bluuebunny/crossref_metadata_2025 huggingface dataset:
Psychological and Pedagogical Characteristics of a Teacher in the Process of Physical Education of Students
Authors: Griban Grygoriy , Asauliuk Inna , Yahupov Vasyl , Svystun Valentyna , Shukatka Oksana , Vasylieva Svitlana , Oleniev Dmytro , Yefimenko Pavlo , Agarkova Nataliia , Otroshko Olena
Published: March 2023

The effectiveness of the process of the physical education of students largely depends on the teacher of physical education, one’s competence, pedagogical skills, personal qualities, managerial capacity, and so on. The article is devoted to the study of psychological and pedagogical characteristics of a teacher in the process of physical education of students. The study was conducted in 2012-2022. 1323 students (528 males and 795 females) took part in the research. A survey of students was used to study their assessment of physical education teachers. The study of the relationship between students and teachers in the process of physical education showed that the relationship of respect is prevailing – 72.5 %, the relationship of familiarity is quite common – 13.6 %, despondency accounts for 10.4 %, there are also cases of advances (3.0 %) and flattery – 0.5%. It was found that 59.6 % of students prefer friendly relations with the teacher when the teacher is in the role of senior, a smaller proportion of students (30.9 %) prefer friendly relations and only 7.5 % prefer formal and 2.0 % – strict and inaccessible in physical and health-improving classes. The effectiveness of the impact on students depends largely on the authority of the teacher, one’s characterological, personal qualities, and managerial capacity, among which the most important are professionalism, pedagogical skill, experience, outlook, honesty, justice, patience, appearance, endurance.
Factors Favorable for the Learned Optimism in Preadolescence
Authors: Gazzi Dumitrina , Pitiruț Bianca , Hendreș Daniela Muntele
Published: March 2023

Prior research suggested that the learned optimistic explanatory style is positively associated with greater satisfaction in interpersonal relationships, a more effective approach of life stressors, better physical health and work productivity, less vulnerability to depression and also higher academic and athletic performances. Our research deals with how are learned optimism and learned pessimism predicted by academic, social and emotional self-efficacy, perceived autonomy-based parenting style, perceived control-based parenting style and proactive coping. Participants were 760 students (467 girls) - 12-year-old (20.5%), 13-year-old (31.8%) and 14-year-old (47.6%) – who voluntarily participated. They answered the questionnaires with which the research variables were operationalized. The present study contributes with its large number of participants to an overview of the factors that predict learned optimism and learned pessimism. Results indicated the importance of social self-efficacy, proactive coping and perceived control-based parental support in predicting learned optimism. Also, this paper shows that high learned pessimism coincides with high levels of difficult family situation (e.g. single-parent family) and reduced strength of social self-efficacy and academic self-efficacy, proactive coping and perceived control-based parental support. Important implications of this empirical research should be considered by social emotional learning programs for students, parents and teachers.
Prediction of Coronary Heart Disease on Civil Servants in Jember by Framingham Risk Score
Authors: Akbar Muhammad Nadzir A. , Suryono Suryono , Prasetyo Aris , Dewi Ricky Roosdiana
Published: March 2023

Coronary heart disease is one of the biggest causes of death in developing countries. Civil servants (PNS) are a group of people who are susceptible to the disease because of their busy lives. Framingham risk score (FRS) can predict the occurrence of coronary heart disease in the next 10 years. The purpose of this study was to determine the prediction of coronary heart disease for the next 10 years in civil servants in Jember Regency. This type of research is descriptive observational with a cross sectional design. The data was taken from the medical records of patients with echelon II and III civil servants who did a medical sheck up at Dr. Soebandi Hospital in December 2013. Prediction of coronary heart disease for the next 10 years using the FRS method. From 63 medical record data, the prediction results of coronary heart disease in civil servants were 76.2% low risk, 17.5% moderate risk, and 6.3% high risk.

Keywords: coronary heart disease, civil servants, framingham risk score
Valuing Mundane Manifestations of Rare, but Underdiagnosed, Diseases in Portugal: The Example of McArdle Disease
Authors: Mateus-Pinheiro António , Costa Tiago , Esperto Hélder , Moreira Sónia
Published: March 2023

N/a.
Revision Hip Arthroplasty in a Jehovah's Witness with Pelvic Discontinuity
Authors: Kusek Andrew , Hart Adam , Baldini Gabriele
Published: March 2023

Case:

A 68-year-old Jehovah's Witness (JW) presented with pelvic discontinuity 9 years after right total hip arthroplasty. Her pelvis was previously irradiated for cervical cancer. Meticulous hemostasis, blood conserving strategies, and a prophylactic arterial balloon catheter were used to mitigate bleeding. She underwent an uneventful revision total hip arthroplasty with excellent functional recovery and radiographic evaluation at 1 year postoperatively.

