bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Unexpected Entry to a Novel Carbocyclic Tricyclic System.
Authors: MURPHY W. S. , CULHANE A. , JUO R.‐R.
Published: May 2016

The bis(cyclopropyl) ketone (I) undergoes rapid Lewis acid catalyzed rearrangement to the highly symmetrical dibenzotricyclic system (II).
ChemInform Abstract: Synthesis of 4‐ and 5‐Substituted 10‐Oxatricyclo(5.2.1.02,6)decadienones. Functionalization of the Cycloadduct of Furan and Cyclopentene‐1,4‐dione.
Authors: HOUWEN‐CLAASSEN A. A. M. , KLUNDER A. J. H. , KOOY M. G. , STEFFANN J. , ZWANENBURG B.
Published: May 2016

The ethylation/tosylmethylation product (V) of the furan‐cyclopentenedione adduct (I) can be converted to oxatricyclodecadiones such as (IX), (XI) or (XII) via intermediates such as (VIIa) + (VIII) or (VIIb).
ChemInform Abstract: Synthesis of Polynitro‐2,6‐dioxabicyclo(3.3.0)octanes.
Authors: ARCHIBALD T. G. , BAUM K.
Published: May 2016

The known dianhydromannitol ditosylate (I) undergoes SN2 reaction with sodium azide (II) to yield the diazido compound (III).
ChemInform Abstract: Thermal Rearrangement of Dimethylaminomethylenethiaspirononenes and Thiaspirodecenes.
Authors: COTELLE P. , BARBRY D. , HASIAK B. , COUTURIER D.
Published: May 2016

The bicyclic ammonium salts (I) react with sodium amide in liquid ammonia to give the spirocyclic amines (II), together with the unsaturated amines (III).
ChemInform Abstract: Electrophilic Substitution in Indoles. Part 17. The Cyclization of (Dimethoxyphenylacetyl)tryptamines to Spiropentacyclic Indole Derivatives.
Authors: BISWAS K. M. , JACKSON A. H.
Published: May 2016

With a view to mechanistic aspects of the indole chemistry and to the synthesis of pentacyclic indole alkaloids, the intramolecular cyclization of the tryptamine (I) containing a suitable side chain is investigated.
ChemInform Abstract: The Chemistry of N‐Substituted Benzotriazoles. Part 22. Transformations of 1‐(Trimethylsilylmethyl)benzotriazole.
Authors: KATRITZKY A. R. , LAM J. N.
Published: May 2016

The title compound (III) undergoes acylative and fluoride‐catalyzed desilylations with carbonyl compounds to give products of type (V) and (VIII), respectively.
ChemInform Abstract: Activated Nitriles in Heterocyclic Synthesis: Novel Synthesis of Substituted Coumarin Derivatives.
Authors: ELGEMEIE G. H.
Published: May 2016

The coumarin derivatives (IV), (VII), (VIII), and (X) are synthesized as shown in the reaction scheme.
ChemInform Abstract: Synthesis in the Phenanthridine Series. Part 2. Preparation of Novel Methyl‐ and Ethyl ω‐(6‐Phenanthridinyl)alkanoates.
Authors: LION C. , BOUKOU‐POBA J. P. , CHARVY C.
Published: May 2016

The methodology described in the preceding communication is also applied to the synthesis of the title compounds of type (IV).
ChemInform Abstract: Carbon‐Nitrogen Bond Formation in Cyclizations by Deoxygenation, Thermolysis, or Photolysis of Phenylimidazo(1,2‐a)pyridine Systems: Access to Pyrido(1′,2′:1,2)imidazo(4,5‐b)indoles.
Authors: TEULADE J. C. , GUEIFFIER A. , VIOLS H. , CHAPAT J.‐P. , GRASSY G. , PERLY B. , DAUPHIN G.
Published: May 2016

In connection with studies of the reactivity of nitrogen bridgehead azaindolizines, the nitro derivative (I) is treated with excess P(OEt)3.
ChemInform Abstract: 1,3‐Pyridodioxane Derivatives. Part 3. 1,3‐Dioxino(4,5‐c)pyridinium Ylides and 1,3‐Dioxino(4,5‐g)indolizines: Synthesis and Properties.
Authors: ARUSTAMOVA I. S. , KUL'NEVICH V. G.
Published: May 2016

Quaternization of the pyridodioxanes (I) yields the pyridinium bromides (III).
ChemInform Abstract: Imidazo(1,2‐b)pyridazines. Part 7. Syntheses and Central Nervous System Activities of Some 3‐Alkoxy‐6‐benzyloxy(and methoxybenzyloxy)‐2‐phenyl(substituted phenyl or pyridinyl)imidazo(1,2‐b)pyridazines.
Authors: BARLIN G. B. , DAVIES L. P. , NGU M. M. L.
Published: May 2016

The title compounds (I) and (II) are synthesized according to the methods delineated in the preceding abstract; the aminosubstituted analogues are obtained from the respective nitro compounds by reduction.
ChemInform Abstract: Imidazo(1,2‐b)pyridazines. Part 8. Syntheses and Central Nervous System Activities of Some 6‐Benzylamino(and methoxybenzylamino)‐3‐methoxy‐2‐phenyl(substituted phenyl or pyridinyl)imidazo(1,2‐b)pyridazines.
Authors: BARLIN G. B. , DAVIES L. P. , NGU M. M. L.
Published: May 2016

A variety of title compounds, e.g. (IV), are synthesized by a method corresponding to that shown in the scheme for (IVa).
ChemInform Abstract: Unexpected Formation of a 11H‐Pyrido(2,1‐b)quinazolin‐11‐one Derivative from 5,11‐Dihydro‐6H‐pyrido(2,3‐b)‐1,4‐benzodiazepin‐6‐one.
Authors: BUDESINSKY M. , SYMERSKY J. , PODLAHA J. , PODLAHOVA J. , POLIVKA Z. , PROTIVA M.
Published: May 2016

Treatment of the benzodiazepinone (I) with chloroacetyl chloride (II), followed by reaction of the crude product with N‐methylpiperazine (III), affords an unexpected by‐product, i.e. the quinazolinone (IV).
ChemInform Abstract: Synthesis of Thieno(2,3‐d)pyrimidine Derivatives and Their Antifungal Activities.
Authors: KONNO S. , TSUNODA M. , WATANABE R. , YAMANAKA H. , FUJITA F. , OHTSUKA N. , ASANO S.
Published: May 2016

The aminothiophenecarboxamides (I) are converted to the chlorothienopyrimidines (VI) which react with nucleophiles (VII) to yield the substituted thienopyrimidines (VIII).
ChemInform Abstract: Synthesis of Perchlorates of Pyrylo(2,3‐c)‐ and Thiopyrylo(2,3‐c)‐5,6,7,8‐tetrahydroazepin‐9‐ones.
Authors: KLIMENKO S. K. , IVANOVA N. N. , SOROKIN N. N.
Published: May 2016

Nitrosation of the thiopyrylium (Ia) or pyrylium (Ib) perchlorates according to the standard procedure affords the oximes (III), which are converted to the title compounds (IV) on gentle heating in HClO4.
ChemInform Abstract: The Quantitative Electrophilic Reactivity of Annulenes. Part 5. Trithiadiazepine, Its 6‐Bromo‐ and 6‐Nitro Derivatives, and Trithiatriazepine.
Authors: LAWS A. P. , TAYLOR R.
Published: May 2016

