bluuebunny/crossref_metadata_2025 huggingface dataset:
SOSIALISASI PENCEGAHAN PENYALAHGUNAAN NARKOTIKA DI KALANGAN REMAJA SMA NEGERI 1 CIRUAS
Authors: Rokilah Rokilah
Published: November 2024

Penyalahgunaan narkotika dan obat-obatan terlarang di kalangan generasi muda dewasa ini kian meningkat Maraknya penyimpangan perilaku generasi muda tersebut, dapat membahayakan keberlangsungan hidup bangsa ini di kemudian hari. Karena generasi muda sebagai generasi yang diharapkan menjadi penerus bangsa, semakin hari semakin rapuh digerogoti zat-zat adiktif penghancur syaraf. Sehingga generasi muda tersebut tidak dapat berpikir jernih. Akibatnya, generasi harapan bangsa yang tangguh dan cerdas hanya akan tinggal kenangan. Sasaran dari penyebaran narkotika ini adalah kaum muda atau remaja. Kalau dirata-ratakan, usia sasaran narkotika ini adalah usia pelajar. Tujuan dari kegiatan sosialisasi dan penyuluhan ini adalah agar masyarakat khususnya siswa di SMA Negeri 1 Ciruas, mendapatkan pemahaman tentang pengertian narkotika, golongan narkotika dan bahaya dari penyalahgunaan narkotika agar tidak terjerumus dalam tindak pidana narkotika.
Peran Strategis Pendidikan dalam Mengembangkan Jiwa Ecopreneur di Kalangan Pelajar Sekolah Menengah Atas
Authors: Nafiudin Nafiudin , Ripaldi Ugi , Rangga  , Maddah Ghina Laila
Published: November 2024

Minat wirausaha di kalangan pelajar sekolah menengah atas di Indonesia masih rendah ini disebabkan oleh berbagai faktor, seperti keyakinan bahwa menjadi karyawan lebih baik daripada berwirausaha serta kurangnya motivasi dan efikasi diri untuk memulai usaha mandiri, dan disisi lain bahwa Indonesia menjadi negara peringkat kedua sebagai penyumbang sampah plastik ke laut di Dunia, berada satu posisi dibawah China sebagai peringkat pertamanya. Dan tujuan dari kegiatan pengabdian masyarakat ini adalah meningkatkan minat berwirausaha dengan konsep ramah lingkungan, Adapun metode pengabdian masyarakat yang dilakukan melalui kegiatan Pendidikan kewirausahaan ramah lingkungan dan berdasarkan hasil pengabdian bahwa minat dan wawasan Gaya Hidup Berkelanjutan dan berwirausaha di kalangan pelajar siswa tingkat menengah atas mengalami peningkatan.
Pemanfaatan Teknologi Informasi Dan Strategi Pemasaran pada Usaha Mikro Kecil Menengah Berbasis Kekayaan Intelektual Di Desa Mesjid Priyayi Kecamatan Kasemen
Authors: Sulasno Sulasno , Fauzan Nuno M , Fadhiila Z Afkaar , Malika N Lika , Nap Eka , Masnah Y Ambar
Published: November 2024

Kekurangpahaman masyarakat Desa Mesjid Priyayi terkait dengan teknologi informasi dan kekayaan intelektual perlu mendapatkan perhatian yang serius dari berbagai pihak utamanya dari pihak pemerintahan Kota Serang. Salah satunya berkaitan dengan pemanfaatan produk produk usaha mikro, kecil, dan menengah merupakan salah satu upaya strategis dalam menggerakkan perekonomian lokal serta mendorong kemandirian ekonomi masyarakat. Di tengah persaingan global dan dinamika pasar semakin kompleks, kualitas produk menjadi hal yang sangat penting yang dapat mempengaruhi daya saing UMKM. Pelaksanaan pengabdian masyarakat ini bertujuan untuk meningkatkan pemanfaatan strategi pemasaran dan teknologi informasi pada usaha mikro kecil menengah produk Kue Satu dan Gipang yang berlokasi di Kampung Magelaran Cilik, Desa Mesjid Priyayi, Kecamatan Kasemen. Metode pelaksanaan yang digunakan dalam pengabdian ini meliputi survei lapangan dan pelatihan digital marketing kepada pemilik UMKM Kue Satu dan Gipang. Survei lapangan dilakukan untuk mengidentifikasi permasalahan, tantangan dan potensi yang dimiliki oleh UMKM kue satu dan gipang dalam meningkatkan kredibilitas produk mereka. Adapun hasil pengabdian ini menunjukkan bahwa pemahaman yang lebih baik mengenai manajemen produksi, pengembangan kekayaan intelektual (merek, cipta, paten. desain industri, rahasia dagang. DTLST) dan strategi pemasaran memberikan dampak positif terhadap kualitas produk dan persepsi pelanggan terhadap kualitas produk UMKM kue satu dan gipang. Melalui pendampingan intensif, UMKM kue satu dan gipang mampu meningkatkan dan menyejahterakan perekonomian masyarakat setempat.
Home Language and Philosophers’ Language
Authors: Hertzberg Lars
Published: November 2024

