bluuebunny/crossref_metadata_2025 huggingface dataset:
The soil characteristics and morpho-physiological traits of two violet (Viola sp.) species as influenced by gibberellic acid and nitrogen
Authors: Nekouyar Neda , Naderi Roohangiz , Hashemabadi Davood , Torkashvand Ali Mohammadi
Published: February 2024

ABSTRACT Violet, with its pleasant scent and attractive flower color, is also important for its medicinal and edible uses, in addition to ornamental uses. Proper nutrition of the plant (violet) with essential nutrients and growth hormones improves the quantitative and qualitative characteristics and can increase the economic value and popularity of these flowers. In this regard, the current research aims to investigate the combined effect of nitrogen (N) and gibberellic acid (GA) on the morphophysiological traits of two native Iranian violet species (Viola tricolor and Viola odorata), as a factorial experiment with three factors including two species of violets, three levels of GA (0, 150 and 300 mg/L) and three levels of N (0, 100 and 200 mg/L) in a completely randomized design with 18 treatments, 3 replications and a total of 216 plants. Some characteristics of planting medium, morphophysiological traits and activity of antioxidant enzymes were evaluated. The results of ANOVA showed that the three-way effect of experimental treatments on all evaluated traits is significant. According to the results of comparing the averages the N application reduced the soil electrical conductivity (EC) versus its non-application in both violet species and at all GA levels. The highest soil N in both species was obtained from the application of 0 mg/L GA × 100 or 200 mg/L N. In two species of violets, the highest number of leaves, flowers, and stolons was obtained from the treatment of 300 mg/L GA × 200 mg/L N. The highest chlorophyll a and total chlorophyll among the treatments were related to V. odorata × 150 mg/L GA × 200 mg/L N. The application of GA and N in both species increased peroxidase activity versus the control. The highest level of this enzyme activity was related to 300 mg/L GA × 200 mg/L N. V. odorata had higher peroxidase activity than V. tricolor. The lowest and highest levels of catalase activity were recorded by control × V. tricolor (0.13 nM/g FW/min) and V. odorata × 300 mg/L GA × 200 mg/L N (0.676 nM/g FW/min), respectively. According to the results, with the application of 300 or 150 mg/L GA × 200 mg/L N, the ornamental and edible properties of these two types of violets are improved, and their economic value and marketability are increased, and there will be a change in the sales market of these flowers.
Forum on Rahul Rao’s Out of Time, Part I: Queer Mutations and Repressions
Authors: Maione Emerson , Quinalha Renan
Published: February 2024

Abstract In this Forum, six scholars reflect on Rahul Rao’s recent book Out of Time: The Queer Politics of Postcoloniality from other geographies, themes and radical possibilities. Part I offers dialogues with Out of Time from Trump’s USA and Brazil’s ‘hetero-military’ dictatorship and Portuguese colonial roots. Emerson Maione and Renan Quinalha explore how Rao’s elaborations of homonationalism, homocapitalism, homoromanticism and ‘pink-washing’ more generally travel in new contexts and how the ‘fetishization of law’ can mislead investigations of queer-, homo- and transphobias.
Forum on Rahul Rao’s Out of Time, Part III: Hopeful Lines? – Method and Style
Authors: Khalili Laleh , Chamon Paulo
Published: February 2024

Abstract In this Forum, six scholars reflect on Rahul Rao’s recent book Out of Time: The Queer Politics of Postcoloniality from other geographies, themes and radical possibilities. Part III explores the way Out of Time traces out its argument, focusing especially on Rao’s meaning-making, the care by which he makes distinctions and ambiguities, and the intimacy of his prose. In the first section, Laleh Khalili shows that generosity is key to the book’s method and style. Khalili takes Rao’s brief treatment of Freddie Mercury as emblematic of how Out of Time dwells in ambivalences and thematic echoes across its chapters. Chamon shows how disorientation remains a central question of the book, ‘but not only,’ since Rao also finds key ways to orient politics at the same time. In the second section, Chamon sensitively explores how Rao tries simultaneously to hold together multiple temporalities and permanences, mutations and grammars, and conviviality and oppositionality—all in order to understand how Rao’s lines of prose, first lines and last lines, exist in productive tension with the sovereign lines that make international politics possible.
Yield and physical-chemical quality of okra fruits irrigated with brackish water and phosphorus fertilization
Authors: Cruz Filho Elizeu M , Sousa Geocleber G de , Costa Francisco Hermeson R da , Sousa Henderson C , Silva Fred Denilson B da , Schneider Fernanda , Silva Ênio FF e , Leite Kelly N
Published: February 2024

ABSTRACT Phosphate fertilization can mitigate the deleterious effects of salts in the different stages of okra. The objective was to evaluate the effect of the cyclical use of water of lower and higher ECw at different phenological stages under phosphorus fertilization on productivity and fruit quality of okra. A completely randomized design was used, in a 4 x 3 factorial scheme, with four irrigation strategies of cyclical use with water of 0.3 dS/m (W1) and 2.0 dS/m (W2) applied in different phenological stages (IS1 = W1 throughout the cultivation cycle; IS2 = W2 in the establishment phase, W1 in the vegetative phase and W2 in the reproductive and maturation phase; IS3 = W1 in the establishment phase and W2 in the vegetative, reproductive and maturation phase; and IS4 = W1 in the establishment and vegetative phase, and W2 in the reproductive and maturation phase, with three doses of phosphorus (0, 50 and 100 kg/ha), and four replications. Cyclic water use of 0.3 dS/m in the establishment and vegetative phase and 2.0 dS/m in the reproductive and maturation phase reduced the thickness of the peel, while for the length of the fruit this reduction was evidenced with the use of water 0.3 dS/m throughout the cycle. Doses of 50 and 100 kg/ha provided greater performance in fruit quality and productivity of okra.
The expanding role of the curator ad litem i n protecting children's rights in South Africa
Authors: Hansungule-Nefale Zita M , Courtenay Morgan R
Published: February 2024

