bluuebunny/crossref_metadata_2025 huggingface dataset:
Pulmonary arterial hypertension screening of systemic sclerosis patients in clinical practice: an independent chart review
Authors: Kelly Dylan , Beattie Karen A. , Larché Maggie J.
Published: July 2017

Patients with systemic sclerosis (SSc) are at increased risk of pulmonary arterial hypertension (PAH). Guidelines recommend annual screening with pulmonary function testing (PFT) and transthoracic echocardiogram (TTE). Through auditing the charts of 11 rheumatologists associated with McMaster University, we evaluated the proportion of SSc patients without PAH or pulmonary fibrosis who receive annual TTE, PFT, and dyspnea screening. Screening rates between self-identified SSc experts and non-experts were compared. In cases where screening tests were abnormal, charts were reviewed for evidence of cardiologist or respirologist referral. In total, 136 patients’ charts were included. Annual screening for dyspnea was very common (88% of patients, 119/134). Annual PAH screening via TTE (74%, 100/135) and PFT (79%, 107/136) was less common. Annual dyspnea screening, TTE, and PFT were more commonly performed by SSc experts than by non-experts (94% vs. 83%, p = 0.03; 85% vs. 61%, p = 0.002; 93% vs. 62%, p<0.001, respectively). Nearly all patients with an abnormal TTE (10/11, 91%) and PFT (12/14, 86%) received appropriate referrals. Future research should explore reasons for differences in screening rates between SSc experts and non-experts. Given that rheumatologists screen for dyspnea more often than they order PFT and TTE, there may be barriers to ordering these tests that warrant further investigation.
Pathogenesis of systemic sclerosis: recent insights of molecular and cellular mechanisms and therapeutic opportunities
Authors: Varga John , Trojanowska Maria , Kuwana Masataka
Published: July 2017

Systemic sclerosis (SSc) is a complex disease characterized by early microvascular abnormalities, immune dysregulation and chronic inflammation, and subsequent fibrosis of the skin and internal organs. Excessive fibrosis, distinguishing hallmark of SSc, is the end result of a complex series of interlinked vascular injury and immune activation, and represents a maladaptive repair process. Activated vascular, epithelial, and immune cells generate pro-fibrotic cytokines, chemokines, growth factors, lipid mediators, autoantibodies, and reactive oxygen species. These paracrine and autocrine cues in turn induce activation, differentiation, and survival of mesenchymal cells, ensuing tissue fibrosis through increased collagen synthesis, matrix deposition, tissue rigidity and remodeling, and vascular rarefaction. This review features recent insights of the pathogenic process of SSc, highlighting three major characteristics of SSc, microvasculopathy, excessive fibrosis, and immune dysregulation, and sheds new light on the understanding of molecular and cellular mechanisms contributing to the pathogenesis of SSc and providing novel avenues for targeted therapies.
Factors Causing Loss of Normal Doppler Waveform of the Left Internal Jugular Vein: Evaluation on Chest Computed Tomography
Authors: Ku Min Cheol , Song Myung Gyu , Seo Tae-Seok , Kang Eun Young , Yong Hwan Seok , Lee Jae Wook
Published: July 2017

Purpose

To evaluate the presence and causes of left brachiocephalic vein (LBCV) steno-occlusive lesions in patients with loss of normal waveform in Doppler ultrasound of the left internal jugular vein (LIJV).

Materials and Methods

We performed Doppler ultrasound of both internal jugular veins in 1912 patients who received an implantable venous access port from August 2013 to January 2016. Among them, 106 patients showed loss of normal Doppler waveforms of the LIJV (56 men and 50 women; mean age, 61.4 ± 11.6 years). We retrospectively analyzed the presence and causes of the LBCV steno-occlusive lesions on contrast-enhanced chest computed tomography (CT) images.

Results

LBCV steno-occlusive lesions were present in 82 patients (77.4%). The causes of these lesions were anatomic structures (n = 70, 85.4%), tumorous lesions (n = 11, 13.4%), and thrombus (n = 1, 1.2%). The anterior anatomic structures to the LBCV causing stenosis were bony structures (n = 50), right upper lobe (n = 11), and mediastinal fat (n = 9). The posterior anatomic structures to the LBCV resulting in stenosis were right brachiocephalic artery (n = 58), left common carotid artery (n = 7), and aortic arch (n = 5). The tumorous lesions resulting in stenosis were mediastinal lymph node (n = 5), thymic lesions (n = 3), lymphoma (n = 1), lung cancer (n = 1), and bone tumor (n = 1).

Conclusions

It is necessary to suspect steno-occlusive lesion of the LBCV from various causes and to use caution when performing central venous catheterization in cases with loss of a normal Doppler waveform.
Lancisi’s sign and central venous catheter tip position: a case report
Authors: Vigo Valentina , Lisi Piero , Galgano Giuseppe , Lomonte Carlo
Published: July 2017

Introduction:

Valvular disease and pulmonary hypertension are common conditions in haemodialysis patients. In presence of tricuspid regurgitation, an increased retrograde blood flow into the right atrium during ventricle systole results in a typical modification of the normal venous waveform, creating a giant c-v wave. This condition clinically appears as a venous palpable pulsation within the internal jugular vein, also known as Lancisi’s sign.