This paper investigates whether Wittgenstein can be considered an ‘ordinary language philosopher’. A central role in his thinking is that of what may be called our ‘home language’ - the language we bring along in coming to do philosophy. The intelligibility of philosophers’ language depends on its relation to the home language. This is the central point of Philosophical Investigations § 116. Traditional philosophical ‘uses’ of a word like ‘knowledge’ have a problematic relation to our customary uses of the word. In consequence, traditional philosophers have sometimes lost the grip on how such words are actually used in human interaction.
“Following according to a rule is FUNDAMENTAL to our language-game”. Rules and Meaning in Wittgenstein
Authors: Child William
Published: November 2024

There is widespread agreement that, in his later philosophy, Wittgenstein sees the meaning of a word as a matter of the rules for its use; to grasp its meaning is to grasp the rules for its use; and using the word with that meaning is a matter of following those rules. Kathrin Glüer and Åsa Wikforss have challenged that widely-shared interpretation. They argue that the later Wittgenstein does not think that the meanings of words are determined by rules or that using language involves following rules. And they think that the idea that using a word involves following rules is not just wrong as an interpretation of Wittgenstein; it is philosophically unacceptable in its own right.  The paper defends the standard interpretation of Wittgenstein on rules and meaning against Glüer and Wikforss’s arguments. Textual evidence in favour of the standard interpretation is presented.  Glüer and Wikforss’s textual case for their interpretation is discussed and found unconvincing. The paper then defends the view that using language involves following rules against Glüer and Wikforss’s philosophical critique. It is argued that Wittgenstein shows us a way to understand language-use as a form of rule-following behaviour that is consistent with his other commitments and maintains the distinction between following a rule and merely acting in accord with a rule. His account is an anti-reductionist one; there is no prospect of giving a non-circular account of what it is to follow a rule. But there is nothing philosophically unsatisfactory about that.
Frege and Wittgenstein’s Later Philosophy
Authors: McGinn Marie
Published: November 2024

Interpreters have tended to focus on the relation between Frege and the early Wittgenstein, but Frege also posed problems for the later Wittgenstein. Wittgenstein's concept of a language-game was inspired byHilbert's alleged formalism, as criticised by Frege, and it points to an important dialogue that Wittgenstein engages in with Frege. Wittgenstein expresses formalist views and invokes Frege's critique of formalism at the beginning of the Big Typescript and The Blue Book. He engages more deeply with the problems posed by Frege and formalism in the remarks collected in Philosophical Grammar,where the issues raised set the agenda for the first §§242 of the Philosophical Investigations. The radical transformation in our understanding of meaning and understanding that takes place enables Wittgenstein to escape the problems which P.T. Geach believes were posed for him by Frege's paper "Thought", concerning first-person thoughts about sensations.
Sinodalità e primato nel pontificato di papa Francesco
Authors: Faggioli Massimo
Published: November 2024

Pope Francis has undoubtedly not only received into the papal magisterium, but also made the recovery of ecclesial synodality as an evolution of the ecclesiology of Vatican II a central part of the agenda of his pontificate. At the same time, this recovery of synodality goes together, in the theology and practice of government of Pope Francis, with a notion and exercise of a strong papal primacy, and occurs in a moment of redefinition, in practice, of the criteria of the unity of Catholicism as global Catholicism, in a communion of churches that are increasingly different from each other. The relationship between synodality and primacy, as it unfolded in the first eleven years of Francis’ pontificate, leaves many questions open on the outcomes of the ‘synodal process’ (2021‑24) in the medium and long term, as well as on the forms that the exercise of the papal primacy will assume.
Francis’ Papacy Analyzed from a Historical Perspective
A Catholicism for the Twenty-First Century?
Authors: Mauro Diego
Published: November 2024

In this article I analyze the main innovations of Francis' papacy from the point of view of the history of contemporary Catholicism, both in the field of social doctrine and in the government of the Church. Secondly, I study his political strategies, which I define as “inverted gatopardism.” In my opinion, these strategies have helped Bergoglio control the opposition of traditionalist and conservative sectors, as well as internal tensions.
Papa Francesco e il cattolicesimo in Germania
Da ultimo una grande delusione?
Authors: Kruip Gerhard
Published: November 2024

The article provides an overview of the reception of Pope Francis in Germany following his election in 2013. The initial euphoric reactions are understandable, as Francis raised high expectations, particularly with Evangelii gaudium, regarding the resolution of the enormous backlog of reforms in the Catholic Church in Germany, whose religious situation differs significantly from that of other countries. However, since the post-synodal letter Querida Amazonía, disappointment with Francis has predominated. In particular, the Vatican’s reactions to the ‘Synodal Path’ have caused irritation.
Prospettive dell’ecumenismo nel XXI secolo
Authors: Ferrario Fulvio
Published: November 2024

After providing an overview of the achievements of twentieth-century ecumenical dialogue, the article outlines a number of problematic issues currently on the agenda: the state of theological dialogues; ‘intercultural’ ecumenism; Christian ecumenism in the face of so-called global challenges (in particular, justice, peace, and the safeguarding of creation); and short- and medium-term prospects, as envisaged from the most recent developments.
Intususcepción yeyuno-yeyunal causada por linfoma difuso de células B grandes ALK positivo. Reporte de caso
Authors: Dagnesses-Fonseca Javier O. , Donat-Garrido María , Calvo-Espino Pablo , Pérez-Morera Adelino Patricio
Published: November 2024

