bluuebunny/crossref_metadata_2025 huggingface dataset:
Perceived Authenticity and Place Attachment among Mountain Tourists: A Case Study Exploration in the Gaoligong Mountain in Southwest China
Authors: Zhao Yuanyuan , Liu Hongfang , Yin Zhaoyin , Zou Jianqin
Published: January 2025

In the context of the embodiment and humanistic turn in tourism research, exploring new pathways for mountain tourism development from the perspective of the relationship between tourists' perceived authenticity (PAY) and place attachment (PAT) is of great significance. This approach aims to strengthen the emotional connection between mountain tourism and target tourist groups, improving the quality of the mountain tourism experience. This study defines the relationship between PAY and PAT among mountain tourists, clarifies their measurement dimensions, and constructs a research model for PAY and PAT in mountain tourism. Taking Gaoligong Mountain as a case study site, it collected 297 valid responses through a questionnaire survey. Seven research hypotheses were tested by the using structural equation modeling (SEM). The results show that: (1) The results of the reliability and validity revealed that the division of PAY are objective authenticity (OA) and existential authenticity (EA), and PAT are place dependence (PD) and place identity (PI), corresponding to the particular scenario of mountain tourists; (2) OA significantly enhances both PD and PI, and PD positively influences PI; (3) Analyses of Mediating Effects reveal that neither OA nor EA affects PI through PD; (4) EA significantly affected PI but not PD. The research results reveal the underlying mechanisms and dynamics between the dimensions of PAY and PAT among mountain tourists. Therefore, this study suggests that local governments and business enterprises should strengthen the emotional connection between mountain tourism and tourists by focusing on five key areas: enhancing PAY, aiming at target segments, promoting PI, understanding tourist needs, and improving policies and planning. These efforts will contribute to the sustainable and high-quality development of mountain tourism.
Intra-Household Portfolio Decision in Retirement: Bargaining Power and Gender Health Differences
Authors: Du You
Published: January 2025

This paper investigates how the health-determined bargaining power affects the joint portfolio decision-making of retired households. Data demonstrate a decline in the risky share of married households after retirement, whereas the risky share of single households remains relatively stable. Meantime, wives tend to be younger, healthier, and more risk-averse than husbands. This suggests a potential correlation between health-determined bargaining power dynamics and the household’s portfolio allocation in retirement: as people age, health factors play a more crucial role in determining bargaining power. Consequently, the wife’s bargaining power strengthens, leading the household’s collective portfolio decisions to increasingly reflect her preferences. This dynamic underscores the importance of considering health factors in understanding how joint portfolio decisions are made in retirement. It highlights the potential role of intrahousehold bargaining power in shaping financial outcomes. Realizing this knowledge, policymakers can enhance their ability to better support households’ financial planning and choices during retirement.
Impact of Auditors’ Industry Specialization and Longevity on Professional Skepticism
Authors: Sollfrey Robert , Mekonnen Medhanie , Chien Wen-Wen , Mayer Roger
Published: January 2025

As a result of financial scandals, such as GE Co. and AIG, professional skepticism received increased significance in the field of auditing. Grounded in Hurtt’ s professional skepticism framework, this quantitative correlational study aimed to examine the relationship between years of auditor experience, the extent of industry specialization of the auditor, and the variation in the level of professional skepticism. The study included data from 68 U.S. accountants and auditors. The results of the multiple regression model showed that at F(2, 65) = 4.414, p = 0.016, R2 = 0.12, auditor’s industry specialization was a significant factor, which is positively associated with professional skepticism. Auditor’s industry specialization was statistically significant (ß= .316, t = 2.704, p = .009), accounting for a higher contribution to the model. Auditor’s longevity in the field was not statistically significant, thus, did not explain any significant variance in the performance of professional skepticism. The results of this study extended research on professional skepticism attributes and expanded our understanding of predictive variables.
Disease Severity and CT Score as Predictors of COVID-19 Outcomes: A Single-Center Study
Authors: Terkeš Vedrana , Toli Anela , Bištirli Marin , Marketin Tina , Morovi Miro
Published: January 2025

Objectives: to find a must common anchor point(s) in daily clinical work with COVID-19 patients, which could suggests to us the possible outcome.

Materials and Methods: The study population consisted of 956 patients diagnosed and hospitalized with COVID-19 between March 2020 and March 2023 at Zadar General Hospital, Croatia. Data collection was both, prospective and retrospective. All the patients were grouped according to the National Institutes of Health (NIH) guidelines disease severity criteria. Computed tomography (CT) was performed mostly in the severe and critically ill patients and in a number of moderately ill patients with signs of disease progression. The CT score was calculated based on the extent of lobar involvement. The two primary objectives of our investigation of disease outcome were death and oxygen-dependence/independence in survivors at discharge from hospital.

Results: The mortality rate was 31.8% (304/956); oxygen-dependence were recorded in 109 (11.4%) of patients at discharge from hospital. Our results showed that there was a statistically significant correlation between the variables of age and comorbidities and death outcome. The results of the binary regression analysis of disease severity in predicting the disease outcomes, death/survival, and oxygen-dependence at discharge showed that the severity of clinical condition was a statistically significant predictor of both disease outcomes.

