bluuebunny/crossref_metadata_2025 huggingface dataset:
Temperature dynamics of carbonization of cotton fibers by microwave radiation in air
Authors:   Research Institute of Advanced Materials and Technologies, Matveev E. V. , Gajdar A. I. ,   Research Institute of Advanced Materials and Technologies, Lapshinov B. A. ,   Research Institute of Advanced Materials and Technologies, Mamontov A. V. ,   Research Institute of Advanced Materials and Technologies, Berestov V. V. ,   Research Institute of Advanced Materials and Technologies
Published: November 2022

Spectral pyrometry was used to determine the dynamics of microwave heating in air of samples (3 g samples) of cotton fibers pretreated with 2, 5, 7, and 10 % aqueous H3PO4 solution. Microwave heating was carried out in an open quartz reactor. The processing of the recorded radiation spectra and the calculation of the temperature were carried out using the “Spectral pyrometry” program. It has been established that the graph of the change in the temperature of the sample during heating has three characteristic regions — low-temperature, the region of unstable temperature, and the region of temperature stabilization. In the low-temperature region, free moisture is removed from the sample. The region of unstable temperature is associated with the process of cellulose combustion, which begins after the end of moisture evaporation at a temperature above 600 K. Under the influence of microwave radiation, all chemical processes intensify in the sample. Video filming during microwave heating showed that in the process of irradiation, sinuous slit-like cavities are formed on the surface of the sample, inside which electrical discharges and ignitions form “hot spots”, from which heat spreads to the entire volume of the sample and additionally heats it, which leads to significant temperature fluctuations. The combustion process continues until all the material is carbonized. After that, a relative stabilization of the temperature occurs, the value of which lies in the range of 1000 – 1200 K. It has been established that the higher the concentration of the H3PO4 solution used for pretreatment of the samples, the lower their temperature in the given area. It has been shown that the carbonization process begins in 70 – 75 s from the start of heating in the local areas of the sample. The results of comparative studies of the structure and elemental composition of samples before and after microwave exposure are presented. It is shown that after 180 s of heating, the fibers become significantly thinner, while maintaining integrity along the length. Carbonized fibers contain a significant amount of phosphorus, the concentration of which is maximum in the outer layers of the sample and is 15 – 20 %. The total weight loss of the samples depends on the concentration of the H3PO4 solution used to pre-impregnate the samples and ranges from 94 % for 2 % H3PO4 to 82 % for 10 % H3PO4.
THE HEALING EFFECT OF WATER ON WOMEN'S HEALTH FROM PAST TO PRESENT
Authors: YILDIRIM Dicle Filiz , SERÇEKUŞ Pınar , ÖZKAN Sevgi
Published: November 2022

In addition to the new treatment methods brought by technology, water is an important complementary treatment method that has been used from the past to the present. The purpose of this review is to examine the curative effects of water as a complementary treatment on women's health. Hydrotherapy applied during pregnancy reduces anxiety, stress, fatigue and edema, and increases the quality of life. Studies have shown that the use of water in the early stages of labor is effective in reducing labor pain, reduces the use of analgesia, and shortens the delivery time. Water in childbirth reduces anxiety, positively affects women to feel more comfortable and provide more birth control. Hydrotherapy is a method frequently used in the control of premenstrual syndrome from past to present, and it has been shown to be effective in alleviating premenstrual syndrome. It should not be forgotten that all water therapies should be used under the control of trained health professionals and in accordance with recommended protocols in order to be beneficial.
Pengujian Kualitatif Aplikasi Informasi Gempa Bumi dalam Bentuk Suara untuk Tunanetra
Authors: Supriyanto Joko , Fadlil Abdul , Sunardi Sunardi
Published: November 2022

Indonesia memiliki potensi gempa bumi yang cukup besar karena dilalui tiga lempeng aktif, yaitu lempeng Indo-Australia, Eurasia, dan Pasifik. Permasalahannya penyandang tunanetra masih kesulitan mendapatkan informasi gempa bumi yang masih berupa teks sehingga perlu dibuat aplikasi untuk mengubah teks ke suara. Tujuan pengembangan aplikasi ini diharapkan penyandang tunanetra mudah mendapatkan informasi gempa bumi melalui suara. Metodologi pengembangan aplikasi untuk mengubah informasi gempa bumi dari teks ke suara menggunakan model Fountain dan aplikasi dikembangkan menggunakan dua cara. Cara pertama dengan melakukan perekaman suara dalam bentuk wav kemudian digabunggabungkan atau disebut dengan Text to Speech Concatenation Wave Recording. Cara kedua, menggunakan Speech Aplication Programing Interface yang merupakan aplikasi teks ke suara bawaanWindows. Selanjutnya kedua aplikasi di uji untuk melihat kejelasan suara yang dihasilkan. Hasil pengujian terhadap 15 siswa Madrasah Tsanawiyah Yayasan Kesejahteraan Tuna Netra Islam menggunakan metode kualitatif didapatkan kejelasan suara yang dihasilkan dengan Concatenation Wave Recording mencapai 91,11% atau ada 13 siswa mendengar dengan jelas, sedangkan menggunakan Speech Aplication Programing Interface mencapai 95,56% atau 14 siswa mendengar dengan jelas.
Mobile Forensic of Vaccine Hoaxes on Signal Messenger using DFRWS Framework
Authors: Riadi Imam , Herman Herman , Siregar Nur Hamida
Published: November 2022

The COVID-19 pandemic is one of the factors that has increased the use of social media. One of the negative impacts of using social media is the occurrence of cybercrime. The possibility of cybercrime can also happen on one of the social media platforms, such as the Signal Messenger application. In the investigation process, law enforcement needs mobile forensic methods and appropriate forensic tools so that the digital evidence found on the perpetrator's smartphone can be accepted by the court. This research aims to get digital evidence from cases of spreading the COVID-19 vaccine hoaxes. The method used in this research is a mobile forensics method based on the Digital Forensic Research Workshop (DFRWS) framework. The DFRWS framework consists of identification, preservation, collection, examination, analysis, and preservation. The results showed that the MOBILedit tool could reveal digital evidence in the form of application information and contact information with a performance value of 22.22%. Meanwhile, Magnet AXIOM cannot reveal digital evidence at all. The research results were obtained following the expected research objectives.
Dampak SMOTE terhadap Kinerja Random Forest Classifier berdasarkan Data Tidak seimbang
Authors: Erlin Erlin , Desnelita Yenny , Nasution Nurliana , Suryati Laili , Zoromi Fransiskus
Published: November 2022

