bluuebunny/crossref_metadata_2025 huggingface dataset:
Analyzing global renewable energy generation trends amid volatile economic and social environments
Authors: Wei Ziheng , Wei Zirui , Huang Jason
Published: June 2023

As renewable energy (RE) rapidly integrates into society to meet the growing demand for affordable and clean energy (SDG 7, United Nations’ Sustainable Development Goal 7), it is crucial to analyze the merits and flaws of renewable energy generation by assessing its impact on the global economy and social wellbeing. This paper performs an investigative study on the correlation and causality between renewable energy, economy, and environmental indicators. The data was gathered from diverse sources, including The Center for Climate and Energy Solutions, National Aeronautics and Space Administration Goddard Institute for Space Studies (NASA GISS), and Our World in Data, for the temperature, carbon dioxide (CO2) emissions, and gross domestic product (GDP) data. Significant Granger p-values were obtained for RE generation’s ability to forecast CO2 emissions and temperature, while discovering a strong positive correlation between CO2 and RE generation. The findings revealed that RE has limited effects on the global economy but has considerable implications on social and ecological well-being.
Cerebrovascular Changes and Cerebral Atrophy in the Development of Dementia during Alzheimer's Disease
Authors: Maksimovich Ivan
Published: June 2023

Background: Alzheimer's disease (AD) is the world's number one cerebral neurodegenerative disease. Up to 80% of all dementia cases are due to this disease. AD occurs not only because of impaired metabolism of amyloid beta (Aβ) and tau protein in cerebral tissue, but also in connection with specific disorders of cerebral blood supply, manifested in dyscirculatory angiopathy of Alzheimer's type (DAAT). Aims: The present research focuses on the clinical discovery of the sequence of development of dyscirculatory angiopathy of Alzheimer's type, cerebral atrophy, and dementia in patients with AD and their immediate family members. Methods: 99 patients were selected for the research, of whom: Test Group 1 93 (93.94%) suffered from various stages of AD and severity of dementia (age 34-79 (mean age 67): 32 (34.40%) men, 61 (65.59%) women). Test Group 2 6 (6.06%) children aged 8-12 with a high probability of inheriting AD. Each of them had a parent diagnosed with AD with mild dementia (TDR-1), and a grandparent diagnosed with AD with moderate (TDR-2) or severe dementia (TDR-3). Each child complained of fatigue, memory loss, difficulty in remembering, difficulty in concentrating, and frequent headaches. Results: Test Group 1. According to the severity of dementia and atrophic changes in the temporal lobes, the patients were subdivided: preclinical stage TDR-0 - 10 (10.75%) people, mild stage AD TDR-1 - 26 (27.96%) people, moderately severe stage AD TDR-2-40 (43.01%) people, severe AD TDR-3 - 17 (18.28%) people. We identified dyscirculatory angiopathy of Alzheimer's type in all patients, regardless of their AD stage. Test Group 2. There were no signs of dementia of cognitive disorders in any case. Initial involutive cerebral changes were detected in all 6 (100%) patients. Phenomena similar to DAAT were detected in all 6 (100%) patients. Conclusion: Cerebrovascular changes manifested by dyscirculatory angiopathy of Alzheimer's type, regardless of the stage of the disease, are observed in all patients with AD, as well as in all their young offspring. These changes affect amyloid beta metabolism in the brain and contribute to its deposition and accumulation in cerebral tissue, which leads to neurodegeneration and AD development. The data obtained indicate that dyscirculatory angiopathy of Alzheimer's type is primary and, moreover, possibly congenital in AD development.
Psychosocial Basis of Human Sufferings and Poverty in Patients with Neurological and Psychiatric Disorders
Authors: Dubey Souvik , Ghosh Ritwik , Dubey Mahua , Das Shambaditya , Chakraborty Arka , Santra Arindam , Dutta Ajitava , Roy Dipayan , Pandit Alak , Roy Biman , Das Gautam , Benito-León Julián Benito-León,
Published: June 2023

Neurological disorders and psychiatric ailments often lead to cognitive disabilities and low attainment of education, pivoting misconceptions, myths, and misbeliefs. Poverty and low educational attainment are intriguingly associated with poor awareness and perception of these diseases that add to the suffering. Poverty goes parallel with a low level of education and is intricately associated with neuropsychiatric ailments, which have the potential to spread transgenerationally. Robust education policies, proper government rules and regulations against the spread of disease-related myths and misconceptions, uplifting medical education in its true sense, voices against consanguinity, and programs to raise scientific perception about diseases can help to throw light at the end of this dark tunnel. In this article, the authors intend to 1) decipher the potential psychosocial basis of human suffering and poverty in patients with neurological and psychiatric disorders, and 2) discuss the apropos way-outs that would potentially mitigate suffering, and alleviate the economic burden and cognitive disabilities of families with neuropsychiatric diseases.
Necrotizing Pancreatitis: A comprehensive review of the presentation, management, and complications
Authors: Trad George , Zackria Rasiq , Basit Syed , Ryan John
Published: June 2023

