bluuebunny/crossref_metadata_2025 huggingface dataset:
Discussion and Demonstration of RF-MEMS Attenuators Design Concepts and Modules for Advanced Beamforming in the Beyond-5G and 6G Scenario—Part 2
Authors: Tagliapietra Girolamo , Giacomozzi Flavio , Michelini Massimiliano , Marcelli Romolo , Sardi Giovanni Maria , Iannacci Jacopo
Published: July 2024

In this paper, different concepts of reconfigurable RF-MEMS attenuators for beamforming applications are proposed and critically assessed. Capitalizing on the previous part of this work, the 1-bit attenuation modules featuring series and shunt resistors and low-voltage membranes (7–9 V) are employed to develop a 3-bit attenuator for fine-tuning attenuations (<−10 dB) in the 24.25–27.5 GHz range. More substantial attenuation levels are investigated using fabricated samples of coplanar waveguide (CPW) sections equipped with Pi-shaped resistors aiming at attenuations of −15, −30, and −45 dB. The remarkable electrical features of such configurations, showing flat attenuation curves and limited return losses, and the investigation of a switched-line attenuator design based on them led to the final proposed concept of a low-voltage 24-state attenuator. Such a simulated device combines the Pi-shaped resistors for substantial attenuations with the 3-bit design for fine-tuning operations, showing a maximum attenuation level of nearly −50 dB while maintaining steadily flat attenuation levels and limited return losses (<−11 dB) along the frequency band of interest.
Crystallization Sequence of the Spodumene-Rich Alijó Pegmatite (Northern Portugal) and Related Metasomatism on Its Host Rock
Authors: Garate-Olave Idoia , Roda-Robles Encarnación , Santos-Loyola Nora , Martins Tania , Lima Alexandre , Errandonea-Martin Jon
Published: July 2024

The Barroso–Alvão region is an excellent setting for studying Li mineralization associated with granitic pegmatites and developing Li exploration techniques. Among the distinguished pegmatite types in this pegmatite field, the spodumene-bearing dyke from Alijó is a representative example of an Iberian Li–Cs–Ta (LCT) pegmatite currently under exploitation. In this work, we examine the internal evolution of the Alijó dyke and its external metasomatic effect on the surrounding metasediments, contributing to lithium exploration techniques. Electron microprobe analyses provided clues about the crystallization conditions and the degree of differentiation of the pegmatitic melt, whereas the external metasomatism induced by the spodumene-bearing pegmatite was studied through whole-rock geochemistry. The obtained results indicate that the primary crystallization of the studied dyke likely occurred at temperatures between 450–500 °C, with emplacement at shallow crustal levels of about 2–3 kbar. The high concentrations of trace elements such as Li, Cs, Rb, Be, Sn, Nb, Ta, Ge, U, and Tl in the pegmatitic melt suggests high availability of these elements, allowing their partitioning into an early exsolved fluid phase. The exsolution of this fluid phase, subtracting components such as F and B, from the pegmatitic melt would cause a significant undercooling of the melt. Moreover, the interaction of this expelled fluid with the country rock generated a metasomatic overprint in the surrounding metasedimentary host rocks. The metasomatic effect in Alijó is strongly influenced by the nature of the host metasediments, with a significantly higher grade of metasomatism observed in pelitic (mica-rich) samples compared to psammitic (mica-poor) samples collected at same distances from the dyke. The greisen developed close to the pegmatite contact reflects this metasomatic signature, characterized by the mobilization of at least B, F, Li, Rb, Cs, Sn, Be, Nb, Ta, and Tl. We cautiously suggest that whole rock Li concentrations greater than 300 ppm, combined with a minimum value of 1000 ppm for the sum of B, F, Li, Rb, Cs, and Sn in pelitic metasediments of Barroso–Alvão, may be indicative of a mineralized pegmatite in this region.
A Semi-Explicit Algorithm for Parameters Estimation in a Time-Fractional Dual-Phase-Lag Heat Conduction Model
Authors: Lukashchuk Stanislav Yu.
Published: July 2024

This paper presents a new semi-explicit algorithm for parameters estimation in a time-fractional generalization of a dual-phase-lag heat conduction model with Caputo fractional derivatives. It is shown that this model can be derived from a general linear constitutive relation for the heat transfer by conduction when the heat conduction relaxation kernel contains the Mittag–Leffler function. The model can be used to describe heat conduction phenomena in a material with power-law memory. The proposed algorithm of parameters estimation is based on the time integral characteristics method. The explicit representations of the thermal diffusivity and the fractional analogues of the thermal relaxation time and the thermal retardation are obtained via a Laplace transform of the temperature field and utilized in the algorithm. An implicit relation is derived for the order of fractional differentiation. In the algorithm, this relation is resolved numerically. An example illustrates the proposed technique.
Design Strategies of Hydrogen Evolution Reaction Nano Electrocatalysts for High Current Density Water Splitting
Authors: Zang Bao , Liu Xianya , Gu Chen , Chen Jianmei , Wang Longlu , Zheng Weihao
Published: July 2024

