bluuebunny/crossref_metadata_2025 huggingface dataset:
IMPLEMENTASI APLIKASI ANDROID MENGGUNAKAN APP INVENTOR
Authors: Haryanto Budi , Kurniawan Arif
Published: November 2022

ABSTRACTThe increasingly widespread use of smart phones, especially among students, has led to changes in information dissemination, from which information was simply posted in the announcement area on campus into information that can be accessed on cellphones.The development of android applications which dominate the majority of the smartphone market also makes the rapid growth of android-based applications, and the shift in the use of mobile web to mobile apps for the same type of application also underlies the purpose of this writing.There are many students who want to learn in making Android applications, but because they are hit by the need for expensive hardware, many of them discourage their desire to create Android applications, besides that because of the limitations of students who study and work, they do not allow it to automatically deep study the programming language needed.When trying out installations and trying to learn programming languages, many of them fall back in months, weeks and even days when they realize the difficulties of complex programming languages.Designing using an application design program that is easy and does not require high computer resources underlies the use of the app2inventor application to attract students to learn to make android applications.Keywords: Applications, Android, Information, App Inventor 2ABSTRAKPenggunaan ponsel cerdas yang semakin meluas terutama dikalangan mahasiswa, membuat penyebaran informasi juga mengalami perubahan yang tadinya informasi cukup ditempelkan di area pengumuman di kampus menjadi informasi yang dapat diakses di hp.Perkembangan aplikasi android yang mengusai sebagian besar pasar smartphone juga membuat pesatnya pertumbuhan aplikasi berbasis android, serta bergesernya penggunaan mobile web ke mobile app untuk jenis aplikasi yang sama juga mendasari tujuan dari penulisan ini.Mahasiswa banyak yang ingin belajar dalam pembuatan aplikasi android , tetapi dikarenakan terbentur oleh kebutuhan akan hardware yang mahal, membuat mereka banyak yang mengurungkan keingan untuk membuat aplikasi android, disamping itu karena keterbatasan yang di miliki oleh mahasiswa yang kuliah dan bekerja, mereka tidak memungkinkan untuk secara mendalam mepelajari bahasa pemrograman yang dibutuhkan.Saat mencoba instalasi dan mencoba belajar bahasa pemrograman banyak dari mereka yang mundur hanya dalam hitungan bulan, minggu bahkan hari saat menyadari kesulitan atas bahasa pemrograman yang rumit. Perancangan dengan menggunakan program perancangan aplikasi yang mudah dan tidak membutuhkan sumber daya komputer yang tinggi mendasari penggunaan aplikasi app2inventor untuk menarik mahasiswa belajar membuat aplikasi android.Kata kunci : Aplikasi, Android, Informasi, App Inventor 2
PEMANFAATAN E-COMMERCE DALAM MENINGKATKAN PENJUALAN DENGAN PENDEKATAN SISTEM BERORIENTASI OBJEK PADA D’SHOP
Authors: Aman Mustar
Published: November 2022

Perkembangan UMKM dari tahun ke tahun dipengaruhi dengan pemanfaatan Teknologi Informasi dan Sistem Informasi. e-commerce merupakan salah satu teknologi yang mendukung perkembangan UMKM dan perdagangan saat ini. D’SHOP merupakan perusahaan yang bergerak dibidang Butik yang menjual berbagai macam baju dan celana  dari mulai harga terendah sampai dengan harga tertinggi.Berdasarkan hasil analisa yang dilakukan pada D’SHOP Tangerang, maka peneliti dapat menyimpulkan bahwa Masalah yang terjadi pada Sistem penjualan pada D’SHOP adalah penjualan belum berbasis web atau e-commerce dan sistem pengelolaan data belum terkomputerisasi karena proses pengolahan data selama ini masih konvensional serta media promosi masih menggunakan brosur, spanduk dan kartu nama. Tujuan penelitian untuk mengetahui sistem penjualan dengan menggunakan analisis konseptual dan untuk mengetahui faktor pendukung dan faktor penghambat apa saja pada D’SHOP.Metode penelitian yang digunakan adalah kualitatif deskriptif. Tehnik pengumpulan data dilakukan dengan cara observasi, wawancara dan studi pustaka. Hasil penelitian ini diketahui managemen dapat dilihat pada beberapa proses yaitu membuat perincian harga produk, mengegola data pesanan, karyawan melakukan packing produk sampai melakukan pengiriman produk ke consumenKata Kunci : E-commerce, Perancangan, Penjualan, Objek Oriented
ANALISA & PERANCANGAN SISTEM INFORMASI JURNAL MAHASISWA BERBASIS WEB PADA STIE BISMA LEPISI
Authors: Hernanda Randyka Putra , . Nurasiah
Published: November 2022

