). Surgical exploration of the abdomen revealed a thickened, firm, and irregular gastric fundus, pylorus, and antrum; nodules were present throughout the spleen and mesentery adjacent to the left limb of the pancreas. Mucinous gastric carcinoma with carcinomatosis was diagnosed by histopathological examination of surgically excised tissues. Unfortunately, severe postoperative complications resulted in euthanasia 10 days after surgery, and a necropsy was not performed. This case is significant, because it is the first report of a mucinous gastric carcinoma associated with hypergastrinemia in a dog.
Elevations in Sex Hormones in Dogs With Sudden Acquired Retinal Degeneration Syndrome (SARDS)
Authors: Carter Renee T. , Oliver Jack W. , Stepien Rebecca L. , Bentley Ellison
Published: September 2014

Dogs diagnosed with sudden acquired retinal degeneration syndrome (SARDS) commonly are presented with concurrent clinical, physical, and historical findings consistent with hyperadreno-corticism (HAC) at the time of vision loss. Thirteen dogs diagnosed with SARDS on the basis of complete ophthalmic examination and extinguished bright-flash electroretinogram were evaluated for steroid hormonal abnormalities. Signalment, case history, physical examination, and clinicopathological findings were recorded. Serum cortisol and sex-hormone concentrations were measured before and after adrenocorticotropic hormone (ACTH) stimulation. Clinical signs of HAC, systemic hypertension, and proteinuria were commonly found in dogs with SARDS. Elevations in one or more sex hormones were found in 11 (85%) of 13 dogs (95% confidence interval [CI] 65% to 100%); cortisol was elevated in nine (69%) of 13 dogs (95% CI 44% to 94%). A minority of dogs (three [23%] of 13; 95% CI 0.2% to 46%) exhibited only an increase in adrenal sex hormones. Only one dog had completely normal ACTH stimulation test results. Symptoms of HAC were associated with abnormal ACTH stimulation results. Routine ACTH stimulation testing to evaluate cortisol and sex hormones, blood pressure screening, and urinalysis are recommended in these animals.
Encephalitozoon cuniculi Infections in Dogs: A Case Series
Authors: Snowden Karen F. , Lewis Barbara C. , Hoffman Jay , Mansell Joanne
Published: September 2014

Encephalitozoon (E.) cuniculi has been occasionally identified as a cause of neurological or renal disease in dogs, but cases are not well documented in the United States. The medical records from a state veterinary diagnostic laboratory for 19 cases of fatal encephalitozoonosis in puppies were reviewed. Clinical histories included depression, inappetence, and progressive neurological signs of short duration. Histopathological evaluation showed brain and renal lesions typical of encephalitis and nephritis, respectively. Molecular analyses of parasites from 13 cases confirmed the identity of the organisms as E. cuniculi strain III. This parasite may be an underdiagnosed cause of fatal canine neurological or renal disease.
Patellar Blastomycosis in a Dog
Authors: Oshin Abimbola , Griffon Dominique , Lemberger Karin , Naughton James , Barger Anne
Published: September 2014

A 4-year-old, spayed female, mixed-breed dog was presented for evaluation of chronic left hind-limb lameness. Lytic lesions were observed in the left patella on radiographs of the stifle. A biopsy of the patella led to a histopathological diagnosis of blastomycosis. Surgical debridement followed by a 90-day course of itraconazole and physical rehabilitation resolved the clinical signs and stopped the progression of radiographic lesions. Blastomycosis should be considered as a differential diagnosis for stifle joint lameness with lytic lesions in the patella.
Situs Inversus Totalis in a Dog With a Chronic Diaphragmatic Hernia
Authors: Witsberger Tige H. , Dismukes David I. , Kelmer Efrat Y.
Published: September 2014

Situs inversus totalis is a rare, congenital condition that is characterized by the development of the thoracic and abdominal viscera in a mirror image to their normal orientation. This case report describes the condition in a 4-year-old, spayed female Doberman pinscher that was evaluated for dyspnea following sedation. Radiography confirmed a diaphragmatic hernia. Situs inversus was discovered during surgical correction. The diaphragmatic rent was repaired, and the dog was clinically normal at recheck 13 months after surgery.
Phimosis in Cats: 10 Cases (2000–2008)
Authors: May Lauren R. , Hauptman Joe G.
Published: September 2014

