bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALYSIS OF COMPANY PERFORMANCE AS ISSUERS BASED ON THE COMPASS 100 INDEX ON MARKET PRICES
Authors:   Dewa Putu Yohanes Agata L Sandopart, University of Pancasila, Indonesia., a Oleh
Published: June 2021

The background of this research is the desire of investors and issuers so that the individual stock price index continues to increase in the Indonesian stock market, in fact, fluctuates where investment stores and previous studies have stated the influence between company performance variables, investor expectations, investment risk on market prices and their impact on the index individual share price The research objective is to give investors confidence to invest in the Indonesian stock market by analyzing the effect of company performance, investor expectations, investment risk on market prices, and their impact on the individual stock price index. The sampling technique used is a nonprobability sampling from the Indonesia Stock Exchange data from September 2015- May 2018 with the Kompas Index 100 as an index of 100 liquid companies which is one of the references for investors to invest, the Analysis Technique uses Structural Equation Modeling (SEM) with the approach WarpPLS The research results concluded Company performance has a direct effect on market prices and has an indirect effect on the individual stock price index through market prices, investor expectations do not have a direct effect on market prices but have an indirect effect on the individual stock price index through market prices, investment risk does not directly affect market prices but indirect effect on the individual stock price index through market prices and market prices have a direct effect on the individual stock price index.
Solar disinfection of turbid hygiene waters in Lexington, KY, USA
Authors: Amirsoleimani Atena , Brion Gail M.
Published: June 2021

Solar disinfection (SODIS) could be a key to providing a clean, hygiene water for birthing uses, but the recommended climate zone is limited, the microbial indicators are related to gastrointestinal illness and not wound infections. SODIS feasibility was investigated to remove Escherichia coli from turbid water at temperatures less than 50 °C in Lexington, KY. Increasing turbidity from 0 to 200 NTU decreased E. coli inactivation from 5 to 1 log. With the same experimental protocol, more than 4-log inactivation of Staphylococcus aureus and Staphylococcus epidermidis (common human-skin microorganisms related to serious post-partum infections of both mother and child) was achieved at different turbidity levels with a maximum, in-bottle temperature of 49.2 °C after 5.5 h. The thermal inactivation of the bacterial indicators was assessed without UV radiation and turbidity in water at 37 and 47 °C. Skin bacteria were inactivated completely after 9.5 h at 47 °C, but only 58% removal happened for thermo-tolerant E. coli. These results suggest that SODIS application may be expanded geographically to treat water for hygiene purposes. However, as E. coli is also capable of causing wound infections, UV with thermal inactivation may be required to produce safe hygiene water by SODIS outside of recommended latitudes.
Methods of Random Mutagenesis of Aspergillus Strain for Increasing
Kojic Acid Production
Authors: Suryadi Herman , Irianti Marina Ika , Septiarini Tri Hastuti
Published: June 2021

Kojic acid is an organic acid that is commonly used in the pharmaceutical and cosmetic
industries. This acid compound is a secondary metabolite produced by various microorganisms, one
of which is Aspergillus oryzae. Typically, improving the strain can enhance kojic acid production. A
mutation is one of the tools to perform strain improvement because the change in kojic acidproducing
genes effectively increases kojic acid yield. A random mutagenesis is a classic approach
for inducing and producing mutants with random mutations. The mutagenesis can be generated by
the individual physical and chemical mutagen, combined physical and chemical mutagens, or initiate
by protoplast preparation. Aspergillus strains that are exposed to physical mutagens (e.g., UV) or
chemical mutagens (e.g., N-methyl-N-nitro-N-nitrosoguanidine (NTG)) showed their abilities in
increasing kojic acid production. Several new mutation methods, such as Ion Beam Implantation and
Atmospheric and room temperature plasma (ARTP), also showed good responses in enhancing the
production of biological products such as kojic acid. This review compared different random mutagenesis
methods of Aspergillus strain with various mutagen types to provide better insight for researchers
in choosing the most suitable method to increase kojic acid production.
TURNOVER INTENTION AMONG LECTURERS IN PRIVATE HIGHER EDUCATION: THE DIRECT IMPACT OF FINANCIAL REWARDS AND MEDIATION OF JOB SATISFACTION AND EFFECTIVE ORGANIZATIONAL COMMITMENT
Authors:   School of Economics and Business, Telkom University, Indonesia, Kristanti Farida Titik , Prasetio Arif Partono ,   School of Economics and Business, Telkom University, Indonesia, Indiyati Dian ,   School of Economics and Business, Telkom University, Indonesia, Madiawati Putu Nina ,   School of Communications and Business, Telkom University, Indonesia
Published: June 2021

