bluuebunny/crossref_metadata_2025 huggingface dataset:
Is aromatic terpenoid composition of grapes in Northwestern Iberian wine cultivars related to variation in VviDXS1 gene?
Authors: Royo Carolina , Carbonell-Bejerano Pablo , Torres-Pérez Rafael , Freire Luisa , Ibáñez Javier , Martínez-Zapater José Miguel , Vilanova Mar
Published: February 2021

BACKGROUND:

Monoterpenes and C13-norisoprenoids are key terpenoid compounds for wine aroma. The enzyme encoded by VviDXS1 participates in terpenoid biosynthesis in grapevine fruits and gain-of-function mutations in this gene lead to characteristic muscat aroma.

OBJECTIVE:

To assess for VviDXS1 contribution to aroma variation in Northwestern Iberian wine cultivars, we resequenced this gene in 111 cultivars and compared grape juice terpenic composition in 12 of them.

METHODS:

VviDXS1 was capture-targeted for resequencing with Illumina paired-end reads, SAMtools was used for variant calling and gene haplotypes were reconstructed with PHASE. Monoterpenes and C13-norisoprenoids were quantified in free and glycosidically-bound forms from grape juice by gas chromatography-mass spectrometry.

RESULTS:

Terpenic composition discriminated between muscat, terpenic and neutral profiles across cultivars. While the terpenic profile of Loureira and Albariño white cultivars was not associated with muscat-like mutations, Albariño carries a V34L substitution in VviDXS1 that is also present in other aromatic cultivars and was not reported before. Tempranillo and Cabernet Sauvignon red cultivars accumulated higher levels of C13-norisoprenoids, which was not associated with specific variation in VviDXS1.

CONCLUSIONS:

Apart from the uncharacterized substitution present in Albariño, findings suggest that terpenoid pathway-related genes other than VviDXS1 could contribute to the aromatic attributes of these cultivars.
Natural diversity in health related phytochemicals in Turkish tomatoes
Authors: Bakir Sena , Capanoglu Esra , Hall Robert D. , de Vos Ric C.H.
Published: February 2021

BACKGROUND:

Tomatoes are important fruits in the Mediterranean diet and are considered to reduce the risk of different human diseases due to their antioxidative powers.

OBJECTIVE:

The purpose of the present study was to investigate the biodiversity within a set of 50 tomato fruit accessions collected across Turkey concerning their antioxidant capacities and the levels of potential health-beneficial compounds including phenolic compounds, carotenoids, ascorbic acid and tocopherols.

METHODS:

All accessions were simultaneously grown in an open experimental field in 2017 and ripe fruits were harvested for analysis. Antioxidant capacities of both hydrophilic and lipophilic extracts were determined using spectrophotometric assays after which individual antioxidants were identified by HPLC using an on-line antioxidant detection system. Phenolic acids, flavonoids, carotenoids and vitamins C and E were quantified using HPLC.

RESULTS:

The results indicated that there is a wide diversity within this small collection with respect to their hydrophilic and lipophilic antioxidants.

CONCLUSION:

Hydrophilic antioxidant capacity of the tomatoes was generally related to chlorogenic acid and Vitamin C levels, while lipophilic antioxidants were correlated to all-trans lycopene.
Global Perspective on Telemedicine for Parkinson’s Disease
Authors: Shalash Ali , Spindler Meredith , Cubo Esther
Published: February 2021

Telemedicine programs are particularly suited to evaluating patients with Parkinson’s disease (PD) and other movement disorders, primarily because much of the physical exam findings are visual. Telemedicine uses information and communication technologies to overcome geographical barriers and increase access to healthcare service. It is particularly beneficial for rural and underserved communities, groups that traditionally suffer from lack of access to healthcare. There is a growing evidence of the feasibility of telemedicine, cost and time savings, patients’ and physicians’ satisfaction, and its outcome and impact on patients’ morbidity and quality of life. In addition, given the unusual current situation with the COVID-19 pandemic, telemedicine has offered the opportunity to address the ongoing healthcare needs of patients with PD, to reduce in-person clinic visits, and human exposures (among healthcare workers and patients) to a range of infectious diseases including COVID-19. However, there are still several challenges to widespread implementation of telemedicine including the limited performance of parts of the neurological exam, limited technological savvy, fear of loss of a personal connection, or uneasiness about communicating sensitive information. On the other hand, while we are facing the new wave of COVID-19 pandemic, patients and clinicians are gaining increasing experience with telemedicine, facilitating equity of access to specialized multidisciplinary care for PD. This article summarizes and reviews the current state and future directions of telemedicine from a global perspective.
A Validation Study of PROMIS Sleep Disturbance (PROMIS-SD) and Sleep Related Impairment (PROMIS-SRI) Item Banks in Individuals with Idiopathic Parkinson’s Disease and Matched Controls
Authors: Jones Jolynn , Nielson Spencer A. , Trout Jonathan , Swenson Mckaella , Reiley Joseph , Tanner Jared , Bowers Dawn , Kay Daniel B.
Published: February 2021

