bluuebunny/crossref_metadata_2025 huggingface dataset:
Cardiovascular risks in infants born with reproductive technologies
Authors: Gorlova I. A. , Omelchenko M. Ju. , Sokolova L. A. , Bondarenko B. B.
Published: December 2020

Russia is on the second place among European countries in the number of completed cycles of assisted reproductive technologies (ART). The proportion of children conceived using ART becomes annually higher. The present review summarises data on the impact of new reproductive technologies on the risk of developing cardiovascular diseases are presented. Potential health risks in the introduction of ART in babies born are discussed in numerous studies, the impact on all stages of embryo- and organogenesis is noted. The greatest problem is a possible increase in the incidence of congenital malformations (CM) in children after ART compared to the latter in the natural population. The frequency of CM is due not only to the use of APT, but also to factors such as genetic characteristics, age and state of health of the mother, aggravated obstetric-gynecological history, multiplicity, low birth weight of the fetus. In children conceived with ART, often appear early symptoms of systemic endothelial dysfunction, metabolic disorders (lipid metabolism, glucose level), congenital heart defects (interventricular septum defect, small cardiac development abnormality (false chord), open arterial duct, open oval window). There is a need to improve prenatal diagnostics of CM in early pregnancy and regular medical examinations of children conceived with ART.
Pharmacoresistant temporal epilepsy: the relationship of epileptiform activity and structural changes in the hippocampus
Authors: Cherenkova S. E. , Marchenko E. V. , Alexandrov A. M. , Arkhipova N. V. , Chukhlovin A. A. , Sebelev K. I. , Alexandrov A. M.
Published: December 2020

Background. Hippocampal sclerosis is one of the most common structural lesions associated with epilepsy. The standard medical care in the treatment of drug-resistant temporal lobe epilepsy associated with hippocampal sclerosis is surgery with anterior temporal lobectomy. The extent of resection depends on the involvement of hippocampal sclerosis in the epileptic system. Objective. Determine the relationship between the involvement of the hippocampus in the epileptic system (on the basis of the results of intraoperative electrocorticography (ECoG)) and the presence of structural changes in it, found on the basis of MRI data. Materials and methods. The present article presents an original retrospective study of the dependence of the signs of hippocampal sclerosis according to neuroimaging data and the formation of epileptiform activity in 36 patients treated at the Polenov Neurosurgical Institute — branch of Almazov National Medical Research Centre in 2015–2018. Results. Depending on the presence of hippocampal sclerosis and epileptiform activity, patients were divided into 4 groups: 1) patients with the presence of both hippocampal sclerosis and epileptiform activity in the mesiobasal structures (n = 15); 2) patients with identified sclerosis of the hippocampus, without registration of specific activity according to the results of ECoG (n = 8); 3) patients with epileptiform activity, while MR-negative (n = 10); 4) patients without epileptiform activity and without signs of hippocampal sclerosis according to MRI (n = 3). After a statistical check of the distribution of patients, it was found that the distribution was random. Conclusion. The fact of the presence of structural changes in the hippocampus could not be a pathognomonic sign of the inclusion of the hippocampal-entorial complex in the epileptic system.
Possibilities for correcting hepatotoxic reactions during therapy in patients with COVID-19 (case report)
Authors: Smok A. M. , Malkova A. M. , Kudlay D. A. , Starshinova A. A.
Published: December 2020

In 2020, a pandemic of the new coronavirus infection (COVID-19) began. Treatment of this infection is limited by the lack of effective etiological treatment, which requires the selection of empirical and symptomatic therapy. The obtained some effectiveness of the use of antimalarial drugs, antiretroviral drugs in combination with antibacterial therapy made it possible to recommend it for use in the treatment regimen for patients with COVID-19. However, these drugs provoke the development of undesirable side reactions that require correction to continue treatment. Considering the need to use complex therapy in the treatment of patients with COVID-19 and the direct effect of the virus on liver cells, the likelihood of developing hepatotoxicity is quite high. The described cases of liver damage are characterized by impaired functional activity, an increase in the level of liver function tests, the development of small-drop fatty infiltration and a mild inflammatory reaction in the liver lobules. The development of these complications requires the hepatoprotective drugs, which increase the liver’s resistance to the damaging effects of various pathogens and help restore the functional activity of hepatocytes. According to the conducted studies, hepatotropic drug inosine+ + meglumine + methionine + nicotinamide + succinic acid and reamberin contribute to the normalization of lipid metabolism, a decrease in the level of enzyme markers of liver damage. The article presents the complex treatment with lopinavir + ritonavir. Thanks to hepatoprotective therapy, a week later, a decrease in ALT, alpha-amylase, blood counts to normal values was achieved.
Nursing Care of a Patient Diagnosed with COVID-19: A Case Report According to Meleis' s Transition Theory
Authors: ÖZYER Yasemin , YANMIŞ Safiye
Published: December 2020

