bluuebunny/crossref_metadata_2025 huggingface dataset:
A Scientific Analysis of Rusty Textiles from the Gaya Period Excavated at No.63 Tomb Gyodong, Changnyeong
Authors: An Boyeon , Pak Seonghee , Lee Ryangmi
Published: January 2023

This study presents the results of an analysis of the rusty textile around the gilt-bronze crown and silver belt discovered during an excavation survey of Tomb No. 63 in Gyodong, Changnyeong, South Korea, in 2020. Microscopic observation was conducted to observe the conservation and weaving states of the textile, and cross/side-sectional investigation was performed for fiber identification. Scanning electron microscopy (SEM) and Fourier-transform infrared spectroscopy were also carried out. The number of layers of the fabric in the gilt-bronze crown could not be determined because of severe fiber degradation. However, the silk fibers in the triangular cross-section of the fabric were confirmed to have twill and plain weave patterns. The fabric around the silver belt featured a round cross-section. SEM and cross/side-sectional investigation revealed that this fabric consisted of wool fibers. Gyodong Tomb No. 63 is an important relic of the Gaya period, which was verified atas a historical sites of the late 5th century, and were identified diagonally patterned fabrics, such as silk twill. This study is significant because we obtained data on ancient wool fibers by performing an extensive examination of the wool tabby that had only been previously described in the literature.
An Application and Technology of SWIR Hyperspectral Image for Inconspicuous Textile Pattern Analysis
Authors: An Boyeon , Yoo Ji Hyun , Ahn Yu-bin
Published: January 2023

This study applied short-wave infrared (SWIR) hyperspectral imaging technology to analyze the textile pattern used in the Jeogori of Baekdamsa Temple. First introduced in 1748, the Jeogori is a very important relic in the study of Korean traditional costume. The garment w as designated as a national treasure in 1993, and the pattern in its yellow silk has been well established. However, obtaining the pattern information of its reddish purple decoration has proven to be quite challenging. In contrast to yellow, reddish purple is a color that is difficult for a camera to recognize; thus, analyzing patterns in this color using only high-definition digital or infrared photography is difficult. In this work, SWIR hyperspectral imaging technology, which has recently been used in investigations of cultural heritage sites, was applied to identify the textile pattern on the Jeogori of Baekdamsa Temple. The technology successfully identified the patterns of a Wan-character, dragon, and phoenix. This type of textile pattern was identified in Korea from the end of the 17th century to the early-to-mid-18th century. This study is meaningful because it not only provides a detailed image of the textile pattern on the Jeogori of Baekdamsa Temple, which has not been previously achieved, but also proposes a new strategy based on hyperspectral imaging technology for studying the cultural heritage of textiles.
Red List of lichenized fungi in Bulgaria
Authors:   Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, Shivarov Veselin V. , Denchev Cvetomir M. ,   Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, Denchev Teodor T. ,   Institute of Biodiversity and Ecosystem Research, Bulgarian Academy of Sciences, 2 Gagarin St., 1113 Sofia, Bulgaria
Published: January 2023

The first Red List assessment of lichenized fungi reported from Bulgaria is presented. The IUCN Red List criteria were applied to 138 species to assess their current extinction risk and to highlight the main threats for them. Our results revealed that six species are Regionally Extinct (RE), 23 species are Critically Endangered (CR), 20 species are Endangered (EN), 13 species are Vulnerable (VU), 11 species are Near Threatened (NT), 58 species are Least Concern (LC), and seven species are Data Deficient (DD). The most important floristic regions for lichen conservation are the Pirin Mts (26 species), the Balkan Range (25), the Rila Mts (25), the Rhodopes (20), Mt. Vitosha (16), Mt. Strandzha (16), and the Black Sea coast (15). The main threats are development of tourism and recreation activities that destroy habitats (60 species affected), air pollution (55), climate change (53), development of tourism and recreation areas (41), harvesting trees and other woody vegetation (unintentional effects) (27), ecosystem modifications that convert or degrade habitats (18), and development of housing and urban areas (14). The information provided in this Red List will assist to further develop the national conservation strategy for Bulgaria.
The Two 'Greek Buddhas'
Authors: Dimou Nikos
Published: January 2023

This article discusses the influence of Indian Buddhism on Greek Skepticism and their philosophical method of stress management through the Greek philosopher Pyrrho of Elis. That influence was the subject of two books with similar titles mentioning the “Greek Buddha,” as Pyrrho was called by Nietzsche. Both books, one written in Greek from a layman’s perspective approximately 40 years ago and one written in English from a scholarly perspective approximately 6 years ago, discussed the similarities of the Eastern and Western traditions in terms of the goal of serenity, ataraxia. The book published in 1984 was the first one in Greece to link Greek Hellenistic Philosophy to Oriental Wisdom and especially to the early Philosophy of Buddhism. Both traditions offer a practical way of philosophical management of everyday stress and suffering through the mentality of suspension of judgement and non-attachment to certainties.
Living Happily in the Era of COVID-19: Philosophical and Positive Psychology Intervention in Secondary Education
Authors: Michopoulou Eleni
Published: January 2023

