bluuebunny/crossref_metadata_2025 huggingface dataset:
Numerical Analysis in Ultrasonic Elliptical Vibration Cutting (UEVC) Combined With Electrical Discharge Cutting (EDC) For Ti6Al4V
Authors: Kurniawan Rendi , Xu Moran , Li Chang Ping , Park Gun Chul , Kwak Ye In , Chen Jielin , Ko Tae Jo
Published: November 2021

This paper reports the numerical analysis results of ultrasonic elliptical vibration cutting (UEVC) combined with the electrical discharge cutting (EDC), called UEVC+EDC. UEVC delivers decreasing cutting forces, repressing side-burrs, and lowering tool wear. EDC is a cutting technique using a pulsed spark to remove material using thermal energy. Difficult-to-cut materials, such as Ti-6Al-4V, can be cut effectively by combining these two techniques. A numerical study was performed using ABAQUS finite element analysis (FEA) software by investigating the von Mises stress, cutting forces, and temperature. Numerical analysis was carried out by modifying the ultrasonic vibration frequency, distance of the discharge pulse, discharge voltage, and discharge pulse radius. UEVC+EDC was compared numerically and experimentally with regular cutting (NC) and UEVC in terms of cutting force and tool temperature. The results showed that the UEVC+EDC method could improve the cutting condition by reducing the cutting force and von Mises stress and increasing the tool temperature.
COVID-19-Related Distress Predicts Analog PTSD Symptoms After Exposure to an Analog Stressor
Authors: Friesen Edith , Michael Tanja , Schäfer Sarah K. , Sopp M. Roxanne
Published: November 2021

The long-term impact of the COVID-19 pandemic on mental health is only starting to emerge. Beyond direct effects on mental health, it is crucial to investigate how negative psychological responses to the COVID-19 pandemic might affect etiological processes of different mental disorders. In the current online study, we investigated whether a negative psychological response to the pandemic might predispose individuals towards posttraumatic stress disorder (PTSD) development after exposure to a non-COVID-19-related traumatic stressor. Moreover, we examined if these effects are mediated by the strength of associative fear learning during trauma. Using an established analog procedure, we demonstrate that COVID-19-related distress predicts analog PTSD symptoms of a non-COVID-19-related stressor and that these effects are fully mediated by the strength of associative fear learning during exposure to the analog stressor. As such, our findings indicate that negative psychological responses to the COVID-19 pandemic should be considered as an emerging pretraumatic risk factor.
Incident management assistant using artificial intelligence chatbots
Authors: R. Blaj
Published: November 2021

The implementation for the concept presented in this paper was inspired by the fact that producers or service providers who want to furnish an extraordinary experience of their product have to be available and to give support 24/7 to their customers. More and more companies are opting for Artificial Intelligent Chatbots as part of their customer service team. This project aims to optimize and automate support for customers using the ServiceNow platform with a chatbot. Customers will have their own personal assistant who will create, delete, or modify the incidents assigned to them, but can also be used for recreational purposes or weather forecasts. Users can communicate with the chatbot using natural language through various chat applications: Skype, Webex Teams or through an intelligent speaker. The objectives that are proposed: illustration of the chatbot concept, illustrating the notion of chatbot through different scenarios, approaches; integration and use of common messaging services; using a platform as a service, named Firebase; create or modify data streams structured as incidents through APIs.
Distributed database on blockchain technology for new era of electricity transactions
Authors: S. V. Oprea
Published: November 2021

The electricity retailers or suppliers promote business models focused on consumers-centred services except few of them. The reader could even doubt their interest in offering the most appropriate tariffs since lower tariffs imply lower revenue and consequently lower profit. No one-fit-for-all service can actively engage the electricity consumers. Most of the electricity consumers do not understand their consumption behaviour because they do not know it, they do not have real access to the consumption data. The current web portals do not share the consumption data with third parties, thus there is no market solutions. In this paper, we propose a distributed database architecture on blockchain technology for electricity transactions that innovate and increase the market competition in the era of digitalization enhancing the consumers awareness and transparent transitions.
Development of the naval medicine in Bulgaria
Authors: D. Draganova
Published: November 2021

Twenty years ago, when the post of ship physician was almost mandatory, ship doctors (especially in merchant navy and fishing vessels) were often considered unnecessary. To ensure health and treatment on board, every seaman needs to know the first aid basics. Well-equipped, competent medical staff will effectively cure most injuries on board and thus reduce the number of expensive and inconvenient helicopter evacuations, ship detours and port links. Marine medicine training has been launched for five years now and is unique to university education in Bulgaria.
Environment friendly population records system using biometric data and anonymous signatures
Authors: N. F. Antonie
Published: November 2021

