bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Welding Parameters on Strength and Corrosion Behavior of Dissimilar Galvanized Q&P and TRIP Spot Welds
Authors: Russo Spena Pasquale , Rossi Stefano , Wurzer Rudi
Published: December 2017

This study investigates the effects of the main welding parameters on mechanical strength and corrosion behavior of galvanized quenching and partitioning and transformation induced plasticity spot welds, which are proposed to assemble advanced structural car elements for the automotive industry. Steel sheets have been welded with different current, clamping force, and welding time settings. The quality of the spot welds has been assessed through lap-shear and salt spray corrosion tests, also evaluating the effects of metal expulsion on strength and corrosion resistance of the joints. An energy dispersive spectrometry elemental mapping has been used to assess the damage of the galvanized zinc coating and the nature of the corrosive products. Welding current and time have the strongest influence on the shear strength of the spot welds, whereas clamping force is of minor importance. However, clamping force has the primary effect on avoiding expulsion of molten metal from the nugget during the joining process. Furthermore, clamping force has a beneficial influence on the corrosion resistance because it mainly hinders the permeation of the corrosive environment towards the spot welds. Although the welded samples can exhibit high shear strength also when a metal expulsion occurs, this phenomenon should be avoided because it enhances the damage and vaporization of the protective zinc coating.
Microstructural, Mechanical, and Electrochemical Analysis of Duplex and Superduplex Stainless Steels Welded with the Autogenous TIG Process Using Different Heat Input
Authors: Da Fonseca Gláucio Soares , Barbosa Luis Otavio Rodrigues , Ferreira Elivelton Alves , Xavier Carlos Roberto , De Castro José Adilson
Published: December 2017

Duplex Stainless Steels (DSS) and Superduplex Stainless Steels (SDSS) have a strong appeal in the petrochemical industry. These steels have excellent properties, such as corrosion resistance and good toughness besides good weldability. Welding techniques take into account the loss of alloying elements during the process, so this loss is usually compensated by the addition of a filler metal rich in alloying elements. A possible problem would be during the welding of these materials in adverse conditions in service, where the operator could have difficulties in welding with the filler metal. Therefore, in this work, two DSS and one SDSS were welded, by autogenous Tungsten Inert Gas (TIG), i.e., without addition of a filler metal, by three different heat inputs. After welding, microstructural, mechanical, and electrochemical analysis was performed. The microstructures were characterized for each welding condition, with the aid of optical microscopy (OM). Vickers hardness, Charpy-V, and cyclic polarization tests were also performed. After the electrochemical tests, the samples were analyzed by scanning electron microscopy (SEM). The SDSS welded with high heat input kept the balance of the austenite and ferrite, and toughness above the limit value. The hardness values remain constant in the weld regions and SDSS is the most resistant to corrosion.
Rotating Circular Micro-Platform with Integrated Waveguides and Latching Arm for Reconfigurable Integrated Optics
Authors: Briere Jonathan , Elsayed Mohannad , Saidani Menouer , Bérard Martin , Beaulieu Philippe-Olivier , Rabbani-Haghighi Hadi , Nabki Frederic , Ménard Michaël
Published: December 2017

This work presents a laterally rotating micromachined platform integrated under optical waveguides to control the in-plane propagation direction of light within a die to select one of multiple outputs. The platform is designed to exhibit low constant optical losses throughout the motion range and is actuated electrostatically using an optimized circular comb drive. An angular motion of ±9.5° using 180 V is demonstrated. To minimize the optical losses between the moving and fixed parts, a gap-closing mechanism is implemented to reduce the initial air gap to submicron values. A latch structure is implemented to hold the platform in place with a resolution of 0.25° over the entire motion range. The platform was integrated with silicon nitride waveguides to create a crossbar switch and preliminary optical measurements are reported. In the bar state, the loss was measured to be 14.8 dB with the gap closed whereas in the cross state it was 12.2 dB. To the authors’ knowledge, this is the first optical switch based on a rotating microelectromechanical device with integrated silicon nitride waveguides reported to date.
Abundance, Distribution, and Modes of Occurrence of Uranium in Chinese Coals
Authors: Chen Jian , Chen Ping , Yao Duoxi , Huang Wenhui , Tang Shuheng , Wang Kejian , Liu Wenzhong , Hu Youbiao , Zhang Bofei , Sha Jidun
Published: December 2017

Due to its environmental and resource impacts, the geochemistry of uranium in coal is of both academic and practical significance. In order to give a comprehensive summary about the geochemistry of uranium in coals, the abundance, distribution, and modes of occurrence of uranium in Chinese coals were reviewed in this paper. Although some coals from southwestern and northwestern China are significantly enriched in uranium, the common Chinese coals are of a comparable uranium concentration to the world coals. The roof and floor rocks, and parting of coalbeds, or coal benches that are close to the surrounding rock are favorable hosts for uranium in one coalbed. The uranium concentrations in coals of different ages decrease in this order, e.g., Paleogene and Neogene > Late Permian > Late Triassic > Late Carboniferous and Early Permian > Late Jurassic and Early Cretaceous > Early and Middle Jurassic. Uranium in Chinese coals is mainly associated with organic matter, and is correspondingly enriched in subbituminous coal and lignite.
Multi Component Reactions under Increased Pressure: On the Mechanism of Formation of Pyridazino[5,4,3-de][1,6]naphthyridine Derivatives by the Reaction of Malononitrile, Aldehydes and 2-Oxoglyoxalarylhydrazones in Q-Tubes
Authors: AL-Johani Majdah , Al-Zaydi Khadijah , Mousally Sameera , Alqahtani Norah , Elnagdi Noha , Elnagdi Mohamed
Published: December 2017