The transition theory developed by Afaf İbrahim Meleis is a nursing theory aimed at defining changes in individuals’ lives and improving their health. Effects of such changes and transitions on individuals’ health differ from one person to another. Nurses assist patients in these transition times by developing different intervention methods for them. Meleis' s transition theory is of importance because it is based on nursing profession and has contributed to the emergence of nursing science. A female patient presented to a private health institution with complaints of fever (38.2°C) and sore throat. The result of the 2019-nCov test performed was positive and she was quarantined in a socially isolated room of the hospital. Uncertainty and fear of death due to COVID-19, a global epidemic, bring about serious consequences for patients. In this case report, in line with Meleis’ s transition theory, nursing care was planned for this 52-year-old woman diagnosed with 2019-nCov.
Classification of Prostate Cancer and Determination of Related Factors with Different Artificial Neural Network
Authors: BALIKÇI ÇİÇEK İpek , KÜÇÜKAKÇALI Zeynep
Published: December 2020

Objective: In this study, it is aimed to classify prostate cancer, compare the predictions of these two models and determine the factors associated with the disease by applying Multilayer Perceptron Neural Network (MLPNN) and Radial-Based Function Neural Network (RBFNN) methods on the open access Prostate cancer dataset.Methods: In this study, the dataset named "Prostate Cancer Data Set" was used by obtaining from https://www.kaggle.com/sajidsaifi/prostate-cancer address. To classify prostate cancer, MLPNN and RBFNN methods, which are artificial neural network models, is used. The classification performance of the models was evaluated with the sensitivity, specificity, accuracy, negative predictive value and positive predictive value, which are among the classification performance metrics. Prostate cancer related factors were estimated by using MLPNN and RBFNN models.Results: With the applied MLPNN model, performance metric values were obtained as AUC 0.937, Sensitivity 100%, accuracy 92.5%, Selectivity 84.6%, Positive predictive value 87.5% and Negative predictive value 100%. With the RBFNN model, the performance metric values were obtained as AUC 0.921, Sensitivity 83.3%, accuracy 86.6%, Selectivity 91.6%, Positive predictive value 93.7% and Negative predictive value 78.5%. When the effects of variables in the dataset in this study on prostate cancer are examined; The three most important variables for the MLPNN model were obtained as perimeter, area and compactness, respectively. For the RBFNN model, the three most important variables were obtained as perimeter, area and compactness, respectively.Conclusion: It was seen that MLPNN and RBFNN models used in this study gave successful predictions in the classification of prostate cancer. In addition, estimating the significance values of factors associated with the disease with these classification models made it different from similar studies with the same dataset.
Student Opinions on the Importance and Detail of the Accumulation of Anatomy Knowledge Integrating General Surgery
Authors: BODUÇ Erengül , ALLAHVERDİ Tülay
Published: December 2020

Objective: The aim of the study is to create an original study that guides the anatomy and surgical branches and supports education within the framework of their opinions by raising awareness on this issue in medical faculty students.Methods: The study was carried out on the fourth, fifth and sixth year medical students of Kafkas University Medicine Faculty in the 2019–2020 academic year. Data collection questions were prepared with a five-point Likert scale. The answers given by the students were automatically analyzed through the web system and the results were obtained through the softwareResults: The participation of the students to the opinions of the questions 1, 2, 4, 8, 10 and 12 is quite high (73.2%, 74.6%, 56.3%, 67.6%, 52.1%, 62%). In general, the students want the integration of anatomy into clinical branches in a more up-to-date manner, apart from the traditional anatomy course.Conclusion: This study was conducted for the importance and awareness of the integration of clinical and anatomy branches with each other. Student opinions were taken to emphasize the importance of the study. Anatomy basis is very important for surgical branches. Apart from classical anatomy education, anatomy education should keep up with technological developments and should be more integrated with clinical branches.
Radiologic analysis of correlations between sinonasal anatomical variations in patients with nasal septal deviation
Authors: KARALI Elif , GÜNEŞ Akif , DAĞISTAN Emine , COŞGUN Zeliha , URAL Ahmet , KALAYCIOĞLU Oya
Published: December 2020

Objective: This study aims to analyze the sinonasal anatomical variations accompanying the nasal septal deviation, the correlations between these variations, and their relationship with the septal deviation angle.Methods: In this retrospective study, preoperative paranasal computed tomography (CT) scans of 206 patients who underwent septoplasty between January 2015 and December 2019 were examined. In CT scans, different nasal septal deviation types, Keros classification, optic nerve type, ethmoid air cell variants, nasal concha variants, paranasal sinus pneumatization variants, and the correlation between accessory pneumatization variants and their relationship with the septal deviation angle were analyzed.Results: In patients with nasal septal deviation, supraorbital ethmoid cell, anterior clinoid process pneumatization and onodi cell were more frequent compared to the literature. Any significant correlation between the nasal septal deviation angle and the presence of sinonasal variants was not detected (p > 0.05). Correlations were significant between the presence of Frontal sinus hypoplasia and Haller cell (ϕ = -0.142, p = 0.042), Supraorbital Ethmoid cell (ϕ = -0.173, p = 0.013) and Paradoxal middle concha (ϕ = 0.152, p = 0.029).Conclusion: Careful examination of paranasal CTs before craniomaxillofacial surgeries is important to determine sinonasal anatomic variants, to determine the appropriate treatment plan and to prevent possible complications peroperatively.
Sialolith of The Submandibular Gland: A Case Report
Authors: AYRANCI Ferhat , ÖMEZLİ Mehmet Melih , TORUL Damla , SUNAR Çağla , KOÇ Leyla
Published: December 2020

