bluuebunny/crossref_metadata_2025 huggingface dataset:
Situação das Unidades de Terapia Intensiva do Extremo Norte do Brasil: distribuição de leitos e análise de equidade
Authors: N. de M. Felix Nathalia Cristina , P. Silva Jonathan , V. M. Moraga Lilian Mara , M. Lima Gabrielle
Published: February 2023

Introdução:As unidades de terapia intensiva (UTI) cresceram consideravelmente e tornaram-se responsáveis por grande partedo consumo de recursos dos sistemas de saúde. Este estudo teve como objetivo realizar o levantamento do número de leitosdas UTIs do município de Boa Vista-RR no que se refere à sua quantidade, localização geográfica, entidade mantenedora, tipode atendimento, de clientela e de tratamento, assim como as médias de ocupação e de permanência. Além de promover dadosepidemiológicos com intuito de contribuir para a melhora de oferta do número de leitos para o município. Métodos: Trata-se deestudo de uma revisão bibliográfica de natureza descritiva sobre o tema levantamento do número de leitos de UTI do estado deRoraima. Foram analisados a distribuição e as características dos leitos de unidade de terapia intensiva, assim como as medias deocupação e permanência. Desenvolvimento: Trata-se de estudo de uma revisão bibliográfica de natureza descritiva sobre o temalevantamento do número de leitos de UTI do estado de Roraima. Foram analisados a distribuição e as características dos leitos deunidade de terapia intensiva, assim como as medias de ocupação e permanência. Conclusão: Trata-se de estudo de uma revisãobibliográfica de natureza descritiva sobre o tema levantamento do número de leitos de UTI do estado de Roraima. Foram analisadosa distribuição e as características dos leitos de unidade de terapia intensiva, assim como as medias de ocupação e permanência.
Swimming exercise modifies oxidative stress in skeletal and cardiac muscles of diabetic rats
Authors: F. Pio Talita , E. Orzari Lucas , A. Alves Armindo , C. L. Silveira Paulo , A.M. Esquisatto Marcelo , A. M. de Andrade Thiago , Felonato Maíra , A. Dalia Rodrigo
Published: February 2023

Introduction: Oxidative stress is a key factor leading to the deterioration of diabetes. Oxidative stress exacerbates diabetes and induction of the activity of the antioxidant system may be required to prevent this effect. Objetive: The aim of the present study was to evaluate the redox state in the skeletal and cardiac muscles in a diabetes rat model subjected to swimming exercise for 4 weeks. Methods: Wistar rats were divided into four groups: untrained control (C), trained control (T), untrained alloxan-induced diabetes (D), and trained alloxan-induced diabetes (TD). The redox state of the skeletal and cardiac muscles was assessed by analyzing TBARS, -SH groups, H2O2 production, and SOD and catalase activity. The total number of cardiomyocytes and the total area of collagen fibers in the cardiac muscle were measured by histomorphometry. Results: In the Soleus muscles, the TD group showed increased H2O2 levels and catalase activity compared to the T group, and SOD activity compared to the D group. Regarding the red gastrocnemius, the TD group presented higher SOD and lower catalase activities than the D group. Regarding the cardiac muscle, the TD group presented lower TBARS and higher levels of -SH groups and catalase activity than the D group. Swimming exercise decreased hyperglycemia and reduced pathology, as evidenced by the reduced number of cardiomyocytes and the area of collagen fibers. Conclusion: Swimming exercise in diabetic rats controlled hyperglycemia and oxidative damage, and the reduced fibrosis in the cardiac muscle of diabetic rats.
Targeted Overexpression of NDRG2 using Survivin Promoter Reduces Viability and Invasiveness of A549 Cell Line
Authors: Fanian Maryam , Rafiei Gholamreza , Alizadeh Zarei Marzieh , Takhshid Mohammad Ali
Published: February 2023

Background: Anti-tumor effects of N-myc Downstream Regulated Gene2 (NDRG2) have been demonstrated in many tumors. In the present study, NDRG2 was specifically overexpressed in lung cancer cell line using Survivin Promoter (Sur-P). Then, the effects of NDRG2 overexpression on viability, apoptosis, migration, and invasion of A549 cells were evaluated.
Methods: Recombinant pAdenoVator-Sur-P-NDRG2-IRES-GFP plasmid harboring NDRG2 gene under transcriptional control of Sur-P and mock plasmid were constructed. A549 lung tumor cells and LX-2 cells (non-tumor cell line) were transfected with pAdenoVator-Sur-P-NDRG2-IRES-GFP, pAdenoVator-CMV-NDRG2 IRES-GFP, or mock plasmids. Tumor specificity of Sur-P was evaluated using fluorescent microscopy for GFP expression. The effects of NDRG2 overexpression on cell viability, apoptosis, and migration of A549 cells were measured using MTT, annexinV/7-AAD flow cytometry, and transwell migration assay, respectively. NDRG2 and matrix metalloproteinase-2 (MMP-2) expression were measured using real time- PCR.
Results: pAdenoVator-Sur-P-NDRG2-IRES-GFP transfection resulted in a huge GFP expression in A549 cells, but not in LX-2 cells. The results of real time-PCR analysis also showed that pAdenoVator-Sur-P-NDRG2-IRES-GFP transfection led to an abundant NDRG2 expression in A549 cells. NDRG2 overexpression decreased A549 cell viability through increasing cell apoptosis. In addition, migration, invasion, and MMP-2 expression decreased following NDRG2 overexpression in A549 cells.
Conclusion: The findings indicate that the targeted overexpression of NDRG2 using Sur-P can reduce the viability and invasiveness of A549 cells, suggesting possible benefits of this approach in lung cancer therapy.
Analysis of SLC26A4 Gene in Individuals with Non Syndromic Hearing Impairment in Relation with GJB2 Associated Mutations
Authors: Rajalakshmi Krishna , Thirunavukkarasu Jayakumar , Vikraman Meenu Ambika , Maruthy Santosh , Sylvester Charles , Kundapur Rajesh
Published: February 2023

