bluuebunny/crossref_metadata_2025 huggingface dataset:
Medical Specialty Recommendations by an Artificial Intelligence Chatbot on a Smartphone: Development and Deployment (Preprint)
Authors: Lee Hyeonhoon , Kang Jaehyun , Yeo Jonghyeon
Published: January 2021

BACKGROUND

The COVID-19 pandemic has limited daily activities and even contact between patients and primary care providers. This makes it more difficult to provide adequate primary care services, which include connecting patients to an appropriate medical specialist. A smartphone-compatible artificial intelligence (AI) chatbot that classifies patients’ symptoms and recommends the appropriate medical specialty could provide a valuable solution.

OBJECTIVE

In order to establish a contactless method of recommending the appropriate medical specialty, this study aimed to construct a deep learning–based natural language processing (NLP) pipeline and to develop an AI chatbot that can be used on a smartphone.

METHODS

We collected 118,008 sentences containing information on symptoms with labels (medical specialty), conducted data cleansing, and finally constructed a pipeline of 51,134 sentences for this study. Several deep learning models, including 4 different long short-term memory (LSTM) models with or without attention and with or without a pretrained FastText embedding layer, as well as bidirectional encoder representations from transformers for NLP, were trained and validated using a randomly selected test data set. The performance of the models was evaluated on the basis of the precision, recall, F1-score, and area under the receiver operating characteristic curve (AUC). An AI chatbot was also designed to make it easy for patients to use this specialty recommendation system. We used an open-source framework called “Alpha” to develop our AI chatbot. This takes the form of a web-based app with a frontend chat interface capable of conversing in text and a backend cloud-based server application to handle data collection, process the data with a deep learning model, and offer the medical specialty recommendation in a responsive web that is compatible with both desktops and smartphones.

RESULTS

The bidirectional encoder representations from transformers model yielded the best performance, with an AUC of 0.964 and F1-score of 0.768, followed by LSTM model with embedding vectors, with an AUC of 0.965 and F1-score of 0.739. Considering the limitations of computing resources and the wide availability of smartphones, the LSTM model with embedding vectors trained on our data set was adopted for our AI chatbot service. We also deployed an Alpha version of the AI chatbot to be executed on both desktops and smartphones.

CONCLUSIONS

With the increasing need for telemedicine during the current COVID-19 pandemic, an AI chatbot with a deep learning–based NLP model that can recommend a medical specialty to patients through their smartphones would be exceedingly useful. This chatbot allows patients to identify the proper medical specialist in a rapid and contactless manner, based on their symptoms, thus potentially supporting both patients and primary care providers.
Preliminary Outcomes of an Ecological Momentary Intervention for Social Functioning in Schizophrenia: Pre-Post Study of the Motivation and Skills Support App (Preprint)
Authors: Fulford Daniel , Gard David E , Mueser Kim T , Mote Jasmine , Gill Kathryn , Leung Lawrence , Mow Jessica
Published: January 2021

BACKGROUND

People with schizophrenia and other serious mental illnesses often lack access to evidence-based interventions, particularly interventions that target meaningful recovery outcomes such as social functioning and quality of life. Mobile technologies, including smartphone apps, have the potential to provide scalable support that places elements of evidence-based interventions at the palm of patients’ hands.

OBJECTIVE

We aim to develop a smartphone app—called Motivation and Skills Support—to provide targeted social goal support (eg, making new friends and improving existing relationships) for people with schizophrenia enrolled in a stand-alone open trial.

METHODS

In this paper, we presented preliminary outcomes of 31 participants who used the Motivation and Skills Support app for 8 weeks, including social functioning pre- to postintervention, and momentary reports of treatment targets (eg, social motivation and appraisals) during the intervention.

RESULTS

The findings suggest that the intervention improved self-reported social functioning from baseline to treatment termination, particularly in female participants. Gains were not maintained at the 3-month follow-up. Furthermore, increased social functioning was predicted by momentary reports of social appraisals, including perceived social competence and the extent to which social interactions were worth the effort.

CONCLUSIONS

The implications of these findings and future directions for addressing social functioning in schizophrenia using mobile technology have been discussed.

CLINICALTRIAL

ClinicalTrials.gov NCT03404219; https://clinicaltrials.gov/ct2/show/NCT03404219
Kajian Metode Aplikasi Sinkronisasi Birahi menggunakan PGF2α pada kambing terhadap kualitas estrus, konsentrasi progesterone dalam darah dan tingkat kebuntingannya
Authors: Budiyanto Agung
Published: January 2021

