bluuebunny/crossref_metadata_2025 huggingface dataset:
El cauce mítico dionisiaco presente en los festivales de música electrónica
Authors: Aguilar Campos Citlaly
Published: June 2020

El ser humano vive y comprende a través de narrativas, el mito es una de ellas ya que funge un papel fundamental en la estructura de nuestro conocimiento. Los mitos prevalecen hasta nuestros días y adquieren nuevos sentidos acorde a la época sociohistórica. A este fenómeno, el antropólogo francés Gilbert Durand lo denomina como cauce mítico.

Uno de estos cauces es el de Dioniso, quien simboliza el vino, la abundancia, el paroxismo salvaje. Desde la década de los 60 con la contracultura y la ruptura de paradigmas, la sociedad se ha volcado en una vorágine de apertura a los tabúes, desencantamiento ante el progreso y cuestionamiento crítico de lo hegemónico. Una de la expresiones artísticas derivadas de esta corriente han sido los festivales de música, los cuales han permitido unir a diferentes generaciones en un espacio común.

Entre estos eventos, destacan los del género electrónico, tales como Tomorrowland, Electric Daisy Carnival (EDC) y Burning Man que -sin ser su principal objetivo- han perpetuado el cauce mítico dionisiaco al fomentar una atmósfera festiva, extática y de espíritu colectivista, siendo tal afirmación la hipótesis a develar a través de los postulados hermenéuticos de G. Durand, M. Beuchot y Rollo May
E-ÖĞRENME İÇİN KRİTİK BAŞARI FAKTÖRLERİ: ALANYAZIN DERLEMESİ
Authors: TAŞBAŞ USTAOĞLU Esra
Published: June 2020

E-öğrenme birçok eğitim programına dâhil edilen teknoloji tabanlı öğrenme trendlerinden biridir. Kişisel faktörlerin, çevresel faktörlerin ve davranışsal faktörlerin birbirlerine olan etkileri, öğrenme sürecini etkilemektedir. E-öğrenme teknik ve sosyal boyutları olan bir süreçtir. Bu bağlamda başarılı bir e-öğrenme süreci için teknik gerekliliklerin yanı sıra sosyal gerekliliklerin de belirlenmesi gerektiği söylenebilmektedir. Çalışma kapsamında, literatür taraması yapılarak, e-öğrenme için kritik başarı faktörleri odağında sunulmuş akademik yayınlar incelenmiştir. E‐öğrenme sürecinde kritik başarı faktörleri ile ilgili olarak literatüre katkı sunan ve yüksek sayıda atıf alan 49 adet birincil kaynak araştırmaya dahil edilmiştir. Araştırma sonucunda, kritik başarı faktörlerini konu alan yayınlarda 104 adet kritik başarı faktörüne ulaşılmıştır. Ulaşılan kritik başarı faktörleri 9 grup altında toplanmıştır. Bir alanyazın derlemesi olan bu çalışma, e-öğrenme projelerinin başarılarını arttırmaya yönelik öneriler sunmaktadır.
EMİR TİMUR’UN YÖNETİM FELSEFESİ VE İLKELERİ
Authors: MAZAK Ali
Published: June 2020

Büyük asker ve siysetçi Emir Timur 14. YY.’da Timurlular İmparatorluğ’unu kurmuş; Asya, Avrupa ve Afrika’da kasırgalar estirmiş; dahi bir asker, müthiş bir siyasetçidir.
Emir Timur, İmar, inşa, iktisat ve siyasetteki başarıları, yenilikleri, üreticiliği tescillenmiştir. Yepyeni, görkemli, görkemli, süslü şehirler kurmuş; bilim adamlarını; islam alimlerini korumuştur. Türk dilini, İslam dinini yaymış; zararlı akımları, karışıklıkları, terörizmi önlemiş; Güven ve istikrar sağlamıştır. Bıraktığı eserler, şehirler göz kamaştırmış ve hayranlık uyandırmıştır. Onun başarılarına avrupa’da “Timur rönesansı” denilmiştir.
Timur, bildiği mahlli Türk-İslam yönetim kültürü ile başarılı bir yönetim ortaya koymuştur.
Bu çalışmada amaç, Emir Timur’un, İdari uygulamalarının ve Tüzükatı’ndaki ilkelerinin geleneksel Türk-İslam yönetim felsefesi açısından değerlendirilmesidir. Araştırma, literatür tarama yöntemiyle yapılmıştır.
Cysts and parasites in an abattoir in Northwest Ethiopia; an urgent call for action on “one health”
Authors: Getahun Desalegn , Van Henten Saskia , Abera Adugna , Senkoro Mbazi , Owiti Philip , Lombamo Fantu , Girma Blen , Ashenefe Baye , Deressa Asefa , Diro Ermias
Published: June 2020

Introduction: Zoonotic parasitic infections such as echinococcosis affect cattle, sheep and goats by lowering quality of meat and hides as well as decreasing milk production. The burden of such diseases among humans is usually underestimated as they are difficult to diagnose. We used abattoir data to estimate the prevalence of zoonotic parasitic infections in animals.

Methodology: Data from 2005-2018 was used from the registry of an abattoir in Northwest Ethiopia. Frequencies, proportions and trends over time were analyzed. Meat inspection was conducted by visualization, palpation and incision.

Results: A total of 58,787 animals were slaughtered in the abattoir during the study period. These included 51,956 (88 %) cattle, 5,890 (10%) sheep and 941 (2%) goats. The detected parasites included Echinococcus in 12,334/58,787 (21%) and Fasciola in 10,551/58,787 (18%) animals. Echinococcus infection was highest among goats (267/941, 28%), followed by cattle (11,591/51,956, 22%) and sheep (476/5,890, 8%). Fasciolosis was detected in 9,877/51,956 (19%) cattle and 178/941 (19%) goats. The number of animals slaughtered strongly decreased over time from 8,405 in 2006 to 1,605 in 2018. However, the proportion of parasitic infections remained high with some fluctuations over the study period.

