bluuebunny/crossref_metadata_2025 huggingface dataset:
A Virtual Reality System for Improved Image-based Planning of Complex Cardiac Procedures
Authors: Deng Shujie , Wheeler Gavin , Toussaint Nicolas , Munroe Lindsay , Bhattacharya Suryava , Sajith Gina , Lin Ei , Singh Eeshar , Chu Ka Yee Kelly , Kabir Saleha , Pushparajah Kuberan , Simpson John M , Schnabel Julia A , Gomez Alberto
Published: August 2021

The intricate nature of congenital heart disease requires understanding of complex, patient-specific three-dimensional dynamic anatomy of the heart, from imaging data such as three-dimensional echocardiography for successful outcomes from surgical and interventional procedures. Conventional clinical systems use flat screens and therefore display remains two-dimensional, which undermines the full understanding of the three-dimensional dynamic data. Additionally, control of three-dimensional visualisation with two-dimensional tools is often difficult, so used only by imaging specialists. In this paper we describe a virtual reality system for immersive surgery planning using dynamic three-dimensional echocardiography, which enables fast prototyping for visualisation such as volume rendering, multi-planar reformatting, flow visualisation, and advanced interaction such as three-dimensional cropping, windowing, measurement, haptic feedback, automatic image orientation, and multi-user interactions. The available features were evaluated by imaging and non-imaging clinicians, showing that the virtual reality system can help improve understanding and communication of the three-dimensional echocardiography imaging and potentially benefit congenital heart disease treatment.
Some Results for a Time Interval Approach to Field Theory and Gravitation
Authors: Hollestelle Harmen Henricus
Published: August 2021

This paper consists of two parts. In part I some new relations for a field theory with time intervals are derived. One concept of field theory evaluated is complementarity, another is field operators both defined within a time interval description. Part II includes specific results and commentary. Discussed are time interval dependent wave propagation surfaces for star source emission waves and derived is a metric propagation surface area requirement. The results allow to consider one same field that like gravitation within General Relativity applies to both non zero and zero mass. The associated field energy is space time dependent for non zero mass, and is related to a space time dependent metric tensor for zero mass wave particles. Defined is internal energy transfer where wave particle numbers increase linearly and mass and momentum diminish, decrease inversely with the distance from the wave emission source. The commentary are applications related to cosmological overall volume and temperature dependence.
Life Prediction and Experimental Validation of a 3d Printed Dental Titanium Ti64ELI Implant
Authors: Lebea Lebogang Clerrence , Ngwangwa Harry , Desai Dawood , Nemavhola Fulufhelo
Published: August 2021

Fatigue analysis plays a vital role in determining the structural integrity and life of a dental implant. With the use of such implants on the rise, there is a corresponding increase in the number of implant failures. As such, the aim of this research paper is to investigate the life of 3D-printed dental implants. The dental implants considered in this study were 3D printed according to the direct metal laser sintering (DMLS) method. Additionally, a finite element model was developed to study their performance, while fatigue life was predicted using Fe-Safe software®. The model was validated experimentally by performing fatigue tests. The life of the dental implants was analysed based on Normal strain and the Brown-Miller with Morrow mean correction factor algorithm. The model revealed that there was a strong correlation between the FEA and the experimental results. The clinical success of 3D-printed dental implant experimentally is 20.51 years and computationally under Normal strain is 19.89 years and Brown-Miller with Morrow mean correction factor is 26.82 years.
Carotenoids in Bacteria: Biosynthesis, Extraction, Characterization and Applications
Authors: López Gerson-Dirceu , Álvarez-Rivera Gerardo , Carazzone Chiara , Ibañez Elena , Leidy Chad , Cifuentes Alejandro
Published: August 2021

Natural carotenoids are secondary metabolites that exhibit antioxidant, anti-inflammatory and anti-cancer properties. These types of compounds are in high demand by pharmaceutical, cosmetic, textile and food industries, leading to the search for new natural sources of carotenoids. In recent years, the production of carotenoids from bacteria has become of great interest for industrial applications. In addition to carotenoids with C40-skeletons, some bacteria have the ability to synthesize characteristic carotenoids with C30-skeletons. In this regard, a great variety of methodologies for the extraction and identification of bacterial carotenoids has been reported and this is the first review that condenses much of this information. To understand the diversity of these carotenoids, we present their biosynthetic origin in order to focus on the methodologies employed in their extraction and characterization. Special emphasis has been made on high-performance liquid chromatography-mass spectrometry (HPLC-MS) for the analysis and identification of bacterial carotenoids. We end up this review showing their potential commercial use of bacterial carotenoids. This review is proposed as a guide for the identification of these metabolites, which are frequently reported in new bacteria strains.
In Silico Study of Silybum Marianum Targeting Parp Protein (4UND Protein)
Authors: Gosavi Hrishikesh D. , Badhe Pravin
Published: August 2021

