bluuebunny/crossref_metadata_2025 huggingface dataset:
Extraction, Purification, and Development of Sublingual Film (SLIT
Films) Comprising Cockroach Allergen for Treatment of Allergy
Authors: Anita Leishangthem , D. P Venkatesh , B Sajeev Kumar , Kanni Paranjothy , Ramnarayanan Chandramouli , Karki Roopa , Komarla Nagendra Prasad , Janadri Suresh
Published: June 2022

Aim:

Allergy associated with cockroaches are mostly from the American cockroach (Periplaneta americana) and German cockroach (Blattella germanica). The effective and safe treatment for cockroach allergy is Sublingual immunotherapy (SLIT). In this study SLIT Films containing purified allergen extract of Periplaneta americana were prepared by solvent casting and were evaluated for their efficiency in delivery.

Methodology:

Cockroach allergen extract was prepared and purified by ultrafiltration and chromatography. The molecular weight of protein content was identified and estimated by SDS- PAGE and ELISA. SLIT films were developed by the Quality by Design (QbD) approach and were evaluated for allergen-excipient compatibility, swelling index, taste, diffusion, in vitro dissolution, local toxicity, and stability analysis.

Results:

Cockroach allergen protein extracts (cut-off 25-71KDa) were identified by SDS-PAGE and quantified by indirect ELISA, further selected for sublingual film preparation. The indirect ELISA results show a higher optical density (OD) value compared to crude extract. The weight uniformity and thickness of the film were between 13-18 mg and 0.04-0.06 mm. The disintegration time was found to be less than 1 min. The cumulative percentage release was also found to be satisfactory.

Conclusion:

SLIT Film containing cockroach allergen from Periplaneta americana were successfully developed and evaluated. SLIT films of cockroach allergen could be more beneficial and convenient for emergency use in patients when compared to subcutaneous immunotherapy. SLIT films provide dose accuracy and are a promising alternative for SCIT and SLIT drops and tablets.
Acute and Subchronic Treatment of Roasted and Unroasted Argan Oil on Postprandial Glycemia and Its Effect on Glucose Uptake by Isolated Rat Hemidiaphragm
Authors: Daoudi Nour Elhouda , Bouhrim Mohamed , Bouziane Omar , Abdnim Rhizlan , Bouknana Saliha , Elrherabi Amal , Mekhfi Hassane , Aziz Mohammed , Legssyer Abdelkhaleq , Ziyyat Abderrahim , Bnouham Mohamed
Published: June 2022

Background:

Argan oil is one of the products used for antidiabetic purposes in Morocco.

Objective:

This work aims to study the acute and subchronic effect treatment of the roasted (Roil) and unroasted (UnRoil) Argan oils on oral glucose tolerance test (OGTT) and body weight in normal and diabetic rats, evaluate the effect of these oils on glucose absorption by the diaphragm and determine total polyphenol, flavonoids, tannins, chlorophyll and carotenoids amounts.

Methods:

The anti-hyperglycemic effect of Roil and UnRoil was investigated in normal and alloxanediabetic rats by treating the animals orally with 2 mLKg-1/day of oils for 1 day (Acute treatment) and 4 weeks (Subchronic treatment). Then, OGTT was carried out at the end of each treatment, and the body weight was checked for each week. Besides, these oils (1 gL-1) were tested on glucose absorption by the diaphragm isolated from Wistar rats in vitro.

Results:

This work shows that Roil and UnRoil significantly decrease the postprandial glycemic level in acute and subchronic treatments in normal and diabetic rats. Besides, the intake of these oils in diabetic rats significantly attenuates the postprandial glycemia compared to the acute-treated group. In vitro glucose uptake by the hemidiaphragm study shows that Argan oils promote glucose consumption by the muscles.

Conclusion:

Argan oils showed a very important anti-hyperglycemic effect, which could be explained by promoting peripheral glucose uptake. UnRoil shows a better effect than Roil on glucose consumption, meaning that the roasting process influences the phytoconstituent responsible for this activity.
Preclinical Large Animal In-Vivo Experiments for Surgically Implanted
Atrioventricular Valve: Reappraisal and Systematic Review
Authors: Sazzad Faizus , Kollengode Ramanathan , Beverly Chan Li Xuan , Kiat Tan Ying , Ganesh Geetha , Kofidis Theo
Published: June 2022

Background:

The development of atrioventricular bioprosthesis has witnessed an
increasing drive toward clinical translation over the last few decades. A significant challenge in the
clinical translation of an atrioventricular bioprosthesis from bench to bedside is the appropriate
choice of a large animal model to test the safety and effectiveness of the device.

Methods:

We conducted a systematic review of pre-clinical in vivo studies that would enable us to
synthesize a recommended framework. PRISMA (Preferred Reporting Items for Systematic Reviews
and MetaAnalyses) guidelines were followed to identify and extract relevant articles.

Results:

Sheep was the most common choice of animal, with nine out of the 12 included studies
being conducted on sheep. There were acute and chronic studies based on our search criteria. An
average of ~20 and 5 animals were used for chronic and acute studies. One out of three acute
studies and eight out of nine chronic studies were on stented heart valve bioprosthesis. All analyses
were conducted on the implantation of atrioventricular valves with trileaflet, except for one chronic
study on unileaflet valves and one chronic and acute study on bileaflet valves.