Introducción. La intususcepción en adultos es una afección poco frecuente, a menudo causada por tumores del tracto gastrointestinal. Su presentación clínica es atípica, lo que dificulta y retrasa el diagnóstico. Existen pocos casos reportados en la literatura de intususcepción en adultos secundaria a linfomas.
Caso clínico. Se presenta el caso de un hombre en la quinta década de la vida, que consultó por síntomas inespecíficos de astenia, pérdida de peso, febrícula y anemia secundaria a sangrado digestivo oculto.
Resultados. Los hallazgos en los estudios imagenológicos revelaron una intususcepción yeyuno-yeyunal, que posteriormente fue confirmada durante la cirugía, donde como causa de la invaginación se encontró una tumoración probablemente maligna. El análisis patológico y la inmunohistoquímica identificaron un linfoma difuso de células B grandes ALK positivo. La intususcepción en adultos suele estar relacionada con tumores del tracto gastrointestinal, siendo los linfomas una causa poco frecuente. Un diagnóstico y tratamiento precoz son claves para evitar complicaciones y mejorar los resultados clínicos.
Conclusiones. La afectación por linfoma del tubo digestivo es causa de intususcepción en el adulto. Los síntomas son inespecíficos, por lo que se suele retrasar el diagnóstico, y esto puede llevar a complicaciones graves como obstrucción intestinal, con un peor pronóstico para el paciente. La cirugía es el tratamiento principal para la invaginación, seguida de quimioterapia para el linfoma. Es crucial la exploración del intestino durante la cirugía y la identificación del tipo de linfoma mediante el análisis patológico para orientar el tratamiento posterior.
INDONESIAN FISHERIES AND SPICES COMMODITIES IN THE UNITED STATES AND THE EUROPEAN UNION: RSCA AND URR ANALYSIS
Authors: Sukarniati Lestari , Rahmi Mustika
Published: November 2024

Although Indonesia has potential in fisheries and spice commodities, Indonesia also faces challenges where food commodities including fisheries and Indonesian spices often experience rejection, especially from the United States and the European Union. On the other hand, with its potential, Indonesian fisheries and spices products are expected to have comparative advantages that result in improved quality of goods and services so as to provide higher competitiveness in international trade. This study aims to determine how the competitiveness and trade conditions of fishery commodities and spices from Indonesia to the United States and the European Union from 2015-2022. The analytical tools used in this study are Revelaed Symetric Comparative Advantage (RSCA) and Trade Specialization index (ISP) to analyze competitiveness while to analyze the reasons for rejection and its relation to the food quality of these commodities the Unit Rejection Rate (URR) analysis is used. From the research results, it was found that all Indonesian fishery and spice products traded to the United States and the European Union have a comparative advantage both in 2015 and in 2022 because they have an RSCA score above 0. While the URR value of Indonesian fishery and spice commodities to the United States and the European Union has also decreased, which means that the number of rejections is decreasing, and the quality of food quality is increasing.
Features of structure formation of coatings during thermohydrochemical treatment of steel tool
Authors:   Belarusian National Technical University, Minsk, 220013, Shmatov A. A. ,   Wuhan Textile University, Wuhan, 430073, China, Soos L. ,   Slovak University of Technology, Bratislava, 81107, Slovakia, Krajny Z. ,   Slovak University of Technology, Bratislava, 81107, Slovakia
Published: November 2024

В работе изучены вопросы структурообразования покрытий, полученных термогидрохимической обработкой (ТГХО), которая позволяет увеличить в 1,4—8 раз стойкость стальных инструментов, по сравнению с традиционными. ТГХО включает: 1) гидрохимическую обработку (ГХО) инструмента в кипящей гидрозоли керамических материалов для осаждения твердосмазочных покрытий; 2) термообработку (ТО). Установлено, что при ГХО стали формируются покрытия с нанокристаллической структурой, а при нагреве выше 500 °С — с нанокомпозитной. Предложена модель-схема поэтапного формирования покрытий при ТГХО стального инструмента, включающая гидрохимическое (ГХ) получение нанопокрытий в водной дисперсионной среде, основанное на образовании в ней полярных мицелл на базе керамических наночастиц в условиях расклинивающего действия поверхностно-активных веществ (ПАВ), электрохимического и ударно-импульсного термогидродинамического воздействия кипящей водной дисперсионной среды, дальнейшего переноса и разрядки мицелл на стальной поверхности с осаждением твердых мономолекулярных слоев, затем проведение термической обработки. Ключевые слова: термогидрохимическая обработка, твердосмазочное покрытие, стальной инструмент.
Probabilidad de ocurrencia de temperaturas máximas y mínimas medias decádicas en Inta Paraná y zona de influencia (Entre Ríos, Argentina)
Authors: Brizuela A. B. , Saluso J. H.
Published: November 2024

La producción agropecuaria depende en gran medida del comportamiento de las variables meteorológicas durante el ciclo productivo. Sin embargo ese comportamiento, aunque aleatorio, responde a ciertos modelos probabilísticos como es el caso de las temperaturas máximas y mínimas diarias. En este trabajo se prueba la hipótesis de normalidad y se muestra una técnica de estimación de intervalos de confianza de los valores medios decádicos de las temperaturas máximas y mínimas en diferentes momentos del año.
Sistemas agrícolas sugeridos y riesgos climáticos asociados en la provincia de Córdoba (Argentina)
Authors: De la Casa A. C. , Rodríguez A. R.
Published: November 2024

