bluuebunny/crossref_metadata_2025 huggingface dataset:
Social Media and the Transformation of the Physician-Patient Relationship: Viewpoint
Authors: Forgie Ella M E , Lai Hollis , Cao Bo , Stroulia Eleni , Greenshaw Andrew J , Goez Helly
Published: October 2021

As many as 80% of internet users seek health information online. The social determinants of health (SDoH) are intimately related to who has access to the internet and health care as a whole. Those who face more barriers to care are more likely to benefit from accessing health information online, assuming the information they are retrieving is accurate. Virtual communities on social media platforms are beginning to serve as venues for seeking health information online because peers have been shown to influence health behavior more than almost anything else. As a positive mediator of health, social media can be used as a direct or indirect mode of communication between physicians and patients, a venue for health promotion and health information, and a community support network. However, false or misleading content, social contagion, confirmation bias, and security and privacy concerns must be mitigated to realize the full potential of social media as a positive mediator of health. This paper presents the shifting dynamics of how such communities are affecting physician-patient relationships. With the intersections between the SDoH, social media, and health evolving, physicians must take into consideration these factors when establishing their relationships with patients. We argue a paradigm shift in the physician-patient relationship is warranted, one where physicians acknowledge the impacts of the SDoH on information-seeking behavior, recognize the positive and negative roles of social media as a mediator of health through the lens of the SDoH, and use social media to catalyze positive changes in the physician-patient relationship. We discuss how the physician-patient relationship must evolve to accommodate for the ever-increasing role of social media in health and to best use social media as a tool to improve health outcomes. Finally, we present a fluid and multicomponent diagram that we believe will assist in framing future research in this area. We conclude that it is ineffective and even counterproductive for physicians to ignore the relationship between social media, the SDoH and health, their impact on one another, and the effect it has on designing the medical encounter and the delivery of care under the definition of precision medicine.
Technology Support Challenges and Recommendations for Adapting an Evidence-Based Exercise Program for Remote Delivery to Older Adults: Exploratory Mixed Methods Study
Authors: Gell Nancy , Hoffman Elise , Patel Kushang
Published: October 2021

Background

Tele-exercise has emerged as a means for older adults to participate in group exercise during the COVID-19 pandemic. However, little is known about the technology support needs of older adults for accessing tele-exercise.

Objective

This study aims to examine the needs of older adults for transition to tele-exercise, identify barriers to and facilitators of tele-exercise uptake and continued participation, and describe technology support challenges and successes encountered by older adults starting tele-exercise.

Methods

We used an exploratory, sequential mixed methods study design. Participants were older adults with symptomatic knee osteoarthritis (N=44) who started participating in a remotely delivered program called Enhance Fitness. Before the start of the classes, a subsample of the participants (n=10) completed semistructured phone interviews about their technology support needs and the barriers to and facilitators for technology adoption. All of the participants completed the surveys including the Senior Technology Acceptance Model scale and a technology needs assessment. The study team recorded the technology challenges encountered and the attendance rates for 48 sessions delivered over 16 weeks.

Results

Four themes emerged from the interviews: participants desire features in a tele-exercise program that foster accountability, direct access to helpful people who can troubleshoot and provide guidance with technology is important, opportunities to participate in high-value activities motivate willingness to persevere through the technology concerns, and belief in the ability to learn new things supersedes technology-related frustration. Among the participants in the tele-exercise classes (mean age 74, SD 6.3 years; 38/44, 86% female; mean 2.5, SD 0.9 chronic conditions), 71% (31/44) had a computer with a webcam, but 41% (18/44) had little or no experience with videoconferencing. The initial technology orientation sessions lasted on average 19.3 (SD 10.3) minutes, and 24% (11/44) required a follow-up assistance call. During the first 2 weeks of tele-exercise, 47% of participants (21/44) required technical assistance, which decreased to 12% (5/44) during weeks 3 to 16. The median attendance was 100% for the first 6 sessions and 93% for the subsequent 42 sessions.

Conclusions

With appropriate support, older adults can successfully participate in tele-exercise. Recommendations include individualized technology orientation sessions, experiential learning, and availability of standby technical assistance, particularly during the first 2 weeks of classes. Continued development of best practices in this area may allow previously hard-to-reach populations of older adults to participate in health-enhancing, evidence-based exercise programs.
Using Venn Diagrams to Evaluate Digital Contact Tracing: Panel Survey Analysis
Authors: Daniore Paola , Nittas Vasileios , Moser André , Höglinger Marc , von Wyl Viktor
Published: October 2021

Background

Mitigation of the spread of infection relies on targeted approaches aimed at preventing nonhousehold interactions. Contact tracing in the form of digital proximity tracing apps has been widely adopted in multiple countries due to its perceived added benefits of tracing speed and breadth in comparison to traditional manual contact tracing. Assessments of user responses to exposure notifications through a guided approach can provide insights into the effect of digital proximity tracing app use on managing the spread of SARS-CoV-2.

Objective

The aim of this study was to demonstrate the use of Venn diagrams to investigate the contributions of digital proximity tracing app exposure notifications and subsequent mitigative actions in curbing the spread of SARS-CoV-2 in Switzerland.

Methods

We assessed data from 4 survey waves (December 2020 to March 2021) from a nationwide panel study (COVID-19 Social Monitor) of Swiss residents who were (1) nonusers of the SwissCovid app, (2) users of the SwissCovid app, or (3) users of the SwissCovid app who received exposure notifications. A Venn diagram approach was applied to describe the overlap or nonoverlap of these subpopulations and to assess digital proximity tracing app use and its associated key performance indicators, including actions taken to prevent SARS-CoV-2 transmission.

