bluuebunny/crossref_metadata_2025 huggingface dataset:
NORMAS DE CRIANZA Y EL DESARROLLO SOCIOAFECTIVO DE LOS NIÑOS DE PREPARATORIA: ESCUELA DE EDUCACIÓN BÁSICA “DR. ALEJO LASCANO
Authors: Andrade Arroyo Glenda Patricia , Marcillo Rengifo Patricia Maribell , Palma Moreira Mary Vanessa , Solórzano Bravo Fanny Monserrate , Zambrano Vélez Lídice Isabel
Published: May 2024

Este estudio indaga sobre las normas de crianza y su impacto en el desarrollo socioafectivo de los niños de preparatoria en la Escuela de Educación Básica “Dr. Alejo Lascano”, en la parroquia rural El Anegado del cantón Jipijapa en el período comprendido del 2023-2024. La problemática se evidencia en las diversas prácticas de crianza de los padres de familia hacia los estudiantes, lo que genera disparidades en la forma en que los niños desarrollan sus habilidades sociales y afectivas. Es por ello, que el objetivo consistió en fomentar apropiadas normas de crianza, mediante talleres para promover el desarrollo socioafectivo en los niños y niñas de la escuela mencionada. Se empleó una investigación descriptiva, además del método cuantitativo a través de la técnica de las encuestas realizadas a los padres de familia y la ficha de observación a los niños, los resultados revelaron que el 18% está en desacuerdo con la responsabilidad de los familiares en inculcar normas de crianza, mientras que el 82% considera que estas normas promueven un clima de respeto y empatía en la escuela.
INTELIGENCIA ARTIFICIAL Y SU CONTRIBUCIÓN A LA INNOVACIÓN EN LAS EMPRESAS
Authors: Calle García Jonás Sneider , Sotaminga Andi Ailen Stefania , Garay Arias Gleise Nicole , Villavicencio Tuares Richard Roberto
Published: May 2024

Este estudio se centra en la contribución de la inteligencia artificial (IA) a la innovación en las empresas, es por ello que el objetivo principal es determinar cómo la IA impulsa la innovación y determinar los desafíos asociados con su implementación. Para ello se empleó una metodología que combinó la revisión de literatura, análisis de casos de estudio y datos de mercado para comprender el impacto de la IA en diferentes sectores empresariales. Los resultados revelaron que la IA ofrece beneficios significativos, como optimización de procesos, mejora en la toma de decisiones y personalización de experiencias para los clientes. Además, se examinó cómo empresas de diversos sectores están adoptando y beneficiándose de la IA, resaltando porcentajes específicos que respaldan estas tendencias. Por ejemplo, se destacaron datos como el 25% de las empresas que integrarán NLP en sus sistemas de atención al cliente para 2025, o el 80% de las empresas que informan mejoras en la eficiencia operativa después de implementar soluciones de ML en sus operaciones. Sin embargo, se identificaron desafíos, como la falta de talento especializado, preocupaciones sobre privacidad de datos y resistencia cultural.
A hybrid annual runoff prediction model using echo state network and gated recurrent unit based on sand cat swarm optimization with Markov chain error correction method
Authors: Wang Jun , Wang Wenchuan , Hu Xiao-xue , Gu Miao , Hong Yang-hao , Zang Hong-fei
Published: May 2024

This study proposes a hybrid model based on the combination of Sand Cat Swarm Optimization (SCSO), Echo State Network (ESN), Gated Recurrent Unit (GRU), Least Squares Method (LSM), and Markov Chain (MC) to improve the accuracy of annual runoff prediction. Firstly, conduct correlation analysis on multi-factor data related to runoff to determine the input of the model. Secondly, the SCSO algorithm is used to optimize the parameters of the ESN and GRU models, and the SCSO-ESN and SCSO-GRU models are established. Next, the prediction results of these two models are coupled using LSM to obtain the preliminary prediction results of the SCSO-ESN-GRU model. Finally, the initial prediction results are corrected for errors using MC to get the final prediction results. Choose Changshui Station and Lanxi Station for experiments, and evaluate the predictive performance of the model through five evaluation indicators. The results show that the combined prediction model corrected by the MC achieved the optimal prediction performance at both experimental stations. This study emphasizes that using a combination prediction model based on Markov chain correction can significantly improve the accuracy of annual runoff prediction, providing a reliable basis for predicting annual runoff in complex watersheds.
Effect of seed priming on growth and yield parameters of maize
Authors: Dawadi Ebha , Chaudhary Srijana , Karki Ambika , Dhungana Srijana
Published: May 2024

