bluuebunny/crossref_metadata_2025 huggingface dataset:
The phenomenon of military chaplaincy in the spiritual and worldview paradigm of modern Ukraine
Authors: Lomachinska Iryna
Published: January 2023

The article studies the genesis of the military chaplaincy phenomenon in Ukraine. The author analyses the critical models of military chaplaincy in different world armies. The spiritual ministry of the chaplain stands between the Church and the state, which forces them to be in a war-torn world, and at the same time to remain outside the mundane, given the inevitable contradictions between total obedience to the military and humble obedience to God. Religious education is a component of the system of combat and moral and psychological training of military personnel. It is entrusted with the main task - to maintain the troops' high spiritual, patriotic, and combat potential. The main stages of the formation of military chaplaincy in Ukraine in the context of its instantiation are presented in the study. In the national context, the institute of military chaplaincy exists due to the manifestations of the national liberation movement in terms of military threats, forming the image of the chaplain as not only a spiritual but a deeply patriotic personality. It is defined that a robust challenge in the formation of the national military chaplaincy was the war of Russia against Ukraine, which has mobilised the internal potential of active cooperation of state military and religious institutions in the legislative and regulatory framework of military chaplains. The article describes the peculiarities of attracting positive world experience of military chaplaincy. The relevance and novelty of the study are explained by the involvement of a systematic approach that makes it possible to analyse the formation of domestic military chaplaincy in the context of applying positive world experience and preserving its national specificity, focused on the ideological foundations of moral and patriotic education of military personnel. The main directions of religious organisations' activities in military structures are cult and worship, psychological and rehabilitation, ideological and patriotic, spiritual and moral, and motivational and social. It is found that the importance of the global challenges facing the Ukrainian state and its Armed Forces requires military chaplains not only to perform religious functions but, above all, to ensure the high moral qualities of service members, the formation of civic duty to protect the state, to foster the spirit of patriotism, brotherhood, and mutual respect.
The dynamics of intra-Orthodox relations in Ukraine in the situation of the russian-Ukrainian war
Authors: Deinega Evgeniy
Published: January 2023

The article examines the changes in the Orthodox world caused by Russia’s full-scale military invasion of Ukraine. Considerable attention is paid to the geographical location of the Ukrainian state at the crossroads of East and West, which determines the specificity of geopolitical and religious processes in the region. Attention is focused on the historical context of the development of Ukrainian Orthodoxy, the meaning of the concept of “canonical territory”, the attitude of former empires to lost territories is considered; prospects for further dialogue between Ukrainian Orthodox churches are outlined. The process of formation of the national mentality of Ukrainians and thus the formation of a single political and spiritual space, the features of which are a reflection of the dominant national type, is considered. The geopolitical confrontation between Russia and the Western world, whose technological parity stimulates ideological confrontation, and which is often broadcast by Russia through religious narratives, is highlighted. The study compares the position and perception of the russian federation regarding the spiritual environment of Ukraine with the real self-perception of the Ukrainian clergy and believers. The rhetoric of the highest church leadership of Russia at the beginning of the military intervention, as well as the reaction of representatives of the local church and flock to it, is critically evaluated. Attention is paid to the reaction of foreign churches to the events in Ukraine. The problem of the transition of Ukrainian dioceses under the jurisdiction of the Russian Orthodox Church in the occupied territories is highlighted. The materials of the article are aimed at forming a comprehensive idea of the recent history of Ukraine and its Church.
A New Option for Pain Prevention Using a Therapeutic Virtual Reality Solution for Bone Marrow Biopsy (REVEH Trial): Open-Label, Randomized, Multicenter, Phase 3 Study
Authors: Le Du Katell , Septans Anne-Lise , Maloisel Frédéric , Vanquaethem Hélène , Schmitt Anna , Le Goff Marielle , Clavert Aline , Zinger Marie , Bourgeois Hugues , Dupuis Olivier , Denis Fabrice , Bouchard Stéphane
Published: January 2023

Background

Evidence regarding the analgesic effect of distraction through immersion in virtual reality (VR) for care-induced pain has been documented in several phase 2 trials, but comparison with standard treatments in large, randomized studies is needed.

Objective

In this open-label, multicenter, randomized, phase 3 trial, we evaluated the safety and efficacy of a novel VR therapy solution for distraction in the context of bone marrow biopsy.

Methods

Bliss is a VR software with 4 imaginary interactive environments in 3 dimensions with binaural sound (head-mounted display). Efficacy regarding pain intensity was evaluated using a visual analog scale (VAS; score from 0 to 10) immediately after the biopsy. Secondary end points were anxiety and tolerance. Modified intention-to-treat analysis was performed.

