bluuebunny/crossref_metadata_2025 huggingface dataset:
Integrated Analysis of DNA Methylome and Transcriptome Reveals Epigenetic Regulation of Cold Tolerance in Litopenaeus vannamei
Authors: Zhu Weilin , Yang Chunling , Liu Qingyun , Peng Min , Li Qiangyong , Wang Huanling , Chen Xiuli , Zhang Bin , Feng Pengfei , Chen Tiancong , Zeng Digang , Zhao Yongzhen
Published: July 2023

DNA methylation is an important epigenetic modification that has been shown to be associated with responses to non-biological stressors. However, there is currently no research on DNA methylation in response to environmental signals in shrimp. In this study, we conducted a comprehensive comparative analysis of DNA methylation profiles and differentially expressed genes between two strains of Litopenaeus vannamei with significantly different cold tolerance through whole genome bisulfite sequencing (WGBS) and transcriptome sequencing. Between Lv-C and Lv-T (constant temperature of 28 °C and low temperatures of 18 °C and 10 °C) under cytosine-guanine (CG) environments, 39,100 differentially methylated regions (DMRs) were identified, corresponding to 9302 DMR-related genes (DMRGs). The DMRs were mainly located in the gene body (exons and introns). Gene Ontology (GO) analysis showed that these DMRGs were significantly enriched in cell parts, catalytic activity, and metabolic processes. Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed significant enrichment of these DMRGs in pathways such as proteasome (ko03050), oxidative phosphorylation (ko00190), mTOR signaling pathway (ko04150), fatty acid metabolism (ko01212), and fatty acid degradation (ko00071). The comprehensive results suggested that L. vannamei mainly regulates gene expression in response to low temperatures through hypermethylation or demethylation of some genes involved in thermogenesis, glycolysis, the autophagy pathway, the peroxisome, and drug metabolism pathways. These results provide important clues for studying DNA methylation patterns and identifying cold tolerance genes in shrimp.
Design of Mathematical Model and Selected Coefficient Specifications for Composite Materials Reinforced with Fabric from Waste Tyres
Authors: Hrehova Stella , Knapčíková Lucia
Published: July 2023

Polyvinyl butyral (PVB) is a thermoplastic resin commonly used as an interlayer material in laminated glass. Combined with textile fibres from worn tyres, PVB can produce a composite material with unique properties. One such property is absorption. Absorption in textile fibre composite materials refers to the ability of the material to absorb or retain moisture or other fluids. The presence of moisture or liquids can affect the properties of composite materials, such as their strength, stiffness, and dimensional stability. As a result of the physical and chemical action of the environment, corrosion of plastics occurs and manifests itself in changes in appearance, surface quality, weight, dimensions, and also in changes in other properties. This paper investigates four composite materials with different fabrics content. The aim of this paper is to propose a generalized mathematical model for absorption values so that, with different ratios of textile fibre in the material, its quality indicators are at a sufficient level. Our study will proceed from the assumption that by changing the values of the individual coefficients of the selected model based on their analysis, we will achieve the required qualitative indicators.
Effect of Portland Cement on the Selected Properties of Flue Gas Desulfurization Gypsum-Based Plasters
Authors: Baran Edyta , Hynowski Mariusz , Kotwica Łukasz , Rogowski Jacek
Published: July 2023

The introduction of the European Union’s climate change legislation and the intended use of renewable energy sources instead of fossil fuels will significantly reduce the production of flue gas desulfurization (FGD) gypsum used as the raw material for gypsum mortar plasters’ production. This has forced mortar producers to look for alternative materials, including gypsum–cement composites. This work investigated the mechanical strength and linear extension of four gypsum–cement mortars with the gypsum content reduced to 30%. The authors showed that the cement admixture of 6 to 12% introduced into the prepared mortars resulted in the formation of gypsum–cement mortars, which fulfill the requirements of the EN 13279-1:2008 standard concerning mechanical strength. This publication took into account the use of scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), and X-ray diffractometry to characterize the chemical and phase composition of the mortars up to 180 days of dry air curing and increased relative humidity (RH) conditions. The formation of thaumasite, ettringite, and mixed ettringite–thaumasite phases was interesting because of their deleterious effect on the durability of plaster mortars.
Association of Fish Oil Supplementation with Risk of Coronary Heart Disease in Individuals with Diabetes and Prediabetes: A Prospective Study in the UK Biobank
Authors: Liu Xiaohui , Li Yin , Wan Xuzhi , Zhuang Pan , Wu Yuqi , Zhang Lange , Ao Yang , Yao Jianxin , Zhang Yu , Jiao Jingjing
Published: July 2023

This study aimed to explore the association between habitual intake of fish oil supplementation and the risk of developing CHD in patients with prediabetes and diabetes. Habitual use of fish oil was assessed by repeated questionnaires. Cox proportional hazard models were applied to calculate hazard ratios (HRs) and 95% confidence intervals (CIs). Over a median follow-up of 11.6 years, 4304 and 3294 CHD cases were documented among 47,663 individuals with prediabetes and 22,146 patients with diabetes in the UK Biobank, respectively. After multivariable adjustment, the HRs (95% CI) of CHD were 0.91 (0.85–0.98) and 0.87 (0.80–0.95) for individuals utilizing fish oil supplementation compared with non-users among the participants with prediabetes and diabetes, respectively. Furthermore, we identified an inverse relationship between fish oil use and CHD incidence, which was significantly mediated by serum C-reactive protein (CRP) levels in individuals with prediabetes and by very-low-density lipoprotein cholesterol (VLDL-C) in patients with diabetes at baseline. The inverse associations were consistent in the analyses stratified by potential confounders. In conclusion, the consumption of fish oil supplements was linked to decreased serum CRP and VLDL-C levels and subsequent CHD risk among adults with prediabetes and diabetes. Our findings highlight the important role of the habitual intake of fish oil supplements in preventing CHD in individuals with impaired glucose metabolism.
Application of Quality by Design Principles to the Development of Oral Lyophilizates Containing Olanzapine
Authors: Bjelošević Žiberna Maja , Ahlin Grabnar Pegi
Published: July 2023

