bluuebunny/crossref_metadata_2025 huggingface dataset:
Superhydrophobic Coatings on Cellulose‐Based Materials: Fabrication, Properties, and Applications
Authors: Teisala Hannu , Tuominen Mikko , Kuusipalo Jurkka
Published: November 2013

Wettability of a solid surface by a liquid plays an important role in several phenomena and applications, for example in adhesion, printing, and self‐cleaning. In particular, wetting of rough surfaces has attracted great scientific interest in recent decades. Superhydrophobic surfaces, which possess extraordinary water repelling properties due to their low surface energy and specific nanometer‐ and micrometer‐scale roughness, are of particular interest due to the great variety of potential applications ranging from self‐cleaning surfaces to microfluidic devices. In recent years, the potential of superhydrophobic cellulose‐based materials in the function of smart devices and functional clothing has been recognized, and in the past few years cellulose‐based materials have established themselves among the most frequently used substrates for superhydrophobic coatings. In this Review, over 40 different approaches to fabricate superhydrophobic coatings on cellulose‐based materials are discussed in detail. In addition to the anti‐wetting properties of the coatings, particular attention is paid to coating durability and other incorporated functionalities such as gas permeability, transparency, UV‐shielding, photoactivity, and self‐healing properties. Potential applications for the superhydrophobic cellulose‐based materials range from water‐ and stain‐repellent, self‐cleaning and breathable clothing to cheap and disposable lab‐on‐a‐chip devices made from renewable sources with reduced material consumption.
Indefinite Media Based on Wire Array Metamaterials for the THz and Mid‐IR
Authors: Naman Osama T. , New‐Tolley Matthew R. , Lwin Richard , Tuniz Alessandro , Al‐Janabi A. Hadi , Karatchevtseva Inna , Fleming Simon C. , Kuhlmey Boris T. , Argyros Alexander
Published: November 2013

Fibre drawing is used to fabricate indefinite media based on wire array metamaterials. Fibres containing arrays of indium wires embedded in polymer are drawn using an optical fibre draw tower, a technique that is intrinsically scalable to larger‐volume fabrication. During drawing, the surface tension of the liquid indium can result in fluctuations to the wire diameter through the Plateau–Rayleigh instability. This is investigated and minimised through a modification of the draw process to achieve wire diameters as low as 1 micrometer. Such wire array fibres are assembled and characterised as electric metamaterials through the resulting high‐pass filtering behaviour. By controlling the draw ratio, the fibre drawing technique is shown to produce electric metamaterials over a wide range of frequencies, from the THz through to the edge of the mid‐IR.
Nitrogen Dioxide‐Catalyzed Electrophilic Iodination of Arenes
Authors: Ren Yun‐Lai , Shang Huantao , Wang Jianji , Tian Xinzhe , Zhao Shuang , Wang Qian , Li Fuwei
Published: November 2013

Nitrogen dioxide is demonstrated to be an effective catalyst precursor for the iodination of alkoxy‐substituted benzenes and naphthalenes. Different from the transition metal catalysts, nitrogen dioxide can be easily separated from the final products, and is free of heavy metal waste. Although the present catalyst precursor is toxic, it does not stain the final products due to its low‐boiling character. No other reagents apart from 0.5 equiv. of iodine (I2), 6.5 mol% nitrogen dioxide and acetonitrile solvent were used in the iodination, and basically all the iodine atoms in the iodine source were transferred to the iodination products, showing that the presented protocol is highly atom‐economic and practical.

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The TiO2–Catechol Complex: Coupling Type II Sensitization with Efficient Catalysis of Water Oxidation
Authors: Tachan Zion , Hod Idan , Zaban Arie
Published: November 2013

Two main requirements must be fulfilled in order to construct an efficient TiO2‐based photo‐electrochemical water splitting cell. One is the expansion of the cell's spectral response, usually by the attachment of a sensitizing dye monolayer on the surface of the TiO2. The second involves the incorporation of a water oxidation catalyst that reduces the overpotential for the oxygen evolution reaction. These requirements are often achieved by the co‐adsorption of both the dye and the catalyst on the TiO2, or by a covalent attachment of the catalyst to the dye molecule. Here, the possibility to use a single material that acts as a sensitizer and a catalyst is presented. The use of a catechol molecule to form a type II charge transfer complex with TiO2 widens the absorption of the system into the visible region. The TiO2‐catechol complex is highly catalytic toward the oxidation of water to oxygen, reducing the electrocatalytic reaction overpotential by 500 mV compared to bare TiO2. A suggested catalytic mechanism for the water oxidation reaction is described. This methodology opens a new path for type II charge transfer complexes to be utilized as catalysts/light absorbers in water splitting systems based on TiO2 or other metal oxides.
Online prediction of subcutaneous glucose concentration for type 1 diabetes using empirical models and frequency‐band separation
Authors: Zhao Chunhui , Dassau Eyal , Zisser Howard C. , Jovanovič Lois , Doyle Francis J. , Seborg Dale E.
Published: November 2013

Online glucose prediction which can be used to provide important information of future glucose status is a key step to facilitate proactive management before glucose reaches undesirable concentrations. Based on frequency‐band separation (FS) and empirical modeling approaches, this article considers several important aspects of on‐line glucose prediction for subjects with type 1 diabetes mellitus. Three issues are of particular interest: (1) Can a global (or universal) model be developed from glucose data for a single subject and then used to make suitably accurate on‐line glucose predictions for other subjects? (2) Does a new FS approach based on data filtering provide more accurate models than standard modeling methods? (3) Does a new latent variable modeling method result in more accurate models than standard modeling methods? These and related issues are investigated by developing autoregressive models and autoregressive models with exogenous inputs based on clinical data for two groups of subjects. The alternative modeling approaches are evaluated with respect to on‐line short‐term prediction accuracy for prediction horizons of 30 and 60 min, using independent test data. © 2013 American Institute of Chemical Engineers AIChE J 60: 574–584, 2014
Phase II trial of HyperCVAD and Dasatinib in patients with relapsed Philadelphia chromosome positive acute lymphoblastic leukemia or blast phase chronic myeloid leukemia
Authors: Benjamini Ohad , Dumlao Theresa Liu , Kantarjian Hagop , O'Brien Susan , Garcia‐Manero Guillermo , Faderl Stefan , Jorgensen Jeffrey , Luthra Rajyalakshmi , Garris Rebecca , Thomas Deborah , Kebriaei Partow , Champlin Richard , Jabbour Elias , Burger Jan , Cortes Jorge , Ravandi Farhad
Published: November 2013