A study of the application method of estrus synchronization with prostaglandin 2 alpha (PGF2α) preparations in local goats in Yogyakarta to determine the effectiveness of estrus synchronization based on the quality of estrus, the concentration of the hormone progesterone in the blood and the level of pregnancy have been done. The low pregnancy rate in goats is caused by a short time of heat and mating behavior that is not clear, resulting in low reproductive performance. The application of lust synchronization technology is expected to solve this problem. Prostaglandin F2α (PGF2α) is commonly applied in Indonesia intramuscularly (IM), while other methods have no known scientific data on the effectiveness of this method. This study used two methods, namely intramuscular (IM) as a control and intravaginal sponge (IS) method. The IM method is a standard method that is commonly used in synchronizing goat estrus, while the IS method with a smaller dose has never been studied scientifically and in detail. This study was to determine the effective dose required in the IS administration of PGF2α hormone in influencing the quality of estrus, progesterone hormone profile, and pregnancy and compared with IM application as a control. This study used 24 goats that had given birth, were not pregnant, aged 3-5 years, had an average weight of 40 kg and were healthy, divided into 3 treatment groups. Group 1 IM PGF2α hormone (8.25 mg / head), group 2 IS PGF2α hormone (5.5 mg / head) and group 3 IS PGF2α hormone (2.75 mg / head). Estrus detection was carried out by visual observation, mating using a trained male, testing progesterone levels with an ELISA kit and pregnancy examination with ultrasound. The results were analyzed using ANOVA and T-Test. The results showed that there was no difference in estrous quality (P> 0.05) at the peak of estrus in each group. Progesterone levels in the IS group with a dose of PGF 5.5 and 2.75 mg / head indicated that the dose of 5.5 mg / head was lower than that in the 2.75 mg / head group. The pregnancy rate of the IM group was not significantly different from the IS group. The conclusion of this research is that synchronization of estrus using PGF2α by IS would to be effectively produce the quality of lust, the level of progesterone in the blood and pregnancy which are not different from the IM administration. The IS method can be applied to synchronization of goats in Indonesia at a lower cost, but the level of efficiency and effectiveness is not different from the IM method which uses a higher dose.
Пространственная семантика послелога деер в калмыцком языке
Authors:   Gorodovikov Kalmyk State University (11, Pushkin St., Elista 358000, Russian Federation), Lidzhieva Liudmila L. , Ubushieva Bamba E. , Mukabenova Zhanna A.
Published: January 2021

Introduction. The article examines spatial uses of the postposition деер in the Kalmyk language. The semantic system of postpositions that form postpositional constructions comprises a complex area of various relations. A remarkable place in the Mongolic languages is occupied by spatial meanings of postpositions, the postposition деер being a most common and productive one therein. Goals. The research aims to describe spatial meanings of the postposition деер in the Kalmyk language. Materials. The work analyzes data selected from various dictionaries, literary and journalistic texts included in the National Corpus of the Kalmyk Language, Kalmyk National Corpus, and the Kalmyk Digital Library. Results. This postposition is mentioned in all dictionaries of Mongolic languages and is a most common and productive lexical unit. It expresses a wide variety of relations resulting from its syntactic ties: spatial, temporal, comitative, target, and quantitative-restrictive values. Along with concrete, real relations this postposition in various speech situations acquires additional, sometimes very abstract meanings based its core seme. The spatial meanings of the postposition деер in the Kalmyk language are considered in detail. In addition to its main meaning — location or movement on the surface — this postposition indicates movement or performing an action over the surface of an object without reaching contact, in close vicinity, near a landmark, and also shows the direction of action. This postposition can express ‘event space’. Conclusions. The analysis of spatial relations expressed by the postposition деер shows a variety of transmitted meanings in various speech situations, as well as features of its use in the Kalmyk language.
Фотообразы буддистов Бурятии
Authors:   Institute for Mongolian, Buddhist and Tibetan Studies, Siberian Branch of the RAS, (6, Sakhyanova St., Ulan-Ude 670047, Russian Federation), Bazarov Andrei A. ,   Buryat State University (24A, Smolin St., Ulan-Ude 670000, Russian Federation)
Published: January 2021

Goals. The paper examines the issue of visual images in the everyday ritual practice of ordinary Buddhists in Buryatia. The relevance of studying rare Buddhist photographs as a historical and cultural source cannot be questioned, since this perspective reveals unknown aspects in the formation of Buryat identity and the role of Buddhism in this process. Materials. The work investigates the collection of rare photographs at the Institute for Mongolian, Buddhist and Tibetan Studies (Siberian Branch of the Russian Academy of Sciences) and photographs of the ritual complex ‘khoimor-gungurba’ collected during expeditions of the 1950-1970s and in the early 21st century. Results. A method (metalanguage) of describing Buddhist photo images was developed during preliminary works to clarify the mechanism of actualizing this material in Buddhist discourse, including elements as follows: a mechanism of image selection; cultural context; ritual and social goals; nature of materials; registration of believers’ reactions to visual images. The paper shows a close relationship between the local visual practice of Buddhists and the formation of Buryat identity from the late 19th towards the 21st century, which is concluded from a comparative analysis of the two databases. After a comparative reconstruction of the structures of the collections, the work argues that the everyday ritual practice of praying before these photos is an important aspect in the formation of local identity. The most interesting finding of the study is that pre-revolutionary images of Buryat Lamas are central in the culture of the photo-visual practices of Buryat Buddhists nowadays. The comparative analysis confirmed that a fundamental change in the transmission of the Buddhist tradition in Buryatia, social changes, and the economic situation led to a change in the development of the traditional Buddhist culture of the Buryats that currently prioritizes autocephaly and the preservation of ethnic identity.
Real-world healthcare resource utilization and costs of weekly versus every-2-week cetuximab in metastatic colorectal cancer
Authors: Pescott Chris P , Boutmy Emmanuelle , Batech Michael , Ronga Philippe , Lamy Francois-Xavier
Published: January 2021