Oral lyophilizates are intended for application to the oral cavity or for dispersing in water. The purposes of this research were: (i) to set up the quality by design approach in the development of oral lyophilizates for drug incorporation; and (ii) to evaluate the established approach by comparing its outcomes with experimentally obtained results. Within the knowledge space, properties about drugs, excipients, and the lyophilization process were acquired, followed by the determination of critical quality attributes via risk identification. Risks were assessed by failure mode and effective analysis, which recognized critical material attributes, i.e., type, concentration, particle size, solubility of drug and excipients, while as main critical process parameters, cooling rate, shelf temperature, and chamber pressure during drying were pointed out. Additionally, design space was established using the Minitab® 17 software and valued with an 88.69% coefficient of determination. A detailed comparison between the model and experimental results revealed that the proposed optimal compositions match in the total concentration of excipients (6%, w/w) in the pre-lyophilized liquid formulation, among which mannitol predominates. On the other hand, a discrepancy regarding the presence of gelatin was detected. The conclusion was that the set model represents a suitable onset toward optimization of drug-based oral lyophilizates development, preventing unnecessary investment of time and resources.
Editorial on Special Issue “Lipid Nanosystems for Local Drug Delivery”
Authors: Catita José , Lopes Carla M.
Published: July 2023

Nanosystems provide an attractive approach to pharmacological therapy, with the possibility of enhancing the performance and overcoming the constraints of conventional therapies, thus adding substantial value to some of the already available formulations [...]
The Transimmanence of the Real: Ontological Pluralism in the School of Ibn ʻArabī
Authors: Iyer Bharatwaj
Published: July 2023

This paper studies the concept of “ontological pluralism”, developed by Heidegger scholar Iain Thomson, in relation to the waḥdat al-wujūd framework of Ibn ʻArabī’s school. Heidegger’s ontological difference between being and entities, and the definition of being in excess of any particular entitative determination, calls for an ethic of pluralism and acceptance of the myriad ways in which being is encountered and understood. In my paper, this pluralism—and its conceptual foundation on the meaning and reality of being—is developed further through Ibn ʻArabī’s complex distinction and interpenetration between the Real’s transcendence (tanzīh) and immanence (tashbīh). The pluralistic and polysemic possibilities of this Akbarian “transimmanence” is compared with Heideggerian ontological pluralism, using Milad Milani’s recent Heideggerian approach to the study of Sufism. This comparison asks if elements of a robust pluralism cannot be found in an avowedly premodern metaphysical framework like that of Ibn ʻArabī, thereby attempting to trouble the uniqueness of the critical breaks in the history of modern Western thought. An attempt to develop a decolonial approach to the study of pluralism sees waḥdat al-wujūd and its later development not just as an object of historical analysis but as a theoretical framework that can positively inform our political and ethical concerns. This is why this paper brings together Heideggerian and Akbarian approaches to pluralism in their own terms. This combined conceptual framework is then used to bring to light the Akbarian pluralism in the life, death, and writings of subcontinental Sufis like Dārā Shikōh and Sarmad Kāshānī.
The Relationship of Time Span and Missing Data on the Noise Model Estimation of GNSS Time Series
Authors: Sun Xiwen , Lu Tieding , Hu Shunqiang , Huang Jiahui , He Xiaoxing , Montillet Jean-Philippe , Ma Xiaping , Huang Zhengkai
Published: July 2023

Accurate noise model identification for GNSS time series is crucial for obtaining a reliable GNSS velocity field and its uncertainty for various studies in geodynamics and geodesy. Here, by comprehensively considering time span and missing data effect on the noise model of GNSS time series, we used four combined noise models to analyze the duration of the time series (ranging from 2 to 24 years) and the data gap (between 2% and 30%) effects on noise model selection and velocity estimation at 72 GNSS stations spanning from 1992 to 2022 in global region together with simulated data. Our results show that the selected noise model have better convergence when GNSS time series is getting longer. With longer time series, the GNSS velocity uncertainty estimation with different data gaps is more homogenous to a certain order of magnitude. When the GNSS time series length is less than 8 years, it shows that the flicker noise and random walk noise and white noise (FNRWWN), flicker noise and white noise (FNWN), and power law noise and white noise (PLWN) models are wrongly estimated as a Gauss–Markov and white noise (GGMWN) model, which can affect the accuracy of GNSS velocity estimated from GNSS time series. When the GNSS time series length is more than 12 years, the RW noise components are most likely to be detected. As the duration increases, the impact of RW on velocity uncertainty decreases. Finally, we show that the selection of the stochastic noise model and velocity estimation are reliable for a time series with a minimum duration of 12 years.
Toward a High-Resolution Wave Forecasting System for the Changjiang River Estuary
Authors: Jiang Yan , Rong Zengrui , Li Yiguo , Li Cheng , Meng Xin
Published: July 2023