Conclusions: Echinococcosis and fasciolosis were very common with one out of five animals slaughtered infected. This is of public health concern and needs urgent multi-sectorial efforts from stakeholders at the national and regional level for control of these diseases. One health program approaches may warrant the control of transmission to humans.
Clinical features and treatment outcomes of visceral leishmaniasis patients admitted to three centers in Oromia, Ethiopia
Authors: Tekalign Samson , Adera Cherinet , Den Boer Margriet , Miecha Hirpha , Zewde Ashenafi , Mulugeta Dagnachew , Bishawu Tesfahun , Birru Weyuma , Lema Awoke , Sahlu Tilahun , Alves Fabiana , Manzi Marcel , Takarinda Kudakwashe , Van Griensven Johan
Published: June 2020

Introduction: In three health care facilities in the Oromia region, the aim of this study is to report on 1) the number of VL cases registered over time (2013-2018) and 2) the clinical profile, type of treatment used and response to treatment.

Methodology: A retrospective cohort study was conducted among all VL cases admitted with a diagnosis of VL.

Results: A total of 434 VL cases were registered at the three health facilities, but patient files were available for only 188. Most (51.6%) were children and only three presented with VL relapse. 78 (41.5%) of the 188 patients presented within one month of symptom onset. Concurrent severe acute malnutrition (27.1%), tuberculosis (6.4%) and malaria (6.4%) were common. There were only two cases with HIV coinfection. Fourty-three percent were treated with antimonials, 34% with antimonials combined with paromomycin and 23% with AmBisome. Amongst the 188 patients with patient files there were no deaths and one treatment failure. Six months outcome data were however missing for all. Aggregated data from the 434 VL cases reported three deaths, two treatment failures and one relapse.

Conclusions: Children were most commonly affected, suggesting long-term endemicity. While short-term outcomes are encouraging, long-term follow-up data are required.
Two new reared species of Heteropteron Brullé (Hymenoptera, Braconidae, Cardiochilinae) from northwest Costa Rica, with the first definitive host records for the genus
Authors: Dabek Elizabeth Zhu , Whitfield James B. , Hallwachs Winnie , Janzen Daniel H.
Published: June 2020

Two new Costa Rican species of the braconid parasitoid wasp subfamily Cardiochilinae, Heteropteron kidonoi Dabek & Whitfield and Heteropteron hasegawai Dabek & Whitfield, are described and illustrated from dry forest in the Area de Conservacion Guanacastae, along with data on rearing from their hosts. Heteropteron kidonoi is a solitary endoparasitoid of Stenoma cathosiota (Lepidoptera: Depressariidae) on Roupala montana (Proteaceae), while H. hasegawai is a solitary endoparasitoid of Carthara abrupta (Lepidoptera: Pyralidae) on the same host plant, but typically at slightly higher elevation localities. Diagnostic characters are provided to distinguish these two new species from each other, and also from the three previously decsribed species of Heteropteron. Heteropteron kidonoi and H. hasegawai are the first species of Heteropteron to have any host data, and also are the first to be reported in Costa Rica.
Student Success Centers in Nursing Education: A Case Study Example
Authors: Byrd David A. , Meling Vanessa Bográn
Published: June 2020

Background:

A student success center was established at an academic health science center in an effort to address student performance in a diverse undergraduate nursing program.

Method:

A process for determining student needs and narrowly tailored support interventions was determined through a modified Delphi focus group of students enrolled in a Hispanic Serving Institution's undergraduate nursing program.

Results:

Findings of this study are presented along with the 5-year outcomes associated with the center's efforts. Implementation of these narrowly tailored interventions has led to a considerable improvement in student engagement, as well as higher first-time pass rates on the NCLEX-RN
®
examination by graduates.

Conclusion:

To address the critical shortage of diverse nurses in the United States, schools of nursing must provide all necessary support mechanisms to ensure underrepresented and first-generation college students have every opportunity to graduate and enter the nursing workforce.

[
J Nurs Educ
. 2020;59(7):396–399.]
A Review of Attacks and Countermeasures in Internet of Things and Cyber Physical Systems
Authors: Ponnusamy Vasaki , Regunathan Naveena Devi , Kumar Pardeep , Annur Robithoh , Rafique Khalid
Published: June 2020

The internet usage for commercial and public services has significantly increased over these decades to where security of information is becoming a more important issue to society. At the same time, the number of network attacks in IoT is increasing. These include distributed denial of service (DDOS) attack, phishing, trojan, and others that will cause the network information to not be secure. With the revolution in Industry 4.0 and IoT being the main asset in the Fourth Industrial Revolution, many companies spend thousands or millions to protect their networks and servers. Unfortunately, the success rate to prevent network attack is still not welcoming. The attacks on physical layers, such as jamming, node tampering; link layer, such as collision, unfairness, battery exhaustion; network layer, such as spoofing, hello flood, Sybil attack, wormhole, DOS, DDOS; transport layer, such as flooding, de-synchronization; application layer, such as flooding, are alarming. This chapter reviews attacks and countermeasures.
Cloud-Based IoT Architecture for Green Buildings
Authors: Mathew Rejo Rajan , Kulkarni Vikram
Published: June 2020

