bluuebunny/crossref_metadata_2025 huggingface dataset:
When Is a Solution Not a Solution? Wicked Problems, Hybrid Solutions, and the Rhetoric of Civic Entrepreneurship
Authors: Gerding Jeffrey M. , Vealey Kyle P.
Published: March 2017

This article examines the ongoing development of +POOL, a recreational pool, filtration system, and floating laboratory, to better understand the rhetorical work involved in civic entrepreneurship. The authors consider how the overall development of +POOL as an entrepreneurial venture might help expand the inventive possibilities for civic entrepreneurs coming to grips with wicked problems today. The study offers a look into the rhetorical work of civic entrepreneurship by examining the way +POOL develops a hybrid solution, which recognizes and foregrounds the notion that wicked problems, such as the pollution of the East River, can never be fully understood or known at any one moment. Hybrid solutions, then, offer stable outcomes for civic entrepreneurial ventures that are dynamic enough to continually adapt to the shifting and evolving contours of a wicked problem.
Hunter–Prey Discourse: A Critical Discourse Analysis of the Online Posts of Men Who Buy Sex
Authors: Bounds Dawn , Delaney Kathleen R. , Julion Wrenetha
Published: March 2017

BACKGROUND: The Internet has emerged as a major expediter of the commercial sex (CS) industry. While use of web-based CS industry sites is brisk, the full extent of their impact remains unclear particularly how they influence users’ views of the CS industry. OBJECTIVE: This research study sought to uncover the nuances of buyers’ interactions on an online CS website. DESIGN: Six hundred sixty-six online posts from 363 unique members were collected and analyzed using critical discourse analysis. RESULTS: Via the use of language and dialogue, particular ways of thinking about and talking about buying sex are normalized and reinforced. Evident within these discursive patterns are mechanisms by which assumptions are forwarded, perceptions shaped, and authority established. CONCLUSIONS: Information about how CS industry websites establish beliefs, relationships, and practices among its users may increase understanding of how the CS industry seeks to gain acceptance in the American culture and normalize its activities.
What was the ‘Kurdish opening’ all about? A qualitative text analysis of parliamentary group speeches in Turkey
Authors: Öney Berna , Selck Torsten J.
Published: March 2017

This study explores the use of four discourses – socio-economic, relative deprivation, pro-Islamist and terrorism oriented – used by political parties in Turkey to address the Kurdish issue and the resulting political party strategies during the Kurdish opening in Turkey. Although the factors that influence the Kurdish issue have drawn attention, no research has analysed Turkish political parties’ perspectives on the Kurdish issue in primary political documents. By examining 188 parliamentary group speeches delivered during the Kurdish opening process with qualitative text analysis, this study reveals that the mainstream parties in the Turkish Parliament employ socio-economic, relative deprivation and regional terrorism approaches, while the ethnic parties use either regional terrorism and pro-Islamist approaches or the relative deprivation approach. Due to the overlap in their discourses, the mainstream parties have developed a new strategy: compartmentalization of the ethnic issue by creating sub-ethnic categories. This research contributes to revealing political parties’ approaches to the Kurdish question and their strategies for mobilizing the ethnic median voter.
Acute basilar artery occlusion: Endovascular Interventions versus Standard Medical Treatment (BEST) Trial—Design and protocol for a randomized, controlled, multicenter study
Authors: Liu Xinfeng , Xu Gelin , Liu Yuxiu , Zhu Wusheng , Ma Minmin , Xiong Yunyun , Zi Wenjie , Dai Qiliang , Leung Thomas , Yan Bernard , Davis Stephen , Liebeskind David S , Pereira Vítor M , Nogueira Raul G
Published: March 2017

Rationale

Endovascular treatment plus standard medical therapy is superior to standard medical therapy alone for acute anterior proximal intracranial large artery occlusion strokes. The benefit of endovascular treatment in acute ischemic stroke caused by basilar artery occlusion remains unproven.

Aim

This study compares the safety and efficacy of endovascular treatment plus standard medical therapy versus standard medical therapy alone in acute ischemic stroke due to basilar artery occlusion.

Design

The study is a multicenter randomized control trial with blinded outcome assessment. A projected total 344 subjects with acute basilar arterial occlusion within 8 h of estimated occlusion time will be enrolled over three years in China. Patients will be assigned to endovascular treatment plus standard medical therapy and standard medical therapy alone group in 1:1 ratio for study centers.

Study outcomes

The primary outcome measure is a favorable functional outcome, defined as a modified Rankin Score of 0–3 at 90 days. The primary safety measure is mortality at 90 days.

Trial registration

ClinicalTrials.gov (NCT 02441556).

The BEST trial will provide valuable insights into the safety and efficacy of endovascular treatment for acute ischemic stroke patients with basilar artery occlusion.
Unclear-onset intracerebral hemorrhage: Clinical characteristics, hematoma features, and outcomes
Authors: Inoue Yasuteru , Miyashita Fumio , Koga Masatoshi , Minematsu Kazuo , Toyoda Kazunori
Published: March 2017

Background and purpose

Although unclear-onset ischemic stroke, including wake-up ischemic stroke, is drawing attention as a potential target for reperfusion therapy, acute unclear-onset intracerebral hemorrhage has been understudied. Clinical characteristics, hematoma features, and outcomes of patients who developed intracerebral hemorrhage during sleep or those with intracerebral hemorrhage who were unconscious when witnessed were determined.

