bluuebunny/crossref_metadata_2025 huggingface dataset:
Dos zebus e seus clones: valor e pedigree em um mercado de elite
Authors: Leal Natacha Simei
Published: December 2016

O Brasil comercializa os bovinos de “elite” de origem zebu (da subespécie Bos taurus indicus) – modelos raciais, estéticos e reprodutivos, com pedigree – mais caros do planeta, além disso, através de “parcerias” entre Estado, fazendeiros e laboratórios privados, está à frente no uso e pesquisa de biotecnologias (inseminação artificial, fertilizações in vitro, clonagens) para produzir esses animais. No ano de 2002, a Embrapa realizou um procedimento bem-sucedido de transferência nuclear. Desde então, fazendeiros que investiram em pesquisas experimentais na técnica, passaram a produzir e comercializar clones de importantes reprodutores. Em 2007, um clone da “doadora” Bilara vii, a vaca Ópera, da raça Nelore, foi comercializado por um milhão de reais em um leilão. Apesar das altas cifras pagas pelo animal, ele não pode receber pedigree; na época, nem a Associação Brasileira dos Criadores de Zebu (instituição que controla os padrões raciais e o fornecimento de registros genealógicos de espécimes zebuínos no Brasil), tampouco o Ministério da Agricultura, conseguiram lidar com as controvérsias que Ópera mobilizava: indubitavelmente, ela era “de elite”, mas quem eram, de fato, seus progenitores? Este artigo, através da descrição das controvérsias envolvendo os primeiros procedimentos de transferência nuclear e comércio de bovinos clonados país – pelos laboratórios e em leilões – pretende iluminar a produção e realização do mercado de gado de “elite” brasileiro. Anseia discutir sobre a centralidade da ideia de pedigree na pecuária zebuína, os efeitos do uso de tecnologias reprodutivas, a coalizão de interesses entre empresariado rural e Estado no Brasil, além de refletir sobre o estatuto e valor de bovinos e criadores de “elite”.
INNOVATION Study (Impact of Immediate Stent Implantation Versus Deferred Stent Implantation on Infarct Size and Microvascular Perfusion in Patients With ST-Segment–Elevation Myocardial Infarction)
Authors: Kim Je Sang , Lee Hyun Jong , Woong Yu Cheol , Kim Yang Min , Hong Soon Jun , Park Jae Hyung , Choi Rak Kyeong , Choi Young Jin , Park Jin Sik , Kim Tae Hoon , Jang Ho-Jun , Joo Hyung Joon , Cho Sang-A , Ro Young Moo , Lim Do-Sun
Published: December 2016

Background—

The aim of this study was to assess whether deferred stenting (DS) reduces infarct size and microvascular obstruction (MVO) compared with immediate stenting (IS) in primary percutaneous coronary intervention for ST-segment–elevation myocardial infarction.

Methods and Results—

From February 2013 to August 2015, 114 patients (mean age: 69 years) were randomized into the following 2 groups: DS with an intention to stent 3 to 7 days later or IS after primary reperfusion in 2 centers. The primary and secondary end points were infarct size and the incidence of MVO, respectively, assessed by cardiac magnetic resonance imaging at 30 days after primary reperfusion. The median time to the second procedure in the DS was 72.8 hours. Six patients in the DS group were crossed over to the IS group because of progression of dissection or safety concerns after randomization. In the intention-to-treat analysis, DS did not significantly reduce infarct size (15.0% versus 19.4%;
P
=0.112) and the incidence of MVO (42.6% versus 57.4%;
P
=0.196), compared with IS. However, in anterior wall myocardial infarction, infarct size (16.1% versus 22.7%;
P
=0.017) and the incidence of MVO (43.8% versus 70.3%;
P
=0.047) were significantly reduced in the DS group. There was no urgent revascularization event during deferral period.

Conclusions—

A routine DS did not significantly reduce infarct size and MVO compared with IS, although it was safe. The beneficial effect of DS in patients with anterior myocardial infarction should be confirmed by larger randomized studies.

Clinical Trial Registration—

URL:
http://www.clinicaltrials.gov
. Unique identifier: NCT02324348.
Discharge Disposition After Stroke in Patients With Liver Disease
Authors: Parikh Neal S. , Merkler Alexander E. , Schneider Yecheskel , Navi Babak B. , Kamel Hooman
Published: December 2016

Background and Purpose—

Liver disease is associated with both hemorrhagic and thrombotic processes, including an elevated risk of intracranial hemorrhage. We sought to assess the relationship between liver disease and outcomes after stroke, as measured by discharge disposition.

Methods—

Using administrative claims data, we identified a cohort of patients hospitalized with stroke in California, Florida, and New York from 2005 to 2013. The predictor variable was liver disease. All diagnoses were defined using validated diagnosis codes. Ordinal logistic regression was used to analyze the association between liver disease and worsening discharge disposition: home, nursing/rehabilitation facility, or death. Secondarily, multiple logistic regression was used to analyze the association between liver disease and in-hospital mortality. Models were adjusted for demographics, vascular risk factors, and comorbidities.

