bluuebunny/crossref_metadata_2025 huggingface dataset:
Lesión vulvar y perineal secundaria a trauma pelviperineal complejo: presentación de un caso y revisión de la literatura
Authors: Hernández-Tiria María Camila , Navarro-Devia Antonio José , Osorio-Ruiz Ana María
Published: January 2016

Objetivo: hacer una revisión de la literatura orientada a describir la anatomía quirúrgica, el diagnóstico y el manejo de las lesiones vulvares y perineales secundarias a trauma genital y perineal de alto impacto.

Materiales y métodos: se presenta el caso de una adolescente de 15 años de edad, que presentó fractura inestable de pelvis, desgarro rectal y trauma vulvar, con destrucción de la anatomía del piso pélvico, atendida en una clínica privada de referencia de la cuidad de Bogotá (Colombia). Se realizó reconstrucción del piso pélvico por parte del servicio de ginecología de forma inmediata y manejo conjunto de las otras lesiones con cirugía general y ortopedia. Se hizo una revisión de la literatura registrada con los siguientes términos MeSH: heridas y traumatismos, vulva, genitales femeninos, lesiones y ginecología, en las bases de datos Medline vía PubMed, desde el año 1940 hasta el 2015; además, en EBSCO y Lilacs se buscaron artículos de revisión y reportes de caso publicados en inglés y español.

Resultados: inicialmente se seleccionaron 20 estudios, de los cuales se descartaron 6 artículos en los que el principal objetivo era el manejo del trauma obstétrico, trauma por prolapso o trauma con mayor compromiso abdominal; quedaron 14 estudios. Tres de los casos reportados se describen en pacientes prepúberes, 9 en mujeres en edad reproductiva y 2 en posmenopáusicas por diferentes mecanismos de trauma. El diagnóstico se basa en la historia clínica y la exploración física. Las imágenes diagnósticas podrían ayudar a establecer la magnitud del daño pélvico. Se considera una emergencia quirúrgica; se debe hacer reparación de los músculos y nervios, y ligadura de vasos sangrantes, además de determinar la necesidad de derivación intestinal o urinaria.

Conclusión: el trauma vulvar es una urgencia quirúrgica por las consecuencias de funcionalidad del tracto genitourinario y riesgo de contaminación o pérdida de tejido. La intervención debe ser oportuna y el manejo multidisciplinario. El abordaje que se realice va a depender de los hallazgos encontrados en el momento de la valoración y de las condiciones médicas asociadas.
A RESPONSABILIDADE CIVIL DO EMPREGADOR PELOS DANOS NO MEIO AMBIENTE DO TRABALHO
Authors: Pozzetti Valmir Cesar , Schettini Mariana Cruz
Published: January 2016

O modelo capitalista e a livre iniciativa, vigentes no Brasil, têm trazido algumas sequelas aos trabalhadores, o que é preocupante, pois corremos o risco de, em um futuro próximo, termos um exército de inválidos, oriundos de nossos postos de trabalho. Assim, o objetivo desta pesquisa é analisar a responsabilidade civil do empregador, em virtude das doenças adquiridas no meio ambiente de trabalho; pois diante desta realidade preocupante, é possível, através da teoria do risco integral (responsabilidade objetiva), afastar a discussão sobre a culpa; porquanto a obrigação de indenizar dependerá somente da comprovação do evento danoso e do nexo causal. Assim, afasta-se as excludentes da responsabilidade, uma vez que o meio ambiente do trabalho envolve a vida do trabalhador, por isso é fundamental que seja equilibrado e que se assegurem condições dignas de trabalho. A metodologia utilizada nesta pesquisa é indutiva e qualitativa quanto aos fins e, quanto aos meios é bibliográfica.
A GESTÃO AMBIENTAL DAS TERRAS INDÍGENAS E DE SEUS RECURSOS NATURAIS: fundamentos jurídicos, limites e desafios.
Authors: Claudino de Brito Adam Luiz , Barbosa Erivaldo Moreira
Published: January 2016

Este artigo aborda as políticas ambientais indígenas e os processos de gestão dos recursos naturais nas terras indígenas, compreendidas como o espaço de vida e liberdade dos índios, sujeitas a um cenário crescente de degradação ambiental. Busca-se elucidar os sentidos jurídicos da Lei n. 12.593/2012 e Decreto n. 7.747/2012, por meio do método hermenêutico-normativo, de modo a verificar a finalidade social dessas normas que tratam da gestão ambiental da terra indígena. Registra-se alguns avanços em nível de criação e execução de ações voltadas para a gestão ambiental, etnodesenvolvimento, promoção da saúde, regularização fundiária e reconhecimento da cidadania, mobilização e participação social indígena. Todavia, o que se tem percebido é que um conjunto de fatores reforçam o processo de negação de direitos dos povos, o que justifica a criação de espaços de participação popular indígena para a formulação de políticas públicas democráticas nos processos decisórios envolvendo a gestão da terra indígena.
A PROTEÇÃO INTERNACIONAL AOS REFUGIADOS AMBIENTAIS A PARTIR DO CASO KIRIBATI
Authors: Grubba Leilane Serratine , Antonia Sofia Mafrica Chiara
Published: January 2016

