bluuebunny/crossref_metadata_2025 huggingface dataset:
A Framework for Ultra Low-Power Hardware Accelerators Using NNs for Embedded Time Series Classification
Authors: Reiser Daniel , Reichel Peter , Pechmann Stefan , Mallah Maen , Oppelt Maximilian , Hagelauer Amelie , Breiling Marco , Fey Dietmar , Reichenbach Marc
Published: January 2022

In embedded applications that use neural networks (NNs) for classification tasks, it is important to not only minimize the power consumption of the NN calculation, but of the whole system. Optimization approaches for individual parts exist, such as quantization of the NN or analog calculation of arithmetic operations. However, there is no holistic approach for a complete embedded system design that is generic enough in the design process to be used for different applications, but specific in the hardware implementation to waste no energy for a given application. Therefore, we present a novel framework that allows an end-to-end ASIC implementation of a low-power hardware for time series classification using NNs. This includes a neural architecture search (NAS), which optimizes the NN configuration for accuracy and energy efficiency at the same time. This optimization targets a custom designed hardware architecture that is derived from the key properties of time series classification tasks. Additionally, a hardware generation tool is used that creates a complete system from the definition of the NN. This system uses local multi-level RRAM memory as weight and bias storage to avoid external memory access. Exploiting the non-volatility of these devices, such a system can use a power-down mode to save significant energy during the data acquisition process. Detection of atrial fibrillation (AFib) in electrocardiogram (ECG) data is used as an example for evaluation of the framework. It is shown that a reduction of more than 95% of the energy consumption compared to state-of-the-art solutions is achieved.
Pathogenesis, Immunology and Management of Dermatophytosis
Authors: Jartarkar Shishira R. , Patil Anant , Goldust Yaser , Cockerell Clay J. , Schwartz Robert A. , Grabbe Stephan , Goldust Mohamad
Published: January 2022

Dermatophytic infections of the skin and appendages are a common occurrence. The pathogenesis involves complex interplay of agent (dermatophytes), host (inherent host defense and host immune response) and the environment. Infection management has become an important public health issue, due to increased incidence of recurrent, recalcitrant or extensive infections. Recent years have seen a significant rise in incidence of chronic infections which have been difficult to treat. In this review, we review the literature on management of dermatophytoses and bridge the gap in therapeutic recommendations.
Mushroom Quality Related with Various Substrates’ Bioaccumulation and Translocation of Heavy Metals
Authors: Ab Rhaman Siti Maryam Salamah , Naher Laila , Siddiquee Shafiquzzaman
Published: January 2022

Mushrooms are popular due to the nutrition contents in the fruit bodies and are relatively easy to cultivate. Mushrooms from the white-rot fungi group can be cultivated on agricultural biomass such as sawdust, paddy straw, wheat straw, oil palm frond, oil palm empty fruit bunches, oil palm bark, corn silage, corn cobs, banana leaves, coconut husk, pineapple peel, pineapple leaves, cotton stalk, sugarcane bagasse and various other agricultural biomass. Mushrooms are exceptional decomposers that play important roles in the food web to balance the ecosystems. They can uptake various minerals, including essential and non-essential minerals provided by the substrates. However, the agricultural biomass used for mushroom cultivation is sometimes polluted by heavy metals because of the increased anthropogenic activities occurring in line with urbanisation. Due to their role in mycoremediation, the mushrooms also absorb pollutants from the substrates into their fruit bodies. This article reviews the sources of agricultural biomass for mushroom cultivation that could track how the environmental heavy metals are accumulated and translocated into mushroom fruit bodies. This review also discusses the possible health risks from prolonged uptakes of heavy metal-contaminated mushrooms to highlight the importance of early contaminants’ detection for food security.
What Is the Optimal Sodium Concentration in the Dialysate?
Authors: López-Gil Salvador , Madero Magdalena
Published: January 2022

Based on our experience in our hemodiafiltration unit we would recommend a personalized isonatremic dialysate bath. We currently prescribe 137 meq (isonatremic) or delta dialysate Na/serum Na less than 2 meq. In addition to the sodium prescribed in the dialysate, for the majority of our patients we do not restrict dietary sodium or water intake. The average sodium intake is 2775 mg per day and blood pressure is maintained without hypertensive medications. We acknowledge that part of the success for achieving dry weight may not be attributable only to the dialysate sodium but is likely the result of a combination of multiple factors such as convection therapy, cooling of dialysate, close monitoring of volume status during sessions with relative blood volume, presence of a nephrologist during all sessions and assessing volume status regularly with lung ultrasound and bioimpedance. In our experience, exercising during hemodialysis has additionally been associated with better hemodynamic status and less intradialytic hypotension. Moreover, we acknowledge there is little evidence to support a gradient dialysate to serum sodium of less than 2 meq and that our approach may not be optimal.
Identifying the Hot Spot Residues of the SARS-CoV-2 Main Protease Using MM-PBSA and Multiple Force Fields
Authors: Byun Jinyoung , Lee Juyong
Published: January 2022

In this study, we investigated the binding affinities between the main protease of SARS-CoV-2 virus (Mpro) and its various ligands to identify the hot spot residues of the protease. To benchmark the influence of various force fields on hot spot residue identification and binding free energy calculation, we performed MD simulations followed by MM-PBSA analysis with three different force fields: CHARMM36, AMBER99SB, and GROMOS54a7. We performed MD simulations with 100 ns for 11 protein–ligand complexes. From the series of MD simulations and MM-PBSA calculations, it is identified that the MM-PBSA estimations using different force fields are weakly correlated to each other. From a comparison between the force fields, AMBER99SB and GROMOS54a7 results are fairly correlated while CHARMM36 results show weak or almost no correlations with the others. Our results suggest that MM-PBSA analysis results strongly depend on force fields and should be interpreted carefully. Additionally, we identified the hot spot residues of Mpro, which play critical roles in ligand binding through energy decomposition analysis. It is identified that the residues of the S4 subsite of the binding site, N142, M165, and R188, contribute strongly to ligand binding. In addition, the terminal residues, D295, R298, and Q299 are identified to have attractive interactions with ligands via electrostatic and solvation energy. We believe that our findings will help facilitate developing the novel inhibitors of SARS-CoV-2.
Advancements of 2D Materials-Based Membranes
Authors: Othman Zakarya , Mahmoud Khaled A.
Published: January 2022