Dasatinib is a second generation tyrosine kinase inhibitor, with activity in imatinib resistant Ph‐positive ALL. We have treated 34 patients with relapsed Philadelphia chromosome positive acute lymphoblastic leukemia (ALL) (n = 19) or lymphoid blast phase of chronic myelogenous leukemia (CML‐LB) (n = 15) with the combination of dasatinib and the hyperCVAD regimen. Prior regimens included hyperCVAD plus imatinib (n = 11, 4 had transplant in first CR), other combination chemotherapy (n = 12), monotherapy with kinase inhibitors other than dasatinib (n = 9), and investigational agents (n = 2). Pretreatment ABL mutations were noted in 10 patients. The overall response rate was 91%, with 24 patients (71%) achieving complete response (CR), and 7(21%) CR with incomplete platelet recovery (CRp). Two patients died during induction and one had progressive disease. Twenty‐six patients (84%) achieved complete cytogenetic remission after one cycle of therapy. Overall, 13 patients (42%) achieved complete molecular response, and 11 patients (35%) had major molecular response (BCR‐ABL/ABL<0.1%). Nine patients proceeded to allogeneic transplantation. Grades 3 and 4 toxicities included hemorrhage, pleural and pericardial effusions and infections. The median follow‐up for patients with CML‐LB is 37.5 months (range, 7–70 months) with a 3‐year overall survival of 70%; 68% remained in CR at 3 years. For ALL patients, the median follow‐up is 52 months (range, 45–59 months) with a 3‐year survival of 26%; 30% remain in CR at 3 years. The combination of HyperCVAD regimen with dasatinib is effective in patients with relapsed Ph‐positive ALL and CML‐LB. Am. J. Hematol. 89:282–287, 2014. © 2013 Wiley Periodicals, Inc.
Sickle‐cell disease stroke throughout life: A retrospective study in an adult referral center
Authors: Gueguen Antoine , Mahevas Matthieu , Nzouakou Ruben , Hosseini Hassan , Habibi Anoosha , Bachir Dora , Brugière Pierre , Lionnet François , Ribeil Jean‐Antoine , Godeau Bertrand , Girot Robert , Ibrahima Vahid , Calvet David , Galactéros Frédéric , Bartolucci Pablo
Published: November 2013

Strokes are one of the most severe complications of sickle‐cell disease. Most studies have been restricted to children with sickle‐cell disease. To better understand the characteristics and follow‐up of strokes occurring from childhood to adulthood, we undertook a retrospective cohort study of 69 stroke patients among the 2,875 patients consulting at the French Adult Sickle‐Cell Disease Referral Center. Between 1970 and 2008, they had experienced 104 strokes: 80 ischemic, 22 hemorrhagic, and 2 intracranial sinus thromboses. Coma and/or fatal outcomes underscored the severity of strokes in sickle‐cell disease patients. Hemorrhagic strokes occurred mostly in adults and carried a higher risk of death than ischemic stroke. The mechanisms underlying sickle‐cell disease associated strokes were reevaluated and etiologies were determined for first stroke and recurrences, in childhood and adulthood. Sickle‐cell disease vasculopathy concerned only SS patients and remains their most frequent stroke etiology. Cardioembolism, vaso‐occlusive crisis and triggering factors were other etiologies identified in adults. Recurrences occurred in 19 SS patients only after a first ischemic stroke. SC patients' strokes occurred in adulthood and were associated with cardiovascular risk factors. Our findings provide novel information about cerebrovascular pathologies throughout the lives of sickle‐cell disease patients and suggest the need for different diagnostic and therapeutic management approaches in those different settings. Am. J. Hematol. 89:267–272, 2014. © 2013 Wiley Periodicals, Inc.
Ambulatory quality indicators to prevent infection in sickle cell disease
Authors: Beverung Lauren M. , Brousseau David , Hoffmann Raymond G. , Yan Ke , Panepinto Julie A.
Published: November 2013

The purpose of this study was to identify rates of adherence for three outpatient quality indicators noted by Wang et al. (Pediatrics 2011;128:484–493): (1) influenza vaccine, (2) pneumococcal immunizations, and (3) penicillin prophylaxis in patients with sickle cell disease (SCD) in a Medicaid sample. These variables were chosen based on Wang and colleagues' suggestion that these variables are important for the assessment of the quality of care of children with SCD. We hypothesized that the overall rate of adherence would be poor with adults having worse rates of adherence than children. We conducted a retrospective cohort study using the Wisconsin State Medicaid database over a 5‐year period to assess the preventative medication adherence of individuals with SCD. Preventative medication variables in this study included influenza vaccination, pneumococcal immunizations (PCV7, PPV23), and penicillin prophylaxis. As predicted, the 2003–2007 Wisconsin State Medicaid database showed patients with SCD had low adherence in terms of recommended influenza vaccinations (21.58% adherent), PPV23 pneumococcal immunizations (43.47% adherent), and penicillin prophylaxis (18.18% adherent). Pneumococcal immunizations for PCV7 were higher than expected (77.27% adherent). Although children tended to adhere to recommended preventative medications more than adults, overall adherence was low. Although we cannot explain why adherence is low, it is likely due to multiple factors at the patient‐ and provider‐level. We encourage patients and providers to create a partnership to meet adherence recommendations, and we describe our strategies for increasing adherence. Am. J. Hematol. 89:256–260, 2014. © 2013 Wiley Periodicals, Inc.
Family history and clefting as major criteria for CHARGE syndrome
Authors: Hughes Susan Starling , Welsh Holly I. , Safina Nicole P. , Bejaoui Khemissa , Ardinger Holly H.
Published: November 2013

