bluuebunny/crossref_metadata_2025 huggingface dataset:
Structural Studies on the Shapeshifting Murine Norovirus
Authors: Sherman Michael B. , Williams Alexis N. , Smith Hong Q. , Pettitt B. Montgomery , Wobus Christiane E. , Smith Thomas J.
Published: October 2021

Noroviruses are responsible for almost a fifth of all cases of gastroenteritis worldwide. The calicivirus capsid is composed of 180 copies of VP1 with a molecular weight of ~58 kDa. This coat protein is divided into the N-terminus (N), the shell (S) and C-terminal protruding (P) domains. The S domain forms a shell around the viral RNA genome, while the P domains dimerize to form protrusions on the capsid surface. The P domain is subdivided into P1 and P2 subdomains, with the latter containing the binding sites for cellular receptors and neutralizing antibodies. Reviewed here are studies on murine norovirus (MNV) showing that the capsid responds to several physiologically relevant cues; bile, pH, Mg2+, and Ca2+. In the initial site of infection, the intestinal tract, high bile and metal concentrations and low pH cause two significant conformational changes: (1) the P domain contracts onto the shell domain and (2) several conformational changes within the P domain lead to enhanced receptor binding while blocking antibody neutralization. In contrast, the pH is neutral, and the concentrations of bile and metals are low in the serum. Under these conditions, the loops at the tip of the P domain are in the open conformation with the P domain floating on a linker or tether above the shell. This conformational state favors antibody binding but reduces interactions with the receptor. In this way, MNV uses metabolites and environmental cues in the intestine to optimize cellular attachment and escape antibody binding but presents a wholly different structure to the immune system in the serum. To our knowledge, this is the first example of a virus shapeshifting in this manner to escape the immune response.
Data-Driven System Dynamics Model for Simulating Water Quantity and Quality in Peri-Urban Streams
Authors: Lemaire Gregory , Carnohan Shane , Grand Stanislav , Mazel Victor , Bjerg Poul , McKnight Ursula
Published: October 2021

Holistic water quality models to support decision-making in lowland catchments with competing stakeholder perspectives are still limited. To address this gap, an integrated system dynamics model for water quantity and quality (including stream temperature, dissolved oxygen, and macronutrients) was developed. Adaptable plug-n-play modules handle the complexity (sources, pathways) related to both urban and agricultural/natural land-use features. The model was applied in a data-rich catchment to uncover key insights into the dynamics governing water quality in a peri-urban stream. Performance indicators demonstrate the model successfully captured key water quantity/quality variations and interactions (with, e.g., Nash-Sutcliff Efficiency ranging from very good to satisfactory). Model simulation and sensitivity results could then highlight the influence of stream temperature variations and enhanced heterotrophic respiration in summer, causing low dissolved oxygen levels and potentially affecting ecological quality. Probabilistic uncertainty results combined with a rich dataset show high potential for ammonium uptake in the macrophyte-dominated reach. The results further suggest phosphorus remobilization from streambed sediment could become an important diffuse nutrient source should other sources (e.g., urban effluents) be mitigated. These findings are especially important for the design of green transition solutions, where single-objective management strategies may negatively impact aquatic ecosystems.
O CORPO DA MULHER E A MOBILIDADE SOCIAL: IMPACTOS NAS MIGRAÇÕES E TRÁFICO DE MULHERES
Authors: Ferreira Serafim de Oliveira Adriana , Tuma Martins Bertolin Patrícia , Martínez Quinteiro Maria Esther
Published: October 2021

No decorrer da História da humanidade, as sociedades se acostumaram a vigiar, limitar, educar, tutelar e punir o corpo da mulher como se o ser humano feminino fosse incapaz de gerenciar sua individualidade e autonomia. A educação das subjetividades geralmente é conectada com o regime político dos Estados; contudo, em relação ao gênero feminino, além do próprio Estado, a sociedade da qual se é parte personifica o inquisidor do modo de ser e estar da mulher socialmente. Essa dinâmica social acaba perdendo intensidade em países democráticos, pois são territórios que permitem o cunho e debates quanto aos direitos fundamentais, que incluem temas sensíveis ao tecido social. O presente artigo analisou a mobilidade social do gênero feminino a partir da metade do século XX, o fenômeno do tráfico de mulheres e as migrações que podem levar a esse tipo de tráfico. Para tanto, o estudo valeu-se da revisão bibliográfica no campo das ciências humanas, sociais e jurídicas.
o IDOSO DE TEFÉ ANTE OS DIFERENTES CONTEXTOS DE VIOLÊNCIA: QUE CAMINHOS SEGUIR?
Authors: De Assis Reis Matta Betânia , Torme de Oliveira Patrícia
Published: October 2021

