bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Independensi, Kompetensi dan Gaya Kepemimpinan Terhadap Kinerja Auditor Internal Pemerintah
Authors: Nasution Soraya Annisa , Agustiawan Agustiawan , Anriva Della Hilia
Published: August 2023

This research aims to analyze partially and simultaneously the effect of independence, competence, and leadership style on the performance of the government’s internal auditors at Badan Pengawas Keuangan dan Pembangunan (BPKP) and the Inspectorate of Riau Province. This research is a quantitative descriptive type. The data source used is primary data. Data was collected by survey approach using a questionnaire method. The population in this research were all auditors at BPKP and the Inspectorate of Riau Province. The research sample is the entire population used in the study. Sampling was carried out using the saturated/census sampling method. The analytical technique used is multiple linier regression analysis and processed using SPSS 25 version software. The partial result shows that independence has no significant effect on auditor performance, competence has a significant effect on auditor performance and leadership style has a significant effect on auditor performance.Keywords: Independence, Competence, Leadership style, Auditor performance
Cause and Impact Analysis of Homeless and Beggars: A Study of Urban Poverty and Social Stigma in Medan
Authors: Benediktus Redemptus , Meritus Dionisius
Published: August 2023

This study proposes an in-depth analysis of the factors causing and impacting the phenomenon of homeless people and beggars in the city of Medan. The aim of the research is to identify the root causes as well as the social consequences of these problems in the urban context. Research methods include qualitative and quantitative data analysis, including interviews with the individuals involved, community surveys, and related statistical analyses. The results of the analysis show that high unemployment rates and economic inequality are central factors in pushing individuals towards a state of homeless people and beggars. Limited access to education and health services also plays an important role in maintaining this problem. Social factors, such as family problems and violence, also have a large impact on individual conditions. The impact of the problem of homeless people and beggars includes higher physical and mental health risks, as well as social stigmatization that hinders community reintegration efforts. The existence of homeless people and beggars can also affect the city's image, security, and economic aspects. By understanding the root of the problem and its impact, it is hoped that this research will contribute to efforts to reduce homeless people and beggars in Medan City and develop a more inclusive and caring society
Filament Eritme Yöntemiyle Üretilen PA12 ile Ticari PA12’nin Morfolojik, Termal ve Mekanik Özelliklerinin Karşılaştırılması
Authors: TAŞDEMİR Münir , BEKTAŞ Serbay
Published: August 2023

Polimer malzemeler, dünya ekonomisinin çeşitli alanlarında yaygın olarak kullanılmakta ve özellikleri hızla gelişmektedir. Eklemeli imalat (Eİ) gibi yeni teknolojilerin ortaya çıkışı, polimer malzemeler ve kompozitler için daha yüksek performans ve işlevsellik gibi ihtiyaçlar doğurmuştur. Polimer toz malzemeler, Eİ teknolojilerinde en çok kullanılan sarf malzemelerindendir ve ağırlıklı olarak seçici lazer sinterleme (SLS) teknolojisinde kullanılır. SLS, birbirini izleyen toz hammadde katmanlarını 3 boyutlu (3B) bilgisayar destekli tasarım modeline göre seçici olarak sinterleyerek 3B katı bileşenleri üreten bir toz yatağında füzyon işlemidir. Bu çalışmada; Poliamid 12 (PA12), fiber eritme yöntemi kullanılarak toz halinde üretilmiş ve masaüstü SLS sistemlerde kullanılmak üzere optimize edilmiştir. Yapılan çalışmada PA12, eriyik eğirme cihazında farklı çaplarda fiber iplikler haline getirilmiştir. Elde edilen fiber iplikler kesilerek ısıtıcılı balon karıştırıcı içinde Polietilen Oksit (PEO) ile termal işleme tabi tutulmuş ve küresel forma yakın tozlar elde edilmiştir. Kurutma ve eleme işlemlerinden geçirilen bu tozlarla, açık parametreye sahip bir SLS (Seçici lazer sinterleme) 3B yazıcıda baskı alınmıştır. Toz numunelerine diferansiyel taramalı kalorimetri (DSC), taramalı elektron mikroskobisi (SEM) ve elek analizi yapılmıştır. Baskı numunelerine ise; çekme, sertlik, darbe, yoğunluk, ergime akış indeksi (EAİ), vicat yumuşama sıcaklığı testleri yapılmıştır ve numunelerin mikroyapı incelemesi için SEM analizi kullanılmıştır. Numunelerin testlerin sonuçları incelenerek ticari ve üretilen PA12’nin özellikleri karşılaştırılmıştır.
Basınç Altında Soğutulan Sıvı Pd Elementinin Mikro Yapısal Gelişiminin Moleküler Dinamik Benzetimi ile İncelenmesi
Authors: KAZANÇ Sefa
Published: August 2023

Bu çalışmada sıvı fazdan farklı basınç değerleri altında hızlı soğutulan hacimsel (bulk) yapıdaki Paladyum (Pd) sisteminde meydana gelen mikro yapısal gelişimler Moleküler Dinamik (MD) yöntemi ile incelendi. Atomlar arasındaki etkileşme kuvvetleri çok cisim etkileşmelerini içeren Embedded Atom Metodu (EAM) kullanılarak hesaplatıldı. Model sistem içerisinde mikroyapısal değişimlerin belirlenmesi için radyal dağılım fonksiyonu (RDF), voronoi çok yüzlü analizi (VP), katlı simetrilerin belirlenmesi, küresel periyodik düzen (SPO) ve genel komşu analizi (CNA) yöntemlerinden yararlanıldı. Sıvı Pd sistemine 0-40 GPa aralığında uygulanan basınç değerleri için 1x1014 K/s soğutma hızında camsı yapı, 1x1013 K/s soğutma hızında ise kristal yapı dönüşümleri gözlendi. Ayrıca bu dönüşümlerin gerçekleştiği camsı ve kristal geçiş sıcaklıkları hesaplandı. Soğutma işlemleri sonucu elde edilen camsı yapılarda ikosahedral benzeri kısa mesafe düzenli kümeli yapıların, baskın çok yüzlü yapılar oldukları tespit edildi.
Salda Gölü Hidroloji Parametrelerinin Değerlendirilmesi
Authors: DAVRAZ Ayşen , AKSEVER Fatma
Published: August 2023