Background: Parkinson’s disease (PD) is associated with sleep disturbance (SD) and sleep-related impairment (SRI). Validation of self-report measures of these problems is needed in PD. The Patient-Reported Outcomes Measurement Information System (PROMIS) includes tools that assess these problems (PROMIS-SD and PROMIS-SRI, respectively). Objective: This study aimed to further validate these measures in individuals with PD and matched controls. Methods: Individuals with early-stage PD (n=50) and matched controls (n=48) completed measures of SD including the PROMIS-SD, Pittsburgh Sleep Quality Index (PSQI), and Insomnia Severity Index (ISI). They also completed measures of daytime impairment including the PROMIS-SRI, Epworth Sleepiness Scale, State-Trait Anxiety Inventory, Beck Depression Inventory 2nd edition, and Parkinson’s Disease Questionnaire-39. Internal consistency for the PROMIS measures were assessed using Cronbach’s α coefficient and item-total correlations in the total sample. Convergent and divergent validity of the PROMIS item banks were assessed using Spearman correlations. Results: The PROMIS item banks had excellent internal consistency (α>0.94). Supporting convergent validity, the PROMIS-SD had strong correlations with other measures of SD (ρ>0.68, for PSQI and ISI) and the PROMIS-SRI had moderate to strong correlations with all measures of daytime impairment (ρ=0.41–0.72). Supporting divergent validity within the PD group, the PROMIS-SD correlated more strongly with SRI than with the Parkinson’s Disease Questionnaire total score, a metric of PD related impairment. Conclusion: In middle-aged and older adults, with and without early-stage PD, the PROMIS-SD and PROMIS-SRI are reliable and valid measures of SD and SRI, respectively.
In the pursuit of equity: COVID-19, data and Aboriginal and Torres Strait Islander people in Australia
Authors: Griffiths Kalinda , Ring Ian , Madden Richard , Pulver Lisa Jackson
Published: February 2021

Since March 2020 in Australia, there has been decisive national, and state and territory policy as well as community led action involving Aboriginal and Torres Strait Islander people as information about COVID-19 arose. This has resulted in, what could only be framed as a success story in self-determination. However, there continues to be issues with the quality of data used for the surveillance and reporting of Aboriginal and Torres Strait Islander people during the pandemic. This article discusses some of the important events in pandemic planning regarding Aboriginal and Torres Strait Islander people and how this relates to surveillance and monitoring in the emerging and ongoing threat of COVID-19 within Aboriginal and Torres Strait Islander communities. The authors also identify some of the data considerations required in the future to monitor and address public health.
Nfatc1 and Tumor Associated Macrophages Affect Progression of Certain Subsets of Diffuse Large B Cell Lymphoma Non-Gcb Subtypes
Authors: Murti Krisna , Muslina Muslina , Kartika Ika , Hidayat Rachmat , Amalia Ella
Published: February 2021

A B S T R A C TIntroduction Diffuse large B cell lymphoma (DLBCL) is the most common type ofnon-Hodgkin lymphoma among B cell lymphomas. The interaction of tumor cellswith their microenvironment (tumor microenvironment, TME) leads to progressivityof malignancy. CD163 + macrophages known as components of TME. Nuclear factorof activated T cell (NFATc1) and MYC are important transcription factors inmalignant transformation and progression. Therapeutic strategies were fastdeveloped, nevertheless, efforts to decrease DLBCL morbidity and mortality areunsatisfied, therefore,new markers for prognosis and or therapeutic options of thepatients are necessary. This study was aimed to investigate NFATc1 expression inDLBCL and its TME. Methods: Thirty-two paraffin blocks were selected thenimmunostained for expression of NFATc1, MYC, and CD163. Clinopathologic datai.e. ages, gender, and proliferation index Ki-67 were obtained. Data was analyzedby statistics Result: Positive expression of CD163 and NFATc1 was among 55%and 45% of cases respectively. All DLBCL cases in this study were non-GCBsubtype and more patients were under 60 years (66%). Positive expression ofCD163 was higher in males (69%) and in patients under 60 years (63%). Tissuespositive for both NFATc1 and CD163 was observed higher among males andpatients under 60 years. Conclusion: NFATc1 may affect development and orprogression of certain subsets of DLBCL non-GCB subtype.
The Potential of CO2 Incubator "Sriwijaya CO2 Incubator" Against Cell Culture Proliferation In Invitro Study As Smart Controlling-Based CO2 Incubator For Cell Culture
Authors: Wardiansyah  , Rachmat Hidayat  , Msy Rulan Adnindya
Published: February 2021

A B S T R A C TIntroduction. A CO 2 incubator is an essential tool for the initiation of theproliferation of primary culture cells or cell lines. In principle, this tool works bykeeping the sample cell line at an optimum temperature of 37 o C and 5% carbondioxide supply. The ability of the CO 2 incubator to maintain temperature and supplyof 5% carbon dioxide are essential points in the development of the CO 2 incubator.This study is an attempt to convince the potential of Sriwijaya CO 2 Incubator inmaintaining the proliferation ability of cultured cells in an in vitro study. Methods.This study is an experimental pre-post test that explores the percentage of viabilityof primary culture cells (fibroblasts) before and after incubation in CO 2 incubators.The object of this study was fibroblast cells obtained from the prepuce of patientswho performed circumcision. Results. Fibroblast cell proliferation in CO 2 incubatorsshows an increase in the number of fibroblast proliferation which can be seen withthe increasing number of cells visualized by inverted microscopy. Conclusion.Sriwijaya CO 2 incubator has the potential to be used in in vitro research to triggerthe growth and proliferation of fibroblast cells.
The Substitution of Corn Silage with Potato Pulp Silage at Differing Level in Dairy Cows on Milk Yield, Composition and Rumen Volatile Fatty Acids*
Authors: ŞENYÜZ Hasan Hüseyin , KARSLI Mehmet Akif
Published: February 2021