Penelitian dalam skripsi ini dilatar belakangi oleh kegiatan-kegiatan yang berkaitan dengan administrasi maupun manajemen, namun masih sebatas untuk mengetik data mahasiswa baru dan alumni, untuk melakukan arsip manajemen jurnal mahasiswa belum menggunakan program khusus untuk membuat laporan yang berhubungan dengan pengolahan data dan informasi jurnal mahasiswa sehingga mengakibatkan keterlambatan akses informasi bagi mahasiswa, maka diperlukan sistem baru dengan menggunakan program khusus untuk mengolah data yang meliputi data informasi jurnal mahasiswa, dan data laporan sistem informasi jurnal mahasiswa, dengan adanya sistem baru akan mempermudah informasi yang cepat dan akan membantu maupun pimpinan dalam menerima laporan data sistem informasi jurnal mahasiswa pada STIE Bisma Lepisi, sehingga dapat menyajikan informasi kepada pengguna lainnya. Tujuan Penelitian ini adalah mengetahui sistem yang berjalan dalam persiapan jurnal mahasiswa di STIE Bisma Lepisi. Untuk merancang sistem  dokumentasi   jurnal   pada   STIE  Bisma  Lepisi Metode penelitian yang digunakan adalah metode pengumpulan data yaitu studi lapangan, wawancara, studi pustaka dan studi literatur sejenis dan Hasil penelitian ini adalah sistem informasi berbasis web yang dapat menambah efisiensi waktuKata Kunci : Analisa, Sistem, Perancangan, Jurnal, Lepisi, Website, mahasiswa
„Kreuzzeitung“ und „russische Grenze“ – Das historische und geographische Detail bei Theodor Fontane und Eduard von Keyserling
Authors: Hoge Boris
Published: November 2022

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Rebranding Britain: Cool Britannia, the Millennium Dome and the 2012 Olympics
Authors: Werther Charlotte
Published: November 2022

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Linguistische Untersuchungen zur strukturellen Gliederung, zur Verwendung von Personaldeixis und evaluativer Sprache in Rezensionen aus der Zeitschrift für deutsches Altertum und deutsche Literatur
Authors: Szurawitzki Michael
Published: November 2022

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Salgın Sonrası Yeni Gerçeklikle Yüzleşmek: Dijital Tüketicilerin Değişen Tepki ve Uyum Süreçleri
Authors: Arısoy Gedik Cansu , Pirol Melisa
Published: November 2022

Covid-19 salgını sebebiyle gündelik hayatın her alanında köklü değişiklikler yaşanmıştır; bireyler, çevrim dışı dünyanın ötesinde, her şeye ve herkese erişimi mümkün kılan dijital ağlardan daha fazla faydalanmaktadır. En büyük değişimlerden biri günlük hayatın en önemli unsurlarından olan tüketim davranışlarında gerçekleşmiştir. Bu bağlamda makalede yöntem olarak Covid-19 sonucunda Türkiye’de ve dünyada değişen satın alma davranışlarını gösteren araştırma verileri incelenmiş, Baudrillard’ın kavramsal çerçevesi ışığında literatür taraması yapılmıştır. İçinde bulunduğumuz yeni gerçeklik ve tüketici davranışları analiz edilirken Baudrillard’ın postmodern tüketim toplumu üstüne düşünceleri makalenin kuramsal perspektifini oluşturmuştur. Makalenin sorunsalı tüketicilerin salgının başında ve içinde bulunduğumuz günlerde tüketim alışkanlarının temel ihtiyaçlar ekseninden kaymasını kapsamaktadır. Bu bağlamda, çalışmanın araştırma sorusu şu şekilde belirlenmiştir: Postmodernizm ve dijitalleşmenin şekillendirdiği, her ihtiyacımızı dijital sosyal ağlar ile karşıladığımız günümüzde, bu durum postmodern tüketicinin satın alma davranışlarını değiştirmekte midir?

Bu çalışma, salgın sonrası dönemin yeni senaryosuna hazırlanmak, dünya yeniden normalleştiğinde, tüketicilerin dijitalleşme eğilimlerinin arttığı bir zaman diliminde, halkla ilişkiler ve reklamcılık uygulamalarında ortaya çıkacak tüketim trendlerini şimdiden görebilmek açısından önem taşımaktadır. 2022 itibari ile salgının üçüncü yılına girileceği düşünüldüğünde salgın sonrası dönemi kapsayan akademik, bilimsel çalışmaların yapılması, toplumların bu yeni gerçeğe adapte olması açısından hayati niteliktedir. Bu çalışmanın sonucunda, salgın sürecinde Türkiye’de ve küresel ölçekte belirli kategorilerdeki ürünlerin satış oranının azaldığı ve yaşanan kaygının tüketicide ürün stoklama ihtiyacı yarattığı görülmüştür. İkincil veri taramalarına göre sürecin devamında özellikle Türkiye’deki tüketicilerin satın alma davranışının yeni koşullara göre kalıcı biçimde değiştiği ve dijitalleşen tüketicilerin artık daha temkinli bir satın alma eğilimi gösterdiği dikkat çekmektedir. Bu süreçte tasarruf eden tüketicinin salgın sonrasında bastırılmış taleplerini satın alma davranışına dönüştüreceği öngörülmektedir.
Is the performance of the companies operating in the participation index in the Turkish economy affected by the macroeconomic perspective?
Authors: AVCI Pınar , SUMERLİ SARIGÜL Sevgi
Published: November 2022

This study aims to examine whether the participation index performance in the Turkish economy is going well in terms of macroeconomic factors over the period of January 2018March 2021. In this study, the cointegration between the variables is checked with the ARDL bound test and the Johansen cointegration method. The long-term coefficients are estimated through the ARDL model. Finally, the causal linkage among the participation index performance and traditional stock market index, short-term interest rate, money supply, and the inflation rate is tested with the Toda-Yamamoto causality method. The main empirical findings are shown as in the following: 1) there is cointegration between the Participation index performance and traditional stock market index, short-term interest rate, money supply, and inflation rate under the structural break, 2) the traditional stock market index and money supply improve the Participation index performance in Turkish economy while short-term interest rates hamper it, and 3) there is a two-way causality between the participation index performance and the traditional stock market index and inflation rate, and a one-way causality relationship running from money supply and interest rates to Participation index performance. These evidences provide important suggestions to investors in terms of portfolio diversification and to policymakers in the light of risk allocation and market policies.
Ernst Mayr’s Critique of Thomas Kuhn
Authors: Levit Georgy S. , Hossfeld Uwe ,   Institute of Philosophy, Russian Academy of Sciences
Published: November 2022