The fast evolution of technology allowed our society to search for ways to increase efficiency and productivity. In some domains this increase in efficiency also lead to less waste, which in turn may lead to better environment protection. Such a domain is that of population records. One way to properly identify an individual is to keep a record of his biometric data. Unfortunately this method of identification is raising a lot of concerns regarding privacy and the protection of private data. This paper proposes a method of protecting biometric data by securing it with anonymous signatures. This will allow the use of that biometric data for identification purposes only and will not link it to individuals without their personal identification card (e.g. passport, ID card, etc.). It is the authors’ belief that this method will increase the number of people to opt for biometric documents which will reduce bureaucracy and implicitly reduce the use of consumable materials thus better protecting the environment.
Economic and technogical considerations on the 3d printing components in university laboratories made from students
Authors: M. D. Vasilescu
Published: November 2021

The scope of this research is to analyse the economic aspects of the 3D printing parts for making parts and functional sub-assemblies for different machinery. The author intends in this work to make a clarification on the economic approaches of processing FDM (Fused Deposition Modelling) and DLP (Digital Light Processing) materials which can be used for generating mechanically required items. The paper it is structured in 5 chapters. In the first chapter, there is an ordering of the materials based on the literature, but also from its own experience in generating parts by 3D printing. Synthesis is made both in terms of physical and mechanical properties, but also from the point of view of economic as well. It should be shown that the comparison will also be made from the point of view of 3D printing generation since two different printing processes are used both as the principle of generation and the way of obtaining the 3D parts. For generating, two printers will be used, which both constructively and functionally will be analysed, both as functionality and as component design possibilities. The second chapter affected to the ordering of technological parameters of 3D generation by printing the parts with defining the main technical parameters of generation of the parts. This step is important both to ensure the assembly conditions of the components, but also to the fact that the materials used to make the parts produce different comportment after the three directions in terms of contractions and the variation of the dimensions. The third chapter analyses the main ways of generating the parts with the presentation of some of the domain-specific elements generated by 3D printing with FDM and DLP. In the fourth chapter is presented the economic calculation program made with practical applications related to the parts generated in the previous chapter. The last chapter is allocated to the conclusions and comparisons from the technologicaleconomical point of view compared to other specific technologies for generating the analysed parts.
A wave energy system based on peristaltic pumping of air by sea waves
Authors: D. Ünsalan
Published: November 2021

Oscillating water column type of wave energy converters have attracted researchers and engineers working on the field of renewable energy systems, despite the problems caused by the alternating direction of air flow through the turbines. This problem has been circumvented by the use of single direction of rotation turbines such as Wells, Denniss-Auld and omnidirectional impulse turbines, albeit with rather low efficiencies. The authors have considered the usage of near-sinusoidal (cnoidal) form of sea waves as the drivers for the linear peristaltic pumping of air along a channel. The conceived device is an inverted U-shaped channel on a barge, aligned in the direction of wave and serves as a channel for the progress of waveform. Air is driven through the channel by peristaltic action to achieve a unidirectional air flow at the leeward end of the channel. An end-wall operated by a float experiencing heaving and surging motions at the leeward side of the channel prevents the escape of pumped air, which instead is directed to an upward duct leading to a turbine. Since the air flow is unidirectional, the use of more convenient air turbines compared to the ones used in oscillating water column devices are enabled. Air flow parameters with wave amplitudes exceeding and less than channel height above the calm water line are analysed using the Airy wave to demonstrate the feasibility of the proposed system analytically. It was found that the optimum solution was achieved when the channel top is at the calm water level
The principles of fluid flow within circular ducts of seismic dissipation device used in construction systems
Authors: F. D. Scheaua
Published: November 2021

The intensive development of the construction industry nowadays has made the impressive building projects ideas to become real today all over the world. There has been a constant increase in the height of the building or the opening between supporting pillars if we make reference to bridges or viaducts. These achievements are possible due to the quality of the materials, but also the use of the protection systems, which are designed to provide a good stability degree for structures to which they are mounted in time against the dynamic actions represented mainly by the seismic actions. It is presented in this paper the role of a hydraulic power dissipative system which, by mounting on a building structure has the capacity to limit the structural frames relative displacements induced by the ground seismic motion at a certain moment in time. The dissipation device design is based mainly on a cylinder type with piston and the operation involves the use of a working fluid with special viscosity and compressibility properties. In the case of an earthquake occurrence, the device ends receive the tendency to perform cyclic traction-compression movements involving in motion the piston inside the cylinder. The piston can perform translational movement only based on the forced circulation of the working fluid through the small diameter circular orifices made in the piston head, thus providing a significant energy consumption of the total energy induced by earthquake in the structure. The device's overall model and flow pattern of the working fluid through the piston circular orifices are shown, based on a numerical analysis performed on dissipation device virtual model in order to highlight the flow path-lines of the working fluid that would coincide with the real device model operation.
Estimation of economic damages caused by the flood risk
Authors: A. Dănilă
Published: November 2021