Existe uma grande preocupação do Direito Internacional com a categoria dos refugiados, preocupação essa que ganhou força no pós-segunda Guerra Mundial. Contudo, parece que a categoria dos refugiados, que prevê direitos aos refugiados em razão de perseguições por motivos de nacionalidade, raça, grupo social, grupo religioso ou opinião política, não engloba as pessoas vitimadas por catástrofes ambientais. Existe um limbo conceitual no que se refere ao refúgio ambiental. Diante disso, o artigo tem por objeto os refugiados ambientais e busca analisar, por meio do método dedutivo, se há possibilidade de aceitação dos refugiados ambientais pelo Direito Internacional. Para cumprir com o objetivo proposto, o artigo problematizará a existência dos refugiados ambientais tendo como ponto de partida o caso da República Independente do Kiribati e a necessidade do reconhecimento do estatuto de refugiados aos seus habitantes, em decorrência de causas ambientais. A análise será realizada a partir dos instrumentos de refugiados presentes no Direito Internacional. Para este artigo, considerou-se que parece fundamental compreender que o Direito Internacional deve enfrentar o desafio dos refugiados ambientais e apresentar uma adequada solução que possibilite garantir a proteção da dignidade dessas pessoas.
BASES JURÍDICAS PARA EL USO DE INSTRUMENTOS ECONÓMICOS EN LAS POLÍTICAS AMBIENTALES MUNICIPALES EN MÉXICO
Authors: López Tania García
Published: January 2016

En el presente trabajo se presentan las bases jurídicas para la utilización de instrumentos económicos en material ambiental en el municipio en México. Se analiza el marco jurídico para cada uno de estos instrumentos (fiscales, financieros y de mercado) y los ámbitos de acción en material ambiental a nivel municipal.
Root Coverage Procedure With Connective Tissue Graft Harvested From a Distal Wedge: A Case Report
Authors: Wang Chin‐Wei , Li Chia‐Cheng , Krawczyk Walter , Kim David M.
Published: January 2016

Introduction: This case report illustrates the use of a connective tissue (CT) graft harvested from a distal wedge procedure for root coverage. The retromolar area could be an alternative donor site, especially when a distal wedge procedure is planned. This approach offers an alternative CT donor site for the treatment of a localized gingival recession (GR).

Case Presentation: A healthy 22‐year‐old female patient presented with a localized Miller Class II GR defect on a mandibular incisor (tooth #25) caused by trauma from a lip piercing. Probing depths of 6 mm were also noted bilaterally over the distal aspect of the mandibular second molars. A root coverage procedure was performed, together with a distal wedge procedure for pseudopocket reduction. A CT graft harvested from a distal wedge was used for the root coverage. Complete root coverage with stable follow‐up was documented up to 2 years, 5 months. Tissue from a contralateral distal wedge was submitted for histologic evaluation. Histopathologic examination showed dense collagenous fibrous tissue with no inflammatory infiltrates.

Conclusions: Localized GR can be treated with a CT graft harvested from a distal wedge without significant inflammation. The mandibular retromolar area may serve as an alternative viable donor site in selected cases.
Processo de Produção de Cerveja
Authors: D. Junior Amaro A. , Vieira Antonia G. , Ferreira Taciano P.
Published: January 2016

A cerveja é uma bebida alcoólica não destilada, obtida da fermentação alcoólica do mosto de cereal maltado, geralmente malte de cevada. O presente trabalho apresenta as etapas da produção de cerveja, mostrando as matérias-primas que são utilizadas durante o processamento, as quais passam pela fabricação do mosto, fermentação, maturação, filtração e engarrafamento. Este material possibilita uma introdução ao conhecimento de indústria de produção de cerveja, fazendo um apanhado geral das etapas do processo produtivo.
Profile of brazilian dental students and its relationship to anxiety levels
Authors: Silva Nayane Cavalcante Ferreira da , Silva Bruno Rocha da , Vasconcelos Hélvia Menezes , Oliveira Patrícia Maria Costa de , Teixeira Edson Holanda , Aguiar Andréa Silvia Walter de
Published: January 2016

The aim of this study was to evaluate the profile of dental students and its relationship to anxiety levels. The State-Trait Anxiety Inventory was applied to 207 first- to fifth-year undergraduates enrolled in the dentistry program at the School of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Brazil. Participants were aged 17 to 29 years, and the maiority were women (57.5%). Students had a weekly workload of up to 40 hours and performed at least two complementary activities, in addition to their undergraduate training. Almost all students (95.7%) had attended private high schools and 80.6% lived with their parents or spouses. Regarding parental education, 59.4% of mothers and 55.6% of fathers had a higher education degree. Most students showed medium levels of anxiety according to measurements of state anxiety (53.1%) and trait anxiety (81.6%). It can be concluded that more than 50% of students in the Dentistry graduation course of the Federal University of Ceará showed an average level of anxiety, and that the excessive workload and enrichment activities necessary to obtain the undergraduate degree in Dentistry probably can be influencing the anxiety levels of students, however, more studies and statistical tests should be performed to identify the root causes in order to preserve the mental health of these future dentists.
Ocorrência de dor em bebês internados em unidade de terapia intensiva neonatal de maternidade terciária
Authors: Nazareth Caroline Diniz , Lavor Maria Francielze Holanda , Sousa Tânia Maria Araújo Santos
Published: January 2016

Introdução: Por muitos anos, acreditou-se que os recém-nascidos (RNs) eram incapazes de sentir dor, devido ao pressuposto que seu sistema nervoso ainda não estaria completamente formado. Os RNs podem perceber a dor com mais intensidade do que as crianças e os adultos, devido aos seus mecanismos de controle inibitório imaturos, diminuindo capacidade de modular a experiência dolorosa.  Objetivos: Identificar a ocorrência de dor em bebês internados e mensurar a utilização de analgesia farmacológica. Material e Métodos: Estudo transversal prospectivo, realizado nas Unidades de Terapia Intensiva Neonatal de um hospital terciário, no período de novembro de 2014 a fevereiro de 2015. Resultados: Dor foi identificada em 36% dos pacientes. Cinco (10%) pacientes receberam medidas farmacológicas de analgesia. Conclusão: Houve discrepância entre a frequência de dor encontrada e a de utilização de medidas para aliviá-la. Mostra-se necessária a implantação de um protocolo de avaliação e terapêutica de dor pela Instituição.
Restrição de crescimento seletiva em gestação gemelar monocriônica: relato de caso
Authors: Lima Filho Pedro Wilson Leitão , Feitosa Francisco Edson de Lucena , Feitosa Helvécio Neves , Carvalho Neto Raimundo Homero de , Carvalho Francisco Herlânio Costa
Published: January 2016

