bluuebunny/crossref_metadata_2025 huggingface dataset:
An integrated strain-level analytic pipeline utilizing longitudinal metagenomic data
Authors: Zhou Boyan , Wang Chan , Putzel Gregory , Hu Jiyuan , Liu Menghan , Wu Fen , Chen Yu , Pironti Alejandro , Li Huilin
Published: September 2022

Background
With the development of sequencing technology and analytic tools, studying within-species variations enhances the understanding of microbial biological processes. However, most existing methods for strain-level analysis do not allow for the simultaneous interrogation of strain proportions and genome-wide variants in longitudinal metagenomic samples.
Results
In this study, we introduce LongStrain, an integrated pipeline for the analysis of large-scale metagenomic data from individuals with longitudinal or repeated samples. In LongStrain, we first utilize two efficient tools, Kraken2 and Bowtie2, for the taxonomic classification and alignment of sequencing reads respectively. Then, we propose to jointly model strain proportions and shared haplotypes across samples within individuals, which greatly improves the efficiency and accuracy of strain identification. With extensive simulation studies of a microbial community and single species, we show that LongStrain is superior to three popular reference genome-based methods in variant calling and strain-proportion estimation. Furthermore, we illustrate the potential applications of LongStrain in the real data analysis of The Environmental Determinants of Diabetes in the Young study and a gastric intestinal metaplasia microbiome study.
Conclusions
The proposed analytic pipeline demonstrates marked statistical efficiency over same type of methods and has great potential in understanding the genomic variants and dynamic changes at strain level.
Topical application of an irreversible small molecule inhibitor of Lysyl Oxidases ameliorates skin scarring and fibrosis
Authors: Chaudhari Nutan , Findlay Alison , Stevenson Andrew , Clemons Tristan , Yao Yimin , joshi Amar , Sayyar Sepidar , Wallace Gordon , Rea Suzanne , Toshniwal Priyanka , Deng Zhenjun , Melton Philip , Hortin Nicole , Iyer Swaminatha , Jarolimek Wolfgang , Wood Fiona , Fear Mark
Published: September 2022

Scarring is a lifelong consequence of skin injury, with scar stiffness and poor appearance presenting physical and psychological barriers to a return to normal life. Lysyl oxidases are a family of enzymes that play a critical role in scar formation and maintenance. Lysyl oxidases stabilize the main component of scar tissue, collagen, and drive scar stiffness and appearance. Here we describe the development and characterisation of an irreversible lysyl oxidase inhibitor, PXS-6302. PXS-6302 is ideally suited for skin treatment, readily penetrating the skin when applied as a cream and abolishing lysyl oxidase activity. In murine models of injury and fibrosis, topical application reduces collagen deposition and cross-linking. Topical application of PXS-6302 after injury also significantly improves scar appearance without reducing tissue strength in porcine injury models. PXS-6302 therefore represents a promising therapeutic to ameliorate scar formation, with potentially broader applications in other fibrotic diseases.
Occlusion-robust workflow recognition with context-aware compositional ConvNet
Authors: Zhang Min , Hu Haiyang , Li Zhongjin , Chen Jie
Published: September 2022

Workflow recognition relying on deep convolutional neural network has obtained promising performance. Though impressive results have been achieved on standard industrial workflow, the performance on heavily occluded workflow remains far from satisfactory. In this paper, we present an effective context-aware compositional ConvNet (CA-CompNet) for occluded workflow detection with the following contributions. First, we combine compositional model and original ConvNet together to build a unified deep architecture for occluded workflow detection, which has shown innate robustness to address the problem of object classification under occlusion. Second, in order to overcome the variable occlusion limitations, the bounding box annotations are utilized to segment the context from target workflow instance during training. Then, these segmentations are used to learn the proposed CA-CompNet, which enables the network to untangle the feature representation of workflow instance from the context. Third, a robust voting mechanism for candidate bounding box is introduced to improve the detection accuracy, which facilitates the model to precisely detect the bounding box of a specific workflow instance. Comprehensive experiments demonstrate that the proposed context-aware network can robustly detect workflow instance under occlusion in industrial environment, increasing the detection performance on MS COCO dataset by 1.4% in absolute performance compared to the advanced CenterNet.
Comprehensive analysis of the association between human diseases and water pollutants
Authors: XinluJiang  , Ding Kaiyang
Published: September 2022

Drinking water is an important natural resource. For many people around the world, especially in developing countries, access to safe drinking water is still a distant dream. An increasing number of human activities and industrialization have caused various physical, chemical and biological pollutants to enter water bodies, affecting human health. Efforts to figure out an effective method to predict water pollution poisons and human diseases have increased worldwide. Water pollutants contain a vast number of additives such as perfluorinated chemicals, polybrominated diphenyl ethers, phthalate, nanomaterials, insecticides, microcystins, heavy metal and pharmacologies. Here, we explored an integrative approach to identify genes, biological processes, molecular functions, and diseases linked to exposure to these water pollutants. These processes and functions affected by water pollutants are related to the many diseases, including colonic neoplasms, breast neoplasms hepatitis B, bladder cancer and human cytomegalovirus infection. Therefore, conducting an integrative toxicogenomic analysis of water pollutants are more appropriate for evaluating the potential effects of plastics in human health.
The Topographic Representation of Time and its Link With Temporal Context and Perception
Authors: Kulashekhar Shrikanth , Fortunato Gianfranco , Maass Sarah , Rijn Hedderik van , Bueti Domenica
Published: September 2022

