bluuebunny/crossref_metadata_2025 huggingface dataset:
Short-term results of isolated phlebectomy with preservation of incompetent great saphenous vein (ASVAL procedure) in primary varicose veins disease
Authors: Zolotukhin Igor A , Seliverstov Evgeny I , Zakharova Elena A , Kirienko Alexander I
Published: October 2016

Objective

To establish an effect of isolated phlebectomy in patients with incompetent great saphenous vein (Ambulatory Selective Varices Ablation under Local anesthesia (ASVAL) procedure) on the reflux and diameter of the trunk and to assess recurrence rate of varicose veins at one year.

Material and methods

We conducted a prospective study on patients with primary varicose veins and with C2 or C2,3 or C2,3,4 or C2,4 classes of chronic venous disease and great saphenous vein incompetence. The study included 67 patients (51 women and 16 men; 75 limbs in total). Age varied from 17 to 71 years; mean age was 46.8 years (SD 13.9). We recorded the presence or absence of reflux in the great saphenous vein with duplex ultrasound before and after surgery. The recurrence of varicose veins was evaluated at 12 months. All the patients underwent isolated phlebectomy with preservation of incompetent great saphenous vein (ASVAL procedure) under local anesthesia.

Results

At one year after removing of tributaries of the incompetent trunk, 66% of them were competent. Reflux persisted in 17% of great saphenous veins with reflux above mid-thigh and in 61% of trunks with reflux extended below the mid-thigh (p = 0.0004). The diameter of all the veins decreased significantly no matter reflux disappeared or not. Varicose veins reoccurred in 13.5% cases. In 6.5% of limbs with a reflux above the mid-thigh, the recurrence was registered at one year, while in the limbs with the reflux below the mid-thigh at a baseline, the recurrence rate was 25% (p = 0.036).

Conclusion

Isolated phlebectomy with a preservation of incompetent great saphenous vein leads to disappearance of reflux in a majority of cases and to significant decrease of vein diameter in all the cases. ASVAL procedure could be considered as a less aggressive and less expensive approach in selected cases. Clear indications for isolated phlebectomy need to be established.
Embeddedness and migrant tourism entrepreneurs: A Polanyian perspective
Authors: Su Xiaobo , Chen Zhigang
Published: October 2016

Tourism embodies flows of tourists, capital and information, as well as migration, including migrants who operate businesses. How do migrant entrepreneurs negotiate social ties and economic activities in their destinations? To answer this question, the paper draws on Polanyi’s work on embeddedness to explore migrant tourism entrepreneurs (MTEs) and their modes of integration in the practice of social and economic life. We argue that MTEs are situated in a complex matrix in which they must build economic connections with locals and government officials, yet maintain a respectful distance with local groups, and develop embedded ties with other fellow migrants and tourists. Embeddedness, juxtaposed with distance, indicates that in tourist destinations, mixed patterns of economic and social relations significantly influence MTEs’ social and economic life. A Polanyian perspective on embeddedness can provide useful theoretical tenets to understand entrepreneurial activities in a mobile world.
Interlaminar fracture toughness of flax-epoxy composites
Authors: Bensadoun F , Verpoest I , Van Vuure AW
Published: October 2016

The purpose of this study was to determine the influence of fibre architectures on the interlaminar fracture toughness and tensile toughness of flax fibre epoxy composites. The fracture toughness was investigated for both Mode I (GIC) and Mode II (GIIC) for seven flax-epoxy architectures: one plain weave, two twill 2 × 2 weaves, a quasi-unidirectional and a unidirectional architecture, the UD’s being tested in both [0,90] and [90,0] composite lay-ups. The results of the Mode I and Mode II showed promising results of the flax-epoxy composite performance. The addition of flax fibre increases the GIC and GIIC of the composites over that of the unreinforced brittle polymer by at least two to three times. Further improvements are made with the use of woven textiles. The tensile toughness was found to be a good indicator of the capacity of a material to sustain perforation or non-perforation impact.
Review of Copper Provision in the Parenteral Nutrition of Adults
Authors: Livingstone Callum
Published: October 2016

The essential trace element copper (Cu) is required for a range of physiologic processes, including wound healing and functioning of the immune system. The correct amount of Cu must be provided in parenteral nutrition (PN) if deficiency and toxicity are to be avoided. While provision in line with the standard recommendations should suffice for most patients, Cu requirements may be higher in patients with increased gastrointestinal losses and severe burns and lower in those with cholestasis. The tests of Cu status that are currently available for clinical use are unreliable. Serum Cu concentration is the most commonly ordered test but is insensitive to Cu deficiency and toxicity and is misleadingly increased during the acute phase response. These limitations make it difficult for prescribers to assess Cu status and to decide how much Cu to provide. There is a need for better tests of Cu status to be developed to decrease uncertainty and improve individualization of Cu dosing. More information is needed on Cu requirements in disease and Cu contamination of PN components and other intravenous fluids. New multi–trace element products should be developed that provide Cu doses in line with the 2012 American Society for Parenteral and Enteral Nutrition recommendations. This article discusses the evaluation and treatment of Cu deficiency and toxicity in patients treated with PN.
Comparison of the CADRI and CTS2 for Measuring Psychological and Physical Dating Violence Perpetration and Victimization
Authors: Cascardi Michele , Blank Sean , Dodani Vikash
Published: October 2016