Results—

We identified 121 428 patients with intracerebral hemorrhage and 703 918 with ischemic stroke. Liver disease was documented in 13 584 patients (1.7%). Liver disease was associated with worse discharge disposition after both intracerebral hemorrhage (global odds ratio, 1.28; 95% confidence interval, 1.19–1.38) and ischemic stroke (odds ratio, 1.23; 95% confidence interval, 1.17–1.29). Similarly, liver disease was associated with in-hospital death after both intracerebral hemorrhage (odds ratio, 1.33; 95% confidence interval, 1.23–1.44) and ischemic stroke (odds ratio, 1.60; 95% confidence interval, 1.51–1.71).

Conclusions—

Liver disease was associated with worse hospital discharge disposition and in-hospital mortality after stroke, suggesting worse functional outcomes.
Hashtag Sense Clustering Based on Temporal Similarity
Authors: Stilo Giovanni , Velardi Paola
Published: December 2016

Hashtags are creative labels used in micro-blogs to characterize the topic of a message/discussion. Regardless of the use for which they were originally intended, hashtags cannot be used as a means to cluster messages with similar content. First, because hashtags are created in a spontaneous and highly dynamic way by users in multiple languages, the same topic can be associated with different hashtags, and conversely, the same hashtag may refer to different topics in different time periods. Second, contrary to common words, hashtag disambiguation is complicated by the fact that no sense catalogs (e.g., Wikipedia or WordNet) are available; and, furthermore, hashtag labels are difficult to analyze, as they often consist of acronyms, concatenated words, and so forth. A common way to determine the meaning of hashtags has been to analyze their context, but, as we have just pointed out, hashtags can have multiple and variable meanings. In this article, we propose a temporal sense clustering algorithm based on the idea that semantically related hashtags have similar and synchronous usage patterns.
A new biogeographically disjunct giant gecko (Gehyra: Gekkonidae: Reptilia) from the East Melanesian Islands
Authors: OLIVER PAUL M. , CLEGG JONATHAN R. , FISHER ROBERT N. , RICHARDS STEPHEN J. , TAYLOR PETER N. , JOCQUE MERLIJN M. T.
Published: December 2016

The East Melanesian Islands have been a focal area for research into island biogeography and community ecology. However, previously undescribed and biogeographically significant new species endemic to this region continue to be discovered. Here we describe a phylogenetically distinct (~20% divergence at the mitochondrial ND2 gene) and biogeographically disjunct new species of gecko in the genus Gehyra, from the Admiralty and St Matthias Islands. Gehyra rohan sp. nov. can be distinguished from all congeners by the combination of its very large size, ring of bright orange scales around the eye, moderate degree of lateral folding on the limbs and body, and aspects of head, body and tail scalation. Molecular data indicate mid to late Miocene divergence of the new species from nearest relatives occurring nearly 2000 kilometres away in Vanuatu and Fiji. Large Gehyra have not been recorded on the intervening large islands of the Bismark Archipelago (New Britain and New Ireland) and the Solomon Islands, suggesting this dispersal pre-dated the current configuration of these islands, extinction in intervening regions, or potentially elements of both. Conversely, low genetic divergence between disjunct samples on Manus and Mussau implies recent overseas dispersal via either natural or anthropogenic means.
Two new species of the genus Phaea Newman, 1840 (Coleoptera: Cerambycidae) from Mexico
Authors: TOLEDO-HERNÁNDEZ VÍCTOR HUGO , MARTÍNEZ-HERNÁNDEZ JOSÉ G. , BEZARK LARRY
Published: December 2016

Two new species of the genus Phaea Newman are described from Mexico. Phaea chemsaki sp. nov. from Chiapas, and P. parallela sp. nov. from Morelos. The descriptions are supplemented with photographs.
Emotion Correlates of Bullies, Victims, and Bully-Victims in African American Children
Authors: Kelsey Caroline , Zeman Janice , Dallaire Danielle
Published: December 2016

Bullying is a pervasive and widely studied problem. Less is known about the emotion correlates that accompany being a bully, being a victim of bullying, and experiencing both bullying and victimization for African American elementary-school-age students. The current study examined differences in emotion dysregulation and internalizing symptoms (depression, anxiety) across levels of bullying and victimization. Children ( N = 336, Mage = 9.58 years, 42.3% boys, 100% African American) were recruited from two inner-city elementary schools and completed self- and peer-reports of bullying and self-reports of victimization, emotion dysregulation, and internalizing symptoms. Results indicated that emotion dysregulation and anxiety symptoms were predicted by an interaction between self-reported bullying and victimization. For children low in victimization, higher levels of self-reported bullying predicted an increase in emotion dysregulation and anxiety symptoms. However, for children high in victimization, bullying was not predictive of these outcomes. Depressive symptoms were predicted by self- and peer-reported bullying and self-reported victimization. Understanding underlying emotional correlates of bullying and victimization within this context have important implications for prevention programs.
The link between tourism activities and economic growth: Evidence from China’s provinces
Authors: Wu Tsung-Pao , Wu Hung-Che
Published: December 2016

This study explores the causal relationship between international tourism receipts and economic growth in China’s eight central provinces (Shanxi, Jilin, Heilongjiang, Anhui, Jiangxi, Henan, Hubei and Hunan) by analyzing these provinces for the period from 1995 to 2014, accounting for both dependency and heterogeneity across provinces. The empirical results of this study support evidence for the growth hypothesis in Hunan Province. A reverse relationship supports evidence on the conservation hypothesis for the provinces, such as Shanxi, Jiangxi, and Henan. A reciprocal causal relationship was found for Jilin, Anhui, and Hubei, while the result of a neutrality hypothesis supported only one of the provinces in Heilongjiang. The empirical findings of this study provide important policy implications for China’s eight central provinces.
Reforms in the policy of English language teaching in Malaysia
Authors: Rashid Radzuwan AB , Abdul Rahman Shireena Basree , Yunus Kamariah
Published: December 2016