Neuronal tuning and topography are mechanisms widely used in the brain to represent sensory information and also abstract features like time. In humans, temporal topography has been shown in a wide circuit of brain regions. However, it is unclear whether chronotopic maps are specific to vision, whether they map time in an absolute or relative fashion, to what extent they reflect objective or subjective time and whether they are influenced by temporal context. Here we asked human participants to reproduce the durations of sounds in two, partially overlapping, temporal contexts while we record high-spatial resolution fMRI. Both model-based and data driven analyses show the presence of auditory chronomaps in the auditory parabelt, intraparietal sulcus, and in supplementary motor area. Most importantly, when the same physical duration is presented in different temporal contexts, and thus perceived differently, different neuronal units respond to it. Those units are also spatially shifted according to the relative position of the perceived duration within each context. Finally, the pattern of activity is more similar within rather than across contexts suggesting their pivotal role in shaping the maps. These results highlight two important properties of chronomaps: their flexibility of representation and their dependency on the context.
Tackling corruption in the health sector
Authors: Bozhenko Victoria
Published: September 2022

Corruption in the health sector is unique because it includes abuse by public officials and unscrupulous behavior by other actors (drug manufacturers, health professionals, patients, etc.). The urgency of solving the scientific problem lies in the fact that financial relations in the medical field arise between a wide range of persons who can act as initiators of corruption decisions and/or their executors. The study’s main goal is to analyze the forms of corruption in the healthcare system and their consequences for society, as well as to assess the degree of interrelationship between the level of corruption and indicators of financial support in the healthcare sector. The methods of structural and comparative bibliometric analysis and correlation analysis became the methodical tools of the conducted research. The object of research is 140 countries in the world. The conducted bibliometric analysis testified to the permanent growth of the study of the issue of corruption in medicine in the scientific environment. Scientists from the United States, United Kingdom, and Germany have implemented the largest number of works on a certain topic. The conducted correlation analysis also empirically confirmed that an increase in the level of corruption in the country leads to an increase in the share of household expenses for financing their own medical needs. The article founds that the population in countries with a low level of corruption (the corruption promotion index is closer to 100) has a higher level of provision of vital medical services (reproductive health, health of women, newborns, and children, infectious diseases, non-infectious diseases and opportunities provision of services and access to them). Countries with a high level of anti-corruption and coverage of medical services include Finland, Sweden, Germany, and Great Britain. The results of the research can be useful for state regulatory bodies, specialized organizations in the field of health care, as well as public organizations.
Social Learning Theory in Clinical Setting: Connectivism, Constructivism, and Role Modeling Approach
Authors: Khushk Amir , Dacholfany Muhammad Ihsan , Abdurohim Dindin , Aman Nasir
Published: September 2022

The purpose of this study is to explore the social learning theory in terms of connectivism, constructivism, and role modeling approach in a clinical setting and its consequences. This article aims to analyze the possible role of connectivism, constructivism, and, role modeling as learning theories in terms of dealing with useful student learning instructional strategies. All these approaches are key concepts to align any level of education (primary, secondary, and particularly higher education). The research is qualitative in design and uses an inductive approach. Using a qualitative content analysis approach enables in-depth study of studies as well as data interpretation, leading to conclusions regarding the meaning of diverse experiences. The authors have given insight into designing teaching practices that adapt to changes in how management, physicians, and medical students observe, learn, communicate, generate and share new knowledge. The current study provides a summary of approaches and theoretical insights about planned and unplanned learning. This research will be valuable in developing role modeling instructional programs. Encouraging clinical instructors to make continual efforts to enhance role modeling and teaching time management and self-control skills can assist clinical teachers to overcome the problems of learning with role modeling. The finding shows that collective learning outperforms individualistic learning in terms of improving engagement, enhancing quality, and producing positive interpersonal outcomes. Encouraging clinical instructors to make continual efforts to enhance role modeling and teaching time management and self-control skills can assist clinical teachers to overcome the problems of role modeling. The building is a theory that affirms that learning is a process for the learner Role modeling is effective for medical students. The implications and future directions would be beneficial for researchers and academicians seeking to empirically extend their study on connectivism, constructivism, and role modeling approaches.
Measurement of Visitors’ Satisfaction towards Health Tourism: Structural Equation Modeling Analysis
Authors: Afzal Hossain Afzal Hossain
Published: September 2022

