bluuebunny/crossref_metadata_2025 huggingface dataset:
Maternal Serum Alpha Feto Protein Level May Predict Morbidly Adherent Placenta in Women with Placenta Previa
Authors:   Azadi Teaching Hospital, Kirkuk, Iraq, Hassan Sarah , Ghalib Ayla ,   of Obstetrics and Gynecology, College of Medicine, Kirkuk University, Kirkuk, Iraq
Published: September 2023

Background: In situations of a morbidly adherent placenta, studies have shown that maternal serum alfa feto protein (AFP) is clinically high. Objective: To examine the association of morbidly adherent placenta (MAP) in pregnant women with placenta previa (PP) and their serum AFP biomarker. Methods: A prospective observational study that was conducted in the Department of Obstetrics and Gynecology at Azadi Teaching Hospital, Kirkuk, Iraq during the period from Feb. till Nov. 2019. It included 82 pregnant women those between 14-20 weeks of gestation with singleton pregnancy, viable fetus, and diagnosed with low lying placenta, with and without vaginal bleeding. A blood sample from all women was taken to investigate for serum AFP level after confirming the diagnosis of low-lying placenta by early abdominal ultrasound (U/S) scan. All the enrolled pregnant women were followed by Doppler U/S at gestational age 28-32 weeks, underwent targeted screening for MAP and were divided into two groups according to the status of placenta: MAP group included 11 pregnant women and PP group alone included 71 pregnant women. Results: In this study, MAP was diagnosed in 13.4% of cases. Mean of serum AFP biomarker in women with MAP was significantly higher than that in women with PP. Serum AFP biomarker in early pregnancy >200 ng/ml is predictive for diagnosis of MAP in late pregnancy. Conclusion: Maternal serum AFP biomarker may play an important role at early pregnancy in prediction of placental adherence at late pregnancy in cases of early low-lying placenta. Keywords: Morbidly adherent placenta, alpha feto protein, previa, pregnancy, Iraq Citation: Hassan SS, Ghalib AK. Maternal serum alpha feto protein level may predict morbidly adherent placenta in women with placenta previa. Iraqi JMS. 2022; 20(2): 278-285. doi: 10.22578/IJMS.20.2.16
Hepatitis B Virus Genotypes and Pre-core and Core Genes Mutations in a Sample of Iraqi Patients with Chronic Hepatitis B Infection
Authors:   Division of Biotechnology, Dept. of Applied Sciences, University of Technology, Baghdad, Iraq, Hussain Hiba , Al-Shuwaikh Arwa M. ,   of Microbiology, College of Medicine, Al-Nahrain University, Baghdad, Iraq, Ahmed Abbas ,   Central Public Health Laboratory, Baghdad, Iraq
Published: September 2023

Background: Genomic studies of hepatitis B virus (HBV) diversity are becoming increasingly significant to understand how HBV mutations interact with a wide spectrum of clinical and pathological disorders. Objective: This study focused on identifying HBV genotypes and determining the status of pre-core (PC) and core promoter (CP) mutants. Methods: Nested polymerase chain reaction was used to identify the viral genotypes of 100 patients with chronic HBV infection. Only 30 samples out of 100 were selected to determine the prevalence of mutations in the PC and CP by Sanger sequencing. Results: Over 95% of the samples had only D genotype and mixed genotypes 5% (B+C+D) in chronic hepatitis B (CHB) patients. G1898A, G1901A, G1910A and G1915A mutations in PC gene were found in total 15 out of 30 (50%) samples, which were distributed in the following proportions: 12 out of 25 (48%) in patients with hepatitis B e antigen (HBeAg) -ve, 8 samples with mutants at G1898A, G1901A, G1910A and G1915A (four mutations), 4 samples with mutants at G1898A, G 1901A and G1910A (three mutations). In addition, 3 out of 5 (60%) in patients with HBeAg +ve, while no type of any mutation was detected in the core gene in patients with chronic hepatitis type B. Conclusion: The genotype D was predominantly prevalent among HBV in CHB patients with 95% and with 5% in mixed genotypes (B+C+D), while genotype B and C were relatively less prevalent among CHB patients than genotype D. The mutations were found in the PC gene at nucleotides G1898A, G1901A, G1910A and G1915A, while no type of mutation was detected in the core gene. Keywords: Genotypes, pre-core mutation, core mutation, HBV Citation: Hussain HT, Al-Shuwaikh AM, Ahmed AM. Hepatitis B virus genotypes and pre-core and core genes mutations in a sample of Iraqi patients with chronic hepatitis B Infection. Iraqi JMS. 2022; 20(2): 217-225. doi: 10.22578/IJMS.20.2.8
Teoria democrática
Authors: Pires Pierre André Garcia , Verçosa Pelegrino Santos , Dantas Andréa Maria Lopes
Published: September 2023

O presente artigo apresenta a concepção de democracia, discutindo sua origem e trajetória até a contemporaneidade. A democracia é entendida como uma forma de governo que possibilita não apenas a tomada de decisões, mas também a elaboração de regras e discussões coletivas envolvendo os representantes eleitos pelo povo, com a participação ativa desses representantes nas decisões e na prevenção de um regime autocrático. São destacados dois tipos de democracia: a democracia direta, na qual a participação em massa ocorre sem a presença de representantes nas discussões e tomadas de decisão, e a democracia representativa, na qual o povo elege seus representantes para decidirem questões que dizem respeito à coletividade. Também são ressaltadas algumas características e limitações da democracia. A democracia pressupõe como ponto central o estabelecimento de regras, uma vez que, sem regras em um processo democrático, a democracia não pode existir ou sobreviver, pelo menos no que se refere ao processo de tomada de decisões e participação.
The effects of online learning about the Brønsted-Lowry theory of acids and bases in the first grade of grammar school during the COVID-19 pandemic
Authors: Holik Ana-Andrea , Trivic Dragica
Published: September 2023