The one-way analysis of variance (ANOVA) to predict the influence of the CT score values on the disease outcomes showed that there was no statistical significant difference in CT score values between the deceased patients and those who survived. However, the ANOVA analysis of variance to predict the influence of the CT score values on oxygen-dependence or independence at discharge showed a statistical significant difference (F(1,643) =32.37, p<0.05) in the CT scores between the patients who were oxygen-dependent (M=9.75, Sd=9.65) and those who were oxygen-independent (M=4.96, Sd=7.68) at discharge.

Conclusion: Our results showed that the categorization of patients according to their disease severity and CT score could be good anchor points in daily clinical works with COVID-19 patients, which could suggests to us the possible outcome to have been expected in moderate, and particularly in severe/critical patients at their admission to hospital.
Occurrence and Frequency of Gene Mutations Associated with Rifampicin (RIF) and Isoniazid (INH) Resistance from Multidrug Resistant Mycobacterium Tuberculosis (MDRTB) in Lagos, Nigeria
Authors: TY Raheem , BA Iwalokun , MA Fowora , KA Osuolale , AA Adesesan
Published: January 2025

Background: Despite the tremendous improvements in the diagnosis and treatment of tuberculosis, pulmonary tuberculosis (PTB) remains a leading cause of morbidity and mortality in adults and children worldwide. The World Health Organization (WHO) recommends detection of MDR TB using bacteriological confirmation of TB and testing for drug resistance using rapid molecular tests, culture methods or sequencing technologies. M. tuberculosis strains resistant to multiple anti-TB drugs are becoming increasingly common. Different independent mutations of rpoB, katG and InhA genes encoding either the drug target or the enzymes involved in drug activation have been found to be one of the strategies responsible for resistance to Rifampicin and Isoniazid.

Methods: This cross-sectional, multicentre study was conducted on MDRTB isolates collected from pulmonary TB patients in Lagos, Nigeria from May 2012 to October 2016. After informed consent, structured questionnaires were administered to obtain sociodemographic data. Sputum samples were collected and processed for microscopy and culture using Lowenstein-Jensen medium. Isolates were identified by biochemical and molecular methods and drug susceptibility testing was performed using MIC, proportion and line probe Assay methods.

Objectives: The study investigated the occurrence and frequency of gene mutations associated with rifampicin (RIF) and isoniazid (INH) resistance from the isolated MDRTB and assessed whether all the M. tuberculosis which elicited MDRTB phenotype had mutation markers.

Results: Of the 48 M. tuberculosis that elicited MDR phenotype by the proportion and MIC methods, 2 (4.2%) isolates lacked any of the inhA, katG and rpoBgene mutations associated with RIF and isoniazid resistance in the line probe assay method. The highest occurring rpoB mutation conferring RIF resistance among the MDR M. tuberculosis tested was 97.3% with mutation point S531L at a frequency of 60.4% followed by H526D mutation (22.9%), H536Y (8.3%) and D516V (6.3%). The S315T mutation of the katG gene was responsible for 50% of isoniazid resistance among the MDR isolates. This was followed by C-15T mutation (14.6%), S94A mutation (12.5%) and 1194A (8.3%) of inhA mutation points.

Conclusions: Different mutations of genes encoding either drug target or the enzymes involved in drug activation such as S531L, H526D, H536Y, D516V, S315T, C-15T and S94A were detected in MDRTB isolates. The study also showed that lack of inhA, katG and rpoB resistance defining mutations may not be sufficient as markers of susceptibility to anti-TB drugs. There is need for a nation-wide study of the pattern of mutations of drug/enzyme gene targets in MDRTB in Nigeria.
Prevalence of HBV (Hepatitis B Virus) Serological Markers in Patients admitted to the Bacteriology and Virology Laboratory of the University Hospital of FANN DAKAR, SENEGAL
Authors: Madiagne Der , Ahmet Niang Aissatou , Amadou Diop , Fatoumata Diallo , Habib Sarr , Baidy Dieye , Rougyatou Kâ , Lamine Dia Mouhamadou
Published: January 2025

Objective: Hepatitis B is a liver infection that is widespread throughout the world and constitutes a real public health problem, with 2 billion people infected by the virus worldwide. The aim was to study the prevalence of Hepatitis B virus (HBV) markers in patients received at the Bacteriology-Virology laboratory of CHNU of FANN.

Methodology: This is a retrospective study based on the exploitation of results covering the period from January to November 2020. The markers included in our study were: HBs antigen (HBsAg); anti HBs antibody (anti HBsAb); HBe antigen (HBeAg); anti HBe antibody (anti HBeAb); anti HBc antibody (anti HBcAb). The data were collected from registers, then entered and processed using EPI-INFO software version 3.5.4.

