bluuebunny/crossref_metadata_2025 huggingface dataset:
Bell’s Palsy Development in Patients Using Quetiapine Adjunct to Sertraline: A Case Study
Authors: Shalbafan Mohammadreza , Malekpour Farzaneh , Asadi Pegah
Published: August 2020

Introduction: Bell`s palsy is a neurological condition manifests with acute unilateral neuropathy of 7th cranial nerve. The cause is not clear. However, some infections, immune system responses and ischemic causes are suggested as etiologies. We report 2 cases with Bell`s palsy while using quetiapine plus sertraline, in the absence of concurrent prescriptions which have been reported Bell’s palsy as an adverse effect.
Cases Presentation: First patient was an Iranian 54 years old male with Major Depressive Disorder who has been treated by sertraline 100mg per day for 1 year. His main manifestations was depressed mood, fatigue, insomnia, irritability, suicidal ideas and social isolation. He presented the classical manifestations of peripheral Bell`s palsy only 3 days after initiation of quetiapine 50mg per night. Brain imaging such as Magnetic Resonance Imaging (MRI) and Diffusion Weighted Imaging (DWI) was performed. Also other investigations for infective and immune causes were done. All of them showed normal results. The second case was an Iranian 20 year old female diagnosed as Major Depressive and Body dysmorphic disorder patient. She was being treated by sertraline 100 mg/daily plus quetiapine 25md per night for 15 months. She also presented peripheral type of Bell`s palsy while using this combination therapy. Neurological investigations also performed and all results were normal. She recovered after reduction of quetiapine dosage to 12.5 mg per night and prescription of acyclovir and dexamethasone by our neurologist colleague.
Discussion: Based on our search there is no reported correlation between psychiatric medications and Bell`s palsy. First explanation about our cases is an accidental correlation but also the short time correlation between initiation of treatment and presenting Bell’s palsy in first case and recovery of second one after reduction of quetiapine dosage are supporting the idea that the combination of sertraline and quetiapine may causes Bell’s palsy. Some articles have mentioned that antipsychotic drugs may have a weak antibiotic agent role and specially may demonstrate an inhibitory effect on neurotropic viruses, such as herpes simplex. Sertraline may also acts as an antibacterial agent. Reduction of protecting human microbiota may explain our observations.
Conclusion: Combination of sertraline and quetiapine may cause Bell`s palsy and clinicians should consider neurological adverse effects of this common combination
Analysis of Hand Tremor in Parkinson’s Disease: Frequency Domain Approach
Authors: Samadi Elham , Ahmadi Hessam , Nowshiravan Rahatabad Fereidoon
Published: August 2020

Purpose: Parkinson's Disease (PD) is a neuro-degenerative interminable issue causing dynamic loss of dopamine-creating synapses, which is one of the most far reaching ailments after Alzheimer's infection. In this paper, a system for the classification of Parkinson’s disease tremor using noninvasive measurement and frequency domain features is represented.
Materials and Methods: Tremor time-series of Parkinson's disease patients were recorded via a smartphone’s accelerometer sensor. Short-Time Fourier Transform (STFT) was applied to transform the time-domain signal into the frequency domain with high time-frequency resolution. Several frequency features, including mean, max of power spectral density and side frequency have been extracted and by using the FDR algorithm combinations of features carried enough information to reliably assess the severity of tremor in Parkinson patients were determined.
Results: Four different classifiers were implemented to estimate the severity of tremors based on the Unified Parkinson's Disease Rating Scale (UPDRS) in Parkinson's disease patients.
Conclusion: Classifiers’ estimation was compared to clinical scores derived via neurologist UPDRS annotation on Parkinson's disease patients’ tremor. The best accuracy achieved was 95.91±1.51.
Assessment of CT Imaging Protocols Impacts on Calculation of Point Dose in Water Phantom Using Radiotherapy Treatment Planning System
Authors: Fallah Mohammadi Gholamreza , Mihandoost Ehsan
Published: August 2020

Purpose: Point dose calculation in the Treatment Planning System (TPS) is performed using Computed Tomography (CT) images because CT images data have the tissue electron density information. The effect of CT imaging protocols on the calculation of point doses in TPS is one of the most important subjects that was evaluated in this study.
Materials and Methods: CT scan imaging was performed from cylindrical water phantom using three scanner systems and different imaging technical parameters. The CT images data were irradiated in TPS to delivering a 200 cGy radiation dose to the center of the phantom with 6 and 15MV X-Ray photon energy with multiple radiation fields and Monitor Unit (MU) were separately calculated. In the TPS, a virtual water phantom with the same characteristic as CT image phantom was simulated and irradiated with similar conditions. The difference in MU values obtained from two irradiation methods in TPS was compared with Wilcoxon nonparametric test.  
Results: Variations of mA, kV, Pitch, slice thickness, and kernel as CT imaging parameters have not significantly affected radiotherapy point dose calculation (<2%). CT imaging protocols as a thin slice, 80 kV, and sharp kernel have the greatest difference between CT image-based calculation and designed phantom calculation in TPS where wedge field and 6 MV photon energy were used.
Conclusion: The use of CT images obtained with multiple protocols can be used without having a significant effect on the dose calculations of the treatment planning system.
An Application-Based Review of Recent Advances of Data Mining in Healthcare
Authors: Shirazi Saeed , Baziyad Hamed , Karimi Hamed
Published: August 2020