Methods

Consecutive intracerebral hemorrhage patients admitted within 24 hours after onset or last-known normal time were classified into clear-onset intracerebral hemorrhage and unclear-onset intracerebral hemorrhage groups. Outcomes included initial hematoma volume, initial National Institutes of Health Stroke Scale score, hematoma growth on 24-hour follow-up computed tomography, and vital and functional prognoses at 30 days.

Results

Of 377 studied patients (122 women, 69 ± 11 years old), 147 (39.0%) had unclear-onset intracerebral hemorrhage. Patients with unclear-onset intracerebral hemorrhage had larger hematoma volumes (p = 0.044) and higher National Institutes of Health Stroke Scale scores (p < 0.001) than those with clear-onset intracerebral hemorrhage after multivariable adjustment for risk factors and comorbidities. Hematoma growth was similarly common between the two groups (p = 0.176). There were fewer patients with modified Rankin Scale (mRS) scores of 0–2 (p = 0.033) and more patients with mRS scores of 5–6 (p = 0.009) and with fatal outcomes (p = 0.049) in unclear-onset intracerebral hemorrhage group compared with clear-onset intracerebral hemorrhage as crude values, but not after adjustment.

Conclusions

Patients with unclear-onset intracerebral hemorrhage presented with larger hematomas and higher National Institutes of Health Stroke Scale scores at emergent visits than those with clear-onset intracerebral hemorrhage, independent of underlying characteristics. Unclear-onset intracerebral hemorrhage patients showed poorer 30-day vital and functional outcomes than clear-onset intracerebral hemorrhage patients; these differences seem to be mainly due to initial hematoma volumes and National Institutes of Health Stroke Scale scores.
The Response of Bats (Mammalia: Chiroptera) to Habitat Modification in a Neotropical Savannah
Authors: de Oliveira Hernani F. M. , de Camargo Nícholas F. , Gager Yann , Aguiar Ludmilla M. S.
Published: March 2017

The Brazilian savanna (Cerrado) is a biodiversity hotspot with high deforestation rates that lead to extensive habitat changes, especially around protected areas (PAs). In our study, we analyzed how bats are affected by habitat changes comparing assemblages inside and outside Cerrado PAs. We compared diversity patterns of bats in relation to species composition, number of captured bats, as well as body condition and reproductive condition in cerrado sensu stricto (s.s.) and gallery forests. From September 2007 to June 2008, we captured 495 bats belonging to 25 species, 4 families, and 6 foraging guilds. When comparing captured bats inside and outside PAs, we found different patterns for both habitats, but with no differences in species richness for both habitats in relation to habitat perturbation. In relation to the degree of preservation, bat assemblages tend to be dissimilar between cerrado s.s. and similar between gallery forests. Besides that, in cerrados s.s., bats are less captured, or negatively affected, by habitat disturbance outside PAs; while in gallery forests, they are positively affected. Likewise, some bat species in gallery forests present higher body condition and more reproductive individuals outside PAs. Finally, we suggest that the intense habitat change in cerrado s.s. does cause negative effects on bats, while the positive effects found in degraded gallery forests may be due to the higher resource availability derived mainly from pioneer plants. Therefore, the presence of both nectarivorous bats in cerrado s.s. and frugivorous bats in gallery forests can be considered good indicators for habitat disturbance.
Neuroleptic malignant syndrome following catatonia: Vigilance is the price of antipsychotic prescription
Authors: Reilly Thomas J , Cross Sean , Taylor David M , Haslam Richard , Tomlin Sophie C , Gaastra Benjamin
Published: March 2017

Objectives:

To describe a case of neuroleptic malignant syndrome following antipsychotic treatment of catatonia, highlighting the potentially serious complications of this rare adverse drug reaction.

Methods:

We present a case report of a patient who developed this syndrome with various sequelae.

Results:

The patient developed neuroleptic after being treated with lorazepam and olanzapine for catatonia. He subsequently developed the complications of rhabdomyolysis, acute kidney injury, pulmonary embolism, urinary retention and ileus. He received high-dose lorazepam, anticoagulation and intravenous fluids. Antipsychotic medication in the form of haloperidol was reinstated with no adverse effect, and he went on to make a full recovery.

Conclusions:

This case illustrates the potential life-threatening complications of neuroleptic malignant syndrome and the need for a low index of clinical suspicion. It also highlights the lack of evidence for treatment of catatonia, including the use of antipsychotics.
Online dynamic pricing and consumer-perceived ethicality: Synthesis and future research
Authors: Ayadi Nawel , Paraschiv Corina , Rousset Xavier
Published: March 2017

In the era of Big Data, online retailers’ pricing strategies are evolving towards an online dynamic pricing system, which consists in frequent modifications of the prices of goods and services in order to maximize sales and profits. This strategy raises important ethical questions, because consumers end up paying different prices for the same product. The aim of our article is to examine, from the consumer’s point of view, the ethical issues raised by online dynamic pricing. We propose a conceptual framework and a future research agenda with regard to consumers’ perceived ethicality about this strategy.
Race, Juvenile Transfer, and Sentencing Preferences: Findings From a Randomized Experiment
Authors: Lehmann Peter S. , Pickett Justin T. , Ryon Stephanie Bontrager , Kosloski Anna E.
Published: March 2017

