bluuebunny/crossref_metadata_2025 huggingface dataset:
Building Student and Family-Centered Care Coordination Through Ongoing Delivery System Design
Authors: Baker Dian , Anderson Lori , Johnson Jody
Published: August 2016

In 2016 the National Association of School Nurses released an updated framework for school nurse practice. One highlight of the new framework is 21st century care coordination. That is, moving beyond basic case management to a systems-level approach for delivery of school health services. The framework broadly applies the term care coordination to include direct care and communication across systems. School nurses are often engaged in efforts to create school health care homes that serve as an axis of coordination for students and families between primary care offices and the schools. Effective care coordination requires that the school nurses not only know the principles of traditional case management but also understand complex systems that drive effective care coordination. The outcome of a system-level approach is enhanced access to services in an integrated health care delivery system that includes the school nurse as an integral member of the school’s health care team. This article presents a comprehensive, system-level model of care coordination for school nurse leadership and practice.
The effect of green leafy and cruciferous vegetable intake on the incidence of cardiovascular disease: A meta-analysis
Authors: Pollock Richard Lee
Published: August 2016

Does the consumption of green leafy vegetables including cruciferous vegetables significantly reduce the incidence of cardiovascular disease? This research question was answered via employing the statistical methods of meta-analysis by synthesizing relevant worldwide studies that address the association between the consumption of green leafy vegetables and risk of incidence of said diseases. All meta-analysis calculations included determination of effect sizes of relative risk, and their respective 95% confidence intervals, heterogeneity of the studies, relative weights for each study, and significance ( p) for each study. Eight studies met the inclusion criteria, which investigated the relationship between the incidences of total cardiovascular disease with the intake of green leafy vegetables. The overall effect size (random effect model) was: RR = 0.842 (95% CI = 0.753 to 0.941), p = 0.002, which indicates a significant 15.8% reduced incidence of cardiovascular disease.
Thioguanine in inflammatory bowel disease: Long‐term efficacy and safety
Authors: Ward Mark G , Patel Kamal V , Kariyawasam Viraj C , Goel Rishi , Warner Ben , Elliott Tim R , Blaker Paul A , Irving Peter M , Marinaki Anthony M , Sanderson Jeremy D
Published: August 2016

Background

Thioguanine (TG) is efficacious in inflammatory bowel disease (IBD), but its toxicity, particularly nodular regenerative hyperplasia (NRH) of the liver, has limited its use. We assessed the long‐term clinical outcomes and safety of TG in patients whom were intolerant or refractory to conventional immunomodulators.

Methods

This is a retrospective, single‐centre study of IBD patients treated with TG from 2001–2013. Response was defined as clinical remission (Harvey–Bradshaw Index < 5 for Crohn’s disease (CD), Simple Clinical Colitis Activity Index < 4 for ulcerative colitis (UC)) without corticosteroids or, if receiving anti‐tumour‐necrosis‐factor (anti‐TNF) therapy, absence of dose escalation. We recorded TG failure, withdrawal and adverse events. Patients were monitored with biochemistry, liver biopsy and/or magnetic resonance imaging (MRI).

Results

54 patients (47 CD and 7 UC) whom received TG (mean dose: 27 mg/d (range: 20–40 mg/d)) as monotherapy (n  = 36) or concomitantly with anti‐TNF (n  = 18) for a median inter‐quartile range of 16 (5–37) months (126 patient‐years of follow‐up). 32 (59%) patients responded to TG at 6 months and 23 (43%) at 12 months. Pancreatitis did not recur amongst the 19 patients with prior thiopurine‐induced pancreatitis. 16 (30%) patients ceased TG due to intolerance or toxicity (four serious); NRH was not observed. 6‐thioguanine nucleotide concentrations did not correlate with efficacy nor with toxicity.

Conclusions

TG was efficacious and well tolerated in one out of two patients who had previously failed conventional immunomodulators. NRH did not occur.
Why children do not attend their appointments: is there a need for an interface between general practitioners and hospitals allowing for the exchange of patients’ contact details?
Authors: Hirani Noorez , Karafillakis Emilie N , Majeed Azeem
Published: August 2016

Objectives

A service evaluation project on the reasons why children do not attend their outpatient appointments.

Design

Analysis of paediatric clinic lists over two consecutive days. Parents of the non-attenders were identified and their reasons for not attending the appointment were elicited using a survey.

Setting

The appointments were scheduled to take place in the Paediatric department at St. Mary’s Hospital, London.

Participants

Of the 201 appointments scheduled, 49 patients did not attend their paediatric appointment. Telephone contact was successful with 35 parents.

Main outcome measures

Parents were asked to verify if their contact details were correct, if they were aware of the appointment and if they had received a reminder. The reasons for non-attendance were explored.

Results

Of the 49 non-attenders, correct contact details were held on file for 24 of the patients (49.0%). Of the 35 parents contacted, 18 were aware (51.4%) of their child’s appointment.