Green building (GB) is a game changer as the world is moving towards conserving its resources. Green building management systems available nowadays are too expensive and cannot cater to small or medium-sized buildings. Internet of things-based systems use simple, low-cost sensors, signal processing, and high-level learning methods. Studies on building occupancy and human activities help improve design and push the energy conservation levels. With huge amounts of data and improved learning systems, the impetus is to capture the information and use it well to improve design and justify the green building concept. Cloud-based architecture helps to monitor, capture, and process the data, which acts as input to intelligent learning systems, which in turn help to improve the design and performance of current green building management systems. This chapter discusses role of cloud-based internet of things architecture in improving design and performance of current building management systems.
Pervasive Internet of Things (IoT) for Smart Speakers Discovery and Playback Continuity
Authors: Yichiet Aun , Min Jasmina Khaw Yen , Lee Gan Ming
Published: June 2020

One of the core features of IoT is global device discovery, allowing people to control and manage their connected devices anywhere across the internet. In pervasive IoT, device management becomes seamless and automated using AI for device pairing, content discovery, actions signaling, and command scheduling based on contextual information in a self-managed device paradigm. This chapter presents a novel handoff technique for smart speakers to ensure playback continuity when the users move around in a smart space consisting of multiple discoverable speakers. Current implementations include Spotify Connect, which is service specific, thus lacking in discovery robustness. The proposed handoff discovers at the device level instead of service level to improve device visibility and interoperability through a self-learning topology discovery (SLTD) method. For timely handoff, a rapid preemptive handoff method (RPF) is designed to optimize the TCP handshake mechanism and a content pre-caching technique is used to minimize playback gaps during the soft handoff.
Competitive Cycles in a Hyper-Connected World
Authors: Arbore Alessandro
Published: June 2020

This chapter presents a competitive framework suggesting a circular perspective in analyzing and managing competitive wars in a hyper-competitive and hyper-connected world. The author uses the expression “competitive cycles” to represent a typical journey of a competitive arena. The journey starts with the status quo, characterized by a direct confrontation on specific success factors (War of Position); eventually, this scenario is disrupted by the game-changing strategy of an insurgent (War of Movement). This leads to the next stage of the journey, the War of Imitation, ending up when the new game finally becomes the new status quo, that is, back to the War of Position. Then everything flows, until a new cycle, with its new rules, will start again. The digital tsunami is adding momentum and clock-speed to competitive cycles. In every moment of a firm's life, then, it is vitally important to be fully aware of its different wars. In fact, behind each of them lies distinctive rationales and dynamics, which call for specific strategic approaches.
Business Performance Valuation and Value Creation
Authors: Matias Maria Fernanda , Martins Ana Isabel , Rebelo Sandra
Published: June 2020

The globalization of the economy, the evolution of technology, and the increasing level of competition have imposed constant change to companies, namely on the continuous improvement of their functioning and organization, in the permanent updating of their products, and in the attitude towards the satisfaction of their customers. This pressure for change has led to the emergence of new approaches and management methods. One of these new approaches, called value management, is based on the concept of value, which translates a relationship between the satisfaction of a product or service and the resources necessary for its execution. This study presents the main tools for monitoring performance, highlighting the most expressive indicators of business performance. Before, however, brief reflection will be made on management oriented towards value creation.
Resistance and Protests Through the “Selfie”
Authors: Ibrahim Yasmin
Published: June 2020

Conjoining images of digital self-portraits (i.e., ‘selfies') with protests and resistance recasts the self through new paradigms of enquiry in the social media landscape. The appropriation of digital self-imagery to express protest and partake in social movements and resistance personalises and individuates collective resistance, and, in the process, the ‘self-image' becomes a tool of embodied self-expression as well as solidarity imbuing the ‘self' through new modalities of social relations where the material body is co-opted into a politics of protest without de-centring the self. This chapter examines the phenomenon of selfie-activism within the social media era where the ‘visual' turn of instant imagery lends new forms of the attention economy to protests and campaigns, pulling physically bound protests into virtual and voyeuristic forms online where they perform both to the politics of protest and the demands of semiotic capitalism.
Environmental Campaigns in Traditional and Social Media
Authors: Kuppuswamy Sunitha
Published: June 2020

This chapter describes how the environment is a significant part of today's world. The media has the responsibility of educating the audience about the prevailing environmental issues such as pollution, global warming, and climate change as they threaten humankind and sustainable development. Environmental campaigns play a major role in creating awareness about environmental issues and its adverse effects on people. This chapter examines the content of environmental campaigns in traditional and social media and its impact on the environmental awareness of different cross-cultural sections of people using a survey. The chapter is designed based on the theory of planned behaviour according to which human action is guided by a number of factors. The findings revealed that the campaigns had many positive benefits and a number of factors were influencing the promotion of environmental awareness. The study tested a few factors based on communication theories and discussions were drawn.
Digital Activism
Authors: Howarth Anita
Published: June 2020

Austerity blogs emerged in the context of radical reform of welfare benefits and constrained household budgets. The blogs, written by those forced to live hand-to-mouth, are a hybrid form of digital culture that merge narratives of lived experience, food practices, and political commentary in ways that challenge the dominant views on poverty and hunger. A Girl Called Jack disrupted existing hegemonies by breaking the silence that the stigma of poverty imposes on the impoverished, drew attention to the corporeal vulnerability of hunger, and invited the pity of the reader. In the process, Jack refuted individual-failure accounts of the causes of and challenged notions of welfare dependency by detailing practices to survive and eat healthily on a £10-a-week food budget. This combination of narrative and survival practices resonated powerfully, yet also polarized opinion, drawing attention to social uneasiness over growing levels of poverty and deep divisions over who is responsible for addressing these, and more fundamentally, who the modern poor are and what modern poverty is.
Website-Feature Analysis of Irish Parliamentarians' Performance in Web 2.0 Technologies
Authors: Chen Julie Yuwen , Collins Neil
Published: June 2020

