bluuebunny/crossref_metadata_2025 huggingface dataset:
Understanding Colourism in Malaysia Through Discursive Constructions of Skin Colour on Social Media
Authors:   Independent Researcher, Pulau Pinang, Malaysia, Zulkifli Zulfati Izazi
Published: May 2024

Colourism refers to any act of discrimination that is portrayed on the basis of skin colour or the act of attributing negativity upon dark skin. This article explores the extent to which colourism prevails in Malaysia by studying the discourse of skin colour on social media. The data is gathered from Twitter (now known as X), a social media platform that allows users to interact with short messages called “tweets”. The tweets are sourced from the Malaysian Twitter diaspora via the keyword “kulit gelap”—a phrase in Malay language which translates to dark skin. The analysis is conducted in alignment with the viewpoint of discourse-historical approach, where a qualitative analysis is employed to examine the linguistic devices and discursive strategies utilised to construct the notion of dark skin. The results indicate that dark skin is often portrayed in a negative light, suggesting that colourism is pervasive in language use. Through the analysis, several discursive strategies are identified, such as nomination of dark skin as a problem and stereotypical predication of dark skin.
Multicomponent Reactions in the Last 30 Years: How are we Today?
Authors: de Lima Henrique , das Neves Gustavo , Gonçalves Itamar , Merlo Aloir , Eifler-Lima Vera
Published: May 2024

In this review, the works carried out in Brazil with multicomponent reactions over a period of 30 years were mapped through search in the literature (PubMed, Scopus, and Web of Science). A significant increase in papers with multicomponent reactions in Brazil was identified. In total, 243 articles with 6,672 citations (average of 27.46 citations per article) were found. Biginelli, Ugi, Mannich, Passerini and Hantzsch are the most employed reactions, and the articles were classified in medicinal chemistry, catalyst, mechanism, green chemistry, asymmetric synthesis and fluorescent. A bibliometric analysis with the 243 articles was performed, including the number of publications, citations, predominant journals, Brazilian universities with the highest number of publications on the subject, and international collaborations.
Characteristics of convergence and stability of some methods for inverting the Laplace transform
Authors:   St. Petersburg State University, Lebedeva Anastasia V. , Ryabov Victor M. ,   St. Petersburg State University
Published: May 2024

The problem of inversion of the integral Laplace transform, which belongs to the class of ill-posed problems, is considered. Integral equations are reduced to ill-conditioned systems of linear algebraic equations, in which the unknowns are either the coefficients of the series expansion in terms of special functions, or the approximate values of the desired original at a number of points. Various inversion methods are considered and their characteristics of accuracy and stability are indicated, which must be known when choosing an inversion method for solving applied problems. Quadrature inversion formulas are constructed, which are adapted for the inversion of long-term and slow processes of linear viscoelasticity. A method of deformation of the integration contour in the Riemann-Mellin inversion formula is proposed, which leads the problem to the calculation of certain integrals and allows obtaining error estimates.
Między powinnościami i społecznymi uwikłaniami. Analiza mediów w serialu Ranczo
Authors: Szydłowska Magdalena , Szczepańska Paulina
Published: May 2024

Artykuł koncentruje się na analizie mediów przedstawionych w produkcji telewizyjnej – w serialu Ranczo. Serial, który nosi znamiona swoistego mechanizmu samoopisu kultury, określa się mianem „polskiej produkcji wszechczasów”. Analizie poddano kolejno lokalną prasę, radio i telewizję. Przybliżono ich rozwój i charakter. Zwrócono także uwagę na ich rolę w życiu społeczności lokalnej. Wyjaśnione zostały także podstawowe pojęcia, niezbędne przy tego typu analizie.
Identification of Molecular Subtypes Associated with PCD in
Esophageal Squamous Cell Carcinoma and Analysis of Immune
Microenvironment
Authors: Chen Min , Qi Yijun , Zhang Shenghua , Du Yubo , Cheng Haodong , Gao Shegan
Published: May 2024

Background::

Esophageal squamous cell carcinoma (ESCC) is a highly fatal
malignancy with increasing incidence, and programmed cell death (PCD) plays an important
role in homeostasis.

Aims::

This study aimed to explore the ESCC of heterogeneity based on the PCD signatures
for the diagnosis and treatment of patients.

Methods:

The clinical information and RNA-seq data of patients with ESCC and the
PCD-related genes set were used to identify PCD signatures.The “limma” package was
used to identify the differentially expressed genes (DEGs). “Clusterprofiler” package
was used for function enrichment analysis, and the “ConsensusClusterPlus” package
was performed for consensus clustering. Finally, the “GSVA” package and the Cibersort
algorithm were used for the immune infiltration analysis.

Results::

We performed differential expression analysis between ESCC and normal samples
and identified 1659 DEGs, of which 124 DEGs were PCD genes. Then, the patients
were divided into cluster1 and cluster2 based on the expression of 124 PCD genes.
There was a significant difference in immune infiltration between the two clusters. The
patients in cluster 1 had a higher immune score and more CD56dim natural killer cells,
monocytes, activated CD4 T cells, eosinophil, and activated B cells infiltration, while
cluster2 had a higher stromal score, more immune regulation, and immune checkpoint
genes expression.