Quantitative electrophilic reactivities of the title compounds (I) and (II) are determined via acid‐catalyzed hydrogen exchange (protiodetritiation).
ChemInform Abstract: Synthesis and Mesomorphous Properties of 2‐(4‐Carboxyphenyl)‐5‐alkyl‐1,3,2‐dioxaborinanes and Their Cyano Derivatives.
Authors: BEZBORODOV V. S.
Published: May 2016

In comparison to their 1,3‐dioxane analogues, the compounds (III), (V) and (VII) display nematic phases at lower (ca.
ChemInform Abstract: Two Polymorphs of the Diazaphosphole Oxide C6H4(NH)2P(O)Ph.
Authors: BARENDT J. M. , BENT E. G. , HALTIWANGER R. C. , SQUIER C. A. , NORMAN A. D.
Published: May 2016

The polymorphous title compound (III) (space group Pnma, Z=4) forms in high yields as shown in the scheme, and in moderate yield (33%) from the reaction of the diamine (I) with PhP(OPh)2.
ChemInform Abstract: Desulfurization of Vicinal Bisphosphorothioates: A Novel Synthesis Route to Substituted Cyclic Pyrophosphates.
Authors: NOBLE N. J. , POTTER B. V. L.
Published: May 2016

1‐Phenylethane‐1,2‐diol (I) is coupled with the amidochlorophosphite (II) and 3‐hydroxypropionitrile (III) to give the bisphosphite (IV) which is sulfurized and then cleaved to yield the 1‐phenylethane‐1,2‐bisphosphorothioate (VII).
ChemInform Abstract: Synthesis and Characterization of Vanadium(V) and ‐(IV) Hydroxamate Complexes. X‐Ray Crystal Structures of Oxochlorobis(benzohydroxamato)vanadium(V) and Oxoisopropoxo(N,N′‐dihydroxy‐N,N′‐diisopropylheptanediamido)vanadium(V).
Authors: FISHER D. C. , BARCLAY‐PEET S. J. , BALFE C. A. , RAYMOND K. N.
Published: May 2016

Although hydroxamic acids have been used for many years in colorimetric analyses of vanadium, the full characterization of the complexes formed has not been accomplished.
ChemInform Abstract: Synthesis and Reactivity of Alkoxide‐Bridged Cobaltic Acetates.
Authors: SUMNER C. E. JUN. , STEINMETZ G. R.
Published: May 2016

The μ‐alkoxide complexes (III) (X‐ray analysis of (IIIc): space group C2/c; Z = 8) are synthesized by treatment of (I) with a primary alcohol (II) in refluxing acetonitrile.
ChemInform Abstract: Synthesis and Characterization of the Bis(1,3‐bis(methylthio)‐1,3‐propanedithionate) Complexes M(S2C3H(SCH3)2)2 (M: NiII, PdII, PtII).
Authors: SINGH H. B. , JACOBSON R. H. , HINKELMANN K. , SRDANOV G. , WUDL F.
Published: May 2016

The new title complexes (IV) are synthesized via a "one‐pot" procedure as demonstrated for the Ni derivative (IVa) (space group P1, Z=1).
ChemInform Abstract: Separation of Peptide Diastereomers by Reversed‐Phase HPLC and Its Applications. Part 2. Gly‐L‐Phe‐OMe, a Useful Derivatization Reagent for Chiral Separation of N‐(Benzyloxycarbonyl)amino Acids by Reversed‐Phase High‐Performance Liquid Chromatography.
Authors: YAMADA T. , DEJIMA K. , SHIMAMURA M. , MIYAZAWA T. , KUWATA S.
Published: May 2016

Twenty‐two racemic N‐protected amino acids (Cbz‐AA) are coupled with the title reagent to give the tripeptides Cbz‐AA‐Gly‐L‐Phe‐OMe, containing the achiral spacer Gly between two chiral amino acids.
ChemInform Abstract: Radical Cyclization Reactions Leading to Doubly Branched Carbohydrates and 6‐ and 8‐Oxygenated 2,9‐Dioxabicyclo(4.3.0)nonane Derivatives.
Authors: FERRIER R. J. , PETERSEN P. M. , TAYLOR M. A.
Published: May 2016

The bromoethyl hexenopyranoside (I) reacts with methyl acrylate (II) in the presence of tri‐n‐butyltin hydride under addition and cyclization to yield the fused sugars (III) and (IV); the debromination product (V) is also observed.
ChemInform Abstract: Photophysical Studies of Luminarosine ‐ A New, Highly Fluorescent Ribonucleoside with Pteridine‐Like Betaine as the Aglycone.
Authors: SKALSKI B. , PASZYC S. , ADAMIAK R. W. , STEER R. P. , VERRALL R. E.
Published: May 2016

The solvent and pH dependence of the absorption and fluorescence spectra, fluorescence quantum yields and lifetimes, and fluorescence quenching behavior of tri‐O‐acetyl‐β‐luminarosine (Ia), β‐luminarosine itself (Ib), the α‐anomer (II), and the aglycone luminarine (III) are reported.
ChemInform Abstract: Effect of Oxygen Stoichiometry on the Superconductivity of Pb2Sr2Y1‐xCaxCu3O8+δ.
Authors: GYORGY E. M. , O'BRYAN H. M. , GALLAGHER P. K.
Published: May 2016

Ceramic samples of the title compound with x = 0, 0.2, and 0.4 are prepared.
ChemInform Abstract: Morphological and Electrocatalytic Properties of Gold Deposits on NaY Zeolite.
Authors: ENEA O.
Published: May 2016

Porous, but electrically conductive, thin films of gold are electrochemically deposited onto NaY‐zeolite discs.
ChemInform Abstract: Indium(III)‐Hexacyanoferrate(III,II) as an Inorganic Material Analogous to Redox Polymers for Modification of Electrode Surfaces.
Authors: KULESZA P. J. , FASZYNSKA M.
Published: May 2016

The deposition of polynuclear In(III)‐hexacyanoferrate(III,II) films is performed by cycling the glassy carbon substrate between 0.85 and 0.0 V (vs.
ChemInform Abstract: Reaction Volumes of Excited‐State Processes: Formation and Complexation of the Pt2(P2O5H2)4‐ 4 Excited State.
Authors: HERMAN M. S. , GOODMAN J. L.
Published: May 2016

Photoacoustic calorimetry (PAC) is used to measure the reaction volume and enthalpy for the formation and complexation of the excited state of the title ion.
ChemInform Abstract: Anomalous Shielding and Hidden Partner Chemical Exchange in the 1H NMR Spectra of the Bisurethane Diazetidines, the 1,2‐Diaryl‐3,5‐dialkyl‐6,7‐dialkoxycarbonyl‐4‐oxo‐6,7‐diazabicyclo(3.2.0)hept‐2‐enes.
Authors: MACKAY D. , MCINTYRE D. D. , WIGLE I. D.
Published: May 2016

The bicyclic diazetidines (I) (known compounds; (Ia) studied in more detail; analogous with each one and both R: ‐CD3 are studied as well), (II) and (III) (syntheses are described) have trans‐pyramidal nitrogens.
ChemInform Abstract: Stereoselectivity of the Alkylation of the Dianion of Ethyl 2‐Hydroxy‐6‐methylcyclohexanecarboxylates: Control of Stereochemistry at Three Adjacent Stereogenic Centers.
Authors: FRATER G. , GUENTHER W. + , MUELLER U. +
Published: May 2016

