bluuebunny/crossref_metadata_2025 huggingface dataset:
Modelo clasificador para personalizar ejercicios propuestos a estudiantes utilizando redes neuronales artificiales
Authors: Saire Peralta Edwar Abril , Velarde Allazo Edwar Andrés
Published: January 2023

El artículo tiene como objetivo el desarrollo de un modelo que permite predecir en forma personalizada los ejercicios que puede resolver un estudiante, y por otro lado los que no puede resolver. El modelo está basado en una serie de factores que influye en los ritmos de aprendizaje de los estudiantes. El curso que se utilizó como experimento en el proyecto es el manejo de funciones en hojas de cálculo. Para el desarrollo del proceso se ha utilizado la metodología de minería de datos KDD (Knowledge Discovery in Databases) y para el modelo se ha utilizado redes neuronales artificiales con aprendizaje hacia atrás (Backpropagation), el cual es un algoritmo de aprendizaje supervisado. El modelo se alimenta con datos como sexo, edad, grado académico, nivel de instrucción de los padres, tipo de colegio, calificaciones previas de los temas que el estudiante obtiene mientras avanza en el curso. El enfoque de la investigación es de corte cuantitativo, experimental, de tipo aplicada y la población estuvo representada por 85 estudiantes. El resultado muestra que el modelo logra una probabilidad del 72% de precisión al predecir la asignación de ejercicios a los estudiantes según sus características. Los ejercicios que no pueden ser resueltos se les anexa una ayuda para su mejor comprensión y resolución.
Enseñanza recíproca influenciado por los niveles de alfabetización informacional en estudiantes de Ciencias de la Comunicación
Authors: Ocrospoma Guillermo , Fuster-Guillén Doris , Ocaña-Fernández Yolvi , Villalba-Condori Klinge Orlando
Published: January 2023

Introducción: el actual desarrollo tecnológico trasciende toda actividad humana, como la educación. Analizando la vinculación de competencias digitales logradas por los estudiantes, aplicados a métodos de enseñanza colaborativos, establecimos la relación existente entre competencias de alfabetización informacional (AI) y enseñanza recíproca (ER) en estudiantes de Ciencias de Comunicación; basada en la clasificación de competencias de AI en DigComp 2.1 relacionadas con habilidades y actitudes promovidas por la ER.

Método: la investigación fue anonimizada, se utilizó un cuestionario digital con 100 preguntas de AI y 22 preguntas de ER, ambas con escala de Likert con valores de 0-9; la fiabilidad del instrumento validado mediante Alfa de Cronbach con valores de .987 para AI y .992 para ER, así como la revisión a juicio de 3 expertos.

Resultados: los datos mostraron una distribución no normal, aplicando Rho de Spearman se determinó que existe relación significativa, estableciendo mediante Regresión Logística Multinomial que la AI de nivel N3 predomina, concentrando el 90% de casos, reflejado en los 2/3 de ER concentrados en niveles Bajo-Medio, los coeficientes de regresión evidencian que el bajo desarrollo de AI no conducen a un ER avanzado.

Conclusiones: en Perú, el desarrollo de las Competencias Digitales, fundamentalmente las 3 dimensiones de AI (navegar, evaluar y gestionar información), es semejante a España, siendo que, evaluarla debe tener mayor desarrollo para lograr que los comunicadores puedan combatir las fake news, un nivel N3 sería insuficiente, se necesitaría una revisión de la curricula universitaria y mejorar la formación estudiantil para lograrlo, porque ser “nativos digitales” no basta.
PENGARUH STRUKTUR MODAL, PEMBIAYAAN JUAL BELI DAN PEMBIAYAAN BAGI HASIL TERHADAP PROFITABILITAS PADA BANK UMUM SYARIAH YANG TERDAFTAR DI BANK INDONESIA
Authors: Hasbi Hartas
Published: January 2023

Penelitian ini bertujuan untuk menganalisis pengaruh struktur modal pembiayaan jual beli dan pembiayaan bagi hasil terhadap profitabilitas pada bank umum syariah di Indonesia. Data yang digunakan adalah data sekunder. Populasi dalam penelitian ini adalah 11 Bank Umum Syariah di Indonesia. Teknik sampling yang digunakan adalah purposive sampling dengan kriteria Bank Umum Syariah di Indonesia yang menyajikan laporan keuangan periode 2012-2015. Terdapat 2 sampel Bank Umum Syariah yang layak digunakan yaitu Bank Negara Indonesia dan Bank Syariah Mandiri. Data yang dikumpulkan diolah dengan menggunakan analisis regresi berganda dengan bantuan SPSS versi 22. Hasil dari penelitian ini menunjukkan bahwa : (1) Struktur modal mempunyai pengaruh negatif dan signifikan terhadap profitabilitas pada bank umum syariah di Indonesia. (2) Pembiayaan jual beli mempunyai pengaruh negatif dan signifikan terhadap profitabilitas pada bank umum syariah di Indonesia. (3) Pembiayaan bagi hasil mempunyai pengaruh positif dan signifikan terhadap profitabilitas pada bank umum syariah di Indonesia.
PENGARUH CAPITAL ADEQUACY RATIO (CAR) DAN MUDHARABAH TERHADAP RETURN ON ASSET (ROA) PADA BANK UMUM SYARIAH YANG TERDAFTAR DI OTORITAS JASA KEUANGAN (OJK)
Authors: Irawan Besse Khadijah , Sapitri Niluh Anik
Published: January 2023