A restrição de crescimento fetal (RCF) ocorre em aproximadamente 3 a 10% das gestações únicas, em 9,1% de todos os gêmeos, e em 9,9% dos gêmeos monocoriônicos. O déficit de crescimento pode comprometer apenas um dos gêmeos de forma seletiva (RCF-S). A morte espontânea do gêmeo com restrição pode resultar em morte concomitante ou deficiência neurológica grave do outro gêmeo.Há classificação em três subtipos para essa entidade clínica, onde os de tipo I (Doppler normal) são conduzidos de forma expectante com avaliação periódica ao Doppler. Para os subtipos II (Doppler anormal mantido) e os subtipos III (Doppler anormal intermitente) não há consenso na literatura, com tendência a realização do laser para separação das circulações com o intuito de evitar as conseqüências adversas decorrentes da morte potencial do gêmeo com RCFs.O objetivo deste relato de caso é apresentar uma evolução de RCFs Tipo I conduzida de forma conservadora com resultado satisfatório e discutir os aspectos desta importante entidade na obstetrícia.
Taste sensibility to phenylthiocarbamide and its relationship to food preferences
Authors: Pandolfi Marcela Maria , Chow Charles Yea Zen , Higashi Luciana Sayumi Fugimoto , Fonseca Ana Thamilla , Cunha Myllena De Andrade , França Carolina Nunes , Colombo-Souza Patrícia
Published: January 2016

Introduction: Foods like cabbage, broccoli, pepper and wine, containing proteins such as phenylthiocarbamide (PTC), cause a bitter taste in some people. Studies showed the relation between tasting profile and the development of obesity, and consequently leading to cardiovascular disease. Objective: Compare the differences in the taste sensibility to PTC present in some foods in individuals classified according to the nutritional status. Methods: One hundred fifty-three patients classified as eutrophic, overweight or obese received one drop of each PTC solution in the tongue, since the most diluted to the individual perception to bitter taste, in a total of 15 increasing grades. Results: Participants were predominantly middle-aged females, eutrophics and supertasters. It was found a correlation between PTC solution and red wine in the three groups evaluated (eutrophic, obese and overweight). Besides, eutrophic and obese that disliked wine had more sensibility to PTC. Conclusion: Our main finding showed that eutrophic and obese that disliked red wine had more sensibility to PTC. We did not find differences in the sensitivity to PTC for the other foods analyzed (fried foods, fruit and vegetables).
Perfil do uso de agentes biológicos no tratamento da artrite reumatoide: experiência do Hospital Universitário Walter Cantídio
Authors: Lima Raquel Telles Quixadá , Bezerra Mailze Campos , Ribeiro Ádilla Thaysa Mendes , Medeiros Marta Maria Das Chagas
Published: January 2016

O tratamento da artrite reumatoide (AR) visa prevenir dano articular irreversível e inclui o uso de drogas sintéticas e biológicas. O objetivo deste estudo foi avaliar o perfil do uso de imunobiológicos na artrite reumatoide, no serviço de reumatologia do HUWC. Este estudo observacional, retrospectivo e transversal, identificou 131 pacientes com AR, em uso atual ou nos últimos 5 anos de agentes biológicos. Foram coletados, em entrevista e revisão de prontuário, dados demográficos, clínicos e terapêuticos, incluindo a presença de eventos adversos e infecções relacionadas às drogas prescritas. Nossa amostra se constituiu de subgrupo de pacientes com doença grave e baixo nível socioeconômico. Os imunobiológicos mais utilizados foram os anti-TNF. Cerca de metade dos pacientes apresentou screening positivo para TB latente. O perfil de uso dos agentes biológicos no tratamento dos pacientes com diagnóstico de AR encontra-se em concordância com as recomendações clínicas vigentes.
Staphylococcus aureus (MRSA and CA-MRSA strains) in South America: comparative review to emergence of strains in North America and worldwide
Authors: Farias Andre Leonardo Nogueira , Frota Cristiane Cunha
Published: January 2016

Background: In the last few years, 3 different strains of MRSA have emerged: Community-associated Methicillin-resistant S. aureus (CA-MRSA), Hospital-associated (HA-MRSA), and Livestock-associated (LA-MRSA). The most common CA-MRSA strain is USA 300 lineage. In Brasil, this superbacteria is an important public health problem, once they are associated with severe infections (sepsis, shock and osteomyelitis), high mortality rates (including babies) and low response to usual treatments. Aim: To review attempts to compare CA-MRSA strains in South America and propose an interconnection with patterns of North America and worldwide strains. Methods: Non-systematic review. Findings: Epidemiological and Genotyping definitions were used to compare different strains in different continents. Thus, we could determine ST30+ as the most common lineage in the Brazil and South America, USA 300 lineage as the most common in North America and ST80+ as the most common in Europe. Conclusion: MRSA is a seriously public health problem in Brazil and worldwide.  In few years scientist will need a better understand of bacteria-derived factors that participate in enhanced MRSA pathogenesis & host susceptibility. Also, scientists will need to improve tools for an early diagnosis and they will need to enhance preventative/therapeutic modalities. However, new challenges will keep emerging.
Linha de cuidados em obesidade: protocolo de atenção especializada integral à obesidade e síndrome metabólica do Hospital Universitário Walter Cantídio (UFC)
Authors: Junqueira Ana Flávia Torquato de Araújo , Fernandes Virginia Oliveira , Recamonde Joseline Maria Alves Gomes , Brito Nara Fábula Costa de , Lima Virgínia Serpa Correia , Alexandre Solange Gurgel , Lopes Synara Cavalcante , Montenegro Junior Renan Magalhães
Published: January 2016

