bluuebunny/crossref_metadata_2025 huggingface dataset:
EVALUATION OF TRACK ETCH MEMBRANE AS A SURROGATE FOR EX-VIVO DRUG PERMEATION STUDIES
Authors: Garg Ravish , Girotra Priti , Singh Shailendra Kumar , Kumar Dinesh , Chakarvarti S. K.
Published: January 2025

The track etch membranes has attracted the attention of researchers, as a kind of novel material, for their various applications such as precise separation of biological cells, detection of biomolecules and controlled drug release, especially for pharmaceutical and biomedical applications. In the present study, the efficacy of track etch membrane over goat skin for the Ex-vivo permeation of silver sulfadiazine gel has been investigated with the objective to evaluate track etch membrane as a surrogate for biological membrane owing to ethical issues and scarce availability of biological skins. The percent cumulative drug release from silver sulfadiazine gel using track etch membrane and goat skin were obtained as 18.18 % and 20.99 % respectively. The results obtained from track etch membrane and goat skin was similar with only a slight difference in percent drug diffusion which might be because of the lipids present in animal skin. Track etch membrane has the potential to mimic the animal skin for such ex-vivo drug diffusion studies with certain additional advantages such as sufficient mechanical strength and ruggedness. It can be efficiently reused and also surpasses the ethical issues involved with the use of biological membrane.
MICROWAVE-ASSISTED SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF SOME PYRAZOLE DERIVATIVES
Authors: Swarnkar Deepak , Ameta Rakshit , Vyas Ritu
Published: January 2025

Reaction of 3-[4-(dimethylamino)phenyl]-(1-methyl/phenyl)prop-2-en-1-one (Chalcones) was carried out with hydrazine hydrate, phenyl hydrazine, isoniazide, nicotinic hydrazide and thiosemicarbezide (corresponding hydrazides) in ethanol containing a few drops of glacial acetic acid under microwave irradiation giving N, N-dimethylaniline containing pyrazole derivatives. The structures of the synthesized compounds were assigned on the basis of elemental analysis, IR and 1H NMR. All the synthesized compounds have been screened for their antibacterial and antifungal activities.
DETERMINATION OF DULOXETINE AND ITS MAJOR METABOLITES IN RABBIT PLASMA BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY
Authors: Laha T. K. , Sen S. , Mishra G.
Published: January 2025

A rapid and sensitive high performance liquid chromatographic method is described for simultaneous determination of duloxetine and its major metabolites, such as 4- hydroxy duloxetine (M7), Glucuronide conjugate of 5-hydroxy-6-methoxy duloxetine (M6) and Glucuronide conjugate of dihydrodiol duloxetine (M12) in rabbit plasma. HPLC analysis was carried out on a µ-Bondapak C18 column (250 mm × 4.6 mm, 5µm particle size) using methanol: phosphate buffer (pH 7.9, 50 mM) (7:3 v/v) as the mobile phase at a flow rate of 1.5 ml/min. Detection was carried out at 224 nm with an UV detector. The above metabolites present in the rabbit plasma were characterized by retro-synthesis followed by NMR and MS study for structure confirmation and finally injected separately into the HPLC system. All the three retention time matches with the metabolites present in the plasma sample.
FORMULATION AND OPTIMIZATION OF RAFT FORMING CHEWABLE TABLET CONTAINING LAFUTIDINE
Authors: Patel Dasharath M. , Patel Dimpal G. , Patel Chhagan N.
Published: January 2025

Lafutidine is a new histamine H2- receptor antagonist having biological half-life of 1.92 h. Due to its selective absorption from upper part of gastrointestinal tract the gastroretentive drug delivery is desired in order to enhance its bioavailability. The aim of research was to formulate chewable tablets of lafutidine along with raft forming agent, antacid and gas generating agent. Tablets were prepared by wet granulation method and evaluated for raft strength, acid neutralization capacity, weight variation, % drug content, and in vitro drug release. Various raft-forming agents were used in preliminary screening. A 32 full factorial design was used for optimization in present study. Amount of calcium carbonate and ratio of sodium alginate to pectin were used as independent variables while raft strength and acid neutralizations capacity were used as dependent variables. Batch F8 was selected as optimized formulation based on maximum raft strength and good acid neutralization capacity. Drug-excipients compatibility study showed no interaction between drug and excipients. Stability study of the optimized formulation showed that the tablets were stable at accelerated environmental conditions for 1 month. It was concluded that raft forming chewable tablets prepared using an optimum amount of sodium alginate, pectin and calcium carbonate could be an efficient dosage form in the treatment of gastro oesophageal reflux disease.
PHARMACOLOGICAL EVALUATION AND DETECTION OF ANACARDIC ACID IN CALLUS CULTURE AND VARIOUS PLANT PARTS OF ANACARDIUM OCCIDENTALE L.
Authors: L. Sija. S. , P. Potty. V. , S. Santhoshlal. P.
Published: January 2025