Hydrogen is now recognized as the primary alternative to fossil fuels due to its renewable, safe, high-energy density and environmentally friendly properties. Efficient hydrogen production through water splitting has laid the foundation for sustainable energy technologies. However, when hydrogen production is scaled up to industrial levels, operating at high current densities introduces unique challenges. It is necessary to design advanced electrocatalysts for hydrogen evolution reactions (HERs) under high current densities. This review will briefly introduce the challenges posed by high current densities on electrocatalysts, including catalytic activity, mass diffusion, and catalyst stability. In an attempt to address these issues, various electrocatalyst design strategies are summarized in detail. In the end, our insights into future challenges for efficient large-scale industrial hydrogen production from water splitting are presented. This review is expected to guide the rational design of efficient high-current density water electrolysis electrocatalysts and promote the research progress of sustainable energy.
Quality and Quantity of School Lunch in Nanjing: Based on Data from the Sunshine Restaurant Supervision Platform
Authors: Lin Xiaofang , Li Yuanyuan , Wu Qiong , Lv Yizhou , Zhu Yirong , Liu Jingwen , He Le , Wang Zhixu
Published: July 2024

School lunch plays an important role in children’s healthy growth. Previous investigations revealed many problems with school lunches, including unreasonable dietary structure and insufficient micronutrients. This study aimed to assess the dietary structure and nutritional quality of lunches in Nanjing primary and middle schools. A stratified cluster random sampling method was used to select 44 schools that supply lunch in 12 districts in Nanjing, with two primary and two middle schools in each district. Twenty-four primary and twenty middle schools were selected. The Mann–Whitney U test was used to explore the influencing factors. Findings revealed a serious shortage of milk and fruit in school lunches; supply of eggs, fish, shrimp, and shellfish was less than half of the recommended quantity; livestock and poultry supply exceeded the recommended level by over four times. Energy and nutrition intake were suboptimal. Provision of energy, carbohydrates, vitamins (A, B1, B2, and C), calcium, and iron in urban primary schools was significantly higher than that in non-urban primary schools. The same pattern of significantly higher nutrients was equally seen in urban middle schools compared with non-urban middle schools, indicating that food supply was affected by regional economies. Therefore, it is urgent to improve the quality of lunches, with a particular focus on those in non-urban areas.
Comment on Lesser et al. Using Stable Isotope Analyses to Assess the Trophic Ecology of Scleractinian Corals. Oceans 2022, 3, 527–546
Authors: Kahng Samuel E.
Published: July 2024

In warm oligotrophic waters, photosymbiotic coral can flourish across a wide depth range (0–170+ m), extending to depths where light attenuates to ~0.1% of surface values. Conventional wisdom has long assumed that mixotrophic corals must increasingly rely on heterotrophy as the ambient light available to drive photosynthesis decreases with depth. However, evidence challenging this traditional dogma has been accumulating in recent years. Although some evidence suggests that some depth-generalist coral species likely increase their reliance on heterotrophy with increasing depth, there is growing evidence that other species do not. Analysis of bulk stable isotopes (δ13C and δ15N) applied to photosymbiotic corals has been used in several ways to infer their trophic ecology and their relative dependence on symbiont photosynthesis versus heterotrophic feeding. However, metrics based on bulk tissue δ13C and δ15N values are subject to considerable uncertainty due to the multiple factors that can affect their values independent of trophic ecology. These competing factors can be quite challenging to disentangle and have led to inconsistent results and conclusions regarding trends in coral heterotrophy with depth. The evidence to date suggests no uniform trophic pattern with increasing depth or decreasing light. Different corals appear to function differently, which is not surprising given their phylogenetic diversity.
Reply to Kahng, S.E. Comment on “Lesser et al. Using Stable Isotope Analyses to Assess the Trophic Ecology of Scleractinian Corals. Oceans 2022, 3, 527–546”
Authors: Lesser Michael P. , Slattery Marc , Macartney Keir J.
Published: July 2024

Kahng [...]
Monthly Occurrence of Endoparasites of Chaetognaths in a Coastal System of the Mexican Central Pacific
Authors: Plascencia-Palomera Viridiana , Franco-Gordo Carmen , Lozano-Cobo Horacio , Ambriz-Arreola Israel , Suárez-Morales Eduardo , Gómez-Gutiérrez Jaime
Published: July 2024

The prevalence of endoparasites associated with chaetognath abundance in the coastal waters of the Mexican Central Pacific was studied fortnightly from November 2010 to December 2011. A total of 35 (0.21%) out of 16,407 chaetognaths were found to be parasitized. Five out of twelve chaetognath species (Flaccisagitta enflata, F. hexaptera, Parasagitta euneritica, Serratosagitta pacifica, Zonosagitta bedoti) were found to be parasitized by nine endoparasitic taxa: Protists (two morphotypes), digenean metacercariae [Didymozoidae, Hemiuridae, Parahemiurus sp., Lepocreadiidae, Prosorhynchus sp. (Bucephalidae)], and cestodes (metacestodes) [Tetraphyllidea (two morphotypes)]. Parasagitta. euneritica and Z. bedoti were the most abundant chaetognath species, and Protist sp. 2 and Tetraphyllidea sp. 1 were the most abundant parasites. The highest prevalence for most of the endoparasite species occurred in June, and the values varied according to three hydroclimatic periods: stratified (S), semi-mixed (SM), and mixed (M). Eight non-infected chaetognath species, two parasitized chaetognaths (F. enflata and S. pacifica), and two parasites (Protist sp. 1 and Tetraphyllidea sp. 2) were associated with warm temperatures (S and SM periods); in contrast, P. euneritica, Z. bedoti, parasitized F. hexaptera, and the parasite Tetraphyllidea sp. 1 showed a strong local preference for cooler temperatures, high productivity, and high biomass conditions (M periods). We discovered the occurrence of the digenean Prosorhynchus sp. (Bucephalidae) parasitizing the chaetognath P. euneritica, and this is the first report of Prosorhynchus parasitizing chaetognaths worldwide. We also confirmed the presence of Lepocrediidae (metacercariae larval stage) infecting F. hexaptera, a parasite that had only been recorded infecting other chaetognaths of the Atlantic Ocean. The parasite diversity affecting the chaetognath populations of the Central Mexican Pacific coast likely differs between the offshore, outer slope areas, and the surveyed coastal system.
In Silico and In Vitro Studies of Terpenes from the Fabaceae Family Using the Phenotypic Screening Model against the SARS-CoV-2 Virus
Authors: de Sousa Natália Ferreira , Duarte Gabrielly Diniz , Moraes Carolina Borsoi , Barbosa Cecília Gomes , Martin Holli-Joi , Muratov Nail N. , Nascimento Yuri Mangueira do , Scotti Luciana , de Freitas-Júnior Lúcio Holanda Gondim , Filho José Maria Barbosa , Scotti Marcus Tullius
Published: July 2024

