bluuebunny/crossref_metadata_2025 huggingface dataset:
Case Report: Diagnosis and Management of Body Stalk Anomaly
Authors: Yunitra Imelda , Yusrawati Yusrawati
Published: April 2024

Background: Body stalk anomaly is a rare and severe malformation syndrome , occurring only 1 of 10.000 live births. The patholphysiology and trigger factor of body stalk anomaly are still unknown and characterized by : abdominal wall defects, thoracoo and abdominochisis, Severe kyphoscoliosis, a truncated or absent umbilical cord, and limb irregularities are characteristic features of body stalk anomaly. Potential factors contributing to this condition encompass early amnion rupture due to direct mechanical pressure or the presence of amniotic bands, vascular disruption in the early embryo, or an abnormality in the germinal disk.Early antenatal diagnosis is crucial for patient management despide the low life expectancy, and cooperative teamwork is needed to investigation the abdnormalities encountered at birth. the chromosomal testing is performed for congemital anomaly investigation. Case Presentation: We describe a case of body stalk anomaly that was identified through antenatal ultrasound evaluation during the initial visit. The findings were confirmed during the fetomaternal ultrasound examination, the finding were as follows : a single live fetus in utero in transverse lie position, absent amniotic fluid, scoliosis of the vertebrae, an abdominal wall defect, visceral organs (liver and intestines) protruding from the defect. The patient underwent elective caesarean section due to the tranverse lie positionof the fetus and severe oligohydramnios. The baby was born weigh in 2700 grams, measuring 30 cm in length, and with apgar score of 1/1. The observed congenital anomaly include : the placental adhering to the fetal abdomen, absence of an umbilical, visceral organs ( liver, spleen, small intestine, and large intestine ) protruding from a large abdominal wall defect. Both upper limbs are normal , the right lower limb has short femur with tibia and fibula, four toes and a band from the right foot to the pelvis. The left limb is not formed, with low set ears, placental thicketing, a singke umbilical artery, and undeveloped anus. Conclusion: Ultrasound examination is primary diagnostic tool to detect Body Stalk Anomaly ( BSA) ,with ultrasound , doctors can visualize the internal structure of the fetus and conditions intra uterine. Diagnosis of chromosomal abnormalities in fetus is one of most important challrnge in perinatology.
The Effect of Lemon Skin Extract on Uric Acid Levels of Hyperuricemia Male Wistar Rats
Authors: Ardiansyah Revi , Wijayahadi Noor , Mahati Endang , Nindita Yora
Published: April 2024

Background: Purine metabolism, carried out in the liver, results in the production of uric acid. Hyperuricemia is a condition of elevated level of uric acid in the blood that can lead to gout if untreated. Lemon (Citrus Limon.) contains flavonoids which act as antioxidants and have the potential role as antihyperuricemia. Aim: To determine the effect of lemon peel extract on uric acid levels. Methods: Thirty-six male wistar rats from Farmhouse Ungaran were randomly divided into 6 groups, consists of healthy control group (K0), hyperuricemic control (K1), allopurinol control (K2), and 3 treatment groups (P1, P2, P3). Hyperuricemia induced with administration of block broth and potassium oxonate for 4 weeks. Lemon peel extract doses of 17,5, 35, and 70 mg/kg BW, and allopurinol 90 mg/kg BW was given orally for 2 weeks. Statistical analysis was conducted to evaluate differences among groups before and after the intervention. Results: There was a significant difference (p<0,05) in uric acid levels before and after intervention of lemon peel extract in groups K1, K2, and P3. Meanwhile, in groups K0, P1, and P2, there were no significant differences observed. In the pre-test uric acid levels, there was a significant difference (p<0,05) between the K0 group and K1, K2, P1, P2, and P3. Conclusion: There were no significant differences observed in the uric level acid of the treatment and control group after intervention, but there were significant differences in the effects of graded dosages between the treatment groups.
Strategi Partai Baru: Partai Gelombang Rakyat Indonesia Menuju Elektoral 2024
Authors: Nugraha Tian Adhia , Mukti Hening Ginanjar
Published: April 2024

Studi ini berupaya untuk memahami strategi yang dilakukan oleh Partai Gelombang Rakyat (Gelora) sebagai partai baru dalam pemilihan umum 2024 di Indonesia. Sebagai partai baru, Partai Gelora perlu memiliki strategi untuk berkontestasi dengan partai-partai besar di Indonesia. Untuk menganalisis strategi yang dilakukan oleh Partai Gelora, penulis menggunakan kerangka teori Lucardie (2000) dalam menganalisis partai baru dan Mietzner (2008) untuk melihat kondisi kepartaian di Indonesia. Studi ini menggunakan metode kualitatif untuk mendalami strategi yang dilakukan oleh partai politik baru yaitu Partai Gelombang Rakyat (Gelora) Indonesia. Penulis menemukan bahwa Partai Gelora berkontestasi dan berkompromi dengan partai lain sebagai strategi untuk memenangkan suara pada Pemilu 2024 di Indonesia. Partai Gelora menantang ideologi partai sebelumnya yang cenderung agamis dengan membawa ideologi baru yaitu nasionalis. Strategi Partai Gelora menyesuaikan dengan kondisi elektoral Indonesia yang menunjukkan arah yang sentripetal. Hal ini ditunjukkan melalui strategi yang dilakukan Partai Gelora dengan melakukan kompromi dengan partai lain dalam pemenangan pemilu. Sebagai partai baru, Partai Gelora menggunakan strategi catch-all party, strategi tersebut dilakukan guna memperoleh basis pemilih dalam pemilihan 2024. Strategi catch-all menjadikan Partai Gelora mencairkan basis ideologi yang bertujuan untuk menjadikan Partai Gelora lebih inklusif.
Responsivitas Pelayanan Dinas Pemberdayaan Perempuan, Perlindungan Anak, dan Masyarakat Kota Binjai dalam Mengatasi Kekerasan di Kota Binjai
Authors: Naufal Muhammad Fari , Siahaan Asima Yanty Sylvania
Published: April 2024