Conclusions

This project revealed that the principal reason for non-attendance is unawareness of the appointment due to incorrect contact details held by the hospital. Potential strategies for reducing non-attendance at this paediatric outpatient clinic include developing a confirmation or reminder system and improved communication with parents. The creation of a new interface between hospitals and GPs would allow hospitals to access patient contact details held by GPs. It would also ensure that hospitals hold up-to-date patient contact details and that appointment details are effectively communicated to parents. The interface would automatically feed through any updated patient details, keeping hospital records current.
The Lazarus phenomenon
Authors: Sahni Vaibhav
Published: August 2016

The Lazarus phenomenon or the unassisted return of spontaneous circulation after cardiac arrest is a grossly underreported phenomenon in medical literature which essentially implies the ‘resurrection’ of an individual after cardiac arrest. Although there have been a handful of such cases reported, the clinical incidence and significance may be underestimated. Because of the presumed infrequency of this condition, there are no studies specifically researching Lazarus phenomenon in scientific literature. This review intends to systematically present current and past knowledge on this rare but definitive phenomenon. Research databases namely Google Scholar, Science Direct, Medline and PubMed were utilized. Only articles which identified cases where the return of spontaneous circulation occurred after cessation of Cardiopulmonary Resuscitation (CPR), and review articles on the entity were included. The mentioned databases were searched using the terms ‘Lazarus phenomenon’, ‘cardiopulmonary resuscitation’ and ‘return of spontaneous circulation’. A literature review was synthesised based on articles meeting the eligibility criteria to better understand the phenomenon of return of spontaneous circulation.
Educational attainment does not modify the effect of educational interventions on blood pressure control: a secondary analysis of data from a randomised trial
Authors: Zhang Kun , Eastwood Dan , Ertl Kristyn , Whittle Jeff
Published: August 2016

Summary

Objectives

To assess whether the effects of community-based educational interventions to improve blood pressure, weight and health behaviours benefit participants with lower educational levels more than those with higher educational levels.

Design

Secondary data analysis.

Setting

Two 12-month community-based educational interventions, one led by trained peers and one delivered by health professionals.

Participants

A total of 403 hypertensive individuals, grouped by education (high school or less; 1–3 years college; 4 + years college).

Main outcome measures

Blood pressure, weight, physical activity and fruit and vegetable intake.

Results

We found that changes in blood pressure, weight and physical activity were similar across education levels; college graduates consumed more daily servings of fruits and vegetables at baseline (3.7 versus 3.6 for those with 12–15 years and 3.1 for those with < 12 years, p = 0.0112), and increased intake more after the intervention (+0.4 versus −0.1 and −0.1, p = 0.0142). The two methods of delivery – peer-led versus professional – had similar effects on all measures.

Conclusions

We conclude that educational interventions, whether delivered by peers or professionals, may improve chronic disease self-management among participants but do not confer greater benefits on participants with lower educational levels.
Education as a Resource of Social Innovation
Authors: Parziale Fiorenzo , Scotti Ivano
Published: August 2016

Focusing on the Italian context, this research aims to analyze the relationship between investment in education and economic development through a critical exam of the human capital theory. This paradigm is compared with the social investment paradigm, particularly the Esping-Andersen’s thesis, which seems more useful to unfold the link between social stratification and education level as a resource of social innovation. From this standpoint, our hypothesis is that educational policies have positive effects on the economic system if they are oriented to reduce socio-economic inequalities increasing the rate of social inclusion, which can promote a wider social innovation.
Teaching about the Holocaust in Israel: A Pedagogical Approach Adopted by the Israeli Ministry of Education
Authors: Kaminka Eyal
Published: August 2016

Holocaust education in any setting requires a careful approach, taking into consideration the cultural sensitivities of the target audiences, local history and current trends. In Israel, where Holocaust education has been created and developed over decades to produce models used around the world, this approach can be examined using the prism of the nationally instituted curriculum. The following article presents the rationale and ramifications of Holocaust education in Israel, as well as principles and suggestions to be considered in Holocaust education world over.
EKLF/KLF1-regulated cell cycle exit is essential for erythroblast enucleation
Authors: Gnanapragasam Merlin Nithya , McGrath Kathleen E. , Catherman Seana , Xue Li , Palis James , Bieker James J.
Published: August 2016

Key Points

EKLF-null erythroid cells completely fail to enucleate due to a block at the orthochromatic stage of differentiation. EKLF regulation of cell cycle inhibitor proteins is critical for nuclear expulsion; reintroduction of these targets is sufficient for rescue.
Grey matter atrophy in prodromal stage of dementia with Lewy bodies and Alzheimer’s disease
Authors: Blanc Frederic , Colloby Sean J. , Cretin Benjamin , de Sousa Paulo Loureiro , Demuynck Catherine , O’Brien John T. , Martin-Hunyadi Catherine , McKeith Ian , Philippi Nathalie , Taylor John-Paul
Published: August 2016

Background

Little is known about the patterns of brain atrophy in prodromal dementia with Lewy bodies (pro-DLB).

Methods

In this study, we used SPM8 with diffeomorphic anatomical registration through exponentiated lie algebra to measure grey matter (GM) volume and investigate patterns of GM atrophy in pro-DLB (n = 28) and prodromal Alzheimer’s disease (pro-AD) (n = 27) and compared and contrasted them with those in elderly control subjects (n = 33) (P ≤ 0.05 corrected for family-wise error).

Results

Patients with pro-DLB showed diminished GM volumes of bilateral insulae and right anterior cingulate cortex compared with control subjects. Comparison of GM volume between patients with pro-AD and control subjects showed a more extensive pattern, with volume reductions in temporal (hippocampi and superior and middle gyri), parietal and frontal structures in the former. Direct comparison of prodromal groups suggested that more atrophy was evident in the parietal lobes of patients with pro-AD than patients with pro-DLB. In patients with pro-DLB, we found that visual hallucinations were associated with relative atrophy of the left cuneus.

