bluuebunny/crossref_metadata_2025 huggingface dataset:
SHARIA FINANCIAL LITERACY FOR TEACHERS IN DARUL AMAN DISTRICT, ACEH TIMUR REGENCY
Authors: Ichsan Ichsan
Published: August 2022

This study aims to determine the Islamic financial literacy among teachers in Darul Aman sub-district, East Aceh Regency. It uses primary data obtained by distributing questionnaires to 80 respondents who were selected using Simple Random Sampling. The data analysis method used is simple linear regression. The data analysis method used is simple linear regression. The results partially show that Islamic financial literacy has a positive and significant effect on teachers in Darul Aman sub-district, East Aceh Regency. The results of the interview concludes that the knowledge of teachers in Darul Aman sub-district, East Aceh Regency on Islamic financial institutions is very good. Although they do not fully understand, they can already understand how the system is going on in Islamic financial institutions and conventional financial institutions, especially bank financial institutions
THE EFFECT OF FISCAL POLICY ON ECONOMIC GROWTH IN INDONESIA
Authors: Priyadipa Aril , Anwar Khairil , Darmawati Darmawati , Biby Sapna , Irfan Darul
Published: August 2022

This study was conducted in Indonesia within a period of 16 years from 2005-2020 using vector autoregression (VAR) analysis methods the purpose of this study to see the effect of fiscal policy (government revenue and expenditure) on economic growth, the results of the study obtained that using granger causality analysis that economic growth and government acceptance do not have a reciprocal relationship (causality) while government spending.  It has a reciprocal relationship (causality) to economic growth while by using the VAR method economic growth does not have a negative and significant effect on itself, government acceptance has a positive and significant effect on economic growth and government spending negatively and significantly limited economic growth.
PERAMALAN PRODUKSI DAN HARGA BAWANG PUTIH DI KABUPATEN LOMBOK TIMUR
Authors: Putri Bq. Lisa Indrawati , Zaini Anas , Anwar Anwar
Published: August 2022

This study aims to: (1) analyze the pattern of development of garlic production and prices in East Lombok Regency. (2) Analyzing the most suitable quantitative forecasting method to predict the production and price of garlic in the next 5 years in East Lombok Regency. The data used in this research is secondary data. Then to process the data used time series forecasting method. The pattern of production and price data shows that there is an element of trend and after viewing the ACF and PACF, it shows that the data is stationary. The best forecasting for production uses the Single Exponential Smoothing method because it has the smallest error value. The results of the production calculation show that the MAD value is 13,414, the MSE value is 477,560,765, and the MAPE value is 17% and has an average production value of 6.088.9 ton. While the results of the price calculation, the MAD value is 4,090, the MSE value is 31,075,403, and the MAPE value is 8%, but the results of price forecasting are relatively constant at Rp. 40,000.
Acute Coronary Syndrome in Patients with Diabetes mellitus: Features of the Course and Manifestations of Pain Syndrome
Authors: Halushko Oleksandr , Bolyuk Maryana
Published: August 2022

Acute coronary syndrome (ACS) remains a common cause of hospitalization for patients with diabetes mellitus (DM). Due to development of diabetic neuropathy, it is believed that this category of patients is characterized by a high frequency of atypical acute coronary syndrome, but data on this are quite contradictory.
The objective: to determine the features of the pain syndrome and its severity in patients with acute coronary syndrome and concomitant diabetes.
Materials and methods. The study involved 36 patients with diabetes (22 men and 14 women) aged 44–86 years, hospitalized urgently for ACS. Pain syndrome was assessed at the time of hospitalization and immediately after coronary artery revascularization according to the following criteria: visual analog scale (VAS), Numerical Rating Scale (NRS), clinical data, and biochemical markers.
Results. The majority of patients (91.67%) at the time of hospitalization complained of chest pain, the rest were not bothered by any pain. During the survey, patients described pain as «burning» (30.56%), «squeezing» (30.56%), «squeezing» (25.0%), «tingling» (5.56%). There were also complaints of difficulty breathing (13.89%), shortness of breath (11.1%), palpitations (41.67%). The appearance of excessive sweating was noticed by 16.67% of patients. There was no statistically significant difference between the results of pain assessment by VAS and NRS (p>0.1). The average value of glycemia at the time of hospitalization was 8.19±3.45 mmol/l (men – 8.17±3.61 mmol/l, women – 8.28±3.13 mmol/l). Glycemia greater than 10.0 mmol/l was detected in 8 patients, which was 22.22% of all patients. This category of patients was dominated by patients with severe pain (62.5%).
Conclusions. In patients with ACS and diabetes, the typical clinical picture of ACS prevailed (91.67% of patients) over the painless form. Prior to revascularization, moderate and severe pain occurred with equal frequency; there is no statistical difference between blood pressure, heart rate and glycemia (p>0.1) in patients with severe and moderate pain. Hyperglycemia (≥10.0 mmol/l) was found in 22.22%, among this category of patients was dominated by patients with severe pain.
Is Renoprotection Real for Patients with Hyperuricemia?
Authors: Khimion Liudmyla , Burianov Oleksandr , Nayshtetik Iryna , Rotova Svitlana , Smiyan Svitlana , Danylyuk Svitlana , Kicha Nataliia , Sytyuk Tetiana , Lebedeva Tetiana , Trophanchuk Viktoria
Published: August 2022