A violência contra o idoso é uma realidade presente no meio familiar, privado, público e social. Isso exige que os gestores públicos criem políticas públicas eficazes que visem proteger a população idosa do País. Nesse sentido, o objetivo deste artigo é discutir o papel do Estado na formulação de políticas públicas para o enfrentamento da violência sofrida por idosos, a fim de gerar reflexão sobre a temática. Trata-se de pesquisa bibliográfica realizada em artigos e livros, associada à pesquisa de campo, com abordagem qualiquantitativa, realizada nos órgãos públicos do Município de Tefé (AM): Delegacia de Polícia de Atenção ao Idoso, Secretaria Municipal de Assistência Social e Centro Municipal de Convivência da Família. A conclusão aponta que as políticas públicas de enfrentamento à violência contra idosos devem se pautar em três níveis de prevenção: primário, no sentido de prevenir a ocorrência de violência; secundário, baseado em ações com as famílias, detectando a presença de fatores de risco para os idosos; e, por fim, o terciário, com políticas que visam reduzir as consequências dos episódios de violência.
A PROTEÇÃO DOS DADOS PESSOAIS COMO NOVA ESPÉCIE DE DIREITO DA PERSONALIDADE
Authors: Ferreira dos Santos Diego
Published: October 2021

As últimas décadas foram marcadas por um espetacular avanço científico-tecnológico. Em adição, o processo de globalização potencializou o fluxo de relações sociais e econômicas entre os países, sobretudo após o advento da internet. É nesse ambiente impulsionado pela evolução tecnológica que nasce a chamada sociedade da informação. A proteção de dados pessoais surge como um potencial direito da personalidade a ser tutelado pelo direito. O problema de pesquisa recai, então, sobre quais os argumentos teóricos necessários para justificar essa nova espécie de direito personalíssimo. O objetivo é esclarecer a natureza jurídica dessa nova figura. Para responder ao problema de pesquisa, optou-se pela exploração bibliográfica de textos específicos da área e o uso predominante do método dedutivo. Ao se examinar a temática central, constatou-se que a categoria dos direitos personalíssimos não é fechada, ou seja, é possível o surgimento de novos aspectos sociais dignos de tutela legal. Ao fim, concluiu-se que o direito à proteção de dados pessoais é um novo direito da personalidade.
Using Extension as a Vehicle to Reduce Elementary Student Food Waste
Authors: Koetz Rebecca , Williams Rod
Published: October 2021

Extension can play a key role in providing food waste education nation-wide. This study is the first to evaluate the effects of environmentally focused lesson plans on elementary student knowledge and perceptions regarding food waste. Herein we provide suggestions on concepts to teach students for the greatest impact on food waste reduction. We also provide avenues to incorporate food waste education into existing Extension programming. We hope the study can inspire and inform further food waste program development, assessment, and implementation through Extension.
Implications of Delayed Reopening in Controlling the COVID-19 Surge in Southern and West-Central USA
Authors: Dandekar Raj , Wang Emma , Barbastathis George , Rackauckas Chris
Published: October 2021

In the wake of the rapid surge in the COVID-19-infected cases seen in Southern and West-Central USA in the period of June-July 2020, there is an urgent need to develop robust, data-driven models to quantify the effect which early reopening had on the infected case count increase. In particular, it is imperative to address the question: How many infected cases could have been prevented, had the worst affected states not reopened early? To address this question, we have developed a novel COVID-19 model by augmenting the classical SIR epidemiological model with a neural network module. The model decomposes the contribution of quarantine strength to the infection time series, allowing us to quantify the role of quarantine control and the associated reopening policies in the US states which showed a major surge in infections. We show that the upsurge in the infected cases seen in these states is strongly corelated with a drop in the quarantine/lockdown strength diagnosed by our model. Further, our results demonstrate that in the event of a stricter lockdown without early reopening, the number of active infected cases recorded on 14 July could have been reduced by more than

40
%

in all states considered, with the actual number of infections reduced being more than

100,000

for the states of Florida and Texas. As we continue our fight against COVID-19, our proposed model can be used as a valuable asset to simulate the effect of several reopening strategies on the infected count evolution, for any region under consideration.
Safety and efficacy of intranasal recombinant human interferon alfa 2b as prophylaxis for COVID-19 in patients on a hemodialysis program
Authors: Abdo-Cuza Anselmo , Castellanos-Gutiérrez Roberto , Treto-Ramirez Janete , Arencibia-Larin Sandra , Gómez-Pariente Thalía , González-Fernández Tania , Hernández-Perera Julio C. , Arocha-Stalella Katia , Verdecia-Gorrita Niurka , Vento-Buigues Lisy , Cordero-Vasallo Yanet , Rivero-Yi Yusmel , González-Dias Odalys , Nodarse-Cuni Hugo , Machado-Martínez Rafael , Blanco-González Miguel A. , Valdivia-Arencibia Julio , Mendez-Felipe Daymiris , Delgado-Almora Ernesto , Gutiérrez-Gutiérrez Carlos , Suárez-López Juliette , Leiva-Torres Jorge L. , Rodríguez-Sotolongo Alicia , Bejerano-Gil Nilda
Published: October 2021