Responsivitas pelayanan merupakan suatu hal yang penting bagi pemerintah untuk mewujudkan pemenuhan kebutuhan kepada masyarakat dengan tepat dan jelas, termasuk menyangkut perlindungan terhadap perempuan dari tindak kekerasan. Namun, daya tanggap dari pemerintah masih belum maksimal dalam mengatasi kekerasan terhadap perempuan yang terlihat dari kurangnya sosialisasi dan edukasi terkait kekerasan terhadap perempuan dan layanan yang ada, kurangnya fasilitas, serta kurangnya ketanggapan dari layanan penanganan yang bekerja sama dalam menangani kasus. Penelitian ini bertujuan untuk mendeskripsikan secara mendalam mengenai responsivitas pelayanan Dinas Pemberdayaan Perempuan, Perlindungan Anak, dan Masyarakat Kota Binjai dalam mengatasi kekerasan terhadap perempuan di Kota Binjai. Metode yang digunakan dalam penelitian ini adalah kualitatif deskriptif dengan feminist research. Hasil dari penelitian menunjukkan bahwa pemerintah cukup baik dalam memberikan layanan perlindungan terhadap perempuan, namun kurang dalam penguatan tindakan prenventif. Hal tersebut dapat terlihat dari availability (ketersediaan) dimana pemerintah menyediakan layanan jasa dan fasilitas melalui UPTD PPA. Layanan dan fasilitas tersebut dapat mudah diakses melalui perpanjangan tangan kelurahan yang dapat dilihat dari karakteristik aksesibilitas. Dalam pelaksanaan pelayanan, pemerintah sudah berkomitmen menanamkan sikap simpati, empati, serta peka terhadap kebutuhan perempuan korban kekerasan yang merupakan karakteristik dari penerimaan. Terakhir, pengembangan layanan juga dilakukan dengan menyediakan layanan berbasis aplikasi seperti SiAP KaPAn aja maupun pengadopsian peraturan baru yang termasuk dari adaptasi pemerintah pada era globalisasi.
Meninjau Eksistensi Kebijakan Pemerintah Terhadap Kerentanan Cyber child grooming
Authors: Ishmah Nadhilah , Putri Anggi Fransiska , Sicillia Edna , Arimbawa Ni Putu Vania Leonyta Putri , Ramadhana Aditya Yuda
Published: April 2024

Riset ini merupakan studi kebijakan untuk menelisik peran pemerintah terhadap kerentanan kekerasan seksual di ranah digital. Tingginya penggunaaan internet oleh anak terutama sejak masa pandemi Covid-19 menciptakan sebuah fenomena kejahatan baru bernama cyber child grooming, yakni sebuah fase pendekatan secara emosional dengan seorang anak melalui internet. Kota Semarang yang memeroleh predikat kota tertinggi untuk kekerasan seksual anak di Jawa Tengah menjadi lokus riset ini. Dalam menganalisis kebijakan kasus cyber child grooming di Kota Semarang, digunakan metode kualitatif untuk mendapatkan data secara komprehensif melalui reduksi data, penyajian data, dan verifikasi yang didapat melalui wawancara mendalam semi terstruktur dengan Pemerintah Kota Semarang dan LSM. Riset ini menemukan bahwa Pemerintah Kota Semarang sampai saat ini belum memiliki kebijakan khusus mengenai kekerasan seksual berbasis elektronik. Penanganan kekerasan seksual berbasis elektronik hanya berlandaskan pada UU Pornografi, UU TPKS, dan UU ITE. Hal ini berdampak pada proses penanganan cyber child grooming yang tidak maksimal, sebab kekerasan seksual berbasis elektronik hanya dapat ditangani apabila korban divisum dan konten seksual telah disebarkan. Hal ini menjadi tidak relevan ketika cyber child grooming merupakan proses awal dari kekerasan seksual yang memengaruhi anak secara psikologis. Upaya Pemerintah Kota Semarang melalui sosialisasi dan penyuluhan belum mampu menjangkau substansi masalah karena belum disertai kebijakan yang bisa melindungi anak secara hukum serta memberikan efek jera bagi pelaku.
Cytotoxic and phytochemical screening of Solanum lycopersicum–Daucus carota hydro-ethanolic extract and in silico evaluation of its lycopene content as anticancer agent
Authors: Ademosun Olabisi Theresa , Agwamba Ernest C. , Ahmad Iqrar , Patel Harun , Louis Hitler , Adebayo Abiodun Humphrey , Ajanaku Kolawole Oluseyi
Published: April 2024