Advancing dating violence (DV) research requires consistent conceptualization and measurement. However, empirical sudies on the measurement of psychological and physical DV perpetration and victimization are uncommon. There were three aims of the current study: (a) to examine the construct validity of psychological and physical DV perpetration and victimization on the Conflict in Adolescent Dating Relationships Inventory (CADRI) and Revised Conflict Tactics Scales (CTS2) using factor analysis; (b) to compare empirically derived DV scales with ones using face valid definitions of psychological and physical DV within each measure; and (c) to compare results obtained from the CADRI with those obtained from the CTS2. A diverse sample of undergraduates ( N = 512; 63.9% female, 50.0% White, 16.2% Black, and 22.9% Latino) completed an online survey. There were two-factor solutions for each survey and DV perpetration and victimization: moderate psychological DV and severe psychological/physical DV on the CADRI; and moderate psychological and physical DV and severe psychological and physical DV on the CTS2. Multiple regression analyses showed that results were similar for empirically and rationally derived scoring methods with one exception: On the CTS2, risk factors associated with moderate DV were not the same as those associated with psychological DV. Moreover, the unique contribution of risk factors to each form of DV depended on which survey was used. In multivariate studies of risk factors associated with psychological and physical DV, the CADRI and CTS2 do not appear to be interchangeable, and may lead to different conclusions about the relative importance of risk factors.
The Role of Shame in the Relation Between Peer Victimization and Mental Health Outcomes
Authors: Irwin Alexandra , Li Joyce , Craig Wendy , Hollenstein Tom
Published: October 2016

Youth who experience peer victimization are at risk of developing mental health problems. However, little is known about the emotional causal mechanisms linking peer victimization with these negative outcomes. This study investigated whether shame mediated this relationship. At three time points (T1-T3), 396 10- to 13-year-olds completed measures of peer victimization, shame (characterological, bodily, and behavioral; shame proneness), and mental health (depression, social anxiety, and externalizing behavior). Three multiple mediation models tested the indirect effects of T1 victimization on T3 mental health through the four T2 shame-related variables. Analyses revealed indirect effects for the shame-related mediators on depression, social anxiety, and externalizing behaviors. Specifically, indirect positive effects for characterological and bodily shame on depression and social anxiety were found, with greater bodily shame linked to higher levels of social anxiety in girls but not boys. In addition, an indirect negative effect for behavioral shame on externalizing problems was found, with higher levels of externalizing problems in victimized boys but not in girls. Finally, an indirect positive effect for shame proneness and externalizing problems was found. To clarify the directionality, three additional mediation models were run with mental health symptoms as predictors of shame and subsequent victimization. Indirect effects for the shame-related mediators were found for all outcomes, specifically bodily shame and shame proneness as mediators between internalizing and externalizing symptoms and victimization. These three models were compared and contrasted with the hypothesized models. In sum, findings support the role of shame as an underlying emotional mechanism of peer victimization, and may guide intervention programs to address the mental health concerns of victimized youth.
Parental Involvement Initiatives: An Analysis
Authors: Hamlin Daniel , Flessa Joseph
Published: October 2016

Educational policies have increasingly promoted parental involvement as a mechanism for improving student outcomes. Few jurisdictions have provided funding for this priority. In Ontario, Canada, the province’s Parents Reaching Out Grants program allows parents to apply for funding for a parental involvement initiative that addresses a local barrier to parent participation. This study categorizes initiatives ( N = 11,171) amounting to approximately 10 million dollars (Can$) in funding from 2009 to 2014 and compares them across school settings. Although results show several key contextual differences, parents across settings identify relatively similar needs for enabling parental involvement, emphasizing parenting approaches for supporting well-being (e.g., nutrition, mental health, and technology use) and skills for home-based learning. However, Epstein’s widely used parental involvement typology conceals these prominent aspects of parental involvement. A modified model of parental involvement is presented that may serve as a guide for enhancing parent participation.
Main helicopter rotor trimming using computational fluid dynamics method in forward flight
Authors: Ma Yimin , Chen Ming , Wang Qiang , Wang Fang
Published: October 2016

In this paper, a computational fluid dynamics trimming method is proposed and compared with wind tunnel experiment and the blade element method. The NASA’s generic ROBIN helicopter model is adopted for transient simulations to obtain the final main rotor trimming conditions. Totally three steps were applied to the computational fluid dynamics method. The first step is associated with no cyclic pitch motion, the second is regarding pure longitudinal cyclic pitch motion and the last is concerning with pure lateral cyclic pitch motion. At the same time, a simple linear equation system between the roll and pitching moment was established to get the final longitudinal and lateral cyclic pitch angles for the main rotor through the above three steps. An overset grid approach was used where the volume around each blade was modeled in an individual overset grid region. The rotor rotation was resolved with three degrees per time-step. Turbulence was modeled with the well-known SST K-omega model with second-order convection. The helicopter was in straight forward flight with an advance ratio of [Formula: see text]. Three sources of stick angles, which are also called rotor trimming angles, were shown and compared with each other. And the corresponding results were also plotted with a type of history plot in the computational fluid dynamics condition. In the simulations, the results became quasi periodic after about 1.5 rotations and four rotor rotations were simulated for each case. The pitch moment coefficient and roll moment coefficient were all trimmed to about zero by the computational fluid dynamics trimming method while moments were not removed thoroughly in the other two source conditions.
Electrospun nanofibre bundles and yarns for tissue engineering applications: A review
Authors: O’Connor Richard A , McGuinness Garrett B
Published: October 2016

