bluuebunny/crossref_metadata_2025 huggingface dataset:
Genome‐wide detection of changes in allelic frequency in Landrace pigs selected for resistance to mycoplasma pneumonia of swine
Authors: Uemoto Yoshinobu , Ichinoseki Kasumi , Matsumoto Toshimi , Oka Nozomi , Takamori Hironori , Kadowaki Hiroshi , Shibata Chihiro , Suzuki Eisaku , Okamura Toshihiro , Aso Hisashi , Kitazawa Haruki , Satoh Masahiro , Uenishi Hirohide , Suzuki Keiichi
Published: March 2023

Closed‐pig line breeding could change the genetic structure at a genome‐wide scale because of the selection in a pig breeding population. We investigated the changes in population structure among generations at a genome‐wide scale and the selected loci across the genome by comparing the observed and expected allele frequency changes in mycoplasma pneumonia of swine (MPS)‐selected pigs. Eight hundred and seventy‐four Landrace pigs, selected for MPS resistance without reducing average daily gain over five generations, had 37,299 single nucleotide polymorphisms (SNPs) and were used for genomic analyses. Regarding population structure, individuals in the first generation were the most widely distributed and then converged into a specific group, as they were selected over five generations. For allele frequency changes, 96 and 14 SNPs had higher allele frequency changes than the 99.9% and 99.99% thresholds of the expected changes, respectively. These SNPs were evenly spread across the genome, and a few of these selected regions overlapped with previously detected quantitative trait loci for MPS and immune‐related traits. Our results indicated that the considerable changes in allele frequency were identified in many regions across the genome by closed‐pig line breeding based on estimated breeding value.
Indicators of contact visit quality in non‐kinship foster care: An observational checklist
Authors: García‐Martín Miguel A. , Bernedo Isabel M. , Salas María D. , González‐Pasarín Lucía
Published: March 2023

This study explores whether the frequency and diversity of behaviours observed during contact visits may be used as indicators of visit quality. We observed 20 contact visits and quantified the frequency and diversity of behaviours for both parent and child, classified as positive or negative with respect to the child's well‐being. Quality of visits was classified based on a list of parent and child behaviours and two indicators (diversity and frequency), to create two observational checklists and calculate an overall quality index. This observational tool will enable identification of areas where birth parents or their child require additional support.
The effectiveness and cost efficiency of different predator exclosure designs to increase piping plover (Charadrius melodus) nest success and fledging rate in Alberta, Canada
Authors: Peters Susan H. , Engley Lance , Rezansoff Amanda , Prescott David R. C. , Jones Paul F.
Published: March 2023

An estimated 30% of the North American piping plover (Charadrius melodus)breeding population occurs in Canada, where it isEndangered. Predator exclosures are a common management tool across the species' range to increase nest success. Using data from 1998 to 2010 on 820 nests, collected as part of an ongoing management program in Alberta, we compare daily nest survival (DNS), numbers of chicks hatched and fledglings produced, and cost/chick among three treatments (large, medium, small exclosures) and natural nests. During the early period (1998–2001), when all three types of exclosures were applied, there were no significant differences in DNS between exclosed nests and natural nests. During the late period (2002–2010), when only small exclosures were applied, nests with small exclosures had a significantly higher DNS rate ( = 0.994,n = 594) compared with natural nests ( = 0.984,n = 88). Nests with small exclosures also hatched more chicks ( = 3.21,n = 598) and produced more fledglings ( = 1.17,n = 337) than natural nests ( = 1.73 chicks,n = 31;  = 0.59 fledglings,n = 21) during the late period. However, considering only successful nests, the differences were not significant for either period, indicating no added benefit of exclosures beyond protecting the nest. The cost/chick rate was lowest using small exclosures (cylindrical, 40 by 60 cm), and this portable design is well‐suited for widespread application in the field. We demonstrate increased DNS for nests with small exclosures and a mean fledging rate close to the goal of 1.25 chicks/nest/year, although this did not increase Alberta's piping plover population beyond the timeframe of systematic exclosure application. Long‐term, cost‐efficient management tools that increase nest success and fledging rates should continue.
Intellectual property and the organization of the global value chain
Authors: Bolatto Stefano , Naghavi Alireza , Ottaviano Gianmarco , Zajc Kejžar Katja
Published: March 2023

This paper highlights the role of intangible assets in a property rights model of firm organization with sequential production. Empirical evidence based on foreign direct investment and transaction‐level trade data of Slovenian firms reveals that the strength of intellectual property rights (IPR) protection in the supplier's location affects firms' organizational choices whenever supplier investments are sequential complements. In this case, when a firm must transmit know‐how to each supplier, and more knowledge is accrued as production moves downstream, better IPR institutions lead to lower incidence of vertical integration over outsourcing, principally at more downstream stages. On the other hand, the organizational choice is far less responsive to IPR protection for sequential substitutes. Moreover, we show that improving IPR and contracting institutions (e.g. rule of law) may have the opposite effect on firm boundaries. Our findings conform with a property rights model in which the quality of the IPR regime governs knowledge transmission along the supply chain, ultimately driving firm organization through the suppliers' incentive structure.
Divergent cognitive trajectories in early stage Huntington's disease: A 3‐year longitudinal study
Authors: Martínez‐Horta Saul , Perez‐Perez Jesús , Oltra‐Cucarella Javier , Sampedro Frederic , Horta‐Barba Andrea , Puig‐Davi Arnau , Pagonabarraga Javier , Kulisevsky Jaime
Published: March 2023

Background and purpose

Cognitive impairment is a central feature of Huntington's disease (HD), but it is unclear to what extent more aggressive cognitive phenotypes exist in HD among individuals with the same genetic load and equivalence in other clinical and sociodemographic variables.

Methods

We included Enroll‐HD study participants in early and early–mid stages of HD at baseline and with three consecutive yearly follow‐ups for whom several clinical and sociodemographic as well as cognitive measures were recorded. We excluded participants with low and large CAG repeat length (CAG < 39 & > 55), with juvenile or late onset HD, and with dementia at baseline. We explored the existence of different groups according to the profile of cognitive progression using a two‐step k‐means cluster analysis model based on the combination of different cognitive outcomes.

