bluuebunny/crossref_metadata_2025 huggingface dataset:
Occurrence of tire-derived microplastics (TMPs) focusing on driving behavior
Authors: Nishimagi Chisato , Yanagihara Masami , Fang Yiming , Sakai Hiroshi
Published: February 2023

Recently, microplastic (MP) contamination of the aquatic environment has been reported. Marine MP pollution (especially terrestrial-sourced MPs derived from vehicle tires) is considered a global problem because marine organisms may ingest toxic substances. In this study, we analyzed the generation and occurrence of tire-derived MPs (TMPs) that originate from tire dust on roadways and also focused on driving behavior. The results suggested that the number of TMPs increased in proportion to the increase in traffic volume within the range of 10,000–30,000 vehicles/day. The influence of driving behavior was explored by comparing the number of TMPs at distances of 30, 50 and 70 m from the stop line and by assuming a difference in braking behavior. Traffic video was recorded in conjunction with sampling and was analyzed in parallel with the TMPs. The results demonstrated that brakes were applied for an acceleration rate of over −10 m/s2 at distances of 60 and 80 m from the stop line, which resulted in an approximate increase of 28% in the number of TMPs at approximately 70 m. With these results, it can be concluded that the number of TMPs increases due to the traffic volume and braking behavior.
Start-up of non-bioaugmented pumice biofilters in flow-through and recirculating flow regime for Mn removal
Authors: Araya-Obando José Andrés , Rietveld Luuk C. , Kelly-Coto Daniel E. , Quesada-González Andrea , Caballero-Chavarría Andrey , Romero-Esquivel Luis G.
Published: February 2023

Biofilters are effectively used for drinking water treatment. However, the long ripening time of virgin media for manganese (Mn) removal is a major concern. In this study, the influence of the flow regime on the ripening time of virgin pumice medium was investigated. For this purpose, pilot-scale experiments were performed to compare the start-up of flow-through and recirculating filter columns using inherent inoculation with the same groundwater source. The systems were operated at 2 m·h−1 with gradual flow increments up to 5 m·h−1 and avoiding Fe-loading. Effective Mn removal (>90%) in flow-through and recirculating columns was achieved after 8 and 23 days, respectively. Flow-through columns reached compliance with a local drinking water criterion (Mn < 0.1 mg·L−1) at 15 cm filter depth in 11 days. Recirculating filter columns required 32 days to reach compliance at 30 cm depth. The start-up in recirculation regime resulted in a water consumption reduction of about 50% compared with flow-through regime. The intermittent provision of the Mn-loading in recirculating regime impacted the Mn-oxidizing bacteria (MOB) concentration in the pumice stone medium. Both flow regimes required a similar total Mn-loading (0.16 and 0.11 kg·Mn·m−2, respectively), suggesting that Mn-loading was the limiting factor for the ripening of pumice.
Prefiguración del sujeto migrante y LGTBI+ en la normativa chilena sobre migración y diversidad sexual
Authors: Stang María Fernanda , Galaz Valderrama Caterine , Lara Edwards Antonia
Published: February 2023

A partir de un corpus compuesto por textos normativos de Chile referidos, por una parte, a las migraciones internacionales (de 1975 y 2021) y, por la otra, a la diversidad sexo-genérica (de 2012 y 2018), este artículo se propone analizar el modo en que se construyen prefiguraciones del sujeto migrante y del sujeto de las disidencias y diversidades genérico-sexuales, además de sus implicaciones para las personas migrantes LGBTI+. El abordaje se realiza desde el análisis crítico del discurso feminista, y permite observar prefiguraciones que adoptan un posicionamiento de reificación identitaria unidimensional, que conciben a este sujeto, por un lado, exclusivamente como migrante económico hetero-cis-normado y, por el otro, como minoría genérico-sexual vulnerable, lo que implica un borramiento de las personas migrantes LGBTI+ y de las desigualdades específicas que les afectan.
Design of Multitarget Inhibitors as Tracheal Smooth Muscle Relaxants
Authors: Bhatia Neela M. , Bhatia Manish S. , Mohanty Sibaprasad K. , Parulekar Rishikesh S. , Joshi Amruta V. , Ashtekar Snehal S.
Published: February 2023

Introduction:

Asthma complications and adverse effects associated with steroidal therapy
highlight the need for non-steroidal compounds intercepting asthmatic pathophysiology at multiple
targets. The present investigation was carried out to evaluate the tracheal smooth muscle relaxant effect
of virtually designed, combinatorially synthesized polyfunctional N-heteroarylamides.

Methods:

Virtual screening and molecular docking studies of designed compounds were performed
using PyRx and AUTODOCK 4.2 software against molecular targets viz. FLAP, LTB4, and H1 receptor.
Cross-validation of virtual screening results and active site, confirmation was performedusingVlife
MDS software version 3.5. The combinatorial approach was used to synthesize designed compounds in
which heterocyclic amines were reacted with substituted aromatic acid chlorides by nucleophilic substitution
reaction to obtain a 5x5 mini-library. The structures of synthesized leads were confirmed by
infrared and proton magnetic resonance spectroscopic analysis. Synthesized compounds were evaluated
for their smooth muscle relaxation effect on isolated goat tracheal smooth muscle.

Results:

Results were calculated as a percent decrease in contraction response observed using histamine
and LTB4. The tested compounds produced anticipated tracheal smooth muscle relaxant activity.
Based on the results of screening the structure-activity relationships (SAR) have been reported.

