bluuebunny/crossref_metadata_2025 huggingface dataset:
Die börsennotierte Aktiengesellschaft als kartellrechtlicher Kronzeuge
Authors: Hübner Leonhard
Published: October 2021

Kronzeugenanträge stellen inzwischen einen wesentlichen Durchsetzungsmechanismus für das europäische und nationale Kartellrecht dar. Häufig fungieren dabei börsennotierte Aktiengesellschaften als Kronzeugen. Die Gesellschaften befinden sich jedoch in einer Konfliktlage zwischen verschiedenen Rechtsgebieten, deren Regelungszwecke sich teils widersprechen. Einerseits zwingt das Kapitalmarktrecht die Gesellschaften als Emittenten zur Ad-hoc-Veröffentlichung von kursrelevanten Insiderinformationen und damit möglicherweise auch zur Veröffentlichung der Stellung eines Kronzeugenantrags. Auf der anderen Seite fordert das Kartellrecht, dass die Gesellschaft die Umstände des Kronzeugenantrags grundsätzlich geheim hält. Daneben besteht auch ein Konflikt zwischen gesellschafts- und kartellrechtlichen Zielsetzungen: Während das Kartellrecht auf einen zügigen und vertraulichen Verlauf des Kronzeugenverfahrens abzielt, setzt das Aktienrecht bei der internen Beratung und Umsetzung des Kornzeugenantrags auf Entschleunigung und offene Kommunikation zwischen den Organen der Gesellschaft. Die beschriebenen Zielkonflikte gilt es mit dem bestehendem Norminstrumentarium aufzulösen.
Flux synthesis, crystal structure and electronic properties of the layered rare earth metal boride silicide Er3Si5–x
B. An example of a boron/silicon-ordered structure derived from the AlB2 structure type
Authors: Babizhetskyy Volodymyr , Jardin Régis , Gautier Régis , Fontaine Bruno , Halet Jean-François
Published: October 2021

The ternary rare earth metal boride silicide Er3Si5–x
B (x = 1.17) was synthesized from the elements using the tin flux method. It crystallizes in a new structure type in the space group R32 (a = 6.5568(1) Å, c = 24.5541(1) Å, Z = 6). The structural arrangement can be derived from the AlB2 structure type with boron/silicon ordering in the layered metalloid substructure made of [Si5B] hexagons. The presence or absence of the boron atoms involved in this ordered structure is discussed on the basis of difference Fourier syntheses and structural analysis, in relation with the binary parent structures AlB2 and Yb3Si5 (Th3Pd5 type). The electronic and bonding properties of Er3Si5–x
B were analyzed and discussed via density functional theory (DFT) calculations and a crystal orbital Hamiltonian population (COHP) bonding analysis.
Determination of Dispersive Erosion Resistance in Fine-Grained Soils with Newly Developed Test Equipment
Authors: Topçu Sadettin , Tosun Hasan
Published: October 2021

Dispersive soils cause great damage to hydrophilic earth structures and unprotected slope surfaces because of their high erosion sensitivity. In fine-grained soils, erosion resistance decreases with increased dispersibility. The dispersion mechanism of clays is controlled by the clay mineralogy and by the physicochemical repulsive forces in the clay–water system. The erosion resistance of dispersive soils can be determined by surface and internal erosion tests. In this study, the internal erosion resistance of soils was determined by using new test equipment that allowed the flow to pass through a hole when the dispersion mechanism in fine-grained soils was activated. The experiments for this study were performed under a single hydraulic head on two different natural dispersive soils with similar clay mineralogy. In this experimental system, both uniform and fully developed flow conditions were achieved. Time-dependent flow rates obtained from the experimental system can be used to determine hydraulic parameters, such as energy grade line, at very low error rates with the help of basic theorems of pipe hydraulics in theoretical hydraulic models, which were formed using a physical hydraulic model. Moreover, the erosion rates were quantitatively determined by using the continuity equation, and critical shear stresses were qualitatively compared for internal erosion developed by the dispersion mechanism. The sand/clay ratio determined the erosion resistance and behavior of the dispersive soils.
Perigenual and Subgenual Anterior Cingulate Afferents Converge on Common Pyramidal Cells in Amygdala Subregions of the Macaque
Authors: Kelly Emily A. , Thomas V. Kaye , Indraghanty Apoorva , Fudge Julie L.
Published: October 2021

The subgenual (sgACC) and perigenual (pgACC) anterior cingulate are important afferents of the amygdala, with different cytoarchitecture, connectivity, and function. The sgACC is associated with arousal mechanisms linked to salient cues, whereas the pgACC is engaged in conflict decision-making, including in social contexts. After placing same-size, small volume tracer injections into sgACC and pgACC of the same hemisphere in male macaques, we examined anterogradely labeled fiber distribution to understand how these different functional systems communicate in the main amygdala nuclei at both mesocopic and cellular levels. The sgACC has broad-based termination patterns. In contrast, the pgACC has a more restricted pattern, which was always nested in sgACC terminals. Terminal overlap occurred in subregions of the accessory basal and basal nuclei, which we termed “hotspots.” In triple-labeling confocal studies, the majority of randomly selected CaMKIIα-positive cells (putative amygdala glutamatergic neurons) in hotspots received dual contacts from the sgACC and pgACC. The ratio of dual contacts occurred over a surprisingly narrow range, suggesting a consistent, tight balance of afferent contacts on postsynaptic neurons. Large boutons, which are associated with greater synaptic strength, were ∼3 times more frequent on sgACC versus pgACC axon terminals in hotspots, consistent with a fast “driver” function. Together, the results reveal a nested interaction in which pgACC (“conflict/social monitoring”) terminals converge with the broader sgACC (“salience”) terminals at both the mesoscopic and cellular level. The presynaptic organization in hotspots suggests that shifts in arousal states can rapidly and flexibly influence decision-making functions in the amygdala.