Results

We included 12,525 assessments from 2403 participants, of whom 50.9% (1222/2403) reported not using the SwissCovid digital proximity tracing app, 49.1% (1181/2403) reported using the SwissCovid digital proximity tracing app and 2.5% (29/1181) of the digital proximity tracing app users reported having received an exposure notification. Most digital proximity tracing app users (75.9%, 22/29) revealed taking at least one recommended action after receiving an exposure notification, such as seeking SARS-CoV-2 testing (17/29, 58.6%) or calling a federal information hotline (7/29, 24.1%). An assessment of key indicators of mitigative actions through a Venn diagram approach reveals that 30% of digital proximity tracing app users (95% CI 11.9%-54.3%) also tested positive for SARS-CoV-2 after having received exposure notifications, which is more than 3 times that of digital proximity tracing app users who did not receive exposure notifications (8%, 95% CI 5%-11.9%).

Conclusions

Responses in the form of mitigative actions taken by 3 out of 4 individuals who received exposure notifications reveal a possible contribution of digital proximity tracing apps in mitigating the spread of SARS-CoV-2. The application of a Venn diagram approach demonstrates its value as a foundation for researchers and health authorities to assess population-level digital proximity tracing app effectiveness by providing an intuitive approach for calculating key performance indicators.
The Pandemic, Infodemic, and People’s Resilience in India: Viewpoint
Authors: Syed Abdul Shabbir , Ramaswamy Meghna , Fernandez-Luque Luis , John Oommen , Pitti Thejkiran , Parashar Babita
Published: October 2021

The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused widespread fear and stress. The pandemic has affected everyone, everywhere, and created systemic inequities, leaving no one behind. In India alone, more than 34,094,373 confirmed COVID-19 cases and 452,454 related deaths have been reported as of October 19, 2021. Around May 2021, the daily number of new COVID-19 cases crossed the 400,000 mark, seriously hampering the health care system. Despite the devastating situation, the public response was seen through their efforts to come forward with innovative ideas for potential ways to combat the pandemic, for instance, dealing with the shortage of oxygen cylinders and hospital bed availability. With increasing COVID-19 vaccination rates since September 2021, along with the diminishing number of daily new cases, the country is conducting preventive and preparatory measures for the third wave. In this article, we propose the pivotal role of public participation and digital solutions to re-establish our society and describe how Sustainable Development Goals (SDGs) can support eHealth initiatives and mitigate infodemics to tackle a postpandemic situation. This viewpoint reflects that the COVID-19 pandemic has featured a need to bring together research findings across disciplines, build greater coherence within the field, and be a driving force for multi-sectoral, cross-disciplinary collaboration. The article also highlights the various needs to develop digital solutions that can be applied to pandemic situations and be reprocessed to focus on other SDGs. Promoting the use of digital health care solutions to implement preventive measures can be enhanced by public empowerment and engagement. Wearable technologies can be efficiently used for remote monitoring or home-based care for patients with chronic conditions. Furthermore, the development and implementation of informational tools can aid the improvement of well-being and dissolve panic-ridden behaviors contributing toward infodemics. Thus, a call to action for an observatory of digital health initiatives on COVID-19 is required to share the main conclusions and lessons learned in terms of resilience, crisis mitigation, and preparedness.
Correction: Use of Deep Learning to Predict Acute Kidney Injury After Intravenous Contrast Media Administration: Prediction Model Development Study (Preprint)
Authors: Yun Donghwan , Cho Semin , Kim Yong Chul , Kim Dong Ki , Oh Kook-Hwan , Joo Kwon Wook , Kim Yon Su , Han Seung Seok
Published: October 2021

INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID)

RR2-10.2196/27177

INTERNATIONAL REGISTERED REPORT

RR2-10.2196/27177
Research Using Social Media to Recruit Research Participants Should Proceed With Caution. Comment on “Telemanagement of Home-Isolated COVID-19 Patients Using Oxygen Therapy With Noninvasive Positive Pressure Ventilation and Physical Therapy Techniques: Randomized Clinical Trial” (Preprint)
Authors: Chen Chih-Wei , Wei James Cheng-Chung
Published: October 2021

UNSTRUCTURED

The original article provided a deeper understanding on the effectiveness of home-based oxygen therapy with bilevel positive airway pressure and that of osteopathic manipulative respiratory and physical therapy techniques in impeding exacerbation of early-stage COVID-19 pneumonia. In this letter, we propose further issues that should be discussed in terms of research design, technologies for patient recruitment, and the influence of the telemanagement system on health care development.
L’écriture et la vie selon Anne-Lise Grobéty
Authors: Cossy Valérie
Published: October 2021

Dix ans après la disparition de l’écrivaine, cet article s’efforce de cerner ce qui rend mémorable l’écriture d’Anne-Lise Grobéty. Sans prétendre à l’analyse rigoureuse, il invite à saisir les ressources de l’union qu’elle a tissée de sa plume entre la légèreté et la gravité.

