bluuebunny/crossref_metadata_2025 huggingface dataset:
An analysis of the Treatment of Impotence based on the Theory of Qi and Chemistry of the Five Viscera
Authors: Gao Yiping , Liu Jianguo
Published: August 2024

The five organs gasification for the human body fluid, gas, blood, essence and other vital substances all the time transit and mutual transformation process. Penile erectile function is inseparable from the five organs mutual qi function, five organs qi function malfunction of the penis impotence. Blame the heart for the loss of heart and spirit, heart qi insufficiency, heart yang lack of warmth, heart blood deficiency, blame the liver for liver qi stagnation, liver blood deficiency, liver meridian uncomfortable, blame the spleen for the yang deficiency, dampness and evil trapped in the spleen, blame the lungs for the qi insufficiency, the loss of propaganda and purge, and blame the kidney for the yin and yang deficiencies. Through the theory of qi and chemistry of the five viscera, the dysfunction of qi and chemistry of the five viscera is used to describe the pathogenesis of impotence and the selection of treatment prescriptions and medicines, and combined with the joint dialectical treatment of multiple viscera, providing new ideas for the treatment of impotence in Chinese medicine.
Research Progress on the Mechanism of Action of Moxibustion
Authors: Ma Zhenzhen , Ren Yuanyuan
Published: August 2024

Moxibustion therapy for the treatment of diseases has the advantages of wide indications and stable efficacy, and its mechanism of action is an important issue in the field of acupuncture and moxibustion. The mechanism of action of moxibustion therapy is an important issue in the field of acupuncture and moxibustion. Through the collation and analysis of literature related to moxibustion treatment of various diseases in the past ten years, the mechanism of action of moxibustion therapy was summarized from the effects of moxibustion drugs, the effects of moxa smoke, the nervous system, the immune system, and the metabolism of the organism. In this paper, we summarize the research progress on the mechanism of action of moxibustion to provide reference for the clinical use of moxibustion therapy in the treatment of diseases.
Research Status of External Treatment of Traditional Chinese Medicine in the Treatment of Knee Osteoarthritis
Authors: Shu Yang , Yu Wang , Yan Cheng
Published: August 2024

Knee osteoarthritis (KOA) is one of the common and frequent clinical diseases, and its pathogenesis is not fully understood. Compared with modern medicine, there are many methods of TCM treatment for KOA, including internal administration of TCM and staining of TCM, smoking of TCM, acupuncture, massage and other external treatment methods of TCM.
To Explore the Research Progress of Traditional Chinese Medicine on the Pathogenesis of Alzheimer's Disease
Authors: Huang Xiangxiang , Yuan Youcai
Published: August 2024

Alzheimer’s disease, as the most common type of dementia, has become an important public health problem due to the lack of effective diagnosis and treatment measures. Traditional Chinese medicine has outstanding advantages in the prevention and treatment of AD. This article will summarize the pathogenesis and treatment methods of AD in traditional Chinese medicine, in order to provide help for further clinical prevention and treatment of AD.
Research Progress on the Pain Management Model of Children's Tumor Patients
Authors: Song Kaiyang , Cao Haixia
Published: August 2024

According to the latest data released by the National Cancer Research Institute of the World Health Organization, the number of new cancers and deaths in China ranked first in the world in 2020, so cancer treatment has become the focus of attention in the field of health care [1]. There are important challenges in the treatment of pain management and soothing treatment of tumor patients. In order to improve the quality of life of cancer patients, there is an urgent need to solve relevant medical problems in China [2]. Therefore, in the process of anti-tumor treatment, it is very important for pain assessment and pain management of children. It can be seen from the literature that the pain management of childhood tumor patients has not been perfect [3]. Timely, standardized, effective and long-term pain management and control is crucial. This article aims to make a brief review of the current situation of children's tumor pain management, pain assessment tools, and the research progress of children's tumor patient management model.
Research Progress of Massage on Repair of Peripheral Nerve Injury based on ‘Macrophages’
Authors: Yang Linlin , Yuan Haiguang , Yu Boqiang , He Yingtao
Published: August 2024

The repair of peripheral nerve injury is a difficult problem in clinical treatment. As a mechanical stimulation, massage has achieved good results in the clinical treatment of peripheral nerve injury. It can promote the circulation of blood and lymph, accelerate the repair of injured nerves, and improve the metabolic function of the body, but its mechanism remains to be explored. The activation and activation of macrophages, the occurrence of Wallerian degeneration, and the activation of Schwann cells play a huge role in the process of Tuina repair of damaged nerves. Therefore, macrophages provide objective evidence for the repair of peripheral nerve injury by massage.
New Progress in Molecular Genetics Research of Albinism
Authors: Cui Ruoyue , Zhang Danli , Li Jianlei , Zhou Lifei , Zhang Pingping , Li Yali
Published: August 2024

Albinism is a clinical and genetic heterogeneity disease associated with reduced melanin biosynthesis, characterized by visual system defects, manifested as poor vision, accompanied by varying degrees of pigment deficiency. The pigment deficiency can affect the eyes, skin, and hair in Oculocutaneous Albinism (OCA) or Oculocutaneous Albinosis (OA) that only affects the eyes. Currently, 21 genes related to albinism have been identified, including 7 OCA related genes (TYR, OCA2, TYRP1, SLC45A2, SLC24A5, LRMDA, and DCT), 1 OA related gene (GPR143), 1 FHONDA (SLC38A8), 1 CHS related gene (LYST), and 11 PHS related genes (HPS1, AP3B1, HPS3, HPS4, HPS5, HPS6, DTNBP1, BLOC1S3, BLOC1S6, AP3D1, and BLOC1S5). This article reviews the progress of molecular genetics research on albinism, with the aim of providing new ideas for prenatal or early diagnosis of albinism patients.
Acute Asymptomatic Vasculitic Infarct in Patients with Meningitis
Authors: Madhavrao Vikhe Pramod
Published: August 2024

