bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of the Risk Factors and a Prediction Model for Postherpetic Trigeminal Neuralgia Recurrence After Extracranial Nonsemilunar Ganglion Radiofrequency Thermocoagulation
Authors: Fei Yong
Published: October 2024

BACKGROUND: Extracranial nonsemilunar ganglion radiofrequency thermocoagulation in the treatment of postherpetic trigeminal neuralgia has significant clinical effects. However, the related risk factors for its recurrence have not been studied. OBJECTIVE: This study aimed to investigate the risk factors for the recurrence of postherpetic trigeminal neuralgia after extracranial nonsemilunar ganglion radiofrequency thermocoagulation, and to construct a recurrence prediction model. STUDY DESIGN: This is a single-center, retrospective observational study. SETTING: The study was conducted in the Department of Pain, Affiliated Hospital of Jiaxing College, Jiaxing, People’s Republic of China. METHODS: A total of 76 patients with postherpetic trigeminal neuralgia admitted to the First Hospital of Jiaxing from July 2013 through October 2021 were retrospectively analyzed. All patients were treated with computed tomography-guided extracranial nonsemilunar segment radiofrequency therapy. The Kaplan-Meier method was used for survival analysis, the log-rank test was used, and the Cox proportional hazards regression model was used to analyze the clinical factors affecting postherpetic trigeminal neuralgia recurrence after extracranial nosemilunar ganglia radiofrequency thermocoagulation; in addition, a recurrence prediction model was established. RESULTS: Patients were followed-up for 12 months. A univariate analysis showed that age and disease duration are the factors affecting postherpetic trigeminal neuralgia recurrence after extracranial nonsemilunar ganglion radiofrequency thermocoagulation (P < 0.05). A multivariate Cox proportional hazards regression analysis showed that age and disease duration were independent influencing factors. The recurrence risk function model is expressed as follows. H (t) = h0exp (1.116 X1 + 1.340 X2), where X1 and X2 represent age and disease duration, respectively. The likelihood ratio of the model was tested, and the likelihood ratio was 195.776, showing statistical significance. LIMITATIONS: We look forward to increasing the sample size in subsequent studies and exploring relevant conclusions in randomized controlled trials. CONCLUSION: A short disease duration and young age can reduce the risk of recurrence after extracranial nonsemilunar ganglia radiofrequency thermocoagulation in patients with postherpetic trigeminal neuralgia. Our established recurrence prediction model can provide a reference for clinical diagnosis and treatment. KEY WORDS: Postherpetic trigeminal neuralgia,; radiofrequency ablation, recurrence, risk factors, prediction model
Safety and Efficacy of Intravenous ExoFlo in the Treatment of Complex Regional Pain Syndrome
Authors: Paicius Rick
Published: October 2024

BACKGROUND: Complex regional pain syndrome (CRPS) is an extremely painful disorder driven primarily by inflammation. OBJECTIVES: We hypothesized that the immunomodulatory biologic, ExoFloTM, composed of bone marrow mesenchymal stem cell-derived extracellular vesicles, could be safely administered to CRPS patients and alleviate symptoms. STUDY DESIGN: Ten patients received 2 intravenous (IV) infusions, each containing 15 mL ExoFlo, on day one and day 4. A series of tests were performed at baseline (day 0, prior to infusion), week one, and months one, 3, and 6 after the second infusion. SETTING: All patients were treated in one of 2 outpatient pain management clinics in Orange County, CA. METHODS: Testing for clinical improvement included: visual analog scale of pain, brief pain inventory, 36-item short-form questionnaire, range of motion analysis, and jamar dynamometer testing. RESULTS: No serious adverse events related to ExoFlo treatment occurred. Statistically significant improvements in pain and motion assessments occurred across the patient pool. LIMITATIONS: This study was limited by its patient number enrolled (10), it lacked a control arm, and one patient who dropped out of the study. CONCLUSIONS: IV delivery of ExoFlo appears safe in patients with CRPS. In addition, ExoFlo exhibited efficacy in addressing CRPS symptoms. Given the lack of effective and safe treatments available to CRPS patients, these results suggest that further studies are warranted to explore and validate this potential treatment for CRPS. KEY WORDS: Complex regional pain syndrome (CRPS), mesenchymal stem cell, extracellular vesicle, ExoFlo
Comparison of Spinoglenoid Versus Suprascapular Notch Approaches for Ultrasound-Guided Distal Suprascapular Nerve Blocks for Shoulder Pain: A Prospective Randomized Trial
Authors: Yildizhan Ridvan
Published: October 2024

BACKGROUND: Distal suprascapular nerve blocks (SSNB) can be performed at the level of the suprascapular notch (the preferred site) or at the level of the spinoglenoid notch. OBJECTIVES: To compare the efficacy and safety of spinoglenoid versus suprascapular notch approaches for ultrasound (US)-guided distal SSNB in patients with chronic shoulder pain. STUDY DESIGN: Prospective randomized controlled trial. SETTING: Outpatient physical medicine and rehabilitation outpatient clinic of a tertiary center. METHODS: Eighty patients with chronic unilateral shoulder pain were included in this study. Patients were randomized into 2 groups: group 1 (SSNB at the level of the spinoglenoid notch) and group 2 (SSNB at the level of the suprascapular notch). The patients were evaluated for pain according to the Shoulder Pain and Disability Index (SPADI) and a secondary visual analog scale (VAS), as well as for the outcome measures of range of motion (ROM) and pain pressure threshold (PPT) at baseline and at one, 4, and 12 weeks after the injection. RESULTS: Statistically significant improvement was observed in the SPADI and VAS scores and ROM measurements, and the PPT measurements were similar at all post-injection follow-ups in both groups. Changes in outcome measures were similar between the groups, except for some ROM measurements at the post-injection follow-ups. LIMITATIONS: Heterogeneity of shoulder pain etiologies. CONCLUSION: Both distal SSNB approaches significantly improved pain and disability scores in patients with chronic shoulder pain, with no observable differences in the short-to-medium term. SSNB performed at the level of the spinoglenoid notch is therefore not inferior in efficacy and safety to SSNB performed at the level of the suprascapular notch. KEY WORDS: Shoulder pain, suprascapular nerve block, spinoglenoid notch, suprascapular notch, ultrasound
A Randomized Controlled Trial Comparing the Effect of Two-Time Durations of Balloon Compression During Percutaneous Balloon Compression in Resistant Trigeminal Neuralgia
Authors: Verma Nimisha
Published: October 2024

