bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH FORMULA DAN PERBANDINGAN BUMBU SERBUK DENGAN SANTAN SERBUK TERHADAP KARAKTERISTIK BUMBU GULAI SERBUK DENGAN METODE FOAM-MAT DRYING
Authors: Suliasih Neneng , Nurminabari Ina Siti
Published: March 2018

Tujuan dari penelitian ini adalah untuk mempelajari formula dan perbandingan bumbu serbuk dengan santan serbuk dalam pembuatan bumbu gulai serbuk dengan menggunakan metode foam-mat drying, sehingga diperoleh karakteristik yang baik yang dapat di manfaatkan untuk bumbu masakan gulai. Penelitian dilakukan dengan menggunakan Rancangan Acak Kelompok (RAK) yang terdiri dari 2 faktor A (Formula) yang terdiri dari 2 taraf yaitu a1 (formula 1), dan a2 (formula 2) dan faktor B (perbandingan bumbu serbuk dengan santan serbuk) yang terdiri dari 3 taraf yaitu b1 (1 : 1,5), b2 (1 : 1), dan b3 (1,5 : 1). Respon dalam penelitian adalah respon organoleptik (warna, aroma, dan rasa), respon kimia (kadar air dan kadar lemak), dan respon fisik (uji kadar rendemen). Berdasarkan hasil penelitian, diketahui bahwa formula berpengaruh terhadap warna, aroma, dan kadar lemak, perbandingan bumbu serbuk dengan santan serbuk berpengaruh terhadap warna, aroma, rasa, kadar air, dan kadar lemak serta interaksi antara formula dan perbandingan bumbu serbuk dengan santan serbuk berpengaruh terhadap aroma, rasa dan kadar lemak. Perlakuan terpilih yaitu produk bumbu gulai dengan menggunakan formula 2 (a2) dan perbandingan bumbu serbuk dengan santan serbuk (1,5 : 1) (b3) yang memiliki kadar air 10,88%, kadar lemak 10,97% dan kadar rendemen rata-rata untuk formula 2 (a2) sebesar 28,41%.
Evaluation of the clinical effects of diet and physical rehabilitation in dogs following tibial plateau leveling osteotomy
Authors: Baltzer Wendy I. , Smith-Ostrin Sarah , Warnock Jennifer J. , Ruaux Craig G.
Published: March 2018

OBJECTIVE To assess clinical effects of an omega-3 fatty acid and protein-enriched diet, physical rehabilitation, or both in dogs following tibial plateau leveling osteotomy (TPLO) and arthroscopic surgery for cranial cruciate ligament (CCL) disease.

DESIGN Randomized, prospective clinical trial.

ANIMALS 48 dogs with unilateral CCL disease.

PROCEDURES Dogs were randomly assigned to receive a dry omega-3 fatty acid and protein-enriched dog food formulated to support joint health (test food [TF]), a dry food formulated for maintenance of adult dogs (control food [CF]), TF plus rehabilitation (TF-R), or CF plus rehabilitation (CF-R). Data collected over 6 months included body weight, body condition score, ground reaction force data, tibial plateau angle, limb circumference measurements, subjective pain and lameness scores assigned by surgeons and dog owners, and daily activity measured by accelerometry.

RESULTS Peak vertical force and vertical impulse were greater after surgery for dogs in the TF groups than in the CF groups; peak vertical force was greater after surgery in dogs that underwent rehabilitation than in those that did not. Owner scores indicated lower frequencies of lameness and signs of pain during some activities for the TF group, compared with other groups, and for the TF-R and CF-R groups, compared with the CF group. Sedentary time decreased and time spent in light-to-moderate or vigorous activity increased in all groups over time. Rehabilitation was significantly associated with greater time spent in light-to-moderate activity, regardless of diet.

CONCLUSIONS AND CLINICAL RELEVANCE Feeding the TF and providing physical rehabilitation during the first 6 months after TPLO were associated with improvements in some indices of clinical outcome and function in dogs. Significant interactions between time and some outcome variables were observed, indicating further research is warranted.
Survival analysis to evaluate associations between periodontal disease and the risk of development of chronic azotemic kidney disease in cats evaluated at primary care veterinary hospitals
Authors: Trevejo Rosalie T. , Lefebvre Sandra L. , Yang Mingyin , Rhoads Catherine , Goldstein Gary , Lund Elizabeth M.
Published: March 2018

OBJECTIVE To examine potential associations between periodontal disease (PD) and the risk of development of chronic azotemic kidney disease (CKD) among cats and determine whether the risk of CKD increases with severity of PD.

DESIGN Retrospective cohort study.

ANIMALS 169, 242 cats.

PROCEDURES Cats were evaluated ≥ 3 times at any of 829 hospitals from January 1, 2002, through June 30, 2013. Cats with an initial diagnosis of PD of any stage (n = 56,414) were frequency matched with cats that had no history or evidence of PD (112,828) by age and year of study entry. Data on signalment, PD, and other conditions potentially related to CKD were extracted from electronic medical records. Cox proportional hazards modeling was used to estimate the association of PD with CKD after controlling for covariates.

RESULTS PD was associated with increased risk of CKD; risk was highest for cats with stage 3 or 4 PD. Risk of CKD increased with age. Purebred cats had greater risk of CKD than mixed-breed cats. General anesthesia within the year before study exit and diagnosis of cystitis at any point prior to study exit (including prior to study entry) were each associated with increased CKD risk. Diagnosis of diabetes mellitus or hepatic lipidosis at any point prior to study exit was associated with decreased CKD risk.