Maize is the principal food crop of people living in inner Terai region of Nepal. This region receives comparatively less rainfall that results in insufficient seedling emergence and inappropriate stand establishment. So seed priming is simple cost-effective and easily implementable technique that ensures better germination and crop establishment as well as enhancing production. The study was conducted from February 2021 to May 2021 in farmer’s field, Hadiya-9, Udaipur to examine how the growth and yield parameters were affected by seed priming. The experiment was laid out in single factor randomized complete block design with 3 replications and 7 treatments namely T1: control, T2: hydro priming for 6 h, T3: hydro priming for 12 h, T4: zinc sulphate priming (0.5 % for 12h), T5: zinc sulphate priming (1 % for 12 h) and T6= zinc sulphate priming (2 % for 12 h), T7= cow urine priming (2 times dilution). Results showed that there was a significant effect on the germination percentage, germination index, days to 100 % germination, leaf number, days to tasseling and silking, cob length, kernel per cob, cob girth, total plant population per hectare, 1000 grain weight, grain yield, biological yield and harvest index of corn. Hydro priming for 18 h (T3) and Cow urine priming 2.5 times dilution for 12 h (T7) were found to be most effective priming solution showing higher influence in germination percentage, germination index, days to 100 % germination, leaf number, days to tasseling and silking, plant height, cob length, kernel per cob, total plant population per hectare and harvest index. To sum up, the result indicate that the findings suggest that using hydro priming for 18 h and cow urine priming 2.5 times dilution for 12 h as seed priming agents can significantly improve the growth and yield parameters of corn. This study clarifies the potential of several compounds used during seed priming to improve corn development and production.
LIDERANÇA ESTRATÉGICA DE PESSOAS COMO PRÁTICA DE ENGAJAMENTO NA ÁREA DE TECNOLOGIA DA INFORMAÇÃO
Authors: Fernandes Roberto Fabiano , Barbosa da Costa Clayton , Dos Santos Faustino Röder Elisângela
Published: May 2024

This article is the result of a research whose theme addressed the strategic management of people and organizational leadership applied in the area of Information Technology (IT), and which discussed the practices identified to obtain greater engagement of employees in the IT area and alignment with the strategic objectives aiming at the best return for the organization. This return can occur financially or by raising the levels of collaboration, creativity and satisfaction of employees in the organizational environment. Strategic people management introduces concepts of organizational culture and leadership, direction and planning that are essential to promote a functional environment of cooperation and integration. The general objective of the research was to identify and present people management practices applied in the IT area of organizations that have led them to a change of attitude in relation to the management of work teams. The study was qualitative, descriptive and was developed in the form of field and bibliographical research based on books and scientific articles. The result achieved was the indication of best leadership and people management practices that promote engagement and the best performance of IT professionals to achieve organizational objectives, based on the intersection between the concepts taken from the theoretical content and the data obtained through search.
A LEI GERAL DE PROTEÇÃO DE DADOS PESSOAIS À LUZ DA CIÊNCIA DA INFORMAÇÃO
Authors: Melo Rinaldo Ribeiro de , Batista Getúlio Valdemir , Lima Paulo Ricardo Silva
Published: May 2024

The objective of the research was to present the bibliometric panorama of the scientific productions in the field of Information Science, indexed in the Reference Database of Articles from Periodicals in Information Science that deal with the General Personal Data Protection Law. This is an exploratory research with a quanti-qualitative approach that used the bibliometric method to analyze the data. The results point to a low number of productions (22) and researchers (55), in Information Science, engaged in discussions about the General Personal Data Protection Law, since only four authors published more than one paper on the subject. The themes discussed in the texts point to the concern of the authors with current and sensitive issues discussed both in the area of Information Science and in society. Finally, it is understood that, although discussions about the General Personal Data Protection Law are still incipient in the area of Information Science, justified by the short time that this law has been in force, it is possible to infer an increase in production and research interest based on the increase of papers published per year and by the discussions that have been occurring in society on issues related to the theme of this research.
INDICADORES PARA AVALIAÇÃO DA VISIBILIDADE DAS PATENTES EM UNIVERSIDADES FEDERAIS
Authors: Vasconcelos Jandira , Lima Francisco Valdivino Rocha , Santos João Antonio Belmino dos
Published: May 2024

Increasingly, universities are contributing to technological development due to the high production of patents. Researchers use indicators related to patent dynamics as a means of evaluating the innovative process in universities, but the instruments until then do not signal their disclosure. In view of the above, this article aims to develop and validate a model to evaluate the visibility of university patents, based on a set of indicators. For this purpose, the model was initially constituted by the preliminary definition of the indicators and their classification according to the scope, in the second stage it was given by the evaluation, through the Fuzzy Delphi method, in order to determine which indicators should remain. After validation, the final model was composed of 14 indicators, categorized into 3 dimensions. It is expected that with the proposed model, the application of the same can contribute to more dissemination of university patents in order to achieve more visibility, as well as expand technology transfers.
Proteomics Approach to Identify Serum Biomarkers Associated with
Gastric Cancer in South Indian Tamils
Authors: Chithra Madhesh Jeevitha , Narasiman Manojkumar , Nagarajan Vignesh , S Meenalosani , Varshikaa Sweta , Sivagnanam Ananthi , Jayaraman Megala
Published: May 2024

Background::

Identifying cancer-specific biomarkers is a crucial step in the disease
screening process at a very early stage of tumor development. In recent years, Quantitative proteomic
approaches have gained importance in identifying novel candidate markers in cancer.
Gastric cancer has always been known as a life-threatening medical condition with high mortality
rates.

Objectives::

The objective of our research is to adapt serum samples from Indian gastric cancer
patients to identify and understand the differentially regulated proteins in comparison with
healthy individuals.

Methods::

A total of 30 serum isolates from gastric cancer patients and healthy individuals were
obtained and subjected to 2-D Gel electrophoresis, and Tandem LC-MS analysis revealed 12
differentially expressed protein spots. The functional properties of identified proteins were further
analyzed using PANTHER and STRING databases.

Results::

The differentially expressed protein spots were identified as three candidate proteins:
Haptoglobin, Prohibitin, and Apolipoprotein. The protein interaction studies reveal that the haptoglobin
fragments were upregulated, and the remaining two prohibitin and Apolipoprotein
were down-regulated in gastric cancer patients.