Anacardium occidentale L. is much known for its commercially valuable kernals and also bioactive compounds like polyphenols which serve as natural antioxidant having an ability to quench cytotoxic free radicals that may prevent many diseases. The present study was carried out to evaluate the presence of anacardic acid, total phenolic compound, antioxidant activity and antibacterial activity in methanolic extract of callus and various plant parts such as flower, young leaves, shoot and cotyledon. Total phenolic contents were measured by the Folin-Ciocalteau method using gallic acid as standard compound. The maximum phenolic content was found in the methanol extract of flower (260.8 ± 5.543 mg/g) whereas the methanol extract of cotyledon (16.2 ± 3.284 mg/g) showed the lowest total phenolic content. The action of 1, 1-diphenyl-2-picrylhydrazyl (DPPH) on radical scavenging effect of the extracts was determined spectrophotometrically using ascorbic acid as standard compound. All extracts exhibited a DPPH radical scavenging activity and among the extracts, A. occidentale flower demonstrated greater antioxidant potential with a low IC50 (206.312 ± 0.38µg/ml) in comparison with those of the other extracts. Total phenolic contents showed positive correlations with the DPPH radical scavenging activity (r = 0.979; p<0.01) and negative correlations with IC50 (r = -0.984; p<0.01). The antibacterial capabilities of various extracts were also investigated against two common human pathogens of clinical importance, Escherichia coli and Staphylococcus aureus. Presence of anacardic acid in various extracts was also estimated by using HPTLC method. Pre-coated aluminum silica gel plate 60F254 was used as stationary phase and chloroform: ethyl acetate (9:1) was used as mobile phase.
PRESCRIPTION PATTERN AND THERAPEUTIC RESPONSE OF VARIOUS ANTI HYPERTENSIVE DRUGS FOR THE HYPERTENSIVE PATIENTS AT PRIVATE HOSPITALS IN TAMILNADU, INDIA
Authors: Karthikeyan G. , Ranganayakulu D.
Published: January 2025

The present study was conducted in order to establish the therapeutic responses and prescription pattern of various antihypertensive agents in patients with mild, moderate and severe hypertension. Prospective and comparative study was carried out on 500 patients attending the cardiology out patients department at private hospitals in Tamilnadu, India. Patients of either sex aged between 18-60 years suffering from hypertension and to evaluate the characterization, drug therapy (mono or combination) of five major categories of antihypertensive drugs in patients with hypertension. Out of 500 patients, males (49.29 ± 6.5) and females (50.63 ± 6.5) participated in the study. This study revealed that most of the patients were on mono therapy (43%, Male and 28% Female) and in combination therapy (17% male and 12% Female). In mono therapy, five classes of drugs were used. These were diuretics (33%), beta-blockers (20%), calcium channel blockers (19%), ACE inhibitors (17%) and angiotensin II receptor blocker (11%). Among mono therapy of drugs, diuretics were prescribed most whereas angiotensin II receptor blocker were least used, In combination therapy, angiotensin II receptor blocker and thiazide diuretic was given to the majority of the patients (42%), beta blocker and thiazide diuretic were (32%), calcium channel blocker and beta blocker were (15%) and ACE Inhibitor and calcium channel blocker were (10%). The present study represents the current prescribing pattern of anti-hypertensive drugs and it highlights certain shortcomings in the existing prescribing practice. There is a considerable scope for improvement on patient’s interaction with pharmacist and doctors and needs to improve pharmaceutical care on disease and drug knowledge for the effective blood pressure control.
PRODUCTION AND OPTIMIZATION OF Α-AMYLASE FROM ASPERGILLUS FLAVUS UNDER SOLID STATE FERMENTATION
Authors: Manivannan S. , Madhavi P. , Bhuvaneswari S.
Published: January 2025

Alpha amylase is one of the important and well known industrial enzymes that cause the breakdown of starch or glycogen. Use of microorganism for the production of amylase is economical as microbes are easy to manipulate to obtain enzymes of desired characteristics. However fungus is preferred over bacteria for enzymes production because of its filamentous nature. Agricultural wastes byproducts have great potential for the production of enzymes. Two indigenous carbon sources namely wheat bran and rice bran were used as substrate for amylase synthesis by Aspergillus flavus through solid state fermentation. Wheat bran gave the highest (670 ± 36μmol./min/mL) and Rice bran (428 ± 24μmol./min/mL) gave the lowest enzyme activity was obtained. Optimum inoculum size of 10% (660 ± 36μmol./min/mL), incubation period 120 hours (670 ± 28 μmol./min/mL), pH 6 (680 ± 42μmol./min/mL), temperature at 30°C (660 ± 46μmol./min/mL) gave highest yield of enzyme production. The highest yield of amylase production was obtained by the addition of MgSO4 0.2% and CaCl2 0.02% respectively. The results obtained in the present study suggest that the Aspergillus flavus may act as a potent strain for industrial production of α-amylase.
IN VITRO INHIBITION OF CANDIDA SPECIES BY AQUEOUS GARLIC EXTRACT IN GEL AND LOTION: PROBLEM OF STABILITY
Authors: Shaqra Q. M. Abu , Shaqra A. Q. Abu
Published: January 2025

The inhibitory effect of aqueous garlic extract (AGE) against clinically significant microorganisms including Candida species is documented. The activity and stability of this extract in topical pharmaceutical formulations has received little attention. This communication reports on the stability and anticandidal activity of AGE in gel and lotion formulations. Gel and lotions containing 50, 100 and 200 mg garlic/ml were prepared and their physical as well as biological stability was established at 40ºC. The anticandidal effect of all preparations was determined using the well diffusion method and Muller Hinton agar. Results indicated that both of the prepared formulations were physically stable but the freshly prepared lotion exhibited no anticandidal effect. Gels were effective inhibitors but this activity was lost with storage at 40ºC in less than 9 days. It is concluded that lotion was not at all a suitable delivery system for AGE as it lost its activity during preparation. Whereas, freshly prepared gels were good inhibitors but this property was diminished upon storage. Comprehensive studies are needed to stabilize the AGE gel formulation over the expected shelf life.
DENDRIMERS AS A POTENTIAL DRUG DELIVERY SYSTEM: A COMPREHENSIVE REVIEW
Authors: Venkatesh D. Nagasamy , Kiran H. C , Shashikumar S. , Indurekha V. , Subramaniam K. J Thirumalai , Rani A. Uma
Published: January 2025