This paper reviews reforms related to English language teaching in the Malaysian education system. It begins by tracing the history of Malaysia as a former British colony which has had significant influences on the status of English in the country. Then, it reviews the key educational reforms which have mainly centred on language policy, thus putting pressure on teachers who are at the front-line for the implementation of the new reforms. This is followed by the discussion on the changing approaches in the curriculum and methodology of English language teaching. This paper also reviews the formal professional development programmes which reveal that Malaysian teachers are not always given adequate and continuous support to cope with the ongoing reforms. The paper concludes that even though the changes in policies aimed to improve the quality of education, implementation was often made in haste, causing a loud public outcry from teachers.
Local availability of green and blue space and prevalence of common mental disorders in the Netherlands
Authors: de Vries Sjerp , ten Have Margreet , van Dorsselaer Saskia , van Wezep Manja , Hermans Tia , de Graaf Ron
Published: December 2016

Background

Previous studies revealed a relationship between residential green space availability and health, especially mental health. Studies on blue space are scarcer and results less conclusive.

Aims

To investigate the hypotheses that green and blue space availability are negatively associated with anxiety and mood disorders, and positively associated with self-reported mental and general health.

Method

Health data were derived from a nationally representative survey (NEMESIS-2,n=6621), using a diagnostic interview to assess disorders. Green and blue space availability were expressed as percentages of the area within 1 km from one's home.

Results

The hypotheses were confirmed, except for green space and mood disorders. Associations were generally stronger for blue space than for green space, with ORs up to 0.74 for a 10%-point increase.

Conclusions

Despite the different survey design and health measures, the results largely replicate those of previous studies on green space. Blue space availability deserves more systematic attention.
Missed opportunity to screen and diagnose PTSD and depression among deploying shipboard US military personnel
Authors: Harbertson Judith , Hale Braden R. , Michael Nelson L. , Scott Paul T.
Published: December 2016

Background

Depression and post-traumatic stress disorder (PTSD) are significant risks for suicide and other adverse events among US military personnel, but prevalence data among ship-assigned personnel at the onset of deployment are unknown.

Aims

To determine the prevalence of shipboard personnel who screen positive for PTSD and/or major depressive disorder (MDD) at the onset of deployment, and also those who reported these diagnoses made by a physician or healthcare professional in the year prior to deployment.

Method

Active-duty ship-assigned personnel (N = 2078) completed anonymous assessments at the beginning of deployment. Depression was measured using the Center for Epidemiologic Studies Depression Scale (CES-D; score of ≥22), and PTSD was assessed using the PTSD Checklist–Civilian Version (PCL-C; both score and symptom criteria were used).

Results

In total, 7.3% (n = 151 of 2076) screened positive for PTSD and 22% (n = 461 of 2078) for MDD at deployment onset. Only 6% and 15% of those who screened positive for PTSD or MDD, respectively, had been diagnosed by a healthcare professional in the past year.

Conclusions

Missed opportunities for mental healthcare among screen-positive shipboard personnel reduce the benefits associated with early identification and linkage to care. Improved methods of mental health screening that promote early recognition and referral to care may mitigate psychiatric events in theatre.
Disturbed EEG sleep, paranoid cognition and somatic symptoms identify veterans with post-traumatic stress disorder
Authors: Moldofsky Harvey , Rothman Lorne , Kleinman Robert , Rhind Shawn G. , Richardson J. Donald
Published: December 2016

Background

Chronic post-traumatic stress disorder (PTSD) behavioural symptoms and medically unexplainable somatic symptoms are reported to occur following the stressful experience of military combatants in war zones.

Aims

To determine the contribution of disordered EEG sleep physiology in those military combatants who have unexplainable physical symptoms and PTSD behavioural difficulties following war-zone exposure.

Method

This case-controlled study compared 59 veterans with chronic sleep disturbance with 39 veterans with DSM-IV and clinician-administered PTSD Scale diagnosed PTSD who were unresponsive to pharmacological and psychological treatments. All had standardised EEG polysomnography, computerised sleep EEG cyclical alternating pattern (CAP) as a measure of sleep stability, self-ratings of combat exposure, paranoid cognition and hostility subscales of Symptom Checklist-90, Beck Depression Inventory and the Wahler Physical Symptom Inventory. Statistical group comparisons employed linear models, logistic regression and chi-square automatic interaction detection (CHAID)-like decision trees.

Results

Veterans with PTSD were more likely than those without PTSD to show disturbances in non-rapid eye movement (REM) and REM sleep including delayed sleep onset, less efficient EEG sleep, less stage 4 (deep) non-REM sleep, reduced REM and delayed onset to REM. There were no group differences in the prevalence of obstructive sleep apnoeas/hypopnoeas and periodic leg movements, but sleep-disturbed, non-PTSD military had more EEG CAP sleep instability. Rank order determinants for the diagnosis of PTSD comprise paranoid thinking, onset to REM sleep, combat history and somatic symptoms. Decision-tree analysis showed that a specific military event (combat), delayed onset to REM sleep, paranoid thinking and medically unexplainable somatic pain and fatigue characterise chronic PTSD. More PTSD veterans reported domestic and social misbehaviour.

