bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 15 from Molecular Pathways and Cellular Subsets Associated with Adverse Clinical Outcomes in Overlapping Immune-Related Myocarditis and Myositis
Authors: Siddiqui Bilal A. , Palaskas Nicolas L. , Basu Sreyashi , Dai Yibo , He Zhong , Yadav Shalini S. , Allison James P. , Sheth Rahul A. , Tummala Sudhakar , Buja Maximilian , Bhattacharjee Meenakshi B. , Iliescu Cezar , Rawther-Karedath Anishia , Deswal Anita , Wang Linghua , Sharma Padmanee , Subudhi Sumit K.
Published: August 2024

Cell-cell communication analysis from myeloid cells and cytotoxic T cells to fibroblasts in myocarditis
Supplementary Figure 12 from Molecular Pathways and Cellular Subsets Associated with Adverse Clinical Outcomes in Overlapping Immune-Related Myocarditis and Myositis
Authors: Siddiqui Bilal A. , Palaskas Nicolas L. , Basu Sreyashi , Dai Yibo , He Zhong , Yadav Shalini S. , Allison James P. , Sheth Rahul A. , Tummala Sudhakar , Buja Maximilian , Bhattacharjee Meenakshi B. , Iliescu Cezar , Rawther-Karedath Anishia , Deswal Anita , Wang Linghua , Sharma Padmanee , Subudhi Sumit K.
Published: August 2024

Differentially expressed genes (DEGs) in IL1B+ Myeloid cell subsets and association of frequency of cytotoxic CD8+ T cells with clinical outcomes
Figure 3 from FLT3/CD99 Bispecific Antibody–Based Nanoparticles for Acute Myeloid Leukemia
Authors: Ali Atham , Phan Alvin , Vaikari Vijaya , Park Mincheol , Pospiech Mateusz , Chu Ryan , Meng Yiting , MacKay John A. , Alachkar Houda
Published: August 2024

Both antibody fusions exhibit binding and specificity in MV4-11 and U937 cells. A, CD99-A192 (Rhodamine) and FLT3-A192 (FITC) bound to MV4-11 AML cells (FLT3-ITD+/CD99+). B and C, In a competitive binding assay using U937 cells (FLT3−/CD99+), we treated U937 cells with all three of our fusion proteins followed by incubation with a FITC conjugated CD99 commercial antibody (cAb) and measured CD99 cAb FITC signal using flow cytometry. We observed inhibition within both the CD99-A192 and Co-Assembled-treated groups compared with the control group.
CARBON SEQUESTRATION FOR AGROSILVICULTURE AGROFORESTRY PRACTICES: PRELIMINARY RESULTS FROM THREE INVESTIGATED VILLAGES IN UTTARADIT PROVINCE, NORTHERN, THAILAND
Authors: Podong Chattanong , Khamfong Krissana , Noinamsai Supawadee , Mhon-ing Sukanya
Published: August 2024

ARTICLE HIGLIGHTS- Agroforestry boosts carbon storage, reducing greenhouse gas emissions significantly.- Diverse tree-based farming enhances biodiversity, soil health, and climate resilience.- Carbon sequestration in agroforestry supports sustainable agriculture and environmental balance.- Agroforestry practices mitigate climate change by storing carbon in trees and soil.- Combining trees with crops provides multiple ecological and economic benefits.ABSTRACTOne of the processes for compensating greenhouse gas emissions is atmospheric carbon removal and storage in the terrestrial biosphere. Agricultural systems to which trees are returned for careful management alongside crops and animals are thought to be substantial CO2 sinks. People are increasingly realizing the importance of agroforestry because it is good for the environment and farming. In this study, total carbon pools from the aboveground biomass carbon (ABGC), forest floor carbon (FFC), and soil organic carbon (SOC) were investigated and carbon storage data for some agroforestry practices native to Uttaradit in northern Thailand were analyzed. The role of these carbon pools in reducing CO2 concentrations in the atmosphere was also discussed. The results showed differences in the total carbon stock sourced from traditional agroforestry (TAF), applied agroforestry (AAF), and developed agroforestry (DAF). The total carbon store (ABGC + TFFC + SOC) of TAF, AAF, and DAF was 267.05 Mg C/ha, 226.48 Mg C/ha, and 324.70 Mg C/ha, respectively. SOC contributed 47.64%, 54.26%, and 44.81% and ABGC contributed 22.75%, 19.79%, and 23.90% to the total carbon stock in TAF, AAF, and DAF, respectively. The CO2 adsorption was 979.27 Mg CO2/ha, 830.50 Mg CO2/ha, and 1,190.6 Mg CO2/ha in TAF, AAF, and DAF, respectively. It is clear that agroforestry systems serve as carbon sinks in terrestrial ecosystems. Although the comparison of agroforestry practices and other land use types is important for carbon mitigation and the implementation of the “Land Use, Land Use Change, and Forestry” concept for CO2 sinks, it is also crucial to compare the potential of carbon sequestration in different CO2 pools.
ENDEMISM AND CONSERVATION STATUS OF TREE SPECIES OF FRESHWATER SWAMP FOREST, PERAK TENGAH, MALAYSIA
Authors: Nawi Liliwirianis , Suratman Mohd Nazip , Yusof Farida Zuraina Mohd , Mohamad Abdul Latiff
Published: August 2024