A partir de variables agroclimáticas específicas de los sistemas productivos de secano, son clasificados distintos ambientes de la Provincia de Córdoba en zonas agronómicamente homogéneas. Con los datos meteorológicos diarios de 6 localidades del período 1968-87, se obtuvo información sobre los sistemas de producción mejor adaptados, como así también las prácticas más convenientes y oportunas, sugeridas de acuerdo al riesgo climático que presenta la actividad agrícola. Es utilizada la técnica de analogías agroclimáticas para analizar la potencialidad de las distintas localidades. Los resultados ponen de manifiesto un adecuado ajuste de la metodología clasificatoria, a pesar de haberse aplicado fuera de la región semiárida tropical de origen. Son detectadas tres zonas agroclimáticas que incluyen: la primera a Villa Dolores, la segunda a Pilar, Río Cuarto y Laboulaye, y la restante a Marcos Juárez y Villa de María de Río Seco. La inclusión de restricciones de naturaleza térmica (período con heladas),con el objeto de extender el esquema de clasificación a regiones agrícolas de climas templados, sólo modifica en Laboulaye la propuesta original. A las sugerencias de aprovechamiento sobre un eventual atraso en la época de siembra, se les debe asignar un nivel de riesgo que integre los factores hídrico y térmico limitantes.
Aspectos agrohidrológicos de los cultivos de tomate y poroto en Orán (Salta), Argentina
Authors: Falasca S. , Zabala S. M. , Forte Lay J. A.
Published: November 2024

El objetivo del presente trabajo es el de evaluar el manejo de los cultivos de tomate primicia y de poroto seco para la exportación en Orán, mediante un balance hidrológico diario, en relación a las necesidades de riego complementario pasadas y presentes. Con los datos pluviométricos de la localidad de Orán se confeccionaron tres balances hidrológicos diarios simulando diferentes manejos del suelo: pastura natural, abono verde - cultivo de tomate y abono verde - cultivo de poroto. Posteriormente se analizó la serie obtenida de almacenajes de agua edáfica y se calculó la probabilidad de sequía absoluta, sequía condicional y humedad óptima para cada década del año. Por último, se estudió para el período crítico y para todo el ciclo del cultivo, la posibilidad de aplicación de riego complementario. El seguimiento de los almacenajes medios simulados mostró que la frecuencia de sequías, para justificar la aplicación de riego, fue mayor a mediados que a principios del presente siglo, cosa que no sucede desde las últimas décadas, debido al incremento que han sufrido las precipitaciones pluviales.
Board Performance of Fisheries Graduates: Logistic Regression Analysis for Curriculum Enhancement
Authors: Matusalem Nora M , Bandoy Marcial M , Buama Chester Alexis C , Manaig Karen A , Yazon Alberto D
Published: November 2024

This study investigates the factors affecting the board performance of Bachelor of Science in Fisheries (BSFi) graduates in the fisheries technologists licensure exams in a specific region of the Philippines. The impetus for this research arose from observed variations in exam performance among graduates, prompting an examination of educational and institutional influences on success. The study used a purposive sampling technique to gather data from 138 respondents across State Universities and Colleges (SUCs) who took their first licensure exam from October 2018 to October 2023. A validated online survey questionnaire assessed academic performance, teaching methods, curriculum, faculty qualifications, library resources, laboratory facilities, and student characteristics. Logistic regression analysis was employed to analyze the relationship between these independent variables and licensure exam performance. The findings of this study are of profound importance, as they reveal strong correlations between faculty qualifications and exam outcomes, emphasizing the need for continuous professional development. Moreover, the study identifies improved laboratory facilities and a robust curriculum as critical factors contributing to student success. These insights have the potential to significantly impact stakeholders, informing them about essential areas for intervention and improvement. Ultimately, they aim to elevate the educational experience and licensure performance of BSFi graduates, thus supporting their professional trajectories in the fisheries sector.
DYNAMICS OF THE NUMBER OF FLOWERS PER INFLORESCENCE IN A RARE SPECIES OXYTROPIS HIPPOLYTI IN THE NATURAL POPULATION IN THE VICINITY OF MOUNT GUROVSKAYA (BASHKIR CIS-URALS) (2016 2018)
Authors:   Bashkir State Pedagogical University named after M. Akmully, Ufa, Russia, Khalitova N.M. , Egorova А.А. ,   Bashkir State Pedagogical University named after M. Akmully, Ufa, Russia
Published: November 2024

