bluuebunny/crossref_metadata_2025 huggingface dataset:
Vortices in Polar and β Phases of 3He
Authors: Volovik G. E.
Published: March 2022

Recently, a new topological phase of superfluid 3He called the β phase has been obtained by strong polarization of the nematic polar phase. We consider half-quantum vortices, which are formed in rotating cryostat, and discuss the evolution of the vortex lattice in the process of the transition from the polar phase to the β phase via the spin-polarized polar phase.
Cerebrospinal fluid fistula after combined spinal-epidural block
Authors: Pereira Ana Isabel , Fernandes Diana Lastra , Amorim Ana , Nunes Sara
Published: March 2022

Neuraxial anaesthesia is an essential technique in obstetric anaesthesia practice. Cerebrospinal fluid (CSF) fistula is a rare complication and there is no consensus about its clinical approach. We present a case of a 28-year-old nulliparous woman that developed a cutaneous CSF fistula following combined spinal and epidural block for caesarean delivery. After multidisciplinary discussion it was decided that hydration, absolute bed-rest and compressive dressing with abdominal binder was the best option and the patient fully recovered without any sequelae.

Based on literature, symptoms of intracranial hypotension and leakage of clear fluid surrounding the puncture site usually motivate referral to anaesthesia. Management strategies can be both conservative and invasive, including direct suture of the skin puncture site and epidural blood patch.

Regarding the anaesthesia practice on this topic, most of the available evidence is based on case reports, rendering the decision-making process challenging.
Olanzapine-induced acute necrotising pancreatitis leading to recurrent multiple organ dysfunction syndrome
Authors: Naxakis Stelios , Wafer Meghan , Collins Ruth
Published: March 2022

A married mother in her 50s acutely developed vomiting, diarrhoea and severe epigastric pain 2 weeks following discharge from an acute psychiatric inpatient unit. She presented to the emergency department complaining of a 2-day history of the above symptoms. Blood tests revealed neutrophilia, grossly raised inflammatory markers and amylase levels triple the normal range. Based on radiological investigations, she was treated for necrotising pancreatitis that quickly escalated to multi-system organ failure and a lengthy intensive care unit admission. Common causes of pancreatitis, including cholelithiasis, alcohol and other drugs, were ruled out. Despite this, she suffered recurrent episodes of pancreatitis with significant morbidity. Olanzapine, started during her psychiatric admission, was determined to be the offending agent. Two years following the discontinuation of olanzapine, the patient has had no further episodes of acute pancreatitis.
Characterising acute ischaemic stroke thrombi: insights from histology, imaging and emerging impedance-based technologies
Authors: Patil Smita , Darcourt Jean , Messina Pierluca , Bozsak Franz , Cognard Christophe , Doyle Karen
Published: March 2022

Treatment of acute ischaemic stroke (AIS) focuses on rapid recanalisation of the occluded artery. In recent years, advent of mechanical thrombectomy devices and new procedures have accelerated the analysis of thrombi retrieved during the endovascular thrombectomy procedure. Despite ongoing developments and progress in AIS imaging techniques, it is not yet possible to conclude definitively regarding thrombus characteristics that could advise on the probable efficacy of thrombolysis or thrombectomy in advance of treatment. Intraprocedural devices with dignostic capabilities or new clinical imaging approaches are needed for better treatment of AIS patients. In this review, what is known about the composition of the thrombi that cause strokes and the evidence that thrombus composition has an impact on success of acute stroke treatment has been examined. This review also discusses the evidence that AIS thrombus composition varies with aetiology, questioning if suspected aetiology could be a useful indicator to stroke physicians to help decide the best acute course of treatment. Furthermore, this review discusses the evidence that current widely used radiological imaging tools can predict thrombus composition. Further use of new emerging technologies based on bioimpedance, as imaging modalities for diagnosing AIS and new medical device tools for detecting thrombus composition in situ has been introduced. Whether bioimpedance would be beneficial for gaining new insights into in situ thrombus composition that could guide choice of optimum treatment approach is also reviewed.
Addressing lower-priced cigarette products through three-pronged comprehensive regulation on excise taxes, minimum price policies and restrictions on price promotions
Authors: Ribisl Kurt M , Golden Shelley Diane , Huang Jidong , Scollo Michelle
Published: March 2022

The prices that smokers pay out-of-pocket for their tobacco products ultimately influence their smoking behaviour. Although cigarette excise taxes are arguably the best and most used policy to increase cigarette prices, taxes are only one component of retail cigarette prices. The persistence of lower-priced products, disproportionately purchased by lower-income smokers, in jurisdictions with high excise taxes is an Achilles heel for tobacco tax policy. When governments raise excise taxes, the tobacco industry responds. The industry reduces tax pass-through to minimise the price increases for lower-priced brands and offers price discounts to retailers and coupons to consumers. In addition, smokers who do not quit after tax increases may downshift brands, purchase in bulk or substitute lower-priced tobacco product types. This may be particularly true for price-sensitive smokers, including those with lower incomes. We propose that raising excise taxes will be more effective in reducing the persistence of lower-priced products and income-based smoking disparities when taxes are designed to raise prices frequently and substantially for all products and are combined with (a) minimum price laws and (b) bans on coupons, discounts and other promotions. In combination, these three complementary policies restrict the tobacco industry’s ability to undermine the impact of higher excise taxes upon consumer prices. Very few jurisdictions have implemented comprehensive three-pronged tobacco price regulation, but doing so would likely address many of the limitations that come with a sole focus on raising excise taxes.
The role of spatial scale in drought monitoring and early warning systems: a review
Authors: Mardian Jacob
Published: March 2022