Number of patients with progressive chronic kidney disease (CKD) is increasing all over the world. One of the risk factors for CKD development and progression is increased serum uric acid (sUA) level. Possibly, control of hyperurcemia with urate lowering therapy drugs can slow the decline in kidney function.
The objective: to determine efficacy and safety of allopurinol and febuxostat in treatment of patients with CKD and hyperurcemia to reduce the sUA level and analyze its influence on glomerular filtration rate (GFR).
Materials and methods. The study included 45 CKD patients (stages 3b-5) without other severe/decompensated diseases and contraindications to the allopurinol/febuxostat. All patients underwent a comprehensive clinical and laboratory examination, and were divided into the study groups: Group I (28 patients, 61.3±3.2 y.o., CKD3b-12, CKD4-10, on hemodialysis-6 patients) received febuxostat, Group II (24 patients, 60.7Ѓ}4.1 y.o., CKD3b-9, CKD4-10, on hemodialysis – 5 patients) took allopurinol.
Results. Achievement of the target level of sUA was significantly often registered in Group I: after 1 month – in 45.5% (in group II – in 15.9%, p<0.001); after 3 months – in 67.5% (in group II – 21.2% p<0.01); after 6 months, these figures were 90% and 37.1%, respectively (p<0.01). sUA level <300 μmol/l was accompanied by significant positive GFR changes in group I patients; in group II there was a gradual progression of GFR deterioration in 31.8% of patients.
Conclusions. In patients with pre-dialysis stages of CKD febuxostat demonstrates renoprotective abilities. Use of febuxostat in patients with CKD stage 3b-4 and in patients on hemodialysis is safe and more effective for target sUA level achievement than the use of allopurinol.
Risks’ Stratification of Metabolic Disorders and Arterial Hypertension Depending on the NOS3 (RS2070744) and GNB3 (RS5443) Genes’ Allelic State
Authors: Sydorchuk Andriy
Published: August 2022

Early diagnosis of essential arterial hypertension (EAH), the search for risk factors for its occurrence and severity, which determine the metabolome and epigenetic structures activity, is an urgent task of modern medicine.
The objective: to assess the risks of metabolic disorders and the EAH occurrence, depending on the NOS3 (rs2070744) and GNB3 (rs5443) genes’ allelic state.
Materials and methods. 100 patients with EAH and 48 practically healthy (control group) were enrolled in the study. All participant underwent clinical and laboratory examinations. Metabolic changes were examined by blood glucose, total cholesterol (TC), triacylglycerol (TG), high and low density lipoprotein cholesterol (HDL-C, LDL-C), Atherogenicity index (AI). The NOS3 (rs2070744) and GNB3 (rs5443) genes were studied by real-time PCR. Risks, prognoses were determined by the clinical epidemiology method.
Results. The risk of metabolic disorders (dyslipidemia and hyperglycemia) in EAH patients does not depend on NOS3 gene polymorphism (rs2070744). However, the mutational T-allele of the GNB3 gene (825C>T) presence in the patients’ genotype increases the risk of hyperlipidemia due to atherogenic LDL-C 8.5 times [OR=8.45; OR 95%CI:0.99–72.70; p=0.05], with the CC-genotype protective role [OR=0.12; OR 95%CI:0.01–1.0; p=0.048].
The overall risk of EAH in the examined population increases with fasting hyperglycemia 9 times [OR 95%CI:2.86–27.08; p<0.001], with hypertriglyceridemia (>1.70 mmol/l) – 3 times [OR 95%CI:1.23–5.56; p=0.009] and with a decrease in HDL-C (<1.2 mmol/l) – more than 3.5 times [OR 95%CI:1.46–8.71; p=0.003], respectively.
Conclusion. The risk of metabolic disorders increases in EAH patients with the T-allele of the GNB3 gene (825C>T) 8.5 times with the lowest probability of such changes in the CC-genotype carriers [OR=0.12; p=0.048].
Obesity Prevention is the Key to a Nation’s Health
Authors: Mykhaylenko Volodymyr
Published: August 2022

The overweight and obesity is increasing problem for the health care system and for the health of the general population. The number of overweight people with varying degrees of obesity is growing in most countries around the world each year, a third of the world’s population suffers from this condition.
According to scientists, lack of sleep, stress, use of certain pharmacological drugs can lead to obesity. The causes and factors of weight gain are varied, not only in personal life, such as eating habits and physical activity, but also include factors that can not be controlled, such as environmental factors, socio-economic factors, genetic factors and more.
Obesity is a major risk factor for many diseases such as diabetes, cardiovascular disease, stroke and some cancers.
Obesity prevention should be one of the top priorities for the health care system. Preventive measures aimed to prevent the development of overweight and obesity have three levels of intervention: primary, secondary and tertiary. The purpose of the primary prevention is to minimize weight gain and prevent the development of overweight or obesity. Secondary prevention aimes to reduce the impact of the existing disease. Tertiary prevention concentraits on reduction of the complications that have developed as a result of the disease.
To prevent overweight and obesity, doctors advise to limit the caloric content of diet by reducing the consumption of fats and sugars; increase the consumption of fruits and vegetables, as well as whole grains and nuts; perform regular exercise.
Regular weighing by health professionals can help identify patterns and factors that contribute to weight gain. The success of obesity therapy depends on the patient’s trust to his doctor and the knowledge of the clinician in this area.
OVERVIEW OF LEARNING ANALYTICS DASHBOARDS AND ELEMENTS OF GAMIFICATION IN INTELLIGENT SYSTEMS FOR SELF-REGULATED LEARNING
Authors: Tytenko Sergiy , Halushko Alina , Demchyshyn Andrii
Published: August 2022

This article presents a systematic review of the research literature of the information panels of learning analytics, self-regulated learning and gamification, which report empirical results to assess the impact on learning and teaching. Also in this pape
КОНЦЕПЦИЯ ПОВЫШЕНИЯ СКОРОСТИ ДВИЖЕНИЯ ПОЕЗДОВ
Authors: Ковтун Павел , Шебзухов Юрий , Дубровская Татьяна
Published: August 2022

