bluuebunny/crossref_metadata_2025 huggingface dataset:
ENVIRONMENTALLY FRIENDLY CONSUMER BEHAVIOR OF MILLENNIALS IN KAZAKHSTAN
Authors:   AL-FARABI KAZAKH NATIONAL UNIVERSITY, Rybina Liza , Garkavenko Vladimir , Muratkyzy Kamilla , Kozhakhmetova Dinara
Published: October 2024

This research explores the environmentally friendly consumer behavior of Millennials in Kazakhstan through a quantitative approach. The study targets the pressing issue of sustainable consumption prac-tices among this generation, which holds significant implications for environmental conservation. This study is aimed at exploration of determinants, patterns, and motivations behind environmentally friendly consumer behavior among Millennials in Kazakhstan. It seeks to identify the main factors influencing their choices, the extent to which eco-consciousness guides their decisions, and the influence of external factors, such as marketing strategies and peer influence.This research holds both scientific and practical significance contributing to the existing literature and offering insights into the emerging trends of green consumerism among Millennials in a Central Asian context. Moreover, it provides a quantitative assessment of the factors shaping their eco-friendly consumption, allowing for a nuanced understanding of their behavior. The research methodology in-volves the administration of structured surveys to a representative sample of Millennials in Kazakhstan. Data analysis performed with the use of such statistical methods as regression analysis and hypothesis testing to draw meaningful conclusions.Preliminary findings suggest that while environmental awareness plays a role in Millennials’ con-sumer choices, other factors such as affordability and convenience also significantly influence their be-havior. The research underscores the need for targeted strategies to encourage more sustainable con-sumption practices among this demographic. In conclusion, this research contributes valuable insights into the environmentally friendly consumer behavior of millennials in Kazakhstan, shedding light on the factors driving their choices and serving as a basis for the development and implementation of effective sustainability campaigns. It has the potential to inform policymakers, marketers, and businesses seeking to align their strategies with the preferences of this eco-conscious generation.
The City that does not Sleep: Paris in the Travelogues of Voyagers from Dnieper Ukraine (19th — early 20th Centuries)
Authors: Ivanyuk Oleh , Romanenko Daria
Published: October 2024

The article investigates the records of travellers from Dnieper Ukraine about their visits to Paris in the 19th — early 20th centuries with the aim of reconstructing the image of the French capital. The study is based on travel notes compiled at various times by military personnel, scholars, and individuals involved in the arts. The travelogues are characterized by the subjectivity of descriptions, absence of clear structure, and irregular presentation of data. The author deliberately investigated travel notes created over different decades by individuals from diverse social strata, including M. Bashkirtseva, K. Halahan (senior), O. Krasnokutsky, H. Lukomsky, M. Luchytska, M. Rigelman, K. Skalkovsky, and others. The result of the research is an attempt to form a comprehensive and relatively objective image of the city, emphasizing the changes that occurred over the century. In the course of the investigation, it was established that the attention of travellers from Dnieper Ukraine, who visited Paris, was focused on several aspects related to urban space, including landscape descriptions, the atmosphere of Paris, architectural landmarks, and social phenomena that were less common or entirely absent in the Russian Empire. The transmission of their own romantic fascination with the city was also highlighted in the travelogues. However, there were occasional attempts at scholarly investigations that drew on geographical, historical, ethnographic, and statistical information borrowed by the authors of travel notes from surveys conducted by predecessors, materials from the French press, official publications of government institutions, and local authorities. The images of Paris created by various wanderers from Dnieper Ukraine had a subjective and emotional character. Nevertheless, they allow identifying the main trends in the development of urban space during the specified period and characterizing both external changes and shifts in the social environment that took place over the century.
Kyiv’s Minusnyky: Regime Bans for “Uncertain” Citizens
Authors: Vronska Tamara
Published: October 2024

The article deals with a special category of residents of the capital of Ukraine who were recognized as “socially dangerous” and punished by expulsion from the city, along with a ban on settling in a number of areas of the USSR; as well as with categories of citizens who were banned from living in Kyiv for other reasons. Those expelled by judicial, and more often extrajudicial, authorities received a sentence where the territories prohibited for them were designated as “minus 6”, “minus 12”, and “minus 15” (the numbers meant the number of designated areas, and the word “minus” entered Soviet slang as a root construction of the concept of “minusnyky”, which denoted the community repressed and discriminated against in this way). These and other persons mentioned above had a corresponding entry made in their passports, which made it impossible for them to stay in the capital of the Ukrainian SSR. The purpose of the article is to reveal the Kyivans-minusnyky population, a category of repressed people who for a long time were practically “invisible” to researchers. It also aims to transfer the concept of “minusnyky” with all its narrow and broad connotations from Soviet repressive slang to the academic historical dictionary. The research objectives are to analyze the logic behind the creation of regime prohibitions for “socially dangerous” persons, to highlight certain stages of “cleansing”/“sanitation” of the capital of the Ukrainian SSR and the 50-km zone around it, to consider the circumstances of punishment and discrimination, and to reconstruct the process of adaptation of minuscule population to the regime’s everyday life. The research methodology combines the tools of historical and legal analysis, social anthropology, and the concept of social creation of space. The scientific novelty is to expand the general understanding of political terror and its consequences for the Kyiv community. The atmosphere of regime rule in the capital of Ukraine is analysed as an organic component of the functioning of the totalitarian regime and the punitive and repressive mechanism, the first turns of which occurred simultaneously with the seizure of power by the Bolsheviks. The author traces the progressive growth of the Kyiv minuscule group, the reasons for their acquisition of such a status and strategies for survival in exile. It is proved that in the arsenal of total terror, in addition to the most severe repressions, targeted geographical isolation was actively used against Kyiv residents, which became an effective means of “cleansing” the capital of the Ukrainian SSR from “socially dangerous” persons, a mechanism of social engineering of prolonged effect. The creation of a large detachment of Kyiv’s “minusnyky” was part of the process of atomization of society, construction of spatial hierarchy, and social alienation of people and territories.
The Church Renewal Movement in Ukraine: Based on the Materials of the Kharkiv “Tserkovna Hazeta” (1906)
Authors: Horpynchenko Inna
Published: October 2024