This article explores the potential of a specific functional food mix containing lycopene, a pigment found in tomatoes, for its role in cervical cancer prevention and treatment. The article assesses the cytotoxic effects on cervical cancer cells and conducts molecular docking analysis to understand the biological activities and binding interactions of lycopene. The formulations are analysed for their phytochemical profile, and their in vitro antioxidant activities are evaluated using spectrophotometric methods. Cytotoxicity tests on cervical cancer cells demonstrate that the ethanol extract of tomatoes exhibits the highest cytotoxic inhibition (40.28%), while carrots show minimal cytotoxic effects. Moreover, the lycopene extract exhibits dose-dependent cytotoxicity, with the highest concentration (1,000 µg/mL) displaying remarkable inhibition (74.2%). Molecular docking analysis indicates favourable interactions between lycopene and the pro-apoptotic protein BAX 1, suggesting its potential to induce apoptosis in cervical cancer cells, but camptothecin demonstrated stronger interactions. Molecular dynamics simulations confirm the stability of lycopene–protein complexes throughout the 100 ns simulation, supporting their potential as anticancer agents. Overall, the study highlights the cytotoxic effects of tomato–carrot food extracts and lycopene on cervical cancer cells. Molecular docking reveals the potential of lycopene to induce apoptosis through interactions with BAX 1. The stability analysis of lycopene–protein complexes further supports its anticancer properties. These findings enhance our understanding of the molecular mechanisms underlying the anticancer effects of lycopene and provide insights for future research on novel chemopreventive strategies for cervical cancer. However, further in vivo and clinical studies are warranted to validate the efficacy and safety of lycopene-based interventions.
Protective activities of silver nanoparticles containing Panax japonicus on apoptotic, inflammatory, and oxidative alterations in isoproterenol-induced cardiotoxicity
Authors: Xu Xiao , Diao Zhipeng , Zhao Bo , Xu Huajuan , Yan Shuying , Chen Huilin
Published: April 2024

Panax japonicus has long been utilized as an herbal remedy in Chinese traditional medicine for treating various diseases. In this investigation, we present the environmentally friendly silver nanoparticle (AgNP) synthesis by the aqueous extract of P. japonicas to follow its cardioprotective effects. Through various analytical methods, we identified the nanoparticles (NPs). Our XRD findings revealed the formation of Ag@P. japonicus, while FE-SEM imagery indicated a spherical shape, with NPs measuring less than 40 nm. The UV–Vis and FT-IR spectroscopy confirm the green synthesis of Ag@P. japonicus. In the medicinal section, 45 Wistar rats were utilized. These groups consisted of a normal group, a group that was solely treated with isoproterenol for inducing myocardial infarction, and two groups that were pretreated with AgNPs at different doses for 14 days. These pretreated groups were then challenged with isoproterenol. The expression of PI3K/Akt/mTOR and other downstream inflammatory and apoptotic mediators were followed. Additionally, the expression of Keap1, Nrf2, ECG, cardiac markers, and other downstream antioxidant enzymes were assessed. Treatment with AgNPs ameliorated the apoptosis, inflammation, and myocardial autophagy, regulated the PI3K/Akt/mTOR pathway, increased the antioxidant enzyme efficacies, and activated the Keap1/Nrf2/HO-1 pathway. The findings suggest that AgNPs may have a cardioprotective efficacy on myocardial infarction by mitigating the Keap1/Nrf2 pathway, GST, GPx, GSH, SOD, IL-1β, IL-6, TNF-α, NF-κB, Bax, Bcl2, caspase-9, caspase-3, and PI3K/Akt/mTOR pathway. Furthermore, the treatment decreased the infarct region size, attenuated the cardiac indicators levels, and mitigated immune cell infiltration and myocardial necrosis.
Experimental investigation of dynamic soil properties for modeling energy-absorbing layers
Authors: Abood Ahmed Salah , Fattah Mohammed Y. , Al-Adili Aqeel
Published: April 2024

Modeling the propagation of waves in geomechanics is an essential part of dynamic analysis. In geotechnics, the study of the interaction between the soil and the foundation is particularly interesting. In order to mimic low-speed operating types (less than 1,500 rpm), this study details the creation of a dependable and efficient approach for designing and fabricating the steel box container. When employed as a boundary, an absorbing layer drastically reduces the amount of wave reflection that occurs inside the limited region. The present effort is split into two halves. The first step is to calculate the damping layer’s damping constants, subgrade response modulus, damping ratio, shear modulus, vibration amplitude, and resonant frequency. The second section focuses on the dynamic study of the circular foundation by measuring the vibration amplitude, acceleration, velocity, and displacement caused by harmonic vibration machines. The findings demonstrate that simple material borders prevent the wave from dissipating as a consequence of reflection. Attenuation of waves is possible when the absorbing layer of energy represents semi-infinite soil. When absorbing just one layer, the vertical displacements at positions located at the box side boundary and its base decreased by 65, 63, and 67%, respectively. However, it dropped by 97, 96, and 98%, respectively, when two absorbent layers were used. On the basis of these promising results, the model results were compared with and without the absorbing layer. It would appear that the modeling of the absorbing layer, which is designed as two layers, has been satisfied for low speeds of harmonic vibration.
On projections of the tails of a power
Authors: Corson Samuel M. , Shelah Saharon
Published: April 2024

Let 𝜅 be an inaccessible cardinal, 𝔘 a universal algebra, and

∼

\sim

the equivalence relation on

U
κ

\mathfrak{U}^{\kappa}

of eventual equality.
From mild assumptions on 𝜅, we give general constructions of

E
∈
End

(

U
κ

/
∼
)