Salda Gölü doğal güzelliği ve stramatolit oluşumları ile dünyadaki ender alkali göllerden birisidir. Salda Gölü’nün beslenimi göl yüzeyine ve alt havza geneline düşen yağışlar, mevsimlik ve sürekli akan dereler ile yeraltısuyu akımı ile sağlanmaktadır. Salda Gölü için yağıştan beslenim miktarı 21.95 x 106 m3/yıl’dır. Gölün boşalımı ise sadece buharlaşma ile gerçekleşmekte olup göl alanından buharlaşma miktarı 51.96 x106 m3/yıl olarak hesaplanmıştır. Salda Gölü su seviyesinin Eylül-2015’den itibaren sürekli düştüğü ve Ocak-2022’ye kadar düşüm miktarının 3.17 m olduğu belirlenmiştir. Salda Gölü çevresinde gölü besleyen çok sayıda su kaynağı bulunmaktadır. Bu kaynaklarda Mayıs 2021-2022 arasında yapılan debi ölçümlerine göre, göle ortalama 0.286 m3/s beslenim olacağı öngörülmektedir. Salda Gölü havzasında en önemli akifer alüvyon olup bu birimde açılmış çok sayıda sondaj kuyusu bulunmaktadır. Şubat-2021 ve Ekim-2022 tarihleri arasında kuyulardan seviye ölçümleri yapılmıştır. Havzada statik seviye Salda köyü çevresinde 0.5-4.85 m ve Yeşilova’da 13.27-21.15 m olarak tespit edilmiştir. Havzada yeraltısuyu akım yönü Salda Gölü'ne doğrudur. Salda Gölü çevresinde geniş alanlarda yüzeyleyen Marmaris peridotiti birimlerinden de yüzeyaltı akışı ile göle yeraltısuyu beslenimi gerçekleşmektedir. Bu beslenim Salda Gölü suyunun hidrojeokimyasal özelliklerini denetleyen en önemli unsurdur. Bu çalışmada, göl seviye değişimini denetleyen hidrolojik parametreler ve bunların etkileri irdelenmiştir. Salda Gölü çevresinde bulunan meteoroloji istasyonlarından alınan yıllık yağış verileri ile göl seviyesindeki dalgalanmalar incelendiğinde yağış miktarının Salda Gölü seviye değişimini denetleyen en önemli parametre olduğunu görülmektedir. Buharlaşma etkisi ise daha azdır.
Dinamik Termokimyasal Yöntem ile Si3N4/SiC Kompozit Tozunun Üretilmesi
Authors: ARSLAN Betül , ERKEN Nazlı , CANIKOĞLU Nuray
Published: August 2023

Bu çalışmada, silisyum nitrür/silisyum karbür (Si3N4/SiC) kompozit tozu, 2 adımlı dinamik termokimyasal yöntem ile azot ve argon atmosferlerinde silisyum oksit ve karbonun reaksiyonuyla sentezlenmiştir. Bu amaçla farklı reçeteler hazırlanmış olup nitrürlenme ve karbürlenme sıcaklıkları (1400, 1450 ve 1500°C) ile işlem süresi (1 ve 2 saat) üzerine çalışmalar yapılmıştır. Öncelikle farklı reçeteler FactSage programı yardımıyla termodinamik olarak incelenmiştir. Uygun olabilecek reçeteler belirlendikten sonra hammadde karışımları, SiO2 ve karbon siyahı kullanılarak C/SiO2 oranı 2.25 ve 3 olacak şekilde hazırlanmıştır. Toz karışımlarından elde edilen granüllere uygulanan termokimyasal işlemler sonrasında kompozit toz üretimi için en optimum sonuç, 1450°C’de 2 saat N2 atmosferinde nitrürleme ve 1450°C’de 1 saat Ar atmosferinde karbürleme işlemleriyle 4 rpm dönme hızında sağlanmıştır. Üretilen tozların mikroyapı ve faz incelemeleri SEM-EDS ve XRD yöntemleriyle gerçekleştirilmiştir.
Classification of T-ALL, B-ALL and T-LL Malignancies Using Adaptive Network-Based Fuzzy Inference System Approach Combined with Nature-Inspired Optimization on Microarray Dataset
Authors: AKALIN Fatma , YUMUŞAK Nejat
Published: August 2023

Leukemia is the formation of cancer with different characteristic findings. According to the progress type of disease in the body is called acute or chronic. Acute leukemias are characterized by the presence of blast cells that proliferate uncontrollably in the bone marrow and then go into the blood and tissues. Determination of T/B or non T/B cell class is important in the immunophenotypic evaluation related to subtypes of blast cells. Because the diagnosis and treatment processes of B-ALL, T-ALL and T-LL subtypes, which are composed of B and T cell lines, are different. Therefore, correct diagnosis is vital. In this study, the molecular diagnosis was provided for the accurate detection of T-ALL, B-ALL and T-LL subtypes through microarray datasets. But, microarray datasets have a multidimensional structure. Because it contains information related to the disease as well as information not related to the disease. This situation also affects the training situation and computational cost of the model. For this, the whale optimization algorithm was used in the first stage of the study. Thus, related genes were selected from the data set. Secondly, the selected potential genes were given as input to the ANFIS structure. Then, in order to improve the inference power, parameter optimization related to the membership function of the ANFIS structure was provided with ABC and PSO optimization algorithms. Finally, the predictions obtained from the ANFIS, ANFIS+ABC, and ANFIS+PSO methods for each sample were classified using the logistic regression algorithm and, an accuracy rate of 86.6% was obtained.
Lightning Squad: Assessing the Dosage Effect of Computer-Assisted Tutoring with Cooperative Learning for Struggling Readers
Authors: Wang Xue , Neitzel Amanda Jean , Madden Nancy
Published: August 2023