Nanofibre membranes produced through the electrospinning process have been studied extensively over the past decade for a number of high demand applications including use as tissue engineered scaffolds. Despite possessing desirable properties including high surface area to volume ratios and enhanced mechanical properties, they ultimately suffer from a lack of cellular infiltration. Variations on the process include the production of highly aligned filaments of electrospun fibres referred to as bundles and yarns. Nanofibre bundle and yarn-based scaffolds have been shown to demonstrate superior cell infiltration rates compared to traditional electrospun nonwovens while also offering the capability to be incorporated into a wider array of post-processing technologies. In this review, fibre collection techniques currently employed within the literature for the fabrication of electrospun bundles and yarns along with their applications in the field of tissue engineering will be discussed.
Becoming-City: Thinking and Writing Differently After Deleuze
Authors: Bright David
Published: October 2016

Becoming-city explores the encounter between Self and Other in Hanoi, Vietnam, through Deleuze’s philosophy of difference. Theory, experience, history, literature, language, and data are combined in order to ask what it is that individuates subject and object. Deleuze’s philosophy of difference is used to explore and push problems of difference and identity to their limits through writing of the encounter between individual and city. This encounter is employed not as metaphor but as the actual process of movement through which events take place and thinking is engendered, leading to possibilities of thinking differently about difference.
Cost savings analysis and toxicity audit of a bevacizumab dose rounding policy at a community cancer center
Authors: Moore Donald C , McVey Gary Neal
Published: October 2016

Purpose

To evaluate the potential cost savings incurred from a policy to round doses of bevacizumab to the nearest vial size. Secondarily, to determine differences in rates of adverse events between patients who had their doses rounded up compared with those who had doses rounded down.

Methods

This study is a retrospective chart review of all patients who received at least one rounded dose of bevacizumab over a period of 22 months. Doses of bevacizumab were calculated based on actual body weight. The calculated dose was then rounded to the nearest 400 or 100 mg vial size. The predicted effect on cost was calculated in US dollars for both the pre-rounded dose and the rounded dose. Adverse events including hypertension, proteinuria, and vascular events were compared between those that received a dose that was rounded up and those with a dose rounded down.

Results

A total of 55 patients received at least one dose bevacizumab between 1 August 2014 and 31 May 2016. A total of 470 doses were administered. The estimated cost savings by rounding bevacizumab doses to the nearest 100 mg during the study time period was $164,617.92. Patients receiving either a dose that was rounded up or rounded down to the nearest 100 mg experienced similar rates of adverse events.

Conclusion

Dose rounding of bevacizumab to the nearest vial size resulted in significant cost savings and did not significantly impact the incidence of adverse events.
Habitus, affordances, and family leisure: Cultural reproduction through children’s leisure activities
Authors: Choi Kimburley WY
Published: October 2016

Informed by Gibson’s affordances and Bourdieu’s habitus, this visual ethnographic study explores parents’ ideas about learning and leisure and the actual domestic leisure children (between three to seven years old) consume in association with socioeconomic status. It is found that parent informants have similar reservations about local education regardless of socioeconomic status. Nevertheless, their different socioeconomic and cultural backgrounds contribute to their different involvement in children’s learning and leisure through their use of the domestic setup, television and computing devices, and toys. Through leisure, middle-class parent informants transmit certain emotions, values, skills, behavioral dispositions, and tastes to their children, which coincide with institutional approaches to learning. The study finds that children’s domestic leisure is largely patterned by materials (domestic setup and leisure-induced appliances), practices (TV and mobile computing usage and toy selection and play) and social structure, and thus links considerably to children’s disparity in academic achievements and attitudes towards learning.
Between marginality and privilege: gaining access and navigating the field in multiethnic settings
Authors: Mayorga-Gallo Sarah , Hordge-Freeman Elizabeth
Published: October 2016

In this article we propose a framework of credibility and approachability for researchers to use as they prepare for fieldwork and write up their data. Highlighting intersectional perspectives from two women and scholars of color, this framework translates the important theoretical critiques of dichotomous thinking (for example, insider-outsider) into methodological practice. We argue that credibility and approachability are not just performed by researchers, but are also perceived by respondents and placed on researchers’ bodies. By conceptualizing credibility and approachability as both performed behaviors and perceived characteristics, we are able to incorporate the researcher’s positionality, the standpoint of the researched, and the power-laden particularities of the interaction in our data analyses and fieldwork reflections for the benefit of both researchers and readers.
Gender differences in computer and information literacy: An exploration of the performances of girls and boys in ICILS 2013
Authors: Punter R Annemiek , Meelissen Martina RM , Glas Cees AW
Published: October 2016

