bluuebunny/crossref_metadata_2025 huggingface dataset:
Riesgo cardiometabólico en usuarios aparentemente sanos del primer nivel de atención en un distrito del Callao, Perú
Authors: Morales Juan , Basilio-Rojas Marlene Raquel
Published: October 2022

Objetivos: Determinar el riesgo cardiometabólico en usuarios aparentemente sanos de un establecimiento de salud del primer nivel de la Región Callao. Materiales y métodos: Estudio descriptivo transversal. La población estuvo conformada por usuarios de los servicios del Centro de Salud Mi Perú, se incluyeron a personas mayores de 18 años aparentemente sanos que recibieron evaluación preventiva para detectar enfermedades no transmisibles. La muestra incluyó a 245 usuarios de ambos sexos, evaluados en el segundo semestre del 2019. Se realizó el análisis documental de las historias clínicas. Resultados: Del total de participantes, el 76,3% (n=187) era de sexo femenino, el 49% (n=120) perteneciente al grupo de edad de 30 a 60 años y 42% (n=103) mayores de 60 años. Según el índice de masa corporal, el 30,6% (n=75) tenía sobrepeso y el 44,9% (n=110) obesidad, la mayoría correspondiente a obesidad clase I. De la muestra, el 63,9% (n=99) tenían muy alto riesgo cardiometabólico y el 16,8% (n=26) alto riesgo. Del grupo con muy alto riesgo cardiometabólico, el 88,9% (n=88) correspondió al sexo femenino, mientras que en el grupo de alto riesgo, el 65,4% (n=17) eran mujeres (p<0,001). Así mismo, el 96% (n=95) de los sujetos con muy alto riesgo y 65,4% (n=17) de los que tienen alto riesgo presentaron exceso de peso (p<0,001). Conclusiones: En los usuarios que recibieron atención preventiva en el primer nivel de atención, existe una elevada frecuencia de alto riesgo cardiometabólico, afecta principalmente a las mujeres y a los que presentan exceso de peso. Implementar y reforzar actividades que promuevan estilos de vida saludables con participación de todos los actores sociales de la comunidad.
Enterobacterales productoras de betalactamasas en aislamientos clínicos de pacientes hospitalizados en una institución de atención secundaria.
Authors: Rodríguez-Pérez Abilio Ubaldo , Madruga-Fernández Mariela de la Caridad , Hernández-Sánchez María Cristina
Published: October 2022

Introducción: la presencia de enterobacterales productores de betalactamasas en los hospitales es cada vez más frecuente, constituyendo un problema de salud pública cada vez más grave a nivel mundial por su drogoresistencia. Objetivo: identificar enterobacterales productores de betalactamasas aislados con mayor frecuencia en muestras clínicas de pacientes hospitalizados en una institución de atención secundaria de la habana - Cuba, durante 2021. Material y Métodos: Estudio descriptivo - retrospectivo de corte transversal, que incluyeron 540 aislamientos de enterobacterales obtenidos de muestras clínicas procedentes de diferentes productos patológicos en 2021. Se determinó la resistencia bacteriana a 13 antibióticos por el método de Bauer - Kirby / difusión por discos (antibiograma interpretado). El mecanismo de resistencia por producción de BLEE y AmpC, se detectó mediante prueba de sinergia de doble disco y la prueba de aproximación de disco, respectivamente. Resultados: Escherichia coli (41%), Serratia marcescens (21%) y Klebsiella pneumoniae (18%) en orden descendente, fueron los mayores aislamientos durante el período de estudio; y la secreción traqueobronquial (35%) la muestra más significativa, a expensas de la Unidad de Cuidados Intensivos. Klebsiella pneumoniae (22%) y Escherichia coli (11%) fueron los de mayor producción de BLEE, destacándose altas cifras de resistencia para la cefotaxima, ceftazidima y ceftriaxona (100%), seguido de amoxicilina/ácido clavulánico (95%); se encontró 100 % de resistencia a la cefoxitina, cefotaxima, ceftazidima, ceftriaxona y amikacina en la única cepa bacteriana aislada productora de AmpC - Proteus mirabilis. Conclusiones: Klebsiella pneumoniae y Escherichia coli fueron los aislamientos de mayor producción de BLEE; AmpC se encontró solamente en Proteus mirabilis. Se encontraron altos porcentajes de resistencia a los antimicrobianos ensayados para todos los enterobacterales productores de betalactamasas.
Assessment of the Combination of Different Measures of Biochar and Cow Dung on Cucumber Morphological Parameters in Glo-Djigbé, Benin
Authors: Yêmadjè Alda Aude Sèna
Published: October 2022

This research aims to determine the best combination of cow dung and biochar dosages that will enable good cucumber production under the ecological conditions of the Glo-Djigbé district. This will make it possible to satisfy the growing needs of the urban population for organic crops and so reduce the use of chemical products that are harmful to the environment and the health of consumers. To carry out this research, a randomised complete Fisher block design was fixed in the experimental stage with four (04) treatments and three (03) replications; corresponding to 12 plot units, each with a surface area of 6 m² including ten patches spaced 0.8 m apart from their centre. The treatments applied per plot are: T0 (no fertilizer input), T1 (50% biochar + 50% cow dung), T2 (75% biochar + 25% cow dung), T3 (25% biochar + 75% cow dung). The collected data were analysed with Excel 2010 spreadsheet and the Statistics software. The results show that the treatments having received fertiliser were the most successful in terms of all the highlighted parameters (length, girth, number, weight of harvested fruits and yield). The best results are obtained with treatment T1 (50% Biochar + 50% cow dung). This mixture was very favourable for cucumber production and could be substituted for chemical fertilisers for organic and ecologically profitable cucumber production
GAYA BELAJAR MAHASISWA PROGRAM STUDI PENDIDIKAN TEKNIK MESIN FAKULTAS TEKNIK UNIVERSITAS NEGERI GORONTALO
Authors: Muhammad Yasser Arafat
Published: October 2022