This quantitative study examines the dosage effect of a computer-assisted tutoring approach, tutoring with the Lightning squad, on the reading achievement of struggling students. Using a multi-site, cluster-randomized controlled trial design, 188 students in Grades 1-3 from six schools in Minnesota and Virginia were randomly assigned to receive either Lightning squad tutoring or regular reading instruction between November 2016 and January 2017. Implementation results revealed that many students in the treatment group did not receive the full intended dosage of treatment. Dosage analyses indicated that high attendance in the intervention had a significant positive effect on read- ing outcomes, including passage Comprehension and Word attack. the findings emphasized the critical role of implementation fidelity in pro- gram effectiveness and suggested that a higher dosage of the Lightning squad intervention may lead to better outcomes for struggling readers.
Dissecting team reflexivity, a prospective observation-based study : effects of content and quality of reflexivity on resuscitation performance in ad-hoc medical teams
Authors:   , Morgenthaler Camille
Published: August 2023

This dissertation focuses on two studies investigating a self-led between task reflexivity intervention between two simulated resuscitation tasks. We will begin with a theoretical introduction about the reflexivity process and its effects. We will also position reflexivity in relation the challenges faced by healthcare teams. We then present the two papers at the core of this dissertation. The two papers focus on cardiopulmonary performance improvement, content of reflexivity session, adherence to resuscitation algorithm in the resuscitation phases and discussed during reflexivity, and finally quality of reflexivity. Results of both papers show that a short self-led reflexivity intervention help teams to improve their resuscitation performance. Analyses of the reflexivity process itself allowed to demonstrate that our participants engaged in the reflexivity process and followed the instructions. Quality (especially scope of reflection) impacts performance improvement. In the discussion, we address perspectives and limitations.
Coordination processes in conversation : the cases of gaze in greetings and storytelling in teaching
Authors:   , Tilston Ottilie
Published: August 2023

Throughout human evolution, face-to-face conversational interaction has been the primary means of communication in everyday life. It is the fundamental setting for human interaction and so ideal to gain insights into the nature of communication (Schegloff, 2007). Humans communicate primarily to solve problems of cooperation, and these cooperation problems are a source of evolutionary pressure that has shaped the nature of social interaction. This thesis focuses on the cases of two recurrent coordination problems in communication, and the behavioural adaptations specialised to resolve them. One recurrent interactional problem we face is how to begin face-to-face social interactions (Pillet-Shore, 2018). Contrary to what we might first think, social interactions do not begin by people simply starting to speak, instead they must engage with each other methodically through a combination of verbal and non-verbal cues in order to get into the interaction (Mondada et al., 2020). Gaze is specialised during greeting behaviour to solve this problem by initiating social interaction. Another recurrent interactional problem faced by all human cultures is passing on information and skills to prevent them from dying out from one generation to the next. This is commonly achieved through the social activity of teaching (Kline, 2015), particularly through the specialised teaching method of storytelling (Scalise Sugiyama, 2017). The cases of gaze in greetings and storytelling in teaching illustrate how humans have adapted to facilitate social interaction, providing broad insight into coordination processes in communication.
Suatu Analisis Regresi pada Dampak Promosi terhadap Keputusan Pembelian Konsumen Tokopedia pada Era Revolusi Industri 4.0.
Authors: Masruchiyah Nieke , Ardi Saeful , Astuty Pudji
Published: August 2023

Penelitian ini bertujuan untuk mengetahui pengaruh promosi terhadap keputusan pembelian konsumen di Tokopedia pada era revolusi industri 4.0. Responden dan sampel yang digunakan berjumlah 101 responden. Metode yang digunakan dalam penelitian ini adalah metode kuantiatif dengan skala likert. Data yang digunakan adalah data primer dengan sampel sebanyak 101 responden dan menggunakan. analisis yang digunakan adalah regresi linier berganda dan Moderated Regression Analysis (MRA) diolah dengan  bantuan SPSS versi 26. Hasil penelitian ini menunjukan bahwa Variabel promosi tidak berpengaruh signifikann terhadap keputusan pembelian. Kesimpulan penelitian ini yaitu di harapkan tokopedia mampu meningkatkan promosi, memotivasi konsumen untuk memberikan ulasan dan memberikan harga lebih kompetitif dari marketplace lainnya dan dan memaksimalkan teknologi di era revolusi industri 4.0 untuk menarik daya beli konsumen dan tujuan perusahaan, serta mendaptkan konsumen lebih banyak lagi ditengah persaingan yang semakin ketat.
REFLEXÕES ACERCA DO PODER DE DECISÃO DA PESSOA TRANS SOBRE REALIZAR A CIRURGIA DE AFIRMAÇÃO DE GÊNERO
Authors: Passos Taciana Silveira , Almeida-Santos Marcos Antonio , Cordero-Ramos Nuria
Published: August 2023