The article describes the church renewal movement, the emergence of which Ukraine at the beginning of the 20th century was a fully natural phenomenon due to the formation of initial liberal processes in society generally caused by the revolution of 1905–1907. It is shown that, not being national-liberation movement, the renewal movement was ideologically based in many respects on the principles of the functioning of the old Orthodox Church in Ukraine (Kyiv Metropolis), which was absorbed by the Moscow Patriarchate in 1686. The move was, in particular, about the independence of the church from the state, canon law, freedom of religion. As evidenced by the materials of the “Tserkovna Hazeta” (“Church Newspaper”), Kharkiv renewalists advocated the need for intra-church reforms in close connection with reforms of a general social nature. Among them were the following: shortening the working day and improving the working conditions of workers, overcoming the lack of land owned by peasants, granting civil rights and freedoms to all categories of the population, banning the death penalty. Rejecting the course of complete separation of the state from the church, the renewalists professed their harmony, the goal of which was declared to be the formation of a “Christian public”, and the means of its creation was to be non-violent “Christian politics”. The short-term existence of the church renewal movement is interpreted first due to the narrow social base of renewal at that time, and second to be a proof of the imperial Russian state’s inadmissibility of any forms of ecclesiastical and generally social liberal ideology.
INDIA IN PAKISTAN’S MILITARY PROPAGANDA: FORMATION OF THE ENEMY IMAGE
Authors:   Prince Alexander Nevsky Military University, Ministry of Defense of the Russian Federation, Golubtsova Ekaterina V.
Published: October 2024

The relations between Pakistan and India have always been hostile. The disagreements between them had a significant impact on the formation of the images of these countries. Pakistani leaders’ perception of India is an example of the enemy image concept. The constant attribution to India of hostile intentions towards Pakistan is the evidence of it. In addition, the religious factor that was basic for the creation of Pakistan, contributed to the division of Muslims and Hindus into “friends” and “foes” and, as a result, added to the opposition between Pakistanis and Indians in the main. The generals who had ruled Pakistan directly for almost 30 years contributed to the creation of the enemy image of India. General Muhammad Ayub Khan was the first to start using the idea of an “aggressive neighbor” in order to unite the Pakistanis. The journals of the Pakistan army, as well as the political autobiographies of the military leaders, indicate that the development of the enemy image of the neighboring state was gradual: the generations of Pakistani officers perceived India differently. However, the tendency to demonize India can be seen as growing within every generation. The image of the neighboring country has a direct impact on the policy of Pakistan towards that country.
A COVID-19-világjárvány magyarországi katona-egészségügyi tapasztalatai
Authors: Fejes Zsolt Dezső , Pereszlényi Csaba István , Csizmár Attila
Published: October 2024

A 2019-ben azonosított új koronavírus okozta világjárvány kezelésével, következményeinek elhárításával, valamint a népegészségügy támogatásával összefüggő szakfeladatok ellátása jelentős kihívások elé állította a Magyar Honvédség (MH) egészségügyi szakállományát. A hosszú hónapokig sajátos környezetben zajló működés eredményeit és tapasztalatait a Magyar Honvédség Egészségügyi Központ Integrált COVID Laboratórium feladatai, valamint a katona-egészségügyi tervezési-szervezési feladatok aspektusán keresztül vizsgáljuk meg.
George Perec’in Uyuyan Adam Adlı Yapıtında Eylemsizliğin Varoluşsal Anlamı
Authors: Pamukcu Gülden
Published: October 2024

Varoluşçuluk, 19. yüzyılda Søren Kierkegaard ve Friedrich Nietzsche gibi filozofların çalışmalarına dayanarak 20. yüzyılda şekillenen bir felsefi akımdır. Bu akım, özellikle II. Dünya Savaşı sonrasında Jean-Paul Sartre, Albert Camus ve Martin Heidegger gibi düşünürler tarafından geliştirilmiştir. Varoluşçuluk, insanın önce var olduğunu ve ardından kendi anlamını, değerlerini ve kimliğini yaratması gerektiğini savunur. Bu felsefe, bireyin özgürlüğünü ve bu özgürlüğün getirdiği sorumlulukları, aynı zamanda anlam arayışını, yabancılaşmayı ve saçma kavramını ön plana çıkarır. Edebiyatta varoluşçuluk ise bireyin varoluşsal sorgulamalarını ve hayatın anlamsızlığı karşısındaki tepkilerini ele alır. Georges Perec'in Uyuyan Adam adlı romanında eylemsizlik temasının varoluşçuluk felsefesi bağlamında nasıl ele alındığını incelemeyi amaçlamayan bu çalışmada nitel çözümleme yöntemi kullanılmış ve varoluşçu edebiyat eleştirisi bağlamında metin incelemesi yapılmıştır. Romanın içeriği, özgürlük ve sorumluluk, anlam boşluğu ve saçma, yalnızlık ve yabancılaşma gibi varoluşçuluğun temel kavramları bağlamında eylemsizlik teması çerçevesinde incelenmiştir. İnceleme sonucunda eylemsizlik, karakterin evrendeki varoluşunu anlamlandırma çabalarının boşunalığı karşısında geliştirdiği bir savunma mekanizması olarak ortaya çıkmıştır. Bulgular, karakterin eylemsizlik yoluyla kendi varoluşsal sorunlarından kaçmaya çalıştığını, ancak bu kaçışın onu daha derin bir yalnızlık ve yabancılaşma içine sürüklediğini göstermektedir. Karakter, kendi özgürlüğünün getirdiği sorumluluklarla yüzleşmektense, eylemsizliği bir kaçış yolu olarak seçmiştir. Bu bulgular, edebiyata varoluşçu bir bakış açısı getirmiş, eylemsizliğin varoluşsal anlamına dair önemli çıkarımlar ortaya koymuştur.
Felaket Sonrası Doğada Kadın: Megan Hunter’ın Sondan Sonra Romanında Ekofeminist İzler
Authors: Baysal Kübra
Published: October 2024