Silybum Marianum, is a plant belonging to the family Asteraceae. For many centuries it has been used a natural remedy for many diseases like Liver and Biliary tract diseases. It is effective as an anti-oxidant and is used in a variety of diseases. This study was conducted to check the effects of Silybum Marianum on PARP protein (4UND protein).The Molecular Docking techniques was chosen to check the effects of different chemical constituents of Silybum marianum on DNA damaging protein. For this purpose, different PARP inhibitor drugs were taken as standard. The Molecular Docking of the chemical constituents of Silybum marianum was performed using 4UND protein with the help of PyRx software along with BIOVIA Drug Discovery studio software. The result of molecular docking showed that some of the chemical constituent have higher binding affinity than standard PARP inhibitor drugs.
Milk Fermented with Lactobacillus casei Strain AP Improves Lipid Profiles in Obese Indonesian Adults
Authors: Widodo Widodo , Denta Anggeria Oktavisa , Sunarti Sunarti , Haltrich Dietmar
Published: August 2021

Obesity and hyperglycemia can trigger various diseases, including diabetes mellitus and cardiovascular ailments. Health-promoting fermented milk products can be useful in tackling these issues. One such product is the fermented milk developed using Lactobacillus casei AP, a probiotic strain from Indonesia that has not been tested in humans thus far. Our objective was to examine the effects of L. casei AP-fermented milk products on lipid profiles, blood glucose levels and monocyte chemoattractant protein-1 (MCP-1) levels in obese adults. A total of 29 obese subjects were given L. casei AP-fermented milk products, and their fasting blood glucose, total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL) and triglyceride levels were measured using diagnostic system kits. MCP-1 levels were measured using enzyme-linked immunosorbent assay. It was determined that the administration of L. casei AP-fermented milk products significantly reduced total cholesterol, LDL and triglyceride levels (p < 0.05); however, it did not increase HDL (p > 0.05), MCP-1 or fasting blood glucose levels (p ≥ 0.05). In conclusion, in obese Indonesian adults, L. casei AP-fermented milk might reduce total cholesterol, LDL and triglyceride levels but may not affect HDL, MCP-1 or fasting blood glucose levels.
Task-Adaptive Embedding Learning with Dynamic Kernel Fusion for Few-Shot Remote Sensing Scene Classification
Authors: Zhang Pei , Fan Guoliang , Wu Chanyue , Wang Dong , Li Ying
Published: August 2021

The central goal of few-shot scene classification is to learn a model that can generalize well to a novel scene category (UNSEEN) from only one or a few labeled examples. Recent works in the remote sensing (RS) community tackle this challenge by developing algorithms in a meta-learning manner. However, most prior approaches have either focused on rapidly optimizing a meta-learner or aimed at finding good similarity metrics while overlooking the embedding power. Here we propose a novel Task-Adaptive Embedding Learning (TAEL) framework that complements the existing methods by giving full play to feature embedding’s dual roles in few-shot scene classification - representing images and constructing classifiers in the embedding space. First, we design a lightweight network that enriches the diversity and expressive capacity of embeddings by dynamically fusing information from multiple kernels. Second, we present a task-adaptive strategy that helps to generate more discriminative representations by transforming the universal embeddings into task-specific embeddings via a self-attention mechanism. We evaluate our model in the standard few-shot learning setting on two challenging datasets: NWPU-RESISC4 and RSD46-WHU. Experimental results demonstrate that, on all tasks, our method achieves state-of-the-art performance by a significant margin.
Racing and Training Demands of off-Road Triathlon: A Case Study of a National Champion Masters Triathlete
Authors: Harnish Christopher R , Ferguson Hamish A , Swinand Gregory P
Published: August 2021

(1) Background: This report examines the unique demands of off-road triathlon (XT) by presenting physiological, field, and race data from a national champion off-road triathlete using several years of laboratory and field data to detail training and race intensity. (2) Methods: Laboratory and field data were collected when the athlete was at near peak fitness and included oxygen consumption (VO2), heart rate (HR), power output (W), and blood lactate (BLC) during cycling and running, while HR, cycling W, and running metrics were obtained from training and race data files over a period of seven years. Intensity was described using % HR max zones (Z) 1 < 75%, 2 = 75 - 87%, and Zone 3 > 87%, and W. An ordinary least squares analysis was used to model differences between event types. (3) Results: Weather conditions were not different across events. XT events had twice the elevation change (p<0.01) and two-three times greater W’ (p< 0.001) than road triathlon (ROAD), but similar HR intensity profiles (max, avg, and zones); both events are predominately performed at > Z2 or higher intensity. Championship XT events were longer (p<0.01) , with higher kJ expenditure (p<0.001). OLS modelling suggested three variables were strongly related (R2 = 0.84; p < 0.0001) to cycling performance: event type (XT vs ROAD), total meters climbed, and total bike duration. Championship XT runs were slower than either regional (p<0.05) or ROAD (p<0.01) runs, but HR intensity profiles similar. OLS modelling indicates that slower running is linked to either greater total bike kJ expenditure (R2 = 0.57; p<0.001), or total meters gained (R2 = 0.52; p<0.001). Race simulation data support these findings but failed to produce meaningful differences in running. Conclusions: XT race demands are unique and mirror MTB and trail running demands. XT athletes must be mindful of developing anaerobic fitness, technical ability, and aerobic fitness, all of which contribute to off-road cycling economy. It is unclear whether XT cycling affects subsequent running performance different from ROAD cycling.
An Integration of Deep Network with Random Forests Framework for Image Quality Assessment in Real-Time
Authors: Al Chami Zahi , Abou Jaoude Chady , Chbeir Richard
Published: August 2021