Conclusions

Atrophy in pro-DLB involves the insulae and anterior cingulate cortex, regions rich in von Economo neurons, which we speculate may contribute to the early clinical phenotype of pro-DLB.
President's Page
Authors: Cambois Guillaume
Published: August 2016

SEG has done quite a bit of soul-searching this year, most notably with President John Bradford launching a formal strategic-planning exercise at the beginning of his tenure. Timing was excellent as Dorsey Morrow had just joined SEG as its new executive director, and the oil and gas market was taking a turn for the worse. Through a series of interviews, surveys, and workshops, SEG sought to develop a new strategy that would play to SEG's historic strengths while also casting an eye toward the future. The outcome, which was presented by President-Elect Bill Abriel at the May meeting of the SEG Board of Directors, signals a significant shift of focus for SEG.
Modified FOLFOX6 With or Without Radiation Versus Fluorouracil and Leucovorin With Radiation in Neoadjuvant Treatment of Locally Advanced Rectal Cancer: Initial Results of the Chinese FOWARC Multicenter, Open-Label, Randomized Three-Arm Phase III Trial
Authors: Deng Yanhong , Chi Pan , Lan Ping , Wang Lei , Chen Weiqing , Cui Long , Chen Daoda , Cao Jie , Wei Hongbo , Peng Xiang , Huang Zonghai , Cai Guanfu , Zhao Ren , Huang Zhongcheng , Xu Lin , Zhou Hongfeng , Wei Yisheng , Zhang Hao , Zheng Jian , Huang Yan , Zhou Zhiyang , Cai Yue , Kang Liang , Huang Meijin , Peng Junsheng , Ren Donglin , Wang Jianping
Published: August 2016

Purpose

Total mesorectal excision with fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy is a standard treatment of locally advanced rectal cancer. This study investigated the addition of oxaliplatin with and without preoperative radiotherapy.

Methods

In this multicenter, open-label, phase III trial, we randomly assigned (1:1:1) Chinese adults (age 18 to 75 years) with locally advanced stage II/III rectal cancer to three treatments: five 2-week cycles of infusional fluorouracil (leucovorin 400 mg/m2, fluorouracil 400 mg/m2, and fluorouracil 2.4 g/m2 over 48 h) plus radiotherapy (46.0 to 50.4 Gy delivered in 23 to 25 fractions during cycles 2 through 4) followed by surgery and seven cycles of infusional fluorouracil, the same treatment plus intravenous oxaliplatin 85 mg/m2 on day 1 of each cycle (modified FOLFOX6 [mFOLFOX6]), or four to six cycles of mFOLFOX6 followed by surgery and six to eight cycles of mFOLFOX6. Random assignment was performed by using computer-generated block randomization codes. The primary end point was 3-year disease-free survival. Secondary end points of histopathologic response and toxicity are reported.

Results

A total of 495 patients were enrolled from June 2010 to February 2015; 475 were evaluable (fluorouracil-radiotherapy, n = 155; mFOLFOX6-radiotherapy, n = 157; mFOLFOX6, n = 163). In the fluorouracil-radiotherapy, mFOLFOX6-radiotherapy, and mFOLFOX6 groups, the rate of pathologic complete response (pCR) was 14.0%, 27.5%, and 6.6%, and downstaging (ypStage 0 to 1) was achieved by 37.1%, 56.4%, and 35.5% of patients, respectively. Higher toxicity and more postoperative complications were observed in patients who received radiotherapy.

Conclusion

mFOLFOX6-based preoperative chemoradiotherapy results in a higher pCR rate than fluorouracil-based treatment. Perioperative mFOLFOX6 alone had inferior results and a lower pCR rate than chemoradiotherapy but led to a similar downstaging rate as fluorouracil-radiotherapy, with less toxicity and fewer postoperative complications.
Improved Metastasis-Free and Survival Outcomes With Early Salvage Radiotherapy in Men With Detectable Prostate-Specific Antigen After Prostatectomy for Prostate Cancer
Authors: Stish Bradley J. , Pisansky Thomas M. , Harmsen William S. , Davis Brian J. , Tzou Katherine S. , Choo Richard , Buskirk Steven J.
Published: August 2016

Purpose

To describe outcomes of salvage radiotherapy (SRT) for men with detectable prostate-specific antigen (PSA) after radical prostatectomy for prostate cancer and identify associations with outcomes.

Patients and Methods

A total of 1,106 patients received SRT between January 1987 and July 2013, with median follow-up 8.9 years. Outcomes were estimated using Kaplan-Meier for overall survival (OS) and cumulative incidence for biochemical recurrence (BcR), distant metastases (DM), and cause-specific mortality (CSM). Variable associations with outcomes used Cox or Fine-Gray methods, as appropriate. Multiple variable analyses used backward selection with P < .05 for retention.

Results

In multiple variable analyses, pathologic tumor stage, Gleason score, and pre-SRT PSA were associated with BcR, DM, CSM, and OS; androgen suppression and SRT doses > 68 Gy were associated with BcR; and age was associated with OS. Each pre-SRT PSA doubling increased significantly the relative risk of BcR (hazard ratio [HR], 1.30; P < .001), DM (HR, 1.32; P < .001), CSM (HR, 1.40; P < .001), and all-cause mortality (HR, 1.12; P = .02). Using a pre-SRT PSA cutoff ≤ 0.5 versus > 0.5 ng/mL, 5-year and 10-year cumulative incidences for BcR were 42% versus 56% and 60% versus 68% ( P < .001), DM 7% versus 14% and 13% versus 25% ( P < .001), CSM 1% versus 4% and 6% versus 13% ( P < .001), and OS of 94% versus 92% and 83% versus 73% ( P > .05).