Our environment desperately needs creative solutions to limit the effect of industrialization’s fast rise and, consequently, to remediate vast amounts of harmful by-products and toxic exhausts [...]
The Effect of Ceramic Membranes’ Structure on the Oil and Ions Removal in Pre-Treatment of the Desalter Unit Wastewater
Authors: Rasouli Yaser , Parivazh Mohammad Mehdi , Abbasi Mohsen , Akrami Mohammad
Published: January 2022

Salts, organic materials, and hazardous materials can be found regularly in the effluent from a desalter unit of crude oil. These materials should be separated from the wastewater. Four kinds of inexpensive and innovative ceramic microfiltration membranes (mullite, mullite-alumina (MA 50%), mullite-alumina-zeolite (MAZ 20%), and mullite-zeolite (MZ 40%)) were synthesized in this research using locally available inexpensive raw materials such as kaolin clay, natural zeolite, and alpha-alumina powders. Analyses carried out on the membranes include XRD, SEM, void fraction, the average diameter of the pores, and the ability to withstand mechanical stress. Effluent from the desalter unit was synthesized in the laboratory using the salts most present in the desalter wastewater (NaCl, MgCl2, and CaCl2) and crude oil. This synthesized wastewater was treated with prepared ceramic membranes. It was discovered that different salt concentrations (0, 5000, 25,000, 50,000, 75,000, and 100,000 mg L−1) affected the permeate flux (PF), oil rejection, and ion rejection by the membrane. Results showed that in a lower concentration of salts (5000 and 25,000 mg L−1), PF of all types of ceramic membranes was increased significantly, while in the higher concentration, PF declined due to polarization concentration and high fouling effects. Oil and ion rejection was increased slightly by increasing salt dosage in wastewater due to higher ionic strength. Monovalent (Na+) and multivalent (Ca2+ and Mg2+) ion rejection was reported about 5 to 13%, and 23 to 40% respectively. Oil rejection varied from 96.2 to 99.2%.
Growth Mechanism of Periodic-Structured MoS2 by Transmission Electron Microscopy
Authors: Mukundan Arvind , Tsao Yu-Ming , Artemkina Sofya B. , Fedorov Vladimir E. , Wang Hsiang-Chen
Published: January 2022

Molybdenum disulfide (MoS2) was grown on a laser-processed periodic-hole sapphire substrate through chemical vapor deposition. The main purpose was to investigate the mechanism of MoS2 growth in substrate with a periodic structure. By controlling the amount and position of the precursor, adjusting the growth temperature and time, and setting the flow rate of argon gas, MoS2 grew in the region of the periodic holes. A series of various growth layer analyses of MoS2 were then confirmed by Raman spectroscopy, photoluminescence spectroscopy, and atomic force microscopy. Finally, the growth mechanism was studied by transmission electron microscopy (TEM). The experimental results show that in the appropriate environment, MoS2 can be successfully grown on substrate with periodic holes, and the number of growth layers can be determined through measurements. By observing the growth mechanism, composition analysis, and selected area electron diffraction diagram by TEM, we comprehensively understand the growth phenomenon. The results of this research can serve as a reference for the large-scale periodic growth of MoS2. The production of periodic structures by laser drilling is advantageous, as it is relatively simpler than other methods.
Investigation of Fast-Charging and Degradation Processes in 3D Silicon–Graphite Anodes
Authors: Zheng Yijing , Yin Danni , Seifert Hans Jürgen , Pfleging Wilhelm
Published: January 2022

The 3D battery concept applied on silicon–graphite electrodes (Si/C) has revealed a significant improvement of battery performances, including high-rate capability, cycle stability, and cell lifetime. 3D architectures provide free spaces for volume expansion as well as additional lithium diffusion pathways into the electrodes. Therefore, the cell degradation induced by the volume change of silicon as active material can be significantly reduced, and the high-rate capability can be achieved. In order to better understand the impact of 3D electrode architectures on rate capability and degradation process of the thick film silicon–graphite electrodes, we applied laser-induced breakdown spectroscopy (LIBS). A calibration curve was established that enables the quantitative determination of the elemental concentrations in the electrodes. The structured silicon–graphite electrode, which was lithiated by 1C, revealed a homogeneous lithium distribution within the entire electrode. In contrast, a lithium concentration gradient was observed on the unstructured electrode. The lithium concentration was reduced gradually from the top to the button of the electrode, which indicated an inhibited diffusion kinetic at high C-rates. In addition, the LIBS applied on a model electrode with micropillars revealed that the lithium-ions principally diffused along the contour of laser-generated structures into the electrodes at elevated C-rates. The rate capability and electrochemical degradation observed in lithium-ion cells can be correlated to lithium concentration profiles in the electrodes measured by LIBS.
Alveolar Echinococcosis—A Challenging Task for the Hepatobiliary Surgeon
Authors: Strohaeker Jens , Sulyok Mihaly , Koenigsrainer Alfred , Nadalin Silvio
Published: January 2022