IEA’s International Computer and Information Literacy Study (ICILS) 2013 showed that in the majority of the participating countries, 14-year-old girls outperformed boys in computer and information literacy (CIL): results that seem to contrast with the common view of boys having better computer skills. This study used the ICILS data to explore whether the achievement test used in this study addressed specific dimensions of CIL and, if so, whether the performances of girls and boys on these subscales differ. We investigated the hypothesis that gender differences in performance on computer literacy items would be slightly in favour of boys, whereas gender differences in performance on information literacy items would be slightly in favour of girls. Furthermore, it was examined whether such differences varied across European countries and if item bias was present. Data was analysed using a confirmative factor analysis model, i.e. a multidimensional item response theory model, for the identification of the subscales, the explorations of gender and national differences, and possible item bias. To a large extent the results support our postulated hypothesis and shed new light on the commonly assumed disadvantaged position of girls and women in modern information society.
Promotoras and the Semantic Gap Between Latino Community Health Researchers and Latino Communities
Authors: Schwingel Andiara , Wiley Angela R. , Teran-Garcia Margarita , McCaffrey Jennifer , Gálvez Patricia , Vizcarra Marcela
Published: October 2016

Promotoras are identified as a unique group of community health workers adept at reducing health disparities. This qualitative study was conducted to better understand perceptions of the term promotora, broadly used in research but not well documented in everyday Latina vocabulary. Six focus groups to better understand perceptions of the term promotora were conducted with 36 Latina women living in three nonmetropolitan areas in Illinois. Results suggest that Latina participants in the study do not understand the meaning of “promotora” in the same way as it is used in the literature. Latina participants understood “promotoras” as referring to people who sell or deliver information, or organize events in the community that are not necessarily related to health events or community health work. Furthermore, they usually understood the term to refer to paid work rather than volunteering. Results underscore the importance of being sensitive to Latinas’ perceptions of community health terminology by assessing their context, needs, and expectations. These findings call researchers’ attention to the need to educate certain Latino communities about the concept of promotoras, with implications for the implementation and dissemination of promotora-led community health programs, as the semantic discrepancy could affect the recruitment of promotoras as well as community participation in the programs they deliver.
Can Student Populations in Developing Countries Be Reached by Online Surveys? The Case of the National Service Scheme Survey (N3S) in Ghana
Authors: Langer Arnim , Meuleman Bart , Oshodi Abdul-Gafar Tobi , Schroyens Maarten
Published: October 2016

This article tackles the question whether it is a viable strategy to conduct online surveys among university students in developing countries. By documenting the methodology of the National Service Scheme Survey conducted in Ghana, we set out to answer three questions: (1) How can a sample of university students be obtained? (2) How can students be motivated to cooperate in online surveys? (3) What kind of devices do students use for completing an online survey? Our results indicate that online strategies can be very useful to reach this particular target group, if the necessary precautions are taken.
Analysis of Risk Factors for Early Type I Endoleaks After Thoracic Endovascular Aneurysm Repair
Authors: Kanaoka Yuji , Ohki Takao , Maeda Koji , Baba Takeshi
Published: October 2016

Purpose: To evaluate risk factors for early (<30 days) type I endoleak following thoracic endovascular aortic repair (TEVAR). Methods: A retrospective study was conducted of 439 consecutive patients (mean age 74.0±10.0 years; 333 men) who underwent TEVAR at a single center between June 2006 and June 2013. Pathologies included 237 aortic arch aneurysms and 202 descending thoracic aortic aneurysms (dTAA). Maximum TAA diameter was 63.6±13.7 mm. Among the distal aortic arch aneurysms, 124 required coverage of the left subclavian artery (LSA), while the remaining 113 arch aneurysms had debranching (n=40), the chimney technique (n=52), and a branched stent-graft (n=13). Eight patients with dilatation of the ascending aorta underwent arch replacement with elephant trunk prior to TEVAR. Predictive factors for type I endoleak were explored in univariate analysis and examined for each outcome using logistic regression models; results are given as the odds ratio (OR) and 95% confidence interval (CI). Results: Among 439 TEVAR cases, 37 (8.4%) had type I endoleaks on imaging at 1 month; 31 were in the 237 arch cases (13.1%). Endoleak investigation by site indicated a low incidence (3.0%) for dTAAs and markedly low (1.4%) in zone 4. Significantly more endoleaks were observed in zones 0–2 than in zone 4 (p<0.001). On univariate analysis, significant associations were found between endoleak and LSA coverage (OR 5.8, 95% CI 2.4 to 14.4, p<0.001), operative time ≥240 minutes (OR 3.7, 95% CI 1.5 to 6.2, p=0.002), and ≥270 mL of contrast (OR 2.8, 95% CI 1.4 to 5.8, p=0.004). Among the aortic branch reconstruction procedures, the chimney technique was the only maneuver associated with a significant risk of endoleak (OR 5.3, 95% CI 2.3 to 11.2, p<0.001). Arch state was not correlated with endoleaks, but ≥38-mm proximal neck diameter (OR 3.6, 95% CI 1.2 to 10.8, p=0.023), stent-graft diameter ≥40 mm (OR 9.9, 95% CI 1.4 to 30.5, p=0.015), and excessively oversized (≥14%) stent-grafts (OR 3.5, 95% CI 1.2 to 10.3, p=0.020) were; the proximal neck length was not correlated with endoleaks if a proximal neck length >10 mm can be secured. Conclusion: Risks for early type I endoleaks after TEVAR for aneurysm were landing zone 0–2, LSA coverage, large proximal neck and stent-graft diameters, excessive oversizing, and the use of the chimney technique.
Comparative Effectiveness of Three Occupational Therapy Sleep Interventions
Authors: Gutman Sharon A. , Gregory Kristin A. , Sadlier-Brown Megan M. , Schlissel Marcy A. , Schubert Allison M. , Westover Lee Ann , Miller Richard C.
Published: October 2016