The aim of this paper was to examine the effects of the application of online material on the Br?nsted-Lowry theory of acids and bases on the active construction of knowledge in first-grade grammar school students during the COVID-19 pandemic. The online material was designed to enable students: a) to learn the teaching material in smaller parts; b) to assess the acquired knowledge after each part of the teaching material; c) to progress through the lesson at their own pace; d) to visualise and interrelate the macroscopic, submicroscopic and symbolic representations of the contents about acids and bases by using a video recording and illustrations; e) to re-examine the accuracy of the given answers. The research sample consisted of 122 first-grade grammar school students, who learnt about the Br?nsted?Lowry theory for the first time. The instruments used in this research study were two tests (a pre-test and a post-test), the validity of which was examined by two university professors and two grammar school chemistry teachers. The applied approach enabled the active construction of knowledge in the majority of students, while it provided the teachers with an insight into the progress and outcomes of the process.
The criminal offense of counterfeiting money in France from the revolution to the end of the 19th century
Authors: Marinkovic Milica
Published: September 2023

Introduction. General anesthesia is frequently employed in neck surgery
procedures. However, in patients at high risk for general anesthesia,
regional anesthesia options, such as the superficial cervical plexus block,
warrant careful consideration. Patients with mediastinal lymph node
enlargement face an elevated risk of airway obstruction and hemodynamic
mediastinal instability during anesthesia induction. In selected neck
surgeries, including thyroglossal cyst excision, thyroglossal fistula
repair, bronchial cyst removal, thyroidectomy, and lymph node excision, the
superficial cervical plexus block presents a viable and secure alternative
to general anesthesia. Case report. This report details the case of a
patient with mediastinal lymphadenopathy and multiple brain metastases who
underwent cervical lymph node excision. Given the patient?s severe
comorbidities, pronounced risk of complete distal airway obstruction,
hemodynamic instability, and the potential for compression effects from
mediastinal mass, a superficial cervical block was administered. This block
facilitated effective perioperative analgesia without inducing respiratory
or cardiovascular instability. Conclusion. The superficial cervical plexus
block emerges as a prudent alternative to general anesthesia in high-risk
patients necessitating cervical lymph node excision procedures. Its
utilization should be considered in such cases to enhance patient safety and
perioperative management.
Demographic changes in the total number and ethnic structure of the population of Sirinic zupa from 1913 to 2011
Authors: Medojevic Jovo , Milosavljevic Sasa
Published: September 2023

The geographical area of Sirinic zupa is a part of the region of the
Autonomous Province of Kosovo and Metohija. The subject of studying the
total number and ethnic structure of the population is based on the
monitoring and analysis of demographic processes and their trends in Sirinic
zupa from 1913 to 2011. With 16 settlements, Zupa represents a multi-ethnic
area where Serbs, Albanians, Gorans, Muslims, Bosniaks and Roma have lived
for centuries. As a separate parish, this region was first mentioned in the
era of the Serbian medieval state. During the period of Turkish rule, and
even later until the 19th century, settlements and economic life in Sirinic
zupa stagnated. Sirinic zupa was included in the population censuses from
1913 to 2011. The population censuses from 1921 and 1931 clearly indicate an
increase in the population. After the Second World War, Sirinic zupa was
included in the censuses from 1948 to 2011. Censuses in the period from 1948
to 1989 record a constant increase in the population. However, the 1991
census recorded a decrease in the total number of inhabitants by 1% compared
to the 1989 census. Demographic processes after 1999, when NATO bombed FR
Yugoslavia and AP Kosovo and Metohija, unequivocally point to complex and
serious factors that befell the Serbian community. The 2011 census, which
was organized by the temporary institutions of Kosovo and Metohija, was
boycotted by the Serbian population. Today, Serbs live in enclaves,
displaced, without human dignity, without jobs and without conditions for
returning to their centuries-old Serbian hearths. The current demographic
processes in Sirinic zupa are characterized by the complexity identified
through the reduction of the population, unfavourable security conditions
for the Serbian community, unfavourable economic, health and social
development.
The media and violence - cyberbullying
Authors: Milenkovic Vesna
Published: September 2023

Violence in the media mostly refers to the use of explicit scenes of violence
seen on film and television screens as well as in the cyberspace of
interactive digital games. Everlasting questioning about the negative
effects of the media of mass communication was especially evident in the
time of expansion of television and the ?narcotic role? of the television
image, when violence became one of the most commercial areas from which the
media got the topics of their cultural content. The arrival of the new ways
of communication by means of digital media has opened another page in the
consideration of the notion of violence in the media - cyberbullying.
Therefore, the subject of the paper is violence in the media and the
possible effects of traditional and social media on the global audience. By
presenting some of the theoretical considerations and empirical research on
the effects of the media, the aim of this paper is to answer the question of
how much the connection there is between the media and violence with special
reference to digital abuse as a long-term exposure to violence on social
networks. By using the descriptive-explanatory method and the method of
theoretical analysis, by connecting theoretical knowledge and empirical
data, the paper, within the scope of the research, presents the overview of
theoretical premises related to the action of violence in the media.
Likewise, the examples from the field of the effects of violence in
traditional and digital media were reviewed in order to realize the
phenomenon of violence and its connection with the media. The research
results indicated the connection between the effects of traditional and
digital violence and the particular danger of different methods of
cyberbullying considering the characteristics of this phenomenon. Beginning
with the assertion that the media greately influences the recipients with
their aggressive content, by applying a literature review, the models of
aggression in the traditional media were pointed out, as well as the methods
by which cyberbullyingis done by means of text or video messages that
insult, harass, threaten. The answer to the question of the connection
between the media and violence required theoretical reflections and the
presentation of empirical research in order to realize the effects of
violent communication, and especially to shed light on digital abuse on
social networks. Recent analyses of cyberbullyingrarely rely on the previous
research and do not tend to connect mutually in order to provide a general
picture, so it is difficult to get a whole picture of the state of violent
content in digital media. Nevertheless, even though there are opinions about
the media as being the sole culprits of violence in society, even though
completely opposite opinions are pointed out, the latest researches
unequivocally prove that the theory about the ineffectiveness of media
violence is not sustainable.
Charles J. Hirsch, Controller, Golden Nugget Casino: Rolling the Dice on Statistical Sampling and Analysis
Authors: Boylan Scott J.
Published: September 2023