Conclusion

SRT outcomes are in part affected by factors associated with prostatectomy findings but may be positively affected by using SRT at lower PSA levels, including reductions in BcR, DM, CSM, and all-cause mortality. These findings argue against prolonged monitoring of detectable postprostatectomy PSA levels that delay initiation of SRT.
In Defense of the NSF Economics Program
Authors: Moffitt Robert A.
Published: August 2016

The NSF Economics program funds basic research in economics across all its disparate fields. Its budget has experienced a long period of stagnation and decline, with its real value in 2013 below that in 1980 and having declined by 50 percent as a percent of the total NSF budget. The number of grants made by the program has also declined over time, and its current budget is very small compared to that of many other funders of economic research. Over the years, NSF-supported research has supported many of the major intellectual developments in the discipline that have made important contributions to the study of public policy. The public goods argument for government support of basic economic research is strong. Neither private firms, foundations, nor private donors are likely to engage in the comprehensive support of all forms of economic research if NSF were not to exist. Select universities with large endowments are more likely to have the ability to support general economic research in the absence of NSF, but most universities do not have endowments sufficiently large to do so. Support for large-scale general purpose dataset collection is particularly unlikely to receive support from any nongovernment agency. On a priori grounds, it is likely that most NSF-funded research represents a net increase in research effort rather than displacing already-occurring effort by academic economists. Unfortunately, the empirical literature on the net aggregate impact of NSF economics funding is virtually nonexistent.
Reliability evaluation of machines based on their operation risks
Authors: Khozyaev Igor A. , Koledov Leonid V. , Vazhenin Vladislav A
Published: August 2016

The work objective is to develop a technique of evaluation and forecasting of the complex systems reliability based on the statistic simulation of their operation. A method of risks inherent in the lost benefit is used. Dependences for determining failure losses under the system operation according to the degree of its reliability are offered. A simulation program taking into account risks of reliability - “Reliabilify” - is worked out. The developed method verification is based on the performance simulation of the feed ingredient cutter, such as U17-UKI. The results obtained reflect real processes occurring in the course of the technical objects operation. The method is fully formalized and can be used for estimating the reliability of any engineering system.
Evaluation of dynamic stability in monitoring control system by the road machines technical-and-economic efficiency
Authors: Mandrovskiy Konstantin P.
Published: August 2016

The study objective is to review the prerequisites for reducing the time of transport movements of the road-building machinery. On the basis of the information received, the corresponding recommendations used in the performance control system and technical audit can be elaborated. Shortcomings of the existing monitoring systems are marked. It is shown that their application to improve the technical-and-economic efficiency of the road vehicles does not allow achieving the controlled results. The technical-and-economic effect should be assessed by the unit cost criterion taking into account the cost for ownership. To calculate such a criterion, it is necessary to have the source information that can be obtained by monitoring. At a minimum criterion, there are work performance and operating quality time limits. The possibility of implementing restrictions on the time performance which largely depends on the machine transportation operations time is considered. Transport operations, in turn, are determined by the stability level, so to elaborate recommendations on reducing the transport operations time it is necessary to evaluate the stability by special calculating formulas. Various options for calculating are considered, the option of differential rocking equations is selected. It is noted that the working process is better described by the loading workflow diagrams, so they should be built on the basis of differential equations. An example of the loading diagram construction for a front loader is given. The application of loading diagrams to elaborate recommendations on reducing the transport operations time is shown
The Mechanism of Innovative Structures Creation Basing on Small Innovative Enterprises
Authors: Сыбачин  , Sybachin S. , Гончаренко  , Goncharenko L. , Ордов  , Ordov K. , Хачатуров  , Khachaturov G.
Published: August 2016

Th is article discusses the mechanism of creation of innovation structures of educational organization. The

legislative framework of open innovative enterprise is described. Development of the considered mechanism is proposed.

An alternative mechanism is presented.
Conceptual Bases of Realization of Professional Orientation Work of Higher Education Institutions in the Region
Authors: Никулина  , Nikulina Yu.
Published: August 2016

Relevance of work is caused by the fact that now the integrated approach to system of professional orientation work with youth starting with the entrant becomes one of important tasks for higher education institutions and finishing the graduate taking into account their personal opportunities and abilities, and also a state and prospects of development of regional economy and labor market. In article functions of the main subjects on career guidance of youth in general are considered and the emphasis for a role of higher education institutions in this direction is placed. Results of research of preferences of entrants are given in the choice of educational services, an assessment of efficiency of professional orientation work in the region, conclusions are drawn. Need of development of the Concept of professional orientation work of higher educational institutions of the Orenburg region with youth is proved. The principles are formulated, the mechanism of realization of professional orientation work is presented and the main directions of improvement of work of higher education institutions of the Orenburg region on career guidance stages are defined.
Report from the "What is Publishing?" (2) Workgroup
Authors: Dolechek Melanie , Farb Sharon E. , Hall Steven , Hemmasi Harriette , Inglis John , Macklin Lisa , Oransky Ivan , Parsons Mark A. , Rodnan Nancy , Tein Andrew
Published: August 2016