Conclusion:

Understanding the variance in past pre-clinical study designs may increase the appropriate
utilization of large animal models. This synthesized evidence provides a pre-clinical in vivo
studies framework for future research on an atrioventricular bioprosthesis.
A Study of Variance and its Utility in Machine Learning
Authors: Sharma Krishna Gopal , Singh Yashpal
Published: June 2022

With the availability of inexpensive devices like storage and data sensors, collecting and
storing data is now simpler than ever. Biotechnology, pharmacy, business, online marketing websites,
Twitter, Facebook, and blogs are some of the sources of the data. Understanding the data is crucial today
as every business activity from private to public, from hospitals to mega mart benefits from this.
However, due to the explosive volume of data, it is becoming almost impossible to decipher the data
manually. We are creating 2.5 quintillion bytes per day in 2022. One quintillion byte is one billion Gigabytes.
Approximately, 90% of the total data is created in the last two years. Naturally, an automatic
technique to analyze the data is a necessity today. Therefore, data mining is performed with the help of
machine learning tools to analyze and understand the data. Data Mining and Machine Learning are
heavily dependent on statistical tools and techniques. Therefore, we sometimes use the term – “Statistical
Learning” for Machine Learning. Many machine learning techniques exist in the literature and
improvement is a continuous process as no model is perfect. This paper examines the influence of variance,
a statistical concept, on various machine learning approaches and tries to understand how this
concept can be used to improve performance.
Worship with Children. Agentive Participation in Dutch Protestant Contexts
Authors: Van Leersum-Bekebrede Lydia
Published: June 2022

Summary of the dissertation "Worship with Children. Agentive Participation in Dutch Protestant Contexts".
Penerapan Model Pendidikan Karakter Pengajaran Vokasi (Modikar Pekasi) Kelompok Mata Kuliah Teori Kejuruan di FT UNY
Authors: Kusuma Rosanti , Jaedun Amat
Published: June 2022

ABSTRACTThe purpose of this study was to determine: (1) the understanding of FT UNY lecturers on MODIKAR PEKASI; (2) practical application of MODIKAR PEKASI in teaching vocational theory courses at FT UNY; and (3) the effectiveness of the theoretical application of MODIKAR PEKASI in integrating character values in group teaching of vocational theory courses at the FT UNY. The data were collected using descriptive quantitative methods with the type of survey research through questionnaire, with a lecturer who teaches vocational theory courses at the FT UNY as respondents. Quantitative data analysis used descriptive statistics, while qualitative data used thematic analysis. The results showed: (1) the lecturers' understanding of MODIKAR PEKASI was in the "very understanding" category with a value of X̅ = 3.35; (2) the practicality of MODIKAR PEKASI including the "easy to implement" model with a value of X̅ = 3.16; (3) the effectiveness of the PEKASI MODIKAR includes the "effective" model with the value of X̅ = 3.00. Thus, MODIKAR PEKASI in integrating character values through the teaching of vocational theory courses at FT UNY, theoretically can be understood and used practically and effectively.Keywords: model, character education, basic vocational, and vocationalABSTRAKTujuan penelitian ini adalah untuk mengetahui: (1) pemahaman dosen FT UNY terhadap MODIKAR PEKASI; (2) kepraktisan penerapan MODIKAR PEKASI dalam pengajaran mata kuliah teori kejuruan di FT UNY; dan (3) keefektifan penerapan MODIKAR PEKASI secara teoritis dalam mengintegrasikan nilai-nilai karakter pada pengajaran kelompok mata kuliah teori kejuruan di FT UNY. Data dikumpulkan menggunakan angket, dengan dosen pengampu mata kuliah teori kejuruan di FT UNY sebagai responden. Analisis data kuantitatif dengan statistika deskriptif, sedangkan data kualitatif dengan analisis tematik. Hasil penelitian menunjukkan: (1) pemahaman dosen terhadap MODIKAR PEKASI termasuk kategori “sangat paham” dengan nilai X̅ = 3,35; (2) kepraktisan MODIKAR PEKASI termasuk model yang “mudah dilaksanakan” dengan nilai X̅ = 3,16; (3) keefektifan MODIKAR PEKASI termasuk model yang “efektif” nilai X̅ = 3,00. Dengan demikian, MODIKAR PEKASI dalam mengintegrasikan nilai-nilai karakter melalui pengajaran mata kuliah teori kejuruan di FT UNY, secara teoritis dapat dipahami dan digunakan secara praktis dan efektif.
Strategi Jurusan Pendidikan Teknik Sipil dan Perencanaan Menghadapi Revolusi Industri 4.0: Studi Kasus di DIY
Authors: Hastutiningsih Arum Dwi , Sugiyono Sugiyono , Suyanto Suyanto , Wibowo Udik Budi
Published: June 2022