The appointment of the curator ad litem during litigation in which children's interests are concerned has, over the years, played a critical role in advancing the child's right to be heard and participate in matters affecting them for the advancement of their best interests. Prof Boezaart's seminal article on the role of the curator ad litem and children's access to the courts set out a comprehensive review of the origins, duties and role of the curator. Litigation and resultant court pronouncements subsequent to the article have continued to affirm the importance of the curator's role in matters dealing with the care of children; delictual matters in which children have legitimate financial claims; and acquisition of parental rights and responsibilities of the unborn child. The courts have affirmed the fact that the curator must only be appointed when their presence is necessary and not duplicate the functions of attorneys representing parents or caregivers of the children or the parents or caregivers themselves. The curator represents and protects the interests of the children concerned, prevents conflict with the interests of the parents, guardian or caregiver or represents the child when such parent, guardian or caregiver is unwilling to act in the interests of the child. The courts have held that in highly contested matters, the curator must, as an officer of the court, keep an open mind, remain neutral, and be open to all arguments in the interests of the children concerned. They must not allow themselves to be distracted by contentious issues in litigation and must honour their obligation to provide insight into the wishes and views of children and to apply their legal knowledge to the child's perspective. The curator has also played a critical role in protecting the interest of the unborn child by conducting an objective investigation and ensuring that their interests are fully before the court.
The status of nomination forms and wills when retirement funds' death benefits are distributed
Authors: Marumoagae Motseotsile Clement
Published: February 2024

This paper discusses the importance of deceased retirement fund members nominating their preferred beneficiaries to receive their accumulated retirement benefits when they die. It assesses whether nominations made by deceased members through nomination forms (and at times wills) are binding on retirement funds boards when distributing death benefits. It further assesses whether nominated beneficiaries are entitled to be allocated the available death benefits. Most importantly, this paper highlights the inherent weakness in section 37C of the Pension Funds Act 24 of 1956 regarding the treatment of nominated beneficiaries. It demonstrates that these beneficiaries are often requested to prove financial dependency despite this provision being silent on the issue. It illustrates further that the nominated beneficiaries' entitlement to be considered and allocated death benefits does not arise from financial dependency but from the act of nomination. It argues that there is no mechanism that retirement funds' boards can utilise to determine what should be allocated to the nominated beneficiaries. Furthermore, this paper argues that section 37 of the PFA is constitutional.
Öğretmenlerin Eleştirel Düşünme Eğilimleri ile Öğretim Programına Bağlılık Düzeyleri Arasındaki İlişkinin İncelenmesi
Authors: YURT Eyüp
Published: February 2024

Bu araştırmada, öğretmenlerin öğretim programına ne ölçüde bağlı olduklarını ve eleştirel düşünme eğilimlerinin bu bağlılık üzerindeki etkisini belirlemek amaçlanmıştır. Araştırma, korelasyon araştırması deseni temel alınarak yürütülmüştür. Araştırmanın çalışma grubunda, Marmara bölgesinin bir ilinde, 2022-2023 eğitim-öğretim yılında devlet okullarında görev yapan 357 öğretmen yer almıştır. Öğretim programına bağlılık ve California eleştirel düşünme eğilimi ölçekleri veri toplama aracı olarak kullanılmıştır. Betimsel analiz, Pearson korelasyon ve çoklu doğrusal regresyon analizi uygulanarak veriler analiz edilmiştir. Elde edilen verilere göre, öğretmenlerin öğretim programına bağlılıkları düşük düzeydedir. Öğretmenlerin resmî olarak sunulan öğretim programını izlemek yerine, öğretim programında çeşitli değişiklikler veya uyarlamalar yapma eğiliminde olduğu anlaşılmıştır. Ayrıca öğretmenlerin eleştirel düşünme eğilimleri ile öğretim programına bağlılıkları arasında negatif yönlü bir ilişki bulunmuştur. Eleştirel düşünme eğilimini oluşturan, doğruyu arama, açık fikirlilik, analitiklik, meraklılık, sistematiklik becerileri arttıkça öğretmenlerin öğretim programına bağlılığının azaldığı belirlenmiştir. Eleştirel düşünme eğilimine sahip öğretmenlerin öğretim programında daha fazla esneklik gösterebilme ve kendi özgün öğretim yöntemlerini öğretim sürecine yansıtabilme potansiyeline sahip olduğu anlaşılmıştır.
Ders Çalışma Süresi ve Sınav Başarısı Arasındaki İlişki: Sınav Kaygısının Düzenleyici Rolü
Authors: YAZICI DEMİR Yeliz , ATLİ Abdullah
Published: February 2024