CHARGE syndrome is an autosomal dominant malformation syndrome associated with mutations in CHD7. The condition is typically sporadic with few familial cases reported. The diagnosis of CHARGE syndrome is based on a combination of major and minor criteria comprised of structural and functional abnormalities, most of which are part of the original CHARGE acronym, although additional anomalies have been added. To date, family history has not been considered in the diagnostic criteria. Here we report a family with a previously unreported missense mutation in exon 31 of CHD7, in which family history played a role in the diagnosis of CHARGE syndrome. Given the tremendous phenotypic variability and the dominant nature of CHARGE syndrome, we propose that family history be included as a major diagnostic criterion. A positive family history would include any individual with an apparently isolated unilateral major CHARGE anomaly or someone with a few of the minor features. Our cases support this proposal; had family history not been considered in this case, CHD7 testing might not have been pursued, leading to incomplete medical follow‐up and erroneous genetic counseling. Additionally, with the increased incidence of orofacial clefting in this family, as well as in the literature, we suggest that cleft lip and/or palate be added to the major diagnostic criteria for CHARGE syndrome. © 2013 Wiley Periodicals, Inc.
Predicting primate local extinctions within “real‐world” forest fragments: A pan‐neotropical analysis
Authors: Benchimol Maíra , Peres Carlos A.
Published: November 2013

Understanding the main drivers of species extinction in human‐modified landscapes has gained paramount importance in proposing sound conservation strategies. Primates play a crucial role in maintaining the integrity of forest ecosystem functions and represent the best studied order of tropical terrestrial vertebrates, yet primate species diverge widely in their responses to forest habitat disturbance and fragmentation. Here, we present a robust quantitative review on the synergistic effects of habitat fragmentation on Neotropical forest primates to pinpoint the drivers of species extinction across a wide range of forest patches from Mexico to Argentina. Presence‐absence data on 19 primate functional groups were compiled from 705 forest patches and 55 adjacent continuous forest sites, which were nested within 61 landscapes investigated by 96 studies. Forest patches were defined in terms of their size, surrounding matrix and level of hunting pressure on primates, and each functional group was classified according to seven life‐history traits. Generalized linear mixed models showed that patch size, forest cover, level of hunting pressure, home range size and trophic status were the main predictors of species persistence within forest isolates for all functional groups pooled together. However, patterns of local extinction varied greatly across taxa, withAlouattaandCallicebus molochshowing the highest occupancy rates even within tiny forest patches, whereasBrachytelesandLeontopithecusoccupied fewer than 50% of sites, even in relatively large forest tracts. Our results uncover the main predictors of platyrrhine primate species extinction, highlighting the importance of considering the history of anthropogenic disturbances, the structure of landscapes, and species life‐history attributes in predicting primate persistence in Neotropical forest patches. We suggest that large‐scale conservation planning of fragmented forest landscapes should prioritize and set‐aside large, well‐connected and strictly protected forest reserves to maximize species persistence across the entire spectrum of primate life‐history. Am. J. Primatol. © 2013 Wiley Periodicals, Inc.
Komplexe mit Stickstoffradikalliganden: Einteilung, spektroskopische Eigenschaften, Reaktivität und katalytische Anwendungen
Authors: Olivos Suarez Alma I. , Lyaskovskyy Volodymyr , Reek Joost N. H. , van der Vlugt Jarl Ivar , de Bruin Bas
Published: November 2013

Der vorliegende Aufsatz gibt einen Überblick über die elektronische Struktur, die spektroskopischen Eigenschaften und die (katalytische) Reaktivität von Komplexen mit Stickstoffradikalliganden. Komplexe mit Aminyl‐ ([M(.NR2)]), Nitren/Imidyl‐ ([M(.NR)]) oder Nitridylradikalliganden ([M(.N)]) sind nachweisbare und manchmal auch isolierbare Spezies, die trotz ihres Radikalcharakters oft selektive Reaktionsmuster gegenüber einer Vielzahl organischer Substrate zeigen. Für Komplexe mit Stickstoffradikalliganden wird ein Klassifizierungssystem vorgestellt, das auf ihrer Elektronenstruktur basiert und sie als Einelektronen‐reduzierte Fischer‐Systeme, Einelektronen‐oxidierte Schrock‐Systeme oder Systeme mit (fast) kovalenter M‐N‐π‐Bindung beschreibt. Experimentelle, für die Bestimmung des Aufenthaltsortes des Radikals (d. h. Metall oder Ligand) relevante Ergebnisse werden diskutiert, und aktuelle Beispiele aus der Literatur belegen die Verwendung von Komplexen mit Stickstoffradikalliganden in den (katalytischen) Synthesen verschiedener organischer Stickstoffverbindungen wie Aziridine und Amine. Dieser Aufsatz soll dazu beitragen, die (katalytische) Reaktivität von Stickstoffradikalliganden und ihre Rolle bei der Feinabstimmung der Reaktivität von Koordinationsverbindungen besser zu verstehen.
Clamshell Opening in the Mixed‐Metal Supramolecular Aggregates Formed by Fourfold Reduced Corannulene for Maximizing Intercalated Metal Content
Authors: Filatov Alexander S. , Zabula Alexander V. , Spisak Sarah N. , Rogachev Andrey Yu. , Petrukhina Marina A.
Published: November 2013