Aim:
To compare healthcare resource utilization (HRU) and healthcare costs (HC) for every-2-week (Q2W) versus weekly (Q1W) cetuximab in metastatic colorectal cancer (mCRC).
Patients & methods:
Patients with mCRC receiving cetuximab plus chemotherapy in a line-agnostic setting. Cohort study of patients with mCRC treated with cetuximab and chemotherapy in IBM MarketScan. Analyses were weighted by inverse probability of treatment based on propensity score.
Results:
HRU was numerically lower with the Q2W versus Q1W regimen (weighted mean, 8.1 vs 9.5 encounters per-patient-per-month). The weighted average of HC was $17,653 and $16,469 per-patient-per-month for the Q2W and Q1W regimens, respectively; the difference between regimens decreased when restricting to CRC-related claims.
Conclusion:
HRU was lower and HC were similar between the Q2W and Q1W regimens.
Otras formas de defender el territorio: la revitalización cultural e identitaria del pueblo cochimí de Baja California
Authors: Velasco Pegueros Blanca Alejandra
Published: January 2021

Este artículo ofrece un acercamiento a las problemáticas territoriales de los pueblos nativos de Baja California, en específico de las y los descendientes del pueblo cochimí del desierto central de la península quienes, a raíz de la pérdida de sus derechos agrarios, y a pesar de haber sido considerados extintos durante mucho tiempo, se organizaron en un proceso de revitalización cultural e identitaria para luchar por su territorio. A lo largo de estas páginas intento dar cuenta de cómo a pesar de los cambios culturales y la desterritorialización, la  pertenencia territorial puede volverse un sólido emblema para la reconfiguración de la identidad  étnica y ser un elemento importante en la creación de nuevas formas de resistencia en  momentos de confrontación o disputa por el territorio.
Los proyectos a favor de las provincias del Reino de Guatemala en las Cortes de Cádiz
Authors: Benavides Barquero Manuel Jesús
Published: January 2021

El objetivo de este artículo es analizar los proyectos que las provincias del Reino de Guatemala enviaron a las Cortes de Cádiz. Se pretende matizar la teoría de la búsqueda de la autonomía frente a España usada para interpretar la acción de los diputados americanos en aquellas Cortes, en específico en lo referente a los proyectos. Al ser un tema poco estudiado, la mayor parte de las fuentes son de archivo, tratadas temáticamente por medio de una base de datos. El resultado ha ayudado a comprender mejor que la motivación no era la búsqueda de una autonomía frente a España sino una lucha para hacerse del poder a nivel interno por razones económicas, así como responder el porqué, a pesar de que la emancipación llegó sin derramamiento de sangre, estas provincias se dividieron hasta hacer fracasar al sistema
Debacle electoral y fractura interna en el Partido de la Revolución Democrática
Authors: Bolívar Meza Rosendo
Published: January 2021

En este artículo se analiza cómo y por qué se presentó la debacle electoral del Partido de la Revolución Democrática en México durante la coyuntura del proceso electoral de 2018, y cómo se relacionó esto con su fractura interna, lo cual generó oposición entre los grupos o corrientes que lo conforman. Inclusive se originó la separación de algunos de sus integrantes, producto de desacuerdos por la conducción política del partido en la selección de candidatos y por su política de alianzas, lo cual provocó tensiones al interior de los grupos parlamentarios y de éstos con su dirigencia nacional
Liposomes embedded with differentiating factors as a new strategy for enhancing DPSC osteogenic commitment
Authors:   University “G. d’Annunzio” Chieti-Pescara, 66100, Chieti, Italy, Gallorini M , Di Carlo R , Pilato S , Ricci A , Schweikl H , Cataldi A , Fontana A , Zara S
Published: January 2021

Human dental pulp stem cell (DPSC) differentiation toward the osteoblastic phenotype is enhanced when culture media are supplemented with differentiating factors, i.e. ascorbic acid, β-glycerophosphate and dexamethasone. Liposomes, spherical vesicles formed by a phospholipid bilayer, are frequently used as carriers for drugs, growth factors and hydrophobic molecules. The aim of this work was to speed up DPSC commitment to the osteogenic lineage by embedding differentiating factors within liposomes. Firstly, liposomes were prepared by rehydrating a phospholipidic thin film and characterised in terms of dimensions. Secondly, liposome-exposed DPSCs were characterised by their immunophenotypic profile. Levels of CD90 were significantly decreased in the presence of liposomes filled with ascorbic acid, β-glycerophosphate and dexamethasone (Lipo-Mix) with respect to normal differentiation medium (DM), while CD73 and CD29 expression were enhanced, suggesting osteogenic commitment. Additionally, an appreciable extracellular matrix deposition is detected. Thirdly, the Lipo-Mix formulation better increases alkaline phosphatase activity and levels of Collagen I secretion with respect to DM. In parallel, the new liposome formulation is capable of decreasing the release of H2O2 and of triggering a precocious antioxidant cell response, redressing the redox balance required upon mesenchymal stem cell commitment to osteogenesis. It can be therefore hypothesised that Lipo-Mix could represent a suitable tool for clinical regenerative purposes in the field of tissue engineering by speeding up DPSC osteogenic commitment, mineralised matrix deposition and remodelling.
La justicia como imparcialidad, progreso y perfección
Authors: Otero Angelini Diego Alejandro
Published: January 2021