Keywords : Anne-Lise Grobéty, écriture, langue, humour, sens, auteur, lecteur, Henri Roorda.
Sovrapposizioni. Testo, immagine e fotografia ne "Il Giuoco dell’Oca" di Edoardo Sanguineti
Authors: Hufnagel Henning
Published: October 2021

Il saggio legge il romanzo di Sanguineti Il Giuoco dell’Oca attraverso un nuovo focus: la medialità. Vi si dimostra come, anche senza includere alcuna immagine materiale, esso funzioni come fototesto, anzi costituisca un fototesto di livello potenziato: articolandosi in una serie ecfrastica, mettendo in scena tensioni riflessive tra lingua e immagine, simulando persino il modo di percezione dell’obiettivo fotografico. Attraverso le immagini, Sanguineti contesta non solo i modi narrativi convenzionali, ma spinge la sua sperimentazione anche oltre le avanguardie francesi con le quali dialoga, da Breton ai contemporanei Robbe-Grillet e Sollers.

Keywords: narratività, intermedialità, fotografia, Nouveau roman, Tel Quel.
"Harri eta herri/Piedra y pueblo" de Gabriel Aresti. Un abecedario vital
Authors: Kortazar Jon
Published: October 2021

Tras la aparición de Harri eta Herri/Piedra y pueblo nada fue igual en la historia de la poesía vasca. Gabriel Aresti abrió un camino poético eficaz para la expresión de una sociedad que boqueaba bajo el franquismo con un riesgo serio de pérdida de la lengua, con una situación social sangrante y con abismales diferencias sociales, con la presencia en el ámbito internacional de nuevas formas de hacer política, entre las que destacó simbólicamente la Revolución Cubana, y que ya anunciaba la presencia de ETA. Por sus referencias culturales, que reunían a todo el arco creativo en el País Vasco, por su interés en retomar la tradición para darle nuevo aliento, por su concepto de poesía fácil e inteligible, por su compromiso social, Gabriel Aresti representó a través de su poesía una sociedad que sufría y luchaba, y sobre todo que vivía con dignidad.

Keywords: Aresti, Harri eta Herri, País Vasco, poesía vasca.
La ética como estética del presente (De la formación ideológica de Miguel Hernández)
Authors: Urrutia Jorge
Published: October 2021

El artículo desea mostrar la evolución estética de Miguel Hernández desde la figura del poeta-pastor de sus inicios hasta el poeta neopopular del Cancionero y Romancero de ausencias, a través de su trayectoria ideológica. Se resalta la importancia de un poema habitualmente considerado menor, para su autodescubrimiento como poeta proletario y la fijación de una poética ética.

Keywords: Miguel Hernández, neopopularismo, poesía proletaria, poética.
Iconicidad y autorreflexión implícita en la poesía de Miguel Hernández
Authors: López Guil Itzíar
Published: October 2021

Este trabajo se propone demostrar la existencia en la poesía de Miguel Hernández de diversos procedimientos autorreferenciales de carácter icónico con los que crea en sus poemas un segundo nivel de sentido de carácter implícito y metaliterario. Se trata de estrategias que conoce y descubre al lado de Sijé, cuando forma parte de El Gallo Crisis, y que, incluso tras trabar amistad con Neruda y cambiar de poética, seguirá explorando y poniendo en práctica hasta el prematuro e injusto final de su vida.

Keywords: Autorreferencialidad, iconicidad, Miguel Hernández, «Un carnívoro cuchillo», «Umbrío por la pena», «Como el toro he nacido para el luto», «Para la libertad», «Llegó con tres heridas».
Autobiografía, autorretrato y autorreferencia en el "Cancionero" de Miguel Hernández
Authors: Rovira José Carlos
Published: October 2021

Desde los conceptos de autobiografía, autorretrato y autorreferencia se realiza la lectura de algunos poemas del Cancionero y romancero de ausencias, no tanto como una perspectiva surgida desde el campo de la teoría literaria, sino insistiendo en los valores que, en la última obra de Miguel Hernández, se entremezclan como dimensión de una existencia en la que sobrevivir era construir una escritura que daba cuenta de sí mismo. Reflejaba así su imagen e incidía metafóricamente en lo que estaban viviendo, como reflejo social y colectivo, aquellos que sufrían las mismas consecuencias de la represión, las cárceles y las condenas a muerte. La realidad provocaba la afirmación de sí mismo a través de recursos que, junto a retóricos, podían testimoniar una nueva dimensión de una poesía y una historia que podemos considerar como la de la derrota en la España de la postguerra civil.

Keywords: Autobiografía, autorretrato, autorreferencia, historia, sociedad.
Penilaian Risiko Kualitatif Masuknya Rabies Melalui Pergerakan Anjing dari Provinsi Jawa Barat ke Kota Surakarta
Authors: Permatasari Indri , Sumiarto Bambang , Susetya Heru
Published: October 2021