Путевое хозяйство – важнейшая отрасль железнодорожного транспорта республики, от состояния которой зависит работоспособность всей железной дороги. Нормальное функционирование путевого хозяйства невозможно без применения современных ресурсосберегающих техн
ЕКГ ДІАГНОСТИКА, ЯК ОДНА З ГОЛОВНИХ КОМПЕТЕНЦІЙ В ПРАКТИЦІ СІМЕЙНОГО ЛІКАРЯ – ШДЯХИ УДОСКОНАЛЕННЯ
Authors: Єфімова Наталія , Височина Ірина
Published: August 2022

Електрокардіографія (ЕКГ) – широко розповсюджений метод діагностики роботи серця в графічному зображенні, який дозволяє якнайшвидше виявити проблему в діяльності серця. В публікації представлено досвід проведення циклу тематичного удосконалення (ТУ) «ЕКГ
NUTRITIONAL VALUE OF FEED OF ALFALUM-CEREAL GRASSES DEPENDING ON FERTILIZATION IN THE CONDITIONS OF THE RIGHT BANK
Authors: Свистунова Ирина , Пошкребньов Віталій , Полторецкий Сергей , Гудзь Наталія , Тарасов Олександр
Published: August 2022

The results of research on the influence of mineral fertilizers on the nutritional value of forage of alfalfa grasses are presented. It was found that the application of nitrogen fertilizers significantly improves the supply of feed to digestible protein
ПОДАТКОВЕ СТИМУЛЮВАННЯ ІННОВАЦІЙНОЇ ДІЯЛЬНОСТІ
Authors: Нікітішин Андрій , Пасічний Микола
Published: August 2022

У статті розглядаються інструменти державного стимулювання інноваційних процесів у сучасних нестабільних політичних та економічних умовах, вплив податкових пільг на активізацію інноваційної діяльності в Україні. Обґрунтовано недостатнє використання держа
АКТУАЛЬНІ ПИТАННЯ ОРГАНІЗАЦІЇ ОБЛІКУ ОСНОВНИХ ЗАСОБІВ ЯК СТРУКТУРНИХ ЕЛЕМЕНТІВ СИСТЕМИ УПРАВЛІННЯ НЕОБОРОТНИМИ АКТИВАМИ ПІДПРИЄМСТВА
Authors: Гладій Ірина , Майстер Людмила
Published: August 2022

У статті обґрунтовано вагомість узагальнення інформаційного забезпечення щодо необоротних активів та основних засобів, зокрема, яке генерується обліковою системою підприємства. З ціллю вчасного прийняття правильних управлінських рішень стосовно необхіднос
ОЦІНКА СОЦІАЛЬНОЇ ВІДПОВІДАЛЬНІСТІ ЯК ОСНОВА ІННОВАЦІЙНОГО РОЗВИТКУ СУЧАСНОГО ПІДПРИЄМСТВА
Authors: Хачатрян Валентина , Стратійчук Вікторія
Published: August 2022

В роботі розглядаються особливості оцінки соціальної відповідальності сучасного підприємства. Застосовувано один з сучасних інноваційних методів управління –збалансовану систему показників, результатом застосування якого є побудова стратегічної карти. Зап
ІНТЕГРОВАНІ СТРУКТУРИ ЯК ОСНОВА ІННОВАЦІЙНОГО ПОТЕНЦІАЛУ
Authors: Селіщева Єлизавета , Шалімова Наталія
Published: August 2022

У статті досліджено особливості функціонування інтегрованих структур як основи інноваційного потенціалу. Зазначено, що на сьогодні інтегровані структури представлені великою кількістю форм. Доведено, що інтегровані структури сьогодні є однією з найбільш е
TESTING AS AN EFFECTIVE METHOD OF DIAGNOSING STUDENTS' EDUCATIONAL ACTIVITIES
Authors: Кропельницька Юлія , Велика Алла
Published: August 2022

The article traces the issues of advantages and disadvantages associated with the choice of testing as form control and knowledge diagnostics for students of higher medical education institutions studying medical chemistry
УМОВИ ПІДВИЩЕННЯ ПРОФЕСІЙНО-ПЕДАГОГІЧНОГО СПІЛКУВАННЯ МАЙБУТНІХ ВЧИТЕЛІВ НА УРОКАХ МУЗИКИ
Authors: Кайкова М.М. , Савранська О.М.
Published: August 2022

У статті виділено аксіоматичні фактори спілкування. Визначено функції педагогічного спілкування. Представлено класифікацію стиля ставлення викладача до студентів. Успішність та ефективність педагогічного спілкування майбутнього вчителя музики залежить ві
ПЕДАГОГІЧНЕ ПРОЕКТУВАННЯ ЯК УМОВА РЕАЛІЗАЦІЇ СПАДКОЄМНОСТІ МІЖ ДОШКІЛЬНОЮ І ПОЧАТКОВОЮ ОСВІТОЮ
Authors: Троян Н.Д.
Published: August 2022

У статті розглянуто теоретична модель проектування освітнього простору різними засобами з урахуванням сучасних умов, методів і засобів проектування. Упровадження у практику дошкільної освіти технології педагогічного проектування забезпечує створення спри
Synthesis, characterization, and evaluation of the antimicrobial activities of silver nanoparticles from Cyclotrichium origanifolium L.
Authors: AKTEPE Necmettin , ERBAY Nazım , BARAN Ayşe , BARAN M.firat , KESKİN Cumali
Published: August 2022

