bluuebunny/crossref_metadata_2025 huggingface dataset:
Association Between the Managerial Ability and Long-Term Performance in Mergers and Acquisitions
Authors: Putri Adinda Ayu Jelita , Suryaningrum Diah Hari
Published: June 2022

Mergers and acquisitions are still a hot topic to be discussed and are often seen as a high priority issue worldwide as a controversial decision because it has a very complex impact. This study aims to test and analyze whether managerial ability has an effect on long-term performance and 1, 2, and 3 years after mergers and acquisitions. In addition, this study also aims to examine whether managerial ability in horizontal acquisitions has an effect on long-term operating performance rather than diversified acquisitions. This research uses quantitative research.  The sample of this research is 14 public acquisition companies with a research period of 10, 9, and 8 years after mergers and acquisitions are listed on the Indonesia Stock Exchange and KPPU in 2010-2012. The results showed that managerial ability had an effect on operating performance 1 year after mergers and acquisitions. Other research results indicate that managerial ability has no effect on operating performance 2 and 3 years after mergers and acquisitions and long-term performance. In addition, managerial ability in horizontal acquisitions has no effect on long-term performance and 1, 2, and 3 years after mergers and acquisitions than diversified acquisitions..
POSSIBILITIES OF RENOPROTECTION IN PATIENTS WITH CHRONIC KIDNEY DISEASE AND HYPERURICEMIA
Authors: Khimion Liudmyla V. , Burianov Oleksandr A. , Nayshtetik Iryna M. , Rotova Svitlana O. , Smiyan Svitlana I. , Danyliuk Svitlana V. , Trofanchuk Viktoriia V.
Published: June 2022

The aim: To determine efficacy and safety of allopurinol and febuxostat in treatment of patients with CKD to reduce the sUA level and analyze its influence on glomerular filtration rate (GFR).
Materials and methods: The study included 45 CKD patients (stages 3b-5) without other severe/decompensated diseases and contraindications to the allopurinol/febuxostat. All patients underwent a comprehensive clinical and laboratory examination, and were divided into the study groups: Group I (28 patients, 61,3±3,2 y.o., CKD3b-12, CKD4-10, on hemodialysis-6 patients) received febuxostat, Group II (24 patients, 60,7±4,1y.o., CKD3b-9, CKD4-10, on hemodialysis -5 patients) took allopurinol.
Results: Achievement of the target level of sUA was significantly often registered in Group I: after 1 month – in 45.5% (in group II – in 15.9%, p<0.001); after 3 months – in 67.5% (in group II – 21.2% p<0.01); after 6 months, these figures were 90% and 37.1%, respectively (p<0.01). sUA level <300 μmol/l was accompanied by significant positive GFR changes in group I patients; in group II there was a gradual progression of GFR deterioration in 31.8% of patients.
Conclusions: In patients with pre-dialysis stages of CKD febuxostat demonstrates renoprotective abilities. Use of febuxostat in patients with CKD stage 3b-4 and in patients on hemodialysis is safe and more effective for target sUA level achievement than the use of allopurinol.
HEPATIC VASCULAR TUMORS IN CHILDREN: POTENTIAL RISKS, OPTIMAL IMAGING AND THE ROLE OF SURGICAL INTERVENTION
Authors: Benzar Iryna M. , Levytskyi Anatolii F. , Diehtiarova Daria S. , Godik Oleg S.
Published: June 2022

The aim: To revise the case-series of hepatic vascular tumors (HVT), particularly to identify optimal visualization, management and role of surgical intervention.
Materials and methods: Out of 96 children with hepatic tumors who hospitalized in a single center from 2011 to 2020, 20 (20,8%) were diagnosed HVT. Hepatic Hemangiomas (HHs) were presented in 19 patients and Kaposiform hemangioendotelioma (KHE) in one case. To determine the type of HH we used radiological classification. For visualisation contrast-enhanced MRI (n=7, 30%) and cCT (n=15,70%) were used. Follow-up period was 14-77 months.
Results: All HVT were revealed by sonogram at the age of 0-5 m, with 4 (20%) diagnosed prenatally. Male to female ratio was 3:2. Beta-blockers were prescribed to 12 patients with HHs. Treatment duration was from 6 to 24 month. Steroid therapy was initial in cases when it was impossible to prescribe the curative dose of beta-blockers. Complications of propranolol treatment were transitory bradycardia (n=7) and transitory hypoglycemia (n=2). After vincristine chemotherapy decreases the tumor size by 54%, that allowed a safe liver resection. 4 (20%) patients – two multifocal HHs, one diffuse HH and in patient with KHE manifested congestive heart failure and pulmonary hypertension Mortality rate is 5% (n=1), this patient died against progressive cardiovascular failure.
Conclusions: life-threatening complication of HVT was congestive heart failure. Early treatment is beneficial for complications prevention. Surgical treatment is optional for KHE when can be removed safely.
IMPACT OF NUTRITIONAL CORRECTION OF PROTEIN METABOLISM DISORDERS ON THE CLINICAL COURSE OF PULMONARY TUBERCULOSIS
Authors: Galan Iryna O. , Protsyuk Radu G. , Omelchuk Sergii T. , Yeltsova Liubov B. , Bondarenko Yaroslava V. , Galan Alexander V.
Published: June 2022

