bluuebunny/crossref_metadata_2025 huggingface dataset:
APOE ɛ4 Allele Moderates the Association Between Basal Forebrain Nuclei Volumes and Allocentric Navigation in Older Adults Without Dementia
Authors: Lerch Ondřej , Laczó Martina , Vyhnálek Martin , Nedelská Zuzana , Hort Jakub , Laczó Jan
Published: January 2022

Background: Cholinergic deficit and medial temporal lobe (MTL) atrophy are hallmarks of Alzheimer’s disease (AD) leading to early allocentric spatial navigation (aSN) impairment. APOE ɛ4 allele (E4) is a major genetic risk factor for late-onset AD and contributes to cholinergic dysfunction. Basal forebrain (BF) nuclei, the major source of acetylcholine, project into multiple brain regions and, along with MTL and prefrontal cortex (PFC), are involved in aSN processing. Objective: We aimed to determine different contributions of individual BF nuclei atrophy to aSN in E4 positive and E4 negative older adults without dementia and assess whether they operate on aSN through MTL and PFC or independently from these structures. Methods: 120 participants (60 E4 positive, 60 E4 negative) from the Czech Brain Aging Study underwent structural MRI and aSN testing in real-space arena setting. Hippocampal and BF nuclei volumes and entorhinal cortex and PFC thickness were obtained. Associations between brain regions involved in aSN were assessed using MANOVA and complex model of mutual relationships was built using structural equation modelling (SEM). Results: Path analysis based on SEM modeling revealed that BF Ch1-2, Ch4p, and Ch4ai nuclei volumes were indirectly associated with aSN performance through MTL (pch1 - 2 = 0.039; pch4p = 0.042) and PFC (pch4ai = 0.044). In the E4 negative group, aSN was indirectly associated with Ch1-2 nuclei volumes (p = 0.015), while in the E4 positive group, there was indirect effect of Ch4p nucleus (p = 0.035). Conclusion: Our findings suggest that in older adults without dementia, BF nuclei affect aSN processing indirectly, through MTL and PFC, and that APOE E4 moderates these associations.
A Proposed Brain-, Spine-, and Mental- Health Screening Methodology (NEUROSCREEN) for Healthcare Systems: Position of the Society for Brain Mapping and Therapeutics
Authors: Nami Mohammad , Thatcher Robert , Kashou Nasser , Lopes Dahabada , Lobo Maria , Bolanos Joe F. , Morris Kevin , Sadri Melody , Bustos Teshia , Sanchez Gilberto E. , Mohd-Yusof Alena , Fiallos John , Dye Justin , Guo Xiaofan , Peatfield Nicholas , Asiryan Milena , Mayuku-Dore Alero , Krakauskaite Solventa , Soler Ernesto Palmero , Cramer Steven C. , Besio Walter G. , Berenyi Antal , Tripathi Manjari , Hagedorn David , Ingemanson Morgan , Gombosev Marinela , Liker Mark , Salimpour Yousef , Mortazavi Martin , Braverman Eric , Prichep Leslie S. , Chopra Deepak , Eliashiv Dawn S. , Hariri Robert , Tiwari Ambooj , Green Ken , Cormier Jason , Hussain Namath , Tarhan Nevzat , Sipple Daniel , Roy Michael , Yu John S. , Filler Aaron , Chen Mike , Wheeler Chris , Ashford J. Wesson , Blum Kenneth , Zelinsky Deborah , Yamamoto Vicky , Kateb Babak
Published: January 2022

The COVID-19 pandemic has accelerated neurological, mental health disorders, and neurocognitive issues. However, there is a lack of inexpensive and efficient brain evaluation and screening systems. As a result, a considerable fraction of patients with neurocognitive or psychobehavioral predicaments either do not get timely diagnosed or fail to receive personalized treatment plans. This is especially true in the elderly populations, wherein only 16% of seniors say they receive regular cognitive evaluations. Therefore, there is a great need for development of an optimized clinical brain screening workflow methodology like what is already in existence for prostate and breast exams. Such a methodology should be designed to facilitate objective early detection and cost-effective treatment of such disorders. In this paper we have reviewed the existing clinical protocols, recent technological advances and suggested reliable clinical workflows for brain screening. Such protocols range from questionnaires and smartphone apps to multi-modality brain mapping and advanced imaging where applicable. To that end, the Society for Brain Mapping and Therapeutics (SBMT) proposes the Brain, Spine and Mental Health Screening (NEUROSCREEN) as a multi-faceted approach. Beside other assessment tools, NEUROSCREEN employs smartphone guided cognitive assessments and quantitative electroencephalography (qEEG) as well as potential genetic testing for cognitive decline risk as inexpensive and effective screening tools to facilitate objective diagnosis, monitor disease progression, and guide personalized treatment interventions. Operationalizing NEUROSCREEN is expected to result in reduced healthcare costs and improving quality of life at national and later, global scales.
Use of Telephone- and Internet-Based Support to Elicit and Address Financial Abuse and Mismanagement in Dementia: Experiences from the Care Ecosystem Study
Authors: Manivannan Madhumitha , Heunis Julia , Hooper Sarah M. , Bernstein Sideman Alissa , Lui Kristi P. , Braley Tamara L. , Possin Katherine L. , Chiong Winston
Published: January 2022