ARTICLE HIGHLIGHTS- Approximately 3,364 tree individuals with a diameter at breast height (dbh) of 10.0 cm and above were assessed in the Perak Tengah freshwater swamp forest. - The study has recognised 58 species identified are new to Perak.- 72 tree species are listed as endemic, and 194 species are listed in the Red List of Threatened Species by The International Union for Conservation of Nature (IUCN).- This study mphasize the need to preserve ecology and mitigate threats.
ABSTRACTThe forests of Peninsular Malaysia have long been recognized as a significant home of endemic species. The purpose of this study was to assess the endemism and conservation status of tree species present in the Perak Tengah freshwater swamp forest. A total of 150 plots (20 m × 20 m) were established in the study area using a random sampling design. Approximately 3,364 tree individuals with diameter at breast height (dbh) of 10.0 cm and above were enumerated in all plots. In the study area, 58 species identified are new to Perak, 72 tree species are listed as endemic, and 194 species are listed in the Red List of Threatened Species by IUCN. Thus, it is crucial to preserve the ecology and lessen the impact of threats in the Perak Tengah freshwater swamp forest, which is home to numerous endemic and endangered species.
COMPOSITION, STRUCTURE, AND CARBON SEQUESTRATION OF DIFFERENT RAINFOREST ECOSYSTEMS IN THE GUNUNG GEDE PANGRANGO NATIONAL PARK, INDONESIA
Authors: Sunyata Agus , Rakhmi Zulhida Isna , Triwahyuningsih Nike , Raharja Kanda
Published: August 2024

ARTICLE HIGLIGHTS- High demand for environmental services makes the park vulnerable to human activities.- Both ecosystems are well regenerated; seedling > sapling > pole > tree (inverted J)- Both ecosystems show normal diversity conditions and stable species distribution.- Growth of Maesopsis eminii needs monitoring to preserve forest purity.- Montane forests have greater biomass, carbon stocks, less anthropogenic disturbanceABSTRACTThe Gunung Gede Pangrango National Park (GGPNP) area is one of the vital ecosystems that support the environment in West Java Province, Indonesia. It is a unique area that has multiple forest ecosystems, including lowland rainforest and montane rainforest ecosystems. Despite the GGPNP’s status as a conservation area, the high demand for the GGPNP’s environmental services makes the region vulnerable to disturbances from human activities. Several studies have been conducted in the GGPNP area (lowland and montane forest ecosystems), however, the results of this study are still necessary to explain the forest dynamics and forest carbon sequestration in this location. The objective of this research was to analyze the structure, composition, and carbon sequestration of stands in the lowland and montane rainforest ecosystems in the GGPNP area. Data processing and analyses were conducted using diversity indices, biomass-carbon stock estimation, and carbon dioxide sequestration estimation. The results showed that the GGPNP lowland and montane rainforest ecosystems were well regenerated. The number of seedlings > saplings > poles > trees and the graph showed a reverse “J” pattern. The GGPNP lowland rainforest ecosystem was dominated by Neonauclea lanceolata and had relatively higher species diversity. The GGPNP montane rainforest ecosystem was dominated by Castanopsis acuminatissima with a higher individual density, denser canopy, and more complex canopy strata. The lack of regeneration in several species of trees heightens the threat to these species’ existence in the future. Biomass, carbon stocks, and carbon sequestration in the GGPNP montane rainforest were greater than those in the GGPNP lowland rainforest. The GGPNP montane rainforest ecosystem had older forest stands, a larger average tree diameter, and lower potential for anthropogenic disturbances.
DISTRIBUTION OF THE THALLOID LIVERWORT GENUS MARCHANTIA (MARCHANTIACEAE) IN NORTH SUMATRA, INDONESIA
Authors: Siregar Etti Sartina , Pasaribu Nursahara , Sofyan Muhammad Zaidun
Published: August 2024

ARTICLE HIGLIGHTS- The survey method was successful in identifying the species Marchantia and mapping their distribution in North Sumatra- Eight taxa of Marchantia confirmed in North Sumatra, M. emarginata subsp. cuneiloba has the most widely distributed species. - Species distribution linked to environmental factors like elevation, humidity, rainfall, soil types, slope, solar intensity, and types of land coverABSTRACTMarchantia is one of the large genus complex thalloid liverworts (Marchantiophyta). The species of Marchantia has a wide distribution throughout the world, and occupies a variety of substrates. Studies on the presence and distribution of Marchantia species are still limited in North Sumatra. Therefore, the research was carried out to inventory the species of Marchantia and map their distribution in North Sumatra. Survey method was used to inventory the species of Marchantia, covering 9 locations, namely: Aek Nauli Forest, Bukit Barisan National Forest Park, Bukit Lawang, Resort Cinta Raja, Dolok Tinggi Raja Nature Reserve, Sibayak Mountain, Sicike-cike Natural Park, Silima-lima waterfall, and Taman Eden 100 Natural Park.  Geographic Information System (GIS) was used to map the distribution of the species. The results showed that there were eight taxa of Marchantia confirmed in North Sumatra, namely, M. acaulis, M. emarginata subsp. emarginata, M. emarginata subsp. cuneiloba, M. geminata, M. paleacea subsp. paleacea, M. polymorpha, M. treubii, and Marchantia sp. The most widely distributed species of Marchantia is M. emarginata subsp. cuneiloba, found in 7 study locations. Species with the least distribution are M. treubii and Marchantia sp., each species found only in one location. Marchantia spp. in North Sumatra spread at an altitude of 77 to 1976 m alt, occupying habitats with 6 types of soil (orthic acrisol, humic andosol, humic acrisol, and humic cambisol), with rainfall of 1800-3600 mm/year. Marchantia species are found on sloping plains to steep, in various habitat, namely secondary forest, primary and secondary forest borders, dryland farming, primary and plantation borders, and plantations. The results of this study are important for the conservation of Marchantia spp. in North Sumatra considering the many benefits of the species.
Suspecting Change in Cameroon: Slums Improvement and the Logics of Belonging in Yaoundé
Authors: Belinga Ondoua Patrick Dieudonné
Published: August 2024

