bluuebunny/crossref_metadata_2025 huggingface dataset:
Optimalisasi Sistem Absensi Online Pada Lembaga Pendidikan Privat Panggil Guru Pekanbaru
Authors: Herlandy Pratama Benny , Vitriani  , Effendi Noverta , Anggraini Lusi
Published: December 2021

Panggil Guru (PAGU) merupakan salah satu lembaga bimbingan beljar yang terdapat di Kota Pekanbaru yang melayani jasa belajar privat dan kelompok yang masih menerapkan sistem manajemen operasional dan pembelajaran yang bersifat konvensional. Mulai dari kegiatan pendaftaran, penjadwalan, pembayaran dan pelaksanaan pembelajaran serta penilaian hasil belajar bersifat konvensional tanpa memiliki sistem yang terpadu dan berbasis teknologi informasi. Penerapan sistem ini memberikan dampak terhadap tingginya biaya operasional yang diperlukan dan rendahnya minat peserta didik untuk belajar bersama PAGU. Selain pendampingan pengembangan sistem, kegiatan kemitraan ini juga bertujuan untuk meningkatkan kompetensi tutor di PAGU dalam mengembangkan materi pelajaran berbasis teknologi informasi dan meningkatkan kemampuan operasional administrator di PAGU untuk mengelola sistem terintegrasi berbasis teknologi informasi yang telah dikembangkan melaui pelatihan. Adapun target luaran yang ingin dicapai melalui kegiatan kemitraan ini adalah peningkatan pemberdayaan mitra dalam bidang manajemen, publikasi pada media massa cetak, dan dokumentasi program kemitraan yang dirangkum dalam bentuk video pelaksanaan kegiatan serta media promosi UMRI. Program kemitraan yang diusulkan terbagi atas 5 (lima) tahapan yaitu menjalin kerjasama, analisis kebutuhan dan perancangan, pengembangan sistem manajemen terintegerasi, pelatihan peningkatan kompetensi serta kegiatan evaluasi dan monitoring pelaksanaan progam kemitraan.
COVID-19 in a child with multiple comorbidities
Authors:   ", Sandu Elena-Cristina ,   Dr Victor Babes",   Clinical Hospital of Infectious and Tropical Diseases, Bucharest, Romania, Vancea Geta ,   "Dr Victor Babes" Clinical Hospital of Infectious and Tropical Diseases, Bucharest, Romania,   "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania, Voicu-Pârvu Nicoleta ,   "Dr Victor Babes" Clinical Hospital of Infectious and Tropical Diseases, Bucharest, Romania, Ispas Dana ,   "Dr Victor Babes" Clinical Hospital of Infectious and Tropical Diseases, Bucharest, Romania, Scurtu Gabriela ,   "Dr Victor Babes" Clinical Hospital of Infectious and Tropical Diseases, Bucharest, Romania, Tudor Nicoleta ,   "Dr Victor Babes" Clinical Hospital of Infectious and Tropical Diseases, Bucharest, Romania, Stoenescu Andreea Florentina ,   "Dr Victor Babes" Clinical Hospital of Infectious and Tropical Diseases, Bucharest, Romania,   "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania, Chirilă Claudia ,   "Dr Victor Babes" Clinical Hospital of Infectious and Tropical Diseases, Bucharest, Romania, Popescu Raluca ,   "Dr Victor Babes" Clinical Hospital of Infectious and Tropical Diseases, Bucharest, Romania, Florescu Simin-Aysel ,   "Dr Victor Babes" Clinical Hospital of Infectious and Tropical Diseases, Bucharest, Romania,   "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania, Ceaușu Emanoil ,   "Dr Victor Babes" Clinical Hospital of Infectious and Tropical Diseases, Bucharest, Romania,   "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania,   Academy of Medical Sciences, Romania
Published: December 2021

A female child, 1 year-old and 2 months, diagnosed with multiple neurological conditions, including myelomeningocele and operated hydrocephalus, was diagnosed with SARS-CoV-2 in October 2020 and hospitalized in our clinic. At the time of the onset of the disease, the patient had a febrile episode, laboratory blood tests showed a slightly increased biological inflammatory syndrome, and mixed pneumonia was described radiologically. Thus, antibiotic treatment was initiated, with laboratory tests and control imaging within normal limits after several days of admission. Being an institutionalized child, according to the epidemiological recommendations of that time, she was hospitalized in our clinic during the 14 days of the illness. Thus, on the 15th day of the disease she was discharged, with negative SARS-CoV-2 control RT-PCR, with good general condition, afebrile over 10 days.
Neuroplasticity Mechanisms and Prospects for Personalized Rehabilitation Strategies in Patients with Motor and Cognitive Impairments
Authors: Shagaeva Kristina A. , Shagaev Artur S.
Published: December 2021