Abstrak      Lalu lintas anjing dari daerah tertular rabies ke daerah bebas rabies masih terjadi di Indonesia. Hal ini menjadi salah satu pemicu terhadap munculnya kasus rabies di daerah bebas. Penelitian ini bertujuan untuk melakukan penilaian risiko kualitatif kemungkinan masuknya rabies melalui pergerakan anjing konsumsi dari Jawa Barat ke Kota Surakarta, Provinsi Jawa Tengah. Metode pengumpulan data yang digunakan dalam penelitian ini menggunakan data primer dan data sekunder. Data primer diperoleh dari wawancara, kuesioner, pendapat pakar, dan observasi langsung di lapangan. Data sekunder diperoleh melalui kajian literatur, penelusuran publikasi ilmiah, dan dokumen dari instansi berwenang yang tidak dipublikasikan. Hasil penelitian menunjukkan bahwa penilaian pelepasan dari daerah asal anjing adalah “sedang” dengan ketidakpastian rendah. Tingkat kejadian rabies pada hewan di Provinsi Jawa Barat tahun 2019 sebesar 3,1%. Penilaian pendedahan adalah “tinggi” dengan ketidakpastian rendah karena frekuensi pengiriman anjing konsumsi dari Jawa Barat dilakukan setiap hari. Penilaian dampak adalah “tinggi” dengan ketidakpastian rendah karena ada dampak tunggal yang masuk dalam kategori signifikan di tingkat nasional. Hasil penelitian dapat disimpulkan bahwa penilaian risiko kualitatif masuknya rabies ke Kota Surakarta adalah tinggi dengan ketidakpastian rendah. Evaluasi kemungkinan kualitatif dapat mempertimbangkan tingkat kejadian rabies daerah asal dan frekuensi pengiriman anjing konsumsi setiap hari yang merupakan masalah penting risiko masuknya rabies.
Efficacy of Albendazole Against Strongylus sp. and Hematology Changes on Equine in Yogyakarta Special Region
Authors: Yuriadi Yuriadi , Tjahajati Ida , Mulyani Guntari Titik , Muqit Kelviano , Rahmanita Aidah
Published: October 2021

The infestation of Strongylus sp. in horses can cause losses to horse breeders, including anorexia, anemia, gastrointestinal diseases and can cause death and decrease the horse population in DIY. Albendazole was a Benzimidazole preparation that is often used to treat worms in ruminants. This study also aims to determine the effect of Albendazole on blood images before and after treatment. The material used in this study were 10 horses with male and female sex,  over 3 years old, and infected with Strongylus sp. with an infestation rate of 200 EPG in faeces. Before treatment of drug was carried out, the faeces was examined with Mc Master method. After treatment with Albendazole, the worm eggs were examined three times at intervals of three days. Routine examination of worm eggs and blood was carried out at the Laboratory of the Department of Internal Medicine, Faculty of Veterinary Medicine, Universitas Gadjah Mada. The results showed that the EPG number decreased from the 0th, 3rd, 6th and 9th day of examinations. The average number of EPG on the 0th day was 990 eggs/gram, and the examination on the 9th day showed the number of eggs was 0 eggs/gram. The results of the hematology examination also showed no significant difference except for the high number of eosinophils on the 12th day after drug administration. The conclusion from this research is that Albendazole as a worm medicine can kill Srongylus sp. however, it does not affect the horse's hematology and health status.
Biofilm Formation and its Association with Antibiotic Susceptibility Pattern in Methicillin-resistant Staphylococcus aureus isolates
Authors: Chaudhary Bajarangi Lal , Bisht Dakshina , Faujdar Sameer Singh
Published: October 2021

Methicillin-resistant Staphylococcus aureus is a clinically significant pathogen that causes infections ranging from skin and soft tissue infections to life-threatening sepsis. Biofilm formation by MRSA is one of the crucial virulence factor. Determination of beta-lactamase and biofilm production among Staphylococcus aureus was obtained from various clinical specimens. Standard bacteriological procedures were used for isolation and identification and antibiotic sensitivity was determined using the Kirby Bauer disc diffusion method according to CLSI guidelines. The cloverleaf method, acidometric, iodometric and chromogenic methods were used to detect beta-lactamase while the microtiter plate method and Congo red agar method were used to detect biofilm production. Of the 288 MRSA strains isolated from various clinical specimens,198 (67.07%) were biofilm producers. Cloverleaf and chromogenic (nitrocefin) disc shows 100% results for beta-lactamase detection. Vancomycin was 100% sensitive followed by teicoplanin (92.36%) and linezolid (89.93%). Cloverleaf and nitrocefin disc methods were the most sensitive for detection of beta-lactamase in S. aureus and there was no significant relation between biofilm production and antibiotic sensitivity pattern of S. aureus.
An Investigation Profile in Pediatric Patients Suspected of Acute Hepatitis A
Authors: Rana Geetika , Lone Owias Yousf
Published: October 2021

Hepatitis A virus (HAV) infection is one of the important causes of hepatitis in developing countries. It is transmitted through feco-oral route. This poses major health problems in children. Serum samples of the patients from pediatrics department suspected of acute viral hepatitis presenting with clinical features like fever, nausea, vomiting, and jaundice were collected and analyzed by using commercially available mini VIDAS 307 (Biomeriux) to detect anti HAV IgM antibodies. A nine months prospective study was conducted in the Department of Microbiology and immunology of Shri Guru Ram Rai Institute of Medical and health science Dehradun, India. Of the 47 serum samples received during the study period, 23 (48.93%) were found to be positive for anti-HAV IgM (VIDAS 307 Biomeriux). The prevalence was found to be more in male patients than in female patients, that is,14 (60.8%) and 9 (39.13%) respectively, and was predominantly seen in the 5–10 years of the age group (60%). Peak cases were found in the month of October and November. The study showed a high positivity (48.93%) of HAV in this sub-Himalayan region indicating the role of preventive measures including safe drinking water, improved sanitation and vaccination in preventing infection. Thus, detection of anti-HAV IgM becomes the cornerstone entity for diagnosis.
Relationship between Radiological Findings with Bacterial Etiology of Community Acquired Pneumonia in Pediatric Population
Authors: Pandey Nidhi , Mittal Garima , Agarwal Nitika , Kakati Barnali , Agarwal R.K.
Published: October 2021