Bu çalışmada, ders çalışma süresi ve sınav başarısı arasındaki ilişkide sınav kaygısının düzenleyicilik rolü incelenmiştir. Kesitsel bir tasarım kullanılan çalışmada 719 lise son sınıf öğrencisine (Ortyaş = 17.71) ulaşılmıştır. Veri toplama araçları olarak Sınav Kaygısı Ölçeği ile demografik bilgi ölçeği uygulanmıştır. Ayrıca düzenleyicilik rolünü araştırmak üzere katılımcıların en son girdikleri deneme sınavından aldıkları puanlar ve son altı ayda kaç dakika ders çalıştıkları ile ilgili bilgiler toplanmıştır. Verilerin analizinde SPSS programı kullanılırken, düzenleyicilik ilişkisini test etmek amacıyla Process Macro model 1 kullanılmıştır. Sonuçlar, ders çalışmaya ayrılan süre ile sınav başarısı arasında pozitif yönde ilişki olduğunu ve bu ilişkinin sınav kaygısı tarafından düzenlendiğini göstermektedir. Ders çalışma süresi ile sınav başarısı arasındaki bu pozitif ilişki sınav kaygısı düşük olanlarda daha yüksektir. Sınav kaygısı yüksek olan adayların daha az ders çalışma süresi olduğu ve bu durumun da dolaylı olarak sınav başarısını etkilediği görülmektedir. Elde edilen sonuçlar ışığında üniversiteye hazırlanan adayların, zaman yönetimi becerileri, kaygı ile baş etme becerilerine yönelik stratejiler tartışılmış ve literatür ışığında adaylara, öğretmenlere, anne-babalara ve ileride bu konuda yapılabilecek araştırmalar ile ilgili önerilerde bulunulmuştur.
Elektrifizierte Chemische Industrie
Authors: Förtsch Dieter , Kochenburger Thomas , Krämer Stefan
Published: February 2024

Die Umstellung von Anlagen der chemischen Industrie für eine nachhaltige und klimaneutrale Produktion stellt eine große Herausforderung dar. Allerdings ist die heutige Chemieindustrie nicht nur ein Teil des Problems, sie kann in Zukunft aufgrund ihrer Fähigkeiten auch ein großer Teil der Lösung sein. Zwischen dem Ist-Zustand und einem zukünftigen Idealzustand, in dem chemietechnische Anlagen nachhaltig im Zentrum einer klimaneutralen Kreislaufwirtschaft stehen, sind Zwischenschritte erforderlich. Einer dieser Zwischenschritte ist eine Produktion, die sowohl energie- als auch materialeffizient operiert, so dass die Emission von Treibhausgasen weitestgehend minimiert ist. Die Elektrifizierung von Bestands- und Neuanlagen wird dabei eine große Rolle spielen. Dieser Beitrag skizziert, welche Möglichkeiten für eine Elektrifizierung sinnvoll erscheinen und erläutert an einem Beispiel, welchen Einfluss dies auf die Komplexität der Automatisierung hat.
Prozessautomatisierung zur Erhöhung der Sustainability
Authors: Seibl Felix , Haut Ralf
Published: February 2024

Der ZVEI-Arbeitskreis „Prozessautomatisierung für Sustainability“ unter Leitung von Ralf Haut bearbeitet schon seit Jahren die Frage, wie die Prozessautomatisierung entscheidend zur Nachhaltigkeit in der Prozessindustrie beitragen kann. Auf Seiten der NAMUR wurde bereits im Jahr 2012 das NAMUR-Arbeitsblatt NA 140 zum Beitrag der Automatisierungstechnik zur Steigerung der Energieeffizienz erstellt. Eine 60 Seiten umfassende Broschüre „Sustainability durch Prozessautomation“ wurde in Zusammenarbeit der beiden Verbände erstellt und auf der NAMUR-Hauptsitzung 2023 vorgestellt (Download siehe [1]). Sowohl die Energie- als auch die Klimakrise machen deutlich, dass jetzt alle Möglichkeiten zur Steigerung von Effizienz und Nachhaltigkeit genutzt werden müssen. Dieser Beitrag gibt einen Überblick über den Inhalt der Broschüre und will damit eine schnelle und gute Umsetzung anregen. Eine englische Übersetzung der Broschüre ist für Anfang 2024 geplant.
Traumatic injury of vertebral artery complicated by formation of a giant pseudoaneurysm of the V3 segment (clinical observation and literature review)
Authors: Ayrapetyan A. A. , Gromov D. G. , Papoyan S. A. , Smyalovskiy D. V. , Asaturyan K. S. , Starikov S. S. , Zaytsev A. D. , Tavlueva E. V.
Published: February 2024

Traumatic vertebral artery injury (TVAI) is a rare but severe pathology which can be associated both with penetrating injury of the neck and blunt or unclassified injury. Injury of the vertebral artery, especially due to gunshot or knife wounds, causes severe condition of the patients, development of a wide spectrum of complications including life-threatening, high rates of disabilities and mortality.

There is no consensus on the treatment tactics for this pathology. Open surgery as the first stage of surgical intervention can be used in a limited number of cases. X-ray endovascular techniques of TVAI treatment are considered to be preferable.

We present a clinical case of a 27‑year-old patient with TVAI caused by a penetrating gunshot wound of the neck and complicated by formation of a giant pseudoaneurysm of the V3 segment of the vertebral artery. Two-stage combination treatment of TVAI was performed using endovascular and open surgical techniques.

Descriptions of TVAI cases are rare, and further accumulation and analysis of corresponding data and proposals on treatment of the patients with TVAI will help to formulate precise algorithms of doctors’ actions and optimize treatment tactics.
Technique for intraoperative monitoring of corticospinal tract integrity using an electrode with a dynamic balloon
Authors: Krylov V. V. , Lukianchikov V. A. , Gorozhanin V. A. , Barbakadze Z. A. , Sinkin M. V.
Published: February 2024

Aim. To present a technique for continuous monitoring of corticospinal tract integrity using an electrode with a dynamic balloon, examine the advantages and disadvantages of the selected and alternative monitoring techniques.