Conclusion::

We identified two clusters based on PCD gene expression and characterized
their tumor microenvironment and immune checkpoint difference. Our findings
may provide some new insight into the treatment of ESCC.
Personalized Approaches to Cardiovascular Disease: Insights into
FDA-Approved Interventions and Clinical Pharmacogenetics
Authors: Raoufinia Ramin , Rahimi Hamid Reza , Abbaszadeh Mahla , Gholoobi Aida , Saburi Ehsan , Fakoor Farhad , Alshakarchi Hawraa Ibrahim , Gataa Ibrahim Saeed , Hassanian Seyed Mahdi , Ferns Gordon A. , Khazaei Majid , Avan Amir
Published: May 2024

Cardiovascular diseases place a considerable burden on global health systems, contributing to high
rates of morbidity and mortality. Current approaches to detecting and treating Cardiovascular Diseases (CVD)
often focus on symptomatic management and are initiated after the disease has progressed. Personalized
medicine, which tailors medical interventions to individual characteristics, has emerged as a promising strategy
for improving cardiovascular health outcomes. This article provides an overview of personalized medicine
in the context of CVD, with a specific emphasis on FDA-approved interventions. It explores the potential benefits,
challenges, and future directions of personalized medicine in cardiovascular disorders. By reviewing the
advancements in this field, this article underscores the importance of early detection, intervention, and innovative
treatment options in reducing the impact of CVD on individuals and society.
Nano Encapsulation of An Essential Oil Transpire the Therapeutic
Approach
Authors: Chhetri Sukanya , Arora Shefali , Parcha Versha , Kumar Deepak , Rawat Devendra Singh
Published: May 2024

Essential oils are natural compounds extracted from plants that are volatile and sensitive to heat. Due to their therapeutic value, essential oils are now used in many industries, including the sanitary, cosmetic, agricultural, food, and pharmaceutical industries. These are complex mixtures of a wide range of volatile molecules, including phenol-derived aliphatic and aromatic compounds and terpenoids. Essential oils have been used medicinally since ancient times
for their antibacterial, antifungal, antiviral, antiparasitic, insecticidal, sedative, antiinflammatory, and anaesthetic properties. However, essential oils come with inherent limitations; thus, nanoencapsulation is advocated as a remedy as it has the potential to enhance the
stability, solubility, and effectiveness of formulations based on essential oils, all while preserving the therapeutic drug blood levels. It is not always viable to use essential oils independently
in treatment due to several restrictions; however, nanodelivery technologies appear capable of
overcoming these challenges. The therapeutic efficacy that is achieved can be affected by several factors, including the selection of the essential oil as well as the system of nanodelivery. Today, nanoencapsulation is capable of enabling the simultaneous delivery of multiple oils, providing synergistic effects, and facilitating the development of combinational therapies. Additionally, they may have potential applications in preserving food to prolong the shelf life of quickspoiling items and their fragrances. While there is already much research on the characterisation
of EOs, this review evaluates the features of the nanoparticles employed for the delivery of essential oils and their impact on the functionality of nano-delivered essential oils and their beneficial uses.
Mechanical Design of Variable Stiffness Joint Based on Planetary Gear Train and Modular Elastic Element
Authors: Guo Jishu
Published: May 2024

Background::

The variable stiffness joint (VSJ) is a kind of inherent flexible actuator
with independent controllable position and stiffness. Among various types of VSJs, the VSJs based
on equivalent lever mechanisms and relying on changing the position of the lever pivot to adjust the
transmission rate between input and output have the characteristic of low energy consumption for
stiffness adjustment. Therefore, many patents have been applied for this type of VSJ. As the structural
design of VSJs is an open research field, it is necessary and meaningful to explore novel structural
designs of VSJs based on equivalent lever mechanisms.

Objective::

The purpose of this article is to design a variable stiffness joint that changes the joint
stiffness by adjusting the position of the lever pivot.

Methods::

By referring and combining existing mechanical design ideas of some series configuration
VSJs with good stiffness adjustment mechanism schemes, a novel series configuration VSJ
based on an equivalent lever mechanism and relying on adjusting the position of the lever pivot to
change joint stiffness has been implemented through CAD drawing, 3D printing, and assembly.

Results::

Due to the wide movable range of the lever pivot, the designed VSJ has a wide adjustable
range of stiffness. Moreover, assembly design and modular design have been achieved in terms of
elastic output and power transmission, for easy installation and maintenance. The movability and
stiffness adjustability of the designed VSJ were preliminarily verified through manual adjustment.

Conclusion::

The assembly model of the VSJ demonstrates the feasibility of structural design. The
stiffness adjustment experiment showed the variable stiffness ability of the designed VSJ.
The Effect of Load Steps and Initial Crack Length on Stress Distribution of Fiber Metal Laminates
Authors: Anam Khairul , Purnowidodo Anindito , Ananta Bonang , Kumar Pavan Kumar Asur Vijaya
Published: May 2024