In this article I analyze the justification of rawlsian anti-perfectionism, present in both A Theory of Justice and Political Liberalism. My aim is to show how justice as fairness, Rawls's conception of justice, lacks stability because of it. As an alternative to his anti-perfectionism, I propose, in the second part, the idea of progress as practical perfectionism by John Dewey. I argue that a perfectionist liberalism of this kind does not undermine reasonable pluralism as Rawls argued. Also I argue that it is indispensable to establish a liberal society that is stable. In the end, I briefly show how the private sphere could be affected once the idea of progress is part of a conception of liberal justice.
On the correctness of problem solving in ancient mathematical procedure texts
Authors: Bacelar Valente Mario
Published: January 2021

It has been argued in relation to Old Babylonian mathematical procedure texts that their validity or correctness is self-evident. One “sees” that the procedure is correct without it having, or being accompanied by, any explicit arguments for the correctness of the procedure. Even when agreeing with this view, one might still ask about how is the correctness of a procedure articulated? In this work, we present an articulation of the correctness of ancient Egyptian and Old Babylonian mathematical procedure texts – mathematical texts presenting the solution of problems. We endeavor to make explicit and explain how and why the procedures are reliable over and above the fact that their correctness is intuitive.
Composición, identidad y cardinalidad
Authors: Briceño Sebastián
Published: January 2021

In this article I attempt to give an account of the thesis according to which composition is identity and of the criticisms that might be formulated against it. According to a weak version of the thesis, composition, in virtue of being analogous in important respects to identity, is as ontologically innocent as identity. According to the strong version of the thesis, composition is literally a species of the generic relation of identity, and is as ontologically innocent as any species of identity. As we will see, the weak version begs the question or incurs in a non sequitur; and the strong version is incoherent and faces a dilemma. Thus, composition is not identity: one thing cannot be identical to many things.
Fundamentos de la explicación en ciencias sociales: revisitando el constructivismo de Niklas Luhmann (20 años después)
Authors: Gibert Galassi Jorge , Venables Juan Pablo
Published: January 2021

In this work, it is argued that one of the foundations of NiklasLuhmann’s theory of social systems, namely that it has no ontology, would prevent the elaboration of explanations in sociology. Because the theory has a formal-logical foundation, which does not presuppose ontology, there are insurmountable obstacles to achieving this objective. For this reason, it is valid to wonder about the merit of a theory that, after 20 years, insists on not aligning itself with ontological premises in a robust way and suggests, therefore, a refusal to integrate sociology within the set of factual sciences. However, we think that the richness of Luhmann’s work allows a dialogue with the mainstream of contemporary theoretical practice. Three rules about what “should not be done” are revalidated from this analysis to philosophically base a theory in sociology and a key suggestion to overcome the problem of explanation in Luhmann’s sociology: social science seeks and directs its activity towards discovery and the use of substantive, real distinctions that also enrich the factual content of statements about social reality.
Cien años de Metafísica dentro de la tradición filosófica analítica. Introducción a la sección monográfica sobre metafísica analítica contemporánea
Authors: Rossi Carlo
Published: January 2021

Introduction to the monographic section on contemporary analytic metaphysics
Arquitetura da Informação para processos de negócio: um caminho para a governança de dados
Authors: Brandt Mariana Baptista , Vidotti Silvana Aparecida Borsetti Gregorio
Published: January 2021

As organizações produzem e consomem dados e informações cotidianamente em seus processos de negócio. Os dados são produzidos, alimentados, consultados, analisados e transformados ao longo das atividades e operações, e se constituem em uma fonte de informação essencial para o desenvolvimento das instituições. Os processos de negócios estão presentes em todas as atividades das organizações, mesmo que não formalizados. As instituições em seus diversos setores, como financeiro, recursos humanos, serviços gerais, diretorias e informática, possuem rotinas, processos e tarefas que são denominados processos de negócio. Essa investigação pauta-se no seguinte questionamento: como gerir esses dados adequadamente em um processo de negócios para a governança de dados? Para que a governança seja implementada, é necessária uma estrutura na qual os dados sejam mapeados, organizados, documentados e geridos. Nesse contexto apresenta-se a Arquitetura da Informação para Processos de Negócio como uma metodologia de Arquitetura da Informação que parte do processo de negócio para obter as informações mais importantes dos processos e representá-las, por meio de metadados de negócio, os quais serão registrados e descritos por atributos, configurando requisitos de informação. Desse modo, observa-se que a Arquitetura da Informação para Processos de Negócio deve ser o ponto de partida para a construção dos sistemas de informação que dão suporte ao negócio. Assim, fornecem insumos para a gestão dos dados e informações e para a governança de dados, por meio de seus entregáveis.