Health tourism is an emerging concept in the tourism industry. Health tourism is the act of traveling to obtain medical care. Health tourism is also a unique thought in the travel and tourism industry. It plays a vital role in the tourism sector. A large number of people travel for treatment every year. Health tourism helps to develop the economy and living standards of human civilization. Health tourism is a market combination of the healthcare and tourism sectors. Health tourism is growing day by day internationally as well as nationally. When people travel to a foreign region to get medical treatment, many issues and challenges arise. Health tourism facilitators play a crucial role in the health tourism sector. Health tourism facilitators also play a significant role in making the medical travel easy and comfortable. In the country of destination, health tourism encourages economic development and raises the quality of healthcare provided. In many of these developing countries, health tourism represents a lucrative and growing source of economic revenue. Therefore, the purpose of this research was to use partial least square structural equation modeling (PLS-SEM) to measure the visitors’ satisfaction towards health tourism in the perspectives of Bangladesh. This research used both quantitative and descriptive analysis methods. A standardized questionnaire was used to collect 205 data points from Bangladeshi visitors using a purposive sampling technique. A partial least square structural equation modeling (PLS-SEM) approach was used to measure the data and test the hypotheses. The results of the PLS-SEM method revealed that product, place and process had a significant and positive influence on visitors’ satisfaction towards health tourism in the perspectives of Bangladesh. The results of the research can offer value insights for academicians to do future authorizations. It can be also helped for practitioners to design suitable marketing strategies for visitors’ satisfaction towards health tourism as a destination in Bangladesh.
Checklist for Professional Communication: A Path to a Healthy Personality, Reflective Mindfulness, and Self-Development Management
Authors: Mujtaba Bahaudin G. , Meyer Chance
Published: September 2022

Have you ever had multiple goals and aspirations at once? Psychologically, planning a written list and working through the plan is likely to lead to more productivity than simply dreaming about achievements. Professionals in many disciplines use written checklists to ensure productivity and safety in the workplace. For example, Dr. Atul Gawande’s checklists for the healthcare industry have improved healthcare outcomes for many patients by reducing errors and getting things done more efficiently. We can all use similar checklists as touchstones or reminders to increase our efficiency and engagement in pursuing our own goals and thus to improve our own personal outcomes through greater sensemaking and mindfulness. In this article, we undertake a literature review identifying and synthesizing key concepts from various areas of organizational and leadership theories to provide a broadly valuable basis for constructing a professional and personal development checklist. Professional communication is about representing yourself in the best sense of your character, image, and abilities through sensemaking, collaboration, storytelling, listening, and effective conflict management practices. Having a professional checklist works best when it is aligned with your true inner character as well as outward personality and social identity. Professional communication is about being sincere, principled, deliberate, meaningful, and authentic in all circumstances. The key is to balance your life’s important values-based priorities and be yourself, instead of acting as someone you are not. In other words, focus on the deontological view of ethical decision-making, as opposed to always leaning toward the teleological or consequentialism perspective. People often attribute their own moral or amoral decisions and behaviors to situational factors. The reality is that the human mind is a complex biological machine that is programmed and reprogrammed from the time of one’s conception until the day we die. The complexity of genetic and environmental factors, socialization under different circumstances, and lived experience across culture and opportunity mean people have varied capacities to make choices and attributions. As professionals, we all play the cards we are dealt and the more effectively and strategically we use these “cards,” the better will be the future outcomes. Human behavior is often influenced and driven by factors that we might not fully understand, but we must make the best use of what we do comprehend at any given time before the opportunity is gone. Science has proven that the use of an appropriate checklist for personal development can lead to productivity, professional career success, better work-life balance, and personal happiness.
Hemoglobinopathies by HPLC: A 3 Year Study of 106,277 Cases
Authors: Joshi Amruta , Gohil Sanjay , Saxena Bhavya , Jatale Raj , Chadha Kirti , Haryan Reshma , Patil Priya , Chanekar Milind
Published: September 2022

Introduction: Hemoglobinopathies and thalassemias are the most common single gene disorders in the world. World Health Organization figures estimate that 5% of the world populations are carriers of a potentially pathological hemoglobin (Hb) gene. The general incidence of thalassemia trait and sickle cell anaemia in India varies between 3-17% and 1-44% respectively3 but because of consanguinity, caste and area endogamy, some communities show a very high incidence, making the disease a major public health problem in our country. Cation exchange high-performance liquid chromatography (CE-HPLC) is one of the best methods for screening, detection, and identification of various hemoglobinopathies.

Material &Method: A retrospective study was carried out from period of 2017 to 2019 with 106277 cases evaluated with an aim to identify various hemoglobinopathies seen in Indian population by high-performance liquid chromatography. Cases outside Indian geographical location were excluded from the study

Result: A total of 18,936(17.82%) cases with abnormal haemoglobin variants was reported in the study with 35 difference variants across India. Northeast India reported maximum abnormal hemoglobinopathies (50.16%). Beta Thalassemia Trait was the most common abnormal variant found.Such a high incidence emphasises premarital and prenatal screening for prevention of dangerous effects of hemoglobinopathies in the population.

Conclusion: CE-HPLC should be used for early detection and proper management of these haemoglobinopathies. The most common hemoglobinopathy observed in our study was Beta thalassemia trait followed by Sickle cell trait and then sickle cell disease. It was also observed that Northeast India had maximum abnormal hemoglobinopathies.
Sinonasal Intestinal Type Adenocarcinoma Involving the Paranasal Sinuses: A Rare Case Report.
Authors: Chintalapudi Deepthi Chandrika
Published: September 2022

Sinonasal intestinal-type adenocarcinomas (ITAC) are very uncommon, with an overall incidence of <1 case per 1 million person-years and prevalent among people who work for prolonged periods in wood or leather industries. Here, we present a rare case of sinonasal intestinal-type adenocarcinoma in a 38yr old male.
„Miért olyan nehéz?” Az egészséges életmódra való áttérés akadályai és a változtatás lehetőségei – szakirodalmi feldolgozás
Authors: Szabó Imola , Lehota József
Published: September 2022