(1) Background: Alveolar echinococcosis (AE) is an ultimately fatal disease, whose only curative treatment is surgery. Due to its late presentation extended liver resections are often necessary. The true benefit of extensive surgery has yet to be established; (2) Methods: We present a single center experience of 33 cases of Echinococcus multilocularis that have been treated at a high-volume hepatobiliary surgery center between 2004 and 2021. (3) Results: Of the 33 patients 24 patients underwent major liver resection (73%). In addition to the liver resection patients frequently underwent complex extrahepatic procedures such as lymphadenectomy (n = 21, 61%), vascular resections and reconstructions (n = 9, 27%) or resections and reconstruction of the extrahepatic bile duct (n = 11, 33%). Seven patients suffered from ≥ grade III complications (21%). Complete resection was achieved in 17 patients. Fourteen patients had R1 resections and two had macroscopic parasitic remnant (R2). Progressive disease was reported in three patients (The two R2 patients and one R1 resected patient). At a median follow-up of 54 months no mortality has occurred in our cohort; (4) Conclusions: Liver resection remains the gold standard for AE. Even in extensive disease the combination of complex resection and perioperative benzimidazoles can achieve favorable long-term outcomes.
Adaptive Wave-Front Shaping and Beam Focusing through Fiber Bundles for High-Resolution Bioimaging
Authors: Pochechuev Matvey S. , Fedotov Ilya V. , Solotenkov Maxim A. , Andreeva Maria S. , Lanin Aleksandr A. , Fedotov Andrei B. , Zheltikov Aleksei M.
Published: January 2022

We demonstrate an adaptive wave-front shaping of optical beams transmitted through fiber bundles as a powerful resource for multisite, high-resolution bioimaging. With the phases of all the beamlets delivered through up to 6000 different fibers within the fiber bundle controlled individually, by means of a high-definition spatial light modulator, the overall beam transmitted through the fiber bundle can be focused into a beam waist with a diameter less than 1 μm within a targeted area in a biotissue, providing a diffraction-limited spatial resolution adequate for single-cell or even subcellular bioimaging. The field intensity in the adaptively-focused continuous-wave laser beam in our fiber-bundle-imaging setting is more than two orders of magnitude higher than the intensity of the speckle background. Once robust beam focusing was achieved with a suitable phase profile across the input face of the fiber bundle, the beam focus can be scanned over a targeted area with no need for a further adaptive search, by applying a physically intuitive, wave-front-tilting phase mask on the field of input beamlets. This method of beam-focus scanning promises imaging speeds compatible with the requirements of in vivo calcium imaging.
Optimization of Hole and Electron Transport Layer for Highly Efficient Lead-Free Cs2TiBr6-Based Perovskite Solar Cell
Authors: Moiz Syed Abdul
Published: January 2022

The methylammonium lead halide solar cell has attracted a great deal of attention due to its lightweight, low cost, and simple fabrication and processing. Despite these advantages, these cells are still far from commercialization because of their lead-based toxicity. Among lead-free perovskites, cesium-titanium (IV) bromide (Cs2TiBr6) is considered one of the best alternatives, but it faces a lack of higher PCE (power conversion efficiency) due to the unavailability of the matched hole and electron transport layers. Therefore, in this study, the ideal hole and electron transport layer parameters for the Cs2TiBr6-based solar cell were determined and discussed based on a simulation through SCAPS-1D software. It was observed that the maximum PCE of 20.4% could be achieved by using the proper hole and electron transport layers with optimized parameters such as energy bandgap, electron affinity, doping density, and thickness. Unfortunately, no hole and electron transport material with the required electronic structure was found. Then, polymer NPB and CeOx were selected as hole and electron transport layers, respectively, based on their closed electronic structure compared to the simulation results, and, hence, the maximum PCE was found as ~17.94% for the proposed CeOx/Cs2TiBr6/NPB solar cell.
Az európai uniós forrásokból finanszírozott hitel- és tőkeprogramok menedzsmentjét érintő főbb változások a 2021-2027-es költségvetési időszakban
Authors: Bató Márk
Published: January 2022

Az Európai Unió kohéziós politikai forrásaiból származó támogatások megközelítőleg tíz százalékát használták fel pénzügyi eszközök formájában a 2014-20-as uniós költségvetési időszakban. A pénzügyi eszközök megnevezés Magyarország esetében hitel- és tőkejuttatás formájában nyújtott támogatást jelent. A 2021-27-es programokat még nem véglegesítették, de várhatóan ismét jelentős összegek felhasználására nyílik majd lehetőség pénzügyi eszköz formájában. Emiatt is lényeges áttekinteni azokat a változásokat, amelyek az uniós kohéziós politikai források felhasználási feltételeit érintik, a következő időszak fejlesztési politikájának végrehajtását meghatározzák a hitel- és tőkeprogramok terén. Mind az uniós, mind pedig a hazai induló szabályozási keretrendszer kialakítása lezárult, így az már megismerhető, és a további tervezés során kiindulópontként felhasználható. A tanulmányban áttekintjük a vonatkozó szabályozási keret főbb elemeit és azok várható gyakorlati következményeit.
Acompañamiento pedagógico y competencias docentes en el aprendizaje significativo en instituciones educativas públicas en Perú
Authors: Alberca Pintado Nancy Elizabeth , Concha Sánchez Eva Karina , Arraiza Alvarado José Javier , Neira Adrianzen Silvia Esperanza
Published: January 2022