In 2019, the emergence of the seventh known coronavirus to cause severe illness in humans triggered a global effort towards the development of new drugs and vaccines for the SARS-CoV-2 virus. These efforts are still ongoing in 2024, including the present work where we conducted a ligand-based virtual screening of terpenes with potential anti-SARS-CoV-2 activity. We constructed a Quantitative Structure–Activity Relationship (QSAR) model from compounds with known activity against SARS-CoV-2 with a model accuracy of 0.71. We utilized this model to predict the activity of a series of 217 terpenes isolated from the Fabaceae family. Four compounds, predominantly triterpenoids from the lupane series, were subjected to an in vitro phenotypic screening in Vero CCL-81 cells to assess their inhibitory activity against SARS-CoV-2. The compounds which showed high rates of SARS-CoV-2 inhibition along with substantial cell viability underwent molecular docking at the SARS-CoV-2 main protease, papain-like protease, spike protein and RNA-dependent RNA polymerase. Overall, virtual screening through our QSAR model successfully identified compounds with the highest probability of activity, as validated using the in vitro study. This confirms the potential of the identified triterpenoids as promising candidates for anti-SARS-CoV-2 therapeutics.
Harnessing Potential of ω-3 Polyunsaturated Fatty Acid with Nanotechnology for Enhanced Breast Cancer Therapy: A Comprehensive Investigation into ALA-Based Liposomal PTX Delivery
Authors: Kumar Rohit , Kumar Anurag , Kumar Dharmendra , Yadav Sneha , Shrivastava Neeraj Kumar , Singh Jyoti , Sonkar Archana Bharti , Verma Pratibha , Arya Dilip Kumar , Kaithwas Gaurav , Agrarwal Ashish Kumar , Singh Sanjay
Published: July 2024

Our hypothesis posited that incorporating alpha-linolenic acid (ALA) into liposomes containing Paclitaxel (PTX) could augment cellular uptake, decrease the therapeutic dosage, and alleviate PTX-related side effects. Our investigation encompassed characterization of the liposomal formulation, encompassing aspects like particle size, surface morphology, chemical structure, drug release kinetics, and stability. Compatibility studies were performed through Fourier transform infrared spectroscopy (FTIR). By utilizing the Box–Behnken design (BBD), we developed ALA-based liposomes with satisfactory particle size and entrapment efficiency. It is noteworthy that ALA incorporation led to a slight increase in particle size but did not notably affect drug entrapment. In vitro drug release assessments unveiled a sustained release pattern, with ALA-PTX liposomes demonstrating release profiles comparable to PTX liposomes. Morphological examinations confirmed the spherical structure of the liposomes, indicating that substituting ALA with phosphatidylcholine did not alter the physicochemical properties. Cellular uptake investigations showcased enhanced uptake of ALA-based liposomes in contrast to PTX liposomes, likely attributed to the heightened fluidity conferred by ALA. Efficacy against MCF-7 cells demonstrated concentration-dependent reductions in cell viability, with ALA-PTX liposomes exhibiting the lowest IC50 value. Morphological analysis confirmed apoptotic changes in cells treated with all formulations, with ALA-PTX liposomes eliciting more pronounced changes, indicative of enhanced anticancer efficacy.
Polyphenols and Phenolic Glucosides in Antibacterial Twig Extracts of Naturally Occurring Salix myrsinifolia (Salisb.), S. phylicifolia (L.) and S. starkeana (Willd.) and the Cultivated Hybrid S. x pendulina (Wender.)
Authors: Salih Enass , Mgbeahuruike Eunice Ego , Prévost-Monteiro Stella , Sipari Nina , Väre Henry , Novak Brigita , Julkunen-Tiitto Riitta , Fyhrqvist Pia
Published: July 2024