BACKGROUND: Percutaneous balloon compression of the trigeminal nerve’s gasserian ganglion for the treatment of trigeminal neuralgia is an interventional pain procedure with results comparable to microvascular decompression surgery. The procedure is safe in experienced hands and has less morbidity associated with it. However, there is a lack of clear-cut guidelines about the details of the technique like balloon shape, inflation pressure, and duration of inflation. So, keeping the inflation pressure and shape of the balloon constant, we studied the effect of the duration of inflation of the balloon and its effect on pain relief in refractory trigeminal neuralgia cases. OBJECTIVES: To study the outcome with 2 different durations of balloon inflation times in terms of pain relief and complications after percutaneous balloon compression. STUDY DESIGN: Prospective parallel design randomized, controlled trial. SETTING: The study was conducted in a tertiary care hospital in North Eastern India after obtaining approval from the Institutes’ ethics committee (Dean/2018/EC/449). The study was also registered with the Clinical Trials Registry of India (CTRI no. CTRI/2019/03/018166). All patients referred to a pain clinic for unilateral facial pain were screened for the study over 2 years from April 2019 to March 2021. METHODS: Forty patients who met the diagnosis of trigeminal neuralgia and who did not respond satisfactorily to medications were included in the study. They underwent routine blood investigations and a magnetic resonance image of the brain to rule out any medical or surgical conditions. Percutaneous balloon compression was conducted under C-arm guidance using a 12 gauge cannula and a 4 Fr Fogarty balloon was used for compressing the gasserian rootlets. RESULTS: Patients who underwent 90 seconds as well as 120 seconds showed good pain relief. The 2 groups did not show any significant difference in pain relief based on the duration of compression. Visual analog scale scores were reduced from 7-8 to 0-3. Masseter muscle weakness was present in 47.5% of patients post-procedure and recovered in all except one patient. LIMITATIONS: We have followed up with our patients for a short period of 6 months only. We could not measure the intra-luminal compression pressure of the balloon. CONCLUSION: There is no difference in the pain relief obtained by the 2 different durations of compressions. A longer duration of compression, however, has more incidence of side effects. KEY WORDS: Idiopathic trigeminal neuralgia, percutaneous balloon compression, time duration, shape of balloon, masseter muscle weakness, facial numbness, corneal dysesthesia
Pain Characteristics of Patients With Fibromyalgia: A Comparison Between Gender and Different Emotional States
Authors: Jiang Ronghuan
Published: October 2024

BACKGROUND: Generalized pain is the core symptom of fibromyalgia (FM). Few studies have described FM’s different pain characteristics under various conditions. OBJECTIVE: To explore the pain characteristics of patients with FM of different gender and emotional states. STUDY DESIGN: A cross-sectional study. SETTING: A medical center in Beijing, People’s Republic of China. METHODS: A total of 197 patients with FM were recruited from an outpatient clinic. Three distinct instruments were used to assess their pain characteristics: the Numeric Rating Scale (NRS-11) to assess pain severity, the Widespread Pain Index (WPI) to assess the number of pain regions, and the Short Form-McGill Pain Questionnaire-2 (SF-MPQ-2) to assess pain qualities. The Zung Self-Rating Anxiety Scale and Zung Self-Rating Depression Scale were used to assess patients’ emotional states. An independent 2-sample t test, chi-squared test, and Mann-Whitney U test were used to analyze gender pain characteristics differences and different emotional states (with/without anxiety, with/without depression). RESULTS: Pain severity on the NRS-11 was 7 (5–8), the number of pain regions determined by WPI was 13 (10–16), and the total score of different pain qualities from the SF-MPQ-2 was 2.36 (1.68–3.73) in all patients with FM. The most frequently reported regions of pain were the right shoulder girdle (89.34%), left shoulder girdle (88.32%), upper back (85.28%), and neck (81.73%). The most frequently reported pain qualities were tiredness/exhaustion (97.46%), aching pain (94.42%), numbness (78.68%), cold/freezing pain (75.63%), and tenderness (75.13%). Women patients reported more severe pain and numbness, less frequent chest pain, and shooting pain than men patients did. Patients with FM and anxiety experienced more frequent and more severe feelings of punishing/cruel thoughts, fearfulness, sickening, and tenderness; more frequent jaw pain and cold-freezing pain; more severe pain caused by light touch and tiredness/exhaustion; less frequent lower leg pain than those without anxiety did. Patients with FM and depression reported more frequent and more severe pain caused by light touch; more frequent tenderness; more severe feelings of tiredness/exhaustion, sickening,fearfulness, and punishing/cruel thoughts; and less frequent and less severe piercing pain than those without depression did. LIMITATIONS: The limitations of this study are its single-center design and lack of objective pain indicators. CONCLUSION: Gender significantly affected pain severity, chest pain, numbness, and shooting pain. Jaw pain, lower leg pain, cold/freezing pain, tenderness, pain caused by light touch, piercing pain, and pain-affective descriptors are closely related to emotional states in FM. A comprehensive understanding of pain characteristics in patients with FM would be helpful for disease education, diagnosis, and treatment. KEY WORDS: Fibromyalgia, men, women, anxiety, depression, pain severity, pain regions, pain quality
Posterior Percutaneous Endoscopic Cervical Discectomy for Single-Level Soft, Huge Central Disc Herniation
Authors: Li Shun
Published: October 2024