Case report:

An 83-year-old woman underwent haemodialysis for 9 years. After arteriovenous fistula thrombosis, a right internal jugular vein non-tunnelled central venous catheter (CVC) was placed. About one month later, the patient was referred to our facility for the placement of a tunnelled CVC. Neck examination revealed an elevated jugular venous pulse, the Lancisi’s sign. Surprisingly, chest x-ray posteroanterior view showed the non-tunnelled catheter tip in correspondence with the right ventricle. She underwent surgery for temporary to tunnelled CVC conversion using the same venous insertion site (Bellcath®10Fr-length 25 cm to Mahurkar®13.5Fr-length 19 cm). In the postoperative period, we observed a significant reduction of the jugular venous pulse.

Discussion:

The inappropriate placement of a 25-cm temporary CVC in the right internal jugular vein worsened the tricuspid valve regurgitation, which became evident by the Lancisi’s sign. Removal of the temporary CVC from the right ventricle resulted in improved right cardiac function. Safe approaches recommended by guidelines for the CVC insertion technique and for checking the tip position should be applied in order to avoid complications.
Sexual Health, Adherence to Mediterranean Diet, Body Weight, Physical Activity and Mental State: Factors Correlated to Each Other
Authors: Della Camera Pier A. , Morselli Simone , Cito Gianmartin , Tasso Giovanni , Cocci Andrea , Laruccia Nicola , Travaglini Fabrizio , Del Fabbro Dario , Mottola Antonio R. , Gacci Mauro , Serni Sergio , Carini Marco , Natali Alessandro
Published: July 2017

Introduction

Mediterranean diet has shown a protective role against cardiovascular disease, diabetes, cancer onset, microvascular damage and dementia in many trials. Our purpose is the assessment of a correlation between physical activity, Mediterranean diet, body mass index (BMI), depression and erection disorder (ED).

Methods

After having signed disclaimer to the study participation, we administered the IIEF 15 questionnaire (International Index of Erectil Function), the Hamilton questionnaire for major depression, the Med-Diet Questionnaire, the Ipaq Questionnaire (International Index of Physical Activity) to 245 patients and calculated the BMI. Only 141 were eligible. We excluded patients with a history of smoking, with obesity from the second grade to rise, anorexia, hyperlipidemia, Induratio Penis Plastica, diabetes, cardiovascular and neurological disease, hypogonadism, prostatitis, diabetes, hypertension, psychiatric diseases and the history of radical prostatectomy and finally age >72 and <50 years or who were taking cholesterol-lowering medication. Patients were divided into two groups: 65 patients without ED and 76 patients with ED.

Results

We found a statistically difference in BMI between the groups. Adherence to Med-Diet showed a significant difference between the two groups at Student t-test and the Chi-square test. The Ipaq test and Hamilton test did not show statistical differences between the two groups neither for Student t-test nor for Chi-square test, but high levels seem to be protective factors.

Conclusions

Body weight and a healthy diet are protective factors against the ED, more than a sufficient physical activity. Depression has shown only a worsening tendency of the erection.
The Determinants of Stock Returns in the Emerging Market of Kenya: An Empirical Evidence
Authors: Mumo Muinde Patrick
Published: July 2017

This study examined the sources of risk factors that determine stock returns in the emerging market of Kenya. The specific objectives were to determine the validity of the Capital Asset Pricing Model (CAPM) and then empirically test for factors that are priced in stock returns in Kenya.The factors examined are the excess market premium and selected macroeconomic factors including inflation, exchange rates, money supply and short term interest rates. The study utilizes monthly time series data for the period April 1996: December 2016. The CAPM, a multifactor approach and Fama and MacBeth (1973) two-step procedure are used for data analysis.The study finds that CAPM cannot be rejected and that the market premium is the most important factor in explaining stock return variability in Kenya. Therefore, the study concludes that unlike the recent evidence on the collapse of CAPM in advanced markets, the model can still be validly used for the Kenyan market.
Discursive Strategies and Politics of (Neo-)colonialism: A Textual Analysis of Saadat Hassan Manto’s Letters to Uncle Sam
Authors: Ullah Inayat , Aib Iman
Published: July 2017

Colonialism has been such a multifaceted and complicated phenomenon that it often juxtaposed the culture of the colonized in simultaneous assimilation of, and resistance to, the culture of the colonizers. Embedded in the theory of Post colonialism, this research aims at carrying out a qualitative analysis of discursive strategies used in Saadat Hassan Manto’s literary work Letters to Uncle Sam from a neo-colonial perspective. It seeks to highlight the issues of globalization and the effects that it engendered upon the then newly-established independent state of Pakistan. The research findings conclude that globalization has resulted in putting an end to the so-called purity of culture. Manto, therefore, explicitly satirizes the super power (read the United States of America) for its hidden agendas of manipulating and exploiting the economic system as well as the cultural beliefs of Pakistan under the mask of prospering nations by building a global market to create a new means of dominance that works through consent.
A Study of Architecture of Thin Interlayer within Meandering River Monosandbody of Thick-Bedded Oil Layers
Authors: Shan Jingfu , Lin Zhipeng , Chen Le , Liu Bo , Fang Wei , Zhang Le , Xie Lili
Published: July 2017