Efficient synthesis of phenanthridin-6(5H)-one derivatives 12a–n in a four-component reaction of aldehyde hydrazone, aromatic aldehydes and malononitrile in Q-Tubes is reported. The results showed that the methodology has the advantage of being a one-pot synthesis of tricyclic systems in good yields. Potential routes leading to formation of compounds 12 are discussed. The structures of the synthesized compounds could be unequivocally established via X-ray crystal structure determination and spectroscopic methods.
Melatonin Pharmacokinetics Following Oral Administration in Preterm Neonates
Authors: Carloni Silvia , Proietti Fabrizio , Rocchi Marco , Longini Mariangela , Marseglia Lucia , D’Angelo Gabriella , Balduini Walter , Gitto Eloisa , Buonocore Giuseppe
Published: December 2017

Melatonin possesses potential efficacy in perinatal brain injuries, and has been proposed as adjunctive pharmacological therapy in combination with hypothermia in the clinical setting. However, the pharmacokinetics of melatonin in preterm and term newborns is still unknown. The aim of this study was to analyze the pharmacokinetics of melatonin after intragastric administration in preterm infants. Preterm newborns were enrolled 24–72 h after birth, and randomly assigned to three groups receiving a single bolus of 0.5 mg·kg−1 melatonin, or 3 boluses of 1 or 5 mg·kg−1 of melatonin at 24-h intervals. Blood samples were collected before and at selective times after melatonin administration. The half-life of melatonin in plasma ranged from 7.98 to 10.94 h, and the area under the curve (AUC) from 10.48 to 118.17 µg·mL−1·h−1. Our results indicate a different pharmacokinetic profile in premature newborns, compared to adults and experimental animals. The high peak plasma concentrations and the long half-life indicate that in the neonatal clinical setting, it is possible to obtain and maintain high serum concentrations using a single administration of melatonin repeated every 12/24 h.
A Facile Approach to Tune the Electrical and Thermal Properties of Graphene Aerogels by Including Bulk MoS2
Authors: Gong Feng , Liu Xiongxiong , Yang Yunlong , Xia Dawei , Wang Wenbin , Duong Hai , Papavassiliou Dimitrios , Xu Ziqiang , Liao Jiaxuan , Wu Mengqiang
Published: December 2017

Graphene aerogels (GAs) have attracted extensive interest in diverse fields, owing to their ultrahigh surface area, low density and decent electrical conductivity. However, the undesirable thermal conductivity of GAs may limit their applications in energy storage devices. Here, we report a facile hydrothermal method to modulate both the electrical and thermal properties of GAs by including bulk molybdenum disulfide (MoS2). It was found that MoS2 can help to reduce the size of graphene sheets and improve their dispersion, leading to the uniform porous micro-structure of GAs. The electrical measurement showed that the electrical conductivity of GAs could be decreased by 87% by adding 0.132 vol % of MoS2. On the contrary, the thermal conductivity of GAs could be increased by ~51% by including 0.2 vol % of MoS2. The quantitative investigation demonstrated that the effective medium theories (EMTs) could be applied to predict the thermal conductivity of composite GAs. Our findings indicated that the electrical and thermal properties of GAs can be tuned for the applications in various fields.
Exploring the Impact of Food on the Gut Ecosystem Based on the Combination of Machine Learning and Network Visualization
Authors: Shima Hideaki , Masuda Shizuka , Date Yasuhiro , Shino Amiu , Tsuboi Yuuri , Kajikawa Mizuho , Inoue Yoshihiro , Kanamoto Taisei , Kikuchi Jun
Published: December 2017

Prebiotics and probiotics strongly impact the gut ecosystem by changing the composition and/or metabolism of the microbiota to improve the health of the host. However, the composition of the microbiota constantly changes due to the intake of daily diet. This shift in the microbiota composition has a considerable impact; however, non-pre/probiotic foods that have a low impact are ignored because of the lack of a highly sensitive evaluation method. We performed comprehensive acquisition of data using existing measurements (nuclear magnetic resonance, next-generation DNA sequencing, and inductively coupled plasma-optical emission spectroscopy) and analyses based on a combination of machine learning and network visualization, which extracted important factors by the Random Forest approach, and applied these factors to a network module. We used two pteridophytes, Pteridium aquilinum and Matteuccia struthiopteris, for the representative daily diet. This novel analytical method could detect the impact of a small but significant shift associated with Matteuccia struthiopteris but not Pteridium aquilinum intake, using the functional network module. In this study, we proposed a novel method that is useful to explore a new valuable food to improve the health of the host as pre/probiotics.
Functional Foods and Lifestyle Approaches for Diabetes Prevention and Management
Authors: Alkhatib Ahmad , Tsang Catherine , Tiss Ali , Bahorun Theeshan , Arefanian Hossein , Barake Roula , Khadir Abdelkrim , Tuomilehto Jaakko
Published: December 2017