Drought is a costly natural disaster characterized by water shortages that impact water availability, agriculture, ecosystems, and the economy. The driving mechanisms of drought operate on a wide range of spatial scales, from the movement of soil water on a hillslope to global atmospheric circulation. Additionally, drought impacts vary across spatial scales, from drought induced crop stress on a specific agricultural field to widespread continental water shortages. As a result, multiscalar drought monitoring and early warning systems are needed to utilize observational data sets obtained at different spatial scales and to communicate drought impacts to various levels of decision-makers in government and industry. However, scaling must be employed to translate information across scales, either to fix incongruencies in the spatial scale of input data sets or to modify the model output scale. These scaling techniques have several challenges and limitations that hinder drought accuracy and interpretability, such as the Modifiable Areal Unit Problem (MAUP) and increased model uncertainty. This paper reviews the role of spatial scale in drought monitoring and early warning systems, the associated challenges, and techniques to minimize their impact. Finally, this review identifies several knowledge gaps and future directions.
Classification of Low and High Schizotypy Levels via Evaluation of Brain Connectivity
Authors: Zandbagleh Ahmad , Mirzakuchaki Sattar , Daliri Mohammad Reza , Premkumar Preethi , Sanei Saeid
Published: March 2022

Schizotypy is a latent cluster of personality traits that denote a vulnerability for schizophrenia or a type of spectrum disorder. The aim of the study is to investigate parametric effective brain connectivity features for classifying high versus low schizotypy (LS) status. Electroencephalography (EEG) signals are recorded from 13 high schizotypy (HS) and 11 LS participants during an emotional auditory odd-ball task. The brain connectivity signals for machine learning are taken after the settlement of event-related potentials. A multivariate autoregressive (MVAR)-based connectivity measure is estimated from the EEG signals using the directed transfer functions (DTFs) method. The values of DTF power in five standard frequency bands are used as features. The support vector machines (SVMs) revealed significant differences between HS and LS. The accuracy, specificity, and sensitivity of the results using SVM are as high as 89.21%, 90.3%, and 88.2%, respectively. Our results demonstrate that the effective brain connectivity in prefrontal/parietal and prefrontal/frontal brain regions considerably changes according to schizotypal status. These findings prove that the brain connectivity indices offer valuable biomarkers for detecting schizotypal personality. Further monitoring of the changes in DTF following the diagnosis of schizotypy may lead to the early identification of schizophrenia and other spectrum disorders.
External sources in a minimal and nonminimal CPT-odd Lorentz violating Maxwell electrodynamics
Authors: Borges L. H. C. , Ferrari A. F.
Published: March 2022

This paper is devoted to the study of interactions between stationary electromagnetic sources for the minimal and nonminimal CPT-odd photon sector of the Standard Model Extension (SME), where we search mainly for physical phenomena not present in the Maxwell electrodynamics. First, we consider the minimal CPT-odd sector, where the Lorentz violation is caused by the Carroll–Field–Jackiw (CFJ) term, namely, [Formula: see text], and we treat the Lorentz breaking parameter [Formula: see text] perturbatively up to second order. We consider effects due to the presence of point-like charges, Dirac strings and point-like dipoles. In special, we calculate the electromagnetic field produced outside the string and investigate the so-called Aharonov–Bohm bound states in Lorentz violation context. Afterwards, we consider a model where the Lorentz violation is generated by the higher-derivative version of the CFJ model, namely, [Formula: see text], which is a dimension five term of the CPT-odd sector of the nonminimal SME. For this higher-derivative model, we obtain effects up to second order in [Formula: see text] related to the presence of point-like charges and a steady current line. We use overestimated constraints for the Lorentz violation parameters in order to investigate the physical relevance of some results found in atomic systems. We also make an overestimate for the background vectors using experimental data from the atomic electric field.
FUNCTIONAL OUTCOME OF MEDIAL SUBTALAR DISLOCATION WITHOUT ARTICULAR FRACTURES
Authors: Bharwani Nandlal , Choudhary Pradeep , Jain Hemant , Raichandani Kishore , Godara Jagdish , Saxena Medhavi
Published: March 2022