In recent years, data providers are generating and streaming a large number of images. More particularly, processing images that contain faces have received great attention due to its numerous applications, such as entertainment and social media apps. The enormous amount of images shared on these applications presents serious challenges and requires massive computing resources to ensure efficient data processing. However, images are subject to a wide range of distortions in real application scenarios during the processing, transmission, sharing, or combination of many factors. So, there is a need to guarantee acceptable delivery content, even though some distorted images do not have access to their original version. In this paper, we present a framework developed to estimate the images' quality while processing a large number of images in real-time. Our quality evaluation is measured using an integration of a deep network with random forests. In addition, a face alignment metric is used to assess the facial features. Experimental results have been conducted on two artificially distorted benchmark datasets, LIVE and TID2013. We show that our proposed approach outperforms the state-of-art methods, having a Pearson Correlation Coefficient (PCC) and Spearman Rank Order Correlation Correlation Coefficient (SROCC) with subjective human scores of almost 0.942 and 0.931 while minimizing the processing time from 4.8ms to 1.8ms.
Special Issue on Nursing Robots and Support Systems for Welfare Sites
Authors: Fujisawa Shoichiro , Takaiwa Masahiro , Hirata Yasuhisa , Kotosaka Shinya , Chugo Daisuke
Published: August 2021

Japan’s population is aging at a speed unprecedented in the world, and its shortage of caregivers has become a major issue. At the same time, the Internet of Things (IoT) is expected to create unprecedented new value by connecting all people and things, allowing them to share various kinds of knowledge and information. In addition, as artificial intelligence (AI) and big data are undergoing a transformation that is changing the value of human labor, robots incorporating these innovative technologies are expected to solve the problems of the aging society. On the other hand, in the field of nursing care, the relationship between the caregiver and the care-receiver is basically a person-to-person connection. There is a question of how people and technology can coexist and produce new creations in such fields.

This special issue on Nursing Robots and Support Systems for Welfare Sites includes one review paper and 23 other interesting papers that cover the following topics:

ı Research on independence support and systems to watch over the elderly.

ı Research on support systems for diet, recreation, medication, etc. for people with dementia.

ı Research on control and sensor systems for vital signs and excretion.

ı Research on rehabilitation equipment for the physically handicapped.

ı Research on assistive technologies for mobility support.

ı Research on upper and lower limb power assistance devices and robots.

We thank all authors and reviewers of the papers as well as the Editorial Board of the Journal of Robotics and Mechatronics for their help with this special issue.
Development and Dissemination of Nursing Robots and Support Systems for Welfare Sites
Authors: Higashi Yuji ,   National Rehabilitation Center for Persons with Disabilities 1 Namiki 4-chome, Tokorozawa City, Saitama 359-8555, Japan
Published: August 2021

The Japanese population is rapidly aging, with fewer proportion of children, and its production-age population has decreased correspondingly, with a resulting shortage in nursing-care service providers. To cope with this situation, the Japanese government has focused on developing and deploying nursing-care robots to compensate for the shortage of human resources. As most nursing-care services are intended for the elderly and disabled, they are traditionally considered as human services. To implement nursing-care robots on a large scale, numerous approaches and measures have been considered, such as modeling the approaches to effectively use nursing-care robots in nursing-care fields, rewarding highly useful nursing-care robots with greater nursing-care compensations, and responding to consultations at nursing-care sites by building a platform to develop, demonstrate, and deploy nursing-care robots. However, nursing-care services using robots are still not popular because of prevailing anxieties about and resistance to such technologies; therefore, the promotion of nursing-care services using robot technologies remains a challenge. Presently, a system capable of supporting not only a single nursing-care scenario but also a series of nursing-care operations is highly desired. In the future, nursing-care services have to be made more rewarding using robots, for which it is vitally important to provide support in the form of evidence-based, scientific, and effective nursing-care services.
Excretion Detection Systems with Gas Sensors – Development of Prototype Devices Integrating Sensor and Operation Functions –
Authors: Sugano Shohei , Ui Yoshimi , Tanimoto Kazushiro , Nakano Kenta , Tomiyama Ken ,   aba Inc. 3-30-5 Maebara Higashi, Funabashi, Chiba 274-0824, Japan,   Future Robotics Technology Center (fuRo), Chiba Institute of Technology 2-17-1 Tsudanuma, Narashino, Chiba 275-0016, Japan
Published: August 2021

In this study, we report on the development and evaluation of new excretion detection devices based on an existing product, Product H, which utilizes odor-sensing technology. Caregivers can use the developed device to receive a detection signal and record the true/false status of the detection. This device is based on a preliminary interview with caregivers regarding the desirable characteristics of the planned device. As a result, the size of the device was reduced to approximately 20% of the existing product. An excretion detection rate of 60% was achieved in a clinical experiment, as compared with that of 80% for Product H. This is significant because the parameter values were not yet optimized for the developed device. Further, a simple questionnaire was administered to caregivers, in which the intuitiveness of the operation and the functionality of the design were praised. However, there is a desire for an option to record more excretion characteristics was expressed. Therefore, we developed a revised device to include an input option regarding the amount and hardness of the excrement. The results of the subsequent evaluation questionnaire on the revised device were mostly favorable, but the caregivers had divided opinions on the new input feature. This result suggests a need for further investigation regarding the necessity of this feature.
Development of a Tele-Rehabilitation System Using an Upper Limb Assistive Device
Authors: Tanaka Eiichiro , Lian Wei-Liang , Liao Yun-Ting , Yang Hao , Li Li-Ning , Lee Hee-Hyol , Shimodozono Megumi ,   Faculty of Science and Engineering, Waseda University 2-7 Hibikino, Wakamatsu-ku, Kitakyushu, Fukuoka 808-0135, Japan,   Graduate School of Information, Production and Systems, Waseda University 2-7 Hibikino, Wakamatsu-ku, Kitakyushu, Fukuoka 808-0135, Japan,   Department of Rehabilitation and Physical Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University 8-35-1 Sakuragaoka, Kagoshima, Kagoshima 890-8544, Japan
Published: August 2021