Dendrimers are synthetic, highly branched, monodisperse macromolecules of nanometer dimensions with exact and large number of functional groups, distributed with unprecedented control, makes them a promising scaffolds, for drug delivery. Dendrimers serves as an ideal vehicle for cancer therapy, immunology, vaccines, antivirals, biosensors for diagnostics, neuron capture therapy, photodynamic therapy and photo thermal therapy. Dendrimers chemistry is one of the most fascinating and rapidly expanding areas in the field of chemistry. Prior to the dendrimer technology, nanoparticle drug delivery systems were one of the choicest systems owing to their selectivity and stability of therapeutic agents incorporated into the system. However, few drawbacks such as reticuloendothelial system (RES) uptake, drug leakage, immunogenicity, hemolytic toxicity, cytotoxicity, hydrophobicity etc., impede the usage of these nanostructures. Further, these shortcomings shall be circumvented by modifying the surface engineering, such as poly ester dendrimer, arginine dendrimer, glycol dendrimer, PEGylated dendrimers etc., Unique properties of uniform size, water solubility, modifiable surface functionality and availability of internal cavities makes them intriguing carrier for biological and drug delivery system. In the present review, we focused on the bioactive agents that can be easily encapsulated into the interior cavity (or) chemical attachment, conjugation (or) physically adsorbed on to the dendrimer surface to serve the desired properties of the carrier to cater specific needs of the active components, its characterization and application.
CHOOSING AN APPROPRIATE METHOD FOR SUSTAINED RELEASE FLURBIPROFEN PELLET PRODUCTION
Authors: Zenginer S. , Pehlivan Akalin N. , Turkyilmaz A.
Published: January 2025

Flurbiprofen is a slightly water soluble, nonsteroidal anti-inflammatory active ingredient with analgesic and antipyretic activity. The purpose of this study was to develop an appropriate pellet production method for pH independent sustained release pellet formulation of flurbiprofen. Flurbiprofen pellets were produced by three different production methods; Suspension Layering, Extrusion Spherization, Rotagranulation. Although the simple and fast processing properties of Extrusion Spheronization and Rotagranulation methods, according to visual control and comparative dissolution profiles, Suspension Layering method was found more suitable for Flurbiprofen SR (Sustained Release) having high drug load for each single dose. Beginning with the spherical core has brought great advantage to Suspension Layering method, since ideal sphericity could not be reached at Extrusion Spheronization and Rotagranulation methods due to limited microcrystalline cellulose amount.
WOUND HEALING, PHYTOCHEMICAL AND ANTIMICROBIAL PROPERTIES OF LUFFA CYLINDRICA (LINN.) SEED EXTRACTS
Authors: Antia Bassey S. , Essien Emmanuel E. , Okokon Jude E. , Alalade Iyiade G.
Published: January 2025

The study investigates the wound healing and antimicrobial activities of extracts from Luffa cylindrica (Linn) seeds. The seed extracts (n-hexane, chloroform, diethyl ether, ethyl acetate, butanol and methanol) were evaluated for wound healing properties in white albino rats using the full thickness skin excision model. Thirty-two female wistar albino rats were randomly divided into four groups. Animals in the test groups were treated topically with 1 ml of 200mg/ml of the extracts for 17 days post-surgery. The standard and control groups were treated with Neobacin® powder (neomycin and bacitracin) and sterile distilled water respectively. Significant (P<0.05) wound contractions were observed across the groups. Diethyl ether extract had the most prominent wound healing activity while chloroform was least active. The median lethal dose (LD50) of the methanol seed extract administered intraperitoneally in wistar albino mice was found to be 24.5 mg/kg. Different concentrations of the various extracts of L. cylindrica seeds were evaluated for antimicrobial activity against selected wound pathogens (Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumonia, Escherichia coli, Proteus vulgaris and Candida albicans) using agar well diffusion method and the minimum inhibitory concentrations (MIC) of each were determined. The seed extracts were active against gram positive, gram negative and fungus; the M.I.C. of various extracts of seeds extracts range from 0.04-0.6 g/ml. Furthermore, phytochemical studies revealed the presence of saponins, tannins, flavonoids, carbohydrates, cardiac glycosides, deoxy-sugar, terpenes, phlobatannins and alkaloid. The way the different extracts functioned on the selected wound pathogens depended on the phytochemicals present in the extract.
DEVELOPMENT AND VALIDATION OF STABILITY INDICTING ASSAY METHOD FOR THE SIMULTANEOUS ESTIMATION OF OFLOXACIN AND ORNIDAZOLE IN TABLET DOSAGE FORM BY UPLC
Authors: Patel Parth U. , Pasa T. Y. , Thakor Khushbu A. , Chauhan Ruchita J.
Published: January 2025

A stability indicating RP-UPLC method was developed and validated for simultaneous estimation Ofloxacin and Ornidazole in tablet dosage form. The separation was achieved under optimized chromatographic condition on a Waters® C18 Acquity UPLC BEH (100 mm × 2.1 mm, 1.7μm) column with mobile phase consist of Water: Acetonitrile: Triethylamine in the ratio of 85: 15: 0.1 v/v. An isocratic elution at a flow rate of 0.2 ml/min at ambient oven temperature was carried out with PDA detection at 300 nm. The retention time for Ofloxacin and Ornidazole was 3.9 min and 6.4 min respectively. The degradation was observed under acidic, alkali, oxidative, photolytic and thermal conditions. The linearity was found to be in the concentration range of 50-150μg/ml for Ofloxacin and 125-375μg/ml for Ornidazole. The % recoveries at 50% were found to be 100.46% & 100.22% for Ofloxacin & Ornidazole respectively. The % recoveries at 100% were found to be 99.70% & 99.83% for Ofloxacin & Ornidazole respectively. The % recoveries at 150% were found to be 99.67% & 100.30% for Ofloxacin & Ornidazole respectively. The method was validated as per ICH guideline and the values were found to be within the limits. So, the proposed method was found to be simple, linear, accurate, precise, stability indicating, robust and specific.
Diario de la pandemia: consolidación de la apuesta editorial de la Revista de la Universidad de México
Authors: Hernández Acosta Miguel Ángel
Published: January 2025

