bluuebunny/crossref_metadata_2025 huggingface dataset:
MolScore: A scoring and evaluation framework for de novo drug design
Authors: Thomas Morgan , O'Boyle Noel M. , Bender Andreas , de Graaf Chris
Published: March 2024

MolScore is an open-source Python framework for scoring and evaluating molecules in the context of goal-directed generative models as used in de novo drug design. MolScore includes many relevant scoring functions for de novo drug design such as molecular similarity, docking software, predictive models, and synthesizability, as well as commonly used performance metrics to evaluate generative model performance based on chemistry generated. Integration into an existing generative model framework is simple, requiring just three lines of code, and graphical user interfaces are provided for objective configuration and for monitoring de novo molecules generated. As a real-world demonstration of its use, we use it to design selective 5-HT2a ligands using 266 pre-trained off-target predictive models, as well as docking into two co-crystal structures. MolScore can also be used for generative model evaluation as we demonstrate by analysing and selecting fine-tuning epochs of an RNN-based generative model. Moreover, the use of configuration files allows the sharing of objectives within the community for the purposes of reproducibility, comparison, and benchmarking; making it easier to propose drug discovery relevant objective functions as benchmark tasks. The code is freely available and hosted on GitHub, https://github.com/MorganCThomas/MolScore.
Impacts of Supercapacitor Electrode Structure on Electrochemical CO2 Capture
Authors: Xu Zhen , Mapstone Grace , Coady Zeke , Wang Mengnan , Spreng Tristan , Liu Xinyu , Forse Alexander
Published: March 2024

Supercapacitors are emerging as energy-efficient and robust devices for electrochemical CO2 capture. However, the impacts of electrode structure and charging protocols on CO2 capture performance, including the stability and CO2 selectivity over O2, remain unclear. Therefore, this study develops structure-property-performance correlations for supercapacitor electrodes at different charging conditions. We find that electrodes with large surface areas and low oxygen functionalization generally perform best, while a combination of micro- and meso-pores is important to achieve fast CO2 capture rates. With these structural features and tunable charging protocols, YP80F activated carbon electrodes show the best CO2 capture performance with a CO2 capture rate of 350 mmolCO2 kg–1 h–1 and a low electrical energy consumption of 18 kJ molCO2–1 at 300 A kg–1 under CO2, together with a long lifetime over 12000 cycles at 150 A kg–1 under CO2 and excellent CO2 selectivity over N2 and O2. Operated in a “positive charging mode”, the system achieves excellent electrochemical reversibility with Coulombic efficiencies over 99.8% in the presence of approximately 15% O2, alongside stable cycling performance over 1000 cycles. This study paves the way for improved supercapacitor electrodes and charging protocols for electrochemical CO2 capture.
Suppression of Salt Precipitation in Membrane Electrode Assembly Electrolyzers for CO2 reduction reactions by Intermittent Supply of Alkali Metal Cations
Authors: Kato Shintaro , Ito Shotaro , Nakahata Shoko , Kurihara Ryo , Harada Takashi , Nakanishi Shuji , Kamiya Kazuhide
Published: March 2024

The electrolysis of CO2 into value-added products holds great potential for closing the carbon cycle. A membrane electrode assembly (MEA) that uses solid polymer electrolytes is a critical technology for enhancing the energy efficiency for the CO2 reduction reaction (CO2RR) because a thin electrolyte layer can effectively reduce the ohmic resistance. The stable operation of the CO2RR in MEA-based cells with an anion-exchange membrane (AEM), however, is hindered by the accumulation of bicarbonate salts, which are derived from alkali-metal cations in anolytes, on the cathode side. Therefore, for stable operation of CO2 electrolysis using an MEA-based cell, the amount of alkali-metal cations needs to be reduced. However, the minimal amount of alkali-metal cations required to operate the reaction system has not been elucidated. Quantitative analysis of the amount of alkali-metal cations transported from the anode to the cathode is essential to obtain the insight into the necessary amount for the operation. In this study, we conducted a quantitative evaluation of the correlation between the production of high-value C2+ compounds, such as ethylene and ethanol, and the transported alkali-metal cations. As a result, although the presence of transported alkali-metal cations on the cathode surface significantly contributes to the generation of C2+ compounds, the rate of K+ ion transport did not match the selectivity of C2+. This result suggests a continuous supply of high amount of K+ to the cathode surface is not required for C2+ formation. On the basis of these findings, we achieved a faradaic efficiency (FE) and a partial current density for C2+ of 77% and 230 mA cm−2, respectively, even after switching the anode solution from 0.1 M KHCO3 to a dilute K+ solution (<7 mM) in an MEA-based cell using AEM and Cu nanoparticles as the cathode catalyst. These values of FE and partial current density were almost identical to those when 0.1 M KHCO3 was continuously supplied as the anode solution. Based on this insight, we successfully improved the durability of the system against salt precipitation. The FE for ethylene remained constant for as long as 60 h at 150 mA cm−2 when continuously flowing 0.1 M KHCO3 as anolyte. However, the FE suddenly decreased after 60 h due to the cessation of CO2 gas flow, caused by salt precipitation in the cathode flow channel. On the contrary, by intermittently supplying 0.1 M KHCO3, we confirmed that the amount of visible K+ salt in the cathode flow field remained negligible even after more than 90 hours of stable operation.
Introducing Type Ⅲ Metal Complex-Stabilized Olefin Radical Cation Induced Addition: A New Mechanism for Palladium-Catalyzed Wacker-Type Oxidation of Terminal Alkenes
Authors: Gu Liuqun
Published: March 2024