The first members of a new class of supramolecular organometallic compounds with mixed‐alkali‐metal cluster cores, LiK5 and Li3K3, sandwiched between two four‐fold reduced corannulene decks are prepared and fully characterized. The triple‐decker supramolecular anions, [(C20H104−)(LiK5)6+(C20H104−)]2− and [(C20H104−)(Li3K3)6+(C20H104−)]2−, illustrate a record ability of bowl‐shaped and highly charged corannulene to provide all its sites, five benzene rings fused to a central five‐membered ring, for binding of six alkali‐metal ions. The previously unseen engagement of the hub‐site of C20H104− in lithium binding is accompanied by unprecedented shifts up to −24 ppm in 7Li NMR spectra. The discussion of product formation mechanism, augmented by calculations, is provided.
Complexes with Nitrogen‐Centered Radical Ligands: Classification, Spectroscopic Features, Reactivity, and Catalytic Applications
Authors: Suarez Alma I. Olivos , Lyaskovskyy Volodymyr , Reek Joost N. H. , van der Vlugt Jarl Ivar , de Bruin Bas
Published: November 2013

The electronic structure, spectroscopic features, and (catalytic) reactivity of complexes with nitrogen‐centered radical ligands are described. Complexes with aminyl ([M(.NR2)]), nitrene/imidyl ([M(.NR)]), and nitridyl radical ligands ([M(.N)]) are detectable and sometimes even isolable species, and despite their radical nature frequently reveal selective reactivity patterns towards a variety of organic substrates. A classification system for complexes with nitrogen‐centered radical ligands based on their electronic structure leads to their description as one‐electron‐reduced Fischer‐type systems, one‐electron‐oxidized Schrock‐type systems, or systems with a (nearly) covalent MN π bond. Experimental data relevant for the assignment of the radical locus (i.e. metal or ligand) are discussed, and the application of complexes with nitrogen‐centered radical ligands in the (catalytic) syntheses of nitrogen‐containing organic molecules such as aziridines and amines is demonstrated with recent examples. This Review should contribute to a better understanding of the (catalytic) reactivity of nitrogen‐centered radical ligands and the role they play in tuning the reactivity of coordination compounds.
Nanopore‐Based Sequencing and Detection of Nucleic Acids
Authors: Ying Yi‐Lun , Zhang Junji , Gao Rui , Long Yi‐Tao
Published: November 2013

Nanopore‐based techniques, which mimic the functions of natural ion channels, have attracted increasing attention as unique methods for single‐molecule detection. The technology allows the real‐time, selective, high‐throughput analysis of nucleic acids through both biological and solid‐state nanopores. In this Minireview, the background and latest progress in nanopore‐based sequencing and detection of nucleic acids are summarized, and light is shed on a novel platform for nanopore‐based detection.
The Cross‐Dehydrogenative Coupling of CH Bonds: A Versatile Strategy for CC Bond Formations
Authors: Girard Simon A. , Knauber Thomas , Li Chao‐Jun
Published: November 2013

Over the last decade, substantial research has led to the introduction of an impressive number of efficient procedures which allow the selective construction of CC bonds by directly connecting two different CH bonds under oxidative conditions. Common to these methodologies is the generation of the reactive intermediates in situ by activation of both CH bonds. This strategy was introduced by the group of Li as cross‐dehydrogenative coupling (CDC) and discloses waste‐minimized synthetic alternatives to classic coupling procedures which rely on the use of prefunctionalized starting materials. This Review highlights the recent progress in the field of cross‐dehydrogenative CC formations and provides a comprehensive overview on existing procedures and employed methodologies.
Polypropylene fibers fabricated via a needleless melt‐electrospinning device for marine oil‐spill cleanup
Authors: Li Haoyi , Wu Weifeng , Bubakir Mahmoud M. , Chen Hongbo , Zhong Xiangfeng , Liu Zhaoxiang , Ding Yumei , Yang Weimin
Published: November 2013

Ultrafine polypropylene (PP) fibers as oil sorbents were fabricated via a needleless melt‐electrospinning device and were characterized by scanning electron microscopy and contact‐angle analysis. PP fibers of various diameters and porosities were obtained by the manipulation of the applied electrical field. The effects of the fiber diameter and porosity on the oil‐sorption capacity and oil‐retention behavior were investigated. The experimental results demonstrate that for fiber diameter on the microscale, the porosity played a paramount role in determining the oil‐sorption capacities. The maximum oil‐sorption capacity of the resulting PP fibers with regard to motor oil and peanut oil were 129 and 80 g/g, respectively; these values were approximately six to seven times that of commercial PP nonwoven fabricated through the melt‐blown method. In addition, even after seven sorption/desorption cycles, the oil‐sorption capacity of the chosen sample was still maintained around 80 g/g, and above 97%, oil could be recovered. This indicated excellent reusability and recoverability. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40080.
Theoretical and practical considerations in electrostatic depositioning of charged polymers
Authors: Zeeb Benjamin , Thongkaew Chutima , Weiss Jochen
Published: November 2013

An interfacial engineering technology, based on the electrostatic deposition of charged polyelectrolytes onto surfaces of oppositely charged templates is reviewed with an emphasis on practical applications in the food, pharmaceutical and personal care industries. On interfaces of disperse systems consecutively deposited polymers provide major advantages in terms of physical and chemical stability of dispersions against superimposed stresses (pH, temperature, ionic strength, freezing, chilling, dehydration, lipid oxidation). The controlled deposition of multiple layers allows for a controlled and triggered release of incorporated functional components. This review highlights the basic principles of the layer‐by‐layer (LbL) electrostatic deposition method as well as some major advantages and drawbacks of this approach. An overview of several systems that can be used as templates for the deposition including emulsion droplets, liposomal vehicles, colloidal aggregates, and planar surfaces is given. Suitable substrates for the deposition are presented with a focus on charged biopolymers such as proteins or polysaccharides since they play an essential role in the formulation and stabilization of food, pharmaceutical and personal care applications. Issues and difficulties associated with implementing the technology on a larger, industrial scale are discussed. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40099.
Synthesis and characterization of poly(ester amides)s with a variable ratio of branched odd diamide units
Authors: Murase Sara K. , Franco Lourdes , del Valle Luís J. , Puiggalí Jordi
Published: November 2013