Tuberculous meningitis (TBM) is the most life - threatening form of extrapulmonary tuberculosis and the most common presentation of neurotuberculosis. TBM patients with infarcts are reported to be three times more fatal than patients without infarct. Contrast enhanced magnetic resonance imaging (MRI) is more sensitive than CT for the detection of ischemic changes, edema secondary to inflammation and basal meningeal inflammation. we reviewed the acute asymptomatic vasculitic infarct (by DWI MRI brain imaging) in 41 patients with tuberculous meningitis encountered during a 2 year period. MRI DWI imaging shows asymptomatic acute vasculitic infarct in 13 patients (31%). Thalamus was the most common site of infarct found in 7 patients (53.84%) followed by basal ganglion in 4 patients (30.76%). One patient had uncal (7.6%) and 1 patient had splenium infarct.
The Paths for Higher Vocational Colleges of Culture and Tourism to Serve Rural Revitalization: Taking Nanchong Vocational College of Culture and Tourism as an Example
Authors: Liu Zhou
Published: August 2024

Rural revitalization is an essential part of achieving Chinese-style modernization, an inevitable choice for common prosperity, and an important vehicle for the high-quality development of colleges and universities. At present, there are issues such as insufficient service awareness and capabilities, single service forms, supply-demand mismatch, and inadequate incentive and safeguard mechanisms in the service of rural revitalization by higher vocational colleges of culture and tourism. The solutions are to effectively improve the service awareness and capabilities of faculty and staff, enrich service forms and carriers, bridge the gap between supply and demand, and reform incentive safeguard mechanisms.
Enhanced Cloud Computing Security Based on Single to Multi Cloud Systems
Authors: Ojha Pranav
Published: August 2024

Cloud computing has increased rapidly in many organizations and then it's utilized. Cloud computing provides safe data. Cloud computing provides many advantages in terms of low cost and accessibility of data. Ensuring the security of cloud computing is a major factor in the cloud computing environment, as users often store sensitive information with cloud storage providers but these providers may be untrusted. Dealing with "single cloud" providers is predicted to become less popular with customers due to risks of service availability failure and the possibility of malicious insiders in the single cloud. A movement towards "multi - clouds", or in other words, "inter clouds" or "cloud - of - clouds" has emerged recently. We propose the recent research related to single and multi - cloud security and address possible solutions. It is found that the research into the use of multi - cloud providers to maintain security has received less attention from the research community than the use of single clouds. This work aims to promote the use of multi - clouds due to their ability to reduce security risks that affect the cloud computing user. We proposed the AES algorithm can explore the cloud sharing to multiple clouds. This algorithm protects secure to personal information, financial records, and other confidential records. The system is highly effective in accuracy.
The Growth and Development of Medicine in Medieval India: The Age of the Delhi Sultans
Authors: Kamble Sayali Vinayak
Published: August 2024

This article meticulously traces the evolution of medical services and public health in India, from the ancient civilization of the Harappans, through the reign of Ashoka in the Mauryan Empire, to the influence of Buddhist teachings, and the extensive development of Ayurvedic and Unani medicine. Highlighting the significant contributions of Ashoka to public health, the propagation of medical knowledge under Buddhism, and the foundational aspects of Ayurveda, it delves into the origins and expansion of Unani medicine in India, facilitated by Indo - Persian and Greco - Arab influences. The narrative underscores the establishment of healthcare systems, hospitals, and the dissemination of medical knowledge across different dynasties, including the Delhi Sultanate and the Mughal Empire, showcasing the integration of medical practices over centuries. The emphasis on public health, sanitation, and the provisioning of medical aid across these periods illustrates a rich history of medical evolution that underscores the importance of healthcare in the socio - political fabric of ancient and medieval India, offering insights into the development of a healthcare ethos that prioritized the well - being of its people.
A Novel Topic Segmentation Approach for Enhanced Dialogue Summarization
Authors: Ren Zheng
Published: August 2024

Dialogue summarization aims to distill a given conversation into a brief and focused summary. The challenge lies in the diverse perspectives of participants and the frequent shifts in topics throughout the dialogue. These factors make it difficult to extract and highlight the most significant information effectively. To tackle this challenge, we introduce a novel topic segmentation method that assigns distinct topics to dialogue segments while accounting for their importance and influence within the entire conversation. Our method's performance has been validated on two public benchmark datasets, CSDS and SAMSUM, demonstrating significant improvements in accuracy and coherence. The results show that our approach not only captures the essential content of dialogues more precisely but also enhances the overall quality and coverage of the summaries. This work provides a fresh approach to dialogue summarization and highlights its potential for practical application.
Membangun Pola Parenting Berkeadilan Gender (Analisis Gender Terhadap Pemberdayaan Perempuan Dan Anak Oleh Rifka Annisa Wcc Di Gunung Kidul Dalam Praktik Pekerjaan Sosial)
Authors: Shofiyatuz zahroh
Published: August 2024

Diskursus tentang pola pengasuhan (parenting) menjadi isu krusial di tengah wacana kesetaraan gender yang semakin meluas dalam beberapa dekade tarakhir. Isu-isu tentang kesetaraan gender menjadi satu narasi yang coba diletakkan menjadi wacana global oleh kelompok-kelompok feminis, dengan menekankan pengarusutaman gender di dalam semua sektor kehidupan masyarakat. Oleh karena itu, Rifka Annisa WCC bersama mahasiswa praktikum dan peneliti dari UIN Sunan Kalijaga Yogyakarta berkolaborasi melakukan program pengabdian kepada masyarakat di daerah Gunugn Kidul, dengan upaya-upaya pemberdayaan terhadap perempuan dan anak dalam rangka mencegah kekerasan terhadap perempuan dan anak berbasis gender, dan membangun pola pengasuhan yang berkeadilan gender. Metode pelaksaan pemberdayaan ini dilakukan dengan langkah-langkah partisipasi aktif dengan peserta pemberdayaan, melalui sistem kelas edukasi kepada perempuan, laki-laki dan remaja. Hasil yang dicapai dari proses pemberdayaan ini adalah, baik laki-laki dan perempuan yang terlibat di dalam kelas edukasi memiliki pemahaman tentang keadilan gender secara teoritis, hal itu diketahui dari hasil pre-test dan post-test yang dilakukan oleh penyelenggara pemberdayaan kepada para peserta.
Kata kunci: gender, pemberdayaan, edukasi
Implementasi Program Toilet Training Dalam Menumbuhkan Kemandirian Anak Usia Toddler Di Kelompok Bermain
Authors: Nurbaiti Inayah , Wulandari Retno , Fahmi Fahmi
Published: August 2024