Results: 1,590 patients were seen during the study period for serological markers of hepatitis B virus. The mean age was 41.90 years, with extremes of 2 years and 100 years. Women accounted for 55.98%, giving a sex ratio (M/F) of 1.27. The age group [20-40 years] was the most representative of our study population with a percentage of 47.9%, followed by the age group 40-60 years with a percentage of 23.9%. The prevalence of HBsAg-positive patients was 11.1%, HBeAg-positive patients 9.15%, HBeAb-positive patients 66.1% and HBcAb-positive patients 68.5%; 59.92% of patients had an anti-HBs antibody titre above the protective threshold (greater than 10 IU/L). Seroprevalence was higher in women than in men, with 49.37% in men and 50.63% in women, i.e. a total of 79 men for 81 women.
The Role of Health Coaches in Helping Patients Make Health-Related Decisions and Modify Their Behavior: Experiences from a Clinical Trial
Authors: Mousa Ola , Alharsan Mai Salem , Alsultan Dalal Abdulrahman , Barnawi Aysha Ahmad , Aljanabi Hameeda Matooq
Published: January 2025

Background: The objective of health and wellness coaching is to provide patients with active participation in their self-management built on their personal goals and willingness to change through a patient-centered intervention. By changing health behavior, health coaching helps users improve their self-care.

Aim: The purpose of this study is to examine how coaches support participants and to understand the elements that contribute to engagement and success.

Methods: A qualitative-descriptive design was used to gather insights from health coaches participating in semistructured interviews. As a convenience sample, participants in a health coaching program in Al Khobar, Saudi Arabia were recruited. Five health coaches participated in the study, giving a clear picture of their experiences. Those who work at Al Khobar primary health care centers or have recently started working there. Data was collected between September 15 and November 15, 2023.

Results: Among the study participants, two were diploma nurses, two had a bachelor's degree, and one had a master's degree. They are all female nurses. The majority of health coach stated that they had worked with their patients for 2 years or more. Based on our analysis, we identified five themes: Availability, Trusting relationship, Personal support, Decision support, and Bridging.

Conclusion: It has been found that availability and continuity of communication with patients are key characteristics of a successful coaching relationship, as is a strong relationship based on mutual trust and respect for patient confidentiality. Furthermore, coaches support patients' decision-making and bridge the gap between them and their clinicians by providing personalized and supportive care.
PENGARUH SALES GROWTH, PROFITABILITAS, DAN UKURAN PERUSAHAAN TERHADAP STRUKTUR MODAL
Authors: Dewi Irma , Mirdawati Mirdawati
Published: January 2025

Penelitian ini memiliki tujuan yaitu menganalisis perubahan dalam struktur modal perusahaan padasubsektor F&B (Food and Beverage) yang tercatat di Bursa Efek Indonesia (BEI) berdasarkanpertumbuhan penjualan atau sales growth, profitabilitas, serta ukuran perusahaan selama periode 2016-2020. Dalam penelitian kuantitatif ini, digunakan teknik purposive sampling sebagai metode pengambilansampel menggunakan jenis data sekunder yang merupakan data yang telah dikumpulkan sebelumnya.Sampel sebanyak 13 perusahaan mewakili populasi perusahaan pada subsektor industri F&B (Food andBeverage) yang tercatat di BEI selama periode 2016-2020. Dalam penelitian ini melakukan beberapa uji,seperti uji asumsi klasik, regresi linier berganda, pengujian hipotesis, serta menganalisis statistikdeskriptif menggunakan perangkat lunak SPSS versi 25.. Hasil dari beberapa uji yang telah dilakukanadalah sales growth, profitabilitas, dan ukuran perusahaan semuanya dipengaruhi oleh struktur modalsecara parsial.
Aprendizaje autorregulado en entornos virtuales y logro de competencias del inglés en estudiantes de secundaria
Authors: Mamani Hilasaca Magna Tecla
Published: January 2025

La pandemia de COVID-19 transformó la educación, impulsando la adaptación de estudiantes y docentes a plataformas digitales para conllevar el proceso de enseñanza-aprendizaje a distancia. Este estudio se propuso analizar la relación entre el aprendizaje autorregulado en entornos virtuales y el logro de competencias en inglés en estudiantes de segundo grado de secundaria de la Institución Educativa Emblemática “Tawantinsuyo” en Desaguadero, Puno–Perú. Con un enfoque cuantitativo y un diseño no experimental de tipo descriptivo-correlacional, se incluyó una muestra de 115 estudiantes de entre 13 y 14 años. Para la recolección de datos, se aplicaron la Escala de Aprendizaje Autorregulado en Contextos Virtuales y el Acta de Notas del año académico 2021. Los datos fueron procesados mediante análisis descriptivo, Chi-cuadrado y el coeficiente de correlación Rho de Spearman. Los resultados evidencian que el 54.8% de los estudiantes muestra un nivel moderado de aprendizaje autorregulado y el 60% logra el nivel de competencia esperado en inglés. Aunque la correlación de Spearman mostró una correlación positiva débil y significativa, especialmente en escritura (r = 0.231, p = 0.013), el análisis de chi-cuadrado no mostró una asociación estadísticamente significativa. En conclusión, si bien los estudiantes con un mejor aprendizaje autorregulado en entornos virtuales tienden a tener un mejor desempeño en inglés, otros factores podrían estar asociados a su logro académico.
Reporte de sostenibilidad de universidades: Una revisión bibliométrica y literaria de la base de SCOPUS
Authors: Hernández-Pajares Julio , Venegas Morales Cecilia , Tolentino-Monjorte Hilda
Published: January 2025

