bluuebunny/crossref_metadata_2025 huggingface dataset:
Physiochemical Properties, Anti-pathogenic and Anti-tumour Activity of Whey based Probiotic Muskmelon Health Beverage
Authors: Krishnaprabha V. , Ramakrishnan Lalitha , Vijayaraghavan R. , Unnikrishnan Gayathri
Published: January 2023

Background: Muskmelon (Cucumis melo) was a beautiful, juicy, tasty fruit of the Cucurbitaceae family which includes 825 species in 118-119 genera. It is also rich in antioxidant flavonoids such as carotene, Vitamin C, lutein, adenosine, zea-xanthin and cryptoxanthin and the folic acid present in the fruit is very good for pregnant women and makes the baby healthy and it helps to prevent the neural tube defects. Whey and whey based products had relatively high lactose content which forms a suitable substrate for probiotics in the intestine and it increased the absorption of calcium. Methods: A probiotic beverage was prepared by using whey water and muskmelon incorporation. Result: Product developed with whey protein at 60% incorporation received highest acceptability score. No statistically significant difference was found between the control and Whey protein incorporated muskmelon beverage. The nutrient content of V2 was higher than other variations. Conclusively, the incorporation of whey water, muskmelon (rich in antioxidants) and probiotic could prevent our body from various disease conditions and it has potential health benefits disease.
Dimensões da informatização dos tribunais
Authors: Silva Paulo Eduardo Alves , Yeung Luk Tai Luciana
Published: January 2023

A informatização dos tribunais brasileiros produz impactos variados, desde a organização e funcionamento de cartórios e varas judiciais até mudanças no próprio perfil da advocacia de contencioso judicial. Este artigo destaca alguns desses efeitos, identificando suas origens e prováveis encaminhamentos, a partir do levantamento de percepções dos advogados(as). De modo geral, os resultados corroboram a percepção de vantagens decorrentes da informatização. Todavia, entraves técnicos intensificam os trâmites burocráticos, além de esvaziarem os balcões dos cartórios, afetando a dinâmica relacional que era ali praticada. A imagem de um tribunal mais distante e um cliente próximo torna-se mais explícita aos advogados. Se para alguns, a informatização pode resultar na concepção de novos produtos e serviços, para outros pode significar a precarização quando não simplesmente o abandono antecipado da profissão. O artigo conclui que a informatização produz transformações estruturais nas atividades jurídicas que vão nuito além do funcionamento e gestão dos tribunais e que a compreensão das dimensões dessa mudança, sobretudo no campo das profissões jurídicas, merece ocupar espaço prioritário em agendas de pesquisa e políticas públicas de informatização.
INDONESIAN ISLAMIC CENTRE LONDON
Authors: Reny Wulandari  , Sujadi
Published: January 2023

The efforts of Indonesian Muslims to exist among other Muslim ethnics in London from 1960s up today have not given impacts yet. Their existence has not played an important role in spreading Indonesian Islam and not lead to establish a big mosque there. Therefore, this article discusses about how was their history prior to its Indonesian Islamic Centre (IIC)?; and how far did the IIC make efforts to develop Indonesian Muslims in London? Therefore, this article aims to explore its contributions for Indonesian Muslims there, leading to contribute to the Embassy of Republic of Indonesia in the Great Britain and local ruling government there in social-cultural field. Dealing with this, historical method: heuristic, verification, interpretation, and historiography and social history approach on the great efforts of ordinary people are used. In conclusion, the efforts for an Indonesian mosque need more time in spite of having a house serving as a charity foundation and holding bold solidarity and unity for them regularly. This is inseparable from its mission as a uniting spot. Subsequently, ICC’s board members have been able to provide legal marriage service under Indonesian and British laws. All the results show that they should make more significant efforts.

 

ABSTRAK

Keberadaan Indonesian Islamic Centre (IIC) bagi komunitas muslim Indonesia di London hingga kini belum berdampak besar dalam mensyiarkan model Islam Indonesia di tengah-tengah etnis muslim lainnya. Oleh karena itu, penelitian ini mendiskusikan tentang bagaimana sejarah muslim Indonesia sebelum adanya IIC?; dan sejauhmana kiprah IIC untuk mengembangkan eksistensi muslim Indonesia di London? Penelitian ini bertujuan mengeksplorasi kontribusi organisasi tersebut dalam memenuhi kebutuhan keagamaan dan sosial umat Islam Indonesia sehingga diharapkan dapat memberikan sumbangsih pemikiran terutama kepada Kedutaan Besar Republik Indonesia (KBRI) di Inggris dan pemerintah lokal. Dalam mengkaji subyek-subyek tersebut digunakan metode sejarah yaitu metode yang menggunakan tahapan-tahapan: heuristik, verifikasi, interpretasi hingga historiografi dan pendekatan sejarah sosial – pendekatan yang memfokuskan pada usaha-usaha rakyat dalam perjuangannya. Setelah melakukan analisa historis, ada beberapa kesimpulan: pertama, perjuangan untuk menghadirkan masjid yang memadai untuk umat Islam Indonesia di London masih memerlukan waktu panjang walau organisasi itu sudah membeli sebuah rumah yang dijadikan yayasan amal. Kedua, IIC sudah bersaha mewadahi berbagai kegiatan keagamaan dan sosial-budaya anggotanya komunitas muslim Indonesia di Inggris secara regular. Ketiga, penyelenggaraan pernikahan juga menjadi perhatian serius IIC dengan mempertimbangkan hukum-hukum pernikahan yang berlaku di Indonesia dan di Inggris. Semua hasil ini menunjukkan bahwa mereka masih perlu melakukan hal-hal yang lebih berdampak.
Pengaruh Penerapan Metode Core (Connecting, Oranizing, Refleting dan Extending) Materi Nilai-Nilai Moral Pancasila terhadap Hasil Belajar Siswa di Madrasah Ibtidaiyah
Authors: Shawmi Ayu Nur , Jadiddah Ines Tasya , Saputra Agra Dwi
Published: January 2023