Although sleep intervention is within the domain of occupational therapy, few studies exist supporting practice. Effectiveness of three sleep interventions was compared: Dreampad Pillow®, iRest® meditation, and sleep hygiene. Twenty-nine participants were randomly assigned to the Dreampad Pillow® ( n = 10), iRest® meditation ( n = 9), and sleep hygiene ( n = 10) groups. In Phase 1, all participants used a 7-day sleep hygiene regimen to reduce poor sleep habits. In Phase 2 (14 days), 10 participants used the Dreampad Pillow® and sleep hygiene, nine used the iRest meditation and sleep hygiene, and 10 continued sleep hygiene only. At intervention-end, the iRest meditation group experienced statistically greater time asleep than both the Dreampad Pillow® ( p < .006, d = 1.87) and sleep hygiene groups ( p < .03, d = 1.80). The Dreampad Pillow® group experienced statistically fewer nighttime awakenings than the iRest® meditation ( p < .04, d = −1.53) and sleep hygiene ( p < .004, d = −1.43) groups. No differences were found between groups in perceived sleep quality, length of time needed to fall asleep, and fatigue level next day. This study provides support for sleep interventions within occupational therapy’s domain.
Is there a relationship between ultrasound scanning ability (sonography) and visuospatial perception or psychomotor ability?
Authors: Chapman Elizabeth , Hagen Suzanne , Gallagher Helen
Published: October 2016

Background

Competent sonography is thought to include a unique combination of skills not yet fully defined. This presents challenges when recruiting the correct people for training. Skills are thought to include visuospatial perception and psychomotor skills, but little is known about the relationship between these aptitudes and scanning ability. This feasibility study explored such relationships, to identify evaluation techniques which may improve selection and recruitment.

Methods

A sample of 30 experienced ultrasound practitioners and 30 trainees at commencement and on completion of training were administered eight tests.

Results

No significant relationships between experienced practitioners’ or trainees’ visuospatial abilities or psychomotor abilities and scanning abilities were found. Results demonstrated that two of the visuospatial perception tests were not influenced by training and therefore, may be measuring the innate skills of ultrasound practitioners. As ultrasound practitioners had not performed any of the tests previously, ranges of scores for each of the eight tests were established for this group. This included measures for psychomotor skills which added to the current body of knowledge for sonography.

Conclusions

Although no significant correlations were found between participants’ visuospatial perception or psychomotor abilities and scanning ability, performance on the Obstetric Structured Assessment Test (combining all the skills required) pre-training gave the best indication of post-training scanning performance. The Obstetric Structured Assessment Test may prove a useful tool for initial assessment of potential trainees but abilities will require further investigation.
Generational dynamics in Spain: Memory transmission of a turbulent past
Authors: Aguilar Paloma , Ramírez-Barat Clara
Published: October 2016

Despite the crucial transformations that Spain has experienced since Franco’s death, and in contrast with other countries that have democratized in recent decades, considerable reluctance remains toward implementing transitional justice measures. On the contrary, there is a tendency to hold on to a framework that combines the Amnesty Law of 1977 with partial reparations as the best guarantors of democratic stability. According to extant literature, generational change has played a fundamental role in the direction taken by recent initiatives dealing with the memory of Francoist repression, particularly since 2000. A small but very active part of the “grandchildren’s generation” has driven various initiatives that have influenced political and judicial agendas. We provide empirical evidence showing that while, in general terms, it would be true to say that third and fourth generations have been more supportive of the implementation of bolder memory policies, their contribution must nevertheless be subjected to careful nuancing.
Prospective multicentre study in intensive care units in five cities from the Kingdom of Saudi Arabia: Impact of the International Nosocomial Infection Control Consortium (INICC) multidimensional approach on rates of central line-associated bloodstream infection
Authors: Al-Abdely Hail M , Alshehri Areej Dhafer , Rosenthal Victor Daniel , Mohammed Yassir Khidir , Banjar Weam , Orellano Pablo Wenceslao , Assiri Abdullah Mufareh , Kader Nahla Moustafa Abedel , Enizy Hessa Abdullah Al , Mohammed Diaa Abdullah , Al-Awadi Duaa Khalil , Cabato Analen Fabros , Wasbourne Maria , Saliya Randa , Aromin Rosita Gasmin , Ubalde Evangelina Balon , Diab Hanan Hanafy , Alkamaly Modhi Abdullah , Alanazi Nawal Mohammed , Hassan Assiry Ibtesam Yahia , Molano Apsia Musa , Flores Baldonado Celia , Al-Azhary Mohamed , Al Atawi Sharifa , Molano Apsia Musa , Al Adwani Fatima Mohammad , Casuyon Pahilanga Arlu Marie , Nakhla Raslan , Al Adwani Fatma Mohammad , Nair Deepa Sasithran , Sindayen Grace , Malificio Annalyn Amor , Helali Najla Jameel , Al Dossari Haya Barjas , Kelany Ashraf , Algethami Abdulmajid Ghowaizi , Yanne Leigh , Tan Avigail , Babu Sheema , Abduljabbar Shatha Mohammad , Bukhari Syed Zahid , Basri Roaa Hasan , Mushtaq Jeyashri Jaji , Rushdi Hala , Turkistani Abdullah Abdulaziz , Gonzales Celiz Jerlie Mae , Al Raey Mohammed Abdullah , Al-Zaydani Asiri Ibrahim AM , Aldarani Saeed Ali , Laungayan Cortez Elizabeth , Demaisip Nadia Lynette , Aziz Misbah Rehman , Omer Abdul Aziz Ali , Al Manea Batool , Samy Eslam , Al-Dalaton Mervat , Alaliany Mohammed Jkedeb
Published: October 2016