Results

We identified a slow cognitive progression group of 293 participants and an aggressive progression group (F‐CogHD) of 235 for which there were no differences at the baseline visit in any of the measures explored, with the exception of a slightly higher motor score in the F‐CogHD group. This group showed a more pronounced annual loss of functionality and a more marked motor and psychiatric deterioration.

Conclusions

The rate of progression of cognitive deterioration in HD is strongly variable even between patients sharing, among other variables, equivalent CAG repeat length, age, and disease duration. We can recognize at least two phenotypes that differ in terms of rate of progression. Our findings open new avenues to study additional mechanisms contributing to HD heterogeneity.
Dermatomyositis autoantigen CHD4 forms immune stimulatory complexes with endogenous DNA
Authors: Guel Tugce , Scholtissek Benedikt , Siegl Julia , Fetter Tanja , Mayer Günter , Bieber Thomas , Wenzel Joerg
Published: March 2023

Dermatomyositis (DM) is an idiopathic inflammatory myopathy belonging to the spectrum of autoimmune connective tissue diseases. DM patients present with antinuclear antibodies against Mi‐2, also known as Chromodomain‐helicase‐DNA‐binding protein 4 (CHD4). CHD4 is upregulated in DM skin biopsies and could potentially affect DM pathophysiology as it binds endogenous DNA with a high affinity (KD = 0.2 nM ± 0.076 nM) and forms CHD4‐DNA complexes. The complexes are localized in the cytoplasm of UV‐radiated and transfected HaCaTs and amplify the expression of interferon (IFN) regulated genes and the amount of functional CXCL10 protein stronger than DNA alone. The enhancement of the type I IFN pathway activation in HaCaTs through CHD4‐DNA signalling suggests a possible mechanism for the sustainment of the pro‐inflammatory vicious cycle in DM skin lesions.
Availability of palliative parenteral nutrition to patients with advanced cancer: A national survey of service provision
Authors: Baker James , Smith Philip J. , White Simon J. , Gifford Alison J.
Published: March 2023

Background

Patients with advanced malignancy who are unable to meet their nutritional requirements orally or enterally as a result of intestinal failure may be considered for parenteral nutrition support. Current UK guidance recommends that patients with a 3‐month prognosis and good performance status (i.e., Karnofsky performance status >50) should be considered for this intervention at home (termed Home Parenteral Nutrition; HPN). However, HPN is a nationally commissioned service by National Health Service (NHS) England and Improvement that can only be initiated at specific NHS centres and so may not be easily accessed by patients outside of these centres. This survey aimed to identify current clinical practice across UK hospitals about how palliative parenteral nutrition is initiated.

Methods

Clinical staff associated with Nutrition Support Teams at NHS Organisations within the UK were invited to complete an electronically administered survey of national clinical practice through advertisements posted on relevant professional interest groups.

Results

Sixty clinicians responded to the survey administered between September and November 2020. The majority of respondents responded positively that decisions made to initiate palliative parenteral nutrition were conducted in alignment with current national guidance in relation to decision‐making and formulation of parenteral nutrition. Variation was observed in relation to the provision of advance care planning in relation to nutrition support prior to discharge, as well as the consideration of venting gastrostomy placement in patients with malignant bowel obstruction unsuitable for surgical intervention.

Conclusions

Adherence to current national guidance in relation to the provision of palliative parenteral nutrition is variable for some aspects of care. Further work is required particularly in relation to maximising the opportunity for the provision of advance care planning prior to discharge in this patient cohort.
Esthetic considerations for treating the patient of European descent: Thriving in diversity international roundtable series
Authors: Fabi Sabrina G. , Casabona Gabriela , Ogilvie Patricia , Acquilla Raj , Dayan Steve
Published: March 2023

Background

The European esthetic experience is informative for understanding both innovation as well as how to care for patients of various backgrounds and ages.

Aims

To discuss best practices for treating the European population and how these approaches may be applied to patient populations across the globe.

Patients/Methods

In support of clinicians who wish to serve a diverse patient population, a 6‐part, international roundtable series focused on diversity in esthetics was conducted from August 24, 2021 to May 16,2022. In each roundtable, expert clinicians were invited to contribute and share best practices.

Results

The results of the fifth roundtable in the series, the European Patient, are described here. Key ideas include the growing number of people over the age of 65 years in Europe and the management of this more mature patient population; the role of functional anatomy in treating patients with both fillers and botulinum toxin; and the role of ultrasound in clinical practice for mapping vasculature.

Conclusions

While there is no typical European face, there is much to be learned from thoughtful consideration of how to best manage more mature patients as well as how to use minimally invasive modalities, such as injectables, efficiently to achieve natural‐looking results.
Nurses and nature; Does green space make a difference?
Authors: Middleton Rebekkah , Astell‐Burt Thomas
Published: March 2023

How we engage in and with nature is of growing interest in relation to our health and well‐being. For nurses with stressful workloads that are contributing to fatigue, psychological burden, insomnia, and decreased coping strategies, interactions with nature or green space are essential as it has been demonstrated to facilitate better environments and outcomes for nurses. Evidence of the impact of nature is limited. However, the value of interactions with nature has been prioritised by the World Health Organization and so healthcare organizations should be considering overt and practical ways to ensure nurses, and other healthcare providers, are exposed to nature to contribute towards healthier environments.
“OK guys, thank you for coming today”: Indexicality, utterance events, and verbal rituals in political speeches in Sheikh Jarrah
Authors: Noy Chaim
Published: March 2023