In the coronavirus pandemic crisis, the mental well-being of adolescents was significantly burdened and, in this context, an innovative school intervention program was applied and its effect was investigated. The program involved a structured 11-weeks-long psycho-educational intervention on a sample of 11 Greek high school students (aged 16-17 years), combining principles of Epicurean and Stoic Philosophy with Positive Psychology techniques, aiming at promoting their mental well-being and the effective management of the psychological effects of the pandemic crisis. A qualitative methodology was used for data collection, including triangulation and data enrichment, self-referential demographic questionnaires, focus group and group interviews, semi-structured individual oral interviews and written descriptions and narratives. Before the intervention, the students’ needs and expectations were investigated through written narratives and, after the intervention, semi-structured individual oral interviews and group interviews recorded their personal experiences and evaluative judgments. The application of positive techniques of meaning in life, optimism, gratitude and the development of positive relationships, combined with a cognitive reconstruction based on the principles of Epicureanism and Stoicism, had beneficial effects on the participating students, including emotional state improvement, mental well-being enhancement, and improved aspects of quality of life, such as subjective health, cognitive and school performance, family and interpersonal relationships. The highlight of the study was the emergence of the supporting role of Philosophy in the effectiveness of the applied techniques of Positive Psychology in the management of the psychological and social impact of the COVID-19 pandemic.
Epicurean Stability (eustatheia): A Philosophical Approach of Stress Management
Authors: Yapijakis Christos , Chrousos George P.
Published: January 2023

Epicurus used an empirical and sensualistic approach to knowledge, creating a consistent, naturalistic, pragmatic and consequentialistic philosophy. The scientific observations of the last centuries have confirmed the basic principles of Epicurean physics, as well the psychotherapeutic approach of Epicurean ethics, which fits human nature. We know from the work “On Frank Criticism” of Epicurean philosopher Philodemus of Gadara, that the teaching methodology of Epicureans included psychoeducational counseling through therapeutic criticism based on friendly freedom of speech and aiming at τῆς ψυχῆς θεραπείαν (psychotherapy) and at knowledge of maintaining mental health and well-being. The Epicureans called εὐστάθεια (eustatheia, “stability”) the psychosomatic balance (τὸ τῆς σαρκὸς καὶ ψυχῆς εὐσταθὲς κατάστημα), which today we call homeostasis (ὁμοιόστασις), and considered it the basis of true happiness. They recognized empirically the stress that disturbed psychosomatic homeostasis as an agitation of the psyche or a painful feeling of the body and used a number of mental and affective techniques (including the tetrapharmakos) to manage stress at its onset, so that it does not evolve into the particularly troublesome conditions of anxiety and/or depression, which may become chronic psychosomatic disorders with significant social consequences. The article discusses the relation of the main ethical teachings of Epicurus with the biological basis of human brain functions and with the management of stress by cognitive and behavioral psychotherapy.
Current trends in the development of pedagogical systems of ukraine in the conditions of digitalization of society
Authors: Potapchuk Olha
Published: January 2023

The purpose of the work is to analyse the current trends in the development of domestic pedagogical systems in the context of digitalization of society.

The research methodology consists in the use of methods of scientific analysis, pedagogical positions on the issues of digitalization of education, implementation of systemic and integrative approaches.

The scientific novelty consists in highlighting the main trends of the prospective pedagogical system. The main trends include: humanization and humanitarianization; national orientation; openness; science; continuity; digitalization. An analysis of each trend is presented and their role in the development of education is determined. It has been established that the digitalization of education creates prerequisites for the wide implementation of psychological and pedagogical developments in pedagogical practice, which allow to intensify the educational process, implement learning ideas, including within the framework of new models.

Conclusions. Summarizing the analysis of the main trends and features of pedagogical systems at the current stage, it is very important to take into account the orientation of global educational processes. This is primarily an orientation to the individual, development of creative potential; openness of education as a condition of professional flexibility, mobility of a specialist, his ability to self-education and professional self-development; the need for interconnection and coordination of various stages of professional training, retraining and advanced training. Therefore, in order to modernize the pedagogical system of Ukraine, the national traditions and prospects of the country should be determined, taking into account the current trends in the development of digital technologies and the experience of foreign education systems.
SPIS ŚLUBNEJ WYPRAWY HELENY KATARZYNY DZIAŁYŃSKIEJ, ŻONY ZYGMUNTA WIKTORA DENHOFFA Z DNIA 27 PAŹDZIERNIKA 1681 ROKU
Authors: Dziembowski Piotr Maciej
Published: January 2023

W Archiwum Państwowym w Poznaniu znajduje się zbiór dokumentów dotyczących majątku Konarzewo. W aktach tych, w serii Akta rodzinne rodów, do których Konarzewo przejściowo należało oraz akta ich posiadłości leżących poza Konarzewem, znajduje się dokument powstały w związku z małżeństwem Heleny Katarzyny Działyńskiej z Zygmuntem Wiktorem Denhoffem. Dokument ten datowany na 27 października 1681 roku jest spisem rzeczy, które Helena otrzymała jako swoją wyprawę od ojca Zygmunta Działyńskiego, wojewody kaliskiego. Ze spisu dowiadujemy się o przekazanych kosztownościach, ubiorach i rzeczach codziennego użytku. Wykaz tych wszystkich rzeczy świadczy o dużej zamożności ojca Heleny – Zygmunta Działyńskiego.
POJĘCIE „DYSTANSU” W RELACJI PACJENT – PERSONEL MEDYCZNY I JEGO WYMIAR PERSONALISTYCZNY
Authors: Gliniecki Wojciech
Published: January 2023