Necrotizing pancreatitis (NP) is a life-threatening complication of acute pancreatitis. It requires an extended hospital stay, aggressive management, and has a higher risk of mortality. Risk factors such as comorbidities in the patient’s history including history of coronary artery disease and cerebrovascular disease can increase the risk of developing necrotizing pancreatitis. The presentation of necrotizing pancreatitis is similar to acute pancreatitis, but specific labs such as hematocrit level can be monitored to anticipate the development of necrotizing pancreatitis. In addition, diagnostic imaging must be obtained to classify necrotizing pancreatitis and aid in management choice. Fluid hydration, adequate pain management, and nutritional support are the principles of treating necrotizing pancreatitis. Deciding whether to drain the necrotic collection or not is usually determined based on the type of necrosis present and whether it is infected. Infected necrotizing pancreatitis can also occur, and patients usually need to be monitored closely with appropriate antibiotics for a long duration. Patients affected by necrotizing pancreatitis can potentially develop complications that can lead to devastating outcomes. Necrotizing pancreatitis complications can occur due to an inflammatory reaction on the adjacent structure such as splanchnic vein thrombosis, gastrointestinal fistula or inflammatory reaction within the pancreas leading to an exocrine and an endocrine pancreatic insufficiency. We present here a literature review of necrotizing pancreatitis and the complications that can arise from it.
Rupiah exchange rate: the determinants and impact of shocks on the economy
Authors: Pratiwik Erida , Prajanti Sucihatiningsih Dian Wisika
Published: June 2023

The repetition of policy dynamics on Quantitative Easing (QE) and interest rate by The Fed potentially cause fluctuations in the exchange rate, including in Indonesia. Therefore, this study aims to analyze the determinants and impacts of exchange rate shocks. Inflation (INF), Money Supply (LJUB), Open Market Operations (OPT), Foreign Exchange Reserves (LCD), Expected Inflation (LEHU) and Interest Rates (SB) were used to analyze the determinants of Exchange Rate (NT) through Auto Regressive Distributed Lag (ARDL). The impact of NT shocks was analyzed using Vector Auto Regressive (VAR) by LEHU, Residential Property Price Index (PIHPR), Stock Transactions (LTRANS), and Banking Credit Volume (VK). The Expected Inflation variable and incorporation of ARDL-VAR are novelties in this study. In the secondary time series data for 2014M1 – 2022M9 period, the ARDL results showed that INF and LJUB had positive effect on NT in both long and short run, while OPT, LCD and SB had negative effect. LEHU had negative effect in the short run, but positive in the long run. The speed of adjustment in the model was 49.86% per month. Shock of NT had impacted VK until 15 months, PIHPR at 7 months, LTRANS at 10 months, and LEHU at 14 months. Based on these results, it can be implied that the monetary authority must maintain stability of NT, especially by INF and LJUB transmission. Next, shock's impact must also be overcome, especially on VK. This research is only focused on monetary sector, further research will be refined with other macroeconomic variables.
Ameloblastoma- Guide to an updated short review on the odontogenic neoplasm of the oral cavity
Authors: Gupta Anjali , Singh Siddharth Kumar , Mathur Tushar , Roy Sayak
Published: June 2023

Ameloblastoma, the word has developed from the very early English words that are— ‘Amel’ meaning enamel, and ‘blastos’— meaning the germ. It is a benign locally aggressive neoplasm originating from the odontogenic epithelium. It is also the most common odontogenic neoplasm in the oral cavity.
Young People's Expectations Towards a High School Catechist − Research Report
Authors: Zubrzycka-Maciąg Teresa
Published: June 2023

English translation. The original article can be found here

Religion teachers play a unique role in educating the young generation. In addition to the tasks assigned to all teachers in general, they are to support students in their spiritual development, conditioning their ability to understand themselves, build their own identity, and give meaning to their lives. Catechists face a difficult task, because young people, although they are very interested in religion and spirituality, also have many doubts, questions, and dilemmas in this sphere. The article aims to present the expectations of high school students towards catechists related to their personality traits, skills, psychosocial competencies, and their approach to pupils. Data obtained in a survey conducted with a group of 70 high school graduates show that young people need a catechist whom they can trust in the most important matter, which is the meaning of human life. Thus, they expect catechists to give a credible testimony of faith, have good substantive preparation, treat them subjectively like partners, and are ready to undertake an open dialogue with them.
A 28-Day Repeated Dose Toxicity Evaluation of Creatinine Monohydrate and β-Hydroxy β-Methyl Butyrate Combination in Rodent Model
Authors: Balasubramanian Shivaramakrishnan , Giridharan Kavitha , Kavya K. D. , Vellaipandi Venkataram , Balasubramanian Gurumurthy
Published: June 2023

