bluuebunny/crossref_metadata_2025 huggingface dataset:
SSA Translation Is an Abstract Interpretation
Authors: Lemerre Matthieu
Published: January 2023

Static single assignment (SSA) form is a popular intermediate representation that helps implement useful static analyses, including global value numbering (GVN), sparse dataflow analyses, or SMT-based abstract interpretation or model checking. However, the precision of the SSA translation itself depends on static analyses, and a priori static analysis is even indispensable in the case of low-level input languages like machine code.

To solve this chicken-and-egg problem, we propose to turn the SSA translation into a standard static analysis based on abstract interpretation. This allows the SSA translation to be combined with other static analyses in a single pass, taking advantage of the fact that it is more precise to combine analyses than applying passes in sequence.

We illustrate the practicality of these results by writing a simple dataflow analysis that performs SSA translation, optimistic global value numbering, sparse conditional constant propagation, and loop-invariant code motion in a single small pass; and by presenting a multi-language static analyzer for both C and machine code that uses the SSA abstract domain as its main intermediate representation.
Probabilistic Resource-Aware Session Types
Authors: Das Ankush , Wang Di , Hoffmann Jan
Published: January 2023

Session types guarantee that message-passing processes adhere to predefined communication protocols.
Prior work on session types has focused on deterministic languages but many message-passing systems, such as Markov chains and randomized distributed algorithms, are probabilistic.
To implement and analyze such systems, this article develops the meta theory of probabilistic session types with an application focus on automatic expected resource analysis.
Probabilistic session types describe probability distributions over messages and are a conservative extension of intuitionistic (binary) session types.
To send on a probabilistic channel, processes have to utilize internal randomness from a probabilistic branching or external randomness from receiving on a probabilistic channel.
The analysis for expected resource bounds is smoothly integrated with the type system and is a variant of automatic amortized resource analysis.
Type inference relies on linear constraint solving to automatically derive symbolic bounds for various cost metrics.
The technical contributions include the meta theory that is based on a novel nested multiverse semantics and a type-reconstruction algorithm that allows flexible mixing of different sources of randomness without burdening the programmer with complex type annotations.
The type system has been implemented in the language NomosPro with linear-time type checking.
Experiments demonstrate that NomosPro is applicable in different domains such as cost analysis of randomized distributed algorithms, analysis of Markov chains, probabilistic analysis of amortized data structures and digital contracts.
NomosPro is also shown to be scalable by (i) implementing two broadcast and a bounded retransmission protocol where messages are dropped with a fixed probability, and (ii) verifying the limiting distribution of a Markov chain with 64 states and 420 transitions.
Impredicative Observational Equality
Authors: Pujet Loïc , Tabareau Nicolas
Published: January 2023

In dependent type theory, impredicativity is a powerful logical principle that allows the definition of propositions that quantify over arbitrarily large types, potentially resulting in self-referential propositions. Impredicativity can provide a system with increased logical strength and flexibility, but in counterpart it comes with multiple incompatibility results. In particular, Abel and Coquand showed that adding definitional uniqueness of identity proofs (UIP) to the main proof assistants that support impredicative propositions (Coq and Lean) breaks the normalization procedure, and thus the type-checking algorithm. However, it was not known whether this stems from a fundamental incompatibility between UIP and impredicativity or if a more suitable algorithm could decide type-checking for a type theory that supports both. In this paper, we design a theory that handles both UIP and impredicativity by extending the recently introduced observational type theory TTobs with an impredicative universe of definitionally proof-irrelevant types, as initially proposed in the seminal work on observational equality of Altenkirch et al. We prove decidability of conversion for the resulting system, that we call CCobs, by harnessing proof-irrelevance to avoid computing with impredicative proof terms. Additionally, we prove normalization for CCobs in plain Martin-Löf type theory, thereby showing that adding proof-irrelevant impredicativity does not increase the computational content of the theory.
Urban Ecological Planning Model Based on Information Entropy and Meteorological Suitability Evaluation Algorithm
Authors: Xu Qiushi
Published: January 2023

In order to improve the effect of regional urban ecological planning and ecological restoration, aiming at the problem of low accuracy of ecological planning and poor matching with the current situation, taking Yucheng County, Shangqiu City, Henan Province as an example, an urban ecological planning model based on information entropy and meteorological suitability evaluation algorithm is designed. The geographical environment of Yucheng County, Shangqiu City, Henan Province is analyzed. Based on the current situation of regional ecological environment, the meteorological suitability evaluation algorithm is introduced to establish the urban ecological planning model. Comprehensively considering land planning factors and meteorological factors, calculate the information entropy of each influencing factor, determine the weight, and optimize the ecological planning model. The experimental results show that this method has achieved good results in the accuracy of ecological planning and the matching degree of the current situation in the urban ecological planning of Yucheng County, Shangqiu City, Henan Province.
Quantum-Dot Cellular Automata-Based Full Adder Design: Comprehensive Review and Performance Comparison
Authors: Joy Upal Barua , Chakraborty Shourov , Islam Sharnali , Zaman Hasan U. , Hasan Mehedi
Published: January 2023