Palavras-chave: Arquitetura da Informação. Processos de Negócio. Arquitetura da Informação para Processos de Negócio. Metadados de Negócio.
Roma no Período Agustano: a construção material e simbólica da capital do mundo conhecido
Authors: Cunha Macsuelber de Cássio Barros da
Published: January 2021

Otávio Augusto se vangloriava de ter transformado Roma de uma cidade de tijolos para uma de mármore. Neste trabalho, dedicamos nossa atenção à estrutura material que deu sustentação à construção e ao desenvolvimento do poder de Augusto, ou seja, à cidade de Roma e às suas construções. Temos como objetivo demonstrar a importância conferida ao solo sagrado de Roma, bem como o relevante papel que teve enquanto centro do poder e suporte para o desenvolvimento de uma arquitetura monumental; tratamos também sobre a visão de Roma enquanto capital do mundo conhecido, o que estava expresso de modo material em determinadas construções do período.
Deep Imputation on Large-Scale Drug Discovery Data
Authors: Irwin Benedict , Whitehead Thomas , Rowland Scott , Mahmoud Samar , Conduit Gareth , Segall Matthew
Published: January 2021

More accurate predictions of the biological properties of chemical
compounds would guide the selection and design of new compounds in drug
discovery and help to address the enormous cost and low success-rate of
pharmaceutical R&D. However this domain presents a significant
challenge for AI methods due to the sparsity of compound data and the
noise inherent in results from biological experiments. In this paper, we
demonstrate how data imputation using deep learning provides substantial
improvements over quantitative structure-activity relationship (QSAR)
machine learning models that are widely applied in drug discovery. We
present the largest-to-date successful application of deep-learning
imputation to datasets which are comparable in size to the corporate
data repository of a pharmaceutical company (678,994 compounds by 1166
endpoints). We demonstrate this improvement for three areas of practical
application linked to distinct use cases; i) target activity data
compiled from a range of drug discovery projects, ii) a high value and
heterogeneous dataset covering complex absorption, distribution,
metabolism and elimination properties and, iii) high throughput
screening data, testing the algorithm’s limits on early-stage noisy and
very sparse data. Achieving median coefficients of determination,
R, of 0.69, 0.36 and 0.43 respectively across these
applications, the deep learning imputation method offers an unambiguous
improvement over random forest QSAR methods, which achieve median
R values of 0.28, 0.19 and 0.23 respectively. We also
demonstrate that robust estimates of the uncertainties in the predicted
values correlate strongly with the accuracies in prediction, enabling
greater confidence in decision-making based on the imputed values.
Waste not, want not: microsatellites remain an economical and informative technology for conservation genetics
Authors: Hauser Samantha , Athrey Giridhar , Leberg Paul
Published: January 2021

Comparisons of microsatellite and single-nucleotide polymorphisms (SNPs)
have found that SNPs outperform microsatellites in population genetic
analyses, calling into the question the continued utility of
microsatellites in population and landscape genetics. Yet highly
polymorphic markers may be of value in species that have reduced genetic
variation. This study repeated analyses previously done using
microsatellites with SNPs developed from ddRAD sequencing in the
black-capped vireo source-sink system. SNPs provided greater resolution
of genetic diversity, population differentiation, and migrant detection
but could not reconstruct parentage relationships due to insufficient
heterozygosities. The biological inferences made by both sets of markers
were similar: asymmetrical gene flow from source populations to the
remaining sink populations. With the landscape genetic analyses, we
found different results between the two molecular markers, but
associations of the top environmental features (riparian, open habitat,
agriculture, and human development) with dispersal estimates were shared
between marker types. Despite the higher precision of SNPs, we find that
microsatellites effectively uncover population processes and patterns
and are superior for parentage analyses in this species with reduced
genetic diversity. This study illustrates the continued applicability
and relevance of microsatellites in population genetic research.
Genome assembly and methylome analysis of the white wax scale insect provides insight into sexual differentiation of metamorphosis in hexapods
Authors: Chen Hang , Lu Qin , Chen Xiaoming , Ling Xiaofei , Liu Pengfei , Liu Ni , Wang Weiwei , Zhang Jinwen , Qi Qian , Ding Weifeng , Zhang Xin , Feng Ying , Zhang Yurong , Chen Ming-Shun , King-jones Kirst
Published: January 2021

Scale insects are hemimetabolous, showing “incomplete” metamorphosis
and no true pupal stage. Ericerus pela, commonly known as the white wax
scale insect (hereafter, WWS), is a wax-producing insect found in Asia
and Europe. WWS displays dramatic sexual dimorphism, with notably
different metamorphic fates in males and females. Males develop into
winged adults, while females are neotenic and maintain a nymph-like
appearance, which are flightless and remain stationary. Here we report
the de novo assembly of the WWS genome with its size of 638.30 Mb
(69.68Mb for scaffold N50) by PacBio sequencing and Hi-C. From these
data, we constructed a robust phylogenetic analysis of 24,923 gene
families from 16 representative insect genomes, which indicates that
holometabola evolved from incomplete metamorphosis insects in the Late
Carboniferous, about 50 million years earlier than previously thought.
To study the distinct development of males and females, we analyzed the
methylome landscape in either sex. Surprisingly, WWS displayed high
levels of methylation (4.42% for males) when compared to other insects.
We observed differential methylation patterns for genes involved in
steroid and sesquiterpenoids production as well as related fatty acid
metabolism pathways. We show here that both males and females exhibit
distinct titer profiles for ecdysone, the principal insect steroid
hormone, and juvenile hormone (a sesquiterpenoid), suggesting that these
hormones are the primary drivers of sexually dimorphic features. Our
results provide a comprehensive genomic and epigenomic resource of scale
insects that provide new insights into the evolution of metamorphosis
and sexual dimorphism in insects.
Novija
historiografija o grkokatoličkoj Marčanskoj (Svidničkoj/Platejskoj) biskupiji i
crkvenoj uniji u Hrvatskoj
Authors: Kudelić Zlatko
Published: January 2021