Dalam aplikasi machine learning sangat umum ditemukan kumpulan data dalam berbagai tingkat ketidakseimbangan mulai dari ketidakseimbangan kecil, sedang sampai ekstrim. Sebagian besar model machine learning yang dilatih pada data tidak seimbang akan memiliki bias dengan memberikan tingkat akurasi yang tinggi pada kelas mayoritas dan sebaliknya rendah pada kelas minoritas. Tujuan penelitian ini adalah untuk mengevaluasi dampak dari SMOTE (Synthetic Minority Oversampling Technique) pada pengklasifikasi Random Forest untuk memprediksi penyakit jantung. Data berjumlah 299 berasal dari UCI Machine learning Repository digunakan untuk membangun model prediksi berdasarkan 12 variabel independen dan 1 variabel dependen. Kelas minoritas dalam dataset pelatihan di oversampling menggunakan teknik SMOTE (Synthetic Minority Oversampling Technique). Model dievaluasi tidak hanya menggunakan ukuran kinerja Accuracy dan Precision saja, namun juga menggunakan alternatif ukuran kinerja lainnya seperti Sensitivity, F1-score, Specificity, G-Mean dan Youdens Index yang lebih baik digunakan untuk data yang tidak seimbang. Hasil penelitian menunjukkan bahwa teknik SMOTE (Synthetic Minority Oversampling Technique) mampu mengurangi overfitting sekaligus meningkatkan kinerja model Random Forest pada semua indikator. Peningkatan skor Accuracy sebesar 3.45%, Precision 4.8%, Sensitivity 7.1%, F1-score 4.8%, Specificity 2.1%, G-Mean 4.4%, dan Youdens Index 6.3%. Penelitian ini membuktikan bahwa dalam menentukan pengklasifikasi dengan algoritma machine learning seperti Random Forest, kemiringan kelas dalam data perlu diperhitungkan dan diseimbangkan untuk hasil kinerja yang lebih baik.
Development of OnlineWeb-Based New Student Graduation Application in Junior High School
Authors: Weriza Jusmita , Husein Ismail , Noranizamardia Noranizamardia , Fakhariza M , Marzuki Khairan
Published: November 2022

The student graduation information system is integral to managing and carrying out school information system activities. Especially in Junior High Schools (SMP) today, many still have not used a website-based information system due to the new internet network entering this area. In meeting the admin’s need, in particular, to deal with the problem of passing the distribution of receiving information or announcements, documentation of activities, teaching materials, and registration of new student participants have not run optimally as expected. In the system development method in this research, the author uses the System Development Life Cycle (SDLC) with the Waterfall model approach, which consists of 5 stages: analysis, design, implementation, testing, and implementation. The system design tool uses the UML (Unified Modeling Language) method using use-case diagrams according to system requirements. In developing the SDLC method in this study, the authors used it until the design stage. The results obtained from this research are a Web-based application system for new students’ graduation. With this tool, several related files will be generated. This new system can improve the quality of further student admissions, graduation information and school information through the website.
“Underprepared” Principals Leading Curriculum Reform in Lesotho
Authors: RALEBESE Moeketsı Davıd , JITA Loyiso , CHIMBI Godsend
Published: November 2022

This qualitative study explores the views of six Lesotho primary school principals regarding the in-service training they received to implement the integrated curriculum. Purposive sampling was used to select participants who met the inclusion criteria in Maseru, the capital city of Lesotho. A document analysis of the integrated curriculum was conducted, and open-ended interviews were audio-taped, coded, and analysed using the thematic interpretive approach. Findings show that the participants were partially trained to lead the implementation of the new integrated curriculum. The participants reported that their training was shorter compared to that of the teachers. Furthermore, teachers were trained before the principals, compelling the principals to rely on the teachers for implementation information and strategies. The unique finding emerging from the current study is that principals in Lesotho had to learn the dynamics of implementing the new integrated curriculum from the teachers they were supervising. We conclude that having insufficient knowledge about curriculum reform disempowers school principals and holds potential threats to the implementation of new curriculum initiatives, not only in Lesotho but in many other centralised education systems. We recommend that policy reformers and curriculum supervisory authorities should adopt a renewed approach to empower principals with appropriate curriculum reform leadership skills.
Fungsi Bahasa pada Konten Khotbah Pengkhotbah di Jemaat-Jemaat Lingkungan Kota Klasis Sentani
Authors: Wenda Daniel , Kabanga Lewi , Labobar Maryo Welly
Published: November 2022

We use language functions in various situations to achieve our purposes and meanings. Papuan Christianity life in the city, especially in GKI who live in Sentani, is educated by preachers’ sermons. This study aims to determine the language functions used by preachers in GKI churches in Sentani and their relations to the local education of Papua. This study used a qualitative method. The technique used to collect data was recording 12 samples in 4 weeks. The data was transcribed and reduced, and after that, indexed into the table as displayed data. The data was analysed based on the distribution of micro functions introduced by Leech. Firstly, the data was percentage to examine the dominance of language functions and then analysed by considering the phenomenon embodied. The results of this study reveal that the dominant language functions in preachers’ sermons are (1) informative, which consists of giving advice, lecturing, suggesting, and announcing; (2) the aesthetic function is signed with local language style and code-mixing/switching; (3) the expressive function demands the congregations’ attitude that indicates positive expression; (4) directive function is formed by request; (5) phatic function is constructed in the forms of contextual greetings, namely spirituality and local greeting of Papua.
Semiotika Nonverbal dalam Musik Video “Azza” Karya Rhoma Irama (Kajian Semiotika Roland Barthes)
Authors: Amalia Anindita Fikri , Kristanto Nurdien Harry , Waluyo Sukarjo
Published: November 2022