Introduction: Subtalar dislocation is a rare injury around foot and ankle. Most common mode of injury is high-energy trauma (road traffic accident (RTA), fall from height (FFH) and sports activities) (Saini R, Dhillon MS, Gill SS. Congenital subtalar dislocation — a case report. Foot 19; Kaufmann RA, Davidson R, McCarthy J. Bilateral congenital subtalar dislocation: a case report. Clin. Orthop. Related Res. 397). It is commonly seen in young men and the mechanism is inversion injury in plantar-flexed foot. Medial-type dislocation is most commonly seen with incidence between 65% and 85%, as stated in various studies. Pure ligamentous injuries have shown good prognosis, which when associated with fractures can affect the functional outcome. Methods: We conducted a prospective study from 1st January 2017 to 1st December 2020 including seven patients (five males and two females) with closed medial subtalar dislocation with (1) or without fractures (6). In our study, closed reduction was performed in all the cases. At final follow-up, functional outcome was evaluated using ‘AOFAS-AHFS Score’ and radiological assessment. Results: All seven patients had good functional outcome at final follow-up and found no difficulty in doing daily routine activities. Routine clinical and radiological assessments were also done at final follow-up. All patients had complete ROM at final follow-up. Conclusion: Closed medial subtalar dislocation without significant articular fractures has good outcome in terms of function if managed properly.
The quantum moment problem for a classical random variable and a classification of interacting Fock spaces
Authors: Accardi Luigi , Lu Yun Gang
Published: March 2022

The fact that any classical random variable with all moments has a quantum decomposition allows to associate to it a family of quantum moments. On the other hand, a classical random variable may have several inequivalent quantum decompositions, which lead to the same classical, but different quantum moments. Even in the simplest Central Limit Theorems (CLT), i.e. those of Bernoulli type, there are examples in which the corresponding quantum moments converge to the canonical quantum moments of the associated classical random variable, and examples in which this is not the case. This poses the problem to find a constructive criterium that characterizes the quantum moments associated to the canonical quantum decomposition (which is unique) with respect to the other ones. Theorem [Formula: see text] of the present paper provides such a criterium. Theorem [Formula: see text] deals with the case when one knows a priori that the quantum moments come from a central limit theorem (the motivation of the present paper arose in this context). It gives only a sufficient condition, but simpler to verify than the necessary and sufficient conditions of Theorem [Formula: see text]. Theorem [Formula: see text] naturally leads to a classification of Interacting Fock Spaces (IFS) into three types. We construct examples showing that all these possibilities can effectively take place. On the way, we prove that all the best known deformations of Heisenberg commutation relations can be obtained as special cases of a general construction within the algebraic approach to the theory of orthogonal polynomials.
A Survey on Healthy Food Decision Influences Through Technological Innovations
Authors: Marshall Jermaine , Jimenez-Pazmino Priscilla , Metoyer Ronald , Chawla Nitesh V.
Published: March 2022

It is well known that unhealthy food consumption plays a significant role in dietary and lifestyle-related diseases. Therefore, it is important for researchers to examine methods that may encourage the consumer to consider healthier dietary and lifestyle habits as diseases such as obesity, heart disease, and high blood pressure remain a worldwide issue. One promising approach to influencing healthy dietary and lifestyle habits is food recommendation models that recommend food to users based on various factors such as health effects, nutrition, preferences, and daily habits. Unfortunately, much of this work has focused on individual factors such as taste preferences and often neglects to understand other factors that influence our choices. Additionally, the evaluation of technological approaches often lacks user studies in the context of intended use. In this systematic review of food choice technology, we focus on the factors that may influence food choices and how technology can play a role in supporting those choices. We also describe existing work, approaches, trends, and issues in current food choice technology and give advice for future work areas in this space.
Molecular Shape Solution for Mesoscopic Remodeling of Cellular Membranes
Authors: Bashkirov Pavel V. , Kuzmin Peter I. , Vera Lillo Javier , Frolov Vadim A.
Published: March 2022

Cellular membranes self-assemble from and interact with various molecular species. Each molecule locally shapes the lipid bilayer, the soft elastic core of cellular membranes. The dynamic architecture of intracellular membrane systems is based on elastic transformations and lateral redistribution of these elementary shapes, driven by chemical and curvature stress gradients. The minimization of the total elastic stress by such redistribution composes the most basic, primordial mechanism of membrane curvature-composition coupling (CCC). Although CCC is generally considered in the context of dynamic compositional heterogeneity of cellular membrane systems, in this article we discuss a broader involvement of CCC in controlling membrane deformations. We focus specifically on the mesoscale membrane transformations in open, reservoir-governed systems, such as membrane budding, tubulation, and the emergence of highly curved sites of membrane fusion and fission. We reveal that the reshuffling of molecular shapes constitutes an independent deformation mode with complex rheological properties.This mode controls effective elasticity of local deformations as well as stationary elastic stress, thus emerging as a major regulator of intracellular membrane remodeling.
An Overview for the Design of Antimicrobial Polymers: From Standard Antibiotic-Release Systems to Topographical and Smart Materials
Authors: Palza Humberto , Barraza Belén , Olate-Moya Felipe
Published: March 2022

Microorganisms attach on all kinds of surfaces, spreading pathogens that affect human health and alter the properties of products and of the surface itself. These issues motivated the design of a broad set of antimicrobial polymers that have great versatility to be chemically modified, processed, and mixed with other compounds. This review presents an overview of these different strategies, including antimicrobial-release systems and inherently antimicrobial polymers, alongside novel approaches such as smart materials and topographical effects. These polymers can be used in any application affected by microbes, from biomaterials and coatings to food packaging.
Perioperative assessment of muscle inflammation susceptibility in patients with end-stage osteoarthritis
Authors: Drummer Devin J. , McAdam Jeremy S. , Seay Regina , Aban Inmaculada , Lavin Kaleen M. , Wiggins Derek , Touliatos Gabriel , Yang Sufen , Kelley Christian , Tuggle S. Craig , Peoples Brandon , Siegel Herrick , Ghanem Elie , Singh Jasvinder A. , Schutzler Scott , Barnes C. Lowry , Ferrando Arny A. , Bridges S. Louis , Bamman Marcas M.
Published: March 2022