A obesidade é um sério problema de saúde mundial, responsável pelo aumento na incidência de diversas outras doenças, aumento da mortalidade total, e elevação dos custos com saúde. No Brasil, onde as doenças crônicas não comunicáveis dominam o ranking de mortalidade, mais da metade da população está acima do peso. Nesse contexto, o Ministério da Saúde estabeleceu a criação das Linhas de Cuidados direcionadas às doenças crônicas de maior impacto epidemiológico. As linhas de cuidado tem como objetivo coordenar os fluxos assistenciais que devem ser garantidos ao usuário, no sentido de atender às suas necessidades de saúde de maneira integral, e reduzir a fragmentação de serviços do Sistema Único de Saúde (SUS).  Este documento propõe diretrizes clínicas para a organização de uma linha de cuidados em obesidade na rede pública de Fortaleza, onde o serviço especializado e multiprofissional será oferecido no Hospital Universitário Walter Cantídio.
Simple parametrization methods for generating Adomian polynomials
Authors: Kataria K.K. , Vellaisamy P.
Published: January 2016

In this paper, we discuss two simple parametrization methods for calculating
Adomian polynomials for several nonlinear operators, which utilize the
orthogonality of functions einx, where n is an integer. Some important
properties of Adomian polynomials are also discussed and illustrated with
examples. These methods require minimum computation, are easy to implement,
and are extended to multivariable case also. Examples of different forms of
nonlinearity, which includes the one involved in the Navier Stokes equation,
is considered. Explicit expression for the n-th order Adomian polynomials are
obtained in most of the examples.
Hegel’s logic as the exposition of god from the end of the world
Authors: Simoniti Jure
Published: January 2016

The article attempts to reconstruct the logical space within which, at the
beginning of Hegel?s Logic, ?being? and ?nothing? are entitled to emerge and
receive their names. In German Idealism, the concept of ?being? is linked to
the form of a proposition; Fichte grounds a new truth-value on the absolute
thesis of the ?thetical judgement?. And the article?s first thesis claims
that Hegel couldn?t have placed ?being? at the beginning of this great
system, if the ground of its logical space had not been laid out by precisely
those shifts of German Idealism that posited the ontological function of the
judgement. At the same time, the abstract negation, the absence of a relation
and sufficient reason between ?being? and ?nothing?, reveals a structure of
an irreducibly dual beginning. The logical background of this original
duality could be constituted by the invention of the ?transcendental
inter-subjectivity? in German Idealism, manifested, for instance, in Hegel?s
life-and-death struggle of two self-consciousnesses. The second thesis
therefore suggests that ?being? and ?nothing? are elements of the logical
space, established in concreto in a social situation of (at least) two
subjects one of whom poses an affirmative statement and the other negates it
abstractly. From here, one could draw out the coordinates of a sphere by the
name of ?public? whose structure is defined by the invalidation of two basic
laws of thought, the law of non-contradiction and the principle of sufficient
reason. The article shows how only the statements capable of absorbing
negation, of sustaining a co-existence of affirmation and its symmetrical,
abstract negation, can climb the ladder of public perceptibility and social
impact.
The owl of Minerva from dusk till dawn, or, two shades of gray
Authors: Dolar Mladen
Published: January 2016

The paper takes as its starting point the figure of the owl as the emblem of
philosophy, it looks at its history and takes up its most significant
philosophical use, the notorious passage where Hegel uses the owl as the
indication of philosophy?s necessary belatedness. This is the passage which
is usually taken as the point of indictment of Hegel?s position and the role
he ascribed to philosophy. Hegel?s adage ?What is rational is actual, and
what is actual is rational? is scrutinized in its various aspects,
particularly in view of its other version, ?what is rational must happen?.
The tension between the ?is? and the ?ought? is perhaps the clue to
understanding this adage, where Hegel doesn?t opt for the one or the other,
but aims at the paradoxical intersection of the two. Hegel?s adage is put in
contrast with Marx?s Thesis Eleven. The paper considers the concepts of the
rational, the actual, the belatedness/retroaction, the grayness and finally
the owl (and the part that bestiary plays in philosophy), thus trying to
circumscribe the task that should be assigned to philosophy.
Science and philosophy in Deleuze
Authors: Krtolica Igor
Published: January 2016

Deleuze will not wait until he had completed his works to frame and formulate
a theory on the relation between philosophy and science. The first
articulations of this question are already present as early as the 1950s and
1960s in the studies on Bergson and Nietzsche, and then in Difference and
repetition as well as in The Logic of Sense. It is also true that this
question will be specifically developed in 1991 in What Is Philosophy? But
throughout his work, the main thrust would proceed. This issue, it seems,
comprises three main aspects: in the first place, in a polemic against the
neo-Kantian epistemological legacy, it primarily consists in denying the
critical definition of philosophy as being a ?reflection on scientific
knowledge? to replace it by a conception drawn from Bergson?s expressionist
ontology that places science and philosophy on both sides of the being;
secondly, in an attempt to restore the concept of dialectics, it consists in
making the dialectics of ideas the communal sphere of both science and
philosophy; thirdly, aiming to specify every form of thinking, it consists in
shaping how each expresses its ideas or its problems with its own signs.
These three aspects, it seems, can frame the overall conception Deleuze
formed of the link between science and philosophy. We shall successively
analyze them, exclusively considering the first period of Deleuze?s work,
which is to say the pre-guattarian publications.
Identification of microsatellite markers linked to thermotolerance in silkworm by bulk segregant analysis and in silico mapping
Authors: Chandrakanth N. , Moorthy S.M. , Ponnuvel K.M. , Sivaprasad V.
Published: January 2016