This study aimed (1) to determine the effect of the capital adequacy ratio on return on assets at Islamic Commercial Banks registered with Otoritas Jasa Keuangan (Financial Services Authority ((OJK), (2) to investigate the effect of mudharabah return on assets at Islamic Commercial Banks registered with OJK, and (3) to find out the effect of the capital adequacy ratio and mudharabah return on assets at Islamic Commercial Banks registered with OJK. This reserach was conducted from July to August 2021. The type of research conducted was quantitative descriptive with an associative approach. The data source used was secondary data. The population used covered all financil statements of Islamic Commercial Banks (ICB) in Indonesia registered with OJK  for the  2016-2020 period. The sampling technique used was the saturated sampling technique. The data was obtainedfrom times series of financial reports with a total of 60 samples. Observation and documentation were used as techniques in collecting data. The data analysis method used was multiple linear regression The results of this indicate that (1) partially, the capital adequacy ratio had a positive and significant effect on retun on assets at Islamic Commercial Banks (2) partially, mudharabah had no significant effect on return on assets at Islamic Commercial Banks, and (3) simulatneously, the capital adequacy ratio and mudharabah had a positive and significant effect on the return on assets of Islamic Commercial Banks. Based on the results of the research above, the capital adequacy ratio and  mudharabah have a substantial influence on return on assets at Islamic Commercial Banks registered with OJK. Therefore, the bank can supervise and maintain the quality of the capital adequacy ratio and mudharabah on ROA in increasing the profit of the bank. The implication shows that both variables of capital adequacy ratio and mudharabahhave a good influence on return on assets because they have a positive impact or can manage to increase bank profit.
PENGARUH DIFERENSIASI PRODUK WESEL POS TERHADAP PELAYANAN PADA PT POS INDONESIA (Studi Pada Kantor Pos Watampone)
Authors: Jasgunawan Andi , Keri Ismail
Published: January 2023

Skripsi ini membahas mengenai Pengaruh Diferensiasi Produk Wesel Pos Terhadap Pelayanan Pada PT Pos Indonesia. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh diferensiasi produk wesel pos terhadap pelayanan dan seberapa besar pengaruh diferensiasi produk wesel pos terhadap pelayanan pada Kantor Pos Watampone. Metode yang digunakan dalam penelitian ini yaitu pendekatan kuantiatif dengan populasi yang diperoleh sebanyak 190 sehingga menghasilkan 66 sampel yang merupakan konsumen wesel pos dengan menggunakan rumus slovin. Teknik pengumpulan data yaitu kuesioner, observasi dan dokumentasi. Analisis data yang digunakan yaitu regresi linear sederhana dengan program SPSS Versi 20. Hasil penelitian ini menunjukkan bahwa diferensiasi produk berpengaruh signifikan dan positif terhadap pelayanan dengan koefisien sebesar 0,706. Dari pengujian koefisien determinasi diketahui 70,6% menunjukkan bahwa diferensiasi produk memiliki pengaruh terhadap pelayanan. Sedangkan sisanya 29,4% dipengaruhi oleh faktor atau variabel lain yang tidak diketahui atau tidak termasuk dalam analisis regresi ini.
MEKANISME PEMBUKAAN DAN PENUTUPAN REKENING TABUNGAN PADA ANAK USIA DINI DI BANK SYARIAH(Studi pada PT Bank Muamalat Kabupaten Bone)
Authors: Masyhuri Masyhuri , Putri Juliandari
Published: January 2023

A bank is a financial institution whose main business is to raise funds, distribute funds, and provide services in payment traffic and money circulation. Islamic banking as an institution that collects and distributes funds has various types of businesses that offer various conveniences for the public to meet the needs of business capital, consumptive needs, future savings, and just meet entertainment needs. Mechanism is a process of carrying out an activity carried out by a person or several people using orders and rules as well as the flow of communication and division of tasks in accordance with professionalism. This study aims to find out how the mechanism for opening and closing savings accounts in early childhood in Islamic banks, and to find out how savings law in early childhood is in an Islamic economic perspective. Based on the purpose of the study, this research is a type of qualitative research using a grounded theory approach. This technique is used to describe the data that researchers collect, both data from interviews, observations and documentation during research at "PT. Bank Muamalat Bone Regency". The results of this study show that the mechanism for opening and closing accounts in early childhood savings is on the condition that the identity of the child who wants to open a savings account must already have a birth certificate and have been recorded in the family card, and the contract system used in this savings is to use a wadiah contract in the form of a entrustment
STRATEGI PENGEMBANGAN PRODUK PEMBIAYAAN SYARIAH KSPPS TERHADAP PENINGKATAN DAYA SAING DI KOPERASI BAKTI HURIA CABANG BONE
Authors: Pematasari Widya , Hidayati Darwis Rahma
Published: January 2023

This study discusses the strategy of developing sharia financing products for savings and loans cooperatives on sharia financing towards increasing competitiveness (KSPPS). KSPPS in performing its function is to collect, manage and distribute and distribute funds. The method used in this study is qualitative research as for the influence in the background with interview and documentation methods. The results of this study show that, the Sharia financing product system with a mudhārabah contract at the KSPPS Bakti Huria Bone Branch Cooperative, the existing financing is financing used to help the community which is carried out in the form of deposits and loans by making contracts in accordance with sharia principles. The level of competitiveness in the KSPPS Bakti Huria Bone Branch Cooperative must be gradual, meaning that the increase in competitiveness begins with efforts to win the competition. To find out the various conditions of competitiveness of cooperatives, a form of continuous development is needed, in order to improve the standard of living for cooperatives in the community. the strategy of increasing competitiveness in the KSPPS Bakti Huria Bone Branch Cooperative is through approaches, services and strategies for members of the KSPPS Bakti Huria Bone Branch Cooperative by conducting its payment system via online, namely through an application (member) and it does not stop there also the KSPPS Bakti Huria Bone Branch Cooperative teaches its members how to manage the money lent to members and assist in the business process.
An Overview of Univeristy Students’ Behavior in Using Tiktok On Their Daily Life
Authors: Syam Ferawaty , Meldawati Sri Fatta
Published: January 2023