Substance abuse is a global concern, having a significant influence on society, healthcare, and the economy. Athletes are increasingly using substances to improve their performance or to cope with stress. Therefore, having a thorough awareness of the often misused substances, their effects, and potential toxicities is essential. One such chemical is the mixture of Creatinine Monohydrate (CM) and -Hydroxy Methyl Butyrate (HMB), which is widely used by athletes to increase strength and performance. According to studies, the combination can boost athletic performance, build muscle, and offer several health advantages. To determine the chemicals’ long-term impacts on human health, more research is required because their safety and toxicity are not well-established. Using TOPKAT(Computer-Aided Toxicity Prediction) and Discovery Studio Version 4.0, this study examined the toxicity and pharmacokinetic profiles of CM and HMB. The interaction of HMB and CM may significantly reduce cell viability compared to either drug alone. There were no negative effects seen in the animal models used for the acute oral toxicity study, but additional research is needed to confirm these results and determine the compounds’ long-term safety for human use. The study also performed cytotoxicity studies of individual substances and combinations on VERO and HEP-G2 cell lines and a 28-day repeated dose toxicity study in Wistar albino rats. The study results provide valuable information for healthcare professionals to understand the physiological complications of exposure to such drugs. Overall, the article emphasizes the importance of understanding the potential toxicity of chemical compounds, particularly those used as nutritional supplements.
Therapeutic Protection of Arsenic-Induced Oxidative Stress and Hepato-Nephro Toxicity by Syzygium cumini (Seed) Ethanolic Extract (SCEE) in Charles Foster Rats
Authors: Shankar Prabhat , Singh Rana Vikram , Kumar Arun
Published: June 2023

Arsenic (As) is an environmental toxin distributed in groundwater which is presently a global concern. The present study aimed to investigate the efficacy of SCEE in the mitigation of arsenic-induced hepato-renal dysfunction and oxidative stress in rats. Thirty male Charles foster rats (140-160 g) were randomly assigned into three groups. Group I (n = 6) - Control, Group II (n = 6) - SCEE control was administrated with 600 mg kg-1 body weight daily for 60 days and the last Group III (n = 24) was As-treated at 8 mg kg-1 body weight daily for 90 days. Subsequently, Group III was further divided into three subgroups. The subgroup I (n = 6) was immediately sacrificed to observe the arsenic-induced toxicity. Subgroup II (n = 6) was kept on a normal diet for 60 days for auto recovery. Subgroup III (n = 6) was administrated orally by SCEE at 600 mg kg-1 body weight daily for 60 days to decipher the therapeutic potential against arsenic-induced toxicity. The experimental exposure reveals various changes in biochemical parameters of the liver function test and kidney function test in addition to histopathological studies. Chronic exposure to arsenic significantly (p < 0.0001) increased the levels of lipid peroxidation along with significantly reducing the activity of glutathione, superoxide dismutase and catalase. Significant (p < 0.0001) arsenic accumulation was observed in the hepatic-nephron tissues. The dose-dependent SCEE administration against Astoxicity had progressive survival benefits on antioxidant levels, enzymatic activities and histopathological changes. Thus, the study concludes that S.cumini seed has a protective effect against As-induced oxidative stress and hepato-renal intoxication.
Implementation of Islamic Approach-based Curriculum in Madrasah Ibtidaiyah (MI) Boarding School to Strengthen Students' Religious Character
Authors: Setyawan Bagus Wahyu , Ulya Chafit , Hidayah Sa'adatun Nuril , Tawandorloh Ku-Ares
Published: June 2023

Religious character is one of the important characteristics to be developed, especially for students in the era of globalization. In fact, in some educational institutions, there is no particular curriculum to support the purpose of this study to examine in depth the implementation of the Islamic Approach-based curriculum as a medium to strengthen the religious character of Islamic boarding school madrasah ibtidaiyah students. The samples in this study were taken from madrasah ibtidaiyah in Tulungagung and Ponorogo. This research is case study research with data sources in the form of learning processes and informants consisting of students and teachers. Data were collected by observation and in-depth interviews with teachers, ustaz/ustazah, and students. The sample in this study consisted of 5 teachers and 20 students in each school. The results showed that there is a curriculum to develop religious character, discipline, and responsibility. The curriculum in each madrasah ibtidaiyah Boarding School is implemented in programs, both curricular and extracurricular. The integration of the national curriculum with the hidden curriculum in each institution makes the character education process maximized. Implemented programs such as praying before starting learning, saying greetings, and asking for ridho to the teacher/ustaz for religious character development. The habit of arriving on time, cultivating queuing, and utilizing free time to strengthen student discipline. For the development of responsibility, there is a picket program and a reward and punishment system. In addition, there is good coordination between teachers, ustaz, dormitory caregivers, and the foundation in determining effective programs in order to develop student character.
Integrating ICT to Improve Students' Achievement in Thematic Learning Islamic Education in the Indonesian School in Bangkok
Authors: Qomariah Nurul , Murtiyasa Budi , Shidiq Galih Albarra
Published: June 2023

This research aimed to identify how technology helped students develop their achievement by applying ICT-based learning media in thematic learning of Islamic Education at the Indonesian School in Bangkok. One of the important issues in elementary school is the need for more materials and resources for teaching and learning. Currently, technology is providing a better solution to solve the problem. In many cases, technology in education can improve students' knowledge and open their minds. This study used a qualitative method with a phenomenological approach of collecting data analysis consisting of interviews, documentation, and observation. The findings of this study explored the roles of students when they learned a technology by applying ICT-based learning media, which improves students’ motivation and inspire them to learn and provides a better understanding of learning in the classroom. However, these findings suggested that future studies could focus more on students' learning processes and teachers' abilities related to 21st-century skills.
Судьба русской культуры в интерпретации С.Н. Булгакова
Authors: Ковалева М.В. , Орлова Е.М.
Published: June 2023