This paper investigates the reservoir architecture of thin interlayer within meandering river monosandbody in the thick-bedded oil layers. The thin interlayer within the monosandbody of the terrestrial reservoir is one of the dominant factors which form the reservoir heterogeneity of fluid motion. It is of equal importance in comparison with the rhythmic distribution of permeability, and it is also the important content of the elaborate representation of reservoirs. However, previous researches of the heterogeneity of reservoir focus mostly on the theory of distribution disparity of the permeability and neglect the influence of thin interlayer on the heterogeneity. Therefore, taking the PⅠ2 individual reservoir at the Putaohua reservoir formation in Daqing oilfield as an example, this paper analyzes the distribution, formation, and the three-dimensional construction of the internal thin interlayer of the monosandbody from a new point of view, on the basis of which a set of cycle research technique about it is put forward. With the method of configuration parameter extraction, which is most important before establishing interlayer configuration in three dimensions, this study clarifies the classification, causes of formation and the differences of distinct monosandbodies. Ultimately, four categories of thin interlayer according to the characteristics of the studied area is divided and two dominate causes for thin interlayer formation is discussed: argillaceous and arenaceous rock interlayer through deposition and interlayer in process of sedimentary diagenesis.For the convenience of the study, here mainly focuses on the thick - thin interlayer. Techniques are taken the use of determining the obliquity of the thin interlayer superface based on the configuration of paired wells and abandoned channel surface. The causes for thin interlayer and their classification, distribution and the three-dimensional construction are entirely revealed, which would possess important geologic meaning for taking affective engineering measures in the aspects of the elaborate representation of oil reservoir, and the research of remaining oil formation and distribution.
Minimum Principle-Type Necessary Optimality Conditions in Scalar and Vector Optimization. An Account
Authors: Giorgi Giorgio
Published: July 2017

We take into condideration necessary optimality conditions of minimum principle-type, that is for optimization problems having, besides the usual inequality and/or equality constraints, a set constraint. The first part pf the paper is concerned with scalar optimization problems; the second part of the paper deals with vector optimization problems.
Polar Particle Swarm Algorithm for Solving Cloud Data Migration Optimization Problem
Authors: Al-Sayyed Rizik M. H. , Fakhouri Hussam N. , Rodan Ali , Pattinson Colin
Published: July 2017

Particle Swarm Optimization (PSO) has proved to be a common meta-heuristic algorithm for determining the minimum value among a set of values but it is known to suffer from the local minima problem. In this paper, we propose a novel optimization algorithm called POLARPSO that enhances the behavior of PSO and avoids the local minima problem by using a polar function to search for more points in the search space. The algorithm has been tested on 23 well-known benchmark factions and the results are verified by comparing them with state of the art algorithms: Grey Wolf Optimizer (GWO), Sine Cosine Algorithm (SCA), Multi-Verse Optimizer (MVO) as well as PSO. The paper also considers a solution to the cloud data migration problem where data migrates from highly loaded nodes to less loaded nodes in a process aims at achieving a kind of load balancing. The results prove that the proposed algorithm is applicable to solve this challenging problem in cloud environment and is able to find the best node to migrate to quickly and effectively. Our empirical results show that the proposed algorithm has enhanced the PSO behavior in reaching the best solution and outperformed the other algorithms over the tested benchmarked functions.
Modeling Study on Stiffness Characteristics of Hydraulic Cylinder under Multi-Factors
Authors: Feng Hao , Du Qungui , Huang Yuxian , Chi Yongbin
Published: July 2017

For a complex mechanical system driven by hydraulic cylinders, the dynamic response characteristics of the mechanical system are significantly affected by the stiffness characteristics of hydraulic cylinders. This paper comprehensively studies the impacts of various factors on the stiffness characteristics of the hydraulic cylinders, including the oil bulk modulus, the air content in the hydraulic oil, the axial deformation of the piston rod, the volume expansion of the cylinder barrel, the volume expansion of the metal pipes and the flexible hoses, and the deformation of the hydraulic cylinder sealing. By combining the theoretical analysis and the experimental results, the level of each impacting factor was quantified, and the stiffness model of the hydraulic cylinder was established. Finally, comparative analysis of the stiffness was conducted by taking the experimental hydraulic cylinder as an example; it was verified that the calculated results of the proposed hydraulic cylinder stiffness model approximated the experimental results. Compared with stiffness models presented in current literature, the average accuracy was improved by more than 15 %.
Development of a Servo-Based Broaching Machine Using Virtual Prototyping Technology
Authors: Park Seok Hong , Dang Duc Viet , Nguyen Trung Thanh
Published: July 2017

Predicting machine tool performance at the design stage is one way to resolve the time issue and achieve cost savings. The objective of this paper was to develop a new non-hydraulic broaching machine using a servo motor, ball screw, and roll element linear guide using virtual prototyping technology. First, we developed a multi-body simulation model (MBS) of a servo-based broaching machine to investigate its dynamic behaviour. Then, an adaptive sliding mode proportional-integral-derivative (PID)-based controller (ASMPID) was proposed to conduct the broaching process. We then performed a co-simulation between the mechanical structure and virtual controller to investigate the ram body trajectory and identify the optimal control parameters. Finally, we manufactured a prototype machine to evaluate the simulation results and determine the benefits of the new system. Our results indicated that the proposed model, which includes a mechanical structure and intelligent controller, effectively improved broaching machine design. Therefore, this work is expected to improve the prototyping efficiency of new broaching machines.
La cotidianeidad y sus redes temáticas en la poesía de Lucía Muñoz Maceo
Authors: Álvarez Amargós Michelle María , Parra Noguera Virginia , Mariño Medina Martha María
Published: July 2017

La creación lírica femenina en Cuba resulta un proceso continuo marcado por rupturas y regularidades formales y conceptuales que posibilitan la estructuración de una identidad espiritual, visible no solo en la comunidad entre generaciones y movimientos, sino en la sistematicidad y evolución de las temáticas que ocupan a las escritoras. Este ensayo propone un acercamiento a las redes temáticas que tejen la cotidianeidad en tres poemarios de Lucía Muñoz Maceo para establecer asociaciones con la tradición poética. Además de las influencias de otras escritoras, se reconocen en su poesía los vínculos de la cotidianeidad con el amor, la familia, la búsqueda existencial y la patria.
Cuánta destrucción en los nidos americanos / cuántas patrias arruinadas y marchitas: poéticas de infancia en el Chile del siglo XXI
Authors: Hernández Biviana , Simon Salinas Francisco
Published: July 2017

