bluuebunny/crossref_metadata_2025 huggingface dataset:
Development and validation of a novel stem cell subtype for bladder cancer based on stem genomic profiling
Authors: Tang Chaozhi , Ma Jiakang , Liu Xiuli , Liu Zhengchun
Published: May 2020

Background
Bladder cancer is the fifth most common type of cancer worldwide, with high recurrence and progression rates. Although considerable progress has been made in the treatment of bladder cancer through accurate typing of molecular characteristics, little is known about the various genetic and epigenetic changes that have evolved in stem and progenitor cells. Thus, we developed a novel stem cell typing method to fill this gap.
Methods
Based on six published genomic data sets, we used 26 stem cell gene sets to classify each data set. Unsupervised and supervised machine learning methods were used to perform the classification.
Results
We classified BLCA into three subtypes—high stem cell enrichment (SCE_H), medium stem cell enrichment (SCE_M), and low stem cell enrichment (SCE_L)—based on multiple cross-platform data sets. The stability and reliability of the classification were verified. The stemness index obtained from the one-class logistic regression machine learning method showed that the degree of tumor stem cell enrichment was not proportional to the stemness index. Compared with the other subtypes, SCE_H showed the highest degree of cancer stem cell concentration, lowest stemness index, and highest level of immune cell infiltration and was the most sensitive to predicted immune checkpoint inhibitor treatment. However, this group showed the worst prognosis. Comparison of gene set enrichment analysis results for pathway enrichment of various subtypes revealed that the SCE_H subtype activates some important pathways regulating cancer occurrence, development, and even poor prognosis, including epithelial mesenchymal transition, hypoxia, angiogenesis, KRAS signal up-regulation, the interleukin 6-mediated Jak-STAT signaling pathway, and inflammatory response. Two identified pairs of transcription factors, GRHL2 and GATA6 and IRF5 and GATA3, likely have opposite regulatory effects on SCE_H and SCE_L, respectively.
Conclusions
The identification of BLCA subtypes based on cancer stem cell gene sets revealed the complex mechanism of carcinogenesis causing BLCA and provides a new direction for the diagnosis and treatment of BLCA.
Network pharmacology of AYUSH recommended immune-boosting medicinal plants against COVID-19
Authors: Khanal Pukar , Duyu Taaza , Dey Yadu Nandan , Patil B M , Pasha Iasmail , Wanjari Manish
Published: May 2020

Background: The Ministry of AYUSH recommended the use of a decoction of the mixture of Ocimum tenuiflorum, Cinnamomum verum, Piper nigrum, Zingiber officinale, and Vitis vinifera as a preventive measure to boost immunity and to inhibit the severity of infection caused by a novel coronavirus (COVID-19). Objective: The present study aimed to identify the probable modulated pathways via AYUSH recommended formulation as an immune booster against COVID-19.Materials and methods: Reported phytoconstituents of all the plants were retrieved from the ChEBI database, and their targets were predicted using DIGEP-Pred. STRING database and Cytoscape were used to predict the protein-protein interaction and construct the network interaction respectively. Likewise, MolSoft and admetSAR2.0 were used to predict the druglikeness score and ADMET profile of phytoconstituents. Results: The study identified the modulation of HIF-1, p53, PI3K-Akt, MAPK, cAMP, Ras, Wnt, NF-kappa B, IL-17, TNF, and cGMP-PKG signaling pathways to boost the immune system. Further, multiple pathways were also identified which are involved in the regulation of pathogenesis of the multiple infections and non-infectious diseases due to the lower immune system.Conclusion: Results indicated that the recommended herbal formulation not only modulated the pathways related to boost the immune system but also modulated the multiple pathways that are contributing in the progression of multiple disease pathogenesis which would add the beneficial effect in the special subjects like patients from hypertension and diabetes in which 4-hydroxychloroquine therapeutic approach cannot be made. The study provides the scientific documentation of the role of the Ayurvedic formulation to combat COVID-19.
A quick laboratory method for assessment of blood penetration and splash resistance of PPE fabrics during the COVID-19 pandemic situation
Authors: Chaurasia R. K. , Yadav U. , Bhat N. N. , Sapra B. K.
Published: May 2020

In the current outbreak of COVID-19, healthcare facilities are hit by a shortage of supply of Personal Protective Equipments (PPE) owing to extensive local and global demands and restrictions on their import or export. To circumvent this, trials with several indigenous materials suitable to qualify for PPEs and sterilisation techniques for their reuse are being carried out. Prior to their commercialisation or reuse, it is imperative to evaluate the resistance of the PPE-fabrics against penetration of synthetic blood under applied pressure in the range of 40 - 300 mmHg as per test standards. Generally, two types of tests are recommended, namely, the Penetration Test and Splash Resistance Test, the former being more stringent. While the final certification of PPEs is carried out by authorised agencies, a first impression quick estimate of the choice of fabric can be made by using a simple laboratory set up. This study describes set ups developed in the laboratory to carry out these tests. Evaluation of the fabrics, post-gamma irradiation, was also carried out. Microscopic examinations were performed to investigate radiation induced structural changes in fabrics showing degraded performance. The developed set ups are useful for selection of fabrics and to assess the feasibility of reuse of PPEs, which is the need of the hour in this pandemic situation.
Psychological characteristics of educational stress of modern students
Authors: Dubczak Halina
Published: May 2020