Aim. To highlight the most important areas of research on the problems of rehabilitation after stroke and the prospects for the development of new rehabilitation strategies, taking into account individual characteristics. Neuroplastic outcomes of anemic infarctions are presented by multi-pattern positive processes of synaptogenesis, sprouting, synthesis of neuroprotective proteins, and destructive effects of stress plasticity inducing dystonic disturbances, deterioration of stabilometric parameters and locomotor gait mechanisms with support deterioration [1]. Thus, specialists in neurorehabilitation should know the basics of fundamental neurophysiological processes in the central nervous system, interhemispheric networks of the brain, and optimize rehabilitation programs, taking into account individualized recovery profiles [2]. One of the factors influencing recovery after a stroke is nervous reorganization, which is proportional to the amount of damage [3]. The processes of neuroplasticity are studied from the standpoint of returning to the pre-stroke recovery model (with minor injuries) – forming “optimal” plasticity and compensatory strategies of “destructive” plasticity (with extensive hemispheric injuries). Micro-RNA (miRNA) are understudied in the neuroprotective reaction to cerebral ischemia. Another important modulator of stroke outcomes is the brain-derived neurotrophic factor (BDNF). Processing of the defective BDNF synthesis when the amino acid valine is replaced by methionine (val-met) that occurs during allelic disorders is of outstanding interest.
Conclusion. Promising research areas for strategic approaches to rehabilitation after a stroke are the study of hemispheric introduction, miRNA and neuroprotection cascades; BDNF as an inducer of neuronal differentiation. Allelic BDNF polymorphisms induce lower recovery potential after stroke. Under certain environmental conditions motor learning can overcome the neuroplasticity deficit in the BDNF gene polymorphism. The studies have shown general patterns of positive effects of aerobic stimuli with enhanced BDNF secretion in the recovery of patients with cognitive and motor impairments; nevertheless, the onset period, intensity, duration and exercises rhythmicity have not been established in cerebral stroke. Future studies are likely to optimize rehabilitation profiles based on genetic characteristics.
Experience of Outpatient Rehabilitation of Patients after Pneumonia Associated with the New Coronavirus Infection COVID-19
Authors: Nesina Irina A. , Golovko Elena A. , Shakula Alexander V. , Figurenko Natalia N. , Zhilina Irina G. , Khomchenko Tatiana N. , Smirnova Elena L. , Chursina Valeria S. , Koroleva Anna V.
Published: December 2021

The revealed functional disorders in patients who have suffered pneumonia associated with the new coronavirus infection COVID-19 require long-term rehabilitation, in particular in outpatient environment.
Aim. To evaluate the effectiveness of outpatient rehabilitation of patients who have suffered pneumonia associated with the new coronavirus infection COVID-19.
Material and methods. The study included 72 patients after mild to moderate pneumonia associated with the new coronavirus infection COVID-19. The main group included 37 patients who underwent comprehensive rehabilitation, including physical therapy, massage, magnetic therapy, speleotherapy, cognitive behavioral therapy, and drug therapy. The comparison group (35 patients) received physical therapy, magnetic therapy and drug therapy. The effectiveness of therapy was assessed on the basis of standardized questionnaires and scales: Asthenia scale (MFI-20), Anxiety and Depression scale (HADS), mMRC and Borg dyspnea scales, clinical and laboratory examination data. The quality of life of patients in the dynamics of rehabilitation was assessed by the quality of life questionnaire (EQ-5D).
Results and discussion. In the main group of patients, the effectiveness of rehabilitation was higher relative to the decrease in the severity of dyspnea, asthenia, normalization of lymphocyte levels. In this group, the quality of life improved more significantly on the scales of anxiety/depression and psychoemotional status.
Conclusion. The rehabilitation program, which additionally included chest massage, speleotherapy, transcranial electrical stimulation (TES), showed an advantage in improving clinical and laboratory parameters and quality of life in patients who have suffered pneumonia associated with the new coronavirus infection COVID-19.
Vestibular Rehabilitatiоn in Vestibular Migraine
Authors: Illarionova Еlena М. , Gribova Natalya P.
Published: December 2021

The search for possible ways to minimize dizziness in patients with vestibular migraine is especially relevant in the aspect of individualized complex vestibular rehabilitation.
Aim. To study the possibilities of complex individualized vestibular rehabilitation in patients with vestibular migraine.
Material and methods. The study included 122 patients (40 men and 82 women) aged 18 to 50 years, with significant vestibular migraine. We used the Dizziness Handicap Inventory scale for assessing dizziness and a 5-point Scale for subjective assessment of the severity of dizziness and a special complex method including a set of vestibular exercises, a method of the computer stabilometry with biofeedback. Objective control of vestibular rehabilitation was carried out with the help of stabilometric testing.
Results and discussion. Positive dynamics were observed when analyzing the data of the physical, functional and emotional subscales of the Dizziness Handicap Inventory and the Scale of Subjective Assessment of the Dizziness Severity. In addition, the presented stabilometric diagnostics made it possible to fix the difference between the initial condition of patients with vestibular dysfunction and after 3 months of the special vestibular rehabilitation.Тhere was a statistically significant decrease in the basic stabilometric parameters: the area of the statokinesiogram (median area, mm² – 254 (95% CI 222-285)) and the rate of deviation of the center of pressure (median speed, mm/s – 21 (95% CI 17-24)) as well as a decrease in the shifts of the spectrum energy in the low-frequency and high-frequency spectrum that indicates an improvement in stability. The presented method for influencing the compensatorycapabilities of regulatory mechanisms in patients with vestibular migraine positively affects the efficiency of the equilibrium system as a whole, optimizing postural stability in this category of patients.
Conclusion. An individually selected comprehensive program of vestibular gymnastics and hardware rehabilitation techniques on the stabilographic platform with biofeedback helps to improve postural stability and minimize dizziness in patients with vestibular migraine.
The Effect of the Vitamin D Receptor on Bone Metabolism Disorders in Premature Infants Born Using In Vitro Fertilization
Authors: Druzhinina Natalia A. , Merzlyakova Dinara R. , Hafizova Naila R. , Gorbunova Valentina Yu. , Imaeva Lilia R. , Vahitova Gulnaz A. , Khalikova Lilia R.
Published: December 2021

