bluuebunny/crossref_metadata_2025 huggingface dataset:
Basel accord capital regulations and financial risk management: Empirical evidence from Pakistan’s financial institutions
Authors: Bashir Adnan , Khan Muhammad Waris Ali , Sajid Mirza Rizwan , Sorooshian Shahryar
Published: December 2022

The Pakistani banking sector has shown tremendous growth in the last two decades and witnessed strategic reforms including the implementation of Basel regulations. The objective of this study is to investigate the effect of Basel capital regulations on the various proxies of the financial performance of the Pakistani commercial banks. This study uses three different proxies to assess the effectiveness of the Basel capital regulations on the financial performance of Pakistani commercial banks from 2006 to 2018 and quantifies the effect of different Basel accords on the banking sector of Pakistan using the dynamic panel data estimation technique. In addition, the effect of the Global Financial Crisis (2008) on the financial performance of Pakistani banks has also been evaluated. The results indicate that Basel II and Basel III capital regulations have affected the banks’ profitability differently. Capital regulations of Basel II have increased the performance while capital requirements of Basel III have not affected the financial performance of Pakistani banks, pointing towards the ineffectiveness of Basel III capital regulations. Besides, there has been no change observed in the financial performance of Pakistani banks during the Global Financial Crisis (2008). Overall, the results of the Generalized Method of Moments (GMM) technique show that Basel capital regulations enhance the financial performance of the Pakistani banking sector.
Natural Polymer Based Floating Matrix Tablets of Domperidone
Authors: FR Sheeba , Sahani Amar , DB Yogesh
Published: December 2022

Aim: This study is aimed to prepare floating matrix Domperidone Maleate tablets by using natural polymers. Materials and Methods: Domperidone maleate was formulated as floating matrix tablets to increase the gastric residence time. Natural polymers like xanthan gum, tragacanth, sodium alginate along with sodium bicarbonate, citric acid and HPMC were used to increase the buoyancy time and decrease the floating lag time. The compressed tablets were evaluated for various parameters like friability, hardness, uniformity of weight, uniformity of drug content, swelling index, bouncy time and in-vitro drug release. Results: The evaluated parameters were in compliance with the pharmacopoeial limits. The most successful formulation was F2, containing xanthan gum as polymer. The drug release was extended up to 10 h which was close to that of theoretical release profile. Mathematical modelling of in-vitro dissolution data indicated the best-fit release kinetics was achieved with Zero order model with R2 values of 0.99. Conclusion: The prepared sustained-release floating tablets of domperidone maleate could perform therapeutically better than that of conventional sustained release tablets with improved efficacy and better patient compliance.
Formulation Optimization and Evaluation of Taste Masked Oro-dispersible Tablet of Levocetrizine Dihydrochloride by Ion Exchange Resin
Authors: Swati P Patil , Ashwini V Pati , M. M. Bari , S. D. Barhate , Nasir Mohd.
Published: December 2022

The aim of this study was to prepare ODT of taste masked levocetrizine dihydrochloride by using ion exchange resin. Levocetrizine Dihydrochloride is bitter in taste, Kyron T-134 a weak cationic exchange resin was used to mask the bitter taste of the drug. The ODTs were prepared by using drug-resin (DRC) complex using batch process. Compression of ODTs was done by using direct compression method with the technique of addition of superdisintegrants. Central composite design (CCD) was applied as an optimization technique. FTIR and DSC studies indicated drug and excipients were compatible with each other. The prepared orodispersible tablet blend and tablets were evaluated for various pre-compression and post-compression parameters. The Batch LH3 was given as optimized batch by central composite design. This optimized batch LH3 was passed all the pre-compression and post- compression parameters. The prepared ODTS showed successfully rapid onset of action with decrease in disintegration time 26 sec and %drug released was found to be 98.26%. It was concluded that levocetrizine dihydrochloride ODTs were prepared successfully by taste masking method using Kyron T-134 ion exchange resin and croscarmellose sodium as Superdisintegrant using CCD. AS per CDER guidelines, it shows DT within 5-30 sec.
Solubility Enhancement of Resveratrol by Effervescence Assisted Fusion Technique
Authors: Tawar Mukund , Raut Kiran , Chaudhary Reshma , Jain Nikita
Published: December 2022

The basic reason behind this study was to enhance the solubility rate of resveratrol which will finally enhance the dissolution i.e. the rate of drug release due to which the absorption of the drug will increase. The method applied here was effervescent assisted fusion technique. Various batches were prepared by employing water soluble carrier and sodium bicarbonate. The results obtained from the study revealed that the solubility of the drug can be increased up to 10 times than compared with the pure drug in various solvents i.e. phosphate buffer and distilled water. The compatibility study showed no interaction between drug and the excipient while the micromeretics property showed good flow property with good compressibility property. The percent yield of the dispersions prepared ranges between 79.20±0.28% - 89.38±0.25% while the drug release data showed a better rate of drug release than compared with the pure drug which ranges between 10.87% - 99.14%. The pure drug was having a drug release of less than 70% while the optimized batch F5 was having a drug release of more than 95% in the specific period of time. The XRD data showed that the drug’s crystalline structure was not hampered during the preparation while the SEM data revealed the surface shape of the pure drug which was tile shaped and the prepared dispersion was of flakes like formation. From the study it can be concluded that the methods employed in this study can be proven to be a excellent method for enhancing the solubility of the drug up to 10 folds.
Analytical Methods of Antidiabetic Drugs – Sitagliptin, Saxagliptin, Linagliptin, Alogliptin, Gemifibrozil, Troglitazone, Pioglitazone and Rosiglitazone: A Review
Authors: Varma. D. S. , Dighe P. R.
Published: December 2022