To expand the substrate scope of the recently named “Radical Cation Induced Addition (RCIA)”, allowing functionalization of inactivated alkenes, the concept of “metal complex-stabilized olefin RCIA” as a type III RCIA is introduced here, with a rational design on the delocalization of radical spin the via metal-olefin interaction and through space interaction with other ligands. The feasibility of Pd-olefin radical cation complex via one-electron oxidation enabled by an oxidant is demonstrated in the Pd-catalyzed Wacker-type oxidation of terminal alkenes. The new mechanisms involved with “Pd(II) to Pd(I) catalytic cycle” matches the reported kinetic data of both the Wacker process and the Tsuji-Wacker oxidation of olefins to ketones and/or aldehydes, and it could explain the long-time unexplained phenomenon of a water nucleophilic attack onto a negatively charged π-olefin coordinated with Pd atom. Furthermore, with the new mechanisms, the stereochemistry of the debated syn/anti attack and the regioselective control in Tsuji-Wacker oxidation for either ketones or aldehydes would also be well explainable. A new concept of “on Pd through space interactions” is too proposed to explain the root of the anti-Markovnikov selectivity by the resulted “through space conjugation”. Implications in the rational design of recyclable Pd precatalysts with a water-soluble ligand for aldehyde selective Tsuji-Wacker oxidation of olefins with the concept of “in-situ surfactant”, and implications for the rational design of domino/one-pot reactions toward sustainable complex molecules with functionalities starting from olefins, by merging with organocatalysis, are also included.
ANALYSIS OF INSECTICIDE SUSCEPTIBILITY DATA FOR DENGUE VECTORS USING INSECTICIDE RESISTANCE MANAGEMENT SYSTEM (IRMS)
Authors: R Rosilawati , YL Cheong , Khairuddin CI Mohd
Published: March 2024

Laboratory testing generates data, and data analysis contributes to the production of results that aid in problem resolution. As more samples are tested, more data is generated, and the complexity of data management increases. Surveillance monitoring and real-time assessment are crucial in managing insecticide resistance; consequently, manual management of insecticide resistance data requires digital transformation. The Insecticide Resistance Management System (IRMS) was developed in this study to analyse and manage 244 insecticide susceptibility data. This system permits immediate analysis following the entry of laboratory data. Red dots dominated green dots on a map displayed in IRMS depicting the prevalence of insecticide-resistant mosquito populations in both Aedes species. In addition, the heatmap revealed that the majority of Aedes aegypti were resistant to all tested insecticides during all monitoring cycles. This system circumvents the time-consuming limitations of manual data analysis by enabling rapid result visualisation and report generation.
Analisis Pengaruh Disiplin Kerja,Motivasi Kerja dan Lingkungan Kerja Terhadap Kinerja Pegawai dengan Teamwork Sebagai Variabel Moderasi
Authors: Wulandari Andri , Nurhayati Mafizatun
Published: March 2024

Penelitian ini bertujuan untuk menganalisis pengaruh disiplin kerja, motivasi kerja dan lingkungan kerja terhadap kinerja pegawai Sekretariat DPRD Kabupaten Cilacap dengan teamwork sebagai variabel moderasi. Populasi dalam penelitian ini adalah  pegawai pada Kantor Sekretariat DPRD Kabupaten Cilacap yang berjumlah 78 pegawai. Sampel penelitian ini berjumlah 78 orang yang dipilih dengan menggunakan teknik sampling jenuh. Penelitian ini bersifat kuantitatif dengan kuesioner sebagai alat untuk mengumpulkan data. Pengambilan data dengan wawancara dan kuesioner disusun dengan skala likert dan kemudian dihitung  software SPSS. Pengujian hipotesis menggunakan analisis regresi linier berganda dan regresi moderasi. Hasil penelitian ini menunjukan bahwa variabel disiplin kerja dan lingkungan kerja tidak berpengaruh  terhadap kinerja pegawai. Sedangkan motivasi kerja  memiliki pengaruh signifikan terhadap kinerja pegawai. Dan teamwork berperan sebagai variabel moderasi yang dapat memperkuat pengaruh lingkungan kerja terhadap kinerja pegawai. Pihak instansi harus memperhatikan dan meningkatkan faktor-faktor yang dominan dalam pembentukan variabel yang diteliti dalam penelitian ini sejalan dengan upaya untuk meningkatkan faktor-faktor lainnya yang berkaitan.
Who Can Span Industries? The Relationship among Category Spanning, Organizational Performance, Organizational Status, and Egocentric Uncertainty in the U.S. Venture-Capital Industry
Authors:   Korean Academy Of Management, Min Sanghoon , Jung Sumi , Kim Bo Kyung
Published: March 2024

This study examines how organizational status and egocentric uncertainty
mitigate the negative effects of category spanning on organizational
performance. Category spanning often leads to negative outcomes due to resource
constraints and audience confusion. We focus on category spanning
as an atypical combination of categories and identify two moderating factors,
namely organizational status and egocentric uncertainty, that can attenuate
these negative effects. First, we argue that high-status organizations involved
in category spanning are less likely to confuse audiences by being perceived
as distinctive and innovative, thereby reducing the likelihood of incurring
penalties typically associated with such activities. Second, egocentric uncertainty
enables similar resource allocation across categories, diminishing
the usual downsides of category spanning without necessarily increasing audience
confusion. To test our hypotheses, we analyzed U.S. venture-capital
industry data from 2008 to 2016. Our main variables included the atypicality
of the portfolio of investing industries, the status of the VC firm, and the
average stage of invested companies. We tested the effects of these variables
on the number of successful exits by utilizing negative binomial regression
models. The findings support our theoretical contentions: high-status VC firms
or those investing in ventures’ early stages are less susceptible to the negative
ramifications of category spanning on successful exits compared to their respective
counterparts.
High-Performance Work Systems and Innovation: The Moderating Effect of Low-Performance Management Practices
Authors:   Korean Academy Of Management, Choi Hyung Jin , Lee Ah-Young , Lee Sang-Min
Published: March 2024