This study assessed the skeletal muscle molecular characteristics associated with end-stage osteoarthritis and refined an important phenotype, in some patients, termed muscle inflammation susceptibility (MuIS+) that may be an important consideration following surgery. Furthermore, we provide evidence of differential inflammatory and catabolic gene expression between the contralateral and surgical limbs along with differences between the skeletal muscle surrounding the diseased hip versus knee joints.
Effect of extracellular hyperosmolality during normothermia and hyperthermia on the autophagic response in peripheral blood mononuclear cells from young men
Authors: McCormick James J. , King Kelli E. , Rutherford Maura M. , Meade Robert D. , Notley Sean R. , Akerman Ashley P. , Dokladny Karol , Kenny Glen P.
Published: March 2022

We demonstrate that a physiologically relevant increase in serum osmolality causes minimal activation of the autophagic response. However, the combined stressors of serum hyperosmolality and mild hyperthermia causes activation of both autophagy and apoptotic signaling. Thus changes in osmotic homeostasis appear to influence the cell’s cytoprotective ability during periods of heat stress, highlighting the importance of considering osmotic status when examining autophagic responses in vivo.
Pricing Strategy of Electric Power Data Credit Product Based on Customer Value
Authors: Wang Zhimin , Wang Di
Published: March 2022

With the improvement of the intelligence level of the power network and the gradual improvement of the information and communication of the power system, the application of power big data to the corporate credit market is not only an important supplement to the national social credit system but also an important strategic goal for the State Grid to expand profitability. This paper constructs a benefit evaluation model for power data credit investigation products based on the utility of the products that financial institutions experience when they purchase and use financial risk control products. Based on the theory of customer value, comprehensively considering the characteristics of power credit reporting products, and taking profit maximization as the corporate goal, the pricing of a single power credit reporting product is studied, and the method is verified using example products. This article gives the pricing strategy of power credit investigation, which can be used as a reference for enterprises to further develop market strategies.
Analysis of Microstructure and Low Permeability with 3D Digital Rock Modeling
Authors: Wu Jinsui , Xing Min , Yin Shangxian , Zhang Ciyuan , Chen Xuexi , Yi Sihai , Lian Huiqing , Xie Dongyu
Published: March 2022

The sandstone microstructure and permeability are important parameters for quantitative evaluation of groundwater/oil/gas resources and prediction of flow rates of water/oil/gas. In this study, we applied seven low-permeability sandstone samples obtained from North China to research the microstructure and permeability based on digital core technology. Rock images were collected by X-ray microcomputed tomography (μCT), and then software (Avizo) was applied to analyze the microstructure and calculate the parameters such as porosity, connected porosity, average equivalent diameter, tortuosity, and shape factor. By introducing the shape factor into the Kozeny–Carman equation, we modified the Kozeny–Carman equation and found that the modified equation is a function of porosity, diameter of particles, tortuosity, and particle shape factor.
MRI Images Based on Semiautomatic Segmentation Algorithm for Prediction of Histological Grade of Breast Tumor
Authors: Wang Jiyuan , Zhou Yanling , Sun Shaokun , Xu Wenqian , Zou Hanqing
Published: March 2022

This study aimed to explore the effects of delayed enhanced magnetic resonance imaging (MRI) (DE-MRI) image features based on the semiautomatic circle-dependent (SCD)-based multiphase level set (MLS) (SCD-MLS) algorithm in predicting the histological grade of breast tumors. We explore the clinical effect of DE-MRI on the prediction of the histological grade of breast tumors (BTs). In this study, 264 breast tumor (BT) patients from The Second Affiliated Hospital of Soochow University were selected as the research objects, and DE-MRI examinations were performed. The SCD-MLS algorithm was compared with the Live-Wire algorithm for the segmentation effect and was applied to the DE-MRI image for prediction of the histological grade of BT. The results proved that the SCD-MLS algorithm in this study showed a more accurate segmentation effect with good stability. BT tissue showed a patchy low signal on T1WI and a high signal on T2WI. The number of patients with grade II was the highest (P < 0.05); the lesion diameters of grade II and grade III were concentrated at 1.5–2.5 cm and 2.5–3.5 cm, respectively (P < 0.05); the fractional anisotropy (FA) of patients with grade I was the largest (P < 0.05); and the apparent diffusion coefficient (ADC) of the patients with grade III was the highest (P < 0.05). In short, DE-MRI showed a good performance in the BT diagnosis, and the grading of BT tissue was related to lesion size, number of lesions, ADC, and FA.
Some New Aspects in the Intuitionistic Fuzzy and Neutrosophic Fixed Point Theory
Authors: Hussain Aftab , Al Sulami Hamed , Ishtiaq Umar
Published: March 2022