Based on a high-resolution unstructured SWAN model and GFS forecast wind, an operational wave forecasting system is conducted for the Changjiang River Estuary (CRE). The performance of the wave forecasting system is evaluated by comparing it with the altimeter observations and in situ wave buoys. The present operational system shows good accuracy in reproducing the seasonal and the synoptic-scale wave characteristics over the CRE. The forecasting capability in three different horizons, including 24 h, 48 h, and 72 h forecasts, is evaluated. Waves over the CRE exhibit distinct seasonal variability. Larger waves occur in both the summer and winter when typhoons and cold weather events affect the CRE. In contrast, waves with longer wave periods take place mainly in the wind transition seasons, i.e., the spring and fall, and the wave directions are more dispersed in these seasons. A seasonal varied forecasting capability is also revealed: better in the winter and spring than in the summer and fall and better during cold weather events than during typhoons. A cross comparison with the model analysis suggests that there is a systematic difference between wave measurements by Jason-3 and Sentinel-3A/3B. The significant wave height from Jason-3 compares best with the model analysis and forecasts and is systematically lower than Sentinel-3A/3B in lower wave conditions (<4 m) in the East China Sea. Substantial discrepancies exist among the three altimeters when the significant wave height exceeds 4 m, and further efforts are needed to discern their merits.
TactiGraph: An Asynchronous Graph Neural Network for Contact Angle Prediction Using Neuromorphic Vision-Based Tactile Sensing
Authors: Sajwani Hussain , Ayyad Abdulla , Alkendi Yusra , Halwani Mohamad , Abdulrahman Yusra , Abusafieh Abdulqader , Zweiri Yahya
Published: July 2023

Vision-based tactile sensors (VBTSs) have become the de facto method for giving robots the ability to obtain tactile feedback from their environment. Unlike other solutions to tactile sensing, VBTSs offer high spatial resolution feedback without compromising on instrumentation costs or incurring additional maintenance expenses. However, conventional cameras used in VBTS have a fixed update rate and output redundant data, leading to computational overhead.In this work, we present a neuromorphic vision-based tactile sensor (N-VBTS) that employs observations from an event-based camera for contact angle prediction. In particular, we design and develop a novel graph neural network, dubbed TactiGraph, that asynchronously operates on graphs constructed from raw N-VBTS streams exploiting their spatiotemporal correlations to perform predictions. Although conventional VBTSs use an internal illumination source, TactiGraph is reported to perform efficiently in both scenarios (with and without an internal illumination source) thus further reducing instrumentation costs. Rigorous experimental results revealed that TactiGraph achieved a mean absolute error of 0.62∘ in predicting the contact angle and was faster and more efficient than both conventional VBTS and other N-VBTS, with lower instrumentation costs. Specifically, N-VBTS requires only 5.5% of the computing time needed by VBTS when both are tested on the same scenario.
A 3D Anisotropic Thermomechanical Model for Thermally Induced Woven-Fabric-Reinforced Shape Memory Polymer Composites
Authors: Wang Yingyu , Wang Zhiyi , Ma Jia , Luo Chao , Fang Guangqiang , Peng Xiongqi
Published: July 2023

Soft robotic grippers offer great advantages over traditional rigid grippers with respect to grabbing objects with irregular or fragile shapes. Shape memory polymer composites are widely used as actuators and holding elements in soft robotic grippers owing to their finite strain, high specific strength, and high driving force. In this paper, a general 3D anisotropic thermomechanical model for woven fabric-reinforced shape memory polymer composites (SMPCs) is proposed based on Helmholtz free energy decomposition and the second law of thermodynamics. Furthermore, the rule of mixtures is modified to describe the stress distribution in the SMPCs, and stress concentration factors are introduced to account for the shearing interaction between the fabric and matrix and warp yarns and weft yarns. The developed model is implemented with a user material subroutine (UMAT) to simulate the shape memory behaivors of SMPCs. The good consistency between the simulation results and experimental validated the proposed model. Furthermore, a numerical investigation of the effects of yarn orientation on the shape memory behavior of the SMPC soft gripper was also performed.
An Asymmetric Encryption-Based Key Distribution Method for Wireless Sensor Networks
Authors: Cheng Yuan , Liu Yanan , Zhang Zheng , Li Yanxiu
Published: July 2023

Wireless sensor networks are usually applied in hostile areas where nodes can easily be monitored and captured by an adversary. Designing a key distribution scheme with high security and reliability, low hardware requirements, and moderate communication load is crucial for wireless sensor networks. To address the above objectives, we propose a new key distribution scheme based on an ECC asymmetric encryption algorithm. The two-way authentication mechanism in the proposed scheme not only prevents illegal nodes from accessing the network, but also prevents fake base stations from communicating with the nodes. The complete key distribution and key update methods ensure the security of session keys in both static and dynamic environments. The new key distribution scheme provides a significant performance improvement compared to the classical key distribution schemes for wireless sensor networks without sacrificing reliability. Simulation results show that the proposed new scheme reduces the communication load and key storage capacity, has significant advantages in terms of secure connectivity and attack resistance, and is fully applicable to wireless sensor networks.
The Process Analysis Method of SAR Target Recognition in Pre-Trained CNN Models
Authors: Zheng Tong , Li Jin , Tian Hao , Wu Qing
Published: July 2023