This ethnography looks at the indexical function of several brief utterances, routinely employed by a Palestinian speechmaker, in the Sheikh Jarrah protest in East Jerusalem. Following Silverstein's contributions to the indexically based theory of (meta)pragmatics, “creative” and nonreferential utterances are examined at the utterance event level, in relation to the speech event level, and more generally to verbal rituals. The political speeches I study have been delivered weekly, in Hebrew, by a Sheikh Jarrah resident and activist, for over a decade. The ethnographic analysis depicts how the utterances create a physical and symbolic (rhetorical) space for the performance of the speeches, routinize and ritualize their recurrence, and secure their endurance in a hostile environment. This is accomplished by spatially disassembling and reassembling the protesters, modifying the participation structure, and establishing a host–guest relationship. The speaker is repositioned as a resident, activist, and political rhetor‐in‐the‐becoming, and the protestors are repositioned as his audience.
Board gender diversity, feminine culture, and innovation for environmental sustainability
Authors: Bazel‐Shoham Ofra , Lee Sang Mook , Munjal Surender , Shoham Amir
Published: March 2023

The environmental crisis is one of global society's most extreme grand challenges. One of the supply‐side factors that can help cope with it is corporate environmental innovation. Based on the upper echelon and value belief theory and with significant empirical analyses, our results strongly support that the presence of women on the board positively impacts innovation aimed at environmental sustainability. The results are based on a sample of 19,800 firm‐year observations of 2966 unique firms in 54 industry groups domiciled in 52 countries for the 2003–2019 period. The global distribution of the firms means that the sample is diverse enough to examine our main hypotheses. In addition, we show that culturally masculine societies, as captured by their grammatical gender marking, have a negative impact on such innovation. The masculine culture also moderates the impact of gender board diversity on innovation for environmental sustainability. Our results are robust to a battery of empirical tests and definitions, including instrumental variable approach and propensity score matching causality tests. We further explored firms' attitudes toward innovation for environmental sustainability by adding a qualitative case study research design to our quantitative analysis. That was based on semi‐structured interviews with board members and executives. The case studies provided additional support to the results in the quantitative analysis part. This study's empirical results have various broad theoretical and practical implications for board composition, taking into account the linguistic environment of the firm.
Cotton 4‐coumarate‐CoA ligase 3 enhanced plant resistance to Verticillium dahliae by promoting jasmonic acid signaling‐mediated vascular lignification and metabolic flux
Authors: Alariqi Muna , Ramadan Mohamed , Wang Qiongqiong , Yang Zhaoguang , Hui Xi , Nie Xinhui , Ahmed Amani , Chen Qiansi , Wang Yanyin , Zhu Longfu , Zhang Xianlong , Jin Shuangxia
Published: March 2023

Lignins and their antimicrobial‐related polymers cooperatively enhance plant resistance to pathogens. Several isoforms of 4‐coumarate‐coenzyme A ligases (4CLs) have been identified as indispensable enzymes involved in lignin and flavonoid biosynthetic pathways. However, their roles in plant–pathogen interaction are still poorly understood. This study uncovers the role of Gh4CL3 in cotton resistance to the vascular pathogen Verticillium dahliae. The cotton 4CL3‐CRISPR/Cas9 mutant (CR4cl) exhibited high susceptibility to V. dahliae. This susceptibility was most probably due to the reduction in the total lignin content and the biosynthesis of several phenolic metabolites, e.g., rutin, catechin, scopoletin glucoside, and chlorogenic acid, along with jasmonic acid (JA) attenuation. These changes were coupled with a significant reduction in 4CL activity toward p‐coumaric acid substrate, and it is likely that recombinant Gh4CL3 could specifically catalyze p‐coumaric acid to form p‐coumaroyl‐coenzyme A. Thus, overexpression of Gh4CL3 (OE4CL) showed increasing 4CL activity that augmented phenolic precursors, cinnamic, p‐coumaric, and sinapic acids, channeling into lignin and flavonoid biosyntheses and enhanced resistance to V. dahliae. Besides, Gh4CL3 overexpression activated JA signaling that instantly stimulated lignin deposition and metabolic flux in response to pathogen, which all established an efficient plant defense response system, and inhibited V. dahliae mycelium growth. Our results propose that Gh4CL3 acts as a positive regulator for cotton resistance against V. dahliae by promoting JA signaling‐mediated enhanced cell wall rigidity and metabolic flux.
A deductive thematic analysis of nurses with job‐related problems who completed suicide during the early COVID‐19 pandemic: A preliminary report
Authors: James Kristina E. , Agarwal Suzanne , Armenion Karen L. , Clapp Chris , Barnes Arianna , Ye Gordon Y. , Zisook Sidney , Davidson Judy E.
Published: March 2023

Background

Prior to the novel coronavirus (COVID‐19) pandemic, nurses died by suicide more frequently than the general population. Antecedents prior to death include known job problems, such as disciplinary action; diversion of medications; inability to work due to chronic pain; and physical and mental illness.

Aim

The aim of this study was to explore the suicide experience of nurses who died with known job‐related problems during the early phase of the COVID‐19 pandemic compared to what has been previously described.

Method

Deductive reflexive thematic analysis was used to analyze narratives of nurses with known job problems who died by suicide from the Centers for Disease Control and Prevention's National Violent Death Reporting System.

Results

Forty‐three nurses with known job‐related problems completed suicide between March and December 2020. Factors associated with death were similar to previous findings with notable exceptions, increased prevalence of suicidal ideation and post‐traumatic stress prior to the event. Pandemic‐specific issues were noted including reduction in hours, fear of disease transmission, civil unrest, and grief‐related trauma.