Today, many organizations are pursuing innovation in order to survive in
a rapidly changing environment. As a result, based on resource-based theory,
organizations are introducing various human resource management practices
for the growth of workers toward innovation. However, the resulting effect
has not been the same for each company. This is because not enough consideration
has been given to the relationship between the newly established human
resource management practices and the existing practices of the company.
The synergy effect of human resource management practices may be weakened
or strengthened depending on how the sum of individual practices is bundled.
From this point of view, this study conducted an exploration of the synergy
between high-involvement work practices in high-performance work systems
and low-performance management practices to create innovation based on
the AMO framework. Specifically, the Korea Labor Institute's Workplace
Panel Survey analyzed the moderating effect of low-performance management
practices on the impact of high-involvement work practices for innovation.
According to the analysis results, high-involvement work practices had a positive
effect on innovation. In addition, the relationship between high-involvement
work practices and innovation was moderated positively by pull-type practices
among low-performance management practices. On the other hand, among
the low-performance management practices, push-type practices did not have
a significant moderating effect on the relationship between high-involvement
work practices and innovation. Based on the results, we discussed the need
for low-performance management and the direction for organizations pursuing
innovation in high-performance work systems.
Comparison of Apriori Algorithm and FP-Growth in Managing Store Transaction Data
Authors: Anas Syukron , Rumui Nelson , Roy Andi , Saputro Pujo Hari
Published: March 2024

The role and position of data in today's digital era are very important, data can be likened to a resource that can be explored further to produce new information or knowledge. Seeing the importance of data position, several solutions can be offered in getting more value from data, one of which is the use of Data Mining techniques with association techniques, several types of association techniques are a priori algorithms and FP-Growth algorithms. Based on the research results, the a priori algorithm produces a combination of goods with a confidence value of 98.4 and a support value of 98.4, and the algorithm produces a combination of goods with a support value of 95.2 and a confidence value of 95.2. The comparison of these two algorithms in making associations results in a faster execution time of the FP-Growth algorithm than Apriori, and the Apriori algorithm produces more varied itemset combinations.
Wrongfully Convicted: Guilty Pleas, Imagined Crimes, and What Canada Must Do to Safeguard Justice
Authors: Levy Tamara
Published: March 2024

NA
How Joint Enterprise Liability Neutered the Criminal Cases Review Commission in England
Authors: Hewitt Louise
Published: March 2024

In 2016 the English Supreme Court changed the law concerning joint enterprise liablity ub R v Jogee. The decision appeared to provide a remedy for secondary parties that had been convicted under the, albeit faithful application of the old law. The requirement, however, to demonstrate a substantial injustice following the subsequent case of Johnson significantly curtailed the number of appeals based on this change in the law. The substantial injustice test is applied by the English Criminal Cases Review Commission (CCRC) prior to the application of the statutory real possibility test. Up until now, there has not been any research that examines the impact of this situation and the extent that it constricts any remedy for secondary parties convicted under joint enterprise liability.  Using findings from the first study to explore this concept this work examines the limiting effect of the substantial injustice test on the CCRC, explores the application of the corrected law from Jogee, and shows the low number of applicants to the CCRC that identify as black British, despite existing research suggesting this demographic has the highest conviction rate for joint enterprise.
FILOSOFIA LEAN HEALTHCARE
Authors: Silva Leiliane Ribeiro e , Silva Yvanna Oliveira da , Gomes William Araújo , Cardoso Bruno Antunes , Nascimento Jaciane de Souza , Cardoso João Luiz Sousa , Matias Evila Ellen Sá de Moraes , Eleres Fabricio Bezerra , Moreno Francisca Chaves , Silva Jordana Cristine Dionizio da , Oliveira Andreza Paloma Góes , Moreira Vilzielle de Araújo , Matos Antonio Nilton Sousa , Cantão Jackson Luís Ferreira , Fernandes Victor Mateus Pinheiro
Published: March 2024

A Filosofia Lean Healthcare é uma abordagem que visa melhorar a eficiência e a qualidade dos serviços de saúde, adaptando os princípios da metodologia Lean, originalmente desenvolvida na indústria automobilística, para o contexto hospitalar. O foco principal dessa abordagem é a eliminação de desperdícios em todos os processos, garantindo que cada etapa agregue valor ao paciente. Isso inclui a redução de tempos de espera, a otimização do fluxo de pacientes, a melhoria da comunicação entre as equipes e a minimização de erros e retrabalhos. Ao implementar práticas Lean, os hospitais buscam aumentar a eficiência operacional e elevar a satisfação dos pacientes e dos profissionais de saúde.
Para a implementação efetiva da Filosofia Lean Healthcare, é fundamental que haja um comprometimento da liderança hospitalar e uma cultura organizacional voltada para a melhoria contínua. Isso envolve a capacitação das equipes em ferramentas Lean, como mapeamento de fluxo de valor, análise de causa raiz e metodologias de resolução de problemas. Além disso, é essencial estabelecer indicadores de desempenho claros para monitorar o progresso e identificar áreas que necessitam de melhorias. A implementação bem-sucedida requer uma abordagem sistêmica, integrando todos os setores do hospital e promovendo a colaboração interdisciplinar.
As práticas Lean Healthcare têm demonstrado resultados positivos em diversos hospitais ao redor do mundo, com reduções significativas nos tempos de espera, aumento da capacidade de atendimento, diminuição de custos e melhoria na qualidade do atendimento. No entanto, é importante reconhecer que a implementação dessa filosofia é um processo contínuo, que exige adaptação e evolução constantes para atender às mudanças nas demandas dos pacientes e aos avanços tecnológicos na área da saúde. A adoção da Filosofia Lean Healthcare representa uma importante estratégia para otimizar a gestão hospitalar, contribuindo para um sistema de saúde mais eficiente e centrado no paciente.
Cirugía bariátrica : Bypass gástrico laparoscópico
Authors: Susana Pretus Rubio  , Almudena Baños Maestro  , Irene Alonso Ramos
Published: March 2024