Pendidikan kewarganegaraan (PKn) menjadi bagian penting dalam suatu pembelajaran di sekolah baik formal maupun informal. Hal itu dapat dilihat dari keberadaan pendidikan kewarganegaraan yang berstatus wajib dalam kurikulum pendidikan. Keberadaan pendidikan kewarganegaraan terealisasi nyata disetiap jenjang pendidikan dimulai dari sekolah dasar (SD) Berdasarkan hasil Penelitian yang dilaksanakan dalam pembelajaran PPKn materi nilai-nilai moral Pancasila dengan menerapkan model CORE pada siswa kelas V Mi Sultan Mahmud Badaruddin Palembang dapat disimpulkan bahwa terjadi peningkatan Pemahaman materi tentang niali-nilai moral Pancasila setelah dilakukannya penerapan atau observasi menggunakan Metode CORE pada siswa kelas V Mi Sultan Mahmud Badaruddin , hal ini dapat di simpulkan Metode CORE memiliki pengaruh terhadap pemahaman peserta didik di Madrasah Ibtidaiyah
La práctica de valores humanos en estudiantes universitarios desde una perspectiva de género.
Authors: Santoyo Manzanilla David de Jesús , Ortiz Pech Rafael , Rivera de la Rosa Alba Rosa
Published: January 2023

El tema de los valores humanos es novedoso desde la perspectiva de género y educativa de modo que debe ser estudiado. Por tanto, este estudio tiene como objetivo averiguar cómo los valores humanos se ponen en práctica por universitarios (hombres y mujeres) bajo diversos escenarios reales como la casa, escuela, lugar de trabajo, profesores y padres. Para cumplir con el objetivo se toma una muestra intencional del estudiantado de una universidad pública y se analiza cualitativamente usando la herramienta conocida como “nube de palabras”. Los resultados muestran la existencia de coincidencia en la práctica valores humanos entre hombres y mujeres estudiantes bajo los diversos escenarios reales. Se concluye que la práctica de valores humanos entre hombres y mujeres continua y su permanencia será vigente sin importar lugar y tiempo. De igual modo, la práctica de valores aplica para todos y la universidad en su función formadora de capital humano deberá incluir estos temas en sus planes de estudio, aunque no hay un consenso general de lo que es universalmente aceptado como ético.
A pintura no século XIX
Authors: Coli Jorge
Published: January 2023

Em 1927, Henri Focillon (1881-1943), historiador da arte francês, publica em Paris o livro La peinture au XIXe siècle: le retour à l’antique, le Romantisme, seguido, no ano seguinte, por La peinture au XIXe et XXe siècles: Du Reálisme à nos jours. Os volumes, editado por H. Laurens, integravam a série Manuels d’Histoire de l’Art, sob direção de Henry Marcel, antigo diretor dos Museus Nacionais de França. A coleção tinha por objetivo “retraçar, em uma série de obras distintas, a história e a evolução de cada forma de arte”, das “origens” ao século XX. A tradução em português a seguir apresenta ao leitor a introdução do primeiro volume de Focillon, em que ele define as chaves para a compreensão da arte do século XIX.
Evaluating the performance of human resources management at Amran University in light of the requirements of sustainable development
Authors: أمين د. عبد الجبار الطيب , مغربه د. فهد صالح قاسم , كرشوم د. عبد الله يحيى هادي , الصالحي أ. بسمة عبد الجليل
Published: January 2023

The study aimed at Evaluating the performance of human resources management at Amran University in light of the requirements of sustainable development. The researchers used the descriptive analytical approach. The tool consisted of a questionnaire of (37) phrases, divided into four dimensions; It was distributed to a random sample of (40) academic and administrative leaders. The results of the study showed that the tool’s overall score was (3.02 out of 5); With a performance rating of (medium), and at the level of the main dimensions, the incentives and compensation dimension got the highest average (3.30), then training and development with an average of (3.12), then performance evaluation (2.90), and finally selection and appointment with an average of (2.77), all of them with an average rating (average), The results also showed that there were no statistically significant differences between the answers of the sample according to the variables (gender - educational qualification - college), and the existence of a medium relationship between human resource management and the requirements of sustainable development, based on the results; The researchers recommended developing the performance and governance of human resources, paying fair wages, salaries and incentives, developing human resources skills through training, and setting controls to measure the performance of employees according to accurate standards, in addition to proposals for complementary studies on the subject.
The Effect of E-learning on the level of Educational Attainment Among Secondary School Students in Balqa Governorate – Jordan
Authors: ابورمان امينة عبدالرزاق
Published: January 2023