BACKGROUND: Posterior percutaneous endoscopic cervical discectomy (PPECD) has been proven safe and effective for foraminal cervical disc herniation (CDH). However, central CDH has long been considered as the contraindication of PPECD, because the path is obstructed by the spinal cord and nerve root. OBJECTIVES: To preliminarily assess the feasibility, safety, and effectiveness of PPECD for single-level soft, huge central CDH. STUDY DESIGN: A retrospective cohort study. SETTING: Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital, Hangzhou Medical College). METHODS: Between 2017 and 2020, 31 patients diagnosed with single-level soft, huge central CDH were treated by PPECD. Primary outcomes included the measures of neck and radicular pain based on the numeric rating scale (NRS) and cervical neurologic status based on the Japanese Orthopedic Association (JOA) score. The global outcome was assessed using the Odom’s criteria at one-year follow-up. RESULTS: Compared to the baseline, there was a constant and significant reduction of NRS-rated pain and improvement of JOA-rated cervical neurologic status postoperatively (P < 0.01). According to the Odom’s criteria, 96.8% (30/31) of patients had satisfactory postoperative clinical improvement (excellent or good outcomes) at one-year follow-up. Complications included C5 nerve root palsy and spinal cord injury. The total complication rate was 16.5% (2/31), but these complications were temporary and not catastrophic. LIMITATIONS: The limitations of this study include the volume of the sample, a short follow-up period, and the lack of a control group. CONCLUSIONS: Our preliminary experience indicates that PPECD is a feasible and promising alternative for symptomatic single-level soft, huge central CDH. KEY WORDS: Intervertebral disc displacement, minimally invasive surgical procedures, diskectomy, endoscopy
IMPLEMENTASI SEKOLAH TANGGUH BENCANA GEMPA BUMI PADA MI MUHAMMADIYAH PK KATEGUHAN, KECAMATAN SAWIT, KABUPATEN BOYOLALI, JAWA TENGAH
Authors: Fathi Yakan Annisa , Maharani Alya , Putri Maharani Mentari , Wira Adyatma Hafiz
Published: October 2024

Kabupaten Boyolali memiliki potensi terdampak bencana gempa bumi. Kabupaten Boyolali memiliki risiko sedang akan bencana gempa bumi. Tingkat kerentanan bencana gempa bumi pada Kabupaten Boyolali berada pada kategori tinggi dengan kategori kapasitas yang sedang. Suatu daerah perlu meningkatkan kapasitas agar risiko bencana dapat diminimalisir. Salah satu cara dalam meningkatkan kapasitas adalah dengan mengadakan kegiatan sosialisasi sekolah siaga bencana. Sekolah siaga bencana dilakukan dengan tujuan meminimalkan kerentanan yang berasal dari kelompok rentan, yaitu anak – anak sekolah tingkat dasar. Kegiatan pengabdian ini penting dilakukan menimbang MIM PK Kateguhan belum memiliki kegiatan sosialisasi kebencanaan di sekolah.  Kegiatan pengabdian ini terdiri dari pelaksanaan pre-test, sosialisasi mengenai bencana gempa bumi, dan pelaksanaan post-test. Responden pengabdian ini adalah siswa siswi kelas 5 SD yang berjumlah kurang lebih 50 orang. Keberhasilan kegiatan ini dilakukan dengan mengevaluasi pre-test dan post-test yang diberikan. Terjadi kenaikan nilai post test sebesar 17.3% setelah diberikan materi bencana bumi. Hal tersebut menggambarkan bahwa kegiatan pengabdian ini bisa dikategorikan berhasil.
Originalidad doctrinal Humanae vitae
Authors: Mattheeuws Alain
Published: October 2024

El presente artículo pone en evidencia una de las dificultades que se encuentran en la recepción de la Humanae vitae y de la Familiaris consortio: la profundidad del sentido de todo acto conyugal, su belleza y su vínculo explicito con el Creador. Esta paradoja provoca en primer lugar la fe de los bautizados en el misterio de Dios, que es amor y vida, y en segundo término la conciencia moral. ¿No sería acaso demasiado hermoso para ser verdad? Sin embargo, la unión de los cónyuges es primero un acto religioso. El principal enunciado doctrinal envuelve la unión de los esposos y su responsabilidad parental. La verdadera “cuna” antropológica de todo ser humano es un acto de amor interpersonal. Este acto particular, rico y complejo, tiene un doble significado: unitivo y procreativo. Estos significados se amalgaman entre ellos, y traducen la unidad de las personas que se donan una a la otra. Es el gran misterio que une a los esposos y a Dios; y es el lugar de una revelación.
Prolegomeni allo studio dei parlanti ereditari di sardo
Authors: Lai Rosangela
Published: October 2024

When a minority language holds a subordinate position and is neglected or abandoned in family communication, some speakers acquire it imperfectly, resulting in limited proficiency; these individuals are known as heritage speakers. However, some heritage speakers later develop an attachment to their ancestral language and choose to study it in formal or informal educational settings, becoming heritage learners. This study focuses on heritage learners of Sardinian, a Romance language spoken in Sardinia. Today, most Sardinian residents under fifty primarily speak Italian, but there is a growing interest in Sardinian language courses aimed at reconnecting community members with their linguistic heritage. This research examines the grammatical and lexical competence of a sample of these heritage learners, particularly focusing on areas identified in the literature as vulnerable to erosion and interference from Italian. Specifically, it will demonstrate that in instances of grammatical or lexical divergence between Sardinian and Italian, heritage learners tend to accept both idiomatic Sardinian forms and Italian-influenced forms, indicating significant interference in their proficiency of the minority language. This study aims to help language teachers develop targeted interventions to enhance the competence of heritage learners, differentiating from curricula designed for second language learners of Sardinian when necessary.
Misión de la universidad
Authors: Ortega Ruiz Pedro
Published: October 2024