Sialolithiasis is described as the existence of calcified structures in ducts of salivary glands and is the most widespread disease of the salivary glands. 80-95 % of sialoliths occur at the submandibular salivary gland. Sialoliths with an average frequency of occurrence of 12: 1000 are approximately twice as common in men as in women. Sialoliths may be diagnosed with clinical examination, conventional radiography, computed tomography and ultrasonography. Common clinical signs in cases of sialoliths include painless swelling, large swelling often accompanied by trismus associated with eating, symptoms ranging from moderate discomfort to severe pain. In this case report clinical, radiological signs and surgical therapy of salivary stone in the submandibular gland is represented.
INFLUENCE OF SPELEOCLIMATOTHERAPY ON THE PSYCHO-EMOTIONAL STATE, GENETIC STABILITY AND ACTIVITY OF а-AMYLASE IN THE ORAL CAVITY OF THE STUDENTS
Authors: Nechaeva M. S , Tyunina O. I. , Dorokhov E. V. , Aralova A. Yu , Potapova Yu. O
Published: December 2020

The goal of investigation was to evaluate the effect of speleoclimate on the psycho-emotional state, the frequency of occurrence of buccal epithelial cells with core aberrations and the level of а-amylase activity in the oral cavity of students. Second-year students of VSMU named N. N. Burdenko were selected as subjects. The collection of psychological parameters, buccal epithelium, to assess genetic stability, and oral fluid, for evaluation of the activity of а-amylase was carried out in the first, fourth, eighth, eleventh day visit speleochamber and four days after a course of speleoclimate. The psycho-emotional state of the subjects was assessed using the SAN questionnaire and the scale of C.D. Spielberger and Y.L. Khanin. The state of genetic homeostasis of students was evaluated using a micronucleus test in the buccal epithelium. The level of activity of а-amylase was carried out by the method of solid-phase enzyme immunoassay. Comparison of the studied indicators was carried out using the nonparametric Van-der-Warden criterion. The relationship between the dynamics of а-amylase activity and cytological parameters was revealed using the Spearman correlation coefficient (rs). The results obtained indicate a positive effect of speleoclimate on the psychological and genetic stability of a person. Subjects with low а-amylase activity showed a higher level of cells with abnormal nuclei. A negative correlation was found between the dynamics of the frequency of abnormal nuclei in buccal epithelial cells and the activity of а-amylase in the group with initially low activity (rs= - 0,8; P < 0,05). Speleoclimatotherapy can be recommended as a method of non-medicamental correction of the effects of stress influence on health of students.
RESULTS OF SURGICAL TREATMENT OF STRICTURAL DISEASE OF THE URETHRA (ACCORDING TO THE MATERIALS OF THE CLINIC)
Authors: Polyantsev A. A , Kuznetsov A. A. , Goncharov N. A , Kiseleva A. A , Morozov E. A
Published: December 2020

The retrospective analysis of results of urethral strictural disease surgical treatment cases (according to the materials of the urological department of the «Volgograd Regional Clinical Hospital № 1» for 2015-2020) was provided. The research included 168 surgical treatment cases of urethral strictures of different localization, longitude and etiology. The patients were operated using different surgical technics. Comparative analysis of results of surgical treatment in patients with urethral strictures was provided. The research evaluates the efficacy of used methods: internal optical urethrotomy, anastomotic plastics «edge to edge», buccal urethroplastics, urethral plastics without spongious body incisoin. It was found out that now-a-days the most prognostically favourable methods in urethral stictural disease surgical treatment are the buccal plastics and «edge to edge». Otherwise, due to few observed cases, the plastics without spongious body incision demands more detailed and thorough analysis for verifying it's comparative efficacy.
ANALYSIS OF THE RANGE OF NASAL DRUGS ALLOWED FOR MEDICAL USE IN RUSSIA
Authors: Sergeev N. S , Gubrieva N. A , Sergeeva A. V , Sampiev A. M.
Published: December 2020

The analysis of the assortment of nasal drugs permitted for use on the territory of the Russian Federation was carried out. The relevance of the development and introduction of systemic nasal medicines into domestic medical practice, including on the basis of fundamentally new pharmacologically active substances, has been revealed. It also shows the feasibility of conducting research in the field of creating domestic nasal medicines for pediatrics, studying the possibility of using new dosage forms for nasal medicines that meet all modern efficacy and safety requirements for high demand in the domestic and foreign pharmaceutical markets.
HEMOPOESIS AND FUNCTIONAL CONDITION OF BLOOD LEUKOCYTES DURING INFLAMMATION IN THE BACKGROUND OF LOCAL REMOVAL OF NONPHOCOTATING GRANULOZITES
Authors: Sirak A. G , Piskareva E. I , Dolgashova M. A , Magomedova O. G , Arutyunova A. P , Lyubanskaya O. V. , Nemenuschaya E. G , Didenko M. O , Kochkarova Z. M
Published: December 2020

