bluuebunny/crossref_metadata_2025 huggingface dataset:
Severe pneumonia caused by Chlamydia psittaci: report of two cases and literature review
Authors: Dai Nini , Li Qiuyu , Geng Jiayi , Guo Wei , Yan Wei
Published: July 2022

Introduction: Chlamydia psittaci pneumonia is a zoonotic infectious disease caused by Chlamydia psittaci. Its clinical manifestations are nonspecific. Diagnosis of the disease is difficult. In recent years, next-generation sequencing has played an important role in pathogen detection. We report two cases with severe Chlamydia psittaci pneumonia confirmed by next-generation sequencing.
Case Study: The first case is that of a 50-year old man who presented with high fever for four days and cough with sputum for two days. The second case is that of a 57-year-old man who was admitted with high fever for one week, dyspnea and cough with sputum for four days. The second man worked at a chicken farm in the last two months. In both cases, the usual laboratory examination for pathogens detection was negative, and the initial anti-infectious therapy had limited effect. The bronchoalveolar lavage fluid of case 1 and the blood and sputum of case 2 were sent for next-generation sequencing which resulted in sequence reads of Chlamydia psittaci. Antibiotics were adjusted according to the diagnosis.
Results: The diagnosis of the two cases was confirmed by next-generation sequencing detecting Chlamydia psittaci, and the patients had positive results after treatment.
Conclusions: The two cases suggest that next-generation sequencing could be used in early diagnosis of Chlamydia psittaci infection to initiate specific anti-infection therapy in time.
Laparoscopic Single Anastomosis Sleeve Ileal Bypass with Follow-up of Weight Loss and Metabolic Impact
Authors: Abdalaziz Ahmad , Sarhan Mohamed D. , Abou-Eisha Hesham Ahmed , Abdelsalam Ahmed , Saqr Ahmed , Fathy Ehab
Published: July 2022

Background: Bariatric surgery has been an effective safe management for severe obesity. The newly developed single-anastomosis sleeve ileal (SASI) bypass has shown efficacy as a functional as well as mechanical restrictive bariatric procedure, with a neuroendocrine modulation effect. SASI bypass is still an investigational procedure, hence, more evidence is needed till it is declared as a standard bariatric procedure by the IFSO. Aim of the study: The current work aimed to describe our experience regarding the technical steps, the efficacy and the short-term outcome of SASI bypass procedure in patients with severe obesity. Patients and methods: Forty seven patients with severe obesity underwent SASI bypass procedure. They were followed till 1 year postoperatively. The weight loss, comorbidities and laboratory changes were assessed. Results: Patients evaluation at the 1-year postoperative follow up revealed a mean %TWL of 37.55 ± 6.17 and a mean %EBWL of 76.21 ± 9.8. The remission rates of T2DM, hyperlipidemia and hypertension were 85.7%, 94.7% and 89.66%, respectively, with statistically high significant differences between the preoperative and 1-year postoperative comorbidities rate. Stepwise regression analysis demonstrated that only the preoperative HbA1C remained in the model predicting the %TWL, and the preoperative BMI was the remaining factor in the model predicting the %EBWL in the study patients. Conclusion: The present study adds a new evidence to the promising outcome of the newly introduced SASI bypass procedure. After one year, the study patients showed excellent weight loss and comorbidities remission together with acceptable major complication rates.
Effect of Diode Laser and Remineralizing Agents on Microstructure and Surface Microhardness of Therapeutic Gamma-Irradiated Primary Teeth Enamel
Authors: Atef Rasha , Zaky Ahmed Abbas , Waly Nevin , El Rouby Dalia , Ezzeldin Naglaa
Published: July 2022

BACKGROUND: Radiation caries is a serious complication to head and neck cancer (HNC) radiotherapy, for which the primary teeth are more susceptible to be affected. Preventive protocols are recommended to enhance dental structure resistance against the direct effects of radiotherapy.

AIM: The aim of the study is to evaluate the effect of diode laser and two types of remineralizing agents on the microhardness of the primary teeth enamel and examine microstructural alterations.

METHODS: Twenty primary molars were sectioned into two halves in a mesiodistal direction, to obtain 40 specimens, which were then randomly allocated into five groups. Group 1 (Control Negative) n = 5 was not subjected to any treatment or radiation. Group 2 (Control positive) n = 5 was gamma irradiated with a dose of 60 Gray. For Groups 3, 4, and 5, specimens were divided into two subgroups: A and B (n = 5/subgroup). Subgroups A were gamma irradiated, then exposed to different surface treatments: 3A:10% nano-hydroxyapatite (nHA) paste, 4A: 5% sodium fluoride varnish (FV), and 5A: diode laser 980 nm. Subgroups B were exposed to surface treatments (3B: 10% nHA, 4 B: 5% FV, and 5B: diode laser 980 nm), then gamma irradiated. Surface micromorphology and microhardness were examined using environmental scanning electron microscope (ESEM), and Vickers microhardness tester, respectively.

RESULTS: Group 2 (G) specimens possessed the lowest mean microhardness, while nHA-G (3B), G-Fl (4A), and L-G (5B) had significantly higher values. ESEM analysis showed an alteration in Group G and the obliteration of enamel micropores with remineralizing agents. The melting and fusion of enamel in laser subgroups were also observed.