Recently, attention has been paid to the convolutional neural network (CNN) based synthetic aperture radar (SAR) target recognition method. Because of its advantages of automatic feature extraction and the preservation of translation invariance, the recognition accuracies are stronger than traditional methods. However, similar to other deep learning models, CNN is a “black-box” model, whose working process is vague. It is difficult to locate the decision reasons. Because of this, we focus on the process analysis of a pre-trained CNN model. The role of the processing to feature extraction and final recognition decision is discussed. The discussed components of CNN models are convolution, activation function, and full connection. Here, the convolution processing can be deemed as image filtering. The activation function provides a nonlinear element of processing. Moreover, the fully connected layers can also further extract features. In the experiment, four classical CNN models, i.e., AlexNet, VGG16, GoogLeNet, and ResNet-50, are trained by public MSTAR data, which can realize ten-category SAR target recognition. These pre-trained CNN models are processing objects of the proposed process analysis method. After the analysis, the content of the SAR image target features concerned by these pre-trained CNN models is further clarified. In summary, we provide a paradigm to process the analysis of pre-trained CNN models used for SAR target recognition in this paper. To some degree, the adaptability of these models to SAR images is verified.
Optimal Control of Semi-Active Suspension for Agricultural Tractors Using Linear Quadratic Gaussian Control
Authors: Ahn Da-Vin , Kim Kyeongdae , Oh Jooseon , Seo Jaho , Lee Jin Woong , Park Young-Jun
Published: July 2023

In this study, a semi-active suspension based on a hydro-pneumatic mechanism was designed to minimize the ride vibration using a suspension control algorithm. The performance of the algorithm was critical for controlling the characteristics of the target tractor. A linear-quadratic-Gaussian (LQG) optimal control algorithm was designed as a semi-active suspension control algorithm. The plant model for developing this algorithm was based on the parameters of an actual tractor. The rear suspension deflection was represented by a Kalman-filter-based state observer feedback to estimate the state variables that were difficult to measure. The designed state observer of the LQG controller was validated in terms of an accuracy index. The estimated vertical velocity and acceleration accuracies of the cabin were 83% and 79%, respectively. The performance of the designed controller was validated in terms of a performance index by comparing the performance of a tractor equipped with a rear rubber mount with that of one equipped with a semi-active suspension. The peak and root-mean-square values of the vertical acceleration of the cabin were reduced by up to 48.97% and 47.06%, respectively. This study could serve as a basis for the application of the control algorithm to systems with similar characteristics, thereby reducing system costs.
Thermal Performance Assessment of Lightweight Aggregate Concrete by Different Test Methods
Authors: Gomes Maria da Glória , Bogas José Alexandre , Real Sofia , Moret Rodrigues António , Machete Rita
Published: July 2023

Structural lightweight aggregate concrete is currently an alternative to normal-weight concrete when thermal insulation properties are required to meet the objectives of energy efficiency and sustainability. The accurate evaluation of the thermal performance is thus essential for designing structural lightweight concrete elements. This paper aims to evaluate the thermal behavior of structural lightweight aggregate concrete, assessed through different tests methods. To this end, a vast experimental campaign was carried out involving specimens produced with several types of lightweight aggregate and different water/cement ratios. The thermal performance was established by thermal conductivity, which was determined according to a modified transient pulse method and a quasi-stationary method, and specific heat capacity, which was determined through a transient pulse method and a heat transfer method. Normal-weight concrete was also tested for comparison purposes. Experimental evidence showed that lightweight aggregate concretes with lower density are associated with up to about 50% lower thermal conductivity and higher specific heat capacity than normal-weight concrete. Moreover, the study demonstrated that the expeditious transient pulse method is suitable for assessing the thermal conductivity of this type of concrete, and that both the transient pulse method and the heat transfer method are adequate to determine the specific heat capacity.
Potential of Integrated Nutrient Management to Rehabilitate the Dieback-Affected Mango Cultivar Sammer Bahisht Chaunsa
Authors: Bibi Fatma , Hameed Asifa , Muhammad Noor , Shahzad Khurram , Ahmad Iftikhar , Shah Tawaf Ali , Z. Gaafar Abdel-Rhman , Hodhod Mohamed S. , Bourhia Mohammed , Nafidi Hiba-Allah
Published: July 2023

The mango cultivar Summer Bahisht (SB) Chaunsa is the most sensitive and susceptible to dieback disease among other cultivars. Despite the environmental variables, low nutritional value contributes to the drastic prevalence of the disease. Therefore, it was hypothesized that providing balanced nutrition through an integrated nutrient approach could rehabilitate plants affected by dieback disease. Treatments were NPK at the recommended dose (control), NPK + farmyard manure, NPK + press mud, NPK + poultry litter, and NPK + city effluent, and NPK + sulfur. Sulfur was applied at 3 kg per plant, while the organic amendments were applied at 100 kg per plant NPK was applied at the recommended dose per square feet of tree canopy. Leaf samples were taken 5 months after treatment application. Results were analyzed through two-way ANOVA analysis using R statistical language software. Although the disease recovery rate was slow and we did not find any plant that recovered one year after treatment application, the reduction in disease was prominent in the treatment where poultry litter + NPK was applied. The poultry litter with the recommended NPK treatment showed 20% and 50% reductions in disease intensity in the 2nd and 3rd years of the experiment, respectively, as compared to NPK alone.
A Demand Forecasting Strategy Based on a Retrofit Architecture for Remote Monitoring of Legacy Building Circuits
Authors: Fernandes Rubens A. , Gomes Raimundo C. S. , Costa Carlos T. , Carvalho Celso , Vilaça Neilson L. , Nascimento Lennon B. F. , Seppe Fabricio R. , Torné Israel G. , da Silva Heitor L. N.
Published: July 2023

