bluuebunny/crossref_metadata_2025 huggingface dataset:
Readiness for self-directed learning among nursing students in a medical college, Chitwan
Authors: Singh Indu , Paudel Binita
Published: April 2020

Background: Self-directed learning is a type of instructional strategy where students take charge of their learning process. Self-directed learning is learning approach where learners are responsible towards learning which helps students think critically and perform task confidently. The skills that are learned through self-directed learning remain lifelong and helps to provide patient care in effective way and uplifting the nursing profession. This study was conducted to identify the readiness for self-directed learning among nursing students in Chitwan Medical College.

Methods: A descriptive cross-sectional study design was adopted. Sample size was 107 nursing students from Bachelor in science of nursing and Bachelor in nursing science program. They were selected by using probability, stratified, simple random technique. A standardized tool (Self Directed Learning Readiness Scale) was used to collect data. Data were analyzed by using descriptive statistics and inferential statistics.

Results: More than two-third of the nursing students were ready for self-directed learning. The mean score of self control was higher than the mean score of self-management and mean score of desire. The level of the readiness for self-directed learning was significantly associated with age (p=0.036), ethnicity (0.036) and most prefer resource (p=0.010).

Conclusions: Self-directed learning helps for self control towards their learning and enable students move forward towards their career goal. So, the faculties need to focus on the selection resources for learning that help to create desire for learning and promote self-directed learning skills among nursing students.
Proximity of mandibular third molar roots with inferior alveolar canal: a radiographic study
Authors: Singh Ashutosh Kumar , Khanal Nikita , Dhungel Safal
Published: April 2020

Background: Mandibular third molar’s roots have close proximity to the inferior alveolar canal (IAC) and nerve. Inferior alveolar nerve injuries have been observed to occur more frequently when there is radiographic evidence of close contact of third molar roots to the IAC. Orthopan­tomogram is one of the commonly used diagnostic tools for evaluating the relationship between these two structures. There is lack of data regarding prevalence of these radiographic signs in Nepalese population. It was required to assess the reliability on the radiographic signs of relation­ship between the IAC and the third molar roots, to establish IAC as risk indicators for IAC exposure during extraction.

Methods: A single centre cross-sectional descriptive study was designed where demographic data and radiographic signs of third molar roots proximity to IAC were obtained from imaging software records and descriptive analysis was performed with SPSS version 20.

Results: One or more radiographic signs were observed in 49.6% of mandibular third molars. In­terruption of white line followed by narrowing of canal and darkening of roots was observed in decreasing order of frequency and no statistically significant association between sex, age and side of impacted third molar with presence of radiographic signs.

Conclusions: Presence of one or more radiographic signs of proximity of mandibular third molar roots with IAC in nearly half of the cases. Clinicians should be aware of risk of nerve injury on pres­ence of these signs. Further investigation with cone beam computed tomography to rule out any nerve injury risk should be adopted into practice.
Assessment of Nepalese prosthodontist’s attitude towards morphological completeness of dental arches in partially dentate older patients
Authors: Poudel Sabina , Shrestha Prabhat , Acharya Lochana , Poudyal Sijan
Published: April 2020

Background: Complete dentition is not always appropriate for old aged medically compromised and financially weak individuals. It is the dentist to decide what minimum number of teeth should be restored to have the proper oral function. The aim was to find out the opinion of prosthodon­tists of Nepal regarding the suitability of shortened dental arch as treatment modality and how frequently is this treatment choice for an old aged Nepalese patient.

Methods: A pretested close ended questionnaire was usedin this study.After taking ethical clear­ance from Nepal Health Research Council, online questionnaire was sent to the participants along with the consent. Analysis was done using SPSS (version 21) statistical software package. Descrip­tive statistics was used. Percentage and frequencies were calculated.

Results: Among respondents, 96.2% (n=51) had heard about shortened dental arch therapy but 3.8 % (n=2) had never heard about it. Forty-two (79.2%) do support shortened dental arch. Eleven (20.8%) do not favorshortened dental arch. Their main reason for replacing molars was to improve masticatory function.Instead of shortened dental arch,n=5(45.5%) prefer cast partial denture and 6(54.5%) advice implant supported fixed prosthesis. Among Prosthodontists who recommended shortened dental arch therapy, eight (19.1%) always advised patients not to replace molars. Twen­ty-four (57.1%) prosthodontists who support shortened dental arch therapy mentioned chewing function in shortened dental arch patients as satisfactory.

Conclusions: Majority of Prosthodontists agree that shortened dental arch is a suitable treatment option for older people in developing countries like Nepal. But the treatment is not employed in clinical practice as required.
Female autonomy and fertility pattern among women working in formal sector in Kathmandu valley
Authors: Singh Neeti , Pandey Srijana , Sherpa Ang Tshering , Tamrakar Nijina , Chitrakar Sunil
Published: April 2020

Background: Fertility rate is declining more among women with higher education around the world. This may be due to number of years spent for achieving higher degree, choice of work and age at marriage. With growing autonomy of urban women and late age at marriage increases high risk pregnancy and declines number of children leading to decrease in young population. So, this study was done to explore the fertility pattern and associated factors among working women at formal sectors.

Methods: An observational study was done among women working at formal sectors within Kath­mandu valley. A respondent driven sampling was used to achieve total 101 sample size. The study period was October and November 2019.