Functional foods contain biologically active ingredients associated with physiological health benefits for preventing and managing chronic diseases, such as type 2 diabetes mellitus (T2DM). A regular consumption of functional foods may be associated with enhanced anti-oxidant, anti-inflammatory, insulin sensitivity, and anti-cholesterol functions, which are considered integral to prevent and manage T2DM. Components of the Mediterranean diet (MD)—such as fruits, vegetables, oily fish, olive oil, and tree nuts—serve as a model for functional foods based on their natural contents of nutraceuticals, including polyphenols, terpenoids, flavonoids, alkaloids, sterols, pigments, and unsaturated fatty acids. Polyphenols within MD and polyphenol-rich herbs—such as coffee, green tea, black tea, and yerba maté—have shown clinically-meaningful benefits on metabolic and microvascular activities, cholesterol and fasting glucose lowering, and anti-inflammation and anti-oxidation in high-risk and T2DM patients. However, combining exercise with functional food consumption can trigger and augment several metabolic and cardiovascular protective benefits, but it is under-investigated in people with T2DM and bariatric surgery patients. Detecting functional food benefits can now rely on an “omics” biological profiling of individuals’ molecular, genetics, transcriptomics, proteomics, and metabolomics, but is under-investigated in multi-component interventions. A personalized approach for preventing and managing T2DM should consider biological and behavioral models, and embed nutrition education as part of lifestyle diabetes prevention studies. Functional foods may provide additional benefits in such an approach.
Liposomal and Deoxycholate Amphotericin B Formulations: Effectiveness against Biofilm Infections of Candida spp.
Authors: Rodrigues Célia , Henriques Mariana
Published: December 2017

Background: candidiasis is the primary fungal infection encountered in patients undergoing prolonged hospitalization, and the fourth leading cause of nosocomial bloodstream infections. One of the most important Candida spp. virulence factors is the ability to form biofilms, which are extremely refractory to antimicrobial therapy and very difficult to treat with the traditional antifungal therapies. It is known that the prophylaxis or treatment of a systemic candidiasis are recurrently taken without considering the possibility of a Candida spp. biofilm-related infections. Therefore, it is important to assess the effectiveness of the available drugs and which formulations have the best performance in these specific infections. Methods: 24-h-biofilms of four Candida spp. and their response to two amphotericin B (AmB) pharmaceutical formulations (liposomal and deoxycholate) were evaluated. Results: generally, Candida glabrata was the less susceptible yeast species to both AmBs. MBECs revealed that it is therapeutically more appealing to use AmB-L than AmB-Deox for all Candida spp. biofilms, since none of the determined concentrations of AmB-L reached 10% of the maximum daily dose, but both formulations showed a very good capacity in the biomass reduction. Conclusions: the liposomal formulation presents better performance in the eradication of the biofilm cells for all the species in comparison with the deoxycholate formulation.
What Is Our Current Understanding of PrPSc-Associated Neurotoxicity and Its Molecular Underpinnings?
Authors: Hughes Daniel , Halliday Mark
Published: December 2017

The prion diseases are a collection of fatal, transmissible neurodegenerative diseases that cause rapid onset dementia and ultimately death. Uniquely, the infectious agent is a misfolded form of the endogenous cellular prion protein, termed PrPSc. Despite the identity of the molecular agent remaining the same, PrPSc can cause a range of diseases with hereditary, spontaneous or iatrogenic aetiologies. However, the link between PrPSc and toxicity is complex, with subclinical cases of prion disease discovered, and prion neurodegeneration without obvious PrPSc deposition. The toxic mechanisms by which PrPSc causes the extensive neuropathology are still poorly understood, although recent advances are beginning to unravel the molecular underpinnings, including oxidative stress, disruption of proteostasis and induction of the unfolded protein response. This review will discuss the diseases caused by PrPSc toxicity, the nature of the toxicity of PrPSc, and our current understanding of the downstream toxic signaling events triggered by the presence of PrPSc.
Convolutional Neural Network based Estimation of Gel-like Food Texture by a Robotic Sensing System
Authors: Shibata Akihide , Ikegami Akira , Nakauma Makoto , Higashimori Mitsuru
Published: December 2017

This paper presents a robotic sensing system that evaluates the texture of gel-like food, in which not only mechanical characteristics, but also geometrical characteristics of the texture are objectively and quantitatively evaluated. When a human chews a gel-like food, the person perceives the changes in the shape and contact force simultaneously on the tongue. Based on their impression, they evaluate the texture. To reproduce this procedure using a simple artificial mastication robot, the pressure distribution of the gel-like food is measured, and the information associated with both the geometrical and mechanical characteristics is simultaneously acquired. The relationship between the value of the human sensory evaluation of the texture and the pressure distribution image is then modeled by applying a convolutional neural network. Experimental results show that the proposed system succeeds in estimating the values of a human sensory evaluation for 23 types of gel-like food with a coefficient of determination greater than 0.92.
Validation of Satellite Rainfall Products over a Mountainous Watershed in a Humid Subtropical Climate Region of Brazil
Authors: Dos Reis João , Rennó Camilo , Lopes Eymar
Published: December 2017