El autor describe la situación por la que atraviesa la universidad española, extrapolable, en gran medida, a la universidad latinoamericana. El autor circunscribe su trabajo a responder a las siguientes preguntas: a) ¿qué está pasando en la sociedad occidental?; b) ¿qué universidad tenemos?; c) ¿qué universidad necesitamos?; y d) ¿qué hacer? El autor aboga por “otra enseñanza” que introduzca la ética en el corazón del aprendizaje de la universidad, que además de preparar buenos profesionales favorezca la formación de ciudadanos responsables al servicio del bien común. Y parte de dos líneas de actuación: a) un nuevo concepto del hombre como ser histórico, circunstancial. El ser humano que conocemos por la experiencia no es una idea universal, abstracta; es el ser que hace del contexto o circunstancia su hábitat natural, y b) el hombre como ser relacional, abierto al otro y responsable de él. Es el otro quien nos hace humanos. La responsabilidad se convierte, así, en el núcleo de toda educación o formación ciudadana.
La educación conciente en la agenda progresista. El caso colombiano
Authors: Arboleda Julio César
Published: October 2024

El propósito de esta exposición de resorte reflexivo-generativo, es proyectar ciertas luces para que las agendas, proyectos y programas políticos en desarrollo o previamente a su implementación, en especial aquellas de resorte progresista y afines, en sus líneas educativas, en particular, sean, tanto como las reacciones que a favor y/o en contra despiertan, (re)pensadas de cara a asumir con conciencia edificante sus acciones y su (re)construcción permanente. Se trata de sentipensar las agendas políticas y las críticas que buscan nutrirlas o aminorarlas, de modo que en lo posible ganen luminosidad, y promuevan una educación más conciente; en todo caso, para que la educación y la política se resignifiquen. Una de las grandes deudas de la política, y por supuesto de la educación, es que cada vez se alejan de la misión primada que les impone generar escenarios para fluir con la vida entrelazada, seamos dignos habitantes de la casa común, proximales, acogientes del otro humano y de lo otro no humano.
La educación global cómo impulsar la ciudadanía global desde la escuela
Authors: Atahuachi Mucho Hugo , García Pando Flor de María
Published: October 2024

El artículo informa de una investigación que analiza diversas publicaciones de autores, en relación a la educación global para mejorar el mundo. El objetivo es contribuir a la conciencia reflexiva o autoconcienca del surgimiento y/o formación de nuevos ciudadanos con mentalidad de una ciudadanía mundial a través del impulso y tratamiento pedagógico desde las escuelas. Se presenta un panorama general del pensamiento sobre la educación planetaria desde diferentes enfoques, utilizando la metodología cualitativa y empleando la técnica de análisis de contenido. Durante la investigación, también se hizo la selección de informaciones más relevantes, se redactó el informe que esclarece conceptualmente constructos como educación global, la educación global como proceso transformador de aprendizaje, ¿por qué una educación global?, aprendizaje para una sociedad global, centros educativos y el enfoque de ciudadanía mundial; posteriormente se elaboró una tabla con los estudios realizado sobre el tema, objetivos y resultados y por último se realizó las conclusiones
Plasma Rico em Plaquetas (PRP) na Dermatologia: Eficácia, Aplicações e Desafios na Regeneração Cutânea
Authors: Paulino Fogaça dos Santos Gabriela , Dossena Carolina , Nantes Fontoura Teofilo Rhuan , Marone Barros Lopes Sávio , Borghi Tamura Medeiros Bárbara , Guan Yinlan , Nogueira de Freitas Lívia , Ferreira Baduy Giovana , Pedro de Oliveira Lorena , Rodrigues de Freitas Lucas Mateus , Veiga Cazella Franciane , Bauml Braznik Mariane , Malachias de Andrade Bergamo Fernando , Mota Milhomem Beatriz , Martins Bitanti Rafael
Published: October 2024

INTRODUÇÃO: O plasma rico em plaquetas (PRP) tem se destacado como uma terapia inovadora em diversas áreas da medicina, especialmente na dermatologia e estética. O PRP, um concentrado autólogo de plaquetas obtido por meio da centrifugação do sangue, é conhecido por suas propriedades regenerativas e reparadoras, sendo utilizado em tratamentos como rejuvenescimento facial, cicatrização de úlceras crônicas e fortalecimento capilar. OBJETIVO: O objetivo principal desta revisão é analisar a eficácia do PRP em diferentes contextos clínicos e estéticos, avaliando sua aplicação no tratamento de condições como alopecia, envelhecimento cutâneo e cicatrização de feridas. METODOLOGIA: A revisão foi conduzida seguindo as diretrizes do PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses), com a seleção de artigos relevantes nas bases de dados PubMed e BVS. Foram incluídos estudos que abordavam o uso do PRP em tratamentos estéticos e clínicos, com foco em sua eficácia e segurança. A busca foi realizada entre 2012 a 2023, resultando na inclusão de 14 artigos que atendiam aos critérios de elegibilidade. RESULTADOS: Os resultados indicam que o PRP é eficaz no tratamento da alopecia androgenética, promovendo a revitalização dos folículos capilares e aumentando a densidade capilar. Além disso, a aplicação de PRP no rejuvenescimento facial demonstrou melhorias significativas na textura e elasticidade da pele, com a estimulação da produção de colágeno e elastina. CONCLUSÃO: O PRP se apresenta como uma terapia promissora e multifacetada, com aplicações significativas na medicina estética e regenerativa. A evidência acumulada sugere que o PRP é uma opção eficaz e segura para o tratamento de condições capilares, rejuvenescimento facial e cicatrização de feridas. No entanto, a necessidade de mais estudos para padronizar os métodos de obtenção e aplicação do PRP é evidente, assim como a importância de personalizar os protocolos de tratamento de acordo com as características individuais dos pacientes. A continuidade da pesquisa nesta área é essencial para explorar plenamente o potencial terapêutico do PRP e estabelecer diretrizes clínicas robustas.
Abordagens Integradas no Tratamento da Esclerose Lateral Amiotrófica: Perspectivas e Resultados
Authors: Lucena Santos Priscylla , Almeida Pessoa Rodrigues de Araújo Bianca , Willy Duarte Magalhães Aliandro , Tavares Carreiro Roberto , Dos Santos Moitinho Denise , Gustavo Rodrigues Colpani Franciely , Figueira da Costa Déborah , Pedro de Assis Ferrari João , Aparecido Irrazabal Leandro , Fernando Lima Ribeiro Caio , Garcia Aguiar Breno , Riquieli Artmann Tainá , Matheus Ribeiro Baylão Victor , Motteran Cândido Alysson , Busnardo Paschoalino Brunno
Published: October 2024