Çağdaş İngiliz yazar Megan Hunter’ın popüler iklim kurgu romanı Sondan Sonra, iklim krizi sonucu sular altında kalan Londra’da doğum yapmayı bekleyen baş karakterin, bebeğiyle birlikte felaketin ortasında verdiği yaşam mücadelesini resmetmektedir. Zarar gören insan-ötesi doğayla kadının bedenler-arası etkileşiminin yansıması olarak, baş karakterin suyunun gelip doğumun gerçekleşmesinin ardından Londra’yı yeniden sel vurur. Yeni doğmuş oğlu ve kocasıyla kuzeydeki dağlara sığınan kadın karakter, doğum öncesinde olduğu gibi sonrasında da cinsiyetçi muamelelere maruz kalarak oğlunun bakımını ve bütün sorumlulukları üstlenir. İskoçya’daki mülteci kampında yalnız bir anne olan O karakteriyle dayanışma içine girerek çocuklarıyla yola koyulurlar. Yolda taciz edilen kadınlar, sonunda güvenli bir noktaya ulaşarak doğa içinde uyumlu bir düzen kurup çocuklarını büyütürler. Yaşanan sel felaketiyle türlü sıkıntılar yaşasalar da erkeklere kıyasla daha güçlü durmuş ve felaketi çocuklarıyla sağlam şekilde atlatırlar. Kaosun ortasında, her şeye rağmen dik duran ana karakter, çocuğuyla arasındaki bağ ve içgüdüleri sayesinde felaketin sona erdiğini hissederek şehre dönüp kayıp kocasıyla kavuşur. Felaketin ortasında yaşanan dram ve zorlukları aktarması nedeniyle karamsar bir tablo çizer gibi görünse de roman aslında, ana karakterin oğluyla kurtuluş mücadelesinin mutlu sonla bitmesiyle okuyucuya umut vadeder. Bu makalede Megan Hunter’ın Sondan Sonra eseri, iklim kurgu romanı olarak ele alınarak doğa ile kadının insan-merkezci düzendeki yeri ekofeminizm ve Antroposen kuramları ışığında irdelenecektir.
Metinlerarası İlişkiler Bağlamında Bir Yenidenyazma Örneği: Rapunzel Masalı
Authors: Bay Gülveren Özlem
Published: October 2024

Kolektif hayal gücünün yansımaları olarak da nitelendirilebilecek olan masallar, toplumların önce söz sonra ise yazı ile nesilden nesile aktardıkları kültürel mirasları arasında yer alır. Önce sözlü kültürden yazıya aktarılarak yeniden yaratılan masallar, günümüzde ise metinlerarasılık bağlamından bir yenidenyazma eylemi ile ikinci bir dönüşüm geçirmektedirler. Metinlerarası yaklaşıma göre, her metin bir yenidenyazmadır. Kullanılan yöntem (açık ya da örtük) hangisi olursa olsun, yeni metin eski metinlerden mutlaka izler taşımaktadır. Söz konusu yenidenyazma, sınırlı bir alıntılama, örtük bir gönderme veya açık bir öykünme olabileceği gibi, bir eserin tamamını dönüştürerek yeniden üretme şeklinde de gerçekleşebilir. Bir metinlerarasılık örneği olarak Gamze Arslan tarafından yenidenyazılan Rapunzel masalının incelendiği bu çalışmada, söz konusu metnin bir yenidenyazma olması sebebiyle metinlerarasılığın temel yöntemi olan karşılaştırma yöntemine başvurulmuştur. Yenidenyazma eyleminin bir dönüşümü de ifade ettiği gerçeğinden yola çıkarak, kaynak masal ile yenidenyazılan masal hem yapı hem de anlam (söylem) boyutunda karşılaştırılmaya çalışılmıştır. İlk aşama için Roland Bathes’ın “Anlatıların Yapısal Çözümlemesine Giriş” te öne sürdüğü model temel alınmış ve kaynak masal ile yenidenyazılan masal, işlev ve eylemler düzeyinde karşılaştırılmıştır. İkinci aşamada ise, yine Roland Bathes’ın göstergebilimsel çözümleme modeli temel alınarak, kaynak masal ile yenidenyazılan masal, içerdikleri ortak göstergeler üzerinden karşılaştırılmıştır. Yapılan incelemeler sonucunda, yenidenyazılan masalın, yapısal olarak da bir dönüşüme neden olduğu ortaya konmuştur. Anlam düzeyinde yapılan karşılaştırmada tüm ortak göstergelere rağmen, onlara yüklenen farklı ve yeni anlamlar nedeniyle, yenidenyazılan masalda bireysel tutum ve davranışlardan çok toplumsal tutum ve davranışların ön planda olduğu görülmüştür. Bu yönleriyle, yenidenyazılan Rapunzel masalı, Grimm Kardeşler’in masalından hem yapısal hem de anlamsal boyutta önemli farklılıklar içermektedir.
The Impact of Religious Officials on Social Life: A Research on Scale Development, Validity and Reliability
Authors: Tuncel Gökhan , Yılmaz Hasan , Göktolga Oğuzhan , Yüzbaşı Bahadir
Published: October 2024