Las universidades contribuyen e informan sobre sus contribuciones al desarrollo sostenible; sin embargo, estas acciones evidencian la ausencia de estrategias, gestión, y control de sus objetivos, lo que destaca la necesidad de políticas de gobernanza más robustas y la implementación de estándares internacionales. El objetivo de esta investigación es realizar una revisión bibliométrica y de literatura para analizar el origen, contenido y contribuciones de las publicaciones sobre reportes de sostenibilidad en universidades disponibles en la base de datos SCOPUS, contribuyendo al desarrollo teórico de este campo. El estudio aplicó un enfoque cuantitativo descriptivo para examinar la evolución y procedencia de los artículos, complementado con un análisis cualitativo de contenido de palabras clave, enfoques teóricos y aportaciones académicas. Los resultados evidencian un crecimiento no sostenido de las publicaciones, principalmente de autores de universidades europeas. Predominan los estudios cuantitativos y descriptivos, enfocados en el análisis de reportes elaborados según los estándares de la Global Reporting Initiative (GRI) y fundamentados principalmente en la teoría de los stakeholders. Se concluye que existe una brecha significativa en la investigación sobre la sostenibilidad en universidades, particularmente en países en desarrollo. Finalmente, se proponen recomendaciones para fortalecer las contribuciones de las universidades hacia el desarrollo sostenible.
Religious Tolerance Model in Salatiga: Analysis of the Implementation of Religious Moderation Concept in a Multicultural City
Authors: Nugroho Muhammad Aji
Published: January 2025

This study examines the model of religious tolerance in Salatiga, a city known for its religious diversity, focusing on the role of Islam in promoting religious moderation. Salatiga has been recognized as one of Indonesia's most tolerant cities due to strong religious awareness, supportive government policies, and the active role of religious leaders in fostering interfaith harmony. The concept of religious moderation in Salatiga emphasizes not only passive acceptance of differences but also active efforts to create peace and mutual support. However, challenges such as social tensions and identity politics still persist. This research, using a qualitative approach with case study methodology, explores the implementation of religious tolerance in Salatiga through in-depth interviews, documents, and participatory observations. The findings highlight key strategies for maintaining tolerance, including the involvement of religious leaders, optimizing local wisdom, implementing social justice-based government regulations, promoting inclusive religious understanding, and integrating tolerance into local traditions. The study concludes that while Salatiga serves as a strong example of religious tolerance, continuous efforts are needed to foster peace and strengthen social cohesion in a pluralistic society.
Politeness Pragmatic Orientation in the Production of Advice-giving Speech Acts in Arab TV Talent Shows
Authors: Alabdali Tahani
Published: January 2025

Identifying and understanding the distinctive features of speech acts’ realization across different cultures is essential for the pragmatic profiling of any language variety. Existing literature on advice-giving speech acts in Arabic predominantly examines religious texts composed in classical Arabic, overlooking everyday utterances spoken in contemporary Arabic dialects. Although Arabic has many varieties across different cultures, there are some shared values and beliefs that connect various Arab speech communities. Consequently, certain generalizations regarding acceptable politeness patterns in the Arab culture may be established, while acknowledging the presence of cultural and linguistic peculiarities. This study offers a descriptive analysis of spontaneous speech, emphasizing the politeness patterns delineated by Leech (2014), in the context of advice-giving in the Arab culture. The data of this study was obtained from ‘Boulevard Almawaheb’ talent show, comprising a total of seventy-nine advice-giving acts. The analysis followed the mixed-method design, mainly applying qualitative content analysis, supported by quantitative data. The findings indicate a preference for on-record indirect strategies over direct strategies and hints, along with a tendency to prioritize certain constraints, such as Approbation. The present study seeks to address the research gap in advice-giving pragmatic orientation within the Arab culture, with the intention of contributing to the establishment of a comprehensive pragmatic profile of speech acts in the Arab world.
VARIOUS NON-SURGICAL THERAPY IN CARPAL TUNNEL SYNDROME THAT CAN BE AN OPTIONAL THERAPY FOR DENTISTS: SCOPING REVIEW
Authors: Brigitta Brigitta , Anggraini Wita , Sulistyowati Indrani , Ariyani Annisaa Putri , Holil Levana
Published: January 2025

Introduction: Carpal tunnel syndrome (CTS) is a common condition among dentists due to awkward hand positions, repetitive hand movements, mechanical pressure on the palms, strong grips, and vibration of tools involved in their work. Non-surgical therapy is recommended for mild to moderate levels of CTS, while surgical treatment may be considered for severe cases. Aim: This study aims to determine the effectiveness of various non-surgical therapy for CTS. Method: The literature search used Boolean language in PCC format on PubMed and Google Scholar databases. The literature search was according to PRISMA-ScR flow chart guidelines and 6,641 articles were obtained. 16 articles met the inclusion criteria, consisting of: splinting (n=2), local steroid injection (n=2), median nerve neuromobilisation (n=2), and journals that tested and compared a combination of non-surgical therapies or more than one non-surgical therapy (n=10). Result: This review shows that non-surgical therapies are effective for CTS patients. Conclusion: Various non-surgical treatment for CTS is effective in reducing pain and improving hand functional ability. These therapies can be an optional therapy for dentists with high CTS risk factors.
Efektivitas Daun Pandan (Pandanus amaryllifolius) , Daun Sereh (Cymbopogon ciratus), Dan Cengkeh (Syzygium aromaticum) Sebagai Penolak Lalat
Authors: Novarianti
Published: January 2025