Toilet training young children is an essential milestone in a child's journey towards independence. This study explored the implementation and outcomes of a structured toilet training program in a playgroup setting. The aim is to assess its effectiveness in fostering independence in toddlers aged 1.5 to 3 years. The program takes a gradual approach, emphasizing positive reinforcement and consistency in the routine. This research uses a qualitative approach with a case study type of research. The data collection techniques used included observations of participating toddlers over six months, with data collected through interviews with teachers and direct observation during playgroup activities. The data analysis technique used is Miles and Huberman. The research results showed that, first, in the Al-Fatih KB, 5 of the 14 children had difficulty using the toilet. Second, teachers' structured and consistent approach has proven effective in helping children understand and internalize toilet use skills. Third, the supporting factors in training children's independence in using toddler toilets at Al-Fatih KB Palembang City include good cooperation between teachers and parents, mental and psychological readiness of children, mature age, and complete and adequate facilities and infrastructure in Toilet Training learning. Meanwhile, the inhibiting factors include the child's age, mental and psychological not being ready to learn Toilet Training and the lack of cooperation from parents who still use disposable diapers on their children.
Uso seguro de medicamentos: una aproximación desde el proceso de enfermería
Authors: Villanueva Angel Humberto , Galán González Edna Fabiola , Romero Abril July Johana , Pérez Becerra Viviana
Published: August 2024

Objetivo: Reflexionar sobre la propuesta de integración del proceso enfermero con la farmacología para promover la seguridad del paciente en la práctica clínica. Desarrollo: Los medicamentos son fundamentales para el cuidado de la salud, el tratamiento de enfermedades y la prevención de complicaciones. Sin embargo, su uso generalizado ha contribuido a generar problemas de salud pública, como el uso inadecuado, reacciones adversas, errores de medicación y eventos adversos, que pueden limitar los objetivos terapéuticos y causar efectos no deseados. Se reconoce que las enfermeras no solo administran medicamentos, también promueven su uso seguro, previenen errores y apoyan a los pacientes y sus familias, sustentados en planes de cuidado objetivos, demostrando un compromiso continuo con la excelencia clínica y el cuidado centrado en la persona. En este sentido, emerge el proceso enfermero como estructura sistemática que garantiza y promueve intervenciones y acciones de enfermería con fundamentación científica, por otro lado, la farmacología ofrece una comprensión integral de los medicamentos y exige dominar conceptos de farmacocinética y farmacodinamia para proporcionar un cuidado individualizado que responda a las necesidades identificadas. Conclusiones: Al adoptar un enfoque sistemático y holístico que abarque desde la valoración inicial de las personas y el medicamento, hasta la evaluación continua de resultados y respuestas humanas, los profesionales de enfermería pueden identificar y mitigar riesgos potenciales asociados con el uso de medicamentos.
Adaptación al modelo de altman z2 score como indicador del comportamiento de la estabilidad financiera
Authors: Solórzano Hernández Reynaldo , Rojo Gutiérrez Marco , Velázquez Pompeyo Rene
Published: August 2024

Las empresas bancarias también vigilan el comportamiento de su Estabilidad Financiera, siendo de relevancia mayúscula debido al giro de negocio que desarrollan y su contribución al flujo de dinero en la economía. Para ello, en algunos países utilizan métodos de análisis financieros tradicionales de composición y tendencias financieras, pero también utilizan el llamado método de estimación de insolvencia de Altman Z - Score, en su versión base (Z) y variantes (Z1 y Z2). El objetivo de esta investigación es implementar la adaptación al modelo de Altman Z2 - Score como indicador del comportamiento de la estabilidad financiera aplicado en un banco de Nicaragua para el año 2023. Se utilizó el método analítico sintético, paradigma pragmático por lo tanto de enfoque mixto y su diseño es de triangulación concurrente. Lo cualitativo se respalda con entrevistas a expertos financieros; lo cuantitativo con la data de los estados financieros históricos de la Superintendencia de Bancos y de Otras Instituciones Financiera (SIBOIF) del periodo 2016 - 2022. Se sistematizó la información para aplicar el modelo de regresión lineal múltiple con el cual se explicó la incidencia de las variables independientes, liquidez (X1), rentabilidad (X2 y X3) y deuda (X4), en la nota final sobre la estabilidad financiera (Z2), como variable dependiente. Se obtuvo una nueva fórmula Z3= -0.275 + 1.090 X1 + 0.596 X2 + 0.840 X3 + 2.371 X4 basada en la terminología bancaria y con un criterio de decisión fundamentado en el índice de solvencia mínimo establecido por la SIBOIF a las entidades bancarias. El banco de Nicaragua en estudio superó el criterio de decisión lo que indica que es una institución con solvencia para el año 2023.
USO OFF-LABEL DA SEMAGLUTIDA NO TRATAMENTO DE OBESIDADE: UMA REVISÃO DE LITERATURA.
Authors: DE SÁ Alecxandra Cruz Pereira , CALLOU CINTHIA SILVA , COSTA FRANCISCA VIVIA TEXEIRA , DE SOUSA EDUARDA JOAQUINA COSTA , Texeira Emerson Therlley Sousa , MARQUES ANA EMILIA FORMIGA
Published: August 2024