The article is devoted to the functional state of blood leukocytes and peculiarities of hematopoiesis during inflammation under experimental conditions against the background of local removal of non-phagocytic granulocytes. The functional status of blood leukocytes obtained from 24 Wistar male rats weighing 180-220 g was judged by the activity of their marker enzymes. Myeloperoxidase (MPO) and acid phosphatase (CF), macrophage monocytes - а-naphthylacetate esterase (а-NAE), lymphocytes - CF and а-NAE served as markers of the functional activity of neutrophils. Found that during inflammation on the background of prior removal of NG from the focus, there is less neutrophil and monocyte entry from the bone marrow into the blood and further into the inflammation focus, changes in the intensity and dynamics of hemopoiesis, and as a result, increased lymphocyte degranulation.
CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND COMORBIDITY
Authors: Uryasyev O. M , Panfilov Y. A , Granatkin M. A , Pyko A. A
Published: December 2020

The article discusses comorbid diseases that occur in chronic obstructive pulmonary disease, which are considered in the context of «comorbid pathology». The pathogenesis of associated diseases and its relationship with the underlying disease is shown.
THROMBOSIS IN CHILDREN (CLINICAL CASES)
Authors: Otto N. Yu. , Sagitova G. R , Ledyaev M. Ya. , Garyanin R. V. , Ishchenko E. M , Shtepo M. V. , Shouldis V. A
Published: December 2020

We have to state that «adult» diseases are increasingly common in children. In the article, the team of authors describes the clinical cases of thrombosis in children: the difficulties of verifying the diagnosis, justifying the therapy, and the tactics of the doctor's action.
UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA AND PHYSICAL DEVELOPMENT OF CHILDREN RESIDING IN THE NORTHERN REGION OF RUSSIA
Authors: Ragozin O. N , Shevnin I. A , Ilyushchenko N. A , Ragozina O. V.
Published: December 2020

The article presents the results of assessing the physical development of children 7-17 years old in the northern region with undifferentiated connective tissue dysplasia. It has been established that undifferentiated connective dysplasia affects the degree of harmony of physical development and the formation of pathological types of posture depending on gender and age, but does not affect gender and age differences in the rates of physical development.
APPLYING THE ROBSON CLASSIFICATION TO FIND WAYS TO REDUCE THE FREQUENCY OF CESAREAN SECTION OPERATIONS
Authors: Tkachenko L. V , Verovsky T. A , Kostenko T. I , Skladanowsky T. V. , Sviridova N. I , Babayeva L. K
Published: December 2020

The outcomes of pregnancy and childbirth, which ended with a cesarean section, were studied in accordance with Robson's classification in order to find ways to reduce the frequency of surgical delivery in a level 3 hospital. The mechanisms to reduce the frequency of cesarean section in an obstetric hospital are defined: pregravid preparation in risk groups for preterm delivery and assessment of perinatal risk factors, a personalized approach to methods of pre-induction of parturition in high-risk patients, especially in full-term pregnancy, rational management of parturition, prevention of the first cesarean section, an increase in delivery through the natural birth canal in pregnant women with a scar on the uterus.
ALGORITHM FOR THE EMERGENCY BEAM DIAGNOSTICS OF A STROKE UNDER CONDITIONS OF A MODERN HOSPITAL
Authors: Zmeeva E. V. , Zmeev S. A , Lyutaya E. D
Published: December 2020

The relevance of the problem of recent diagnosis of stroke has not been reduced last years. The algorithm of using radiological methods for diagnosis acute stroke is developed, but it varies depending on the technical capacities of the specialized agencies. When a patient enters a specialized hospital, a native CT scan of the brain is performed, according of its results is made a decision to perform CT angiography of the arteries of the neck and head, MR studies of the brain, CT or MR perfusion. A team of specialists works in the emergency module, which includes a neurologist in the emergency room, a radiologist in the CT room, a radiolosergion who performs a joint analysis of the results of radiation methods and decide on further treatment tactics, which leads to a significant reduction in time from the moment the patient enters the emergency room to moment of obtaining the necessary medical care. Optimization of the interaction of specialists is carried out by creating a joint chat in the WhatsApp messenger.
HOW TO AVOID MEDICAL ERRORS IN SURGERY?
Authors: Gol'brah V. A , Maskin S. S , Matyukhin V. V
Published: December 2020

The enchantment of numbers of surgical interventions and the widespread adoption of modern technologies, lead to a parallel increase in technological errors and morbidity in recent years. This article analyzes such section of surgery as «medical errors», provides a modern classification of medical errors and complications according to foreign and Russian authors. The article contains information about definition, legal foundations and principles for the prevention of unexpected consequences of surgical interventions.
ASSESSMENT OF THE PHYSICAL DEVELOPMENT OF SCHOOLCHILDREN AGED 7-8 LIVING IN ALTAI REPUBLIC
Authors: Bauer P. S , Borodina G. N , Trebushinina T. G , Fedina I. Yu. , Subbotin E. A
Published: December 2020