Energy demand forecasting is crucial for planning and optimizing the use of energy resources in building facilities. However, integrating digital solutions and learning techniques into legacy buildings presents significant challenges due to limited or outdated resources, hampering predictive analytics in these buildings and their circuits. To fill this gap, this article proposes an innovative demand forecasting strategy using an AIoT retrofit architecture based on the SmartLVGrid metamodel. This architecture allows remote monitoring of legacy building circuits, facilitating the collection, processing and storage of data in the cloud. We use several learning algorithms, including linear regression, support vector regressor, random forest regressor, XGBoost regressor, and long short-term memory (LSTM) neural network, to predict energy demand 15 min ahead, identifying potential overruns of contracted demand in accordance with Brazilian regulations. After Bayesian optimization, the LSTM neural network outperformed other models for most of the selected datasets and detected 32 out of 38 demand overruns on the test set. XGBoost and random forest followed closely, detecting 30 demand overruns. Overall, our cost-effective solution optimizes energy usage and efficiently mitigates potential demand exceedances in building installations. This is achieved through a step-by-step approach to upgrading existing aging facilities, which promotes energy efficiency and sustainability.
The Government’s Environmental Attention and the Sustainability of Environmental Protection Expenditure: Evidence from China
Authors: Sun Jing , Hu Jienan , Wang Hongmei , Shi Yinfeng , Wei Ziru , Cao Tangzhe
Published: July 2023

Transformation to a green economy depends on long-term, continuous government financial investments in the environmental protection field. This study used the budget and final accounts of provincial environmental protection expenditure in China from 2007 to 2019 to establish a two-way fixed-effects model to verify the impact of government attention on environmental protection expenditure. The sustainability of Chinese local governments’ environmental protection expenditure is weak, and the fluctuations conform to the punctuated equilibrium characteristics. Fluctuations in government attention have a significant positive impact on changes in fiscal environmental protection expenditure, and the characteristics of campaign governance are relatively obvious. Fiscal transparency can strengthen the relationship between government attention and the environmental protection expenditure budget; however, the adjustment effect on the final accounts of environmental protection expenditure, which depend more on the budget implementation process, is not significant. To improve the effectiveness of environmental governance, government departments must pay long-term and sustained attention to environmental issues, improve the transparency of the implementation process of environmental protection expenditure budgets, strengthen the role of public supervision, and ensure investment in environmental governance.
Visco-Elastic Interface Effect on the Dynamic Stress of Symmetrical Tunnel Embedded in a Half-Plane Subjected to P Waves
Authors: Jin Hexin , Liu Xiaomin , Zhou Junlong
Published: July 2023

A semi-analytical method is developed to study the visco-elastic interface effect on the dynamic stress of a non-circular symmetrical tunnel in a half-plane subjected to P waves, and the interaction between the visco-elastic interface around the tunnel and the traction free boundary at the half-plane is analyzed. The complex variable function method combined with the wave function expansion method is introduced to obtain the theoretical expressions of waves around the non-circular tunnel. To satisfy the traction-free boundary condition at the half-plane, the large circle assumption is applied. The expanded coefficients are determined by using appropriate boundary conditions with stiffness parameters and viscosity coefficients of the interface. Selected numerical results are presented, and the interface effect on the dynamic stress under different embedded depths is discussed. It is found that the interacting effect of the visco-elastic interface and the traction-free boundary is quite related with the wave frequency. Comparison with existing results is also given to validate the semi-analytical method.
Identification of Markers Associated with Wheat Dwarf Virus (WDV) Tolerance/Resistance in Barley (Hordeum vulgare ssp. vulgare) Using Genome-Wide Association Studies
Authors: Soleimani Behnaz , Lehnert Heike , Trebing Sarah , Habekuß Antje , Ordon Frank , Stahl Andreas , Will Torsten
Published: July 2023

Wheat dwarf virus (WDV) causes an important vector transmitted virus disease, which leads to significant yield losses in barley production. Due to the fact that, at the moment, no plant protection products are approved to combat the vector Psammotettix alienus, and this disease cannot be controlled by chemical means, the use of WDV-resistant or -tolerant genotypes is the most efficient method to control and reduce the negative effects of WDV on barley growth and production. In this study, a set of 480 barley genotypes were screened to identify genotypic differences in response to WDV, and five traits were assessed under infected and noninfected conditions. In total, 32 genotypes showed resistance or tolerance to WDV. Subsequently, phenotypic data of 191 out of 480 genotypes combined with 34,408 single-nucleotide polymorphisms (SNPs) were used for a genome-wide association study to identify quantitative trait loci (QTLs) and markers linked to resistance/tolerance to WDV. Genomic regions significantly associated with WDV resistance/tolerance in barley were identified on chromosomes 3H, 4H, 5H, and 7H for traits such as relative virus titer, relative performance of total grain weight, plant height, number of ears per plant, and thousand grain weight.
Biodiesel Production Directly from Rapeseeds
Authors: Tanner Amanda , Baranek Morgan , Eastlack Taylor , Butts Brian , Beazley Melanie , Hampton Michael
Published: July 2023