El siguiente trabajo tiene como objetivo analizar un corpus de obras poéticas publicadas en Chile durante la primera década del siglo XXI, a partir de las distintas simbolizaciones que ellas plantean en torno a dos figuras culturales que resultan claves para entender el imaginario de la letra poética actual en nuestro país. Nos referimos a la casa y el niño, ambas como metáforas de una habitabilidad fracasada e, incluso, imposible, que se produce como efecto de la economía neoliberal, consolidada en el campo cultural chileno tras el retorno a la democracia.
Lírica y poéticas no-representacionales: dos poetas "peruanos"
Authors: Padilla Bustillos José Ignacio
Published: July 2017

Este ensayo explora formas de subjetividad emergentes partiendo de la hipótesis de que éstas se manifiestan de manera anticipada y no del todo articulada en la poesía y en el arte. Vivimos en un momento post-identitario y la lírica se reinventa ante esta exigencia histórica. Los dos poetas estudiados, Rafael Espinosa y Emilio Lafferranderie, ponen en marcha prácticas que superan los usos habituales del discurso poético (identificación, subrogación del yo). Su modo de resistencia consiste en bloquear o dificultar los procesos de identificación que propone el mercado cultural como compensación simbólica al bloqueo de la vida política.
El testimonio del momento inasible. Remembranza y transfiguración de la tradición poética china en Irás y no volverás de José Emilio Pacheco (1973)
Authors: Cervera Salinas Vicente
Published: July 2017

La poesía hispanoamericana, y más concretamente la mexicana, entra brillantemente en la década de los años setenta con un poemario central en la trayectoria lírica de José Emilio Pacheco, Irás y no volverás. Si bien fue publicado en edición príncipe por Fondo de Cultura Económica en 1973, los textos que lo integran abarcan un lapso temporal de composición desde 1969 hasta 1972, según indicación expresa del propio autor. Como bien sabemos, Pacheco gustó de publicar sus poemas en ediciones completas que, bajo el título de Tarde o temprano (editado por primera vez en 1980), iban ampliando su índice con los subsiguientes poemarios que el autor presentaba de manera independiente. En estas colecciones (la de 1980, la de 2000, ambas mexicanas) y la española de 2010 (que reproduce la mexicana de Era, de 2009) Pacheco introducía siempre, en su afán por precisar cuestiones relativas al tiempo y sus mutaciones, las fechas no sólo de las ediciones primeras de sus poemarios, sino las relativas al arco  temporal de escritura o redacción que abarcaba cada uno de ellos.
Las entrevisiones de Fina García Marruz: a propósito del poemario Viaje a Nicaragua (1987)
Authors: Rodríguez Gutiérrez Milena
Published: July 2017

Este artículo propone un acercamiento a Viaje a Nicaragua (1987), único poemario que firmaron juntos los poetas origenistas cubanos Cintio Vitier y Fina García Marruz, abordando el contexto político y cultural en que el libro se escribe, las motivaciones que propician su escritura, su temática y propuestas estéticas y políticas y sus vínculos con el exteriorismo de Ernesto Cardenal y, de manera particular, ensaya una aproximación a la poética singular de Fina García Marruz y a sus entrevisiones  a partir del análisis y comentario de varios poemas incluidos en el libro.
Etelvina Astrada, estar en España para estar en Argentina. La ideología en apertura de una poeta coherente
Authors: Eguia Bibiana Leonor
Published: July 2017

Este trabajo busca un acercamiento hacia la escritura de la poeta Etelvina Astrada, nacida en Córdoba y exiliada en Madrid desde 1975. Su obra, publicada en totalidad en Europa, resulta injustamente desconocida en su provincia natal. La escasa tirada de sus libros y su circulación fuera del país, las enormes dificultades que vivió durante la época de la dictadura militar más la acción natural del tiempo que profundiza las distancias geográficas; aportan al desconocimiento de sus coterráneos. El hecho se advierte como negativo, en tanto que la escritora hizo un gran aporte de ideas, valores y entrega a la cultura argentina de la resistencia.
Metamorfosis del vuelo: (im)posibilidad cognitiva y movilidad simbólica en la poesía de Rómulo Bustos Aguirre
Authors: Santos Emiro Rafael
Published: July 2017

En este artículo presentamos una lectura de las relaciones entre poesía y conocimiento en la obra del poeta colombiano Rómulo Bustos Aguirre (Santa Catalina de Alejandría, 1954). Examinamos cómo su re-escritura de las figuras arquetípicas de Ícaro y el Ángel encarnan los límites del conocimiento conceptual y místico; y cómo la ironización de los centros tradicionales del pensamiento occidental (entre ellos la filosofía y la ciencia), construye un tipo de saber caracterizado por una conciencia metamórfica de la realidad. El discurso poético se corresponde así con un mecanismo de desentrañamiento y renovación imaginativa de la percepción que integra formas propias y alternas de conocimiento.
La poesía de Victoria Guerrero, un arte de la incomplacencia
Authors: Salazar Ina
Published: July 2017

