bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of the potential biological value of pyruvate dehydrogenase E1 subunit β in human cancer
Authors: Rong Yao , Liu Song-Hua , Tang Ming-Zheng , Wu Zhi-Hang , Ma Guo-Rong , Li Xiao-Feng , Cai Hui
Published: January 2024

BACKGROUND

The pyruvate dehydrogenase E1 subunit β (PDHB) gene which regulates energy metabolism is located in mitochondria. However, few studies have elucidated the role and mechanism of PDHB in different cancers.

AIM

To comprehensive pan-cancer analysis of PDHB was performed based on bioinformatics approaches to explore its tumor diagnostic and prognostic value and tumor immune relevance in cancer. In vitro experiments were performed to examine the biological regulation of PDHB in liver cancer.

METHODS

Pan-cancer data related to PDHB were obtained from the Cancer Genome Atlas (TCGA) database. Analysis of the gene expression profiles of PDHB was based on TCGA and Genotype Tissue Expression Dataset databases. Cox regression analysis and Kaplan-Meier methods were used to assess the correlation between PDHB expression and survival prognosis in cancer patients. The correlation between PDHB and receiver operating characteristic diagnostic curve, clinicopathological staging, somatic mutation, tumor mutation burden (TMB), microsatellite instability (MSI), DNA methylation, and drug susceptibility in pan-cancer was also analyzed. Various algorithms were used to analyze the correlation between PDHB and immune cell infiltration and tumor chemotaxis environment, as well as the co-expression analysis of PDHB and immune checkpoint (ICP) genes. The expression and functional phenotype of PDHB in single tumor cells were studied by single-cell sequencing, and the functional enrichment analysis of PDHB-related genes was performed. The study also validated the level of mRNA or protein expression of PDHB in several cancers. Finally, in vitro experiments verified the regulatory effect of PDHB on the proliferation, migration, and invasion of liver cancer.

RESULTS

PDHB was significantly and differently expressed in most cancers. PDHB was significantly associated with prognosis in patients with a wide range of cancers, including kidney renal clear cell carcinoma, kidney renal papillary cell carcinoma, breast invasive carcinoma, and brain lower grade glioma. In some cancers, PDHB expression was clearly associated with gene mutations, clinicopathological stages, and expression of TMB, MSI, and ICP genes. The expression of PDHB was closely related to the infiltration of multiple immune cells in the immune microenvironment and the regulation of tumor chemotaxis environment. In addition, single-cell sequencing results showed that PDHB correlated with different biological phenotypes of multiple cancer single cells. This study further demonstrated that down-regulation of PDHB expression inhibited the proliferation, migration, and invasion functions of hepatoma cells.

CONCLUSION

As a member of pan-cancer, PDHB may be a novel cancer marker with potential value in diagnosing cancer, predicting prognosis, and in targeted therapy.
Early gastric cancer recurrence after endoscopic submucosal dissection: Not to be ignored!
Authors: Zeng Yan , Yang Jian , Zhang Jun-Wen
Published: January 2024

This editorial comments on the article “Efficacy of multi-slice spiral computed tomography in evaluating gastric cancer recurrence after endoscopic submucosal dissection”. We focus on the importance of paying more attention to post-endoscopic submucosal dissection (ESD) gastric cancer recurrence in patients with early gastric cancer (EGC) and how to manage it effectively. ESD has been a well-known treatment and the mainstay for EGC, with the advantages of less invasion and fewer complications when compared with traditional surgical procedures. Despite a lower local recurrence rate after ESD, the problem of postoperative recurrence in patients with EGC has become increasingly non-ignorable with the global popularization of ESD technology and the increasing number of post-ESD patients.
Responsibility for Violation of Rights of Migrants in Libyan Detention Centre
Authors: Mohammad Bitar  , Benarji Chakka
Published: January 2024

Migrants in Libya are experiencing the worst form of human rights violations, particularly after the fall of the Gaddafi regime. Post-2014 migrants faced a serious threat of human rights violations in detention centres and became the most vulnerable in Libyan society. The migrants experienced various human rights violations such as murder, torture, rape, enforced disappearance, and forced labour that may amount to crimes against humanity in international criminal law. In light of this situation, European policies aim at returning migrants to the European coasts. This has led to the conclusion of bilateral and multilateral migration agreements with the Libyan government and armed non-state actors. These policies have contributed to the vulnerability of migrants and the legitimization of violations by armed non-state actors. This article examines the violations committed against migrants in detention centres in Libya under the national and international legal framework with the aim of revealing the shortcomings and gaps in the Libyan national legal system and identifying the responsibility of the Libyan government, European Union countries and non-state actors for violations committed against immigrants in Libya.
the Merangkaikan Diri Di Padang Pastoral Digital: Kaum Muda Berkatakese Di Tengah Tantangan Hidup Menggereja
Authors: Pranoto Damianus Suryo , Son Oktovianus
Published: January 2024