ABSTRACTIndustrial revolution 4.0 has brought about changes in various sectors, one of which is the management pattern applied in the Department of Civil Engineering and Planning Education. This study aims to find out how the Department of Civil Engineering and Planning deals with the impact of the industrial revolution 4.0, as well as analyze the strategies used to optimize productivity to prepare resources that can compete and have digital capabilities according to the standards of the industrial revolution 4.0 through the POAC (Planning, organizing process, Actuating, Controlling). This research uses descriptive qualitative research with an interview and documentation study. The results of the study show that the strategies that have been applied in dealing with the Industrial Revolution 4.0 in the world of education include strategies that are applied to HR management and management of existing infrastructure in the Department of Civil Engineering and Planning Education. The strategies applied to HR Management include further study schemes, individual competency development schemes, and industrial cooperation schemes, while the strategies applied to Facilities and Infrastructure Management include infrastructure development and media that can be used offline and online.Keywords: Civil Engineering, Human Resources Management, Industry Revolution 4.0, Infrastructure Management,ABSTRAKRevolusi industry 4.0 membawa dampak perubahan pada berbagai sector, salah satunya pada pola manajemen yang diterapkan di jurusan Pendidikan Teknik Sipil dan Perencanaan. Penelitian ini bertujuan untuk mengetahui bagaimana Jurusan Pendidikan Teknik Sipil dan Perencanaan menghadapi dampak Revolusi industry 4.0, serta menganalisis strategi yang digunakan untuk mengoptimalkan produktifitas dalam rangka menyiapkan sumber daya yang mampu bersaing serta memiliki kemampuan digital sesuai standar revolusi industry 4.0 melalui proses POAC (Planning, Organizing, Actuating, Controlling). Penelitian ini menggunakan metode penelitian kualitatif deskriptif dengan metode wawancara serta studi dokumentasi. Hasil penelitian menunjukkan strategi yang telah diterapkan dalam menghadapi Revolusi Industri 4.0 dalam dunia Pendidikan meliputi strategi yang diterapkan ke dalam manajemen SDM dan manajemen sarana prasarana yang ada dalam jurusan Pendidikan Teknik Sipil dan Perencanaan. Strategi yang diterapkan ke dalam Manajemen SDM meliputi skema studi lanjut, skema pengembangan kompetensi individu, dan skema kerjasama industri, sedangkan strategi yang diterapkan ke dalam Manajemen Sarana dan Prasarana meliputi pengembangan infrastruktur serta media yang dapat digunakan secara offline maupun online.
Implementing Technology Literacy Programs in Retirement Homes and Residential Care Facilities: Conceptual Framework
Authors: Li Karen S , Nagallo Nathan , McDonald Erica , Whaley Colin , Grindrod Kelly , Boluk Karla
Published: June 2022

Background

The COVID-19 pandemic caused widespread societal disruption, with governmental stay-at-home orders resulting in people connecting more via technology rather than in person. This shift had major impacts on older adult residents staying in retirement homes and residential care facilities, where they may lack the technology literacy needed to stay connected. The enTECH Computer Club from the University of Waterloo in Ontario, Canada created a knowledge translation toolkit to support organizations interested in starting technology literacy programs (TLPs) by providing guidance and practical tips.

Objective

This paper aimed to present a framework for implementing TLPs in retirement homes and residential care facilities through expanding on the knowledge translation toolkit and the framework for person-centered care.

Methods

Major concepts relating to the creation of a TLP in retirement homes and residential care facilities were extracted from the enTECH knowledge translation toolkit. The domains from the framework for person-centered care were modified to fit a TLP context. The concepts identified from the toolkit were sorted into the three framework categories: “structure,” “process,” and “outcome.” Information from the knowledge translation toolkit were extracted into the three categories and synthesized to form foundational principles and potential actions.

Results

All 13 domains from the framework for person-centered care were redefined to shift the focus on TLP implementation, with 7 domains under “structure,” 4 domains under “process,” and 2 domains under “outcome.” Domains in the “structure” category focus on developing an organizational infrastructure to deliver a successful TLP; 10 foundational principles and 25 potential actions were identified for this category. Domains in the “process” category focus on outlining procedures taken by stakeholders involved to ensure a smooth transition from conceptualization into action; 12 foundational principles and 9 potential actions were identified for this category. Domains in the “outcome” category focus on evaluating the TLP to consider making any improvements to better serve the needs of older adults and staff; 6 foundational principles and 6 potential actions were identified for this category.

Conclusions

Several domains and their foundational principles and potential actions from the TLP framework were found to be consistent with existing literatures that encourage taking active steps to increase technology literacy in older adults. Although there may be some limitations to the components of the framework with the current state of the pandemic, starting TLPs in the community can yield positive outcomes that will be beneficial to both older adult participants and the organization in the long term.
Antimicrobial Use in Pediatric Oncology and Hematology: Protocol for a Multicenter Point-Prevalence Study With Qualitative Expert Panel Assessment
Authors: Papan Cihan , Reifenrath Katharina , Last Katharina , Attarbaschi Andishe , Graf Norbert , Groll Andreas H , Huebner Johannes , Laws Hans-Jürgen , Lehrnbecher Thomas , Liese Johannes , Martin Luise , Tenenbaum Tobias , Weichert Stefan , Vieth Simon , von Both Ulrich , Hufnagel Markus , Simon Arne
Published: June 2022

Background

Because infections are a major driver of morbidity and mortality in children with hematologic or oncologic diseases, antimicrobials are frequently prescribed in pediatric oncology practice. However, excess or inappropriate use of antimicrobials is directly linked to the emergence of antimicrobial resistance. Although point-prevalence studies have examined the extent of antimicrobial use, a comprehensive qualitative evaluation of individual antimicrobial prescriptions remains lacking.