Yeast reduction of the cyclohexanecarboxylate (±)‐(I) is both enantioselective and product‐specific yielding only one reduced stereoisomer (+)‐(II).
ChemInform Abstract: Stereo‐ and Regioselective Functionalization of the Double Bond of Diels‐Alder Adducts of Sulfonyl Dienophiles and Cyclic Dienes.
Authors: COSSU S. , DE LUCCHI O. , DILILLO F.
Published: May 2016

The double bond of Diels‐Alder cycloadducts such as (II) can be stereo‐ and regiospecifically functionalized in both ionic and radical reactions to provide products such as (I), (IV), or (X).
ChemInform Abstract: A New Tin(II) Chloride‐Silver(I) Acetate or ‐Lead(II) Bromide Reagent for the Addition of F‐Alkyl Iodides to Alkenes.
Authors: ISHIHARA T. , KUROBOSHI M.
Published: May 2016

The addition of the fluoroalkyl iodides (II) to the alkenes (I) or (IV) is mediated by tin dichloride in the presence of silver acetate or lead dibromide, producing the iodopolyfluoroalkenes (III) or (V).
ChemInform Abstract: The Michael Addition of Enamines to Propenamidines. A Convenient Synthesis of 2‐(β‐Amidinoethyl)cycloalkanones by Amidinoethylation Reaction.
Authors: FUKS R. , VAN DEN BRIL M.
Published: May 2016

Acrylonitrile (I) is converted to the nitrilium salt (IV) which reacts with the anilines (V), producing the propenamidines (VI).
ChemInform Abstract: Hydrophobic Control of Organic Stereochemistry. Changes of Regioselectivity in Diels‐Alder Reactions by Salt Effects.
Authors: CASETTA M. , COLONNA S. , MANFREDI A.
Published: May 2016

The regioselectivity of the Diels‐Alder reaction of naphthoquinones such as (I) with the cyclohexadiene (II) in H2O as solvent is influenced by the addition of different electrolytes.
ChemInform Abstract: Reaction of Ketene Alkyl Silyl Acetals with Acrylonitrile and 2‐Chloroacrylonitrile.
Authors: QUENDO A. , ROUSSEAU G.
Published: May 2016

When the title reaction between the ketene acetals (I) and the nitriles (II) is performed in tetrachloromethane in the presence of zinc bromide, (2 + 2)cycloaddition takes place to form the cyclobutanecarbonitriles (III).
ChemInform Abstract: Nickel(0)‐Catalyzed Cycloaddition of Ethoxyethyne with Carbon Dioxide to 4,5‐Diethoxy‐α‐pyrone.
Authors: TSUDA T. , KUNISADA K. , NAGAHAMA N. , MORIKAWA S. , SAEGUSA T.
Published: May 2016

The reaction of ethoxyethyne (I) with carbon dioxide (II) is performed in the presence of various nickel(0) phosphine catalysts to give the diethoxy‐α‐pyrone (III) and/or the triethoxybenzenes (IV) and (V).
ChemInform Abstract: Control of Product Distribution by Marcus Type Electron‐Transfer Rates for the Radical Pair Generated in Benzylic Ester Photochemistry.
Authors: DECOSTA D. P. , PINCOCK J. A.
Published: May 2016

Assuming that the ratio of the photoproducts (III) and (V) is determined by the rate ratio for the electron transfer and decarboxylation process of the in‐cage radical pair generated from (I), the rate of electron transfer kET is calculated.
ChemInform Abstract: Photosensitized cis/trans‐Isomerization of 1‐(1‐Propenyl)cycloalkenes.
Authors: INMAN W. D. , SANCHEZ K. A. J. , CHAIDEZ M. A. , PAULSON D. R.
Published: May 2016

The photosensitized cis/trans‐isomerization of the dienes (III) and (IV), (IX) and (X), or (XIV) and (XV), prepared as outlined in the reaction scheme, is studied in the presence of thirteen different sensitizers.
ChemInform Abstract: New Oxidizing Reagent: Peroxysulfonimidoyl Intermediate Generated from Sulfonimidoyl Chloride and Superoxide.
Authors: KIM Y. H. , YOON D. C.
Published: May 2016

Treatment of the sulfonimidoyl chloride (I) with potassium superoxide (II) in the presence of a crown ether generates the peroxysulfonimidoyl derivatives (III) and (IV) which are employed in situ in the oxidation of the sulfides (VI) to give the sulfoxides (VII) and in the epoxidation of the olefins (IX).
ChemInform Abstract: New General Processes of Homolytic Alkylation of Heteroaromatic Bases by t‐BuOOH or (t‐BuO)2 and Alkyl Iodides.
Authors: FONTANA F. , MINISCI F. , NOGUEIRA BARBOSA M. C. , VISMARA E.
Published: May 2016

Selective homolytic alkylation is observed in the presence of methyl radicals generated from Me3C‐OOH and (Me3C‐O)2.
ChemInform Abstract: Acylation of Hydroxy‐ and Mercaptocarboxylic Acid Esters Using the Carbodiimide/Acylation Catalyst Method.
Authors: RAO N. N. , ROTH H. J.
Published: May 2016

Acylation of (S)‐ethyl lactate (II) with various carboxylic acids, e.g. (I), yielding the corresponding esters (III), is performed in the presence of carbodiimide and pyridine base as the catalyst.
ChemInform Abstract: (2,3)Wittig Rearrangement on Carbohydrate Template. Novel Approach to Chiral Synthesis of 3‐Alkylmalic Acids.
Authors: KAKINUMA K. , LI H.‐Y.
Published: May 2016

The ketone (I) derived from a furanoside is reductively alkynylated with the lithium acetylide (II) to produce the alkynylfuranoside (III) which is hydrogenated or reduced and then etherified with the bromoacetate (IV), yielding selectively the Z‐ or E‐configurated alkenyl derivative (Va) or (Vb).
ChemInform Abstract: Bicycloprop‐2‐enyl (IV).
Authors: BILLUPS W. E. , HALEY M. M.
Published: May 2016

The last unknown (CH)6 isomer (IV) is prepared by doubly carbene addition to butadiene (I) and gas‐solid reaction of the resulting bicyclopropane (III).
ChemInform Abstract: The in‐Bicyclo(4.4.4)‐1‐tetradecyl Cation (VI): A Stable Substance with a Three‐Center, Two‐Electron C‐H‐C Bond.
Authors: MCMURRY J. E. , LECTKA T. , HODGE C. N.
Published: May 2016

Catalytic hydrogenation of the alkene (V) (H2, Pd‐C) yields the in,out‐bicyclo(4.4.4)tetradecane.
ChemInform Abstract: Imidolactones. Part 4. N‐(2‐Phenylethyl)hexahydroisochroman‐1‐imines.
Authors: MEISE W. , MIKA U.
Published: May 2016

Depending on the reaction conditions, coupling of the 2‐phenylethylamines (II) with the cis‐isochromanone (I) gives the cis‐ (III) or the trans‐2‐hydroxyethylcyclohexanecarboxamides (IV) as the main products.
ChemInform Abstract: Activation of Reducing Agents. Sodium Hydride‐Containing Complex Reducing Agents. Part 32. NiCRAL′s as Very Efficient Agents in Promoting Cross‐Coupling of Aryl Halides.
Authors: LOURAK M. , VANDERESSE R. , FORT Y. , CAUBERE P.
Published: May 2016

Forty‐seven coupling reactions between aryl bromides such as (I) and aryl chlorides such as (II) are carried out with the NiCRA‐bpy reagent.
ChemInform Abstract: Preference for anti‐1,4‐Elimination of Hydrochloric Acid Promoted by Base in Systems with Non‐Cyclic C(1)‐C(2) Bonds.
Authors: OELWEGARD M. + , AHLBERG P.
Published: May 2016