Conclusion:

Present study concluded that synthesized polyfunctional N-heteroarylamides have a tracheal
smooth muscle relaxant effect. The mode of action is predicted from the analysis of virtual
screening results. A good correlation was observed between virtual screenings and biological activities
of lead molecules suggesting the rationale used to optimize the structural requirements of a ligand for
selected targets is appropriate.
Stem Cells and Tumor-Killing Virus to Target Brain Tumor: In Pursuit to
Bring a Potential Delivery Vehicle for the Central Nervous System Tumors
Authors: E. Vignesh Balaji , Ranganath Pai K. Sreedhara
Published: February 2023

To target brain cancer, various therapeutic options are present to fight against cancer cells.
But the existing therapies are not showing a proper curation of cancer patients. Henceforth, activating
the immune cells and targeting oncogenes/proteins might be an emerging therapeutic approach to target
and destroy malignant brain tumor. Stem cells (SCs) are considered potential immunomodulators that
trigger the highly suppressed immune system in the tumor microenvironment. Also, engineered SCs can
repress the aberrantly expressed oncoproteins that cause tumor cell proliferation and growth. SCs have
an excellent migration capability to reach the infected site and support the regeneration of damaged
blood vessels and tissues. Likewise, oncolytic virotherapy (OVT) is a promising novel therapeutic molecule
in which genetically modified viruses can selectively replicate and destroy cancer cells without
harming healthy cells. Same as SCs, oncolytic viruses (OVs) tend to stimulate the host's innate and
adaptive immune response to battle against the advanced brain tumor. In clinical studies, various OVs
have shown good immunogenic responses with a high safety profile and tolerability against cancer patients
with reduced morbidity and mortality rate. SCs act as an attractive cargo for OVs which helps to
influence the tumor site and destroy the tumor volume. SCs protect the OVs from systemic degradation
and promote therapeutic efficacy against cancer cells. SCs carried OVs might be a potential therapeutic
way to bring an effective treatment option for brain tumors.
Nature-derived Alkaloids as a Promising Bioactive Compound in Drug Discovery to Meet Global Leishmania Needs
Authors: Sharifi Fatemeh , Mohamadi Neda , Abiri Ardavan , Sharifi Iraj , Harandi Majid Fasihi , Sharififar Fariba
Published: February 2023

Background:

Natural products have been important resources for potential drug development. Among the many classes of natural products, alkaloids have the most therapeutic applications. Treatment of leishmaniasis by chemical drugs remains a challenge because of toxic side effects, limited efficacy, and drug resistance. This review focuses to embrace all researches on leishmanicidal alkaloids over a specific range of time, with special consideration the molecular mechanism of action, and structure-related activity.

Methods:

All publications (in English) from Web of Science, PubMed, Science Direct, Scopus, and Google Scholar from 2000-2021 using a variety of keywords such as natural alkaloids, herbal alkaloids, marine alkaloids along with leishmaniasis were included in the present study. In this summary, the focus is mainly on natural alkaloids of plant, mineral, marine origin, etc., which have empirically demonstrated the antileishmanial effect.

Results:

Fourteen categories of alkaloids with anti-leishmaniasis activity were extracted from the articles. The highest number of alkaloids belonged to isoquinoline, indole, and quinoline alkaloids (21.78%, 20.67%, and 16.48% respectively). This review indicated that the mentioned alkaloids are able to inhibit the proliferation of parasites, the respiratory chain and protein synthesis, arrest the cell cycle, disrupt the mitochondrial membrane integrity, inhibit leishmanial topoisomerase, induce mitochondrial dysfunction, and changes in the parasite morphology.

Discussion:

The present study highlighted antileishmanial alkaloids that are active against different species of Leishmania in vitro and some of them are also active in visceral and cutaneous leishmaniasis models. However, more clinical studies are needed to clarify the anti-leishmanial activity of alkaloids against leishmania in detail.

Conclusion:

Among the reported compounds, two main classes of alkaloids including isoquinoline and indole alkaloids cover a wider range of anti-parasitic compounds, and structure-activity relationships (SAR) studies of these molecular skeletons may be good lead compounds and afford the structural clues to develop novel medicines with more selective therapeutic profiles.
Chimeric Antigen Receptor T-cell Therapy in Cancer: A Critical Review
Authors: Sharma Ravikant , Suravarjhula Lalitha , Banerjee Madhuparna , Kumar Gautam , Kumar Nitesh
Published: February 2023

Targeted cancer therapy acts on targeted molecules, is less toxic to normal cells, and
acts more specifically on cancer cells. The two primary strategies for preventing malignancy
growth are the blocking of T-cell repression signals or forwarding of T-cell to tumor target with
both T and tumor-specific antibodies. The CAR comprises three domains, the extracellular antigen
recognition domain and the intracellular T-cell signaling domain, which participate in activating
T-cells. The two most common adverse effects of CAR T-cell treatment are cytokine release syndrome
(CRS) and cell-associated neurotoxicity syndrome (CANS). The adaptability of intracellular
signaling domains inside CARs allows the cell to counterbalance the downregulation of costimulatory
molecules produced by tumor cells, either indirectly or directly. The major disadvantage
of CAR-T cell therapy is off-target toxicity. Treatment with CARs expressing CD3,
CD123, Lewis Y, CLL-1, CD44v6, FLT3, and folate receptors showed promising results in preclinical
models of acute myeloid leukemia (AML). A recent study has revealed that B7-H3 CART
cells exhibit significant anticancer efficacy in a variety of solid tumor preclinical models, including
PDAC, ovarian cancer, neuroblastoma, and various pediatric malignancies. The notion of
SUPRA CAR, with its unique capacity to alter targets without the need to re-engineer, is a recent
innovation in CAR. Given the importance of NK cells in tumor development and metastatic defence,
NK cell-based immunotherapies, including adoptive transfer of NK cells, have garnered a
lot of interest. With the advancement of improved cellular manufacturing methods, novel cellular
engineering strategies, precision genome editing technologies, and combination therapy approaches,
we firmly believe that CAR-T cells will soon become an off-the-shelf, cost-effective, and potentially
curative therapy for oncogenesis.
Ursolic Acid: Historical Aspects to Promising Pharmacological Actions for
the Treatment of Central Nervous System Diseases
Authors: Singh Aditya , Ansari Vaseem A. , Mahmood Tarique , Ahsan Farogh , Wasim Rufaida
Published: February 2023