Charles J. Hirsch was an accountant and controller for the Golden Nugget casino from 1950 to 1970. He contributed to a movement in the 1950s and 1960s to advance the use of statistical sampling and analysis in the accounting profession. This manuscript is based on analysis of Hirsch’s professional papers, held at the University of Nevada, Las Vegas, Libraries Special Collections and Archives. Hirsch used statistical sampling and analysis at Golden Nugget when statistical techniques had not yet been widely accepted or implemented by practicing accountants and auditors. Beginning in 1959, Hirsch made numerous conference presentations describing his work. In addition, Hirsch explicitly challenged the accounting profession to follow his lead and integrate statistical sampling and analysis into existing practice. In doing so, he joined an exclusive group of individuals, including Robert Trueblood, who were early advocates for using statistical techniques to improve the practice of accounting and auditing.
Do Adverse Opinions on Internal Control over Financial Reporting Lead to Changes in Reporting Format?
Authors: Strawser Jerry R.
Published: September 2023

SYNOPSIS

This study examines whether the format of audit reports on financial statements and internal control over financial reporting (ICFR) changes in response to the disclosure of one or more material weaknesses in ICFR. The results indicate that (1) reporting format changes are more likely when adverse opinions are issued on ICFR and (2) formats are more likely to change from a combined report to separate reports than vice versa. Supplemental analysis reveals that format changes to separate reports do not result in more favorable market perceptions but do result in marginally lower levels of auditor dismissal/change. These findings indicate that auditors have incentives to acquiesce to client requests to change reporting formats, even though such changes do not result in more favorable market perceptions.

Data Availability: Data are available from public resources noted in the text.

JEL Classifications: M41; M42.
Diversity at Work: Firms’ Strategic Responses to Mandatory Diversity Disclosure
Authors: Oelrich Sebastian , Siebold Nicole , Ketelhut Klemens
Published: September 2023

SYNOPSIS

Diversity has emerged as a topic of increasing organizational and legislative relevance. Despite forming a burgeoning research field in accounting, little is known about how organizations respond to diversity disclosure legislation. In this paper, we study the introduction of diversity disclosure legislation in the European Union that mandates corporate diversity disclosures, and we analyze how 30 large German companies disclose diversity in their annual reports. Drawing on institutional theory and Oliver’s (1991) seminal work on strategic responses to institutional processes, our analysis reveals four mandatory reporting responses: dismissal, concealment, imitation, and transcendence. Overall, our findings show that although diversity has been institutionalized into organizational environments by the European Union through legislative action, organizational responses vary, from resistance to passive conformity or proactive compliance. With these findings, our study adds to the emergent diversity accounting literature, and we conclude by highlighting implications of our work for policymakers, managers, and researchers.

Data Availability: Data are available from the public sources cited in the text.
Men’s Experiences of Paternity Leaves in Accounting Firms
Authors: Garnier Claire , Mangen Claudine , Nortier Edwige
Published: September 2023

SYNOPSIS

Accounting researchers and practitioners have made strides in addressing persistent gender inequalities in the accounting profession. However, these efforts have largely sidestepped men and masculinities. Our study considers the role of men and masculinities in gender inequalities by exploring how men in accounting experience paternity leaves. We conduct interviews with 13 men in audit firms in France. We find that fathers are reluctant to take leaves, which they view as vacation periods incompatible with their professional work. They see audit firms as offering less support to fathers than mothers, with support for fathers growing but still marginal. Finally, they experience a variety of emotions, including positive emotions around fatherhood and negative emotions around difficulties in reconciling fatherhood with professional responsibilities and paternity leaves. Practically, our findings imply that to address gender inequalities further, accounting firms need to change the norms around care work, including paternity leaves.
Use of artificial intelligence large language models as a clinical tool in rehabilitation medicine: a comparative test case
Authors: Zhang Liang , Tashiro Syoichi , Mukaino Masahiko , Yamada Shin
Published: September 2023

