bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALYSIS OF THE FINANCIAL SITUATION AND THE IDENTIFICATION OF THREATS AS A MEANS OF FORECASTING THE PROBABILITY OF BANKRUPTCY OF AN INDUSTRIAL ENTERPRISE
Authors: T. O. MELIKHOVA
Published: July 2023

The purpose. The work is devoted to the analysis of the financial condition and the identification of threats as a means of predicting the probability of bankruptcy an industrial enterprise. The methodology. To solve the tasks it`s proposed to apply the methodology for predicting the probability of bankruptcy of an enterprise. The results. The paper considers the existing indicators of financial analysis of an industrial enterprise which are often used in practice. They have certain drawbacks since it`s difficult to choose a convenient methodology for conducting financial analysis through their diversity, besides, there are methods that do not take into account industry differences. Some methods are based on foreign methods and don`t take into account the peculiarities of domestic industrial enterprises. The uses of some standard values are not sufficiently reasonable. In the selection of indicators, there is certain subjectivity and the importance of their influence on the overall financial condition of the company.The article analyzes the financial condition of ZTMK, LLC, in order to identify threats to the likelihood of bankruptcy for 2013-2017. The analysis was conducted in: liquidity, solvency, business activity, profitability. The analysis of the probability of bankruptcy of ZTMK LLC was carried out according to the models of Altman, Springate, Taffler and Tishou, Saifulin-Kadykov,Lys, Konan and Golder, Beaver for 2013-2017.Scientific novelty. For assessing the financial condition of an industrial enterprise it was proposed to use a few methods: coefficient method, integrated method, integral method, break-even method, investment method, the method of the assessment of the financial stability of the enterprise. In the assessing of probability bankruptcy of an enterprise and its creditworthiness, it is recommended to calculate the following main sets of indicators: rentability and profitability, liquidity, financial sustainability, turnover.Practical significance. Among the presented models of the study of the probability of bankruptcy, there is no methodology with reliable diagnostic results since when using these methods to predict the probability of bankruptcy, contradictory results were obtained about the threat of bankruptcy.
Intraperitoneal injection of cell-engineered pancreas in rats with experimental type i diabetes (preliminary results)
Authors: Ponomareva A. S. , Baranova N. V. , Nikolskaya A. O. , Kirsanova L. A. , Onishchenko N. A. , Gonikova Z. Z. , Bubentsova G. N. , Volkova Е. A. , Basok Yu. B. , Sevastianov V. I.
Published: July 2023

Creation of a bioartificial pancreas, including a cell-engineered construct (CEC) formed from pancreatic islets (islets of Langerhans) and a biocompatible matrix mimicking the native microenvironment of pancreatic tissue, is one of the approaches to the treatment of type 1 diabetes mellitus (T1D).

Objective: to conduct preliminary in vivo studies of the functional efficacy of intraperitoneal injection of a cell-engineered pancreatic endocrine construct and a suspension of rat pancreatic islets in an experimental T1D model.

Materials and methods. Tissue-specific scaffold was obtained by decellularization of human pancreatic fragments. The viability and functional activity of rat islets isolated with collagenase were determined. Experimental T1D was modeled by intraperitoneal injection of low-dose streptozotocin and incomplete Freund’s adjuvant into rats. The rats were intraperitoneally injected twice with pancreatic CEC (n = 2) or islet suspension (n = 1). Glucose levels in the blood and urine of the rats were assessed. Histological examination of organs (pancreas and kidneys) of the experimental animals was carried out.

Results. After the first injection, blood glucose levels gradually decreased in all animals by more than 47% of the initial values; by follow-up day 24, the glucose level rose to the initial hyperglycemic values. After repeated administration, a 63.4% decrease in glycemic level was observed in the rats with pancreatic CEC and a 47.5% decrease in the one with islet suspension. At week 5 of the experiment, blood glucose levels gradually increased in all animals. At the same time, the glycemic index of the rat with injected pancreatic CEC was 62% lower than the glycemic index of the rat with injected islets.

Conclusion. Allogeneic pancreatic islets in pancreatic CEC increase the duration of stable glycemic level in T1D rats.
Galectin-3 in solid organ recipients: role in graft pathology and prospects for use
Authors: Velikiy D. A. , Osoblivaya M. A. , Shevchenko O. P.
Published: July 2023

Galectin-3 (Gal-3) is an important regulator of cell adhesion, migration, proliferation, differentiation and apoptosis under pathophysiological conditions. It plays a crucial role in diseases associated with chronic inflammation and fibrosis. In recent years, there have been reports indicating changes in serum Gal-3 levels in solid organ transplant recipients in the verification of kidney, liver, heart and lung transplant pathologies. Studies on Gal-3 levels and dynamics in solid organ recipients may serve to assess graft conditions using new minimally invasive methods and to identify therapeutic targets for personalized therapy. The first clinical trial data on Gal-3 pharmacological inhibition are emerging. This review summarizes the current understanding of the role of Gal-3 in transplant pathology and the prospects for its use as a diagnostic marker and therapeutic target in solid organ recipients.
Choice Of treatment method for symptomatic Bladder outlet obstruction in patients with benign prostatic hyperplasia after kidney transplantation
Authors: Popov S. V. , Huseynov R. G. , Saydulaev D. A. , Sadovnikov S. V. , Kisil Yu. V. , Sivak K. V. , Bunenkov N. S. , Perepelitsa V. V. , Ulitina A. S. , Lelyavina T. A.
Published: July 2023