Ursolic acid (UA) has been utilized to improve memory-related cognitive processes and
intellectual functions. This study aims to examine the ethnobotanical uses, phytochemical composition,
toxicity, and central nervous system activities of UA. It promotes learning and memory and
has biological effects against Alzheimer's disease, Parkinson's disease, and cognitive impairment,
according to pharmacological investigations. UA did not cause any death, abnormal body weight,
or pathological diseases at any of the test doses. Furthermore, no behavioral, neurotoxin, coagulation,
haematological, or clinical chemistry changes were seen as a result of UA treatment. UA is
also used as a cosmeceutical product to improve skin functions. This article examines all
knowledge that has become available at this time for revealing the chemistry of the current has
been extensively investigated based on the data, resulting in UA derivatives with improved potency,
bioavailability, and stability being used to treat a number of non-communicable diseases. The
pharmacological activity of UA has been exploited to improve learning and memory and treat depression,
emotional stress, fatigue, anxiety, insomnia, Alzheimer’s disease, Parkinson’s disease,
epilepsy, and schizophrenia. The effects of UA on the central nervous system detailed in this review.
The majority of UA studies have been preclinical evaluations of cellular mechanisms in the
central nervous system, and more translational clinical research is needed to assess the drug's safety
and efficacy, as well as its favorable, biodistribution, which could be targeted using different
pathways and administration routes. Several in vitro and in vivo studies have investigated the
pharmacological properties of UA reporting neuroprotective effects and improvements in cognitive
function. These effects are attributed to its antioxidant, antiapoptotic, and anti-inflammatory
actions.
A Perspective into “TEL”-Tenofovir, Emtricitabine and Lamivudine
Antileprotic Activities by Drug Repurposing and Exploring
the Possibility of Combination Chemotherapy with Drug Rescued
Molecules for a Leprosy Free Mankind
Authors: Thangaraju Pugazhenthan , Yella Sree Sudha Tanguturi , Ramamurthy Vijayakumar Arumugam , Navabshan Irfan , Mohamed Thameemul Ansari Lappathai Habeeb
Published: February 2023

Background:

Since leprosy bacilli cannot grow in vitro, testing for
antimicrobial resistance against Mycobacterium leprae or assessing the anti-leprosy
activity of new drugs remains hard. Furthermore, developing a new leprosy drug through
the traditional drug development process is not economically captivating for
pharmaceutical companies. As a result, repurposing existing drugs/approved medications
or their derivatives to test their anti-leprotic potency is a promising alternative. It is an
accelerated method to uncover different medicinal and therapeutic properties in approved
drug molecules.

Aims:

The study aims to explore the binding potential of anti-viral drugs such as
Tenofovir, Emtricitabine, and Lamivudine (TEL) against Mycobacterium leprae using
molecular docking.

Methods:

The current study evaluated and confirmed the possibility of repurposing antiviral
drugs such as TEL (Tenofovir, Emtricitabine, and Lamivudine) by transferring the
graphical window of the BIOVIA DS2017 with the Crystal Structure of a
phosphoglycerate mutase gpm1 from Mycobacterium leprae (PDB ID: 4EO9). Utilizing
the smart minimizer algorithm, the protein's energy was reduced in order to achieve a
stable local minima conformation.

Results:

The protein and molecule energy minimization protocol generated stable configuration
energy molecules. The protein 4EO9 energy was reduced from 14264.5
kcal/mol to -17588.1 kcal/mol.

Conclusion:

The CHARMm algorithm-based CDOCKER run docked all three molecules
(TEL) inside the 4EO9 protein binding pocket (Mycobacterium leprae). The interaction
analysis revealed that tenofovir had a better binding molecule with a score of -
37.7297 kcal/mol than the other molecules.
effect of deep breathing relax technique on labor pain intensity in the active phase
Authors: Muldaniyah Muldaniyah , Wahyuni Indah Sri , Malinda Risnati , Susanti Neny Yuli , Fitria Lia
Published: February 2023

Labor pain is a combination of physical pain due to myometrial contractions accompanied by stretching of the lower segment of the uterus fused with the psychological condition of the mother during labor. The purpose of this study was to determine the effect of deep breathing relax technique on labor pain intensity in the active phase. Quasi-experimental Research Design with pre and post test without control. The sample in this study were 16 people. Sampling with purposive sampling method. The results of the research distribution of respondents before Deep Breathing Relax was mostly felt severe pain and after being given Deep breathing relax treatment most respondents experienced moderate to mild pain with a paried t test value of P = 0.000 < ? 0.05 thus there is an effect of deep breathing relax technique on labor pain intensity in the active phase.
QUEUEING SYSTEM IN FAIR PRICE SHOP OF KERALA TO MITIGATE WAITING TIME AND OPTIMIZATION OF SERVERS
Authors:   Presidency University, Sasi Ms. Archana , Subramanian Dr. Thiruselvan , Ravichandran Dr. Sathish Kumar
Published: February 2023

Queues are a typical occurrence in everyday life, particularly during peak hours in Fair Price Shops (FPS), government offices, banks, post offices, super markets, hospitals, and clinics. The arrival rate, service rate, and server usage all play a role in the queueing process of any system. We expect a balance between waiting time and server utilization in an effective system, with the ideal being less waiting time and maximum server utilization. This paper investigates efficient queue management in FPS using M/M/C queueing model. The major goal of this research is to minimize customer waiting time in the FPS with the minimal number of servers. It demonstrates the application of the simulation modelling as a method for optimizing the number of servers in a specific FPS in Kerala, India. The model was developed to provide the outcomes of system parameters like arrival rate, waiting time and server utilization.
Teaching and Learning Third Languages
Authors: D'Angelo Francesca
Published: February 2023

