bluuebunny/crossref_metadata_2025 huggingface dataset:
Dynamics and Control of Spacecraft With a Generalized Model of Variable Speed Control Moment Gyroscopes
Authors: Viswanathan Sasi P. , Sanyal Amit K. , Leve Frederick , McClamroch N. Harris
Published: January 2015

The attitude dynamics model for a spacecraft with a variable speed control moment gyroscope (VSCMG) is derived using the principles of variational mechanics. The resulting dynamics model is obtained in the framework of geometric mechanics, relaxing some of the assumptions made in prior literature on control moment gyroscopes (CMGs). These assumptions include symmetry of the rotor and gimbal structure, and no offset between the centers of mass of the gimbal and the rotor. The dynamics equations show the complex nonlinear coupling between the internal degrees-of-freedom associated with the VSCMG and the spacecraft base body's rotational degrees-of-freedom. This dynamics model is then further generalized to include the effects of multiple VSCMGs placed in the spacecraft base body, and sufficient conditions for nonsingular VSCMG configurations are obtained. General ideas on control of the angular momentum of the spacecraft using changes in the momentum variables of a finite number of VSCMGs are provided. A control scheme using a finite number of VSCMGs for attitude stabilization maneuvers in the absence of external torques and when the total angular momentum of the spacecraft is zero is presented. The dynamics model of the spacecraft with a finite number of VSCMGs is then simplified under the assumptions that there is no offset between the centers of mass of the rotor and gimbal, and the rotor is axisymmetric. As an example, the case of three VSCMGs with axisymmetric rotors, placed in a tetrahedron configuration inside the spacecraft, is considered. The control scheme is then numerically implemented using a geometric variational integrator (GVI). Numerical simulation results with zero and nonzero rotor offset between centers of mass of gimbal and rotor are presented.
Cohesive-Shear-Lag Modeling of Interfacial Stress Transfer Between a Monolayer Graphene and a Polymer Substrate
Authors: Guo Guodong , Zhu Yong
Published: January 2015

Interfacial shear stress transfer of a monolayer graphene on top of a polymer substrate subjected to uniaxial tension was investigated by a cohesive zone model integrated with a shear-lag model. Strain distribution in the graphene flake was found to behave in three stages in general, bonded, damaged, and debonded, as a result of the interfacial stress transfer. By fitting the cohesive-shear-lag model to our experimental results, the interface properties were identified including interface stiffness (74 Tpa/m), shear strength (0.50 Mpa), and mode II fracture toughness (0.08 N/m). Parametric studies showed that larger interface stiffness and/or shear strength can lead to better stress transfer efficiency, and high fracture toughness can delay debonding from occurring. 3D finite element simulations were performed to capture the interfacial stress transfer in graphene flakes with realistic geometries. The present study can provide valuable insight and design guidelines for enhancing interfacial shear stress transfer in nanocomposites, stretchable electronics and other applications based on graphene and other 2D nanomaterials.
Clinical Assessment Versus MRI Diagnosis of Meniscus Tears
Authors: Brady Megan P. , Weiss Windee
Published: January 2015

Clinical Scenario:

Common injuries in high-level and recreational athletes, nonathletes, and the elderly are medial and lateral meniscus tears. Diagnosis of meniscus tears is done with clinical exam, magnetic resonance imaging (MRI), and arthroscopy. The gold standard is arthroscopy, but accuracy of a clinical exam versus MRI diagnosis of meniscus tears is in question. A clinician’s ability to detect a meniscus tear is beneficial to the patient from a timing standpoint. The process of obtaining an MRI and results could be lengthy, but if the meniscus tear is accurately diagnosed clinically, the patient could be suspended from athletics or specific job duties to prevent further injury. In addition, rehabilitation could be initiated immediately, resulting in better outcomes for the patient. The ability to diagnose a meniscus tear clinically could initiate the rehabilitation process much sooner than waiting for MRI testing and results. Beginning the rehabilitation phase earlier may lead to faster postoperative rehabilitation and better patient outcomes. Clinical detection of a meniscus tear will facilitate possible suspension, early treatment, and rehabilitation recommendations, but the MRI will provide more specific information about the injury, including type and location of tear. Thus, surgical decisions such as operative versus nonoperative or meniscectomy versus repair would be based on MRI results.

Focused Clinical Question:

Is a clinical exam as accurate as an MRI scan for diagnosing meniscus tears?
Validity and Intrarater Reliability of a 2-Dimensional Motion Analysis Using a Handheld Tablet Compared With Traditional 3-Dimensional Motion Analysis
Authors: Belyea Barbara C. , Lewis Ethan , Gabor Zachary , Jackson Jill , King Deborah L.
Published: January 2015