Objective

The aim of this study is to identify appropriate versus inappropriate antimicrobial use among pediatric cancer patients in a point-prevalence study, followed by an expert panel adjudication process and a subsequent report of these findings to participating centers. This study also aims to improve the quality of patient care by informing centers about discrepancies between internal standards of care and national guidelines.

Methods

Our point-prevalence study is performed at pediatric cancer centers in Germany and Austria. All patients under 18 years old who are hospitalized at the time of the study are included. As a supplement to the point-prevalence study, an expert panel is qualitatively assessing each of the antimicrobial prescriptions at the participating centers to review local guidelines and compare them with national guidelines.

Results

As of December 2021, the point-prevalence survey has been conducted at 30 sites and expert panel adjudication for qualitative assessment of each antimicrobial use is ongoing. Results of the study are expected in 2022.

Conclusions

This is the first point-prevalence study conducted among pediatric cancer centers with an integrated, multistep, qualitative approach that assesses each antimicrobial prescription. The results of this study will inform possible interventions for internal guidelines and antimicrobial stewardship programs implemented at pediatric cancer centers. In addition, local guidelines will be compared with national guidelines. Furthermore, this study will contribute to the overall integration of antimicrobial stewardship principles and initiatives in pediatric oncology and hematology, thereby improving safety and quality of care for children and adolescents with cancer and blood disorders.

International Registered Report Identifier (IRRID)

DERR1-10.2196/35774
A study of heart rate variability in diabetic mellitus patients
Authors: Jayachandra Srinivasa , Kodidala Satyanath Reddy
Published: June 2022

Background. Heart rate variability (HRV) is reduced in diabetes mellitus (DM) patients, suggesting dysfunction of cardiac autonomic regulation and an increased risk for cardiac events. Cardiac autonomic neuropathy (CAN), which results from damage to autonomic nerve fibers that innervate the heart and blood vessels, is a serious complication of DM. During progression of CAN, the parasympathetic nerve fibers innervating the heart are affected before the sympathetic nerve fibers leading to a reduced heart rate variability. The purpose of this study was to examine type 2 diabetes patients with heart rate variability in order to diagnose autonomic dysfunction and to relate the findings to other complications of diabetes mellitus. Materials and methods. 41 type 2 M patients and 45 age- and sex-matched controls were included. In the time domain we measured the mean R–R interval (NN), the standard deviation of the R–R interval index (SDNN), the standard deviation of the 5-min R–R interval mean (SDANN), the root mean square of successive R–R interval differences (RMSSD) and the percentage of beats with a consecutive R–R interval difference>50 ms (pNN50). In the frequency domain we measured high-frequency power (HF), low-frequency power (LF) and the LF/HF ratio. Results. There was no statistically significant difference between DM patients and controls for age and sex distribution. All time- and frequency-domain parameters except mean R–R interval and the LF/HF ratio were significantly lower in diabetes patients than in controls. When chronic complications of DM were examined, diabetic retinopathy and nephropathy were usually present together. For example, among six patients with nephropathy five also had retinopathy. There were 13 diabetes patients with complications (diabetic nephropathy and/or retinopathy) and nine patients with no diabetic complications. Although the chronological ages of the diabetes patients with and without complications were similar (53±9 and 49±12 years, respectively; P>0.05), the duration of DM in patients with complications was significantly greater than that of those without complications (14±9 versus 5±7 years; P=0.002). Diabetes patients had lower HRV values for time-domain and frequency-domain parameters than controls. Conclusions. Majority of heart rate variability parameters were lower in diabetes patients with chronic complications than in those without complications.
Pathogenesis of diabetic macular edema: the role of pro-inflammatory and vascular factors. Aliterature review
Authors: Kyryliuk M.L. , Suk S.A.
Published: June 2022

The review presents data on the pathogenesis of diabetic macular edema (DME). DME is a major cause of visual impairment in type 2 diabetes mellitus (DM) patients. Non-specific inflammation is an important factor of the underlying processes of DME. The importance of vascular endothelial growth factor (VEGF), interleukin-6, tumor necrosis factor-α (TNF-α), monocyte chemoattractant protein-1, vascular cell adhesion molecule-1 in the development of diabetes microvascular complications is indicated. Intercellular adhesion molecules (ICAM), particularly, soluble ICAM-1 (sICAM-1), are a local inflammatory mediator involved in the pathogenesis of diabetic injury to the layers of the eye. The literature is scant on the assessment of sICAM-1 in type2 DM patients with diabetic injury to the neurovascular system of the eye (i.e. adhesion of leukocytes to the vascular endothelium (leukostasis) and the concurrent endothelial apoptosis). There are three main stages of microvascular changes due to nonspecific inflammation: dilation of capillaries and increased blood flow, microvascular structural changes and leakage of plasma proteins from the bloodstream, transmigration of leukocytes through the endothelium and accumulation at the site of injury. Vascular dysfunction in diabetic retinopathy (DR) and DMЕ is caused primarily by leukostasis, which is based on the recruitment and adhesion of leukocytes to the retinal vascular system. Leukostasis is the first step in the sequence of adhesion and activation events that lead to the infiltration of leukocytes through the endothelium. Leukocytes involved in leukostasis induce vascular permeability by releasing cytokines, including VEGF and TNF-α, contributing to endothelial protein binding, increasing levels of reactive oxidative substances, and killing pericytes and astrocytes surrounding the endothelium. Thus, the existing data on the main aspects of the pathogenesis of DMЕ indicate that inflammation is an important factor in the processes underlying the development of DMЕ and DR. But a new understanding of the physiology of the retina suggests that the pathogenesis of retinal lesions in type 2 DM can be considered as a change in the neurovascular unit of the retina.
Factors that Influence Tourism Recovery, Post Disaster Earthquake in Sembalun Sub-District, East Lombok Regency
Authors: Fatini Muhammad Arif , Herwangi Yori
Published: June 2022