Based on an ethnographic storytelling research, this article analyses the tensions surrounding the land tenure measures of the Participatory Slum Upgrading Programme (PSUP) in a slum of Yaoundé. The aim of the programme was to make sure that the property owners residing near roads and those in swampy areas renovate their houses failure to which would make them rent the newly renovated houses ‘of their own’ by PSUP. The article shows that this measure failed, not because of the failure of the government or the intrinsic opposition of the inhabitants to change, but because the PSUP indirectly attacked the land relations and the logics of belonging. This led to latent tensions in the form of suspicious relations between ‘autochthons’ and ‘allogenic’ inhabitants, suspecting each other of ‘malicious’ intentions. This economy of suspicion spreads by attacking the state promoters of the PSUP who were accused of plotting an invasion of the area for the benefit of specific groups and communities. The aim of this paper is therefore twofold. On the one hand, against the idealistic trend that insists on the peaceful nature of development mechanisms, it shows that conflicts are inherent in any process of social change. On the other hand, contrary to studies that consider land and inter-ethnic conflicts as essentially marked by brutal and physical violence, it shows that there are forms of insidious violence that accompany the processes of change in land regularisation.
Collecting Multi-Actor Family Network Data
Authors: de Bel Vera , van Duijn Marijtje A.J.
Published: August 2024

Although ‘the family’ is arguably the most fundamental of all social networks, surprisingly little data are available that enable researchers to study the full web of relationships between family members. Mapping family relationships from multiple – preferably ‘all’ – family members’ perspectives enables understanding relational dependencies, such as how parental divorce reverberates through the network. This article introduces a multi-actor family network survey method aimed at collecting ‘complete’ family network data. It discusses the design and implementation of the Lifelines Family Ties project. In this data collection project, a total of 160 children, parents, grandparents, aunts, uncles, and stepfamily members reported on their current and past well-being and their family relationships (contact, support, affection) with 524 family members, resulting in a dataset covering nearly 900 relationships. The article concludes by providing a preview of possible analysis techniques for future users of the Lifelines Family Ties dataset or other future multi-actor family network data.
Memory, Materials and the Built Environment
Authors: Leworthy Paul
Published: August 2024

This essay rethinks the interrelation between materials and memory, asking: how do our encounters with materials in the built environment confront us with the past and what is the role of memory in such encounters? It argues that encounters with building materials constitute confrontations with the past, as we observe pastness in the built environment, instinctively undertake relative dating, and, as a result, temporally locate ourselves in relation to the space and the space in relation to ourselves. Integrating a key strand of architectural theory – attention to building materials and the material environment – into memory studies, the essay also proposes that the meanings of building materials are mediated by memory and that building materials themselves mediate (cultural) memory. By focusing on materials rather than events or architectural styles, it exposes the multiple and multifaceted cultural memory processes inherent in our everyday engagement with materials.
Memory In the “Magic City”
Authors: Bond Lucy , Rapson Jessica
Published: August 2024

This article explores the naturalisation of memories of racial violence at heritage sites in and around Birmingham, Alabama. Birmingham’s cityscape has been forged from systemic processes of racial capitalism that have led to ongoing forms of environmental racism. Against this backdrop, prominent tourist attractions prioritise the celebration of industrial heritage above acknowledging past and present forms of racialised injustice – from slavery to convict leasing, segregation to redlining. These sites present a sanitised account of the city’s iron and steel industry, resulting in a selective transmission and production of memories of industrial progress which obscures the operations of racial capitalism and the environmental racism it produces. This heritage, we suggest, cannot reconcile the brutality of inequitable labour systems, such as convict leasing, and the environmental violence of industrial production with the celebration of capitalist progress that positions Birmingham as the “Magic City” of industrial miracles.
New species of Salicaceae with opposite leaves from the Atlantic Forest, Brazil
Authors: NEPOMUCENO ÁLVARO , DOMÍNGUEZ YOANNIS , NEGRÃO RAQUEL , AMARAL RENARA NICHIO , DUTRA VALQUÍRIA FERREIRA , ALVES-ARAÚJO ANDERSON
Published: August 2024