In the early 1960s, American philosopher of science Thomas Kuhn contributed to a “crisis of rationality” with his hypothesis that science develops by means of paradigm shifts. He challenged the positivist concept of cumulative and continuous scientific progress. According to Kuhn, the relation between two succeeding scientific traditions ‘separated by a scientific revolution’ is characterized by conceptual incommensurability that constrains the interpretation of science as a cumulative, steadily progressing enterprise. Thomas Kuhn’s philosophy was heavily criticized by German-American biologist Ernst Mayr as unapplicable to the history of biology. Mayr, one of the most outstanding evolutionary biologists of the 20th century and a “co-architect” of the so-called Modern Synthesis (contemporary Darwinism), published extensively on the history and philosophy of biology as he thought that theoretical biology cannot progress without proper philosophy of science. Being convinced of the progressive development of Darwinism, Mayr pointed out that Kuhn’s concept of scientific revolutions does not reflect conceptual changes in evolutionary biology. Here we summarize Mayr’s critiques of Kuhn and, based on our own research, take Mayr’s side in the controversy between two great thinkers.
How Parrhesia in Doing Philosophy with Children Develops Their Touchstones of Reality
Authors: Tillmanns Maria daVenza ,   National Philosophical Counseling Association
Published: November 2022

Parrhesia first appeared in Greek literature in the fifth century BC. Essentially, parrhesia refers to being granted the liberty to speak freely and openly without being deemed insubordinate to someone of greater authority and could otherwise lead to punishment or death. Parrhesia allows one to speak truth to power, essentially benefiting the one in power who lacks insight into the truth of a situation. In his book, Filosoferen met kinderen op de basisschool: een complexe activiteit, Berrie Heesen describes how doing philosophy with children is a form of parrhesia in that it encourages children to speak freely and openly. Parrhesia changes the adult/child relationship. Taken seriously by adults as full-fledged human beings creates a space for children to take themselves seriously while also being held responsible for what they think and feel. By giving reasons for their thoughts and feelings, and listening to those of their peers, children not only become critical listeners of others but also of themselves. They learn that what they think and feel matters – that they matter in the eyes of others and themselves, raising their self-esteem as well. In the process, children also develop their own touchstones of reality. Moreover, (self-) scrutiny is essential to feeling whole and grounded in who we are, giving us a sense of purpose and direction.
Fallacies in the Age of Social Media
Authors: Chaudhary Paridhi ,   National Philosophical Counseling Association
Published: November 2022

Social media is known to be one of the finest achievements of the 21st century. However, it is no surprise that there are two sides to every coin. While there are a lot of advantages of social media in our day-to-day life it is difficult to ignore its negative consequences. As the interactions between people have increased so have the standards and expectations of people and undoubtedly, so has the mental distress that people constantly face. Multiple researches conducted on the negative impacts of social media indicate towards the downside of social media, especially it's negative footprint on people's identities, social life, mental health and emotional well-being. Although there are various modalities that have been used to identify and solve the problems that people experience with social media, there are other modalities of counseling that have the potential to be effective and helpful but have not been explored in this regard. One such modality is Logic-Based Therapy. Logic-Based Therapy and Consultation is a philosophy-based practice that aims to help identify the different emotional and behavioral ways in which people upset themselves by their own faulty thinking. LBT identifies a number of fallacies or incorrect reasonings that people use very frequently in their lives and also suggests ways in which individuals can learn to cope with these fallacies. A lot of the fallacies identified by LBT can be seen in practice through social media. This paper aims at providing an insight into the reality of social media and online presence while highlighting the most common fallacies that people commit in emotional and behavioral reasoning as identified by LBT. The paper will also explore how and why people often commit these fallacies and suggest some antidotes to combat these fallacies.
LBT, Socratic Intellectualism, and Self-Knowledge
Authors: Gould Carol ,   National Philosophical Counseling Association
Published: November 2022

This paper offers a genealogy of the ancient predecessors of Logic-Based Therapy (LBT). While LBT has an apparent affinity with Stoicism, I argue that LBT has a tripartite foundation in Socratic Rational Inquiry, Platonic philosophical psychology, and Aristotelean ethics. Secondly, I argue that LBT could help a client attain self-knowledge and “moral proprioception.” Given that LBT involves an examination of one’s belief system(s) and a recognition of the subconscious faulty premises, it may implement a new, more adaptive understanding. By targeting self-defeating habits of interpreting the world, LBT can give clients a new self-understanding that enables them to interact with others and avoid unfortunate life choices and ways of interacting with significant others. I offer a hypothetical case from fiction pointing to the way LBT could transform the character’s life. LBT may enrich other therapeutic modalities, such as psychoanalysis or psychiatry, but it achieves different goals.
Black chronicle as a segment of the media agenda in daily newspapers in Serbia
Authors: Jevtović Ana , Bajić Predrag , Vojinović Maja
Published: November 2022