Este artículo presenta la obra de Victoria Guerrero (Lima, 1968) una de las voces más singulares y potentes de la actual poesía peruana, postulando que la escritura que propone, nutrida por la energía y las conquistas de las vanguardias y neovanguardias, por sus sueños de comunión de arte y vida,  pero desde el desencanto y la resistencia, únicas líneas de conducta y de palabra en el naciente siglo XXI peruano y globalizado produce nuevas coordenadas para la poesía en la conjugación de la exigencia de una conciencia ético-política y de una afirmación genérica.
Introducción: Poesía latinoamericana desde los años 70: voces interiores y espacios sociales
Authors: Usandizaga Lleonart Helena
Published: July 2017

Introducción dossier "Poesía latinoamericana desde los años 70: voces interiores y espacios sociales"
Effects of granulocyte colony-stimulating factor treatment in children and patients with cerebral palsy: a preliminary report
Authors: Paszko-Patej G. , Kułak W. , Okurowska-Zawada B. , Sienkiewicz D. , Wojtkowski J. , Sochoń K. , Kalinowska A. , Okulczyk K. , Topór E. , Mirska A.
Published: July 2017

neuroinflammation and apoptosis in brains affected by cerebral palsy could be therapeutic targets. Granulocyte colony-stimulating factor (G-CSF) exerts anti-inflammatory and antiapoptosis effects and stimulates the proliferation of neural stem and progenitor cells in the brain.
Purpose: To assess the efficacy and safety of G-CSF treatment in children and adolescents with CP.
Materials and methods: Six patients with spastic tetraplegia CP aged 3-15 years were enrolled in this study. Five patients had GMFCS (Gross Motor Function Classification System) level at V, three children had epilepsy, and three had severe mental retardation. We used the gross motor function measure-66 (GMFM-66) to assess motor function.GCSF (5μg/kg/body/day) was administered subcutaneously for five consecutive days during the four months. The parents also evaluated the physical and mental development of their children.
Results: We observed improvement in motor function in patients with CP on the GMFM-66 scale. Parents reported improvement in behavior, speech development, and a decrease in spasticity in children with CP. G-CSF therapy was well-tolerated. No side effects were observed during the study.
Conclusions: Our preliminary report suggests that G-CSF treatment improves motor and mental function in patients with CP. Further studies are needed to confirm these observations
Drug susceptibility of Candida isolated from the surfaces of mobile phones and hands
Authors: Kordecka A. , Krajewska-Kułak E. , Łukaszuk C. , Kraszyński M. , Kraszyńska B.
Published: July 2017

Introduction: The mycological literature currently devotes much attention to the issue of reduced fungal susceptibility to commonly used antifungal drugs. Purpose: To assess drug susceptibility of Candida strains isolated from samples collected from the surfaces of mobile phones and the hands of their owners. A total of 175 mobile telephones belonging to students and lecturers of the Medical University of Bialystok and University Hospital personnel as well as 175 hands of these phone owners were included in the mycological evaluation. Results: The rate of Candida contamination of personal mobile phones was more than 70.0%. C. glabrata strains were primarily isolated from the collected material (89.1% - hands; 74.9% - mobile phones). C. albicans strains showed susceptibility to most antimycotics, with the highest susceptibility to 5-fluorocytosine, and the lowest to fluconazole. C. glabrata showed the lowest susceptibility to fluconazole and miconazole, and the highest to ketoconazole. C. krusei were relatively very sensitive to antibiotics, except for fluconazole. None of the isolated strains showed resistance to more than three types of drugs. Conclusion: This study demonstrated that mobile phones are potentially vehicles for pathogenic Candida strains in a university and hospital settings.
Selected nutritional behaviors and physical activity among elementary school children
Authors: Zalewska M. , Zubrycki A. , Sosnowski Zenon , Jamiołkowski J. , Zakrzewski M. , Maciorkowska E.
Published: July 2017

Introduction: Proper nutrition and physical activity are very important elements in the proper functioning and development of children. The lack of daily, systematic physical effort in younger and younger age groups is a public health problem. Purpose: To evaluate the nutrition and physical activity of children attending primary school. Materials and methods: The study was conducted among 707 pupils form randomly selected elementary schools using the authors’ own questionnaire in the school year 2013/2014. The questionnaire included questions on selected dietary habits and physical activity as well as the socio-economic conditions of the families. Results: Among the studied children, 88.6% consumed 4 or 5 meals a day. There was a statistically significant relationship between the number of meals consumed and the age of the children. Breakfast was consumed by 86.4% of children, more often residents of the city than the village (88.0% vs. 81.7%, p <0.05). Daily consum-ption of second breakfast was declared by 71.5% of boys and 74.2% of girls. The vast majority of the studied students (86.8%) have always taken part in physical education classes. Outdoor leisure time was declared by 75% of the surveyed children. Rural students showed greater involvement in outdoor activities than students from the city (86.1% vs. 70.2%, p <0.001). A total of 62.2% of boys and 51.8% of girls (p <0.05) participated in sports activities. Conclusions: Inappropriate nutrition and lack of physical activity affected both girls and boys, and the abnormalities were dependent on where they lived and were age-related.
Genetic similarities of Escherichia coli isolated from hospitalized patients
Authors: Żórawski M.J. , Dudzik D. , Musiałowska D.
Published: July 2017