Tradition and religion are two important sources that affect the construction and continuity of social relations throughout history. Before the modern period, when the secular social structure was widely accepted, these two sources served as the primary determinant resource of social ties, sometimes alone and frequently together. This study aims to develop a scale to determine the effect of the level of clerics (imams and muezzins) working under the Presidency of Religious Affairs, the institution authorized to serve religious services in Turkey, on social life. In this context, a survey was conducted with 1208 people in 12 provinces and 42 districts, based on a face-to-face interview method. Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were used to test the reliability and validity of the scale made for this study, in which the universe is taken as a whole. The scale, whose reliability and validity were tested, can be used to assess the impact of religious officials on family, kinship, neighborliness, and work life as well as the impact of religion on state-society relationships.
O EFEITO COLATERAL DO TRATAMENTO DA HIPERCOLESTEROLEMIA: A RABDOMIÓLISE
Authors: riguetti sara lima
Published: October 2024

As estatinas são comumente prescritas para tratar dislipidemias, mas podem causar miopatias e, em casos raros, a sua evolução para a rabdomiólise. Essa classe medicamentosa inibe a síntese de mevalona
OS BENEFÍCIOS MEDICINAIS DA CANABIDIOL EM PACIENTES DIABÉTICOS: UMA REVISÃO INTEGRATIVA
Authors: Machado Keylla Da Conceição , Furtado Danielle Zildeana Sousa , Sousa Márcia de Jesus Mesquita , Morais Washington Kenned Clinton Jhonson Sousa
Published: October 2024

O diabetes mellitus compreende vários distúrbios heterogêneos, que levam a uma condição de hiperglicemia, e o tratamento farmacológico consiste visa a manutenção da glicose no sangue em valores considerados normais. Nesta perspectiva, o presente trabalho tem como objetivo verificar os benefícios medicinais do canabidiol no tratamento de pacientes com diabetes mellitus. Trata-se de uma revisão integrativa da literatura, cuja busca de dados foi realizada nas bases de dados: SciELO, Pubmed/Medline e Science Direct. Na busca inicial, foram identificadas 1.065 pesquisas, destes artigos foram selecionados 10 estudos elegíveis para compor esta revisão. Verificou-se que a maioria dos estudos incluídos se tratou de pesquisas do tipo experimental (70%), com indivíduos com diabetes mellitus do tipo 1 e 2. As doses de canabidiol utilizadas variaram de 0,1 a 100 mg/kg, por um período de 14 dias a 14 meses. Os estudos revisados sugerem que o CBD pode desempenhar um papel significativo no controle dos sintomas e das complicações associadas ao diabetes, incluindo a melhoria do controle glicêmico, redução da resistência à insulina, diminuição da inflamação crônica e proteção contra danos nos órgãos. No entanto, é importante ressaltar que a pesquisa sobre o uso do CBD em pacientes diabéticos ainda está em estágios iniciais, e mais estudos clínicos são necessários para entender completamente seus mecanismos de ação e determinar as doses ideais.
USO INADEQUADO DE METILFENIDATO PARA MELHORIA DO DESEMPENHO ACADÊMICO: UMA REVISÃO INTEGRATIVA
Authors: Oliveira Kelly Beatriz Vieira de , Barbosa Victor Augusto Araújo , Santana Anacleide Paixão de , Castro Silvana Nogueira Barbosa de
Published: October 2024

O Metilfenidato é um fármaco estimulante do sistema nervoso central (SNC), estruturalmente relacionado com as anfetaminas, sendo um dos mais prescritos para o tratamento de transtorno de déficit de atenção e hiperatividade, um transtorno neurobiológico, de causas genéticas, que aparece na infância e frequentemente acompanha o indivíduo por toda a vida. No entanto, o metilfenidato tem sido utilizado para fins não terapêuticos, para produzir euforia e obter aprimoramento cognitivo, reduzindo a sensação de cansaço e aumentando o foco e a atenção. Desta forma, objetiva-se analisar, na literatura nacional e internacional os benefícios e malefícios do uso do metilfenidato para a melhoria do desempenho acadêmico. Trata-se de uma revisão integrativa, em que a busca dos artigos foi realizada nas seguintes bases de dados: Pubmed/Medline, Lilacs e SciELO. Foram incluídas as pesquisas primárias disponíveis integralmente e de forma gratuita, publicadas entre os anos de 2018 a 2023 e nas línguas inglesa e portuguesa. Foram analisados 10 artigos que atendiam a esses critérios. Os resultados evidenciaram que o uso inadequado do metilfenidato em estudantes visa principalmente a melhoria do desempenho acadêmico. No entanto, a vigília que a droga gera pode dar a impressão que a droga ajuda os alunos a se destacarem nos estudos, contudo, o estresse rebote duradouro é uma grande desvantagem sendo responsável por desencadear um ciclo vicioso de dependência. Logo, infere-se que mesmo que o uso do metilfenidato apresente efeitos positivos nos universitários no que diz respeito a melhora no desempenho acadêmico, é notável que malefícios podem prejudicar essa positividade
Câncer de mama masculino: Homem também tem mama!
Authors: Almenara CARDOSO, Stella Silva , Depolo Ana Laura Silveira , Moraes MARTINS, Joyce , Carvalhal GONÇALVES, Arthur , Castro BOTELHO, Eduardo De , Borges RIBEIRO, João Antonio , Oliveira Matheus Teixeira de
Published: October 2024