Introdução: A Esclerose Lateral Amiotrófica (ELA) é uma doença neurodegenerativa progressiva que afeta as células motoras do cérebro e da medula espinhal, levando à perda gradual da função muscular e à incapacitação dos pacientes. Dada a complexidade e a natureza multifacetada da ELA, seu tratamento demanda uma abordagem integrada, buscando não apenas o manejo dos sintomas físicos, mas também o apoio emocional e social, reconhecendo a importância de um tratamento centrado no paciente. Objetivo: Avaliar a eficácia de diferentes métodos de tratamento para a ELA, destacando a importância da abordagem multidisciplinar na melhoria da qualidade de vida dos pacientes. Metodologia:  Foram utilizadas as bases de dados Cochrane, Scielo e Medline, buscando artigos publicados entre os anos de 2022 e 2024, nos idiomas Português ou Inglês. Considerações Finais: As abordagens integradas no tratamento da Esclerose Lateral Amiotrófica demonstram ser essenciais para melhorar a qualidade de vida dos pacientes, ao unir esforços de profissionais de diversas áreas da saúde. Essa estratégia multidisciplinar permite um manejo mais eficaz dos sintomas e oferece suporte emocional e social, adaptando-se às necessidades individuais à medida que a doença avança.
INFLUENCE OF SUPERVENOUS LASER IRRADIATION OF BLOOD ON CYTOKINE STATUS OF BLOOD IN PATIENTS WITH TRUE ECZEMA
Authors: Донцова Е.В. , Борзунова Л.Н. , Бахметьев А.А. , Быкова Ю.Н.
Published: October 2024

Ввиду недостаточной эффективности известных на сегодняшний день методов лечения пациентов с истинной экземой (ИЭ) существует необходимость поиска новых подходов для решения данной проблемы. Целью исследования было изучение влияния надвенного лазерного облучения крови на цитокиновый статус крови при лечении пациентов с истинной экземой. В группе из 66 больных с истинной экземой проводилась сравнительная оценка цитокинового потенциала крови при стандартной медикаментозной терапии (Ст, 33 пациента) и комплексном лечении, дополненного применением надвенного лазерного облучения крови (НЛОК+Ст, 33 пациента). Установлено, что уровень цитокинов ИЛ -4, -8, -18, -31 крови в группе Ст после лечения статистически значимо не изменился (р>0,05). При совместном применении НЛОК и Ст произошло значительное снижение концентрации провоспалительных цитокинов ИЛ-8,-18,-31 и повышение активности противовоспалительного цитокина ИЛ-4 по сравнению со стандартной терапией. Комбинированный метод лечения обеспечил более эффективное уменьшение выраженности проявления ИЭ по индексу EASI: в группе НЛОК+Ст EASI через 1 месяц от начала лечения индекс EASI снизился в 2,4 раза, при стандартном лечении - в 1,28 раза

Due to the insufficient effectiveness of currently known methods for treating patients with true eczema (IE), there is a need to find new approaches to solving this problem. The aim of the study was to investigate the effect of supravenous laser irradiation of blood on the cytokine status of blood in the treatment of patients with true eczema. In a group of 66 patients with true eczema, a comparative assessment of the cytokine potential of the blood was performed during standard drug therapy (St, 33 patients) and complex treatment supplemented with the use of intravenous laser irradiation of the blood (NLBI + St, 33 patients). It was found that the level of cytokines IL-4, -8, -18, -31 in the blood in the St group after treatment did not change statistically significantly (p> 0.05). With the combined use of NLBI and St, there was a significant decrease in the concentration of proinflammatory cytokines IL-8, -18, -31 and an increase in the activity of the anti-inflammatory cytokine IL-4 compared to standard therapy. The combined treatment method ensured a more effective decrease in the severity of IE according to the EASI index: in the NLBI + St EASI group, after 1 month from the start of treatment, the EASI index decreased by 2.4 times, with standard treatment - by 1.28 times
DEVELOPMENT OF THE PROJECT OF THE MEDICAL INFORMATION SUBSYSTEM "HOSPITAL PHARMACY"
Authors: Лебедев И.А. , Сергеева М.А.
Published: October 2024

Больничная аптека – это аптека, которая находится на территории медицинского учреждения, такого как больница или поликлиника. Она предназначена для обеспечения пациентов лекарственными препаратами, медицинскими изделиями и другими товарами, необходимыми для лечения и ухода за больными. Современные медицинские организации производят и накапливают огромные объемы данных. От того, насколько эффективно эта информация используется врачами, руководителями, управляющими органами, зависит качество медицинской помощи, общий уровень жизни населения, уровень развития страны в целом и каждого ее территориального субъекта в частности. Поэтому необходимость использования больших, и при этом еще постоянно растущих, объемов информации при решении диагностических, терапевтических и других задач, обуславливает сегодня создание информационных систем в медицинских учреждениях. В статье рассматривается разработка подсистемы «Больничная аптека» программного комплекса МИС, предназначенной для автоматизации деятельности аптечного склада медицинской организации (МО)