CONCLUSIONS: The findings indicated that using FV, nHA, or diode laser increased microhardness and maintained the integrity of the enamel microstructure. Therefore, applying preventive strategies should be considered in HNC radiotherapy.
The Role of Prophylactic Cervical Lymph Node Dissection with Total Thyroidectomy in Prevention Recurrence of Papillary Thyroid Carcinoma
Authors: Kadhim Salah Hadi , Mahmood Karrar Ibrahim , Habash Mohammed Mohammud
Published: July 2022

AIM: It is assess benefit prophylactic selective unilateral cervical lymph node (LN) dissection with total thyroidectomy for patients who have papillary thyroid carcinoma (PTC) and negative cervical lymph nodes metastasis and determination recommended risk factors for such surgery.

METHODS: This was a prospective study, 60 patients with PTC investigated by Fine needle aspiration, ultrasonography to support diagnosis patients with PTC, and negative lymph node metastasis. Nineteen patients are excluded from the entire 60 patients; remaining 41 patients are submitted to a total thyroidectomy and prophylactic selective one side ipsilateral lateral and central lymph nodes dissection (level II, III, IV, and V). Then, follow-up 2 years for all patients, postoperatively, for detection PTC recurrence.

RESULTS: The result shows that from the total 41 patients, two groups are positive and negative lymph nodes metastasis 24.4% (10) and 75.6% (31), respectively, positive lymph nodes metastasis is presented more in male 7 (70%) with significant difference (p = 0.03) and age groups <55 years old 6 (60%) with insignificant association (p = 0.413). Thyroid nodular size (>1 cm) and multiple nodules presented more in positive lymph nodes metastasis with significant difference in both. Multivariate binary logistic regression, sex, thyroid multinodularity, and thyroid nodule size were insignificant relationship of prediction of lymph nodes metastasis.

CONCLUSION: Prophylactic cervical LN dissection with total thyroidectomy for patients with PTC and negative cervical lymph nodes metastasis has beneficial role in preventing recurrence of PTC. Risk factors such as male gender, thyroid multinodularity (multiple nodule), and their size (>1 cm) have role in increasing chance of occurrence of cervical LN metastasis.
Correlation between HbA1C and Infarct Volume in Acute Ischemic Stroke
Authors: Mirawati Diah Kurnia , Riany Navidya Ade , Subandi Subandi , Hamidi Baarid Luqman , Rahayu Rachmi Fauziyah , Budianto Pepi , Hafizhan Muhammad , Putra Stefanus Erdana
Published: July 2022

BACKGROUND: Stroke is second leading cause of death worldwide. Chronic hyperglycemia can promote neuronal toxicity. The previous study shows that acute hyperglycemia is correlated with infarct volume of ischemic stroke. AIM: This study aims to investigate the correlation between hemoglobin A1C (HbA1C) and infarct volume on acute ischemic stroke. METHODS: This is a cross-sectional study in acute ischemic stroke patient in Dr. Moewardi General Hospital, Surakarta, Indonesia. Data of infarct volume were collected from head computed tomography (CT)-scan and calculated with A × B × C/2 formula. We also collected lipid and patients’ glycemic profile from patients’ blood laboratory result. Head CT-scan and laboratory data of participants analyzed with Pearson and Spearman’s rho test for parametric and non-parametric data, respectively. We also performed multivariate analysis to evaluate confounding covariates. p < 0.05 was considered as statistically significant. RESULTS: A total of 38 participants were included in this study, with mean infarct volume was 0.46 ± 0.64cc and mean HbA1C was 6.96 ± 2.69%. Bivariate analysis shows strong positive correlation between infarct volume and HbA1C with r = 0.898 (p < 0.001). Other variable that showed a significant correlation with infarct volume were diabetes mellitus history (r = 0.671; p < 0.001), random blood su gar (r = 0.466; p = 0.003), fasting blood sugar (r = 0.636; p < 0.001), 2-h postprandial glucose level (r = 0.646; p ≤ 0.001), high density lipoprotein (r = −0.354; p = 0.029), and triglyceride (r = 0.429; p = 0.007). Based on multivariate analysis, HbA1C regression coefficient on infarct volume was B = 0.222 (p < 0.001), indicating that HbA1C as one of the variables contributing to volume of infarct. CONCLUSIONS: There is a strong positive correlation between infarct volume and HbA1C, and HbA1C is variable contribute to the volume of infarct.
Epidemiological Trend Analysis and Survival Data of Balinese with Soft-Tissue Sarcoma in 2015–2021
Authors: Sudarsa I. Wayan , Aryanti Citra
Published: July 2022

BACKGROUND: Soft tissue sarcoma (STS) has a very heterogen features of its nature, subtypes, and clincial behaviour among population. Regardless, the epidemiology data of soft tissue sarcoma is very limited in developing countries, including Indonesia.
AIM: To decribe the incidence and mortality trend analysis, as long as the survival data in Bali from 2015 to 2020.
METHODS: This is a case control study including all subjects with STS in Denpasar, Bali, Indonesia from January 2015 to September 2021. Data about demographics, clinical, and survival timing data were collected from Cancer Registry. Soft tissue sarcoma diagnosis was confirmed after histopathological examination. Joinpoint regression was used for crude rate trend analysis. Data was analyzed by SPSS 22.0, using Kaplan-Meier for survival analysis.
RESULTS: Ninety three subjects with STS were included in this study. Most patients died at the end of the study (65.6%) with median survival of only 30 months. The trend of STS age-standardized incidence and mortality rate was increasing from 2015 to 2018, then declining until 2020. The survival rate varies among the soft tissue sarcoma subtypes and location. It was better in the group without metastases, underwent therapy, but not statistically significant.
CONCLUSION: Soft tissue sarcoma showed a diversity of demographic and clinical parameters. The incidence and mortality rate has plateued in 2018, but then declining. The survival rate diversed regarding of the STS subtype, location, metastasis, and treatment given.
Unilateral versus Bilateral Femoral Arterial Access for Uterine Artery Embolization
Authors: Ali Hossam Mohsen Hassan Hussein , Abdel-Wahab Sameh Mohamed , Abdel-Samad Amr Mahmoud , El-Shimy Ahmed
Published: July 2022

