bluuebunny/crossref_metadata_2025 huggingface dataset:
ПОКАЗАТЕЛИ КАЧЕСТВЕННОГО И КОЛИЧЕСТВЕННОГО АНАЛИЗА АНТИТЕЛ К ЦИТОМЕГАЛОВИРУСУ
Authors: Касенов Д.К. , Сулейманова Ш.С. , Жусупова А.Т.
Published: October 2024

В данной работе представлены результаты количественного и качественного анализа по выявлению антител иммуноглобулина G и M на цитомегаловирус с помощь иммуноферментного анализа. Практически в большинстве стран, иммуноферментный анализ является неотъемлемой частью диагностики, с внедрением передовых технологий и методов анализа стало возможно и определение количества антител на вирусы в организме способствует назначению своевременного лечения, а также проведению профилактических мероприятий. Работа проведена совместно с клиническими врачами, лаборантами одной из клинических лабораторий г. Бишкек. При проведении ручных и автоматических лабораторных исследований были использованы передовые технологии и инструментарии. Авторами показана значимость возрастной категории и других факторов для внедрения данного вида анализа как скрининговый метод медицинского осмотра.

This paper presents the results of quantitative and qualitative analysis for the detection of immunoglobulin G and M antibodies to cytomegalovirus using enzyme immunoassay. In almost most countries, enzyme immunoassay is an integral part of diagnosis, and determining the amount, of antibodies to viruses in the body contributes to the appointment of timely treatment, as well as preventive measures. The work was carried out jointly with clinical doctors, laboratory assistants of one of the clinical laboratories in Bishkek. Advanced technologies and tools were used during manual and automatic laboratory tests. The authors show the importance of the age category and other factors for the introduction of this type of analysis as a screening method of medical examination.

Бул эмгекте ферменттик иммунологиялык анализ аркылуу Цитомегаловируска каршы иммуноглобулин Антителолорун аныктоо үчүн сандык жана сапаттык анализдин жыйынтыктары келтирилген. Дээрлик көпчүлүк өлкөлөрдө иммундук анализ диагностиканын ажырагыс бөлүгү болуп саналат жана организмдеги вирустарга антителолордун санын аныктоо өз убагында дарылоону, ошондой эле алдын алуу чараларын белгилөөгө өбөлгө түзөт. Иш Бишкектеги клиникалык лабораториялардын биринде дарыгер-клиницисттер, лаборанттар менен биргеликте жүргүзүлдү. Кол менен жана автоматтык лабораториялык сыноолорду жүргүзүүдө алдыңкы технологиялар жана шаймандар колдонулган. Авторлор медициналык текшерүүнүн скрининг ыкмасы катары анализдин бул түрүн киргизүү үчүн курактык категориянын жана башка факторлордун маанилүүлүгүн көрсөтүшөт.
АЗЫРКЫ БИЛИМ БЕРҮҮ СИСТЕМАСЫНДА СТУДЕНТТЕРГЕ ТЕАТРАЛДЫК ЖАНА КӨРКӨМ-ЭСТЕТИКАЛЫК ТАРБИЯ БЕРҮҮНҮН АКТУАЛДУУЛУГУ
Authors: Тыналиева Г.Т.
Published: October 2024

Заманбап адамдын практикалык ишмердүүлүк процессинде илимий билимдердин комплекси гана эмес, ошондой эле эстетикалык билим берүүнүн жана тарбиялоонун ролу жогорулаган жогорку жалпы маданий жана адеп-ахлак потенциалы талап кылынат, бул негизинен эстетикалык ой жүгүртүүлөрдү калыптандыруу маселелерин чечет, табити жаш адамдын эмоционалдык дүйнөсүн өнүктүрүү. “Театр жасоонун” эң жаңы ыкмалары биринчи кезекте жаңы көрүүчүнүн кабыл алуусунун өзгөрүшүнө, анын чыгармачылык потенциалын активдешине, биздин дүйнөнү кабылдообуздун санариптештирилишине байланыштуу жана театрдын көрүүчүлөргө жаңы сезим берүү аракети болуп саналат, таасир этүүнүн интеллектуалдык ыкмаларын сезүү ыкмаларына которуу. Билим берүү процессин геймификациялоо практикасы студенттерди окууга тартуу менен чыгармачылык ой жүгүртүүнү,”жумшак көндүмдөрдү”же креативдик ой жүгүртүүгө жардам берет.

От современного человека требуется не только комплекс научных знаний, необходимый в процессе практической деятельности, но также высокий общекультурный и нравственный потенциал, где возрастает роль эстетических суждений, вкусов, развитие эмоционального мира молодого человека, служит укреплению сознания, убежденности, становлению всего его духовного облика. Новейшие способы» делать театр» прежде всего, обусловлены меняющимся восприятием нового зрителя, активизацией его творческого потенциала, дигитализацией нашего восприятие мира и является попыткой театра дать аудитории новый сенсорный опыт и перевести интеллектуальные методы воздействия в чувственные. Практика геймификации учебного процесса вовлекает студентов в обучении помогает развивать креативные мышление.