SIGNIFICANCE STATEMENTThe subgenual (sgACC) and perigenual cingulate (pgACC) have distinct structural and functional characteristics and are important afferent modulators of the amygdala. The sgACC is critical for arousal, whereas the pgACC mediates conflict-monitoring, including in social contexts. Using dual tracer injections in the same monkey, we found that sgACC inputs broadly project in the main amygdala nuclei, whereas pgACC inputs were more restricted and nested in zones containing sgACC terminals (hotspots). The majority of CaMKIIα + (excitatory) amygdala neurons in hotspots received converging contacts, which were tightly balanced. pgACC and sgACC afferent streams are therefore highly interdependent in these specific amygdala subregions, permitting “internal arousal” states to rapidly shape responses of amygdala neurons involved in conflict and social monitoring networks.
Amazing Grace Keeps the Platters Spinning
Authors: De La Torre Monica , Marín Christine
Published: October 2021

In this photo essay, we center Chicana radio and television broadcasting trailblazer Graciela Gil Olivarez who, with a microphone in hand, amplified Mexicana and Chicana voices and stories across the Southwest from 1951 to the mid-1960s and again in the 1980s. Olivarez bridged her broadcasting work with an impressive career in government organizations that made her the highest-ranking Latina during President Jimmy Carter’s term. Through a series of photographs of Olivarez’s life and career trajectory, we mark the place of the first woman disc jockey in Phoenix, Arizona, and later owner of her own Spanish-language television network, KLUZ, in Albuquerque, New Mexico, as a key figure in Latina media histories. This photo essay mines the visual archive—photographs that span Olivarez’s early career in radio and television broadcasting and subsequent political work—in order to establish how Chicanas innovated media production to center their voices and narratives.
Sighting the Sound
Authors: Martínez-Cruz Paloma
Published: October 2021

Characterized by ambiguous sexual energy and resistance to male domination and objectification, the visual idiom of punk rock communicated feminist prospects through the performance of fashion. This essay interprets the creative agency of Alice Bag, Marina “Del Rey” Muhlfriedel, Trudie “Plunger” Arguelles-Barret, and Helen “Hellin Killer” Roessler as Latina and Hispanic sono-spatial artists in the early days of L.A.’s punk subculture. Situating the performance practices of Hispana (Iberian) women alongside the Latina (hemispheric Latin American) artists, L.A. punk is situated within a Spanish-American borderlands matrix of meaning, where non–Western European roots of women in punk gain coherence as a specifically bordered set of historical circumstances. By embodying musical performativity as creators of a relational theatre of musical experience, the study asserts that women punk fans redefined how alternative music was generated, circulated, and consumed.
Pero Like and mitú
Authors: Gutiérrez Arcelia
Published: October 2021

In 2016, Buzzfeed announced the creation of Pero Like, a Facebook page and YouTube channel that would “look at the myriad identities under the ‘Latinx umbrella,’” including “[B]laxicans in LA, Tejanos in Corpus Christi, Cubans in Miami (and their abuelitas), and everyone who’s been told they don’t ‘look Latina.’” Pero Like followed the footsteps of mitú, a new media multi-channel network created in 2012 to target younger, bicultural Latinx audiences who are avid internet users and overlooked by legacy media. This article analyzes how Latina millennial digital content creators negotiate, mediate, and contest Latinidad through social media entertainment. It focuses on four of the most popular Latina creators featured on mitú and Pero Like: Jenny Lorenzo, Kat Lazo, Julissa Calderon, and Maya Murillo. In doing so, the article explores how these creators articulate the politics of Latinx millenniality through a focus on cultural specificity, panethnicity, generational differences, language practices, race and racism, and beauty standards.
Tear And Serum Superoxide Dismutase And Catalase Activities In Hypertensive Retinopathy
Authors: Pavlovschi Ecaterina , Borovic Djina , Pantea Valeriana , Tagadiuc Olga
Published: October 2021

The objective was to determine the changes in SOD and catalase activity, markers of oxidative stress/antioxidant balance in serum and tear of patients with hypertensive retinopathy and to identify whether there was a correlation between their levels and HR degree of hypertensive retinopathy (HR). Material and Methods — 90 hypertensive patients were divided in three groups, according to the Keith-Wagener classification: GI-36, GII-35 and GIII-19. SOD was assessed using the Dubinina and Matyushin method and catalase according to Koroliuk, both in modification of Gudumac V. The results were presented by median and interquartile range. The groups were compared using Kruskal-Wallis and Mann-Whitney nonparametric tests, and the Spearman correlation coefficient was calculated (SPSS 23.0). Results — Showed a statistically significant difference of SOD in serum (p=0.035) and tear (p=0.027) between groups. SOD decreased from GI until GIII in serum (-8%, p=0.032) and tear (-16%, p=0.031). In addition, it showed a weak significant negative correlation with the HR degree both in serum (r=-0.246, p=0.019) and tear (r=-0.284, p=0.007), while the correlation attested between serum and tear SOD levels was significant moderate and positive (r=0.336, p=0.001). It was noted a significant catalase elevation in the tear (p=0.033). In serum it was not correlated with HR degree, while in tear showed a significant weak strength, positive correlation (r=0.261, p=0.013). No correlations were found between serum and tear catalase levels. Conclusion — A progressive significant decrease in SOD levels and a tendency to increase of catalase activity was identified as HR advanced both in serum and in tear. The enhancement in the severity of HR was correlated with decreased SOD activity in tear and serum and increased catalase level in tear.
Global DNA Methylation Of Brain Neurons In Acute Poisoning With Clozapine And Its Combination With Alcohol: An Experimental Study
Authors: Babkina Anastasiya S. , Khadzhiyeva Maryam B. , Ostrova Irina V. , Ryzhkov Ivan A. , Golubev Arkady M.
Published: October 2021