\mathcal{E}\in\operatorname{End}(\mathfrak{U}^{\kappa}/{\sim})

satisfying

E
∘
E

=
E

\mathcal{E}\circ\mathcal{E}=\mathcal{E}

which do not descend from

Δ
∈

End
⁡

(

U
κ

)

\Delta\in\operatorname{End}(\mathfrak{U}^{\kappa})

having small strong supports.
As an application, there exists an

E
∈
End

(

Z
κ

/
∼
)

\mathcal{E}\in\operatorname{End}(\mathbb{Z}^{\kappa}/{\sim})

which does not come from a

Δ
∈

End
⁡

(

Z
κ

)

\Delta\in\operatorname{End}(\mathbb{Z}^{\kappa})

.
Effect of heat treatment on the microstructure and mechanical properties of biocompatible Ti–Ta–Nb–Zr alloys prepared by selective laser melting
Authors: Zhang Kai , Zhong Ning , Zhang Xianjin , Wen Chen , Zhou Yun , Lu Shangwen
Published: April 2024

In this paper, a low elastic modulus, non-cytotoxic Ti-10Ta-2Nb-2Zr titanium alloy was prepared by selective laser melting additive manufacturing. The effect of annealing and solution heat treatment on the structure, mechanical properties, and tribological behavior were investigated. The results show that the microstructure was composed of the main α′ phase and a small amount of β phase. Heat treatment improved strength and elongation. The ultimate tensile strength (UTS) and elongation of the deposited specimen were 807 ± 8.74 MPa and 6.6 ± 0.75 %, respectively. After annealing, the UTS was nearly the same, but the elongation increased to 15.3 ± 0.95 %. After solution and aging, the UTS and elongation increased to 873 ∼ 813 MPa and 9.25–11.9 %, respectively. The elastic modulus of the deposited specimen was 120 ± 6.81 GPa. The elastic moduli of heat treated specimens ranged from 74 ± 4.04 to 96 ± 5.13 GPa. The elastic moduli of heat treated specimens were close to that of β-type titanium alloys. The wear mechanism was mainly abrasive wear and oxidative wear. Compared with the deposited and annealed specimens, the solution and age treated specimens had low friction coefficients and much better wear resistance. In terms of properties and cost, the designed alloy has great potential in the medical implant field.
Some transforms, Riemann–Liouville fractional operators, and applications of newly extended M–L (p, s, k) function
Authors: Ayub Umbreen , Mubeen Shahid , Abbas Amir , Khan Aziz , Abdeljawad Thabet
Published: April 2024

There are several problems in physics, such as kinetic energy equation, wave equation, anomalous diffusion process, and viscoelasticity that are described well in the fractional differential equation form. Therefore, the solutions with elementary solution method cannot be solved and described deliberately with detailed physics of the problems, so these problems are solved with the help of special operators such as Mittag–Leffler (M–L) functions equipped with Riemann–Liouville (R–L) fractional operators. Hence, keeping in view the above-mentioned problems in physics in the current study, the generalized properties are derived M–L functions connected with R–L fractional operators that are investigated in the generalized form. These extended special operators will be used for the solutions of generalized kinetic energy equation. The M–L function is a fundamental special function with a wide range of applications in mathematics, physics, engineering, and various scientific disciplines. Ayub et al. gave the definition of newly extended M–L

(

p
,
s
,
k

)

\left(p,s,k)

function. Also, they gave its convergence condition and found several results relevant to that. The purpose of this study is to investigate newly extended M–L function and study its elementary properties and integral transforms such as Whittaker transform and fractional Fourier transform. The R–L fractional operator is a fundamental concept in fractional calculus, a branch of mathematics that generalizes differentiation and integration to non-integer orders. In this study, we discuss the relation of M–L

(

p
,
s
,
k

)

\left(p,s,k)

-function and R–L fractional operators. In some cases, fractional calculus is used to describe kinetic energy equations, particularly in systems where fractional derivatives are more appropriate than classical integer-order derivatives. The M–L function can appear as a solution or as a part of the solution to these fractional kinetic energy equations. Also, we gave the generalization of kinetic energy equation and its solution in terms of newly extended M–L function.
Magnetohydrodynamic water-based hybrid nanofluid flow comprising diamond and copper nanoparticles on a stretching sheet with slips constraints
Authors: Yasmin Humaira , AL-Essa Laila A. , Lone Showkat Ahmad , Alrabaiah Hussam , Raizah Zehba , Saeed Anwar
Published: April 2024

Hybrid nanofluid problems are used for augmentation of thermal transportation in various industrial applications. Therefore, the present problem is studied for the heat and mass transportation features of hybrid nanofluid caused by extending surface along with porous media. In this investigation, the authors have emphasized to analyze hybrid nanofluid flow containing diamond and copper nanoparticles on an extending surface. Furthermore, the velocity, temperature, and concentration slip constraints are adopted to examine the flow of fluid. Heat source, chemical reactivity, thermal radiation, Brownian motion and effects are taken into consideration. Nonlinear modeled equations are converted into dimensionless through similarity variables. By adopting the homotopy analysis method, the resulting equations are simulated analytically. The impacts of various emerging factors on the flow profiles (i.e., velocities, temperature, concentration, skin frictions, local Nusselt number, and Sherwood number) are shown using Figures and Tables. The major key findings reveal that the hybrid nanofluid temperature is higher but the concentration is lower for a Brownian diffusivity parameter. Moreover, increment role of heat transport is achieved due to the increment in radiation factor, thermophoresis, Brownian motion factors, and Eckert number. It has also been observed that velocity in x-direction converges in the region