Con su llegada a la dirección de la Revista de la Universidad de México, en mayo de 2017, Guadalupe Nettel transformó dicha publicación: su materialidad, sus contenidos y su línea editorial. Tres años después, con la edición del libro Diario de la pandemia, en septiembre de 2020, consolidó dicho proyecto y se clarificó su apuesta cultural. Proponemos realizar una lectura extensiva de los 41 números de la revista en este periodo, además de una revisión minuciosa y en paralelo del libro para mostrar/comparar las características de la publicación universitaria, así como de sus políticas editoriales, a la luz de lo que se revela como constantes.
Diario de la pandemia: Consolidation of the Revista de la Universidad de México Editorial Commitment
Abstract
With her arrival as director of the Revista de la Universidad de México, in May 2017,
Guadalupe Nettel transformed said publication: its materiality, its contents and its editorial line. Three years later, with the publication of the book Diario de la pandemia, in September 2020, she consolidated this project and clarified her cultural commitment. We propose to carry out an extensive reading of the 41 issues of the magazine in this period, in addition to a thorough and parallel review of the book to show/compare the characteristics of the university publication, as well as its editorial policies considering what is revealed as constants.
Recibido: 17 de junio de 2024Dictaminado: 26 de septiembre de 2024Aceptado: 20 de noviembre de 2024
Nota editorial
Authors: Flores Malva , Hernández Suárez Diana
Published: January 2025

Cuando el 6 de mayo de 1894 el Duque Job publicó “Al pie de la escalera” para fundar su Revista Azul bajo un programa sin programa –“¿Qué hay de común entre los programas y nosotros? ¿Tenemos acaso tiesura y traza de ministros?”–, insistió en que la publicación no tenía más finalidad que la de ser una casa para la Belleza –la loca de la casa– que necesitaba un espacio para mostrarse. Al pie de la escalera de su casa azul, Gutiérrez Nájera dio la bienvenida al lector de revistas habiéndole dado a la belleza una morada: “Para la ‘loca de la casa’ no teníamos casa y por eso fundamos esta Revista Azul.”
LA INCLUSIÓN DE LA NOCIÓN DE INTERCULTURALIDAD AL PROGRAMA DE LA ASIGNATURA DIDÁCTICA GENERAL EN LA FORMACIÓN DOCENTE UNIVERSITARIA
Authors: Ramírez Paula
Published: January 2025

En este artículo se comparten reflexiones en torno a la incorporación de la noción de interculturalidad al programa de Didáctica General de las Carreras de Formación Docente del Centro Regional Universitario Bariloche (CRUB) de la Universidad Nacional del Comahue (UNCo), Argentina. Se plantea la interculturalidad como un nuevo tema en la agenda de la Didáctica General, en tanto dicha noción interpela las prácticas de enseñanza y propicia repensar las construcciones del campo de conocimiento didáctico con un sentido crítico y emancipador. La consideración del aula como espacio de reconstrucción de la cultura y de las subjetividades, la reorientación del papel del profesor, así como el descentramiento epistemológico que la interculturalidad crítica supone, son algunos de los elementos sugeridos para tener en cuenta a la hora de diseñar nuevas formas de enseñar y de aprender en los espacios educativos.
EDUCACIÓN INTERCULTURAL Y ANTIRRACISTA: UN ACERCAMIENTO DESDE LA UNIVERSIDAD CUBANA
Authors: Pons Giralt Maikel
Published: January 2025

La revolución cubana minó las bases estructurales del racismo heredado de la sociedad capitalista. Sin embargo, la realidad educativa universitaria cubana evidencia la presencia de estereotipos negativos en profesores y estudiantes, especialmente hacia los negros (as) y el legado cultural africano. Esto se constata en representaciones sociales negativas y el insuficiente conocimiento y tratamiento intercultural que se recibe en la formación de pregrado y posgrado sobre los diferentes componentes étnicos-culturales de la nación cubana. En este artículo se brinda un análisis sobre los antecedentes en la pedagogía cubana, con respecto al fomento de valores interculturales en la preparación, tratamiento y actuación de los docentes, enfocados en los componentes étnicos/raciales de la cultura cubana. Se realiza además una caracterización epistemológica del proceso de educación intercultural y de la educación antirracista en la educación superior cubana.  Los principales métodos y técnicas empleados en la investigación son la revisión documental, el análisis de contenido, la observación, entrevistas, encuestas y grupos focales. Esta investigación ya permite resultados que se concretan en la producción científica y tecnológica, específicamente en publicaciones, participación en eventos, intercambio de experiencias y modelación de proyectos, cursos, tesis de pregrado, maestrías y doctorado que tributan a la temática.
PERSPECTIVAS DE DERECHOS HUMANOS EMERGENTES EN LOS DISCURSOS DE LA EDUCACIÓN PARA LA PRIMERA INFANCIA
Authors: Ochoa Serna Paula Andrea , Gallardo – Cerón Blanca Nelly
Published: January 2025

Las perspectivas frente a los derechos humanos no se reducen a una sola mirada; actualmente su concepción es amplia y diversa, vale la pena aclarar que no son una lista inacabada, o ideales de difícil acceso y cumplimiento. El presente artículo deriva de la investigación Análisis de las perspectivas de derechos humanos emergentes en los discursos de la educación para la primera infancia, y que orientó su objetivo principal a buscar la respuesta a la pregunta de investigación ¿Cuáles son las perspectivas de derechos humanos emergentes en los discursos normativos y educativos que orientan las prácticas de la primera infancia en la Institución educativa Reino de Bélgica Municipio de Medellín Colombia? Como ruta metodológica se acude al análisis documental, la entrevista y el grupo de discusión llevados a cabo en el marco del Análisis Crítico del Discurso basado en la propuesta de Fairclough, para el reconocimiento y la constitución de subjetividades frente a los derechos humanos presentes en los discursos que guían las prácticas de la primera infancia1de la ciudad de Medellín, y en cuyos hallazgos se encontró que la infancia y sus derechos se plantean desde la igualdad y la universalidad como fuente de su singularización, lo que tiene como consecuencia  una infancia asistida, y no escuchada.
LA DIVERSIDAD CULTURAL EN AMÉRICA LATINA. UN PROBLEMA ÉTICO POLÍTICO PARA LA FORMACIÓN Y LA PRODUCCIÓN DE CONOCIMIENTO
Authors: Quintar Estela Beatriz
Published: January 2025