Aim. To study the effect of the vitamin D receptor on bone metabolism disorders in premature infants born using in vitro fertilization (IVF).
Material and methods. A study was conducted on 189 premature infants, divided into 2 groups. The first group is premature babies born using the IVF method. The second group – children were born naturally. The VDR receptor gene was analyzed depending on the observation groups.
Results. It was found that in children born with IVF, the signs of osteopenia were more pronounced. Genetic studies have shown that the frequency of mutant allele *B and homozygous mutant genotype B/B of the VDR gene is more common in premature babies born with IVF. Mutant homozygous genotype B/B occurs in the main group of children with a frequency of 35%, which is significantly higher than in the control group of children (17%). Changes in bone metabolism are one of the important causes of musculoskeletal system disorders, which is closely associated with the molecular genetic polymorphism of the VDR gene.
Conclusion. The studies conducted led to the following conclusion: the frequency of the mutant allele *B and homozygous for the mutant allele genotype B/B, occurs more often in premature babies born using IVF. The frequency of the *B allele in the group of premature babies born using IVF is 50%, which is higher than in the group of premature babies born naturally (40%). However, the identified genetic differences are not associated with the IVF procedure. These are combinations of gene alleles inherited from the parents. Knowledge of hereditary risk factors for low vitamin D3 levels can be of great practical importance for predicting bone metabolism disorders in premature infants.
Prospects for the development of geothermal energy supply
Authors: Stennikov V.A. , Batmunkh S. , Sokolov P.A.
Published: December 2021

The paper addresses methodological and technological issues of building environmentally friendly and efficient energy supply based on geothermal energy sources. Geothermal potential in the world, accentuating that in Russia (areas of the Baikal natural territory) and Mongolia, is analyzed considering the possibility of its implementation in the thermal power industry.
Geothermal areas of Central Mongolia are characterized by increased heat flows and occurrences of thermal waters. The most promising thermal spring occurrences are the Shivert, Shargalzhuut, Tsenkher, Otgontenger, and Khuzhirt, to name some of them. Currently, the thermal energy potential of the Khangai arched uplift in Central Mongolia is employed to heat industrial, agricultural, and civil facilities. There are also plans to consider the possibility of large-scale employment of thermal waters of the region for electricity generation.
An example of using geothermal waters for electricity generation is given, and the possibility of establishing a heating system in the city of Tsetserleg based on a geothermal heat pump unit with a wind power plant is assessed.
A Sharp Lieb-Thirring Inequality for Functional Difference Operators
Authors:   Imperial College London, UK, Laptev Ari , Schimmer Lukas ,   Institut Mittag-Leffler, Sweden
Published: December 2021

We prove sharp Lieb-Thirring type inequalities for the eigenvalues of a class of one-dimensional functional difference operators associated to mirror curves. We furthermore prove that the bottom of the essential spectrum of these operators is a resonance state.
Prevalence of Extra Power-Law Spectral Components in Short Gamma-Ray Bursts
Authors: Tang Qing-Wen , Wang Kai , Li Liang , Liu Ruo-Yu
Published: December 2021

A prompt extra power-law (PL) spectral component that usually dominates the spectral energy distribution below tens of keV or above ∼10 MeV has been discovered in some bright gamma-ray bursts (GRBs). However, its origin is still unclear. In this paper, we present a systematic analysis of 13 Fermi short GRBs, as of 2020 August, with contemporaneous keV–MeV and GeV detections during the prompt emission phase. We find that the extra PL component is a ubiquitous spectral feature for short GRBs, showing up in all 13 analyzed GRBs. The PL indices are mostly harder than −2.0, which may be well reproduced by considering the electromagnetic cascade induced by ultrarelativistic protons or electrons accelerated in the prompt emission phase. The average flux of these extra PL components positively correlates with that of the main spectral components, which implies they may share the same physical origin.
Simulation of the Scattering of Continuously Injected Pickup Ions outside the Heliopause
Authors: Sheng Ding , Liu Kaijun , Florinski V. , Perez J. D.
Published: December 2021

Hybrid simulations in 2D space and 3D velocity dimensions with continuous injection of pickup ions (PUIs) provide insight into the plasma processes that are responsible for the pitch angle scattering of PUIs outside the heliopause. The present investigation includes for the first time continuous injection of PUIs and shows how the scattering depends on the energy of the PUIs and the strength of the background magnetic field as well as the dependence on the injection rate of the time for the isotropization of the pitch angle distribution. The results demonstrate that, with the gradual injection of PUIs of a narrow ring velocity distribution perpendicular to the background magnetic field, oblique mirror mode waves develop first, followed by the growth of quasiparallel propagating ion cyclotron waves. Subsequently, the PUIs are scattered by the excited waves and gradually approach an isotropic distribution. A time for isotropization is defined to be the time at which T
∣∣/T
⊥, i.e., the ratio of the parallel to perpendicular PUI thermal energy changes from ≈0 to ≈0.15. By varying the PUI injection rate, estimates of the time for the PUI distribution to be isotropized are presented. The isotropization time obtained is shorter, ≈ months, than the time, ≈ years, required by the conventional secondary ENA mechanism to explain the IBEX ENA ribbon.
Benchmarking Multiconfiguration Dirac–Hartree–Fock Calculations for Astrophysics: Si-like Ions from Cr xi to Zn xvii
Authors: Zhang X. H. , Del Zanna G. , Wang K. , Rynkun P. , Jönsson P. , Godefroid M. , Gaigalas G. , Radžiūtė L. , Ma L. H. , Si R. , Xiao J. , Chen Z. B. , Yan J. , Wu Y. , Chen C. Y.
Published: December 2021