This study aims to describe non-verbal semiotics and its relation to Roland Barthes' semiotics, namely connotation and denotation. This research with the object of the study of the music video "Azza" by Rhoma Irama uses qualitative research methods to find non-verbal semiotics contained in the object of study. The results of this study, namely in the music video "Azza" by Rhoma Irama, there are seven body signs, namely (a) signals; (b) facial expressions; (c) eye contact; (d) body language; (e) touch; (f) cue; and (g) dance. It is also related to Roland Bathes' semiotics. Signs expressed in the music video have connotative and denotative meanings that the singer wants to convey through his music and videos. The connotative meaning in the music video "Azza", sung by Rhoma Irama, can be seen in the scenes glorifying God's power.
Hubungan Kekerabatan Bahasa Aceh, Bahasa Devayan, Bahasa Sigulai, dan Bahasa Jamee
Authors: Muhammad Sitti Rahmah , Hendrokumoro Hendrokumoro
Published: November 2022

This study investigates the percentage of kinship level, separation time, and phonemic correspondence among Acehnese, Devayan, Sigulai, and Jamee languages by applying theories from Keraf (1996) and Crowley & Bowern (2010). Data was collected using interviewing, recording, listening, and note-taking techniques. Data analysis applied lexicostatistics and glottochronology techniques. The study's results indicated that Acehnese, Devayan, Sigulai, and Jamee languages were related. Based on the results of lexicostatistical calculations, it is known that the Acehnese-Devayan language, Acehnese-Jamee language, Devayan-Sigulai language, Devayan-Jamee language, and Sigulai-Jamee language can be grouped into (family) while Acehnese-Sigulai language is at the (stock) level. Acehnese and Devayan languages were a single language estimated between 2,054-2,458 years ago. Acehnese and Sigulai languages were a single language around 3,169-3,420 years ago, Acehnese and Jamee languages were a single language in 1,836 -2,206 years ago, Devayan and Sigulai languages were a single language in 1945 -2283 years ago, Devayan and Jamee were a single language in 2114-2,316 years ago, Sigulai and Jamee were a single language between 2,010-2.404 years ago. In addition, phonemic correspondences were also found within the four languages.
Mendiskusikan Definisi Sastra Islam dan Sastra Islami dalam Kesusastraan Indonesia Masa Kini
Authors: Azhari Dian Rizky , Yoesoef M. , Setyani Turita Indah
Published: November 2022

The use of the terminology of Islam Literature and Islamic Literature by literary academics and readers in Indonesia is still confusing. It is inseparable from the development of Islam in Indonesia after the New Order. At that time, publishers had a unilateral claim that their work was the work of Islam literature or Islamic literature. Based on that, this study aims to find the definition and characteristics of the terminology of Islam Literature and Islamic Literature. This study uses the dialectical method, which is a method that contrasts several different views on a problem, in this case, the definition of Islam Literature and Islamic Literature. To collect data, this study uses a literature study of experts' opinions, literary observers, data on literary works, and the development of Indonesian literature. The results of the discussion show that Islam literature refers to all literary works that are strictly based on the text of the holy book and hadith; while Islamic literature can be more fluid than Islamic literature, it does not have to be based on scriptures and hadith, but the values ​​contained in it must be still based on Islamic teachings.
Rebranding Produk Kopi Excelsa Oleh Kelompok Masyarakat KOPI GUNUNG Dengan Packaging Baru dan Digital Marketing
Authors: Achmad Zainal Abidin , Wuryandari Yenny , Mas’udah Kusuma Wardhani , Tamrin M. Husni
Published: November 2022

Coffee is a leading commodity in Jombang Regency. One of these coffee varieties is Excelsa Coffee. The main obstacle for coffee farmers and traders in Sumberjo Village is the processing of excelsa coffee which is quite complicated. The Grant Program for Application of Research Results for the Community (PIHAT) aims to foster community groups KOPI GUNUNG in Sumberjo Village, Wonosalam District, Jombang Regency to have knowledge and skills in coffee plant care and digital marketing. The results of the identification of the problem of Pokmas KOPI GUNUNG as a partner, the PIHAT team provides solutions in the form of a) Increasing knowledge and skills in caring for coffee plants, b) Improving the quality of new labels and packaging, c) Creating Instagram accounts and making marketing support profile videos, and d) Digital marketing training. After partners gain knowledge and skills in caring for coffee plants, knowledge of digital marketing skills, and producing coffee product packaging, the goal of implementing this PIHAT program is to increase sales of coffee products from the KOPI GUNUNG community group with the brand and packaging "Cakra Dewa." In addition to articles in community service journals, PIHAT's outputs are the Profile Video, news, and Instagram accounts. Kopi merupakan komoditas unggulan Kabupaten Jombang. Salah satu varietas kopi tersebut adalah Kopi Excelsa. Kendala utama bagi petani dan pedagang kopi di Desa Sumberjo adalah perawatan kopi excelsa yang cukup rumit. Program Hibah Penerapan Hasil Penelitian Bagi Masyarakat (PIHAT) bertujuan untuk membina kelompok masyarakat KOPI GUNUNG di Desa Sumberjo, Kecamatan Wonosalam, Kabupaten Jombang agar memiliki pengetahuan dan keterampilan dalam perawatan tanaman kopi dan pemasaran digital. Hasil identifikasi masalah Pokmas KOPI GUNUNG sebagai mitra, maka tim PIHAT memberikan solusi berupa: a) Meningkatkan pengetahuan dan keterampilan dalam merawat tanaman kopi, b) Meningkatkan kualitas label dan kemasan baru, c) Membuat akun Instagram dan membuat video profil penunjang pemasaran, dan d) Pelatihan pemasaran digital. Setelah mitra mendapatkan pengetahuan dan keterampilan dalam merawat tanaman kopi, pengetahuan keterampilan digital marketing, dan memproduksi kemasan produk kopi, maka sasaran akhir dari pelaksanaan program PIHAT ini adalah meningkatkan penjualan produk kopi dari kelompok masyarakat KOPI GUNUNG dengan brand dan kemasan “Cakra Dewa.” Selain artikel pada jurnal pengabdian kepada masyarakat, luaran PIHAT ini adalah Video Profil, Berita, dan akun Instagram.
Improving Competence in Vocational High Schools through Accounting and Taxation Training
Authors: Wati Yenny , Yusrizal Yusrizal , Suharti Suharti
Published: November 2022