Un proyecto de recuperación de los sujetos es lo que se concibe como tarea de la formación, y en eso una dimensión fundamental es la cultura. Los sistemas educativos en América Latina están históricamente orientados a la homogenización cultural de sus integrantes. Una propuesta que retome la diversidad cultural en los procesos de formación es indispensable desde la perspectiva política de la educación para producir conocimiento histórico.
CRUZANDO LOS LÍMITES ENTRE LA ESCUELA, SU COMUNIDAD LOCAL Y EL ESTADO. HISTORIAS VIVIDAS Y CONTADAS POR PROFESORAS CHILENAS
Authors: González Calderón Fabián Enrique , Cavieres Fernández Eduardo
Published: January 2025

En este artículo contamos las historias de un grupo de escuelas surgidas en la comuna de La Reina en el contexto de la expansión masiva de la escuela pública en Chile (1963 – 1983). Las protagonistas de estas historias son maestras de Educación Básica que casi sin proponérselo, y por efecto de sus trayectorias personales, resumen en sus vidas profesionales la memoria local de la escuela pública en contextos de pobreza y precariedad. La historia que presentamos es el resultado de dos etapas de investigación llevadas a cabo entre 2011 y 2012. Las fuentes utilizadas incluyen relatos biográficos escritos por ocho profesoras, consulta a periódicos nacionales y locales, y entrevistas individuales y en profundidad a 4 profesoras. El propósito de nuestro trabajo es comprender, desde la cotidianidad vivida, de qué manera las reformas educativas afectan o son resistidas por quienes habitan las escuelas, de modo de conocer aspectos de la vida de estas escuelas que en el relato construido a partir de las políticas educativas han quedado silenciados. En la discusión proponemos algunos ámbitos de análisis como la cotidianidad de la escuela versus el poder estatal, la autonomía de los actores educativos, y la relación entre la comunidad y el territorio local, con la finalidad de releer las historias contadas y las políticas educativas dominantes en la actualidad.
LA CORPORALIDAD EN EL DISPOSITIVO ÁULICO UNIVERSITARIO
Authors: Bonvillani Andrea
Published: January 2025

Este artículo reflexiona sobre la dimensión de la corporalidad en la experiencia de enseñar y aprender en el ámbito universitario.  Aunque relevante en una comprensión integral de las vivencias humanas, la misma no ha sido suficientemente considerada, en especial en el nivel superior-universitario. Recuperando registros de clases realizados por la autora, así como por otros integrantes de una materia de la carrera de Psicología, en la Universidad Nacional de Córdoba (Argentina) y de los propios estudiantes cursantes, a través de un análisis cualitativo, se propone responder a las siguientes preguntas: ¿qué permite poner en visibilidad el dispositivo áulico universitario acerca de la corporalidad de los participantes? Consecuentemente, ¿qué invisibiliza?; ¿qué sucede cuando en la universidad se trabaja desde sensaciones corporales, a partir del encuentro con uno mismo y con los otros, como experiencia que posibilita la construcción de saberes? En conclusión se propone que el dispositivo áulico universitario produce disciplinamientos en la corporalidad de estudiantes y profesores, pero también aloja pliegues donde es posible algún gesto emancipatorio. Este logro depende, en parte, de la escucha de los sentires silenciados.
CAMINAR HACIA UNA PEDAGOGÍA EMANCIPADORA: REFLEXIONES RECIENTES SOBRE EL POTENCIAL DECOLONIAL DE LOS ESPACIOS EDUCATIVOS EN ORGANIZACIONES SOCIALES. JUJUY-ARGENTINA
Authors: Patagua Patricia Evengelina , Zinger Sabrina
Published: January 2025

El presente escrito pretende aportar al movimiento pedagógico latinoamericano desde nuestra experiencia de docencia, investigación y extensión en la FHyCS-UNJU. Nuestro trabajo compartido con organizaciones y movimientos populares; y con el estudiantado de la Carrera en Ciencias de la Educación, nos llevaron a optar por las posiciones éticas, políticas, epistemológicas y metodológicas de la Educación Popular Latinoamericana (EP) y la Investigación Acción Participativa (IAP).
Entre las pesquisas más importantes de las investigaciones realizadas en los movimientos se destaca el carácter alternativo de su producción cultural en las dimensiones de lo territorial, lo colectivo y lo autónomo. Este componente de alternatividad nos exigió el diálogo entre las perspectivas ya incorporadas y el pensamiento decolonial, tanto para develar aspectos ocultos en “otras” dimensiones de dominación; como para reconocer y reposicionar pedagógicamente la vida de movimiento (Zibehci 2009).
Entonces en este trabajo retomamos las tradiciones críticas de la EP y la IAP; y nos proponemos enriquecerlas con los aportes que le hace el pensamiento decolonial al campo pedagógico. Nos centramos en la relación analítica entre la noción de espacios educativos (Gramsci, A., 1988) y las reflexiones sobre las marcas de la colonialidad y la modernidad en educación (Fernández Moujan, 2010).
Palabras claves:  decolonización-espacios educativo-modernidad-colonialidad
EXPERIENCIAS FORMATIVAS DE EDUCACIÓN INDÍGENA EN COLOMBIA Y CHILE: UN APORTE A LA EDUCACIÓN INTERCULTURAL LATINOAMERICANA
Authors: Calderón Leyton Elia
Published: January 2025