Rapeseeds are desirable as feedstock for manufacturing biodiesel due to their high production capacity and oil yield. The standard production of biodiesel from rapeseeds is a lengthy process including multiple time-consuming steps, and the method is not environmentally friendly because of the large energy requirements, the use of high volumes of organic solvents and water, and the need for a catalyst, which must be captured, purified, and recycled. In this study, we report a method to produce biodiesel in a single mechanical step directly from intact rapeseeds without adding a catalyst. The process is more environmentally friendly as there is less need for water than in current industrial processes, and it reduces pollutants from organic solvents, catalysts, and wastewater. Additionally, the remaining biomass shows adsorption characteristics for metals, potentially making it useful in water remediation.
Understanding Cassiopea andromeda (Scyphozoa) Invasiveness in Different Habitats: A Multiple Biomarker Comparison
Authors: Thé Jorge , Mammone Marta , Piraino Stefano , Pennetta Antonio , De Benedetto Giuseppe , Garcia Tatiane , de Oliveira Soares Marcelo , Rossi Sergio
Published: July 2023

A dual nutrition mode (i.e., mixotrophy) can be advantageous for alien species in a new environment. In Cearà (Brazil), the symbiotic jellyfish Cassiopea andromeda is rapidly spreading under diverse environmental conditions across natural and human-altered coastal habitats, such as mangroves and shrimp farms. Here we report on the trophic ecology of the alien upside-down jellyfish sampled in these two contrasting coastal habitats during the dry (July–October) and rainy (January–April) seasons, investigated by means of organic biomarkers (lipids, carbohydrates) and bulk tissue stable isotope (δ15N and δ13C) analyses. Total lipid content of jellyfish gonads was generally higher in shrimp farms, whereas no significant difference in carbohydrate concentration was found in jellyfish tissues from the two different habitats. Similarly, there were no significant differences in the δ15N values of jellyfish tissues from the two contrasting habitats, whereas the δ13C values were higher in jellyfish from shrimp farms. Overall, the higher carbon-enriched value in aquaculture ponds supports the hypothesis of differences of available food sources compared to the natural mangrove habitats, where food availability exhibits a stronger seasonality. In fact, aquaculture ponds are characterized by human-driven regular food supply, leading to more stable trophic conditions and to enhanced growth, lipid production, and gonadal output of C. andromeda jellyfish. This investigation may contribute to predicting how Cassiopea mixotrophy may contribute to explaining its differential success in different habitats.
Hubungan Demensia Dengan Tingkat Kemandirian Activity Of Daily Living (ADL) Pada Lansia Di RT.04 RW.11 Jati Bening Pondok Gede Bekasi
Authors: Nurlan Nurlan , Eny Kusdiah
Published: July 2023

Dementia can affect the ability of daily activities because it is influenced by a collection of existing symptoms such as decreased cognitive function, changes in mood, and behavior. People with dementia in addition to experiencing gradual cognitive weakness, will also experience a decline in daily activities (Activity Of Daily Living / ADL). RW 11 Jatibening Pondok Gede Bekasi. Total population is 53 respondents. Samples were taken with a total sampling technique of 53 respondents. The analysis used univariate and bivariate using chi-square with =5%. The results of the study found that there was a relationship between dementia and the level of independence in Activity Of Daily Living (ADL) in the elderly at RT 04 RW 11 Jatibening Pondok Gede Bekasi. The conclusion is that the elderly who experience dementia in the category of mild intellectual impairment are  people 30 (56.6%), the level of independence of the elderly in fulfilling the Activity Of Daily Living (ADL) in the category of mild dependence is 33 people (62.3%), and there is a relationship between There is a significant relationship between dementia and the level of independence of Activity Of Daily Living (ADL) in the Elderly In RT 04 RW 11 Jatibening Pondok Gede Bekasi. It is hoped that this research can provide information to the elderly with dementia so that they can continue to train their memory, as well as provide information to their families. so that it can provide motivation to family members in helping the elderly in meeting the needs of Activity Of Daily Living (ADL).
PENGARUH TERAPI MUROTTAL SURAT AR-RAHMAN TERHADAP PERUBAHAN TEKANAN DARAH PADA LANSIA DENGAN HIPERTENSI DI POSYANDU SEDAP MALAM DUA JATI CEMPAKA PONDOK GEDE BEKASI
Authors: Meilita Zuhriya
Published: July 2023

Memasuki usia tua fungsi fisiologis menurun, sehingga tubuh mengalami kerentanan terhadap berbagai penyakit. Salah satu penyakit yang paling populer di kalangan lanjut usia yakni tekanan darah tinggi (hipertensi). Penatalaksanaan non farmakologi untuk menurunkan stres dan meningkatkan perasaan rileks pada lansia hipertensi yang mempengaruhi tekanan darah, yaitu dengan relaksasi, mengaji, maupun terapi murottal surat Ar-Rahman. Tujuan penelitian ini untuk mengetahui pengaruh terapi murottal surat Ar-Rahman terhadap perubahan tekanan darah pada lansia dengan hipertensi di Posyandu Sedap Malam Dua Jti Cempaka Pondok Gede Bekasi. Metode penelitian yang digunakan adalah Pre Eksperimen dengan pendekatan one group pre test-post test design. Penelitian ini diikuti oleh 30 responden dengan hipertensi. Pengumpulan data dengan mengukur tekanan darah sebelum dan sesudah dilakukan terapi murottal surat Ar-Rahman sebanyak 7 kali dalam 1 minggu. Hasil penelitian analisis univariat dan bivariat menggunakan uji Paired Samples T-Test. Hasil penelitian munujukkan rata-rata tekanan sistol dan diastol sebelum terapi murottal surat Ar-Rahman adalah sistol 148,33 mmHg dan diastol 90,73 mmHg, sesudah terapi murottal surat Ar-Rahman adalah sistol 123,00 mmHg dan diastol 77,53 mmHg. Hasil uji Paired Samples T-Test menunjukkan tekanan darah sistol dan diastol nilai Sig. (2-tailed) 0,000 < 0,05. Simpulan penelitian ini ada pengaruh antara penerapan terapi murottal surat ar-rahman terhadap perubahan tekanan darah pada lansia dengan hipertensi di Posyandu Sedap Malam 2 Jati Cempaka Pondok Gede Bekasi. Saran untuk peneliti selanjutnya agar hasil penurunan tekanan darah lebih valid dapat menambahkan kelompok kontrol dan alat terkalibrasi dengan akurat.

