bluuebunny/crossref_metadata_2025 huggingface dataset:
DEVELOPING INTERNATIONAL POLICY GUIDELINES FOR MANAGING CROSS-BORDER INSOLVENCIES IN THE DIGITAL ECONOMY
Authors: Etinosa Igbinenikaro  , Adefolake Olachi Adewusi
Published: April 2024

The rapid growth of the digital economy has transformed global commerce, introducing new complexities and challenges, particularly in the realm of cross-border insolvencies. As businesses increasingly operate across national boundaries and rely on digital assets and data, traditional bankruptcy laws struggle to effectively address the intricacies of digital insolvencies. This review outlines the need for developing international policy guidelines to manage cross-border insolvencies in the digital economy. Cross-border insolvencies in the digital economy present unique challenges, including jurisdictional conflicts, the treatment of digital assets and data, and coordination among diverse stakeholders. Existing international legal frameworks, while providing some guidance, are often inadequate in addressing these complexities. Thus, there is a pressing need for harmonized policy guidelines to facilitate efficient and fair resolution of digital insolvencies. The proposed policy guidelines aim to achieve several objectives. Firstly, they advocate for the harmonization of laws and regulations across jurisdictions to provide clarity and consistency in cross-border insolvency proceedings. Secondly, they call for the establishment of a framework for recognizing and enforcing foreign insolvency proceedings, ensuring equitable treatment of creditors and stakeholders. Additionally, the guidelines emphasize the protection and appropriate treatment of digital assets and data, reflecting their growing importance in the digital economy.

Implementation strategies include capacity building for legal professionals, mechanisms for dispute resolution and coordination, and ongoing monitoring and evaluation of policy effectiveness. Case studies and best practices will be utilized to illustrate successful cross-border insolvency resolutions in the digital economy, offering valuable insights for policy development and replication. In conclusion, developing international policy guidelines for managing cross-border insolvencies in the digital economy is crucial for promoting economic stability, facilitating global commerce, and safeguarding the interests of creditors and stakeholders in an increasingly interconnected world.

Keywords:  Bankruptcy, Law, International Policy Guidelines, Cross-Border, Insolvencies, Digital Economy.
THE ROLE OF PUBLIC-PRIVATE PARTNERSHIPS IN BUILDING CLEAN ENERGY INFRASTRUCTURE IN THE UNITED STATES AND NIGERIA
Authors: Munachi Chikodili Ugwu  , Adefolake Olachi Adewusi  , Naomi Emeka Nwokolo
Published: April 2024

Public-Private Partnerships (PPPs) play a pivotal role in the development of clean energy infrastructure in both the United States and Nigeria, offering a collaborative framework that leverages the strengths of both public and private sectors. In the United States, PPPs have been instrumental in advancing renewable energy projects, such as wind farms and solar installations, through joint ventures between government entities and private companies. These partnerships capitalize on government incentives, such as tax credits and grants, to attract private investment and stimulate innovation in clean energy technologies. Moreover, PPPs in the US often involve long-term contracts that provide stability and assurance to private investors, facilitating the financing and implementation of large-scale projects. In Nigeria, where energy access remains a significant challenge, PPPs offer a promising approach to address the country's growing energy needs while transitioning to cleaner sources. The Nigerian government has been actively promoting PPPs in the energy sector to mobilize private capital and expertise for the development of renewable energy infrastructure. These partnerships aim to diversify Nigeria's energy mix, reduce dependency on fossil fuels, and improve energy access in rural and underserved areas. By partnering with private investors, the government seeks to overcome financial constraints and institutional barriers that have historically hindered the expansion of clean energy infrastructure. Despite their potential benefits, PPPs in both countries face various challenges, including regulatory complexities, political risks, and issues related to project financing. In the United States, uncertainties surrounding government policies and regulations can impact investor confidence and project viability. Similarly, in Nigeria, factors such as corruption, bureaucracy, and inadequate legal frameworks can impede the effective implementation of PPPs. Addressing these challenges requires a coordinated effort from governments, private sector stakeholders, and civil society to create an enabling environment for sustainable investments in clean energy. Overall, the role of PPPs in building clean energy infrastructure transcends national boundaries, offering a collaborative solution to global energy challenges. By fostering partnerships that combine public resources with private sector innovation and efficiency, PPPs have the potential to accelerate the transition to a low-carbon future while driving economic growth and promoting energy security for all.

Keywords:  Public-Private Partnerships, Clean Energy, USA, Nigeria, Innovation.
ETHICAL SUPPLY CHAIN MANAGEMENT: BALANCING PROFIT, SOCIAL RESPONSIBILITY, AND ENVIRONMENTAL STEWARDSHIP
Authors: Nsisong Louis Eyo-Udo  , Agnes Clare Odimarha  , Olaniyi Olufemi Kolade
Published: April 2024

This review paper explores the intricate balance between profit, social responsibility, and environmental stewardship in ethical supply chain management. It delves into the challenges businesses face in integrating ethical practices within their supply chains, highlighting the conflict between profitability and ethical imperatives. The paper proposes a multifaceted approach to navigate these complexities, encompassing best practices, adherence to policies and regulations, and leveraging technology and innovation. This lens emphasizes the importance of ethical considerations in enhancing corporate sustainability, competitiveness, and stakeholder trust. Recommendations for businesses and directions for future research are provided, aiming to further the understanding and implementation of ethical supply chain management strategies that benefit both businesses and society.