Analytical techniques used to determine chemical or physical property of analyte, chemical substance, chemical element or mixture. There are different types of analytical techniques used in pharmaceutical field for qualitative and quantitative estimation of drugs in biological fluids such as human plasma, human serum, human urine etc. and its formulations such as tablet, capsule, bulk drugs etc. This review work aims to provide most of existing analytical methods for analysis of Dipeptidyl peptidase-4 (DPP4) inhibitor and Peroxisome proliferator activated (PPAR) agonist. Estimation of Sitagliptin, Saxagliptin, Alogliptin, Gemifibrozil, Troglitazone, Pioglitazone, Linagliptin, and Rosiglitazone in active pharmaceutical ingredients, biological fluids and in various formulations which is reported in various research articles are reviewed. The analytical techniques which are utilised for the estimation of these drugs involves RP-HPLC, HPTLC, UPLC-MS/MS, LC-MS/MS, MALDI-TOF mass spectrometry, Raman spectroscopy, Liquid chromatography and Tandem mass spectrometry, TLC-densitometry with fluorescent detector, LC-ESI-MS-MS etc. are involved. The review assist in appropriate selection of analytical technique, mobile phase, column and detector based on available analytical instruments and chemicals by referring tabulated extensive condition. DPP4 inhibitor used in treatment of type 2 diabetes, hypoglycemia, weight loss etc. PPAR agonist also used in treatement of type 2 diabetes, in metabolic syndrome mainly for lowering triglycerides and blood sugar etc.
Kết quả sớm của tán sỏi nội soi bằng ống soi mềm kỹ thuật số điều trị sỏi tiết niệu tại Bệnh viện Đại học Y Hà Nội
Authors: Long Hoàng , Bắc Nguyễn Đình
Published: December 2022

Mục đích của nghiên cứu này là đánh giá kết quả sớm của tán sỏi nội soi bằng ống soi mềm kỹ thuật số trong điều trị sỏi tiết niệu. Chúng tôi tiến hành một nghiên cứu mô tả hồi cứu từ tháng 6/2021 đến tháng 6/2022. Nghiên cứu này gồm 84 bệnh nhân, tuổi trung bình là 49,9 ± 13,6 tuổi, tỷ lệ nam và nữ lần lượt là 67,9% và 32,1%. Kích thước trung bình của sỏi là 12,6 ± 3,3mm. Có 69% bệnh nhân không cần đặt JJ trước tán sỏi và 31% bệnh nhân phải đặt JJ, trong đó nguyên nhân chính là do hẹp niệu quản. Có 2 cỡ Sheath niệu quản được sử dụng là 12F và 14F với tỷ lệ lần lượt là 95,2% và 4,8%. Chỉ có 1 bệnh nhân (1,2%) không đặt JJ sau tán sỏi và 98,8% bệnh nhân còn lại được đặt JJ trong đó đa số bệnh nhân được đặt JJ số 6 (63,1%). Tỷ lệ sạch sỏi ngay sau phẫu thuật là 88,1% và tỷ lệ này sau 1 tháng là 91,7%. Thời gian phẫu thuật trung bình là 56,4 ± 14,5 phút và thời gian nằm viện trung bình là 1,4 ± 1,1 ngày. Tỷ lệ biến chứng độ I và II theo phân loại Clavien-Dindo lần lượt là 7,2% và 8,4%, chúng tôi không ghi nhận bệnh nhân nào có biến chứng từ độ III trở lên. Như vậy, TSOM là một phương pháp có tỷ lệ sạch sỏi cao, trong khi đó tỷ lệ các biến chứng sớm thấp trong điều trị các trường hợp sỏi tiết niệu ≤ 20mm.
Chất lượng noãn, phôi và kết quả có thai của phác đồ kích thích buồng trứng nhẹ so với phác đồ kích thích buồng trứng liều cao ở bệnh nhân giảm dự trữ buồng trứng
Authors: Yến Trịnh Thị Ngọc , Tùng Dương Tiến , Minh Hồ Nguyệt , Hà Nguyễn Mạnh
Published: December 2022

Nghiên cứu hồi cứu trên nhóm bệnh nhân giảm dự trữ buồng trứng được kích thích buồng trứng bằng phác đồ nhẹ và phác đồ liều cao nhằm so sánh chất lượng noãn và phôi thu được ở hai phác đồ này. Kết quả cho thấy, tổng số noãn và số noãn trưởng thành MII trung bình thu được của nhóm phác đồ kích thích buồng trứng nhẹ (3,92 ± 2,33 noãn, với 2,86 ± 2,17 noãn MII) ít hơn đáng kể so với nhóm kích thích buồng trứng liều cao (5,90 ± 2,29 noãn, với 4,26 ± 2,14 noãn MII). Số lượng phôi ngày 2 của nhóm phác đồ nhẹ cũng ít hơn so với phác đồ liều cao (3,38 ± 1,99  so với 4,08 ± 1,76 phôi), tuy nhiên không có sự khác biệt về số lượng phôi độ I giữa hai nhóm này. Tỷ lệ có thai, tỷ lệ thai lâm sàng và tỷ lệ thai diễn tiến không có sự khác biệt giữa hai nhóm. Như vậy, kích thích buồng trứng nhẹ là cách tiếp cận tiềm năng dành cho bệnh nhân giảm dự trữ buồng trứng.
Một số yếu tố liên quan đến thời gian khởi phát - nhập viện ở bệnh nhân đột quỵ nhồi máu não cấp
Authors: Hiển Phạm Hữu , Hải Hoàng Bùi
Published: December 2022

Nghiên cứu nhằm mô tả một số yếu tố liên quan đến thời gian khởi phát - nhập viện (từ lúc bệnh nhân xuất hiện triệu chứng đầu tiên đến khi bệnh nhân nhập viện) ở bệnh nhân đột quỵ nhồi máu não cấp. Đây là nghiên cứu cắt ngang tại Bệnh viện Đại học Y Hà Nội và Bệnh viện Đa khoa Hà Đông trên 214 bệnh nhân trong thời gian từ 7/2021 - 8/2022 được chẩn đoán đột quỵ nhồi máu não cấp. Kết quả cho thấy thời gian khởi phát - nhập viện trung vị là 8,8 giờ (tứ phân vị 1,87 - 66 giờ, sớm nhất là 0,5 giờ và muộn nhất là 144 giờ), có 37,9% bệnh nhân nhập viện trước 6 giờ. Phân tích đơn biến cho thấy có 9 yếu tố liên quan đến thời gian nhập viện < 6 giờ: học vấn trên THPT (OR = 3, 95%CI: 1,4 - 6,5), cán bộ viên chức/hưu trí (OR = 2,6, 95%CI: 1,5 - 4,6), điểm NIHSS ≥ 16 (OR = 8,3, 95%CI: 4,1 - 16,8), có người chứng kiến (OR = 2,6, 95%CI: 1,4 - 4,6), có tìm sự trợ giúp (OR = 6,1, 95%CI: 3,3 - 11,2), có gọi cấp cứu 115 (OR = 8,3, 95%CI: 2,3 - 30,1), vận chuyển bằng xe cấp cứu (OR = 8,3, 95%CI: 2,3 - 30,1), khoảng cách đến viện < 10km (OR = 1,8, 95%CI: 1 - 3,2), có kiến thức về đột quỵ (OR = 6,6, 95%CI: 2,7 - 16,3). Phân tích đa biến cho thấy có 2 yếu tố chính liên quan đến thời gian nhập viện < 6 giờ là: điểm NIHSS ≥ 16 (OR = 4,4, 95%CI: 1,8 - 10,3), và có tìm sự trợ giúp (OR = 4,1, 95%CI: 1,9 - 8,4).
Konuşma Duygu Tanıma için Akustik Özelliklere Dayalı LSTM Tabanlı Bir Yaklaşım
Authors: DONUK Kenan , HANBAY Davut
Published: December 2022