−
0.8
≤

ℏ

f

≤
0.5

-0.8\le {\hslash }_{\text{f}}\le 0.5

, in y-direction velocity is convergent in the zone

−
0.6
≤

ℏ

g

≤
0.35

-0.6\le {\hslash }_{\text{g}}\le 0.35

, while temperature converges in the region

−
0.6
≤

ℏ

θ

≤
0.4

-0.6\le {\hslash }_{\text{θ}}\le 0.4

and concentration converges in the region

−
0.5
≤

ℏ

φ

≤
0.4

-0.5\le {\hslash }_{\text{φ}}\le 0.4

.
The use of augmented reality for renovation of cultural heritage sites
Authors: Sachenko Anatoliy O. , Kit Ivan R.
Published: April 2024

Augmented reality is an innovative technology that merges the virtual and real worlds to create a unique interactive experience for users. Although the technology only became widely known in the mid-2000s, its potential and applications continue to evolve rapidly, especially with the advent of smartphones and other mobile devices that allow a wide range of users to interact with augmented reality in their everyday lives. In the field of cultural heritage and tourism, augmented reality opens up new opportunities for the restoration and presentation of historical buildings and places that no longer exist or have been altered by time, giving visitors the opportunity to see and experience the historical environment in its original form. However, to effectively use augmented reality in this area, it is necessary to ensure an exact correspondence between virtual objects and the real environment, as well as to implement navigation functions that will help users easily navigate the virtually restored space. Developing and implementing augmented reality solutions requires not only technological expertise but also a deep understanding of the historical, cultural and social context of the objects being recreated. Based on our research, we have developed a concept of an augmented reality application for the reconstruction and promotion of cultural heritage. This includes methods for accurately recreating historical locations and objects in a virtual environment, as well as developing intuitive navigation tools for users. The main achievement of the work is the creation of a foundation for the further development of augmented reality technologies in this area, with a focus on improving the interaction between virtual and real components, which will help increase audience engagement and raise awareness of historical and cultural heritage. This opens up broad prospects for the use of augmented reality for cultural heritage, and the proposed approaches can serve as a basis for future innovative projects in this area.
Mode decomposed passivity-based speed control of DC drive with bidirectional Zeta-SEPIC DC-DC converter for light electric vehicles
Authors: Kuzyk Rostyslav-Ivan V. , Shchur Ihor Z.
Published: April 2024

Currently, light electric vehicles are rapidly developing in various kinds. To power these vehicles with batteries, the simplest electric drive system is a DC motor controlled by a DC-DC converter. This work utilizes a bidirectional Zeta-SEPIC DC-DC converter with an integrated DC motor. This implementation enables control of motor speed and torque in traction and regenerative braking modes. Additionally, it allows for the use of a lower voltage battery compared to the motor's rated voltage, reducing battery weight and increasing safety. In this work, a decomposition approach is applied. Two separate port-controlled Hamiltonian subsystems are obtained to adjust the motor angular velocity in the traction (Zeta) and braking (SEPIC) modes of the DC-DC converter. The Passivity-Based Control (PBC) method is used to synthesize the drive control subsystems in these modes. This method is based on the energy laws of processes in systems and provides asymptotic stability of nonlinear systems, in this case, two fourth-order subsystems for speed control. Two third-order current control subsystems synthesized by the PBC were used to limit the motor current at a given level. The synthesis resulted in sets of possible structures of control influence formers (CIFs) for all PBC subsystems using Zeta and SEPIC DC-DC converters. The study analyzed the operation of the obtained structures of the CIFs, selected the most effective ones, and determined the laws of adaptation of their parameters to the value of the motor angular velocity through computer simulation in Matlab/Simulink. The results of the simulation showed that the drive operated well in both static and dynamic modes.
Representation of Feminity in the 16th Century: The Main Character in Kei Ookubo's Anime Arte Series
Authors: Marselana Sela , Seruni Ayu Putri
Published: April 2024

Women in the renaissance era were portrayed as weak, emotional and illogical. This made it obligatory for women to be in the domestic sector, namely taking care of household affairs and limiting women to work. Until finally feminism was born in women who craved freedom. Today, feminism is present in various forms of literary works, one of which is the anime series Arte by Kei Ookubo. The purpose of this study is to analyze the basic character of feminism in the main character of the anime series Arte, Analyzing the internal and external factors of the emergence of the spirit of feminism. Both objectives are analyzed based on Sarah Gwyneth Ross's theory of feminism.This research uses a qualitative analysis description method with a literary feminism approach. This research uses a literature study where the object of research is the anime Arte which is researched using Sarah Gwyneth Ross's theory of feminism. It was found that Arte fulfills the five basic characters of feminism. First, Arte maintains she excellence in the arts. Second, Arte has intelligence equal to men. Third, the masculinity shown by Arte is the courage to speak up. Fourth, Arte understands the discrimination experienced by women so that she appreciates and praises women's hard work. Fifth, Arte has high creativity. Arte's inner voice to highlight she artistic talent is an internal factor in the formation of feminism. Meanwhile, the figure of father is an external factor in the formation of feminism.
RISING STARS: Androgens and immune cell function
Authors: Ainslie Rebecca J , Simitsidellis Ioannis , Kirkwood Phoebe M , Gibson Douglas A
Published: April 2024