CONCLUSIONS AND CLINICAL RELEVANCE The findings supported the benefit of maintaining good oral health and can be useful to veterinarians for educating owners on the importance of preventing PD in cats.
AUTEKOLOGI BEGONIA DI SEBAGIAN KAWASAN TAMAN NASIONAL GUNUNG MERAPI
Authors: Undaharta NKE. , Sutomo Sutomo
Published: March 2018

Penelitian dilakukan pada bulan September 2013 di Taman Nasional Gunung Merapi, Yogyakarta dengantujuan untuk mengetahui data ekologi Begonia di habitat alaminya serta tumbuhan bawah yang ada di sekitarnya.Pengambilan sampel dilakukan dengan membuat plot ukuran 2 x 2 m secara purposive sampling. Data lingkunganyang diperoleh masing-masing plot pada habitat Begonia dianalisis menggunakan Canonical CorespondenceAnalysis (CCA) dengan program Canoco untuk mengetahui seberapa besar pengaruh faktor-faktor ini terhadapkeberadaan Begonia. Data kelimpahan (abudance) vegetasi ditabulasikan ke dalam format excel spreadsheet yangdiinput ke dalam software PRIMER. Data dilakukan pre-treatment dengan square root transformation kemudian dihitung matriks kemiripan atau resemblance matrix berdasarkan indeks kemiripan Bray-Curtis sebagai dasar analisis Non Metric Multidimensional Scaling ordination/NMDS untuk mengetahui sebaran kelimpahan Begonia.Sebanyak 3 jenis Begonia yang dapat ditemukan di sebagian kawasan Taman Nasional Merapi diantaranya Begoniamultangula Blume, B. hirtella Link dan B. tenuifolia Draynd. Begonia hanya dijumpai di Bukit Plawangan danBukit Pranajiwa. Tumbuh secara mengelompok pada ketinggian 1004-1164 m dpl. Tumbuh pada kemiringan lahan27-40%, pH tanah 6.6-6.9, kelembaban tanah 10-19%. Begonia memiliki preferensi asosiasi dengan ketinggiantempat dan kelembaban tanah. Sumbu altitude lebih signifikan berperan dalam distribusi Begonia di lokasi studidibandingkan sumbu lingkungan kelembaban tanah. Hasil penelitian ini diharapkan dapat memberikan informasiyang bermanfaat dalam melakukan aklimatisasi dan konservasi Begonia.
BLOOD GLUCOSE LEVEL AND PANCREAS HISTOLOGICAL SECTION OF MICE ( Mus musculus L.) INDUCED BY ALLOXAN AFTER TREATMENT OF Curcuma mangga Val. RHIZOME EXTRACT
Authors: Madihah Madihah , Alfina Fitriani , Gani Yetti Yusri
Published: March 2018

Herbal-based drug development for diabetes mellitus continues to grow in order to find alternatives of theuse of synthetic drugs which is relatively expensive. The present study examined the potency of temu mangga(Curcuma mangga Val.) rhizome extract in decreasing blood glucose levels and repairing histological damage ofpancreas endocrine gland in male mice (Mus musculus L.) Swiss-Webster that has been induced by alloxan. Theexperimental method with 5 treatments and 5 replications were used. The dose of alloxan was 200 mg/kg bw,while the dose of temu mangga extract were 100, 200, 400 and 800 mg/kg bw. The measured parameters werethe body weight, fasting blood glucose levels by using blood glucose tolerance test, and the percentage of pancreatic? cells that undergo necrosis. Data were analyzed by ANOVA with 95% confidence level and continued withDuncan’s multiple range tests. The results showed no difference on body weight of test animals in all treatments.The reduction percentage of fasting blood glucose levels from temu mangga rhizome extract by dosage of 400mg/kg bw (48.712%) was significantly different from the treatment of alloxan (0.588%) (p<0.05). The percentageof ? cells that undergo necrosis from temu mangga rhizome by dosages of 200, 400, and 800 mg/kg bw weresignificantly different with alloxan (22.75±3.68 %) (p<0.05). In conclusion, temu mangga rhizome extract bydosage of 400 mg/kg was optimum to decrease blood glucose levels and repair the pancreas histological damagein mice that were induced by alloxan.
Impacts of Macronutrients on Gene Expression: Recent Evidence to Understand Productive and Reproductive Performance of Livestock
Authors: Sohel Md. Mahmodul Hasan , Konca Yusuf , Ulas Cinar Mehmet
Published: March 2018

In order to identify the effects of nutrients on gene expression and to assess the interactions between genes and nutrition by means of various cutting-edge technologies, the interdisciplinary branch ‘Nutrigenomics’ was created. Therefore, nutrigenomics corresponds to the use of knowledge and techniques of nutrition, genomics, transcriptomics, proteomics, epigenomics, and metabolomics to seek and explain the cross-talk between nutrition and genes in molecular level. Macronutrients are important dietary signals that control metabolic programming of cells and have important roles in maintaining cellular homeostasis by influencing specific gene expression. Recent advancements in molecular genetics studies, for instance, use of next-generation sequencing, microarray and qPCR array to investigate the expression of transcripts, genes, and miRNAs, has a crucial impact on understanding and quantitative measurement of the impact of dietary macronutrients on gene function. This review will shade a light on the interactions and mechanisms how the dietary source of macronutrients changes the expression of specific mRNA and miRNA. Furthermore, it will highlight the exciting recent findings in relation to animal performance characteristics which eventually help us to identify a dietary target to improve animal production.
Communication: Photoinduced Carbon Dioxide Binding with Surface-Functionalized Silicon Quantum Dots
Authors: Douglas-Gallardo Oscar A. , Sánchez Cristián Gabriel , Vöhringer-Martinez Esteban
Published: March 2018