Context: Lower-extremity landing mechanics have been implicated as a contributing factor in knee pain and injury, yet cost-effective and clinically accessible methods for evaluating movement mechanics are limited. The identification of valid, reliable, and readily accessible technology to assess lower-extremity alignment could be an important tool for clinicians, coaches, and strength and conditioning specialists. Objective: To examine the validity and reliability of using a handheld tablet and movement-analysis application (app) for assessing lower-extremity alignment during a drop vertical-jump task. Design: Concurrent validation. Setting: Laboratory. Participants: 22 healthy college-age subjects (11 women and 11 men, mean age 21 ± 1.4 y, mean height 1.73 ± 0.12 m, mean mass 71 ± 13 kg) with no lower-extremity pathology that prevented safe landing from a drop jump. Intervention: Subjects performed 6 drop vertical jumps that were recorded simultaneously using a 3-dimensional (3D) motion-capture system and a handheld tablet. Main Outcomes Measures: Angles on the tablet were calculated using a motion-analysis app and from the 3D motion-capture system using Visual 3D. Hip and knee angles were measured and compared between both systems. Results: Significant correlations between the tablet and 3D measures for select frontal- and sagittal-plane ranges of motion and angles at maximum knee flexion (MKF) ranged from r = .48 (P = .036) for frontal-plane knee angle at MKF to r = .77 (P < .001) for knee flexion at MKF. Conclusion: Results of this study suggest that a handheld tablet and app may be a reliable method for assessing select lower-extremity joint alignments during drop vertical jumps, but this technology should not be used to measure absolute joint angles. However, sports medicine specialists could use a handheld tablet to reliably record and evaluate lower-extremity movement patterns on the field or in the clinic.
Upper-Extremity Physical-Performance Tests in College Athletes
Authors: Taylor Jeffrey B. , Wright Alexis A. , Smoliga James M. , DePew J. Tyler , Hegedus Eric J.
Published: January 2015

Context:

Physical-performance tests (PPTs) are commonly used in rehabilitation and injury-prevention settings, yet normative values of upper-extremity PPTs have not been established in high-level athletes.

Objective:

To establish normative data values for the Closed Kinetic Chain Upper-Extremity Stability Test (CKCUEST) and Upper-Quarter Y-Balance Test (UQYBT) in college athletes and compare results between sports and to analyze the relationship between the 2 tests.

Design:

Observational.

Setting:

Laboratory/athletic facility.

Participants:

257 (118 male, 139 female) Division I athletes participating in basketball, soccer, baseball, lacrosse, volleyball, track and field, and cross-country.

Intervention:

CKCUEST and UQYBT scores were recorded as part of a comprehensive injury-risk screening battery.

Main Outcome Measure:

Pearson correlations assessed the relationship between all measures of the CKCUEST and UQYBT. A factorial ANOVA and a repeated-measures ANOVA (arm dominance) were used to assess interactions between sex, year in school, and sport for CKCUEST and UQYBT scores.

Results:

Normative values for the CKCUEST and UQYBT were established for 9 men’s and women’s college sports. No significant relationships were found between PPT scores. Men scored significantly higher than women for the CKCUEST (P = .002) and UQYBT (P = .010). Baseball players scored significantly higher than athletes from all other sports for the UQYBT (P < .001) but showed nonsignificant trends of lower scores for the CKCUEST than lower-extremity-dominant athletes such as runners (P = .063) and lacrosse players (P = .058).

Conclusions:

Results suggest that average CKCUEST and UQYBT scores in Division I athletes are distinct from those previously reported in recreationally active populations and that performance differences exist between sexes and sports. In addition, the CKCUEST and UQYBT appear to measure different constructs of performance and may complement each other as part of a screening battery.
Brazil's Soy Moratorium
Authors: Gibbs H. K. , Rausch L. , Munger J. , Schelly I. , Morton D. C. , Noojipady P. , Soares-Filho B. , Barreto P. , Micol L. , Walker N. F.
Published: January 2015

Supply-chain governance is needed to avoid deforestation
Curriculum and the Cold War
The New Math A Political History
Christopher J. Phillips
University of Chicago Press, 2014. 241 pp.
Authors: Kilpatrick Jeremy
Published: January 2015

A closer look at the “new math” movement of the 1960s
Understanding artemisinin resistance
Authors: Sibley Carol Hopkins
Published: January 2015

Genetic studies provide clues to how malaria parasites become drug resistant

[Also see Reports by

Straimer
et al.

and

Mok
et al.

]
Evaluation of a Low-Density Hydrogel Microarray Technique for Mycobacterial Species Identification
Authors: Zimenkov Danila V. , Kulagina Elena V. , Antonova Olga V. , Krasnova Maria A. , Chernyaeva Ekaterina N. , Zhuravlev Vyacheslav Y. , Kuz'min Alexey V. , Popov Sergey A. , Zasedatelev Alexander S. , Gryadunov Dmitry A.
Published: January 2015

In addition to the obligatory pathogenic species of the
Mycobacterium tuberculosis
complex and
Mycobacterium leprae
, the genus
Mycobacterium
also includes conditionally pathogenic species that in rare cases can lead to the development of nontuberculous mycobacterial diseases. Because tuberculosis and mycobacteriosis have similar clinical signs, the accurate identification of the causative agent in a clinical microbiology laboratory is important for diagnostic verification and appropriate treatment. This report describes a low-density hydrogel-based microarray containing oligonucleotide probes based on the species-specific sequences of the
gyrB
gene fragment for mycobacterial species identification. The procedure included the amplification of a 352-nucleotide fragment of the gene and its hybridization on a microarray. The triple-species-specific probe design and the algorithm for hybridization profile recognition based on the calculation of Pearson correlation coefficients, followed by the construction of a profile database, allowed for the reliable and accurate identification of mycobacterial species, including mixed-DNA samples. The assay was used to evaluate 543 clinical isolates from two regions of Russia, demonstrating its ability to detect 35 mycobacterial species, with 99.8% sensitivity and 100% specificity when using
gyrB
, 16S, and internal transcribed spacer (ITS) fragment sequencing as the standard. The testing of clinical samples showed that the sensitivity of the assay was 89% to 95% for smear-positive samples and 36% for smear-negative samples. The large number of identified species, the high level of sensitivity, the ability to detect mycobacteria in clinical samples, and the up-to-date profile database make the assay suitable for use in routine laboratory practice.
Monitoring the Quality of HIV-1 Viral Load Testing through a Proficiency Testing Program Using Dried Tube Specimens in Resource-Limited Settings
Authors: Nguyen Shon , Ramos Artur , Chang Joy , Li Bin , Shanmugam Vedapuri , Boeras Debrah , Nkengasong John N. , Yang Chunfu , Ellenberger Dennis
Published: January 2015