O presente artigo discute a obesidade como uma doença crônica que tem implicações significativas para a saúde pública em todo o mundo. A obesidade está associada a complicações metabólicas, como resistência à insulina, hipertensão e dislipidemia, que podem levar a doenças cardiovasculares e diabetes tipo 2. Além disso, a obesidade pode causar doença hepática gordurosa não terapêutica. Uma perda de peso modesta, entre 5% e 10%, tem sido demonstrada como capaz de reduzir as complicações relacionadas à obesidade e melhorar a qualidade de vida. No entanto, manter essa perda de peso apenas com mudanças no estilo de vida pode ser desafiador. Intervenções no estilo de vida, como atividade física, redução da ingestão calórica e terapia comportamental, são recomendadas, juntamente com opções de tratamento médico adjuvante, como o uso de agonistas do receptor do peptídeo 1 semelhante ao glucagon (GLP-1RA). Esses medicamentos funcionam ativando os receptores GLP-1, o que pode levar à perda de peso, além de melhorar o controle glicêmico. A semaglutida é um exemplo de GLP-1RA que foi inicialmente aprovado para o tratamento do diabetes tipo 2, mas também tem sido explorado como uma opção terapêutica promissora para a obesidade. Uma revisão sistemática dos estudos busca avaliar o efeito antiobesidade e a segurança dos agonistas do receptor GLP-1 em pacientes com sobrepeso ou obesidade, especialmente aqueles sem diabetes, para melhor compreensão de seu papel na promoção da saúde e qualidade de vida.
Cartas de C&T para o mundo: quando as vozes dos estudantes vão para além dos muros da universidade
Authors: Sousa Ada Lima Ferreira de , Medeiros Josué Anuar Costa de , Silva Larissa Cândido Gomes da
Published: August 2024

O projeto de extensão Cartas de C&T para o mundo objetivou divulgar, no Instagram, textos de graduandos em Ciências & Tecnologia da UFRN, matriculados em componentes curriculares da área de Práticas de Leitura e Escrita, sobre temas socialmente relevantes. Tem-se como resultado interações positivas na conta @cartascet em abril (55 curtidas e 7 comentários) e de julho a setembro de 2021 (38 curtidas e 3 comentários), primeiro período em que o projeto esteve ativo, e de abril a outubro de 2023 (quase 300 contas alcançadas), quando o perfil esteve reativado. Entende-se, com base na interação dos internautas com a conta, não só pela quantidade mas principalmente pelo teor dos comentários, que o projeto tem contribuído com a reflexão, dentro e fora da universidade, sobre leitura, escrita e C&T.
Extensão educacional: biblioteca digital interativa de cálculo para os discentes de graduação da Faculdade de Biotecnologia do ICB-UFPA
Authors: Freitas Victória Carollyne Costa , Abelém Bianca Rabelo , Silva Pedro Lucas Auzier da , Cardoso Simone De Aviz
Published: August 2024

O projeto visou a criação de uma biblioteca digital interativa de cálculo, utilizando-se de recursos textuais e audiovisuais para sua elaboração, além de realizar sua vinculação à página institucional dos cursos da Faculdade de Biotecnologia (FaBiotec). O proposito do projeto de extensão foi solucionar o problema das reprovações nas disciplinas de cálculo pelos discentes da FaBiotec, além de preservar os materiais didáticos utilizados em sala de aula pelos docentes, auxiliar na aprendizagem dos discentes de maneira mais descontraída por meio de uma forma adaptada em biblioteca interativa; facilitando desse modo, o acesso por todos os discentes dos cursos da FaBiotec.
STOCK NOVA CRUZ (DOMÍNIO SÃO JOSÉ DO CAMPESTRE, PORÇÃO NE DA PROVÍNCIA BORBOREMA): GEOLOGIA E PETROGRAFIA
Authors: Dantas Alana Régia , Galindo Antônio Carlos , Medeiros Vladimir Cruz de , Cavalcante Rogério , Souza Raquel Franco de
Published: August 2024

O Stock Nova Cruz (SNC) localizado na porção SSE do Domínio São José do Campestre, possui uma área aflorante em torno de 12 km2 e uma forma aproximadamente subcircular, é intrusivo em ortognaisses tonalíticos a monzograníticos pertencentes ao Complexo Serrinha - Pedro Velho de idade riaciana (c.a 2,2 Ga). Composicionalmente as rochas do stock são monzogranitos leucocráticos (minerais máficos entre 6,9 a 9,2%), tendo a biotita como máfico principal (entre 3,3 a 4,3%) e titanita, allanita, minerais opacos, epídoto, apatita e zircão como demais acessórios. Baseado em critérios de campo é possível inferir que o alojamento deste corpo se deu possivelmente em ambiente Tardi a Pós-tectônico no contexto da orogênese Brasiliana/Panafricana, submetido a um campo de stress em regime frágil em nível crustal raso. O Stock ainda apresenta evidências de que a cristalização do magma se deu principalmente de forma fracionada, com a presença de volume considerável de fluidos tardimagmáticos enriquecidos em voláteis (H2O e CO2) responsáveis pelo desenvolvimento de fases minerais secundárias (clorita, mica branca e carbonato) além do desenvolvimento relativamente extensivo de texturas mirmequíticas e granofíricas.
NOTA EDITORIAL Vol. 59 (04/2024) RA’E GA – O ESPAÇO GEOGRÁFICO EM ANÁLISE
Authors: Breunig Fábio Marcelo
Published: August 2024

A RA’E GA – O ESPAÇO GEOGRÁFICO EM ANÁLISE apresenta a comunidade científica, nacional e internacional, o primeiro volume de 2024 (V.59 – 04/2024 - DOI: http://dx.doi.org/10.5380/raega.v59i0), que reúne artigos com diferentes temáticas correlatas ao conhecimento Geográfico e de outros campos do conhecimento científico.Esta edição da Revista mantêm o fluxo de publicação em idioma inglês e português. Esta estratégia objetivou preservar a estrutura de construção dos textos e aumentar o acesso dos diferentes leitores.A RA’E GA agradece as(os) autoras (es), a equipe editorial, as(os) editoras (es) de secção, as revisoras (es), em especial as/os que atuaram neste volume (AGNES DE ARAUJO, SIRIUS SOUZA, TONY SAMPAIO            MARIA SALVADOR, MÁRCA SILVA, ZENO CROCETTI, JULIANO ANDRES, FÁBIO MARCELO BREUNIG, ARTHUR SANTOS, ISABEL PEDRON, JAKELINE BARATTO, CLÁUDIA VALE, ELIAS BERRA, ROSEMERI MORO) e ao Programa de Apoio às Publicações Científicas Periódicas da UFPR.Todas estas atividades são fundamentais para o desenvolvimento científico brasileiro e foram essenciais para a qualidade do presente volume.
ANÁLISE DOS MÉTODOS E TÉCNICAS NAS PESQUISAS DA GEOGRAFIA ELEITORAL CONTEMPORÂNEA, NO BRASIL
Authors: Guimarães Glauber Cardoso , Cigolini Adilar Antônio
Published: August 2024