Fiber Metal Laminates (FMLs) are advanced composite materials composed of alternating layers of fiber-reinforced composites and metal sheets, offering a unique blend of high strength, stiffness, and fatigue resistance. Understanding the behavior of FMLs under different loading conditions, particularly in the presence of initial cracks, is crucial for predicting their structural integrity and performance. This study investigates the effect of initial crack length and load steps on the stress distribution within FML structures through numerical simulation. A glass fiber-reinforced epoxy (GFRE) composite is constituted by glass fibers in off-axis directions of 0o/90o. The crack length of 3 mm, 6 mm, 9 mm, and 12 mm is initially defined on the side of fiber metal laminates. The tensile load was gradually applied to the laminates for five different ratios. The ratios are defined by dividing the tensile load with the area of the laminates which is then called stress ratio. The results show that the greater the initial crack length and load step ratio, the greater the stress around the crack tip. The stress distribution in each layer of the laminates shows different characteristics between tensile and compressive. This will affect the crack propagation behavior of the laminates. Moreover, the findings also provide valuable insights for optimizing FML design, improving damage tolerance, and extending service life in diverse engineering applications.
Analysis of The Corrosion Inhibition Efficacy of Camellia Sinensis Extract on Aluminium 6061 Alloys using Artificial Neural Network (ANN)
Authors: Andrean Janu , Harmayanti Afifah , Wahjudi Ari , Syamlan Adlina
Published: May 2024

Aluminum alloys, well known for their corrosion resistance, could encounter corrosion issues in acidic environments. These environments induced pitting and exfoliation corrosion due to the absence of oxide layers from such alloys. Camellia sinensis extract, one of the organic extract, had inhibition compounds, including tannins and cathecins, that could inhibit corrosion and reduce the corrosion rate. Hence, this study investigated the corrosion inhibition efficacy of Camellia sinensis extract on Aluminum 6061 alloys when exposed to an acidic environment (1M HCl). Different concentrations of the extract were prepared to obtain the optimum concentration and achieve the highest inhibitor efficiency. In addition, an artificial neural network (ANN) model, was employed to predict polarization current in both inhibited and unhibited solutions. The model was designed using a configuration of one input, six hidden and one output ;ayers. The study discovered that the efficiency reached a remarkable level of 82.68% when using a concentration of 3000 ppm of Camellia sinensis extract. Furthermore, the ANN model demonstrated excellent performance in predicting polarization current across all variations, with determinant coefficient (R2) values of 0.995 for 0 ppm, 0.990 for 1000 ppm, 0.997 for 2000 ppm, 0.9996 for 3000 ppm, and 0.996 for 4000 ppm. These results indicated that the model was reliable in simulating the electrochemical analysis of corrosion behavior which could be used to develop a corrosion rate predictor in the future.
Respon Pembungaan dan Hasil Beberapa Aksesi Stroberi (Fragaria sp.) Terhadap Variasi Lingkungan Fotoperiode
Authors: Rosyadi Naufal Luthfi , Andrini Anis , Ashari Sumeru
Published: May 2024

Kebutuhan buah stroberi (Fragaria sp.) dalam negeri masih dipenuhi oleh impor dari negara penghasil stroberi. Produksi stroberi di Indonesia pada tahun 2018 sebesar 85.285 ton, kemudian pada tahun 2019 mengalami penurunan menjadi 74.990 ton. Produksi buah stroberi bergantung pada proses pembentukan bunga yang dipengaruhi oleh suhu dan fotoperiode. Penelitian ini bertujuan untuk mengetahui respon pembungaan dan hasil stroberi pada beberapa lingkungan fotoperiode serta menyeleksi aksesi stroberi yang potensial. Penelitian ini dilaksanakan pada bulan September hingga November 2022 di kebun penelitian stroberi milik Balai Standardisasi Instrumen Pertanian yang berlokasi di Jl. Raya Tlekung No. 1, Junrejo, Batu. Penelitian disusun dalam percobaan yang dirancang pada 3 lingkungan fotoperiode, yaitu F1: fotoperiodisitas normal (kontrol), F2: fotoperiodisitas 8 jam (short day), dan F3: fotoperiodisitas 16 jam (long day). Rancangan yang digunakan dalam setiap lingkungan percobaan adalah Rancangan Acak Kelompok (RAK) dengan perlakuan 7 aksesi stroberi. Setiap plot lingkungan percobaan diulang sebanyak 3 kali. Variabel yang diamati berupa variabel vegetatif, generatif, dan hasil panen. Hasil penelitian menunjukkan bahwa fotoperiode mempengaruhi panjang fase vegetatif tanaman stroberi sehingga dapat menghambat pembungaan tanaman stroberi. Aksesi ICS04050036 (A2), Knia (A3), dan ICSP04050016 (A5) berbunga
Estimated Cost of Power Losses Due to Imbalance, No-Load and On-Load on Transformers in 2023-2033
Authors: Liliana Liliana , Aini Zulfatri , Bandri Sepannur
Published: May 2024

The greater the power losses, the higher the loss costs for the transformer. These losses can occur due to load, no-load, and load imbalance factors. This study aims to obtain the cost of losses incurred due to these three factors for ten years (2023-2033). The estimated cost of losses due to unbalance is obtained from the calculation of power losses in the neutral of the transformer, the cost of no-load losses is obtained from the losses of the iron core in the transformer, In contrast the cost of load losses is influenced by the development of the load and the interest rate for each year. As a result, the greatest power losses occur under unbalanced conditions with an average load for ten years of 88.68%, followed by no-load conditions of 11.10% and 0.21% load. The total power losses for ten years amounted to Rp. 3,029,196,416.64.
IoT-based Pregnant Mother Contraction Monitoring System Design
Authors: Romadhoni Sahrul , Sulistiyowati Indah , Rizqiyah Mar’ati Amalia
Published: May 2024