Introduction: Patients diagnosed with end-stage chronic kidney disease on a hemodialysis program (HDP) represent a risk group for COVID-19. Scientific societies have developed guidelines for the prevention of contagion, but there is no prophylactic medicine in them. Objectives: To describe the safety and efficacy of recombinant intranasal human Interferon alfa 2b as prophylaxis for COVID-19 in patients in an HDP. Patients and Methods: Intervention description through the monitoring of 15 patients in outpatient HDP. Prior to the administration of the drug, clinical, radiological evaluation and hematology and blood chemistry studies were performed. Daily contact was made with each study patient in person or by telephone, asking about the occurrence of adverse events or symptoms of disease. Results: In 47% of the patients, there was leukopenia, lymphopenia in 67% and anemia and thrombocytopenia in 33% respectively, prior to the use of the drug. There was no clinical suspicion of COVID-19 in any of them. Adverse events occurred in 3 patients (20%), all were mild and non-severe. All patients were negative for SARS-CoV-2 real-time polymerase chain reaction (rtPCR) and antibody studies 45 days after the study started. Conclusion: the use of intranasal recombinant human interferon alfa 2b as prophylaxis of COVID-19 in patients in a HDP at a dose of 1 MIU daily for ten days, as part of a prevention protocol, has an adequate safety profile. None of the patients in the series was infected with SARS-CoV-2 during the surveillance period.
Impact of timing of initiation of dialysis on mortality of patients with acute kidney injury
Authors: Passoni dos Santos Reginaldo , Giroldo Vieira Letícia , Fernanda Miner de Oliveira Danielle , Fritz Schmitt Raissa , Ferreira de Barros Vinicius , Rodrigues da Silva Carvalho Ariana , Alberto Batista Peres Luis
Published: October 2021

Introduction: In Brazil, primary studies on this issue are still limited and the ideal timing of initiation of dialysis in severe acute kidney injury (AKI) still generates disagreements among experts. Objectives: To assess if the timing of initiation of dialysis is associated with the mortality of patients with AKI in intensive care unit (ICU). Patients and Methods: We retrospectively analyzed medical records of patients that developed severe AKI in the ICU. Bivariate analysis was carried out to compare data between groups of patients who underwent early dialysis (ED - initiated up to two days after the AKI diagnosis) and late dialysis (LD – initiated more than two days after the AKI diagnosis), while multivariate logistic regression was applied to identify factors associated with mortality. Results: Of the 76 patients included in the study, 27 (35.5%) were allocated in the ED group and 49 (64.5%) in the LD group. LD group had a higher frequency of sepsis [26 (53%) vs. 12 (44%); P = 0.472], while the ED group had a higher median number of dialysis sessions (6 vs. 3; P = 0.477) and higher total median time on dialysis (17.5 h vs. 13 h; P = 0.629). The overall mortality rate was 61.8% (n = 47) and of 76% (n = 22) in the ED group. The patients’ serum creatinine level at admission in the ICU was the only statistically significant risk factor for death [OR= 0.453 (95% CI= 0.257–0.801); P = 0.006]. Conclusion: The overall and in the ED group mortality rate was elevated, however, the timing of initiation of dialysis did not show statistically significant association with death. The serum creatinine at ICU admission seems to be an important mortality predictor.
Comparison of two insulin injection methods on control of type 2 diabetes; is the new protocol effective or not?
Authors: Bayani Mohammad Ali , Ghorbani Hojjatollah , Akbari Roghayeh
Published: October 2021

Introduction: Type 2 diabetes is a progressive disease with a significant risk for developing late complications. Objectives: This study aimed to determine if the discharge NPH and regular insulin doses of conventional insulin therapy protocol in which optimal glycemic control can be achieved are similar to NPH and regular insulin doses at beginning of the insulin protocol or not. In other words, we aimed to compare two insulin injection methods on the control of type 2 diabetes. Patients and Methods: This cross-sectional study was performed on hospital records of type II diabetic patients admitted for insulin therapy with the conventional protocol from 2008-2013. Treatment was initiated with the following proportions; morning NPH: 44%, morning regular dosage: 22%, evening NPH dosage: 17% and evening regular dosage: 17%. Insulin doses of the discharge day in which optimal glycemic control has been achieved were recorded and based on their mean, a protocol was made. Finally, two groups were categorized. Group 1 consisted of patients whose discharge insulin dose was in the range of the mean data of the study (±2 IU/mL) and patients whose discharge insulin dose was in accordance with the conventional protocol (±2 IU/mL) participated in group 2. Results: At discharge day, the mean morning NPH dose was 34.2±6.69, morning regular: 23.8±6.36, evening NPH: 21.26±6.75 and evening regular: 20.74±5.51. The discharge insulin ratios of the conventional protocol were similar to that of the admission ratios in only 17.7% of the patients. Only 34.5% of the patients could include in the new protocol and 50% of them didn’t fit any protocol. Conclusion: It is suggested to inject one-third of the total daily insulin need as NPH in the morning and divide the remained two-thirds between morning regular, evening NPH and evening regular equally. This may decrease the length of hospital stay and decrease the time to reach the desired glycemic control.
What about NSAID and secondary minimal change disease in adult’s people? A case report and review of the literature
Authors: Faure Erica E , Mukdsi Jorge H.
Published: October 2021

