bluuebunny/crossref_metadata_2025 huggingface dataset:
RISK FACTORS FOR DEVELOPING UPPER LIMB CELLULITIS AFTER BREAST CANCER TREATMENT
Authors: Engin O. , Şahin E. , Sarıbay E. , Dilek B. , Akalın E.
Published: September 2022

Cellulitis is one of the most important troubling complications of breast cancer treatment. Therefore, elucidating the risk factors for cellulitis in patients that have undergone breast cancer treatment is crucial. This is a retrospective medical record study among 523 patients who had received breast cancer treatment and were referred to the Lymphedema Clinic. Data on age, height, weight, BMI (body mass index), education level, arm dominance, history of previous surgery, axillary lymph node dissection, radiotherapy, and chemotherapy were noted. The time between operation and onset of lymphedema, duration of lymphedema, history of cellulitis, and number of cellulitis attacks were recorded. Circumference measurements were taken at four points on the upper limb. Univariate analysis showed that longer duration of lymphedema, larger circumference of the unaffected arm and larger circumference of the arm with lymphedema were associated with higher risk of cellulitis (p=0.008, p=0.007, p< 0.001, respectively). The incidence of cellulitis was higher in patients with lymphedema than patients who had no lymphedema (p< 0.001). Moreover, the frequency of cellulitis was higher in patients with lower education level (p=0.015). It was deter-mined that patients with cellulitis needed more compression garments (p< 0.001) and multi-layered bandage therapy (p< 0.001) than those without. Regression analysis revealed that presence of lymphedema (p=0.036), duration of lymphedema (p=0.048), radiotherapy (p=0.01) and educational level (0.019) are significantly associated with developing upper extremity cellulitis. It is important to consider these risk factors for the prevention and management of cellulitis in patients who undergo treatment for breast cancer. Early detection and treatment of lymphedema also remains essential for these patients.
ISL NEWS
Authors: NEWS ISL
Published: September 2022

ISL NEWS June 2022
Investigation of Dense Family of Closure Operations
Authors: Son Nguyen Hoang , Demetrovics J. , Thi Vu Duc , Thuy Nguyen Ngoc
Published: September 2022

As a basic notion in algebra, closure operations have been successfully applied to many fields of computer science. In this paper we study dense family in the closure operations. In particular, we prove some families to be dense in any closure operation, in which the greatest and smallest dense families, including the collection of the whole closed sets and the minimal generator of the closed sets, are also pointed out. More important, a necessary and sufficient condition for an arbitrary family to be dense is provided in our paper. Then we use these dense families to characterize minimal keys of the closure operation under the viewpoint of transversal hypergraphs and construct an algorithm for determining the minimal keys of a closure operation.
Serverless High-Performance Computing over Cloud
Authors: Petrosyan Davit , Astsatryan Hrachya
Published: September 2022

HPC clouds may provide fast access to fully configurable and dynamically scalable virtualized HPC clusters to address the complex and challenging computation and storage-intensive requirements. The complex environmental, software, and hardware requirements and dependencies on such systems make it challenging to carry out our large-scale simulations, prediction systems, and other data and compute-intensive workloads over the cloud. The article aims to present an architecture that enables HPC workloads to be serverless over the cloud (Shoc), one of the most critical cloud capabilities for HPC workloads. On one hand, Shoc utilizes the abstraction power of container technologies like Singularity and Docker, combined with the scheduling and resource management capabilities of Kubernetes. On the other hand, Shoc allows running any CPU-intensive and data-intensive workloads in the cloud without needing to manage HPC infrastructure, complex software, and hardware environment deployments.
A Color-Texture-Based Deep Neural Network Technique to Detect Face Spoofing Attacks
Authors: Rusia Mayank Kumar , Singh Dushyant Kumar
Published: September 2022

Given the face spoofing attack, adequate protection of human identity through face has become a significant challenge globally. Face spoofing is an act of presenting a recaptured frame before the verification device to gain illegal access on behalf of a legitimate person with or without their concern. Several methods have been proposed to detect face spoofing attacks over the last decade. However, these methods only consider the luminance information, reflecting poor discrimination of spoofed face from the genuine face. This article proposes a practical approach combining Local Binary Patterns (LBP) and convolutional neural network-based transfer learning models to extract low-level and high-level features. This paper analyzes three color spaces (i.e., RGB, HSV, and YCrCb) to understand the impact of the color distribution on real and spoofed faces for the NUAA benchmark dataset. In-depth analysis of experimental results and comparison with other existing approaches show the superiority and effectiveness of our proposed models.
Toward Programmability of Radio Resource Control Based on O-RAN
Authors: Pencheva Evelina N. , Atanasov Ivaylo I.
Published: September 2022