Pregnancy is an important stage in a woman's life that requires special monitoring and care to ensure the well-being of both mother and fetus. The presence of uterine contractions is an im-portant indicator of imminent labour, and prompt monitoring is essential to spot difficulties and ensure a safe delivery. This study aims to track contractions in pregnant women to improve pre-natal and labour care. Real-time monitoring, recording and analysis of uterine contractions. This research is a type of RD research with the ADDIE model (Analysis, Design, Development, Implementation, and Evaluation. The result of this tool is that it can precisely track contraction activity and send information to the IoT network. Through an easy-to-use mobile app, this in-formation can be accessed by medical staff caring for pregnant women and pregnant women themselves. To provide continuous monitoring, provide early notification of alarming changes, and facilitate rapid medical response, this monitoring system utilizes IoT technology. This can ease the burden on medical institutions, lower the possibility of difficulties during labour, and provide a sense of security for pregnant women. As an innovative and effective tool, the Inter-net of Things-based Maternal Contraction Monitoring System is anticipated to improve prenatal and delivery healthcare, reduce maternal and infant mortality, and monitor contractions in preg-nant women. The healthcare of pregnant women around the world could be significantly im-proved with the successful implementation of this approach.
Ad Hoc Modifications to a High Dependency Psychiatric Unit for People With Dementia During the COVID-19 Period
Authors: Pilunthanakul Thanita , Tan Giles Ming Yee
Published: May 2024

The COVID-19 pandemic led to behavioral exacerbations in people with dementia. Increased hospitalizations and lack of bed availability in specialized dementia wards at a tertiary psychiatric hospital in Singapore resulted in lodging people with dementia in the High Dependency Psychiatric Unit (HDPCU). Customizations to create a dementia-friendly environment at the HDPCU included: (1) environmental modifications to facilitate orientation and engender familiarity; (2) person-centered care to promote attachment, inclusion, identity, occupation, and comfort; (3) risk management for delirium; and (4) training core competencies. Such practical solutions can also be implemented elsewhere to help overcome resource constraints and repurpose services to accommodate increasing populations of people living with dementia.
Suitability of the Current Health Technology Assessment of Innovative Artificial Intelligence-Based Medical Devices: Scoping Literature Review
Authors: Farah Line , Borget Isabelle , Martelli Nicolas , Vallee Alexandre
Published: May 2024

Background

Artificial intelligence (AI)–based medical devices have garnered attention due to their ability to revolutionize medicine. Their health technology assessment framework is lacking.

Objective

This study aims to analyze the suitability of each health technology assessment (HTA) domain for the assessment of AI-based medical devices.

Methods

We conducted a scoping literature review following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) methodology. We searched databases (PubMed, Embase, and Cochrane Library), gray literature, and HTA agency websites.

Results

A total of 10.1% (78/775) of the references were included. Data quality and integration are vital aspects to consider when describing and assessing the technical characteristics of AI-based medical devices during an HTA process. When it comes to implementing specialized HTA for AI-based medical devices, several practical challenges and potential barriers could be highlighted and should be taken into account (AI technological evolution timeline, data requirements, complexity and transparency, clinical validation and safety requirements, regulatory and ethical considerations, and economic evaluation).

Conclusions

The adaptation of the HTA process through a methodological framework for AI-based medical devices enhances the comparability of results across different evaluations and jurisdictions. By defining the necessary expertise, the framework supports the development of a skilled workforce capable of conducting robust and reliable HTAs of AI-based medical devices. A comprehensive adapted HTA framework for AI-based medical devices can provide valuable insights into the effectiveness, cost-effectiveness, and societal impact of AI-based medical devices, guiding their responsible implementation and maximizing their benefits for patients and health care systems.
Community Empowerment Through Bamboo Laminate Technology as Part of Disaster Conservation and Mitigation in Wonokerto, Turi, Sleman, Yogyakarta
Authors: Krisdiyanto Didik , Farihah Tutik , Supriyati Hikmah
Published: May 2024

Bamboo is included in the classification of grasses, but because of its large size compared to other types of grass, bamboo is also called "giant grass". Bamboo has the ability to grow fast which reaches 30-100 cm per day. The target that is the focus of this service is the empowerment of the DIY SAR Team in Wonokerto to become a transfer agent for laminated bamboo technology through the training provided. The approach taken in community service is based on research that has been carried out in universities (Research base community development) by involving potential communities in the community (community based) as social agents and based on assets or potential (assessed base community development) in the community at the same time. support the government's program to realize Merapi as a National Strategic Area (KSN). Based on the overall implementation and analysis of the successful understanding survey, it can be seen that 60% of respondents can correctly answer questions regarding the definition of the stages of technology application, definition of interest, definition of natural resources, definition of product modification, things needed in bamboo laminate.Bamboo is included in the classification of grasses, but because of its large size compared to other types of grass, bamboo is also called "giant grass". Bamboo has the ability to grow fast which reaches 30-100 cm per day. The target that is the focus of this service is the empowerment of the DIY SAR Team in Wonokerto to become a transfer agent for laminated bamboo technology through the training provided. The approach taken in community service is based on research that has been carried out in universities (Research base community development) by involving potential communities in the community (community based) as social agents and based on assets or potential (assessed base community development) in the community at the same time. support the government's program to realize Merapi as a National Strategic Area (KSN). Based on the overall implementation and analysis of the successful understanding survey, it can be seen that 60% of respondents can correctly answer questions regarding the definition of the stages of technology application, definition of interest, definition of natural resources, definition of product modification, things needed in bamboo laminate.
Mask-Wearing Behavior Among Individuals Newly Diagnosed With Type 2 Diabetes: Insights From Community Health Screenings During the COVID-19 Pandemic in Indonesia
Authors: Yokota Fumihiko , Anai Akane
Published: May 2024