Objective:

To analyse the impact of the International Nosocomial Infection Control Consortium (INICC) Multidimensional Approach (IMA) and INICC Surveillance Online System (ISOS) on central line-associated bloodstream infection (CLABSI) rates in five intensive care units (ICUs) from October 2013 to September 2015.

Design:

Prospective, before-after surveillance study of 3769 patients hospitalised in four adult ICUs and one paediatric ICU in five hospitals in five cities. During baseline, we performed outcome and process surveillance of CLABSI applying CDC/NHSN definitions. During intervention, we implemented IMA and ISOS, which included: (1) a bundle of infection prevention practice interventions; (2) education; (3) outcome surveillance; (4) process surveillance; (5) feedback on CLABSI rates and consequences; and (6) performance feedback of process surveillance. Bivariate and multivariate regression analyses were performed.

Results:

During baseline, 4468 central line (CL) days and 31 CLABSIs were recorded, accounting for 6.9 CLABSIs per 1000 CL-days. During intervention, 12,027 CL-days and 37 CLABSIs were recorded, accounting for 3.1 CLABSIs per 1000 CL-days. The CLABSI rate was reduced by 56% (incidence-density rate, 0.44; 95% confidence interval, 0.28–0.72; P = 0.001).

Conclusions:

Implementing IMA through ISOS was associated with a significant reduction in the CLABSI rate in the ICUs of Saudi Arabia.
Health promotion and knowledge translation: two roads to the same destination?
Authors: Paterson Maeve , Lagosky Stephanie , Mason Robin
Published: October 2016

Health Promotion (HP), a continuously evolving field, is riddled with complexities as experts and community members develop new approaches to researching social behaviours, addressing health concerns and advocating for the values of equity, empowerment and healthy public policy. Similarly complex is the field of knowledge translation (KT), putting research into action for the purpose of changing behaviours, policy and practice. Similar values, methods and techniques govern these two practices. This paper is based on a series of discussions between two young professionals who found themselves navigating the complexities of HP and KT and attempting to understand their chosen fields of practice. The discussions considered such issues as discipline-based silos, the use and purpose of new terminologies and languages in research, and whether or not existing practices are simply being renamed or branded in order to appear innovative and new.
When Does Men’s Hostile Sexism Predict Relationship Aggression? The Moderating Role of Partner Commitment
Authors: Cross Emily J. , Overall Nickola C. , Hammond Matthew D. , Fletcher Garth J. O.
Published: October 2016

Hostile sexism encompasses aggressive attitudes toward women who contest men’s power and suspicions that women will manipulate men by exploiting their relational dependence. Prior research has shown that these attitudes predict greater aggression toward female relationship partners, but has overlooked the contexts in which such aggression should occur. The present research identified an important contextual factor that determines when men’s hostile sexism is (and when it is not) associated with relationship aggression. Men who more strongly endorsed hostile sexism were more aggressive toward their female partners during couples’ daily life (Study 1) and conflict discussions (Study 2), but only when their female partners were perceived to be, or reported being, low in relationship commitment. These findings show that men who endorse hostile sexism do not always enact aggression toward female partners, but do so in contexts relevant to their fears that women will exploit men’s relational dependence and undermine men’s power.
Mepolizumab for severe refractory eosinophilic asthma: evidence to date and clinical potential
Authors: Menzella Francesco , Lusuardi Mirco , Galeone Carla , Taddei Sofia , Facciolongo Nicola , Zucchi Luigi
Published: October 2016