In this manuscript, we use the concepts of continuous t-norms and continuous t-conorms to introduce some definitions, in which intuitionistic fuzzy rectangular metric spaces, intuitionistic fuzzy rectangular metric-like spaces, intuitionistic fuzzy rectangular b-metric spaces, intuitionistic fuzzy rectangular b-metric-like spaces, neutrosophic rectangular metric spaces, neutrosophic rectangular metric-like spaces, neutrosophic rectangular b-metric spaces, and neutrosophic rectangular b-metric-like spaces are included. Continuous t-norms and continuous t-conorms are used to generalize the probability distribution of triangular inequalities in metric space axioms. Nontrivial examples, some fixed point results, and an application to the integral equation are imparted in this manuscript.
Cyclic Polypeptide D7 Protects Bone Marrow Mesenchymal Cells and Promotes Chondrogenesis during Osteonecrosis of the Femoral Head via Growth Differentiation Factor 15-Mediated Redox Signaling
Authors: Chen Jiazheng , Cui Zichen , Wang Yi , Lyu Linmao , Feng Changgong , Feng Dianjie , Cheng Yifan , Li Ziqing , Sun Shui
Published: March 2022

Osteonecrosis of the femoral head (ONFH) is a debilitating disease that is closely associated with the clinical application of high-dose glucocorticoids. Elevated oxidative stress contributes to the pathophysiological changes observed in ONFH. The lack of effective treatments besides surgical intervention highlights the importance of finding novel therapeutics. Our previous studies demonstrated that D7, a cyclic polypeptide, enhances the adhesion, expansion, and proliferation of bone marrow mesenchymal stem cells (BMSCs). Therefore, in this study, we investigated the therapeutic effects of D7 against ONFH in BMSCs and evaluated the underlying mechanisms. First, we screened for ONFH risk factors. Then, we applied D7 treatment to steroid-induced ONFH (SONFH) in an in vitro model produced by dexamethasone (DEX) to further elucidate the underlying mechanisms. We found negative correlations among oxidative stress marker expression, growth differentiation factor 15 (GDF15) levels, and ONFH. Furthermore, we demonstrated that DEX inhibited the proliferation and induced apoptosis of BMSCs by suppressing GDF15/AKT/mammalian target of rapamycin (mTOR) signaling. D7 alleviated DEX-induced BMSCs injury and restored the chondrogenic function of BMSCs by activating GDF15/AKT/mTOR signaling. In addition, DEX-induced excessive reactive oxygen species (ROS) generation was an upstream trigger of GDF15-mediated signaling, and D7 ameliorated this DEX-induced redox imbalance by restoring the expression of antioxidants, including superoxide dismutase (SOD) 1, SOD2, and catalase, via regulation of GDF15 expression. In conclusion, our findings revealed the potential therapeutic effects of D7 in SONFH and showed that this protective function may be mediated via inhibition of DEX-induced ROS and activation of GDF15/AKT/mTOR signaling, thereby providing insights into the potential applications of D7 in SONFH treatment.
[Retracted] A Study on the Relationship between Mental Resilience, Work‐Family Conflict, and Anxiety of Nurses in Shandong, China
Authors: Qi Qin , Yan Xiaoyun , Gao Meng , Wu Xia , Zhang Shuhong , Dela Rosa Ronnell D. , Zhang Yan , Xu Yuzhen
Published: March 2022

Based on Freud’s personality theory, 839 nurses from 5 public hospitals in Shandong Province were selected by the convenience sampling method. A cross‐sectional survey was conducted to investigate the correlation among resilience, work‐family conflict (WFC), and anxiety (SAS). The purpose of this study was to explore the relationship among resilience, WFC, and SAS of these nurses and to provide evidence with reducing WFC and SAS for the nurses. The results showed that the total score of resilience, WFC, and SAS was 58.00 ± 18.27, 53.46 ± 13.29, and 49.98 ± 14.73, respectively. There was 47.68% of the nurses that had anxiety, and 10.97% of the nurses had severe anxiety. There were significant differences in the score of SAS among the length of service, self‐perceived health status, confidence in nursing professional development, WFC, and resilience (P < 0.05). This study draws the following conclusions: the proportion of anxiety is high, and the level of resilience is lower than the domestic norm. Length of service, self‐perceived health status, confidence in nursing professional development, WFC, and resilience were the important influencing factors of anxiety. It is suggested that hospital managers should pay attention to the mental health of nurses, take active intervention measures according to the influencing factors of SAS, improve nurses’ psychological resilience, reduce WFC and anxiety, improve nurses’ mental health and well‐being, and ensure nursing safety.
Analysis of the Performance Characteristics of ZnO Nanoparticles’ Dispersed Polyester Oil
Authors: Kumar V. P. Suresh , Manikandan N. , Nagaprasad N. , LetaTesfaye Jule , Krishnaraj Ramasamy
Published: March 2022