La obesidad es una enfermedad multisistémica y proinflamatoria cuya prevalencia está creciendo de manera exponencial durante los últimos años. La obesidad per se aumenta el riesgo de morbimortalidad perioperatoria, así como de complicaciones postquirúrgicas principalmente respiratorias, cardiovasculares y trombóticas. Uno de los puntos críticos para el anestesiólogo en cirugía bariátrica es el manejo adecuado de la vía aérea. En estos pacientes destaca una mayor incidencia de dificultad en la ventilación con mascarilla facial, más frecuente que la dificultad en la intubación. Es fundamental realizar una correcta preoxigenación y la adecuada colocación del paciente en la “posición en rampa”. Como técnica anestésica en el Hospital Universitario de Getafe se emplea la anestesia libre de opioides. Las recomendaciones para el manejo intraoperatorio de los pacientes intervenidos de cirugía bariátrica se deben extrapolar a todos los pacientes con obesidad que van a ser intervenidos de cualquier tipo de cirugía.
El misterio de los calcetines desparejados: Calidad de un modelo de regresión lineal.
Authors: Manuel Molina
Published: March 2024

Se revisan los parámetros que informan sobre la calidad de un modelo de regresión lineal múltiple y que habitualmente proporcionan los programas estadísticos con los que se realizan. Se hace hincapié sobre la bondad de ajuste, la capacidad predictiva y la significación estadística del modelo.
THEORETICAL BASIS OF RELATIONSHIP MARKETING OF UKRAINIAN HIGHER EDUCATION INSTITUTIONS
Authors: Panchuk Anastasiia , Kononova Nataliia
Published: March 2024

The main purpose of the article is to provide a thorough theoretical consideration of the concept of relationship marketing management of higher education institutions in modern conditions. The authors aim to define the theoretical foundations of this concept by analysing different approaches to its definition by different scholars, and to highlight the prerequisites for the formation of the concept of relationship marketing management in higher education institutions. In the article the authors consider in detail the nature and theoretical foundations of relationship marketing in Ukrainian universities. The paper highlights the prerequisites for the formation of the concept of relationship marketing management in Ukrainian higher education institutions. Particular attention is paid to the context of relationship marketing management in the context of the crisis in Ukraine due to the COVID-19 pandemic and the military conflict. The publication explores how these challenges affect the implementation of the relationship marketing management concept and considers key management strategies in this context. The article pays special attention to the study of the impact of digital transformations on the management of relationship marketing in Ukrainian universities. The authors analyse how the introduction of digital technologies creates new opportunities and challenges for relationship marketing management in higher education, especially in times of crisis. Based on this analysis, the authors propose an improved definition of the term "relationship marketing management of a higher education institution". They see it as a continuous process aimed at creating and sustaining value for all participants in this interaction. This improved definition takes into account the strategic orientation of relationship marketing management, which recognises the important role of universities in society. Furthermore, the article discusses the key actions required for the successful implementation of relationship marketing management in universities. The research proposes a classification of participants in the interaction of universities in the process of managing relationship marketing, distinguishing the categories of responsible actors, business partners, observers and regulators. This classification helps structure the university's interaction with various stakeholders and define their role in the context of relationship marketing management.
The Effect of Level-Marked Tasks on Students’ Mathematics Self-Efficacy and Persistence—Investigating a Tiered Activity
Authors: Herset Maria , Bjerke Annette H. , El Ghami Mohamed
Published: March 2024

In school mathematics, tiering tasks according to students’ readiness levels is a common approach to adapting content to address students’ varying abilities. To distinguish between different tiers, the tasks are commonly marked by their level of difficulty, as in so called level-marked tasks – a strategy used in differentiated instruction to help students gain mastery and improve performance. However, less is known about whether and to what extent the marking of the tasks works as intended. Regarded as a significant predictor of students’ performance in mathematics, the level marking of mathematics tasks and their effects on students’ self-efficacy and persistence were investigated. The online survey part of an experimental design was used to collect data from 436 lower secondary students in Norway. Independent sample t-tests and Mann–Whitney U tests revealed that, when students across groups were given the same mathematics tasks with and without level markings, tasks marked as difficult reduced both students’ mathematics self-efficacy and their persistence, even for students with high baseline self-efficacy. Although more research is needed to fully understand how the level markings of mathematics tasks affect students’ self-efficacy and persistence, the reported results have implications for both mathematics teachers and textbook authors.
Strategi Peningkatan Kepuasan Nasabah dengan Kualitas Pelayanan, Kepercayaan, dan Citra Perusahaan
Authors: Riedwindi Riedwindi , Sukati Inda
Published: March 2024

