bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of xanthan gum and xanthan-g-silica derivatives as chemical flooding agents and rock wettability modifiers
Authors: Ashraf Soliman Ahmed , El-hoshoudy Abdelaziz Nasr , Attia Attia Mahmoud
Published: March 2020

Currently, biomolecules flooding in the underground reservoirs acquires sustainable interest owing to their availability and eco-friendly properties. The current study reported chemical displacement by xanthan gum as well as xanthan/SiO2and xanthan grafted with vinylsilane derivatives. Chemical characterization evaluated by traditional spectroscopic methods. Investigation of fluids response to reservoir environment assessed through rheological performance relative to shearing rate, ionic strength, and thermal stability. A sequence of flooding runs generated on 10 sandstone outcrops with different porosity and permeabilities. Core wetness assessed through relative permeability curves at different water saturation. The flooding tests indicate that grafting of the silica derivative overcome the shortage of xanthan solution in flooding operations relative to the reservoir conditions. The ability of the flooding solutions to alter rock wettability explored through relative permeability curves at different water saturation. The results reveal that the synthesized composite was a promised agent for enhancing oil recovery and profile conformance.
Role of GS-5734 (Remdesivir) in inhibiting SARS-CoV and MERS-CoV: The expected role of GS-5734 (Remdesivir) in COVID-19 (2019-nCoV) - VYTR hypothesis.
Authors: Vityala Yethindra
Published: March 2020

Coronaviruses (CoVs) are enveloped RNA viruses related to the family Coronaviridae, the order Nirdovales, and observed in humans and other mammals. In December 2019, many pneumonia cases reported by patients with unknown causes, mainly associated with seafood and wet animal market in Wuhan, China, and where clinically resembled viral pneumonia. At present, there is no existence of antiviral drugs for the treatment of CoV infections. The results of our study are GS-5734 strongly inhibits SARS-CoV and MERS-CoV in HAE cells, GS-5734 inhibits CoVs at early stages in replication by inhibiting viral RNA synthesis, the absence of ExoN-mediated proofreading in viruses sensitive to treatment with GS-5734. Protease inhibitors can show improved outcomes in some coronaviruses, but mostly 99% of protease inhibitors bind to proteins present in the human body, and only 1% attacks on existed viruses. The expected role of GS-5734 (Remdesivir) in the 2019-nCoV - VYTR hypothesis explained. As broad-spectrum drugs are capable of inhibiting CoV infections, GS-5734 is a broad-spectrum drug and may show inhibition on CoV infections and 2019-nCoV. GS-5734 will show desired results regarding antiviral activity against 2019-nCoV as it showed potent antiviral activity in other CoVs. More clinical trials and experiments needed to prove that GS-5734 (Remdesivir) is a potential and effective drug to treat 2019-nCoV.
TIME TO THE END OF PRIMARY CONSOLIDATION (EOP) OF SOFT CLAYEY SOILS: CONCERNING THE EFFECT OF ATTERBERG’S LIMIT AND CYCLIC LOADING HISTORY
Authors: Nhàn Trần Thanh
Published: March 2020

In order to observe the end of primary consolidation (EOP) of cohesive soils with and without subjecting to cyclic loading, reconstituted specimens of clayey soils at various Atterberg’s limits were used for oedometer test at different loading increments and undrained cyclic shear test followed by drainage with various cyclic shear directions and a wide range of shear strain amplitudes. The pore water pressure and settlement of the soils were measured with time and the time to EOP was then determined by different methods. It is shown from observed results that the time to EOP determined by 3-t method agrees well with the time required for full dissipation of the pore water pressure and being considerably larger than those determined by Log Time method. These observations were then further evaluated in connection with effects of the Atterberg’s limit and the cyclic loading history.
Early Algebra: A álgebra que emerge das estratégias de resolução utilizadas por alunos dos anos iniciais
Authors: Bastos Lígia Sousa , Merlini Vera Lúcia
Published: March 2020

Este artigo apresenta uma análise das respostas dadas por alunos dos anos iniciais do Ensino Fundamental no que tange os conceitos algébricos. O objetivo desse trabalho foi analisar as estratégias de resolução dos alunos frente a duas situações que contemplam o contexto das equações, dando enfoque aos conceitos algébricos que emergem dessas resoluções. A metodologia empregada para tal fim foi baseada no método clínico piagetiano em que os alunos eram indagados quanto às suas respostas no momento em que respondiam às questões do instrumento diagnóstico aplicado. A pesquisa revelou que alunos dos anos iniciais do Ensino Fundamental conseguem resolver situações com ênfase nas equações e na relação funcional. No entanto, sentem dificuldades de fazer algumas relações entre elementos presentes nos problemas que envolvem as equações.
TRAFİK GÜVENLİĞİ BAĞLAMINDA DÜRTÜSEL SÜRÜCÜLÜĞÜN SÜRÜCÜ ÖFKE İFADESİ İLE İLİŞKİSİ
Authors: ÖZKAN Özgün , ÖZTÜRK İbrahim , ÖZ Bahar
Published: March 2020