Medical records of 10 cats diagnosed with phimosis were reviewed. The most common clinical signs exhibited were stranguria and pollakiuria, which occurred in eight out of 10 cats. The diagnosis of phimosis was made from physical examination alone in all cats. Eight of the 10 cats had surgical widening of the preputial orifice. Seven of these eight cats had follow-up of ≥1 month, consisting of communications with the owner or referring veterinarian, who revealed resolution of preoperative clinical signs that were attributed to phimosis.
Clinical Anatomy and Surgical Repair of Prepubic Hernia in Dogs and Cats
Authors: Beittenmiller Menolly R. , Mann F. A. , Constantinescu Gheorghe M. , Luther Jill K.
Published: September 2014

Prepubic hernia is a traumatic hernia in small animals, most often associated with severe trauma to the caudal abdomen. Common causes include vehicular trauma, dog fights, and kicks by large animals. Rupture of the prepubic tendon in dogs and of its equivalent in cats results in a ventral abdominal hernia. Due to the traumatic nature of the injury, concurrent injuries are frequently seen. Clinical signs of herniation are often nonspecific, and the resultant hernia may not be readily apparent during routine physical examination. This being so, diagnosis is often based on a thorough physical examination in conjunction with abdominal radiography and, possibly, abdominal ultrasonography. Multiple methods of repair of prepubic hernia have been reported, and survival rates are quite good if concurrent injuries are not severe.
Primary Esophageal Squamous Cell Carcinoma in a Cat
Authors: Berube Danielle , Scott-Moncrieff J. Catharine , Rohleder Jacob , Vemireddi Vimala
Published: September 2014

Primary esophageal squamous cell carcinoma causing stricture was diagnosed in a cat via endoscopy and computed tomography. Difficulty in making this diagnosis via endoscopic biopsy alone is described. Although balloon dilatation was unsuccessful, supportive care via gastrostomy tube feeding and administration of piroxicam successfully allowed a 16-week survival from the time of presentation and a 4-week survival from the onset of treatment with piroxicam.
Punch Resection Alaplasty Technique in Dogs and Cats With Stenotic Nares: 14 Cases
Authors: Trostel C. Todd , Frankel Daniel J.
Published: September 2014

Punch resection alaplasty is a previously unreported surgical technique for the management of stenotic nares. Nine dogs underwent the procedure in conjunction with soft palate resection and/or laryngeal sacculectomy. Three dogs and two cats were treated with the novel punch resection alaplasty technique alone. Symmetrical resection was achieved, providing excellent cosmesis. Good to excellent results were achieved in all cases, with owners feeling that their pet’s overall well being was improved following surgery.
Primary Immune-Mediated Thrombocytopenia in Cats
Authors: Wondratschek Christina , Weingart Christiane , Kohn Barbara
Published: September 2014

Feline primary immune-mediated thrombocytopenia (pIMT) is a rare condition, and only a few cases have been described in veterinary literature. Five cats with severe thrombocytopenia most likely due to pIMT are described. A flow cytometry platelet-bound antibody test was positive in all cats; underlying diseases or triggering factors causing thrombocytopenia were not detected. Three cats were transfused with blood type-compatible fresh whole blood; one cat received Oxyglobin as well. All cats were treated with prednisolone; one cat received chlorambucil in addition. Four cats responded to treatment and were discharged from the hospital. One cat was euthanized due to dyspnea. Primary immune-mediated thrombocytopenia is rarely diagnosed in cats, but it is important as a differential diagnosis in cats presented with surface bleeding.
Confirmed 2,4-Dichlorophenoxyacetic Acid Toxicosis in a Dog
Authors: Chen Annie V. , Bagley Rodney S. , Talcott Patricia A.
Published: September 2014