Analysis of performance characteristics of nanoparticles’ dispersed oil has wide and an important role in oil industries. Zinc oxide nanoparticles are dispersed with polyester oil by using an ultrasonic vibrator and magnetic stirrer. Nanoparticles’ concentration are taken as 0.1, 0.3, and 0.5 wt. %. The ball-milling process is used to reduce the size of the nanoparticles before the preparation of nanoparticles’ dispersed polyester oil (NPDP). Spherical shape particles with an average size of 40 nm are achieved for unmilled nanoparticles, whereas spherical shape particles with an average size of 30 nm are achieved for ball-milled nanoparticles. Pin on disc analysis shows the coefficient of friction of unmilled and ball-milled NPDP. Ball-milled NPDP results in a lesser coefficient of friction. Thermal conductivity of unmilled and ball-milled NPDP is finalized through the transient hot-wire method. Ball-milled NPDP enhances the thermal conductivity of base polyester oil than the usage of unmilled NPDP in polyester oil. In this study, the assessment and optimization of nanoparticle concentration, temperature, and ball-milling processes of nanoparticles are also carried out using the design of experiment (Doe) approach. The L9 orthogonal array-based full factorial design is used for the best optimization result. The response tables with graphs and optimal results have been obtained through the Taguchi method.
Attention Analysis and Information Dissemination Effect of Young People Based on Multisource Sensors under the Background of Wireless Communication and Artificial Intelligence
Authors: Liu Zheng , Li Rong
Published: March 2022

In recent years, the development of wireless communication and artificial intelligence technology has brought tremendous convenience to human life. Especially in the fields of education and medical treatment, the functions of wireless communication are the most representative. In order to enhance the attention of young people and the effect of information dissemination, scholars have conducted many analyses on its influencing factors. Studies have found that strong noise environments have obvious negative effects on attention and information dissemination effects. Therefore, this paper proposes a multisource sensor-based method for young people’s attention analysis and information dissemination effect enhancement in a strong noise environment. Multisource sensors are selected to perform young people’s attention analysis on speech in a strong noise environment, combined with the information dissemination effect to strengthen the model obtained by combining attention analysis and information dissemination effect strengthened speech. Through the multisource sensor system, it is demonstrated that the method in this paper is superior to the traditional method in a strong noise environment. And through the comparative analysis of multisource sensors, the corresponding improvement plan for the strong noise environment was formulated, and the numerical simulation experiment of young people's attention analysis and information dissemination effect was carried out to verify the optimization results. This research, based on wireless communication and artificial intelligence decision-making technology, proposes to evaluate and optimize the attention analysis and information dissemination effect of young people in a strong noisy environment based on multisource sensors and gives useful ideas to ensure the system design method in a strong noisy environment and the environmental quality after implementation. It also provides support and help for people to more specifically prevent the adverse effects on people’s attention analysis and information dissemination effects in a strong noise environment. This paper designs a model based on multisource sensors to study the effect of young people's attention analysis and information dissemination in a strong noise environment, which is of great significance to the development of people’s high-quality life.
Experimental Study on the Oil Recovery Performance of CO2 Huff-and-Puff Process in Fractured Tight Oil Reservoirs
Authors: Qian Kun , Huang Yu , He Yanfeng , Dou Xiangji , Wu Xiaojun
Published: March 2022

In order to investigate energy supply capacity and oil production contribution of near-fracture and fracture-free zone in fractured tight oil reservoirs, a series of CO2 huff-and-puff tests were designed and carried out in different experimental conditions. A fracture-matrix long-core system was established to simulate the near-fracture zone and matrix zone of tight oil reservoirs. The NMR technique was utilized to identify the microscopic remaining oil of certain core samples. The effects of fracture length, soaking time, depressurization method, and asphaltene precipitation on the oil recovery performance of CO2 huff-and-puff process were evaluated, respectively. The results indicated that the dissolution and diffusion range of the injected CO2 can be apparently increased from both macro and micro aspects through increasing the length or density of the fractures and extending the soaking time; and, during puff period, the slow depressurization method has better recovery effect on near-fracture zone, while the step depressurization method has better recovery effect on distal fracture-free matrix. After CO2 huff-and-puff process, the oil recovery of the medium pores near fracture could be close to oil recovery of the large pores, which is higher than 60%. But, in the distal matrix, the oil recovery of the medium pores was only a little higher than depletion development. The remaining oil of medium pores in distal fracture-free matrix still has great potential to be developed after CO2 huff-and-puff process.
Social Media Big Data Analysis: Towards Enhancing Competitiveness of Firms in a Post-Pandemic World
Authors: Darwiesh Abdelaziz , Alghamdi Mohammed. I , El-Baz A. H. , Elhoseny Mohamed
Published: March 2022

In this paper, we proposed an advanced business intelligence framework for firms in a post-pandemic phase to increase their performance and productivity. The proposed framework utilizes some of the most significant tools in this era, such as social media and big data analysis for business intelligence systems. In addition, we survey the most outstanding related papers to this study. Open challenges based on this framework are described as well, and a proposed methodology to minimize these challenges is given. Finally, the conclusion and further research points that are worth studying are discussed.
Pressure Law of Roof and Supporting Technology of Roadway When Working Face Passing through Abandoned Roadway
Authors: Pan Weidong , Deng Cang , Yang Yinchao , Zhang Kunming , Gao Shan
Published: March 2022