Results

Overall, 126 patients with previously documented untreated or suspected malignant hemopathy between September 6, 2018, and May 18, 2020, were randomly assigned in a 1:1 ratio to receive pain prevention with a mixture of nitrous oxide/oxygen (MEOPA; n=63) or VR (n=63) before and during the bone marrow biopsy. We excluded 8 patients from the final analysis (3 in the MEOPA group and 5 in the VR group). All patients received local anesthesia (lidocaine) before biopsy. Follow-up was limited to 1 month after the biopsy. Participants’ median age was 65.5 (range 18-87) years, and 54.2% (64/118) of patients were male. The average pain intensity was 3.5 (SD 2.6, 95% CI –1.6 to 8.6) for the MEOPA group and 3.0 (SD 2.4, 95% CI –1.7 to 7.7) for the VR group, without any significant differences in age, sex, center, and hemopathy (P=.26). Concerning anxiety, 67.5% (79/117; fear of pain questionnaire) of the patients were afraid before the biopsy, and anxiety scores were moderate to very high in 26.3% (30/114; revised Spielberger State-Trait Anxiety Inventory questionnaire) of the patients before the biopsy and 9.0% (10/114) after the biopsy for all patients, without a significant difference between the 2 groups (P=.83). Immersion in VR was well tolerated by the majority (54/57, 95%) of patients in the VR group.

Conclusions

The intensity of pain did not significantly differ between both arms. VR was well tolerated, and the satisfaction of patients, nurses, and physicians was very high. VR could be an alternative treatment in case of contraindication or intolerance to MEOPA.

Trial Registration

ClinicalTrials.gov NCT03483194; https://clinicaltrials.gov/ct2/show/NCT03483194
Effectiveness of Digital Guided Self-help Mindfulness Training During Pregnancy on Maternal Psychological Distress and Infant Neuropsychological Development: Randomized Controlled Trial
Authors: Zhang Xuan , Li Yang , Wang Juan , Mao Fangxiang , Wu Liuliu , Huang Yongqi , Sun Jiwei , Cao Fenglin
Published: January 2023

Background

Maternal psychological distress during pregnancy is associated with unfavorable outcomes in infants. Mindfulness-based interventions (MBIs) can effectively alleviate psychological distress, but there are often barriers to the access of face-to-face interventions.

Objective

This study aimed to investigate the effectiveness of a digital guided self-help (GSH) MBI (GSH-MBI) in reducing maternal psychological distress and improving infant neuropsychological performance.

Methods

This was a randomized controlled trial. We recruited 160 women who were 12 to 20 weeks pregnant and exhibited psychological distress. We randomized them into a digital GSH-MBI group and a control group (usual perinatal care). The digital GSH-MBI consisted of a 6-week intervention through a WeChat mini program, with a daily reminder sent to the participants by a research assistant via WeChat. The primary outcomes consisted of maternal psychological distress, including depression, anxiety, and pregnancy-related anxiety symptoms, which were assessed at 6 time points from baseline to 6 months post partum (only pregnancy-related anxiety symptoms were assessed 3 times during pregnancy). The secondary outcomes were infant neuropsychological outcomes, including temperament and developmental behaviors, which were assessed at 6 weeks and 6 months post partum.

Results

Compared with the control group, the digital GSH-MBI group showed a significant reduction in depression, anxiety, and pregnancy-related anxiety symptoms. In addition, the scores of the digital GSH-MBI group were lower than those of the control group for the 3 types of infant temperament at 6 weeks post partum, including quality of mood, distractibility, and adaptability.

Conclusions

Digital GSH-MBIs are effective in alleviating psychological distress among pregnant women and protecting infant outcomes.

Trial Registration

Chinese Clinical Trial Register ChiCTR2000040717; https://www.chictr.org.cn/showproj.aspx?proj=65376
The Use of Digital Technology for COVID-19 Detection and Response Management in Indonesia: Mixed Methods Study
Authors: Nur Aisyah Dewi , Lokopessy Alfiano Fawwaz , Naman Maryan , Diva Haniena , Manikam Logan , Adisasmito Wiku , Kozlakidis Zisis
Published: January 2023

Background

The COVID-19 pandemic has triggered a greater use of digital technologies as part of the health care response in many countries, including Indonesia. It is the world’s fourth-most populous nation and Southeast Asia’s most populous country, with considerable public health pressures.

Objective

The aim of our study is to identify and review the use of digital health technologies in COVID-19 detection and response management in Indonesia.

Methods

We conducted a literature review of publicly accessible information in technical and scientific journals, as well as news articles from September 2020 to August 2022 to identify the use case examples of digital technologies in COVID-19 detection and response management in Indonesia.

Results

The results are presented in 3 groups, namely (1) big data, artificial intelligence, and machine learning (technologies for the collection or processing of data); (2) health care system technologies (acting at the public health level); and (3) COVID-19 screening, population treatment, and prevention population treatment (acting at the individual patient level). Some of these technologies are the result of government-academia-private sector collaborations during the pandemic, which represent a novel, multisectoral practice in Indonesia within the public health care ecosystem. A small number of the identified technologies pre-existed the pandemic but were upgraded and adapted for current needs.

