bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimal Control Analysis of Isolation and Treatment Strategies on the Transmission Dynamics and Control of Lassa Fever
Authors: Anka G.H. , Abdulrahman S. , Haliru A.A. , S.S. Manga S.S. Manga , Abubakar S.F.
Published: December 2024

This study constructed and examined a mathematical model on the dynamics of Lassa fever transmission and control. We took into account two interacting rodent and human populations. There are six groups within the human population, one of which is made up of people who underwent complicated recovery. Additionally, there are three divisions within the rodent population. The reduction of susceptible, latent, and infectious individuals by treatment and isolation is the main goal of this work. The goal of optimality is to reduce the number of latent and infectious individuals through isolation and treatment. The amount of influence of the controls in lowering the population of causal pathogens and susceptible, latent, and infectious people is determined by applying the optimal control theory. The model's optimal solution was established using Pontryagin's maximum principle, and the optimal system was then generated and solved numerically. Graphs were used to create simulations showing how the controls affected susceptible, latent, and infected persons. The results demonstrated that applying the two controls simultaneously can be one of the quick and efficient strategies to regulate Lassa Fever.
Acupuncture Therapy for Back Pain in Horses
Authors: Musa Mayaki, Abubakar
Published: December 2024

The treatment of equine back pain (EBP) is very challenging and often not very successful. The relatively low efficacy of current treatment regimens for EBP is mainly associated with nonspecific and multifactorial causes of the condition. This has concerned the equine industry, leading equine practitioners and horse owners to seek alternative and traditional cures to treat the condition. One of the alternative therapies is acupuncture, a technique rarely used on horses with back pain.  Although acupuncture is still a controversial technique among veterinarians, equine practitioners are now exploring the method to treat disease conditions in their horses. There is no doubt that acupuncture alone or as an adjunct therapy to modern medicine has significantly improved the recovery rate of equine back pain. This review looks at the use of acupuncture in the treatment of EBP. Various available acupuncture techniques and their mechanisms of action are discussed.
Performance Assessment of Viscous Dissipative Fluid Due to Heat Source/Sink in a Slit Microchannel
Authors: Onwubuya Isaac Obiajulu , Ojemeri Godwin , Uko Michael A.
Published: December 2024

The focus of this article is to scrutinize the performances of viscous dissipation, porous medium and super-hydrophobicity on free convection of an electrically conducting fluid across an upstanding microchannel affected by an imposed magnetic field. The plates were alternatively heated and incorporated with heat source/sink effect. The steady state expressions of the formulated differential equations have been solved using a semi analytical method (regular perturbation). It is interesting to report that the heat gradient and fluid motion are significantly propelled for mounting values of Brickman number, Darcy porous number and heat source parameters in the superhydrophobic microchannel. On the other hand, the velocity deteriorates for increasing levels of magnetic field and heat sink factors. Further, the comparison of this present analysis with previously published literature for limiting cases when K=1000, so that the term 1/K disappears, demonstrate an excellent relationship, thereby authenticating the accuracy and correctness of this present work. Nuclear power plants, gas turbines and the various propulsion devices for aircraft, missiles, satellites and space vehicles are examples of such engineering areas where this study can find relevance.
Tecnologia Educacional Assistiva: definindo o termo
Authors: Lima Roceli P. , Portella Fabiani O. , Henriques Renato Ventura Bayan
Published: December 2024

Esta pesquisa propõe uma discussão inicial entre a área da Tecnologia na Educação em Computação (TEC) e a Tecnologia Assistiva (TA) na perspectiva da inclusão da pessoa com deficiência (PcD) no contexto educacional. Atualmente, observa-se o amplo desenvolvimento de ferramentas da TEC para apoio ao processo de ensino e aprendizagem. Por outro lado, a área de TA, antes focada na criação de produtos e recursos visando a autonomia das PcD, tem-se destacado como tecnologia educacional inclusiva. Reconhecemos que nem todas as ferramentas educacionais são inclusivas, assim como nem todas as Tecnologias Assistivas são educacionais. Dessa forma, realizamos esta reflexão inicial sobre a convergência entre essas áreas, propondo a definição do termo Tecnologia Educacional Assistiva. Para isso, realizamos uma Revisão Sistemática da Literatura (RSL) e apresentamos uma definição conceitual clara e objetiva deste termo, bem como possíveis desdobramentos científicos.
ASCIIMATH e SONORAMAT: A aprendizagem da matemática por deficientes visuais no ambiente online com o uso de tecnologias digitais
Authors: Santos Andreza C. , Dias Angélica
Published: December 2024

O Ensino a Distância (EAD) está cada vez mais popular, especialmente no ensino de matemática. Esta pesquisa investiga a aceitação de ferramentas digitais, como o ASCIIMATH e SONORAMAT, em um Ambiente Virtual de Aprendizagem, tendo como base o Modelo de Aceitação de Tecnologia (TAM). Professores-alunos de um curso nacional de Aplicação de Ferramentas Computacionais para Apoio ao Ensino de Matemática para Alunos com Deficiência Visual foram estudados. A metodologia incluiu uma etapa qualitativa de estudo de caso e uma etapa quantitativa com questionários. Os resultados indicam a importância das tecnologias assistivas no ensino de matemática. Os resultados desta investigação permitiram conhecer melhor o fenômeno de adoção de tecnologias assistivas, e assim elaborar estratégias de melhoria ao ensino inclusivo, para reduzir a evasão e melhorar a captação de alunos em ambientes virtuais de aprendizagem.
A Practical Guide to Establishing a Molecular-Based Point-of-Care Testing Network for Chlamydia
Authors: Shephard Mark , Matthews Susan , Andrewartha Kelly , Hewer Gabi , Smith Kirsty , Causer Louise , Guy Rebecca
Published: December 2024

This chapter provides a ‘how to guide’ to set up and manage a molecular-based point-of-care (POC) testing network to detect Chlamydia trachomatis (Chlamydia) in populations experiencing high burden of infection and sequelae as well as barriers to accessing routine laboratory services. The chapter outlines the experience of the Australian-based Test, Treat and Go (TTANGO) program which, to the authors’ knowledge, represents the largest decentralised POC testing network for chlamydia (as well as gonorrhoea and trichomoniasis) in the primary care sector globally. The chapter provides an overview of the program’s evolution from a randomised controlled trial through implementation, translation, and scale-up phases to a now national routine program with associated testing rebates. The chapter will examine the governance, training and quality management, and connectivity processes that underpin the TTANGO network and describe the clinical, cultural, operational and economic effectiveness of the network. Collectively, these elements provide a template for translation to low- and middle-income countries (LMIC) where Chlamydia trachomatis remains a significant contemporary health problem.
Docility, Collaborative Learning, and Continuous Innovation: A Case Study of Celebrity Chefs
Authors: McMillan Charles
Published: December 2024