Being one of the promising techniques for future computing systems, quantum-dot cellular automata (QCA)-based circuit design has gained massive interest among researchers due to which numerous QCA-based full adder (FA) circuits have been designed. Due to numerous QCA FA circuits available in the existing literature, researchers find it difficult to invest the time to search, implement, simulate, and analyze QCA FAs to find the best-suited design according to their needs. Existing review articles do not present a complete overview and performance comparison of QCA FAs. Also, the existing articles do not include quite a number of QCA FA designs in the literature review. As a result, a detailed review including all possible QCA FAs becomes essential. Therefore, rather than going for a new QCA FA design, this research aims to aid researchers by providing an extensive literature review and comprehensive study on existing QCA FAs. A total of 47 QCA FAs have been considered for analysis. The QCA FA implementation method and performance parameters are summarized in a tabular manner to provide a quick overview and comparison of the QCA FAs.
A Case of Feline Leishmaniosis with Panniculitis
Authors: Matralis Dimitrios , Papadogiannaki Ioanna , Gkerdidani Evi , Patsoula Eleni , Tegos Nikolaos , Papadogiannakis Emmanouil
Published: January 2023

Leishmaniases are a group of diseases caused by protozoa of the genus Leishmania and transmitted mainly by the bite of sand fly vectors. Cats are infected with at least 6 species of Leishmania. Significant associations have been found between feline leishmaniosis and coinfections mainly with FIV and/or FeLV. A 7-year-old castrated male, domestic short-haired cat was presented with unknown history and cutaneous and ocular lesions. A raised, semifirm swelling on the forehead was observed along with periocular hypotrichosis and conjunctival and third eyelid edema. The indications for pursuing a diagnosis of leishmaniosis are variable, and differing presentations may require the use of different tests. Diagnosis of feline leishmaniosis with panniculitis caused by Leishmania infantum was made by cytology, histopathology, and PCR and Leishmania antibodies (IFA). The cat responded to therapy with meglumine antimoniate and allopurinol.
Pesticide Utilization, Practices, and Their Effect on Honeybees in North Gonder, Amhara Region, Ethiopia
Authors: Teshome Zewdie Abay , Argaw Amssalu Bezabeh , Wanore Walellign Wotro
Published: January 2023

The use of pesticides is increasing from time to time due to their significant importance in maximizing crop production. This situation raised concerns about their potentially adverse effects on honeybee health and the environment, particularly in countries where regulations are not strictly implemented and farmers’ knowledge of safe handling procedures is inadequate. This study was conducted in Chilga district, North Gonder, to assess utilization, types, and supply routes of pesticides. Quantitative and qualitative data were collected using semistructured questionnaires, key informant interviews, and focus group discussions. A multistage sampling technique was used to select 353 respondents (155 beekeepers and 198 nonbeekeepers), and a semistructured questionnaire was administered to the selected respondents. The result indicated a rapid increment in pesticide use regardless of its recent introduction to the district. Out of the ten different kinds of pesticides being used in the study area (2,4-D, diazinon 60%, glycel 41%, diazinon 60%, DDT, a mixture of 2-4-D with glycel, mancozeb 80%, malathion 50%, endosulfan 35%, agrothoate 40%, and ethiosulfane 10%), 2,4-dichlorophenoxyacetic acid, glycel, diazinon, and endosulfan 35% are the most widely used ones. Most of the farmers access these pesticides from illegal traders. About 71.3% of the respondents had no access to advice, and 86.9% of them had no training on how to apply pesticides safely to themselves, to the honeybees, and to the environment. The respondents keep extra pesticides at home and use empty pesticide containers for storing food items. In general, integrated efforts are needed to make farmers in Chilga district aware of their knowledge gap on the safe handling and utilization of pesticides.
Adult Low-Hypodiploid Acute Lymphoblastic Leukemia Emerges from PreleukemicTP53-Mutant Clonal Hematopoiesis
Authors: Kim Rathana , Bergugnat Hugo , Larcher Lise , Duchmann Matthieu , Passet Marie , Gachet Stéphanie , Cuccuini Wendy , Lafage-Pochitaloff Marina , Pastoret Cédric , Grardel Nathalie , Asnafi Vahid , Schäfer Beat W. , Delabesse Eric , Itzykson Raphaël , Adès Lionel , Hicheri Yosr , Chalandon Yves , Graux Carlos , Chevallier Patrice , Hunault Mathilde , Leguay Thibaut , Huguet Françoise , Lhéritier Véronique , Dombret Hervé , Soulier Jean , Rousselot Philippe , Boissel Nicolas , Clappier Emmanuelle
Published: January 2023

Low hypodiploidy defines a rare subtype of B-cell acute lymphoblastic leukemia (B-ALL) with a dismal outcome. To investigate the genomic basis of low-hypodiploid ALL (LH-ALL) in adults, we analyzed copy-number aberrations, loss of heterozygosity, mutations, and cytogenetics data in a prospective cohort of Philadelphia (Ph)-negative B-ALL patients (n = 591, ages 18–84 years), allowing us to identify 80 LH-ALL cases (14%). Genomic analysis was critical for evidencing low hypodiploidy in many cases missed by cytogenetics. The proportion of LH-ALL within Ph-negative B-ALL dramatically increased with age, from 3% in the youngest patients (under 40 years old) to 32% in the oldest (over 55 years old). Somatic TP53 biallelic inactivation was the hallmark of adult LH-ALL, present in virtually all cases (98%). Strikingly, we detected TP53 mutations in posttreatment remission samples in 34% of patients. Single-cell proteogenomics of diagnosis and remission bone marrow samples evidenced a preleukemic, multilineage, TP53-mutant clone, reminiscent of age-related clonal hematopoiesis.