Linking Evidence to Action

Suicide prevention programs need to address both institutional and individual factors associated with nurse suicide. As previously recommended, transitions into retirement and job loss are vulnerable times warranting psychological support. Further, strategies to reduce the impact of stressors and increase support for nurses are needed at the organizational level. A systems level approach to hardwire coping strategies is indicated pre‐licensure and throughout nurses' careers. A new focus on how to process personal and professional grief is warranted. Resources are needed for nurses traumatized by life (rape, childhood trauma) or work‐related experiences.
Extended Analysis of HIV Infection in Cisgender Men and Transgender Women Who Have Sex with Men Receiving Injectable Cabotegravir for HIV Prevention: HPTN 083
Authors: Marzinke Mark A. , Fogel Jessica M. , Wang Zhe , Piwowar-Manning Estelle , Kofron Ryan , Moser Amber , Bhandari Pradip , Gollings Ryann , Bushman Lane R. , Weng Lei , Halvas Elias K. , Mellors John , Anderson Peter L. , Persaud Deborah , Hendrix Craig W. , McCauley Marybeth , Rinehart Alex R. , St Clair Marty , Ford Susan L. , Rooney James F. , Adeyeye Adeola , Chariyalertsak Suwat , Mayer Kenneth , Arduino Roberto C. , Cohen Myron S. , Grinsztejn Beatriz , Hanscom Brett , Landovitz Raphael J. , Eshleman Susan H.
Published: March 2023

HPTN 083 demonstrated that injectable cabotegravir (CAB) was superior to oral tenofovir disoproxil fumarate-emtricitabine (TDF-FTC) for HIV prevention in cisgender men and transgender women who have sex with men. We previously analyzed 58 infections in the blinded phase of HPTN 083 (16 in the CAB arm and 42 in the TDF-FTC arm).
Increasing Student Confidence in Writing: Integrating Authentic Manuscript Writing into an Online 8-Week Research Program
Authors: Kim Choah , Preston Kiam , Braga Alice , Fankhauser Sarah C.
Published: March 2023

In various formats, students at the secondary and postsecondary levels participate in multiweek authentic science research projects. There have been many papers explaining the operations of such programs, but few have provided explicit instruction on how to incorporate authentic communication practices into the student research process.
Complete Genome Sequence of Aeromonas hydrophila Strain Y-S01, Isolated from Diseased Dark Sleeper (Odontobutis potamophila) in China
Authors: Zhao YanHua , Zhang ShiYong , Liu HongYan , Liu Guoxing
Published: March 2023

Aeromonas hydrophila
is one of the most important pathogenic bacteria for aquaculture animals, such as fish and crustaceans. In this study, we isolated a pathogenic bacterial strain, named Y-SC01, from dark sleeper (
Odontobutis potamophila
) with rotten gills; the strain was identified as
A. hydrophila
by physiological and biochemical tests.
Microbial Species-Area Relationships on the Skins of Amphibian Hosts
Authors: Yang Fan , Liu Zhidong , Zhou Jin , Guo Xuecheng , Chen Youhua
Published: March 2023

In this study, we investigate species-area relationships (SARs) for skin-borne symbiotic microbes of wildlife hosts. Unlike the traditional SARs for plants and animals, symbiotic microbial SARs were complex.
Protein Disulfide Isomerase and Extracellular Adherence Protein Cooperatively Potentiate Staphylococcal Invasion into Endothelial Cells
Authors: Leidecker Marleen , Bertling Anne , Hussain Muzaffar , Bischoff Markus , Eble Johannes A. , Fender Anke C. , Jurk Kerstin , Rumpf Christine , Herrmann Mathias , Kehrel Beate E. , Niemann Silke
Published: March 2023

Staphylococcus aureus
can invade and persist in non-professional phagocytes, thereby escaping host defense mechanisms and antibiotic treatment. The intracellular lifestyle of
S. aureus
contributes to the development of infection, e.g., in infective endocarditis or chronic osteomyelitis.
Assessing maternal alcohol consumption in pregnancy: comparison of confidential postnatal maternal interview and measurement of alcohol biomarkers in meconium
Authors: Henderson Elizabeth MA , Tappin David , Young David , Favretto Donata , Mactier Helen
Published: March 2023

Objective

Knowledge of alcohol consumption in pregnancy is important for early identification of children with fetal alcohol spectrum disorder. We investigated whether alcohol biomarkers fatty acid ethyl esters (FAEEs) and ethyl glucuronide (EtG) in meconium are predicted by maternal or newborn demographics and/or correlate with confidential early postnatal self-report of alcohol consumption in pregnancy.

Design

Anonymised, observational population-based study.

Setting

Inner-city maternity unit, Glasgow, UK.

Patients

Singleton mother/infant dyads delivering every fourth day.

Interventions

Mother: confidential postnatal interview. Baby: meconium sample for FAEEs and EtG.

Results

840/908 mothers consented. 370 (46.4%) reported alcohol consumption in pregnancy, generally of modest amount; for 114 (13.6%) this was after 20 weeks’ gestation. Alcohol consumption in later pregnancy was more commonly reported by older (31.3 vs 29.5 years) women of white British ethnicity (p<0.05); their babies were on average 118 g heavier (p=0.032). FAEEs were identified in all meconium samples; concentration was ≥600 ng/g in 39.6%. EtG concentration was ≥30 ng/g in 14.5%. Neither biomarker was associated with maternal age, body mass index or socioeconomic status but when EtG was ≥30 ng/g, the mother was less likely to identify as white British (71.3% vs 81.8%, p=0.028). Sensitivities of FAEEs ≥600 ng/g and EtG ≥30 ng/g were 43.1% and 11.6%, respectively for postnatal self-report of alcohol use in later pregnancy (specificities 60.6% and 84.8%).

Conclusions

FAEEs and EtG measured in meconium have low sensitivity and specificity for self-reported alcohol consumption after 20 weeks’ gestation in an unselected Scottish population.
Intraocular medulloepithelioma clinical features and management of 11 cases
Authors: Yi Xiuqian , Meng Fengxi , Bi Yingwen , He Lin , Qian Jiang , Xue Kang
Published: March 2023

Aims

To describe the clinical features, imaging characteristics, histopathology, treatment and outcomes of intraocular medulloepithelioma.

Methods

Medical records of 11 patients with clinically or histopathologically confirmed medulloepithelioma were retrieved and reviewed. Clinical features, diagnostic challenges, imaging characteristics, management, histopathology and prognosis were assessed.