Results: Median age of the participants was 40 and median age at marriage was 26.62 years. The association between level of education and age at marriage was statistically significant. The median age of pregnancy of the participants were 27 years and 58.4% of women had only one live child. Average number of desired children was 1.69 whereas actual number of children was 1.32. The gap between desired and number of children is statistically significant. Only 35.6% reported to have used some form of contraceptive devices as the measure of family planning.

Conclusions: Fertility behavior of working women is not completely influenced by their working status except for higher age at marriage, pregnancy and desired number of children which in long term may affect in the growth of country.
An unusual cause of intraoperative high airway pressure and ventilator failure: message to be learned
Authors: Shrestha Anil , Parajuli Bashu Dev , Tiwari Pradip , Limbu Trishant
Published: April 2020

Failure of ventilation of an anesthetised patient due to problems in mechanical ventilator is not uncommon. The proper functioning of machine should be ensured before anesthetising a patient by the automated checking system or manually by the attending anaesthesiologist. However, sudden malfunction of some system of the machine during operation may cause the ventilator to stop risking the patient’s life. About one third of the equipment problems are due to anesthesia machine and one quarter of the problems are due to human error. We present a case of malfunction of anesthesia ventilator due to an unusual cause of blockage of anesthesia gas scavenging system.
Ascaris infection, a rare cause of necrotizing pancreatitis in a child
Authors: Yadav Aditya Prakash , Karki Rishi Kumar , Rai Binod Kumar
Published: April 2020

Necrotizing pancreatitis is a very rare in children and is associated with high morbidity & mortality rates. We report a case of 5yr old boy who presented with upper abdominal pain, vomiting and non-passage of stool for 1day. After resuscitation and investigating the child, a provisional diagnosis of biliary ascariasis (BA) with acute pancreatitis was made. The child developed peritonitis after 2 days of admission and exploratory laparotomy was planned. An intraoperative diagnosis of necrotizing pancreatitis was made and the child was successfully managed.
Amoxicillin Induced Behavioral Neurotoxicity and Histopathological Changes in Organs of Albino Rats
Authors: Paudel Sabita , Aryal Bijay , Ranabhat Sunita
Published: April 2020

Background: There are various adverse drug reactions of penicillin. Neurotoxicity is attracting the attention of researchers all over the world. It also affects other organs like liver, kidney, heart and testes

Methods: The study was conducted at pharmacy and pharmacology department of Gandaki Medical College (GMC) from January till April, 2018. Albino rats were divided six each in test and control group. Tests were administered amoxicillin 90mg/kg/d and control with distilled water for 10 days. After 10 days, rats were tested for neurotoxicity with rota-rod (RR) and modified forced swim test (MFST). They were then sacrificed under anesthesia, organs were dissected and sent for histopathological investigation.

Results: The latency to fall from RR apparatus decreased significantly in test rats than control. (P value = 0.0001) In MFST, immobility time was significantly increased than control (P value = 0.0001). Swimming time(ST) was significantly decreased (P value = 0.001) and climbing time (CT) was not significantly altered in test rats than control (P value = 0.352). The liver enzyme, AST and ALT were significantly increased in the test rats (TR) as compared to controls. (P value 0.049 and 0.001 respectively) Brain of test rats (TR) showed shrunken neurons surrounded by perineuronal vacuolations, liver and kidney showed degenerative changes. Vacuolations and pyknotic cells were seen in spermatogonic cells.

Conclusions: Neurotoxic effects were seen in test rats which recommends regulation of the administration of high dose of penicillin.
Ultrasonography and Magnetic Resonance Cholangiopancreatography in Patients with Obstructive Jaundice
Authors: Chhettri Pramod , Rana Hari
Published: April 2020

Background: Jaundice is a common presenting symptom in patients with hepatobiliary disease. It can be categorized into medical and surgical jaundice and it is important to differentiate due to the different treatment options

 Methods: In this cross sectional study from Jan 2017 to June 2018, 84 consecutive patients with          obstructive jaundice who underwent initial USG and then MRCP were included and their respective diagnosis compared keeping surgery and/or histopathology as the gold standard for final diagnosis.

 Results: Out of 84 patients, 67.9% were females and 32.1% were males. The most common cause for obstructive jaundice was benign in 72.6% and malignancy in 27.4%. Among the benign lesions            choledocholithiasis was the most common (57.4%) followed by pancreatitis  (26.2%).                      Cholangiocarcinoma was the most common malignant cause (47.8 %) followed by periampullary  carcinoma (26.2%). The sensitivity and specificity of USG in benign lesions was 67.2% and 87%  respectively, and in malignancy 56% and 95% respectively. Similarly sensitivity and specificity of MRCP for benign lesions was 95.2% and 90.9% respectively, and for malignancy 95.75% and 98.45%respectively. Overall diagnostic accuracy of USG in benign and malignant causes was 76.62% and 84.52% respectively. Similarly overall diagnostic accuracy of MRCP for benign and malignant causes was 93.98% and 97.6% respectively.

 Conclusions: USG is a good modality for Initial screening and for differentiating  medical and surgical cause of jaundice. MRCP is a better modality with higher sensitivity, specificity and diagnostic accuracy for detecting pathology as compared to USG.