The article presents data on the variability of the number of flowers in an inflorescence in a rare endemic species Oxytropis hippolyti Boriss. (family Fabaceae) in a natural population in the vicinity of Mount Gurovskaya in the Kushnarenkovsky district of the Republic of Bashkortostan (RB). This species is included in The Red Data Book of the RB [2021]. There was a decrease in the limit values (from 7-50 pcs. to 3-35 pcs.) and average values (from 27 pcs. to 15 pcs.) of the number of flowers in the inflorescence between 2016 and 2018. The frequency of occurrence of inflorescences based on the number of flowers varies according to the years of observation. The inflorescences with the number of flowers of two classes are most common: 11-20 pieces (this class predominated prevailed in 2018 – 66.7 %) and 21-30 pcs. (this class prevailed in 2016 and 2017 – 56.0 and 49.5 %, respectively). The variability of the number of flowers in samples by years of observations was characterized by an increased (CV=21-30 %) and high (CV=31-40 %) level, intra-population and year-by-year variability – by an increased level.
STUDY OF HEPATOTOXIC EFFECT OF ALUMINUM HYDROXIDE INTRODUCED INTO THE GASTROINTESTINAL TRACT OF RATS IN A SUBACUTE EXPERIMENT
Authors:   Ufa Research Institute of Occupational Medicine and Human Ecology, Ufa, Russia, Smolyankin D.A. , Gizatullina A.A. ,   Ufa Research Institute of Occupational Medicine and Human Ecology, Ufa, Russia, Yakupova T.G. ,   Ufa Research Institute of Occupational Medicine and Human Ecology, Ufa, Russia, Valova Ya.V. ,   Ufa Research Institute of Occupational Medicine and Human Ecology, Ufa, Russia, Akhmadeev A.R. ,   Ufa Research Institute of Occupational Medicine and Human Ecology, Ufa, Russia, Karimov D.O. ,   Ufa Research Institute of Occupational Medicine and Human Ecology, Ufa, Russia,   N.A. Semashko National Research Institute of Public Health, Moscow, Russia, Ryabova Yu.V. ,   Ufa Research Institute of Occupational Medicine and Human Ecology, Ufa, Russia, Repina E.F. ,   Ufa Research Institute of Occupational Medicine and Human Ecology, Ufa, Russia, Usmanova E.N. ,   Ufa Research Institute of Occupational Medicine and Human Ecology, Ufa, Russia, Kudoyarov E.R. ,   Ufa Research Institute of Occupational Medicine and Human Ecology, Ufa, Russia
Published: November 2024

Aluminum (Al) has various toxic effects on biosystems. Essential properties of aluminum have not been established, the mechanisms of impairment are insufficiently studied. The negative impact of aluminum on the human body leads to liver damage, increased oxidative stress and development of hepatotoxicity. Blood enzymes are characteristic markers of liver function and are used to assess the toxicity of environmental pollutants. The aim of the study was to investigate the activity of enzyme markers of hepatotoxicity, aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) in the blood of laboratory animals after subacute intoxication with aluminum hydroxide (Al(OH)3). The experiment was conducted on 80 white rats divided into 4 groups. Three groups of animals orally received Al(OH)3 solution of different concentrations for a month, the control group was administered distilled water. At the end of the experiment, enzyme activity in the blood serum was measured. The increase in the AST level in the first group is associated with changes in hepatocytes. The decrease in ALT activity in the experimental groups is associated with the peculiarities of aluminum excretion. By analogy with AST, an increase in the concentration of LDH was registered in the first group, while a decrease in the level of the indicator was shown in the second and third groups. A decrease in the activity of alkaline phosphatase indicates a violation of metabolic processes in cells. The effect of Al(OH)3 for a month caused certain changes in liver markers in the blood serum of experimental animals. For a more complete understanding of the hepatotoxic effects of aluminum, additional biochemical studies are needed to assess the activity of antioxidant defense enzymes.
ABA-METABOLIZING BACTERIA INFLUENCE THE CONTENT OF ABA, IAA AND CYTOKININS AND REDUCE THE NEGATIVE EFFECT OF THICKENED PLANTING ON GROWTH IN LETTUCE PLANTS
Authors:   Ufa Institute of Biology of the Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia, Martynenko E.V. , Ryabova А.S. ,   Ufa Institute of Biology of the Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia, Kudoyarova G.R. ,   Ufa Institute of Biology of the Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia, Chetverikov S.P. ,   Ufa Institute of Biology of the Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia, Vysotskaya L.B. ,   Ufa Institute of Biology of the Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Russia
Published: November 2024

With increasing planting density, ABA accumulates in plants and their growth is inhibited even before resource deficit occurs. In this study, an attempt was made to mitigate this negative manifestation of competition by inoculating lettuce plants with ABA degrading bacteria belonging to Pseudomonas. In laboratory experiments simulating planting density by the number of plants in a pot (one and three plants), similar abilities of bacteria, P. plecoglossicida 2.4-D and P. veronii IB K11-1 to level out the decrease in plant weight in dense planting were found. Both strains reduced the content of the ABA hormone accumulating in competing plants in the soil and in the shoot, increased the IAA content in the roots and in the soil, which sharply dropped in plants with dense planting, and reduced the zeatin content in the roots. The main mechanism of the positive effect of ABA-degrading bacteria on the growth of lettuce plants is discussed as an increase in hydraulic conductivity and improvement of gas exchange as a result of a decrease in ABA in plant shoots, which was supplemented by the direct effect of bacteria on the content of auxins that activate root growth.
Eldritch Institutions: The Birth of American Asylums, the Founding of Butler Hospital, and a Confrontation with Lovecraft.
Authors: Walker Taylor
Published: November 2024