In adaptive organizations, there are strong cultural norms of social interaction that foster two-way communications and listening skills and give take advice giving, to enhance knowledge transfer among teams and individuals. Such norms use docility mechanisms, a social construct that empowers knowledge diffusion in both explicit knowledge and tacit knowledge based on experience, training, and cultivation of craft skills. Adaptive organizations combine both explicit knowledge and routines to assure optimal output, and a social culture to seek innovative measures where high docility and social interaction are central adaptive mechanisms. This paper explores the role of celebrity chefs who, as purveyors of haute cuisine in food culture, achieve global reputations by their training, expertise and knowledge of food habits, and cultivating junior chefs using docility mechanisms and high social interaction. Through TV competitions and cooking programs, they serve as examples of docility and social learning, requiring non-hierarchical collaboration to transfer knowledge between those who want to learn and those who want to teach.
Detection and Typing of Staphylococcus aureus Strains in Pediatric Population of Mexico City
Authors: Bustos-Hamdan Anaid , González García Samuel , Antonio Guzmán Salgado Juan , Hamdan-Partida Aída , Bustos-Martínez Jaime
Published: December 2024

Staphylococcus aureus is one of the main bacteria that infect humans. The pediatric population is susceptible to this microorganism; in Mexico there are not enough epidemiological studies on this subject, so the objective of this work was to detect and typify S. aureus strains in an apparently healthy pediatric population of daycare centers and schools. Nasal and pharyngeal exudates were collected to determine the presence of these bacteria and typed as HA-MRSA or CA-MRSA strains by determining SCCmec, mecA gene, Panton-Valentine leucocidin (PVL), phenol-soluble modulin (psm), and spa-type. It was found that 62.55% of the population were carriers of S. aureus, with a higher percentage in the pharynx and in children older than 4 years of age. A total of 7.04% were carriers of MRSA strains, of which 14.64% were HA-MRSA strains and 85.36% were CA-MRSA strains. The strains showed resistance to several antibiotics. About 20% of the MRSA strains had PVL and psm genes. The strains presented a great variety of spa-types. A high number of S. aureus carriers were found in the pediatric population studied, with the presence of CA-MRSA strains, so surveillance and decolonization programs should be established.
Ion Adsorption and Hydration Superlubricity
Authors: Han Tianyi , Zhang Chenhui , Luo Jianbin
Published: December 2024

The surface-water interactions are pivotal in interfacial functions and properties relevant in many natural processes, particularly the lubrication systems of living organisms, like the articular cartilage, oral mucosa, cardiovascular system, muscle, and tendon tissue. The ion adsorption often determines interfacial lubrication performance, especially hydration superlubricity, which depends on the surface charge characteristics and ion types. The hydration superlubricity mechanism has been well understood over the past 30 years, which further promotes the exploration and development of artificial hydration lubrication materials inspired by nature. This review first introduces the basic properties of the solid–liquid interface and the superlubricity system related to hydrated ions. Then, the influencing factors and mechanism of interfacial ion adsorption on hydration superlubricity are presented. Subsequently, negatively charged materials based on overall modification are summarized, including modified PEEK and modified UHMWPE with ultra-low friction coefficient and ultra-low wear rate. Finally, the potential application of such materials in artificial joints and underwater equipment systems are put forward. It is projected that interest in ion adsorption and hydration superlubricity from the basic science and engineering communities will continue to accelerate in the near future, accompanied by the concept of superlubricitive engineering.
مؤیده‌های حمایت از حق حیات انسان در پرتو آموزه‌های اسلامی
Authors:   پوهنملِ دیپارتمنت تعلیمات اسلامی، پوهنځی/ دانش‌کدۀ شرعیات، پوهنتون/ دانش‌گاه هرات، هرات، افغانستان, منیب بشیراحمد
Published: December 2024

مسألۀ حیات به‌طور مطلق در جهانِ هستی از اهمیت خاصی برخوردارد است. فرقی هم ندارد، که این حیات متعلق به‌ کدام بخش از جهان هستی است؛ چون حیات برای طبیعت نیز دارای همان اهمیتی است که برای انسان اهمیت دارد؛ ولی حیات برای انسان از ارزش ویژه‌یی برخوردار است؛ زیرا او موجودی است متفاوت و برتر که تمام هستی و طبیعت برای بقای او و در خدمت او هستند. موضوع حیات از اهم مباحث در حوزۀ حقوق بشری محسوب می­‌شود، و اسلام باتکرار از این حق انسانی دفاع نموده است. خداوند (ج) محافظت از حیات یک انسان ­را برابر با حیات‌بخشیدن به همۀ بشریت دانسته و سلب این حق ­را برابر با سلب حیات همۀ بشریت قلم‌داد نموه است. این خود بیان‌گر اهمیت و ضروت تحقیق در خصوص حق حیات انسان را به نمایش می‌گذارد. هدف این پژوهش نیز تبیین و برجسته‌ساختن ارزش انسان ‌در منابع اصلی اسلام بوده است. پرسش‌هایی‌که مطمح نظر بوده، این بوده است که اسلام برای حمایت و حفاظت از حیات بشر، چه اقدامات و راه‌کارهایی را مطرح ساخته است؟ و چرا در جوامع اسلامی به حیات انسان توجه کم‌تری صورت می‌­گیرد؟ حکمت و فلسفۀ قصاص در اسلام بر چه اصلی استوار است؟ این تحقیق ازجمله‌ تحقیقات کتاب‌خانه‌یی است، که به روش تحلیلی – توصیفی، با استفاده از منابع دست‌اول اسلامی تهیه شده است. یافته‌‌های تحقیق نشان می‌­دهند که اسلام به‌صورت کلی و با قاطعیت از انسان و حیات او حمایت نموده و هرنوع تعرض به حیات او را بزرگ‌ترین جنایت بر بشریت و سرکشی از فرامین الهی برشمرده است.
توسعۀ فرهنگی؛ راهی برای کاهش خشونت علیه زنان در افغانستان
Authors:   پوهنمل/ دانش‌یارِ دیپارتمنت حقوق‌، پوهنځی/ دانش‌کدۀ حقوق ‌‌و علوم سیاسی، پوهنتون/ دانش‌گاه غالب، هرات، افغانستان, وحیدی عبدالملک
Published: December 2024