Keywords: MRCP; obstructive jaundice; USG.
Prevalence and Antibiogram of Acinetobacter Species Isolated from Various Clinical Samples in a Tertiary Care Hospital
Authors: Rajkumari Sanjana , Pradhan Shanti , Sharma Damodar , Jha Brajesh
Published: April 2020

Background: Acinetobacter species has emerged as a significant hospital pathogen, and are becoming        increasingly drug resistance. They cause outbreaks in intensive care units and health care units.

Methods: A cross-sectional study was conducted to determine the prevalence and antibiotic susceptibility pattern of Acinetobacter spp isolated from various clinical samples collected from patients admitted in various wards and intensive care units of the hospital over a period of one year (March 2018 to Feb 2019).  

Results: Out of 2,623 samples, 1,201(45.78%) yielded significant growth and out of these positive cultures, 138(11.49%) Acinetobacter spp were isolated. Majority of isolates 24(17.39%) were isolated from General intensive care unit (GICU). Maximum sensitivity of Acinetobacter spp was seen towards polymyxin B 138(100%) and colistin 138(100%), followed by tigecycline 127(92.02%). Hundred and one (80.43%) isolates were found to be multidrug resistant.  

Conclusions: Acinetobacter isolates showed multidrug resistant pattern mostly in inpatients. To avoid resistance, antibiotics should be used judiciously. There is also an urgent need for emphasizing the       importance of hand washing and use of disinfectants in prevention of transmission of infection in health care setup.

Keywords: Acinetobacter spp; prevalence; antibiotic resistance; intensive care units; multidrug           resistance.
Relation of Steroid on Linear Growth Velocity with Biochemical Bone Markers in Children with Nephrotic Syndrome in a Teaching Hospital, Central Nepal
Authors: Pan Atanu , Jana Debarshi
Published: April 2020

Background: Nephrotic Syndrome is the clinical manifestation of glomerular diseases associated with heavy (nephrotic range) proteinuria. This study   was done to compare biochemical bone markers in nephrotic children on steroid therapy and the linear growth velocity in children with nephrotic syndrome receiving steroid with that of  known available reference standard for children of same age and sex groups

Methods: A hospital based comparative study   was conducted in the Department of Pediatrics, College Of Medical Sciences, Bharatpur, Nepal among 40 Study group and 40 Comparatvie group by taking the data from 2014 to 2018.

 

Results: We found that in study   group, the Mean Vitamin D of patients was 12.6293 ± 3.4974 which was low. Present study  found that in Study   group, the Mean serum Ca (Mean± SD.) of patients was 6.8000 ± .9672. In comparative group, the Mean serum Ca (Mean± SD.) of patients was 9.6907 ± .9218. Difference of Mean serum Ca vs. group was statistically significant (p<0.0001).

Conclusions: We found that the Mean albumin significant lower in study   group compared to comparative group but total cholesterolsignificant higher in study   group. Vitamin D and calcium were low in Study   group which was statistically significant.
Helicopter Parenting, Parental Psychological and Behavioral Control Revisited: Assessing Constructs Across the United States and South Korea
Authors: Zhang Yue , Hwang Woosang , Jung Eunjoo , Kim Seong Hee , Sin Hye Lim
Published: April 2020

This study examined the construct validity of helicopter parenting by comparing this construct with other close relevant constructs of psychological control and behavioral control, using a cross-cultural comparison approach. Data were collected from college students in the United States ( N = 380) and South Korea ( N = 204). Multi-group structural equation modeling analyses indicated that helicopter parenting was a correlated yet separate construct, compared with psychological control and behavioral control in both the US and Korea samples, suggesting a convergent and discriminant validity cross-culturally. Several items in helicopter parenting, psychological control, and behavioral control were more associated with Korean contexts. This study contributes to the extant literature by investigating the validity issue of helicopter parenting in a cross-cultural context, providing an in-depth understanding of parental control practices across Eastern and Western cultures.
Do Only-Children Communicate Better Than Non-Only Children?
Authors: Wang Wei , Zhang Jie , Hennessy Dwight A. , Yin Wenqiang
Published: April 2020

Since the implementation of the One-Child Police in China in 1979, great concern has been raised about the physical and psychological development of “only-children.” Some researchers believe that only-children may have difficulty with social skills, which include communication ability, because they would lack early sibling interactions. The aim of the present study was to explore the communication ability of only-children compared to children raised with siblings. We administered the self-developed Interpersonal Communication Ability Assessment Scale, which had been previously validated and refined, to 1,376 medical students in China. Results showed that when considering communication ability on its own, there were slight differences found between only-children and non-only-children. However, this difference was no longer significant when other independent variables were included in a hierarchical linear regression. This might be due to the fact that only-children have more highly educated parents, with more high-status careers, and greater family income that might provide greater social and educational opportunities, which might then increase communication abilities.
CRITICAL ANALYSES OF NATURAL LANGUAGE PROCESSING (NLP) IN UNDERSTANDING SEMANTICS
Authors: Farida Huseynova
Published: April 2020