Teknologi digital telah membawa dampak yang signifikan terhadap cara kaum muda berinteraksi dan mengembangkan identitas mereka. Dalam konteks ini, pastoral digital kaum muda seringkali dihadapkan dengan tantangan-tantangan yang dapat memengaruhi identitas dan perilaku, bisa berdampak negatif maupun positif. Teknologi digital dapat menjadi suatu sarana untuk membantu seseorang dalam berkreatif atau berkembang terutama dalam berpastoral atau mewartakan iman. Metode yang digunakan adalah kualitatif dengan melakukan wawancara untuk menyelidiki pandangan kaum muda Katolik terhadap penggunaan teknologi digital dalam konteks keagamaan. Hasil yang didapat adalah ketika kaum muda merangkaikan diri di dunia digital, hal ini menjadi sebuah manifestasi nyata dari bagaimana spiritualitas dapat bersinergi dengan teknologi, membentuk wadah inklusif di mana iman dan kehidupan sehari-hari saling melengkapi.
Karakteristik Produksi Bandikut (Echymipera kalubu) di Kampung Nuni Distrik Pantura Kabupaten Manokwari Provinsi Papua Barat
Authors: Pawere Frandz Rumbiak , Dwi Nurhayati
Published: January 2024

Abstract 
The characteristics of bandicoot (E. kalubu) production can be used as a standard for assessing bandikut productivity. Where body measurements can provide an overview of the exterior of the bandicoot which can be used to predict the live and carcass weight of the bandicoot. The purpose of this study was to develop bandicoot as hopeful animals in meeting the animal protein needs of the Papuan people. The method used in this research is descriptive method with case study technique. The case is the E.kalubu in Nuni Village. The sampling technique was random as many as 30 individuals for production characteristics. The results of this study were that there were 4 variables that could be used as estimators of body weight and carcass of male bandicoot kalubu, namely heart girt, hind leg length, body length, and canone bone with a coefficient of determination for body weight of 0.937 and carcass weight of 0.931. The best predictor variable for body weight and carcass was body length.
Keywords: Bandicoot; Characteristic; Kalubu; Production
 
Abstrak
Karakteristik produksi bandikut bisa dijadikan standar untuk menilai produktivitas bandikut. Dimana ukuran-ukuran tubuh dapat memberikan gambaran eksterior bandikut yang bisa digunakan untuk memprediksi bobot hidup dan bobot karkas bandikut. Tujuan penelitian ini adalah untuk pengembangan bandikut sebagai hewan harapan dalam pemenuhan kebutuhan protein hewani masyarakat Papua. Metode yang digunakan pada penelitian ini adalah metode deskriptif dengan teknik studi kasus. Yang menjadi kasus adalah bandikut (E.kalubu) yang ada di Kampung Nuni. Teknik pengambilan sampel secara acak sebanyak 30 ekor untuk karakteristik produksi. Hasil penelitian ini adalah terdapat 4 variabel yang dapat digunakan sebagai penduga bobot badan dan karkas bandikut kalubu jantan yaitu lingkar dada, panjang kaki belakang, panjang badan, dan canone bone dengan koefisien determinasi untuk bobot badan sebesar 0,937 dan bobot karkas sebesar 0,931. Variabel penduga bobot badan dan karkas terbaik adalah panjang badan.
Kata kunci: Bandikut; Karakteristik; Kalubu; Produksi
Deteksi Dermatofitosis pada Kucing Domestik di Surabaya dengan Menggunakan Woodlamp
Authors: Wardhani Hana , Rahmaniar Reina , Widhowati Dyah
Published: January 2024

Abstract 
In Surabaya, a study focused on detecting dermatophytosis in domestic cats using a Woodlamp. The research observed cat samples with hair and skin issues, concentrating on lesions and changes in skin and fur. While Woodlamp is more effective for Microsporum canis, it lacks a green fluorescence reaction for Trychopyton. About 50% of ringworm cases fluoresced under the Woodlamp, turning infected cats' fur green. Skin lesion samples were taken for superficial mycosis identification, and ectoparasite presence was examined through hair combing. Out of 50 examined cats, 8 had ectoparasites 4 with fleas (Ctenocephalides felis) and 4 with tick infestations (Felicola subrostrate). Woodlamp results showed qualitative detection of fungi in 14% of cases. The prevalence of ectoparasite infestation was 16%, with Ctenocephalides felis being dominant. No mites were found. Only 14% of cases revealed dermatophytosis through Woodlamp examination, indicating the presence of ectoparasite infestations in 16% of Surabaya's domestic cats.
Keywords: Cat; Dermatofitosis; Woodlamp
 