St. Petersburg, Russian Federation The paper presents a comparative assessment of different methods of treating symptomatic bladder outlet obstruction (BOO) in patients with benign prostatic hyperplasia (BPH) who underwent kidney transplantation (KT).
Pericardial window as a surgical method for preventing significant postoperative pericardial effusion
Authors: Kiryakov K. S. , Zakiryanov A. R. , Khalilulin T. A. , Zakharevich N. Y. , Pozdnyakov O. A. , Goltz А. M. , Ivanov D. S. , Sukhachev A. A. , Zakharevich V. M.
Published: July 2023

Postoperative pericardial effusion (PPE) represents a very common complication in cardiac surgery. Accumulation of a significant amount of free fluid in the pericardial cavity is a multifactorial process. Identifying the cause is not always possible. This complication occurs more frequently in patients after heart transplantation than in patients who underwent reconstructive cardiac surgery. Having hemodynamically significant effusion requires surgical evacuation of fluid from the pericardial cavity. This can affect the postoperative period and increase the length of stay at the hospital. For this reason, developing and ensuring widespread use of methods for prevention of this complication are urgent and relevant tasks.
Fertilization strategies to reduce the formation of stenospermocarpic mango fruits in the semiarid region
Authors: Cavalcante Ítalo Herbert Lucena , Carvalho Camila Israela Freire Silva , Lima Augusto Miguel Nascimento , Silva Roberto Lustosa , Silva Kátia Araújo da , Rodrigues Marcos Sales
Published: July 2023

Abstract The mango cultivation has shown considerable losses, due to the intense occurrence of physiological disorders in its fruits, and stenospermocarpy is the main disorder under tropical semiarid conditions. So, the experiment was carried out to evaluate the potential loss of yield of mango cv. Palmer by stenospermocarpy, its relation with the nutritional state of the plant and yield as a function of fertilization strategies. The study was conducted in two experimental areas in the Brazilian semiarid. There is evidence that the leaf contents of phosphorus (P), iron (Fe) and zinc (Zn) influenced the development of stenospermocarpy fruits, associated with high temperature and low relative humidity in the flowering period of the crop. The incidence of fruits affected by stenospermocarpy reaches 90%, with an estimated yield loss of 28.81 Mg ha-1 for the mango cv. Palmer.
VIS-NIR portable espectrometer for non-destructive assessment of maturity and quality of ‘Gala’ apples
Authors: Bellotto Jádina Cristina Vaz Moraes , Coser William , Amarante Cassandro Vidal Talamini do , Steffens Cristiano André , Argenta Luiz Carlos , Freitas Sérgio Tonetto de
Published: July 2023

Abstract Visible and near infrared (VIS-NIR) spectroscopy is a non-destructive, fast, practical and reliable technique to determine maturity and quality attributes in apple fruit. However, the effects of cultivar and growing conditions on the predictive performance of the equipment must be determined before its commercial application in the apple industry. This study was carried out to evaluate the efficiency of a VIS-NIR portable spectrometer for fast and non-destructive determination of quality attributes in apples of the ‘Gala’ group (‘Maxi Gala’, ‘Royal Gala’, ‘Imperial Gala’ and ‘Galaxy’) harvested in three commercial orchards (corresponding to the production sites: Vacaria, Fraiburgo and São Joaquim) in Southern Brazil. At the commercial harvest and after three months of cold storage (1.5 ± 0.3 ºC and relative humidity of 92 ± 2%), fruit were assessed in terms of spectral data in the wavelength range between 310 and 1100 nm with a VIS-NIR portable spectrometer. After collecting the spectral data, fruit were submitted to physicochemical analysis of dry matter (DM), soluble solids content (SSC), flesh firmness and texture. The calibration models were developed using three sets of spectral and physicochemical data: (1) without separating by cultivar and orchard; (2): separating by cultivar, regardless of orchard; (3): separating by cultivar and by orchard. The calibration models were obtained by the partial least squares (PLS) regression technique. The accuracy of the calibration models for each dataset was evaluated in the validation step considering the values of the relative root mean square error of cross-validation (RMSECVr = 10%). Models developed for each cultivar in each orchard (location) were more accurate and efficient to assess DM, SSC and flesh firmness, compared to the models developed for each cultivar, regardless of orchard, or without separating by cultivar and by orchard. Therefore, VIS-NIR spectrometer is a promising tool for the rapid and non-destructive analysis of quality attributes in ‘Gala’ apples. However, the equipment must be calibrated for each cultivar (‘Maxi Gala’, ‘Royal Gala’, ‘Imperial Gala’ and ‘Galaxy’) and growing condition (orchard) in order to obtain more precise analyses of DM, SSC and flesh firmness in the fruit.
Do Bolsa Família ao Auxílio Brasil: desafios e alcances a partir de uma pesquisa avaliativa baseada na teoria do programa
Authors: Costa Delaine Martins , Magalhães Rosana , Cardoso Maria Lúcia de Macedo
Published: July 2023

Resumo: A recente pandemia de COVID-19 levou muitos países a adotarem políticas emergenciais de transferência de renda como forma de conter a crise econômica e humanitária. Tais iniciativas foram desenvolvidas em um contexto de agudização das desigualdades de gênero, raça, etnia e classe em decorrência de medidas de isolamento físico e social. O artigo analisa, a partir de um estudo exploratório e da chamada avaliação baseada na teoria do programa, as premissas teóricas dos programas Bolsa Família (2003), Auxílio Emergencial (2020) e Auxílio Brasil (2021) e suas respectivas dinâmicas de implementação. Na medida em que os programas de transferência de renda ocupam lugar central na agenda pública contemporânea, conclui-se que a avaliação de limites e avanços, tanto em sua concepção teórica como em relação aos mecanismos disparados em cada contexto, contribui para revelar evidências sobre sua efetividade no enfrentamento das desigualdades duráveis e daquelas que surgem em cenários de emergência sanitária.
LAPAROSCOPIC BARIATRIC SURGERY IN ADOLESCENTS: EARLY AND FIVE- YEAR CLINICAL AND LABORATORY ASSESSMENT
Authors: Gottardi Lorena , Tinoco Augusto , Alberti Luiz Ronaldo
Published: July 2023