Today, language understanding systems do quite many useful things with processing natural language, even they are able to process the data much faster than humans are. Nevertheless, they do not have the same logical understanding of natural language yet as humans have and the interpretation capabilities of a language understanding system depending on the semantic theory is not sufficient in all aspects. The research is centered on some of the important issues that arise using it in natural language processing.
ИССЛЕДОВАНИЕ СЕЙСМОСТОЙКОСТИ ГРУНТОВЫХ ПЛОТИН ОТ ДЕЙСТВИЯ МНОГОКРАТНЫХ СЕЙСМИЧЕСКИХ ВОЗДЕЙСТВИЙ, СООРУЖЕННЫХ В ГОРНО- СКЛАДЧАТЫХ РЕГИОНАХ
Authors: Ани Геворгян  , Роберт Минасян
Published: April 2020

The problem of seismic stability of homogeneous earth dams constructed in complex geohydrodynamic regions has been solved. The calculations are performed using from the finite element method. Given the great extent at the base of such dams, the general equation of their motion is solved taking into account the well-known “traveling wave” method. It is shown that the offset of the existing viscous-plastic properties of earth dams already under the influence of a one-time strong seismic impact in them residual deformations arise, which subsequently develops even with weak earthquakes. This circumstance must be taken into account when designing such dams.
TECHNICAL FEATURES OF COLOUR SYSTEM DEVELOPMENT IN ELECTRONIC ADVERTISING
Authors: Hussain Abdulalee Falh Almnshdawy
Published: April 2020

The objective of the work is to analyze the technical features of the development of colour system in electronic advertising and to identify ways of solving the main problems.Research methodology. The methodology of this research paper is based on a project approach, which involves the analysis and identification of problems in the development of colour systems in electronic advertising. Electronic advertising has its distinct features, which are caused by the process of its creation. The specifics of the work required the involvement of various theoretical sources on colouring, the psychology of colour perception, computer modelling, as well as statistics.The scientific novelty of this study is to identify the most problematic moments in the perception of electronic advertising and find ways to solve them, i.e. optimization of the colour system in accordance with the characteristics of the target audience and the nature of the web page design.
ВПЛИВ МОЛЕКУЛИ ОПІОЇДНОГО АНАЛЬГЕТИКА У СПЕКТРІ ДІЇ НА СТРУКТУРУ ОРГАНІВ
Authors: Івасівка Х. П.  , Пальтов Е. В.  , Кривко Ю. Я.
Published: April 2020

The aim of our work was to study scientific information and statistics on pathomorphological manifestations in tissues, organs and systems of the body when exposed to a molecule of opioid drugs in the aspect of experimental research.
ИСПОЛЬЗОВАНИЕ МАНУАЛЬНОЙ ТЕРАПИИ В СОЧЕТАНИИ С УДАРНО-ВОЛНОВОЙ ТЕРАПИЕЙ У ПАЦИЕНТОВ С АНКИЛОЗИРУЮЩИМ СПОНДИЛИТОМ
Authors: Сергей Франк  , Михаил Франк  , Георгий Франк
Published: April 2020

Ankylosing spondylitis is a chronic systemic disease of the connective tissue which affects primarily joints and ligaments of the spine, peripheral joints and internal organs, causing progressive development of limited spinal mobility due to ankylosing of epiphyseal joints, formation of syndesmosis and calcification of vertebral ligaments. There are currently no methods that can completely cure or stop the progression of ankylosing spondylitis, however, manual therapy combined with shock- wave therapy is able to quickly, non-invasively, effectively, economically, safely and without side effects support patients, improving their quality of life, prolonging the duration of the remissions, reducing the frequency of relapses, significantly delaying the development of structural damage and the progression of bone ankylosis. This study discusses the effect of manual therapy combined with shock wave therapy on ankylosing spondylitis resistant to other treatments.
ОГЛЯД ЗАГАЛЬНОПРИЙНЯТИХ МЕТОДИК ЛІКУВАННЯ ОНІХОКРИПТОЗУ
Authors: Циганенко О. О.
Published: April 2020

Introduction: According to existing views, the ingrown nail is one of the diseases that often occurs in surgical practice and causes considerable suffering in patients and significantly restricts them in the performance of professional duties; reduces the physical activity and psychoemotional tone of the patient.Aim: Given that the number of patients with ingrown nail is steadily increasing, that today there are about 200 surgeries in the ingrown nail, and many of them do not take into account the etiological and pathogenetic components. The author's team decided to research and review common methods of treatment of ingrown nailsMaterials and methods: A library fund was worked out regarding the problem of ingrown toenails. the workings out of clinics of Ukraine and other countries were worked outResults: Today, there are more than 150 methodological approaches to treating ingrown nail in the world. None of these procedures is Ideal for Achieving aesthetic results with low cost, recurrence and complication rates. Conclusions: The identified problems lead to the need to find a new less traumatic and economical method of treatment of ingrown nail, which will be characterized by rapid recovery of the patient and reduction of possible relapses.
SCHOOL BUILDING PLANNING. MAIN TYPES OF SYSTEMS (PLANS) OF SCHOOL BUILDINGS
Authors: Elitsa Ivanova
Published: April 2020