Conclusion:

Pelvic discontinuity in a JW with irradiated bone makes for a challenging revision arthroplasty with high bleeding risk. Preoperative coordination with anesthesia and blood loss mitigation strategies can lead to successful surgical outcomes in cases of high-risk surgery among JW patients.
An Efficient Gateway Node Selection Method for Clustering in Heterogeneous Mobile Ad-hoc Networks
Authors: Panse Trishna , Panse Prashant
Published: March 2023

Node heterogeneity such as different transmission range, battery backup and mobility leads to several issues for the network. To concentrate on these issues, we need some alternatives which are able to adapt to different characteristics and make decisions for smooth functioning. In a few years, numerous efforts have been dedicated to clustering methods for wireless mobile ad-hoc networks in order to results efficient and correct routing procedures. In the context of clustering devices of a cluster nominated as cluster member, cluster head and cluster gateway on the basis of different roles. Clustering leads to cluster-head and gateway selection overhead that requires focusing by researchers. The motive of the work is to study and analyze effects of heterogeneity properties. With this, an efficient gateway selection method is also proposed. The result of the proposed method is evaluated by considering several network performance parameters such as routing overhead, throughput, network lifetime.
Prolonged efficacy of Bifidobacterium lactis in the treatment of functional dyspepsia
Authors: Zhang Qi , Li Guang , Zhao Wen , Zhou Limian , Zhang Xiaoxu , He Jingjing , An Peng , Liu Yinghua , Zhang Chengying , Zhang Yong , Liu Simin , Liu Wei-Hsien , Liu Fudong , Li Yixuan , Jiang WenJian , Wang Xifan , Wang Xiaoyu , Wang Qingyu , Fang Bing , Guo Meng , Zhao Yuyang , Ren Yimei , Niu Xiaokang , Li Dongjie , Zhang Chao , Shi Shaoqi , Wang Ran , Liu Xinjuan , Hung Wei-Lian , Ren Fazheng
Published: March 2023

Background

Current treatment for functional dyspepsia (FD) has limited and unsustainable efficacy. Probiotics have the potential to alleviate FD; However, the underlying mechanism remains unclear. This study aimed to evaluate the effect and mechanism of probiotics in alleviating FD.

Methods

A randomized, positive-drug and placebo-controlled clinical trial was conducted; 200 FD patients were randomly divided into four groups (placebo, positive control [proton pump inhibitors, PPI] or Bifidobacterium lactis BL-99 [low, high doses]). The clinical response rates in 8-week treatment, 2-week follow-up and 6-week questionnaire survey periods were recorded. Faecal microbiota and metabolites were assessed by metagenomics, un-target and target metabolomics technology.

Results

The clinical response rate for BL-99_high [43 (95.6%) of 45] group was significantly higher than that for placebo [28 (62.2%) of 45, P = 0.001], BL-99_low [36 (76.6%) of 47, P = 0.019] or positive control group [34 (70.8%) of 48, P = 0.006] after an 8-week treatment. In particular, BL-99_high group was still higher than that for placebo or positive control group after 2-week follow-up and 6-week questionnaire survey periods. Further metagenomic and metabolomics studies found that PPI significantly decreased the gut microbiota diversity, induced the cluster of Escherichia enterotype and decreased butyrate contents. Interestingly, BL-99 converted the gut microbiota enterotype from Bacteroidetes (Alistipes finegoldii, Alistipes shahii) to Firmicutesc (Roseburia intestinalis, Roseburia inulinivorans) and Escherichia enterotype was not clustered after 8-week treatment, which activates carbohydrate esterase activity, and increases faecal and serum butyrate levels.

Conclusion

BL-99 sustainably alleviated FD symptoms by altering the taxonomic composition and functional potential of the FD microbiome.
Trial registration Chictr.org.cn ChiCTR2000041430.
Rainfall and Moisture Adequacy Index (MAI) based crop planning in Lower Brahmaputra Valley Zone (LBVZ) of Assam
Authors: Lagna Lagnajeet Roy , Khanikar Punya Gogoi Khanikar Punya Gogoi , Sarmah Kushal Sarmah Kushal
Published: March 2023

Rainfall and irrigation water both are actively useful, but farmers rely more on precipitation and soil water holding capacity than providing irrigation. In climatological view rainfall analysis with measurement of SD and CV [Chowdhury et. al., (2019)] and in meteorological point of view the amount of actual evapotranspiration is directly proportional to the yield of biomass [Anderson et al., (2011)] that’s why Moisture Adequacy Index (MAI) is one of the important Index used in crop water balance aspect. The present study had been undertaken with the objectives to analysis of rainfall and estimation of Moisture Adequacy Index (MAI) for the districts of Lower Brahmaputra Valley Zone (LBVZ) of Assam using the raw datasets of rainfall and temperature for a period of 32 years (1990-2021). From the rainfall analysis and MAI of LBVZ we conclude the preferred cropping pattern for the farmers. In this research we find that geological pattern is directly affecting the rainfall pattern and thus agriculture pattern need to improvise in this era to cope up with climate change. The GIS choropleth map of the average annual rainfall and MAI for different districts of LBVZ were also drawn to have an idea about spatial rainfall distribution of the Zone.
Laboratory standardization of loop-mediated isothermal amplification (LAMP) assay for Limnoperna fortunei (Dunker 1857) detection
Authors: de Paula Rayan Silva , Monte-Neto Rubens Lima , Wallau Gabriel da Luz , Reis Mariana de Paula , Souza Clara Carvalho , Nogueira Júlia Meireles , Cardoso Antonio Valadão , Jorge Erika Cristina
Published: March 2023