Background — Acute poisoning with atypical neuroleptic clozapine is characterized by rapid progression, high risk of death and severe neurological manifestations. Neurotoxic effects of this pharmaceutical drug have also been reported at therapeutic doses. The pathogenesis of brain damage in acute clozapine poisoning is not fully understood. Changes in DNA methylation level may play an important role in the mechanisms of drug neurotoxicity. The available data on the effect of clozapine on brain cell DNA provide a rationale for studying the epigenetic aspects of the pathogenesis of acute poisoning with this neuroleptic agent. The objective of our study was to evaluate the global DNA methylation level in rat brain neurons in acute poisoning with clozapine and its combination with ethanol. Material and methods — Clozapine – 150 mg/kg in 2.0 ml of normal saline solution, or clozapine – 150 mg/kg in 2.0 ml of 40% ethanol were administered via a gastric tube to adult male Wistar rats (n=21) under anesthesia with sevoflurane. In the control group, saline was administered via a gastric tube. Animals were euthanized four hours after drug administration. Autopsy was performed with the collection of brain samples for histochemical examination and determination of the DNA methylation level using the fluorometric method. To detect DNA in sections of paraffin-embedded tissue, we used the Feulgen staining. The TUNEL method was employed to detect DNA fragmentation. Results — An increase in the level of global DNA methylation in brain neurons was found in the clozapine and clozapine+ethanol groups. The average level of methylated DNA in the clozapine+ethanol group was higher than in the control group or clozapine group (2.56±0.31 vs. 1.35±0.1, p=0.007 and 1.70±0.33, p=0.044, respectively). An increase in the mean optical density of the cortical neuron nuclei was observed in the clozapine+ethanol group compared with the control group and clozapine group. DNA fragmentation was not detected in any experimental group. Conclusion — Acute poisoning with clozapine in combination with alcohol caused an increase in the global DNA methylation level in brain neurons, which may have played a significant role in the pathogenesis of acute clozapine poisoning and could be an important factor in the neurotoxicity of this medication.
Clinical Manifestations, Histopathological Changes And Quality Of Life In Patients With Advanced Knee Osteoarthritis Caused By Age, Trauma, Obesity And Their Combination
Authors: Korochina Kristina V. , Chernysheva Tatyana V. , Korochina Irina E.
Published: October 2021

Objective — to reveal and analyze clinical characteristics, knee joint histopathology, and quality of life in patients at late stages of knee osteoarthritis (OA) triggered by age, trauma, metabolic syndrome, or their combination. Material and methods — We studied 120 subjects with knee OA (sensu Altman R.D., 1991) of Kellgren-Lawrence Grades 3-4. They were distributed among 4 groups (30 participants in each) based on the presence of age-related, post-traumatic, metabolic, or combined phenotypes. Clinical examination of patients with pain and their functional status evaluation (via Visual Analogue Scale, WOMAC, Lequesne index), quality of life assessment (MOS SF-36 questionnaire), along with histopathological study of medial tibial plateau cartilage and synovial membrane, were caried out, followed by statistical data processing. Results — Age-related OA phenotype was characterized by the latest clinical onset [59.5 (54-68) years of age] with the largest average patient age [72.5 (63-77) years], moderate to severe pain and knee dysfunction [total WOMAC score of 160 (127-190) points and Lequesne index of 20 (8-21) points], severe degenerative cartilage lesions [8.5 (6-10) points sensu Mankin] with high-grade synovitis [5 (3-8) points sensu Krenn]. Post-traumatic OA phenotype was distinguished by the lowest pain, stiffness and knee functional limitations [total WOMAC score of 129 (100-166), Lequesne index of 15 (14-19)], the highest quality of life in patients [physical component summary of 34.1 (30.5-36.1) points, mental component summary of 40.4 (32.9-43.8) points] against the background of local severe cartilage lesions [8 (6-8) sensu Mankin] with reparative pattern and synovial fibrosis. For metabolic OA phenotype, the typical traits included female-biased sex ratio (87%), high prevalence of clinical synovitis (77%), severe pain and functional knee disorders [total WOMAC score of 188 (162-207) points, Lequesne index of 20 (19-23) points], the worst quality of life [physical component summary of 28.0 (24.3-31.9) points, mental component summary of 30.9 (26.9-35.9) points], vascular invasion of cartilage, and high-grade synovitis [4 (3-5) points sensu Krenn]. Combined OA phenotype was characterized by variable clinical and histopathological features. Conclusion — Comprehensive comparative clinical and morphological analysis of late-stage knee OA of various origin was completed, and age-related, post-traumatic, metabolic and combined OA phenotypes were studied. The methodological basis for differential approach to treating different categories of OA patients was developed.
Vinasse-Based Slow-Release Organo-Mineral Fertilizer with Chitosan-Bentonite Matrix
Authors: Qudus Nur , Kusumaningtyas Ratna Dewi , Syamrizal Zakky , Zakaria Zainul Akmar , Hartanto Dhoni
Published: October 2021