Conclusions

Military combat, disturbed REM/non-REM EEG sleep, paranoid ideation and medically unexplained chronic musculoskeletal pain and fatigue are key factors in determining PTSD disability following war-zone exposure.
Using daily monitoring of psychiatric symptoms to evaluate hospital length of stay
Authors: Page Andrew C. , Cunningham Nadia K. , Hooke Geoffrey R.
Published: December 2016

Background

Routine symptom monitoring and feedback improves out-patient outcomes, but the feasibility of its use to inform decisions about discharge from in-patient care has not been explored.

Aims

To examine the potential value to clinical decision-making of monitoring symptoms during psychiatric in-patient hospitalisation.

Method

A total of 1102 in-patients in a private psychiatric hospital, primarily with affective and neurotic disorders, rated daily distress levels throughout their hospital stay. The trajectories of patients who had, and had not, met a criterion of clinically significant improvement were examined.

Results

Two-thirds of patients (n=604) met the clinically significant improvement criterion at discharge, and three-quarters (n=867) met the criterion earlier during their hospital stay. After meeting the criterion, the majority (73.2%) showed stable symptoms across the remainder of their hospital stay, and both classes showed substantially lower symptoms than at admission.

Conclusions

Monitoring of progress towards this criterion provides additional information regarding significant treatment response that could inform clinical decisions around discharge readiness.
Different views on hepatic encephalopathy: patients, relatives and nurses
Authors: Grønkjær Lea Ladegaard , Andersen Nanna Gasberg , Hansen Lene Bolvig , Sehstedt Thomas Hoppe , Svensson Nanna Tholstrup , Sømod Ida Elbek , Norlyk Annelise , Bager Palle
Published: December 2016

This study aimed to explore how patients with liver cirrhosis experienced overt hepatic encephalopathy (HE), how patients' close relatives perceived having a relative with HE and how nurses described the challenges related to caring for patients with HE. The study was based on semi-structured interviews with eight patients, eight relatives and six nurses. The collected data were analysed according to Malterud's systematic text condensation. The analysis process identified four themes (loss, anxiety, dependence and isolation) for patients, five themes (powerlessness, taking control, support, on guard and information) for relatives and four themes (unpredictable nature, becoming familiar with patients, protecting oneself and doing right) for nurses. The findings reveal new perspectives on HE and can be said to provide an important contribution to gaining a deeper understanding of the experience and impact of HE.
Todos somos artistas; todos somos maniquíes. O sobre el narcisismo en el mundo contemporáneo
Authors: Rivero Moreno Luis David
Published: December 2016

Gran parte de la necesidad humana de representación de su propia figura se ha vertido en la construcción de dobles en tres dimensiones. El maniquí será uno de los más utilizados en el ámbito artístico ya desde las primeras vanguardias. Planteado no solo como sustituto sino competidor, adquirirá una autonomía que hace al hombre caer en la duda sobre la vitalidad de semejantes figuras. Tras todo quizás no esté más que el deseo de proyección de vida en un “otro” sobre el que autorretratarse. La personalidad artística de Narcissister pone al descubierto esa necesidad onanista de vernos reflejados en toda superficie.
La caja del órgano barroco de la iglesia de san Miguel de Larraga, obra de Miguel de Zufía (1775-1776)
Authors: Tarifa Castilla María Josefa
Published: December 2016

El presente artículo aborda el estudio histórico-artístico de la caja del órgano barroco de la iglesia parroquial de San Miguel de Larraga (Navarra). Estructura de madera que ejecutó Miguel Zufía entre 1775 y 1776 y policromó en 1803 Juan José del Rey, para albergar el instrumento musical realizado por el organero Diego Gómez, resultando uno de los ejemplos más sobresalientes de la organería navarra. La consulta de diferentes archivos ha permitido localizar la documentación inédita de la contratación de la caja y el órgano dieciochesco, así como de las reformas del instrumento en 1878 por Saturnino Inchaurbe y José Puyó.
Centinelas de la Patria. Regionalismo vasco y nacionalización española en el siglo XIX
Authors: Rubio Pobes Coro
Published: December 2016

Este artículo estudia las expresiones de patriotismo español y la idea de nación española presentes en el discurso del fuerismo vasco, hegemónico en las Provincias Vascongadas durante el siglo xix. Su objetivo es analizar su significado y reflexionar sobre el papel que este discurso, expresión de un temprano regionalismo político, el primero en madurar en España, pudo desempeñar como mecanismo informal de nacionalización española, y a la vez constituir un sustrato cultural del que se nutriría el nacionalismo vasco finisecular.
Bajo la sombra de la Comuna: sindicalismo y republicanismo en la Barcelona de 1871
Authors: Garcia-Balañà Albert
Published: December 2016