ABSTRACT BACKGROUND: Obesity has reached epidemic proportions among adolescents. Methods, such as bariatric surgery, have become the most effective treatment for patients with classes III and IV obesity. AIM: To evaluate weight loss, comorbidity remission, and long-term results of bariatric surgery in adolescents. METHODS: Study with adolescent patients undergoing bariatric surgery, evaluating laboratory tests, comorbidities, and the percentage of excess weight loss in the preoperative period and at one, two, and five years postoperatively. RESULTS: A total of 65 patients who met the inclusion criteria, with a mean age of 18.6 years, were included in the analysis. In the preoperative period, 30.8% of hypercholesterolemia, 23.1% of systemic arterial hypertension, and 18.4% of type 2 diabetes were recorded, with remission of these percentages occurring in 60, 66.7 and 83.4%, respectively. The mean percentage of excess weight loss was 63.48% after one year of surgery, 64.75% after two years, and 57.28% after five years. The mean preoperative total cholesterol level was 180.26 mg/dL, and after one, two, and five years, it was 156.89 mg/dL, 161.39 mg/dL, and 150.97 mg/dL, respectively. The initial mean of low-density lipoprotein was 102.19mg/dL and after five years the mean value reduced to 81.81 mg/dL. The mean preoperative glycemia was 85.08 mg/dL and reduced to 79.13 mg/dL after one year, and to 76.19 mg/dL after five years. CONCLUSIONS: Bariatric surgery is safe and effective in adolescents, with low morbidity, resulting in a loss of excess weight and long-term stability, improving laboratory tests, and leading to remission of comorbidities, such as diabetes mellitus, hypercholesterolemia, and systemic arterial hypertension.
LIVER TRANSPLANT FOR METASTATIC NEUROENDOCRINE TUMORS: A SINGLE-CENTER REPORT
Authors: Sampaio Raquel Lima , Coelho Gustavo Rego , Quidute Ana Rosa Pinto , Rocha Filho Duilio Reis da , Soares Carlos Eduardo Lopes , Garcia José Huygens Parente
Published: July 2023

ABSTRACT BACKGROUND: Neuroendocrine tumors are rare neoplasms of uncertain biological behavior. The liver is one of the most common sites of metastases, occurring in 50% of patients with metastatic disease. AIMS: To analyze a clinical series in liver transplant of patients with neuroendocrine tumors metastases. METHODS: A retrospective descriptive study, based on the review of medical records of patients undergoing liver transplants due to neuroendocrine tumor metastases in a single center in northeast Brazil, over a period of 20 years (January 2001 to December 2021). RESULTS: During the analyzed period, 2,000 liver transplants were performed, of which 11 were indicated for liver metastases caused by neuroendocrine tumors. The mean age at diagnosis was 45.09±14.36 years (26–66 years) and 72.7% of cases were females. The most common primary tumor site was in the gastrointestinal tract in 64% of cases. Even after detailed investigation, three patients had no primary tumor site identified (27%). Overall survival after transplantation at one month was 90%, at one year was 70%, and five year, 45.4%. Disease-free survival rate was 72.7% at one year and 36.3% at five years. CONCLUSIONS: Liver transplantation is a treatment modality with good overall survival and disease-free survival results in selected patients with unresectable liver metastases from neuroendocrine tumors. However, a rigorous selection of patients is necessary to obtain better results and the ideal time for transplant indication is still a controversial topic in the literature.
Epidemiology and severity of traumatic dental injuries in permanent teeth: A 20-year retrospective study
Authors: Vieira Walbert A. , Pereira Andrea C. , Lazzari Jaqueline , Pecorari Vanessa G.A. , Gomes Brenda P.F.A. , Almeida José Flávio A. de , Ferraz Caio C. R. , Santos Eduardo C. A. , Vargas-Neto Júlio , de-Jesus-Soares Adriana
Published: July 2023

Abstract This study aimed to assess the traumatic dental injuries (TDIs) in permanent dentition among patients who attended at the outpatient clinic of a Brazilian dental school, during the last 20 years, and to investigate factors associated with the severity of these injuries. Clinical records of patients who attended a specialized center for dental trauma care in Brazil presenting at least one TDI in a permanent tooth, between the years 2000 and 2019, were reviewed. The data recorded were sex, age, affected arch, etiology, number, and type of the teeth affected, and classification and severity of the TDIs. The diagnosis and classification of the TDIs were based on the guidelines of the International Association of Dental Traumatology (IADT). The severity of each patient's injuries was defined as mild, moderate, or severe. Descriptive statistics, chi-square and multinomial regression analyses were used to evaluate the results. The significance level was set at 5%. A total of 837 clinical records were included, totaling 2357 teeth. Males were more prevalent than females. The patients' age ranged from 5 to 71 years. The most common traumas were avulsion (n=512) and uncomplicated enamel-dentin fracture (n=488). Univariate analyses showed that there was a statistically significant association between age group (p=0.004), etiology (p=0.000) and number of teeth affected (p=0.000) with severity of dental trauma. In conclusion, TDIs that occurred in Piracicaba and region are epidemiologically similar to those found worldwide, and that more severe injuries are related to age range, etiology and number of teeth affected.
Prevalence of lectures about dental esthetics and female speakers in three Brazilian conferences
Authors: Conceição Karen Larissa Oliveira , Soares Karla Danielly Alves , Bragança Rafaella Mariana de , Correa Marcos Britto , Moraes Rafael Ratto , Faria-e-Silva André Luis
Published: July 2023