A tele-rehabilitation system that can achieve remote interaction between a physical therapist (PT) and a patient was developed. Patients need to execute rehabilitation exercises to maintain upper limb function. However, it is difficult for them to travel to hospitals without aid. This system is equipped with a PC and a Kinect sensor at the hospital side (i.e., the PT), and a PC and an upper limb assistive device in the patient’s home. The PT displays the motion in front of a Kinect sensor, which identifies the motion. In addition, the device on the home side assists the motion of the patient using the Internet. When the device receives a force higher than the safety value from the patient at any particular point on it, vibrators at the corresponding point on the PT’s arm start to vibrate. Thereby, the PT can identify the patient’s condition and limitations. The time delays in the transmission of data of device motion and the vibrators were measured and compared. As a result, the PT could identify the patient’s condition faster than the motion of the device.
History of Methadone and Buprenorphine Opioid Agonist Therapy Among People Who Died of an Accidental Opioid-Involved Overdose: Rhode Island, January 1, 2018–June 30, 2020
Authors: Hallowell Benjamin D. , Weidele Heidi R. , Daly Mackenzie , Chambers Laura C. , Scagos Rachel P. , Gargano Lisa , McDonald James
Published: August 2021

To guide intervention efforts, we identified the proportion of individuals previously engaged in opioid agonist therapy among people who died of an accidental opioid-involved overdose. Most individuals (60.9%) had never received any prior buprenorphine or methadone treatment. Individuals who died of an overdose in 2020 had a similar demographic profile and treatment history compared with prior years. To prevent additional accidental opioid-involved overdose deaths, efforts should be directed toward linking individuals to care.
Allegorical analysis of social life
Authors: Mohira Islomova
Published: August 2021

In the article the influence of the ancient Indian epic on world literature is reflected in the scientific analysis of the reflection of events in public life, interpersonal and social relations through symbolic and figurative characters, allegorical heroes.
Giving Positive Reinforcement to Reduce Aggressiveness in Children with ADD
Authors: Nurdiyanto Muhamad Fadlullohil Hakim
Published: August 2021

Attention Deficit Hyperactivity Disorder (ADHD) is a medical condition, which is characterized by hyperactivity, inability to focus attention and impulsivity, which is persistent. The location of this research is located at SDN Jimbaran Wetan. The child is male and he is currently seven years old. ADHD children now sit in the first grade of Jimbaran Wetan Elementary School. The purpose of this study was to determine the effect of giving positive reinforcement to the decrease in aggressiveness in ADHD children. The variables of this study are positive reinforcement as an independent variable (X) and aggressiveness as a dependent variable (Y). The Positive Reinforcement Method is a method in which the child with ADHD is given a task to control himself and if the task can be done then the child gets a reword that has been agreed upon in advance, such as if the child shows a good attitude on that day then the child gets a toy gift. This study uses a qualitative experimental approach with within-subject research, namely the type of experimental research that examines an individual's behavior, makes observations, and set a baseline, then intervenes. After the intervention, the researcher made another observation to determine the effect of the intervention. Observations were made just before the intervention, during the intervention and after the intervention using the aggressiveness check list. In filling out the check list, researchers involve class teachers to help control and supervise children with ADHD. Class teachers are also involved to fill the aggressiveness check list so they can find out about changes in the daily behavior of ADHD children in the intervention process. From the results of data analysis it was found that there was a decrease in aggressiveness in children with ADHD. This is indicated from the aggressiveness check list which illustrates that the aggressiveness behavior is increasingly decreasing.
"Internet of Things (IoT) Based Disinfectant Spray Robot and Camera ESP 32"
Authors: Muchyiddin Moh Imam , Sulistiyowati Indah
Published: August 2021

This document describes guidelines for Authors in writing an article in UMSIDA. This abstract section should be typed in Italic 10 pt font and number of words of 100-150. If the article is written in Indonesian, the abstract should be typed in English and Indonesian. Meanwhile, if the article is written in English, the abstract should be typed in English only. The abstract should be typed as concise as possible and should be composed of: problem statement, method, scientific finding results, and a short conclusion. The abstract should be typed in one paragraph only and two-columns format. All sections in the manuscript should be typed using Times New Roman font. Authors should use this document as their article template.
Automation of eWeLink Based Fresh Bread Dough System
Authors: Sofyan Muhammad , Rasjid Saputra Dwi Hadidjaja
Published: August 2021