Background: Uterine fibroids are the most common benign tumors in women. Their clinical presentation includes menorrhagia, metrorrhagia, lower abdominal pain and infertility. Treatment of uterine fibroids includes medical management, surgical resection known as myomectomy as well as minimally invasive options like uterine artery embolization. Uterine artery embolization can be done via unilateral or bilateral femoral arterial access. We aim to define the differences between unilateral and bilateral femoral access in concern to radiation dose, procedure time , fluoroscopy time as well as the number of angiographic images.
Methods: A total of 48 patients were divided into two groups equally; one with a unilateral femoral access and the other group with a bilateral femoral arterial access.
Results: The age of the patients ranged between 25 to 40 years, embolization was done with calibrated spheres. Bilateral procedures compared to the unilateral ones had less fluoroscopy times (8.6 minutes vs 24.3 mins) , less total procedure time (28.4 minutes vs 54.4 minutes) and less dose area product (155 Gy cm2 vs 340.5 Gy cm2) as well as less mean number of angiographic images (93.8 vs 176.5) with no significant difference in puncture site complications.
Conclusion: Fluoroscopy times, procedure times, number of angiographic images as well as radiation dose were significantly lower in the bilateral approach with no significant difference in the rates of puncture site complications between the two approaches.
Keywords: Uterine Artery Embolization, uterine fibroids, unilateral versus bilateral access.
Why legal standards in antitrust enforcement in developing jurisdictions should differ from those in mature jurisdictions: A decision-theoretic approach
Authors: Katsoulacos Yannis
Published: July 2022

The appropriate choice of legal standards (LSs) in antitrust enforcement, that is, decision procedures or decision rules that provide the basis for how potentially anticompetitive conduct must be assessed in order to decide whether there is liability or not, has been hotly debated for many years. The debate has gained in intensity in recent years as a result of the concerns expressed by a significant number of academics and policy makers in many countries about the antitrust treatment of major platforms. Relying on recent developments in the literature on the choice of LSs, this article shows that the adoption of presumption-based LSs, that is, LSs that are closer to Per Se than to Effects-Based in developing jurisdictions, and the standards that would be optimal in developed jurisdictions, is consistent with the principles of minimising the costs of decision errors, and also leads to lower enforcement costs. The standards that would be optimal in developed jurisdictions, is consistent with the principles of minimising the costs of decision errors, and also leads to lower enforcement costs.
L’hérédité pour les zootechniciens français de la seconde moitié du XIX e siècle
Authors: Marty Bernard
Published: July 2022

Autant la contribution des botanistes-praticiens à l’étude de l’hérédité au xix e  siècle est connue, autant celle de leurs homologues zoologistes, en la matière, l’est moins. Nous tentons ici de combler cette lacune et de donner un aperçu de leurs conceptions à partir du moment où la pratique de l’élevage, vers le milieu du siècle, s’inscrit dans une discipline nouvelle, la zootechnie.
Professionnaliser par les valeurs ?
Authors: Poulet Manuel
Published: July 2022

L’obtention d’un diplôme d’Etat est indispensable pour que les travailleurs sociaux puissent exercer en tant que professionnels. Pour autant, ce diplôme n’est qu’une étape dans un parcours de professionnalisation plus large et plus long que le parcours de formation. L’article vise à identifier la manière dont les valeurs, intrinsèquement liées aux professions du secteur social et à leur construction, participent à la professionnalisation des travailleurs sociaux en portant une attention particulière au rôle des encadrants.
AFEST : quelles incidences sur la professionnalisation des formateurs ?
Authors: Petit Lucie , Lejeune Laurence , Gantier Fabienne , Ghesquière Isabelle , Sallard Florence
Published: July 2022

Introduite dans l’appareil de formation professionnelle continue français avec la loi du 5 septembre 2018 pour la liberté de choisir son avenir professionnel, l’AFEST rompt avec le modèle dit « séparatiste » prédominant dans les relations formation et travail depuis 1971. Comment cette nouvelle modalité pédagogique affecte-t-elle les acteurs de la formation ? Pour amorcer une réponse à cette question, nous nous focaliserons sur les entretiens de formateurs/formatrices travaillant en organisme de formation, et ayant participé à une courte expérimentation incluant des AFEST à destination de personnes en recherche d’emploi du Nord et du Pas-de-Calais.
Les règles d’incrustation
Authors: Boden Didier
Published: July 2022

Certaines règles prévoient que des dispositions édictées en dehors d’un État devront être considérées comme une composante du droit de cet État. Il ne s’agit pas de règles, dites d’incorporation, dont le droit constitutionnel de certains États impose l’adoption pour qu’un traité auquel ils deviennent parties doive être appliqué par leurs autorités. Ce ne sont pas non plus de ces normes que la tradition dénomme règles de conflit de droit international privé, désignant la loi applicable à certaines situations, ni des règles commandant la prise en considération d’une norme à l’occasion de l’application d’une autre norme. Il s’agit de dispositions auxquelles le présent article donne le nom de règles d’incrustation et dont il décrit la nature.
La dénaturation d’un élément de preuve du droit étranger au stade de l’instance en exequatur
Authors: Lenglart Elie
Published: July 2022