Open Radio Access Network (O-RAN) is a concept that aims at embedding intelligence at the network edge and at disaggregating of network functionality from the hardware. The paper studies how the O-RAN concept can be used for optimization of radio resource management. The research focuses on adaptive radio resource allocation based on predictions of device activity. For narrowband devices which send sporadically small volumes of data, a feature is defined which enables a device with no activity for a short time to suspend its session and to resume it moving in active state. Dynamic configuration of the inactivity timer based on prediction of device activity may further optimize radio resource allocation. The paper studies an O-RAN use case for dynamic radio resource control and presents the results of emulation of the RESTful interface defined between the O-RAN non-real-time and near real-time functions.
Robust adaptive beamforming using modified constant modulus algorithms
Authors: Ahmad Zeeshan , Jaffri Zain ul Abidin , Hassan Najam ul , Chen Meng
Published: September 2022

This paper addresses the self-nulling phenomenon also known as the self-cancellation in adaptive beamformers. Optimum beamforming requires knowledge of the desired signal characteristics, either its statistics, its direction-of-arrival, or its response vector. Inaccuracies in the required information lead the beamformer to attenuate the desired signal as if it were interference. Self-nulling is caused by the desired signal having large power (high SNR) relative to the interference signal in case of the minimum variance distortion less response beamformer, and low power desired signal in the case of the constant modulus algorithm (CMA) beamformer, which leads the beamformer to suppress the desired signal and lock onto the interference signal. The least-square constant modulus algorithm is a prominent blind adaptive beamforming algorithm. We propose two CMA-based algorithms which exploit the constant modularity as well as power or DOA of the desired signal to avoid self-nulling in beamforming. Simulations results verify the effectiveness of the proposed algorithms.
Model of fractional-order resonant wireless power transfer system for optimal output
Authors: Prasad Ravneel , Sharma Krishneel , Gulabdas Bhavish , Mehta Utkal
Published: September 2022

Wireless Power Transfer (WPT) technology has recently gained popularity in applications and research topics. It enables the transfer of electrical energy from a source to a load without connecting wires physically. The WPT system is commonly studied classically using integer order capacitors and inductors. Nonetheless, such integer order based systems have drawbacks, such as low output power, poor transmission efficiency and sensitivity to parameter variations. This paper proposes a fractional order resonant WPT circuit whereby both the transmitting and receiving ends are composed of a fractional capacitor and inductor to overcome such problems. In this paper, the overall performance is studied based on its output power and efficiency considering a series-parallel topology. The effect of fractional order in fractal elements will be analyzed to observe the optimal combination of components to achieve the maximum output power with higher efficiency. Through a comparative analysis of the results, several combinations of circuit parameters can provide a theoretical understanding for implementing an experimental system.
A potential flooding version number attack against RPL based IOT networks
Authors: Rouissat Mehdi , Belkheir Mohammed , Belkhira Hichem Sid Ahmed
Published: September 2022

Routing protocol for low power and lossy networks (RPL) has been proposed for power, memory, and processing constrained devices. Owing to their constrained, RPL-based networks are exposed to a wide range of security attacks that mainly include control message tampering. In this paper we propose and study a modified version number attack, based on flooding the network by falsified incremented version numbers. The obtained results show that the modified attack led to an immense increase in the overhead, 1426%, compared with the attack-free case, and an increase of 182 % in the total energy consumption. When it comes to PDR a degradation to 4.7% has been recorded, affecting the reliability of the network. On the other hand, the latency also showed an increase from 0.24 s in the attack-free case to 0.89 s, which is mainly due to the high congestion created by the attack.
Energy estimation of QCA circuits: An investigation with multiplexers
Authors: Khan Angshuman , Parameshwara M. C. , Bahar Ali Newaz
Published: September 2022

Quantum-dot Cellular Automata (QCA) is a rival to complementary-metal-oxide-semiconductor (CMOS)-based technology and one of the most cutting-edge nano-scale technologies. The multiplexer is a fundamental component in the fields of nano communication and nano computation. The investigative item of this article is the QCA multiplexer, and a handful of the best multiplexers were chosen as samples for the current experiment. The QCA layouts were designed in the QCADesigner-2.0.3 simulation engine environment, and the best one was reported after successfully experimenting on a total of eight samples. The co-ordinate-based energy was estimated using QCADesigner-E (QDE), and the non-adiabatic energy waste was investigated using QCAPro. According to the coordinates-based technique, the overall energy waste of the best energy-saving QCA multiplexer is 5.90 meV, with an average energy loss per cycle of 0.537 meV. Another approach, QCAPro-based, was used to estimate the energy loss at three different levels of tunneling at a constant temperature, yielding an overall energy loss of approximately 12 to 15 meV for the energy-efficient multiplexers..
Analytical method for joint optimization of FFE and DFE equalizations for multi-level signals
Authors: Dikhaminjia Nana , Tsiklauri Mikheil , Kiguradze Zurab , He Jiayi , Chada Arun , Mutnury Bhyrav , Drewniak James L.
Published: September 2022