Abatia mantiqueirensis is described and illustrated as a new species with distribution for the Brazilian states of Minas Gerais and Rio de Janeiro. It is morphologically similar to A. americana but can be distinguished by the presence of canaliculated petiole, acute serrate leaf margin, glands at the apex of the margin serrations that are rounded to concave and projected outwards from the leaf blade, upper portion of the pedicel winged and seeds with tiny dorsal wings. Taxonomic description, comments, and geographical distribution information are here in provided. So far, only three populations of A. mantiqueirensis are known with only one of them recorded in a protected area. Based on the availability of suitable habitats, possible threats and future potential geographical distribution, we propose the conservation status for A. mantiqueirensis as Critically Endangered.
Peliosanthes thachii (Asparagaceae), a new species from Vietnam
Authors: LUU HONG TRUONG , NGUYEN HIEU CUONG , NAO DUY PHAP , NGUYEN TRAN QUOC TRUNG , NGUYEN-LE XUAN BACH
Published: August 2024

Peliosanthes thachii is described and illustrated as a new species endemic to southern Vietnam. This is the fifth species found for the Neolourya group as it has a slender tortuous style with the stigma positioned above the level of anthers and an inferior ovary. The new species is morphologically closest to P. curviandra but it is distinguishable from all the others of the group by having smaller dimension leaves and floral parts, spherical and hardly open perianth, short and strongly tortous style and purple ovules. The data on phenology, distribution, and provisional assessment of conservation status of the new taxon are provided.
A new species of Wongia (Papulosaceae, Sordariomycetes) from Taiwan
Authors: KUO CHANG-HSIN , HSIEH SUNG-YUAN , GOH TEIK-KHIANG
Published: August 2024

Wongia miscanthi sp. nov. from decaying culms of Miscanthus floridulus submerged in freshwater streams at Wufeng District, Taiwan, is described and illustrated, based on two collections. This new species was identified based on morphological comparison and multi-locus phylogenetic analyses of combined ITS, LSU, SSU, rpb2, and tef1a sequence dataset. Intraspecific variability between the two collections is discussed. A synopsis of Wongia species is compiled for comparison and a taxonomic key to the species is provided as an aid to their identification.
Contribution of the Triglycerides-Glucose Index (TyG) in the Assessment of Insulin Resistance in Pregnant Women During an OGTT Test
Authors: Souleymane Thiam , Yaya Soumah , Adourahmane Samba , Fatou Diedhiou , Thorpe Dia , Ramatoulaye Ba , Racine Tounkara , Medece Agossou , Fatou Coly , N. dande Diouf , Arame Ndiaye , Dominique Doupa , Fatou Cisse , Alassane Diatta , Fatou Diallo
Published: August 2024

The Triglyceride-Glucose (TyG) index is a marker used to assess insulin resistance which is associated with the occurrence of gestational diabetes. The aim of this study is to determine the benefit of the TyG within the diagnosis of insulin resistance in pregnant women in an orally induced hyperglycaemia test. This study was conducted at the Department of Biochemistry, at Aristide le Dantec University Hospital in collaboration with the department of gynaecology. Women with fasting blood glucose < 0.92 g/L at 12 weeks of age benefited from the OGTT 75 test following the WHO protocol. The TyG index was calculated using the formula: Ln [fasting triglyceridemia (mg/dL) × fasting blood glucose (mg/dL)]/2. Data were analysed using SPSS v.26 and a p< value of 0.05 was considered statistically significant. A total of 102 patients were included in the study with a mean age of 29± to 5.9 years. The OGTT 75 test was positive in 24 women (23.5%) with a predominance in the third trimester (19.4%). TyG values were significantly higher in women with gestational diabetes (8.76, ±0.5vs8.2±, 0.5; p<0.0001), in contrast to the HOMA index (6.43, ±16.8, ±1.15±, 0.9; p=0.138). The AUC of the ROC curve for the TyG-H0, TyG-H1 and TyG-H2 indices were 0.808 (95% CI)=0.70-0.92), 0.808 (95% CI)=0.698-0.918), 0.818 (95% CI)=0.70-0.93, respectively. For the HOMA-IR index, the AUC was 0.799 (95% CI = 0.69-0.91). The cut-off value for the TyG-H1 index was 9.5 with a sensitivity and specificity of 79.2% and 71.8%, respectively. The TyG index is a better way to assess the level of insulin resistance in pregnant women than using the HOMA index, especially after the first hour of a glucose load of 75g.
Determinants of Adoption of Improved Sorghum Varieties by Small-Scale Farmers in Selected Districts of Western Oromia
Authors: Abebe Galmesa
Published: August 2024