The process of plain bread dough without sugar after the fermentation process is then left to stand for a certain time manually or modern. The process of developing plain bread dough without sugar can be done by using yeast which is widely sold in the market. The yeast is mixed evenly into the dough, then covered with a cloth and left for a certain time until the dough of plain bread without sugar expands. The factors that influence the development of unsweetened bread dough are the right amount of yeast, temperature and humidity also determine the development process of the bread dough without sugar. If the supporting factors are not suitable, it can cause the plain bread dough without sugar to fail to expand. By using the automation system for bread dough without sugar based on ewelink, it can reduce the failure rate during the development process of bread dough without sugar with optimal results.
IoT Based Smart Cupboard Design
Authors: Atmojo Trio , Dhiya Shazan , Sulistyowati Indah , Wicaksono Arief
Published: August 2021

During the rainy season, the clothes can dry for 1 day or more. Often times when on the way home from work or school it is trapped in rain so that the clothes used are little damp, because the clothes are still used for tomorrow so the clothes are not possible to wash and can dry overnight. easy to open or break into by anyone, given the habit of people used to storing valuables in the cupboard, an extra security system is needed. Then a IOT-Based Smart Cupboard Design is made which aims to improve the function of a conventional wardrobe to be multifunctional, which is equipped with a damp clothes dryer feature and is equipped with a Fingerprint sensor which can only be accessed by the owner to open the wardrobe. to be equipped with a Fingerprint, which functions as extra security in opening cabinets where valuables are usually found. Also equipped with a fan and heater incubator functions in drying damp clothes. This tool is equipped with an IoT which functions as an On Off control for the fan and an incubator heater in heating damp clothes.
ANDROID-BASED APPLICATIONS FOR CHILDREN'S LEAF RECOGNITION LEARNING
Authors: Putra Teguh Hardianto , Eviyanti Ade
Published: August 2021

Indosesia is a country with abundant natural wealth. Almost all types of plants can be grown in the territory of Indonesia. Most have been used in the past to treat various diseases. Therefore, the author wants to design and build a leaf recognition learning application in android-based children that aims to make the younger generation know the diversity of plant leaves in the surrounding environment, in order to make the younger generation understand the need to care for and maintain the natural environment and knowledge about plants that are very important for human life, especially for human health, among others, traditional medicine that is now beginning to fade. This application has ease of use because it has an easy to understand design and a menu that is easy to understand by all people in accessing this application. In this study the author used waterfall method as the process or flow of the research to be done. The test results of the application that has been created get the result that all features and functions of the system can run according to what has been designed. In addition, the author also conducted tests using the UAT method to get a result of a percentage value of 96% so that it can be concluded that this application can be accepted by users.
Implementation of Quality Filter Mapping (QFM) in Hot Press Using Lean Manufacturing To Eliminate Waste
Authors: Muhamad Yasin  , Lukmandono
Published: August 2021

PT Sakari Sumber Abadi is a manufacturing company that is engaged in producing plywood products as its main product. This company has waste in the production line, namely in the 4.6 mm Birch product, including shrinkage putty, press mark, tip delemination, bubbles, ripping. Whereas for 18 mm Birch products, among others, press marks, putty shrinkage, concave, overlap, putty face too wide, ripping, waste in the face and delamination of the ends. What you want to achieve in this research is to eliminate the waste of 4.6 mm Birch Products and 18 mm Birch Products found in the Hot Press section in order to fulfill customer demand with the Lean Manufacturing approach. Lean Manufacturing is a systematic approach that eliminates waste and transforms processes. The results of the inspection using the Quality Filter Mapping (QFM) method obtained the largest waste in the Birch 4.6 mm Face 0.5 mm product, namely Failure to Riject by 0.82% and on Birch 18 mm Face 0.28 mm product, namely Failure to Riject by 7.1%. Recommendations for improvement include standard parameters of temperature, press time and pressure.
Red Sea Holocene carbonates: Windward platform margin and lagoon near Al-Wajh, northern Saudi Arabia
Authors: Steinhauff D. Mark , Abubshait Abduljaleel , Purkis Sam J.
Published: August 2021

Analysis of Holocene sedimentary seascape is focused on the Red Sea windward Al-Wajh platform margin, its central lagoon, and nearby isolated platforms based on data that include mapped ecological facies (habitats), water depths, grain sizes, and allochem types and abundances determined from thin sections. On this basis, a depositional model applicable to Red Sea Plio-Pleistocene and other ancient icehouse carbonate platforms is presented. The model highlights favorable reservoirs in analogous ancient systems to include coral crests and columnar framework habitats with primary porosity developed in boundstone lithologies and windward platform margins to contain considerable open pore space, including cavernous openings, of which not all should be anticipated to be occluded with marine cements and sediments. Meteoric diagenesis is expected to be minor as limited freshwater is available due to extreme aridity, but may play a role during glaciation.

Most habitats have potential for secondary (enhanced) porosity resulting from dissolution of aragonite skeletons, particularly mollusk shells and calcareous coral (Scleractinia) endoskeletons. Central-lagoon habitats are expected to have the least favorable reservoir potential of environments considered because they are dominated by peloids. Central-lagoon sediment differs from other published localities, having higher peloid abundances, greater peloid distribution, and little or no association with Halimeda and quartz grains. Under the likely scenario that platform-interior sediments are completely bioturbated and comprise peloid-rich, grain-dominated fabrics, with many smaller peloids (most of them likely fecal pellets) at or near 4 μm in size (i.e., mud fraction), it is possible that grain size will control pore size once the considered deposits are lithified. If so, platform-interior sediments will lithify as mudstones, wackestones, or very fine-grained grainstones, an outcome which might otherwise be unexpected given the abundance of coarse peloid grains.