Este artigo objetiva classificar os procedimentos metodológicos utilizados por trabalhos da Geografia Eleitoral no Brasil e sugerir caminhos possíveis a novas pesquisas do campo acadêmico. Os estudos foram classificados de acordo com 4 tipologias: (i) a representação cartográfica descritiva e estatística; (ii) métodos quantitativos espaciais; (iii) comportamento individual do eleitor e (iv) lógica social do comportamento eleitoral. Foram acrescidas as categorias: (v) estado da arte / conhecimento e (vi) outras. O artigo apresente duas etapas: levantamento/classificação e sugestão de possíveis caminhos. Para realizar o levantamento foram feitas pesquisas no catálogo de teses e dissertações da CAPES com o termo geografia eleitoral e acrescentados os filtros temporal, a partir de 2016, e áreas de conhecimento Ciência Política e Geografia em 63 sites de periódicos da área de Geografia, na plataforma Scielo e na plataforma Google Acadêmico. O levantamento resultou em 45 trabalhos acadêmicos. Evidenciou-se que a distribuição dos estudos é igualitária entre as áreas de Ciência Política e Geografia. Há predomínio de métodos quantitativos, avaliando o recorte da Ciência Política, enquanto que em Geografia há uma distribuição semelhante das tipologias. Na segunda etapa sugerimos três possíveis rumos, com o intuito de reduzir algumas lacunas diagnosticadas: o uso de teorizações que enfoquem no espaço geográfico como causalidade dos resultados eleitorais e a neurociência e os estudos sobre Guerra Híbrida. Concluímos que a diversidade de métodos é natural, em uma ciência com mais de um século de história e sugerimos uma pesquisa em anais de congressos e grupos de pesquisa, para levantamentos futuros.
NOTA DITORIAL Vol.60 (8/2024) RA’E GA – O ESPAÇO GEOGRÁFICO EM ANÁLISE
Authors: Breunig Fábio Marcelo
Published: August 2024

A RA’E GA – O ESPAÇO GEOGRÁFICO EM ANÁLISE apresenta a comunidade científica, nacional e internacional, o segundo volume de 2024 (V.60 – 08/2024 - DOI: http://dx.doi.org/10.5380/raega.v60i0.95324), que reúne artigos com diferentes temáticas correlatas ao conhecimento Geográfico e de outros campos do conhecimento científico.Esta edição da Revista mantêm o fluxo de publicação em idioma inglês e português. Esta estratégia objetivou preservar a estrutura de construção dos textos e aumentar o acesso dos diferentes leitores.A RA’E GA agradece as(os) autoras (es), a equipe editorial, as(os) editoras (es) de secção, as revisoras (es), em especial as/os que atuaram neste volume (revisores ROBERTO GOERL, MÁRCIA SILVA, ZENO CROCETTI, EUGÊNIA PEREIRA, EDNER BAUMHARDT, ANDRESSA FERLA, TARIK CUCHI, CLÁUDIA VALE, MARCOS TORRES, FABIO MARCELO BREUNIG, ELIAS F BERRA; TONY SAMPAIO, APARECIDO ANDRADE, ISABEL PEDRON, FERNANDO PASINI, LIDIA KUHN, VANDOIR BOURSCHEIDT, RENATO BEPPLER SPOHR, ROMÁRIO TRENTIN, INOCENCIO BORGES NETO, ARTHUR SANTOS, LEILA LIMBERGER, ISADORA HADDAD, ALEXANDRE UHLMANN, CLÁUDIA VALE) e ao Programa de Apoio às Publicações Científicas Periódicas da UFPR.Todas estas atividades são fundamentais para o desenvolvimento científico brasileiro e foram essenciais para a qualidade do presente volume.
SIMULATION OF HYDROLOGICAL SCENARIOS IN THE JAGUARI/RS RIVER WATER BASIN USING THE SWAT MODEL
Authors: Von Ende Dotto Antônio , De Souza Robaina Luís Eduardo , Trentin Romário
Published: August 2024

Hydrological models are computational tools that can assist in the management of river basins through modeling the water balance. This modeling allows for the predicting impacts caused by the uncertainty of the future climate that affects socioeconomic activities and environmental conditions. In this sense, this study applied the Soil and Water Assessment Tool (SWAT) model to simulate hydrological scenarios in the Jaguari River Basin. The simulation period carried out was determined based on the availability of data for modeling and validation. Therefore, in this context of data scarcity, the calibration period was from 2013 to 2016 and the validation period was from 2017 to 2019. The manual calibration method used ensured a coherent water balance in all simulated hydrological processes, achieving good results for flow, with an efficiency coefficient of 0.74 and correlation of 0.86 during calibration, and coefficients of 0.72 and 0.85 during validation. After adjusting the model, an alternative scenario was inserted, preserving the riparian forests of the Jaguari River Basin hydrographic network, resulting in notable changes, such as greater groundwater storage and increased flow due to the greater fraction of water in the base flow. The hydrological simulation demonstrated success, highlighting the modeling capacity even in the face of limitations in data acquisition at national level. It is recommended, in future work, to apply alternative scenarios of land use or climate change, taking advantage of the adjusted calibration obtained.
PENGARUH DIGITAL MARKETING, BRAND IMAGE TERHADAP KEPUTUSAN PEMBELIAN (STUDI PEMBELIAN BATIK DI E-COMMERCE TIKTOK SHOP)
Authors: Aprian Aditama Rizky Ramadhan , Larasati Nike , Paramita Pratita Mutya
Published: August 2024