The article presents the results of the empirical research of psychological characteristics of stress reactions that occur during educational activities of modern Ukrainian students. The analysis was performed on a group of 600 students (including 316 university students, 284 students of vocational schools; 283 men and 317 women) aged 15-45 years. Common and distinctive characteristics as for importance, levels, forms, dynamics and stress management techniques are determined for students of universities and vocational secondary schools. The conclusions are made about the need of organization of specifically targeted psychological work with students having high manifestations of educational and examination stress.
Building general competencies of social work students through experiential learning process
Authors: Gudinavičius Benas , Bubnys Remigijus , Šimaitytė Sandra
Published: May 2020

The article deals with the building of general competencies of social work students during the process of experiential learning. The article presents the analysis of a qualitative structured written reflections of social work students (N=11) and reveals which instrumental, interpersonal and systemic competencies of social work students were built while participating in the experiantal learning activities for one week.
Analysis of contexts of coping with occupational stress: subjective experiences of educational support and social welfare professionals
Authors: Alifanovienė Daiva , Gerulaitis Darius , Kepalaitė Albina , Šapelytė Odeta , Vaitkevičienė Asta
Published: May 2020

In the present article the impact of stress experienced by educational support and social welfare professionals on their professional activity and the opportunities of coping with it have been analysed applying a qualitative research approach. To analyse the subjective experience of educational support and social welfare professionals (N=27), a qualitative research approach has been chosen, the ontological basis of which consisted of the interpretive constructivist paradigm. The results of the research were validated using the expertise method: for external expertise the experts who did not participate in the research were employed, for internal expertise – persons who participated in the research and the researchers themselves. The data presented in the article are related both to the negative impact of stress on the professional activity and the positive impact leading to changes and improvement.
Relationship between job-related tension, negative affect at work and organizational culture
Authors: Karamushka Liudmyla , Tereshchenko Kira , Kredentser Oksana , Lazos Gelena , Karamushka Taras
Published: May 2020

This study explores relationships between job-related tension, negative affect at work and organizational culture in educational organizations. It has been found that teaching staff assess job-related tension and negative affect at work higher than educational organization managers do. It also has been shown that power culture contributes to increasing tension in educational organizations, while person culture and task culture as well as the strength of organizational culture contribute to reducing tension and negative affect at work in educational organizations.
A leitura literária na escola: ação e formação docente
Authors: Gonçalo Sheila Ferreira , Machado Ana Carolina , Monteiro Cícera Jéssica Paes Casarin , De Jesus Lizandra Bianchi , Pereira Manoela dos Santos
Published: May 2020

Esse relato de experiência discute as ações realizadas no âmbito do projeto de extensão “Leitura Literária na Escola: Ação e Formação Docente”, desenvolvido no Instituto Federal de São Paulo – Campos do Jordão. O projeto teve como objetivo aprimorar a formação inicial de professores, aprofundando seus conhecimentos referentes à didática envolvida na prática pedagógica de leitura de textos literários em sala de aula. Além disso, por meio de intervenções pedagógicas diferenciadas, o projeto buscou estimular o prazer pela leitura, atendendo alunos dos anos iniciais do Ensino Fundamental. Foram planejadas e aplicadas situações de intervenção, envolvendo a leitura de livros de literatura infantil, seguida de uma atividade relacionada ao enredo da história lida. O planejamento das intervenções e a atuação em sala de aula possibilitaram às extensionistas a análise reflexiva sobre a efetividade das estratégias didáticas propostas, viabilizando uma investigação de caráter didático.
MARKETING ANALYSIS OF THE ASSORTMENT OF DRUGS FOR THE TREATMENT OF HERPES VIRAL DISEASES AT THE PHARMACEUTICAL MARKET OF UKRAINE
Authors: Kienko Lydmila , Hrytsenko Vita , Iakovlieva Larysa , Bobrytska Larysa
Published: May 2020

Nowadays there is a tendency towards the spread of viral diseases that cause significant complications to human health. Therefore, the question of creating new drugs that have a high antiviral effect is topical.

The aim. To study the range of drugs in Ukraine for the treatment of herpes viral diseases.

Materials and methods. In the work were used the list of drugs from official sources of information, which were processed by methods of generalization, systematization, graphic, comparative and structural analysis.

Results and discussion. The marketing research of drugs for the treatment of herpes viral diseases presented at the pharmaceutical market of Ukraine has been conducted. According to the results it is found that 80 drugs for the treatment of herpes viral diseases of various dosage forms are presented in the domestic market, of which 70 % – tablets; 51 % – medicines produced by the industry of Ukraine; 94 % – are monocomponent preparations.

Soft drugs play important role in the treatment of skin diseases because they provide a direct effect of the drugs on the pathogens, eliminate inflammatory phenomena and eliminate or reduce the symptoms of the disease. Soft dosage drugs have practically no contraindications, they can be used at any age, regardless of the presence of comorbidities.