Nowadays, the search of efficient methods able to reduce the high atmospheric carbon dioxide concentration has turned into a very dynamic research area. Several environmental problems have been closely associated with the high atmospheric level of this greenhouse gas. Here, a novel system based on the use of surface-functionalized silicon quantum dots (sf -SiQDs) is theoretically proposed as a versatile device to bind carbon dioxide. Within this approach, carbon dioxide trapping is modulated by a photoinduced charge redistribution between the capping molecule and the silicon quantum dots (SiQDs). Chemical and electronic properties of the proposed SiQDs have been studied with Density Functional Theory (DFT) and Density Functional Tight-Binding (DFTB) approach along with a Time-Dependent model based on the DFTB (TD-DFTB) framework. To the best of our knowledge, this is the first report that proposes and explores the potential application of a versatile and friendly device based on the use of sf -SiQDs for photochemically activated carbon dioxide fixation.
A Surface Plasmon Resonance Based Inhibition Immunoassay for Sensitive and Selective Detection of 17β-Estradiol
Authors: Cao Yong , McDermott Mark T.
Published: March 2018

Quantitative measurement of small-molecule metabolites is now emerging as an effective way to link the metabolite profile to disease state. Surface plasmon resonance (SPR) is a sensing platform that has demonstrated applicability for a large range of biomolecules. However, direct detection of small molecules with SPR challenges the refractive index based detection mechanism. Herein, we utilized an indirect detection format and developed an inhibition immunoassay for the quantitative measurement of 17β-estradiol (E2) using SPR. One competitor, BSA-E2 conjugate, was immobilized to the SPR chip via the reaction between the primary amino group of the conjugate and the succinimide group (NHS) introduced by the formation of a thiol-NHS monolayer on gold surface. Free E2 molecules compete with BSA-E2 on chip surface for binding sites provided by a monoclonal anti-E2 antibody. It was found the binding affinity of the antibody to BSA-E2 conjugate increases with decreasing surface coverage of BSA-E2 conjugate. Under optimal conditions, a sigmoidal calibration curve with a negative slope and a dynamic range from 10 pM to 2 nM was generated. The detection limit of the immunoassay is estimated to be 0.3 pM. Moreover, the immunoassay exhibits high specificity for E2 detection using estrone (E1) as a potential interference.
Bio-composite materials: a short review of recent trends, mechanical and chemical properties, and applications
Authors: YILDIZHAN Şafak , ÇALIK Ahmet , ÖZCANLI Mustafa , SERİN Hasan
Published: March 2018

Recently, the
attraction on the bio-composite (known as green composites) materials has
significantly increased due to the potential of being substitute to
conventional materials used in manufacturing industries. Bio-composite
materials are produced with natural fibres or natural resins instead of
synthesized fibres (carbon, glass, etc fibres) or resins (poly vinyl alcohol, epoxy,
etc resins ). The bio-based fibres such as jute, sisal, flax, hemp, bamboo,
hair, wool, silk etc., are obtained from plants or animals. Also, natural matrix
materials such as natural rubber, polyester, etc., are produced from plants.
The advantages of bio-composites such as the ease of disposal and being able to
composted characteristics of bio-composites after the expiration date which is
not generally possible with conventional synthetic materials, being renewable,
sustainable  have attracted many  researcher. Furthermore, the comparable
mechanical properties of bio-composites make feasible for application to many
different products. This study reviews the, recent trends, mechanical and
chemical properties, and application of bio-composites in recent years.
Educación, maestro y ciudadaní­a en el Bolí­var Grande (Colombia), 1870-1889: variables de una continuidad
Authors: Salas Martínez Luisinho Eder
Published: March 2018

A partir del análisis de las fuentes oficiales e instruccionistas que circularon en el Bolí­var Grande, en este trabajo se hace una reflexión en torno a la continuidad histórica entre el liberalismo radical y la Regeneración en Colombia. Se consideran tres elementos centrales: la preocupación por la educación pública, el papel de las escuelas de primeras letras, las normales en la formación de ciudadanos modernos y, por último, la representación del maestro de escuela como modelo de ciudadano "ideal". Estas lí­neas se inscriben en la tendencia contemporánea de los estudios en América Latina sobre educación, ciudadaní­a y nación; en particular, sobre las distintas herramientas que utilizan los nacientes estados para la alineación del ciudadano y en las que la escuela, a partir del maestro, desempeña un papel esencial.
TÜRKİYE’NİN KREDİ NOTUNU ETKİLEYEN FAKTÖRLERİN MARS YÖNTEMİ İLE BELİRLENMESİ
Authors: Yuksel Serhat , Özsarı Mustafa
Published: March 2018

Bu çalışmanın
amacı Türkiye kredi notuna etki eden makroekonomik faktörlerin belirlenmesidir.
Bu bağlamda, ülkenin kredi notuna etki edebilecek 8 adet değişken inceleme
kapsamına alınmıştır. Belirtilen amaca ulaşabilmek için söz konusu değişkenlere
ait 1992 ve 2015 dönem aralığındaki yıllık veriler MARS yöntemi kullanılarak
test edilmiştir. Elde edilen analiz sonuçlarına göre, ülkenin cari işlemler
dengesi ile kredi derecelendirme notu arasında pozitif yönlü bir ilişki
bulunduğu belirlenmiştir. Başka bir ifadeyle, cari işlemler açığının GSYİH
rakamına oranı arttıkça, Türkiye’nin kredi derecelendirme notunun azaldığı tespit
edilmiştir. Belirtilen hususlar dikkate alındığında, kredi derecelendirme
notunun artması için Türkiye’nin ilk olarak cari işlemler açığı problemini
çözmeye odaklanması yerinde olacaktır.
Alteridade e produção de gênero na poética de diva cunha: matéria ardente, vida e arte
Authors: De Sousa Ilza Matias
Published: March 2018