Androgens can modulate immune cell function and may contribute to differences in the prevalence and severity of common inflammatory conditions. Although most immune cells are androgen targets, our understanding of how changes in androgen bioavailability can affect immune responses is incomplete. Androgens alter immune cell composition, phenotype, and activation by modulating the expression and secretion of inflammatory mediators or by altering the development and maturation of immune cell precursors. Androgens are generally associated with having suppressive effects on the immune system, but their impacts are cell and tissue context-dependent and can be highly nuanced even within immune cell subsets. In response to androgens, innate immune cells such as neutrophils, monocytes, and macrophages increase the production of the anti-inflammatory cytokine IL-10 and decrease nitric oxide production. Androgens promote the differentiation of T cell subsets and reduce the production of inflammatory mediators, such as IFNG, IL-4 and IL-5. Additionally, androgens/androgen receptor can promote the maturation of B cells. Thus, androgens can be considered as immunomodulatory agents, but further work is required to understand the precise molecular pathways that are regulated at the intersection between endocrine and inflammatory signals. This narrative review focusses on summarising our current understanding of how androgens can alter immune cell function and how this might affect inflammatory responses in health and disease.
Trimatės echokardiografijos vertė triburio vožtuvo funkcinio nesandarumo gydymo rezultatams prognozuoti
Authors:   , Bieliauskienė Gintarė
Published: April 2024

Usefulness of three-dimensional echocardiography to predict the treatment results in patients with functional tricuspid valve regurgitation
Onkohematologinių pacientų psichologinės savijautos kismas taikant agresyvų gydymą
Authors:   , Turlinskienė Marija
Published: April 2024

The Changes in Oncohematological Patients‘ Psychological Well-Being during Aggressive Treatment
Kant’s analysis of the soul: correlation with the body, and the problem of existence
Authors: KOZLOVSKYI Viktor
Published: April 2024

The article highlights the conceptual issues related to Kant’s analysis of the soul, a concept of utmost importance for the metaphysics and psychology of German academic philosophy (Schulphilosophie) of the Enlightenment was significantly dependent on the developed and systematically presented philosophical and scientific ideas and concepts of Christian Wolff. Kantian philosophy, its themes, and conceptual language were formed in the crucible of Wolfean discourse, and from the early 1770s in the struggle against it, which led to the emergence of a new, critical philosophy – transcendental idealism, in which the problem of the soul, consciousness, and self-awareness became fundamental. It is this issue that was thoroughly covered in the «Critique of Pure Reason» and other works that were published later, after the first Critique. The article draws attention to Kant’s Lectures, which, on the one hand, demonstrate his critical attitude towards the so-called Wolfians, their metaphysics, and psychology, and, on the other hand, the lecture materials illustrate Kant's new conceptual position, and, what is important, develop, supplement and clarify it. The sources of Kant’s lectures are highlighted, taking into account the fact that we have at our disposal lecture notes, the authors of which are either unknown or, if known, their authorship is still somewhat doubtful, since they are notes that different people have rewritten. The article analyses lecture notes on psychology, the authors of which are more or less well-known, and experts recognize these notes as quite valid. The conceptual content of these lectures allows us to look at Kant’s understanding of the problem of the soul in a somewhat broader context compared to the «Critique of Pure Reason», where this problem is analyzed in connection with the paralogisms of reason and the transcendental deduction of categories. In his lectures on psychology, Kant draws attention to the problem of the interaction of the soul with the human body, the «location of the soul», linking it not so much to the organs of the human body (for example, the head) as to the location of a person as a bodily being in the world makes all acts of consciousness, self-awareness, and sense perception possible. Kant emphasizes the basic importance of such a spatial location of a person for the soul, as something that belongs to a person with a certain integrity, and not a separate organ, to act properly, to perform its cognitive functions. The article analyses the problem of existence, which is important for critical philosophy, its various modalities, and predication, with a special emphasis on the problem of the existence of metaphysical objects - the soul, God, and the world as a whole.
The debates on war and democracy
Authors: KIRYUKHIN Denys
Published: April 2024

Since the 1970s, scholars have begun to pay special attention to the questions of whether democracy guarantees peace, whether freedom should be sacrificed in the name of security during war, how sustainable peace is possible, and what threats war poses to democracy. In the same period, influenced by the legacy of Immanuel Kant and David Hume, the democratic peace hypothesis began to be developed. This article discusses the theoretical debate concerning this hypothesis, as well as the question of whether the type of political regime affects the state's success in war. An examining of the theoretical debates has shown that the proponents of the democratic peace hypothesis have not been able to provide convincing evidence of a direct link between the type of political regime and the willingness to initiate war or maintain peace. At the same time, the debate disproves another common belief, that of the military weakness of democracies. The article notes that the prevalent theoretical approach to studying the issue of war and democracy is based on an eschatological idea of the future democratic world. In contrast to this view, Gunther Anders’ idea of an “apocalypse without a Kingdom” opens up a new perspective for understanding war and democracy, which is that the destruction that war brings is not followed by the construction of a new world. In this case, the main task is not to achieve democracy as a result of war, but to preserve democracy during war.
Pretended antinomy of historical experience: To the G.-G. Gadamer and F.R. Ankersmit interpretations of the historical experience concept
Authors: ZYMOVETS Roman
Published: April 2024