The Al-Wajh platform is compared with 15 Holocene analogs and found to be unique with respect to rift-margin type, restricted-marine circulation, in having a lagoon with high peloid content, and lack of karst. In further comparison with ancient reservoir analogs, two greenhouse and four icehouse, it compares favorably to icehouse platforms deposited in rift basins with respect to mineralogy of deposition, meter-scale cycle thicknesses, and general peloid content and distribution. It provides a snapshot as to how an icehouse platform might have nucleated and attached along an active rift margin; it is a broadly applicable carbonate analog for the Red Sea Plio-Pleistocene and similar icehouse, rift basins.
Methodology «8D» as a tool for managing logistics costs for mechanical engineering enterprises
Authors: Hulevich Yu. N. , Nalivaiko G. M.
Published: August 2021

Described “8D” to solve the problems of logistics and quality at the machine-building complex. The technique is designed for organizations operating in the B2B market in the supply chain. Software based on 1C Enterprise allows you to apply the technique of 8D to identify the root causes of the discrepancy and to develop measures to address them in order to prevent recurrence. Standardizing this technique and implementing it through appropriate software used by organizations throughout the supply chain is a productive tool for achieving economic benefits.
ТЕНДЕНЦИИ РАЗВИТИЯ МАЛОГО И СРЕДНЕГО БИЗНЕСА В БЕЛАРУСИ
Authors: ТЕЛЕГИНА О.
Published: August 2021

В статье приведены критерии отнесения предприятий к малому и среднему бизнесу. Оценена роль бизнеса в основных экономических показателях. Рассмотрена структура производства малого и среднего бизнеса по отраслям экономики, определен их вклад в отрасли промышленности. Дана оценка институциональной среды ведения бизнеса в Беларуси. Обозначены основные факторы, сдерживающие рост бизнеса.
МАТРИЧНАЯ МОДЕЛЬ УПРАВЛЕНИЯ БИЗНЕС-ПРОЦЕССАМИ ОРГАНИЗАЦИИ НА ПРИМЕРЕ ПИЩЕВОЙ ПРОМЫШЛЕННОСТИ
Authors: РОДЦЕВИЧ О.
Published: August 2021

В статье рассматривается промышленная организация как элемент макросреды, взаимодействующий с рынками покупателей и поставщиков. Акцентируется внимание на изменение управленческих технологий, которые должны быть направлены на повышение уровня конкурентоспособности предприятия. Универсального алгоритма для создания системы эффективного управления промышленными организациями не существует, однако возможна разработка общих принципов построения подобных систем управления бизнесом. К числу наиболее передовых методов
построения систем эффективного управления можно отнести процессный подход.
В рамках процессного подхода к управлению организацией, в статье предлагается построение матричной модели для совершенствования управления бизнес-процессами на примере предприятий пищевой промышленности. Особенностью модели является то, что сформированная матрица дает возможность определить задачи уровня организационного подразделения (отдела), которые затем могут группироваться как по функциональному (по предмету деятельности) или процессному (по результату) принципам, так и по рыночному событию.
ЭВОЛЮЦИЯ ПОНЯТИЯ «УСТОЙЧИВОЕ РАЗВИТИЕ» В ЭКОНОМИЧЕСКОЙ НАУКЕ
Authors: МАЗУРЕНКО О.
Published: August 2021

В статье изложены основные теоретические подходы к трактовке понятия «устойчивое развитие», определены особенности его формирования и развития.
ЭНДОГЕННЫЕ ФАКТОРЫ, ОБУСЛОВЛИВАЮЩИЕ РАЗВИТИЕ ПРОМЫШЛЕННОЙ ПОЛИТИКИ БЕЛАРУСИ В СОВРЕМЕННЫХ УСЛОВИЯХ
Authors: ГУРСКИЙ В.
Published: August 2021

Наличие определенных противоречий на нынешнем этапе развития промышленности Беларуси требует пересмотра основных направлений и инструментов промышленной политики. На основании учета особенностей белорусской модели экономического развития выявлены и систематизированы факторы, обусловливающие формирование и эволюцию промышленной политики в Беларуси. Представлен механизм действия факторов, обусловливающих формирование и эволюцию промышленной политики в Республике Беларусь.
ИНСТИТУТЫ РАЗВИТИЯ: МИРОВЫЕ ТРЕНДЫ И НАЦИОНАЛЬНЫЕ ПРОБЛЕМЫ
Authors: ЛЕМЕЩЕНКО П.
Published: August 2021