In recent years, we have become increasingly aware of the importance of factoring the risk to people, property, the overall economy and the environment from flooding into the planning system, and the role that good planning has in avoiding and reducing such risk that could otherwise arise in the future need to pro-actively manage flood risk. There are many areas, including towns and cities that are already at risk from periodic flooding. One of them is Jijia hydrographic basin is characterized by frequent and sharp variations of flow volumes and levels which lead to floods and flooding throughout the basin. Dorohoi town is located in this basin and experienced a significant flooding from a heavy rainfall event in June 2010. The article describes the undergoing work on model development to estimate the damage that was produced by this flash flood. Different land-use data sets have been used to represent the uncertainties in the exposure, value and susceptibility components. For the flood hazard component, inundation depth has been varied systematically to estimate the sensitivity of flood damage estimations to this component.
Port operations and cargo handling operations. Process based approach
Authors: M. Bucur
Published: November 2021

In line with the quality management principles applied within a functional settlement of an organization, unconcerned of the size or principal object of activity, port operators should be treated as operational entities carrying out specific activities, aiming to achieve specific objectives, that are prior determined but in dependence with their location and role determined alongside the port logistic chain. The process-based approach involves establishing the processes and sub-processes applied to achieve the port operator's entire set of objectives, functions and tasks. As with any business, the company aims at lowering costs, delivering better, consistent and predictable results, focusing on priority. These can be more easily achieved through a process approach that allows the systematic definition of the activities necessary to achieve the desired outcome, setting clear and quantifiable responsibilities for key management activities, analysing and measuring the capability of core activities, identifying links between key activities and the organization's functions, focusing on the elements that can improve the organization's activities (resources, methods and materials) and assessing the risks, consequences and impact of activities on all stakeholders. Carrying out the process map, identifying the data stream, establishing input and output data are the first steps applied in orderto achieve a process model that will further allow the identification of indicators to improve the quality of the services provided and consequently to ensure the satisfaction of customers and other stakeholders.
Symmetry-protected gates of Majorana qubits in a high-$T_c$ higher-order topological superconductor platform
Authors: Lapa Matthew F. , Cheng Meng , Wang Yuxuan
Published: November 2021

We propose a platform for braiding Majorana non-Abelian anyons based
on a heterostructure between a dd-wave
high-T_cTc
superconductor and a quantum spin-Hall insulator. It has been recently
shown that such a setup for a quantum spin-Hall insulator leads to a
pair of Majorana zero modes at each corner of the sample, and thus can
be regarded as a higher-order topological superconductor. We show that
upon applying a Zeeman field in the region, these Majorana modes split
in space and can be manipulated for braiding processes by tuning the
field and pairing phase. We show that such a setup can achieve full
braiding, exchanging, and arbitrary phase gates (including the
\pi/8π/8
magic gates) of the Majorana zero modes, all of which are robust and
protected by symmetries. As many of the ingredients of our proposed
platform have been realized in recent experiments, our results provide a
new route toward universal topological quantum computation.
COLORISM IN TONI MORRISONS GOD HELP THE CHILD
Authors: Ajay Makwana
Published: November 2021

The present paper has been specifically designed to scrutinize the aspect of colorism in Toni Morrisons well acclaimed novel God Help the Child. African American literature is an academic body of writing produced by African descendants residing in America. The literary canon of African- American literature emerged in late part of 18th century in oral forms like sermon, gospel, music, jazz, blues and spirituals. African American writers have deliberately expressed their painful agony, racial segregation, social injustice and ill treatment which they tolerated in white American society. Toni Morrison was a prolific female novelist of African-American literary writing. Morrisons eleventh novel God Help the Child prominently deals with colorism, racism and child abuse. Conceptually, the term Colorism was coined by Alice Walker to address the superiority of lighter or white skin over the dark. Colorism has its genetic roots in racism because without racism the standardization of color conflict would not be exist. The novel unfolds the story of Bride, also known as Lula Ann who is born with dark black color. She receives ill treatment by her own parents and gets negative rejection because of having black skin. Brides dark color ruins her golden childhood period. Louis Bridewell rejects Bride from accepting as his baby. Similarly, Sweetness breeds Bride with harsh treatment and cruelty. The research study will primarily focus on to address the color conflict faced by child protagonist Lula Ann.
Prevention and treatment of lactostasis and (or) mastitis in the pediatric area: practical aspects
Authors: Safina A. I.
Published: November 2021

Introduction. Incomplete breast emptying is the main cause of lactostasis, which can contribute to the development of mastitis. The article discusses the issues of prevention and treatment of lactostasis in breastfeeding mothers in the district covered by childhealth care: how to arrange breastfeeding, expression of breast milk, regime issues from the baby’s first days, as well as present-day knowledge on breast milk microbiota dysbiosis and an option of probiotic therapy. Clinical cases are presented.

Clinical case 1. A breastfeeding mother found breast lumps on the one side 2 weeks after her labour. Lactostasis was diagnosed, it was caused by inappropriate breastfeeding technique. The breastfeeding mother was provided with the recommendations for proper performance of breastfeeding technique and prescribed the drug therapy: ibuprofen 400 mg once at fever ≥ 38.5 ºC and Lactobacillus fermentum CEST5716 – 1 capsule once daily. On the 3rd day, her health state significantly improved, the pain reduced, the temperature returned to normal, the breast lumps practically disappeared, on the 5th day the pain and breast lumps completely disappeared.