O presente artigo tem como enfoque o câncer de mama masculino, abordando
as principais noções e concepções, além de como é realizado o diagnóstico, o tratamento
e, principalmente, a prevenção. Neste contexto, cabe destacar que o câncer de mama é
uma doença de múltiplas causas, formada a partir da multiplicação desordenada de células
mamárias, o que leva à formação de um nódulo no tecido mamário capaz de invadir outros
órgãos (metástase à distância) (INCA, 2021). Tal doença é comumente associada apenas
às mulheres, que são o foco das campanhas e da grande maioria dos estudos acadêmicos.
Contudo, no Brasil, 1% do total de casos corresponde ao câncer de mama em homens.
Apesar de o número não parecer expressivo, é indispensável estudar o assunto, visto que,
devido à escassez de informação, tais pacientes acometidos pela doença demoram a
procurar assistência médica por não saberem identificar os sinais e até mesmo pela falta
de conhecimento sobre a possibilidade de homens desenvolverem tal patologia, o que
resulta em um diagnóstico tardio (Telesforo et al., 2021).
Bioquímica dos inibidores de colinesterase na doença de alzheimer e o cuidado com o idoso
Authors: Silva Felipe Beiral Da , Costa ALBANI, Marcelo , Albani Karina Costa , Fully TEIXEIRA, Fábio Luiz
Published: October 2024

Este artigo aborda uma doença neurodegenerativa que afeta cerca de 10% da
população brasileira, a Doença de Alzheimer (DA). É estimado que grande parte da população
portadora da Doença de Alzheimer são idosos, representando o equivalente a 60 a 70% dos
casos e 15 milhões de pessoas em todo o mundo. Inibidores de colinesterase (I-ChE) são
substâncias licenciadas para uso específico da DA e baseia-se na inibição das enzimas
responsáveis por processos catalíticos como, por exemplo, a butilcolinesterase e a acetil. Este
estudo foi realizado através de revisão bibliográfica nas plataformas “SciELO” e “Pubmed”,
buscando trazer um compilado de informações a respeito da Doença de Alzheimer e enfatizar
a importância da família em relação à população idosa. Percebeu-se que o tratamento
farmacológico da doença de Alzheimer pode ser categorizado de acordo com o nível de
progressão da doença e, assim, disponibilizam-se terapias específicas, abordagens profiláticas,
tratamentos sintomáticos e terapêuticas complementares. Concluiu-se que o tratamento da DA,
com fármacos como donepezil, rivastigmina e galantamina não promoverem a cura da doença,
mas possibilitam a preservação e a melhora dos níveis de acetilcolina nas células dos dendritos,
protegendo-as contra a degeneração e morte celular no hipocampo do indivíduo. E assim, são
são preservados os efeitos cognitivos e motores do paciente, bem como a memória, por um
período limitado de tempo. Esses medicamentos são aprovados pelo Serviço Nacional de Saúde
e também são utilizados em outras formas de demência.
COOPERATIVAS MADE IN BRAZIL: TRAMPOLINS DE EXPORTAÇÃO
Authors:   , Vazquez Fabio José Buchedid , Salgues Bárbara Cristina da Paixão , Marques Edivaldo Francisco , Bonafé Simone Cruvinel
Published: October 2024

Projeto apresentado, em grupo, à UNIVERSIDADE PAULISTA como exigência do curso de graduação em Administração, para obtenção do grau de bacharel.

Neste trabalho abordamos o processo de criação das Cooperativas brasileiras, elencando os diversos tipos de Cooperativas, metodologia de trabalho e documentação necessária para se criar uma Cooperativa; apresentando suas variações e como se organizam objetivando ganhar força para concorrer no mercado interno.

Destacaremos principalmente, como as Cooperativas podem se alavancar no mercado internacional, levantando a bandeira do chavão popular “a união faz a força”, ajudando a colocar este país em posição de destaque no cenário mundial como um dos maiores e mais importantes produtores de “commodities” do planeta.

Não obstante, verificaremos os benefícios também para o mercado interno, como importante organização balizadora e geradora de empregos tanto para os grandes centros urbanos, quanto em muitos casos, favorecendo o desenvolvimento de povoados e regiões quase inóspitas da geografia brasileira.

Com este trabalho de pesquisa, buscamos encontrar meios para um maior crescimento de vendas dos produtos “Made in Brazil”, e assim descobrirmos novos caminhos para um desenvolvimento social e econômico sustentável. Esperamos com esta análise científica, contribuir com a nossa despretensiosa parcela, para o crescimento de nossa pátria.
Research of Potential Production 94mTc in Medical Cyclotron
Authors: German KE , Rumyantsev AS , Manukova VA
Published: October 2024

To expand the spectrum of used radiopharmaceuticals, it is proposed to obtain a positron-emitting isotope of technetium 94mTc. The intention of this work is to research the possibility of producing various technetium isotopes on a medical cyclotron. For this purpose, we carried out a series of irradiations of an aqueous solution of molybdenum of natural isotopic composition with protons of 11 MeV energy. After technetium isolation, results were analyzed on a γ-spectrometer. 511 keV gamma-ray line was obtained.
Analysis and Comparison of Social Media Applications Using Forensic Software on Mobile Devices
Authors: Hüseyin Çakır , Hatice Karataş
Published: October 2024