Contributing to emerging research on third language acquisition, this book presents readers with a practical guide to understanding how these languages are processed, learned and taught. With examples from a range of learning contexts, it emphasises the role of teachers as bridges between education and research on multilingualism.
A COMPARATIVE ANALYSIS AND THE QUALITY ASSESSMENT OF HIGHER SECONDARY EDUCATION IN NAGALAND
Authors: Parhi Hare Krushna
Published: February 2023

Higher secondary education means the education which is imparted in class eleven and twelve. It is that level of education where the adults decide among themselves about the future of their life. The foundation of higher learning builds in this stage. This stage of education is so vital that many students join different professional courses just after completion of their higher secondary in order to get employment and start their life. In the present context, quality higher secondary education becomes mandatory to compete in the global market. In this study, an attempt has been made to know the quality of higher secondary students through their academic achievement (result) in the examination, different streams of studies provided in the institutions of different districts, the ratio of students studying in govt. and private institutions and to compare and contrast between number of students opting for arts, science and commerce. This study is descriptive in nature basing on secondary data collected from various sources. In this study the investigator has found number of findings such as i) academic achievement (results) of govt. higher secondary institutions in three streams (arts, science and commerce) until 2017 was satisfactory, ii) since 2018, quality of academic achievement (results) of private higher secondary institutions are better than govt. higher secondary and the students enrollment in govt. higher secondary has been decreasing in a rapid rate, iii) female students in all three streams of studies performed better results than male students in last three years, iv) there is a disparity in providing three streams of studies in the entire state. Most of the institutions (private and govt.) are established in Dimapur and Kohima, v) private agencies are the main player of higher secondary education in the state and vi) there is very less opportunities of science and commerce studies in the entire State etc.
STUDY HABITS AND GENERAL WELL-BEING IN RELATION TO MOBILE PHONE USAGE AMONG SECONDARY SCHOOL STUDENTS
Authors: Kaur Navdeep . , Sharma Jyoti  .
Published: February 2023

The purpose of the present study is to investigate the studyhabits and general well- being in relation to mobile phone usage among secondary school students. The study also examined the difference between study habits and general -well being in relation to mobile phone usage with respect to locale and gender. To conduct study 200 respondents from Amritsar City were selected. The study revealed that there is significant relationship between study habitsand general well- being of secondary school students. However the study showed negative relationship between general well -being and mobile phone usage.
TECHNICAL QUALITIES IN THE POETRY OF EMILY DICKINSON
Authors: Joshi Manish .
Published: February 2023

Dickinson’s reputation as a poet is based not only on the contents of her poetry but also on her art and technique. No American poet attracted the attention of scholars and critics with his or her technical qualities as Dickinson did. Although, unlike Wordsworth, Matthew Arnold and T.S Eliot, she had no formal theory of poetics for writing poetry but her art and technique of writing poetry have been the subjects of discussion among many critics like James Reeves and Douglas Duncan. It was due to her fastidious nature that she did not learn the secrets of poetic art from any poet or critic. She never had the benefit of accomplished poetic guidance. She wrote to Higginson that so far as the writing of poetry is concerned, she had none to ask. This is why, there are many technical defects in her poetry but these defects are a part of her originality as a poet. She composed by instinct which told her that mechanical regularities disturb the free flow of thoughts. As a poet, she depended on inspiration and in the absence of inspiration, she failed to write good poetry. The following poem is the result of labour and, as such, it does not possess poetic excellence:
GUIDANCE NEEDS OF SECONDAY SCHOOL GIRL STUDENTS IN BORDER AREAS OF AMRITSAR DISTRICT: A SURVEY
Authors: Kaur Gagandeep . , Kaur Navdeep .
Published: February 2023

We require direction in a variety of areas. Guidance in different area help us to achieve goal without wasting our time. This study aims to examine the guidance needs of secondary school girl students of border area of Amritsar District. The investigator has adopted the survey method of research. For the present study, the sample consisted of total 300 girl students which was selected through simple random sampling technique. Guidance Needs Inventory (GNI) prepared by Grewal (2010), was used to identify the type and strength of guidance needs of secondary school girl in five areas – Physical, Social, Psychological, Educational and Vocational. Statistical techniques Mean, S.D, t-test and one- way Anova were used. The findings of the study revealed that all girl students of border area who study in government and private school have extreme need of guidance in vocational area. In Physical, Social, Psychological and Educational area secondary school girl students of border area need high guidance. All girl students (government and private school and different category) of border area want dire need of guidance in all areas. Further it was found that there was no significant difference between guidance needs of secondary school girl students with respect to type of school and category. For the fulfillment of the guidance needs school management should organize sports, yoga, NSS camp in school. Teacher should motivate the all the students to participate in co-curricular activities and develop the healthy habits in students like importance and management of time, significance of balanced diet and physical exercises. Teacher should provide sex education to the child and develop the self-confidence through different activities like drama, debate. In the classroom, teacher should provide democratic environment to the students so that they give their own point of view in front of teacher.
NEW EDUCATION POLICY – 2020
Authors: Mundhe Khushal  Limbraj
Published: February 2023

Education Policy lays particular emphasis on the development of the creative potential of each individual. It is based on the principle that education must develop not only cognitive capacities - both the ‘foundational capacities ’of literacy and numeracy and ‘higher-order’ cognitive capacities, such as critical thinking and problem solving – but also social, ethical, and emotional capacities and dispositions. The Digital India Campaign is helping to transform the entire nation into a digitally empowered society and knowledge economy. While education will play a critical role in this transformation, technology itself will play an important role in the improvement of educational processes and outcomes; thus, the relationship between technology and education at all levels is bidirectional. National Education Policy 2020 recognizes the importance of leveraging the advantages of technology while acknowledging its potential risks and dangers. It calls for carefully designed and appropriately scaled pilot studies to determine how the benefits of online/digital education can be reaped while addressing or mitigating the downsides. In the meantime, the existing digital platforms and on-going ICT-based educational initiatives must be optimized and expanded to meet the current and future challenges in providing quality education for all.
उच्च प्राथमिक स्तर के विद्यार्थियों में नागरिक बोध के विकास में बाल संसद की भूमिका
Authors: . हर्षवर्धन . , बाजपेयी सुहासिनी  .
Published: February 2023