Non-steroidal anti-inflammatory drugs (NSAIDs) have been used in the management of inflammatory disease for decades. The spectrum of nephrotoxicity attributed to NSAIDs includes mainly acute tubulointerstitial nephritis. However, much less attention has been given to drug-induced glomerular injury. NSAIDs treating patients presenting with nephrotic syndrome may have a variety of glomerular changes indistinguishable from those found in idiopathic minimal change disease (MCD), for example. The clinical presentation is typically abrupt with nephrotic syndrome while in the elderly it can present as acute renal failure from the beginning. We present an MCD-NSAID induced in elderly patient and discuss possible pathogenic mechanism, thinking about on the indiscriminate use of NSAIDs. Here we report the case of a 66-year-old woman with a history of nephrotic syndrome and hypertension without an apparent secondary etiology. However, an exhaustive history showed and indiscriminate use of NSAIDs. Renal biopsy showed a MCD with a mild interstitial nephritis. To our knowledge the morphology of drug-induced diseases often does not differ from the primary forms, making the distinction difficult. There are subtle clues, although the dialogue between clinician and pathologist is essential to reach an etiological diagnosis. Physicians should suspect glomerulonephritis in patients who receive drugs and its management must be determined based on the histological characteristics of the disease. Although corticosteroid therapy seems to be of value, the effectiveness of this approach must still be tested in randomized and multicentric clinical trials.
Renal complications of sickle cell disease
Authors: Bahadoram Sara , Keikhaei Bijan , Bahadoram Mohammad , Mahmoudian-Sani Mohammad-Reza , Hassanzadeh Shakiba
Published: October 2021

The nephropathy and renal complications of sickle cell disease are associated with various events such as hypoxic or ischemic conditions and reperfusion injury. Erythrocyte sickling occurs following these events and renal medullary acidosis.
Neglected factor in the challenges of insect taxonomists: Is human attribute a barrier faced by entomologists?
Authors: Bozdoğan Hakan , Cuellar Cardozo José Alejandro
Published: October 2021

In this study, some human-oriented problems and solution proposals that insect taxonomists encounter in field studies are explained. The problems today’s modern entomologists encounter in the collection, classification, and all other field studies of insects are human-based. Moreover, these human-induced problems fall into two groups: physical and behavioral. In other words, it is necessary not to see the human footprint only as a biological and ecological diversity. In addition, the human factor also complicates the work of entomologists in terms of sensory, perceptual, and behavioral aspects.
CLINICAL PROFILE OF 2D ECHO CARDIOGRAPHY AT THE CARDIOLOGY DEPARTMENT OF CHL MULTISPECIALTY HOSPITAL AND RESEARCH CENTRE.
Authors: Mane Anil , Ainchwar Rohan , Dhanraj Ramteke Harshawardhan
Published: October 2021

Introduction:Echocardiography is the basic and important imaging technique used for the diagnosing the various numbers of Cardiac Conditions.
This helps clinicians for diagnosing a various number of clinical variations. This functional data is needed to care for patients with many
pathologies and used to diagnose a number of diseases. Trans-Thoracic Echocardiography is the most common Echocardiography done in every
Cardiology Department of Centre. The use of 2D Echo provides the proper and fast diagnosis and allows the clinicians to make further diagnosis. In
this study, we focus on Current Clinical Prole of the distributed Age Groups along with risk factors and advised recommendations with
comparison of Diagnosis.
Methods: In this case study, total of 1447 patients were divided in 6 Age Groups, proled for the outcomes of the 2D Echocardiography. We aimed
to determine the Current Clinical Prole with the Diagnosis, Risk Factors and Advised Recommendations in each age group in a Cardiac Intensive
Care Unit (CICU) in CHL Multispeciality Hospital and Research Center, Chandrapur using a prospective observational study.
Patients: All consecutive patients followed up for 2D Echocardiography at the Cardiology Department between April 2021 and August 2021 were
included if they were aged more than 18 years. Patients eligible for the study were evaluated for the current prole of the patient, risk factors and
Advised Recommendations in each Age group.
Results: In the study conducted, the clinical prole had a good result in suggesting that most of the patients in all age groups had the diagnosis of
Good biventricular systolic function, No RWMA, Normal chamber dimension & Valve function. Uncontrolled Sugars and Accelarated
Hypertension made worse for patient's cardiac management. Some Results of 2D Echo were also affected because of the emergency in the CICU,
for which 2D Echo was postponed later or after stability of the patient. Past Medical History had the signicant role. The clinical prole helped us
understand the proper diagnosis and recommendations done
COVERAGE CONSIDERATIONS AND OUTCOME ANALYSIS OF RECONSTRUCTION OF POST
TRAUMATIC SOFT TISSUE DEFECTS AROUND THE ELBOW
Authors: B Dayal Vishwamitra , Kumaran M. Senthil , Sabapathy S Raja
Published: October 2021