Among invasive species known to occur in South America, the bivalve mollusc Limnoperna fortunei, which the presence is linked to several environmental and economic problems. Early detection and mitigation actions are needed to limit its impact in the remaining L. fortunei-free areas. PCR-based molecular methods have become the gold standard methodology for L. fortunei detection. However, PCR-based methods require complex logistics from field sampling to laboratory processing. Thus, the use of methods that can be directly applied in the field can speed up the detection process. This work aimed to establish, for the first time, the loop-mediated isothermal amplification (LAMP) method for the detection of L. fortunei, with perspectives for in situ application. A set of primers designed for LAMP was tested for amplification of DNA from L. fortunei adult tissues and environmental samples containing bivalve larvae. The test showed a limit of detection as low as 0.01 ng of DNA obtained from adult tissue samples and a minimum reaction time of 60 min. The set of primers used seems to be specific for L. fortunei, since there was no cross-amplification with other bivalve or invasive molluscs that co-occur with the golden mussel in the same environment. The LAMP technique also proved to be efficient in amplifying DNA derived from L. fortunei larvae, demonstrating it to be a robust method regarding potential environmental reaction inhibitors. Although the results obtained here were acquired under controlled laboratory conditions, the LAMP method is a promising tool to integrate L. fortunei invasion monitoring protocols.
Impact of Sleep Disruptions on the Mental Health of Atrial Fibrillation Inpatients: A Cross-sectional Study
Authors: Hu Lixing , Ding Xiaotong , Tang Min
Published: March 2023

Objectives: To evaluate theinteractions between anxiety, depression and sleep attributes in atrial fibrillation inpatients of a single tertiary center in China to improve identification of patients who require additional psychological care.
Methods: We retrospectively enrolled 332 atrial fibrillation inpatients and evaluated their psychological and sleep status with the Zung Self-Rating Anxiety Scale (SAS), Zung Self-Rating Depression Scale (SDS), and Pittsburgh Sleep Quality Index (PSQI), respectively. Potential risk factors for anxiety and depression were analyzed by multivariate logistic regression. Odds ratios (OR) for risk of poor sleep quality were adjusted by age and gender in patients with different psychological statuses (anxiety only, depression only, combined anxiety and depression).
Results: Participants with an average age of 58.6±10.5years, and 67.8% males were involved in the study. Patients with anxiety and depression accounted for 21.1 and 34.0%, respectively. Potential risk factors for anxiety were female (P = 0.045) and poor sleep quality (P = 0.001); for depression were obesity (P = 0.033) and poor sleep quality (P<0.001). The likelihood of experiencing sleep disturbances was 3.69 times greater in patients suffering from both anxiety and depression (OR: 3.69; 95% confidence interval [CI]: 1.94–7.01; P＜0.001), 2.14 times greater in depressed patients (OR: 2.14; 95% CI: 1.16–3.96; P = 0.016), and 2.06 times greater in anxious patients (OR=2.06; 95%CI: 0.72-5.94; P = 0.180).
Conclusions: Psychological disturbances are prevalent among Chinese inpatients with atrial fibrillation, especially among females and obese individuals. There is an association between anxiety and depression respectively, with sleep disorders. Persistent sleep disruption may be a significant risk factor for psychological disorders, and patients suffering from anxiety and depression have the highest risk for sleep disruption.
A process model of learning effect and learner emotion occurrence in offline learning environments—an empirical study for the learning spiral model
Authors: Mou Xiangwei , Xin Yu , Song Yongfu , Xiang Jinshan , Tang Yuanbin
Published: March 2023

The application of non-cognitive factors represented by facial emotion in educational evaluation has attracted much attention in recent years. There are many existing studies on facial emotion assisted education evaluation, but most of them are based on virtual learning environments, which means that the research on facial emotion and learning effect in offline learning environments is sparse. In order to solve this problem, this study designed an emotion observation experiment based on the offline learning environment, obtained the type of learner facial emotion and learning effect of 127 college students, and further explored the relationship between the two. The results show that: 1) We obtained eight types of learner emotion through the combined description method: joy, relaxation, surprise, meekness, contempt, disgust, sadness, anxiety and their respective PAD emotional mean. 2) We obtained the correlation results of the six emotions of joy, relaxation, surprise, meekness, contempt, and anxiety with the learning effect and the predicted value of the learning effect. 3) We then constructed an explanatory model of learner emotion and learning effect based on the offline learning environment.
Noise Resistance of Next Generation Reservoir Computing: A Comparative Study with High-Order Correlation Computation
Authors: Liu Shengyu , Xiao Jinghua , Yan Zixiang , Gao Jian
Published: March 2023

Reservoir computing (RC) methods have received more and more attention and applications in chaotic time series prediction with their simple structure and training method. Recently, the next generation reservoir computing (NG-RC) method (Nature Communications,12,5564) has been proposed with less training cost and better time-series predictions. Nevertheless, in practice, available data on dynamic systems are contaminated with noise. Though NG-RC is shown highly efficient in learning and predicting, its noise resistance captivity is not clear yet, limiting its use in practical problems. In this paper, we study the noise resistance of the NG-RC method, taking the well-known denoising method, the high-order correlation computation (HOCC) method, as a reference. Both methods have similar procedures in respect of function bases and regression processes. With the simple ridge regression method, the NG-RC method has a strong noise resistance for white noise, even better than the HOCC method. Besides, the NG-RC method also shows a good prediction ability for small color noise, while it does not provide correct reconstruct dynamics. In this paper, other than reconstruction parameters, four numerical indicators are used to check the noise resistance comprehensively, such as the training error, prediction error, prediction time, and auto-correlation prediction error, for both the short-time series and long climate predictions. Our results provide a systematic estimation of NG-RC's noise resistance capacity, which is helpful for its applications in practical problems.
Assessment of Quality of Life and Socioeconomic Inequality in Children with Cyanotic Congenital Heart Disease in Sulaimaniyah, Iraq
Authors: Kamal Niaz Mustafa , Salih Aso Faiq , Ali Bushra Mohammed
Published: March 2023