From a modern person, not only a complex of scientific knowledge is required in the process of practical activity, but also a high general cultural and moral potential, where the role of aesthetic judgments, tastes, the development of the emotional world of a young person increases, serves to strengthen consciousness, conviction, the formation of his entire spiritual appearance. The newest ways to "do the theater" are primarily due to the changing perception of the new viewer, the activation of his creative potential, the digitalization of our perception of the world and is an attempt by the theater to give the audience a new sensory experience and translate intellectual methods of influence into sensual ones. The practice of gamification of the educational process involves students in learning and helps develop creative thinking.
ПЕРЕСЕЧЕНИЕ ТЕХНОЛОГИЙ И МОДЫ: КАК 3D-ПЕЧАТЬ ВНЕДРЯЕТ ИННОВАЦИИ В ИНДУСТРИЮ
Authors: Нургазы к.М. , Лобанов Н.А.
Published: October 2024

Данная статья посвящена анализу применения 3D-печати в текстильной промышленности с целью производства одежды. В статье описываются особенности технологий 3D-печати и анализируются проблемы, такие как доступность материалов и ограниченный размер печатных платформ. Авторы приводят аргументы в пользу использования технологии селективного лазерного спекания, так как она обладает гибкостью и эластичностью материалов, что является важным для производства элементов одежды. Кроме того, статья рассматривает перспективность создания гибридных изделий, в которых могут сочетаться 3D-печатные элементы и традиционный текстиль. Такой подход может привести к новым возможностям для дизайна и производства одежды. Тем не менее, авторы признают, что все еще существуют ограничения на пути использования 3D-печати в текстильной промышленности, и считают, что необходимо продолжать исследования и разработки в этой области.

Бул макала кийим тигүү максатында текстиль өнөр жайында 3Д басманын колдонулушун талдоого арналган. Макалада 3Д басып чыгаруу технологиясынын өзгөчөлүктөрү сүрөттөлөт жана материалдардын жеткиликтүүлүгү жана басма платформаларынын чектелген көлөмү сыяктуу маселелер талданат. Автор тандалма Лазердик агломерация технологиясын колдонууну жактайт, анткени ал кийим элементтерин өндүрүү үчүн маанилүү болгон материалдардын ийкемдүүлүгүнө жана ийкемдүүлүгүнө ээ. Мындан тышкары, макалада 3Д басма элементтерин жана салттуу текстилди айкалыштыра турган гибриддик буюмдарды түзүүнүн келечеги каралат. Бул ыкма кийим дизайны жана өндүрүш үчүн жаңы мүмкүнчүлүктөргө алып келиши мүмкүн. Бирок, авторлор текстиль өнөр жайында 3Д басып чыгарууну колдонуу жолунда дагы эле чектөөлөр бар экенин моюнга алышат жана бул жаатта изилдөө жана иштеп чыгууну улантуу керек деп эсептешет.

This article is devoted to the analysis of the application of 3D printing in the textile industry for the production of clothing. The article describes the features of 3D printing technologies and analyzes problems such as the availability of materials and the limited size of printing platforms. The authors argue in favor of using selective laser sintering technology, since it has the flexibility and elasticity of materials, which is important for the production of clothing items. In addition, the article considers the prospects of creating hybrid products in which 3D-printed elements and traditional textiles can be combined. This approach can lead to new opportunities for the design and production of clothing. Nevertheless, the authors acknowledge that there are still limitations on the use of 3D printing in the textile industry, and believe that it is necessary to continue research and development in this area.
ПОНЯТИЕ ДИСКУРСА И ИНТЕРНЕТ-ДИСКУРСА В СОВРЕМЕННОЙ ЛИНГВИСТИКЕ
Authors: Шерматова А.М. , Алимжан к.Ж.
Published: October 2024

Статья рассматривает понятие интернет-дискурса в современной лингвистике. Исследуются осо6енности электронной коммуникации. Дается определение «Интернет-дискурса» и различные подходы к его изучению. Авторы описывают особенности интернет-коммуникации, а также анализируют основные характеристики и элементы интернет-дискурса. В статье также рассматриваются возможности и ограничения применения методов лингвистического анализа в исследовании интернет-дискурса. Авторы обращают внимание на важность анализа интернет-дискурса для понимания современной коммуникативной практики и для развития современной лингвистики. В итоге статьи делается вывод о том, что интернет-дискурс представляет собой важное направление в лингвистических исследованиях.

The article considers the concept of Internet discourse in modern linguistics. The features of electronic communication are being investigated. The definition of "Internet disk" and various approaches to its study are given. The authors describe the features of Internet communication, as well as analyze the main characteristics and elements of Internet discourse. The article also discusses the possibilities and limitations of using the methods of linguistic analysis in the study of Internet discourse. The authors draw attention to the importance of Internet discourse analysis for understanding modern communicative practice and for the development of modern linguistics. As a result of the article, it is concluded that the Internet discourse is an important direction in linguistic research.

Макалада заманбап лингвистикадагы интернет дискурс түшүнүгү каралат. Электрондук байланыштын өзгөчөлүктөрү иликтенип жатат. Макалада «Интернет-дискурстун» аныктамасы жана аны изилдөөнүн ар кандай жолдору берилген. Авторлор интернет байланышынын өзгөчөлүктөрүн сү-рөттөп, ошондой эле Интернет-дискурстун негизги мүнөздөмөлөрүн жана элементтерин талдашат. Макалада ошондой эле Интернет дискурсун изилдөөдө лингвистикалык анализдин ыкмаларын колдонуунун мүмкүнчүлүктөрү жана чектөөлөрү талкууланат. Авторлор заманбап коммуникативдик практиканы түшүнүү жана заманбап лингвистиканы өнүктүрүү үчүн Интернет-дискурстук анализдин маанилүүлүгүнө көңүл бурушат. Макаланын жыйынтыгында интернет дискурс лингвистикалык изилдөөлөрдүн маанилүү багыты болуп саналат деген тыянак чыгарылат.
The role of civic education in shaping the character of students at al hikam islamic boarding school, bangkalan
Authors: Mas'ud Mochammad , Eka Indriani Dian , Sahid M.
Published: October 2024