With the integration of mobile systems into daily life, social media applications used especially on Android and iOS platforms contain a significant amount of sensitive information. Social media applications on mobile systems have huge personal and sensitive content. Therefore, it is important to design effective techniques for forensic analysis of social media applications and to detect personal data. In this research, three different paid mobile forensic software and 4 different brands and models of smartphones with different operating systems were used and analyzed. The study shows that private messages, e-mails, time information, shared data, location and time information, and other personal data can be obtained by a forensic expert who performs an examination, and it is seen that one software can access the deleted data, but another software cannot access it. In proportion to the technology used in today’s world, mobile forensics incidents are increasing day by day, and a competitive environment is created among the software used to illuminate these incidents. With this competition, software companies dealing with forensic informatics are trying to obtain different data to illuminate forensic events that may occur due to the active use of social media accounts with the developing technology, and software that does not meet the needs in the face of this situation remains in the background. The criminal elements in the investigation areas of mobile forensics differ daily, and the scope of crimes in the virtual environment is expanding with the developing technology. Therefore, mobile forensic analysis applications should be successful in social media applications other than standard data.
Male Linear Anthropometrics of Selected Nigerian Ethnicities: A Cross - Sectional Analysis
Authors: Michael Okon , HB Fawenhinmi , LE Oghenemavwe , PD Okoh , LK David , CA Oparaocha , CE Ebieto , TA James , AN Maryam , TK Adenowo
Published: October 2024

Introduction: This study aims at evaluating selected linear anthropometrics of three Nigerian ethnic groups to provide baseline data for the creation of 3D Negroid anatomic models. Methods: The research design was a cross-sectional design. The sampling technique was multistage proportionate random sampling. The places of study were Imo, Oyo, and Kano States of Nigeria. The study lasted for one (1) year. Random selection of 1500 adult males from three major tribes (500 Igbo, 500 Yoruba, and 500 Hausa between the ages of 18 and 40 years). Tukey’s Post Hoc test of multiple comparisons was carried out to determine the specific ethnic groups that differ in specific anthropometric parameters. Results: The differences in standing height, arm length, and thigh length across the Hausa, Igbo, and Yoruba ethnic groups are statistically significant (p < 0.05). Conclusion: The study concluded that the Igbo and Yoruba groups had higher standing heights compared to the Hausa group. Arm length was longer in the Igbo and Yoruba groups compared to the Hausa group. However, thigh length was greater in the Hausa group compared to both the Igbo and Yoruba groups, while the Hausa group had longer thigh lengths than both the Igbo and Yoruba groups. The Igbo group displayed the largest arm span, whereas the Hausa group had the widest shoulder breadth. However, the Hausa group had a lower bi-iliac breadth in comparison to the other two ethnic groups.
Противосудорожная активность 6,7-дигидро-5H-пирроло[1,2-a]имидазол-2,3-дикарбоновой кислоты и ее бис-метиламида
Authors: Брусина Мария Александровна , Потапкин Александр Михайлович , Кубарская Лариса Георгиевна , Литасова Елена Викторовна , Пиотровский Левон Борисович
Published: October 2024

Исследован противосудорожный потенциал нового лиганда NMDA-рецептора — 6,7-дигидро-5H-пирроло[1,2-a]имидазол-2,3-дикарбоновой кислоты и одного из ее возможных пролекарств — бис-метиламида на моделях NMDA- и коразол-индуцированных судорог у мышей. Влияние этих соединений на ионные токи, вызванные аппликацией NMDA, исследовано на изолированных нейронах среднего мозга зебраданио методом patch-clamp. На изолированных нейронах показано, что 6,7-дигидро-5H-пирроло[1,2-a]имидазол-2,3-дикарбоновая кислота оказывает блокирующее действие на NMDA-рецептор. Обнаружено, что 6,7-дигидро-5H-пирроло[1,2-a]имидазол-2,3-дикарбоновая кислота и ее бис-метиламид проявляют выраженную противосудорожную активность в отношении NMDA-индуцированных судорог и не активны на модели коразоловых судорог у мышей. Эффективная доза бис-метиламида на модели NMDA-индуцированных судорог в 4,5 раза ниже дозы кислоты.
Диарилизоксазольный аналог комбретастатина A4 — перспективная субстанция для противоопухолевого препарата
Authors: Немцова Елена Романовна , Морозова Наталья Борисовна , Плютинская Анна Дмитриевна , Ноев Алексей Николаевич , Панкратов Андрей Александрович , Демчук Дмитрий В. , Крылов Сергей Сергеевич , Семенов Виктор Владимирович , Шегай Петр Викторович , Каприн Андрей Дмитриевич
Published: October 2024

Разработан и изучен новый аналог комбретастатина A-4 (CA-4) – 4-(4-метоксифенил)-5-(3,4,5-триметоксифенил)-изоксазол (А-123124). Представлены метод его синтеза, физико-химические характеристики, оценка цитотоксической активности на опухолевых клетках человека и мыши, пилотное изучение безопасности и противоопухолевое действие у животных с опухолями человека и мыши. Активность in vitro аналога CA-4 (A-123124) в 10 – 100 раз выше, чем активность соединений сравнения — CA-4Р (ди-Na-соль) и паклитаксела в составе препарата Паклитаксел-Эбеве. В системе in vivo наиболее чувствительны к терапии аналогом CA-4 (A-123124) опухоли толстой кишки человека (HCT-116) и мыши (С-26), торможение роста которых, а также увеличение продолжительности жизни животных c фармакологической поддержкой статистически достоверно отличались от контроля и практически достигали биологически значимых величин. Сочетание воздействия с лучевой терапией значимо повысило продолжительность жизни животных. Сделан вывод о перспективности полученного соединения для дальнейшего изучения с целью разработки лекарственной формы с улучшенной биодоступностью.
Влияние pH раствора на профиль растворения гипромеллозы фталата
Authors: Моисеев Сергей Владимирович , Кузьмина Наталья Дмитриевна , Северинова Елена Юрьевна , Евтеев Владимир Александрович , Бунятян Наталья Дмитриевна
Published: October 2024