Konuşma duygu tanıma, konuşma sinyallerinden insan duygularını gerçek zamanlı olarak tanıyabilen aktif bir insan-bilgisayar etkileşimi alanıdır. Bu alanda yapılan tanıma görevi, duyguların karmaşıklığı nedeniyle zorlu bir sınıflandırma örneğidir. Etkili bir sınıflandırma işleminin yapılabilmesi yüksek seviyeli derin özelliklere ve uygun bir derin öğrenme modeline bağlıdır. Konuşma duygu tanıma alanında yapılmış birçok sınıflandırma çalışması mevcuttur. Bu çalışmalarda konuşma verilerinden duyguların doğru bir şekilde çıkarılması için birçok farklı model ve özellik birleşimi önerilmiştir. Bu makalede konuşma duygu tanıma görevi için bir sistem önerilmektedir. Bu sistemde konuşma duygu tanıma için uzun-kısa süreli bellek tabanlı bir derin öğrenme modeli önerilmiştir. Önerilen sistem ön-işlem, özellik çıkarma, özellik birleşimi, uzun-kısa süreli bellek ve sınıflandırma olmak üzere dört aşamadan oluşmaktadır. Önerilen sistemde konuşma verilerine ilk olarak kırpma ve ön-vurgu ön-işlemleri uygulanır. Bu işlemlerden sonra elde edilen konuşma verilerinden Mel Frekans Kepstrum Katsayıları, Sıfır Geçiş Oranı ve Kök Ortalama Kare Enerji akustik özellikleri çıkarılarak birleştirilir. Birleştirilen bu özelliklerin uzamsal bilgilerinin yanında zaman içindeki akustik değişimleri sistemde önerilen uzun-kısa süreli bellek ve buna bağlı bir derin sinir ağı modeliyle öğrenilir. Son olarak softmax aktivasyon fonksiyonu ile öğrenilen bilgiler 8 farklı duyguya sınıflandırılır. Önerilen sistem RAVDESS ve TESS veri setlerinin birlikte kullanıldığı bir veri kümesinde test edilmiştir. Eğitim, doğrulama ve test sonuçlarında sırasıyla %99.87 , %85.14 , %88.92 oranlarında doğruluklar ölçülmüştür. Sonuçlar, son teknoloji çalışmalardaki doğruluklarla kıyaslanmış önerilen sistemin başarısı ortaya konmuştur.
Karcı Sinir Ağlarının Uygulaması ve Performans Analizi
Authors: KARAKURT Meral , OYMAK Elif Aslı , HARK Hulya , ERDOĞAN Mehmet Can , KARCİ Ali
Published: December 2022

Yapay Sinir Ağları (YSA), matematik ve mühendislik problemlerinin çözümünde sıkça kullanılmaktadır. YSA, canlıların beyin sinir hücresinden esinlenerek ortaya atılan ve bir ya da birden fazla nöronun belirli disiplin çerçevesinde bir görevi yerine getirmesini sağlayan matematiksel modeldir. YSA’ların eğitimi aşamasında probleme göre değişebilen gizli katman sayısı, ağırlıklar, öğrenme katsayısı ve daha birçok parametre kullanılmaktadır. Bu çalışmada, Karcı Sinir Ağı (Karcı Neural Network -Karcı NN) olarak adlandırılan ve YSA’nın öğrenmesi aşamasında kullanılan öğrenme katsayısının kullanımı yerine kesir dereceli türev kullanılan yeni bir hesaplama yöntemi kullanılmıştır. Karcı NN yöntemiyle yapılan deneysel çalışmalar sonucunda, özellikle alfa parametresinin 1.4 değeri için hata oranının % 0.019 olarak ölçüldüğü başarılı sonuçlar elde edilmiştir.
Fundamentación de una posible teología natural desde una clave tomista
Authors: Rodríguez Cillero Alberto Jesús
Published: December 2022

Nuestro objetivo en este artículo es presentar los fundamentos de la teología natural desde una clave tomista, que podríamos sintetizar en la respuesta a la pregunta: ¿es posible para el hombre llegar a Dios con la sola razón? En la Encíclica Fides et Ratio el Papa Juan Pablo II lanzó a la Iglesia un desafío para que se diera, de manera clara y concisa, aunando fe y razón, una respuesta al mundo moderno sobre los grandes interrogantes que pesan sobre el hombre. Propone el Papa recuperar la philosophia perennis, de los doctores de la escolástica. Una filosofía asentada en los primeros principios de la razón; principios que santo Tomás de Aquino conocía bien, y cuya comprensión será de vital importancia, a fin de comprender su pensamiento.
Association of Post-Operative Infection and MI with Metabolic Syndrome after Coronary Artery Bypass Graft
Authors: Kibriya Ghulam , Abbas Amna , Aftab Hina , Akram Muhammad Athif , Saeed Yahya , Iqbal Omar , Iqbal Azhar
Published: December 2022