El artículo pretende reabrir el debate historiográfico sobre el impacto de la Comuna de París en la España de 1871. Tras valiosas contribuciones que han subrayado la llegada de relatos y refugiados de la Comuna a la España en revolución, o las presiones de Thiers sobre el gabinete Serrano-Sagasta para la persecución de estos últimos, este artículo sostiene que fueron las concretas experiencias autóctonas de conflicto social y político las que resultaron fundamentales en la recepción española de la revolución parisina. Los debates parlamentarios de mayo de 1871 sobre la Comuna y la AIT nacieron de un específico episodio local de protesta obrera y movilización política plebeya. Un episodio que tuvo lugar en Barcelona durante los casi tres meses de vida de la Comuna. Y un episodio que, como tal, apenas ha recibido atención historiográfica. La paralización sindical de la mayor fábrica textil de España, la Fábrica Batlló, y la mayor victoria electoral del Partido Republicano Democrático Federal (PRDF) tras la caída de Isabel II, confluyeron en la Barcelona de aquella primavera. La Comuna contribuyó a fundir ambos acontecimientos; a ella recurrió el patriciado barcelonés para desacreditarlos y hostigarlos, urgiendo la intervención de Sagasta. La ofensiva gubernamental contra sindicalistas y republicanos locales se cobijó bajo el manto del ataque de Versalles sobre París, exactamente durante los mismos días de mayo de 1871.
El registro material del colmenar ibérico de la Fonteta Ràquia (Riba-Roja, València)
Authors: Quixal Santos David , Jardón Giner Paula
Published: December 2016

La excavación arqueológica en 2008 del yacimiento de la Fonteta Ràquia (Riba-Roja del Túria, València) permitió documentar un pequeño asentamiento rural de la Edetania, territorio de la antigua ciudad ibérica de Edeta / Tossal de Sant Miquel (Llíria, València). El núcleo estuvo ocupado entre finales del s. V a.C. y finales del III / comienzos del II a.C. Destaca, por encima de todo, por una gran especialización en apicultura, tal y como demuestra el hallazgo de miles de fragmentos de aproximadamente 200 colmenas cerámicas, superando con creces los registros precedentes de este tipo de actividad en Iberia y el Mediterráneo en general.
Los objetos de hueso de la tumba 150 de la necrópolis ibérica de Tútugi (Galera, Granada): ¿instrumentos de escritura?
Authors: Simón Cornago Ignacio
Published: December 2016

Se propone la posibilidad de que dos piezas de hueso de la tumba 150 de la necrópolis de Tútugi sean instrumentos de escritura, concretamente un estilo y una regla.
Las lucernas republicanas de Lucentum (Tossal de Manises, Alacant)
Authors: Garcia Barrachina Anna
Published: December 2016

Presentamos en este artículo las lucernas de tipología republicana procedentes de la ciudad romana de Lucentum. Las lucernas se presentan enmarcadas tipológicamente y se proporciona su datación según su contexto estratigráfico, se recopilan además las marcas existentes sobre ellas y los motivos decorativos que presentan.
Los morteros centroitálicos procedentes de los rellenos constructivos del anfiteatro de Segobriga. Revisión cronológica
Authors: Cebrián Fernández Rosario , Hortelano Uceda Ignacio
Published: December 2016

La excavación arqueológica realizada en el período 2011-2013 en el anfiteatro de Segobriga ha documentado treinta y seis ejemplares de morteros de procedencia centroitálica. Su hallazgo en vertidos de nivelación y rellenos constructivos de cronología vespasianea aporta una fecha ante quem para la comercialización en la ciudad de la forma Dramont D 2, fase 3. Los sellos conservados en algunos morteros mencionan a varios alfareros y propietarios de los talleres en los que se fabricaron, entre ellos, Statius Marcius Suavillus, un officinator sólo documentado hasta la fecha en una estampilla sobre dolium hallada en Roma (CIL XV 1291).
Fragmento inédito del sarcófago de la Colección Alessadri (Verona). Aspectos iconográficos, cronológicos y productivos
Authors: Quattrocchi Luigi
Published: December 2016

El objetivo de este artículo es publicar un fragmento de mármol correspondiente a un sarcófago de una colección privada. Intentamos proporcionar comparaciones de estilo con tal de datar el fragment. Asimismo, proponemos una hipótesis sobre la identidad del personaje i sobre el lugar de producción del sarcófago.
Un tresoret tardoromà al Tossal de les Basses (Alacant)
Authors: Garrigós i Albert Immaculada
Published: December 2016

L’estudi següent presenta la troballa monetària esdevinguda durant les excavacions arqueològiques a l’enclavament del Tossal de les Basses (Alacant), a una vil·la romana de cronologia molt ampla. Es realitza una catalogació del tresoret, amb un període que compren els segles IV-V dC, com també consideracions sobre circulació monetària a l’assentament així com a les comarques meridionals del País Valencià.
La presa de la Garganta del Ciervo, s. XII (Segura de la Sierra, Jaén, España): aportaciones a la ingeniería hidráulica andalusí
Authors: Salvatierra Cuenca Vicente , Gómez Cabezas Francisco
Published: December 2016

En este texto analizamos una notable presa islámica localizada en la Sierra de Segura, fechada en el siglo XII. Su envergadura, 11 m de altura y 9 m de grosor, su situación en una zona sustancialmente llana, su técnica de fabricación, el pantano que generaba, etc. la convierten en principio en un elemento muy atípico dentro de la arquitectura de regadío andalusí. Además de realizar su descripción, nos proponemos discutir hasta qué punto la finalidad de esta estructura era realmente diferente a lo que se hacía en la época, y si supone por tanto un cambio tecnológico y social. O si su configuración escondía otros objetivos.
Accelerometer vs. Electromyogram in Activity Recognition
Authors: Koskimaki Heli , Siirtola Pekka
Published: December 2016