Статья посвящена не совсем обычному и привычному для исследователя экономическому ресурсу – институтам и институциям, которые, с одной стороны, инициируют, организуют в той или иной степени эффективности использование этих традиционных ресурсов, а, с другой – сами впитывают и оформляют результат социальноэкономического и нравственно-культурного развития, создавая потенциал к развитию на следующем историческом цикле эволюции. Предмет исследования, таким образом, это область устойчивых политико-культурных и социальнопсихологических отношений, создающие потенциальные условия и возможности страны к развитию и росту, а также устанавливающие при определенных обстоятельствах и проявляющихся интересах серьезные ограничения политико-экономической динамики. Цель работы заключается в том, чтобы зафиксировать российский исторический контекст эволюции с формальными проявлениями, инициированными различными внутренними и внешними институтами. Сделан вывод о необходимости проведения эволюционной динамики как наиболее оптимальной с точки зрения трансформационных издержек, предполагающей сочетание экономической генетики и имеющихся в стране ментальных свойств с формальным институциональным регулированием. Реформы последних десятков лет, а также текущая санкционная война ориентируют на стратегию регионализации и формирование политикоэкономических союзов стран, близких по ментальным признакам населения, политиков, бизнеса.
МАКРО- И МЕТАЭКОНОМИЧЕСКИЕ ТЕНДЕНЦИИ В РАЗВИТИИ ЛОГИСТИЧЕСКОЙ ИНФРАСТРУКТУРЫ
Authors: ЛАВРЕНТЬЕВ П.
Published: August 2021

В статье дается оценка состояния логистической системы и ее значимости для мировой экономики. Проводиться анализ логистической среды Республики Беларусь в разрезе мировых контейнерных перевозок с точки зрения формирования национальной логистической инфраструктуры, а так же влияния состояния инфраструктуры на внутренний и транзитный товарный поток, проходящий по территории Беларуси.
АНАЛИЗ ИННОВАЦИОННОЙ АКТИВНОСТИ ПРЕДПРИЯТИЙ
Authors: МАШЕВСКАЯ О.
Published: August 2021

Раскрыта сущность инноваций, представлена к рассмотрению характеристика инноваций и их особенности в рамках жизненного цикла. Установлено, что в сложившихся условиях возрастает роль инноваций, как на мировом, так и на межрегиональном рынке, а значит, усиливается актуальность выработки адекватной инновационной политики. Проведен анализ инновационной активности на микроуровне (предприятий) в Республике Беларусь и России, дана оценка их масштабов деятельности и предложены направления совершенствования и разработки инноваций.
Lack of association between patients characteristics and carriage of extended-spectrum β-lactamase producing Enterobacteriaceae in community settings in Blantyre, Malawi
Authors: Onduru Onduru Gervas , Rumisha Susan Fred , Mkakosya Rajhab Sawasawa , Bunduki Gabriel Kambale , Aboud Said
Published: August 2021

Background: Infections caused by extended-spectrum β-lactamase (ESBL) producing bacteria are global health threat contributing to increased morbidity and mortality in resource-constrained countries. This cross sectional study examined factors associated with the carriage of ESBL-producing Enterobacteriaceae (ESBL-E) in community patients in Blantyre, Malawi. Methods: We collected rectal swabs and urine samples from randomly recruited participants and screened for ESBL-E on CHROMagarTM ESBL medium (CHROMagar, Paris, France). The ESBL-E isolates were identified using commercially acquired biochemical strips (Microbact™ GNB, Oxoid, UK) and production of ESBL was confirmed by the combination disk test using cefotaxime and ceftazidime disks with and without clavulanic acid. Antibiotic susceptibility test was done by the disc diffusion method and interpreted according to the recommendations of the Clinical and Laboratory Standards Institute (CLSI) 2019. Univariate logistic regression was used to evaluate association between ESBL-E carriage and the assosiated factors. To quantify relationships, dichotomous variables were compared using Pearson’s chi-square test or Fisher exact test as appropriate and continuous variables were compared using the Student’s t-test. Results were expressed as odds ratio (OR) with a 95% confidence intervalResults A total of 50 community patients with ESBL-E phenotypes were identified from 300 adults recruited in the study, which gave a ESBL-E prevalence of 16.67% (50/300, 95% CI=12.43-20.91%). The mean age ±SD of participants was 32.41±12.07 years; range, 18-75 years and 54.33% (163/300) were women. on unadjusted logistic regression, no association between carriage of ESBL-E and community patient characteristics was observed.Conclussions The carriage of ESBL-E is prevalent in the community in Blantyre-Malawi. Nevertheless, factors associated with this carriage remain unidentified. Further investigations including large case-control and molecular studies using one health approach are required to confirm community-based transmission of ESBLs and to determine the factors, reservoirs and vehicles associated with the dissemination of ESBL within the community in Blantyre, Malawi.
Impact of a Novel Approach for Undergraduate Medical Ethics Education in The Middle East and South Asia
Authors: Shamim Muhammad Shahid , Baig Lubna , Torda Adrienne , Balasooriya Chinthaka
Published: August 2021

Background

Complexities of ethics education, combined with socio-cultural issues specific to the medical curricula of the developing country context, have created resource constraints that impact medical ethics education delivery in countries like Pakistan and Saudi Arabia. These constraints include the dearth of contextually relevant texts, shortage of trained teachers and confines in institutional regulations in the regions. Focused strategies are required to address these constraints. Workbook-based ethics learning (WBEL) is one such strategy based on a contextually relevant ethics education model.
Purpose

This study aimed to evaluate the effectiveness of ethics education, delivered through the WBEL strategy, on students’ learning and satisfaction in medical colleges of Pakistan and Saudi Arabia.
Methods