Introduction: Major crush injury of elbow joint following trauma with extensive injury to skin & soft tissue, bone, tendon, nerves and vessels
remains a challenge to the reconstructive surgeon. Purpose of this study is to nd out whether the size of the defect, type of ap used and the location
of the soft tissue defect inuence the outcome of soft tissue reconstruction.
Material and methods: A prospective study was performed in all patients with soft tissue defects around the elbow in need of ap cover at Ganga
Medical Centre Coimbatore, Tamilnadu India from April 2014 to December 2015.Patients demographics, defect size, location, type of ap used,
complications and long – term outcomes analysed. Patients Mayo elbow performance score and Likert scale score were recorded for analysis of
functional and aesthetic outcome respectively. The Kruskal wallis test was used for statistical comparison.
Results: Forty three aps were performed primarily for coverage in forty patients. Three patients required two primary aps for reconstruction.
The aps used in our study included 14 local fasciocutaneous aps (32.5%); 20 pedicled aps both locoregional and distant (46.5%) and 9
2 2 Anterolateral thigh free aps (20.9%) The average defect size was 151 cm . For local fasciocutaneous ap the average defect size was 44.7cm ,
2 2 2 2 2 (range, 4-120 cm ), distant pedicled ap was181 cm (range 24- 600 cm ) and for the ALT free ap was 252.2 cm (range 80-450 cm ).
Conclusion: The defect size is the main determinant of the type of ap used and their outcomes.
FACTORS ASSOCIATED WITH THE OUTCOME OF ATT AMONG HIV-TB COINFECTED PATIENTS ATTENDING THE ART CENTRE OF A TERTIARY CARE
HOSPITAL OF JHARKHAND: A PROSPECTIVE HOSPITAL BASED STUDY
Authors: Kumar Abhishek , Kumar Mithilesh , Kashyap Vivek
Published: October 2021

Background: Despite being preventable and curable, TB is the leading cause of HIV associated mortality. It is the most common opportunistic
3
infection among HIV positive individuals with CD4 cell count < 500/mm . Worldwide the number of people infected with both HIV& TB is rising.
Objectives: To assess the treatment outcome of HIV-TB Co-infected patients on Anti Tubercular treatment (ATT) attending ART Centre, RIMS,
Ranchi. Methods: It was a hospital based prospective study done at the ART centre of Rajendra Institute of Medical Sciences (RIMS), Ranchi.
Duration of study was 14 months. Atotal of 117 patients were registered during the study period and were followed up for outcome of ATT. Results:
Out of 117 patients 4 were excluded and from remaining 113 patients, treatment success was found to be 88.5%. No signicant association was
found among any of the socio-demographic variables and outcome of TB treatment. Conclusion: In this study it was concluded that sociodemographic prole had no signicant association (p>0.05) with the outcome of TB treatment and treatment success (Cured & Treatment
completed) was found in 88.5% of the HIV-TB co-infected patients
DESAIN DIDAKTIS MATERI KAIDAH PENCACAHAN UNTUK SISWA SMA KELAS XI
Authors: Jatmiko Muhammad Anang , Herman Tatang , Dahlan Jarnawi A
Published: October 2021

This study aims to develop didactic design on counting rules for senior high school. The didactic design is designed by considering two things the result of the test analysis of learning obstacle instrument and learning trajectory. This didactic design consists of four meetings obtained through the three formal stages performed in the study. The first stage is prospective ie didactic situation analysis before learning in the form of hypothetical didactic design including pedagogical didactic anticipation (ADP), second phase metaped analysis is notthe form of design implementation phase, and last stage is retrospective analysis which is an analysis that relate result of prospective analysis with metaped analysis nottik used to formulate empirik design. The research for preparing the didactic design begins with the provision of difficulties in learning the material of the counting rules and the analysis of the teaching materials. The results of the learning obstacle test show that students experience learning barriers that are categorized into three, namely ontogenic obstacle, didactical obstacle, and epistemological obstacle. The didactic design was implemented to 35 students of class XI in one of the senior high school in South Jakarta. Based on the results of research, didactic design developed this can be used as an alternative teaching materials concept of counting rules to minimize student learning barriers.
ANALISIS KESANTUNAN BERBAHASA MAHASISWA UNIVERSITAS BINA SARANA INFORMATIKA DALAM BERINTERAKSI DENGAN DOSEN MELALUI PESAN SINGKAT WHATSAPP: KAJIAN PRAGMATIK
Authors: Parancika Rd Bily , Setyawan Erwin
Published: October 2021

The more younger lecturers among young students, the more they would like to approach them, either during lecture or outside the class. The approach might make the relationship between lecturers and students closer and more emotional. However, it could seem less politeness which students have. This can be seen from the way and the language use through text messages on social medias, particularly on WhatsApp. This research aims to find out the variety of the students' politeness when having interaction with lecturers trough short message on WhatsApp by describing the students' language politeness, the principles of the deviation in politeness, the obedience and the function of the language politeness itself in the relationship between students and lecturers of Universitas Bina Sarana Informatika. Primary data in this research is written conversation records, especially screen shots of chats on WhatsApp. Secondary data is the  knowledge of Pragmatic Studies of Bahasa Indonesia including the theories regarding language politeness principles in order to impact to the characters of the nation's next generation. The method used in this research is pragmatic studies, in particular with pragmatic and contextual equivalents.
Cervical lymph node metastasis revealing a prostate adenocarcinoma: About two observations and Review of the Literature
Authors: Sylvain DIembi  , Boris Harold Otouana Dzon  , Gérard Chidrel Ngouoni  , Franck Arnaud Itiere OdzilI  , Synclair Ngotene Diembi  , Donatien Moukassa  , Gontran Ondzotto
Published: October 2021

Prostatic adenocarcinoma is the most common cancer in men, and is the 3rd leading cause of death in men worldwide. This slow-growing, hormone-sensitive cancer occurs after the age of 50 years. Cervical lymph node metastases of prostate adenocarcinoma are rare. We report two anatomical observations over a ten-year period of activity. The two men were aged 80 and 72 years, respectively, and both presented with multiple cervical adenopathies of particular topography above the clavicle, associated with urinary signs such as dysuria, pollakiuria and incontinence. Microscopic examination coupled with immunohistochemistry (anti-PSA antibodies) of the excised biopsy of these lymph nodes contributed to the diagnosis of certainty.