Trata-se de uma reflexão sobre os discursos médicos que descrevem as experiências ou regulamentam a cirurgia de afirmação de gênero (CAG). Para isso, trabalhou-se com os pressupostos teórico-metodológicos de análise do discurso foucaultiano. Foi utilizada como técnica de pesquisa a análise documental de artigos científicos, manuais e normas de saúde. Evidenciou-se que o discurso médico trata a experiência trans como algo que hegemonicamente necessita de “conserto” cirúrgico para melhoria da qualidade de vida. Não há dúvidas sobre a importância médica e social da alternativa cirúrgica para aqueles que a desejam, no entanto, questiona-se aqui a forma como “vende-se” a ideia do processo transexualizador como ideário de resolutividade ao fenômeno da transexualidade. Em alguns discursos, omite-se a ideia de que a expectativa de melhoria da disforia de gênero após CAG pode ser um processo frustrante. As avaliações após CAG ainda não trouxeram evidências homogêneas de melhorias significativas nos aspectos relacionados à qualidade de vida. Além disso, antes da publicação da resolução CFM 2.265/2019, os indivíduos não considerados pelo “gatekeeper” como “verdadeiramente” trans, eram excluídos desse processo. Foram encontrados discursos que reforçam a ideia de gênero hegemônico ao determinar que a pessoa “normal” é aquela que possui coerência entre sexo, gênero e sexualidade. Portanto, há um descompasso entre os avanços nas nomenclaturas e o discurso médico que ainda reforça a patologização da transexualidade, quando fundamenta ideais normativos binários.
An Efficient and Easy-to-Implement Method for SLL Reduction in RIS-Aided Systems
Authors: Haskou Abdullah , Khaleghi Hamidreza
Published: August 2023

Reconfigurable Intelligent Surfaces (RISs) are being considered as a potential technology for upcoming 6G cellular communication systems. RISs offer the capability to steer a wireless signal in a desired direction, thereby enhancing the overall performance of wireless systems in terms of coverage and spectral efficiency. However, the conventional methods of RIS beamforming result in significant inter-beam interference primarily caused by relatively high Side Lobe Levels (SLLs). In antenna beamforming, amplitude tapering has shown promising results in Multi-User Multiple-Input Multiple-Output (MU-MIMO) systems. Amplitude tapering allows for a notable reduction in inter-beam interference by decreasing SLLs, albeit at the expense of a reduction in the Main Lobe Level (MLL) and an increase in its width. In this paper we investigate the feasibility of utilizing this technique for RIS beamforming. In addition, we demonstrate the effectiveness of this technique through link-level simulations of a RIS-aided multi-user downlink system.
The vascular structure of the urethra: a historical overview
Authors: Natale Gianfranco , Armocida Emanuele
Published: August 2023

Penile structure and function aroused interest since ancient times, when the erectile activity was mainly attributed to an accumulation of air by Greek and Roman physicians. In the Renaissance period Leonardo da Vinci was one of the first to recognize the right functional importance of the presence of blood in penile tissues. Since then, although with different techniques and interpretations, the morphological studies reported the description of blood vessels differently arranged in complicated networks. The discovery of blood circulation by William Harvey in his famous Exercitatio anatomica de motu cordis (1628) and the demonstration of capillaries by Marcello Malpighi stimulated a deeper research. In particular, the presence of a non vascular spongy tissue (cavernous bodies) with cellular texture (cellular theory) was postulated and interpreted as consisting of a loose and elastic spongy tissue arranged in several cells into which, during erection, blood is poured from the arteries, and from which it is afterwards removed by veins. In the beginning of the 19th century, when both vascular and cellular texture theories concerning the penile anatomy were still coexisting, a particular attention was paid to the urethral structure. Thanks to improved injection techniques, Paolo Mascagni and Alessandro Moreschi provided accurate works on this subject, demonstrating the vascular nature of the cavernous bodies. Finally, in 1899 Victor Vecki von Gyurkovechky confirmed the vascular theory, histologically demonstrated by the presence of endothelium.
“De oculis”, a chapter on ocular anatomy by Constantinus Africanus
Authors: Hogewind Barend F. , Hogewind Françoise E. I.
Published: August 2023

Purpose: The publication of the compendium Pantegni by Constantinus Africanus in the monastery of Monte Cassino in the eleventh century CE was a pivotal moment in the history of medicine in Western Europe. The work is predominantly based on the Liber regalis by Haly Abbas (Baghdad, tenth century CE). The earliest available manuscript of the Pantegni (KB 73 J6) is handwritten and has been supervised by Constantinus himself. It includes a chapter on ocular anatomy. In this paper we try to distill the anatomic description by Constantinus.

Methods: The chapter “de oculis” on ocular anatomy as found in chapter 13 of book 3 in KB 73 J6 is interpreted in the historical context and translated into Modern English.

Results: We present an English translation of the concerning chapter.

Conclusion: Constantinus bequeathed a compact but comprehensive account of the anatomy of the eye, which can be rendered into a contemporary representation with use of the historical context.
Anatomy and Ceroplastic School in Bologna: a heritage with unexpected perspective
Authors: Manzoli Lucia , Ratti Stefano , Cocco Lucio
Published: August 2023

Ceroplastic, the art of wax modelling, is a depiction mode that has been used widely throughout time for artistic, religious and social purposes. During the 16th Century, ceroplastic became also an essential tool for medical education thanks to the creation of the first anatomical wax models. For centuries, anatomists have worked with artists with the aim of producing faithful and long-lasting wax artefacts that reproduce physiological and/or pathological conditions. Important figures such as Ercole Lelli and Anna Morandi Manzolini refined the techniques of the anatomical wax modelling and created works that are to date preciously conserved. The scientific and didactic value of these works was indisputable, for wax anatomical models have deeply facilitated the education of medical students in that time. Nowadays, a similar impact on medical education is given by new technologies such as augmented reality, that allows the addition of virtual contents to tangible anatomical 3D models. Under this light, anatomical wax models and augmented reality can be compared as two innovative tools that have changed the history of anatomical teaching.
An anthropological and paleopathological analysis of a peculiar skeleton from the Necropolis of Zancle (1st century BCE – 1st century CE): a case report
Authors: Fiorentino Claudia , Miccichè Roberto M. , Sìneo Luca
Published: August 2023