Background: The concept of quality of life (QoL) covers physical/psychological health, level of independence, social relations, environmental factors, and individual beliefs.
Objective: This study aimed to investigate health-related QoL in children with cyanotic congenital heart disease (CCHD) and to determine socioeconomic inequality in CCHD.
Patients and Methods: This case-control study was conducted at Children’s Heart Hospital and Primary Healthcare Centers on 400 children (200 healthy and 200 with CCHD) from December 01, 2021, to May 01, 2022, in Sulaimaniyah, Iraq. For this purpose, a 5 Likert Scale QoL questionnaire was used to collect the data of patients and their parents through a direct face-to-face interview. Then, children's sociodemographic data and parents' socioeconomic status (SES) was investigated together with another 22 items in 6 domains.
Results: Studied children had equal gender and age distribution. CCHD was more prevalent in families with low SES, and ECI was - 0.44. Children with CCHD had significantly lower mean scores for the overall QoL dimension (Mean rank=124) compared to healthy children (Mean rank=277) (P≤0.001). About 91.5% of CCHD patients had poor QoL compared to 7.5% of healthy children. The mean SpO2 levels of healthy children were 9 % higher than CCHD children (P<0.001). Moreover, parents with CCHD children stated that 57% of their children had moderate to excellent health, while those with healthy children reported 98% (P=0.001).
Conclusions: Significant deficits in all QoL dimensions were found in CCHD children. Also, we discovered an inequality distribution of CCHD in families with lower SES.
Stronger diversification of human thermal stress conditions observed in low-income Asian countries
Authors: Yan Yechao , Xu Yangyang , Yue Shuping
Published: March 2023

The day-to-day diversity of thermal conditions determines the range of human thermal sensation within a year, and its long-term shift affects thermal comfort demand with profound economic and public health implications. While previous studies have documented historical trends in specific thermal stress events regionally, such as heat waves and cold spells, how the temporal diversity of various thermal stress types has changed in response to climate change remains unexplored. Here, we present a practical and easy-to-use classification framework to characterize daily thermal conditions and then we use the Shannon’s index to quantify the diversity and its long-term shift over the past three decades (1990–2019). Using a high-spatial-resolution dataset of Universal Thermal Climate Index (UTCI) we developed for Asian regions, we quantify the diversity of daily thermal stress types and the population-weighted trends for each country in South, Southeast and East Asia. We find that human thermal stress conditions have become more diversified, especially in low-income tropical countries. This disproportionately stronger diversification in daily thermal stress types may worsen socio-economic inequity between wealthy and poor countries, posing great adaptation challenge for the latter.
Genetic diversity and albumin content of striped snakehead Channa striata in Indonesia; a study on farmed and wild fish from five main islands
Authors: Hidayati Rohana , Purwanto - , Rustadi - , Hardaningsih Ignatius , Murwantoko - , Sari Dini Wahyu Kartika
Published: March 2023

Genetic characterization and eminent traits of species are crucial in determining the direction of aquaculture development. The genetic diversity of striped snakehead (Channa striata) across five main islands in Indonesia from aquaculture and wild was explored through its partial mtDNA COI. Subsequently, this study examined the albumin content extracted from the meat and comprehensively aligned it with the variation of its genotype. Phylogeny studies showed the Sumatran snakehead fish sample forms its own cluster and has a long genetic distance from other samples. Interestingly, its albumin content in Sumatra samples was significantly higher (1.907%) than others (1.253-1.509%). Further analysis of albumin content from the Borneo samples from the same taxa in the phylogeny tree, showed no significant difference between farmed and wild C. striata. The findings of this study are fundamental for initiating a selective breeding program and developing conservation management.
Transcriptomic and Metabolomic Analysis of Anthocyanin and Carotenoid Biosynthesis in Red and Yellow Fruits of Sweet Cherry (Prunus avium L.) during Ripening
Authors: Wang Qinghao , Jing Luyang , Xu Yue , Zheng Weiwei , Zhang Wangshu
Published: March 2023