Controlling the release rate of the nitrogen-phosphorus-potassium (NPK) for the soil fertilized can enhance the fertilizer efficiency and reduce the drawback for the environmental. In this work, a novel slow-release organo-mineral fertilizer was produced from the vinasse, which was blended with the NPK and the chitosan-bentonite matrix. The NPK used as additional nutrients source and the chitosan-bentonite matrix was performed as a barrier to prevent the nitrogen, phosphorus, and potassium from a rapid dissolving. The NPK release rate was measured and analyzed after 3, 6, 9, and 12 days using the incubation method and leaching test. The most efficient release rate was obtained when a dry vinasse mixed with 9% NPK and 5% chitosan-bentonite matrix with the ratio of 8:2. The vinasse-based slow-release of organo-mineral fertilizer (SR-OMF) was compared to the vinasse organo-mineral fertilizer (OMF). The result indicated that the NPK release rate in the vinasse-based SR-OMF was lower compared to that in the vinasse OMF.
A single-centre retrospective analysis of cinacalcet therapy in primary hyperparathyroidism
Authors: Bell Daniel , Hale Julia , Go Cara , Challis Ben G , Das Tilak , Fish Brian , Casey Ruth T
Published: October 2021

Primary hyperparathyroidism (pHPT) is a common endocrine disorder that can be cured by parathyroidectomy; patients unsuitable for surgery can be treated with cinacalcet. Availability of surgery may be reduced during COVID-19, and cinacalcet can be used as bridging therapy. In this single-centre retrospective analysis, we investigated the utility and safety of cinacalcet in patients with pHPT receiving cinacalcet between March 2019 and July 2020, including pre-parathyroidectomy bridging. We reviewed and summarised the published literature. Cinacalcet dosages were adjusted by endocrinologists to achieve target calcium < 2.70 mmol/L. Eighty-six patients were identified, with the most achieving target calcium (79.1%) with a mean dose of 39.4 mg/day (±17.1 mg/day) for a median duration of 35 weeks (1–178 weeks). Calcium was normalised in a median time of 5 weeks. The majority of patients commenced cinacalcet of 30 mg/day (78 patients) with the remainder at 60 mg/day (8 patients). Forty-seven patients commencing lower dose cinacalcet (30 mg/day) achieved target calcium without requiring 60 mg/day. Baseline PTH was significantly higher in patients requiring higher doses of cinacalcet. 18.6% of patients reported adverse reactions and 4.7% discontinued cinacalcet. Patients treated with cinacalcet pre-parathyroidectomy required a higher dose and fewer achieved target calcium compared to medical treatment with cinacalcet alone. Post-operative calcium was similar to patients who were not given pre-parathyroidectomy cinacalcet. In summary, cinacalcet at an initial dose of 30 mg/day is safe and useful for achieving target calcium in patients with symptomatic or severe hypercalcaemia in pHPT, including those treated for pre-parathyroidectomy. We propose a PTH threshold of >30 pmol/L to initiate at a higher dose of 60 mg/day.
Eigenkapitalgenussrechte an Personengesellschaften als Alternative zu Streubesitzbeteiligungen an Kapitalgesellschaften
Authors: Kollruss Thomas
Published: October 2021

Im Rahmen einer quantitativ-ökonomischen Analyse untersucht die vorliegende Abhandlung die Beteiligungs- und Eigenkapitalfinanzierung bei Kapitalgesellschaften und leitet die steuerlichen und ökonomischen Implikationen ab. Insbesondere werden die Wirkungen der Streubesitzdividendenbesteuerung nach § 8b Abs. 4 KStG auf die Finanzierung von Kapitalgesellschaften diskutiert. Die ökonomischen Wirkungen der Dividendenbesteuerung auf die Beteiligungsfinanzierung bei Kapitalgesellschaften werden grundlegend beleuchtet. Als Lösungsansatz wird ein neues Instrument zur (Eigenkapital-)Finanzierung von Kapitalgesellschaften entwickelt und erörtert.
SENTIMENT ANALYSIS FOR SOCIAL MEDIA: A SURVEY
Authors: Phan Huyen Trang , Nguyen Ngoc Thanh , Hwang Dosam
Published: October 2021

With the rapid development of the Internet industry, an increasing number of social media platforms have been developed. These social media platforms have become the main channels for communication among most users. Opinions from social media platforms provide the most updated and inclusive information. Sentiments from opinions are a valuable data source for solving many issues. Therefore, sentiment analysis has developed into one of the most popular natural language processing fields. Hence, improving the performance of sentiment analysis methods or discovering new problems related to these methods is essential. In this context, we must be aware of the general information relevant to this area. This survey presents a summary of the necessary stages for building a complete model to be used in sentiment analysis. For each procedure, we list the popular techniques that have been widely used in recent years. In addition, discussions and comparisons related to these methods are provided. Additionally, we discuss the challenges and possible research directions for future research in this field.
Online learning for agricultural courses during COVID 19 : Students’ perceptions about its effectiveness
Authors: Mridula N. , Baby Smitha , Helen S.
Published: October 2021