The work presents the results of the anthropological and paleopathological analysis carried out on human skeletal remains of an individual (T-173) found in a burial from the necropolis “sector 96”, Messina, Sicily, dating back to the Roman Empire (1st century BCE – 1st century CE). The study aimed to acquire the information necessary for the reconstruction of the biological profile. In fact, T173 is an adult male which is particularly interesting from a paleopathological point of view, showing skeletal anomalies from the cranial to the post-cranial skeleton probably caused by variations of genetic, neoplastic, articular and dental nature. Furthermore, the analyses have highlighted the possible cause of death, related to two perimortem traumatic lesions on parietal bones.
Role of extracellular vesicles derived by human gingival mesenchymal stem cells in cardiomyocytes acute hypoxia
Authors: Della Rocca Ylenia , Pizzicannella Jacopo , Marconi Guya Diletta , Fonticoli Luigia , Trubiani Oriana , Diomede Francesca
Published: August 2023

Hypoxia has an impact on pathological conditions of different tissues and especially on the heart where it can have different consequences depending on the duration of exposure to the hypoxic state. Acute hypoxic exposure can result in reversible acclimatization in heart tissue, maintaining a good systemic oxygen supply, while chronic hypoxic exposure leads to tissue damage exacerbating hypoxia-induced cardiac dysfunction. Extracellular vesicles (EVs) are small membrane vesicles, of the order of nanometers, secreted by different cell types. EVs are mediators of intercellular communication in both physiological and pathological conditions. EVs produced by oral-cavity-derived Mesenchymal Stem Cells (MSCs), including human gingival mesenchymal stem cells, have pro-angiogenic and anti-inflammatory effects. For this reason, the EVs can be identify as a new therapeutic potential for tissue regeneration. The aim of the present work was to evaluate the effect of treatment with EVs produced by human gingival mesenchymal stem cells (hGMSCs) on an in vitro model of HL-1 cardiomyocytes cultured under acute hypoxia state (0,2% hypoxia) followed by normoxia conditions. The HIF-1α expression was downregulate with EVs treatment. EVs could represent an innovative platform to prevent the hypoxic damages.
Circulating endothelial cells and endothelial-derived vesicles identification in patients with infantile hemangioma: preliminary results of a prospective cohort study
Authors: Miscia Maria Enrica , Simeone Pasquale , Bologna Giuseppina , Lanuti Paola , Lisi Gabriele , Pierdomenico Laura , Di Renzo Dacia , Marchisio Marco , Miscia Sebastiano , Lelli Chiesa Pierluigi
Published: August 2023

Circulating Endothelial Cells (CEC) and Circulating Extracellular Vesicles (cEVs) are biological markers of endothelial activity/disfunction and may play a pivotal role in the evolution of IH. Our aims were to detect variations in CEC and cEVs concentration: 1. in IH versus healthy controls; 2. in IH before and after propranolol administration. Twenty-two children (15 cases; 7 controls) from our Department underwent peripheral blood sampling to study CECs, EPCs and EVs via cytofluorimetry. Statistical analyses were performed using XLSTAT ver. 2014.5.03 and GraphPad Prism ver. 8.0. Data were expressed as mean ± standard deviation, median, 5-95th percentile. The number of CEC and HSC was higher among cases than controls, even if not statistically significant. The number of CEC decreased with the evolution of the hemangioma; number of HSC decreased proportionally with the age of the patienst. Number of EVs tended to increase when the CECs decrease and vice-versa in the group of cases but not among controls. Number of CEC and HSC was significantly reduced after oral propranolol administration (p: <0,0001). In conclusion CECs may represent a marker of progression of disease. Propranolol seems to affect the number of CECs and HSCs.
Case series of two different dose regimen Rituximab therapy for severe Pemphigus
Authors: Giuliani Federica , Gualdi Giulio , De Sanctis Paolo , Amerio Paolo
Published: August 2023

Rituximab is a monoclonal antibody approved for treatment of adults with severe and refractory pemphigus vulgaris. Concerns about side effects and high costs of conventional doses have rised the hypothesis that low-dose rituximab regimen may be cost-effective with a better safety profile. Here we report our experience of seven patients with extensive/recalcitrant pemphigus, who either were steroid dependent, had contraindications or refused conventional treatment. Two patients received conventional rituximab (1000 mg 2 weeks apart) while five received ultra low-dose rituximab (200 mg 2 weeks apart). At 3 months, the two patients treated with high Rituximab regimen showed respectively a complete remission off therapy (CROT) and a complete remission on minimal therapy (CRMT), while among the five patients treated with ultra low-doses, three achieved CROT, one achieved CRMT and one a partial remission off therapy (PROT). All patients treated with ultra low-dose rituximab achieved complete depletion of cd19+ and cd19/45+ B lymphocytes after three months and all patients except one male manteined the zeroing after 6 months. No serious side effect was documented with low dose regimen except for a case of diziness. Our data suggest that ultra low-dose rituximab can be effective even in patients with extensive/recalcitrant pemphigus, with a lower probability of side-effects  respect to higher dose regimen and may act as a steroid sparing strategy.
Effects of low dose bisphosphonates treatment on the mandibular bone in rats with and without mini-implants application: an experimental model
Authors: Centofanti Antonio , Runci Anastasi Michele , Favaloro Angelo , De Ponte Francesco Saverio , Catalfamo Luciano , Cutroneo Giuseppina , Vermiglio Giovanna
Published: August 2023