El estudio tuvo  como  objetivo  comprobar  si es  que  el  acompañamiento  pedagógico y competencias docentes tienen influencia  en el aprendizaje significativo en las instituciones educativas del  distrito  de Lince. La investigación tiene un diseño no experimental, de  tipo  básico  descriptivo. La población estuvo conformada por 101 docentes de secundaria, pertenecientes a instituciones educativas públicas  de  Lince, la muestra fue censal. Se utilizó la técnica de la encuesta para recolectar la información, utilizando tres fichas técnicas referentes a la evaluación de acompañamiento pedagógico, evaluación de competencias docentes y evaluación aprendizajes significativos con 18,16 y 19 ítems respectivamente, cada cuestionario tuvo una duración aproximada de 30 minutos. Según los resultados obtenidos para el índice de Nagelkerke se obtuvo 0,152 y una significancia de 0,002. Por lo que se concluye que el aprendizaje significativo en las instituciones educativas del distrito de Lince, se ve influido positivamente por las competencias docentes y el acompañamiento pedagógico.
Pengaruh Tata Kelola Perusahaan, Pertimbangan Etis, Pengambilan Keputusan Terhadap Pencegahan Kecurangan Dengan Sistem Pengendalian Internal
Authors: Fery Irlan
Published: January 2022

Tujuan utama penelitian ini adalah mengetahui pengaruh tata kelola perusahaan, pertimbangan etis, dan pengambilan keputusan terhadap pencegahan kecurangan dengan sistem pengendalian internal sebagai variabel moderasi untuk mengetahui berapa besar peran sistem pengendalian internal perusahaan agar kecurangan dapat diatasi. Data akuntansi dapat dijadikan sebagai alat untuk mengambil keputusan yang tepat dan cepat. Alat uji yang digunakan adalah regresi linier berganda, kemudian metode yang digunakan adalah metode deskriptif dan verifikasi. Penelitian dilakukan untuk mengetahui nilai masing-masing variabel, baik satu variabel atau lebih yang bersifat independen untuk mendapatkan gambaran tentang variabel-variabel tersebut. Populasi penelitian ini adalah BUMN di provinsi Sumatera Selatan. Teknik pengumpulan data menggunakan kuesioner secara lansung dan via e-mail, dikumpulkan dari 45 BUMD. Sampel pada Populasi dalam penelitian ini adalah 65 unit terkait yaitu bagian IT, SDM, Penjualan, Keuangan, Gudang, pada BUMN yang ada di Sumatera Selatan. Teknik sampling yang digunakan adalah proportionate stratified random sampling. Hasil yang dicapai menunjukan bahwa sistem pengendalian internal sebagai variabel moderasi sangat penting untuk mencapai tata kelola perusahaan, pertimbangan etis, dan pengambilan keputusan terhadap pencegahan kecurangan. Keterbatasan pada penelitian ini adalah pengumpulan data tidak bisa dilakukan secara langsung dan hanya bisa melalui daring. Kontribusi hasil penelitian ini terhadap pengembangan ilmu akuntansi adalah bagaimana perusahaan mengetahui bagaimana pengaruh tata kelola perusahaan, pertimbangan etis, pengambilan Keputusan terhadap Pencegahan kecurangan dengan sistem pengendalian internal.
Perancangan Sistem Informasi Akuntansi Pengontrol Arus Kas (SIAPAK)
Authors: Ratnawati Ratnawati , Ulwiyah Patimah , Siswoyo Dea Julianti
Published: January 2022

Laporan keuangan berperan penting bagi top management untuk mengambil keputusan dalam pengembangan perusahaan. Salah satu unsur penting yang dimaksud yakni laporan tentang aliran dana kas yang masuk dan keluar yang menggambarkan kondisi keuangan perusahaan secara real. Lembaga Bimbingan Belajar Delta dari awal beroperasi hingga sekarang masih menggunakan metode input data dana yang masuk dan dana yang dikeluarkan secara konvensional dimana hal tersebut sering menyebabkan permasalahan seperti laporan arus kas yang tidak sesuai dengan realitas yang terjadi. Hal ini dikarenakan bukti transaksi yang tidak lengkap sehingga sering terjadi selisih pada jumlah dana yang tercatat dan dana yang ada di akhir periode pencatatan. Selain itu, pendataan kas dengan metode ini sering mengalami kendala di akhir periode pelaporan, karyawan harus melakukan rekap ulang data kas tersebut untuk dijadikan laporan kas kepada pimpinan. Pembangunan sistem informasi akuntansi dapat menjadi solusi bagi permasalahan tersebut. Penggunaan metode RAD (Rapid Application Development) dipilih karena keunggulan metode ini yakni dapat membantu dalam pembangunan sebuah sistem informasi dalam waktu yang relatif singkat. Tujuan pembangunan aplikasi ini adalah agar perusahaan ini dapat melakukan pengontrolan dana perusahaan baik pendapatan maupun penggunaan dana perusahaan secara efisien. Hasil dari pembangunan aplikasi ini yakni dapat meningkatkan kinerja serta kecepatan karyawan dalam melakukan pencatatan transaksi kas sehingga dinilai lebih efektif.
SEMANTIC PROFILE OF UNIVERSITYâ€™S VISION AND MISSION: A PROSPECTIVE CASE STUDY
Authors: Tawami Tatan
Published: January 2022

This paper proposes the semantics of product functions in a private university in Indonesia. The so-called product of the university is the Vision and Mission that carries intended and aligned message to its target readers/customers. Therefore, this research aims at mapping the semantic profile of Universityâ€™s Vision and Mission. Analysing this issue, qualitative-descriptive method was implemented to break-down the message of the product function. The results showed that the product clusters the message into general structure of the product, open word class clustering, and word clustering based on meaning association. The semantics then voluntarily specifies particular strategies based on its meaning association. Additionally, the findings suggested that the product function was discovered by analysing the descriptive words in the Vision and Missions. From this discovery, the product can then be mapped into its function class and type. This then specifies possible strategies implemented in â€œmarketingâ€ the product. From the result, it can be concluded that mapping out the message and strategy of the product can best aid universities in improving their language design in every product they have.
Perancangan Media Informasi Mengenai Hewan Reptil Chameleon Dalam Buku Ensiklopedia
Authors: Syakur Savira Alvina , Hidayatullah Taufan
Published: January 2022