In this study, information from wearable sensors is used to recognize human activities. Commonly the approaches are based on accelerometer data while in this study the potential of electromyogram (EMG) signals in activity recognition is studied. The electromyogram data is used in two different scenarios: 1) recognition of completely new activities in real life and 2) to recognize the individual activities. In this study, it was shown that in gym settings electromyogram signals clearly outperforms the accelerometer data in recognition of completely new sets of gym movements from streaming data even though the sensors would not be positioned directly to the muscles trained. Nevertheless, in recognition of individual activities the EMG itself does not provide enough information to recognize activities accurately.
Review of the Main Security Problems with Multi-Agent Systems used in E-commerce Applications
Authors: González Briones Alfonso , Chamoso Pablo , Barriuso Alberto
Published: December 2016

The ability to connect to the Internet from a wide variety of devices such as smart phones, IoT devices and desktops at anytime and anywhere, produces a large number of e-commerce transactions, such as purchases of clothes, ticket entrances for performances, or banking operations. The increasing number of these transactions has also created an increase in the number of threats and attacks by third parties to access user data banks. It is important to control the access procedure to user data so that the number of threats does not continue to grow. To do so, it is necessary to prevent unauthorized access, theft and fraud in electronic commerce, which is required to ensure the safety of these transactions. Many e-commerce platforms are developed through multi-agent-systems because they include certain advantages to control the product, resource management, task distribution, etc. However, there are a number of threats that can jeopardize the safety of the agents that make up the system. These issues must be taken into account in the development of these multi-agent systems. However, existing methods of development do not cover in depth the issue of security. It is necessary to present and classify the potential security flaws of multi-agent systems. Therefore, the present research presents a review of the main vulnerabilities that occur in multi-agent systems responsible for managing e-commerce applications, as well as the proposed solutions to the major security problems on these platform systems. The main conclusions provided by this research is the need to optimize security measures and enhance the different security solutions applied in e-commerce applications in order to prevent identity theft, access to private data, access control, etc. It is therefore essential to continue to develop the security methods employed in applications such as e-commerce as different types of attacks and threats continue to evolve.
The Algorithm of the Snail: An Example to Grasp the Window of Opportunity to Boost Big Data
Authors: Monino Jean Louis , Sedkaoui Soraya
Published: December 2016

This work explores a new application which can effectively meet different localization accuracy requirements of most data location services studying the interactions between customers and suppliers. It helps to have the status or position of what is sought with respect to an address that summarizes thus a reference point which is the point of research. This proposal explains what snail algorithm is and how we can benefit from using it for the localization of information for business applications especially in the field of analytics. A business application using our algorithm has been developed by the Autour.com company (located in the department of Herault, Montpellier city) to illustrate its feasibility and availability. The results show that our algorithm can improve the localization accuracy.
Time, Temporality, and Internationalization: The Relationship among Point in Time of, Time to, and Speed of International Expansion
Authors: Hilmersson Mikael , Johanson Martin , Lundberg Heléne , Papaioannou Stylianos
Published: December 2016

Speed of internationalization is a multidimensional concept with performance consequences, but little is known about the interrelatedness between different time-related concepts. The authors address this deficiency by developing three hypotheses, which are confronted with a data set collected on site at 203 small and medium-sized enterprises. The analysis reveals that (1) the longer the time to internationalization, the lower the speed of international expansion; (2) the earlier the point in time when internationalization starts, the lower the speed of international expansion; and (3) there is an antagonistic interaction effect revealing that the negative effect on the speed of international expansion caused by a longer time to internationalization is moderated by the point in time when internationalization starts. The study contributes to theory by examining the interrelatedness between temporal concepts in the internationalization literature and by showing how the underlying mechanisms influencing internationalization speed change over time. For managers, insights into the importance of time and temporality for successful international expansion are provided.
The peiminine stimulating autophagy in human colorectal carcinoma cells via AMPK pathway by SQSTM1
Authors: Zheng Zhi , He Qinsi , Xu Liting , Cui Wenhao , Bai Hua , Zhang Zhe , Rao Jun , Dou Fangfang
Published: December 2016

Autophagy is a conserved catabolic process, which functions in maintenance of cellular homeostasis in eukaryotic cells. The self-eating process engulfs cellular long-lived proteins and organelles with double-membrane vesicles, and forms a so-called autophagosome. Degradation of contents via fusion with lysosome provides recycled building blocks for synthesis of new molecules during stress, e.g. starvation. Peiminine is a steroidal alkaloid extracted from Fritillaria thunbergii which is widely used in Traditional Chinese Medicine. Previously, peiminine has been identified to induce autophagy in human colorectal carcinoma cells. In this study, we further investigated whether peiminine could induce autophagic cell death via activating autophagy-related signaling pathway AMPK-mTOR-ULK by promoting SQSTM1(P62). Xenograft tumor growth in vivo suggested that both peiminine and starvation inhibit the growth of tumor size and weight, which was prominently enhanced when peiminine and starvation combined. The therapeutical effect of peiminine in cancer treatment is to be expected.
The solvable length of groups of local diffeomorphisms
Authors: Ribón Javier
Published: December 2016

We are interested in the algebraic properties of groups of local biholomorphisms and their
consequences. A natural question is whether the complexity of solvable groups is bounded
by the dimension of the ambient space. In this spirit we
show that