Autor
analizira noviju domaću i inozemnu historiografiju o Marčanskoj
(Svidničkoj/Platejskoj) biskupiji i crkvenoj uniji na području Hrvatsko-slavonske
vojne krajine. Ukazuje na razlike u interpretacijama kod pojedinih autora i na
moguće izvore njihovih zaključaka.
Fractal approach to explanation of silkworm cocoon’s biomechanism
Authors: Wang Kang-Le , Yao Shao-Wen
Published: January 2021

Fractal calculus is an excellent tool to explaining natural phenomena in porous media. In this paper, we first give a simple introduction on He?s fractal derivative, and then it is used to establish a model for thermal conduction of silkworm cocoon reveal its biomechanism. The theoretical results obtained in this paper are helpful for the biomimetic design.
Estimation of shoulder width and neck girth based on 3-D point cloud data
Authors: Lu Xin , Guo Panpan , Liu Guolian
Published: January 2021

The 3-D point cloud map in the anthropometry has attracted intensive attention due to the availability of fast and accurate laser scan devices. Inevitably, there is a data deviation between 3-D measurement and manual tests. To address this problem, shoulder width and neck girth are accurately determined from 3-D point cloud, the two-scale fractal is used for 3-D point cloud simplification, and young female samples are used in our experiment to show the accuracy.
Accounting Research Opportunities for Cryptocurrencies
Authors: Vincent Nishani Edirisinghe , Davenport Stephan A.
Published: January 2021

During recent years, cryptocurrency has gained the attention of many large companies such as Facebook, Expedia, Apple, and Overstock to name a few. The acceptance and use of cryptocurrency in business transactions can have a major impact on a company's accounting system. However, accounting research exploring issues related to cryptocurrencies is sparse. Therefore, we identify research questions that the accounting profession should address concerning cryptocurrencies. We categorize these research questions using Rogers' theory of diffusion of innovation in an attempt to encourage and extend accounting research in cryptocurrencies to influence the design, development, adoption, implementation, and operation of the technology. We recommend that researchers take a more prescriptive approach to research, rather than a descriptive approach, given that cryptocurrency is in the infancy stage of development and adoption.
Investigating and Comparing the Effect of Teach-Back and Multimedia Teaching Methods on Self-Care in Patients With Diabetic Foot Ulcers
Authors: Satehi Somayyeh Babamir , Zandi Mitra , Derakhshan Homayoon Bana , Nasiri Maliheh , Tahmasbi Tahmineh
Published: January 2021

This study evaluated the effect of teach-back and multimedia teaching methods versus routine care on the self-care of patients with diabetic foot ulcers. Patients receiving either the teach-back or multimedia interventions had greater improvement in self-care scores than those receiving routine care. Both the teach-back and multimedia teaching methods were found to be effective in enhancing the self-care of people with diabetes.
Prevalence of and Characteristics Associated With Overbasalization Among Patients With Type 2 Diabetes Using Basal Insulin: A Cross-Sectional Study
Authors: Cowart Kevin , Updike Wendy H. , Pathak Rashmi
Published: January 2021

This article describes a cross-sectional analysis of 655 patients to determine the prevalence of and patient-specific characteristics associated with overbasalization in patients with type 2 diabetes. Overbasalization was defined as uncontrolled A1C (>8%) plus a basal insulin dose >0.5 units/kg/day. The period prevalence of overbasalization was found to be 38.1, 42.7, and 42% for those with an A1C >8, ≥9, and ≥10%, respectively. Those with an A1C ≥9% had the greatest likelihood of experiencing overbasalization. These results suggest that overbasalization may play a role in patients not achieving optimal glycemic control in type 2 diabetes.
Joint use of Ca – Modified Double-Strained RNA as an Immunostimulator with a Vaccine for the Prevention of Food andMouth Disease (FMD)
Authors: TH Markosyan
Published: January 2021

The purpose of this work is to study the effect of combined use of the immunostimulant preparation which is double-stranded Ca-modified RNA with inactivated FMD vaccine for cattle against A, O and Asia-1 subtypes of FMD. Preparation have been received from sodium nucleinate or allocated from a killer yeast of Saccharomices cerewisiae. The modification of Ca ions assayed by the addition of sterile solution of calcium chloride. Based on received data it can be concluded that the using of immunomodulator in cattle induces more early and high immune response. The FMD vaccine intramuscular administration together with the preparation provides high enough of an immune response and high titer of antibody maintained for a period of 90 days (time of observation).
The Development of Village level Geospatial Framework for "Digital India"
Authors:   GIS Cell, Motilal Nehru National Institute of Technology, Allahabad, Uttar Pradesh, India, Azad Dinesh Kumar , Singh A.K. ,   Civil Engineering Department, Motilal Nehru National Institute of Technology Allahabad, Uttar Pradesh, India
Published: January 2021

The Digital India is a programme of the Government of India with a vision to transform India into a digitally empowered society and knowledge economy. Digital land record of villages is one of the important components of information system which plays a vital role in making this type of society Land record system is primarily managed manually in the country using registers and cadastral maps in the form of papers, clothes which are very rough, tempered, torn and in a bad condition. Thus, the record keeping and updation of the village level information is a big challenge. Preserving, updating and retrieving these records needs integration of the information in a single framework. This paper presents the development of village level geospatial framework which highlights the three growth areas among nine pillars of Digital India. It encapsulates the digitization, geodatabase preparation, topology, and geospatial framework development using revenue (Khasara) maps, Google earth imagery data and GIS technology.
A Comparison of Accountability Models in School Counseling Programs
Authors: Mujiyati Mujiyati , Mayasari Shinta , Adiputra Sofwan
Published: January 2021