Objective: To explore the potential use of artificial intelligence language models in formulating rehabilitation prescriptions and International Classification of Functioning, Disability and Health (ICF) codes. 
Design: Comparative study based on a single case report compared to standard answers from a textbook.
Subjects: A stroke case from textbook. 
Methods: Chat Generative Pre-Trained Transformer-4 (ChatGPT-4)was used to generate comprehensive medical and rehabilitation prescription information and ICF codes pertaining to the stroke case. This information was compared with standard answers from textbook, and 2 licensed Physical Medicine and Rehabilitation (PMR) clinicians reviewed the artificial intelligence recommendations for further discussion.
Results: ChatGPT-4 effectively formulated rehabilitation prescriptions and ICF codes for a typical stroke case, together with a rationale to support its recommendations. This information was generated in seconds. Compared with standard answers, the large language model generated broader and more general prescriptions in terms of medical problems and management plans, rehabilitation problems and management plans, as well as rehabilitation goals. It also demonstrated the ability to propose specified approaches for each rehabilitation therapy. The language model made an error regarding the ICF category for the stroke case, but no mistakes were identified in the ICF codes assigned. 
Conclusion: This test case suggests that artificial intelligence language models have potential use in facilitating clinical practice and education in the field of rehabilitation medicine.
Lokalprojekte – innovatives Projektmanagement und Sinnstiftung
Authors: Büchner Katja , Bock Charlotte
Published: September 2023

Die meisten Menschen streben in ihrem beruflichen Alltag nach einem Sinn. Sie wollen ihre praktischen Erfahrungen und ihr Wissen in die Organisation einbringen. Gleiches gilt für den öffentlichen Sektor. Das gemeinnützige Unternehmen Lokalprojekte (LP) bietet nun eine innovative Möglichkeit, fachlich qualifizierte Personen aus Wirtschaft und Gesellschaft mit Kommunen und Behörden über die gemeinsame Arbeit an sinnstiftenden Projekten zusammenzubringen. Welcher Weg zur Gründung von Lokalprojekte geführt hat, wie sich die Idee von Lokalprojekten zu einer eigenen Methode des Projektmanagements entwickelt hat und welche Perspektiven sich aus den ersten Praxiserfahrungen und Projekten für die kommunale Verwaltung ergeben, davon berichtet dieser Artikel.
„Lessons Learned“ aus „Best Practices“ greift zu kurz – warum Lernen im Projekt anders gestaltet werden muss
Authors: Wagenhals Klaus , Hansemann Henrik
Published: September 2023

Wir kennen alle die Projektauswertungen auf den letzten Drücker – oft zum Ende des Projekts nach einem problematischen Ritual und oft mit einem Team, das sich in Auflösung befindet oder schon neue Projekte im Kopf hat. Nun war die Hoffnung – nicht zuletzt wegen der anderen Vorgehensweise, der größeren Transparenz, der stärkeren Veränderungs-Orientierung – dass im agilen Projektgeschäft besser, schneller, wirkungsvoller gelernt wird. Nach einigen Jahren Erfahrung und vielen Studien, die nachweisen, dass das nur zum Teil der Fall ist, sind wir klüger. Was läuft also schief? Wie kann das im agilen Konzept angelegte, organisationale Lernen (Senge, 1990) genutzt, „entfesselt“ weiterentwickelt werden? Wir zeigen, wie das vorhandene Potenzial für anders Lernen durch Nutzung eines modernen Lern-Begriffs und die Stärkung der Selbstorganisation gehoben werden kann.
Dabei sein ist alles
Authors: Köhler Jens
Published: September 2023

Die Kolumne „Ehrlich und Priesberg“ möchte mit unterhaltsamen Dialogen rund um das Thema „Mensch – Kommunikation, Verhalten, Entscheidungen“ Denkanstöße für den PM-Alltag geben.
Évaluation, à l’aide de séries chronologiques interrompues, de l’effet de la légalisation du cannabis sur les lésions auto-infligées dans deux provinces canadiennes : Ontario et Alberta
Authors: Cusimano Michael D. , Carpino Melissa , Walker Madison , Saarela Olli , Mann Robert
Published: September 2023

Introduction

Malgré l’association connue entre consommation de cannabis et prévalence accrue d’idées suicidaires et de tentatives de suicide, on n’a pas encore mesuré l’effet de la légalisation et de la réglementation du cannabis au Canada sur les lésions auto-infligées.

Méthodologie

Nous avons utilisé des séries chronologiques interrompues des taux de consultation aux urgences et d’hospitalisation pour lésions auto-infligées pour 100 000 habitants en Ontario et en Alberta entre janvier ou avril 2010 et février 2020. Les effectifs mensuels globaux de consultations aux urgences et d’hospitalisations pour lésions auto-infligées (codes X60-X84 et R45.8 selon la CIM-10) ont été obtenus grâce respectivement au Système national d’information sur les soins ambulatoires et à la Base de données sur les congés des patients.

Résultats

La légalisation et la réglementation du cannabis au Canada n’ont pas été associées de manière statistiquement significative à une modification des taux de consultation aux urgences pour lésions auto-infligées en Ontario (niveau = 0,58 avec IC à 95 % : −1,14 à 2,31; tendance = −0,17 avec IC à 95 % : −0,35 à 0,01) ou en Alberta (niveau = −0,06 avec IC à 95 % : −2,25 à 2,12; tendance = −0,07 avec IC à 95 % : −0,27 à 0,13). Les hospitalisations pour lésions auto-infligées sont également demeurées inchangées en Ontario (niveau = −0,14 avec IC à 95 % : −0,48 à 0,20; tendance = 0,01 avec IC à 95 % : −0,03 à 0,04) et en Alberta (niveau = −0,41 avec IC à 95 % : −1,03 à 0,21; tendance = −0,03 avec IC à 95 % : −0,08 à 0,03).