A hospital pharmacy is a pharmacy that is located on the territory of a medical institution, such as a hospital or polyclinic. It is designed to provide patients with medicines, medical devices and other goods necessary for the treatment and care of patients. Modern medical organizations produce and accumulate huge amounts of data. The quality of medical care, the general standard of living of the population, the level of development of the country as a whole and each of its territorial subjects in particular depend on how effectively this information is used by doctors, managers, and governing bodies. Therefore, the need to use large, and at the same time still constantly growing, volumes of information in solving diagnostic, therapeutic and other tasks, determines the creation of information systems in medical institutions today. The article discusses the development of the subsystem "Hospital pharmacy" of the MIS software package designed to automate the activities of the pharmacy warehouse of a medical organization (MO)
Structural Integrity, Environmental Sustainability, and Cost-Effectiveness of Fly Ash Bricks
Authors: Parth Vishnubhai Prajapati
Published: October 2024

The construction industry and environmental advocates have increasingly focused on sustainable, long-lasting, and cost-effective building materials in modern construction. Clay bricks and concrete, traditional construction materials, are used extensively, but their environmental impact and resource-intensive production processes are raising concerns. Fly ash bricks, created from industrial waste, have emerged as a promising alternative, offering a unique combination of structural integrity, environmental sustainability, and cost-effectiveness, making them an appealing option for the construction industry. Fly ash, a by-product of coal combustion mainly from power plants was previously considered a pollutant and a disposal challenge. However, the innovative use of fly ash in brick production has transformed this waste into a valuable resource. As awareness of sustainability and eco-friendly building practices has grown, fly ash bricks have gained widespread recognition as a greener alternative to traditional materials like clay bricks and concrete blocks
Metode Langsung dalam Pembelajaran Sekar raré pada Pertunjukan Jangér Sakral Banjar Kedaton Desa Adat Sumerta
Authors: Bagus Angga I Made Bagus Angga Putra
Published: October 2024

The existence of Jangér in Banjar Kedaton remains well-preserved to this day. The Jangér songs in Banjar Kedaton, Desa Adat Sumerta, possess distinctive characteristics, values, and unique qualities in both their melodies and performances. Despite various training methods being employed for Jangér songs, their effectiveness has been found lacking. Consequently, trainers have concluded that the Direct Method is the most effective teaching approach. This study addresses three research questions: (1) the application of the Direct Method in teaching sekar raré for Jangér performances, (2) the challenges encountered when implementing this method, and (3) strategies to overcome these challenges. The aim of this research is to provide insights to dancers, trainers, researchers, and government institutions about the Direct Method. Using a qualitative approach and the theories of Behaviorism and Constructivism, this study finds that the application of the Direct Method faces obstacles such as the availability of trainers, dancers' skills, and training time. Mention the Proposed solutions, among others include encouraging dancers to practice Jangér songs more at home.
Different Culture Means Different Discourse Perception: Personal True-based Story in Light of Face-Threatening Acts
Authors: Almoayidi Khedir
Published: October 2024

One of the driving motives of language use is to pave the way for communication and understanding. However, sometimes the exclusive use of language cannot help to stream mutual understanding among people who have different cultures which, unfortunately, researchers have not treated in much detail. As such, this study brings to light the essential role of cultural norms and conventions in interaction. Based on a true story, the current study shows that different cultural norms can raise issues that cause misunderstanding and could lead to face threatening acts. This manifests that being aware of the interaction conventions of one’s culture does not necessarily mean that speakers of other cultures will have the same conventions, and what speakers of a certain culture consider to be polite may be considered impolite and trespassing in other cultures.
Aspek Etis Penerapan Desain Penelitian Eksperimen dalam Pendidikan Sains
Authors: Frantius Deklin
Published: October 2024

Science education aims to convey science to students so that science can be transmitted according to its nature. Various scientific studies have been conducted to develop better teaching strategies. The research was conducted with the principle of the scientific method, experimental research design. In principle, it aims to test a treatment of research objects. In educational research, the tested treatment or learning model will be applied to the experimental group while the control group will not receive the additional treatment. Methodologically, the design is certainly in accordance with the purpose of the hypothesis. However, this will certainly be contradictive to ethical issues if the involved research objects are humans. The principle of fairness needs to be considered between the experimental group and the control group. It is guaranteed that all participants receive the same benefits. Therefore, it is necessary to study the ethical aspects of experimental research design in science education.
SEHAT MENTAL FOR CAREGIVER MELALUI PELATIHAN PENERAPAN METODE STOISISME UNTUK MENURUNKAN STRES : DALAM MERAWAT LANSIA DEMENSIA
Authors: Chusnul Chotimah  , Siti Aminah  , Melisa
Published: October 2024