Diversity of fruit color in sweet cherry (Prunus avium L.) has been attributed to the presence of either anthocyanin or carotenoid. We profiled the anthocyanin and carotenoid metabolites to investigate the most different pigments and the underlying regulatory mechanisms of differential expression genes (DEGs) between red and yellow fruits of sweet cherry.
Profiled the two cultivars,‘Jiangnanhong’(JNH, red fruits) and‘Chaoyang’(CY, yellow fruits) anthocyanin and carotenoid metabolites by LC-MS/MS and transcriptome analysis by RNA-seq to test the difference of gene expression and metabolic substances between the two varieties.
Cyanidin-3-O-rutinoside was the most different pigment between two cultivars, the content of which in red fruit was significantly higher than yellow one during the whole ripening stage (stage 3 and stage 4). Total carotenoid content in the two color types of fruits were close, but the content in yellow fruit showed more stable after harvest. Based on the transcriptome data, the heatmap of selected structural DEGs showed that all of the anthocyanin genes expressed significantly higher levels in red fruits than that in yellow fruits. Two unigenes encoding chalcone synthase (CHS) and UDP glucose-flavonoid 3-O-glucosyltransferase (UFGT) expressed 1134.58 and 1151.24 times higher in red than in yellow fruits at stage 4, respectively.
Correlation analysis showed that anthocyanin genes in JNH were negatively correlated with that in CY, contrastly, there were some strong correlations were observed between two cultivars in carotenoid genes. Thus, the coloration of sweet cherry was mainly attributed to anthocyanin-related genes.
Androgen receptor signalling transactivator lncRNAs PRNCR1 and PCGEM contribute to PCOS pathogenesis
Authors: Nabi Mudasar , Rasool Shayaq Ul Abeer , Ashraf Sairish , Andrabi Syed Mudasir , Amin Shajrul
Published: March 2023

polycystic ovary syndrome is the most common endocrine, reproductive disorder of women in their reproductive years. It is commonly considered as an androgenic disorder. Apart from high circulating testosterone levels, hyperandrogenism can also be attributed to the hyperactive androgen receptor (AR). Androgen receptor mediated signalling involves the association of multiple coactivators and corepressors and any aberrant activity of these factors may disrupt the normal transcriptional activity of AR and hence may act as contributing factors in the pathophysiology of various diseases. LncRNAs prostate cancer associated non-coding RNA 1 (PRNCR1) and prostate cancer gene expression marker 1 (PCGEM1) act as androgen receptor coactivator lncRNAs. The study was aimed at determining the association of lncRNAs PRNCR1 and PCGEM1 with PCOS. In this case-control study, a total of 178 participants were recruited these included 105 PCOS cases and 73 age-matched healthy controls. The Anthropometric, Metabolic and hormonal characteristics of the participants were determined. Total RNA was isolated from peripheral mononuclear blood cells and reverse transcribed into cDNA. Quantitative real-time PCR (qPCR) was done to study the expression pattern on lncRNAs. The association between different hormonal and metabolic parameters with the expression of PRNCR1 and PCGEM1 was determined by correlation analysis. Our study for the first time demonstrated that lncRNA PRNCR1 and PCGEM1 are overexpressed in Kashmiri women with PCOS. The expression levels of PRNCR1 (PRNCR1, 5.26 ± 1.77 versus 1.22 ± 0.73; P < 0.001) and PCGEM1 (PCGEM1, 3.39 ± 1.88 versus 1.23 ± 0.74; P < 0.001) were significantly higher in PCOS women compared to controls. Furthermore, lncRNA PRNCR1 showed a positive correlation with testosterone (P < 0.001).
Video Action Recognition Collaborative Learning with Dynamics via PSO-ConvNet Transformer
Authors: Nguyen Huu Phong , Ribeiro Bernardete
Published: March 2023

Recognizing human actions in video sequences, known as Human Action Recognition (HAR), is a challenging task in pattern recognition. While Convolutional Neural Networks (ConvNets) have shown remarkable success in image recognition, they are not always directly applicable to HAR, as temporal features are critical for accurate classification. In this paper, we propose a novel dynamic PSO-ConvNet model for learning actions in videos, building on our recent work in image recognition. Our approach leverages a framework where the weight vector of each neural network represents the position of a particle in phase space, and particles share their current weight vectors and gradient estimates of the Loss function. To extend our approach to video, we integrate ConvNets with state-of-the-art temporal methods such as Transformer and Recurrent Neural Networks. Our experimental results on the UCF-101 dataset demonstrate substantial improvements of up to 9% in accuracy, which confirms the effectiveness of our proposed method. Overall, our dynamic PSO-ConvNet model provides a promising direction for improving HAR by better capturing the spatio-temporal dynamics of human actions in videos. The code is available at https://github.com/leonlha/Video-Action-Recognition-Collaborative-Learning-with-Dynamics-via-PSO-ConvNet-Transformer.
Study on acoustic emission characteristics and damage evolution of shale under uniaxial compression
Authors: Wu Wenjie , Chan CheeMing , Gu Yilei , Su Xiaopeng
Published: March 2023

Acoustic emission tests under uniaxial compression of shale were carried out by using MTS815 rock servo test system and PCI-2 acoustic emission system. The law of acoustic emission and its damage evolution characteristics are analyzed and a uniaxial compression damage constitutive model of shale based on acoustic emission characteristics is established. The research shows that: (1) The uniaxial compression process of shale can be divided into four stages: crack compaction stage - elastic stage to the stable development stage of micro-elastic fracture - unstable fracture development stage - post-rupture stage. The acoustic emission signals are less during crack compaction stage and elastic stage to the stable development stage of micro-elastic fracture. When the axial stress reaches the damage strength σcd, which is about 80% of the peak strength, a large number of acoustic emission signals begin to be generated. There will be a large number of acoustic emission phenomena in the unstable fracture development stage and post-fracture stage. (2) The acoustic emission signal can well reflect the internal damage and destruction process of shale. The damage factor D shows a trend of decreasing first and then increasing with the increase of acoustic emission cumulative ringing counts, rather than monotonically increasing. When the acoustic emission cumulative ringing counts and damage factor start to increase slowly, the corresponding stress can be regarded as the crack initiation strength σci. (3) The damage factor D is proportional to the cumulative acoustic emission ringing counts N. According to the acoustic emission characteristics of rock specimens at different stages, the relationship between the damage factor D and the acoustic emission cumulative ringing counts C at different stages is obtained by linear fitting using origin software, thus a more reasonable shale damage constitutive model is established. In this way, the theoretical stress-strain curve obtained by the damage constitutive model is more consistent with the actual stress-strain curve.
3’ end hydrolysis activity of the Bst polymerase enables rapid and sensitive identification of SARS-CoV-2 variants
Authors: Ooi Kean Hean , Liu Mengying Mandy , Burhanudin Muhammad Safwan Bin , Thirunavukarasu Surenthar , Oh Zhi Qi Victor , Kwa Shiuan Ning Shannon , Ng Tian Hui Valerie , Nimsamer Pattaraporn , Payungporn Sunchai , Kaewsapsak Pornchai , Tan Meng How
Published: March 2023