The multiconfiguration Dirac–Hartree–Fock (MCDHF) and relativistic configuration interaction methods are used to provide excitation energies, lifetimes, and radiative transition data for the 604 (699, 702, 704, 704, 704, and 699) lowest levels of the 3s
23p
2, 3s3p
3, 3s
23p3d, 3p
4, 3s3p
23d, 3s
23d
2, 3p
33d, 3s3p3d
2, 3s3d
3, 3p3d
3, 3p
23d
2, 3s
23p4s, 3s
23p4p, 3s
23p4d, 3s
23p4f, 3s3p
24s, 3s3p
24p, 3s3p
24d, 3s3p
24f, 3s
23d4s, 3s
23d4p, 3p
34s, 3p
34p, 3s3p3d4s, 3s
23p5s, and 3s
23p5p configurations in Cr xi, (Mn xii, Fe xiii, Co xiv, Ni xv, Cu xvi, and Zn xvii). Previous line identifications of Fe xiii and Ni xv in the EUV and X-ray wavelength ranges are reviewed by comprehensively comparing the MCDHF theoretical results with available experimental data. Many recent identifications of Fe xiii and Ni xv lines are confirmed, and several new identifications for these two ions are proposed. A consistent atomic data set with spectroscopic accuracy is provided for the lowest hundreds of levels for Si-like ions of iron-group elements of astrophysical interest, for which experimental values are scarce. The uncertainty estimation method suggested by Kramida, applied to the comparison of the length and velocity line strength values, is used for ranking the transition data. The correlation of the latter with the gauge dependency patterns of the line strengths is investigated.
Re-irradiation for recurrent or second primary head and neck cancer
Authors: Lee Hye In , Kim Jin Ho , Ahn Soon-Hyun , Chung Eun-Jae , Keam Bhumsuk , Eom Keun-Yong , Jeong Woo-Jin , Kim Ji-Won , Wee Chan Woo , Wu Hong-Gyun
Published: December 2021

Purpose: To investigate the efficacy and safety of intensity-modulated radiotherapy (IMRT)-based re-irradiation (reRT) for recurrent or second primary head and neck cancer (HNC).Materials and Methods: Patients who underwent IMRT-based reRT for recurrent or second primary HNC between 2007 and 2019 at two institutions were included. Medical records and dosimetric data were retrospectively reviewed. Overall survival (OS), progression-free survival (PFS), severe late toxicities, and clinicopathological prognostic factors were analyzed.Results: A total of 42 patients were analyzed. With a median follow-up of 15.1 months (range, 3.7 to 85.8 months), the median OS was 28.9 months with a 2-year OS rate of 54.6%. The median PFS and 2-year PFS rates were 10.0 months and 30.9%, respectively. Multivariate analysis showed that good performance (Eastern Cooperative Oncology Group [ECOG] 0 or 1), a longer time interval (≥24 months) between radiotherapy courses, and higher reRT dose (>60 Gy) were significantly favorable factors for OS (all p < 0.05). Higher reRT dose and salvage surgery were significantly associated with improved PFS (all p < 0.05). Regarding the Multi‐Institution Reirradiation (MIRI) Collaborative RPA classification, the 2-year OS rates of each class were 87.5% in class I, 51.8% in class II, and 0% in class III (p = 0.008). Grade ≥3 late toxicity was reported in 10 (23.8%) patients. There was no significant factor associated with increased late toxicities.Conclusion: IMRT-based reRT should be considered as a treatment option for patients with recurrent or second primary HNC. Further trials are needed to establish a subset of patients who may benefit from reRT without severe late toxicity.
Fish occurrence in the Kuban River Basin (Russia)
Authors: Artaev Oleg , Pashkov Andrey , Vekhov Dmitriy , Saprykin Maksim , Shapovalov Maksim , Levina Marina , Levin Boris
Published: December 2021

This publication describes a dataset containing information on 1328 occurrences of fishes in the Kuban River Basin, the longest river of Northern Caucasus and representing its own freshwater ecoregion (428 Kuban Ecoregion). All observations have precise geo-referencing with the names of water bodies (rivers, lakes etc.). The dataset is based on both literature data (509 occurrences) and our own sampling (814 occurrences). Observations were carried out between 1889 and 2020.