Latar Belakang : Salah satu agen utama dalam penyebaran sejumlah penyakit menular mekanis, termasuk kolera, tipus, kolera, disentri, dan penyakit saluran pencernaan lainnya, adalah lalat. Mengontrol vektor lalat diperlukan karena ini. Memanfaatkan zat aktif yang diperoleh dari tumbuhan atau dari tanaman yang dapat berperan sebagai modal utama untuk mengendalikan vektor, seperti cengkeh, pandan, dan daun serai. Tujuan : Tujuan penelitian mengetahui efektivitas Daun Pandan, Daun Sereh dan Cengkeh dalam menolak Lalat. Metode : Jenis penelitian yang digunakan adalah eksperimen. Dengan Desain penelitian Posttest Only With Control Design. Total Lalat uji yang digunakan yaitu sebanyak 400 ekor dengan 3 perlakuan dan 5 kali pengulangan, teknk pengambilan data primer diperoleh dari hasil uji yang dilakukan sedangkan data sekunder doperoleh dari berbagai sumber referensi yang terkait. Penelitian ini dilaksanakan pada bulan oktober serta analisa data dilakukan dengan Annlisa of Variance (Uji ANNOVA) untuk membandingkan Efektivitas lalat berdasarkan bahan daun pandan, daun sereh, dan cengkeh. Hasil : pada dosis 9 gram daya tolak daun pandan sebanyak 34%, daun sereh sebanyak 74%, cengkeh sebanyak 58%. hasil test of homogeneity of variances di dapatkan hasil nilai sig 0,052 yang artinya lebih besar dari 0,05 maka dapat diartikan  bahwa hipotesis 0 (Hₒ ) di tolak yang dapat diartikan sebagai uji coba pada daun pandan,daun sereh,dan cengkeh adalah sama (homogeny). Kesimpulan : bahwa yang efektif dalam menolak lalat yaitu daun sereh. Saran untuk masyarakat jika ingin menggunakan bahan daun pandan dan cengkeh sebagai penolak lalat sebaiknya jumlah dosis yang digunakan ditambahkan lagi agar bahan tersebut mampu menolak lalat.
scRNA-seq reveals elevated interferon responses and TNF-α signaling via NFkB in monocytes in children with uncomplicated malaria
Authors: Morang’a Collins M. , Drake Riley S. , Miao Vincent N. , Nyakoe Nancy K. , Amuzu Dominic S. Y. , Appiah Vincent , Aniweh Yaw , Bediako Yaw , Bah Saikou Y. , Shalek Alex K. , Awandare Gordon A. , Otto Thomas D. , Amenga-Etego Lucas
Published: January 2025

Malaria causes significant morbidity and mortality worldwide, disproportionately impacting sub-Saharan Africa. Disease phenotypes associated with Plasmodium falciparum infection can vary widely, from asymptomatic to life-threatening. To date, prevention efforts, particularly those related to vaccine development, have been hindered by an incomplete understanding of which factors impact host immune responses resulting in these divergent outcomes. Here, we conducted a field study of 224 individuals to determine host-parasite factors associated with symptomatic malaria “patients” compared to asymptomatic malaria-positive “controls” at both the community and healthy facility levels. We further performed comprehensive immune profiling to obtain deeper insights into differences in response between the pair. First, we determined the relationship between host age and parasite density in patients (n = 134/224) compared to controls (n = 90/224). Then, we applied single-cell RNA sequencing to compare the immunological phenotypes of 18,176 peripheral blood mononuclear cells isolated from a subset of the participants (n = 11/224), matched on age, sex, and parasite density. Patients had higher parasite densities compared to the controls, although the levels had a negative correlation with age in both groups, suggesting that they are key indicators of disease pathogenesis. On average, patients were characterized by a higher fractional abundance of monocytes and an upregulation of innate immune responses, including those to type I and type II interferons and tumor necrosis factor-alpha signaling via NFκB. Further, in the patients, we identified more putative interactions between antigen-presenting cells and proliferating CD4 T cells, and naïve CD8 T cells driven by MHC-I and MHC-II signaling pathways, respectively. Together, these findings highlight transcriptional differences between immune cell subsets associated with disease phenotypes that may help guide the development of improved malaria vaccines and new therapeutic interventions.
Recycling cathode materials for lithium-ion batteries via Hydro-to-Cathode® method
Authors: Shim Jong Hyun
Published: January 2025