Materials and methods. At the 1st stage, an electrode combined with a dynamic balloon was prepared. At the 2nd stage, continuous monitoring of the corticospinal tract using direct stimulation of the cortex using ballon grid during the main stage of cerebral surgery was performed. At the 3rd stage, interpretation of the obtained neurophysiological responses was performed.

Results. The presented technique of continuous monitoring of the integrity of the corticospinal tract through direct cortical stimulation using the developed device prevents false response decreases which significantly helps with the interpretation of the obtained results and increases information value of the technique. The described technique is based on the presented clinical observations of intracerebral tumor resection, as well as microsurgical aneurysm clipping using the technique. During surgery, no false decrease of the neurophysiological signal amplitude was observed due to dynamic ballon inflation and maintenance of close contact between the electrode and the surface of the brain. A surgery performed using this technique allowed to achieve a favorable neurological outcome in a patient in the postoperative period.

Conclusion. The presented device allows to perform continuous neuromonitoring using direct cortical electrostimulation with a strip electrode at any level of brain retraction. The technique decreases the risk of primary and secondary injury of the corticospinal and corticobulbar tracts which increases safety of neurosurgical intervention and decreases risks of neurological complications.
Enfermagem em Prática Avançada no pronto atendimento: uma reflexão promissora
Authors: Araújo Francielli Aparecida , Amorim Ana Paula Moreira , Goulart Maihê Carvalho Lemos e
Published: February 2024

Refletir acerca das Unidades de Pronto Atendimento 24h como cenário de atuação para Prática Avançada de Enfermeiros nos serviços de urgência e emergência tem sido muito importante. A Enfermagem de Prática Avançada é uma especialidade em que atuam enfermeiros com conhecimento ampliado e habilidades adicionais, são capazes de tomar decisões complexas, além de possuírem nível avançado de práticas clínicas especificas. Os serviços de urgência e emergência são cenários promissores para o desenvolvimento da Enfermagem de Prática Avançada, incluindo as Unidade de Pronto Atendimento 24h, especialmente pela capacidade de atendimentos de alta complexidade e atuação de profissionais altamente capacitados. Portanto, há necessidade de reflexão sobre os avanços e entraves na atuação e regulamentação, sobretudo no que se refere a este cenário, pouco discutido neste contexto da Enfermagem de Prática Avançada no Brasil. Conclusão: Existe grande necessidade de ampliação da discussão da Enfermagem de Prática Avançada para os demais níveis de atenção no Brasil. Há serviços com amplo potencial a serem desenvolvidos, sendo um deles as Unidades de Pronto Atendimento 24h, observa-se que o enfermeiro de práticas avançadas nestes serviços poderá trazer grandes benefícios para a população, além de melhorar a qualidade da assistência, trazendo maior autonomia para os enfermeiros destes serviços.
NUMERICAL INVESTIGATION OF THE VALVE MODEL FOR PRIMARY SUTURELESS IMPLANTATION
Authors: Klyshnikov Kirill Yu. , Ovcharenko Evgeny A. , Onishchenko Pavel S. , Glushkova Tatyana V. , Kostyunin Alexander E. , Rezvova Maria A. , Barbarash Olga L.
Published: February 2024

Highlights

The presented numerical model of the bioprosthesis support frame for sutureless fixation needs to be optimized to reduce the amplitude of the von Mises stresses.

The presented setup of numerical modeling has been validated using the study of commercial analogs.

 

Abstract

Aim. To assess the stress-strain state of three computer models of TAVI prosthesis support frames during crimping and shaping to the delivery configuration.

Methods. The study included three models of stent-like support frames for balloon-expandable devices, which are intended to serve as a foundation for the subsequent development of a domestic aortic valve prosthesis: two models of commercial bioprostheses and one experimental. The objects were evaluated numerically under the conditions of stress-strain state that arises in the stent support frames, simulating two loads: crimping and shaping to the delivery configuration. The study was conducted using the numerical modeling complex Abaqus/CAE (“Dassault Systemes”, France). The key indicators for evaluation were the von Mises stress, as a strength criterion, and its distribution over the frame; the presence and proportion of elastic recoil.

Results. It was shown that all samples are capable of reaching the required diameter without excessive material. A quantitative investigation of the Von Mises stress showed that commercial models display amplitudes below the material`s strength limit (892.4 and 916.8 MPa), whereas the proprietary model exceeds this limit, reaching 991.4 MPa, requiring geometry optimization. Shaping to the delivery configuration indicates that all models provide safe expansion up to 26 mm, with a Von Mises stress level in the range of 882.4–914.1 MPa, which is below the strength limit of the cobalt-chrome alloy. Moreover, we have noted heterogeneous stress distribution, with concentration in the lamella junction areas.

Conclusion. Thus, it has been demonstrated that numerical modeling and the finite element method can be effectively applied to assess the stress-strain state of sutureless prostheses. Geometry optimization and further development of this project – the development of a Russian minimally invasive aortic valve prosthetic system, may contribute towards increasing the accessibility of this treatment method.
FEATURES OF POLYURETHANE MATRIX REMODELING IN SHEEP MODEL EXPERIMENTS
Authors: Antonova Larisa V. , Velikanova Elena A. , Senokosova Evgeniya A. , Mukhamadiyarov Rinat A. , Krivkina Evgeniya O. , Koshelev Vladislav A. , Mironov Andrey V. , Shabaev Amin R. , Sardin Egor S. , Prokudina Ekaterina S. , Khanova Maryam Y. , Barbarash Leonid S.
Published: February 2024

Highlights

The article describes the features of remodeling of polyurethane matrices during long-term implantation into the vascular bed of sheep. The results indicate high biocompatibility of polyurethane and resistance to bioresorption. The obtained data are significant for the development of medical products for cardiovascular surgery, in particular, biodegradable vascular prostheses.