Keywords:  Ethical Supply Chain Management, Corporate Social Responsibility, Environmental Stewardship, Sustainability, Technology and Innovation, Stakeholder Engagement.
PROMOTING CUSTOMER-BASED BRAND EQUITY THROUGH PRODUCT REJUVENATION: A STUDY OF RITE FOODS LIMITED, NIGERIA
Authors: Dibie Raphael Ndidi  , Olannye A. Peter  , Kifordu A. Anthony
Published: April 2024

The study examined the effect of product rejuvenation on customer-based brand equity of Rite Foods Limited. Primary data was sourced through the administration of a structured questionnaire to the employees of the selected firm, while secondary data was obtained through the review of related literature. The study adopted the descriptive research design, which aids the researcher in collecting quantitative data used to address the relationship between the dependent and independent variables. A total of 188 copies of the questionnaire were administered adopting random sampling techniques. Data collected were analyzed using Pearson’s correlation coefficient and hypotheses were tested using multiple regression. The findings revealed that rebranding, brand positioning, brand extension, and product differentiation has positive effect on customer-based brand equity. The study concluded that product rejuvenation is a strategic process initiated to improve the existing product, process, or brand to meet the changing demands and requirements of consumers in the evolving market. It is a corrective measure applied when the business or the product is at the maturity or decline stage (alarming phase) of its life cycle and is on the verge of becoming obsolete. Therefore, it must be carefully planned such that the essence of the entity remains intact even though its products are modernized.

Keywords: Customer-based Brand Equity, Brand Positioning, Rebranding, Product Differentiation, Brand Extension.
NATURAL GALACTAGOGUES IN NIGERIA AND THE US: MECHANISMS, EFFICACY, AND SAFETY
Authors: Deborah Aanuoluwa Soyombo
Published: April 2024

Natural galactagogues are substances that are believed to promote lactation by increasing milk production in breastfeeding mothers. This review examines the use, scientific evidence, and regulatory status of natural galactagogues in Nigeria and the US, focusing on their mechanisms, efficacy, and safety. In both Nigeria and the US, various natural substances have been traditionally used to support lactation. These substances include herbs such as fenugreek, blessed thistle, and fennel seed, as well as foods like oats and barley. While these substances have been used for centuries and are believed to have lactogenic properties, scientific evidence supporting their efficacy is limited. In Nigeria, traditional healers and herbalists often prescribe natural galactagogues to breastfeeding mothers to enhance milk production. These practices are deeply rooted in cultural beliefs and are often passed down through generations. However, the scientific evidence supporting the use of these substances is scarce, and their safety and efficacy remain uncertain. In the US, natural galactagogues are also commonly used by breastfeeding mothers seeking to increase milk supply. While some studies have suggested that certain herbs and foods may have lactogenic effects, the overall evidence is inconclusive. Additionally, the regulatory status of natural galactagogues in the US varies, with some substances being classified as dietary supplements and others as foods. Overall, the use of natural galactagogues in Nigeria and the US reflects a cultural and historical belief in their efficacy. However, more research is needed to fully understand the mechanisms, efficacy, and safety of these substances. Regulatory agencies in both countries should also continue to monitor the use of natural galactagogues and provide guidance to ensure their safe and appropriate use by breastfeeding mothers.

Keywords: Natural, Galactagogues, Mechanism, Efficacy, Safety.
THE PYROLYSIS OF HIGH-DENSITY POLYETHYLENE (HDPE) AND POLYPROPYLENE (PP) PLASTIC WASTE BLEND
Authors: Marwani Marwani , Trifarizy Muhammad David
Published: April 2024

Plastic waste is a growing problem that hurts the environment. The pyrolysis method converts plastic waste into alternative fuels to address this issue. This study aimed to investigate the impact of temperature on the characteristics of pyrolysis oil produced from a combination of High-Density Polyethylene (HDPE) and PolyPropylene (PP) plastic waste. The study focused on the resulting pyrolysis oil's volume, density, viscosity, and calorific value. The study results showed that the highest pyrolysis oil yield was obtained at 450ºC, with a volume of 350 ml. The density of the pyrolysis oil ranged from 670-790 kg/m3, while the viscosity ranged from 1.611-2.401 cP. The calorific value of the pyrolysis oil ranged from 7393.7584-8946.3759 cal/gr. The results demonstrate that the temperature significantly impacts the characteristics of the resulting pyrolysis oil. The study findings could be useful in optimizing the pyrolysis process to obtain high-quality oil from mixed plastic waste streams, thereby reducing plastic waste and providing an alternative energy source. The study highlights the potential for converting mixed plastic waste into alternative fuels through pyrolysis.
EXPERIMENTAL STUDY OF VERTICAL AXIS WIND TURBINE WITH PRE-SWIRL AUGMENTED
Authors: Riady M Ihsan , Santoso Dyos , Ervega Frandiaz Agustan
Published: April 2024

The paper presents an experimental investigation on a vertical axis wind turbine that utilizes pre-swirl augmentation through a concentric stator and rotor system. The study's main objective is to demonstrate that incorporating a stator as a guide blade can significantly enhance the turbine's performance. The rotor is positioned in the inner region of the turbine and is rotated by the flow induced by the stator surrounding it in the outer region. The stator accelerates the incoming wind before it reaches the rotor. The turbine has five rotor blades and has been tested with stator guide blades varying from zero to six and twelve. Both the guide rotor and blades use a modified cp-100-050-gn cambered plate airfoil. The tests were conducted at an average wind speed of 4 m/s. The results indicate that utilizing a stator with six guide blades leads to a 52% increase in the power coefficient, while a stator with 12 guide blades yields a slightly higher increase of 58%. Moreover, the turbine with a stator comprising 12 guide blades takes less time to attain maximum speed under no-load conditions than the one with a stator with six guide blades.
EFFECTS OF BLADE HEIGHT ON THE EFFICIENCY OF GRAVITATIONAL WATER VORTEX TURBINE
Authors: Sinaga Jorfri Boike , Irsyad Muhammad , Yonanda Ahmad , Ibrahim Gusri Akhyar , Sinaga David , Topan Tri
Published: April 2024