Background: Financial mismanagement and abuse in dementia have serious consequences for patients and their families. Vulnerability to these outcomes reflects both patient and contextual factors. Objective: Our study aimed to assess how multidisciplinary care coordination programs assist families in addressing psychosocial vulnerabilities and accessing needed resources. Methods: Our study was embedded in a clinical trial of the Care Ecosystem, a telephone- and internet-based supportive care intervention for patients with dementia and caregivers. This program is built around the role of the Care Team Navigator (CTN), an unlicensed dementia care guide who serves as the patient and caregiver’s primary point of contact, screening for common problems and providing support. We conducted a qualitative analysis of case summaries from a subset of 19 patient/caregiver dyads identified as having increased risk for financial mismanagement and abuse, to examine how Care Ecosystem staff identified vulnerabilities and provided support to patients and families. Results: CTNs elicited patient and caregiver needs using templated conversations to address common financial and legal planning issues in dementia. Sources of financial vulnerability included changes in patients’ behavior, caregiver burden, intrafamily tension, and confusion about resources to facilitate end-of-life planning. The Care Ecosystem staff’s rapport with their dyads helped them address these issues by providing emotional support, information on how to access financial, medical, and legal resources, and improving intra-familial communication. Conclusion: The Care Ecosystem offers a scalable way to address vulnerabilities to financial mismanagement and abuse in patients and caregivers through coordinated care by unlicensed care guides supported by a multidisciplinary team.
Zeaxanthin Attenuates the Vicious Circle Between Endoplasmic Reticulum Stress and Tau Phosphorylation: Involvement of GSK-3β Activation
Authors: Zhang Li-Na , Li Meng-Jie , Shang Ying-Hui , Liu Yun-Ru , Han-Chang Huang , Lao Feng-Xue
Published: January 2022

Background: Alzheimer’s disease (AD) characterized by neurofibrillary tangles caused by hyperphosphorylated tau is the most common cause of dementia. Zeaxanthin (Zea), derived from fruits and vegetables, may reduce the risk of AD. Endoplasmic reticulum stress (ERS) might cause memory impairment in AD. Objective: Here, we studied protective role of Zea on the relationship among ERS, activity of glycogen synthase kinase 3β (GSK-3β, tau phosphorylated kinase), and p-Tau (Ser 396 and Thr 231). Methods: The results were obtained in non-RA and RA group by using different treatment, such as 9-cis-retinoic acid (RA), TM (ERS inducer), Zea, 4-PBA (ERS inhibitor), and SB216763 (GSK-3β inhibitor). The methods included flow cytometry and MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] for the detections of cell cycle and cell viability and western blot as a third measure of proteins in relation to ERS and tau phosphorylation. We have collected and analyzed all the data that suggested application of drugs for the treatment in non-RA and RA group. Results: Zea displays its protection on TM-induced cell injury, upregulation of GRP78 expression, and change of GSK-3β activity and tau phosphorylation when 4-PBA and SB216763 interfere with the process. Conclusion: These studies indicated that Zea is in vicious circle in ERS, GSK-3β, and tau phosphorylation, and further reflect its potential value in AD.
TOPSIS method for spherical fuzzy MAGDM based on cumulative prospect theory and combined weights and its application to residential location
Authors: Zhang Huiyuan , Wei Guiwu , Wei Cun
Published: January 2022

Nowadays, how to choose a comfortable and relatively satisfactory residence is one of the multiple attribute group decision making (MAGDM) issues which people are paying more and more attention. However, since the inaccuracy and fuzziness of the information are given by decision makers (DMs) in practical decision-making and psychological factors of DMs should be considered in the decision-making process, this paper presents TOPSIS approach based on cumulative prospect theory (CPT) to deal with the MAGDM issues under the spherical fuzzy environment. Furthermore, considering the objective relationship between the attributes, the combined weights are used to get attribute weights in spherical fuzzy sets (SFSs). Finally, an example of residential location is introduced to prove the validity of our proposed approach by comparing with spherical fuzzy TOPSIS(SF-TOPSIS) method and spherical fuzzy WASPAS (SF-WASPAS) method.
Integrated optimization of production planning and scheduling in uncertain re-entrance environment for fixed-position assembly workshops
Authors: Jiang Nan-Yun , Yan Hong-Sen
Published: January 2022

For the fixed-position assembly workshop, the integrated optimization problem of production planning and scheduling in the uncertain re-entrance environment is studied. Based on the situation of aircraft assembly workshops, the characteristics of fixed-position assembly workshop with uncertain re-entrance are abstracted. As the re-entrance repetition obeys some type of probability distribution, the expected value is used to describe the repetition, and a bi-level stochastic expected value programming model of integrated production planning and scheduling is constructed. Recursive expressions for start time and completion time of assembly classes and teams are confirmed. And the relation between the decision variable in the lower-level model of scheduling and the overtime and earliness of assembly classes and teams in the upper-level model of production planning is identified. Addressing the characteristics of bi-level programming model, an alternate iteration method based on Improved Genetic Algorithm (AI-IGA) is proposed to solve the models. Elite Genetic Algorithm (EGA) is introduced for the upper-level model of production planning, and Genetic Simulated Annealing Algorithm based on Stochastic Simulation Technique (SS-GSAA) is developed for the lower-level model of scheduling. Results from our experiments demonstrate that the proposed method is feasible for production planning and optimization of the fixed-position assembly workshop with uncertain re-entrance. And algorithm comparison verifies the effectiveness of the proposed algorithm.
Proximal policy optimization with model-based methods
Authors: Li Shuailong , Zhang Wei , Zhang Huiwen , Zhang Xin , Leng Yuquan
Published: January 2022