Abstrak 
Kucing merupakan hewan yang memiliki daya tarik tersendiri karena tubuh yang mudah dipeluk, warna mata yang indah dan warna rambut yang beragam. Penelitian ini bertujuan untuk mengetahui dermatofitosis pada kucing domestik dengan menggunakan Woodlamp di Surabaya. Sampel kucing dengan ciri-ciri mengarah pada permasalahan rambut bahkan kulit. Metode pengamatan pada bentuk lesi dan adanya perubahan pada kulit serta rambut. Pemeriksaan biasanya penggunaan Woodlamp lebih efektif untuk jamur Microsporum canis, tetapi untuk jamur Trychopyton tidak ada reaksi berpendar hijau. Pengujian menggunakan alat Woodlamp sekitar 50% dari ringworm akan muncul. Bulu dari kucing yang terinfeksi jamur akan menyala hijau saat terkena Woodlamp. Identifikasi mycosis superficial lesi kulit harus diambil sampelnya dari tepi lesi. Kemudian pemeriksaan dilanjutkan karena adanya ektoparasit (Pinjal, Kutu dan Caplak) dengan cara melakukan penyisiran rambut. Dari data yang diperoleh pada 50 ekor kucing yang diperiksa di sekitar Surabaya, terdapat 8 ekor kucing yang positif terinfeksi ektoparasit sebesar 4 ekor (pinjal (Ctenocephalides felis), dan 4 ekor kucing terinfestasi kutu (Felicola subrata). Hasil dari pemeriksaan jamur menggunakan woodlamp menunjukkan sejumlah 7 kucing (14 %)  secara kualitatif terdeteksi adanya jamur, dengan adanya warna hijau berpendar pada kulit yang dilakukan pemeriksaan menggunakan Woodlamp. Prevalensi dari infestasi ektoparasit pada kucing yaitu 16%. Sedangkan kucing lainnya tidak terinfeksi oleh parasit (84%). Sehingga terdapat infestasi ektoparasit pada kucing domestik di Kota Surabaya. Jenis ektoparasit yang ditemukan yaitu pinjal Ctenocephalides felis sebagai ektoparasit dominan, berikutnya yaitu kutu Felicola subrostrate. Hasil pemeriksaan tidak ditemukan tungau. Dermatofitosis dengan pemeriksaan Woodlamp hanya 14 %.
Kata kunci: Dermatofitosis; Kucing; Woodlamp
Changes in cytokine complexes in children with autoimmune diseases with different effectiveness of their biological therapy
Authors: Radygina Tatiana V. , Fisenko Andrey P. , Petrichuk Svetlana V. , Kuptsova Darya G. , Kurbatova Olga V. , Freydlin Ekaterina V. , Potapov Alexander S. , Murashkin Nikolay N. , Bursagova Bella I. , Abdullaeva Luizat M. , Semikina Elena L.
Published: January 2024

Introduction. Cytokines (CC) play an important pathogenetic role in the development of autoimmune diseases. Over the past decade, there has appeared a huge number of biological drugs that target certain cytokines. The main problem remains the choice of a suitable biological drug, as up to 40% of patients do not respond to treatment or become resistant to it. Aim: to identify informative cytokine complexes in children with psoriasis, MS, and IBD with different efficacy of biological therapy. Materials and methods. Two hundred eighty eight children with autoimmune diseases were examined against the background of supportive biological therapy. Patients were divided into groups of exacerbation and remission depending on the lesion area index PASI for psoriasis (PS), clinical activity indices PUCAI for ulcerative colitis (UC), PCDIA for Crohn’s disease (CD), by the pre­sence of foci of demyelination on MRI for patients with multiple sclerosis (MS). All patients underwent a study of 25 cytokines in serum samples using multiplex analysis (X-MAP technology). Results. In PS, MS, UC, and CD patients, an increase in pathogenetically significant cytokine profiles associated with cells (c) and functions (f) of M1 cells, Th1, Th2, Th17 was revealed in the exacerbation of diseases relative to the groups in remission. There was a significant decrease in the levels of cytokines and cytokine complexes in patients with MS relative to patients with PS, UC and CD, with the exception of cTh1. Threshold values of the level of cytokine complexes above which the development of an exacerbation of the disease can be expected were obtained: for PS — 1431.1 pg/ml (fTh22 — IL13 + Il22), for PC — 33.1 pg/ml (cTh1 — IFN-γ + IL12p70 + TNF-β + IL2), UC — 20.9 pg/ml (M1 — IL-1 + IL-6 + TNF-α), CD — 1986 pg/ml (fIL12 — IL12 + IL23 + IL27). Conclusion. To assess the effectiveness of biological therapy and to predict the condition of patients, it is possible to evaluate specific cytokine complexes for a specific pathology.
Diagnostic delay in inflammatory bowel diseases in children
Authors: Prokhorenkova Marina O. , Nosenko Kristina M. , Orlova Mariya A. , Vinokurova Anna V. , Kazakova Vlada A. , Koroleva Olga A. , Dorogov Anton Yu. , Potapov Alexandr S.
Published: January 2024

Introduction. The incidence and prevalence of inflammatory bowel disease (IBD) in children is increasing steadily. The diagnosis is often delayed that can lead to an increased risk of complications and significantly decrease the quality of life in the child. The identification of reasons associated with prolonged diagnostics must bring down healthcare costs, reduce the frequency of surgical interventions and use of biological agents. The aim of our study was to determine the duration of diagnosis and associated factors in IBD children.
Materials and methods. The research held at the National Medical Research Center for Children’s Health included the analysis of three hundred sixty four medical records of children diagnosed with ulcerative colitis (UC) or Crohn’s Disease (CD). This investigation assessed the time of onset of the first symptoms, the first visit to a doctor, the time of establishing the diagnosis, and the first symptoms. The diagnostic time and delay for all IBD were determined.
Results. The study included 286 patients, including 157 CD and 129 UC. The diagnostic delay was 18 months for CD, and 6 months for UC. The manifestation of the disease with extraintestinal symptoms in CD was found to increase the chance of a diagnosis duration of more than 18 months by 8.88 times (95% CI 3.4–23.06, p < 0.001), and in UC — more than 6 months by 4.98 times (95% CI 1.52–16.3, p = 0.009). Moreover, the absence of liquid stools, blood in the stool, low-grade fever, and abdominal pain in CD can lead to an increase in diagnostic time. It was also found that UC boys are diagnosed much longer.
Conclusion. CD requires more time to make a diagnosis than UC, which is due to the peculiarity of the clinical course of the di­sease. Despite the fact that a doctor has consulted patients in time, a delay in establishing a diagnosis occurred at the examination stage, so that requires additional alertness from the specialist’s side.
Characteristics of Streptococcus pneumoniae strains serotype 19A isolated from children in Moscow during the post-vaccination period (2015–2022)
Authors: Alyabyeva Nataliya M. , Komyagina Tatiana M. , Tryapochkina Anastasiya S. , Lazareva Anna V.
Published: January 2024