A 2-year-old, intact male Weimaraner was evaluated for episodic extensor rigidity and a stiff gait of 24 hours’ duration. Percussion of the proximal appendicular muscles with a reflex hammer resulted in formation of dimples consistent with myotonia. Electromyography identified myotonic potentials. Residues of 2,4-dichlorophenoxyacetic acid (2,4-D) were detected in both serum and urine. The dog was treated with intravenous fluid therapy for 36 hours, and clinical signs improved dramatically. Toxicosis with 2,4-D should be considered a differential for acquired myotonia in dogs with or without systemic signs. Exposed dogs with only clinical signs of myotonia can have good clinical outcomes. A confirmed clinical case of 2,4-D toxicosis in the dog has not previously been reported.
Carboplatin Chemotherapy in a Cat With a Recurrent Anal Sac Apocrine Gland Adenocarcinoma
Authors: Wright Zachary M. , Fryer Jennifer S. , Calise David V. , Oliveira Fabiano N.
Published: September 2014

An 8-year-old, castrated male, domestic shorthaired cat was presented for evaluation of a perianal mass. The mass was incompletely excised, and histological assessment resulted in a diagnosis of anal sac adenocarcinoma. The cat had a partial response to carboplatin therapy but a short overall duration of response. Necropsy confirmed the original diagnosis as well as metastasis to the regional lymph nodes and lungs.
ESOPHAGEAL DYSFUNCTION IN DOGS WITH IDIOPATHIC LARYNGEAL PARALYSIS: A CONTROLLED COHORT STUDY
Authors: Stanley Bryden J. , Hauptman Joe G. , Fritz Michele C. , S.Rosenstein Diana , Kinns Jennifer
Published: September 2014

Objectives: To compare esophageal function in dogs with idiopathic laryngeal paralysis (ILP) to age- and breed-matched controls; to determine if dysfunction is associated with aspiration pneumonia over one year; and to compare clinical neurologic examination of dogs with ILP at enrollment and one year.

Study Design: Prospective controlled cohort study

Animals or Sample Population: 32 dogs with ILP, and 34 age- and breed-matched healthy dogs.

Methods: Three-phase esophagrams were performed on all dogs. Blinded analyses of the esophagrams were performed, and the mean esophageal score determined in each phase. Following unilateral crico-arytenoid laryngoplasty, dogs with ILP were re-examined including thoracic radiography at 1, 3, 6 and 12 months. Neurologic status was recorded at enrollment, 6 and 12 months.

Results: Esophagram scores in dogs with ILP were significantly higher in each phase compared to the controls, most notably with liquid (P<.0001). Dysfunction was more pronounced in the cervical and cranial thoracic esophagus. The 5 dogs that experienced aspiration pneumonia during the study period had significantly higher esophagram scores than the dogs that did not develop aspiration pneumonia (P<0.02). Ten of the 32 (31%) dogs with ILP had generalized neurologic signs upon enrollment and all (100%) dogs developed neurologic signs over one year (P<.0001).

Conclusions: Dogs with ILP also have esophageal dysfunction. Post-operative aspiration pneumonia is more likely in dogs with higher esophagram scores. Dogs with ILP will most likely develop generalized neuropathy over the course of a year.

Clinical Relevance: Esophagrams and neurologic examinations should be performed on all dogs with ILP.
Intraaxial Spinal Cord Hemorrhage Secondary to Atlantoaxial Subluxation in a Dog
Authors: Kent Marc , Eagleson Joseph S. , Neravanda Dharshan , Schatzberg Scott J. , Gruenenfelder Fredrik I. , Platt Simon R.
Published: September 2014

A 1-year-old, 3.5-kg, spayed female, toy poodle was presented for acute-onset tetraplegia and neck pain. Neuroanatomical diagnosis was consistent with a first through fifth cervical (C1 through C5) spinal cord lesion. Radiographs of the cervical vertebral column revealed atlantoaxial (AA) subluxation. Magnetic resonance imaging revealed abnormalities consistent with intraaxial spinal cord hemorrhage at the level of the AA articulation. The dog was treated with external coaptation. After 8 days, the dog regained voluntary motor function in all four limbs. Surgical stabilization was pursued. Postoperatively, the dog regained the ability to ambulate. This report details the imaging findings and management of a dog with intraaxial spinal cord hemorrhage secondary to AA subluxation.
Follicular Dysplasia of the Adult Doberman Pinscher
Authors: Moura Enio , Cirio Silvana M.
Published: September 2014