OSI2016 Workgroup QuestionWhat do we mean by publishing in today’s world? What should be the goals of scholarly publishing? What are the ideals to which scholarly publishing should aspire? What roles might scholarly publishers have in the future? What scenarios exist where publishers continue to play a vital role but information moves more freely? What impact might these reforms have on the health of publishers? Scholarly societies? Science research? Why?
What is Publishing? (2)
Authors: Dolechek Melanie , Farb Sharon E. , Hall Steven , Hemmasi Harriette , Inglis John , Macklin Lisa , Oransky Ivan , Parsons Mark A. , Rodnan Nancy , Tein Andrew
Published: August 2016

What do we mean by publishing in today’s world? What should be the goals of scholarly publishing? What are the ideals to which scholarly publishing should aspire? What roles might scholarly publishers have in the future? What scenarios exist where publishers continue to play a vital role but information moves more freely? What impact might these reforms have on the health of publishers? Scholarly societies? Science research? Why?
At-Large Workgroup: Themes and Observations
Authors: Andalibi Ali , Carpenter Todd , Collins Nina K. , Delenick Joann C. , Escobar-Alvarez Sindy , Fiore Steve , Gunn William , Gwinn Nancy , Lossau Norbert , Luther Judy , McColgin Dave , Morovati Meredith , Plutchak T. Scott , Sebeok Jessica , Seminara Concetta , Skomal Susan , Ware Mark , Warren John W. , Woolley Mary , Xiao Grace , Zenelis John
Published: August 2016

The At-Large group was the largest and most diverse in terms of stakeholder representation. At-large delegates observed workgroup conversations during the meeting and contributed to these conversations while letting the workgroup teams answer their questions. At-large delegates met during the conference and convened online both before and after the conference in order to develop some high level takeaways based on what they observed. While workgroups focused on answering a particular big question confronting scholarly publishing, at-large delegates had a wide-angle lens on the evolution of these questions and proceedings.
Report from the Evolving Open Solutions (2) Workgroup
Authors: Billings Marilyn , Bobley Brett , McCollough Aaron , Mudditt Alison , Naim Kamran , Pinter Frances , Price Richard , Roche Tony , Sprio Lisa , Vandegrift Micah
Published: August 2016

Are the scholarly publishing tools we’re using today still the right ones? Is the monograph still the best format in the humanities? Is the journal article still best in STM? These products can be difficult to produce and edit, nearly impenetrable to read, and—as in the case of clinical research information—they aren’t necessarily the best-suited formats for capturing every piece of necessary information (like protocols and datasets in medical research) and showing how this information is all connected to other scholarship. What other formats and options are being considered or used? What are the prospects of change? How about the stakeholder universe itself? How are roles, responsibilities and expectations changing (and where might they end up)? Are we “settling” on half-measures or on the best possible solutions?
The Journal Impact Factor and its discontents: steps toward responsible metrics and better research assessment
Authors: Arruda J. Roberto F. , Champieux Robin , Cook Colleen , Davis Mary Ellen K. , Gedye Richard , Goodman Laurie , Jacobs Neil , Ross David , Taylor Stuart
Published: August 2016

A small, self-selected discussion group was convened to consider issues surrounding impact factors at the first meeting of the Open Scholarship Initiative in Fairfax, Virginia, USA, in April 2016, and focused on the uses and misuses of the Journal Impact Factor (JIF), with a particular focus on research assessment. The group’s report notes that the widespread use, or perceived use, of the JIF in research assessment processes lends the metric a degree of influence that is not justified on the basis of its validity for those purposes, and retards moves to open scholarship in a number of ways. The report concludes that indicators, including those based on citation counts, can be combined with peer review to inform research assessment, but that the JIF is not one of those indicators. It also concludes that there is already sufficient information about the shortcomings of the JIF, and that instead actions should be pursued to build broad momentum away from its use in research assessment. These actions include practical support for the San Francisco Declaration on Research Assessment (DORA) by research funders, higher education institutions, national academies, publishers and learned societies. They also include the creation of an international “metrics lab” to explore the potential of new indicators, and the wide sharing of information on this topic among stakeholders. Finally, the report acknowledges that the JIF may continue to be used as one indicator of the quality of journals, and makes recommendations how this should be improved.OSI2016 Workshop Question: Impact FactorsTracking the metrics of a more open publishing world will be key to selling “open” and encouraging broader adoption of open solutions. Will more openness mean lower impact, though (for whatever reason—less visibility, less readability, less press, etc.)? Why or why not? Perhaps more fundamentally, how useful are impact factors anyway? What are they really tracking, and what do they mean? What are the pros and cons of our current reliance on these measures? Would faculty be satisfied with an alternative system as long as it is recognized as reflecting meaningfully on the quality of their scholarship? What might such an alternative system look like?
Report from the Evolving Open Solutions (1) Workgroup
Authors: Bilder Geoffrey , Ghebre Adyam , Kenneway Melinda , Kiley Robert , Kirk Elizabeth , Murphy Paul , Nicholson Joshua , Potter Peter , Salter Matthew , Sander Frank
Published: August 2016

OSI2016 Workgroup QuestionAre the scholarly publishing tools we’re using today still the right ones? Is the monograph still the best format in the humanities? Is the journal article still best in STM? These products can be difficult to produce and edit, nearly impenetrable to read, and—as in the case of clinical research information—they aren’t necessarily the best-suited formats for capturing every piece of necessary information (like protocols and datasets in medical research) and showing how this information is all connected to other scholarship. What other formats and options are being considered or used? What are the prospects of change? How about the stakeholder universe itself? How are roles, responsibilities and expectations changing (and where might they end up)? Are we “settling” on half-measures or on the best possible solutions?
Embargoes
Authors: Campbell Glenorchy , Gordon Gregg , Helmuth Laura , Kingsley Danny , Massant Eric , McCulloch Audrey , McMillan Gail , Peatfield Tony , Riley Ann , Schweitzer Will , Webster Keith
Published: August 2016

