bluuebunny/crossref_metadata_2025 huggingface dataset:
PENINGKATAN KEMAMPUAN PENYELENGGARAAN PERTANDINGAN OLAHRAGA GULAT PADA MAHASISWA PENJAS UNTAN MELALUI PEMBELAJARAN BERBASIS PROYEK
Authors: Bafadal Muhammad Fachrurrozi
Published: June 2023

Meningkatkan kemampuan penyelenggaraan pertandingan olahraga mata kuliah gulat pada mahasiswa pendidikan jasmani semester 5 tahun 2022 dengan menggunakan model pembelajaran berbasis proyek merupakan tujuan penelitian ini. Metode penelitian ini adalah penelitian tindakan kelas terdapat 2 siklus, tiap siklus terdapat 2 pertemuan yang terdiri dari perencanaan, tindakan, observasi dan refleksi. Sampel penelitian ini berjumlah 15 mahasiswa dan menggunakan Purposive sampling. Hasil penelitian ini menunjukkan, pada pra siklus belum menunjukkan kemampuan menyelenggarakan pertandingan olahraga sebesar 255  poin dengan persentase 21,25% dan masuk kategori kurang sekali, terjadinya peningkatan skor kemampuan menyelenggarakan pertandingan olahraga pada siklus I sebesar 691 poin dengan presentase 57,58% bergerak naik ke kategori cukup dan terus meningkat pada siklus II sebesar 1115 poin dengan persentase 92,91% dan terus merangkak naik  ke dalam kategori Sangat Baik. Kesimpulan dalam penelitian ini adalah kemampuan penyelenggaraaan pertandingan olahraga gulat pada mahasiswa pendidikan jasmani, FKIP Universitas Tanjungpura dapat ditingkatkan melalui model pembelajaran berbasis proyek terlihat dari presentase siklus II sebesar 92,91% dengan kategori Sangat Baik, ini berarti bahwa mahasiswa pendidikan jasmani telah mampu melaksanakan dan memahami serta dapat menjalankan fungsi serta tugas pada setiap anggota panitia penyelenggaraan pertandingan olahraga. Sehingga dalam penyelenggaraan terselesaikan tepat waktu, sesuai peraturan dan sistem pertandingan berjalan dengan lancar.
PEMBENTUKAN KARATERISTIK PESERTA DIDIK MENGARAH PADA PROFIL PANCASILA UNTUK JENJANG PENDIDIKAN DASAR MELALUI MATA PELAJARAN PENDIDIKAN JASMANI OLAHRAGA DAN KESEHATAN
Authors: Octova Adryo
Published: June 2023

Tulisan dari artikel ini bertujuan untuk pembentukankarakteristik peserta didik profil pancasila agar dapatditerapkan dengan baik dan dapat menanamkan karakter profilpancasila dalam dirinya. Metode yang digunakan dalamartikel ini adalah metode kualitatif menggunakan buku, jurnaldan literatur lainnya. Hasil penelitian terdapat bahwa profilpelajar pancasila mempengaruhi perkembangan karakteristikpeserta didik, dimana pembentukan karakteristik tersebutperlu dibentuk sejak dini. Dikarenakan dengan majunyaperkembangan zaman yang dapat memberikan pengaruhpositif maupun sebaliknya, maka dari itu penerapan profilpelajar pancasila sangat memberikan pengaruh terhadapperkambaangan karakteristik peserta didik terutama pada matapelajaran peendidikan jasmani olahraga dan kesehatan melaluisebuah prsses yang bekelanjutan, metode pembelajaran yang tepat. Karakter tidak dapat dibentuk dengan mengandalkanteori saja melainkan harus dibarengi dengan praktek yang pada akhirnya akan memunculkan kebiasaan yang baik. Dengan adanya strategi yang dilaksanakan oleh guru diharapkan para peserta didik menjadi pribadi yang sesuaidengan profil pelajar pancasila terutama dalam kehidupansehari hari baik dilingkungan sekolah maupun di lingkunganmasyarakat. Dimana hal ini sesuai dengan topik yang telahdiangkat yaitu pembentukan karakteristik peserta didik yang mengarah pada profil pancasila untuk jenjang pendidikandasar melalui mata pelajaran pendidikan jasmani olahraga dan kesehatan
PEMBELAJARAN PENDIDIKAN JASMANI DICAPAI MELALUI METODE PROBLEM SOLVING
Authors: Tamba Raymond Pardamean
Published: June 2023

Metode Penelitian yang digunakan adalah tindakan kelas yang dimana merupakan salah satu upaya dalam memecahkan masalah yang dihadapi guru selama ini pada saat proses pembelajaran mereka.Proses pembelajaran meliputi pembelajaran pendidikan jasmani di kelas serta praktik di laboratorium dan lapangan.Guru memegang peranan penting dalam pelaksanaannya penelitian tindakan kelas.Guru mengetahui masalah yang dihadapi siswa di kelas.Di dalam pendidikan jasmani, kemampuan motorik siswa bervariasi.Guru bertanggung jawab dalam merencanakan,bertindak, melakukan, mengamati dan merefleksi.Guru juga dapat dibantu oleh pasangan atau pakar.Dua faktor penting dalam penelitian tindakan kelas khususnya pendidikan jasmani adalah penggunaan media pengajaran dan gaya mengajar
PENGARUH BUDAYA ORGANISASI DAN KEPEMIMPINAN TERHADAP KINERJA PENGURUS CABANG OLAHRAGA DAN PRESTASI ATLET PERCASI 1 DELI SERDANG
Authors: Sitanggang Liston , Dewi Rahma , Supriadi Amir , Akhmad Imran , Nurkadri Nurkadri , Mesnan Menan
Published: June 2023