This paper presents the case of an adult female, red Doberman pinscher affected by permanent hypotrichosis, limited to the dorsolumbar region and sides of the trunk. The hypotrichosis began at approximately the age of 2 years and progressed slowly with no skin hyperpigmentation. The clinical and histopathological characteristics are of an uncommon form of follicular dysplasia.
Histopathological Confirmation of Polyneuropathy in 11 Dogs With Laryngeal Paralysis
Authors: Thieman Kelley M. , Krahwinkel D.J. , Sims Michael H. , Shelton G. Diane
Published: September 2014

Acquired laryngeal paralysis (LP) is an important cause of upper airway obstruction in dogs. We hypothesize that LP may be part of a generalized polyneuropathy complex. Electro-diagnostic studies were performed in six dogs, and histopathological studies of muscle and nerve biopsies were obtained from 11 dogs diagnosed with acquired LP. Abnormalities in electrodiagnostic procedures were consistent with a generalized polyneuropathy. Loss of large-caliber nerve fibers and axonal degeneration were identified in nerve biopsies, and neurogenic atrophy was observed in muscle specimens. Abnormalities in electrodiagnostic studies and histopathology provide evidence that LP may be part of a generalized polyneuropathy. Establishing a diagnosis of a more involved disease process is relevant for long-term prognosis.
Magnet Ingestion in Dogs: Two Cases
Authors: Kiefer Kristina , Hottinger Heidi , Kahn Tony , Ngo Mary , Ben-Amotz Ron
Published: September 2014

Two dogs that had ingested foreign bodies were presented with vomiting. The foreign bodies appeared as metal and dense on abdominal radiographs. Abdominal exploratory identified intestinal perforation in one case and gastrointestinal tissue trapped between the two foreign bodies adhered to each other in the second case. The foreign bodies were identified as magnets in one case and magnets and other metallic foreign bodies in the second case. Both dogs had excellent outcomes following surgical intervention. These cases demonstrate the danger of tissue entrapment between the foreign bodies as a result of the magnetic attraction between two objects. Dogs that are presented with a history of or are suspect for ingesting multiple magnets or a magnet and metal foreign bodies should be treated with surgical intervention because of the risk of gastrointestinal perforation as a result of magnetic attraction between the foreign bodies.
Cranial Vena Caval Thrombosis Associated With Endocardial Pacing Leads in Three Dogs
Authors: Murray John D. , O’Sullivan M. Lynne , Hawkes Kimberley C.E.
Published: September 2014

Three dogs were examined several years following implantation of transvenous, single-lead, endocardial, right-ventricular permanent pacing systems for signs consistent with cranial vena caval syndrome. Angiograms performed in all dogs revealed filling defects within the cranial vena cava and, in some instances, intracardiac filling defects. Medical therapy was instituted in two dogs, with one surviving several weeks. One dog underwent surgery to address intra-cardiac thrombosis but did not survive the immediate postoperative period. Postmortem examinations were performed in two dogs and confirmed cranial vena caval and intracardiac thrombosis. Cranial vena caval thrombosis associated with transvenous pacing leads appears to carry significant morbidity and mortality.
Pulmonary Paecilomyces lilacinus Infection in a Cat
Authors: Pawloski Danielle R. , Brunker Jill D. , Singh Kuldeep , Sutton Deanna A.
Published: September 2014

A 6-year-old, spayed female domestic shorthair cat was referred for an intermittent cough and wheezing of 3 to 4 months’ duration. Thoracic radiography revealed atelectasis of the right middle and caudal lung lobes with hyperinflation of the accessory lobe, consistent with bronchial obstruction. Bronchoscopy confirmed a narrowing of the right mainstem bronchial lumen; however, positive-pressure ventilation resulted in a severe pneumothorax. A lateral thoracotomy and right caudal lung lobectomy resulted in complete resolution of the pneumothorax and respiratory signs. Histopathology and culture of the lung revealed Paecilomyces lilacinus. The cat was placed on itraconazole therapy for 6 months. Since dismissal from the hospital, the cat has not exhibited clinical evidence of wheezing, coughing, or dyspnea and is neurologically normal.
Intraoperative Evaluation of the Larynx Following Unilateral Arytenoid Lateralization for Acquired Idiopathic Laryngeal Paralysis in Dogs
Authors: Weinstein Jeff , Weisman Debra
Published: September 2014