In an information system where so much information is destined for subscription journals, the assumption has been that embargoes allow publishers time to recoup their investments, and also allow the press time to prepare news articles about research. Is this assumption warranted? Why or why not? Is the public interest being served by embargoes? What about by embargoes on federally-funded research? Are there any facts or options that haven’t yet been considered to address the concerns animating the embargo solution?
How To Start A War: Eight Cases of Strategic Provocation
Authors: Maddox JD
Published: August 2016

A leader intent on starting a war must develop a compelling narrative for their domestic constituency and the international community.  For some, strategic provocation – defined here as the use of deceptive tactics to instigate violence against one's own state – has been a reliable means of initiating war under the guise of self-defense. Eight cases of strategic provocation reveal a basic pattern of its use, and some possibly unwelcome truths about state leaders' methods.  As international institutions increasingly scrutinize states' interventionist agendas, the use of deceptive narratives is likely to continue. Despite known indicators of strategic provocation operations, warning of such operations has not typically prevented warfare.
Faith, Politics, and the Parable of the Kosher Deli: Explorations of Narrative in a Congressional Hearing
Authors: Kraut Joshua
Published: August 2016

This paper takes a discourse analytic approach in exploring how a short narrative, delivered in the testimony of a panel-witness during a 2011 US congressional hearing investigating potential violations of religious liberty in the Patient Protection and Affordable Care Act (commonly known as “Obamacare”), shapes and reflects the larger political conflict over the legislation.  Exploring the so-called “parable of the kosher deli” from a structuralist, functionalist, and post-structuralist perspective reveals several key elements of how narratives can function in such a context.  The choice of genre not only facilitates communication via a culturally familiar structure, but also positions the communicator reflexively, and in strategic fashion.  This choice also provides an efficient means for glossing over the adversary’s most significant concerns: because parables are abstractions meant to reflect back on real situations, one can choose which elements to incorporate, and which to ignore about those situations in one’s interpretation.            Additionally, I observe how the parable is an effective means for positioning an opposing side (Davies and Harré, 1990), as the narrative takes aim at not only the government, positioned as an illegitimate disciplinarian, and an inappropriate judge, but also at advocates of the legislation generally, characterized as “off-topic” or else blind to the most important issue.  Finally, from a post-structuralist perspective, I note that the narrative, reflecting the general stance of the majority members of committee overseeing the hearing, construes the opposing side as a “generalized other” (Benhabib, 1992), ignoring the role of individual experience, needs, motivations, and desires in the attempt to make a case for broader exemptions to the proposed legislation.  Such a move short-circuited any possibility of “elaboration” (Cobb, 2006) in which both sides might have worked toward a mutually agreeable narrative which contained both of the moral perspectives presented.   ACKNOWLEDGEMENTS:I would like to thank Sara Cobb as well as the editor and two anonymous reviewers for their constructive comments on earlier versions of this manuscript.
Resiliência, stresse parental e sobrecarga de pais de crianças com diagnóstico de anomalia congénita
Authors: Albuquerque Sara , Pereira Marco , Fonseca Ana , Canavarro Maria Cristina
Published: August 2016

O presente estudo teve como objetivo avaliar a adaptação parental (em termos de perceção de sobrecarga e stresse parental), bem como o papel das características de resiliência de pais e mães na adaptação parental. A amostra foi constituída por 45 casais, pais de crianças com um diagnóstico de deficiência/anomalia congénita. O protocolo de avaliação incluiu a Escala de Resiliência para Adultos (ERA), a Escala de Impacto Familiar (EIF) e o Índice de Stress Parental (Forma reduzida) (ISP). Os resultados mostraram que as mães apresentaram valores mais elevados de Distress parental e os pais valores mais elevados na dimensão Interação disfuncional pais‑criança.Relativamente à sobrecarga, não se verificaram diferenças significativas entre mães e pais. Em ambos os progenitores, aresiliência mostrou‑se associada a melhor adaptação. A resiliência materna não se mostrou associada à adaptação paterna, mas constatou‑se que níveis elevados de resiliência paterna se associaram significativamente a melhor adaptação materna. As característicasresilientes revelaram‑se como importantes determinantes na adaptação parental. Estesresultados enfatizam ainda a necessidade não só de avaliar os pais e as mães separadamente, mas também o casal como unidade de análise, e de analisar os recursos parentaise os potenciais efeitos cruzados no desenho de intervenções terapêuticas.
Crise económica e dificuldades familiares: Duas faces da mesma moeda?
Authors: Cunha Diana , Relvas Ana Paula
Published: August 2016