Treatment of the diastereomeric chloroethyldeuterioindenes (I) or (IV) with DABCO (1,4‐diazabicyclo(2.2.2)octane) results in 1,4‐elimination of HCl, producing the ethylideneindenes (I) and (III).
ChemInform Abstract: Diethylaminopropionamido(hydroxy)anthraquinones as Potential Anticancer Agents: Synthesis and Characterization.
Authors: ANTONELLO C. , URIARTE E. , PALUMBO M.
Published: May 2016

The 1‐amino‐4‐hydroxyanthraquinones (I) are coupled with 3‐chloropropionyl chloride (II), yielding the corresponding amides (III).
ChemInform Abstract: Synthesis of the Non‐K‐Region Arene Oxides and Tetrahydro Epoxides of Dibenz(a,h)anthracene.
Authors: PLATT K. L. , FRANK H. , OESCH F.
Published: May 2016

The title compounds (VIII) and (IX) are prepared starting from the ketone (III), for which an improved synthesis is described.
ChemInform Abstract: Synthesis and Structure of a New Chiral Oxaziridine from (3‐Oxo‐camphorsulfonyl)imine.
Authors: MELADINIS V. , HERRMANN R. , STEIGELMANN O. , MUELLER G. +
Published: May 2016

Oxidation of the camphor derivative (I) by magnesium monoperoxyphthalate affords the novel title compound (II) with an oxygen atom inserted in the cyclohexane moiety of (I).
ChemInform Abstract: Unsymmetrically Substituted Furoxans. Part 11. Methylfuroxancarbaldehydes.
Authors: FRUTTERO R. , FERRAROTTI B. , SERAFINO A. , DI STILO A. , GASCO A.
Published: May 2016

The structures of the title compounds (III) and (IV), their thermal equilibration and the kinetics of the conversion of (III) to (IV) are discussed.
ChemInform Abstract: Electrophilic Condensation of Silyl Ethers of Homopropargyl Alcohols with Aldehydes. Regioselective Synthesis of Dihydropyrans.
Authors: CHAN T.‐H. , ARYA P.
Published: May 2016

The homopropargylic alcohol (I) reacts with the aldehydes (II) in the presence of AlCl3 to give mixtures of the hydroxy enones (III) ‐ (V).
ChemInform Abstract: Synthesis of Pyrano(4,3‐b)indoles as Conformationally Restricted Analogues of the Serotonin Antagonist ICS 205‐930 and as Precursors to 2‐Vinylindoles.
Authors: MACOR J. E. , RYAN K. , NEWMAN M. E.
Published: May 2016

The ethyl indole‐3‐carboxylate (I) is methylated and subsequently coupled with the ketones and aldehydes (III) to form the lactones (IV), together with the 2‐vinylindole‐3‐carboxylic acids (V).
ChemInform Abstract: Superoxide Anion Radical (O2·‐)‐Mediated Base‐Catalyzed Autoxidation of α‐Keto Enols.
Authors: FRIMER A. A. , GILINSKY‐SHARON P. , ALJADEFF G. , ROSENTAL Z.
Published: May 2016

Autoxidation of the hydroxycyclohexadienones (I) in the presence of the superoxide anion radical, generated from KO2 and a crown ether, produces the lactols (II).
ChemInform Abstract: An Unexpected Aromatic SN2′ Substitution of a 4‐Bromobenzopyran.
Authors: HOUGE‐FRYDRYCH C. S. V. , MARSH A. , PINTO I. L.
Published: May 2016

The 4‐bromodihydrobenzopyran (I) reacts with the carboxamides (II) in the presence of a base to give the 5‐substituted dihydrobenzopyrans (III).
ChemInform Abstract: Trifluorothioacetaldehyde.
Authors: SCHULER B. , SUNDERMEYER W.
Published: May 2016

Trifluoroacetaldehyde hydrate (I) reacts with 1,2‐ethanedithiol (II) to give the dithioacetal (III) which is selectively oxidized, yielding the dithiolane 1,1‐dioxide (IV).
ChemInform Abstract: Formation of Isopropylidenepyridoxines. A Convenient Method for the Preparation of 2,2,8‐Trimethyl‐4H‐1,3‐dioxino(4,5‐c)pyridin‐5‐ylmethanol from Pyridoxine Hydrochloride.
Authors: WU Y. , AHLBERG P.
Published: May 2016

An improved and more reliable method of preparation of the title compound (III) is reported.
ChemInform Abstract: Diisophorone and Related Compounds. Part 22. 8,11a‐Methanocycloocta(d,e)quinazolines: Diisophoranes Incorporating the Pyrimidine Ring System.
Authors: KURZER F. , LANGER S. S.
Published: May 2016

While corresponding systems incorporating a dioxepane, pyridine, diazepine or thiazine moiety are known, the title compounds (IV)/(V) and the oxazine analogue (VIII) represent novel ring systems.
ChemInform Abstract: Synthesis of Fused Polyazapolycyclic Compounds Through Condensation of Diaminoalkanes with Carbonyl Compounds.
Authors: BLACK D. STC. , CRAIG D. C. , GIITSIDIS O. , READ R. W. , SALEK A. , SEFTON M. A.
Published: May 2016

The diaminopropanes (I) react with glyoxal (II) to give the bis(hexahydropyrimidines) (III) which are converted into the tetranitro derivatives (V) upon treatment with nitric acid (IV).
ChemInform Abstract: Syntheses of 1,3,6,8,10,11,14‐Heptaazapentaphene‐2,4,7,9(14H,3H,8H,11H)‐tetrones (Angular Mixed Flavins), 1,3,5,6,8,10,11,14‐Octaazapentaphene‐2,4,7,9(14H,3H,8H,11H)‐tetrones (Angular Doubled Flavins), and Their Related Compounds.
Authors: YONEDA F. , KOGA M. , TANAKA K. , YANO Y.
Published: May 2016

The title compounds (VI) and (VIII) and other related polyazapolycyclic compounds are prepared via the Vilsmeier route.
ChemInform Abstract: The Thiophene Analogue of Porphyrin: Tetrathiaporphyrin Dication (IVb).
Authors: VOGEL E. , ROEHRIG P. + , SICKEN M. , KNIPP B. , HERRMANN A. , POHL M. , SCHMICKLER H. , LEX J.
Published: May 2016

Furfuryl alcohol (I) is tranformed into the dication (IVb) (having space group P1 with Z=2) via a remarkably straightforward sulfur/oxygen exchange in (IIIa) to give (IIIb) (P21/c with Z=2).
ChemInform Abstract: Macrolactonization of β‐Hydroxy Acids. Crystal Structures of the Pentolide and the Hexolide from (R)‐3‐Hydroxybutanoic Acid. Molecular Modeling Studies of the Tetrolide.
Authors: SEEBACH D. , BRAENDLI U. + , MUELLER H.‐M. + , DOBLER M. , EGLI M. , PRZYBYLSKI M. , SCHNEIDER K.
Published: May 2016

Under Yamaguchi's macrolactonization conditions, the oligolides (IIIa)‐(IIIc) and higher oligomers are formed from (R)‐(I); while there is hardly any effect of concentration, change of temp. has a pronounced effect of product ratios except for (IIIb) which is constantly ca. 35% of the product mixture.
ChemInform Abstract: Synthesis of Halothiophene S,C‐Ylides and the Corresponding 1,4‐Oxathiocines.
Authors: METH‐COHN O. , VUORINEN E. , MODRO T. A.
Published: May 2016