Историческая и культурная ситуация начала ХХ века характеризуется сверхуплотненностью событий, радикальной переорганизацией социальной и духовной жизни, кризисом официального православного сознания. Именно в этих условиях складывается интерес к культурной проблематике и в центр отечественных гуманитарных исследований ставятся проблемы соотношения человека и культуры, соотношения духа и реальности. Плодотворным моментом в рассуждениях русских философов является анализ культурного кризиса в сложнейшем переплетении с экзистенциальным самоощущением человека. Но самое главное, русскими философами намечается важнейшая проблема понимания сущности культурного кризиса как момента переоценки ценностей, углубленного самопознания с учетом исторического опыта, в чем заложен исток последующих культурных преобразований.
Мошенничество с использованием электронных средств платежа: современные способы совершения
Authors: Анисимов А.А.
Published: June 2023

В статье анализируются способы совершения такого преступления, как мошенничество с использованием электронных средств платежа. Рассматриваются наиболее типичные ситуации, когда потерпевший невольно сам способствует совершению таких преступлений; рассказывается о технических способах собирания информации о пин-кодах банковских карт, что предшествует совершению мошенничества.
Подземное скважинное выщелачивание урановой руды на месторождениях
Authors: Абызбаев М.А.
Published: June 2023

В статье анализируется разведка и освоение урана с помощью выщелачиванием Показаны поэтапные работы при добыче и разработке полезного ископаемого от разведки до обогащения. Показаны требования для скважин при работе разработке рудных массиовов.
Вопросы проектирования и разработки модуля расширения штатного функционала библиотечной системы ИРБИС64
Authors: Ефимов Е.М , Васева Е.С.
Published: June 2023

Рассмотрены технологии проектирования и разработки сервиса расширения штатного функционала библиотечной системы ИРБИС64. Предложенный сервис позволяет осуществлять выгрузку данных из библиотечной системы в личный кабинет студента. Для организации взаимодействия серверного и клиентского приложения используется технологии Rest API. Для разработки программного решения используется язык программирования Python, фреймворки Flask и PythonIrbis. Материалы статьи могут служить практическими рекомендациями для проектирования и разработки подобных сервисов.
Ethnic identity of the student youth of the Republic of Bashkortostan: A sociological analysis
Authors:   Ufa University of Science and Technology, Gayfullin Andrey Yu.
Published: June 2023

The article is devoted to the study of the ethnic identity of the student youth of the Republic of Bashkortostan. The purpose of the study is to identify the features of ethnic identity among modern students of the Republic of Bashkortostan. The empirical material of the study is based on the results of the sociological survey of students conducted in 2022 by the Russian Society of Sociologists in different regions of Russia, including the Republic of Bashkortostan. The ethnic demographic features of the Republic of Bashkortostan are determined and the polyethnic nature of interethnic relations in the region is established. The manifestation of the affective aspect and the cognitive aspect of ethnic identity in the student youth of the Republic of Bashkortostan are considered. According to the results of the study, it was revealed how the student youth of the Republic of Bashkortostan determines their ethnic identity, how much the nationality of the mother and father affects the ethnic identity of the student youth of the Republic of Bashkortostan. The article analyzes how the structure of the student youth of the Republic of Bashkortostan by nationality, established by the results of self-identification of youth in a sociological survey, differs from the results of the All-Russian Population Census of 2020 with data on the national composition of the population of the Republic of Bashkortostan as a whole. The level of tolerance of students to the representatives of other nationalities was established, and the influence of the nationality factor on the communication of young people with other people was determined. The linguistic and confessional aspects of the studied issue are partially touched upon as ethnic differentiating signs of the cognitive aspect of ethnic identity. The positive ethnic identity of the student youth of the Republic of Bashkortostan was revealed as the dominant type. It is established that the student youth of the Republic of Bashkortostan demonstrates a high level of tolerance to representatives of other nationalities and does not consider the factor of nationality as a determining factor when choosing preferences in interpersonal communication.
Management of the organizational culture of a modern military team development
Authors:   Saratov Military Order of Zhukov Red Banner Institute of the National Guard Troops, Boldyrev Alexei N.
Published: June 2023

The article presents the analysis of theoretical approaches to the essence of managing the development of organizational culture of a modern military team. Military organizational culture is revealed as a complex of cultural values, norms, beliefs of military personnel, a managerial factor of transformation of professional changes in the modern military team. The specifics of the subject (military administration) and the object (members of the military collective) of management are substantiated, the integrated approach of the essential characteristics of the process of managing the development of the organizational culture of the military collective is revealed. As a result of the analysis of the sociological survey data, the characteristics of this phenomenon are clarified as a purposeful organizational, project, controlling activity of the military administration to ensure the reproduction of military organizational culture, the achievement of its stabilization, as well as progressive development. It is proved that the management of the development of the organizational culture of the military collective presupposes the achievement of a targeted qualitative renewal of the external symbols of the military collective, as well as the prevailing values, needs, ideals, traditions, norms of behavior of military actors. Management design of innovative norms, values, principles of interaction of military personnel is designed to allow not only to form an initiative military actor of a leadership type, but also to provide prerequisites for the transition to an innovative organizational culture of military teams. It is proved that the management of the development of the organizational culture of the military collective has several forms of manifestation: 1) as a dual complex within the framework of the general management system of a military organization; 2) as a mechanism aimed at, on the one hand, at ensuring the stabilization of organizational culture and, on the other hand, at its expanded reproduction; 3) as a subsystem of social management (federal, regional, internal-military-organizational; 4) as a management process itself. In a generalized context, the management of the development of organizational culture is a component of the overall system of integrated targeted management of a military unit as a whole, which determines, among other things, the optimization of its organizational culture. Within the framework of this management, management subsystems can be distinguished in the form of separate socio-cultural projects. Educational activity with this approach should be considered as a means to ensure the achievement of the development of the organizational culture of the military unit.
On the issue of digital socialization
Authors:   Saratov State University, Romanovskaya Olga A.
Published: June 2023