The synthesis of a series of poly(ester amide)s constituted by glycolic acid, adipic acid, and different ratios of 1,3‐pentanediamine and 1,5‐pentanediamine units was studied and the derived copolymers were characterized. Thermal polycondensation between the potassium adipate salt and the appropriate ratio of N,N′‐bis(chloroacetyl)‐1,3‐pentanediamine and N,N′‐bis(chloroacetyl)‐1,5‐pentanediamine was proved to be effective, proceeded with high yield, and rendered samples with moderate molecular weight for carefully controlled competitive thermal degradation reactions. Physical properties were highly dependent on the final composition. In particular, crystallinity and thermal stability decreased with 1,3‐pentanediamine unit content, that is, with the incorporation of lateral ethyl groups into the main chain. The presence of these units also changed solubility in solvents like methanol and degradability in a protease K enzymatic medium. Specifically, incorporation of 1,3‐pentanediamine units led to a gradual increase in degradability. All poly(ester amide)s were able to establish intermolecular hydrogen bonding interactions, which in semicrystalline samples pointed to typical sheet structures of polyamides according to X‐ray diffraction and infrared spectroscopic data. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40102.
Biodegradable poly (butylene succinate‐co‐cyclohexanedimethylene succinate): Synthesis, crystallization, morphology, and rheology
Authors: Wan Tong , Du Tao , Liao Shuang
Published: November 2013

Poly (butylene succinate‐co‐cyclohexanedimethylene succinate) (PBCSs), which are composed of various amounts of cyclohexanedimethylene succinate (CS) with butylene succinate (BS) were synthesized via polycondensation. The composition of PBCSs was analyzed by a 1H‐nuclear magnetic resonance (1H‐NMR). Crystallization, morphology, and rheological properties of PBCSs were investigated by a polarized optical microscopy (POM), a differential scanning calorimetry (DSC), a X‐ray diffraction (XRD), and a parallel‐plate rheometer (PPR). The studies revealed that the composition of PBCSs played an important role in controlling their properties. Only one Tg can be seen for PBCSs by DSC, which demonstrate they are miscible copolymers. PBCSs exhibited lower crystallization capacity than its homopolyesters either Poly (butylene succinate) (PBS) or poly (cyclohexanedimethylene succinate) (PCS). It also proved that the cyclohexyl group of CHDM not only affected the crystalline formation, but also changed spherulitic morphology during crystallization. The spherulitic size gradually decreased with an increase of CS content. When CS content approached 50 wt %, the crystallization ability reached minimum. By comparing the effect of temperature with shear rate, it concluded that the viscosities of PBCSs were more sensitive to temperature rather than shear rate, and flow activation energies of PBCSs linearly increased with an increase of CS content. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40103.
Investigations on rheological properties and gelation of tasar regenerated silk fibroin solution
Authors: Lakkegowda Yogesha , Ammannappa Raghu , Ananthamurthy Sharath
Published: November 2013

Tasar silk is a variety of non‐mulberry silk indigenous to the Indian subcontinent. We present the measured frequency‐dependent viscoelastic moduli of Tasar regenerated silk fibroin (RSF) solution using optical tweezers at two concentrations (0.16% and 0.25% w/v) and extend these measurements to the low frequency regime using a video microscopy technique. We extend the investigation on the rheological behavior of Tasar RSF for four more RSF concentrations, viz., 0.50%, 1.00%, 2.50% and 5.00% using video microscopy. In all the RSF samples, both storage and loss moduli are found to increase with frequency. At lower frequencies the loss modulus is more than the storage modulus and exhibit similar behavior until a crossover frequency beyond which the storage modulus exceeds the loss modulus at all frequencies. The relaxation time which is inversely related to the crossover frequency is found to rise sharply at 5% w/v, indicating the onset of gelation in the sample. These results are examined in relation to the viscoelastic parameters of mulberry silk, wherein the larger crossover frequencies at the same higher concentrations indicate relaxation times that are an order of magnitude smaller than those measured for Tasar RSF. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci.2014,131, 40104.
Power law approximations of movement network data for modeling infectious disease spread
Authors: Geilhufe Marc , Held Leonhard , Skrøvseth Stein Olav , Simonsen Gunnar S. , Godtliebsen Fred
Published: November 2013

Globalization and increased mobility of individuals enable person‐to‐person transmitted infectious diseases to spread faster to distant places around the world, making good models for the spread increasingly important. We study the spatiotemporal pattern of spread in the remotely located and sparsely populated region of North Norway in various models with fixed, seasonal, and random effects. The models are applied to influenza A counts using data from positive microbiology laboratory tests as proxy for the underlying disease incidence. Human travel patterns with local air, road, and sea traffic data are incorporated as well as power law approximations thereof, both with quasi‐Poisson regression and based on the adjacency structure of the relevant municipalities. We investigate model extensions using information about the proportion of positive laboratory tests, data on immigration from outside North Norway and by connecting population to the movement network. Furthermore, we perform two separate analyses for nonadults and adults as children are an important driver for influenza A. Comparisons of one‐step‐ahead predictions generally yield better or comparable results using power law approximations.
Morphological analysis of the branches of the dorsal pancreatic artery and their clinical significance
Authors: Tsutsumi Masahiro , Arakawa Takamitsu , Terashima Toshio , Aizawa Yukio , Kageyama Ikuo , Kumaki Katsuji , Miki Akinori
Published: November 2013