Gaya belajar peserta didik adalah informasi awal keadaan peserta didik yang menjadi pertimbangan  dalam pemilihan metode, strategi dan model belajar yang tepat agar proses pembelajaran efektif. Deskripsi Gaya belajar masih sedikit mendapat perhatian di kalangan pendidik khusunya pada Program Studi Pendidikan Teknik Mesin Fakultas Teknik Universitas Negeri Gorontalo (FT UNG). Tujuan penelitian ini adalah mendeskripsikan gaya belajar mahasiswa Program Studi Pendidikan Teknik Mesin FT UNG. Untuk mencapai tujuan tersebut, penelitian ini menggunakan pendekatan kuantitatif jenis metode survei. Data diperoleh dari 66 sampel mahasiswa aktif Program Studi Pendidikan Teknik Mesin FT UNG dengan teknikpengambilan sampel acak sederhana.Data diolah dengan menghitung persentase jawaban kuesioner yang telah dibagikan. Berdasarkan analisis tersebut, dapat dikemukakan bahwa Mahasiswa Program Studi Pendidikan Teknik Mesin FT UNG memiliki kecendrungan gaya belajar auditori sebesar 34,85%, gaya belajar kinestetik sebesar 30,30%, dan gaya belajar visual sebesar 22,73%. Selain itu, terdapat 6,06% mahasiswa yang memiliki gaya belajar auditori-kinestetik dan 6,06% mahasiswa memiliki gaya belajar visual-auditori. Berdasarkan temuan tersebut, disarankan untuk mempertimbankan pemilihan strategi, metode, dan model belajar yang bisa mengakomodasi gaya belajar auditori, kinestetik, visual, auditori-kinestetik, dan visual-auditori sesuai dengan proporsi masing-masing gaya belajar.
PENGEMBANGAN MODUL ELEKTRONIK TUNE UP SEPEDA MOTOR PGM FI UNTUK MENINGKATKAN HASIL BELAJAR SISWA SMK
Authors: Suyitno
Published: October 2022

Selama ini Sekolah Menengah kejuruan (SMK) rata-rata sudah menggunakan buku panduan dan modul dan pembelajaran, namun masih sedikit dari guru yang membuat modul Elektronik Tune up sepeda motor.  Tujuan dari penelitian ini adalah : pengembangan modul elektronik tune up sepeda motor PGM-FI, menganalisis kelayakan modul elektronik tune up sepeda motor PGM-FI, menganalisis efektifitas modul elektronik tune up sepeda motor PGM-FI. Model pengembangan pada penelitian ini menggunakan model penelitian dan pengembangan (Research and Development). Penelitian ini menggunakan melibatkan 2 kelas siswa jurusan sepeda motor. Peningkatan nilai rata-rata pretest dan posttest sebesar 10,66 untuk kelas eksperimen, sedangkan kelas kontrol sebesar 5,67. Hasil analisis uji-t diperoleh thitung  untuk pretest sebesar 0,24 yang berarti tidak terdapat perbedaan, sedangkan untuk posttest sebesar 2,40 yang berarti adanya perbedaan yang signifikan hasil antara kelas kontrol dan kelas eksperimen. Hasil perhitungan n-gain peningkatan hasil belajar kelas eksperimen sebesar 0,39 yang termasuk dalam kategori peningkatan sedang. Hasil penilaian ahli media sebesar 89,50% dan ahli materi 84%, keduanya termasuk dalam kategori sangat layak. Analisis tanggapan siswa memperoleh hasil persentase sebesar 81,05% yang termasuk dalam kategori sangat baik. Saran untuk penelitian ini adalah modul elektronik dapat dikembangkan lagi pada kompetensi yang lain dengan model pembelajaran yang sesuai dengan kompetensinya. Modul elektronik diharapkan dapat digunakan guru dan siswa dalam proses pembelajaran.
ANALISIS PERPINDAHAN PANAS KONVEKSI ALAMIAH PIPA BERBENTUK C MENGGUNAKAN NANO FLUIDA AL2O3-AIR
Authors: David Rusli  , As Natio Lasman  , Ahmad Jibril  , Diah Hidayanti Sukarno
Published: October 2022

Salah satu cara untuk meningkatkan efektivitas pendinginan suatu sistim adalah dengan mencoba mengganti fluida kerjanya, yaitu dengan menggunakan nanofluida. Dalam penelitian ini digunakan nanofluida yang dibuat dari campuran air dengan partikel nano Al2O3 dengan konsentrasi sebesar 1%, 2%, 3% dan 4% dalam persen volume. Penelitian ini dilakukan dengan memodelkan suatu sistem dengan menggunakan software Computational Fluids Dynamic (CFD) yang terdiri dari pemanas berbentuk pipa C sebagai sumber panas di dalam tangki pendingin IRWST dengan nanofluida sebagai fluida pendingin yang dialirkan ke permukaan pemanas. Dari hasil perhitungan diperoleh distributsi temperatur untuk fluida pendingin nanofluida Al2O3 memiliki temperatur yang lebih rendah dibandingkan tanpa nanofluida. Selain itu juga diperoleh, pada kosentrasi 4% nanofluida Al2O3 memiliki nilai koefisien perpindahan panas 1.12 kali dibandingkan dengan koefisien perpindahan panas menggunakan air, hal ini menunjukkan bahwa nanofluida lebih efektif dipergunakan sebagai fluida pendingin dibandingkan air.
TINGKAT KEMATANGAN GURU DAN SISWA PENDIDIKAN VOKASIONAL DALAM MENERAPKAN KETERAMPILAN ABAD 21
Authors: Juliandarini
Published: October 2022