Conclusion

La légalisation et la réglementation du cannabis au Canada n’ont pas entraîné d’augmentation des taux de consultation aux urgences ou d’hospitalisation pour lésions auto-infligées en Ontario ou en Alberta. Des analyses à l’échelle individuelle tenant compte des caractéristiques individuelles et incluant d’autres provinces et territoires sont nécessaires.
Vision system for monitoring process of winding cylindrical products with a carbon bundle
Authors: Сарамуд Михаил , Спирин Евгений , Талай Евгений , Пикалов Яков
Published: September 2023

The problem of control of a correct laying of carbon bundle on a mandrel is considered. A mandrel in the form of a cylindrical pipe is considered in the article. Software has been developed for automated analysis of controlled parameters (distances between points). The

results obtained are preliminary and can be improved by: optimizing the camera position and lighting; taking into account camera distortion parameters; formation of a development of the surface of the sharpening with bundles.
Don Salvino Sierra y el Instituto Anatómico de Valladolid
Authors: Vaquero Puerta Carlos , San Norberto Enrique , García Rivera Elena , Diez Manuel , Hernández Cristian
Published: September 2023

La Facultad de Medicina de Valladolid, seis veces centenaria ha contado siempre con unos prestigiosos estudios en anatomía desde su fundación. Sin embargo, en los inicios del siglo XX se produce en la Facultad de Medicina de Valladolid un desarrollo espectacular en estos estudios de la mano del catedrático de Anatomía don Salvino Sierra y Val que logra obtener los recursos para crear una de las instituciones más prestigiosas de la universidad vallisoletana proporcionando medios, dependencias y profesores, que elevaron a un rango de alto nivel científico y docente los estudios de Anatomía. Se analiza en el trabajo la creación del Instituto Anatómico que llevaría posteriormente el nombre de su fundador y la figura del Profesor Salvino Sierra.
Tratamiento de cicatrices con toxina botulínica: grado de evidencia científica
Authors: Alonso Arroyo Verónica , Barnes Marañón Sarah , Forero Torres Alexander , Granell Suarez Cristina , Jiménez Crespo Victoria
Published: September 2023

Las cicatrices queloides representan el mayor grado de inestetismo del espectro de la hipertrofia de la cicatriz y constituyen un verdadero desafío clínico.  Se han descrito numerosas estrategias terapéuticas dirigidas a este tipo de cicatrices, como cirugía, láser, radiofrecuencia e infiltración, entre otras.  No obstante, el enfoque terapéutico ideal no ha sido alcanzado hasta el momento.

Recientemente, se ha publicado el empleo de la Toxina Botulínica tipo A (BoNT-A) como parte del tratamiento de las cicatrices queloides con resultados controvertidos. Se presenta una revisión de la evidencia científica de los estudios que comparaban el empleo de la BoNT-A con el uso de corticoides intralesionales, así como el mecanismo de acción y los efectos secundarios de la misma.

Los resultados de las revisiones sistemáticas para la prevención y/o tratamiento de la cicatrización hipertrófica o queloidea con BoNT-A, no muestran una evidencia científica consistente.  Además, es complicado obtener datos concluyentes debido al pequeño tamaño de las cohortes, la dificultad para extrapolar los resultados de la experimentación animal a la población general y a la heterogeneidad existente en los diferentes estudios.

La evidencia científica considera que es posible realizar un uso "off- label” de la BoNT-A puesto que es eficaz y segura como tratamiento para prevenir o mejorar las cicatrices inestéticas. Por otro lado, a pesar de que los corticoides podrían ser superiores a la BoNT-A en algunos aspectos, parece que los efectos secundarios asociados a su uso podrían evitarse con el uso de la toxina botulínica.
REVITALIZATION OF THE EARTH'S ALMS TRADITION WITH ISLAMIC RITUALS IN THE DIGITAL ERA
Authors: Malik Muh Syauqi , Maulida Arina Zulva , Maslahah Maslahah
Published: September 2023

Earth almsgiving is a tradition that has existed since the time of the ancestors in Indonesia. The tradition of the ancestors is a form of gratitude to God Almighty for the abundance of his grace in a certain region. Society must be able to distinguish between expressions of gratitude and destruction.  This type of research is a qualitative case study in a certain society to thoroughly explore the benefits and meaningfulness of the essence of the earth's alms tradition that still needs to be maintained in the digital era. Data analysis techniques use data reduction, data presentation, conclusion drawing, and verification.  The results showed that the earth alms tradition has a very strong Islamic philosophy and ritual, people must understand the essence of earth alms as a whole so as not to just follow the currents of the times. The factor that makes people want to hold the earth alms tradition is a form of gratitude for the abundance of grace from God Almighty. The tradition of earth almsgiving is not shirked nor is it to satisfy the lust of entertainment by holding a momentary feast, but must stick to Islamic rituals according to the sharia of the Prophet Muhammad SAW and the teachings of the saints along with the guidance of religious leaders in the region
Escrever sensações, inscrever afectos: notas para uma teoria literária menor segundo Gilles Deleuze
Authors: Nogueira Caio Vinícius Russo
Published: September 2023

A literatura não se esgota nos seus aspectos discursivos, o que significa dizer que há algo mais, um afecto, um conjunto de afectos e perceptos que passa por entre as palavras sem, contudo, se diluir nelas. Embora não exista sem a linguagem (quid facti), a literatura produz sensações diferenciais (quid juris) que ultrapassam a lógica discursiva e a veiculação dos enunciados. Para além do imperativo comunicacional, as personagens e as paisagens da literatura podem ser descritas enquanto insistências virtuais, o que, nem por isso, as tornam, no entanto, menos reais. A literatura, ou o fato literário, torna sensível o insensível da linguagem enquanto violência que torna sensória os limites mesmos da nossa sensibilidade. É a partir dessas proposições de Gilles Deleuze que este ensaio se debruça, procurando explicitar o uso de uma constelação de conceitos que insiste na capacidade da literatura de escrever sensações, de inscrever afectos. “Devir”, “Território” e “Ritornelo” são alguns desses conceitos que servem de orientação para a hipótese de uma teoria literária menor que procura cartografar os afectos produzidos pela literatura. Essa teoria literária menor poderia ser denominada, de igual modo, uma estética da literatura.
Msaho e a proposta de renovação da linguagem literária
Authors: Deus Lílian Paula Serra e
Published: September 2023