The article presents the results of a survey of schoolchildren aged 7-8 living in the Altai Republic. Anthropometric studies of pupils in general secondary schools have been conducted and their level of physical development has been determined using the index method. The study found that the children of this age group have a low level of physical development and their type of build is defined as asthenic, more pronounced among girls. There's also a body mass deficit. Lack of physical development can be related to climatic characteristics, nutritional patterns and lifestyles.
ANALYSIS OF FOUR-YEAR MANAGEMENT OF PATIENTS WITH VARICOSE BLEEDING IN THE WAITING LIST FOR LIVER TRANSPLANTATION IN ROSTOV REGION
Authors: Korobka V. L , Pak E. S , Kostrykin M. Yu , Tkachev A. V , Balin N. I , Shapovalov A. M , Babieva A. M
Published: December 2020

Varicose bleeding is one of the most frequent and severe clinical manifestations of liver cirrhosis. The aim of this study was analyze of the clinical outcome of patients with varicose bleeding in the waiting list for liver transplantation (WL LT). Clinical, laboratory and instrumental data of 134 patients from WL LT were analyzed. Patients were distributed to 4 groups according to clinical outcome in WL LT: delisting, follow-up, death, orthotopic liver transplantation (OLP). Endoscopic ligation was performed in 21 patients (follow-up period from 0 to 33 months in WL LT), TlPs - 7 patients (follow-up period from 2 to 36 months.), azygoportal separation - 18 patients (follow-up period from 4 to 48 months in WL LT). The development of criteria for the priority and timeliness of measures to prevent varicose bleeding is a prerequisite for reducing mortality in the WL LT.
NFLUENCE OF THE PRODUCT AFOBAZOLE ON SEXUAL BEHAVIOR AND FERTILITY OF RATS-FEMALES
Authors: Kuzubova E. A , Bugaeva L. I , Lavrova E. B , Maltsev M. V. , Petrov V. I , Avilova T. M , Shherbakova N. M , Kharlamov I. V.
Published: December 2020

In experiments on female rats, the effect of afobazole at doses of 5 mg/kg (group 1) and 100 mg/kg (group 2) on sexual behavior and fertility was studied. It was found that in the structure of sexual behavior in rats of females treated with afobazole with a 2-week course, the duration of sexual activity and the number of lordoses decreased statistically insignificantly and dose-dependently (by 12,5 and 37,5 %, respectively), with a simultaneous tendency to increase the number emotional approaches. In addition, according to the results of fertility studies in female rats, an increase in the pregnancy index by 14,6 % (p > 0,05) was noted in both study groups, and in pregnant women, an increase in fertility, respectively, by 33,7 % (p < 0,05) and 20,4 % (p < 0,05) and a dose-dependent decrease in the total (pre- and post-implantation) fetal death by 26,4 % (p > 0,05) and 54,5 % (p < 0,05). Based on the studies, it was concluded that afobazole had a positive effect on 2-weekly administration to rats of females at doses of 5 mg/kg and 100 mg/kg on fertility processes, with a slight tendency of its deprimative effect on sexual activity.
CURRENT VIEWS ON THE PATHOGENESIS AND TREATMENT OF OVERACTIVE BLADDER
Authors: Poroyskiy S. V. , Shchelkov S. V. , Doronin A. B
Published: December 2020

Neurogenic bladder is one of the serious pathologies that strongly affect the quality of life and, sometimes, posing a threat to life. The clinical picture of neurogenic bladder presents various symptoms and severity. Depending on the etiology and pathogenesis of the disease, there are various approaches to the treatment of neurogenic bladder. Idiopathic overactive bladder has no pathogenetic treatment, because the pathogenesis of this disease is not studied. The methods of treatment are divided into drug and non-drug. Until the end, the effect on the detrusor state of drug instillations and physical methods of exposure remains unexplored.
EXPERIENCE WITH THE USE OF ORGAN-PRESERVING SURGERY ON THE ADRENAL GLANDS
Authors: Lisitcyn A. A , Zemlyanoi V. P , Velikanova L. I , Nakhumov M. M , Shafigullina Z. R
Published: December 2020

Laparoscopic adrenalectomy is the «gold standard» in adrenal neoplasm surgery. However, in the case of bilateral lesions or lesions of the only adrenal gland, it leads to the need for lifelong hormone replacement therapy. Thus, organ-preserving operations are becoming more and more in demand today. The article presents the results of laparoscopic and laparotomic resection of the adrenal gland in 32 patients with various benign adrenal neoplasms. The possibilities of organ-preserving operations on the adrenal gland were determined. Reflected approaches in the choice of partial resection of the adrenal gland.
ASSESSMENT OF THE QUALITY OF LIFE OF PATIENTS AFTER CHOLECYSTECTOMY, DEPENDING ON THE TYPE OF SURGICAL ACCESS AND THE NATURE OF THE DISEASE
Authors: Sobolev Yu. A , Belyaeva A. I , Davydkin V. I , Fedulov R. I
Published: December 2020