En raison de l’obligation pour le juge de ne pas dénaturer l’écrit qui lui est soumis, ne peut être rejetée la demande d’exequatur en France d’un jugement en énonçant que, pour l’obtenir, une décision étrangère doit être exécutoire dans son pays d’origine, la charge de la preuve incombant au demandeur, et en retenant que le demandeur avait échoué à rapporter la preuve que la décision est purgée de tout recours suspensif d’exécution au regard de la loi vanuataise, alors que, dans ses conclusions d’appel, le demandeur produisait un affidavit en vue d’établir, avec d’autres éléments de fait et de droit, que la décision dont l’exequatur était sollicitée avait un caractère exécutoire en vertu du droit vanuatais.
Le difficile maniement des critères d’applicabilité de la compétence de protection des consommateurs
Authors: Larribère Lilian
Published: July 2022

Manque de base légale l’arrêt qui refuse de déclarer applicable la protection des consommateurs des articles 15 §1 et 16 §1 de la Convention de Lugano II tout en retenant que certaines activités du professionnel sont dirigées vers le pays du domicile du consommateur s’il n’indique pas la nature de ces activités et les raisons pour lesquelles l’activité en cause n’entre pas dans leur domaine.
Holistic Admissions Review Integration in Nursing Programs
Authors: DeCoux Hampton Michelle , Dawkins Denise , Rickman Patrick Sheri , Onglengco Raissa , Stobbe Brenna , Kaufman Sarah , Alexa Hampton Chloe , Palazzo Claire
Published: July 2022

Background:

To address health inequities, the American Association of Colleges of Nursing, Institute of Medicine, and Association of American Medical Colleges recommend holistic admissions review (HAR) to increase health professional diversity.

Method:

This cross-sectional study collected admissions criteria from 1,547 nursing programs. Criteria were categorized according to the experiences, attributes, and academic metrics (EAM) model, and programs were dichotomized into those with holistic admissions criteria versus none.

Results:

Only 43% of nursing programs considered holistic admissions criteria. Regionally, rates varied from 35% in the South to 54% in the West. The rate of HAR integration exceeded 67% in only six states.

Conclusion:

Nursing programs have not widely integrated HAR despite evidence that academic metric use alone disadvantages qualified underrepresented students. HAR implementation can be facilitated by standardizing how HAR is operationalized and applying best evidence to rubric development that appropriately weighs admissions criteria based on the EAM model, and also training reviewers for unbiased candidate evaluation.

[
J Nurs Educ
. 2022;61(7):361–366.]
Nursing Students' Perceptions of Using Virtual Patients to Prepare for Clinical Practice
Authors: Chen Yanya , Li Zekai , Zou Xiaochun , Yang Qiaohong , Guan Bingsheng , Ming Wai-kit
Published: July 2022

Background:

Educators are called on to provide opportunities for students to practice and integrate skills and knowledge to ensure preparation for the complexities of today's health care environment. This study explored nursing students' perceptions of using virtual patients to prepare for clinical practice.

Method:

This study used an exploratory qualitative design. Four focus group interviews were conducted with 25 third-year nursing students. Data were collected and analyzed using thematic content analysis.

Results:

Four main themes and eight subthemes emerged. Main themes included personal engagement, learning environment, organizational factors, and improvement needed. Subthemes included being a computer game player, becoming confident in clinical practice, convenient to practice, an authentic stressful learning environment, organization, better to be combined with mannequin-based simulation, technology difficulties, and aural factors.

Conclusion:

Although some perceived disadvantages were identified, the use of virtual patients could be an effective strategy to improve nursing students' preparation for clinical preparation.

[
J Nurs Educ
. 2022;61(7):398–402.]
Defusing Land Mines: Keywords About Race in Nursing Education
Authors: Cahn Peter S.
Published: July 2022

Background:

The call for nurse educators to facilitate conversations about racism with learners has become inescapable. Yet, nurse educators in the United States indicate they feel unprepared or uncomfortable leading classroom conversations about race.

Method:

Keyword analysis maps the multiple meanings of vocabulary, creating a common foundation for productive dialogue. Selection of keywords is subjective, but each keyword must meet three criteria: a term that is in common use, definitions that change according to time and perspective, and use that illuminates larger phenomena.

Results:

Five keywords when teaching about racism are Caucasian, colorblind, diversity, reverse racism, and underrepresented minority. Each keyword carries connotations that may be perceived as upholding egalitarian ideals without acknowledging the pernicious mechanisms of racism itself.

Conclusion:

Familiarity with keywords provides educators with solid ground for engaging in often ambiguous and troubling dialogues about racism.

[
J Nurs Educ
. 2022;61(7):408–412.]
Educating APRN Students About Telehealth Credentialing, Licensing, and Billing
Authors: Chike-Harris Katherine , Snyder Elizabeth F. , Conner Ruth S.
Published: July 2022

Background:

An essential component of advanced practice nursing (APRN) education includes how to facilitate and adopt telehealth into practice, which includes becoming familiar with what is needed to practice telehealth and how to effectively bill for this service. This article describes the integration of telehealth credentialing, licensing, and billing into a preexisting APRN Role Practicum course.