(1) Background: Salix species occurring in Finland have not been well studied for their antimicrobial potential, despite their frequent use for lung and stomach problems in traditional medicine. Thus, twig extracts of three species of Salix that are found naturally in Finland and one cultivated species were screened for their antimicrobial properties against human pathogenic bacteria. S. starkeana and S. x pendulina were screened for antibacterial effects for the first time. (2) Methods: An agar diffusion and a microplate method were used for the screenings. Time-kill effects were measured using a plate-count and a microplate method. A DPPH-method using a qualitative TLC-analysis was used to detect antioxidant compounds in antimicrobial extracts. Metabolites from a S. myrsinifolia extract showing good antibacterial effects were identified using UPLC/QTOF-MS. (3) Results: A methanol extract of S. starkeana was particularly active against B. cereus (MIC 625 µg/mL), and a methanol extract of S. myrsinifolia showed good activity against S. aureus and B. cereus (MIC 1250 µg/mL) and showed bactericidal effects during a 24 h incubation of B. cereus. Moreover, a decoction of S. myrsinifolia resulted in good growth inhibition against P. aeruginosa. Our UPLC/QTOF-MS results indicated that proanthocyanidins (PAs), and especially the dimer procyanidin B1 (m/z 577) and other procyanidin derivatives, including highly polymerized proanthocyanidins, were abundant in S. myrsinifolia methanol extracts. Procyanidin B1 and its monomer catechin, as well as taxifolin and p-hydroxycinnamic acid, all present in S. myrsinifolia twigs, effectively inhibited B. cereus (MIC 250 µg/mL). (4) Conclusions: This study indicates that Finnish Salix species contain an abundance of antibacterial condensed tannins, phenolic acids and other polyphenols that deserve further research for the antibacterial mechanisms of action.
Study of the Spectral Characteristics of Crops of Winter Wheat Varieties Infected with Pathogens of Leaf Diseases
Authors: Danilov Roman , Kremneva Oksana , Sereda Igor , Gasiyan Ksenia , Zimin Mikhail , Istomin Dmitry , Pachkin Alexey
Published: July 2024

Studying the influence of the host plant genotype on the spectral reflectance of crops infected by a pathogen is one of the key directions in the development of precision methods for monitoring the phytosanitary state of wheat agrocenoses. The purpose of this research was to study the influence of varietal factors and disease development on the spectral characteristics of winter wheat varieties of different susceptibility to diseases during the growing seasons of 2021, 2022 and 2023. The studied winter wheat crops were represented by three varieties differing in susceptibility to phytopathogens: Grom, Svarog and Bezostaya 100. Over three years of research, a clear and pronounced influence of the varietal factor on the spectral characteristics of winter wheat crops was observed, which in most cases manifested itself as an immunological reaction of specific varieties to the influence of pathogen development. The nature of the influence of the pathogenic background and the spectral characteristics of winter wheat crops were determined by the complex interaction of the development of individual diseases under the conditions of a particular year of research. A uniform and clear division of the spectral characteristics of winter wheat according to the intensity of the disease was recorded only at a level of pathogen development of more than 5%. Moreover, this gradation was most clearly manifested in the spectral channels of the near-infrared range and at a wavelength of 720 nm.
Low-Potassium Fruits and Vegetables: Research Progress and Prospects
Authors: Cui Jiawei , Zhang Yongxue , Zhang Hongmei , Jin Haijun , He Lizhong , Wang Hong , Lu Panling , Miao Chen , Yu Jizhu , Ding Xiaotao
Published: July 2024

With the increasing number of patients with chronic kidney disease (CKD) and the improved recognition of nutritional therapy, research on low-potassium (LK) fruits and vegetables for CKD patients has gained global attention. Despite its already commercial availability primarily in Japan, public awareness remains limited, and cultivation methods lack a comprehensive strategy. This review offers an extensive examination of the developmental significance, current cultivation techniques, and existing limitations of functional LK fruits and vegetables with the objective of providing guidance and inspiration for their exploitation. Additionally, this review investigates various factors influencing K content, including varieties, temperature, light, exogenous substances, harvest time, and harvest parts, with a focus on optimizing production methods to enhance potassium utilization efficiency (KUE) and decrease the K content in plants. Finally, the review outlines the shortcomings and prospects of research on LK fruits and vegetables, emphasizing the importance of interdisciplinary research (in agriculture technology, medicine, and business) for patients with CKD and the future development of this field.
Development of 3D Printable Gelatin Methacryloyl/Chondroitin Sulfate/Hyaluronic Acid Hydrogels as Implantable Scaffolds
Authors: Murphy Caroline A. , Serafin Aleksandra , Collins Maurice N.
Published: July 2024

The development of biomaterials tailored for various tissue engineering applications has been increasingly researched in recent years; however, stimulating cells to synthesise the extracellular matrix (ECM) is still a significant challenge. In this study, we investigate the use of ECM-like hydrogel materials composed of Gelatin methacryloyl (GelMA) and glycosaminoglycans (GAG), such as hyaluronic acid (HA) and chondroitin sulphate (CS), to provide a biomimetic environment for tissue repair. These hydrogels are fully characterised in terms of physico-chemical properties, including compression, swelling behaviour, rheological behaviour and via 3D printing trials. Furthermore, porous scaffolds were developed through freeze drying, producing a scaffold morphology that better promotes cell proliferation, as shown by in vitro analysis with fibroblast cells. We show that after cell seeding, freeze-dried hydrogels resulted in significantly greater amounts of DNA by day 7 compared to the GelMA hydrogel. Furthermore, freeze-dried constructs containing HA or HA/CS were found to have a significantly higher metabolic activity than GelMA alone.
Economic and Technical Assessing the Hybridization of Solar Combined Cycle System with Fossil Fuel and Rock Bed Thermal Energy Storage in Neom City
Authors: Akroot Abdulrazzak , Al Shammre Abdullah Sultan
Published: July 2024