The aim: To study the impact of nutritional correction of protein metabolism disorders on the clinical course of pulmonary tuberculosis.
Materials and methods: The study involved 67 patients with pulmonary tuberculosis, which were divided into two groups: group I – 35 patients who underwent nutritional correction of protein metabolism disorders against the background of antimycobacterial therapy (AMBT) and group II – 32 patients who received standard AMBT. An assessment of clinical indicators and the condition of protein metabolism (PM) was conducted by determining the concentration of individual non-essential, essential amino acids and their total amount.
Results: The proposed correction scheme includes food products containing essential nutrients and biologically active compounds that have a positive impact on the corresponding links of pathogenesis and can be used throughout all phases of treatment. Its application had a positive impact on the indicators of PM (significant (p<0.05) increase in total amount of essential amino acids (TAEAA), total amount of non-essential amino acids (TANEAA) and total amount of amino acids (TAAA) in blood serum and the concentration of individual essential and non-essential amino acids (significantly reached the level of indicators in healthy individuals) and clinical course of tuberculosis (intoxication syndrome disappeared earlier by 10.8 ± 0.97 days, and respiratory one by 8.95 ± 1.68 days), there was an increase in the frequency of healing of decay cavities at the time of completion of treatment by 34.0% and a significant (p<0.05) reduction in the average duration of treatment by 21.1±2.91 days.
Conclusions: The application of nutritional correction of protein metabolism in the complex treatment of patients with pulmonary tuberculosis made it possible to obtain a pronounced positive impact on the clinical course of the disease and the condition of protein metabolism, which contributed to an increase in the effectiveness of treatment and rehabilitation.
NATIONAL EXPERIENCE OF CREATING AND IMPLEMENTING MEDICAL STANDARDS IN CASE EVIDENCE APPEARS «LATER» (DURING THE COVID-19 CORONAVIRUS DISEASE PANDEMIC)
Authors: Dyachuk Dmytro D. , Stepanenko Alla V. , Lishchyshyna Olena M. , Zyukov Oleg L. , Oshivalova Olena O.
Published: June 2022

The aim: Identification of methodological processes to accelerate the development of clinical guidelines in an emergency situation (in particular, coronavirus disease COVID-19), analysis of the practice of implementing clinical guidelines and clinical pathway.
Materials and methods: The processes of developing COVID-19 clinical guidelines are described on the websites of the developers. Implementing the patient’s own clinical pathway. Survey of 117 health professionals involved in medical care at COVID-19 on management information. A retrospective pragmatic study of organizational and clinical aspects of medical care for 9,259 patients over 18 years with COVID-19 from March 18, 2020 to March 31, 2021.
Results: Acceleration of the methodology of clinical guidelines, changes in legislation have contributed to the improvement of medical care for patients with COVID-19. Clinical pathway (CPw) professionals surveyed: 88.2% satisfied with the structure of CPw, 91.0% were in favor of local instructions and explanations, templates of registration forms, 72.7% needed on-the-job training, 78.1% needed training on medical features, 74.5% noted the positive impact of remote interaction, 61.6% required standard operating procedures. 9259 patients with suspected COVID-19 confirmed PCR in 55.2%. Among those checked, 31.2% of chest computed tomography confirmed pneumonia in 95.7% of CT; 9.3% were hospitalized; fatalities 5.5% of hospitalized or 0.5% of verified.
Conclusions: Changes in the methodology of clinical guidelines, changes in legislation, education based on clinical guidelines have contributed to improving the results of management in COVID-19.
THE INFLUENCE OF THE REGULATORY SYSTEM ON THE STUDY DESIGN AND DATA MANAGEMENT PRACTICES IN CLINICAL TRIALS
Authors: Yashchenko Mariia V. , Yurochko Tetiana P. , Soroka Ivan M.
Published: June 2022

The aim: To review real-life regulatory-dependent study design and data management practices of post marketing multicenter studies of medical devices conducted in 2021 in Ukraine and Poland.
Materials and methods: This article presents the case study of 4 post marketing multicenter studies of medical devices conducted in 2021 in Ukraine and European Union.
Results: The case study presented effective cross-border cooperation between Ukrainian and European actors. Despite the gaps in Ukrainian legislative framework on medical devices, complex solutions on employment of the most stringent regulatory provisions led to appropriate study design. Usage of the highly compliant electronic data capture led to fast-track study start-up and solid clinical data collection.
Conclusions: Publications on real-life regulatory-dependent clinical trials conduct might be essential to innovate the regulatory system in Ukraine. The cross-border cooperation might assist the advancement of clinical trials industry in Ukraine. Gaps in medical devices regulations in Ukraine impede the context-specific clinical trials solutions for biotech industry in Ukraine. The regulatory framework and practice in Ukraine may be perceived as externally driven due to gaps in medical devices regulations, lack of capacities of domestic notified bodies and business interests of Sponsors.
DUAL TRIGGER STRATEGY AFTER CONTROLLED STIMULATION INTRAUTERINE INSEMINATION CYCLE DID NOT INFLUENCE THE PREGNANCY OUTCOME COMPARED WITH STANDARD HCG TRIGGER ONLY PROTOCOL
Authors: Thaker Ansam Zeki , Al-Anbari Lubna Amer , Al-Essawe Essraa Mohsen
Published: June 2022