Introduction. Community-acquired pneumonia (CAP) is a leading cause of children mortality and morbidity worldwide. The introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) had a very good effect on the CAP prevalence. However, serotype 19A remains the leading cause of severe pneumococcal disease in both vaccinated and unvaccinated children.
The purpose of the work. To analyze the clonal epidemiology and sensitivity to antibacterial drugs of pneumococcus serotype 19A strains in the post-vaccination period for monitoring and control of vaccination.
Materials and methods. The study included twenty six isolates of pneumococci serotype 19A isolated in children in Moscow between 2015 and 2022. Serotyping was carried out using the Neufeld capsule swelling test. Sensitivity was determined using the microdilution method. Resistance genes and multilocus sequence typing was performed using the PCR method.
Results. By 2019–2022 the detection rate of serotype 19A decreased from 61.5% to 38.5%. A total of 12 different sequence types were identified. Most isolates belonged to 2 clonal complexes: CC230 (n = 15), CC320 (n = 6). Sixteen isolates exhibited a multidrug resistance phenotype (MDR). The dominant phenotype was extremely drug-resistant in the combination of β/Eri/Cli/TMP/Tet (43.8%). The most of MDR isolates belonged to clonal complexes: CC230 (8/16), CC320 (6/16) and Singleton 16988 (12.5%).
Conclusion. After the introduction of PCV13, the prevalence of serotype 19A decreased, but MDR isolates of this serotype continued to increase. These results highlight the need for continued monitoring of the pneumococcal population exhibiting high resistance to reduce the risk of severe disease caused by this organism.
Associations of vitamin D receptor gene polymorphism with idiopathic hypercalciuria in children
Authors: Strozenko Ludmila A. , Micheeva Nataliya M. , Lobanov Yuriy F. , Zverev Yakov F. , Tekuteva Nadezhda A.
Published: January 2024

Introduction. Idiopathic hypercalciuria (IH) is one of the most common metabolic disorders in children and can lead to the development of urolithiasis over childhood. In this regard, studying the etiology of this pathological condition will help to prevent the development of IH and reduce the risk of developing urolithiasis.
Study purpose: to study the role of genetic polymorphisms of the VDR gene in the development of IH in children and their relatives of the first and second lines of kinship.
Materials and methods. The study included 68 people, including 35 children aged of 3 to 17 years with identified hypercalciurine and 33 first- and second-line relatives with IH and urolithiasis. A study of the level of 25-OH vitamin D in blood plasma and a genetic study for the presence of polymorphisms of the vitamin D receptor gene VDR were carried out including: BsmI Polymorphism IVS10+283G>A, A-3731G (Cdx2), FokI Polymorphism; Ex4+4T>C. To compare the frequency of occurrence of vitamin D receptor (VDR) genotypes, samples of conditionally healthy individuals permanently residing in Kemerovo and natives of the European part of the Russian Federation were taken. At the same time, for the VDR G283A (BsmI) gene, a healthy sample consisted of 232 people from Kemerovo and 96 cases from the European part of Russia, for the VDR A-3731G gene — 269 and 243 people, and for the VDR FokI TC gene — 172 and 96 people, respectively.
Results. Reducing the content of 25(OH)D in the blood of less than 30 ng/ml was detected in 33 (48.5%) IH children. 25 (OH)D level below 20 ng/ml was detected in 15 (22.1%) patients. In IH patients and level 25(OH)D in the blood of less than 20 ng/ml, the homozygous variant 283 GG of the VDR gene (BsmI) was found in 20% of the examined versus 51% (p = 0.028) of conditionally healthy individuals. The heterozygous genotype of 283 PA of the VDR gene (BsmI) was determined in 73.3% of IH patients versus 41.7% of conditionally healthy individuals (p = 0.027). The heterozygous Ex4+4TC genotype of the VDR Fokl gene was recorded in 66.7% of the examined IH patients and low serum vitamin D levels (< 20 ng/ml) when compared with the level in conditionally healthy individuals (p = 0.030). In patients with low vitamin D levels against IH background, the proportion of the minor allele A 283 of the VDR gene (BsmI) was determined significantly more often than in healthy individuals (p = 0.044).
Conclusion. A relationship was identified between polymorphism of the vitamin D receptor gene VDR (polymorphic marker BsmI (rs1544410) of the VDR gene 283G>A; polymorphic marker Fokl (rs2228570) of the VDR gene Ex4+4T>C) with IH and deficiency of 25(OH)D levels in the blood serum of children.
Modern risk scales in pediatrics and pediatric cardiac surgery as tools for assessing the quality of medical care
Authors: Sarsenbaeva Gulzhan I.
Published: January 2024