 

Abstract

Aim. To evaluate the features of polyurethane remodeling in a long-term experiment on a large animal model.

Methods. Matrices made of 12% polyurethane solution in chloroform were manufactured by electrospinning at the Nanon-01A nanofiber electrospinning system (MIC, Japan). Matrix samples in the form of patches were implanted into the carotid arteries of sheep (n = 3) for a period of 6 months. The patency of vessels with implanted matrices was assessed after 2, 4 and 6 months using a portable hand-carried color Doppler - M7 Premium Ultrasound Machine (Mindray, China). The structure of the matrix surface before and after implantation was studied using an S-3400N scanning electron microscope (Hitachi, Japan). Histological examination of the explanted samples was carried out using an AXIO Imager A1 microscope (Carl Zeiss, Oberkochen, Germany) with previous staining of matrix sections with hematoxylin-eosin, Van Gieson and alizarin red C. Data processing was performed using the Statistica 6.0 software.

Results. After 2, 4 and 6 months of implantation of polyurethane matrices into the carotid artery of sheep, complete patency of the carotid arteries was revealed. Macroscopically, after 6 months of implantation, the matrix completely resembled the carotid artery wall due to the full consolidation of the matrix with the artery wall and remodeling. Layers of newly formed vascular tissue – neointima and neoadventitia – were formed on the basis of the matrix. Histological examination revealed the structural integrity of the matrix without signs of inflammation and calcification both in the matrix structure and adjacent tissues.

Conclusion. The biological inertia of polyurethane matrices with signs of remodeling was noted, which indicates a high biocompatibility of the material. Resistance to bioresorption and the ability to keep the frame of the product for a long time allows us to consider polyurethane as a suitable material for the formation of anti-aneurysmal protection of biodegradable vascular prostheses.
PATHOGENIC MECHANISMS OF HEART FAILURE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS
Authors: Ivanchenko Vera S. , Gagarina Alina A. , Goryanskaya Irina Ya. , Soldatova Olga V. , Ushakov Alexey V.
Published: February 2024

Highlights

The review presents up-to-date data on the contribution of type 2 diabetes mellitus to the development and progression of heart failure. The review highlights the key mechanisms of the pathogenesis of heart failure associated with changes in the energy metabolism of cardiomyocytes.

 

Abstract

Type 2 diabetes mellitus is one of the main risk factors that significantly worsen the prognosis of heart failure and increases the probability of fatal cardiovascular events. The development of heart failure in diabetic patients involves a great number of risk factors for the rapid progression of atherosclerosis, as well as numerous combinations of neurohumoral, molecular and histological changes not associated with atherogenesis, which interconnection results in cardiovascular complications and heart failure decompensation. This review discusses the key mechanisms underlying development of heart failure in type 2 diabetes mellitus, in particular, special attention is paid to cardiomyocyte energy metabolism, cardiomyocyte death, and the significance of epigenetic factors in progression of chronic heart failure.
BIODEGRADABLE ANTI-ADHESIVE MEMBRANES WITH ANTIBACTERIAL PROPERTIES FOR USE IN SURGERY
Authors: Kudryavtseva Yulia A. , Kanonykina Anastasia .Yu. , Shishkova Daria K. , Efremova Natalia A. , Onishchenko Pavel S. , Barbarash Leonid S.
Published: February 2024

Highlights

Adhesion formation is a classic complication of any surgical intervention, which reduces the quality of life of patients and carries the risk of fatal complications during repeated surgery. Moreover, there is an issue of postoperative wound infection. Currently, there are no effective anti-adhesive agents with antibacterial activity in the arsenal of surgeons.

 

Aim. To justify and develop biodegradable anti-adhesive membranes with antibacterial activity.

Methods. The membranes were made by electrospinning using a composition of biodegradable polymers: polylactide-co-glycolide copolymer (50:50) Mm 20–30 KDa and ε-caprolactonone. The antibiotic Tigacil was added to the polymer solution to impart antibacterial properties to the membrane. The surface structure of the membranes was evaluated using a scanning electron microscope. Physical, mechanical and hemocompatibility properties were studied. The antibacterial activity of the membranes was evaluated after manufacturing, sterilization and storage for 24 months.

Results. The inclusion of Tigacil in the membrane composition contributed to a decrease in fiber thickness by almost 4 times, while the packing of fibers became denser, which affected the increase in the strength of the modified membranes. Samples of membranes before and after the inclusion of Tigacil have no negative effect on erythrocytes The obtained results confirm the antibacterial activity of membranes against Staphylococcus aureus and Klebsiella pneumoniae, as well as the preservation of these properties after sterilization and during 2 years of storage.

Conclusion. The inclusion of Tigacil in the polymer composition makes it possible to create biodegradable anti-adhesive membranes with antibacterial activity, which is maintained for two years after the manufacture. The inclusion of Tigacil in the polymer fiber composition does not adversely affect the initial properties of the membrane.
To the problem of medical-forensic procedure of remote examination of living persons: a scientific review
Authors: Badanova Anna N. , Begaliyev Yernar N. , Shabanov Vyasheslav B. , Seraliyeva Aliya M. , Shayakhmetova Zhanna B.
Published: February 2024