بخش زیادی از عوامل گسترش خشونت علیه زنان در افغانستان، فرهنگی است. چه­ این‌که فرهنگ، هنجار هدایت‌گری است که بر بخش‌های مختلف حیات فردی و اجتماعی انسان اثر می‌گذارد. پرسش این است که نقش توسعۀ فرهنگی در کاهش خشونت علیه زنان چه‌گونه است؟ پاسخ به این پرسش، مهم به نظر می‌­رسد. مقالۀ حاضر که با روش تحلیلی - توصیفی و با استفاده از منابع کتاب‌خانه‌یی انجام شده است، به منظور کاهش خشونت علیه زنان،­ تلاش کرده به پرسش فوق پاسخ بگوید. یافته‌های تحقیق نشان می­‌دهند که توسعۀ فرهنگی، موجب رشد فکری جامعه شده و ظرفیت افراد، به‌خصوص زنان را در مواجهه با وضعیت‌­‌های مخاطره­‌آمیز ارتقا می‌­بخشد. تلاش برای توسعۀ فرهنگی مرتبط به زنان، از قبیل آموزش زنان در معرض خشونت، ایجاد مرکز احصائیه/ آمار قربانیان خشونت، ایجاد فضای امن برای افراد متضرر و آسیب­‌دیده، هم‌کاری دوسویۀ نهادهای صحی و امنیتی در زمینۀ اعلام جرم و ثبت وقایع خشونت­‌آمیز، جبران خسارت از زنان قربانی خشونت، ارائۀ خدمات مشاوره­‌یی به قربانیانِ خشونت، اعتماد به نفس زنان را افزایش داده و توان آن‌ها را در ارائۀ پاسخ مناسب در برابر پدیده‌‌های مجرمانه بهبود می‌­بخشد. در‌نتیجه، رشد فرهنگی، پیش‌گیری رشدمدار از خشونت علیه زنان تحقق یافته و بانوان از آماج ‌جرم‌بودن، رهایی می‌­یابند.
حق حاکمیت دولت بر منابع طبیعی از منظر حقوق بین‌الملل
Authors:   دیپارتمنت‌ حقوق، پوهنځی/ دانش‌کدۀ حقوق و علوم سیاسی، پوهنتون/ دانش‌گاه جامی، هرات، افغانستان, احمدی فضل‌احمد
Published: December 2024

یکی از عمده‌ترین مسائل و در عین حال بحث‌بر‌انگیزترین موضوعات حقوقی، مسألۀ حاکمیت است. حاکمیت علاوه‌بر‌‌این‌که جدال‌برانگیز است، اِعمال آن بر موارد تحت پوشش نیز بحث‌های گسترده‌یی را به هم‌راه دارد؛ از‌این‌رو، یکی از موضوعات و مسائل بسیار مهم و هم‌چنان با ارزشِ حاکمیت، حاکمیت دولت‌ها بر منابع طبیعی می‌باشد. اهمیت این موضوع زمانی بیش‌تر تبارز می‌یابد که دولت‌ها منابع طبیعی را ملّی‌سازی نموده و حاکمیت بر آن‌ها را جزو حقوق ذاتی خویش می‌دانند و تبیین منزلت این ادعا در حقوق بین‌الملل هدفی است، که مورد‌توجه قرار می‌گیرد. با‌توجه به این مطالب، بررسی این‌که مسألۀ حاکمیت بر منابع طبیعی به‌عنوان یک حق طبیعی و ذاتی برای دولت‌ها در حقوق بین‌الملل چه‌گونه است؟ پرسش‌ اساسی این پژوهش را ساخته است. با استفاده از روش توصیفی- تحلیلی و با کمک از منابع کتاب‌خانه‌یی، مسأله مورد کندوکاو قرار گرفته و نتایج آن بیان‌گر آن است که موضوع حق حاکمیت دولت‌ها بر منابع طبیعی در حقوق بین‌الملل مورد توجه قرار گرفته و حکایت از آن دارد، که این حق برای دولت‌های مستقل جای‌گاه حق ذاتی و جدایی‌ناپذیر از حاکمیت را دارد و هم‌چنین منزلت حق حاکمیت بر منابع طبیعی به‌عنوان یک قاعدۀ حقوقی، اگر نگوییم قاعدۀ آمره است، می‌توان آن را از‌جمله قواعد عام‌الشمول حقوق بین‌الملل پنداشت.
Romania
Authors: Horváth Réka ,   Philosophy Documentation Center
Published: December 2024

In this article, the author presents the results of the research conducted in the framework of GSBE 2022–2024 on business ethics education in Romanian universities. The courses tought in universities cover key topics such as: ethics and morality; social responsibility; ethics in new technologies; corruption; human rights. Respondents to the survey identified as important topics for the coming years issues such as: risk related to digitalization; influencing the media; business ethics and artificial intelligence; responsibility of technology companies for the effects of the technologies they bring to market. The research has shown that in the Romanian universities, which appear for the first time in the GSBE analysis, business ethics education is present at both bachelor and master level. There are also local researches that have been published in the world’s leading academic journals.
Investigating Accountants’ Perceptions and Adoption Intentions Towards Artificial Intelligence in Malaysian Public Sector Accounting
Authors: Ali Azwadi , Samsudin Zaira Aniza
Published: December 2024

Purpose: The current study aims to investigate the awareness and potential readiness among accountants in Malaysian governmental departments to adopt artificial intelligence (AI) in anticipation of the implementation of an AI-embedded accounting system.
Design/ Methodology/ Approach: A quantitative online survey was employed to assess the awareness and potential readiness for AI adoption among Malaysian governmental accountants. The unified theory of acceptance and use of technology (UTAUT2), which is a well-established framework in technology acceptance research, guided the conceptualisation of adoption readiness.