प्रस्तुत शोध पत्र में उच्च प्राथमिक विद्यालय के विद्यार्थियों में नागरिक बोध के विकास में बाल संसद की भूमिका का अध्ययन किया गया है। इस शोध अध्ययन के उद्देश्य उच्च प्राथमिक विद्यालय के विद्यार्थियों में नागरिक बोध के विकास में बाल संसद संचालित एवं बाल संसद विहीन विद्यालयों की प्रभाविता का अध्ययन करना है एवं उच्च प्राथमिक विद्यालय में नागरिक बोध के विकास में लिंग एवं क्षेत्र के आधार पर बाल संसद की प्रभाविता का अध्ययन करना है। प्रस्तुत शोध में जनसंख्या के रूप में उत्तर प्रदेश के प्रयागराज एवं नैनी जिले के सरकार द्वारा संचालित उच्च प्राथमिक विद्यालयों के कक्षा.8 के अध्ययनरत सत्र.2021.2022 के विद्यार्थियों को चुना गया है तथा उद्देश्यपूर्ण विधि से प्रतिदर्श के रूप में 13 उच्च प्राथमिक विद्यालयों में से कुल 480 विद्यार्थियों का चयन किया गया है जिसमें बाल संसद संचालित विद्यालय के विद्यार्थियों की संख्या 237 एवं बाल संसद विहीन विद्यार्थियों की संख्या 243 है। आंकड़ों का संकलन करने के लिए स्वनिर्मित नागरिक बोध मापनी का निर्माण किया गया है तथा प्राप्त आंकड़ों का विश्लेषण एवं सार्थकता स्पष्ट करने के लिए विवरणात्मक सांख्यिकी का प्रयोग किया गया है। शोध निष्कर्ष में यह पाया गया कि नागरिक बोध के विकास में बाल संसद संचालित एवं बाल संसद विहीन विद्यालय के विद्यार्थियों की अभिवृत्ति में सार्थक अंतर है। नागरिक बोध के विकास में बाल संसद संचालित लड़कों एवं बाल संसद लड़कियों की अभिवृत्ति में सार्थक अंतर है। जबकि नागरिक बोध के विकास में बाल संसद संचालित शहरी क्षेत्र के विद्यार्थियों एवं बाल संसद संचालित ग्रामीण क्षेत्र के विद्यार्थियों की अभिवृत्ति में कोई सार्थक अंतर नहीं है।
शिक्षणशास्त्र विद्यार्थी.शिक्षकांमध्ये बहुभाषिकता कार्यक्रमाचे विकसन व परिणामकारकता
Authors: रणदिवे शाम  .
Published: February 2023

1990 च्या नंतर ष्खाउजाष् प्रतिमानाने जागतिक स्तरावर स्थलांतरित होणाऱ्यांचे प्रमाण वाढले व यात भारतीय नागरिकांचा अग्रक्रमाने संदर्भ द्यावा लागेलए विदेशात नोकरी व्यवसायाच्या निमित्ताने स्थलांतर वाढले व विविध देशए धर्म प्रांतातील लोक एकत्र येऊन एक उदयोन्मुख समुदाय आकारास आलाए व हा स्थलांतरितांचा समुदाय बहुसंस्कृतिकए बहुभाषिक स्वरूपाचा होता जिज्ञासू मानवी मनाने सतत अभ्यास चिंतनातून बहुभाषिक असण्याचे महत्त्व अधोरेखित केले आणि आंतरराष्ट्रीय स्तरावर बहुभाषावाद असा नवग्रह उदयास आलाण्
प्रतिभाशाली छात्र एवं छात्राआंे के मूल्यों तथा समायोजन का अध्ययन
Authors: मिश्रा श्रद्धा  .
Published: February 2023