Introduction. The review presents the characteristics of modern risk scales in pediatrics. A comparative analysis of the advantages and disadvantages of risk scales in pediatric cardiac surgery has been carried out. Early detection of high-risk patients was shown to be the basis for the prevention of adverse outcomes after cardiac surgery. The capabilities of the Aristotle School (Aristotle Basic Complexity (ABC) Score have been established as a tool for assessing the quality of surgical treatment of children with congenital heart defects (CHD). Its determinants are mortality, the complexity of the postoperative period, and the technical complexity of the operation. The correlation between the values of the ABC scale and its determinants was evaluated. If the values of all three determinants exceeded the upper limit of the 95% confidence interval (CI), the patient was included in the high-risk group. The quality of treatment was assessed by the performance index (IP). A close correlation between ABC and its determinants has been revealed. For the ABC school, a high accuracy of the prognosis of death, complications, and technical complexity was established with an optimal threshold value of 6.5 points. Patients with ABC above the threshold were more likely to die. The IP was 0.56, similar indicators of foreign clinics ranged from 0.46 to 0.62 points.
Conclusion. The basic Aristotle scale and new risk stratification scales after cardiac surgery in children are effective systems for evaluating the results of surgical treatment of CHD patients of different levels of complexity can be used to determine the quality of surgical treatment and identify high-risk groups.
Role of lipids in nutrition of premature babies with bronchopulmonary dysplasia
Authors: Basargina Milana A. , Skvortsova Vera A. , Kharitonova Nataliya A. , Illarionova Mariya S. , Pinaeva-Slysh Evgeniya L.
Published: January 2024

Introduction. The review is devoted to the importance of lipids in the nutrition of premature infants with bronchopulmonary dysplasia (BPD). In recent years, the proportion of children born prematurely especially babies with very low and extremely low body weight, has been increasing due to the introduction of reproductive technologies that allow women with various pathologies and health abnormalities having children, as well as the use of modern neonatal intensive care and intensive care facilities. One of the most common diseases in such patients is BPD. An important component of the system of caring for prematurely born infants is adequate nutrition, which plays an important role in the development and maturation of all organs and systems, including lung tissue, changing its morphology. It is important to note that in severe BPD, there is a direct relationship between nutritional status, normal lung function, and psychomotor development of the infant. Therefore, the nutritional needs of premature BPD infants are increased and this imposes special requirements on their admission and individual dietary correction, taking into account all the features of the child’s development and the presence of concomitant pathology. The optimal nutrition for a premature baby is recognized as mother’s milk, which is enriched with breast milk. However, the fat component (the main energy substrate) is either absent in the fortifier, or lipids amounts in to fail to be sufficient. The use of specialized mixtures also does not overlap the caloric content of the diet to provide the growth rate of BPD infant against the background of increased energy needs by 15–25% when compared with patients without BPD) and the necessary restriction of the volume of injected fluid due to the high risk of hypervolemia of the small circulatory circle.
Conclusion. Thus, an additional supply of medium-chain triglycerides seems to be a promising direction that increases the fat component of the diet and, as a result, its energy value in conditions of limiting fluid intake in premature BPD infants.
IDENTIFICATION OF FACTORS INFLUENCING HEART FAILURE MORTALITY USING MACHINE LEARNING METHODS
Authors:   Siberian Federal University, KUKARTSEV V.V. , ZAMOLOTSKY S.A. ,   Siberian Federal University, KHRAMKOV V.V. ,   SibGU named after M.F. Reshetnev
Published: January 2024

Mining is an important industry that plays a crucial role in the extraction of natural resources. However, this work can often be hazardous and pose significant risks to worker health and safety. It is very important for companies to prioritize worker safety and implement the most effective preventative measures to mitigate the effects. To improve working conditions and reduce risks, a study was conducted to identify the factors most influencing fatalities and create a model for prediction. A dataset, of eleven binary, integer and rational attributes and a binary output variable was processed and visualized. An experiment was conducted investigating the predictions using a decision tree, which showed higher accuracy after feature selection. As a result, the most significant influencing factors were identified; also proposed two classifiers that can be used for mortality prediction, which will improve the working conditions in the workplace and increase the efficiency of the mining industry.
ENVIRONMENTAL PROBLEMS OF TECHNOGENOUSLYDEFORMED SOILS OF THE ABSHERON PENINSULA
Authors:   Institute of Geography named after acad. G.A. Aliyeva, HAJIYEVA G.N.
Published: January 2024

In addition to rich deposits of oil, gas and gas condensate, the Apsheron Peninsula has widespread mineral deposits (limestone, gypsum, crushed stone, bentonite, sand, etc.). Currently, the accumulation of waste in the territory of quarries and dumps after the extraction of non-metallic minerals on a large scale has led to the formation of technogenically disturbed areas. On the territory of the quarries themselves and adjacent lands, well-developed soils are widespread (irrigated ordinary gray soils with different granulometric composition and thickness, semi-desert gray-brown soils). During the extraction of deposits, as a result of the use of multiton machines and mechanisms, these lands were subjected to varying degrees of technogenic degradation, lost their fertility and have not yet been studied either genetically or economically. Therefore, when writing this article, the main goal was a large-scale study of these lands and the development of recommendations for their restoration.
USING RECYCLED CRUSHED CONCRETE COLUMNS TO STABILIZE FULLY SATURATED SILTY CLAY SOIL
Authors:   Don State Technical University, AL-EQABI H.H.A. , PROKOPOV A.YU. ,   Don State Technical University
Published: January 2024