Rhodium(II) acetate‐catalyzed reaction of the thiophenes (I) with the diazo‐β‐dicarbonyl compounds (II) produces the ylides (III) at room temperature.
ChemInform Abstract: Transformation of Diethyl Phosphite in the Presence of Mn2(CO)10.
Authors: MOSKALENKO M. A. , KARDANOV N. A. , TERENT'EV A. B. , GODOVIKOV N. N.
Published: May 2016

Heating of diethyl phosphite (I) with methyl bromoacetate (II) in the presence of dimanganese decacarbonyl gives triethyl phosphate (III), diethyl ethylphosphonate (IV), methyl acetate (V), and dimethyl succinate (VI).
ChemInform Abstract: Metal Complexes of Functional Isocyanides. Part 19. Vinyl and Chlorovinyl Isocyanide Complexes.
Authors: FEHLHAMMER W. P. , BECK G.
Published: May 2016

The chlorovinyl isocyanide‐Cr complexes (II), (IV), and (V) are synthesized by elimination of chloride from the tetra‐ and trichloroethyl isocyanide‐Cr complexes (I) and (III) according to the scheme.
ChemInform Abstract: Reactions of an Imidoyl Halide with Manganese Carbonyl Complexes.
Authors: MOTZ P. L. , ALEXANDER J. J. , CAMPANA C. F.
Published: May 2016

The carbonylate anion of (II) reacts with (I) to give the product (III) (space group P1, Z=2) which results from head‐to‐tail coupling of two imidoyl groups and reduction of the internal C=N bond.
ChemInform Abstract: Synthesis and Structure of a New Type of Chiral Organoiron and Organoruthenium Complexes.
Authors: ADAMS C. M. , HAFNER A. , KOLLER M. , MARCUZZI A. , PREWO R. , SOLANA I. , VINCENT B. , VON PHILIPSBORN W.
Published: May 2016

The synthesis of 36 complexes of type (III), three of type (IX) and five of type (XII) by thermal, selective CO ligand displacement in the corresponding tricarbonyl precursors is described as demonstrated for the examples given in the scheme.
ChemInform Abstract: Redox Regulation in Ruthenium(II) Complexes of 2,6‐Bis(N‐pyrazolyl)pyridine Ligands: Synthetically Versatile Analogues of 2,2′:6′,2′′‐Terpyridine.
Authors: JAMESON D. L. , BLAHO J. K. , KRUGER K. T. , GOLDSBY K. A.
Published: May 2016

A new family of planar tridentate ligands (III) and (IV), which are structural analogues to terpyridine with the added feature that the ligand superstructure can be conveniently varied, are prepared according to the scheme.
ChemInform Abstract: Oligomeric Dicyanobis(polypyridine)ruthenium(II) Complexes. Synthesis and Spectroscopic and Photophysical Properties.
Authors: BIGNOZZI C. A. , ROFFIA S. , CHIORBOLI C. , DAVILA J. , INDELLI M. T. , SCANDOLA F.
Published: May 2016

The synthesis of the complexes (III) and (V) are carried out with a 10‐fold excess of (II) to minimize the formation of polymeric species.
ChemInform Abstract: Vinylidene Transition‐Metal Complexes. Part 9. Synthesis and Reactivity of Vinylidene Rhodium Complexes Containing C=CHtBu and C=CHCO2Me as Ligands.
Authors: WERNER H. , BREKAU U.
Published: May 2016

The square‐planar alkyne Rh complexes (I) bearing at least one electron withdrawing substituent at the C≡C triple bond are prepared from (III) and the alkynes (II).
ChemInform Abstract: Building Units of Oligosaccharides. Part 44. Synthesis of KDO‐Containing Tri‐ and Tetrasaccharide Sequences of the Inner Core and Lipoid A Region of Lipopolysaccharides.
Authors: PAULSEN H. , KROGMANN C.
Published: May 2016

The glycosyl acceptor (I), which contains two glycosidically β(1 → 6) linked 2‐amino‐2‐deoxy‐D‐glucose residues, is used for the synthesis of the title compounds (IIa) and (IIb).
ChemInform Abstract: A Rapid Entry to Carbocycles from Carbohydrates via Intramolecular Nitrone Cycloaddition.
Authors: SHING T. K. M. , ELSLEY D. A. , GILLHOULEY J. G.
Published: May 2016

The acetonide (I), obtained from D‐ribose, is coupled with vinylmagnesium bromide (II) and then oxidized to give the vinyllactol (IV).
ChemInform Abstract: Nucleotides. Part 32. Synthesis of 2′‐5′ Connected Oligonucleotides. Prodrugs for Antiviral and Antitumoral Nucleosides.
Authors: HERDEWIJN P. , CHARUBALA R. , DE CLERCQ E. , PFLEIDERER W.
Published: May 2016

Coupling of cytotoxically and antivirally active nucleosides with diadenylates by the phosphotriester approach leads to the title prodrugs, e.g. (I) and (II).
ChemInform Abstract: Enantiomerically Pure 7‐Oxabicyclo(2.2.1)hept‐5‐en‐2‐yl Derivatives (“Naked Sugars”) as Synthetic Intermediates. Part 8. Total Synthesis of 2‐(β‐D‐Ribofuranosyl)thiazole‐4‐carboxamide (Tiazofurin) and of Precursors of ribo‐C‐Nucleosides.
Authors: BIMWALA R. M. , VOGEL P.
Published: May 2016

Precursors of ribo‐C‐nucleosides, e.g. (V) and (VII), and tiazofurin (XI) are synthesized starting from the 7‐oxanorbornane derivative (I).
ChemInform Abstract: Preparation of 1‐(2,3‐Dideoxy‐β‐D‐glycero‐pent‐2‐enofuranosyl)thymine (d4T) and 2′,3′‐Dideoxyadenosine (ddA): General Methods for the Synthesis of 2′,3′‐Olefinic and 2′,3′‐Dideoxy Nucleoside Analogues Active Against HIV.
Authors: MANSURI M. M. , STARRETT J. E. JUN. , WOS J. A. , TORTOLANI D. R. , BRODFUEHRER P. R. , HOWELL H. G. , MARTIN J. C.
Published: May 2016

Three different synthetic routes for the production of the 2',3'‐unsaturated nucleoside (Va) are reported.
ChemInform Abstract: Synthesis of (+)‐Aspicilin Using Building Blocks from Renewable Resources.
Authors: QUINKERT G. , FERNHOLZ E. , ECKES P. , NEUMANN D. , DUERNER G. +
Published: May 2016

The 18‐membered lichen macrolide (I) is prepared in 15 steps with an overall yield of 13% from D‐mannose.
ChemInform Abstract: Synthesis of New Benzopyrans Related to Podophyllotoxin.
Authors: JURD L.
Published: May 2016

Starting from the reaction between the Mannich base (I) and the diketone (II) the benzopyran (VI), the highly active structural analogue of the antitumor drug podophyllotoxin (VII), can be prepared.
ChemInform Abstract: New Cell Growth‐Inhibitory Cyclohexadienone Derivatives (I)‐(III) from Hypericum calycinum L.
Authors: DECOSTERD L. A. , STOECKLI‐EVANS H. , CHAPUIS J.‐C. , SORDAT B. , HOSTETTMANN K.
Published: May 2016