This paper presents the results of a study on the effect of blade height on the efficiency of a free-vortex water turbine. Laboratory experimentation was conducted to determine the turbine's shaft power generation and efficiency. Water turbines with six blades and four different heights (208 mm, 248 mm, 288 mm, and 320 mm) were built and tested to determine the most appropriate blade height. The turbines were tested in a conical basin with inlet and outlet diameters of 600 mm and 100 mm and a height of 800 mm, at volume flow rates of 0.0088 m³/s, 0.0105 m³/s, and 0.0108 m³/s. The results showed that the turbine with a blade height of 288 mm was the most appropriate, yielding the highest efficiency of 30.46% at a water flow rate of 0.0108 m³/s.
THE POTENTIAL OF EVAPORATION BOATS WASTE AS A CRUCIBLE MATERIAL FOR CASTING: A REVIEW
Authors: Habiby M. Nuril Anwar Habiby , Rusiyanto Rusiyanto , Widodo Rahmat Doni
Published: April 2024

Industry in Indonesia continues to experience development in line with advances in science and technology, and this is because the industrial sector makes the most significant contribution to the national economy. However, industrial operations that are getting bigger can produce various kinds of waste, one of which is waste from the processing of plastic metallization applications and modern vacuum coating on food packaging, namely evaporation boats. The result of this waste is substantial because, in its application, evaporation boats will always be used as long as plastic food packaging continues to be produced around the world, so it is necessary to have handling for environmental sustainability in the future. Evaporation boat waste is waste that cannot be decomposed but can withstand heat and be used as a refractory material, especially as a primary material for making crucibles. This article presents a literature review focusing on the nature of evaporation boat waste and its effect on the mechanical and physical properties of the crucible material used in metal casting.
ASSESSMENT OF REFRACTIVE ERRORS IN SCHOOL GIRLS IN A RURAL SETTING
Authors: Lodhi Hifza Noor , Naima Khalid  , Madiha Akram  , Tashfeen Ikram  , Muniza Saeed  , Sadia Chiragh
Published: April 2024

Background: Among children, undiagnosed refractive error is the second most common cause of curable blindness and the major cause of visual disability these days. Children often do not complain of visual problems and may not even be aware of their symptoms. Ophthalmic screening programs in school children are not only essential but are also valuable School screening programs assist in early detection of amblyopia and its risk factors such as strabismus, refractive errors and media opacities

Methods: A total of 155 schoolgirls between ages 5 to 18 years were included in the screening process at a Government Higher Secondary School in April 2019. The students were asked to fill in a self-devised questionnaire for a superficial ocular assessment. Next, visual acuity was measured with Snellen distant vision chart. Data was analyzed using IBM SPSS Version 23. Data was checked for normality of distribution by Shapiro-Wilk test. Frequency and percentages of refractive errors were determined. A p-value ≤ 0.05 was considered statistically significant.

Results: The frequency of girls having right eye error was more than those having it in left eye and the percentage of girls having failed visual acuity in either eye i.e VA<6/12 was 17.4%. Pearson Chi Squared test was applied to determine any relationship between categorical variables and it showed significance between reading from books, threading the needle 0.000 and parents wearing glasses. (p-value<0.05).

Conclusion: Awareness about causes of refractive errors must be prioritized. Annual screening should be made mandatory in schools of both urban as well as rural setting, health education programs, walks, seminars should be conducted in order to create awareness amongst the general masses, and last but not the least smartphone usage hours should be restricted in children in order to prevent them from the deleterious effects of this gadget.
ARTIFICIAL INTELLIGENCE AND MENTAL HEALTH SERVICES: A SYSTEMATIC REVIEW
Authors: Majeed Saima , Qadir Khan Altaf
Published: April 2024

Artificial Intelligence (AI) is increasingly being applied in mental health services to provide improved diagnosis, treatment, and support. This systematic review article aims to explore the current literature on the use of AI in mental health services, focusing on the effectiveness of AI-based interventions and the ethical considerations surrounding their use. The databases PsycINFO, PubMed, and Web of Science were explored for articles published between 2015 and 2022 using the following search terms: “Artificial Intelligence”, “Mental Health”, “Intervention”, and “Ethics”. A search based on inclusion and exclusion criteria ended up with 50 articles highlighting the potential of AI to enhance the efficiency and accessibility of mental health services. Further deliberation excluded 30 articles and the present systematic review has been carried out with twenty articles.  The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines resulted in stating the results of this systematic review. The results suggest that AI-based interventions have promising outcomes for improving the diagnosis and treatment of disorders related to mental health, early detection and prevention of mental disorders, improved quality of care as well as reduced cost of mental health services. However, ethical considerations, such as privacy and transparency, must be considered in the implementation of AI in mental health services, and issues related to empathy and reflective practices were also highlighted. Implications and future directions for the research were also discussed.
HEPATIC ENCEPHALOPATHY MIMICKING STROKE IN A PATIENT WITH CHRONIC LIVER DISEASE
Authors: Ghoauri Muhammad Sohail Ajmal , Butt Nauman Ismat , Qaisar Fahad , Javed Muhammad Umair , Ali Asfand Yar , Ashfaq Fahmina
Published: April 2024

Hepatic Encephalopathy is a potentially reversible life-threatening neuro-psychiatric complication of liver cirrhosis. It generally presents with sleep disturbances, drowsiness and personality changes. Focal neurological loss in form of hemiplegia is a very rare presentation of hepatic encephalopathy. A 55-year old gentleman presented with irritability, drowsiness, right sided body weakness and constipation for last 3 days. He was a diagnosed patient of Hepatitis C positive Chronic liver disease for 3 years having completed a 24-week course of oral sofosbuvir 400mg and daclatasvir 60mg. On examination, the patient was drowsy but arousable having a GCS of 12/15 (E3, V4, M5). Power of grade 4/5 was noted in both left upper and lower limb with an extensor left plantar reflex. Flapping tremors were preset and bilateral mild pitting pedal edema was noted. Abdomen was soft, non-tender, mildly distended with positive shifting dullness. A CT scan (Brain) was done to rule out intracranial bleeding and the patient was admitted on lines of ischemic stroke and hepatic encephalopathy. He had thrombocytopenia, deranged LFTs and serum ammonia level. MRI Scan (Brain) showed foci of diffusion restriction in the left periventricular region and basal ganglia and T2WI/FLAIR hyperintense signals in the periventricular region, basal ganglia and deep white matter, however MR angiography demonstrated normal cerebral vessels. He was diagnosed as having hepatic encephalopathy mimicking stroke and underlying liver cirrhosis. After initiating lactulose and Rifaximin, the patient passed stools which resulted in resolution of his symptoms. His repeat serum ammonia was within normal limits and the patient was discharged.
SKIN, SOFT TISSUE INFECTIONS AND THEIR MICROBIOLOGICAL PROFILE FROM A TERTIARY CARE HOSPITAL
Authors: Rasheed Farhan , Jamil Iqra , Gull Fraz Rai , Sultan Aisha , Bilal Muhammad , Niaz Khan Jawad
Published: April 2024