Model-free reinforcement learning methods have successfully been applied to practical applications such as decision-making problems in Atari games. However, these methods have inherent shortcomings, such as a high variance and low sample efficiency. To improve the policy performance and sample efficiency of model-free reinforcement learning, we propose proximal policy optimization with model-based methods (PPOMM), a fusion method of both model-based and model-free reinforcement learning. PPOMM not only considers the information of past experience but also the prediction information of the future state. PPOMM adds the information of the next state to the objective function of the proximal policy optimization (PPO) algorithm through a model-based method. This method uses two components to optimize the policy: the error of PPO and the error of model-based reinforcement learning. We use the latter to optimize a latent transition model and predict the information of the next state. For most games, this method outperforms the state-of-the-art PPO algorithm when we evaluate across 49 Atari games in the Arcade Learning Environment (ALE). The experimental results show that PPOMM performs better or the same as the original algorithm in 33 games.
StackBC: Deep learning and transfer learning techniques based stacking approach for accurate Invasive Ductal Carcinoma classification using histology images
Authors: Ul Haq Amin , Li Jian Ping , Wali Samad , Ahmad Sultan , Ali Zafar , Khan Jalaluddin , Khan Ajab , Ali Amjad
Published: January 2022

Artificial intelligence (AI) based computer-aided diagnostic (CAD) systems can effectively diagnose critical disease. AI-based detection of breast cancer (BC) through images data is more efficient and accurate than professional radiologists. However, the existing AI-based BC diagnosis methods have complexity in low prediction accuracy and high computation time. Due to these reasons, medical professionals are not employing the current proposed techniques in E-Healthcare to effectively diagnose the BC. To diagnose the breast cancer effectively need to incorporate advanced AI techniques based methods in diagnosis process. In this work, we proposed a deep learning based diagnosis method (StackBC) to detect breast cancer in the early stage for effective treatment and recovery. In particular, we have incorporated deep learning models including Convolutional neural network (CNN), Long short term memory (LSTM), and Gated recurrent unit (GRU) for the classification of Invasive Ductal Carcinoma (IDC). Additionally, data augmentation and transfer learning techniques have been incorporated for data set balancing and for effective training the model. To further improve the predictive performance of model we used stacking technique. Among the three base classifiers (CNN, LSTM, GRU) the predictive performance of GRU are better as compared to individual model. The GRU is selected as a meta classifier to distinguish between Non-IDC and IDC breast images. The method Hold-Out has been incorporated and the data set is split into 90% and 10% for training and testing of the model, respectively. Model evaluation metrics have been computed for model performance evaluation. To analyze the efficacy of the model, we have used breast histology images data set. Our experimental results demonstrated that the proposed StackBC method achieved improved performance by gaining 99.02% accuracy and 100% area under the receiver operating characteristics curve (AUC-ROC) compared to state-of-the-art methods. Due to the high performance of the proposed method, we recommend it for early recognition of breast cancer in E-Healthcare.
Study on the extension evaluation of smart logistics distribution of fresh agricultural products based on the perspective of customers
Authors: Li Huipeng , Lu Lin , Yang Liguo
Published: January 2022

The rapid development of the Internet has accelerated the expansion of e-commerce sacle of fresh agricultural products. The actual audience of smart logistics distribution of fresh agricultural products is customers, and customers enjoy the process and results of distribution services. However, the current research mainly selects indicators from the aspects of enterprise performance, cost and technical level based on the perspective of managers and technicians, which make it difficult to truly reflect customers’ feelings in the evaluation results. At the same time, the evaluation methods mainly focus on the comprehensive evaluation method and fuzzy evaluation method. These evaluation methods are greatly affected by subjective factors in the evaluation grade distribution, and the assignment is often relatively complete and inaccurate. To solve these problems, this paper constructs the evaluation index system of intelligent logistics distribution of fresh agricultural products from the perspective of customers, so that the selection of indicators is more in line with the real wishes of customers. And we use the extension function to construct the correlation function for multi-level extension evaluation to ensure the accuracy of the evaluation results. Taking X logistics enterprise as an example, this paper verifies the scientificity of the evaluation index system of intelligent logistics distribution of fresh agricultural products through empirical research, which has reference significance for further improving the intelligent logistics distribution of fresh agricultural products.
Aquatic Therapy for Persons with Neuromuscular Diseases – A Scoping Review
Authors: Ogonowska-Slodownik Anna , de Lima Ana Angélica R. , Cordeiro Luciana , Morgulec-Adamowicz Natalia , Alonso-Fraile María , Güeita-Rodríguez Javier
Published: January 2022

Background: Aquatic exercise is among the most common physical activity modalities performed by people with disabilities. Objective: The present paper reviews currently-available research on aquatic therapy (AT) for persons with neuromuscular diseases (NMD). Methods: A scoping review of the existing literature was conducted on PubMed, Embase, Medline, Scopus, Web of Science, SPORTdiscus, CINAHL and Lilacs from the earliest date available until October 2020. It follows the methodological framework for conducting a scoping review proposed by the Joanna Briggs Institute. Results: A total of 28 articles were analyzed and the study parameters grouped by the topography of NMD; most of the studies (n = 16) addressed myopathies. A considerable increase in the number of studies was found over time, and heterogeneity was identified across and within AT interventions for persons with NMD; hence, to allow more effective interpretation of study results, there is a need to standardize the fundamental parameters and procedures for AT. Conclusions: This scoping review provides a comprehensive outline of available literature; the findings could serve as a starting point for clinical studies on the effects of AT on persons with NMD, and encourage a more coherent approach to their design.
Study of Fish Community in Ulak Lia Lake Sekayu, Musi Banyuasin Regency
Authors: Helmizuryani Helmizuryani , Sari Meika Puspita , Alpis Alpis , Khotimah Khusnul , Muslimin Boby
Published: January 2022