Introduction: Escherichia coli is a component of human physiological flora. Pathogenic E. coli strains are a significant etiologic factor for numerous infections, mainly the urinary system, digestive system, respiratory system as well as bacteraemia and post-operative infections. Purpose: To compare the genetic similarity of Escherichia coli strains, isolated from biological material collected for routine microbiological diagnostics. Materials and methods: The examination performed on the Escherichia coli strains, isolated from material collected from patients hospitalized in various clinics and delivered for routine laboratory diagnostics. The analysis was conducted using the ADRSSR method.Results: As a result of the analysis of genetic similarities of examined strains using the ADRSSR method, nine clones were distinguished, clones A and B considered being most numerous. Clone A was predominant in samples from internal diseases clinics while cloning B – from neonatological clinics. Conclusions: The results point to a significant role of monitoring of homogeneity of bacteria strains isolated in the range of the health care providers. It is directly connected with the safety of hospitalized patients as well as effectiveness and course of the treatment. The use of the ADSRRS method gives the opportunity of early detection of the moment of colonization in the monitored place
Herpes simplex encephalitis – diagnostic imaging
Authors: Tyrakowska-Dadełło Z. , Kułakowska A. , Zajkowska J. , Pancewicz S. , Tarasów E.
Published: July 2017

The phenomena of neuroinvasiveness, latency and reactivation are characteristics of the Herpes simplex virus (HSV). The Herpes simplex encephalitis (HSE) prevalence rate is 1 up to 3 in a million cases, which is about 10-20% of all viral encephalitis cases. The course of the disease shows the prodromal period and the symptomatic one; the clinical course is usually rapid and may lead to sudden death. As for the symptomatic period, there are usually neurological focal symptoms and seizures as well as fluctuating consciousness leading to coma. The mortality rate in the course of HSE in non-treated individuals reaches up to 70%, it is lowered to 15% with early treatment with Acyclovir. However, most patients present persistent neurological and cognitive disorders. There are usually no changes in the CT scan as far as the early stage of the disease is concerned. Thus, the imaging technique of choice is MR scan, which shows the changes already on the second day after clinical symptoms. On the basis of MR scans, more or less symmetrical hyperintense cortical and subcortical white matter lesions occur on T2-weighted images with gyral and/or leptomeningeal contrast enhancement. MR spectroscopy can be helpful in lesion diagnosis and monitoring, while diffusion-weighted imaging (DWI) can be used to evaluate inflammatory process activity. Differentiation of HSE in imaging should consider limbic encephalitis, gliomatosis cerebri, cerebral ischemia, cerebral edema after seizure episodes, and MELAS syndrome (Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like episodes), among others. HSV identification in cerebrospinal fluid by PCR (polymerase chain reaction) method is a confirmation of the diagnosis.
Matrix metalloproteinases in urinary system tumors. Part II - Matrix metalloproteinases in urinary bladder carcinoma
Authors: Młynarczyk G. , Kudelski J. , Darewicz B. , Galewska Z. , Romanowicz L.
Published: July 2017

Matrix metalloproteinases (MMPs), also referred to as matrixines, provide a group of proteolytic enzymes. They belong to the family of endopeptidases that break down elements of the extracellular matrix, resulting in its continuous remodeling. Their activity is regulated at multiple levels, while tissue inhibitors of metalloproteinases play a major role in this process. Metalloproteinases play a significant part in neoplastic processes due to their contribution to local tumor invasion, the formation of distant metastases, as well as to angiogenesis Urinary tract tumors pose a significant diagnostic and therapeutic challenge and their incidence tends to grow every year. The aim of this second part of the review is to describe the urinary system structure and function, and to highlight the contribution of matrix metalloproteinases to the development of urinary bladder tumors
Giant lipoma of the face and neck – a case report
Authors: Bortnik P. , Borys J. , Załęski P. , Stankevich A. , Tryniszewska . E. , Wieczorek P.
Published: July 2017

A 65-year-old patient with multiple lipomas of various body regions presented to the Maxillofacial Surgery Clinic in Bialystok to treat a giant lipoma of the face and neck. After undergoing in-depth diagnostics (CT of this area), the patient was qualified and prepared for planned surgery in the clinic. The treatment of choice was a complete surgical excision of the lipoma. The intra- and postoperative course was uneventful. Postoperative histopathological examination confirmed the tentative diagnosis established on the basis of the fine-needle aspiration biopsy and clinical examination.
Effects of granulocyte colony-stimulating factor therapy for osteogenesis imperfecta: a case report
Authors: Paszko-Patej G. , Sienkiewicz D. , Kułak W. , Okurowska-Zawada B. , Wojtkowski J. , Kalinowska A. , Okulczyk K. , Sochoń K. , Dmitruk E. , Mirska A.
Published: July 2017

Introduction: Osteogenesis imperfecta (OI) is a genetic disorder of increased bone fragility and low bone mass. OI type IV. Materials and methods: We examined the safety and effectiveness of a low dose of analog granulocyte colony-stimulating factor (G-CSF) in a 15-year-old girl OI type IV. G-CSF 5 μg/kg was given subcutaneously, for 5 days/month for 3, 6 and 12 months. Laboratory tests, including blood, biochemical tests were performed, in addition to clinical examination.Results: Clinical examination revealed an increase of muscle strength in the upper and lower limbs between base line and day 6 and 12 months. We found no serious adverse events. Leukocyte levels remained below 38,000/μL. Low dose G-CSF was safe and well tolerated by the patient. Conclusions: A significant increase in muscle strength in this patient may indicate beneficial effects of G-CSF factor in this disorder. These results are inspiring and warrant further studies.
The quality of life in parents raising children with an autism spectrum disorder from Poland, Belarus and France
Authors: Ślifirczyk A. , Krajewska - Kułak E. , Brayer A. , Sobolewski M. , Maciorkowska E.
Published: July 2017