Os meios de comunicação têm promovido a ideia de que a crise económica está fortemente associada a uma deterioração da saúde mental e a consequências familiares importantes. No entanto, esta parece ser uma “verdade” muito pouco estudada em Portugal, apesar de ser quase dogmaticamente assumida. Assim, este estudo analisa uma amostra de pessoas (N = 287) que considera a crise económica o seu principal problema familiar, atendendo às seguintes variáveis: dificuldades familiares (SCORE-15), qualidade da vida familiar (QV),ajustamento conjugal (DAS), satisfação conjugal (EASAVIC), congruência (CE) e sintomas psicopatológicos (BSI). Os resultados mostram que, apesar de a crise afetar a qualidade de vida, os participantes são resilientes em termos do funcionamento familiar, sendo a conjugalidade, a área relacional mais prejudicada. Embora mais tristes e preocupados, os participantes mostram-se emocionalmente saudáveis. Este estudo apresenta algumas limitações, como as características da amostra. Apesar disso, contribui para preencher a lacuna de evidências científicas sobre o impacto da crise económica nas famílias portuguesas, através de uma abordagem mais psicossocial e despatologizante.
Impacto de um programa holístico de reabilitação neuropsicológica na qualidade de vida de pessoas com lesão cerebral adquirida
Authors: Almeida Isabel , Guerreiro Sandra , Martins-Rocha Benedita , Dores Artemisa Rocha , Vicente Selene G. , Barbosa Fernando , Castro-Caldas Alexandre
Published: August 2016

A reabilitação após lesão cerebral adquirida (LCA) pretende aumentar a funcionalidade do indivíduo, promovendo a sua Qualidade de Vida (QdV). O objetivo deste estudo é avaliar o impacto de um programa holístico de reabilitação neuropsicológica (PHRN) nas dimensões da QdV. Participaram 20 pessoas com LCA, média de idades 30 anos (DP = 7.62). Os participantes foram avaliados pré e pós intervenção, com intervalo de seis meses, utilizando-se o Quality of Life After Brain Injury (QOLIBRI). Para a análise usamos o t-test para amostras emparelhadas, com p corrigido para comparações múltiplas. Verificam-se resultados significativos após a intervenção em todas as dimensões: total [t(19) = -4.59, p < .001], cognitiva [t(19) = -2.31, p = .003], self [t(19) =-5.76, p < .001], AVD (atividades de vida diária) [t(19) = -3.18, p = .001], social [t(19) = -1.29, p = .001], emocional [t(19) = -1.85, p = .001], com exceção da dimensão físico [t(19) = -1.78, p = .01]. Os resultados sugerem que a intervenção com o PHRN promove a QdV das pessoas com LCA.
Efficacy, safety, and tolerability of Kedrion 10% IVIG in primary immunodeficiency
Authors: Stein Mark , Nemet Agnes , Kumar Santhosh , Lumry William , Gajek Hartwig , Macchia Roberta , Zamfirova Vladislava , Bergman Garrett , McNeil Donald , Hooper John , Moy James , Pesek Robert , Upton Julia , Shapiro Ralph , Sussman Gordon , Roifman Chaim M.
Published: August 2016

Background: Primary immunodeficiency involving defective antibody formation requires antibody replacement therapy with immunoglobulin products to prevent and reduce infections. Immunoglobulin for intravenous use (IVIG) is a processed blood product with limited availability, and the various marketed IVIG products may have different tolerability among patients. New IVIG products are therefore necessary to offer options to patients and to reduce the risk of a product shortage.

Methods: Forty-five adult and pediatric patients with primary immunodeficiency, documented agammaglobulinemia or hypogammaglobulinemia, and antibody deficiency were enrolled in a prospective, multi-centre, open-label, single-arm historically controlled Phase III study to evaluate the safety, efficacy, and pharmacokinetics of a new 10% IVIG produced by Kedrion.

Results: Forty-four patients completed the study while one withdrew consent. Over the 12-month study period, only 2 episodes of acute serious bacterial infections (both bacterial pneumonias) were recorded, for a mean annual event rate of 0.04 per subject, with an upper one-sided 99% confidence limit of 0.11. Values for all secondary efficacy endpoints were comparable with those in similar studies. The primary safety endpoint was met as the rate of infusions temporally associated (i.e., within 72 hours) with ≥1 adverse event was 16% (upper 95% confidence limit 20.4%). Pharmacokinetics were assessed in 31 patients and found to be comparable with those published for other IVIG products.

Conclusion: Kedrion IVIG 10% is safe, efficacious, and well tolerated by patients with primary immunodeficiency.

Statement of novelty: This report describes the safety, efficacy, and pharmacokinetics of a new IVIG preparation.
Effect of arbuscular mycorrhizal fungi on the potential of three wild plant species for phytoextraction of mercury from small-scale gold mine tailings
Authors: Fiqri A , Utomo W H , Handayanto E
Published: August 2016

A study that was aimed to explore the effects of arbuscular mycorrhizal (AM) fungi inoculation on the potential of wild plant species (Paspalum conjugatum, Cyperus kyllingia, and Lindernia crustacea) for phytoextraction of mercury from small-scale gold mine tailings was conducted in a glasshouse. Each of the plant seedlings was planted in a plastic pot containing 10 kg of planting medium (mixture of tailings and compost; 50%: 50% by weight). Treatments tested were three plant species and doses of AM fungi inoculation, i.e. 0 and 30 spores/plant. At harvest of 63 days, plant shoot and root were analyzed for mercury concentration. The remaining planting media in the pots were used for growing maize for 84 days. The results showed that the most potential plant species for phytoextraction of mercury was Paspalum conjugatum, while the most mercury tolerant plant was Cyperus kyllingia. Without AM fungi inoculation, the highest accumulation of mercury (44.87 mg/kg) was found in the root of Paspalum conjugatum. If AM fungi were inoculated, the highest accumulation of mercury (56.30 mg/kg) was also found in the shoot of Paspalum conjugatum. Results of the second experiment proved that the growth and biomass production of maize after mycophytoextraction by the plant species were higher than those of maize grown on media without mycophytoextraction of mercury.
Baudžiamoji atsakomybė už neveikiant padarytas nusikalstamas veikas – specialiojo nusikalstamos veikos subjekto pareigos veikti šaltiniai
Authors: Kaszewska Katarzyna
Published: August 2016