Background: Skin and soft tissue infections (SSTIs) are considered as diverse group of infections which may vary in microbial etiology and clinical presentation and ranges from simple, uncomplicated infections to severe, complicated picture. Causative organisms with antimicrobial resistance may worsen the situation.

Objectives: The aim of present study was to check the frequency and antibiotic sensitivity pattern of bacterial isolates causing SSTIs.

Methods: A retrospective study performed over a period of 3 years. Pus and wound samples were collected and were processed by using standard microbiological procedures. Confirmation of bacterial species was done by different biochemical tests. Antimicrobial susceptibility pattern (AST) was checked on Mueller-Hinton (MH) agar by disc-diffusion method according to CLSI guidelines.

Results: Among 2345 total samples, 63.1% were cultured positive. Percentage of gram-negative bacteria was 51.3% while 48.7& were gram positive. E. coli (33.7%) was most common organism among gram-negative and S. aureus (34.5%) was more prevalent among gram positive organisms. Linezolid and glycopeptides showed excellent susceptibility against gram-positive organism, while maximum resistance was observed against Co-trimoxazole and Fluoroquinolones among gram-negative isolates.

Conclusion: Changing trend of bacterial spectrum causing SSTIs along with increasing antimicrobial resistance becomes a serious health problem which limits the treatment options for such infections.
CORRELATION BETWEEN TOTAL SERUM BILIRUBIN LEVELS AND TRANSCUTANEOUS BILIRUBINOMETER VALUES IN NEONATAL JAUNDICE
Authors: Muhammad Shahid  , Anum Zia  , Aqsa Mazhar  , Faez Qasem Mohammad Hassan  , Saad Muhammad Shahid  , Nida Aslam
Published: April 2024

Background: Jaundice in newborns is a prevalent postnatal complication, typically benign in nature. To assess neonatal jaundice, the development of non-invasive techniques, such as the transcutaneous bilirubinometer, has proven instrumental. This study focuses on evaluating neonatal bilirubin levels using transcutaneous bilirubin (TcB) meters, which employ a non-invasive approach by measuring light transmission through the skin.

Objective: The objective of this research is to conduct a comparative analysis between transcutaneous bilirubin levels in neonates and their corresponding total blood bilirubin levels.

Method: A cross- sectional study was conducted over the course of six months in the neonatal unit at Bahria International Hospital in Lahore. Systematic random sampling was used to recruit a total of 100 instances of newborn jaundice. Babies' demographic information was collected after they were born. The transcutaneous bilirubinometer (TCB) JM-105 was used to measure their bilirubin levels. Bilirubin levels in the serum were measured and documented simultaneously. The results of the two tests were compared to determine the degree of correlation between them.

Results: Out of 100 neonates, 61(61%) were male. For all weight ranges mean TCB values significantly correlated with mean serum bilirubin level (p<0.001) with correlation coefficient 0.778.

Conclusion: In newborns, total serum bilirubin (TSB) levels are highly associated with transcutaneous bilirubin (TcB) levels. Therefore, TcB can be utilized to direct care for these infants.
FREQUENCY AND SEVERITY OF IRON DEFICIENCY ANEMIA IN FEMALES OF CHILDBEARING AGE
Authors: Ahmad Nazia , Gondal Ayesha , Hafiza Fajar Shabbir  , Fateen Tooba , Rizwan Muhammad
Published: April 2024

Background: Anemia is a condition which develops either due to decrease in the number of red blood cells or low hemoglobin concentration. Hemoglobin is oxygen transport protein in red blood cells. Young children, anorexic teenagers, females of reproductive age group, pregnant females and malnourished females are at greater risk of developing anemia.

Objectives: The objective of this study was to find out the frequency and severity of anemias in child bearing females. 

Methods: This descriptive retrospective study was conducted in Ghurki Trust Teaching hospital Lahore from January 2022 to December 2023. Total of 2000 females of child bearing age, who ranged between 20-40 years were included. First group had ranged of age between 21 to 30 years whereas the second had ranged of age between 31 to 40 years. Data were entered and analysis by using SPSS version 22.

Results: Out of a total of 2000 cases, 713 (35.6%) had a normal hemoglobin level, whereas 1,287 (64.35%) had a decreased hemoglobin level. In present study, we found 41.05% females with mild, 18.6% cases of moderate anemia, whereas only 4.75% cases presented with severe degree of anemia.

Conclusion: Females presenting with symptoms of fatigue, tiredness and palpitations, anemia should be considered as one of the causes of this presentation of anemia.
ANTI-NOCICEPTIVE OUTCOMES OF ANTICONVULSANT/ANTIDEPRESSANT MEDICINES IN THE MANAGEMENT OF FORMALIN INDUCED PAIN IN GROUP OF MICE
Authors: Sidra Shah  , Ayesha Shaukat
Published: April 2024

Background: Anti-depressant are used to treat various disorders like neuropathic pain, migraine etc. Anticonvulsant drugs may have a role in the modulation of changes include inhibition of voltage gated ion channels at sites of spinal, supraspinal and peripheral.

Objectives: An experimental observational study was carried out to find the role of anti-nociceptive outcomes of anticonvulsant/antidepressant medicines in the management of formalin induced pain in group of mice.