Pendahuluan : Keluarga berperan sebagai support system utamabagi lansia dalam mempertahankan kesehatannya. Perawatandemensia, sekitar 70% dilakukan dirumah, hal ini dapatmenimbulkan permasalahan pada keluarga. Mengatasipermasalah yang muncul ditawarkan salah satu pelatihan berisitentang edukasi demensia dan cara perawatannya serta penerapanStoisisme yang bertujuan mencapai kebahagiaan, ketenangan,kebebasan dari emosi yang merusak dan penguasaan ataskeinginan.
Metode : Metode PAR (Participatory Action Research)digunakan dalam pengabdian masyarakat ini.
Hasil : Pelatihan dan penerapan metode Stoisisme denganmenggunakan teknik STAR (Stop-Think and Assess-Respon)memberikan pengaruh terhadap perubahan sikap dan perilakucaregiver terhadap penilaian stres dalam merawat lansia dengandemensia. Hasil evaluasi selama satu minggu setelah pelatihan,keluarga menyampaikan emosi lebih stabil tidak mudah marah-marah, lebih sabar, menilai segala sesuatu sebagai suatu ibadah.
Kesimpulan : Pelatihan dan penerapan metode Stoisismedengan menggunakan teknik STAR (Stop-Think and Assess-Respon) memberikan pengaruh terhadap perubahan sikap danperilaku caregiver terhadap penilaian stres dalam merawat lansiadengan demensia.
Prevalencia de hipoacusia neurosensorial en músicos que trabajan en bares de Bogotá, Colombia
Authors: Valbuena Sandra Patricia , Jiménez Guerrero Leidy Nathaly , Peña Naranjo Juan Carlos , Castro Carlos Alberto , Méndez Jacobo Enrique
Published: October 2024

Introducción: los músicos tienen riesgo de pérdida auditiva al estar expuestos a la música amplificada y no utilizar protectores auditivos. El objetivo es determinar la prevalencia de hipoacusia neurosensorial en músicos que laboran en bares de una localidad de la ciudad de Bogotá, Colombia. Métodos: estudio de corte transversal descriptivo; se seleccionaron 80 músicos, se realizó examen físico, audiometría tonal, audiometría de altas frecuencias, logoaudiometría e impedanciometría. Resultados: 43 sujetos presentaron hipoacusia (53,7%), 16 hipoacusia unilateral (20%) y 27 hipoacusia bilateral con una prevalencia de 33,7%. La mediana de edad fue de 29 años, los síntomas más referidos fueron tinnitus, hiperacusias e hipoacusia. La mayor prevalencia de hipoacusia fue en músicos que interpretan rock y música clásica e instrumentos de cuerda. Conclusiones: la prevalencia de hipoacusia en esta muestra es similar a estudios previos; el no uso de protectores auditivos puede estar relacionado con la pérdida auditiva.
Justification of the structural and functional scheme and creation of a combined implement for vertical tillage
Authors:   MECHANICS and AUTOMATICS of AGROINDUSTRIAL PRODUCTION of the NATIONAL ACADEMY of AGRARIAN SCIENCES of UKRAINE, Adamchuk V. , Korniushyn V. ,   MECHANICS and AUTOMATICS of AGROINDUSTRIAL PRODUCTION of the NATIONAL ACADEMY of AGRARIAN SCIENCES of UKRAINE, Ponomar Y. ,   Krasnyanske JV Agromash LLC, Nasonov V. ,   MECHANICS and AUTOMATICS of AGROINDUSTRIAL PRODUCTION of the NATIONAL ACADEMY of AGRARIAN SCIENCES of UKRAINE, Sidy M. ,   MECHANICS and AUTOMATICS of AGROINDUSTRIAL PRODUCTION of the NATIONAL ACADEMY of AGRARIAN SCIENCES of UKRAINE
Published: October 2024

Purpose. Creation and introduction into production of combined implements for vertical tillage Methods. Analytical, experimental, research and development. Results. A combined implements for vertical tillage has been developed and put into production. Conclusions. Two models of combined implements DCh-4.5 and DCh-3.0 have been developed for simultaneous shallow tillage to a depth of 12 cm and basic vertical tillage to a depth of 35 cm, which have a working width of 4.5 and 3.0 m. The DCh-4.5 model has been tested and is being manufactured for sale. Keywords: tools, soil, combined vertical tillage.
Strategi Layanan Bimbingan dan Konseling di Forum Komunikasi Disabilitas Kudus (FKDK)
Authors: Zulfa Amara
Published: October 2024

Disabilitas atau difabel merupakan pengindonesiaan dari akronim “differently able people”, yakni diff-able. Maknanya adalah orang yang mampu dengan cara yang berbeda. Tujuan Penelitian ini adalah untuk mengetahui strategi layanan bimbingan dan konseling di Forum Komunikasi Disabilitas Kudus (FKDK). Peneliti berfokus pada layanan bimbingan dan konseling dengan menggali secara dalam dari kasus yang ada di lokasi penelitian. Penelitian ini bersifat deskriptif kualitatif dengan fokus berdasarkan teori strategi pemberdayaan yaitu: layanan dasar, layanan responsive, dn layanan kolaborasi. Setiap manusia yang lahir tidak serupa ada yang normal dan bahkan ada yang tidak normal. Salah satunya adalah disabilitas. Penyandang disabilitas itu sendiri merupakan cacat fisik dan mental yang dialami seseorang karena ketidak sempurnaan perkembangan otak. Akibatnya banyak sekali sisi negatif yang mereka rasakan dari pencemooh, dikucilkan, diasingkan, dihina, dilecehkan dan lain sebagainya. Penyandang disabilitas juga merupakan ciptaan Tuhan sehingga dalam kehidupannya, mereka berhak mendapat kehidupan dan pekerjaan yang layak. Maka dari itu sangat penting sekali peran pemerintah dalam memberikan perhatian lebih guna kelangsungan hidup mereka dari Pendidikan, kesehatan dan lain sebagainya.
Kata Kunci : Strategi, Bimbingan, Konseling, Disabilitas, Difabel
A vigasz három variánsa
Authors: Arató László
Published: October 2024