Background: Data mining as an integral part of the knowledge discovery in database (KDD) has gained significant attention over the past few years. By and large, data mining is the process of finding interesting structures in a considerably voluminous amount of data. Owing to its methods and algorithms supporting variable types of data, the data mining approach has been applied in many scientific areas, including the healthcare industry. Regarding this matter, in this paper, we elaborate on the latest papers, including data miningtechniques and algorithms in the healthcare field of research.
Results: We present a data mining review based on the newest researches. Afterward, we categorize data mining papers in healthcare based on supervised and unsupervised learning paradigms as well as classifying them in terms of their applications in the healthcare domain.
Conclusions: In every healthcare application, we propose some summary points of the papers. At last, we delve into the absence and hence, the necessity of existing some novel methods in healthcare domains in this researches.
Combining Multiple Imputation and Inverse-Probability Weighting for Analyzing Response with Missing in the Presence of Covariates
Authors: Osmani Freshteh , Hajizadeh Ebrahim
Published: August 2020

Introduction: Missing values are frequently seen in data sets of research studiesespecially in medical studies.Therefore, it is essential that the data, especially in medical research should evaluate in terms of the structure of missingness.This study aims to provide new statistical methods for analyzing such data.
Methods:Multiple imputation (MI) and inverse-probability weighting (IPW)aretwo common methods whichused to deal with missing data. MI method is more effectiveand complexthan IPW.MI requires a model for the joint distribution of the missing data given the observed data.While IPW need only a model for the probability that a subject has fulldata .Inefficacy in each of these models may causeto serious bias if missingness in dataset is large .Anothermethod that combines these approaches to give a doubly robust estimator.In addition, using of these methodswill demonstrate in the clinical trial data related to postpartum bleeding.
Results:In this article, we examine the performance of IPW/MI relative to MI and IPW alone in terms of bias and efficiency.According to the results of simulation can be said that that IPW/MI have advantages over alternatives.Also results of real data showed that,results of MI/MI doesnot differ with the results ofIPW/MIsignificantly.
Conclusion:Problem of missing data are in many studies that causes bias and decreasing efficacy inmodel.In this study, after comparing the results of these techniques,it was concludedthat IPW/MI method has better performance than other methods.
Investigating the Challenges of Big Data Analytics from the Viewpoints of Students in Mashhad in 2019
Authors: Nazari Elham , Afkanpour Marziyeh , Tabesh Hamed
Published: August 2020

Introduction: Nowadays Big Data Analytics has attracted students for research due to its very high capabilities, but there are also obstacles to analyses that need to be addressed. Therefore, the purpose of this study is to investigate the viewpoints of students of different disciplines at Mashhad universities on the challenges of this analysis.
Method: This study is a cross-sectional study conducted on students of different universities and fields such as computer engineering, pharmacy, industry and biology in Mashhad, Iran. A questionnaire based on literature review in Pubmed, Google scholar, and science direct databases was designed by 10 experts from different disciplines using Delphi method. 185 students participated in the study. Students' viewpoints on the challenges were also collected. Descriptive and analytical results were reported using SPSS 21 and Maxqda software.
Results: The age range of most students was 25 - 34 years. 54.2% were female. Most of the participants in this study were students of engineering and medical informatics. Of the participants in this study, 96.4% considered big data analytics necessary, 50.6% were familiar with the benefits of analytics. Lack of awareness, inadequate management, lack of managers' knowledge, lack of expertise, and lack of priority were the most important challenges for students.
Conclusion: Despite the importance and benefits of big data analytics, challenges are a major barrier to use that need to be addressed.
Relationship Between Shift Work and Lipid Profiles: A Prospective Cohort Study with Application of Ordinal Multilevel Modeling
Authors: Kouselo Amineh , Gholami-Fesharaki Mohammad
Published: August 2020

Introduction: A very limited evidences are available that considered the relationship between Shift Work (SW) and lipid variables.
Objectives: As the importance of this subject, this prospectively cohort study examines the association between SW and Body Mass Index (BMI) and lipid profiles among male workers using multilevel ordinal model.
Methods: This five years prospective cohort study has been conducted in random selected workers (using cluster sampling) who work in Esfahan’s Mobarakeh Steel Company (EMSC) (Iran) between 2011 and 2015.
Results: The study sample included 1626 male workers (mean age=41.5). Among these subjects, 652 (40.01%), 183 (11.3%) and 791 (48.6%) were day workers, weekly rotating shift workers and routinely rotating. After controlling for several confounding variables, except HDL and Cholesterol, the odds ratio for high HDL was decreased by 26% (OR=0.74, P<0.001) and increased for TG by 36% in weekly rotating shift workers compared to day workers.
Conclusion: Since weekly rotating shift workers had higher mean value of TG in their serum compared to day workers, they should limit eating high-fat diets in order to decrease risk of CVD.
SARS Virus Papain-Like Protease: A Mysterious Weapon
Authors: Nejat Reza , Sadr Ahmad Shahir
Published: August 2020

Introduction: Papain-like protease (PLpro) of SARS-CoV in association with 3Chemotrypsin-like protease (3CLpro or Mpro) are two proteases which auto-proteolyze replicase polyproteins pp1a/pp1ab. These polyproteins are translated from ORF1a/ORF1b of the virus genome. Cleavage of pp1a/pp1ab releases nonstructural proteins of the virus which orchestrate viral replication. In addition, PLpro as a deubiquitinase and deISGylase modifies the proteins involved in recognition of the virus by the sensors of host cell innate immunity system. In this manner, the virus reforms the ubiquitination and ISGylation of the cell proteins to progress its own replication without any interference from host cell restrictive strategies against the viruses. Furthermore, PLpro blocks IRF3 activation independent of deubiquinating processes. Besides, PLpro induces pulmonary fibrosis through pathways involving ROS and MAPK.
Conclusion: Inhibition of PLpro allows innate immunity to sense and react against the invasion of SARSCoV and to activate IRF3 to induce type I IFN expression. Thenceforth, proper development and signaling of innate immunity result in a long-term efficient cell/humoral adaptive immunity. Moreover, suppression of PLpro prevents cleavage of nsp3 and hence replication of the virus and through abolishing ubiquitinproteasome/MAPK/ERK- and ROS/MAPK-mediated pathways prevent pulmonary fibrosis.
Legal Protection for Creditors Regarding Working Capital Loan with Expired Hgb Certificate Collateral
Authors: Rudy Darmawan Agung
Published: August 2020