Conclusion::

All the proteins identified as biomarkers were found to be involved in regulating
cell proliferation and stabilization of oxidative metabolism in the liver; therefore, differential
regulation plays a crucial role in gastric cancer progression.
Disposition Kinetics of Cathinone and its Metabolites after Oral Administration in Rats
Authors: Sabei Fahad Y. , Khardali Ibrahim , Al-Kasim Mohamed A. , Shaheen Emad Sayed , Oraiby Magbool , Alamir Ahmad , David Banji , Alshahrani Saeed , Jali Abdulmajeed M. , Attafi Mohammed , Albeishy Mohammed Y. , Attafi Ibraheem
Published: May 2024

Background:

Cathinone is a natural stimulant found in the Catha edulis plant. Its derivatives make
up the largest group of new psychoactive substances. In order to better understand its effects, it is imperative
to investigate its distribution, pharmacokinetics, and metabolic profile. However, the existing literature on
cathinone remains limited.

Objective:

This study aimed to investigate the disposition kinetics and metabolic profile of cathinone and its
metabolite cathine through a single oral dose of cathinone administration in rats.

Methods:

Cathinone and cathine concentrations were identified and quantified using ion trap liquid chromatography-
mass spectrometry (LC-IT/MS). The metabolic profile in the serum, brain, lung, liver, kidney, and heart
was analyzed at specific time points (0, 0.5, 2.5, 6, 12, 24, 48, and 72 hours) using the ultra-high performance
liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS) method.

Results:

The highest concentration of cathinone was found in the kidney (1438.6 μg/L, which gradually decreased
to 1.97 within 48 h and disappeared after 72 h. Cathinone levels in the lungs, liver, and heart were
859, 798.9, and 385.8 μg/L, respectively, within half an hour. However, within 2.5 hours, these levels decreased
to 608.1, 429.3, and 309.1 μg/L and became undetectable after 24 h. In the rat brain, cathinone levels
dropped quickly and were undetectable within six hours, decreasing from 712.7 μg/L after 30 min. In the brain
and serum, cathine reached its highest levels at 2.5 hours, while in other organs, it peaked at 0.5 hours, indicating
slower conversion of cathinone to cathine in the brain and serum.

Conclusion:

This study revealed a dynamic interplay between cathinone disposition kinetics and its impact on
organ-specific metabolic profiles in rats. These results have significant implications for drug development,
pharmacovigilance, and clinical practices involving cathinone. Investigating the correlation between the
changes in biomarkers found in the brain and the levels of cathinone and cathine is essential for informed decision-
making in medical practices and further research into the pharmacological properties of cathinone.
Stimuli-sensitive Chitosan-based Nanosystems-immobilized Nucleic Acids
for Gene Therapy in Breast Cancer and Hepatocellular Carcinoma
Authors: Naghib Seyed Morteza , Ahmadi Bahar , Mozafari M. R.
Published: May 2024

Chitosan-based nanoparticles have emerged as a promising tool in the realm of cancer
therapy, particularly for gene delivery. With cancer being a prevalent and devastating disease, finding
effective treatment options is of utmost importance. These nanoparticles provide a unique solution
by encapsulating specific genes and delivering them directly to cancer cells, offering immense
potential for targeted therapy. The biocompatibility and biodegradability of chitosan, a naturally
derived polymer, make it an ideal candidate for this purpose. The nanoparticles protect the genetic
material during transportation and enhance its cellular uptake, ensuring effective delivery to
the site of action. Furthermore, the unique properties of chitosan-based nanoparticles allow for the
controlled release of genes, maximizing their therapeutic effect while minimizing adverse effects.
By advancing the field of gene therapy through the use of chitosan-based nanoparticles, scientists
are making significant strides toward more humane and personalized treatments for cancer patients.
Nonsurgical Minimally Invasive Endodontic Treatment of Large Periapical Lesions: A Report of Three Cases
Authors: Van Le Hong , Trinh Vu Hai , Vu Thai Son , Nguyen Tuan Anh
Published: May 2024

Introduction

Periapical lesions develop as a result of microorganisms from necrotic pulp tissue or retained foreign bodies in the periapical tissue, leading to acute or chronic inflammation. It has been proven that the majority of inflammatory periapical lesions can be effectively treated using nonsurgical endodontic management. However, the selection between surgical and nonsurgical endodontic treatment for managing large periapical lesions remains a controversial issue. This report aims to reveal the effectiveness of nonsurgical, minimally invasive endodontic treatment for large periapical lesions in conjunction with lesion decompression and aspiration.

Case Presentation

This article presents three cases with large periapical lesions related to severe bone destruction with different causes that were managed with nonsurgical endodontic treatment, involving multiple visits for intracanal medication with calcium hydroxide. In all three cases, the long-term clinical assessments and CBCT scans consistently showed complete healing. The follow-up period ranged from 24 to 48 months.

Conclusion

The successful results demonstrated the efficacy of nonsurgical endodontic management, which is a minimally invasive approach when addressing large inflammatory periapical lesions with diverse causes.
Impulsivity: A Transdiagnostic Approach to Understanding Adolescent Substance Use
Authors: Lamichhane Bishal , Li Zishen , Sabharwal Ashutosh , Moukaddam Nidal
Published: May 2024

Background:

Impulsivity, characterized by the tendency to act on
impulse without consideration for consequences, has been implicated in health
disorders such as problematic substance use among adolescents. Understanding
impulsivity's nature, clinical manifestations, quantification, and management in a
clinical context could help address underlying disorders.