Güvenlik, askerî güvenlik, ekonomik güvenlik gibi farklı boyutlarda ve
bireysel, toplumsal seviye gibi farklı seviyelerde incelenebilen bir kavramdır.
Trafik bağlamında güvenlik de farklı boyut ve seviyelerde kendini gösteren,
günümüzde önemi azımsanan bir konu ve toplum sağlığı ve güvenliği problemidir.
Bu durum, trafik ortamlarında suç sayılan veya suç oluşturma potansiyeline
sahip davranış ve özelliklerin incelenmesinin önemini göstermektedir. Bu
çalışmanın amacı, bu özellikler arasında yer alan dürtüsel sürücülük ve sürücü
öfke ifadesi değişkenleri arasındaki ilişkinin trafik ortamına özgü ölçümler
kullanılarak araştırılmasıdır. Çalışmaya, 18-25 yaş aralığında 237 ehliyet
sahibi üniversite öğrencisi katılmıştır. Katılımcılardan demografik bilgi
formu, Dürtüsel Sürücü Davranışları Ölçeği ve Sürücü Öfke İfadesi Ölçeği’nden
oluşan anketi yanıtlamaları istenmiştir. Dürtüsel sürücülük ve sürücü öfke
ifadesi arasındaki ilişkinin incelenmesi amacıyla cinsiyet ve hayat boyu
gidilen yol miktarı değişkenlerinin istatistiksel etkileri kontrol edilerek
hiyerarşik regresyon analizleri yapılmıştır. Sonuçlar, genç sürücülerde
dürtüsel sürücülük alt boyutlarının sürücü öfke ifadesiyle ilişkili olduğunu
göstermektedir. Özellikle sürücü sıkışıklığı, sürücü öfkesinin saldırgan ifade
boyutlarıyla pozitif ilişki gösterirken, uyum sağlayıcı/yapıcı ifadesi ile
negatif ilişki göstermiştir. Bu çalışma kapsamında literatürde ilk defa sürücü
dürtüselliğinin sürücü öfke ifadesi ile ilişkisi, trafik ortamına özgü
ölçümlerin kullanımı ile incelenmiştir. Elde edilen sonuçlar trafik güvenliği
ile ilişkilendirilerek tartışılmıştır.
DOĞU AKDENİZ’DE DENİZ YETKİ ALANLARI VE ENERJİ KAYNAKLARI ÇERÇEVESİNDE TÜRKİYE’NİN ENERJİ GÜVENLİĞİ
Authors: PEKER Hasan Sencer , ÖZTÜRK OKTAY Kübra , ŞENSOY Yavuz
Published: March 2020

Dünyada artan

enerji ihtiyacı ve bağımlılığı; tarihsel önemini yüzyıllardır koruyan Doğu

Akdeniz’i günümüzde tekrar diplomasinin merkezine çekmeye başlamıştır. Doğu

Akdeniz’de bulunan hidrokarbon rezervleri kıyıdaş devletlerin bu rezervler

üzerinde arama ve yararlanma hakkı iddia etmeleri ve bu iddia edilmiş haklarını

hukuki zemine oturtabilmek için ikili anlaşmalar yapmalarına sebep olmuştur.

Ancak bu rezervlerden yararlanma hakkının hem Kuzey Kıbrıs Türk Cumhuriyeti’nin

varlığını hem de Türkiye ve Kuzey Kıbrıs Türk Cumhuriyeti arasındaki ikili

anlaşmayı göz ardı etmesi sebebiyle bölgede bir takım gerilimler ortaya

çıkmaktadır. Kıbrıs adasının hukuki durumu da göz önünde bulundurulduğunda,

rezervlerden elde edilen ekonomik değerlerin hem ada halkının ortak çıkarına

sunulmaması hem de Türkiye’nin Kuzey Kıbrıs Türk Cumhuriyeti ile anlaşmasından

doğan yetki alanlarının gasp edilmesi açısından önemi bulunmaktadır.

Bu çalışmada,

Doğu Akdeniz’deki tarafların iddia ettiği yetki alanları ve bu alanlardan elde

edilen çıktının paylaşımı uluslararası hukuk nezdinde bir zemine oturtulmaya

çalışılacaktır. Bu sebeple önce Doğu Akdeniz’deki yetki alanlarının

Uluslararası Deniz Hukuku’na uygun biçimde ayrımı yapılacak olup sonrasında

Kıbrıs adasının ve Türkiye’nin Doğu Akdeniz’deki konumuna değinilmiştir. Güney

Kıbrıs Rum Yönetimi’nin adanın tek söz sahibi ve temsilcisi gibi davranmasının

uluslararası hukuka aykırılığından bahsedilecek olup olası çözüm yollarına da

değinilmiştir.
VEKİLLİKTEN ÇATIŞMAYA, ÇATIŞMADAN ORTAKLIĞA: PKK-SURİYE İLİŞKİLERİNİN DEĞİŞEN KARAKTERİSTİĞİ
Authors: SARI Buğra
Published: March 2020