How to Design School Buildings? Student(s), their number and age have the gratest impact on the school buildings;• To plan a school well, it must first be clear which age groups of students it will be for;• How many students will be there in each age group;• How many classes in each grade will be in the building.Following the study of children of various age groups, looking at the specifics of emotional development and various physical characteristics, it becomes clear to a large extent what is necessary to make them feel good in the school building.The parameters of the individual rooms and buildings for educational activity are also determined on the basis of the applicable rules for town planning, the regulations for designing buildings and facilities, and the standards related to school buildings, hygiene standards and fire construction and technical requirements.The complex study of all elements of the building, their interrelations, as well as the number and age of the students, in the context of the urban planning parameters and the requirements of each individual employer, determine the area and scale of design of the school buildings. Taking into account also the recent studies and trends for the good functioning of this type of buildings, a complex composition of elements, parameters and conditions may be obtained.
ДЕРЖАВА В СИСТЕМІ СОЦІАЛЬНОЇ БЕЗПЕКИ В УКРАЇНІ: ІНСТИТУЦІЙНИЙ АСПЕКТ
Authors: Ольга Тиха
Published: April 2020

The purpose of the article is to reveal the role of the state in the field of social protection of the population, to analyze the tendencies of development of budget financing of social security in Ukraine and to offer ways to improve the reform of the sphere of social protection of the population. The article describes the priority directions of the activity of the state and institutional features of the interaction of the legislative and executive power in the field of social protection, developed an adaptive model of state regulation of the sphere of social protection in the context of decentralization, analyzed the dynamics of spending on social protection and social security.
THE PHENOMENON OF «MASS CONSCIOUSNESS» IN E. FROMM'S PHILOSOPHY
Authors: Habriielian A.
Published: April 2020

In this article, the author considered the concept of «Mass Consciousness» in the philosophy of Erich Fromm. The phenomenon of «Mass Consciousness» was studied from the standpoint of E. Fromm’s «Humanistic Radicalism», and was analyzed in comparison with classical Freudian psychoanalysis and other prominent thinkers of the twentieth century. It was found that according to Erich Fromm's social psychoanalysis, aggression is the result of social exclusion, mass consciousness, and conformism. The prevention of these phenomena can only be realized by a healthy humanistic society, in which faith, hope, love, understanding, sanity, mutual respect, empathy that cannot be explained by human instincts.
AN ATTEMPT TOWARDS THE APPROPRIATE METHODS FOR QUALITATIVE RESEARCH
Authors: Huseynova Arifa
Published: April 2020

An analysis of research process indicates that it comprises in combination, the following elements: creative mentalities, properly defined problems, semantic problem –solving procedures, and certain types of possible solutions. All these elements are necessary and sufficient. Therefore, the most efficient relative utilization of each will make for the most desirable research procedure in any given application. The purpose of this paper is to discuss possible principles to be used in arranging these elements in an efficient manner, which will be useful in comprehending the present practice and the future of research. It should be noted at the start that these principles, intuitively and deductively inferred from an investigation of the characteristics of the research elements are to be considered tentative; the implication is not that they are necessarily invariant in research, but that the elements from which they stem are the same within any reference frame.
КЛАССИФИКАЦИЯ И ТЕНДЕНЦИИ РАЗВИТИЯ МЕЖДУНАРОДНЫХ ДОКУМЕНТОВ В СФЕРЕ ОБЕСПЕЧЕНИЯ И ЗАЩИТЫ ПРАВ ЖЕНЩИН
Authors: Фируза Хамдамова
Published: April 2020

The article is devoted to the classification of international documents in the field of ensuring and protecting the rights of women. The author systematizes them for several reasons, namely: depending on the subject who accepted the document, according to its legal nature, on the range of issues regulated by the document, its geographical scope. The author also raises the question of the reasons for the ineffectiveness of some documents on women's rights, in particular, the issue of reservations and cultural relativism.Thus, today there is a huge array of international documents on the rights of women, which are a fairly solid legal basis for effectively ensuring the rights of women. These documents are adopted in various forms - in the form of declarations, recommendations, conventions and programs or strategies of actions, that is, in the form of documents of a mandatory or recommendatory nature. An analysis of their content made it possible to highlight the most priority areas of international legal cooperation in the field of ensuring the rights of women, namely, maternity protection, ensuring equality in the family and the world of work, and protecting women from violence. More and more documents are being adopted in order to protect vulnerable layers of women facing multiple discrimination. The adoption of documents on the protection of the most vulnerable categories of women, that is, women exposed to multiple discrimination, is one of the trends in the development of international legal standards on women's rights.
REPARATIVE OSTEOGENESIS IN NORMAL STATE AND UNDER CONDITIONS OF IODINE DEFICIENCY
Authors: Kovalchuk P. Ye.  , Gasko М. V.  , Tulyulyuk S. V.  , Shutka V. J.
Published: April 2020

The study presents the results of investigation of iodine deficiency condition on the bone tissue and healing post-traumatic bone defects under conditions of iodine deficiency.The experimental part of the study was performed on 63 randomized brand albino male rats of 3-month age. Peculiarities of the reparative osteogenesis were studied on the model of a traumatic injury simulated one-type in the proximal meta-diaphysis of the femoral bone irrespective of the experimental conditions in the frontal plane in the form of perforated defect. The defect was made by means of a drill 1mm in diameter.The results of the study are indicative of a negative effect of iodine deficiency produced on reparative osteogenesis manifested by inhibition of the process and associated with disorders in the formation of osseous regeneration, deterioration of the structural-functional state of the osseous tissue, development of degenerative-necrotic changes in the osseous tissue and epiphyseal cartilage.
PHYSIOLOGICAL AND REPARATIVE OSTEOGENESIS IN THE NORM AND UNDER CONDITIONS OF SELENIUM DEFICIENCY
Authors: Kovalchuk P. Ye.  , Tulyulyuk S. V.  , Biryuk I. G.
Published: April 2020