Unlike conventional long-wall mining, the roofing activity is more intense when the long-wall face passes through the abandoned roadway. Technically, the coal pillar between the abandoned roadway and the long-wall face will suddenly fail with a certain critical value of its width, leading to the roof breaks in advance and other production-restricted problems because of the support loss, which will be a great threat to underground mining activities. In order to guarantee safe mining conditions, it is a great necessity to uncover how the roof breaks in advance and how to deal with it. From the stability maintaining of the key block perspective, this study looked at research from the 12404–1 long-wall face of Wulanmulun coal mine, China. The critical value of the coal pillar’s width was determined to be about 4.75 m by theoretical analysis, and likely, the appropriate supporting force of the abandoned roadway’s roof is about 1073 kN per meter. In this study, a numerical simulation method was adopted to study the ground pressure when the long-wall face is passing through the abandoned roadway. Correspondingly, a compound supporting technology involving the roof presplit technique, anchor cable supporting, and pumping pillar supporting was proposed for the roof of the abandoned roadway, and it practically worked well.
Chinese Language Literature Emotion Analysis Model Based on Unbalanced K-Nearest Neighbor Classification Method
Authors: Ji Jiaying
Published: March 2022

The Chinese language is a nation’s symbol, the accumulation of a country’s magnificent culture, and the pearl precipitated in the long history’s washing. The Chinese language is rich and complex, and there are still many topics and issues that merit repeated exchanges and discussions in academic circles. This study proposes a classification method of emotion polarity based on reliability analysis in order to identify the tendency of literary emotion in Chinese language. Support vector machine (SVM), class center, and KNN (K-nearest neighbor) are included in the combined classifier, which effectively improves the accuracy and efficiency of emotion polarity classification. A Chinese literary emotion analysis model based on the method of UKNNC (unbalanced K-nearest neighbor classification) is proposed at the same time by analysing the characteristics of text structure and emotion expression. The experimental results show that, when compared to traditional machine methods, the UKNNC method can analyse text sentiment in fine-grained and multilevel ways, while also improving the accuracy of Chinese literary sentiment analysis.
The Therapeutic Potential of Aprepitant in Glioblastoma Cancer Cells through Redox Modification
Authors: Rezaei Soodabeh , Assaran Darban Reza , Javid Hossein , Hashemy Seyed Isaac
Published: March 2022

Although there is no doubt regarding the involvement of oxidative stress in the development of glioblastoma, many questions remained unanswered about signaling cascades that regulate the redox status. Given the importance of the substance P (SP)/neurokinin 1 receptor (NK1R) system in different cancers, it was of particular interest to evaluate whether the stimulation of this cascade in glioblastoma‐derived U87 cells is associated with the induction of oxidative stress. Our results showed that SP‐mediated activation of NK1R not only increased the intracellular levels of malondialdehyde (MDA) and reactive oxygen species (ROS) but also reduced the concentration of thiol in U87 cells. We also found that upon SP addition, there was a significant reduction in the cells’ total antioxidant capacity (TAC), revealing that the SP/NK1R axis may be involved in the regulation of oxidative stress in glioblastoma cells. The significant role of SP/NK1R in triggering oxidative stress in glioblastoma has become more evident when we found that the abrogation of the axis using aprepitant reduced cell survival, probably through exerting antioxidant effects. The results showed that both MDA and ROS concentrations were significantly reduced in the presence of aprepitant, and the number of antioxidant components of the redox system increased. Overall, these findings suggest that aprepitant might exert its anticancer effect on U87 cells through shifting the balance of oxidant and antioxidant components of the redox system.
Semiconducting Carbon Nanotube-Based Nanodevices for Monitoring the Effects of Chlorphenamine on the Activities of Intracellular Ca2+ Stores
Authors: Pham Ba Viet Anh , Pham Van Bach Ngoc , Nguyen Luong Thien , Nguyen Khoa Viet
Published: March 2022

We report a flexible and noninvasive method based on field-effect transistors hybridizing semiconducting single-walled carbon nanotubes for monitoring the effects of histamine on Ca2+ release from the intracellular stores of a nonexcitable cell. These nanodevices allowed us to evaluate the real-time electrophysiological activities of HeLa cells under the stimulation of histamine via the recording of the conductance changes of the devices. These changes resulted from the binding of histamine to its receptor type 1 on the HeLa cell membrane. Moreover, the effects of chlorphenamine, an antihistamine, on the electrophysiological activities of a single HeLa cell were also evaluated, indicating that the pretreatment of the cell with chlorpheniramine decreased intracellular Ca2+ release. Significantly, we only utilized a single nanodevice to perform the measurements for multiple cells pretreated with various concentrations of chlorphenamine. This enabled the statistically meaningful analysis of drug effects on cells without errors from device variations. Obtained results indicated the novel advantages of our method such as real-time monitoring and quantitative capability. Our devices, therefore, can be efficient tools for biomedical applications such as electrophysiology research and drug screening.
The Experimental Investigation of the Optimization of the Flow State of a Ladder-Shaped Spillway in a Certain Reservoir
Authors: Gu Xin-Bao , Zhang Yang , Wu Qi-Hong , Wang Yong
Published: March 2022