The paper problematizes substantial presence of black chronicle in print media reporting. Through a quantitative and qualitative analysis of the content of ten daily newspapers in Serbia, we researched genre characteristics and editorial policies used in presenting the content from the black chronicle segment. It can be seen that daily newspapers on a large-scale deal with the topic of violence and death, but also that the reporting quality does not correspond to the quantity of the published texts. Looking at the content, it can be concluded that serious daily press invests certain efforts in the maintenance of professional standards of the journalist profession, unlike tabloids that dominate the media space. During the analyzed time interval, there was almost not a single day when tabloids, on the pages reserved for the content from the black chronicle segment, did not reveal some details related to the lives of victims, possible perpetrators of criminal acts, as well as other actors, along with the observed violations of the rules of journalist ethics. Therefore, it is necessary to work on emancipation in two directions, towards greater responsibility of editorial staff, editors and journalists, and towards stronger media literacy of the public itself.
School as an educational context for the development of students' social competence
Authors: Zukorlić Mirsada , Nikolić Ivko
Published: November 2022

The paper discusses the possibilities of developing the social competence of students at school using the method of theoretical analysis. The school is expected to adapt its way of working with students to new needs, in order to develop certain segments from a number of individual and social abilities as a capacity for social success - social competence. The school, with its educational mission, within which the role of teachers is crucial, encourages social competences through: acquiring and expanding students' social knowledge and understanding of social reality; drawing students' attention to other people's feelings and interests; encouraging alternative interpretations of other people's behaviour; providing students with assistance in active participation in discussions; assisting students in discovering common features; supporting communication between students (fostering verbal and nonverbal communication); encouraging the constructive cooperation among students; strengthening empathy and strengthening altruism).
Changes in the value orientations of adolescents in the period 1972-2018
Authors: Radovanović Ivana , Spasić Danijela , Radovanović Dobrivoje
Published: November 2022

The current acceptance of value orientations by adolescents, changes in acceptance over time, and the connection with changes in social relations are undoubtedly of special interest to researchers, as well as certain segments of society. In this article, the results of the acceptance of the same value orientations at seven points in time, published in the works of different authors starting from 1972 as the first year in which data were available, were compared with the results of their acceptance at the eighth point, i.e., in 2018. The 2018 results were obtained by the author of this article, on a random sample of 832 secondary school students in Belgrade, with the same value orientations as in the previous seven papers: utilitarianism, hedonism, altruism, and activism. The number and type of value orientations are limited by the need to have the same ones throughout the time interval so that comparison is possible. The aim of the paper was: a) to determine the degree of desirability of these value orientations at the time of the research, and b) to determine the desirability changes and possible connection with social changes in the period from 1972 to 2018 (period of 46 years) by comparing the desirability of these value orientations in the same period. The data in previous surveys, before 2018, allowed comparison only in the mean values and calculation of the significance of the differences in them. The results obtained in that way showed the relative stability over time of the hedonic value orientation, a significant increase in the utilitarian value orientation and a significant decrease in the activist and altruistic value orientations. A logical analysis of these changes established their correspondence to the nature and the direction of changes in social relations in that period.
EMPIRICAL STUDY OF COGNITIVE AND SOCIAL MOTIVES OF TEACHING PRIMARY SCHOOL CHILDREN
Authors:   Murmansk Arctic State University, Panchenko T.V. , Shikhovtsova A.B.
Published: November 2022

An empirical study of cognitive and social motives of teaching primary school children is presented. The dynamics and interrelation of cognitive interests and upbringing of moral qualities, as well as the peculiarities of social motives of teaching in primary school students are described. It is established that the motives directly related to learning are not a priority in primary school age, but social motives embedded in educational activities dominate. During the educational process in primary school, there is no significant increase in the levels of formation of children’s cognitive interests, unlike moral qualities, the level of which is constantly improving.
ADAPTATION OF THE SYSTEM OF FORMATION OF CITIZENSHIP OF ADOLESCENTS IN THE PROCESS OF VOLUNTEER WORK TO THE IMPLEMENTATION OF NEW STRATEGIC OBJECTIVES EDUCATION AND UPBRINGING
Authors:   Center of continuing teachers’ professional upgrade “ARIPK”, Rakhmatulina B.R. , Verzhbitskaya E.G. Verzhbitskaya ,   Adyghe State University
Published: November 2022

The article considers the possibility of testing the adaptation of the model of the system of formation of citizenship of adolescents in the process of volunteer work. Quantitative indicators of the effectiveness of adaptation of the model of the system of formation of citizenship of adolescents in the process of volunteer work are presented to assess the qualities inherent in a citizen and assess the readiness of adolescents for volunteer work. The levels, means and forms of formation of citizenship of adolescents in the process of volunteer work have been developed, contributing to the formation of a stable civic position. The results of two modules of the conducted experiment on the formation of citizenship of adolescents in the process of volunteer work and the possibility of adapting the model of the system of formation of citizenship of adolescents in the process of volunteer work are presented. The results obtained by comparing the two modules of the experiment prove the stability of the formed civic position and the ability to adapt. Assessments of the qualities inherent in a citizen are represented by stable indicators, regardless of the experimental conditions. The conditions that can influence the stable civic position of students are determined. The data obtained as a result of the study and quantitative analysis allowed us to make a qualitative characteristic of the levels of citizenship formation of adolescents who participated in volunteer work.
Adaptive mixed-constraint Gerchberg-Saxton algorithm for phase-only holographic display
Authors: Gao Qian-Cheng , He Ze-Hao , Liu Ke-Xuan , Han Chao , Cao Liang-Cai ,   Key Laboratory of Advanced Perception and Intelligent Control of High-end Equipment, Ministry of Education, Anhui Polytechnic University, Wuhu 241000, China,   State Key Laboratory of Precision Measurement Technology and Instrument, Tsinghua University, Beijing 100084, China
Published: November 2022