The aim: A prospective randomized comparative study was conducted to investigate the effect of dual trigger, using gonadotropin releasing hormone agonist with human chorionic gonadotropin (hCG) versus hCG alone, for ovulation trigger in controlled ovarian stimulation intrauterine insemination (IUI) cycle on pregnancy outcome.
Materials and methods: Ninety women were randomly allocated into equal groups to trigger ovulation for IUI cycle using either method; IUI was performed following 36-42 hours post triggering. Luteinizing hormone (LH) and progesterone levels were measured at insemination day.
Results: The baseline of demographic and clinical characteristics of both groups was similar. Progesterone level was higher in dual trigger group than in hCG alone group (1.61 versus 0.71 ng/mL, P≤0.0001); while LH level was lower in dual trigger group (19.35 versus 24.51 IU/L, P≤0.014). Furthermore, LH level at the day of IUI was higher in pregnant women than in non-pregnant (27.9 versus 20 IU/L, P≤0.007).
Conclusions: Pregnancy rate was equivalent in both groups. More intensive investigation is required to study the efficacy of the dual trigger in IUI cycle.
FAT AND MUSCLE COMPONENTS OF BODY WEIGHT AND THEIR RELATIONSHIP WITH THE CONCENTRATION OF SERUM ADIPOKINES IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE
Authors: Pivtorak Kateryna , Fedzhaga Iryna , Pivtorak Natalya , Vozniuk Larysa , Klekot Olexandra
Published: June 2022

The aim: Identify differences in indexes of body fat and muscle masses, as well as blood adipokines in patients with nonalcoholic fatty liver disease, from gender-appropriate healthy men and women.
Materials and methods: 135 patients with non-alcoholic fatty liver disease with normal, overweight and obesity and 20 almost healthy individuals for the control group were examined. Verification of the diagnosis was performed in accordance with the recommendations of the unified clinical protocol. An anthropometric examination of patients was performed according to the method, which included the determination of 48 anthropometric parameters. The formulas determined the absolute amount of adipose and muscle tissue. Levels of adipokines (leptin and adiponectin) were determined by enzyme-linked immunosorbent assay.
Results: According to Matiegka, body fat was 30.2-35.2% higher, and muscle body weight was 17.4-29.1% lower in patients with non-alcoholic fatty liver disease compared to healthy people. The concentration of leptin in the serum of patients with nonalcoholic fatty liver disease was statistically significantly higher (2.05-3.78 times) compared with almost healthy individuals. At the same time, the indicators of adiponectin concentration (1.54-1.92 times) and log A / L index (1.16-1.32 times) were lower. Correlations between changes in muscle mass and adipokines concentration have been established.
Conclusions: In addition to the known increase in body fat in non-alcoholic fatty liver disease, there has been established a significant decrease in muscle mass. A direct correlation between adiponectin concentration and an inverse correlation between leptin levels and muscle mass in patients with nonalcoholic fatty liver disease was found.
THE ISSUE OF HISTOLOGICAL IDENTIFICATION OF М-CELLS IN THE PEYER’S PATCHES OF ALBINO RAT SMALL INTESTINE
Authors: Hryn Volodymyr , Kostylenko Yurij , Svintsytska Natalia , Bilash Valentуna , Lytovka Volodymyr
Published: June 2022

The aim: Based on the above cytological signs of M-cells, we set the goal of more detailed clarification of some of their topological relationships with other enterocytes in the follicle-associated epithelium of Peyer’s patches of albino rat small intestine.
Materials and methods: 10 mature albino male rats weighted 200,0±20,0 g were involved into the study. Anatomical dissection with the sampling of the sections of the small intestine containing Peyer’s patches was carried out with subsequent embedment of the latter into paraffin blocks and making of serial histological sections of 4 μm thick in the cross-section of the small intestine, followed with hematoxylin-eosin staining. The specimens were studied and documented on the “Konus” light microscope equipped. Morphometric characteristics of the specimen tissue structures were studied using the Sigeta X 1 mm/100 Div.x0.01mm stage micrometer.
Results: The findings of the study revealed enterocytes with phagocytic properties found in the lymphoid-associated epithelium of Peyer’s patches of the small intestine of albino rats. Moreover, if they are clearly visualized at the light-optical level, then M-cells are poorly recognizable, which is consistent with a similar assessment made by other authors.
Conclusions: Given this, the issue on the topology and functional purpose of M-cells remains uncertain to date and, thereby, the prospect of further research is being outlined, which, in our opinion, can be successful using the method of stereomorphological analysis. For this purpose, multilayer plastic reconstruction methods can be used for serial semi-thin sections of Peyer’s patches embedded in epoxy resin, according to the requirements of transmission electron microscopy.
CLINICAL AND IMMUNOLOGICAL FEATURES OF ROTAVIRUS INFECTION IN CHILDREN INFECTED WITH EPSTEIN-BARR VIRUS
Authors: Sliepchenko Marharyta Yu. , Kuznetsov Sergey V. , Kolesnyk Yana V. , Sorokina Olga G.
Published: June 2022

The aim: To identify clinical and immunological features of acute rotavirus gastroenteritis occurring against the background of Epstein-Barr virus infection.
Materials and methods: The study involved examination of 56 children. Of them, 33 children (1 group) did not have a background infection and 23 patients (2 group) suffered from rotavirus infection on the background of the latent form of Epstein-Barr virus infection. Children in these groups were compared by gender, age, severity of the disease and other parameters. Quantitative data were presented as mean and standard deviation (M±SD). Differences at p <0.05 were considered statistically significant.
Results: The data suggest that the presence of background Epstein-Barr virus in children with rotavirus infection leads to later hospitalization, lower temperature response rates, lower frequency of vomiting at the onset of the disease, and longer duration of fever and diarrhea. At the same time, in children infected with Epstein-Barr virus, the relative content of CD8+ T lymphocytes dominated both in the acute period of the disease and in the period of convalescence against the background of reduced relative content of CD16+, CD22+ T lymphocytes and IgM in the period of early convalescence.
Conclusions: The study allowed to reveal the influence of latent EBV infection on the clinical and immunological parameters of rotavirus gastroenteritis.
STRUCTURAL AND FUNCTIONAL FEATURES OF PERIPHERAL BLOOD ERYTHROCYTES AND ANTIOXIDANT PROTECTION ENZYMES IN PATIENTS WITH MULTIPLE SCLEROSIS
Authors: Popel Sergii , Gryb Viictoriya , Maksymchuk Liubov , Doroshenko Olexandr , Henyk Sofiia , Kupnovytska-Sabadosh Marta , Liskevych Iryna
Published: June 2022