The coronavirus disease 2019 (COVID-19) pandemic has had a severe impact on people with type 2 diabete (T2D) and their health behaviors. This study investigated the associations between T2D status and mask-wearing behaviors in public settings during the first wave of COVID-19 among community residents in Yogyakarta, Indonesia. Outreach health checkups and self-report questionnaires were cross-sectionally conducted to measure for mask-wearing behavior, T2D status, and sociodemographic characteristics. Chi-square tests, bivariate, and multivariate logistic regression were performed for data analysis. Out of 254 total participants, nearly one forth (24%) of them were newly diagnosed with T2D, while 15% of them reported that they had ever been diagnosed as T2D before. There were no statistically significant associations between mask-wearing behavior and T2D status in bivariate and multivariate logistic regression models. However, Chi-square test results showed significant differences (P=0.02) in percentages of inconsistent mask-wearing behavior among those who were newly diagnosed as T2D (19.4%), those who had known as T2D (7.9%), and those who had no T2D (7.1%). This discrepancy in the results suggests the need for further investigations using larger sample size and more representative community samples to examine the associations between mask-wearing behaviors and T2D. Early diagnostic services and the awareness education for T2D is imperative to reduce the disease severity and mortality for future pandemic particularly among undiagnosed individuals who are unaware of their T2D status,
The Importance of Using Maternal and Child Health Books to Monitor Children’s Growth and Development: A Health Education Program
Authors: Tanjung Ika Citra Dewi , Pratita Winra , Martineta Meriza
Published: May 2024

Children differ from adults in the fact that they go through a continuous process of growth and development. Every parent hopes that their child can grow and develop optimally. To assess these expectations, regular monitoring is required. One of many ways to achieve this is the use of the Mother and Child Health (MHC) book published by the Indonesian Ministry of Health. This book contains complete information about maternal and child health and can be read by parents. In the current study, efforts to increase the use of MCH books were carried out offline by providing education to parents and health workers, and by assessing the extent to which MCH books had been completed. The education session was attended by about 100 parents and health workers, and the MCH book assessment was attended by 41 mothers with toddlers. Of these, 10 did not have an MCH book, while 18 out of the remaining 31 showed a low level of completion. The sections that were most often filled in were the health cards growth and immunization charts. During the assessment, the implementing team also invited parents to complete the MCH book so that their child's growth and development could be better documented. Health workers are expected to fill out the MCH book when toddlers are brought to health facilities, whether they are healthy or sick. This community service program can increase the ability of parents and health workers to use and complete the MCH books in order to monitor children's growth and development.
An Improvement of Livestock Feed Quality Through the Production of Fermented Complete Feed in the Karya Manunggal Livestock Group, Donokerto, Turi, Sleman, Yogyakarta
Authors: Anam Moh Sofi'ul , Baskara Aji Praba , Agus Ali , Setyawan Erif Maha Nugraha , Akhda Najmu Tsaqib
Published: May 2024

This community service aimed to assist farmers in improving their knowledge and quality of feed by producing fermented complete feed (FCF). The community service occurred from June to November 2019 in the Karya Manunggal livestock group in Donokerto, Turi, Sleman. The activities included observing the initial conditions of the group, providing counseling, conducting FCF production training, evaluating the products, and utilizing the trained products for the livestock. The results of the activities indicated an increase in farmers' knowledge about manufacturing concentrate and feed supplements, feed preservation technology, and FCF, each by 80%, 73%, and 95%, respectively. Farmers successfully produced FCF with good quality, as indicated by the acidic pH of 4.31. The palatability of FCF was also excellent for livestock. The average daily gain in sheep with FCF supplementation was 0.156 grams/head/day, while the farmers' feed supplementation was 0.113 grams/head/day. The community service activities in the Karya Manunggal livestock group conclude the improvement of farmers' knowledge and skills in terms of livestock nutritional needs, balanced feed formulation, and the utilization of fermentation technology in feed production. The success of these activities is also evident in the increased effectiveness of feed and cost efficiency following the implementation of FCF.
Artifacts and the Worship of Immortals: An Image Analysis of the Maoling Bamboo-Joint Boshan Furnace in the Han Dynasty
Authors: Yushu Liu
Published: May 2024

The Boshan furnace of the Han Dynasty is famous for its intricate carving, which possesses both decorative features and symbolic functions. The gilt silver and bamboo-joint bronze fumigation stove, with its continuous Boshan design, towering bamboo joints, and vivid carvings, reflects the two major characteristics of “beauty” and “utility” of the Ming Dynasty artifacts. This article mainly focuses on the transition from three-dimensional to two-dimensional imagery, the transformation of symbolic meanings into spatial analogues, and the comparative analysis of foreign and domestic shapes. The intention is to explore the morphological characteristics of Ming Dynasty artifacts through image research.
TESTING OF WHEAT GENOTYPES FOR SALT TOLERANCE AND LEAF RUST DISEASE CAUSED BY PUCCINIA
Authors: SAIFULDEEN SALIM  , FIRAS ALDULAIMY  , UTOOR ALDEEN
Published: May 2024

