bluuebunny/crossref_metadata_2025 huggingface dataset:
Iglesia católica, una estructura institucional compleja
Authors: Morad Guadalupe
Published: February 2025

La obra La Verdad los hará libres publicada en el 2023, recorre las acciones, expresiones y omisiones de los distintos miembros de la Iglesia católica en uno de los periodos más trágicos de la historia argentina, 1966-1983, en que la institución eclesiástica atravesó la gran renovación operada por el Concilio Vaticano II. Sus autores, además de considerar las numerosas investigaciones previas realizadas sobre la época, aportan el resultado del acceso a distintos archivos eclesiásticos disponibles a la consulta. A partir de lo compartido sobre la obra mencionada, en el conversatorio del 18 de octubre del 2023 en el Instituto de Estudios Histórico-Sociales (IHES) de Tandil (Buenos Aires, Argentina), este escrito se focalizará en la complejidad propia de la Iglesia católica, institución organizada en jurisdicciones o diócesis presentes en distintos estados nacionales, cuyos miembros – laicas y laicos, consagradas y consagrados, sacerdotes, congregaciones de religiosas y religiosos, y obispos –, son protagonistas en espacios eclesiales dinámicos y con niveles de responsabilidad diferentes.
Despotismos y libertades en el Pacífico norte. Contribución a una genealogía del liberalismo autoritario entre China, Estados Unidos y México, 1895-1911
Authors: Blitstein Pablo A.
Published: February 2025

A fines del siglo XIX y principios del XX, entre Asia y América, muchos defensores entusiastas de una “libertad” inspirada del liberalismo político y económico reclamaban paradójicamente un poder fuerte, incluso “despótico”, capaz de encarnar sus ideales en leyes e instituciones. ¿Qué argumentos utilizaban para combinar “libertad” con “despotismo”? Y sobre la base de este objetivo común, ¿qué vínculos o modos de colaboración transcontinental estos grupos pudieron establecer entre ellos? A partir del análisis de un proyecto migratorio, el establecimiento de una Nueva China en el México de Porfirio Díaz, intentaremos entender cómo letrados chinos, notables de la diáspora, empresarios estadounidenses y positivistas mexicanos convergían en representaciones similares del orden político y social. En esta microhistoria transcontinental del discurso político, exploraremos los modos de complementariedad entre proyectos divergentes, y contribuiremos de este modo a una genealogía global de lo que más tarde se conocería como “liberalismo autoritario”.
Los guerrilleros de Dios: “¿Cómo ser cristianos y cubanos a la vez?”. Etnografía del pentecostalismo en La Habana postsoviética (2017-2019)
Authors: Pavy Flore
Published: February 2025

El objetivo de este artículo es dar una nueva mirada a los cambios sociales, económicos, políticos e ideológicos ocurridos en Cuba tras el colapso del bloque soviético, a través del prisma aún poco explorado del acelerado desarrollo de las iglesias pentecostales en La Habana. A partir de un análisis de los espacios de culto protestantes posrevolucionarios que florecen en el occidente del país y particularmente en su capital, se pretende describir las formas locales de liturgia marcadas por un súbito y masivo giro carismático. Estas liturgias se inspiran en gran medida en los ritos evangélicos norteamericanos importados por pastores extranjeros a través de redes internacionales de formación, pero también incorporan diversos elementos autóctonos tomados en particular de los códigos rituales de los cultos de posesión, así como ciertos motivos específicos de la retórica revolucionaria. Particularmente activas y dinámicas -"en guerra"-, estas iglesias llevan a cabo vastas campañas de evangelización en los barrios pobres de La Habana y en las provincias marginales del país.
Équipes éditoriales et enjeux ecclésiologiques
Authors: Sère Bénédicte
Published: February 2025

Ce passage traite de la frontière entre les controverses ecclésiologiques à la fin du Moyen Âge et les politiques éditoriales au tournant des XVe et XVIe siècles. De nombreux traités polémiques et débats textuels se trouvent dans les manuscrits médiévaux, qui sont passés à l’ère moderne par le biais d’incunables et d’éditions imprimées ultérieures. L’agencement des textes compilés dans les éditions imprimées, depuis les incunables jusqu’au XXe siècle, a nécessité un travail sophistiqué de la part des équipes et des éditeurs. Après analyse, le travail en soi des compilateurs peut être considéré comme une contribution aux controverses elles-mêmes. L’accent est ici mis sur l’œuvre du grand théologien du XVe siècle Jean Gerson (1363-1429), chancelier de l’université de Paris, père et prédicateur au concile de Constance, théoricien de l’Église, de la mystique, de la théologie morale et de la pensée politique et ecclésiologique. Il s’agit de comprendre comment ses textes, à l’origine épars – sermons, colloques, notes de cours, lettres – ont été agencés pour former progressivement un corpus canonique : les Œuvres complètes de Jean Gerson. En compilant et en codifiant ses textes, Gerson est passé du statut d’autorité médiévale à celui d’auteur. Son œuvre a alimenté les débats et les controverses sur l’Église et sa gouvernance jusqu’à aujourd’hui.
Quand les femmes sont faites théologiennes : Les Dames illustres (1665) de Jacquette Guillaume
Authors: Mueggler Nina
Published: February 2025