Background: Hearing Loss (HL) is the most common sensory disorder. HL commonly ranges from mild to severe. Persons with HL face difficulty in hearing conversations or sounds through one ear or both ears, which impacts one’s ability to interact with others. Hence it is a communicable disorder that makes people socially isolated, lonely, and frustrated. HL in children severely affects language development. The people who are referred to as 'Deaf' with very little or no hearing capabilities, are considered as having profound hearing loss. More than 124 genes are causative for Non-Syndromic HL (NSHL) with varying inheritance, among which the SLC26A4 mutations are the second commonest cause of hereditary HL across the globe.
Methods: Samples from 70 NSHL patients were analyzed through Next-Generation Sequencing (NGS) and generated five pathogenic variants [N246fs (rs918684449), K564fs (rs746427774), F122fs, V239D (rs111033256), T721M (rs121908363)] each with frequency of 1.42%. Three missense variants [S399P (rs747431002), L597S (rs55638457), and G6V (rs111033423)] were reported under the "uncertain" category. All the collected samples were further genotyped to look for the possibility of having GJB2 and HL-associated mutations.
Results: Out of five SLC26A4 pathogenic mutations N246fs (rs918684449) and K564fs (rs746427774) were observed in samples which were positive for GJB2-HL associated candidate mutations [W24X (rs104894396), Q124X (rs397516874) and W77X (rs80338944)]. Similarly, pathogenic variants F122fs, V239D (rs111033256) and T721M (rs121908363) were observed in patient samples which were negative for GJB2-HL associated mutations.
Conclusion: Our data will expand the list of variants underlying NSHL and encourage further genotype SLC26A4 gene concerning the south Indian population with a large sample size.
Investigating the Safety and Efficacy of the Synthetic Drug Herbix on Immune Responses Involved in the Treatment of a Mouse Model of Herpes Simplex Virus
Authors: Khodadoust Mohammad Ali , Keramatian Gholam Reza , Farkhad Najmeh Kaffash , Tavakol-Afshari Jalil
Published: February 2023

Herpes simplex virus-1 (HSV-1) infections can cause significant harm to individuals, including blindness, congenital defects, genital herpes, and even cancer, with no definitive cure .so, finding new treatment strategies is crucial.
In this study, 25 male BALB/c mice were used to conduct a mouse model of herpes by subcutaneously injecting an HSV-1 suspension (100 µL of 1×  PFU/mL). The mice were divided into 5 groups with groups 1 to 3 designated as intervention groups, and groups 4 and 5 serving as positive and negative control groups, respectively. After 2 days of virus inoculation, the mice were treated with different concentrations of Herbix (100, 200, and 300 mg/mL) via subcutaneous injection. Mice Blood samples (0.5 to 1 mL) were taken from the mice before and after the experiments, and after three-week follow-up period, the mice were sacrificed and the spleens were removed for lymphocyte analysis.
we found that administration of Herbix at a dose of 300 mg/mL showed the greatest efficacy, characterized by a delay in skin lesion formation, an increment in survival rate and lymphocyte proliferation, upregulation of the gene expression of interferon alpha (IFN-α) and tumor necrosis factor alpha (TNF-α), and an increase in the polarization of cytotoxic and helper T lymphocytes compared to the control group.
These results suggest that Herbix at a dose of 300 mg/mL is effective in treating murine herpes and stimulating immune responses, making it a potential candidate for further investigation as an antiherpetic drug.
The Risk of the Next Child Getting Affected by Chronic Granulomatous Disease in Families with at Least One Autosomal Recessive CGD Child
Authors: Modarresi Seyedeh Zalfa , Tajik Shagayegh , Badalzadeh Mohsen , Fazlollahi Mohammad Reza , Houshmand Massoud , Maddah Marzieh , Alizadeh Zahra , Nabavi Mohammad , Bazargan Nasrin , Movahedi Masoud , Pourpak Zahra
Published: February 2023

Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder more common in autosomal recessive (AR) than X-linked in Iran.
This study aimed to assess whether having a child with AR-CGD would increase the likelihood of the next child being affected by CGD.
Ninety-one families with at least one child affected by AR-CGD entered this study. Out of the 270 children, 128 were affected by AR-CGD. We used a cross tab for the odds ratio (OR) calculation, in which exposure to a previously affected child and the next child’s status were evaluated. This study illustrated that the chances of having another child afflicted with AR-CGD are significantly increased if the previous child had AR-CGD (OR=2.77, 95% CI=1.35-5.69).
Although AR disorders affect 25% of each pregnancy, we showed that the chance that the next child would be affected by CGD, given that the previous child was affected, is 2.77 times greater than in families with a normal child. It is recommended to warn families with one or more affected children to evaluate the risk of CGD in their subsequent pregnancies with prenatal diagnosis.
Power aware air quality sensing system with efficient data storage capability
Authors: Purkayastha Koel Datta , Nath Chayan , Pradhan Sambhu Nath
Published: February 2023