Ao lançar o olhar sobre o movimento Msaho, que surge em Moçambique no ano de 1952, intenta-se demonstrar como a língua portuguesa, entendida inicialmente como língua do colonizador, abarcou as tensões do período, assumindo-as no campo da literatura. Para além disso, objetiva-se demonstrar como os autores pertencentes a esse movimento literário, como, por exemplo, José Craveirinha, Noémia de Sousa e Virgílio de Lemos, fortaleceram o processo de africanização da língua portuguesa, permitindo que, na construção literária, pudessem ecoar as vozes de diferentes etnias e dos costumes celebrados por elas.
Tatuagens complicadas do meu peito: Camilo Pessanha, um artífice do ideograma
Authors: Marchioro Camila
Published: September 2023

Este artigo tem por objetivo analisar algumas composições de Clepsydra, 1920, de Camilo Pessanha, e estabelecer uma comparação entre sua obra e a escrita chinesa. Portanto, atenta-se para a qualidade visual da poesia de Pessanha e para o modo como leu, traduziu e trouxe aspectos da poesia chinesa para os seus versos. Promove-se, ainda, um diálogo entre o poeta coimbrão e a tradição poética chinesa, recuperando alguns importantes nomes em diversas épocas. Mostra-se, ainda, como Camilo Pessanha foi pioneiro no uso de temas provenientes da poesia oriental em sua escrita, antecipando elementos do imagismo. Desse modo, o artigo revela Pessanha, ao lado de Ezra Pound, como um precursor da incorporação da estética do ideograma na literatura do Ocidente. Ainda, comenta-se sobre a atividade tradutora do poeta, que age pela hospitalidade da língua, conforme Derrida, e de forma vampiresca ao usar a diferença a seu favor e trazê-la como parte da sua prática artística. Por fim, objetiva-se mostrar como a aprendizagem e a tradução de ideogramas alimentaram a poética de Camilo Pessanha e constituem questão central tanto de sua ética quanto de sua estética.
Guimarães Rosa ou o homem intuitivo nietzschiano
Authors: Beretta Laysa
Published: September 2023

Considerando a imensa capacidade de criação linguística observada nas obras rosianas e os estudos publicados desde a década de 1950 sobre os aspectos formais do texto, percorri, no presente estudo, alguns neologismos cunhados por Guimarães Rosa (1956) em Grande sertão: veredas à luz do ensaio “Verdade e mentira no sentido extra-moral” (1873), de Nietzsche. Assim, pretendi observar a construção e, sobretudo, a função do universo linguístico erigido no romance. Quero dizer: o que vale a palavra na obra de Guimarães Rosa? Qual é o valor da verdade enquanto conceito? A palavra rosiana confina um valor? E se confina, o que os neologismos pretendem confinar?
Cronotopo e realidade objetiva em Os ratos, de Dyonélio Machado
Authors: Borges Luiz Paixão Lima
Published: September 2023

Tendo como base conceitual o caráter histórico e social do cronotopo bakhtiniano, categoria artístico-literária que confirma a presença de realidade na obra, o presente artigo propõe uma análise materialista e dialética do romance Os ratos (1935), de Dyonélio Machado (1895-1985). O artigo apoia-se, também, na teoria marxista que trata do par dialético alienação e consciência, na busca de se compreender o comportamento do personagem Naziazeno frente às pressões econômicas e sociais do capitalismo, compreendendo que o tempo e o espaço, artisticamente configurados, determinam o seu comportamento, emprestando a ele não apenas as marcas externas de sua época, mas todo um complexo de atitudes que definem as relações sociais a que está subordinado.
Apalutamide in the treatment of non-metastatic castration-resistant prostate cancer in an elderly patient with multiple comorbidities
Authors: Liśkiewicz Katarzyna
Published: September 2023

Prostate cancer has been the most common malignant tumor in men in Poland since 2016 and is the second cause of death in this group of patients. The basic method of treatment in patients with advanced prostate cancer is androgen deprivation therapy, however, over time, the tumor evolves into a castration-resistant form, which poses a significant threat to the patient's life. This article presents a case of an elderly patient with internal diseases, who in the castration-resistant stage, was treated with a new generation androgen receptor blocker – apalutamide – in the first line of systemic treatment.
Apalutamide in the treatment of a patient with non-metastatic castration-resistant prostate cancer
Authors: Dziura Robert
Published: September 2023

The treatment of patients with prostate cancer, who do not qualify for the radical therapy is based on the use of surgical or pharmacological castration methods. The effectiveness of the so-called androgen deprivation tends to decrease over time. Even in the absence of distant metastases on imaging studies, the resistance for the hormonal castration may be developed. At this moment, the use of new generation androgen receptor inhibitors may reduce the risk of metastases or death. The paper presents a case report of a patient with prostate cancer without distant metastases who started therapy with apalutamide at the moment of developing re-sistance to the pharmacological castration.
The role of E2F2 in signaling pathways associated with cancer pathogenesis and potential treatment: A review of current studies
Authors: - - , Poboży Kamil , - - , - - , - - , - -
Published: September 2023

Introduction and objective. E2F transcription factor 2 (E2F2) protein is the transcription factor that plays an important role in tumorigenesis. E2F2 effects the cell cycle, tumor suppressor proteins, and can also be transformed by proteins of small DNA tumor viruses. The objective of the study is to provide a summary of the current knowledge on the neoplastic pathways that involve E2F2.