HIV-1 viral load (VL) levels are used for monitoring disease progression and antiretroviral therapy outcomes in HIV-infected patients. To assess the performance of laboratories conducting HIV-1 VL testing in resource-limited settings, the U.S. Centers for Disease Control and Prevention implemented a voluntary, free-of-charge, external quality assurance program using dried tube specimens (DTSs). Between 2010 and 2012, DTS proficiency testing (PT) panels consisting of 5 specimens were distributed at ambient temperature to participants. The results from the participants (
n
≥ 6) using the same assay were grouped, analyzed, and graded as acceptable within a group mean ± 3 standard deviations. Mean proficiency scores were calculated by dividing the combined PT scores by the number of testing cycles using a linear regression model. Between 2010 and 2012, the number of participants enrolled increased from 32 in 16 countries to 114 in 44 countries. A total of 78.2% of the participants reported results using 10 different VL assays. The rates of reporting of acceptable results by the participants were 96.6% for the Abbott assay, 96.3% for the Roche Cobas assay, 94.5% for the Roche Amplicor assay, 93.0% for the Biocentric assay, and 89.3% for the NucliSens assay. The overall mean proficiency scores improved over time (
P
= 0.024). DTSs are a good alternative specimen type to plasma specimens for VL PT programs, as they do not require cold chain transportation and can be used on PCR-based assays. Our data suggest that the CDC HIV-1 VL PT program using DTSs positively impacts the testing performance of the participants, which might translate into better and more accurate VL testing services for patients.
Delineating Community Outbreaks of Salmonella enterica Serovar Typhimurium by Use of Whole-Genome Sequencing: Insights into Genomic Variability within an Outbreak
Authors: Octavia Sophie , Wang Qinning , Tanaka Mark M. , Kaur Sandeep , Sintchenko Vitali , Lan Ruiting
Published: January 2015

Whole-genome next-generation sequencing (NGS) was used to retrospectively examine 57 isolates from five epidemiologically confirmed community outbreaks (numbered 1 to 5) caused by
Salmonella enterica
serovar Typhimurium phage type DT170. Most of the human and environmental isolates confirmed epidemiologically to be involved in the outbreaks were either genomically identical or differed by one or two single nucleotide polymorphisms (SNPs), with the exception of those in outbreak 1. The isolates from outbreak 1 differed by up to 12 SNPs, which suggests that the food source of the outbreak was contaminated with more than one strain while each of the other four outbreaks was caused by a single strain. In addition, NGS analysis ruled in isolates that were initially not considered to be linked with the outbreak, which increased the total outbreak size by 107%. The mutation process was modeled by using known mutation rates to derive a cutoff value for the number of SNP difference to determine whether or not a case was part of an outbreak. For an outbreak with less than 1 month of
ex vivo
/
in vivo
evolution time, the maximum number of SNP differences between isolates is two or four using the lowest or highest mutation rate, respectively. NGS of
S
. Typhimurium significantly increases the resolution of investigations of community outbreaks. It can also inform a more targeted public health response by providing important supplementary evidence that cases of disease are or are not associated with food-borne outbreaks of
S
. Typhimurium.
Local Evolutionary Patterns of Human Respiratory Syncytial Virus Derived from Whole-Genome Sequencing
Authors: Agoti Charles N. , Otieno James R. , Munywoki Patrick K. , Mwihuri Alexander G. , Cane Patricia A. , Nokes D. James , Kellam Paul , Cotten Matthew
Published: January 2015

Human respiratory syncytial virus (RSV) is associated with severe childhood respiratory infections. A clear description of local RSV molecular epidemiology, evolution, and transmission requires detailed sequence data and can inform new strategies for virus control and vaccine development. We have generated 27 complete or nearly complete genomes of RSV from hospitalized children attending a rural coastal district hospital in Kilifi, Kenya, over a 10-year period using a novel full-genome deep-sequencing process. Phylogenetic analysis of the new genomes demonstrated the existence and cocirculation of multiple genotypes in both RSV A and B groups in Kilifi. Comparison of local versus global strains demonstrated that most RSV A variants observed locally in Kilifi were also seen in other parts of the world, while the Kilifi RSV B genomes encoded a high degree of variation that was not observed in other parts of the world. The nucleotide substitution rates for the individual open reading frames (ORFs) were highest in the regions encoding the attachment (G) glycoprotein and the NS2 protein. The analysis of RSV full genomes, compared to subgenomic regions, provided more precise estimates of the RSV sequence changes and revealed important patterns of RSV genomic variation and global movement. The novel sequencing method and the new RSV genomic sequences reported here expand our knowledge base for large-scale RSV epidemiological and transmission studies.