Methods:

We reviewed previous studies where different impulsivity dimensions
were identified and explored the manifestations of impulsivity across conditions
characterized by high impulsivity. Similarly, we pursued a literature search on
various factors influencing impulsivity, methods employed to quantify them, and
commonly used treatments for impulsivity control.

Results:

The multidimensional and transdiagnostic nature of impulsivity was
acknowledged across several studies. Various health disorders such as substance
use disorders, borderline personality disorder, and attention-deficit/hyperactivity
disorder implicated impulsivity, even among the adolescent groups. We identified
biological, psychological, and environmental factors influencing impulsivity. We
also present the commonly employed approaches to quantifying impulsivity and
new measurement approaches under active investigation that are relevant in
characterizing impulsivity in adolescents. Treatment options to manage
impulsivity were also reviewed and are presented in this work.

Conclusion:

This work offers a comprehensive understanding of impulsivity as
one of the underlying factors in adolescent substance use and related health
disorders, emphasizing factors affecting impulsivity, approaches for
measurement, and implications of high impulsivity on mental health and
behaviors.
critical discourse analysis study of stance taking and positioning in American and Russian political speeches
Authors: Al-Azzawi Qasim Obayes , Majeed Serin
Published: May 2024

The goal of the current study is to look into the various stance-taking techniques utilized in American and Russian political speeches. Examining these forms' lexical and grammatical forms, semantic and discoursal roles, and social relevance in establishing the speaker's place and ideology are all important. Thus, based on Fairclough's (1995) dialectical-relational approach of CDA, the current study analysis six political speeches. They study concludes that the prevalent application of certain markers, whether in terms of highly significant words or grammatical things, has symbolically conveyed the speakers level of confidence and knowledge. Their adoption of engagement formalizations demonstrated their propensity to consider other people's perspectives, but they do not value them as highly as their own beliefs and attitudes. They create a dialogue space for different viewpoints, but they take care to prevent them from receiving the same endorsement as their own. Engagement conveys a conviction in this way.
Physician and Practice Characteristics Influencing Telemedicine Uptake Among Frontline Clinicians in the Early COVID-19 Pandemic Response: National Survey Study
Authors: Hamline Michelle Y , Xing Guibo , Kravitz Richard L , Miller Marykate , Melnikow Joy
Published: May 2024

Background

 Telemedicine expanded rapidly during the COVID-19 pandemic, as key policy changes, financial support, and pandemic fears tipped the balance toward internet-based care. Despite this increased support and benefits to patients and clinicians, telemedicine uptake was variable across clinicians and practices. Little is known regarding physician and institutional characteristics underlying this variability.

Objective

 This study aimed to evaluate factors influencing telemedicine uptake among frontline physicians in the early pandemic response.

Methods

 We surveyed a national stratified sample of frontline clinicians drawn from the American Medical Association Physician Professional Data in June or July 2020. The survey inquired about the first month and most recent month (June 2020) of pandemic telemedicine use; sample data included clinician gender, specialty, census region, and years in practice. Local pandemic conditions were estimated from county-level data on COVID-19 rates at the time of survey response. Data were analyzed in a weighted logistic regression, controlling for county-specific pandemic data, and weighted to account for survey data stratification and nonresponse.

Results

 Over the first 3-4 months of the pandemic, the proportion of physicians reporting use of telemedicine in >30% of visits increased from 29.2% (70/239) to 35.7% (85/238). Relative to primary care, odds of substantial telemedicine use (>30%) both during the first month of the pandemic and in June 2020 were increased among infectious disease and critical care physicians and decreased among hospitalists and emergency medicine physicians. At least minimal prepandemic telemedicine use (odds ratio [OR] 11.41, 95% CI 1.34-97.04) and a high 2-week moving average of local COVID-19 cases (OR 10.16, 95% CI 2.07-49.97) were also associated with substantial telemedicine use in June 2020. There were no significant differences according to clinician gender, census region, or years in practice.

Conclusions

 Prepandemic telemedicine use, high local COVID-19 case counts, and clinician specialty were associated with higher levels of substantial telemedicine use during the early pandemic response. These results suggest that telemedicine uptake in the face of the pandemic may have been heavily influenced by the level of perceived threat and the resources available for implementation. Such understanding has important implications for reducing burnout and preparation for future public health emergencies.
Digital Interventions for Self-Management of Type 2 Diabetes Mellitus: Systematic Literature Review and Meta-Analysis
Authors: Kerr David , Ahn David , Waki Kayo , Wang Jing , Breznen Boris , Klonoff David C
Published: May 2024

Background

The proliferation of digital technology has the potential to transform diabetes management. One of the critical aspects of modern diabetes management remains the achievement of glycemic targets to avoid acute and long-term complications.

Objective

This study aims to describe the landscape of evidence pertaining to the relative effectiveness or efficacy and safety of various digital interventions for the self-management of type 2 diabetes mellitus (T2DM), with a primary focus on reducing glycated hemoglobin A1c (HbA1c) levels.