Abstract This study analyzed the prevalence of lectures involving esthetics in the scientific program of Brazilian dental conferences and the gender distribution of speakers. All lectures presented in three dental conferences (Bahia, São Paulo, and Goiás states) held from 2016 to 2020 were evaluated. Three investigators individually divided the lectures according to the specialties recognized by the Brazilian Federal Council of Dentistry (FCD) based on their titles. The lectures were also classified as involving or not esthetics, and the speaker`s gender was recorded. Descriptive statistical analyses were performed, and Chi-square tests assessed possible associations between factors. The words most cited in the titles of the lectures were “esthetic” (13.6%), “dentistry” (9.9%), and “treatment” (8.1%). Oral diseases were barely mentioned in the titles (up to 1.3%). The highest number of lectures was observed for the specialty of Restorative Dentistry (22.3%), followed by Prosthodontics (18.5%). Approximately one-third of lectures involved some aesthetic aspect, but this percentage ranged from 71.9 to 78.6% for the two specialties with more lectures. Regarding the speaker`s gender, the inequity was higher for lectures involving esthetics (81.6% of males) than for topics unrelated to esthetics (66.7%). More male speakers than females were observed for all specialties. The highest gender gap was observed for Pediatric Dentistry with 62.4% male speakers, although only 10.6% of FCD registered specialists were men. In conclusion, the Brazilian dental conferences analyzed seemed to favor offering lectures dealing with esthetic topics and male speakers.
Evaluation of IL-4, MIP-1α, and MMP-9 gene expression levels in peri-implant tissues in peri-implantitis
Authors: Giro Gabriela , Taira Jorge , Andriani Fernando , Watinaga Sidney , Bastos Marta Ferreira , Shibli Jamil Awad
Published: July 2023

Abstract This case-control study evaluated the gene expression levels of interleukin (IL)-4, macrophage inflammatory protein type 1 alpha (MIP-1α), and metalloproteinase (MMP)-9, factors involved in the formation of giant cells in healthy peri-implant tissue and peri-implantitis. Thirty-five subjects (15 healthy and 20 with peri-implantitis), who met the inclusion and exclusion criteria, were included in this study. The peri-implant tissue biopsies were subjected to total RNA extraction, DNAse treatment, and cDNA synthesis. Subsequently, the reaction of real-time PCR was performed to evaluate the gene expression levels of IL-4, MIP-1α, and MMP-9 concerning the reference gene. IL-4 gene expression showed higher (18-fold) values in the Peri-Implantitis Group of Patients when compared with the Healthy (Control) Group (p<0.0001). Although MIP- 1α and MMP-9 gene expression levels were higher in diseased implants, they showed no significant differences (p=0.06 and p=0.2337), respectively. Within the limitations of this study, the results showed that in tissues affected by peri-implantitis, only levels of Il-4 were increased when compared with tissues in the control group.
Effect of sodium/calcium hypochlorite on adhesion and adaptation of fiber posts luted with a dual resin cement
Authors: Pauletto Guilherme , Carlotto Israel Bangel , Rosa Lucas Saldanha Da , Pereira Gabriel Kalil Rocha , Bier Carlos Alexandre Souza
Published: July 2023

Abstract This study aimed to evaluate the effect of different concentrations of sodium hypochlorite (NaOCl) and calcium hypochlorite [Ca(OCl)2] on the bond strength and adaptation of glass fiber posts luted with a dual-curing resin cement. Fifty decoronated premolars were sectioned 14 mm from the apex and endodontically treated. The root canal filling was partially removed. The specimens were divided into 5 groups (n=10) according to the irrigant for post space irrigation: 0.9% sodium chloride (NaCl), (control); 2.5% NaOCl; 5.25% NaOCl; 2.5% Ca(OCl)2; and 5.25% Ca(OCl)2. For each group, irrigation was performed with 5 ml of solution. Afterward, the posts were luted with a dual-curing resin cement. One slice from each third was obtained and submitted to the push-out test and failure modes analysis. An additional slice from the middle third was submitted to confocal images for analysis of adaptation failures (gaps). Two-way ANOVA, Tukey’s post-hoc, Kruskal-Wallis with Bonferroni adjusted, and chi-square tests, analyzed data. The group treated with 5.25% NaOCl showed lower bond strength values and generated more cohesive failures compared to the control (p < 0.05). Bond strength decreased from coronal to apical in the post space (p < 0.001). The groups treated with NaOCl had the highest percentages of gaps compared to the control (p < 0.05). Regardless of concentration, Ca(OCl)2 did not influence the bond strength and the occurrence of gaps (P > 0.05). Ca(OCl)2 is a good option for irrigating the post space before luting a fiber post with a dual-curing resin cement.
Morphometric analysis and roosting ecology of bat species Pteropus Medius in Mansehra, Khyber Pakhtunkhwa, Pakistan
Authors: Rehbar B. , Bilal M. , Hassan H. U. , Gabol K. , Khan M. F. , Nadeem K. , Ullah S. , Taj M. , Khan F.A. , Abbas M. , Ibrahim M. , Haq I. U. , Ahmad A. , Ríos-Escalante P. R.
Published: July 2023