Introduction: This paper presents a portable device of Air QualityMonitoring System (AQMS) based on a sensor platform. The purpose of the study is to power awareness, warning indication, and minimal data storage capability.
Materials and methods: AQMS is developed by embedded design methodology. The software part is based on the C programming language. AQMS device is made up of “transmitter” and “receiver” sections through the Zigbee wireless network. The objective is to collect concentrations of CO, NO2, CO2, humidity, and temperature to check air pollution for health awareness. A power-saving strategy is adopted in the "transmitter" of AQMS through a Demultiplexer circuit. To minimize the space complexity of storage and availability of long-term data, data encoding techniques are implemented.
Results: By implementing switching activity on the sensors in AQMS, the active mode of sensing operations are controlled and a power saving of 18.41% is achieved. Extending the duration of transmission operation increases data storage in the “receiver” unit. Hence, two encoding techniques are developed where real-time data are encoded in binary form: 2-bit encoding and 3-bit encoding. According to the results, 2-bit encoding saves 50% of storage space and 3-bit encoding saves 25%, compared to not utilizing any encoding strategy, sacrificing data accuracy by less than 5%.
Conclusion: AQMS design is created with the implementations of low power consumption and low storage. Additionally, an alarming condition is set in AQMS for indicating the level of pollutants in the air to determine the risk level of exposure which is dangerous for human health.
Source characterization of PM10 using CMB receptor modeling for the western industrial area of India
Authors: Nihalani Seema , Khambete Anjali , Jariwala Namrata
Published: February 2023

Introduction: Receptor models use the chemical characterisation of particulate matter to distinguish the source and analyse the source contributions. The main aim of this study is to carry out source apportionment of PM10 for industrial locations of Vapi and Ankleshwar in Gujarat, using the Chemical Mass Balance (CMB) receptor model.
Materials and methods: At six distinct locations of Ankleshwar and Vapi, respirable dust samplers were used to collect particulate matter on quartz filter sheets for the current study. Filter papers containing PM10 mass were subsequently examined for Water Soluble Ions (WSIs), major and trace elements, elemental and organic carbon followed by source apportionment study.
Results: Using CMB, the contributions obtained for Ankleshwar are 27.85% for crustal or soil dust, 26.31% for fossil fuel combustion, 21.06% for vehicle emissions, 14.20% for secondary aerosols, 9.30% for biomass, and 1.20% for industrial emissions. CMB for Vapi revealed the chief source signatures as fossil fuel combustion including industries contributing 35%, crustal or soil dust contributing 22.90%, biomass burning contributing 19.12%, vehicular emissions contributing 16.18%, and secondary aerosols contributing 6.79%.
Conclusion: By applying the CMB model, the primary source is found to be crustal or soil dust followed by burning fossil fuels, vehicular emissions, and secondary aerosols for Ankleshwar and Vapi, respectively. A quantitative assessment of source contributions to particulate matter is required to create emission control measures. The findings of this study will be beneficial for the environmental management of particle concentrations in the study region.
Wire Extensometer Based on Optical Encoder for Translational Landslide Measurement
Authors: Setiono Andi , Qomaruddin - , Afandi M. Imam , Adinanta Hendra , Rofianingrum Mefina Y. , Suryadi - , Mulyanto Imam , Bayuwati Dwi , Anwar Arif , Widiyatmoko Bambang
Published: February 2023

A landslide is a natural disaster mostly accompanied by heavy rains, earthquakes, or volcanic eruptions. Due to its significant incurred losses, several studies have been conducted to develop a landslide monitoring system. In this report, we built and implemented optical-based wire-extensometers to measure and monitor a translational landslide in a prone area. This extensometer was built of an optical rotary encoder (whose shaft bonded to a spiral spring and sling rope) interfaced to a low-cost microcontroller as a principal component and subsequently linked to a GSM-based wireless network. The working principle of the employed sensor described in this paperwork is to count optical pulse signal and convert it into a length unit. This sensor can provide much better signal stability and show high resolution for a wide-range measurement than voltage- or current-based sensors. The specification of the engaged optical encoder provides 2000 pulses per rotation, leading to a length resolution of 0.011 Â± 0.0083 mm with a speed limit of about 36 mm/s. Furthermore, the wire extensometer was examined in a remote place near a double-track train road to assess its performance in an actual field. A solar cell system was applied as its main power supply. An example of transmitted data shows a land shift from 12 mm to 150 mm, which is mainly triggered by high rainwater infiltration. This result demonstrates that the developed extensometer is deserved to be promoted for landslide monitoring in the geological research-work area.
3D Printed Prosthetic Robot Arm with Grasping Detection System for Children
Authors: Babu Devin , Nasir Abdul , Ravindran - , Farag Mohannad , Jabbar Waheb A.
Published: February 2023

Prosthetic robot arms have been an alternative replacement for upper limb-related disability, especially among children as it helps them perform regular activities such as holding tools, eating, and drinking. This research aims to develop a 3D prosthetic robot arm using SolidWorks and 3D printer, using a low-cost and straightforward mechanism for children. This paper proposes a close loop control system with position control for the prosthetic robot arm to achieve an appropriate grasping force focusing on solid-shaped objects using PID control. The PID controller controls the system's response to perform in the most efficient path. Force-sensitive resistors (FSR) are attached to all fingers to measure the grasping force acting on objects with different surfaces, dimensions, and weights. The controller results showed improvement in the overshoot percentage of 0.902%, as overshoot is essential in preventing the grasped object's deformations. The analysis of the experiment shows that the mean grasping force and static coefficient friction of each object are different regardless of the material the object is made of and the object's mass. For example, a cube-shaped object made of wood requires 0.5288 N of grasping force to grasp the object firmly compared to a plastic-made cube that only requires 0.3245 N to hold the cube. On the other hand, the static coefficient friction for the wood cube is 3.1708 and 0.4725 for the plastic cube. Further research can be done by designing the prosthetic robot arm with independent motorized and multi-degree movement of fingers.
Electrochemical Sensor Based on Molecularly Imprinted Polymer (MIP) for Simazine Pesticide Detection
Authors: Bow Yohandri , Syakdani Adi , Purnamasari Indah , Rusdianasari -
Published: February 2023