The aim: The aim of this work is to study the structural and functional features of peripheral blood erythrocytes and antioxidant defense enzymes in patients with multiple sclerosis, depending on its clinical forms and the stage of development of the pathological process.
Materials and methods: The state of the processes of lipid peroxidation and the antioxidant defense system in 62 patients with multiple sclerosis was studied. The influence of these processes on the clinical manifestations of multiple sclerosis is shown.
Results: It has been shown that in multiple sclerosis, the erythrocyte superoxide dismutase / catalase enzyme system is characterized by the phenomenon of cross-regulation of activity, which is reflected in a negative correlation between enzyme activities and is associated with the appearance of irreversibly altered forms of erythrocytes in the general bloodstream.
Conclusions: Based on the analysis of the dynamics of laboratory parameters, the pathogenetic significance of membrane-destabilizing processes in peripheral blood erythrocytes of patients with multiple sclerosis was proved.
VESICAL IMAGING-REPORTING AND DATA SYSTEM – A NEW APPROACH TO BLADDER CANCER STAGING
Authors: Jakimów Krzysztof , Sznajder Katarzyna
Published: June 2022

The aim: To present the assumptions and to show the usefulness of Vesical Imaging-Reporting and Data System (VI-RADS) based on multiparametric magnetic resonance imaging (mpMRI) in the diagnostic pathway management of patients with a bladder cancer.
Materials and methods: The review is based on available literature from last 10 years from PubMed database and the Przegląd Urologiczny journal focusing on articles on VI-RADS. Overall, 18 articles were included. Presented magnetic resonance images come from the examinations of the patients who were diagnosed with bladder cancer from 2019 to 2021 at Department of Diagnostic Imaging in University Clinical Hospital in Opole, Poland.
Conclusions: The newly developed Vesical Imaging-Reporting and Data System has a potential to play a significant role in staging of the bladder cancer as a non-invasive, comprehensive, and effective diagnostic tool providing accurate information for differentiation non-muscle-invasive bladder cancer (NMIBC) from muscle-invasive bladder cancer (MIBC). However more prospective studies should be conducted to validate this system in clinical practice.
NEUROFIBROMATOSIS TYPE I AND ITS DIAGNOSTIC CRITERIA: A CLINICAL OBSERVATION
Authors: Purdenko Tеtiana I. , Delva Mykhailo Yu. , Ostrovskaya Liudmyla I. , Tarianyk Kateryna A. , Sylenko Halyna Ya. , Pushko Oleksandr O. , Purdenko Serhii V.
Published: June 2022

The aim – to consider the etiopathogenesis, the main clinical manifestations, diagnostic criteria of NF1, and present a clinical case from their practice. The paper analyzes the research findings in recent publications, focused on the studied issue using the methods of continuous sampling, synthesis and generalization, bibliosemantic evaluation and content analysis. In order to attract the attention of family physicians, neurologists, dermatologists, ophthalmologists, surgeons and other specialists, we present our own clinical observation of NF1.
The patient was examined using the methods of neurological examination, as well as other laboratory and instrumental methods of research. Early diagnosis and medical examination of patients with NF1 is crucial for predicting and improving the quality of life of patients. NF1 is a complex disease where the cooperation of doctors of different specialties is important. A favorable prognosis for patients is associated with the possibility of early diagnosis of malignant transformation and timely treatment.
TAFSIR HERMENEUTIK DAN FENOMENOLOGI DALAM AL-QURAN
Authors: Zubairin Ahmad
Published: June 2022

Al-Quran is the holy book of humanist Muslims. The entire content of the verse leads to humanizing humans, not the other way around. However, this noble goal has not been fully realized, it is allegedly by some circles because the methodology in the interpretation of the Qur'an still uses celestial language which is difficult to reason and apply. The interpreters of the Qur'an are still "preoccupied" with textual interpretations, even though if they borrow the humanities methodology, the interpreters will find a humanist interpretation, which is compatible with modern human values. Hermeneutics and Phenomenology are part of a humanist scientific methodology. Hermeneutics works by exploring the meaning behind the text of the scriptures, while phenomenology is an empirical method based on human phenomena with their reality. Both methods have a philosophical essence in their application, so that applying both methodologies in the study of the Qur'an is basically an effort to explore the deepest meaning of the Qur'an, which can usually be found in the interpretation of literary styles.
TREN KAJIAN TAFSIR AL-QUR’AN DI BETAWI DALAM MERESPON PERISTIWA POLITIK DI INDONESIA
Authors: Anwar Muhammad Khoirul
Published: June 2022