The impact of the earthquake in Lombok Island not only had an impact on community settlements, but also on tourism activities. Especially in Sembalun District, East Lombok, the impact can kill the economy of the community, since tourism is one of the main livelihoods of the people. The process of tourism recovery in Sembalun District shows different progress. Therefore, the purpose of this research is to compare the tourism performance before and after an earthquake—which was analyzed using comparative descriptive method. Furthermore, the next goal is to describe the recovery process of tourism in the aftermath of an earthquake, and identify factors that influence the achievement of tourism recovery using descriptive analysis. Based on the results of each purpose, it shows that there are several differences in the tourism performance before and after the earthquake; either it has better performance after the earthquake or worse. The process of tourism recovery is carried out differently— depending on the damage level. Nonetheless, there are several tourism objects that have not been recovered, such as Bale Adat. There are 4 factors that affect tourism recovery after an earthquake; physical factors, economic factors, social factors, and unique cultural factors.
Characteristics of the Former Salt Factory of Kalianget, Sumenep
Authors: Savila Vicelia Intan Savila , Rahmi Dwita Hadi
Published: June 2022

The term of morphology is widely used to describe the physical form of urban areas based on the historical city. The Old City of Kalianget is a modern city that was built as the salt briquette factory area during the colonial period in 1899. This study aims to identify the characteristics of urban morphology in the old city of Kalianget. The deductive qualitative method is used from the beginning of identifying the area problems, field survey and data analysis. This study uses the urban design theory by Roger Trancik. The urban design theory identifies morphology through figure ground analysis, linkage theory, and place theory. The study shows the land was dominated by the factory area in 1947 and has been dominated by the residence and abandoned buildings nowdays. Moreover, the road structure is formed with a grid pattern with the intersections between roads and dominated by T-junction. The center of the old city of Kalianget is an open space in the middle of the area characterized by the plots building. It closes to the open spaces and the main road has the larger size than the next layer.
Confianza en la gobernanza de aguas transfronterizas México-Estados Unidos: El caso de Tijuana-San Diego
Authors: Cáñez Cota Antonio
Published: June 2022

La gobernanza del agua es la capacidad directiva de las organizaciones que interpretan las prioridades de política pública, mientras que la gestión del agua es la mejor manera de implementar dichas prioridades. El propósito es explicar los habilitadores y obstáculos de la confianza entre actores binacionales que participan en la gobernanza de aguas transfronterizas entre Tijuana (México) y San Diego (Estados Unidos). La estrategia metodológica se basa en la revisión de actas binacionales, así como entrevistas semi-estructuradas a 31 actores de ambos lados de la frontera. El principal hallazgo es que la confianza se desarrolla a partir de una ética compartida, la cual se muestra en la cooperación entre pares; mientras que la confianza se restringe por los diferentes estilos de socialización de los actores. Se recomienda fomentar la confianza mediante la profesionalización de funcionarios de agua que atienden temas binacionales, para evitar la alta rotación de personal y la pérdida de aprendizajes.
Principios fundamentales para el diagnóstico, manejo y tratamiento de las infecciones odontogénicas. Revisión de la literatura
Authors: Esparza Loredo Susana Beatriz , Aranda Romo Ma. Saray , Noyola Frías Miguel Ángel , Sánchez Vargas Luis Octavio
Published: June 2022

Las infecciones odontogénicas (IO) son la principal causa de atención en la consulta dental, representan un número importante de ingresos hospitalarios en urgencias y unidades de cuidados intensivos, por lo que es pertinente la revisión de la literatura para sustentar la mayor evidencia científica, analizar y proponer acciones o principios para definir, diagnosticar y resolver efectivamente las infecciones odontogénicas, otorgando atención precisa que devuelva las funciones al sistema estomatólogico y que evite el uso inapropiado o indiscriminado de antibióticos. Está revisión se realizó entre el año 2006 y el 2018, incluye artículos de revisión, documentos de consenso y distintas guías clínicas, con base en ello, se proponen condiciones que identifican oportunamente la presencia de infecciones odontogénicas, factores asociados (clínicos y/o sistémicos) que pueden influir en el juicio del profesional para su manejo y las pautas de control y tratamiento de las infecciones odontogénicas.
Sífilis, la gran simuladora. Reporte de un caso
Authors: Leonardi Nicolás , Panico René Luis , Caciva Ricardo
Published: June 2022