This article describes the aspects of conducting a remote medical examination. The norms of the criminal procedure legislation of Kazakhstan and foreign countries regulating the procedure for conducting medical examinations, remote investigative actions, and scientific publications of researchers in the field of medicine are considered. A literature review on the study topic revealed studies of scientists on aspects of conducting medical examinations, problems arising during their production, and a description of individual medical cases conducted remotely and noted the lack of comprehensive holistic studies, including an algorithm of actions, the legal basis for conducting a medical examination in a remote format, and the practical advantages of their production.
Considering the generalization of scientific works and analysis of domestic and foreign legislation on the subject, the authors propose an algorithm for conducting medical examinations in an online format. In the present work, a SWOT analysis of remote medical examinations was performed, and the positive and negative aspects of the introduction of remote medical examinations were determined. The trends and risks of their implementation in practice are considered.
Based on the analysis of the national mechanism for conducting medical examinations and research and adaptation of the norms of foreign legislation on the issue under consideration, proposals have been formulated to improve the steps of medical examinations. The proposed algorithm for conducting remote medical examinations will allow solving some practical problems, which will significantly increase the efficiency of their production.
O Seminario de Estudos Galegos: laboratorio dun plan pedagóxico para Galiza
Authors: Costa Rico Antón
Published: February 2024

O Seminario de Estudos Galegos, fundado en 1923, constituiuse en importante plataforma cultural galeguista, entre os anos 1928 a 1936, momento no que foi clausurado polas novas autoridades franquistas. Con máis de 170 socios activos, o SEG abriu diversas parcelas de estudo da realidade social, histórica, económica, e cultural de Galicia, o que se expresou nalgúns moi notables traballos de investigación, en xeiras de difusión cultural, no intercambio científico e de información con entidades académicas españolas e internacionais e na edición de libros. No SEG participaron algúns profesores atentos á problemática educativa de Galicia, e a través da Sección de Pedagogía, desde 1933, desenvolveron varias iniciativas. É o que se analiza na presente contribución, situando as súas achegas, tanto no panorama das demandas de reforma educativa española, como no contexto das orientacións educativas trazadas pola corrente ideolóxica do galeguismo. A Sección poderia ter sido um Laboratório de pensamento educativo, pero de facto non chegou a selo, e procúranse aqui as oportunas explicacións.
Sanchidrian, C., Ruiz Berrio, J. (coords.) (2010), Historia y perspectiva actual de la educación infantil
Authors: Costa Rico Antón
Published: February 2024

SANCHIDRIAN, C., RUIZ BERRIO, J.(coords.) (2010), Historia y perspectiva actual de la educación infantil
Use of inhaled nitric oxide in COVID-19
Authors: Nguyen H. C. , Pozdnyakova D. D. , Baranova I. A. , Chuchalin A. G.
Published: February 2024

Inhaled nitric oxide (iNO) is being considered as a potential therapeutic intervention for COVID-19 and post-COVID syndrome due to its various mechanisms such as vasodilation, antiviral activity, antithrombotic and anti-inflammatory effects. There is currently a lack of information on patient selection criteria, optimal dosing, duration and timing of administration, and methods of administration. These factors are of substantial importance for the efficacy of iNO therapy.Aim. To discuss the physiological basis of using inhaled nitric oxide for treating patients with COVID-19 and post- COVID syndrome, analyze the research findings, and present the achievements in nitric oxide synthesis technology in medicine.Conclusion. The early initiation and use of high-dose iNO appears to be an effective and safe treatment strategy for patients with COVID-19, as it targets the basic pathological mechanisms of the disease. iNO may also be a promising therapeutic option for patients with post-COVID syndrome. However, the optimal dosing regimen, continuous or intermittent, warrants further investigation. Recent advances in nitric oxide synthesis technology are of great significance for the broad practical application of iNO therapy.
Sex difference effects of acute starvation on excitatory and inhibitory synapses on dopamine neurons
Authors: Arshad Shazia Haque , Singh Ajay Kumar , Prasad Dayanand , Kumari Sarbil
Published: February 2024

Background: The aim of this study is to assess the influence of acute fasting on synaptic properties in the ventral tegmental area (VTA) with regards to the sex-dependent differences by use of male and female mice. The study aimed to unravel the intricate interplay between fasting, synaptic plasticity, and behavioural changes to enhance our understanding of the underlying mechanisms.
Methods: This study carried out at a tertiary care centre, employed a 16-hour overnight fasting protocol in female rodents and male rodents to examine the effects on physiological parameters, feeding behaviour, and neuronal attributes in the VTA. Various assays, including measurements of blood glucose, ketones, corticosterone (CORT) levels, locomotor activity, and electrophysiological recordings of synaptic currents, were conducted to assess the physiological and synaptic responses to acute fasting.
Results: The study found that acute fasting induced significant metabolic changes, including body mass decrease by about 10%. Altered food-seeking behaviour was evident, with male mice exhibiting a pronounced increase. Moreover, neuronal attributes in the midbrain or VTA showed gender-dependent responses: males displayed substantial 20% increase in the frequency of mEPSC onto the dopaminergic neurons in the midbrain post fasting, while females exhibited a 13% elevation in CORT levels, accompanied by a transient period of depression at stimulatory synapses onto dopaminergic neurons which was mediated by endocannabinoids. Notably, no significant changes were observed at restraining synapses in rodents of both genders. These findings highlight the nuanced influence of short-term fasting/starvation on the VTA's synaptic plasticity, emphasizing sex-specific responses and providing valuable insights into potential mechanisms influencing gender differences in neuropsychiatric conditions.
Conclusions: The study reveals that acute fasting induces sex-specific synaptic changes in the VTA, shedding light on the intricate relationship between metabolism, food-seeking behaviour, and neural plasticity. These findings emphasize the importance of considering gender-specific responses in studies exploring the neurobiological effects of fasting and their relevance to mental health.
First Record of Parasphaerosyllis malimalii (Polychaeta: Syllidae) from Gorgona Island (Colombian Pacific)
Authors: Londoño-Cruz Edgardo , Cardona-Gutiérrez María Fernanda , Londoño-Mesa Mario H.
Published: February 2024