Az egészség a magyarok számára a legfontosabb érték, ám ennek megvalósítása komoly problémákba ütközik. Az étkezési szokásokban az íz dominanciája felülír minden más tényezőt, miközben az egészséges étkezést drágának, nehezen kivitelezhetőnek tartják a fogyasztók. Az alacsony szintű zöldség-gyümölcs fogyasztás is jellemző a magyar lakosságra, ahogy a mozgásszegény életmód is. A lakosság egynegyede mindennap dohányzik, 6,3% mindennap alkoholt fogyaszt, 19% pedig hetente, de nem minden nap. A magyar lakosság nagyjából fele krónikus betegséggel küzd. Hasonló kórképet figyelhetünk meg Európa más országaiban, valamint az Amerikai Egyesült Államokban is. Azonban a helyzet javítható a fogyasztó elköteleződésével, a motiváció elősegítésével, megtartásával, amely éppúgy fontos, mint a külső támogatottság. Ha társadalmilag nagyobb hangsúly helyeződik az egészséges életmódra, a fogyasztói elköteleződés is tartósabb lesz. Külső és belső hatások nélkül nehéz a társadalmat az egészségesebb élet felé mozdítani, ám ezek együttes hatásával elindulhat a változás.
Az önkormányzatok által működtetett tulajdonosi kontroll megvalósítása
Authors: Menich-Jónás Judit
Published: September 2022

Az önkormányzati tulajdonú gazdasági társaságok olyan államháztartáson kívüli szervezetek, amelyek közfeladatokat látnak el, közpénzt is felhasználnak, de nem a költségvetési gazdálkodás szabályai, hanem a gazdasági társaságoknak előírt jogszabályok szerint gazdálkodnak. Ezért az átlátható, eredményes és hatékony működés kereteit a tulajdonos önkormányzat jegyzőjének kell kialakítania, a tulajdonosi kontroll szabályokon keresztül, akár a jogszabályi előírásoknál szigorúbb kötelezettségeket is előírva. A tanulmány keretében bemutatom, hogy az elmúlt 10 évben milyen változások mentek végbe az önkormányzati tulajdonosi joggyakorlás tekintetében. Fontos mérföldkő volt egy 2011-es törvénymódosítás, amely lehetővé tette az Állami Számvevőszék számára, hogy az önkormányzati tulajdonú gazdasági társaságokat is ellenőrizze. A 2011-2016. között lefolytatott ellenőrzési tapasztalatokról kiadott elemzésekből kiindulva megvizsgáltam, hogy változott-e az önkormányzatok által folytatott gyakorlat a tulajdonosi kontrollok kiépítése és megvalósítása tekintetében. Kutatásom alapján megállapítható, hogy a helyi önkormányzatok által működtetett tulajdonosi kontroll tekintetében némi fejlődés tapasztalható.
COVID-19 Impact on Syrian Refugees Employability in Jordan
Authors: Jarrar Doa Mazen Fahmi
Published: September 2022

Jordan, a country with a high population of refugees, has become one of the most affected countries with the recent refugees’ crisis today. Increasing the loads on a country that already suffers from a high unemployment rate. As a result, Jordan has adopted strict labour regulations concerning the employment of foreign workforce including refugees, to ensure that Jordanian citizens are given a priority in accessing the job market first. Therefore, Syrian refugees are not only facing the difficulties that already existed since their arrival to Jordan, but also an additional burden that was added with the pandemic caused by COVID-19. Accordingly, this study aims to explore the impact of COVID-19 on Syrian refugees’ employability, through answering the research questions of: What was the impact of COVID-19 pandemic on the Syrian refugees’ employability? How did the different defence orders in Jordan affect the employability and/ or the financial income of the Syrian refugees? And were the Syrian refugees benefited from any additional financial assistance? Furthermore, the study was conducted after ten months of the start of the pandemic situation caused by COVID-19 in Jordan. Therefore, the refugees’ employability was assessed as before, during and after the strict pandemic lockdown.
The Impact of Contextual Factors of Silence on Employees’ Satisfaction in the Jordan Ministry of Education
Authors: Alkhlaifat Osama Khaled Ahmad
Published: September 2022

This research aims to determine the impact and relationship direction between organizational silence and employees’ satisfaction in the Jordanian Ministry of Education (MOE). The study used a questionnaire tool that was developed based on previous studies. The questionnaire was distributed to 100 employees randomly. The alpha coefficient was used to test the reliability of the instrument. Also, multi-regression and the One-way ANOVA analysis were used to examine the hypotheses. The results showed that the sample reported a moderate degree of both silence and satisfaction and that the relationship is inverse between the organizational factors of silence and job satisfaction. The results also showed that the “Lack of support” factor was the most influential factor and the “Mistrust” had the lowest impact on satisfaction.
Recenzió az „AMI VAGYON, AZ LEGYEN IS” – tanulmánykötet a jövedelemadózásról című műhöz
Authors: Bosnyák Edit , Gácsér Norbert György
Published: September 2022

Kenyeres, S., Kovács, T., & Vágyi, F. R. (2020). Ami vagyon, az legyen is. (S. Kenyeres, T. Kovács, & F. R. Vágyi, Eds.). Sopron: Soproni Egyetem Kiadó
Vándorló magyarok, avagy mit mutatnak az adatok?
Authors: Obádovics Csilla
Published: September 2022