Conclusions

Digital technologies were developed in Indonesia during the pandemic, with a direct impact on supporting COVID-19 management, detection, response, and treatment. They addressed different areas of the technological spectrum and with different levels of adoption, ranging from local to regional to national. The indirect impact of this wave of technological creation and use is a strong foundation for fostering future multisectoral collaboration within the national health care system of Indonesia.
Effects of Greenness on Myopia Risk and School-Level Myopia Prevalence Among High School–Aged Adolescents: Cross-sectional Study
Authors: Zhang Chang , Wang Cheng , Guo Xin , Xu Huiyu , Qin Zihao , Tao Liyuan
Published: January 2023

Background

Myopia is a serious public health issue. High school–aged adolescents in Beijing have an alarming prevalence of myopia. Therefore, determining myopia protective factors is essential. Green space has a certain association with myopia protective factors that can protect against myopia.

Objective

This study aims to examine the effects of green space around schools on individual myopia risk in high school–aged adolescents and the school-level myopia prevalence.

Methods

Green space was measured using the normalized difference vegetation index (NDVI). A total of 13,380 samples of 51 high schools were selected from a 2021 Beijing Municipal Health Commission survey. Adolescent myopia was defined as a spherical equivalent of ≤–1.00 diopters in the worse eye. Generalized linear mixed models with a binomial error structure were used to analyze the effects of the NDVI on personal myopia risk and adjust them by other factors, such as demographics, exposure time, and outdoor exercise. The effects of the NDVI on school-level myopia prevalence with adjusted demographics and the relative position factors of trees were analyzed through quasibinomial regression.

Results

The overall prevalence of myopia was 80.61% (10,785/13,380, 95% CI 79.93%-81.27%). Although with a 0.1 increase in the 500 and 1000 m buffer NDVIs adjusted by demographic and other factors, the high school–aged personal myopia risk significantly dropped by 16% (odds ratio [OR] 0.84, 95% CI 0.73-0.97) and 12% (OR 0.88, 95% CI 0.79-0.99), respectively. However, only the adjusted 500 m buffer NDVI (by demographics and the position of trees) with a 0.1 increase significantly reduced the school-level myopia prevalence by 15% (OR 0.85, 95% CI 0.74-0.98). Subgroup analysis showed that the adjusted effects of the 500 m buffer NDVI are significant in schoolgirls (OR 0.82, 95% CI 0.72-0.93), juniors (OR 0.82, 95% CI 0.72-0.94), the Han nationality (OR 0.84, 95% CI 0.72-0.97), 1-year exposure (OR 0.84, 95% CI 0.71-0.99) and 3-year exposure (OR 0.78, 95% CI 0.65-0.94).

Conclusions

The greenness of a 500 m buffer around schools is associated with a lower personal myopia risk among adolescents and a lower prevalence of myopia in schools. With regard to prevention and control activities, green space within a 500 m buffer around schools is suggested as an independent protective factor for adolescent myopia.
Implementing Smartphone-Based Telemedicine for Cervical Cancer Screening in Uganda: Qualitative Study of Stakeholders’ Perceptions (Preprint)
Authors: Kabukye Johnblack K , Namugga Jane , Mpamani Collins Jackson , Katumba Andrew , Nakatumba-Nabende Joyce , Nabuuma Hanifa , Musoke Stephen Senkomago , Nankya Esther , Soomre Edna , Nakisige Carolyn , Orem Jackson
Published: January 2023

BACKGROUND

In Uganda, cervical cancer (CaCx) is the commonest cancer, accounting for 35.7% of all cancer cases in women. The rates of human papillomavirus vaccination and CaCx screening remain low. Digital health tools and interventions have the potential to improve different aspects of CaCx screening and control in Uganda.

OBJECTIVE

This study aimed to describe stakeholders’ perceptions of the telemedicine system we developed to improve CaCx screening in Uganda.

METHODS

We developed and implemented a smartphone-based telemedicine system for capturing and sharing cervical images and other clinical data, as well as an artificial intelligence model for automatic analysis of images. We conducted focus group discussions with health workers at the screening clinics (n=27) and women undergoing screening (n=15) to explore their perceptions of the system. The focus group discussions were supplemented with field observations and an evaluation survey of the health workers on system usability and the overall project.

RESULTS

In general, both patients and health workers had positive opinions about the system. Highlighted benefits included better cervical visualization, the ability to obtain a second opinion, improved communication between nurses and patients (to explain screening findings), improved clinical data management, performance monitoring and feedback, and modernization of screening service. However, there were also some negative perceptions. For example, some health workers felt the system is time-consuming, especially when it had just been introduced, while some patients were apprehensive about cervical image capture and sharing. Finally, commonplace challenges in digital health (eg, lack of interoperability and problems with sustainability) and challenges in cancer screening in general (eg, arduous referrals, inadequate monitoring and quality control) also resurfaced.