Dans Les Dames illustres (1665), Jacquette Guillaume œuvre en faveur du savoir féminin, qu’elle met en scène grâce à une ample galerie de femmes choisies tant pour leur vertu que pour leur érudition. Mais surtout, elle révolutionne la traditionnelle Querelle des femmes en la doublant d’une querelle proprement religieuse, dans laquelle elle attaque, grâce à une véritable brigade de théologiennes, simultanément plusieurs « hérésiarques ». L’enquête menée sur ce riche recueil permet de mieux saisir les multiples stratégies de subversion déployées par une autrice qui se fait aussi compilatrice que mystificatrice.
Entre conservation, survie et sécurisation : Quel(s) modèle(s) de gouvernance dans le parc du W-Bénin ?
Authors: Gnanguênon Amandine , Mossi Abdel-Aziz
Published: February 2025

Ce papier examine l’évolution des agendas, des intérêts et des enjeux à différentes échelles (locale, nationale, régionale et internationale) autour du parc du W-Bénin. Il analyse comment la gouvernance de la zone est façonnée par la conservation des aires protégées (pour des raisons politiques, économiques ou idéologiques), la prise en compte des besoins fondamentaux des communautés, l’opportunisme des groupes armés et les efforts de sécurisation face aux attaques récurrentes contre l’État et les populations. Cet article est issu d’une recherche documentaire à partir de publications académiques et de rapport institutionnels ainsi que d’une vingtaine d’entretiens qualitatifs conduits à Cotonou et par téléphone en mars 2022 avec des acteurs clés impliqués dans la gestion du Parc et avec les communautés riveraines du Parc du W dans les communes de Karimama, Malanville et Banikoara en août 2022. Il révèle que, depuis son classement au Patrimoine mondial de l’humanité de l’UNESCO, la gestion du parc du W-Bénin concentre de nombreuses formes de gouvernance locales, nationales ou régionales. Cette gouvernance tantôt exclusivement étatique, tantôt participative, tantôt privatisée recèle des enjeux de pouvoir qui dépassent la simple question écologique. Autrefois placée au centre des préoccupations de conservation et de survie, la gestion du parc du W doit désormais prendre en compte les défis sécuritaires que fait peser sur elle la menace des groupes armés qui prolifèrent dans la région et dont la présence compromet les ambitions de gouvernance de cette aire protégée.
Artificial Intelligence as a Sustainable Tool for Optimizing the Wastewater Treatment Plant
Authors: Arya Adarsh Kumar , Shreya
Published: February 2025

The field of artificial intelligence (AI) is advancing at a rapid pace. The evolving technology can replicate practical scenarios in different industries, such as water purification and wastewater treatment. It has demonstrated its value in agriculture, the automotive industry, banking, finance, space exploration, and creative technology. Wastewater treatment has seen significant improvements with the integration of artificial intelligence, which enhances efficiency, speed, and autonomy. Nevertheless, there are notable obstacles and limitations to address, such as data management challenges, interpretability concerns, model replicability and consistency issues, and the need for scholarly transparency. Improving model causality, clarity, data management, and repeatability are proposed solutions. The chapter introduced some of the recent artificial intelligence based optimization methodologies to optimize waste water treatment plants.
Enhancing Wastewater Stabilization Ponds for Treating Domestic Wastewater Using Machine Learning
Authors: Venkat Narayana Rao T. , Yellavajhala Shiva Kashyap , Harshith Muddasani , Gowda K. Siva Kumar
Published: February 2025

In the realm of wastewater treatment, Wastewater Stabilization Ponds (WSPs) are highly regarded for their efficiency, particularly when incorporating baffle walls (BWs) into their design. These BWs play a crucial role in minimizing space requirements and improving contaminant removal, albeit at the expense of increased construction material usage. To find the best configuration, a thorough analysis was first carried out utilizing typical methodology (TM) design worksheets for WSPs. This phase validated the effectiveness of BWs by showing a considerable reduction in both WSPs area and hydraulic retention time (RT). Within the MM framework, additional reductions in WSPs area and RT were attained, coupled with a 5% drop in necessary concrete volume compared to TM, by employing the interior-point approach in MATLAB and the generalized reduced gradient (GRG) algorithm in MS Excel Solver. While these findings highlight the effectiveness of MM in optimizing WSPs, there is potential for exploring alternative algorithms to achieve more favorable results.
Enhanced Autonomous Driving
Authors: Waga Abderrahim , Benhlima Said , Bekri Ali
Published: February 2025

The process of repairing potholes entails significant financial and temporal resources. This article presents cutting-edge approaches to pothole detection employing convolutional neural network techniques, focusing exclusively on RGB input images. The primary objective of this research is to assess the performance of three iterations of the You Only Look Once model, namely, YOLOv8 Nano, Small, and Medium, for pothole detection. Additionally, the proposal suggests a system to alert drivers about identified potholes and recommend alternative routes. The design of the solution enables it to function effectively in real-time in various lighting conditions, including low-light scenarios. Evaluation metrics include inference speed and detection accuracy. We merged diverse datasets from multiple sources to facilitate model training and accelerate convergence. The mean average precision at IoU threshold 0.5 (mAP@0.5) for YOLOv8 n, s, and m models is reported as 66%, 71%, and 51%, respectively.
Addressing Work Place Bullying in Digital Age
Authors: Wilson Shanika Lavi , Wilson Kevin M.
Published: February 2025