Pobyt osoby chorej w szpitalu jest często momentem jej buntu i niezrozumienia sytuacji. Personel medyczny ma rolę fundamentalną nie tylko leczyć, ale i wejść w dialog z pacjentem, towarzyszyć w akceptacji danej sytuacji. W niniejszej pracy autor wprowadza pojęcie właściwego dystansu jako przestrzeni dialogu między personelem medycznym a pacjentem. Artykuł akcentuje szczególnie charakter personalistyczny dialogu. Tak ujęta relacja chroni człowieka jako osobę, jego człowieczeństwo i godność. Nasze refleksje ukazują konieczność dystansu personelu medycznego z osobą chorą po to, aby relacja między nimi była właściwa i ukierunkowana na dobro osobiste człowieka. Dystans nie jest zatem brakiem uczuć. Jest to przestrzeń właściwego dialogu, opartego na szacunku do osoby chorej, jak i do personelu.
IKONOGRAFICZNA KONCEPCJA PRZESTRZENI CHRZCIELNEJ W SZTUCE WCZESNOCHRZEŚCIJAŃSKIEJ. STUDIUM W PERSPEKTYWIE DOMUS ECCLESIAE W DURA-EUROPOS, SYRIA
Authors: Szajda Mariusz
Published: January 2023

Odkryty w 1920 roku na terenie Syrii, w Dura-Europos, wczesnochrześcijański kościół jest obecnie najstarszym odnalezionym miejscem spotkań wspólnoty wyznawców Chrystusa. Poddając badaniom odkrycia archeologiczne prowadzone w tym miejscu, w znacznym stopniu przez naukowców z Yale Uniweristy, odnaleźć można bogactwo kulturowe chrześcijan w pierwszej połowie III wieku. Analiza częściowo zachowanych fresków, wypełniających przestrzeń baptysterium w Dura-Europos, staje się świadectwem wiary i elementem charakterystyki nie tylko sztuki wczesnochrześcijańskiej, ale nadto bogactwa duchowości pierwszych wyznawców Chrystusa. Wyraźnie wyodrębnione w domus ecclesiae pomieszczenia przeznaczone na spotkania wspólnoty, nauczania katechumenów oraz baptysterium, wskazują na istotny w tym okresie proces kształtowania się sfery kultycznej i katechetycznej. Analiza ikonografii odkrytej w baptysterium, umożliwia poznanie fundamentu teologicznego i filozoficznego, jaki znajdował się u podstaw rozumienia sakramentu chrztu w najwcześniejszym okresie formowania się liturgii Kościoła wczesnochrześcijańskiego.
Sobre la compatibilidad del incremento del 20% en la pensión de incapacidad permanente total con el percibo de una pensión extranjera.
Authors: Díaz Mordillo Maria Alexandra
Published: January 2023

La falta de regulación específica en materia de incapacidad permanente total cualificada ha ocasionado que el complemento se articule en torno a la doctrina judicial tanto de tribunales españoles como de la Unión Europea. Uno de los principales puntos de fricción es el de la compatibilidad con otras rentas del interesado, dificultad que crece cuando se trata de pensiones causadas al amparo de los instrumentos internacionales de coordinación de sistemas de Seguridad Social de los que España participa. La STJUE de 15 de marzo de 2018 (asunto C-431/16) ha unificado criterio en cuanto a las pensiones causadas en el ámbito de la Unión Europea, Espacio Económico Europeo y Suiza, pero su aplicación no es exportable a Convenios Bilaterales o al Convenio Multilateral Iberoamericano de Seguridad Social. A pesar de la importancia del cambio producido, no se ha incorporado todavía el ansiado cambio normativo que clarifique las innumerables situaciones objeto de litigio.
History and scope of social human rights for irregular migrants.
Authors: Mendizábal Bermúdez Gabriela
Published: January 2023

Una de las principales interrogantes respecto a los derechos humanos de las personas migrantes en situación migratoria irregular es si tienen o no derecho a las prestaciones de los derechos sociales, los cuales además son parte de los derechos humanos. Este artículo muestra cómo las leyes internacionales que reconocen los derechos humanos, a medida que evolucionaron, han logrado evitar la exclusión basada en el estatus migratorio. Sin embargo, las reglamentaciones administrativas nacionales no siempre están en consonancia con las leyes internacionales. Para llegar a esta conclusión, el estudio parte del análisis de la evolución histórica de los derechos humanos vigentes en el continente americano, las convenciones y recomendaciones de la OIT sobre el derecho al trabajo y la seguridad social de los trabajadores migrantes, los instrumentos internacionales de la ONU regionales, y finalmente, el estudio de la protección de los derechos humanos sociales de los migrantes irregulares en México.
Bridging the gap of follow-up care for high-risk patients with established coronary artery disease
Authors: Bowers Nicola
Published: January 2023

In this month’s BANCC column, Nicola Bowers emphasises the importance of secondary prevention in acute coronary syndrome. Nicola is president elect of the BANCC and clinical academic nurse lead for integrated medicine at Buckinghamshire Healthcare NHS Trust.
Motor neurone disease
Authors: Winter George
Published: January 2023

George Winter looks at the current resources being dedicated to motor neurone disease, the funding problems new research is currently encountering, and the moral obligation we have to continue improving the quality-of-life for those with the disease
Non-medical prescribing in primary care in the UK: an overview of the current literature
Authors: Armstrong Amanda
Published: January 2023

Background

Non-medical prescribers are perceived as a complement to busy general practice in primary care.