Rising energy demands, the depletion of fossil fuels, and their environmental impact necessitate a shift towards sustainable power generation. Concentrating solar power (CSP) offers a promising solution. This study examines a hybridization of a combined cycle power plant (CCPP) based on solar energy with fossil fuel and energy storage in rock layers to increase Saudi Arabia’s electricity production from renewable energy. The fuel is used to keep the temperature at the inlet of the gas turbine at 1000 °C, ensuring the power produced by the Rankine cycle remains constant. During the summer, the sun is the main source of power generation, whereas in the winter, reliance on fuel increases significantly. The Brayton cycle operates for 10 h during peak solar radiation periods, storing exhaust heat in rock beds. For the remaining 14 h of the day, this stored heat is discharged to operate the Rankine steam cycle. Simulations and optimizations are performed, and the system is evaluated using a comprehensive 4E analysis (energy, exergy, exergoconomic, and environmental) alongside a sustainability assessment. A parametric evaluation examines the effect of key factors on system performance. The rock bed storage system compensates for solar intermittency, enabling power generation even without sunlight. The study reveals that the system generated 12.334 MW in June, achieving an energy efficiency of 37% and an exergy efficiency of 40.35%. The average electricity cost during this period was 0.0303 USD/kWh, and the carbon footprint was 0.108 kg CO2/kWh. In contrast, during January, the system produced 13.276 MW with an energy efficiency of 37.91% and an exergy efficiency of 44.16%. The average electricity cost in January was 0.045 USD/kWh, and the carbon footprint was 0.1 kg CO2/kWh. Interestingly, solar energy played a significant role: it contributed 81.42% of the heat in June, while in January, it accounted for 46.77%. The reduced electricity costs during June are primarily attributed to the abundant sunshine, which significantly powered the system.
Temporal Evaluation of a Minimally Invasive Method of Preimplantation Genetic Testing for Aneuploidy (mi-PGT-A) in Human Embryos
Authors: Phillips Katharine R. B. , Kuzma-Hunt Alexander G. , Neal Michael S. , Lisle Connie , Sribalachandran Hariharan , Carter Ronald F. , Amin Shilpa , Karnis Megan F. , Faghih Mehrnoosh
Published: July 2024

Preimplantation genetic testing for aneuploidy (PGT-A) has become a useful approach for embryo selection following IVF and ICSI. However, the biopsy process associated with PGT-A is expensive, prone to errors in embryo ploidy determination, and potentially damaging, impacting competence and implantation potential. Therefore, a less invasive method of PGT-A would be desirable and more cost-effective. Noninvasive methods for PGT-A (ni-PGT-A) have been well-studied but present limitations in terms of cf-DNA origin and diagnostic accuracy. Minimally invasive pre-implantation genetic testing (mi-PGT-A) for frozen-thawed embryo transfer is a promising, less studied approach that utilizes a combination of spent culture media (SCM) and blastocoelic fluid (BF)-derived cell-free (CF)-DNA for genetic testing. This study aimed to optimize the effectiveness of mi-PGT-A for aneuploidy diagnosis by investigating the optimal temporal sequence for this protocol. SCM+BF was collected at either 48 or 72 h of culture after thawing day 3 preimplantation embryos. cf-DNA in the SCM+BF was amplified, analyzed by next-generation sequencing (NGS) and compared with results from the corresponding whole embryos (WEs) obtained from human embryos donated for research. Fifty-three (42 expanded blastocysts, 9 early blastocysts, and 2 morula) WE and SCM+BF samples were analyzed and compared. The overall concordance rate between SCM+BF and WE was 60%. Gender and ploidy concordance improved with extended culture time from 48 h (73% and 45%) to 72 h (100% and 64%), respectively. These results demonstrate that SCM+BF-derived cf-DNA can be successfully used for mi-PGT-A. Our findings indicate that longer embryo culture time prior to SCM+BF-derived cf-DNA analysis improves DNA detection rate and concordance with WEs and decreases the proportion of false positive results.
Prevalence of Irritable Bowel Syndrome in Ankylosing Spondylitis and Its Association with Clinical and Demographic Findings and Gut Pathology
Authors: Ferdous Nira , Rasker Johannes J. , Akhter Shabnam , Kamruzzaman Md. , Islam Md. Nazrul
Published: July 2024

Irritable bowel syndrome (IBS) is common in ankylosing spondylitis (AS) and may be associated with the disease. We aimed to determine the prevalence of IBS in AS patients and its association with clinical and demographic patient characteristics and with macroscopic and microscopic gut lesions. Sixty consecutive AS patients were included in this study. Disease activity was assessed with the BASDAI (Bath Ankylosing Spondylitis Disease Activity Index) and functional status with the BASFI (Bath Ankylosing Spondylitis Functional Index). The ROME III criteria were used to diagnose IBS. Macroscopic lesions were graded during colonoscopies. Biopsy specimens were taken from the terminal ileum, colon (ascending, transverse and descending) and rectum. Histological samples were scored with Cuvelier grading. The prevalence of IBS was 23.3% (14/60). The mean age of 14 IBS subjects (10 male) was 32 ± 8.50., with a higher BASDAI (p = 0.046). Macroscopic lesions were more frequent in IBS cases in the terminal ileum (46.2% vs. 34.9%), ascending colon (21.4% vs. 2.2%) and rectum (21.4% vs. 17.4%), with Grade 2 significantly more prevalent in the ascending colon (p = 0.03). Microscopic lesions did not differ among the IBS-present and -absent groups. In conclusion, the prevalence of IBS was high in AS patients and associated with higher disease activity. Grade 2 macroscopic lesions were more frequent in the ascending colon.
Enhancing Identification of Meteorological and Biological Targets Using the Depolarization Ratio for Weather Radar: A Case Study of FAW Outbreak in Rwanda
Authors: Maniraguha Fidele , Vodacek Anthony , Kim Kwang Soo , Ndashimye Emmanuel , Rushingabigwi Gerard
Published: July 2024