Keywords: Adenocarcinoma; Prostate; Metastasis; Node; Neck; Immunohistochemistry
Mathematical model of excitation-contraction in a uterine smooth muscle cell
Authors: Ai Weiwei , Freifeld Limor , Nickerson David
Published: October 2021

The Bursztyn et al. (2007) paper proposes a mathematical model of excitation-contraction in a myometrial smooth muscle cell (SMC). The model incorporates processes of intracellular Ca^2+ concentration control, myosin light chain (MLC) phosphorylation and stress production. We create a modularized CellML implementation of the model, which is able to simulate these processes against the original data.
PROBLEMS OF FINANCING OF AGRICULTURAL EXTENSION ACTIVITIES IN UKRAINE
Authors: POKHYLENKO Nataliia , KORINETS Roman
Published: October 2021

The article analyzes the current state of financial support for socially oriented extension services in Ukraine in order to identify the obstacles to stability and regularity of its implementation. It has been established on the basis of statistical data, that the financing of such activities from the state budget has a downward trend. Its volumes are tens of thousands of times less than similar budgetary expenditures in post-socialist countries that are currently EU members. The results of a survey of representatives of consulting services showed that the reason for the low activity of the registered agricultural extension services in the implementation of state programs to support agricultural producers and, accordingly, the incomplete development of the allocated funds are the scarcity, unpredictability and instability of state support for agricultural extension activities, the weakness of the coherence between themselves of the state programs, aimed at the development of the agricultural sector of economy. There is also a lack of understanding of the importance of agricultural extension by local government representatives. It is proved that conservatism in the introduction of innovations by owners of small farms, low level of awareness of agricultural extension, significant distance of advisory centers from potential customers, low income of the rural population minimize their ability to pay for commercial advisory services. It is established that financial and organizational difficulties have a significant negative impact on the psychological aspects of counseling. Advisors declare a lack of faith in their own strength. The results of the study allow us to assert that the formation of stable, simple and clear rules for long term state financing of agricultural extension activities and the absolute abidance of such rules by state institutions will help to increase the sustainability of financial support for agricultural extension activities in Ukraine.
ACCOUNTING SUPPORT FOR MANAGEMENT OF COSTS FOR PRODUCTION AND SALE OF GARDENING PRODUCTS
Authors: PRAVDIUK Nataliia
Published: October 2021

The current state and development trends of the horticultural industry, highlights the problematic aspects in the activities of enterprises in the current economic conditions, outlines the prospects for their development, the costs of the production of fruit and berry products and the profitability of enterprises in the horticultural industry were analyzed in the article. It has been established that our country has a significant climatic and economic potential for obtaining high yields of products of the horticultural industry, however, due to the existence of systemic economic imbalances and gaps in sectoral policy, there is a decrease in the production of fruit and berry products, the lack of satisfaction of the needs of the domestic market for high-quality products of its own production and increase in imports of fruits and berries. It is substantiated that in order to solve the problems that have developed in the industry, it is necessary to take a number of organizational, economic, technical and technological solutions aimed at the effective use of available resources, the introduction of resource-saving technologies, the rational use of the bioclimatic and economic potential of the country. On the basis of a study of the sectoral features of the activity of horticultural enterprises, it was found that business entities bear significant costs for storing finished products in fruit storages in connection with the expectation of a favorable conjuncture of the agricultural products market. Due that the costs of storage and transportation of finished products are accounted for as part of sales costs, together with other expenses of the period are subject to write-off at the end of the period to determine financial results, difficulties arise with the accurate calculation of selling prices for finished products, which can negatively affect the levels profitability of enterprises. In order to mitigate this risk, it is proposed, within the framework of management accounting, to distribute sales costs and other expenses of the period among certain types of finished products in proportion to their production cost, which creates the preconditions for accurate calculation of selling prices for fruit and berry products, balanced implementation of pricing policy by business entities and effective management of the marketing costs of enterprises.
Communication in a pandemic: Concerns of agricultural and natural resources opinion leaders during early stages of the COVID-19 pandemic
Authors: Baker Lauri , Chiarelli Christy , Rampold Shelli , McLeod-Morin Ashley , Lindsey Angela
Published: October 2021

During the early stages of the COVID-19 pandemic (March-April 2020), opinion leaders in agriculture and natural resources (ANR) were asked to participate in a survey about the impacts of the crisis on the ANR industry specifically about their concerns related to communication, economics, level of preparedness, and health during this crisis. Of the 225 ANR leaders who participated, the majority were concerned that members of the public were sharing inaccurate information about COVID-19; others they come into contact with were not taking appropriate measures to avoid contracting COVID-19; about the impact of COVID-19 on the U.S. economy, their state’s economy, and the global economy; and other countries’ level of preparedness to deal with COVID-19. ANR leaders were consistently the most concerned about items that were outside of their direct sphere of influence. Implications from this work are that ANR leadership programs should incorporate programing to help ANR leaders understand how to be influential during a crisis at a national and international level. For statewide ANR leadership programs, it is recommended to include programming sessions related to identifying and sharing credible information and enabling and inspiring those in their circle of influence to do the same.
Identifying important skills and competencies needed for new Florida agriculture extension agents
Authors: Halbritter Alicia , Wallau Marcelo , Benge Matt , Mackowiak Cheryl
Published: October 2021