Tight competition makes it difficult for banks to maintain customer loyalty. This research aims to examine the influence of service quality, trust, and company image on customer satisfaction at CIMB Bank Niaga Lumbung Batam. The method used is a descriptive approach with a sample size of 215 respondents. The collected data was analyzed using a multiple linear regression model with the help of SPSS software. The results of multiple linear regression testing show that service quality has an effect of 27.1% on customer satisfaction. Trust has an effect of 16.1% on customer satisfaction, while corporate image has an effect of 39.0% on customer satisfaction. This means that there is a positive and significant relationship between service quality, trust, and company image, and customer satisfaction at CIMB Bank Niaga Lumbung Batam. The results of this research provide a strong basis for believing that by optimizing these three factors holistically, banks can increase the overall level of customer satisfaction and strengthen their position in the banking market.
Pengaruh Perbandingan Kinerja Keuangan Dua dari Lima Besar Perusahaan Farmasi Indonesia
Authors: Hakiki Moh. Saiful , Nugroho Mukhtar Adi
Published: March 2024

Knowledge about financial performance is considered very important for companies and investors. This research aims to compare the financial performance of two of Indonesia's top five pharmaceutical companies. This research uses financial ratio analysis, namely liquidity ratios, solvency ratios, activity ratios, profitability ratios, and market ratios. The method used in this research is comparative research using statistical analysis. The results of this research show that the first company has a higher liquidity and profitability ratio. In contrast, the second company has a better capacity to meet its interest obligations, even though its financial performance is more volatile. There were significant differences in twelve ratios between the two companies, and no significant differences were found in the other six ratios. Research findings can be a basis for the market to view that the first company has more potential to grow in the future and support the decision-making process for stakeholders.
Pengaruh Cyber-loafing terhadap Produktivitas dan Kinerja Tenaga Pendidikan Menggunakan Pendekatan Fenomenologi
Authors: Sugito Fefe Ali , Wirapraja Alexander
Published: March 2024

Cyber-loafing behavior, which is internet usage behavior that is not related to work, can hurt employee productivity and performance in the organization. This research aims to determine the impact of cyber-loafing on the productivity and performance of educational staff. The method used in this study was a phenomenological approach to measure the phenomenon of cyber-loafing behavior in the human resources aspect. The data collection technique used interview techniques with research informants at the state and private universities in Surabaya. The results show that cyber-loafing behavior influences the productivity and performance of education staff in their work environment. These findings can be the basis for educational institutions to control and supervise internet use by their employees.
Breves apuntes jurídicos sobre el término alumna, a propósito del monumento funerario de Lutatia Lupata en Augusta Emerita
Authors: Perea Yébenes Sabino
Published: March 2024

Se reexamina la famosa inscripción emeritense de Lutatia Lupata, en Mérida (Augusta Emerita) donde ésta, la difunta, aparece representada con un instrumento musical de cuerda. Aquí se centra la atención en el término latino alumna que aparece en el epitafio, indicando su estatuto en la inscripción, opuesto a la versión más difundida que relaciona este término con el aprendizaje del arte musical.
La Summa super Priscianum minorem de Petrus Helias (ca. 1140): tradición e innovación
Authors: Manzano Ventura Victoria
Published: March 2024

Aunque, en general, su importancia no se enfatiza lo suficiente, el tratado Summa super Priscianum minorem de Petrus Helias (ca. 1140) es uno de los de mayor difusión y trascendencia en el siglo XII. El objetivo de esta investigación es analizar la teoría sintáctica del tratado en sus presupuestos más destacados e innovadores. De este modo, el estudio expone las principales contribuciones y aportes sintácticos de la Summa super Priscianum minorem, señala sus fuentes y dependencias básicas, y rastrea el alcance de su influencia en el desarrollo gramatical posterior de la Baja Edad Media. El análisis realizado evidencia la decisiva influencia que la Summa super Priscianum minorem de Petrus Helias ejerce en el desarrollo y organización de la sintaxis desde la segunda mitad del XII y que llega incluso a los siglos XIII y XIV.
Herophilus on the (in)visibility of respiration
Authors: Bellini Elena
Published: March 2024

Herophilus of Chalcedon’s paramount advancements in the fields of anatomy and physiology are hailed as revolutionary not only in regard to their content, but also in regard to the methodology that made them possible. Concerning this latter point, later sources concur in attributing to Herophilus the use of human dissection (and possibly even of vivisection) for research purposes, an unprecedented practice that seems to have been abandoned and then systematically retrieved only in the sixteenth century by Leonardo da Vinci and Vesalius. Herophilus’ audacity in the field of anatomical inquiry was nevertheless accompanied by a rather cautious approach to aetiology. “Let the appearances be described first, even though they are not primary” (An. Lond., XXI., 22-3): the medical practitioner must rely on what is visible, even though what is visible is not necessarily sufficient to an exhaustive comprehension of physiological phenomena, nor is it always at one’s disposal. Such a tension between the visible and the invisible, the perceptible and the imperceptible, lies at the very basis of Herophilus’ inquiry of the human body, extraordinarily lucid in defining its own limits. Through this article I propose to focus on the particular case of respiration, subject of the chapter of the Aëtian Placita known under the title Περὶ ἀναπνοῆς, as an example of the Herophilean reflection about the theoretic observability of phenomena that, far from being marginal or occasional, deserves to be recognised as a fundamental part of his epistemology.
El bronce epigráfico de Monteagudo (Murcia), ¿el documento jurídico de una olvidada civitas?
Authors: Martínez Chico David
Published: March 2024