The extract of the aerial parts of H. calycinum exhibits in vitro growth‐inhibitory activity against the Co‐115 human colon carcinoma cell line.
ChemInform Abstract: Ab initio Studies of Molecular Structures and Energetics. Part 4. Hexacoordinated NF‐ 6 and CF2‐ 6 Anions.
Authors: EWIG C. S. , VAN WAZER J. R.
Published: May 2016

The energies, equilibrium molecular structures, and vibrational frequencies of the title anions are computed employing the second‐order perturbation approximation (MP2) for the energy.
ChemInform Abstract: Sulfur Compounds. Part 130. Raman Spectroscopic Discovery of the Hydrogenthiosulfate Anion, HSSO‐ 3, in Solid NH4HS2O3.
Authors: STEUDEL R. , PRENZEL A.
Published: May 2016

Reaction of (NH4)2S2O3 and conc.
ChemInform Abstract: Synthesis and Crystal Structure of (S4N3)2Se2Cl10, (S4N3)2Se2Cl6 and ((S4N3)SeCl5)n.
Authors: STAMMLER H. G. , WEISS J.
Published: May 2016

The title compounds (III) and (IV), prepared as outlined in the scheme, are both monoclinic and crystallize in space group P21/a, Z=2 and P21/c, Z=4, respectively.
ChemInform Abstract: Michael Type Addition Reactions of Some Enamines to Arylidenepyrazolones.
Authors: ABDEL‐RAHMAN M. , ABDEL‐GHANY H.
Published: May 2016

Heating the benzylidenepyrazolones (I) with the piperidinocyclohexene (II) in acetonitrile results in the formation of the 2‐substituted 1‐piperidinocyclohexenes (III), whereas coupling of (Ia) ‐ (Ic) with the morpholinocyclohexene (IV) under similar conditions yields the 3‐substituted 2‐morpholinocyclohexenes (V).
ChemInform Abstract: Aminolead Compounds as a New Reagent for Regioselective Ring Opening of Epoxides.
Authors: YAMADA J. , YUMOTO M. , YAMAMOTO Y.
Published: May 2016

The trialkyllead bromides (I) are treated with lithium diethylamide (II) to generate the trialkyllead amides (IIIa) and (IIIb).
ChemInform Abstract: Direct and Bromine‐Atom Initiated Photodecompositions of N‐Acetyl‐N‐bromohexanamide.
Authors: CHOW Y. L. , ZHAO D.‐C.
Published: May 2016

Photolysis of (I) in the presence of an alkene gives high yields of (II) via the imidyl radical Me‐(CH2)4‐CO‐N·‐Ac.
ChemInform Abstract: A New Amino Protecting Group Readily Removable with Near Ultraviolet Light as an Application of Electron‐Transfer Photochemistry.
Authors: HAMADA T. , NISHIDA A. , YONEMITSU O.
Published: May 2016

The (methoxyaryl)alkylbenzenesulfonyl chlorides (I) react with the phenethylamine (II), producing the sulfonamides (III).
ChemInform Abstract: Hydride‐Mediated Homogeneous Catalysis. Catalytic Reduction of α,β‐Unsaturated Ketones Using ((Ph3P)CuH)6 and H2.
Authors: MAHONEY W. S. , STRYKER J. M.
Published: May 2016

Hydride reduction methodology catalytic in the hydride source is demonstrated using stable copper(I) complexes and molecular hydrogen.
ChemInform Abstract: Reduction of Methylene Blue by Sulfide Ion in the Presence and Absence of Oxygen: Simulation of the Methylene Blue‐O2‐HS‐ CSTR Oscillations.
Authors: RESCH P. , FIELD R. J. , SCHNEIDER F. W. , BURGER M.
Published: May 2016

A mechanism is proposed that reproduces the oscillations seen during the methylene blue catalyzed reduction of O2 by HS‐ in a continuous‐flow stirred tank reactor (CSTR).
ChemInform Abstract: One‐Pot Two‐Steps Synthesis of 1,2‐Diol.
Authors: FRINGUELLI F. , GERMANI R. , PIZZO F. , SAVELLI G.
Published: May 2016

The olefins (I) are epoxidized with MCPBA and then subjected to acidic hydrolysis, yielding the vicinal diols (II).
ChemInform Abstract: Hydrocarboxylation of Isoprene Catalyzed by Iodocarbonylrhodium Derivatives. Spectroscopic Evidence for Participation of H+···Rh(CO)2I2‐ Tight Ion Pairs and cis‐Rh(CO)2(H2O)I in Catalysis.
Authors: GARLASCHELLI L. , MARCHIONNA M. , IAPALUCCI M. C. , LONGONI G.
Published: May 2016

Hydrocarboxylation of isoprene (I), catalyzed by iodocarbonylrhodium derivatives, can be controlled to give either pyroterebic acid (IV) or its lactone (V).
ChemInform Abstract: Palladium‐Catalyzed Double Carbonylation of Alkyl Iodides Bearing a Perfluoroalkyl Group.
Authors: URATA H. , ISHII Y. , FUCHIKAMI T.
Published: May 2016

The fluoroalkyl iodides (I) are carbonylated in the presence of the amines (II) and a Pd catalyst to form the α‐oxo carboxamides (IV), together with the amides (V).
ChemInform Abstract: Ritter Reactions. Part 5. Further Investigation of the 3‐Azatricyclo(5.3.1.04,9)undec‐2‐ene System.
Authors: BONG I. C. C. , UNG A. T. , CRAIG D. C. , SCUDDER M. L. , BISHOP R.
Published: May 2016

The monohydrate of compound (I) is prepared in a Ritter reaction from (II) and acetonitrile as previously published (space group P21 with Z=2).
ChemInform Abstract: Derivatives of α‐Trifluoromethylmalic Acid and Their Reactions.
Authors: SOLOSHONOK V. A. , YAGUPOL'SKII YU. L. , KUKHAR' V. P.
Published: May 2016

Dehydration of the title compound (IIIa) affords (V) in high yield.
ChemInform Abstract: Nickel(0)‐Induced CC‐Coupling of CO2 with 1,3‐Butadiene to Linear C13‐Acids.
Authors: HOBERG H. , BAERHAUSEN D. +
Published: May 2016

Fluorinated pyridine‐nickel systems induce a new coupling reaction between 1,3‐butadiene (I) and CO2 (II) to give mixtures of the linear C13‐acid esters (IV)‐(VII) with three or four C=C double bonds and terminal carboxylic groups.
ChemInform Abstract: A Novel Radical Chain Reaction of Xanthic Anhydrides. Further Observations on the Intermediacy of Alkoxythiocarbonyl Radicals in the Barton‐McCombie Reaction.
Authors: FORBES J. E. , ZARD S. Z.
Published: May 2016

Thermolytic or photolytic cleavage of the xanthic anhydrides (I) gives the dithiocarbonates (II) via radicalic intermediates.
ChemInform Abstract: Synthesis of 7,7‐Dimethylbicyclo(3.3.0)octane Derivatives by Acylation of the 4‐Methyl‐3‐penten‐1‐ynedicobalt Hexacarbonyl Complex.
Authors: VERETENOV A. L. , GYBIN A. S. , SMIT V. A. , CHERTKOV V. A. , SHASHKOV A. S.
Published: May 2016

Starting with isobutyraldehyde (I), the methylpentenynecobalt carbonyl complex (VI) is prepared via the intermediates (III) and (V).
ChemInform Abstract: Synthesis of a Potential Steroid Intermediate by Anionic Oxy‐Cope Rearrangement.
Authors: SATHYAMOORTHI G. , THANGARAJ K. , SRINIVASAN P. C. , SWAMINATHAN S.
Published: May 2016