This chapter explores the engagement of Teachta Dála (TDs), members of the Irish lower parliamentary chamber, with Web 2.0 technologies. While conducting the website-feature analysis, the authors looked at three dimensions of each TD's website: information content, interaction tools, and politicians' activities on the web. They found that Irish parliamentarians' usage of the internet is still primarily based on the paradigm of Web 1.0. Perhaps more accurately, Irish politicians' internet usage is in the mode of Web 1.5, in which some interactive and participatory space is generated with the idea that the cyberspace should encourage citizen participation. As conventional variables such as party affiliation and geographic variation still influence TD's website performance, one can conclude that information and communication technologies do not really change the way Irish politics are played. The Irish experience is in line with various other studies, such as in Italy and Finland.
Enhanced Expression of Catalase in Mitochondria Modulates NF-κB–Dependent Lung Inflammation through Alteration of Metabolic Activity in Macrophages
Authors: Han Wei , Fessel Joshua P. , Sherrill Taylor , Kocurek Emily G. , Yull Fiona E. , Blackwell Timothy S.
Published: June 2020

NF-κB is a reduction-oxidation–sensitive transcription factor that plays a key role in regulating the immune response. In these studies, we intended to investigate the role of mitochondrial-derived reactive oxygen species in regulating NF-κB activation by studying transgenic mice that overexpress mitochondrial-targeted human catalase (mCAT). We treated wild-type (WT) and mCAT mice with intratracheal instillation of Escherichia coli LPS and found that mCAT mice had exaggerated NF-κB activation in the lungs, increased neutrophilic alveolitis, and greater lung inflammation/injury compared with WT mice. Additional studies using bone marrow chimeras revealed that this hyperinflammatory phenotype was mediated by immune/inflammatory cells. Mechanistic studies using bone marrow–derived macrophages (BMDMs) showed that LPS treatment induced a sustained increase in NF-κB activation and expression of NF-κB–dependent inflammatory mediators in mCAT BMDMs compared with WT BMDMs. Further investigations showed that cytoplasmic, but not mitochondrial, hydrogen peroxide levels were reduced in LPS-treated mCAT BMDMs. However, mCAT macrophages exhibited increased glycolytic and oxidative metabolism, coupled with increased ATP production and an increased intracellular NADH/NAD+ ratio compared with BMDMs from WT mice. Treatment of BMDMs with lactate increased the intracellular NADH/NAD+ ratio and upregulated NF-κB activation after LPS treatment, whereas treatment with a potent inhibitor of the mitochondrial pyruvate carrier (UK5099) decreased the NADH/NAD+ ratio and reduced NF-κB activation. Taken together, these findings point to an increased availability of reducing equivalents in the form of NADH as an important mechanism by which metabolic activity modulates inflammatory signaling through the NF-κB pathway.
Acute Esophageal Necrosis: A Rare Case of Upper Gastrointestinal Bleeding from Diabetic Ketoacidosis
Authors: Uhlenhopp Dustin J. , Pagnotta Gregory , Sunkara Tagore
Published: June 2020

Acute esophageal necrosis, also known as black esophagus or acute necrotizing esophagitis is a rare condition with roughly 154 cases reported in the literature. This condition is classically diagnosed on its endoscopic findings of a circumferentially black esophagus that abruptly ends at the gastroesophageal junction and transitions to normal gastric mucosa. When present, acute esophageal necrosis potentially signifies a poor prognosis with an overall mortality up to 36%. This case report describes a critically ill patient with multiple comorbidities that was found to have acute esophageal necrosis the entire length of the esophagus secondary to ischemia/hypoperfusion that was caused by diabetic ketoacidosis. The patient had a prolonged hospitalization but was ultimately discharged in stable condition. We also review the literature of this rare esophageal condition.
Hand’s aneurysmal bone cyst: A rare localization. Case report and systematic literature review
Authors: De Vitis Rocco , Vitiello Raffaele , Perna Andrea , Passiatore Marco , Cipolloni Valerio , Pripp Charlotte , Taccardo Giuseppe
Published: June 2020

Aneurysmal bone cysts are benign, rare bony tumours frequently observed among children and young adults principally located in the long bones, pelvis, and spine and rarely in other anatomical district such as the hand. We report the case of a 12-year-old girl with an aneurysmal bone cyst, in active stage, involving the still-open epiphysis of the fourth metacarpal of the right hand, which was in a first time treated by curettage, and 3 months later, occurring a recurrence, by a radically excision of the bone and reconstruction with a graft from the iliac crest. At 10-year follow-up the patient had good cosmetic results and a functioning hand. We also performed a systematic Literature review in order to retrieve the key information regarding: the diagnosis, the clinical features and the treatment.
Shoulder arthroplasty for proximal humerus fractures in the elderly: The path from Neer to Grammont
Authors: Grassi Federico A. , Alberio Riccardo , Ratti Chiara , Surace Michele F. , Piazza Piero , Messinese Piermarco , Saccomanno Maristella F. , Maccauro Giulio , Murena Luigi
Published: June 2020