The present study aims to find out the legal protection for creditors regarding debtors’ collateral with expired right to build (hgb) certificate . it was done to find out the attempts can be made by the creditor regarding the debt repayment of debtors with expired hgb certificate. taking place in bri solo baru office, the present study employed normative study. the data were collected through literature review. the data were analyzed through data reduction, data display, and drawing of conclusion. the result of the study showed that: based on article 1 number 11 of law no. 10 of 1998 on the amendment of law no. 7 of 1992 on loan, working capital loan refers to the provision of money or equivalent claim to money based on a loan agreement, when hgb expires, the encumbrance right attached to the land is also annulled. accordingly, the creditor needs to carry out some actions to obtain legal protection. there are two attempts can be done by the creditor regarding the debt repayment of debtors with expired hgb certificates, namely making apht before the ppat, preceded by loan agreement, and renewing hgb certificate, which can be done by the bank or the debtor. auction can be done to maintain the creditor’s assets.
El carcinoma in situ y la radioterapia
Authors: Majluf Tewwfick
Published: August 2020

El problema del carcinoma in situ que asienta en el cuello uterino data de unos 40 a 50 años, y ha cobrado actualidad debido a dos circunstancias básicas:1° Al vehemente anhelo de los cancerólogos de mejorar los resultados del tratamiento del cáncer del cuello uterino, y2° A la introducción del citodiagnóstico.
Fisiología del aparato genital femenino - Conferencia dictada por el profesor Arturo Aparicio J. en el primer curso de ginecología para post-graduados. Hospital de San Juan de Dios. 1956.
Authors: De Obstetricia y Ginecología Federación Colombiana
Published: August 2020

Iniciamos este ciclo de conferencias con el estudio de la Fisiología femenina, pues es de todos sabido que de su conocimiento detallado, podemos adentrarnos en el estudio de lo patológico o anormal.El viejo aforismo de Van Helmont que sintetizaba en el útero toda la esencia de la mujer, modificado más tarde por Chéreau en el sentido de concederle toda la primacia al ovario, ha sido reemplazado en nuestros días por Blair Bell que al decir: "Propter secretiones internas mullier est quod est", sintetiza, a nuestra manera de sentir, todo el progreso alcanzado por nuestra especialidad en las últimas décadas.
Rolf Neth and Russia
Authors: Belogurova Margarita B. , Zubarovskaya Ludmila S.
Published: August 2020

Rolf Neth was also eager to keep scientific borders open and established early connections with scientists from Eastern Europe, particularly the Soviet Union, during the cold war. After the Chernobyl accident (April 1986) a number of doctors and scientists (e.g., R. P. Gale and P. Terasaki) arrived to Moscow within several days, in order to assist Russian doctors by attempting bone marrow transplantation in severely irradiated patients. To study long-term effects of Chernobyl accident, the affected areas of Ukraine and Belarus required well-arranged medical surveillance which was established by international collaboration of European scientists. Professor Rolf Neth has undertaken great efforts to develop appropriate medical infrastructure in radioactively contaminated areas and to organize appropriate laboratory facilities, mostly, for pediatric healthcare
Urban Design Strategy from the Perspective of Low-Carbon City Planning
Authors: Qian Wei
Published: August 2020

The economy growth has improved the development of cities. In cities' continuous development and construction process, carbon emissions are also gradually increasing, causing serious environmental pollution and energy shortage. At present, low-carbon urban planning and design has become the demand of contemporary urban construction, and sustainable low-carbon economy has become the inevitable choice of urban planning. Based on this, this article briefly introduces the concept of low-carbon city planning and the principles of urban design from the perspective of low-carbon city. By analyzing the existing problems in current urban planning, this article proposes urban design strategies from the view of low-carbon city planning, seeking to make contributions to the improvement of urban planning levels.
Obraz Longobardów w "Liber Pontificalis". Od inwazji na Italię do upadku królestwa (568/569–774)
Authors: Dawczyk Maciej
Published: August 2020

Artykuł dotyczy obrazu Longobardów w Liber Pontificalis, kronice pontyfikatów papieży, reprezentującej punkt widzenia biskupów Rzymu i ich otoczenia. W biogramach papieży z końca VI w. Longobardowie pojawiają się stosunkowo często, jako najeźdźcy pustoszący Italię. Jednak ze względu na ogólnie lakoniczny i sprawozdawczy charakter tych vitae informacje dotyczące ludu są krótkie i pozbawione wyraźnych cech retorycznych. W biogramach z VII w. Longobardowie są nieobecni. Związane jest to najprawdopodobniej z faktem, że w tym czasie przestali stanowić dla Rzymu bezpośrednie zagrożenie. Longobardowie stali się ponownie przedmiotem zainteresowania autorów biogramów papieży w VIII w., wraz ze wznowieniem longobardzkiej presji militarnej. Biogramy z tego okresu są bardzo rozbudowane literacko i skupiają się głównie na poczynaniach władców longobardzkich. Obraz królów jest dość zróżnicowany, choć wszyscy traktowani są jako zagrożenie dla Stolicy Apostolskiej. W przypadku Liutpranda odnotowywane są jednak także elementy, które stawiają go w pozytywnym świetle. Podobny jest wizerunek Ratchisa. W skrajnie negatywny sposób przedstawiony został Aistulf, dążący otwarcie do zdobycia Rzymu. Wypadkową wizerunków Liutpranda i Aistulfa jest natomiast obraz ostatniego longobardzkiego króla – Dezyderiusza. Słuszne jest twierdzenie, że za negatywny obraz Longobardów w tym okresie odpowiada w pewnym stopniu brak wcześniejszych intensywnych kontaktów między nimi a papiestwem, potęgujący poczucie obcości i pamięć o zagrożeniu, jakie stwarzali pod koniec VI w. Wydaje się jednak, że kluczowym czynnikiem, wpływającym na wizerunek Longobardów w Liber Pontificalis, była po prostu konieczność przedstawienia w jak najlepszym świetle kolejnych papieży i podejmowanych przez nich działań, co odbywało się kosztem stanowiących zagrożenie Longobardów.
Relacja o słowiańskich Rugianach w średniowiecznych kronikach Helmolda i Saxo Gramatyka
Authors: Galas Iwona
Published: August 2020