Significance:

We show that low-hypodiploid ALL is a frequent entity within B-ALL in older adults, relying on somatic TP53 biallelic alteration. Our study unveils a link between aging and low-hypodiploid ALL, with TP53-mutant clonal hematopoiesis representing a preleukemic reservoir that can give rise to aneuploidy and B-ALL.

See related commentary by Saiki and Ogawa, p. 102.

This article is highlighted in the In This Issue feature, p. 101
Increasing Biomarker Guidance in the Treatment of Urothelial Carcinoma: Systematic Review of International Clinical Trials
Authors: Bolenz Christian , Kunath Frank , Zengerling Friedemann , Wezel Felix , Schmidt Stefanie , Hartmann Arndt , Eckstein Markus
Published: January 2023

Purpose: Precision oncology requires biomarker testing from tumor tissue for clinical decision-making and selection of targeted therapies. We systematically evaluated the role of tissue biomarker testing within interventional clinical trials for locally advanced and metastatic urothelial carcinoma (UC). Methods: A systematic search within the publicly available ClinicalTrials.gov database was performed for the period 1995 to January 2020. We searched for all interventional studies on systemic treatments for advanced UC. Two investigators independently screened the records and extracted the data for statistical analyses. Results: We included 356 studies out of 827 initial records in the final analysis. The overall number of interventional trials in UC patients significantly increased during the past 25 years. Forty-three studies (12.1%) required specific biomarker testing as a prerequisite for inclusion. Of the remaining 313 trials, explorative biomarkers of interest were studied in 83 studies (23.3%). In trials with obligate biomarker testing as a precondition for study inclusion, only 3 studies (7%) required an actual fresh pretreatment biopsy, while the majority of studies did not state any tissue requirements (55.8%) or accepted archival tissue samples (37.3%). Among studies without biomarker prerequisites, freshly obtained tissue samples were required in 16.3% of studies evaluating immune checkpoint inhibition and 5.7% evaluating targeted therapy. The collection of archival tissue was allowed in 67.4% and 20% of studies evaluating immune checkpoint inhibitors and targeted therapies, respectively. Conclusion: There has been an increase in the number of studies using biomarker-guided interventions for the treatment of advanced UC over the past 25 years. Studies investigating druggable targets in actual UC biopsies immediately before treatment are still rare. Standardized criteria for tissue-based biomarker testing may further accelerate personalized treatment of patients with advanced UC.
Expression Analyses of Rich2/Arhgap44, a Rho Family GTPase-Activating Protein, during Mouse Brain Development
Authors: Goto Naoki , Nishikawa Masashi , Ito Hidenori , Noda Mariko , Hamada Nanako , Tabata Hidenori , Kinoshita Makoto , Nagata Koh-ichi
Published: January 2023

Rho family small GTPases, such as Rho, Rac, and Cdc42, play essential roles during brain development, by regulating cellular signaling and actin cytoskeletal reorganization. Rich2/Arhgap44, a Rac- and Cdc42-specific GTPase-activating protein, has been reported to be a key regulator for dendritic spine morphology and synaptic function. Given the essential roles of Rac and Cdc42 in brain development, Rich2 is supposed to take part in brain development. However, not only the molecular mechanism involved but also the expression profile of Rich2 during neurodevelopment has not yet been elucidated. In this study, we carried out expression analyses of Rich2 by focusing on mouse brain development. In immunoblotting, Rich2 exhibited a tissue-dependent expression profile in the young adult mouse, and the expression was increased during brain development. In immunohistochemical analyses, Rich2 was observed in the cytoplasm of cortical neurons at postnatal day (P) 0 and then came to be enriched in the nucleus with moderate distribution in neuropils at P7. Later at P30, a complex immunostaining pattern of Rich2 was observed; Rich2 was distributed in the nucleus, cytoplasm, and neuropils in many cortical neurons, whereas other neurons frequently displayed little expression. In the hippocampus at P7, Rich2 was distributed mainly in the cytoplasm of excitatory neurons in the cornu ammonis regions, while it was moderately detected in the nucleus in the dentate granule cells. Notably, Rich2 was distributed in excitatory synapses of the cornu ammonis 1 region at P30. Biochemical fractionation analyses also detected Rich2 in the postsynaptic density. Taken together, Rich2 is found to be expressed in the central nervous system in a developmental stage-dependent manner and may be involved in synapse formation/maintenance in cortical neurons.
Teatro latino-americano em tempos de pandemia: festivais internacionais e cruzamentos estéticos
Authors: Borges Luiz Paixão Lima
Published: January 2023