El bronce epigráfico que a continuación vamos a comentar, procedente de Monteagudo, es conocido desde hace más de un siglo. En origen, se trató de una gran tabula, grabada para ser expuesta en un edificio público. Por desgracia, solo nos ha llegado la noticia de un pequeño fragmento, hoy día desaparecido (es probable que el fragmento acabara fundido). Basándonos en una nueva lectura, proponemos que dicho documento fue jurídico (no necesariamente una lex o tabula hospitalis). Como complemento, se abordan las evidencias arqueológicas que hay en Monteagudo, concluyendo que fue un núcleo urbano, de época altoimperial y del sur de la Tarraconense. Finalmente, la entidad de esta civitas queda patente por la citada tabula.
BUSINESS PARTNERSHIPS, PERSONNEL COMPETENCY, AND MARKETING STRATEGIES INFLUENCING THE SUCCESS OF TOURISM BUSINESS OPERATIONS IN THAILAND
Authors:   Suan Sunandha Rajabhat University, Business Administration, Faculty of Management Science, Bangkok, Thailand, POTJANAJARUWIT Pisit , KLAYSUNG Somsak ,   Suan Sunandha Rajabhat University, Business Administration, Faculty of Management Science, Bangkok, Thailand, SUKAVEJWORAKIT Krisakorn ,   Mahidol University, Nakhon Pathom, Thailand
Published: March 2024

In this study, an attempt has been made to examine factors affecting the success of various types of tourism business in Thailand. A total of 100 copies of the questionnaires were given to operators and managers engaged in tourist businesses in Thailand. These respondents were chosen by Proportionate Random Sampling-a method that ensures an unbiased cross-section from every section of society. The statistical methods used in data analysis include percentage calculation ; determining a mean value for all readings ; assessing standard deviation; analysing frequencies and multiple regression analysis. Entrepreneurs in Thailand's tourism industry have indicated that for the success of their operations marketing strategy, personnel competency, and business partnerships are the most important factors. When the study carried out the hypothesis tests it showed that price, place, and product (the 4Ps of marketing mix) location, and physical surroundings on one hand skills of human resource management to bring employees together while business partnership are positively correlated with success in operating a tourism business statistically.
An approach for constructing a two-element antenna array based on the Cramer-Rao lower bound for direction-of-arrival estimation of radio signals with super-resolution and increased accuracy
Authors:   Bunin Yelets State University, 399770, Russia, Yelets, Kommunarov st., 28, Peshkov I.W.
Published: March 2024

In the paper an effective method for optimal placement of directional antenna elements for digital spatial signal estimation is discussed. The digital antenna array evaluates spatial coordinates with the subsequent beamforming. However, as it is well known, the relative position of antenna elements, their number and the shape of the radiation pattern have a significant impact on the quality of the spatial pseudospectrum. The paper uses the previously obtained expression for estimating the Cramer-Rao lower bound to reduce the number of antenna elements without losing the accuracy of direction-of-arrival estimation of the signals. For example, a two-element array is obtained. The elements have a flat-top radiation pattern. It is shown that the accuracy of the MUSIC method in the obtained array is higher or comparable to the array composed of three elements.
Senderos de lucha. Las izquierdas mexicanas durante la época de la Guerra Fría
Authors: Reynoso Jaime Irving , Velázquez Vidal Uriel
Published: March 2024

El desarrollo de las izquierdas mexicanas que estudiamos en esta obra se enmarcó en la llamada Guerra Fría (1947-1989), una pugna mundial que se dio entre los dos grandes bloques político-ideológicos del momento, el socialismo y el capitalismo, encabezados por la Unión Soviética y Estados Unidos. Desde luego, ni México ni ningún Estado pudo desentenderse de ese choque de visiones antagónicas del mundo. El contexto mexicano se caracterizó por las condiciones de pobreza e injusticia social que padecían grandes sectores de la población. Ante esto, se desarrollaron amplias movilizaciones que fueron paulatinamente radicalizando sus posiciones impulsadas por la represión gubernamental. De este modo, algunos pensaron que los cauces legales estaban cerrados y que la única forma de transformar la realidad era a través de la vía armada; otros decidieron cambiar las reglas del régimen a través de la participación en los partidos políticos, pues consideraron que el cambio sólo se podía hacer desde dentro del sistema; finalmente hubo quienes criticaron a los reformistas y a la vez cuestionaron el camino de las armas, por lo que optaron por el trabajo de concientización en fábricas, sindicatos, ejidos, barrios marginales y colonias populares. Así, el libro presenta análisis sobre la praxis de las izquierdas mexicanas durante la época de la Guerra Fría, dividiendo los trabajos en tres ejes de investigación: izquierda armada, izquierda partidista e izquierda social (o de los movimientos sociales). El lector encontrará planteamientos teóricos y conceptuales, discusiones historiográficas, cuestionamientos a visiones tradicionales, novedosas fuentes de archivo, concienzudos análisis históricos, testimonios de militantes y protagonistas de varios de los procesos aquí estudiados. Esperamos que este trabajo sea de utilidad e interés para el público, y que motive mayores indagaciones sobre el papel que han jugado las izquierdas en la historia contemporánea de México.
Vala Comum de Perus: lugar de memória e resistência
Authors: Ansara Soraia , Besen Beatriz
Published: March 2024