This study aims to determine fish's diversity, abundance, and dominance in Ulak Lia Lake, Sekayu District. This research was conducted at Lake Ulak Lia, Sekayu District, Musi Banyuasin Regency, from February to March 2021. The fish sampling method was performed by direct catching at three predetermined observation stations using nets. Netting was carried out for 12 hours, taking catches with traps that have been installed in the morning from 7 a.m. to 9 a.m., depending on conditions or weather. Sampling was marked using a bamboo buffer and the help of the Global Positioning System (GPS). The results showed that the Diversity Index ranged from 1.85 to 1.91 indicating low diversity. The fish abundance index ranged from 30.16 to 36.87 indicating low fish abundance. Where the Dominance Index 0.71-0.72 shows a moderate dominance index. Meanwhile, the dominant fish in Ulak Lia Lake is the Sapil fish (Helostoma temminckii).
Land taxation as a tool to ensure sustainable development of rural areas in the context of decentralization
Authors: Khomiuk N. , Tsymbaliuk I. , Voichuk M. , Grymak A. , Kravtsiv I.
Published: January 2022

The article considers land taxation as one of the tools to ensure the sustainable development of rural areas in the context of decentralization. Included land tax and rent for land plots of state and communal property and a single tax for agricultural producers as land tax payments has been proposed. It was found that the land fee is the second-largest source of tax revenues to local budgets. It was revealed that during 2009–2020 there is a tendency to increase revenues from land fees to local budgets of Ukraine. Emphasis is placed on the fact that there is an increase in rent payments by legal entities and individuals in parallel with a decrease in its share in the payment for land, which is caused by an increase in land tax revenues during the analyzed period by 4.5 times. It was found that the largest amounts of revenues from land fees are payments from legal entities (86–88 % of the total revenues). It was found that the number of revenues from land tax and rent for land plots of state and communal property paid by individuals increased 4.5 times, and the number of revenues from similar taxes from legal entities increased 3.6 times. As a result of the study, attention is focused on the fact that since 2015 the payment for land has been transferred from the status of a national tax to a local one. It is proved that to tax the regulation of agricultural land use and promotes the development of agriculture and rural areas in 1998, a fixed agricultural tax was introduced. It was found that the number of receipts of the single tax paid by agricultural producers in 2015 increased 17 times compared to 2014. The sharp increase is caused by the introduction of the annual indexation of the tax base for agricultural enterprises, and a threefold increase in tax rates is justified. To achieve the goals of sustainable development of rural areas, it is proposed to carry out such measures as the application of increasing coefficients for irrational use of agricultural lands, provision of benefits for organic agricultural producers, implementation of the full inventory of agricultural lands, improvement of normative monetary valuation of land use for land and/or the single tax of the fourth group for the implementation of measures for the protection and reproduction of land resources, which will increase employment in rural areas, overcome poverty, develop social infrastructure, ensure the livelihood of rural residents, food, economic and environmental security, reduce destructive effects on the environment, protection and reproduction of natural resource potential.
Efeito do biofeedback em tratamento fisioterapêutico no pós-operatório de pacientes com câncer de próstata: uma revisão integrativa
Authors: Gomes Mariana Ferreira , Souza Isabel Fernandes de , Martins Tatiane
Published: January 2022

Introdução. O Câncer de Próstata (CaP) ocupa, mundialmente, a segunda posição entre as neoplasias malignas que acometem os homens. A prostatectomia (PR) é um procedimento cirúrgico para tratamento do CaP, classificado em aberto ou laparoscópico. Os pacientes apresentam sintomas pós-operatórios, sendo os mais recorrentes a disfunção erétil (DE) e a incontinência urinaria (IU), ambos causados por lesões de feixes nervosos na cirurgia. Objetivo. Identificar evidências dos efeitos do uso do biofeedback no tratamento de sintomas pós-operatório de pacientes com CaP. Metodologia. Pesquisa teórica do tipo integrativa em publicações, de uma década, compreendida entre os anos de 2000-2019, abordando uso do biofeedback como tratamento para IU e DE. A pesquisa ocorreu no período de maio a junho de 2020. Foram recuperados 434 artigos nas bases Pubmed, PEDro, Lilacs, Scielo e J-Stage e 7 selecionados após aplicação dos critérios de inclusão/exclusão. Resultados. As pesquisas incluídas na revisão abordaram homens prostatectomizados que se submeteram aos protocolos de biofeedback eletromiográfico. Foi observado, que o uso do biofeedback para a IU e outras disfunções teve até 85,7% de relatos positivos. Considerações finais. A revisão teórica evidenciou que o biofeedback usado precocemente pode oferecer efeitos benéficos para a IU e até mesmo na potência sexual.
ВИКОРИСТАННЯ ТЕХНОЛОГІЇ «КРАВАТКА-МЕТЕЛИК» (BOWTIE) В ПРАКТИЦІ ОЦІНКИ РИЗИКІВ
Authors: Нечаєва Ірина , Дончик Дар’я
Published: January 2022