PKK-Suriye ilişkileri 1980 yılında terör örgütü mensuplarının Suriye’de ağırlanmasıyla başlamıştır. 1980’den Ekim 1998’e kadar PKK-Suriye ilişkileri Suriye rejiminin izni ve denetimde sürmüştür. Bu dönemde terör örgütü rejimin Türkiye’ye karşı yürüttüğü vekâlet savaşı dâhilinde faaliyet göstermiştir. Bu doğrultuda Suriye sahası daha kuruluş yıllarından itibaren PKK’nın örgütsel yapılanma, eleman, lojistik ve finans temini ve operasyonel kabiliyeti açısından kilit bir role sahip olmuştur. Ekim 1998’de Türkiye’nin askerî müdahale tehdidinin ardından Suriye rejimi ülkesinde PKK’nın faaliyetlerini yasaklamış ve terör örgütüne karşı harekete geçmiştir. Takiben Suriye rejimi, ülkesinde PYD yapılanması adı altında faaliyetlerine devam eden PKK mensuplarına karşı tutuklamalar gerçekleştirmiştir. Bunun sonucunda terör örgütünün Suriye’deki liderleri Kuzey Irak’a kaçarak Kandil bölgesine sığınmışlardır. Böylece PKK-Suriye ilişkilerinde çatışma dönemi başlamıştır. Bu dönem 2011 Suriye iç savaşına kadar devam etmiştir. 2011 iç savaşıyla birlikte ise PKK-Suriye ilişkilerinde yeni bir aşamaya girilmiştir. Ülkede kontrolü kaybeden rejim PKK’yla bu kez ortaklık ilişkisi kurarak ülkenin kuzey bölgelerini terör örgütüne bırakmıştır. Böylece terör örgütü Suriye’de faaliyet gösteren kolu PYD marifetiyle önemli hâkimiyet alanlarına sahip olmuştur. Böyle bir ortamda PKK Suriye’de 1998 öncesi gibi rejimin çizdiği sınırlar içerisinde ve direktifleriyle hareket eden vekil aktör konumundan, rejimin ortağı konumuna gelmiştir. Buradan hareketle, eldeki çalışma PKK-Suriye rejimi arasındaki ilişkiyi vekillikten çatışmaya, çatışmadan ortaklığa bir süreç olarak tasvir ederek, ikili arasındaki ilişkilerin değişen karakteristiğini irdelemektedir.
SİLAHSIZ SAVAŞ SAHASI: YENİ SAVAŞ ANLAYIŞINDA İSTİHBARATIN YERİ
Authors: ÇITAK Emre
Published: March 2020

Günümüzde pek çok alanda gözlemlenen değişim ve dönüşüm eğilimi savaş anlayışında da kendini göstermektedir. Savaş basit bir şekilde; politikaları, amaçları ve çıkarları doğrultusunda karşı karşıya gelmiş taraflar arasındaki barışçıl olmayan yöntemlere dayanan üstünlük arayışını ifade etmektedir. Geleneksel savaşlar, sınırları belirli bir alanda yüzleşen ve kullanacakları yöntemler çoğunlukla tahmin edilebilir olan belirli düşmanlar arasında gerçekleşmiştir. Yeni dönemin savaşları ise öncekilerden oldukça farklıdır. Her ne kadar içerisine devletler arası sıcak çatışmaları alsa da yeni savaş anlayışı; devletleri büyük çoğunlukla kaynağı, süresi ve etkisi bilinmeyen saldırılardan oluşan savaşları yürütmeye hazırlıklı olmaya yönlendirmektedir. Devletler, sayıları giderek azalan askeri karşılaşmaların yerine siber, iç, vekâlet, asimetrik, ekonomik gibi isimlerle anılan savaşlara uyum sağlamak zorundalardır. Silahların kullanılmadığı, büyük oranda sessizliğin ve görünmezliğin var olduğu yeni savaşlarda ise istihbarat yapıları ve faaliyetleri temel başvuru yöntemi olarak gündeme gelmektedir. Yeni tür savaşların üzerindeki sis perdesinin aralanmasında istihbarat üretimi önemli bir rol oynamaktadır. Çalışmada öncelikle güvenlik, savaş ve istihbarat kavramlarının genel çerçevesi çizilecek, ardından yeni savaş anlayışının genel hatları ve istihbaratın yeni savaş anlayışındaki yeri ele alınacaktır. Yeni tür savaşlarda istihbarat faaliyetlerine yönelik giderek artan ihtiyaç ve bu bağlamda istihbaratın modern savaş sahalarındaki rolü ifade edilecektir. Sonuçta ise genel bir değerlendirme ile beraber ilgili konuda gelecek projeksiyonu yapılacaktır.
Ranking Variable Combinations to Characterize Breast Cancer Subtypes using the IBIF-RF Metric
Authors: Narvaez-Bandera Isis , Torres-Garcia Wandaliz
Published: March 2020

Gene interactions play a fundamental role in the proneness to cancer. However, detect- ing and ranking these interactions is a complex problem due to the high dimensionality of genomic data. Hence, we aim to find patterns composed of multiple features to molecularly characterize breast cancer subtypes from the integration of different omics datasets using a data mining approach. To retrieve biological understanding from these computational results, we developed IBIF-RF (Importance Between Interactive Features using Random Forest), a new metric capable of assessing and holistically ranking the importance of genomic interactions without any prior knowledge of key feature combinations. A set of 247 top-performing features from transcriptomic, proteomic, methylation, and clinical data were used to investigate interactive patterns to classify breast cancer subtypes us- ing over 1150 samples. IBIF-RF metric allowed the extraction of 154312, 190481, and 463917 combinations of variables for TCGA, GSE20685, and GSE21653 datasets. Single genes, MLPH and FOXA1, were the most frequently identified variables across all datasets followed by some two-gene interactions such as CEP55-FOXA1 and FOXC1-THSD4. More- over, IBIF-RF metric allowed the definition of two sets of genes frequently found together (1: FOXA1, MLPH, and SIDT1, and 2: CEP55, ASPM, CENPL, AURKA, ESPL1, TTK, UBE2T, NCAPG, GMPS, NDC80, MYBL2, KIF18B, and EXO1).
Multi-objective Optimisation of Gene Regulatory Networks: Insights from a Boolean Circadian Clock Model
Authors: Akman Ozgur Ekim , Fieldsend Jonathan Edward
Published: March 2020

The gene regulatory networks that comprise circadian clocks modulate biological function across a range of scales, from gene expression to performance and adaptive behaviour. These timekeepers function by generating endogenous rhythms that can be entrained to the external 24-hour day-night cycle, enabling organisms to optimally time biochemical processes relative to dawn and dusk. In recent years, computational models based on differential equations, and more recently on Boolean logic, have become useful tools for dissecting and quantifying the complex regulatory relationships underlying the clock’s oscillatory dynamics. Optimising the parameters of these models to experimental data is, however, non-trivial. The search space is continuous and increases exponentially with system size, prohibiting exhaustive search procedures, which are often emulated instead via grid-searching or random explorations of parameter space. Furthermore, to simplify the search procedure, objective functions representing fits to individual experimental datasets are often aggregated, meaning the information contained within them is not fully utilised.