Method:

Participants consisted of two cohorts (
n
= 129) of APRN students enrolled in a role preparation course within a Doctor of Nursing Practice curriculum. Students' knowledge and perceptions regarding the content of a prerecorded lecture were assessed using a pretest/posttest design. The posttest also included optional module assessment questions.

Results:

Student knowledge regarding the information presented increased, and overall student feedback was positive.

Conclusion:

Telehealth content was successfully integrated into a preexisting APRN Role Practicum course. Students found the information relevant to future practice and became knowledgeable regarding telehealth laws and regulations.

[
J Nurs Educ
. 2022;61(7):413–416.]
Viloxazine ER (Qelbree
®
): A New Non-Stimulant Option in the Treatment of Pediatric Attention-Deficit/Hyperactivity Disorder
Authors: Kameg Brayden
Published: July 2022

The current article provides a brief overview for psychiatric–mental health nurse practitioners of viloxazine extended-release (Qelbree
®
) for the treatment of pediatric attention-deficit/hyperactivity disorder. [
Journal of Psychosocial Nursing and Mental Health Services, 60
(7), 7–9.]
Changing Patterns of Pediatric Trauma During the COVID-19 Pandemic
Authors: Wieck Minna M. , Silva Taylor , Kohler Jonathan E.
Published: July 2022

The implementation of lockdown and social distancing policies at the beginning of the coronavirus disease 2019 (COVID-19) pandemic changed both the nature of pediatric traumatic injuries and how those injuries were managed by pediatric trauma centers. At the start of the pandemic, the number of injured children evaluated at trauma centers decreased. Trauma volumes have since rebounded, and a concerning increase in abuse-related injuries has been seen. Pediatric trauma systems responded to the pandemic with new approaches to protect health care providers, conserve critical resources, and assist adult trauma systems overburdened by patients with COVID-19. The widespread effect of COVID-19 continues to have significant repercussions on children's health, but the lessons learned and gaps exposed by the pandemic may be an opportunity to positively transform injury prevention and health care delivery.

[
Pediatr Ann
. 2022;51(7):e286–e290.]
Diarrhea in Resource-Rich Countries: Common and Uncommon Causes
Authors: Khan Leah
Published: July 2022

Diarrhea is a major cause of illness worldwide despite advancements in sanitation, hygiene, education, and awareness. In resource-rich countries, death is a rare complication, but the health care and economic burden remains. Guidelines have been developed by the Federation of International Societies of Pediatric Gastroenterology, Hepatology, and Nutrition Working Group as well as the Infectious Diseases Society of America to help with the diagnosis and management of acute infectious diarrhea (the most common underlying reason for diarrhea). There are also guidelines available for the evaluation and management of more chronic forms of diarrhea. If we follow these diagnostic approaches and recommendations for management, we should be able to achieve a balance of providing appropriate care to our patients without performing excessive and unnecessary diagnostic testing.

[
Pediatr Ann
. 2022;51(7):e260–e263.]
Mathematical analysis of tumor-free equilibrium in BCG treatment with effective IL-2 infusion for bladder cancer model
Authors: Volinsky Irina , Bunimovich-Mendrazitsky Svetlana
Published: July 2022

We present a theoretical study of bladder cancer treatment with Bacillus Calmette-Guerin (BCG) and interleukin 2 (IL-2) using a system biology approach to translate the treatment process into a mathematical model. We investigated the influence of IL-2 on effector cell proliferation, presented as a distributed feedback control in integral form. The variables in the system of Ordinary Differential Equations (ODE) are the main participants in the immune response after BCG instillations: BCG, immune cells, tumor cells infected with BCG, and non-infected with BCG. IL-2 was involved in the tumor-immune response without adding a new equation. We use the idea of reducing the system of integro-differential equations (IDE) to a system of ODE and examine the local stability analysis of the tumor-free equilibrium state of the model. A significant result of the model analysis is the requirements for the IL-2 dose and duration, depending on the treatment regimen and tumor growth. We proved that the BCG+IL-2 treatment protocol is more effective in this model, using the spectral radius method. Moreover, we introduced a parameter for individual control of IL-2 in each injection using the Cauchy matrix for the IDE system, and we obtained conditions under which this system would be exponentially stable in a tumor-free equilibrium.
Evaluación de la investigación científica: mejorando las políticas científicas en Latinoamérica
Authors: Arellano-Rojas Paulina , Calisto-Breiding Camila , Peña-Pallauta Paulina
Published: July 2022

Este artículo busca identificar criterios e indicadores de evaluación científica, que permitan mejorar la forma en que las agencias de financiación, las instituciones académicas y otros grupos evalúan la calidad e impacto de la investigación. Para ello, se realiza una revisión bibliográfica, basada en artículos sobre políticas de evaluación de la investigación científica y agendas internacionales implementadas en los últimos años (principalmente en el Reino Unido, Estados Unidos, Australia, China y Latinoamérica). Los resultados indican que no existe un solo método de evaluación científica, ya que ningún indicador es absoluto. Cada investigación posee actores distintos que deben ser considerados y se debe valorar la investigación en su contexto. Se recomienda un sistema de evaluación mixto, que incorpore criterios cuantitativos y cualitativos, pero que reconozca los límites y alcances de ambos y también de cada disciplina.
¿Qué hace que un tuit sobre un libro sea popular? Análisis de los contenidos más retuiteados creados por editoriales de libros españolas y extranjeras
Authors: Mas-Bleda Amalia , Makita Meiko , Mrva-Montoya Agata , Thelwall Mike
Published: July 2022