Bisphosphonate-Related Osteonecrosis of the Jaw (BRONJ) is a pathological condition observed in patients underwent oral surgical procedures during bisphosphonates treatment. Although several studies have focused on the BRONJ, the exact pathophysiological pathways remain still unclear. In this study we aimed to observe the effects of the low-dose bisphosphonates administration on mandibular bone of rats with and without mini-implants application. For this study we used 28 male Wistar rats, divided in in two groups: 1) control group, treated with saline solution (n = 14 rats); 2) ZA group, treated with low dose zoledronic acid (n=14 rats). After 6 weeks of treatment, the half of each group underwent mini-implant application. All rats were sacrificed and their mandibles were analyzed by light microscopy and scanning electron microscopy (SEM). Our data have shown a healthy bone tissue of control group both with and without mini-implant application. In the treated group empty osteocyte lacunae have been observed and they slightly increase in rats with mini-implant application. Although that, no bone exposition has been observed. By that, during low dose zoledronic acid treatment we can observe the presence of empty osteocytes lacunae, also called “primary lesion”, that not seem to be sufficient alone to determine osteonecrosis of the jaw spontaneously or even after mini-implant application.
Molecular Detection of Carbapenem's Genes Among (Pseudomonas Areuginosa) Isolates
Authors: Najim Abdullah Qasim , A. Ali Al-Dahhan Hawraa , Rostamzad Arman
Published: August 2023

The antibiotic susceptibility of 125 P. aeruginosa isolated from 215 clinical samples (blood, urine, wound swab samples, sputum, and cerebrospinal fluid) was determined using the disk diffusion method on the Muller-Hinton agar medium. The results showed that the isolates had a high resistance rate to carbenicillin (83.2%) and piperacillin (76%). Resistance to imipenem and meropenem were 7.4% and 14.8%, respectively, while the highest resistance was found against gentamicin (77.9%) and amikacin (75.2%). The modified Hodge test was used to identify carbapenem-resistant isolates, which detects the probability of isolates being able to produce carbapenemases enzyme and out of the isolates, 11 (33.3%) were Hodge positive. The imipenem-meropenem-EDTA disk synergy test showed that only 17 isolates (51.5%) were positive. The carbapenemase genes were detected using PCR technology, and the most prevalent genes were MBL genes, which were carried by 17/33 (51%) of the isolates. The blaIMP gene (578 bp) was the most frequently detected MBL gene, being present in 15 (45.5%) of the carbapenem-resistant isolates. Among the isolates, 11 (33.3%) carried the blaIMP-type gene alone, while 2 (6.06%) carried it with the blaVIM-type gene and another 2 (6.06%) carried it with the blaNDM-type gene. Moreover, 2 (6.06%) isolates carried the blaVIM-type gene. However, results revealed that blaIMP-type genes were the most common MBL gene combination among the isolates. Moreover, 4 (12.1%) isolates carried a blaIMP -type gene.
Evaluation of Silver-Impregnated Hydro-fiber Dressing in the Non-Operative Management of Omphalocele
Authors: Morshed G. M. , Islam Shahnoor , Das Bipul Bhusan , Rashid Mohammad Syfur
Published: August 2023

Background: In the arena of pediatric surgery, omphalocele is one of the most common abdominal wall defects. In the non-operative management of omphalocele, silver-impregnated hydro-fiber dressing is widely used. But in Bangladesh, we do have not enough research-based data regarding the effectiveness and outcomes of this procedure in the non-operative management of omphalocele. Aim of the study: This study aimed to evaluate the effectiveness and outcomes of silver-impregnated hydro-fiber dressing in the non-operative management of omphalocele. Methods: This was a prospective interventional study and was conducted in the Department of Pediatric Surgery, Dhaka Medical College and Hospital (DMCH), Dhaka, Bangladesh from March 2018 to June 2020. In total 10 neonates with omphalocele using silver-impregnated hydro-fiber dressing were enrolled in this study as the study subjects. The random sampling (Lotter) method was applied in the sample selection procedure. Data were collected in a pre-designed data collection sheet. Data were processed, analyzed and disseminated by using the MS Office program. Results: In this study, the male-female ratio of the participants was 1:2.3. The mean ±SD age of the respondents was 1.0 ±0.66 years. In the majority of the neonates (90%), the size of the omphalocele sac was >5 cm and the time to start epithelization was 15.10 ±2.23 days. At the first admission, hospital stay was for 5.10 ±1.19 days in total neonates and the time to start epithelization of the neonates was 15.10 ±2.23 days. In our study, we observed that the time to complete epithelization was 63.60 ±14.60 days. Conclusion: Silver-impregnated hydro-fiber dressing is an effective treatment procedure in the non-operative management of omphalocele.
Qualitative Phytochemistry, Antioxidant potential and Antimicrobial Activity of Methanolic Extracts of Rungia repens from Akola Region (MS), India
Authors: Sirsat Ashwini Prakash , Kokate Pratiksha
Published: August 2023

Rungia repens is a common Acanthaceae member growing mostly in agricultural wastelands. This plant is noted to have febrifuge, antitussive, and vermifuge properties. The qualitative phytochemical study of the leaves and stem of R. repens showed that the plant is rich in phytochemical composition. The chemical analysis showed the presence of alkaloids, phenolics, cardiac glycosides, and steroids in the methanolic extract of this plant. The DPPH and FRAP assay showed that the plant parts have significant antioxidant potential. The disc diffusion of the methanolic extract of this plant reveals its antimicrobial activity. Thus, it is stated that the plant has significant antioxidant and antimicrobial potential.
Feasibility and impacts of Bioenergy Trigeneration systems (BioTrig) in disadvantaged rural areas in India
Authors: You Siming , Mašek Ondřej , Biakhmetov Bauyrzhan , Ascher Simon , Lahiri Sudeshna , Bhargava PreetiChaturvedi , Bhaskar Thallada , Sarangi Supravat , Varjani Sunita
Published: August 2023