At present, spatial light modulators are incapable of modulating both the amplitude and phase of the wavefront simultaneously. Therefore, when a spatial light modulator is used for holographic display, it is necessary to encode the complex amplitude of the object wave into amplitude-only or phase-only computer-generated-hologram. The phase-only holographic display has attracted much attention of researchers due to its characteristics of high diffraction efficiency and no conjugate image. However, current optimization algorithms for generating phase-only hologram have the problems of iterative divergence, slow convergence speed, and poor reconstruction quality, which is difficult to satisfy the requirements for high-quality holographic display. In this work, we propose an accurate adaptive mixed constraint Gerchberg-Saxton algorithm by constraining the frequency bandwidth in the hologram plane and adaptively constraining the amplitude of the reconstructed image in the image plane based on the angular spectrum propagation theory. Firstly, we use the angular spectrum propagation model without paraxial approximation to simulate the forward and backward propagation of the light wave for ensuring the accuracy of the wavefront propagation. Secondly, dividing the image plane into signal area and noise area according to the spatial distribution of target image, and different adaptive feedback strategies are set up for the two regions based on the optimized effect of the phase-only hologram. The adaptive feedback strategy is established, which can accelerate the convergence speed of the proposed algorithm and enhance the hologram of freedom of the optimization. Finally, the frequency bandwidth constraint strategy is introduced in the hologram plane to optimize the edge pixels and compensate for the frequency information loss of the phase-only computer-generated hologram, which improves the reconstruction quality of the hologram. After 100 iterations, the average correlation coefficient of the holographic reconstructed image of the proposed algorithm is about 0.9857, and the average peak signal-to-noise ratio is about 31.02 dB. The correlation coefficient and the peak signal-to-noise ratio of the reconstructed images of the proposed algorithm are better than those of the Gerchberg-Saxton algorithm with only frequency bandwidth constraint strategy, and the proposed algorithm has clearer texture and better display effect. The results of numerical simulations and optical experiments show the feasibility and effectiveness of the proposed method. The proposed adaptive mixed constraint Gerchberg-Saxton algorithm is a promising technology for high-quality holographic display.
Application of low flow rate micro gas cell nozzle in laser wakefield acceleration
Authors: Zhang Xiao-Hui , Wu Yu-Chi , Zhu Bin , Wang Shao-Yi , Yan Yong-Hong , Tan Fang , Yu Ming-Hai , Yang Yue , Li Gang , Zhang Jie , Wen Jia-Xing , Zhou Wei-Min , Su Jing-Qin , Gu Yu-Qiu ,   Science and Technology on Plasma Physics Laboratory, Research Center of Laser Fusion, China Academy of Engineering Physics, Mianyang 621900, China
Published: November 2022

After forty-year tremendous advances, laser wakefield acceleration (LWFA), in which an ultra-intense femtosecond laser interacts with a gas target to produce energetic electrons, is becoming more and more mature. Acceleration with a high repetition rate will be an important topic in the near future. When operating at a high repetition rate, the influence of the gas load on the vacuum system cannot be neglected. Among the widely used gas targets, gas cells have a lower flow rate than supersonic gas nozzles. However, most of gas cells are several centimeters long, unsuitable for a moderate-size laser facility. In this work, we design a kind of micro gas cell with a sub-centimeter length. The flow rate of the micro gas cell and the supersonic nozzle are compared by hydromechanics simulations. Comparing with the supersonic nozzle, the flow rate of the micro gas cell is reduced by 97%. Moreover, the gas cell sustains a longer flattop region. The reduced flow rate is attributed to two reasons. The first reason is that the area of the nozzle exit decreases significantly. In the case of the supersonic nozzle, the laser interacts with the gas jet outside the nozzle exit. Therefore, the exit size is determined by the interaction length. In the case of the micro gas cell, the laser interacts with the gas inside the gas cell. The exit only needs to be larger than the laser focal, which is much smaller than the interaction length. The second reason is that the velocity of the gas jet decreases. When using a supersonic nozzle, the velocity at the nozzle exit must be high enough to generate a flattop density distribution, which is required by LWFA. As a comparison, in the micro gas cell, the gas is confined by the cell wall. As a consequence, the gas velocity has little influence on the density distribution inside the cell. By changing the inner radius of the cell, 1–4 mm-long flattop regions can be generated while keeping a low flow rate. Experiments using the micro gas cell are conducted on a 45 TW femtosecond laser facility at the Laser Fusion Research Center. The stable electron beams with maximum energy of 250 MeV are generated. This study will contribute to the investigation of stable and high-frequency laser wakefield acceleration.
Explicit formulas for sums related to Dirichlet L-functions
Authors:   Department of Mathematics, University Kasdi Merbah, Ouargla, Mittou Brahim ,   EDPNL & HM Laboratory, ENS of Kouba, Algiers, Algeria
Published: November 2022