Leveraging weather radar technology for environmental monitoring, particularly the detection of biometeors like birds, bats, and insects, presents a significant challenge due to the dynamic nature of their behavior. Unlike hydrometeor targets, biometeor targets exhibit arbitrary changes in direction and position, which significantly alter radar wave polarization upon scattering. This study addresses this challenge by introducing a novel methodology utilizing Rwanda’s C-Band Polarization Radar. Our approach exploits the capabilities of dual-polarization radar by analyzing parameters such as differential reflectivity (ZDR) and correlation coefficient (RHOHV) to derive the Depolarization Ratio (DR). While existing radar metrics offer valuable insights, they have limitations in fully capturing depolarization effects. To address this, we propose an advanced fuzzy logic algorithm (FL_DR) integrating the DR parameter. The FL_DR’s performance was rigorously evaluated against a standard FL algorithm. Leveraging a substantial dataset comprising nocturnal clear air radar echoes collected during a Fall Armyworm (FAW) outbreak in maize fields from September 2020 to January 2021, the FL_DR demonstrated a notable improvement in accuracy compared to the existing FL algorithm. This improvement is evident in the Fraction of Echoes Correctly Identified (FEI), which increased from 98.42% to 98.93% for biological radar echoes and from 87.02% to 95.81% for meteorological radar echoes. This enhanced detection capability positions FL_DR as a valuable system for monitoring, identification, and warning of environmental phenomena in regions similar to tropical areas facing FAW outbreaks. Additionally, it could be tested and further refined for other migrating biological targets such as birds, insects, or bats.
Ranging Offset Calibration and Moving Average Filter Enhanced Reliable UWB Positioning in Classic User Environments
Authors: Liu Junhao , Gao Zhouzheng , Li Yan , Lv Siao , Liu Jia , Yang Cheng
Published: July 2024

With the rapid development of the Internet of Things (IoT), the positioning accuracy requirement of the IoT is increasing, especially for those applications without Global Navigation Satellite System (GNSS) signals. Ultra-Wideband (UWB) is treated as a high-accuracy positioning method that can be utilized in GNSS-blocked environments. However, UWB’s performance is still limited when it is applied in practical applications due to errors such as Non-Line-of-Sight (NLOS) errors, multipath errors, and systematic errors in UWB range values. To constrain the impacts of these mentioned errors on UWB positioning accuracy, this work proposes a novel UWB positioning model by introducing a UWB ranging offset calibration algorithm and a moving average filter into a robust extended Kalman filter. In such a UWB positioning model, the ranging offset calibration algorithm is employed to limit the infuence of UWB systematic errors, and the prior residual-based IGG-III weighting model is used to restrain the impacts of NLOS and multipath errors. The moving average filter is to further decrease the impact of the measuring noise on UWB positioning parameter estimation. To investigate the effectiveness of this proposed method, three sets of UWB experiments are arranged in three classic user environments. The experimental results show that (1) after applying the UWB ranging offset calibration algorithm, UWB positioning accuracies in classic environments, namely indoor condition, outdoor condition, and transition area are increased by 50.3%, 20.2%, and 46.9%, respectively; (2) the moving average filter can effectively improve the smoothness of UWB positioning results in terms of standard deviation; (3) the prior residual-based robust theory brings about 49.4% and 25.2% positioning improvements to horizontal and vertical components under poor measurement quality conditions, but such improvements are rather slight when there are good-quality measurements; and (4) after applying the ranging offset calibration algorithm and moving average filter to the robust EKF together, the elevation accuracy of UWB positioning is increased by 67.1%, 22.2%, and 50.5%, respectively, in the three classic user environments.
Quad-Band 1 × 4 Linear MIMO Antenna for Millimeter-Wave, Wearable and Biomedical Telemetry Applications
Authors: Tiwari Rakesh N. , Malya K. Geetha , Nandini Girigari , Nikhitha P. Baby , Sharma Deepti , Singh Prabhakar , Kumar Pradeep
Published: July 2024