The aim of this study was to determine the quality of potato pulp silage (PPS) prepared with wheat bran and barley straw and the effects of the substituting corn silage with potato pulp silage at differing levels in dairy cows on milk yield, composition and rumen volatile fatty acid (VFA). The study consisted of two experiments. Nutrient con-tents, fermentation parameters, in situ organic matter (OM) and starch degradabilities, in vitro digestibility (IVD) and metabolic energy (ME) content of PPS were determined in the first experiment. The effects of substituting corn silage with potato pulp silage at 0%, 15%, 30% and 45% in the diet of lactating 12 dairy cows on feed intake, milk yield, milk components, rumen fermentation parameters were evaluated in the second experiment. While dry matter (DM), OM and crude protein (CP) contents, pH of silages were statistically similar, starch content, in vitro organic matter digesti-bility (IVOMD), ME, net energy lactation (NEL), and lactic acid values were significantly higher in PPS compared with corn silage (P<0.05). Organic matter intake, milk yield, the composition of milk, post-feeding pH and total VFA levels of ruminal fluid at all sampling hours were similar among the dairy cows (P>0.05). It was concluded that; PPS prepared with wheat bran and straw had a very good silage quality and were even better than corn silage (control). Substitution of corn silage with PPS up to 45% did not cause any negative effects on rumen fermentation parameters and can be safely substituted with corn silage up to 45% in dairy cow diets.
Türkiye’de Yetiştirilen Holştayn Melezi Sığırlarda BLAD ve FXID Hastalıklarının Araştırılması
Authors: AKSEL Esma Gamze , DALDABAN Fadime , ARSLAN Korhan , KEÇELİ Hasan Hüseyin , AKYÜZ Bilal
Published: February 2021

Bu çalışmada Türkiye’deki Holştayn melezlerinde Sığır Lökosit Bağlanma Eksikliği (BLAD) ve Faktör XI Eksikliği (FXID) kalıtsal hastalıklarına sebep olan mutant allellerin varlığının araştırılması amaçlanmıştır. Çalışmada toplam 48 baş sığır incelenmiştir. Yapılan moleküler analizlerden sonra incelenen melez sığırların birinin BLAD taşıyıcısı olduğu, FXID taşıyıcısı bireye rastlanılmadığı görülmüştür. Bu çalışma ile bu kalıtsal hastalıkların görüldüğü saf Holştayn ırkı dışında da BLAD ve FXID’ne sebep olan mutant allellerin varlığı araştırılmıştır. Böylece saf Holştayn ırkının haricinde de BLAD’a sebep olan mutant allelin varlığı ilk kez gösterilmiştir. Çalışma sonunda özellikle ıslah ve çevirme melezle-melerinde baba hat olarak kullanılacak damızlıkların, önemli kalıtsal hastalıklardan ari olduklarının kontrol edilmesi gerektiği sonucuna varılmıştır. Eğer bu konuda gerekli özen gösterilmez ise daha önce ırka özgü olduğu bilinen kalıtsal hastalıklara (BLAD, FIXID vb.) sebep olan mutant allellerin diğer sığır ırklarına da yayılabileceği sonucuna varılmıştır.
Acil Veteriner Hekimliğinde Ultrasonografik Muayene Yöntemleri
Authors: ŞENGÖZ ŞİRİN Özlem , FİDAN Mehti , BUMİN Ali
Published: February 2021

Bu derlemede travmada sonografi ile abdomen odaklı değerlendirme (AFAST), travmada sonografi ile toraks odaklı değerlendirme (TFAST) ve başucu akciğer ultrasonografik değerlendirme (VetBLUE) yöntemleri ele alınmıştır. Ultrasonografik muayeneyi gerçekleştirecek hekimin çok detaylı olmasa da belirli bir seviyede anatomi bilmesi ve kul-landığı cihazın modlarına hakim olması gerekmektedir. Bunun dışında muayene teknikleri için yaklaşık 3 ile 6 dakika gibi kısa bir zaman yeterli olmaktadır. Ultrason birçok yardımcı tanı aracının aksine non–invazif güvenli ve daha hızlı bir yöntemdir. Çoğu araştırmacı bunun üzerine giderek acil kliniklerinde ultrason kullanarak hayati önem arz eden vakalar-da hem hastanın zaman kaybını azaltmak, hem de hekimin daha kolay bir şekilde belirli hastalıkları elimine etmesini sağlayan birçok muayene tekniğinin geliştirilmesine yardımcı olmuştur.
Neuronal Lipofuscinosis in a Hairy Goat
Authors: AVCI Hamdi , BİRİNCİOĞLU Sümbül Serap , EPİKMEN Erkmen Tuğrul , AYDOĞAN Ahmet
Published: February 2021

In the present case, neuronal lipofuscinosis was determined in a three-year-old female hair goat. The sys-temic necropsy was performed. Tissue sections were stained with hematoxylin and eosin (HE), periodic acid schiff stain (PAS), Schmorl’s and long Ziehl-Neelsen (ZN) methods for lipofuscin; Turnbull’s blue method for hemosiderin and melanin removal method II for melanin. Unstained deparaffinized sections were examined microscopically for fluores-cence in transmitted ultraviolet light. In addition, samples of pons and medulla oblongata were collected and processed for transmission electron microscopy investigations. Macroscopically, the meninges were opaque and the cerebral hemispheres had firm consistency. Microscopically, pigment granules in varying intensity were observed in the cytop-lasm of the neurons of the pons and medulla oblongata. Red or yellowish-brown grannules were usually seen in peri-nuclear localization, and filled all cytoplasm of some neurons. Moreover, meningeal and perineuronal edema, perivas-cular hemorrhage and neuronal degeneration were prominent histopatologic findings. The granules were positively stained with PAS, Schmorl’s and long ZN methods, but negatively stained with Turnbull’s blue method and melanin removal method II. Pigments found in all affected neurons were brightly autofluorescent. Electron microscopy also confirmed that the pigment granules were lipofuscin.
INTERNATIONAL COMPETITIVENESS OF THE AGRO-INDUSTRIAL SECTOR OF UKRAINE IN TERMS OF MODERN ECONOMIC GLOBALISATION
Authors:   Prydniprovska State Academy of Civil Engineering and Architecture, Chala Veronika , Barbul Ye. S. ,   Prydniprovska State Academy of Civil Engineering and Architecture
Published: February 2021