Methods: A total of 20 albino mice weighed 20-30 gm. were taken from animal dwelling of The University of Lahore. Formalin induced pain was judged by observing the lifting of paw and behavior. Animals were divided in 4 groups (five mice in each group) group no 1: Control, group no 2: Paracetamol, group no 3: Fluvoxamine, group no 4: Lamotrigine.  After given the doses of drugs, 5.0 % formalin solution was injected. Number of counts of licking paw and paw-lifting of mice during first phase and second phase was noted. Percentage effectiveness was calculated by the formula.

The palliative action of the medicine was evaluated by calculating the latency moment in reaction to stimulus of heat. The animals were positioned on hot plate at time interval zero min, 30 min, 60 min and 90 min subsequent the administration of medicine. The Latency time until animal began either jumping or licking was noted. Percentage of maximum possible effects (MPE) is calculated by formula.

Conclusion: Our study shows the anti-nociceptive outcomes of fluvoxamine & lamotrigine in the management of formalin induced pain in group of mice
Nursing care in autologous hematopoietic progenitor transplantation
Authors: Cedeño Toapanta Alison Paulina , Chileno Camacho Luis Felipe
Published: April 2024

Background: Autologous hematopoietic progenitor transplantation (auto-HPT) is a treatment for hematologic diseases that involves infusion of the patient's hematopoietic stem cells. It requires prior myeloablative conditioning and specialized care. The procedure, potential complications, and nursing care at different stages were described. Methods: Systematic review using the PRISMA approach, with inclusion and exclusion criteria. The search was performed in multiple databases in English, Spanish, and Portuguese, between 2019 and 2023. Twenty full articles that met the criteria were analyzed. Results: The most commonly used source of hematopoietic progenitors at present is peripheral blood. Before infusion, the patient receives conditioning with high-dose chemotherapy. The main complication is infections; overall survival at 5 years is 68-80%. Nursing care in auto-HPCT is indispensable in all its stages because it performs preventive care, patient education, nutritional and emotional support, management of complications, and subsequent reintegration. Conclusion: Specialized and timely nursing care, based on the available evidence, allows improving the results and reducing the complications associated with auto-HPT, impacting the survival and quality of life of these patients.
Estudos e aspectos gerais do cipó-insulina (Cissus sicyoides / Verticillata)
Authors: Silva Cianny Ximenes Rodrigues , Belfort Marcia Guelma Santos , Azevedo Suellen Alves de
Published: April 2024

As plantas medicinais sempre estiveram presentes no dia a dia das comunidades brasileiras, sendo utilizadas seja para culinária, ou fins medicinais. Ao abordar acerca de plantas com poder hipoglicemiantes, o Cipó-Insulina é utilizado pela população para auxiliar no controle da insulina, além de auxiliar em patologias que envolvem o sistema renal, gastrointestinais, entre outros. É evidente durante a leitura a existência de dezenas de estudos com a planta, entretanto, observa-se também pouco acervo em comparação a outras plantas, buscou-se, portanto, realizar a comparação e descrição das pesquisas existentes acerca da espécie. O uso do Cipó-insulina em pesquisas, sejam in vivo ou in vitro, são produzidos os extratos vegetais da planta, geralmente das folhas. Na literatura buscada, descrita na metodologia, os maiores quantitativos de literaturas encontradas são do tipo trabalho de conclusão de curso, monografia, dissertação, artigos publicados em revistas e sites online. Em que buscou-se realizar um aparato geral sobre o uso do cipó insulina no controle da diabetes, pesquisas com seres humanos, in vitro e in vivo existentes., além de abordar os aspectos gerais da planta, como os aspectos agronômicos, químicos, farmacológicos, etnobotânicos , morfológicos e distribuição geográfica.
Tópicos de genética médica voltados para a atenção primária à saúde
Authors: Grangeiro Carlos Henrique Paiva
Published: April 2024

A Genética Médica é uma especialidade reconhecida pelo Conselho Federal de Medicina (CFM) desde 1983 e, em 1986, foi fundada a Sociedade Brasileira de Genética Médica e Genômica (SBGM). O médico geneticista realiza avaliação clínica, diagnóstico, tratamento e aconselhamento genético de indivíduos e de famílias com condições genéticas, assim como suporte e consultoria para outras especialidades e demais profissionais da saúde. Além disso, esse profissional tem assumido um papel fundamental no cuidado das pessoas com doenças raras, uma vez que 80% delas têm causa genética. Ressalta-se que a grande maioria dos médicos brasileiros não recebeu formação em Genética Médica, antigamente descrita como Genética Clínica, uma vez que a grande maioria dos cursos de medicina tem na sua grade curricular apenas a disciplina de genética básica/biologia molecular. Além disso, os avanços da medicina genômica têm permitido maior acesso aos exames genéticos, incremento diagnóstico e, por conseguinte, maior responsabilidade dos profissionais na solicitação e interpretação desses exames. Por tudo isso, foram elaborados capítulos, na forma de tópicos, com os principais temas de Genética Médica fundamentais para o médico da atenção primária, já que eles compõem a primeira porta de acesso ao SUS. Esses capítulos foram escritos, na sua maioria, por alunos do curso de medicina, participantes de ligas acadêmicas, que tiveram contato com a prática da Genética Médica.
DESAFIOS E PERSPECTIVAS NA GESTÃO DA FIBROSE PULMONAR IDIOPÁTICA: RUMO A TERAPIAS MAIS EFICAZES
Authors: Silva Aurélia Samila , Bomfim Vitória Vilas Boas da Silva , Brito Ingri Rochael Aguiar Xisto , Bucciaroni Rafael Karakhanian , Oliveira Paula Mendes Ribeiro e , Bezerra Breno Willams Wanderley , Costa Lídia Mirella Marques , Rios Neto Het Jones
Published: April 2024