Insanity and mental maladies have become common tropes within Lovecraftian fiction. Even more omnipresent in these works are cursed locations such as hexed boarding houses and carceral psychiatric asylums where protagonists often end their stories. Yet, the portrayal of asylums in this genre stem from the radically changing and opaque nature of psychiatric institutions and theories that Lovecraft witnessed throughout his life as well as his parents’ own hospitalization within Butler Hospital. This paper will focus on the radically evolving psychiatric theories of the 19th and early 20th century while using Lovecraft’s familial experiences with Butler Hospital as a centering point. A brief history of the field of psychiatry, including supernatural theories as well as the carceral nature of early asylums, will be given up to the founding of Butler Hospital in 1844. Butler Hospital will be used as an example of an initially progressive psychiatric hospital that eventually adopted the standards of care common in the early 1900s American mental healthcare system. Special focus will be placed on the supposedly therapeutic structural design of psychiatric hospitals at the time utilizing the ideas of Luther Bell and Isacc Ray, Butler Hospital’s first superintendent, as an example. Standard practices and procedures at the time of Winfield Scott Lovecraft’s and Sarah Susan Lovecraft’s hospitalizations will be showcased. Speculations on the effects of their treatment and death will be presented as they relate to Lovecraft’s fear of doctors and his writings. Topics that will be addressed include comparative models of 19th and 20th century psychopathology, the founding and transformation of Butler Hospital in the 19th to early 20th century, and the effects on Lovecraft’s life and writings as a result of his parents’ hospitalizations and deaths at Butler Hospital.
THERAPEUTIC INTERVENTIONS FOR MITOCHONDRIAL DYSFUNCTIONS CAUSED BY ALPHA-SYNUCLEIN AGGREGATION IN PARKINSON’S DISEASE
Authors: Vasquez Nathaniel , Rodriguez Jose , Patel Tej
Published: November 2024

Parkinson's disease (PD) is a neurodegenerative disorder denoted by the progressive loss of dopaminergic neurons in the substantia nigra, a brain structure found within the midbrain atop the brainstem. Characterized by tremors and muscular rigidity, the central pathological hallmark of PD is the gradual buildup of Lewy bodies (amyloidogenic fibrils) from the aggregation of α-synuclein, a presynaptic neuronal protein ubiquitous within midbrain neurons. Research has demonstrated that this aggregation disrupts mitochondrial function and homeostasis, causing cytotoxicity and producing excessive reactive oxygen species (ROS), which all lead to neuronal death through mitochondrial stress. Mitochondria homeostasis is crucial to cell life due to its nature of energy production and cell regulation. Through oxidative phosphorylation, mitochondria produce their predominant energy source, adenosine triphosphate (ATP). Neurons then use ATP as a neuromodulator, satisfying the high energy demands of action potentials from dopaminergic neurons. Recent research has proposed irisin, a common myokine (a polypeptide released from myosin during muscle contractions), as a therapeutic intervention to support this homeostatic state. Irisin has been shown to promote mitochondria biogenesis, mitigating the aforementioned dyshomeostatic mechanisms and thus acting as a neuroprotective agent against α-synuclein aggregation and PD. Irisin was able to do this by regulating dynamin-related protein 1 (Drp1) expression within neuron mitochondria, allowing a Goldilocks zone of mitochondria fission and fusion. This perfect balance between over- and under-expression guides this paper through the current medical literature on treatments focused on Drp1 expression in the mitochondria. By discussing the microbiology of PD, illustrating a comprehensive understanding of irisin, and delving into other treatments that may propose similar outcomes, this document will holistically introduce the possible future of PD treatments.
Data Duplication and Errors in Large Medical Datasets: A Case Study in the IRIS® Registry
Authors: Goldberg Eric , Douglas Vivian Paraskevi , Ivanov Alexander , Ross Connor , Elze Tobias , Miller Joan , Lorch Alice
Published: November 2024

Purpose:To investigate entry errors and data duplication within the IRIS® Registry utilizing cataract surgery (CS), YAG capsulotomy (YAG), macular degeneration (AMD), and diabetic retinopathy (DR) records. Design:Retrospective cohort study.Participants:Patients in the American Academy of Ophthalmology IRIS Registry (Intelligent Research in Sight).Methods:We collected records of CS and YAG with specified laterality within the IRIS Registry (years 2013 – 2023), identifying eyes having > 1 record and eyes having ≥ 1 record on a date after the first entry (different date duplication, Dd). Additionally, we collected records of DR and AMD and identified any eyes with either (1) eyes diagnosed with the more severe stage then reverting to the less severe stage or (2) eyes transitioning to the more severe stage before later being diagnosed with the less severe stage, defined as transition errors. We built classification models and evaluated permutation feature importance (PFI) to investigate any relationship between patient demographics, Dd, and transition errors. Main Outcome Measures:For CS and YAG, we measure the proportion of eyes having > 1 procedure record, having > 1 record only on the initial procedure date, and having ≥ 1 procedure record on a date after the first entry. For DR and AMD, we measure the proportion of eyes reverting to an earlier stage after starting at a later stage and the proportion reverting to an earlier stage after transitioning to a later stage.Results:Of 14,718,896 CS-treated eyes, 30.9% had duplicates, with 5.5% having Dd. For YAG, out of 5,113,679 eyes, 29.1% had duplicates, with 4.1% having Dd. For AMD and DR, 7.7% of eyes exhibited transition errors. Models captured a weak relationship between patient geolocation and the data errors under study, indicated by loss of 0.04 (Dd model), 0.014 (transition error model) to F1 score on average by PFI. Conclusions:Data duplication in large medical data sets can obscure the true instances of procedures and diagnoses. We did not find conclusive evidence of a relationship between demographic factors and transition errors or Dd, though model results indicate a weak relationship with patient geolocation.
The Lived Experience of Time in Autism. A Phenomenological Meta-Synthesis
Authors: Wodziński Maciej , Moskalewicz Marcin
Published: November 2024