As technology advances, workplace bullying continues to be a pervasive issue that impacts individuals, organizations, and society as a whole. This paper comprehensively analyzes workplace bullying through micro, mezzo, and macro perspectives. The micro level focuses on individual interventions, exploring how employees—victims and perpetrators—can be supported through counseling, emotional intelligence training, and resilience-building efforts. The mezzo level investigates organizational policies, leadership roles, and workplace culture, emphasizing the importance of strong anti-bullying policies, inclusive practices, and effective conflict resolution mechanisms. At the macro level, the paper examines the role of legal frameworks, cultural norms, and global standards in shaping workplace practices, focusing on public health implications and international collaboration. By integrating these perspectives, the paper highlights how workplace bullying is not just an individual or organizational issue but a systemic problem requiring coordinated efforts at all levels.
Conceptual Study on Impact of Human Resource Practices on Organizational Performance in State Universities in Sri Lanka: The Mediating Role of Employee Attitude
Authors: Azhar M. T. Ahamed , Ismail M. B. M.
Published: February 2025

The impact of Human Resource (HR) practices on the performance of state universities in Sri Lanka is analyzed in the context of mediating employee attitudes encompassing customer orientation, resource management, internal business processes, and learning and growth. The objectives of this research are to identify the determine factors influencing HR practices, organizational performance, and employee attitudes in Sri Lankan state universities. It also aims to establish the link between HR practices and organizational performance in these institutions while exploring the mediating role of employee attitude between HR Practices and organizational performance in State Universities in Sri Lanka. Ultimately, the research seeks to construct a conceptual model that delineates the conceptual relationships between HR practices and organizational performance factors within Sri Lankan state universities. This research is structured in two stages: the first phase is classified as exploratory research, during which a conceptual model is developed based on identified factors. The subsequent stage is a conclusive research design, combining descriptive and causal research methods. The researcher has collected a total of 184 articles as sample data pertaining to HR practices, organizational performance, and employee attitudes. Secondary sources were also consulted for data collection. Qualitative analysis has revealed that the factors influencing HR practices in Sri Lankan state universities encompass Recruitment and Selection (RS), Training and Development (TD), Performance Appraisal (PA), Reward Management and Compensation (RMC), Working Environment (WE), and Organizational Culture (OC). Factors influencing Organizational Performance (OP) are associated with Customers (Students), Resources (Academic and Administrative staff), Internal Business Processes (Degree programmes, etc.), Innovation, Learning, and Growth (ILG). Employee attitude factors include Job Satisfaction (JS), Employee Engagement (EE), Employee Commitment (EC), Employee Involvement (EI), as well as affective, behavioral, and cognitive components of attitude. Utilizing these identified factors, a conceptual model has been devised to elucidate the conceptual relationships between HR practices and organizational performance factors, taking into account the mediating influence of employee attitude factors.
Unveiling the “common soil” of cardiovascular disease and cancer
Authors: Iacoviello Licia , Donati Maria Benedetta
Published: February 2025

The complex relationship between cardiovascular disease (CVD) and cancer has raised significant research interest, supported by growing evidence that these leading causes of morbidity and mortality share several pathogenetic aspects. The “common soil“ hypothesis postulates that CVD and cancer emerge from the same piece of earth as distinct trees, but with intermingled roots, represented by modifiable risk factors and underlying molecular mechanisms. The integration of cardiovascular and cancer prevention through lifestyle and metabolic health improvements represents a necessity, for modern public health. This dual-benefit approach has the potential to reshape how we understand, approach, and ultimately reduce the burden of two of the world's most impactful group of diseases.
Prospective assessment of venous thromboembolism in lung cancer patients using a standardized screening protocol
Authors: Magalhães Ferreira Pedro , Ferreira Joana , Freitas Cláudia , Sousa Catarina , Araújo David , Novais Bastos Hélder , Magalhães Adriana , Fernandes Maria Gabriela
Published: February 2025

Venous thromboembolism (VTE) is highly prevalent in cancer patients. While its actual incidence remains disparate among studies, specific subpopulations, such as lung cancer patients, might be at an increased risk. We aimed to assess the impact of a screening protocol in determining both the incidence and risk factors for VTE and evaluate the usefulness of predictive biomarkers and risk stratification tools in lung cancer patients. For this purpose, we designed a prospective cohort study including all consecutive, newly diagnosed lung cancer patients between October 2023 and April 2024 in a tertiary center and assessed each patient using a standardized screening protocol. VTE screening included baseline and 3-month reassessment of coagulation tests, D-dimer levels, and imaging (duplex ultrasound of the lower limbs for deep vein thrombosis screening and contrast-enhanced thoracic computed tomography for pulmonary embolism screening). A total of 102 patients were included, of which 16 (15.7%) were diagnosed with VTE. VTE was more frequent in males (p=0.031), patients with COPD (p=0.004), and patients with metastatic disease (p=0.038), particularly those under immunotherapy (p=0.026). Patients with VTE presented a D-dimer concentration more than three times higher at baseline and fivefold the levels observed in non-VTE patients at 3 months (p=0.002). Paired with Khorana scores, D-dimer concentration 4.5 mg/L at 3 months improved the predictive capacity of this VTE risk assessment tool in patients under active treatment. Active VTE screening yielded a significant increase in diagnosis, suggesting the incidence of this complication in newly diagnosed lung cancer patients is underestimated. Risk assessment tools can be enhanced by the addition of D-dimer-based parameters.
Earned Print and Digital Media in Advancing Hypertension Management Services in Punjab, India: A Descriptive Study
Authors: Upadhyay Kritika , Goel Sonu , Jaswal Nidhi , Pratap Mahendra , Ghosh Lopa
Published: February 2025

Background:

Most often, the role of media in the wider dissemination of information about health and diseases is underscored. The present study aims to systematically analyze and describe the outreach of print and online-earned media generated during a “hypertension control project” undertaken in a state of North India.