Perancangan dari salah satu hewan reptil mulai dari bentuk dan kemampuannya, hewan reptil tersebut ialah Chameleon. Hewan ini banyak yang belum memahami mengenai bentuk juga dari karakteristiknya. Adapun yang menjadikan latar belakang dari perancangan ini karena hewan Chameleon ini memiliki daya tariknya sendiri mulai dari kemampuannya yang dapat merubah warnanya dan juga sebagai hewan peliharaan yang jinak dan juga memiliki sebuah nilai dilingkungan sosial, hewan Chameleon ini merupakan hewan impor. Chameleon merupakan hewan yang mempunyai pecintanya sendiri namun banyak juga yang menganggap bahwa Chameleon merupakan hewan yang kurang tepat untuk dipelihara. Oleh karena itu, penting untuk adanya sebuah media informasi yang didalamnya terdapat pemaparan tentang hewan Chameleon adalah hewan yang mengagumkan dan cara pemeliharaan Chameleon dengan menggunakan bahasa yang sederhana dan mudah dimengerti agar kegiatan memelihara Chameleon di masyarakat bukan lagi kegiatan yang sulit untuk dikerjakan. Solusi perancangan yang akan dibuat ialah dengan menghadirkannya sebuah media informasi mengenai hewan reptil Chameleon yaitu sebuah buku ensiklopedia yang memaparkan jelas mulai dari jenis Chameleon hingga cara memelihara Chameleon.
Keteladanan Inggit Garnasih, Sang Pemilik Simbol Kesetiaan
Authors: Trianasari Intan , Ekawardhani Yully Ambarsih
Published: January 2022

Inggit Garnasih memiliki peran besar dalam kehidupan Soekarno sebagai wanita yang  telah mendedikasikan hidupnya untuk membantu kemerdekaan bangsa ini. Sebagai wanita yang lemah lembut Inggit Garnasih mampu membentuk karakter pasangan menjadi seseorang yang berpengaruh terhadap keluarga dan bangsanya. Pada dasarnya wanita mampu membantu pembentukan karakter yang sangat berpengaruh dalam kelangsungan seorang penerus bangsa. Hal ini menjadikan peran wanita harus lebih diperhatikan khususnya sebagai contoh kaum wanita saat ini yang membutuhkan sosok teladan sebagai panutan. Dalam kisah hidupnya Inggit Garnasih mengajarkan enam poin keteladanan yang mampu memberikan contoh baik, kepada generasi muda yang membutuhkan sosok wanita teladan sebagai panutan. Keenam peran inilah yang diangkat sebagaipoin keteladanan untuk menjadi contoh ketegaran dalam kehidupan wanita saat ini. Media informasi berupa novel romansa menjadi solusi untuk menjadi bahan renungan dan inspirasi. Karya ini diharapkan mampu mendorong wanita untuk memahami dan meneladani peran Inggit Garnasih sebagai sosok teladan dan mampu menerapkan poin tersebut dalam hidup bermasyarakat saat ini.
Desain Ilustrasi Tokoh Suryaputra Karna Mahabharata
Authors: Shiddiq H Ryan Fatah Ash , Albar Deni
Published: January 2022

Nilai positif kehidupan terkandung dalam budaya dan karya sastra yang mengandung nilai kehidupan dan juga ilmu pengetahuan yang berpengaruh dalam kehidupan manusia hingga saat ini. Mahabharata merupakan salah satu dari dua karya sastra kuno yang berasal dari India, selain dari Ramayana, adapun beberapa versi dari cerita Mahabharata ini. Mahabharata menceritakan kisah konflik para Pandawa lima dengan saudara sepupu Pandawa yaitu 100 Korawa, mengenai sengketa hak pemerintahan istana Hasstinapura. Suryaputra Karna adalah salah satu kesatria yang ada di dalam cerita Mahabharata dan berperan penting terhadap jalan ceritanya. Makna kehidupan yang dapat diambil sangatlah banyak di dalam perjalanan hidup Karna, perancangan ini mendeskripsikan makna kepahlawanan yang dimiliki oleh Suryaputra Karna di dalam cerita Mahabharata. Kesimpulan yang didapatkan dari perancangan ini, menceritakan perjalanan Karna yang melalui banyak cobaan, fitnah, dan lainnya yang pada akhirnya memperlihatkan nilai tokoh yang dimiliki Karna sebagai antagonis yang dapat menjadi tokoh yang lebih baik dan menyelamatkan atau menyelesaikan masalah yang ada. Pentingnya tujuan perancangan ini bertujuan untuk melestarikan tokoh Karna dan cerita rakyat yang dapat diadaptasi menjadi media lainnya dan dapat mudah diterima oleh kalangan remaja saat ini.
PENGARUH PENGALAMAN KERJA, PELATIHAN KERJA DAN DISIPLIN KERJA TERHADAP KINERJA KARYAWAN PADA PT.VONEX INDONESIA RANCAEKEK
Authors: Hidayat Irpan Sarip , Wulantika Lita
Published: January 2022