The article presents the reflection on the digital socialization. It is noted that the dynamics of actor socialization in the conditions of digitalization is due to information «challenges» that form a conscious desire to master social experience through online contexts, regardless the social actors` age. The multidimensionality of scientific research in the context of socially significant projects, such as, the Gutenberg Project, successfully implemented by Michael Hart; the project of the Columbia Center for Oral History (CCOH), containing an Archive of oral history, numbering more than 12,000 interviews and documentary artifacts; the project of the Russian Foundation «Oral History», which collects and makes available to society conversations on science, culture and everyday life of the twentieth century. The description of the most productive project, according to the author, «Why We Post» («Why We Post in Social Networks»), implemented by the team of anthropologists led by Daniel Miller (the researchers from London University College conducted field work in eight countries of the world for fifteen months and studied how social media works) is presented. The conclusion is substantiated that it is necessary to conduct field studies of the Network based on the intellectual tradition of studying both sociality and communication, which is an obvious basis for studying social networks and digital socialization, which forms identities through the use of the Internet.
Political discourse of health and ideological attitudes of Russian citizens
Authors:   National Medical Research Center for Therapy and Preventive Medicine, Suvorov Valeriy V.
Published: June 2023

Health is declared by citizens as one of the most important values, which makes it possible to address this topic within the framework of political discourse in order to achieve political goals. At the same time, the study of the manifestation and impact of the political discourse of health on the attitude of individual citizens and social groups to the sphere of health remains an understudied area of political science. A healthy lifestyle and health literacy were not included in the list of traditional values, although the topics of “health of the nation” and “health of citizens” are widely represented in public and political discourse. Political discourse, with the right emphasis, can have an impact on citizens’ attitudes towards health. It is possible to reveal this potential by determining the worldview features of the multicultural, socially differentiated population of Russia and taking them into account in the framework of political discourse and social policy. As the main methodology for studying the impact of various information channels, in which political discourse is presented, on worldview attitudes in relation to health, the concept of the sociocultural code of the health sector can be used, which opens up the possibility of developing ways for effective interaction with citizens, including the presentation of information by government officials and placement of accents, aimed at correcting the attitude of the population to their health.
Salud mental de niños, niñas y adolescentes argentinos, y pandemia por COVID-19: factores de riesgo y lecciones aprendidas
Authors: López Mariana Beatriz , Drivet Leandro
Published: June 2023

Objetivos. En el contexto general de la pandemia por COVID-19, este estudio tuvo como objetivos realizar un tamizaje de trastornos de salud mental en población de niños, niñas y adolescentes argentinos, y analizar los condicionantes socio-ambientales del desarrollo de estos problemas. Método. Se evaluaron 498 niños, niñas y adolescentes (NNyA) a través de informe colateral de sus padres o adultos a cargo. Para el tamizaje de trastornos de salud mental se utilizó la Strenght and Difficulties Scale (SDQ). Se evaluaron las situaciones familiares, sociales y educativas de los NNyA durante la pandemia por COVID-19 y se analizó su efecto en el desarrollo de trastornos de salud mental a través de un modelo de regresión lineal múltiple. Resultados. El 22.3% de los NNyA evaluados obtuvo puntuaciones anormales (> P 90) en la escala global de Dificultades del SDQ. Los síntomas emocionales fueron los más prevalentes. El impacto de la pandemia en la vida familiar, la cantidad de amigos íntimos que tenían los NNyA y su desempeño escolar explicaron el 28.4% de la varianza en la escala global de Dificultades. Conclusiones. Los problemas de salud mental infanto-juveniles adquieren centralidad en el contexto de pandemia y post-pandemia. Para su abordaje parece fundamental brindar a las familias más afectadas herramientas de contención social y económica que les permitan reorganizarse, reducir al mínimo las situaciones de aislamiento de los NNyA, y volver la mirada sobre la calidad educativa.
Prognosis in patients with cardiorenal syndrome depending on the clinical form of atrial fibrillation
Authors: Polyanskaya E. A.
Published: June 2023

Background. Atrial fibrillation (AF) is the most common stable arrhythmia in the population. The interaction of AF and cardiorenal syndrome is poorly understood, despite the fact that the proportion of such patients with combined heart and kidney damage reaches 60% among people with chronic heart failure (CHF). Data on the long-term prognosis in patients with cardiorenal syndrome depending on the form of AF is not enough.

Objective. To assess the prognosis in patients with cardiorenal syndrome depending on the clinical form of AF.

Design and methods. 126 patients with verified cardiorenal syndrome and various forms of AF were included. An observational study was performed with the fixation of hospitalizations for CHF and other cardiovascular events, including deaths.