A presença do público é parte constitutiva e essencial para a realização do fenômeno teatral, porém, diante das terríveis repercussões da pandemia da Covid-19 foram estabelecidos protocolos impositivos ao isolamento social, o que impediu as apresentações teatrais presenciais, alterando significativamente as relações entre teatro e público; os artistas cênicos foram impelidos a buscar novas formas de comunicação, no intuito de manter viva sua relação com o público, dentre elas, se destaca a realização de festivais de teatro na modalidade virtual, que possibilitaram encontros de artistas cênicos do Brasil e dos países hispano-americanos e caribenhos. Após uma análise inicial sobre a relação que se constrói entre o palco e a plateia, o artigo pretende analisar a realização virtual de festivais de teatro latino-americanos como proposta de enfrentamento à pandemia e de reorganização do teatro, no momento de maior aflição da população mundial. Com o recorte que limita o período entre junho de 2020 e outubro de 2021, serão apresentados e analisados Convocatórias, Cartas-convite e o Manifesto produzidos pela organização de diversos festivais internacionais latino-americanos de teatro. Foi realizado um estudo comparativo dos documentos, visando compreender os diversos posicionamentos em relação à pandemia. Neste sentido, foi identificada uma confluência em torno da necessidade de afirmação da arte, e particularmente do teatro, como instante de reflexão, resistência e união dos artistas e técnicos naquele momento profundamente adverso.
Participação política de mulheres indígenas no Equador: da Revolução cidadã à pandemia de Covid-19
Authors: Ferreira Ana Luísa Melo
Published: January 2023

Este trabalho tem como objetivo traçar um percurso histórico de participação das mulheres indígenas no Equador entre os anos 2008 a 2020, período que compreende a criação da nova Constituição equatoriana (2008), o levantamento de outubro (2019) e a crise da pandemia de COVID-19 (2020 - presente). Para analisar qual o papel do ativismo de mulheres indígenas equatorianas nesses momentos importantes para o país, fizemos uma revisão detalhada da bibliografia já existente, bem como utilizamos informações disponíveis em meios de comunicação, especialmente em jornais nacionais. Assim, pudemos observar como elas se organizaram frente aos obstáculos de sexo, raça e classe acentuados em momentos extremos como os de crise.
Economia Criativa nos países do Mercosul: breve análise conjuntural
Authors: Moraes Isaías Albertin de , Aguiar Mônica Heinzelmann Portella de
Published: January 2023

O presente artigo tem como objetivo pesquisar a situação do setor de Indústria Criativa nos países membros do Mercado Comum do Sul (Mercosul) no período que vai de 2012 a 2015. No que tange à metodologia, optou-se pela análise crítica de dados bibliográficos e documentais, trabalhando com estatísticas coletadas na UNCTAD, BID e FIRJAN e conceitos de Economia Criativa (EC) elaborados por autores renomados como Howkins, Florida e Throsby. O trabalho está dividido em duas partes:  na primeira, apresenta-se a evolução operacional do conceito de EC e, na segunda, examinam-se os dados referentes ao setor da EC no Mercosul. A conclusão, comparando com outros países do mundo, é de que a EC é uma alternativa promissora de desenvolvimento econômico, porém ainda pouco explorada pelo Mercosul.
Política externa brasileira e transferência internacional de políticas públicas: a Minustah como janela de oportunidade para a cooperação brasileira no Haiti (2004-2017)
Authors: Gallo Rodrigo Fernando
Published: January 2023

O objetivo deste artigo é analisar o uso das políticas públicas sociais brasileiras como recurso da política externa brasileira aplicada ao contexto paralelo à Minustah (2004-2017), de modo a compreender como a agenda doméstica pode ser articulada para a lógica de cooperação internacional para promover desenvolvimento econômico e social. A hipótese é que o Estado brasileiro utilizou a janela de oportunidades aberta pela Minustah para estreitar as relações com o Haiti e transferir políticas públicas sociais para o país caribenho como forma de demonstrar capacidade de lidar com as causas primárias que normalmente geram os conflitos, tais como a pobreza e a miséria – experiência de política externa que transformou o Haiti em um dos principais destinos da cooperação brasileira à época, o que demonstra um modo particular de o Brasil lidar com operações de paz das Nações Unidas. A pesquisa utilizou o método de process tracing para mapear o fenômeno, associado às metodologias de estudo de caso e análise documental, além da técnica de entrevista discursiva semiestruturada.
Princípios de uma Narrativa Transmídia: na Produção da série Heartstopper
Authors: Augusto Ryan , Goes Beatriz Silva
Published: January 2023

O presente artigo trata dos princípios de uma Narrativa transmídia: na Produção da série Heartstopper. Como objetivo vamos identificar as técnicas de uma Narrativa transmídiatica, tendo como foco principal a produção Heartstopper da produtora e escritora Alice Oseman, tendo em vista que a série televisiva é uma das produções midiáticas com maior índice de popularidade nos streamings da atualidade. Para isso, utilizaremos os princípios de uma narrativa transmídia de JENKINS (2008). Nesse sentido, por meio de um estudo descritivo busca-se mostrar os principais princípios para uma produção ser considerada transmídia. Conclui-se que a narrativa da série Heartstopper carrega consigo temas e discussões da atualidade como a aceitação da sexualidade entre os jovens é a questão da homofobia em forma de bullying, que e em diversas cenas é demonstrado como isso afeta pessoas LGBTQ+ e se torna um assunto de suma importância na atualidade.
A representação do jornalista na série norte-americana The Morning Show: uma análise de acordo com o Ethos jornalístico
Authors: Santos Carlos Roberto Praxedes , Kohler Gabrieli Giani
Published: January 2023