Penelitian ini untuk mengetahui pengaruh Pengalaman Kerja, Pelatihan dan Disiplin Kerja terhadap Kinerja Karyawan pada PT. Vonex Indonesia Rancaekek baik secara parsial maupun simultan. Sampel penelitian sebanyak 34 karyawan. Penelitian ini menggunakan metode deskriptif dan verifikatif. Teknik pengujian hipotesis Uji T dan Uji F serta teknik analisis data Regresi Linier Berganda. Hasil menunjukkan Pengalaman Kerja berpengaruh terhadap kinerja karyawan, Pelatihan Kerja berpengaruh terhadap kinerja karyawan, Disiplin kerja berpengaruh terhadap kinerja karyawan. Pengalaman kerja, pelatihan kerja dan disiplin kerja terbukti berpengaruh terhadap kinerja karyawan.
PENGARUH PENGEMBANGAN KARIR, STRESS KERJA DAN LINGKUNGAN KERJA TERHADAP KINERJA KARYAWAN (STUDI KASUS PADA BAGIAN QUALITY CONTROL DI KPSBU LEMBANG KABUPATEN BANDUNG BARAT)
Authors: Ramadhan Fajar , Narimawati Umi
Published: January 2022

THE EFFECT OF CAREER DEVELOPMENT, WORK STRESS AND WORK ENVIRONMENT ON EMPLOYEE PERFORMANCE (CASE STUDY ON QUALITY CONTROL SECTION AT KPSBU LEMBANG, WEST BANDUNG REGENCY)
Dukungan Sosial dan Job Burnout Pengaruhnya Terhadap Kinerja Polisi (Studi Kasus Pada Anggota Kepolisian Polrestabes Bandung)
Authors: Rizqi Muhamad Husnul , Riyanto Agus
Published: January 2022

This research has a purpose was to determine the effect of social support and burnout on police performance at Polrestabes Bandung both descriptively and verification consisting of simultaneous and partial. There is a population of 296 members of the Bandung Police Satsabhara Polrestabes and 75 respondent were abtained using the slovin method, using multiple linier regression analysis, classical assumption test, and hypothesis testing. which were tested using SPSS 25 for window application, and police performance are descriptive analysis, it is explained that social support, job burnout, and police performance are in the good category, the results of the verification analysis prove that social support significantly & positively affects police performance, while job burnout significantly & negatively affects police performance, then social support and job burnout simultaneously affect police performance.
PENGARUH PROFITABILITAS, KEPEMILIKAN MANAJERIAL, DAN KEPEMILIKAN INSTITUSIONAL TERHADAP NILAI PERUSAHAAN
Authors: Widilestariningtyas Ony , Ahmad Ade Kurnia
Published: January 2022

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh Profitabilitas, Kepemilikan Manajerial, Kepemilikan Institusional terhadap nilai perusahaan sektor Infrastruktur, Utilitas Dan Transportasi di Bursa Efek Indonesia pada periode 2016-2020.

Penelitian ini menggunakan deskriptif dan verifikatif dengan pendekatan kuantitatif. Populasi dalam penelitian ini adalah perusahaan sektor Infrastruktur, Utilitas Dan Transportasi di Bursa Efek Indonesia pada periode 2016-2020 yang berjumlah 78 perusahaan. Dengan pengambilan seambil menggunakan purposive  sampling  didapatkan sampel  sebanyak 10  perusahaan yang mewakili dari sektor tersebut. Teknik pengumpulan data yang digunakan adalah dokumentasi dari laporan keuangan tahunan yang  dipublikasikanoleh perusahaan  di  website  resmi  Bursa Efek Indonesia yaitu www.idx.co.id. Teknik analisis yang digunakan adalah regresi linear    berganda. Hasil pada penelitian ini menunjukkan bahwa: (1) Profitabilitas  berpengaruh  positif  dan siginifikan  terhadap  Nilai  Perusahaan; (2) Kepemilikan Manajerial berpengaruh  positif  dan siginifikan  terhadap  Nilai  Perusahaan,; (3) Kepemilikan Institusional berpengaruh positif  dan tidak siginifikan  terhadap  Nilai  Perusahaan.
The Population Census: a Tool for Consolidating or Irritating Society?
Authors: Davletshina L. A. , Karmanov M. V.
Published: January 2022

The article provides a historical digression into the population census as the only tool that makes it possible to assess the current socio-economic and socio-demographic situation in a particular territory. The possible factors causing distrust and fear among the population that arise in the process of organizing and conducting this labor-intensive process are listed. Among them: legal support; methodological foundation; consciousness and responsibility of scribes; psychological attitude of respondents.
Humanitarian and Technological Revolution: Assessment of the State of Readiness for the Transition to a New Technological Layout
Authors: Zolotareva O. A. , Darda E. S. , Tikhomirova A. V.
Published: January 2022

In the context of the current heat of global hypercompetition for the future, technological and social transformations, the deployment of the digital economy, the scale of the penetration of artificial intelligence into all spheres of life, the formation of human-centered and other models of the economy, including the model of Society 5.0, One of the priority issues on the agenda is assessment of the state of readiness of the transition to a new technological order. In this context, the article defines the conceptual framework for monitoring the readiness of the transition to a new technological order. The main obstacles that impede the receipt of complete and comprehensive information about digital transformation in the economy and its effectiveness, the scale and consequences of the introduction of artificial intelligence and technologies of the sixth technological order in the economy and the social sphere are identified. The analysis of the current state of scientific and technological development for a number of indicators is presented.
Planning under Sustainable Processes
Authors: Shcheglov Yu. A.
Published: January 2022

The article presents the models used in the planning of production with unstable technology. This issue is becoming increasingly important for universities in connection with the transition of the Ministry of Science and Higher Education to the new principle of planning a state order for specialists, when the admission figures in the state assignment turn into release figures. For successful work in these conditions, universities are forced to change their system of planning for the training of specialists. The considered models are a proven tool for determining the size of the contingent and the necessary resources, which must be launched into the educational process in order to fulfill the state order by a given deadline.
Large-Scale Transport Projects: Accuracy in Cost Estimation
Authors: Pyataev M. V.
Published: January 2022