Remote sensing allows for the continuous and repetitive measurement of rainfall values. Satellite rainfall products such as Tropical Rainfall Measurement Mission (TRMM) 3B42 and the Hydroestimator (Hydroe) can be potential sources of data for hydrologic applications, mainly in areas with irregular and sparse spatial distributions of traditional rain gauge stations. However, the accuracy of these satellite rainfall products over different spatial and temporal scales is unknown. In this study, we examined the potential of the TRMM 3B42 and Hydroe rainfall products to provide reliable rainfall estimates for a mountainous watershed in a humid subtropical climate region of Brazil. The purpose was to develop useful guidelines for future hydrologic studies on the potential and uncertainties of the rainfall products at different spatial and temporal resolutions. We compared the satellite products to reference rainfall data collected at 11 rain gauge stations irregularly distributed in the area. The results showed different levels of accuracy for each temporal scale evaluated. TRMM 3B42 performed better at the daily, monthly, and seasonal scales than Hydroe, while Hydroe presented a better correlation at the annual scale. In general, TRMM 3B42 overestimated the rainfall over the watershed at all evaluated temporal scales, whereas Hydroe underestimated it except for June–August at the seasonal scale. An evaluation based on contingency tables indicated that TRM 3B42 was better able to represent the local rainfall than Hydroe. The findings of this study indicate that satellite rainfall products are better suited for applications at the monthly and annual scales rather than the daily scale.
Evaluation of Seed Emergence Uniformity of Mechanically Sown Wheat with UAV RGB Imagery
Authors: Liu Tao , Li Rui , Jin Xiuliang , Ding Jinfeng , Zhu Xinkai , Sun Chengming , Guo Wenshan
Published: December 2017

The uniformity of wheat seed emergence is an important characteristic used to evaluate cultivars, cultivation mode and field management. Currently, researchers typically investigated the uniformity of seed emergence by manual measurement, a time-consuming and laborious process. This study employed field RGB images from unmanned aerial vehicles (UAVs) to obtain information related to the uniformity of wheat seed emergence and missing seedlings. The calculation of the length of areas with missing seedlings in both drill and broadcast sowing can be achieved by using an area localization algorithm, which facilitated the comprehensive evaluation of uniformity of seed emergence. Through a comparison between UAV images and the results of manual surveys used to gather data on the uniformity of seed emergence, the root-mean-square error (RMSE) was 0.44 for broadcast sowing and 0.64 for drill sowing. The RMSEs of the numbers of missing seedling regions for broadcast and drill sowing were 1.39 and 3.99, respectively. The RMSEs of the lengths of the missing seedling regions were 12.39 cm for drill sowing and 0.20 cm2 for broadcast sowing. The UAV image-based method provided a new and greatly improved method for efficiently measuring the uniformity of wheat seed emergence. The proposed method could provide a guideline for the intelligent evaluation of the uniformity of wheat seed emergence.
Local Deep Hashing Matching of Aerial Images Based on Relative Distance and Absolute Distance Constraints
Authors: Chen Suting , Li Xin , Zhang Yanyan , Feng Rui , Zhang Chuang
Published: December 2017

Aerial images have features of high resolution, complex background, and usually require large amounts of calculation, however, most algorithms used in matching of aerial images adopt the shallow hand-crafted features expressed as floating-point descriptors (e.g., SIFT (Scale-invariant Feature Transform), SURF (Speeded Up Robust Features)), which may suffer from poor matching speed and are not well represented in the literature. Here, we propose a novel Local Deep Hashing Matching (LDHM) method for matching of aerial images with large size and with lower complexity or fast matching speed. The basic idea of the proposed algorithm is to utilize the deep network model in the local area of the aerial images, and study the local features, as well as the hash function of the images. Firstly, according to the course overlap rate of aerial images, the algorithm extracts the local areas for matching to avoid the processing of redundant information. Secondly, a triplet network structure is proposed to mine the deep features of the patches of the local image, and the learned features are imported to the hash layer, thus obtaining the representation of a binary hash code. Thirdly, the constraints of the positive samples to the absolute distance are added on the basis of the triplet loss, a new objective function is constructed to optimize the parameters of the network and enhance the discriminating capabilities of image patch features. Finally, the obtained deep hash code of each image patch is used for the similarity comparison of the image patches in the Hamming space to complete the matching of aerial images. The proposed LDHM algorithm evaluates the UltraCam-D dataset and a set of actual aerial images, simulation result demonstrates that it may significantly outperform the state-of-the-art algorithm in terms of the efficiency and performance.
Barest Pixel Composite for Agricultural Areas Using Landsat Time Series
Authors: Diek Sanne , Fornallaz Fabio , Schaepman Michael E. , De Jong Rogier
Published: December 2017