Channel equalization is the efficient method for recovering distorted signal and correspondingly reducing bit error rate (BER). Different type of equalizations, like feed forward equalization (FFE) and decision feedback equalization (DFE) are canceling channel effect and recovering channel response. Separate optimization of tap coefficients for FFE and DFE does not give optimal result. In this case FFE and DFE tap coefficients are found separately and they are not collaborating. Therefore, the final equalization result is not global optimal. In the present paper new analytical method for finding best tap coefficients for FFE and DFE joint equalization is introduced. The proposed method can be used for both NRZ and PAM4 signals. The idea of the methodology is to combine FFE and DFE tap coefficients into one optimization problem and allow them to collaborate and lead to the global optimal solution. The proposed joint optimization method is fast, easy to implement and efficient. The method has been tested for several measured channels and the analysis of the results are discussed.
Stoma-Related Complications: A Single-Center Experience and Literature Review
Authors: Benedek Zalán , Kocsis Loránd , Bauer Orsolya , Suciu Nicolae , Sorlea Sorin , Crăciun Călin , Georgescu Rareș , Coroș Marius Florin
Published: September 2022

Introduction: The creation of an abdominal stoma is a common procedure performed by surgeons as a part of the treatment for benign and malignant conditions in general surgery. Stoma formation is simple, but sometimes the associated postoperative complications have an impact on the patients’ physical and psychological state. The majority of complications do not require reoperation, but when it is indicated, we have to assess the most appropriate option for the patient.

Material and Methods: We conducted a retrospective study in a single surgical center, the Department of Surgery, Mureș County Hospital, Târgu Mureș, Romania, using data from patients who have been admitted under elective conditions for stoma-related complications between 2005 and 2019.

Results: A total number of 877 ostomies (653 colostomies and 224 ileostomies) were performed, and 157 patients (17.9%) developed some type of stoma complication and required surgical intervention. The mean age was 64.5 ± 2.1 years, with a male-female ratio of 1.3 to 1. The leading comorbidities included cardiovascular disease (52.2% of cases), obesity (22.2%), and diabetes (18.4%). Parastomal hernia was the most frequent complication (47.5% of cases), followed by stoma prolapse (23.4%), parastomal stenosis (20.3%), and parastomal infection (8.2%). There was an association between age and the type of complication: parastomal hernia, stoma prolapse, and stenosis were more frequent in the elderly; parastomal infection was more prevalent in young patients. A longer hospital stay was observed in case of parastomal hernia.

Conclusions: Stoma formation is associated with significant morbidity. Typically, the complications appear in the elderly. Conservative treatment is essential, but some of the late complications, such as parastomal hernia, stoma stenosis, stoma prolapse, and parastomal infection, require a surgical solution. Parastomal hernias are the most common complications, frequently associated with comorbidities and prolonged hospitalization.
Remote-sensing detection of points for the heavy vehicles crossing in the large lowland riverbeds
Authors: Ostrowski Piotr
Published: September 2022

The erosion-resistant culminations of the alluvial subsoil occurring in the riverbeds of some rivers may play the role of “geological bridges” under favorable hydrological conditions, constituting places convenient for forcing by heavy vehicles. The article discusses the possibility of remote-sensing identification of such places based on a common analysis of aerial images, high-resolution satellite images and Digital Terrain Models based on Airborne Laser Scanning. The result of the work was the identification of relief forms in the valley bottoms of large lowland indicating the available locations for heavy vehicles forcing the bed. This allowed for the formulation of general assumptions of the SYSTEM OF DESIGNING ZONES CONVENIENT FOR CROSSROADS USING AIR PLATFORMS.
False actions of the aviation fire protection system caused by disturbances in power circuits
Authors: Głyda Krzysztof , Szelmanowski Andrzej , Sulkowski Jarosław , Pazur Andrzej
Published: September 2022

The article presents the results of simulation tests of the SSP-FK aviation fire protection system and the identification of the main causes of its false operation on many airplanes and helicopters of the Polish Armed Forces with the use of a diagnostic simulator built at ITWL. The results of the performed statistical analyzes pointing to the execution blocks as the key factors in false fire signaling are discussed. Selected test results of the developed simulation model of the actuator unit under the conditions of disturbances occurring in its supply circuits (in particular instantaneous voltage drops) are presented. The effectiveness of the presented test method with the use of a simulation model of a fire protection system, which can be used to train the engineering and aviation service and pilots, and to support the work of the Aircraft Accident Investigation Commission, was pointed out.
Identification of Regularities in Relation Between Prices on Primary and Secondary Housing Market in Selected Cities in Poland
Authors: Kokot Sebastian
Published: September 2022

The purpose of this study is to identify regularities in the price relations between primary and secondary housing markets. The primary market and the secondary market are two related but quite differentiated sub-segments of the residential market. They particularly differ in the qualitative features of their traded objects and, consequently, also in the prices recorded in their trading. Nevertheless, they remain under the influence of the same main factors of a macroeconomic nature. This gives rise to the research hypothesis that prices of flats quoted in the sub-segments of the residential market remain in specific relationships with one another.