Az uniós csatlakozás, a határnyitás, majd a munkaerőpiac megnyitása a magyarok számára komoly lehetőséget jelentett a jobb kereseti lehetőségek tekintetében. Sok fiatal és aktív korú tanulás, munkavállalás és tapasztalatszerzés céljából távozott a nyugati országok valamelyikébe, legtöbben Németországba, az Egyesült Királyságba és Ausztriába. 2011 után, a bevándorlási regisztráció szigorítása óta lényegesen megnőni látszik a Magyarországra be-, illetve visszavándorlók száma. A visszavándorló magyar állampolgárok mellett a külföldön született magyar állampolgárok bevándorlása is jelentősen megemelkedett. Nem lényegtelen azonban, hogy a vissza-, illetve bevándorló magyarok milyen életkori kategóriába tartoznak. Megállapítottuk, hogy a szomszédos országokból bevándorlók életkori megoszlása között jelentős eltérés tapasztalható. Szlovákiából jellemzően a 60 év felettiek, míg Romániából a 30-49 éves korosztály a legjelentősebb bevándorló korcsoport. Megvizsgáltuk a Magyarországra való áttelepülés motivációit mind a külföldi, mind a magyar állampolgárok esetében. A visszatérő, Magyarországon született magyar állampolgárokról összességében elmondható, hogy alapvetően a családi ok az a motiváló tényező, ami miatt hosszabb idő után is hazavándorolnak a magyar állampolgárok. Rövidebb idő után, illetve egyéb országokból a cél teljesülése a legjelentősebb visszavándorlási ok.
Industrie 4.0 in Transport und Logistik : Enabler, Hürden und Auswirkungen
Authors: Seidler Gerald
Published: September 2022

Zehn Jahre nach Einführung des Begriffs Industrie 4.0 findet die Digitalisierung weiterhin Einzug in die die Unternehmenswelt. Die Entwicklung automatischer Routenplanung und autonomer Fahrzeuge ist hierbei besonders im Bereich von Transport und Logistik relevant. Dieser Artikel beschäftigt sich mit den Enablern, Hürden und Auswirkungen von Industrie 4.0 in diesem Bereich.

Basierend auf einer im Vorfeld erfolgten Literaturrecherche, bei der fünfzehn mit Industrie 4.0 verbundene Themengebiete identifiziert worden waren, wurde eine Online- Umfrage durchgeführt, mit dem Ziel diese Themengebiete als Enabler, Hürden oder Auswirkungen von Industrie 4.0 im Hinblick auf Transport und Logistik zu kategorisieren.

Anhand einer quantitativen Analyse der 134 Rückmeldungen werden die wesentlichen Resultate, wie die Top-5 Enabler und Hürden, vorgestellt und die Relevanz von ökonomischen Einsparungspotentialen als wesentlicher Einflussfaktor präsentiert. Abschließend werden acht Hypothesen als Ausgangspunkt für weitere aufbauende Forschungsarbeiten abgeleitet.
A magyar lakosság utazási szokásai a COVID-19 első hulláma előtt és után
Authors: Hoschek Mónika , Németh Nikoletta , Mészáros Katalin
Published: September 2022

A turizmus Magyarországon 2019-ben csúcseredményeket ért el. A KSH adatbázisa alapján a kereskedelmi szálláshelyeken a vendégek száma 12,8 millió, a vendégéjszakák száma 31,3 millió volt. A belföldi turisták 15,6 millió, a külföldi turisták 15,7 millió vendégéjszakát töltöttek el Magyarországon. A COVID-19 világjárvány gyors terjedésének következtében 2020 márciusában Magyarország lezárta a határait, mely a külföldi és belföldi turizmust egyaránt jelentősen érintette. Az utazási korlátozások feloldásával 2020 nyarán robbanásszerűen megnövekedett elsősorban a belföldi utazások száma. Kutatásunkban a magyar fogyasztók üdülési, nyaralási preferenciáit hasonlítjuk össze 2019-ben és 2020-ban, mely lehetőséget nyújt arra, hogy összevessük a COVID-19 előtti és az első hullám utáni utazási szokások.
A szervezeti minőség javítása a hatékony működés szolgálatában – különös tekintettel a felsőoktatásra
Authors: Lakatos Péter Levente
Published: September 2022

A jelen írás a minőségbiztosítást, mint a szervezetfejlesztés hatékony eszközét veszi górcső alá. Áttekinti a minőségügy elméleti alapjait, történetét, kiemelve néhány úttörő szerzőt, gondolkodót. Az amerikai, eleinte főként az iparban alkalmazott elméleti megalapozás ismertetése után közelít az európai modellek, minőségelméleti megközelítések felé érintve részletesebben a TQM, ISO és EFQM rendszereket, ezt követően áttér a kritikai megközelítésekre, különös tekintettel a minőségbiztosítás oktatásban, felsőoktatásban való alkalmazhatósága, hatékonysága tekintetében. A tanulmány második felében kifejezetten a felsőoktatási minőségbiztosításra, különösen annak európai standardjaira koncentrál, a nemzetöziesedés oldaláról megközelítve azt. Kitér ennek keretében az agyelszívás, a digitális kampusz, az érintettek bevonása és a hallgatócentrikusság kérdéseire. Mindezek nyomán megállapítja, hogy a minőségbiztosítás a felsőoktatásban nem csak elkerülhetetlen, de szükséges folyamat, ami a szervezetfejlesztés leghatékonyabb eszköze is lehet egyben.
Diversity of SME Sizing Policies and Delimitations in the World
Authors: Pankotay Fruzsina Magda
Published: September 2022