The cyclohexenylvinylcyclohexanol (X) undergoes base‐induced ring closure to form the unsaturated bicyclic ketone (XI).
ChemInform Abstract: Synthesis of 7‐Fluoro‐9,10‐dihydro‐2‐phenanthrylalkanoic Acids.
Authors: EIRIN A. , FERNANDEZ F. , GOMEZ G. , LOPEZ C. , SANTOS A.
Published: May 2016

The nitrophenanthrene (I) is converted to the fluoro analogue (VI) via reduction, diazotization, and thermolysis of the diazonium hexafluorophosphate (V).
ChemInform Abstract: A Novel Method for Generation of Enolizable N‐Trimethylsilylaldimines and Application to β‐Lactam Synthesis.
Authors: UYEHARA T. , SUZUKI I. , YAMAMOTO Y.
Published: May 2016

N,N‐Bis(trimethylsilyl)formamide (I) reacts with the organolithium compounds (II) to give the intermediate alkoxides (III) which form the aldimines (IV).
ChemInform Abstract: Five‐Membered 2,3‐Dioxoheterocycles. Part 16. Synthesis of 1,4‐Disubstituted 5‐Aryltetrahydropyrrole‐2,3‐diones by the Reaction of Diethoxalylacetone with Azomethines.
Authors: ANDREICHIKOV YU. S. , GEIN V. L. , KON'SHINA L. O. , SHAPET'KO N. N.
Published: May 2016

The reaction between the title compounds (I) and (II) is investigated for the first time.
ChemInform Abstract: Fischer Indolization and Related Compounds. Part 21. Direction on the Cyclization in the Fischer Indolization of Ethyl Pyruvate 2‐(p‐ or m‐Substituted Phenyl)phenylhydrazones.
Authors: ISHII H. , TAKEDA H. , HAGIWARA T. , SAKAMOTO M. , KOGUSURI K. , MURAKAMI Y.
Published: May 2016

The Fischer indolization reaction (FIR) of the readily available phenylhydrazones (IV) under acidic conditions gives the indoles (V) and (VI) as main products whereas the yields of (V) and (VI) are much lower in the thermal sigmatropic reaction of (IV) producing preferentially the compounds (I).
ChemInform Abstract: Synthesis of Cyclic Hydroxyureas.
Authors: SULSKY R. , DEMERS J. P.
Published: May 2016

The N‐benzyloxyureas (I) undergo selective base‐induced ring closure with the α,ω‐dibromoalkanes (II), yielding the 1,3‐diaza heterocycles (III).
ChemInform Abstract: Synthesis and Reactions of 5‐(Tributylstannyl)isoxazoles.
Authors: KONDO Y. , UCHIYAMA D. , SAKAMOTO T. , YAMANAKA H.
Published: May 2016

Ethynyltributylstannane (I) undergoes 1,3‐dipolar cycloaddition reaction with the nitrile oxides (II) to yield the tributylstannylisoxazoles (III).
ChemInform Abstract: A New Synthesis of 4‐Substituted Coumarins.
Authors: PATRA A. , MISRA S. K.
Published: May 2016

Since 4‐substituted coumarins possess a broad spectrum of biological activities, a new procedure for their synthesis is developed.
ChemInform Abstract: A Convenient One‐Pot Synthesis of 3‐Thio‐Substituted Coumarins.
Authors: AHLUWALIA V. K. , ALAUDDIN M. , KHANDURI C. H. , MEHTA V. D.
Published: May 2016

Alkylation of the heterocyclic thiols (I) with chloroacetonitrile (II) yields the cyanomethyl sulfides (III) which undergo ring closure with the o‐hydroxybenzaldehydes (IV), forming the coumarinimines (V).
ChemInform Abstract: Synthesis of 3‐Aryl‐4‐acetyl‐1H‐pyrazolo(3,4‐b)pyridines and 3‐Aryl‐4‐acetyl‐1H‐pyrazolo(4,3‐c)pyridines.
Authors: BISAGNI E. , RAUTUREAU M. , HUEL C.
Published: May 2016

Lithiation of the 2‐chloropyridin‐4‐yl ketone acetal (I) followed by coupling with the aromatic aldehydes (II) yields the carbinols (III) which are subjected to Swern oxidation, forming the 2‐chloro‐3‐aroylpyridines (IV).
ChemInform Abstract: Alkylation and Rearrangement of Lithiated 3‐Methyl‐1,2‐benzisoxazoles.
Authors: OLIVER J. E. , WATERS R. M. , LUSBY W. R.
Published: May 2016

The 3‐methylbenzisoxazoles (I) are deprotonated at the methyl group upon treatment with LDA in the presence of the bromide (II) to give the 3‐undecylbenzisoxazoles (III).
ChemInform Abstract: Acylation and Oxidation of 4‐Chloro‐6‐hydroxyaminopyrimidines. Synthesis of 4‐Chloro‐6‐nitro(nitroso)pyrimidines.
Authors: YAGODINA O. V. , SEDOVA V. F. , MAMAEV V. P.
Published: May 2016

The chlorohydroxylaminopyrimidines (III) are coupled with the carboxylic chlorides (IV) or the isocyanates (VII) to give the acyl derivatives (V) or (VI) and the biscarbonyl compounds (VIII).
ChemInform Abstract: Oxidation of Hydroxyamino‐ and Nitrosopyrimidines. Synthesis of Substituted 2‐ and 4‐Nitropyrimidines.
Authors: MOSKALENKO G. G. , SEDOVA V. F. , MAMAEV V. P.
Published: May 2016

Oxidation of the nitrosopyrimidines (I) or (III) gives the corresponding nitro derivatives (II) or (IV), whereas from the hydroxyaminopyrimidines (V) and (VII), the azoxy compounds (VI) and (VIII) are obtained.
ChemInform Abstract: Synthesis and Structure Activity Relationship in Aryloxyalkylamines.
Authors: AGARWAL S. K. , SAXENA A. K. , JAIN P. C. , ANAND N. , SUR R. N. , SRIMAL R. C. , DHAWAN B. N.
Published: May 2016

Three compounds of type (III) and (VII) as well as five compounds of type (XI) are prepared.
ChemInform Abstract: Piperazine Derivatives of Benzimidazole as Potential Anthelmintics. Part 1. Synthesis and Activity of Methyl‐5‐(4‐Substituted‐piperazin‐1‐yl)benzimidazole‐2‐carbamates.
Authors: SANCHEZ‐ALONSO R. M. , RAVINA E. , SANTANA L. , GARCIA‐MERA G. , SANMARTIN M. , BALTAR P.
Published: May 2016

The piperazinylnitroanilines (III), prepared by coupling the piperazines (I) with the chloronitroaniline (II), are reduced and subsequently treated with the S‐methylisothiourea (IV) to produce the piperazinylbenzimidazoles (V).
ChemInform Abstract: Aminoquinone Reactions. Part 6. 5‐Arylamino‐8,9,10,11‐tetrahydrobenzo‐(a)phenazines and 6‐Arylamino‐2,3‐dicyanobenzo(f)quinoxalines.
Authors: KALLMAYER H.‐J. , STASS C.
Published: May 2016

The o‐naphthoquinones (II) react with the vicinal diamines (I) to form the corresponding benzoquinoxalines (III).
ChemInform Abstract: Reactions of Cα,O‐Dilithio Oximes with Functionalized Carbonyl Compounds. Part 1. Reaction with 1,2‐Diketones.
Authors: HUSSEIN A. Q. , JARRAR A. A. , MADI A. S.
Published: May 2016