Methods

A systematic literature review (SLR) was conducted by searching Embase, MEDLINE, and CENTRAL on April 5, 2022. Study selection, data extraction, and quality assessment were performed by 2 independent reviewers. Eligibility criteria for the SLR included randomized controlled trials (RCTs) and comparative observational studies evaluating interventions containing both human (eg, coaching) and digital components (eg, glucose meter) in adult patients with T2DM. The primary meta-analysis was restricted to studies that reported laboratory-measured HbA1c. In secondary analyses, meta-regression was performed with the intensity of coaching in the digital intervention as a categorical covariate.

Results

In total, 28 studies were included in this analysis. Most studies (23/28, 82%) used the reduction of HbA1c levels as the primary end point, either directly or as a part of a multicomponent outcome. In total, 21 studies reported statistically significant results with this primary end point. When stratified into 3 intervention categories by the intensity of the intervention supporting the digital health technology (analyzing all 28 studies), the success rate appeared to be proportional to the coaching intensity (ie, higher-intensity studies reported higher success rates). When the analysis was restricted to RCTs using the comparative improvement of HbA1c levels, the effectiveness of the interventions was less clear. Only half (12/23, 52%) of the included RCTs reported statistically significant results. The meta-analyses were broadly aligned with the results of the SLR. The primary analysis estimated a greater reduction in HbA1c associated with digital interventions compared with usual care (–0.31%, 95% CI –0.45% to –0.16%; P<.001). Meta-regression estimated reductions of –0.45% (95% CI –0.81% to –0.09%; P=.02), –0.29% (95% CI –0.48% to –0.11%; P=.003), and –0.28% (95% CI –0.65% to 0.09%; P=.20) associated with high-, medium-, and low-intensity interventions, respectively.

Conclusions

These findings suggest that reducing HbA1c levels in individuals with T2DM with the help of digital interventions is feasible, effective, and acceptable. One common feature of effective digital health interventions was the availability of timely and responsive personalized coaching by a dedicated health care professional.
Mersivity: XRSC (eXtended Reality Spatial Computing) for Health, Well-Being, and Accessibility (Preprint)
Authors: Hosseingholizadeh Aydin , Isiksalan Mete , Mann Steve , Jiao Aoran , Kumar Nishant , Mok Gavin , Chen Emily , Cho Alex , Ho Daniel , Yoo Ted , Kazimierczak Mateusz , Lee Somin Mindy
Published: May 2024

UNSTRUCTURED

This paper provides an overview of Mersivity, also known as Vironmentalism or XRSC (eXtended Reality Spatial Computing) with applications in health, well-being, and accessibility. There is a growing interest in technologies that are ’mersive (immersive, submersive, or supermersive), i.e. technologies that encapsulate or enclose or surround us. Examples include “wearables”, immersive VR (Virtual Reality), and electric vehicles such as self-driving cars, vessels, and personal aircraft (ABC = Aircraft, Boats, Cars). It is widely agreed that there is a risk or danger of asymmetry of immersive technologies that can separate us, harmfully, from our surroundings. In order to support human health, well-being, and accessibility, it is essential that we can ’merse any of these technologies that ’merse us. If one can’t go for a hike in the forest or along the beach (and maybe go for a swim as well) with the technologies that claim to help us, then those technologies are actually harming us. Thus an important element of Mersivity is a connection to the physical world = the world of “atoms” = nature = the environment = sustainability = our surroundings. Mersivity therefore is at the nexus of the physical (nature/sustainability/environment), virtual, and social worlds. In this paper we provide a historical perspective on XR+SC, from the early spatial computers of the 1970s, the introduction of XR=eXtended Reality in 1991, and leading up to the latest trends such as the “Freehicle” = vehicle of freedom for those with disabilities. See Fig 1.
Analysis of load distribution after transpedicular stabilization of burst fractures in the thoracolumbar junction
Authors: Nekhlopochyn O.S. , Verbov V.V. , Cheshuk Ie.V. , Karpinsky M.Yu. , Yaresko O.V.
Published: May 2024

Background. In the structure of all traumatic spine injuries, the thoracolumbar junction is predominant, accounting for over 53 % of all vertebral fractures. One of the most clinically significant types of injuries in this area are burst fractures. The purpose was to study the stress-strain state of the thoracolumbar spine model with a burst fracture of the Th12 vertebra in various transpedicular fixation options under compression load. Materials and methods. The study developed and investigated a finite element model of the thoracolumbar spine with a burst fracture of the Th12 vertebra. The burst fracture was modeled by dividing the vertebral body of the Th12 into several planes, transforming it into separate fragments. The gaps between these fragments were filled with a material that simulated the interfragmentary regenerate. Variants of transpedicular stabilization using different types of screws, mono- or bicortical, and with or without cross-links, were examined. The model was analyzed under compression load. Results. The maximum level of stress among the bone structures directly involved in fixation was registered in the L2 vertebral body. It amounted to 19.9, 15.6, 19.4, and 15.1 MPa, respectively, for models with monocortical screws without cross-links, bicortical screws without cross-links, monocortical screws with cross-links, bicortical screws with cross-links. Simultaneously, the zone of screw entry into the arch of this vertebra shows values of 10.1, 15, 10.2, and 14.3 MPa for these models, respectively. Peak loads on the metal structure elements are observed on the rods, amounting to 212.5, 159.6, 203.7, 142.8 MPa, respectively, for the considered models. Conclusions. The results of the study showed that under the influence of compression load when modeling a burst fracture of the thoracolumbar junction, the use of long screws leads to a reduction in stress levels, both in the elements of the metal structure and in the bone elements of the model, while the use of cross-links has a negligible effect.
CHRONICLES OF HEALING: UNVEILING THE SECRETS OF ABRASION AND LACERATION DATING IN FORENSIC PATHOLOGY
Authors: CHOYAL MAHAVEER , BANSOD PRIYANKA , VYAS P. C. , KOODI GURUSHARAN
Published: May 2024