A new species of polychaete, Parasphaerosyllis malimalii (Syllidae), inhabiting coral colonies of Pocillopora spp. was described on Coiba Island (Pacific coast of Panama) by Capa et al. (2001a). To improve its description and provide additional ecological remarks, 73 specimens of P. malimalii, found in dead fragments of Pocillopora spp. in two research projects on bioerosion in Gorgona Island (Colombian Pacific coast), between March 1998 and December 1999, and June 2015 and August 2018, were examined and measured. The average (±SD) length (in mm) of the specimens from the first (n=38) and second (n=35) projects were 2.84 (0.42) and 8.86 (3.24) respectively. The largest specimen was collected in the second project and measured 15.4 mm. The pygidium of this species has a pair of cirri slightly thicker and longer than the parapodial cirrus. These polychaetes are mostly dead coral inhabitants, nesting in vacant galleries left by borers. With this record, the distribution range of P. malimalii is extended southward to Gorgona Island. We are confident that this species must inhabit other coral reefs in the area, so we propose that the distribution of this species must be circumscribed to the Tropical Eastern Pacific.
Obtención y caracterización estructural de β-D-glucanos de la seta comestible Pleurotus pulmonarius
Authors: García-Cuan Aracely del Carmen , Gutiérrez-De Aguas Ricardo , Molina-Velasco Daniel R. , Silvera-Redondo Carlos
Published: February 2024

Se describe aquí el proceso de extracción, aislamiento y purificación para obtener un extracto crudo de β-D-glucanos de la seta comestible Pleurotus pulmonarius. A partir de una mezcla de micelio y cuerpos fructíferos del hongo (basidiocarpóforo), se preparó el extracto crudo, del cual se extrajeron β-D-glucanos en fracción acuosa y alcalina. El extracto crudo en fracción alcalina se purificó por diálisis. En la muestra de la mezcla de micelio y cuerpos fructíferos de la seta se detectaron los β-D-glucanos mediante las técnicas de espectroscopía infrarroja por transformada de Fourier y resonancia magnética nuclear de 1H y 13C. Se confirmó la triple hélice característica de su estructura con el método espectrofotométrico del rojo Congo. Los resultados mostraron que los β-D-glucanos representaban el 32,5 % (p/p) en la seta y el 17,10 % (p/p) en el micelio. Se concluyó que la metodología utilizada para la extracción fue eficaz, al confirmarse la presencia de β-D-glucano en un porcentaje elevado en el hongo P. pulmonarius.
WORK VALUES AND ATTITUDES TOWARD THE TECHNOLOGY OF GENERATION Z IN BRAZIL AND GERMANY
Authors: Münz Celine , Mascena Keysa Manuela Cunha de
Published: February 2024

Objective: The aim of this study was to analyze the differences related to work values and attitudes toward the technology of Generation Z in Brazil and Germany. Method: The proposed hypotheses were tested in a survey of 122 Brazilian and German participants. The data were analyzed using t-test and logistic regression models. Main Results: The results present differences between Brazilian and German Generation Z, challenging the literature that analyzes Generation Z as a global generation and reinforcing cultural differences between nationalities. The Brazilian sample presents more instrumental and prestige work values and is more positive and less negative regarding technology than the German sample. Relevance/Originality: The paper’s contribution provides evidence of Generation Z’s differences according to nationalities relevant to shaping their relationship with work and technology. The analysis of both constructs is interesting nowadays because of their interrelationship and the current changes in global work boundaries. Theoretical/Methodological Contributions: The literature predominantly presents that Generation Z is a global generation. Comparing participants from two countries with different levels of development provides an insight into their differences regarding work values and attitudes, which can be valuable for business management literature. Practical/Social Contributions: Recommendations for businesses are provided to improve attraction and retention strategies to tackle the shortage of skilled workers. This implies management strategies for firms with multicultural teams.
A Syntactic Proof of the Decidability of First-Order Monadic Logic
Authors: Orlandelli Eugenio , Tesi Matteo
Published: February 2024

Decidability of monadic first-order classical logic was established by Löwenheim in 1915. The proof made use of a semantic argument and a purely syntactic proof has never been provided. In the present paper we introduce a syntactic proof of decidability of monadic first-order logic in innex normal form which exploits G3-style sequent calculi. In particular, we introduce a cut- and contraction-free calculus having a (complexity-optimal) terminating proof-search procedure. We also show that this logic can be faithfully embedded in the modal logic T.
Zintegrowana ocena stanu hydrochemicznego doliny rzecznej w obszarze podmiejskim na przykładzie Strugi Dobieszkowskiej (Młynówki) (gm. Stryków)
Authors: Ziułkiewicz Maciej , Fortuniak Anna , Górowski Jan , Ajzert Mateusz , Kaźmierczak Kacper , Lik Kacper , Mytkowska Natalia , Ślisarczyk Tomasz
Published: February 2024