Achieving national food security and diversifying export earnings from agricultural products is one of the major challenges currently facing developing countries like Ethiopia. Ethiopia is the largest producer of sorghum in Africa, contributing to ensuring food security in the country. Despite the high production potential and the economic importance of the crop, the adoption, and dissemination of improved sorghum varieties are constrained by various factors. To this end, this study aimed to identify determinants of adoption of improved sorghum varieties in selected districts of Western Oromia Region, Ethiopia with the specific objectives of identifying factors affecting adoption and assessing factors hindering the production of improved sorghum varieties. The study was based on cross-sectional data from 154 randomly selected sorghum-producing farmers. Descriptive and econometric analyses were used to analyze data. The results show that about 14.94% and 85.06% were adopters and non-adopters of the crop respectively. Probit model results showed that education and extension service affected the probability of adoption of improved sorghum varieties positively and significantly while TLU affected it negatively and significantly. Untimely availability of improved seed, Price of seed, Quality of improved seed, unavailability of credit to buy seed, Untimely availability of fertilizer, High price of fertilizer, Access to market information, Low grain price, and Pests and disease are the major constraints that affect sorghum production in the study area. This study suggests the high importance of institutional and government support in education, Extension service, and improved cows than a large number of local breeds. Therefore, policy and development interventions should give emphasis on the improvement of such institutional support systems so as to achieve the adoption practice which increases the production and productivity of small-scale farmers.
Assessment of Job Satisfaction and Associated Factors Among Health Professionals Working at Public Hospitals in Arsi Zone, Oromia Regional State, Ethiopia/2021
Authors: Gebi Ashim , Aredo Melese , Gebre Dejene , Tejineh Solomon , Teshome Getu , Batu Dida
Published: August 2024

Background: Job satisfaction encompasses the array of attitudes that employees hold towards their work. Various factors influence job satisfaction, including salaries, benefits, allowances, pension funds, working hours, and the level of respect received in the workplace. In Ethiopia, approximately 50% of nurses employed in public health facilities express dissatisfaction, citing reasons such as lack of motivation, inadequate salary, limited training opportunities, and insufficient human resources. Objective: This study aimed to evaluate job satisfaction and its determinants among health professionals working in public primary hospitals in Arsi Zone, Oromia Regional State, Ethiopia in 2021. Methods: An institutional-based cross-sectional study design was utilized, involving 207 health professionals selected systematically from public primary hospitals in Arsi Zone. Data were cleaned, coded, entered into EpiData 7, and analyzed using SPSS version 21. Multiple logistic regression analysis was conducted to identify statistically significant associations between dependent and independent variables and to predict factors influencing job satisfaction. Results: The study revealed that 71 (35.3%) health professionals expressed agreement that they would choose the same career if given the chance again. While 60 (29.9%) respondents perceived personal growth in their work, 124 (61.7%) did not experience any personal development. A majority of participants (78.1%) reported having adequate opportunities for professional growth, with 125 (62.1%) indicating satisfaction in their profession. Multivariate analysis identified age, work experience, and income as significant factors influencing job satisfaction among health professionals. Conclusions and Recommendations: The study found an overall low level of job satisfaction among health professionals. Age, work experience, and average monthly income emerged as key factors affecting job satisfaction in this group. The government should implement effective policies addressing all determinants of job satisfaction, improve payment structures, create conducive work environments, recognize achievements, and establish mechanisms for remote retention of staff. Hospital administrators should enhance work conditions, increase rewards, and prioritize the professional development of employees to boost staff job satisfaction.
Identification of MIMO Nonlinear Gaussian Time-Varying System Based on Multi-Dimensional Taylor Network Multi-Level Approximation
Authors: Li Jiefei , Hu Shaolin
Published: August 2024

Aiming at the problems of identification difficulties and low identification accuracy in modelling and identification of multiple-input multiple-output (MIMO) nonlinear Gaussian time-varying systems, this paper proposes an identification scheme based on the step-by-step approximation of multidimensional Taylor network (MTN). The aim of this paper is to improve the modelling of complex nonlinear systems so as to improve the prediction performance and control effect of the system. Different from the traditional multidimensional Taylor network identification method, this method adopts an order-by-order approximation strategy, which seeks its parameters sequentially from the lower order to the higher order, and continuously optimises the parameter weights during the parameter seeking process. Firstly, the nonlinear function model is approximated as a polynomial form by the order-by-order Taylor expansion, and then the weight parameters of each order of the Taylor expansion are calculated and updated step by step by using the algorithm based on the Variable Forgetting Factor Recursive Least Squares (VFF-RLS) method. Through iterative optimized of these parameters, dynamic weight assignment to each order of the Taylor expansion is achieved. A parameter-identified nonlinear function model is finally obtained, which can more accurately describe the dynamic behaviour and characteristics of the system. Finally, an arithmetic simulation is carried out through an example to verify the effectiveness of the proposed method.
Optimizing Available Resources to Revitalize the Tourism Economy of the Rural Commune of Iarintsena
Authors: Fabien Randrianasolo , Camille Andriamiadanomenjanahary
Published: August 2024

This article is the product of in-depth research and strategies to mobilize and empower local stakeholders and tries to suggest some approaches, as well. Two methodologies are taken into account: The positive normative and SWOT analysis (Strength, Weakness, Opportunity and Threat). The latter enables us to present and identify the tourism development potential and issues. In 2021, Madagascar generated around 111.00 million US dollars, corresponds to 0.73 percent of its GDP in the tourism sector alone. Driven by favorable base effects, growth expected to accelerate to an average of 4.6% over 2024-26. Nowadays, tourism can offer high opportunities for cultural exchange between visitors and local communities. The research results from the project simulation works were used to draw up a budget for tourism activities. The rural commune of IARINTSENA, located in the south-eastern part of the Haute Matsiatra region and a few kilometers from the Ambalavao district, has tourism assets that appear to be weakened by innumerable constraints. The design of the commune's development strategies should take into account the realities and aspirations of the local population. Highlighting the commune's specific tourist attractions should encourage technical and financial partners to invest in the tourism development project. It’s important to put the touristic specificity of IARINTSENA in evidence in order to incite the technical and financial partners.
A New Music Composition Technique Using Natural Science Data
Authors: Lee Joungmin
Published: August 2024