Sensitive and accurate detection of genetic variants is important in many clinical applications, including the identification of specific pathogens or viral subtypes. However, existing methods are too time-consuming or complex, hampering their deployment in point-of-care settings. Here, we demonstrate that the intrinsic 3’ hydrolysis activity of the Bst polymerase deployed in loop-mediated isothermal amplification (LAMP) reactions can cleave off an end-conjugated quencher from a fully hybridised DNA oligonucleotide, allowing us to develop a fluorescent probe-based method that is highly sensitive to single nucleotide mismatches. We utilize our method, named SNiPER, to build diagnostic assays that detect different SARS-CoV-2 variants, including Alpha, Beta, Delta, and Omicron. Furthermore, we manufacture a simple device with 3D printing and inexpensive off-the-shelf electronics components to enable point-of-care testing and validate our assays on 32 patient samples, achieving perfect concordance with sequencing-based variant classification. Our technology can be quickly reconfigured to detect different pathogens and their variants, providing us with a useful tool to address any future infectious disease outbreak.
Impact of macrolide treatment on long-term mortality in patients admitted to the ICU due to CAP: A targeted maximum likelihood estimation and survival analysis
Authors: Reyes Luis Felipe , Garcia Esteban , Ibáñez-Prada Elsa D. , Serrano-Mayorga Cristian C. , Fuentes Yuli V. , Rodriguez Alejandro , Moreno Gerard , Bastidas Alirio , Gómez Josep , Gonzalez Angélica , Frei Christopher R , Celi Leo A. , Martin-Loeches Ignacio , Waterer Grant
Published: March 2023

Introduction:
Patients with community-acquired pneumonia (CAP) admitted to the intensive care unit (ICU) have high mortality rates during the acute infection and up to ten years thereafter. Recommendations from international CAP guidelines include macrolide-based treatment. However, there is no data on the long-term outcomes of this recommendation. Therefore, we aimed to determine the impact of macrolide-based therapy on long-term mortality in this population.
Methods
Registered patients in the MIMIC-IV database 16 years or older and admitted to the ICU due to CAP were included. Multivariate analysis, targeted maximum likelihood estimation (TMLE) to simulate a randomised controlled trial, and survival analyses were conducted to test the effect of macrolide-based treatment on mortality six-month [6m] and twelve-month [12m] after hospital admission. A sensitivity analysis was performed excluding patients with Pseudomonas aeruginosa or MRSA pneumonia to control for Healthcare-Associated Pneumonia (HCAP).
Results
3775 patients were included, and 1154 were treated with a macrolide-based treatment. The non-macrolide-based group had worse long-term clinical outcomes, represented by 6m (31.5 [363/1154] vs 39.5 [1035/2621], p < 0.001) and 12m mortality (39.0 [450/1154] vs 45.7 [1198/2621], p < 0.001). The main risk factors associated with long-term mortality were Charlson comorbidity index, SAPS II, septic shock, and respiratory failure. Macrolide-based treatment reduced the risk of dying at 6m (HR [95% CI] 0.69 [0.60, 0.78], p < 0.001) and 12m (0.72 [0.64, 0.81], p < 0.001]). After TMLE, the protective effect continued with an additive effect estimate of -0.069.
Conclusion
Macrolide-based treatment reduced the hazard risk of long-term mortality by almost one-third. This effect remains after simulating an RCT with TMLE and the sensitivity analysis for the HCAP classification.
Surgical management of unstable large displacement upper femoral epiphysiolysis
Authors: Coulibaly Kalifa , Sanogo Cheick Oumar , Diallo Mahamadou , Moussa Abdoul Kadri , Traore Soumana , Diallo Aboubacar , Traoré Ousmane , Tambassi Sory Ibrahim , Toure Layes
Published: March 2023