In light of the expansion of punitive “get tough” policies for juvenile offenders, some researchers have uncovered evidence that juveniles who are waived to the adult court receive more severe sanctions than retained juveniles. Theoretically, the transfer status of delinquents may serve as a cognitive heuristic in criminal justice system (CJS) actors’ “focal concern” judgments. Understood through this framework, transfer status may signify to CJS workers, and especially Whites, that a juvenile offender is especially dangerous or blameworthy, thereby justifying harsher punishments. To examine these relationships, two experimental vignettes were embedded in a national survey of CJS workers in which the transfer status of the offender was randomized. Analyses reveal that respondents did not prefer harsher sentences for the transferred violent male delinquent, but they did recommend significantly harsher sentences for the transferred nonviolent female delinquent. White respondents, however, were especially punitive in their sentencing preferences for the transferred violent male delinquent. The findings are partially consistent with the theoretical expectation that transfer status functions as a heuristic in CJS actors’ assessments of juvenile offenders. The results also suggest that White CJS workers may racially typify violent youth who have been transferred to adult court.
Effective Medicinal Plant in Cancer Treatment, Part 2: Review Study
Authors: Kooti Wesam , Servatyari Karo , Behzadifar Masoud , Asadi-Samani Majid , Sadeghi Fatemeh , Nouri Bijan , Zare Marzouni Hadi
Published: March 2017

Cancer is the second cause of death after cardiovascular diseases. With due attention to rapid progress in the phytochemical study of plants, they are becoming popular because of their anticancer effects. The aim of this study was to investigate the effective medicinal plants in the treatment of cancer and study their mechanism of action. In order to gather information the keywords “traditional medicine,” “plant compounds,” “medicinal plant,” “medicinal herb,” “toxicity,” “anticancer effect,” “cell line,” and “treatment” were searched in international databases such as ScienceDirect, PubMed, and Scopus and national databases such as Magiran, Sid, and Iranmedex, and a total of 228 articles were collected. In this phase, 49 nonrelevant articles were excluded. Enhancement P53 protein expression, reducing the expression of proteins P27, P21, NFκB expression and induction of apoptosis, inhibition of the PI3K/Akt pathway, and reduction of the level of acid phosphatase and lipid peroxidation are the most effective mechanisms of herbal plants that can inhibit cell cycle and proliferation. Common treatments such as radiotherapy and chemotherapy can cause some complications. According to results of this study, herbal extracts have antioxidant compounds that can induce apoptosis and inhibit cell proliferation by the investigated mechanisms.
Anatomic and Biomechanical Comparison of the Classic and Congruent-Arc Techniques of the Latarjet Procedure
Authors: Montgomery Scott R. , Katthagen Jan Christoph , Mikula Jacob D. , Marchetti Daniel C. , Tahal Dimitri S. , Dornan Grant , Dahl Kimi , Brady Alex , Turnbull Travis L. , Millett Peter J.
Published: March 2017

Objectives:

The Latarjet procedure is commonly performed using either the classic (standing) or the congruent-arc (lying) technique. There are potential clinical advantages and disadvantages of each technique. However, the anatomic and biomechanical effects, benefits, and limitations of each technique are unknown. The purpose of this study was to compare the anatomy and biomechanical strength of fixation between the two techniques.

Methods:

A biomechanical cadaver study was performed with 20 pairs of male and female shoulders (n=40). One of each pair of shoulders was randomly assigned to receive the classic or congruent-arc technique. Coracoid and glenoid anatomic measurements were collected prior to biomechanical testing. A pull force was applied through the conjoined tendon to replicate forces experienced by the coracoid graft in the early post-operative period, and the failure load was determined for each specimen ( Figure 1 ). [Figure: see text]

Results:

The mean surface area available for fixation in the classic technique was 263.3 mm2 compared to 177.0 mm2 in the congruent-arc group (p<0.001). In the classic group, 36% of the glenoid width was re-created, and 50% was re-created in the congruent-arc group (p<0.001). The congruent-arc technique resulted in a significantly lower (p=0.005) mean failure load (238.9 ± 91.2 N) compared to the classic technique (303.0 ± 114 N). Failure load was significantly higher in males (p=0.037); male specimens had a mean failure load of 343.9 ± 122.2 N for the classic technique and 289.4 ± 73.0 N for the congruent-arc technique, and females had a mean failure load of 266.1 ± 97.7 and 193.5 ± 84.0 N, respectively ( Figure 2 ). [Figure: see text]

Conclusion:

In this biomechanical model, the classic technique of the Latarjet procedure provided a greater surface area for healing to the glenoid and greater biomechanical strength of fixation when compared to the congruent-arc technique. The congruent-arc technique allowed restoration of a larger glenoid defect.
LA TRANSICIÓN DE RELIME AL CONTEXTO EDITORIAL DIGITAL
Authors: Montiel-Espinosa Gisela
Published: March 2017

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How to run a children's day
Authors: Bissett Gaby
Published: March 2017

Michelle Reid reveals her top tips to educating and engaging younger patients. By Gaby Bissett
CPD – quality or quantity?
Authors: Wake Charlotte
Published: March 2017

Continuing Professional Development – what does it mean to you? Charlotte Wake goes on the hunt for suitable sources and discovers some good practice along the way
Thinking implant dentistry? Think training
Authors: Allan Kasia
Published: March 2017

Kasia Allan explains why dental nurses should look at training in implant dentistry
Do you wear it well?
Authors: Cash Charlotte
Published: March 2017

All members of staff must take a sensible and safe approach to their dress and appearance, cleanliness and personal hygiene. Charlotte Cash explains why
Prevention of periprosthetic joint infection
Authors: Parvizi J. , Shohat N. , Gehrke T.
Published: March 2017

The World Health Organization (WHO) and the Centre for Disease Control and Prevention (CDC) recently published guidelines for the prevention of surgical site infection. The WHO guidelines, if implemented worldwide, could have an immense impact on our practices and those of the CDC have implications for healthcare policy in the United States.