Cyclotricium origanifolium is a plant belonging to the Lamiaceae family and is a species that grows in the Western and Southern Anatolian regions of Turkey. In our study, the antimicrobial activities of silver nanoparticles (AgNP) were investigated through Cyclotricium origanifolium plant extract. Characterization processes of the obtained AgNPs, suitable spectral analysis methods; Uv-Vis was determined by FT-IR, SEM-EDX, XRD. According to the results of the analysis, it was determined that the AgNPs were spherical in shape and had an average diameter of 17.60 nm. The antimicrobial effect of AgNPs was determined by the minimum inhibition concentration (MIC) method. Gram positive as test microorganisms; Staphylococcus aureus, Bacillus subtilis and gram negative; Escherichia coli, Pseudomonas aeruginosa bacteria, and Candida albicans fungal pathogen species were used. The suppression of microorganism growth was investigated by comparing the efficacy of standard antibiotics used in our study with AgNPs produced by the green synthesis method. It has been observed that the obtained AgNPs have a very strong effect on gram-positive B. subtilis and gram-negative E. coli bacteria, and are more effective against C. albicans than the normal antifungal drug. It was determined that the antimicrobial activity of AgNPs produced from C. origanifolium L. plants showed a stronger effect than standard antibiotics.
Endostar Synergizes with Radiotherapy to Inhibit Angiogenesis of Cervical Cancer in a Subcutaneous Xenograft Mouse Model
Authors: Xu Zhonghua , Zhao Xianying , Shu Hang , Luo Weiwei , Dong Yaqing , Xu Lei , Zhu Haochen , Zhao Qihong , Lv Yin
Published: August 2022

Background: To investigate the synergic effect and underlying mechanism of Endostar, a recombinant human endostatin used for anti-angiogenesis, in radiotherapy for cervical cancer. Methods: The Cell Counting Kit-8 (CCK-8) assay and plate cloning experiment were first employed to analyze the proliferation of HeLa and SiHa cervical cancer cells and human umbilical vein vascular endothelial cells (HUVECs). Flow cytometry was used to detect apoptosis and cell cycle progression. A tube formation assay was used to assess angiogenesis in vitro. The expression of gamma H2A histone family member X (γ-H2AX) and activation of the vascular endothelial growth factor receptor (VEGFR) signaling pathway were detected by immunofluorescence and western blotting, respectively. In a HeLa xenograft model, tumor tissue expression of CD31 and alpha smooth muscle actin and serum expression of VEGF-A were detected by immunohistochemistry (IHC) and enzyme-linked immunosorbent assay, respectively. Results: The CCK-8 and plate cloning assays showed that Endostar and radiotherapy synergistically inhibited the growth of HUVECs but not HeLa and SiHa cells. The flow cytometric results showed that Endostar only promoted radiotherapy-induced apoptosis and G2/M phase arrest in HUVECs (p < 0.05). Endostar combined with radiotherapy also significantly inhibited tube formation by HUVECs (p < 0.05). Furthermore, Endostar inhibited the radiotherapy-induced expression of γH2AX (p < 0.05) and phosphorylation of VEGFR2/PI3K/AKT/DNA-PK in HUVECs (p < 0.05). IHC showed that Endostar enhanced the inhibitory effect of radiotherapy on the microvessel density in xenograft tumor tissues (p < 0.05), as well as serum VEGF-A expression (p < 0.05). The tumor volume in the combination therapy groups (1200 mm3) was significantly lower than in the control group (2500 mm3; p < 0.05). Conclusions: Our findings provide experimental evidence and a theoretical basis for the application of Endostar in combination with irradiation for anti-cervical cancer treatment.
Myectomy with and without Mitral Subvalvular Repair in Patients with Hypertrophic Obstructive Cardiomyopathy with Grade 3 to 4+ Mitral Regurgitation without Intrinsic Mitral Valve Disease: A Retrospective Observational Study
Authors: Liu Fangyu , Wang Yulin , Yang Ye , Lai Hao , Song Kai , Wang Chunsheng , Ji Qiang
Published: August 2022

Background: Hypertrophic obstructive cardiomyopathy (HOCM) with severe mitral regurgitation (MR) remains controversial for the choice of the concomitant mitral valve (MV) management versus septal myectomy alone. The impacts of different surgical strategies (concomitant mitral subvalvular procedures versus myectomy alone) on one-year results of surgical treatment of HOCM with grade 3 to 4+ MR without intrinsic MV disease were evaluated in this single-center, retrospective observational study. Methods: A total of 146 eligible patients were retrospectively screened into a combined group (n = 40) and an alone group (n = 106), depending on whether they underwent transaortic mitral subvalvular procedures. Perioperative outcomes were collected, and results at 1-year following surgery were compared. Results: Surgical mortality did not differ (0 for combined group vs. 0.9% for alone group, p = 0.538). Six patients (5.0% vs. 3.8%, p = 0.666) developed postoperative complete atrioventricular node block with permanent pacemaker implantation. No death or reoperation was recorded during a median follow-up of 18 months. At 1-year following surgery, (1) the provoked MR severity decreased from baseline in both groups with a significant difference between groups [1.0 (0–1.0) vs. 1.0 (1.0–1.3), p < 0.001]; (2) systolic anterior motion (SAM) was observed in 10 patients (0 vs. 10 in the alone group, p = 0.043); (3) the provoked gradient was also significantly lower than baseline value for each group, with a significant difference between the two groups (8.8 ± 4.3 mmHg vs. 12.1 ± 6.7 mmHg, p = 0.006); and (4) New York Heart Association class decreased from baseline value for each group (p < 0.001). Conclusions: In HOCM patients with grade 3 to 4+ MR without intrinsic MV disease, mitral subvalvular management during septal myectomy may be associated with a low incidence of SAM, improved MR, and a lower outflow tract gradient in comparison with septal myectomy alone.
Understanding recent tropospheric ozone trends in the context of large internal variability: A new perspective from chemistry-climate model ensembles
Authors: Fiore Arlene , Hancock Sarah , Lamarque Jean-Francois , Correa Gustavo , Chang Kai-Lan , Ru Muye , Cooper Owen , Gaudel Audrey , Polvani Lorenzo , Sauvage Bastien , Ziemke Jerald
Published: August 2022