Este trabalho examina de que forma as produções audiovisuais retratam a profissão do jornalista a partir da série televisiva norte-americana The Morning Show. A análise foi dividida em cinco categorias: a representação dos jornalistas de acordo com o Ethos jornalístico, o embate entre jornalismo e interesses comerciais evidenciados pela emissora fictícia, compreensão dos quadros de sentido fornecidos pela ficção sobre os jornalistas e a profissão, a representação da disparidade ética entre jornalistas da TV e do jornal impresso e o machismo retratado na série. O artigo confirma que o seriado influencia o público na reflexão sobre o descrédito atual da profissão e corrobora com a representação sobre a disparidade ética e intelectual acerca dos personagens jornalistas do meio impresso e televisivo.
Uma aventura intelectual insurgente
Authors: Maldonado Alberto Efendy
Published: January 2023

Este texto apresenta uma autobiografia intelectual sintética vinculada ao processo de formação, investigação e trabalho do autor na Escola de Comunicações e Artes da Universidade de São Paulo durante a década de 1990. A narrativa dessa trajetória intelectual segue uma linha de exposição historiográfica que pretende relacionar processos epistemológicos com aspectos cruciais da vida sociopolítica e cultural do pensador. Apresentam-se, também, contextos históricos decisivos para a estruturação gnosiológica, teórica e metodológica do pesquisador.
Da publicidade aos estudos sobre cultura do consumo: O longo e produtivo processo de criação de uma teoria compartilhada
Authors: Hellín Pedro
Published: January 2023

Este texto tem como objetivo sintetizar a relação formada no Programa de Pós-Graduação em Ciências da Comunicação da Universidade de São Paulo com os professores Clotilde Pérez e Eneus Trindade há mais de quinze anos, quando movidos pela mútua curiosidade de pesquisa, pela certeza partilhada sobre a necessidade de ampliar o campo de estudo da publicidade, foi estabelecida uma relação profissional e humana que se desenvolveu ao longo desses anos, na qual a nossa forma de compreender e abordar o fenómeno publicitário se consolidou como interdisciplinar, exploratória e colaborativa, gerando ideias que transcendem o estudo do fenômeno publicitário para abranger a cultura do consumo.
50 años de estudios sobre Comunicación. Trayectorias académicas cruzadas
Authors: Navarro Raúl Fuentes
Published: January 2023

En este texto se despliega un ejercicio autorreflexivo del autor acerca de su propia trayectoria como profesor universitario e investigador académico en el campo de estudios de la comunicación durante las cinco décadas más recientes. El punto de partida es la convicción de que es imposible aislar una trayectoria individual, puesto que la historia implica reconocer los cruces mutuamente determinantes con otros individuos y con marcos institucionales de diversas escalas. Toda autobiografía académica es necesariamente una reconstrucción de los vínculos colectivos con pares y con contextos institucionales situados en tiempos y espacios concretos, en este caso ubicados en América Latina, sobre todo en México y en Brasil.
Irradiações intelectuais: Uma década de colaboração com o programa de pós-graduação em ciências da comunicação da universidade de São Paulo
Authors: Contreras Fernando
Published: January 2023

Neste artigo apresentamos uma síntese de colaboração com a Escola de Comunicações e Artes da Universidade de São Paulo (ECA-USP) ao longo de uma década em pesquisa de Comunicação. Nossa contribuição sempre teve origem epistêmica em estudos sobre cultura visual, e apresentamos nossos achados em formato interdisciplinar. Entre os temas mais relevantes, há as noções de irradiação semiótica, publicismo e a contribuição de estudos visuais no conhecimento do fenômeno do acolhimento da publicidade. Destacamos nas conclusões a importância de emoções, sentimentos e sensações sensoriais nos fenômenos atuais da comunicação. O corpo é o artefato da pós-modernidade para fundir história, indústria, publicidade e política através da expressão dos desejos humanos nos discursos da mídia.
Caminhos e intercâmbios na pesquisa em comunicação: Uma trajetória luso-brasileira
Authors: Ferin Isabel
Published: January 2023

Neste texto, procuro traçar e analisar cerca de 30 anos de uma trajetória pessoal de pesquisa, balizada por contextos geográficos, políticos e sociais no espaço da lusofonia e no âmbito das Ciências da Comunicação. O caminho fez-se de encontros e desencontros pessoais, profissionais e institucionais, onde a Escola de Comunicações e Artes e o Programa de Pós-Graduação em Ciências da Comunicação da Universidade de São Paulo adquiriram grande centralidade. Muitas das referências são memórias pautadas por marcos temporais e, como tal, apresentam, à partida, uma reconfiguração do real, onde o viés do tempo, da espacialidade e da nostalgia geracional adquirem relevância significante. O texto configura-se como um ensaio e adota-se uma ordem cronológia na exposição, com vista a explicitar muitas das opções temáticas, teórico-conceituais e metodológicas, que foram tomadas ao longo destas três décadas de pesquisa.
From ethnography to evolution
Authors: Lull James
Published: January 2023

The author reflects on the development of his epistemic approach to the study of communication and culture first by recounting key experiences he had as a boy and young man, especially travel. He traces the trajectory of his empirical study of media, culture, and communication by citing key scholars and literature as well as his experiences as a professional communicator. Professor Lull’s doctoral dissertation at the University of Wisconsin-Madison, an innovative ethnography of family life with television, set him on the path of qualitative empirical research for much of his early career. He mentions his article “The Social Uses of Television” and his ethnography of the arrival of television in urban China as his major research accomplishments. In the late 1980s, his focus turned to Latin America, where he has given numerous presentations, seminars, and workshops. His collaboration with the Brazilian-American communications professor Eduardo Neiva helped bring about a transition to his most recent work, the introduction of evolutionary communication as a theoretical alternative in the field.
Oportunidades e vulnerabilidades do Brasil nas questões do clima e da sustentabilidade
Authors: Artaxo Paulo
Published: January 2023