Let $p\geq3$ be a prime number and let $m, n$ and $l$ be integers with $\gcd(l,p)=1$. Let $\chi$ be a Dirichlet character modulo $p$ and $L(s,\chi)$ be the Dirichlet L-function corresponding to $\chi$. Explicit formulas for: $$\dfrac{2}{p-1} \sum \limits\sb{\underset{\chi(-1)=+1}{\chi\hspace{-0.2cm} \mod p}} \chi(l) L(m,\chi)L(n,\overline{\chi}) \text{ and }\dfrac{2}{p-1} \sum \limits\sb{\underset{\chi(-1)=-1}{\chi\hspace{-0.2cm} \mod p}} \chi(l) L(m,\chi)L(n,\overline{\chi})$$ are given in this paper by using the properties of character sums and Bernoulli polynomials.
Molecular basis of the PIP2-dependent regulation of CaV2.2 channel and its modulation by CaV β subunits
Authors: Park Cheon-Gyu , Yu Wookyung , Suh Byung-Chang
Published: November 2022

High-voltage-activated Ca2+ (CaV) channels that adjust Ca2+ influx upon membrane depolarization are differentially regulated by phosphatidylinositol 4,5-bisphosphate (PIP2) in an auxiliary CaV β subunit-dependent manner. However, the molecular mechanism by which the β subunits control the PIP2 sensitivity of CaV channels remains unclear. By engineering various α1B and β constructs in tsA-201 cells, we reported that at least two PIP2-binding sites, including the polybasic residues at the C-terminal end of I–II loop and the binding pocket in S4II domain, exist in the CaV2.2 channels. Moreover, they were distinctly engaged in the regulation of channel gating depending on the coupled CaV β2 subunits. The membrane-anchored β subunit abolished the PIP2 interaction of the phospholipid-binding site in the I–II loop, leading to lower PIP2 sensitivity of CaV2.2 channels. By contrast, PIP2 interacted with the basic residues in the S4II domain of CaV2.2 channels regardless of β2 isotype. Our data demonstrated that the anchoring properties of CaV β2 subunits to the plasma membrane determine the biophysical states of CaV2.2 channels by regulating PIP2 coupling to the nonspecific phospholipid-binding site in the I–II loop.
The CIC-ERF co-deletion underlies fusion-independent activation of ETS family member, ETV1, to drive prostate cancer progression
Authors: Gupta Nehal , Song Hanbing , Wu Wei , Ponce Rovingaile K , Lin Yone K , Kim Ji Won , Small Eric J , Feng Felix Y , Huang Franklin W , Okimoto Ross A
Published: November 2022

Human prostate cancer can result from chromosomal rearrangements that lead to aberrant ETS gene expression. The mechanisms that lead to fusion-independent ETS factor upregulation and prostate oncogenesis remain relatively unknown. Here, we show that two neighboring transcription factors, Capicua (CIC) and ETS2 repressor factor (ERF), which are co-deleted in human prostate tumors can drive prostate oncogenesis. Concurrent CIC and ERF loss commonly occur through focal genomic deletions at chromosome 19q13.2. Mechanistically, CIC and ERF co-bind the proximal regulatory element and mutually repress the ETS transcription factor, ETV1. Targeting ETV1 in CIC and ERF-deficient prostate cancer limits tumor growth. Thus, we have uncovered a fusion-independent mode of ETS transcriptional activation defined by concurrent loss of CIC and ERF.
High density and successful breeding of Turtle doves Streptopelia turtur in Moroccan olive groves
Authors: Squalli Wafae , Wink Michael , Mansouri Ismail , Fadil Fatima , Dakki Mohamed
Published: November 2022

Background

The turtle dove is a migratory species that has suffered a rapid decline principally across its Northern ranges, despite pronounced conservation measures. Consequently, it has been categorized as ‘Near Threatened’ in Europe. Degradation of breeding habitats and a decrease in food resources are listed as principal causes of this decline. Despite its importance, the productivity of the North African population is widely unknown. Here we present the first estimation of the density of the breeding population and the superior reproductively of Streptopelia turtur arenicola in Morocco and entire North Africa.

Methods

This study was carried out for two seasons 2018–2019 in the Saïss plain, central Morocco. Based on previous data, doves were monitored weekly, from early March to late August, in aquatic ecosystems (two dams and one river) and farmlands (cereals and orchards). The breeding population was censused using the “point-count” method, following a walked transect of 5 km in orchards, 7 km in cereal fields, and 3 km along the river. Equally, nests were searched in natural habitats counting riparian trees, forests, and ornamental trees, and in orchards based on the Common Birds Census (CBC) methodology, in which the singing doves, mating pairs, nesting, and/or feeding behavior were the most monitored signs to discover nests. In orchards, nests were searched line-by-line based on the rows of fruit trees. For each recorded nest, we note the breeding chronology, clutch size and incubation period, success and failure factors, dimensions, and vertical placement on trees. To evaluate the predictors of doves’ occurrence, we noted at each site the presence of cereals, water, human disturbance, presence of nesting trees, and predators.