Penelitian ini bertujuan untuk mengetahui pengaruh digital marketing dan brand image terhadap keputusan pembelian baju batik di aplikasi tiktok shop. Penelitian ini juga bertujuan untuk mengetahu pengaruh kepercayaan konsumen memediasi hubungan digital marketing dan brand image terhadap keputusan pembelian baju batik di aplikasi tiktok shop. Jenis penelitian ini adalah kuantitatif dengan jumlah sampel sebanyak 100 responden. Teknik pengumpulan data yang digunakan adalah kuesioner. Metode analisis data dalam penelitian ini adalah analisis regresi linier berganda menggunakan software SPSS. Hasil penelitian menunjukkan bahwa variabel digital marketing berpengaruh signifikan terhadap keputusan pembelian dengan nilai t-hitung 3,396 > t-tabel 1,660, dan nilai signifikansi sebesar 0,001 < 0,05. Variabel brand image berpengaruh signifikan terhadap keputusan pembelian dengan nilai t-hitung 4,913 > t-tabel 1,660. Dapat disimpulkan bahwa Dengan menggunakan strategi digital marketing yang tepat, bisnis dapat menjangkau lebih banyak konsumen, membangun hubungan dengan mereka, dan mendorong mereka untuk membeli produk atau layanannya. Dengan menggunakan digital marketing secara efektif, bisnis dapat meningkatkan penjualan dan keuntungannya. Bisnis dapat menggunakan berbagai strategi untuk membangun citra merek yang positif, seperti menyediakan produk atau layanan berkualitas tinggi, memberikan layanan pelanggan yang baik, dan membangun komunikasi yang efektif dengan konsumen.
Análise da Síndrome de Burnout em estudantes dos cursos noturnos de um centro universitário
Authors: Gonçalves Ana Clara Moreira , Baldez Ana Luísa Neiva , Neves Lyvia de Paula , Resende Júlia Cristina , Rodrigues Maria Cláudia Cândida , Silva Márcio Aurélio da
Published: August 2024

O estudo investigou a prevalência e os fatores associados à Síndrome de Burnout entre estudantes de cursos noturnos de um Centro Universitário em Araguari, Minas Gerais, utilizando uma abordagem quantitativa e um estudo observacional de corte transversal, sendo coletados dados de 339 alunos de 13 cursos diferentes. Os resultados revelaram uma alta prevalência da síndrome entre os estudantes, com 91,44% apresentando algum grau de sintomatologia associada e a análise por áreas de conhecimento indicou diferenças estatisticamente significativas, com uma maior prevalência em cursos de humanas, além disso, foram observadas variações na prevalência da síndrome ao longo dos períodos do curso, especialmente em Administração e Enfermagem. No entanto, não foi encontrada uma associação significativa entre a dupla jornada de trabalho e estudo e o desenvolvimento da síndrome, mas por outro lado, a prática regular de atividade física foi identificada como um fator de proteção, com estudantes que a praticam apresentando um menor risco de desenvolver a síndrome. Estes resultados destacam a importância de abordagens holísticas na promoção da saúde mental dos estudantes universitários, incluindo medidas de apoio institucional e incentivo à prática de atividades físicas como estratégias de prevenção do Burnout.
Decoding the genetic landscape of autism: A comprehensive review
Authors: Al-Beltagi Mohammed , Saeed Nermin Kamal , Bediwy Adel Salah , Bediwy Eman A , Elbeltagi Reem
Published: August 2024

BACKGROUND

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by heterogeneous symptoms and genetic underpinnings. Recent advancements in genetic and epigenetic research have provided insights into the intricate mechanisms contributing to ASD, influencing both diagnosis and therapeutic strategies.

AIM

To explore the genetic architecture of ASD, elucidate mechanistic insights into genetic mutations, and examine gene-environment interactions.

METHODS

A comprehensive systematic review was conducted, integrating findings from studies on genetic variations, epigenetic mechanisms (such as DNA methylation and histone modifications), and emerging technologies [including Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 and single-cell RNA sequencing]. Relevant articles were identified through systematic searches of databases such as PubMed and Google Scholar.

RESULTS

Genetic studies have identified numerous risk genes and mutations associated with ASD, yet many cases remain unexplained by known factors, suggesting undiscovered genetic components. Mechanistic insights into how these genetic mutations impact neural development and brain connectivity are still evolving. Epigenetic modifications, particularly DNA methylation and non-coding RNAs, also play significant roles in ASD pathogenesis. Emerging technologies like CRISPR-Cas9 and advanced bioinformatics are advancing our understanding by enabling precise genetic editing and analysis of complex genomic data.

CONCLUSION

Continued research into the genetic and epigenetic underpinnings of ASD is crucial for developing personalized and effective treatments. Collaborative efforts integrating multidisciplinary expertise and international collaborations are essential to address the complexity of ASD and translate genetic discoveries into clinical practice. Addressing unresolved questions and ethical considerations surrounding genetic research will pave the way for improved diagnostic tools and targeted therapies, ultimately enhancing outcomes for individuals affected by ASD.
PENGABULAN IZIN POLIGAMI DIKARENAKAN TELAH MENIKAH SIRRI (Studi Kasus Terhadap Putusan Pengadilan Agama Pariaman)
Authors: Mahmudi Elva
Published: August 2024