Pneumonia continues to be a major cause of morbidity and mortality in children. Pneumonia is the leading killer of children worldwide. For the diagnosis of pneumonia, the World Health Organization has introduced guidelines for the management of cases to reduce the mortality of these diseases on the basis of simple clinical signs followed by the empirical treatment with antibiotics. More than 99% of deaths related to pneumonia among children occur in countries having a low and middle income. To study the Radiological finding of Community-Acquired Pneumonia (CAP) in children. Across sectional study was conducted in which the sample size for the study was calculated from the expected prevalence of CAP based on other studies (74%). The sample size calculated by the required criterion for this study is 96. I was able to cover 118 patients as per the inclusion criteria in this study. The Patients of pediatric age groups and either sex attending tertiary care hospital with complaints suggestive of CAP. In this study total number of patients are 118 included who presented with the signs and symptoms suggestive of pneumonia. The findings of chest X-Ray of Right Lung with respect to different bacterial agents. Consolidation of the Right upper lobe is found to be statistically significant with respect to Streptococcus pneumonia and consolidation of the right lower lobe is found to be statistically significant with respect to bacteria Staphylococcus aureus whereas there is no statistically significant association with respect to other bacteria. The radiological finding of CAP in children attending pediatric OPD was observed that there was no association with any other bacteria.
Hero of the Soviet Union A. V. Sidorov, a military topographer
Authors: Dolgov E.I. , Sergeev S.V. , Nikonov A.V.
Published: October 2021

Military topographers made a significant contribution to achieving the Victory of the Soviet people in the Great Patriotic War of 1941–1945. For their professionalism, bravery and courage, many of them were submitted to government awards, orders and medals. At war a topographer performs an important and responsible, though not as heroic and risky job as, for example, a pilot or a tanker. Therefore, until recently, it was believed that there were no military topographers among the servicemen honoured with the highest distinction, the title of the Hero of the Soviet Union. However, by now, when the archive documents of the Russian Federation Defense Ministry have been fully opened, it is possible to observe the way of our colleague, Alexander Vasilyevich Sidorov, who was assigned the title of the Hero of the Soviet Union in 1943. A. V. Sidorov started his career in 1930 as a civilian topographer of the Central Asian Geodetic Administration (Tashkent). Since 1932, in the Military Topographic Service of the Red Army
Cervical Spine Epidural Abscess Caused by Brucellosis: A Case Report and Literature Review
Authors: Shafizad Misagh , Ehteshami Saeid , Shojaei Hamidreza , Khoshnoud Reza Jalili
Published: October 2021

We report a rare case of cervical epidural abscess at the C5-C6 levels.
The patient underwent surgery with complete abscess removal through C6
vertebral body corpectomy. The result of bacteriological culture was
Brucella melitensis. Brucellosis must be considered as a possible cause
of epidural abscess in patients from endemic area.
The relativistic feature of Hydrogen-like atoms in the Heisenberg picture
Authors: Jahanpanah J , Vahedi A , Khosrojerdi H .
Published: October 2021

The relativistic properties of Hydrogen-like atoms (HLAs) are here
investigated in the Heisenberg picture for the first time. The
relativistic vibrational Hamiltonian (RVH) is first defined as a power
series of harmonic oscillator Hamiltonian by using the relativistic
energy eigenvalue . By applying the first-order RVH (proportional to )
to the Heisenberg equation, a pair of coupled equations is turned out
for the relativistic motion of the electron’s position and linear
momentum. A simple comparison of the first-order relativistic and
nonrelativistic equations reveals this reality that the natural
(fundamental) frequency of HLA (like entropy) is slowly raised by
increasing the atomic number from . The second-order RVH (proportional
to ) has then been implemented to determine an exact expression for the
electron relativistic frequency in the different atomic energy levels.
In general, the physical role of RVH is fundamental because it not only
specifies the temporal relativistic variations of position, velocity,
and linear momentum of the oscillating electron, but also identifies the
corresponding relativistic potential, kinetic, and mechanical energies.
The results will finally be testified by demonstrating energy
conservation.
Haplotype-level metabarcoding of freshwater macroinvertebrate species: a prospective tool for population genetic analysis
Authors: Serrana Joeselle , Watanabe Kozo
Published: October 2021

The development and evaluation of DNA metabarcoding protocols for
haplotype-level resolution require attention, specifically for
population genetic analysis, i.e., parallel estimation of genetic
diversity and dispersal patterns among multiple species present in a
bulk sample. Further exploration and assessment of the laboratory and
bioinformatics strategies are warranted to unlock the potential of
metabarcoding-inferred population genetic analysis. Here, we assessed
the inference of freshwater macroinvertebrate haplotypes from DNA
metabarcoding data using mock samples with known Sanger-sequenced
haplotypes. We also examined the influence of different DNA template
concentrations and PCR cycles on detecting true haplotypes and the
reduction of spurious haplotypes obtained from DNA metabarcoding. We
tested our haplotyping strategy on a mock sample containing 20 specimens
from four species with known haplotypes based on the 658-bp Folmer
region of the mitochondrial cytochrome c oxidase gene. The read
processing and denoising step resulted in 14 zero-radius operational
taxonomic units (ZOTUs) of 421-bp length, with 12 ZOTUs having 100%
match with 12 of the Sanger haplotype sequences. Quality passing reads
relatively increased with increasing PCR cycles, and the relative
abundance of each ZOTUs was consistent for each cycle number. This
suggests that increasing the cycle number from 24 to 64 did not affect
the relative abundance of quality passing filter reads of each ZOTUs.
Our study demonstrated the ability of DNA metabarcoding to infer
intraspecific variability while highlighting the challenges that need to
be addressed before its possible applications to population genetic
studies.
Towards Protein Functions Prediction: An Inclusive Literature Review of Artificial Intelligent Techniques and Future Research Guidelines
Authors: ALSANOUSI WAFA ALAMEEN , AHMED NOSIBA YOUSIF , HAMID EMAN MOHAMMED , ELBASHIR K. MURTADA , WANG JIANXIN , KHAN NOMAN , AFNAN *
Published: October 2021