IMPORTANCE
The new RSV genomic sequences and the novel sequencing method reported here provide important data for understanding RSV transmission and vaccine development. Given the complex interplay between RSV A and RSV B infections, the existence of local RSV B evolution is an important factor in vaccine deployment.
Country level economic disparities in child injury mortality
Authors: Khan Uzma Rahim , Sengoelge Mathilde , Zia Nukhba , Razzak Junaid Abdul , Hasselberg Marie , Laflamme Lucie
Published: January 2015

Background

Injuries are a neglected cause of child mortality globally and the burden is unequally distributed in resource poor settings. The aim of this study is to explore the share and distribution of child injury mortality across country economic levels and the correlation between country economic level and injuries.

Methods

All-cause and injury mortality rates per 100 000 were extracted for 187 countries for the 1–4 age group and under 5s from the Global Burden of Disease Study 2010. Countries were grouped into four economic levels. Gross domestic product (GDP) per capita was used to determine correlation with injury mortality.

Results

For all regions and country economic levels, the share of injuries in all-cause mortality was greater when considering the 1–4 age group than under 5s, ranging from 36.6% in Organization for Economic Cooperation and Development countries to 10.6% in Sub-Saharan Africa. Except for Sub-Saharan Africa, there is a graded association between country economic level and 1–4 injury mortality across regions, with all low-income countries having the highest rates. Except for the two regions with the highest overall injury mortality rates, there is a significant negative correlation between GDP and injury mortality in Latin America and the Caribbean, Eastern Europe/Central Asia, Asia East/South-East and Pacific and North Africa/ Middle East.

Conclusions

Child injury mortality is unevenly distributed across regions and country economic level to the detriment of poorer countries. A significant negative correlation exists between GDP and injury in all regions, exception for the most resource poor where the burden of injuries is highest.
Thermodynamics of apparent horizons under conformal and Kerr–Schild maps
Authors: Faraoni Valerio , Vitagliano Vincenzo
Published: January 2015

We derive the transformation properties of the internal energy and Kodama temperature of dynamical (spherically symmetric) black hole solutions generated through spacetime mappings. We use the Sultana-Dyer black hole and the Reissner–Nordström solution to provide prototypical examples testing our transformation formulae.
The role of vitamin D in the control ofLeishmaniainfection
Authors: Ramos-Martínez Espiridión , Gutierrez-Kobeh Laila , Villaseñor-Cardoso Mónica Irais
Published: January 2015

Vitamin D has been described as an essential element for maintaining the homeostasis of mineral content in the body and bone architecture. However, our view of the physiological functions of this micronutrient has radically changed, owing to the vast number of properties, not calcium-related, mediated by its nuclear receptor. This receptor has been found in a variety of cells, including the immune cells, where many of the functions performed by vitamin D are related to inflammation. Although the effect of vitamin D has been widely studied in many diseases caused by viruses or bacteria, very little is known about its role in parasitic diseases, such as leishmaniasis, which is a vector-borne disease caused by different species of the intracellular parasite Leishmania spp. This disease occurs as a spectrum of different clinical syndromes, all of them characterized by a large amount of tissue damage, sometimes leading to necrosis. Owing to the involvement of vitamin D in inflammation and wound healing, its role in leishmaniasis must be relevant, and could be used as an adjuvant for the control of this parasitic disease, opening a possibility for a therapeutic application.
Seasonal diet of the northern river otter (Lontra canadensis): what drives prey selection?
Authors: Day Casey C. , Westover Matthew D. , McMillan Brock R.
Published: January 2015

Diet of the northern river otter (Lontra canadensis (Schreber, 1777)) has been examined throughout much of its range and across many habitat types. Few studies have examined prey selection based on prey abundance estimates, however, and prey selection results have been inconsistent. We determined composition, seasonal variation, and prey selection of otter diet in northern Utah comprising multiple habitat types and prey communities. We evaluated the hypothesis that otters take prey according to availability and in inverse proportion to swimming ability. Fish was the primary class of prey taken by otters (96.5%), followed by crustaceans (16.9%). Among families, otter diet was composed primarily of Salmonidae and Cottidae, the two families that dominated the fish community of the main-channel habitat. Otter diet varied seasonally for nearly all classes (G[24] = 127.8, P < 0.001) and families (G[18] = 132.94, P < 0.001) of prey. In particular, fish occurrence was lower during summer than during other seasons (P ≤ 0.05), whereas crustacean (i.e., crayfish (Astacoidea)) occurrence was higher (G[3] = 71.1, P < 0.001). At the family level, occurrence of Salmonidae was greatest during fall (G[3] = 11.7, P < 0.01). Within one of our habitat types, we found otters to select for prey in proportion to abundance and in inverse proportion to swimming ability, with otters selecting for Catostomidae and Cyprinidae, against Salmonidae, and Cottidae according to its abundance. We conclude that habitat type may be the initial driver of prey selection, while factors such as abundance, agility, and life history of prey may be secondary drivers.
Normal quintic surfaces with Kodaira dimension one
Authors: Umezu Yumiko
Published: January 2015

We study normal quintic surfaces in the three-dimensional projective space whose nonsingular models are surfaces of Kodaira dimension one. It turns out that the genus of the base curve of their elliptic fibration is equal to 0 or 1, and the possible values of other invariants of these surfaces and the singularities on them are obtained. We give several examples to show the existence of such surfaces. Moreover we determine the defining equations of general quintic surfaces whose nonsingular models are irregular elliptic surfaces of Kodaira dimension one.
Hodgkin–Huxley neurons with defective and blocked ion channels
Authors: Pang James Christopher S. , Bantang Johnrob Y.
Published: January 2015