The study presents the results of investigation of selenium deficiency condition on the bone tissue and healing post-traumatic bone defects under conditions of selenium deficiency.The experimental part of the study was performed on 63 randomized brand albino male rats of 3-month age. Peculiarities of the reparative osteogenesis were studied on the model of a traumatic injury simulated one-type in the proximal meta-diaphysis of the femoral bone irrespective of the experimental conditions in the frontal plane in the form of perforated defect. The defect was made by means of a drill 1mm in diameter.The results of the study are indicative of a negative effect of selenium deficiency produced on physiological and reparative osteogenesis manifested by inhibition of the process and associated with disorders in the formation of osseous regeneration, deterioration of the structural-functional state of the osseous tissue, development of degenerative-necrotic changes in the osseous tissue and epiphyseal cartilage.
ОПЫТ ЛЕЧЕНИЯ БОЛЬНОГО С ЭКССУДАТИВНЫМ ПЕРИКАРДИТОМ, ВОЗНИКШЕГО НА ФОНЕ КОЛОРЕКТАЛЬНОГО РАКА
Authors: Бойко В. В.  , Тамм Т. И.  , Бучнева О. В.
Published: April 2020

In the article presented the results of the treatment of pericardial effusion in a patient with sigmoid colon cancer. The pathological process in the pericardial cavity was asymptomatic and was discovered as an accidental find during a preoperative examination before surgery on the abdominal organs. The importance of timely diagnosis of such a serious and rare complication is shown. The presence of pericardial effusion in a patient with colorectal cancer changed the treatment tactics and forced to shift the focus of surgical interventions. This helped to reduce the risk of major surgical intervention on the abdominal organs and a favorable outcome for the patient.
ВПЛИВ МОЛЕКУЛИ ОПІОЇДНИХ ПРЕПАРАТІВ НА ПАТОМОРФОЛОГІЧНУ ДЕЗОРГАНІЗАЦІЮ ОРГАНІВ ТА СИСТЕМ
Authors: Івасівка Х. П.  , Пальтов Е. В.  , Кривко Ю. Я.
Published: April 2020

The aim of our work was to study scientific information and statistics on pathomorphological manifestations in tissues, organs and systems of the body when exposed to a molecule of opioid drugs.
УЛЬТРАСТРУКТУРА ТКАНИН ПАРОДОНТА НАПРИКІНЦІ ДРУГОГО ТИЖНЯ ЕКСПЕРИМЕНТАЛЬНОГО ОПІОЇДНОГО ВПЛИВУ
Authors: Фік В. Б.  , Ковалишин О. А.  , Пальтов Є. В.  , Кривко Ю. Я.
Published: April 2020

The following work is aimed at the study of submicroscopic disorganization in periodontal tissues with a two-week action of an opioid analgesic in an experiment. The aim was achieved by means of ultrastructural imaging of the cellular components of the mucous membrane of the gums and links of the hemomicrocirculatory bed. Ultrastructural preparations were prepared according to the conventional method. The conducted research provide a morphological basis to trace, at a more distant date, submicroscopic changes in soft periodontal tissues in dynamics against the background of a gradually increasing dose of opioid analgesic in the experiment.
ДИСНЕЙРООНТОГЕНЕТИЧНІ ДЕТЕРМІНАНТИ ПОРУШЕНЬ КОМУНІКАТИВНО-МОВЛЕННЄВОЇ ДІЯЛЬНОСТІ У ДІТЕЙ ДОШКІЛЬНОГО ВІКУ НА ЕТАПІ АНТЕНАТАЛЬНОГО РОЗВИТКУ
Authors: Наталія Лопатинська
Published: April 2020

The article is devoted to the study of the influence of dysontogenetic determinants (factors) of antenatal period on the formation and development of communicative and speech activity of a preschool child with different types of linguistic dysontogenesis. To achieve the purpose of the article, the following methods were used: theoretical (comparison, generalization and systematization of the results of diagnostic researches), empirical (diagnostic: standardized interviews, questionnaires, tests, analysis of medical documentation; observational: direct and indirect monitoring, protocoling); statistical (the establishment of the discrepancy with Fisher's multifunctional statistical criterion (Fisher's angular transformation)). Disneurotonogenetic determination of the main causes of communicative and speech activity disorders in preschool children predetermines the practicability of the development of a neurological correction individual trajectory and abilitional programs to reduce and minimize the manifestations of disorders in communicative and speech activity in children belonging to the group of biological and social risk.
ОСОБЛИВОСТІ ПРОФЕСІЙНОГО САМОВИЗНАЧЕННЯ ОСОБИСТОСТІ У РАННІЙ ЮНОСТІ (ГЕНДЕРНИЙ АСПЕКТ)
Authors: Бодашевська Ю. С.
Published: April 2020