Abstract Morphometric measurement and roosting ecology of Pteropus medius were aimed to find out in Mansehra district of KP, Pakistan. Total 3149 numbers of bats were found in eight biological spots visited; Baffa Doraha, Darband, Dadar, Jallu, Hazara University, Garhi Habibullah Chattar Plain and Jabori, in total 299 numbers of different species of trees including; Morus alba, Pinus raxburghi, Eucalyptus camaldulensis, Morus nigra, Grevillea robusta, Brousonetia papyrifera,Platanus orientalis, Ailanthus altissima, Hevea brasiliensis and Populus nigra. Morphometric features were measured and found vary according to sex of the bats. The average wing span, wing`s length from tip of wing to neck, from thumb to tip of wing and the body`s length from head and claws were recorded to be 102.98 cm, 49.07cm, 28.7 cm and 22.78 cm respectively in males while 93.67 cm, 44.83cm, 24.78cm and 22.78 cm respectively in female bats. Mean circumference of the body including wings and without wing were measured as 22.78 cm and 17.29 cm in males and that of female were 20.07 cm and 16.9 cm. Average length of thumb 3.64 cm, ear`s length 3.1 cm, snout 5.62cm, eye length were 1.07 cm for both sexes and length between the feet in extended position were16.3 cm. Generally different measurement of males bodies were found to be greater than female such as mean body surface area, mass, volume and pressure were found to be 2691.79 cm2, 855.7gm,1236.4 ml and 295.77 dyne/ c m 3for male and 2576.46 cm2, 852.71gm,1207 ml and 290.2 dyne/ c m 3 respectively for female. While weight and density for both males and females bats were same with mean of 8.59 newton and 0.701 g/m3. Findings of current reports can add valued information in literature about bats, which can be used for species identification and conservation.
Chemical constituents and antifungal potential of Attalea geraensis Barb. Rodr. (Arecaceae) palm leaves, a species native to the Cerrado of Brazil
Authors: Silva B. C. F. L. , Matias R. , Oliveira A. K. M. , Corrêa B. O. , Pinto L. S. , Costa R. F. , Heredia-Vieira S. C.
Published: July 2023

Abstract Fungal diseases, especially those that affect the root systems of plants, caused by Rhizoctonia and Macrophomina are limiting factors for achieving high crop yields. Alternatives to controlling fungi with chemical products drive the search for new options for bioactive compounds from plants. Attalea geraensis, a palm tree from the Brazilian Cerrado, is rich in flavonoids with antifungal actions. The objective of this work is to identify the chemical classes present in the ethanolic extract of green leaves of A. geraensis and determine the antifungal potential of the extract against isolates of Macrophomina phaseolina (Tassi) Goid. and Rhizoctonia solani JG Kühn. Phytochemical prospection, flavonoid dereplication, and antifungal activity were carried out of the ethanolic extract of the green leaves of A. geraensis harvested in the Cerrado area of Brazil. Steroids, triterpenes, saponins, and anthraquinones are described here for the first time for the leaves of A. geraensis. The flavonoids quercetin, isorhamnetin, 3,7-dimethylquercetin, quercetin 3-galactoside, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4H-chromen-4-one, rhamnazin 3-galactoside, keioside, and rhamnazin 3-rutinoside were identified. Of these, only quercetin and isorhamnetin had already been identified in the leaves of A. geraensis. The results show a fungistatic potential for the species. The diversity of flavonoids present in the leaves of A. geraensis may be the result of a synergistic action between fungus and plant or there could be an antagonistic effect between flavonoids and the other identified chemical classes.
Influence of atherosclerosis risk factors on the anatomical distribution of peripheral arterial disease in patients with chronic limb-threatening ischemia: a cross-sectional study
Authors: Santos Vanessa Prado dos , Cerutti Camila Izabel , Alencar Marcelo José Carlos , Queiroz André Brito , Ferreira Lucas de Mello , Fidelis Cícero , Araújo Filho José Siqueira de , Alves Carlos Alberto Silveira
Published: July 2023

Abstract Background Atherosclerosis risk factors can have different impacts on cardiovascular diseases and on the anatomical distribution of Peripheral Arterial Disease (PAD). Objectives To study the influence of atherosclerosis risk factors on the anatomical distribution of PAD in patients with chronic limb-threatening ischemia (CLTI). Methods We performed an observational, cross-sectional, and analytical study that included 476 hospitalized patients with CLTI due to PAD. We compared the presence of atherosclerosis risk factors (age, gender, diabetes mellitus, smoking, and hypertension) in patients with PAD involving three different anatomic areas (aortoiliac, femoropopliteal, and infrapopliteal). Multivariate analysis was performed to identify associations between atherosclerosis risk factors and PAD distribution. Results The mean age of the 476 patients was 69 years, 249 (52%) were men, and 273 (57%) had diabetes. Seventy-four percent (353) had minor tissue loss. Multivariate analysis identified three risk factors associated with PAD anatomical distribution (gender, smoking, and DM). Women had a 2.7 (CI: 1.75-4.26) times greater chance of having femoropopliteal disease. Smokers had a 3.6-fold (CI: 1.54-8.30) greater risk of aortoiliac disease. Diabetic patients were 1.8 (CI: 1.04-3.19) times more likely to have isolated infrapopliteal occlusive disease. Conclusions The study showed that gender, DM, and smoking impact on the anatomical distribution of PAD in patients with CLTI. Diabetic patients were more likely to have only infrapopliteal disease, women had a greater risk of femoropopliteal PAD, and smokers had a greater risk of aortoiliac occlusive disease.
Using peritoneal and blood lactate as predictor of condition type, surgical referral and prognosis in equine colic cases
Authors: Taschetto P.M. , Pradella G.D. , Berlingieri M.A. , Leiria P.A.T. , Skupien J.A. , Lübeck I. , Duarte C.A.
Published: July 2023