Results and Discussion

In total, 3,580 turtle doves (22.37 birds/ha), including 240 breeding pairs, were documented. Nesting occurred mainly in olive groves, cereals were used for forage, and aquatic ecosystems for water sources. The nesting period lasted from late April to July (last fledglings). All nests were located on olive trees at a height of 225.30 ± 48.87 cm. The clutch size was 1.98 ± 0.13 (laid eggs/built nests), the incubation period lasted 14.16 ± 1.32 days, and the rearing period lasted 16.54 ± 1.76 days. The breeding success among the 240 monitored nests accounted for 73.84% during the nesting phase and 87.42% during the incubation phase; 71.5%% of nestlings have fledged, which is the highest success rate for turtle doves in Europe and Northwest Africa. Clutches were aborted mostly due to predation from snakes (7.5% of nests, 16.12% of eggs, and 5.63% of chicks), nest desertion (9.16% of nests and 5.37% of eggs), and marginally by the destruction of nests through farming activities. These findings are important for conservation plans, to restore turtle doves’ habitats in Europe, where the species is widely declining.
Evaluation of Antioxidant Effects of Antiepileptic Drugs in Adult Epileptic Patients: An Open Label, Non Randomised Interventional Study
Authors: Swathi B , Aruna D
Published: November 2022

Introduction: Oxidative stress is one of the factors implicated in the pathogenesis of epilepsy. Various antiepileptic drugs can control seizures by several mechanisms that may involve reduction of oxidative stress. Only a few studies have evaluated the antioxidant effects of Antiepileptic Drugs (AEDs). Aim: To evaluate the antioxidant activity of the AEDs (Phenytoin, Levetiracetam, Oxcarbazepine) in adult epileptic patients. Materials and Methods: The present open label, non randomised interventional study was conducted at the tertiary care hospital, Hyderabad, Telangana, India, from September 2016 to November 2017. Total of 45 subjects were divided into three groups, phenytoin group, levetiracetam group and oxcarbazepine group with 15 patients in each group. Blood samples were collected prior to initiation of treatment and after three months of treatment for measurement of antioxidative parameters such as Malondialdehyde (MDA), Nitric Oxide (NO) and reduced Glutathione (GSH) levels. Paired t-test was used for within group analysis. Results: The mean age was 28.92±9.62 years, mean weight was 55.87±10.73 kg and mean Body Mass Index (BMI) was 21.99±3.82 kg/m2 . No statistically significant difference was seen in all oxidative parameters in phenytoin treated group. In levetiracetam group, significant decrease in MDA levels and increase in GSH levels was observed after three months of treatment. In oxcarbazepine group, statistically significant decrease was found in MDA and NO levels and increase in GSH levels was observed. Conclusion: It was concluded that phenytoin has no role in reducing oxidative stress in epileptic patients, whereas levetiracetam decreases lipid peroxidation and oxcarbazepine has beneficial role in reducing oxidative stress in adult epileptic patients.
Diagnostic Accuracy of FNAC and Ultrasonography in Salivary Gland Lesions in Comparison with Histopathology
Authors: Khan Shaheen , Nair Nandakumar Gopinathan
Published: November 2022

Introduction: Modern era demands for early and accurate diagnosis. Fine Needle Aspiration Cytology (FNAC) and Ultrasonography (USG) are two such diagnostic modalities which have gained importance in recent years due to their rapid, repeatable and precision properties. Aim: To study the accuracy of FNAC and USG in diagnosing salivary gland lesions in comparison with histopathology and to study the expression of p63 and Cytokeratin 7 (CK7) Immunohistochemical (IHC) markers in malignant salivary gland tumours. Materials and Methods: A cross-sectional study was conducted on 106 cases who presented with salivary gland lesions possessing USG reports and underwent FNAC and surgical specimens received in Cytopathology and Histopathology Department, Government Medical College Thiruvananthapuram, Kerala, India during one year period (February 2017-January 2018). In each case FNAC was performed and slides were stained with Papanicolaou and Giemsa, surgical specimens were grossed, histopathological features studied under microscope and tumours classified according to World Health Organisation (WHO) Classification of Salivary gland Tumours 2017. Diagnosis on USG and FNAC were compared with histopathological diagnosis. Sensitivity, specificity, Positive Predictive Value (PPV), Negative Predictive Value (NPV), diagnostic accuracy, concordance and discordance was calculated by Statistical Package for the Social Sciences (SPSS) software 24.0 version. p63 and CK7 IHC markers were done only in malignant salivary gland tumours. Results: In the present study majority of lesions i.e. 82 cases (77.4%) were seen predominantly in parotid gland and pleomorphic adenoma was the most commonest lesion and neoplasm overall with 50 cases (47.2%). Most common malignant neoplasm was mucoepidermoid carcinoma (four cases, 3.8%). USG and FNAC had high diagnostic accuracy of 89.6% and 97.2% in comparison to histopathology in diagnosing salivary gland lesions. Conclusion: High sensitivity and specificity of USG and FNAC makes them most acclaimed preoperative diagnostic modality for salivary gland lesions, but histopathology remains gold standard. Subtyping of malignant and cystic lesions were difficult in USG and cytology
Clinical and Biochemical Profile of Children on Follow-up with Autoimmune Thyroiditis
Authors: Venugopal Veena , Anirudhan Deepa
Published: November 2022