Methods:

A descriptive cross-sectional analysis was conducted. All earned news stories published in print and online as part of the hypertension control project from January to November 2021 were included in the study. An integrated model of media communication was employed as an intervention method, which was created through a comprehensive literature study and Delphi methodology. Following a quantitative content analysis of earned media, a hypothetical value (in Indian Rupee) for print and online media was calculated.

Results:

Two hundred and eighty-five news items (154 print and 131 online) in total were published over an 11-month period, primarily (n = 153, 53.6%) in newspapers with over 70,000 readership. The earned media steadily increased over time, peaking in June and July. Most news items were feature articles (62.5%) followed by case stories (37.5%), with a prime focus on awareness generation (41.4%) among the public and increasing the capacity of stakeholders (35.1%). Press releases were highest at 53%, followed by press conferences (33.7%) and one-to-one interaction (13.3%). Most articles were focused on core hypertension (55%) and transfats (40.7%). The print and online news had a hypothetical cost of 152,970 US$ and 7,280 US$, respectively, which surpassed the resources spent on all project events.

Conclusions:

In the absence of financial support for paid media, earned media was strategically used to promote awareness about hypertension control.
Human Brucellosis Presenting with Rheumatic Manifestations: An Underdiagnosed Condition in Eastern India
Authors: Pandey Saurabh , Gupta Manoj Kumar , Rai Priyanka , Patra Arnab , Begum Nazneen Nahar , Halder Prantiki , Guha Subhashsish Kamal
Published: February 2025

Human brucellosis is a chronic systemic infection mostly presenting as afebrile illness with musculoskeletal complaints with organomegaly and diagnosis is based on serology. The diagnostic tests are sparsely available in India and even less prescribed. We report six cases of human of brucellosis presenting as fever with rheumatic manifestation along with their outcome.
How Can We Increase the Clinical Benefits of Vitamin D Supplementation in Adult People with Multiple Sclerosis?
Authors: Bugnicourt Jean-Marc
Published: February 2025

Vitamin D (VD) supplementation in adult people with multiple sclerosis (MS) remains most of the time suboptimal, linked to outdated prescription rules mainly based on good bone health. In MS, the physician should ensure that people have a normal serum 25-hydroxyvitamin D level for the maintenance of an effective immune system. Here, we highlight the pitfalls classically encountered in the prescription of Vitamin D in this population and propose a simple algorithm for optimal supplementation.
The Impact of Environmental Support on Health for Children with Hearing Impairment in Taiwan
Authors: Lin Chung-Ying , Fung Xavier C. C.
Published: February 2025

Introduction:

Children with hearing impairment (HI) often encounter difficulties in learning due to their language problems caused by HI. Therefore, children with HI also suffer from health problems, including psychological health, social relationship, and school performance. Given that the International Classification of Function, Disability, and Health proposed environment as a key element in promoting health. This study proposed to investigate the impacts of environmental support on health and learning abilities among a nationally representative sample with HI.

Methods:

A total of 163 children (94 boys; 88 first graders and 75 third graders) retrieved from the Special Needs Education Longitudinal Study were used for analysis. Questionnaire items on environmental support (3 items), impairment (1 item), learning ability (4 items), and health (4 items) were constructed in a structural equation model. Specifically, environmental support was linked to impairment, learning ability, and health; impairment was linked to learning ability and health.

Results:

Our results indicated that environmental support had positive effects on three dimensions of health (social relationship, β = 0.38; emotional functioning, β = 0.27; and school performance, β = 0.59) and learning ability (β = 0.26); negative effects on impairment (β = −0.62). Impairment had negative impacts on two dimensions of health (physical fitness and school performance, β = −0.18 and −0.22, respectively) and learning ability (β = −0.29).

Conclusions:

According to our findings, health-care professionals and school teachers may consider establishing good environmental support for children with HI. Thus, children with HI may have improved health and learning abilities.
Job Stress, Sexual Harassment, Self-Harm Behavior, and Suicidal Ideation Among Military Personnel in Taiwan
Authors: Jin Huei-Ting , Lin Yi-Ching , Strong Carol
Published: February 2025

Introduction:

The aim of this study was first to estimate the prevalence of having self-harm behavior and suicidal ideation in a sample of military personnel. Second, we examined whether work stress, sexual harassment experiences, and depression were associated with suicidal ideation and self-harm behavior.

Methods:

A cross-sectional survey was conducted in Taiwan between January and April 2016. Sample was recruited from large military bases in Taiwan, including army, navy, and air force using convenience sampling. Self-reported data on job stress, sexual harassment experiences, self-harm behavior, and suicidal ideation were collected. Multiple logistic regression was used to determine the risk factors associated with having had self-harm behavior or suicidal ideation.

Results:

Of 513 individuals surveyed, 4.5% had self-harm behavior in the past 12 months and 9% had considered suicide. The majority of the sample were male (81.9%), between 20 and 29 years old (87.7%), voluntary military service (79.7%), and single or not married (90.8%). A higher level of sexual harassment experiences, higher level of perceived work stress, interpersonal relationship, and a lower level of job satisfaction were associated with self-harm behaviors. In multivariate analysis, gender, education, perceived work stress, sexual harassment, and depression were significantly associated with having had considered suicide in the past 12 months.