Proteins perform critical functions, and their role is closely
associated with their composition. Reliable prediction of protein
function using computational techniques is becoming necessary because
experimental limitations make it difficult to cover the massive rate of
discovered proteins and their genetic transformation. This paper surveys
the protein functions prediction, briefly discusses the employed
literature’s workflow and determines if the machine and deep learning
techniques have been widely used for similar objectives. Furthermore,
the paper discusses the trends of protein datasets and their features
and summarises researchers’ questions using these datasets. Many
features have been identified and extracted, ranging from traditional
physicochemical of amino acids and techniques for selecting features and
reducing the dimensionality. Distinct from previous study manuscripts,
we keep a detailed review of performance evaluation metrics and compare
employed protein function prediction methods, thereby concluding the
need for efficient, effective, and adaptable protein function prediction
methods in real-world scenarios. We describe the machine learning
processes and their development from elementary algorithms, such as
logistic regression, to more sophisticated methods like conventional and
highly developed sequential deep neural networks. The techniques of
computing the hyper-parameters that are adopted to improve prediction
efficiency have been discussed. Many studies reviewed implemented
machine and deep learning approaches for protein function prediction
compared with other methods. The critical challenge well noted in
protein function prediction is getting relevant information. Then,
approaches evaluated and provided future study prospects based on the
results drawn from previous studies. This review provides important
information as well as future prospects.
¿Por qué usar Whatsapp? responden egresados universitarios en México, una propuesta de comunicación personal masiva
Authors: Bordas-Beltrán José Luis , De Guadalupe Arras-Vota Ana María , Porras Flores Damián Aarón , Gutiérrez-Diez María del Carmen
Published: October 2021

La forma en el cual el proceso de comunicación se realiza ha ido evolucionando con el paso del tiempo, al igual que nuestra capacidad para adaptarnos a ello y utilizarlo como una herramienta más de nuestra forma natural de relacionarnos día con día. Por lo tanto, el presente estudio busca analizar la forma en que las personas en México valoran el uso del WhatsApp, por edad y género, así como el tiempo y los motivos que los llevan a utilizar la aplicación de mensajería instantánea (MI). La investigación es aplicada, de campo y descriptiva, utiliza los métodos: analítico sintético y teórico deductivo. Las técnicas de investigación utilizadas fueron bibliográficas, encuestas y entrevista estructurada, aplicada a una muestra de 237 usuarios de WA en México. Además, los resultados se analizaron con los paquetes SPSS y ATLAS. El análisis e interpretación de la información permite identificar que lo más valorado de WA, por las personas en México, es su función como medio de comunicación, la rapidez, y facilidad de uso y lo menos valorado es la información basura, la distracción y lo que aducen como robo de tiempo. Además, mientras más jóvenes son las personas es mayor el tiempo que dedican al uso de WA. Adicionalmente, el estudio presenta un modelo axiológico y teleológico sobre la percepción que tienen los usuarios sobre el WA, así como un modelo de Comunicación Personal Masiva. Comprender que el WA es valorado como medio de comunicación personal masiva rápida y fácil de utilizar permite que tanto grupos, empresas y organizaciones, de diversos giros, entre ellos de aplicaciones MI, lo puedan utilizar como canal de información para establecer contacto y enviar mensajes que generen relaciones interpersonales directas con aquellos a los que se pretende alcanzar.
Synthesis System Оf Algebra Algorithms Formulas
Authors:   Lviv Polytechnic National University, Vasyluk Andrii , Basyuk Taras ,   Lviv Polytechnic National University
Published: October 2021

In the article the authors have developed a mathematical support for the process of generating subject unitherms of formulas of algebra of algorithms. The analysis of features of construction of formulas of algebra of algorithms as a result of which it was found out, that today, subsystems with realization of processes of generation of subject unitherms on the basis of abstract unitherms with the subsequent adaptation of formulas are not realized in known systems that served as stimulus to intellectual analysis formulas of algebra of algorithms. It is described that the synthesis of algebra formulas of algorithms, and especially the generation of subject unitherms on the basis of abstract ones is an extremely complex and laborious process. Since all elements of the formula are interconnected, all changes in the algorithm’s formula affect its structure. Therefore, this is the main reason for the complexity of the described processes. One aspect of the synthesis of the formulas of the algebra of algorithms is the process of generating subject unitherms based on abstract unitherms. The signs of operations of the algebra of algorithms are briefly described. Mathematical support of the process of synthesis of algorithm algebra formulas is developed, which takes into account vertical and horizontal orientation and type of algorithm algebra formula: text unitherm, sequencing operation, elimination operation, parallel operation and corresponding cyclic sequencing operations, elimination and parallelization, as well as geometric parameters. The process of generating subject unitherms on the basis of abstract ones is previously described. The list of necessary eliminations and sequences for the synthesis of the corresponding formulas is determined. According to the properties of the signs of operations of the algebra of algorithms, the synthesized formulas of the algorithms are minimized by the number of unitherms. Also, in accordance with the properties of the formulas of the algorithms of algebra, the corresponding unitherms are taken out as signs of operations, as a result of which the formula of the algorithm for the synthesis of algorithm formulas is obtained taking into account the generation of subject unitherms based on abstract unitherms.
Real Estate Information Verification Service with the Use of the Blockchain Technology
Authors:   Lviv Polytechnic National University, Liubinskyi Bohdan , Ilnytskyi Valentine ,   Lviv Polytechnic National University, Topylko Petro ,   Lviv Polytechnic National University
Published: October 2021