The majority (> 61%) of occurrences in the presented data are published for the first time. This extended dataset contributes significantly to fish fauna survey in the Kuban River ecoregion.
Four new species of the spider genus Synagelides Strand, 1906 from South China (Araneae, Salticidae)
Authors: Li Bing , Wang Cheng , Peng Xian-Jin
Published: December 2021

Four new species of the jumping spider genus Synagelides Strand, 1906 from Guizhou and Yunnan, China are described: Synagelides angustussp. nov. (♀), S. latussp. nov. (♂♀), S. subagoriformissp. nov. (♂♀), and S. triangulussp. nov. (♀). Photographs of the habitus and copulatory organs and a distributional map are provided.
A Roadmap for Getting a Project Approved
Authors: Trepanier Sylvain
Published: December 2021

Nurse educators are filled with ideas to better workforce members and create a safe environment for patients. Since most programs require funding, nurse educators must include the return on the investment as part of their business case.

[
J Contin Educ Nurs
. 2021;52(12):549.]
Educating and Transitioning a Diverse Nursing Workforce: LPN to BSN
Authors: Huun Kathleen M. , Kummerow Andreas , Jenkins Jacob T.
Published: December 2021

Licensed practical nurses (LPNs) represent ethnic diversity, gender diversity, and generational diversity within a marginalized workforce. Their advancement to the baccalaureate nursing degree (BSN) may enhance delivery of culturally relevant patient care and reduce disparity in health care. Based on Knowles Andragogy in Practice model, we created a self-paced, individualized educational pathway with a focus on diversity, equity, and inclusion to address their needs. Dotting the I's (idea, implementation, innovation, inclusion, improvement) illustrates track/curriculum development, whereas crossing the T's (time, travel, tuition, transition, technology, touchstones) alleviates student burdens. The elements are interwoven into the LPN-to-BSN transition journey model, as aligned with core and subcore concepts of transitioning.

[
J Contin Educ Nurs
. 2021;52(12):558–564.]
Adapting Civility Education in an Academic-Practice Partnership
Authors: Opsahl Angela G. , Embree Jennifer L. , Howard Matthew S. , Davis-Ajami Mary Lynn , Herrington Cynthia , Wellman Debra S. , Hodges Kimberly T.
Published: December 2021

Background:

Incivility results in nurse burnout, decreased job performance, and decreased patient safety. Leaders of an academic-practice partnership developed educational activities promoting organizational civility during the COVID-19 pandemic. The purpose of this article is to describe an educational activity about civility that was transitioned to a virtual platform and participants' comfort engaging in and responding to incivility.

Method:

Face-to-face education was converted to a synchronous online event, supporting 75 nurses, nursing students, and other health care professionals in attendance. Activities consisted of cognitive rehearsal techniques, breakout rooms, simulation videos, group debriefs, and panel discussions delivered via Zoom and Mentimeter software.

Results:

Workplace Civility Index results were significantly different from pretest to post-test. Seventy-two percent of participants were not comfortable gossiping about others, but only 30% were comfortable responding to incivility.

Conclusion:

Promoting civility awareness through a virtual education platform using cognitive rehearsal techniques and reflection can provide support for current and future nurses.

[
J Contin Educ Nurs
. 2021;52(12):575–580.]
Postpandemic Nursing Education: Moving Forward With New Ideas
Authors: Valiga Theresa M.
Published: December 2021

Background:

Since March 2020, the world has faced many new challenges, and both faculty and students have needed to make many adjustments to the typical learning experience. Schools of nursing have reported on many innovative teaching strategies used during the coronavirus disease 2019 pandemic.

Method:

A reflective method was used to propose ideas related to postpandemic nursing education. Consideration was given to ways in which nursing education can be changed in response to lessons learned from the pandemic experience.

Results:

Most changes reported relate to the delivery of nursing education. Little has been published about the pandemic experience challenging educators to look more critically at the total academic experience and consider implementing changes that will enhance students' learning; support mental health; strengthen clinical partnerships; and help students internalize an identity as a nurse, scholar, and leader who can deal effectively with change and uncertainty.

Conclusion:

Nurse educators must think broadly about changes that can be made to achieve these goals.

[
J Nurs Educ
. 2021;60(12):680–685.]
Optimal control of an HIV model with a trilinear antibody growth function
Authors: Allali Karam , Harroudi Sanaa , Torres Delfim F. M.
Published: December 2021

We propose and study a new mathematical model of the human immunodeficiency virus (HIV). The main novelty is to consider that the antibody growth depends not only on the virus and on the antibodies concentration but also on the uninfected cells concentration. The model consists of five nonlinear differential equations describing the evolution of the uninfected cells, the infected ones, the free viruses, and the adaptive immunity. The adaptive immune response is represented by the cytotoxic T-lymphocytes (CTL) cells and the antibodies with the growth function supposed to be trilinear. The model includes two kinds of treatments. The objective of the first one is to reduce the number of infected cells, while the aim of the second is to block free viruses. Firstly, the positivity and the boundedness of solutions are established. After that, the local stability of the disease free steady state and the infection steady states are characterized. Next, an optimal control problem is posed and investigated. Finally, numerical simulations are performed in order to show the behavior of solutions and the effectiveness of the two incorporated treatments via an efficient optimal control strategy.
Hopf bifurcations of a Lengyel-Epstein model involving two discrete time delays
Authors: Bılazeroğlu Şeyma , Merdan Huseyin , Guerrini Luca
Published: December 2021