My paper is basically methodological, I use comparative poem analysis strategies to read Mihály Babits’s three poems: “Zsoltár férfihangra” (“Psalm for Male Voice”), “Tremolo” (“Tremolo”), and “Csak posta voltál” (“You Were Just a Letter”). The ostensible clearly the narrator himself, thus all three poems can be understood as lyric addresses. On the other hand, the approaches of the three poems are completely different: the “Psalm for Male Voice’s” is cosmological-anthropological, the “Tremolo’s” is psychological, and the “You Were Just a Letter’s” is personality theoretical-anthropological-ontological. The poems could be interpreted successfully by secondary students as well, since the lyric address poem trio is thematically close to the teenagers experiencing identity crisis: two of the poems (“Psalm for Male Voice” and “Tremolo”) offer opportunities for self-asserting and comfort, the third one (“You Were Just a Letter”) stages the process of self-investigation and it explores the great question of teen age: “Who am I?”.
Japanin Boshin-sodan 1868–1869 historiankirjoituksen ja -esitysten kehitys
Authors: Sava Ville
Published: October 2024

Tämän tekstin tavoitteena on tarjota katsaus japanilaiseen Boshin-sodan historiankirjoitukseen ja -esityksiin, sekä sen muistamiseen liittyviä kiistakysymyksiä. Boshin-sota oli entisen Tokugawa-shogunaatin ja keisari Meijin ympärille muodostetun uuden hallituksen joukkojen välillä vuosina 1868—1869 käyty sisällissota, joka päätti Tokugawojen 265-vuotisen valtakauden. Sota oli merkittävä osa tapahtumaketjua, jonka myötä Japani muuttui noin neljässäkymmenessä vuodessa hajautetusti hallitusta feodaaliläänien kokoelmasta perustuslailliseksi yhtenäisvaltioksi ja alueelliseksi suurvallaksi. Vaikka sodan päättymisestä on kulunut yli 150 vuotta, siihen liittyvät kiistakysymykset, kuten kaatuneiden muistaminen, osapuolista käytettävät termit sekä sodan eskalaation syyt ovat säilyneet kiistanalaisena. Tulkinnat sodasta ovat myös muuttuneet ajan saatossa. Tämän japanilaisen sisällissodan historiankirjoituksen ja muistamisen tarkastelu Japanin ulkopuolella tarjoaa myös uusia näkökulmia laajempaan sisällissotien muistamisen kontekstiin.
Ensimmäisen maailmansodan sairaanhoitajien työskentely ja traumat minisarjoissa ja elokuvissa
Authors: Hiltunen Taneli
Published: October 2024

Tässä näkökulma-artikkelissa tarkastellaan ensimmäisen maailmansodan britti- ja australialaisten sairaanhoitajien kokemusten ja niiden jättämien traumojen kuvaamista kolmessa televisiominisarjassa ja yhdessä elokuvassa. Kolme niistä valmistui ensimmäisen maailmansodan syttymisen sadantena muistovuonna 2014, ja kaikki ovat naisten käsikirjoittamia. Yhdessä ne avaavat fiktiotuotannoissa vähemmän esillä ollutta puolta naisten rooleista ja ammattitaidosta vuosien 1914–1918 koettelevien ja alati muuttuvien olosuhteiden keskellä sekä toisaalta selviytymiskeinoja sodanjälkeisessäkin maailmassa.
Correlation of Sex BMI with Fusion of Human Sternum in ‘Bengalee’ Population from Dead Bodies Sent for Autopsy in NRSMCH Morgue
Authors: Sovan Dutta Sayak , Mukhopadhyay Sandip , Adhikary Subhajit
Published: October 2024

Background: Sternum is the bone which gives a fair idea for the estimation of age in the later decadesof life. It is a well established fact that factors like endocrinal, heredity, climate, diatic habits have certaindegree of influence over bony union and it is also proved that epiphyseal union occurs one to two yearsearlier in females than in males. BMI (Body Mass Index) is defined as person’s weight in kilograms dividedby the square of height in meters. Methods: The aim of the study is to establish any Correlation of sex andBMI with the fusion of different parts of Sternum in Bengalees.120 sternums are studied in this study overa period of 1.5 years from the dead bodies of ‘Bengalee’ persons sent for Post Mortem examination in theHospital morgue, Department of Forensic Medicine & Toxicology, N.R.S Medical College & Hospital,Kolkata. Concussion: There was no significant difference between male and female in respect to the agesshowing fusion. When the BMI of the subjects were compared with different grades of fusion between thesternal segments, significant statistical correlation was found between the fusion of sternebrae and the BMI,but fusion of Xiphisternum and Manubrium with Mesosternum did not show any statistically significantcorrelation. Sexual variation of ages for fusion of sternum was not found in ‘Bengalee’ population. Nutritionalstatus has a significant effect on the fusion of the sternebrae with each other, but no significant effect on thefusion of xiphisternum and manubrium with body of sternum.
Emergency Traumatic Patients, Study Analysis in Nineveh Province in Iraq
Authors: Mohammed Salih Abdullah Ali  , Zainab Saud Abdulaziz  , Sara Raad Lahoob  , Azzawi M Hadi
Published: October 2024

Background: Trauma is the medical problems associated with physical injury. Physical injuries includ thermal, chemical and ionizing radiation but mechanical injury is the most common type. The study was aimed to highlight the epidemiological parameters of these cases, determine most common causes and the management as well outcome for them. Patients and Methods: This was a cross section study involve 250 trauma cases admitted to Alsalam and Aljumhoory teaching hospitals of Nineveh province Iraq, from November 2018 to April 2019. Results: Males are more affected than females, and 56 % of patients belong to the age groups from 10 to 39 years, we found that Slips and falls (or same level falls) are the most common mechanism of injury specially among elderly people, while bullet and blast injuries form a small percentage of injuries with 4% & 1.6% respectively. Limb injury is the most common type of injury, followed by head injuries. Most of these injuries were treated conservatively but about quarter of them require surgery, while abdominal injuries which represent about 5.6% of all injuries, were treated by surgery with exception of 21.4% treated conservatively. Conclusion: Young males are more exposed to trauma. Limb injury is the most common type of injury while head injury is the commonest cause of death. Conservative treatment is the most used strategy. Bowel is the most intra-abdominal organ affected