The use of pesticides and herbicides containing the active ingredient simazine must be carried out strictly so as not to cause adverse effects on humans and the environment. Measurement of contaminants in the form of simazine as one of the active ingredients of pesticides and herbicides is very important. An imprinted polymer molecule (MIP) has been made using methacrylic acid (MAA) as a functional monomer and ethylene glycol dimethyl acrylate (EGDMA) as a cross-linker. This research resulted in a molecularly imprinted membrane for the specific recognition of simazine. The electrochemical potential used with MIP coated electrodes provides both qualitative and quantitative detection of simazine. Polymer coated molecular-based potentiometric sensors (MIP) are promising analytical tools for developing highly selective analytical sensors. Optimal conditions for the production of simazine MIP were found to be 6.02 mL of chloroform, 0.025 g of simazine, 0.9 mL of MAA, 1.57 mL of EGDMA, and 0.07 g of benzoyl peroxide (BPO) with a heating time of 150 minutes at 70oC. The results of the electrode performance test resulted in stable and unstable conditions, with a measurement range on the surface of the double-layer electrode with a coefficient distribution of 0.9897. Compared with electrochemical procedures with MIPs sensors and spectrophotometry, it produces a significant value with a 95% confidence level with Q-test results for the 0.48 ppm level with spectrometric procedures obtained Q exp = 0.25, Q crit value is 0.71.
A Dataset-Driven Parameter Tuning Approach for Enhanced K-Nearest Neighbour Algorithm Performance
Authors: Inyang Udoinyang G. , Ijebu Funebi F. , Osang Francis B. , Afoluronsho Aderenle A. , Udoh Samuel S. , Eyoh Imo J.
Published: February 2023

The number of Neighbours (k) and distance measure (DM) are widely modified for improved kNN performance. This work investigates the joint effect of these parameters in conjunction with dataset characteristics (DC) on kNN performance. Euclidean; Chebychev; Manhattan; Minkowski; and Filtered distances, eleven k values, and four DC, were systematically selected for the parameter tuning experiments. Each experiment had 20 iterations, 10-fold cross-validation method and thirty-three randomly selected datasets from the UCI repository. From the results, the average root mean squared error of kNN is significantly affected by the type of task (p9000, as optimal performance pattern for classification tasks. For regression problems, the experimental configuration should be7000â‰¤SSâ‰¤9000; 4â‰¤number of attributes â‰¤6, and DM = 'Filtered'. The type of task performed is the most influential kNN performance determinant, followed by DM. The variation in kNN accuracy resulting from changes in k values only occurs by chance, as it does not depict any consistent pattern, while its joint effect of k value with other parameters yielded a statistically insignificant change in mean accuracy (p>0.5). As further work, the discovered patterns would serve as the standard reference for comparative analytics of kNN performance with other classification and regression algorithms.
Evaluation of Land Suitability for Cacao in Takapala Watershed Using Geographic Information System
Authors: Umar Ramli , Abidin Muhammad Rais , Falah Muh. Darwis , Zhiddiq Sulaiman , Suprapta -
Published: February 2023

Due to the great variety of land resources in Indonesia, there is a wide range of levels of land appropriateness for various commodities. In order to provide the most physically feasible cultivation pattern and the greatest possible economic results, a land plan is required. This study aims to determine the suitability level of cocoa plantations in the Takapala Watershed (Jeneberang Sub-watershed) using a geographic information system (GIS) method with overlays of slope maps, geomorphological maps, soil type maps, and land use maps. According to the analysis's findings, the Takapala watershed's area is suitable for growing cocoa (Jeneberang Sub-watershed). Obtaining five land suitability sub-classes, including S2 extremely appropriate (with a 93.94 ha area), S3-W1 (marginally suitable class with a factor of 0.8), and S4-W1 (not at all suitable class) as a limiting factor for rainfall 1022.33 Ha with marginally suitable class. There is very good potential for cocoa plant growth in the Takapala Watershed, where the land adaptability level can reach 69.6%. This demonstrates that cocoa trees can develop into crops that can be grown in the Takapala watershed. On the one hand, the Takapala Watershed's topography will present a barrier to cacao development, needing specific approaches to cacao production. Future research should, it is anticipated, look into how cocoa plants should be managed in environments with steep-to-steep slopes.
IoT-Based Air Conditioning Control System for Energy Saving
Authors: Waluyo - , Widura Andre , Hadiatna Febrian , Fikri Ridwan Syamsul
Published: February 2023