The improvement of fully saturated silty clay soil using columns of recycled crushed concrete is the subject of this paper's laboratory model studies. This study is being done to examine how recycled crushed concrete affects settlement control and bearing capacity. The research also examined the variation in subgrade modulus as well as the cause of a shallow circular footing's failure on soil where silt clay layer soil had been substituted with recycled broken concrete. The results demonstrated that combining both a partly replaced column of silty clay soil and a column of recycled crushed concrete significantly improves load bearing capability. The approach used may drastically alter the footing's stress displacement curve when it is resting on silty clay soil, reduce settlement, and make the replacement soil block within the container act as a deep foundation. Consequently, a foundation supported by silty clay may have its bearing capacity failure mechanism changed at the top of a column constructed of recycled crushed concrete, from exclusive settling to general bearing capacity failure. The use of fills with shattered concrete in them, whether natural or manmade, is growing. Hence, research into the bearing and deformation properties of this material is important for application areas such road construction, soil replenishment, and embankments.
PROSPECTS FOR THE INTEGRATION OF METHODS OF OIL EXTRACTION AND UNDERGROUND LEACHING OF METALS
Authors:   Moscow Polytechnic University, GOLIK V.I. ,   Vladikavkaz Scientific Centre of the Russian Academy of Sciences, BURDZIEVA O.G. ,   Vladikavkaz Scientific Centre of the Russian Academy of Sciences
Published: January 2024

The prospects of improving the technologies of oil extraction from solid hydrocarbon raw materials are considered. The idea of combining technologies by combining mine and borehole development with technologies of chemical exposure to raw materials is detailed. A new technology of integration of methods of borehole mining and underground leaching of metals is considered. Underground-surface mining provides an increase in the income-news index and profitability of oil production from solid hydrocarbons, including from man-made resources.
INTEGRATION OF ENRICHMENT MODULES INTO TECHNOLOGICAL SYSTEMS OF COAL DEPOSITS MINING
Authors:   Institute for Problems of Integrated Development of Subsoil named after Academician N.V. Melnikov of the Russian Academy of Sciences, DMITRAK YU.V. , ATRUSHKEVICH V.A. , KRAVTSOV A.A. ,   Institute for Problems of Integrated Development of Subsoil named after Academician N.V. Melnikov of the Russian Academy of Sciences
Published: January 2024

The results of studies devoted to the development of a variety of options, including combined, development of reservoir deposits by developing and implementing modules for primary processing and enrichment into the technological production system are presented. Innovative technical devices are presented that make it possible to design flexible adaptive mining systems for a wide range of mining and geological conditions, ensuring efficiency, improving the quality of coal products and mining safety.
POWER MANAGEMENT FOR A COPPER PRODUCTION PLANT
Authors:   Moscow Polytechnic University, KLYUEV R.V. , BOSIKOV I.I. ,   North Caucasian Institute of mining and metallurgy (State Technological University), GAVRINA O.A. ,   North Caucasian Institute of mining and metallurgy (State Technological University), ZAOUI CH.E. ,   Moscow Polytechnic University
Published: January 2024

The paper considers the issues of managing the power consumption of an enterprise for the production of copper. The solution of these issues was carried out during the instrumental examination of the power supply system (SES) of the enterprise based on the results of a comprehensive energy audit. An analysis was made of the dynamics of electricity consumption for 2015-2018. It has been established that the uniformity of electricity consumption for production is maintained. The average monthly electricity consumption for 2017 was: for technology - 39,637 thousand kWh; for general shop expenses (general plant) - 6942 thou- sand kWh; in general, for production - 46579 thousand kWh. The total electricity consumption for production by product type is presented, taking into account the auxiliary consumption of all sections for the period 2015-2017. It was found that, compared with 2015, electricity consumption in 2017 for the most energy-intensive processes for electrolytic and blister copper and decreased by 6 % and 1.5 %, respectively, at the same time, an increase in consumption was observed for the production of technical sulfur, in 2016 by 7 %, in 2017 by 15 %...
IMPROVING THE METHODOLOGY FOR OPTIMIZING THE PLACEMENT OF INCISORS ON THE EXECUTIVE BODIES OF A ROADHEADERS
Authors:   Tula State University, ZHABIN A.B. , LINNIK YU.N. ,   State University of Management, POLYAKOV A.V. ,   LLC "Unified Consulting Holding», LINNIK V.YU. ,   State University of Management
Published: January 2024

The technique of optimizing the placement of incisors on the executive body of a roadheaders is considered. A detailed description of the calculation algorithm is given. The limits of variation of the main parameters and quality criteria are determined. A mathematical description of the condition of the intersection of the tool holders is presented, which is an important stage of optimization.
DEVELOPMENT OF INNOVATIVE TECHNOLOGY OF UNDERGROUND METHOD OF FASTENING THE WORKINGS WITH ROCK MELT
Authors:   Ural State Mining University, VALIEV N.G.O. , DICK YU.A. ,   Research and Design Institute "Uralmekhanobr", PETROV V.P. ,   Research and Design Institute "Uralmekhanobr", BUDNIK D.R. ,   Research and Design Institute "Uralmekhanobr"
Published: January 2024

The research is carried out in order to find an alternative method of fixing the mine workings, corresponding to the mining-geological and mining-technical conditions of finding the mine workings and ensuring safety of mining operations. Based on the analysis of mining-geological and technical conditions of mines, the experience of using stone casting in related industries and a possible alternative option are considered. For further study of the proposed hypothesis of the stone-casting method of fixing mine workings, variants of directions for studying the properties of rocks are proposed. The research is aimed at fixing the mine workings with a molten rock, which is formed under the influence of an electric arc, including the formation of a monolithic reinforced layer due to the modified rock created along the perimeter of the workings.
PERSPECTIVE FOR IMPROVING THE METHODS OF FIXING MINE WORKINGS IN SALT ROCKS OF DIFFERENT STRENGTH
Authors:   Institute for Problems of Integrated Development of Subsoil named after. acad. N.V. Melnikov Russian Academy of Sciences, RYLNIKOVA M.V. , SAKHAROV E.M. ,   «EuroChem VolgaKaliy» LLC, ESINA E.N. ,   Peoples' Friendship University of Russia named after Patrice Lumumba
Published: January 2024