Purpose: To assess the health-related quality of life (HRQL) in parents of children with autism spectrum disorder (ASD).
Materials and methods: The sample consisted of 83 families with children with ASD, including 30 families from Poland, 25 from Belarus, and 28 from France. Parental HRQL was surveyed with the World Health Organization Quality of Life–BREF (WHOQOL–BREF) and KINDLR questionnaires.
Results: This study showed that Polish parents reported the lowest quality of life according to the WHOQOL–BREF. Parents from Belarus reported slightly worse HRQL than parents from France, though other aspects of quality of life (e.g, social sphere, somatic sphere) did not differ significantly between these parents. Parents from Poland also reported lower HQOL according to the KINDLR questionnaire, while parents from Belarus had a higher HQRL in the mental, physical, and self-esteem domains compared to parents from Poland and France. Conclusion: Parents from Poland with children with ASD reported lower HRQL both on the WHOQOL–BREF and KINDL R questionnaires compared to parents from Belarus and France.
Indoor air studies of fungi contamination in two kindergartens in Kavala, Greece
Authors: Łukaszuk C. , Krajewska-Kułak E. , Chatzopulu A. , Theodosopoulou E.
Published: July 2017

Introduction: Fungi and moulds are biological hazards that are ubiquitous both in the communal and occupational environments. The aim of the study was to assess the presence of airborne fungi in two kindergartens in Kavala, Greece.
Materials and methods: Materials for the tests were: the air samples (in front of the buildings and the selected rooms) of the two kindergartens. The first Kavala kindergarten was located atop a hill and the second in the city center. The air pollution was determined using SAS SUPER 100.
Results: The mean number of fungal colonies isolated from air of the kindergarten rooms in the city center was 478.3±148.4 CFU/m3. The mean number of fungal colonies isolated from air of the kindergarten on the hill was 343.6±188.8 CFU/m3. Aspergillus niger was most frequently isolated in air samples from the kindergarten rooms in the city center, while Penicillium species predominated the kindergarten rooms on the hill. CFU values in the air samples outside the kindergartens were higher in the center than on the hill of Kavala.
CFU values of the examined air samples are varied. In the kindergarten rooms in the center of Kavala the most frequently isolated species was Aspergillus niger, and in the kindergarten on the hill it was Penicillium species.
Conclusions: The present study demonstrated considerable numbers of fungi in the air in two kindergartens in Kavala, Greece.
Thyroid functioning, adipocytokines, bone turnover and vitamin D - review of literature
Authors: Koszowska A. , Brończyk-Puzoń A. , Dittfeld A. , Nowak J. , Kulik-Kupka K. , Zubelewicz-Szkodzińska B.
Published: July 2017

The most common public health problems include, among others, overweight, obesity, and cardiovascular diseases. In addition, the number of people with thyroid disturbances is still growing. Thyroid abnormalities can lead to many metabolic dysfunctions, including secondary osteoporosis, alterations in body mass, lipid profile, and insulin resistance. Recently, the studies have been focused on the connections between thyroid gland function, obesity, metabolic syndrome and cardiovascular diseases, as well as bone turnover. Fatty tissue plays an important role in whole body homeostasis. Adipose tissue hormones, such as leptin, resistin and adiponectin are proteins having immunomodulatory
lproperties, and their balance is needed to control immune response, as well as inflammation processes. The following article constitutes a review of literature concerning thyroid function with regard to adipocytokines and vitamin D, as well as the influence of this gland on the skeletal system. For this purpose, Medline Pub Med base and Google Scholar were used. All the citied studies in this review article underline how much should be done to achieve more efficient treatment of thyroid disorders, specifically, how to prevent its complications, for instance, osteoporosis, over-weight, obesity or cardiovascular diseases.
Percepção do cuidado centrado na família em unidade neonatal
Authors: Balbino Flavia Simphronio , Meschini Gabriela Ferreira Gomes , Balieiro Maria Magda Ferreira Gomes , Mandetta Myriam Aparecida
Published: July 2017

Doi: 10.5902/2179769216340Objetivo: estudo com o objetivo de compreender a percepção da família do recém-nascido hospitalizado em unidade neonatal em relação ao cuidado prestado pela equipe de saúde. Método: pesquisa qualitativa, descritiva, que utilizou como referencial teórico os pressupostos do Cuidado Centrado no Paciente e Família. A coleta de dados foi realizada por meio de entrevistas semiestruturadas com sete familiares de recém-nascidos internados em uma unidade neonatal de um hospital universitário em 2011. Resultados: Os dados foram analisados conforme a Análise Qualitativa de Conteúdo, emergindo duas categorias analíticas: satisfação com o cuidado na unidade e dificuldades enfrentadas em relação à equipe e à hospitalização. Conclusão: há uma distância entre a teoria e a prática, sendo o Cuidado Centrado no Paciente e Família um ideal a ser alcançado.
Autoeficácia em amamentar de mulheres no pré-natal e no pós-parto: estudo longitudinal
Authors: Uchoa Janaiana Lemos , Rodrigues Andressa Peripolli , Joventino Emanuella Silva , De Almeida Paulo César , Oriá Mônica Oliveira Batista , Ximenes Lorena Barbosa
Published: July 2017