Este artículo se basa en el análisis de la interculturalidad y la Pedagogía intercultural que se han creado en Latinoamérica para dar respuesta a la demanda en educación intercultural, haciendo referencia a los pueblos indígenas y afrodescendientes en Latinoamérica. El objetivo de este artículo es presentar el curso en el programa de formación de profesores indígenas de la Licenciatura en Pedagogía de la Madre Tierra (LPMT) de la Universidad de Antioquia, Colombia y la formación práctica de formación inicial docente en educación básica intercultural de la Universidad Católica de Temuco.  El problema que se discute es la confrontación de saberes y conocimientos de personas pertenecientes a esferas culturales diferentes, en el marco de la educación intercultural en el contexto latinoamericano. Por último, se plantean posibles soluciones para mejorar la educación intercultural y lograr su revitalización.
HACIA UNA PROPUESTA PARA EL FOMENTO DE LA LECTURA LITERARIA EN LOS/AS JÓVENES DESDE EL INTERTEXTO, EL HIPERTEXTO Y LA NARRATIVA TRANSMEDIA
Authors: Hinojosa Hugo
Published: January 2025

En una sociedad que avanza rápidamente en su desarrollo tecnológico y digital, cada vez toma más fuerza el hecho tangible de que los textos literarios —particularmente los narrativos— ya no pueden concebirse de la misma manera. Esto nos obliga a hacernos preguntas relevantes frente al nuevo panorama que se configura ¿Qué ocurre, por ejemplo, con el canon literario actual y las nuevas imágenes recibidas por los jóvenes a través del cine, los cómics, la televisión o Internet?Este artículo se presenta como una propuesta didáctica frente a este proceso en avance, lo que nos obliga a reflexionar y replantear nuestros enfoques sobre el fenómeno literario, asumiendo cómo las obras dirigidas a un público juvenil, los cómics y otros formatos, análogos como digitales, van ganando cada vez más adeptos entre los/as más jóvenes, y tensionan la discusión sobre los géneros y los límites de la literatura y, en definitiva, el canon de lo que debe ser leído en la escuela. Se trata de espacios mediales apropiados por niños/as, adolescentes y jóvenes, que ven en estas posibilidades la ampliación de sus intereses.De este modo, conceptos como intertextualidad y transmedialidad se vuelven mucho más importantes como referencia para los cambios importantes que se están produciendo en el ámbito lector juvenil. En efecto, actualmente, hay lectores/as que reseñan, critican y también producen literatura. Este trabajo pretende ser un breve marco didáctico para comprender los nuevos desafíos que implica la literatura desde el frente de los adolescentes y jóvenes, proponiendo a su vez un modelo procedimental basado en tres etapas: Especificar, Relacionar y Proyectar.
RESOLUCIONES DE UNA TAREA DE CÁLCULO POR PARTE DE PROFESORES DE MATEMÁTICAS. ¿CUÁLES SON LOS ARGUMENTOS QUE ELLOS VALIDAN TANTO EN SU TRABAJO PERSONAL COMO EN EL AULA?
Authors: Menares Romina
Published: January 2025

En este artículo presentamos diferentes maneras de enfrentar un problema de cálculo por parte de profesores de secundaria en ejercicio en el sistema escolar chileno. Nuestro objetivo es indagar en procesos de visualización, distintos instrumentos utilizados y argumentos que profesores despliegan al resolver o dar respuesta a un problema. Además, buscamos conocer cuáles son los argumentos que los profesores validan dentro del desarrollo de problemas que demandan procesos argumentativos, tanto en su propio trabajo con el problema, como el posible trabajo en el aula. La investigación es cualitativa y se realiza bajo la perspectiva teórica de los Espacios de Trabajo Matemático (ETM). El estudio nos permite evidenciar diferentes recursos utilizados por los profesores para la resolución del problema, reconocer los discursos matemáticamente aceptados por los docentes, y observar qué significa para el grupo de profesores la justificación de un conocimiento matemático.
Palabras clave: Espacio de Trabajo Matemático, visualización, argumentación, profesores de secundaria.
¿Se asocia la calidad de las tesinas a la selectividad?:
Authors: Espinoza Oscar , González Fiegehen Luis , Sandoval Luis , Loyola Javier
Published: January 2025

La selectividad de las universidades otorga información relevante para ponderar su calidad. Se esperaría que la mayor o menor calidad del proceso formativo abarque todos los aspectos académicos, incluyendo las tesinas desarrolladas por estudiantes que cursan carreras de pregrado. La investigación que se reporta en este artículo tuvo por objetivo evaluar la calidad de las tesinas en carreras de Psicología en tres universidades chilenas con distintos niveles de selectividad. El estudio apela al juicio de expertos para evaluar la calidad de las tesinas. Los resultados revelan que el nivel de selectividad está asociado parcialmente a la mayor calidad de las tesinas y, por ende, al proceso formativo en el caso de las carreras de Psicología. No existe evidencia suficiente que confirme completamente el supuesto central de este estudio, vale decir, que mayores niveles de selectividad y años de acreditación institucional se corresponden con tesinas de mayor calidad, y viceversa.
Pengaruh Susunan Rak terhadap Distribusi Kecepatan dan Suhu pada Pengering Tipe Rak (Tray Dryer): Simulasi dengan Menggunakan CFD
Authors: Gusriwandi  , Putri Rahayu Muhlita , Pratoto Adjar
Published: January 2025