Civic Education plays a crucial role in shaping the character of students, providing a moral foundation for building a tolerant and just society. This research focuses on tolerance at Pondok Pesantren Al Hikam Bangkalan, exploring the relationship between civic education and student character. Using a descriptive qualitative approach, this study involved observations and interviews with 10 students. The results show that 80% of students regularly participate in learning activities, all students display respectful behavior towards teachers, and 90% maintain environmental cleanliness. Furthermore, all students refrain from discrimination and respect differences, creating an inclusive and safe social environment. Interviews revealed a strong understanding of Pancasila values and the importance of tolerance. Civic education at Pondok Pesantren Al Hikam has proven effective in shaping students' character to appreciate diversity and the values of tolerance. This research provides valuable insights for the development of policies and practices in civic education at Islamic boarding schools.
REASONS FOR THE FALL OF THE LIBER INTERNATIONAL ORDER FROM THE PERSPECTIVE OF WORLD POLITICS
Authors:   AL-FARABI KAZAKH NATIONAL UNIVERSITY, Li Xue
Published: October 2024

In recent years, the gradual fall of the liberal international order, once heralded as the “end of history”, has become an indisputable fact. The world politics aims to explain changes in the nature and foundational systems of international relations, as well as global and domestic politics. Examining the decline of the liberal international order through the paradigm of world politics can comprehensively elucidate the factors affecting the development of both international relations and domestic politics simultaneously, thereby theoretically unifying the two fields. This paper examines the decline of the liberal international order from the perspective of world politics and posits that its decline is attributable to both internal and external reasons: Internally, the economic foundations, rule enforcement, and value propositions of the liberal international order harbor “the seeds of its own destruction”; externally, the influence of developing countries on the traditional value chain, the revisionist foreign policy of major powers, and the politics of striving for recognition have accelerated the decline of the liberal international order. Ultimately, this paper concludes that the decline of the liberal international order is inevitable and, with the waning of the unipolar pattern, the world order is destined to evolve towards a more equitable and fair direction.
THEORETICAL AND METHODOLOGICAL APPROACHES TO THE STUDY OF MIGRATION FROM CHINA TO KAZAKHSTAN
Authors:   AL-FARABI KAZAKH NATIONAL UNIVERSITY, Altynbek Aygerim , Karimova Zulfiya
Published: October 2024

The migration process from China to Kazakhstan is complex, poorly understood, and requires a variety of theoretical and methodological approaches to fully understand its dynamics. For this purpose, this paper applies theories of international migration to gain a better understanding of the movement of migrants between the two countries. The study focuses on macro-level migration theories to identify the political and economic implications of migration in the context of Kazakhstan-China relations. The study highlights the need for integrated methods, including both qualitative and quantitative approaches such as surveys, interviews, and case studies, to capture the multifaceted nature of migration. It also highlights the need for improved data collection methods and suggests that a combination of administrative data, expert assessments, and sample surveys can provide a more accurate understanding of illegal migration. The paper pays particular attention to irregular migration, given the high numbers of migrants from PRC to Kazakhstan, primarily for economic reasons. Thus, the paper attempts to map out the dynamics of Chinese-Kazakh migration by highlighting its history, development, sources, and factors, using findings from Western and domestic scholars.
Impact of climate change on international trade and economy: challenges and opportunities
Authors:   AL-FARABI KAZAKH NATIONAL UNIVERSITY, Shonay Askar , Kurmangali Aimen , Morgunova Oksana
Published: October 2024

The presented research article provides an in-depth analysis of the multidimensional impact of climate change on international trade and the global economic system. The study focuses on a comprehensive examination of the direct and indirect effects of climatic factors, such as extreme weather events, which lead to significant disruptions in supply chains, production processes and infrastructure. The paper emphasises the critical link between environmental change and international economic activity, justifying how climate change can cause fluctuations in global markets through agricultural losses and infrastructure damage. The article proposes a methodological approach aimed at generating strategies for adapting to and minimising the negative impacts of climate change that are suitable for implementation at national and international levels. The strategies developed by the authors include proposals to improve environmental sustainability and economic efficiency, contributing to sustainable development and stability in a changing climate. This approach involves the active inclusion of international co-operative initiatives as well as the development of new technologies and innovations to adapt international trade to new environmental realities. This research article will be useful for academic researchers, policy analysts and practitioners in the field of international trade and economics, providing a theoretical and practical framework for developing climate change adaptation strategies.
Development of Teaching Materials Based on Pjbl-Abmh (Preserved Bioplastic Materials Set) To Improve Students' Creative Thinking Skills
Authors: Auni Anggita , Farida Siti , Arfiansyah Noval Ilham , Sari Yurizka Melia
Published: October 2024

This research describes the process and results of developing PJBL-ABMH-based learning tools to improve students' creative thinking abilities on set material. This research uses the Plomp development model to develop learning tools through teaching modules and project worksheets, setting material with the PJBL-ABMH project learning design. The trial was conducted on 6 grade 7 students at a junior high school in Surabaya, East Java. Data collection and analysis techniques are carried out using validation sheets to determine the validity of the learning tools tested on the validator. Pre-test and posttest sheets measure effectiveness regarding students' creative thinking abilities on set material. Apart from that, student response sheets are also used to determine the practicality of the learning tools that have been developed. Data analysis was carried out using the constant comparative method technique. The results of the data analysis showed that the learning tools obtained a validity criterion of 75.5%, and each was classified as valid. The n-gain was obtained at 0.736 for the effectiveness criteria, and each obtained high effectiveness criteria. The learning tools were efficient to implement, with an average student response of 90% for the project learning design. Thus, PJBL-ABMH-based learning tools are declared valid, effective, and practical.
Classificação de rios modificados e controlados por obras hidráulicas na Bacia do rio Guandu (RJ)
Authors: Ornelas Teixeira Jenner , Dos Santos Marçal Mônica , Osdayan Cândido de Castro Adão
Published: October 2024