Clinical case 2. A breastfeeding mother, first labour, 2 months have passed since her labour, exclusively breastfeeding on demand, complaints of pain in the left breast, local hyperemia 3 x 3 cm occurred, no breast lumps, local pain elicited by palpation, fever of 37.2 ºC. The breastfeeding mother was diagnosed with lactostasis, she was provided with recommendations for the arrangement of breastfeeding and expression of breast milk; not proscribed with antibacterial therapy, but the therapy with Lactobacillus fermentum CEST5716, 1 capsule once daily for 1 month. A day later, her health state improved: the pain reduced, the hyperemia disappeared, her body temperature returned to normal. The patient was recommended non-drug measures for preventing lactostasis and continuous administration of Lactobacillus fermentum CEST5716 – 1 capsule daily for 1 month.

Clinical case 3. A breastfeeding mother detected daily lactostasis in her right breast 3 months after her labour. It might had been caused by chest contusion before the onset of the 1st episode of lactostasis. Medical examination revealed calcifications in her breast duct. Against the background of non-drug therapy, the patient adminstered Lactobacillus fermentum CEST5716 – 1 capsule daily, which resulted in a positive effect in a week’s time. The follow-up observation showed that lactostasis completely resolved without relapses in a 1.5-months’ time.

Сonclusion. The correct breastfeeding technique is key to the prevention of lactostasis and mastitis, and the use of probiotic therapy Lactobacillus fermentum CEST5716 is an effective and safe drug treatment.
Clinical and echographic signs of acute kidney injury in premature babies born with very low and extremely low body weight
Authors: Mironova A. K. , Osmanov I. M. , Zakharova I. N. , Pykov M. I. , Tumanova E. L. , Morozov S. L. , Vokuyeva T. I.
Published: November 2021

Introduction. One of the urgent issues in the first stage of nursing premature infants is acute kidney injury. The incidence of neonatal acute kidney injury in developing countries is 3.9/1000 live births, with 34.5/1000 among neonatal intensive care patients.

The aim of the study was to establish echographic signs of acute kidney injury in deeply premature infants in the neonatal period.

Materials and methods. 24 children with clinical and laboratory signs of acute kidney injury “AKI+” and 76 children without signs of acute kidney injury “AKI-“. All the children included in the study were born with a body weight of less than 1500 g and a gestation period of less than 32 weeks and were in the neonatal intensive care unit. To clarify the nature of the detected changes, a scientific analysis of the results of pathoanatomic studies of 55 deceased preterm infants was carried out.

Results. In all children from the “AKI+” group, there was a pronounced diffuse-uneven increase in the echogenicity of the parenchyma, there was a depletion of the vascular pattern in the subcapsular zone and/or in the cortical layer of the parenchyma, in 25% of patients on the 5th-15th day of life, anechogenic formations without signs of blood flow, with a diameter of 1-3 mm in the cortical layer were noted. The changes had a bilateral nature of the lesion, with further observation they were gradually reduced and by 3 ± 2 months of life they were not determined during ultrasound of the kidneys.

Discussion. Acute kidney injury is an urgent problem of preterm infants born with very low and extremely low body weight. The article presents the results of ultrasound examination of the kidneys in comparison with clinical and laboratory indicators and the results of pathomorphological studies. As a result of the study, the most characteristic ultrasound signs of acute kidney injury were identified, which are an uneven diffuse increase in the echogenicity of the renal parenchyma, small anechoic avascular inclusions (cysts) of the parenchyma, depletion of renal blood flow.

Conclusions. Renal ultrasonography is an informative method, but echographic changes may be labile depending on the clinical course of the disease, and the absence of anechogenic masses in the parenchyma may be due to technical limitations of the ultrasonography method. It requires further monitoring and continued vigilance of the pediatrician and pediatric nephrologist.
Acute otitis externa in children: causes, diagnosis, treatment, clinical report
Authors: Kirichenko I. M. , Popadyuk V. I. , Kozlova N. S.
Published: November 2021