The coronavirus pandemic has imperilled the teaching-learning process, forcing to adapt to online modes from kindergarten to the tertiary level, globally. In this setting, a study was conducted among randomly selected 120 undergraduate agricultural science students of Kerala Agricultural University regarding their experience based perceptions on the online learning effectiveness for their courses. As per the results, online learning was considered effective in terms of learning material supply, ease of taking exams, cost-effectiveness, doubt clearance and learning flexibility while it was considered ineffective with regard to team feeling and motivation. Connectivity issues, technical problems and lack of interaction have negatively affected the interest and the attention span of the students. The social science subjects (Agricultural Extension and Home Science) were recorded as easier to study online, though the conceptual clarity was negatively impacted in Agricultural Economics and Statistics. Plant Pathology, Agricultural Entomology and Plant Breeding were counted as hard to learn online. This study tries to call for change management in the online teaching-learning process in agricultural education system so that the prevailing uncertainties due to pandemic can be overcome and the teaching-learning activities can be resumed with quality and effectiveness.
Knowledge level of beneficiary and non-beneficiary red gram farmers
Authors: Prashanth S. , Aski S.G. , Gotyal S.H.
Published: October 2021

The research was conducted in Vijayapura district of Karnataka during the year 2019-20 with the sample size of 120 respondents. The findings revealed that, in case of beneficiary farmers about 40.00 per cent of red gram farmers were belonged to high level of knowledge. In case of nonbeneficiary farmers about 38.33 per cent of red gram farmers were belonged to medium level of knowledge. It is clear that, in case of beneficiary farmers about cent (100.00 %) per cent of the respondents had knowledge about improved red gram variety, recommended seed rate, recommended spacing, irrigation frequency, intercultivation, weeding, important pests, pest control, important diseases, harvesting and post-harvesting. In case of non-beneficiary farmers it is revealed that, cent (100.00 %) per cent of the respondents had knowledge about weeding and post-harvesting, 98.33 per cent of the red gram farmers had knowledge about inter cultivation, 90.00 per cent of the red gram farmers had knowledge about time of sowing, 86.67 per cent of the red gram farmers had knowledge about important diseases, 85.00 per cent of the red gram farmers had knowledge about disease control.
Contribuição para o uso de lodo de estação de tratamento de água in natura como agregado miúdo em concretos de cimento Portland: Avaliação da consistência, massa específica, porosidade, absorção, resistência à compressão e tração na compressão diametral
Authors: Meert Rúbia , Hastenpflug Daniel , Andrade Jairo José de Oliveira
Published: October 2021

RESUMO O tratamento de água para consumo gera uma grande quantidade de resíduos, o lodo de estação de tratamento de água (LETA). Normalmente, estes rejeitos são depositados em rios e em outros locais da natureza, gerando impactos ambientais tais como assoreamento, alteração da fauna e da flora local. Para colaborar com a mitigação desta prática, este estudo verificou a influência do uso do lodo de ETA, in natura, como substituição da areia natural em concretos de cimento Portland, nos teores de 0%, 5%, 10% e 20%, em massa. Para avaliar os efeitos causados pela incorporação do Lodo de ETA nas propriedades do concreto no estado fresco foram realizados os ensaios de abatimento do tronco de cone. Já no estado endurecido, foram conduzidos testes que observaram a porosidade aberta, a massa específica, a absorção de água, a resistência à compressão e à tração por compressão diametral. Verificou-se uma redução (de até 50%) da consistência do concreto à medida que se aumentava o teor de substituição. A porosidade aberta também aumentou conforme o incremento do teor de lodo de ETA. Devido a isto, ocorreu uma redução na massa específica dos traços e um incremento na absorção de água ao se aumentar a quantidade de resíduo. A resistência à compressão média, aos 7 dias, reduziu 31,45% quando se empregou 5% de lodo, 41,52% com 10% e 63,89% com 20%. Aos 28 dias, a resistência diminuiu 26,88% os menores teores e 59,78% para quantidades maiores. Já aos 91 dias, a capacidade portante foi 28,52% (para o uso de 5% de lodo), 40,33% (10% de resíduo) e 57,01% (20 de lodo de ETA) menores, respectivamente. A resistência à tração por compressão diametral, aos 28 dias de idade, seguiu a mesma tendência, ocorrendo uma redução de 29,06% em concretos com 5% de lodo e 65,98% com substituição de 20% de resíduo. De forma geral foi possível observar que o lodo de ETA tem grande potencial de aplicação à construção civil, apresentando um teor limite de aplicação de 10%, como agregado miúdo, sem gerar grandes prejuízos nas propriedades físicas e mecânicas.
Modeling tropospheric ozone and particulate matter in Tunis, Tunisia using generalized additive model
Authors: Hammouda Zouhour , Hedhili Zaier Leila , Blond Nadege
Published: October 2021

The main purpose of this paper is to analyze the sensitivity of tropospheric ozone and particulate matter concentrations to changes in local scale meteorology with the aid of meteorological variables (wind speed, wind direction, relative humidity, solar radiation and temperature) and intensity of traffic using hourly concentration of NOX, which are measured in three different locations in Tunis, (i.e. Gazela, Mannouba and Bab Aliwa). In order to quantify the impact of meteorological conditions and precursor concentrations on air pollution, a general model was developed where the logarithm of the hourly concentrations of O3 and PM10 were modeled as a sum of non-linear functions using the framework of Generalized Additive Models (GAMs). Partial effects of each predictor are presented. We obtain a good fit with R² = 85% for the response variable O3 at Bab Aliwa station. Results show the aggregate impact of meteorological variables in the models explained 29% of the variance in PM10 and 41% in O3. This indicates that local meteorological condition is an active driver of air quality in Tunis. The time variables (hour of the day, day of the week and month) also have an effect. This is especially true for the time variable “month” that contributes significantly to the description of the study area.
Age, growth and mortality of the European Seabass, (Dicentrarchus Labrax) in Bardawil lagoon, North Sinai, Egypt
Authors: Menna O El-Desoki , Younis M Younis , El-Dakar A Youssef , Salem M Ahmed , Kassem S Ahmed , Ahmed M Al-Beak
Published: October 2021