ABSTRACT It is important to investigate fast and accurate equine colic syndrome diagnostic forms. Lactate results from anaerobic glycolysis; high levels of it may indicate intestinal disorders with tissue hypoperfusion and hypoxia. The current study aims at investigating whether blood and peritoneal lactate values observed when horses with colic syndrome were hospitalized, were associated with condition type, therapeutic referral, and survival rates. Retrospective analysis was applied to 498 medical records of animals with colic syndrome, at EQUIVET Hospital -SP; 89 cases were herein selected. Based on logistic regression, peritoneal lactate played a more significant part than blood in variables like obstruction type and survival rates. Surgical cases comprised 52.8% of analyzed animals; strangulation changes, 26%; and overall survival, 62.9%. Mean blood and peritoneal lactate level in animals showing strangulation changes reached 5.11 and 7.33mmol/L, whereas non-strangulation cases recorded 3.54 and 3.06mmol/L, respectively. On the other hand, mean blood and peritoneal lactate level recorded for survivors reached 3.43 and 2.42mmol/L, whereas non-survivors recorded 4.84 and 7.13mmol/L, respectively. We concluded that peritoneal lactate measured when horses with colic syndrome were hospitalized was a predictor of condition type, and of animal survival and prognosis. However, blood and peritoneal lactate measurements did not contribute to therapeutic referral.
Zootechnical performance, degree of steatosis and the genotoxic potential in yellowtail tetra Astyanax lacustris fed with different levels of L-carnitine
Authors: Martins L.F. , Silva W.V. , Nascimento N.F. , Melo M.P. , Crispim B.A. , Barufatti A. , Hilbig C.C.
Published: July 2023

ABSTRACT L-carnitine perform a major role in transporting long-chain fatty acids into the mitochondria, where they are oxidized. It has been used in animal diets to decrease fat and increase muscle protein. The aim of this study was to evaluate the zootechnical performance, degree of steatosis in the liver, and genotoxic potential in Astyanax lacustris fed with different levels of L-carnitine (LC). Yellowtail tetra juveniles (n = 140) were distributed in 20 tanks of 70 L, with seven fish in each, in a water recirculation system with controlled temperature (27±0.1⁰C). The treatments with different levels of L-carnitine supplementation were: 0 (control), 250, 500, 750, and 1000 mg of LC per kg of food. The diets were provided twice a day for 60 days. The results showed that the different levels of LC did not affect (P>0.05) weight gain, survival, viscerosomatic index, and the liver hepatocytes showed a normal appearance. However, the use of LC supplementation showed genotoxic potential with a significant difference (P<0.05) for cell alterations when compared to the control at concentrations above 500mg kg-1.
Sarcocystis spp. detection in cattle using different diagnostic methods
Authors: Ferreira Maiara S.T. , Fernandes Fagner D’ambroso , Bräunig Patrícia , Guerra Renata R. , Sangioni Luis Antonio , Vogel Fernanda S.F.
Published: July 2023

ABSTRACT: Cattle are considered intermediate hosts of Sarcocystis, which can cause clinical signs and lower performance in the acute phase of infection. Sarcocystis spp. are usually not visible to the naked eye during the post mortem inspection. Moreover, fresh microscopic examination and transmission electron microscopy techniques are difficult to apply to large samples. Therefore, extensive studies on Sarcocystis infection in cattle using molecular and serological methods are required. Here, we investigated Sarcocystis spp. infection in cattle using fresh microscopic examination and polymerase chain reaction of myocardium samples and compared the results with the presence of antibodies against Sarcocystis spp. in corresponding serum samples detected using indirect fluorescent antibody test. Microscopic Sarcocystis were observed in 100% of the myocardial samples, and Sarcocystis DNA was present in 86% (43/50) of these samples. Antibodies against Sarcocystis spp. were detected in 96% (48/50) and 80% (40/50) of the serum samples at 1:25 and 1:200 dilutions, respectively. The three associated methods (fresh microscopic examination, PCR and serology) showed good sensitivity and detection for Sarcocystis spp. compared with fresh microscopic examination (only), and they may facilitate diagnosis in live animals on a large scale as well as monitoring of the herd status.
Ductus venosus as a marker of fetal growth in first trimester in a population of Colombian pregnant women
Authors: Ramírez Mauricio Andrés Martínez , Gamboa Valentina María Vargas , Infante Ximena Carolina Romero , Calvo Montserrat Uriel , Hernández Arlín Martha Bibiana Pérez
Published: July 2023

Abstract Objectives: to evaluate the relationship between the ductus venosus (DV) and the variables of fetal growth in the first trimester in a Colombian pregnant population. Methods: a descriptive cross-sectional study was carried out with secondary data obtained from a multicenter study.526 patients were included between weeks 11 and 14 for gestational ultrasound follow-up attended in three health care institutions in Bogotá, Colombia, between May 2014 and October 2018. A bivariate descriptive analysis was carried out where the relationship between the characteristics of the DV in the first trimester and ultrasound findings. Results: the flow wave of the DV in the first trimester was normal in the entire sample, with a pulsatility index of the ductus venosus (DVPI) of 0.96±0.18. In addition, a negative correlation was found between the crown-rump length (CRL) and the DVPI (p<0.05). Conclusion: there is a relationship between the DVPI regarding the CRL, indicating an interest in this early marker in relation to fetal growth alterations; however, more studies are required to determine the usefulness of this variable with respect to fetal growth.
Histórias contaminadas: alianças ambientais das comunidades pesqueiras e quilombolas contra a violência lenta do petróleo na Baía de Todos os Santos
Authors: Buti Rafael Palermo
Published: July 2023