In this paper, we present the design of a millimeter-wave 1 × 4 linear MIMO array antenna that operates across multiple resonance frequency bands: 26.28–27.36 GHz, 27.94–28.62 GHz, 32.33–33.08 GHz, and 37.59–39.47 GHz, for mm-wave wearable biomedical telemetry application. The antenna is printed on a flexible substrate with dimensions of 11.0 × 44.0 mm2. Each MIMO antenna element features a modified slot-loaded triangular patch, incorporating ‘cross’-shaped slots in the ground plane to improve impedance matching. The MIMO antenna demonstrates peak gains of 6.12, 8.06, 5.58, and 8.58 dBi at the four resonance frequencies, along with a total radiation efficiency exceeding 75%. The proposed antenna demonstrates excellent diversity metrics, with an ECC < 0.02, DG > 9.97 dB, and CCL below 0.31 bits/sec/Hz, indicating high performance for mm-wave applications. To verify its properties under flexible conditions, a bending analysis was conducted, showing stable S-parameter results with deformation radii of 40 mm (Rx) and 25 mm (Ry). SAR values for the MIMO antenna are calculated at 28.0/38.0 GHz. The average SAR values for 1 gm/10 gm of tissues at 28.0 GHz are found to be 0.0125/0.0079 W/Kg, whereas, at 38.0 GHz, average SAR values are 0.0189/0.0094 W/Kg, respectively. Additionally, to demonstrate the telemetry range of biomedical applications, a link budget analysis at both 28.0 GHz and 38.0 GHz frequencies indicated strong signal strength of 33.69 dB up to 70 m. The fabricated linear MIMO antenna effectively covers the mm-wave 5G spectrum and is suitable for wearable and biomedical applications due to its flexible characteristics.
Wireless and Battery-Free Sensor for Interstitial Fluid Pressure Monitoring
Authors: Qian Chengyang , Ye Fan , Li Junye , Tseng Peter , Khine Michelle
Published: July 2024

Congestive heart failure (CHF) is a fatal disease with progressive severity and no cure; the heart’s inability to adequately pump blood leads to fluid accumulation and frequent hospital readmissions after initial treatments. Therefore, it is imperative to continuously monitor CHF patients during its early stages to slow its progression and enable timely medical interventions for optimal treatment. An increase in interstitial fluid pressure (IFP) is indicative of acute CHF exacerbation, making IFP a viable biomarker for predicting upcoming CHF if continuously monitored. In this paper, we present an inductor-capacitor (LC) sensor for subcutaneous wireless and continuous IFP monitoring. The sensor is composed of inexpensive planar copper coils defined by a simple craft cutter, which serves as both the inductor and capacitor. Because of its sensing mechanism, the sensor does not require batteries and can wirelessly transmit pressure information. The sensor has a low-profile form factor for subcutaneous implantation and can communicate with a readout device through 4 layers of skin (12.7 mm thick in total). With a soft silicone rubber as the dielectric material between the copper coils, the sensor demonstrates an average sensitivity as high as –8.03 MHz/mmHg during in vitro simulations.
Adherent Peanut Image Segmentation Based on Multi-Modal Fusion
Authors: Wang Yujing , Ye Fang , Zeng Jiusun , Cai Jinhui , Huang Wangsen
Published: July 2024

Aiming at the problem of the difficult segmentation of adherent images due to the not fully convex shape of peanut pods, their complex surface texture, and their diverse structures, a multimodal fusion algorithm is proposed to achieve a 2D segmentation of adherent peanut images with the assistance of 3D point clouds. Firstly, the point cloud of a running peanut is captured line by line using a line structured light imaging system, and its three-dimensional shape is obtained through splicing and combining it with a local surface-fitting algorithm to calculate a normal vector and curvature. Seed points are selected based on the principle of minimum curvature, and neighboring points are searched using the KD-Tree algorithm. The point cloud is filtered and segmented according to the normal angle and the curvature threshold until achieving the completion of the point cloud segmentation of the individual peanut, and then the two-dimensional contour of the individual peanut model is extracted by using the rolling method. The search template is established, multiscale feature matching is implemented on the adherent image to achieve the region localization, and finally, the segmentation region is optimized by an opening operation. The experimental results show that the algorithm improves the segmentation accuracy, and the segmentation accuracy reaches 96.8%.
Efficiency Improvement for Chipless RFID Tag Design Using Frequency Placement and Taguchi-Based Initialized PSO
Authors: Le Cong-Cuong , Dao Trung-Kien , Pham Ngoc-Yen , Nguyen Thanh-Huong
Published: July 2024

Frequency encoding chipless Radio Frequency Identification (RFID) tags have been frequently using the radar cross section (RCS) parameter to determine the resonant frequencies corresponding to the encoded information. Recent advancements in chipless RFID design have focused on the generation of multiple frequencies without considering the frequency position and signal amplitude. This article proposes a novel method for chipless RFID tag design, in which the RCS response can be located at an exact position, corresponding to the desired encoding signal spectrum. To achieve this, the empirical Taguchi method (TM), in combination with particle swarm optimization (PSO), is used to automatically search for optimal design parameters for chipless RFID tags with a fast response time, to comply with the frequency encoding requirements in the presence of the mutual coupling effect. The proposed design method is validated using I-slotted chipless tag structures that are fabricated and measured with different sets of resonant frequencies.
Assessing the Post-Activation Performance Enhancement of Upper Limbs in Basketball Athletes: A Sensor-Based Study of Rapid Stretch Compound and Blood Flow Restriction Training
Authors: Cui Shuang , Du Zhihao , Wang Nannan , Zhang Xiuli , Li Zongquan , Zhang Yanping , Wang Liang
Published: July 2024