The purposes of this study were to describe a modified surgical technique in which intraoperative extubation was performed to evaluate abduction of the arytenoid cartilage prior to tying the suture and to assess outcome and complication rates associated with this procedure. Medical records from 30 client-owned dogs with acquired idiopathic laryngeal paralysis were retrospectively reviewed. All clients were contacted by telephone to obtain follow-up information regarding their dog. Six of the 30 surgeries required additional dissection (primarily around the craniodorsal aspect of the cricoarytenoid joint) after the initial intraoperative laryngeal examination. The procedures in 29 of the 30 dogs were deemed a success by the owners. Three (10%) dogs developed postoperative aspiration pneumonia. One of these dogs required long-term antibiotic therapy. Twenty-nine dogs returned to normal activity, and none of the dogs had any exercise intolerance associated with respiratory difficulties. Three owners reported that their dogs were able to swim, and one dog hunted postoperatively. Results of this study suggest that intraoperative laryngeal examination may help limit postoperative complications by allowing for direct, intraoral visualization of the arytenoid cartilage. This enables a surgeon to modify the soft tissue dissection around the cricoarytenoid joint to ensure that adequate abduction is apparent.
Thyroid Cancer in Dogs: An Update Based on 638 Cases (1995–2005)
Authors: Wucherer Katja L. , Wilke Vicki
Published: September 2014

The goal of this study was to update the descriptive statistics of thyroid cancer by using data from multiple institutions collected through the Veterinary Medical Database (VMDB). Information was collected and reported from cases of canine thyroid cancer submitted to the VMDB between January 1, 1995 and December 31, 2005. Odds ratio (OR) analysis was performed on breeds that had ≥3% of the total number of dogs with thyroid cancer; ORs for each age category were also determined. Thyroid cancer represented 1.1% of all neoplasms during the time period of interest. Golden retrievers, beagles, and Siberian huskies all had significantly increased ORs for developing thyroid cancer. No sex predisposition was evident, but dogs between 10 and 15 years of age had a significantly increased chance of developing thyroid disease. Carcinomas and adenocarcinomas represented 90% of thyroid cancers, while adenomas represented 9.3%. Thyroid carcinoma and adenocarcinoma continue to be uncommon in our canine population. Older dogs are still more commonly affected, and this study is in agreement with previous studies that golden retrievers and beagles are overrepresented. A new finding is that Siberian huskies are also overrepresented. Carcinomas represent a much higher proportion of thyroid cancers than previously reported, and adenomas are likely incidental findings on necropsy. Thyroid cancer should be high on the list of differentials for a neck mass in older, large-breed dogs, as they make up 1.1% of the cancer cases reported. The overwhelming majority of thyroid cancers are carcinomas, and they are most common in golden retrievers, beagles, and Siberian huskies.
Hypercalcemia of Malignancy in a Cat With Bronchogenic Adenocarcinoma
Authors: Schoen Keith , Block Gary , Newell Susan M. , Coronado George S.
Published: September 2014

A 16-year-old, neutered male, domestic shorthaired cat was presented with a history of progressive lethargy and decreased appetite. Serum biochemical profile demonstrated hypercalcemia, and thoracic radiographs and computed tomography were consistent with pulmonary neoplasia. A thoracotomy was performed, and a pulmonary mass was removed. Histopathology diagnosed a bronchogenic adenocarcinoma, and calcium levels returned to normal limits after excision of the mass. While bronchogenic adenocarcinoma has been a suspected cause for hypercalcemia in cats, to the authors’ knowledge, this is the first proven account.
Gamma-irradiated Calvarium Allograft Cranioplasty in a Cat Following Brain Tumor Removal
Authors: O’Brien Chad Seward , Bagley Rodney S. , Hicks Daniel G. , Chen Annie V. , Wininger Fred A. , Brumitt Jason W.
Published: September 2014