Resumo Baseado em duas situações de vazamento ocorridas em 2018, o artigo apresenta a violência lenta do petróleo na Baía de Todos os Santos. Com ele, pretendo contribuir para as abordagens antropológicas sobre percepções e impactos ambientais na longa duração a partir de três dimensões de análise. Na primeira, mostro as formas de produção da violência lenta do petróleo, vinculadas aos mecanismos de negação de sua realidade por parte da Petrobras e do poder público. Na segunda, descrevo de que modo as comunidades pesqueiras e quilombolas da região a ela se opõem, articulando seus direitos na esfera judicial e no debate público através da intersecção das agendas ambiental, racial, de gênero e climática. E, por fim, revelo as formas de inscrição da violência lenta do petróleo nos ambientes costeiros da Baía de Todos os Santos, estimulando um olhar sobre a produção de paisagens e habitabilidades na longa duração.
O rio e a época: entendências barranqueiras sobre a água na paisagem perturbada do Vale do São Francisco
Authors: Benites Luiz Felipe Rocha
Published: July 2023

Resumo Este artigo tem por objetivo expor parte do emaranhamento que envolve o modo de habitar de ribeirinhos do Vale do Alto-Médio São Francisco, também chamados barranqueiros, com as águas e entes outros-que-humanos que compõem a paisagem (co)construída às margens do rio. O ponto de partida para descrever criticamente essa socialidade mais-que-humana às margens do Rio São Francisco são as entendências dos habitantes da comunidade de Ribanceira, no município de São Romão, em Minas Gerais, sobre as águas em seus fluxos pluviais e fluviais. Imersos na alternância cíclica entre o tempo das águas e o tempo da seca, que orientam suas atividades de pesca e de roça, os barranqueiros da Ribanceira tem vivenciado fluxos pluviais cada vez menos frequentes e intensos, bem como experimentado o convívio com um rio preocupantemente sem corrida que dá cores às narrativas em tons desalentadores sobre a proximidade da época ou fim dos tempos.
Three planned experiments in environmental education in rural sectors of southern Chile
Authors: Muñoz-Pedreros Andrés , Pantoja Jorge , Morandé Ximena , Möller Patricia , Morales Jorge
Published: July 2023

Abstract Environmental education (EE) must be carried out following a permanent programme, and should be a source of inspiration to encourage the incorporation of an ‘environmentalist’ line in other cultural and educational materials. EE has developed in Chile since the 1970s, but slowly, and unconnected with three important actors: the State, the universities, and non-governmental organisations. We implemented an EE programme across a set of other programmes (e.g. rural development, wetland management, biodiversity, and biological pest control), with the following objects: (a) to develop applied research in the field of EE; (b) to produce teaching materials; (c) to develop formal and informal training in EE. The object of the present work is to present three planned experiments in environmental education carried out since 1991 in different ecosystems and with different social actors.
Percepção de indígenas Kaingang acerca da política ambiental no Brasil no século XXI
Authors: Ayres Ariadne Dall’acqua , Antiqueira Lia Maris Orth Ritter , Brando Fernanda da Rocha
Published: July 2023

Resumo O cenário brasileiro na segunda década do século XXI exige atenção no que diz respeito às questões ambientais com consequências às comunidades indígenas do país. No artigo, propõe-se discutir relatos de representantes indígenas quanto ao aumento da veiculação de notícias acerca da devastação ambiental com debates sobre mudanças na política socioambiental do país. Sob aportes teóricos que destacam essas problemáticas em populações indígenas, utiliza-se entrevistas realizadas com indígenas Kaingang. A partir de suas narrativas, discute-se o cenário socioambiental do Brasil e a veiculação de notícias acerca do tema. Permeando a literatura com as narrativas produzidas, entende-se que este cenário socioambiental é sentido tanto na perspectiva afetiva como cognitiva, mostrando entendimentos acerca da posição marginalizada que os governos tratam as populações indígenas e o meio ambiente.
Desenvolvimento de questionário para indicar posicionamentos em relação às Sociedades Sustentáveis partindo de conceitos correlatos
Authors: Santos Leandro F. A. , Arruda Luís Gustavo , Damasceno Marilua , Laham Beatriz Sinelli , Costa-Pinto Alessandra B.
Published: July 2023

Resumo Apresenta-se o processo de elaboração do Índice Composto de Concepções Socioambientais (ICCSA): um questionário modelo multi-resposta que aborda os temas da Educação Ambiental, Sustentabilidade e Meio Ambiente sob a ótica da transição para Sociedades Sustentáveis. Durante o processo de elaboração foram realizadas duas fases de análises de consistência interna e validade, com a participação de especialistas. A versão final do ICCSA apresenta 43 afirmações, dispostas em seis dimensões, sugerindo suficiência quanto à confiabilidade interna e validades de conteúdo e discriminante. Os resultados mostram que o instrumento pode ser utilizado para indicar os posicionamentos em relação à transição para Sociedades Sustentáveis. Recomenda-se a realização de estudos futuros, com populações maiores, para complementar as análises de confiabilidade e validade com participantes não especialistas. O ICCSA encontra-se disponível para pesquisadoras que quiserem utilizá-lo.
Environmental Impacts of Telecoupling of the Urban Consumption System of Organic Foods
Authors: Schmitz Anelise , Jordan Elaine , Gadda Tatiana Maria Cecy
Published: July 2023

Abstract The environmental impacts of the food system, especially the distances covered, are not clear to the final consumer. The aim was to evaluate and calculate the urban telecoupling and the environmental impacts and calculate the energy consumption and the environmental emissions of the organic foods. Through the calculation of quantities, distances, losses and the analysis of telecouplings, we measured Greenhouse Gas (GG) emissions, as well as the energy and carbon footprints of organic foods traded at the CEASA/PR, Curitiba. Emissions had a low environmental impact because the largest quantities of transported organics originate from production sites located within the greater Curitiba region. The study showed a consumption pattern supporting food produced in regions adjacent to the trading center in safe and healthy and safe way, which may be associated with a greater awareness of the environmental impacts resulting from the distances covered.
Book review: Transforming universities in the midst of global crisis: A university for the common good
Authors: Ratuva Steven
Published: July 2023