Rugianie, zachodniosłowiańskie plemię zamieszkujące wyspę Rugię, utrzymali znaczącą, niezależną od ekspansywnych Niemiec i Danii pozycję aż do XII w. Wówczas Rugia została podbita przez duńskiego króla Waldemara, co nieodłącznie wiązało się z przyjęciem przez pogańskich Rugian chrześcijaństwa. Kroniki Helmolda i Saxo Gramatyka są powszechnie cytowanymi źródłami w rozważaniach dotyczących słowiańskiego pogaństwa i procesu chrystianizacji plemion słowiańskich. To, co stanowi o dużej wartości obu kronik, mimo subiektywnych ocen dokonywanych przez samych autorów, to zakres ich wiedzy na temat połabskich plemion, w tym Rugian – ich znaczenia wśród innych Słowian, roli kapłanów, wyglądu czczonego wśród nich bóstwa. Przede wszystkim jednak kronikarze szczegółowo opisali podbój Rugii przez Duńczyków, co skutkowało przeorganizowaniem władzy na wyspie i umożliwiło rozwój chrześcijaństwa. Jak dotąd tytułowe kroniki pozostają głównymi świadectwami tych wydarzeń.
Hidrotermal Yöntemle Sentezlenmiş Fe3O4 Nanoparçacıklarının Sulardan Nitrat Gideriminde Kullanımı
Authors: Türkyılmaz Mehmet , Küçükçongar Sezen , Özaytekin İlkay
Published: August 2020

Bu çalışmada hidrotermal yöntemle sentezlenmiş Fe3O4 nanoparçacıklarının nitrat giderimindeki etkinliği, ortam şartlarının giderim verimine etkisi, kullanım sonrası geri kazanımı ve yeniden kullanılabilirliği incelenmiştir. Manyetik nanoparçacıkların yüzey morfolojisi, element içeriği, kristal yapısı, spesifik yüzey alanı ve fonksiyonel grupları, taramalı elektron mikroskobu (SEM), geçirimli elektron mikroskobu (TEM), X-ışını kırınımı (XRD), Brunauer-Emmett-Teller (BET) ve Fourier dönüşümlü kızılötesi spektroskopi (FT-IR) analizleriyle aydınlatılmıştır. Kesikli adsorpsiyon çalışmaları sonucunda, optimum ortam şartlarında (30 dk temas süresi, pH 6,9 değeri, 1,2 g/L adsorban dozu ve 100 mg/L başlangıç nitrat konsantrasyonu) %90,26 giderim verimi elde edilmiştir. Desorpsiyon çalışmaları 0,1 M’lık NaCl, NaOH, HNO3 ve HCl ile yapılmış ve NaCl ile tatminkar sonuçlar elde edilmiştir. Fe3O4 ile nitrat adsorpsiyonunun Langmuir izoterm modeliyle daha uyumlu olduğu belirlenmiş ve maksimum adsorpsiyon kapasitesi 86,96 mg/g olarak tespit edilmiştir.
Design a Photobioreactor for Microalgae Cultivation with the IOTs (Internet of Things) System
Authors: Rahmat Ayi , Jaya Indra , Hestirianoto Totok , Jusadi Dedi , Kawaroe Mujizat
Published: August 2020

Internet of Things (IOTs) is an evolution of the concept of internet use that aims to expand the benefits of internet connectivity that is connected continuously with the ability to control remotely (remote control), share data (data sharing), carry out continuous monitoring (real time monitoring) and current (up to date). This research related to the cultivation of microalgae as a source of food and energy of the future, in the design of photobioreactors that are integrated with IoT, so that it can be monitored continuously, controlled and used as a model for the development of greater microalgae cultivation technology. Cultivation in this study was a closed system photobioreactor, will produce microalgae that are not contaminated by external contaminants, growth analysis can be done based on the parameters that influence it, including the cultivation room temperature, lighting level (luminance), and the color of water in the photosynthesis process of microalgae, and also control of water circulation. Visualization of controlled parameters includes, temperature parameters, light intensity, water color changes. The observed parameters will be displayed in a graphical user interface (GUI) in real time using the internet. The advantages of this system can see the growth of microalgae in detail over time, and obtained raw data that can be processed for various research purposes.
GM2 Gangliosidoses: Clinical Features, Pathophysiological Aspects and Current Therapies
Authors: Leal Andres Felipe , Benincore-Flórez Eliana , Solano-Galarza Daniela , Garzón Jaramillo Rafael Guillermo , Echeverri-Peña Olga Yaneth , Suarez Diego A. , Alméciga-Díaz Carlos , Espejo-Mojica Angela Johana
Published: August 2020