El objetivo de este artículo es identificar características relacionadas con el contenido de los mensajes más retuiteados creados por editoriales de libros españolas y extranjeras en Twitter. Se ha realizado un análisis de contenido para identificar el tema de los tuits y si incluyen hashtag para el título del libro, imágenes e hipervínculos, y en caso de incluirse, sobre qué son las imágenes y hacia dónde apuntan los enlaces. Como complemento, se ha realizado un análisis de asociación de palabras para identificar qué términos son asociados con cada una de las diferentes editoriales. En general, las editoriales tienden a tuitear sobre ellas mismas y sus libros con fines de marketing. Aproximadamente la mitad de las editoriales tienen cuentas en Twitter. Los tuits más populares de las editoriales españolas suelen contener citas literarias, mientras que los tuits más populares de las editoriales extranjeras tienden más a incluir sorteos. Los editores que buscan comprometerse con lectores potenciales en Twitter podrían considerar las citas y los sorteos para construir su audiencia, además de etiquetar al nombre de usuario del autor (@nombredeusuario) en tuits relacionados con libros para ayudar al autor con su red social.
El establecimiento de la misión de la Iglesia Libre de Escocia para la conversión de los judíos de Constantinopla en el s. XIX
Authors: Martín González Daniel
Published: July 2022

Investigaciones recientes han revelado la historia de la Junta Americana de Comisionados para las Misiones Extranjeras en el Imperio otomano en el s. XIX, escaseando la investigación de sus coetáneos escoceses en estas tierras. Este artículo explora la historia de la misión de la Iglesia Libre de Escocia establecida en Constantinopla tras el famoso cisma Kirk de 1843 con la Iglesia Nacional de Escocia. Este estudio presenta tanto el origen de las dos principales estaciones de esta iglesia, localizadas en Gálata y Hasköy, dedicadas a la conversión de los judíos de Constantinopla, principalmente sefardíes, así como también las estrategias de proselitismo de los misioneros y los resultados de su obra religiosa. Finalmente, este estudio nos presentará el alcance de la misión en cuanto al número de posibles conversiones y su recepción en la comunidad judía.
De pobladores a pobres. Representaciones documentales del colectivo Teleanálisis, durante la última fase de la dictadura militar en Chile
Authors: Capriles Francisco Núñez , Valdebenito Hernán Venegas
Published: July 2022

El artículo indaga sobre el colectivo Teleanálisis responsable de la serie documental del mismo nombre y la forma en que este esfuerzo cinematográfico representó a pobladores y pobladoras durante la contingencia de la movilización social y política que puso en jaque a la dictadura militar chilena entre 1984 y 1989. Como un correlato de los cambios de perspectiva respecto de la vía para derrotar a la dictadura, el sujeto poblador pasó, en la mirada de la serie, de un sujeto autónomo y central en la estrategia movilizadora, a un actor de segundo orden, sin agencia y subsumido en categorías sociales más amplias y sin especificidad.
La vida en los barrios obreros de la ‘República Independiente de San Miguel’. El caso de la población MADECO entre las décadas de 1940 y 1960
Authors: Flores Sebastián Leiva
Published: July 2022

Quienes han estudiado la identidad de la clase obrera chilena han relevado, mayoritariamente, la importancia del espacio y el tiempo del trabajo en su formación, proponiendo otros la influencia, en ese proceso, de los espacios donde esos trabajadores vivían. En esa dirección, en este artículo abordamos la historia de la población MADECO, de la industria homónima, donde sus trabajadores se relacionaron con diversos actores y participaron en variadas instancias, formando una identidad donde se observaba la influencia del sindicato, de la empresa y de los vecinos de las poblaciones colindantes, enriqueciendo y diversificando sus características y rasgos.
Letras obreras. Clase trabajadora y experiencia urbana en la escritura proletaria. Chile, primer cuarto del siglo XX
Authors: López Jorge Navarro
Published: July 2022

El artículo se propone estudiar la experiencia urbana de la clase obrera mediante el análisis de la narrativa que los/las trabajadoras produjeron y publicaron en la prensa obrera. Las letras obreras no sólo se abocaron a la política y a la ideología, debido a esto, permiten conocer las proyecciones, valores y visiones sobre la experiencia del proletariado urbano. A través del análisis de la producción poética y narrativa proletaria, se propone profundizar en la cotidianidad, los significados, la imaginación, las preferencias estéticas y el modo de vida popular, dimensiones fundamentales de la cultura obrera del primer cuarto del siglo XX.
El viaje urbano en tranvía como práctica (re)creativa en evocaciones literarias de voces masculinas
Authors: Prudant Elisabet
Published: July 2022

El viaje en transporte público ha sido poco estudiado desde una perspectiva histórica que considere sus posibilidades como práctica cultural, imponiéndose la idea de que se trata apenas de un ejercicio repetitivo de desplazamiento funcional. Esta aproximación puede ser revisada en la medida que el análisis histórico en sus cruces con la literatura permite identificar otras formas de dar sentido al recorrido urbano a partir de los procesos identitarios del género. El artículo analiza evocaciones literarias de voces masculinas sobre el viaje en tranvía, el más significativo de los medios de locomoción pública en Santiago de Chile durante el periodo que va entre fines del siglo XIX y las primeras décadas del XX. Se trata de añoranzas de niñez y juventud que dan cuenta de las prerrogativas de los cuerpos de varones pertenecientes a estratos medios y altos en su vivencia de desplazamiento cotidiano como instancia de esparcimiento y creación artística. Se indagará en dos dimensiones en lo que refiere al uso “para sí” del viaje colectivo masculino: la lúdica y la exploratoria.
“Una inmensa cloaca de infección y de vicio”: Santiago popular y distopía en la historiografía y la novela chilena 1880-1900
Authors: Sotoconil Araucaria Rojas
Published: July 2022