Purpose. Research on temporal experience in autism spectrum condition is dominated by psychophysical studies that aim to show differences in time processing or perception with neurotypical controls. On the other hand, phenomenological inquiry aims to reach the level of lived experience, but it is substantially lacking regarding this subject.Methods. A meta-synthesis of temporality-related research on autism (210 research articles) grouped into three main domains concerning studies on time processing abilities in autistic individuals, observational and diagnostic criteria, and phenomenological empirical research findings.Results. The research was synthetically organized into three phenomenologically informed categories, allowing a description of the lived experience in autism in terms of disrupted temporality. The three categories are desynchronization (with the world and oneself), certainty and predictability (a sense of uncertainty linked to the unpredictability of world events), and chrononormativity (social demands regarding normative temporal expectations).Conclusion. The major challenge in research on the lived experience of time in autism is the absence of a shared vocabulary allowing for integrating data from different domains. This meta-synthesis proposes phenomenological categories for such vocabulary and informs integrative research across qualitative and quantitative methodologies.
Modifizierte quantitative MRT-Analysemethode zur Identifizierung der Verschiebungsrichtung der lumbalen Bandscheibenhydratation im axialen MRT als Reaktion auf Seitneigung
Authors: Beckford Will
Published: November 2024

Zwischenwirbelscheiben können eine häufige Ursache für Rückenschmerzen sein [1]. Viele Studien haben die Belastungsrichtung des Bandscheibengewebes bei Veränderungen der lumbalen Körperhaltung untersucht [2-9], die in vivo durch die Hydrationsverteilung mittels Magnetresonanztomographie (MRT) analysiert werden kann [10-20]. Das Verständnis der Belastungsrichtung in der axialen Ebene liefert insbesondere mehr Informationen als in der sagittalen oder koronaren Ebene und hilft, Bewegungsmechanismen bei Bandscheibenbedingten Schmerzen zu berücksichtigen.
Time-lapse geophysical responses of hydrogen-saturated rock: Implications on subsurface monitoring
Authors: Li Chao , Bhattacharya Shuvajit , Alhotan Muhammad M. , Delshad Mojdeh
Published: November 2024

Rock physics modeling and time-lapse geophysical modeling are effective methods to better understand the influence of hydrogen on rock properties and visualize hydrogen plume distribution and its migration direction. We study rock physics responses of hydrogen in a wedge model and a small field test scenario under different injection conditions. In doing so, we develop and test an integrated workflow that uses geologic data and dynamic flow simulation of H2 plume migration to simulate corresponding time-lapse geophysical responses, namely, surface (prestack and poststack), cross-hole seismic, and electrical resistivity tomography (ERT) responses. Results from this study will help design effective time-lapse monitoring surveys, in terms of parameter including optimal rate/amount of H2 injection, survey geometry, sensor locations. We investigate the influence of signal-to-noise ratio (SNR), injection location, lithology, permeability, and residual gas saturation on hydrogen monitoring. The choice of rock physics models has a profound impact on the resultant simulations that one can use to effectively design the monitoring surveys.
Utilizing octave_tar and octave_zstd for Efficient Management of Academic Datasets: A New Frontier in Data Science
Authors: Yu Hongbo
Published: November 2024

In the rapidly evolving landscape of data science, the management of large-scale datasets has become a critical aspect of research in fields such as machine learning, deep learning, artificial intelligence (AI), computer vision, and natural language processing (NLP). With the exponential growth of data, the need for efficient tools to handle these datasets becomes increasingly apparent. This paper introduces two powerful yet underutilized tools, octave_tar and octave_zstd, which are developed by CNOCTAVE and Yu Hongbo and designed to facilitate the packing and unpacking of academic datasets within the GNU Octave environment. These tools not only offer a precise and scientific approach to dataset management but also align with the principles of foresight, openness, and innovation in the realm of big data.
Social media use and transdiagnostic dimensions of psychopathology: Relative effects of frequency and problematic social media use
Authors: Lorenzo-Luaces Lorenzo , Boinpally Meghana , Bollen Johan
Published: November 2024

Background: Young adults in the United States are heavy users of social media which has been identified as a possible risk factor for depression. However, it is unclear whether social media use is associated with internalizing disorder symptom vulnerability beyond depression or whether it is related to other relevant symptom dimensions like externalizing symptoms (e.g., substance use). Moreover, it is unclear what aspects of social media use beyond frequency are associated to symptoms. Methods: A large cohort of undergraduate students from a Midwest university (N= 7123) participated in a screening of transdiagnostic symptoms of psychopathology. Data collected included: time spent on social media, social media platforms used, and aspects of problematic social media use (i.e., use for emotion regulation, compulsive use, or social-media-related impairment). We also collected sociodemographics and self-reported symptoms: depression, panic, generalized anxiety, social anxiety, alcohol use, drug use, insomnia, and pain. We correlated depression scores to time spent on social media to confirm prior findings of an association between social media use and depression. We then used a principal components analysis to identify shared dimensions of psychopathology across these symptoms and explored the correlations between symptom dimensions and elements of social media use. Results: Participants who reported higher social media usage exhibited significantly higher self-reported depression. Our PCA suggested two dimensions of psychopathology consistent with the HiTOP model which we dubbed “emotional” and “externalizing” symptoms. Time spent on social media was correlated with emotional symptoms and with externalizing symptoms, albeit to a lesser extent. However, these associations were not significant after controlling for problematic social media use. Moreover, problematic social media use had differential relations to dimensions of psychopathology. For example, using social media for emotion regulation was associated with more severe internalizing symptoms but less severe externalizing symptoms. E-value analysis suggested that unmeasured confounds could potentially explain these associations. Discussion: Our results suggest that the association between time spent on social media and psychopathology could be accounted for by the way in which social media is used, which in turn is differentially associated to emotional and externalizing symptoms. However, unmeasured confounding remains a threat to these inferences.
Construction and Validation of Conduct Disorder Scale: A Clinician and Self-Report Measure
Authors: KOTNALA VARNICA , Singh Anand Pratap
Published: November 2024