GM2 gangliosidoses are a group of pathologies characterized by GM2 ganglioside accumulation into the lysosome due to mutations on the genes encoding for the β-hexosaminidases subunits or the GM2 activator protein. Three GM2 gangliosidoses have been described: Tay-Sachs disease, Sandhoff disease, and the AB variant. Central nervous system dysfunction is the main characteristic of GM2 gangliosidoses patients that include neurodevelopment alterations, neuroinflammation, and neuronal apoptosis. Currently, there is not approved therapy for GM2 gangliosidoses, but different therapeutic strategies have been studied including hematopoietic stem cell transplantation, enzyme replacement therapy, substrate reduction therapy, pharmacological chaperones, and gene therapy. The blood-brain barrier represents a challenge for the development of therapeutic agents for these disorders. In this sense, alternative routes of administration (e.g. intrathecal or intracerebroventricular) have been evaluated, as well as the design of fusion peptides that allow the protein transport from the brain capillaries to the central nervous system. In this review, we outline the current knowledge about clinical and physiopathological findings of GM2 gangliosidoses, as well as the ongoing proposals to overcome some limitations of the traditional alternatives by using novel strategies such as molecular Trojan horses or advanced tools of genome editing.
Design Is How We Change the World! Can We Do It in Socially, Environmentally and Economically Acceptable Ways? Synthesizing Design Tools for This Utopian Concept
Authors: Ponnambalam Kumaraswamy , Seifi Abbas , Mousavi Jamshid
Published: August 2020

Since the beginning, humans advanced their civilization by making better tools to improve their lives. Tools and products were designed for better living considering manufacturing issues, cost and time as predominant criteria. It has become clear that not considering environment and society, both at local/global levels, has now become a major impediment affecting living conditions on a large portion of the Earth and in many societies. Design methodologies should lead to creative solutions with consideration to engineering and economics for practicality but also to environmental and social constraints for sustainability. We propose a comprehensive design methodology based on multidisciplinary design to include the knowledge of humanities, environmentalists, science and engineering, and allowing for experts’ inputs from these areas to provide a holistic approach to engineering design . For example, experts in humanities are expected to interact with stakeholders to evaluate their value systems to provide guidance for the design. The methodology that we synthesize is new and combines (i) Societal level impacts at all scales, (ii) Environmental impacts and (iii) Engineering design with economic impacts, including uncertainty considerations. The proposed design methodology is called Social-Environmental-Economical-Engineering Framework (SEEEF). It can utilize concepts and tools such as Circular Design, Doughnut Economics, design based on environmental life cycle analysis, among others. SEEEF is quantity based and provides steps for evaluating any project or product in an objective manner and will help train engineers in design for sustainability. It also provides non-engineers with a significant role in design to increase their understanding of the hard constraints of engineering. Ultimately, SEEEF allows society to take an informed decision considering short/long term and local/global impacts of the design and the pertinent uncertainties.
Assessing the Level of Mental Health of Medical Staff at a Private Hospital at the Time of Corona Virus Pandemic
Authors: alimoradi hadi , nazari mahsa , jafari nodoushan reza
Published: August 2020

Introduction: Corona epidemic and quarantine enforcement, various effects on the psychological and social aspects of the population has left. The aim of this study is to investigate the relationship between depression, anxiety and relationship with medical staff and mental health is caused by corona. Methods: For this purpose, samples of 650 health personnel of private hospitals were selected. Inventory DASS, HADS, and selected social cohesion (Keyes) and the Internet and through social media networks were evaluated. To analyze the data, Pearson correlation and regression analysis were used. Results: The results showed that straw anxiety corona) to negative (and social cohesion caused by corona) to positive (mental health correlates. It was also found that anxiety and social cohesion caused by corona, respectively 47 and 26 percent predict changes in mental health. Conclusion: These results show the positive and negative effects of psychosocial interventions in quarantine and it have practical implications in the development of the epidemic crisis is Corona.
Nasal Polyposis: Insights in Epithelial-mesenchymal Transition and Differentiation of Polyp Mesenchymal Stem Cells
Authors: Chiarella Emanuela , Lombardo Nicola , Lobello Nadia , Aloisio Annamaria , Aragona Teodoro , Pelaia Corrado , Scicchitano Stefania , Bond Heather M. , Mesuraca Maria
Published: August 2020

Chronic rhinosinusitis is a common inflammatory disease of paranasal sinuses, which causes rhinorrhea, nasal congestion and hyposmia. The genetic predisposition or the exposure to irritants can sustain the inflammatory response and the development of nasal polyposis. Nasal polyps are benign and teardrop-shaped growths that project in the nasal cavities and originate from the ethmoid sinuses. This inflammatory process is associated with high expression of IL-5 cytokine and infiltration of eosinophils. Humanized monoclonal antibodies targeting IL-5 or its receptor, represent a therapeutic strategy in the treatment of nasal polyposis in combination with corticosteroids. The molecular pathogenesis of nasal polyps in CRS patients is associated to the epithelial-mesenchymal transition (EMT), a process in which epithelial cells lose their typical phenotype acquiring a mesenchymal phenotype. TGFβ/SMAD, ERK, and Wnt/β-catenin pathways are altered in EMT during the nasal tissue remodeling. miRNA and inhibitor molecules targeting these altered signaling pathways are able to interfere with EMT; which could lead to alternative therapies. Nasal polyps are an alternative source of mesenchymal stem cells which can be easily isolated from surgical biopsies. A molecular understanding of the biology of PO-MSCs will contribute to delineating inflammatory process underlying the development of nasal polyps.
Differences between Women and Men Regarding the Security Measures Required of the Hotel Sector to Deal with COVID-19
Authors: Lenis Escobar Alexandra , Rueda López Ramón , Menor Campos Antonio , López-Felipe Teresa
Published: August 2020