Many soil remote sensing applications rely on narrow-band observations to exploit molecular absorption features. However, broadband sensors are invaluable for soil surveying, agriculture, land management and mineral exploration, amongst others. These sensors provide denser time series compared to high-resolution airborne imaging spectrometers and hold the potential of increasing the observable bare-soil area at the cost of spectral detail. The wealth of data coming along with these applications can be handled using cloud-based processing platforms such as Earth Engine. We present a method for identifying the least-vegetated observation, or so called barest pixel, in a dense time series between January 1985 and March 2017, based on Landsat 5, 7 and 8 observations. We derived a Barest Pixel Composite and Bare Soil Composite for the agricultural area of the Swiss Plateau. We analysed the available data over time and concluded that about five years of Landsat data were needed for a full-coverage composite (90% of the maximum bare soil area). Using the Swiss harmonised soil data, we derived soil properties (sand, silt, clay, and soil organic matter percentages) and discuss the contribution of these soil property maps to existing conventional and digital soil maps. Both products demonstrate the substantial potential of Landsat time series for digital soil mapping, as well as for land management applications and policy making.
Matching Multi-Source Optical Satellite Imagery Exploiting a Multi-Stage Approach
Authors: Liu Yuxuan , Mo Fan , Tao Pengjie
Published: December 2017

Geometric distortions and intensity differences always exist in multi-source optical satellite imagery, seriously reducing the similarity between images, making it difficult to obtain adequate, accurate, stable, and well-distributed matches for image registration. With the goal of solving these problems, an effective image matching method is presented in this study for multi-source optical satellite imagery. The proposed method includes three steps: feature extraction, initial matching, and matching propagation. Firstly, a uniform robust scale invariant feature transform (UR-SIFT) detector was used to extract adequate and well-distributed feature points. Secondly, initial matching was conducted based on the Euclidean distance to obtain a few correct matches and the initial projective transformation between the image pair. Finally, two matching strategies were used to propagate matches and produce more reliable matching results. By using the geometric relationship between the image pair, geometric correspondence matching found more matches than the initial UR-SIFT feature points. Further probability relaxation matching propagated some new matches around the initial UR-SIFT feature points. Comprehensive experiments on Chinese ZY3 and GaoFen (GF) satellite images revealed that the proposed algorithm performs well in terms of the number of correct matches, correct matching rate, spatial distribution, and matching accuracy, compared to the standard UR-SIFT and triangulation-based propagation method.
Assessment of GF-3 Polarimetric SAR Data for Physical Scattering Mechanism Analysis and Terrain Classification
Authors: Yin Junjun , Yang Jian , Zhang Qingjun
Published: December 2017

On 10 August 2016 China launched the GF-3, its first C-band polarimetric synthetic aperture radar (SAR) satellite, which was put into operation at the end of January, 2017. GF-3 polarimetric SAR has many advantages such as high resolution and multi-polarization imaging capabilities. Polarimetric SAR can fully characterize the backscatter property of targets, and thus it is of great interest to explore the physical scattering mechanisms of terrain types, which is very important in interpreting polarimetric SAR imagery and for its further usages in Earth observations. In this paper, focusing on target scattering characterization and feature extraction, we generalize the Δ α B / α B method, which was proposed under the reflection symmetric assumption, for the general backscatter process to account for both the reflection symmetry and asymmetry cases. Then, we evaluate the performances of physical scattering mechanism analysis methods for GF-3 polarimetric SAR imagery. Radarsat-2 data acquired over the same area is used for cross validation. Results show that GF-3 polarimetric SAR data has great potential for target characterization, especially for ocean area observation.
Recent Trends in Microextraction Techniques Employed in Analytical and Bioanalytical Sample Preparation
Authors: Kabir Abuzar , Locatelli Marcello , Ulusoy Halil
Published: December 2017

Sample preparation has been recognized as a major step in the chemical analysis workflow. As such, substantial efforts have been made in recent years to simplify the overall sample preparation process. Major focusses of these efforts have included miniaturization of the extraction device; minimizing/eliminating toxic and hazardous organic solvent consumption; eliminating sample pre-treatment and post-treatment steps; reducing the sample volume requirement; reducing extraction equilibrium time, maximizing extraction efficiency etc. All these improved attributes are congruent with the Green Analytical Chemistry (GAC) principles. Classical sample preparation techniques such as solid phase extraction (SPE) and liquid-liquid extraction (LLE) are being rapidly replaced with emerging miniaturized and environmentally friendly techniques such as Solid Phase Micro Extraction (SPME), Stir bar Sorptive Extraction (SBSE), Micro Extraction by Packed Sorbent (MEPS), Fabric Phase Sorptive Extraction (FPSE), and Dispersive Liquid-Liquid Micro Extraction (DLLME). In addition to the development of many new generic extraction sorbents in recent years, a large number of molecularly imprinted polymers (MIPs) created using different template molecules have also enriched the large cache of microextraction sorbents. Application of nanoparticles as high-performance extraction sorbents has undoubtedly elevated the extraction efficiency and method sensitivity of modern chromatographic analyses to a new level. Combining magnetic nanoparticles with many microextraction sorbents has opened up new possibilities to extract target analytes from sample matrices containing high volumes of matrix interferents. The aim of the current review is to critically audit the progress of microextraction techniques in recent years, which has indisputably transformed the analytical chemistry practices, from biological and therapeutic drug monitoring to the environmental field; from foods to phyto-pharmaceutical applications.
Effects of Iron Amendments on the Speciation of Arsenic in the Rice Rhizosphere after Drainage
Authors: Yamaguchi Noriko , Ohkura Toshiaki , Hikono Atsuko , Yamaguchi Hiroshi , Hashimoto Yohey , Makino Tomoyuki
Published: December 2017