Tujuan dari penelitian ini adalah untuk menganalisis budaya organisasi dan kepemimpinan Dewan cabang olahraga dan Prestasi Olahragawan dan dampaknya melawan PERCASI Kabupaten Deli Serdang. Itu objek penelitian adalah anggota Dewan Cabang Olahraga Catur Komite Olahraga Kabupaten Deli Serdang, Populasi dalam penelitian  ini adalah Anggota Pengurus Cabang Olahraga PERCASI Kabupaten Deli Serdang dengan menggunakan rumus Solvin. Jenis data yang diperlukan dalam penelitian ini merupakan data primer dan data sekunder. Sumber data primer adalah diperoleh dari hasil penelitian empiris melalui penyebaran kuesioner kepada Badan Cabang Olahraga, sedangkan sumber data sekunder penulis peroleh dalam bentuk siap pakai meliputi tentang organisasi profil PERCASI Deli Serdang. Metode pengumpulan data yang digunakan adalah wawancara dan kuesioner. Alat analisis data yang digunakan dalam penelitian adalah linier berganda analisis regresi.
Effects of mono- and disaccharides on fruit gel formation
Authors: Kambulova Yuliia , Overchuk Nataliya , Kohan Olena
Published: June 2023

DOI: 10.24263/2310-1008-2022-10-2-7 http://nuft.edu.ua/doi/doc/ujfs/2022/2/7.pdf
New data to the Moroccan Myrmeleontiformia (Nemopteridae, Myrmeleontidae, Ascalaphidae) fauna
Authors: Ábrahám Levente
Published: June 2023

Between 2008-2010 the author six times three-week-long collecting trips were carried out in Morocco. During this survey, total of 2369 specimens (Nemopteridae: 52, Myrmeleontidae: 2089, Ascalaphidae: 228) were collected by net, light and portable light trap methods. 6 nemopterid, 53 myrmeleontid and 8 ascalaphid species were found. A total of 41% (28 species) of the collected species were the first record for the Moroccan fauna. Palpares martini Weele, 1907 syn. n., and Palpares germaini Navás, 1919 syn. n. are new junior synonyms of Palpares angustus Mclachlan, 1898; Solter micheli sp. n. is a new species compared to Solter naevipennis Navás, 1913. New synonyms are Cueta arenosa (Navás, 1913) syn. n. a new junior synonym of Cueta lineosa (Rambur, 1842); Neuroleon danieli (Lacroix 1922) syn. n., a new junior synonym of Neuroleon gafsanus (Navás, 1921) comb. n., Distoleon divisus (Navás, 1913) syn. n. a new junior synonym of Neuroleon cuigneti (Navás, 1912) comb. n., Neuroleon egenus stirpis Steffan, 1971 without description is a nomen nudum but Neuroleon stirpis Steffan, 1975 stat. n., is a valid species. Creoleon antennatus (Navás, 1914) syn. n. and Creoleon arenosus (Navás, 1934) syn. n. are new junior synonyms of Creoleon neurasthenicus (Navás, 1913). Creoleon surcoufi (Navás, 1912) syn. n. is a junior synonym of Creoleon cinerascens (Navás, 1912). Ascalaphus hyalinus Navás, 1921 syn. n. is a new junior synonym of Stylascalaphus krueperi (van der Weele, 1909) comb. n. Cueta impar Navás, 1932, Neuroleon gafsanus (Navás, 1921) and Stylascalaphus Sziráki, 1998 taxa were redescribed. The paper contains short characterization of the species in taxonomic, morphologic, habitat and distribution point of view. An annotated checklist of the Moroccan Nemopteridae, Myrmeleontidae, Ascalaphidae fauna was compiled. With 56 figs.
Ephemeral occupancies: Non-linear approach to adaptable architecture
Authors: Lüley Marek
Published: June 2023

When dealing with the daily demands of a sustainable approach in architecture and the rapid development of society, we must accept change and time as an integral part of a building system. An adaptable approach understands architecture as a non-linear process which enables a dynamic response to changing environmental and contextual conditions with the aim to extend the life of a building. The application of adaptability is as ambivalent as the term itself. Therefore, the paper opens a discussion on different perceptions of adaptability in architecture. Adaptability cannot be only understood as moving partitions or vast open spaces. There is a variety of different principles leading to adaptability that can prove the versatility of use - from the basic understanding of flexibility to comprehensive polyvalence. The paper discusses the relationship between capacity and tendency of an architectural space and its components. The discussed relationship is based on actual and virtual properties of an object and their finiteness of interpretation. The paper focuses on non-linear strategies such as a narrative, feed-back and interpretation that could be applied to design to achieve adaptability as part of the proposed strategy called ephemeral occupancies. The manifold of strategies is discussed, and the result of the conceptual analysis is a framework distinguishing non-linear strategy supporting the divergence of capacity and tendency in the context of adaptability.
Innovations in sacral architecture: The resettlement churches of Emil Belluš
Authors: Búliková Lívia
Published: June 2023

The 20th century saw a great breakthrough in architectural innovation; however, this was less evident in sacred buildings. The Evangelical Church of A. C. was inherently innovative, which was also reflected in the architecture of its churches. The innovativeness of the evangelical denomination can be seen in completely new spatial concepts, morphology, the use of new constructions, materials and building technologies, including modern technical equipment of sacral spaces. This article focuses on two buildings by one architect—Emil Belluš (1899-1979), a doyen of Slovak architecture, whose work significantly influenced the field of sacral architecture of the Evangelical Church of A. C. Innovative contributions can first be seen in the design and later in the construction of two evangelical churches in Nesvady and Senec, in Slovakia, built in the 1950s. The churches were part of a project originally intending to build ten new churches for people who had been resettled as part of the government's post-war migration policy. For several decades, these two churches have remained the last addition to sacral buildings constructed in Slovakia. The article deals with the reasons for the creation of church plans, the socio-political situation of that time, circumstances of their construction, and spiritual ideas and creative contribution of the architect Emil Belluš. The research is based on a detailed study of these temples, their layout, and the use of new technologies, construction principles, morphological elements, and other architectural means in which we seek and define an innovative approach to creation.
Seventy Years of FDI Literature: Review, Comparison and Critique
Authors: Siddique Hasinul Hussan , Bardai Barjoyai Bin
Published: June 2023