Findings: The results demonstrated that accountants had a moderate level of AI awareness as compared to their previous knowledge. Nonetheless, most respondents expressed a high willingness to adopt AI in daily tasks, while only minimal job security concerns regarding the substitution by AI were expressed. The UTAUT2 revealed that only performance expectancy
emerged as a significant predictor of AI usage intention, which posited that Malaysian public sector accountants primarily focused on the perceived benefits when considering adopting AI. Comparatively, other factors, such as effort expectancy and facilitating conditions, played a less prominent role.

Research Limitations/ Implications: The limitations included a relatively low response rate and the sole focus on UTAUT2, which did not incorporate other potential factors explored in different research frameworks.

Practical Implications: Training that emphasises real-world benefits for accountants can assist in bridging the gap between willingness and AI usage in Malaysian public sector accounting, apart from prioritising functionalities that can improve existing workflows. Resultantly, higher accountant confidence and AI adoption are achieved.

Originality/ Value: The findings contributed valuable insights pertinent to the current Malaysian governmental efforts in promoting AI adoption across various sectors.

Keywords: Malaysian public sector accounting, AI adoption, accounting information systems, UTAUT2
Mutual understanding between patient and interpreter is as important as between interpreter and doctor
Authors:   Institute of Health and Care Sciences, Department of Learning and Leadership for Healthcare Professional, University of Gothenburg, Sweden, Fatahi Nabi ,   Psychology Department, Faculty of Arts, Soran University, Soran, Iraq
Published: December 2024

With significant global migration, cross-cultural and cross-lingual clinical encounters are common. Effective communication between patient and physician is essential for patient safety. The diversity in languages and cultures poses challenges for healthcare professionals. It’s important for interpreters to understand patients as well as they understand doctors. Assigning interpreters based on the patient’s mother tongue, rather than citizenship, can help prevent misunderstandings. To reduce misunderstandings in clinical consultations, interpreters should be matched to patients based on their mother tongue. Mutual understanding between patient and interpreter is as crucial as between interpreter and doctor. This approach emphasizes the importance of linguistic and cultural competence in healthcare, ensuring that all parties involved in the communication process can understand each other effectively.
prevalence of needle stick and sharp material injury and associated factors among nurses in arsi zone government hospitals south east Ethiopia.
Authors:   Arsi University College of Health Science Department of Public health, Aredo Melese Tadesse , Gebre Amde Eshete , Obsie Girma Worku ,   Arsi University College of Health Science Department of Public health, Wakuma Samson ,   Addis Ababa University College of Health Science School of Public health
Published: December 2024

Background: Needle-Stick and sharp Injuries are among the hazards and problems that can expose health workers to infections. Hepatitis B, C & HIV are some of biological hazards threatening the health of thousands of healthcare workers. The most common mode of transmission of these diseases is via needle stick and sharp injury.

Objective: To assess magnitude and associated factors of needle stick and sharp injuries among Nurses in Arsi zone health facilities from December 2020 to January 2021.

Methods: An institutional based cross sectional study design was conducted among nurses working in five government hospitals in Arsi Zone, Ethiopia. Participants were selected randomly from each hospital. Data were collected using structured, pretested and customized questionnaires. Multivariate logistic regression models were applied to determine the association between independent and dependent variables.

Result: A total of 303 Nurses participated in this study making the response rate 97.4%. Prevalence of Needle stick/sharp material injury in the past one year among Nurses in government Hospitals in Arsi zone was 42.2%. The highest prevalence of needle stick/sharp material injury 61.8% was recorded in Gobesa district Hospital, while the least prevalence 29.5% was recorded in Abomsa Hospital. Recapping needle after use and number of working hours per week, were some of the risk factors of needle stick and sharp materials injury.
Acute Cardiac Tamponade Following Adult Allogeneic Hematopoietic Transplantation
Authors:   Houston Methodist Hospital, Houston, USA., M.D., Ph.D Yuqi Zhang , Sethi Risha , Gong Zimu , Hinman Breeana , Trachtenberg Barry ,   Houston Methodist Hospital, Houston, USA., May Romelia , Carrum George , Kamble Rammurti ,   Center for Cell and Gene Therapy, Baylor College of Medicine and Houston Methodist Hospital, USA
Published: December 2024

Large pericardial effusions (LPEs) and consequent acute cardiac tamponade (ACT) are rare in adult hematopoietic transplants. Amongst 553 allogeneic hematopoietic transplantation (allo-HCT), a total of 5 (0.9%) developed ACT at <100 days from allo-HCT (days +1, +16, + 22, +60 and day +91). The median time to neutrophilic engraftment was 20 days (range, 12-30). ACT preceded engraftment in 3 patients. ACT manifested as acute, new, or worsening shortness of breath. All 5 patients had no acute GvHD (aGVHD) or CMV reactivation/infection. Pericardial fluid was serous in 2 and serosanguinous in 3 patients. A cumulative total of 1700 ml, 1500 ml, 150 ml, 300 ml, and 800 ml pericardial fluid were removed. Laboratory analysis did not support bacterial or viral etiology and rheumatologic profiles were negative. Histology of pericardial tissue from 2 patients who underwent pericardial window showed benign fibro adipose tissue with reactive mesothelial tissue with fibrous adhesions. There was no evidence for acute inflammatory or infectious processes. We highlight LPE development as a possible severe complication in patients undergoing allo-HCT that requires prompt intervention.
Evaluation Of Renal Biomarkers During Coronavirus-2 Infection Of Severe Acute Respiratory Syndrome
Authors:   Laboratory of Biochemistry and Molecular Biology, Faculty of Medicine, Pharmacy and Odontology, Cheikh Anta Diop University of Dakar, Senegal, A Ndiaye ,   Laboratory of Biochemistry, Aristide Le Dantec Hospital, Senegal, MM Gueye ,   National Hospital Center Cheikh Ahmadoul Khadim, Senagal, A Samba ,   Laboratory of Biology, Abass Ndao Hospital, Senegal, S Thiam ,   Laboratory of Biochemistry, Dalal Djam Hospital, Senegal, IY Soumah ,   Laboratory of Biochemistry and Molecular Biology, Faculty of Medicine, Pharmacy and Odontology, Cheikh Anta Diop University of Dakar, Senegal, F Diedhiou ,   Laboratory of Biochemistry and Molecular Biology, Faculty of Medicine, Pharmacy and Odontology, Cheikh Anta Diop University of Dakar, Senegal, NF Coly ,   UFR health of ThiÃ¨s, Senegal, F Cissé ,   Laboratory of Biochemistry, Dalal Djam Hospital, Senegal, F Diallo ,   Laboratory of Biochemistry, Aristide Le Dantec Hospital, Senegal
Published: December 2024

Introduction : In December 2019, an outbreak of coronavirus disease 2019 (COVID-19) occurred in Wuhan, Hubei Province, China. It quickly spread to other parts of the world. Advances in the field of pathophysiology have shown that co-expression of angiotensin-converting enzyme 2 (ACE 2) receptors and TMPRSS proteases are required for virus entry into the host cell. Direct renal involvement of the virus was therefore strongly suspected due to the high concentration of these receptors at the renal level, particularly at the level of the proximal tubule.