Here, we examine casting this problem as a multi-objective one, and illustrate how the use of an evolutionary optimisation algorithm — the multi-objective evolution strategy (MOES) — can significantly accelerate the parameter search procedure. As a test case, we consider an exemplar circadian clock model based on Boolean delay equations — dynamic models that are discrete in state but continuous in time. The discrete nature of the model enables us to directly compare the performance of our optimiser to grid searches based on enumeration of the parameter space at a fixed resolution. We find that the MOES generates near-optimal parameterisations in computation times which are several orders of magnitude faster than the grid search. As part of this investigation, we also show that there is a distinct trade-off between the performance of the clock circuit in free-running and entrained photic environments. Importantly, runtime results indicate that the use of multi-objective evolutionary optimisation algorithms will make the investigation of larger and more complex models computationally tractable.
PhGC: A Machine Learning Based Workﬂow for Phenotype-Genotype Co-analysis on Autism
Authors: Shubbar Safa , Fu Chen , Liu Zhi , Wynshaw-Boris Anthony , Guan Qiang
Published: March 2020

Autism spectrum disorder (ASD) is a heterogeneous disorder, diagnostic tools attempt to identify homogeneous subtypes within ASD. Previous studies found many behavioral/- physiological commodities for ASD, but the clear association between commodities and underlying genetic mechanisms remains unknown. In this paper, we want to leverage ma- chine learning to figure out the relationship between genotype and phenotype in ASD. To this purpose, we propose PhGC pipeline to leverage machine learning approach to to identify behavioral phenotypes of ASD based on their corresponding genomics data. We utilize unsupervised clustering algorithms to extract the core members of each clusters and profile the core member subsets to explore the characteristics using genotype data from the same dataset. Our genome annotation results showed that most of the alleles with different frequency among clusters were represented by the core members.
Bayesian Optimisation for Heuristic Configuration in Automated Theorem Proving
Authors: Słowik Agnieszka , Mangla Chaitanya , Jamnik Mateja , Holden Sean , Paulson Lawrence
Published: March 2020

Modern theorem provers such as Vampire utilise premise selection algorithms to control the proof search explosion. Premise selection heuristics often employ an array of continuous and discrete parameters. The quality of recommended premises varies depending on the parameter assignment. In this work, we introduce a principled probabilistic framework for optimisation of a premise selection algorithm. We present results using Sumo Inference Engine (SInE) and the Archive of Formal Proofs (AFP) as a case study. Our approach can be used to optimise heuristics on large theories in minimum number of steps.
Arahan Desain Fasad Koridor Jalan Songoyudan untuk Memperkuat Citra Visual Area Perdagangan Bersejarah di Surabaya
Authors: Rizqiyah Fardilla
Published: March 2020

Songoyudan road corridor is an essential corridor in the area of CBD I which is located in the Old Town of Surabaya. As a commercial corridor, it is filled by rows of shophouses that sells both variety of goods and secondary needs of most citizens in Surabaya. Initially, the existing buildings are the dutch heritage building which were converted into a shophouses. Yet, there are several shop buildings that has been renovated and reconstructed by the owner into a modern style building. As a corridor which is located both in the developing region and high density of activity, the reducing of the colonial heritage buildings is feared to eliminate the visual distinctiveness of the region. This can also be an unfavorable precedent for other buildings owners when renovating or reconstructing their buildings. So that, their vulnerable heritage building will be reconstructed into a new modern style building that can eliminate the historical value in it. This study aims to find an alternate facade design of shophouses in the corridor as a commercial building which can be used as a reference in designing a new one. The used methodology is descriptive qualitative through technical analysis of visual character of colonial buildings. The elements observed included style, color, texture, pattern, and scale of the building. These findings are expected to provide a guidance to the community, including architects and building owners in reconstructing the existing shophouses especially in the road corridors of Songoyudan and generally in the area of the Old Town Hall Kembang Jepun  Surabaya.
Penataan Jalur Hijau di Surabaya Berdasarkan Karakteristik Jalan dan Kemampuan Visual Pengamat Studi Kasus: Jalan Mastrip Surabaya
Authors: Bararatin Kirami , Hayati Arina
Published: March 2020

The main streets and the city entrances of Surabaya support its economic activity as well as become a potential to generate 'first impression' or image of the city for its users. In line with the city government's program, the existence of the green line in the corridor of the main streets should be remarked to develop green space. Consequently,  visual objects on the green line, such as vegetation, need to meet the rules of the visual aesthetic arrangement based on the characteristics of the corridor  and visual capabilities of observers. Jalan Mastrip is  one of the main streets, which is crucial for the city economy and also becomes a city entrance of Surabaya. It has  potential to give a positive ‘first impression‘ for its users. However, the street condition is still beyond  expectation as a city entrance. Therefore, the aim of this study is to formulate the concept of arrangement of green line  in accordance with the characteristics of corridor space and visual capabilities of observers. Descriptive-qualitative method is used supported by the perception of observers / respondents. Then the observations and evaluation results were analyzed to get the arrangement concept of green line of Mastrip corridor, accordance with its characteristics as Surabaya entrance corridor with industry, trade and services concept.
Analisis Permintaan Pupuk Urea Bersubsidi di PT. Pupuk Kaltim Kota Mataram
Authors: Khaeroni Nurmaya
Published: March 2020