Objective: To find out association of metabolic syndrome with early outcomes e.g.(post operative infection, acute kidney injury, and MI) after CABG. Study Design: This was a comparative study. Place and Duration: This study was performed from the first of July 2020 to the first of January 2021 at the Cardiac Surgery Department, PIC, Jail Road, Lahore Methodology: This comparative study performed from the first of July 2020 to the first of January 2021 at the Cardiac Surgery Department, PIC, Jail Road, Lahore. The approach of non-probability sampling was applied. After obtaining consent on a consent form, 172 Patients (86 in the exposed group and 86 in the non-exposed group) were included. Results: The average age of the participants in this study was 55.30 ± 8.77 years; there were 130 cases (75.6%) of men and 42 cases (24.4%) of women. There were 56 (65.12%) men and 30 (34.88%) women in the exposed group, compared to 74 (86.05%) men and 12 (13.95%) women in the non-exposed group. Post-operative MI was statistically insignificant in both groups, p-value >0.05, renal failure and postoperative infection were statistically significant. Conclusion: Because many MetS syndrome factors are under our control, it is important to prevent it early especially in cases of CABG, to get better outcomes. Although we noted that renal failure and postoperative infection were statistically high in exposed groups, with a p-value of 0.05, and MI was statistically similar in both groups, with a p-value of >0.05, the outcomes of the current study were quite different and unexpected. Further studies are suggested to be done on a larger scale. Keywords: CABG, Lipid Profile, Diabetes, Obesity, Mortality
Prevalent Estimates of HIV/AIDS in Chronically Ill patients admitted in JPMC Karachi Pakistan
Authors: Anwar Muhammad , Rahat Noshaba , Shahzad Humera , Qudos Amtul
Published: December 2022

Objective: To find out the prevalence of HIV/AIDS in chronically ill patients admitted in tertiary care hospital JPMC(Jinnah Postgraduate Medical Centre) Karachi. Study design & place: This cross-sectional study was conducted at JPMC during the June, 2021 to April, 2022. Materials & Methods: A total of 500 patient age ≥18 years having highly suspicious history & symptoms of HIV/AIDS, admitted in Medical & pulmonology department were included in this study. A well-structured questionnaire was used to obtain background characteristics, clinical symptoms; history of high risk behaviors and I/V drug use of all participants was collected. Confidentiality was assured of all participants given unique identification number. Data was analyzed by using Statistical Package for Social Sciences version 21 (SPSS 21). Results: A total of 500 patients comprised of 373 (74.6%) male and 127 (25.4%) female, male to female ratio was 2.93:1. The mean age was 33.5 ± 12.78 years (18 to 83 years). We observed that most of patients belong with history of blood transfusion, 160 (32%) followed by I/V drug user 130 (26%) and sexual contact 96 (19.2%) cases. Out of 500 study participants, 29(5.8%) subjects were HIV/AIDS positive. The results of this study will provide information and awareness about the transmission of HIV in community. The study revealed that the blood transfusion is a significant risk factor in transmission of HIV. The findings of current study will help doctors for postoperative pain treatment following major abdominal surgery. Acute pain management in hospitals faces some significant obstacles, according to a recent review on postoperative pain management procedures in tertiary care facilities center. Conclusion: Most of the chronically ill patients admitted were men who had been diagnosed with HIV/AIDS. Blood transfusion history, intravenous drug use, and multiple sex partners were important risk factors. There is a need to create awareness among the general public about the risk factors for HIV/AIDS to decelerate the spread of this deadly disease. Keywords: AIDS Acquired immunodeficiency syndrome Chronic diseases, HIV Human Immunodeficiency Virus, Injecting drug user, Multiple sex partners, JPMC Jinnah Postgraduate Medical Centre
Perinatal Outcome in Patients with Borderline AFI
Authors: Sadia Salma , Akram Nishat , Gull Sana , Aftab Hina , Akram Muhammad Athif , Kanwal Rehana , Shahzad Hafiz Irfan
Published: December 2022

Background: During pregnancy, amniotic fluid indicates the normal placental function. It is the most essential element for surveillance of fetal growth and health. Amniotic fluid index (AFI) is the most ideal way to determine the level of amniotic fluid during pregnancy. However, the single deepest pocket is applied to determine the changes in AFI level in pregnancies suspected to oligohydramnios. Borderline AFI is defined as AFI levels > 5 to < 10cm; it is a challenging task in obstetrics to associate it with adverse pregnancy outcomes. Objective: To assess the perinatal outcomes in patients with borderline AFI. Study Design: Cross-sectional. Setting: Department of Obstetrics & Gynaecology, Sharif Medical City Hospital, Lahore. Study Duration: Study was carried out over a period of six months from 10-11-2020 to 11-05-2021. Subjects And Methods: A total of 160 patients having borderline AFI (more than 5 and less than 10cm) were included in the study. Perinatal outcomes were assessed at the time of delivery in the hospital. Data Analysis Method: Stratification of data was carried out with regard to age, gestational age, parity and area of residence. Results: Mean age of the patients was 25.17±4.90 years. Mean gestational age was observed to be 38.44±1.54 weeks. Majority of the patients were between Para 0 to 3. There was no smoker in preset study. Most of the patients belonged to rural area. Perinatal outcomes were as follows: Intrapartum fetal distress was observed in 64 (40%), meconium staining in 56 (35%), Apgar score < 10 at 5 minutes in 37 patients (23.1%) and NICU admission in 38 (23.8%). Conclusion: In conclusion, borderline AFI during pregnancy can lead to severe hazardous consequences. Therefore, pregnancy complicated with borderline AFI must be observed carefully in order to improve the outcome of pregnancy and avoid adverse perinatal outcomes. Keywords: Borderline AFI, Apgar Score, NICU Admission, Intrapartum Fetal Distress, Meconium Staining.
Impact of Delayed Presentation on the Surgical Outcome of Epidural Hematoma in Traumatic Brain Injury Patients
Authors: Iqbal Arshad , Ali Taimoor , Anwarullah Muhammad , Ziaullah Qazi
Published: December 2022