Due to the rising price and limited resource supply chain of Li [NixMnyCoz]O2 (x + y + z = 1) (NMC) cathode material, lithium-ion battery (LIB) recycling technologies have been emerging as the best solution to address the price issue. Mainly, conventional hydrometallurgy processes have been applied to the LIB recycling field in recognition of its value. One remarkable advantage of the hydrometallurgy method is that it serves as a bridge to enable the Hydro-to-Cathode® method. However, using recycled raw materials in the production of precursor cathode materials needs to be studied in parallel with the impurity (dopant) effect. The insufficient selective impurity removal technology leads to unexpected electrochemical properties in the final NMC cathode active material, which can be doped by several different impurities. Consequently, scrutinizing dopant elements (inorganic and organic) is critical if we want to consider the Hydro-to-Cathode® method as a major recycling process of NMC cathode material.
Analyzing critical success factors using blockchain based framework for intelligent transportation systems
Authors: Mutahhar Ahmad Yahya , Khanzada Tariq Jamil Saifullah , Shahid Muhammad Farrukh
Published: January 2025

This study examines the incorporation of blockchain technology into Saudi Arabia’s Intelligent Transportation Systems (ITS), concentrating on enhancing the bus permission procedure for religious mass gatherings in Makkah. The research illustrates how blockchain might improve the security and operational effectiveness of transportation management for major events. The research used a weighted significance methodology and Decision-Making Trial and Evaluation Laboratory (DEMATEL) analysis to identify the critical success factors (CSFs) influencing transportation at religious events. The research illustrates the strong interrelation of the CSFs, emphasizing the notable enhancement in transparency and efficiency in the approval and management processes using blockchain-based solutions. The research examines the impact of reformulated CSFs on the proposed blockchain-based transportation framework (BTF), emphasizing key domains such as people (P1), technology (P2), the environment (P3), and organization (P4). The findings indicate that blockchain-related CSFs exhibit the greatest influence, which is 21.62, while financial CSFs demonstrate the least influence of 0.25. This research significantly addresses current system limitations and stimulates wider blockchain usage inside Intelligent Transportation Systems by developing a thorough mathematical model. This paper presents a strategy framework for the successful management of large-scale transportation difficulties with blockchain technology, assuring optimum operations in organizational and environmental contexts.
Glial cells improve Parkinson’s disease by modulating neuronal function and regulating neuronal ferroptosis
Authors: Li Mengzhu , Chen Mengxuan , Li Haiyan , Gao Da , Zhao Lijun , Zhu Meiling
Published: January 2025

The main characteristics of Parkinson’s disease (PD) are the loss of dopaminergic (DA) neurons and abnormal aggregation of cytosolic proteins. However, the exact pathogenesis of PD remains unclear, with ferroptosis emerging as one of the key factors driven by iron accumulation and lipid peroxidation. Glial cells, including microglia, astrocytes, and oligodendrocytes, serve as supportive cells in the central nervous system (CNS), but their abnormal activation can lead to DA neuron death and ferroptosis. This paper explores the interactions between glial cells and DA neurons, reviews the changes in glial cells during the pathological process of PD, and reports on how glial cells regulate ferroptosis in PD through iron homeostasis and lipid peroxidation. This opens up a new pathway for basic research and therapeutic strategies in Parkinson’s disease.
Based on the MaxEnt model the analysis of influencing factors and simulation of potential risk areas of human infection with avian influenza A (H7N9) in China
Authors: Yang Zhao , Ren Zhong Da , Wang Jie , Dong Wen
Published: January 2025

Exposure to infected animals and their contaminated environments may be the primary cause of human infection with the H7N9 avian influenza virus. However, the transmission characteristics and specific role of various influencing factors in the spread of the epidemic are not clearly understood. Therefore, it is of great significance for scientific research and practical application to explore the influencing factors related to the epidemic. Based on the data of relevant influencing factors and case sample points, this study used the MaxEnt model to test the correlation between human infection with H7N9 avian influenza and influencing factors in China from 2013 to 2017, and scientifically simulated and evaluated the potential risk areas of human infection with H7N9 avian influenza in China. The simulation results show that the epidemic risk is increasing year by year, and the eastern and southeastern coasts have always been high-risk areas. After verification, the model simulation results are generally consistent with the actual outbreak of the epidemic. Population density was the main influencing factor of the epidemic, and the secondary influencing factors included vegetation coverage, precipitation, altitude, poultry slaughter, production value, and temperature. The study revealed the spatial distribution and diffusion rules of the H7N9 epidemic and clarified the key influencing factors. In the future, more variables need to be included to improve the model and provide more accurate support for prevention and control strategies.
Gut microbial composition associated with risk of premature aging in women with Yin-deficiency constitution
Authors: Zhai Yingying , Li Jing , Cao Yanqi , Li Yufei , Bao Xuejie , Liang Jinfeng , Liu Qi , Xia Yifan , Yu Ruoxi
Published: January 2025

Background

Yin-deficiency constitution (YinDC) refers to a traditional Chinese medicine concept, characterized by an imbalance state that includes an imbalance in the gut microbiota, resulting from a relative deficiency of Yin fluids within the body. In recent years, it has become apparent that the composition and structure of the gut microbiota play a significant role in the aging process. The imbalance of gut microbiota in YinDC may accelerate the aging process. However, the specific gut microbiota compositions involved in the YinDC premature aging process remain unknown.

Methods

In this study, we conducted a cohort study including 60 women with YinDC and BC to analyze their gut microbiota composition. We integrated 16S rDNA sequencing with machine learning methods to reveal the association between gut microbiota and premature aging in YinDC women.