A fibrose pulmonar idiopática (FPI) é uma doença pulmonar intersticial progressiva e fatal, caracterizada por fibrose e remodelação dos pulmões. Esta revisão aborda os desafios e perspectivas na gestão da FPI, com foco na identificação de estratégias terapêuticas mais eficazes. Os desafios incluem o diagnóstico precoce, a heterogeneidade da doença e a falta de tratamentos curativos. As perspectivas futuras destacam a importância da abordagem multidisciplinar, da personalização do tratamento, do investimento em pesquisa translacional e da exploração de novos alvos terapêuticos. Apesar dos avanços recentes, a gestão da FPI continua sendo um desafio clínico significativo, e são necessárias abordagens inovadoras para melhorar os resultados clínicos e a qualidade de vida dos pacientes.
أبعاد هندسة العوامل البشرية وعلاقتها بالتوافق الاستراتيجي بجامعة حائل
Authors:   أستاذ مشارك، كلية التربية، جامعة حائل، المملكة العربية السعودية, الثويني يوسف
Published: April 2024

هدفت الدارسة إلى التعرف على أبعاد هندسة العوامل البشرية وعلاقتها بالتوافق الاستراتيجي بجامعة حائل وذلك لتقديم مجموعة من المقترحات التي يمكن أن تسهم في تحقيق التوافق الاستراتيجي بجامعة حائل من خلال تطبيق أبعاد الهندسة البشرية بها، ولتحقيق هذا الهدف فقد استخدم الباحث المنهج الوصفي، واستفاد من استخدام هذا المنهج في جمع البيانات والمعلومات وتحليلها وتفسيرها، والتعرف على آراء اعضاء هيئة التدريس حول واقع كل من الهندسة البشرية والتوافق الاستراتيجي ومن ثم الخروج بمجموعة من المقترحات التي يمكن أن تسهم في تحقيق التوافق الاستراتيجي بجامعة حائل من خلال تطبيق أبعاد الهندسة البشرية بها، وقد اسفر البحث عن وجود علاقة ارتباطية بين أحد أبعاد الهندسة البشرية وأبعاد التوافق الاستراتيجي المتمثلة في (الاتصالات، والحوكمة، والشراكة، البنى التحتية) لدى أعضاء هيئة التدريس بجامعة حائل، ومن خلال ما توصل إليه البحث فقد أوصى الباحث بزيادة الاهتمام بتطبيق أبعاد الهندسة البشرية بجامعة حائل، لتحسين بيئة العمل بها، بحيث تكون أكثر راحة وأمانًا؛ وذلك رغبةً في زيادة التوافق الاستراتيجي؛ ومن ثم زيادة قدرتها على استقطاب العناصر المميزة من أعضاء هيئة التدريس بالإضافة إلى تحقيق رؤيتها ورسالتها الاستراتيجية، وكذلك تهيئة كافة المستلزمات الأساسية للعمل الجامعي من كراسي ومناضد وأدوات ومعدات وفق القياسات التي تتلاءم مع طبيعة جسم الإنسان، وبما لا يؤدي إلى التعب والإجهاد.
تحليل محتوى توليدات ChatGPT فيما يتعلق بالقضية الفلسطينية بشكل عام والتعليم بشكل خاص
Authors:   طالبة دكتوراه في التعلم والتعليم، كلية العلوم التربوية وإعداد المعلمين، جامعة النجاح الوطنية، نابلس، فلسطين, عمر أمل , الزبيدي جمال ,   طالب دكتوراه في التعلم والتعليم، كلية العلوم التربوية وإعداد المعلمين، جامعة النجاح الوطنية، نابلس، فلسطين, براهمة دعاء ,   طالبة دكتوراه في التعلم والتعليم، كلية العلوم التربوية وإعداد المعلمين، جامعة النجاح الوطنية، نابلس، فلسطين, فريحات طلال ,   طالب دكتوراه في التعلم والتعليم، كلية العلوم التربوية وإعداد المعلمين، جامعة النجاح الوطنية، نابلس، فلسطين, عفونة سائدة ,   أستاذ مشارك، كلية العلوم التربوية وإعداد المعلمين، جامعة النجاح الوطنية، نابلس، فلسطين
Published: April 2024

هدف البحث إلى تحليل وتقييم محتوى التوليدات التي يقدمها ChatGPT حول فلسطين والقضية الفلسطينية والتعليم في فلسطين، والتعرف على مدى قدرة هذه التقنيات على توفير تحليلات دقيقة وجدلية في سياقات تتعلق بفلسطين والقضية الفلسطينية، كما يتناول البحث فهم كيفية معالجة ChatGPT للمعلومات المقدمة للمهتمين، مع التركيز على دقة وعمق الردود التي يقدمها. تم اعتماد البحث النوعي بأسلوب تحليل المحتوى النوعي للاستجابات التي قدمها ChatGPT، حيث قام الباحثون بتوجيه ثلاثة أسئلة أساسية موحدة - وبنفس الصياغة لبرنامج ChatGPT حول فلسطين والقضية الفلسطينية والتعليم فيها - بثلاث محاولات بأوقات مختلفة، حيث تم بتوجيه الأسئلة الثلاث لبرنامج ChatGPT ثلاث مرات بأوقات مختلفة لأربع مرات، بهذه الطريقة حصلوا على 36 استجابة لكل موضوع 12 إجابة. وأظهرت نتائج الدراسة: أن ChatGPT قدم استجابات حول التعليم في فلسطين وفي كثير من الجوانب التي تخص القضية الفلسطينية كأصل الصراع وسبب النكبة وغيرها، كما أن ChatGPT تغافل بعض الجوانب المهمة في التعليم والقضية الفلسطينية كالتعليم في القدس وفي مناطق الداخل المحتل عام 1948، كما تغافل قضية الأسرى والمعتقلين وأهمية القدس بالنسبة للعرب والمسلمين، ومن أهم النتائج أيضاً الانحياز الواضح لصالح إسرائيل في القضايا السياسية والتاريخية والجغرافية المتعلقة بفلسطين وقضية القدس، وملكية الأراضي وأسباب وتداعيات الصراع الإسرائيلي الفلسطيني وفي غيرها من القضايا، وقد أوصى الباحثون بضرورة التحقق من مصداقية المعلومات من خلال مصادر موثوقة قبل الاعتماد عليها، خاصة في المواضيع ذات الأهمية كالتعليم في فلسطين والقضية الفلسطينية.
دور المعلمين في تنمية مهارات التفكير الإبداعي لدى طلبة المدارس الفلسطينية من وجهة نظر المعلمين أنفسهم (دراسة على عينة من المعلمين في محافظة بيت لحم)
Authors:   أستاذ علم الاجتماع وباحث في مجال العلوم الاجتماعية، رام الله، فلسطين, علاونة عبد المجيد
Published: April 2024