Данная работа является продолжением исследования методами ЯМР факторов, влияющих на растворимость гипромеллозы фталата, используемого в качестве основного компонента кишечнорастворимых оболочек, который обеспечивает контролируемое высвобождение действующего вещества твердых лекарственных форм в тонком кишечнике. Цель исследования — изучение методами ЯМР профилей растворения гипромеллозы фталата в водных буферных растворах с pH 4,0, 4,5 и 6,8 с учетом особенностей строения полимера. Исследованы образцы гипромеллозы фталата различных производителей. Для оценки профилей растворения использовали метод 1Н, нестехиометрического состава полимеров – метод 13С, молекулярной массы — метод диффузионно упорядоченной спектроскопии ЯМР. Образцы гипромеллозы фталата с молекулярными массами в диапазоне 19 – 29 кДа и долей фталатных групп 24 – 35 % устойчивы в растворах c pH 4,0 и 4,5 в контролируемом временном диапазоне (10 – 90 мин). В растворе c pH 6,8 при близких значениях долей фталатных групп в молекулах полимеров минимальная растворимость наблюдается у образца с наибольшей молекулярной массой. Образец гипромеллозы фталата массой 16,07 кДа устойчив в растворе с pH 4,0, но растворяется при pH 4,5. Образец гипромеллозы фталата с молекулярной массой 10,79 кДа растворяется при pH 4,0. Таким образом, средняя молекулярная масса гипромеллозы фталата является важным показателем, влияющим на растворимость этого полимера. Полимеры со среднечисловой молекулярной массой не менее 19 кДа устойчивы в средах с pH ≤ 4,5. При значениях молекулярной массы ниже 17 кДа гипромеллозы фталат в этих средах растворяется. Целесообразно при контроле качества гипромеллозы фталата оценивать его среднюю молекулярную массу. В фармакопейные тесты растворения кишечнорастворимых препаратов для лечения кислотнозависимых заболеваний желудка необходимо включать среду растворения с pH 4,5.
A Review of Posthumanist Education Research: Expanded Conceptions of Research Possibility and Responsibility
Authors: Rosiek Jerry Lee , Adkins-Cartee MaryJohn , Donley Kevin , Pratt Alexander B.
Published: October 2024

The influence of posthumanist philosophies—broadly defined to include theories such as Baradian new materialism, Deleuzian assemblage theory, Wynterian counterhumanism, Afro-futurism studies, Indigenous studies theories of nonhuman agency, and others—on education research has been increasing at an exponential rate. This chapter provides a review of this literature organized around the theme of ethical and political responsibility. It compares four genres of posthumanist inquiry: assemblage studies, cartographic studies, diffractive studies, and place-based research. It locates these genres on a continuum from descriptive to enactive forms of inquiry. The review concludes with an examination of three different conceptions of futurity that inform posthumanist reconceptualizations of research responsibility, suggesting research is most powerful when all three are attended to in research designs.
Investigation of the Knowledge Level of Hospital Managers About Strategic Management Tools and Their Use
Authors: Güzel Tülay , Özaydın Özlem
Published: October 2024

Objectives: Effective and efficient implementation of all elements of strategic management is important for health organizations to achieve their future goals. This study aims to examine the knowledge levels of hospital managers about strategic management tools, their usage of these tools, and the priorities and needs in tool selection.
Materials and Methods: The population of the study is the managers working in private hospitals in Antalya Province. 90 managers constitute the sample of the study. The data were collected by face-to-face questionnaire method. The questionnaire includes sociodemographic characteristics form and statements to measure the level of knowledge and use of strategic management tools. Mann Whitney U and Kruskal-Wallis tests were applied to examine the differences between groups, and Spearman Correlation Analysis was applied to examine the relationships between variables. SPSS.25 Package Program was used to analyze the data obtained. Statistical significance was accepted at 0.05 level.
Results: 59% of the participants were female, 63% had a bachelor's degree, and the majority (41%) were middle managers. Those who did not receive managerial training and strategic management training were the majority (54% and 71%, respectively). When the knowledge level of the managers about strategic management tools was analyzed, mission and vision (98.9%) received the highest score, and value chain analysis (73.3%) received the lowest score. It was observed that the priorities of the administrators in the selection of strategic management tools were different between the groups according to gender, level of education, and type of school graduated from. In addition, statistically significant relationships were found between the priorities in the selection of strategic management tools and age, professional experience and years of working in the organization.
Conclusion: Managers have limited knowledge and use of strategic management tools and there are differences in the selection of strategic management tools according to their sociodemographic status.
A unified and entity-centric approach to reduce extra complexity in user modelling and recommender systems
Authors: Beel Joeran
Published: October 2024