International capital movement in the form of Foreign Direct Investment (FDI) by multinational enterprises (MNEs) signifies a widely researched phenomenon in comprehensive review of the FDI literature. Its vastness makes it impossible to fathom its depth, as such the paper highlights what the author considers to be mainstream theories in the domain of empirical studies on FDI. This study critically reviews (FDI) literature over a period of 70 years from 1950 to 2020 to provide a theoretical lens for future research beyond the established models. The discussion covers the mode of FDI inflows, statistical methods applied, theoretical models, contributions to paradigms and empirical papers investigating FDI. Furthermore, the papers selected cover heterogenous geographical regions, while in certain papers FDI has been studied as a dependent variable in others as an independent one. The focus lies on the FDI and its resultant activities of MNEs in the form of subsidiaries to carry out market seeking, strategic asset-seeking and efficiency seeking activities. Though, most researchers have narrowed down to four determinants of FDI i.e., motives of MNEs for undertaking FDI, size of MNEs, entry modes into host country and investments sector recently, many works have applied formal theories to provide a framework for market failure such as holdup problems, non-fulfillment of contracts and related agency costs. It is concluded that FDI has evolved into a significant area of empirical investigation. Overall, the gaps and opportunities in existing literature are identified thereby directions for further research emerge.
Solving Finite-Horizon Discounted Non-Stationary MDPS
Authors: Bouchra El Akraoui , Daoui Cherki
Published: June 2023

Research background

Markov Decision Processes (MDPs) are a powerful framework for modeling many real-world problems with finite-horizons that maximize the reward given a sequence of actions. Although many problems such as investment and financial market problems where the value of a reward decreases exponentially with time, require the introduction of interest rates.

Purpose

This study investigates non-stationary finite-horizon MDPs with a discount factor to account for fluctuations in rewards over time.

Research methodology

To consider the fluctuations of rewards with time, the authors define new nonstationary finite-horizon MDPs with a discount factor. First, the existence of an optimal policy for the proposed finite-horizon discounted MDPs is proven. Next, a new Discounted Backward Induction (DBI) algorithm is presented to find it. To enhance the value of their proposal, a financial model is used as an example of a finite-horizon discounted MDP and an adaptive DBI algorithm is used to solve it.

Results

The proposed method calculates the optimal values of the investment to maximize its expected total return with consideration of the time value of money.

Novelty

No existing studies have before examined dynamic finite-horizon problems that account for temporal fluctuations in rewards.
Testing the Validity of Okun’s Law in Algeria: Is there a difference between Maki’s Cointegration and Quantile’s Regression Results?
Authors: Chenini Moussa , Ayad Hicham , Attouchi Manel , Dahmani Mohamed Driouche
Published: June 2023

Research background

This paper examines the existence of Okun’s law in Algeria over the period of 1970–2020 using both the gap and differences model.

Purpose

The main objective of this paper is to econometrically examine, explore and test the nexus among unemployment rate and economic growth, in order to have a clear explanation about unemployment in Algeria.

Research methodology

Firstly, the Kapetanios unit root test and Maki cointegration test are employed for the gap model to deal with the structural breaks than the estimation of the coefficients in this case, secondly, the quantile regression is used for the differences model; finally, three categories of causality tests are used in this research.

Results

The findings revealed that unemployment rates are not affected by output over the period of study both in the gap and differences model. Hence, Okun’s law is not held in Algeria.

Novelty

The study focused on Okun’s law in different ways. This latter carries out structural breaks in both the unit root and co-integration analysis. On the other hand, the study uses the quantile regression for the first time in the examination of Okun’s law. In the same line of thought, this research introduces an asymmetric analysis in the Maki cointegration and quantile regression.
Incidence of Trichothecenes Deoxynivalenol and T-2 Toxin in Poultry Feed Mixtures
Authors: Harčárová Michaela , Naď Pavel
Published: June 2023

Trichothecenes are among the most important fusariotoxins. According to their chemical structure, they are divided into 4 groups (A – D). In terms of agriculture, trichothecenes of groups A and B are of greatest importance. In this study, the incidence of trichothecenes (deoxynivalenol and T-2 toxin) in mixed feed for broilers and turkeys were determined. Deoxynivalenol was detected in all analysed samples of feed mixture for broilers and turkeys (100 %) at an average concentration of 1.776 ppm; 0.675 ppm, respectively. T-2 toxin was present in 93.8 % of mixed feed for broilers at an average concentration of 36.625 ppb and in all of the tested samples (100 %) of turkey mixed feed (average level 25.899 ppb). The trichothecenes deoxynivalenol and T-2 toxin in feed samples for poultry did not exceed concentrations recommended by legislation.
Distribution of Plant-Parasitic Nematodes in Michigan Corn Fields
Authors: Thapa Sita , Darling Elisabeth , Cole Emilie , Poley Kristin , Quintanilla Marisol
Published: June 2023

Plant-parasitic nematodes (PPNs) can cause substantial economic yield losses to many agronomic crops in the United States. A regional-scale survey was completed across 20 counties to determine PPNs prevalence in Michigan corn and how factors such as soil type, tillage, irrigation, and cropping systems influence their distribution. Ten different major genera of PPNs were identified in Michigan corn fields: Longidorus (needle), Helicotylenchus (spiral), Pratylenchus (lesion), Meloidogyne (root-knot), Heterodera (cyst), Hoplolaimus (lance), Tylenchorhynchus or Merlinius (stunt), Paratylenchus (pin), Criconemella (ring), and Xiphinema (dagger). No significant differences among different categories of tillage for lesion, stunt, or needle nematode prevalence was detected. Lesion nematodes were most prevalent in muck soil, while stunt nematode prevalence was significantly affected by the soil type. Needle nematodes were least abundant in irrigated soils and in contrast, stunt nematodes were higher in non-irrigated soils. Spiral nematodes were the most common PPNs in Michigan corn in all cropping systems. These findings will be helpful in planning future nematode studies in Michigan and in developing and evaluating corn nematode management strategies.
Prognostic significance of the biomarker NT-proBNP in the surgical treatment of aortic stenosis (pilot study)
Authors: Kozlov I. A. , Krichevsky L. A. , Rybakov V. Yu.
Published: June 2023

The objective was to study the relationship between the preoperative blood levels of the N-terminal segment of B-type natriuretic peptide precursor (NT-proBNP) and ultrasound and thermodilution indicators of cardiac function before and after on-pump surgery for aortic stenosis, as well as to evaluate the prognostic significance of the biomarker in relation to postoperative myocardial dysfunction.