2
⁢
n

+
1

{2n+1}

is the sharpest upper bound for the derived length of solvable subgroups
of the group

Diff
⁢

(

ℂ
n

,
0
)

{\mathrm{Diff}({\mathbb{C}}^{n},0)}

of local complex analytic diffeomorphisms
for

n
=

2
,
3
,
4
,
5

{n=2,3,4,5}

.
An empirical comparison of some
experimental designs for the valuation of
large variable annuity portfolios
Authors: Gan Guojun , Valdez Emiliano A.
Published: December 2016

Variable annuities contain complex guarantees, whose fair market value cannot be calculated in
closed form. To value the guarantees, insurance companies rely heavily on Monte Carlo simulation, which
is extremely computationally demanding for large portfolios of variable annuity policies. Metamodeling approaches
have been proposed to address these computational issues. An important step of metamodeling
approaches is the experimental design that selects a small number of representative variable annuity policies
for building metamodels. In this paper, we compare empirically several multivariate experimental design
methods for the GB2 regression model, which has been recently discovered to be an attractive model
to estimate the fair market value of variable annuity guarantees. Among the experimental design methods
examined, we found that the data clustering method and the conditional Latin hypercube sampling method
produce the most accurate results.
Refinements of the weighted generalized trapezoid inequality in terms of cumulative variation and applications
Authors: Liu Wenjun , Zhang Heng
Published: December 2016

In this paper, we first establish some refinements of the weighted generalized trapezoid inequality for functions of bounded variation in terms of a cumulative variation function, and then obtain some perturbed versions of the weighted generalized trapezoid inequality. Several applications for selfadjoint operators on complex Hilbert spaces are also given.
Information Needs in Prisons and Jails: A Discourse Analytic Approach
Authors: Rabina Debbie , Drabinski Emily , Paradise Laurin
Published: December 2016

According to the most recent statistics by the US Department of Justice (“Correctional Populations in the United States, 2014,” accessed September 25, 2016 at
Comparison of foliar fertilizers and growth
regulators on pre-harvest drop and fruit quality of ‘Thompson Navel’ orange
Authors: Mollapur Yaser , Miri Seied Mehdi , Hadavi Ebrahim
Published: December 2016

An investigation was carried out to determine
the ability of foliar fertilizers and growth regulators to
prevent pre-harvest drop and enhance navel orange fruit
quality. Fifteen year old trees of the Thompson Navel
orange variety were sprayed with aqueous solutions of
one of the following: methanol (0.13%), calcium nitrate
(0.25%), zinc sulfate (1%) + urea (0.5%), fermented sugar-
cane extract (2.8%), salicylic acid (1 or 3 mM), citric acid (5
mM), or 2,4-dichlorophenoxyacetic acid (2,4-D) (0.002%).
Results indicated that foliar treatment with 2,4-D reduced
fruit drop (2.6%) as compared to the control (15.2%). Fruit
decay was delayed and flavor improved by 5 mM citric acid.
Weight loss was reduced after 3mM salicylic acid applica-
tion, while methanol (0.13%), salicylic acid (1 and 3 mM)
and citric acid (5 mM) caused a delay in fruit coloring.
Numerical solution to the Complex 2D Helmholtz Equation based on Finite Volume Method with Impedance Boundary Conditions
Authors: Handlovičová Angela , Riečanová Izabela
Published: December 2016

In this paper, the numerical solution to the Helmholtz equation with impedance boundary condition, based on the Finite volume method, is discussed. We used the Robin boundary condition using exterior points. Properties of the weak solution to the Helmholtz equation and numerical solution are presented. Further the numerical experiments, comparing the numerical solution with the exact one, and the computation of the experimental order of convergence are presented.
Greek Lists of the Apostles: New Findings and Open Questions
Authors: Guignard Christophe
Published: December 2016

From the 4th/5th century on, one finds in virtually all the languages of early and mediaeval Christianity lists providing basic information about the apostles, which form a large and prolific tradition. Dealing with the Twelve (and Paul), and/or the seventy disciples of Luke 10, these lists bring together biblical and traditional or apocryphal data: for the Twelve and Paul, mainly the regions that they evangelised, their martyrdom and their burial place; for the Seventy, mainly their episcopal sees. Most of the major texts were edited by Theodor Schermann in 1907, but the apostle lists were afterwards largely neglected by scholars. Conceived as a preliminary report on a new research project on theses texts, this article deals with the identification of many new Greek witnesses, before focusing on two particular textual traditions on which the results attained so far shed new light: firstly, the
Remodeling of the Inner Hair Cell Microtubule Meshwork in a Mouse Model of Auditory Neuropathy AUNA1
Authors: Surel Clément , Guillet Marie , Lenoir Marc , Bourien Jérôme , Sendin Gaston , Joly Willy , Delprat Benjamin , Lesperance Marci M. , Puel Jean-Luc , Nouvian Régis
Published: December 2016