Shoulder replacement is indicated for the surgical treatment of proximal humeral fractures in elderly patients, when severe comminution and osteoporosis jeopardize the chances of success of any fixation technique. Two different implants are available for this purpose: anatomical hemiarthroplasty (HA) and reverse total shoulder arthroplasty (RTSA). HA for fractures was popularized by Charles Neer in the ‘50s and for several decades remained the only reliable implant for these injuries. However, many authors reported inconsistent results with HA as a consequence of the high rate of tuberosity and rotator cuff failure. In 1987, Paul Grammont designed the first successful RTSA, which was the end result of a long thought process on functional surgery of the shoulder. This implant was initially used to treat cuff tear arthropathy and shoulder pseudoparalysis, but indications have gradually expanded with time. Since RTSA does not rely on a functional cuff for shoulder elevation, it was felt that results in fractures could be improved by this prosthesis. In this study, the salient features of these implants are described to understand the rationale behind both approaches and highlight their pros and cons. Several clinical studies comparing HA vs RTSA for proximal humeral fractures have been published during the last two decades. A literature review is carried out to analyze and compare outcomes of both implants, analyzing clinical results, radiographic findings and complications. The final goal is to provide an overview of the different factors to consider for making a choice between these two prostheses.
Autologous fat transplantation for the treatment of trapeziometacarpal joint osteoarthritis
Authors: Alessandri Bonetti Mario , Rovere Giuseppe , Fulchignoni Camillo , De Santis Vincenzo , Ziranu Antonio , Maccauro Giulio , Pataia Elisabetta
Published: June 2020

Rhizarthrosis is a progressive and disabling pathology affecting the carpometacarpal joint. It’s very common in elderly patients and typically affects postmenopausal women. The diagnosis of rhizarthrosis is mainly made by using different physical examination tests and by evaluating the type of pain and it’s then confirmed by imaging. Over the last few years increasing attention has been devoted to the assessment of new treatment techniques for rhizarthrosis. In this context intra-articular injection of autologous fat grafting for cartilage regeneration has demonstrated promising results in experimental settings as an alternative to open surgery procedures. The aim of this study was therefore to sum up the evidences available so far on autologous fat grafting as an emerging treatment for patients affected by carpometacarpal rizarthrosis. An electronic literature research was carried out on Pubmed, Google Scholars and Cochrane Library using “fat grafting”, “fat graft”, “adipose”, “fat transfer” and “lipoaspirate” as search terms. Authors believe autologous fat grafting is an interesting technique, that hand surgeon should keep in mind especially in early stages of rhizarthrosis were pain has not been solved with non-surgical treatment.
Arthrodesis in the Charcot foot: a systematic review
Authors: Cianni Luigi , Bocchi Maria Beatrice , Vitiello Raffaele , Greco Tommaso , De Marco Davide , Masci Giulia , Maccauro Giulio , Pitocco Dario , Perisano Carlo
Published: June 2020

The Charcot foot is a condition characterized by a progressive derangement of the foot. The type of deformity and patient clinical conditions will lead to the proper surgical approach among exostectomy, arthrodesis (through external and/or internal fixation) and amputation. Many authors report good clinical outcomes performing the arthrodesis in Charcot foot; however, the choice of the most appropriate hardware is still an issue. The aim of this study is to analyze the outcomes of different hardware in midfoot and hindfoot Charcot arthrodesis.
Clinical Trials Facing “Serious Adverse Events” during the Ongoing COVID-19 Pandemic
Authors: Parikh Purvish M , Mehta Prashant , MVT Krishna Kumar , Babu K Govind
Published: June 2020

Aims and Objectives: The ongoing COVID-19 pandemic is having a profound impact on the current clinical trials. We wanted to document the extent of the disruption amongst Indian clinical trial sites. Materials and Methods: We conducted an online survey among oncologists in India with active trials to document their experience with challenges and novel solutions. Results: A total of 60 oncologists replied of which 40 had ongoing trials with open recruitment. Majority of them had stopped screening (55%) and recruitment (62.5%). Almost half of the sites did not have adequate infrastructure (47.5%). Almost all the sites had enrolled patients worried about the impact of COVID-19 on their health outcome (up to 87.5%). The majority of sites had problems with adherence to study schedule of events (87.5%) and administration of study medication (42.5%). A total of 55% of the sites had provided the option of virtual visits. Both investigators (75%) and sponsors/contract research organizations (67.5%) had reached out to each other to maintain study integrity. More than half the centers had difficulty related to adverse events and serious adverse events (documentation and reporting; up to 75%). Discussion: Regulatory authorities in several countries have announced guidelines on the conduct of clinical trials during the COVID-19 pandemic. Whether the disruption lasts for a short or long time, its impact on clinical trials is going to be irreparable.
Pembrolizumab: The Nut Cracker
Authors: Selvarajan Gangothri
Published: June 2020

Anti-programmed cell death-1 (PD-1)/PD ligand-1 immune checkpoint inhibitors (ICIs) are the newest class of drugs approved for various advanced cancers. Pembrolizumab, an anti-PD1 inhibitor, is approved for treating advanced-stage solid malignancies and refractory lymphomas. Recently, it has been approved as tumor agnostic therapy for microsatellite instability-high advanced-stage disease. In all these studies, pembrolizumab has shown dramatic efficacy with lesser Grade3/4 immune-related adverse events. Contemporarily, immunotherapy paved the way for diagnostic assays and immunotherapy-related response assessment criteria definitions. No published Indian experience with ICIs exists other than isolated case reports. This article aims to review on pembrolizumab mechanism, its indications, and safety. The description of other ICIs is beyond the scope of this review.
О числовой полугруппе, порожденной множеством $\{b^{n+1+i}+\frac{b^{n+i}-1}{b-1}\mid i\in\mathbb{N}\}$
Authors: Gu Ze
Published: June 2020