Objetivo: comparar as médias dos escores de autoeficácia em amamentar das mulheres no pré-natal e no pós-parto com as variáveis da gravidez, do parto, do puerpério e relacionadas ao aleitamento materno. Método: estudo longitudinal do tipo painel, que avaliou 50 mulheres no pré-natal e puerpério em 2011, utilizando a Breastfeeding Self-Efficacy Scale – Short-Form e um formulário com dados da gravidez, parto e puerpério. Resultados: apresentaram relação com autoeficácia em amamentar: gravidez planejada; realizar seis ou mais consultas pré-natais; realizar a preparação das mamas para amamentar; pretender amamentar o filho; participar de grupo de gestantes; parto vaginal em hospital público; amamentar na primeira hora de vida e de forma exclusiva na maternidade e na alta hospitalar; não ter dificuldades para amamentar. Conclusão: diversos fatores podem influenciar a autoeficácia, sendo relevante promover o aleitamento materno no pré-natal, estimular esta prática e prestar às mães esclarecimentos a respeito da alimentação do filho.
Riscos para complicações cardiovasculares em portadores de diabetes mellitus
Authors: Kreuzberg Jéssika Taciane Nogueira , Aguilar Antonio Marcos Moreira , Lima Monia Maia
Published: July 2017

Objetivo: estratificar o risco para complicações cardiovasculares em pacientes diabéticos cadastrados em uma Estratégia de Saúde da Família do município de Primavera do Leste/Mato Grosso. Método: Pesquisa descritiva de abordagem quantitativa, de campo e de análise secundária, realizado com pacientes diabéticos cadastrados no Programa HIPERDIA. Resultados: participaram 52 pacientes, com predomínio do sexo feminino, faixa etária entre 50 e 60 anos, escolaridade inferior a sete anos de estudo. Dentre os participantes, 48 pacientes apresentava diabetes tipo II (92,3%), 45 (86,5%) faziam uso de hipoglicemiante oral e 38 (73%) apresentava hipertensão arterial sistêmica associada. Ambos os sexos mantinham uma dieta inadequada. Quanto à percepção do tratamento, todos consideravam importante o controle da patologia. O sexo masculino apresentou alto risco para doença cardiovascular e as mulheres, em sua maioria, risco intermediário. Conclusão: reeducação alimentar e educação em saúde são importantes no controle da doença e redução de possíveis complicações.
Nível de estresse entre enfermeiros de um hospital da região Centro-Oeste – RS
Authors: Kirchhof Raquel Soares , Oshõa Lisiane Marques , Bubltz Susan , Lopes Luis Felipe Dias , Squiavenato Maria Catarina De Almeida
Published: July 2017

Objetivo: verificar o nível de estresse entre enfermeiros de um hospital. Método: estudo transversal, desenvolvido em hospital de médio porte no interior do Rio Grande do Sul. A população foi de 20 enfermeiros. A coleta ocorreu em outubro de 2014, por meio da Escala Bianchi de Stress, constituída por caracterização sociodemográfica e 51 itens para avaliar estresse, divididos em seis domínios. O estudo teve aprovação do Comitê de Ética em Pesquisa da Universidade Regional Integrada do Alto Uruguai e das Missões. Resultados: dentre os enfermeiros, 55% apresentaram médio nível de estresse. Os maiores escores foram nos domínios: Administração de pessoal, Coordenação das atividades da unidade e Condições de trabalho. Conclusão: o nível de estresse foi médio para pouco mais da metade da população. Sugerem-se outros estudos com populações maiores para comparações e fortalecimento das investigações acerca da saúde e das condições de trabalho na enfermagem.
Compreensão do sentimento materno na vivência no método canguru
Authors: Heck Graziella Marjorie Moreira , Lucca Huiana Cristine , Costa Roberta , Junges Carolina Frescura , Santos Simone Vidal , Borck Márcia
Published: July 2017

RESUMO: Objetivo: compreender os sentimentos maternos vivenciados nas diferentes etapas do Método Canguru. Método: estudo descritivo, qualitativo, desenvolvido em uma unidade neonatal de um hospital escola no sul do Brasil, com a participação de nove mães. A coleta dos dados ocorreu no segundo semestre de 2013, quando foram aplicadas entrevistas semiestruturadas. Os dados foram submetidos à análise de conteúdo. Resultados: emergiram as seguintes categorias: Expectativas do nascimento: Nascer a termo, Aproximação da mãe com o bebê, Sentindo-se mais mãe e Quando cheguei em casa. Conclusão: os sentimentos maternos relacionam-se intimamente com o grau de conhecimento e adaptabilidade da mãe. Cabe ao profissional de saúde fornecer informações e apoio de forma individualizada, respeitando a história de cada mãe e sua família.
Avaliação e classificação de risco: tempo de espera dos usuários de baixa gravidade
Authors: Oliveira Gabriella Novelli , Oca Sylvia Regina Cavalcanti , Campanharo Cassia Regina Vancini , Okuno Meiry Fernanda Pinto , Lopes Maria Carolina Barbosa Teixeira , Batista Ruth Ester Assayag
Published: July 2017

Objetivo: identificar se o tempo transcorrido entre a classificação de risco e o atendimento médico para os pacientes de menor gravidade estava de acordo com o protocolo institucional. Método: estudo transversal descritivo. Realizado no Serviço de Emergência de um hospital público, universitário e de alta complexidade no período de março a junho de 2012. A amostra constituiu de 172 pacientes, com idade a partir dos 12 anos, classificados nas cores: amarela, verde e azul, segundo o protocolo da instituição. Resultados: de acordo com o protocolo institucional 66% dos pacientes foram classificados na cor verde. Observou-se que o tempo médio de espera, dado em minutos, estava dentro do preconizado nas três cores de classificação: amarela 40,68, verde 53,76 e azul 69,06. Conclusão: o tempo médio de espera para o atendimento médico não ultrapassou aquele preconizado pelo protocolo do serviço de emergência em nenhuma das cores de classificação.