لقد تمثلت أهداف هذا البحث في العمل على تحديد الطرق التي يقوم بها المعلمون من أجل تنمية مهارات التفكير الإبداعي لدى الطلبة في داخل المجتمع العربي الفلسطيني، وتمثل مجتمع هذا البحث بجميع المعلمين العاملين والمسجلين ضمن وزارة التربية والتعليم الفلسطينية في احدى المحافظات الفلسطينية وهي محافظة بيت لحم في جنوب فلسطين المحتلة، وقد تم أخذ عينة هذا البحث بقيمة وصلت الى (154) من فئة المعلمين في محافظة بيت لحم الفلسطينية في العام (2023م)، وقد تم استخدام "أداة الاستبانة" كأداة رئيسية واساسية ميدانية في هذا البحث. أما فيما يتعلق بالنتائج النهائية والاستنتاجية لهذا البحث فقد تبين أنه يوجد علاقة قوية وذات دلالة إحصائية ما بين العوامل الخاصة بالطرق المستخدمة من قبل المعلمين والقائمة على تشجيع طرق التفكير الإبداعي وتعزيز وجودها وما بين العوامل الخاصة بمدى التحسن الذي طرأ على الطلبة من جراء استخدام طرق التفكير الإبداعي المحفزة على هذا الإبداع من قبل المعلمين، وهذا يعني أن الطرق المستخدمة من قبل المعلمين والقائمة على تشجيع طرق التفكير الإبداعي وتعزيز وجودها لها تأثير كبير وواضح ومهم ومؤثر على مدى التحسن الذي طرأ على الطلبة من جراء استخدام طرق التفكير الإبداعي المحفزة على هذا الإبداع من قبل المعلمين، وقد تم وضع عدد من التوصيات في نهاية هذا البحث كان منها: ضرورة العمل على استمرار الاستخدام لطرق التفكير الإبداعي من قبل فئة المعلمين وتوسيعها في كافة محافظات المجتمع الفلسطيني وعدم اقتصارها على عدد من المدارس او المحافظات الفلسطينية فقط.
Convective Drying of Turmeric Rhizome
Authors: Santosh Gagare  , V. D. Mudgal  , P.S. Champawat
Published: April 2024

Experimental trials on convective drying of turmeric (Curcuma longa L) rhizomes were conducted using factorial completely randomized design. Turmeric rhizome samples were cured for 30 min in 0.1 % solution of sodium carbonate and dried in a laboratory tray dryer at air temperatures of 50 °C, 60 °C and 70 °C with drying air velocity of 2 m.s-1. Drying air temperature was optimized on the basis of maximum retention of curcumin content, and b value of colour with minimum drying time and specific energy consumption. Optimization of drying parameters was carried out using numerical optimization technique. The optimum temperature for convective drying of turmeric rhizomes was found to be 60 °C with drying time of 29 hours.
Performance Evaluation of Tractor Operated Rotary Assisted Broad Bed Former-cum-seeder for Wheat Sowing
Authors: K. P. Saha  , Dushyant Singh  , Dilip Jat  , K. P. Singh
Published: April 2024

Tillage practices influence the soil physical parameters, which consequently affect the yield of a crop and provide solution against environmental hazards. A study was undertaken to comprehend the effects of broad bed former-cum-seeder on crop parameters, grain and biomass yield, cost-economics and energetics of operation. Simultaneous operation of tractor operated rotary-assisted broad bed former-cumseeder, developed at ICAR-Central Institute of Agricultural Engineering, was compared with sequential operation of conventional seed drill on broad beds and rotary tilling on flatbed in black cotton soil for wheat cultivation. Though higher germination of seeds (183 per m2 ) was observed with simultaneous operation of bed making and seeding by rotary-assisted broad bed former-cum-seeder, but the differences in yield among treatments were insignificant. The input energy requirement in first crop year (17,710 MJ.ha-1) was marginally higher than that in conventional method (17,445 MJ.ha-1). It decreased by 378 MJ.ha-1 compared to conventional system in the second crop year. The lowest average cost of operation (2607 ` ha-1) in simultaneous operation of bed forming and seeding in the first year, followed by maintaining permanent beds in subsequent years led to an additional income of 13,980 ` ha-1 over farmers’ practice. Rotary-assisted broad bed formercum-seeder thus has the potential to boost the income of the farmers and better energy management.
Development of Extruded Snacks Using Maize, Soy, Apple Pomace - A Response Surface Methodology Approach
Authors: Shahzad Faisal  , Indra Mani  , Ram Kishor Gupta  , Mridula D  , Sunil Kumar Jha  , Baljit Singh
Published: April 2024

Response surface methodology (RSM) using a D-optimal mixture design was employed for optimisation of formulation for production of a maize-soy-apple pomace based extruded snack. Effects of ingredients levels as maize (50–70 %), defatted soy flour (10–30 %) and apple pomace (10–30 %) on the physical properties like bulk density, expansion ratio, colour, water absorption index and water solubility index, sensory and specific mechanical energy of snacks were investigated. Significant regression equations that explained the effects of different percentages of maize, soy and apple pomace on all response variables were determined. The coefficients of determination, R2 , of all response variables were higher than 0.90. Adequate precision for developed model of all responses was higher than 9.0, and corresponding CV was less than 1.9 per cent. Based on the given criteria for optimisation, the basic formulation for production of maize-soy-apple pomace extruded snack with desired sensory quality was obtained by incorporating with 70.0 % maize, 14.57 % soy and 15.43 % apple pomace.
Engineering Properties of Rice-bean Varieties from North-East India
Authors: Rejaul Hoque Bepary  , D. D. Wadikar  , P. E. Patki
Published: April 2024