Currently, several studies have been conducted about overspending of funds in large-scale projects, including transport. International studies show that overspending by 20–100 % is not an exception, but an established fact. The article presents the results of comparing the estimated cost with the actual costs for several large-scale transport projects that were implemented on the territory of Russia. The conclusion is made about the need for a systematic analysis when evaluating the effectiveness of projects of this class.
Selection of a Higher Educational Institution by Foreign Students: Motives, Factors and Problems (Based on the Results of Sociological Studies)
Authors: Volovskaya N. M. , Plyusnina L. K.
Published: January 2022

The article presents the results of two sociological studies carried out for the purpose of research of motivation of obtaining a higher education and factors of selection of a higher educational institution by foreign students, revelation of problems and elaboration of recommendations for their solution. It was revealed that foreign students in general praise obtaining a higher education, and that motivational postulates of obtaining education include not only commercial goals but cultural as well. It was established that Russian education is praised by foreign students in terms of quality, and that foreign students seek Russian education purposefully. It was found that Russia is a financially attractive country for foreign students, including employment. The study demonstrated a great significance of the website and social media of a higher educational institute for making decision on obtaining education in this higher educational institute. The results of the study showed that the level of competence in higher educational institutes of the city conforms to the requirements of foreign students and satisfies their demands maximally. At the same time several problems were revealed relating to training of foreign students: language problems; problems in training; communicational problems; social and cultural problems and social and everyday problems. Several recommendations were made to solve those problems.
Desarrollo de competencias académicas específicas para el aprendizaje de la Anatomía Humana/ Development of specific academic skills for the learning of Human Anatomy
Authors: Castañeda Liliana , Main Gabriela , Benzi Patricia
Published: January 2022

Este proyecto tuvo como objetivo lograr una mejora en el aprendizaje de las estructuras anatómicas a través del desarrollo de competencias. Se seleccionaron dos competencias disciplinares específicas: “Analiza modelos gráficos de estructuras anatómicas para obtener información y realizar inferencias que le permitan comprender dicha estructura” e “Interpreta los cortes de las estructuras anatómicas para ampliar su comprensión espacial”. Para cada una se valoró, en cada estudiante, el nivel alcanzado en cada uno de los indicadores de logro establecidos. Esta metodología permitió hacer foco en la evaluación formativa. Se utilizaron como instrumentos de valoración las propias tareas llevadas a cabo en el proceso de aprendizaje, para una evaluación auténtica. Se confeccionaron las guías de actividades y las tablas para registro. Se aplicó durante el cursado del tema Sistema Nervioso (SN), dadas las dificultades que su comprensión presenta a los estudiantes. Los resultados obtenidos muestran que esta metodología implementada contribuyó a la mejora en el aprendizaje ya que el 78% de los estudiantes alcanzó o superó el nivel satisfactorio en todos los indicadores de las competencias buscadas, superando las dificultades detectadas.
Análise do Mercado de Oncológicos e Novas Substância Ativas para o Tratamento do Câncer / Oncology Market Analysis and New Active Substances for Cancer Treatment
Authors: Viana Douglas Carvalho Francisco , Moura José Arion da Silva , Branco-Júnior Jeann Fabiann , Ramalho Eduardo Augusto V. de Freitas , Pitta Ivan da Rocha , Pitta Marina Galdino da Rocha
Published: January 2022

O presente trabalho buscou analisar o comportamento do mercado farmacêutico de oncológicos e aspectos do planejamento de novos fármacos quimioterápicos para o tratamento do câncer aprovados pelo FDA no período 2015-2020. A análise do mercado de oncológicos demonstrou tendência de crescimento para os próximos anos e um aumento no lançamento de drogas órfãs.  Foram analisadas 50 Novas Substâncias Ativas obtidas a partir de síntese química, observando o tipo de câncer, alvo terapêutico, grupos heterocíclicos e aderência às regras de Lipinski. O principal alvo dos novos oncológicos foram as quinases (especialmente com atuação em tirosina quinases) e os principais grupos heterocíclicos foram anéis nitrogenados, com prevalência de piridinas e pirimidinas. A avaliação das regras de Lipinski demonstrou que 19 substâncias violaram ao menos uma das regras de Lipinski e três substâncias violam duas regras. A análise dos novos fármacos oncológicos demonstra a importância do desenvolvimento dos quimioterápicos e dos grupamentos heterocíclicos com a presença de nitrogênios. O estudo também oferece insumos que contribuem para o planejamento e desenvolvimento de novas moléculas que ofereçam opções seguras e eficazes para o tratamento do câncer.
Implantação do sistema Milk Run em uma empresa do polo de duas rodas em Manaus / Deployment of the Milk Run system in a two-wheel polo company in Manaus
Authors: Nogueira Shelle Pontes , De Vilhena Maílson Batista , Estumano Diego Cardoso
Published: January 2022