Until now, the maturity level of teachers and students in vocational education in applying 21st century skills in learning is still a prolonged polemic. This study aims to: (1) analyze the maturity level of teachers and students in applying 21st century skills; (2) analyze the difference in the maturity level of 21st century skills between teachers and students in implementing vocational learning. The research uses an exploratory descriptive method with a quantitative approach adopting the Hoy and Adam design. This study involved 598 samples which were divided into teacher and student subjects. Collecting data using a closed questionnaire technique with a 4-point Likert scale. Data were analyzed descriptively quantitatively to describe the percentage of maturity level and independent sample t-test to determine the difference in maturity between teachers and students. The results showed: (1) all 21st century skills consisting of problem solving, critical thinking, creativity, collaboration, communication, and digital literacy were at a low level of maturity; (2) the difference in the level of maturity experienced by teachers and students is quite significant in all competencies. Currently, 21st century skills in managing and following learning in vocational education must be strengthened again. Various training and mentoring for teachers and students should also be improved.
ANALISIS TOTAL PRODUCTIVE MAINTENANCE DENGAN METODE OEE DAN FMEA PADA MESIN EXTRUDER GW-350
Authors: Siagian Dodi , Iwan Nugraha Gusniar  , Iman Dirja
Published: October 2022

An industrial company that specializes in plastics, with the basic ingredients of PolyEthylene Terephthalate, PolyPropylene, and Hight Impact Polystyrene, the product is a plastic plate that is produced through the operation of the Extruder machine. Total Productive Maintenance (TPM) is one method of analyzing a machine and will help research the effectiveness of a machine with the help of other methods such as Overall Equipment Effectiveness (OEE) and Failure Mode and Effect Analysis (FMEA). Based on the quantitative analysis of the OEE calculation, the OEE value of the Extruder 1 GW-350 machine is obtained with an average calculation of 79.35%. Based on qualitative analysis using FMEA, the RPN failure mode score on the Extruder 1 GW-350 engine was obtained. The highest RPN value is the printer is unstable (die) at 240.
Correlação de aptidão cardiorrespiratória com Índice de Massa Corporal, perfil lipídico e parâmetros sanguíneos de militares do Exército Brasileiro: um estudo transversal
Authors: Silva Marcondes
Published: October 2022

Introdução: Uma boa aptidão cardiorrespiratória (ACR) é um componente essencial na profissão militar. Uma baixa ACR provoca diminuição no desempenho físico e na capacidade funcional, relacionando-se a perda de produtividade, internações e aumento na taxa de mortalidade.
Objetivo: Analisar as correlações de nível de ACR (volume máximo de oxigênio (VO2máx) com Índice de Massa Corporal (IMC) e parâmetros sanguíneos de militares de uma unidade militar do Exército Brasileiro.
Métodos: Estudo observacional, de corte transversal em uma amostra por conveniência, composta por 20 militares do sexo masculino. Os militares foram divididos em dois grupos conforme índices alcançados no Teste de Aptidão Física (<2.448 metros Grupo A e ≥2.448 metros grupo B). Foi apresentada a estatística descritiva (média e desvio padrão) e a análise de correlação foi para dados não paramétricos (Correlação de Spearman). O nível de confiança para todas as análises foi de 95%.
Resultados: Foi observada correlação direta de IMC com glicose, triglicerídeos (TRG), colesterol total (CT), lipoproteína de baixa densidade (LDL) e lipoproteína de densidade muito baixa. Houve correlação inversa significativa (p<0,05) de VO2máx com IMC, colesterol (VLDL e HDL) e TRG.
Conclusão: Militares com melhor ACR são apresentaram melhor perfil lipídico (menores níveis séricos de TRG, CT, LDL, VLDL e maiores níveis séricos de HDL) e menores níveis de Glicose sanguínea.
Efeito agudo do treinamento de força sobre a pressão arterial de indivíduos normotensos treinados: um estudo experimental
Authors: Ferri Christian , Moraes Gonçalves Michel , Henrique de Freitas Fabio , Gonçalves Corrêa Neto Victor , Miranda Humberto
Published: October 2022

Introdução: A hipertensão arterial sistêmica (HAS) é um fator de risco relacionado a várias comorbidades. Após uma sessão de treinamento de força (TF), a pressão arterial sistólica (PAS) e pressão arterial diastólica (PAD) podem ser reduzidas abaixo dos valores basais. Este fenômeno é conhecido como hipotensão pós-exercício (HPE). Os efeitos do TF em membros superiores (MMSS) e em membros inferiores (MMII) na HPE ainda não são completamente compreendidos.
Objetivo: Comparar o efeito agudo de uma sessão de TF multiarticular em diferentes segmentos corporais  na PA, em indivíduos normotensos treinados.
Métodos: O presente estudo experimental teve um delineamento randomizado, do tipo crossover. Foi realizado o teste de normalidade de Shapiro-Wilk e uma ANOVA two way de medidas repetidas seguida por um post hoc de Bonferroni para determinar se ocorreram diferenças significativas entre os grupos experimentais em relação a PAD e PAS em distintos momentos.
Resultados: Em relação a PAS, ambos os protocolos provocaram redução estatisticamente significativa durante a recuperação com maior magnitude de queda provocada pela sessão de MMII (p<0,05). Na PAD, não ocorreram modificações significativas após a execução de nenhum dos protocolos experimentais (p>0,05).
Conclusão: O TF multiarticular em ambos os segmentos corporais proporcionou o efeito agudo de redução da PAS, ao longo de 60 minutos após o fim da sessão de treino, com vantagem para o TF em MMII, em indivíduos normotensos treinados.
Ensemble Deep Convolution Neural Network for Sars-Cov-V2 Detection
Authors: Sarangi Subrat , Khanna Uddeshya , Kumar Rohit
Published: October 2022