Acute otitis externa is a common disease in the pediatric population, characterized by diffuse inflammation of the external auditory canal. Typical symptoms of acute otitis externa include otology, itching, congestion, and a feeling of fullness in the sore ear. In the case of active inflammation, the process can go to the tympanic membrane, and acute otitis media will join the external one. Primary therapy for diffuse uncomplicated acute otitis externa should include a local antimicrobial drug, without systemic antibiotic therapy. Topical therapy with antibacterial drugs in combination with anesthetics is the most rational. A clinical case of a 12-year-old patient with acute diffuse otitis externa and otitis media with effusion; acute nasopharyngitis; and adenoiditis, which was established based on anamnesis and clinical data is presented. Complex therapy was prescribed, which included local antibiotic therapy with a complex topical drug for the treatment of imperforated otitis externa and imperforated otitis media. At reexamination 5 days later, the patient demonstrated positive dynamics, pain in the left ear was eliminated. In cases of uncomplicated diffuse otitis externa, as well as in cases of its combination with otitis media with effusion, topical antibiotic therapy is a major priority. It should be borne in mind that the topical medication is more effective with the cleansing of the external auditory canal from inflammatory secretion. If it is used correctly, it would provide positive dynamics without systemic antibiotic prescription. It preserves the microbiome and mobilizes the body’s defenses. The application of complex topical antibiotic drugs can be widely recommended in pediatric practice.
Differentiated approach to correcting low vitamin D status in adolescent girls in Moscow
Authors: Zakharova I. N. , Soloveva E. A. , Tvorogova T. M. , Sugian N. G.
Published: November 2021

Introduction. The work is devoted to the study of vitamin D status in adolescent girls and the selection of adequate doses for its correction.

Study objective. To study the dynamics of calcidiol concentration in the blood serum against vitamin D3 intake and evaluate the effectiveness of correcting doses of vitamin in adolescent girls from Moscow.

Study design. A double-blind, placebo-controlled, prospective, randomized clinical study.

Materials and methods. The study involved adolescent girls aged from 11 to 17 years (n = 218) from I-II health groups, with determined serum level of 25(OH)D. Participants were randomly assigned to the main and control groups. The adolescent girls in the study group received vitamin D3 tablets, and the control group received a placebo. Study duration was 6 months. The dose of vitamin D3 was dependent on baseline serum caLcidioL levels and ranged from 800 IU to 2000 IU. Vitamin D status was redetermined in the girls who completed the treatment (n = 192).

Results. Initially, 96.4% of girls had a low vitamin D status, while vitamin D insufficiency was observed in 26.6%, deficiency in 57.8%, deep deficiency in 12%. The median level of 25(OH)D in the main group before taking the vitamin was 16.25 ng/ml, after taking - 24.1            ng/ml, in the control group - 17.9 and 11.4 ng/ml, respectively (p < 0.001). In the main group, an increase in the content of the metabolite was observed in 94.9% of the subjects, the initially identified pronounced deficit was completely absent.

Conclusions. A differentiated approach to prescribing different doses of cholecalciferon, depending on the baseline level of 25(OH)D, BMI and age, is an effective method for replenishing vitamin D deficiency in adolescents. The high probability of normalization of vitamin D status in certain age groups, mainly with the appointment of low corrective doses of cholecalciferol justifies the possibility of their use for 6 months or more in adolescents during puberty period.
Nutritional features of school children in the Siberian federal district
Authors: Tarmaeva I. Yu. , Pyrieva E. A. , Gmoshinskaya M. V. , Bogdanova O. G. , Tkachuk E. A. , Netunaeva E. A. , Safronova A. I. , Aleshina I. V.
Published: November 2021

Introduction. The study of schoolchildren’s nutrition features in different regions of the Russian Federation is one of the important tasks to health promotion of children by developing regional practices for optimization the nutrition of schoolchildren.

Objective. To study schoolchildren’s nutrition features in industrial cities of the Siberian federal district (Siberian FD).

Materials and methods. Specialized questionnaire was developed in order to study the nutrition organization of schoolchildren in various regions of the Russian Federation. 323 parents (legal representatives) of children aged 7-18 years living in the biggest industrial cities of south-eastern Siberia (the cities of Angarsk and Irkutsk) took part in the survey, based on the questionnaire. The obtained data was compared to the result of studies conducted in the Central federal district (Central FD), that included 162 observations. The frequency method was used to analyze the food consumption.

Results. The study established that consumption of milk, meat, cereals, potatoes, nuts, vegetables and fruits by children in the Siberian federal district was, all in all, significantly higher than in the Central federal district and in the Russian Federation in general. The nutrition of schoolchildren in the SFD is defined by a higher consumption of confectionery products, including chocolate, and such products as mayonnaise and margarine. It is noted that 75% of children in Angarsk and about 60% of children in Irkutsk regularly include chips and crackers in their diet and about 60% of children regularly consume fast food. At the same time, children living in Angarsk consume more food products with a high content of carbohydrates (cereals, potatoes, as well as added sugar in cookies, chocolates, sweet carbonated drinks), salt (in salted and dried fish), mayonnaise, and significantly less fermented dairy products and fresh fish compared to children in Irkutsk. Frozen products are more commonly consumed in the city of Angarsk than in Irkutsk. Physical development of children and its correlation with the variety of their diet was also assessed in the study. The assessment showed that children living in Angarsk have a significantly higher prevalence of obesity, which is a reflection of the irrational food diversity in their diets.