Parameters that show a significant genotypic variation and are associated with salt tolerance may be used as rapid and economic screening criteria in breeding programs. The objective of this study was to test growth and yield components for evaluating the salt tolerance of wheat genotypes. Five genotypes of winter wheat (Triticum aestivum L.) were used in this study, that differ from their salt tolerance, which were grown in 28 dS/m saline soil, and irrigated by well water with a salinity 7.5 dS/m. The results showed that salt concentration in the soil was reduced with plant growth stages from 28 dS/m before sowing to 8, 7.5, and 7.6 dS/m for N1, N2, and N3 genotypes, respectively. Whereas approached 16 and 17 dS/m for Tumos2 and Mexipak, cultivars, respectively, at the maturity stage. Concerning germination percentage under saline conditions, wheat genotypes N1, N2, and N3 showed the highest percentages of 89, 90, and 90%, respectively, which was significantly different than wheat cultivars Tumos2 and Mexipak 79 and 83%, respectively. Statistical analysis of the data revealed that genotype N2 required a maximum days for germination 14 days, whereas cultivarTumos2 required less days for germination 12 days. For spikes formation duration growth the genotype N3 was the late 119 days, whereas for physiological maturity N1 genotype was the latest 153 days. The number of spikes per 6 m2, grains spike-1, and grain weight were reduced significantly in sensitive cultivars Tumos2 and Mexipak. Higher grain yield with N2 genotype 2739.43 g with no significant differences with the genotypes N1 and N2, and with significant differences with the rest sensitive cultivars Tumos2 and Mexipak 346.61 and 242.98 g, respectively. Therefore, we conclude that the measurements of growth and yield components may be effective criteria for screening wheat genotypes for salt tolerance. Moreover, N1, N2, and N3 genotypes were identified as the most salt-tolerant genotypes in this study, they can be utilized through appropriate selection and breeding programs for further improvement in salt tolerance of Iraqi wheat genotypes.
CORRELATION AND PATH COEFFICIENT ANALYSIS RELATIONSHIPS IN SAFFLOWER (CARTHAMUS TINCTORIUS L.)
Authors: MALI BB  , WADIKAR PB  , KHANDEBHARAD PR
Published: May 2024

An experiment was conducted on 40 genotypes of safflower (Carthamus tinctorius L.) at the Experimental Farm of College of Agriculture, Latur, to examine genetic diversity and connections among characteristics. In Rabi 2020–2021, the experimental design was a complete randomized block design with two replications. The presence of considerable genetic diversity in the experimental materials was confirmed by analysis of variance results for 10 quantitative characters, which showed significant differences for all traits. The phenotypic and genotypic correlation among the traits and their path analysis were calculated. Plant height, number of branches per plant, number of effective capitulum per plant, number of seed per capitulum, and test weight were found to have a strong positive significant relationship with seed yield. This character had a strong and positive relationship toward seed yield. As a result, these characteristics could be considered important for improving safflower seed yield. The character number of branches per plant, plant height, number of effective capsules per plant, number of seed per capitulum, and test weight showed higher direct positive effects and indirect effects through other components traits. Number of seeds per capitulum had the greatest direct positive effect on seed yield per plant, followed by number of branches per plant and number of capsules per plant. As a result, these characteristics must be considered because they are directly relevant to seed yield. Characters like as days to maturity and oil content showed negative direct effects.
MOLECULAR DOCKING OF SPEARMINT PHYTOCOMPOUNDS AGAINST CYP21A2: IMPLICATIONS FOR PCOS THERAPY
Authors: MALAKHED SNEHA
Published: May 2024

Objectives: In this study, phytocompounds of spearmint that is known to have anti-androgenic activity are docked against a protein CYP21A2. This protein is also known as progesterone complex, one of the member cytochrome P450 enzymes; mutations in the genes encoding these proteins are causative factors of polycystic ovarian syndrome (PCOS).
Methods: The study was based on computations using different phytochemicals of spearmint docking to a target protein CYP21A2 which causes hormonal imbalance leading to PCOS and hirsutism. Molecular docking was conducted using PyRx-virtual screening tool and Biovia discovery studio 2.0 to determine binding affinities of different phytochemicals to target protein.
Results: The docking result revealed that bicyclogermacrene, cubebol, (-)-beta-bourbonene, alpha-bourbonene, and spathulenol showed highest binding affinities between –8.1 and –8.5 kcal/mol. Further, absorption, distribution, metabolism, excretion, and toxicity properties of these compounds are explored mainly to understand the possibility of developing potential drugs for PCOS.
Conclusion: These bioactive compounds can be considered as potential agents that can be used with polyherbal plant extract to reduce the androgen levels in women suffering from PCOS.
METHODOLOGY OF FEEDBACK SYSTEM IN EVALUATING THE FORMATIVE ASSESSMENT IN UNDERGRADUATE MEDICAL EDUCATION 2ND-YEAR PHARMACOLOGY: CONCEPTS, IMPLEMENTATIONS, AND HURDLES
Authors: GHULAM MOHAMMAD LOAN  , DEEPAK PRASHAR  , SANJAY KUMAR  , VIVEK KUMAR  , ERWIN M FALLER
Published: May 2024