The continuing Covid-19 pandemic, caused by the SARS-CoV2 virus, has attracted the eye of researchers and many studies have focussed on controlling it. Covid-19 has affected the daily life, employment, and health of human beings along with socio-economic disruption. Deep Learning (DL) has shown great potential in various medical applications in the past decade and continues to assist in effective medical image analysis. Therefore, it is effectively being utilized to explore its potential in controlling the pandemic. Chest X-Ray (CXR) images were used in studies pertaining to DL for medical image analysis. With the burgeoning of Covid-19 cases by day, it becomes imperative to effectively screen patients whose CXR images show a tendency of Covid-19 infection. Several innovative Convolutional Neural Network (CNN) models have been proposed so far for classifying medical CXR images. Moreover, some studies used a transfer learning (TL) approach on state-of-art CNN models for the classification task. In this paper, we do a comparative study of these CNN models and TL approaches on state-of-art CNN models and have proposed an ensemble Deep Convolution Neural Network model (DCNN)
Implementation of AI based Safety and Security System Integration for Smart City
Authors: Doohan Nitika Vats , Kadam Sandeep , Phursule Rajesh , Wadne Vinod S. , Junnarkar Aparna
Published: October 2022

Our Indian government has set a goal of creating 100 smart cities that will use smart technology such as smart grids, smart phones, and various monitoring devices to generate large amount of data. Traditionally, data centres have been in charge of these files. One of the most pressing issues in data centres is resource management. One efficient strategy to address this issue is to use the best method for handling data, and when we're talking about Smart Cities, which will create a big quantity of data, it's becoming increasingly important to manage this massive amount of data.

It is also necessary to provide the better living standard for every citizen in the smart cities by providing good safety and security to them as well. As we know that every citizen is not smart enough to protect himself against the physical as well as cyber-crimes. In this paper, we have designed an advanced Artificial Intelligence (AI) based safety and security system for the human beings and their personal data in a smart city. The system architecture is designed with AI module with machine learning algorithms, IoT technology and sensors, smart drones, intelligent video surveillances, data analytics and cyber security modules. This system can efficiently protect the citizens and their personal data against the criminals with high speed and accuracy.
An Analysis of the Financial Asset Ratio Influenced by the Characteristics of Household
Authors:   Korea Real Estate Society, Kim Hyoung Jun , Park Mun Su
Published: October 2022

The purpose of this study is to present the asset management strategies of households and the government by analyzing the impact of household characteristics on financial assets as well as real estate assets. Specifically, this study attempts to verify the relationship with the financial asset ratio of households through household characteristics such as life cycle, occupancy type, real estate asset ratio, and total debt. In order to fully understand the reason why the financial asset ratio of households is relatively low, the relationship between household characteristics and the financial asset ratio was verified. The analysis results are as follows. Firstly, the characteristics of the older generation (of the life cycle) have a negative influence on the financial asset ratio. Secondly, housing instability in the form of occupation (in the case of monthly rent, not self-owned), negatively affects the financial asset ratio. Thirdly, it was found that the higher the ratio of real estate assets, the more negative influence on the ratio of financial assets. Finally, total liabilities have a negative effect on the ratio of financial asset ratio. In conclusion, this study argues that the characteristics of household assets biased toward real estate assets have a problematic issue, which is that it is difficult to generate steady cash flow in old age after retirement, and that active policy changes are required to increase the proportion of financial assets in households.
A Study on the Determinants of the Realization Rate of Medium and Large Office Sales Prices in Seoul
Authors:   Korea Real Estate Society, Jung Kwang Hwa , Lee Myeng Hun
Published: October 2022

This study used the Hedonic model to help introduce and establish a system to realize the official price of non-residential real estate medium and large office buildings, and based on previous studies, it selected transaction characteristics, location characteristics, and building characteristics as dependent variables. As a result of hypothesis verification, all three hypotheses related to transaction characteristics, three hypotheses related to location characteristics, and four related to building characteristics were adopted. Among the transaction characteristics, the factors adopted as determinants of the office building realization rate were sales price, 3 years of treasury bonds, 1 transaction number, and 2 transactions. Among the location characteristics, it was identified as more than 500m of land area, GBD, YBD, CBD, Others, subway station, and 20m of commercial area, roadside, and access road. In the case of building characteristics, a total of 19 factors were adopted as the floor area ratio, total floor area, total number of floors, rectangular, irregular, and less than 30 years of construction year. Since the variables adopted in this way are the main factors related to the determining factor of the official price realization rate of medium and large office buildings, it is expected that the third stage of non-residential real estate public price unification can be accelerated.
STUDY OF NEGATIVE REFRACTIVE INDEX IN Rb FOUR-LEVEL N-TYPE ATOMIC GAS MEDIUM
Authors: Nguyen Huy Bang , Le Nguyen Mai Anh , Le Thi Minh Phuong , Ho Hai Quang , Le Van Doai
Published: October 2022