The article is devoted to the analysis of the phenomenon of historical experience in Gadamer's hermeneutics and Ankersmit's philosophical-historical concept. The interest of the philosophy of history in experience was actualized against the background of exhaustion of the heuristic potential of historical narrativism and constructivism, closely related to the so-called "linguistic turn". At first glance, Gadamer and Ankersmit are representing antinomic interpretations of historical experience: as mediated by the effects of involvement in a tradition or heritage and direct, extracontextual encounter with the past. However, the investigation proves that, despite the apparent antinomy of these approaches, the Gadamerian hermeneutic experience as an experience of the prevailing historical reality is not so far from the sublime historical experience of Ankersmit. And, on the contrary, the sublime historical experience, despite its claims to immediacy, turns out to be an experience of the finitude of human existence, that is, it is close to what Gadamer considered the essence of hermeneutic experience. In both cases, historical experience is considered as a condition for the possibility of understanding the past, and therefore, the question of the universal structure of such experience and understanding necessarily arises. The differences in the positions of the two authors stem from fundamentally different ontological prejudices that they share. For Gadamer, this is the reduction of history to a linguistically structured heritage, as a result of which most of the past falls out of hermeneutic experience. For Ankersmit, this is an uncritical understanding of time, as a result of which his concept of the sublime does not receive a reliable methodological foundation. Clarification of the temporality of the sublime historical, as well as rejection of the rigid connection between historical experience and language, open the prospect of removing the abstract antinomy of contextuality and immediacy of historical experience. The temporality of human existence turns out to be a universal prerequisite of historical experience, the two opposite forms of which are heredity and discontinuity. Contrary to the widespread criticism of Ankersmit's theory as far from historiographical practice, the development of the potential of the concept of sublime historical experience reveals its relevance to the dynamic and tragic modern history that Ukraine is currently experiencing.
Pediatric Physical Restraint Coding in US Hospitals: A 2019 Kids Inpatient Database Study
Authors: Luccarelli James , Kalluri Aditya S. , Kalluri Nikita S. , McCoy Thomas H.
Published: April 2024

BACKGROUND

Reduction of physical restraint utilization is a goal of high-quality hospital care, but there is little nationally-representative data about physical restraint utilization in hospitalized children in the United States. This study reports the rate of physical restraint coding among hospitalizations for patients aged 1 to 18 years old in the United States and explores associated demographic and diagnostic factors.

METHODS

The Kids’ Inpatient Database, an all-payors database of community hospital discharges in the United States, was queried for hospitalizations with a diagnosis of physical restraint status in 2019. Logistic regression using patient sociodemographic characteristics was used to characterize factors associated with physical restraint coding.

RESULTS

A coded diagnosis of physical restraint status was present for 8893 (95% confidence interval [CI]: 8227–9560) hospitalizations among individuals aged 1 to 18 years old, or 0.63% of hospitalizations. Diagnoses associated with physical restraint varied by age, with mental health diagnoses overall the most frequent in an adjusted model, male sex (adjusted odds ratio [aOR] 1.56; 95% CI: 1.47–1.65), Black race (aOR 1.43; 95% CI: 1.33–1.55), a primary mental health or substance diagnosis (aOR 7.13; 95% CI: 6.42–7.90), Medicare or Medicaid insurance (aOR 1.33; 95% CI: 1.24–1.43), and more severe illness (aOR 2.83; 95% CI: 2.73–2.94) were associated with higher odds of a hospitalization involving a physical restraint code.

CONCLUSIONS

Physical restraint coding varied by age, sex, race, region, and disease severity. These results highlight potential disparities in physical restraint utilization, which may have consequences for equity.
Creencias de Padres e Hijos Sobre el Asma: Implicancias Para la Adherencia al Tratamiento
Authors: Galdames Cruz Susan , Álvarez Cruz Lys , Barrios Avilés Macarena , Paredes Bravo Viviana , Rodríguez Maturana Verónica
Published: April 2024

Este trabajo describe y establece una relación entre creencias de niños con asma y las creencias de sus padres sobre asma y su tratamiento. Mediante un diseño correlacional transversal, con muestreo intencional, se evaluó a 40 niños entre 5 y 16 años con asma y a sus respectivos 40 adultos cuidadores. Se usó el cuestionario IPQ (Illness Perception Questionnaire), adaptado, para evaluar creencias de enfermedad. Los resultados muestran que existe correlación positiva baja-moderada, significativa, en tres de los seis tipos de creencias evaluadas: temporalidad, consecuencias y emocionalidad asociada al asma. Por otro lado, las creencias de los padres fueron más fuertes que las de los hijos en las creencias de identidad, consecuencias, emocionalidad y causalidad asociada al asma. La baja concordancia entre las respuestas de padres e hijos lleva a concluir la necesidad de educar de forma directa a los niños así como a sus padres con respecto al automanejo de su enfermedad. Se presentan algunas reflexiones sobre adherencia.
VIH y COVID-19: Una revisión narrativa rápida.
Authors: Farías Aguilera Alberto
Published: April 2024