Discussion:

Our study highlighted the importance of acknowledging the vulnerability of the military work environment, including self-harming tendencies and sexual harassment. Education and training to ensure gender equality should be provided through appropriate channels.
Effect of forearm and posterior wall anastomosis on gastroesophageal reflux in proximal gastrectomy patients
Authors: Yang Jia-Le , Yang Yi-Jie , Xu Lu
Published: February 2025

BACKGROUND

Proximal gastrectomy for gastric cancer often leads to postoperative gastroesophageal reflux (GER). This study compares the impact of forearm anastomosis and posterior wall anastomosis techniques on GER in patients undergoing this procedure.

AIM

To identify the most effective method for reducing reflux symptoms while preserving gastrointestinal integrity and nutritional status.

METHODS

A retrospective evaluation was conducted on 60 patients who underwent proximal gastrectomy between December 2020 and December 2023, divided equally into two groups based on the anastomosis technique used (forearm or posterior wall). GER symptoms were assessed using the GER disease questionnaire (GerdQ) preoperatively and on the first postoperative day. Biochemical markers [diamine oxidase (DAO), D-lactic acid, and endotoxin (ETX)] and nutritional indicators [serum ferritin (SF), prealbumin (PA), and albumin (ALB)] were measured to evaluate gastrointestinal barrier function and nutritional status.

RESULTS

Both groups showed significant improvements in GerdQ scores and reflux symptom scores post-treatment, with the observation group exhibiting greater reductions. Biochemical markers indicated enhanced gastrointestinal barrier function post-treatment in both groups, with notable increases in DAO, D-lactic, and ETX levels. Nutritional status indicators also demonstrated significant changes, with reductions in SF, PA, and ALB levels, suggesting an impact of treatment on inflammatory and nutritional status.

CONCLUSION

The forearm anastomosis technique appears to be more effective in reducing GER symptoms and preserving gastrointestinal health in patients undergoing proximal gastrectomy for gastric cancer compared to the posterior wall anastomosis technique. These preliminary findings advocate for further research to confirm the benefits and potentially standardize Forearm Anastomosis in surgical practice for gastric cancer.
Clinical effect and prognosis of laparoscopic surgery on colon cancer complicated with intestinal obstruction patients
Authors: Wu Pei-Hua , Ta Zheng-Quan
Published: February 2025

BACKGROUND

Colon cancer is one of the most common malignancies of the digestive tract, often complicated by intestinal obstruction, which can significantly impact patient outcomes. While traditional laparotomy is the standard treatment, it is associated with large wounds, slower recovery, and higher complication rates. Laparoscopic surgery, a minimally invasive approach, may offer better outcomes for these patients.

AIM

To evaluate the clinical effects and prognosis of laparoscopic surgery in patients with colon cancer complicated by intestinal obstruction compared to traditional laparotomy.

METHODS

A retrospective analysis was conducted on 100 patients diagnosed with colon cancer and intestinal obstruction who underwent surgical treatment between January 2020 and December 2022. Patients were divided into two groups: The control group (CG), treated with traditional laparotomy, and the observation group (OG), treated with laparoscopic surgery. Clinical effects, surgical indicators, postoperative pain, inflammatory response, complication rates, quality of life, and prognosis were assessed and compared between the two groups.

RESULTS

The OG showed superior clinical outcomes compared to the CG (P < 0.05). Patients in the OG had shorter operation times, reduced intraoperative blood loss, faster recovery of intestinal function, earlier mobilization, and shorter hospital stays (P < 0.05). Postoperative pain (numerical rating scale scores) and inflammatory markers [tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), C-reactive protein (CRP)] were lower in the OG (P < 0.05). The incidence of complications was significantly reduced in the OG (6.00% vs 22.00%, P < 0.05). Quality of life scores, including physical function, psychological state, social communication, and self-care ability, were significantly higher in the OG (P < 0.05). There were no significant differences between groups in abdominal drainage volume, 1-year tumor recurrence or metastasis rates, or 1- and 3-year survival rates (P > 0.05).

CONCLUSION

The OG showed superior clinical outcomes compared to the CG (P < 0.05). Patients in the OG had shorter operation times, reduced intraoperative blood loss, faster recovery of intestinal function, earlier mobilization, and shorter hospital stays (P < 0.05). Postoperative pain (NRS scores) and inflammatory markers (TNF-α, IL-6, CRP) were lower in the OG (P < 0.05). The incidence of complications was significantly reduced in the OG (6.00% vs 22.00%, P < 0.05). Quality of life scores, including physical function, psychological state, social communication, and self-care ability, were significantly higher in the OG (P < 0.05). There were no significant differences between groups in abdominal drainage volume, 1-year tumor recurrence or metastasis rates, or 1- and 3-year survival rates (P > 0.05).
Advances in management strategies for enteral nutrition-related gastric retention in adult patients with nasogastric tubes
Authors: Feng Li-Fei , Li Xiang-Wei , Zhu Xiao-Qiu , Jin Lin-Na
Published: February 2025