In this work, we study the generation of a negative refractive index based on electromagnetically induced transparency (EIT) in a Rb four-level N-type atomic gas medium. We derive analytic expressions for the relative permittivity and relative permeability of the medium according to the parameters of the probe, pump, and signal laser fields. We then investigate the variation of the real parts of the relative permittivity and relative permeability with respect to the intensity and frequency of the pump and signal laser fields. In the presence of the pump laser beam, the medium becomes transparent to the probe laser beam even in the resonant region. At the same time, the real parts of the relative permittivity and relative permeability are simultaneously negative (i.e., the medium exhibits a negative refractive index) in the EIT spectral domain. In the presence of the signal laser beam, the EIT effect occurs over two different frequency domains of the probe beam, so a negative refractive index is also generated in these two frequency domains. The investigation of the real parts of the relative permittivity and relative permeability with intensity and frequency of the pump and signal laser fields allowed us to find the laser parameters for the appearance of the negative refractive index, which can be useful for experimental observations.
Dijital Oyunlar ve Şiddet
Authors: PENEZOĞLU YILDIRIM Döndü Nilay , ULUKOL Betül
Published: October 2022

Oyun, çocuğun farklı gelişim alanlarına katkı sağlayan önemli bir etkinlik ve çocuklar için bir anlaşma yoludur. Çocuğun fiziksel ve zihinsel gelişimine katkı sağlarken nesnelerle ilişki kurmasına da yardımcı olur. Aynı zamanda çocuğun özgürleşmesi, bireyselleşmesi ve toplumsallaşmasında önemli bir etkiye sahiptir. Oyunlar özellikle çocukların toplum kurallarını öğrenmesini, hayata hazırlanmasını ve yeni nesillere kültürün aktarılmasını da sağlamaktadır. Zaman içerisinde, özellikle tarım toplumundan sanayileşmeye geçiş ile birlikte kalabalık ve ev dışında olan oyun ortamları yerini daha az sayıda çocuğun bulunduğu, sınırlı oyun alanlarına bırakmıştır. Bu değişimi sonraki yıllarda bilgi toplumuna geçiş izlemiştir. Gerek sanayileşme ve beraberinde gelen şehirleşme gerekse teknoloji alanında yaşanan gelişmeler gerçek dünyada oyun alanlarının daralması ile sonuçlanmıştır. Gerçek dünyanın sunduğu oyun alanları bu kadar daralırken diğer tarafta sanal dünyanın sunduğu oyun alanları ise bir hayli genişlemiştir.
Expression and signaling pathways of Nerve Growth Factor (NGF) and pro-NGF in breast cancer: a systematic review
Authors:   Regional Neurogenetic Centre - ASPCZ, Lamezia Terme (CZ), Italy, Bruno Francesco , Arcuri Domenico , Vozzo Francesca , Malvaso Antonio , Montensanto Alberto , Maletta Raffaele
Published: October 2022

Review question / Objective: This study aims to systematically review and comprehensively summarize the current experimental evidence about the involvement of Nerve Growth Factor (NGF) and pro-NGF signaling pathways in breast cancer. Therefore, the questions are as follows: (1) What is the expression level of NGF, pro-NGF and their receptors in breast cancer? (2) What is the role played by NGF, pro-NGF and their receptors in the pathophysiological mechanisms (i.e., proliferation, apoptosis, angiogenesis, invasion, metastasis) of breast cancer? (3) What is the diagnostic, prognostic and therapeutic potential of NGF, pro-NGF and their receptors in breast cancer? Condition being studied: Breast cancer is a neoplasm of epithelial origin that generally develops in the parts of the breast tissue made up of the glands involved in milk production or in the ducts that connect the glands to the nipple. In women it represents the most frequent cancer as well as the leading cause of cancer death. The incidence of breast cancer is estimated to increase over the years and to reach 3.2 million in 2050, thus representing a health emergency both from a medical and a psychological point of view. Therefore, prevention and early diagnosis of breast cancer appears to be of primary urgency as well as the development of new treatments able to improve its prognosis.
A systematic review of factors influencing immigrant parents' service choices for children with ASD
Authors:   University of California, Santa Barbara, Zhang Hui
Published: October 2022

Review question / Objective: What main concerns/factors influenced immigrant parents when deciding on an intervention, service, or agency? Condition being studied: The systematic review aims at understanding immigrant parents' service choices for their children with the diagnosis of ASD(autism spectrum disorder), which is a complex neurobehavioral disorder characterized by impairment in reciprocal social interaction, impairment in communication, and the presence of repetitive and stereotypic patterns of behaviors, interests, and activities developmental disability.
Quality of Evidence Supporting the Effects of Xinmailong injection in Heart Failure: An Overview of Systematic Reviews and Meta-Analyses
Authors:   Shandong University of Traditional Chinese Medicine, Jinan, People’s Republic of China, Wu Xiaoqi , Zhao Jisen , Fan Maoxia , Guo Dongo
Published: October 2022

Review question / Objective: 2.1.1 type of research SRs/MAs of RCT (randomized controlled trial) of Xinmailong injection for the treatment of heart failure. 2.1.2 Subject investigated All included patients met internationally recognized diagnostic criteria for heart failure.There are no limitations on age, gender, ethnicity, time of onset, source of cases and language of publication. 2.1.3 Type of Intervention The control group was treated with conventional basic Western medicine recommended by the guidelines related to heart failure[1, 11], including antiplatelet drugs, anticoagulants, vasodilators, beta-blockers,ACEI (angiotensin-converting enzyme inhibitors), lipid-lowering drugs, and diuretic agents. and other drug treatment. The intervention group was given Xinmailong injection on the basis of the control group.
Efectos de la cadena de valor del café en el desarrollo socioeconómico de los pequeños cafetaleros de Corquín, departamento de Copán-Honduras.
Authors: Barreto Elizabeth
Published: October 2022