ResumoA questão da literatura feminina no Brasil assinala uma pluralização textual, que permite conceber a experiência poética de Diva Cunha como escritura heterogênea e espaço de resistência do outro. A desconstrução de sentidos instituídos instaura uma nova imagem da mulher numa rede de caminhos e formas de representação de alteridade.Palavas-chaveEscritura. Alteridade. Gênero. Poesia.
KECENDERUNGAN PEMILIHAN TOPIK DAN ANALISIS KESALAHAN PENULISAN JUDUL ESAI MAHASISWA JURUSAN ILMU HUKUM UNIVERSITAS ISLAM SULTAN AGUNG (SEBUAH KAJIAN MKU BAHASA INDONESIA)
Authors: Arsanti Meilan
Published: March 2018

Method used in this research was documentation of students� assignments. Result of the research indicated that students of Law Science department in Unissula preferred topics related to social problems, 28.12% of total 12 topics for 64 students. The rest topics were 7.81% about politics and government, 15.62% of�corruption, 7.81% of health, 17.18% of education, 1.56% of economics, 28.12% of social, 0% of art and culture, 10.93% of law, 0% of technology, 0% of sports, and 7.81% of environment. Result of error analysis in writing essay title represented in a bar chart indicated that the errors were 10.93% on capital letter, 4.68% on words, 12.50% on words which are included as conjunctions (linking words), and 3.12% on punctuation. In the aspects of italic words writing, prepositions, repeated words and interjections (feeling exclamations), the errors were 0%. Total�error was about 31.23% while the correct writing was 68.77%. Thus, it indicated that students of Law Science department, who mostly known to attach to legal issues, preferred to social topics happened in Indonesia. It was because they were freshmen who did not focus on legal issues yet. Social issues are often sensitive to legal issues. In writing essay title, the errors mostly done by students of Law Science department of Unissula were on conjunctions writing, such as using capital letters on conjunctions which should be written with small letters. Besides, the errors mostly happened when the students used capital letters on words which should be written in small letters.
PENINGKATAN KEMAMPUAN MENULIS TEKS BERITA DENGAN MODEL THINK PAIR AND SHARE (TPS) MENGGUNAKAN MEDIA VISUAL PADA SISWA KELAS VIII SMPN 3 SAYUNG DEMAK
Authors: Magfiroh Anik , Turahmat Turahmat , Wardani Oktarina Puspita
Published: March 2018

Penelitian ini menggunakan desain penelitian tindakan kelas (PTK) dengantiga siklus, yaitu siklus I, siklus II, dan siklus III dengan batas ketuntasanminimal 71. Setiap siklus terdiri dari empat tahap yaitu perencanaan,pelaksanaan, observasi, dan refleksi. Subjek dalam penelitian adalahketerampilan menulis teks berita pada siswa kelas VIII SMP N 3 SayungDemak. Teknik pengumpulan data menggunakan teknik tes dan nontes.Teknik tes berupa menulis teks berita dan teknik nontes berupa, observasi,angket, wawancara, dan dokumentasi. Analisis data meliputi data kuantitatifdan data kualitatif. Peningkatan hasil tes siswa dapat dilihat dari hasil tespada siklus I mendapatkan nilai rata-rata 73,33, siklus II mendapatkan nilairata-rata 79,30, dan siklus III mendapatkan nilai rata-rata 91,03. Sehinggaterjadi peningkatan dari siklus II sebesar 5,97, dan siklus III sebesar 11,73Hasil nontes observasi sikap, siklus I siswa mendapatkan rata-rata sikapbaik, siklus II siswa mendapatkan rata-rata sikap baik, dan siklus III siswamendapatkan rata-rata sikap baik sekali. Angket sikap prasiklusmendapatkan siklus I mendapatkan nilai rata-rata 83,37%, siklus IImendapatkan nilai rata-rata 87,54%, dan siklus III mendapatkan nilai ratarata99,62%. Angket motivasi siklus I mendapatkan nilai rata-rata 66,7%,siklus II mendapatkan nilai rata-rata 72,16%, dan siklus III mendapatkannilai rata-rata 79,7%.
Hambur Balik Akustik Permukaan Substrat Dasar Perairan Menggunakan Echosounder Bim Tunggal
Authors: Hamuna Baigo , Dimara Lisiard , Pujiyati Sri , N. Natih Nyoman Metta N.
Published: March 2018

Penelitian ini bertujuan untuk menganalisis nilai hambur balik permukaan dasar perairan berupa pasir dan lumpur. Echosounder bim tunggal Simrad EK15 frekuensi 200 kHz digunakan untuk perekaman hambur balik akustik permukaan dasar perairan. Pengambilan data dilakukan pada bulan tanggal 29 April – 2 Mei 2017 yang berlokasi di perairan Teluk Yos Sudarso, Kota Jayapura Provinsi Papua. Pengambilan contoh substrat digunakan untuk data validasi menggunakan sedimen grab. Hasil penelitian ini menggambarkan nilai rata-rata hambur balik permukaan substrat perairan pasir bervariasi antara -37.48 dB sampai -36.03 dB, dan lumpur bervariasi antara -46.98 dB sampai -45.15 dB. Hal ini juga menunjukkan bahwa substrat pasir memiliki tingkat kekerasan dan ukuran butir yang lebih besar dibandingkan jenis substrat lumpur substrat. Secara akustik, nilai hambur balik permukaan pasir akan lebih tinggi dibandingkan lumpur
Danau Laut Balbullol di Misool Raja Ampat
Authors: Purba Gandi YS , Haryono Eko , Sunarto Sunarto
Published: March 2018