Introduction: Superior femoral epiphysiolysis (SFE) is a slippage of the femoral head relative to the cervical growth plate. Unstable forms with large displacement have a high risk of femoral head necrosis and chondrolysis. Rapid reduction of epiphyseal displacement has been blamed for epiphyseal ischemia.
Objective: We present here the anatomical results of a technique of progressive reduction of epiphyseal displacement by transtibial traction followed by percutaneous fixation of the femoral head with screws and/or pins.
Patients and Methods: This was a retrospective descriptive study over a 10-year period from January 01, 2013 to December 31, 2022. It focused on the surgical treatment of unstable upper femoral epiphysiolysis with large displacement at the orthopedic trauma department of the Kati University Hospital. Continuous progressive traction on the Boppe splint through a pin under the anterior tibial tuberosity was performed for 15 days in all patients. The hip and knee were flexed to 90°. Fixation was performed with either one screw, two screws, or one screw and a pin. No contralateral preventive fixation was performed.
Results: At final follow-up, all nine patients were asymptomatic. Radiologically, all nine patients had a femoral head free of epiphyseal necrosis. In eight patients, the posterior tilt was absent, identical to that obtained after the traction period (Figure 3). Only one patient had a moderate posterior tilt with a neck overhang of less than 25%. Functionally, the PMA score was very good in 8 cases and good in one case.
Conclusion: This study shows that the treatment of acute and unstable forms of upper femoral epiphysiolysis by progressive reduction with transtibial traction is an effective technique. It allows a satisfactory reduction of the displacement, an easy fixation of the slip with a lower risk of necrosis of the femoral head and of chondrolysis.
WITHDRAWN: Understanding the drivers of the live bird trade in Brazil
Authors: Azeredo Luane Maria Melo , Alves Rômulo Romeu da Nóbrega
Published: March 2023

BACKGROUND
Several bird species involved in commercial trade of pets in Brazil, have presented occurrences outside their natural habitat, which may indicate possible introductions due to this activity. In this context we sought to evaluate the factors that influence the public’s interest in wild birds sold as pets in Brazil, and the relationship of those factors with new occurrences of birds outside their natural distribution area, discussing the relationship of commercial trade with possible introductions in new environments.
METHODS
We compiled the richness of bird species traded in Brazil and obtained comparative data of public interest directed to these species through the Google Trend tool. In addition, we gathered data on biological attributes and data on the sale price of the species in the trade, to analyze which factors would be related to public interest. New occurrences of birds outside their natural range were considered only if they were at a minimum distance of 800 km. Thus, factors related to public interest were then used to assess whether there was a relationship with these new occurrences. Data analysis was performed using Mixed Generalized Linear Models (GLMMs).
RESULTS
The results indicated that the public’s interest in certain species varies according to the region of the country, suggesting that the profile of interest in wild birds by people on the internet can be guided by sociocultural factors of each location. In addition, we found that the public interest is greater for songbirds, with generalist diet, which live in more open environments, have a greater distribution area and are sold at lower prices. All those factors, except for the distribution area, also showed to be related to the birds that presented new occurrences.
CONCLUSIONS
The public's preference for birds from more open and more generalist environments is probably the most important data, as such factors generally indicate greater environmental tolerance, which may favor the establishment of these birds in new environments. Thus, actions aimed at the conservation of commercialized species are essential to reduce the interregional trade of species, and consequently reduce the impact on natural populations and reduce the potential for new biological introductions.
Outcome context-dependence is not WEIRD:
Comparing reinforcement- and description-based economic preferences worldwide
Authors: Anllo Hernan , Bavard Sophie , Benmarrakchi FatimaEzzahra , Bonagura Darla , Cerrotti Fabien , Cicue Mirona , Gueguen Maëlle , Guzmán Eugenio , Kadieva Dzerassa , Kobayashi Maiko , Lukumon Gafari , Sartorio Marco , Yang Jiong , Zinchenko Oksana , Bahrami Bahador , Silva Jaime , Hertz Uri , Konova Anna , Li Jian , O'Madagain Cathal , Navajas Joaquin , Reyes Gabriel , Sarabi-Jamab Atiye , Shestakova Anna , Sukumaran Bhasi , Watanabe Katsumi , Palminteri Stefano
Published: March 2023

Recent evidence indicates that reward value encoding in humans is highly context-dependent, leading to suboptimal decisions in some cases. But whether this computational constraint on valuation is a shared feature of human cognition remains unknown. To address this question, we studied the behavior of individuals from across 11 countries of markedly different socioeconomic and cultural makeup using an experimental approach that reliably captures context effects in reinforcement learning. Our findings show that all samples presented evidence of similar sensitivity to context. Crucially, suboptimal decisions generated by context manipulation were not explained by risk aversion, as estimated through a separate description-based choice task (i.e., lotteries) consisting of matched decision offers. Conversely, risk aversion significantly differed across countries. Overall, our findings suggest that context-dependent reward value encoding is a hardcoded feature of human cognition, while description-based decision-making is significantly sensitive to cultural factors.
The Partial Wave Sub-Amplitude Fourier Transform with Born Probability Interpretation in Crystallography
Authors: Bhanumoorthy P.
Published: March 2023

We identify Maxwell-Schrödinger equation as the governing partial differential equation. We name the solution as unitcell function such that Born probability rule interprets electron density as modulus square of the unitcell function. The existing traditional full-amplitude Fourier transform relation with electron density as directly the inverse Fourier transform of structure factors therefore violates Born probability rule. We derive the partial wave Parse-val relation as the probability conservation law using Rayleigh expansion. We subdivide the experimental full-amplitudes into partial wave sub-amplitudes, which become amplitudes of spherical waves. The subscript on a sub-amplitude represents localization within the unit-cell and therefore spherical waves become localized wave packets. As a probability measure, the amplitude of a localized wave packet is exact and merits over the amplitude of a non-localized plane wave. We measure angle dependence as the precision angles data. We derive the partial wave sub-amplitude Fourier transform relation to determine orbital structures of individual atoms using the precision angles data. The partial wave sub-amplitude Fourier transform relation alone obeys Born probability rule and hence becomes the only acceptable Fourier transform relation in quantum crystallography.
Nonlinear electrostatic structures and stopbands in a three-component magnetosheath plasma
Authors: Rufai Odutayo , Singh S. V , Lakhina G. S
Published: March 2023