As mudanças climáticas constituem um dos maiores desafios da humanidade hoje. É urgente entendermos como os ecossistemas brasileiros, a economia, a infraestrutura, as cadeias produtivas, a biodiversidade, a saúde, entre outros aspectos, estão sendo afetados pelas mudanças climáticas. O Brasil tem vantagens estratégicas enormes, como a possibilidade de reduzir fortemente as emissões de gases de efeito estufa, com ganhos importantes para a sociedade. Temos um potencial de geração de energia solar e eólica que nenhum outro país possui. Mas também temos vulnerabilidades, como um agronegócio dependente do clima e a geração de hidroeletricidade dependente da chuva. Temos também 8.500 km de áreas costeiras sensíveis ao aumento do nível do mar, e áreas urbanas vulneráveis a eventos climáticos extremos. Temos que construir uma socioeconomia mais justa e com clima e meio ambiente integrados de modo sustentável.
The Contributions of the Cerebellar Peduncles and the Frontal Aslant Tract in Mediating Speech Fluency
Authors: Jossinger Sivan , Yablonski Maya , Amir Ofer , Ben-Shachar Michal
Published: January 2023

Fluent speech production is a complex task that spans multiple processes, from conceptual framing and lexical access, through phonological encoding, to articulatory control. For the most part, imaging studies portraying the neural correlates of speech fluency tend to examine clinical populations sustaining speech impairments and focus on either lexical access or articulatory control, but not both. Here, we evaluated the contribution of the cerebellar peduncles to speech fluency by measuring the different components of the process in a sample of 45 neurotypical adults. Participants underwent an unstructured interview to assess their natural speaking rate and articulation rate, and completed timed semantic and phonemic fluency tasks to assess their verbal fluency. Diffusion magnetic resonance imaging with probabilistic tractography was used to segment the bilateral cerebellar peduncles (CPs) and frontal aslant tract (FAT), previously associated with speech production in clinical populations. Our results demonstrate distinct patterns of white matter associations with different fluency components. Specifically, verbal fluency is associated with the right superior CP, whereas speaking rate is associated with the right middle CP and bilateral FAT. No association is found with articulation rate in these pathways, in contrast to previous findings in persons who stutter. Our findings support the contribution of the cerebellum to aspects of speech production that go beyond articulatory control, such as lexical access, pragmatic or syntactic generation. Further, we demonstrate that distinct cerebellar pathways dissociate different components of speech fluency in neurotypical speakers.
Metrics for Evaluating Cyber Security Data Visualizations in Virtual Reality
Authors: Harris Daniel , Miknis Marius , Smith Connor , Wilson Ian
Published: January 2023

Cyber security analysts use data visualizations to speed up ingestion of security data. These visualizations typically take the form of 2D graphics displayed on computer monitors. Virtual reality has the potential to improve these visualizations with immersive 3D environments and unique interaction mechanics. However, research into this newly synergized area lacks evaluation, leading to unfounded claims of effectiveness. A potential cause for these missing evaluations was identified as a lack of guidance detailing how evaluations should be conducted in this area. Additionally, the small amount of research that does include evaluation incorrectly relies on subjective participant opinions to objectively measure system effectiveness. An example of this misuse is asking participants which system they thought was quicker, rather than timing them. The objective of this article is to propose a solution to these issues in the form of a surveyed, categorized, and analyzed set of evaluation metrics. A total of 49 metrics was identified from 41 papers. The presented metrics detail which dependent variables should be considered when evaluating works in the combined fields of cyber security, data visualization, and virtual reality. These metrics can be used to produce more accurate evaluations in future works in this area.
Libertarian Control and Ultimate Responsibility
Authors: Montminy Martin
Published: January 2023

I raise three new objections against Robert Kane’s account of ultimate responsibility based on what he calls self-forming actions (sfa s). First, the ultimate responsibility that we have for our character is very limited, since, according to Kane’s model of character development, our character is shaped by sfa s for which we are only minimally responsible. Second, it is not desirable to rely on sfa s to shape our character. There are much better alternatives. Third, given what typically motivates our sfa s, we only rarely satisfy the conditions on responsibility for the changes in character that our sfa s give rise to.
The Journal of Jesuit Studies: First Decade
Authors: van Dijk Arjan
Published: January 2023

On the occasion of its tenth anniversary, this article looks back on the genesis and subsequent development of the Journal of Jesuit Studies, its conversion to open access, and the role of its founding editor, Robert Aleksander Maryks. It also highlights a number of other Brill resources in Jesuit Studies conceived and edited by Robert Maryks.
Jesuits, Conspiracies, and Conspiracy Theories
Authors: McKenzie-McHarg Andrew
Published: January 2023