Results

The median age of the patients at initial diagnosis was 4 years, with the most common manifestations being leukocoria (five eyes), loss of vision (four eyes), ocular pain (one eye) and ophthalmic screening (one eye). The clinical signs include a grey-white ciliary body lesion, cataract or lens subluxation, secondary glaucoma and evident cysts. The ultrasound biomicroscopy (UBM) imaging most commonly displays ciliary body mass with intratumoural cysts (nine eyes). Three patients underwent surgery for cataract or glaucoma while the tumours were incidentally found. Two of the three patients managed by eye preserve treatments eventually required enucleation because of local tumour recurrence or phthisis. One patient treated with intra-arterial chemotherapy and cryotherapy had successful tumour regression and globe salvage.

Conclusions

Initial misdiagnosis, delay in diagnosis and subsequent misdirected management is not uncommon in medulloepithelioma. The presence of multiple cysts in the tumour and retrolental neoplastic cyclitic membrane detected by UBM can offer certain information. Selective intra-arterial melphalan may prevent further tumour growth, but longer follow-up is necessary until treatment efficacy is fully evaluated.
FRACTAL PROPERTIES OF THE GENERALIZED MANDELBROT SET WITH COMPLEX EXPONENT
Authors: LIU SHUAI , XU XIYU , SRIVASTAVA GAUTAM , SRIVASTAVA HARI M.
Published: March 2023

Mandelbrot set, which was provided as a highlight in fractal and chaos, is studied by many researchers. With the extension of Mandelbrot set to generalized [Formula: see text] set with different kinds of exponent [Formula: see text] ([Formula: see text] set), properties are hard to understand when [Formula: see text] is a complex number. In this paper, fractal property of generalized [Formula: see text] set with complex exponent [Formula: see text] is studied. First, a relation is constructed between generalized [Formula: see text] set with complex and real exponent. Then, distribution of [Formula: see text] set on complex plane is researched. Meanwhile, symmetry of generalized [Formula: see text] set is proved. Finally, graphics, generated by escape time algorithm, are the validated results of this paper.
AN IMAGE ENCRYPTION TECHNIQUE BASED ON DISCRETE WAVELET TRANSFORM AND FRACTIONAL CHAOTIC CRYPTOVIROLOGY
Authors: ABD-ELHAFIEZ WALAA M. , ABDEL-ATY MAHMOUD , YANG XIAO-JUN , BALOBAID AWATEF
Published: March 2023

In this paper, we present a new encryption method based on discrete wavelet transform (DWT). This method provides a number of advantages as a pseudo randomness and sensitivity due to the variation of the initial values. We start by decomposing the image with spatial reconstruction by DWT, followed by preformation by fractional chaotic cryptovirology and Henon map keys for space encryption. Bearing in mind the rapid pace of change in the fields of fractional chaotic cryptovirology, our findings suggest that the proposed method is too powerful relative to the key sensitivity, histogram, entropy and correlation coefficient.
A CONTINUAL LEARNING MODEL FOR COATINGS HARDNESS PREDICTION BASED ON ARTIFICIAL NEURAL NETWORK WITH ELASTIC WEIGHT CONSOLIDATION
Authors: LEI DA , WANG QIANZHI , ZHOU FEI , KONG JIZHOU , ZHOU ZHIFENG
Published: March 2023

In order to continuously update the prediction model based on the ever-expanding data set solely, this study established a continual learning model, i.e. the elastic weight consolidation (EWC)-based artificial neural network (ANN) model to predict the hardness of Ni–Cu–CrBN coating that could be used in tribology field. The results showed that after being trained by the ever-expanding dataset, the determination coefficient [Formula: see text] of the normal ANN model on old data decreased to 0.8421 while that of the EWC-based ANN model was still 0.9836. It was indicated that the EWC-based ANN model presented good performance on both new and old data after being trained by the ever-expanding dataset solely, which saved time and was more in line with practical application.
Finite-dimensional Nichols algebras over the Suzuki algebras II: Simple Yetter–Drinfeld modules of AN2n+1μλ
Authors: Shi Yuxing
Published: March 2023

In this paper, the author gives a complete set of simple Yetter–Drinfeld modules over the Suzuki algebra [Formula: see text] and investigates the Nichols algebras over those irreducible Yetter–Drinfeld modules. The finite-dimensional Nichols algebras of diagonal type are of Cartan type [Formula: see text], [Formula: see text], [Formula: see text], Super type [Formula: see text] and the Nichols algebra [Formula: see text]. And the involved finite-dimensional Nichols algebras of non-diagonal type are [Formula: see text], [Formula: see text] and [Formula: see text]-dimensional. The left three unsolved cases are set as open problems. In particular, all finite-dimensional Nichols algebras are given for simple Yetter–Dinfeld modules over [Formula: see text].
Detecting Mental Distresses Using Social Behavior Analysis in the Context of COVID-19: A Survey
Authors: Dhelim Sahraoui , Chen Liming , Das Sajal K. , Ning Huansheng , Nugent Chris , Leavey Gerard , Pesch Dirk , Bantry-White Eleanor , Burns Devin
Published: March 2023

Online social media provides a channel for monitoring people’s social behaviors from which to infer and detect their mental distresses. During the COVID-19 pandemic, online social networks were increasingly used to express opinions, views, and moods due to the restrictions on physical activities and in-person meetings, leading to a significant amount of diverse user-generated social media content. This offers a unique opportunity to examine how COVID-19 changed global behaviors regarding its ramifications on mental well-being. In this article, we surveyed the literature on social media analysis for the detection of mental distress, with a special emphasis on the studies published since the COVID-19 outbreak. We analyze relevant research and its characteristics and propose new approaches to organizing the large amount of studies arising from this emerging research area, thus drawing new views, insights, and knowledge for interested communities. Specifically, we first classify the studies in terms of feature extraction types, language usage patterns, aesthetic preferences, and online behaviors. We then explored various methods (including machine learning and deep learning techniques) for detecting mental health problems. Building upon the in-depth review, we present our findings and discuss future research directions and niche areas in detecting mental health problems using social media data. We also elaborate on the challenges of this fast-growing research area, such as technical issues in deploying such systems at scale as well as privacy and ethical concerns.
Software Fault Tolerance in Real-Time Systems: Identifying the Future Research Questions
Authors: Reghenzani Federico , Guo Zhishan , Fornaciari William
Published: March 2023