In an attempt to verify this hypothesis, the paper presents the results of an analytical work on the search for regularities in the relationship between prices on primary and secondary housing markets in selected Polish cities. The regularities concern the dynamics and structure of price relation indices constructed for the research. They also include classification analyses. The findings of the research have revealed, inter alia, that in the majority of the cities under study, prices of flats in the primary markets are higher than prices in the secondary markets. However, situations in which the reverse happens periodically (sometimes occasionally) are not rare. The examined relations are not permanent and are subject to relatively large, irregular fluctuations over time. It is possible to distinguish groups of cities which are relatively similar in this respect, but these similarities are not strong.
Econometric Models of Real Estate Prices with Prior Information. Mixed Estimation
Authors: Doszyń Mariusz
Published: September 2022

The purpose of this paper is to estimate econometric models with sample and prior information. Prices of land property for residential development in Szczecin are modeled (the price level was determined for 2018). Modeling property prices only based on sample data generates numerous problems. Transaction databases from local real estate markets often contain a small number of observations. Properties are frequently similar, which results in low variability of property characteristics, and thus – low efficiency of parameter estimators. In such a situation, the impact of some features cannot be estimated from the sample data. As a solution to this problem, the paper proposes econometric models that consider prior information. This information can be, for example, in the form of property feature weights proposed by experts. The prior information will be expressed in the form of stochastic restrictions imposed on the model parameters. In the simulation experiment, the predictive power of mixed estimation models is compared with two kind of models: OLS models and model with only prior information. It turned out that mixed estimation results are superior with regard to formal criteria and predictive abilities.
Interpositional arthroplasty with temporal muscle flap – a surgical alternative for condylar ankylosis of the temporomandibular joint
Authors:   Department of Dentistry, Higher Education University of Feira de Santana, Feira de Santana, BA, Brazil, Bastos Carlos , Gomes Ana ,   Department of Dentistry, Dom Bosco University Center, São Luís, MA, Brazil, Jesus Julia ,   Department of Dentistry, State University of Feira de Santana, Feira de Santana, BA, Brazil, Pereira Almira ,   Department of Dentistry, State University of Feira de Santana, Feira de Santana, BA, Brazil, Cerqueira Caio ,   Department of Oral and Maxillofacial Surgery, Hospital Emec/Niro Health Center/HGCA, Feira de Santana, BA, Brazil, Leite Thiago ,   Department of Oral and Maxillofacial Surgery, Hospital Emec/Niro Health Center/HGCA, Feira de Santana, BA, Brazil
Published: September 2022

Ankylosis of the temporomandibular joint (TMJ) is characterized by a bony or fibrous fusion between the articular fossa and the condyle. It represents one of the greatest therapeutic challenges in oral and maxillofacial surgery. Several treatments have been used for its management, such as gap arthroplasty, interpositional arthroplasty, and TMJ reconstruction with autogenous bone graft and alloplastic prostheses. A 39-year-old Black male patient developed a complex mandibular symphysis fracture associated with bilateral high condylar fractures after a motorcycle accident. In the first approach, osteosynthesis was performed to reduce and fix symphysis fractures and conservatively treat the condyles. However, the patient did not proceed with physiotherapy and adequate follow-up, evolving into bilateral ankylosis. Subsequently, he underwent interpositional arthroplasty with a temporal muscle flap. The treatment of ankylosis is imperatively surgical and aims to release the joint and reanatomize the region, restoring functionality to the stomatognathic system. The choice of technique depends on many factors, including age. In children, gap arthroplasty is the most frequent choice because it helps in the centrality of condylar growth. In adult patients, gap arthroplasty with interposition of the temporal muscle is eligible, as it restores function and reduces the recurrence of bone fusion and consequent re-ankylosis.
The outcome of acute kidney injury in patients admitted to intensive care unit at King Abdulaziz University Hospital in Jeddah, Saudi Arabia: a retrospective cohort study
Authors: Batwie Raghad , A.Organji Rahaf , Alaklouk Reham , Alotaibi Afrah , Alharbi Nada , Gari Shahlaa , Alharbi Mariam , Alamri Reem , Hozali Hanadi , Kadi Hanan
Published: September 2022

Background: Acute kidney injury (AKI) is a common health problem among critically ill patients with a growing prevalence and variable causes. AKI outcome is still unknown worldwide and especially in the Kingdom of Saudi Arabia. This study aimed to determine short-term outcomes among Saudi patients with AKI.
Methods: A retrospective study was conducted in King Abdulaziz University Hospital (KAUH), Jeddah, Saudi Arabia. Medical records of adult patients who developed AKI at the KAUH intensive care unit (ICU) from January 2019 to December 2021 were reviewed. AKI was diagnosed according to the Kidney Disease Improving Global Outcomes.
Results: A total of 444 medical records were reviewed and AKI was diagnosed in 173 patients (38.9%). The most common causes of AKI were sepsis (44.5%), COVID-19 (31.2%), and hypotension (23%). Over half of the patients' comorbidities in the current study was hypertension. The median length of stay in the ICU and hospital was 6.31 (2.52-16.93) and 16 (6.06-28.92) days, respectively. The death rate among AKI patients was 89%. Renal replacement therapy was required for 40.5%.
Conclusion: AKI was found in 38.9% of all adults admitted to KAUH ICU. The epidemiology and causes of AKI were similar to other studies in the literature. Mortality and length of stay were highly associated with AKI.
Public knowledge and awareness of hepatocellular carcinoma among the Saudi Arabian population
Authors: Jiffry Bilal , Neyaz Yousef , Softah Abdulrhman , Alqahtani Nawaf
Published: September 2022