Кожне підприємство має правові, економічні та етичні цілі, які варіюються від забезпечення обов’язкової безпеки до комерційних цілей та корпоративного громадянства. Для досягнення цих цілей підприємства беруть на себе певний ризик. Баланс між ризиком та винагородою – це постійна проблема, незалежно від того, які дії виконуються. Одним з сучасних інструментів управління ризиками в процесі антикризового управління є техніка «краватка-метелик» (Bowtie), яку можна використовувати для візуалізації, оцінки та безпосередньо управління ризиками. Аналіз «краватка-метелик» – це методологія якісної оцінки ризику, яка забезпечує спосіб ефективної візуалізації складних сценаріїв ризику у зручному для розуміння графічному форматі та показує взаємозв’язок між причинами небажаних подій та вірогідністю збільшення втрат та збитків. Bowtie може відображати дії, що запобігають появі та розвитку ризику на підприємстві, а також відновлювальні заходи, які дозволяють обмежити можливі ефекти після настання даного ризику, специфічні для кожного достовірного результату.
АНАЛІЗ ПОДАТКОВИХ НАДХОДЖЕНЬ В СИСТЕМІ ДОХОДІВ БЮДЖЕТУ УКРАЇНИ
Authors: Тітенко Зоя , Ворона Ангеліна
Published: January 2022

Актуальність теми дослідження обумовлена тим, що в сучасних умовах питання забезпечення наповнення дохідної частини бюджету з метою виконання покладених на державу функцій набуває все більшої актуальності. У результаті аналізу досліджено обсяг та структуру податкових надходжень до державного бюджету України за 2018-2020 роки. Визначено, що на даному етапі розвитку системи оподаткування в Україні слід удосконалювати ефективність податкового законодавства, підвищити податковий контроль, знизити загальний рівень оподаткування. У процесі дослідження використано наукові методи: економіко-статистичний – для оцінювання динаміки обсягу податкових надходжень в структурі доходів державного бюджету; аналізу і синтезу – для з’ясування причин, які спричиняють зміну обсягів доходів державного бюджету; абстрактно-логічний – при здійсненні теоретичних та методичних узагальнень. Обґрунтовано, що дослідження обсягів і структури податкових надходжень, є необхідним етапом при здійсненні ефективного управління фінансовими ресурсами держави.
Pengaruh Penggunaan Teknologi Informasi, Motivasi Kerja, dan Kepuasan Kerja Terhadap Kinerja Guru SMA Negeri 82 Jakarta Selama Masa Pandemi Covid-19
Authors: Pratiwi Mutiara Sari
Published: January 2022

Perubahan sistem pendidikan akibat pandemi covid-19 telah menghasilkan kebijakan baru dalam proses pembelajaran dengan bantuan teknologi canggih dan perangkat internet. Meskipun internet dan teknologi bukanlah hal baru dan asing bagi masyarakat Indonesia, namun tidak dapat dipungkiri bahwa kemampuan penggunaan alat-alat teknologi di Indonesia belum sepenuhnya terdistribusi, terutama bagi para lansia dan sekolah-sekolah di daerah tertentu. Oleh karena itu, pada kenyataannya di masa covid-19 ini masih ada proses pembelajaran dengan hanya memberikan tugas melalui aplikasi chat WhatsApp tanpa ada interaksi tatap muka melalui Gmeet atau Zoom. Hal yang sama dialami oleh guru di SMA Negeri 82 Jakarta dan mempengaruhi kualitas kinerja yang dihasilkan guru. Agar berbanding lurus antara kinerja guru dengan tujuan pendidikan yang ditetapkan pemerintah, maka guru sebagai sumber daya manusia utama dalam organisasi harus berkompeten dengan memenuhi berbagai kompetensi penilaian. Untuk meningkatkan kompetensi guru perlu memahami pemanfaatan teknologi, motivasi dan kepuasan kerja sebagai pendorong untuk melahirkan semangat kerja guru dalam melaksanakan pekerjaannya.
Evaluation opportunities of SEM pictures by CAD software
Authors: Ficzere Péter , Lukács Norbert László
Published: January 2022

Nowadays the different 3D printed components are often produced for direct use. In this case the components need to be mechanical designed, therefore the material properties must be well known. It is a fact that the printing parameters have a significant effect on the printing quality. The interference between the printing parameters and the mechanical solidity is well known however the reason for this phenomenon is not. For a deeper investigation a scanning electron microscope is needed. Our study is focused on the potential evaluation of results with the help of the CAD software.
Effect of the welding parameters on residual stresses in pipe weld using numerical simulation
Authors: Alhafadhi Mahmood , Krállics György
Published: January 2022

The objective of this article is to predict the residual welding stress in a dissimilar pipe weld. The 2D model, instead of 3D was used to reduce the time and cost of the numerical calculation. The 2D numerical simulation MSC MARC code is used to predict the residual stress developed during pipe welding. The present model was validated using hardness measurement. Good agreement was found between the measurement and numerical simulation results. The effects of welding parameters on residual stress field on the outer and inner surface were assessed. The effect of welding parameter (welding current) is examined. The axial and hoop residual stresses in dissimilar pipe joints of different thickness for pipe weld were simulated in outer and inner surfaces. When the other parameters remain fixed, and the current has great effect on the weld shape and size, and then affects the residual stress level significantly.
The possibilities of intelligent manufacturing methods
Authors: Ficzere Péter , Lukács Norbert László
Published: January 2022