The complexity of modern recommender systems stems from the differentiation between users, items, features, and ratings, and the use of techniques like content-based filtering (CBF) and collaborative filtering (CF). This study introduces a unified recommendation model that simplifies these complexities by treating users, items, features, and ratings uniformly, allowing multiple recommendation strategies within a single framework. The model was applied to data from the academic software Docear, which supports research paper management. A sample of 1,000 users was used to compare various approaches, including CBF, CF, and hybrid methods, with the unified model. The results showed the unified model's precision at 5.58%, outperforming the best alternative hybrid model (4.03%). This demonstrates its effectiveness in integrating diverse data types and providing more accurate recommendations. In conclusion, the unified model reduces system complexity while improving precision, making it a promising solution for environments with heterogeneous data. Future research will focus on scalability and optimizing entity weighting to further enhance recommendation accuracy.
How orienting and defense drives oscillatory responses in human visual and motor cortical circuits during viewing of threat pictures: Evidence from ssVEPs and beta band desynchronization.
Authors: Martín Carlota Gil , Blanco Silvia Molina , Sánchez Miriam Díaz , García Sergio Felipe Calvo , del Corral Gabriel Sanchez , del Río Sara Pampín , Moratti Stephan
Published: October 2024

When encountering a potential threat, humans and animals engage in different strategic behaviors, such as orienting and defense, depending on the perceived threat imminence. Orienting has been associated with attentional immobility and heightened 'stimulus intake,' while defense is linked to action preparation and 'sensory rejection'. First, we replicated previous findings showing that humans exhibit either heart rate (HR) acceleration or deceleration in response to the same threat-related picture content. Second, we provide direct evidence that orienting, as indexed by increased HR deceleration, leads to enhanced visuocortical processing of threat-related images, as measured by steady-state visual evoked potentials (ssVEPs). Excitation of motor-relevant cortical circuits, assessed by beta-band desynchronization, was reduced in relation to HR deceleration. Conversely, HR acceleration was associated with a reversed pattern: reduced visual processing and increased excitation of cortical motor circuits, as reflected in ssVEP and beta-band modulations. While self-reported measures of state and trait anxiety, along with valence, arousal, and dominance ratings, did not account for variations in HR response patterns, faster avoidance motor responses were linked to defensive HR changes, and longer avoidance latencies were associated with orienting-like HR changes.
The Advantage of Big Team Science: Lessons Learned from Cognitive Science
Authors: Vaidis David C. , Miranda Jacob Francisco , Buchanan Erin Michelle , Schmidt Kathleen , Yang Yu-Fang , Kowal Marta , Topor Marta , Miller Rachael , Misiak Michał , Wagge Jordan Rose , De Moor Delphine , Altschul Drew , Azevedo Flavio , Boucher Leanne , Doell Kimberly C , Exner Anna , Gjoneska Biljana , Mede Niels G. , Miller Jeremy K. , Mushtaq Faisal , Oliveira Catia Margarida , Paruzel-Czachura Mariola , Pavlov Yuri G. , Protzko John , Seetahul Yashvin , Visser Ingmar , Elsherif Mahmoud Medhat , Pronizius Ekaterina
Published: October 2024

The replication crisis in psychology and related sciences contributed to the adoption of large-scale research initiatives known as Big Team Science (BTS). BTS has made significant advances in addressing issues of replication, statistical power, and diversity through the use of larger samples and more representative cross-cultural data. However, while these collaborations hold great potential, they also introduce unique challenges related to their scale. Drawing on experiences from successful BTS projects, we identified and outlined key strategies for overcoming diversity, volunteering, and capacity challenges. We emphasize the need for the implementation of strong organizational practices and the distribution of responsibility to prevent common pitfalls. More fundamentally, BTS requires a shift in mindset toward prioritizing collaborative effort, diversity, transparency, and inclusivity. Ultimately, we call for reflection on the strengths and limitations of BTS to enhance the quality, generalizability, and impact of research across disciplines.
Automatic Lighting System In Smart Homes For Elderly Based On IOT
Authors: Irianto Kurniawan D. , Sonya Mayla Ayyuni
Published: October 2024

The goal of this research is to create and optimise an autonomous lighting system based on the Internet of Things (IoT) in a smart home, with a focus on improving the comfort and safety of the elderly. The system uses LDR and PIR sensors, as well as embedded IoT devices, to automatically modify illumination in response to changes in light intensity and the presence of occupants. The research results suggest that the created autonomous lighting system works well with its components. Testing shows that the LDR and PIR sensors respond quickly to changes in light and motion, with the light reacting according to the local time set by the RTC. When the LED lights are turned on, the brightness may be changed using the dimmer. The system can also be controlled remotely via a mobile application. During the testing phase, black box testing methodologies were used to optimise the system's functional capabilities, guaranteeing that users may easily monitor the automatic lighting via the application interfaces. As a result, the system has demonstrated that both the hardware and the Blynk application are effective in managing the lights, making it simple for people to manage while giving significant benefits.
Human contact in the digital age: a scarce luxury good?
Authors: Civai Claudia , Caserotti Marta , Skelton Nazia Yasmeen , Carrus Elisa
Published: October 2024

The benefits of digitalisation have been widely embraced, but little is known about one of its downsides, the gradual erosion of human interaction from our lives. What are the psycho-social implications of this? Do people value human contact, and do they value it more when perceived as scarce, effectively turning it into a luxury good? We tested these questions in four pre-registered online studies (N=3521), using hypothetical scenarios encompassing four different domains (education, finance, mental health, and fitness) and a willingness to pay task, where we asked participants how much they were willing to pay for a service, offered either with human contact (e.g., a financial advisor), or fully digital (e.g., an app for financial advice). We found that services offering human contact are valued more than their digital equivalent, and people on higher income are willing to pay more for them, but not for digital; crucially, nudging people to perceive human contact as scarce increased its value, in that people were willing to pay more for it. These findings were replicated within a UK and Italian sample and support our intuition that the move towards digitalisation could introduce a new form of inequality, that of access to human contact.