Conclusions. Domestic drugs (51 % of the total range) dominate in the market structure. The main part (94 %) consist of monocomponent preparations. The results of the research prove the relevance of the development of new combined soft dosage forms for the treatment of herpes viral diseases, which should be produced by the Ukrainian industry and satisfy the medical and economical needs of patients. The results of the marketing analysis show that it is relevant and promising to create new combined the soft dosage forms for the treatment of herpes viral diseases.
GENETIC (RAPD-PCR) VARIABILITY OF STAPHYLOCOCCUS AUREUS STRAINS EXTRACTED FROM LOCUS MORBI AND INTAKT SKIN OF PATIENTS WITH ALLERGODERMATOSIS
Authors: Pokhil Sergiy , Dzhoraeva Svetlana
Published: May 2020

The article presents data on the study of genetic relatedness of S. aureus strains growing on the skin and nasal passages of patients with allergodermatoses. A study of the possible correlation between the genotype of the pathogen and the burden of allergodermatoses using the RAPD-PCR method was done.

The aim of the research: determination by RAPD-PCR analysis (Random Amplified Polymorphic DNA) of genetic variability and affinity of S. aureus strains extracted from locus morbi, intact areas of skin and nasal mucosa of patients with allergodermatoses (AD and IE).

Materials and methods. RAPD-PCR was used to genotype 111 strains of Staphylococcus aureus extracted from the skin and nasal passages of patients with allergodermatoses (AD and IE), as well as 11 strains isolated from the skin of almost healthy individuals to identify genetic links between these strains. These strains were removed from patients with AD and IE who sought medical help in the dermatological department of the State Institution "Institute of Dermatology and Venereology of the National Academy of Medical Sciences of Ukraine" during 2016-2019.

Results. When comparing the RAPD spectra of strains extracted from the affected and intact areas of the skin of patients with mild and severe AD, the degree of genetic relatedness of the strains was 75.1±4.4 % and 98.8±0.8 %, (P˂0,001), respectively, indicating a high level of affinity of the strains. Strains of S. aureus removed from the nasal passages of patients with AD had a high level of genetic affinity with strains removed from the affected areas of the skin – 79.5±1.6 %, which indicates the auto-origin of strains growing on the skin of patients. The affinity of strains isolated from patients with IE with the reference culture of S. aureus ATCC 25923 was 27.4±1.8 % and 52.0±5.2 % for strains isolated from patients with AD, indicating their low genetic relatedness.

Conclusions. In the study of RAPD spectra of S. aureus strains isolated from patients with both AD and IE, no genotype was identified that would be associated with the disease or its severity. A high level of genetic affinity of strains extracted from locus morbi with strains extracted from the nasal passages of patients with AD, indicating the auto-origin of strains that grow on the skin of patients. It is shown that with increasing severity of AD, the genetic monotype of isolated pathogens increased: in patients with mild AD, 3 genetic clusters of the microorganism were identified, with moderate – 2, and with severe only one.
Beyond Artwashing: An Overview of Museums and Cultural Districts in Arabia
Authors: Elsheshtawy Yasser
Published: May 2020

In recent years many cities have a empted to integrate cultural developments within their overall planning strategy. Within the wider Arab region, the Gulf Arab states have been at the forefront of such developments, which they see as a way of diversifying their economies. Through such
initiatives the region is also se ing its sights on claiming the mantle as the Arab world's cultural leader. Large-scale institutions and the smaller spaces of art districts are seen as a way to modernize the Gulf states' local populations and integrate them within a wider cultural context.
Yet such approaches have risks such as gentrification and potential marginalization of a larger part of the population who may see themselves excluded from cultural spaces. This paper aims to unpack these issues by situating the development of spectacular museums ('big spaces') and art districts
('small spaces') in the Gulf region within a wider global context. It is structured in three parts. First, a theoretical exploration looks at the changing nature of museums in the twenty-first century, and the proliferation of art districts as a way of a racting creatives and spurring economic
and urban development. Second, the paper reviews the global spread of creative districts, distinguishing between planned and organic developments. The third and main part shifts the discussion to the Gulf Arab states, where the proliferation of museums and art districts is presented in more
detail, se ing their development within a wider context. The conclusion outlines a series of directives that could lead the Gulf to the forefront of an urban renaissance in the region. Yet for that to happen there needs to be a substantial shift in their overall planning paradigm, including
accounting for 'artwashing'.
Socially Engaged Art(ists) and the 'Just Turn' in City Space: The Evolution of Gwanghwamun Plaza in Seoul, South Korea
Authors: Choo Soyoon , Currid-Halkett Elizabeth
Published: May 2020

Expanding the critical research on the role of arts and artists in (influencing) urban development and urban planning tenets, this article looks at how the interventions of socially engaged art(ists) committed to creating momentum for a 'just turn' in civic values and action can have
tangible implications. We look into the threads of connection between the broader literature around the social and 'just turn' in the art world and urban planning approaches. Seoul is then presented with particular focus here as it is going through a watershed moment in what a city 'ought
to be', amid 'paradigm shifts' that involve rethinking the relational connection between the arts and city space in tandem with social engagement as the new doctrine of governance. The article focuses on the case of Gwanghwamun Plaza in central Seoul as an example that embodies these scenes
and changes. First, it goes over how the plaza's functions and image over time were influenced by both top-down and bottom-up dynamics, in the context of changing dynamics in the urban planning and art worlds. This leads on to more recent events such as the 2016–2017 'candlelight protests',
where socially engaged art(ists) played a bottom-up, pivotal role in (re)characterizing a tourism-booster landmark into a public space for social dialogue. By examining the built environment implications from these artistic interventions in Gwanghwamun Plaza, the article considers how the
practices and discussions from socially engaged art(ists) can be significant in characterizing the 'new normal' in the plaza's future and in urban/cultural policy and planning at large.
There's Music to Play, Places to Go, People to See! An Exploration of Innovative Relational Spaces in the Formation of Music Scenes: The Case of The Hague in the 1960s
Authors: Brandellero Amanda , Kloosterman Robert C.
Published: May 2020