Introduction: Hashimotos Thyroiditis (HT) is the most common autoimmune thyroid disease and the most common cause of acquired hypothyroidism in children. Understanding the clinical profile in children with Autoimmune Thyroiditis (AIT) helps in follow-up and appropriate management of the condition. Aim: To assess the clinical, biochemical profile and the course of disease in children with AIT. Materials and Methods: This was a hospital-based longitudinal study done at a Paediatric endocrinology clinic, from January 2018 to June 2019, at southern India on all children with autoimmune thyroiditis on follow-up for at least three years, aged up to18 years, attending the clinic. Clinical examination for thyroid swelling, anthropometry of the child, Tanner staging for pubertal status, Thyroid Stimulating Hormone (TSH), and free Thyroxine (T4) were done at enrollment and also at followup after one year. Results: A total of 33 children were enrolled into the study. Of this, girls constituted 85%, with a female to male ratio of 5.6:1. Mean age at diagnosis was 9.76±1.69 years; 25 (75.7%) were hypothyroid and 8 (24.2%) were euthyroid at presentation; 21 (64%) had a positive family history of thyroid illness. The most common presentation was goitre (88%), 32 (96.9%) of them had positive thyroid antibodies either Antithyroid Peroxidase (TPO) or anti thyroglobulin (Tg) antibody. Of the 32 children with positive antibodies, 26 (78.7%) had raised anti TPO and 17 (51%) had positive anti Tg; 12 (36.3%) were positive for both anti TPO and anti Tg; 29 patients(78.7%) required treatment with thyroxine. All were noted to be pubertal but with no significant growth impairment. On follow-up after 1 year, the percentage of hypothyroid patients increased from 75.7% to 97%, and 1(3%) became hyperthyroid. None of them had other autoimmune disorders during follow-up. Conclusion: Children with AIT were mostly females and the majority had goitre. The prevalence of goitre was 88% and the majority were hypothyroid at presentation. A majority of children with autoimmune thyroiditis had a positive family history of thyroid disease. On follow-up after at 1 year, all the euthyroid patients had become hypothyroid. The thyroid status of children with autoimmune thyroiditis can change over time and needs regular clinical and biochemical follow-up.
Profile of Cluster Frontline Demonstration Beneficiaries in Madhya Pradesh and Chhattisgarh State
Authors: Shrivastava Sanjana , Naberia Seema , Singh S. R. K.
Published: November 2022

Cluster Frontline Demonstration (CFLD) is a unique approach by the Indian Council of Agricultural Research on Oilseed crops to provide a direct interface between scientists and farmers where farmers are guided by the KVK scientists during demonstrations in implementation of improved technologies like seed treatment, IPM, INM, land preparation and so on, Demonstrated fields are regularly monitored by the scientists. The present study was carried out to know the profile of CFLD beneficiaries in selected districts of Madhya Pradesh and Chhattisgarh over a complete sample of 346 beneficiaries. The results revealed that majority of the CFLD beneficiaries were in middle age (61.57%), belongs to male category (86.13), educated up to middle school (26.98), had large family size (40.17%), medium social participation (50.00%), medium material possession (61.27%), medium annual income (67.92%), large size of land holding (46.54%), had more than 0.4 ha land under oilseed crop (48.26%) with good cropping pattern (44.52%), had medium level extension participation (74.27%), medium information seeking behaviour(64.16%), medium mass media exposure (84.11%), medium scientific orientation (53.18%), medium innovativeness (58.96%), medium risk preference (55.20%), medium knowledge about oilseeds (63.53%), had fair management efficiency (62.13%), attended more than one training programme (63.01%) under cluster frontline demonstration.
Chromium Induced Developments of Diseases and their Inhibitions by Cargos
Authors: Mandal Ardhendu Kumar
Published: November 2022

The exposure of hexavalent chromium (Cr-VI) mainly through the inhalation, skin contact or oral administration by the environmental chromium industrial processes causes the major toxicity-induced health hazardous mortality throughout the world. Though reduced chromium (Cr-III), as an essential micronutrient, is utilized to maintain the normal blood glucose, lipid and protein profiles through the metabolism in the body to activate the action of the hormones such as insulin, the high concentration exposures of Cr-VI and Cr-III cause oxidative stress-induced DNA oxidation and adducts, DNA strand breaks and mutations, DNA-protein cross-links, membrane-lipid peroxidation and reduced/altered antioxidant/immune response activities, leading to cellular damage-related various diseases and the development of malignant cancer.

Applications of different cargos may inhibit Cr-VI or its intermediates-induced cytotoxicity, immunotoxicity, or genotoxicity through chromium-chelating and scavenging free radical reactive species, restoring antioxidant and immune response activities or arresting disease-oriented signal transductions or other pathways at cellular and molecular levels. This review mainly demonstrates  the development  of various  diseases by chromium exposure and their inhibitions by cargos.
Effect of Precursor and Temperature Annealing on the Catalytic Activity of Intermetallic Ni3Sn2 Alloy
Authors: Rodiansono Rodiansono , Azzahra Atina Sabila , Husain Sadang , Ansyah Pathur Razi
Published: November 2022

The effect of nickel precursors and the temperature annealing to obtain intermetallic Ni3Sn2 alloy catalysts on its activity and selectivity in the selective hydrogenation of biomass-derived furfural (FFald) were investigated. Two types of nickel precursors (c.a., i) nickel metal (Ni°) derived from Raney®nickel and ii) nickel ion (Ni2+) derived from nickel chloride) were employed as the starting materials via hydrothermal at 423 K for 24 h followed by reduction with H2 at the elevated temperature of 573-873 K for 1.5 h. The physico-chemical properties of the intermetallic Ni3Sn2 were characterized by XRD, N2-, and H2-adsorption, ICP-AES, and NH3-TPD. The intermetallic Ni3Sn2 alloy catalysts, both bulk and supported, demonstrated high activity and selectivity towards hydrogenation of FFald. The activity and selectivity of g-Al2O3 and AA-supported Ni3Sn2 alloy catalysts in the hydrogenation of FFald to furfuryl alcohol (FFalc) were maintained even after annealing at up to 873 K, but that of bulk Ni3Sn2 drastically dropped. Ni-Sn alloy catalysts which were obtained from Raney®Ni precursor showed more stable than that of nickel salts during hydrogenation of furfural to furfuryl alcohol. Copyright © 2022 by Authors, Published by BCREC Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).