El presente texto tiene por objeto primordial dar cuenta de cómo se representa el Santiago popular en la historiografía y la novela chilena, producidas entre 1880 y 1900. En primer lugar, se pretende dar contestación a la pregunta ¿quién habita la ciudad popular?, para luego indagar en la descripción distópica del espacio. En ambos corpus se presta particular atención a la chingana, como epítome de un pueblo bullicioso y desenfrenado. Se propone asimismo, que las características arrogadas a la ciudad popular son las mismas que se utilizan para definir al pueblo: el territorio encarna el exceso y la precariedad de quienes lo habitan.
La bière à la Protohistoire. L’exemple des grands contenants champenois
Authors: Saurel Marion
Published: July 2022

La relation forte unissant grands contenants et boissons fermentées, attestée par de nombreuses sources ethnographiques et archéologiques, incite à porter une attention particulière aux céramiques de grande capacité découvertes dans les habitats protohistoriques. L’intérêt d’approfondir ce sujet est conforté par l’étude fonctionnelle de corpus domestiques de l’âge du Fer en Champagne qui met en évidence des tendances morphologiques, une relation entre pâtes et traces d’altération intérieure potentiellement dues à l’action de contenus acides/fermentés, ainsi que des contextes prometteurs impliquant de grandes céramiques. Sur ces fondements, un projet collectif se met en place visant à approfondir l’analyse des grands contenants en précisant les critères et l’approche fonctionnelle à chacune de ses étapes – définition souple de familles de récipients, étude des pâtes, quantification des traces, remise en contexte à différentes échelles – afin d’apporter une contribution renouvelée à la compréhension des formes de la production et de la consommation des alcools au cours de la Protohistoire.
Vestiges du divin, commencements de l’humain : l’évolution du débat sur les hiéroglyphes de la Renaissance à Champollion
Authors: Graczyk Annette
Published: July 2022

L’article explore les implications mystiques, hermétiques et platoniciennes du discours hiéroglyphique et sa compréhension emblématique depuis la Renaissance. L’approche de Kircher est replacée dans ce contexte. Elle fut rejetée par les spécialistes du xviiie siècle et plus encore après les travaux de Champollion, et la poursuite de la compréhension des hiéroglyphes s’est développée sur la base des conceptions de Vico, Warburton et Herder. Elle faisait désormais autant référence à des caractères non égyptiens qu’à des signes bibliques. L’hypothèse religieuse selon laquelle les hiéroglyphes étaient d’origine divine fut progressivement remise en question, ce qui conduisit à leur désenchantement par la science.
Psychosocial, Economic and Environmental Impact of COVID-19: Risks and Rewards
Authors: Menike W.A.R.P.
Published: July 2022

Background and Objective: Two thousand twenty was a significant year for the world, changing drastically every aspect of human life within a short period of time due to the outbreak of COVID-19. The pandemic affected human beings physically, psychologically as well as and socioeconomically. A noticeable reduction of environmental pollution and climate changes were reported during the worldwide lockdown in response to COVID-19 pandemic. In January 2020, the World Health Organization (WHO) declared the outbreak of COVID-19 as a public health emergency. In spite of the panic created globally, the positive and negative elements resulting in risks and rewards have been discussed extensively. This narrative synthesis further presents suggestions to reorganize the social systems to save the earth during pandemic.Methods: A thorough literature search was carried out during December 2019 – January 2021 period, using the PubMed, Researchgate and Google Scholar. Findings were presented as a narrative synthesis.Results: Findings report a noticeable reward of COVID-19 including the positive impact of family life, in terms of improving inter-family relationships, climate changes such as reduction of environmental pollution, carbon emissions and energy use. Negative aspects include the economic crisis and financial risks caused by restrictions such as lockdown measures.Conclusions: The COVID-19 has immediate positive effects on the environment while there are negative effects on economic aspects.
Pityriasis rosea and pityriasis rosea-like eruption after anti-SARS-CoV-2 vaccination: a report of five cases and review of the literature
Authors: Veraldi Stefano , Boneschi Vinicio , Cusini Marco , Maronese Carlo Alberto
Published: July 2022