Silkworm, being a poikilothermic insect, its growth and development is
affected by environmental factors especially, temperature. In tropical
countries like India, it has considerable effect on silk production due to
the prevailing of hot climatic conditions. Previous attempts to evolve
silkworm breeds and hybrids tolerant to high temperature by traditional
breeding methods have not yielded the desired results. Hence application of
new strategies like marker assisted selection (MAS) could be the most
effective strategy for developing a thermo-tolerant bivoltine silkworm for
sustainable silk production in India. As a prelude, in this study it is aimed
to identify simple sequence repeat (SSR) markers closely linked with
thermotolerance in silkworm. To do so, 20 silkworm breeds were evaluated at
high temperature (36?C) and based on pupation percentage, two multivoltines
(Nistari and Cambodge) and two bivoltines (SK4C and BHR3) were identified as
thermo-tolerant and one bivoltine (CSR2) was identified as the susceptible
breed. These breeds were screened with 85 SSR markers drawn from different
linkage groups and out of those, only 11 markers (12.9%) showed distinct
polymorphism between thermo-tolerant and susceptible breeds. Further, bulked
segregant analysis (BSA) was performed using 11 polymorphic SSR primers, by
comparing the SSR profiles of the tolerant (Nistari) and susceptible (CSR2)
parents, their F1 and F2 bulks. Nevertheless, only 5 markers generated clear
differences in the amplified DNAs between the bulks corresponding to that of
the parents suggesting that the DNA regions amplified by these SSR markers
are closely linked to thermotolerance in B. mori. The results obtained
through bulk segregant analysis was further confirmed by genotyping 5 linked
SSR markers using 140 individual F2 progenies. Of these 5 markers, highest
Spearman's rho correlation coefficient was shown by S0816 indicating a high
degree of closeness between the genotypic and phenotype variations in F2
population. Furthermore, we have also attempted to locate the genes near to
S0816 by in silico approach and upshot revealed 3 genes nearer to its
sequence on the B. mori genome. The BGIBMGA005249 gene was found to be
located nearest to S0816 at a distance of 14.8 Kb. But, further studies are
required in this regard to derive a relationship between the thermotolerance
and the functional role of identified genes nearer to the closest marker, so
that the identified markers can be used to develop a thermo-tolerant silkworm
breed through MAS.
Influence of tomato genotype to phenolic compounds content and antioxidant activity as reaction to early blight
Authors: Medic-Pap Sladjana , Prvulovic Dejan , Takac Ana , Vlajic Slobodan , Danojevic Dario , Takac Adam , Masirevic Stevan
Published: January 2016

Early blight is one of the most common and destructive tomato disease and it
is caused by the fungus Alternaria solani. The aim of this paper was to
screen the reaction of ten tomato genotypes (collection of the Institute of
Field and Vegetable Crops) against natural infection of early blight. Tested
genotypes showed significant differences in the disease occurrence on leaves
but not on fruits. However, at the biochemical level, total phenolics (TP),
tannins (TT), flavonoids (TF) and antioxidant activity in tomato fruits was
significantly affected by genotype, disease occurrence and interaction of
these two factors. According to obtained results, content of these secondary
metabolites could be used as a one of the parameters in the evaluation of
tomato resistance to EB.
Agrobacterium-mediated transformation of ornamental species: A review
Authors: Milosevic Snezana , Cingel Aleksandar , Subotic Angelina
Published: January 2016

Integration of desirable traits into commercial ornamentals using genetic
engineering techniques is a powerful tool in contemporary biotechnology.
However, these techniques have had a limited impact in the domain of
ornamental horticulture, particularly floriculture. Modifications of the
color, architecture or fragrance of the flowers as well as an improvement of
the plant tolerance/resistance against abiotic and biotic stresses using
plant transformation techniques, is still in its infancy. This review focuses
on the application of Agrobacterium-mediated transformation, a major plant
genetic engineering approach to ornamental plant breeding and the impact it
has had to date.
Non-parametric stability analyses of protein content in multi-environment trials of wheat (T. aestivum L.)
Authors: Kaya Yuksel , Sahin Mehmet
Published: January 2016

According to literature, a detailed paper has not been published yet on using
non-parametric stability statistics for evaluating genotypic stability in
protein content (PC) of wheat. Thus, this study aimed to investigate the
stability for PC of wheat using sixteen non-parametric stability measures
(YSD-PC standard deviation, RM-Rank mean, RSD-Rank?s standard deviation,
RS-Rank Sum stability statistic, PA-Percentage of adaptability, R1 and
R2-Range indexes, TOP-Ranking, Si(1), Si(2), Si(3), Si(6), NPi(1), NPi(2)
NPi(3)and NPi(4) rank statistics, together with Y-PC mean). The study
included 13 wheat genotypes, consisting of 5 registered cultivars and 8
breeding lines, selected from National Wheat Breeding Program of Turkey. The
genotypes were grown in ten rain-fed environments, representative of major
rain-fed wheat-growing areas of Turkey, during 2011-2013 cropping seasons.
The ANOVA showed that the effects due to environments (E), genotypes (G) and
GE interaction (GEI) were significant (P < 0.01). Spearman?s rank correlation
and principal component analyses (PCA) also revealed that two types of
associations were found between the stability parameters: the first type
included Si(1), Si(2), Si(3), Si(6), NPi(1), NPi(2) NPi(3), NPi(4), RSD and
YSD parameters which were related to static stability, whereas the second
type consisted of the Y, RM, TOP, PA, RS, R1 and R2 parameters which are
related to dynamic concept of stability. Among the 8 breeding lines, G7 and
G8 were the best genotypes in terms of both high PC and stability. In
conclusion it could be suggested that dynamic non-parametric stability
statistics should be used for selecting genotypes with high PC and stable
when tested across a wide range of environments.
Fetal ultrasound findings in trisomy 18 at midpregnancy
Authors: Petrovic Bojana , Ljubic Aleksandar , Komnenic Milica , Joksimovic Violeta , Lekic-Miladinovic Olivera
Published: January 2016