Observational records of meteorological and chemical variables are imprinted by an unknown combination of anthropogenic activity, natural forcings, and internal variability. With a 15-member initial-condition ensemble generated from the CESM2-WACCM6 chemistry-climate model for 1950-2014, we extract signals of anthropogenic (‘forced’) change from the noise of internally arising climate variability on observed tropospheric ozone trends. Positive trends in free tropospheric ozone measured at long-term surface observatories, by commercial aircraft, and retrieved from satellite instruments generally fall within the ensemble range. CESM2-WACCM6 tropospheric ozone trends are also bracketed by those in a larger ensemble constructed from five additional chemistry-climate models. Comparison of the multi-model ensemble with observed tropospheric column ozone trends in the northern tropics implies an underestimate in regional precursor emission growth over recent decades. Positive tropospheric ozone trends clearly emerge from 1950 to 2014, exceeding 0.2 DU yr-1 at 20-40N in all CESM2-WACCM6 ensemble members. Tropospheric ozone observations are often only available for recent decades, and we show that even a two-decade record length is insufficient to eliminate the role of internal variability, which can produce regional tropospheric ozone trends oppositely signed from ensemble mean (forced) changes. By identifying regions and seasons with strong anthropogenic change signals relative to internal variability, initial-condition ensembles can guide future observing systems seeking to detect anthropogenic change. For example, analysis of the CESM2-WACCM6 ensemble reveals year-round upper tropospheric ozone increases from 1995-2014, largest at 30S-40N during boreal summer. Lower tropospheric ozone increases most strongly in the winter hemisphere, but internal variability leads to trends of opposite sign (ensemble overlaps zero) north of 40N during boreal summer. This decoupling of ozone trends in the upper and lower troposphere suggests a growing prominence for tropospheric ozone as a greenhouse gas despite regional efforts to abate warm season ground-level ozone.
Impact of Psychiatric Inpatient Readmission Location on Third Admission and Diagnostic Consistency
Authors: Pallas John
Published: August 2022

Background: The burden of readmissions after inpatient psychiatric hospitalization is high. Prior research indicates readmission with the same disorder within 30 days is between 9% and 15%. Objective: To identify the impact of inpatient readmission location on third admission and diagnostic consistency. Method: Retrospective study on inpatients in the Healthcare Cost and Utilization Project's 2019 National Readmissions Database with one or more hospital admission for a primary mood, substance, personality, schizophrenic or stress disorder. Readmission location was classified as ‘index’ if readmission was at the hospital of the first psychiatric admission, or ‘different’ if readmission was elsewhere. Rates of third hospital admission and primary diagnostic consistency were compared based on the location of readmission using a propensity score matching analysis. Results: A population of 22,722 inpatients was derived, half of whom were readmitted to a different than index hospital. The odds ratio of a third admission for a psychiatric disorder, comparing those admitted to a different hospital to those admitted to the index hospital, was 1.27 and significant. The odds ratio of a change in primary psychiatric diagnosis was 2.18 and significant. Conclusion: After controlling for propensity to be readmitted to a different than index hospital, those readmitted to a different than index hospital had a higher likelihood of being admitted a third time and a lower diagnostic consistency than those readmitted to the same hospital. Further study is warranted to understand the reasons for the difference in diagnostic consistency.
Pengelolaan Sungai Kelelawar Berdasarkan Aspek Ekologi-Sosial Budaya di Kecamatan Hulu Kuantan Kabupaten Kuantan Singingi, Provinsi Riau
Authors: Nurdiyana Rosita , Putra Ridwan Manda , Fauzi Muhammad
Published: August 2022

Sungai Kelelawar merupakan anak sungai dari Sungai Kuantan yang dimanfaatkan untuk berbagai kegiatan di sekitar desa Sungai Kelelawar. Kegiatan tersebut akan berdampak negatif jika tidak dikelola dengan baik. Oleh karena itu, perlu pemanfaatan sumber daya yang berbasis integrasi dan keberlanjutan berdasarkan aspek ekologi-sosial-budaya. Penelitian ini bertujuan untuk mengidentifikasi, menganalisis keberlanjutan pengelolaan Sungai Kelelawar, menentukan faktor-faktor keberlanjutan, dan merumuskan desain pengelolaan berdasarkan aspek Ekologi Sosial Budaya. Penelitian ini dilakukan pada bulan September-November 2021 dengan menggunakan metode survei. Atribut aspek ekologi adalah zona pemanfaatan sungai, kondisi perairan, kesuburan perairan (nitrat), keanekaragaman perifiton, organisme yang dilindungi (ikan), dan kunjungan wisata. Atribut aspek sosial budaya adalah tingkat pendidikan, fasilitas sosial, potensi konflik, kearifan dan pengetahuan lokal, tingkat partisipasi masyarakat, dan pengetahuan lingkungan. Data pengelolaan sungai dianalisis menggunakan aplikasi Rapfish. Hasil penelitian menunjukkan bahwa kondisi eksisting Sungai Kelelawar masih layak berdasarkan kesuburan air dan keanekaragaman perifiton. Indeks dan status keberlanjutan aspek ekologis termasuk dalam kategori kurang berkelanjutan dengan skor 32,9% dengan nilai monte carlo 34,6% sedangkan aspek sosial budaya cukup berkelanjutan dengan skor 51,2% dengan nilai monte carlo sebesar 50,4%.
Pengembangan Nugget Ikan Gulamah (Pennahia argentata) Sebagai Salah Satu Produk Perikanan di Kabupaten Indragiri Hilir
Authors: Rachman. B Arief , Hamisah Siti
Published: August 2022