Our aim was to review the strategies for prevention of periprosthetic joint infection in light of these and other recent guidelines.

Cite this article: Bone Joint J 2017;99-B(4 Supple B):3–10.
Posterior condylar offset is an independent predictor of functional outcome after revision total knee arthroplasty
Authors: Clement N. D. , MacDonald D. J. , Hamilton D. F. , Burnett R.
Published: March 2017

Objectives

Preservation of posterior condylar offset (PCO) has been shown to correlate with improved functional results after primary total knee arthroplasty (TKA). Whether this is also the case for revision TKA, remains unknown. The aim of this study was to assess the independent effect of PCO on early functional outcome after revision TKA.

Methods

A total of 107 consecutive aseptic revision TKAs were performed by a single surgeon during an eight-year period. The mean age was 69.4 years (39 to 85) and there were 59 female patients and 48 male patients. The Oxford Knee Score (OKS) and Short-form (SF)-12 score were assessed pre-operatively and one year post-operatively. Patient satisfaction was also assessed at one year. Joint line and PCO were assessed radiographically at one year.

Results

There was a significant improvement in the OKS (10.6 points, 95% confidence interval (CI) 8.8 to 12.3) and the SF-12 physical component score (5.9, 95% CI 4.1 to 7.8). PCO directly correlated with change in OKS (p < 0.001). Linear regression analysis confirmed the independent effect of PCO on the OKS (p < 0.001) and the SF-12 physical score (p = 0.02). The overall rate of satisfaction was 85% and on logistic regression analysis improvement in the OKS (p = 0.002) was a significant predictor of patient satisfaction, which is related to PCO; although this was not independently associated with satisfaction.

Conclusion

Preservation of PCO should be a major consideration when undertaking revision TKA. The option of increasing PCO to balance the flexion gap while maintaining the joint line should be assessed intra-operatively. Cite this article: N. D. Clement, D. J. MacDonald, D. F. Hamilton, R. Burnett. Posterior condylar offset is an independent predictor of functional outcome after revision total knee arthroplasty. Bone Joint Res 2017;6:172–178. DOI: 10.1302/2046-3758.63.BJR-2015-0021.R1.
Silencing of translation initiation factor eIF3b promotes apoptosis in osteosarcoma cells
Authors: Choi Y. J. , Lee Y. S. , Lee H. W. , Shim D. M. , Seo S. W.
Published: March 2017

Objectives

Eukaryotic translation initiation factor 3 (eIF3) is a multi-subunit complex that plays a critical role in translation initiation. Expression levels of eIF3 subunits are elevated or decreased in various cancers, suggesting a role for eIF3 in tumorigenesis. Recent studies have shown that the expression of the eIF3b subunit is elevated in bladder and prostate cancer, and eIF3b silencing inhibited glioblastoma growth and induced cellular apoptosis. In this study, we investigated the role of eIF3b in the survival of osteosarcoma cells.

Methods

To investigate the effect of eIF3b on cell viability and apoptosis in osteosarcoma cells, we first examined the silencing effect of eIF3b in U2OS cells. Cell viability and apoptosis were examined by the Cell Counting Kit-8 (CCK-8) assay and Western blot, respectively. We also performed gene profiling to identify genes affected by eIF3b silencing. Finally, the effect of eIF3b on cell viability and apoptosis was confirmed in multiple osteosarcoma cell lines.

Results

eIF3b silencing decreased cell viability and induced apoptosis in U2OS cells, and by using gene profiling we discovered that eIF3b silencing also resulted in the upregulation of tumour necrosis factor receptor superfamily member 21 (TNFRSF21). We found that TNFRSF21 overexpression induced cell death in U2OS cells, and we confirmed that eIF3b silencing completely suppressed cell growth in multiple osteosarcoma cell lines. However, eIF3b silencing failed to suppress cell growth completely in normal fibroblast cells.

Conclusion

Our data led us to conclude that eIF3b may be required for osteosarcoma cell proliferation by regulating TNFRSF21 expression. Cite this article: Y. J. Choi, Y. S. Lee, H. W. Lee, D. M. Shim, S. W. Seo. Silencing of translation initiation factor eIF3b promotes apoptosis in osteosarcoma cells. Bone Joint Res 2017;6:186–193. DOI: 10.1302/2046-3758.63.BJR-2016-0151.R2.
Supporting working carers’ job continuation in Japan: prolonged care at home in the most aged society
Authors: Ikeda Shingou
Published: March 2017

This article concerns new policy challenges relevant to companies in supporting working carers of older people to retain their jobs in Japan. Although long-term leave and flexible working measures have been reformed to address long-term in-home care, the results of new data analysis imply that the effectiveness of support measures differs according to the length of the period of care provided at home. Long-term leave and reducing working hours are effective if the period in which care is provided is relatively short, but when care at home lasts longer, flexibility in the working schedule is crucial. The results also signal the importance of addressing the health of working carers as a new challenge that arises regardless of the length of care at home.
General and proximal associations between unpaid eldercare, time constraints and subjective well-being
Authors: Lam Jack , Garcia-Roman Joan
Published: March 2017