Results. The rate of onset of the first end point is higher in patients with permanent AF (8.5 [3.0; 18.5] months and 15.0 [5.0; 24.0] months, p < 0.001). Analysis of survival curves shows a worse prognosis in patients with permanent AF.

Conclusion. In patients with cardiorenal syndrome in combination with AF, its clinical form has a significant impact on the long-term prognosis. Permanent AF, to a greater extent than paroxysmal/persistent AF, in conditions of cardiorenal syndrome is associated with faster and more frequent development of new cardiovascular events, including hospitalizations for decompensated CHF and deaths.
Role of 11C-choline PET/CT in parathyroid adenomas’ localization in patients with primary hyperparathyroidism
Authors: Pogosian K. A. , Karonova T. L. , Ryzhkova D. V. , Yanevskaya L. G. , Tsoy U. A. , Yudina O. V. , Ivanikha E. V. , Grineva E. N.
Published: June 2023

Background. Topical diagnosis of primary hyperparathyroidism (PHPT) remains an urgent problem due to the high incidence of persistence and recurrence after surgical treatment. At the preoperative stage, a search for the parathyroid hormone hyperproduction source is performed using instrumental methods: ultrasound, scintigraphy of the parathyroid glands (PTG) and multislice computed tomography (MSCT). The cause of PHPT persistence and recurrence after parathyroidectomy may be the multiple nature of PTG lesions or their ectopic location. Additional methods of visualization of PTG adenomas can be used to improve diagnosis (PET/CT).

Objective. To compare the sensitivity and specificity of PET/CT with 11C-choline with the traditional visualization techniques.

Design and methods. 16 PHPT patients were analyzed. All patients underwent US, subtraction scintigraphy with 99mTc-technetril/99mTc-pertechnitate and CT were performed in 12 and 16 patients, respectively. 11C-choline PET/CT was used for all patients. Imaging results’ coincidence of two methods were labeled as the true one.

Results. The sensitivity of PET/CT with 11C-choline was 94 %, CT, subtraction scintigraphy with 99mTc-technetril/99mTc-pertechnitate and US — 75 %, 69 % and 63 %, respectively. The specificity of PET/CT with 11C-choline, CT, scintigraphy with 99mTc-technetril/99mTc-pertechnitate, and US was 100 %, 84 %, 76 %, and 68 %, respectively.

Conclusion. PET/CT with 11C-choline demonstrated best sensitivity and specificity among all methods and can become an alternative in PHPT diagnostics in case of negative or inconvclusive results of previous visualization.
Vitamin D metabolism parameters in hospitalized COVID-19 patients
Authors: Mikhailova A. A. , Golovatyuk K. A. , Lagutina D. I. , Chernikova A. T. , Vasilieva E. Yu. , Bykova E. S. , Karonova T.  L.
Published: June 2023

Background. Recently, clinical benefits among COVID-19 patients, received vitamin D were demonstrated. Features of vitamin D metabolism in the acute period of COVID-19 remain unclear.

Objective. To assess the level of 25(OH)D and 1,25(OH)2D in hospitalized COVID-19 patients and cholecalciferol effect on the vitamin D metabolites dynamic.

Materials and methods. Group 1 (n = 22) patients received cholecalciferol bolus therapy at a total dose of 100,000 IU. Group 2 patients (n = 22) did not receive cholecalciferol supplementation. Serum 25(OH)D and 1,25(OH)2D levels were estimated for each group on the first and the ninth day of hospitalization.

Results. On the ninth day of hospitalization 25(OH)D serum level demonstrated the 45.8 % rise in the Group 1, while in the Group 2 there was a decrease in the 25(OH)D level by 17.9%. At the same time, dynamic evaluation of the 1.25(OH)2D level did not show any differences between the groups, while pairwise comparison on the first and on the ninth days of hospitalization revealed an increase in the active metabolite concentration (p < 0.001) in both groups.

Conclusion. Such vitamin D metabolism parameters in the acute period of COVID-19 may be associated with a 1α-hydroxylase activity alteration. Thus, 1.25(OH)2D serum level increase regardless of vitamin D status during the hospitalization could be explained by the COVID-19 course or concomitant corticosteroid medication.
Identifying quality gaps in tourism for people with disabilities: Importance-Performance Analysis (IPA)
Authors: Skalska Teresa
Published: June 2023

The aim of the article is to assess the significance (importance) and level of inconvenience of selected attributes of tourist services provided at particular stages of the supply chain in tourism (information, accommodation, transport, organization and intermediation) in relation to people with various types and degrees of disability. The survey conducted among the disabled helped to identify quality gaps in the provision of tourism services, taking into account their complementarity and accessibility at every stage of delivery. The method of Importance-Performance Analysis (IPA) and basic measures of descriptive statistics were used to analyze empirical data. The study will help to indicate to what extent the tourist experience of a disabled person and the type of disability affect the assessment of the significance (importance) and inconvenience of selected attributes of tourist services. The results of the research can be used by entrepreneurs to analyze the quality and reliability of services provided by their partners and the behavior and needs of the disabled in tourism. They will also be useful for local and regional authorities responsible for ensuring the competitiveness and inclusiveness of tourism regions.
Influence of Sucrose, Boric Acid and Calcium Chloride on in vitro Pollen Germination and Tube Elongation of Alfalfa
Authors: Shi Ruru , Shi Fengling , Wang Shushuan
Published: June 2023