The study aimed to reveal the impact of e-learning on the level of educational attainment of secondary school students in Balqa Governorate from their point. The researcher used the descriptive analytical approach. He developed a scale consisting of (30) items distributed and applied it to a sample of (121) teachers who were randomly selected from various public and private schools in Balqa Governorate High, And there are differences in the impact of the e-learning system on the level of educational achievement among secondary school students due to the variable of gender and in favour of females, and due to the variable of parents educational level and in favour of the graduate studies campaign, and in light of the results of the study, the researcher presented a set of recommendations.
Dimensão pedagógica da Gestão Escolar: planejamento, avaliação e prática do currículo
Authors: Duvernoy Doriele Silva de Andrade Costa , Barros Lyza Gennifer Moreira de
Published: January 2023

Este artigo apresenta uma análise da relação gestão escolar-currículo, a partir do olhar de gestores de escolas públicas de uma rede municipal de ensino da região metropolitana do Recife, PE. Situamos o planejamento, a avaliação e a prática do currículo como eixos da atuação da gestão escolar, numa perspectiva que considera a dimensão pedagógica como centro do trabalho do gestor ou da gestora. Trata-se de uma pesquisa qualitativa, na qual adotamos a abordagem metodológica da pesquisa-ação. Com isso, temos o propósito de investigar de que maneira a dimensão pedagógica pode ser potencializada por meio da implementação do currículo na escola. Constatamos elementos que apontam o campo semântico do conceito de currículo, contextos de atuação da política educacional em curso e as especificidades dos papéis de cada segmento envolvido nas práticas curriculares desenvolvidas na escola.
Currículo cultural na aula de História: um estudo de caso
Authors: Silveira Samara Souza , Ferrari Anderson
Published: January 2023

Partimos da compreensão de que os diferentes espaços sociais em que circulamos divulgam e instituem práticas discursivas, que podem ser lidas como currículo que fomenta modos de vida e que participam do jogo da produção de verdades. Isso significa dizer que seguimos as perspectivas teóricas pós-críticas que entendem que os currículos não se restringem às disciplinas escolares e aos saberes nelas constituídos, mas se fazem presentes em diversas culturas e artefatos culturais. É o conceito de currículo cultural que nos conduz a problematizações em torno de um artefato cultural que foi utilizado como suporte para uma aula de História sobre os silenciamentos na Revolução Russa realizada numa escola pública federal, em 2022. Trata-se de um vídeo com o discurso da vereadora Marielle Franco, no Dia Internacional da Mulher. Nosso propósito é assumir a problematização como metodologia, a qual nos convida a pensar os discursos que organizam a fala, assim como a utilização do vídeo como artefato cultural potente para pensar as relações entre currículo escolar e currículo cultural não escolar.
Microplastic Contamination in Marine Fish and Shells in the Coastal Areas of Jember Regency, Indonesia
Authors: Ningrum Prehatin Trirahayu , Negoro Abul Haris Suryo , Indahyani Didin Erma , Kusnadi  , Nurdiansyah Yanuar
Published: January 2023

Highlight Research

Fish and shellfish on the coast of Payangan and Puger
Several types of microplastics were detected in their gastrointestinal tract
There were microplastic types of fiber, fragments, granules, and filaments

Abstract
Every year, it is estimated that the Indonesian seas receive 100,000-400,000 tons of plastic waste used for human consumption. Indiscriminate disposal of plastic waste will have an impact in the future. The problem of microplastics is an illustration that the use of plastic in daily activities will cause environmental ecological damage. The purpose of the study was to describe microplastic contamination in marine fish and shells in the coastal areas of Jember Regency, Indonesia. The method used is to detect and identify the type and numbers of microplastic particles in the gastrointestinal tract content of sea fish and shells obtained from fishermen around Payangan and Puger coastal Jember, Indonesia. The gastrointestinal tract was extracted with peroxide oxidation method (WPO). A light microscope was used to examine microplastic particles of types and numbers. The results showed that marine fish and shells in the coastal area of Jember Regency, Indonesia have been contaminated with microplastic. The microplastic in each marine fish and shells sample has a different type. There were microplastic types of fiber, fragments, granules, and filaments in the shells sample, while in the marine fish samples, there were all these types except granules. Fish and shellfish on the coast of Payangan and Puger had several types of microplastics detected in their gastrointestinal tract.
Coronavirus (COVID-19) Impacts on Malaysian Fisheries Sectors: Lesson Learned from the Movement Control Order (MCO)
Authors: Mohd Arzaman Ameer Farhan , Salleh Hayatul Safrah , Embong Abdul Mutalib , Kadhim Kais Amir , Afzainizam Norzamziah , Pham Loi Hoang Huy Phuoc , Abdul-Kadir Nurul Ashikin , Mohd Nasir Nur Yuhanis
Published: January 2023

Highlight Research

The COVID-19 pandemic has caused an increase in the price of marine resources and the income of coastal communities has been affected.
The government and the authorities need to come out with several incentives to control this condition and the request for fish markets can be met customarily without rising prices and declining marine resources.
Malaysian Fisheries Development Authority (LKIM) a body that has a direct link to the fishing industry needs to ensure that all fishermen's associations participate in the purchase and marketing of fishermen's catch.
Adaptation of fish producers will pave the way for all coastal communities to develop more organized fishing systems and sufficient food sources