A high portion of electric consumption is air conditioning in householders or offices, reaching 42%. Therefore, it is necessary to automatically regulate air conditioning operations for energy saving using a control system, usually involving its hardware. As another option, the control system also involves electronic devices and software. This research developed an automatic control system using an ESP32 microcontroller integrated into the Blynk-based internet of things (IoT) for energy-saving air conditioning. The ESP32 was programmed using Arduino IDE and combined with a motion sensor to maximize energy saving. The motion sensor was a trigger to turn on the system. The recorded data were current, voltage, power, temperature, and motion detection. Based on the recorded power, the consumed energy was computed using trapezoidal and Simpson's composite rules of numerical integrations and ordinary methods. The testing was conducted in conventional, manual, and automatic operations. The yielded automatic control system operated adequately. The testing results revealed that the automatic operation saved 1.15 kWh (15.00%),0.99 kWh (13.66%), and 1.14 kWh (14.87%) average daily energy compared to the conventional operation, respectively, by using the ordinary, Simpson's composite rule, and trapezoidal composite rule computations. While the automatic compared to the manualmethodssaved1.68 kWh (20.44%), 1.78 kWh (22.14%), and 1.66 kWh (20.24%), respectively, for the same computations. Thus, the automatic system considerably saved energy compared to conventional and manual operations. Moreover, these energy savings were also higher than some previous research on air conditioning energy savings.
Prediction of Drug Demand Based on Deep Learning Approach and Classification Model
Authors: Yanto Musli , Arlis Syafri , Putra Muhammad Reza , Syahputra Hadi , Ariandi Vicky
Published: February 2023

The high demand for drugs in the last period has caused problems with drug shortages in several pharmacies. Almost all pharmacies experience the same problem, causing many people who do not to get their drug needs during the current pandemic. To overcome this, analyzing the process of predicting drug demand in the next period is necessary. The prediction process can be used as an initial solution in solving problems to see the number of drug demand numbers that will occur. This study aims to develop a predictive analysis model for drug demand using a deep learning approach and a classification model. Deep learning is an approach that does well in the case of prediction. The classification model also includes the right concept for solving the problem. The prediction and classification analysis methods include K-Means clustering, Multiple Linear Regression (MRL), Artificial Neural Network (ANN), and Decision Tree algorithms C.45. This method can provide better performance results in the prediction process to get precise and accurate output. Prediction results obtained from the learning process provide an accuracy rate of 99.99%. The output of the classification model also provides an overview of the knowledge base in the form of a decision tree. The level of classification model testing carried out gives the accuracy of the classification pattern of 97.05% so that the analytical model developed can predict future drug demand.
Why is Applying a Complete Product Sorting Technique Essential for Empowering Cococraft Craftsmen?
Authors: Dumasari Dumasari , Dharmawan Budi , Budiningsih Sulistyani , Santosa Imam
Published: February 2023

Applying a complete sorting technique is essential for the empowerment of cococraft craftsmen. However, complete sorting is often overlooked. Mixed products make the price the same. The research objective is focused on studying the benefits of applying complete sorting techniques to the empowerment of cococraft craftsmen. The research location is a cococraft production center located in Purbalingga Wetan, Purbalingga Regency, Central Java Province, Indonesia. The types of research data are primary and secondary. The research method is a descriptive case study with a qualitative-quantitative approach. The results showed that most respondents simply sorted raw materials, shapes, and sizes. Few respondents did complete sorting. Complete sorting is beneficial in increasing the respondent's ability to group products according to quality, estimate the right price, reduce price cuts, increase service, speed up sales time, expand marketing, guarantee customer markets, ease of marketing, inflation, increased mutual trust, establish business cooperation and social relations. The price of cococraft with the whole sort is higher, thus increasing revenue. Complete sorting includes selecting raw materials, shape, size, organ integrity, physical strength, color, texture pattern, surface smoothness, production status, durability, and practical benefits. The application of complete sorting techniques needs to be continuously diffused to craftsmen so they can obtain various functional benefits that support empowerment. Critical diffusion comprises regular consultative advocacy facilities between experienced craftsmen and others.
Risk Factors in Depression and Anxiety Disorders from the Framework of Developmental Psychopathology
Authors: GÖKDAĞ Ceren , KIZILTEPE Rukiye
Published: February 2023

Depression and anxiety disorders are among the most prevalent psychiatric disorders that negatively affect individuals’ life in many ways. Understanding how these highly comorbid emotional disorders develop and persist might guide prevention, intervention, and treatment studies. Some common vulnerability factors underlie depression and anxiety disorders. Developmental psychopathology deals with these vulnerabilities and risk factors from a lifetime perspective. The aim of this review is to present the risk factors associated with depression and anxiety from the perspective of developmental psychopathology. For this purpose, we discussed genetic and biological factors, temperament, negative childhood experiences, family and peer relationships, and some cognitive and emotional factors as risk factors. Also, we discussed how these risk factors lead to depression and anxiety disorders. This review emphasizes that some common transdiagnostic risk factors underlie emotional disorders and highlights the importance of a developmental psychopathology perspective to understand the developmental pathways of depression and anxiety disorders.
Analysis of Studies about Academic Anxiety: A Thematic Review
Authors: BÜLBÜL Kenan , ODACI Hatice
Published: February 2023