O presente artigo tem como objetivo analisar os processos de memória construídos a partir da abertura da Vala Comum de Perus, apresentando-a como "lugar de memória" que possibilita a reconstrução da memória da ditadura militar brasileira a partir de ações culturais, educativas e artísticas, assim como celebrações e rituais desenvolvidos por coletivos, organizações e movimentos sociais. Abordamos as políticas de memória e esquecimento no Brasil, as disputas entre a memória oficial hegemônica e as memórias subterrâneas e marginais e, por fim, analisamos a Vala Comum de Perus como um lugar-símbolo de memória que mobiliza novas expressões artísticas e políticas que aproximam diversas gerações na luta contra a violência de Estado.
Criminalización y deslegitimación de la demanda territorial mapuche en la prensa escrita argentina
Authors: Aramayo Eliazarian Hairenik
Published: March 2024

Este trabajo analiza la construcción social del pueblo mapuche y sus reclamos territoriales en el diario argentino La Nación a partir de un corpus de artículos publicados en 2017 luego de la toma de un predio estatal. Para el análisis, seguimos la propuesta metodológica de la “Lingüística Crítica” de Hodge y Kress (1979), que postula que una gramática es una teoría sobre la realidad que configura una visión del mundo y que nos brinda categorías para clasificar los eventos de éste. El análisis sintáctico-semántico permitió relevar las distintas estrategias a partir de las que el pueblo mapuche es construido como un otro peligroso y violento, su identidad es des-marcada (Kropff) al borrar su historia y su lucha territorial, deslegitimada.
Arte y género en Baja California
Authors: Medellín Martínez Martha Patricia
Published: March 2024

El presente artículo reúne y describe las prácticas artísticas feministas del Archivo Arte y Género de Baja California, recuperadas a través de una metodología autoetnográfica, así como los antecedentes regionales y locales más sobresalientes desde el año 2010 a la fecha, que motivaron e impactaron al proyecto, y las colaboraciones con institutos culturales locales y nacionales, con agentes creativos, docentes y activistas. Lo anterior con el objetivo de aportar a la memoria artística bajacaliforniana una reflexión sobre los cruces con los estudios de género desde los esfuerzos individuales de un grupo emergente.
Algorithm for surgical treatment of gastroduodenal ulcer with multiple combined complications
Authors: Ivanchov P. V. , Bilyachenko M. V.
Published: March 2024

Surgical management of gastroduodenal ulcers (GDU) and multiple combined complications (MCC) remains a relevant, complex and unresolved issue. There are currently no well‑defined algorithms, strategies, or surgical procedures for the treatment of gastroduodenal ulcers accompanied by a variety of complications.
Objective —  to improve the results of surgical treatment and reduce the mortality of patients with GDU and MCC by implementing a surgical treatment algorithm.
Materials and methods. The results of surgical treatment of patients with complicated GDU for the period 2000—2022 are presented. A total of 395 (100.0%) patients with GDU accompanied by MCC (a combination of two or more complications) were operated on. There were 52 (13.16%) patients with gastric ulcer perforation and 301 (76.2%) patients with duodenal perforation. A combination of two complications was noted in 299 (75.69%) patients, three — in 88 (22.28%) patients, and four — in 8 (2.03%) patients.
Results. A total of 352 (89.11%) operative interventions were performed in an emergency, 43 (10.88%) were performed in the early delayed period (EDP). The implementation of a new algorithm of surgical treatment in the main group and the use of modern measures of endoscopic hemostasis made it possible to increase the rate of operated patients in EDP by 2.6 times, and reduce the mortality rate from 10.14% to 6.45%. The highest rate of mortality is associated with gastric resection in patients with GDU and MCC — 3 (42.87%) out of 7 patients. The lowest mortality rate was among patients who underwent one of the types of organ‑saving surgery — 7 (2.86%) patients out of 245 operated on in this group.
Conclusions. The implementation of the algorithm for providing surgical care to patients with GDU accompanied by MCC made it possible to reduce intraoperative mortality from 10.14% to 6.45%. The use of modern means of endoscopic hemostasis made it possible to stabilise, adequately prepare, and operate patients in EDP, which is confirmed by the increase of this indicator in the main group by 2.6 times. The highest mortality rate was in patients who underwent gastric resection and was 42.87%.
POTENSI SELEDRI (Apium graveolens L) DAN STROBERI (Fragaria sp) SEBAGAI MINUMAN FUNGSIONAL APIGA TERHADAP TEKANAN DARAH
Authors: NUGRAHASARI CATURINI MEIDYA , Sutjiati Endang , Mustofa Annasari
Published: March 2024