The onboarding needs of Extension agents is a topic continuously discussed and researched, yet overwhelmed agents persist, suggesting that there is still a missing link. We undertook a study to determine the competency training needs of newly hired agricultural agents in Florida. Two assessments were performed. First, we asked University of Florida’s County Extension agents and Directors in Agriculture, Horticulture and Natural Resources to identify main agriculture skills and competencies for new Extension. Second, we then classified those competencies into main domains and asked the same cohort to rank the competencies within each domain, in order of most important to least important. Data were collected via an online surveys, with 65% and 51% response rates, respectively. Agents needed training in specific agricultural competencies related to every-day work activities such as soil sampling, diagnostic skills, educational resource utilization, and relationship building. Although we assume that, based on job requirements, newly hired agents will enter Extension with such knowledge, results suggest an agriculture specific training is needed to meet the onboarding needs of new agents. Our study identified the priority needs for developing an onboarding program that establishes a level of standard knowledge. Those findings will serve to enhance onboarding training for new Extension professionals.
Preservice agriculture teachers’ perceived self-efficacy of specific SAE competencies
Authors: Rubenstein Eric , Scott James
Published: October 2021

With the implementation of the supervised agricultural experience (SAE) within school-based agricultural education (SBAE), hands-on learning has changed how students learn in the classroom. SAE programs, a key component of agricultural education, are an example of experiential learning within the SBAE model. The implementation of SAE experiences has been often viewed as difficult for many teachers, and many new agricultural educators struggle with implementing SAE into their classroom instruction. Therefore, this study sought to determine the self-efficacy of preservice agriculture teachers towards the American Association for Agricultural Education-Supervised Agricultural Experience (AAAE) SAE competencies. Results indicated that a majority of preservice teachers considered SAE an important aspect of the SBAE model. However, results indicated that few competencies showed significant differences between pre- and post-completion of the agricultural program, and gender differences did not indicate much significance in self-efficacy. Data indicates that teacher preparation programs have been successful in preparing students to develop, implement, and supervise SAE programs during student teaching. The researchers recommend that further research should examine additional agricultural teacher preparation programs and determine the self-efficacy of cooperating teachers in the classroom.
GIS in the gas supply system for monitoring, control and prevention of emergencies
Authors: Pivovarova I
Published: October 2021

The article discusses the possibilities of GIS technologies for the presentation of a gas pipeline network in electronic form for the purpose of effective management, as well as technological and environmental monitoring of facilities. Examples of technogenic cataclysms that occurred due to the lack of integration of spatial information systems with existing control systems are given. The tools of domestic and foreign GIS used by IT departments of companies in the energy complex are described.
Strategic planning documents in the system of ensuring the national security of the Russian Federation: theoretical and legal aspect
Authors: Iroshnikov D
Published: October 2021

The question of the regulatory impact of strategic planning documents and their place among the sources of Russian law is investigated. The functions of strategic planning documents that characterize their role as a legal means of ensuring national security are defined. The analysis of the evolution of strategic planning documents in the field of national security is carried out, on the basis of which the trends of their transformation are identified.
Regulating the Deformation Properties of Paper by Varying the Degree of Its Anisotropy
Authors:   Techpap SAS, B.P. 251, Rech Didier , Potasheva Anastasiia N. ,   Northern (Arctic) Federal University named after M.V. Lomonosov, Kazakov Yakov V.
Published: October 2021

Mechanical properties are crucial in assessing the paper quality. Deformation and strength properties of paper are determined by the strength and stiffness of the interfiber and intermolecular hydrogen bonds. The contribution ratio of interfiber and intermolecular hydrogen bonds to the strength of paper can be changed by adjusting the degree of its anisotropy. The article presents the results on a study of the deformation properties of laboratory anisotropic paper samples from kraft bleached softwood pulp with a beating degree of 30 °SR. The samples had basic weight of 90 g/m2 and the degree of stiffness anisotropy TSIMD/CD of 1.75–4.08. They were made by using Techpap SAS automatic dynamic handsheet former (Grenoble, France), with varying forming parameters – diameter of the nozzle, motion speed of the forming wire, and injecting speed of pulp. Deformation properties were determined by tensile test and processing of the stress-strain dependence (σ−ε). The outcomes have shown that, an increase of the fiber orientation degree in paper structure by changing the forming parameters caused a change in the nature of the paper deformation under tension. Increasing the fiber orientation degree in the structure of paper made it possible to increase the strength by 55 %, tensile stiffness by 63 % in the machine direction, while reducing the extensibility by 10 %. In the cross direction, it was possible to decrease tensile stiffness by 33 %, strength by 55 %, and increase the extensibility by 5 %. Anisotropy of tensile strength was 1.73–6.00. The greatest effect was obtained for the elasticity modulus in the pre-failure zone E2 (2.8–38.6). It means that, fiber orientation had a key importance when large deformations in the samples took place. The established quantitative regularities allowed optimizing the values of the deformation and strength properties of paper, and their ratio in the machine direction and cross direction due to the variation of the forming parameters. For citation: Rech D., Potasheva A.N., Kazakov Ya.V. Regulating the Deformation Properties of Paper by Varying the Degree of Its Anisotropy. Lesnoy Zhurnal [Russian Forestry Journal], 2021, no. 5, pp. 174–184. DOI: 10.37482/0536-1036-2021-5-174-184
Scots Pine (Pinus sylvestrisL.) Undergrowth on the Dumps of the Chrysotile Asbestos Deposit
Authors:   Ural State Forest Engineering University, Zaripov Yuriy V. , Zalesov Sergey V. , Zalesova Evgeniia S. , Popov Artem S. , Platonov Evgeniy P. , Starodubtseva Natal’ya I.
Published: October 2021