The aim of this research was to analyze academic anxiety studies in the literature using the thematic review method and to determine the current trend in this field. In the research, a meta-synthesis study was carried out including 61 studies, 3 of which were theses and 58 were articles, published between 1981-2021. The studies used in the research were accessed in Dissertations and Theses Global-Proquest, Eric-EBSCOhost, MEDLINE, Science Direct, Scopus, SpringerLink, Taylor and Francis Online, Wiley, ULAKBIM, YÖK Thesis Center and Google Scholar databases. Published articles or theses about determining the nature of academic anxiety in the literature were included in the study. In the examined studies, the relationship of academic anxiety with more than one variable was investigated and it was determined that most studies focused on examining the differences based on demographic variables. The survey model was the most frequently chosen research method, and qualitative research methods were not sufficiently used. The studies examined were carried out mostly by using the questionnaire method in high school level age groups and sample groups of 101-300 people. Therefore, in order to carry out new studies with larger working groups, to examine the academic anxiety of students at higher education level and to carry out reviews, scale development or adaptation studies for higher education students are needed. In addition, there was a limited number of experimental studies conducted about reducing student academic anxiety. Survey and relational based quantitative research needs to be supported by experimental methods.
Relationship of Cryptocurrencies with Gambling and Addiction
Authors: ŞENTÜRK Erman , COŞAR Behçet , ARIKAN Zehra
Published: February 2023

Cryptocurrencies has been considered as both an investment tool and a great invention that will replace money and change the world order. Although crypto currency trading has been investigated in many aspects, the psychological dimension that directly affects investors has often been ignored. Control of cryptocurrency trading is in the hands of investors rather than a central authority or institution. Thus, the value of cryptocurrencies changes with the reactions of investors. This situation suggests that psychological factors may be more prominent in cryptocurrency trading. Cryptocurrency trading has many similarities with gambling and betting, such as risk taking, getting quick returns, extreme gains or losses. Some significant components of behavioral addiction are also seen in individuals who spend so much time with cryptocurrency trading. The purpose of this article is to provide a better understanding of the psychological effects of cryptocurrency trading, which has entered our lives over a relatively brief period of time and reached millions of investors.
Impact of Parental Representations and Related Parenting Behavior On Children
Authors: ÖZTÜRK Cansu , GÜZEL Halime Şenay
Published: February 2023

Parental representations tend to be formed in the prenatal period and affect the child- parent relationship in the long term. Therefore, in the clinical environment, it is important to define parents’ representations to increase the success of therapeutic interventions and prevent childhood psychopathologies with various intervention programs. With this concern, the aim of this review was to summarize the literature about parental representations and their relationship between parenting behavior, and childhood developmental problems. Related to this purpose, this review includes the definition and categories of parental representations, the factors which contribute to parental representations, and the relations between parenting and childhood developmental problems.
The Effect of Vitamin Use During Pregnancy on First Tooth Eruption Time in Postpartum Period
Authors: BAYRAMOĞLU Zeynep , CİMİLLİ ŞENOCAK Gamze Nur , KILIÇ Munevver , KAŞALİ Kamber
Published: February 2023

Objective: Vitamin supplements are commonly used to support the nutritional status of pregnant women during gestation. In this multidisciplinary study, we discussed the relationship between the three most used vitamin supplements in the Turkish population (vitamin D, vitamin B complexes, and multivitamins prepared for pregnant women) during pregnancy and tooth eruption time in babies.

Methods: The data of approximately 1,000 patients who gave birth in the obstetrics and gynecology clinic of our university were retrospectively reviewed. The babies of 145 patients who could be reached and who met the inclusion criteria were followed up in their postnatal period. Babies' first tooth eruption time, presence of caries, use of breast milk, and number of missing or excess teeth according to the month were determined.

Results: No statistically significant differences were found between the groups regarding maternal age, infant age, number of caries, breast milk use, or the number of missing/excessive teeth. However, it was found that patients who took vitamin D + B and patients who took only vitamin B had significantly earlier first tooth eruption times than those who used all three vitamins. The patients who used three vitamins had the latest tooth eruption time. There was no statistically significant difference between first tooth eruption time and maternal age or breast milk use.

Conclusion: The use of vitamins in pregnant women can affect babies' oral–dental systems, which develop while they are still in their mother's womb. More detailed information on the use of vitamins is needed in the future
Pengembangan Model Pembelajaran Nobangan Berbasis Permainan Tradisional Suku Kaili terhadap Nilai Karakter Cinta Tanah Air
Authors: Azizah Azizah , Sani Nurul Kami , Aras Nurul Fitriah , Adriana Lusi
Published: February 2023

Penelitian ini bertujuan untuk mengembangkan model pembelajaran nobangan berbasis permainan tradisional yang berasal dari Suku Kaili dalam pembelajaran di sekolah dasar terhadap nilai karakter cinta tanah air. Metode penelitian yang digunakan yaitu  metode penelitian dan pengembangan (R & D) yang diadopsi dari model R & D tiga fase dari Gravemeijer & Cobb. Tiga fase tersebut yaitu fase penelitian awal, fase pengembangan, dan fase pengujian. Subjek penelitian adalah siswa sekolah dasar di Kota Palu. Hasil penelitian yaitu dihasilkan model pembelajaran nobangan berbasis permainan tradisional suku Kaili terhadap nilai cinta tanah air yang valid dan praktis. Model ini dapat mengembangkan nilai karakter cinta tanah air siswa karena berbasis permainan rakyat yang menyenangkan bagi siswa dalam mengikuti pembelajaran. Simpulan bahwa model pembelajaran nobangan terhadap nilai karakter cinta tanah air yang dikembangkan memiliki kriteria valid dan praktis. Penerapan permainan nobangan dalam pembelajaran, membuat siswa lebih memahami kebudayaan suku Kaili. Dengan demikian, nilai-nilai tradisional suku Kaili tetap terjaga dan terlestarikan.
Optimalisasi Peran Sekolah dengan Analisis Interaktif bagi Penguatan Pendidikan Karakter
Authors: Hendri  , Utami Ichwani Siti , Nurlaili Lili
Published: February 2023