The prevalence of cholelithiasis among the working population ranges from 10 to 20 %. Cholecystectomy ranks first in frequency among surgical interventions. The purpose of this work is to assess the quality of life in patients with cholelithiasis 6 month after cholecystectomy. The study was conducted on the basis of three medical institutions in the Russian Federation. The patient groups were homogeneous in their composition, and the quality of life was assessed using the Gallstone Impact Checklist. The groups were compared depending on the type of operative access (laparoscopic, mini-access), and depending on the nature of the disease (symptomatic and asymptomatic variants). The results were calculated as the average calculated value ± standard deviation. The following results were obtained, which show that cholecystectomy significantly reduces the quality of life of patients. Laparoscopic access is more preferable in the presence of pain syndrome, as the main factor in reducing the quality of life. Mini-access surgery is not accompanied by a deterioration in the quality of life in patients with pain and dyspeptic syndromes, but it improves the emotional and volitional sphere of human activity.
IMMUNOLOGICAL BLOOD ANALYSIS AS A DIAGNOSTIC FACTOR OF PSYCHOEMOTIONAL STRESS AT A DENTAL APPOINTMENT
Authors: Mikhalchenko D. V. , Makedonova Yu. A , Afanasyeva O. Yu.
Published: December 2020

With the development in dentistry of dental implants is growing steadily and the number postprostatectomy complications, manifested periimplantation mucositis and dental periimplantitis. If the phenomena of mucositis are reversible, then the destruction of bone tissue around the dental implant is impossible to restore the integrity of the bone. An important diagnostic criterion is early diagnosis by a dentist of initial changes in periimplant tissue of inflammatory origin. Stress is a factor in the development of postprotetic complications. In this paper, based on the immunological parameters of blood, the factors responsible for the development of a stress-triggering reaction are determined. Based on the General and biochemical blood analysis, indicators were determined that allow assessing the stress situation in the study groups (cortisol concentration, alkaline phosphatase, Garkavi index, epinephrine, noradrenaline) in patients with postprotetic complications in the near and long-term follow-up and treatment. Proven change of immunological indices on the background of psychoemotional stress in patients with postprostatectomy complications.
SOMATOTYPOLOGICAL CHARACTERISTICS OF STUDENTS OF DIFFERENT HEALTH GROUPS BY R.N. DOROKHOV AND V.G. PETRUKHIN METHOD
Authors: Tkachenko Yu. A , Fedorov S. V.
Published: December 2020

A total of 381 girls aged 17-20 years of different health groups were evaluated. Dimensional and proportional variations of the physical parameters, body component composition were analyzed by R.N. Dorokhov and V.G. Petrukhin method. Was found that the overwhelming number of women belong to the microsomal (dimensional variation), to the microcorpulent (fat component composition), to the micro-bone (bone component composition), to the micro-muscle (muscle component composition) somatic types in all three groups. According to the proportional variation of the physical parameters, a heterogeneous distribution pattern was observed.
CRYSTALLOGRAPHIC ANALYSIS OF ORAL FLUID IN PATIENTS WITH POST-PROSTHETIC COMPLICATIONS DURING DENTAL IMPLANTATION IN THE COURSE OF TREATMENT
Authors: Mikhalchenko D. V. , Makedonova Yu. A , Gavrikova L. M.
Published: December 2020

The wedge-shaped dehydration method was used to assess the state of the oral fluid of patients with post-prosthetic complications during dental implantation against the background of various treatment methods. Oral fluid (saliva) was used as a material for the study. All patients were randomized into 4 equal groups in a 1: 1: 1: 1 ratio according to the methods of pharmacotherapy. Group I - 30 patients who underwent traditional treatment of post-prosthetic complications; Group II -30 patients, ozone therapy was performed in addition to traditional therapy; Group III - 30 people who underwent transcranial electrical stimulation against the background of traditional therapy; Group IV - treatment of 30 people with the inclusion of a combination of ozone therapy and transcranial electrical stimulation in the treatment regimen. The control group consisted of healthy individuals of the same age group. Determined the nature of the organization of the structure of the salt and the distribution of the protein substance, depending on the concentration of protein in the biological fluid (saliva). Qualitative analysis of images of saliva crystallograms was carried out in the next (before treatment, 3 days, 7 days, and 14 days) observation and therapy. As the duration of treatment increased, the structuring of the crystal lattice took place, increasing in the series: patients with traditional therapy - patients with ozone therapy - patients with transcranial electrical stimulation - patients with combined use of ozone and transcranial electrical stimulation (group IV). Special attention should be paid to the fact that the complete normalization of the structure of the oral fluid facies occurred only during the complex therapy with ozone and TPP throughout the study.
Involvement of Moscow medical personnel in the mentoring system
Authors: Kolennikova Olga
Published: December 2020

The article is devoted to the study of real and prospective practice of mentoring. The information base was data from the questionnaire survey of the personnel of Moscow medical organizations, carried out in 2019. The scale and character of the involvement of medical personnel in the mentoring system were studied with regards to prospective and appropriate models. The need for introduction or expansion of mentoring was compared with the available personnel potential. It turned out that doctors and nurses are involved in various types of mentoring. These are additional training in the workplace, regulated by the management, initiative assistance to youth during their adaptation, and various forms of informal transfer of practical knowledge on a wide range of issues. The demand for mentoring turned out to be higher among doctors and in hospitals. A comparison of respondents who had a mentor and who did not had one, but needed, revealed a shortage of models beyond the standard adaptation. Three groups of respondents were compared: those who were already a mentor, who would agree to become a mentor, who did not want to become a mentor. The educational and qualification level, research activities, work experience in the specialty, specifics of providing medical care with the account of complexity and responsibility were the comparison criteria. The need to introduce or expand mentoring is recognized by many respondents, and the potential composition of mentors allows us to speak about the prospects for its development.
Educational capital as a basis for formation of labor strategies
Authors: Yarasheva Aziza
Published: December 2020