Additive production technologies made the realization of individually designed, highly complicated geometric structures in practically all fields of industry and human therapy (implantation) possible. In order to minimalize the risk of failure originating from production technology the continuous development of measurements technologies provides the possibility to track the parameters of production and if necessary to ensure their modification. The great number of recorded production data (big data) at the same time can be used in the quality control of the product.
Control of a cable robot on PSOC cypress platform
Authors: Kapitány Pálma , Lénárt József
Published: January 2022

This paper deals with the control of a cable model robot. The continuous motion of the end effector is provided by velocity control of four DC motors. In each uniform time step the rotational speed of the motors are predicted based on the assumption of constant path velocity of the end effector in order to move it to prescribed position. In the next time step the rotational speed of the motors are calculated from the difference between the actual position and the target one. This way the discrepancy between the actual position and the prescribed one is corrected step-by-step. The control algorithm is implemented on Cypress Semiconductor CY8CKIT PSoC 5LP microcontroller.
Mismatch effect on fatigue crack propagation limit curves of GMAW joints made of S960QL and S960TM type base materials
Authors: Mobark Haidar , Lukács János
Published: January 2022

Welded structures cannot be produced without imperfections, cracks or crack like defects. Among the structural steels, 960 MPa strength category represents a reliable application possibility. Consumables are also available, but the behaviour of mismatch types under cyclic loading condition is not yet clear. In order to know the fatigue crack propagation resistance of 960 MPa strength category steels and their gas metal arc welded joints fatigue crack growth tests were performed. The tests results were analysed and fatigue crack propagation limit curves were determined.
Analysis of DMU40 machine centre by vibration measurement
Authors: Kiss Róbert , Szilágyi Attila
Published: January 2022

This article is part of a longer research-analytical work, because it outlines the results and conclusions of the study according to the main topic of the research and the applied method. The central theme of the research is the dynamic stiffness of machine tools and the various methods for their determination. Following analytical analysis the machine tool natural frequencies were determined using a finite element software (ANSYS Workbench R19.1), which we now approach from a practical point of view, that is determined in the workshop by measurements. The results obtained are compared for each of the three methods.
Dynamical Simulation of a CNC Turning Centre
Authors: Al-Zghoul Mohammad , Szilágyi Attila
Published: January 2022

This paper shows the most common rotor systems which can be used to analyse a CNC turning center. Starting with the simplest rotor system representation (single-degree-of-freedom) up to analysing multi-degree-of-freedom and infinite-degree-of-freedom rotor systems using the TMM (Transfer Matrix Method) when it comes to cases like multi desk rotors and Jeffcott-rotors.
Prototype for fit investigations
Authors: Alsardia Talal , Lovas László , Ficzere Péter
Published: January 2022

Nowadays, additive manufacturing is a powerful tool and promising technology both for manufacturing and educational purposes. This work aims to present a case study of using 3 dimensional (3D) printing technology for fit investigations. It describes the creation of a physical model (prototype) by using the Fused Deposition Modeling (FDM) method. The prototype of two plates was made to perform an inspection how the prototype fits with other components.
Evaluation of Pharmacology MCQ Papers of MBBS Professional Examinations
Authors: Paul Chowdhury Dipak Kumer , Saha Debashish , Habib Md Ahsan
Published: January 2022

This cross sectional descriptive study was conducted to observe the quality of Pharmacology professional MCQ papers of different Universities of Bangladesh. For this purpose, total 80 MCQ papers of five universities dated from January 2007 to July 2015 were reviewed against a checklist to find out the coverage of recall, understanding and problem solving type questions, content coverage and construction of each question. The mean of recall, understanding and problem based type questions of all the universities were 92.1, 7.8 and 0.1 respectively and all of them statistically significantly differed from curriculum standard. All of the MCQ papers contained more than 75% recall type questions and 27.5% MCQ papers had only recall questions, Only 1(1.2%) MCQ papers contained 100 % topics (all the 11 groups). Eighteen (22.5%) contained 10 groups and 26.3% contained 9 groups out of 11. Forty percent MCQ papers contained less than 80% topics. Most of the stems of the MCQ were in the form of incomplete sentence (53.5%), 28.4% were in the form of complete statement and 16.8% were in the form of single word. Only 0.4% stem were in the form of clinical scenario. Fifty (62.5%) MCQ papers had defective stems and 68.75% had defective options. Total 14 (17.5%) MCQ papers were without any flaw but the rest 88.5% MCQ papers were with flaws either defective stem or faulty options or both. Findings of this study may be used to redefine the distribution of different type of questions in SAQ papers and to improve the quality of question papers by ensuring their coverage.
Bangladesh Journal of Medical Education Vol.13(1) January 2022: 49-57
Integrated Teaching: the Need of the Hour
Authors: Dubhashi Siddharth P , Dubhashi Riddhima S , RajatSindwani -
Published: January 2022