It was not so much Amsterdam, the cultural capital, but The Hague which had the most vibrant Beat music scene in the Netherlands in the 1960s. Part of the explanation for this lies in the presence of a sizeable group of youngsters who were born in the former colony the Dutch East Indies
and who were already well acquainted with contemporary American popular music. This laid the foundation for the city's musical effervescence that contributed to placing it firmly on the map of the country's popular music history. We analyse the social and networked dimensions of this local
music scene by departing from Howard Becker's concept of art worlds and relating this to concrete places where key actors could meet. We show how abstract agglomeration economies touched down in The Hague and, to be more precise, in a selected set of venues and clubs. We thus present a micro
geography of innovative relational spaces where musicians, managers, gatekeepers and a motley crew of hangers-on met, exchanged knowledge, inspired and pushed each other to become (in cases even internationally) successful artists.
An economic view of the innovation potential, the tendencies of smoking in the developed countries and the importance of marketing in this field
Authors: Rigelsky Martin , Ivankova Viera , Gavurova Beata , Gonos Jaroslav
Published: May 2020

Smoking, as one of the main causes, is a negative factor associated with many diseases. The primary objective of the research is to determine the effect of innovation on selected smoking indicators in a sample of countries of the Organization for Economic Co-operation and Development (OECD). Four variables enter the analytical processing, such as Global Innovation Index, Population ratio of daily smokers (age 15+), Daily smokers (age 15-24), and Tobacco consumption in grams per capita (age 15+). These variables were included in the research from 2011 to 2018. The simple linear regression – the Ordinary Least Squares (OLS) model – and correlation analysis – Spearman’s rank correlation – was used for statistical processing. The results show that the effect of innovation on the ratio of daily smokers over the age of 15 to the total population may be considered a highly significant relationship. The effect on the annual tobacco consumption per capita is the second most significant relationship, and the effect on the ratio of daily smokers over 15 and under 24 years to the total population is the least significant compared to the previous two cases. Correlation analysis shows similar outputs. All these relationships may be considered negative. It is possible to talk about the lost innovation potential associated with smoking, primarily in the productive part of the population. A higher level of smoking can be associated with a lower level of innovation. Also, innovation negatively affects the tendency to smoke. Therefore, public policies should promote a healthy lifestyle.
AcknowledgmentsThis research is funded by the RVO 2020 internal grant scheme of the Tomas Bata University in Zlín titled “Economic quantification of marketing processes aimed at increasing value for the patient in the process of construction of system in order to measure and to manage performance in healthcare facilities in the Czech Republic.”
Differences in Sexual Function Between Trimesters During Pregnancy: An Observational Study
Authors: Soysal Sunullah , Sarioz Abdullah , Kilincdemir Turgut Umran , Anik Ilhan Gokce , Arman Yusuf , Yildizhan Begum , Pekin Tanju
Published: May 2020

OBJECTIVE: The aim of this study was to evaluate differences in sexual function between trimesters, and factors (in addition to pregnancy) that influence sexual function during pregnancy.STUDY DESIGN: This observational study was conducted at a tertiary referral center with 372 pregnant women. Seventy-two of the women did not complete the questionnaire (rejections or missing data) and the overall response rate was 80.6%. Among the remaining women, 43 of them excluded due to depression. Beck Depression Inventory was used to evaluate depression. Index of female sexual function questionnaire was used to assess sexual function. Index of female sexual function had a total and six sub-domain scores which assess the quality and frequency of sexual intercourse, desire, overall satisfaction, ability to achieve orgasm, and degree of clitoral sensation (c.sensation).RESULTS: Total index of female sexual function and quality, satisfaction, orgasm, and c.sensation sub-domain scores were lowest in the third trimester. Older age, lower level of education, and lower level of income negatively affected total index of female sexual function scores. Quality scores were lowest in older women and women with lower education. Frequency scores were highest during the second trimester. Desire scores were highest in women aged between 18 and 25 years, in women who were newly married (1-3 years), and during the second trimester. Satisfaction scores were lowest in women older than 35 years, and highest in newly married women. Orgasm scores were highest in women aged 18-25 years, in newly married women. CONCLUSIONS: Sexual function in women during the third trimester of pregnancy is generally affected negatively.
Inulin as a Delivery Vehicle for Targeting Colon-Specific Cancer
Authors: Chadha Swati , Kumar Arun , Srivastava Shambhavi Ashwini , Behl Tapan , Ranjan Rishu
Published: May 2020