The aim and objective of the study was to determine the teaching methods and their pros and cons that predominate in students in understanding and scoring in formative and summative assessments. Pharmacology is a course that needs extra care in this direction as this field is ever-changing. It is very difficult for a student to remember the classification of drugs, names, pharmacokinetics, pharmacodynamics, indications, contraindications, side effects, and adverse drug reactions. The present study focuses on the mental level and the economical aspects of the persons involved in the establishment of the medical college.
IN SILICO INVESTIGATION OF ECHINACEA PURPUREA PHYTO LIGANDS TARGETING HUMAN PAPILLOMAVIRUS TYPE 18’S L1 PROTEIN: IMPLICATIONS FOR CERVICAL CANCER MANAGEMENT
Authors: VINAYA VINOD SHINDE  , SAKSHI CHAUDHARY  , PARMINDER KAUR  , SWATI BANKARIYA
Published: May 2024

Objectives: Human papillomavirus (HPV) is a highly oncogenic virus responsible for the majority of intraepithelial lesions and cervical cancer. Among various HPV types, 16 and 18 contribute to approximately 70% of cervical cancer cases globally, making them the most prevalent high-risk oncogenic variants associated with this disease. Numerous vaccines (Gardasil 9, Gardasil, and Cervarix) have been approved by FDA to combat HPV infections; however, their widespread implementation faces challenges due to their limited cost-effectiveness.
Methods: Echinacea purpurea’s components have already been studied for in silico analysis against HPV Type 16’s L1 protein. In the present analysis, we aimed to explore the potential interaction between E. purpurea phytoligands (curcumin, echinacoside, and chicoric acid) and the major capsid protein L1 of HPV type 18 (2R5I) through molecular docking analysis.
Results: Molecular docking analysis revealed that the echinacoside, one of the components of E. purpurea, has the best binding affinity (−7.9 kcaL/moL) against the L1 protein of the HPV type 18.
Conclusion: The molecular docking analysis indicates that E. purpurea could act as an inhibitor against HPV infection. Further research and in vivo studies are necessary to confirm its efficacy as a cost-effective alternative to present HPV vaccines.
IMPROVING SPEAKING ABILITY IN DISCUSSION SESSIONS BY MANIPULATING THE INSTRUCTIONAL PODCAST CONTENT
Authors: Suseno Edy
Published: May 2024

Most of the EFL learners faced problems delivering ideas to other people, especially in discussion sessions. They need guidance to fix their flaws. Instructional podcasts can be a valuable resource for enhancing speaking abilities, especially in conducting debate. By manipulating the content of the podcasts, educators can create engaging and interactive speaking activities that promote language production and fluency. Whether it is through guided discussion, interactive tasks, or role-playing activities, instructional podcasts provide students with the opportunity to practice their speaking skills in a meaningful and enjoyable way. By incorporating these strategies into language learning curricula, educators can empower students to become confident and proficient speakers. Through the exposure of some perspectives and the adaptation of a qualitative method for using podcast materials to enhance the students’ success in discussion, it can be concluded that the students’ abilities in delivering ideas are developed in discussion sessions. This kind of finding is beneficial for teachers teaching-related subjects. It also inspires other researchers to observe related topics.
Alternative Algorithms for Time Series Water Wave Modeling
Authors: Hutahaean Syawaluddin
Published: May 2024

This research builds upon Hutahaean (2024a), focusing on time series water wave modeling, with substantial portions of this article derived from that prior study. Modifications were made to the calculation algorithm; specifically, vertical water particle velocity is now computed using the continuity equation, and water surface elevation is determined through kinematic free surface boundary conditions. While this revised algorithm enables the model to simulate wave breaking, it results in an excessively high breaker height and struggles to accurately simulate wave conditions post-breaking, particularly at large wave heights. To address these challenges, the kinetic energy conservation equation was integrated into the model. This addition facilitated the creation of a water surface elevation equation through the superposition of kinematic free surface boundary conditions and the kinetic energy conservation equation. This integration yields an equation that maintains a balance between changes in potential energy and changes in kinetic energy, enhancing the model’s capability to simulate both the shoaling-breaking process and subsequent wave conditions in shallow waters more effectively.
Alcances teológicos de la filología
Authors: Cobo-Reyes Lendínez Francisco Arsenio
Published: May 2024

A series of texts written by poets and critics is analyzed, from Matthew Arnold to Antonio Colinas, who have seen in poetry the possibility of finding a means of spiritual comfort or even a transcendent sense. The purpose is understanding how a discourse linking poetic words and the experience of transcendence has developed over time to open up the bases for a dialog between philology and theology. The text focuses, more than on theories and strictly theological terms, on showing, by means of the authors' literary reflections, those aspects of their discourse pointing out the existence of a trascendental phenomenon in poetry. In this way, the approach to a literary phenomenon so heterogeneous and determined for creating the poetical discourse of some of the most remarkable poets of the 20th and 21st centuries could be developed on the basis of greater theological and literary assurance.
Libros litúrgicos y paralitúrgicos en el Real Seminario de Minería de la Nueva España (1792-1825)
Authors: Becerra Ramírez Isaac
Published: May 2024