Penelitian ini bertujuan untuk : (1) Untuk mengetahui pengaruh harga pupuk urea bersubsidi, luas lahan, pendapatan petani, dan lama pendidikan petani terhadap permintaan pupuk urea bersubsidi di Kota Mataram. (2) Mengetahui elastisitas permintaan pupuk urea bersubsidi bagi petani di Kota Mataram. Penelitian ini menggunakan metode deskriptif. Penentuan lokasi kecamatan dilakukan dengan metode purposive sampling dengan pertimbangan bahwa Kecamatan Sandubaya memiliki jumlah penjualan pupuk urea bersubsidi terbanyak di Kota Mataram pada tahun 2018, dan penentuan lokasi kelurahan dilakukan juga secara purposive sampling dengan pertimbangan bahwa Kelurahan Dasan Cermen memiliki jumlah anggota kelompok tani terbanyak yang menggunakan pupuk urea bersubsidi. Penentuan responden ditentukan secara qouta sampling dengan rumus slovin.Jumlah responden masing-masing kelompok tani ditentukan secara proportional sampling, selanjutnyadua orang pengurus diambil secara purposive sampling dan anggota kelompok diambil secara random sampling.Jenis dan sumber data yang digunakan adalah primer dan sekunder.Hasil penelitian menunjukkan bahwa faktor yang berpengaruh secara nyata pada permintaan pupuk urea bersubsidi di Kota Mataram hanya luas lahan (X2). Elastisitas pendapatan didapatkan sebesar ((-2033833,58) < 1), artinya derajat kepekaan pendapatan konsumen terhadap permintaan pupuk urea bersubsidi memiliki sifat permintaan inelastis.
Házi segítségnyújtás iránti igények időbeliségének mérése
Authors: Meleg Sándor , Ládonyi Zsuzsanna
Published: March 2020

A kutatás témája a házi segítségnyújtás iránti igények időbeli eloszlásának feltérképezése, különös tekintettel az általános szolgáltatási időn (hétköznap, 8–16 óra) túli időszakokban, továbbá, hogy leírja az igényeket befolyásoló tényezőket, és beazonosítsa a munkaidőn túlnyúló időszakokra jellemző tevékenységi igényeket.

A kutatás 103 fős mintán, egy intézmény ellátotti körében, önkéntesen kitöltött, anonim kérdőívekkel került felvételre. A kérdőívek értékelése 5 kutatási kérdés, illetve 7 hipotézis mentén történt. A házi segítségnyújtás iránti keresletben egyértelműen leírható volt az igények időbeli változása napi és heti időrendben, meghatározható volt az egyes tevékenységek iránti igény is. Az adatok alapján szükségesnek mondható az általános szolgáltatási idő keretein kívüli szolgáltatás biztosítása. A gondozási szükségletet feltételezetten befolyásoló háttérváltozók esetében jelentős igénybevételt befolyásoló hatást nem sikerült kimutatni, e téren további kutatásra van szükség.
O rico e o pobre. Estudo da parábola do rico insensível e do pobre Lázaro (Lc 16,19-31)
Authors: Galvão Antônio Mesquita
Published: March 2020

A proposta do autor do artigo é que a parábola contada por Jesus não fique na tradição de uma história contada há dois mil anos atrás, mas penada nossas realidades a ponto de igualmente nos questionar, como acontecia a muitos ouvintes na Galiléia. O ponto de interesse da matéria situa-se no grande abismo, que Abraão diz existir entre o rico e o pobre. Em vida, esse abismo é fruto da indiferença de quem tudo tem, alheio à dor do necessitado. Na morte há como que uma mudança de mão. Quem tudo tinha torna-se carente e pedinte, e quem nada tinha entra no gozo amplo e eterno. Á insensibilidade do rico de todos os tempos é antológica. Á indigência a que o miserável é atirado converte-se em insulto contra a dignidade da pessoa humana de todos os tempos, convertendo-se igualmente num insulto àquele que o criou. A função do biblista é atualizar o fato histórico, fazendo-o reverter em gnomas morais.Abstract: The proposal of the author of the article is that the parable told by Jesus does not remain in the tradition of a story told two thousand years ago, but that it pervades our reality to the point of equally questioning tis, just as it did to many listeners in Galilee. The point of interest of the material is placed within the great separation which Abraham says exists between the rich and the poor. In life, this gap is the fruit of the indiference of those Who have everything and are above the pain of those in need. In death there is as if a change of hands. Those who had everything become needy and begging, and those Who had nothing come into full and eternal satisfaction. The insensibility ofthe richfrom all periods of time is anthological. The misfortune in which the miserable ones are thrown becomes an insult against the dignity of the human beings in all times, converting itself equally into an insult to He Who acated them. Thefunction of the biblical scholar is to bring this historical fact up to date, making it revert into moral statements.
El valor razonable, la eficiencia y la ineficiencia del mercado. El caso de Colombia en la perspectiva de la ley 1314 de 2009
Authors: Álvarez Álvarez Hárold , Álvarez Yepes Juan Sebastián
Published: March 2020

Este artículo se orienta a realizar un análisis del concepto de eficiencia del mercado, sus técnicas de  medición y su relación con el criterio del valor justo de mercado o valor razonable aplicado en el modelo de contabilidad internacional agenciado por el IASB, tanto en los escenarios bursátiles como en los mercados de bienes y servicios; y a reflexionar sobre la pertinencia o inconveniencia de la adopción de tal modelo contable como base regulatoria para Colombia.
Una mirada del pasado hacia el futuro de evolución del pensamiento contable
Authors: Castillo Nossa Dilia , Dávila Giraldo Gloria Cecilia
Published: March 2020