Пусть $b, n$ - положительные целые числа, $b\geq 2$, и $S(b,n)$ - числовая полугруппа, порожденная множеством $\{b^{n+1+i}+\frac{b^{n+i}-1}{b-1}\mid i\in\mathbb{N}\}$. С помощью двух отношений порядка получены формулы для вычисления вложенной размерности, числа Фробениуса, типа и рода $S(b,n)$.
O corpo na história
Authors: Gomes Junior João
Published: June 2020

O objetivo deste artigo é realizar uma sucinta revisão bibliográfica sobre os Estudos Corporais na História, propondo uma reflexão acerca da historiografia do corpo e seus desdobramentos nos estudos de gênero e sexualidades. Percorro variados discursos já produzidos sobre o corpo e seus sentidos em diferentes períodos históricos, demonstrando uma possibilidade de aproximação da historiografia com os Estudos Corporais, além de tecer algumas considerações sobre o trabalho metodológico com fontes e documentos para o corpo.
Los cuerpos en los procesos de formación inicial en educación física
Authors: Ruiz Mariel , Pisano Casala Paula
Published: June 2020

Nos interesan los cuerpos en los procesos de formación docentes en educación física. Cómo se presentan, se observan y se comprenden en dichas experiencias, teniendo en cuenta las prácticas discursivas que operan (didácticas específicas) y los saberes corporales que se producen. Intención que responde a la necesidad de desentrañar los efectos discursivos y de poder en los cuerpos que muy a pesar de las críticas evidenciadas sobre el inmovilismo, el desenfoque y la coherencia entre teoría y prácticas (Cebreiro, 1995) aún se perpetúan.
22.01.2020 Akhisar-Manisa Depremi (Mw 5.5) ve Artçılarının Sismotektonik Analizi
Authors: IRMAK Tahir Serkan , DOĞAN Bülent , YAVUZ Evrim , LİVAOĞLU Hamdullah , SERTÇELİK Fadime
Published: June 2020

Bu çalışmada, 22 Ocak 2020 Akhisar-Manisa (Mw 5.5) depremi ve artçılarının odak mekanizması çözümleri dalga şekli ters çözümü ile elde edilmiş ve buna göre sismotektonik yorum yapılmıştır. Bu amaçla, ana şok ve 35 artçı depremin odak mekanizması çözümleri ISOLA algoritması ile elde edilmiştir. Depremlerin odak mekanizması çözümlerinin çoğunluğu, bölgenin genişleme tektoniği ile uyumlu olup, normal faylanma ve az miktarda doğrultu atım bileşeni olan normal faylanma veya normal faylanma bileşeni olan doğrultu atımlı faylanma özelliğine sahiptir. Analizi yapılan depremlerin odak derinlikleri 4-15 km arasında değişmektedir. Gerilme tensörü ters çözümüne göre; bölge açılma rejiminin (R’=0.75) etkisi altındadır ve KD-BG yönünde açılmaktadır. Açılma hızı 1.3 mm/yıl olarak hesaplanmıştır. Bölgede minimum basınç ekseni (σ3), K21oD olarak yönlenmiştir. Asal gerilme eksenlerinin bölgedeki konumları sırasıyla σ_1, σ_2, ve σ_3 olmak üzere 74o /111o, 16o/291o ve 0o/201o (eğim/azimut) olarak hesaplanmıştır. Bu stres dağılımlarına göre depremlerin üzerlerinde meydana geldiği fay düzlemleri, gerilmeli tektonik kabuk deformasyonunu işaret etmektedir.
İzmir ve Çevresinde Kaydedilen Deprem Dalgalarının Frekans Bağımlı Soğurulması
Authors: KALKAR Berkay , GÖK Elçin
Published: June 2020

Bu çalışmada İzmir ve çevresinde meydana gelen depremlere ait sismik dalgaların frekans bağımlı soğurulmaları analiz edilmiştir. İzmirNET ağı tarafından kayıt edilen, 2008-2019 yılları arasında oluşmuş ve koda magnitüdü 2.3≤MC≤5.5 aralığında değişen 217 adet deprem kullanılmıştır. Sismik dalgaların soğurulma karakteristiği Koda Q ile belirlenmiştir. Koda dalgalarının soğurulması elastik olmayan ortam ve süreksizlikler arasındaki dalga yayınımı ya da heterojenitenin oluşturduğu saçınımdan kaynaklanmaktadır. Çalışmada elde edilen düşük Q0 değerleri aktif sismik bölgeleri temsil etmektedir. Ayrıca, sismik kalite faktörünün frekans bağımlılığı gözlenmiştir. Bu durum litosferin sığ bölgelerindeki heterojenitenin yüksek ve karmaşık bir tektonik yapıya sahip olduğunu göstermektedir. İzmir ve çevresinin karmaşık bir tektonik rejime sahip olması, bulunan düşük Q0 değerlerini destekler ve kabuk yapısındaki ayrışmanın fazla olduğunu gösterir.
Erzurum ve Çevresi İçin Gerilme Tensör ve Coulomb Analizleri
Authors: BAYRAK Erdem , ÖZER Çağlar , PERK Şükran
Published: June 2020

Bu çalışmada Erzurum ve çevresi için gerilme tensör analizi ile hâkim gerilme rejimi araştırılmış, Coulomb gerilme analizi ile gerilme değişimi modellenmiştir. Her iki analiz için veri seti 1966-2019 yılları arasında meydana gelen 58 adet depreme (4.0≤Mw≤6.9) ait odak mekanizması çözümlerinden oluşmaktadır. Gerilme tensör analiz sonuçlarına göre en büyük (σ1) ve en küçük (σ3) asal gerilme eksenleri yatayda, orta asal gerilme (σ2) ekseni ise düşeyde çıkmış ve bu sonucun bölgedeki tektonik rejime bağlı doğrultu atımlı faylar ile uyumlu olduğu görülmüştür. Odak mekanizma çözümlerinden hareketle azimut ve dalım değerleri kullanılarak Coulomb gerilme değişimi elde edilmiştir. Özellikle Kuzey Anadolu Fay Zonu, Horasan-Narman Fayı ve Aşkale Fayında gerilmelerde artış olduğu tespit edilmiştir.
Educación y formación docente para el desarrollo social sostenible: un comentario desde la socioformación
Authors: Arredondo Cortés Sergio Alejandro
Published: June 2020