Trisomy 18 (Edwards' syndrome), a lethal chromosomal aberration, is the
second most common autosomal trisomy with an incidence 1: 8000. The aim of
this study is to evaluate the sonographic findings in fetuses with trisomy
18. In ten years period (2002-2012) we analyzed fetal blood samples for
chromosome abnormalities. Samples were taken by cordocentesis and processed
using standard techniques. Sixteen metaphase cells were analyzed for
chromosomal constitution in each sample after tripsin-Giemsa banding. A
retrospective review of the cytogenetic laboratory database identified all
cases of trisomy 18 in ten years period. The prenatal sonographic studies in
fetuses at 16 to 22 weeks' gestation, done before invasive testing for the
karyotype were reviewed for anatomic findings. From 2100 samples of fetal
blood analyzed for chromosomal abnormalities, there were 16 (0,8%) with
complete trisomy 18. We found no mosaicism, or partial trisomy 18. The women
that carried fetuses with trisomy 18 were 17 to 42 years of age. Four of them
were above 35. From 16 fetuses with trisomy 18, 14 (87,5%) had some anomaly
detected by ultrasound, and other two were tested because of advanced
maternal age. The most common findings in trisomy 18 were intrauterine growth
retardation, polyhidramnios and anomalies of central nervous system, in 29%
respectively. Multiple anomalies, including central nervous system, hart and
gastrointestinal system anomalies, were also frequent (21%). Therapeutic
termination of pregnancy was done in all cases after genetic counseling.
Screening for chromosomal abnormalities using ultrasound is at utmost
importance in cases of nonhereditary aberrations. Detailed ultrasonographic
examinations of fetuses will enable health care providers to form the
appropriate management plan for each patient.
Segmentation and abnormality detection of cervical cancer cells using fast elm with particle swarm optimization
Authors: Sukumar P. , Gnanamurthy R.K.
Published: January 2016

Cervical cancer arises when the anomalous cells on the cervix mature
unmanageable obviously in the renovation sector. The most probably used
methods to detect abnormal cervical cells are the routine and there is no
difference between the abnormal and normal nuclei. So that the abnormal
nuclei found are brown in color while normal nuclei are blue in color. The
spread or cells are examined and the image denoising is performed based on
the Iterative Decision Based Algorithm. Image Segmentation is the method of
paneling a digital image into compound sections. The major utilize of
segmentation is to abridge or modify the demonstration of an image. The
images are segmented by applying anisotropic diffusion on the Denoised image.
Image can be enhanced using dark stretching to increase the quality of the
image. It separates the cells into all nuclei region and abnormal nuclei
region. The abnormal nuclei regions are further classified into touching and
non-touching regions and touching regions undergoes feature selection
process. The existing Support Vector Machines (SVM) is classified few nuclei
regions but the time to taken for execution is high. The abnormality detected
from the image is calculated as 45% from the total abnormal nuclei. Thus the
proposed method of Fast Particle Swarm Optimization with Extreme Learning
Machines (Fast PSO-ELM) to classify all nuclei regions further into touching
region and separated region. The iterative method for to training the ELM and
make it more efficient than the SVM method. In experimental result, the
proposed method of Fast PSO-ELM may shows the accuracy as above 90% and
execution time is calculated based on the abnormality (ratio of abnormal
nuclei regions to all nuclei regions) image. Therefore, Fast PSO-ELM helps to
detect the cervical cancer cells with maximum accuracy.
Mitochondrial coi in phylogenetic relationships of Laimaphelenchus belgradiensis (nematoda: Aphelenchoididae)
Authors: Oro Violeta , Milovanovic Nenad , Petrovic Violeta , Nikolic Bogdan , Blagojevic Jovana
Published: January 2016

Nematodes of the genus Laimaphelenchus are small and tiny organisms. Some
parts of their body are measured in nanometers. The identification and
classification of such organisms is a complex task. Previously, the major
source of classification was morphology based on anatomical characters and
measurements. Nowadays, this approach is supplemented by: ?nano-morphology?
based on scanning electron microscopy and molecular data and phylogeny,
resulting in molecular systematics. Laimaphelenchus belgradiensis was
recently described species. Since cytochrome c oxidase subunit I gene was
successful in DNA based species diagnosis, it was chosen as a molecular
marker to infer phylogeny of the newly discovered species. Phylogenetic
relationships were based on Bayesian inference, the pairwise distances and
the content of nitrogenous bases. The great genetic diversity was observed
among close and distant species.
Cytogenetic abnormalities in lymphocytes evaluated with micronucleus assay in medical personnel occupationally exposed to ionizing radiation
Authors: Velickova Nevenka , Milev Misko , Ruskovska Tatjana , Petrova Biljana , Nedeljkovik Bojana , Gorgieva Pale
Published: January 2016