प्रतिभाशीलता शब्द एक विशेषण है, जिसका तात्पर्य है कि एक ऐसा व्यक्ति जो विशेष रूप से असाधारण योग्यता या बुद्धि से सम्पन्न हो। प्रतिभाशाली व्यक्तियों पर अध्ययन लेविस तरमन के सन् 1925 के कार्य से प्रारम्भ हुआ, जिसमें उन्होने उच्च योग्यता वाले व्यक्तियों की पहचान करने के लिए बुद्धि परीक्षण का प्रारूप तैयार किया। मूल्य अच्छे और बुरे व्यवहार में फर्क बतलाता है। यह हमारे व्यक्तित्व की पहचान तय करता है। शिक्षा देश के विद्यार्थियों के व्यवहार, चरित्र निर्माण, आदतों को एक नया रूप एवं आकार देता है। यह रूप विद्यार्थियों के जीवन में एक नयी दिशा प्रदान करता है। यदि मूल्यों का प्रभाव विद्यार्थियों के जीवन में न हो तो विद्यार्थियों का जीवन अंधकारमय तथा दिशा विहिन होने की संभावना है। अतः प्रत्येक नागरिक को भी यह जानकारी होना आवश्यक है। प्रत्येक विद्यार्थी मूल्यों का विकास करे तथा इन मूल्यों की प्राप्ति के लिए ठोस कदम अपनायें। आधुनिक युग में मूल्यों की प्रोन्नति प्रत्येक विद्यार्थी के जीवन में शक्ति प्रदान करता है। यह उनके जीवन में दृढ़ संकल्प का बीज होता है जो अपने लक्ष्य की प्राप्ति के लिए विद्यार्थी अपने जीवन को दाव पर लगा सकता है। विद्यार्थियों के जीवन में मूल्यों की प्राप्ति का मूल्यांकन करना अत्यंत महत्त्वपूर्ण है। चूँकि यह भविष्य का नींद या स्तम्भ है। यह उनके लिए एक जवाबदेही और आने वाली पीढ़ी के लिए एक जवाबदेह नागरिक की भूमिका अदा करता है अतः मूल्य शिक्षा न केवल शब्दों में बल्कि कार्यों में परिलक्षित होता है। अतः मूल्य शिक्षा न केवल सैद्धांतिक दृष्टिकोण से बल्कि प्रायोगिक संदर्भ में भी विराजमान है। इस प्रयोगिक मूल्य शिक्षा को उच्च विद्यालय के विद्यार्थियों को भी दी जानी है क्योंकि ये जो आज सीखते हैं उसे कल अपने जीवन में कार्यान्वित करेंगे। समायोजन का अर्थ होता है समाज में एक दूसरे के साथ मिलकर रहना। अतः समायोजन के ही बुनियाद पर मनुष्य जाति प्रगति करता है। विद्यालय समायोजन का होना अति आवश्यक है। सब प्रकार से समायोजित व्यक्ति वह होता है जो पहले तो अपने आप से ही संतुष्ट और समायोजित हो तथा दूसरे अपने चारों ओर फैले वातावरण या परिवेश से उसका सही तालमेल हो। इस दृष्टि से समायोजन के क्षेत्रों को व्यक्ति तथा उसके वातावरण में ही निहित माना जाना चाहिये। एक व्यक्ति की दुनिया जहॉं उसके अपने शारीरिक और मानसिक स्वास्थ्य तथा व्यक्तित्व के महत्वपूर्ण पहलुओं के इर्द-गिर्द घूमती है वहॉं उसे अपने सामाजिक परिवेश तथा काम-काज के क्षेत्रों में भी समायोजित होने की आवश्यकता पड़ती है। समायोजन संबंधी उसकी इन आवश्यकताओं को ध्यान में रखते हुए किसी भी व्यक्ति के समायोजन क्षेत्रों को तीन मुख्य भागों - व्यक्तिगत, सामाजिक तथा व्यवसायिक में बॉंटकर समझने का प्रयत्न कर सकते हैं। व्यक्ति अपने आप से कितना समायोजित है इस बात का निर्णय उसके इस क्षेत्र के समायोज स्तर से ही ज्ञान होता है। कोई व्यक्ति किसी क्षेत्र में किस स्तर तक समायोजित है वह इस बात पर निर्भर करता है कि उस क्षेत्र से संबंधित व्यक्ति विशेष की आवश्यकतायें कितनी सीमा तक पूरी होती हैं अथवा उनकी पूरी होने की संभावना व आशा से वह किस सीमा तक संतुष्ट रहता है, जब तक ये आवश्यकताएॅँ पूरी रहती हैं या इनकी पूर्ति की आशा उसे रहती है व्यक्ति समायोजित रहता है विपरीत अवस्था में वह कुसमायोजन का शिकार हो जाता है। अब प्रश्न यह उठता है कि व्यक्ति को अपने आप से समायोजित रखने या संतुष्ट रखने से संबंधित विभिन्न क्षेत्र कौन-कौन से हैं जिनके उपर उसका व्यक्तिगत समायोजन निर्भर करता है।
IMPACT OF COVID-19 ON MENTAL HEALTH OF ADOLESCENTS
Authors: Dubey Ruchi . , Dubey Vidhu Shekhar
Published: February 2023

The pandemic COVID-19 is a global challenge which has infected and killed peoples worldwide. Some peoples do not persist any symptom while some have fever, sore throat, cough, fatigue, weakness and muscular pain and in some cases, severe pneumonia, sepsis, acute, respiratory distress and septic shock all leading to death. It has negatively affected the economy and social integrity of countries. Along with great increase in mortality and morbidity due to this pandemic in India, COVID-19 has caused mental as well as physical health issues among general population, children, adults, elderly, migrant, workers, healthcare workers and their families. Thus, Pandemic produced by COVID-19 has a significant impact on society and has also affected children and adolescence.
IN-SERVICE TEACHER EDUCATION PROGRAMMES- AN OVERVIEW
Authors: . Nivedita , Rani Anju
Published: February 2023

As we all know that education is a never ending process that allows a person's mind to grow continuously. As a teacher, we should be able to provide the students conducive environment for better learning, as it has direct impact on students' learning. A teacher's role is very pivotal in shaping his students behavior, that's why he should never stop learning .Such things can only be achieved through continuous learning. In-service teacher education programmes provide opportunities to the in-service teachers to enhance their skills and knowledge in their respective fields. There are various platforms which are conducting in-service teacher education programmes in online and offline mode. The present paper discusses about the teacher education, in-service teacher education, its role and importance in higher education.
ALTERNATIVE EFFORTS AT CONFLICT RESOLUTION
Authors: Agashe Aparna .
Published: February 2023

Conflict management and Conflict Resolution have become one of the primary issues pervading world politics after the end of the World War II and especially after the end of the Cold War. Ethnicities have been expressing themselves freely under the newly established democratic systems. After the larger objective of the Nation State and its independence was fulfilled, the internal domestic compulsions led to the outbreak of internal rivalries that fractured communities. Although there are several methods used to bring communities together through the conflict management process like peacekeeping and peacemaking, the peace-building process is what leads us to a long-term solution to the conflict. This paper seeks to understand the significance of the peace-building process and the several alternative efforts made to bring this to fruition. All the efforts can be largely discussed under the paradigm of Restorative Justice.
शिक्षक व्यवसायिक सचोटी अभ्यास
Authors: जगताप प्रकाश .
Published: February 2023