Background: The studies regarding the public knowledge and awareness of hepatocellular carcinoma (HCC) among the general population in Saudi Arabia and other countries are limited or unavailable. Therefore, our study aims to assess the knowledge and awareness of the most common type of primary liver cancer (HCC) among the general population in Saudi Arabia.
Methods: This analytical cross-sectional study was conducted at the University of Taif, Department of Medicine, to assess the public awareness regarding HCC risk factors, symptoms, methods of diagnosis, screening, and liver function among the Saudi population in 2021. Data were collected using an online questionnaire using the SurveyMonkey website.
Results: A total of 1,028 respondents participated in the study by answering an online questionnaire. Most of the respondents were female (71.1%) between the ages of 18 and 29 years (79.8%), had a university degree (70.1%), were nonhealthcare workers (67.4%), and were from Mecca Province (56.2%). We found that 77.2% of the participants reported knowing the functions of the liver. Considering HCC, 46.4%, 19.6%, 25.3%, and 45.3% reported that they had knowledge considering HCC, its symptoms, risk factors, and screening tests, respectively. In general, we found that 14.2% of the participants had a high level of knowledge about HCC, while 85.8% had a low, inadequate level of knowledge. Moreover, we found that high knowledge was associated with the female gender, high educational level, older age, and working in healthcare provinces.
Conclusion: The findings in this study indicate poor knowledge regarding HCC in the general Saudi population.
El reto de la construcción de la gobernanza del sistema de competitividad, ciencia, tecnología e innovación en el Valle del Cauca. Un desafío para la región
Authors: Caicedo Asprilla Henry , Ríos Obando José Fabián , Cruz Aguilar Pedro León , Ríos Alvarado Arnaldo , Angarita De La Cruz Bernardo , Castillo Tabares Rubén , Jiménez Restrepo Diana Marcela , Vargas García Lina Marcela , Otálora Sevilla Lady , Hernández Gloria Marcela , Castro Caicedo María del Mar , Díaz Bejarano Juan Sebastián
Published: September 2022

El presente documento se enmarca en el componente denominado Gobernanza para la articulación de los investigadores y grupos de investigación con la empresa, el Estado y la sociedad civil y se propone de forma específica examinar alternativas de gobernanza que facilite el ajuste a la institucionalidad, la normativa y las políticas en competitividad, ciencia, tecnología e innovación que contribuyan a la articulación de los investigadores y grupos de investigación con la Empresa, el Estado y la Sociedad Civil, y el producto 1.1 en donde se desarrolla la caracterización, evaluación y consulta de actores del sistema de C&CTI vinculados al proceso de fortalecimiento del sistema de competencias a la conectividad de la gobernanza; donde se llevó a cabo con una muestra heterogénea de 3764 actores de la ciudad de Cali, Buenaventura y Tuluá-Cenvalle del departamento del Valle del Cauca, entre los años 2019-2022. Como instrumentos de recolección, se utilizaron cuestionarios, que midieron las principales dimensiones de la capacidad de los líderes o actores en el proceso de innovación transformativa, entrevistas a profundidad y semiestructuradas, para identificar mecanismos de articulación de la gobernanza, en el cual se fortalecieron los conocimientos de los representantes de diferentes sectores sobre gobernanza.
Social protection of ATO/OUF veterans and their families at the community level
Authors: Kravchenko Oksana , Kucher Halyna
Published: September 2022

The article describes the Uman territorial community as a social community thanks to its extensive system of social institutions, the implementation of the best international practices, the constant expansion of the social welfare spectrum, the focus on the needs of every individual and the necessity to satisfy those needs according to state standards. At the same time, the community establishes a social protection system (social services and social security) for ATO/OUF participants and their families. For this purpose, four social protection programs for 2021-2025 period have been developed and approved for ATO/OUF participants and the families of the fallen (integrated health, welfare, social security programs, adaptation, psychological rehabilitation, vocational training (retraining) for the anti-terrorist operation participants, the families of the Heavenly Hundred, the victims of the Revolution of Dignity, and fighter - volunteers; housing provision for 2021-2025 period for the participants of the anti-terrorist operation/operation of the joint forces and volunteer fighters who participated in the protection of territorial integrity and state sovereignty in the East of Ukraine and for their family members; "Care" social assistance for 2021-2027; national-patriotic education for children and youth for 2021-2025); an Assistance Center has been established for the Participants of the Anti-Terrorist Operation; there has been established the division of military personnel adaptation, assistance for the participants of the anti-terrorist operation, deportees and labor migrants; benefits and social guarantees are provided to participants (utility reimbursement , free meals in preschool and secondary schools for children of ATO participants, rehabilitation in a summer health camp, provision of a one-time financial assistance, free public transportation within the city, purchase of cold water meters, free education for children of the fallen ATO participants in art schools, etc.), medical and psychological assistance is provided in "Harmony" Rehabilitation Complex for People with Special Needs, professional rehabilitation, sports rehabilitation, employment, informational and explanatory work, etc. are provided.
Social prevention of family injury in the territorial community
Authors: Liakh Tetiana , Spirina Tetiana , Klishevych Nataliia
Published: September 2022