Kegiatan pengabdian masyarakat ini dilakukan karena minimnya pengetahuan baru dalam pendidikan akuntansi dan perpajakan dari pihak sekolah. Kegiatan ini bertujuan untuk memberikan pelatihan guna meningkatkan kompetensi siswa di bidang akuntansi dan perpajakan. Metode yang digunakan dalam kegiatan ini adalah metode offline, metode ceramah dan pelatihan praktik, metode diskusi, dan penyebaran kuesioner untuk perbaikan kegiatan pengabdian ini kedepannya. Kegiatan ini akan berlangsung secara offline pada hari Jumat tanggal 23 September 2022. Peserta yang mengikuti kegiatan ini berasal dari kelas 12 jurusan akuntansi SMK Metta Maitreya Pekanbaru yang berjumlah 40 orang. Berdasarkan hasil evaluasi dari pemberian soal-soal akuntansi dan perpajakan, pengetahuan siswa meningkat sebesar 75%. Peningkatan ini terjadi karena para siswa mampu memperoleh pengetahuan dan pemahaman mengenai akuntansi dan perpajakan dengan cara yang berbeda dari yang diajarkan di sekolah. Evaluasi kegiatan pelatihan akuntansi dan perpajakan memberikan hasil yang memuaskan dan meninggalkan kesan positif bagi siswa SMK Metta Maitreya Pekanbaru. Kegiatan ini diharapkan dapat meningkatkan motivasi belajar siswa terhadap mata pelajaran akuntansi dan perpajakan. This community service activity was carried out due to the school's lack of new accounting and taxation education. This activity aims to provide students with training to improve their accounting and taxation skills. This activity employs the offline method, the lecture method and practical training, the discussion method, and the distribution of questionnaires to improve this service activity in the future. This activity will take place offline on Friday, September 23, 2022. This activity attracted 40 participants from the class 12 accounting department at SMK Metta Maitreya Pekanbaru. Students' knowledge increased by 75% based on the evaluation results of accounting and taxation questions. This rise is due to students gaining knowledge and understanding of accounting and taxation in ways other than what is taught in schools. The evaluation of accounting and taxation training activities produced satisfactory results and left a favorable impression on the students of SMK Metta Maitreya Pekanbaru. This activity is intended to increase students' interest in accounting and taxation subjects.
Strategi Pemasaran Ideal di Era Digital untuk Meningkatkan Penjualan Produk UMKM
Authors: Jatmiko Novi Satria
Published: November 2022

Strategi Pemasaran adalah salah satu cara memenangkan keunggulan bersaing yang berkesinambungan, baik itu untuk perusahaan yang memproduksi barang atau jasa. Perusahaan menentukan konsumen mana yang akan dipilih untuk dilayani, mengelompokkan pasar hingga bagaimana menentukan distribusi dan kegiatan promosinya. Di era ilmu dan teknologi yang semakin berkembang pesat saat ini, maka diperlukan teknik-teknik pemasaran yang mampu mengikuti perkembangan zaman. Strategi pemasaran yang baik sangat diperlukan oleh Usaha Mikro, Kecil, dan Menengah (UMKM). UMKM memliki peranan yang sangat strategis dalam pembangunan ekonomi nasional karena terbukti mampu bertahan dalam segala kondisi, baik di saat krisis moneter maupun pandemi. Namun demikian, bagaimana menentukan strategi pemasaran yang baik masih menjadi kendala utama bagi mereka. Tujuan kegiatan ini adalah untuk memberikan pengetahuan tentang strategi pemasaran secara offline dan online kepada masyarakat pelaku UMKM. Metode yang dilakukan adalah dengan cara seminar. Berdasarkan hasil survey yang dilakukan setelah pelaksanaan kepada 11 peserta yang mengikuti kegiatan ini maka didapatkan 9 orang (81%) menyatakan bahwa kegiatan ini sangat bermanfaat dan 2 orang (19%) menyatakan cukup bermanfaat maka dapat disimpulkan bahwa kegaiatan seminar strategi pemasaran ideal di era digital untuk meningkatkan penjulan produk sangat bermanfaat bagi para pelaku UMKM. Marketing Strategy is one way to win a sustainable competitive advantage, be it for a company that produces goods or services. The company determines which consumers to choose to serve, groups the market to how to determine its distribution and promotional activities. In the era of science and technology that is growing rapidly today, marketing techniques are needed that are able to keep up with the times. A good marketing strategy is needed by Micro, Small, and Medium Enterprises (MSMEs). MSMEs have a very strategic role in national economic development because they are proven to be able to survive in all conditions, both during the monetary crisis and pandemic. Nevertheless, how to determine a good marketing strategy is still the main obstacle for them. The purpose of this activity is to provide knowledge about offline and online marketing strategies to the community of MSME actors. The method carried out is by means of seminars. Based on the results of a survey conducted after the implementation of 11 participants who took part in this activity, 9 people (81%) stated that this activity was very useful and 2 people (19%) stated that it was quite useful, so it can be concluded that the ideal marketing strategy seminar activity in the digital era to increase product sales is very useful for MSME actors.
Определение степени включения циннаризина B липосомы из соевого лецитина
Authors: Полковникова Юлия Александровна
Published: November 2022