The competitiveness of the agro-industrial sector should be considered as a fairly broad concept that characterizes the ability to compete in both domestic and foreign markets and is measured by the degree of presence of domestic products in them. The agro-industrial complex of Ukraine is one of the key components in the process of solving certain socio-economic problems. Domestic farmers have significant potential for development, the implementation of which requires addressing a number of obstacles. Despite the fact that Ukraine is one of the leaders in the export of agricultural products to the international market, in the future the development of the domestic agricultural sector may face significant problems due to low technology, insufficient inflow of investment resources, lack of highly qualified specialists in the industry. The article examines the prospects for the development of the domestic agro-industrial complex in the context of European integration. Ukrainian agricultural producers have a strong resource base for short-term capitalization and development of agricultural production, at the same time, agricultural enterprises are producers of raw materials, not finished products for consumption. Therefore, the efficiency of enterprises depends on the redistribution of income at all stages of value added. Reducing the cost of raw materials directly proportionally affects the profitability of production and efficiency of enterprises. The purpose of this article is to identify problems and prospects of agricultural entrepreneurship in Ukraine, and provide proposals for sustainable development of agriculture. The authors got acquainted with the mechanism of assessing the competitiveness of the enterprise and developing ways to increase competitive positions in the foreign market. The transformation of the agricultural sector of Ukraine is due to current trends, primarily in the world market. The integration of Ukrainian society into the European community encourages and forces domestic producers of the agricultural sector to produce products that are highly efficient and competitive, as the requirements for the quality characteristics of finished products increase.
ANALYSIS OF THE EUROPEAN EXPERIENCE IN USING THE SYSTEM OF THE ECOLOGICAL SECURITY IN SUSTAINABLY-DEVELOPED CITIES
Authors:   SO «V. Mamutov Institute of Economic and Legal Research of NAS of Ukraine», Melnykova Maryna , Gradoboieva Yelyzaveta ,   SO «V. Mamutov Institute of Economic and Legal Research of NAS of Ukraine»
Published: February 2021

The article examines and summarizes the experience in using the components of the ecological security system in European cities, which ensure the solution of problems concerning sustainable development. The research used the methods of a systematic approach, analysis and synthesis, abstraction, logical generalization. The city's ecological security system is a set of economic methods and legal tools linked by the tasks of protecting the environment and creating comfortable living conditions for the population. Based on considering conditions and factors, the above methods and tools allow making decisions on supporting the ecologically safe development of the city. The experience of sustainably- developed European cities shows that their main ecological priorities at the present stage are the following: developing renewable energy; improving the energy efficiency of buildings and structures, reducing urban motor vehicle traffic in the central part of the city, using bicycles and urban electric transport; forming green spaces in order to strengthen ecosystem resilience and preserve biodiversity; rational handling of industrial and household waste. To achieve these priorities the following methods and tools are used: the development of a circular economy; introduction of resource-saving technologies and environmental innovations; formation of the ecological consciousness of the population; the broad powers of local governments in the environmental sphere, implementation of ecological programs and projects; support for environmental entrepreneurship. It was determined that to use the European experience of the ecological security system in Ukrainian cities, it is necessary to carry out preparatory work in the legal aspect (implementation of legislation and development of regulations, standard acts, provisions) as well as in the organizational and economic aspects (formation of conditions and opportunities for the implementation of decisions made in the environmental sphere). The preposition is made that the introduction of the individual components of the ecological security system used in European sustainably-developed cities should be done in Ukraine gradually, starting with eco-projects, eco-entrepreneurship, eco-cooperation and the formation of eco-spaces. The above components of the ecological security system must be aligned with goals and priorities of the sustainable development of the city in the economic and social aspects, which should be the subject of further research.
THE CHOICE JUSTIFICATION FOR INTERNATIONAL PRODUCTION COOPERATION FORMS: TECHNOLOGICAL AND INTEGRATION ASPECTS
Authors:   University of Customs and Finance, Nebaba Natalia
Published: February 2021

The relevance of the research topic is determined by the essential nature of the world labor division's influence on the social production organization and the international economic relations trade parameters. The theoretical substantiation and approaches development for generalizing the essence and choosing industrial cooperation forms in international economic relations have been considered the research's purpose. The prerequisites for the production and technological connectivity emergence between the creating new value cooperative chain participants have been generalized. The specific nature of the economic cooperation forms content has been established. This content's essence is based on the contradictory intertwining of different socio-economic landmarks of the cooperation participants. The necessity of considering the specifics of economic content and features of the mechanism of long-term cooperation and differentiation of levels of participants' economic potential in partnership in justifying the choice of forms of international industrial cooperation is proved. The interconnection and interdependence of economic integration and production cooperation in international economic relations have been defined by taking into account the current level of business dependence and administrative coordination of various partnership entities' activity plans. The ambiguous essence is revealed, the consequences of using the toll raw materials in the international production and cooperation relations operations have been revealed. The positivity of the economic integration global aspect manifestation in international industrial cooperation has been proved by the cooperation structural and organizational forms significant expansion. The core and system-forming nature of the cooperative relation participants' unity level influence on choosing international production cooperation form have been revealed. The characteristics of international production cooperation structural and organizational forms such as cluster formations, business incubators, industrial parks, technology parks, innovation centers have been provided.
Verso un'infrastruttura materiale e immateriale per la Bioregione
Authors: Dezio Catherine
Published: February 2021