Materials and Method : This was a prospective, descriptive and analytical study of patients infected with SARS-CoV2. For each patient, blood samples were taken on a heparin tube or dry tube for the determination of parameters (albumin, creatinine, urea, Na+ K+) with the Abbott ARCHITECT ci4100.

Results : Our study population consisted of 153 subjects with covid-19. The mean age was 55Â±19 years (15 and 93 years). The most representative age group was patients over 60 years of age (52.3%). Male sex accounted for 53.8% of the study population. 45.1% of patients had a severe form with 16.3% of deaths during hospitalization. The association of renal biomarkers with disease severity showed that the risk of severe disease was higher in patients with hypoalbuminemia (OR=5.3 ; p=0.001), hyperuraemia (OR=4.1; p=0.001), hypercreatinine (OR=3.6; p=0.001), hyponatremia (OR=2.8; p=0.008) and hyperkalemia (OR=2.7; p=0.003).

Conclusion: Disruptions of renal biomarkers during SARS-Cov2 infection increase the risk of severity and mortality. Our study suggests that clinicians should pay close attention to kidney biomarkers in hospitalized patients with COVID-19.
Left Atrial Stiffness Index
Authors:   Clinca San Felipe Lima Peru, Vargas Mario
Published: December 2024

Left atrial stiffness index is a new method to evaluate left atrial function. It¨s calculated by the relation between E/E´ divided by left atrial reservory strain. In this review we evaluate the relationship of these values to the concept of rigidity, the current clinical evidence and the prospects for their clinical use.
Risk Stratification of In-Hospital Mortality in Patients with High-Risk Pulmonary Embolism.
Authors:   V.N. Karazin Kharkiv National University, Kharkiv, Ukraine, V.I Tseluyko , L.M. Yakovleva , N.E. Mishchuk , M.V. Kurinna , L.V. Kharchenko , R.N. Askierov , N.G. Shylo ,   V.N. Karazin Kharkiv National University, Kharkiv, Ukraine
Published: December 2024

Objective. To identify factors associated with in-hospital mortality and to develop and validate a formula for additional risk of early mortality in patients (pts) with high-risk pulmonary embolism (PE).

Materials and Methods. The study consisted of two phases. In Phase I, a retrospective analysis was conducted on the medical records of 113 pts with high-risk PE who were consecutively hospitalized at Kharkiv City Clinical Hospital No. 8 from 01.01. 2017 to 01.01.2023. The mean age of pts was 65.14±14.13 years, with 45 (38.8%) males and 68 (60.2%) females. Based on the course of the disease, the pts were divided into two groups: Group 1 – 63 pts (55.8%) who improved and were discharged, and Group 2 – 50 pts (44.2%) who died during hospitalization. Phase II of the study involved a multicenter cohort (9 centers in Ukraine that provided data on pts with high-risk pulmonary embolism hospitalized from January 2023 to December 2023). This phase included 75 pts with high-risk PE, with mean age of 60.60±13.40 years; 38 (50.7%) were male, and 37 (49.3%) were female. Group I consisted of 65 patients (80%) discharged with improvement, Group II comprised 15 patients (20%) who died during hospitalization. Clinical and anamnestic and laboratory-instrumental data were analyzed, statistical analysis of the resulting figures was performed.

Results and Discussion. In Phase I of the study, a formula for additional risk stratification of early mortality in pts with high-risk PE was developed. Using ROC analysis, the sensitivity of the resulting prognostic formula was found to be 64.0%, and the specificity was 92.1%. Based on this formula, we proposed a simplified scale called SBAFS (S - saturation, B - bifurcation, A - arterial hypotension, F - fraction of ejection, S - female sex). In Phase II of the study, the sensitivity and specificity of the obtained formula were validated using ROC analysis: the sensitivity was 93.3%, and the specificity was 74.6%, confirming the results of Phase I. When evaluating the proposed simplified SBAFS scale, it was also found that in patients of Group II, the mean score on the scale was (2.53±0.83) and was higher than that in Group I: (1.57±0.96), p=0.0006.

Conclusions. The main factors associated with the risk of in-hospital mortality in pts with high-risk PE are decreased oxygen saturation, thrombus localization in the bifurcation of the pulmonary artery as determined by Ð¡Ð¢PA angiography, arterial hypotension, female sex, and decreased left ventricular ejection fraction as assessed by echocardiography. The previously proposed SBAFS formula confirmed its significance upon validation involving data on PE pts from 9 regions of Ukraine, with a sensitivity of 93% and specificity of 75%.
Rejuvenation
Authors:   Professor of Advanced Medicine, President of Cell Sonic Limited, UAE., Hague Andrew
Published: December 2024

CellSonic has been saving lives for many years by curing chronic disease, something that biochemists cannot do. It is now evident that Cell Sonicâ€™s improvement on lives goes further, it makes people biologically younger. This article examines two cases in detail. The ladies are both 59 years old and live on opposite sides of the world.
Mild Inflation Naturally Prevents Divergence of Debt to GDP Ratio
Authors: Tanaka Yasuhito
Published: December 2024

This paper shows mainly the following results. 1) The debt to GDP ratio cannot diverge to infinity, that is, fiscal collapse is impossible. The necessary condition for this result is that the propensity to consume from the asset is positive. 2) The divergence of the debt to GDP ratio is prevented by inflation when the interest rate on government bonds is considerably higher than the real growth rate, and the inflation rate which is sufficient to prevent divergence of the debt to GDP ratio is smaller than the interest rate on government bonds. Only an inflation rate slightly greater than the difference between the interest rate on government bonds and the sum of the real growth rate and the propensity to consume from the asset is required. This inflation is not caused by policy but occurs naturally.
Technical Competency Assessment of Peripheral Blood Smears: Tools and Trends Learned From 2 College of American Pathologists Q-Probes Studies
Authors: Vos Jeffrey A. , Venkataraman Girish , Jiang Liuyan (Jennifer) , Blond Barbara J. , Coulter Suzanne , Souers Rhona J.
Published: December 2024

Context.—

Morphologic evaluation of peripheral blood smears provides valuable information to diagnose and manage a variety of hematologic disorders.