Rice-bean (Vignaumbellata) is a non-conventional, under utilized and multipurpose crop of South and South-East Asia. Eleven rice-bean varieties were studied for their colour, bean area, bean volume, sphericity, bulk density, true density, porosity, angle of repose, static coefficient of friction, and thermal transitions. Beans of variety JCR-08-10 had dark (L: 20.96±1.00), trifling red (a: 0.42±0.1) and minute blue (b: -0.69 ± 0.13) in colour. The length, width and thickness of all varieties ranged from 6.52 - 8.44 mm, 3.87 - 5.28 mm and 3.14 - 4.35 mm, respectively. The sphericity, bean volume and bean surface area of these varieties were between 63.02 - 69.9 %, 30.94 - 70.92 mm3 , and 51.09 - 87.73 mm2 , respectively. The thousand-bean mass, bulk density, true density, porosity, angle of repose of rice-bean varieties were 57.64 - 118.72 g, 820 – 877 kg.m-3, 1138.40 – 1388.79 kg.m-3, 26.47 – 40.57 %, 9.57-21.40º, respectively. The varieties JCR-08-8, JCR-08-12, JCR-08- 15 had comparatively higher bulk density than other varieties. The static coefficients of friction for glass, stainless steel and aluminium were 0.29 - 0.37, 0.38 - 0.45, and 0.35 - 0.55, respectively. Differential scanning calorimetry thermograms revealed that JCR08-8, JCR-08-12 and JCR-50 had highest melting temperature ranging between 121.73 o C and 155.45 o C.
Sorption Study on Developed Low-cost Solid Desiccant Material for Solar Dryer
Authors: Arun Kumar Attkan  , Nitesh  , Y. K. Yadav
Published: April 2024

A study was attempted to develop a solar regenerative Bentonite - CaCl2 based solid desiccant material, and examine it's moisture sorption performance and regeneration characteristics. The desiccant was developed from 60 % bentonite, 20 % vermiculite, 10 % CaCl2 and 10 % cement. Regeneration studies on the desiccant were carried out for moisture adsorption at 30 °C and 96 % R.H. for 144 h; and moisture desorption at 40 °C, 50 °C, 60 °C, 70 °C and 80 °C for 8 h. Regeneration temperature and time significantly affected the moisture sorption and desorption of the solid desiccant, and their combined impact was meaningful (p ≤ 0.05). Maximum adsorption capacity of the desiccant was 35.12 % (d.b.), and was efficiently regenerated by solar energy
Textural and Sensory Characteristics of Hot Air-dried Tofu
Authors: S. M. Chavan  , R. C. Verma  , G. P. Sharma
Published: April 2024

Some rehydration, textural and sensory characteristics of tofu dried at 45°C, 60°C and 75°C were studied. Rehydration ratio and coefficient of rehydration were found to vary from 1.39 to 1.49, and 0.67 to 0.93, respectively. Hardness and adhesiveness were found to decrease from 5077.34 g to 3939.95 g and (-) 4.47 to (-)39.71g.s, while springiness and chewiness increased from 0.14 to 0.22 and 647.60 to 820.77, respectively, with increase in drying temperature. L values increased with temperature from 48.04 to 53.55. Sensory characteristics of tofu dried at 75°C obtained from a consumer panel showed acceptability of the product.
Development of Low-cost Detachable Roof Greenhouse for Round the Year Cultivation of Tomato and Capsicum
Authors: Pramod Rai
Published: April 2024

Greenhouse is a well-established technology for crop cultivation or nursery growing under controlled, or partially controlled, condition. The major hindrance in its widespread adoption is construction cost and environment management. A low-cost detachable roof greenhouse was developed for round-the-year cultivation of tomato/capsicum. The temperature under the greenhouse during winter season (November-February) was 1-3 0 C higher than at open field condition due to greenhouse effect. The temperature during summer season (March-June) in the greenhouse was between 5-46 0 C, and was lower than the temperature (6-49 0 C) under open field condition. During rainy season (July-October), the temperature recorded were 9-38 0 C and 12-41 0 C, respectively, under greenhouse and open field condition. The light intensity and relative humidity in the greenhouse varied between 0.7-53.2 klux and 14-96 %, respectively.
Performance Evaluation of IARI Wheat Seed-cum-Fertilizer Plot Drill for Pearl Millet-Wheat Cropping System on Permanent Raised Bed System
Authors: Chetan Kumar P. Sawant  , Adarsh Kumar  , Indra Mani  , J. K. Singh  , Rajbir Yadav  , R. N. Sahoo
Published: April 2024

A four-row IARI seed-cum-fertilizer plot drill developed at ICAR-IARI, New Delhi for permanent raised bed system was evaluated under pearl millet-wheat cropping system. The machine was fitted with two Oyjord metering mechanisms with four outlets for metering seed and fertilizer. Successful seeding on raised beds with pearl millet crop residue was achieved by first cutting the plant residue with a plain disc coulter, followed by seed drilling in narrow slit furrows opened by double disk furrow openers. The plot drill required 33.56 kW tractor for its operation in sandy loam soils, and two operators to feed measured quantity of seed and fertilizer. Field capacity of the plot drill was 0.17 ha.h-1 at 1.5 km.h-1 forward speed of operation. Field machine index, field efficiency and cost of operation were 72.72, 80 % and ` 648/- per hour, respectively. The plant stands of wheat sown on permanent raised beds with the developed plot drill were significantly higher than with precision plot drill.