 
Abstract
COVID-19 has a significant impact on the fishery industry, economy, and food supply. The government of Malaysia imposes a Movement Control Order (MCO) to curb the spread of COVID-19 infection. Although the MCO implementation has benefits in terms of public health, it has affected the fishery industry and the livelihood of coastal communities in Malaysia. This study aimed to identify the impact of the COVID-19 pandemic on the fishery industry and their livelihoods during that period of calamity. Qualitative research and thematic analysis were employed to seek deeper information on the real situation that retards the fishing activities to the opt stage. COVID-19 has already revealed gaps in health care, the economy, and food systems. The findings obtained can provide recommendations to the government to provide initiatives to fishermen to help them maintain and improve their livelihood. However, this study has limitations as the number of respondents is relatively small due to the restrictions of movement allowed by the government. Future studies could be further enhanced in terms of the impact of COVID-19 after movement restrictions have been loosened and could use a quantitative approach to obtain significant data.
Doege-Potter Syndrome: A Rare Paraneoplastic Syndrome of Solid Fibrous Tumors Reported in Indonesia
Authors: Widjaja Jahja Teguh , Syarief Peter , Nathania Evelyn , Prameswari Ayunda , Hoo Yumilia
Published: January 2023

Introduction: Solitary fibrous tumors (SFT) is a rare group of tumor. Even rarer, it is associated with Doege-Potter syndrome (DPS), which manifests as hypoglycemia due to paraneoplastic syndrome. From searching through national reports and articles, this was the first case of DPS in Indonesia.
Case: A 60-year-old woman was admitted to the emergency department with dyspnea and unconscious. The patient’s glucose level showed 21mg/dL. A solid mass on the patient’s right lung was shown on the chest X-ray. A previous biopsy concluded that the patient had a solid fibrous tumor with a history of profound hypoglycemia. The patient underwent tumor resection and got a biopsy of the tumor. After resection, the patient showed no sign of hypoglycemia, and the blood glucose level was stable. We concluded that the patient had DPS, a paraneoplastic syndrome associated with the solid fibrous tumor.
Conclusion: Performing an adequate examination and giving prompt treatments can increase the patient’s quality of life, even though it is a rare disease and hard to diagnose. The patient’s condition, evaluated from a clinical condition, chest X-ray, and blood glucose, was better than before getting radical resection.
Preparation and Findings in Diagnostic and Therapeutic Flexible Fiberoptic Bronchoscopy Procedures in Patients with COVID-19
Authors: Pratomo Irandi Putra , Baskoro Hario , Soehardiman Dicky , Prasenohadi Prasenohadi , Kinasih Tutug , Fauzi Ahmad , Maretta Ike , Putri Nachita , Tokumo Kentaro
Published: January 2023

The coronavirus disease 2019 (COVID-19), which has raised concerns about infection control for every clinical procedure, including flexible fiberoptic bronchoscopy (FFB), has drawn the attention of clinicians across the globe. A pulmonologist frequently conducts this procedure to diagnose and treat pulmonary diseases like COVID-19. This procedure involves direct airway observation and generates aerosol from the patient. However, it is considered a double-edged sword, as the risk of infection and instrument contamination always haunts its clinical benefit to the patients and the operators. Therefore, a guideline for preparing and indicating FFB in COVID-19 must be addressed appropriately by emphasizing the importance of infection prevention and control. Fortunately, several recommendations and findings have emerged over the past three years, which should support safe FFB procedures for its operators with controlled infection. This study summarizes the indication, objective, contraindication, risk, preparation, and findings in diagnostic and therapeutic FFB patients with COVID-19.
Liver fibrosis in nonalcoholic fatty liver disease patients: noninvasive evaluation and correlation with cardiovascular disease and mortality
Authors: Ballestri Stefano , Mantovani Alessandro , Girolamo Maria Di , Baldelli Enrica , Capitelli Mariano , Lonardo Amedeo
Published: January 2023

Liver fibrosis is critical for liver-related outcomes and mortality in chronic liver disease, irrespective of etiology, including nonalcoholic fatty liver disease (NAFLD). NAFLD has been viewed as an independent correlate of cardiovascular risk. This review article briefly describes the cellular and molecular pathomechanisms underlying hepatic fibrosis. We then address noninvasive assessment of liver fibrosis. Finally, we discuss published evidence supporting fibrosis biomarkers’ role in assessing cardiovascular risk among patients with NAFLD. While histological assessment is the diagnostic standard of hepatic fibrosis, we specifically address noninvasive techniques, including equations based on anthropometric parameters, laboratory indices, and elastometry obtained with imaging techniques. The former group includes AST: ALT ratio, the Forns Index, the AST-to-platelet ratio index score, BARD (BMI, AAR, Diabetes) score, the fibrosis-4 index (FIB-4), the NAFLD fibrosis score, the gamma-glutamyl transferase-to-platelet ratio, and the Hepamet fibrosis score. The latter comprises elastographic techniques associated with ultrasonography or magnetic resonance. Our literature review identified numerous studies demonstrating that biomarkers of fibrosis (the most common being FIB-4) and elastographic techniques predict overall mortality and major cardiovascular events among NAFLD patients. The mechanisms accounting for this association are briefly reviewed. In addition to assessing hepatic fibrosis at baseline, during follow-up, and after therapeutic interventions in NAFLD patients, noninvasive assessment of hepatic fibrosis may predict cardiovascular events and overall mortality in these patients.
Comparative study of predisposition to thrombosis with administration of known systemic hemostatic agents and fibrin monomer in the experiment
Authors: Vdovin V. M. , Shakhmatov I. I. , Momot A. P.
Published: January 2023

Aim. To compare predisposition to thrombosis caused by administration of known systemic hemostatic agents and fibrin monomer under the conditions of normal coagulation versus drug-induced hypocoagulation in the experiment.