This project aims to evaluate the techno-economic and social feasibility, and socio-environmental impacts of bioenergy trigeneration (electricity, clean cooking fuel, and green soil conditioner) systems that tackle the triple crisis of poor electrification, household air pollution, and farmland contamination in rural India. This system is called BioTrig. A project workshop has been held in November in India to discuss and finalise action plans. A questionnaire has been developed to understand the energy, resource, and new technology acceptance of rural households in India. Chemical process modelling, life cycle assessment and cost-benefit analysis has been conducted to evaluate the environmental impact and economic feasibility of BioTrig.
Pemeriksaan Status Gizi sebagai Upaya Deteksi Obesitas dan Obesitas Sentral Melalui Pos Pelayanan Terpadu (Posbindu) di Universitas Respati Yogyakarta
Authors: Kadaryati Sri , Wulandari Sri , Murdhiono Wahyu Rochdiat , Masruroh Masruroh , Nugroho Ariyanto , Rusyani Yelli Yani , Puspitawati Theresia , Rodiyah Rodiyah , Wahyuningsih Melania , Prasetyaningrum Yunita Indah , Khasana Tri Mei , Dewi Devillya Puspita
Published: August 2023

Kejadian obesitas dan obesitas sentral meningkat dalam dua dekade terakhir di Indonesia. Pos Pelayanan Terpadu (Posbindu) di Universitas Respati Yogyakarta (UNRIYO) telah dibentuk pada tahun 2021. Instrumen yang digunakan pada pencatatan monitoring kesehatan berupa Kartu Menuju Sehat Faktor Risiko Penyakit Tidak Menular (KMS FR-PTM) memiliki beberapa keterbatasan untuk digunakan pada pelaksanaan posbindu di UNRIYO. Hasil pemeriksaan status gizi yang dilaksanakan kepada para civitas akademik pada posbindu bulan Oktober 2021 menunjukkan tingginya kejadian status gizi lebih berdasarkan indeks massa tubuh (IMT) dan lingkar perut. Pemantauan status gizi diperlukan untuk mengetahui status kesehatan dari para civitas akademik di lingkungan Universitas Respati Yogyakarta. Kegiatan diawali dengan penyusunan instrumen posbindu, sosialisasi instrumen, apersepsi, kemudian pemeriksaan status gizi pada posbindu bulan November 2022. Penyusunan instrumen KMS Posbindu telah dilaksanakan dengan menyesuaikan aplikasi teknis pemeriksaan pada posbindu di UNRIYO, yaitu penambahan beberapa pengukuran dan parameternya, serta cara pengisian KMS yang disesuaikan dengan waktu pelaksanaan posbindu. Berdasarkan hasil pemeriksaan status gizi, diketahui lebih dari setengah jumlah peserta posbindu mengalami status gizi lebih berdasarkan IMT dan lingkar perut. Pemeriksaan kesehatan di posbindu sebaiknya dapat dilakukan secara rutin agar dapat memantau kondisi kesehatan para civitas akademik.

Kata Kunci: Pemantauan Status Gizi, Civitas Akademik, Posbindu, Penyakit Tidak Menular
Appropriation De La Réforme Licence-Master-Doctorat Par Les Étudiants Et Les Enseignants Des Universités De Goma
Authors: - ZAWADI GASINDIKIRA Jaël
Published: August 2023

Tujuan dari penelitian ini untuk mengetahui bagaimana Penerapan sistem akuntansi keuangan yang di terapkan dan Mengetahui mekanisme pelaporan laporan keuangan di Desa Maesan Kecamatan Mojo Kabupaten Kediri. Jenis Penelitian ini menggunakan kualitatif deskriptif.
Jenis data yang dilakukan pada penelitian ini adalah data primer dan data sekunder. Sumber data penelitian adalah data yang dikumpulkan melalui observasi, wawancara langsung dan dokumentasi berupa laporan keuangan. Metode analisis data yang digunakan adalah deskriptif kualitatif antara lain dengan mereduksi data , fokus pada hal-hal penting yang diperoleh peneliti dari lapangan. Kemudian data disajikan untuk memudahkan melihat gambaran penelitian dan menarik kesimpulan atas analisis yang telah dilakukan.
Hasil penelitian ini menunjukkan bahwa penerapan sistem akuntansi keuangan dan pelaporan laporan keuangan di Desa Maesan sudah berjalan dengan baik, dan sesuai dengan landasan - landasan hukum yang berlaku namun ada cacatan dari peneliti untuk lebih meningkatkan ketelitian dalam membuat laporan sebelum di informasikan ke masyarakat, sehingga tercipta transparasi kepada masyarakat
Geoengineering: An Overview
Authors: - Ema Ridhi Gowri Shankar
Published: August 2023

Geoengineering describes the manipulation of specific processes central to the earth’s climate as a means of offsetting the effects of climate change. Initially thought of as a scientific taboo, the case for this manipulation technique is getting increasingly approved by scientists and organizations due to its growing necessity. This paper will cover what exactly geoengineering is, the cases for and against the technique, the science behind it, and whether it has scope for making a real change in the environment.
Identifying Children in Child Trafficking and Begging in Bihar: A Critical Study of the Rights of the Children
Authors: - Chandan Kumar Sinha
Published: August 2023