Natural polysaccharides, as well as biopolymers, are now days widely developed for targeting colon cancer using various drug delivery systems. Currently, healing conformations are being explored that can efficiently play a multipurpose role. Owing to the capability of extravagance colonic diseases with the least adverse effects, biopolymers for site specific colon delivery have developed an increased curiosity over the past decades. Inulin (INU) was explored for its probable application as an entrapment material concerning its degradation by enzymes in the colonic microflora and its drug release behavior in a sustained and controlled manner. INU is a polysaccharide and it consists of 2 to 1 linkage having an extensive array of beneficial uses such as a carrier for delivery of therapeutic agents as an indicative/investigative utensil or as a dietary fiber with added well-being aids. In the main, limited research, as well as information, is available on the delivery of therapeutic agents using inulin specifically for colon cancer because of its capability to subsist in the stomach’s acidic medium. This exceptional steadiness and robustness properties are exploited in numerous patterns to target drugs securely for the management of colonic cancer, where they effectively act and kills colonic tumor cells easily. In this review article, recent efforts and inulin-based nano-technological approaches for colon cancer targeting are presented and discussed.
Evaluation of the Prevalence of Sleep Disorder Among Patients with Type 2 Diabetes Mellitus Referring to Ghaem Hospital from 2016 to 2017
Authors: Khorasani Zahra M. , Ravan Vahid R. , Hejazi Sepideh
Published: May 2020

Objectives:

Diabetes is the most common metabolic disease in primary health care. The
prevalence and severity of diabetes can be influenced through lifestyle modification. This study was
aimed to identify the prevalence of sleep disorders as a modifiable lifestyle factor among diabetic
patients.

Materials and Methods:

This cross-sectional study was conducted on 190 patients with type 2 diabetes
mellitus who referred to the Internal Medicine Clinic of the Ghaem Hospital, Mashhad, Iran from 2016
to 2017. A demographic questionnaire and the Pittsburgh Sleep Quality Assessment questionnaire (with
sleep disorder defined as scores higher than 5) was filled for each subject. Blood tests including
haemoglobin A1 C (Hb A1C), fasting blood sugar (FBS) and 2 hour post prandial glucose as well as the
assessment of blood pressure and body mass index (BMI) were performed for all patients. Data were
analysed using the statistical package for social sciences (SPSS) version 16.

Results:

Age of the patients (with male to female ratio being 71/119s) was 56.31 ± 7.37 years. BMI of
more than 25 kg/m2was observed in 145 (76.3%) of patients. Mean Pittsburgh Sleep Quality
Assessment score was 7.48 ± 4.11. Fifty-one (26.8%) patients were good sleepers and 139 (73.2%) were
poor sleepers. There was a significant relationship between sleep disorder and age (p=0.019) and female
gender (p=0.017), but no other variables which included level of education, occupation, HbA1 C, FBS,
2-hour post prandial glucose, systolic and diastolic blood pressure.

Discussion:

Sleep disorders are common among type 2 diabetic patients especially women. It is
recommended that sleep disorders should be screened in diabetic patients. Treatment and prevention of
sleep disorders through sleep hygiene education including recommendation to have normal nocturnal
sleep should be focused by practitioners in type 2 diabetic patients, especially women. Appropriate
measures should be taken to manage sleep disorders by weight control in this population.
Analgesic Equivalent Days:
A Novel Approach to Assess Chronic Analgesic Use in the Population
Authors: Ortiz Michael S.
Published: May 2020

Introduction:

There is no simple method to compare the use of multiple analgesic products in mild to moderate pain. The aim of this study is to validate a new tool to assess analgesic use.

Methods:

A measure of Analgesic Equivalent Days (AEDs) was developed using Defined Daily Doses (DDD) and the total mg of each analgesic over a 12 month period. Comparisons were made using analgesic class and all analgesics combined.

Results:

In a group of newly initiated patients with Osteoarthritis, AEDs values indicated that patients received around 70% of AEDs from paracetamol, 20% from NSAIDs and 10% from opioids. AEDs were similar between the two paracetamol formulations. However, one group took 8 more AEDs of NSAIDs, while the other group took 7 more AEDs of opioids.

Conclusion:

Even though the total AED scores, there was no significant difference in total analgesic use between the two formulations, differences were found among the analgesic classes. The AED methodology was sufficiently sensitive to demonstrate that one group of patients climbed higher up the analgesic ladder than the other group. AEDs are easy to calculate and seem to produce valid outcomes from both a statistical and a clinically meaningful perspective.
Investigating the Impact of Nature in Designing Cultural Environments for Children
Authors: Sadafi Nasibeh , Azhdari L.
Published: May 2020

There is a tendency to communicate with nature in human beings as a set of emotional experiences. This study investigates the impact of organic architecture in creating cultural spaces for children. The concepts of nature, naturalist architecture and children educational psychology, from the perspective of scholars and researchers in this area are investigated. The children’s perception of nature and their feelings were assessed and one hundred forty respondents among the instructors of cultural centres in different regions of Tehran have answered the questionnaires. To investigate the hypotheses, Univariate T - test and F - test were applied. The results showed that the stimulation of the natural environment has a positive and meaningful effect on curiosity, participation, and fantasy in children, while they show their impressions of nature indirectly. Therefore, designing applicable spaces according to children’s physics, using appropriate colours and furniture as well as more environmentally-related spaces, can have positive effects on social participation, intuitive and verbal skills of the children.
X/Y EMBERKÉP HATÁSA A TELJESÍTMÉNYRE VÁLTOZÓ KÖRNYEZETBEN
Authors: Filep Roland
Published: May 2020