Tolerating hardware faults in modern architectures is becoming a prominent problem due to the miniaturization of the hardware components, their increasing complexity, and the necessity to reduce costs. Software-Implemented Hardware Fault Tolerance approaches have been developed to improve system dependability regarding hardware faults without resorting to custom hardware solutions. However, these come at the expense of making the satisfaction of the timing constraints of the applications/activities harder from a scheduling standpoint. This article surveys the current state-of-the-art of fault tolerance approaches when used in the context of real-time systems, identifying the main challenges and the cross-links between these two topics. We propose a joint scheduling-failure analysis model that highlights the formal interactions among software fault tolerance mechanisms and timing properties. This model allows us to present and discuss many open research questions with the final aim to spur future research activities.
The Genesis of Uncertainty: Structural Analysis of Stochastic Chaos in Finance Markets
Authors: Musaev Alexander , Makshanov Andrey , Grigoriev Dmitry
Published: March 2023

The presented article is methodological in nature and is devoted to the analysis of observation series of financial asset quotation changes in capital markets. The most important feature of these processes is their instability, which manifests itself in high sensitivity to seemingly minor disturbing factors. This phenomenon is well-studied in the theory of nonlinear dynamical systems and is described by models of deterministic chaos. However, for the processes considered in the article, the dynamic instability of the immersion environment is exacerbated by stochastic uncertainty caused by random fluctuations in the pricing process. As a result, describing observation series of quotations of financial assets is difficult because it involves stochastic chaos. This article analyzes and classifies chaotic series of observations to help model and forecast related processes.
Effect of Posttreatment on the Catalytic Performances of Fe-N-C for Oxygen Reduction Reactions
Authors: Kim Dong-gun , Jang Injoon , Sohn Yeonsun , Joo Eunhye , Jung Chanil , Kim Nam Dong , Jung Jae Young , Paidi Vinod K. , Lee Kug-Seung , Kim Pil , Yoo Sung Jong
Published: March 2023

Herein, we report the significance of posttreatment in the design of high-performance Fe-N-C-type catalysts for oxygen reduction reaction (ORR). Enhancing the catalytic performance of Fe-N-C requires a postprocess for removing the aggregated iron species formed during high-temperature pyrolysis since they have a negative effect on ORR. We were able to obtain a catalyst precursor for the Fe-N-C reaction via pyrolysis with iron-adsorbed 1,8-diaminonaphthalene (FeDN), which was then treated with a concentrated HCl solution for the removal of the aggregated iron species produced. The HCl-treated FeDN was subsequently annealed at various temperatures to investigate the effect of the annealing process on the physical properties and ORR performance. The annealing temperature was a critical factor affecting the residual contents of impurities, as well as the active component and the electronic state of nitrogen. We also examined the influence of different types of acid (HCl, H2SO4, and HNO3) on the catalytic performance. The type of acid used for removing aggregated iron species had an impact on both the Fe contents and the relative nitrogen species content. Among the catalysts tested, the catalyst prepared by annealing the HCl-treated FeDN at 700°C had the best ORR performance. Although its initial ORR performance in acidic conditions was lower than that of a commercial Pt/C, it was more durable. In alkaline conditions, it delivered a comparable initial ORR performance to Pt/C and also exhibited higher durability.
Supplementary Figure 1 from Blockade of B7-H1 and PD-1 by Monoclonal Antibodies Potentiates Cancer Therapeutic Immunity
Authors: Hirano Fumiya , Kaneko Katsumi , Tamura Hideto , Dong Haidong , Wang Shengdian , Ichikawa Masao , Rietz Cecilia , Flies Dallas B. , Lau Julie S. , Zhu Gefeng , Tamada Koji , Chen Lieping
Published: March 2023

Supplementary Figure 1 from Blockade of B7-H1 and PD-1 by Monoclonal Antibodies Potentiates Cancer Therapeutic Immunity
Supplementary Figures 1-4, with Legends from Homeobox Msx1 Interacts with p53 Tumor Suppressor and Inhibits Tumor Growth by Inducing Apoptosis
Authors: Park Kyoungsook , Kim Kwangbae , Rho Seung Bae , Choi Kyusam , Kim Dojin , Oh Sun-Hee , Park Jinhee , Lee Seung-Hoon , Lee Je-Ho
Published: March 2023

Supplementary Figures 1-4, with Legends from Homeobox Msx1 Interacts with p53 Tumor Suppressor and Inhibits Tumor Growth by Inducing Apoptosis
Supplementary Material from PIK3CA Mutations Correlate with Hormone Receptors, Node Metastasis, and ERBB2, and Are Mutually Exclusive with PTEN Loss in Human Breast Carcinoma
Authors: Saal Lao H. , Holm Karolina , Maurer Matthew , Memeo Lorenzo , Su Tao , Wang Xiaomei , Yu Jennifer S. , Malmström Per-Olof , Mansukhani Mahesh , Enoksson Jens , Hibshoosh Hanina , Borg Åke , Parsons Ramon
Published: March 2023

Supplementary Material from PIK3CA Mutations Correlate with Hormone Receptors, Node Metastasis, and ERBB2, and Are Mutually Exclusive with PTEN Loss in Human Breast Carcinoma
Table S5 from Candidate Genes in Breast Cancer Revealed by Microarray-Based Comparative Genomic Hybridization of Archived Tissue
Authors: Nessling Michelle , Richter Karsten , Schwaenen Carsten , Roerig Peter , Wrobel Gunnar , Wessendorf Swen , Fritz Björn , Bentz Martin , Sinn Hans-Peter , Radlwimmer Bernhard , Lichter Peter
Published: March 2023