Conclusions. The obtained data reflect the need of the introduction of educational programs on healthy nutrition among schoolchildren and their parents, taking into account the regional specifics of nutrition.
Congenital insulin resistance in the practice of the pediatrician and pediatric endocrinologist -path to diagnosis
Authors: Nikitina I. L. , Todieva A. M. , Liskina A. S. , Plaksina A. О. , Petrova N. A. , Leonova I. A. , Kudryashova E. К. , Kostareva A. A. , Vasilyeva J. I.
Published: November 2021

Introduction. Hyperinsulinemic hypoglycemia in children is most commonly due to congenital hyperinsulinism. When hyperinsu-linemia is accompanied by fasting hypoglycemia and postprandial hyperglycemia, rare syndromes of severe insulin resistance, which include Rabson - Mendenhall syndrome, should be suspected. This article provides an analytical review of current data on this rare genetic pathology and presents a clinical case of a previously undescribed combination of Rabson-Mendenhall syndrome with mutations in the insulin receptor gene INSR in the compound heterozygous state with multiple congenital anomalies of other organs.

Clinical case. Patient N, 5.5 months old boy, with suspected congenital hyperinsulinism due to episodes of frequent severe hypoglycemia from the first day of life. At the age of 5 months, an episode of hypoglycemia up to 2.2 mmol/L was registered at an appointment with a pediatric endocrinologist. An examination was ordered, which found that against a background decrease in blood glucose to 1.9 mmol/L, C-Peptide level >5000 ng/mL, insulin level >300 lU/mL, cortisol - 971 nmol/L, TSH -3.88 mlU/L, free T4 - 10.53 pmol/L (10-23.2).

The importance of early diagnosis of severe insulin resistance to prevent developmental disorders in children is emphasized. The issue of organizing multiple effective monitoring of a patient’s glycemia required special attention in this clinical case. Due to the features of metabolism in young children, we abandoned flash glucose monitoring systems and used a modern glucose meter with an integration program with a mobile application and the ability to generate reports for subsequent analysis as a reliable means of glycemic control.

Summary. Based on the results of the genetic study in association with the clinical phenotype, age of debut, the patient was clinically diagnosed with Rabson-Mendenhall syndrome.

Discussion. The paradoxical nature of glycemic fluctuations (severe fasting hypoglycemia and postprandial diabetic hyperglycemia) is quite typical for syndromes of severe insulin resistance and should draw the attention of an informed primary care physician.

Conclusion. Careful attention to the symptoms of hypoglycemia, especially with a debut in the neonatal period, recurrent episodes, and the severity of the decrease in blood glycemia. If normal or elevated levels of insulin and C-peptide are detected against the background of hypoglycemia, the first thing to think about is congenital hyperinsulinism.
Omega-3 polyunsaturated fatty acids and vitamins A, D, E with increased mental and physical stress in schoolchildren
Authors: Starostina L. S.
Published: November 2021

Under current conditions of life with its intense rhythm, launch of new technologies, lack of time, both physical and mental workloads on a person increase. In these days, doctors more often report patients’ complaints of undue tiredness: they don’t feel rested even after a holiday and/or sleep. Today we tend to detect such manifestations not only in adults. Children also become less stress-resistant, more irritable due to an overabundance of information, and are prone to frequent infections. How can we help the growing generation cope with the increasing workloads? There’s no question, everyone knows about the need to use vitamins, but the right choice is not always possible. There are currently many single-component vitamin supplements and vitamin-mineral complexes. Some people prefer not to use industrially produced vitamins, but those contained in the natural products - fruits, vegetables, berries. But unfortunately, such a diet does not include the group of fat-soluble vitamins - A, D, E, K. In addition, far from everyone understands the importance of eating fatty acids. This article is devoted to the feasibility of additional intake of fat-soluble vitamins, polyunsaturated fatty acids (omega-3), their role in the body and deficiency symptoms. It has been established that the polyunsaturated fatty acid deficiency in the early period of life may trigger the development of cardiovascular disorders, problems associated with high cholesterol content, visual impairment, a drop of immunity, learning difficulties, and nervous system disorders in children in later years. Particular attention is paid to the omega-3 polyunsaturated fatty acid supplement combined with vitamins (A, E, D3), which enhance the positive effects. In addition, it does not cause negative emotions since it has a fruity taste.
Utilização de Algoritmo Genético para Estimação e Otimização de Parâmetros de um Controlador Adaptativo Direto Usado no Controle da Atitude de um Drone Quadrotor
Authors: Carvalho Lucas Jorge Caldeira , Prates Mauro de Oliveira , Campos Víctor Costa da Silva
Published: November 2021