Aim

To conduct an overview of the literature available on the role and impact of non-medical prescribers on primary care patients.

Method

A search was conducted using multiple databases to find articles published between January 2015-January 2021. Inclusion criteria: non-medical prescribers in primary care in the UK, written in the English language. Exclusion criteria: research conducted in secondary care or outside the UK.

Findings

285 studies were identified; 15 were eligible for critical appraisal. The key themes were: non-medical prescriber's positive perceptions were autonomy, job satisfaction and colleague support. The negative perceptions included risk, lack of continuous professional development and organisational support.

Conclusion

By reviewing the perceptions of non-medical prescribing in primary care, organisations can ensure when employing new non-medical prescribers that adequate continued professional development and support is in place. Thereby reducing the concerns of non-medical prescribers about the ligation risk of prescribing.
Multinomial Logistic Regression for The Analysis of Career Decision Style in Teacher Education
Authors: Widiyanto Widiyanto , Nurkhin Ahmad , Yulianto Arief , Daud Norzaidi Mohd
Published: January 2023

This study aims to identify students' styles of career choices. The second aim is to investigate what factors influence career choice style. The third aim is to determine whether all students of education programs want to become teachers one day. This research model is a relational model that uses multinomial logistic regression. The research population was Universitas Negeri Semarang (UNNES) students of education programs from five faculties in 2018. The number of people in the population was 4,531, and the participants were 220 students. The data analysis consisted of the multinomial logistic regression method. The results showed that the model met the requirements for use. Factors affecting career decisions are gathering information, locus of control, decision-making speed, and aspiration of an ideal career. Career choice has five styles: rational, intuitive, spontaneous, dependent, and avoidant. Accordingly, the spontaneous style is most commonly used by students. The other result shows that the factor that most influences students in choosing a style is pursuing an ideal career.
Examining the Associations Between Calibration Accuracy and Executive Functions in Physical Education
Authors: Samara Evdoxia , Kolovelonis Athanasios , Goudas Marios
Published: January 2023

This study examined students’ calibration of performance in a sport skill in relation to their performance in an executive functions test. A total of 265 students in the fourth, fifth, and sixth grades participated in the study. The students took an executive functions test, and then they were tested on a basketball shooting test, after having provided a personal estimation regarding their performance. Based on students’ actual and estimated performance, the bias index was calculated to classify students into three categories; accurates, underestimators and overestimators, while the accuracy index (absolute values of the bias index) was also calculated. The results showed a positive but small magnitude relation between students’ scores in the executive functions test and their performance calibration, while accurate scored higher on the executive function test compared to over estimators and under estimators. These results are similar to those of previous studies with elementary school children that employed cognitive tasks and were discussed with reference to theoretical and empirical implications.
The Legs of a Tripod: Correct Radiography, Correct Diagnosis and Correct Treatment
Authors: Gulsahi Kamran
Published: January 2023

The dentist can evaluate and precisely diagnose many oral diseases by radiographs. Correct and detailed clinical and radiographic evaluation is crucial for a successful treatment. The correct diagnosis and therapy depends on the fact that the dentist must properly use every instrument and interpret the results correctly. This case series emphasize 3 cases which presents challenging clinical circumstances for a clinician to diagnose and treatment planning.
Hopelessness..? Turned Hopefullness..! – Salvaging A Molar with A Mother’s Touch– Case Report
Authors: Elangovan Ramnath , Theyagarajan Ramakrishnan , Dhas Mejalla Muthiah Amala , Sekhar Vidya
Published: January 2023

Periodontitis is the inflammatory disease that leads to destruction of the supporting structures of the teeth. The early diagnosis and treatment of periodontitis is always not possible as the periodontitis progress with minimal or no pain. Regenerative medicine is the field that uses exogenous or endogenous stem cells for the regeneration of the lost periodontal tissues. This case report presents about salvaging a molar which was of poor prognosis and at the verge of extraction using Amniotic Membrane as a barrier membrane in the procedure of Guided Tissue Regeneration.
Role of Laminin in Oral Carcinogenesis
Authors: Preeti Ahankare , Gokul Sridharan , Sangeeta Patankar
Published: January 2023

Oral carcinogenesis is characterized by significant alterations occurring at the phenotypic and genotypic level resulting in uncontrolled proliferation and evasion of apoptosis. With growing tumor mass, a switch of metabolism and angiogenesis becomes important for the further development of the disease. Invasion and subsequent metastasis of the malignant cells are basic requirement for tumor promotion and progression. Cell migration plays an important in embryogenesis, inflammatory immune response, wound healing and cancer invasion. One of the important factors responsible for the tumor progression is the alteration seen in extracellular matrix proteins. Extracellular matrix (ECM) includes a group of structural proteins, glycoproteins, and proteoglycans that function as a physical scaffold to maintain tissue structure and provides biochemical signals to modulate cellular function. Basement membranes are thin layers of ECM that form the supporting structure under epithelial and endothelial cells. The protein composition of basement membrane is mainly inclusive of type IV collagen, laminins, entactins, and proteoglycans. Laminin is biologically active part of the basement membrane and influences cell differentiation, migration and cell adhesion. They are an important and biologically active component of the basal lamina, influencing cell differentiation, migration, and adhesion. Laminin reflects the integrity of basement membrane better than the other extracellular matrix (ECM) proteins and thus, may be used as a marker suggestive of the basement membrane status during tumorigenesis. Oral squamous cell carcinoma is an important epithelial malignancy and altered laminin expression in OSCC is an important process in its invasion and metastasis. An understanding of the role of laminin in OSCC may aid in its utility as a biomarker to determine the prognosis and treatment planning of OSCC.
Optimizing Medical Air Production Using Exergy and Process Cost Analysis
Authors: Braimah M. N. , Anozie A. N. , Braimah R. O.
Published: January 2023