Studi ini mengkaji tentang Putusan Pengadilan Agama Pariaman Nomor 532/Pdt.G/2019/PA.Prm tentang Pengabulan Izin Poligami dengan Alasan Telah Menikah Sirri. Permasalahannya adalah suami mengajukan permohonan poligami karena telah menikah sirri dengan calon istri kedua, serta dikabulkan atas dasar Pasal 4 ayat (2) huruf a dan Pasal 5 ayat 1 UU No.1/1974. Studi ini menggunakan penelitian lapangan (field research). Data di kumpul melalui metode yuridis normatif yaitu pendekatan yang dilakukan berdasarkan bahan hukum utama dengan cara menelaah teori-teori, konsep, asas hukum serta peraturan perundang-undangan yang berhubungan dengan penelitian ini. Setelah data dikumpul diolah dengan cara menelaah data yang diperoleh dari informasi dan literatur terkait, mengklasifikasikan data dan menyusun berdasarkan kategori-kategori dan setelah data tersusun langkah selanjutnya adalah menarik kesimpulan berdasarkan data yang ada. Studi ini menemukan hasil pertimbangan  utama majelis hakim dalam mengabulkan izin poligami adalah berdasarkan mashlahah yaitu kemaslahatan keluarga. Selanjutnya hakim mepertimbangkan Pasal 4 ayat (2) huruf a yaitu isteri tidak menjalankan kewajiban sebagai isteri dan Pasal 5 ayat 1, isteri pertama telah membuat surat persetujuan izin poligami. Di samping itu hakim juga mempertimbangkan adanya penyataan suami untuk berlaku adil kepada seluruh isterinya. Analisis penulis terhadap pertimbangan hakim adalah bahwa kemaslahatan yang dijadikan pertimbangan tidak realistis. Pertimbangan Pasal 4 ayat (2) huruf a Undang-Undang Nomor 1 Tahun 1974 tidak sesuai dengan fakta di persidangan. Pertimbangan penggunaan pasal 5 ayat 1, terbukti dipersidangan bahwa isteri pertama sudah mencabut persetujuan atau izin poligami yang diberikannya. Sedangkan surat pernyataan suami untuk berlaku adil tidak ada jaminan untuk bisa direalisasikan. Sehingga menurut penulis hakim telah keliru dalam memberikan keputusan izin poligami pada perkara Nomor 532/Pdt.G/2019/PA.Prm. Disamping itu, menurut analisa penulis, seharusnya permohonan tersebut dinyatakan oleh majelis hakim tidak dapat diterima (NO) karena tidak memenuhi syarat materil. Karena kalau dilihat dari permohonan yang diajukan oleh pemohon maka sebenarnya permohonan tersebut tidak memenuhi syarat materil karena pada dasarnya permohonan izin poligami diajukan sebelum dilakukannya poligami tersebut. Sementara dalam perkara ini pemohon telah nyata melakukan pernikahan sirri sebelum adanya izin dari Majelis Hakim untuk melakukan poligami. Oleh karena itu jelas permohonan ini tidak memiliki dasar hukum sebagai permohonan izin poligami.
PERAN PENINGKATAN KUALITAS PEMBELAJARAN PENDIDIKAN AGAMA ISLAM MELALUI MANAJEMEN YANG EFEKTIF DI SMP AL-AZHAR MEDAN
Authors: Tanjung Nurmahani , Irwansyah Irwansyah , Wirda Farid
Published: August 2024

Tulisan ini bertujuan untuk mengevaluasi dan meningkatkan kualitas pembelajaran Pendidikan Agama Islam di SMP Al-Azhar Medan melalui penerapan manajemen yang efektif. Pendidikan Agama Islam memiliki peran sentral dalam membentuk karakter dan nilai-nilai moral siswa, oleh karena itu, manajemen pembelajaran yang efektif menjadi kunci dalam mencapai tujuan tersebut. Penelitian ini menggunakan metode observasi, wawancara, dan analisis dokumen untuk mengidentifikasi tantangan utama dalam pembelajaran Pendidikan Agama Islam di sekolah ini. Hasil penelitian menunjukkan bahwa ada beberapa kendala dalam hal kurikulum, sumber daya, serta proses pembelajaran yang memengaruhi kualitas pendidikan agama di SMP Al-Azhar Medan. Selanjutnya, penelitian ini mengusulkan strategi perbaikan, termasuk pengembangan kurikulum yang relevan, peningkatan pelatihan guru, dan penggunaan teknologi pendidikan yang lebih efektif. Implementasi manajemen yang lebih baik dalam pengelolaan sumber daya dan evaluasi pembelajaran juga diusulkan untuk memastikan pencapaian tujuan pendidikan agama. Dengan menerapkan strategi-strategi ini, penelitian ini bertujuan untuk meningkatkan kualitas pembelajaran Pendidikan Agama Islam di SMP Al-Azhar Medan, sehingga siswa dapat memahami nilai-nilai agama secara lebih mendalam, mengembangkan karakter moral yang kuat, dan menjadi anggota masyarakat yang berkontribusi positif. Melalui pendekatan manajemen yang efektif, harapannya adalah dapat memberikan kontribusi positif dalam pengembangan pendidikan agama Islam di tingkat sekolah menengah.
Research on the Policy Agenda of Elderly Education Moving towards National Legislation from the Perspective of Multiple Streams Theory
Authors: Li Hui
Published: August 2024

In the new era, the concept of elderly education is gradually gaining acceptance. From the perspective of Multiple Streams Theory, abundant data not only reveal the severe challenges faced by elderly education but also become key indicators for measuring its development trend. The high public attention and focal events intertwined accelerate the prominence of problem streams. The attention of government departments to elderly education issues, the deep insights and unique suggestions of NPC deputies and experts and scholars provide rich intellectual resources for policy formulation. Additionally, the guidance of advanced party concepts, the solid guarantee of government administration according to law, and the widespread resonance of national emotions together constitute a strong driving force in the political stream. When the problem, policy, and political streams converge, the policy window opens accordingly, initiating a new chapter for the development of elderly education at the national legislative level.
“鹅腿”狂欢的生成与连接逻辑——马莱茨克大众传播场模式深析
Authors: 李 紫妍
Published: August 2024