Results

We found a significant difference in the composition of gut microbiota between the YinDC and the BC group. At the phylum level, Cyanobacteria and Synerobacteria only emerged in the YinDC group. At the genus level, Bacteroides, Bifidobacterium, Haemophilus, Alistipes, and Dialister showed higher abundance in the YinDC group. Bilophila, Eubacterium, and Aeromonas were the most significant indicators influencing the YinDC premature aging. The YinDC group had the most functional gene pathways associated with the metabolism.

Conclusion

Our study demonstrated that the gut microbiota was associated with premature aging in women with YinDC, potentially providing preliminary evidence and guidance for personalized anti-aging strategies.
Compound weather and climate extremes in the Asian region: science-informed recommendations for policy
Authors: Krishnan R. , Dhara Chirag , Horinouchi Takeshi , Gotangco Gonzales C. Kendra , Dimri A. P. , Shrestha M. Singh , Swapna P. , Roxy M. K. , Son Seok-Woo , Ayantika D. C. , Cruz Faye Abigail T. , Qiao Fangli
Published: January 2025

Anthropogenic climate change has led to rapid and widespread changes in the atmosphere, land, ocean, cryosphere, and biosphere, leading to more pronounced weather and climate extremes globally. Recent IPCC reports have highlighted that the probability of compound extreme events, which can amplify risk, has risen in multiple regions. However, significant gaps remain in our understanding of the drivers and mechanisms behind these events. This concept paper discusses compound events in the Asian region in the context of its unique and diverse geographical settings, and regional climatic features including the seasonal monsoons. Notably, Asia is the world’s most disaster-affected region due to weather, climate, and water-related hazards. Therefore, an integrated understanding of how climate change will impact compound events in this region is essential for effective forewarning and risk mitigation. This paper analyzes three typologies of compound events in the Asian region, illustrating their regional complexity and potential linkages to climate change. The first typology pertains to compound floods, for example, the devastating floods in the Indus River Basin and adjoining Western Himalayas during 2022 caused by the combined effects of heavy monsoon rainfall, intense pre-monsoon heatwaves, glacier melt, and modes of climate variability. The second typology relates to compound heatwave-drought events that have prominently manifested in East and South Asia, and are linked to large-scale drivers of the land-atmosphere–ocean coupled system and local feedbacks. The third typology relates to marine extremes involving the compounding effects of ocean warming, sea-level rise, marine heatwaves, and intensifying tropical cyclones. We identify key knowledge gaps in understanding and predicting compound events over the Asian region and discuss advances required in science and technology to address these gaps. We also provide recommendations for the effective utilization of climate information towards improving early warning systems and disaster risk reduction.
Study on its application and unstable risk subarea estimation method of mountainous traffic engineering’s spoil ground
Authors: Zhang Jihong , Dong Zhongji , Yin Xiaotao , Yang Min
Published: January 2025

Residues disposal areas with different quantities and scales are produced with the traffic engineering construction in mountainous areas construction, whose environment security threats need to be termly estimated. Countermeasures are adopted by estimated results, and safety risk management and control of waste dump engineering are realized. Based on field research and data access, stage characteristics of the process is summarized. Then force equilibrium and moving balance equation of waste dump sliding body at different stages are formed. So, risk grades and subarea labeled by red, yellow and green colors based on different moving distances are established. Finally, traditional way and the failure risk subarea assessment method are compared in practice, which proves feasibility of the method. Main conclusions are as following. 1) Fail process of mountainous highway waste slag slope is divided into initial limit equilibrium stage, speed-up downslide stage on slipping surface in which the sliding friction coefficient continues to decrease with acceleration, and speed-down downside stage on ground surface in which the sliding friction coefficient continues to increase with the deceleration. 2) Force balance equation at initial stage, downslide force formula at speed-up downslide stage and anti-slide force formula at speed-down downslide stage are presented by sliding body mechanical model on slipping surface and ground surface. Maximum moving velocity formula at the toe of the slope is established. And moving distance of waste dump sliding body is induced by energy balance equation. 3) Minimum and maximum of moving distance are computed under maximum and minimum of sliding friction coefficient conditions. According to these distances, safety threats of fail waste dump are classified into three grades: red region being high risk locates, yellow region being middle risk locates, green region being low risk. Relying on practical residues disposal area, disadvantage and advantage of the method and traditional method are compared. Found that mechanical mechanism of the method is simple, forces and parameters are all unified in balance equations, which meets to practical waste dump fail process. And the method does good to guiding mountainous residues disposal area unstable risk assessment.
Exploring family models and SDG number five in picture books. Dialogical alternatives for secondary education
Authors: López-Valero Amando , Hernández-Delgado Lourdes , Jerez-Martínez Isabel , Encabo-Fernández Eduardo
Published: January 2025

Introduction

This contribution addresses the controversy that often surrounds the educational treatment of new family models. The literature, as a medium of fiction based on reality, reflects social changes, including the organization of families. Promoting gender equality—Sustainable Development Goal (SDG) number five (United Nations)—is closely linked to understanding these new family structures. In this context, picture books—powerful literary resources that combine images and words—should be used to expose students to new realities and raise awareness of diversity, thereby fostering tolerance and respect.