We utilize the original Hodgkin–Huxley (HH) model to consider the effects of defective ion channels to the temporal response of neurons. Statistics of firing rate and inter-spike interval (ISI) reveal that production of action potentials (APs) in neurons is not sensitive to changes in membrane conductance for sodium and potassium ions, as well as to the reversal potential for sodium ions, as long as the relevant parameters do not exceed 13% from their normal levels. We also found that blockage of a critical fraction of either sodium or potassium channels (dependent on constant input current) respectively limits the firing activity or increases spontaneous spiking activity of neurons. Our model may be used to guide experiment designs related to ion channel control drug development.
A SIR EPIDEMIC MODEL STRUCTURED BY IMMUNOLOGICAL VARIABLES
Authors: ANGULO OSCAR , MILNER FABIO , SEGA LAURENTIU
Published: January 2015

Standard mathematical models for analyzing the spread of a disease are usually either epidemiological or immunological. The former are mostly ordinary differential equation (ODE)-based models that use classes like susceptibles, recovered, infectives, latently infected, and others to describe the evolution of an epidemic in a population. Some of them also use structure variables, such as size or age. The latter describe the evolution of the immune system/pathogen in the infected host — evolution that usually results in death, recovery or chronic infection. There is valuable insight to be gained from combining these two types of models, as that may lead to a better understanding of the severity of an epidemic. In this article, we propose a new type of model that combines the two by using variables of immunological nature as structure variables for epidemiological models. We prove the well-posedness of the proposed model under some restrictions and conclude with a look at a practical application of the model.
INFLUENCE OF DIFFERENT LENGTH OF CORE SUTURE PURCHASE AMONG SUTURE ROW ON THE STRENGTH OF 6-STRAND TENDON REPAIRS
Authors: Okubo Hirotaka , Kusano Nozomu , Kinjo Masaki , Kanaya Fuminori
Published: January 2015

In multi-strand suture methods consisting of several suture rows, the different length of core suture purchase between each suture row may affect the strength of repairs. We evaluated the influence of the different length of core suture purchase between each suture row on the strength of 6-strand tendon repairs. Rabbit flexor tendons were repaired by using a triple-looped suture technique in which the suture purchase length in each suture row was modified. Group 1, all lengths are 8-mm. Group 2, all lengths are 10-mm. Group 3, two are 10-mm and one is 8-mm. Group 4, one is 10-mm and two are 8-mm. The repaired tendons were subjected to load-to-failure test. The gap strength was significantly greater in Group 1 and Group 2 than in Group 3 and Group 4. This study demonstrates that maintaining equal core suture purchase lengths of each suture row increases the gap resistance.
IMPACT OF PHRENIC NERVE PARALYSIS ON THE SURGICAL OUTCOME OF INTERCOSTAL NERVE TRANSFER
Authors: Kita Yusuke , Tajiri Yasuhito , Hoshikawa Shinya , Hara Yukinori , Iijima Junichi
Published: January 2015

Brachial plexus injuries (BPI) can be complicated by diaphragmatic paralysis (DP). This study determined the influence of DP on biceps brachii (BB) recovery after intercostal nerve transfer (ICNT) for BPI and investigated the respiratory complications of ICNT. The study included 100 patients, 84 showing no DP in preoperative and early postoperative chest radiographic images (non-DP group) and 16 with DP that persisted for over one year after surgery (DP group). The postoperative reinnervation time did not differ between groups. BB strength one year after surgery was lower in the DP group than non-DP group (p = 0.0007). No differences were observed 2–3 years after surgery. In the DP group, four patients had respiratory symptoms that affected daily activities and their outcomes deteriorated (p = 0.04). Phrenic nerve transfer should not be combined with ICNT in patients with poor respiratory function because of the high incidence of respiratory complications.
PATIENT RELATED FUNCTIONAL OUTCOME AFTER TOTAL WRIST ARTHROPLASTY: A SINGLE CENTER STUDY OF 206 CASES
Authors: Sagerfors Marcus , Gupta Anil , Brus Ole , Rizzo Marco , Pettersson Kurt
Published: January 2015

Objectives: To prospectively evaluate patient related outcome measures after total wrist arthroplasty (TWA) using four different total wrist implants operated at a single referral center in Sweden. Methods: 206 primary TWAs were assessed preoperatively and after one year postoperatively with respect to the following eight outcome measures: Range of motion (flexion/extension, radial/ulnar deviation, pronation/supination), hand grip strength, Canadian Occupational Performance Measure (COPM), performance and satisfaction, Visual Analog Scale (VAS) pain scores at rest and in activity. Results: The Maestro TWA had a significantly greater improvement of radial/ulnar deviation than the Biax and Remotion TWAs. COPM performance and satisfaction improved more for the Maestro and Universal 2 prostheses than the Biax and Remotion. Conclusions: All four TWAs offer reduced VAS-scores and improved COPM-scores with preserved hand grip strength and somewhat improved range of motion. The Maestro TWA performed favorably compared to the Remotion TWA. Implant design may affect patient related outcome.
DELINEATION OF EXTENSOR TENDON OF THE HAND BY MRI: USEFULNESS OF "SOAP-BUBBLE" MIP PROCESSING TECHNIQUE
Authors: Tsujimoto Yumiko , Ryoke Koji , Yamagami Nobuo , Uchio Yuji , Tanaka Shigeko
Published: January 2015