L'idea bioregionale sottende un progetto di ricomposizione dei paesaggi di bordo che, ripristinando flussi, funzioni ecologiche, relazioni e identità, realizza un tessuto connettivo e attivatore. Tale tessuto agisce tramite interventi locali, caratterizzati da strumenti e linguaggi multidisciplinari e transcalari. Secondo quest'ottica, gli spazi rappresentano entità che si attivano attraverso una dimensione relazionale, di natura sociale, politica, economica, culturale, dai risvolti spaziali. Pratiche di modificazione, forme di regolamentazione, politiche di governo, gesti e usi, immaginari urbani e rurali concorrono, in forma plurale, alla generazione di spazi che sono il prodotto di questa molteplicità. È, quindi, attraverso questo quadro bioregionale che possiamo rileggere spazi, azioni progettuali e relazioni come elementi di una rete.
Nello spazio periurbano della metropoli estesa: piano e progetti per Romano di Lombardia
Authors: Alì Alessandro , Lanzani Arturo
Published: February 2021

Il caso di Romano di Lombardia, a cavallo tra le province di Bergamo, Brescia e Cremona, racconta del tentativo di un piccolo centro di costruire un percorso di rilancio e valorizzazione in controtendenza alla visione di sviluppo oggi prevalente all'interno dei territori periurbani della megalopoli padana. L'integrazione di piano e progetti, l'attenzione rivolta alla salvaguardia della risorsa ‘suolo inedificato', la centralità della ricomposizione e della manutenzione straordinaria delle infrastrutture cittadine a supporto della qualità della vita quotidiana costituiscono i caratteri salienti di una vicenda urbanistica particolarmente densa, in corso dal 2016. Il tentativo di costruire una prospettiva di equilibrio e non più di crescita dell'urbanizzato si scontra tuttavia con evidenti difficoltà, il cui superamento richiede un radicale cambiamento di rotta del fare urbanistica.
Urbanistica e commercio: indagini e contributi strategici per Romano di Lombardia
Authors: Limonta Giorgio , Tamini Luca
Published: February 2021

Nell'ambito del processo di redazione del Documento di piano del Piano di governo del territorio del Comune di Romano di Lombardia, il Laboratorio Urb&Com del Politecnico di Milano ha curato la redazione della componente commerciale, definendo il quadro conoscitivo di contesto e proponendo linee strategiche per lo sviluppo della rete locale. Questo contributo ricostruisce i principali elementi analitico-progettuali emersi durante l'esperienza di ricerca, descrivendo le specificità e le peculiarità del contesto commerciale sovralocale e regionale di riferimento con le quali è stato necessario confrontarsi per la definizione delle scelte strategiche del nuovo strumento urbanistico.
Arco Blu. Il paesaggio oltre i confini come strategia di ricomposizione territoriale
Authors: Longo Antonio
Published: February 2021

La partecipazione a un bando competitivo per progetti di miglioramento del capitale naturale ha offerto l'occasione per avviarne uno nella bassa pianura bergamasca che travalicasse i confini dei singoli comuni, sperimentando nuove modalità di governo. Denominato Arco Blu, fondato su un approccio pragmatico, consiste nella ricomposizione di un insieme di progetti locali di riqualificazione ambientale, da adattare e integrare sulla trama di un disegno territoriale e paesaggistico d'insieme che attraversa e connette le valli fluviali. La parcellizzazione iniziale degli interventi diviene quindi il punto di avvio del progetto, che per integrarli li modifica ed estende, coinvolgendo e responsabilizzando le singole amministrazioni. Si tratta di un progetto collaborativo che punta sia a conseguire risultati immediati, sia a creare le condizioni per una visione coerente di lungo periodo.
Romano di Lombardia all'indomani del 20.02.2020: una postfazione
Authors: Alì Alessandro
Published: February 2021

L'esplosione della emergenza sanitaria dovuta all'epidemia da Covid-19 ha reso necessaria questa postfazione, proprio quando il racconto su Romano di Lombardia si accingeva a concludersi. Essa non aspira a fare bilanci né a tracciare i contorni di probabili (o improbabili) scenari evolutivi delle città all'indomani della pandemia. Vuole essere invece una riflessione (nella forma di appunti di lavoro ancora dall'interno di una condizione di emergenza sanitaria) sulla tenuta delle idee che hanno alimentato i piani e i progetti prodotti in una condizione di ‘normalità' per il territorio di Romano di Lombardia e, eventualmente, sulla loro ri-messa a fuoco alla luce del fenomeno pandemico.
L'adattamento locale al cambiamento climatico in aree alpine
Authors: Pede Elena , Staricco Luca
Published: February 2021

Le Alpi sono tra le zone più vulnerabili ai cambiamenti climatici in Europa; tuttavia il dibattito sulle strategie e le azioni di adattamento continua a concentrarsi prevalentemente sulle aree urbane e costiere maggiormente popolate. L'articolo presenta i risultati di un'indagine sulle pratiche di adattamento locale ai cambiamenti climatici messe in campo in un'area alpina, costituita dai 45 comuni della Zona omogenea del Pinerolese (Torino). L'indagine fa emergere alcune barriere che possono ostacolare l'adattamento al cambiamento climatico nei contesti montani, o comportare una sua declinazione in termini di pratiche poco sistematiche e ambiziose: una percezione del cambiamento in termini quasi esclusivi di intensificazione degli eventi estremi, l'iperframmentazione comunale, la mancanza di un'efficace governance orizzontale e verticale, la carenza di risorse finanziarie e conoscitive.
Le tecnologie appropriate nell'architettura d'emergenza
Authors: Trabattoni Luca , Berizzi Carlo , Battistella Alessio , Luisi Sonia
Published: February 2021