Kata kunci : Hipertensi, Lansia, Surat Ar-Rahman, Terapi Murottal.
Dynamic Modeling and Analysis of Electrodynamic Multi-tether System
Authors: Li Xialin , Yang Keying , Li Lincheng , Yao Fuzhen
Published: July 2023

Electrodynamic tether (EDT) is a key prospective technique for space-debris removal without the use of propellant. However, there are 2 main shortcomings of the classical EDT system. One is that the conductive tether with a single wire should exceed several kilometers to produce the expected force, which increases the risk of collision and damage. The other is the heavy current or high voltage caused by the overlong tether, which may even melt itself. Therefore, a novel electrodynamic multi-tether (EMT) system has been proposed here to overcome the above disadvantages of the classical EDT system. The EMT system has multi tethers connecting the 2 end bodies, which has more complex dynamic behaviors than the EDT system. In order to promote the application of the EMT system, this paper will pay attention to the dynamic modeling and analysis of the EMT system, to reveal the primary dynamic characteristics. Firstly, the dynamic equation of the novel EMT system was established. Secondly, the linear assumption and vibration theory were utilized to illustrate its primary dynamic characteristic. Finally, the expressions of the vibration period and critical current of tether were given and numerical simulations were conducted to verify these analyses. The results showed that the tether libration equation can be simplified when the size of main satellite is much smaller than that of tether. Besides, the tether will go tumbling immediately when the practical current exceeds the critical current.
FOOD DELIVERY SERVICE: THE EFFECTS OF PERCEIVED QUALITY, PERCEIVED EASE OF USE AND PERCEIVED VALUE TOWARDS CUSTOMER SATISFACTION
Authors: Alden Sperico Michael , Rosshahpudin Nur Shuhadah , Tarmazi Siti Anis Adilah , Sulaiman Suria , Mohd Ali Najua
Published: July 2023

Consumers and distributors have benefited from the food industry just as much as food producers have. Nowadays, an online food delivery system is essential due to recent advances in the industry and the increased internet usage. Understanding the key success factors that contribute to sustainable growth and profitability in this space is essential for businesses looking to succeed in this rapidly evolving market. While there are many benefits to ordering food online, there are also several issues that need to be addressed. The objective of this study is to determine the critical success factors of the online food delivery service towards customer satisfaction. Total of 306 people that have experienced using the online food delivery system were surveyed from January till May 2022, and questionnaire were analysed by using the SPSS. Findings show that perceived quality, perceived ease of use and perceived value have positive relationship towards customer satisfaction. It is seen as opportunities for service providers to reap the benefits of recurring earnings from consumers by providing fast delivery, good meals, and fair promotions.
Metode Ijtihad Syafi’iyyah Oriented dalam Pemikiran Ekonomi Islam Ulama Banjar (Studi Kitab Sabîl Al-Muhtadîn, Mabâdî ‘Ilm Al-Fiqh, Risâlah Mu’âmalât)
Authors: Sauqi Muhammad , Rusydi Akhmad , Masruddin Masruddin
Published: July 2023

Penelitian ini dilatarbelakangi oleh adanya pemikiran ulama Banjar dalam kitab Sabîl Al-Muhtadîn, Mabâdî ‘Ilm Al-Fiqh dan Risâlah Mu’âmalât yang membahas tentang konsep ekonomi Islam. Pemikiran tersebut tidaklah muncul begitu saja, melainkan dipengaruhi oleh orientasi mazhab syafi’i yang melatarbelakangi intelektual mereka. Berdasarkan fenomena di atas, maka penelitian ini menganalisis secara mendalam tentang bagaimana konsep serta metode ijtihad Syafi’iyyah Oriented ulama Banjar dalam kitab Sabîl Al-Muhtadîn, Mabâdî ‘Ilm Al-Fiqh dan Risâlah Mu’âmalât yang berhubungan dengan ekonomi Islam. Penelitian ini sangat penting, mengingat problematika hukum ekonomi Islam yang semakin berkembang. Sehingga studi terhadap kitab-kitab fikih ulama Banjar merupakan kegiatan yang relevan untuk mencari formulasi baru dalam mengatasi problematika hukum yang berhubungan dengan ekonomi Islam. Metode yang digunakan menurut jenisnya adalah kajian pustaka (library research) dengan pendekatan sejarah dan metode istinbath hukum. Sedangkan sumber data adalah kitab Sabîl Al-Muhtadîn, Mabâdî ‘Ilm Al-Fiqh dan Risâlah Mu’âmalât. Hasil penelitian menunjukkan bahwa pertama, konsep ekonomi Islam dalam kitab Sabîl Al-Muhtadîn, Mabâdî ‘Ilm Al-Fiqh dan Risâlah Mu’âmalât yaitu membahas tentang zakat produktif, zakat uang kertas, gadai mengguanakn akad jual putus, jual beli mu’athath. Kedua, metode ijtihad yang berorientasi kepada mazhab syafi’i dapat diketahui dengan analisis terhadap teks dalam pemikiran mereka yang mengikuti pendapat ulama syafi’iyyah (qauli) dan menghubungkan pendapat ulama syafi’iyyah dengan kondisi pada zamannya (ilhaqi) serta menggunakan metode ijtihad melalui quran, hadis, qiyas, urf dan maslahah mursalah. Sehingga pemikiran ekonomi Islam ulama Banjar dalam kitab Sabîl Al-Muhtadîn, Mabâdî ‘Ilm Al-Fiqh dan Risâlah Mu’âmalât perlu diberikan apresiasi dan bisa menjadi inspirasi bagi para akademisi dalam melakukan fatwa terhadap permasalahan ekonomi yang selalu berkembang dari masa ke masa.
THE ROLE OF HYPERBARIC OXYGENATION IN TREATMENT OF NEUROLOGICAL CAUSES OF CHRONIC PAIN IN HUMANS: SCOPING REVIEW
Authors: Priyal Priyal , Mohan Chaudhari Dinesh , N Renjen Pushpendra , Mishra Anjali , Sahu Neelam , Bhatnagar Arushee
Published: July 2023