This article aims to reveal the portrait of the study of the interpretation of the Qur’an in Betawi, by taking case studies in several taklim assemblies in the Betawi community led by Betawi scholars. The question posed is, how is the dynamics of the study of Al-Qur’an interpretation in the Betawi community, especially when there is an issue of blasphemy against the former Governor of DKI Jakarta, Ahok? This article is written using Gadamer’s theory of interpretive constructs which includes elements of interpreter history, pre-understanding, text horizon and reading. This article shows that the study of Tafsir Al-Qur’an in the Betawi community has been running for several years. As in general, the Betawi people make mosques and prayer rooms as taklim assemblies or places to seek religious knowledge guided by ustaz or formerly known as mualiim. The pattern of the resulting study cannot be separated from the social background and education of the teacher, so that each object of this research has a distinctive character. The study method is taught thematically either following developing issues or by following the order of juz Mushaf Al-Qur'an.
Peranan Metode Pembelajaran Terhadap Minat dan Prestasi Belajar Peserta Didik
Authors: Abnisa Almaydza Pratama , Zubaidi Zubaidi
Published: June 2022

Learning as a process is designed by educators in creating a variety of innovative students who will be able to increase expertise in knowledge, and in order to build good mastery of learning material. Implementation in learning as the basis for formal learning in which there is communication between the various components of learning. The various components are divided into several categories including the following: the presence of educators, learning materials, and the presence of students. This component will require others such as the existence of media, methods, facilities and infrastructure, the existence of a management of the learning implementation environment, thus forming conditions for implementing existing learning that can achieve the targets of learning. Learning is the key for every individual to produce knowledge. So that knowledge learning can be achieved in a way that is consistent with the stages of individual growth. Learning is closely related to the life goals of students, and the goals will be different from one another. So learning should be carried out with systematic planning. Furthermore, in learning there is a process of guiding students, there is a process of changing directions, namely teaching provided by educators, while learning is carried out by students.
Intregritas Pendidikan Kolaborasi Berbasis Al-Qur’an Dalam Hubungan Kecerdasan Emosional Dan Perilaku Sosial Pada Mahasiswa Fakultas Teknik Universitas Islam 45 Bekasi
Authors: Fauzi Ahmad
Published: June 2022

This study uses a Qur'an-based collaborative education concept which then aims to test and find out empirical data regarding the relationship between emotional intelligence and social behavior with student collaboration skills in learning, either partially or simultaneously. This study uses a survey method with data collection tools using a questionnaire that is preceded by direct observation and interviews with data sources, namely undergraduate students of the Faculty of Engineering, Islamic University 45 Bekasi as the population. While the sampling in this study used a cluster sampling technique by taking the fourth semester students at the Faculty of Engineering, Islamic University 45 Bekasi, amounting to 70 students. The data analysis used is correlation and regression analysis which is described descriptively. The results of this study indicate that there is a positive and significant relationship between emotional intelligence and student collaboration skills in learning with a correlation coefficient of 0.917 and a coefficient of determination of 84.1%. Second, there is a positive and significant relationship between social behavior and student collaboration skills in learning with a correlation coefficient of 0.704 and a determination coefficient of 49.6%. Third, there is a positive and significant relationship between emotional intelligence and social behavior together with student collaboration skills in learning with a correlation coefficient of 0.919 and a coefficient of determination of 84.5%.
Türkiye’de Kadın Cinayeti Haberlerinin İçerik Analizi (2008-2021)
Authors: ASLAN Ayda , KIRIŞKAN İşın
Published: June 2022

Toplumsal olguların dayattığı cinsiyetçi rol paylaşımı başta aile olmak üzere toplumun tüm katmanlarında özümsenmekte ve içselleştirilmektedir. Dolayısıyla aile içinden tüm topluma yayılan cinsiyet eşitsizliği, kadınların ekonomik ve sosyal alanda birçok ayrımcılığa maruz kalmasına neden olmaktadır. Öte yandan, erkek egemen kültürün toplumda yarattığı kadın ve erkek arasındaki asimetrik güç ilişkisinden yani toplumsal cinsiyet eşitsizliğinden kaynaklanan kadına yönelik şiddet, kadının üzerindeki güç ve baskının daha da artmasına neden olmaktadır. Dolayısıyla kadına yönelik şiddet hem gelişmiş hem de gelişmekte olan ülkelerde görülen evrensel bir kalkınma sorunudur. Bu bağlamda kadına yönelik şiddetin bir sonucu olarak ortaya çıkan kadın cinayetlerinin yeniden üretilmesine neden olan değerler, mekanizmalar ve araçlar sorgulanmalıdır. Bu çalışmada, 2008-2021 döneminde, Türkiye’de kayıtlara geçen kadın cinayetleri, nitel ekonometrik yöntemler çerçevesinde değerlendirilmektedir. Bu amaçla, kayıtlara geçen kadın cinayetlerine ait haber verileri tek tek ele alınmıştır. Çalışmada toplam 4508 kayıtlı kadın cinayeti haber verileri kullanılarak, haberlerin medyaya yansıma biçimlerinden hareket edilerek haber içeriklerinin nitel analizi yapılmış ve Nvivo paket programı kullanılmıştır.
Improvement of PCF36Z + 316L clad steel welding technology in the construction of offshore stationary drilling platforms
Authors: Гальцов И.А. , Фомин Е.В.
Published: June 2022

В работе представлены результаты разработки новой технологии сварки ледового дефлектора, морской ледостойкой стационарной платформы, из плакированной стали PCF 36Z + 316L, с комплексным воздействием на металл сварочной ванны, заключающийся во введении в хвостовую часть жидкого металла сварного валика охлаждающей присадки и низкочастотных поперечных колебаний сварочной проволоки.Выявлено, что на образование сварного соединения тратится только четверть от общей теплоты дуги, а большая его часть расходуется на перегрев сварочной ванны, нагрев изделия, его деформацию, диффузию химических элементов между слоями. Эти процессы приводят к ухудшению структуры и свойств сварного соединения, значительному понижению качества сварных конструкций.Установлено, что использование комплексного способа дуговой сварки позволяет, увеличить площадь поперечного сечения сварного валика, уменьшить тепловое воздействие на металл, уменьшить количество проходов при формировании соединения, без увеличения погонной энергии сварки, обеспечить качественную, аустенитно-ферритную структуру сварных валиков переходного и плакирующего слоя.