Age, growth, and mortality of European Seabass (Dicentrarchus labrax) were studied from a small-scaled fishery of Bardawil lagoon, (North Sinai, Egypt). 181 specimens (16.6 to 35 cm total Length and 39.8 to 367.2 g total weight). The relationship between length and weight was W = 0.0054L3.1428. Age was determined by otoliths and age groups I to IV years were observed. Growths in length and weight at the end of each year were calculated. The growth parameters of von Bertalanffy equation were calculated as (L∞ = 48.69 cm, K = 0.1677 yr -1 and t0 = -0.447 yr -1). Growth performance index was calculated (φ = 2.60 for length and 1.25 for weight). Mortality rates were 0.867 yr-1, 0.25 yr1and 0.617 yr-1 for total, natural and fishing mortality, respectively. The currently exploitation rate E = 0.712 yr-1 indicating that, the population of this species is being heavily exploited.
Chemical composition and in vitro digestibility of some range plants
Authors: Musa Ahmed Musa Tibin
Published: October 2021

This study was carried out to determine chemical composition and in vitro dry matter and organic matter digestibility of range plant species of the area. Samples were collected from range lands at full maturity stage, dried under shade and subjected to chemical analysis and dry matter and organic matter in vitro digestibility for Vigna sunhum, Andropogan gayanus, Pennisetum Pedicelatum, Shoenfeldia gracilis and Stylothanis flavicans were determined. The data was analyzed via analysis of variance and differences among means were determined using Least Significant Difference (LSD) test. The results showed that the legumes (Vigna sunhum and Stylothanis flavicans) were significantly higher (P≤0.01) in their crude protein content and the percentage of crude protein respectively was 13.4% and 10.00% while the grasses were significant (P≤0.05) higher in Crude Fibre (CF), ash, Acid Detergent Fibers (ADF) and Neutral Detergent Fibers (NDF). Crude fiber % values were 41.78, 43.37 and 46.07% for Pennisetum Pedicelatum, Andropogan gayanus and Shoenofeldia gracilis, respectively. The acid detergent values were 53.85, 47.74 and 53.39 for the three weeds. (P≤0.05), while the ratio of neutral detergent was significantly higher (P≤.05) in grasses than in the two legume species; 87.22, 82.35 and 88.99% for the three grasses respectively. Similarly higher in vitro dry matter and organic digestibility coefficients were obtained from legume species than grasses. The study concluded that, the studied grasses were higher in fiber content and lower in their protein content but, legumes grasses (Vigna sunhum, Pennisetum Pedicelatum and Stylothanis flavicans) had high nutritive value and in vitro digestibility which may provide ruminants with the needed protein and energy.
Te linee guida: la difficile applicazione tra clinica, scienza, giurisprudenza, sostenibilità economica ed organizzativa
Authors: Cosmi Franco
Published: October 2021

Introduzione. Le linee guida sono delle raccomandazioni con diversi livelli di evidenza scientifica messe a punto dagli esperti individuati dalle Autorità Regolatorie e dalle Società Professionali per consentire i migliori standard di intervento diagnostico e terapeutico al momento disponibili. Con la Legge 24/2017 in Italia sono diventate di osservanza giurisprudenziale, anche se a tutt’oggi mancano ancora le raccomandazioni ministeriali previste. Scopo. L’obiettivo dello studio è la valutazione nella pratica ambulatoriale cardiologica corrente dell’adesione alle linee guida della Società Europea di Cardiologia (ESC) riguardo i 3 principali fattori di rischio cardiovascolare: quelle sull’ipertensione del 2018, sulle dislipidemie e diabete mellito del 2019. Sono state valutate le criticità cliniche, amministrative ed organizzative che rendono difficoltosa la loro applicazione. Metodi e risultati. I target di valori pressori raccomandati dalle linee guida europee nei pazienti con sindrome coronarica cronica ipertesi comportano difficoltà decisionali soprattutto riguardanti la persistenza di valori di pressione sistolica elevata ≥ 140 mmHg con diastolica < 70 mmHg, ritenuti pericolosi dalle linee guida, valori di sistolica < 130 mmHg nelle persone di età ≥ 65 anni e in quelle con valori < 120 mmHg di età inferiore. Sempre in questi pazienti, con dislipidemia, la normativa vigente non prevede la rimborsabilità dei farmaci inibitori PCSK9 nei pazienti con livelli di LDL superiori all’obiettivo indicato di 55 mg/dl ma inferiore a 100 mg/dl. Nei pazienti diabetici a rischio molto elevato non è prevista la possibilità prescrittiva del cardiologo e dei medici di medicina generale degli ipoglicemizzanti appartenenti alle categorie degli SGLT2-i e GLP1-ar nonostante questi farmaci siano raccomandati in classe I A. Per le difficoltà organizzative riscontrate la prescrizione è limitata al 15-20% dei pazienti a rischio cardiovascolare molto elevato. Conclusioni. Le linee guida rappresentano le raccomandazioni per la migliore terapia a disposizione da parte della medicina ufficiale. Esse aiutano il medico a prendere la decisione terapeutica più congrua allo stato dell’arte. Problematiche di ordine clinico, amministrativo ed organizzativo rendono difficili gli adeguati percorsi diagnosticoterapeutici ed assistenziali necessari per la loro applicazione nella pratica clinica rendendo non ottimale il trattamento dei tre principali fattori di rischio cardiovascolare. L’inerzia terapeutica conseguente alla fatica burocratica potrebbe esporre il medico a problematiche medico-legali imputabili più a meccanismi di sistema che alla sua competenza professionale.
Teaching French Language Through Films: The Cultural Contents in French and Francophone Films
Authors: Tjahjani Joesana , Jinanto Damar
Published: October 2021