The dorsal pancreatic artery (DP), characterized by a course that crosses behind the proximal part of the splenic vein. It is regarded as clinically important, providing essential distribution to the pancreas. However, the origin of the DP is extremely variable and therefore cannot provide a sufficient basis for identifying it. The DPs of 11 cadavers were investigated in terms of origin, course and distribution. A total of 45 branches of the DP are classified into seven types on the basis of course and distribution. One of these seven types was consistently observed among the specimens: it ran to the right, passed behind the superior mesenteric vein and anterior surface of the posterior part of the head of the pancreas, and then distributed to the uncinate process and the posterior part of the head of the pancreas. Variations in the branching pattern of the DP can be explained from the following perspective: the consistent branch (#5) is the stem of the DP, and other branches originate from it. It is advisable for surgeons to pay attention to this consistent branch of the dorsal pancreatic artery when performing a pancreaticoduodenectomy. Clin. Anat. 645–652, 2014. © 2013 Wiley Periodicals, Inc.
Feasibility and safety of transfemoral implantation of Edwards SAPIEN XT prosthesis without balloon valvuloplasty in severe stenosis of native aortic valve
Authors: García Eulogio , Martín Patricia , Hernández Rosana , Rodríguez Victor , Fernández Abelardo , Gama Vasco , Almería Carlos , Macaya Carlos
Published: November 2013

Objectives

Balloon valvuloplasty (BV) before transcatheter aortic implantation has been thought to be mandatory before the valve is implanted. We have explored the feasibility and safety of direct implantation of balloon expandable Edwards SAPIEN XT valve without prior balloon dilatation.

Background

Some complications after transcatheter aortic valve replacement (TAVR) have been associated with unwanted effects of BV, mainly the contribution to stroke and severe aortic regurgitation (AR) before the valve is implanted. Direct implantation with a self‐expanding aortic valve has been recently reported.

Methods

From November 2011 to April 2012, ten patients were selected that met the following criteria in the transesophageal echocardiography (TEE): moderate calcification, homogeneous distribution of calcium, symmetrical opening of the valve, and some degree of aortic insufficiency.

Results

All patients had symptomatic aortic stenosis of a native valve and high surgical risk; six patients had the valve mildly calcified, in four patients the degree of calcification was moderate. The native valve was crossed and the prosthetic aortic valve was properly positioned in all cases and implanted in the correct position. No patient underwent post‐dilatation and trivial AR was present in four patients. There were no adverse events (death, need for pacemaker, myocardial infarction, or stroke). At 30 days post‐procedure, all patients were alive and had significant clinical improvement.

Conclusions

Direct implantation of Edwards SAPIEN XT without prior BV in selected cases is feasible and safe. The number of patients in whom this technique would be applicable, and their impact on reducing complications has to be determined. © 2013 Wiley Periodicals, Inc.
A prospective observational multicenter study of balloon angioplasty for the treatment of native and recurrent coarctation of the aorta
Authors: Harris Kevin C. , Du Wei , Cowley Collin G. , Forbes Thomas J. , Kim Dennis W. ,   On Behalf of the Congenital Cardiac Intervention Study Consortium (CCISC)
Published: November 2013

Objectives

Balloon angioplasty (BA) is an important treatment option for coarctation of the aorta. The congenital cardiovascular interventional study consortium (CCISC) represents a multi‐institutional and multi‐national effort to prospectively investigate congenital cardiac interventions. A prospective observational analysis of the efficacy and safety of balloon aortic angioplasty was conducted.

Methods

Data were collected prospectively from 36 CCISC sites from 2004 to 2012. One hundred and thirty patients underwent BA for native (n = 76) and recurrent (n = 54) coarctation. Acute, short‐term, and intermediate outcomes are described for BA performed in the setting of native and recurrent coarctation of the aorta. Outcome measures included residual upper to lower extremity blood pressure gradient (ULG), use of antihypertensive medications, aortic wall injury, reobstruction, and need for reintervention.

Results

There was no procedural mortality. Acutely in native and recurrent coarctation, BA achieved an ULG less than 15 mm Hg in 73–80% and to less than 10 mm Hg in 54–68% of patients, respectively. At intermediate follow‐up, ULG further improved, particularly for those who underwent initial reintervention for recurrent coarctation. No significant differences in aortic wall complications were seen and intervention free survival was similar for both groups. Following angioplasty, there was no significant difference in aortic wall complications; however follow up integrated imaging decreased over time.

Conclusions

BA is a safe and effective treatment for coarctation of the aorta acutely and at intermediate term. Although aortic injury occurred in patients with both native and recurrent coarctation, at intermediate follow‐up, aneurysm was noted more often in those with initial intervention for native coarctation. © 2013 Wiley Periodicals, Inc.
DBD Dyes as Fluorescence Lifetime Probes to Study Conformational Changes in Proteins
Authors: Wawrzinek Robert , Ziomkowska Joanna , Heuveling Johanna , Mertens Monique , Herrmann Andreas , Schneider Erwin , Wessig Pablo
Published: November 2013

Previously, [1,3]dioxolo[4,5‐f][1,3]benzodioxole (DBD)‐based fluorophores used as highly sensitive fluorescence lifetime probes reporting on their microenvironmental polarity have been described. Now, a new generation of DBD dyes has been developed. Although they are still sensitive to polarity, in contrast to the former DBD dyes, they have extraordinary spectroscopic properties even in aqueous surroundings. They are characterized by long fluorescence lifetimes (10–20 ns), large Stokes shifts (≈100 nm), high photostabilities, and high quantum yields (>0.56). Here, the spectroscopic properties and synthesis of functionalized derivatives for labeling biological targets are described. Furthermore, thio‐reactive maleimido derivatives of both DBD generations show strong intramolecular fluorescence quenching. This mechanism has been investigated and is found to undergo a photoelectron transfer (PET) process. After reaction with a thiol group, this fluorescence quenching is prevented, indicating successful bonding. Being sensitive to their environmental polarity, these compounds have been used as powerful fluorescence lifetime probes for the investigation of conformational changes in the maltose ATP‐binding cassette transporter through fluorescence lifetime spectroscopy. The differing tendencies of the fluorescence lifetime change for both DBD dye generations promote their combination as a powerful toolkit for studying microenvironments in proteins.
Cation‐Mediated Conversion of the State of Charge in Uranium Arene Inverted‐Sandwich Complexes
Authors: Camp Clément , Mougel Victor , Pécaut Jacques , Maron Laurent , Mazzanti Marinella
Published: November 2013