The main objective of this research is to explore the students’ behavior in using TikTok on their daily life. This research employed descriptive survey with quantitative approach, the data were gained through online questionnaire which distributed to 26 students randomly. The data were analyzed using SPSS descriptive statistic to report the result of the survey. Based on the findings, it is reported that (1) the students is enjoying using TikTok, (2) most of the students at least using or opening the TikTok once a day (3) Entertainment video content become the most favorite content watched by the students,(4) the purpose for using TikTok is to entertain themselves, (5) there are no direct effect of using TikTok for their communication skill.
PENGARUH KONTRIBUSI PEMBIAYAAN MURABAHAH DAN MUDHARABAH PERBANKAN SYARIAH TERHADAP PENGEMBANGAN MICRO BUSINESS PERFORMANCE DI KOTA MEDAN
Authors: Nasution Nurselina , Anggraini Tuti
Published: January 2023

Penelitian ini bertujuan untuk menganalisis pengaruh pembiayaan murabahah dan mudharabah di terhadap pengembangan micro business performance di Kota Medan. Penelitian ini menggunakan metode kuantitatif. Analisis data menggunakan analisis regresi linier sederhana untuk mengetahui pengaruh antara variabel bebas dan variabel terikat. Populasi penelitian ini adalah 30 nasabah pembiayaan murabahah dan 19 nasabah pembiayaan mudharabah. Dengan demikian, seluruh populasi nasabah pembiayaan murabahah dan mudharabah digunakan sebagai sampel penelitian. Teknik pengumpulan data menggunakan angket dan dokumentasi untuk memperoleh data jumlah nasabah dan tentang perkembangan micro business performance. Hasil penelitian menunjukkan bahwa pembiayaan murabahah dan mudharabah berpengaruh positif signifikan terhadap perkembangan micro business performance di Kota Medan.

Kata Kunci: Pembiayaan Murabahah, Mudharabah, Micro Busines
Geçmişte ve Günümüzde Lycium barbarum L.’un Kullanım Alanları
Authors: DELİMUSTAFAOĞLU Fatma Gül , BALDEMİR KILIÇ Ayşe
Published: January 2023

Solanaceae familyasına ait özellikle Lycium barbarum L. türünün meyvesi olarak bilinen “Goji berry”, besin değerinin yüksek olması sebebiyle son yıllarda ‘‘süper meyve’’ adıyla oldukça popüler hale gelmiştir. L. barbarum çalı formunda çok yıllık bir bitkidir. Meyveleri tatlı ve keskin bir tada sahip, yaklaşık 2 cm derinliğinde elips şeklinde turuncu-kırmızı renkli yumuşak bir yapıya sahiptir. 2000 yılı aşkın süredir Çin ve Tibet’te geleneksel tıp ve gıda alanında kullanılan bitkinin kök, kabuk ve meyvelerinden tıbbi ilaçlar yapıldığı, yapraklarının ve tohumlarının da bazı şifalı bitkilerden bahseden kitaplarda yer aldığı anlatılmaktadır. Tibet’te yerliler tarafından ömrü uzattığı düşünülmekte ve ‘‘mutluluğun meyvesi’’ adıyla da bilinmektedir. Bitkinin dünyada “kurt üzümü” adıyla da bilinen meyveleri polisakkarit kompleksleri, karotenoidler, fenilpropanoidler gibi yüksek biyolojik aktiviteye sahip birçok bileşik grubu içermektedir. Bitkinin kurutulmuş meyveleri direkt tüketildiği gibi bitki çayı, meyve suyu, şarap, tentür yapımında ve yemeklerde olmak üzere dünyada farklı kullanımları bulunmaktadır. Bu çalışmada ise L. barbarum bitkisinin geleneksel kullanım alanları ile ilgili bilgiler derlenmiştir.
Kurkumin ve Naringenin’in Bakır Nanopartikülleri ile Oluşturulmuş Karaciğer Hasarı Üzerine Etkilerinin İncelenmesi
Authors: LALOU Hiba , YILDIRIM Metin , AKKAPULU Merih , YALIN Serap , YALIN Ali
Published: January 2023

Giriş: Bakır nanopartiküllerinin (CuNP) günümüzde kullanım sıklığındaki artış insanların bu maddeye olan maruziyetin artması ile sonuçlanmaktadır. Curcuma longa L. ve Naringenin kanser türlerinin oluşma riskinin azaltmakta ve insanlarda koruyucu biyolojik etkilere yardımcı olmaktadır. Amaç: Çalışmamızda, bakır nanopartiküller ile oluşturulmuş oksidatif strese karşı kurkumin ve naringeninin olası koruyucu etkileri incelenmiştir. Yöntem: Çalışmamızda 42 rat 6 gruba ayrılmıştır. Gruplardan biri kontrol grubu iken, diğer gruplara farklı dozlarda kurkumin ve naringenin maddeleri ile CuNP uygulanmıştır. Çalışma sonunda karaciğer dokusu izole edildi ve Süperoksit Dismutaz (SOD), Katalaz (KAT) aktiviteleri, Glutatyon (GSH), Malondialdehit (MDA) düzeyleri ve inflamasyon belirteçleri (IL-1α, IL-1β) araştırılmıştır. Bulgular: Elde edilen bulgular sonucunda, bakır nanopartiküllerin oksidatif stresi arttırdığı ve antioksidan enzim seviyelerinde düşüşe sebep olduğu; kurkumin ve naringeninin ise oksidatif stresi azalttığı ve antioksidan enzim seviyelerini arttırdığı saptanmıştır. Karaciğer dokusunda IL-1α parametresi incelendiğinde, kontrol grubu ve farklı dozlarda kurkumin ve naringenin CuNP ile karşılaştırıldığında, IL-1α düzeyinde azalma saptanmıştır. Bu düşüş istatistiksel olarak anlamlı değildi. IL-1β parametresi, kontrol grubuna kıyasla CuNP grubunda istatistiksel olarak anlamlı bir artış gösterdi (p<0.05). IL-1β düzeyi incelendiğinde diğer gruplara kıyasla CuNP grubunda artma saptanmıştır. Sonuç: İnsanların bakır nanopartiküllere maruz kalması durumunda oluşabilecek zararlı etkilerden korunma ve tedavi için kurkumin ve naringenin kullanılabileceği düşünülebilir.
Sanayi Toplumlarında Sağlığın Toplumsal Bir Kurum Olarak Ortaya Çıkışı
Authors: DERELİ Sercan , ŞAHİNOĞLU Serap
Published: January 2023