The purpose of this study is to analyze the strengths and weaknesses of each accountability evaluation model in order to make it easier for counselors to understand it. The method used is qualitative research that focuses on meanings, definitions, characteristics, symbols and explanations of the concepts learned. Research data is collected through literature review and document analysis. In this study, descriptive document analysis methods were used in data analysis. Descriptive analysis method is a method that aims to test the facts and meanings of research systematically. This model is formed based on different initial goals in the implementation of counseling services. The counselor can choose one of the models that are appropriate to the situation and easy to apply in his school. Accountability Evaluation Models of School Counseling Program has advantages and disadvantages of each. The counselor should choose one model that is appropriate to the situation and easy to implement in his school so that the implementation of the school counseling program can be measured and planned in the future.
CONCEPÇÕES DE EDUCAÇÃO E JUSTIÇA: articulação possível com a gestão democrática da escola
Authors: Hora Dinair Leal da
Published: January 2021

Após longo período pesquisando, orientando mestrandos e doutorandos e publicando sobre a temática da gestão democrática, durante a realização de um pós-doutoramento na Universidade do Minho, em Portugal, tive a oportunidade de participar da discussão realizada pelo Prof. Dr. Carlos Vilar Estevão, na disciplina que ministrava para as turmas de Mestrado em Ciências da Educação no Instituto de Educação a qual tratava de Educação e Justiça. Como para mim era um tema novo, passei a realizar as leituras indicadas pelo Dr. Estevão e fui buscar outras leituras para me apropriar dos conceitos fundantes da articulação que se estabelece entre educação e justiça, como escola justa, justiça complexa, justiça radical, entre outros e, assim, tentar construir uma aproximação possível com a gestão democrática. Quando retornei ao Brasil, apresentei os resultados desses estudos para os mestrandos do Programa de Pós-Graduação em Educação, Comunicação e Cultura da UERJ e ofereci o tema de pesquisa Educação e Justiça, recebendo quatro novos orientandos que pesquisaram a respeito de escola justa. A abordagem do conceito de justiça, que a retira do sentido jurídico-formal, incluindo-a no sentido eminentemente político, ético, filosófico, cultural e sociológico, permite compreender sua relação orgânica com os conceitos de igualdade, equidade, liberdade, mérito, poder, autoridade, entre outros, que condicionam, de modo particular, a maneira como pensamos a educação e a forma como as escolas se organizam para cumprirem suas finalidades. Assim, quero estabelecer com todos que me ouvem agora, uma discussão a respeito de Educação e Justiça, tendo como objeto as concepções de justiça.
Analytics in the publication of a scientific journal
Authors: Bolshakov Denis Yu.
Published: January 2021

It is shown that the analysis of editorial and publishing processes helps to estimate the time of passing manuscripts in the editorial office of a scientific journal and to control the contractor when performing technical work on literary editing and layout of articles in the journal. For analytics, the apparatus of probability theory and mathematical statistics is used, as well as time series for predicting the dynamics of incoming articles and predicting the prospects for their publication. Based on the results obtained, it is shown that the study of time indicators of the processes of arrival and acceptance of articles for publication, reviewing, literary editing, layout and distribution and receipt of license agreements allows you to plan the work on the filling of articles in journal issues for the year ahead, monitor the work of reviewers on the examination of articles sent to them and manage the contractor preparing issues for publication, when performing technical work. All the considered analytical methods are available for use by the editors of the scientific journal. To simplify the compilation and work with the proposed analytics tools, we recommend software for working with spreadsheets.
Contributorship, not authorship: use CRediT to indicate who did what
Authors: Holcombe Alex O.
Published: January 2021

Participation in the writing or revising of a manuscript is, according to many journal guidelines, necessary to be listed as an author of the resulting article. This is the traditional concept of authorship. But there are good reasons to shift to a contributorship model, under which it is not necessary to contribute to the writing or revision of a manuscript, and all those who make substantial contributions to a project are credited. Many journals and publishers have already taken steps in this direction, and further adoption will have several benefi This article makes the case for continuing to move down that path. Use of a contributorship model should improve the ability of universities and funders to identify effective individual researchers and improving their ability to identify the right mix of researchers needed to advance modern science. Other benefi should include facilitating the formation of productive collaborations and the creation of important scientifi tools and software. The CRediT (Contributor Roles Taxonomy) taxonomy is a machine-readable standard already incorporated into some journal management systems and it allows incremental transition toward contributorship.
A arte nas escolas-parque de Brasília: concepções do trabalho pedagógico
Authors: Lira Silva dos Santos de Vasconcelos Rafaella , Dittrich Wiggers Ingrid
Published: January 2021