For comprehensive, a child needs to be brought up in a family environment, with an atmosphere of happiness, love, understanding, and respect for human dignity. Parents' understanding of the problems of raising children is an important component of family well-being. But today, most conflicts occur precisely in the family environment between spouses and between parents and children. Therefore, the problem of prevention of family dysfunction is an urgent problem for modern society.

The article is devoted to the problems of family dysfunction and its consequences for Ukrainian society; scientific and theoretical provisions for social prevention of family dysfunction are defined and it is emphasized that indicators of family dysfunction are related to economic, social, psychological, and personal reasons. Taking into account the key indicators of disadvantage, the following types of dysfunctional families and their impact on the state of the family are distinguished: conflict, pedagogically incompetent, immoral, antisocial; the terms denoting the phenomenon of family dysfunction were analyzed: dysfunctional family, destructive, dysfunctional, problematic, crisis and family with risks.

The authors emphasize that one of the leading directions of social work with the family is the prevention of family dysfunction, which is carried out through strengthening the institution of the family, preparing young people for married life, forming family values ​​in young people, popularizing the model of responsible parenthood, and which promotes the realization of rights and freedoms of the child, creation of favorable conditions for its development, formation of universal human values, the satisfaction of material and spiritual needs of people. Social prevention of family dysfunction involves a set of measures by social institutions of the community aimed at prevention, limitation and mitigation of risk factors, correction of parents' behavior associated with a threat to the health and social well-being of family members, as well as rehabilitation of those who have experienced its consequences. The activities of social workers are aimed at creating social conditions to meet the needs and interests of families. The effectiveness of preventive intervention depends on the correct choice of the type of prevention, which will be the most expedient for the prevention of family problems in the community.
Overcoming socio-psychological maladaptation of the persons with the acquired and congenital disabilities
Authors: Fushteі Oksana , Franko Nataliia , Sarancha Iryna
Published: September 2022

On the basis of the analysis of the existing philosophical, sociological, psychological and pedagogical approaches there was the theoretical analysis of the domestic and foreign scientific works on the problem of social and psychological maladaptation carried out, there were the external and internal factors of formation of social and psychological maladaptation of the persons with disabilities substantiated. As a result of the theoretical analysis of socio-psychological maladaptation, there are the main elements of this personality trait identified, namely: maladaptive types of the internal picture of the disease and coping strategies, negative trends in self-concept (low or contradictory self-esteem, lack of self-confidence, inexpressive self-acceptance, etc.), destructive emotional states, low level of socio-psychological tolerance. Social factors that cause the emergence of socio-psychological maladaptation include the following: inferiority and dysfunction of the family, lack of education or its low level, impossibility of the professional fulfilment.

There were the psychodiagnostic tools compiled and the peculiarities of social and psychological maladaptation of the persons with the acquired and congenital disabilities empirically studied. Taking into account the identified problems, overcoming socio-psychological maladaptation of the persons with the acquired and congenital disabilities is characterized, which presents the following three blocks: individual psychological assistance to the persons with disabilities (correction of the attitude type to the disease, self-attitude, self-acceptance and self-esteem); work with the families of the disabled people; the information and educational block is aimed at working with the society (overcoming negative socio-psychological stereotypes towards the people with disabilities and encouraging creation of the inclusive environment).
The issue of checks by Vladivostok branch of State Bank in 1920
Authors:   Sakhalin State University, Kiselev A. L.
Published: September 2022

The paper analyzes the issue of the Vladivostok branch of the State Bank of checks with a face value of 1000 rubles in January 1920, which became an attempt to replenish the stocks of banknotes to overcome the financial crisis that arose as a result of the Civil War and military intervention in the Russian Far East. The purpose of the work is to analyze known and, introducing into scientific circulation, identified historical sources that clarify and reveal certain issues when making a decision and organizing the issuance of checks by the Vladivostok branch of the State Bank. The theoretical basis of the study is a systematic approach and a comparative historical method. The author comes to the conclusion about the failure of issuance measures at the issuance stage, due to the intervention of counterfeiters. The failure of the checks increased the influence of foreign exchange in the region. The publication is addressed to researchers of financial policy during the Civil War and intervention in Russia.
Import substitution policy in Russia under conditions of overcoming external sanction pressure
Authors:   Financial University under the Government of the Russian Federation, Shatokhin M. V. , Antropova T. G. ,   Kazan National Research Technical University named after A. N. Tupolev – KAI, Surai N. M. ,   Russian University of Economics named after G. V. Plekhanov, Sepiashvili E. N. ,   Moscow State University of Technology and Management K. G. Razumovsky
Published: September 2022