This introductory article explores the thematic affinity linking the Society of Jesus with conspiracies and conspiracy theories. After giving a short overview of the historiography devoted to anti-Jesuitism, it draws attention to how anti-Jesuits vilified the order over the centuries on the basis of alleged conspiracies whose extent varied from the episodic to the all-encompassing and that were imagined and posited in ways that tended to be themselves highly conspiratorial. In this manner, it foregrounds aspects of anti-Jesuitism and conspiracy theories that will recur in the individual contributions to this special issue of the Journal of Jesuit Studies.
How the Chinese in the Spanish Philippines Negotiated Commercial Boundaries in the Colonial Economy
Authors: Clemente Tina S.
Published: January 2023

While various dimensions of Chinese commercial achievement have gained longstanding attention in the literature, this article argues for the reconsideration of Chinese commercial performance in the Spanish Philippines based on the confluence of various factors, including the altered conditions of economic engagement in the islands, the character of political economy during the colonial period, and the gaps in provisioning the colony. Against the backdrop of the socio-political and economic dynamics of the Spanish empire, I analyze narratives that emanate from the interests of the colonial authorities, the clergy, and the Chinese traders themselves. I utilize sixteenth-to-eighteenth-century historical accounts and consider these narratives as frames of various motivations by the different actors. I examine these representations and underscore how the Chinese negotiated various parameters set against them that limited their access to commercial opportunities and settlement.
A new group of species of the genus Megalothorax (Collembola, Neelidae) with Gondwanan distribution, and introducing an open interactive identification key of Megalothorax species
Authors: SCHNEIDER CLÉMENT , MINOR MARIA A. , D’HAESE CYRILLE A.
Published: January 2023

Megalothorax Willem, 1900 is a genus of Neelidae (Collembola) with worldwide distribution. Three new species are described here: Megalothorax anterolenis sp. nov. (Patagonia, Chile), Megalothorax tasmanterolenis sp. nov. (Tasmania, Australia) and Megalothorax zealanterolenis sp. nov. (the South Island, New Zealand). New descriptive elements are also provided for Megalothorax rubidus. Two of the new species were sequenced (COI, 16S rDNA, 28S rDNA). Within the genus, the three new species form a new group of species characterised by the absence of secondary granulation dorsally on the head and the thorax, a reduced chaetotaxy of the basomedian field of labium, a bifurcate hair on the maxillary outer lobe and an enlarged S-chaeta (Sa2) on Ant. IV. The molecular based phylogeny further supports the sistership of the two sequenced species. The possible Gondwanan origin of the new group is discussed. Elements of discussion are also provided regarding the possible function of the incomplete coverage of secondary granulation. Finally, an open interactive identification key for the Megalothorax species of the world is introduced.
First molecular identification of Suillia gigantea (Meigen, 1830) (Diptera: Heleomyzidae)
Authors: ROSA-GRUSZECKA ALEKSANDRA , WOŹNICA ANDRZEJ JÓZEF , TEREBA ANNA , SZABŁOWSKI PRZEMYSŁAW , HILSZCZAŃSKA DOROTA
Published: January 2023

In 2017, the presence of the fly Suillia gigantea (Meigen, 1830) was noted in Poland, after many years of research related to the ecology of insects associated with the fruiting bodies of hypogeous fungi. Finally, in 2020, after further studies, the distribution of the truffle fly in Poland was confirmed. Six adults were reared from larvae inhabiting the fruiting bodies of Burgundy truffle (Tuber aestivum Vittad. (1831)). The fungi were harvested in southern Poland. Morphological and genetic analyses of the insect specimens were performed. For the first time, the DNA sequence of this fly species was isolated. This is the first record of S. gigantea in Poland, although it has already been reported from neighbouring countries. The development of S. gigantea, also known as the truffle fly, is associated with hypogeous fungi, mainly belonging to the genus Tuber P. Micheli ex F.H. Wigg. (1780). The diptera larvae develop inside the fruiting bodies. This type of damage causes great losses in truffle production. Containment of these losses is of great interest to the truffle industry. Knowledge of truffle-inhabiting insects is crucial for the development of effective methods to protect truffle crops in Europe.
A new distributional range of Abraxas antipusilla Inoue, 1995 (Lepidoptera: Geometridae) from Eastern Himalaya, India
Authors: GAYEN SUBRATA , CHANDRA KAILASH
Published: January 2023

Based on Indian Himalayan expeditions, the species Abraxas antipusilla Inoue, 1995 is reported for the first time from Eastern Himalaya, India. After two decades, differential diagnoses of males and females are presented in comparison to Abraxas pusilla Butler, 1880. Redescriptions of male and female genitalia are given. An annotated summary on habitat preference and distributional ranges for both species is emphasized within the Indian Himalayan Region.
Systematic study of Chinese Acroclita Lederer (Lepidoptera: Tortricidae), with the description of a new species
Authors: ZHANG AIHUAN
Published: January 2023

Five species of Acroclita Lederer, 1859 are reported from China, including Acroclita ovata sp. nov., which is described and illustrated from Hubei Province. The previously described species are listed along with references cited, host-plants, specimens examined, and distributions. A taxonomic key to Chinese species of Acroclita is presented based on characters of the male genitalia.
The revealing of a novel lipid transfer protein lineage in green algae
Authors: Huang Ming-Der , Wu Chin-Wei , Chou Hong-Yun , Cheng Sou-Yu , Chang Hsin-Yang
Published: January 2023

Background

Non-specific lipid transfer proteins (nsLTPs) are a group of small and basic proteins that can bind and transfer various lipid molecules to the apoplastic space. A typical nsLTP carries a conserved architecture termed eight-cysteine motif (8CM), a scaffold of loop-linked helices folding into a hydrophobic cavity for lipids binding. Encoded by a multigene family, nsLTPs are widely distributed in terrestrial plants from bryophytes to angiosperms with dozens of gene members in a single species. Although the nsLTPs in the most primitive plants such as Marchantia already reach 14 members and are divergent enough to form separate groups, so far none have been identified in any species of green algae.