On the basis of general scientific dialectical approaches, the article examines the issues of formation and development of educational capital as an integral part of human capital. The purpose of the article is to identify the features of the impact of the quality and level of education on the possibility of building labor strategies using the example of employees in healthcare as, as a specific industry in terms of building career trajectories. The features characteristic for formation of the educational capital of medical workers are highlighted. Based on the study of opinions (sociological surveys) of doctors and nurses at metropolitan healthcare organizations, conclusions were drawn: about availability and necessity for them to receive additional education, about the factors affecting the level of professionalism in performing work duties, about the most relevant types of training programs within the framework of continuing medical education, about the career types characteristic of medical personnel. It is shown that healthcare workers who successfully implement their professional labor strategy, as a rule, not only make optimal use of their existing educational capital, but also constantly improve their qualifications on the basis of continuous medical education. There are identified: categories of workers who are most in need of additional training; current directions of educational programs for heads of medical institutions; features of educational and professional trajectories connected with higher nursing education; differences in the opinions of doctors and nurses regarding the necessity and importance of self-education in the process of forming (replenishing) their educational potential. Rapid development of innovative technologies in medicine, which entails the need for advanced training of specialists, requires search for new effective forms of training for healthcare workers.
Transformation of processes of external labor migration during the spread of the COVID-19 infection
Authors: Krasinets Evgeny , Gerasimova Irina
Published: December 2020

The article deals with the impact of external labor migration on the balance of the labor market in the Russian Federation. The main emphasis is placed on the need to monitor the migration situation and taking timely "migration" measures by the Government of the Russian Federation based on its results. The migration component is presented in strategic planning documents and correlated with the socio-economic development of the Russian Federation. At this moment, against the background of the current unfavorable epidemiological situation caused by the spread of a new coronavirus infection (COVID-19), the Government of the Russian Federation is taking a number of measures to prevent the spread of COVID-19, including those in the field of migration. The article analyzes the current measures preventing departure of labor migrants staying in the Russian Federation and other categories of foreign citizens who have arrived for the purposes other than work in the "shadow sector" of the labor market. It shows the present state of external labor migration by analyzing statistical and informational data, as well as possible risks in the implementation of social and labor relations. Sectors of the economy have been identified that may experience a shortage of labor resources as a result of the implementation of measures to prevent the spread of coronavirus infection. Dependence of the sphere of external labor migration on macroeconomic, international and political factors is stated. Particular attention in the article is paid to the institute of highly qualified specialists (HQS). The need was expressed to improve the procedure for attracting foreign citizens to work on the territory of the Russian Federation as HQS, to set additional criteria for their selection, to introduce an advance payment of income tax on HQS and to increase employers' liability for violation of the established procedure in this area, including the need to diversify control mechanisms for employers who attract foreign citizens as highly qualified specialists.
III Rimashevskaya Readings: Saving Russian Population: Health, Employment, Standards and Quality of Life
Authors: Dobrokhleb Valentina
Published: December 2020

III Rimashevskaya Readings: Saving Russian Population: Health, Employment, Standards and Quality of Life
Minimum size of wage and its differentiation
Authors: Toksanbaeva Mairash
Published: December 2020

Raising minimum wage can lead to such a contraction in its differentiation that weakens the stimulating function. The article raises the question of the influence on this function of the minimum wage growth to the level of the subsistence minimum of an able-bodied person. According to Rosstat information, the decrease in the differences in earnings of workers depending on their qualifications began in 2017 and continued in 2019. The R/P10% ratio also declined but was still too high. The study of the causes of this phenomenon is based on the hypothesis that, first of all, it is rooted in the earnings differentiation by type of economic activity (industry). For the analysis, industries were selected in which the key professional groups consist of the most qualified personnel, namely highly qualified specialists and skilled workers. Contraction of inter-qualification differentiation below the reasonable standards took place in industries with wages not higher than the average for all employees. This process began in 2017, when the minimum wage had not yet reached the subsistence level. In key occupational groups in some high-wage industries the differences under consideration reached excessively high values. And in industries with low wages, the differentiation by key groups slightly increased in comparison with 2017. This can be explained by weakening of labor incentives and an attempt to restore them after this weakening. This confirms that ensuring of the reproductive function of payment for labor should be consistent with the effectiveness of the stimulating function. However, without reducing the differences in earnings by industry, achieving such consistency is not possible.
Human and scientific-technical potential: regional correlation analysis
Authors: Fedotov Artem
Published: December 2020