Warga Negara Indonesia menjunjung tinggi adab atau akhlak menjadi suatu keniscayaan bagi seluruh lapisan masyarakat. Pemerintah memperhatikan hal tersebut, karena berperan untuk membuat warga memiliki karakter. Tujuan penelitian ini untuk menganalisis optimalisasi peran sekolah bagi penguatan pendidikan karakter. Sasaran penelitian yaitu peserta didik di SMPN 02 Ciseeng, desa Kuripan. Penelitian ini menggunakan metode deskriptif dengan pendekatan kualitatif. Teknik pengumpulan data penelitian menggunakan wawancara, observasi dan dokumentasi. Teknik analisis data menggunakan analisis interaktif yang dimulai dari pengumpulan data, reduksi, penyajian, dan kesimpulan. Temuan penelitian menujukkan bahwa: pertama, keteladan guru dan seluruh stakeholder sekolah mampu memberikan dampak positif pada karakter siswa. Kedua, lingkungan dan budaya sekolah yang baik berpotensi pada perkembangan karakter siswa. Ketiga, seluruh aktivitas sekolah yang dibuat melalui musyawarah mufakat yang bertujuan mendisiplikan karakter siswa yang ada. Jadi, penguatan pendidikan karakter tidak dapat dipisahkan dari budaya sekolah sebagai lembaga pendidikan yang menciptakan dan menekankan pada tingkat intelektual dan emosional siswa.
Penguatan Karakter Bela Negara di Era Revolusi Digital Melalui Pendidikan Kewarganegaraan
Authors: Subagio Hani , Yulianto Wahyu Wibowo Eko , Prasetyo Danang , Muharam Ricky Santoso
Published: February 2023

Penelitian ini bertujuan untuk mengungkap kontribusi pendidikan kewarganegaraan di perguruan tinggi sebagai sarana penguatan karakter bela negara. Penelitian ini menggunakan pendekatan deskriptif kualitatif dengan data primer berasal dari wawancara, dokumentasi, observasi, serta data kuesioner, sedangkan data sekunder dari referensi ilmiah yang diambil dari web, buku, dan jurnal ilmiah. Upaya yang dilakukan dengan cara memanfaatkan media sosial sebagai sarana edukasi masyarakat terkait dengan pemahaman materi pendidikan kewarganegaraan dan memanfaatkan media sosial untuk menggunggah bukti aktualisasi nyata bela negara, sehingga memberikan inspirasi bagi warga negara lainnya. Selain itu mahasiswa mampu menganalisis berdasarkan kasus-kasus yang disajikan bahwa perilaku warganet di sosial media merupakan bagian dari upaya bela negara di era digital. Terbukti 207 responden menjawab bahwa yang dilakukan oleh warganet terhadap berbagai kasus merupakan bagian dari upaya bela negara. Selanjutnya 11 responden menjawab tidak dan 14 responden menjawab ragu-ragu. Hal yang dilakukan warganet di media social dengan memberikan komentar pembelaan apabila terdapat pemberitaan yang merugikan nama baik Indonesia dan dukungan moral.
Pendidikan Anak Usia Dini tentang Toleransi Beragama sebagai Implementasi Sila Pertama Pancasila
Authors: Tirza Juliana , Cendana Wiputra , Araini Tia Kartika
Published: February 2023

Pengetahuan yang kurang tentang sila pertama Pancasila, mengakibatkan konflik antar agama, dan perbedaan dalam masyarakat Indonesia. Anak usia dini (0-6 tahun) menjadi masa terbaik mengajarkan prinsip-prinsip dalam Pancasila. Penulisan ini bertujuan untuk mengetahui metode terbaik, unsur pembatas dan pendukung, serta pola pendidikan Pancasila, khususnya toleransi beragama pada pendidikan anak usia dini (PAUD). Metode penelitian ini adalah tinjauan pustaka. Temuan menguraikan tentang proses berpikir anak usia dini yang belum luas, maka pendidikan anak usia dini tidak bisa disamakan dengan pendidikan orang dewasa. Dalam praktiknya, metode pembelajaran menyertakan gambar dan narasi, peran orang tua dan instruktur sangat penting, sehingga individu tersebut dapat lebih siap belajar. Metode terbaik yang dapat digunakan dengan demikian adalah media yang menarik seperti menggunakan cerita berseri atau gambar. Metode ini juga cocok dengan usia siswa yang masih kecil yang mana cara berpikir, tindakan dan perilaku masih sempit. Metode ini juga membantu siswa TK untuk menumbuhkan toleransi beragama sejak dini.
Penguatan Civic Culture Berbasis Nilai Kearifan Lokal Melalui Eksistensi Pencak Silat Sebagai Kebudayaan Daerah
Authors: Juwandi Ronni
Published: February 2023