Foreign language teaching in the current globalization era needs to compete with technological development. This competition is related to the discovery of digital technology-based methods to motivate learners to provide more interesting cultural content in language classes. For teachers from different cultural backgrounds, authentic documents such as films are considered very effective in delivering cultural content. This research takes a French film, Intouchables, and a Canadian francophone film, Monsieur Lazhar, as a research corpus for their cultural content to be analyzed. The proper understanding of the two films' cultural content can inform a digital technology-based French-language teaching medium. To discover what strategies or formulas are used in teaching French with cultural-laden films as teaching media requires studying the films by dissecting the structure of the text. Examination of the structure of the films was based on the theory of Boggs and Petrie (2008), equipped with in-depth reading to find signs in the text by referring to Buckland (2004); and also the identification of cultural content using the cultural approach by Stern (1992). The construction of a teaching plan with a language teaching approach by Damen (1987) and Byram (1997) will be the last step. This research provides an academic outcome that is a film structural analysis to identify cultural content in the two films. The second outcome is a practical categorization of cultural content utilized as a language teaching material.
Photocatalytic treatment based on TiO2 for a coal mining drainage
Authors: Murcia Mesa Julie Joseane , Patiño Castillo Ceidy Geraldine , Rojas Sarmiento Hugo Alfonso , Navío Santos José Antonio , Hidalgo López María del Carmen , Angel Botero Alberto
Published: October 2021

The aim of the present work was to evaluate the effectiveness of a heterogeneous photocatalyst based on TiO2 in the treatment of coal mining drainage which contains a variety of heavy metals and high concentration sulfates and sulfides. The photocatalytic behavior of the commercial reference Sigma Aldrich and the different materials synthesized using the Sol-gel methodology with surface modifications using sulfation and fluorination processes were analyzed. To find a possible correlation between the physicochemical properties of photocatalysts and their behavior, a characterization was carried out using X-Ray Diffraction (XRD), X-Ray Fluorescence spectrometry (XRF), Fourier transform infrared spectroscopy (FT–IR), UV–Vis diffuse reflectance Spectra (UV-Vis DRS), N2 physisorption, X-ray photoelectron spectroscopy (XPS), and particle size analysis. Results indicated that the modification of the TiO₂ prepared in the laboratory using sulfation and fluorination allowed the successful control of the physicochemical properties of this oxide. However, commercial TiO2 showed the greatest effectiveness in removing metals such as: Fe, Cu, Cr, and As after a photocatalytic reaction for a maximum of 1 hour under continuous nitrogen flow and a light intensity of 120 W/m2.
Correlation analysis of interleukin-10 indicators and tumor necrosis factor-alpha as clinical indicators of rehabilitation treatment of postmastectomy lymphedema in patients after complex breast cancer treatment
Authors: Agranovich N. V. , Sivolapova Margarita S. , Kirsanova D. V. , Marchenko A. G. , Gulieva L. A. , Muskhadzhieva R. M. , Cнernomazov V. N. , Anopchenko A. S.
Published: October 2021

Background. Cellular immunity and cytotoxic agents are involved in the inflammatory process and tumor cell apoptosis resolution.Background. Cellular immunity and cytotoxic agents are involved in the inflammatory process and tumor cell apoptosis resolution. Endothelial cell apoptosis violation, imbalanced cytokines are considered as one of the contributory factors for postmastectomy lymphedema development.
Aim. To assess the correlation between the interleukin profile (interleukin-10 and tumor necrosis factor-alpha) and clinical indicators of postmastectomy lymphedema in the rehabilitation treatment course after complex breast cancer treatment
Materials and methods. The study involved 50 people aged 4065 years. The main group consisted of 40 females who underwent a rehabilitation treatment course for postmastectomy lymphedema. The control group consisted of 10 females with a verified breast cancer diagnosis who were preparing for surgical treatment. The statistical analysis determined the differences between the mean values of indicators using the Mann-Whitney U-test and the Wilcoxon T-test. Spearmans nonparametric correlation analysis was used to determine the relationship between the studied characteristics. Differences between indicators were considered statistically significant at p 0.05.
Results. The indices of the studied interleukins in the control group are significantly higher than that of the main group. Interleukin-10 remained unchanged in the course of restorative treatment, whereas tumor necrosis factor-alpha increased from 43.72 10 pg/l to 118.94 14.74 pg/l. After the course, a statistically significant correlation (p 0.05) was found between the levels of the studied interleukins. A positive trend was observed as a result of rehabilitation treatment of postmastectomy lymphedema: the average excess volume in patients of the main group decreased by 38.5%.
Conclusion. Evaluation of interleukin-10 and tumor necrosis factor-alpha in patients with postmastectomy lymphedema allows not only the restorative treatment results assessment and determination of the immune status parameter and damage degree of the vascular endothelium of a particular patient but also prognosis formation of malignant neoplasm development.
Indonesian Efl Learners’ Attitude And Perception On Taks-Based Language Teaching
Authors: Badrus Sholeh Muhammad , Salija Kisman , Sahril -
Published: October 2021