The tourism sector in general and the hotelier in particular face the challenge of managing appropriate measures to deal with the covid-19 pandemic. In this sense it is useful to know what the measures are most demanded by the clientele. This research, by analyzing the variance (ANOVA) of a factor concluded that women are more demanding than men in terms of the level of demand in relation to the measures to be taken in hotels. This, as a practical application, allows to know more accurately the expectations, demands and demands of the client segmented by sex, in order to satisfy and improve the tourist experiences.
Environmental Urban Plan for Failaka Island, Kuwait: A Study in Urban Geomorphology
Authors: Hassan Ahmed , Almatar Muhammad G , Torab Magdy , Allen Casey D
Published: August 2020

Failaka Island, located in the far east of Kuwait Bay, is about 20 km from the State of Kuwait’s coast, and represents a focal point for regional geography and history, with pristine beaches and archaeological sites dating to the Bronze, Iron, Hellenistic, Christian and Islamic periods. According to environmental data and in coordination with local authorities to develop an urban plan, the island is set to become the first tourist destination for the State of Kuwait. To achieve the Vision of Kuwait 2035, one of the planning objectives focuses around Urban Planning for the Establishment of Environmental Cities that Achieve (UPEECA) environmental sustainability criteria. The paper then, aims to propose the environmental urban plan for Failaka Island. Based around Environmental Analytical Hierarchical Processes (EAHP), and using the Field Calculator and ModelBuilder functions in ArcGIS, this research centres on the feasibility of carrying out an urban plan using suitability modelling that includes four factors and 13 criteria covering the island’s ecological and human composition. This study utilizes both remote sensing (UAVs for 3D imaging) and field study (ground truthing) to identify changes in land use and land cover – such as using sample analysis of the historical sites and soils for tracing evidence and creating/updating a soil map – and create the first GIS database for the island that can lead to generating a suitability model.
Monte Carlo Simulation of the UK’s First EPR Nuclear Reactor Startup Core Using Serpent
Authors: Li Jinfeng
Published: August 2020

Computationally modelling a nuclear reactor startup core for a benchmark against the existing models is highly desirable for an independent assessment informing nuclear engineers and energy policymakers. This work presents a startup core model of the UK’s first Evolutionary Pressurised Water Reactor (EPR) based on Monte Carlo simulations of particle collisions using Serpent 2, a continuous-energy Monte Carlo reactor physics burnup code. Coupling between neutronics and thermal-hydraulic conditions with the fuel depletion is incorporated into the multi-dimensional branches, obtaining the thermal flux and fission rate (power) distributions radially and axially from the three dimensional (3D) single assembly level to a 3D full core. Shannon entropy is employed to characterise the convergence of the fission source distribution, with 3 billion neutron histories tracked by parallel computing. Source biasing is applied for the variance reduction. Benchmarking the proposed Monte Carlo 3D full-core model against the traditional deterministic transport computation suite used by the UK Office for Nuclear Regulation (ONR), a reasonably good agreement within statistics is demonstrated for the safety-related reactivity coefficients, which creates trust in the EPR safety report.
Pengujian Performa Jaringan Syaraf Tiruan Backpropagation Pada Model Pengenalan Tanda Tangan
Authors: Lisdawati Ariani , Wibowo Yunanto Prasetyo , Widodo
Published: August 2020

Tanda tangan seseorang sering berubah-ubah setiap waktu. Perubahan ini menyangkut posisi, ukuran maupun faktor tekanan tanda tangan. Saat ini tanda tangan banyak digunakan sebagai sistem identifikasi untuk mengenali seseorang. Tekstur citra tanda tangan yang unik pada setiap orang dapat dianalisis untuk diidentifikasi. Dengan menggunakan jaringan syaraf tiruan metode backpropagation dapat melihat performa pada pola identifikasi tanda tangan. Pada penelitian ini digunakan metode jaringan syaraf tiruan perambatan balik (backpropagation). Proses pelatihan yang dilakukan adalah menentukan bobot awal sistem, menentukan target keluaran sebagai patokan pelatihan menyesuaikan keluaran, melakukan perbaikan bobot sampai kesalahan yang terhitung lebih kecil daripada kesalahan toleransi. Perbaikan bobot dilakukan dengan melakukan umpan balik sinyal keluaran ke lapis tersembunyi dan lapis masukan. Bobot terakhir yang diperoleh disimpan pada basis data, yang kemudian akan digunakan pada proses pengujian. Selain itu, pengujian dilakukan untuk mengetahui tingkat keberhasilan pengenalan data yang dimasukkan setelah melewati tahap pelatihan. Penelitian ini menggunakan 3 skenario yaitu nasabah, non nasabah dan K-cross Validation. Pada nasabah digunakan 80 citra tanda-tangan yang terdiri atas 2 orang nasabah. Pada non nasabah digunakan 162 tanda tangan yang terdiri atas 9 orang non nasabah. Dan pada k-cross validation menggunakan seluruh subjek baik nasabah maupun non nasabah. Dari penelitian diperoleh kesimpulan pada kasus nasabah memiliki performasebesar  61%, untuk kasus non nasabah 69% dan k-cross validation 51%.
Sistem Informasi Nilai Siswa Berbasis Web di SMK Karya Guna Jakarta
Authors: Niroha Muhammad Lomo , Sugiyanta Lipur , Djaohar Mochammad
Published: August 2020