Two new arene inverted‐sandwich complexes of uranium supported by siloxide ancillary ligands [K{U(OSi(OtBu)3)3}2(μ‐η6:η6‐C7H8)] (3) and [K2{U(OSi(OtBu)3)3}2(μ‐η6:η6‐C7H8)] (4) were synthesized by the reduction of the parent arene‐bridged complex [{U(OSi(OtBu)3)3}2(μ‐η6:η6‐C7H8)] (2) with stoichiometric amounts of KC8 yielding a rare family of inverted‐sandwich complexes in three states of charge. The structural data and computational studies of the electronic structure are in agreement with the presence of high‐valent uranium centers bridged by a reduced tetra‐anionic toluene with the best formulation being UV–(arene4−)–UV, KUIV–(arene4−)–UV, and K2UIV–(arene4−)–UIV for complexes 2, 3, and 4 respectively. The potassium cations in complexes 3 and 4 are coordinated to the siloxide ligands both in the solid state and in solution. The addition of KOTf (OTf=triflate) to the neutral compound 2 promotes its disproportionation to yield complexes 3 and 4 (depending on the stoichiometry) and the UIV mononuclear complex [U(OSi(OtBu)3)3(OTf)(thf)2] (5). This unprecedented reactivity demonstrates the key role of potassium for the stability of these complexes.
ChemInform Abstract: Zirconium Transition Metal (Poly)antimonides — Synthesis, Characterization and Electrochemical Properties.
Authors: Greiwe Magnus , Krause Maximilian , Osters Oliver , Dorantes Alma , Piana Michele , Nilges Tom
Published: November 2013

Zr2MSb3 (M: Cu, Pd) and Zr3MSb7 (M: Ni, Pd) are prepared by arc melting of the elements followed by annealing at 973 K in evacuated quartz tubes.
ChemInform Abstract: A Promising Mid‐Temperature Thermoelectric Material Candidate: Pb/Sn‐Codoped In4PbxSnySe3.
Authors: Lin Zhi‐Sheng , Chen Ling , Wang Li‐Min , Zhao Jing‐Tai , Wu Li‐Ming
Published: November 2013

Pb‐doped In4‐xPbxSe3 (x = 0.01—0.06) and Pb/Sn‐codoped In4Pb0.01SnySe3 (y = 0.03—0.05) are prepared by solid state reactions of the elements (1223 K, 1 d, annealing at 753 K for 5 d).
ChemInform Abstract: General Observation of Fe3+/Fe2+ Redox Couple Close to 4 V in Partially Substituted Li2FeP2O7 Pyrophosphate Solid‐Solution Cathodes.
Authors: Ye Tian , Barpanda Prabeer , Nishimura Shin‐ichi , Furuta Naoya , Chung Sai‐Cheong , Yamada Atsuo
Published: November 2013

Mixed‐metal Li2MxFe1‐xP2O7 (M: Mn, Co, Mg) cathode materials for lithium ion batteries with a monoclinic structure (space group P21/c) exhibit unusually high Fe3+/Fe2+ redox potentials close to 4.0 V vs Li/Li+.
ChemInform Abstract: Trilacunary Keggin‐Type POMs as Versatile Building Blocks for Lanthanoid Silicotungstates.
Authors: Ni Lubin , Spingler Bernhard , Weyeneth Stephen , Patzke Greta R.
Published: November 2013

The new compounds (IV), (V), (VII), and (IX) are characterized by single crystal XRD, IR, UV/VIS, and photoluminescence spectroscopy, and cyclic voltammetry.
ChemInform Abstract: Synthesis, Structure, and Tungsten NMR Characterization of {SbW9O33}9‐{Mo2O2 S2}2+ Sandwich‐Like Polyoxothiometalates.
Authors: Pilette Marie‐Anne , Floquet Sebastien , Marrot Jerome , Secheresse Francis , Cadot Emmanuel
Published: November 2013

Compounds (V) and (VI) are characterized by single crystal XRD and 183W NMR spectroscopy.
ChemInform Abstract: Electroorganic Synthesis of Esters and Ketones at the Platinum Anode in Aqueous Medium.
Authors: Kumar Sanjeev
Published: November 2013

A simple, eco‐friendly, electrochemical method for the oxidation of primary and secondary alcohols to esters and ketones, resp., using potassium iodide as mediator is given.
ChemInform Abstract: Triphenylene‐Based Tris(N‐Heterocyclic Carbene) Ligand: Unexpected Catalytic Benefits.
Authors: Gonell Sergio , Poyatos Macarena , Peris Eduardo
Published: November 2013

Triphenylene based D3h‐symmetric tris‐NHC‐carbene Pd‐ and Au‐complexes are developed as catalysts for the α‐arylation of propiophenone, Suzuki—Miyaura cross‐coupling, and hydroamination of phenylacetylene.
ChemInform Abstract: Validity of Inorganic Nanosheets as an Efficient Planar Substituent to Enhance the Enantioselectivity of Transition‐Metal‐Catalyzed Asymmetric Synthesis
Authors: Zhao Li‐Wei , Shi Hui‐Min , An Zhe , Wang Jiu‐Zhao , He Jing
Published: November 2013

theoretical and experimental study
ChemInform Abstract: Development of a Generic Activation Mode: Nucleophilic α‐Substitution of Ketones via Oxy‐Allyl Cations.
Authors: Vander Wal Mark N. , Dilger Andreew K. , MacMillan David W. C.
Published: November 2013