Objectives: To note the impact of delayed presentation on the surgical outcome of extradural hematoma in traumatic brain injury. Study Design: A case-series study. Place Duration of the Study: Department of Neurosurgery, Lady Reading Hospital Peshawar from July 2018 to June 2019. Methodology: A total of 119 patients of both genders aged 15-45 years suffering from epidural hematoma with history of head trauma presented after 6 hours having size of hematoma above 30 ml (as per axial images of CT brain) were included. Frequency of favorable and unfavorable outcomes were noted after three months of follow-up. Outcome was termed as favorable if patient had good recover or moderate disability. Results: Out of total 119 patients, 89 (74.8%) were male. Unfavorable outcome was noted in 37.8% (n=45) of total patients with delayed presentation to the hospital, while favorable outcome was noted in 62.2% (n=74) of patients. Good recovery and moderate disability were observed in 27.7% (n=31) and 34.5% (n=41) of total patients respectively. While, severe disability and vegetative state was recorded in 26.1% (n=31) and 7.6% (n=9) of patients respectively. Practical Implications: Efforts should be made to increase awareness about timely presentation and interventions for better surgical outcomes among patients of extradural hematoma. Conclusion: Frequency of unfavorable surgical outcome of extradural hematoma found to be 37.8% in head trauma patients with late presentation. Keywords: Extradural Hematoma, Glasgow Coma scale, surgical outcome
Frequency of Anemia among the Patients Presented with Myocardial Infarction at a Tertiary Care Hospital of Karachi, Pakistan
Authors: Lal Chand Farhan Memon , Ahmed Rameez , Ali Aijaz , Mal Vashu , Memon Ghulam Rasool
Published: December 2022

Objective: To determine the frequency of anemia among the patients presented with myocardial infarction (MI) at a tertiary care hospital of Karachi, Pakistan. Study Design: A cross-sectional study. Place and Duration: Adult Cardiology Department of National Institute of Cardiovascular Disease (NICVD), Karachi from February 2022 to July 2022. Methodology: A total of 253 patients diagnosed with MI were included. Demographic and clinical characteristics of the patients were recorded. Hemoglobin level was obtained at the time of admission. Results: In a total of 253 patients, the mean age was 54.36±8.21 years. There were 187 (73.9%) male and 66 (26.1%) female. Frequency of anemia among the patients presented with myocardial infarction was found to be in 72 (28.5%). Frequency of anemia among patients presenting with MI was noted. Practical Implications: Anemia in myocardial infarction patients has affected the patency of vessel so this single most essentially and easily treatable component should be corrected in these patients.. Conclusion: High prevalence of anemia in patients presenting with MI was noted. Keywords: Anemia, hemoglobin, ischemic heart disease, myocardial infarction
Aggression Assessment and Plasma Serotonin Level amongst Pakistani Youngsters
Authors: Riffat Sumaira , Zahid Sahar , Hussain Mushtaq , Rehman Raza Ur , Qureshi Masood Anwar
Published: December 2022

Background: Aggressive behavior is a multifaceted construct involving various physiological modulators and genetic factors with a variable frequency in different populations. Of multiple genetic factors, serotonin is known to have profound role with disagreement exists in relation to its expressional alignment with the intensity of aggression. The existing study is designed to develop alignment of the psychological scale of aggression with the plasma serotonin levels. Methodology: Buss Perry Aggression Questionnaires (BP-AQs) were distributed among male and female students of different universities of Karachi. Among those, 2000 properly filled questionnaires were selected to be scrutinized and scored which led to selection of 80 students each of score lower than 60 (least aggressive individuals) or higher than 100 (most aggressive individuals). Plasma serotonin levels of the 160 individuals were then measured by ELISA. Results: Cumulatively, males tend to have higher BP-AQ score than females (79.14+16.22 vs. 75.28+16.97) and also in physical aggression (23.81+6.44 vs. 21.05+6.17) statistically significant difference of p=0.0011 and p<0.0001, respectively. All scores of different forms of aggression were found positively correlated with each other and with strong statistical significance. Level of serotonin was found significantly higher (p=0.0004) in females (244ng/ml) compared to males (70.39ng/ml). Plasma serotonin levels were negatively correlated with BP-AQ scores especially in females (p=0.0222) and in whole of the assessed subjects (p=0.0069). Practical implication: In order to facilitate a better understanding of aggressive behaviour, this study helps to align a physiological biomarker with psychological tools. Additionally, serotonin can be used as a biomarker to comprehend the physiological underpinnings of aggression, and future studies can be planned that use serotonin or its receptors in relation to aggressive behaviour. And it will positively impact the mental health of any society. Conclusion: The findings in total suggest male holds more aggressive behavior especially physical aggression compared to females. Additionally, the aggression in female is more profoundly associated with the low plasma serotonin level. Keywords: Aggression, Behavior, Hostility, Adolescents, Neurotransmitters, Serotonin,
Diagnostic Laparoscopy and its Role in Patients with Chronic Abdominal Pain: Study from a Tertiary Care Hospital
Authors: Sami Farrukh , , Aslam Muhammad , Ali Muhammad Tahir , Hashmi Javaid Sajjad , Khan Muhammad Tariq , Memon Muhammad Hanif
Published: December 2022

Objective: To find the efficacy of diagnostic laparoscopy and its role in patients with chronic abdominal pain. Study Design: Observational study Place and Duration of Study: Department of General Surgery, Ali Fatima Hospital/Abu Umara Medical & Dental College Lahore from 1st July 2021 to 31st March 2022. Methodology: Seventy patients suffering from chronic abdominal pain were enrolled. An informed written consent was taken from each of them as an approval of participation. The age of the patients was between 20-65 years. Mostly the left side of the abdomen upper-quadrant was opted. Post creation of pneumo-peritoneum a 3 trocar technique which is standardized procedure was applied and a 10mm port through umbilical while two lateral trocars of 5 mm were used. The completed abdominal-cavity was investigated in detail initializing from the liver then gall bladder as well as anterior-surface of stomach and also the spleen. In women uterus as well as Douglas pouch was examined in context to fluid consistency, colour in addition to its site. The specimens were collected and sent to the histopathological lab for analysis. Results: The mean age of the patients was 36±15.3 years with majority were males with 55.71%. Around 45.71% patient’s pain site was at the right lower quadrant while 21.42% had left lower quadrant. The outcomes of laparoscopic investigation showed 27.10% patients to have appendix related pathology, while 19% had bands of adhesion. Conclusion: Laparoscopic proved to be an effective surgical technique in evaluating exact causes of chronic abdominal pain especially in cases where traditional methods have failed to explain the particular cause. Keywords: Bowel movement, Laparoscopy, Recurrent, Prolonged, Well-being
ROMANIA AS A BROTHER-IN-ARMS THROUGH FINNISH EYES IN WORLD WAR II
Authors: ALENIUS Kari
Published: December 2022