A 14-year-old domestic shorthair cat was evaluated for a 3-month history of head pressing and circling. Neurological examination suggested a supratentorial problem, predominantly on the left side. An extradural mass extending from the rostral frontal lobes caudally to the level of the caudal aspect of the corpus callosum was found with magnetic resonance imaging. A bilateral rostrotentorial craniectomy combined with a frontal sinus craniectomy was performed for mass removal. A gamma-irradiated calvarial allograft was used to repair the calvarial defect. At 14 months following surgery, the cat had no neurological abnormalities, and the skull and facial appearance was normal.
Externalized Ileocolic Anastomosis: Case Report
Authors: Simcock James , Kuntz Charles A. , Newman Raquel
Published: September 2014

A 6-year-old, spayed female Labrador retriever was presented 48 hours after an intestinal resection and anastomosis for management of a small intestinal foreign body. Abdominal ultrasound confirmed the presence of peritoneal effusion. Cytology of fluid collected by abdominocentesis revealed a large number of degenerate neutrophils with intracellular cocci. A diagnosis of septic peritonitis was made, presumably because of dehiscence of the anastomosis. Upon repeat exploratory celiotomy, the intestinal anastomosis (located 4 cm orad to the cecum) was found to be leaking intestinal contents into the abdomen. The distal ileum, cecum, and proximal colon were resected. An end-to-end, ileocolic anastomosis was performed and subsequently exteriorized into the subcutaneous space via a paramedian incision through the abdominal wall. The anastomosis was inspected daily for 4 days before it was returned to the abdomen and the subcutaneous defect was closed. Serial cytology of the peritoneal fluid, which was performed during this 4-day postoperative period, confirmed progressive resolution of peritonitis. The dog was discharged from the hospital 2 days following return of the anastomosis into the abdomen. Externalized intestinal anastomosis is used with good success in human medicine for repair of colonic injuries. In this case, externalization of the anastomosis permitted healing of the intestinal anastomosis in an environment isolated from the detrimental effects created by septic peritonitis. In addition, direct visualization of the anastomosis allowed assessment of healing. To our knowledge, this procedure has not been previously reported in companion animals.
Surgical Management of Diffuse Polypoid Cystitis Using Submucosal Resection in a Dog
Authors: Wolfe Tina M. , Hostutler Roger A. , Chew Dennis J. , McLoughlin Mary A. , Eaton Kathryn A.
Published: September 2014

A 6-year-old, spayed female Labrador retriever was presented with clinical signs of stranguria, pollakiuria, and hematuria of 12 weeks’ duration. A bacterial urinary tract infection, diffuse polypoid cystitis, and emphysematous cystitis were diagnosed. Antibiotic therapy combined with extensive resection of the mucosa and submucosa associated with polypoid lesions resulted in complete resolution of clinical signs and resolution of the remaining polypoid lesions. Polypoid cystitis is an uncommon but clinically relevant and reversible condition of the urinary bladder. Resection of mucosa and submucosa of the urinary bladder in dogs with polypoid cystitis may be a useful surgical treatment and can be considered as an alternative to partial cystectomy or mucosal resection.
Pneumothorax: A Review
Authors: Pawloski Danielle R. , Broaddus Kristyn D.
Published: September 2014

Pneumothorax is a pathological condition in which air accumulates within the thoracic cavity. Pneumothorax affects animals without sex or age predilections; however, it has been suggested that the Siberian husky breed of dog has a predisposition for spontaneous pneumothorax. Pneumothorax occurs as the result of trauma or underlying disease and can present a clinical challenge with regard to diagnostic and therapeutic techniques. Topics reviewed include normal lung physiology; the pathogenesis, diagnosis, treatment, complications, and prognosis of pneumothorax; and current techniques in animals and humans.
Peritoneopericardial Diaphragmatic Hernia: A Retrospective Study of 31 Cats and Eight Dogs
Authors: Banz Angela C. , Gottfried Sharon D.
Published: September 2014