Objective: In the field of forensic pathology, understanding the timeline of injury occurrence is of paramount importance. This study, titled "Chronicles of Healing: Unveiling the Secrets of Abrasion and Laceration Dating in Forensic Pathology," conducted a postmortem investigation to assess wound dating by gross and histopathological examination of blunt injuries.
Methods: A total of 195 case samples from 119 cases were scrutinized to establish the timing of various gross changes and microscopic alterations that transpire following blunt trauma. The study encompassed abrasions, contusions, and lacerations occurring within a time frame ranging from 0 h to a maximum of 45 d.
Results: The findings revealed that the gross changes in abrasions closely correlated with the corresponding microscopic changes, while contusions exhibited a similar correlation, except for a variation in the appearance of bluish color. In lacerations, the correlation was primarily evident during the early stages of injury.
Conclusion: Importantly, the study emphasized the substantial impact of comorbid conditions on the healing process, highlighting the need for cautious evaluation in such cases. The study concludes that naked eye examination alone is insufficient for precise injury dating, underscoring the importance of histopathological examination to ensure accurate conclusions regarding injury age.
QUALITATIVE AND QUANTITATIVE ANALYSIS OF PHYTOCONSTITUENTS IN THE UNANI FORMULATION HABB-E-BUKHAR
Authors: FIRDOUSE SEEMA , AHMED SHOYEB , MUNAIM MOHAMMED ABDUL
Published: May 2024

Objective: Habb-e-Bukhar is a specific medication regimen in the traditional unani system for treating fever caused by conditions such as elephantiasis and intestinal diseases. It acts as both an Antipyretic and Diaphoretic to address acute fever.
Methods: The current research aims to analyze the qualitative and quantitative composition of Habb-e-Bukhar to assess the primary and secondary metabolites present in the sample extract. The study utilized a range of advanced analytical methods such as FTIR, AAS, HPLC, and GC-MS analysis. The sample was prepared through the maceration method, and an initial phytochemical screening revealed the presence of Alkaloids, Carbohydrates, Volatile oils, Flavonoids, Glycosides, Steroids, and triterpenoids.
Results: The Fourier-transform infrared spectroscopy reveals the identification of functional groups at specific wavenumbers: 3960.26 for Amide, 3687.85 for Alcohol, 2765.05 for Aliphatic, and 2099.54 for Alkynes; as well as, at wavelength of 1641.55 denoting the presence of Alkenes (C=C). Moreover, findings from the Atomic Absorption spectrometer suggest that the drug contains notable levels of certain heavy metals, such as chromium at 0.00642 ppm, lead at 10.00 ppm, and argon at three ppm detected with precision in their respective wavelengths.
Conclusion: The GC-MS technique was utilized to detect and characterize the phytochemicals found in the ethanolic extract. The findings indicated the existence of seven constituents.
SOCIOECONOMIC FACTORS AND HEALTHCARE ACCESS: THEIR ROLE IN THE MANAGEMENT AND OUTCOMES OF DIABETIC FOOT ULCERS
Authors: SINGH AJIT , AGRAWAL AMIT , ARORA AMAN
Published: May 2024

Objective: Diabetic foot ulcers (DFUs) are a significant complication of diabetes mellitus, affecting millions globally and presenting considerable challenges to healthcare systems. While clinical aspects of DFUs are well-documented, socioeconomic factors and healthcare access play crucial roles in their management and outcomes. This study investigates how socioeconomic status (SES), healthcare accessibility, and patient education influence DFU prevention, treatment, and prognosis.
Methods: A prospective, cross-sectional observational study was conducted over 13 mo at the Department of General Surgery, Command Hospital (Western Command), Chandimandir. Fifty patients with DFUs were enrolled based on specific inclusion and exclusion criteria. Data were collected on demographic details, lifestyle habits, comorbidities, and specifics of diabetes and DFU. Ulcer characteristics, wound cultures, and outcomes were analyzed using SPSS version 21.0.
Results: The study population had a mean age of 60.10 y, with a predominance of males (78%). Smoking and obesity emerged as significant risk factors, with smoking more prevalent among males and obesity more common in females. The distribution of ulcer locations and the microbial profile, dominated by Staphylococcus aureus, underline the complexity of DFU management. These findings highlight the influence of socioeconomic factors and healthcare access on DFU outcomes.
Conclusion: Effective DFU management requires a holistic approach that extends beyond clinical treatment to address socioeconomic factors and healthcare access. Tailored interventions that consider these broader determinants of health are essential for improving DFU outcomes and patient quality of life. Addressing healthcare disparities can significantly reduce the burden of DFUs, creating a more equitable and effective framework for diabetes care.
COMPARATIVE ANALYSIS OF PHYTOCHEMICALS IN ACACIA CATECHU BARK EXTRACTS FROM GUNA DISTRICT, MADHYA PRADESH
Authors: TIWARI ARCHANA , TIWARI AVINASH
Published: May 2024