The paper presents the results of the development of a new technology for welding an ice deflector, a marine ice-resistant stationary platform made of PCF 36Z + 316L clad steel, with a complex effect on the metal of the welding bath, consisting in the introduction of a cooling additive and low-frequency transverse vibrations of the welding wire into the tail part of the liquid metal of the welded roller.It is revealed that only a quarter of the total arc heat is spent on the formation of a welded joint, and most of it is spent on overheating of the welding bath, heating of the product, its deformation, diffusion of chemical elements between layers. These processes lead to deterioration of the structure and properties of the welded joint, a significant decrease in the quality of welded structures.It is established that the use of an integrated arc welding method allows to increase the cross-sectional area of the welded roller, reduce the thermal effect on the metal, reduce the number of passes during the formation of the joint, without increasing the linear welding energy, to ensure a high-quality, austenitic-ferritic structure of the welded rollers of the transition and cladding layer.
Failure’s analysis of marine diesel engines crosshead bearings
Authors: Полковников А.К. , Полковникова Н.А.
Published: June 2022

С повышением степени форсировки судовых малооборотных дизелей (МОД), ростом максимального давления сгорания проблема обеспечения надёжности подшипников и в первую очередь крейцкопфных остаётся актуальной. Рассмотрены конструктивные особенности крейцкопфных подшипников, предложены критерии оценки несущей способности и ударной нагруженности. В работе выполнен статистический анализ отказов, их причин и условий эксплуатации подшипников. При эксплуатации МОД наиболее эффективные меры, направленные на повышение работоспособности подшипников, связаны с выбором оптимальных режимов работы двигателя с целью ограничения действующей нагрузки и повышения запаса несущей способности подшипников. С износом и увеличением зазора в подшипнике несущая способность масляного клина снижается и возникает опасность появления полусухого трения и прогрессирующего износа. Усталостная прочность и долговечность подшипника определяется температурой антифрикционного слоя нижней (опорной) части вкладыша, для измерения которой была разработана система контроля температуры. Для непрерывного контроля технического состояния подшипников МОД высокую эффективность показала система контроля износов подшипников (Bearing Wear Monitoring System), которая измеряет комбинированный физический износ рамовых мотылёвых и крейцкопфных подшипников, обеспечивая раннее предупреждение об увеличении скорости износа вкладышей.

With an increase of forcing degree of marine low-speed diesel engines (MOD), an increase in maximum combustion pressure, the problem of ensuring reliability of bearings, and primarily crosshead bearings, remains relevant. The design features of crosshead bearings are considered, criteria for assessing the bearing capacity and shock loading are proposed. The paper considers a statistical analysis of failures, their causes and operating conditions of bearings has been carried out. The design features of crosshead bearings are considered, criteria for assessing the bearing capacity and shock loading are proposed. During the operation of the low-speed diesel engine, the most effective measures aimed at improving the performance of bearings are associated with the choice of optimal operating modes of the engine in order to limit the current load and increase the bearing capacity margin. With wear and an increase in bearing clearance the load-bearing capacity of the oil wedge decreases and there is a risk of semi-dry friction and progressive wear. The fatigue strength and durability of the bearing is determined by the temperature of antifriction layer of the lower (support) liner’s part, for the measurement of which a temperature control system was developed. For continuous monitoring of bearings technical condition, the Bearing Wear Monitoring System has shown high efficiency, which measures the combined physical wear of frame crank and crosshead bearings, providing early warning of an increase in the wear rate of liners.
Sperm DNA Fragmentation Index: A Comparison Study of Success Rates among Natural, Intrauterine Insemination (IUI) and In Vitro Fertilization (IVF)-Intra Cytoplasmic Sperm Injection (ICSI) Pregnancy Programs
Authors: Lestari Silvia Werdhy , Eva Zakiyah  , Gita Pratama
Published: June 2022

Background:   Some studies have reported a relationship between the sperm DNA fragmentation index (DFI) and the rate of fertilization and pregnancy. This study was designed to assess the mean sperm DNA fragmentation in pregnancies that occur in infertile couples, whether in natural pregnancy, intrauterine insemination (IUI), and in vitro fertilization (IVF) – intra cytoplasmic injection (ICSI).

Methods: This research is an observational analytic study with a cross-sectional design. The sample taken in this study were infertile patients that underwent natural pregnancy or IUI or IVF-ICSI at Yasmin Infertility Clinic of Dr. Ciptomangunkusumo Hospital period 2018-2020 with a consecutive sampling technique. The research data was processed and analyzed by the Mann-Whitney test using the SPSS application.