Results

By using a refined searching strategy, we identified putative nsLTP genes in more than ten species of green algae as one or two genes per haploid genome but not in red and brown algae. The analyses show that the algal nsLTPs carry unique characteristics, including the extended 8CM spacing, larger molecular mass, lower pI value and multiple introns in a gene, which suggests that they could be a novel nsLTP lineage. Moreover, the results of further investigation on the two Chlamydomonas nsLTPs using transcript and protein assays demonstrated their late zygotic stage expression patterns and the canonical nsLTP properties were also verified, such as the fatty acids binding and proteinase resistance activities.

Conclusions

In conclusion, a novel nsLTP lineage is identified in green algae, which carries some unique sequences and molecular features that are distinguishable from those in land plants. Combined with the results of further examinations of the Chlamydomonas nsLTPs in vitro, possible roles of the algal nsLTPs are also suggested. This study not only reveals the existence of the nsLTPs in green algae but also contributes to facilitating future studies on this enigmatic protein family.
When epidemiological databases inform injury mechanisms: biomechanical analysis of injury associations
Authors: Bruna-Rosso Claire , Ballout Nadim , Arnoux Pierre-Jean , Ndiaye Amina , Martin Jean-Louis , Vernet Céline
Published: January 2023

Background

Vehicle accidents are still a heavy social burden despite improvements due the latest technologies and policies. To pursue the trend of decrease, having a more detailed view and understanding of the injury patterns would contribute to inform both the rescue team to optimize victim’s management and policymakers in order for them to tackle at best this issue.

Methods

Two complementary analyses of injury associations were performed, one using a biomechanical classification and the other an anatomic one, computed on data stratified by car accident type (lateral or frontal). Our objective is to understand whether these two categories of crash lead to similar or heterogeneous injury association patterns, and analyze these findings from an impact mechanics point of view. Indeed, having an improved understanding of the injury mechanisms would facilitate their diagnosis and prevention.

Results

While each type of accident possesses its own injury profile, most injury associations are found for both types. Injuries such as clavicle and rib fractures were identified as involved in a high number of associations. Several associations between fractures and blood vessel injuries were found.

Conclusions

The results suggests three main conclusions: (i) Injury associations are rather independent from crash characteristics, (ii) Clavicle and rib fractures are typical of poly-traumatized victims, (iii) Certain fractures can be used to early detect victims at higher risk of hemorrhage. Overall, this study provide paramedics and doctors with data to orientate them toward a faster and more appropriate decision. Moreover, this exploratory work revealed the potential that injury association analyses have to inform policy-making and issue recommendations to decrease road accident mortality and morbidity.
Nuestra Recuperación [Our Recovery]: using photovoice to understand the factors that influence recovery in Latinx populations
Authors: Muroff Jordana , Do Daniel , Brinkerhoff Cristina Araujo , Chassler Deborah , Cortes Myrna Alfaro , Baum Michelle , Guzman-Betancourt Genessis , Reyes Daniela , López Luz M. , Roberts Maylid , De Jesus Diliana , Stewart Emily , Martinez Linda Sprague
Published: January 2023

Background

Photovoice is a form of visual ethnography intended to engage impacted communities in research followed by action to ameliorate the injustices under study. Photovoice has increased in use, especially in collaboration with Latinx communities addressing health inequities. The Latinx population comprises nearly 18% of the overall United States population and according to the census is projected to reach just under 30% by 2060. This diverse panethnic community faces significant structural barriers in accessing services. Racism and the resulting marginalization, specifically, contributes to limited access to recovery services and treatment. Making meaningful advances in substance use disorder training, intervention and policy necessitates learning alongside the Latinx community.

Methods

We partnered with a Latinx serving integrated behavioral health and primary care setting in Boston Massachusetts to explore barriers and facilitators to recovery using photovoice. Spanish-speaking Latinx adults with a substance use disorder participated. The group met for three photovoice sessions over a six-week period. Together group members critically analyzed photographs using the SHOWeD method.

Results

Findings indicate a sense of purpose and meaning, security, faith and housing are important elements of recovery. The results illustrated the importance of sources of connection in maintaining sobriety. Through this photovoice project, Latinx Spanish speaking participants highlighted barriers and facilitators to their substance use disorder recovery which spanned individual, community, and structural levels.

Conclusions

The experiences and voices of the Latinx community are crucial to drive discussions that advance policy (e.g., housing stability and access), enhance providers’ understanding of Latinx Spanish-speakers' substance use disorder recovery, and inform culturally and linguistically appropriate services. This study demonstrated that photovoice is highly acceptable and feasible among Latinx clients receiving substance use disorder services. Visual images related to housing, faith, etc. communicate challenges, power structures, as well as hopes to policymakers at multiple levels (e.g., institution/ agency, state).