Global partnerships are essential in order to maintain European competitiveness. People tend to think of Small and Medium Enterprises (SMEs) on a global scale, however we should always consider the following questions: Is this the right way? Are we aware of the current situation of SMEs in the world? The aim of the study is to demonstrate the characteristics and the roles of SMEs on national, on European and on global scales, based on secondary data collection in 21 countries, including Arab, Latin America, Asia and the European Union. Based on the differences and identities, the definitions of the various practices regarding sizing policies of SMEs and delimitations in the European Union and Hungary have been summarized, highlighting the “Made in Germany” model as a characteristic difference. In addition, the different data for the countries in a table by regions will also be summarizes. A micro-enterprise typically has less than 10 employees, but distinguishes between self-employment, family, craft and “existential work”. The diversity of size delimitation and the intention to unify are the result of globalization. In the age of Info Communication Technology (ICT) companies have a legitimate need to connect to the global supply chain, therefore gaining know­ledge of their potential partners. The goal is to see how SMEs can be compared on a global scale, outside the national and European Union frameworks. White looking for a global definition and size limitation of SMEs, I arrived to the global International Financial Reporting Standards (IFRS), more precisely to “IFRS for SMEs”, as a potentially usable benchmark for SMEs in the 21st century.
Digital Marketing: A Practical Approach
Authors: Nyikos Bendegúz Richárd
Published: September 2022

Charlesworth, A. (2018): Digital Marketing: A Practical Approach. Published February 6, 2018 by Routledge, ISBN 9781138039568
Admission of Guilt as a Basis for Concluding Procedural Agreements Using the BRICS Countries as an Example: A Comparative Legal Interpretation
Authors: Moskovskikh D.
Published: September 2022

The main focus of this article is to examine in greater depth the content of the admission of guilt, the issue of agreements with an investigation, and the criteria for the admissibility of confessions, using examples from not only the countries with Anglo-American and continental legal systems, but also taking into account the analysis of the legislation of the BRICS countries. Of particular interest are the attitudes of legislators from different countries towards this legal category, depending on their philosophical views, the political and economic environment, as well as the assessment of their readiness to move forward with the promises of humanization of legislation. The topic of guilty pleas in domestic criminal proceedings is not new for researchers and law enforcement officers. Legal scientists have identified both the advantages and the disadvantages of the forms based on this legal category. However, a gradual rejection of confessions as evidence is noticeable, and in the majority of cases, agreement with the prosecution plays a significant role. Despite the fact that confessions are officially no longer considered “the main thing,” in practice we are faced with the fact that, in fact, they are given priority over other forms of evidence. This duality creates uncertainty in scientific circles. We believe that this article can have a positive impact on the process of reforming certain provisions of criminal procedure law regulating procedural components, with mandatory compliance with the rights of participants in legal proceedings guaranteed by the basic laws of the country. To achieve the goal, we used the general scientific dialectical-materialistic method of cognition, as well as the following private scientific methods: logical-legal, comparative-historical, systemstructural. Both judicial practice and scientific research are analyzed in depth.
Mediação da informação e ação comunicativa Habermasiana
Authors: Fidelis Marli Batista , Gomes Henriette Ferreira
Published: September 2022

Reflete sobre o potencial da mediação da informação como via de fortalecimento para o mundo social da vida ante ao processo colonizador do mundo dos sistemas, considerando as atuais demandas sociais em âmbito informacional. A Ciência da Informação é cada vez mais convidada a encontrar caminhos para refletir sobre seu objeto como motor do desenvolvimento cultural e fortalecimento do mundo social da vida, de maneira a reafirmar seu lugar enquanto ciência social. Desse modo, a mediação da informação, estando presente em todas as ações do ciclo informacional, constitui-se base sustentadora de ações que contribuem para que a Ciência da Informação cumpra com sua missão e responsabilidade sociais ante as ambivalências da sociedade. Assim, a teoria da ação comunicativa de Jürgen Habermas pode nos proporcionar um diálogo possível com as abordagens teóricas da mediação da informação, no sentido de encontrar pontos que convergem para eixos integradores do mundo social da vida. Nesse sentido, entende-se que o trabalho com a informação demanda pesquisadores e mediadores conscientes que, no âmbito da Ciência da Informação, desenvolvam e tomem como referência estudos da mediação da informação que envolvam esferas apontadas por Habermas como espaços em estado de vulnerabilidade.
Quick and concise land boundary mapping using a drone at Villa Buccu, Kerobokan, Badung, Bali
Authors: Yasada Gede , Sutapa Ketut , Setyono Evin Yudhi
Published: September 2022