Results: The mean DFI of sperm in men with infertile couples who successfully conceived naturally was 10.7% (mild), while IUI was 20.4% (moderate), and IVF-ICSI was 30.5% (poor). The mean DFI in semen samples of men from infertile couples who underwent a natural program was significantly lower in those who successfully conceived compared to those who did not. Similar results were also shown in the IUI and IVF-ICSI programs, which showed a significantly lower DFI compared to non-pregnant women.

Conclusion: DFI can be applied as a marker for selecting the type of pregnancy program in infertility management.
Seasonal dynamics of soil Inorganic N and Nmineralization in sub-tropical Sal forest in Central Himalaya, India
Authors: Pandey Rachita , Singh Bargali Surendra , Bargali Kiran
Published: June 2022

Seasonal variation in inorganic N-pool and Net N-mineralization rate was investigated in relation to site characteristics in sub-tropical Sal forest in Central Himalaya, India. Two sites, viz. Fatehpur (FP) located at a latitude of 29°19'23.69''N and longitude of 79°18'05.34''E at 430 m asl and Ranibagh (RB) at a latitude of 29°17'10.03''N and longitude of 79°32'49.19''E at 580m asl were established. Ammonification, nitrification and Nmineralization rates were significantly (p<0.05) affected by site, season, soil depth and their interactions. Total inorganic -N and N-mineralization rates were significantly higher in FP site as compared to RB site. Higher mineralization rates were reported during the summer (7.30±0.17 μg g-1 month-1 and 6.17±0.27 μg g-1 month-1 in FP and RB site, respectively) and lowest rates during the winter season (2.10±0.17 μg g-1 month-1 ) in FP and (1.78±0.18 μg g-1 month-1 in RB site). The variability in mineralization rates may be due to the ecological differences among the sites. Seasons and soil nitrogen content showed positive correlation with Nmineralization rates while site, clay content and C/N ratio showed negative correlation. The soil Nmineralization affects the N release and availability of inorganic-N for supporting the plant growth, thus regulates the N- cycling in forest ecosystems.
Uprising in Upper Savoy in May 1793
Authors:   Institute of World History, Russian Academy of Sciences, Mitrofanov Andrey A.
Published: June 2022

In May 1793, a major popular uprising took place in Haute-Savoie, in the Ton Valley, which had important consequences for the region. At the time of recruitment into the army of the republic, residents of 13 communes of the valley near the city of Annecy entered into an armed confrontation with units of the French army and volunteers of the National Guard. The main slogans of the rebels were the abolition of the civil constitution of the clergy and conscription. The bulk of the rebels were peasants and artisans. The representative of the National Convention M.-J. Herault de Sechelles played a significant role in suppressing the uprising. Herault de Sechelles and the procureur-syndic of the district Annecy J.-C. Burnod. Marguerite Frischelet-Avet stood out especially among the leaders of the uprising. During the suppression of the uprising, the Republicans acted with extreme brutality and without observing any legal procedures. The uprising ended in defeat, but general political and social instability persisted in the Mont-Blanc department during 1793-1794.
Classical and Non-Classical Epistemology of Caves (Part 2)
Authors:   Northern (Arctic) Federal University named after M.V. Lomonosov, Varakin Vladimir S. , Openkov Mikhail Yu.
Published: June 2022

In the second part of the article, the authors “collect” the non-classical model of epistemology of caves, determining its paradigmatic specificity and characterizing the analytical approach that is fundamental to it. It is argued that the origins of this type of epistemology of caves can be found in antiquity as well, namely, in book 13 of Homer’s Odyssey and in the exegesis On the Cave of the Nymphs by Porphyry of Tyre, dedicated to a fragment in this book. In contrast to the classical, the non-classical model is defined as a glance-into-the-Beyond. From the authors’ point of view, the sensual Homeric cave turns the “darkness of the mystery” into the basic symbol of the non-classical epistemology of caves. Mystery is understood as the unrevealed or the unresolved, that is, something that transforms darkness into the “charming darkness”, i.e. into the synergy of the visible and the intelligible. As a result of the cognizer’s transitions into the depths of the “dark zone” of the cave, the latter loses its status as the Beyond, since darkness ceases to be the limit of cognition. Thus, the apophatic approach inevitably becomes the fundamental approach of the non-classical model. It is associated with the cognitive sciences, such as glaciospeleology and astrobiology. The authors step-by-step reveal the anthropological and spelestological dimensions of the non-classical epistemology of caves, focusing on the dominant – speleological and (more broadly) geological – dimension, which expands to the cosmic dimension. Caves and other cavities inside the Earth’s crust, primarily under the ocean floor and glacial layers, are considered not just as keepers of the mystery of the origin of life on Earth, but as models of such keepers on other planets of the Solar System and analogues of molecular clouds. It is emphasized that, due to the fixation on the search for the first principle of the nature of all matter, the non-classical model is rather close to early Greek philosophy, e.g. to the theories of Heraclitus of Ephesus. A conclusion for the two parts of the article is formulated: the anthropological dimension, which is key to both the classical and non-classical epistemology of caves, indicates the dynamics of redefining the role of the cave in human life.
Social “Coordinate Axes” and Coordinate Thinking in Humanities Research
Authors:   Northern (Arctic) Federal University named after M.V. Lomonosov, Makulin Artem V.
Published: June 2022