Esta investigación tuvo como objetivo determinar los efectos de la cadena de valor del café en el desarrollo socioeconómico de los pequeños cafetaleros de Corquín, departamento de Copán-Honduras, para proponer estrategias participativas que contribuyan a fortalecer la productividad y posicionar el rubro. Mediante metodología mixta descriptiva con diseño no-experimental transversal e investigación acción, se obtuvo la información de 140 pequeños cafetaleros y 14 organizaciones. Entre los resultados destaca la importancia de las organizaciones gubernamentales y no gubernamentales en el proceso productivo del café, se constató que la mayoría de los productores tienen cuidados rigurosos de control de malezas, plagas y enfermedades, tratan de emplear como tecnología la fertilización de los cultivos, han logrado mejorar sus condiciones de vida por medio de la comercialización, las carreteras se encuentran en buen estado lo que facilita la movilización del café extraído de las fincas hacia las viviendas y posteriormente hacia el exterior de las fincas. Como conclusión es importante seguir impulsando el desarrollo de los cafetaleros por medio de la integración de mejores procesos de capacitación, apoyo en cuanto a la dotación de mayor cantidad de insumos y la oportunidad de crecimiento a través de la comercialización de los productos,
Conclusion and performance of commercial contracts with the use of information technologies
Authors: Filippova S. Y.
Published: October 2022

The article attempts to evaluate the possibilities of using blockchain and smart contract technologies, as well as big data and artificial intelligence technologies in traditional commercial contracts. In addition, the author illustrates the legal risks of using information technologies and the limits of their implementation in the field of contract law. The goal chosen by the author predetermined the use of the formal legal method in the analysis of the current legal norms. At the same time, it is impossible to imagine the search for answers to the questions without referring to the comparative legal method: in the article, the author refers to the views of English and American scholars when considering the problems of using artificial intelligence technology in commercial contracts.

As a result of the research, the author comes to the conclusion that firstly smart contracts designed for automatic transactions on the Internet do not allow moving real goods in the real world, therefore the scope of their use is only limited to the conclusion, but not to the execution of contracts of sale. Secondly, a smart contract can completely supplant traditional contracts and obligations in mediation contracts aimed at performing only legal actions. Thirdly, there is a problem of ensuring the right to privacy when using big data, therefore, the commercial use of the collected data, though does improve sales, violates basic human rights. And finally, the mastered capabilities for automating the processes of selecting counterparties, determining and changing storage conditions, tracking the balance of goods in the warehouse, etc., allow author to discuss the potentially great possibilities of using AI in commerce.
THE ROLE OF ISLAMIC GOVERNMENT IN BUMI MELAYU
Authors: Hanif Muhammad , Dwi Dian
Published: October 2022

ABSTRAK

Melayu berasal dari kata Malaya dvipa dari kitab Hindu Purana yang berarti tanah yang dikelilingi air yang merujuk pada sebuah Kerajaan Melayu Kuno di Jambi pada abad ke-7. Malayu atau Melayu hingga kini terkadang diidentikkan dengan Riau dan sekitarnya. Masyarakat melayu pada umumya identik dengan Islam yang menjadi pondasi dari sumber adat istiadatnya. Oleh karena itu, adat istiadat orang Melayu Riau bersendikan syarak dan syarak bersendikan Kitabullah. Budaya melayu di Provinsi Riau tidak hanya meninggalkan sebuah momentum historis kultural saja, namun juga meninggalkan beragam perspektif antara lain seperti pemerintahan,pendidikan dan kebudayaan. Sebelum Indonesia merdeka dan Riau bergabung kedalamnya sebagai bagian dari wilayah teritorial, model pemerintahannya adalah monarki (kerajaan). Sistem pemerintahan kerajaan di Riau mengenal kontrak politik antara raja dengan rakyat. Berakhirnya pola sistem pemerintahan monarki ini ditandai dengan bergabungnya Kerajaan Melayu Riau kedalam bagian Negara Kesatuan Republik Indonesia pasca kemerdekaan 17 Agustus 1945. Tulisan ini secara historis akan melihat bagaimana Islam sebagai jiwa kebudayaan Melayu terbentuk, berproses, dan bernegoisasi yang akhirnya membentuk suatu kebudayaan yang hadir di sejarah Nusantara ini. Bagaimana peran politik Islam sangat kental dalam mengatur sendi-sendi kehidupan masyarakat melayu. Pada bagian pertama melihat bagaimana sejarah Kemelayuan di Nusantara. Bagian kedua, secara kritis melihat sistem pemerintahan kerajaan melayu dan fase perubahan dari Hindu ke Islam
THE ROLE OF KARAWANG PEDULI FOUNDATION INSTITUTION IN HUMANITARIAN PROGRAMS AGAINST THE PEOPLE OF KAMPUNG CIRENDEU DESA CIPTASARI PANGKALAN KARAWANG DISTRICT
Authors: Jumroni  , Haq Iqbal fathul
Published: October 2022

Penelitian ini bertujuan untuk mengetahui Peran lembaga Karawang Peduli Foundation dalam program kemanusiaan terhadap masyarakat pelosok Kampung Cirendeu Desa Ciptasari Kecamatan Pangkalan Kabupaten Karawang. Metode Penelitian: Metode yang dipakai dalam penelitian kali ini yaitu menggunakan metode kualitatif dengan menggunakan teknik analisis data model interaksi Miles & Huberman dengan teori peran lembaga swadaya masyarakat yang dikemukakan oleh Zubaedi. Hasil Penelitian : Peran Karawang Peduli Foundation dalam program kemanusiaan yaitu sebagai fasilitator, pendidik atau educator, perantara atau mediator, dan teknikal. Kesimpulan : Dalam hasil penelitian ini didapatkan bahwa peran lembaga Karawang Peduli Foundation yaitu 1. Sebagai fasilitator yang memberikan stimulasi dan dukungan kepada masyarakat yang membutuhkan uluran tangan dalam berbagai kegiatan kemanusiaan. 2. Sebagai pendidik yang memberikan pendidikan baik di bidang sosial maupun keagamaan. 3. Sebagai perantara dalam menghubungkan aset kesejahteraan sosial. 4. Sebagai teknikal dalam pengelolaan program peningkatan kesejahteraan sosial. Peran tersebut terdapat pada program kemanusiaan yang dilakukan oleh lembaga Karawang Peduli Foundation terhadap masyarakat pelosok Kampung Cirendeu.
THE RESPONSE OF FORMER TERRORISM PRISONERS TO THE ASSISTANCE OF THE INSAN CITA FOUNDATION THROUGH THE TECHNICAL GUIDANCE PROGRAM IN MAKASSAR CITY
Authors: Samsono Agus , MUTIAH SHOLEHAH
Published: October 2022