Разработана методика определения степени включения циннаризина в липосомы из соевого лецитина. Рассчитаны константы уравнений Фрейндлиха и Ленгмюра, позволяющие сделать вывод о связывании циннаризина с липосомами. Установлено эффективное связывание циннаризина с липосомами из соевого лецитина в кислой среде. Обработка липосом ультразвуком является целесообразной при добавлении циннаризина к сухой липидной плёнке, так как является фактором, повышающим биодоступность.
Новые палладийсодержащие полимерные катализаторы синтеза эналаприла
Authors: Абдуллаев Махрам Гасанович
Published: November 2022

Получены новые палладийсодержащие полимерные катализаторы гидрогенизационного аминирования этилового эфира 2-оксо-4-фенилбутановой кислоты дипептидом α-аланил-α-пролином. На основании полученных эмпирических данных предложена оптимальная усовершенствованная схема каталитического синтеза эналаприла в мягких условиях. Каталитические свойства новых, для данной реакции, полимерных палладийсодержащих катализаторов, сопоставлялись с классическими гетерогенными палладиевыми катализаторами гидрогенизации — Pd/C и Pd/CaCO3. Обнаружено, что новые палладийсодержащие полимерные катализаторы существенно превосходят по селективности и стабильности свои гетерогенные аналоги.
Положения национального и евразийского законодательства о фармакопее: актуализация и перспективы развития
Authors: Яруткин Алексей Викторович , Багирова Валерия Леонидовна
Published: November 2022

В статье приведены сведения об основных положениях нормативных правовых актов, устанавливающих правовые основы издания Государственной фармакопеи и Фармакопеи Евразийского экономического союза; проведён сравнительный анализ норм отечественного законодательства и актов Евразийского экономического союза с учётом подходов к изданию ведущих мировых фармакопей. На основании общемировой тенденции к гармонизации требований к качеству лекарственных средств отражены перспективные направления развития национального законодательства. Проведённые исследования показали необходимость уточнения понятийного аппарата, совершенствования структуры отечественной фармакопеи, систематизации и оптимизации установленных норм, а также введения новых требований для эффективного регулирования процесса разработки и поддержания в актуальном состоянии фармакопейных требований, а также повышения прозрачности процесса разработки фармакопейных требования для субъектов обращения лекарственных средств. Информационно-аналитический анализ выявил перспективные направления развития отечественного законодательства в области фармакопейных требований, широкое обсуждение которых позволит повысить эффективность работы по установлению на государственном уровне требований к качеству лекарственных средств и в дальнейшем внести изменения в существующие нормативные правовые акты и, при необходимости, разработать и утвердить новые подзаконные акты, детально и однозначно регулирующие данный процесс.
Saygı Odaklı Bir Bilim İnsanına Armağan - Prof. Dr. Ruşen Keleş’in Yaşamı, Bilimsel Portresi üzerine Bir İnceleme
Authors: KESKİN Mehmet
Published: November 2022

Prof. Dr. Ruşen Keleş 19 Ağustos 1932 yılında Trabzon’un Araklı ilçesinde dünyaya geldi. İlköğrenimini Trabzon’da, Cudi Bey İlkokulu’nda, ortaöğrenimini ise Kemerkaya Ortaokulu’nda tamamladı. Trabzon Lisesi’nden mezun olmasının ardından, Siyasal Bilgiler Fakültesi giriş sınavını kazanarak Mülkiye öğrencisi oldu. 1950–54 yıllarını kapsayan öğrencilik döneminde, SBF Öğrenci Derneği’nde genel kurul başkanlığı, yönetim kurulu üyeliği ve kültür kolu başkanlığı yaptı. Öte yandan Milli Türk Talebe Federasyonu altında, Cumhuriyetçi, Kemalist ve barışçıl öğrenci hareketleri içinde yer aldı. Merkezi İstanbul’da bulunan (alkollü içki karşıtı) Yeşilay Derneği’nin SBF ve Ankara’daki örgütlenme ve eğitim çalışmalarına, okul arkadaşı Cevat Geray ile birlikte öncülük etti. Prof. Keleş, Kentleşme bilimine kazandırdığı yüzlerce eserleri ile Türkiye’de Kentleşme, kent hukuku, kent bilim ve Yerel yönetimler konusunda çığır açmıştır. Prof. Keleş’in h-indeksi katsayısı 9, tüm yayınlar için aldığı atıf sayısı 1000’leri geçmiştir. 90. Yaşına girmek üzere olan bu saygı odağı bilim insanı Prof. Dr. Ruşen Keleş’in bilimsel geçmişi bağlamında birşeyler yazmanın güçlüğü bir yana bu alandaki çalışmaları bilimsel göstergeleri dikkate alan veri odaklı bu makalenin yararlı olacağı gerçeğiyle elde edilen detaylı özgeçmiş ve akademik veriler öne çıkmaktadır. Prof.Keleş’ in yıllardan beri yönettiği tez danışmanlıklarına ilişkin verilere YÖK Ulusal Tez Merkezi veri tabanından erişilmiştir. Çalışmada ulaşılan bulgulara göre, Prof. Keleş’in akademik üretimleri ve istatistikleri ile Kentleşme, kent hukuku,yerel yönetimler ve benzer disiplinler bağlamında yetişmekte olan akademisyenler ve araştırmacılar açısından pozitif rol model olduğu gerçeği aydınlatıcı ve önemli olmaktadır.
Nazmi Alacadağlı ile Ruşen Keleş Üzerine
Authors: ALACADAĞLI Nazmi
Published: November 2022

Bazı insanlarla aynı zaman diliminde, aynı ülkede, aynı şehirde ya da aynı mekanda yaşamak bazen insan için büyük bir şanstır. Ruşen Hocam benim için tanımaktan dolayı kendimi şanslı ve ayrıcalıklı hissettiğim bir insan. Her birlikteliğimizde, her sohbetimizde, yaşamıma bir şeyler katmaya, yaşam zenginliğimi ve farkındalığımı artırmaya devam eden (bence) bir üst insan.
Persatuan indinesia dalam kesehatan
Authors: Salma Adevia
Published: November 2022