Tray dryers have been being used widely due to its simplicity in construction and a relatively low operational cost. One of the main drawbacks of the tray dryers lies in the non-uniformity in the dryness of the products over the trays. This article dealt with the numerical investigation of the flow anf temperature distribution inside the drying chamber as impacted by by trays’ arrangement. Three trays’ arrangements were considered in the study, i.e. parallel, serpentine-like, and parallelepepid. The simulation was carried out with no load. The drying chamber is modeled as a box of 0,51 m long, 0,51 m wide, and 0,96 high. The dryer consists of 5 trays, each of 0,50 m, 0,40 m wide, and 0,005 m thick. The vertical distance from one tray to another is 0,168 m. The parameter input includes: drying air velocity and temperature at the dryer inlet are 1 m/s and 50oC respectively, while the surrounding air temperature is constant at 27oC. From the simulation, it can be revealed that the serpentine-like trays’ arrangement provides most uniform velocity and temperature distribution as compared to those of the other two trays’ arrangement. The relatively uniform distribution can be achieved until the fourth tray for the serpentine-like and the parallellpepid arrangements; while the parallel arrangement reaches only the third tray.
Pembuatan Gigi Pemotong Bola Biofilter Tanah Liat
Authors: Ridwan Firman , Havendri Adly
Published: January 2025

It cannot be denied that technological developments from year to year are growing very rapidly. One technology that is feasible to be developed in the fishing industry today is clay ball biofilter technology. Clayball biofilter is a filter or biological filter that functions in an aquatic ecosystem, both small ecosystems such as aquariums and large ecosystems such as fish ponds so that the water conditions of an aquatic ecosystem can remain clean longer than usual. Biofilters are also useful for fish farming workers to minimize the energy and costs of replacing water ecosystem filters which must be replaced regularly. Clayball biofilter media is round and made from clay which is shaped like small balls. The aim of this research is to make cutting gear components for clay ball biofilter production machines using a casting process. Making patterns from cutting tools using 3D printing then making molds until the metal casting process is carried out. Based on research results, equipment made with 3D printed patterns has a better shape compared to patterns made using wax. By adjusting the pitch distance of the cutting tool, the size of the clayball biofilter can make the ball size of the biofilter product 17 mm in diameter.
Kajian Peningkatan Ketangguhan Retak Material Komposit dari Poliester Tak Jenuh dengan Penguatan Serat Ampas Tebu
Authors: Nusyirwan  , Hizhar Yul , Malik Adam
Published: January 2025

The development of environmentally friendly composites must be carried out to reduce or replace synthetic composites that are difficult to decompose. However, composite materials from natural fibers still have several weaknesses, such as low mechanical strength, brittleness and easy cracking. This research mixed unsaturated polyester reinforced with natural fiber from sugarcane bagasse. Determination of the critical stress intensity factor was carried out based on ASTM D 5405 by varying the composition of the sugarcane bagasse fiber mixture from 10% to 30%. The test results showed that the largest critical stress intensity factor (K1c) was 1.624 MPa/m0.5 for 20% sugarcane bagasse fiber.
Analisis Laju Keausan Cylinder Liner pada Mesin Diesel
Authors: Yuliandra Berry , Aji Adhitya Purnama
Published: January 2025

Diesel engines play an important role in land transportation vehicles, such as trucks. Cylinder liner is a component of diesel engine that functions to protect cylinder block from friction with the piston ring. One of the common failures of this component is wear. Wear measurement is an important procedure in the maintenance process. This study aims to measure the wear rate of cylinder liners in diesel engine maintenance. The measurement results show that uneven wear occurs on each cylinder liner. Cylinder liner 3 experienced the greatest wear, which was 7429.02 mm3 with a wear rate of 0.675 mm3/hour. Cylinder liner 4 experienced the smallest wear, which was 2307.46 mm3 with a wear rate of 0.210 mm3/hour. The main cause of this is uneven lubrication and abnormal injection nozzles so that explosions occur unequally in each cylinder.
Indicações e benefícios da terapia de reposição hormonal no climatério
Authors: Soares Mylena Tenório , Peres Amanda Barbosa , Ximendes Carolina Martins , Viana Giovana Santos , Tokarski Igor Caminha , Colomietz Isabella Ferreira , Guedes Isabella Paraguassu de Almeida , Guimarães Letícia Carvalho , Coelho Rachel Araújo Gonçalves , Esteves Paulo Lisbão de Carvalho
Published: January 2025

Objetivo: Analisar as indicações e benefícios da Terapia de Reposição Hormonal (TRH) durante o climatério. Revisão Bibliográfica: A menopausa marca o declínio da função reprodutiva feminina, definida pela ausência de menstruação por pelo menos 12 meses, retrospectivamente, que ocorre devido à insuficiência ovariana primária, geralmente entre 45 e 55 anos. Além de elevar o risco de condições crônicas, como doenças cardiovasculares, a falta de estrogênio neste período também está associada à osteoporose. Esta revisão tem como principal objetivo analisar as indicações e benefícios da terapia de reposição hormonal no climatério. Nesse cenário, a TRH configura uma abordagem eficiente para o manejo de sintomas vasomotores e genitourinários que ocorrem nesta fase, além de apresentar benefícios na saúde cardiovascular e óssea de mulheres que se encontram na janela de oportunidade. Apesar disso, a terapia hormonal pode apresentar contraindicações, como o uso em pacientes com história familiar de câncer de mama e de endométrio, por exemplo. Considerações Finais: Esta terapêutica deve ser individualizada, considerando preferências pessoais e indicações clínicas adequadas, de forma a maximizar seus benefícios.
Uma análise dos aspectos clínicos da Apneia Obstrutiva do Sono
Authors: Medeiros Raniellen Carvalho de , Sousa Natália Barreto e
Published: January 2025