Blockchain (blockchain — chain of blocks) — Distributed Ledger Technology (DLT). This is a combination of components that includes: peer-to-peer (P2P) networks, distributed storage, and cryptography (hashing and public-key encryption). Popular implementations of blockchain technology include Bitcoin as the electronic currency, which can be used to make money transfer transactions from one wallet to another. This paper considers Blockchain technology and the possibility of its usage to verify real estate information. There is a high demand today in the Ethereum platform for creating any decentralized online services based on blockchain (Dapps), working on smart contracts basis. Ethereum greatly simplifies and reduces the cost of implementing a blockchain. Representatives from various industries are interested in blockchain technology. These are mainly companies from different sectors of the economy, especially the banking sector, stock exchanges, etc. Also known applications of technology to the land register. It is implemented by both large players (Microsoft, IBM, Acronis, R3 banking consortium), and the new startups. The paper analyzes various types of real estate fraud and their impact. The requirements for building the architecture of the real estate information verification service have been collected. The architecture of the reasonable contract which considers all the requirements is offered. To implement the blockchain-based algorithm, a distributed Ethereum database based on smart contracts has been chosen. The built approach itself is based on the use of Blockchain technology. The architecture of the real estate information verification service has been developed using Blockchain technology, which, in turn, guarantees the successful execution of transactions and stable operation, which guarantees the entering, updating, and storing of real estate information and its verification.
Adaptive Software System Based on Ontological Approach for People With Cognitive Impairments
Authors:   Lviv Polytechnic National University, Fedasyuk Dmytro , Lutsyk Illia ,   Lviv Polytechnic National University
Published: October 2021

The paper presents a method of creating an adaptive software system to help people with cognitive impairments, based on the use of an ontological model of the subject area. The specifics of creating software tools to help people with cognitive impairments are analysed. The features of using the ontological approach for the formation of adaptive functionality and graphical interface are revealed and their advantages over traditional methods are analysed. It was found that when using this method, there is no need to recompile and fully deploy the software system in the event of a change in business logic. An ontological model of the subject area has been designed, which will make it possible to customize the system for the needs of a particular user. The architecture of a software system based on an ontological model of the subject area is proposed, which takes into account the possibility of personalizing the components of the system and the user interface without the need to re-deploy the system. The process of adaptation of a mobile application based on data about health disorders of the user using an ontological model of the subject area is disclosed. The result of the research is the development of a software system that implements the proposed adaptation process and allows to modify a mobile application for the needs of a specific user, using an ontological model of the subject area.
Analysis of Metrics for Intelligent Information Systems
Authors:   Lviv Polytechnic National University, Hryhorovych Viktor
Published: October 2021

The problem of constructing metrics is crucial for solving the problem of quantitative evaluation of both systems of objects of arbitrary nature as a whole and the relationships that describe the connections between the components of these systems. Modern information systems simulate subject areas that contain objects and systems of complex structure. The network model is most appropriate for describing the world around it: it reflects objects and systems of objects of arbitrary nature that interact with each other. In fact, any system can be described using a network model. Hierarchical models should be singled out as a kind of network models of complex systems. Hierarchical models are very widespread and are used in various fields — in biology, sociology, economics, technology, management, etc. — each industry has a set of its own hierarchical models. The paper analyzes metrics suitable for evaluating intelligent information systems, in particular — systems that are based on ontologies, non-relational (hierarchical) databases, non-normalized (nested) relationships.
Tietojärjestelmälääkärin toimenkuva ja koulutus Suomessa vuonna 2019
Authors: Laivuori Tove , Reponen Jarmo , Tuomiranta Mirja , Lääveri Tinja
Published: October 2021