Sin duda la formación docente tiene una importancia sin precedente en distintos sistemas educativos, en esta misma línea el cuidado del ambiente y el desarrollo social sostenible exigen un lugar dentro de la preparación que deben adquirir los docentes. Uno de los objetivos de esta investigación es analizar la importancia de la formación docente y su papel en la transformación de la gran crisis ecológica por la que atraviesa el planeta. La metodología empleada fue el análisis documental, tomando como punto de partida dos elementos básicos para el desarrollo de este artículo: la formación docente y el desarrollo social sostenible. Los resultados se analizaron desde cuatro grandes temáticas: sociedad del conocimiento, socioformación, desarrollo social sostenible y formación docente, sin duda una asignatura pendiente sigue siendo la formación docente y su impacto en el desarrollo social sostenible. Se concluye que existe la urgencia que las instituciones formadoras de docentes vinculen acciones concretas dentro de su malla curricular que favorezcan el conocimiento y el dominio del desarrollo social sostenible.
Neodesenvolvimentismo ou neoliberalismo: balanço do projeto nacional dos governos do Partido dos trabalhadores / Neodevelopmentalism or neoliberalism: balance of the national project of the Partido dos trabalhadores governmentsNeodesarrollismo o neoliberalismo: balance del proyecto nacional de los gobiernos del Partido de los Trabajadores
Authors: De Oliveira W. Venancio
Published: June 2020

Depois de 12 anos de governos da esquerda Brasil, sob a batuta do Partido dos Trabalhadores (PT) passa por um retrocesso neoliberal. Que ficou destes governos? Realmente conseguiram propor um projeto nacional capaz de desenvolver a economia brasileira e romper com seu atraso histórico. Neste artigo argumentamos, que se aplicou um projeto neodesenvolvimentista trunco, não realizando a totalidade de suas pautas industrializantes, por estar amarrado ao consenso neoliberal-financeiro, que reproduziu o modelo de economia dependente. Esta plataforma foi possível graças ao mecanismo político lulista, que logrou um pacto social politiclassista, numa frágil correlação de força que começou a romper-se com a caída da taxa de lucro em 2012 e com a conflitividade social em 2013. Para tanto, discutimos a natureza deste governo a partir de alguns dados da acumulação capitalista no Brasil para depois à guisa de conclusão definir como fazemos um balanço deste período.
Una propuesta metodológica corporal para el estudio de la migración clandestina desde la antropología / A corporal methodological proposal for the study of clandestine migration from the perspective of Anthropology
Authors: Liberona Concha Nanette , Riquelme Gómez Diego Andrés
Published: June 2020

El artículo tiene como objetivo interpretar la corporalidad de migrantes objetos de tráfico, con énfasis en la experiencia psicosocial de la inmigración clandestina en Chile, con el fin de analizar el impacto de la política migratoria en sus cuerpos. Para esto, primero se plantea la necesidad de una innovación metodológica para el estudio de estas “neo-movilidades alternativas”, en tanto desafío de la antropología de la migración clandestina. Luego se presenta una sistematización de experiencias que conjugan en sus metodologías el arte y la investigación colaborativa con migrantes, entre las cuales está el dispositivo de Teatro Espontáneo, que se propone como intervención en esta metodología corporal. Esta intervención permitió analizar la dimensión subjetiva del tráfico de personas, a partir de tres conceptos: ignominia, racismo y agencia.
The role and place of secondary vocational education in the system of transport education
Authors: Vasiliev A. S. , Razinkin N. E.
Published: June 2020

Secondary vocational education is part of the state system of vocational education in the Russian Federation, which provides training for skilled workers and employees, mid-level specialists. It is these personnel, along with engineers, who are currently most needed both for the development and competitiveness of the transport industry, and for the Russian economy as a whole.

The processes of restructuring the educational space of secondary vocational education in the framework of the implementation of the strategic goals of the development of the transport system of the Russian Federation are considered. The possibilities of the WorldSkills (WS) movement for the innovative development of secondary vocational education are analyzed; advantages and contradictions of the participation of educational organizations in national projects. An active role in the development of the WS movement of the Nonprofit Organization “Association of Colleges and Technical Schools of Transport” is shown.

The author’s view on the possible solutions to the problems identified during the study is given.
WorldSkills Russia — in St. Petersburg College of Railway Transport
Authors: Bykova O. V. , Shekhtman E. I.
Published: June 2020

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Measures to reduce the downtime of a transit wagon with processing
Authors: Grishkova D. Yu.
Published: June 2020

The program for the development of marshalling yards until 2025 assumes the concentration of car traffic processing at large, technically well-equipped marshalling yards. Measures to reduce the downtime of transit cars with processing at the marshalling yard A, aimed at identifying and reducing costs when driving freight trains of increased weight and length on the section A–I1, are relevant from a practical point of view.