O quadrotor é um tipo de VANT (Veículos Aéreos Não Tripulados) que possui diversas vantagens e aplicações. O acoplamento dinâmico e o comportamento altamente não-linear impõem um carácter desafiador ao controle destas aeronaves. Neste trabalho um controlador nebuloso adaptativo capaz de resolver um problema de rastreamento de trajetória é desenvolvido. Os parâmetros do controlador são estimados e otimizados pelo uso de um algoritmo genético, já que a utilização de controladores nebulosos implica no ajuste de vários parâmetros e, à medida que a complexidade do processo aumenta, torna-se difícil estabelecer a configuração ideal destes componentes de um sistema nebuloso. Através de resultados obtidos por simulação computacional, mostrou-se que o controlador projetado é eficiente para resolver o problema proposto e que o algoritmo genético conseguiu otimizar os seus parâmetros.
Some Aspects of the Influence of Population Diversity on the Performance of Differential Evolution
Authors: Carvalho Joao Claudio Chamma , Pinto Kalef Levy de Lima , Oliveira Roberto Celio Limão
Published: November 2021

This paper presents a study about some aspects of the influence of population diversity on the performance of the Differential Evolution technique. In order to accomplish this, the referred algorithm is tested with different benchmark functions widely used in the literature, and the performance results are analyzed and discussed by associating changes in the population diversity with changes in the evolution of the best solution over the generations. The objective of this work is to investigate the pattern of diversity behavior throughout the optimization process through graphs results and, then, evaluate how sensitive is the technique performance when associated with the population diversity behavior. This work can assist the implementation of new operators and strategies, which will permit the Differential Evolution technique to have a better performance.
Internet Comments as Delegitimization-Driven Discourse (a Case Study of the Fox News Materials on the Political Actions of the U.S. President Joe Biden)
Authors: Saveleva I. V.
Published: November 2021

The article introduces delegitimization as a macro-strategy of non-professional political discourse. The author studied comments on the site of the American Fox News to analyze the strategy of rational pessimism chosen by its readers as recipients of political news about the new president of the United States Joe Biden. The delegitimization discourse in the genre of Internet comments to political news proved to combine rational text production, emotional message, and an appeal to universal values. The strategy of rational pessimism manifested itself in the ideologies of the crises of democracy and presidential power. These cognitive-discursive units were actualized by both the broad extralinguistic context, i.e. the current political situation, and the immediate context, i.e. the publication aimed at discrediting Biden’s policy. The commentators' arguments about problems in the sphere of politics, economics, and business determined the interdiscursive nature of communication. While expressing pessimistic moods and negative attitude to the political actions of the U.S.President and the Democratic Party, the commentators appealed to the value categories of personal and state security.
Quantitative accuracy assessment of the revised sparse Gash model using distinct time-step climatic parameters
Authors: Li Yiran , Zhang Chuanjie , Niu Yong
Published: November 2021

Rainfall interception (I) can considerably influence the transport process of water. The revised sparse Gash model (RSGM) is a tool for determining the I, which assumes that the two climate parameters in the model are equal for all storms. However, few studies have provided additional cases to reexamine the correctness of this assumption and investigated the response of I of single storms to the time-step variability in climatic parameters. Hence, rainfall partitioning was measured during the growing season in 2017 for Pinus tabuliformis, Platycladus orientalis, and Acer truncatum in Northern China, and we ran RSGM on an event basis using different time-step climatic parameters (storm-based, monthly, and fixed) to estimate I. In summary, the modeling accuracy of both cumulative I and individual I was enhanced by increasing the time step of the climatic parameters in this study. These positively support the assumption in the RSGM. These results suggest that it is more appropriate to run the RSGM using fixed climate parameters to estimate I for these tree species during the growing season in northern China. Additionally, the assumption in the RSGM should be appealed to be further confirmed across the widest possible range of species, regions, and time scales.
Empowerment of fishermen family based on local wisdom
Authors: Ahdan S , Hadawiah Hadawiah , Mustafa Moh. Yahya
Published: November 2021

This study aims to examine socio-economic conditions and resources and community empowerment based on local wisdom to become a tourist village. It researched Maros Regency, South Sulawesi Province, Indonesia. The research method is observation, interviews, and documentation. As many as 18 informants were interviewed in-depth through purposive sampling to fishers. Cycle data analysis based on Huberman and Matthew with the help of Microsoft Excel program to create flowcharts and analyzed qualitatively. The results show that anglers who have a higher education positively affect fishermen's income. Informants with higher education levels have higher income levels as well. Socio-economically, fishers in Maros Regency generally work in the Minasa Upa river as fishermen. The Minasa Upa River as a source of community life is a potential development of beautiful river tourism and complements other tourism objects in Maros Regency. So, the management of the Minasa Upa river must be carried out based on local wisdom.
Successful pregnancy in a South African patient with end-stage renal disease with the use of thrice-weekly nocturnal haemodialysis
Authors: Stead Piers A. , Bapoo Nabeel A. , Grobbelaar Ronell , Miller Derek , Dumbril Douglas
Published: November 2021