The relationship of music and mathematics are well documented since the time of ancient Greece, and this relationship is evidenced in the mathematical or quasi-mathematical nature of compositional approaches by composers such as Xenakis, Schoenberg, Charles Dodge, and composers who employ computer-assisted-composition techniques in their work. This study is an attempt to create a composition with data collected over the course 32 years from melting glaciers in seven areas in Greenland, and at the same time produce a work that is expressive and expands my compositional palette. To begin with, numeric values from data were rounded to four-digits and converted into frequencies in Hz. Moreover, the other data are rounded to two-digit values that determine note durations. Using these transformations, a prototype composition was developed, with data from each of the seven Greenland-glacier areas used to compose individual instrument parts in a septet. The composition Contrast and Conflict is a pilot study based on 20 data sets. Serves as a practical example of the methods the author used to develop and transform data. One of the author’s significant findings is that data analysis, albeit sometimes painful and time-consuming, reduced his overall composing time. The variety and richness of data that exists from all academic areas and disciplines conceivably provide a rich reservoir of material from which to fashion compositions. As more composers explore this avenue of work, different methodologies will develop, and the value of works produced by this method will be evaluated.
Biogenically Synthesized ZnO and Cu-Doped ZnO Nanoparticles: Effect of Cu-Dopent Concentration and Annealing on Morphology and Optical Properties
Authors: Subramanian Parameswaran , Kumaran Rethikala , Nageri Manoj
Published: August 2024

In this work, ZnO nanoparticles and Cu-doped ZnO nanoparticles were biogenically synthesized using precipitation method in Cissus quadrangularis plant extract medium. The influence of Cu dopant on the crystalline structure, optical properties, and morphology of ZnO was investigated. The samples were characterized by XRD, FTIR, UV–vis spectroscopy and SEM. XRD patterns confirmed the wurtzite formation of doped and undoped ZnO nanoparticles. The average crystallite size of the neat and Cu-doped samples was ~18 nm irrespective of the amount of dopant. The annealing process enhanced the size of both the neat and Cu-doped samples. However, the influence on the size is less prominent in the Cu-doped sample than in the neat sample. The UV-visible spectral analysis shows that all the synthesized doped and undoped nano zinc oxides absorb at ~400nm. The band gap energy of Cu-doped ZnO particles was greater for unannealed samples whereas it was appreciably lowered on annealing for Cu-doped samples. SEM analysis shows rod-like morphology for the unannealed and annealed undoped zinc oxides. It is changed to flower-like morphology with the addition of 5mM Cu2+ and then to nano sheet-like structure with the incorporation of higher amount of Cu2+ ions. Annealing of zinc oxide samples leads to the smoothening of the surfaces with a change in morphology for the ZnO nanoparticles.
The Importance of the Use of Unmanned Aerial Vehicles (UAVs) in the Oil and Gas Industry
Authors: Kon Taha
Published: August 2024

The oil and gas industry, renowned for its extensive and intricate operations, confronts numerous challenges in maintaining and inspecting its infrastructure. Traditional inspection methodologies, often reliant on manual labor, are not only time-consuming and costly but also expose workers to hazardous conditions. These conventional methods necessitate the shutdown of operations, leading to considerable productivity losses and elevated costs. Over the past decade, the advent of unmanned aerial vehicles (UAVs) has introduced a transformative technology in this sector, providing a safer, more efficient, and cost-effective alternative to traditional inspection techniques. UAVs, equipped with advanced sensors and high-resolution cameras, facilitate detailed visual and thermal inspections of critical assets such as pipelines, flare stacks, and offshore platforms. These capabilities enable companies to perform routine inspections without halting operations, thereby minimizing downtime and operational disruptions. The implementation of UAV technology has notably enhanced safety by reducing the need for human intervention in perilous environments. For instance, the traditional inspection of flare stacks necessitates workers to ascend these structures, posing significant risks. UAVs obviate this requirement by delivering real-time visual data from secure distances. Moreover, the precision and accuracy inherent in UAV inspections contribute to the early detection of defects and potential issues, allowing for prompt maintenance and repairs, which further augment safety and operational efficiency. The environmental benefits of UAV technology are also noteworthy. By diminishing the reliance on heavy machinery and extensive transportation typically associated with inspections and maintenance, UAVs aid in reducing carbon emissions, thus aligning with the industry's sustainability objectives. In summary, the integration of UAVs into the oil and gas industry's inspection protocols represents a significant technological advancement. This integration aligns with the sector's goals of enhancing safety, efficiency, and environmental sustainability, marking a pivotal step forward in the industry's evolution.
Statistical Response of ENSO Complexity to Initial Condition and Model Parameter Perturbations
Authors: Andreou Marios , Chen Nan
Published: August 2024