Materials and methods. The prothrombotic effect of intravenous (IV) administration of various systemic hemostatic agents was compared in a series of in vivo experiments. These agents included fibrin monomer (FM) (0.25 mg / kg), prothrombin complex concentrate (PCC) (40 IU / kg) or recombinant factor VIIa (rFVIIa) (270 mcg / kg). The studies were conducted under the conditions of hypocoagulation induced by the administration of warfarin (per os at a dose of 0.4–0.5 mg / kg / day for 14 days) or dabigatran etexilate (per os at a single dose of 15–20 mg / kg). Hemostatic system parameters were evaluated using thromboelastometry and calibrated automated thrombography.

Results. It was found that PCC reversed anticoagulant effects and led to an overcompensated increase in the density characteristics of the blood clot along with an excessive increase in thrombin generation in the groups of animals with warfarin-induced coagulopathy. The use of PCC and rFVIIa in the groups of animals with dabigatran-induced hypocoagulation also resulted in an increase in blood thrombogenic properties. In the administration of PCC, it was manifested though an increased D-dimer level and in administration of rFVIIa – through an increase in the clot density characteristics. At the same time, replacement of these hemostatic agents with FM did not affect the hemostatic system parameters.

Conclusion. FM at a dose of 0.25 mg / kg, as opposed to PCC and rFVIIa, is safer in terms of the risk of thrombosis.
HOW DO YOUNG PEOPLE TRAVEL? – EVIDENCE FROM CROATIA AND SERBIA
Authors: Vukadin Marija , Račićević Nikoleta , Marković Magdalena , Soldić Frleta Daniela
Published: January 2023

Purpose – Young people represent a significant segment of the tourism market, accounting for 23% of the total tourism market, according to UNWTO. This segment provides socio-economic opportunities for local communities as young travellers boost local tourism businesses, foster closer social interaction with host populations, and engage in environmental protection. The purpose of this research is to identify the basic characteristics of travel among young people from Croatia and Serbia and to determine which elements are most important to them when choosing a destination, while also determining whether there are differences between respondents from these two groups. Methodology - an online survey was conducted in Croatia and Serbia. The sample includes young people between the ages of 15 and 30. Descriptive statistical analysis was used to create the sample profile. Pearson’s chi-square tests and Mann-Whitney U tests were performed to detect significant differences between young respondents from Croatia and those from Serbia. Findings – The results of this study show that marketers can consider Croatian and Serbian youth travellers as a single market segment, because they are indistinguishable in many ways. Their motives and activities at the destination are similar, as are the elements by which they choose their holiday destination. Their attitudes toward sustainability issues also do not differ. Originality of the research – There is a considerable amount of academic research on young people and their travel. However, few studies have examined the travel of young people from Southeastern Europe or the attitudes of young people who experienced the pandemic. This study aims to fill this gap by providing insights into the attitudes of young travellers from Croatia and Serbia and what they look for when choosing a travel destination. Another important contribution is that this study also captures the views of young people from neighbouring countries, which provides an opportunity for comparison. This information will enable the destination management targeting young tourists to create tailored offers for the young population, which will have a positive longterm impact on the economy and the local community.
TRENDS IN HOSPITALITY HIGHER EDUCATION: ANALYSIS OF EDUCATION PROGRAMS IN FIRST 15 QS WORLD UNIVERSITIES
Authors: Ivančić Ivana , Mikinac Krešimir , Ćorluka Goran
Published: January 2023

Purpose - The changes caused by economic and technological development are present in all sectors of an advanced industrial society. The educational sector as such is not exempt from such changes; on the contrary, changes in the educational sector are becoming necessary. The challenges in transforming the entire educational system affect all segments of the educational process, including curricula, learning materials, teaching practices, and educational stakeholders. The hospitality industry, as a part of the overall economy based on human resources due to its specificity, is different from other industries and as such has a direct impact on the design of the educational model for future hospitality employees. Methodology - This paper aims to identify trends in higher education institutions for the hospitality industry, with a particular focus on analyzing the top 15 QS ranking world universities. The focus of the paper is to identify the challenges faced by higher education institutions specializing in the field of hospitality education and to analyze the educational programs that respond to the challenges and needs of the market. For the analysis of the collected data, the study used a qualitative methodology, employing a summative content analysis. Findings - The analysis of the educational system of established universities in the field of tourism and hospitality provides insight into specific teaching models for the hospitality industry. The results of the research showed that the focus of universities is in the segment of a tailor-made specialization, an internship in high-quality hospitality brands, and subjects that have foundations in hospitality, management, food and beverage, and marketing. Contribution - The research findings of this paper provide insight into the direction of further innovation of degree programs specializing in the hospitality field.
CONTENT ANALYSIS OF TRIPADVISOR ONLINE REVIEWS: THE CASE OF VALAMAR RIVIERA HOTELS IN DUBROVNIK
Authors: Višković Karmela , Rašan Dora , Prevolšek Denis
Published: January 2023