En el presente documento se presenta una reflexión que abarca desde el origen del pensamiento contable, su evolución y concepción como ciencia, reflejada en la situación actual con los espejos de los grandes aportes a la contabilidad por estudiosos que a través del tiempo han dejado huella imborrable en la construcción del saber contable. Así mismo, se denota la clasificación en periodos de avance de la contabilidad, dejando una clara evidencia en la travesía de la misma, pasando de ser un arte, luego técnica y perfeccionándose cada vez más en disciplina científica, a partir de la búsqueda de la verdad. Adicionalmente, se encuentra una mirada en la actualidad, dejando plasmada una preocupación sobre la realidad contable colombiana.
Los fundamentos de la construcción de realidad social de John Searle: una interpretación desde la perspectiva contable
Authors: Durán Caicedo Luz Estela , Parra González Beatriz
Published: March 2020

El trabajo, presenta como objetivo, la aplicación de los fundamentos teóricos argumentados por Searle (1997), en el campo concreto de la contabilidad. Me-todológicamente, el estudio se sustentó en un diseño de investigación basado en dos fases interrelacionadas: la primera, orientada hacia la interpretación de los principales conceptos argumentados por el autor; la segunda, basada en la aplicación de estas construcciones en el campo contable. Para el desarrollo del proceso investigativo se utilizó el enfoque hermenéutico, en vista de su pertinencia para la interpretación del discurso escrito. Los resultados de la investigación se resumen en: a) La contabilidad como actividad profesional de registro e información constituye un hecho institucional; b) Las funciones agentivas y no agentivas se reproducen en el campo contable en el contexto de cada situación a informar; c) Las reglas constitutivas en contabilidad se precisan en las NIIF (criterio de reconocimiento); d) La legitimidad de la contabilidad es producto de su aceptación universal y de la legalidad.
Penguatan Kedudukan Peraturan Desa Dalam Sistem Perundang-Undangan Indonesia
Authors: Wardana Dodi Jaya
Published: March 2020

In Law Number 10 of 2004, Village Regulations are placed as one of the types of Legislation in Indonesia. However, with the birth of Law Number 12 of 2011 concerning the Establishment of Legislation as a substitute for Law Number 10 of 2004 the position of Village Regulations became unclear, even unregulated and not included in the hierarchical system of Legislation in Indonesian. Village Head Regulations, which are the implementing rules of Village Regulations, and are positioned under Village Regulations, are more regulated and incorporated into the Indonesian Legislation System. Furthermore, in Law Number 12 of 2011, regulations regarding hierarchy or position / position of Village Regulations are not regulated. If carefully explored in Law Number 12 of 2011, there is no position in the Village Regulations as a type and explicitly in the hierarchy of Legislation. Therefore, this research is expected to clarify and reinforce the position or position of village regulations in Indonesian legislation. So that Village Regulations can be one of the rules of the Indonesian legislation.
Сравнительный анализ и пробиотический потенциал новых штаммов рода Lactobacillus из эволюционно закреплённых микробных ассоциаций желудочно-кишечного тракта дикой птицы
Authors: Радченко В. , Ильницкая Е. , Шуваева Т. , Александрова М. , Лунева А. , Лысенко Ю. , Басова Н. , Некрасов А. , Кощаев А.
Published: March 2020

Современными молекулярно-биологическими и микробиологическими методами анализа изучена возможность использования в товарном производстве бактериальных штаммов рода Lactobacillus, полученных из содержимого слепых отростков ЖКТ дикого перепела. Штаммы выделены на селективных плотных средах, типированы до вида при определении последовательности гена 16S РНК. Четыре штамма рода Lactobacillus идентифицированы как принадлежащие к видам L. parabuchneri, L. brevis, L. buchneri и L. kunkeei. Проведёны их морфологический анализ и определены культуральные свойства; молекулярное типирование методами ERIC-ПЦР и (GTG)5-ПЦР; экспресс-анализ на наличие в тотальной ДНК 4 отобранных штаммов лактобацилл генов, кодирующих пептиды, подобные педиоцину, низину и энтероцину. В отношении штаммов L. brevis (В-13079) и L. buchneri (В-13078) проведён комплекс экспериментов, подтверждающий возможность использования их в составе пробиотических препаратов. На основе комплекса исследований предложен состав пробиотической добавки «Олигобакт-ДТ», которую можно применять в рационах сельскохозяйственной птицы.
Экспериментальное токсикологическое исследование таблеток для рассасывания с растительным экстрактом
Authors: Бортникова В. , Мизина П. , Крепкова Л. , Бабенко А. , Кузина О. , Боровкова М. , Гуленков А. , Карабаева О.
Published: March 2020

Представлены результаты экспериментальных токсикологических исследований таблеток для рассасывания, содержащих комбинированный растительный экстракт цветков ромашки, календулы и травы тысячелистника, предназначенных для терапии инфекционно-воспалительных заболеваний полости рта и глотки. Показано, что в условиях субхронического эксперимента введение таблеток в ротовую полость кроликам в течение 30 дней в дозах 5 и 10 мг/кг не влияло на основные интегральные и биохимические параметры, характеризующие функциональное состояние печени, почек, сердечно-сосудистой системы экспериментальных животных. Патогистологические исследования подтвердили отсутствие повреждающего действия таблеток на внутренние органы и раздражающего действия на слизистую ротовой полости и желудочно-кишечного тракта кроликов.
Применение фотогенерированного йода для количественного определения рибофлавина в инъекционной форме
Authors: Турусова Е. , Лыщиков А. , Насакин О.
Published: March 2020