Gastric retention is a common complication in individuals receiving enteral nutrition (EN) via a nasogastric tube, increasing the risk of aspiration pneumonia and causing unnecessary interruptions in nutritional support. Given its clinical significance, establishing effective, evidence-based, and standardized management strategies is essential for bettering patient outcomes and mitigating complications. This review systematically synthesized the diagnostic criteria, assessment methods, influencing factors, management procedures, and intervention strategies for gastric retention in EN patients. Although no universal consensus exists regarding gastric residual volume (GRV) thresholds, evidence indicates that EN can continue at high GRV levels in the absence of gastrointestinal symptoms. Bedside ultrasound emerged as a non-invasive, and precise method GRV assessment, offering potential to standardize clinical practice. Key risk factors for gastric retention include neurological disorders and EN infusion rates exceeding 100 mL/h. Effective management strategies encompass non-pharmacological interventions, pharmacological agents, and traditional Chinese medicine (TCM) therapies. This review underscored the need for integrated, multi-modal management strategies and recommended the adoption of bedside ultrasound and standardized protocols to optimize EN delivery and improve patient outcomes. Large-scale, multicenter clinical trials should be a priority for future investigation to verify the effectiveness of TCM therapies and develop personalized intervention plans for high-risk patients.
High cellular prion protein expression in cholangiocarcinoma: A marker for early postoperative recurrence and unfavorable prognosis
Authors: Shin Dong Woo , Cho Yoon Ah , Moon Sung-Hoon , Kim Tae Hyung , Park Ji-Won , Lee Jung-Woo , Choe Ji-Young , Kim Min-Jeong , Kim Sung-Eun
Published: February 2025

BACKGROUND

The cellular prion protein (PrPC), traditionally associated with neurodegenerative disorders, plays an important role in cancer progression and metastasis by inhibiting apoptosis.

AIM

To investigate the influence of PrPC expression in cholangiocarcinoma (CCA) on patient outcomes following surgical resection.

METHODS

Patients who underwent curative surgical resection for either intrahepatic or hilar CCA were enrolled in this retrospective study. Based on the immunohistochemical staining results of the surgical specimens, patients were categorized into two groups: The low PrPC group (negative or 1+) and the high PrPC group (2+ or 3+). Survival analyses, including overall survival and recurrence-free survival, were conducted using the Kaplan-Meier method and compared using the log-rank test.

RESULTS

In total, seventy-six patients diagnosed with CCA (39 with intrahepatic and 37 with hilar CCA) underwent curative hepatectomy from January 2011 to November 2021. Among these patients, 38 (50%) demonstrated high PrPC expression, whereas the remaining 38 (50%) showed low expression of PrPC. During a median follow-up period of 31.2 months (range: 1 to 137 months), the high PrPC group had a significantly shorter median overall survival than the low PrPC group (40.4 months vs 137.9 months, respectively; P = 0.041). Moreover, the high PrPC group had a significantly shorter median recurrence-free survival than the low PrPC group (13.3 months vs 23.8 months, respectively; P = 0.026).

CONCLUSION

PrPC expression is significantly associated with early recurrence and decreased survival period in CCA patients following surgical resection. Thus, PrPC may be used as a prognostic factor in treatment planning.
Enhancing palliative care in malignant obstructive jaundice: A critical care perspective on endoscopic biliary stenting
Authors: Xie Yun , Xie Hui , Wang Rui-Lan
Published: February 2025

This letter responds to Wang et al 's recent publication on endoscopic biliary stenting for malignant obstructive jaundice (MOJ) by offering constructive feedback and suggestions for future research. We commend the authors for their comprehensive study design and execution, which included a clear delineation of study groups and a robust set of outcome measures. We suggest that future studies incorporate additional biomarkers, such as serum levels of liver enzymes and bilirubin, to provide a more nuanced understanding of liver function changes post-intervention. The study's focus on short-term survival rates is appreciated, but we recommend exploring longer-term follow-up periods to capture the full spectrum of survival outcomes. Additionally, the inclusion of quality of life assessments using validated instruments could offer a more holistic view of patient outcomes. From a critical care perspective, we advocate for the integration of advanced imaging techniques to better characterize biliary anatomy and potentially predict treatment response or complications. We believe that incorporating these suggestions could enhance the understanding of endoscopic biliary stenting's role in MOJ management and its impact on patient outcomes, influencing future clinical guidelines and practice.
Neoadjuvant therapy: Dawn of reducing the high post-surgery recurrence rate of hepatocellular carcinoma
Authors: Zhang Xiao-Dong , Zhang Lu-Yi , Luo Jia-Liang , Yu Ke-Heng , Zhu Ke-Lei
Published: February 2025

The high postoperative recurrence rate remains a major challenge in the treatment of hepatocellular carcinoma (HCC) following resection. Increasing research has been delved into investigating the role of neoadjuvant therapy on the prognosis of resectable HCC. Recent trends in combination therapy with molecularly targeted agents and immune checkpoint inhibitors have significantly improved the efficacy of systemic antitumor treatments, yielding survival benefits exceeding 40%. Neoadjuvant therapy for HCC, whether based on systemic antitumor treatments, locoregional therapies, or their combination, has emerged as a promising research direction. However, there remains a matter of debate on neoadjuvant therapy. In this review, we summarize and discuss the research progress and challenges of neoadjuvant therapy for HCC over the past five years from the perspective of Chinese guidelines to provide new insights and future directions in this field.
Patient selection and operative strategies for laparoscopic intersphincteric resection without diverting stoma
Authors: Hu Gang , Ma Ji , Qiu Wen-Long , Mei Shi-Wen , Zhuang Meng , Xue Jun , Liu Jun-Guang , Tang Jian-Qiang
Published: February 2025

BACKGROUND

Diverting stoma (DS) is routinely proposed in intersphincteric resection for ultralow rectal cancer, but it is associated with increased stoma-related complications and economic burden. Appropriate patient selection and operative strategies to avoid stoma formation need further elucidation.

AIM

To select patients who may not require DS.

METHODS

This study enrolled 505 consecutive patients, including 84 who underwent stoma-free (SF) intersphincteric resection. After matching, patients were divided into SF (n = 78) and DS (n = 78) groups. The primary endpoint was the anastomotic leakage (AL) rate within 6 months and its protective factors for both the total and SF cohorts. The secondary endpoints included overall survival and disease-free survival.