Applications of iron- (Fe-) bearing materials represent an effective countermeasure for decreasing the dissolution of arsenic (As) in soil under anaerobic conditions. In this study, we investigated the effects of Fe amendments (ferrihydrite-based and zero-valent iron- (ZVI-) based materials) on the speciation of As in rice cultivated soils and root-attached materials including Fe plaque when the soil shifts from anaerobic to aerobic conditions. Rice (Oryza sativa L.) was cultivated in pots filled with soil under continuous flooding conditions, and root distribution in the soil was restricted inside a cylinder made by nylon mesh. Soil and root samples were collected after drainage at different growth stages of the rice plants, which are represented by intermittent drainage and drainage at harvest. The speciation of As was determined by As K-edge X-ray absorption near edge structure (XANES) spectroscopy. The proportion of arsenite did not differ between the bulk soil and root-attached materials including Fe plaque, whereas a larger proportion of dimethylarsinic acid was found in the root-attached materials regardless of the application of Fe amendments. Observation of soil thin-sections showed that the application of Fe amendments caused an increase in Fe (hydr)oxide deposition around the roots as well as on the soil particles. In addition to Fe (hydr)oxide, sulfide was found to be associated with As under anaerobic conditions, notably for the ZVI-amended soil at the time of intermittent drainage. The concentration of As in the soil solution and As uptake by rice grains decreased, while As speciation near the roots was not influenced by the application of Fe amendments. In conclusion, Fe amendments mitigated As dissolution in the soil solution by providing a sorption site for As in bulk soil without altering As speciation near the roots.
Interrepetition Rest Set Lacks the V-Shape Systolic Pressure Response Advantage during Resistance Exercise
Authors: Mayo Xian , Iglesias-Soler Eliseo , Kingsley J. , Dopico Xurxo
Published: December 2017

Resistance exercise may lead to an aneurysm due to dangerous levels of systemic hypertension. Thus, a minimized pressure response during exercise may guarantee safer training. For that, we analyzed an interrepetition rest design (IRD) hypothesizing that it would produce a lower systolic blood pressure (SBP) response in comparison with a continuous design (CD). Additionally, we studied the effect of accumulated repetitions on the increasing SBP rate during the first continuous set. Fifteen healthy participants (age: 24 ± 2 years; SBP: 113 ± 8 mmHg) performed leg presses, with 40 repetitions and 720 s of total rest, structured in an IRD of individual repetitions (resting time: 18.5 s), and in a CD of five sets of eight repetitions (resting time: 180 s). Analyses reported an increase (p = 0.013) in the mean peaks of SBP in the IRD (162 ± 21 mmHg), versus the CD (148 ± 19 mmHg), while both augmented versus baselines (p < 0.001). Additionally, the linear model estimated a progressive increase of SBP of around 7 mmHg per repetition. Summarily, the IRD produced a higher mean of the SBP peaks during the 40 repetitions due to lacking the v-shape advantage in comparison with the CD.
Value-Added-Based Accounting of CO2 Emissions: A Multi-Regional Input-Output Approach
Authors: Liu Hongguang , Fan Xiaomei
Published: December 2017

In the era of globalization and international trade, the production-based CO2 emissions accounting system, proposed by United Nations Framework Convention on Climate Change, can easily lead to a “carbon leakage” issue. Thus, the accounting of consumption-based carbon emissions and carbon emissions embodied in international trade has received considerable research attention. Nevertheless, researchers also indicated that the consumption-based principle has some weaknesses, for example, it leads the producers inert on reducing carbon emissions while gaining economic benefits. To share carbon emissions responsibilities between producers and consumers is widely recognized. So, setting an income-based emissions accounting method as to producer is a necessary complement for accounting national carbon emissions. This study promoted a model, called the value-added-based accounting of CO2 emissions method, to account for anthropogenic CO2 emissions within the context of the economic benefit principle. Based on the global multi-regional input-output table and national carbon emissions database, we calculated the national/regional carbon emissions based on the value-added accounting approach as well as the amount of global carbon emissions embodied in value-added chains. If the results are served as a supplement for calculating the amount of CO2 emissions reduction that a country is responsible for, problems such as carbon leakage and resistance to improving the energy efficiency of exporting sector may be solved, because all the supply chains emissions associated with the economic growth of a country would be considered.
An Advanced Sodium-Cooled Fast Reactor Core Concept Using Uranium-Free Metallic Fuels for Maximizing TRU Burning Rate
Authors: You Wuseong , Hong Ser
Published: December 2017