Objective: Current study aims to discover novel sources of physiologically active natural chemicals with diverse applications. In this study, four types of specific phytochemical in different extracts of Acacia catechu bark samples were investigated, which were collected from. Additionally, bibliographic analysis was conducted using dimensions research database.
Methods: For this phytochemical screening, some common and standard test methods were done. Qualitative test for Phenols was done using Lead acetate test method; proteins were quantified by biuret and ninhydrin method, carbohydrates by Molish test, benedict’s test and Fehling’s test, and starch by using Iodine test method.
Results: Phytochemical screening showed the phenolic compounds (different colour intensity in different samples) and soluble carbohydrates (almost same colour intensity in all test samples) are present and both proteins and insoluble carbohydrate (starch) are completely absent in all test extracts.
Conclusion: The bibliographic analysis indicated the therapeutic values as well as the unavailability of published studies with these special parameters. This preliminary study provide base to find out the possible medicinal significance of Acacia catechu of Guna district and also serve as the base for further investigations.
CADASIL-A RARE PRESENTATION OF STROKE
Authors: DAMA AASHISH , JAIN PULKIT , SINGH JITENDRA , SALVE CHANDRA KANT , SHARMA ASHISH
Published: May 2024

Objective: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary syndrome caused by heterozygous mutations in the NOTCH3 gene that manifests in adulthood and is characterized by recurrent transient ischemic attacks and strokes, migraine-like headaches, psychiatric disturbance, and progressive dementia.
Methods: This is a case report.
Results: Current case presented with complain of dizziness and vomiting. The diagnosis was suspected mainly because of the typical brain magnetic resonance imaging (MRI). This shows the importance of brain MRI in the diagnosis of CADASIL.
Conclusion: Increased awareness of neurologists and neuroradiologists about the typical MRI features of CADASIL is of vital importance to reach the diagnosis in a timely manner.
Salient Features of Tertiary Education Subsidy on University Students’ Persistence
Authors: Bulilan Ramil S.
Published: May 2024

The study determined the extent of awareness of students on the critical features of the Tertiary Education Subsidy (TES) program towards their college persistence. It then sought data on their demographics, determined the extent of awareness of TES salient features and the level of persistence in their studies on the nine factors, and identified the difference between their profile and their persistence. It also determined the correlation between the level of awareness of TES salient features and persistence. The descriptive-correlational survey method and the stratified random sampling technique obtained 171 TES grantees as respondents. It revealed that they were so much aware of TES salient features and were persistent in their studies. There was no significant difference in sex and top priority items spent on their persistence in schooling; however, it resulted in a positive difference between their chosen course and marital status on their persistence level. The study also yielded a significant relationship between the extent of awareness and their persistence. It is indicative, therefore, that being cognizant of any government program for students’ welfare would lead them toward better decision-making.
The Poetics of the Thing in M. Duras’s L’Amante Anglaise: From Evidence to Minus-device
Authors: Fedunina Olga
Published: May 2024

The paper considers the structural and functional specifics of the portrayal of things in the novel “La menthe anglaise” by M. Duras. In the framework of the analysis it is stated that the traditional for criminal plot function of a thing as a clue is absorbed here by another, less obvious and related to the search for the “right question” about the true reason of the murder. The “getting rid” of things as traces of their presence in the everyday, purely material world takes place both at the narrative and plot scales. Having lost its external instantiation, having retained only its name in a few lists, the object is actually swallowed up by the word, by speech. The detected singularities give a fuller picture of the correlation of M. Duras’s novel with the traditions of criminal literature and the French “new novel”, namely with one of its basic principles, the detailed depiction of things (le chosisme) beyond semantic and symbolic connections, as identical to themselves.
Poetics of Things in Kalmyk Tales about Animals
Authors: Khaninova Rimma , Chumbaeva Anna
Published: May 2024

The article examines the poetics of things in Kalmyk fairy tales about animals. The research material included both published and unpublished texts of Kalmyk fairy tales about animals in the original and translated into Russian, as well as legends and traditions. Despite the fact that when studying Kalmyk fairy tales about animals related to the genre, plot, composition, system of characters, and linguistic means, researchers touched upon such material culture to one degree or another, the objective world of such fairy tales did not become the object and subject of a separate study. Results. In representative Kalmyk tales about animals, object realities related to different spheres of material culture were found: types of housing and its decoration, non-residential buildings, tools and materials, household utensils, weapons and hunting tools, musical instruments, vehicles, etc. One of them is used by people and animals, others - only by people. Some objective realities are created by animals. In the plot collisions of fairy tales, things are used for one purpose or another by people and animals or only by people, while the same thing can have different functions, for example, attack and defense. In the only case, the thing is endowed with the magical ability of the donor. Some things reveal only the objective background against which certain events occur. Subject realities have both a universal and local, ethnic character.
Algunas reflexiones sobre la condición
Authors: Cruz Martínez Mario
Published: May 2024

Número 100Enero - Abril 2001Nueva Serie Año XXXIVISSN 0041 8633 Mario CRUZ MARTÍNEZ * En este trabajo se analiza el concepto de condición y su evolución en diversos ordenamientos jurídicos. El punto de partida es el debate relativo a las modalidades del negocio jurídico, con una particular referencia al estudio del contrato. En una primera parte, el autor se refiere al tratamiento que la perspectiva romanística dio a la condición, aludiendo por ejemplo a los criterios de clasificación de distintos tipos de condición; al problema de la retroactividad o irretroactividad de sus efectos al cumplirse la condición, así como a algunos casos prácticos. En una segunda parte, el estudio se dedica a analizar algunos aspectos de la condición en el derecho moderno, para terminar con una reflexión acerca de la condición en los proyectos de códigos tipo., *Técnico académico del Instituto de Investigaciones Jurídicas de la UNAM. * Nota: Debido que la traducción es automática podrá ser inexacta o contener errores.
Definitividad del procedimiento administrativo fiscal
Authors: Rodríguez Lobato Raúl
Published: May 2024