One way to reduce the cost of driving freight trains of increased weight and length is to avoid forming 9,000-ton trains. Station A forms trains of increased mass and length, measuring 8000 tons and 9000 tons. This technology has a certain positive effect — an increase in the average weight of the train by 25.5 tons, reducing the need for locomotives and locomotive crews, increasing the carrying capacity of the section, unloading the tracks of the receiving and sending fleet. Also, this technology entails a certain number of difficulties in operation, such as certain requirements for the equipment of locomotives and the use of only three-section locomotives for trains weighing 9,000 tons. This raises the question of the feasibility of driving trains weighing 9,000 tons.
COVID-19 virus pandemia and railways
Authors: Kosmin V. V.
Published: June 2020

The issues of the work of railways in the conditions of the viral pandemic 2019–2020 are considered. The results of the research carried out by a group of the International Union of Railways and the generalization of the experience of railways — members of this organization in the fight against coronavirus in railway transport, both at stations and in trains during the trip, are presented, for both passengers and maintenance personnel. The relevant recommendations of an organizational and technical nature are provided.
Innovations in transport abroad (on the pages of the foreign press)
Authors: Tiverovsky V. I.
Published: June 2020

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Politik Hukum Kelembagaan Pengelolaan Zakat Dalam UU No. 21 Tahun 2008 Dan UU No. 23 Tahun 2011
Authors: Putra Adiyes , Nurnasrina
Published: June 2020

The process of making the Draft Law on Islamic banking and the Draft Management Act on zakat becoming a law that is legal and legal goes through a long process. In the process, there was a tug of war between those who supported the formation of the law and those who disagreed with the issue of Islamic banking and the management of zakat formally regulated in the form of laws. It must be recognized that the formation of laws is influenced by the level of community development, the level of the economy, culture, science and technology, and religious beliefs in a society. Of the 10 factions in the legislature, 9 factions stated their approval of the Draft Law on Sharia banking and the Draft Management Act on zakat being ratified into law, and there was one faction that rejected it namely the F-PDS. Although there was a rejection from 1 faction, the legislative and the President finally passed the Sharia banking Act by enacting Law Number 21 the Year 2008 on Sharia Banking on June 17, 2008, and its promulgation by the President on July 16, 2008. Next, Islamic leaders and observers zakat urge the government to immediately amend Law No. 38 of 1999. At the insistence of that later and the legislature and the government ratified Law Number 23 of 2011 concerning Management of Zakat in place of Law Number 38 of 1999.
Belajar Membaca Al-Quran Dengan Metode Qiroati Di KB Mutiara Insani
Authors: Hasan Hasan
Published: June 2020

This journal aims to provide an overview of learning to read the Qur'an with the Qiroati method carried out at KB Mutiara Insani. This research is a qualitative descriptive study with a percentage. The results of the study were divided into two categories: individual and institutional achievements: Individually: 15 students were only able to reach volume 2 with a mastery level of 33%, 8 KB Mutiara Insani students were only able to volume 3 with a mastery level of 50%, 2 KB Mutiara Insani learners are able to reach volume 4 with a mastery level of 66%, 6 KB Mutiara Insani learners are able to volume 5 with a mastery level of 83%, 10 KB Mutiara Insami learners are able to read the Qur'an until volume 6 (up to the Qur'an) with a level of mastery of 100% with the category of Very Good. As for the target of achieving mastery at the institutional level (KB. Mutiara Insani) 61.59% with the category Less.
Инновационный вектор развития автомобильной промышленности России
Authors: Maksyutina Elena , Golovkin Aleksei
Published: June 2020

Analyzed are the global automobile manufacturing trends and their impact on Russia’s
and Belarus’s automobile industries. The subject of analysis is the innovative process as well as the rate of introducing changes related to the technologies of remotely piloted vehicles. Stated are stagnation processes in passenger cars manufacturing, and the growth of innovative activity of the trucks manufacturing segment, especially in agricultural machine manufacturing. Analyzed are the development issues of PJSC «AVTOVAZ», PJSC «KAMAZ», «Gomselmash» and MTZ-HOLDING
Цифровая синергетика взаимодействия внутригодовой активности экономической деятельности и годовой динамики валового внутреннего продукта
Authors: Novikov Michail
Published: June 2020

According to the results of the decomposition of the observed levels of quarterly GDP
indicators statistically relevant components of its dynamics are identified: the dynamic component of seasonal cyclic nature, the trend-cyclic component, and that of short-term fluctuations. A methodology is suggested for studying the impact of within-year economic activity energy on the dynamics of annual GDP indicators. The research analytics was tested on the actual materials of annual and quarterly indicators of the Gross Domestic Product of the Republic of Belarus over the period of 2009–2017.
Влияние covid-19 на российскую экономику: методологические подходы к оценке на основе межотраслевого баланса
Authors: Bykau Aliaksei , Parkhimenka Uladzimir , Tolkachev Sergey
Published: June 2020

We made an attempt to evaluate the impact of the COVID-19 pandemic on the
economy of Russian Federation, based on estimates of domestic demand decrease for each of the 98 industries (products) identified in the system of input-output tables. The analysis was carried out in the context of identifying two key factors of demand changes: lockdown measures that directly limit domestic demand, as well as global oil prices, leading to a reduction in export income of the economy and a subsequent reduction in demand for goods and services in the domestic market. The obtained quantitative
estimates are presented in the context of selected industries, sectors and the Russian economy as a whole. As a generalized conclusion, it justifies the assessment of the joint effect of lockdown and a decrease in oil exports at about 5% of GDP
Низкооплачиваемые рабочие места в белорусской экономике
Authors: Makovskaya Nataliya
Published: June 2020

The article presents the results of a research of low-paying employment in the national
economy of Belarus. The thresholds for the formation of low-paying jobs and areas of economic activity that accumulate such jobs are specified. Identified are the trends and prospects for the existence of low-paying jobs in the Belarusian economy