In this paper, we designed and analyzed advanced sodium-cooled fast reactor cores using uranium-free metallic fuels for maximizing burning rate of transuranics (TRU) nuclides from PWR spent fuels. It is well known that the removal of fertile nuclides such as 238U from fuels in liquid metal cooled fast reactor leads to the degradation of important safety parameters such as the Doppler coefficient, coolant void worth, and delayed neutron fraction. To resolve the degradation of the Doppler coefficient, we considered adding resonant nuclides to the uranium-free metallic fuels. The analysis results showed that the cores using uranium-free fuels loaded with tungsten instead of uranium have a significantly lower burnup reactivity swing and more negative Doppler coefficients than the core using uranium-free fuels without resonant nuclides. In addition, we considered the use of axially central B4C absorber region and moderator rods to further improve safety parameters such as sodium void worth, burnup reactivity swing, and the Doppler coefficient. The results of the analysis showed that the final design core can consume ~353 kg per cycle and satisfies self-controllability under unprotected accidents. The fuel cycle analysis showed that the PWR–SFR coupling fuel cycle option drastically reduces the amount of waste going to repository and the SFR burner can consume the amount of TRUs discharged from 3.72 PWRs generating the same electricity.
The Analysis of the Determinants of Sustainable Cross-Border Cooperation and Recommendations on Its Harmonization
Authors: Kurowska-Pysz Joanna , Szczepańska-Woszczyna Katarzyna
Published: December 2017

Cross-border partnerships are a distinctive example of inter-organizational cooperation, embedded, in terms of territory, in the neighboring borderland regions of two or more countries. The aim of this paper is to identify factors that contribute to the sustainable cross-border cooperation and affect motivation to increase cooperation between cross-border partners. The objective implementation is connected with the verification of a hypothesis referring to the possible impact of the European Union funds on the trans-boundary cooperation transformations. Results of desk research and quantitative research involving IDI, CATI, CAWI and CATI and PAPI data collection methods, implemented in the Polish–Czech borderland in 2016 were used in this paper. Research on the Polish–Lithuanian borderland was also used in the paper to conduct comparative analysis, useful to identify and evaluate factors motivating sustainable cross-border cooperation in the Czech–Polish borderland. The sustainable, cross-border and inter-organizational cooperation in the borderlands results from the simultaneous interaction of three groups of factors: (1) people and institutions (the quality of interpersonal relationships); (2) cross-border planning, procedures and support mechanisms (e.g., the possibility of jointly planning the cross-border cooperation and obtaining EU funds for the development of the borderlands as well as the availability of other funds helpful in this kind of cooperation); and (3) environment (historical affinity and geographical proximity of neighboring border regions, system support at the regional and local level in neighboring countries).
Evaluating the Environmental Consequences of Swedish Food Consumption and Dietary Choices
Authors: Martin Michael , Brandão Miguel
Published: December 2017

In recent years, a growing interest from consumers to know the origins and contents of foods has put alternative choices, such as organic foods and dietary changes, on the agenda. Dietary choices are important to address, as many studies find that activities related to food production account for nearly 20–30% of anthropogenic greenhouse gas (GHG) emissions. Nonetheless, while GHG emissions are important, often other environmental impact categories are not considered in the assessment of the sustainability of different foods, diets and choices. This study aims to quantify the implications of dietary choices for Swedish food consumption on a broad range of environmental impact categories using life cycle assessment to provide insight into the impacts, and potential tradeoffs, associated with certain food products and dietary choices. Scenarios are used to assess the implications of diets with reduced meat, increased Swedish food consumption, increased organic foods, vegan and semi-vegetarian diets. The results indicate that tradeoffs could be possible with certain dietary choices. Increasing Swedish food production and consumption may lead to lower impacts for all impact categories by reducing imports, although limitations in growing season and availability of foods in Sweden allows only for minor increases. The results also indicate that large reductions of greenhouse gas emissions are possible by reducing meat consumption, i.e., by halving meat consumption and through vegan and vegetarian diets. Nonetheless, an increase in vegetable, legume and fruit products may lead to a potential increase in human and ecosystem toxicity. Diets based on nutritional guidelines, show reductions in all impact categories, as these guidelines call for an increase in vegetables and fruits and a reduction in meat consumption. An increase in organic foods showed no significant change in climate impact, although toxicity potential was reduced significantly. Increasing consumption of organic foods may also lead to a reduction in biodiversity damage potential, and if all food is produced organically, it risks increasing eutrophication and land use.
Embryonic Ethanol Exposure Affects Early- and Late-Added Cardiac Precursors and Produces Long-Lasting Heart Chamber Defects in Zebrafish
Authors: Sarmah Swapnalee , Marrs James
Published: December 2017

Drinking mothers expose their fetuses to ethanol, which produces birth defects: craniofacial defects, cognitive impairment, sensorimotor disabilities and organ deformities, collectively termed as fetal alcohol spectrum disorder (FASD). Various congenital heart defects (CHDs) are present in FASD patients, but the mechanisms of alcohol-induced cardiogenesis defects are not completely understood. This study utilized zebrafish embryos and older larvae to understand FASD-associated CHDs. Ethanol-induced cardiac chamber defects initiated during embryonic cardiogenesis persisted in later zebrafish life. In addition, myocardial damage was recognizable in the ventricle of the larvae that were exposed to ethanol during embryogenesis. Our studies of the pathogenesis revealed that ethanol exposure delayed differentiation of first and second heart fields and reduced the number of early- and late-added cardiomyocytes in the heart. Ethanol exposure also reduced the number of endocardial cells. Together, this study showed that ethanol-induced heart defects were present in late-stage zebrafish larvae. Reduced numbers of cardiomyocytes partly accounts for the ethanol-induced zebrafish heart defects.
Evidence of Biomass Smoke Exposure as a Causative Factor for the Development of COPD
Authors: Capistrano Sarah , Van Reyk David , Chen Hui , Oliver Brian
Published: December 2017