Objetivo: Presentar un caso clínico de sífilis secundaria de localización bucal. Caso clínico: Hombre de 62 años, residente de la ciudad de Córdoba, Argentina, derivado al Servicio de Estomatología de la Facultad de Odontología, Universidad Nacional de Córdoba, con lesiones orales de tres semanas de evolución y supuesto diagnóstico de estomatitis aftosa. Clínicamente se observaron múltiples lesiones en la cavidad bucal localizadas en mucosa labial inferior, zona retrocomisural, cara ventral de lengua, tercio posterior de paladar blando y amígdalas, placas blancas de aspecto opalino compatibles con pápulas sifilíticas, dolorosas con adenopatías submaxilares y occipitales bilaterales positivas e indoloras. El diagnóstico presuntivo fue de sífilis secundaria. Se solicitaron estudios serológicos confirmando la presunción diagnóstica. El paciente fue derivado al Servicio de Infectología del Hospital Rawson donde recibió el tratamiento correspondiente. Conclusiones: Las lesiones bucales de las enfermedades venéreas son muy frecuentes. Sin embargo, son subdiagnosticadas debido a la inexperiencia de los profesionales sobre conceptos básicos de medicina bucal. Es importante recordar que a esta patología se la conoce como «la gran simuladora», y que las lesiones bucales tienden a confundirnos con otro tipo de lesiones. El diagnóstico precoz en conjunto de un tratamiento oportuno puede evitar la transmisión de la enfermedad y así prevenir sus complicaciones.
A Comparative Study of Conventional Steel Building and Pre-Engineered Steel Building Structure using STAAD PRO
Authors: Kumar Neeraj , Grover Dr. K. S.
Published: June 2022

Abstract: Steel is generally used in all the industrial structures. The design of Pre-Engineered Building structures using tapered sections as the primary frames has saved quantity of steel substantially when comparing to the steel used on Conventional Steel Building structures. In this study, industrial building of different spans (10m, 15m, 20m, 25m, 30m, 40m & 50m) is analysed and designed according to the Indian Standards, IS 800-2007 using conventional hot rolled sections and PEB tapered sections. In this study, a relation is being made among the parameters of building to get the flow of pattern of steel reduction in the primary frames of different spans of structures. This study is carried out using STAAD PRO Connect edition. Keywords: Pre-Engineered Building, Conventional Steel Building, STAAD Pro, IS 800-2007, Tapered Section
Bond Length and Bond Length Distortion in Zn-Series of II-VI group of Semiconductors
Authors: Singh Kalyan , Singh V. K. , Sharma P. K.
Published: June 2022

Abstract: Semiconductors are present periodic table of group II-VI, in this paper, impurities doped with Be-series, Zn-series and Cd-series such as BeS, BeSe, BeTe, ZnS, ZnSe, ZnTe and CdS, CdSe, CdTe. The value of distorted bond length found corresponds with orbital parameter, covalence, empirical parameter and hybrid energy used as input data. Keywords: Semiconductors, bond length, impurity atom and host atom.
Design Approach For Failure Detection Of Connecting Link Of Electric Overhead Traveling Crane Employed In Vigour Metal & Alloy, Butibori, Nagpur, Maharashtra
Authors: Khambalkar Vicky , Handa Chandrahas , Ninawe Abhinav
Published: June 2022

Abstract: This paper gives the design approach for failure of connecting link at keyway for electric overhead traveling crane. Failure of connecting link occurs in electric overhead traveling crane which is presently equipped in Vigour Metals and Alloy, MIDC Butibori, Nagpur, Maharashtra, India. The capacity of electric overhead traveling crane is 5 Tons. Within this work, as per problem identification in same industry, an approach of failure analysis for critical part of crane had been carried. In this paper, discussion of the torque, maximum shear stress, equivalent shear stress, shear stress, bending stress, bending moment, twisting moment, forces, etc., which are induced in connecting link while performing some operation or loading and unloading of materials or containers have done. To identify and minimize this failure occurs in connecting link, detail literature search and analytical treatment is carried. Keywords: Connecting link, keyway, electric overhead traveling crane, shear stress, torque, bending moment, failures, design approach, etc.
Disease Prediction using Machine Learning
Authors: Chaube Neha , Mansuri Fahad , Sonkar Kavya , Singh Shruti
Published: June 2022

Abstract: Technology has altered the health arena to a large extent in this era of IT. The goal of this research is to create a diagnosis model for a variety of diseases based on their symptoms. To create such a model, this system used data mining techniques such as classification. The intelligent agent is trained using datasets containing copious data regarding patient diseases that have been gathered, refined, categorised, and utilised. K-Fold cross-validation is used to evaluate the machine learning models after splitting the data. For cross-validation, employed are the Support Vector Classifier, Gaussian Naive Bayes Classifier, and Random The patient might then contact the doctor for further therapy based on the results. It's an example of how technology and medical expertise are flawlessly woven together with the goal of achieving "prediction is better than cure." Keywords: Gaussian Naive Bayes classifier, K-cross validation, Random forest classifier, Support vector classifier, medical data, classification, data mining.
Secure Message Transmission Using Centralized Group Key Distribution Protocol
Authors: Vetrivel P , Gopiya M , Sangareswari S. , Karpagajothi B.
Published: June 2022