Tujuan penulisan ini adalah untuk mengetahui nilai-nilai yang terdapat dalam pencak silat jurus baku kaserangan sebagai civic culture di Kabupaten Serang. Penulisan ini dilakukan di tiga sekolah yang direkomendasikan oleh Dinas Pendidikan dan Kebudayaan Kabupaten Serang yaitu di Sekolah Menengah Pertama Negeri 1 Pabuaran, Sekolah Menengah Pertama Negeri 1 Ciruas, dan Sekolah Menengah Pertama Islam Al-Hikmah dengan menggunakan metode kualitatif deskriptif. Pengumpulan data menggunakan teknik observasi, wawancara, dan dokumentasi. Hasil penulisan ditemukan adanya nilai-nilai budaya yang mengarah pada perkembangan karakter yang dapat terbentuk dalam proses pembelajaran silat baku kaserangan. Nilai-nilai tersebut diantaranya nilai teori, nilai ekonomi, nilai agama, nilai seni, nilai kuasa dan nilai solidaritas. Adapun karakter yang terdapat dalam silat jurus baku kaserangan adalah religius, disiplin, kerja keras, mandiri, komunikasi/bersahabat, cinta tanah air, tanggung jawab dan menghargai prestasi. Dalam perkembangannya terdapat kendala yang ditemukan yaitu keterbatasan perlengkapan musik pencak silat, keterbatasan pelatih silat kaserangan disekolah dan belum adanya pelatihan bagi pemusik atau “Nayaga”. Kemudian dari kendala tersebut, pemerintah mengupayakan pengembangan pencak silat melalui media pengembangan ekstrakurikuler sekolah dan kegiatan Festival.
Downscaling the Z–R relationship and bias correction solution for flash flood assessment in a data-scarce basin, Thailand
Authors: Mapiam Punpim Puttaraksa , Sakulnurak Sikarin , Methaprayun Monton , Makmee Choowit , Marjang Nat
Published: February 2023

Weather radar is a form of alternative indirect rainfall measurement for use in mitigating flash flood hazards. It is a challenging task to obtain accurate radar rainfall data without integration with automatic rain gauge networks. This paper investigated transformation equations to convert the calibrated daily Z–R relationship to the sub-hourly scale and proposed optional schemes for downscaling the daily bias adjustment factor into 15 min resolution scale to produce a high-resolution radar rainfall product for flash flood modelling. Radar reflectivity data from three radar stations in Thailand and their corresponding daily gauge rainfall data were used in the analysis. Two bias adjustment schemes (DMFB and DS_DMFB), accounting for the temporal variation, and one spatiotemporal scheme (SPTB_IDS) were used to generate three corresponding rainfall datasets for the unified river basin simulator (URBS) model to simulate flood hydrographs in the Tubma basin, Thailand. The results showed that combining the proposed 15-min Z–R scaling equation and the SPTB_IDS produced the most reliable radar rainfall amount leading to an increase in the accuracy of flood modelling with the lowest uncertainty. This indicated that the temporal downscaling solution together with spatial interpolation technique for sub-hourly radar rainfall assessment could benefit flash flood simulation in a data-scarce basin.
Кризисы детского возраста и их преодоление
Authors: Сладкова Юлия Д.
Published: February 2023

Опираясь на периодизацию Л. С. Выготского, в статье проводится анализ шести основных кризисов детского возраста (кризис новорожденности, кризис одного года, кризис трёх лет, кризис семи лет, кризис тринадцати лет, кризис семнадцати лет). В данной статье впервые рассмотрены все шесть детских кризисов и даны рекомендации по их благополучному преодолению. Во введении автором раскрыта сущность детских кризисов, они описаны как особые этапы развития ребёнка. В «Теоретическом обосновании» рассмотрены особенности детских кризисов согласно мнению разных авторов, раскрыто определение понятия «кризис». Также в статье выделены факторы возникновения кризисов и формы их протекания. Для каждого возрастного кризиса подробно описаны новообразования и способы положительного преодоления критического периода. Затронуты положительные и отрицательные стороны прохождения кризисов ребёнком. Автором раскрываются три основных взаимосвязанных между собой вида отношений к окружающей действительности – отношение к самому себе, к другим людям и к предметному миру. Подробно раскрывается проблема влияния кризисов детского развития на взаимодействие с окружающими людьми.  Раскрыты особенности и стили взаимодействия воспитателя и воспитанника, описаны формы взаимодействия родителей и педагогов с ребёнком. Акцент ставится на взаимодействии ребёнка не только совместно с родителями, но также и с воспитателями и учителями. Автором раскрыты формы взаимодействия воспитателя (педагога) и ребёнка для преодоления кризисных явлений в его развитии. В разделе «Заключение» раскрывается важность совместной помощи (родителей и педагогов) ребёнку, которая способствует благополучному протеканию трудных периодов развития. Именно комплексная работа родителей, воспитателей/педагогов способна не оттолкнуть ребёнка, а наоборот, помочь ему в успешном разрешении кризисных ситуаций; для ребёнка такие моменты являются значимыми, а их успешное прохождение будет способствовать развитию эмоциональной устойчивости, открытости и эмпатии.
Modal analysis of a four-bar linkage MEMS microgripper with co-operative electrostatic actuation
Authors: Rossi A.
Published: February 2023

Abstract. MEMS-Technology based microgrippers have been recently used in different fields of applications. These microsystems can be actuated by means of electrostatic actuators, such as linear or rotary comb drives, but the robustness and feasibility of such components in static and as well as dynamic conditions still raises some concerns. In order to contribute to fill this gap, the dynamic properties of a MEMS-Techology Based silicon microgripper, based on four-bar linkage, with co-operative comb-drives, are here numerically analysed. The analysis of the vibrations is essential in many MEMS applications since vibrations may lead to significant positioning errors or undesirable contacts between the anchored and floating fingers of the comb-drives. The present investigation aims to assess the critical modes of a MEMS microgripper in order to ascertain the possibility of impact between the fixed and moving fingers of the comb-drives. The relative displacements between the anchored and the floating fingers are tolerable only if the center of the relative rotation is coincident with the center of the conjugate profiles. Hence, the nature of the relative motion for the first vibration modes has been assessed by means of Finite Element Analysis (FEA) in order to avoid operational issues.