The records of 31 cats and eight dogs undergoing surgical correction of peritoneopericardial diaphragmatic hernia (PPDH) from 2000 through 2007 were reviewed. Weimaraners and long-haired cats of varying breeds, particularly Maine Coon cats, appear to be at higher risk of PPDH. Presenting complaints were most commonly related to the respiratory and gastrointestinal tracts in both dogs and cats, although respiratory signs were more prevalent in cats, and gastrointestinal signs were more common in dogs. The most common herniated organs were liver, gallbladder, and small intestine. Mortality associated with surgical repair of PPDH in cats and dogs was low in the first 2 weeks postoperatively, and prognosis for return to normal function was excellent. Peri-and postoperative complications were typically minor and self-limiting.
Evaluation of Unilateral Arytenoid Lateralization for the Treatment of Laryngeal Paralysis in 14 Cats
Authors: Thunberg Brian , Lantz Gary C.
Published: September 2014

Laryngeal paralysis is a relatively common cause of upper airway obstruction in middle-aged to older, large-breed dogs; however, it is rare in the cat. The purpose of this study is to describe a series of cats diagnosed with laryngeal paralysis treated by unilateral arytenoid lateralization. Fourteen cats met the criteria of the study. Intraoperative and postoperative complications were seen in 21% (three of 14) and 50% (seven of 14) of cases, respectively. Median duration of follow-up was 11 months (range 3 weeks to 8 years). None of these cats had recurrence of clinical signs. Based on this brief case series, unilateral arytenoid lateralization appeared to be a suitable method for treating laryngeal paralysis in cats. Additional studies are warranted to determine the type and frequency of long-term complications.
Syndrome of Inappropriate Antidiuretic Hormone Secretion in a Cat
Authors: Cameron Kristin , Gallagher Alexander
Published: September 2014

A 3-year-old, spayed female, domestic shorthaired cat was presented for evaluation of liver disease. Following anesthesia, laparoscopy, and medical therapy, the cat developed severe hyponatremia that was unresponsive to fluid therapy. Further evaluation of serum and urine osmolality determined that the cat fulfilled the criteria for syndrome of inappropriate antidiuretic hormone secretion. Treatment with fluid restriction resulted in resolution of the hyponatremia and clinical signs associated with the electrolyte imbalance.
Canine necrotizing sialometaplasia: a case report and review of the literature
Authors: Brooks DG , Hottinger HA , Dunstan RW
Published: September 2014

Necrotizing sialometaplasia (NS) is a distinct, though rare disease of the salivary glands. Histologic findings in humans and dogs are identical, but the distribution of affected glands and clinical course are very different. Small terrier breeds are predisposed. Clinically, canine NS is characterized by nausea (i.e., ptyalism, lip smacking, gulping), dysphagia, and pain in the mandibular region. Surgical removal of the affected glands produces minimal, if any, improvement; however, transient administration of anticonvulsants has resulted in dramatic clinical improvement in three cases.
Mucinous oligodendroglioma of the spinal cord in a dog
Authors: Wilson RB , Beckman SL
Published: September 2014

Intraspinal neoplasia in the dog is relatively rare and may be classified according to the location of the tumor. Extradural tumors are situated outside the dura mater. Intradural tumors may be subdivided into two classes, depending upon whether the tumor is located outside the spinal cord in the subdural space (intradural extramedullary) or within the spinal cord substance (intramedullary). Intramedullary tumors are the least commonly reported spinal cord tumors; most primary intramedullary tumors are astrocytomas, ependymomas, or oligodendrogliomas. Reported here are the clinical, radiographic, and pathological findings associated with a spinal cord oligodendroglioma in a dog.
Ulcerative eosinophilic stomatitis in three Cavalier King Charles spaniels
Authors: Joffe DJ , Allen AL
Published: September 2014

Ulcerative eosinophilic stomatitis affecting three Cavalier King Charles spaniels is described. The lesions are similar in gross appearance to previously reported palatine eosinophilic granulomas, but histologically they lack granuloma formation. The cause of the lesions is not known. Treatment with corticosteroids led to the resolution of one case and partial resolution of a second. A third case resolved spontaneously without therapy.
Inhalant anesthetics and inspired oxygen: implications for anesthesia in birds
Authors: Ludders JW , Seaman GC , Erb HN
Published: September 2014