Número 100Enero - Abril 2001Nueva Serie Año XXXIVISSN 0041 8633 ADMINISTRATIVO FISCAL Raúl RODRÍGUEZ LOBATO * En opinión del autor del presente artículo, la certeza y la seguridad jurídicas en relación con el procedimiento administrativo fiscal no tienen reconocimiento directo y expreso en el Código Fiscal de la Federación. Esta omisión es inadecuada, debido a que del procedimiento administrativo se derivan importantes derechos y obligaciones tanto para la autoridad fiscal como para el contribuyente, que debieran estar respaldados por un principio de seguridad jurídica perfectamente regulado en las leyes respectivas. Para sustentar esta opinión, el autor realiza un estudio de diversos aspectos del procedimiento administrativo: sus características, desarrollo, eficacia y principios generales, haciendo una revisión de la doctrina tanto nacional como extranjera, así como de criterios derivados de la jurisprudencia., *Profesor de la Facultad de Derecho de la UNAM. * Nota: Debido que la traducción es automática podrá ser inexacta o contener errores.
Iglesia y Estado. Notas sobre su diferenciación
Authors: Orrego Sánchez Cristóbal , Saldaña Javier
Published: May 2024

Número 102Septiembre - Diciembre 2001Nueva Serie Año XXXIVISSN 0041 8633 IGLESIA Y ESTADO. NOTAS SOBRE SU DIFERENCIACIÓN Cristóbal ORREGO SÁNCHEZ * Javier SALDAÑA SERRANO ** El Estado democrático exige como uno de sus presupuestos el principio de la igualdad jurídica de las religiones. Esto obliga a los especialistas en derecho eclesiástico a buscar nuevas fórmulas de explicación que justifiquen tanto su materia, como la actualización de sus principios, sin renunciar al núcleo que le dio origen, es decir, a la consideración de una plena autonomía e independencia entre la Iglesia y el Estado. En el presente ensayo, los autores asumen ese reto, bajo la idea de que el derecho eclesiástico debe adaptar sus presupuestos básicos a la cambiante rea-lidad social, sin perder de vista que la Iglesia y el Estado son dos ámbitos independientes entre sí, aunque unidos en un lugar común: la persona humana. , *Profesor de filosofía jurídica y política de la Universidad de los Andes (Chile). Actualmente trabaja en el Proyecto Fondecyt, número 1990734, titulado "Principios generales del derecho y regulación del fenómeno religioso". El coautor agradece la ayuda complementaria de Fundación Andes en la investigación de este tema, mediante una beca del Programa de Estadías de Investigación 1999, segunda etapa. **Profesor investigador del Instituto de Investigaciones Jurídicas de la UNAM y visitante académico en la Universidad de los Andes (Chile), invitado por Fondecyt (Proyecto número 7990062 de Incentivo a la Cooperación Internacional). * Nota: Debido que la traducción es automática podrá ser inexacta o contener errores.
Comercio y medio ambiente: aportaciones desde la perspectiva del acuerdo de libre comercio Chile-Canadá
Authors: Peña-Neira Sergio
Published: May 2024

Número 102Septiembre - Diciembre 2001Nueva Serie Año XXXIVISSN 0041 8633 COMERCIO Y MEDIO AMBIENTE: APORTACIONES DESDE LA PERSPECTIVA DEL ACUERDO DE LIBRE COMERCIO CHILE-CANADÁ Sergio PEÑA-NEIRA * En la primera parte, el autor establece un marco teórico y expone las diferentes posturas de distintos sectores frente a las relaciones entre comercio y medio ambiente. El autor parte de que dicha relación ha superado el terreno estrictamente económico, para convertirse en un fenómeno cuya problemática y soluciones deben ser abordados por el derecho. De esta manera, el autor analiza la reglamentación y las soluciones existentes en materia ambiental en el Tratado de Libre Comercio entre Chile y Canadá, y en el Acuerdo sobre Medio Ambiente entre estos dos países, entre las que destacan los procedimientos de consulta, imposición de sanciones y de solución de controversias. Por último, el autor expone la regulación canadiense en cuanto al comercio marítimo y el medio ambiente, tomando en consideración las dificultades que puede traer aparejado el hecho de que la legislación canadiense en esta materia es más avanzada que la chilena. * Profesor ayudante en la Universidad del Mar, Chile, e investigador del Centro de Ecología Teórica y Aplicada de la citada casa de estudios. El autor desea resaltar que ete trabajo ha contado con el generoso apoyo del gobierno de Canadá a través del programa Faculty Enrichement Program que le fue otorgado en 1998. Mediante dicha beca se pudo efectuar la investigación para dar curso al presente texto. Tal investigación fue efectuada en enero y febrero de 1999 en la Sección de Derecho Civil de la Facultad de Derecho de la Universidad de Ottawa, Canadá. * Nota: Debido que la traducción es automática podrá ser inexacta o contener errores.