Purpose - From its foundation until today, Valamar Riviera hotels are one of the leaders in the Croatian hotel industry. Their strong positioning on the market is recognized throughout Europe, and this is particularly visible through the high ratings of former guests on social networks. Online reviews have become an excellent source for capturing the entire experience, which is why potential guests looking for accommodation are increasingly inclined to search platforms such as Tripadvisor for past experiences of previous guests. Based on the above, the purpose of this research was to gain insight into the factors that influence the overall experience of the guests of the Valamar Riviera Hotel. Methodology - For the purpose of this research, online reviews of three Dubrovnik’s Valamar Riviera hotels were analyzed. Online reviews were scraped from the Tripadvisor platform with the help of the ParseHub software for the period from January 1, 2020 to July 1, 2022, after which a sentimental analysis was performed on a sample of 261 online reviews. Based on the results of the sentimental analysis according to factors and connotation, a cause-and-effect diagram was created. Findings - Obtained empirical results indicate that positive comments from former hotel guests are leading for all three samples. Such results were expected; given that these are hotels that won the Tripadvisor Excellence Award. Former guests of Dubrovnik’s Valamar Riviera hotels who wrote online reviews on Tripadvisor about their experience staying at the hotel are mostly women from abroad. Through the sentiment analysis, “Housekeeping” was determined as the most important factor of the overall hotel experience. On the other hand, the largest share of negative particles was determined for the „Other hotel services“, therefore this factor has the greatest negative impact on the eWoM of hotel guests. Contribution - This research contributes to reducing the existing gaps in the literature on hotel experience, by identifying factors that have a negative impact on the eWoM of hotel guests. The findings of this study also provide practical implications based on which hoteliers can improve their strengths and weaknesses in the existing elements of the hotel offer.
Portfolio Analysis Using Malaysia Stock Market Data: Before and During COVID-19 Pandemic
Authors: Khah May She , Wei Yeing Pan
Published: January 2023

This study attempts to evaluate Malaysia’s stock performance before and during COVID-19 across all sectors by using the Sharpe ratio and Sortino ratio with risk measured by standard deviation. We develop an algorithm for stock selection to construct the portfolio investment. In our study, we apply the Sharpe ratio, Treynor ratio and Jensen’s alpha to identify the optimal portfolio. The result shows that the portfolio with stock selection based on the Top 20 Sortino ratio from all stocks is superior to stock selection based on the Top 3 Sortino ratio for each sector. The daily adjusted closing stock prices are collected from March 1, 2019 to December 31, 2021. The result of this study indicates that several sectors are not affected during the COVID-19 pandemic, which are Technology, Industrial, Consumer Products and Services and Property. Hence, investors are suggested to form an optimal portfolio investment based on these sectors. Stock analysts are recommended to imply various risk-adjusted measures to evaluate the portfolio performance with a comprehensive perspective to support the outcome analysis.
Peningkatan Kapasitas Pemahaman Warga Desa Melung Terhadap Pemasaran Melalui Internet
Authors: Masykuroh Kholidiyah , Athiyah Ummi , Hikmah Irmayatul , Wijaya Andreas Rony
Published: January 2023

Internet merupakan hal penting yang tidak terelakkan lagi, baik di perkotaan maupun di pedesaan. Masyarakat cenderung membutuhkan internet untuk memenuhi kebutuhan sehari-hari baik itu sebagai media komunikasi melalui jaringan komunikasi elektronik maupun sebagai media pemenuhan mata pencaharian pokok. Desa melung merupakan desa wisata dan memiliki banyak UMKM yang dikelola oleh masyarakat desa. Masyarakat Desa Melung memiliki permasalahan yaitu belum memiliki pemahaman mengenai pemanfaatan internet secara maksimal terutama dalam hal melakukan pemasaran untuk desa wisata dan pemasaran produk UMKM masyarakat. Belum maksimalnya pemahaman warga desa melung dalam memanfaatkan internet serta kurangnya pemahaman warga mengenai internet terutama dalam hal pemasaran, melatar belakangi kegiatan sosialisasi dalam pengabdian masyarakat ini. Metode yang digunakan adalah workshop, dengan materi mengenai literasi teknologi, pengenalan internet, dan internet marketing. Berdasarkan kegiatan yang telah dilakukan dan juga hasil survei, diperoleh kesimpulan bahwa pemahaman masyarakat sesudah dilaksanakan workshop menunjukan baik sekali, ditunjukan dengan nilai rata-rata pemahaman 4.3 dari skala 1-5 dan terjadi peningkatan pemahaman peserta tentang pemasaran menggunakan internet ditunjukan dengan kenaikan persentase kenaikan pemahaman masyarakat berkisar dari 10 – 24 % dan rata-rata peningkatan sebesar 17.2%, peningkatan persentase terkecil yaitu pada pernyataan ketiga sebanyak 10% tentang keaktifan masyarakat dalam menggunakan internet, sedangkan peningkatan persentase terbesar pada penyataan keempat sebanyak 24% tentang pemahaman internet dapat digunakan dalam proses pemasaran. Dengan demikian, warga masih perlu diberikan sosialiasi dan pelatihan mendalam  sehingga masyarakat Desa Melung dapat menggunakan internet untuk pemasaran
Solve the 3x+1 Problem by the Multiplication and Division of Binary Numbers
Authors: Feng Jishe
Published: January 2023

The 3x+1 problem asks the following: Suppose we start with a positive integer, and if it is odd then multiply it by 3 and add 1, and if it is even, divide it by 2. Then repeat this process as long as you can. Do you eventually reach the integer 1, no matter what you started with? Collatz conjecture (or 3n+1 problem) has been explored for about 85 years. In this paper, we convert an integer number from decimal to binary number, and convert the Collatz function to binary function, which is multiplication and division of two binary numbers. Finally the iternation of the Collatz function, eventually reach the integer 1, thus we solve the 3x+1 problem completely.
Therapeutic Properties of Polyphenols Affect AMPK Molecular Pathway in Hyperlipidemia
Authors: Sotoudeheian Mohammadjavad , Hoseini SeyedAhmad , Mirahmadi Seyed-Mohamad-Sadegh
Published: January 2023