The article describes gender peculiarities of making early career choices. The results of the empirical study of the peculiarities of the relationship between the gender identity and professional focus are presented. It is revealed that the choice of profession relates to gender identity. Differences were found between the image of the self-actualized woman and the image of the self- actualized circles. These differences relate to the intellectual sphere, social activity, ideas about ways. Thus, respondents with masculine identity tend to choose activities related to sign system and technology. Respondents with feminine and ambivalent identities most often choose activities related to people and nature.
ПОЛУЧЕНИЕ МОДИФИЦИРОВАННЫХ НИТРАМИНОВ ДЛЯ ПРИМЕНЕНИЯ В НЕЭЛЕКТРИЧЕСКИХ СИСТЕМАХ ИНИЦИИРОВАНИЯ
Authors: М. М. Челтонов  , С. А. Опарин  , Е. Ю. Нестерова  , А. Л. Кириченко  , Е. Б. Устименко
Published: April 2020

In present-day conditions of Ukraine the setup of domestic production of non-electric initiation systems (NEIS) is an important issue. The main component of NEIS consisting of mixture of nitramine (octogen or hexogen) and aluminum. The deficiency of the above nitramines may be solved through applying the resource-recovery technologies of disposal of solid propellant (SP) and ammunition, which are further unusable as intended. However, when applying the mentioned technologies, the nitramine extracted from solid propellant and ammunition does not conform to the requirements on quality of commercial product for NEIS production. The purpose of this research is to obtain nitramine extracted from solid propellants by crystallization in dimethyl sulphoxide (DMSO) aqueous solution to obtain a product usable in manufacturing NEIS shock tubes.
CLINICAL EXPERIENCE IN USING COMBINED FERROTHERAPY WITH L-CARNITINE IN STANDARD TREATMENT OF PATIENTS WITH CHRONIC HEART FAILURE WITH REDUCED LEFT VENTRICLE EJECTION FRACTION WITH CONCOMITANT IRON DEFICIENCY ANEMIA
Authors: Valeriy P Ivanov  , Mariіa O Kolesnyk  , Oleg N Kolesnуk
Published: April 2020

Chronic heart failure (CHF) is a global public health problem. Despite all the technical advances available in modern cardiology, a medical strategy for the treatment of CHF has been and remains the main focus of therapeutic intervention. А particular problem is the treatment of CHF with concomitant pathology. The modern pharmacological strategy for the treatment of patients with CHF and iron deficiency anemia, except iron preparations, must take into account the use of agents that have antihypoxic, antioxidant and membrane-stabilizing effects, and at the same time regulatory effect on the metabolism of physiologically active compounds to improve the condition of patients. Therefore, this study is aimed to evaluate the effectiveness of iron deficiency anemia’s correction, identify and compare the effect of oral ferrotherapy and combined use of ferrotherapy with L-carnitine on clinical and instrumental parameters of patients with chronic heart failure with reduced ejection fraction of left ventricle as possible variants of additional therapy to standard treatment.
ОСОБЛИВОСТІ ЛІКУВАННЯ ХВОРИХ НА ХРОНІЧНИЙ БЕЗКАМ’ЯНИЙ ХОЛЕЦИСТИТ ІЗ СУПУТНЬОЮ ГІПЕРТОНІЧНОЮ ХВОРОБОЮ З УРАХУВАННЯМ ПОРУШЕНЬ В СИСТЕМІ ГОМЕОСТАЗУ
Authors: Олена Карая
Published: April 2020

Recovery of chronic acalculous cholecystitis (CAC) in patients with hypetension disease (HD) is shown to be accompanied by inhibition of antioxidant system parameters and significant changes in lipid peroxidaton, which cause elevation of anti-inflammatiry cytokines level. The studied parameters correlate with thecharacterof the inflammatory processand the type of the gallbladder dyskinesia. The use of Choliver and Duspatalin in complex treatment of CAC in patients with HD provides clinical and laboratory remission, which allows to recommend these drugs for treatment of the above persons.
FINANCIAL SYSTEM DEVELOPMENT IN REPUBLIC OF MOLDOVA IN THE CONTEXT OF THE NEW INTERNATIONAL FINANCIAL ARCHITECTURE
Authors: Lopotenco Viorica
Published: April 2020

The primary purpose of this paper is to analyze the transformations in the international financial architecture and their impact on the national financial system. For this purpose, a multi-criteria analysis (matrix approach) is used, which represents a structured approach used to determine the general preferences between several alternative options, which lead to the achievement of several objectives. The approach of the matrix gives the possibility to combine the size of the set of the financial sector.The conclusions of this study consist in the fact that the complex resolution of the challenges in the international financial architecture implies the creation of foundations for the implementation of the progressive structural changes in the economy, capable of contributing to the sustainable economic development.
ІНТЕЛЕКТУАЛЬНІ РЕСУРСИ ДЕРЖАВНОГО УПРАВЛІННЯ: ОСОБЛИВОСТІ ВИКОРИСТАННЯ ТА ВІДТВОРЕННЯ
Authors: Марутян Рена
Published: April 2020