Penelitian tentang Pengembangan Nugget Ikan Gulamah (Pennahia argentata)  dilaksanakan pada bulan Desember 2021 di jalan Harapan Ujung Kota Tembilahan Kabupaten Indragiri Hilir  dan Laboratorium Perikanan Universitas Islam Indragiri. Penelitian ini bertujuan untuk menghasilkan olahan nugget ikan dari bahan baku ikan gulamah (P. argentata).  Penelitian ini menggunakan metode pendekatan kualitatif dengan pembahasan penelitian dibahas secara deskriptif. Dari hasil penelitian, didapatkan ikan gulamah (P. argentata) dapat diolah menjadi nugget ikan. Hasil produk nugget ikan gulamah (P. argentata) dapat dikembangkan menjadi makanan cepat saji dan juga menjadi makanan beku. Hasil olahan ikan gulamah (P. argentata) ini dapat meningkatkan nilai jual hasil perikanan dan dapat dikembangkan menjadi usaha rumahan bagi istri nelayan sebagai produk perikanan
Pengaruh Larutan Benzalkonium Klorida dalam Air terhadap Sintasan Anakan Ikan Nila (Oreochromis niloticus)
Authors: Ayu Nurina
Published: August 2022

Benzalkonium klorida (BAC) merupakan surfaktan kationik yang memiliki kemanfaatan luas dan bersifat mudah terikat dengan materi hayati. BAC mampu menyebabkan efek toksik terhadap organisme perairan seperti ikan Oreochromis niloticus. Sebagai salah satu ikan yang paling banyak dikonsumsi oleh masyarakat Indonesia, pada masa pemeliharaannya, ikan ini juga berisiko terpapar BAC yang penggunaannya di Indonesia belum diregulasi dengan baik. Karenanya penelitian ini bertujuan untuk mengobservasi efek toksik BAC di air terhadap ketahanan O. niloticus yang dilihat dari angka sintasan setelah pemaparan selama 12 jam. Hasil menunjukkan kelangsungan hidup anakan O. niloticus terpengaruh secara signifikan ketika media hidupnya diberi larutan BAC. Angka sintasan yang diperoleh adalah 100%, 89%, 11%, 0% dan 0% untuk kelompok ikan yang secara berurutan terpapar BAC dengan konsentrasi 0 µg/L, 0,05 µg/L, 0,1 µg/L, 0,15 µg/L, dan 0,2 µg/L. Dapat disimpulkan bahwa konsentrasi BAC dalam air berbanding terbalik dengan angka sintasan anakan O. niloticus
Length-Weight Relationship and Sex Ratio Blood Clam (Anadara granosa) in Rangsang Barat Waters Kepulauan Meranti District, Riau Province
Authors: Efriyeldi Efriyeldi , Siregar Yusni Ikhwan , Siregar Sofyan Husein
Published: August 2022

Anadara granosa is one of the bivalves that are often found in public markets. This study aimed to study the relationship between length-weight and sex ratio of blood clams (A. granosa) in the coastal waters of West Rangsang. Sampling was carried out every month at three stations. Shells were collected from a 1 x 1 m2 plot on a quadratic transect. The relationship between length and weight was analyzed by regression analysis. The sex ratio between the number of female and male blood clams in each month of sampling was calculated and followed by the Chi square test to test the similarity. The results showed that the relationship between length and weight of A. granosa was positive allometric. The sex ratio of female and male blood clams in the waters of West Rangsang is not balanced. The number of male blood clams is more than the female.
Efektifitas Kelompok Pengolah Hasil Perikanan Pasca Program CCDP - IFAD Di Kota Parepare
Authors: Mahzar Farid , Ambar Abdul Azis , B Abdullah
Published: August 2022

Community empowerment through the CCDP - IFAD program is considered to be at least helpful in the efforts of the Regional Government to improve the standard of living of coastal communities, including those who still experience difficulties in gaining access to capital in the development of their productive economic activities. The purpose of the study was to analyze the effectiveness of fishery product processing groups after the CCDP-IFAD program ended in Parepare City. In assessing the effectiveness of the program, the study refers to the Decree of the Minister of Home Affairs No.690.900.327 of 1996. The results of the research group processing fishery products after the CCDP-IFAD program ended fairly effectively interms of availability of raw materials (83.52), production (84.21), and frequency of activities (83.90). Just a few groups of fishery products processors experienced increased productivity after the CCDP-IFAD programended.
Microplastic Identification of Tinfoil Barb (Puntius schawanafeldii) in Koto Panjang Dam Kampar Regency Riau Province
Authors: Margaretha Lily Sherly , Budijono Budijono , Fauzi Muhammad
Published: August 2022

Plastic waste can be found everywhere, including in the Koto Panjang Dam. As the plastic waste degraded, the microplastic materials may be distributed in the water and it may be accidentally swallowed by omnivorous fishes such as  Puntius schawanafeldii.  To understand the presence of the microplastic materials in the fish stomach, a research has been conducted in December 2020 - February 2021. The number of P.  schawanafeldii captured was 30 using fish net in 3-5 inch mesh size. The fish was dissected and the stomach was removed. Then the stomach content was added with 10% KOH andwas incubated for 2 weeks to delute the organic materials. Then was investigated under a binocular microscope to find out the microplastic materials. Results shown the type of microplastic present in the stomach of P. schawanafeldiiwas namely film, fibre, and fragment. The most common type of microplastic found was film, followed by fragments and fibre. The abundance of microplastic in the stomach of P.  schwanafeldii was around 2 – 15,8 particles/fish
Screening and Determination of Potential Cellulolytic Bacteria from Mangrove Ecosystem
Authors: Batubara Ummi Mardhiah , Suparjo Suparjo , Maritsa Hasna Ul , Pujianto Eko , Herlini Meli
Published: August 2022