CONCLUSIONS

This study demonstrates the feasibility and value of digital health tools in CaCx screening in Uganda, particularly with regard to improving patient experience and the quality of screening services. It also provides examples of potential limitations that must be addressed for successful implementation.
The National Coordinated Citrien eHealth Program to Scale Up Telemonitoring: Protocol for a Before-and-After Evaluation Study (Preprint)
Authors: Gijsbers Harm , Nurmohamed Azam , van de Belt Tom H , Schijven Marlies ,   The Citrien 2 Project Leaders and Steering Group
Published: January 2023

BACKGROUND

Sustainable implementation of telemonitoring in health care is challenging, especially if one aims to scale up telemonitoring initiatives nationwide. The National collaborative eHealth program in the Netherlands is supporting the nationwide upscaling of telemonitoring in 3 clinical domains by implementing telemonitoring in all Dutch university medical centers (UMCs). The chosen telemonitoring concepts are (1) telemonitoring solutions in the domain of cardiology, (2) telemonitoring solutions providing care from a distance in obstetrics, and (3) telemonitoring solutions monitoring vital functions in hospital wards.

OBJECTIVE

The aim of this study is to evaluate the upscaling of telemonitoring in Dutch university hospitals in order to gain a better knowledge of the process, methods, and outcomes of nationwide upscaling strategies. Our hypothesis is that by the completion of the Citrien program’s scale-up, telemonitoring will be operational in all UMCs but not normalized in routine care.

METHODS

A before-and-after study will be conducted to assess upscaling. The theoretical frameworks used are the framework for nonadoption, abandonment, scale-up, spread, and sustainability; the Normalization Process Theory; and a project management tool Project Canvas. The primary outcome of the study is the degree of normalization to which health care providers at UMCs consider telemonitoring a part of their routine practice, measured using the Normalization MeAsurement Development tool (NoMAD). Our secondary outcome is the uptake of telemonitoring at the Dutch UMCs, using management data from UMCs’ business intelligence systems query.

RESULTS

Data will be collected between May 2020 and December 2022. Results were retrieved in June 2023. UMCs’ business intelligence systems are queried for data for the secondary outcome measures. There is a risk that the UMCs will not be able to provide this management information. The laws and regulations governing telemonitoring in the Netherlands are changing, with the Electronic Data Exchange in Health Care Act (Wet elektronische gegevensuitwisseling in de zorg) and the European Health Data Space Act expected to positively influence implementation and upscaling.

CONCLUSIONS

The Citrien program is a nationally coordinated change management program that is scaling up telemonitoring across contexts and settings. This study will produce original data on the uptake and upscaling of telemonitoring at Dutch UMCs. Future initiatives to implement eHealth in the health care sector may be guided by the wide range of success factors, obstacles, and experiences collected through this program. The network itself may be of great value impacting future acceleration of eHealth initiatives.

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/45201
A network meta-analysis of immunotherapy-based treatments for advanced nonsquamous non-small cell lung cancer
Authors: Aggarwal Himani , Ndirangu Kerigo , Winfree Katherine B , Muehlenbein Catherine Elizabeth , Zhu Emily , Tongbram Vanita , Thom Howard
Published: January 2023

Introduction:
In the absence of head-to-head trials comparing immunotherapies for advanced nonsquamous non-small-cell lung cancer (NsqNSCLC), a network meta-analysis (NMA) was conducted to compare the relative efficacy of these treatments.
Materials & methods:
A systematic literature review of randomized controlled trials evaluating first-line-to-progression and second-line treatments for advanced NsqNSCLC informed Bayesian NMAs for overall survival (OS) and progression-free survival (PFS) end points.
Results:
Among first-line-to-progression treatments, pembrolizumab + pemetrexed + platinum showed the greatest OS benefit versus other regimens and a PFS benefit versus all but three regimens. Among second-line treatments, an OS benefit was seen for atezolizumab, nivolumab and pembrolizumab versus docetaxel.
Conclusion:
Pembrolizumab + pemetrexed + platinum showed the maximum OS benefit in the first-line setting. In the second-line setting, anti-PD-1/anti-PD-L1 monotherapies were better than docetaxel.
Límites y retos de la globalización: frontera-horizonte y gobierno de la tecnosfera
Authors: Medina García Eusebio
Published: January 2023

En este artículo abordamos el concepto de frontera-horizonte, el cual postula que las fronteras de la globalización deben ser concebidas como retos y límites que afectan a la humanidad como un todo. El objetivo principal es generar un conocimiento teórico y reflexivo que sirva como instrumento de intervención sobre la realidad social para tratar de mejorarla. La metodología utilizada es de carácter cualitativo; combinando las perspectivas emic y etic conforman una perspectiva “glocal”. Nos servimos de información proveniente tanto de fuentes primarias como secundarias, incluyendo la experiencia personal del investigador. Los resultados apuntan a que las causas profundas de la actual situación son de naturaleza intangible y están vinculadas con cuestiones éticas y educativas. De igual manera, entre las principales conclusiones destacamos la necesidad de conformar una nueva conciencia colectiva global —alejada de los postulados del ordoliberalismo— integradora de las diferencias y orientada al bien común.
Mujeres y participación en la política formal: una revisión sistemática de estudios cualitativos
Authors: Francovich Mila , Saletti Cuesta Lorena , Brussino Silvina
Published: January 2023