Danau laut adalah ekosistem unik yang ditemukan terfokus di empat lokasi saja di dunia. Salah satunya di Raja Ampat. Danau-danau tersebut memiliki karakter yang unik sesuai tingkat koneksinya dengan laut. Danau Balbullol adalah danau yang paling dalam diantara danau laut di Misool, terasing, dan belum pernah dikaji. Melalui studi ini ingin mengetahui karakter dari Danau Balbullol. Deskripsi danau dilakukan dengan serangkaian survei lapangan dan perekaman logger untuk mengetahui karakter fisik, kualitas air, dan kehadiran biota. Hasilnya diketahui luas danau adalah 1,94 ha dengan kedalaman maksimum 38 m. Suhu dan salinitas memperlihatkan profil vertikal yang homogen, sehingga membentuk tipe holomiktik. Selama 6 bulan time series dari rekaman logger, menunjukan suhu di danau selalu lebih panas dari pada di laut, demikian juga salinitas yang lebih salin di danau. Pasut di danau tertunda 4 jam daripada laut, walaupun jarak antara danau dan laut sangat dekat (<45 m). Amplitudo pasut hanya 25% daripada laut. Walaupun dari hasil pengukuran pasut Danau Balbullol merupakan danau yang terisolasi, namun tidak ditemukan biota sebagai indikator danau terisolasi. Ditemukan minimal 7 karang lunak dengan atribut banyak dan melimpah di danau ini.
Impact of organizational factors on delays in BIM-based coordination from a decision-making view: a case study
Authors: JANG Sejun , LEE Ghang
Published: March 2018

This study analyzed the impact of organizational factors on delays in building information modeling (BIM)- based coordination for mechanical, electrical, and plumbing (MEP) systems from the decision-making perspective. Recently BIM-based coordination has been regarded as a critical phase in project delivery but suffers from delays during the coordination process. This study investigated three complexity factors that often contribute to coordination delays: the number of participants – the total number of participants involved in a decision-making process for resolving a coordination issue; the level of the decision makers – the highest decision-maker involved in a problem-resolution process; and the heterogeneity of participants –the number of trades related to an issue. Using 95 major coordination issues derived from 11,808 clashes in a case study, the correlations between the coordination time and the complexity factors were analyzed. The coordination time linearly increased as each factor increased. The number of participants had the highest correlation with the coordination time, followed by the level of decision makers and the heterogeneity of participants. The findings stress the significance of integration between BIM and lean approaches, such as Obeya (big room) and Shojinka (flexible manpower line), during BIM-based coordination to expedite decision-making processes and eventually to reduce the coordination time.
Surface Composition of (99942) Apophis
Authors: Reddy Vishnu , Sanchez Juan A. , Furfaro Roberto , Binzel Richard P. , Burbine Thomas H. , Le Corre Lucille , Hardersen Paul S. , Bottke William F. , Brozovic Marina
Published: March 2018

On 2029 April 13, near-Earth asteroid (NEA) (99942) Apophis will pass at a distance of ∼6 Earth radii from Earth. This event will provide researchers with a unique opportunity to study the effects of tidal forces experienced by an asteroid during a close encounter with a terrestrial planet. Binzel et al. predicted that close flybys of terrestrial planets by NEAs would cause resurfacing of their regolith due to seismic shaking. In this work, we present the best pre-encounter near-infrared spectra of Apophis obtained so far. These new data were obtained during the 2013 apparition using the NASA Infrared Telescope Facility (IRTF). We found that our spectral data is consistent with previous observations by Binzel et al. but with a much higher signal-to-noise ratio. Spectral band parameters were extracted from the spectra and were used to determine the composition of the asteroid. Using a naïve Bayes classifier, we computed the likelihood of Apophis being an LL chondrite to be >99% based on mol% of Fa versus Fs. Using the same method, we estimated a probability of 89% for Apophis being an LL chondrite based on ol/(ol+px) and Fs. The results from the dynamical model indicate that the most likely source region for Apophis is the ν
6 resonance in the inner main belt. Data presented in this study (especially Band I depth) could serve as a baseline to verify seismic shaking during the 2029 encounter.
Multiple-component Decomposition from Millimeter Single-channel Data
Authors: Rodríguez-Montoya Iván , Sánchez-Argüelles David , Aretxaga Itziar , Bertone Emanuele , Chávez-Dagostino Miguel , Hughes David H. , Montaña Alfredo , Wilson Grant W. , Zeballos Milagros
Published: March 2018

We present an implementation of a blind source separation algorithm to remove foregrounds off millimeter surveys made by single-channel instruments. In order to make possible such a decomposition over single-wavelength data, we generate levels of artificial redundancy, then perform a blind decomposition, calibrate the resulting maps, and lastly measure physical information. We simulate the reduction pipeline using mock data: atmospheric fluctuations, extended astrophysical foregrounds, and point-like sources, but we apply the same methodology to the Aztronomical Thermal Emission Camera/ASTE survey of the Great Observatories Origins Deep Survey–South (GOODS-S). In both applications, our technique robustly decomposes redundant maps into their underlying components, reducing flux bias, improving signal-to-noise ratio, and minimizing information loss. In particular, GOODS-S is decomposed into four independent physical components: one of them is the already-known map of point sources, two are atmospheric and systematic foregrounds, and the fourth component is an extended emission that can be interpreted as the confusion background of faint sources.
Testing Off the Clock: Allowing Extended Time for All Students on Tests
Authors: Birkhead Susan F.
Published: March 2018

Background:

Standardized time allotments are typically imposed for administration of nursing tests. There is little evidence to guide the determination of time allotment. When time allotted for tests is too limited, construct irrelevant variance in test scores may be introduced and the reliability of tests may be negatively impacted.