RESULTS

The AL rate was greater in the SF group than in the DS group (12.8% vs 2.6%, P = 0.035). Male sex [(odds ratio (OR) = 2.644, P = 0.021], neoadjuvant chemoradiotherapy (nCRT) (OR = 6.024, P < 0.001), and tumor height from the anal verge ≤ 4 cm (OR = 4.160, P = 0.007) were identified as independent risk factors. Preservation of the left colic artery (LCA) was protective in both the total cohort (OR = 0.417, P = 0.013) and the SF cohort (OR = 0.312, P = 0.027). The female patients who did not undergo nCRT and had preservation of the LCA experienced a significantly lower incidence of AL (2/97, 2.1%). The 3-year overall survival or disease-free survival did not significantly differ between the groups.

CONCLUSION

Female patients who do not receive nCRT may avoid the need for DS by preserving the LCA without increasing the risk of AL or compromising oncological outcomes.
Systematic review and meta-analysis comparing extraperitoneal and transperitoneal routes of colostomy-related complications
Authors: Isah Adamu D , Wang Xu , Shaibu Zakari , Yuan Xiao , Dang Sheng-Chun
Published: February 2025

BACKGROUND

Complications associated with stomas—including parastomal hernia (PSH), prolapse, mucocutaneous separation, and stoma retraction—provide considerable postoperative challenges for colostomy patients. Selecting between extraperitoneal colostomy (EPC) and transperitoneal colostomy (TPC) pathways is therefore essential for mitigating these complications.

AIM

To analyze the existing data regarding the efficacy of EPC compared to TPC in reducing stoma-related complications post-colostomy.

METHODS

PubMed, Google Scholar, EMBASE, MEDLINE, and the Cochrane Library were adopted to uncover pertinent papers in which EPC and TPC approaches were compared. We then conducted a meta-analysis using RevMan 5.4.1.

RESULTS

Both laparoscopic (Lap) and open approaches showed a reduced incidence of PSH in EPC relative to TPC (P < 0.00001 and P = 0.02 respectively). In addition, Lap EPC depicted a lesser incidence of prolapse, mucocutaneous separation, and stoma retraction (P = 0.007, P = 0.03, and P = 0.01, respectively) compared to Lap TPC. However, EPC and TPC did not differ with respect to operation time, blood loss, edema, ischemia, necrosis, or infection after the LAP approach.

CONCLUSION

The extraperitoneal approach may provide benefits in minimizing some stoma-related problems such as PSH, prolapse, mucocutaneous separation, and stoma retraction after colostomy surgery.
Perspectives on Schwann-like cells derived from bone marrow-mesenchymal stem cells: Advancing peripheral nerve injury therapies
Authors: Ferreira Lucas Vinícius de Oliveira , Amorim Rogério Martins
Published: February 2025

Peripheral nerve injuries are clinical conditions that often result in functional deficits, compromising patient quality of life. Given the relevance of these injuries, new treatment strategies are constantly being investigated. Although mesenchymal stem cells already demonstrate therapeutic potential due to their paracrine action, the transdifferentiation of these cells into Schwann-like cells (SLCs) represents a significant advancement in nerve injury therapy. Recent studies indicate that SLCs can mimic the functions of Schwann cells, with promising results in animal models. However, challenges remain, such as the diversity of transdifferentiation protocols and the scalability of these therapies for clinical applications. A recent study by Zou et al provided a comprehensive overview of the role of bone marrow-derived mesenchymal stem cells in the treatment of peripheral nerve injuries. Therefore, we would like to discuss and explore the use of SLCs derived from bone marrow-derived mesenchymal stem cells in more detail as a promising alternative in the field of nerve regeneration.
Kształcenie i praktyka prawnicza Józefa Gidyńskiego w okresie międzywojennym
Authors: Widera Michał
Published: February 2025

Józef Gidyński pochodził z rodziny o wielopokoleniowych tradycjach nauczycielskich. Dzięki decyzji rodziców o przeprowadzce ze Starokrzepic k. Częstochowy do Łodzi uzyskał możliwość kształcenia na poziomie ponadpodstawowym. Mimo zgłoszenia się do służby wojskowej jego ambicją było podjęcie studiów z zakresu prawa. Zamierzenia te udało mu się zrealizować w pierwszych latach II Rzeczypospolitej. Duże zdolności intelektualne i zaangażowanie w pogłębianie wiedzy wpłynęły na uzyskanie przez niego stypendium naukowego i kontynuowanie studiów w Paryżu. W kolejnych latach wykazywał się dużą determinacją w celu uzyskania kwalifikacji do wykonywania kilku zawodów prawniczych, jednak najwięcej satysfakcji dawała mu praktyka adwokacka, którą kontynuował również po wyjeździe do Stanów Zjednoczonych Ameryki, a nawet po przejściu na emeryturę.
Losy Cyganów na ziemi gnieźnieńskiej w XX wieku w świetle dokumentacji władz lokalnych
Authors: Szczepaniak Marek
Published: February 2025