Abstract: In the secure message transmission, transmitted information can only receive by the authorized group members. To achieve a secure communication, symmetric key (group key) is used to both encrypt and decrypt the information, that shared among the group members. This paper, proposes an efficient centralized group key management scheme (GKDP) for achieving a secure multicast communication between the group members that reduces the cost of computation of SERVER(S) and rekeying cost of group members. The group key (GK) generated in the multicast network is securely distributed with the help of the RSA cryptosystem. Whenever the new member joins the group, computation cost of S reduced by performing single addition, multiplication and encryption, for updating the group key (GK). Whenever the member leaves the group, S performs single subtraction, division and encryption, for updating the group key (GK). By comparing with existing group key management protocol, the proposed protocol has significantly reduced computation complexity and rekeying cost. The proposed protocol is tested on star topology, the test results compared with existing group key management protocol. The comparison results show that the proposed protocol is efficient in terms of reducing the computational complexity of S and rekeying cost of group members. Index Terms: Secure multicast, rekeying cost, computational complexity, centralized group key management.
Remote Vehicle Control through Cell Phone Using DTMF
Authors: Naveena M.
Published: June 2022

Abstract: The aim of the proposed project is to use a mobile phone to drive a car. The project necessitates the use of two mobile phones, one to control the robot and the other to deliver DTMF signals to the robot vehicle. The commands are received by a DTMF decoder connected to an 8051 microcontroller, which then controls the vehicle movement with the help of a motor driver. Thus, with the motor driver IC, two DC motors enable vehicle movement based on commands supplied from the phone. The power source is a battery. New technologies can be implemented using a robotic vehicle. The Dual Tone Multi Frequency (DTMF) system is utilised to control the robot. In everyday life, DTMF technology can be valuable. To this generation, DTMF technology is unrivalled. The science of Digital Signal Processing underpins DTMF technology. Previously, a Radio Frequency circuit was employed for wireless control, but it had a significant disadvantage in terms of range. As a result, it restricts control and has a negative impact on the vehicle's performance. DTMF, on the other hand, transforms this deprivation of the Radio Frequency circuit into domination. It gives you a wider range of options for working and produces better results. The phone in the microcontroller is used to operate and maintain this system. The remote handling operation of a robot using Dual Tone Multi Frequency is referred to as wireless communication. Keywords: Dual Tone Multi Frequency, Voltage Regulator, Microcontroller, Cell phone, Motor Driver, DC Motor
A Comparative Study of Antidiabetic Activity of Azadirachta Indica, Aloe Vera and Allium Cepa
Authors: Das Rajesh Kumar
Published: June 2022

Abstract: Extract from medicinal plants are widely used to prevents various diseases due to presence of lots of phytochemicals. The extracts from different parts like leaf, stem, fruit, flower, bark, root of Azadirachta indica, Aloe vera and Allium cepa shows lots of pharmacological activity. Antidiabaetic property is most important of them. Various parts of Azadirachta indica, Aloe vera and Allium cepa were largely used in Ayurveda, Unani and Siddha medicines. Chemical investigation on all three plants explore the presence of different types of active compounds like azadirachtin , nimbolinin, nimbin, nimbidin, nimbidol, sodium nimbinate, gedunin, salannin, and quercetin from Azadirachta indica, enzymes, minerals, sugars, lignin, saponins, salicylic acids, amino acids and vitamins like vitamins A (beta-carotene), C and E, vitamin B12, folic acid, and choline from Aloe vera and Cyaniding glycosides, Prostaglandins, quercetin, flavonoids, Sterols, Phenol compounds, Catechol and Protocatechuic acid from Allium cepa. This review explore the details of traditional use, phytochemicals and comparative studies of antioxidant and antidiabetic properties among lots of pharmacological properties of Azadirachta indica, Aloe vera and Allium cepa. Keywords: Azadirachta indica, Aloe vera, Allium cepa, Antidiabetic property, Quercetin.
Visible Light Communication for Vehicle Monitoring
Authors: Mohamed S Azhar , J Gnaneshwaran , G S Jagan
Published: June 2022

Abstract: High number of accidents had been placed all over the world due to the collision between automobile vehicles. According to the report of the world health organization (WHO), road traffic crashes results in the death of approximately 1.3 million people around the world each year with non-fatal injuries. Therefore, vehicle and people safety are very important. The idea is to propose of reducing the accidents in our daily lives and to avoid accident between vehicles. This involves arresting the human errors and technical failures of vehicles in prior. The hazardous situation can be overcome if there is a proper communication protocol used in all vehicles and depending upon the driver’s position controls. There are various vehicular methods and protocols are available. These radio frequency (RF) based communication ideas have some limitations i.e. data interference, spectrum break and security issues. These drawbacks can be overcome by using Visible Light Communication. This produces high frequency bandwidth, standard security, interference reduction and high speed data rate. Visible Light Communication is a data communication system which uses visible light for high rate data transmission and receiving operation. This method of technology is called as Light Fidelity (Li-Fi). Through this proposed system, it will slow down the vehicle and gives an alert to the driver also it gives an emergency stop. Even though an accident occurs, SMS will be sending along with location to Public service provider. This presents the highly accurate method to avoid accidents between two vehicles. Keywords: Li-Fi safety, Accident detecting and alert system, Automatic flagging system, Emergency stop system.
Analysis of Benefits of E Payment System to Customers in a Pandemic Situation with Special Reference to Alappuzha
Authors: S Ramseena
Published: June 2022