O funcionamento de um rio compreende a ação de diversos processos biofísicos e socioculturais que atuam de forma conjunta e em múltiplas escalas. As metodologias de classificação dos rios são importantes ferramentas que auxiliam na compreensão dessa complexidade. Com a imposição de diversas obras hidráulicas nos cursos fluviais, os rios têm sua trajetória de evolução e capacidade natural de funcionamento comprometidas, como é o caso da Bacia do rio Guandu, principalmente em sua área de planície. Com base na metodologia de classificação de rios denominada de Estilos Fluviais, o objetivo do trabalho consiste na classificação e elaboração de tipologias fluviais para rios antropicamente modificados da Bacia do rio Guandu. Os Estilos Fluviais foram classificados a partir da identificação das obras hidráulicas, compartimentos geomorfológicos, forma em planta do canal, geometria do canal, composição do leito e unidades geomorfológicas. Identificou-se quatro Estilos Fluviais antropicamente controlados, os quais possuem obras hidráulicas responsáveis pelo controle primário dos canais, como barragens, reservatórios e retificações, impondo modificações na morfologia e no comportamento dos rios. Estes resultados favorecem o entendimento do funcionamento e das mudanças ocorridas na bacia e auxiliam na implantação de um sistema de monitoramento hidrossedimentar mais eficaz.
PRINCIPAIS MODELOS UTILIZADOS PARA AVALIAR VULNERABILIDADE DOS AQUÍFEROS CÁRSTICOS BRASILEIROS: UMA REVISÃO
Authors: Oliveira Olavo Amancio
Published: October 2024

A escolha do modelo apropriado para avaliar a vulnerabilidade dos aquíferos cársticos no Brasil ainda não alcançou patamares conclusivos, principalmente considerando o tamanho do país. Assim, esta pesquisa procurou identificar o modelo mais utilizado para avaliar a vulnerabilidade dos aquíferos cársticos brasileiros. A pesquisa bibliográfica foi elaborada a partir de uma coletânea de artigos publicados em periódicos nacionais e internacionais indexados na plataforma Web of Science, além de Dissertações de Mestrados e Teses de Doutoramento, o que permitiu identificar o estado da arte da pesquisa. Dessa forma, identificamos quais são os modelos mais utilizados, os métodos de aplicações, os aspectos físicos das áreas e a escala de aplicação. Os modelos encontrados foram: COP, DRASTIC, GOD, EPIK, PI, SINTACS, KDI e MAIA. Apenas 04 modelos (COP, EPIK, PI e KDI) apresentam metodologia específica para avaliar a vulnerabilidade de aquíferos cársticos. Os outros, embora apontados nesta pesquisa para avaliar a vulnerabilidade das águas subterrâneas de aquíferos cársticos, quando propostos, não foram indicados para serem aplicados em aquíferos cársticos. Dos quatro modelos indicados para o carste, os mais utilizados foram o COP e o EPIK. O modelo EPIK, além de trabalhar com uma quantidade maior de parâmetros, é indicado para aplicação em escala local e em regiões de clima úmido. O modelo COP, que trabalha com número de parâmetros menor, é indicado para aplicação em escala regional e em regiões com clima seco. Desse modo, o modelo COP se sobressai frente aos outros e possibilita a execução de estudos sem dependência de grandes investimentos.
Oportunidades para ampliar a segurança hídrica nas bacias hidrográficas de Minas Gerais
Authors: Bastos Mayara , Cézar de Almeida Monte-Mor Roberto
Published: October 2024

O cenário de crise hídrica enfrentado por diversas regiões brasileiras nos últimos anos impõe a urgência de ações direcionadas à segurança hídrica, movimento que deve abranger, dentre outros aspectos, a universalização do saneamento. Diante das inúmeras ações necessárias para construção e manutenção da segurança hídrica, é basilar que seja realizado um diagnóstico das bacias hidrográficas por meio de indicadores com o objetivo de guiar o planejamento, a atuação e a avaliação dos resultados. Diante disso e considerando a realidade das 36 Circunscrições Hidrográficas de Minas Gerais, este estudo propõe identificar áreas críticas em termos de saneamento por meio de mapas que evidenciam a situação dos serviços de esgotamento sanitário e das perdas de água. Os dados para esta pesquisa referem-se a 2020 e foram coletados Sistema Nacional de Informações sobre Saneamento (SNIS) e no Instituto Mineiro de Gestão das Águas (IGAM). Pela metodologia adotada, observou-se que as Circunscrições Hidrográficas do Rio Paraopeba, Afluentes Mineiros dos Rios Preto e Paraibuna, Entorno da Represa de Três Marias, Rio Urucuia, Santo Antônio, Rio Caratinga e Afluentes Mineiros dos Rios Pompa e Muriaé demandam atenção dos tomadores de decisão, pois foram enquadrados no cenário de alerta em ao menos dois dos três índices calculados no estudo: coleta de esgoto sanitário, tratamento de esgoto coletado e perdas de água.
Early unrecognised SARS-CoV-2 introductions shaped the first pandemic wave, Sweden, 2020
Authors: Dyrdak Robert , Hodcroft Emma B , Broddesson Sandra , Grabbe Malin , Franklin Hildur , Gisslén Magnus , Holm Maricris E , Lindh Magnus , Nederby-Öhd Joanna , Ringlander Johan , Sundqvist Martin , Neher Richard A , Albert Jan
Published: October 2024

Background

Despite the unprecedented measures implemented globally in early 2020 to prevent the spread of SARS-CoV-2, Sweden, as many other countries, experienced a severe first wave during the COVID-19 pandemic.