The effective measurement and mapping of the land is retrieval of accurate data according to position, in accordance with mapping provisions and efficient in both cost and time. One way that data can be retrieved effectively and efficiently is by using a drone, commonly called an unmanned aerial vehicle (UAV).Drone is a vehicle equipped with a wave control system, precision navigation (Global Positioning System/GPS) and flight control electronics so that it is able to fly according to flight planning (autopilot). This drone makes it possible to track the position and orientation of sensors implemented in local or global coordinate systems.  With the drone itself, it saves time because it can have an image of an area. Premark / Ground Control Point (GCP) is a point that is commonly used to improve measurement accuracy in mapping using drones, in this case using the Global Positioning System (GPS) Geodetic / RTK Hi Target tool. Mapping Using Drones was then used by many people, including for the purposes of villa spatial planning, so to support this activity a land boundary mapping was carried out at Villa Buccu, Kerobokan, Badung Bali.
Efecto de diferentes concentraciones de Albúmina Sérica Bovina en la congelabilidad del semen caprino
Authors: Martínez-Duran Josefa , Duverger-Tellez Omar , Díaz-Martínez Namibia , Interian-Alvarez Lisbani , Denis-García Ramón , Palacios-Espinosa Alejandro
Published: September 2022

Objective. Evaluate the effect of Bovine Serum Albumin (BSA) concentration on the freezability of goat semen in a Tris-based lyophilized preservative-diluter, without performing seminal washing, compared with a control preservative-diluter of lactose-skimmed milk (DC), removing the seminal plasma by centrifugation. Materials and methods. It will cover 90 ejaculates, volume, motility, concentration, viability, and sperm morphology. The fit ejaculates were mixed and the pool divided into five portions, each receiving one of 4 lyophilized combinations based on Tris-Glucose-Ac. Citrus and Glycerol with different concentrations of BSA (0.1%, 0.5%, 1% and 2%) or DC. It was frozen in 0.1 ml pellets in nitrogen vapors, and after 2 min., They were stored in liquid nitrogen until thawing 7 days later, the following were determined: motility percentage (30, 120 and 240 minutes), viability, damaged acrosomes and total anomalies (30 and 120 minutes) and were compared using a Binary Logistic Regression model. Results. The highest sperm motility and viability (p <0.05) in the three times was for 0.5%, 1% and 2% of BSA, which were higher than 0.1% of BSA and DC. Damages acrosome and total abnormalities at 30 and 120 minutes were lower (p <0.05) for 0.5%, 1% and 2% of BSA compared to 0.1% and DC. Conclusion. The cryopreservation of goat semen does not require seminal washing by centrifugation if 0.5-2% BSA is used as a membrane protector in a lyophilized dilute-conservative based on Tris-Glucose-Citric Acid and Glycerol.
Escala diagnóstica adaptativa operacionalizada de autorrelato (EDAO-AR): Evidências de validade
Authors: Yoshida Elisa Medici Pizão , Baptista Makilim Nunes , Argimon Irani Iracema De Lima
Published: September 2022

OBJETIVO: obter evidências de validade baseada na relação com outras variáveis da segunda versão da Escala Diagnóstica Adaptativa Operacionalizada de Autorrelato (EDAO-AR). METODO: As outras medidas foram obtidas com a Escala Baptista de Depressão - Versão Adulto (EBADEP-A) e Inventário de Depressão de Beck-II (BDI-II), além do critério de autorrelato de diagnóstico anterior de depressão. A amostra foi composta de 92 estudantes, maioria do sexo feminino e idade média de 23,8 (DP=7,6) anos. RESULTADOS: Houve predomínio de adaptação eficaz, sem sintomas depressivos, para ambos os sexos. A EDAO foi discriminativa para os participantes separados em dois grupos de sintomatologia depressiva. A EDAO-AR também correlacionou-se negativa e significativamente com a EBADEP-A e BDI-II e esses correlacionaram-se positivamente entre si. CONCLUSÕES: Os resultados foram interpretados como evidências de validade externa para a EDAO-AR. Limites da pesquisa são apontados.
Enhanced Technique for Multiple Face Detection Based on LBPH (Local Binary Patterns Histograms): A Review
Authors: Kumar Arvind , Shukla Puneet
Published: September 2022

Abstract: Facial recognition has long been an active study area because of its lack of modelling requirements and the wide range of applications. Because of this, daily tasks are increasingly being completed electronically rather than with pen and paper. Currently, computer vision is a broad topic that deals with complex programming by using input images and videos to carry out automatic tasks including detection, recognition, and classification. Face recognition and its applications have recently been regarded as one of the most successful image analysis applications, especially over the past few years. Even deep learning approaches, they are superior to the typical human visual system. Face Recognition is a special technology that uses distinctive facial traits to identify or confirm a person
Clinico-angiographic profiles and in-hospital outcomes of non-ST segment elevation myocardial infarction in Kurdistan Region of Iraq
Authors: Mohammad Ameen M , Issa Haval A , Saeed Saad Y
Published: September 2022

Objectives: This work aimed to study the clinical, angiographic profiles and in-hospital outcomes of NSTEMI cases in Duhok, Iraq.

Methods: This prospective study involved 283 patients with NSTEMI who were admitted to Azadi teaching hospital/Azadi heart center in Duhok, Kurdistan region of Iraq, between 2021 and 2022. The patient's demographic variables, major cardiovascular risk factors (smoking, hypertension, diabetes mellitus, hyperlipidemia and family history of coronary artery disease), clinical presentation, past history of myocardial infarction/ previous percutaneous coronary intervention (PCI) and drug history were collected. The GRACE risk score was calculated for each patient. Patients were followed up regarding the management strategies (whether conservative or invasive approach), and in-hospital complications and outcomes.