Introducción: El impacto del SARS-CoV-2 en la pandemia del VIH, era desconocido en enero del 2020, pero transcurridos casi seis meses de la aparición del COVID-19, ya contamos con variadas publicaciones académicas de esta sindemia. El presente artículo es una revisión narrativa rápida de la literatura científica actual sobre VIH y COVID-19. Metodología: Se revisaron publicaciones en buscadores académicos a mediados de mayo del 2020 sobre VIH y COVID-19. Se encontraron editoriales y cartas al editor, correspondencia, viewpoint, artículos originales [algunos pre-print], notas de campo y comentarios. Todos con valiosa información clínica sobre la relación entre ambas epidemias. Desarrollo: Se clasificaron las publicaciones temáticamente en: respuesta clínica de personas VIH positivas afectadas por el COVID-19, farmacología, mantención y adaptación de los servicios de salud sexual, lecciones del VIH para la respuesta al COVID-19, poblaciones clave, efectos psicosociales, estigma y discriminación. Conclusiones: No hay evidencia de que personas VIH positivas, en TARV y por tanto, sin compromiso inmune, tengan mayor riesgo de COVID-19; tampoco en personas en etapa SIDA. Sí hay evidencia de mayor riesgo con edad avanzada y comorbilidades. No hay evidencia que sostenga que el TARV es efectivo para el SARS-CoV-2. Los servicios de salud sexual pueden y deben adaptarse a la contingencia. El VIH entrega importantes lecciones para la respuesta al COVID-19. Las poblaciones clave, requieren especial protección. Los efectos psicosociales y el estigma y la discriminación del COVID-19 y el VIH, generan impactos en la respuesta de la epidemia.
Parallel Implementation of the Algorithm for Correction of Antenna Rule Violations in OpenLane Design Flow
Authors: Bulakh Dmitriy Aleksandrovich , Korshunov Andray Vladimirovich
Published: April 2024

The open IC design flow OpenLane make available the RTL-to-GDS design flow to be implemented, but still some tasks remain unsolved. An example of such task is the correction of antenna rules violations. The detection tools for this procedure are the part of the OpenLane flow but it does not contain any tools for avoiding them. In this article the software is presented that has been developed and allows to avoid violations of antenna rules based on input data in the form of LEF file with information about the standard cell library and DEF file with information about the placement and routing of the design. A parallel implementation is also described; we show the results of more than 60% gain in time with using parallel version in comparison with sequential version. The article describes both the developed algorithm and the software built on its basis, the capability of embedding into an open OpenLane flow, and an example of embedding script code. The use of the developed software makes it possible to correct a significant part of antenna rules violations, thereby increasing the yield.
Application of Machine Learning Algorithms to Predict Turbulent Viscosity
Authors: Romanova Daria Igorevna , Epikhin Andrey Sergeevich , Ilina Daria Yurevna
Published: April 2024

The article discusses machine learning algorithms for predicting turbulent viscosity using the case of flow past the backward-facing step. The training data is obtained by calculations using the OpenFOAM software package and a turbulence model. The significance of flow parameters, including velocity fluctuations, pressure and velocity gradients, strain rate tensor and their combinations and invariants are analyzed for predicting turbulent viscosity. Different machine learning algorithms are compared. It is found that the most optimal algorithm for predicting turbulent viscosity in this case is the Decision Tree Regressor. Using the chosen model, the distribution of turbulent viscosity in the computational domain is predicted for various Reynolds numbers.
Studying the Structure of the Sound of Russian Speech by Chinese and Ghanaian Students in a Digital Format: a Linguodidactic Aspect
Authors: Deryabina Svetlana Aleksandrovna , Ren Wanying , Nketiah Eugenia
Published: April 2024

The purpose of the research is to study the peculiarities of the structure of the sound of Russian speech by Chinese and Ghanaian students at different levels of study, based on experimental phonetic programs. The subject of the study is the intonational structure of the main communicative intentions: greeting, address, completion, incompletion, a question without an interrogative word, a question with the Russian conjunction «а» (“and”), a positive evaluation and surprise. The study contributes to the creation of an ethno-oriented methodology for teaching Russian intonation. The scientific novelty is in the analysis of the sound of the Russian speech of foreign students at the syntagma level in comparison with that of a native Russian speaker using the Praat and Lingvodoc programs. The results of the study consist in the visual representation of the peculiarities of the structure of the main communicative intentions in the Russian speech of Chinese and Ghanaians to predict and correct errors at the level of intonation.
The Use of Digital Methods to Identify the Structural and Territorial Units of the Central-Southern Dialect of the Udmurt Language Based on the Analysis of Field Records
Authors: Utkina Alexandra Filippovna
Published: April 2024

The article presents the results of computer phonetic-etymological and glottochronological analysis of data from the dialect of the village of Bobya-Ucha, Malopurginsky District, Udmurt Republic. As far as we know, the dialectal peculiarities of the studied material have not previously attracted the attention of researchers. In the course of work under the RSF grant, audio recordings of two dictionaries of the colloquial language were collected. The vocabulary of which is still used in everyday life. At the present days, the audio materials of the dictionaries were transcribed and placed on the LingvoDoc platform (lingvodoc.ispras.ru), which made it possible to establish etymological links with the basic dictionaries of Udmurt dialects. Then, with the help of special programs, the divergence of the Bobya-Ucha dialect from the Udmurt literary language was analyzed. The phonetic peculiarities of the studied dialect were revealed and its dialectal affiliation was clarified. The comparative-historical analysis of phonetic peculiarities has shown that the consonant phonemes of the studied dialect have not undergone any changes and have no dialectal peculiarities. However, there is a specific sound ’ in the Bobya-Ucha dialect, the study of which requires further research. The vocalic system of the studied vernacular is determined by several changes in the acoustic and articulatory properties of individual phonemes: *ɪ̈ > ə, *ɐ > ə, *ɞ > ɜ. Thus, based on the etymological-phonetic and glottochronological analysis (96% coincidence), we can see that the dialect of the village Bobya-Ucha belongs to the central-southern dialect of the Udmurt language.