Severe asthma is characterized by major impairment of quality of life, poor symptom control and frequent exacerbations. Inflammatory, clinical and causative factors identify different phenotypes and endotypes of asthma. In the last few years, new treatment options have allowed for targeted treatments according to the different phenotypes of the disease. To accurately select a specific treatment for each asthmatic variant, the identification of appropriate biomarkers is required. Eosinophilic asthma is a distinct phenotype characterized by thickening of the basement membrane and corticosteroid responsiveness. This review reports the latest evidence on an anti-IL-5 monoclonal antibody, mepolizumab, a new and promising biological agent recently approved by the FDA specifically for the treatment of severe eosinophilic refractory asthma.
The Time-Course of Ultrarapid Categorization: The Influence of Scene Congruency and Top-Down Processing
Authors: Vanmarcke Steven , Calders Filip , Wagemans Johan
Published: October 2016

Although categorization can take place at different levels of abstraction, classic studies on semantic labeling identified the basic level, for example, dog, as entry point for categorization. Ultrarapid categorization tasks have contradicted these findings, indicating that participants are faster at detecting superordinate-level information, for example, animal, in a complex visual image. We argue that both seemingly contradictive findings can be reconciled within the framework of parallel distributed processing and its successor Leabra (Local, Error-driven and Associative, Biologically Realistic Algorithm). The current study aimed at verifying this prediction in an ultrarapid categorization task with a dynamically changing presentation time (PT) for each briefly presented object, followed by a perceptual mask. Furthermore, we manipulated two defining task variables: level of categorization (basic vs. superordinate categorization) and object presentation mode (object-in-isolation vs. object-in-context). In contradiction with previous ultrarapid categorization research, focusing on reaction time, we used accuracy as our main dependent variable. Results indicated a consistent superordinate processing advantage, coinciding with an overall improvement in performance with longer PT and a significantly more accurate detection of objects in isolation, compared with objects in context, at lower stimulus PT. This contextual disadvantage disappeared when PT increased, indicating that figure-ground separation with recurrent processing is vital for meaningful contextual processing to occur.
Revisiting the internal consistency and factorial validity of the 8-item Morisky Medication Adherence Scale
Authors: Zongo Arsène , Guénette Line , Moisan Jocelyne , Guillaumie Laurence , Lauzier Sophie , Grégoire Jean-Pierre
Published: October 2016

Objective:

To assess the internal consistency and factorial validity of the adapted French 8-item Morisky Medication Adherence Scale in assessing adherence to noninsulin antidiabetic drug treatment.

Study Design and Setting:

In a cross-sectional web survey of individuals with type 2 diabetes of the Canadian province of Quebec, self-reported adherence to the antidiabetes drug treatment was measured using the Morisky Medication Adherence Scale-8. We assessed the internal consistency of the Morisky Medication Adherence Scale-8 with Cronbach’s alpha, and factorial validity was assessed by identifying the underlying factors using exploratory factor analyses.

Results:

A total of 901 individuals completed the survey. Cronbach’s alpha was 0.60. Two factors were identified. One factor comprised five items: stopping medication when diabetes is under control, stopping when feeling worse, feeling hassled about sticking to the prescription, reasons other than forgetting and a cross-loading item (i.e. taking drugs the day before). The second factor comprised three other items that were all related to forgetfulness in addition to the cross-loading item.

Conclusion:

Cronbach’s alpha of the adapted French Morisky Medication Adherence Scale-8 was below the acceptable value of 0.70. This observed low internal consistency of the scale is probably related to the causal nature of the items of the scale but not necessarily a lack of reliability. The results suggest that the adapted French Morisky Medication Adherence Scale-8 is a two-factor scale assessing intentional (first factor) and unintentional (second factor) non-adherence to the noninsulin antidiabetes drug treatment. The scale could be used to separately identify these outcomes using scores obtained on each of the sub-scales.
Experiences of hand hygiene among acute care nurses: An interpretative phenomenological analysis
Authors: Chatfield Sheryl L , Nolan Rachael , Crawford Hannah , Hallam Jeffrey S
Published: October 2016

Objective:

Occurrences of healthcare-associated infections are associated with substantial direct and indirect costs. Improvement in hand hygiene among acute care nurses has potential to reduce incidence of healthcare-associated infections. Findings from reviews of intervention research have not conclusively identified components that are more or less efficient or effective. Much prior qualitative research has focused on descriptive analysis of policies and practices rather than providing interpretive explorations of how individuals’ perceptions of hygiene might drive practices.

Methods:

We conducted qualitative interview research with eight nurses in the United States who were employed in various patient-care roles. We analyzed the data using an interpretative phenomenological analysis methodology to explore how nurses described their perceptions of, and experiences with, hygiene. We developed themes that explored individual, workplace, and management influences on perception of hygiene.

Results:

Developed themes include practical hygiene, risky business, and hygiene on trial; the latter theme described the conflict between how nurses perceived their own hygiene practices and how they felt hospital management perceived these practices. Other findings included that participants distinguished between policy-mandated use of sanitizer and a personal sense of cleanliness; the latter was more likely to be associated with scrubbing or removal of contaminants than with use of protectants.