A vezetési stílus kérdésköre kutatott terület, több elmélet és modell is született az elmúlt évtizedekben, ezek közül az egyik legismertebb a McGregortól származó X/Y elmélet, amely nagy múltra tekint vissza, mégis máig foglalkoztatja a kutatókat. Az utóbbi években számos olyan elemzés is megvalósult, amely a stílusnak a szervezeti teljesítményre gyakorolt hatását vizsgálta objektív vagy szubjektív mutatók használatával. Ebben a munkámban az X/Y elmélet alapjainak, a családi vállalkozások meghatározásának és a teljesítménymérésre tett legutóbbi kísérleteknek a rövid áttekintésén túl családi vállalkozások vezetőinek körében végzett empirikus kutatásomat mutatom be. A kutatási kérdéseimmel (K1, K2) arra kerestem a választ, hogy van-e összefüggés a vezető McGregor-i emberképe és a vállalkozás teljesítménye között. A teljesítmény mérőszámaként korábbi kutatások nyomán objektív számviteli adatot, az értékesítés nettó árbevételét vettem alapul, a 2008-as gazdasági válság idején a vállalkozók vezetői is elsődlegesen ebben – az értékesítési forgalom változásában – mérték a válság hatásait. A korábbi, X/Y emberkép hatásait vizsgáló kutatások a válság lehetséges befolyásoló hatásait nem vették figyelembe, indokolt lehet ilyen tekintetben is elemzéseket végezni, ezért az első kérdésemben (K1) az X/Y emberkép és a 2008/2012 -i teljesítmény közötti összefüggést vizsgáltam, ezzel lehetőségem nyílt a 2008-as gazdasági válság induláskori (2008) és a vezetők előzetes várakozása szerint fellendülést hozó 2012-es év teljesítményének összevetésére. A kapott eredmények a korábbi kutatási eredményekhez hasonló képet mutatnak, az Y elmélet képviselői eredményesebbek, amelyet a kereszttábla-elemzés szignifikáns eredményei is megerősítettek. Második kérdésemben (K1) a gazdasági válság időszakának átugrásával a K1-hez képest más időhorizonton (2008/2017) vizsgáltam meg az X/Y elmélet szerinti lehetséges összefüggést. Ez utóbbi (K2) esetben a K1-től eltérően statisztikailag nincs kimutatható összefüggés a változók között, viszont az arányok arról tanúskodnak, hogy az Y emberképpel rendelkezők ebben az időtávban is sikeresebbek forgalomnövelés tekintetében. Az attitűdök nagyon nehezen formálhatók, viszont az X emberképpel rendelkező vezetőknek érdemes lehet felülvizsgálni az emberekről alkotott vélekedésüket, változtatni a hozzáállásukon, mert az eredményekből kitűnik, hogy mérhetően sikeresebb az, aki Y emberképpel rendelkezik. A vállalkozások többségénél aktuálissá váló generációváltás esetében a kapott eredmények tükrében azt is érdemes megfontolniuk a stafétát átadó vezetőknek, hogy milyen emberképpel rendelkező utódra bízzák a vállalkozás további irányítását.
Online self-learning
Authors: Ádámkó Éva
Published: May 2020

In this paper four short sessions are reviewed in the theme of introductory programming. The sessions were performed in four different student groups from the age twelve to seventeen in two different schools. The paper summarizes important input and output properties of the groups, like the preliminary studies of Informatics and the grades in both Informatics and Mathematics – if available – also the results of the learning process during the sessions. The focus is on the skills of programming and self-learning, and the differences of it in respect to the age, the gender and the preliminary studies.
A digitalizációs folyamat az agrárvállalatok körében, avagy egy kérdőíves kutatás eredményei
Authors: Szabóné Berta Olga , Juhász Csilla
Published: May 2020

Az „információs társadalom” kifejezés az 1960-as évek elejének japán társadalomtudományában jelent meg először (Z. Karvalics, 2007). Jelentős változáson ment át a fogalom értelmezése az elmúlt évtizedek alatt, ami mutatja, hogy a dinamikusan fejlődő társadalmak az információ rohamos fejlődésének, az információgazdálkodásnak és a digitális világ dinamizmusának köszönhetően folyamatos változás alatt állnak. Az információ és az informatika szoros kapcsolata és összefüggése alapvető tényező lett a mai kor társadalmaiban, a szervezetek életében, amely megkerülhetetlen, olykor komoly vitákat és mély változásokat generál. A gazdasági szereplőknek szükségszerűen rugalmasnak kell lenniük a technológiai változásokkal szemben. Elég az ipari forradalom idejére gondolnunk, amikor a modern szövőgépek ellepték a gyárakat. Ellenkező esetben a változásnak ellenálló, rugalmatlan szervezet nem marad fenn a fejlődő és folyamatosan változó, dinamikus gazdasági környezetben. Természetesen igaz ez a mezőgazdaság esetében ugyanúgy, mint más nemzetgazdasági ágazatoknál. Feltételezésem, melyek alapján a kérdőívemet összeállítottam egyrészről az volt, hogy vállalatirányítási rendszereket a tevékenység diverzifikáltságával növekvő mértékben használnak a vállalkozások a mezőgazdaságban. Ugyanakkor úgy véltem, hogy a vállalkozás mérete is befolyással lehet az információs technológia (továbbiakban IT) használatára, így reméltem, erre vonatkozóan is egyértelmű adatokkal szolgál majd a kutatásom.
A kiegészítő melléklet információtartalmának összehasonlítása az információ-technológiai szolgáltatás és a sporttevékenység körében
Authors: Kerezsi Dóra
Published: May 2020