ABSTRAKArtikel persatuan indonesia dalam kesehatan Sila Persatuan indonesia mengandung arti bersatunya macam-macam corak yang beraneka ragam menjadi satu kebulatan yang utuh dan serasi. Kesatuan adalah keEsaan, sifat tunggal atau keseutuhan. Tingkat kepatuhan masyarakat terhadap protokol kesehatan 5M secara konsisten terus meningkat secara nasional. Dengan skala 1-10, skor kepatuhan memakai masker meningkat dari 7,72 menjadi 7,88 di 20 Agustus hingga 3 September 2021. Skor kepatuhan menjaga jarak juga meningkat dari 7,53 menjadi 7,75 pada periode 20 Agustus-3 September 2021. Sedangkan skor kepatuhan mencuci tangan meningkat dari 7,64 menjadi 7,86 pada periode 20 Agustus - 3 September 2021. Kepatuhan ini terus di prioritaskan oleh pemerintah untuk menekan angka kejadian positif covid-19. Masyarakat menjadi komponen utama dalam menjalankan kepatuhan protokol kesehatan. protokol kesehatan ini dikenal dengan sebutan 5M. Protokol kesehatan 5M di terapkan untuk membantu pencegahan penularan virus Covid-19. Pembentukan protocol kesehatan ini berfungsi untuk menghindarkan masyarakat dari virus. Kata kunci : Persatuan dan kesatuan, Kepatuhan, Protokol Kesehatan
PERSATUAN DAN KESATUAN DALAM BERPERILAKU HIDUP BERSIH DAN SEHAT
Authors: FADILLA ASYAFA'A RIZQI
Published: November 2022

Persatuan merupakan suatu gabungan (ikatan dan kumpulan)dengan bagian yang sudah utuh bersatu,perserikatan dan serikat.Sementara kesatuan berarti perihal satu kesatuan,sifat,yang tunggal,dan kesatuan.Perilaku Hidup Bersih dan Sehat (PHBS) merupakan suatu perilaku dimana seseorang menerapkan perilaku kebersihan dalam kehidupan sehari-harinya dengan memperhatikan tingkat kesehatannya.Hidup sehat merupakan hal yang seharusnya diterpakan oleh setiap orang karena manfaat yang didapat sangat banyak,mulai dari kesehatan jiwa dan raga hingga kefokusan dalam mengerjakan sesuatu,serta pada kesejahteraan hidup anggota keluarga serta terciptanya suasana yang indah,asri serta damai sehingga membuat lingkungan hidup terasa nyaman.
Disruptive Strategy and Innovation Spotify Music
Authors: Yudhistira Muhammad Rizqi
Published: November 2022

Disruptif adalah inovasi yang membantu menciptakan hal baru dan tentunya pangsa pasar baru. Bahkan bisa dikatakan mengganggu dan merusak pasar yang sudah ada sebelumnya.Perusahaan yang akan saya bahas terkait dengan inovasinya di bidang music dan membuatpasar dari music konvensional terganggu adalah perusahaan Spotify. Spotify sendiri adalahsebuah platform layanan penyiaran music yang berbasis di Stockholm, Swedia yangdiluncurkan pada 2008 oleh Daniel Ek. Sebenarnya Spotify ini sendiri dikembangkan padatahun 2006 oleh mantan CTO dari Stardoll yaitu Daniel Ek. Spotify sendiri berasal dari kataSpot dan Identify. Sejak peluncurannya, Spotify berhasil menggeser berbagai musickonvensional dan merusak pangsa pasar dari bisnis music konvensional itu sendiri. Sebenarnyaawal dari music digital bukan pertama kali dicetuskan oleh Spotify namun oleh Napster.Napster sempat mencuri perhatian pada tahun 2000 namun mendapat banyak kecaman sertaboikot dari para produsen music konvensional.
Tugas pkn pak ali sodik
Authors: tamelan Susanti bebhe
Published: November 2022

Hak Asasi Manusia (HAM) adalah hak yang melekat pada diri setiap Manusia sejak awal dilahirkan yang berlaku seumur hidup dan tidak dapat Diganggu-gugat oleh siapapun. Setiap warga memiliki kewajiban untuk Menjunjung tinggi nilai hak asasi manusia tanpa membeda-bedakan status, Golongan, keturunan, jabatan dan lain sebagainya. Setiap hak akan dibatasi oleh Hak orang lain. Jika dalam melaksanakan hak, kita tidak memperhatikan hak Orang lain, maka yang terjadi adalah benturan hak atau kepentingan dalam hidup Bermasyarakat, berbangsa, dan bernegara.“Hak Asasi Manusia di Indonesia bersumber dan bermuara pada Pancasila, yang artinya Hak Asasi Manusia mendapat jaminan kuat dari falsafah bangsa, yakni Pancasila. Bermuara pada Pancasila dimaksudkan bahwa pelaksanaan hak asasi manusia tersebut harus memperhatikan garis-garis yang telah ditentukan dalam ketentuan falsafah Pancasila. Bagi bangsa Indonesia, melaksanakan hak asasi manusia bukan berarti melaksanakan dengan sebebas-bebasnya, melainkan harus memperhatikan ketentuan-ketentuan yang terkandung dalam pandangan hidup bangsa Indonesia, yaitu Pancasila. Hal ini disebabkan pada dasarnya memang tidak ada hak yang dapat dilaksanakan secara mutlak tanpa inganar Belakangmemperhatikan hak orang lain karena dapat melanggar hak asasi yang dimiliki oleh orang lain.
Inovasi Disrupsi dalam Kepraktisan Penggunaan Wikipedia mengalahkan Ensiklopedia Tradisional
Authors: nafisa safira audrey , Purnomo Agung
Published: November 2022