Objective.—

To measure the competency of the technical staff in the morphologic evaluation of peripheral blood smears and provide performance trends.

Design.—

Participating technologists accessed 10 whole slide–imaged peripheral blood smears through a web-based imaging tool in 2 separate studies. Participants performed a 100-cell differential and morphologic evaluation for each slide image. Grading criteria, determined by 3 hematopathologists, were weighted according to their clinical significance (score range, 0–100 for each case). Each institution and participant answered a questionnaire to assess the impact of current practices and educational programs on competency scores.

Results.—

A total of 776 technologists from 92 institutions participated in study 1 and 1495 technologists from 179 institutions participated in study 2. Median performance scores for institutions were 78.9 and 87.6 for studies 1 and 2, respectively, encompassing a range of hematologic disorders. Based on results of the questionnaire for study 1, higher performance scores were seen when institutions required a specific number of continuing education credits per year through an agency (P = .005). In study 2, institutions with remediation procedures following a failed competency demonstrated higher performance scores (P = .03).

Conclusions.—

Medical technologist competency of peripheral blood smears improves with level of experience and is positively impacted through attending educational programs. Whole slide images offer a convenient means of assessing technical competence and provide data to allow institutions to appropriately focus their procedures and educational efforts.
Lacancı Teori Bağlamında Ayna Evresinin Şiir Sanatına Yansıması
Authors: Akoğlu Bahar
Published: December 2024

Bu araştırma sanatçıların eserlerinde arzu nesnesinin eksikliğini ve ayna evresinin izini psikanalitik çerçevede irdelemeyi ve yorumlamayı amaçlamıştır. Çalışmada Necip Fazıl Kısakürek, Şükrü Erbaş, Ahmet Hamdi Tanpınar, Behçet Aysan, Cahit Sıtkı Tarancı, Ümit Yaşar Oğuzcan’ın şiirleri değerlendirildiği için nitel yöntem tercih edilmiştir. Şairlerin eserleri çalışma için doküman olarak toplanmış ve seçilen şiirler Lacancı Teori çerçevesinde değerlendirilmiştir. Çalışmada sonucunda şairlerin psişik yapılarındaki imgelerin dışavurumları, nesne eksikliği, sembolik düzendeki kaygıları analiz edilmiştir. Sanatçının iç dünyasının kendisi tarafından esere yansıtıldığı, Öteki ile kurulan ilişkinin trajik yazgısının sanatla dışavurumunun kaçınılmaz olduğu ortaya koyulmuştur. Şairlerin hem benlik hem de gerçeklik anlayışları her zaman dizelerinde bir ayna arayışında kendini göstermiş, İlk Öteki olan anneye duyulan özlem eserlere yansımıştır. Eksik nesne kendini tamamlamaya çalışmış ve çoğu şairde baba yasası, ölüm ve keder duygusuyla karakterize edilmiştir.
Legal Protection for Consumers in E-commerce Transactions Based on the Consumer Protection Law
Authors: Rojimantoro Fahrur , Sadam Moh , Rahman Alip , Sutrisno Anom
Published: December 2024

Along with the rapid development of e-commerce, consumer protection is a very important issue considering the potential losses that can be experienced by consumers in online transactions. This research aims to analyze legal protection for consumers in e-commerce transactions based on the Consumer Protection Law (UUPK, Undang-Undang Perlindungan Konsumen) in Indonesia. The research method uses a normative approach with juridical analysis of regulations governing consumer rights and obligations, as well as the role of consumer protection institutions such as the National Consumer Protection Agency and the Non-Governmental Consumer Protection Agency (LPKSM, Lembaga Perlindungan Konsumen Swadaya Masyarakat). The results show that although GCPL has regulated various consumer rights, the implementation of consumer protection in the e-commerce sector still faces various challenges, especially the lack of supervision, regulations that are not fully adaptive, and low consumer awareness. This research implies the need to strengthen the role of consumer protection institutions and update regulations so that consumer protection in e-commerce transactions can be more effective.
Tıbbi Nane (Mentha piperita L.) Bitkisinin Fide Gelişim Döneminde Uygulanan Farklı BAP, IBA ve IAA Hormon Dozlarının Büyüme ve Biyokimyasal Parametreler Üzerine Etkileri
Authors: Yolcu Muhammed Said , Öksüz Agah , Güler Emrah , Turan Ferzat
Published: December 2024

Bu çalışma, Mentha piperita L. bitkisinde BAP, IBA ve IAA hormonlarının 50 ve 100 ppm dozlarının büyüme ve biyokimyasal parametreler üzerindeki etkilerini değerlendirmek amacıyla gerçekleştirilmiştir. Araştırma, ‘‘Şansa Bağlı Tesadüf Parselleri’’ desenine göre sera koşullarında üç tekrar ile yapılmıştır. İncelenen parametreler arasında fide ve kök uzunlukları, fide ve kök yaş ile kuru ağırlıkları, toplam fenolik madde miktarı ve antioksidan aktivite (CUPRAC ve FRAP) bulunmaktadır. Çalışma sonucunda; fide kuru ağırlığı dışındaki büyüme parametrelerinde hormon uygulamalarının kontrole göre önemli etkisinin olduğu, fide uzunluk, fide yaş ağırlık ve kök kuru ağırlıklarında en yüksek değerler BAP50 uygulamalarından, kök uzunluğunda en yüksek değer IBA50, kök yaş ağırlığında ise IAA50 uygulamalarında tespit edilmiştir. Uygulanan sentetik biyostimülantların antioksidan aktiviteler ile toplam fenolik madde miktarı üzerine önemli bir etkisinin olmadığı görülmüştür.
IMPLEMENTASI DAN SOSIALISASI APLIKASI DIKA (DETEKSI DINI KEKHUSUSAN ANAK) DI SEKOLAH INKLUSI SEMARANG
Authors: Agustina Menik Tetha , Amaliyah Shofwatun , Pevita Maria Dimitrij Angie , Sumantiawan Dody Indra
Published: December 2024