Hopf bifurcations of a Lengyel-Epstein model involving two discrete time delays are investigated. First, stability analysis of the model is given, and then the conditions on parameters at which the system has a Hopf bifurcation are determined. Second, bifurcation analysis is given by taking one of delay parameters as a bifurcation parameter while fixing the other in its stability interval to show the existence of Hopf bifurcations. The normal form theory and the center manifold reduction for functional differential equations have been utilized to determine some properties of the Hopf bifurcation including the direction and stability of bifurcating periodic solution. Finally, numerical simulations are performed to support theoretical results. Analytical results together with numerics present that time delay has a crucial role on the dynamical behavior of Chlorine Dioxide-Iodine-Malonic Acid (CIMA) reaction governed by a system of nonlinear differential equations. Delay causes oscillations in the reaction system. These results are compatible with those observed experimentally.
How Can Transactional Semantics Enhance the Commit Rate of Context-aware Service Composition in Advanced Pervasive Systems?
Authors: Ettazi Widad , Hafiddi Hatim , Nassar Mahmoud
Published: December 2021

Context-aware composition of services exhibiting transactional properties poses several challenges. A major challenge is the transactional behavior of candidate services which is subject to perpetual change while the composition is running. Compositions of services displaying transactional properties must be dynamically adapted at run time to cope with context fluctuations. By dynamic adaptation, we refer to the ability to alter the composition behavior in response to changes affecting its execution. We focus on changes impacting the successful commit rate of transactional service composition. This has led us to explore the trail of a flexible homeomorphism between alternative behaviors. We propose a behavioral adaptation approach that adjusts the behavior of transactional compositions of services in a proactive and transparent manner. This strategy is based on the Profiled Task Class concept. A service composition generator has also been developed for the performance evaluation of components implementing the behavioral adaptation strategy in order to identify its impact on the commit rate of CATS compositions.
The Role of Clinical Hypnosis & VR in Special Education
Authors: Drigas Athanasios , Mitsea Eleni , Skianis Charalabos
Published: December 2021

Clinical hypnosis is becoming increasingly recognized as a valuable clinical intervention for a wide range of psychological and medical problems. The current review paper seeks to determine the role of clinical hypnosis in learning difficulties, emotional or behavioral problems and physical disabilities. In addition, we co-examine the effectiveness of virtual/augmented reality hypnosis. Finally, we discuss the possible uses of clinical hypnosis within the educational settings. The results showed that hypnosis may hold the keys for new types of metacognitive strategies based on non-verbal pathways of effortless self-regulation.
Anti-Malarial Drug Resistance
Authors: Dwivedi Manish Kumar , Singh Prashant Kumar
Published: December 2021

Malaria is a life-threatening infectious disease caused by a protozoan parasite of the genus Plasmodium. It is transmitted through the bites of infected female Anopheles mosquitoes. The global burden is estimated to be around 219 million cases in 87 countries. Natural compounds have been used primarily in the traditional medicine for thousands of years. For the treatment of malaria, natural products were used until the development of synthetic drugs, and most of the currently available anti-malarial drugs have been derived based on the compounds from these traditional medicinal plants. The current chapter tries to briefly indicate the emerging resistance against anti-malarial drugs and to discuss the recent research on natural products that have been evaluated for anti-malarial activity. Rigorous evaluation of the efficacy and safety of traditional medicines is required along with identification of active constituents in order to develop new drugs with novel mechanisms of action.
Traditional Uses, Phytochemistry, and Pharmacological Properties of Zingiber officinale Essential Oil and Extracts
Authors: Ashokkumar Kaliyaperumal , Murugan Muthusamy , Dhanya M. K. , Sathyan Thiravidamani , Raj Surya , Mathews Nimisha
Published: December 2021

Ginger (Zingiber officinale) has been traditionally employed in south East Asia as well as India and China for treatment of nausea, asthma, fever, vomiting, cough, constipation, pain, arthritis, inflammation, etc. This chapter discusses the phytochemical composition and pharmacological studies of ginger extracts, ginger essential oil (GEO), and active bioactive constituents. The essential oil of fresh and dry ginger was ranged between 0.2% - 2.62% and 0.72% - 4.17% respectively. The bioactive constituent zingiberene, β-sesquiphellandrene, curcumene, β-bisabolene, β-farnesene, camphene, and gingerol and shogal are the major constituents in ginger extracts. These compounds are chief bioactive substances responsible for pharmacological activities such antioxidant, antidiabetic, anticancer, anticoagulant, antiradiation, anti-inflammatory, gastrointestinal, antimicrobial, cardiovascular, anti-obesity, and weight loss effects. Future research needs to investigate the suitable duration, maximum dosage of ginger, concerns of overdosage, and its side effects in animal models and humans.
Efficacy and Safety of CAM in Kidney Diseases
Authors: Tangkiatkumjai Mayuree , Kreepala Chatchai , Chen Li-Chia
Published: December 2021

The evidence of benefits and safety of complementary and alternative medicine for kidney diseases are still dubious to both practitioners and general public. Chinese herbal medicines are the main CAM in treating chronic kidney disease as an adjunctive therapy to conventional medicine. Several meta-analyses of randomised controlled trials assessing the efficacy of CHM reported that Astragalus and Cordyceps seem to have a beneficial effect on the kidneys. Acupuncture, yoga and aromatherapy may alleviate symptoms in patients with ESRD, such as pain, anxiety and pruritus. This evidence should be interpreted with caution due to several limitations of the RCTs of CAM, i.e., small sample sizes, unclear randomisation and blinding. Acute kidney injury is the common nephropathy caused by herbal and dietary supplements, e.g. aristolochic acid. Dietary supplements may induce uncontrolled hyperkalemia and hyperphosphatemia in patients with advanced CKD. Unregistered herbal products from India and China may be adulterated by conventional medicines and heavy metals, which could cause AKI.
Nutraceutical Properties of Important Weeds in India
Authors: Mishra Aakash , Chaudhari D. D. , Patel H. K. , Patel B. D.
Published: December 2021