Hyperlipidemia is the fat particles excess in the serum. Hyperlipidemia increases the mortality rate that occurs with other metabolic disorders. Hyperlipidemia is classified into familial and acquired subgroups. Moreover, Hyperlipidemia etiology is based on environmental or genetic factors. For instance, abnormal HMG-CoA regulation down-regulates ubiquitin ligase and targets variable oxidative stress-related condition proteins. There has been proven reactive oxygen species (ROS) overshoot happens during hyperlipidemia occurrence. OS, directly and indirectly, regulates molecular cascades within the cell and leads to gene expression alteration. At this molecular juncture, AMPK is affected by ROS. AMPK is a serine-threonine kinase and a critical energy balance. Low energy conditions result in AMPK activation due to the down-regulation of protein and lipid synthesis. Furthermore, ER stress and activated unfolded protein proteasomal response and autophagy are AMPK mediated. Polyphenols are widespread dietary plant-based compounds that regulate gene expression and signal conduction. Through the hyperlipidemic state, FFAs releasing indirectly connect to AMPK/NF-κB pathway then polyphenols target them. AMPK, during this FFA exposure, down-regulates de novo lipid molecules generation. Likewise, if AMPK/mTOR pathway failure is prolonged, the hyperlipidemic state may be explicit, activated by natural herbal mediators, e.g., polyphenols. Polyphenols activate the AMPK signaling pathway and influence lipid metabolism. Polyphenol-mediated AMPK activation results in lipogenesis inhibition and lipophagy. Cholesterol efflux mediated polyphenols lipid-lowering effects, accessing LXR pathway. All these clues persist on direct or indirect AMPK-related polyphenolic anti-hyperlipidemic effects.
Application of Drifted Pumice Stone as a Sand-Capping Material
Authors: Inoue Tetsunori , Fujita Isamu
Published: January 2023

Large amounts of pumice stone generated by the submarine volcanic eruption at Fukutoku Okanoba on August 13, 2021, drifted ashore, affecting ship navigation and fishery operations. Through laboratory experiments, we investigated the possibility of using pumice as a sand-capping material for eutrophic sediments. Crushed pumice as a sand cover material effectively reduced the sedimentary oxygen consumption rate. Nutrient release from sediment showed a similar trend, with ~25% and 82% reduction in NH4-N and PO4-P release rates, respectively. Furthermore, the bivalve exposure experiments using crushed pumice suspended in seawater showed no adverse effects specific to pumice and lower bivalve mortality than that using kaolin at the same concentration. This could be owing to differences in gill accumulation and blockage owing to the particle size variation of the suspended particles. These results suggest that crushed pumice is effective for sand covering and suppresses oxygen consumption and nutrient release from the sediments.
Role of Impaired Astrocyte Gap Junction Coupling in Epilepto-Genesis
Authors: Bedner Peter , Steinhäuser Christian
Published: January 2023

The gap junction-coupled astroglial network plays a central role in the regulation of neuronal activity and synchronization, but its involvement in the pathogenesis of neuronal diseases is not yet understood. Here we present the current state of knowledge about the impact of impaired glial coupling in the development and progression of epilepsy and discuss whether astrocytes represent alternative therapeutic targets. We focus mainly on temporal lobe epilepsy (TLE), which is the most common form of epilepsy in adults, characterized by high therapy resistance. Functional data from TLE patients and corresponding experimental models point to a complete loss of astrocytic coupling, but preservation of the gap junction forming proteins connexin43 (Cx43) and connexin30 (Cx30) in hippocampal sclerosis. Several studies further indicate that astrocyte uncoupling represents a causal event in the initiation of TLE, as it occurs very early in epileptogenesis, clearly preceding dysfunctional changes in neurons. However, more research is needed to fully understand the role of gap junction channels in epilepsy and to develop safe and effective therapeutic strategies targeting astrocytes.
Improving Deep Echo State Network with Neuronal Similarity-based Iterative Pruning Merging Algorithm
Authors: Shen Qingyu , Zhang Hanwen , Mao Yao
Published: January 2023

Recently, a layer-stacked ESN model named deep echo state Network (DeepESN) has been established. As an interactional model of recurrent neural network and deep neural network, investigations of DeepESN are of significant importance in both areas. Optimizing the structure of neural networks remains a common task in artificial neural networks, and the question of how many neurons should be used in each layer of DeepESN must be stressed. In this paper, our aim is to solve the problem of choosing the optimized size of DeepESN. Inspired by the sensitive iterative pruning algorithm, a neuronal similarity-based iterative pruning merging algorithm (NS-IPMA) is proposed to iteratively prune or merge the most similar neurons in DeepESN. Two chaotic time series prediction tasks are applied to demonstrate the effectiveness of NS-IPMA. The results show that the DeepESN pruned by NS-IPMA outperforms unpruned DeepESN with the same network size, and NS-IPMA is a feasible and superior approach to improving the generalization performance of DeepESN.
Placental Mitochondrial Function and Dysfunction in Preeclampsia
Authors: Jahan Fahmida , Vasam Goutham , Green Alex E , Bainbridge Shannon A , Menzies Keir J
Published: January 2023