Pada era digital saat ini, segala seuatu menjadi lebih mudah dan praktis contohya dalam jika kita ingin menambah pengetahuan dan wawasan kita dapat mengangkses hal yang kita ingin tahu melalui ensiklopedia. Ensiklopedia sendiri merupakan bahan rujukan yang menyajikan informasi secara mendasar namun lengkap mengenai berbagai masalah dalam berbagai bidang atau cabang ilmu pengetahuan, di samping itu ada pula ensiklopedia yang hanya mencakup satu cabang ilmu pengetahuan. Jika pada jaman dulu kita memerlukan buku-buku untuk mengakses ensikopedia, kini kita dapat mengaksesnya kapan saja dimana saja melalui ensiklopedia online yang mudah diakses yaitu Wikipedia. Platfom ini membuat perusahaan ensiklopedia memiliki pesaing ketat bahkan mudah tergantikan. Hal ini dapat terjadi dikarenakan Wikipedia sangat mudah digunakan dan aksesnya sangat praktis.
Mengenal Inovasi Disrupsi pada Cross-platform Instant Messaging Apps: Studi Kasus Line
Authors: Margareta Maria
Published: November 2022

Inovasi disrupsi adalah bentuk upaya yang dilakukan oleh Line dengan menggunakan cara-cara baru dan berbeda dengan sebelumnya. Dimana inovasi disrusi ini telah membantu Line dalam mempertahankan eksistensi dan mengembangkan produknya dalam industri telekomunikasi. Hal ini dapat dibuktikan dari perkembangan Line sejak pertama kali diluncurkan pada 23 Juni 2011 hingga saat ini telah berhasil berinovasi dan menciptakan beberapa produk lintas industri dalam satu aplikasi, seperti Line Splitbill, Line Bank, Line Stickers, dsb.
ALGORITMO PARA CALCULAR LA RUTA MÁS SEGURA Y ÓPTIMA
Authors: Cano Sara , Tabares Samuel Andrés Areiza
Published: November 2022

En los últimos años, han aumentado los casos de acoso sexual y crímenes en las calles de Medellín. Por lo tanto, es fundamental enfrentar esta problemática desarrollando e implementando un algoritmo que encuentre el mejor camino entre dos puntos de la ciudad, disminuyendo la distancia a recorrer y buscando el trayecto más seguro, con el fin de disminuir la inseguridad callejera. En este proyecto se implementó el algoritmo de Dijkstra para calcular tres caminos tomando en cuenta la distancia en metros y el riego de acoso callejero. Esto es fundamental ya que en un camino es posible que sea menor la distancia, pero no el riesgo, mientras que en otro caso ocurre al contrario y finalmente en el camino restante ambas variables son optimizadas en igual medida. Este algoritmo tiene un tiempo de ejecución de 1 segundo en promedio y una complejidad de O((V+E) log|V|).
The Mediating Role of Income, Healthy Food Availability, and Consumption in Rural Health Disparities
Authors: Smith Benjamin James , Tomiyama A. Janet , Berkman Elliot , John Deborah , Mantell Bryan
Published: November 2022

Background. People in rural (vs. urban) places have worse health outcomes. We examined the role of healthy food availability and consumption in this health disparity. Method. We surveyed rural (n=313) and urban (n=458) Oregon residents online, and analyzed data from rural (n=1 235) and urban (n=13 912) respondents in the U.S. nationally representative Health Information National Trends Survey (HINTS). We followed up pre-registered simple mediation models with post-hoc multi-mediator models combining the datasets. Results. As pre-registered, healthy food availability mediated the rurality-BMI relationship in the Oregon survey (8% proportion mediated, 95% CI [2%, 48%], p<0.05). In HINTS, we found fruit and vegetable consumption mediated the relationships between rurality and self-rated health (ACME=0.03 [0.02, 0.04], p<0.001), high blood pressure (ACME=0.004 [0.002, 0.01], p<0.001), and metabolic health (0.008, [0.004, 0.01], p<0.001). In a hybrid model, the effect of rurality on BMI (ACME=0.0119 [0.0043, 0.0227], p=0.0292) and health outcomes (ACME=0.0029 [0.0011, 0.0054], p=0.0083) was mediated by a combination of income and perceived fruit and vegetable availability and consumption. Conclusion. Nationwide data demonstrate rural-urban disparities in cardiometabolic health, self-rated health, and BMI are mediated by a series of two factors: income, and fruit and vegetable consumption. Oregon data suggests those factors in turn are mediated by a third factor, fruit and vegetable availability, and overall, the three factors together appear to mediate the rural-urban disparities. To address rural-urban health disparities, individual health behaviors, household income, and community healthy food availability should be targeted together.
Habit, health, and socialising: New insights into diverse motives for consuming alcoholic and non-alcoholic drinks
Authors: Werner Johanna , Papies Esther K. , Best Maisy , Scheepers Christoph , Barsalou Lawrence
Published: November 2022

Previous research on motives for drinking has typically focused on alcoholic drinks, sugary drinks, or water, assessing consumption motives with direct assessment methods. Because drinking plays an important role in the long-term maintenance of health, a comprehensive assessment that examines a broad range of drinks and drinking motives could be informative and useful. To provide a comprehensive assessment, we developed and assessed a situated model of drinking behaviour that used drinking motives to indirectly predict the consumption frequency of both alcoholic and non-alcoholic drinks. We expected that predictive patterns of drinking motives would vary across drinks as well as across individuals. A UK sample (n = 900) completed an online assessment, evaluating 11 drinks on 34 potential motives. An exploratory factor analysis identified 7 motivational factors that we interpreted as habit, negative consequences, health/functionality, bitterness, sensory enjoyment, ease of regulation, and socialising/positive consequences. These factors explained considerable variance in self-reported drink consumption, both for individual drinks (median = 65%) and for individual participants (median = 95%). Only subtle differences emerged across the predictive patterns for individual drinks, whereas greater variability emerged across individual participants. The results show the value of comprehensively assessing a spectrum of drinking motives across alcoholic and non-alcoholic drinks.
Screening zur Einschätzung des psychosozialen Nachsorgebedarfs in der pädiatrischen Onkologie (NPO-11) für Selbst- und Elternbericht
Authors: Kulisch Leonard Konstantin , Herrmann Jessy , Herzog Kristina , Einsiedel Hagen Graf , Kamm-Thonwart Remo , Hoffmann Rahel , Jäschke Yvonne , Martini Julia , Schepper Florian
Published: November 2022