Napjainkban a számviteli beszámoló az egyik fontos információs forrás a vállalatok közötti gazdasági kapcsolatokban. Két alapvető részéből, a mérlegből és az eredmény-kimutatásból, azok aggregált jellegéből adódóan, akkor lehet a szükséges információhoz jutni, ha a harmadik része, a kiegészítő melléklet tartalmazza azokat az információkat, amelyek hozzájárulnak a beszámoló jobb értelmezéséhez. Ezen túl a kiegészítő mellékletnek segítenie kell a megbízható és valós összkép jobb bemutatását. A kiegészítő mellékletben a közlendő információk mélysége, részletezettsége nincs konkrétan megfogalmazva, ezért ezek szakmai mérlegelése az adott vállalkozásra van bízva. Alapvető célkitűzésem, hogy bemutassam milyen hasonlóságok és különbségek figyelhetők meg az információ-technológiai szolgáltatást végző és a sporttevékenységet folytató vállalkozások kiegészítő mellékleteinek információtartalmában. Szövegbányászat segítségével azt vizsgáltam, hogy milyen mértékben felelnek meg a törvényi előírásoknak.
Járműveknél fellépő veszteségforrások elemzése
Authors: Pálinkás Sándor , Juhász György , Szodrai Ferenc
Published: May 2020

A jármű üzemanyag fogyasztását jelentős mértékben befolyásolják a különböző veszteségek, ilyenek a gépjárműben keletkező veszteség (pl. csapágy veszteségek, a hajtásban, hajtóműben keletkező veszteségek stb.), a légellenállás vagy a gumiabroncsok gördülési ellenállása. Fontos tény, hogy üzemanyag-megtakarítást csak az üzem közben létrejövő veszteségek csökkentésével lehet elérni.

Kutatómunkánk célkitűzése, hogy definiáljuk a járművekben fellépő veszteségeket és azok meghatározási módszereit. A későbbiekben az így meghatározott értékek bemenő adatként fognak szolgálni járműenergetikai számítások modellezésénél.
Design of Chip Conveyor
Authors: Szabó Kristóf
Published: May 2020

The following article examines the design methodology of screw conveyors. The most significant steps are discussed concerning the design of the apparatus and its use in machine tools as a service component is explained.
Effect of the Friction Coefficient on Clinch Joints
Authors: Jónás Szabolcs , Tisza Miklós
Published: May 2020

In this study the effect of the friction coefficient on the clinch joints was examined in experimental and numerical way also. The knowledge of the frictional behaviour during the mechanical joining (i.e. clinching) is important from the point of view of resultant geometry which is related to and influence the strength of the joints, and furthermore the maximal forming force is limited by the tool’s failure load which can be reach with a non-favourable frictional condition, as well the aesthetic aspect are also has an importance in some special cases (e.g. in automotive industry).
Review of Modern Vehicle Powertrains and Their Modelling and Simulation in MATLAB/Simulink
Authors: Szántó Attila , Szíki Gusztáv Áron
Published: May 2020

Thanks to technological advances and environmental standards, as well as changing usage patterns, road vehicles are constantly developing. Electric and hybrid vehicles are playing an increasingly important role in today’s road transport. The most significant changes are probably in the powertrain of vehicles. The efficiency of internal combustion engines increases while their emissions continue to decline. In addition, high performance electric motors, batteries and even fuel cells play an increasingly important role in hybrid and electric vehicles. In this publication, we review the drive systems of current modern vehicles and the types and characteristics of their major components. We also review the available models and computer programs for their simulation, focusing mainly on MATLAB/Simulink applications. Based on this, we can develop our own models and simulation programs which will help us to perform different driving dynamics simulations and to compare the performance, dynamic and energetic characteristics of these powertrains and their components to each other.
Tehergépjárművek menetadatainak elemzése egy meghatározott szállítási útvonalon
Authors: Czégé Levente , Vámosi Attila , Kocsis Imre
Published: May 2020

Ebben a tanulmányban egy állandó útvonalon közlekedő tehergépjármű mozgását leíró menetciklus létrehozását tárgyaljuk. Kiválasztottunk egy jellemző szállítási útvonalat, ahol olyan tehergépjárművek közlekednek, melyek fel vannak szerelve megfelelő adatgyűjtő berendezéssel. Hosszú távon gyűjtöttük a jármű mozgását leíró adatokat, majd az adatokat egy saját fejlesztésű célszoftver segítségével szűrtük és készítettük elő, végül a tisztított adatokat statisztikai eljárások alkalmazásával dolgoztuk fel.
Application of Additive Technology in Precision Casting
Authors: Halápi Dávid , Varga László
Published: May 2020