Very little has been relatively studied about the interaction between Finland and Romania. Most existing studies deal with the interwar period and World War II, but there is still room for complementary interpretations. This study focuses on Finns’ perceptions of Romania, especially from the perspective of brotherhood in arms between the two countries. The theme is worth exploring because during the Second World War, both Finland and Romania considered the development of mutual relations more important than ever before. This study is based on an extensive number of original sources. The analysis shows that there were different attitudes towards Romania as a brother-in-arms, but the attitude was positive in principle. The differences are explained by the type of goals set for the future development of the relationship between Finland and Romania. It is evident that Romania was valued as a brother-in-arms by a wide range of citizens. The Finnish media and the NGOs behind it conveyed a positive image of Romania, and emphasized the common interests of Finland and Romania in the ongoing war. However, the Finnish leadership was cautious about developing bilateral relations, as it considered it necessary to strike a balance between Germany and the Western powers. The brotherhood of arms was therefore not allowed to become too close.
O USO RACIONAL DA TOXINA BOTULÍNICA E DO ÁCIDO HIALURÔNICO: REVISÃO DE LITERATURA
Authors: Yamasaki Milena Yumi , Da Silva Alice Maria , Ferreira de Lima Matheus , Da Graça Fagundes Ana Carolina , Tognetti Valdinéia Maria
Published: December 2022

A odontologia tem abordado em suas literaturas a importância de se preocupar com a saúde associada à autoestima do paciente, evidenciando os problemas como um todo e não apenas como casos clínicos isolados, sendo comprovado que a aparência física possui influência significativa em vários conceitos da vida do indivíduo. Nessa perspectiva, enfatiza-se a busca cada vez mais frequente de procedimentos estéticos, como a toxina botulínica e o ácido hialurônico com o intuito de alcançar os resultados desejados, com maior facilidade e por meio de procedimentos menos invasivos que alcancem o desejo e a necessidade do paciente. O objetivo foi realizar uma revisão de literatura que possa abordar de forma ampla a capacidade de atuação do cirurgião dentista dentro do contexto da estética, com o uso de preenchedores, pontuando também as principais indicações e os efeitos adversos a fim de buscar a segurança em cada procedimento. Contudo, é um assunto novo no meio da odontologia, e para que se tenha sucesso, é necessário o preparo do profissional para a atuação na área.
PENGARUH KOMPETENSI AKUNTANSI KEUANGAN DAN PENGALAMAN PRAKERIN TERHADAP KESIAPAN KERJA SISWA KELAS XII AK SMKN 1 REJOTANGAN TAHUN AJARAN 2020/2021
Authors: Istikomah Hilda , Subiyantoro Hari
Published: December 2022

ABSTRAK

Kesiapan kerja akan terbentuk apabila faktor-faktor dari kesiapan kerja terpenuhi, beberapa faktor diantaranya ialah kompetensi akuntansi dan juga pengalaman prakerin. Rumusan masalah pada penelitian ini ialah “Adakah Pengaruh antara variabel Kompetensi Akuntansi Keuangan (X1) dan Pengalaman Prakerin (X2) terhadap Kesiapan Kerja (Y). Metode pengumpulan data ialah angket dan dokumentasi. Dokumentasi dilakukan untuk pengumpulan data variabel (X1) dan (X2). Instrumen angket digunakan untuk pengumpulan data (Y) dengan penskoran sangat setuju(SS), setuju (S), tidak setuju (TS), sangat tidak setuju (STS). Sampel penelitian yang digunakan ialah 72 siswa dengan menggunakan teknik random sampling. Untuk mengetahui pengaruh antara variabel X1, X2 dan Y menggunakan analisis regresi berganda. Dari hasil analisis data bahwa Fhitung 251,430 > F tabel 3,13, dengan demikian H0 ditolak dan Ha diterima. Berdasarkan hasil uji koefisiensi determinasi mendapatkan nilai sebesar 0,879, artinya secara simultan pengaruh X1 dan X2 terhadap Y sebesar 87,9%. Dapat disimpulkan bahwa “Terdapat Pengaruh yang Signifikan antara Kompetensi Akuntansi Keuangan dan Pengalaman Prakerin terhadap Kesiapan Kerja Siswa Kelas XII AK SMKN 1 Rejotangan Tulungagung Tahun Ajaran 2021/2022. Hasil penelitian ini dapat digunakan sebagai referensi untuk memperbaiki kebijakan maupun progam-progam yang berkaitan dengan kesiapan kerja siswa.

Kata Kunci : Kompetensi Akuntansi, Prakerin, Kesiapan Kerja.

 

ABSTRACT

Work readiness will be formed if the factors of job readiness are met, several factors including accounting competence and internship experience. The formulation of the problem in this study is "Is there any influence between the variables of Financial Accounting Competence (X1) and Prakerin Experience (X2) on Work Readiness (Y). Data collection methods are questionnaires and documentation. Documentation was carried out for data collection on variables (X1) and (X2). The questionnaire instrument was used for data collection (Y) with a score of strongly agree (SS), agree (S), disagree (TS), strongly disagree (STS). The research sample used was 72 students using random sampling technique. To determine the effect of variables X1, X2 and Y using multiple regression analysis. From the results of data analysis that Fcount 251.430 > F table 3.13, thus H0 is rejected and Ha is accepted. Based on the results of the coefficient of determination test, the value is 0.879, meaning that the simultaneous effect of X1 and X2 on Y is 87.9%. It can be concluded that “There is a Significant Influence between Financial Accounting Competence and Prakerin Experience on Work Readiness of Class XII AK Students at SMKN 1 Rejotangan Tulungagung for the Academic Year 2021/2022. The results of this study can be used as a reference to improve policies and programs related to student work readiness.