To evaluate the capability of the "Soap-Bubble" maximum intensity projection (MIP) processing technique in visualisation of extensor tendons of the hand, 36 intact subjects and seven patients with surgically confirmed extensor tendon rupture were examined. Three-dimensional T1-weighted turbo spin echo (3DT1TFE) MRI was performed using a sensitivity encoding flex coil, followed by Soap-Bubble MIP processing. For patients with extensor tendon ruptures, MRI findings and intraoperative findings were compared. As results, with only 3DT1TFE sequence, the entire extensor tendons that run along the arch of the hand were not shown on one image, but were visualised with addition of Soap-Bubble MIP. Although delineation of the extensor pollicis longus was poor in 27/43 subjects, it was much improved by the combination of water-suppression technique. MRI findings and intraoperative findings agreed in all patients. Soap-Bubble MIP processing with addition of water-suppression technique is considered useful for visualising the extensor tendons of the hand.
A RETROSPECTIVE REVIEW OF TROUBLED REPLANTATIONS
Authors: Chia Dawn Sinn Yii , Tay Shian Chao
Published: January 2015

Introduction: Replantation surgery is an established treatment for amputated digits, and published literature report a high success rate. However, a proportion of replantations do encounter postoperative problems with vascularity, but the incidence is unknown. Although there are studies that look at the factors affecting the success of replantations and the management of postoperative replantations, there is little literature available on this transitional period. We introduce the term "troubled replantation" to describe the replantation that manifests any form of vascular insufficiency after replantation surgery. Our study focuses on reviewing our centre's experience with the management and outcomes of troubled replantations. Materials and Methods: Data was collected retrospectively from 389 digital replantations performed in our centre over an 11 year period. We included only single level digital replantations. We analysed the perioperative data, and the measures taken postoperatively to promote their survival. Results: There were a total of 137 troubled digits (35.2%). 53 digits responded to non-surgical measures such as dressing change and bedside bleeding procedures. 27 digits required re-exploration surgery, of which 16 survived. The majority of troubled replantations were due to arterial causes, and manifested signs within the first 48 h. 69 troubled digits (51%) survived. The remainder did not respond to any form of treatment including re-explorations and ultimately failed. Conclusion: One third of all replantations are troubled replantations, and half of these eventually fail despite any intervention. As troubled replantations can lead to postoperative failure, it is important to understand this clinical scenario in order to improve immediate postoperative care.
POSTOPERATIVE VOLUMINAL FLAP REDUCTION AFTER FINGERTIP RECONSTRUCTION USING THE REVERSE DIGITAL ARTERY ISLAND FLAP
Authors: Usami Satoshi , Kodaira Satoshi , Homma Tsutomu , Okazaki Mutsumi
Published: January 2015

A total of 16 fingers of 16 patients were subjected to fingertip reconstruction using the reverse digital artery island flap (RDAIF). We evaluated the influences of postoperative flap congestion, initial harvested flap size, patient's age and smoking habit on postoperative final flap size and postoperative range of total active motion (TAM) in affected fingers at a mean interval of 11.4 months. In the results, final flap size and TAM showed a tendency to decrease with increase in the initial harvested flap size and age. Eventually, the final flap size moved towards the size of the fingertip defect. Factors of flap congestion and smoking habit had little influence on the change in flap size and TAM. In conclusion, wide harvested flaps showed significant postoperative reduction in size compared with the small flaps, and extensive skin defect after flap harvest caused a decrease in postoperative TAM. Thus, the size of the harvested RDAIF should be comparable to that of the fingertip defect to prevent postoperative decrease in range of motion in affected fingers, and indication of this flap to the elderly needs to be considered.
Singular convolution operators on Wiener amalgam spaces
Authors: Cheng Meifang
Published: January 2015

The purpose of this paper is to investigate some properties of the Wiener amalgam spaces. As applications, we study the boundedness properties of some singular convolution operators on such spaces. From our results, we will see that, besides modulation spaces, Wiener amalgam spaces are another good substitutions for Lebesgue spaces.
Coding theory on h(x) extension of m sequences for Fibonacci numbers
Authors: Prasad Bandhu
Published: January 2015

In this paper, we introduced h(x) extension of m sequences of Fibonacci numbers polynomials of order m and a new Sn matrix of order m where h(x)(> 0) is a polynomial with real coefficients. Thereby, we discuss various properties of Sn matrix and the Fibonacci coding theory followed from this matrix. We established the relations among the code matrix elements, error deduction and correction for this coding theory. In general, correct ability potential of this method increases and it is independent of h(x). But h(x) being a polynomial, improves the cryptography protection.
Photocatalytic Elimination of Cr(VI) in Aqueous Solution by Using ZSM-5 Zeolite as Catalyst and Urea as Coexisting Organic Contaminants
Authors: Shao Dadong , Wang Xiangxue , Hou Guangshun , Ma Fengliang , Wang Xiangke
Published: January 2015