O artigo objetiva conhecer as concepções do ensino de arte que permeiam o trabalho pedagógico das escolas-parque de Brasília. Por meio de revisão sistemática na produção acadêmica nacional em forma de teses, dissertações, livros e capítulos de livros, foram identificados 18 estudos entre o ano de fundação da primeira escola-parque de Brasília, 1960, e o ano de 2017. Para auxiliar a análise desses estudos, o artigo se baseia em textos de John Dewey e Anísio Teixeira, tendo em vista que seus pensamentos constituíram a gênese das escolas-parque. Na análise, foi possível perceber três concepções do ensino de arte: a) como referência de uma nova perspectiva pedagógica para a educação nacional; b) como elemento entrelaçador de culturas e construtor de uma identidade para a cidade de Brasília; e c) como mediador de autoexpressão, liberdade, resistência e emancipação.
Trabalho pedagógico nos cursos de licenciatura da Universidade Estadual de Londrina: metodologias em questão
Authors: Rocateli Adrielly , Aparecida Pires Franco Sandra , Miola Galvão Rosangela , Couto Guimarães Casagrande Fernanda
Published: January 2021

O artigo analisa o trabalho pedagógico desenvolvido por professores de dez cursos de licenciatura da Universidade Estadual de Londrina (UEL) no que concerne ao uso de metodologias em sala de aula. A pesquisa é descritiva, com abordagem dialética, e utilizou como instrumento para a coleta de dados questionário estruturado on-line enviado aos docentes. Na análise dos resultados, foram utilizados os dados obtidos pelo instrumento SPSS e pela escala Likert, com enfoque qualitativo dos gráficos para verificar o uso ou não de metodologias diléticas, visto que a pesquisa se embasa na teoria histórico-cultural. Os resultados indicam que os professores usam metodologias, e, alicerçados nelas, assumem o papel de mediadores para a transformação dos conceitos dos discentes, perfazendo o processo que consiste na ascensão do conceito cotidiano ao conceito científico.
Entrevista con Felipe Rodríguez
Authors: Díez Juan José
Published: January 2021

Durante diez años, el Comité Cívico por la Dignidad de la Guajira, en cabeza de Felipe Rodríguez, ha liderado diferentes procesos de movilización e integración ciudadana en el departamento de la Guajira. Surgió en 2010 como reacción a la propuesta del entonces presidente Juan Manuel Santos Calderón de modificar el antiguo régimen de regalías, que, entre otras cosas, implicaba una centralización de los ingresos percibidos por la explotación minera. A partir de esto se inició un proceso para articular sectores indígenas, sindicales, estudiantiles e incluso un sector de las clases dirigentes. Una vez articulados, se conformó el Comité bajo el nombre de Comité Departamental en Defensa de las Regalías y se realizaron jornadas de protesta el 9 de noviembre de 2010 y el 26 de mayo de 2011, nombradas por el dirigente Felipe Rodríguez como las Marchas en defensa de las tierras y las regalías.
Incidencia de los murales en la reapropiación del territorio en el municipio de San Carlos (Antioquia) entre 2009 y 2019
Authors: Osorio Vergara Felipe , Chalarca Suescum José David , Zapata Bedoya Luis Emmanuel
Published: January 2021

En este artículo se presenta al municipio de San Carlos, oriente del departamento de Antioquia, como caso de reapropiación territorial de los sitios, que eran reflejo del pasado violento que vivió dicho municipio durante el conflicto armado. Los muros, que antes eran usados por los actores armados para intimidar y amenazar, fueron resignificados mediante la práctica del muralismo para recuperar los lazos de los habitantes con su entorno. Los ciento cuatro murales que hay en el área urbana y rural de la localidad se han convertido en referente del turismo de memoria, y han aportado a diluir el estigma de pueblo violento atribuido a esta localidad antioqueña.
Proof vs Truth in Mathematics
Authors: Murawski Roman
Published: January 2021

Two crucial concepts of the methodology and philosophy of mathematics are considered: proof and truth. We distinguish between informal proofs constructed by mathematicians in their research practice and formal proofs as defined in the foundations of mathematics (in metamathematics). Their role, features and interconnections are discussed. They are confronted with the concept of truth in mathematics. Relations between proofs and truth are analysed.
Idea of Artificial Intelligence
Authors: Trzęsicki Kazimierz
Published: January 2021

Artificial Intelligence, both as a hope of making substantial progress, and a fear of the unknown and unimaginable, has its roots in human dreams. These dreams are materialized by means of rational intellectual efforts. We see the beginnings of such a process in Lullus’s fancies. Many scholars and enthusiasts participated in the development of Lullus’s art, ars combinatoria. Amongst them, Athanasius Kircher distinguished himself. Gottfried Leibniz ended the period in which the idea of artificial intelligence was shaped, and started the new period, in which artificial intelligence could be considered part of science, by today’s standards.
About Some New Methods of Analytical Philosophy. Formalization, De-formalization and Topological Hermeneutics
Authors: Kaczmarek Janusz
Published: January 2021

In this article I want to continue the characteristics of philosophical methods specific to analytical philosophy, which were and are important for Professor Jan Woleński. So I refer to his work on the methods of analytical philosophy, but I also point out a few new methods that have grown up in the climate of studies of philosophers, especially analytical ontologists. I will therefore describe the following methods: generalization, specialization, formalization, de-formalization and topological hermeneutics. Instead of the term “method” I use interchangeably the terms “operation” or “procedure”. I will show that each of these operations makes an important contribution to ontological investigations, and, in particular, to formal ontology.