Разработана фотохимическая методика определения рибофлавина в инъекционной форме («Рибофлавин-мононуклеотид»), основанная на титровании БАВ раствором фотогенерированного йода, полученного в результате облучения вспомогательного раствора, содержащего сенсибилизатор (эозинат натрия), иодид калия и ацетатный буферный раствор (рН 5,6). Установлено, что стабилизаторы, входящие в лекарственную форму, не мешают определению при содержании 40 и 60 мг для трилона Б и хлоробутанол гидрата соответственно. Найденное в лекарственной форме содержание рибофлавина соответствует заявленному в нормативных документах. Разработанная методика валидна по показателям: линейность, аналитическая область, прецизионность, воспроизводимость (сходимость). Рассчитанный предел обнаружения рибофлавина в инъекционной форме составил 15,3 и 15,5 мкг по изменению силы тока и времени генерации соответственно. Разработанная фотохимическая методика определения рибофлавина характеризуется простотой исполнения, доступностью аппаратурного оформления, следовательно, может быть рекомендована для количественного определения БАВ в любой контрольно-аналитической лаборатории.
MONUMENTS OF NATURE AND HISTORICAL AND CULTURAL OBJECTS OF THE DNISTROVSKYI RLP: THE STATE OF PROTECTION AND THE PROSPECTS OF TOURIST USE
Authors: Zahriichuk Volodymyr
Published: March 2020

The existing nature conservation objects that are part of the Dnistrovskyi Regional Landscape Park are characterized and mapped. There are more than sixty different types of WFD objects in and around the park. All objects are tabulated. Also, geological, geomorphological, hydrological objects have been identified that have scientific, recreational and educational value, which gives grounds for granting them conservation status. This is a large number of rocks of different ages (Silurian, Devonian, Jurassic, Cretaceous), which makes it possible to study the history and condition sof the territory. The location is mapped. Also on the map as places of interest are the places of manifestation of modern geomorphological processes. Fluvial, karst, gravity, erosion and other processes are most evidentin the park.
The dynamics of karst processes haveled to the formation of numerous caves and cave formations, which are valuable from the scientific and recreational plan.
A mong the hydrological and hydro-geological features are waterfalls, marshe sand ground water exits to the surface in the form of springs.
Historical and cultural sites occurring with in and around the park are characterized and mapped. The seare objects of Paleolithic heritage (the oldestin Bukivna, Horodnytsia), Kievan Rus' period, ruins of ancient castles (Rakovetsky and Chekrnelitsky) and fotresses, lordlye states, ancient churches, of which there are more than thirty, existing and in active in the region. The most ancient are the village of Michalce), monuments of liberation competitions (hiding places) and places of great historical battles.
It maps and describes the existing route sand objects of the tourist infrastructure of the Dnistrovskyi RLP. The park and surrounding areas haves ignificant natural and recreational potential. The presence of a large number of diverse natural sites make sit possible to create attractions for tourism development in the region. The presence of historical and cultural heritage en hances the use of the territory.
New routes and proposals for improvement of the tourist infrastructure of the territory were developed: creation of an eco-educational visit center, placement of agroosel complexes, arrangement of places for stops during the Dniester alloys, creation of a network of tourist points at the places of passage of route sand places of rest of residents, development and in stallation of new information standsne are xisting tourist natural and historical sites in the study area.
Key words: Dnistrovskyi RLR, Nature Reserve objects, historical and cultural sites, nature monuments, recreational resources, tourism.
Birth of a “respectable” discipline : from Kant to new epistemological imperialism. On the early history of computer science.
Authors: Akmut Camille
Published: March 2020

How does one establish a science as a respectable discipline? Thefirst decades of computer science; and, from Kant’s conceptions of philosophy asqueen discipline to a new kind of scientific imperialism : science of everything.
Technology for monitoring everyday prosthesis use: a systematic review
Authors: Chadwell Alix , Diment Laura , Amigo Encarna Micó , Morgado Ramirez Dafne Zuleima , Dickinson Alexander , Granat Malcolm Howard , Kenney Laurence , Kheng Sisary , Sobuh Mohammad , Ssekitoleko Robert , Worsley Peter
Published: March 2020

BackgroundUnderstanding how prostheses are used in everyday life is central to the design, provision and evaluation of prosthetic devices and associated services. This paper reviews the scientific literature on methodologies and technologies that have been used to assess the daily use of both upper- and lower-limb prostheses. It discusses the types of studies that have been undertaken, the technologies used to monitor physical activity, the benefits of monitoring daily living and the barriers to long-term monitoring.MethodsA systematic literature search was conducted in PubMed, Web of Science, Scopus, CINAHL and EMBASE of studies that monitored the activity of prosthesis-users during daily-living.Results60 lower-limb studies and 9 upper-limb studies were identified for inclusion in the review. The first studies in the lower-limb field date from the 1990s and the number has increased steadily since the early 2000s. In contrast, the studies in the upper-limb field have only begun to emerge over the past few years. The early lower-limb studies focused on the development or validation of actimeters, algorithms and/or scores for activity classification. However, most of the recent lower-limb studies used activity monitoring to compare prosthetic components. The lower-limb studies mainly used step-counts as their only measure of activity, focusing on the amount of activity, not the type and quality of movements. In comparison, the small number of upper-limb studies were fairly evenly spread between development of algorithms, comparison of everyday activity to clinical scores, and comparison of different prosthesis user populations. Most upper-limb papers reported the degree of symmetry in activity levels between the arm with the prosthesis and the intact arm.ConclusionsActivity monitoring technology used in conjunction with clinical scores and user feedback, offers significant insights into how prostheses are used and whether they meet the user’s requirements. However, the cost, limited battery-life and lack of availability in many countries mean that using sensors to understand the daily use of prostheses and the types of activity being performed has not yet become a feasible standard clinical practice. This review provides recommendations for the research and clinical communities to advance this area for the benefit of prosthesis users.
Predicting Individual Preferences in Mindfulness Techniques Using Personality Traits
Authors: Tang Rongxiang , Braver Todd Samuel
Published: March 2020