Integration means a systemic organization of teaching matter pertaining to different disciplines coordinating delivery of the learner to give a holistic approach to medical study. The objective of this study is to compare the effectiveness of integrated with traditional teaching. Twenty integrated and ten traditional sessions were conducted over five semesters. Duration of each session was 90 minutes. Sample sizes for integrated and traditional groups were respectively 5600 and 1400 students. Pre and post- test scores for integrated, pre and post- test scores for traditional and post-test scores for integrated and traditional teaching groups were compared. Faculty and students’ feedback were analyzed. Difference in Pre and Post-Test scores for integrated teaching was statistically highly significant. Difference in Pre and Post-Test scores in traditional teaching group, though statistically significant, was less than that observed with integrated teaching .The difference in Post-Test scores obtained in integrated and traditional teaching groups was statistically highly significant. Ninety four percent Faculties agreed that integrated teaching was an effective mode of training. Ninety percent faculties rated the program on a higher scale. Ninety five percent students liked the concept of integrated teaching. .Student-centered, patient-oriented approach is the fruitful outcome of the integrated teaching model, which will definitely help us to have a much needed “Basic Doctor.”
Bangladesh Journal of Medical Education Vol.13(1) January 2022: 79-86
EU STRATEGIC INTERESTS IN KAZAKHSTAN IN THE CONTEXT OF GEOPOLITICAL AND GEO-ECONOMIC CHANGES IN THE REGION WITH FOCUS ON CHINA
Authors: DRIENIKOVÁ KRISTÍNA , ZUBAĽOVÁ ĽUBICA
Published: January 2022

Kazakhstan has an important position as the EU´s main trading partner in Central Asia and the EU has been its largest trade partner as well as the largest source of foreign direct investment. The importance of China as trade and investment partner is rising, on the contrary, the EU’s share is declining. Even though there remains plenty of scope for further growth, mutual relations and cooperation are influenced by increased geopolitical tensions and geo-economic changes in the wider region. The paper evaluates the position of the EU and its strategic interests in Kazakhstan in the context of geopolitical and geo-economic changes in the region based on the assessment of the trade and investment position of the EU in comparison with the position of China.
Análisis de la realización de espectáculos televisivos en directo: Italia en Eurovisión 2021
Authors:   Universidad de Granada, Gómez-Pérez Francisco Javier , Pérez-Rufí José Patricio ,   Universidad de Málaga
Published: January 2022

This paper aims to study the production of live television at the Eurovision Song Contest, a contest characterized by the use of avant-garde and experimental technologies and staging. The filming and production of the winning performance in 2021, «Zitti e buoni», by the Italian group Måneskin, is selected as a case study, as it breaks with previous trends. The main objectives of this research are to analyze the selected performance from a discursive and formal perspective and to identify the visual references on which the production is based. We apply a formal audiovisual analysis while considering intertextual practices and the intention to appropriate pop culture references. The formal audiovisual analysis highlights the respect for a functional and classic audiovisual grammar that tries to make itself invisible to highlight the members of the band with their charisma. Faced with previous practices trying to break spatial and temporal continuity, the performance claims a classical audiovisual grammar and an apparently simple staging based on nostalgia.
Estrategia programática en Instagram de los candidatos en las elecciones autonómicas de la Comunidad de Madrid 2021
Authors: Moreno Díaz Julio
Published: January 2022

La investigación analiza el uso de la red social Instagram como herramienta para la difusión de las líneas programáticas de partido en las elecciones a la Comunidad de Madrid en 2021. Para ello se presta atención a la gestión y visibilidad de las publicaciones de los candidatos, la composición temática de los programas electorales y su argumentación en la red social, así como a las posibles estrategias usadas en este medio como complemento a la celebrificación del líder. A través de una metodología basada en el análisis de contenido, complementado con un análisis cualitativo, se estudia una muestra compuesta por 377 posts publicados en los perfiles de los seis aspirantes a la presidencia autonómica. El estudio aborda variables como el formato de contenido, el escenario de actuación, el protagonismo del líder y la correspondiente argumentación propagandística. Los resultados muestran el potencial de Instagram en la divulgación de los planes de acción política, a pesar de la falta de una estrategia común que la fomente como un canal de comunicación real con el electorado. Además, se precisa la personalización del candidato, el componente ideológico de las publicaciones y la determinación de la actualidad electoral durante la campaña.
Possible Counterexample of the Riemann Hypothesis
Authors: Vega Frank
Published: January 2022

Under the assumption that the Riemann hypothesis is true, von Koch deduced the improved asymptotic formula $\theta(x) = x + O(\sqrt{x} \times \log^{2} x)$, where $\theta(x)$ is the Chebyshev function. A precise version of this was given by Schoenfeld: He found under the assumption that the Riemann hypothesis is true that $\theta(x) < x + \frac{1}{8 \times \pi} \times \sqrt{x} \times \log^{2} x$ for every $x \geq 599$. On the contrary, we prove if there exists some real number $x \geq 2$ such that $\theta(x) > x + \frac{1}{\log \log \log x} \times \sqrt{x} \times \log^{2} x$, then the Riemann hypothesis should be false. In this way, we show that under the assumption that the Riemann hypothesis is true, then $\theta(x) < x + \frac{1}{\log \log \log x} \times \sqrt{x} \times \log^{2} x$.
Saying NO To Biometrics
Authors: Teeluckdharry Guru Dev
Published: January 2022

This paper has been prepared to challenge the MNIS (Mauritius National Identity Scheme) in Mauritius. In the UK, the biometric national ID scheme was junked in 2010. Should Mauritius learn from the UK? A number of courts' decisions with respect to biometric data schemes have been analysed in depth. The dangers and risks of biometric technologies have been exposed. Even if the so called judgemental interferences of biometric technologies especially biometric IDs and databases with the human life (in the presence of adequate legal safeguards) could exceptionally be justified legally, there are ethical and social ramifications which illustrate that this is also an intrusion on human rights and should not be permissible at all.
BUSINESS NETWORKING, MARKETING AND INDUSTRY ANALYSIS: A Proposed Framework for SMEs in Mauritius
Authors: Teeluckdharry Guru Dev
Published: January 2022