The group of plants, apart from the forest trees, agricultural, horticultural crop and medicinal plants, certain weed plants also play important role to formulate the qualitative and quantitative food and health supplements. These plants may be very specific in producing certain compound to heal the specific ailment chronically or serve as a good nutritive food supplement. There are numbers of crop species have been fortified with multi-nutrients or with the particular nutrient supplements e.g. Rice, Wheat, Maize, Sweet Potato. Instead, weeds remained underutilized and un-exploited and also treated as unwanted species. The nutritive compounds available in these plants such as polyphenols and vitamins can be the extraction from different plant portion to formulate the fortified food or curing medicine. The weed species prevailing in the nature are one of the major sources of dietary and health supplements for humans and animals since past i.e. Amaranthus lividus, Chenopodium album and many more weed species. There is still much to explore the Indian ecologic components present in wild form of flora. Hence, this chapter will majorly contribute to highlight nutritive nutaceurtical and edible weeds prevailing in Indian ecosystems.
The Impact of Corporate Digital Responsibility (CDR) on Internal Stakeholders' Satisfaction in Hungarian Upscale Hotels
Authors: Kővári Edit , Saleh Mohamad , Steinbachné Hajmásy Gyöngyi
Published: December 2021

Digital transformation and artificial intelligence are considered among the most vital trending topics in the process of hospitality sector evolution. Many scholars found that digital transformation and artificial intelligence cause a massive shift in all aspects of the hospitality sector and digital technology application that impact the whole facet of internal and external stakeholders' lives. However, the adoption of digitalization and artificial intelligence is considered a strength. Corporate digital responsibility (CDR) is a strategy that enhances trust between the companies adopting digitalization and their primary stakeholders. Internal and external stakeholders' satisfaction develop contemporary social responsibility (CSR) challenges in the decision-making process in acquiring, analysing, implementing, and assessing for adopting digitalization in the hospitality sector. This chapter aims to give a literature review focusing on CDR and its relation analyses to hotel industry's internal stakeholders' satisfaction trough a Hungarian case study.
Electronic Word of Mouth Effects on Middle East Destination Overall Image and Behavioral Intention
Authors: Alfandi Ashraf Mohammad , Marco Valeri
Published: December 2021

This study investigated the relationship among e-WOM, overall destination image, and European tourist behavioral intention to revisit and recommend Jordan as a tourism destination. The study examined the mediating effect of destination overall image on the relationship between e-WOM and tourist behavioral intention. A total of 339 questionnaires were collected from European tourists who visited Jordan in 2018 through a self-administered questionnaire. Structural equation modeling (SEM) was used. The result of SEM identified that e-WOM has a positive influence on the overall destination image and on the tourist behavioral intention. The overall image positively influenced the tourist behavioral intention. Overall destination image partially mediates between e-WOM and behavioral intention, and thereby, the positive impact of e-WOM on behavioral intention could be aggravated through the mediating effect of destination overall image. The findings have implications on the tourism industry, especially for key players in the Jordanian tourism board and travel companies.
Literacy Strategies for the d/DHH/EL Population
Authors: Turner Molly , Gardiner-Walsh Stephanie J.
Published: December 2021

In education today, there is an increasing population of individuals who are d/Deaf/Hard of Hearing and English Learners (d/DHH/ELs). This population of students need innovative teaching strategies to achieve optimal outcomes. Schools are challenged with providing education to these students, and there are many barriers to overcome. Teachers receive little to no education on how to teach this combined population of learners. Knowing this, the chapter will discuss characteristics of the population, literacy and language acquisition, barriers, and strategies to promote literacy development in the d/DHH/EL population.
African American Parents' Perceptions of Early Literacy Strategies
Authors: Smith Zanthia Yvette
Published: December 2021

Few research-based family studies have focused specifically on the perceptions of African American hearing parents' use of home literacy strategies. This study was conducted with a small group of African American families, taking into account family's individual literacy needs (African American hearing families with deaf/hard of hearing [DHH] children), African-American culture and language, emergent literacy research, American Sign Language (ASL), and parent-child book reading strategies. The purpose of this study was to document parental perception of the literacy process, while establishing opportunities for parents to practice under the guidance of mentors and within the home environment. Recordings documented parental progress and their comments about the reading process. Field notes were generated from the mentors' discussions with parents. This exploratory case study identified changes in parental perception of communication and literacy development during a nine-week intervention and records their reactions to those support strategies.
Examining Fatigue for Students Who Are Deaf or Hard of Hearing Through Universal Design for Learning
Authors: Rohatyn-Martin Natalia K. , Hayward Denyse V.
Published: December 2021