The article is devoted to revealing the role of import substitution policy in the development of the domestic market. The article examines foreign approaches to the implementation of import substitution. The analysis of the main groups in the commodity structure of Russian imports for the period 2017–2021 is carried out. The results of import substitution of the main commodity groups of imports for the period 2014–2021 are considered. Problems and obstacles in the production of domestic goods are identified. Scenarios for the development of the importsubstituting policy of the state are predicted. The article outlines the priority areas of import substitution policy in Russia.
Features of platelet link of hemostasis in novel coronavirus disease COVID-19.
Authors: Изможерова Н.В. , Попов А.А. , Антропова И.П. , Сайфутдинов Т.М. , Кадников Л.И. , Шамбатов М.А. , Испавский В.Е. , Рябинина А.В.
Published: September 2022

Новая коронавирусная инфекция (COVID-19), вызванная вирусом SARS-CоV-2, представляет собой опасность для многих органов и систем человека. Одной из таких систем является система гемостаза, особенностью поражения которой считается склонность к избыточному тромбообразованию и последующему возникновению тромботических осложнений. Уникальность коагулопатии при новой коронавирусной инфекции связана с повышением уровня фибриногена, D-димера и гиперактивации тромбоцитов за счет снижения количества тромбоцитов наряду с их повышенной деструкцией и снижением продукции. В обзоре приведен анализ публикаций, описывающих частоту, предполагаемые причины и патогенез наблюдаемых при COVID-19 тромбоцитопении и тромбообразования. Рассмотрено влияние новой коронавирусной инфекции непосредственно на функцию тромбоцитов, а также на высвобождение тромбоцитами биологически активных факторов.

The novel coronavirus disease (COVID-19) caused by SARS-CoV-2 virus represents a danger to many human organs and systems, hemostasis is one of them. Characteristic feature of hemostasis lesion is the tendency to excessive thrombus formation and the subsequent occurrence of thrombotic complications. Coagulopathy uniqueness in novel coronavirus infection is associated with an increased level of fibrinogen, D-dimer and platelet hyperactivation due to a decrease in platelets number along with their increased destruction and reduced production. The review presents an analysis of publications describing the frequency, supposed reasons and pathogenesis of thrombocytopenia and thrombosis observed in COVID-19. Direct impact of novel coronavirus infection on platelet function as well as on the release of biologically active factors by platelets, is considered.
Discovery of a Simple Iron Catalyst Reveals the Intimate Steps of C–H Amination to Form C–N Bonds
Authors: Stroek Wowa , albrecht martin
Published: September 2022

Formation of ubiquitous C–N bonds traditionally uses prefunctionalized carbon precursors. Recently, metal-catalyzed amination of unfunctionalized C–H bonds with azides has become an attractive and atom-economic strategy for C–N bond formation, though all catalysts contain sophisticated ligands. Here, we report Fe(HMDS)2 (HMDS = –N(SiMe3)2) as an easy-to-prepare catalyst for intramolecular C–H amination. The catalyst shows unprecedented turnover frequencies (110 h–1 vs 70 h–1 reported to date) and requires no additives. Amination is successful for benzylic and aliphatic C–H bonds (>80% yield) and occurs already at room temperature. The catalyst simplicity enabled for the first time comprehensive mechanistic investigations. Kinetic, stoichiometric, and computational studies unveiled the intimate steps of the C–H amination process, including catalyst resting state and turnover-limiting N2 loss of the coordinated azide, The high reactivity of the iron imido intermediate is rationalized by its complex spin system revealing imidyl and nitrene character.
AI-assisted chemical reaction impurity prediction and propagation
Authors: Mohapatra Somesh , Griffin Daniel
Published: September 2022

Most chemical reactions result in numerous by-products and side-products, apart from the intended major product. While chemists can predict many of the main process impurities, it remains a challenge to enumerate the possible minor impurities and even more of a challenge to systematically predict and track impurities derived from raw materials or those that have propagated from one synthetic step to the next. In this study, we developed an AI-assisted approach to predict and track impurities across multi-step reactions using the main reactants, and optionally reagents, solvents and impurities in these materials, as input. We demonstrated the utility of this tool for a simple case of synthesis of paracetamol from phenol, and provide a generalized framework that covers most chemical reactions. Our solution can be applied to enable (1) faster elucidation of impurities, (2) automated interpretation of data generated from high-throughput reaction screening, and (3) more thorough raw materials risk assessments, with each of these representing key workflows in small molecule drug substance commercial process development.
SEMILLEROS DE INVESTIGACIÓN: ESTRATEGIA PARA EL FORTALECIMIENTO DE LA FORMACIÓN PARA LA INVESTIGACIÓN
Authors: Díaz Bohórquez Carlos Eduardo , Buitrago Rodríguez Jennifer Natalia
Published: September 2022