Abstract This article provides a review of Transforming Universities in the Midst of Global Crisis: A University for the Common Good, authored by Richard Hil, Kristen Lyons and Fern Thompsett.
ESTRESSE E SOFRIMENTO EM ENFERMEIROS HOSPITALARES: RELAÇÃO COM VARIÁVEIS PESSOAIS, LABORAIS E HÁBITOS DE VIDA
Authors: Medeiros Sílvia Elizabeth Gomes de , Aquino Jael Maria de , Arruda Gustavo Aires de , Robazzi Maria Lúcia do Carmo Cruz , Gomes Betânia da Mata Ribeiro , Andrade Maria Sandra , Monteiro Estela Maria Leite Meirelles
Published: July 2023

RESUMO Objetivo: identificar as possíveis associações entre o estresse e o sofrimento com as variáveis pessoais, laborais e hábitos de vida. Método: estudo transversal, quantitativo, exploratório, correlacional, realizado no período de junho de 2019 a fevereiro de 2020. Os dados sobre as características pessoais, hábitos de vida e as condições de trabalho foram obtidos com a aplicação de questionário. Para avaliação do estresse, utilizou-se o Inventário de Estresse em Enfermeiros e, para o sofrimento, aplicou-se a Escala de Indicadores de Prazer e sofrimento no Trabalho, ambos nas versões brasileiras. Resultados: o estresse esteve associado à insatisfação com a remuneração, indicadores de sofrimento e interesse em mudar de emprego e profissão. As comparações entre os indicadores de sofrimento e os domínios de investigação do estresse foram significativas. Conclusão: o estresse vivenciado na atividade laboral do enfermeiro recebe forte influência da baixa remuneração, levando-o a desejar mudar de emprego e profissão. O esgotamento profissional e a falta de reconhecimento são estressores que impulsionam mecanismos de defesa, dentre eles, o desejo de mudar de emprego.
COMPETÊNCIAS PARA PRÁTICAS DE EVACUAÇÕES AEROMÉDICAS EM EMERGÊNCIAS E DESASTRES: REVISÃO DE ESCOPO
Authors: Haberland Débora Fernanda , Silva Thiago Augusto Soares Monteiro da , Kneodler Thais da Silva , Guilherme Fábio José de Almeida , Borges Letícia Lima , Oliveira Alexandre Barbosa de
Published: July 2023

RESUMO Objetivo: mapear as competências desenvolvidas em estratégias de capacitação para práticas de transporte aéreo de pacientes, diante de situações de emergência e desastres envolvendo agentes químicos, biológicos, radiológicos e nucleares (QBRN). Método: revisão de escopo estruturada conforme as recomendações do Joanna Briggs Institute e do checklist Preferred Reporting Items for Systematic reviews and Metanalyses extension for Scoping Reviews. O estudo foi desenvolvido em cinco etapas: busca de fontes em 17 bases de dados, um portal de informação e dois repositórios de literatura cinzenta, utilizando 125 descritores DeCS, MeSH e Emtree, sem recorte temporal e idiomático; seleção; leitura crítica na íntegra dos textos selecionados por dois revisores em duplo cego; síntese dos resultados e apresentação das competências mapeadas. Resultados: foram analisados 878 estudos, dos quais 18 compuseram a amostra. Ao todo, foram mapeadas 11 competências, com destaque para o domínio capacitação técnica. As competências referem-se especialmente ao conhecimento técnico-científico em situações de desastre envolvendo agentes QBRN e à segurança do paciente e dos profissionais envolvidos. Conclusão: a operacionalização de artifícios para aperfeiçoar os processos de capacitação baseados em competências mostrou-se estratégica para elevar a qualidade e a segurança das práticas de transporte aéreo de pacientes. A abordagem das fontes sobre aspectos específicos das particularidades das práticas relacionadas às emergências e desastres envolvendo agentes QBRN em processos de formação/capacitação demonstra o esforço acadêmico de promover a redução do risco desses eventos quando, oportunamente, forem acionadas instituições civis e militares e seus operadores de saúde.
CACTO DEVELOPMENT: CARE PROGRAM FOR MOTHERS OF CHILDREN WITH CONGENITAL ZIKA SYNDROME
Authors: Vale Paulo Roberto Lima Falcão do , Costa Jessica Santos Passos , Freitas Katia Santana , Lacerda Maria Ribeiro , Carvalho Rosely Cabral de , Carvalho Evanilda Souza de Santana
Published: July 2023

ABSTRACT Objective: to develop a unitary caring program for mothers of children with Congenital Zika Syndrome. Method: this is a methodological study, based on Unitary Caring Science, developed in two phases: creation, consisting of six moments, and content validity, through the participation of 36 experts on the subject, professional caregivers and mothers. The Content Validity Index and the Content Validity Ratio were used for data analysis. Results: the program was named CACTO, composed of seven care modalities: Taking care of my mind; Upright and correct position; Taking care of my sleep; Family that is together; Mirror mirror on the wall; Mother who takes care of mother; Facing prejudices. CACTO was validated with a Content Validity Index ≥0.88 and critical Content Validity Ratio values greater than or equal to the cutoff point defined for each group of experts. Conclusion: the translation of Unitary Caring Science into a care program encourages professionals to promote innovative care, valuing acceptance, autonomy, citizenship and critical awareness, advocating in favor of emancipatory interactional care. CACTO is a technological innovation that can transform professional care, promote the resolution of mothers’ health needs and enhance the quality of life of children with Congenital Zika Syndrome, family and caregivers themselves.