Tietojärjestelmälääkäri tekee terveydenhuollon tietojärjestelmiin liittyvää työtä osana työnkuvaansa. Vuodesta 2012 lähtien lääkärit ovat voineet suorittaa Suomen Lääkäriliiton erityispätevyysjärjestelmän puitteissa terveydenhuollon tietotekniikan erityispätevyyden. Nykyään myös hammas- ja eläinlääkärit voivat hakea ohjelmaan. Terveydenhuollon tietotekniikkaan perehtyneiden ammattilaisten ja aiheeseen liittyvän koulutuksen tarve on kasvanut erityisesti viime vuosien nopean tietojärjestelmäkehityksen ja isojen tietojärjestelmähankkeiden myötä. Tästä huolimatta tietojärjestelmälääkärien roolia ja kokemuksia on tutkittu kansainvälisestikin hyvin vähän.
Keväällä 2019 toteutetun kyselytutkimuksen tarkoituksena oli kartoittaa tietojärjestelmälääkärien koulutustaustoja, työnkuvaa, työskentelyolosuhteita sekä terveydenhuollon tietotekniikan erityispätevyysohjelmaan liittyviä kokemuksia ja kehittämiskohteita. Kohderyhmänä olivat terveydenhuollon tietotekniikan erityispätevyyden suorittaneet, erityispätevyysohjelmaan ilmoittautuneet ja tietojärjestelmälääkärin työtä tekevät lääkärit ja hammaslääkärit.
Kyselyyn vastasi 90 henkilöä (54% kohderyhmän 167 lääkäristä/hammaslääkäristä), joista 27 työskenteli tietojärjestelmälääkärinä terveydenhuollon organisaatiossa ja 59 oli suorittanut erityispätevyyden. Tuloksia verrattiin soveltuvin osin vuonna 2014 toteutettuun kyselyyn (35 vastaajaa). Keskeisenä tuloksena oli, että verrattuna vuoteen 2014 tietojärjestelmälääkärien rooli ja tarve tunnistetaan organisaatioissa paremmin. Työtehtävät painottuivat tietojärjestelmien ja tiedonhallinnan kehittämiseen, ja työhön oli varattu enemmän työaikaa. Työnantajat suhtautuivat työpaikan ulkopuoliseen koulutukseen myönteisesti. Erityispätevyyden suorittamisen koettiin tuovan ammatillista hyötyä ja vaikutusmahdollisuuksia tietojärjestelmien kehittämiseen, mutta sen vaikutus työsuhteen ehtoihin jäi vähäiseksi. Erityispätevyysohjelmaan oltiin varsin tyytyväisiä, mutta teoreettiseen koulutukseen toivottiin strukturoitua runkoa.
Vahva kliininen osaaminen, laaja-alainen työkokemus ja erityispätevyys luovat hyvän pohjan tietojärjestelmälääkärin työssä tarvittavalle kokonaisvaltaiselle osaamiselle. Terveydenhuollon digitalisaation myötä tietojärjestelmälääkäreitä tarvitaan jatkossa yhä enemmän.
Potilastietojärjestelmiin liitetyt erikoisalakohtaiset erillisjärjestelmät julkisessa erikoissairaanhoidossa 2014–2020
Authors: Kenkimäki Heini , Keränen Niina , Haverinen Jari , Reponen Jarmo
Published: October 2021

Terveydenhuollossa on käytössä useita erilaisia tietojärjestelmiä. Niistä keskeisimpänä voidaan mainita potilastietojärjestelmät, joita käytetään niin potilaiden hoitotietojen kirjaamiseen kuin palvelujen ja toimenpiteiden ajanvaraamiseenkin. Terveydenhuollon tietojärjestelmiin kuuluvat oleellisina myös erillisjärjestelmät, jotka ovat erityistä toimintaprosessia tai erikoisalaa varten hankittuja järjestelmiä. Erillisjärjestelmiä on Suomessa eri lähteiden ja määritelmien mukaan kymmenistä jopa tuhansiin, ja erilaisten tietojärjestelmien suuri määrä ja pirstaloitunut tietojärjestelmäkokonaisuus haittaavat muun muassa kliinisen työn sujuvuutta.
Tämän tutkimuksen tavoitteena oli saada käsitys erillisjärjestelmien tuotemerkkien ja käytön tämänhetkisestä tilanteesta julkisessa erikoissairaanhoidossa sekä selvittää erillisjärjestelmien integraatioaste eli missä määrin ne ovat käytettävissä ydinpotilastietojärjestelmän kautta. Lisäksi tarkoituksena oli tehdä ajallista vertailua pyrkimyksenä muodostaa kuva siitä, mihin suuntaan erillisjärjestelmien käytössä ollaan menty ja mihin suuntaan mahdollisesti ollaan menossa. Tutkimus toteutettiin analysoimalla vuonna 2020 kerättyä terveydenhuollon organisaatiokyselyn osa-aineistoa sekä vertailemalla sitä vuoden 2017 ja 2014 aineistoihin vastaavilta osin.
Tutkimuksen perusteella erillisjärjestelmien integraatioaste on kasvanut vuodesta 2017 ja voidaan olettaa, että sen suunta on vastaisuudessakin samanlainen. Kolmen viimeisimmän kyselyn aikana erillisjärjestelmien käyttö eri erikoisaloilla on kaikkiaan yleistynyt sairaanhoitopiirien keskuudessa, ja käytössä olevien tuotemerkkien määrä on niin ikään pääasiassa lisääntynyt. Niiden osalta valtakunnalliset uudistukset ja hankkeet terveydenhuollossa saattavat kuitenkin muuttaa kehityksen suunnan jatkossa. Tulosten perusteella erikoisalakohtaisten erillisjärjestelmien käytön yleisyys sairaanhoitopiireissä ei kulje käsi kädessä tuotemerkkien määrän tai integraatioasteen kanssa, ja erikoisalojen välillä oli havaittavissa isojakin eroja näiden muuttujien osalta. Erillisjärjestelmien runsaasta määrästä voidaan päätellä, että erikoisalakohtaisten järjestelmien kliininen tarve on yhä olemassa. Laaja järjestelmäkirjo aiheuttaa kuitenkin haasteita, mikä ilmeni ristiriitaisissa vastauksissa koskien erityisesti integraatioastetta.