The Indian environment is particularly prone to this issue since the country has a significant population of poor children, many of whom do not have parental care. As we know Poverty is one of the primary reasons why children are compelled to beg since their families may perceive it as a way to generate some money. Furthermore, children from marginalized areas are more vulnerable to trafficking, with traffickers preying on their vulnerabilities to entice them into exploitation. One thing is that generally, we predict that child trafficking happens with poor children only, but nowadays any child can be trafficked, whether they are poor or rich. The Indian environment is particularly prone to this issue since the country has a significant population of poor children, many of whom do not have parental care. In behind of that many reasons why children are compelled to beg since their families may perceive it as a way to generate some money. Furthermore, children from marginalized areas are more vulnerable to trafficking, with traffickers preying on their vulnerabilities to entice them into exploitation.
Relationship Between Hypothyroid and High LDL Cholesterol
Authors: - Mrs. Rangoli Saxena , - Prof. Dr. Mrs Archna Gupta
Published: August 2023

This paper shows the study of 100 PCOS cases in Rewa district that underwent several investigations for their metabolic conditions. The study suggests that hypothyroid patients usually have an increase in low-density lipoprotein (LDL) -cholesterol which rises due to several mechanisms. The cases were subjected to measures based on factors like diet, lifestyle, and thyroid medicines recommended by the doctors, which shows a decrease in TSH levels resulting in manageable LDL- cholesterol levels. From the study, it was clear that the TSH level drop fast in the cases where medicines were used as compared to the only diet option but if the cases were prescribed both (medicine and diet) they showed a positive faster rate drop in TSH levels resulting drop the LDL level.
The Influence of Social Media Marketing on Impulsive Buying Behaviour of Consumers in Kerala
Authors: - ATHIRA BHASKARAN , - Dr. SWARUPA R
Published: August 2023

In the present era, social media has become an integral aspect of individuals' lives. Platforms like Facebook, Twitter, Instagram, and LinkedIn boast a significant user base that continues to expand with each passing day. Over the recent years, there has been a rise in curiosity surrounding impulsive purchasing tendencies. This surge in interest has sparked the attention of both organizations and researchers, driving them to delve into the psychological motivations that underlie this behaviour. The primary aim of this research was to examine how social media influences the impulsive buying behaviour of customers in the Kerala. Additionally, the study aimed to analyse the key factors that contribute to impulsive buying behaviour among customers. The research approach adopted was both explanatory and descriptive in nature. Regression Analysis was employed to establish connections between variables such as Hedonic Motivation, Trust, website quality and variety seeking and Impulsive Buying Behaviour. The findings indicated a positive and noteworthy correlation between Social Media and customers' impulsive buying behaviour. This highlights the significance of social media for online retailers and marketers in fostering impulsive buying behaviour among consumers.
A Review on Mouth Dissolving Tablet
Authors: - Tanmay Jit , - Dibyendu Shil , - Saptarshi Mukherjee , - Subhajit Mandal
Published: August 2023

Nowadays, dysphagia is an issue with traditional dosage forms like tablets and capsules, which leads to a high prevalence of non-compliance and renders therapy ineffective. Mouth dissolving tablets, which have good hardness, dose homogeneity, and ease of administration and serve as the preferred option of dosage form for paediatrics, geriatrics, and travelling patients, have been designed to eliminate the issues associated with conventional dosage forms. In order to have enough hardness, integrity, and speed up disintegration without water, the MDTs were invented. rapid dissolution Without the use of water, tablets easily dissolve or disintegrate in saliva. Some tablets are truly fast-dissolving tablets because they are made to dissolve in saliva amazingly quickly—within a few seconds. Others have additives that speed up the process of Tablet disintegration in the oral cavity is more properly referred to as fast-disintegrating tablets because it can take them up to a minute to do so. This tablet shape was created to make it possible to administer an oral solid dose form without drinking any liquids. These tablets easily dissolve or break down in the saliva, usually in under 60 seconds.
Durability of Green Concrete Containing Granite Waste Powder
Authors: - URJA SHARMA , - DEVINDER SHARMA
Published: August 2023

THIS PAPER AIMS TO ASSESS THE DURABILITY OF GREEN CONCRETE UNDER THE SUPERVISION OF DR.DEVINDER SHARMA
Sustainability and Trible Concerns in Baraguru Ramachandrappa's 'Shabari'
Authors: - Umesh S Desai
Published: August 2023

Sustainable development has become noteworthy and stylistic phrase in today’s developmental society and its discourse. However, in spite of its massive popularity it has developed over the ages, the concept still seems even ambiguous as many people continue to understands about its very meaning and history, as well as what it entails and implies for development theory and practice. The purpose of this paper is to contribute to the discourse of the tribal concerns further explaining the paradigm and its implications for human actions and thinking in the quest for sustainable development. For this regard Prof. Baraguru Ramachandrappa’s Novel which is written in Kannada language is one example of its kind.
Exploring the Intersection of Tribal Identity and Indian Politics: A Comprehensive Analysis of Tribal Communities' Participation, Representation, and Influence in the Indian Political Landscape
Authors: - Shivendu Kumar Rai , - Kumari Pallavi
Published: August 2023

The participation, representation, and influence of tribal communities within the Indian political landscape are the main points of this research paper's investigation of the complex relationship between tribal identity and Indian politics. Tribal communities make up a sizeable portion of India's diversified population with their unique cultural, social, and historical roots. This essay tries to give a thorough analysis of how tribal identity influences political engagement, including the difficulties they encounter, the degree of representation they achieve, and the influence of their involvement on policy-making. Furthermore, the research delves into the influence of tribal communities on policy-making, governance, and broader political narratives. It explores instances where tribal interests have converged with or diverged from national political agendas and the resultant impact on policy outcomes. Through an analysis of historical cases, contemporary case studies, and the narratives of tribal leaders, the study assesses the strategies employed by tribal communities to assert their demands and aspirations.