Toplum, toplumsal yapı ve kurumlardan oluşan bir bütündür. Toplumsal yapı, insanlar arasındaki düzenli ilişkileri ifade ederken toplumsal kurumlar bir toplumun gözettiği ihtiyaç ve hedeflerin yerine getirilmesinde görev alan toplumsal ilişkilerdir. Toplumlarda aile, din, ekonomi, siyaset ve eğitim olmak üzere beş evrensel kurum yer almıştır. Toplumsal yapıda meydana gelen dönüşümler, her bir toplum aşamasında bu kurumların yeniden yapılanmasına neden olmuştur. Öte yandan ilgili dönüşümler yeni kurumların ortaya çıkışına da zemin hazırlamıştır. Bu yeni kurumlardan biri olan sağlık, her ne kadar tüm toplum aşamalarında kendine yer edinmiş bir alan olsa da teknolojik gelişmelerin tetiklediği Sanayi Devrimi sonrasında ortaya çıkan sanayi toplumlarında kurumsallaşarak toplumsal bir kurum olma özelliği kazanmıştır. Kurumsallaşma, sağlık hizmetinin toplumsal bir ihtiyaç olarak belirmesi ve sistemli bir şekilde üretilmesi anlamını taşımaktadır. Sağlık alanının kurumsallaşması sürecinde Rönesans düşüncesi, teknolojik gelişmeler, sosyal politika anlayışının doğuşu ve piyasalaşma olgusu etkili olmuştur. Bu çalışmada, sanayi toplumlarında sağlığın; toplumsal bir kurum olma özelliğini nasıl kazandığı ve işlevlerinde ne türden dönüşümler yaşandığı geniş bir bakış açısıyla ele alınmaya çalışılmıştır.
Human Papillomavirus Knowledge and Cervical Cancer Screening Practice among Uzbekistan Women
Authors: Bolormaa Erdenetuya , Yusupov Bekhruz , Akhmedova Mukhabbat , Yoo Youk Jin , Choe Seung-Ah
Published: January 2023

Background: Data on the knowledge of the general population of Uzbekistan regarding human papillomavirus (HPV) infection and cervical cancer screening practices are limited. This study aimed to assess the association between the knowledge and practice of cervical cancer screening among women in Uzbekistan. Methods: A baseline survey was conducted with 445 women aged 20–59 years who visited one of the three health centres of Tashkent, Uzbekistan, in December 2020. A questionnaire on the knowledge of HPV infection and cervical cancer screening practices was administered. The knowledge score, defined as the sum of the number of correct answers to the knowledge questions and the prevalence of cervical cancer screening practices, was analysed. The adjusted relative risk (RR) and low knowledge score (<median) of (1) never screened and (2) not screened within 2 years for each demographic characteristic were calculated. Results: The median knowledge score was 10. Women who had been screened for cervical cancer accounted for 63.1% of the patients. Among them, 64.8% reported that their last cervical cancer screening test was within 2 years. A history of sexually transmitted diseases was associated with a lower risk of never being screened (adjusted RR = 0.43, 95% confidence interval [CI] 0.24, 0.78) and no screening within 2 years (0.54, 95% CI 0.30, 0.99). No university graduation was associated with a higher risk of not screening within 2 years (1.57, 95% CI 1.00, 2.47). Association between knowledge of HPV status and screening practices was not observed. Conclusions: Adequate knowledge of HPV and cervical cancer prevention may be insufficient for cervical cancer screening practices. This study provides context for the development of effective cervical cancer prevention strategies.
The Effects of Different Exercise Programs on the Prevention of Perinatal Depression: A Systematic Review and Meta-Analysis
Authors: Mai Shu-yuan , Liu Ye , He Hao-chong , Yan Xiao-ying
Published: January 2023

Background: To evaluate the preventive effect of different exercise programs on perinatal depression and to provide practical suggestions to guide the maternal daily exercise plan. Methods: Nine electronic bibliographic databases were searched from inception until 18 January 2022. Meta-analysis of all data was performed using RevMan 5.4. Results: Sixteen RCTs consisting of 2233 maternal cases were included. Compared to women in the control group, women who received exercise effectively prevented maternal perinatal depression (Std. mean difference [SMD] = –1.31, 95% confidence interval [CI] –1.40 to –1.21). Prenatal exercise (SMD = –1.45), aerobic exercise (SMD = –1.78), personal exercise (SMD = –2.03), <30 minutes per single duration (SMD = –1.84), >3 times a week (SMD = –1.91) was the best preventive measure of maternal depression. Conclusions: Exercise can effectively improve the mental health status of perinatal pregnant women, and different exercise start time, exercise content, exercise frequency, exercise form, and single duration of exercise can improve depressive symptoms differently. It is recommended that pregnant women begin from the prenatal period of personal aerobic exercise 3 times a week, each exercise lasting less than 30 minutes, and adjust appropriately according to their own physical conditions.
Targeting Glutamine Metabolism in Prostate Cancer
Authors: Bhowmick Neil , Posadas Edwin , Ellis Leigh , Freedland Stephen J , Vizio Dolores Di , Freeman Michael R , Theodorescu Dan , Figlin Robert , Gong Jun
Published: January 2023