Sistem informasi nilai siswa berbasis web merupakan suatu sistem yang memberikaninformasi laporan nilai siswa secara online yang berupa laporan nilai serta informasi datasiswa yang bersangkutan dengan berbasiskan web sehingga membantu kecepatan dankualitas dalam penyampaian informasi. Permasalahan yang terjadi dalam pengolahan nilaisiswa di SMK Karya Guna Jakarta saat ini masih bersifat konvensional, dimana siswa danwali siswa hanya bisa melihat hasil dari kemampuan siswa tersebut pada akhir masapembelajaran atau yang kita kenal dengan istilah pembagian raport siswa. Penelitian inibertujuan untuk membangun suatu sistem informasi nilai yang mempermudah pengecekan,pencatatan dan laporan data nilai siswa yang terkomputerisasi. Dengan berbasiskan webmaka informasi data nilai siswa dapat diakses kapan saja. Sistem menggunakan multiuseryang terdiri dari administrator, guru, orang tua dan siswa. Metode yang digunakan adalahsalah satu metode pengembangan perangkat lunak, yaitu metode waterfall. Program yangdihasilkan dalam sistem ini adalah sistem informasi nilai siswa berbasis web denganmenggunakan bahasa pemrograman PHP dan database MySQL.
Perbandingan Model Pembelajaran Aktif, Inovatif, Kreatif, Efektif, Menyenangkan Dengan Model Pembelajaran Kooperatif Tipe Team Assisted Individualization Terhadap Hasil Belajar Simulasi Digital Pada Siswa Kelas X SMK Negeri 34 Jakarta
Authors: Lusandi Meyvi , Hanafi Ivan , Sastrawijaya Yuliatri
Published: August 2020

Penelitian ini bertujuan untuk mengetahui perbedaan model pembelajaran Aktif, Inovatif, Kreatif, Efektif, Menyenangkan (PAIKEM) dengan pembelajaran Kooperatif tipe Team Assisted Individualization (TAI) terhadap hasil belajar siswa pada mata pelajaran Simulasi Digital Kelas X Multimedia dan Kelas X Listrik Di SMKN 34 Jakarta. Penelitian dilakukan di SMKN 34 Jakarta, dilaksanakan pada bulan April - Juni 2016. Penelitian ini menggunakan metode quasy eksperimen, diberikan perlakuan terhadap kedua kelas dengan perlakuan berbeda. Pengambilan sampel menggunakan teknik purposive sampling. Untuk kelas eksperimen diterapkan di kelas X Multimedia menggunakan model pembelajaran PAIKEM dan kelas kontrol diterapkan di kelas X Listrik menggunakan model pembelajaran Kooperatif tipe TAI. Masing-masing kelas terdiri dari 30 siswa. Untuk mendapatkan data penelitian ini dilaksanakan tes awal dan tes akhir untuk mengukur kemampuan kognitif dengan tes pilihan ganda. Hasil penelitian didapatkan siswa yang diterapkan model pembelajaran PAIKEM mendapatkan nilai rata-rata 83,26, sedangkan siswa yang diterapkan model pembelajaran Kooperatif tipe TAI mendapatkan nilai rata-rata 79,04. Sehingga dapat disimpulkan bahwa terdapat perbedaan hasil belajar simulasi digital menggunakan model pembelajaran PAIKEM lebih tinggi dari pada model pembelajaran Kooperatif tipe TAI.
Perbandingan Desain Komunikasi Visual Berbasis Brosur dan Video Sebagai Media Promosi Dapur Lamda di Cisauk-Tangerang
Authors: Natasha Bethanyna , Wibowo Yunanto Prasetyo , Oktaviani Vina
Published: August 2020

Tujuan penelitian ini adalah merancang dan membuat media promosi yang sesuai dengan kriteria, konsep, dan prinsip-prinsip desain komunikasi visual sebagai bentuk produk desain komunikasi visual untuk mempromosikan Dapur Lamda dan mengetahui perbandingan media promosi berbasis brosur dan video terhadap Dapur Lamda. Metodologi penelitian yang digunakan adalah Rekayasa Teknik yang dilakukan ke dalam beberapa tahapan seperti perancangan dan pembuatan brosur dan video. Dilakukan observasi terhadap pengunjung Dapur Lamda untuk melihat perbandingan antara brosur dan video yang lebih menarik minat untuk mengunjungi Dapur Lamda. Dari observasi yang dilakukan, diperoleh hasil perhitungan untuk brosur sebesar 0.27 dan untuk video sebesar 0.72. Terlihat perbandingan antara media promosi berbasis video dan brosur terhadap selektivitas Dapur Lamda. Berdasarkan perhitungan dengan menggunakan presentase Guttman maka media promosi berbasis brosur dapat dikatakan “cukup” menarik masyarakat sedangkan media promosi berbasis brosur dapat dikatakan “sangat baik” menarik masyarakat untuk mengunjungi Dapur Lamda. Media promosi berbasis video sangat unggul menarik perhatian pengunjung Dapur Lamda dibandingkan media promosi berbasis brosur. Namun tidak menutup kemungkinan bahwa media promosi brosur juga masih diminati sebagian masyarakat.
Pengembangan Web Service Penerimaan Mahasiswa Baru Pascasarjana Universitas Negeri Jakarta Tahun Ajar 2017/2018
Authors: Duskarnaen M. Ficky , Praditya Hendrik , Ajie Hamidillah
Published: August 2020