This work compared one new design of Air separation using Linde process for medical air production with existing plant using exergy and process cost analyses. Hyprotech System Simulator (HYSYS) software was used in simulating the process plants and Microsoft Excel was used for exergy, energy and process cost analyses. Annual profit was used as fiscal index for comparism with existing plant design. Exergy analysis of Linde air separation process showed that exergy efficiency of the existing plant (base case) was 3.23 kJ/h while that of the improved plant when the valve was replaced with a turbine (Case 1) was 11.65 kJ/h. Also, the process cost analysis showed that the annual profit for the base case was 48,818,463 ($/yr) while that of the improved case was 50,485,051 ($/yr). Replacing the valve with the turbine in the Linde air separation process could greatly give a better air separation process in terms of high purified medical air with greater annual venture profit.
Investigating Electrochemical Behavior of Antibacterial Polyele-ctrolyte-Coated Magnesium Alloys for Biomedical Applications
Authors: Seraz M.S. , Uddin M.N. , Yang S.Y. , Asmatulu R.
Published: January 2023

This study presents corrosion rates of layer-by-layer (LBL) and self-assembled monolayer (SAM) coated magnesium (Mg) alloys, and their antibacterial properties. Mg alloy samples were coated with cationic (chitosan - CHI) and anionic polyelectrolyte (carboxymethyl cellulose-CMC) LBL coating, and phosphonic acid self-assembled monolayer (SAM) coating methods. Electrochemical impedance spectroscopy (EIS) was employed for analyzing these samples in order to detect their corrosion properties. During the electrochemical analysis, a corrosion rate of 72 milli inch per year (mpy) was found for the sample coated with a 12 deionized phosphonic acid SAM and 9 CHI/CMC multilayers. During the antibacterial tests, gentamicin was investigated about how it would adhere on the Mg substrate surface and how it would be an antibacterial agent against Escherichia coli (E. coli) bacteria. From a coating point of view, a bare layer, self-assembly monolayer, polyelectrolyte layer, and combination of LBL and SAM were analyzed. From an antibacterial treatment point of view, samples with no antibacterial treatment, 10% gentamicin sulfate, UV treatment and 0% gentamicin sulfate, anti-anti and 10% gentamicin sulfate, and 70% ethanol and 10% gentamicin sulfate were individually studied. Duration of the incubation was 7 days at 35°C. Antibacterial sensitivity was tested using the disk diffusion method in Petridish. Based on the standard diameter of the zone of inhibition chart, the growth of bacteria was inhibited relatively with those Mg substrates. The largest recorded diameter of the zone of inhibition was 50 mm for the pre-UV treated and gentamicin-loaded sample, which is more than the standard inhibition diameter.
A Holistic Approach to Stormwater Green Infrastructure
Authors: Mirza Sana , Nie Jing , Viteritto Michael , Feng Huan
Published: January 2023

One of the factors that threaten fresh water quality is the input of anthropogenic nutrients, a problem heightened in urban areas with lots of impervious surfaces. The implementation of stormwater green infrastructure allows stormwater runoff to be filtered before entering waterways, reducing nutrient input. Stormwater green infrastructure includes installations such as green roofs, green alleyways, and parks which can provide environmental, mental and physical health benefits to local residents who may have lacked access to green space. However, such installations can also have the counter intuitive effect of gentrification, termed the ‘green space paradox’. Through the review of published literature and case studies, a holistic design of stormwater green infrastructure implementation is presented in this study, which includes public participation, sustainability, and equity of distribution.
Characterization of Water-Soluble Ions in PM2.5 in Chongqing, a Megacity in Eastern Sichuan Basin, China
Authors: Song Tianli , Cao Xuyao , Wang Huanbo , Qiu Yang , Chen Yang , Tian Mi , Yu Jianyan , Zhai Chongzhi , Yang Fumo
Published: January 2023

Samples of PM2.5 were collected at three urban sites and one rural site simultaneously in Chongqing, the only megacity in eastern Sichuan Basin, Southwest China, from October 15 to November 13, 2015. Water-soluble ions (WSIs, i.e., F–, Cl–, NO3–, SO42–, K+, Na+, NH4+, Mg2+ and Ca2+) in PM2.5 were measured to investigate their characteristics and formation pathways. The average concentrations of PM2.5 at the urban sites were 55.5–59.0 µg m–3, which was 62.8–73.0% higher than that at rural site. SO42–, NO3–, NH4+ were the dominant ions, contributing to more than 90% of total WSIs. The coefficients of divergence for SO42– between the urban and rural sites were 0.15–0.17, indicating its relatively uniform distribution across Chongqing. Analysis of the formation mechanisms of SO42– and NO3– in PM2.5 suggested that the heterogeneous reaction was responsible for the high concentrations of sulfate among the four sites, whereas nitrate was formed mainly through homogeneous reactions at the urban sites. Furthermore, the results of trajectory clustering showed that the air pollution were mainly from local sources within the basin. Our findings on PM2.5 composition in Chongqing help to advance the knowledge on PM2.5 pollution in Chinese megacities, and to provide more evidence for further pollution mitigation.
Technical and Economic Feasibility of Generating Renewable Energy from Wastewater Treatment Using Microbial Fuel Cells: The West Bank as Case Study
Authors: Haddad M. , Joudeh O.
Published: January 2023