A mild method for the generation of intermediary oxy‐allyl cations, allowing for nucleophilic α‐functionalization of ketones is developed.
ChemInform Abstract: In situ Generation of PhI+CF3 and Transition‐Metal‐Free Oxidative sp2 C—H Trifluoromethylation.
Authors: Xu Cong , Liu Jingxin , Ming Wenbo , Liu Yingjie , Liu Jun , Wang Mang , Liu Qun
Published: November 2013

By simple mixing of PhI(OAc)2, TmsCF3 and KF, a hypervalent iodine trifluoromethylating species is formed and directly applied in sp2 C—H trifluoromethylation reactions of ketene dithioacetals and indoles.
ChemInform Abstract: Palladium‐Catalyzed Regio‐, Diastereo‐, and Enantioselective Allylation of Nitroalkanes with Monosubstituted Allylic Substrates.
Authors: Yang Xiao‐Fei , Yu Wei‐Hua , Ding Chang‐Hua , Ding Qiu‐Ping , Wan Shi‐Li , Hou Xue‐Long , Dai Li‐Xin , Wang Pin‐Jie
Published: November 2013

The title reaction affords products with two adjacent chiral centers with excellent selectivities tolerating various substituents at the para, meta, or ortho positions of the phenyl group of allyl (I).
ChemInform Abstract: Efficient Asymmetric Transfer Hydrogenation of N‐Sulfonylimines on Water.
Authors: Wang Lei , Zhou Qi , Qu Chuanhua , Wang Qiwei , Cun Linfeng , Zhu Jin , Deng Jingen
Published: November 2013

The asymmetric transfer hydrogenation of a range of N‐sulfonyl ketimines is achieved with sodium formate and (R,R)‐Ts‐DPEN as the chiral ligand.
ChemInform Abstract: Target‐Oriented Synthesis: Miscellaneous Synthetic Routes to Access 1,4‐Enediones Through the Coupling of 1,3‐Dicarbonyl Compounds with Multiform Substrates.
Authors: Zhu Yan‐ping , Cai Qun , Gao Qing‐he , Jia Feng‐cheng , Liu Mei‐cai , Gao Meng , Wu An‐xin
Published: November 2013

A facile synthesis of enediones is achieved via copper‐catalyzed coupling of 1,3‐dicarbonyl compounds with 2‐haloketones, 2‐hydroxyketones, or methylcarbinols.
ChemInform Abstract: Addressing Challenges in Palladium‐Catalyzed Cross‐Couplings of Aryl Mesylates: Monoarylation of Ketones and Primary Alkyl Amines.
Authors: Alsabeh Pamela G. , Stradiotto Mark
Published: November 2013

For the first time examples of enolate α‐arylation employing aryl mesylate coupling partners and amination of inexpensive phenol derivatives with primary aliphatic amines are developed.
ChemInform Abstract: Highly Stereoselective Olefin Cyclopropanation of Diazooxindoles Catalyzed by a C2‐Symmetric Spiroketal Bisphosphine/Au(I) Complex.
Authors: Cao Zhong‐Yan , Wang Xiaoming , Tan Chen , Zhao Xiao‐Li , Zhou Jian , Ding Kuiling
Published: November 2013

The reaction applies a wide range of alkenes, including cyclic, cis‐ and trans‐1,2‐disubstituted as well as 1,1‐disubstituted ones.
ChemInform Abstract: Desymmetrization of α‐Diimines: Synthesis of New 3‐(Diaziridin‐3‐yl)oxaziridines.
Authors: Aresu Emanuele , Carroccia Laura , Fioravanti Stefania , Pellacani Lucio
Published: November 2013

The synthesis of new heterocyclic compounds (V) characterized by the presence of a diaziridine and an oxaziridine ring directly bound is reported.
ChemInform Abstract: Rhodium‐Catalyzed C3‐Selective Alkenylation of Substituted Thiophene‐2‐carboxylic Acids and Related Compounds.
Authors: Iitsuka Tomonori , Schaal Petra , Hirano Koji , Satoh Tetsuya , Bolm Carsten , Miura Masahiro
Published: November 2013

This regioselective alkenylation affords a wide range of different alkenylated thiophene derivatives and gives also access to the corresponding alkenylated furans, benzofurans, and benzoic acids.
ChemInform Abstract: Synthesis of Dithienopyrrole Derivatives.
Authors: Nenajdenko V. G. , Balenkova E. S. , Emelyanov N. A.
Published: November 2013

All synthesized compounds are novel promising materials for organic semiconductors.
ChemInform Abstract: Synthesis of 2‐Aryl‐3‐trifluoromethylquinolines Using (E)‐Trimethyl(3,3,3‐trifluoroprop‐1‐enyl)silane.
Authors: Omote Masaaki , Tanaka Miyuu , Tanaka Miki , Ikeda Akari , Tarui Atsushi , Sato Kazuyuki , Ando Akira
Published: November 2013

The cyclocondensation reaction to yield quinolines (V) is only suitable for aromatic aldehydes (IV), but not aliphatic aldehydes.
ChemInform Abstract: Robust Cyclometallated Ir(III) Catalysts for the Homogeneous Hydrogenation of N‐Heterocycles under Mild Conditions.
Authors: Wu Jianjun , Barnard Jonathan H. , Zhang Yi , Talwar Dinesh , Robertson Craig M. , Xiao Jianliang
Published: November 2013

The highly selective reduction of a range of N‐heterocyclic compounds as well as imines under mild conditions is reported.
ChemInform Abstract: Iodination of Remote ortho‐C—H Bonds of Arenes via Directed SEAr: A Streamlined Synthesis of Tetrahydroquinolines.
Authors: Nack William A. , He Gang , Zhang Shu‐Yu , Lu Chengxi , Chen Gong
Published: November 2013

Compounds (IV), (IX), and (XIV) contain small amounts of other iodinated products.