Proses penerimaan mahasiswa baru Pascasarjana Universitas Negeri Jakarta diselenggarakan secara manual oleh beberapa Fakultas dan Program Pascasarjana. Hal tersebut menimbulkan beberapa masalah seperti sulitnya pengumpulan data dan kesulitan untuk melakukan pendaftaran bagi calon mahasiswa yang berasal dari luar Jakarta. Proses penerimaan mahasiswa baru ini akan dilaksanakan setiap tahun, sehingga diperlukan aplikasi berbasis web yang mampu beradaptasi dengan perubahan yang terjadi. Tujuan dari penelitian ini adalah untuk  menghasilkan web service yang dapat digunakan dalam Sistem Penerimaan Mahasiswa Baru Pascasarjana Universitas Negeri Jakarta dan memiliki sifat adaptif terhadap perubahan-perubahan di masa mendatang. Pengembangan web service sistem penerimaan mahasiswa baru Pascasarjana secara online dengan konsep Service Oriented Architecture yang dikembangkan menggunakan framework Laravel dan database MySQL menghasilkan 20 buah endpoint. Pengujian dengan metode unit testing dilakukan terhadap 20 endpoint dengan menggunakan plugin Postman yang ada pada Google Chrome. Hasil pengujian menunjukan bahwa 20 endpoint yang diuji sudah berfungsi dengan baik, dan layak digunakan sebagai backend sebuah web penerimaan mahasiswa baru Pascasarjana Universitas Negeri Jakarta.
Penerapan Konsep User Experience (UX) Pada Perancangan Dashboard Profil Mahasiswa Baru Universitas Negeri Jakarta
Authors: Ajie Hamidillah , Zulfikar Muhammad , Oktaviani Vina
Published: August 2020

Pengolahan data penerimaan mahasiswa baru jenjang Strata 1 dan Diploma 3 di Universitas Negeri Jakarta (UNJ) belum didukung oleh sistem informasi. Hal tersebut menimbulkan beberapa masalah seperti sulitnya mendapatkan informasi untuk bahan evaluasi akreditasi, pemaparan profil program studi, penentuan daya tampung, prediksi penerimaan mahasiswa baru, dan rekapitulasi data mahasiswa baru. Tujuan penelitian ini adalah untuk merancang sebuah dashboard yang dapat menyajikan visualisasi data penerimaan mahasiswa baru dalam bentuk grafik yang sederhana dan menarik. Perancangan dashboard menggunakan konsep User Experience untuk mengembangkan dashboard yang nyaman dan mudah digunakan oleh pengguna. Perancangan dashboard dibuat sampai pada tahap evaluasi dengan mengukur usability dari dashboard kepada calon pengguna. Pengujian usability dilakukan kepada pimpinan dan stakeholder UNJ sebanyak 35 orang. Pengujian usability meliputi tiga hal, yaitu efektivitas, efisiensi, dan kepuasan. Hasil menunjukkan bahwa dari segi efektivitas sebagian besar task berada diatas rata-rata completion rate, dari segi efisiensi memiliki waktu pemakaian produk yang cukup baik pada sebagian besar task dan dari segi kepuasan menunjukkan hasil baik dan sangat baik. Berdasarkan hasil pengujian usability, maka dashboard dapat dikembangkan lebih lanjut untuk digunakan oleh pimpinan maupun stakeholder UNJ.
Culture-Centered Counseling to Growing Culture Empathy in The mids of The Interethnic Conflicts in Indonesia
Authors: Novaili Novaili
Published: August 2020

This research was carried out in Indonesia , a country which can be said to have a wide variety of cultures where it is very possible for conflicts and friction between ethnic groups to emerge. The reason for the researchers who formed the background for this research in Indonesia, is because in reality Indonesia faces a fairly serious problem in terms of relations with ethnicity or groups and becomes a problem that has not yet been resolved . The purpose of this study is to examine the effectiveness of culture-centered counseling to foster cultural empathy in the midst of inter-ethnic conflict in Indonesia , the type of research this is a research experiment with the design of the study one shot-case stud. The subjects of this study were nine people who consisted of various cultural backgrounds . Data were collected using a cultural empathy questionnaire and tested using a one-sample test . Based on the results of the one-sample test the subjects of a counseling model centered on culture to foster cultural empathy in the midst of ethnic conflict in Indonesia are (tcount 66,947> t table 2,306 ). So this finding confirms that counseling centered on culture is effective in fostering cultural empathy amid conflicts between ethnic groups.
ОСОБЕННОСТИ ЭПИДЕМИЧЕСКОГО ПРОЦЕССА COVID-19 В ТЮМЕНСКОЙ ОБЛАСТИ. СООБЩЕНИЕ 1.
Authors: Степанова Татьяна , Ребещенко Анна , Шепоткова Анна , Шарухо Галина , Летюшев Александр , Степанова Ксения , Бакштановская Ирина , Катаева Любовь
Published: August 2020

Вспышка новой коронавирусной инфекции COVID-19 впервые была зафиксирована в г. Ухань, Китайской Народной Республики, в декабре 2019 г. 30 января 2020 года Всемирная организация здравоохранения объявила о чрезвычайной ситуации в области общественного здравоохранения, имеющей международное значение, а 11 марта — пандемией. С 31.01 по 30.06.20 г. в целом по области зарегистрировано 3 155 случаев заболевания COVID-19. По уровню заболеваемости Тюменская область в Уральском регионе занимает четвертое ранговое место и показатель заболеваемости составил 207,7 на 100 тыс. населения, что в 2,1 раза меньше, чем в среднем по РФ (445,7 на 100 тысяч).
The Documentation of Ancestral Caddo Ceramic Vessels from Two Sites in Camp and Upshur Counties in the Cypress Creek Basin in East Texas
Authors: Perttula Timothy
Published: August 2020

In the early 1930s, University of Texas archaeologists obtained ancestral Caddo ceramic vessels from probable burial features at two Caddo sites in Camp and Upshur counties in the Big Cypress Creek basin of East Texas. The vessels from the Sam G. Roberts (41CP8, n=1) and the J. H. Brown (41UR7, n=4) sites in the Texas Archeological Research Laboratory (TARL) vessel collections are fully documented in this article.