The mangrove ecosystem is a coastal wetland resource that has a diversity of biodiversities such as flora, fauna, and microorganisms. Microbes are an important component in the mangrove environment not only play a role in creating and maintaining boosters but also work as a source of biotechnology products. Cellulolytic bacteria are a group of cellulase-producing bacteria capable of breaking down cellulose into glucose monomers, and cellulose as a source of carbon and energy. This study aims to screen and determine the diversity of cellulolytic bacteria from the mangrove ecosystem. The research method was experimentally by exploring the diversity of cellulolytic bacteria from soil and sediment from the mangrove ecosystem. Three sampling locations were selected, such as litter soil, soil in the root area, and soil in the tidal area. Screening of potential bacteria producing cellulase enzymes was carried out by growing bacteria on Carboxy Methyl Cellulose (CMC) agar medium which was cultured for 48 hours at 37°C. The bacteria that produced the greatest cellulolytic activity were characterized by their morphological and physiological characteristics. The results of bacterial characterization were then adjusted according to Bergey's Manual of Determinative Bacteriology. Based on the analysis showed three bacterial isolates were obtained that had the largest cellulolytic activity index, namely MS06 (9.73), MS08 (5.41), and MS02 (5.07). The results showed that three isolates had the same characteristics as the bacterial genera Bacillus, Cellulomonas, and Micrococcus.
Ekinakozit PC3 androjen bağımsız prostat kanseri hücrelerinde hücre proliferasyonunu azaltır ve hücre invazyonunu inhibe eder
Authors: SEÇME Mücahit , DODURGA Yavuz
Published: August 2022

Purpose: The aim of this study was to determine the effects of Echinacoside on cell proliferation, invasion and mRNA expression changes of invasion-related genes in PC3 androgen-independent prostate cancer cells.

Material Methods: The effect of Echinacoside on cell proliferation in PC3 cells was determined by XTT method. Anti-invasive efficacy was achieved using the transwell chamber. Total RNA isolation was performed by Trizol and cDNA was subsequently synthesized. mRNA expression changes of MMP2,MMP9, TIMP1, TIMP2 and TIMP3 were also performed in RT-PCR with SYBER Green.

Results: In this study, the IC50 dose of Echinacoside in PC3 cells was determined as 55.21 μM at 48th hour. It was determined that echinacoside inhibited cell invasion in PC3 cells and reduced the invasion by 66% in the dose group. In addition, it was found statistically significant that Echinacoside increased TIMP 1 mRNA expression 1.96 times, TIMP2 mRNA expression 2.60 times, while decreasing MMP2 expression 3.82 times and MMP9 mRNA expression 1.54 times.

Conclusion: In conclusion, it was revealed that echinacoside has an anti-proliferative effect on PC3 prostate cancer cells. It has also been shown that invasion-related genes can suppress invasion by regulating expression changes. With this study, preliminary data were presented in terms of detailed molecular biological studies to be carried out on echinacoside and its effect on prostate cancer.
CAUSES AND CONSEQUENCES OF AGE DISCRIMINATION - AGEISM OF THE ELDERLY IN THE INSTITUTIONAL SPACE
Authors: BALOGOVÁ Beáta , KOVALCHUK Julia
Published: August 2022

The presented professional article is devoted to the analysis of social aspects of the situation of elderly people in modern society. Its aim is to bring new knowledge about the quality of life and status of the elderly in Slovakia and Ukraine based on the analysis of this issue and to point out the causes and consequences of age discrimination of ageism in the institutional space (in social services for the elderly in Slovakia and Ukraine). The introduction of the article is the theoretical basis of the research, through which the author characterizes the period of aging and defines such concepts as population aging, quality of life, as well as the concept of ageism and others. It also describes the social services provided in the framework of social work in Slovakia and Ukraine (institutional care and pension scheme).The main tasks of a social worker in social work with the elderly are also revealed. One of them is the provision of appropriate professional assistance and care based on mutual trust, respect, empathy and respect for the point of view and needs of older people. The main starting point is respect for the person, which in principle does not change with illness, age or other factors. The social worker's competencies in caring for the elderly depend on the specific area of services in which the social worker works.It was found that social work with the elderly is based on a broader social context and ethical principles, which consists of a set of specific professional activities and services, designed for the elderly.The next part is discovering factors of internal and external environment, subjective and objective, which can be further classified into medical, psychological or socio-economic. The purpose of active preparation for elder age is to go through the last stage of life in the best physical and mental condition.Attention is drawn to the fact, that modern society perceives old age mostly negatively, which in turn leads to the fact that this negative vision in many cases is integrated into the minds of older people. Age discrimination is increasingly associated with health care or social services. The aim of this work was to draw attention to ageism in social work in the context of the scientific achievements of Slovakia and Ukraine. At the same time, we tried to pay attention to how social workers can contribute to the comprehensive rehabilitation of the elderly in the context of psychological and social impacts on the elderly in the paradigm of rejection of ageism.
SOCIAL MARKETING AS AN EFFECTIVE STRATEGY FOR SHAPING A HEALTHY LIFESTYLE AMONG YOUNG PEOPLE (THEORETICAL ASPECT)
Authors: Dziuba Nataliia
Published: August 2022