The studies were carried out on the dumps of overburden rocks and tailings of poor ores of the chrysotile asbestos deposit. According to the scheme of forest site zoning, the studying area belongs to the pre-forest steppe district of pine and birch forests of the Zabaikal’ye plain province of the West Siberian plain forest site area. The survey sites were laid out on the terraces of the dump along the running lines. Undergrowth was counted at each survey site. It was classified by viability, size (small, medium, large), and life form (tree, bush, scrub). The provision with undergrowth of the indicated type of disturbed soils was defined and recommendations for measures aimed at accelerating the process of reforestation were given. Undergrowth on the dumps is represented by Scots pine (Pinus sylvestris L.), silver birch (Betula pendula Roth.), aspen (Populus tremula L.), and goat willow (Salix caprea L.). Scots pine and silver birch are the dominant species in the undergrowth composition. Large share of Scots pine of scrub and bush form is the specific feature of the developing young growth. These specimens were found among small- and medium-sized undergrowth. It is the undergrowth of these heights that becomes an annual attrition without passing into the large-sized category. The latter is the main reason for faster conversion of the dumps into forest-covered area, for increasing the share of clay particles in the upper 50 cm thick dump layer, or for coating the dump surface by non-traditional fertilizers, in particular sewage sludge. It was noted that silvicultural trend in the dump reclamation on the chrysotile asbestos deposit is the most preferable. Scots pine should be preferred as the primary species for reclamation planning. For citation: Zaripov Yu.V., Zalesov S.V., Zalesova E.S., Popov A.S., Platonov E.P., Starodubtseva N.I. Scots Pine (Pinus sylvestris L.) Undergrowth on the Dumps of the Chrysotile Asbestos Deposit. Lesnoy Zhurnal [Russian Forestry Journal], 2021, no. 5, pp. 22–33. DOI: 10.37482/0536-1036-2021-5-22-33
De Quervain’s Disease among Motorcycle Repair Mechanics and Related Factors
Authors: Iwan Muhamad Ramdan  , Adriani Nur  , Muhammad Sultan  , Ratno Adrianto  , Irfansyah Baharudin
Published: October 2021

Introduction: Work-musculoskeletal disease is still an occupational health problem worldwide that needs to be investigated in every different type of work.Objectives: Identify De Quervain’s disease (DQD) prevalence on motorcycle repair mechanics and it’s risk factors. Methods: A cross-sectional study on 60 motorcycle repair mechanic in Samarinda city of Indonesia. To determine DQD, a Finkelsteins test was performed. Age, education background, working period, working time per day, and frequency of repetitive motion of the mechanic were collected by direct interview. The number of samples using the Lemeshow formula. Phi coefficient test is applied to identify the correlation between DQS prevalence and other parameters. Results: the DQD prevalence of 63.3% was found, occurred in right and left hands, 36 and 24%, respectively. It correlates significantly with age (p=0.047, r=0.346), working period (p=0.000, r=0.861), education background (p=0.045, r=0.367), working time per day (p=0.055, r=0.616), and frequency of repetitive motion (p=0.004, r=0.374). Conclusions:The prevalence of DQD in motorcycle repair mechanics is quite high and requires attention, prevention and control from stakeholders so that the prevalence does not increase.
Anthropometry Measures and Prevalence of Obesity among Undergraduates of Public University Libya
Authors: Nazeh laater  , Mohamed A. M. Alhoot  , Osama B, Albajalan
Published: October 2021

This research examines demographics, socioeconomic, eating habits, andphysical activity on obesity prevalence in students of Libya. The present study population consists of undergraduate students joining the universities of the west coast of Libya. Specifically, the research has been carried out with undergraduate students of two public universities (Zawia University and Sabaratha University) of Libya. The present study has used a survey based on the constructs of the conceptual framework. Therefore, self-distributed questionnaires for each of 500 samples of the student to collect from the questionnaire.This research has done a comprehensive theoretical discussion to be able to come up with the research hypotheses. The hypotheses were that there is a significant relationship between demographic factors and obesity prevalence in undergraduate students of Libya. Also, there is no significant relationship between socioeconomic factors and obesity prevalence in undergraduate students of Libya and.Furthermore, there is a significant difference between male and female undergraduate students in terms of eating habits. And finally, there is a significant difference between male and female undergraduate students in physical activity.Moreover, the study proposes the management take the initiative for the implementation of strategies that will be helpful to get the awareness about obesity among students in Libya.