Large amplitude parallel propagating electric field structures of nonlinear electron-acoustic waves are examined in an unmagnetized magnetosheath plasma. Based on the observations and simulations by Ergun et al. 2016, the plasma in the magnetosheath side of the ion diffusion layer is modeled by a 3-component adiabatic fluid dynamic plasma consisting of cold magnetospheric (MSP) electrons, magnetosheath electrons, and background ions. The plasma model is composed of magnetosheath plasma components such as fluid dynamic system of a cold electron beam, warm electrons, and background ions. Using the Sagdeev pseudopotential technique, for the plasma parameters recorded by the Magnetospheric Multiscale (MMS) mission in the magnetosheath side of the ion diffusion region, existence regime of the nonlinear electrostatic solitary wave structures is obtained with the possibilities of stopbands (forbidden gap region). Stopbands or the forbidden gap region exists even when the drift velocity of the cold electron beam is zero. The forbidden gap region becomes wider and the Mach numbers of the regions supporting solitary structures become larger by an increase in the drift velocity of the cold electron beam. The results are in agreement with the magnetosheath electrostatic waves having amplitudes of 100s mV/m and frequencies up to 3.2 kHz observed by the MMS.
A Hybrid Clustering Approach for link prediction in Heterogeneous Information Networks
Authors: Sajjadi Zahra Sadat , Esmaeili Mahdi , Ghobaei-Arani Mostafa , Minaei-Bidgoli Behrouz
Published: March 2023

In recent years, researchers from academic and industrial fields have become increasingly interested in social network data to extract meaningful information. This information is used in applications such as link prediction between people groups, community detection, protein module identification, etc. Therefore, the clustering technique has emerged as a solution to finding similarities between social network members. Recently, in most graph clustering solutions, the structural similarity of nodes is combined with their attribute similarity. The results of these solutions indicate that the graph's topological structure is more important. Since most social networks are sparse, these solutions often suffer from insufficient use of node features. This paper proposes a hybrid clustering approach for link prediction in heterogeneous information networks (HINs). In our approach, an adjacency vector is determined for each node until, in this vector, the weight of the direct edge or the weight of the shortest communication path among every pair of nodes is considered. A similarity metric is presented that calculates similarity using the direct edge weight between two nodes and the correlation between their adjacency vectors. Finally, we evaluated the effectiveness of our proposed method using DBLP and Political blogs datasets under entropy, density, purity, and execution time metrics. The simulation results demonstrate that while maintaining the cluster density significantly reduces the entropy and the execution time compared with the other methods.
The Sharp Bound of the Third Hankel Determinant of kth- Root Transformation for Functions Associated with Lemniscate of Bernoulli
Authors: Rath Biswajit , Karri Sanjay Kumar , D. Vamshee Krishna , G. K. Surya Viswanadh
Published: March 2023

The objective of this paper is to estimate the sharp bound of thethird Hankel determinant for kth- root transformation to the familiar subfamilyof starlike functions associated with the right half of lemniscate of Bernoulli.
2020 Mathematics Subject Classification. 30C45, 30C50.
ABC Classification System ： Establishment and Preliminary Evaluation of CT-based Classification for Distal Radius Fracture
Authors: Zhang Jun , Yao Xiaoke , Song Yanan , Yin Peng
Published: March 2023

Objective
Establish a new classification system of distal radius fracture based on computed tomographic (CT), and evaluate its reliability and reproducibility preliminarily, and provide a new theoretical reference for clinicians to use the clinical classification system.
Methods
The imaging data and clinical data of 204 inpatients with distal radius fractures during 6 years from January 1, 2014 to January 1, 2019 in orthopaedic department were analyzed retrospectively and classified based on CT. Three observers evaluated the image data of 48 randomly selected cases based on CT at different time nodes of T1 and T2. Cohen's kappa was used to calculate the consistency.
Results
Among 204 cases, there were 12 cases of type A, including 6 cases of type A1, 4 cases of type A2 and 2 cases of type A3. There were 6 cases of type B, including 2 cases of type B1, 2 cases of type B2 and 2 cases of type B3. There were 186 cases of type C, including 32 cases of type C1, 127 cases of type C2 and 27 cases of type C3. There was no significant difference in Disabilities of the Arm, Shoulder and Hand (DASH), Patient-Rated Wrist Evaluation(PRWE) and VAS scores among all types (P > 0.05). The results of interobserver reproducibility were kappa = 0.985, ICC = 0.984 in the first evaluation, kappa = 0.986, ICC = 0.986 in the second evaluation. The results of intraobserver reproducibility were O1 = 0.991, O2 = 0.991, O3 = 0.989 respectively.
Conclusions
The new classification system of distal radius fracture based on CT has theoretical and practical significance for incision selection, fracture reduction and internal fixation. ABC typing system is clear, comprehensive, easy to understand and remember. Moreover, it has higher interobserver reliability and intraobserver reproducibility than other systems reported at present.