Materials and methods. The study involved 27 patients aged 57.7±2.5 years who underwent aortic valve replacement. NT-proBNP level was determined before surgery. The indicators of invasive hemodynamics and transesophageal echocardiography were analyzed at stages: I – after anesthesia induction, II – at the end of surgery. Correlation analysis, logistic regression and ROC analysis were used.

Results. The preoperative NT-proBNP level was 2002.0 [540.8–4001.5] pg/ml. At I stage, NT-proBNP correlated with mean pulmonary artery pressure (rho = 0.468; p = 0.014), indices of left ventricular function (rho = –0.509; p = 0.007), end-diastolic and end-systolic volumes (rho = 0.737–0.757; p < 0.0001), as well as ejection fraction (rho = –0.556; p = 0.004) and area contraction fraction (rho = –0.783; p < 0.0001). At II stage, the level of NT-proBNP > 2000 pg/ml was a predictor of the left ventricular area contraction fraction < 50% (OR 1.0011, 95% CI 1.0002–1.0020, p = 0.028, AUC 0.799) , the left ventricular end-systolic area index > 9 cm2/m2 (OR 1.0007, 95% CI 1.0001–1.0013, p = 0.027, AUC 0.886), vasoactive-inotropic score > 10 (OR 1.0006, 95% CI 1.0001–1.0012, p = 0.032, AUC 0.876), duration of sympathomimetic therapy > 24 h (OR 1.0001, 95% CI 1.0000–1.0003, p = 0.049, AUC 0.889).

Conclusions. NT-proBNP blood level was increased in 66.7% of patients with aortic stenosis before surgery. Moreover, the biomarker level directly correlates with the mean pulmonary artery pressure, the indices of end-diastolic and end-systolic volumes, end-diastolic and end-systolic areas of the left ventricle, and it inversely correlates with the left ventricular stroke work index, ejection fraction and left ventricular area contraction fraction. The preoperative NT-proBNP level was a predictor of the postoperative decrease to the pathological level of the ejection fractions and left ventricular area contraction, an increase in the left ventricular end-systolic area index, intensive and prolonged sympathomimetic therapy. Myocardial dysfunctions were most pronounced in patients with biomarker levels above 2000 pg/ml.
RURAL SETTLEMENTS OF THE REGION: PROBLEMS ECONOMIC DEVELOPMENT AND MANAGEMENT
Authors:   Bunin Yelets State University, Shabalina T.A.
Published: June 2023

Rural settlements play a special role in regional development, in the implementation of strategic directions for the territorial location of economic entities. The management of the economic sphere of the territories of rural settlements requires the development and implementation of modern mechanisms and tools to identify "points of growth" for these entities. They will determine the trajectory of strategic development and contribute to improving the quality and standard of living of citizens. Rural self-government bodies play a special role in organizing the effective functioning of territories. Realizing their powers in this area, they are called upon to timely identify emerging problems that impede progressive development, develop, based on their functions and powers, an economic development strategy, based on resource opportunities.
PERSONNEL STRUCTURE OF THE HOTEL COMPANY
Authors:   Volga Region State University of Service, Bogdanova O.A. , Stolpovskikh N.E. ,   Volga Region State University of Service
Published: June 2023

Due to increasing competition in the tourism and hospitality industry, there is a need to study the classical principles of hotel management, which remains relevant today. The aim of this research is to determine the functions of the main departments of a hotel in accordance with the classical representation of its basic structure. The article examines the functionality of hotel staff according to the description of various departments and provides information on units that provide additional services for hotel guests. A description of the main qualities of the staff for providing high-quality service is also presented. The main research method used is modeling, which involves defining the subject of research in an existing model, in this case, the organizational structure of a hotel enterprise. Today, hotel management is a key factor in providing quality hotel services, as well-organized work is the key to successful business.
CORPORATE SOCIAL RESPONSIBILITY AS AN ELEMENT OF THE BUSINESS REPUTATION OF A MODERN ENTERPRISE
Authors:   Bunin Yelets State University, Kostenkova T.A.
Published: June 2023

Modern commercial enterprises achieve success in business not only due to competent financial decisions and marketing policy. The level of profit in recent years has been significantly influenced by the corporate social responsibility program implemented by the company. It allows you to build optimal relationships with business partners, consumers, regional authorities, investors. Due to the external and internal social policy, the company forms a favorable image in the eyes of stakeholders and improves its business reputation. The article discusses various approaches to the term "corporate social responsibility" and clarifies this concept. The significance of the connection of the corporate social responsibility program with the enterprise strategy is substantiated. The analysis of the signs of socially responsible behavior of the organization is carried out and the most significant ones are identified among them. Using the example of the rating of large Russian industrial enterprises, the influence of corporate social responsibility on the business reputation of companies is shown. The advantages that socially responsible companies receive are considered and justified taking into account foreign experience. Priority areas and projects in the field of corporate social responsibility that are relevant for Russian companies are highlighted. Activities and projects in the field of corporate social responsibility are proposed, the implementation of which will have a positive impact on the business reputation of Russian companies and will find support from stakeholders.
Perbandingan gambaran pengetahuan mahasiswa kedokteran dan teknik mesin Universitas Tarumanagara tentang penggunaan alat pelindung diri (APD) COVID-19
Authors: Drajat Radhiyya Tsabitah , Limas Peter Ian
Published: June 2023