Twofold lithiation of the oximes (I) followed by reaction with the aromatic 1,2‐diketones (II) results in cyclization to give the dihydroxydihydro‐1,2‐oxazines (III).
ChemInform Abstract: Synthesis of a 3‐Acetoxy‐6‐phenylpyrone and Its Conversion to a Pyrido‐(1,4)benzodiazepine.
Authors: WUSTROW D. J. , WIERENGA W.
Published: May 2016

Lithiation of the methyl ketone (I), followed by acylation with the aromatic acid chloride (IV) and intramolecular cyclization of the diketone (V), produces the 3‐acetoxy‐4‐pyrone (VI).
ChemInform Abstract: Synthesis and Immobilization of New Crown Ethers Derived from D‐Mannitol for the Resolution of Free Amino Acids.
Authors: JOLY J.‐P. , GROSS B.
Published: May 2016

The mannitol derivative (I) is coupled with the bis(chloroethyl) ether (II) to form the bis(chloroethoxyethyl) ether (III) which undergoes cyclization with the resorcinols (IV), yielding the crown ethers (Va) and (Vb).
ChemInform Abstract: Organic Heterocyclothiazenes. Part 11. Dithiatetrazocines and Dithiadiazolium Chlorides.
Authors: AMIN M. , REES C. W.
Published: May 2016

A reinvestigation of the reaction of the compounds (Ia) and (II) fails to increase the yield of the dithiatetrazocine (IIIa) but uncovers a new product (IVa).
ChemInform Abstract: Pseudochalcogen Compounds. Part 21. Synthesis and Structure of Phosphorus(III) and Phosphorus(V) Organocyanamides.
Authors: KOEHLER H. + , JAEGER L. + , GEBEL W.
Published: May 2016

The P(III) and P(V) organocyanamides (III)‐(VI) are synthesized by the reaction of the corresponding P chlorides with the metal cyanamides (II) as demonstrated for the examples (III).
ChemInform Abstract: New Prophosphatranes: Novel Intermediates to Five‐Coordinate Phosphatranes.
Authors: SCHMIDT H. , LENSINK C. , XI S. K. , VERKADE J. G.
Published: May 2016

The reaction of the tetramine (I) with ClP(NMe2)2 (II) or P(NMe2)3 (III), as shown in the scheme, yields the phosphatrane precursor (IV).
ChemInform Abstract: Concave Functionality: Intracavity Phosphine Oxide as a Locus of Complexation.
Authors: FRIEDRICHSEN B. P. , WHITLOCK H. W.
Published: May 2016

Because of the interest of the design of host molecules capable of binding neutral organic guests the exo‐exo‐(IV) and (VI) and the endo‐exo‐(V) and (VII) bifunctional cages are prepared.
ChemInform Abstract: Reaction of Dichlorocarbene with Vinyl Methyl Selenide and Divinyl Selenide.
Authors: MOLCHANOV A. P. , KOSTIKOV R. R. , AMOSOVA S. V. , POTAPOV V. A.
Published: May 2016

On reaction with dichlorocarbene, the title compounds (I) or (IV) afford the hitherto unknown adducts (III) or (V) and (VI), respectively.
ChemInform Abstract: Synthesis and Spectral Properties of Bis(alkyltelluro)ethynes, RTeCCTeR (R: Me, Et).
Authors: GEDRIDGE R. W. JUN. , HIGA K. T. , HARRIS D. C. , NISSAN R. A. , NADLER M. P.
Published: May 2016

The reaction mechanism is discussed and optimum conditions are given.
ChemInform Abstract: Difunctionalization of Primary Aromatic Amines with Ethylene. Synthesis of μ‐Arylnitrilobis(ethane‐2,1‐diyl)dimercury(II) Complexes. Crystal Structure of 2,4,6‐Me3C6H2N(CH2CH2HgCl)2.
Authors: DEACON G. B. , GATEHOUSE B. M. , GUDDAT L. W. , NEY S. C.
Published: May 2016

Reaction of the aromatic amines (I) and (V) with mercuric acetate (II) and ethylene (III) leads to the formation of the title compounds (IV).
ChemInform Abstract: Reactions of Sterically Hindered Stannylphosphines: Synthesis of the First Tin‐Substituted Diphosphene.
Authors: HAENSSGEN D. + , ALDENHOVEN H. , NIEGER M.
Published: May 2016

Reaction of lithium (tri‐tert‐butylstannyl)phosphide (I) with 2,4,6‐tri‐tert‐butylphenyldichlorophosphane (II) leads to the formation of (2,4,6‐tri‐tert‐butylphenyl)‐tri‐tert‐butylstannyldiphosphene (III).
ChemInform Abstract: Hydrostannation of Methyl(carboxysulfamoyl)triethylammonium Hydroxide Inner Salt: A New Route to Tributyltin Isocyanate.
Authors: RATIER M. , KHATMI D. , DUBOUDIN J. G. , MINH D. T.
Published: May 2016

Tributylstannyl isocyanate (III) which is prepared from the inner salt (I) and tributylstannane (II) as mentioned in the title is observed as a by‐product in the formation of vinylic stannanes, e.g. (V), by dehydration of 1‐stannylcycloalkanols such as (IV) with the reagent (I).
ChemInform Abstract: Terminal Aminophosphinidene Complexes. A New Approach.
Authors: MERCIER F. , DESCHAMPS B. , MATHEY F.
Published: May 2016

The thermal decomposition of the (amino)phosphirene‐W complex (I) at ca. 130 °C provides an access to the transient (amino)phosphinidene‐W compound (II) which is trapped by 2,3‐dimethylbutadiene (III), EtOH, or NHEt2 (V) to give the expected adducts (IV) and (VI).
ChemInform Abstract: A Novel Tetranuclear Manganese Complex That Displays Multiple High‐Potential Redox Processes. Synthesis, Structure, and Properties of ((Mn2(TPHPN)(O2CCH3)(H2O))2O)(ClO4)4·2 CH3OH.
Authors: CHAN M. K. , ARMSTRONG W. H.
Published: May 2016

The novel tetranuclear complex (III) with a septadentate ligand and with an average manganese oxidation state of +2.5 is prepared and crystallographically characterized (space group P21/n, Z=2).
ChemInform Abstract: Lipophilic Technetium Complexes. Part 6. Neutral Oxotechnetium(V) Complexes with Monothiole/Tridentate Dithiole Coordination.
Authors: PIETZSCH H.‐J. , SPIES H. , HOFFMANN S.
Published: May 2016

The Tc(V) title complexes (IV) are characterized by IR, NMR, and UV/VIS data.
ChemInform Abstract: Structure and Reactivity of ReH4(PMe2Ph)+ 4.
Authors: LUNDER D. M. , GREEN M. A. , STREIB W. E. , CAULTON K. G.
Published: May 2016

Protonation of the trihydride (I) with HBF4·OEt2 gives the BF4‐ salt (II) (space group Pcab, Z = 8) of the title cation which neither exchanges with D2 nor reacts with PhC≡CPh, CO, MeCN, or ethylene under mild conditions.
ChemInform Abstract: Binuclear Reaction Products of Grignard Compounds and Transition‐Metal Acetylacetonates ‐ Catalysts of Cross Coupling.
Authors: DOERING M. + , UHLIG E. , DAHLENBURG L.
Published: May 2016

In THF Grignard compounds react with transition‐metal acetylacetonates forming the binuclear complexes (I) (yields for (Ia) and (Ib) 94/25%).