Hyperbaric oxygenation or hyperbaric oxygen therapy (HBOT) has a spectrum of applications in the clinical setting. It is used non-empirically in pain management, hypoxic encephalopathy and critical post-cardiac arrest care. Clinical outcome improvement varies case-by-case. We reviewed the literature for etiologies of neurological causes of chronic pain and role of HBOTin the management of chronic pain in these conditions
Language in Waiting for Godot
Authors: عطيوي غانم عبيد
Published: July 2023

Language is what determines the regulated world, the signification of which provides the foundation of our culture, our activities and our relations. It defines our identity as a form of reassurance. It deals not only with the impossibilities of knowing the motivation of human beings, but also presents the problem of communication between human beings. Speech is, undoubtedly, the proof of existence as well as a manner of contending silence, solitude and death, and it is man’s unique heritage.Absurd dramatists’ use of language probes the limitations of language both as a means of communication and as an instrument of thought as there can be no definite meanings in a world deprived of values, principles and virtues. They have chosen to write in a language devoid of content to become the adequate representation of stagnant life; they present language as an inefficient tool to express one’s thought, to comprehend the world, or to define one’s self. So, Becket materialized the absurdity of modern life and human condition in his play.
Miocardiopatía periparto, una enfermedad poco frecuente con manifestaciones usuales: a propósito de dos casos
Authors: Ospino-Guzmán Jessica Liliana , Ospino-Guerra María Clara , Restrepo-Marín Juan David , Morales-Díaz Esteban Andrés , Cano Rivera Rodolfo
Published: July 2023

La miocardiopatía periparto es una forma rara de insuficiencia cardíaca caracterizada por disfunción sistólica ventricular izquierda que se presenta al final del embarazo o en los meses siguientes al parto. Su incidencia se estima en 1 de cada 1 000 a 4 000 partos según registros estadounidenses, con una alta mortalidad en la población africana. Se desconoce su causa exacta, pero se han propuesto diversas teorías fisiopatológicas; su diagnóstico se basa en las manifestaciones clínicas y la exclusión de otras causas de insuficiencia cardíaca y aunque en general su pronóstico es bueno, una pequeña proporción de mujeres puede presentar insuficiencia cardíaca crónica y complicaciones tromboembólicas. Presentamos dos casos de miocardiopatía periparto que debutaron con disnea y tuvieron un curso usual de la enfermedad. Destacamos el proceso diagnóstico y plan terapéutico basado en las últimas guías disponibles según la revisión de la literatura, lo que favoreció el buen desenlace clínico de ambas pacientes.
EFEITOS ADVERSOS DOS QUIMIOTERÁPICOS NA CAVIDADE ORAL
Authors: Novais de Castro Karolina , Dias de Medeiros Letícia , Pereira Claudio
Published: July 2023

Introdução:  O câncer é um grupo de doenças que, em comum, possuem o desenvolvimento atípico das células; é a segunda principal causa de mortes no mundo. Dentre os recursos terapêuticos, os quimioterápicos se destacam, porém, eles atuam concomitantemente tanto em células neoplásicas como nas saudáveis. Objetivo: descrever os principais efeitos adversos causados pelos quimioterápicos na cavidade oral e demonstrar a atuação do Cirurgião-Dentista para prevenção e tratamento destas alterações bucais. Materiais e Métodos: revisão bibliográfica, utilizando bases de dados e artigos provenientes das bibliotecas virtuais, Scielo, PubMed e Google Acadêmico, bem como livros de referência na área do presente estudo. Discussão e Conclusão: As alterações bucais mais comuns são a mucosite, xerostomia, infecções fúngicas, infecções herpéticas, a neurotoxicidade, trombocitopenia, disgeusia e disfagia. O cirurgião-dentista irá intervir em prol da redução das complicações causadas pelos quimioterápicos, Mesmo o Cirurgião-Dentista não sendo o principal responsável pelo tratamento, ele é de suma importância no diagnóstico e tratamento dos sintomas orais.