In this paper the surface of the prepared test specimens had been examined with light microscopy and surface roughness measurements. In order to improve the surface smoothness of PLA specimens, application of ethyl acetate was required. After this surface treatment, microscopic images were taken again. The melting and decomposition temperatures of the materials had been determined using derivatography. The chosen method was precision casting with gypsum molding. Also, the plaster molds had been burnt out according to the predefined melting and firing diagram. The measurement series shows that the samples produced by 3D printing can also be used in the field of precision casting. They provide greater freedom of design, more sophisticated pieces, and prototypes can be finished in a shorter amount of time.
As deusas celtas e a jornada simbólica da alma feminina
Authors: Faro Mayra
Published: May 2020

Este artigo visa a apresentar uma análise arquetípica dos mitos de cinco deusas da mitologia celta, que refletem aspectos simbólicos e profundos da alma feminina, contribuindo dessa forma com o processo terapêutico e de individuação das mulheres. As antigas histórias míticas, permeadas de símbolos, ressoam por milênios nas culturas humanas, no imaginário e no folclore. Observa-se nos antigos mitos celtas um vasto e profundo material simbólico sobre a psique humana. Ao contrário da mitologia greco-romana, que é bastante divulgada e foco de amplas pesquisas, a mitologia celta ainda é pouco investigada. Assim, este artigo intenta contribuir com os estudos sobre a mitologia celta, no campo da psicologia analítica, tecendo diálogos com as ciências das religiões e a fenomenologia. Para tanto, foram analisadas cinco deusas celtas: Danann, Brighid, Macha, Cailleach e Cerridwen. A abordagem do trabalho foi qualitativa e fenomenológica, com pesquisa bibliográfica, pautando-se nos estudos de C. G. Jung, Jacobi, Mircea Eliade, Clarissa P. Estés e outros.
Citizen-Patient Involvement in the Development of mHealth Technology: Protocol for a Systematic Scoping Review
Authors: Bjerkan Jorunn , Kane Bridget , Uhrenfeldt Lisbeth , Veie Marit , Fossum Mariann
Published: May 2020

Background

The development of mobile technology for information retrieval and communication, both at individual and health organizational levels, has been extensive over the last decade. Mobile health (mHealth) technology is rapidly adapting to the health care service contexts to improve treatment, care, and effectiveness in health care services.

Objective

The overall aim of this scoping review is to explore the role of citizen-patient involvement in the development of mHealth technology in order to inform future interventions. By identifying key characteristics of citizen-patient involvement in system development, we aim to improve digital communication and collaboration between health care providers and citizen-patients, including sharing of health care data.

Methods

The systematic scoping review will follow the Joanna Briggs Institute methodology for scoping reviews by searching literature in 3 steps. We will include literature reporting on the public, citizens, and patients participating in the development of mobile technology for health care purposes in MEDLINE, CINAHL, Scopus, EMBASE, and ProQuest Dissertations and Theses. A preliminary search was completed in MEDLINE and Scopus. The screening process will be conducted by 2 of the authors. Data will be extracted using a data extraction tool prepared for the study.

Results

The study is expected to identify research gaps that will inform and motivate the development of mHealth technology. The final report is planned for submission to an indexed journal in November 2020.

Conclusions

To our knowledge, this review will be the first review to provide knowledge about how citizen-patients participate in system developments for mHealth tools and the value that such involvement adds to the system development process.

International Registered Report Identifier (IRRID)

PRR1-10.2196/16781
A Digital Substance-Use Harm Reduction Intervention for Students in Higher Education (MyUSE): Protocol for Project Development
Authors: Dick Samantha , Vasiliou Vasilis S , Davoren Martin P , Dockray Samantha , Heavin Ciara , Linehan Conor , Byrne Michael
Published: May 2020

Background

Digital interventions have been identified as a possible tool for reducing the harm caused by illicit drug use among students attending higher education (ie, college students). However, the success of interventions in this area has been hampered by a lack of user involvement and behavior change theory in their design. The My Understanding of Substance use Experiences (MyUSE) project combines a rigorous user-centered design (UCD) methodology and a robust behavioral change framework to develop a digitally delivered harm reduction intervention for illicit drug use among students in higher education.

Objective

This project aims to design and develop a digital intervention that targets drug use–related harm among students in higher education.

Methods

The MyUSE project will take place over 3 phases. The first phase was exploratory in nature, involving 3 systematic reviews, a large survey, and student workshops to gather a comprehensive evidence base to guide the project. The second phase is the development stage of the project, involving the use of the Behavior Change Wheel theoretical framework to determine the behavior change techniques of the intervention and the use of the UCD methodology to guide the development of the digital intervention. The third phase is the evaluation stage, whereby the intervention will undergo a 5-stage evaluation process to comprehensively evaluate its impacts.

Results

The exploratory phase 1 of the MyUSE project was completed in December 2018. Phase 2 is currently underway, and phase 3 is due to begin in September 2020.

Conclusions

Higher education institutions (HEIs) are ideally placed to intervene and support students in the area of illicit drug use but are constrained by limited resources. Current digital interventions in this area are sparse and have several weaknesses. The MyUSE project combines a UCD approach with a robust behavior change framework to develop a digitally delivered intervention that is economically viable, effective in changing behavior, usable and acceptable to students, and able to sustain long-term implementation in HEIs.

International Registered Report Identifier (IRRID)

DERR1-10.2196/17829