Ensuring the operability of the support of mine workings supported in various conditions of subsurface development is one of the most important and difficult to solve problems in the mining industry. The reason for the low stability of underground workings is the insufficient bearing capacity of anchors, especially with a long service life. A decrease in the bearing capacity of the anchor support over time occurs as a result of natural processes of deformation of rocks, a decrease in strength and corrosion of the support elements in aggressive environments. With the weakening of the bearing capacity of the anchors, the displacements of the rock contour of the workings increase, the number and width of cracks in the roof rocks increases, local rock falls and local blockages of mine workings appear. It is shown that the choice of the type, structure and parameters of the anchor support that ensures the stability of deep-lying underground mine workings in a complex-structured, multi-strength, multi-modular array of layered enclosing rocks with complex morphology and the presence of flexural disturbances of the silvinite formation of a potash deposit should be made differentially taking into account the geological structure of the array behind the contour of the workings, which determines the specifics of loading components along the length of the anchor.
SELECTION OF THE TYPE AND SUBSTANTIA TION OF THE DESIGN OF A STRONG ANCHOR FOR MINE WORKINGS IN THE DEVELOPMENT OF DEEP DEPOSITS OF POTASSIUM SALT
Authors:   Institute for Problems of Integrated Development of Subsoil named after Melnikova, RYLNIKOVA M.V. , SAKHAROV E.M. ,   «EuroChem-VolgaKaliy» LLC, NEUGOMONOV S.S. ,   Institute for Problems of Integrated Development of Subsoil named after Melnikova
Published: January 2024

The article presents the peculiarities of the Gremyachinskoe potash salt deposit development conditions, which influence the choice of type and justification of anchoring design. The practice of anchoring of mine workings in salt rocks at great depths is generalized. The factors influencing the choice of the type and parameters of anchoring of mine workings are systematized. The parameters of anchor support are substantiated on the basis of establishing the regularities of deformation of the system "anchor-rock massif" in time to ensure the operational reliability of the support and stability of mine workings with the definition of parameters of rational use of improved designs of anchor support.
MODELING THE IMPACTS OF WATER EROSION OF ANTHROPOGENIC MINERAL FORMATIONS ON THE ENVIRONMENT
Authors:   Tula State University, KACHURIN N.M. , PROKHOROV D.O. ,   Tula State University, LUSKIN G.G. ,   LLC "Roscontract", AMBARTSUMOV D.A. ,   "NPP "Ruskhimsintez"LLC
Published: January 2024

The processes of runofffrom anthropogenic mineral formations of rain and melt water and their impact on the environment are considered. A mathematical apparatus for modeling the formation of wastewater costs is given. The process of runoff infiltration from anthropogenic mineral formations in the adjacent territories is also considered. Equations are obtained for modeling runoff infiltration in adjacent areas. The results of computational experiments are presented.
STUDIES ON ESTIMATING MODERN GEODYNAMIC ACTIVITY WITH ELECTRIC MEDIUM GRADIENT METHOD
Authors:   Institute of Mining Ural Branch of the Russian Academy of Sciences, DALATKAZIN T.SH. , VEDERNIKOV A.S. , GRIGORIEV D.V. ,   Institute of Mining Ural Branch of the Russian Academy of Sciences
Published: January 2024

The article presents the results of studying the possibility of joint application of one of the techniques of electrical exploration and geodetic monitoring for geodynamic assessment of the stress-strain state of the massif from the surface. Modern geodynamic activity indirectly affects the change in the values of apparent electrical resistivity of the array, as the movement of rocks leads to changes in the volume of pores and cracks, which are often filled with aqueous solutions. In addition, the distribution of electrical properties of rocks in the near-surface part of the section is influenced by meteorological conditions. At the same time, the influence of meteorological conditions on the section is distributed uniformly, and in order to exclude the influence of their change between observation series, it is proposed to use normalization of measured values of apparent resistivity of rocks. The results obtained are a prerequisite for the continuation of research on the use of the median gradient methodology in the complex of geodynamic diagnostics.
HORIZONTAL ROTATION OF DEFORMED ELEMENTS OF THE EARTH'S SURFACE
Authors:   Federal State Budgetary Institution ", ANTONOV V.A. ,   Institute of Mining Engineering, Ural Branch of the Russian Academy of Sciences"
Published: January 2024

The structural composition and properties of the horizontal rotation of the elements of the Earth's surface, which is part of the skew-symmetric part of the geomechanical distortion tensor, are investigated. It is established that it consists of a real rotation, showing the rotation of a deformed area element in geospatial space, and a virtual one, displaying its artificial rotation. The decomposition of angular deformations into components leading to real and virtual rotation, as well as the calculation of their angles, is carried out according to the presented nomogram and the formulas attached to it. Practical examples show the deformation and rotation of complex contours of man-made mining facilities located on differently moving blocks of the Earth's surface.
THE ETHERNET ECOSYSTEM AS A BASIS FOR THE ENERGY ECONOMY OF BIG DATA
Authors:   Institute of Oil and Gas Problems of the Russian Academy of Sciences, EREMIN N.A. , EREMINA P.N. ,   Gubkin Russian State University of Oil and Gas (National Research University)
Published: January 2024