Pregnancy outcomes in patients on chronic dialysis have improved as a result of the intensification of dialysis and improved perinatal care. We report the successful outcome of a pregnancy in a patient on chronic haemodialysis in Cape Town, South Africa. With intensification of her therapy using thrice-weekly, nocturnal haemodialysis the pregnancy was maintained until 34 weeks at which time a 1.86 kg baby boy was delivered by elective caesarean section. One year later the patient was doing well on maintenance haemodialysis and the baby was achieving his developmental milestones. This report highlights our ability to employ a multi-disciplinary approach and prolonged, nocturnal haemodialysis to support pregnant dialysis patients in the South African setting and achieve good outcomes for both mother and baby.
IgG4-related kidney disease: a rare cause of tubulointerstitial nephritis
Authors: John Thadathilankal J. , Pellizon Adriano , Bates Wiiliam D.
Published: November 2021

A 42-year-old black female was referred with unexplained renal failure. Initial radiological examination revealed a right adnexal inflammatory mass and bilateral hydronephrosis. The renal failure persisted despite the insertion of double J stents. A kidney biopsy showed a lymphoplasmacytic interstitial infiltrate that stained positive for IgG4. A diagnosis of IgG4-related tubulointerstitial nephritis (TIN) with pelvic-limited retroperitoneal fibrosis (RPF) was made and immunosuppressive treatment was initiated, with a good initial response to therapy. This report highlights the importance of considering RPF in cases of unexplained obstructive uropathy and of considering the diagnosis of IgG4-related disease when TIN is found in combination with other organ involvement.
The anthropic risks, climate change and coronavirus pandemic (COVID-19)
Authors: Gonçalves Carmen , Bertolami Orfeu
Published: November 2021

Risks have always been present throughout human history, however, today are qualitatively different, as many of them are anthropic (human-made). The fact that people are exposed to dangers for which they have no decision-making capacity depended on knowledge they often do not have in order to decide on possible acceptable risks. The pandemic situation we face now brings light on human-made risks; came and lifted the veil, if there were any doubts, about the impact on the quality of life on the Planet, as consequence of human decisions and behaviour. Two types of human-made risks will be addressed: climate change and the pandemic caused by the coronavirus (SARS-CoV-2); reflecting on the exposure of structural vulnerabilities, these risks bring forth the importance of social capital and social networks in reducing vulnerabilities, the investment in science and its dissemination, and prevention, as preparedness for future risks, promoting resilience. Thus, governance relationships between States, economic models and resilient communities will also be addressed.
Улучшение подъемных характеристик крыла со сверхкритическим профилем при использовании модулированного импульсного струйного актуатора
Authors: Abdolahipour Soheila , Mani Mahmoud , Shams Taleghani Arash
Published: November 2021

In this experimental investigation, a pulse flow control system on a high-lift device of a wing with a NASA SC(2)-0714 airfoil within the Reynolds number range of the take-off and landing phases, is proposed. In this study, an innovative method of signal modulation has been used in order to simultaneously exploit the benefits of both low and high excitation frequencies in one actuator driving signal that are known to be effective in separation control. It is observed that the lift and drag coefficients are improved due to the use of modulated pulse jets compared to the simple pulse jet.
Исследование гидродинамического сопротивления щелевого микроканала с текстурированной стенкой
Authors: Лобасов А.С. , Минаков А.В.
Published: November 2021

The results of numerical investigation of the hydrodynamic drag of a slit microchannel with a textured wall surface, as well as the pressure drop in such a channel and the effective slip length on the wall for various Reynolds numbers, are presented. The channel height was 10 µm, and the length varied from 25 to 500 µm. It was found that the pressure drop in the textured microchannel was less than in a conventional channel for any of its lengths. The dependences of the relative pressure drop, the friction factor, and the effective slip length on the Reynolds number were obtained for various channel lengths. A correlation that describes the dependence of the relative pressure drop on the Reynolds number for small channel lengths was proposed. The friction factor is described by a correlation of form 20 / Re.
Формирование наноразмерных пленок золота в условиях многократного автооблучения при ионно-лучевом осаждении
Authors: Шарко С.А. , Серокурова А.И. , Новицкий Н.Н. , Стогний А.И. , Кецко В.А.
Published: November 2021

Gold films with a thickness of several tens of nanometers were obtained on silicon and quartz substrates by ion-beam deposition – sputtering. It is shown that the predominant lateral growth of nanoscale metal layers along the substrate surface occurs under exposure to the high-energy component of the sputtered atoms flux. The decisive role in the nanometer gold film for-mation is played by the elastic collision of sputtered metal atoms with atoms of the substrate and the growing film. The application of the manifold deposition – sputtering operation allows sup-pressing the grain formation process and obtaining gold films with better characteristics than those with a single deposition.
Акустооптическая вейвлет-обработка биоэлектрических сигналов
Authors: Зайченко К.В. , Гуревич Б.С.
Published: November 2021

Wavelet analysis is one of the most efficient methods of the informative signals characteristics investigation. First shown the possibility of informative signals wavelet processing by means of the acousto-optic processor with time integration. The possibility of the realization of both power spectrum calculation and wavelet transform performance of bioelectric signals in the real time mode has been proved. The analysis is listed which describes its operation in different modes