Only some cases of pityriasis rosea (PR)/pityriasis rosea-like eruption (PRLE) after anti-SARS-CoV-2 vaccination have been reported. In the period May 2021 - February 2022 we observed five cases of clinically typical PR that appeared 2 to 3 weeks after anti-SARS-CoV-2 vaccination with BNT162b2 (3 patients) or mRNA-1273 (2 patients). In four patients PR appeared after the first vaccination; in one patient after the second one. In three patients a biopsy for histopathological examinations was carried out. Results were typical for PR. In all patients laboratory examinations were within normal ranges. All patients were treated with cetirizine. Complete remission was observed within 14-30 days. Four patients were subjected to the second vaccination, but no skin lesions appeared. All patients are currently in good general health. It is possible that a relationship anti-Sars-CoV-2 vaccination−PR/PRLE exists; however, it is very rare, in consideration of millions of vaccinated subjects and the low number of reported cases of PR/PRLE. The pathogenesis of this relationship is unknown. However, some hypotheses may be advanced: PR/PRLE following anti-Sars-CoV-2 vaccination may be just a coincidence; anti-Sars-CoV-2 vaccines cause a reactivation of HHV-6 and/or HHV-7; vaccines can induce a delayed hypersensitivity response clinically similar to drug-induced PRLE.
Comparative Assessment of the Implementation of Integrated Disease Surveillance and Response in Public and Private Health Facilities in Jos North Local Government Area of Plateau State, Nigeria
Authors: Tagurum Yetunde Olubusayo , Dogo M. Joy , Adah G. A. , Maimagani I. C , Sodipo O. O. , Adeniji T. , Daboer J. C. , Banwat M. E. , Lar L. A. , Akosu T. J. , Chingle M. P.
Published: July 2022

Background:

Due to the continuous increase in the spread of epidemic-prone diseases and the associated morbidity and mortality, integrated disease surveillance and response (IDSR) was introduced as the main strategy in resource-poor settings for the detection and notification of these diseases. Integrated disease surveillance is a combination of active and passive systems using a single infrastructure that gathers information about multiple diseases or behaviors of interest.

Methods:

A comparative cross-sectional study was conducted between March and July 2018 among selected public and private health facilities in Jos North Local Government Area (LGA), Plateau State. Quantitative data were collected with the aid of a semi-structured interviewer-administered questionnaire and facility-based checklist. Data were analyzed using SPSS version 23. Statistical significance level was set at P ≤ 0.05 at a 95% confidence level.

Results:

A total of 126 health workers were studied. IDSR-trained health personnel was found in 52.7% of the public health facilities compared with only 16.7% of the private health facilities studied (P < 0.001). Awareness of IDSR was higher in the public health facilities than in the private ones (P < 0.001). IDSR implementation was poorer in the private health facilities 40.7% compared with 76.4% in public health facilities (P < 0.001). Evidence of previous disease notification and reporting was seen only in 33.3% and 16.7% of public and private health facilities, respectively (P < 0.001).

Conclusion:

This study revealed that awareness and attitude of health workers in public health facilities in Jos North were higher than that of those in private health facilities and there is the sub-optimal implementation of IDSR among the health workers in Jos North LGA, especially among the private health facilities.
Effect of Vitamin Supplementation in Patients of Congestive Heart Failure Deficient in Vitamin D
Authors: Mohanty Vivek , Pathania Monika , Bhasi Ankith
Published: July 2022

Introduction:

Heart Failure is a leading cause of mortality worldwide including India. Most cross sectional studies have demonstrated heart failure is associated with deficiency of essential micronutrients including Vitamin D which may play a important role in pathogenesis of ventricular remodelling in heart failure.

Aim:

Our study performed aimed to determine the effect of supplementation in patients of Heart Failure presenting with Vitamin D deficiency to our institute on severity of Heart Failure.

Design and Method:

97 patients of Heart failure coming to our institute were given conventional therapies for Heart Failure along with Vitamin supplementation based on serum Vitamin D levels and followed up for 3 months.

Results:

Patient of Heart failure having Vitamin D deficiency had significant reduction in cardiac biomarkers (NT-pro BNP levels), improvement in Left ventricular ejection fraction (LVEF) and more favourable reverse remodelling determined by Left ventricular end diastolic and systolic diameter (LVEDD & LVESD) though quality of life determined by WHODAS 2.0 score did not changed following 12 weeks supplementation of High Dose Vitamin D.

Conclusion:

Recognising and treatment of Vitamin D deficiency may determine long term prognosis in patients of Heart Failure.
Neonatal Outcome of Twins and Singleton Neonates
Authors: Meshram Rajkumar Motiram , James Arya
Published: July 2022

Introduction:

It is impossible to achieve the target of Sustainable Developmental Goal without focusing on care of twins' neonates as they are more prone for death and higher chance of long-term morbidity and neurodevelopmental handicap in survivors.

Aim:

To estimate the outcome among twin and singleton neonates at a tertiary care teaching center of Eastern Maharashtra.

Materials and Methods:

Prospective observational study was conducted on neonatal intensive care unit graduates of twin birth and simultaneously admitted singletons at Government Medical College and Hospital Nagpur from June 2020 to February 2021 (9 months). Outcome among twin and singleton neonates, and their morbidity and mortality pattern were studied.

Results:

A total of 210 neonates of twin birth and 870 singleton neonates were recruited. Male were dominant in both groups. Preterm and low birth weight neonates were significantly more in twins compared to singleton neonates. Twin neonates were significantly more hypothermic (P < 0.001) and hypoxic (P = 0.001) compared to singleton. Jaundice (37.62%) and respiratory distress syndrome (36.67%) were the most common diagnosis in twin neonates while sepsis (34.71%) was predominant in singleton. Sepsis (33.9%) was the most common cause of death in singleton neonates while respiratory distress syndrome (35.38%) in twin births. Length of hospital stay (P < 0.0001) and neonatal mortality were significantly higher in twin neonates compared to singleton neonates (P = 0.001).

Conclusion:

Sepsis is the leading cause of admission and death in singleton neonates while respiratory distress syndrome in twins. Twin neonates have significantly higher mortality and longer hospital stay because of prematurity and low birth weight.