Straipsnyje apžvelgiamos Lenkijos Respublikos bau­džiamosios teisės mokslininkų pozicijos dėl nevei­kimo sąvokos ir esmės, nurodoma neveikimo sam­prata, remiantis kauzaline, socialine, finaline veikos teorijomis, taip pat neveikimo sampratos, atskaitos tašku laikant teisinio draudimo charakteristikas, be to, neveikimą analizuojant pagal jo lingvistinę ana­lizę.Autorė straipsnyje analizuoja 1997 m. priim­to Lenkijos Respublikos baudžiamojo kodekso 2 straipsnio nuostatas, reglamentuojančias baudžia­mąją atsakomybę už neveikimu padarytas nusikals­tamas veikas, taip pat pateikia specialiojo nusikalsta­mos veikos subjekto teisinius požymius, remdamasi konkrečiais pavyzdžiais pagal Lenkijos Respublikos baudžiamąjį kodeksą. Straipsnyje daug dėmesio ski­riama ir specialiojo subjekto pareigą veikti reglamen­tuojantiems šaltiniams: įstatymams, sutartims, anks­tesniam asmens veikimui. Autorė daro išvadą, kad pirmieji du šaltiniai, atsisakant trečiojo, nors teismų praktikoje ir pripažįstamo, labiausiai užtikrintų nul­lum crimen sine lege principo įgyvendinimą. The following article discuss question of penal liability for omissive offences and concentrates on the subject of a status of a guarantor of not-occurrence the result. In the first part of the article it brings closer an overview of opinions of polish penal law researchers on the nature and definition of an omission. Than the article presents polish regulation of penal liability for omissive offences enclosed in article 2 of Penal Code. After that it describes status of a guarantor in polish penal law. In the end the following paper indicates and describes sources of guarantor’s duty to act, and problems connected with that ca­talogue.
Specialiojo Irako tribunolo funkcionavimas (materialiniai ir procesiniai aspektai)
Authors: Katarzyna Dróżdż D Ominika
Published: August 2016

Straipsnyje analizuojamos Irako specialiojo tribu­nolo, įkurto 2003 m. gruodžio 10 d., statuto nuos­tatos, materialiniai ir procesiniai Tribunolo veiklos aspektai. Nurodoma, kad Statutu įdiegtas stebėtojų ir patarėjų tarptautinės teisės klausimais institutas – keliamas jų veiklos teisinio apibrėžtumo klausimas; apibūdinama Tribunolo jurisdikcija: nuo 1968 m. lie­pos 17 d. iki 2003 m. gegužės 1 d. padarytiems nusi­kaltimams, numatytiems Statuto 11–14 straipsniuo­se, už kuriuos gali būti traukiami tik Irako piliečiai ir nuolatiniai Irako gyventojai, nusikaltimus padarę Irake ir už jo ribų teisti. Nurodoma, kad nėra regla­mentuota asmenų, Tribunolo trauktinų baudžiamo­jon atsakomybėn, amžiaus riba; juridiniai asmenys (pvz., Baath partija) nėra teisiami. Taip pat, lyginant su Tarptautinio karinio tribunolo nuostatomis, Irako specialusis tribunolas negali paskelbti nė vienos gru­pės ar organizacijos kriminaline.Straipsnyje taip pat analizuojami nusikaltimai, už kuriuos gali teisti Irako specialusis tribunolas, lyginamas kitų ad hoc tribunolų veiklos teisinis re­glamentavimas. Autorė, be to, palyginusi Irako speci­aliojo tribunolo statuto ir Romos statuto bei 1949 m. Ženevos konvencijos papildomo protokolo nuostatas, daro išvadą, kad baudimas už kai kuriuos Irako spe­cialiojo tribunolo statute numatytus nusikaltimus būtų nesuderinamas su nullum crimen sine lege, nes tai nėra universaliai tarptautiniu lygiu pripažįstami nusikaltimai; terorizmo nusikaltimo Statute taip pat nenumatyta – tai būtų Irako nacionalinių teismų ju­risdikcijos klausimas.Taip pat teigiama, kad Statuto 11c) punktas turėtų būti traktuojamas kaip novela, nes numato agresiją kaip nusikalstamą veiką.Straipsnyje analizuojamos kaltinamųjų, liudytojų, nukentėjusiųjų teisės procese; pabrėžiama, kad Irako specialiojo tribunolo statute nenumatyta žalos atlygi­nimo instituto, kompensacijos už neteisėtą areštą ar sulaikymą; skiriama dėmesio reguliuojant procesą in absentia, Tribunolo sprendimo peržiūrai. The Iraqi Special Tribunal was established directly by the Iraqi Governing Council on December 10, 2003. The Tribunal has been mandated to try the accused for crimes under international law (genocide, crime against humanity and war crimes) and some violations of Stipulated Iraqi Laws.This article contains an analysis of the provisions of the Statute of the Iraqi Special Tribunal with regard to its material and procedural aspects. The Statute of this Tribunal was created taking for the pattern the Statute of International Criminal Court. However, the opinions of the Iraqis were also taken into account; the Iraqis wanted to have the solely power to exercise jurisdiction of this Tribunal.