La Iglesia católica fue la institución más influyente del Imperio español, puesto que la religión permeó todas las instituciones modelando el carácter y vida de todos sus habitantes con la finalidad de formar buenos súbditos del rey a través de la educación y el culto. El objetivo principal del estudio es explicar la presencia y el uso de los libros litúrgicos y paralitúrgicos dentro del Real Seminario de Minería de la Nueva España como parte de la formación cívica y moral de los futuros peritos de minas, a través de documentación resguardada en el Palacio de Minería. La metodología es meramente histórica bibliográfica y recurro a fuentes primarias y aspectos teóricos de la liturgia para interpretar los datos apropiadamente. Como resultado se demostró que, a pesar de tratarse de una institución científica de corte ilustrado, la religión también penetró en el Real Seminario Metálico a través de dicho repertorio bibliográfico, constituido por libros presentes en todas las instituciones novohispanas y los cuales es imprescindible conocer, ya que pueden encontrarse en nuestras bibliotecas con fondos históricos.
Characterization and Performance Evaluation of Anaerobic Night Soil Biodegrading Inoculum
Authors: Kashyap Brijendra Kumar , Mathew Jose
Published: May 2024

The efficiency of anaerobic night soil (human excreta) biodegradation depends on the characteristics of the inoculum used. This anaerobic microbial inoculum (AMI) contains a microbial consortium, including rate-limiting methanogens whose growth depends on various physicochemical and biological parameters necessitating the inoculum characterisation essential for optimum night soil (NS) biodegradation. The inoculum contained 24.567 g/L (±0.07) total solid, 5.022 (±0.57) g/L total dissolved solid, 18.148 (±0.0.058) g/L volatile solid (VS), and 7.0±0.2 pH. The Gas chromatography analysis confirmed the presence of a small amount of volatile fatty acid (VFA), (≤ 4 mM except propionate) showing rapid conversion of VFA to methane, and 55% methane. Further, the presence of methanosaetaceae group of methanogens was detected through Taqman probe-based real-time PCR. The inoculum performance was evaluated for NS biodegradation in semicontinuous mode of feeding in four 2 L anaerobic biodigesters (2D HRT, 4D HRT, 5D HRT, and 10D HRT) with varying hydraulic retention time (HRT) (2, 5, 8, and 10 days, respectively) at mesophilic temperature (35°C). After 5 HRT, VS reduction for 2D HRT and 5D HRT was <40% while for 8D HRT and 10D HRT was >45-50% and >45-60%, respectively. The methane content was <20% in biogas for 2 and 5 days HRT while for 8 and 10 days >45-50% and 50-65% methane, respectively. The % VS reduction and methane content showed the overfeeding of NS in biodigesters 2D HRT and 5D HRT while 8D HRT showed towards optimum and 10D HRT optimum with improved VS reduction and methane content.
Fake Profile Detection in Instagram
Authors: Chaurasiya Adarsh , Verma Amrit , Shamitha Kota , Kumar Dr. Gaurav
Published: May 2024

Abstract: In today's society, online communities have become an integral part of daily life, with individuals actively engaging in social media interactions regardless of their location or schedule. However, the prevalence of pseudo personas has contributed to sophisticated persistent attacks and other malicious activities, raising concerns about the privacy of personal data among online community members. This research seeks to identify and address the pressing issue of fraudulent identity projection on social media platforms, particularly focusing on Instagram. By employing automated techniques such as predictive modeling and image identification combined with text analysis, the study aims to enhance the detection of fake profiles. The research utilizes the chi-square method for feature selection and applies learner-centered algorithms like Random Forest (RF) and logistic regression for categorization. The evaluation of outcomes will be based on metrics including relevance, specificity, recall, f1- value efficiency, and accuracy. The exponential growth and influence of social media globally have underscored the urgency of mitigating the proliferation of fraudulent identities, which pose challenges ranging from propaganda to racial profiling. The findings of this research are expected to contribute to the development of effective strategies for identifying and addressing fake profiles, thus safeguarding the integrity and security of online communities
A Collaborative Code Platform with Advanced AI Features and Real-Time Collaboration Tools
Authors: Gaikwad Aarti
Published: May 2024

Abstract: Good collaboration and code management are crucial in today's software development environment. Our research has launched a new collaborative process that combines AI resources, including AI and global research, to improve products and enhance and facilitate collaboration. The platform features real-time collaboration tools such as dynamic text with multilanguage support, dialog functionality, and notepad functionality. With OAuth authentication, users can seamlessly perform CRUD operations on files and directories, share code repositories, and participate in live coding sessions. The platform supports compilation and execution of a code file and follows good design principles such as caching, microservices architecture, and containerization to ensure scalability and performance. The platform focuses on user experience by providing simple user interface design and easy interface navigation. Users can create workspaces, share them collaboratively, and seamlessly import repositories from Git. The platform's intelligent data manager helps manage files and directories, while the collaborative platform allows developers to collaborate on code libraries efficiently. The platform is modern web-based, using React on the frontend and Node.js on the backend; Supported with syntax highlighting and smart initialization along with Socket.io for runtime with SQL and NoSQL databases. Provides comprehensive language support. All progress is saved, providing users with peace of mind. While the basic design is for desktops, future iterations are expected to support mobile devices.