Population ageing requires understanding the implications of eldercare. Using American Time Use Surveys, we find that caregivers spend less time on personal care and social activities/sports, and more time on housework, than individuals who do not provide any eldercare. They also report higher stress and lower happiness. In addition, caregivers may not provide care every day, but on days when they do, they also spend more time on housework and less on paid work, and report higher levels of sadness than on days when they do not provide care. Regular caregivers experience worse wellbeing than non-caregivers, but also experience additional strain on days when they provide care.
Occurrence of dental involvement in victims of violence
Authors: Barbieri Ana Amélia , França Cristiano de , Naressi Suely Carvalho Mutti , Tosello Darcy de Oliveira , Daruge Júnior Eduardo
Published: March 2017

Objective - To verify the occurrence of dental involvement described in medical examination reports on facial trauma resulting from interpersonal violence. Material and methods: an observational, analytical, and retrospective study that verified the dental involvement described in all the medical examination reports involving facial trauma, arising from interpersonal violence, issued by the Instituto Médico Legal - IML (Forensic Medicine Institute) of Taubaté, in São Paulo state, in a period of 24 months, considering gender and age group. Results: Of the 12,184 reports issued during the period studied, 1,971 (16.17%) described facial injuries resulting from aggression, and of these, 5.07% contained reports of dental involvement. The most frequent injury was a fracture (2.99%), in the age range between 16 and 24 years (31.42%), and the gender, male (56%).  Conclusion: The facial injuries resulting from interpersonal violence in the analyzed period amounted to 16.17% of the total of cases, with 5.07% of these presenting reports of dental involvement. KEYWORDSForensic Dentistry; Injuries; Violence.
Influence of Different Obturation Systems on the Fracture Resistance of Endodontically Treated Roots
Authors: Doumani Mazen , Abdulrab Saleem , Samran Abdulaziz , Doumani Ahmed , Layous Kinda , Özcan Mutlu
Published: March 2017

Objective: This study aimed to compare the fracture resistance of endodontically treated roots filled by different obturation systems. Material and methods: Ninety-six upper central incisors were used and decoronated, retaining 12 mm of the roots. On the basis of obturation systems, the roots were divided into 4 groups (n=24): Group1 (COGR): control group (unprepared, unfilled), Group 2 (AVGR): ActiV GP points/ActiV GP sealer, Group3 (GPGR): Gutta percha points/AH plus sealer, and Group4 (GAGR): Gutta percha points/ActiV GP sealer. The last three groups were obturated with the single cone technique. The roots were then stored in 100% relative humidity at 37 °C for 2 weeks. A vertical compressive force was exerted with a universal testing machine until a fracture occurred. Data were statistically analyzed with one-way ANOVA. Results: Mean (SD) failure loads for groups ranged from 920.51 ± 210.37 to 1113.44 ± 489.42 N. The fracture resistance between the different study groups indicated no statistical difference. Conclusions: ActiV GP system did not exert a significant effect on the fracture resistance of endodontically treated teeth.
Composite resin repairs: What is the most effective protocol?
Authors: Andrade Alessandra Pereira , Shimaoka Angela Mayumi , Carvalho Rubens Corte Real de
Published: March 2017

Objective: The objective of this study was to evaluate the combination effect of surface treatments and bonding agents on bond strength of repairs on aged composite resin. Materials and Methods: One hundred twenty microhybrid composite units (Filtek Z250) aged in distilled at 37ºC water for six months were submitted to different surface treatment prior to resin repairs. Ten specimens were randomly divided into 12 groups: non-treated/no bonding agent (negative control), sandblasting /no bonding agent, silane/no bonding agent, non-treated/ etch-and-rinse; non-treated/one-step self-etch; non-treated/ two-step self-etch; sandblasting/etch-and-rinse; sandblasting/one-step self-etch; sandblasting/two-step self-etch; silane coupling agent/etch-and-rinse; silane coupling agent/ one-step self-etch; silane coupling agent/two-step self-etch. Microshear testing was performed to bond strength assessment. Results: Two-way ANOVA and Tukey’s test (?=0.05) demonstrated significant difference between the surface treatments and adhesive systems. Only no treated surface/etch-and-rinse group showed lower bond strength values when compared to other groups. Conclusion: The considered surface treatments were capable to increase the effectiveness of the repair in composite resin when using the adhesive etch-and-rinse.
A variety of exact analytical solutions of extended shallow water wave equations via improved (Gâ€™/G) -expansion method
Authors: Hawlader Faisal , Kumar Dipankar
Published: March 2017

In this present work, we have established exact solutions for (2+1) and (3+1) dimensional extended shallow-water wave equations in-volving parameters by applying the improved (Gâ€™/G) -expansion method. Abundant traveling wave solutions with arbitrary parameter are successfully obtained by this method, and these wave solutions are expressed in terms of hyperbolic, trigonometric, and rational functions. The improved (Gâ€™/G) -expansion method is simple and powerful mathematical technique for constructing traveling wave, solitary wave, and periodic wave solutions of the nonlinear evaluation equations which arise from application in engineering and any other applied sciences. We also present the 3D graphical description of the obtained solutions for different cases with the aid of MAPLE 17.
SPATIAL TRANSFORMATION OF SURAKARTA’S PERIPHERAL RURAL VILLAGES UNDER IN-SITU URBANIZATION PHENOMENON : THE CASE OF GENTAN VILLAGE
Authors: Purnamasari Lia Sparingga , Yudana Galing , Rini Erma Fitria
Published: March 2017