Keywords : Accounting Competence, Industrial Work Practices, Job Readiness
Pengaruh Literasi Keuangan Dan Disiplin Kerja Terhadap Kinerja Pekerja Industri Meubel Di Desa Touliang Oki
Authors: Maerah Tivany , Korompis Consuslasia , Dame Joubert M.
Published: December 2022

This study aims to determine the extent of the influence of financial literacy and work discipline on the performance of furniture industry workers in the village of Touliang Oki. The method used in this study uses a type of quantitative research survey method. The population in this study was 51 and the research sample was 45. Based on data analysis The results showed that financial literacy has a positive or significant effect on employee performance. Thus, the first hypothesis is accepted. The results showed that work discipline has a positive or significant effect on employee performance. Thus, the second hypothesis is accepted. The results showed that Financial Literacy and Work Discipline had a positive or significant effect together on employee performance. Thus, the third hypothesis is accepted.
Pengaruh Kapasitas Produksi Dan Permintaan Terhadap Pendapatan Petani Gula Aren Di Desa Tombatu 2
Authors: Dopas Farly , Korompis Consuslasia , Tawas Yance
Published: December 2022

Penelitian ini bertujuan untuk mengetahui Pengaruh Kapasitas Produksi Dan Permintaan Terhadap Pendapatan Petani Gula Aren Di Desa Tombatu 2. Metode penelitian yang digunakan penulis adalah metode survey pendekatan kuantitatif. populasi dalam penelitian ini berjumlah 33 orang dengan sampel 30 orang. Berdasarkan hasil dari analisis dan pembahasan yang dilakukan dengan menggunakan regresi linier berganda, dapat ditarik kesimpulan sebagai berikut: Hasil penelitian menunjukkan bahwa Kapasitas Produksi (X1) memiliki pengaruh positif atau signifikan terhadap Pendapatan Petani Gula Aren (Y). Dengan demikian, hipotesis pertama diterima. Hasil penelitian menunjukkan bahwa Permintaan (X2) memiliki pengaruh positif atau signifikan terhadapPendapatan Petani Gula Aren (Y). Dengan demikian, hipotesis kedua diterima. Hasil penelitian menunjukkan bahwa Kapasitas Produksi (X1) dan Permintaan (X2) memiliki pengaruh positif atau signifikan secara bersama-sama terhadap Pendapatan Petani Gula Aren (Y). Dengan demikian, hipotesis ketiga diterima.
Kata Kunci: Kapasitas produksi, permintaan dan pendapatan petani
 
 
This study aims to determine the effect of production capacity and demand on palm sugar farmers' income in Tombatu Village 2. The research method used by the author is a survey method with a quantitative approach. population in this study amounted to 33 people with a sample of 30 people. Based on the results of the analysis and discussion conducted using multiple linear regression, the following conclusions can be drawn: The results show that Production Capacity (X1) has a positive or significant effect on Palm Sugar Farmers' Income (Y). Thus, the first hypothesis is accepted. The results showed that demand (X2) had a positive or significant effect on the income of palm sugar farmers (Y). Thus, the second hypothesis is accepted. The results showed that Production Capacity (X1) and Demand (X2) had a positive or significant effect together on Palm Sugar Farmers' Income (Y). Thus, the third hypothesis is accepted.
Keywords: Production capacity, farmer demand and income
PENGARUH MOTIVASI ORANG TUA DAN FASILITAS BELAJAR TERHADAP MINAT BELAJAR SISWA SMA NEGERI 1 ERIS
Authors: Mantiri Jesika , Dame Joubert M. , Ranti Devyano
Published: December 2022

ABSTRAK

Penelitian ini bertujuan untuk mengetahui pengaruh motivasi orang tua dan fasilitas belajar terhadap minat belajar siswa di kelas X IPS SMA Negeri 1 Eris. Metode penelitian ini adalah metode survey dengan sampel 65 orang. Teknik yang digunakan dalam pengumpulan data adalah teknik kuisioner (angket) . Hasil penelitian dianalisis dengan metode analisis regresi linier ganda, analisis korelasi sederhana dan analisis korelasi ganda.Adapun hasil dari penelitian ini menunjukan. Terdapat pengaruh yang signifikan antara motivasi orang tua dengan minat belajar siswa di kelas X Ips SMA Negeri 1 Eris. Terdapat pengaruh yang signifikan antara fasilitas belajar dengan minat belajar siswa di kelas X Ips SMA Negeri 1 Eris.Terdapat pengaruh yang signifikan antara Motivasi orang tua dan minat belajar siswa terhadap kemampuan belajar siswa di kelas X Ips SMA Negeri 1 Eris.
PENGARUH ORIENTASI BELANJA DAN PENGALAMAN PEMBELIAN TERHADAP MINAT BELI SECARA ONLINE DI KELURAHAN INOBONTO 1
Authors: Mokodompit Sriditia , Korompis Consuslasia , Ranti Deviano
Published: December 2022

ABSTRAK

Penelitian ini bertujuan untuk mengetahui pengaruh orientasi belanja dan pengalaman pembelian terhadap minat beli secara online di Kelurahan Inobonto 1. Metode penelitian ini adalah metode jenuh dengan sampel 45  orang. Teknik yang digunakan dalam pengumpulan data adalah teknik kuisioner (angket) dan dokumentasi. Hasil penelitian dianalisis dengan metode analisis regresi linier ganda, analisis korelasi sederhana dan analisis korelasi ganda. Adapun hasil dari penelitian ini menunjukan : (1) Orientasi Belanja berpengaruh positif dan signifikan terhadap Minat Beli Secara Online di Kelurahan Inobonto 1 dengan jumlah thitung > ttabel = 7,47 > 1,66 (2) Pengalaman Pembelian berpengaruh positif dan signifikan terhadap Minat Beli Secara Online di Kelurahan Inobonto dengan jumlah thitung > ttabel = 8,12 > 1,66 (3) Oreintasi belanja dan Pengalaman Pembelian berpengaruh positif dan signifikan terhadap Minat Beli Secara Online sebesar 36,01% dengan jumlah fhitung 11,11 > ftabel =  > 3,22.Kata Kunci : Orientasi Belanja, Pengalaman Pembelian , Minat Beli Secara Online.

 

 ABSTRACT 

This study aims to determine the effect of shopping orientation and purchasing experience on online buying interest in Inobonto 1. This research method is a saturated method with a sample of 45 people. The technique used in data collection is a questionnaire (questionnaire) and documentation technique. The results of the study were analyzed using multiple linear regression analysis, simple correlation analysis and multiple correlation analysis. The results of this study indicate: (1) Shopping orientation has a positive and significant effect on Online Purchase Intention in Inobonto 1 Village with a total of tcount > ttable = 7.47 > 1.66 (2) Purchase Experience has a positive and significant effect on Purchase Intention Online in Inobonto Village with the number of tcount > ttable = 8.12 > 1.66 (3) Shopping orientation and Purchase Experience have a positive and significant effect on Online Purchase Interest of 36.01% with fcount 11.11 > ftable = > 3.22.