Chronic obstructive pulmonary disease (COPD) is a progressive disease of the lungs characterised by chronic inflammation, obstruction of airways, and destruction of the parenchyma (emphysema). These changes gradually impair lung function and prevent normal breathing. In 2002, COPD was the fifth leading cause of death, and is estimated by the World Health Organisation (WHO) to become the third by 2020. Cigarette smokers are thought to be the most at risk of developing COPD. However, recent studies have shown that people with life-long exposure to biomass smoke are also at high risk of developing COPD. Most common in developing countries, biomass fuels such as wood and coal are used for cooking and heating indoors on a daily basis. Women and children have the highest amounts of exposures and are therefore more likely to develop the disease. Despite epidemiological studies providing evidence of the causative relationship between biomass smoke and COPD, there are still limited mechanistic studies on how biomass smoke causes, and contributes to the progression of COPD. This review will focus upon why biomass fuels are used, and their relationship to COPD. It will also suggest methodological approaches to model biomass exposure in vitro and in vivo.
Proteasome Inhibitor MG132 Enhances Cisplatin-Induced Apoptosis in Osteosarcoma Cells and Inhibits Tumor Growth
Authors: Sun Farui , Zhang Yuanjin , Xu Lijun , Li Songbai , Chen Xiang , Zhang Ling , Wu Yifan , Li Jun
Published: December 2017

Although cisplatin has been shown to be an integral part of chemotherapy regimen in osteosarcoma (OS) treatment, toxicity issues and chemoresistance have hindered therapeutic development for OS. Exploring novel combination therapy methods is needed to circumvent the limitations of cisplatin
alone. The proteasome inhibitor MG132 has shown antitumor effects in many solid tumors. However, little is known about its effects in combination with cisplatin in OS cells. In this study, we examined the effects of MG132 in combination with cisplatin in human OS cells (MG-63 and HOS). MG132
and cisplatin were applied to OS cells, respectively or jointly. The results demonstrated that MG132 markedly inhibited cell viability in a dose- and time-dependent manner, whereas viability of osteoblast cells was not affected, suggesting a selective toxicity of MG132 to cancerous cells.
Mechanistically, MG132 arrested cells in the G2/M phase in association with increased p21waf1 and induced cell apoptosis, which was accompanied by cleaved PARP. In addition to its apoptotic effect alone, MG132 significantly enhanced cisplatin-induced apoptosis in OS cells.
Furthermore, cell viability of the combined application of 10 μM MG132 and 5 μg/ml cisplatin was markedly inhibited compared to that of the individual application. These events were accompanied by the downregulation of NF-κB, mitochondrial antiapoptotic protein Bcl-xL, and PI3K/Akt,
which play a key role in cell survival. Finally, combination treatment of MG132 and cisplatin showed more antiproliferative effect than the single treatment in OS xenograft models. In summary, we concluded that MG132 interacted synergistically with cisplatin, which raised the possibility that combining the two drugs may represent a novel strategy in OS.
Binaural Interference in a Child: A Case Study
Authors: Schoepflin Janet R.
Published: December 2017

A case study of a child (KB) who demonstrated binaural interference is reported. KB wore unilateral amplification from 1.6 to 4.6 years of age, at which time word-recognition scores under phones were markedly asymmetric, reflecting significantly better performance for the aided ear
than the unaided ear, despite similar unaided pure-tone sensitivity. Suspecting the asymmetry in word-recognition performance might be the result of auditory deprivation, bilateral amplification was prescribed at 4.6 years of age. Three months later, adverse changes in the child's behavior
were reported. At 5.3 years, significant interaural asymmetry was noted in word-recognition scores under phones, in unilateral-aided word-recognition scores (90% vs. 36%), and in the bilateral-aided score (56%), supporting the presence of binaural interference. Se reporta el estudio de caso
de un niño (KB) quién demostró un interferencia binaural. KB utilizó amplificación unilateral desde la edad de 1.6 a los 4.6 años, donde sus puntajes de reconocimiento de palabras bajo auriculares eran marcadamente asimétricos, reflejando un
desempeño significativamente mejor en el oído amplificado que en el no amplificado, a pesar de una sensibilidad tonal sin amplificación similar para los dos oídos. Bajo la sospecha de que la asimetría en el reconocimiento de palabras se debiera a un deprivación
auditiva, se prescribió una amplificación binaural a la edad de 4.6 años. Tres meses después, se reportaron cambios adversos en la conducta del niño. A los 5.3 años, se notó una significativa asimetría interauricular en los puntajes de
reconocimiento de palabras con auriculares, en reconocimiento de palabras con amplificación unilateral (90% vs. 36%), y el puntaje bilateral con amplificación (56%), apoyando la presencia de una interferencia binaural.