近日，北京高校圈中，一名叫做“鹅腿阿姨”的流动摊贩意外走红，在互联网引起传播热潮。随即，在上海高校圈中，又出现一名叫“糖葫芦叔叔”的流动摊贩，其出售的糖葫芦同样被众多高校学生哄抢。为什么高校流动摊贩会在一夜之间席卷社交网络，引起高校学生的竞相追捧？本文根据马莱茨克大众传播场模式，试从传播者、讯息和接收者三方面对“鹅腿”事件进行深入解析，以探究“鹅腿”事件如何通过身份认同、从众心理、游戏狂欢等方式迅速升温，在虚拟空间中实现不同个体、群体甚至整个社会的连接与互动，从而为洞察数字时代的流量传播因果链，以及数字社会的文化生态与社会心理提供新的视角。
Unlocking synergies: Smart cities and the dynamic business model approach
Authors: Perätalo Sari
Published: August 2024

This interview comprises the opening part of a doctoral defense in which Christian Nielsen acted as Sari Perätalo’s opponent. The defense took place on November 24, 2023, at Oulu Business School, Finland, and the topic was “In search of a business model approach for smart cities.” After the discussion conveyed in this paper, the doctoral defense focused on specific research outcomes, methodologies, and theories and illustrated that the PhD candidate indeed was extremely knowledgeable about the subject and should be awarded the degree of a PhD.
Surgeon Prescribing Patterns And Perioperative Risk Factors Associated With Prolonged Opioid Use After Total Shoulder Arthroplasty
Authors: Pezzulo Joshua D. , Farronato Dominic M. , Juniewicz Robert , Kane Liam T. , Kellish Alec S. , Davis Daniel E.
Published: August 2024

Introduction:

The opioid epidemic in the United States has contributed to a notable economic burden and increased mortality. Total shoulder arthroplasty (TSA) has become more prevalent, and opioids are commonly used for postoperative pain management. Prolonged opioid use has been associated with adverse outcomes, but the role of surgeons in this context remains unclear. This study aims to investigate the incidence and risk factors of prolonged opioid utilization after primary TSA.

Methods:

After obtaining institutional review board approval, a retrospective review of 4,488 primary total shoulder arthroplasties from 2014 to 2022 at a single academic institution was conducted. Patients were stratified by preoperative and postoperative opioid use, and demographic, clinical, and prescription data were collected. Prescriptions filled beyond 30 days after the index operation were considered prolonged use. Multivariate analysis was conducted to determine the independent risk factors associated with prolonged opioid utilization.

Results:

Among 4,488 patients undergoing primary TSA, 22% of patients developed prolonged opioid use with 70% of prolonged users being opioid-exposed preoperatively. Independent risk factors of prolonged use include patient age younger than 65 years (Odds Ratio (OR) 1.02, P < 0.001), female sex (OR 1.41, P < 0.001), race other than Caucasian (OR 1.36, P = 0.003), undergoing reverse TSA (OR 1.28, P = 0.010), residing in an urban community (OR 1.33, P = 0.039), preoperative opioid utilization (OR 6.41, P < 0.001), preoperative benzodiazepine utilization (OR 1.93, P < 0.001), and increased postoperative day 1-30 milligram morphine equivalent (OR 1.003, P < 0.001).

Discussion:

Nearly 22% of patients experienced prolonged opioid use, with preoperative opioid exposure being the most notable risk factor in addition to postoperative prescribing patterns and benzodiazepine utilization. Surgeons play a crucial role in opioid management, and understanding the risk factors can help optimize benefits while minimizing the associated risks of prolonged opioid use. Additional research is needed to establish standardized definitions and strategies for safe opioid use in orthopaedic surgery.
Management of Xylazine-Induced Soft-Tissue Necrosis: A Review of 20 Cases
Authors: Retrouvey Helene , Meyer Maximilian A. , Ipaktchi Kyros , Maertens Andrew , Folchert Matthew , Lauder Alexander
Published: August 2024

Purpose:

The illicit injection of xylazine has recently been designated as an emerging public health threat. The use of this drug is associated with devastating soft-tissue necrosis that may lead to limb amputation. This study aimed to (1) report cases of soft-tissue injury from xylazine and (2) describe a staging and management algorithm for wounds related to xylazine use.

Methods:

A retrospective review was conducted to identify patients treated for xylazine-related soft-tissue necrosis at a trauma center. Clinical cases, treatment strategy, and available outcomes were presented. In addition, a comprehensive literature search was conducted using the keywords “xylazine” and “soft tissue.”

Results:

The management of seven patients with xylazine-related upper extremity soft-tissue necrosis was included, in addition to summarizing findings of five studies reporting on 13 additional cases. These cases were managed with local wound care (2 patients), soft-tissue reconstruction (4 patient), osseous reconstruction (1 patient), and limb amputation (10 patients).

Discussion:

Acute treatment of xylazine-related soft-tissue necrosis is ideal to minimize morbidity and prevent limb loss. Management strategies of these wounds should be based on the depth of tissue involvement. Superficial ulceration involving the skin and subcutaneous tissue (Stage 1) should be managed with local wound care. Deeper ulceration involving tendons and/or muscle (Stage 2) requires surgical débridement and soft-tissue reconstruction. Deeper ulceration involving bone (Stage 3) requires osseous débridement and reconstruction. Finally, when all tissues in the extremity are involved (Stage 4), amputation is often necessary.
PENGARUH LINGKUNGAN KERJA DAN KOMPENSASI TERHADAP PRODUKTIVITAS KARYAWAN PADA PT. LINTAS SAMUDERA JAYA
Authors: Dewi Kesuma Margaretha , Nirmala Sari Tika
Published: August 2024

This research aims to determine the influence of the work environment and compensation on employee productivity at PT. Lintas Samudera Jaya. The testing techniques used in this research used research instrument tests, descriptive statistical tests, classical assumption tests, multiple linear regression tests and hypothesis tests. The type of research used in this research uses quantitative research. The data sources used in this research are primary data sources and secondary data sources. The results obtained in this research are that the work environment variable does not have a positive and significant influence on employee productivity, however the compensation variable has a positive and significant influence on employee productivity. Simultaneous test results showed that the work environment and compensation together had a positive and significant effect on employee productivity at PT. Lintas Samudera Jaya