Aim

We investigated the introduction and spread of SARS-CoV-2 into Sweden.

Methods

We analysed stored respiratory specimens (n = 1,979), sampled 7 February–2 April 2020, by PCR for SARS-CoV-2 and sequenced PCR-positive specimens. Sequences generated from newly detected cases and stored positive specimens February–June 2020 (n = 954) were combined with sequences (Sweden: n = 730; other countries: n = 129,913) retrieved from other sources for Nextstrain clade assignment and phylogenetic analyses.

Results

Twelve previously unrecognised SARS-CoV-2 cases were identified: the earliest was sampled on 3 March, 1 week before recognised community transmission. We showed an early influx of clades 20A and 20B from Italy (201/328, 61% of cases exposed abroad) and clades 19A and 20C from Austria (61/328, 19%). Clade 20C dominated the first wave (20C: 908/1,684, 54%; 20B: 438/1,684, 26%; 20A: 263/1,684, 16%), and 800 of 1,684 (48%) Swedish sequences formed a country-specific 20C cluster defined by a spike mutation (G24368T). At the regional level, the proportion of clade 20C sequences correlated with an earlier weighted mean date of COVID-19 deaths.

Conclusion

Community transmission in Sweden started when mitigation efforts still focused on preventing influx. This created a transmission advantage for clade 20C, likely introduced from ongoing cryptic spread in Austria. Therefore, pandemic preparedness should have a comprehensive approach, including capacity for large-scale diagnostics to allow early detection of travel-related cases and community transmission.
GEOLOGICAL AND GEOPHYSICAL MODEL OF THE CENTRAL PART OF THE YENISEI-KHATANGA REGIONAL TROUGH BASED ON THE RESULTS OF COMPREHENSIVE INTERPRETATION OF MODERN SEISMICAND GRAVITY-MAGNETIC SURVEYS
Authors:   Russian Research Geological Petroleum Institute, Ivanova Sofya , Obukhov Aleksandr , Korneyev Anton , Kalamkarov Sergey , Loshakova Inna , Sokolova Tatiana ,   Russian Research Geological Petroleum Institute,   Russian Research Geological Petroleum Institute,   Russian Research Geological Petroleum Institute,   Russian Research Geological Petroleum Institute,   Lomonosov Moscow State University
Published: October 2024

New data on potential fields are presented, compared with previous ideas about the regional structure and rift genesis of the Yenisei-Khatanga regional depression basement. Our 2D modeling based on geophysical data confirms the results of previous works regarding the identification of two types of the basement, and is consistent with the gravity-geodynamic concept of the formation of the Yenisei-Khatanga regional trough and the tectonic structures that complicate it, such as the Rassokhinsky and Balakhna megaridges. Also, as a result of our study of potential fields, the presence of a large volume of magmatic masses of ultrabasic and basic composition in the axial part of the Yenisei-Khatanga regional trough, Permian-Triassic age, was established, which confirms the rift mode of the region's development.
TÜRKİYE’DE HANEHALKI KREDİLERİNİN EKONOMİK BÜYÜMEYE ETKİSİNİN ANALİZİ
Authors: Ceylan Fatih
Published: October 2024

Küresel finans krizi sonrası krizin etkilerini azaltmak amacıyla birçok ülkede kredi kısıtlamaları uygulanmış; ancak son dönemde özellikle gelişmekte olan ülkelerde krediye erişimi kolaylaştıran gelişmeler ve politika teşvikleri ile hanehalkı kredilerinde artışlar yaşanmıştır. Bu dönemde hanehalkı kredilerinin ön plana çıkması ile ekonomik etkileri de tartışmaları beraberinde getirmiştir. Bu nedenle çalışma Türkiye’de hanehalkı kredilerinin ekonomik büyüme üzerindeki etkilerini ampirik olarak değerlendirmeyi amaçlamıştır. Ampirik analizde uzun ve kısa dönem bulgular doğrusal ve doğrusal olmayan ARDL modellerine dayanmaktadır. 2008Q3-2023Q2 dönem aralığı kullanılan çalışmada, Türkiye'de hanehalkı kredilerinin ekonomik büyüme üzerinde pozitif bir etkiye sahip olduğu; ancak hanehalkı kredilerinin azaldığı (düşük oynaklık) dönemlerde bu etkinin pozitif ve daha büyük olduğu tespit edilmiştir. Bulgular Türkiye’de hanehalkı kredi büyümesinin ekonomik büyüme üzerinde olumlu etkisinin olduğunu; ancak kredi büyümesinin kontrollü olması gerektiğini göstermektedir.
EXPLORATORY DATA ANALYSIS FOR LEAF DISEASE DETECTION
Authors: Revathy M  , Elangovan Karthikeyan
Published: October 2024

Agriculture plays a significant part in India due to their population growth and increased food demands. Hence, there is a need to enhance the yield of crop. One of these important effects on low crop yields is diseases caused by bacteria, fungi and viruses. This can be prevented and handled by means of applying plant disease detection approaches. Machine learning techniques will be employed in the process of disease identification on plants as it mostly applies information themselves and offers fabulous techniques for detection of plant diseases. Analysis of the sickness should be done appropriately and proper movements must be taken at the correct time. A correct detection of leaf disorder is crucial for plant culture as well as the rural financial system. Even though many works were executed for identifying leaf disease, due to the inadequate strategies additionally the obligations about classifying leaf disorder is difficult to be expecting This paper explores the Ada Boost with Naïve Bayes perform well as well it showing an efficient outcome. It has the greatest accuracy result of 85.75%. The Ada Boost with Naïve Bayes produces the greatest precision result of 0.86. The Ada Boost with Naïve Bayes and Stochastic Gradient Boost with Naïve Bayes produce the maximum recall of 0.86. The Ada Boost with Naïve Bayes has the greatest F-Measure result of 0.86. The Ada Boost with Naïve Bayes model has the highest MCC value of 0.65. The Ada Boost with Naïve Bayes model has the greatest kappa value of 0.66. The Ada Boost with Naïve Bayes model has an optimal results compare with other models.
A case study on exploring the motivation of English-major EFL students in online exchange programs
Authors: Yamamoto Junko
Published: October 2024