In current educational contexts, Deaf or hard of hearing (D/HH) students are being educated in inclusive classrooms. However, academic and social outcomes for these bilingual or multilingual students remain highly variable indicating that meeting the needs for students who are D/HH continues to be challenging for many educators. Many D/HH students are reporting high levels of fatigue throughout their school day. To ensure the diverse cultural and linguistic backgrounds of students are being met, a more flexible approach needs to be considered to address barriers described by D/HH students. As such, the authors use the Universal Design for Learning framework to discuss fatigue for students who are D/HH in inclusive contexts, particularly those who are bilingual/multilingual.
An Alternative to Socio-Economic Injustice
Authors: Seigel Susan E. , Flickinger Debby E.
Published: December 2021

Individuals have responded with a variety of responses to crises such as war, natural disasters, famine, and pandemics. These are times when people have pulled together to overcome these challenges, or sometimes have divided themselves ideologically, politically, and behaviorally. This chapter addresses some of those characteristics within the United States affecting national and global relationships in the 21st century. The authors support the perception that there is a need for behavioral and cultural change—caring. Specifically, the authors propose an alternative paradigm: the development and sustainability of a “culture of care” as an interdisciplinary approach for national behaviors and international collaboration. The work of two American scholars, Nel Noddings and Jean Watson, center on the importance of the philosophy of care, caring theory, and practice in education and nursing. Going forward to more international crises such as climate change, the COVID-19 pandemic, and poverty and hunger, the authors look to a more equitable and collaborative means to address these problems.
Internationalization in Times of Uncertainty
Authors: Thees Hannes
Published: December 2021

This chapter aims to explore the uncertainties that the COVID-19 pandemic induced in internationalization. In this regard, the COVID-19 pandemic challenges companies worldwide as global value chains were interrupted and business models were contested. The theoretical background describes the internationalization processes and the specific role of foreign direct investments (FDI), but also the basics of uncertainty in doing business. Because of the scope of internationalization and the peculiarities of the COVID-19 pandemic, a descriptive analysis of secondary data from global databases was conducted. This includes macroeconomic data and also global research reports. With a focus on European-Asian relations, the results reveal an interruption in the flows of goods and services in Eurasia, but more importantly, also in FDI. Further on, there is a correlation between uncertainty and FDI flows. Finally, this chapter discusses future directions in internationalization, including resilience, regionalization, and the rise of China in global economics.
Perspectives, Strategies, and Propositions for Cultivating Inclusive Educational Environments
Authors: Vasquez Ananí M.
Published: December 2021

This chapter activates a rethinking of educational system deep structures and proposes perspectives, strategies, and interactive propositional tasks for cultivating inclusive educational environments. Neurotypicality in deep structures has been used to bolster ableism and oppression, impeding the development of inclusion in schools and supporting the ongoing exclusion of intersectional, neurodiverse individuals. Inclusive education could be reimagined using a neurodiversity perspective, promoting strategies for critical analysis of deep structures and strategies for creative learning, and engaging with experimental propositions for practice that invite educators to engage with creative learning concepts. Creative learning, as personal and collaborative meaning-making, also extends beyond student learning to professional learning and educational research. Readers are asked to engage with and beyond the text in critical reflection toward purposeful action.
Learning to Teach and Teaching to Learn
Authors: Liu Kimy , Bukko Debra
Published: December 2021

Preservice teachers are developing their professional identity while honing their teaching skills. Without transformative learning experience, preservice teachers will teach students the ways they were taught. They can have exclusive and deficit mindsets about students with disabilities (SWDs), many of whom are also English learners. Exclusive and deficit mindsets can lead to two teaching approaches: One is to treat SWDs as inferior to their typical peers. The other is to insist on standardized instruction for the sake of equality. In this chapter, the authors, as the teacher preparation faculty, confronted this challenge by engineering a transformative learning experience to liberate preservice teachers from the deficit mindsets about teaching students with disabilities.
Factors Affecting Rice Farmers’ Choice of Formal Seed
Authors: Ilangathilaka K.A.G. , Rupasena L.P. , Fernando S.
Published: December 2021

Stagnation of rice productivity is a major issue in Sri Lanka because expansion of land extent is not possible due to reach of its maximum level. Moreover, it is urgently need to release some rice lands for cultivation of non-rice crops to meet their demand. Among other factor seed quality greatly influences on rice productivity. Despite the seeds supplied through formal sources such as government and private seed producers are certified for their quality, use of uncertified seeds sourced from informal sources such as farmer-saved seeds which are not certified has been a major problem resulting low productivity. Understanding how farmers choose between formal and informal seed sources is important to promote the use of certified quality seeds among farmers to enhance the productivity. Therefore, this study aims to identify the factors that determine the choice of formal seeds. A total of randomly selected 59 rice farmers in Nachchaduwa settlement of Anuradhapura district was interviewed using a pretested questionnaire. Tabular analysis and binary logistic regression were used to analyze the data. The tabular analysis showed that a 43% of the sampled farmers used informal seeds due to the unavailability of formal seeds in the farming communities. The price of seeds (p<0.05) and the distance to the source (p<0.05) from the farmer's dwelling have significantly and positively affected the choice of formal seeds over informal seeds. Farmers are more likely to travel far in searching and pay more for formal seeds. This type of behavior reflects the quality consciousness of farmers. To improve the uptake the access to formal rice seeds needs to be increased. Since private or government suppliers of formal seeds are less available in the settlement, individuals and farmer organizations should be incentivized to produce certified formal seeds.