Hintergrund. Krebserkrankungen bei Kindern sind mit einem erhöhten Risiko für psychosoziale Belastungen assoziiert. Zur quantitativen und qualitativen Bedarfseinschätzung nach psychosozialer Nachsorge liegen bisher keine Instrumente vor. Mit dem NPO-11 wurde nun ein ökonomisches Screening entwickelt. Patienten und Methoden. Elf dichotome Items erfassen die Bereiche Progredienzangst, Traurigkeit, Antrieblosigkeit, Selbstwertprobleme, Schul- und Ausbildungsprobleme, somatische Beschwerden, emotionaler Rückzug, soziale Desintegration, Pseudoreife, Eltern-Kind-Konflikte sowie Elternpaar-Konflikte entweder im Selbst- oder Elternbericht. Zur psychometrischen Überprüfung wurde der NPO-11 an N=101 Eltern-Kind-Dyaden getestet.Ergebnisse. Selbst- und Elternberichtversion zeigten eine gute Ausfüllgüte mit Zustimmungsraten ohne Boden- oder Deckeneffekte. Die Interrater-Reliabilität der 11 Items war ausreichend bis moderat. Faktorenanalytisch konnte die Gültigkeit eines Gesamtwerts nachgewiesen werden. Dieser zeigte für Selbst- und Elternbericht eine ausreichende bzw. gute interne Konsistenz sowie hohe Validität durch Korrelationen mit gesundheitsbezogener Lebensqualität.Schlussfolgerung. Mit dem NPO-11 wurde ein reliables und valides Screening zur Einschätzung des psychosozialen Nachsorgebedarfs in der pädiatrischen Onkologie entwickelt. Bei dem Übergang von stationärer zu ambulanter Behandlung kann eingeschätzt werden, welches Ausmaß an psychosozialen Interventionen notwendig ist und auf welche Themenfelder diese Angebote ausgerichtet sein sollten.
A cross-sectional online survey on COVID19 related anxiety among students of Tertiary care center
Authors: Ganiger Fakirappa B , Bijjal Somashekhar , Gadad Aran V , Mugali Jitendra , Shaikh Manal , Iti Jannatbi
Published: November 2022

Background: COVID19 pandemic has deleterious effect on mental health of people around world. Like medical professionals, students of tertiary care center are also at higher risk of developing anxiety related to COVID19.
Objectives: To assess severity of COVID19 related anxiety and identify underlying risk factors among students of different courses of tertiary care center.
Materials and Methods: A cross-sectional online survey was conducted including 704 students aged above 18 years from different courses of tertiary care center. Study was conducted after obtaining clearance from Institutional Ethical Committee and informed consent was obtained online. Anxiety related to COVID19 was assessed using COVI19 Anxiety Syndrome Scale (COVID19ASS). Statistical analysis for descriptive data was done by using mean and percentage.
Results: Study comprised of 50.4% female and 49.6% male students with mean age of 20+4 and 21+3 years respectively. Mean COVID19ASS scores of male and female students was found to be 18.6 (SD=4.3) and 19.7 (SD=3.8) with no statistically significant difference (p value=0.41, x2= 2.87, df- 3). In factor analysis, age group 18- 20 years, students in first year MBBS, first and second year of paramedical/nursing course, postgraduates, history of COVID19 infection in the past, history of either infection or death due to COVID19 in family or friend were significant risk factors for perseveration and avoidance behavior.
Conclusion: Students who report of pandemic associated anxiety should be thoroughly interviewed for severity of symptoms. This may help in early identification of mal-adaptive behavior, so that early intervention either pharmacological or psychological therapy can be initiated.
Outcome of aneurysmal subarachnoid hemorrhage using Ogilvy and Carter grading system after clipping
Authors: Jha Prabhat , Jha Binit Kumar , Khambu Bikesh , Shrestha Rajendra , Jha Rajiv , Bista Prakash
Published: November 2022

Aneurysmal subarachnoid hemorrhage is a major cause of death and disability. Scales that have been used to prognosticate patients with subarachnoid hemorrhage are Hunt and Hess scale, World Federation of Neurosurgical Societies scale, Fischer grading system. But these scales aren’t inclusive enough to account for all factors related with prognosis of the disease. So Ogilvy and Carter scale has been developed to account for all of these factors.

This study has been done to evaluate the effectiveness of Ogilvy and Carter Score in prognosticating patients with aneurysmal subarachnoid hemorrhage. This is a prospective analytical study conducted at National Academy of Medical Sciences, National Neurosurgical Referral Center, Bir Hospital, Kathmandu, Nepal.

Fifty patients with aneurysmal subarachnoid hemorrhage were included. Hunt and Hess score 1-3 is independently associated with favourable GOS. (p value- 0.000013). Aneurysm size less than or equal to 10 mm is independently associated with favourable GOS. (p value-0.003575). Similarly age less than 50 years was independently associated with favourable GOS. (p value- 0.01354). The incidence of vasospasm, hydrocephalus, electrolyte imbalance, myocardial infaraction and pulmonary edema were higher in patients with Hunt and Hess score > 2, aneurysm size > 10 mm, age >50 years and Fischer score >2.  Higher Ogilvy and carter score was associated with unfavourable GOS at 6 months (p value- 0.002).

In conclusion Ogilvy and Carter scale can serve as a useful for prognosticating patients with aneurysmal subarachnoid hemorrhage.
Sensory ataxic neuropathy with dysarthria and ophthalmoparesis (SANDO) syndrome associated with two heterozygous POLG mutations
Authors: Sasikumar Sheetal , Jaisukhalal Jaisurya
Published: November 2022

Polymerase gamma is a mitochondrial DNA polymerase, that is responsible for the replication of the mitochondrial DNA (mtDNA). It is encoded by the POLG gene, on chromosome 15q25. Various mutations in this gene have been described, with varied phenotypic manifestations. The triad of sensory ataxic neuropathy, dysarthria, and ophthalmoparesis (SANDO) has been reported only in a small group of patients with POLG mutations. We report the case of a male, who presented with phenotype of SANDO syndrome and and was found to have two pathogenic, heterozygous mutations in the POLG gene.