Background: In a genetic breeding program, understanding the viability of pollen germination and pollen tube growth is an essential factor for artificial hybridization. Currently, little is known about the influence of sucrose, boric acid concentrations and calcium chloride on pollen viability in alfalfa. This study is valuable for providing information about pollen germination requirements to support further improvement of artificial pollination and breeding programs in alfalfa. Methods: The single-factor experimental and an orthogonal design method (L16 [4]3) was used to compare the effectiveness of key factors (e.g., concentrations of sucrose, boric acid and calcium chloride) to determine the pollen vigor of Medicago varia Martin. ‘Caoyuan No.1’and M. ruthenica L. Trautv. ‘zhilixing’ and to optimize the culture medium for in vitro pollen germination. Four different varieties were chosen to compare the diurnal variation of pollen vigor. Result: The four factors that influenced pollen germination in Medicago varia Martin. ‘Caoyuan No.1’and M. ruthenica L. Trautv. ‘zhilixing’ in order of significance are as follows: sucrose greater than H3BO3 greater than CaCl2. These variables influenced pollen tube growth in the following order: sucrose greater than H3BO3 greater than CaCl2. The optimal culture medium for promoting pollen vigor of Medicago varia Martin.‘Caoyuan No.1’ was 10% sucrose, 300 mon/L H3BO3 and 100 mon/L CaCl2; that of M. ruthenica L. Trautv. ‘zhilixing’ was 10% sucrose, 200 mon/L H3BO3 and 50 mon/L CaCl2. Among several species of alfalfa, ‘Caoyuan No.1’ shows the highest pollen vigor and the daily pollen activity curves of all varieties showed a single peak type.
Yaşlılarda Geriatrik Sendromlardan Biri Olan Kırılganlık ve Hemşirelik Bakımı
Authors: KALYONCUO Servet
Published: June 2023

Yaşlılık dönemi fizyolojik anlamda bir dizi değişikliğin meydana geldiği normal bir yaşam dönemidir. Yaşlılığa özgü pek çok sağlık sorunu bulunmakla birlikte yaşlanma sürecine bağlı gelişen en önemli sorunlarından biri kırılganlıktır. Yaşın ilerlemesiyle birlikte ortaya çıkan kırılganlık, organlarda fizyolojik rezervlerin azaldığı, bilişsel yeteneklerin bozulduğu, azalan güç ve savunmasızlıkla karakterize bir sendromdur. Kırılganlık, karmaşık bir sendromdur ve çok boyutlu bir yapıya sahiptir. Bu çok boyutlu sendrom ile baş etmede hemşireler yaşlı bireylere uygun egzersiz, doğru/dengeli beslenme programları, ortam düzenlemeleri, kişisel hijyen ve inkontinans gibi özel konulardan oluşan bireye özgü ve bütüncül müdahaleler ile hemşirelik bakımını sürdürmelidirler. Bu derleme ile yaşlılık döneminde önemli bir sorun olan kırılganlık ve hemşirelik bakımı hakkında bir çerçeve oluşturulması amaçlanmıştır.
La forêt et la faune de Côte d’Ivoire dans une situation alarmante – Synthèse des résultats de l’Inventaire forestier et faunique national
Authors: CUNY Pascal , PLANCHERON Françoise , BIO Abraham , KOUAKOU Elvis , MORNEAU François
Published: June 2023

La Côte d’Ivoire a engagé début 2019 un inventaire national de ses forêts et de sa faune, accompagné par des enquêtes socio-économiques auprès des agriculteurs. Cet inventaire, déployé sur l’ensemble du territoire, fournit une grande quantité d’informations. Il montre que l’état des forêts et de la faune est fortement dégradé et que les cultures industrielles (cacaoyer, hévéa, palmier à huile dans le sud, anacardier et coton dans le centre et le nord) sont devenues dominantes. La superficie de la forêt en Côte d’Ivoire est estimée en 2020 à 2,97 millions d’hectares, soit 9,2 % de la surface totale du territoire, dont 2,88 millions d’hectares de forêt (dite) naturelle et un peu plus de 92 000 ha de reboisement. Le taux de déforestation moyen annuel depuis 1986 est de 2,8 % (superficie de la forêt en 1986 de 7,85 millions d’hectares). La superficie de la forêt dans les forêts étatiques, dites forêts classées, n’est plus que de 13,3 % alors que la création des forêts classées dans les années 1970 avait pour objectif la préservation et la gestion durable des forêts. La raréfaction, voire la disparition, des essences commerciales ne permet plus de mettre en œuvre une exploitation forestière respectant les critères de gestion durable. Les aires protégées (parcs nationaux, réserves) ne contiennent plus que 32,2 % de forêt. En outre, des transects d’observation de la faune déployés sur tout le territoire ont permis de montrer que la faune commune (aulacode, guib harnaché, lièvre, etc.) est encore bien présente. En revanche, les grands mammifères (antilopes, éléphants, singes) sont cantonnés dans quelques aires protégées et forêts classées avec des tailles de population souvent critiques. Enfin, l’analyse socio-économique montre que les forêts classées sont occupées par une population humaine composée à 50 % d’allogènes, à 28 % d’autochtones et à 22 % d’allochtones : le cacao occupe la plus grande partie des cultures installées majoritairement par les allogènes. Dans le domaine rural, ce sont surtout les autochtones (76 %) qui s’investissent dans l’agriculture (principalement l’anacarde), suivis des allogènes (13 %) et des allochtones (11 %). L’état des écosystèmes forestiers et de leur faune est alarmant, mais des mesures fortes prises rapidement pourraient permettre d’améliorer cette situation au moins dans les secteurs les mieux préservés. La poursuite de campagnes d’inventaire régulières sera un outil essentiel pour mesurer l’impact de ces décisions.
Contribution à l’étude de la variabilité chez le cèdre de l’Atlas au Maroc
Authors: EL BAKKALI Nezha
Published: June 2023