Glutamine is a conditionally essential amino acid important for cancer cell proliferation through intermediary metabolism leading to de novo synthesis of purine and pyrimidine nucleotides, hexosamine biosytnehsis, fatty acid synthesis through reductive carboxylation, maintenance of redox homeostasis, glutathione synthesis, production of non-essential amino acids, and mitochondrial oxidative phosphorylation. Prostate cancer has increasingly been characterized as a tumor type that is heavily dependent on glutamine for growth and survival. In this review, we highlight the preclinical evidence that supports a relationship between glutamine signaling and prostate cancer progression. We focus on the regulation of glutamine metabolism in prostate cancer through key pathways involving the androgen receptor pathway, MYC, and the PTEN/PI3K/mTOR pathway. We end with a discussion on considerations for translation of targeting glutamine metabolism as a therapeutic strategy to manage prostate cancer. Here, it is important to understand that the tumor microenvironment also plays a role in facilitating glutamine signaling and resultant prostate cancer growth. The druggability of prostate cancer glutamine metabolism is more readily achievable with our greater understanding of tumor metabolism and the advent of selective glutaminase inhibitors that have proven safe and tolerable in early-phase clinical trials.
Prognostic Value of Estimated Glucose Disposal Rate in Patients with Non-ST-Segment Elevation Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention
Authors: Liu Chi , Zhao Qi , Ma Xiaoteng , Cheng Yujing , Sun Yan , Zhang Dai , Zhou Yujie , Liu Xiaoli
Published: January 2023

Background: Estimated glucose disposal rate (eGDR) is highly associated with all-cause mortality in type 2 diabetes mellitus (T2DM) cases undergoing coronary artery bypass grafting (CABG). Nevertheless, eGDR’s prognostic value in non-ST-segment elevation acute coronary syndrome (NSTE-ACS) following percutaneous coronary intervention (PCI) remains unknown. Methods: The population of this retrospective cohort study comprised NSTE-ACS patients administered PCI in Beijing Anzhen Hospital between January and December 2015. The primary endpoint was major adverse cardiac and cerebral events (MACCEs). eGDR was calculated based on waist circumference (WC) (eGDRWC) or body mass index (BMI) (eGDRBMI). Results: Totally 2308 participants were included, and the mean follow-up time was 41.06 months. The incidence of MACCEs was markedly increased with decreasing eGDR. Multivariable analysis showed hazard ratios (HRs) for eGDRWC and eGDRBMI of 1.152 (95% confidence interval [CI] 1.088–1.219; p < 0.001) and 0.998 (95% CI 0.936–1.064; p = 0.957), respectively. Addition of eGDRWC to a model that included currently recognized cardiovascular risk factors markedly enhanced its predictive power compared with the baseline model (Harrell’s C-index, eGDRWC versus Baseline model, 0.778 versus 0.768, p = 0.003; continuous net reclassification improvement (continuous-NRI) of 0.125, p < 0.001; integrated discrimination improvement (IDI) of 0.016, p < 0.001). Conclusions: Low eGDR independently predicts low survival of NSTE-ACS cases who underwent PCI.
Interpreting Infrared Thermography with Deep Learning to Assess the Mortality Risk of Critically Ill Patients at Risk of Hypoperfusion
Authors: Luo Jing-chao , Wang Huan , Tong Shang-qing , Zhang Jia-dong , Luo Ming-hao , Zhao Qin-yu , Zhang Yi-jie , Zhang Ji-yang , Gao Fei , Tu Guo-wei , Luo Zhe
Published: January 2023

Background: Hypoperfusion, a common manifestation of many critical illnesses, could lead to abnormalities in body surface thermal distribution. However, the interpretation of thermal images is difficult. Our aim was to assess the mortality risk of critically ill patients at risk of hypoperfusion in a prospective cohort by infrared thermography combined with deep learning methods. Methods: This post-hoc study was based on a cohort at high-risk of hypoperfusion. Patients’ legs were selected as the region of interest. Thermal images and conventional hypoperfusion parameters were collected. Six deep learning models were attempted to derive the risk of mortality (range: 0 to 100%) for each patient. The area under the receiver operating characteristic curve (AUROC) was used to evaluate predictive accuracy. Results: Fifty-five hospital deaths occurred in a cohort consisting of 373 patients. The conventional hypoperfusion (capillary refill time and diastolic blood pressure) and thermal (low temperature area rate and standard deviation) parameters demonstrated similar predictive accuracies for hospital mortality (AUROC 0.73 and 0.77). The deep learning methods, especially the ResNet (18), could further improve the accuracy. The AUROC of ResNet (18) was 0.94 with a sensitivity of 84% and a specificity of 91% when using a cutoff of 36%. ResNet (18) presented a significantly increasing trend in the risk of mortality in patients with normotension (13 [7 to 26]), hypotension (18 [8 to 32]) and shock (28 [14 to 62]). Conclusions: Interpreting infrared thermography with deep learning enables accurate and non-invasive assessment of the severity of patients at risk of hypoperfusion.
The Predictive Value of Inter Arm Blood Pressure Difference, Inter Leg Blood Pressure Difference and Ankle Brachial Index for Acute Aortic Dissection
Authors: Zhou Quan , Huang Sufang
Published: January 2023