A number of factors cause respiratory depression in anesthetized birds. Hypoventilation can be due to anesthetic-induced depression of the central nervous system, muscular relaxation of the muscles of respiration, and effects on central and peripheral chemoreceptors. Compared to mammals, respiratory function in birds may be more sensitive to the effects of inhalant anesthetics because of their effect on unique carbon dioxide (CO2)-sensitive intrapulmonary chemoreceptors located within the avian lung. High fractions of inspired oxygen also contribute to hypoventilation, possibly by depressing oxygen-sensitive chemoreceptors. This article is a review of the factors that cause respiratory depression in anesthetized birds.
Concurrent lymphangioma, immune-mediated thrombocytopenia, and von Willebrand's disease in a dog
Authors: Woods JP , Johnstone IB , Bienzle D , Balson G , Gartley CJ
Published: September 2014

Lymphangioma, immune-mediated thrombocytopenia (IMT), and von Willebrand's disease (vWD) were diagnosed by histology, hematology, and a coagulation profile in a 14-month-old, female dachshund. Clinical and laboratory findings included ecchymotic inguinolabial swelling, thrombocytopenia, positive platelet factor-3 assay, prolonged buccal mucosal bleeding time, and subnormal von Willebrand factor antigen concentration and factor VIII activity. The IMT resolved with immunosuppressive glucocorticoid therapy. Histologic examination identified lymphangioma which was too extensive for surgical excision. The history and the clinical and laboratory findings were consistent with congenital vWD, although acquired vWD secondary to lymphangioma could not be ruled out.
Multiple metaphyseal involvement of a thymic lymphoma associated with hypercalcemia in a puppy
Authors: Barthez PY , Davis CR , Pool RR , Hornof WJ , Morgan JP
Published: September 2014

A six-month-old, female German shepherd dog was presented because of depression, anorexia, vomiting, polyuria, and polydipsia of approximately 10 days' duration. The puppy was depressed, and pain could be elicited on palpation of both shoulders and hips. The most significant results of serum chemistries and hematology were hypercalcemia; increased blood urea nitrogen, creatinine, and alkaline phosphatase; and leukocytosis with neutrophilia. Thoracic radiographs revealed a large thymic mass, diagnosed on histological examination as a thymic lymphoma. Radiographs of the shoulders revealed destructive bone lesions involving the proximal metaphyses of the humeri, causing slipped epiphyses. Bone lesions were found at necropsy on the proximal and distal aspects of both humeri and femurs. Bone resorption was due to local neoplastic infiltration and presumed humoral factors secreted locally and systemically by neoplastic thymic lymphocytes.
The canine cemented modular total hip prosthesis
Authors: Olmstead ML
Published: September 2014

Total hip replacement (THR) is well established as a treatment modality for dogs with noninfectious, nonneoplastic, disabling conditions of the coxofemoral joint. Since the mid 1970s, a fixed-head prosthesis has been used in this procedure. A modular prosthesis, which is based on many of the technical advances found in human prostheses, now is available for use in veterinary medicine. The prosthesis, surgical instrumentation, surgical technique, and clinical results have been evaluated in a prospective study conducted at The Ohio State University's College of Veterinary Medicine. The modular prosthesis provides results equal to or better than the fixed-head prosthesis.
Canine neosporosis: a case report and literature review
Authors: Ruehlmann D , Podell M , Oglesbee M , Dubey JP
Published: September 2014

A three-year-old, intact female vizsla presented for signs of an acute-onset, progressive spinal cord disease. Postmortem examination revealed multifocal central nervous system (CNS) lesions, severe pneumonia with pulmonary edema, and congestion of the liver. Protozoal cysts were found in multiple spinal cord and brain stem sections. Immunohistochemical staining positively identified these cysts as Neospora caninum. A literature review of Neospora caninum infection in the dog with summary of the pathogenesis, clinical signs, diagnostic evaluation, treatment success, and pathology is presented to provide the clinician with an overview of this increasingly prevalent disease.