The original design scheme of ladder-shaped spillways in certain reservoirs is improved by using a hydraulic similar model experiment. The results of the original scheme demonstrate that the stilling basin cannot meet the requirement of safe discharge, and the flow state at the end of the stilling basin is violent and chaotic. The experimental method of the physical model was used to optimize the design of the spillway without changing the original plane layout. First, three steps in the ladder are added. The stilling basin is then replaced by the torsion plane. Finally, the longitudinal slope of the tail channel section is altered, and an experimental investigation on the flow state and energy dissipation rate is performed. The conclusions are drawn that the flow state of the water is obviously improved, and the energy dissipation rate increases; the optimal scheme produces the expected effects.
Very Early Severe Posttransplant Recurrent Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis after Kidney Transplantation: Two Case Reports
Authors: Laamech Reda , Naciri-Bennani Hamza , Giovannini Diane , Noble Johan , Janbon Bénédicte , Malvezzi Paolo , Jouve Thomas , Rostaing Lionel
Published: March 2022

Successful kidney transplantation (KTx) in patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV) has been reported with excellent patient and graft survival rates. The recurrence of AAV in transplant recipients is rare, and its mechanisms of action are not clearly known. The optimum time for KTx and the relevance of ANCA titer at the time of transplantation remain controversial. We report two cases of extremely rapid recurrent AAV after renal transplantation; both were still ANCA-positive at the time of transplantation, which led us to question the pathogenesis of ANCA antibodies in recurrence in a kidney allograft. Apheresis plus immunosuppressive therapies were ineffective in the first case and the patient became dialysis-dependent, whereas in the second case methylprednisone pulses plus rituximab infusions resulted in long-lasting remission.
Advanced Glycation End Products Induced Mitochondrial Dysfunction of Chondrocytes through Repression of AMPKα-SIRT1-PGC-1α Pathway
Authors: Yang Qingshan , Shi Yucong , Jin Tao , Duan Bowen , Wu Shujin
Published: March 2022

Introduction: Our previous studies have demonstrated advanced glycation end products (AGEs) was an important mediator in osteoarthritis (OA) which may induce mitochondrial dysfunction. AMP-activated protein kinase (AMPK), sirtuin 1 (SIRT1), and its downstream target peroxisome proliferator-activated receptor gamma coactivator-1α (PGC-1α) are the critical sensors that regulate mitochondrial biogenesis and have been recognized as therapeutic targets in OA. This study was designed to test whether AGEs caused mitochondrial dysfunction through modulation of AMPKα/SIRT1/PGC-1α. Methods: We knocked down or overexpressed AMPKα, SIRT1, and PGC-1α by small interfering RNA or plasmid DNA transfection, respectively. Mitochondrial membrane potential (△Ψ) was detected by tetraethylbenzimidazolyl carbocyanine iodide (JC-1) fluorescence probe. Results: The results showed that AGEs impaired △Ψ, intracellular ATP level, and mitochondrial DNA content, linked to decreased AMPKα, SIRT1, and PGC-1α expression in chondrocyte. AMPKα pharmacologic activation or overexpression of AMPKα, SIRT1, and PGC-1α reversed impairments of mitochondrial biogenesis, oxidative stress, and inflammation in AGEs-induced chondrocytes. However, AMPKα activation using AICAR had decreased capacity to increase each of those same effect readouts in AGEs-treated SIRT1-siRNA or PGC-1α-siRNA chondrocyte. Conclusion: Taken together, AGEs reduced the AMPKα/SIRT1/PGC-1α signaling in chondrocytes, leading to mitochondrial dysfunction as a result of increased oxidative stress, inflammation, and apoptosis. These results indicated that target AMPK may be as a novel therapeutic strategy for AGEs-related OA prevention.
Correlation between Surgical Outcomes of Primary Hyperparathyroidism with Neck Ultrasound and Parathyroid Scan-Tc99m/MIBI Localization Studies in Dubai Hospital
Authors: Alemadi Budoor , Alsaeed Maryam Ahmad , Alsayyah Fatima , Rahma Salma , Al Awadi Fatheya , Rashid Fauzia
Published: March 2022

Objective: The aim of this study is to assess the correlation between the findings in preoperative localization studies and biochemical parameters with the surgical outcome in patients with primary hyperparathyroidism. Design and Methods: In patients with hyperparathyroidism, preoperative localization imaging studies are considered important for their role in surgical cure, operative length, and extent of surgical incision. Sometimes discordant imaging studies lead to further extensive diagnostic work-up to avoid operative risks and may result in delay to surgical referral. In this single-center retrospective study at a tertiary referral center in Dubai, we evaluated the concordance of presurgical imaging modalities in primary hyperparathyroidism with the surgical outcome after parathyroidectomy. Results: This study included n = 59 patients. 74.6% were female, and the mean age was 52.59 years (SD = 13.6). Preoperative parathyroid sestamibi scans were done on n = 50 patients with 68% having a positive result. A radiology department neck ultrasound was done on n = 42 patients, 52% of whom had a positive finding for a parathyroid adenoma, while n = 17 patients required an endocrinology department neck ultrasound scan with 71% having a positive finding. Complete concordance of findings with the postoperative pathology result was found in 78% of patients who had a preoperative parathyroid sestamibi, 78% of patients who had a preoperative radiology department neck ultrasound, and 86% of patients with a preoperative endocrinology department ultrasound. There was no correlation between the preoperative laboratory values of calcium and PTH with the scan findings based on our data. Conclusion: Our results showed a high degree of complete concordance between the usual imaging modalities and surgical findings.