The article deals with the managing process of the formation, development and reproduction of national intellectual resources of public administration (IRPA), which includes their use and reproduction; their structure and their function characteristics are revealed; the author's definition of the concept of "national intellectual resource of public administration" is proposed; the importance of managing national intellectual resources of public administration for modern public-management practice is characterized. It is argued that the peculiarity of national IRPAs lies in their flexibility, in that the process of their formation takes place in a separate national- cultural space, which is influenced by historical, political, educational, information and other factors. It is proved that the management of the national IRPA is a process of purposeful influence on the components of the national IRPA, their interaction in order to secure the state's advantages in the modern world or to achieve its development goals. The factors that determine the need for the formation, development, use and reproduction of national IRPA s are revealed.
ГАСТРОЛІ ІТАЛІЙЦІВ В СУМАХ: ПОГЛЯД ЧЕРЕЗ СТО РОКІВ
Authors: Довжинець І. Г.
Published: April 2020

The article focuses upon analysis of tour performances of the Gonzalez brothers Italian opera company in provincial Ukrainian town Sumy in the beginning of the XX century. It is noted that musicians` coming was an event which was actively discussed in local press. Each performance had reviews of educative and at the same time critical character. The musical observer described vocal qualities of the artists, their technique, stage effect, orchestra sounding, emotional energy of the shows in details. Basing upon the analysis of these materials the level of touring Italian opera company, performing arts of its soloists and also an impression it produced on Sumy audience are found out. The conclusion enlightens the role of Italian opera company tour in cultural life of the chief town of a district and formation of its musical environment.
ПОГЛЯДИ ПЕДОЛОГІВ НА ПРИЧИНИ ПОЯВИ «МОРАЛЬНО ДЕФЕКТИВНИХ» ДІТЕЙ У ПУБЛІКАЦІЯХ В ПЕДАГОГІЧНИХ ЖУРНАЛАХ (20-30 рр. ХХ ст.)
Authors: Бондарець Марія
Published: April 2020

In the article based on the analysis of publications in pedagogical journals of the 20-30s of the XX century (“The Way of Education”, “The Way of Enlightenment”, “Pedology”, “Our School”) the views of well-known psychologists and educationists on the social causes of the emergence of “morally defective children” have been generalized.It has been found that the term “morally defective child” was used to refer to children who suffered from character and emotional-will disorders, and who were prone to aggressive and unlawful behavior or were pedagogically neglected, homeless, etc.The ambiguity of approaches to the interpretation of the causes of the emergence of “morally defective” children in the pedagogy and psychology of the studied period has been proved. In particular, A. Zalkind, L. Vygotskyi, O. Mukhina, M. Tarasevich in their works substantiated the role of the social environment as a factor of morally defective childhood.It has been proved the interconnection of moral deficiency with the socio- economic and cultural-pedagogical conditions of the development and upbringing of a child.
ПСИХОАНАЛИТИЧЕСКИЙ ТРЕНИНГ КАК ИНСТРУМЕНТ РАЗВИТИЯ ПСИХОЛОГИЧЕСКИХ ГРАНИЦ ПОДРОСТКА
Authors: Дорожкин В. Р.  , Савченко Е. В.
Published: April 2020

The article is devoted to psychoanalytic training as an instrument for the development of psychological boundaries of adolescents. The base principles of the training are described and the features of its structure and duration are characterized. The topics that were put forward as the main ones for certain meetings of teenage groups are justified in detail. Psychoanalytic training has been studied in terms of its effectiveness and impact on the development of the boundaries as well as their structure and functions in adolescents. The analysis is conducted of all those mental changes and new growths due to which the formation of the boundaries of the personality takes place.
РЕЛИГИЯ В ТВОРЧЕСТВЕ СУХРАБА СИПЕХРИ
Authors: Шоалиева Наргиза
Published: April 2020

Relation to religion and religious values in the poetry of Suhrab Sipehri, occupies a special place among the spiritual values of the poet. Being an inextricable part of Sipehri’s worldview, this attitude can be called the main idea of his creative heritage, which acts as a kind of harmony between the poet’s society, being and “I”. In particular, the concept of the essence of religion and being as the main means of expression is manifested to a greater or lesser extent in almost all verses of Suhrab Sipehri.According to Sipehri, religion and faith are a spiritual tool that can satisfy a person’s moral needs. It cannot be imposed or imposed on anyone by force. Faith should not come from outside, but from the person himself, from his moral and spiritual needs, otherwise it will not turn into a means of improving a person, or ennoblement of him, but as a means restricting human freedom.
Streptococcus intermedius Splenic Abscess in a Child: Case Report and Review of the Literature
Authors: Patel Niraj , Massengill D. , Patel Niraj
Published: April 2020

Objective: We report a case of Streptococcus intermedius splenic abscess and review of relevant literature.
Design: A retrospective report and review of the English literature concerning splenic abscess cause by
Streptococcus intermedius via PubMed was conducted.
Results: An 8-year-old boy, who presented with fever, abdominal pain, and vomiting, was found to have a
large splenic fluid collection. He underwent ultrasound-guided aspiration of the abscess, and the culture
grew Streptococcus intermedius. His symptoms and radiographic findings resolved after completion of
antibiotics. Isolated splenic abscesses are rare, and this represents the second case in the literature of splenic
abscess caused by Streptococcus intermedius.
Conclusion: Streptococcus intermedius is a rare cause of splenic abscess. Isolated splenic abscess requires
drainage for both diagnostic and therapeutic purposes.