Chromosomal localization, name, and ID for each DNA test sequence (BAC and PAC clones) immobilized on the microarray of use
Supplementary Figure 1 from ΔNp63α Up-Regulates the Hsp70 Gene in Human Cancer
Authors: Wu Guojun , Osada Motonobu , Guo Zhongmin , Fomenkov Alexey , Begum Shahnaz , Zhao Ming , Upadhyay Sunil , Xing Mingzhao , Wu Feng , Moon Chulso , Westra William H. , Koch Wayne M. , Mantovani Roberto , Califano Joseph A. , Ratovitski Edward , Sidransky David , Trink Barry
Published: March 2023

Supplementary Figure 1 from ΔNp63α Up-Regulates the Hsp70 Gene in Human Cancer
Supplementary Table from Glycolytic Enzymes Can Modulate Cellular Life Span
Authors: Kondoh Hiroshi , Lleonart Matilde E. , Gil Jesus , Wang Jing , Degan Paolo , Peters Gordon , Martinez Dolores , Carnero Amancio , Beach David
Published: March 2023

Supplementary Table from Glycolytic Enzymes Can Modulate Cellular Life Span
Supplementary Data from Wavelet Transformations of Tumor Expression Profiles Reveals a Pervasive Genome-Wide Imprinting of Aneuploidy on the Cancer Transcriptome
Authors: Aggarwal Amit , Leong Siew Hong , Lee Cheryl , Kon Oi Lian , Tan Patrick
Published: March 2023

2 Tables, 2 Figures, 3 Technical Notes
Supplementary Figure from Mutations in Apc and p53 Synergize to Promote Mammary Neoplasia
Authors: Méniel Valérie , Hay Trevor , Douglas-Jones Anthony , Sansom Owen J. , Clarke Alan R.
Published: March 2023

Supplementary Figure from Mutations in Apc and p53 Synergize to Promote Mammary Neoplasia
Table S2 from Expression Analysis of Juvenile Pilocytic Astrocytomas by Oligonucleotide Microarray Reveals Two Potential Subgroups
Authors: Wong Kwong-Kwok , Chang Yi-Mieng , Tsang Yvonne T.M. , Perlaky Laszlo , Su Jack , Adesina Adekunle , Armstrong Dawna L. , Bhattacharjee Meenakshi , Dauser Robert , Blaney Susan M. , Chintagumpala Murali , Lau Ching C.
Published: March 2023

Genes differentiate two groups of JPA Hanash data
Supplementary Data from AMPK Phosphorylates ZDHHC13 to Increase MC1R Activity and Suppress Melanomagenesis
Authors: Sun Yu , Li Xin , Yin Chengqian , Zhang Judy , Liang Ershang , Wu Xianfang , Ni Ying , Arbesman Joshua , Goding Colin R. , Chen Shuyang
Published: March 2023

Figure S1-S5
Supplemental Methods from A Systematic Review and Multilevel Regression Analysis Reveals the Comorbidity Prevalence in Cancer
Authors: Vrinzen Cilla E.J. , Delfgou Linn , Stadhouders Niek , Hermens Rosella P.M.G. , Merkx Matthias A.W. , Bloemendal Haiko J. , Jeurissen Patrick P.T.
Published: March 2023

Search strings for the literature search and the quality assesment tools
Supplementary Table S4 from CD73-Dependent Adenosine Signaling through Adora2b Drives Immunosuppression in Ductal Pancreatic Cancer
Authors: Faraoni Erika Y. , Singh Kanchan , Chandra Vidhi , Le Roux Olivereen , Dai Yulin , Sahin Ismet , O'Brien Baylee J. , Strickland Lincoln N. , Li Le , Vucic Emily , Warner Amanda N. , Pruski Melissa , Clark Trent , Van Buren George , Thosani Nirav C. , Bynon John S. , Wray Curtis J. , Bar-Sagi Dafna , Poulsen Kyle L. , Vornik Lana A. , Savage Michelle I. , Sei Shizuko , Mohammed Altaf , Zhao Zhongming , Brown Powel H. , Mills Tingting , Eltzschig Holger K. , McAllister Florencia , Bailey-Lundberg Jennifer M.
Published: March 2023

Table S4
Supplementary Table S3 from CD73-Dependent Adenosine Signaling through Adora2b Drives Immunosuppression in Ductal Pancreatic Cancer
Authors: Faraoni Erika Y. , Singh Kanchan , Chandra Vidhi , Le Roux Olivereen , Dai Yulin , Sahin Ismet , O'Brien Baylee J. , Strickland Lincoln N. , Li Le , Vucic Emily , Warner Amanda N. , Pruski Melissa , Clark Trent , Van Buren George , Thosani Nirav C. , Bynon John S. , Wray Curtis J. , Bar-Sagi Dafna , Poulsen Kyle L. , Vornik Lana A. , Savage Michelle I. , Sei Shizuko , Mohammed Altaf , Zhao Zhongming , Brown Powel H. , Mills Tingting , Eltzschig Holger K. , McAllister Florencia , Bailey-Lundberg Jennifer M.
Published: March 2023

Table S3
Supplementary Figures from CD73-Dependent Adenosine Signaling through Adora2b Drives Immunosuppression in Ductal Pancreatic Cancer
Authors: Faraoni Erika Y. , Singh Kanchan , Chandra Vidhi , Le Roux Olivereen , Dai Yulin , Sahin Ismet , O'Brien Baylee J. , Strickland Lincoln N. , Li Le , Vucic Emily , Warner Amanda N. , Pruski Melissa , Clark Trent , Van Buren George , Thosani Nirav C. , Bynon John S. , Wray Curtis J. , Bar-Sagi Dafna , Poulsen Kyle L. , Vornik Lana A. , Savage Michelle I. , Sei Shizuko , Mohammed Altaf , Zhao Zhongming , Brown Powel H. , Mills Tingting , Eltzschig Holger K. , McAllister Florencia , Bailey-Lundberg Jennifer M.
Published: March 2023