Muslims have a misunderstanding of the ideology of terrorism with the doctrine of jihad. The Islamic community does not have the power to understand their own religion, because there are people who give knowledge to themselves who are wrong about Islam, so that the community gets a misunderstanding about jihad. Terrorism is an event that worries all nations in the world, including Indonesia. Cases of terrorism have led to the emergence of government programs in an effort to deradicalize terrorists so that they no longer commit the same crimes. One of the efforts of the government and social welfare institutions is through the technical guidance program. The purpose of this study was to determine the response of former terrorist convicts to the assistance of the Insan Cita Foundation through the Bimbtek Program in Makassar City. The research method used is qualitative method. The results of the study indicate that the response of former terrorism convicts to the Insan Cita Foundation assistance through a technical guidance program in Makassar City, from a cognitive perspective, ex-terrorism convicts are able to recognize the program being followed. Then from the affective aspect, it can be seen with the feelings of former terrorism convicts who are quite satisfied with the technical guidance program. And from a conative perspective, ex-terrorism convicts have been able to determine their attitude about what to do after this technical guidance program is implemented. As for the mentoring stage, this research is more inclined to the facilitation stage because this program provides guidance and capital facilities for ex-terrorism convicts as program participants.
THE IMPACT OF TECHNOLOGICAL DEVELOPMENT ON TRANSPORT ENTERPRISES’ MARKETING STRATEGY (LITHUANIAN EXAMPLE)
Authors: Išoraitė Margarita , Jarašūnienė Aldona , Vaičiūtė Kristina
Published: October 2022

The article analyses the influence of technological development of transport enterprises on marketing strategies in the light of academic literature which highlights the importance of technological development tools. Technological development of enterprises in the transport sector is necessary in order to adapt to technological, economic, and market changes. The article presents major technological developments which are considered significant according experts. The most important technological development tools which influence marketing strategies of transport enterprises are presented. In order to examine the tools of transport development, a qualitative analysis was performed, and the method of statistical analysis was applied. The research results can be applied in planning marketing strategies of transport enterprises.
The K2-3 System Revisited: Testing Photoevaporation and Core-powered Mass Loss with Three Small Planets Spanning the Radius Valley
Authors: Diamond-Lowe Hannah , Kreidberg Laura , Harman C. E. , Kempton Eliza M.-R. , Rogers Leslie A. , Joyce Simon R. G. , Eastman Jason D. , King George W. , Kopparapu Ravi , Youngblood Allison , Kosiarek Molly R. , Livingston John H. , Hardegree-Ullman Kevin K. , Crossfield Ian J. M.
Published: October 2022

Multiplanet systems orbiting M dwarfs provide valuable tests of theories of small-planet formation and evolution. K2-3 is an early M dwarf hosting three small exoplanets (1.5–2.0 R
⊕) at distances of 0.07–0.20 au. We measure the high-energy spectrum of K2-3 with HST/COS and XMM-Newton and use empirically driven estimates of Lyα and extreme-ultraviolet flux. We use EXOFASTv2 to jointly fit radial velocity, transit, and spectral energy distribution data. This constrains the K2-3 planet radii to 4% uncertainty and the masses of K2-3b and c to 13% and 30%, respectively; K2-3d is not detected in radial velocity measurements. K2-3b and c are consistent with rocky cores surrounded by solar composition envelopes (mass fractions of

0.36

−
0.11

+
0.14

%

and

0.07

−
0.05

+
0.09

%

), H2O envelopes (

55

−
12

+
14

%

and

16

−
10

+
17

%

), or a mixture of both. However, based on the high-energy output and estimated age of K2-3, it is unlikely that K2-3b and c retain solar composition atmospheres. We pass the planet parameters and high-energy stellar spectrum to atmospheric models. Dialing the high-energy spectrum up and down by a factor of 10 produces significant changes in trace molecule abundances, but not at a level detectable with transmission spectroscopy. Though the K2-3 planets span the small-planet radius valley, the observed system architecture cannot be readily explained by photoevaporation or core-powered mass loss. We instead propose that (1) the K2-3 planets are all volatile-rich, with K2-3d having a lower density than typical of super-Earths, and/or (2) the K2-3 planet architecture results from stochastic processes such as planet formation, planet migration, and impact erosion.
Gravitational Wave Sources in Our Galactic Backyard: Predictions for BHBH, BHNS, and NSNS Binaries Detectable with LISA
Authors: Wagg T. , Broekgaarden F. S. , de Mink S. E. , Frankel N. , van Son L. A. C. , Justham S.
Published: October 2022