Surakarta is one of the rapidly growing Indonesian cities. The pressure towards its peripheral area results in ‘in-situ urbanization’ phenomenon of its rural village surroundings. Gentan is one of Surakarta adjacent rural villages that has been undergoing rapid spatial transformation from rural to urban settlement in the last 20 years (1995-2016). This research aims to clarify the spatial transformation in Gentan village through examinations of its spatial elements on higher resolution level; (1) transformation of its street network connectivity, (2) land use pattern, (3) building density, and (4) public facilities and accessibility. Secondary data from satellite imagery and government institution and primary data from field survey were used in this research as sources. From Gentan’s spatial elements observations, this research concluded that this village was transforming into urban settlements by its spatial elements characteristics. Furthermore, this research provides interesting findings by its analysis on the neighborhood level that while Gentan was transforming into urban settlement, its internal connectivity was decreasing, residential uses dominated its land use, the village was dominated by the formal settlement, and the reach distance of its public facilities fluctuated across the time.
Cell proliferation assay – method optimisation for in vivo labeling of DNA in the rat forestomach
Authors: Joksić Gordana , Mićić Mileva , Filipović Jelena , Drakulić Dunja , Stanojlović Miloš , Čalija Bojan , Valenta Šobot Ana , Demajo Miroslav , Nilsson Robert
Published: March 2017

The study of cell proliferation is a useful tool in the fields of toxicology, pathophysiology and pharmacology. Cell proliferation and its degree can be evaluated using 5-bromo-2′-deoxyuridine which is incorporated into the newly synthesized DNA. The aim of this study was the optimization of subcutaneous application of 5-bromo-2′-deoxyuridine implantation for continuous and persistent marking of proliferating cells in the rat forestomach. 3-tert-Butyl-4-hydroxyanisole was used as the agent that ensures cell proliferation. In order to determine the optimal dose for proliferating cells labeling, 5-bromo-2′-deoxyuridine doses of 50 mg, 100 mg, 200 mg or 350 mg were implemented 2 days prior to sacrifice by flat-faced cylindrical matrices. Immunohistochemical analysis using 5-bromo-2′-deoxyuridine in situ detection kit was performed for the detection of 5-bromo-2′-deoxyuridine labeled cells. The results showed that for adult rats, the optimum 5-bromo-2′-deoxyuridine dose is 200 mg per animal for subcutaneous application. The here described manner of 5-bromo-2′-deoxyuridine in vivo labeling provides a simple, efficient, and reliable method for cell labeling, and at the same minimizes stress to animals.
Renal vasography in mink (Mustela vison)
Authors: Mrvić Verica , Avdić Rizah , Hadžiomerović Nedžad , Tandir Faruk , Prokić Branislav , Tomašević Ratko , Prokić Bogomir Bolka
Published: March 2017

This paper presents the results of the research on renal blood vessels of the mink. The main goal of this research is to provide a unique insight in renal vessel constellation and thereby contributes to the amount and quality of the available data on the cardiovascular system of the mink, since the data found in the available literature regarding this specific field is rather poorly documented. Blood vessels of the mink kidney were studied by dissection and corrosion injection technique. The renal artery and its branches, and the lobar, interlobar and interlobular arteries are terminal arteries and they do not anastomose between each other. The arterial system is characterized by two independent vascular areas, supplied by the dorsal and ventral lobar artery. Lobar arteries divide the kidney horizontally into a dorsal and ventral half, while lobar veins divide it vertically into the cranial and caudal half. The renal vein is formed from the cranial and caudal lobar vein. The obtained results are compared with relevant literature findings on renal blood supply of a dog and other sympatric carnivores.
Two morphologically distinct forms of Demodex mites found in dogs with canine demodicosis from Vladivostok, Russia
Authors: Moskvina Tatyana Vladimirovna
Published: March 2017

The aim of this study was to investigate the morphology of Demodex canis and Demodex sp. cornei found in six dogs with canine demodicosis. A deep skin scraping technique was used for Demodex mite detection. Measurement data of 52 adult D. canis mites (26 females, 25 males and one specimen whose sex could not be determined) and 39 adult Demodex sp. cornei mites (22 females, 14 males and three specimens whose sex could not be determined) were reported. The correlation between body size of both Demodex species were estimated by the Student’s t-test. There was a significant correlation between short-tail and long-tail forms and total body length and length of the podosoma and opisthosoma (p<0.05). A significant difference was not found between the length of the gnathosoma and short-tail and long-tail forms (p>0.05). Demodex sp. cornei and D. canis, found in dogs from Vladivostok, were smaller than species from other countries. However, the present data did not significantly differ from other studies with D. canis and Demodex sp. cornei descriptions.
Z-cells and oogonia/oocytes in the advanced process of autophagy are the dominant altered cells in the ovaries of hypothyroid newborn rats
Authors: Danilović Luković Jelena , Korać Aleksandra , Milošević Ivan , Lužajić Tijana , Milanović Zorana , Kovačević Filipović Milica , Radovanović Anita
Published: March 2017