Method:

For test administration, we establish a standard time allotment and offer all students the option of extended time.

Results:

Many of the students use extended time, reporting that extended time reduces stress. Program outcomes have not been negatively affected. Data are provided to guide calculation of time allotment.

Conclusion:

Extended time may help relieve test anxiety and facilitate success for students with undiagnosed learning disabilities or non-native English speakers. Time allotment should be based on the item composition of tests using published mean item response times. Further research is needed. [
J Nurs Educ.
2018;57(3):166–169.]
Escape Room Recruitment Event: Description and Lessons Learned
Authors: Connelly Liane , Burbach Beth E. , Kennedy Colleen , Walters Lisa
Published: March 2018

Background:

The U.S. nursing workforce is facing a severe shortage of professionals due to an anticipated retirement of more than 500,000 RNs in the next 5 years.

Method:

An Escape to Nursing event was created and delivered in a rural medical center college of nursing in the spring of 2017. This faculty team developed four distinct rooms that were designed with key nursing concepts and patient health conditions. Recruits worked in teams to solve the patient health care puzzle, which then enabled them to proceed to the next room.

Results:

Feedback was positive from the recruits, including comments about expanding the game to more health care scenarios and reaching out to more recruits. Additional recruitment may lead to better turnout of recruits.

Conclusion:

Linear, sequential formatting for the escape room game design is recommended for use with recruits into nursing. The use of escape rooms for recruitment is a positive activity. [
J Nurs Educ.
2018;57(3):184–187.]
Pregnancy and the Opioid Epidemic
Authors: Haycraft Amy L.
Published: March 2018

Opioid use disorder (OUD) in pregnancy is increasing, which often results in poor maternal and neonatal outcomes including neonatal abstinence syndrome (NAS) as a result of lack of prenatal care and inadequate substance use disorder management. Practice guidelines have been developed to manage OUD during and after pregnancy for mother and baby, but barriers exist, limiting comprehensive implementation. To reduce the impact of OUD in pregnancy and associated maternal and neonatal sequela, implementing compassionate evidence-based care and a non-punitive response is needed. A stigma-free approach, substance use disorder screening, medication-assisted treatment, screening and treatment of mental health disorders, and an after-birth environment that promotes maternal–child bonding are recommended. [
Journal of Psychosocial Nursing and Mental Health Services, 56
(3), 19–23.]
Automatic Generation of Children's Songs Based on Machine Statistic Learning
Authors: Pan Li
Published: March 2018

In this paper, the automatic generation of children's songs is studied. First of all, according to the number of key lyrics submitted by the songwriter, statistical machine learning is used to expand and obtain more theme-related lyrics, and then the first sentence is generated through the language model automatically. On this basis, the subsequent sentences are generated through the statistical machine learning translation method. In the process of the generation, the statistical machine learning is used to expand the conception of the song, so as to get richer sentence candidates. The main features and contributions of the study are: Firstly, the statistical machine learning translation is put forward as the theoretical basis, the preceding and next sentence relationship of children's songs are mapped into the relation of the source language and target language in the statistical translation model, and the machine statistics learning translation model is designed with the integration of the domain knowledge of songs. Secondly, the statistical machine learning is used in the generation process to expand the lyrics words, thereby enhancing the theme and conception of the song. The experimental results have confirmed the effectiveness of the proposed method.
Multi-objective Optimization Algorithm for Multimedia English Teaching (MOAMET) Based on Computer Network Traffic Prediction Model
Authors: Feng Wei Wei
Published: March 2018

In order to solve the problem of multi-objective optimization for multimedia English teaching, this paper proposes a multi-objective optimization algorithm for multimedia English teaching (MOAMET) based on computer network traffic prediction model, which is based on the computer network traffic prediction model strategy. This algorithm establishes time series for individuals correlated to same reference points, and for such time series through computer network traffic model optimizes multimedia English teaching objectives. Meanwhile, it feeds back the prediction error of the historical moment to the current prediction to improve the accuracy of the optimization, and adds disturbance in each optimized individual to increase the diversity of initial multimedia English teaching so as to speed up the convergence speed of the algorithm in the new environment. Through experiments it teats the algorithm, also makes comparison and analysis with two existing algorithms, the results show that the proposed algorithm can maintain good performance in dealing with multi-objective optimization for multimedia English teaching.
Comparison of the Features of EPUB E-Book and SCORM E-Learning Content Model
Authors: Chang Hsuan-Pu , Hung Jason C.
Published: March 2018

E-books nowadays have greatly evolved in its presentation and functions, however its features for education need to be investigated and inspired because people who are accustomed to using printed books may consider and approach it in the same way as they do printed ones. Therefore, the authors compared the EPUB e-book content model with the SCORM e-learning content model from the respects of their content presentation, metadata and package structures. Drs. Chang and Hung found that 1) EPUB has the possibility to implement the advantage of content sharing and reusing. 2) EPUB e-books can present educational materials with multimedia and interactive components based on web technology. However, content creators should beware of the limited supported media types 3) EPUB lacks dedicated educational metadata. 4) EPUB e-books have a content reflow mechanism to adjust layouts to fit small screen devices and are able to use all resources offline. Finally, they determined the research issues and strategies that are worthy of further investigation and development for EPUB e-books in education based on our findings.
IT-Driven Business Model Innovation
Authors: Müller Sune , Hundahl Mads
Published: March 2018