Alat Pelindung Diri (APD) merupakan serangkaian peralatan yang digunakan untuk  meminimalisir paparan berbagai macam benda asing. APD digunakan agar menjaga keselamatan dan kesehatan dari para pekerja terutama pada bidang kesehatan.  Oleh karena itu, tingkat pengetahuan terhadap APD pada masa COVID-19 menjadi satu hal yang penting dan perlu diketahui tidak hanya oleh tenaga kesehatan tetapi juga semua personal yang bersinggungan dengan bidang kesehatan. Tujuan dari studi ini untuk mengetahui gambaran tingkat pengetahuan penggunaan APD pada mahasiswa Fakultas Kedokteran dan Fakultas Teknik Mesin Universitas Tarumanagara selama pandemi COVID-19. Metode yang digunakan adalah deskriptif observasional. Pengambilan data responden melalui  kuesioner online selama periode bulan Februari-Juni 2021. Hasil studi didaptakan tingkat pengetahuan penggunaan APD semasa COVID-19 pada 47 mahasiswa Fakultas Kedokteran ialah 13 (27,7%) subjek dalam kategori baik dan 34 (72,3%) subjek dalam kategori cukup cukup, sedangkan pada mahasiswa Fakultas Teknik Mesin didapatkan  tingkat pengetahuan penggunaan APD kategori baik semasa COVID-19  pada 9 (19,1%) subjek, 33 (70,2%) subjek dalam kategori cukup dan 5 (10,7%) subjek memiliki tingkat pengetahuan yang kurang. Mayoritas mahasiswa kedua Fakultas memiliki tingkat penegetahuan yang cukup mengenai penggunaan APD.
Uji fitokimia, kapasitas total antioksidan dan toksisitas ekstrak etanol ubi jalar (Ipomoea batatas (L.) Lam.)
Authors: Leonita Audina , Ferdinal Frans , Limanan David , Yulianti Eny
Published: June 2023

Antioksidan merupakan molekul yang cukup stabil untuk mendonasikan elektronnya ke radikal bebas dan menetralisirkannya, dengan demikian mengurangi kerusakan yang disebabkannya. Salah satu sumber makanan yang mengandung antioksidan adalah ubi jalar (Ipomoea batatas (L.) Lam). Tujuan dari penelitian ini adalah untuk mengetahui kandungan fitokimia, kapasitas total antioksidan dan toksisitas terhadap larva udang Artemia Salina dari ekstrak ubi jalar (Ipomoea batatas (L.) Lam) Penelitian dilakukan berdasarkan studi eksperimental laboratorium dengan bioassay. Sampel penelitian yang digunakan adalah ubi jalar, yang akan diekstraksi menggunakan metode maserasi dengan pelarut etanol. Hasil ekstraksi dilakukan uji fitokimia, uji kapasitas total antioksidan dengan DPPH, dan uji sitotoksisitas dengan BSLT. Hasil uji fitokimia, didapatkan hasil positif untuk alkaloid, betasianin, cardio glikosida, kumarin, flavonoid, fenolik, kuinon, saponin, steroid, terpenoid, dan tannin. Uji kapasitas total antioksidan ekstrak ubi jalar didapatkan IC50 sebesar 585,46 µg/mL dan tergolong antioksidan lemah. Hasil uji toksisitas terhadap larva udang Artemia Salina didapatkan LC50 sebesar 368,69 µg/mL.
Pengaruh pengetahuan tentang dismenorea terhadap penanganannya pada mahasiswi kedokteran Universitas Tarumanagara
Authors: Paramitha Yesan Suci , Hidayat Fadil
Published: June 2023

Pada masa pubertas, menstruasi menjadi tanda kematangan organ seksual. Namun, saat menstruasi biasanya muncul keluhan nyeri yang dapat mengganggu kegiatan sehari-hari (dismenorea). Kejadian dismenorea di Indonesia diperkirakan mencapai 55% di kalangan wanita usia produktif. Pengetahuan mengenai dismenorea pada mahasiswi adalah hal sangat penting sehingga mereka dapat mengetahui dan memiliki perilaku penanganan dismenorea yang baik. Tujuan studi ini untuk mengetahui hubungan antara tingkat pengetahuan terhadap dismenorea dengan perilaku penanganananya. Studi ini bersifat analitik observasional dengan metode cross-sectional.  Pengambilan 194 mahasiswi Kedokteran Universitas Tarumangara angkatan 2020-2022 sebagai subjek studi menggunakan teknik consecutive non-random sampling. Pengambilan data pengetahuan dan penanganan dismenorea menggunakan kuesioner yang telah divalidasi. Data yang didapatkan mayoritas subjek memiliki pengetahuan baik (71,6%) dan perilaku positif terhadap penanganan dismenorea (61,9%). Analisis secara statistik didapatkan hubungan bermakna antara tingkat pengetahuan dengan perilaku penanganan dismenorea (p-value = 0,022 dan 0,046). Mahasiswi yang memiliki tingkat pengetahuan yang baik pada umumnya juga memiliki perilaku penanganan yang positif (nilai PRR = 1,43 dan 1,88).
Hubungan konsumsi minuman kopi terhadap insomnia pada mahasiswa kedokteran Universitas Tarumanagara angkatan 2021-2022
Authors: Prayitno Dondie Dwi , Lontoh Susy Olivia
Published: June 2023