Studying the response of a climate system to perturbations has practical significance. Standard methods in computing the trajectory-wise deviation caused by perturbations may suffer from the chaotic nature that makes the model error dominate the true response after a short lead time. Statistical response, which computes the return described by the statistics, provides a systematic way of reaching robust outcomes with an appropriate quantification of the uncertainty and extreme events. In this paper, information theory is applied to compute the statistical response and find the most sensitive perturbation direction of different El Niño–Southern Oscillation (ENSO) events to initial value and model parameter perturbations. Depending on the initial phase and the time horizon, different state variables contribute to the most sensitive perturbation direction. While initial perturbations in sea surface temperature (SST) and thermocline depth usually lead to the most significant response of SST at short and long ranges, respectively, initial adjustment of the zonal advection can be crucial to trigger strong statistical responses at medium range around 5–7 months, especially at the transient phases between El Niño and La Niña. It is also shown that the response in the variance triggered by external random forcing perturbations, such as the wind bursts, often dominates the mean response, making the resulting most sensitive direction very different from the trajectory-wise methods. Finally, despite the strong non-Gaussian climatology distributions, using Gaussian approximations in the information theory is efficient and accurate for computing the statistical response, allowing the method to be applied to sophisticated operational systems.

Significance Statement

The purpose of this work is to better understand how El Niño–Southern Oscillation (ENSO) responds to changes in its initial state and internal dynamics or external forcings. A statistical quantification of this response allows for the comprehension of the triggering conditions and the effect of climate change on the occurrence frequency and strength of each type of ENSO event. Such a study also allows to detect the most sensitive perturbation directions, which has practical significance in guiding anthropogenic activities. The approach used to study the response in this work is through the framework of information theory, which allows for an unbiased and robust assessment of the statistical response that is not affected by the turbulent dynamics of the system.
Impact of Atmospheric River Reconnaissance Dropsonde Data on the Assimilation of Satellite Radiance Data in GFS
Authors: Zheng Minghua , Delle Monache Luca , Wu Xingren , Kawzenuk Brian , Ralph F. Martin , Zhu Yanqiu , Torn Ryan , Tallapragada Vijay S. , Zhang Zhenhai , Wu Keqin , Wang Jia
Published: August 2024

Satellites provide the largest dataset for monitoring the earth system and constraining analyses in numerical weather prediction models. A significant challenge for utilizing satellite radiances is the accurate estimation of their biases. High-accuracy nonradiance data are commonly employed to anchor radiance bias corrections. However, aside from the impacts of radio occultation data in the stratosphere, the influence of other types of “anchor” observation data on radiance assimilation remains unclear. This study provides an assessment of impacts of dropsonde data collected during the Atmospheric River (AR) Reconnaissance program, which samples ARs over the northeast Pacific, on the radiance assimilation using the Global Forecast System (GFS) and Global Data Assimilation System at the National Centers for Environmental Prediction. The assimilation of this dropsonde dataset has proven crucial for providing enhanced anchoring for bias corrections and improving the model background, leading to an increase of ∼5%–10% in the number of assimilated microwave radiance in the lower troposphere/midtroposphere over the northeast Pacific and North America. The impact on tropospheric infrared radiance is not only small but also beneficial. Impacts of dropsondes on the use of stratospheric channels are minimal due to the absence of dropsonde observations at certain altitudes, such as aircraft flight levels (e.g., 150 hPa). Results in this study underscore the usefulness of dropsondes, along with other conventional data, in optimizing the assimilation of satellite radiance. This study reinforces the importance of a diverse observing network for accurate weather forecasting and highlights the specific benefits derived from integrating dropsonde data into radiance assimilation processes.

Significance Statement

This study aims to evaluate the impact of aircraft reconnaissance dropsondes on the assimilation of satellite radiance data, utilizing observations from the 2020 Atmospheric River Reconnaissance program. The key findings reveal a substantial enhancement in the model first guess and improved estimates of radiance biases. Notably, there is a significant 5%–10% increase in microwave radiance observations over the northeastern Pacific and North America, with positive yet modest effects observed in tropospheric infrared radiance. These findings underscore the crucial role of atmospheric river reconnaissance dropsondes as anchor data, enhancing the assimilation of radiance observations. In essence, the inclusion of these dropsondes in routine networks is particularly valuable for optimizing data assimilation in regions with sparse observational data.
Citizens and Their Bots That Sniff Corruption: Using Digital Technology to Monitor and Expose Politicians Who Misuse Public Money
Authors: Odilla Fernanda , Veloso Clarissa
Published: August 2024