La presente revisión sistemática de estudios cualitativos tiene por objetivo explorar cómo los estudios de género han analizado las trayectorias políticas de las mujeres. Durante mayo y junio de 2020 se realizaron búsquedas en diez bases de datos bibliográficas. Se seleccionaron 13 estudios y se identificaron tres temas principales y subtemas: 1) socialización política, 2) motivación para involucrarse en la política formal y 3) conciencia de desigualdad por motivos de género con subtemas: a) estereotipos de género presentes en la sociedad y b) prácticas y dinámicas machistas de la política y al interior de los partidos. Este estudio aporta conocimientos acerca de los obstáculos y facilitadores que las mujeres encuentran en el desarrollo de sus carreras políticas. Entre sus limitaciones se halla la heterogeneidad en la calidad de los estudios incluidos. Se concluye que, pese a la diversidad de países y culturas políticas en los que se desarrollaron los estudios, se observa una multiplicidad de comportamientos que obstaculizan la participación de las mujeres en cargos de representación como factor común.
Informalidad y nanoempresas en localidades perimetropolitanas de la Ciudad de México
Authors: Rodríguez Medina Oscar , Alvarado Lagunas Elías , Sánchez Silva Mario
Published: January 2023

El objetivo del presente artículo es estudiar las variables que influyen sobre la preferencia por la formalidad o informalidad de las nanoempresas en la localidad perimetropolitana de Milpa Alta, en la Ciudad de México. Para ello se realizó un experimento controlado a 122 individuos, en el que se destacaron las prerrogativas de la formalidad para obtener una matriz de transición y tres modelos Logit. Los resultados indican que 27% de los empresarios están dispuestos a transitar a la formalidad. Además, en la medida que el monto de la inversión inicial se incrementa, la preferencia por la informalidad disminuye, mientras que la preferencia por la formalidad incrementa cuando la escolaridad del individuo corresponde a licenciatura o ingeniería y, finalmente, entre más baja es la inversión inicial, resulta más difícil la transición informal-formal.
Apropiación docente compleja de las TIC en instituciones educativas dotadas con herramientas tecnológicas
Authors: García-Pinilla José-Ignacio , Rodríguez-Jiménez Olga Rosalba , Olarte-Dussan Fredy Andrés
Published: January 2023

La investigación buscó comprender el proceso de apropiación docente de las tecnologías de la información y la comunicación (TIC) en las escuelas dotadas con herramientas tecnológicas, utilizando el modelo de apropiación de la tecnología (MAT) y la concepción piagetiana de complejidad analítica. Se realizaron grupos focales con los docentes de 82 instituciones públicas de educación secundaria. El corpus resultante se analizó bajo la perspectiva de la teoría fundamentada tomando como base los niveles de adopción, adaptación e integración de las TIC y rastreando diferencias en el proceso debido a la ubicación urbana o rural. Se concluye que los docentes se apropian de las TIC cuando comprueban que es una herramienta útil para su labor con los estudiantes, ya sea como forma de mejorar la comunicación con ellos, como forma de mejorar sus actividades docentes, o bien como forma de motivar a los estudiantes en el mediano o largo plazo.
Las prácticas evaluativas y la concepción de la evaluación del profesorado de francés como lengua extranjera
Authors: Chao Kuok-Wa
Published: January 2023

Esta investigación de tipo cuantitativa realizada con 84 docentes de francés en educación primaria y secundaria de Costa Rica tiene como objetivo describir sus prácticas evaluativas usadas en las clases de francés como lengua extranjera. Se propone específicamente identificar las concepciones de la evaluación del personal docente de francés y documentar los métodos y los instrumentos de evaluación empleados por este grupo de docentes. Para la recolección de datos se utilizó un cuestionario aplicado en línea. Como resultados principales, el personal docente tiene una concepción tradicional de la evaluación; la instrumentación utilizada para evaluar a sus estudiantes es el examen, el trabajo cotidiano o las tareas. El cuerpo docente se basa en los objetivos y en los contenidos de los cursos para realizar las evaluaciones y utiliza sobre todo una retroalimentación oral colectiva. Para este grupo de docentes la evaluación es una práctica que se realiza individualmente.
Educación inclusiva y nueva gestión pública en las políticas de liderazgo escolar en Chile
Authors: Valdés René , Campos Fabián , Fardella Carla
Published: January 2023