Information technology enables disruptive innovations, causing paradigm shifts in how companies do business. IT allows companies to break with traditional business models and management thinking. This article explores IT-driven business model innovations empirically by examining how 343 Danish companies use IT to innovate their existing businesses. This systematic review of extant literature using the Business Model Canvas as an analytical framework to answer the research question; how does IT drive business model innovation? Through an exploratory factor analysis this article observes the underlying structure of IT-driven business model innovation, identifying three innovation sources: customers, infrastructures, and supply chains. The three sources demonstrate where and how innovation is most likely to occur, and how it may spread to other parts of the business model. This paper presents a framework for understanding the impact of IT on business models, providing researchers and practitioners with empirically based knowledge on how to leverage IT for business model innovation.
Developing a Public Online Learning Environment for Crisis Awareness, Preparation, and Response
Authors: Bacon Liz , MacKinnon Lachlan M , Flippoupolitis Avgoustinos , Kananda David
Published: March 2018

This article describes the design and development of an online immersive learning environment focused on enhancing the general public's awareness of, and preparation for, crisis situations. This research has sought to answer the question “Is it possible to develop a timeline based immersive and engaging training environment for mass self-study education in crisis preparedness?” The system developed is based on the Pandora+ training environment and integrates original collaborative European research work carried out on eLearning and Crisis Management over the last ten years. The research reported here not only describes the design of the Pandora+ training environment but also the outputs from a pilot trial in Lisbon run by the POP-ALERT EU FP7 project. Where appropriate, the results were also compared to those from a large EU survey on crisis preparedness and attitudes, also undertaken within POP-ALERT. The results of this article have resulted in an original and innovative system that has significant potential to transform the education of the public in disaster preparedness.
Pictographs in Disaster Communication for Linguistically Challenged and Illiterate Populations
Authors: Frommberger Lutz , Waidyanatha Nuwan
Published: March 2018

This article describes how pictographs (or pictograms) can be an important means to communicate information about natural disasters to people that are lacking the capability to understand written text. This does not only include illiterates, but also foreigners not speaking the local language. While it is widely accepted that pictograph-based communication can play a major role, there is no established workflow to include this kind of symbols in early warning or disaster reporting practice. This article investigates the topic of pictograph-based communication systems, especially in the field of natural disasters, with a focus on the use of linguistically challenged populations. The authors analyze existing literature, take a look at existing pictograph resources, analyze a first field study with marginalized populations and derive conclusions for a design process for pictograph-based disaster communication systems.
Bertrand Oligopoly Competition in Composite Web Service Network
Authors: Wang Yu , Liang Xinle , Xu Rui , Liu Chuang , Chen Huaping
Published: March 2018

Because of its heterogeneous nature, a web service can be composed of multiple composite web services. To improve profitability in the software-component economy, software as a service (SaaS) service providers compete more at the composite-service level than at the single-service level. Moreover, because of the collaborative environment, composite web service networks determine both the applicability of the web service and its expected economic behavior. Based on the traditional linear demand model, this article presents a congestion-aware demand model that makes several assumptions regarding the SaaS service marketplace. Then, it formulates the SaaS service providers' pricing behaviors as a network Bertrand oligopoly competition. Key game-theoretic analysis includes the existence and uniqueness of the pure strategy Nash equilibrium. Moreover, this article provides one sufficient condition, where if all SaaS service providers follow the best response strategy, the strategy profile converges to the unique pure strategy Nash equilibrium.
RGC32 Promotes Bleomycin-Induced Systemic Sclerosis in a Murine Disease Model by Modulating Classically Activated Macrophage Function
Authors: Sun Chenming , Chen Shi-You
Published: March 2018

Systemic sclerosis (SSc) is a multisystem autoimmune disorder that is characterized by inflammation and fibrosis in the skin and internal organs. Previous studies indicate that inflammatory cells and cytokines play essential roles in the pathogenesis of SSc; however, the mechanisms that underlie the inflammation-driven development of SSc are not fully understood. In this study, we show that response gene to complement 32 (RGC32) is abundantly expressed in mouse macrophages in the early stage of bleomycin-induced SSc. Importantly, RGC32 is required to induce the inflammatory response during the onset of SSc, because RGC32 deficiency in mice significantly ameliorates skin and lung sclerosis and inhibits the expression of inflammatory mediators inducible NO synthase (iNOS) and IL-1β in macrophages. RGC32 appears to be a novel regulator for the differentiation of classically activated macrophages (M1 macrophages). IFN-γ and LPS stimulation induces RGC32 expression in primary peritoneal macrophages and bone marrow–derived macrophages. RGC32 deficiency impairs the polarization of M1 macrophages and attenuates iNOS and IL-1β production. Mechanistically, RGC32 interacts with NF-κB proteins and promotes iNOS and IL-1β expression by binding to their promoters. Collectively, our data reveal that RGC32 promotes the onset of SSc by regulating the inflammatory response of M1 macrophages, and it may serve as a promising therapeutic target for treating SSc.
MTOR Suppresses Cigarette Smoke–Induced Epithelial Cell Death and Airway Inflammation in Chronic Obstructive Pulmonary Disease
Authors: Wang Yong , Liu Juan , Zhou Jie-Sen , Huang Hua-Qiong , Li Zhou-Yang , Xu Xu-Chen , Lai Tian-Wen , Hu Yue , Zhou Hong-Bin , Chen Hai-Pin , Ying Song-Min , Li Wen , Shen Hua-Hao , Chen Zhi-Hua
Published: March 2018