Introduction: Abnormal inter arm systolic blood pressure, inter leg systolic blood pressure and ankle brachial index (ABI) are related to vascular diseases. Our aim was to evaluate the correlation of inter arm systolic blood pressure difference (IASBPD), inter leg systolic blood pressure difference (ILSBPD), and ABI with acute aortic dissection (AAD) and their role in predicting AAD. Methods: In this prospective case-control study, 180 patients with AAD admitted to the emergency department were prospectively and consecutively collected in Tongji Hospital from October 2019 to December 2020. 180 healthy people matched by sex, age and BMI served as control group. All participants were adults over 18 years of age who underwent four-limb blood pressure measurements. IASBPD, ILSBPD and ABI were compared between the two groups and their associations with AAD were analyzed. Results: A total of 360 patients (180 cases and 180 controls) were analyzed. In case group IASBPD was larger [(15.23 ± 16.15) mm Hg vs. (4.19 ± 3.63) mm Hg] and ILSBPD was larger (13.00 mm Hg vs. 5.70 mm Hg). ABI was smaller [(0.98 ± 0.24) vs. (1.12 ± 0.09)], and the difference was statistically significant (all p < 0.05). According to the receiver operating characteristic curve (ROC), IASBPD ≥10 mm Hg (Sen 61.7%, Spe 88.9%), ILSBPD ≥13 mm Hg (Sen 50.6%, Spe 80.6%) and ABI ≤0.9 (Sen 53.3%, Spe 87.2%), showed significant correlation with AAD (all p < 0.001). Conclusions: Compared with healthy people, IASBPD and ILSBPD levels were higher and ABI levels were lower in patients with AAD. IASBPD ≥10 mm Hg and ILSBPD ≥13 mm Hg can be used as indicators for early screening of AAD, and IASBPD ≥10 mm Hg has better predictive value for the occurrence of AAD. In patients with typical chest pain, attention needs to be paid to measuring blood pressure in the extremities.
Ambulatory Smartwatch ECG Monitoring among Patients Undergoing Transcatheter Aortic Valve Replacement Early after Discharge: An Observational Study
Authors: Zhang Yi , Xiong Tian-Yuan , Yang Xue-Mei , Chen De-Fang , Li Yi-Ming , Bao Yun , Chen Mao
Published: January 2023

Background: As an emerging arrhythmia monitor, ambulatory smartwatch electrocardiogram (ECG) provides an option for home-based monitoring of delayed new-onset arrhythmic events after transcatheter aortic valve replacement (TAVR). We aimed to validate the diagnostic efficacy of a consumer smartwatch ECG in TAVR recipients, while further explore the occurrence rate of both tachy- and brady-arrhythmia for 30 days after discharge to support risk management. Methods: Consecutive TAVR recipients from February 26th, 2021 to December 13th, 2021 were enrolled prospectively, receiving simultaneous 24-hour Holter and 12-lead ECG compared with smartwatch ECG during hospitalization and daily smartwatch ECG collection for 30 days after discharge. Results: Among 110 patients, the efficacy of smartwatch ECG presented sensitivity and specificity in diagnosing atrial fibrillation (AF) as 1.00 and 0.97, left bundle branch block (LBBB) as 0.61 and 0.88, and right bundle branch block (RBBB) as 0.60 and 0.97, respectively, compared with 24-hour Holter; presented sensitivity and specificity in diagnosing AF as 0.88 and 1.00, LBBB as 0.90 and 0.96, and RBBB as 0.83 and 0.94, respectively, compared with 12-lead ECG. At 30-day follow-up, new-onset arrhythmia included new-onset severe conduction disturbance (SCD) (23.6%), new-onset AF (21.8%), new-onset permanent LBBB (14.5%) and new-onset permanent RBBB (0.9%); 69.2% (36/52) of early new-onset LBBB recovered at 30-day follow-up. Conclusions: The diagnostic efficacy of consumer smartwatch ECG in arrhythmic events among TAVR population was acceptable, which provided a recommendable option for home-based management. Clinical Trial Registration: “Continuously ambulatory rhythm monitoring and predictors of electrocardio-related adverse events in 30 days after transcatheter aortic valve replacement”; Identifier: ChiCTR2000041244; http://www.chictr.org.cn/showproj.aspx?proj=66324.
Prevention of Sudden Death in Sports: A Global and Multidisciplinary Observatory for Scientific Research and Knowledge Transfer (PREMUBID)
Authors: Garatachea Nuria , Pueyo Esther , Eijsvogels Thijs M.H.
Published: January 2023

Background: The health benefits of sports and exercise training are well known. However, an acute bout of exercise transiently increases the risk of sudden cardiac death (SCD). To minimize the cardiovascular risks of exercise, more insight into the prevention and causes of SCD is needed. Methods: The observatory for the prevention of sudden death in sports, PREMUBID, was created with the aim of fostering research to assess the benefits and risks of exercise at different volumes and intensities and to get insight into the underlying mechanisms of potentially cardiac (mal) adaptations. Results: The observatory gathers researchers from a wide range of disciplines working at institutions in Europe and North America. The guiding principles of PREMUBID are to broaden the understanding of SCD in sports, strengthening collaborative research across the globe, and to develop, implement and evaluate robust pre-participation screening and emergency care strategies to further reduce the number of fatal cardiac events in sport events. During the inaugural meeting of the observatory, members and affiliated researchers discussed possibilities to initiate collaborative research projects and to exchange staff and students to share information and practices to prevent SCD. The final goal is to translate the obtained knowledge to understandable messages for the general population and healthcare workers to ensure that the population at large benefits from it. Conclusions: The PREMUBID consortium aims to produce novel knowledge and insights in SCD prevention, in order to maximize the health benefits associated with acute and long-term exercise training.
Brain MRI Images Generating Method Based on Cyclegan
Authors: Van Nguyen Hinh , Trong Thanh Han
Published: January 2023