The development of scientific and technical potential in the regions of Russia is an important task, without which it is difficult to imagine the competitiveness of the domestic economy. On the other hand, innovative development is closely related to such a social category as the human potential of the population. The article presents the results of a correlation analysis between indicators of scientific and technical potential, reflecting the resource component and the results of innovative activity of regions, on the one hand, and indicators of human potential, in particular, its physical aspect, on the other. The results obtained confirmed the absolute positive correlation between the indicators of scientific and technical potential and positive factors of human potential (life expectancy, natural population growth, the spread of education, visits to museums and theaters), as well as a negative relationship with negative factors of human potential (the level of addiction). The factors of scientific and technical potential that are most sensitive to the values of human potential indicators are revealed: internal costs for research and development, internal costs for technological innovation, the number of advanced production technologies used. A more detailed correlation analysis was carried out with the study of time lags separately for each region between the indicators of scientific and technical potential and three indicators of the physical aspect of human potential: life expectancy, natural population growth, the spread of alcoholism and drug addiction. The results obtained indicate that life expectancy is the strongest positive indicator of human potential, positively affecting the scientific and technical potential, and the spread of alcoholism and drug addiction is the strongest negative factor negatively associated with indicators of scientific and technical potential.
VARLIK VE BİLGİNİN KORELASYONU ÜZERİNE BİR DEĞERLENDİRME
Authors: ÇELEBİ Emin , ÖNAL Mehmet
Published: December 2020

Varlık ve bilgi birbirinden ayrılamaz iki kavramdır. Bilginin içeriğini var olanlar oluşturduğu gibi bilgiyi üreten de bir ‘var olan’ varlıktır. Başka bir deyişle bilginin hem öznesi hem de nesnesi genel itibarıyla varlıktır. Ne var ki Modern dönemle birlikte bilgi ve varlık kavramlarının birbirinden uzaklaştırıldığını ve varlık kavramının ikincil planda kaldığını müşahede etmekteyiz. Bilme arzusunun varlık üzerinde tahakküme yol verdiği bu yeni paradigmanın, ürettiği sonuçlar bakımından, bütün var olanlar için bir tehdit oluşturduğunu bizatihi birer var olanlar olarak tecrübe etmekteyiz. Bu itibarla varlık ve bilgi ilişkisinin tekrar sorguya çekilmesi ve aslında olduğu gibi sahih bir biçimde açığa çıkartılması hayati bir önemi haizdir. Bu perspektif ışığında bu çalışmada, Parmenides, Herakleitos, Platon, Aristoteles ve Kant örnekleri üzerinden varlık ve bilgi ilişkisinin nasıl tesis edildiği yorumlanmaya çalışılacaktır.
The physico-mechanical properties of concrete with red-mud at high temperatures
Authors: Alameri Ibrahim A. , Oltulu Meral
Published: December 2020

Reuse of treated waste can provide significant environmental, social and economic benefits. It is necessary to use it in the right places while keeping the properties of the waste in mind. Aluminum-rich wastes such as red mud derived from bauxite may be used in places exposed to high temperatures. This article discusses the effects of high temperatures of 25, 200, 300, 400, 600 and 800°C and 3 hours of exposure on concrete samples replaced by red mud at 0, 10, 15 and 20%. To study the concrete’s mechanical and permeability properties, loss in weight, compressive strength, splitting tensile strength, capillary water absorption and water permeability tests were performed for all mixes. Results were closer to those of the control specimen, which ultimately supported the use of red mud at a ratio of 10%.
An investigation on the properties of woodcrete exposed to high temperature
Authors: Canbaz Mehmet , Kara İlkay , Topçu İlker Bekir
Published: December 2020

By combining wood wastes with various binders, construction materials can be produced. These materials can be used in non-bearing parts such as wall block, insulation panel. In this study, prismatic specimens were taken from the mixtures produced considering the chip-cement ratio as 0.25, 0.5 and 1. The unit weight, ultrasonic pulse velocity, bending and compressive strengths of the specimens were determined by using the results of the experiments on these specimens. In addition, specimens were kept at 200 and 400°C for 3 hours in order to determine its behavior under high temperature, which is one of the most important problems for wood composites. With the experiments carried out on the cooled specimens, weight and strength losses, changes in ultrasonic pulse velocity were examined. As a result of the study, while determining that the chip-cement ratio can be used as 1, it is recommended to use the chip-cement ratio up to 0.5 when the high temperature effect is taken into consideration.
Fracture properties of self-compacting fiber-reinforced concrete
Authors: Ghazy Mariam Farouk , Abd Elaty Metwally Abd Allah , Daboun Omar
Published: December 2020

Self-compacting concrete (SCC) is an innovative concrete that does not necessitate vibration for placing and compaction. Nineteen concrete mixes were investigated including a control mix without fibers as well as eighteen SCC with fibers (SCFRC) mixes. Three types of fibers (polypropylene, glass and steel) were used. Slump flow, L-box, V-funnel as well as column segregation tests were conducted to assess the fresh properties. Whereas, compressive, splitting tensile and flexural strengths were measured to assess the hardened properties of SCFRC. Three point bending tests were performed for the purpose of assessing the fracture properties of SCFRC. Test results showed that the inclusion of fibers to produce SCFRC mixtures remarkably enhanced the fracture properties including fracture energy (Gf) and fracture toughness (K1c). Inclusion of steel fibers with 2% volume fractions showed an improvement with 26.9 times for Gf over the control mix. Whereas, 104% increase in K1c was recorded for the same mix over the mix without fibers. Adding fibers to SCC to produce self-compacting fiber reinforced concrete (SCFRC) will expand its advantages. However, the application fields still need to understand the properties of SCFRC.