Results: The mean GRACE score was 142±26. 70% of cases underwent coronary angiography/ angioplasty, with a mean time to the coronary intervention of 8 days. 17% of the sample had developed different cardiovascular complications, with heart failure being the most common. The mortality rate was 7.4%.

Conclusion: The study demonstrated higher complications and mortality rates, especially among patients with higher GRACE scores, compared to rates found in most available studies, particularly in western countries. This finding could be secondary to a suboptimal coronary intervention for NSTEMI in terms of time to intervention and the proportion of patients who underwent it.
Intención emprendedora en estudiantes de la Universidad Pontificia Bolivariana: exploración de un modelo basado en la teoría del comportamiento planeado
Authors: Sarmiento-Suárez Jaime Enrique , Reyes-Rodríguez Juan Felipe , Ramírez-Montañez Julio César
Published: September 2022

El propósito del presente artículo fue, mediante un estudio de caso, caracterizar la intención de creación de empresas de los estudiantes de la Universidad Pontificia Bolivariana (UPB) de diferentes sedes (Montería, Palmira, Medellín y Bucaramanga), con el fin de definir estrategias que ayuden a consolidar y fortalecer la ruta de formación, los programas y contenidos académicos y el acompañamiento institucional orientado a la promoción del emprendimiento. Como referente teórico base se partió de la teoría del comportamiento planeado (TCP), en la cual la intención de un comportamiento de interés, como es el emprendedor, está determinada por las actitudes hacia la creación de empresa, las normas subjetivas y el control comportamental percibido.  El análisis empírico del estudio se realizó a partir de un enfoque cuantitativo basado en datos de un cuestionario en línea proporcionado a los estudiantes de pregrado de las cuatro sedes de la institución anteriormente mencionadas. A partir de una muestra de 4214 estudiantes matriculados en los distintos programas de estudio, se llevó a cabo un análisis de factores para establecer la estructura de las variables principales del modelo teórico y, adicionalmente, se exploraron otros constructos, tales como oportunidades y recursos del entorno, así como las desventajas y ventajas del emprendimiento. El análisis inferencial incluyó la regresión lineal múltiple para determinar la influencia de los antecedentes de la intención emprendedora y el análisis de varianza para examinar las diferencias entre los distintos constructos con base en grupos de informantes a partir de sus características sociodemográficas. Los resultados validaron la influencia de los tres antecedentes principales de la intención emprendedora de acuerdo con la TCP, así como también la presencia de familiares emprendedores, en particular que el padre sea socio o dueño de empresa. Adicionalmente, la intención emprendedora es influenciada por las oportunidades del entorno y las ventajas del emprendimiento percibidas por los individuos.
Viviendas con Electricidad Neutral con un Caso de Estudio en el Área Metropolitana de Bogotá-Colombia
Authors: Quintero-Pulido Diego Fernando , Castañeda-Ibáñez Nolly Nataly , Balda-Ayala Roberto Rafael
Published: September 2022

Este artículo revisa el desarrollo actual para incrementar el acceso a la electricidad y la implementación de viviendas con electricidad neutral (viviendas autónomas no conectadas a la red eléctrica) en diferentes escenarios. Además, se presentan con más detalle las posibles direcciones de investigación para tecnologías de viviendas con electricidad neutral. Para esto, se describe un caso de una posible vivienda con electricidad neutral en Colombia junto con algunos resultados iniciales de simulaciones usando energía solar fotovoltaica, una nueva batería a base de sal marina (the Sea-Salt battery) y una celda de combustible a base de glicerol (the Glycerol Fuel Cell) como sistema de respaldo. Las simulaciones utilizan el software BEopt y DstorageS. Este análisis se realiza utilizando datos medidos de consumo de electricidad en una vivienda localizada en la zona metropolitana de Bogotá-Colombia. Resultados preliminares muestran que una vivienda en Colombia puede funcionar con electricidad neutral, al tener una energía solar FV de 4 kW con una batería de sal marina de 10 kWh y una celda de combustible de glicerol de 2 kW funcionando de forma autónoma durante todo el año 2019.
Governance and strategies of gambling business in Southeast Asia
Authors: Rattaphong Sonsuphap
Published: September 2022

Numerous nations are worried about adolescent gambling addiction and challenges associated with gambling. Therefore, they have developed strategies to address these concerns (Dixon et al., 2016). This study aims to evaluate gambling management structures in Singapore, Hong Kong, Macau, and Thailand, and to compare educational-based gambling prevention strategies established in Singapore, Hong Kong, and Macau to find the best successful strategy for Thai students. For data collection, qualitative techniques such as document analysis and in-depth interviews were employed. The results indicate that the success of gambling management in Singapore, Hong Kong, and Macau is attributable to the collaboration of many sectors and the allocation of sufficient budgets. Gambling concerns are controlled completely by the government in Thailand, yet there are no government entities specifically responsible for gambling issues, creating management complications. In addition, a lack of finances may lead to poor management planning. The aforementioned three nations have achieved success in preventing gambling by employing strong national programmes and strategies. The objective of these programmes is to assist at-risk students in overcoming or preparing for addiction issues. Thailand must prioritise education on gambling, financial literacy, and collaboration of all relevant agencies to achieve success in gambling management and prevention.