The future development of the Russian energy sector will be based on the energy economy of big high-frequency data. Russia has begun preparing a new national project to build a big data economy during the year. High-frequency big geodata is a new stage in the development of the digital energy economy. The digital modernization of the Russian energy industry is a key driver of the resource-innovative development of the Russian Big Data economy.
INFLUENCE OF THE CLIMATE FACTOR ON THE DEVELOPMENT OF MOUNTAIN GEOSYSTEMS AND EMERGING ENVIRONMENTAL PROBLEMS
Authors:   Nakhchivan State University, IBRAGIMOVA L.P.
Published: January 2024

Being one of the main components of the ecosystem, the climate plays an important role in the development of various economic areas of the territory, including the resettlement of the population. Climatic factors, such as temperature, precipitation, wind, etc., have a special impact on the development of agriculture - agrocenoses, as well as tourism. The article studies the influence of climatic features of the Nakhichevan Autonomous Republic on the development of agricultural areas of the territory. At the same time, special attention was paid to temperatures above 50 and 100C, the humidity coefficient, the continuity of sunny days, and the total amount of radiation. It should be noted that each of the climatic factors was analyzed separately, the degree of suitability and development of the study area for the development of agrocenoses was studied, and the environmental problems that arose and may arise during this period were studied.
Evaluation of Open Circuit Voltages (OCV) of Microbial Fuel Cells from Cow and Pig Dungs
Authors: Lawal Muyideen O. , Olaniyan Oluwaseyi P. , Elijah Bamidele A. , Adetoro Mariam , Adelakun Pelumi A. , Adeniran Abdulrasaq O. , Akinde Sunday B.
Published: January 2024

A microbial fuel cell (MFC) has many potential applications, including wastewater treatment, environmental monitoring and bioenergy production. The comparison of the open circuit voltages OCV values for three MFC set-ups using cow dung, pig dung and the combination of cow and pig dungs was carried out in this study.  The MFC fabricated locally consist of two chambers – the anode, which is an anaerobic digestion of organic waste with an electrode on top of the digester lid while potassium permanganate was mixed with water in a chamber to form the cathode with an electrode on top of the lid. The two chambers were linked with a proton exchange membrane (PEM) made with agarose agar using PVC pipe.  For 30 days, the OCV of the MFC set-ups were recorded. The OCV values for the three set-ups were compared. According to the results, the average OCV values for cow dung, pig dung, and a mixture of both are 1.014 V, 0.610 V and 0.430 V, respectively. This shows that cow dung produced the highest OCV values, followed by pig dung. The OCV values from the mixture of both had the lowest results.
Reservoir Structural and Stratigraphical Evaluation of Sapele Deep Field, Niger Delta, Southern Nigeria.
Authors: Airen John O. , Mujakperuo Bernard J.
Published: January 2024

Throughout the course of a field's existence, the oil and gas industry has not been very good at determining and forecasting how the stratigraphical and structural makeup of reservoirs will affect fluid flow. With harder-to-find reserves and growing development costs, it is critical to have a comprehensive plan in place to identify and reduce risks and uncertainties related to the stratigraphical and structural framework of reservoirs. Improving predictive capability is therefore the main task of our day. The research area's outlined strata thickens from north to south. On the other hand, the research area's considerable fault density is revealed by the structural interpretation. There is a noticeable throw to these faults, which may provide a route for the migration and deposit of hydrocarbons. Anticlines, which are important components of the majority of the Niger Delta's massive oil fields and have the potential to have several pay horizons, are typical structural types. The two defined horizons in the research region contain Sweet Spots (Bright spots), according to the Root-Mean Square Amplitude map analysis. 3D seismic cube and well log data were used to assess the research area's reservoir structural and stratigraphical framework. The study region is located between 50 33' 42.22" E and 50 53' 54.43" N.
Analysis and Development of Military Helmet Using Date Palm Fibre Reinforced Epoxy Composite
Authors: Jibrin Nura , Isyaku Bashir K. , Gidado Auwal Y. , Abubakar Saidu B.
Published: January 2024

The study discusses on analysis, fabrication and characterization of military helmet using date palm fibre reinforced with epoxy. The study is aimed at identifying the possibility of using the locally available material such as date palm fibre for the production of military protective helmet. Composite plates were prepared using Date palm fibre (DFE) reinforced with epoxy with varying composition. Six samples were produced and cut into the required size and shape for testing mechanical properties (impact strength ASTM D-156, Hardness ASTM D-2240, tensile strength ASTM D-638 and flexural strength ASTM D-790) of the material. Based on the result obtained, sample label S3   has 20% DFE and 80% epoxy has the highest impact strength of 0.225 J/mm2, hardness 70 Hv, tensile strength 25.87 N/mm2 and flexural strength. The scan electron microscopy (SEM) was carried on the selected sample in which voids were observed in the image which could be instrumental to air trapped in the composite during mixing which might have escaped during curing at high temperature living the void in the sample. The helmet was produced using the selected sample with a thickness of 8mm while that of Daungkumsawat, et al (2020) has a thickness of 6.94mm