The COVID-19 pandemic has had a profound impact on the education sector worldwide, prompting a swift transition to technology-driven learning solutions. One notable response to this challenge has been the introduction of online versions of study-abroad and international exchange programs. Considering the limited existing research on how EFL university students perceive online international exchange programs, this study investigated the motivation of EFL students toward such programs initiated in response to the cancellation of in-person exchanges. The survey among 84 students from a private women's university in Kansai in August 2021 revealed that an overwhelming majority  (93%) expressed their desire to participate in online international exchange programs. This study gained further insights by employing the KH Coder text mining software (Higuchi, 2016) to analyze the free-text responses obtained from the questionnaire. The analysis of the responses unveiled their recognition of the distinct advantages offered by online exchange programs. Approximately half of the respondents indicated their willingness to engage in non-credit programs, while a similar percentage conveyed that academic credits could enhance their motivation to participate. Notably, the analysis of the free text revealed that the latter group's seemingly extrinsic motivation was largely self-determined, with their primary goal being program participation. These findings underscore the potential for online international exchanges to be well-received by students, particularly when academic credits are awarded. Additionally, correspondence analysis highlights that the desire to earn academic credits is a topic of interest across all school year levels.
Exploring the potential of AI for pragmatics instruction
Authors: Lee Bradford J. , Daniel R. Cook
Published: October 2024

Large language models (LLM) (e.g., ChatGPT) have garnered massive attention due to their potential to serve as interactive partners for a wide range of teaching and learning activities. In instructed second language acquisition, one potential use of LLMs is for pragmatics instruction. The current study sought to assess ChatGPT’s suitability for this task by analyzing its output in response to 144 DCTs (discourse completion tasks), which test a language learner’s ability to create apologies, requests, and refusals over differential levels of social and power distance, and degrees of imposition. Quantitatively, ChatGPT produced significantly shorter apologies than the other two speech acts (p < .001, R2 = .49), utilizing fewer pragmatic strategies (p < .001, R2 = .38). Closer social distance and greater imposition also resulted in longer responses, with higher imposition also eliciting ChatGPT to use more pragmatic strategies. Qualitatively, human raters scored ChatGPT’s apologies significantly lower in terms of their appropriateness, politeness, and language use, despite there being no statistical differences in ratings for requests and refusals. The main pedagogical implications are that, while ChatGPT offers an attractive option for students looking for more language exposure and interaction outside of the classroom, some degree of skepticism is still required due to its quantitative and qualitative inconsistencies.
Imbalance of immunoregulatory molecular cellular mechanisms as a cause of recurrent miscarriage
Authors: Artemyeva К. , Gusarova Т. , Bogdanova Т. , Boltovskaya М. , Nizyaeva N.
Published: October 2024

Introduction. Recurrent pregnancy loss (RPL) is an early spontaneous termination of pregnancy before 20 weeks, which is defined as two or more miscarriages. Most of the known causes associated with the pathophysiology of RPL include endocrine disorders, antiphospholipid syndrome, intrauterine infection, anatomical defects of the uterus, etc. However, in approximately 50% of cases, the cause of the pathogenesis of RPL remains unclear and may be associated with a violation of immune mechanisms, such as maternal tolerance to fetal alloantigens and controlled inflammation, which play a decisive role in successful pregnancy. Purpose of the review. To summarize current knowledge about the molecular cellular immune mechanisms that ensure the induction and maintenance of maternal-fetal tolerance and highlight the association between impaired immunoregulation and the development of RPL. Methods. The materials were the results of research on the topic over the past 23 years. Publications included in the Pubmed and eLibrary.ru databases were analyzed. Results. This review provides information about the immune regulation of pregnancy, which is carried out through the interaction of molecular mediators and effector cells of the innate and adaptive immunity. Current evidence points to a key role of the immune system in the pathophysiology of RPL. Successful pregnancy requires a finely regulated and tightly controlled balance between immune activation and tolerance to fetal antigens. Conclusion. The main events occur in the uteroplacental zone, where trophoblast cells and maternal lymphocytes come into close contact. The search for biomarkers for pregnancy complications is the focus of scientists.
Comparison of the sensitivity of restriction analysis and PCR with high-resolution melting curve analysis for the detection of the R882H mutation in the DNMT3A gene
Authors: Kulaeva E. , Muzlaeva E. , Lipilkin P. , Mashkina E.
Published: October 2024

Introduction. DNMT3A is one of the most frequently mutated genes in acute myeloid leukemia (AML), and the R882H (G>A) substitution is one of the most common mutations in this gene. Restriction analysis and high resolution melting (HRM) analysis are the most common methods used to detect this mutation, but the sensitivity of these approaches varies greatly from study to study. Purpose of the study. Determine the sensitivity of commonly used methods for assessing the R882H mutation content of a sample under controlled conditions. Methods. We compared the sensitivity of restriction analysis and HRM on presynthesized DNA samples with varying levels of mutant template in the sample and provided detailed protocols for reproducing our results by other researchers. Results. We found that the detection limit of the R882H mutation in the DNMT3A gene was 20% for restriction analysis and 40% for HRM. Conclusion. The results obtained in this work are important for identifying restriction analysis and HRM as suitable methods for use in laboratory diagnosis of the R882H mutation for patients with AML with a high mutational load.
Experimental replacement of various bladder volumes with allogeneic tissue-engineered constructions
Authors: Orlova N. , Muraviov A. , Gorelova A. , Remezova A. , Vinogradova T. , Gorbunov A. , Yudintceva N. , Nashchekina Y. , Yablonsky P.
Published: October 2024