The technical and economic feasibility of microbial fuel cell use in wastewater treatment for energy and resource recovery was investigated. A double chambered-MFC model (DS-MFC) operated by primary effluent wastewater as substrate was used. Four different COD-MFCs groups were constructed in three duplicates (input COD from 342 to 1733 mg/l). Initial COD value, electrode type, and salt bridge size and its concentration were set and fixed for each MFC group. After 15 days-startup period the MFCs were operated for 30 days. COD was measured for the twelve MFCs every two days and output voltage was measured every 24 hours. Results revealed that the COD of the substrate used in MFC at any time is related proportionally to output voltage from that MFC, and a logarithmic model was found that can be used to predict COD for a wastewater sample by measuring output voltage of MFC operated by that sample. Maximum COD removal percentage achieved in this study was 87.1 % which agrees with published research. A maximum output power achieved was 0.585 W/m3 treated. It was found that COD removal behavior for the first group (typical wastewater composition) was second order while the other three groups with higher concentrations was first order. The payback period of the system under consideration was estimated at 8.3 years (infeasible). If we include the environmental and energy challenge benefits of the system to its economic feasibility, the system feasibility could be considered appropriate.
GIS Analysis of Temperature Variation in Ukraine for 2000-2020
Authors: Shults Roman , Annenkov Andriy , Isaev Oleksandr , Nesterenko Olena
Published: January 2023

The presented paper is dedicated to the problem of temperature changes variations for Ukraine. As an input data source, NOAA National Centers for Environmental Information data were used. Based on preliminary studies, the temperature analysis workflow was developed. The feature of the deployed workflow is an application of GIS analysis for temperature trend detection. As the main functions of GIS analysis, overlay analysis and Kriging interpolation were used. The temperature surfaces were constructed using the Kriging interpolation method to determine the temperature trend. The overlay analysis was applied based on the temperature surfaces for different time intervals. After overlaying procedure, the difference between two georeferenced surfaces was calculated. These differences allowed us to track the temperature changes throughout time. The results of surfaces subtraction were used for temperature variation analysis for different time intervals. The general picture emerging from the research is that the temperature grows for 0.2 C° each five years. As in previous studies, the results confirm that there is a distinct tendency in the temperature rising for one degree of Celsius during the last twenty years. The temperature trend has an essential geographical association. The most significant temperature changes are related to the southeast of Ukraine, proving the desert regions' increasing.
Numerical Analysis of Magnetic Nanoparticles Penetration within the Cancerous Tumor Tissue under Influence of External Magnet
Authors: Ali Ne’mati Sayyed Mohammad , Ghassemi Majid , Shahidian Azadeh
Published: January 2023

Using the great magnetic drug carriers (MDCs) is proposed mechanism to reduce and increase the toxic drugs penetration within the healthy and cancerous tissues, respectively. The purpose of current study is to investigate the penetration of magnetic drug carriers within the cancerous tumor tissue under the influence of external magnet. In order to solve the coupled governing equations an in house finite volume based code is developed and utilized. Capillary wall and tumor tissue is modelled as a saturated porous media. Results show the penetration of MDCs into the tumor in the absence of magnetic field is minimal and is limited to the surface of the tumor. On the other hand, under the influence of external magnet the penetration of MDCs within the tumor increases exponentially.
Interpretation of Platelets in The Horse
Authors: Satué K. , Gardón J. C. , Muñoz A.
Published: January 2023

Currently we can consider that, in addition to its role in hemostasis, platelets also participate in other important processes such as thrombosis, inflammation, tissue remodeling and the innate defense mechanisms. The hemostatic activity of platelets includes different events to stop bleeding. Within these functions we can mention the adhesion to the endothelium of the affected blood vessel, the activation, the aggregation, and the release of substances that initiate hemostatic events, and also the providing a phospholipid surface for activation of numerous coagulation factors. Similarly, platelets release multiple growth factors responsible for regulating the growth and division of endothelial cells and fibroblasts. In this way, among other things, angiogenesis and tissue regeneration are favored. Platelets also participate in inflammatory processes by the release of factors that initiate the inflammatory cascade and favor the chemotaxis of neutrophils, monocytes, macrophages, acute phase proteins and target cell signaling. Finally, platelets participate in the immune response by interacting with the complement system and immunoglobulins.
Outcomes and Barriers to Use of Novel Sickle Cell Therapeutic Agents in a Community Health Center
Authors: Metzger Anne H. , Anim Mamle , Johnson Cherika
Published: January 2023