Los avances científicos y la dinámica de la sociedad hacen un llamado constante a la generación de nuevo conocimiento. Es por esto que las instituciones educativas han fomentado la creación de comunidades de aprendizaje para que articulen el conocimiento que surge entre el currículo y la investigación, siendo los semilleros de investigación una estrategia para tal fin. En este sentido, el Grupo de Investigación en Optimización y Organización de Sistemas Productivos, Administrativos y Logísticos-OPALO de la Universidad Industrial de Santander, ha institucionalizado sus semilleros de investigación como estrategia para el fortalecimiento de la formación para la investigación. De ahí que, ha diseñado y establecido un Plan de Formación para que, con el apoyo de los estudiantes de maestría, profesores cátedra y planta se logre la formación y vinculación de los estudiantes de pregrado en ingeniería industrial. El Plan de Formación de los semilleros de investigación está compuesto de tres fases, en donde la Fase 1 denominada Seminario de Habilidades Investigativas tiene como objeto contextualizar a los estudiantes en el mundo de la investigación científica y desarrollar habilidades esenciales para iniciar con el proceso investigativo mediante una formación metodológica. La Fase 2, está dirigida a estudiantes que han cursado previamente la Fase 1 y que están interesados en continuar con el proceso de aprendizaje a través de las líneas de investigación del grupo. En esta fase los estudiantes desarrollan habilidades básicas de programación en herramientas computacionales de optimización y análisis de datos que contribuyen a la formación integral. Finalmente, la Fase 3 está dirigida para aquellos estudiantes interesados en el desarrollo de propuestas y proyectos de investigación para ser presentados en revistas científicas, eventos académicos y/o como modalidad de trabajo de grado. El impacto que ha tenido los semilleros de investigación en los últimos tres años ha sido la masificación de los mismos en donde, por ejemplo, en los semestres académicos del año 2019 participaron 10 estudiantes de maestría apoyando las sesiones teórico-prácticas y, se certificaron en la Fase 1 163 estudiantes, 39 estudiantes en la Fase 2 y 94 estudiantes de pregrado quienes estuvieron vinculados al grupo OPALO con proyecto de grado bajo la modalidad de trabajo de investigación.
Contribution of the Golgi apparatus in morphogenesis of a virus-induced cytopathic vacuolar system
Authors: Sengupta Ranjan , Mihelc Elaine M , Angel Stephanie , Lanman Jason K , Kuhn Richard J , Stahelin Robert V
Published: September 2022

The Golgi apparatus (GA) in mammalian cells is pericentrosomally anchored and exhibits a stacked architecture. During infections by members of the alphavirus genus, the host cell GA is thought to give rise to distinct mobile pleomorphic vacuoles known as CPV-II (cytopathic vesicle-II) via unknown morphological steps. To dissect this, we adopted a phased electron tomography approach to image multiple overlapping volumes of a cell infected with Venezuelan equine encephalitis virus (VEEV) and complemented it with localization of a peroxidase-tagged Golgi marker. Analysis of the tomograms revealed a pattern of progressive cisternal bending into double-lamellar vesicles as a central process underpinning the biogenesis and the morphological complexity of this vacuolar system. Here, we propose a model for the conversion of the GA to CPV-II that reveals a unique pathway of intracellular virus envelopment. Our results have implications for alphavirus-induced displacement of Golgi cisternae to the plasma membrane to aid viral egress operating late in the infection cycle.
Open circuit fault-tolerant operation of 3-Φ multilevel inverter
Authors: Sunil Manjhi , Rajkumar Jhapte
Published: September 2022

A modified Fault-Tolerant (FT) structure is presented for the five-level Multi-Level Inverter (MLI) in this research work. A self capacitor voltage balancing control regulates the voltage across the capacitor by a half magnitude of the DC source value to produce a five-level output voltage waveform. Furthermore, the self capacitor voltage balancing control reduces complexity and enhances system reliability. A possible Open Circuit (OC) fault in the switches of the proposed structure is further analyzed. On the basis of a comparative analysis between the five-level MLI and the proposed faulttolerant structure, this structure is presented. When compared with the most recent FT topologies, it contains fewer devices. MATLAB/Simulink are used to study the proposed single-phase and three-phase FT structures under pre-fault, fault and post-fault operation.
Performance analysis of shunt active filter based on srf theory using metaheuristic optimization technique for nonlinear loads
Authors: Nidhi Sahu , Sandeep Sahu
Published: September 2022

Power electronic devices play a vital role in manufacturing process, research and development because it delivers high efficiency, low cost, rapid operation, and optimal size. In recent years, power electronic devices have become widely employed in a variety of fields. Harmonics have a substantial impact on power systems and the main sources of harmonics are nonlinear loads and energy conversion devices such as static converters, choppers, cyclo-converters, battery charging systems, and heating elements, among others. To reduce harmonics, different filtration technologies are available, with the shunt active power filter being one of the most significant and effective. The performance of a shunt active power filter based on synchronous reference frame theory is explored and the efficiency is improved utilising the satin bower bird optimization approach.