Le cèdre de l'Atlas (Cedrus atlantica (Endl.) G. Manetti ex Carrière) est une espèce endémique des montagnes du Maroc et de l’Algérie. Il constitue une ressource vitale pour les populations et d’intérêt bioécologique et socio-économique considérable. Cette ressource naturelle est malheureusement menacée par plusieurs facteurs de dépérissement et l’évolution rapide du climat vers la sécheresse, ce qui le pousse à modifier sa morphologie pour acquérir des caractères d’adaptation. Dans cette thèse, l’identification des traits morphologiques et anatomiques adaptatifs de Cedrus atlantica au Maroc est abordée via :

L'évaluation de l’adaptabilité écologique et la microévolution des populations naturelles de atlantica basée sur l'analyse des caractères morphologiques et anatomiques des aiguilles.

L’étude de certains caractères adaptatifs des aiguilles des populations du cèdre dans le Moyen Atlas central présentant des conditions environnementales et des niveaux de diversité génétiques différents.

L’étude morphométrique effectuée sur des caractères morpho-anatomiques de l'aiguille dans des populations naturelles dans les montagnes du Moyen et du Haut Atlas au Maroc.

Les résultats de l’évaluation de l’influence de la géographie sur la morphologie et l’anatomie des aiguilles du C. atlantica montrent l’existence d’une adaptation de la structure des aiguilles à la position géographique et aux conditions climatiques des populations. De même, les populations du Moyen Atlas central présentant des conditions environnementales et des niveaux de diversité génétiques différents ont montré que les adaptations morpho-anatomiques des aiguilles sont en harmonie avec leur spécificité génétique révélée précédemment. Enfin, l’étude comparative de la variabilité morpho-anatomique des aiguilles des populations du Moyen et du Haut Atlas a confirmé l'existence de deux écotypes distincts génétiquement de C. atlantica, géographiquement distants dans les montagnes de l'Atlas. En conséquence, cela a permis de cerner l'écotype en conférant à cette espèce une place de choix dans les projets de revalorisation des populations méditerranéennes, en particulier sur les zones semi-arides. Ces résultats montrent que les traits morpho-anatomiques des aiguilles permettent l’évaluation de la diversité intra- et inter-population chez le cèdre de l’Atlas. De plus, ils ont une importance capitale dans les programmes de sélection ainsi que dans les études relatives à la microévolution du genre Cedrus au Maroc.
SENYAWA KIMIA AKTIF BUAH NIPAH (Nypa fruticans Wurmb) BERDASARKAN 3 TINGKAT KEMATANGAN BUAH
Authors: Suryanizak Elmalia Rinten , Radam Rosidah , Yuniarti Yuniarti
Published: June 2023

The nipah plant (Nypa fruticans Wurmb) is a type of betel nut tribe that lives in brackish water marsh areas. The spread of nipah in South Kalimantan covers areas in Banjar Regency, Tanah Laut Regency, Tanah Bumbu Regency and Pulau Laut Regency. Nipah fruit has antibacterial content and is useful as a food source that can be used as a diet food. This study aims to analyze the content of akif chemical compounds, namely flavonoids, tannins, alkaloids, steroids and triterpenoids in nipah fruit (Nypa fruticans Wurmb) at 3 levels of fruit maturity. Phytochemical tests are carried out to determine the class of compounds contained in nipah fruit. This research began with the manufacture of simplicia first then a phytochemical test was carried out using a color test, showing positive results that the nipah fruit contains active chemical compounds alkaloids and tanninsTumbuhan nipah (Nypa fruticans Wurmb) merupakan jenis palem atau suku pinang-pinangan yang hidup di daerah rawa berair payau. Penyebaran nipah di Kalimantan Selatan meliputi wilayah di Kabupaten Banjar, Kabupaten Tanah Laut, Kabupaten Tanah Bumbu dan Kabupaten Pulau Laut. Buah nipah memiliki kandungan antibakteri dan bermanfaat sebagai sumber pangan yang dapat dijadikan sebagai makanan diet. Penelitian ini bertujuan menganalisis kandungan senyawa kimia akif yaitu flavonoid, tanin, alkaloid, steroid dan triterpenoid pada buah nipah (Nypa fruticans Wurmb) pada 3 tingkat kematangan buah. Uji fitokimia dilakukan untuk mengetahui golongan senyawa yang terdapat dalam buah nipah. Penelitian ini diawali dengan pembuatan simplisia terlebih dahulu kemudian dilakukan uji fitokimia menggunakan tes uji warna, menunjukkan hasil positif bahwa buah nipah mengandung senyawa kimia aktif alkaloid dan tanin.