A pre-post-test intervention study was conducted in two medical colleges, Jinnah Sindh Medical University, Pakistan and King Abdulaziz University, Saudi Arabia. An ethics course was structured using the WBEL strategy and delivered to early clinical years medical students. The impact on student learning was measured by pre-and-post administration of a set of Key Feature Questions (KFQ) and a Script Concordance Test (SCT). A twenty-eight-item course feedback questionnaire was developed to collect students’ perceptions regarding the WBEL strategy.
Results

Of the total 125 students who consented, 90 (72%) completed the pre-and post-test measures, and 103 returned the feedback forms at the two sites. The post-test scores in KFQs were significantly higher than pretest scores in both Pakistani and Saudi students (p-value < 0.001). There was no significant pre-to-post difference in overall SCT scores (p = 0.057). The majority of participants considered the overall course to be valuable. They provided positive feedback on the Workbook’s usefulness and the enhancement of critical thinking within the course. Ethics case discussions, classroom quizzes, and reflective writing were considered most effective for learning during the course.
Conclusion

The findings suggest that the WBEL is a promising way forward in medical ethics education as it resulted in a notable increase in participants’ knowledge and ethical decision-making skills. The study also provides evidence of feasibility for using the WBEL strategy for teaching ethics in resource-limited regions.
A Randomized Controlled Trial Study on Hypertension Reduction Based on Disease Control Priorities to Manage High Blood Pressure
Authors: Khan Subhana Akber , Khan Shahzad Ali , Hafeez Assad , Zaka Arif
Published: August 2021

BackgroundOne of the global targets for non-communicable diseases is to reduce the prevalence of hypertension by 25% by year 2025. In Pakistan, prevalence of hypertension is reported to be 24.9% among males and in females the prevalence is 24.7%. The purpose of this study was to test the deliverability of a multicomponent based intervention for reduction of high blood pressure to recommended 140/90 mm of Hg and to test its effectiveness in control of hypertension among hypertensive patients.MethodsUsing a randomized controlled trial, double blinded study design, the intervention was pilot-tested for its appropriateness for implementation in hospital. The intervention was given to hypertensive patients in the intervention group. A total of 240 participants were screened and recruited into the trial after obtaining an informed consent. An ethical approval was sought from Health Services Academy. Data was collected from December 2019 to March 2020. All the data was entered and analyzed uing SPSS version 21.ResultsImplementation of a multi-component intervention to test DCP3 based strategies for management and control of hypertension in a hospital setting during three months yielded – 23.9 mm Hg of systolic blood pressure reduction (95% confidence interval, p ≤ 0.005). A significant reduction in the blood pressure to recommended target in intervention group was achieved in 6th, 8th and 12th week. As compared to patients in usual care group, improved health outcomes were achieved for diet control, reduction in salt intake and an increased physical exercise among hypertensive patients. Regular follow up and strict adherence to prescribed medicines was observed in both groups.ConclusionStudy findings concluded that the multicomponent intervention particlulary use of low salt and lifestyle modifications is effective in hypertension reduction. Involving family members of the patient was an essential component of non-pharmacologocal treatment which was found to be beneficial for management and control of hypertension.Trial registration: The study was registered in clinicaltrials.gov number NCT04336631 dated April 07, 2020.
Diagnostic Performance of Noninvasive Imaging Modalities for Localization of Insulinoma: A Meta-Analysis
Authors: Yang Yi , Shi Jian , Zhu Jianbing
Published: August 2021

BackgroundInsulinomas is the most common functional neuroendocrine tumor found only in the pancreas. The early detection of insulinoma is of importance. Studies comparing the performance of noninvasive modalities were limited by sample size and heterogeneity between studies. The aim of this meta-analysis was to evaluate the diagnostic performance of PET/CT, SPECT/CT, CT and MRI for the localization of insulinoma, and to provide evidence for clinical practice.MethodsPubMed, Embase, Cochrane Library, Wanfang Data and China National Knowledge Infrastructure were searched from inception to May 31, 2021. Pooled sensitivity, specificity, positive Likelihood Ratio (+LR) and negative Likelihood Ratio (-LR), diagnostic odds ratio (DOR), and concordance rate were calculated.ResultsA total of 19 studies including 708 patients of insulinoma reached the inclusion criteria. PET/CT imaging demonstrated a pooled sensitivity of 0.79 (95% CI: 0.54–0.92) and a pooled specificity of 0.84 (95% CI: 0.20–0.99). The pooled sensitivity and specificity of SPECT/CT were 0.77 (95% CI: 0.46–0.93) and 0.45 (95% CI: 0.22–0.70). CT showed an overall sensitivity of 0.54 (95% CI:0.35–0.72) and specificity of 0.75 (95% CI: 0.54–0.88). The pooled sensitivity and specificity for MRI were 0.54 (95% CI: 0.31–0.75) and 0.65 (95% CI: 0.39–0.84), respectively. The concordance rates of PET, SPECT, CT, and MRI were 78% (95% CI: 66%-90%), 74% (95% CI: 52%-97%), 56% (95% CI: 41%-72%), and 53% (95% CI: 33%-73%), respectively.ConclusionResults of this study indicate that PET/CT demonstrated superior performance than SPECT/CT, CT and MRI for the localization of insulinoma. GLP-1R based PET/CT manifested better diagnostic performance in comparison with SSTR based PET/CT imaging modality.