Objective: This study introduces a novel methodology combining rapid stretch compound training with blood flow restriction (BFR) to investigate post activation performance enhancement (PAPE) in basketball players, a field that has been predominantly explored for lower limbs. We aimed to assess the efficacy of this combined approach on upper limb muscle performance in athletes. Methods: We employed a randomized, self-controlled crossover trial with ten male basketball players. The bench press throw (BPT) served as the primary metric, with players undergoing four interventions post-baseline: (1) STR—plyometric training; (2) BFR—blood flow restriction; (3) COMB—STR integrated with BFR; and (4) CON—control. Innovatively, we utilized an intelligent tracking sensor to precisely measure peak power (PP), peak velocity (PV), mean power (MP), and mean velocity (MV) at 4, 8, and 12 min post-intervention, providing a detailed temporal analysis of PAPE. Results: The COMB intervention demonstrated superior PAPE effects at 4 min, significantly outperforming STR and BFR alone and the control group across all measured indices (p < 0.05). Notably, the COMB group maintained these improvements for PV, PP, and H up to 12 min post-intervention, suggesting a prolonged effect. Conclusion: (1) The COMB stimulation has been shown to successfully induce PAPE more effectively than STR and BFR modality alone. (2) It appears that the optimal effects of PAPE are achieved within 4 min of exercising under this COMB. By the 12 min mark, only the COMB group continued to show significant improvements in PV, PP, and H compared to both the baseline and the CON group, while the effects in the STR and BFR groups further diminished. This suggests that although the PAPE effect is maintained over time, its optimal performance may peak at the 4 min mark and then gradually weaken as time progresses.
Silica Wort Supplementation as an Alternative for Yeast Stress Relief on Corn Ethanol Production with Cell Recycling
Authors: Oliveira Matheus Ribeiro Barbosa , Douradinho Rafael Soares , Sica Pietro , Mota Layna Amorim , Pinto Alana Uchôa , Faria Tamires Marques , Baptista Antonio Sampaio
Published: July 2024

In very high gravity (VHG) fermentation, yeast cells are subjected to a multitude of challenging conditions, including the osmotic pressure exerted by the high sugar content of the wort and the stress factors associated with the high ethanol concentrations present at the end of the fermentation cycle. The response of this biological system to abiotic stresses may be enhanced through biochemical and physiological routes. Silica may play a significant role in regulating the cellular homeostasis of yeast. Alternatively, it is expected that this outcome may be achieved through biochemical responses from the effects of vitamins on yeast cells and the physiological yeast route changing by the culture medium aeration. The objective of this study was to investigate the effects of adding 500 mg L−1 of silica on corn ethanol wort medium and the possibility of supplementing the same wort with vitamins alongside aeration (0.2 v v−1 min−1) as an alternative resource to sustain the fermentation yield rather than adding silica in a fed-batch fermentation cycle with yeast recycling. Upon completion of the five fermentation cycles, yeast samples subjected to the treatment with the addition of silica exhibited a 3.1% higher fermentation yield in comparison to the results observed in the vitamins plus aeration medium bath. Even though greater biomass production (19.1 g L−1) was observed through aerobic yeast behavior in vitaminized supplemented corn medium, the provided silica had a more beneficial effect on yeast stress relief for very high gravity fermentation in a corn hydrolyzed wort with cell recycling.
Impact of Employee Environmental Concerns on Sustainable Practices: Investigating Organizational Commitment and Job Satisfaction
Authors: Cao Shengjie , Xu Pengjie , Qalati Sikandar Ali , Wu Ke
Published: July 2024

Environmental issues are gradually increasing due to increases in carbon emissions, overproduction, plastic use, the burning of fossil fuels, etc. Therefore, ecological sustainability is a primary concern for society and the upcoming generation. Considering this, the present research objective is to examine the factors influencing employee eco-friendly behavior (EEBH) and firm environmental performance (FEP). Cross-sectional data were accumulated from 403 employees working in casual dining restaurants in China and analyzed through partial least squares structural equation modeling (PLS–SEM) approaches (i.e., PLS algorithm, bootstrapping, blindfolding, and PLS prediction). The findings support the significant effect of environmental concern (ENVC) on employee organizational commitment (EOC), employee job satisfaction (EJoS), and EEBH. In addition, EOC and EJoS directly and indirectly influence EEBH. Furthermore, EOC also mediates the link between ENVC and EJoS. Finally, the findings also show that EEBH stimulates environmental performance. By showing the links between these elements, it has been emphasized that EEBH is a precondition of good organizational productivity and how it contributes to enhancing the EJoS and overall firm’s health. It challenges managers to create a work environment that is conducive to sustainability for improved customer relations and a strong reputation for the organization in society.
Optimal Design of Truss Structures for Sustainable Carbon Emission Reduction in Korean Construction
Authors: Lee Donwoo , Kim Jeonghyun , Lee Seungjae
Published: July 2024

Due to the recent abnormalities in global temperature and increasing carbon emissions, the world is working to reduce carbon emissions. In particular, the construction sector accounts for about 37% of all carbon emissions, so it is one of the areas where sustainable reduction efforts must be made. Therefore, in this paper, an optimal design process was performed by evaluating carbon emissions as the objective function, a choice which differed from the objective function of the existing research used in the optimal design of truss structures. The metaheuristics algorithm used for the process was the advanced crow search algorithm. The levels of carbon emissions generated when the material of a truss structure consisted of a customary material (steel) were compared to scenarios in which timber was used, and a construction scenario centered on the Republic of Korea was established for comparison. The structures used as examples were 10-, 17-, 22-, and 120-bar truss structures. As a result, it was confirmed that truss structures using timber had fewer carbon emissions than structures using steel. In addition, it was confirmed that, even in the same timber structures, domestic timber had fewer carbon emissions than imported timber. These results confirmed that in order to achieve carbon neutrality in the construction field, carbon emissions must be considered in advance, in the design stage.