Task-based Language Teaching in Asia, especially Indonesia, was more popular in foreign language English teaching. The approach that focuses on the student is regarded to be more efficient than the traditional one. This study was undertaken so as to find out the attitude and perspective of learners regarding implementing language teaching based on tasks (TBLT). 96 learners of the Islamic Junior high school in Indonesia were randomly selected. In order to investigate participants' attitudes and perceptions a task based questionnaire has been designed. By employing the Likert Scale, data were evaluated quantitatively. The results of the study demonstrate that most EFL Indonesian learners have generally good attitudes and views concerning TBLT and so most of them like to join in TBLT English class. In other words, EFL learners are ready to adapt to a new methods of language learning because they are willing to apply TBLT successfully. In this study, some major issues highlighted by the results will be examined and some significant suggestions made by the results are discussed.
Negative Emotions Experienced by Polish English Teachers During COVID-19. A Qualitative Study Based on Diaries
Authors: Papaja Katarzyna
Published: October 2021

The aim of the article is to discuss the research results of the study conducted on English teachers’ negative emotions experienced during COVID-19. In order to collect the data, 30 English teachers from secondary schools were asked to keep a diary for one semester and describe situations that aroused feelings of anxiety, anger, and loneliness. The study was of a qualitative nature, and it showed that most of the emotions that the English teachers experienced were associated with the lack of support from the government and their colleagues, and also with the uncertainty about the future.
Public diplomacy in selected conceptual documents of the Russian Federation, in the period 1991-2016
Authors: Janczuk Artur
Published: October 2021

2020 is the year of publication of a new military doctrine of the Russian Federation. The document will, undoubtedly, be received as an interesting object of analysis, expected to show not only direct intentions, but also the hinking patterns representative for the Russian political elites. It is, therefore, advisable to process the history of public diplomacy – the leading tool of building soft power – a long-standing component of Russian Federation’s capability, which due to the composition of determinants typical for the late-Westphalian international order gained an unprecedented level of meaning (or even can be seen as a leading factor). For these reasons, the author – after adopting a working definition – attempts to retrace the direct and indirect (implied) instances of including public diplomacy into the most important strategic documents and legal acts, issued by Russia in the years 1991-2016. The analysis shows the evolution of Russia’s political elites’ approach to all of the dimensions of public diplomacy (shift from superficial westernisation and a liberal discourse on the international order, through demonstrations of assertiveness, to a narrative adopotion of the role of one of the poles of the new international order), and provides insight into the composition of the political, social end economic determinants behind the transition. Also discussed are the shifts within the specifics of the methods of public diplomacy – such as the perception of the role of diaspora, or the link between image, economic diplomacy and economic development. These changes are presented on the background of the state of the international system, and the analysis is an addition to the extensive literature on the Russian Federation’s informational influence.
Transformation in nursing education in India: Current issues
Authors: Garadi Shweta , Sharma Rakesh , Jelly Prasuna , Rani Ruchika
Published: October 2021

This paper is aimed to understand the current issues in nursing education in India. Nursing education has gained great demand around the globe in the current scenario to call forth efficient nurse leaders and nurse executives. Nursing knowledge gained by a student is equally proportionate to competencies they develop in the future. Advancing skills, adapting to the changed curricula, implementing competitive teaching-learning methods in all nursing programs are the need of the hour now.
A study to assess the knowledge and practices related to menstruation and menstrual hygiene among adolescent girls of selected school of District Ambala, Haryana
Authors: Kalyan Geetanjli , Walia Amandeep Kaur , Kaur Manpreet , Kaler Amandeep , Kaur Bajwa Amandeep , Kaur Amanpreet , Kaur Sandhu Amanjot , Chauhan Ambika , Franklin Andrew , Sharma Ankita
Published: October 2021

:  Menarche, among Adolescence girls, signifies the adaptation to womanhood as it is associated with pubertal changes and beginning of the capacity to reproduce. This is a period of gonadal development and growth spurt. Menstrual hygiene is crucial to healthy reproductive system and in return to good physical health and wellbeing. Therefore, enhanced awareness regarding menstruation and related hygiene, right from adolescence may escalate safe practices that are helpful in alleviating the distress of millions of women.

: To assess the knowledge and practices related to menstruation and menstrual hygiene among adolescent girls of selected schools of District Ambala, Haryana

A descriptive cross sectional study was conducted in selected schools of Mullana and Barara District Ambala, Haryana.

Total enumeration sampling technique was used to enroll 192 adolescent girls from class 9 to class 12 from selected schools after obtaining written informed consent from parents and verbal consent from girls. Ethical clearance was obtained from Institute Ethics committee. Doubts of the participants were cleared after data collection.

Among 192 girls, nearly half girls were aware of menstrual hygiene and reported use of sanitary nepkins and 40.1% girls were aware of the symptoms of poor menstrual hygiene. .

There is a need to implement an education program for adolescent girls on menstruation and menstrual hygiene to ensure healthy menstrual practices.