Este artículo reporta los resultados de un estudio que analiza las políticas educativas que interpelan y regulan la labor de los equipos directivos desde una perspectiva inclusiva y a la luz de los principios de la nueva gestión pública (NGP) en Chile. Se realizó una revisión documental y un análisis temático de 24 textos oficiales publicados entre los años 1980 y 2020. Los resultados muestran que, en las políticas de liderazgo, coexisten cuatro versiones sobre la educación inclusiva que interpelan la labor de los equipos directivos: como programa de apoyo, como ambiente escolar, como conocimiento profesional y como asunto legal. Estos modos de interpelación conviven, a la vez, con otros que son propios de la NGP, como la promoción de un estilo de gestión basado en indicadores, en resultados y en la competencia. Las discusiones finales sugieren una contraposición de racionalidades que afectan las posibilidades de liderar escuelas inclusivas.
Characterization of temporomandibular joint articular disc progenitor cell clones
Authors:   Department of Orthopaedics and Rehabilitation, Oregon Health & Science University, Portland, OR, USA, Weekes KJ , Lam P , Kim C , Johnstone B
Published: January 2023

A critical component of the temporomandibular joint (TMJ) is the fibrocartilage articular disc (AD). Researchers have attempted to regenerate the AD to alleviate TMJ osteoarthritis but alternative cell sources for use in AD regenerative approaches are needed due to insufficient extracellular matrix (ECM) production by total articular disc cells (TACs). Tissue-specific progenitor cells have been identified in many tissues. The aim of the present study was to identify adult multipotent progenitor cells within the AD suitable for regenerative medicine applications. A novel AD progenitor cell population was identified in rhesus macaques. Clonally derived articular disc progenitor cells (ADPs) were isolated using fibronectin differential cell adhesion. ADPs represent between 1 and 3 % of the TAC population and are capable of in vitro expansion beyond 60 population doublings. ADPs were characterized using osteogenic, adipogenic, and fibrochondrogenesis differentiation assays. Clones exhibited phenotypic plasticity, differentiating into osteocytes, adipocytes, and fibrochondrocytes. ECM secretion profiles following fibrochondrogenic differentiation were assessed using immunohistochemistry (IHC), fluorescently activated cell sorting (FACS), total collagen, and glycosaminoglycan (GAG) assays and compared with TACs, articular cartilage progenitor cells (ACPs), tendon progenitor cells (TPCs) and bone-marrow-derived mesenchymal stem cells (BMMSCs). ADP pellet cultures produced a biochemical phenotype similar to native AD tissue, with production of versican (VCAN) and collagen types I, II, III, and VI (COL1, COL2, COL3, COL6). However, clonally derived ADP cell lines produced different amounts of ECM and exhibited different expansion potentials. These findings indicated flexibility in clone selection for potential regenerative strategies to recapitulate native anisotropy.
Hand Gesture Recognition
Authors: Kotavenuka Swetha , Kodakandla Harshitha , Krishna Nimmakayala Sai , Rao Dr. S P V Subba
Published: January 2023

Abstract: This work presents a computer-vision-based application for recognizing hand gestures. A live video feed is captured by a camera, and a still image is extracted from that feed with the aid of an interface. At least once per count hand gesture (one, two, three, four, and five), the system is trained. After that, the system is given a test gesture to see if it can identify it. Several algorithms that are capable of distinguishing a hand gesture were studied. It was determined that the highest rate of accuracy was achieved by using the computational neural network known as the Alexnet algorithm. Traditionally, systems have used data gloves or markers as a means of input. We are free to use the system however we like. In this way, the user can make natural hand gestures in front of the camera. The system implemented serves as an extendable basis for future work toward a fully robust hand gesture recognition system, which is still the subject of intensive research and development.
Granulation
Authors: Sirame Prathmesh , Khairnar Rajeshwari , Tasgaonkar Rupali
Published: January 2023

bstract: Granulation is one of the most important unit operations in the production of pharmaceutical oral dosage form. It is the process in which primary powder particles are made to adhere to form larger multiparticle entities called granules. the Granulation process will improve flow and compression characteristics, reduce segregation, improve content uniformity, improve density and eliminate excessive amounts of particles. Improved yields, decreased tablet defects, higher productivity, and decreased downtime will be the outcomes. All across the world, pharmaceutical products are processed utilising the direct compression, wet granulation, or dry granulation techniques. The process is determined by the properties and capacity of each element to appropriately compress, expel, and disintegrate. The review article provides the most recent technological breakthroughs. This review provides an overview of them along with a brief explanation of each development’s importance and limits. Each drug material provides a different problem during formulation creation, which the scientists working on the process must take into account at the process selection stage.
Mapping of Farmer Economic Institutions for the Development of Food Crop Farmers Corporations in East Java
Authors: Gunawan  , Ardiansyah  , Tafakresnanto C , Latifah Evy
Published: January 2023