Abstract: The world has been moving towards all things electronically. It happened with the lockdown coming into effect, especially for electronic payments in India. So this research is to study the benefits of e-payment to customers and the major problems faced by them. The objective of the present study was accomplished by conducting a descriptive research. In this study both primary and secondary data was used.The approach adopted in the study is survey approach. The main techniques used for this study is questionnaire. In this study sample unit is commoners who use online payment. The samplingarea is restricted to Alappuzha district. The data collected for this study was analysed using simple percentage analysis. It found that most of them prefer online payment because of the various benefit it offers. Majority of them use Google pay as their payment platform and mobilebanking as their payment gateway. It found that the major factors which backed them from opting online payment were security, privacy, theft and fraud. When the respondents were asked about their internet access only a least of them had no access, rest have internet access either at home or at work place. In order to improve security most of them suggested to turn two factor Authentication. Key words: E Payment, COVID 19, Google pay, Internet
5-in-1 Automatic Agriculture Machine
Authors: Killampalli Rohit , Nagaraju Thirunahari , Naidu Valluru Rajendra , Prasad4 L. V. R Chaitanya
Published: June 2022

Abstract— Goal of this project is to complete five important tasks in the world of agriculture, including 1 – seed planting automation, 2 – weed plucking mechanism building, 3 – plough mechanism control, 4 – providing water where seed is sown, and 5 – soil leveling. All of these mechanisms are connected to a single moving mechanism, and the tasks listed above will be carried out in order. The entire apparatus is meant to be automated and controlled by a remote. The moving mechanism is controlled by a remote control unit that uses RF modules to move in all directions. Initially, this device must be positioned from the row's beginning point, where seeds will be sown one after the other with a predetermined spread. After placing the mechanism, the start button must be pressed, causing the mechanism to travel a short distance ahead before stopping to drop the seeds. After completing this task, the mechanism will be moved farther to supply the water. The mechanism will be halted for a short time while supplying water again, however the mechanism will continue to drop seeds and give water until the stop button is pressed. Keywords—Control keys, DC Motor, Ploughing mechanism, RF Module, Seed planting mechanism, Soil leveling mechanism, Solenoid coil, Vibrating Motor, Water delivering mechanism, Weed plucking mechanism.
Earth Tube Heat Exchanger
Authors: Kumawat Siddhanth , Khatik Ghanshyam
Published: June 2022

Abstract: Devices that utilise the ground as a wellspring of or sink for warming or cooling are called ground-to-air heat exchangers, ground pipe heat exchangers, or soil heat exchangers. Numerous concepts and experiments with EAHE have so far been developed and tested to determine the best parameter values to increase performance based on location and other variables. In this study, we will review the studies conducted so far from the viewpoint of performance evaluation considering the influence of various parameters such as construction materials, depth from the ground surface, wind speed, and pipe length.
Home Automation System Using Internet of Things
Authors: Nawaz Khan Ansar , Nawaz Siraj
Published: June 2022

Abstract: With advancement of Automation technology, life is getting simpler and easier in all aspects. In today’s world Automatic systems are being preferred over manual system. With the rapid increase in the number of users of internet over the past decade has made Internet a part and parcel of life, and IOT Is the latest and emerging internet technology. The advantages of IOT home automation system is there is less man power or only need the some hardware or an one mobile application which is connected to the hardware we have developed the system using raspberry pi we have to develop a home automation system that interfaces with Android mobile devices. The mobile device and system can communicate with each other via Wi-Fi. The mobile application can be loaded and interfaces with system from any compatible device. Commands to ON/OFF electrical equipment like lights, fans, air conditioners etc. This is very useful for the person who is away from the home because he handle his appliances using application. We can switch on off our home appliances anywhere in geographical locations. Keywords: Raspberry Pi , cloud , mobile app, home automation, internet of things,
Analysis of Argumentation Form Changes in High School Students' subject inquiry essays
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Jeong Da-Un
Published: June 2022

Objectives The purpose of this study is to understand the change in argument form through the results obtained after applying the subject inquiry essay to actual school classes.
Methods To this end, a subject inquiry essay was conducted on 30 first grade high school female students sampled through the stratified random sampling method, and the argument format of the resulting essay text was analyzed. The students' essay texts were analyzed with frequency and correlation using the SPSS 28.0 program, establishing an analysis frame and analysis criteria based on whether or not the 4th level components of the OREO Map were included.
Results The results are as follow. First, the subject inquiry essay showed differences according to the argument form elements. Second, it was confirmed that subject inquiry essay represents a stage with a high level of argumentation form. Third, in the learning of the argument form according to the session, it was found that the components of the argument form increased from the first to the third session. Fourth, it was found that the level of argumentation significantly improved in the learning of the argument form for each session. That is, subject inquiry essay is effective in the development of argument form elements and the development of argument form elements and levels according to the session. This suggests that subject inquiry essay is effective in learning argumentation form. In addition, although there was a difference in the correlation between elements of the argument form, it was found that the correlation of elements of the argument form improved as the number of sessions increased.
Conclusions The results of this study will serve as a basic study to confirm the effect of argumentation-form learning in subject inquiry essays.