Negli ultimi decenni molti studi di architettura che operano in contesti di crisi umanitaria secondo l'approccio delle ‘tecnologie appropriate' stanno provando a sviluppare soluzioni alternative al progetto d'emergenza: partendo da una attenta riflessione su tecnologia e materiali, non solo ricercano soluzioni efficienti e sostenibili ma anche un'estetica e un linguaggio capaci di trarre linfa vitale dalla specificità dei luoghi. Attraverso l'analisi dell'approccio progettuale di ARCò - architettura & cooperazione, studio di Milano che opera da più di dieci anni in contesti di guerra e povertà, si intende riflettere sulle tematiche specifiche dell'architettura d'emergenza: la sostenibilità, la ricerca formale, il linguaggio e la comunicazione sono i campi entro cui si ricercano risposte adeguate, sia tecnologiche sia progettuali.
La Commissione d'Ornato a Milano, tra ortodossia classicista e cultura prospettica
Authors: D’Amia Giovanna
Published: February 2021

L'articolo prende in esame un aspetto poco indagato dell'attività della Commissione d'Ornato di Milano nella prima metà dell'Ottocento, interrogandosi sugli effetti della presenza di esponenti della cultura prospettica, come Paolo Landriani e Francesco Durelli, in un organo destinato a sovrintendere l'edilizia cittadina. Attraverso una serie di indizi tratti dalle fonti d'archivio emerge infatti la loro disponibilità ad allargare i riferimenti espressivi dalle norme vitruviane alle più libere proporzioni del linguaggio bramantesco e la loro sensibilità per la dimensione complessa dello spazio urbano. Attitudini che svolgono un'azione erosiva nei confronti dei modelli culturali su cui la commissione era chiamata a vigilare, traghettando la sensibilità della cultura architettonica milanese dal rigido classicismo di inizio secolo al più variegato panorama degli anni preunitari.
Social Media, Consumer Motivation, And Consumer Purchase Decision For Fashion Consumers In Semarang District
Authors: Sudirjo Frans
Published: February 2021

Abstract: This study aims to analyze the influence of social media on purchasing decisions through consumer motivation in fast fashion consumers in Semarang Regency. This study uses quantitative methods as many as 100 respondents were determined using a census. Data were collected using a questionnaire and processed using partial least squares. The results showed that social media had a positive and significant effect on purchasing decisions, consumer motivation had a positive and significant effect on purchasing decisions and social media had a positive and significant effect on purchasing decisions.
Changes in Commute Mode Attributed to COVID-19 Risk in Canadian National Survey Data
Authors: Harris M. Anne , Branion-Calles Michael
Published: February 2021

Transportation shifts in Canada precipitated by COVID-19 may persist into recovery. We examined commuters in a national survey (Canadian Perspectives Survey Series 3) and commute changes attributed to COVID-19 risk. We modeled associations of changing commute with pre-COVID-19 mode, adjusting for coarse socio-demographic covariates. We found that all out-of-home commute modes declined during COVID-19, with increases in telework. Commuting by public transit was most strongly associated with change in commute mode to avoid COVID-19 risk. Among pre-COVID-19 transit commuters, 18.2% continue to rely on transit, and personal motor vehicle use is more common (13.0%) than walking (3.4%) or cycling (2.9%).
BRAND LOVE AMONG FEMALE CONSUMERS FOR FASHION CLOTHING
Authors: Rajput Amer , Batool Saba , Ahmad Khan Faheem
Published: February 2021

The purpose of this study is to investigate the association of brand anthropomorphism with anticipated separation distress through mediation of brand love among female consumers for fashion clothing brands. The conceptual research framework was empirically tested and data were collected through the questionnaire survey of 302 female consumers of fashion clothing brands in Pakistan. The structural equation modelling with partial least squares (SEM-PLS) is used to analyse the conceptual research framework. An explicit description is presented about the positive association of brand anthropomorphism with the anticipated separation distress through the mediation of brand love for ‘fashion clothing among female ’. This study has empirically proven the positive association of brand anthropomorphism with the anticipated separation distress of brand love among female consumers for fashion clothing. Additionally, this study enhances the knowledge of brand love in the context of female consumers and managers of clothing brands.
THE EFFECT OF POLITICAL CONNECTIONS ON FORWARD- LOOKING INFORMATION DISCLOSURE FROM THE PERSPECTIVE OF THE STAKEHOLDER SALIENCE THEORY
Authors: Rusli Mas Nordiana , Mohd. Saleh Norman , Hassan Mohamat Sabri , Bangaan Abdullah Mohd Hafizuddin Syah
Published: February 2021

This study examines the effect of political connections (PCONS) on firms’ disclosure of forward-looking information choices in the context of developing countries. Using multivariate regression of panel data comprising 360 firmyear observations of non-financial firms listed on Bursa Malaysia between years 2014 and 2017, PCONS are found to be positively associated with disclosure of forward-looking information. However, such relationship only exists for non-financial forward-looking information. Using the stakeholder salience theory to further contribute to the body of knowledge, the strength of the connections suggests that a high composition of politically-connected directors on the board promotes greater information about the future in firms’ disclosure. The common connection through ownership of firms in emerging countries suggests the effective role of institutional shareholders in improving forecasting activities through high disclosure of forward-looking information. The study suggests a better appreciation of the hierarchical role of politically-connected directors on the board of types of forward-looking information presented to the stakeholders.
Kelestarian Pembangunan Profesionalisme Guru dalam Pembelajaran Sepanjang Hayat (Sustainability of Teacher Professional Development in Lifelong Learning)
Authors: Saad Norazlinda , Sankaran Surendran
Published: February 2021