The growing popularity of mindfulness-based interventions has prompted exciting scientific research regarding their beneficial effects on well-being and health. Most mindfulness programs are provided as multi-faceted packages encompassing a set of different mindfulness techniques, each with distinct focus and mechanisms. However, this approach overlooks potential individual differences which may arise in response to practicing various mindfulness techniques. The present study investigated preferences for four prototypical mindfulness techniques (focused attention, open monitoring, loving-kindness, and body scan) and identified factors that may contribute to individual differences in these preferences. Participants without prior mindfulness experiences were exposed to each technique through audio-guided instructions and were asked to rank their preferences at the end of all practices. Results indicated that preferences for loving-kindness were predicted by empathy, and that females tended to prefer loving-kindness more than males. Conversely, preferences for open monitoring were predicted by nonreactivity and nonjudgment of present moment experiences. Additionally, higher state mindfulness was detected for individuals’ preferred technique relative to other alternatives. These findings suggest that individuals tend to prefer techniques compatible with their personalities, as the predictor variables encompass trait capacities specifically relevant to practicing these techniques. Together, our results suggest the possibility that assessing individual difference and then tailoring mindfulness-based interventions to individual needs could be a useful way to improve intervention effectiveness and subsequent outcomes.
Beginning with biology: “Aspects of cognition” exist in the service of the brain’s overall function as a resource-regulator
Authors: Theriault Jordan E. , Coleman Matthew B , Feldman Mallory , Fridman Joseph David , Sennesh Eli , Quigley Karen S. , Barrett Lisa Feldman
Published: March 2020

Lieder and Griffiths rightly urge that computational cognitive models be constrained by resource usage, but they should go further. The brain’s primary function is to regulate resource usage. As a consequence, resource usage should not simply select among algorithmic models of “aspects of cognition.” Rather, “aspects of cognition” should be understood as existing in the service of resource management.
Suicide Risk and Protective Factors: A Network Approach
Authors: Holman Mikayla Sarah , Williams Matt N
Published: March 2020

Objective: Suicide is a complex phenomenon, with numerous factors contributing to an individual’s risk of suicide. The aim of the present study was to explore how risk and protective factors for suicide interact with one another in a network sense, and to determine which factors were most central to a network of these factors. Method: Using an online survey, cross-sectional data was collected from a sample of 515 individuals who lived in New Zealand, Australia, the United Kingdom, and the United States of America. Participants were recruited through either social media or Prolific Academic. A network of 18 risk and protective factors for suicide was estimated using network analysis. Analyses were preregistered on the Open Science Framework.Results: Factors that had the highest strength centrality were feeling depressed, feeling hopeless, perceived burdensomeness, self-esteem, and social support. Factors that were directly associated with suicidal ideation included feeling depressed, perceived burdensomeness, feeling hopeless, self-esteem, resilience, access to mental health services and a positive attitude towards these services.Conclusion: This research demonstrates the importance of examining protective factors as well as risk factors when estimating an individual’s suicide risk. The results suggest that interventions targeting depression may be particularly beneficial in reducing suicide risk, but further longitudinal research is required.
Effects of Socio-Structural Variables in the Theory of Planned Behavior: A Mediation Model in Multiple Samples and Behaviors
Authors: Hagger Martin S , Hamilton Kyra
Published: March 2020

Objective. Observed variation in health behavior may be attributable to socio-structural variables that represent inequality. We tested the hypothesis that variability related to socio-structural variables may be linked to variation in social cognition determinants of health behavior. A proposed model in which effects of socio-structural variables (age, education level, gender, income) on health behavior participation was mediated by social cognition constructs was tested. Design. Model effects were tested in correlational datasets (k=13) in different health behaviors, populations, and contexts. Samples included self-report measures of age, highest attained education level, gender, and net household income, and constructs from the theory of planned behavior (attitude, subjective norms, perceived behavioral control, intention). Ten samples provided follow-up self-reports of health behavior. Results. Path analyses supported sample-specific indirect effects of gender and age on health behavior with comparatively few income and education level effects. Meta-analytic structural equation modeling indicated consistent indirect and total effects of gender on intentions and health behavior through social cognition constructs, and a total effect of education level on behavior. Conclusion. Results provide support for the proposed mechanism by which socio-structural variables relate to health behavior. Replication in large representative samples and meta-analytic synthesis across multiple health behavior studies is warranted.
Leveraging big data to understand the interaction of task and language during monologic spoken discourse in speakers with and without aphasia
Authors: Stark Brielle C , Fukuyama Julia
Published: March 2020

Monologic spoken discourse allows us to evaluate every day speech while retaining some experimental constraint. It also has clinical relevance, providing cognitive-linguistic information not measured on typical standardized tests. Here, we leverage big behavioral data (AphasiaBank) to understand how discourse genres (narrative, procedural, expositional), and unique tasks within those genres, influence microstructural elements of discourse (specifically, linguistic forms including part of speech, lexical type [open, closed] and morphological tense). We compare task x microstructure interaction across speakers with and without aphasia and evaluate the influence of aphasia type and severity on this interaction. Using multivariate statistical methods, we find that, for both speaker groups, discourse microstructure is most similar for tasks within the same discourse genre and that microstructure is largely dissociable across discourse genres. The aphasia group had more speaker variance per task, which was partially explained by aphasia type and severity. Our results provide necessary information for usage and interpretation of monologic discourse in research and clinical contexts.