Padatnya jadwal kegiatan dan tugas mahasiswa kedokteran membuat minuman kopi, yang berfungsi sebagai stimulan, sangat digemari. Namun, kafein dalam kopi memiliki efek mempersulit seseorang untuk tertidur ketika dikonsumsi secara berlebihan. Tujuan studi ini untuk mengetahui seberapa besar pengaruh mengonsumsi minuman kopi dengan dengan kejadian insomnia pada mahasiswa kedokteran. Studi analitik observasional ini dilakukan terhadap 110 mahasiswa kedokteran Universitas Tarumanagara angkatan 2021-2022. Pemilihan subjek studi dengan cara consecutive sampling. Instrumen yang digunakan ialah Insomnia Severity Index untuk melihat kejadian insomnia dan kuesioner kebiasaan konsumsi kopi yang terdiri dari 13 pertanyaan. Data antar variabel diuji korelasinya menggunakan chi square. Sebanyak 50 (45,5%) subjek yang mengalami insomnia ringan, 51 (46.4%) subjek mengalami insomnia sedang dan 9 (8.2%) subjek mengalami insomnia berat. Berdasarkan tingkat konsumsi kopi didapatkan 67 (60.9%) subjek termasuk pengonsumsi kopi kategori sedang dan 43 (39.1%) subjek pengonsumsi kopi kategori ringan, namun tidak didapatkan subjek yang memiliki kebiasaan mengonsumsi kopi kategori berat. Hasil studi tidak didapatkan hubungan bermakna secara statistik antara kebiasaan konsumsi kopi dengan kejadian insomnia (p-value 0,334). Namun, subjek yang mengonsumsi kopi kategori sedang 1,459 kali beresiko mengalami insomnia di bandingkan dengan subjek yang mengonsumsi kopi kategori rendah.
GRUPO DE ESTUDOS E AS CONTRIBUIÇÕES NA PRÁTICA DOCENTE
Authors: Cabeleira Marciele Dias Santos , Eberhardt Márcia Rozane , Da Ros Carla Lisiane Paz
Published: June 2023

Os Grupos de Estudos que envolvem docentes, são considerados espaços oportunos de reflexão individual e coletiva acerca da prática pedagógica. Na articulação dos diferentes docentes, a presente escrita traz as primeiras discussões realizadas no Grupo de Estudo Educação e Sustentabilidade – GEES. Esta pesquisa tem por objetivo investigar as contribuições do grupo na prática docente e no planejar de ações pedagógicas desenvolvidas nas escolas municipais e estaduais dos docentes participantes envolvidos. Para isso, utilizamos do relato de experiência reflexivo, baseado nos dados coletados no diário de bordo (PORLÁN; MARTÍN, 2000). Justifica-se que, os encontros aconteceram quinzenalmente via “Google Meet”, na finalidade de dialogar e estudar temáticas relacionadas a sustentabilidade e sua inserção no currículo escolar, além do compartilhar de conhecimentos, a interação dos professores atuantes na Educação Básica, no intuito de estimular a reflexão crítica de forma a colaborar construtivamente no desenvolver da práxis docente. Os resultados dos encontros nos mostram que o GEES é um espaço significativo para as discussões e planejamento de práticas pedagógicas que contribuem para o desenvolvimento da sustentabilidade no currículo escolar, bem como, ampliar as possibilidades de reflexão da práxis docente, contribuindo de forma pertinente na reconstrução profissional. Em suma, o GEES pode se caracterizar como uma forma de formação continuada, que apresentam inúmeras possibilidades de (re)constituição de saberes e construção de novas práticas pedagógicas, a partir do diálogo construtivo e empático, um espaço que contribui positivamente para o crescimento intelectual e profissional dos docentes.
Existential Truth in Dialectical-symbolic Understanding
Authors: Fedorov Sergei
Published: June 2023

The subject of research in this article is the phenomenon of existential truth. The author relies on the distinction between epistemic and existential truth proposed by D.V. Pivovarov. The latter is the correspondence of knowledge (or being in the case of ontological truth) to the subject-object unity, human being, which is the basis of cognitive activity. The ideas related to the existential understanding of truth in the works of B. Pascal, S. Kierkegaard, M. Unamuno, H. Ortega y Gasset, L. Shestov, N.A. Berdyaev, K. Jaspers, G. Marcel, A. Camus, J.-P. Sartre and M. Heidegger are presented. "Cordiality", subjectivity, vitality, perspectivism, irrationality, creative nature, communication, personality, "rebellion", freedom, "non-concealment" of existential truth are highlighted. With the help of A.F. Losev's dialectical methodology, an attempt is made to comprehend these signs as moments of symbolism of existential truth.   The mainstay is the works of A.F. Losev, in which the symbol is understood as a communicative and interpretive expression of a transcendent essence ("the very self"). This expression is a "directly-intuitively" given generality, naturally decomposed into a number of separate singularities, which can be realized in reality and thereby become a "myth" in Losev's understanding. The myth, immanent to personal existence, is intensively experienced by a person, manifests itself in an irrational "miracle". The symbol and myth reveal the considered signs of existential truth and at the same time take into account the objective, functional sides of the truth. From the point of view of the dialectical-symbolic approach, existential truth is the correspondence of knowledge (or being) to a dialectically concrete symbolic reflection of reality, subject-object unity, which is a "directly intuitive" given in immanent personal being. The novelty of the work lies in the application of A.F. Losev's dialectical theory of the symbol to the study of the existential understanding of truth.
Effectiveness of Antenatal Health Education via Mobile Phone Calls Among Women Seeking Antenatal Care Services in Kisii County, Kenya
Authors: Malachi Zillah M. , Kivuti-Bitok Lucy W. , Karani Anna K. , Cheptum Joyce J.
Published: June 2023

Knowledge of antenatal care is important in reducing maternal mortality and morbidity. Mobile phones have demonstrated an increase in the use of antenatal care services. However, few studies have indicated the effectiveness of health education on antenatal care via mobile phone calls. In this study, we aimed to evaluate the effectiveness of health education on antenatal care provided through mobile phone calls among pregnant women in Kisii County, Kenya. A total of 160 pregnant women up to 26 weeks of gestation were recruited for the study from 16 sub-county health facilities (clusters) in Kisii County. The women were enrolled in their first visit and followed up until delivery. The sub-county health facilities were randomly assigned to either intervention or control arms. The intervention involved giving health education on antenatal care through mobile phone calls. All the participants in both study arms received routine antenatal care. However, those enrolled in the intervention sites additionally received health education through mobile phone calls. The primary outcome measure was antenatal care knowledge scores. Baseline and end-of-study questionnaires were used to collect data. Women in the intervention group scored highly in antenatal care knowledge post-intervention as compared to those in the control group, 7.87 (SE of the difference = 0.68, p-value < 0.001, 95% CI (6.53–9.20). Health education delivered through mobile phone calls has great potential in improving antenatal care knowledge.
Unnatural endo type-B PPAPs as novel compounds with activity against Mycobacterium tuberculosis.
Authors: Peslalz Philipp , Grieshober Mark , Kraus Frank , Bleisch Anton , Izzo Flavia , Lichtenstein Dajana , Hammer Helen , Vorbach Andreas , Momoi Kyoko , Zanger Ulrich , Brötz-Oesterhelt Heike , Braeuning Albert , Stenger Steffen , Plietker Bernd
Published: June 2023