W pracy przestawiono wyniki badań wód występujących w jednej z najsilniej uźródłowionych dolin rzecznych na obszarze Wzniesień Łódzkich, tj. Strugi Dobieszkowskiej (Młynówki) – największego dopływu górnej Moszczenicy. Prace badawcze objęły, poza wodami źródlanymi, wody cieku i jego strefy hyporeicznej. Zrealizowano je w ciągu jednego dnia, dzięki czemu uzyskano zintegrowany obraz chwilowego stanu wód na obszarze trwającej od kilku dziesięcioleci presji antropogenicznej, związanej z postępującą urbanizacją podłódzkich wsi. Termin badań poprzedzony był długim okresem bezdeszczowym, stąd też przyjęto założenie, że badane środowiska będą reprezentować zasilanie podziemne. Dokonano oceny mieszania wód rzecznych i gruntowych pod dnem Strugi Dobieszkowskiej celem hydrochemicznej weryfikacji istnienia tam strefy hyporeicznej, gdyż wskazywały na to wyniki pomiarów pionowego gradientu hydraulicznego (VHG). Wykazano ogólne pogorszenia stanu hydrochemicznego wód w efekcie dopływu zanieczyszczeń, w tym poprzez strefę hyporeiczną. Porównanie trzech badanych środowisk wodnych wskazało zakres elementów hydrochemicznych, które istotnie je różnicują.
V Congreso Internacional de Desarrollo Universitario
Authors: Zambrano Carlos Edison , Díaz Ocampo Eduardo , Miñan Moyano Johnny , Acosta Gonzáles Génesis
Published: February 2024

El Congreso Internacional de Desarrollo Universitario (CIDU), viene posicionándose como una fiesta anual de la ciencia que es esperada con ansiedad por la comunidad académica de la Universidad Técnica Estatal de Quevedo y por diversas universidades, institutos, colegios, empresas y profesionales de diversas partes del mundo. El 2023 ha sido un año memorable para la ciencia, por ejemplo con avances en la terapia genética para combatir el cáncer, la inteligencia artificial cuántica para atender problemas en áreas como la criptografía, el descubrimiento de más de 500 nuevas especies de vida marina, la nave espacial Horizonte Rojo que sienta las bases para la colonización de Marte y el uso de una lengua artificial con la que se ha determinado que la excitación que produce el chocolate es mayor que la de un beso apasionado. En Ecuador se han liberado nuevas semillas y plantas, así como técnicas para su manejo, en ese contexto, el presente congreso tuvo por objetivo: Promover la difusión de avances científicos multidisciplinares de docentes, profesionales y estudiantes en ciencias agrarias, pecuarias, ingeniería, industria y producción, empresariales, sociales, económicas, financieras, salud y educativas. Los pasos metodológicos para desarrollar el CIDU partieron de la conformación del Comité de Honor con las tres principales autoridades de la UTEQ, luego el Comité Organizador compuesto por Decanos y especialmente el Comité Científico que llevó adelante el proceso de cada simposio. Un aspecto relevante constituyó el soporte logístico del personal técnico de la Dirección de Investigación, el material divulgativo elaborado por la Dirección de Relaciones Públicas, TICs y moderadores de simposios. El siguiente paso fue la selección de la modalidad y líneas de investigación, seguidamente se establecieron los criterios de participación, el registro en la página WEB y envío de trabajos. Paralelamente fueron publicadas las fechas de recepción de ponencias, notificación de aceptación y desarrollo del congreso, que estará caracterizado por un ambiente de reflexión, discusión, presentación de enfoques, planteamientos de manera abierta y democrática. En este año se tuvieron 14414 inscritos, cuatro conferencias magistrales presenciales, 80 conferencias magistrales virtuales y 593 ponencias de resultados de investigación, exposición de carteles, conversatorios y un curso de proyectos de investigación de manera presencial. Se trata en consecuencia de una modalidad que articula lo hibrido entre el espacio y el ciberespacio modalidades de sustentación y debates de científicos que provienen de 16 países del mundo y de casi todas las provincias del Ecuador. Las MEMORIAS DEL V CONGRESO INTERNACIONAL DE DESARROLLO UNIVERSITARIO, recogen las ideas, propuestas y debates de alta calidad científica tratadas del 06 al 08 de diciembre del 2023.
Influence of Packaging Materials and Size on Shelf Life and Quality of White Button Mushroom during Storage
Authors: Attri B.L. , Srivastava Anuradha , Kamal Shwet , Sharma V.P.
Published: February 2024

Background: Because of porous fruit body, high moisture content and extremely high respiration rate, the postharvest shelf life of button mushroom is a bottleneck in the mushroom industry as very high losses are recorded during transportation and marketing if the produce is not handled properly. Methods: NBS-5 strain of white button mushroom was treated with 0.05% potassium meta-bisulphite (KMS) followed by packing in 200, 400, 600, 800 and 1000 g capacity polyethylene (PE) and polypropylene (PP) bags of 150 gauge along with 0.01% vents. Dipping in water and packing in 200 g capacity bags was used as control. The packed mushrooms were stored at ambient (24-25°C and 58-62% RH) and low (4-6°C and 80-82% RH) temperature. Result: A significant increase in PLW (%) was recorded in all the treatments both at ambient and low temperature during storage but the increase was faster at room than refrigerated conditions. The white button mushroom in PE had a shelf-life of 7 and 16 days whereas it was 3 and 7 days, respectively, at ambient and low temperature storage conditions in control. A significant reduction in protein, sugars and phenols was recorded whereas polyphenol oxidase (PPO) increased notably during storage. Pack sizes of 200 and 400 g had an edge over 600, 800 and 1000 g with higher shelf-life at both storage conditions. PE packing was found comparatively better for extension of shelf-life compared to PP. The overall acceptability of button mushroom was also found better in 200 g and 400 g packing. The study revealed that the postharvest shelf-life of white button mushroom var. NBS-5 can be extended up to 16 days by packing in 200 and 400 g packs of PE stored at low temperature after pre-treatment of KMS.