Auditory neuropathy 1 (AUNA1) is a form of human deafness resulting from a point mutation in the 5′ untranslated region of theDiaphanous homolog 3(DIAPH3) gene. Notably, theDIAPH3mutation leads to the overexpression of the DIAPH3 protein, a formin family member involved in cytoskeleton dynamics. Through study of diap3-overexpressing transgenic (Tg) mice, we examine in further detail the anatomical, functional, and molecular mechanisms underlying AUNA1. We identify diap3 as a component of the hair cells apical pole in wild-type mice. In the diap3-overexpressing Tg mice, which show a progressive threshold shift associated with a defect in inner hair cells (IHCs), the neurotransmitter release and potassium conductances are not affected. Strikingly, the overexpression of diap3 results in a selective and early-onset alteration of the IHC cuticular plate. Molecular dissection of the apical components revealed that the microtubule meshwork first undergoes aberrant targeting into the cuticular plate of Tg IHCs, followed by collapse of the stereociliary bundle, with eventual loss of the IHC capacity to transmit incoming auditory stimuli.
The Right Superior Frontal Gyrus and Individual Variation in Proactive Control of Impulsive Response
Authors: Hu Sien , Ide Jaime S. , Zhang Sheng , Li Chiang-shan R.
Published: December 2016

A hallmark of cognitive control is the ability to rein in impulsive responses. Previously, we used a Bayesian model to describe trial-by-trial likelihood of the stop signal or p(Stop) and related regional activations to p(Stop) to response slowing in a stop signal task. Here, we characterized the regional processes of conflict anticipation in association with intersubject variation in impulse control in 114 young adults. We computed the stop signal reaction time (SSRT) and a measure of motor urgency, indexed by the reaction time (RT) difference between go and stop error trials or “GoRT − SERT,” where GoRT is the go trial RT and SERT is the stop error RT. Motor urgency and SSRT were positively correlated across subjects. A linear regression identified regional activations to p(Stop), each in correlation with SSRT and motor urgency. We hypothesized that shared neural activities mediate the correlation between motor urgency and SSRT in proactive control of impulsivity. Activation of the ventromedial prefrontal cortex, posterior cingulate cortex and right superior frontal gyrus (SFG) during conflict anticipation correlated negatively with the SSRT. Activation of the right SFG also correlated negatively with GoRT − SERT. Therefore, activation of the right SFG was associated with more efficient response inhibition and less motor urgency. A mediation analysis showed that right SFG activation to conflict anticipation mediates the correlation between SSRT and motor urgency bidirectionally. The current results highlight a specific role of the right SFG in translating conflict anticipation to the control of impulsive response, which is consistent with earlier studies suggesting its function in action restraint.

SIGNIFICANCE STATEMENTIndividuals vary in impulse control. However, the neural bases underlying individual variation in proactive control of impulsive responses remain unknown. Here, in a large sample of young adults, we showed that activation of the right superior frontal gyrus (SFG) during conflict anticipation is positively correlated with the capacity of inhibitory control and negatively with motor urgency in the stop signal task. Importantly, activity of the right SFG mediates the counteracting processes of inhibitory control and motor urgency across subjects. The results support a unique role of the right SFG in individual variation in cognitive control.
Activation of Glutamatergic Fibers in the Anterior NAc Shell Modulates Reward Activity in the aNAcSh, the Lateral Hypothalamus, and Medial Prefrontal Cortex and Transiently Stops Feeding
Authors: Prado Luis , Luis-Islas Jorge , Sandoval Osvaldo I. , Puron Liliana , Gil Moreno M. , Luna Alvaro , Arias-García Mario A. , Galarraga Elvira , Simon Sidney A. , Gutierrez Ranier
Published: December 2016

Although the release of mesoaccumbal dopamine is certainly involved in rewarding responses, recent studies point to the importance of the interaction between it and glutamate. One important component of this network is the anterior nucleus accumbens shell (aNAcSh), which sends GABAergic projections into the lateral hypothalamus (LH) and receives extensive glutamatergic inputs from, among others, the medial prefrontal cortex (mPFC). The effects of glutamatergic activation of aNAcSh on the ingestion of rewarding stimuli as well as its effect in the LH and mPFC are not well understood. Therefore, we studied behaving mice that express a light-gated channel (ChR2) in glutamatergic fibers in their aNAcSh while recording from neurons in the aNAcSh, or mPFC or LH. In Thy1-ChR2, but not wild-type, mice activation of aNAcSh fibers transiently stopped the mice licking for sucrose or an empty sipper. Stimulation of aNAcSh fibers both activated and inhibited single-unit responses aNAcSh, mPFC, and LH, in a manner that maintains firing rate homeostasis. One population of licking-inhibited pMSNs in the aNAcSh was also activated by optical stimulation, suggesting their relevance in the cessation of feeding. A rewarding aspect of stimulation of glutamatergic inputs was found when the Thy1-ChR2 mice learned to nose-poke to self-stimulate these inputs, indicating that bulky stimulation of these fibers are rewarding in the sense of wanting. Stimulation of excitatory afferents evoked both monosynaptic and polysynaptic responses distributed in the three recorded areas. In summary, we found that activation of glutamatergic aNAcSh fibers is both rewarding and transiently inhibits feeding.

SIGNIFICANCE STATEMENTWe have established that the activation of glutamatergic fibers in the anterior nucleus accumbens shell (aNAcSh) transiently stops feeding and yet, because mice self-stimulate, is rewarding in the sense of wanting. Moreover, we have characterized single-unit responses of distributed components of a hedonic network (comprising the aNAcSh, medial prefrontal cortex, and lateral hypothalamus) recruited by activation of glutamatergic aNAcSh afferents that are involved in encoding a positive valence signal important for the wanting of a reward and that transiently stops ongoing consummatory actions, such as licking.