Sickle cell disease is genetic red blood cell disorder transmitted via an autosomal recessive mutation due to valine replacing glutamicacid on the beta globulin chain of the hemoglobin molecule. The disease impacts millions of people worldwide majority living in sub-Saharan Africa and India and impacts approximately 100,000 Americans mostly those of African descent. [2-3] In 2019, two novel treatment agents for sickle cell anemia, crizanlizumab (Adakveo) and voxelotor (Oxbryta) were approved by the United States Food and Drug Administration (US FDA) [7, 8]. Both medications offer sickle cell patients improved control of their disease by reducing sickling of the red blood cells (voxelotor) and the painful effects of vaso-occlusive crises, (crizanlizumab). We studied the effects of crizanlizumab and voxelotor on a population of patients in a sickle cell clinic. Fifty-two charts were reviewed for inclusion in the study; 12 patients were using crizanlizumab and 12 patients were using voxelotor. Eight patients met criteria for evaluation of crizanlizumab and 7 patients for voxelotor. Of all data collected, the only significant difference between baseline measures and post-therapy measures was for voxelotor and hemoglobin levels at baseline and at 3 or more months post therapy. This was a small study which reflects the experience of one clinic; sickle cell providers must continue to address the social determinants of health, psychosocial and psychological needs of their patients in addition to prescribing these novel medications.
Multidisciplinary Development Issues of Hematopoietic Stem Cell Transplantation Program in Ukraine: Role of Auxiliary Cryopreservation Technologies
Authors: Kalynychenko Tetiana O.
Published: January 2023

Hematopoietic stem cell transplantation (HSCT) is a life-saving medical technology for many serious diseases. Active international exchange of transplant material is ensured through productive cooperation of world international donation, transplantation, cell therapy organizations, along with their associations. Analysis of the experience of many countries has allowed the development of key recommendations from the Worldwide Network for Blood and Marrow Transplantation for establishing HSCT programs. According to them, to make the most effective use of the capabilities of this medical technology, the creation of new transplant programs requires both sufficient investment and the presence of specialized professional teams for multidisciplinary support of the entire process.

This article discusses prospects for the development of the national transplant program in Ukraine. In particular, the role of Ukrainian national scientific and practical traditions detailed in the creation of cellular processing technologies and cryopreservation as part of the team support providing components of transplantation medical technology. It is looked forward that the development of the HCST program in Ukraine will take place through continuous improvement in order to meet the criteria of the highest quality and safety. Its serious basis is the solid scientific traditions, historical and modern experience of many directions that provide the field.
Multicenter Study of Pyruvate Kinase Deficiency in Argentina
Authors: Pepe C. , Eberle S. Eandi , Donato H. , Basack N. , Baña M.F. Tisi , Cedola M.A. , García E. , Rapetti M.C. , Rubulotta E. , Milanesio B. , Bisio A. Maquijo , Cichierichetti M.A. , Lazarowski A. , Gomez V. Avalos
Published: January 2023

The red blood cell (RBC) pyruvate kinase deficiency (PKD) is the most common recessive congenital defect of glycolytic enzymes associated with non-spherocytic hemolytic anemia. It is a rare hereditary disorder caused by >300 variants in the PKLR gene. This is a retrospective study of 19 patients from different centers from Argentina with confirmed molecular diagnosis of PKD. Clinical follow-up was carried out from birth in most cases. Five consanguineous patients from “gypsy” community, were homozygous for the “PK-Gypsy deletion” (PK-Gd). During the neonatal period they developed anemia with icterus. Transfusion exchange was required in 60%, light therapy in 80%, and RBC transfusion in 80%. During the follow-up iron overload was detected in the 100%, cholecystectomy was indicated in 40%, and splenectomy in 60%. Thirteen cases had 2 missense variants (MS), being the Mediterranean variant (p.Arg486Trp) the more frequent detected (26%).Only 1 patient had a missense-splicing mutation combination. During the neonatal period, 86% had anemia and icterus. Light therapy was required in 78%, transfusion exchange in 21% and RBC transfusion in 64%. During the follow-up iron overload was detected in 57% and splenectomy was indicated in 43%. Transfusions (pre-splenectomy and post-splenectomy) were more required in PK-Gd cases as compared with patients with point mutations (100%/60% vs 71%/29% respectively). Our data indicates a high clinical-therapeutic-molecular heterogeneity in PKD patients with the PK-Gd group presenting the most severe cases.
Multidisciplinary or Monotherapy? Effects of Multidisciplinary Approach in Sotos Syndrome
Authors: Bingöl Rahime Hülya , Turna Fatma , Gagachovska Biljana , Kocabasoglu Nese
Published: January 2023

Objectives: Paper presents impact of multidisciplinary approach in treatment of patients with Sotos Syndrome. Design: 36 months old female patient with Sotos syndrome was presented to us three years ago with an atypical development of communication and social interaction, inattentivity, hyperactivity and overall difficulty to manage her. She met diagnostic criteria for atipic childhood autism and specific training for autism was applied. At the age of five years and nine months Stanford Binett test was applied with a result of learning disability and the patient started receiving specific training. Results: Development was shown very quickly, she learned reading and writing, inattentivity and hyperactivity disappeared. Conclusions: Sotos syndrome is syndrome with multiple anomaly and common developmental and behavioral problems. Patients have a high risk of developing ADHD, temper tantrums and present autistic features. Academic difficulties and learning disabilities occur in most of them. Specific cognitive deficit may be present while levels of general intelligence stays unimpaired.
Nano-sized Metal Oxides and Their use as a Surface Disinfectant Against COVID-19: (Review and Perspective)
Authors: Idriss Hajo , M. Habib M. Habib , Alakhras A. I. , El Khair H. M.
Published: January 2023