Future searches for gravitational waves from space will be sensitive to double compact objects in our Milky Way. We present new simulations of the populations of double black holes (BHBHs), BH neutron stars (BHNSs), and double neutron stars (NSNSs) that will be detectable by the planned space-based gravitational-wave detector called Laser Interferometer Space Antenna (LISA). For our estimates, we use an empirically informed model of the metallicity-dependent star formation history of the Milky Way. We populate it using an extensive suite of binary population-synthesis predictions for varying assumptions relating to mass transfer, common-envelope, supernova kicks, remnant masses, and wind mass-loss physics. For a 4(10) yr LISA mission, we predict between 30–370(50–550) detections over these variations, out of which 6–154 (9–238) are BHBHs, 2–198 (3–289) are BHNSs, and 3–35 (4–57) are NSNSs. We expect that about 50% (60%) can be distinguished from double white dwarf sources based on their mass or eccentricity and localization. Specifically, for about 10% (15%), we expect to be able to determine chirp masses better than 10%. For 13% (13%), we expect sky-localizations better than 1°. We discuss how the variations in the physics assumptions alter the distribution of properties of the detectable systems, even when the detection rates are unchanged. We further discuss the possibility of multimessenger observations of pulsar populations with the Square Kilometre Array and assess the benefits of extending the LISA mission.
Topography of the Young Galactic Disk: Spatial and Kinematic Patterns of Clustered Star Formation in the Solar Neighborhood
Authors: Alfaro Emilio J. , Jiménez Manuel , Sánchez-Gil M. Carmen , Sánchez Néstor , González Marta , Apellániz Jesús Maíz
Published: October 2022

The accuracy in determining the spatial-kinematical parameters of open clusters makes them ideal tracers of the Galactic structure. Young open clusters (YOCs) are the main representatives of the clustered star formation mode, which identifies how most of the stars in the Galaxy form. We apply the Kriging technique to a sample of Gaia YOCs within a 3.5 kpc radius around the Sun and log(age) ≤ 7.5, as the age in years, to obtain Z(X, Y) and V

Z
(X, Y) maps. Previous work by Alfaro et al. has shown that Kriging can provide reliable results even with small data samples (N ∼ 100). We approach the 3D spatial and vertical velocity field structure of the Galactic disk defined by YOCs and analyze the hierarchy of the stellar cluster formation, which shows a rich hierarchical structure, displaying complexes embedded within each other. We discuss the fundamental characteristics of the methodology used to perform the mapping and point out the main results obtained in phenomenological terms. Both the 3D spatial distribution and the vertical velocity field reveal a complex disk structure with a high degree of substructures. Their analysis provides clues about the main physical mechanisms that shape the phase space of the clustered star formation in this Galactic area. Warp, corrugations, and high local deviations in Z and V

Z
appear to be intimately connected, in a single but intricate scenario.
H i HOD. I. The Halo Occupation Distribution of H i Galaxies
Authors: Qin Fei , Howlett Cullan , Stevens Adam R. H. , Parkinson David
Published: October 2022

The next generation of galaxy surveys will provide more precise measurements of galaxy clustering than have previously been possible. The 21 cm radio signals that are emitted from neutral atomic hydrogen (H i) gas will be detected by large-area radio surveys such as the Widefield Australian Square Kilometre Array (SKA) Pathfinder L-band Legacy All-sky Blind Survey and SKA, and deliver galaxy positions and velocities that can be used to measure galaxy clustering statistics. However, to harness this information to improve our cosmological understanding and learn about the physics of dark matter and dark energy, we need to accurately model the manner in which galaxies detected in H i trace the underlying matter distribution of the universe. For this purpose, we develop a new H i-based halo occupation distribution (HOD) model, which makes predictions for the number of galaxies present in dark matter halos conditional on their H i mass. The parameterized HOD model is fit and validated using the Dark Sage semi-analytic model, where we show that the HOD parameters can be modeled by simple linear and quadratic functions of the H i mass. However, we also find that the clustering predicted by the HOD depends sensitively on the radial distributions of the H i galaxies within their host dark matter halos, which does not follow the Navarro–Frenk–White profile in the Dark Sage simulation. As such, this work enables—for the first time—a simple prescription for placing galaxies of different H i masses within dark matter halos in a way that is able to reproduce the H i mass-dependent galaxy clustering and H i mass function simultaneously and without requiring knowledge of the optical properties of the galaxies. Further efforts are required to demonstrate that this model can be used to produce large ensembles of mock galaxy catalogs for upcoming surveys.
Generation of Solar Coronal White-light Images from SDO/AIA EUV Images by Deep Learning
Authors: Lawrance Bendict , Lee Harim , Park Eunsu , Cho Il-Hyun , Moon Yong-Jae , Lee Jin-Yi , A Shanmugaraju , Rahman Sumiaya
Published: October 2022

Low coronal white-light observations are very important to understand low coronal features of the Sun, but they are rarely made. We generate Mauna Loa Solar Observatory (MLSO) K-coronagraph like white-light images from the Solar Dynamics Observatory/Atmospheric Imaging Assembly (SDO/AIA) EUV images using a deep learning model based on conditional generative adversarial networks. In this study, we used pairs of SDO/AIA EUV (171, 193, and 211 Å) images and their corresponding MLSO K-coronagraph images between 1.11 and 1.25 solar radii from 2014 to 2019 (January to September) to train the model. For this we made seven (three using single channels and four using multiple channels) deep learning models for image translation. We evaluate the models by comparing the pairs of target white-light images and those of corresponding artificial intelligence (AI)–generated ones in October and November. Our results from the study are summarized as follows. First, the multiple channel AIA 193 and 211 Å model is the best among the seven models in view of the correlation coefficient (CC = 0.938). Second, the major low coronal features like helmet streamers, pseudostreamers, and polar coronal holes are well identified in the AI-generated ones by this model. The positions and sizes of the polar coronal holes of the AI-generated images are very consistent with those of the target ones. Third, from AI-generated images we successfully identified a few interesting solar eruptions such as major coronal mass ejections and jets. We hope that our model provides us with complementary data to study the low coronal features in white light, especially for nonobservable cases (during nighttime, poor atmospheric conditions, and instrumental maintenance).