Supplementary Figures S1-9
REAGENT or RESOURCE from USP48 Stabilizes Gasdermin E to Promote Pyroptosis in Cancer
Authors: Ren Yidan , Feng Maoxiao , Hao Xiaodong , Liu Xiaoyan , Li Juan , Li Peilong , Gao Jie , Qi Qiuchen , Du Lutao , Wang Chuanxin , Wang Qin , Wang Yunshan
Published: March 2023

Reagent or Resource
Original Image of western blot from USP48 Stabilizes Gasdermin E to Promote Pyroptosis in Cancer
Authors: Ren Yidan , Feng Maoxiao , Hao Xiaodong , Liu Xiaoyan , Li Juan , Li Peilong , Gao Jie , Qi Qiuchen , Du Lutao , Wang Chuanxin , Wang Qin , Wang Yunshan
Published: March 2023

Original Image of western blot
Table S1 from TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis
Authors: Anstine Lindsey J. , Majmudar Parth R. , Aponte Amy , Singh Salendra , Zhao Ran , Weber-Bonk Kristen L. , Abdul-Karim Fadi W. , Valentine Mitchell , Seachrist Darcie D. , Grennel-Nickelson Katelyn E. , Cuellar-Vite Leslie , Sizemore Gina M. , Sizemore Steven T. , Webb Bryan M. , Thompson Cheryl L. , Keri Ruth A.
Published: March 2023

Table S1
Supplementary Data from SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
Authors: Chambers Courtney , Cermakova Katerina , Chan Yuen San , Kurtz Kristen , Wohlan Katharina , Lewis Andrew Henry , Wang Christiana , Pham Anh , Dejmek Milan , Sala Michal , Loeza Cabrera Mario , Aguilar Rogelio , Nencka Radim , Lacorazza H. Daniel , Rau Rachel E. , Hodges H. Courtney
Published: March 2023

Supplementary Materials
S4 from TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis
Authors: Anstine Lindsey J. , Majmudar Parth R. , Aponte Amy , Singh Salendra , Zhao Ran , Weber-Bonk Kristen L. , Abdul-Karim Fadi W. , Valentine Mitchell , Seachrist Darcie D. , Grennel-Nickelson Katelyn E. , Cuellar-Vite Leslie , Sizemore Gina M. , Sizemore Steven T. , Webb Bryan M. , Thompson Cheryl L. , Keri Ruth A.
Published: March 2023

Supplemental Figure 4
Supplementary Table S1 from PGC1α Degradation Suppresses Mitochondrial Biogenesis to Confer Radiation Resistance in Glioma
Authors: Zhao Mengjie , Li Yanhui , Lu Chenfei , Ding Fangshu , Xu Miao , Ge Xin , Li Mengdie , Wang Zhen , Yin Jianxing , Zhang Junxia , Wang Xiefeng , Ge Zehe , Xiao Hong , Xiao Yong , Liu Hongyi , Liu Wentao , Cao Yuandong , Wang Qianghu , You Yongping , Wang Xiuxing , Yang Kun , Shi Zhumei , Qian Xu
Published: March 2023

Table S1. Oligos used in this study
Supplementary Figures from PGC1α Degradation Suppresses Mitochondrial Biogenesis to Confer Radiation Resistance in Glioma
Authors: Zhao Mengjie , Li Yanhui , Lu Chenfei , Ding Fangshu , Xu Miao , Ge Xin , Li Mengdie , Wang Zhen , Yin Jianxing , Zhang Junxia , Wang Xiefeng , Ge Zehe , Xiao Hong , Xiao Yong , Liu Hongyi , Liu Wentao , Cao Yuandong , Wang Qianghu , You Yongping , Wang Xiuxing , Yang Kun , Shi Zhumei , Qian Xu
Published: March 2023

Supplementary Figures and Figure legends
S2 Legend from TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis
Authors: Anstine Lindsey J. , Majmudar Parth R. , Aponte Amy , Singh Salendra , Zhao Ran , Weber-Bonk Kristen L. , Abdul-Karim Fadi W. , Valentine Mitchell , Seachrist Darcie D. , Grennel-Nickelson Katelyn E. , Cuellar-Vite Leslie , Sizemore Gina M. , Sizemore Steven T. , Webb Bryan M. , Thompson Cheryl L. , Keri Ruth A.
Published: March 2023

Supplemental Figure 2 Legend
S1 from TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis
Authors: Anstine Lindsey J. , Majmudar Parth R. , Aponte Amy , Singh Salendra , Zhao Ran , Weber-Bonk Kristen L. , Abdul-Karim Fadi W. , Valentine Mitchell , Seachrist Darcie D. , Grennel-Nickelson Katelyn E. , Cuellar-Vite Leslie , Sizemore Gina M. , Sizemore Steven T. , Webb Bryan M. , Thompson Cheryl L. , Keri Ruth A.
Published: March 2023

Supplemental Figure 1
S1 Legend from TLE3 Sustains Luminal Breast Cancer Lineage Fidelity to Suppress Metastasis
Authors: Anstine Lindsey J. , Majmudar Parth R. , Aponte Amy , Singh Salendra , Zhao Ran , Weber-Bonk Kristen L. , Abdul-Karim Fadi W. , Valentine Mitchell , Seachrist Darcie D. , Grennel-Nickelson Katelyn E. , Cuellar-Vite Leslie , Sizemore Gina M. , Sizemore Steven T. , Webb Bryan M. , Thompson Cheryl L. , Keri Ruth A.
Published: March 2023

Supplemental Figure 1 Legend
Table S5 from The Ratio of Toxic-to-Nontoxic miRNAs Predicts Platinum Sensitivity in Ovarian Cancer
Authors: Patel Monal , Wang Yinu , Bartom Elizabeth T. , Dhir Rohin , Nephew Kenneth P. , Matei Daniela , Murmann Andrea E. , Lengyel Ernst , Peter Marcus E.
Published: March 2023

Summary of the miRNAs most relevant to the Pt-R OC cells and patients identified in this study.