The aim of this study was to evaluate the genotoxicity of ionizing radiation
on medical personnel using the micronucleus assay and to determine the human
health risk. Paired Student?s t-test shows significant statistical difference
between the total number of binucleated (BN) cells with micronuclei within
the two groups (exposed and control) (t=6,812; p<0,05). The mean of MN
frequencies in the exposed group increased in comparison with the mean of MN
frequencies in the control group. The formation of small and large
micronuclei indicates that medical personnel who are exposed on radiation in
their work place, have a chromosomal instability and a risk of cancer.
Spray freeze granulation of submicron alumina and its sintering behavior via spark plasma sintering
Authors: Liu Wei , Xie Zhipeng
Published: January 2016

Spray freeze granulation is an improved method based on spray granulation,
solving many limitations of spray granulation. In this work, spray freeze
granulation of submicron alumina is performed to explore the possibility of
industrial-scale production of dense alumina via spark plasma sintering.
Powder pretreatment such as sedimentation and the selection of granules with
the appropriate size are employed for the maximum use of the high qualified
as-prepared granules and granule sliding, which would provide a guidance for
the industrial-scale production. Debound granules were densified via SPS and
the corresponding sintering behaviors such as the recorded shrinkage and
shrinkage rate were discussed. The comparison of sintering behaviors between
granulated and as-received powder are conducted to identify the role of spray
freeze granulation in sinterability for dense alumina. The Vickers hardness
(Hv) and the fracture toughness (KIC) of the freeze granulated body are
higher than the corresponding properties of the as-received body due to the
more homogenous microstructure with little agglomeration in the particle
packing after freeze granulation.
Young’s modulus evaluation and thermal shock behavior of a porous SiC/cordierite composite material
Authors: Posarac-Markovic M. , Majstorovic J. , Devecerski A. , Matovic B. , Volkov-Husovic T.
Published: January 2016

Porous SiC/Cordierite Composite Material with graphite content (10%) was
synthesized. Evaluation of Young modulus of elasticity and thermal shock
behavior of these samples was presented. Thermal shock behavior was monitored
using water quench test, and non destructive methods such are UPVT and image
analysis were also used for accompaniment the level of destruction of the
samples during water quench test. Based on the level of destruction graphical
modeling of critical number of cycles was given. This approach was
implemented on discussion of the influence of the graphite content on thermal
stability behavior of the samples.
Fabrication and mechanical properties of Al2O3/TiAl in situ composites doped with Nb2O5
Authors: Wang F. , Fan N. , Zhu J. , Jiang H.
Published: January 2016

Al2O3/TiAl composites were successfully fabricated from powder mixtures of
Ti, Al, TiO2, Cr2O3 and Nb2O5 by a hot-press-assisted exothermic dispersion
method. The effect of the Cr2O3 and Nb2O5 addition on the microstructures and
mechanical properties of Al2O3/TiAl composites was characterized. The results
showed that the specimens are mainly composed of TiAl, Ti3Al, Al2O3, NbAl3
and Cr2Al. The Vicker-hardness and density of Al2O3/TiAl composites increase
gradually with the increase of Nb2O5 content. When the Nb2O5 content was 6.54
wt %, the flexural strength and fracture toughness of the composites have a
maximum values of 789.79 MPa and 9.69 MPa?m1/2, respectively. The improvement
of mechanical properties is discussed in detail.
Kinetics of reaction of roasting of soda ash and ilmenite ore concentrate for formation of sodium titanates
Authors: Nafeaa I.A. , Zekry A.F. , Khalifa M.G. , Farag A.B. , El-Hussiny N.A. , Shalabi M.E.H.
Published: January 2016

Alkaline metals and hydrogen titanates are of great interest for possible
applications. The soda ash and Rosetta ilmenite ore concentrate briquette
were investigated. The kinetic of formation of sodium titanate was studied in
the temperature range 700?C to 900?C.
Investigation of Campylobacter jejuni and Campylobacter coli isolated from broilers susceptibility to antibiotics
Authors: Tambur Zoran , Vukovic Branislava , Doder Radoje
Published: January 2016

In this work sensitivity to eritromycine, tetracycline and ciprofloxacin was
investigated on 16 (sixteen) strains Campylobacter jejuni and Campylobacter
coli originated from broilers? coecum by use of dics-diffussion method and
E-test. Out of 10 (ten) examined strains of C. jejuni, 1 strain (10%) was
resistant to erithromycin, 5 (five) examined strains (50%) to tetracycline
and 4 (four) examined strains (40%) to ciprofloxacine. Out of 6 investigated
strains of C. coli, 1 strain was resistant to erithromycin (16,7%), 5 of
investigated strains to tetracycline and ciprofloxacine (83,3%) (table 1 and
2, graph 3). Out of 16 (sixteen) investigated strains of C. jejuni and C.
coli, 9 (nine) strains were resistant to ciprofloxacine (56,2%), 2 (two)
strains to erythromycine (12,5%) and 10 of investigated strains to
tetracycline (62,5%).
Retrospective analysis of clinical and laboratory findings in hunting dogs with serologic reactions to tick-borne pathogens (Anaplasma phagocytophilum, Borrelia burgdorferi, Babesia canis, Ehrlichia canis, Ricketsia conorii)
Authors: Spasojevic-Kosic Ljubica , Savic Sara , Potkonjak Aleksandar , Vracar Vuk
Published: January 2016