Pengabdian kepada masyarakat ini dilakukan dengan tujuan untuk mengimplementasikan dan mensosialisasikan aplikasi DIKA (Deteksi Dini Kekhususan Anak) di Sekolah Inklusi SD N Karanganayar Gunung 02. Aplikasi DIKA dirancang untuk membantu guru dan orang tua dalam mendeteksi secara dini kekhususan anak-anak, terutama yang memiliki kebutuhan khusus, sehingga intervensi dan dukungan yang tepat dapat diberikan sejak awal. Implementasi dan sosialisasi dilaksanakan di SD N Karanganyar Gunung 02. Metode pelaksanaan kegiatan pengabdian ini melibatkan pelatihan intensif bagi para guru untuk menggunakan aplikasi DIKA, serta sosialisasi kepada orang tua mengenai pentingnya deteksi dini dan cara penggunaan aplikasi ini. Pendekatan partisipatif digunakan dalam seluruh kegiatan, di mana guru, orang tua, dan pihak sekolah diajak secara aktif berpartisipasi dalam setiap tahap implementasi. Hasil sosialisasi menunjukkan bahwa aplikasi DIKA dapat membantu guru dalam melakukan deteksi dini dengan mudah sehingga guru dapat memberikan pembelajaran yang sesuai dengan kebutuhan anak berkebutuhan khusus. Implikasi terhadap masyarakat dari pelaksanaan Pengabdian kepada masyarakat ini adalah adanya peningkatan pengetahuan tenang penggunaan aplikasi DIKA, kepercayaan diri dalam memberikan metode pembelajaran yang tepat bagi anak berkebutuhan khusus dan memberikan pembelajaran yang efektif bagi anak berkebutuhan khusus di sekolah inklusi.
PEMBERDAYAAN IBU HEBAT DESA KARANGGINTUNG DALAM MENDUKUNG KETAHANAN PANGAN MELALUI BUDIDAYA HORTIKULTURA
Authors: Adisonda Rifqi , Handoko Bayu , Nur Rochman Bagus , Dwi Hirma Windriyati Ratna , Anggraeni Gita
Published: December 2024

Ketahanan pangan merupakan kondisi terpenuhinya kebutuhan pangan bagi rumah tangga dengan tersedianya pangan secara cukup, baik dari jumlah maupun kualitasnya, aman, merata dan terjangkau. Upaya mewujudkan ketahanan pangan nasional harus bertumpu pada sumber daya pangan lokal yang mengandung keragamaan antar daerah. Pelaksanaan kegiatan pemberdayaan masyarakat ini di kelompok Ibu Hebat Desa Karanggintung Kecamatan Sumbang Kabupaten banyumas. Tujuan dari kegiatan pemberdayaan ini yaitu 1). Meningkatkan keterampilan dan pengetahuan ibu-ibu dalam bertani dan mengelola budidaya hortikultura, termasuk penggunaan teknologi pertanian yang ramah lingkungan dan berkelanjutan; 2). Dapat menghasilkan produk hortikultura yang dapat dijual atau dikonsumsi sendiri, sehingga membantu meningkatkan pendapatan keluarga dan mendukung ekonomi desa. Metode dalam pelaksanaan Pengabdian Kepada Masyarakat (PKM) adalah memberikan penyuluhan mengenai ketahanan pangan dan budidaya hortikultura, dan dilanjutkan dengan praktik budidaya tanaman sayuran. Hasil dari kegiatan pemberdayaan ini adalah meningkatnya pengetahuan dan wawasan peserta PKM terkait pentingnya menjaga ketahanan pangan dan budiaya tanaman hortikultura, serta menghasilkan produk hortikultura yang dapat dijual atau dikonsumsi sendiri, sehingga membantu meningkatkan pendapatan keluarga dan mendukung ekonomi desa.
PELATIHAN MANAJEMEN ORGANISASI UNTUK MENINGKATKAN PERAN PEMUDA DALAM BERWIRAUSAHA
Authors: Hernany Devia Hetty , Puspita Amelia , Setiawan M. Rizki Putra
Published: December 2024

Pengabdian Kepada Masyarakat ini berjudul Pelatihan Manajemen Organisasi Untuk Meningkatkan Peran Pemuda dalam Berwirausaha di SMKN 2 Banjarmasin. Tujuan dilaksanakannya kegiatan pengabdian masyarakat adalah untuk memberikan penyuluhan serta tanya jawab akan arti pentingnya meningkatkan kualitas serta peran serta pemuda dalam berusaha di tengah masyarakat. Pemuda sangat dituntut beradaptasi dengan cepat dalam mengahadapi perubahan yang terjadi dalam masyrakat untuk dapat terus berdaptasi. Metode kegiatan pengabdian kepada masyarakat ini berlangsung pada bulan November 2024 dan terdiri dari tiga tahapan kegiatan. Tahapan pertama yaitu tahap persiapan dalam melakukan survey lokasi mitra, peserta kegiatan dan penyusunan materi. Tahap kedua yaitu pelaksanaan yang meliputi pemberian ceramah materi Pelatihan Manajemen Organisasi Untuk Meningkatkan Peran Pemuda dalam berwirausaha Di SMKN 2 Banjarmasin. Tahap ketiga yaitu evaluasi antara lain untuk mengetahui seberapa dalam pemahaman peserta pelatihan terhadap materi yang diberikan. Kesimpulan dari kegiatan pengabdian masyarakat ini adalah para generasi muda di SMKN 2 Banjarmasin antusias dalam menerima ilmu baru dan aktif melakukan tanya jawab mengenai bagaimana cara mengimplementasikan Manajemen Organisasi Untuk Meningkatkan Peran Pemuda dalam Berwirausaha.
The Sound of Mormonism: A Media History of Latter-day Saints
Authors: Farmer Jared
Published: December 2024

This book examines the history and influence of the Church of Jesus Christ of Latter-day Saints through its music and media. From hymns to the Mormon Tabernacle Choir, it explores how sound shaped Mormon identity and public perception.
Encouragement of Entrepreneurship in Management of Preschool Learning Environment: Science Education Practices
Authors: Mutlu Ayfer
Published: December 2024