To increase the reinforcement of farmer capacity, farmer institutions and business capacity become the primary capital for forming farmer corporations. Hence, it is necessary to develop a mapping of agricultural areas based on farmer corporations, especially food commodities in East Java. It combines a series of programs, especially farmer corporations, into one unified whole to align with the Strategic Planning for Regional Development.  Mapping of farmer economic institutions (KEP) or farmer group classes to find out which farmer group classes have the potential to become farmer economic institutions. Middle and primary-class farmer groups are a class having the potential to be developed and included as a category of farmer economic institutions (KEP). Accordingly, agricultural areas, which are rice, maize, and soybean areas, can be delineated, having the potential to be developed as a farmer economic institution as a form of farmer corporation in the region. From the research results, it is obtained that farmer economic institutions (KEP) exist in several regencies in East Java. The highest economic institutions were formed in the regency of Tulungagung and Bojonegoro. Some regencies only have one institution that can be formed. The number of formed farmer economic institutions (KEP) can create farmer corporations which are essential for the growth and development of farmer corporations as a basis for improving farmer welfare.
Effectiveness of Agricultural Extension Communication of Spinach Farming
Authors: Pasaribu Asriel Sumurung , Novanda Ridha Rizki
Published: January 2023

This study aimed to analyze Agricultural Extension Communications' effectiveness in Spinach Farming in Kasturi Farmer Groups in Pulo Jantan Village, Na IX-X District. This study was conducted on a Kasturi farmer group in Pulo Jantan Village, NA IX-X District, Labuhanbatu Utara Regency. The research location was determined intentionally (purposively), considering that the farmer group was classified as active in extension activities. The method used to collect data is using interview techniques using prepared questionnaires. Data analysis was performed using descriptive analysis to get a clearer picture and detail about a situation based on the information obtained, collected, classified, and interpreted to get the information necessary to analyze the existing problems. The result is that communication of agricultural extension workers in spinach farming in the Kasturi farmer group in Pulo Jantan Village, Na IX-X District, is categorized as effective. This is seen from the percentage of 3 aspects, namely cognitive, affective and conative, in the effective category. The most practical aspect of counseling communication is the cognitive aspect, with the highest percentage of effective categories. It is better if agricultural extension workers can adapt the material presented according to the problems farmers face.
Dynamic properties of a motor grader seat with quasi-zero static characteristics
Authors:   Siberian State Automobile and Highway University, Korytov M.S. , Sherbakov V.S. ,   Siberian State Automobile and Highway University, Kashapova I.E. ,   Siberian State Automobile and Highway University
Published: January 2023

During operation, transport and technological machines and equipment experience significant vibration effects from the working environment, which are transmitted to the human operator through the cab seat. The negative impact of dynamic influences and vibrations transmitted through the seat to the operator is noted in many works. The use of vibration protection systems for operator seats requires their simulation and study on mathematical models, which is an urgent task in the design of such systems. Vibration protection systems with the effect of quasi-zero stiffness are promising. To study vibration protection systems with quasi-zero stiffness, a complex simulation mathematical model of a motor grader was developed, the movements of which are of a spatial nature. The model includes subsystems of supporting elements of the base chassis, vibration-proof supports of the operator’s cabin, and, finally, the vibration-proof mechanism of the operator’s seat. The last subsystem makes it possible to study vibration protection mechanisms with a given size of the zone of quasi-zero stiffness in the static force characteristic. Using the developed complex simulation model, the system’s responses to step actions exerted on the elements of the running equipment of the base chassis of the motor grader were studied. The effects on one of the wheels of the front balance axle and one of the wheels of the rear balance bogie of the motor grader were investigated. Two static power characteristics of the vibration-protective seat system were considered, one of which had a section of quasi-zero stiffness, and the second did not. According to the results of the computational experiment, it was established that the vibration protection system with a quasi-zero stiffness section provides maximum seat accelerations that are ten times less than a vibration protection system without a quasi-zero stiffness section. This confirms the promise of using vibration protection systems with the effect of quasi-zero stiffness.
Life and work strategies of pensioners in contemporary Russia
Authors: Barkov S. A. , Markeeva A. V. , Kolodeznikova I. V.
Published: January 2023

Based on the data of the All-Russian survey of pensioners (February 2022), the article reveals their opinions on working in retirement, reasons for continuing work, problems when changing jobs, attitudes to new forms of employment, and life priorities. The article continues the analysis presented in the article “Employment of the elderly: Social imperatives and barriers in contemporary Russia” (2022; 22 (1)). The most important factor affecting the life strategies of the elderly in the post-industrial society is their increasing involvement in labor activity. The survey showed that the basic incentive for working in the older age is additional income. In depressed regions and during crises, work is one of the possible means for survival of both pensioners and their families. However, under the growing well-being of working pensioners, social motives and incentives for self-realization become fundamentally important. Differences in the pensioners’ motivation to continue their labor activity are determined by both personal characteristics (gender, age) and local social-economic circumstances (place of residence). Thus, Moscow pensioners, who get city allowances and feel less poor than pensioners in other regions, express special opinions on a number of issues. Life strategies differ significantly by gender: retired women are less satisfied with their status as non-working pensioners and are more willing to use new forms of employment, which may lead to more active employment of women in the future. More than a third of pensioners, contrary to stereotypes, are ready to work remotely. Most pensioners are not ready to become selfemployed, but many start to consider this form of employment and admit its benefits. To improve their social role, pensioners propose to develop volunteer and educational projects in which they could share knowledge and experience with the younger generations, and to hold events that would show the elderly’s contribution to the development of society.
The сore of the Russian power reputation space: Expert assessment and public opinion
Authors: Rozanova N. N. , Sukhova E. E.
Published: January 2023