Before the emergence of SARS-CoV-2, tuberculosis (TB) was the leading cause of infectious disease mortality worldwide. Like all antibiotic-exposed bacteria Mycobacterium tuberculosis (Mtb) developed multidrug-resistant (MDR) and exten-sively drug-resistant (XDR) strains which require new antibiotics with novel mechanism of actions. Hyperforin, a natural type-A polyprenylated polycyclic acylphloroglucinol (PPAP) isolated from St. John’s wort, is known for its antibacterial, antidepressant and antimycobacterial activity. However, hyperforin is not stable and easily degradable in light, heat it and oxidizes. Here we report photo- and benchstable type-B PPAPs with structural similarity to hyperforin and enhanced an-timycobacterial activity. We tested a panel of PPAPs and identified our previously reported molecule PPAP22 as lead compound. Converting PPAP22 into the corresponding sodium salt, PPAP53, enhanced the solubility dramatically. We show that PPAP53 inhibits the growth of virulent, extracellular Mtb. Strikingly, the activity is more pronounced intracel-lular Mtb residing in human primary macrophages without damaging the host cell or lung cells. Importantly PPAP53 was also highly active against drug-resistant Mtb. Additionally, we analysed the in vitro properties of PPAP53 in terms of CYP-induction and PXR interaction. Taken together we introduce type-B PPAPs are a new class of antimycobacterial com-pounds, with remarkable activity and favorouble physical properties.
Empowering extra fuel supply in E. coli by electron bifurcation for robust H2, ATP and succinate production
Authors: Intasian Pattarawan , Sutthaphirom Chalermroj , Binlaeh Asweena , Phonbuppha Jittima , Jaroensuk Juthamas , Teanphonkrang Somjai , Woraruthai Thamonwan , Tirapanampai Charndanai , Onchan Warunya , Schulte Albert , Buckel Wolfgang , Weeranoppanant Nopphon , Wongnate Thanyaporn , Sucharitakul Jeerus , Chaiyen Pimchai
Published: June 2023

Microbial production of hydrogen (future ideal fuel and important gas for industries) under anoxic conditions has limited ATP availability and low efficiency. We engineered E. coli K12 to acquire a flavin-based electron bifurcation (FBEB) system, a bioenergetic route typically found in strict anaerobes, which uses NADH to generate low potential reduced ferredoxin and high potential butyryl-CoA. The oxygen-tolerant FBEB-E. coli showed higher H2 and succinate production (2-4 folds), lower cellular reduction potentials, greater accumulation of cellular reductants and various metabolites, including ATP (up to a 7-fold increase). It could better tolerate prolonged and recycled usage of the engineered cell for H2 and succinate production than the native strain. FBEB-E. coli could also use various substrates such as formate, D-glucose and food waste for H2 and succinate production. This is a promising pathway to sustainable H2 and succinate production. This work also demonstrates that E. coli with an extra electron bifurcation system is a robust synthetic biology host.
Electrophile Scanning Reveals Reactivity Hotspots for the Design of Covalent Peptide Binders
Authors: Grob Nathalie M. , Remarcik Clint , Rössler Simon L. , Wong Jeffrey Y. K. , Wang John C. K. , Tao Jason , Smith Corey L. , Loas Andrei , Buchwald Stephen L. , Eaton Dan L. , Preciado López Magdalena , Pentelute Bradley L.
Published: June 2023

Protein–protein interactions (PPIs) are intriguing targets in drug discovery and development. Peptides are well suited to target PPIs, which typically present with large surface areas lacking distinct features and deep binding pockets. To improve binding interactions to these topologies by PPI-focused therapeutics and advance their development, potential ligands can be equipped with electrophilic groups to enable binding through covalent mechanisms of action. We report a strategy termed electrophile scanning to identify reactivity hotspots in a known peptide ligand. Cysteine mutants of the ligand are used to install protein-reactive modifiers via a palladium oxidative addition complex (Pd-OAC). Reactivity hotspots are revealed by cross-linking reactions with the target protein under physiological conditions. In a system with the 9-mer peptide antigen VL9 and MHC class I receptor HLA-E, we identify two reactivity hotspots that afford up to 87% conversion to the protein–peptide conjugate within 4 hours. The reactions are specific to the target protein in vitro and dependent on the peptide sequence. Moreover, the cross-linked peptide successfully inhibits molecular recognition of HLA-E by CD94─NKG2A possibly due to structural changes enacted at the PPI interface. The results illustrate the potential of electrophile scanning as a tool for rapid discovery and development of covalent peptide binders.
Otra mirada a la catedral: a 50 años de “Property rules, liability rules and inalienability: one view of the cathedral”
Authors: Saavedra Velazco Renzo Esteban
Published: June 2023