This article explores the advantages and constraints affecting anti-corruption grassroots initiatives that employ the “naming and shaming” strategy. It questions why activists choose such a confrontational approach while examining the cases of two Brazilian anti-corruption bottom-up initiatives. Both fight corruption by deploying bots to assist in auditing congressional members’ expenses, and then use social media to expose their suspicious findings. Findings, based on a qualitative analysis, show that publicly exposing those who misuse public money was a tactic adopted only when the expected response from law enforcement and anti-corruption authorities fell short. This study suggests that having a participatory accountability system is insufficient and considered disappointing if no inquiries and sanctions follow civic action. As an unforeseen effect, the digital exposure of officeholders garnered media attention and expanded the initiatives’ support base. Nevertheless, activists acknowledge the risks associated with their belligerent activities and the challenges of financing, maintaining engagement, and expanding the scope of their actions, despite the high expectations that digital technologies would reduce costs and support collective action.
A Pilot Study on the Drug Price Revision Strategy in Japan: A Comparison Among Fiscal Years 2018, 2020, and 2022
Authors: Nakagawa Naoto , Konno Mizuha , Kashiwabara Masami , Shimoji Shinya , Mochimaru Jun , Inoue Tadao , Lai Leanne
Published: August 2024

Objective: Japan has resumed its health technology assessment to decide how to reduce high-cost drug prices. While drug price rules in Japan are comprehensive, they do not necessarily capture differences in product characteristics. This study examined the drug price revision strategy in Japan using migraine treatment with triptans as an example. Cost data from fiscal years (FY) 2018, 2020, and 2022 were utilized. Methods: A cost-utility analysis was conducted from the perspective of healthcare payers, focusing on Japanese patients aged over 18 years experiencing migraines. The study employed a base-case model with probabilities derived from a network meta-analysis. Direct costs included medical and drug costs. Effectiveness was assessed using the European Quality of Life 5-dimensions—3-level questionnaire. Deterministic and probabilistic sensitivity analyses were conducted to examine the level of uncertainty. Results: In FY2018, sumatriptan and eletriptan were cost-effective; however, the other triptans were dominated by sumatriptan. In FY2020, sumatriptan and eletriptan were cost-effective, and rizatriptan was extended-dominated; nevertheless, the other triptans were dominated by sumatriptan. In FY2022, naratriptan and eletriptan were cost-effective; however, the other triptans were dominated by naratriptan. The hierarchy of triptan strategies varied in each fiscal year. Conclusions: This study provides valuable insights into the drug price revision strategy in Japan. The variations could be problematic because in Japan, formulary management of triptans, for example, those for migraine, may face revaluation every other year. Discussions regarding this issue will be further explored in the future.
Nebulae or galaxies? The history of a change in astronomical terminology
Authors: Kragh Helge
Published: August 2024

While today the term ‘galaxy’ is a household word primarily associated with the huge congregations of stars far outside the Milky Way, until about 1950 these structures were generally known as ‘nebulae’. Although the singular form ‘galaxy’ was commonly used, it was typically considered as just another word for the Milky Way. Edwin Hubble’s celebrated discovery in the 1920s of the extragalactic nature of the spirals was for a long time referred to as the discovery of ‘extragalactic nebulae’, whereas the plural term ‘galaxies’ was only employed by a minority of astronomers. In fact, it took until about 1960 before our current usage became commonly accepted and the spiral nebulae became spiral galaxies. The paper focuses on the words of and related to extragalactic astronomy as they were used historically in the period from about 1920 to 1960.
An experimental investigation of nano clay and functionalized nano graphene oxide effects on ablation of carbon/phenolic nanocomposites
Authors: Hosseini Kordkheili Seyed Ali , Jafari HR
Published: August 2024

This work aims to study thermal stability and ablative behaviors of Carbon/Phenolic composites containing nano clay, nano graphene oxide and hybrid additives. To this end a detailed explained and illustrated process is involved to synthesize factionalized graphene oxide based on Hummers method. The XRD test result shows a major shift in basal plane reflection to below 2θ = 20° in the provided spectrum, which indicates achievement in the functionalization process. Prepared nanoparticles suspensions are then mixed by resol resin with desire wt% to outcome nanocomposites. An in-depth analysis of SEM images with focus on the dispersion, morphology, and interaction of the nanofillers with the resin matrix reveals that nanoparticles are dispersed properly with no agglomeration. 200 gr/m2 carbon woven fabric is then impregnated with prepared nanocomposites employing an own made prepreg machine to use to construct standard flexural as well as oxy acetylene test specimens. Using bending test, thermogravimetric analysis and oxyacetylene torch test, effects of different percentages of considered nanoparticles on the mechanical properties, thermal stability and ablative of carbon/phenolic composites are assessed and the results are reported. According to the results, adding only 0.1 wt% of nano graphene oxide increases char yield around 5% and remain back surface temperature under 100°C during flame test. Moreover samples with 0.2 wt% of nano clay and hybrid (0.05 wt% nano graphene oxide and 0.1 wt% nano clay) additives provides best reaming amount of solid.
A patient perspective of supporting mental wellbeing in ophthalmology through Five Stages of Sight Loss
Authors: Thurston Mhairi
Published: August 2024

In this autoethnography, the experience of being a patient in an ophthalmology clinic is explored, within the context of the Five Stages of Sight Loss Model. The author describes her lived experience of diagnosis and critically examines her experience of receiving treatment and care within an ophthalmology clinic. The literature focusing on supporting patient mental wellbeing in an ophthalmology clinic is considered, and a patient perspective on improving support for mental wellbeing is proposed. Consistent care, clinical skills, the interpersonal skills of the ophthalmologist, and shared decision-making with patients emerge as important factors. The concept of ‘embedded counselling’ is considered.