The formation of a healthy lifestyle of youth is one of the main objectives of Ukraine's youth policy. The strategy of forming the population's attitude to a healthy way of life is an important aspect of social prevention. The use of social marketing as an approach to the formation and implementation of social prevention strategies significantly increases the effectiveness of preventive measures. Social marketing focuses on the social context of decision-making and the use of theoretical methods to analyse the mechanisms of interaction in the public space. Current theoretical approaches to the explanation of human behaviour are the basis for the development of strategies aimed at the formation of a healthy way of life. These strategies are based on theories that explain changes in human behaviour, such as theories of deliberate action, planned behaviour, the theory of social learning, and others. Applying social marketing strategies involves the social environment and consumers' orientations analysis, the audience analysis and audience segmentation strategy, etc. Relevant theoretical concepts provide interpretation on behavioural decisions and behavioural patterns changes. Correspondingly social marketing utilizes variety of research approaches into the programs’ efficiency and their advanced testing, analysis of channels for developing distribution systems and advertising campaigns. Some commercial marketing techniques are applicable for the social marketing purpose. Among others are analysis of the target audience, identifying goals of desired behavioural changes, adaptation of messages and adaptation of strategies such as branding to facilitate the adoption and maintenance of safe behaviour in the health sector. The basic principles of social marketing can be seen as the messages targeted on the behaviour relevant to a healthy lifestyle should be different at different stages of program’ planning and implementation. Social marketing is used for the development and implementation of programs that contribute to a change in behaviour to socially beneficial, especially in the area of public health.
EXPERIENCE OF APPLICATION OF REMOTE PSYCHODRAMA IN SOCIAL WORK DURING A PANDEMIC CRISIS
Authors: Prozhoha Iryna
Published: August 2022

The article presents the experience of using psychodrama in an online format as a way of psychological assistance in a therapeutic group and social project during a pandemic. It is argued that in the conditions of force majeure, the timely provision of psychological assistance is of particular importance. The purpose of the article is to substantiate the use of remote psychodrama in social work during the pandemic crisis. In an online format, psychodrama is an effective way to provide psychological assistance. At the same time, differences from traditional psychodrama and the specifics of psychodrama online are revealed. The experiences of a person in quarantine are intensified, therefore, when conducting a psychodramatic game, ecological entry into the zoom space becomes important. The necessity of using the physical actions of the participants in a playful way to maintain the level of energy in the psychodramatic warm-up, which is a particularly important element in the work of an online psychodramatherapist, has been identified. Attention is focused on the fact that the main techniques of psychodrama, such as role reversal, duplication and mirror, take place not only in the usual format, but also remotely.It has been established that for group members an important part in the final phase of psychodrama is sharing, thanks to which the protagonist receives support and additional attention, and group members get the opportunity to relieve tension, emotional release, additional awareness and meaning. The following methods were used in the study: the method of psychotherapy and psychodrama in an online format. Results: the difficulties of adapting the psychodrama method to the virtual space are analyzed. As an example, psychodramatic games are described in the groups “Go through the crisis” and “Happiness in the palms”. Conclusions: remote psychodrama in the era of digital technologies occupies a worthy place among the methods of psychological assistance.
PRACTICAL ASPECTS OF THE IMPLEMENTATION OF THE STATE STANDARD OF SOCIAL SERVICE OF THE PREVENTION
Authors: Solnyshkina Alina
Published: August 2022

At the scientific article an author analyzed main points and provisions of the State Standard of the social service of the prevention. At the publication detailed scientific analysis is represented in such directions as: grades and levels of preventive measures, advantages and limitations of forms and methods of prevention in modern Ukrainian society. An author made accent on practical projects concerning realization and implementations of this Standard. The main and actual principles of provision of social service of prevention are analyzed in this article. Types of the prevention, resources for the implementation of this Standard to the practical activity of social centers are the main scientific priorities of this publication. An author analyzed directions of social service of the prevention and theoretical and practical approaches of provision and implementation of the programs meaningfully and structurally. Scientist analyzed main forms of submitting of the social service of the prevention such as: social advertising, lecture, video lecture hall, preventive conversation, social oriented debates, social and psychological trainings, The Theatre of Oppressed (Forum-Theatre), Methodology of “Living Library”, mass events, social flash mobs, social promotions. Also an author include to the content of this article peculiarities of involving of multidisciplinary team in the processes of the social prevention. All events and projects analyzed after learning of the main actual stages and levels of the social  prevention: primary level of the prevention, secondary level of the prevention, tertiary level of the prevention.
DIRECTIONS OF ACTIVITY OF THE GENDER CENTER IN THE CONDITIONS OF THE INSTITUTION OF HIGHER EDUCATION
Authors: Kravchenko Oksana , Voitovska Alla , Sarnatska Alina , Lysenko Anna
Published: August 2022

Educational programs and work programs on available educational content on gender issues are analyzed. The annual reports of the Gender Center are summarized. The content of the official websites of the Free Economic Zone has been studied. Surveys of participants in the educational process were conducted. A structural-functional approach was applied in order to highlight the activities of the Gender Center. Gender education has been implemented, which includes educational activities, dissemination and promotion of gender knowledge and gender culture, promotion of gender self-education through the implementation of non-formal education. Among the general competencies are: 1. The ability to exercise their rights and responsibilities as a member of society, to understand the values of civil (free democratic) society and the need for its sustainable development, the rule of law, human and civil rights and freedoms in Ukraine. Professional competencies include: 11. Ability to provide assistance and support to clients, taking into account their individual needs, age differences, gender, ethnicity and other characteristics. The practical experience of a higher education institution in the implementation of gender education in the training of future social workers is summarized. It was found that the most popular form of non-formal education are training programs, including "Tolerance towards the LGBT community", "Preparing young people for family life". The gender passport is the result of a gender analysis of the community and includes statistics disaggregated by article, as well as data obtained from the analysis of current municipal policies, the activities of local governments. Promising tasks of gender centers in higher education institutions are to substantiate recommendations for the introduction of educational components on gender issues based on the analysis of educational programs.