This paper is about the proposal of a framework for SMEs in Mauritius. It brings solutions to the weakness concerning the development of the SME industry in Mauritius and also proposes a framework for it in the context of globalisation. Such an initiative would allow SMEs to expand into large enterprises (LEs) and would be considered as ‘Gateways to Larger Enterprises’.
Microbial Responses to the Reduction of Chemical Fertilizers in the Rhizosphere Soil of Flue-Cured Tobacco
Authors: Shen Min-Chong , Zhang Yu-Zhen , Bo Guo-Dong , Yang Bin , Wang Peng , Ding Zhi-Yong , Wang Zhao-Bao , Yang Jian-Ming , Zhang Peng , Yuan Xiao-Long
Published: January 2022

The overuse of chemical fertilizers has resulted in the degradation of the physicochemical properties and negative changes in the microbial profiles of agricultural soil. These changes have disequilibrated the balance in agricultural ecology, which has resulted in overloaded land with low fertility and planting obstacles. To protect the agricultural soil from the effects of unsustainable fertilization strategies, experiments of the reduction of nitrogen fertilization at 10, 20, and 30% were implemented. In this study, the bacterial responses to the reduction of nitrogen fertilizer were investigated. The bacterial communities of the fertilizer-reducing treatments (D10F, D20F, and D30F) were different from those of the control group (CK). The alpha diversity was significantly increased in D20F compared to that of the CK. The analysis of beta diversity revealed variation of the bacterial communities between fertilizer-reducing treatments and CK, when the clusters of D10F, D20F, and D30F were separated. Chemical fertilizers played dominant roles in changing the bacterial community of D20F. Meanwhile, pH, soil organic matter, and six enzymes (soil sucrase, catalase, polyphenol oxidase, urease, acid phosphatase, and nitrite reductase) were responsible for the variation of the bacterial communities in fertilizer-reducing treatments. Moreover, four of the top 20 genera (unidentified JG30-KF-AS9, JG30-KF-CM45, Streptomyces, and Elsterales) were considered as key bacteria, which contributed to the variation of bacterial communities between fertilizer-reducing treatments and CK. These findings provide a theoretical basis for a fertilizer-reducing strategy in sustainable agriculture, and potentially contribute to the utilization of agricultural resources through screening plant beneficial bacteria from native low-fertility soil.
Protein Tyrosine and Serine/Threonine Phosphorylation in Oral Bacterial Dysbiosis and Bacteria-Host Interaction
Authors: Ren Liang , Shen Daonan , Liu Chengcheng , Ding Yi
Published: January 2022

The human oral cavity harbors approximately 1,000 microbial species, and dysbiosis of the microflora and imbalanced microbiota-host interactions drive many oral diseases, such as dental caries and periodontal disease. Oral microbiota homeostasis is critical for systemic health. Over the last two decades, bacterial protein phosphorylation systems have been extensively studied, providing mounting evidence of the pivotal role of tyrosine and serine/threonine phosphorylation in oral bacterial dysbiosis and bacteria-host interactions. Ongoing investigations aim to discover novel kinases and phosphatases and to understand the mechanism by which these phosphorylation events regulate the pathogenicity of oral bacteria. Here, we summarize the structures of bacterial tyrosine and serine/threonine kinases and phosphatases and discuss the roles of tyrosine and serine/threonine phosphorylation systems in Porphyromonas gingivalis and Streptococcus mutans, emphasizing their involvement in bacterial metabolism and virulence, community development, and bacteria-host interactions.
The Precautionary Principles of the Potential Risks of Compound Events in Danish Municipalities
Authors: Modrakowski Luise-Ch. , Su Jian , Nielsen Anne B.
Published: January 2022

The risk of compound events describes potential weather and climate events in which the combination of multiple drivers and hazards consolidate, resulting in extreme socio-economic impacts. Compound events affecting exposed societies can therefore be deemed a crucial security risk. Designing appropriate preparation proves difficult, as compound events are rarely documented. This paper explores the understanding and practices of climate risk management related to compound events in specific Danish municipalities vulnerable to flood hazards (i.e., Odense, Hvidovre, and Vejle). These practices illuminate that different understandings of compound events steer risk attitudes and consequently decisions regarding the use of different policy instruments. Through expert interviews supported by policy documents, we found that the municipalities understand compound events as either a condition or situation and develop precautionary strategies to some extent. Depending on their respective geographical surroundings, they observe compound events either as no clear trend (Odense), a trend to be critically watched (Hvidovre), or already as a partial reality (Vejle). They perceive flood drivers and their combinations as major physical risks to which they adopt different tailor-made solutions. By choosing a bottom-up approach focusing on local governance structures, it demonstrated that the mismatch between responsibility and capacity and the ongoing separation of services related to climatic risks in the Danish municipality context need to be critically considered. The findings highlight that the complex challenge of compound events cannot be solved by one (scientific) discipline alone. Thus, the study advocates a broader inclusion of scientific practices and increased emphasis on local focus within compound event research to foster creative thinking, better preparation, and subsequently more effective management of their risks.