Conclusion:

While participants asserted support for facility hand hygiene policies, their behavior in certain instances might be mediated by broadly defined emergent situations and a belief that it is not currently possible to establish a causal link between an healthcare-associated infections and a specific individual or occurrence. Researchers and infection prevention practitioners might consider soliciting greater input from nurses in planning hand hygiene improvement interventions, to encourage ownership, and emphasizing detailed cases as training content to take advantage of individuals’ sensory responses to hygiene.
Delayed onset of a spinal epidural hematoma after facet joint injection
Authors: Velickovic Mirko , Ballhause Tobias M
Published: October 2016

The treatment of chronic back pain is a challenging problem. Facet joint infiltration is an established treatment for chronic low back pain caused by arthrosis of the lumbar facet joints. Due to the increasing number of patients with chronic low back pain, this therapy has become more frequent. We treated a 51-year-old male patient, who developed an epidural hematoma 2 months after infiltration therapy. Our case shows that even a delayed onset of spinal epidural hematoma is possible and should be kept in mind as a possible cause of acute myelopathy after spinal intervention.
A Preliminary Study of Genetic Variation in the Dopaminergic and Serotonergic Systems and Genome-Wide Additive Genetic Effects on Depression Severity and Treatment Response
Authors: Palmer Rohan H. C. , Beevers Christopher G. , McGeary John E. , Brick Leslie A. , Knopik Valerie S.
Published: October 2016

Major depression is a heritable disorder that is commonly treated with selective serotonin reuptake inhibitors. However, no study has quantified the overlap in genetic effects between pretreatment depression severity and treatment response and the extent to which genetic effects could be attributed to variation in the dopaminergic and serotonergic systems (DA/5-HT). Data (N=1618) from the clinician-rated Hamilton Rating Scale of Depression and the clinician-rated Quick Inventory of Depressive Symptomatology were obtained from participants of European ancestry in the Sequenced Treatment Alternatives to Relieve Depression clinical trial. Genetic variants explained 31%–64% of the variance across assessments of pretreatment depression severity and treatment response. However, effects from the DA/5-HT systems genes were negligible. There was also limited evidence for genetic overlap for pretreatment depression severity and treatment response. Despite the clear genetic contributions to these depression phenotypes, different genetic factors may contribute to depression severity and treatment response.
Effect of pH on the cation exchange capacity of some halloysite nanotubes
Authors: Gray Nia , Lumsdon David G. , Hillier Stephen
Published: October 2016

The cation exchange capacity (CEC) of seven well characterized halloysite nanotubes (HNTs) in the dehydrated 7 Å form has been measured using a method based on cobalt hexammine exchange. In addition to unbuffered measurements, which varied between 2.9 and 9.3 cmol(+)kg−1, CECs were also determined over a wide pH range and proton titration measurements were conducted on two samples. The data were fitted using a constant capacitance model based on the presence of two sites: permanently charged sites and pH-dependent variable charged sites. Normalization of CEC to the average specific surface area (BET) of the halloysite samples reduces considerably the variation of CEC values for the different samples particularly over the intermediate pH range (5–9) with the average value at pH 7 equal to 8.5 cmol(+)kg−1and a standard deviation of 1.17. Overall the CEC behaviour of the seven samples appears reasonably consistent throughout the set. Calculations based on proton titrations suggest a ratio of variable charge to basal sites for the dehydrated halloysite nanotubes of ∼3:1.
Biodegradable polymer nanocomposites based on natural nanotubes: effect of magnetically modified halloysite on the behaviour of polycaprolactone
Authors: Khunová Viera , Šafařík Ivo , Škrátek Martin , Kelnar Ivan , Tomanová Katarína
Published: October 2016

The present study explores the effect of a magnetically modified halloysite (mHNT) surface on the structure and properties of biodegradable polymer nanocomposites based on poly ɛ-caprolactone (PCL). Halloysite nanotubes (HNTs) have been modified by a scalable and tunable procedure using magnetic Fe oxide particles prepared by microwave-assisted synthesis fromferrous sulfate at high pH. The HNT content in composites prepared in melt varied from 5 to 30 wt.%. Application of magnetically modified HNT to PCL resulted in the formation of soft magnetic materials. Analyses of the nanocomposite structure revealed that both natural and magnetized HNTs, as well as free magnetite particles are dispersed uniformly in the polymer matrix. Investigation of the mechanical and physical properties confirmed that the reinforcing ability of HNTs was not affected by magnetic modification.
Halloysite nanotubes: prospects and challenges of their use as additives and carriers – A focused review
Authors: Pasbakhsh Pooria , De Silva Rangika , Vahedi Vahdat , Jock Churchman G.
Published: October 2016

There is increasing research interest in potential applications of halloysite as fillers for polymer composites, controlled drug delivery, carriers for the supply and sustained release of active agents for anticorrosion coatings, in nanoreactors or nanotemplates, and for the uptake of contaminants or pollutants and support for catalysts. In this review, recent findings in terms of the prospects and challenges of using halloysite nanotubes (HNTs) in different polymeric matrices targeting a range of old and new applications are discussed and evaluated. The compositions include chitosan/halloysite membranes as bone-tissue scaffolds, polylactic acid (PLA)/halloysite membranes for food-packaging applications and their antimicrobial activities, instrumented impact properties of epoxy/halloysite nanocomposites and the role of halloysite in the self-healing of epoxy composites, polyacryronitrile (PAN)/halloysite membranes for use in water filtration as well as a review of some recent applications of halloysite/alginate beads in the adsorption of contaminants such as lead.