Objetivo: Explorar as características clínicas da Apneia Obstrutiva do Sono (AOS). Revisão bibliográfica: A AOS é uma condição definida pelo bloqueio das vias aéreas durante o sono, levando a episódios de apneia ou hipopneia, que precisam ter a duração de pelo menos 10 segundos. Essas pausas respiratórias causam uma hipóxia intermitente (HI) que geram diversas consequências no organismo e corroboram com o aparecimento de doenças cardiovasculares e diabetes mellitus tipo 2 (DM 2). Os principais sintomas são ronco persistente e sonolência diurna excessiva (SDE), que afetam diretamente a qualidade de vida do paciente acometido. Os principais fatores de risco são obesidade e anormalidades anatômicas craniofaciais. O diagnóstico é feito por dados clínicos e realização de polissonografia (PSG). O tratamento padrão-ouro é o uso de um dispositivo de pressão positiva contínua nas vias aéreas (CPAP), mas sua eficácia depende da adesão. Considerações finais: Pode se considerar que diagnóstico e o tratamento multidisciplinar são essenciais para o manejo adequado da AOS com o objetivo de aprimorar o bem-estar e a qualidade de vida dos pacientes acometidos por essa patologia.
Intervention strategy for Rapid Grower Mycobacteria outbreak among post-laparoscopic surgical site infection patients in a tertiary care hospital
Authors: Pal Nupur , Ray Raja , Kundu Somenath , Maiti Prasanta Kumar
Published: January 2025

Background & objectives

The emergence of Rapid Grower Mycobacteria (RGM) infections recently produced a great challenge among surgeons following laparoscopic surgical site infection. Infections caused by atypical mycobacteria may be overlooked due to limitations of proper diagnostic infrastructure and unawareness in the resource-limited set-up. In this study, we proposed an intervention strategy for RGM infection among patients having post-laparoscopic surgical site infections in our hospital.

Methods

Five hundred sixty-five samples were collected within one year (April 2018- March 2019) from the surgery outpatient department (OPD), suspecting atypical mycobacteria infection following surgery. Samples were processed in the microbiology department by conventional staining and culture. RGM was diagnosed up to the species level by both conventional and molecular methods [line probe assay (LPA)]. The antibiogram was performed by the microbroth dilution method on the RAPMYCOI kit as per Clinical and Laboratory Standard Institute (CLSI) guidelines. Simultaneous source identification was carried out.

Results

A biofilm-producing Mycobacterium abscessus strain was detected from the plastic disinfection tray of the surgical operation theatre (OT), which may be the continuous source of iatrogenic post-surgical infection. RGM prevalence among suspected patients was 19.47 per cent, and around 92 per cent of them were from laparoscopic surgery. Antibiotic sensitivity, as per CLSI guidelines, showed most of them (88.8%) were resistant to commonly given antibiotic clarithromycin. Most sensitivity was to antibiotics amikacin, tobramycin, moxifloxacin, and doxycycline. The game-changing intervention related to this outbreak scenario was the introduction of gas-plasma sterilization and maintaining strict asepsis in surgical operation theatre.

Interpretation & conclusions

Based on the analysed data, we proposed an intervention strategy in our hospital for treating and preventing RGM infection. Such an approach will help arrest the RGM-outbreaks in future.
Difusi Inovasi Dakwah Digital pada Komunitas @Remisyaofficial di Instagram dalam Mempersuasi Program Dakwah di Kalangan Remaja
Authors: Saidah Musfiah , Irmayanti Ade
Published: January 2025

Perkembangan teknologi komunikasi dan informasi pada era digital ini telah mempengaruhi berbagai aspek kehidupan manusia, terutama dalam memperoleh informasi. Berbagai inovasi telekomunikasi pun semakin banyak, apalagi tersedia akses internet dan media sosial. Salah satu platform media sosial yang popular di kalangan masyarakat Indonesia, khususnya generasi muda dan remaja adalah Instagram. Instagram memberikan kemudahan bagi penggunanya untuk saling berinteraksi dan berbagi informasi, termasuk informasi dakwah. Seperti yang dilakukan oleh komunitas Remisya, yang memanfaatkan Instagram sebagai sarana untuk menyebarkan informasi dakwah. Oleh karena itu, penelitian ini bertujuan untuk menganalisis proses difusi inovasi dakwah digital pada komunitas Remisya dalam mempersuasi remaja di Instagram. Penelitian ini menggunakan metode kualitatif dengan pendekatan fenomenologi, dan paradigma konstruktivis. Adapun, data penelitian ini diperoleh  melalui observasi, wawancara mendalam dan dokumentasi. Sementara, teori difusi inovasi yang diperkenalkan oleh Everett M. Rogers digunakan sebagai alat analisis untuk memahami bagaimana Instagram diadopsi oleh komunitas Remisya dalam menyebarkan informasi dakwah. Hasil penelitian ini menunjukkan bahwa proses difusi inovasi dakwah digital pada komunitas Remisya mampu mempersuasi remaja untuk mengikuti program dakwah mereka. Dengan memperhatikan beberapa elemen difusi inovasi dan proses pengambilan keputusan inovasi yang melibatkan beberapa tahapan, termasuk juga kemampuan komunitas Remisya dalam mengadopsi dan beradaptasi dengan teknologi digital untuk tujuan dakwah.
The Role of User-Generated Content in Shaping Consumer Trust: A Communication Psychology Approach to E-commerce
Authors: Alamyar Iqbal Hussain
Published: January 2025

User-Generated Content (UGC) plays a vital role in shaping consumer trust within the dynamic realm of e-commerce. This study explores the psychological mechanisms through which UGC influences trust, employing a communication psychology approach. Using qualitative interviews with frequent e-commerce users, the research investigates how UGC impacts trust and the psychological factors involved. Thematic analysis of participant responses revealed key themes, including perceived authenticity, community engagement, and content creator relatability. Participants emphasized that genuine and relatable UGC enhances transparency and trustworthiness, setting it apart from traditional advertising. Additionally, social proof and cognitive biases were found to significantly influence trust formation. Findings suggest that e-commerce platforms can enhance consumer trust by fostering authentic UGC and encouraging active community engagement. This research provides valuable insights into the interaction between digital content and consumer behavior, offering practical strategies for leveraging UGC, such as promoting genuine user participation and integrating UGC into marketing efforts. This study highlights the critical role of UGC in building trust in e-commerce, contributing to the theoretical framework of communication psychology while bridging the gap between theory and practice.