शिक्षक हा समाजातील आणि राष्ट्र विकासातील एक महत्वाचा घटक आहे.म्हणून शिक्षक प्रमाणिक,इमानदार असणे आवश्यक आहे. आपल्या व्यवसाया विषयी ,पेशा विषयी उत्तरदायित्व ,बांधिलकी पार पाडणारे व्यक्तिमत्व शिक्षकाचे असावे.प्रस्तुत संशोधन लेखात शिक्षकाचे व्यवसायिक सचोटी ची सद्य स्थिती ,ग्रामीण व शहरी व शिक्षक शिक्षिका यांच्या व्यवसायिक सचोटीचा सर्वेक्षण संशोधन पद्धतीचा वापर करून शोध घेऊन निष्कर्ष काढले आहे.
EMERGENCE OF GENDER IDENTITY AND GENDER ROLES: A THEORETICAL ANALYSIS
Authors: . Chandrakala
Published: February 2023

The aim of this study is to identity of gender and its role in the society. Relationships between groups of women and men. An individual's concept of them, or gender identity. In this way the investigator identifies Gender socialization occurs through four major agents, family, education, peer groups, and mass media. Each agent reinforces gender roles by creating and maintaining normative expectations for gender-specific behaviour. Exposure also occurs through secondary agents, such as religion and the workplace.
ROLE OF ARTIFICIAL INTELLIGENCE IN PSYCHOLOGY
Authors: Vijaya K. .
Published: February 2023

This Article entitles that, the role of Artificial Intelligence in psychology states that Psychology is the study of mental processes and behaviour of individuals. It is about artificial cognitive processes required for an artificially intelligent entity to be intelligent, learning, autonomous and self-developing. In psychology there are several specialties or focuses of study. In cognitive psychology, how the brain thinks and works. This includes learning, memory, perception, language and Logic. There is also developmental psychology that considers how an individual adapts and changes during different developmental stages and what is appropriate to consider of a human based on development. Sports psychology considers how to affect individual performance and how performance affects the individual. So Artificial Psychology for the purposes of this paper contains the artificial mental process considered necessary to create intelligent, autonomous, self-evolving, artificially cognitive systems. “Real artificial intelligence” as the simulation of actual human behaviour is often referred to as artificial general intelligence (AGI). In AGI, machines are supposed to be built in a way that makes it impossible to distinguish them from real humans. There are three areas, in which psychology needs to play a leading role:1. User Experience (UX) in the interaction with artificial intelligence. The psychological impact of AI on humans 2. Other psychological concepts, such as emotion and empathy will have to be created in the same way as intelligence for example “Artificial Empathy” to recreate a fully functioning artificial general intelligence 3. “Mental” health of both machines and human beings.
LOAD BALANCING IN CLOUD COMPUTING
Authors: Sachdeva Meenal . , . Reena
Published: February 2023

Cloud computing has proposed a new perspective for provisioning the large-scale computing resources by using virtualization technology and a pay-per-use cost model. Load balancing is taken into account as a vital part for parallel and distributed systems. It helps cloud computing systems by improving the general performance, better computing resources utilization, energy consumption management, enhancing the cloud services’ QoS, avoiding SLA violation and maintaining system stability through distribution, controlling and managing the system workloads. In this paper we study the necessary equirements and considerations for designing and implementing a suitable load balancer for cloud environments. In addition we represent a complete survey of current proposed cloud load balancing solutions which according to our classification, They can be classified into three categories: General Algorithm-based, Architectural-based and Artificial Intelligence-based load balancing mechanisms. Finally, we propose our evaluation of these solutions based on Suitable metrics and discuss their pros and cons. Index Terms—Cloud Computing, Load Balancing, Distributed Systems, Virtual Machine.
QUALITY CONCERNS OF INDIAN EDUCATION SYSTEM- CHALLENGES AND SOLUTIONS
Authors: Kumar Sunil
Published: February 2023

The present article is an effort to throw light on the condition of education in the Indian scenario. Although 75 years have passed since independence, we still need to work hard to achieve our desired goals. A big Faculty crunch in higher education institutions is acting as a barrier in the way of providing knowledge, skill and attitude to learners. School Education is also suffering from the same situation even with basic facilities to a large section of schools. Education being in the concurrent list of the constitution also needs loyal delivery of responsibilities by state and center Governments.
THE ROLE OF CORPORATE SOCIAL RESPONSIBILITY IN WOMEN EMPOWERMENT
Authors: Achakanalli Vaishali  C.
Published: February 2023

The concept of corporate social responsibility CSR can be explained as it is an application to society that extends beyond its application towards its shareholders or owners. Today CSR is playing an important role in empowering women right from encouraging them to get education till getting a source of income. Through the present study an impact has been made to know about the various CSR activities implemented by the large scale industrial organization for women empowerment. This study also analysed the impacts of CSR activities on women empowerment and focused on the various issues encountered in the implementation of CSR programs.
NATIONAL EDUCATION POLICY 2020- SCHOOL EDUCATION
Authors: Tomar Manju  .
Published: February 2023

The NEP 2020 was approved by the Union Cabinet of India on 29 July, 2020. The Ministry of Education formed a committee headed by former ISRO Chairman Dr K Kasturirangan, who outlined the vision of India’s new education system. The New Education Policy addresses challenges faced by current education system such as Quality, Affordability, Equity, Access and Accountability. NEP 2020 envisions an India-centric education system that contributes directly to transforming our nation sustainably into an equitable and vibrant society filled by knowledge and by providing high-quality education to all. This paper is mainly focus on principles and school education
ROLE OF IMPLEMENTING AUTHORITIES UNDER POCSO ACT IN INDIA
Authors: Pratap Darekar Jyoti , Shitalabaksha Singh Vijeta
Published: February 2023