The results of experimental replacement of the bladder wall up to subtotal using multicomponent tissue-engineered structures are presented. Purpose. Development and experimental use of a tissue-engineered structure for replacing various volumes of the bladder wall. Material and methods. The original poly-L,L-lactide matrix is reinforced with silk fibroin. Mesenchymal cells were introduced into the constructs. 6 intact animals underwent filling cystometry. The maximum cystometric capacity was 11.2±0.97 ml. In these same 6 animals, the anesthetic capacity of the bladder was measured, which was 23.83±0.71 ml. 36 animals underwent reconstruction of the bladder using a prepared tissue-engineered construct after resection of the corresponding volume of the organ. Groups of 9 animals received bladder volumes of 5, 10, 15 and 20 ml. The observation period was 3 months. Results: According to computed tomography of the abdominal and pelvic organs (native study and with intravesical administration of a radiocontrast agent), 4, 8, 12 weeks after surgery, a bladder of physiological capacity is determined in all study groups, the implanted structure is visualized as a hyperintense signal in area of the apex of the bladder. no leakage of contrast agent is detected. Filling cystometry in 2 animals that underwent replacement of 20 ml of bladder volume (subtotal replacement) after 12 weeks showed that the capacity of the formed reservoir correlates with preoperative parameters. Macroscopically, the anastomosis zone is consistent in all groups of animals, the tissue-engineered structure is determined at the implantation site, lysis of the structure is noted by 12 weeks of observation with the preservation of small residual fragments at the implantation site. Conclusion. The experimental use of the developed tissue-engineered multicomponent structure turned out to be effective for replacing defects of the bladder wall of various volumes up to subtotal reconstruction. Further study of technologies for the use of tissue-engineered allogeneic constructs can significantly improve the results of treatment of urological pathologies for which obtaining autologous material is not possible.
COMBINATION OF METHODS FOR DETERMINE THE AUTHENTICITY OF HERBS THYMUS SERPYLLUM AND THYMUS MARSHALLIANUS
Authors: Sheremetyeva A. , Fomina Yu. , Shestopalova N. , Durnova N.
Published: October 2024

Relevance. Authentication of crushed medicinal plant raw materials (RM) is an actual issue because there are species similar in morphology or there is a possibility of interspecific hybridization. The characteristics of the absorption spectra of extracts and their chromatographic profile are significant indicators of the authenticity of RS. The aim of the study was a comparative analysis by TLC and spectrophotometry of water-alcohol extracts from the herb Thymus marshallianus Willd. (TM) and Thymus serpyllum L. (TP). Material and methods. Water-alcohol extracts were obtained from 1.0 g of RS (exact suspension) in two ways (extractant – 70% ethanol, heating in a boiling water bath; extractant – 50% ethanol, 20–22 °C). Absorption spectra were recorded in the range of 200–500 nm. Eluent – ethyl acetate : formic acid anhydrous : water (70:15:15) was used for chromatography. Detection of adsorption zones was carried out after treatment with a 5% alcohol solution of AlCl3 at 365 nm. Rutin, quercetin and cinaroside were used as standard samples. Results. Microscopic analysis revealed diagnostic signs of the TM and TP leaf – trichomes of various types. The absorption spectra of water-alcohol extracts from TM and TP (obtained with 50% and 70% ethanol) have two pronounced maxima. When AlCl3 is added, a bathochromic shift of the long-wavelength absorption bands is observed. The chromatograms of these extracts revealed a yellow zone at the level of cinaroside, and differences in the number and color of the adsorption zones of TM and TP extracts. Conclusion. The absorption spectra of water-alcohol extracts have two pronounced maxima for TP of the same intensity, for TM – different. The intensity of differential absorption spectra of water-alcohol extracts of TM is higher, which indicates a higher content of flavonoids in its extracts. Cinaroside was detected in TM and TP extracts by TLC, while 11 adsorption zones are distinguishable on the chromatogram of extracts from TM herb, and 9 from TP.
PENGEMBANGAN ENSIKLOPEDIA TANAMAN ANYAMAN SUKU MELAYU KABUPATEN NATUNA
Authors: Lena Serly Marsa , Sunandar Ari , Qurbaniah Mahwar
Published: October 2024

Abstract:
Salah satu sumber belajar yang dapat digunakan adalah ensiklopedia. Ensiklopedia mampu memberikan visualisasi yang dapat menarik minat siswa dalam proses pembelajaran. Masyarakat suku melayu di Kabupaten Natuna masih melestarikan salah satu budaya yakni menganyam beberapa produk yang digunakan sebagai alat untuk menunjang kebutuhan sehari-hari. Pembelajaran yang dilakukan menggunakan media dapat membuat siswa tertarik dalam proses pembelajaran memadukan antara sebuah tradisi atau kebudayaan dengan media pembelajaran yang menarik dapat membantu siswa lebih mengenal kebudayaannya sendiri dan membuatnya tertarik untuk mempelajarinya. Penelitian ini bertujuan untuk mengetahui kevalidan ensiklopedia tanaman anyaman suku Melayu di Kecamatan Bunguran Selatan, Kabupaten Natuna Dan untuk mengetahui respon siswa terhadap ensiklopedia tanaman anyaman suku Melayu di Kecamatan Bunguran Selatan, Kabupaten Natuna. Penelitia ini dilakukan di Kabupaten Natuna, Kecamatan Bunguran Selatan. Metode yang digunakan merupakan desain  and development (D&D). Berdasarkan hasil penelitian yang telah dilakukan didapati media ensiklopedia tanaman anyaman suku melayu kabupaten natuna telah memenuhi aspek validitas dimana aspek media sebesar 95.29% (Sangat Valid), aspek materi 96.67%(sangat valid), dan aspek kebahasaan 97,27%(sangat valid). Peserta didik memberikan respon yang sangat baik dimana pada uji coba skala kcil sebesar dan skala besar mendapatkan nilai skala kecil 91.04% (Sangat baik) dan skala besar 93.50 (Sangat baik). Dapat disimpulkan ensiklopedia tanaman anyaman suku melayu di kabupaten natuna dapat dimanfaatkan sebagai media pembelajaran biologi yang masuk ke dalam materi keanekaragaman hayati
 