O presente estudo procura demostrar a importância do gerenciamento logístico para que uma empresa possa reduzir custos e ganhar competividade em meio a um mercado que se mostra cada vez mais exigente e complexo. Nesse contexto este trabalho apresenta uma proposta de implantação do sistema Milk Run para otimização a rotas, coletando peças dos fornecedores e devolvendo as embalagens vazias (logística reversa) e consequentemente a redução de estoques. Foram explorados os conceitos de logística, Just in Time, Milk Run, Kanban e finalizando com o Planejamento e Controle de Produção (PCP), tanto para reforçar a importância do gerenciamento logístico como para mostrar as obras relacionadas ao estudo. O resultado mostra que a empresa em questão implantou o sistema Milk Run por concebê-lo como um processo efetivo para disciplinar o fornecedor e, com isso, obter maior controle da cadeia de abastecimento e excelência no atendimento aos clientes e organizando o seu processo de carga e descarga, na qual a empresa é composta somente de uma doca para realizar esta operação. O estudo evidenciou que após a substituição do sistema convencional pelo sistema Milk Run, a empresa conseguiu melhorar os índices de entrega considerando os quatros fornecedores com maior volume de cargas. O estudo foi ampliado criando rotas e horários de entrega que melhor atendessem os interesses da empresa e dos fornecedores. Foi possível constatar a redução significativa de veículos envolvidos no processo de entrega de peças e materiais, uma vez que se buscou a centralização das entregas com veículos pré-definidos, mantendo-se sempre os mesmos motoristas para as mesmas rotas e fornecedores com o objetivo de aumentar o comprometimento deste processo. O Milk Run evidenciou ser um sistema que necessita do envolvimento de todas da cadeia
Características sociodemográficas e de trabalho do profissional da educação física de academia / Sociodemographic and work characteristics of the physical education professional in fitness centers
Authors: Jesus Leticia de , Fischer Frida Marina , Figueira Junior Aylton José , Tsukamoto Mariana Harumi Cruz , Andrade Douglas Roque
Published: January 2022

Como objetivos foi identificado o perfil do profissional de Educação Fisica e o estilo de vida, utilizou-se de um levantamento bibliográfico e  um questionário. Foram pesquisados 80 profissionais de Educação Física que atuam em academias da zona leste de São Paulo. A maioria dos profissionais era do sexo masculino e tinham em média de 33 anos; trabalhavam dois anos na academia onde foi realizada a pesquisa; 55% obtinham carteira e previdência social. Houve uma prevalência baixa de doenças e lesões. O pentáculo do bem-estar teve um resultado positivo para os indicadores de estilo de vida. É uma profissão recente no mercado, e um dos grandes desafios desta área é o processo de envelhecimento e o plano de carreira. Em média esses profissionais têm 2 empregos e dividem a rotina e seu tempo com outras atividades. Podemos concluir que os profissionais deste estudo são considerados jovens e fisicamente ativos, além de ter poucos problemas de saúde.
A percepção da alfabetização e do letramento científico nas ciências da natureza por alunos da educação básica, superior e professores no exercício da docência / The perception of literacy and scientific literacy in the natural sciences by students of basic and higher education and teachers in the exercise of teaching
Authors: Paniagua Cleiseano Emanuel da Silva , Soares Anelise dos Santos Mendonça , Santos Valdinei de Oliveira
Published: January 2022

As ciências da natureza têm um papel de suma importância no processo de aquisição e domínio de conceitos e definições (Alfabetização Científica - AC) e que possibilita a reflexão e compreensão do contexto em que se insere (Letramento Científico - LC). Entretanto, a BNCC estabelece habilidades e competências a serem desenvolvidas pela área de ciências da natureza, não apresentando propostas para se obter êxito e nem sugerindo formas de se utilizar AC e LC como ferramentas facilitadoras no processo de ensino-aprendizagem.  Como consequência imediata, gera-se um problema cíclico e crônico tanto na educação básica, quanto no ensino superior nos cursos de licenciaturas e pós-graduação lato sensu nas áreas de ensino de ciências.  Logo, o professor apresenta dificuldade na compreensão e distinção de AC e LC, bem como na contextualização de conhecimentos científicos. Diante disso, este trabalho proporcionará: i) uma ampla revisão dos conceitos de AC e LC apresentados por diferentes pesquisadores; ii) correlacionar a falta de sintonia entre as habilidades e competências que norteam o ensino de ciências da natureza no ensino médio presentes na BNCC; iii) apresentar diferentes trabalhos que investigaram formas de melhorar o processo de ensino-aprendizagem em biologia e química, tornando mais significativo e; iv) apresentar trabalhos que investigaram a falta de distinção e compreensão de AC e LC por parte tanto dos professores que já exercem a docência, quanto para os que se encontram em processo de formação.
Uso de medicamentos opióides em unidades de pós operatório de cirurgia cardíaca / Use of opioid medications in post cardiac surgery units
Authors: Calvis Lara Geovanna Ferreira Lara Geovanna , Barros Lizandra Alvares Félix
Published: January 2022

A analgesia no pós-operatório de cirurgia cardíaca é de extrema importância para a recuperação e evolução do paciente. Dentre os medicamentos mais utilizados no tratamento da dor aguda pós-operatória estão os fármacos opioides/opiáceos. O objetivo desse estudo é avaliar a utilização de medicamentos opioides em pacientes que foram submetidos à cirurgia cardíaca através de uma revisão integrativa de literatura. Estudo bibliográfico sistematizado, do tipo descritivo e exploratório. Foi formulado a seguinte questão norteadora: o que a literatura atual produziu quanto ao uso de opiáceos para analgesia no pós operatório de cirurgia cardíaca? Parai isso, foram realizadas buscas eletrônicas nas bibliotecas virtuais e bases de dados. Foram selecionados seis artigos de diferentes tipos de estudo. Os opioides são os fármacos mais utilizados no manejo da dor pós-operatória. A mensuração da dor através de escalas numéricas é de extrema importância a fim de alcançar os resultados esperados através da terapêutica escolhida, no entanto esta prática ainda não é pertinente. A literatura nos trás outras drogas que auxiliam nesse processo, porém, elas ainda não substituem o uso dos opioides, que por sua vez causam diversos efeitos colaterais, como depressão respiratória e sedação. Dentre a classe dos opioides, a Metadona é a mais eficaz e utilizada. Os opioides são drogas extremamente eficazes no tratamento de dor aguda, porém deve ser foco de mais estudos para reduzir seus efeitos colaterais.