Induced prenatal hypothyroidism in rat pups leads to accelerated primordial follicle assembly and premature follicular atresia with ovary failure. This work investigates the influence of maternal hypothyroidism induced with 6-n-propyl-2-thyouracil (PTU) on the number and morphology of oogonia/oocytes in newborn rat pups with light and transmission electron microscopy. Expression of apoptosis and autophagy markers in oogonia/oocytes were examined using immunohistochemistry. Hypothyroid newborn pups had a decreased number of mitotic and resting oogonia, while the number of altered oogonia/oocytes was increased. Ultrastructural observations revealed the increased presence of degenerated pachytene oocytes (Z-cells) and oogonia/oocytes undergoing autophagy, apoptosis and combined apoptosis and autophagy, in this group. The most abundant altered oogonia/oocytes in the hypothyroid group were those with morphological features of advanced autophagy and Z-cells. The percentage of TUNEL (terminal deoxynucleotidyl transferase dUTP nick end labeling) positive oogonia/oocytes was significantly lower in the hypothyroid group. No significant difference was recorded in the expression of caspase-3, ATG7 and LC3 possibly reflecting that these proteins were not involved in the oogonia/oocyte alteration process during prenatal rat hypothyroidism. The obtained results indicate that developmental hypothyroidism in the offspring enhances the number of Z-cells and oogonia/oocytes altered with the advanced process of autophagy.
D2-40 Immunoreactivity of Lymphatic Vessels Endothelium and Representation of Lymphatic Vessels in the Liver of Human Fetuses of Different Gestational Age
Authors: Jović Marko , Nikolić Ivan , Todorović Vera , Petrović Aleksandar , Petrović Vladimir , Denčić Tijana
Published: March 2017

In the reference literature, there are a few studies on the development of the lymphatic system in the liver, especially human. This study aims to establish the presence, time of appearance, distribution and representation of expression D2-40 molecule – a marker of lymph vessels endothelial cells during the fetal period of the human liver development.

The livers obtained from 20 human fetuses (10 male and 12 female), aged 12-37 gestational weeks, constituted our study material. Paraffin sections, 4 µm thick, were stained with hematoxylin and eosin for histological analysis, and with LSAB2/HRP method for immunohistochemistry using the D2-40 monoclonal antibody to mark lymphatic endothelial cells. The presence of lymphatic vessels was determined by morphometry, calculating their numerical and volume density.

The study showed that expression of D2-40 molecule was absent in the liver lymphatic vessels in the first trimester of development, while in the second trimester intensive D2-40 immunoreactivity was observed in the lymph vessels of the liver capsule, and low D2-40 immunopositivity of the lymph vessels in large portal spaces. In the third trimester, intensive D2-40 immunoreactivity was observed in the lymph vessels of the liver capsule and in the endothelium of numerous lymphatic vessels of various shape and size, located in the smaller and larger portal areas. Volume and numerical density of lymphatic vessels in the portal areas of the liver during fetal development increased from the second to the third trimester of pregnancy, which was proportional to the increase in volume density of the hepatic portal spaces. Based on the obtained results, a conclusion may be drawn that the lymph vessels in the liver can be identified in the first half of the second trimester, and their number was growing proportionally by the end of pregnancy.
Surgical Treatment of an Open Elbow Dislocation with Vascular Injury: A Case Report
Authors: Stojiljković Predrag , Jovanović Milan , Golubović Ivan , Mitković Milan , Mladenović Marko , Tošić Aleksandar
Published: March 2017

Open elbow dislocations with vascular injury are rare injuries and they most commonly occur after a fall from a high or in sports accidents. Close anatomic proximity of the joint to the neurovascular structures put them at risk of concomitant injury. The aim of this paper is to present the method of treatment of this severe injury.

Herein we present a case of a female patient, 43 years old. She had suffered an open elbow dislocation with vascular injury as a result of a fall from the height of 1.5 meters. Seven hours after sustaining the injury and short preoperative preparation, reposition of the elbow, reconstruction of the vascular injury, adequate surgical treatment of the wound and external fixation of the elbow with the Mitković type external fixator were performed under general anesthesia. Four weeks after elbow stabilization with the external fixation, the external fixator was removed. The neurovascular status and final functional result of the treatment after six mounts were good.

Urgent reposition, artery and vein reconstruction, and external fixation are essential in achieving good results in patients with open cubital dislocation accompanied with vascular injury. The Mitković type external fixator provides fast and stable fixation of the elbow after reposition and good conditions for wound care.
Performance Evaluation of Bucket based Excavating, Loading and Transport (BELT) Equipment – An OEE Approach
Authors: Mohammadi Mousa , Rai Piyush , Gupta Suprakash
Published: March 2017

Overall Equipment Effectiveness (OEE) has been used since last over two decades as a measure of performance in manufacturing industries. Unfortunately, enough, application of OEE in mining and excavation industry has not been duly adopted. In this paper an effort has been made to identify the OEE for performance evaluation of Bucket based Excavating, Loading and Transport (BELT) equipment. The conceptual model of OEE, as used in the manufacturing industries, has been revised to adapt to the BELT equipment. The revised and adapted model considered the operational time, speed and bucket capacity utilization losses as the key OEE components for evaluating the performance of BELT equipment. To illustrate the efficacy of the devised model on real-time basis, a case study was undertaken on the biggest single bucket excavating equipment – the dragline, in a large surface coal mine. One-year data was collected in order to evaluate the proposed OEE model.
Feed Material Influence on the Dynamics of the Suspended Screen at Its Steady State Operation and Transient States
Authors: Michalczyk Jerzy , Bednarski Łukasz , Gajowy Marek
Published: March 2017