Contamination of surfaces has long been identified as a significant factor in viral transmission. Therefore, sustained efforts are required to address this issue. This work aims to build a scientific database on nano-sized metal oxides as intelligent materials for surface disinfection against corona viruses, synthesize and characterize nano-sized MgO, and discuss the possibility of using it in virus eradication. The MgO nanoparticle was prepared through the heating method. Meanwhile, XRD diffractometer, Scan electron microscope, and nitrogen adsorption were used to characterize the MgO nanoparticle. The synthesized MgO nanoparticle showed an average crystallite size of 18.55nm, lattice strain 0.0053, surface area 27.56 m2/g and d-spacing 2.1092. The outcomes of this review highlight the advantage and challenges of AgO, CuO, ZnO, TiO2 and MgO nanoparticles and their utilization for surface disinfection against coronaviruses.
Electrochemical and Biological Studies of Synthesized Schiff base and It's Zinc Complex
Authors: Sharma Rekha , Gupta Vinayak , Singh Smriti , Balaee Ishwar Chand , Varshney Sarita
Published: January 2023

The present paper investigated the electrochemical behaviour of Schiff base and its zinc complex at a working electrode by cyclic voltammetry technique. In the phosphate and Britton-Robinson buffers, the electrochemical study of Schiff base was performed within various pH values 5-9. Cyclic voltammograms of the examined Schiff base exhibited irreversible and diffusion controlled waves at different sweep rates, which is associated with the two electron reduction process of azomethine group. The symmetry transfer coefficient (αn), the diffusion coefficient (D01/2) and rate constant (k°f,h) of the reactant species were calculated. Cyclic voltammetric study of zinc complex showed one electron diffusion controlled, quasi-reversible peaks at 50-250 mV/s sweep rates. Antimicrobial study of zinc complex showed that zinc complex found to be more potent than uncoordinated Schiff base.
Colorimetric Detection of Pesticide Residues in Water Using Zinc oxide Nanoparticles
Authors: Mendoza Danilet VI Muncal
Published: January 2023

Zinc oxide nanoparticles were synthesized through green chemistry using lemon extract as reducing agent. The sensitivity of the synthesized nanoparticles against pesticide residues in water was determined. The nanoparticles were characterized based on the absorbance. Characteristic peaks were observed at 281 nm and 328 nm attributed to the exciton absorption peak and maximum absorbance that confirmed the size of the product. The nanoparticles were mixed with different concentration of pesticides in water at varying ratio. The color change was observed in relation to its sensitivity to the solutions. Evident change in color from pale yellow to colorless were observed for both 400 ppb of clothianidin and imidacloprid mixed with ZnO nanoparticles at 1:1 ratio. Absorbance spectra revealed that there is a difference in the interaction of the two pesticides with ZnO nanoparticles. However, same visual color change were observed for both pesticides from pale yellow to colorless. This suggests that the ZnO nanoparticles were not selective as colorimetric detector for clothianidin and imidacloprid.
Antioxidant, Antibacterial and Antifungal Properties of Black Pepper Essential Oil (Piper nigrum Linn) and Molecular Docking and Pharmacokinetic Studies of Its’ Major Component
Authors: Sultana Rajia , Islam Md. Din , Tanjum Fazria , Rahman Mohammad Mostafizur , Haque Md. Aminul
Published: January 2023

The present study aimed to investigate chemical composition of essential oil (EO) from black pepper extract through steam distillation and evaluate by GCMS with in vitro antimicrobial and antioxidant activities and in silico studies. In total, thirteen volatile compounds identified by GCMS analysis. Among them, main components are d-norandrostane (14.874%), Valencene (13.297%), 1H-3a-7-Methanoazulene octahydro-1,9,9-trimethyl-4-methylene- (11.591%), (-)-spathulenol (8.193%), aromandendrene (8.398%), and naphthalenedecahydro-4a-methyl-1-methylene-7-(1-methylethylidene) (7.794%). The EO extracted from black pepper, displayed moderate antibacterial activity against ten bacterial strains (two and eight numbers of Gram-positive and Gram-negative, respectively) compared with Ceftriaxone as standard. In case of antifungal study, the EO exhibited a greater zone of inhibition with 13.7±1.5 mm against Trichodermal harzianum, compare to Amphotericin B as standard (11.7±1.5 mm). The results of antioxidant efficacy of extracted EO revealed good activity with IC50 value 35.83±2.92 μg/mL as compared to standard ascorbic acid (27.34±1.86 μg/mL). In silico studies satisfy the experimental values.
Design and Analysis of Dual Narrow Band MIMO (DNB-MIMO) Antenna for IoT Applications
Authors: Thiruvenkadam Saminathan , Parthasarathy Eswaran
Published: January 2023

A compact DNB-MIMO antenna design and analysis for IoT application was proposed. The antennaradiator consists of 2 L-shaaped quarter-wavelengths and inverted 7-shaped radiators with a microstrip feed line, and partial ground plane with a size of 32 × 15 mm2. This antenna achieves a higher quality factor (Q > 10) and narrow band impedance matching at the central frequencies of 1.8 GHz and 2.4 GHz bands with approximately 8.2% and 6.2% bandwidth respectively. The suitability of the designed antenna for IoT applications is verified through the hosting device model. The proposed 4-port MIMO antenna has an overall size of 60 × 60 ×1.6 mm3, and it is printed on an FR4 substrate. The diversity add comma such as ECC, DG, TARC, MEG, and CCL, are calculated and there values are < 0.19, 9.85 dB, < -25 dB, < -6 dB, < 0.19 bits/Hz/s, respectively, within the limits. The proposed antenna is integrated with the Zigbee module (lowercase) to analyze the performance for IoT applications at 2.4 GHz