Seroprevalence of tick-borne infections in endemic areas could be high. In
this study, we investigated the seroprevalence of tick-borne pathogens
(Anaplasma phagocytophilum, Borrelia burgdorferi, Babesia canis, Ehrlichia
canis, Rickettsia conorii) in hunting dogs, naturally infected with one or
more pathogens. Serological test results of the investigated animals were
compared to those from clinical examination, as well as from haematological
and biochemical analyses. A total of 74.14% dogs were seropositive (R.conorii
44.83%, B. canis 32.76%, B. burgdorferi 25.86%, E. canis 13.79%, A.
phagocytophilum 8.47%), with 25.86% of dogs seropositive to two pathogens,
15.52% seropositive to three pathogens, and 1.72% of dogs seropositive to
four pathogens. Among all registered clinical signs, only pyrexia (p<0.05)
and arrhythmia (p<0.05) were significant in seropositive dogs. There was no
significant difference between seropositive and seronegative dogs regarding
the majority of haematological and biochemical parameters. Statistically
significant difference was registered for particular haematological (number
of red blood cells and seroreactivity to B. burgdorferi) and biochemical
parameters (albumin concentration and seroreactivity to E. canis, and AST and
seroreactivity to R. conorii) but these values were not clinically
significant. The high exposure to tick-borne pathogens suggests that
ectoparasitic profilactic treatment is not adequate in examined population of
hunting dogs. Clinical finding of pyrexia need to be further investigated and
explained etiologically, which means that molecular diagnosis should be used
in order to identify larger number of pathogens because of the possibility of
coinfection.
Pathohistological and immunohistochemical parameters significant for prognosis and therapy of tumours in cats and dogs
Authors: Aleksic-Kovacevic Sanja , Vucicevic Ivana , Anicic Milan
Published: January 2016

The development of tumours implies a disproportion between proliferation,
growth and differentiation, which is accompanied by significant genotypic and
phenotypic variations in the diseased. The scenario of multiple oncogenic
effects on the inhibition of cell growth, apoptosis and maturation, on the
stimulation of proliferation, on cell migration and tissue invasion, is
responsible for the occurrence of tumours both in humans and in animals. The
qualitative and quantitative determination of biological prognostic factors
in the tissue of affected cats and dogs directly indicates a possible tumour
metastasizing, and consequently also the prognosis of neoplastic disease.
Monitoring of clinical and biological prognostic factors is important for
therapy and prediction of tumours in humans and animals. The determination of
the proliferative potential of tumour cells by immunohistochemical detection
of Ki-67 and PCNA is used in grading certain tumours in cats and dogs. It is
also possible immunohistochemically to prove factors of angiogenesis and
numerous activating and inhibiting proteins in the tumour tissue. In addition
to other histological, clinical and biological parameters, they are
significant for the further prognosis and therapy of neoplastic diseases.
Equine metabolic syndrome: Etiopathogenesis, diagnostics and therapy
Authors: Trailovic Dragisa , Trailovic Ivana , Spasojevic-Kosic Ljubica
Published: January 2016

Equine metabolic syndrome (EMS) is a term adopted in 2002 in aim to define
the complex pathology involving obesity, insulin resistance and laminitis in
horses and ponies. The EMS was terminologically derived upon similar
condition in humans. The metabolic disturbance in equines is developed
sequentially to the primary chronic overfeeding, i.e. intake of surplus food
to individual needs combined with insufficient activity of animal. The
syndrome has been reported more frequently in ponies than in other breeds
although genetic background of EMS has not been confirmed. The characteristic
symptoms include regional collection of adipose tissue under the skin often
distributed regionally i.e. in crest (neck from pool to withers), behind the
shoulders, at the dock of the tail and in prepuce in males or in the udder in
mares; as well as impaired locomotion and/or lameness in all four limbs and
cycling disturbance in mares.
Homeopathy in human and veterinary medicine
Authors: Cupara Snezana , Cupic Vitomir , Milovanovic Olivera , Radovanovic Ana , Kipic Mihailo
Published: January 2016

Classical homeopathy is a method belonging to complementary and alternative
medicine and is used in treatment of both people and animals. In human
medicine, classical homeopathy has a different status within the European
Union, depending on legislation that applies in the member countries
Veterinary homeopathy has currently being developed in three directions:
scientific researches are being conducted, animals are being treated by
homeopathy and education for homeopathic treatment of animals is being
organized as well. European Council for Classical Homeopathy (ECCH) in 2007.
published a report on homeopathic treatment of animals in Europe. The report
encompassed a variety of issues related to homeopathic treatment in
veterinary medicine in the countries of the European Union (EU) as well as
ECCH members, wherein the situation in Serbia is also mentioned. The current
veterinary homeopathy in Serbia is in the early development. Compared to the
moment of publication of the report, there is a slight positive change, but
there still lacks a standardized education and licencing system in this
field.
Does Recent Academic Research Support Changes to Audit Reporting Standards?
Authors: Bédard Jean , Coram Paul , Espahbodi Reza , Mock Theodore J.
Published: January 2016

SYNOPSIS

The Public Company Accounting Oversight Board (PCAOB), the International Auditing and Assurance Standards Board (IAASB), and the U.K. Financial Reporting Council (FRC) have proposed or approved standards that significantly change the independent auditor's report. These initiatives require the auditor to make additional disclosures intended to close the information gap; that is, the gap between the information users desire and the information available through the audited financial statements, other corporate disclosures, and the auditor's report. They are also intended to improve the relevancy of the auditor's report. We augment prior academic research by providing standard setters with an updated synthesis of relevant research. More importantly, we provide an assessment of whether the changes are likely to close the information gap, which is important to financial market participants and other stakeholders in the audit reporting process. Also, we identify areas where there seems to be a lack of sufficient research. These results are of interest to all stakeholders in the audit reporting process, as the changes to the auditor's report are fundamental. Additionally, our summaries of research on the auditor's report highlight where there is limited research or inconsistent results, which will help academics identify important opportunities for future research.