State of knowledge. Numerous studies have demonstrated a role for E2F2 in various signaling pathways. Certain components of these pathways may serve as potential targets for oncological therapy. E2F2 has been shown to be associated with neoplasms of various locations and histological types (breast, colon, gastric, laryngeal, liver, lung, ovarian, pancreatic, and prostate cancers).

Conclusions. Further investigations of E2F2 pathways are warranted for a clearer understanding of neoplastic processes and to identify novel pharmacological treatments.
Perforated Punctal Plugs for the Management of Acquired External Punctal Stenosis
Authors: Chamernik Alan , Różycka Katarzyna , Bakalarski Krystian , Różycki Radosław
Published: September 2023

The study presents the results of treating patients with pathological tearing caused by acquired external punctal stenosis.

Method: 61 eyes of 34 individuals with an average age of 67 were enrolled in the study. A perforated silicone implants were inserted into the narrowed lacrimal punctums, after pathological tearing had been diagnosed using the Munk test, fluorescein disappearance test, and other parameters. Implants has been removed after 3 months.

Results: Overall, a statistically significant (p < 0.001%) reduction in the fluorescein disappearance test was observed in 93.2% of eyes (n = 55). None of the patients experienced an exacerbation of excessive tearing. The average score on the fluorescein disappearance test decreased from 3.64 before the procedure to 1.42 after the procedure.

Conclusions: Intubation of the lacrimal punctum with perforated silicone implants is a quick, effective, and safe method for treating pathological tearing in cases of acquired narrowing of the lacrimal punctum.
Sjögren’s syndrome – diagnosis and contemporary therapeutic possibilities
Authors: Cwalina Oliwia , Pandey Ada , Prokop Dominika , Czarnacka Kinga , Gawlak Małgorzata , Kuźlik Bartosz , Guzek Katarzyna , Alsoubie Ismael , Chmura-Hołyst Alicja , Roszkowska Anna , Pawlicka Ilona , Piskorz Agnieszka , Kozak Maciej
Published: September 2023

Dry eye syndrome is a group of medical conditions that can be caused by many factors, as a result of which there is an abnormality in moisturizing of the eye surface by a tear film. One of the causes of this disorder is Sjögren’s syndrome, which is an autoimmune disease in which the body produces antibodies against its own proteins. The glands of external secretion, mainly lacrimal and salivary glands are damaged as a result of inflammation. Associated with this side effects, affect negatively and reduce the quality of life, which is why in the following article we present the available therapeutic options for patients suffering from ophthalmological manifestations of Sjögren’s syndrome.
Profilaktyka zakażeń po operacji zaćmy: fluorochinolony i leki przeciwzapalne – pojedynczo czy w preparatach złożonych?
Authors: Izdebska Justyna , Wróblewska Marta , Piechal Agnieszka , Misiuk-Hojło Marta
Published: September 2023

Operacja zaćmy jest jedną z najczęściej wykonywanych procedur medycznych. Obecnie najczęściej stosowanymi lekami przeciwbakteryjnymi po zabiegach okulistycznych są moksyfloksacyna i lewofloksacyna. Spośród steroidowych leków o działaniu przeciwzapalnym powszechnie wykorzystuje się etabonian loteprednolu lub fosforan deksametazonu. Ze względu na to, że obecnie obowiązujące wytyczne po operacji zaćmy zalecają różne czasy stosowania fluorochinolonów (1–2 tygodnie) i glikokortykosteroidów (3–4 tygodnie), to wydaje się uzasadnione podawanie tych leków w oddzielnych preparatach obecnie dostępnych na rynku. Istnieje bowiem obawa, że stosowanie preparatów złożonych może spowodować zbyt długie przyjmowanie przez pacjenta fluorochinolonu, by utrzymane zostało przeciwzapalne działanie glikokortykosteroidów w miejscu operowanym, to zaś może doprowadzić do selekcji szczepów opornych i zwiększa ryzyko działań niepożądanych.
Zastosowanie nowoczesnych soczewek monofokalnych „plus” w leczeniu operacyjnym zaćmy
Authors: Markuszewski Bartłomiej , Ziółkowska Sabina , Markuszewska Anna , Wylęgała Edward
Published: September 2023

Soczewki monofokalne „plus” pozwalają na większą niezależność od korekcji okularowej niż soczewki jednoogniskowe. Badania wykazały dobrą funkcję wzroku pacjentów na prawie wszystkie odległości oraz minimalną obecność niepożądanych artefaktów optycznych w ustawieniu refrakcji pooperacyjnej na obustronną emmetropię oraz na monowizję. W pracy opisano przypadki zastosowania soczewek monofokalnych „plus” w ustawieniu monowizji.
Auf schiefer Bahn - Politische Essays zur Zukunft
Authors: Kaeser Eduard
Published: September 2023

Es steht schlimm und schlimmer: um das Erdklima, die Tierarten, die Demokratie, die Menschenrechte, den Liberalismus, die Wahrheit, die Tatsachen und so fort. Fast von selbst stellt sich das Bild der schiefen Bahn ein, auf der wir nur abwärts rutschen. Menetekeln hat Konjunktur. Die gegenwärtige Lage der Krisen, Kriege, Katastrophen macht uns geneigt, zu denken, wir rutschten notwendig «abwärts». Seit der Corona-Pandemie übertrumpfen sich Auguren im Modus «Die nächste Katastrophe kommt bestimmt». Gegen diesen Abwärts-Determinismus richtet sich dieses Buch. «It ain’t necessarily so» – der Titel des Gershwin-Songs – beschreibt treffend die geistige Haltung der Essays: Denk nochmal darüber nach, vielleicht ist die Lage doch nicht so schlecht!
La sirena, un mito pluricultural y sincrético: exploraciones en la narrativa oral en América Latina
Authors: Martínez Reyes Fernanda María
Published: September 2023