Generating tumor images on a brain MRI image at random locations can help medical researchers and medical students in predicting possible tumor possibilities. In this study, we propose to apply CycleGan to create MRI images with brain tumors from MRI images without brain tumors, thereby increasing the number of MRI images with brain tumors. With the initial data set of 660 images without brain tumors, the CycleGan model has created a new data set of 660 images with brain tumors, aiming to increase the number of brain MRI images for future studies. The received results will be evaluated and compared to others studied based on FID score.
Study of Electromagnetic Shielding for Reduction of Magnetic Fields Generate by Underground Power Cables via a Finite Element Techinique
Authors: Bui Duc Hung , Cong Trinh Truong , Duong Minh Quan , Dang Quoc Vuong
Published: January 2023

Nowadays, with the development of the industries, the electrical types of equipment are used and applied widely for many different purposes. One of them is the use of power cables to transmit electricity over long distances, from generator stations to consumers. Local and global fields are usually created by the extensive presence of the types of currents following in power cables in general and underground cables in particular. Not only causes directly some unwanted effects on the body’s natural equilibrium, but electromagnetic fields can create the disturbance and cause interference with electronic devices. In this paper, a shielding plate is introduced to mitigate the local fields generated by a three phase current of underground power cables. The computation of magnetic fields is implemented with the magnetic vector potential formulations via a finite element technique. The developed method is applied to a practical problem.
Legal Protection of Doctors in Performing Medical Actions Based on Law Number 29 of 2004 Concerning Medical Practice
Authors: Murtini Sri , Thamrin  , Thalib Abdul , Chaidir Ellydar , Susilo Efendi Ibnu
Published: January 2023

This paper is a study that analyzes the legal protection of doctors in providing medical practice services based on law number 29 of 2004 concerning medical practice. Medical services provided to patients are called medical actions that aim to achieve a cure from an illness. Medical action certainly has risks for the patient in its implementation so that an agreement is needed from both parties, namely the doctor and the patient to carry out medical action, which is preceded by informed consent through a therapeutic transaction. The approach used in this study is a normative legal approach. The results of the study show that legal protection for doctors in carrying out medical actions is only stated in article 50 letter a, but it does not explain how the rules and procedures for legal protection for doctors themselves, more then regulate the patient's rights if they suffer a loss against a doctor's medical actions, This creates a feeling of injustice for the medical profession where lawsuits and demands from patients or the patient's family always use all legal domains, both criminal, civil and administrative which ignore the existence of an agreement in the approval of medical action and also violate the legal principle of ne bis en idem.
Kumpulan soal logika matematika
Authors: petrus salma
Published: January 2023

Kumpulan soal terkait materi logika matematika beserta kunci jawaban
A brief Survey on Different Topological Scenarios to Secure IoT devices
Authors: Hussain Shafiq
Published: January 2023

A brief Survey on Different Topological Scenarios to Secure IoT devices
Potassium in Red Blood Cells - A New Biomarker of Oxidative Stress by Sepsis
Authors: Ola Aranuwa Felix
Published: January 2023

Indocyanine Green Fluorescence–Guided Avoidance of BileDuct Injury During Simultaneous LaparoscopicFenestration and Cholecystectomy
News Trading in Indonesia’s Media: A Business in Shaping Public Opinion
Authors: Hasan  , Ubaidillah  , Muliawati  , Helmi  , Nofriadi
Published: January 2023

This study aimed to study the massive and systematic extent of money politics in the 2017 elections of the Bireuen District. This study used a qualitative method with the participant-observer approach. Data were collected through FGD at Al-Muslim University in Bireuen and in-depth interviews with the relevant parties. The practice of money-politics in the Bireuen election was very immaculate and well-coordinated. It started by collecting the photocopies of ID and family registry cards and ended with distributing the money before and after the voting. The campaign teams in each village helped to assist this process to the villagers. The study found five major causes of money politics in the Bireuen District. First, the public confidence in the political elections has declined. Second, the political orientation of the community was pragmatic. Third, several candidates had the same power in the election; thus, they had no other choices but to give away money to the public in the hope of being elected. Fourth, the prevention of money politics in the local elections of the Bireuen regent was somewhat weak. The elections supervisory committee does not have the authority to punish the political money perpetrators but could only give recommendations to the District Independent Elections Commission (KIP). These recommendations are subject to being processed or neglected. Lastly, the regulation of money politics was also weak in the Bireuen regional election. This massive money politics in Bireuen could be prevented by establishing a concept and formulating policies in the form of qanun (Islamic bylaws) in Aceh. The qanun could cancel or disqualify the regent candidates if they are proven to have committed money politics based on convincing and legally binding evidence. The political parties could also be deprived of their political rights to carry the regional head candidates for a term of office. Aceh, through its self-government, has a special authority to produce regulations that do not contradict the higher regulation in Indonesia. The function of the qanun is to break the chain and the money politics system by imposing punishment on the regent candidates and political parties. This research has never been investigated before, especially the regulation potential to break the chains of money politics by establishing a qanun to be applied in Aceh.
KONSEP EKONOMI PADA ZAMAN NABI
Authors: Nuraeni
Published: January 2023