Every country needs laws for securing safety and security of its citizens. For achieving the desired outcome and for the effective implementation of these laws, there has to be an efficient machinery. There are several departments or sections whereupon different roles are assigned. More often, for implementation of one Act there could be one or more machinery required. Effectiveness and success of each Act depends on these machineries. Every person who works under any such section/department needs to be sensitized apart from his/her expertise. Since recent past whole world has noticed that there were increasing number of cases of violence committed against children. Apart from other forms of violences, children were found sexually abused too. Similarly it is seen that the offences are committed across the borders of the nation also. The National Crime records also consistently showing increasing number of criminal sexual offences committed against children. Therefore, at international level efforts have been taken and declarations were entered into. India is one of the signatory of these declarations and optional protocols. Therefore, in the year 2012, new legislation has been enacted for protecting children from sexual offences. This Act is known as The Protection of Children from Sexual Offences Act, 20121. It is clear from the title of the Act that it is in respect of protecting children from sexual offences, therefore the key functionaries apart from Government are Police, Medical officers, Courts and support persons. As one of the special feature of this Act, it has clothed some responsibilities on media, studios and also on the public. There are also some stringent provisions made for non-fulfilling the duties by these authorities. In spite of this, still number of sexual crimes committed against children is increasing day by day. Therefore, it is necessary to study about the duties assigned to these various functionaries and if there are any lacunas. Children are future of our nation and we have to do every possible efforts to provide them safe and secured environment. Therefore, it is most important to take a review about all these functionaries, as such they plays a pivotal role. Hence this topic has been selected for the research.
THEATRE IN EDUCATION – OPINION OF PROSPECTIVE TEACHERS ON EFFECTIVENESS OF THEATRE ACTIVITIES IN CLASSROOMS
Authors: K. Mohammed Sareef , P. Noushad  P.
Published: February 2023

The current education system not doing anything for understanding students or helping them in problem solving skills. It provides nothing but only a usual information package to those who pass through the gateways. It is better to diversifying the teaching strategies rather than changing the curriculum for solving this issue. The Theatre Activities which can be used in classrooms are extremely useful in this matter. The theatre has accepted a new approach for creating a bond between classroom learning and drama instruments. The major goal of this attempt is to modify the knowledge, attitude and behaviour of students. The People who have acquired sufficient training are considered as prospective teachers hence, they must be familiar with teaching strategies like Theatre Activities. It is a study conducted among prospective teachers for their opinion about the effectiveness of Theatre Activities. It includes the opinion of prospective teachers about the effectiveness and possibilities of Theatre Activities. The findings of the study reveals that most of the prospective teachers have good awareness about the learning strategies using Theatre Activities. This study reveals that it is very effective to use of Theatre Activities in the classroom for developing good relationship, leadership qualities and multiple intelligence among the students and usage of Theatre Activities are very effective for diversity in classroom and to sustain the learning interest among students.
RACIAL DISCRIMINATION SOCIAL ISSUES IN PRESENT INDIA
Authors: Ratho Rachita  Subrat
Published: February 2023

Persistent racial inequality in employment, housing, and a wide range of other social domains has renewed interest in the possible role of discrimination. And yet, unlike in the pre-civil rights era, when racial prejudice and discrimination were overt and widespread, today discrimination is less readily identifiable, posing problems for social scientific conceptualization and measurement. This article reviews the relevant literature on discrimination, with an emphasis on racial discrimination in employment, housing, credit markets, and consumer interactions. We begin by defining discrimination and discussing relevant methods of measurement. We then provide an overview of major findings from studies of discrimination in each of the four domains; and, finally, we turn to a discussion of the individual, organizational, and structural mechanisms that may underlie contemporary forms of discrimination. This discussion seeks to orient readers to some of the key debates in the study of discrimination and to provide a roadmap for those interested in building upon this long and important line of research.
maihlaa saSa@tIkrNa AaiNa AanaMdI iSaxaNaat maihlaaMcaI mah%%vaPaUNa- BaUimaka
Authors: BaihrT Saairka GaaOtma
Published: February 2023

Baart sarkarnao 2001 ho vaYa- maihlaa sabalaIkrNaacao vaYa- mhNaUna GaaoiYat kolao haoto.s~IyaaMcyaa sabalaIkrNaasaazI raYT/Iya QaaorNa The National policy for the Empowerment of women ho 2001 maQao maMjaUr krNyaat Aalao.kayado va klyaaNa kaya-k`maacyaa maaQyamaatUna Aaiqa-k‚saamaaijak‚SaOxaiNak va rajaikya yaa sava-ca xao~amaQyao maihlaaMnaa pu$YaaMcyaa baraobarInao hkk va djaa- p`dana k$na doNao ivakasaasaazI saMQaI ]plabQa k$na doNao AaiNa s~I pu$Ya Asamaanata naYT krNao yaa p`ik`yaolaa s~I saxamaIkrNa mhNatat.samaajaat maihlaaMnaa svaaya%t saxama krNyaacyaa dRYTIkaoNaatUna Anaok AiBayaana rabaivalao jaatat.pNa Krca is~yaa "Abalaa" Aahot ka ?mauLat BaartIya maihlaa kQaI Abalaa navhtIca Baart ha navadugao-caI pUjaa krNaa­yaa saMskRtItIla s~I Sa@tIcaa doSa Aaho. Kr pahta maihlaaMmaQyao inasagaa-kDUna kahI doNagyaa puR$YaaMpoxaa jaast Aahot.maihlaaMmaQyao sahnaiSalata‚navainamaa-Naxamata‚saMGap`orNaa‚saaOdMya-dRYTI‚bacat vaR%tI [%yaadI gauNa puR$YaaMpoxaa jaast Aahot.s~I hI doSaacao BaivaYya zrivaNaarI Sa@tI Aaho %yaamauLo hI Sa@tI saudRZ saxama AaiNa AanaMdI banaivaNao hI samaajaacaI jabaabadarI Aaho.
शहीद षिरोमणी तिलका माँझी
Authors: कुमार राज
Published: February 2023

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