 
Keywords: Pengembangan, Ensiklopedia,tanaman anyaman,suku melayu,Natuna
Negotiating Indigenous participation and heritage at a multicultural festival
Authors: Kjørven Ole Kolbjørn , Dewilde Joke , Skrefsrud Thor-André
Published: October 2024

This article investigates how Indigenous participation and heritage are negotiated at a multicultural festival in Norway. While such festivals respond to the call for meeting places that foster inclusion and belonging in society, researchers have warned against promoting superficial understandings and essentialism. Based on fieldwork and semi-structured interviews with festival management and Greenlandic participants, we found that Indigenous participation and heritage were negotiated along three lines. First, participants shared enthusiasm for the festival and its inclusive vision. Second, they showed in different ways the imperative of understanding the complexity of Indigeneity as a diverse and multifaceted experience. Third, in response to the festival management’s call for participation, one acted as a curator while others became silent consultants. We argue that the experience of both festival management and Greenlanders could have been significantly deepened by a more profound and shared knowledge of the nature of Indigeneity.
O que dizem as pesquisas acadêmicas sobre a gestão democrática nas unidades de educação infantil (2012-2022)
Authors: Fritsche Simone , Fritsche Simone , Ferreira Valéria Silva
Published: October 2024

Com o objetivo de apreender qual tem sido o foco dos estudos acadêmicos sobre a gestão democrática no contexto da educação infantil, este artigo de revisão apresenta um mapeamento das pesquisas acadêmicas na área da educação infantil, desenvolvidas em teses e dissertações, no período de 2012 a 2022. Esta revisão bibliográfica analisa os trabalhos selecionados, classificando-os de acordo com suas principais temáticas, e apresenta as discussões que envolvem aspectos da gestão das unidades de educação infantil. Partindo das premissas desses trabalhos, temos a possibilidade de vislumbrar parte do horizonte a ser desbravado neste campo, além de constatar a urgência de articulação entre o conhecimento produzido e a prática daqueles que atuam na gestão do espaço educativo das crianças.
Necropolítica: uma análise jurídica dos seus desdobramentos para a evasão escolar no Brasil
Authors: Teixeira Luana Letícia da Silva , Santos Teófanes Carnaúba dos
Published: October 2024

A presente pesquisa tem como objetivo compreender o processo de evasão escolar no Brasil, analisando o aspecto jurídico existente nas relações e interações sociais que permeiam uma necropolítica enraizada em um cenário díspar e segregacionista de bases históricas e classistas, que promove a desigualdade de acessos, supressão de direitos e perseguição de corpos tidos por intoleráveis aos olhos da sociedade. A asserção metodológica visa a definição dos aspectos balizadores da pesquisa científica. Assim, se busca demonstrar por meio do auxílio das conceituações de alguns teóricos juntamente com o aspecto subjetivo inerente, os elementos estruturantes de uma base social e jurídica excludente, que seleciona as oportunidades e lima a construção de novas perspectivas para uma parcela da população já estipulada, em um sistema de decisões limitantes. Nessa perspectiva, a pesquisa proposta terá um caráter dogmático e explicativo-bibliográfico, analisando os elementos dispostos ao auxílio de uma mudança de cenários, em que os riscos não sejam a regra e que as bases sociais, familiares e educacionais estejam transponíveis ao conhecimento de direitos e deveres e a sua devida instituição, objetivando unir o que historicamente foi tido como malfazejo, execrando o caráter individualista da sociedade. Por conseguinte, objetiva-se utilizar como aporte teórico e como composição do conhecimento, os aspectos salutares de construção social trazidos por Agnes Heller em seu livro o cotidiano e a história, Achille Mbembe em seu livro Necropolítica, Kabengele Munanga, como organizador do livro superando o racismo na escola e os aspectos dispostos por Tomaz Tadeu da Silva em seu livro identidade e diferença: a perspectiva dos estudos culturais, bem como as legislações pátrias que cooperam na perquirição por uma sociedade de iguais. Aspirando, dessa forma, a construção de uma linha de raciocínio e cognição para que os aspectos postos à deriva não fiquem encobertos e venham à tona para serem limados, visando assim por meio de uma análise bibliográfica prescritiva o alcance de um fim comum: a atenuação dos malefícios trazidos pela falta de acessos, escolha de privilégios e apontamento de alvos. Assim, o limiar social salienta as escolhas que deveriam ser realizadas de forma natural e universalizada, mas que ocorrem por uma parcela ínfima da população. Nesse sentido, a alteração de estruturas dispostas de forma secular só pode ser realizada mediante conhecimento, indagações, apontamentos e estipulações e a pesquisa é o ambiente propício para tal ato, no sentido de buscar novas nuances para um cenário que não pode mais ser de escolhas benéficas restritas e alvos apontados em direção aos mesmos rostos.