The photocatalytic reduction of Cr ( VI ) to Cr ( III ) in aqueous solutions without or with urea (a model organic contaminant) using ZSM-5 zeolite as catalyst under UV illumination was studied. The used ZSM-5 zeolite has the characteristics of pure ZSM-5 zeolite crystalline structure, with the point of zero charge (pHPZC) value of pH = 3.7–3.9. The effects of illumination time, mass content of ZSM-5 zeolite, urea concentrations, Cr ( VI ) initial concentrations and ionic strength on the photocatalytic reduction of Cr ( VI ) to Cr ( III ) were investigated. The results indicated that both the increase of urea concentration and the mass content of ZSM-5 zeolite can improve the photocatalytic reduction of Cr ( VI ) to Cr ( III ) under UV illumination. The results are important to understand the photocatalytic reduction of Cr ( VI ) to Cr ( III ) in natural environment with organic contaminant.
Temporal Auditory Processing and Phonological Awareness in Children with Benign Epilepsy with Centrotemporal Spikes
Authors: Amaral M. I. R. , Casali R. L. , Boscariol M. , Lunardi L. L. , Guerreiro M. M. , Colella-Santos M. F.
Published: January 2015

The aim of this research was to analyze temporal auditory processing and phonological awareness in school-age children with benign childhood epilepsy with centrotemporal spikes (BECTS). Patient group (GI) consisted of 13 children diagnosed with BECTS. Control group (GII) consisted of 17 healthy children. After neurological and peripheral audiological assessment, children underwent a behavioral auditory evaluation and phonological awareness assessment. The procedures applied were: Gaps-in-Noise test (GIN), Duration Pattern test, and Phonological Awareness test (PCF). Results were compared between the groups and a correlation analysis was performed between temporal tasks and phonological awareness performance. GII performed significantly better than the children with BECTS (GI) in both GIN and Duration Pattern test (P<0.001). GI performed significantly worse in all of the 4 categories of phonological awareness assessed: syllabic (P=0.001), phonemic (P=0.006), rhyme (P=0.015) and alliteration (P=0.010). Statistical analysis showed a significant positive correlation between the phonological awareness assessment and Duration Pattern test (P<0.001). From the analysis of the results, it was concluded that children with BECTS may have difficulties in temporal resolution, temporal ordering, and phonological awareness skills. A correlation was observed between auditory temporal processing and phonological awareness in the suited sample.
An Easily Overlooked Presentation of Malignant Psoas Abscess: Hip Pain
Authors: Askin Ayhan , Bayram Korhan Baris , Demirdal Umit Secil , Korkmaz Merve Bergin , Gurgan Alev Demirbilek , Inci Mehmet Fatih
Published: January 2015

Psoas abscess is a rare infectious disease with nonspecific clinical presentation that frequently causes a diagnostic difficulty. Its insidious onset and occult characteristics can cause diagnostic delays. It is classified as primary or secondary. Staphylococcus aureus is the most commonly causative pathogen in primary psoas abscess. Secondary psoas abscess usually occurs as a result of underlying diseases. A high index of clinical suspicion, the past and recent history of the patient, and imaging studies can be helpful in diagnosing the disease. The delay of the treatment is related with high morbidity and mortality rates. In this paper, 54-year-old patient with severe hip pain having an abscess in the psoas muscle due to metastatic cervical carcinoma is presented.
Compression of Extreme-Ultraviolet Ultrashort Pulses by Grating Configurations
Authors: Frassetto Fabio , Miotti Paolo , Poletto Luca
Published: January 2015

The design and realization of grating instruments to condition the spectral phase of ultrashort extreme-ultraviolet pulses are discussed. The main application of such configurations is the temporal compression of pulses by compensating the phase chirp and getting close to the Fourier limit. We discuss the two configurations useful for the realization of ultrafast grating compressors, namely, the classical diffraction mount and the off-plane one. The configuration may be applied to free-electron lasers and high-order laser harmonics.
Modeling and Coordinated Control Strategy of Large Scale Grid-Connected Wind/Photovoltaic/Energy Storage Hybrid Energy Conversion System
Authors: Kong Lingguo , Cai Guowei , Xue Sidney , Li Shaohua
Published: January 2015

An AC-linked large scale wind/photovoltaic (PV)/energy storage (ES) hybrid energy conversion system for grid-connected application was proposed in this paper. Wind energy conversion system (WECS) and PV generation system are the primary power sources of the hybrid system. The ES system, including battery and fuel cell (FC), is used as a backup and a power regulation unit to ensure continuous power supply and to take care of the intermittent nature of wind and photovoltaic resources. Static synchronous compensator (STATCOM) is employed to support the AC-linked bus voltage and improve low voltage ride through (LVRT) capability of the proposed system. An overall power coordinated control strategy is designed to manage real-power and reactive-power flows among the different energy sources, the storage unit, and the STATCOM system in the hybrid system. A simulation case study carried out on Western System Coordinating Council (WSCC) 3-machine 9-bus test system for the large scale hybrid energy conversion system has been developed using the DIgSILENT/Power Factory software platform. The hybrid system performance under different scenarios has been verified by simulation studies using practical load demand profiles and real weather data.
Genetic Deletion of Soluble Epoxide Hydrolase Attenuates Inflammation and Fibrosis in Experimental Obstructive Nephropathy
Authors: Chiang Chin-Wei , Lee Hsueh-Te , Tarng Der-Cherng , Kuo Ko-Lin , Cheng Li-Ching , Lee Tzong-Shyuan
Published: January 2015