Keywords: Shopping Orientation,Buying Experience,Online Buying Interest.
PENGEMBANGAN MEDIA PEMBELAJARAN POWER POINT MELALUI MATERI KEARSIPAN UNTUK MENINGKATKAN MINAT BELAJAR SISWA DI SMK NEGERI 9 MANADO
Authors: Silalahi Elisa , Tawas Yance , Lempas Jety
Published: December 2022

ABSTRAK

Penelitian ini bertujuan untuk Mengembangkan Media Pembelajaran Power Point Melalui Materi Kearsipan Untuk Meningkatkan Minat Belajar Siswa. Penelitian ini adalah penelotian pengembangan dengan menggunakan model ADDIE (Analysis, Design, Development or Production, Implementation or Delivery and Evaluations). Teknik pengumpulan data pada penelitian ini menggunakan Angket Validasi (validasi ahli media dan validasi ahli materi) dan angket respon siswa. Hasil dari angket validasi ahli materi termasuk dalam kriteria “sangat layak” dengan presentase 93,3%, hasil dari angket validasi ahli media termasuk dalam kriteria “sangat layak” dengan presentase 78%. Media Pembelajaran dinyatakan sangat layak digunakan dalam proses pembelajaran.

Kata Kunci : Power Point, Media Pembelajaran, Arsip

 

 

 

 

ABSTRACT

This study aims to develop Power Point learning media through archival materials to increase student interest in learning. This research is a development research using the ADDIE model (Analysis, Design, Development or Production, Implementation or Delivery and Evaluations). The data collection technique in this study used a Validation Questionnaire (validation of media experts and validation of material experts) and student response questionnaires. The results of the material expert validation questionnaire are included in the "very feasible" criteria with a percentage of 93.3%, the results from the media expert validation questionnaire are included in the "very feasible" criteria with a percentage of 78%. Learning Media is declared very suitable to be used in the learning process.

Keywords: Power Point, Learning Media, Archives
Precios petroleros fijados por la OPEP (1973) y epistemología económica poppereana
Authors: Maldonado Fabio
Published: December 2022

La fijación unilateral de los precios de referencia fiscal por parte de seis países miembros de la OPEP el 17 de octubre de 1973 fue uno de los acontecimientos económicos más cruciales en la historia petrolera y económica internacional. La teoría económica se vio obligada a concebir un constructo inédito como el de estanflación como representación conceptual del hecho económico (también inédito) de inflación acompañada por desempleo. Aquí se examinan dos interpretaciones rivales sobre ese acontecimiento y se explican los aciertos y desaciertos de los contenidos lógicos de dos teorías rivales (la microeconómica y de la de teoría de la renta) desde la epistemología poppereana.
PUBLIC SPEAKING FOR STUDENT SEBAGAI UPAYA PENINGAKATAN KEMAMPUAN KOMUNIKASI SISWA SMA NEGERI 1 TINAMBUNG
Authors: Rahmaniah Nurhafida , AR Rezki Amaliyah
Published: December 2022

Manusia sebagai makhluk social perlu untuk berinteraksi satu dengan lainnya. Interaksi dapat dilakukan dengan cara saling berkomunikasi. Namun jika kemampuan komunikasi kurang, maka interaksi sosial juga akan berkurang. Oleh karena itu, sejak dibangku sekolah, siswa siswi perlu dilatih kemampuan komunikasi melaui kegiatan public speaking. Adapun bentuk kegiatan yaitu pelatihan “public speaking for student” yang diikuti oleh 20 peserta siswa siswi SMA Negeri 1 Tinambung. Hasil yang diperoleh setelah kegiatan terlaksana yaitu kegiatan ini mampu meningkatkan kemampuan komunikasi siswa, kepercayaan diri dalam berbicara dan kelancaran menanggapi pendapat. Selain itu pengetahuan siswa tentang pentingnya kemampuan public speaking juga meningkat.
AKSI BERSIH-BERSIH WILAYAH PESISIR PANTAI “MEMBANGUN GENERASI MILENIAL SADAR TERHADAP LINGKUNGAN YANG SEHAT DAN BERSIH”
Authors: Tikirik Wita Oileri , Sahrianti Nini , Nur Akbar , Swarjana I Kadek Dwi , Hijrah Ince
Published: December 2022

Dalam kegiatan pengabdian kepada masyarakat ini, BEM dan Satuan Inovasi Riset dan Pengabdian Masyarakat telah melakukan koordinasi kepada pihak terkait agar kegiatan ini dapat terlaksana sesuai dengan jadwal dan waktu yang telah ditetapkan. Setelah mendapat izin dari WK-III dan WK-I dan Ketua STIKES Andini Persada maka Satuan Inovasi Riset telah memberikan penyampaian agar kegiatan Pengabdian Kepada Masyarakat disosialisasikan kepada seluruh Pengurus BEM STIKES Andini Persada agar pihak pengurus BEM yang menyampaikan ke seluruh mahasiswa STIKES Andini Persada Mamuju. Kegiatan pengabdian kepada masyarakat ini merupakan kerjasama BEM dengan STIKES Andini Persada melalui Satuan Inovasi dan Pengabdian Masyarakat. Dalam kegiatan ini telah mensosialisasikan terlebih dahulu dilingkungan civitas akademika dan mahasiswa melalui BEM dan berkoordinasi dengan WK-III  bagian kemahasiswaan STIKES Andini persada agar memberi peluang dan ruang kepada seluruh dosen dan mahasiswa untuk ikut terlibat dan berpartisipasi dalam mendukung kegiatan pengabdian kepada masyarakat dengan Aksi Bersih-Bersih Wilayah Pesisir Pantai dengan tema “Membangun Generasi Milenial Sadar Terhadap Lingkungan yang Sehat dan Bersih” sebelum melaksanakan pengabdian kepada masyarakat seluruh dosen dan mahasiswa yang ikut dalam kegiatan pengabdian kepada masyarakat melakukan senam bersama di Halaman Kampus STIKes Andini Persada. Hal ini dilakukan agar tetap dapat tetap menjaga kesehatan melalui senam aerobik dan membangun kebersamaan sebelum melaksanakan kegiatan.