Hipertensi merupakan salah satu penyakit tidak menular yang menjadi permasalahan kesehatan di dunia, berdasarkan data Riskesdas, prevalensi penderita hipertensi pada penduduk umur ?18 tahun di Indonesia mengalami peningkatan dari 25,8% pada tahun 2013 menjadi 34,1% pada tahun 2018 (Kementrian Kesehatan, 2019). Seledri memiliki kelemahan pada cita rasa maka perlu di tambahkan bahan makan lain yaitu stroberi serta di beri nama yaitu Minuman APIGA dari nama latin, seledri (Apium graveolens L) dan stroberi (Fragaria sp). Tujuan dari penelitian ini adalah untuk mengetahui potensi seledri (Apium graveolens L) dan stroberi (Fragaria sp) sebagai minuman fungsional APIGA (Apium dan Fragaria) terrhadap tekanan darah sistolik dan diastolik pada penderita Hipertensi rawat jalan di Puskesmas Yosomulyo Banyuwangi. Jenis penelitian adalah Pre eksperimental, dengan rancangan one grup pretest-pottest, dengan responden 30 pasien. Pemberian minuman 1 kali seharu selama 3 hari berturut-turut sebanyak 250 ml/g. Uji normalitas menggunakan Shapiro Wilk. Analisis statistik menggunakan uji wilcoxon signed test dan paired t-test. Rata-rata tekanan darah sistolik sebelum diberikan intervensi minuman fungsional APIGA adalah 162,23 mmHg dalam kategori hipertensi tahap II dan rata-rata tekanan darah diastolik adalah 94,67 mmHg termasuk dalam kategori hipertensi tahap I. Rata-rata tekanan darah sistolik sesudah diberikan intervensi minuman fungsional APIGA adalah 145,57 mmHg dalam kategori hipertensi tahap I dan rata-rata tekanan darah diastolik adalah 84,20 mmHg termasuk dalam kategori rehipertensi. Dapat disimpulkan ada pengaruh signifikan antara tekanan darah sisitolik dan diastolik penderita hipertensi sesudah diberikan intervensi minuman fungsional APIGA Terhadap Tekanan Darah Penderita Hipertensi Rawat Jalan di Puskesmas Yosomulyo Banyuwangi dengan p value = 0,000.
FORMULASI TEPUNG MOCAF, TEPUNG KACANG HIJAU, DAN TEPUNG IKAN SELAR TERHADAP NILAI ENERGI, MUTU KIMIA, DAN MUTU ORGANOLEPTIK COOKIES SEBAGAI PMT ANAK SEKOLAH
Authors: Permana Bayu Daeka , Razak Maryam , Pudjirahaju Astutik
Published: March 2024

Riset Kesehatan Dasar 2018 melaporkan 9,2% anak usia sekolah di Indonesia memiliki status gizi kurus. Lebih lanjut, 16 provinsi dengan prevalensi status gizi kurus anak usia sekolah ? 10%. Prevalensi gizi kurus anak usia sekolah dianggap masalah kesehatan yang serius apabila berkisar 10,0 - 14,0%.  Kurangnya asupan makanan merupakan salah satu penyebab status gizi kurus pada anak sekolah. Salah satu program pemerintah untuk mencukupi kekurangan gizi anak usia sekolah dengan pemberian PMT-AS. Pengembangan produk cookies PMT-AS melalui pemanfaatan pangan lokal yaitu umbi-umbian, kacang-kacangan dan ikan dengan memperhatikan zat  gizi serta daya terima secara organoleptik. Tujuan Penelitian untuk menganalisis pengaruh formulasi tepung mocaf, tepung kacang hijau dan tepung ikan selar terhadap mutu kimia, nilai energi dan mutu organoleptik cookies sebagai PMT-AS.  Jenis Penelitian eksperimen laboratorium desain penelitian Rancangan Acak Lengkap (RAL) dengan perlakuan proporsi tepung mocaf, tepung kacang hijau dan tepung ikan selar. Penelitan menggunakan 3 taraf perlakuan dengan 3 replikasi.  Hasil penelitian formulasi tepung mocaf, tepung kacang hijau dan tepung ikan selar memberikan pengaruh signifikan terhadap kadar air, kadar abu, kadar karbohidrat aroma dan rasa cookies. Namun demikian, memberikan pengaruh yang tidak signifikan terhadap kadar protein, kadar abu, kadar lemak, kadar energi, warna, dan tekstur.  Taraf perlakuan (P1) merupakan taraf perlakuan terbaik.
PROMOSI KESEHATAN PADA ANAK SEKOLAH DASAR DALAM PENINGKATAN PENGETAHUAN PERILAKU HIDUP BERSIH DAN SEHAT (PHBS ) DI SD AL- IRSYAD KOTA BATU
Authors: Rahmadina Sylvia Alda , Lala Handy , Halis Farida
Published: March 2024

Anak sekolah menjadi salah satu kelompok paling rentan terhadap terjadinya masalah kesehatan karena faktor lingkungan dan pola hidup yang kurang baik. Kondisi ini harus segera diantisipasi dengan meningkatkan pola hidup sehat melalui PHBS. Salah satu upaya dalam promosi kesehatan dalam meningkatkan pengetahuan adalah melakukan pendidikan kesehatan mengenai perilaku hidup bersih dan sehat khususnya di sekolah. Tujuan dalam penelitian ini adalah untuk mengetahui pengaruh promosi kesehatan pada anak sekolah dasar dalam peningkatan pengetahuan perilaku hidup bersih dan sehat (PHBS) di SD Al-Irsyad Kota Batu. Dalam Penelitian ini metode penelitian yang digunakan adalah penelitian kuantitatif dengan menggunakan desain Pra-Eksperimen atau Pre Experimental Design dengan pendekatan One Group Pretest Posttest Design. Teknik pengambilan sampel dalam penelitian ini adalah purposive sampling dengan kriteria inklusi dan eksklusi. Dalam penelitian ini yang menjadi sampel yakni siswi kelas 4 berjumlah 34 orang. Berdasarkan hasil penelitian menunjukkan pengetahuan sebelum diberikan promosi kesehatan memiliki pengetahuan cukup dengan presentase 44,12% dan memiliki pengetahuan kurang dengan presentase 55,88%, dan setelah diberikan promosi kesehatan responden memiliki pengetahuan baik dengan presentase 100%. Terdapat pengaruh promosi kesehatan terhadap peningkatan pengetahuan pada siswa, berdasarkan hasil uji statistik menunjukkan 0.000 0.05 maka hipotesis diterima. Kesimpulannya adalah ada pengaruh promosi kesehatan terhadap pengetahuan pada anak sekolah dasar mengenai PHBS pada siswi kelas IV di SD Al-Irsyad Kota Batu.