The influence of the feed material on steady vibrations as well as on the transient resonance during the start-up and coasting of the suspended screen, was analysed in the hereby paper. The influence of the feed material presence on the possibility of performing the first half-turn of the vibrator was also established. The original, feed material simulation model reflecting its layer properties and diversification of feed particles vibrations along the screen riddle – specially developed for this aim – was applied in investigations.
Study of Loading and Running Characteristic of Hydraulic Support in Underhand Mining Face
Authors: Cheng Jing-Yi , Zhang Yi-Dong , Cheng Liang , Ji Ming , Gu Wei , Gao Lin-Sheng
Published: March 2017

According to complex geological conditions of working face E1108 in Xin-ji mine #2, loading and running characteristic of hydraulic support, influence of depression angle on mining pressure behaviors, as well as relation between advancing speed and the support loading were measured and analyzed. The results indicate that depression angle is inversely proportional to support resistance, in other words, larger depression angle area coincides with lower support resistance area. Moreover, support resistance is generally high when working face advancing speed is slow. Technologies for controlling hydraulic support stability such as improving advancing speed properly, controlling mining height and increasing support resistance are put forward based on research.
Compressive Lumbar Disc Hernia Spontaneously Disapeared in a Few Years - Case Report
Authors: Balasa D. , Ciufu Carmen , Baz R. , Hancu Anca
Published: March 2017

We present a patient with left compressive L5-S1 lumbar disc hernia in lateral reces and foramina revealed by high intensity pain (Visual Autologus Scale 7/10) and paresthesias on the left S1 dermatoma for 5 months. He refused surgery and followed conservative treatment with very good results after 6 months. The radicular S1 pain became of a small intensity (Visual Autologus Scale 2-3/10) and intermitent and after one year it completely disapeared. After 4 years he repeated the lumbar magnetic resonance imaging which proved the disapearance of the L5-S1 lumbar disc hernia.
Myocardial Contrast Agents – Safety Considerations and Clinical Efficacy in Stress Echocardiography
Authors: Maier Anca , Opris Maria Mihaela , Sirbu Voichita , Brinzaniuc Klara
Published: March 2017

Transthoracic echocardiographic examination is known to be a safe, non-invasive and reproducible method, used in every day clinical practice to obtain important information about cardiac structure and function. Unfortunately, a significant proportion of studies have highlighted the considerable technically difficultly in producing diagnostic images due to a poor acoustic window and more than 33% of patients undergoing stress echocardiography have suboptimal echocardiographic images. All these limitations have led to the use of contrast agents to improve the quality of standard ultrasound examination to provide a better delineation of left ventricle endocardial borders or to obtain information that cannot be achieved by using standard echocardiography, such as assessing myocardial microcirculation and therefore perfusion. This paper sought to review the clinical efficacy and safety of ultrasound contrast agents focusing on stress echocardiography.
A candidate reference method for serum potassium measurement by inductively coupled plasma mass spectrometry
Authors: Yan Ying , Han Bingqing , Zeng Jie , Zhou Weiyan , Zhang Tianjiao , Zhang Jiangtao , Chen Wenxiang , Zhang Chuanbao
Published: March 2017

Background:

Potassium is an important serum ion that is frequently assayed in clinical laboratories. Quality assurance requires reference methods; thus, the establishment of a candidate reference method for serum potassium measurements is important.

Methods:

An inductively coupled plasma mass spectrometry (ICP-MS) method was developed. Serum samples were gravimetrically spiked with an aluminum internal standard, digested with 69% ultrapure nitric acid, and diluted to the required concentration. The

Results:

The correlation coefficients between the measured

Conclusions:

The new ICP-MS method is specific, precise, simple, and low-cost, and it may be used as a candidate reference method for standardizing serum potassium measurements.
Serum complexed and free prostate-specific antigen (PSA) for the diagnosis of the polycystic ovarian syndrome (PCOS)
Authors: Diamandis Eleftherios P. , Stanczyk Frank Z. , Wheeler Sarah , Mathew Anu , Stengelin Martin , Nikolenko Galina , Glezer Eli N. , Brown Marshall D. , Zheng Yingye , Chen Yen-Hao , Wu Hsiao-Li , Azziz Ricardo
Published: March 2017

Background:

Polycystic ovarian syndrome (PCOS) is a common cause of reproductive and metabolic dysfunction. We hypothesized that serum prostate-specific antigen (PSA) may constitute a new biomarker for hyperandrogenism in PCOS.

Methods:

We conducted a cross-sectional study of 45 women with PCOS and 40 controls. Serum from these women was analyzed for androgenic steroids and for complexed PSA (cPSA) and free PSA (fPSA) with a novel fifth- generation assay with a sensitivity of ~10 fg/mL for cPSA and 140 fg/mL for fPSA.

Results:

cPSA and fPSA levels were about three times higher in PCOS compared to controls. However, in PCOS, cPSA and fPSA did not differ according to waist-to-hip ratio, Ferriman-Gallwey score, or degree of hyperandrogenemia or oligo-ovulation. In PCOS and control women, serum cPSA and fPSA levels were highly correlated with each other, and with free and total testosterone levels, but not with other hormones. Adjusting for age, body mass index (BMI) and race, cPSA was significantly associated with PCOS, with an odds ratio (OR) of 5.67 (95% confidence interval [CI]: 1.86, 22.0). The OR of PCOS for fPSA was 7.04 (95% CI: 1.65, 40.4). A multivariate model that included age, BMI, race and cPSA yielded an area-under-the-receiver-operating-characteristic curve of 0.89.

Conclusions:

Serum cPSA and fPSA are novel biomarkers for hyperandrogenism in PCOS and may have value for disease diagnosis.