Gniezno i powiat gnieźnieński, mimo iż były jednym z większych skupisk ludności cygańskiej w Wielkopolsce, nie zawsze były uwzględniane w badaniach nad tą ludnością w sposób do tego współmierny. Rzadko też kiedy wykorzystywano przekaz źródłowy materiałów wytworzonych przez lokalne organy administracji państwowej, które przechowywane są w gnieźnieńskim Oddziale Archiwum Państwowego w Poznaniu. Pierwsze przekazy dotyczące pojawiania się Cyganów na terenie Gniezna i okolic pochodzą z okresu pruskiego; liczniejsze, będące efektem działań władz ogólnopaństwowych, z okresu powojennego. Prześledzić w nich można aktywność lokalnych władz będących odpowiedzią na narzuconą odgórnie akcję ewidencjonowania i paszportyzacji ludności cygańskiej, realizowanej pod postacią akcji „C”. Druga grupa przekazów źródłowych powstała w wyniku ogłoszonej w 1964 r. akcji osiedleńczej, której celem było zmuszenie Cyganów do przejścia od koczowniczego do osiadłego trybu życia. Mniej liczne informacje dotyczą działań lokalnych władz. Ilość źródeł pisanych wytworzonych przez gnieźnieńskie urzędy jest niewielka. Jednak na podstawie ich przekazu można stwierdzić, że rodzaj podejmowanych przez tutejszych urzędników działań, podobnie jak w całej Polsce, wynikał z narzucanych odgórnie przez władze centralne akcji, często motywowanych ideologicznie. Pojawiające się w trakcie tych poczynań problemy, próby ich rozwiązywania, a także wywoływane w ten sposób skutki były takie same, jak w innych częściach kraju. Podobne też były reakcje najbardziej zainteresowanych – Cyganów, których zabiegi władz dotyczyły przede wszystkim.
Tadeusza Esmana wspomnienia poznańskie. „Śródka. Moje dzieciństwo i młodość”, cz. 2: Z ciocią Bolesią wśród rodziny i najbliższych sąsiadów
Authors: Bauman Szymon , Esman Janusz
Published: February 2025

Tadeusz Esman pisał wspomnienia w latach 1976–1985, z myślą o przekazaniu wiadomości o swoim dorastaniu dzieciom. Druga część jego wspomnień odnosi się do okresu dzieciństwa i młodości na Śródce w Poznaniu, gdzie urodził się w 1903 r. i przebywał do czasu wyprowadzki w 1927 r. do Bydgoszczy. W tej części jego przeżycia krążą wokół trzech tematów — cioci Bolesi, rodziny i sąsiadów. Wszystkie te aspekty ukazują życie codzienne osób mieszkających na Śródce w tym czasie — dom, warunki życia i pracy, otoczenie przyrody, architektury oraz relacje społeczne. Autor wspomnień opowiada barwnie, dzieli się zapamiętanymi wrażeniami z dzieciństwa, przytacza anegdoty z życia rodzinnego i podwórkowego, tj. z okolicy miejsca zamieszkania na Rynku Śródeckim lub Ostrówku, a także opisuje stosunek do swojej rodziny i sąsiadów.
Księgi protokołów rad pedagogicznych jako źródło do poznania praktyki nauczania (przykład liceów pedagogicznych 1944–1970)
Authors: Młynarczyk-Tomczyk Anita
Published: February 2025

W literaturze naukowej nie wykazano jeszcze znaczenia ksiąg protokołów rad pedagogicznych jako źródła do poznania praktyki nauczania w PRL. Dlatego też tematyka ta wymaga uzupełnienia. Za materiał badawczy przyjęto 43 księgi protokołów rad pedagogicznych liceów pedagogicznych. Zakłady te wypromowały ponad 200 tysięcy absolwentów — nauczycieli szkół podstawowych, którzy uczyli miliony polskich dzieci. Spośród informacji (o zróżnicowanym zastosowaniu naukowym) zawartych w protokołach z posiedzeń rad pedagogicznych wyselekcjonowano te, które z punktu widzenia praktyki nauczania w PRL najczęściej dyskutowano na posiedzeniach rad pedagogicznych: programy nauczania i ich treści, proces nauczania w postaci wykorzystywanych metod i technik kształcenia oraz przekładające się na nie wyniki kształcenia. Ogląd pracy liceów pedagogicznych przez pryzmat tematyki posiedzeń rad pedagogicznych wykazuje, że zgromadzony w nich materiał jest ogromny i powinien się z nim zmierzyć każdy badacz dziejów edukacji w PRL.
Advanced Strategy for Greenhouse Gas Reduction in the Domestic Livestock Sector
Authors: Seo Dongyun , Jo Sangyeol , Kadam Rahul , Jang Heewon , Park Jungyu
Published: February 2025

The livestock sector is essential for food supply and economic benefits, but it emits greenhouse gases during enteric fermentation and livestock manure treatment. This study evaluates carbon neutrality scenarios based on the 2050 NDC and calculates greenhouse gas emissions and reduction potential based on current and projected livestock numbers. Key mitigation strategies include using low-methane feed, reducing nitrogen emissions in manure treatment by decreasing crude protein in feed, and increasing the proportion of energy recovery from pig manure. This study utilizes Tier 1 emission factors from the 1996 IPCC guidelines to assess greenhouse gas reduction and the feasibility of achieving carbon neutrality. Scenario analysis predicts that improving digestion and reducing nitrogen could achieve approximately 1,200 thousand ton-CO2eq in reductions, while an additional reduction of about 600 thousand ton-CO2eq is needed in the manure treatment sector. Improvements in manure treatment methods are essential for achieving carbon neutrality goals. With the increase in domestic meat consumption, livestock numbers are expected to continue to rise. Given key issues such as the reduction of arable land, existing resource recovery methods (such as composting) have limitations. Therefore, improving manure treatment methods is essential for achieving carbon neutrality in the livestock sector, and additional measures, including energy recovery from pig manure and biogas production from cattle manure, are required.