En abril de 1972, Guido Calabresi y Douglas Melamed publicaron un artículo que es aclamado unánimemente como un hito en la comprensión del sistema jurídico. En dicho trabajo, los autores identificaron tres reglas que disciplinan las titularidades legales, las así llamadas reglas de propiedad, reglas de responsabilidad e inalienabilidad. La diferencia entre ellas guarda relación con la manera en que permiten el ejercicio, disposición y tutela de las prerrogativas jurídicas. A pesar de la trascendencia del enfoque, el tiempo transcurrido desde su publicación y la difusión alcanzada a nivel global por el movimiento de Derecho y Economía, en los países del Civil Law —sobre todo latinoamericanos— no se ha valorado en sus reales alcances la propuesta, ni se ha tomado contacto con las posteriores precisiones y críticas. El propósito de la presente investigación es llevar las ideas de Calabresi y Melamed más allá a fin de vislumbrar su utilidad para la comprensión del derecho, convirtiéndose así en un tópico de teoría general del derecho.
Aspectos legales de la tecnología Blockchain
Authors: Morales Cáceres Alejandro Rafael
Published: June 2023

La Blockchain ha irrumpido en años recientes como una tecnología que promete revolucionar la forma como llevan a cabo las transacciones a nivel global. En tal sentido, por medio del presente artículo el autor realiza una aproximación sobre lo que es la Blockchain, cómo esta es un medio que ha favorecido el auge de las criptomonedas —que no requieren de un banco intermediario para efectuar pagos a través de internet—, la aparición de los smart contracts que operan automáticamente para regular los negocios efectuados por medios virtuales, pasando por explicar en qué consiste la tokenización de activos —tangibles o intangibles— para su posterior comercialización empleando la Blockchain, así como reflexionando sobre la incorporación de estas innovaciones en el ordenamiento jurídico nacional.
El nuevo lujo y el Luxury Law: una mirada al presente y futuro
Authors: Fasson Llosa Annalucía
Published: June 2023

El luxury law o derecho del lujo es una nueva especialización del derecho que consiste en asesorar a todas las empresas que se dedican, en sus diferentes, categorías al sector económico del lujo. Asimismo, en este artículo explicaremos en qué consiste el nuevo lujo y cómo el derecho se encuentra contribuyendo en su desarrollo a través del uso de la tecnología y la sostenibilidad.
La equidad de género como parte de la responsabilidad social de las empresas
Authors: Pita Dueñas Bárbara
Published: June 2023

Nuestra sociedad en la búsqueda de un mundo con grandes objetivos ha logrado efectuar considerables avances para el reconocimiento y respeto de la dignidad humana. Así como, el desarrollo integral de las mismas. En ese sentido, se ha encontrado en las empresas un aliado para el logro de este objetivo. Las empresas constituyen un fuerte instrumento de desarrollo económico y social de los países, así como para el fomento de la equidad de género, y ello se conoce como responsabilidad social que es el tema que abordaremos en el presente trabajo.
Sistem Pakar Identifikasi Penyakit Kambing Jawa Menggunakan Metode Forward Chaining
Authors: Kusumantomo Sri Muhammad , Akbar Mutaqin
Published: June 2023

Hewan kambing dalam bisnis peternakan yakni zona bisnis yang bisa dikatakan menjanjikan. Kambing jawa misalnya, kambing tipe jawa memiliki harga yang sangat mahal dari anak kambing jawa sampai kambing jawa yang telah berusia. Bisnis ternak kambing jawa memanglah sangat menguntungkan, tetapi bisnis ini bukan tanpa hambatan. Begitu banyak hambatan yang ditemui oleh para peternak khususnta yang bertempat tinggal di desa yang jauh dengan rumah sakit hewan. Sehingga, dipilihnya metode identifikasi penyakit kambing jawa ini sebab tanda-tanda penyakit yang umum dialami oleh kambing jawa relatif gampang buat diamati serta nyaman dicoba oleh siapapun. Aplikasi yang dibentuk dilengkapi dengan sistem pengelolaan pengetahuan yang gampang digunakan serta dinamis. Maksudnya jika pakar sanggup meningkatkan, mengganti, serta menghapus pengetahuan ataupun ketentuan baru tanpa wajib mengawali dari awal. Aplikasi dikembangkan dengan memakai bahasa pemrograman PHP serta MySQL selaku basis informasi. Tata cara inferensi yang digunakan merupakan forward chaining, ialah proses inferensi yang mengawali pencarian dari premis ataupun informasi masukan berbentuk indikasi mengarah pada konklusi ialah kesimpulan penyakit yang dialami dan membagikan pemecahan mengenai anjuran penyembuhan serta penangkalan bersumber pada tanda-tanda yang diamati.dalam riset ini diperoleh hasil 100% kesesuaian antara hasil identifikasi dari ahli dengan identifikasi dari aplikasi.
Sistem Pakar Diagnosa Penyakit Tanaman Bunga Kertas Zinnia Menggunakan Metode Certainty Factor
Authors: Triatmi Nanik , Akbar Mutaqin
Published: June 2023

Bunga kertas atau bunga Zinnia adalah tumbuhan semusim miliki Genus Zinnia. Bunga ini berasal dari negara Meksiko, tumbuh sebagai tanaman hias yang tersebar diberbagai  belahan dunia, termasuk di wilayah Indonesia. Bunga kertas zinnia sangat terbilang sangat populer di Indonesia, tanaman ini sering digunakan untuk tanaman hias. Namun dalam perawatan tanaman terkadang petani tanaman hias mengalami beberapa kendala akibat penyakit maupun hama tanaman yang menyerang karena masih minim pengetahuan maupun penanganan tentang tanaman tersebut. Karena jika tanaman tidak ditangani dengan cepat akan membuat petani mengalami kerugian. Tujuan membangun sistem pakar diagnosa penyakit tanaman bunga kertas zinnia, dengan adanya sistem pakar tersebut dapat lebih efektif untuk membantu petani dalam menangani penyakit atau hama yang menyerang. Proses inferensi menggunakan metode certainty factor, mencari data gejala lalu memilih parameter sesuai kondisi yang ada, kemudian diproses dengan hasil diagnosa berupa jenis penyakit, hasil persentase, detail penyakit dan saran. Berdasarkan 18 gejala dan 5 jenis penyakit, didapatkan 25 data pengujian sistem, 20 data hasilnya sesuai dan 5 data  hasilnya tidak cocok sehingga hasil persentase rata-rata  sebesar 80%.