The article is based on the data collected in the study of the Russian power reputation space. The study focused on both the Russian power in general (official state and municipal power) and the regional power including the state executive power of the region. The authors defined several levels (federal/regional/municipal) and branches (legislative/executive/judicial) of power as the coordinate system structuring the space of power; and for the regional executive power, also peculiarities of responsibilities carried by the subjects of power. The study aimed at identifying the core and periphery of the reputation space of the Russian power based on the results of the two-stage sociological study - expert assessments and mass survey. The authors argue that the reputation space of both the Russian power in general and the regional power is multi-component and formed by the reputation of different subjects of power with a high degree of mutual influence. The study revealed a significant difference in the definitions of the core of the reputation space by the population and experts. The federal power constitutes the core of the reputation space of the Russian power as structured by its levels, according to experts and public opinion. Experts believe that the executive branch constitutes the core of the reputation space as structured by its branches, while the influence of the reputation of different branches seems balanced for public opinion. The similar situation was identified in the reputation space of the regional power. The authors also identified the significant influence of the personification factor on the reputation space of both the Russian power in general and the regional authorities. This leads to a ‘shift’ of the reputational core, which becomes especially evident in public opinion on the role of the president’s reputation: every third respondent identifies it with the reputation of the entire Russian power.
Wealth concentration and the ‘patrimonial middle class’ in the contemporary European-American civilization
Authors: Čižo E. , Menshikov V. , Kokarevica A. , Selivanova-Fyodorova N.
Published: January 2023

The study aims at the comparative analysis of the trends in wealth concentration and formation of the ‘patrimonial middle class’ (the term by Piketty) in the countries of the contemporary European-American civilization (EAC). T. Piketty suggests that wealth concentration is increasing again (as in the 18th - 19th centuries), and the formation of the ‘patrimonial middle class’ is the most significant structural change in the long-term wealth distribution. The authors chose five parts of the EAC from West to East: USA, Western Europe, Latvia, Ukraine, and Russia. To measure and compare wealth inequality, the authors used statistical deciles: the top 10 % (including the top 1 %), the middle 40 % and the bottom 50 % of the population. 1995 and 2021 were chosen as time points for the diachronic analysis of the data from the World Inequality Database. The study results show that in different parts of the contemporary EAC, wealth concentration and the formation of the ‘patrimonial middle class’ differ in pace and sometimes in direction: from rapid concentration to deconcentration. Wealth concentration in the hands of the top 1 % of Americans has increased over the past 26 years from 28 % to 35 %, of Russians - from 21 % to 48 %. According to Piketty, such a situation (especially as in Russia) is a harbinger of social revolution. In terms of the wealth concentration level, Latvia and Ukraine represent an intermediate case between Western Europe and the USA/Russia. At the same time, the USA, Western Europe and Russia differ greatly in the cultural-value perspective. The authors question the united EAC in the 21st century and define it as split into an ‘initial core’ (European civilization) and two constantly conflicting ‘peripheries’ (American and Russian civilizations).
The dynamics of capitalism and the return of classes
Authors: Anisimov R. I.
Published: January 2023

The growing social inequality and the abandonment of the welfare-state model raise the question of the return of classes to the historical arena. The author argues that the contemporary society can be characterized as capitalist due to its main structural element - a pattern of striving for profit; at the same time, the contemporary capitalist society has changed the vector of making profit from external expansion (search for new markets and centers of production) to internal intensity (automatization, increased exploitation, total commodification, removal of institutional barriers to profit). Today, capitalism has exhausted the possibilities of external expansion and is changing its strategy to the restructuring of social systems and its actors, which is accompanied by the abandonment of the welfare-state model and by the growing instability in labor relations. This leads to the situation in which middle classes disappear and social inequality grows. The concept of classes developed by K. Marx has regained its importance, since the theories created in the middle of the 20th century no longer correspond to the contemporary realities. The article revises the Marxist class model, in particular the author argues that the type of ownership is no longer a key differentiating criterion, and capitalists and proletarians are no longer the main classes of the contemporary society. The classes of employers and precariat are more relevant for describing the contemporary society. The ideas of these two classes also differ: the precariat strives to preserve social guarantees and labor rights; while employers, on the contrary, strive to maximize profits by reducing social guarantees and violating labor rights.