Background:The Conduct Disorder Clinician and self-report Scale (CDS-CSR) is a newly developed scale measuring the severity of deviation in behavior. Currently, there are no studies in the establishment of reliability and validity, and factor of measures of conduct disorder among adolescents in India.Objective/Aim: The present study aimed to develop the CDS-CSR and validate the reliability and validity of the scale on the given sample.Method: A Scale of 50 items in the self-report and 12 items in the clinician report scale was developed wherein the items of the scale were decided based on the symptoms & behavioral problems covered under diagnostic guidelines of CD. Subsequently, purposive sampling of 250 juvenile offenders, 84% boys and 16% girls (10–18 years old), with a range of conduct associated with the problem, were administered by a Clinical Psychologist. Result:The internal consistency and inter-rater reliability was found to be significant for clinician and self report subscale of CDS- CSR. In addition, the content correctness index and the face validity of 0.83 & 0.87 was established respectively. The findings suggest that the measures are useful instruments for assessing sexual behavior, disruptive behavior, the environment's effect, and personality problems in children and adolescents. Conclusion:With positive and reversed scoring, the CDS-CSR is a 5-point Likert scale that includes 50 self-report items and 12 clinician report items in a diagnostic index. The Scale is utilized for diagnostic purposes.Keywords: Conduct Disorder, Clinician’s rating, Delinquents, Diagnosis
Does body-specificity stand on solid ground? Z-curving the body-specific association between valence and lateral space
Authors: Dapica Pablo , Solana Pablo , Santiago Julio
Published: November 2024

The body-specificity hypothesis proposes that people with different bodies should also have different conceptual systems. The test case of this hypothesis has been the association of emotional valence (good vs. bad) with lateral space (left vs. right) in people of different handedness. As expected, right-handers tend to associate the good with right space, whereas left-handers show the opposite association. This body-specific effect has been very influential and followed up by an important number of studies. Here, we undertake a systematic examination of the quality of this literature by means of z-curve analysis. The results show that statistical power reaches the conventionally accepted level of 80% in the overall analysis and also in the subset of studies using binomial tasks, whereas it is less concinvingly high in reaction time studies. Moreover, the file drawer rate is low. All in all, the literature about space-valence body-specificity appears reasonably solid, with room for improvement in reaction time tasks.
The rhythmic priming effect in second language perception appears reliant on individuals’ musical background
Authors: Camici Julie , Fiveash Anna , Abdoun Oussama , Kösem Anne , Tillmann Barbara
Published: November 2024

Exposure to musical rhythms has been shown to influence the perception of subsequently presented speech. Until now, this effect has only been studied in native language (L1) processing. The present study investigated whether rhythmic priming could also benefit second language (L2) processing. A musical rhythmic priming experiment was designed based on previous studies in L1 children. Over two experiments, 66 L2 adult speakers of French were asked to detect grammatical errors in naturally spoken French sentences. Sentences were either preceded by a regular or an irregular musical rhythmic prime. We also assessed participants’ French language level, rhythmic perception abilities, and musical training. In Experiment 1, participants from various L1 backgrounds were recruited. In Experiment 2, only participants with a Latin native language were recruited. For both experiments, grammaticality judgments did not differ after regular versus irregular rhythmic primes. However, grammaticality judgments correlated significantly with rhythmic abilities, suggesting that participants with better rhythm perception were better at grammaticality judgment tasks. Moreover, musicians were better at detecting grammatical errors than those who had not received music training. We also found that the rhythmic priming effect (better grammatical judgments after regular than after irregular rhythms) increased with the number of years of musical training, suggesting that regular rhythmic primes may improve L2 perception in particular for musically trained participants. The results offer promising perspectives on the use of musical rhythmic primes as a means of improving language skills in second language acquisition, and on the potential impact of musical training on language processing.
Embracing Open Science in Qualitative Organizational Research: Extant Areas of Integration and Future Possibilities
Authors: Endacott Camille , Reed Brent , Steltenpohl Crystal Nicole
Published: November 2024

Despite growing support for and interest in open science in leadership research, many popularly recommended practices have been primarily designed for post-positivist, quantitative research. We argue that qualitative researchers have largely been overlooked in guidance on participating in open science, but that the shared values among interpretivist qualitative research and open science offer many opportunities for converging practices. Central values of open science, including openness, integrity, and rigor, have long been espoused by qualitative researchers and enacted in practice. However, we argue that there is even more potential for qualitative researchers to participate in open science by enacting practices that have been appropriately designed or modified for qualitative methodologies. We present seven open science practices that we suggest that qualitative researchers adopt to further the openness, integrity, and rigor of our scholarship. We close by discussing the implications of these practices for researchers across methodologies and communities of practice.