The placenta is a vital organ of pregnancy, regulating adaptation to pregnancy, gestational-parent/fetal exchange and ultimately fetal development and growth. Not surprisingly, in cases of placental dysfunction - where aspects of placental development or function become compromised - adverse pregnancy outcomes can result. One common placenta-mediated disorder of pregnancy is preeclampsia (PE), a hypertensive disorder of pregnancy with a highly heterogeneous clinical presentation. The wide array of clinical characteristics observed in pregnant individuals and neonates of a PE pregnancy are likely the result of distinct forms of placental pathology underlying the PE diagnosis, explaining why no one common intervention has proven effective in the prevention or treatment of PE. The historical paradigm of placental pathology in PE highlights an important role for utero-placental malperfusion, placental hypoxia and oxidative stress, and a critical role for placental mitochondrial dysfunction in the pathogenesis and progression of the disease. In the current review, the evidence of placental mitochondrial dysfunction in the context of PE will be summarized, highlighting how altered mitochondrial function may be a common feature across distinct PE subtypes. Further, advances in this field of study and therapeutic targeting of mitochondria as a promising intervention for PE will be discussed.
A Review on the Comprehensive Phylogenetic Relationship among Indian Species of Drimia: An Ethno-medicinal Indigenous Crop from Tribal Forest Belt
Authors: Shit Vivek , Kumar Manoj
Published: January 2023

Indian Tribal population is known for their self-sustainability, including their robust natural health and trivial lifestyle, further traditionally relied on medicinal plants throughout history. The evolutionary history of the ethnic-medicinal bulbous geophyte has long been a contention in monocot systematics. In India, the genus is represented by a species array. Moreover, the phylogeny delimitation amongst them is poorly defined to date. Phenolics, sterols, proteins and some other phytochemicals of Drimia have also been isolated for pharmacological and clinical studies that have strongly recommended their background effect of geographical positioning. Through several in vivo and in vitro studies, extracts derived from Drimia species demonstrated biological activity, including antifungal antibacterial, antiviral, anti-inflammatory antioxidant, and insecticidal properties. This review highlights the comprehensive phylogenetic analysis of Indian spp. of Drimia and the multi-omics-based approach for species delineation, the discovery of candidate genes and the development of plant-based drugs, as well as the long-term utilisation of plant pharmaceutical resources.
Associations of Passive Drinking with Perceived Health Status, Mental Health, and Family Wellbeing in Hong Kong Chinese Adolescents: A Cross-Sectional Study
Authors: Chau Siu Long , Wu Yongda , Wang Man Ping , Ho Sai Yin
Published: January 2023

Background: Passive drinking is prevalent in adolescents worldwide, but its prevalence and harm are understudied. Methods: Secondary students (n=5840, grades 7-12) from 23 selected schools in Hong Kong participated in the survey from 2015-16. Students reported the harm of passive drinking, perceived health status, Patient Health Questionnaire-2, Perceived Stress Scale-4, perceived happiness, family health, happiness, and harmony in the questionnaire. The associations were analyzed using multivariable logistic regression (odds ratio, OR) and linear regression (unstandardized coefficient, b), adjusted for confounders. Results: 29.1% (95% CI 27.8 to 30.5%) of students experienced passive drinking in the past 30-day. Past 30-day parental passive drinking was associated with a higher level of depressive symptoms (AOR 1.63, 95% CI 1.26 to 2.10), stress (adjusted b 0.76, 0.42 to 1.10), and lower level of perceived happiness (adjusted b -0.52, -0.72 to -0.33). Past 30-day parental passive drinking was associated with a lower level of family health (adjusted b -1.39, 95% CI -1.66 to -1.11), family happiness (adjusted b -1.36, -1.64 to -1.08), and family harmony (adjusted b -1.40, -1.70 to -1.10). Conclusion: Passive drinking was associated with poorer mental health, family wellbeing, and lower level of happiness among Hong Kong Chinese adolescents.
The Effect of Primary School Education on Preventive Behaviours During COVID-19 in Japan
Authors: Yamamura Eiji , Tsutui Yoshiro , Ohtake Fumio
Published: January 2023

Childhood hygiene education has resulted in individuals engaging in hand washing and mask wearing to cope with COVID-19. Individuals can form sustainable development-related habits through childhood education.
Assessing Completeness of OpenStreetMap Building Footprints Using a Gamification Approach in MapSwipe
Authors: Ullah Tahira , Lautenbach Sven , Herfort Benjamin , Schorlemmer Danijel
Published: January 2023

Natural hazards threaten millions of people all over the world. To address the risk, exposure and vulnerability models with high resolution data are essential. However, in many areas of the world, exposure models are rather coarse and aggregated over large areas. Although OpenStreetMap (OSM) offers great potential to assess risk at a detailed building-by-building level, completeness of OSM building footprints is still heterogeneous. We present an approach to close this gap by means of crowdsourcing based on the mobile App MapSwipe, where volunteers swipe through satellite images of a region collecting user feedback on classification tasks. For our application, MapSwipe was extended by a completeness feature that allows to classify a tile as “no building”, “complete” or “incomplete”. To assess the quality of the produced data, the completeness feature was applied at four regions. Our results show that the crowdsourced approach yields a reasonable classification performance of the completeness of OSM building footprints. Nevertheless, this study also revealed that volunteers tend to classify nearly completely mapped tiles as “complete”, especially in areas with a high OSM building density. Another factor that influenced the classification performance was the level of alignment of the OSM layer with the satellite imagery.