Este artículo hace un pequeño recorrido por la tradición oral y la cultura popular en torno al personaje mítico de la sirena en América Latina. Se presenta una serie de leyendas, creencias populares y otros etnotextos de diferentes regiones del continente americano que nos revelan los orígenes, los modos de actuar, el papel que desempeñan, sistema de valores y normas de la conducta, pero también los peligros que se corre al enfrentarse con una de ellas. Este pequeño corpus permite apreciar las sorprendentes similitudes con la tradición universal y revela que estamos frente a un mito pluricultural y sincrético.
The Mermaid, a Pluricultural and Syncretic Myth: Explorations in Latin American Oral Narrative
Abstract
This article aims to provide an overview of the oral tradition and popular culture surrounding the mythical character of “La Sirena”, in Latin America. The article presents a series of legends, popular beliefs and other ethnotexts from different regions of the American continent that reveal the origins, the ways of acting, the role they play, the system of values, norms of conduct, as well as the dangers that one can face when confronted by a “Sirena”. The small corpus gathered in this article highlights the surprising similarities with the universal tradition and reveals that we are in front of a pluricultural and syncretic myth.
Recibido: 6 de marzo de 2023
Dictaminado: 10 de junio de 2023
Aceptado: 03 de julio de 2023
Transformaciones punitivas o voluntarias: personajes convertidos en piedra
Authors: Chajón Aníbal
Published: September 2023

Este artículo presenta la recopilación de tradición oral sobre monumentos, en siete ciudades de Guatemala, que ofrecen dificultades para preservar la moral tradicional católica, como el recato femenino, puesto que exhiben desnudez. La interpretación que se dio fue la de un castigo divino por sus pecados. El objetivo fue el de documentar la tradición oral relacionada con esos monumentos, que han generado interpretaciones colectivas sobre su significado, y determinar sus posibles orígenes históricos. Este objetivo se alcanzó plenamente a través del rastreo histórico de los monumentos, a la vez que se confirma que se trata de mensajes admonitorios: comportarse adecuadamente para no ser convertidos en piedra, como ejemplo del castigo divino.
Punitive or Voluntary Transformations: Characters Turned to Stone
Abstract
This article presents the compilation of oral tradition on monuments, in seven Guatemalan cities. Those monuments offer difficulties to preserve traditional Catholic morality, such as feminine modesty, since they display nudity. The popular interpretation was that of a divine punishment for their sins. The objective was to document oral tradition related to these monuments, which have generated collective interpretations of their meaning, and to determine their possible historical origins. This objective was fully achieved through the historical tracking of the monuments, while confirming that they are warning messages: behave appropriately or to be turned to stone, as an example of divine punishment.
Recibido: 20 de febrero de 2023
Dictaminado: 11 de julio de 2023
Aceptado: 28 de julio de 2023
Toledo: la cuna de la memoria e historia única
Authors: Sevin Tugba
Published: September 2023

Toledo, aunque se conoce por ser una ciudad de encuentro y convivencia de culturas diferentes, tiene también un lugar especial en la historia judía, porque se conoce como la capital judía de España. Este ensayo se enfoca en la Toledo judía y hace un repaso por los períodos que cubren la convivencia, la expulsión y la vida de los judeoespañoles después del exilio en 1492. Durante este recorrido histórico, será posible también analizar varias obras literarias que reflejan la imagen de los judíos y conversos en Toledo y en la Península en general.
Toledo: The Cradle of Memory and Unique History
Abstract
Toledo is known for being a city of encounter and coexistence of different cultures, but it also is a special place in the Jewish history, because it is known as the Jewish capital of Spain. This essay focuses on the Jewish Toledo and periods of the coexistence, the expulsion, and the life of the Judeo-Spaniards after the exile in 1492. Throughout this review it will also be possible to analyze various literary works that shed light on the image of the Jews and converts in Toledo and in the Peninsula.
Recibido: 26 de octubre de 2022
Dictaminado: 12 de diciembre de 2022
Aceptado: 9 de enero de 2023
Crónicas periodísticas del siglo XIX. Antología comentada
Authors: Hernández Suárez Diana
Published: September 2023

Miguel Ángel Castro (Ed.). (2023). Crónicas periodísticas del siglo XIX. Antología comentada. 552 pp. ISBN: 978-607-30-7619-7. Ciudad de México: Universidad Nacional Autónoma de México.
Para Susana Rotker, la crónica como género literario es el resultado de la hibridación de mecanismos y funciones textuales, una superación de la estética realista, pues no imita nada, no documenta, sino que “sobrepasa los esquemas” de lo concreto.
Desde las palabras del yo: estudios de escritura autobiográfica mexicana
Authors: Gómez García Arnoldo de Jesús
Published: September 2023

Horacio Molano Nucamendi, Claudia Gutiérrez Piña y Humberto Guerra (Coords.) (2022) Desde las palabras del yo: estudios de escritura autobiográfica mexicana. 270 pp. isbn: 978-607-30-6840-6. Ciudad de México: Universidad Nacional Autónoma de México.
Entre otros impulsos, y mediante distintas perspectivas, la labor de una antología de análisis literarios puede orientarse a perfilar problemas actuales o fenómenos poco tocados en el pasado.