Entrepreneurial characteristics are among the characteristics individuals should have in our century. Although there is an awareness of the necessity of gaining entrepreneurial characteristics at all levels of education, unfortunately, the number of studies focusing on entrepreneurship education at the preschool level is limited. For this reason, this chapter focuses on the promotion of entrepreneurship in preschool science education and it aims to draw attention to entrepreneurship education at the preschool level, the use of science activities in preschool entrepreneurship education, and guide researchers who want to work in this field and the preschool teachers who want to give entrepreneurship education. For this purpose, in this chapter, a basic framework was established for entrepreneurship education at the preschool level, and the role of science activities in preschool entrepreneurship education and the development of effective entrepreneurial preschool science activities was expressed through a non-systematic literature review. In addition, three different practical entrepreneurial preschool science activities developed by the author were introduced and suggestions were made to apply them in preschool classes.
Turizmde Gerçeklik Teknolojisi
Authors: Torun Nur Kuban , Torun Tolga
Published: December 2024

Teknolojideki gelişmeler birçok sektörde kendini göstermeye başlamıştır. Özellikle insan ile ilişkilerin ön saflarda olduğu ve deneyime dayalı sektörler, teknolojinin sağladığı kolaylıkları kendilerine adapte etmeye başlamıştır. Bilişim alanında yapılan çalışmalar, gerçeklik algısını değiştirecek boyutta yenilikler getirmiştir. Bu yeniliklerden birisi de gerçeklik teknolojileri olarak yerini almaktadır. Gerçeklik teknolojileri bileşenleri olarak gerçek dünya içerisine sanal nesneler yerleştirmeye yarayan arttırılmış gerçeklik (AR), fiziksel dünyadan bağımsız bir şekilde kendi kuralları ve işleyişi olan sanal gerçeklik (VR), fiziksel dünya ile sanal dünyanın birleşimi olan karma gerçeklik (MR) ve tüm bu bileşenlerin hepsinin bir çatı altında toplandığı şemsiye terim genişletilmiş gerçeklik (XR) uygulayıcıların karşısına çıkmaktadır. Her ne kadar bu teknolojiler maliyet, enerji verimliliği ve görsel kalitesi gibi konularda bir gelişim evresi geçirse degerçeklik uygulamaları turizm sektöründe bilgi verici, eğitici, deneyim yaratıcı ve eğlencenin boyutunu arttırıcı bir yapı ile kullanılmaya başlanmıştır. Özellikle turizm önünde oluşabilecek engelleri aşmada büyük bir avantaj yaratan bu teknolojiler, gelecekte yapay zekânın da devreye girmesi ile birlikte daha etkin bir şekilde kullanılabilecektir.
Dijital Pazarlama
Authors: Sönmez Karapınar Ebru
Published: December 2024

Bu bölümde dijital pazarlama stratejilerinin kapsamını anlamak ve turizm işletmelerinin rekabetçi ve dijital odaklı bir dünyada müşterilerinin değişen ihtiyaçlarını etkili bir şekilde karşılayabilmelerini sağlamak için kapsamlı bir çerçeve sunulmuştur. Bu kapsamda dijital ve rekabetçi ortamda turizm sektöründe faaliyet gösteren işletmelerin daha etkileşimli hizmet sunumunda dikkate alması gereken makro ve mikro çevre faktörleri ve bu alanda gelişim gösteren yeni trendler ile dijital pazarlama karmasını oluşturan 9P (ürün, fiyat, dağıtım, tutundurma, insan, özellikler, süreç, kişiselleştirme, tahmin) incelenmiştir.
Turizmde Dijital İkiz Teknolojisi
Authors: Yılmaz Uz Canan , Arslan Seda
Published: December 2024

Teknolojik ilerlemeler, özellikle Endüstri 4.0'dan Endüstri 5.0'a geçişin hızlanmasına katkıda bulunan dijital ikiz teknolojisinin daha geniş bir uygulama alanına yayılmasına olanak sağlamıştır. Dijital ikiz, gerçek dünyadaki bir nesne, süreç veya sistemin yüksek doğrulukla sanal bir modelinin oluşturulmasını ve bu modelin gerçek zamanlı verilerle simülasyon yoluyla geri bildirim sağlamasını ifade eden bir teknolojidir. Bu teknoloji, operasyonel verimliliği artırarak daha doğru ve etkili kararlar alınmasına imkân tanımaktadır. Dijital ikizin temel işlevi, fiziksel bir modelin özelliklerini sanal ortamda birebir yansıtmak ve çift yönlü iletişim aracılığıyla dinamik karar alma süreçlerine destek olmaktır. Turizm endüstrisi de dijitalleşme süreciyle önemli bir dönüşüm yaşamaktadır. Dijital ikiz teknolojisi, turizm sektöründe gerçek zamanlı deneyimler sunarak sektördeki akıllı çözümleri güçlendirmekte ve operasyonel etkinliği artırmaktadır. Bu teknoloji, özellikle veri odaklı karar alma mekanizmalarının güçlendirilmesinde ve böylece turizmde rekabetçi avantaj sağlanmasında kritik bir rol oynamaktadır. Dijital ikiz teknolojisi, bilgi teknolojileri ve uygulamalarındaki hızlı gelişmeler ışığında turizm endüstrisinin daha verimli, dinamik ve yenilikçi bir hale gelmesine önemli ölçüde katkıda bulunmaktadır.
Bu bölümde turizmde dijital ikiz teknolojisi kavramsal bir çerçevede ele alınmıştır. Dijital ikiz teknolojisi, gerçek dünyadaki nesne, süreç ve sistemlerin sanal ortamda yüksek doğrulukla modellenmesi ve bu modellerin gerçek zamanlı verilerle simüle edilmesiyle operasyonel verimliliği artırmakta, daha doğru kararların alınmasını sağlamaktadır. Bu teknoloji, turizm endüstrisinde sadece verimliliği artırmakla kalmayıp, aynı zamanda yenilikçi çözümlerin geliştirilmesine de olanak tanımaktadır. Sonuç olarak, dijital ikizlerin turizm sektöründeki dijital dönüşüm sürecini hızlandırarak, gelecekte bu alanda önemli bir rol oynamaya devam edeceği öngörülmektedir.