Method

This study analyzes several picture books, including classics like King and King and more recent titles like Well done Mummy. The analysis will focus on their format and content to determine their suitability for secondary school classrooms, discuss family models, and raise awareness, potentially changing attitudes. Following the analysis, we explore how to incorporate these books into educational sequences, highlighting the use of dialogical discussions to promote critical thinking.

Results

The results of this contribution will include a list of suggested picture books, an evaluation of their suitability, and proposed didactic strategies.

Discussion

These aspects will strengthen the classroom treatment of this controversial topic, helping students grow holistically through axiological aspects and the development of SDG number five: gender equality. Additionally, this study will confirm the relevance of using picture books in the classroom within the context of liquid modernity, where audiovisual elements are key motivators for students.
Cognitive load and neurodiversity in online education: a preliminary framework for educational research and policy
Authors: Le Cunff Anne-Laure , Martis Brandon-Lee , Glover Caitlin , Ahmed Emily , Ford Rhian , Giampietro Vincent , Dommett Eleanor J.
Published: January 2025

This theoretical paper presents the development and analysis of an inclusive educational framework designed to manage cognitive load for neurodivergent students in online learning environments. Drawing from cognitive load theory and neurodiversity studies, the framework is based on existing literature, empirical work conducted by the authors, and iterative feedback from a participatory research advisory board. Taking a neurodiversity-informed perspective that focuses on interventions addressing challenges common across a range of conditions, it identifies six critical areas that might impact cognitive load in online learning for neurodivergent students: format, environment, delivery, instruction, support, and research (FEDIS+R). To assess the external factors influencing the potential implementation of the framework and its place within the broader landscape of inclusive education, a PESTEL (Political, Economic, Social, Technological, Environmental, and Legal) analysis was conducted. The analysis highlights challenges such as resource disparities, institutional commitment to inclusion, and legal requirements for accessibility, which may affect the adoption of the framework. Given the evolving nature of both cognitive load theory and neurodiversity studies, future research directions are suggested to evaluate its effectiveness across diverse educational contexts. This paper contributes to the growing body of knowledge on neurodiversity in education and offers practical recommendations for educators and policymakers seeking to create inclusive online learning environments.
The impact of the MOOC based on the flipped classroom methodology to increase the level of information and information literacy competence in primary school teachers
Authors: Fernández-Otoya Fiorela , Bravo Jessie , Pérez-Postigo Gerber , Alcázar-Holguin Manuel Alfredo , Loaiza Chumacero Sandra Cecilia
Published: January 2025

We live in an increasingly digitalized and competitive world, so the use of technological resources in continuing education is essential. The objective was to determine the impact of the MOOC based on the flipped classroom methodology on the level of information competence and information literacy in primary school teachers. The approach was quantitative, pre-experimental design. The sample consisted of 810 teachers from the Lambayeque region. After the MOOC application, it was found that the competency of navigation, search and filtering of information, data and digital content obtained the highest score, with 2.84 in the pretest and 3.67 in the posttest on a scale of 1 to 5. The conclusion is the need to train teachers so that they are able to respond effectively and efficiently to the new challenges of this digital society.
A culturally relevant, imbued, and sustaining pedagogy framework for culturally connected math curriculum
Authors: Luecke Danny
Published: January 2025

This article introduces the CRISP (Culturally Relevant, Imbued, and Sustaining Pedagogy) framework in the context of a three-course sequence, “Indigenous Math I, II, and III,” taught at Turtle Mountain College. These three courses seek to revitalize mathematical ways of knowing embedded within the Turtle Mountain language(s) and culture(s). The Indigenous Math framework and Indigenous Math Education framework guide these three courses, as well as the Secondary Math Education bachelor’s degree program that spurred development of these courses. Discussing the relationship (i.e., connections, similarities, differences) between Western math and Indigenous math is central to these courses. The CRISP framework extends this discussion by describing four significant components of revitalizing and teaching Indigenous math. Multiple Indigenous math examples are shared as evidence for the value of the CRISP framework.
A synchronous compression and encryption method for massive electricity consumption data privacy preserving
Authors: Zhao Ruifeng , Lu Jiangang , Yu Zhiwen , Zeng Kaiwen
Published: January 2025

The demand for fine-grained perception of electricity usage information in the new power system is continuously increasing, making it a challenge to address potential unauthorized data access while ensuring channel security. This paper addresses privacy in power systems requiring efficient source-load interactions by introducing a novel data compression synchronous encryption algorithm within a compressed sensing framework. Our proposed algorithm uses a ternary Logistic-Tent chaotic system for generating a chaotic measurement matrix, allowing simultaneous data compression and encryption of user-side voltage and current data. This mitigates high-frequency sampling overload and ensures data confidentiality. The implementation of a joint random model at both compression and reconstruction stages eliminates the need for key transmission, reducing management costs and leakage risks. The proposed algorithm was validated using the PLAID dataset, demonstrating that the time required for a single encryption-decryption operation can be reduced by up to 81.99% compared to the asymmetric RSA algorithm. Additionally, compared to the symmetric AES algorithm, the proposed method significantly enhances confidentiality.