Terdapat dua istilah yang sering digunakan untuk ekonomi Islam, yaitu ekonomi syariah dan ekonomi Islam. Keduanya merujuk satu azas, yakni ekonomi yang berdasarkan prinsip syariah. Dilihat dari segi berkembangnya, ekonomi syariah lahir dan berkembangnya agama Islam di dunia ini. Pada fase ketika Rasulullah masih di Makkah, kegiatan ekonomi belum sempat dilakukan sebab perjuangan dan fokus dakwahnya dalam rangka menguatkan ketauhidan pada orang-orang Quraisy yang menyembah berhala. Kegiatan ekonomi Rasulullah baru terlaksana ketika beliau berada Madinah dengan menata pemerintahan sekaligus menata perekonomian masyarakat Madinah.
Governance Issues and Environmental Impacts of Oil Palm Plantations in Riau (A Green Criminology Overview)
Authors: Marito Christian , Simon Arthur Josias , Sulhin Iqrak
Published: January 2023

Indonesia, as an agrarian country, has a wealth of natural resources that can be used to meet human needs, either directly or indirectly through economic activities. One of the initiatives done is through the growth of oil palm farms, which is increasing in pace with global demand. Riau Province owns the majority of Indonesia's oil palm plantation land. Palm oil is a significant commodity in Riau, and with first-rate production, Riau Province can be considered a national center for oil palm development. This article will discuss two major aspects of oil palm plantations in Riau. First, it is concerned with the multiple detrimental effects of oil palm plantations in Riau, both environmental and socioeconomic. Second, this study will discuss several concerns concerning the governance of oil palm plantations in Riau. This study employs qualitative research methodologies, with a literature review serving as the primary data collection method. In this study, the literature review refers to gathering information from multiple books, journal articles, regulations, and other supporting papers. A literature review is conducted to examine prior studies on environmental criminality, green criminology, oil palm plantations, and oil palm plantation management in Riau. Finally, three conclusions are proposed in this study. The first conclusion is about the conflicting laws and regulations. In Indonesia, laws in the form of exemptions or permits must seek rechtsbeginsel, which must be rational or logical. Based on the nature of the prior first difficulty, the second conclusion speaks to the nature of bureaucracy. Bureaucracy with a criminogenic nature allows for the growth of forms of power abuse and maladministration. Since this deviation can cause harm, it is classified as a crime. In this situation, there is both social and environmental harm. The third conclusion in this discussion is the vulnerability to abuse of power as a result of power distribution. As a result, especially in the context of the oil palm plantation crisis, the end of the fraud committed by private investors that should be rectified by the political elite will not be fixed: it will reoccur as a true result of terrible governance practices carried out compactly.
A single nucleotide variant on chromosome 2 residing within LINC01830 distinguishes patients with normal-like breast cancer.
Authors: Mamoor Shahan
Published: January 2023

Molecular subtypes including the normal-like subtype drive patient outcomes in human breast cancer but the biological basis underlying subtype-specific disease is not completely understood (1-4). We mined published microarray data (5) to discover in an unbiased fashion the most distinguishing genetic features of tumors of each breast cancer molecular subtype. We identified a single nucleotide polymorphism on chromosome 2, rs6544021, as among the most significant genetic differences in the tumors of patients with normal-like breast cancer. Sequence variation in the LINC01830 gene may be important in understanding differences in genetic background that favor development of normal-like subtype human breast cancer.
Estudo das Propriedades Psicométricas da Versão Brasileira da Escala de Intenção de Ativismo e Radicalismo
Authors: Berrondo Barbara Aires Borges , Modesto João Gabriel Nunes , Couto Cleno , Filho Mario Gloria , Rueda Fabian J M
Published: January 2023

A política brasileira tem sido caracterizada por uma polarização ideológica e consequente radicalização dos indivíduos, tornando-se relevante a validação de instrumentos que possibilitem análises confiáveis sobre o comportamento político no país. Nesse sentido, este estudo apresenta as propriedades psicométricas da Escala de Intenção ao Ativismo e Radicalismo para o contexto brasileiro. A pesquisa contou com 389 participantes. A Análise Fatorial Exploratória indicou uma representação bifatorial do fenômeno, corroborando a estrutura da versão original, com cargas fatoriais elevadas e sem evidência de itens com cargas cruzadas. A fidedignidade composta dos fatores, a medida de replicabilidade da estrutura fatorial e os índices de ajuste foram adequados. Com base nisso, conclui-se pela adequação do instrumento para o contexto brasileiro, ressalta a confiabilidade dos resultados de estudos anteriores, e permitirá o avanço na compreensão do radicalismo político no país.
Influence of Emotional Outcome Valence on Sense of Agency in a Free Choice Task
Authors: Ari Ilkay , Yildirim Funda
Published: January 2023

Sense of agency (SoA) is a subjective feeling of being the author of one's voluntary actions and their outcomes. Several studies demonstrate that SoA is modulated when the outcomes are affective. However, the research on the influence of emotional outcomes on SoA have yielded somewhat contradictory results. Some studies suggest that the SoA is increased when the outcomes are positive while others conversely suggest that it is diminished compared to negative outcomes, specifically in a moral or social context. This study examined the influence of outcome valence on SoA with a temporal binding paradigm, by manipulating emotional valence and outcome delays. Participants chose between two actions with key presses which randomly produced one of positive (happy), negative (sad) or neutral emoticons after varying delays and judged the interval between their key press and the outcome. The results revealed a significant interaction between outcome valence and delay, which suggested that specifically at 500 ms of delay, perceived intervals were reliably shorter (i.e., stronger binding) between key presses and negative outcomes compared to positive outcomes. Our findings suggest that a negative valence might improve an individual's capacity for SoA when they are presented with an action choice and are unable to predict the outcomes in a social-emotional environment.