Airway epithelial cell death and inflammation are pathological features of chronic obstructive pulmonary disease (COPD). Mechanistic target of rapamycin (MTOR) is involved in inflammation and multiple cellular processes, e.g., autophagy and apoptosis, but little is known about its function in COPD pathogenesis. In this article, we illustrate how MTOR regulates cigarette smoke (CS)–induced cell death, airway inflammation, and emphysema. Expression of MTOR was significantly decreased and its suppressive signaling protein, tuberous sclerosis 2 (TSC2), was increased in the airway epithelium of human COPD and in mouse lungs with chronic CS exposure. In human bronchial epithelial cells, CS extract (CSE) activated TSC2, inhibited MTOR, and induced autophagy. The TSC2–MTOR axis orchestrated CSE-induced autophagy, apoptosis, and necroptosis in human bronchial epithelial cells; all of which cooperatively regulated CSE-induced inflammatory cytokines IL-6 and IL-8 through the NF-κB pathway. Mice with a specific knockdown of Mtor in bronchial or alveolar epithelial cells exhibited significantly augmented airway inflammation and airspace enlargement in response to CS exposure, accompanied with enhanced levels of autophagy, apoptosis, and necroptosis in the lungs. Taken together, these data demonstrate that MTOR suppresses CS-induced inflammation and emphysema—likely through modulation of autophagy, apoptosis, and necroptosis—and thus suggest that activation of MTOR may represent a novel therapeutic strategy for COPD.
Boundedness of moduli of varieties of general type
Authors: Hacon Christopher D. , McKernan James , Xu Chenyang
Published: March 2018

We show that the family of semi log canonical pairs with ample log canonical class and with fixed volume is bounded.
Caracterización mecánica y reológica de un hormigón autocompactante elaborado con finos de recuperación procedentes de la fabricación de mezclas asfálticas
Authors: Castillo Mingorance Juan Manuel , Martínez-Echevarría Romero María José , Rodríguez Montero José , López Alonso Mónica
Published: March 2018

En el trabajo que se presenta, se estudia la valorización de un fíller de recuperación, procedente de plantas de fabricación de aglomerados asfálticos, para su uso en la elaboración de hormigones autocompactantes (HAC) con aplicaciones estructurales. En primer lugar, se ha caracterizado el fíller para determinar su aplicabilidad en este tipo de hormigones. Posteriormente se han diseñado hormigones autocompactantes con los requisitos que exige su aplicación estructural en una clase IIb de exposición ambiental. Se ha partido del método de dosificación de Okamura, modificando las proporciones hasta seleccionar, mediante su ajuste con amasadas de prueba, la dosificación más conveniente que cumpla los requisitos normalizados de autocompactabilidad. Una vez logradas las propiedades de autocompactabilidad, el trabajo se ha centrado en la evaluación de las características mecánicas del hormigón seleccionado, determinando, entre otras, las resistencias a compresión y tracción, el módulo de deformación, el coeficiente de Poisson y la fluencia. Como referencia, se ha elaborado otro HAC, con la misma dosificación que el seleccionado pero empleando en su confección un fíller comercial, con el fin de evaluar los efectos del fíller objeto de estudio. Finalmente se estudia el comportamiento de las armaduras embebidas en el seno de este hormigón mediante la determinación del contenido crítico de cloruros que provocaría una corrosión intolerable. Los resultados obtenidos hasta la fecha están indicando que el hormigón elaborado con el fíller de recuperación satisface plenamente los requisitos de autocompactabilidad exigidos por la normativa actual, si bien exige una mayor dosis de aditivo superplastificante para lograrla. Asimismo este hormigón ha alcanzado valores de resistencia superiores a los mínimos establecidos para su aplicación estructural, sin embargo, se han observado en él mayores deformaciones instantáneas y a largo plazo que en el hormigón de referencia. El umbral de cloruros determinado, cuyo valor ha resultado ser ligeramente superior al establecido para hormigones convencionales,  permite predecir un  comportamiento satisfactorio de este HAC frente a la corrosión del acero de las barras corrugadas.DOI:http://dx.doi.org/10.4995/HAC2018.2018.5320
Desarrollo de hormigones autocompactables de resistencia media (HAC-RM) en Colombia
Authors: De La Cruz Morales Claudia Jenny , Tamayo Galeano Andrés Felipe
Published: March 2018

Los resultados obtenidos con el uso del HAC a nivel mundial, ha arrojado resultados convincentes para el empleo del mismo, evidenciando que es una alternativa que genera seguridad, eficiencia, rapidez y mejor ambiente de trabajo, proporcionando una economía significativa de diferentes formas, dentro del proceso constructivo.La construcción civil en Colombia, exige la implementación de nuevas tecnologías eficientes y es así como los HAC de Resistencia Media-Baja (HAC-RM), se convierte en la primera herramienta que garantiza un hormigón fluido (H.F) sin problemas de segregación o exudación y principalmente por sus propiedades en estado fresco, las cuales son determinadas en el laboratorio y en obra, por medio de una serie de ensayos diseñados para tales fines, cuyos resultados permiten caracterizar cuantitativamente y cualitativamente la propuesta e implementación del nuevo HAC-RM en Colombia, siguiendo la metodología propuesta por De La Cruz (2006) [1] y aplicada ya en Medellín para algunos trabajos docentes y de grado, en el Laboratorio de Estructuras (LABEST) de la Facultad de Minas de la Universidad Nacional de Colombia (UNAL).DOI: http://dx.doi.org/10.4995/HAC2018.2018.5548