Kajian ini bertujuan untuk mengenal pasti hubungan antara kesesuaian dan kerelevanan modul dengan persepsi guru terhadap Modul T3P dalam pembangunan profesionalisme guru. Kajian ini berbentuk deskriptif dengan menggunakan kaedah tinjauan. Populasi kajian terdiri daripada guru-guru Sekolah Menengah Kebangsaan (SMK) di Negeri Perlis, Kedah dan Pulau Pinang. Seramai 60 orang guru dipilih dengan menggunakan persampelan bertujuan. Modul T3P dan soal selidik digunakan sebagai instrumen kajian dan item-item untuk soal selidik diadaptasikan dari kajian-kajian lepas dan tinjauan literatur. Dalam kajian rintis beberapa aspek penyesuaian item telah dijalankan sehingga terhasil nilai Cronbach Alpha yang tinggi (0.90). Data yang dikumpul dianalisis dengan menggunakan statistik deskriptif dan korelasi pearson. Dapatan kajian juga menunjukkan bahawa variabel kesesuaian dan kerelevanan modul T3P mempunyai hubungan yang signifikan dan tinggi dengan persepsi guru terhadap Modul T3P. Dapatan kajian memberi implikasi bahawa pembangunan profesionalisme keguruan yang sesuai dan relevan amat diperlukan untuk menambahbaik kemahiran PdPC bagi menjayakan transformasi pendidikan. Abstract The purpose of this study is to identify the relationship between the suitability and relevance of the module with teachers’ perceptions on the T3P Module in the development of teacher professionalism. This study is using the descriptive survey method. The population of the study consists of Secondary School (SMK) teachers in the states of Perlis, Kedah and Penang. A total of 60 teachers was selected using purposeful sampling. T3P modules and questionnaires were used as research instruments and items for questionnaires were adapted from previous studies and literature reviews. In the pilot study several aspects of item adjustment were carried out resulting in a high Cronbach Alpha value (0.90). The collected data were analyzed using descriptive statistics and Pearson correlations. The findings show that the suitability and relevance variables have a significant and high relationship with teachers’ perceptions with the T3P Module. The findings of the study have implications that the development of suitable and relevant teaching professionalism is essential to improve teaching and facilitating skills for successful educational transformation. Keywords: Teacher professionalism development, lifelong learning, suitability and relevance.
Sifat Spiritual Ibu Bapa dan Estim Kendiri dalam Kalangan Pelajar Universiti (The Spiritual Characteristics of Parents and Self-Esteem in Universities Students)
Authors: Adiha Tewiran Syaliza
Published: February 2021

Sifat spiritual ibu bapa dalam mendidik anak-anak memberi impak yang sangatbesar bukan sahaja kepada hubungan kekeluargaan malah kepada personaliti anak itu sendiri apabila dewasa kelak. Kajian ini bertujuan mengenal pasti hubungan antara sifat spiritual ibu bapa dengan estim kendiri pelajar Fakulti Pengajian Pendidikan, UPM. Responden terdiri daripada 205 orang pelajar dipilih mengikut kaedah persampelan kluster. Instrumen yang digunakan iaitu soal selidik Parental Spiritual Characteristics Scales (PSCS) dan RosenbergSelf-Esteem Scale (RSES). Ujian statistik yang digunakan ialah kaedah analisis diskriptif dan analisis Pearson Correlation. Hasil kajian menunjukkan terdapat hubungan sifat spiritual ibu bapa dengan estim kendiri pelajar Fakulti Pengajian Pendidikan, UPM. Kajian ini turut memberikan manfaat kepada pihak universiti, ibu bapa dan kaunselor dalam memahami aspek-aspek sifat spiritual ibu bapa dan estim kendiri pelajar. Abstract The spiritual nature of parents in educating children has a tremendous impact not only on family relationships but also on the child’s own personality when they become adults. The purpose of this study is to identify the spiritual characteristics of parents who are often practiced with the students’ selfesteem of the Faculty of Educational Studies, UPM. Respondents were 205 students, selected according to cluster sampling method. The instruments used were Parental Spiritual Characteristics Scales (PSCS) and Rosenberg Self-Esteem Scale (RSES). The statistical test used is descriptive analysis and Pearson Correlation. The results showed that there was a relationship between the parents’ spiritual character and the self-esteem of the Faculty of Educational Studies, UPM. This study also benefits the university, parents and counselors in understanding aspects of parent’s spiritual traits and student self- esteem. Keywords: Spiritual characteristics, self- esteem, parent-child correlation.
FOREIGN DIRECT INVESTMENT AND THE PERFORMANCE OF INDONESIAN MARKETPLACE E-COMMERCE CORPORATION: AN APPLICATION OF NETWORK, OWNERSHIP, LOCATION AND INTERNALISATION FRAMEWORK
Authors: Kaukab ‪M. Elfan , Aryanto Vincent Didiek Wiet
Published: February 2021