This article describes the methods of graphic modelling of social phenomena and the general ideological foundation of visual-spatial thinking on the basis of coordinate and matrix analysis. The paper presents the cases of applying the coordinate axes method in social and political philosophy, which determine the variable vectors of understanding the social in general and its individual elements in particular. Specifically, the experience of synthesizing social matrices and coordinate axes is considered not only as a convenient way to visualize some of the points of socio-philosophical analysis, but also as a methodology for mental experimentation aimed at expanding the range of views on the chosen issue. coordinate modelling is analysed by the author as an important methodological technique in the study of social phenomena, overcoming the abyss of interdisciplinarity. This makes it possible to draw conclusions by analogy by transferring cognitive methodological structures that are neutral in terms of content from one field of knowledge to another, thereby providing fresh perspectives on the existing patterns of thinking and on the analysis of social phenomena. This paper does not claim to present a holistic study of the problems of the formalized representation of socio-philosophical concepts using the graphic language of axes and matrices, but simply points out possible ways of heuristic mediation of complex theoretical constructs by elements of graphic modelling. The article concludes by underlying the importance of using graphic techniques while working with information, concepts and theories for heuristic interpretation and epistemological restructuring of socio-philosophical problems.
THE IMAGE OF THE CITY IN THE NOVEL WEI HOYA 卫慧 "MARRIED TO A BUDDHA 我的神"
Authors:   Senior Lecturer Tashkent State University of Oriental Studies Tashkent, Uzbekistan, Nazirova Sh. M.
Published: June 2022

The article highlights and discusses the image of the city in the novel "WEY HOYA CHUNNI" "BUDDHA MARRIED"
GROUNDWATER AND GREAT WATER MANAGEMENT IN DRY AREAS OF UZBEKISTAN
Authors:   Master's student Jizzakh State Pedagogical Institute Jizzakh, Uzbekistan, Qabulova Latofat
Published: June 2022

This article systematizes and analyzes the issues of rational use and protection of groundwater in arid regions of Uzbekistan.
ECOLOGICAL SITUATION AROUND THE AYDAR-ARNASOY LAKE SYSTEM AND WAYS TO IMPROVE IT
Authors:   Master's student Jizzakh State Pedagogical Institute Jizzakh, Uzbekistan, Nishanov Ulugbek Q.
Published: June 2022

This article examines the issues of environmental degradation in the Aydar-Arnasay lake system, measures to prevent them, the development of ecotourism and ongoing monitoring.
PROSPECTS FOR THE DEVELOPMENT OF ECOTOURISM IN PROTECTED NATURAL AREAS
Authors:   Researcher Jizzakh State Pedagogical Institute Jizzakh, Uzbekistan, Toshboev Z.M. , Urozaliev I.M. ,   Researcher Jizzakh State Pedagogical Institute Jizzakh, Uzbekistan, Khamzaev J.R. ,   Researcher Jizzakh State Pedagogical Institute Jizzakh, Uzbekistan
Published: June 2022

Today in our country much attention is paid to the development of ecotourism in specially protected natural areas, there is a growing interest in its study in order to develop ecotourism. This article discusses the importance of developing ecotourism in protected natural areas.
NATURAL HYDROGRAPHY OF JIZAK REGION AND GEOGRAPHICAL ASPECTS OF THEIR EFFECTIVE USE
Authors:   Lecturer Jizzakh State Pedagogical Institute Jizzakh, Uzbekistan, Kholmirzaev .E. , Qosimov N.D. ,   Lecturer Jizzakh State Pedagogical Institute Jizzakh, Uzbekistan, Khakimov B.B. ,   Lecturer Jizzakh State Pedagogical Institute Jizzakh, Uzbekistan
Published: June 2022

This article analyzes the natural hydrography of Jizzakh region, rivers, streams and geographical aspects of their efficient use.
COOPERATION OF RENEWABLE UZBEKISTAN WITH THE CIS COUNTRIES IN THE FIELD OF HIGHER EDUCATION (2017-2021)
Authors:   Candidate of Historical Sciences, Associate Professor National University of Uzbekistan named after Mirzo Ulugbek Tashkent, Uzbekistan, Siddiqov Ravshan B.
Published: June 2022

This article analyzes the role and further expansion of international cooperation in the development of higher education in the updated Uzbekistan on the basis of the "Action Strategy" adopted in 2017. The main attention is paid to highlighting the comprehensive cooperation of Uzbekistan with the CIS countries, Russia and Belarus in the field of higher education and in the training of highly qualified personnel. The activity of branches of leading foreign universities established in this field has been studied. The issues of training modern personnel and scientific cooperation for the needs of Uzbekistan on the basis of joint programs and roadmaps with leading foreign universities were also highlighted.
CHACH IS THE ADMINISTRATIVE CENTER OF THE WESTERN TURKISH KHANATE
Authors:   Senior Lecturer, PhD National University of Uzbekistan Tashkent, Uzbekistan, Mukhamedov Yakubdjan K.
Published: June 2022

This article analyzes the activities of Chach as the administrative center of the Western Turkic Khanate during the early Middle Ages based on archeological and written sources. The article describes the administrative management of the oasis by comparing the views of foreign researchers on the activities of the economic, political and administrative centers of the oasis with the data in written sources.
DEVELOPMENT CHARACTERISTICS OF THE MIDDLE EAST IN THE CONTEXT OF GLOBAL CHANGE
Authors:   Candidate of Political Science, Associate Professor Tashkent State University of Oriental Studies Tashkent, Uzbekistan, Madaminova Durdona
Published: June 2022

This article analyzes the specific development features of the Middle East region in the context of globalization, internal and external factors affecting them. The article reveals the specific stages of development of the Middle East, the peculiarities of the formation of national state structures, the harmony of language, religion and culture in the development of the region, the internal factors influencing the development of relations with the outside world on the basis of comparative political and historical methods.