Soluble epoxide hydrolase (sEH) is abundantly expressed in kidney and plays a potent role in regulating inflammatory response in inflammatory diseases. However, the role of sEH in progression of chronic kidney diseases such as obstructive nephropathy is still elusive. In current study, wild‐type (WT) and sEH deficient (sEH−/−) mice were subjected to the unilateral ureteral obstruction (UUO) surgery and the kidney injury was evaluated by histological examination, western blotting, and ELISA. The protein level of sEH in kidney was increased in UUO‐treated mice group compared to nonobstructed group. Additionally, UUO‐induced hydronephrosis, renal tubular injury, inflammation, and fibrosis were ameliorated in sEH−/− mice with the exception of glomerulosclerosis. Moreover, sEH−/− mice with UUO showed lower levels of inflammation‐related and fibrosis‐related protein such as monocyte chemoattractant protein‐1, macrophage inflammatory protein‐2, interleukin‐1β (IL‐1β), IL‐6, inducible nitric oxide synthase, collagen 1A1, and α‐actin. The levels of superoxide anion radical and hydrogen peroxide as well as NADPH oxidase activity were also decreased in UUO kidneys of sEH−/− mice compared to that observed in WT mice. Collectively, our findings suggest that sEH plays an important role in the pathogenesis of experimental obstructive nephropathy and may be a therapeutic target for the treatment of obstructive nephropathy‐related diseases.
Dependence of Thyroid Sonographic Markers of Malignancy and Its Influence on the Diagnostic Value of Sonographic Findings
Authors: Woliński Kosma , Stangierski Adam , Szczepanek-Parulska Ewelina , Gurgul Edyta , Ruchała Marek
Published: January 2015

Introduction. Thyroid nodules constitute frequent medical condition. Ultrasonographic (US) examination remains the basis in the diagnostics of nodular goiter and selection of the suspected ones requiring fine-needle aspiration biopsy (FNAB). The aim of this study was to evaluate if the features so far considered to be US malignancy markers are dependent or independent variables and to check if these data are clinically relevant.Materials and Methods. Patients with diagnosed thyroid nodular goiter admitted for thyroidectomy, irrespectively of the indications for surgery, were involved. The following parameters were assessed: echogenicity, the presence of calcifications, presence of halo, shape, margins, structure (solid, partially or pure cystic), and elasticity of the nodules (assessed quantitatively).Results. 122 consecutive patients with 393 thyroid nodules were included. There were significant associations between halo absence and irregular borders, micro- and macrocalcifications, taller-than-wide feature and macrocalcifications, irregular margins and macrocalcifications, and also decreased elasticity of nodules and several attributes (partially cystic character, micro- and macrocalcifications).Conclusions. Not only diagnostic value of particular sonographic features but also data about cooccurrence and associations between them are clinically relevant. Although most of these features turned out to be independent, omitting significant association can lead to incorrect assessment of the risk of malignancy.
Serum miR-224 Reflects Stage of Hepatocellular Carcinoma and Predicts Survival
Authors: Zhuang Li-ping , Meng Zhi-qiang
Published: January 2015

Background. In our previous study, we conducted a systematic screening of miRNA to identify potential serum biomarkers for predicting venous metastasis and survival in patients with hepatocellular carcinoma (HCC). miR-224 was one of the differentially expressed miRNAs. This study aimed to confirm whether serum miR-224 level is associated with the presence of venous metastasis and survival.Methods. TaqMan miRNA probe was used to perform qRT-PCR assays to evaluate the expression of serum miR-224 in a cohort of 182 HCC patients.Results. Patients with high miR-224 serum level showed poor survival compared to that with low miR-224 serum level (HR 1.985; 95% CI, 1.08, 3.65,P=0.027). The serum miR-224 levels were significantly higher in the BCLC stage C patients compared with the stage B patients (P=0.005). In further analysis, significant difference of serum miR-224 expression level was observed when patients grouped by the status of PVTT but not the status of extra-liver metastasis (P=0.013andP=0.091). Serum levels of miR-224 showed significant relation with parameters of liver damage and serum AFP.Conclusion. Serum miR-224 might be BCLC stage dependent. It can reflect the status of tumor and liver damage. It was an independent predictor for the survival of HCC patients.
Cardiac Tamponade following Mitral Valve Replacement for Active Infective Endocarditis with Ring Abscess
Authors: Ranjan R. , Lawrence T.
Published: January 2015

Periannular extension and abscess formation are rare but deadly complications of infective endocarditis (IE) with high mortality. Multimodality cardiac imaging, invasive and noninvasive, is needed to accurately define the extent of the disease. Debridement, reconstruction, and valve replacement, often performed in an emergent setting, remain the treatment of choice. Here we present a case of severe IE in a 29-year-old intravenous drug user who after undergoing debridement of the abscess, annular reconstruction, and mitral valve replacement (MVR) presented with recurrence of shortness of breath and pedal edema. Transthoracic echocardiogram (TTE) showed a6.2×5.5 cm cavity, posterior to and communicating with the left ventricle through a 3 cm wide fistulous opening, in proximity of the reconstructed mitral annulus. The patient underwent a redo MVR with patch closure of the fistulous opening, with good clinical outcome. This case highlights the classic TTE findings and the necessity for close follow-up in the perioperative period in patients undergoing surgery for periannular extension of infection. A cardiac magnetic resonance imaging can be considered, preoperatively, in such cases to identify the extent of myocardial involvement and surgical planning.