Data on real-time marketing performance from micro, small and medium enterprises (MSMEs) selling their products in marketplace e-commerce corporations (MECCs) is a big challenge for researchers studying the performance of MECCs capital structure. This article explores the use of Google Trends to determine the impact of Foreign Direct Investment (FDI) on MECCs’ performance. The findings of the trend analysis are explained using the N-OLI framework. It is found that there was a sharp trend decrease in MECCs with partial FDI (Tokopedia and Bukalapak) and full domestic investment (Blibli).On the other hand, there was a sharp increase in MECCs full FDI (Shopee). Other MECCs with full FDI, namely Lazada, has experienced a decrease but it is not as consistent as that of partial FDI. An increase trend in Shopee has negative correlation with a decline trend in Bukalapak. However, after being grouped, partial FDI has a significantly higher mean score compared to full FDI, and MECCs without FDI has the lowest mean score. This finding shows that in the case of Indonesia, FDI plays a role in encouraging the success of MSMEs, especially in MECCs, which have a combination of FDI and domestic investment.
ACTORS IN INDUSTRIAL RELATIONS: GROWTHS AND DWARFISM OF INDUSTRIAL RELATIONS SYSTEM IN NIGERIA
Authors: ‪Mustapha Olanrewaju Aliyu , Ismaila Kadiri Bolarinwa
Published: February 2021

The study focused on the actors in industrial relations and their contributions towards the growth and dwarfism of Nigeria’s industrial relations system. It identified some problems which have been brought by other actors in industrial relations - the employees. In pursuit of the previously mentioned objectives, a survey research was employed. The population used for the study was 160 staff of Micheal Imoudu Institute for Labour Studies, Ilorin, Nigeria. A sample size of 114 was determined using Taro Yamani’s formula (1964). The study made use of both primary and secondary data and questionnaires were administered to 114 staff but only 99 were collected, analysed and interpreted. The multiple regression analysis was used to test the hypotheses at 0.05 significant level using SPSS v.20. It was found that governments at all levels have significant impacts on the growth and dwarfism of the industrial relations system of Nigeria. The study concluded that actors in industrial relations in Nigeria affect the growths and dwarfisms of Nigeria’s industrial relations system and it is recommended that further research be extended to other industries such as construction, agriculture and telecommunication. The study can also be used as guidelines for human resource aficionados and industrial relations experts.
INCLUSÃO ESCOLAR: ASPECTOS LEGAIS E AÇÃO DOCENTE
Authors: Nepomoceno Taiane Aparecida Ribeiro , Costa Analides Flávia Caruso , Picelli Lucyelena Amaral
Published: February 2021

A educação inclusiva fundamenta-se numa concepção de escola como espaço uno, de humanização que, sem dúvidas, enfrenta diversos impasses no contexto atual. Ela representa mais que um conceito concatenado ao acesso à educação de qualidade para todos no ensino regular, mas sim um modo de pensar e desenvolver a ação docente. Objetiva-se nesse trabalho discutir o processo inclusivo escolar e sua relação com as práticas pedagógicas e a docência na educação básica. Este estudo possui cunho exploratório e o encaminhamento metodológico aconteceu através de revisão bibliográfica, tendo por base autores que fundamentam a temática. As políticas públicas asseguram a matrícula ao ensino regular, contudo, não há, na prática a garantia de uma permanência de qualidade aos seus pares. Nesse sentido, práticas pedagógicas adequadas podem proporcionar condições ideais para a aprendizagem e desenvolvimento dos alunos com e sem necessidades educacionais especiais. A ação docente deve ser transformadora e romper com as práticas fragmentadas, que reduzem as singularidades dos educandos.
Cetuximab plus radiotherapy for the treatment of locally advanced squamous cell carcinoma of the head and neck
Authors: Griffin S , Walker S , Sculpher M , White S , Erhorn S , Brent S , Dyker A , Ferrie L , Gilfillan C , Horsley W , Macfarlane K , Thomas S
Published: February 2021

This paper presents a summary of the evidence review group (ERG) report into the clinical and cost-effectiveness of cetuximab plus radiotherapy for the treatment of locally advanced squamous cell carcinoma of the head and neck (LA SCCHN) considered inappropriate for chemoradiotherapy but appropriate for radiotherapy, based upon the evidence submission from Merck Pharmaceuticals to the National Institute for Health and Clinical Excellence (NICE) as part of the single technology appraisal (STA) process. The manufacturer’s submission was generally of good quality and was an accurate representation of the original reference data. One good-quality randomised controlled trial comparing radiotherapy plus cetuximab with radiotherapy alone in patients with stage III or IV non-metastatic LA SCCHN was included, demonstrating that the duration of locoregional control was significantly longer with radiotherapy plus cetuximab than with radiotherapy alone; also, overall and progression-free survival were significantly longer and the overall response rate was significantly better with the combination therapy. Cetuximab did not exacerbate the common toxic effects associated with radiotherapy of the head and neck. No supporting evidence for these findings are available. The patient population in the trial included a high proportion of patients who would be expected to be suitable for chemoradiotherapy and therefore does not match the population described in the submission’s decision problem. Also, the radiotherapy regimens used in the trial are not typical of current UK practice. The ERG considered the manufacturer’s economic evaluation to comprise the only relevant evidence to consider for the purposes of this STA. The economic model was considered appropriate for the decision problem. The results suggested that cetuximab plus radiotherapy was cost-effective compared with radiotherapy alone under a broad range of different assumptions on the basis of a cost-effectiveness threshold of £20,000. In the base case the incremental cost-effectiveness ratio of cetuximab plus radiotherapy compared with radiotherapy alone in the treatment of patients with LA SCCHN was £6390 per additional QALY. Simple sensitivity analyses to examine the robustness of the results were undertaken, suggesting that areas of uncertainty that emerged in the modelling are unlikely to have a material effect on the conclusions. The guidance issued by NICE in May 2007 as a result of the STA states that cetuximab in combination with radiotherapy is not recommended for patients with LA SCCHN.