Lecturer responsibilities in presenting learning materials and building students’ character is considered very important in preparing future workers/entrepreneur. However, those responsibilities still have not received proper attention in certain institutions and even from the government. If this goes on continuously, it is feared that they will lose wellperformed individuals. This study aimed to investigate the level of turnover intention from the lecturer in six private universities in Bandung. And the role of financial rewards, job satisfaction, and affective organizational commitment as antecedents. Data collected using an online questionnaire. The numbers of total lecturers in those universities were around 3000. This study used a non-probability sample and distributed 500 questionnaires through the human resources office. And after two months, there are 288 participants which willing to complete the questionnaire. After the more detailed screening, we have 121 responses that met our requirements and can be used in this study. The study found that financial rewards were significantly affected job satisfaction and affective organizational commitment. But it was not significantly affected turnover intention. Partially, job satisfaction and affective commitment have not mediated the relationship between financial rewards and turnover intention. But, simultaneously, both variables have significantly mediated the relationship. These results give new understanding to the managers in the educational organization regarding maintaining the turnover level of their lecturers. In the future, studies can be conducted to cover lecturers from other cities in Indonesia.
THE ROLE OF EMPLOYEE ENGAGEMENT ON JOB SATISFACTION AND ITS EFFECT ON ORGANIZATIONAL PERFORMANCE
Authors:   Graduate School, IPB University, Indonesia, Noercahyo Unggul Sentanu , Maarif Mohammad Syamsul ,   School of Business, IPB University, Indonesia, Sumertajaya I Made ,   Faculty of Math and Science, IPB University, Indonesia
Published: June 2021

The purpose of this research was to analyze the role of employee engagement from the perspective of job engagement and organization engagement on job satisfaction and its effect on organizational performance. This research was conducted at a multinational manufacturing chemicals company located in Tangerang and Cilegon. The population was approximately 121 employees consisting of three job levels: Manager, White Collar, and Blue Collar. A target sample determined approximately 93 employees. Sampling using a non-probability sampling approach with a quota sampling method. The questionnaire was distributed to the population, but only 86 respondents filled out and returned the questionnaire. Method of hypothesis testing using Partial Least Square of Structural Equation Modeling (PLS-SEM) approach. The results suggested that job engagement has a positive and significant effect on job satisfaction but does not significantly affect organizational performance. Next, organization engagement has a positive and significant effect on job satisfaction but does not significantly affect organizational performance. Furthermore, job satisfaction has a positive effect and significantly influences organizational performance. Future research is advisable to examine the relations of other variables such as workload, work-life balance, and implementation of an integrated management system, which, believed, can provide a comprehensive view of employee engagement, job satisfaction, and organizational performance.
THE EFFECT OF BRAND EXPERIENCE AND PERCEIVED VALUE ON BRAND LOYALTY MEDIATED BY BRAND TRUST
Authors:   Master of Management, Faculty of Economics and Business, Universitas Brawijaya, Indonesia, Pratiwi Rima Sera , Salim Ubud ,   Faculty of Economics and Business, Universitas Brawijaya, Indonesia, Sunaryo Sunaryo ,   Faculty of Economics and Business, Universitas Brawijaya, Indonesia
Published: June 2021

This study aimed to investigate the direct effect of brand experience and the perceived value of customers on brand loyalty and the indirect effect through brand trust as mediating variable. This study used a questionnaire distributed to 130 loyal customers of Susu Nandhi Murni produced by KUD Batu. The sampling technique was purposive sampling, and the method of data analysis was Partial Least Square (PLS). The results demonstrated a positive and significant direct effect of brand experience and perceived value on brand loyalty. In addition, brand experience and perceived value also had a positive and significant effect on brand trust and brand trust on brand loyalty. Furthermore, the indirect effect through brand trust as mediating variable also revealed a positive and significant effect, both on the brand experience and perceived value. Finally, future studies are suggested to investigate other variables that were not discussed in this research, such as brand image and brand satisfaction.
DOES ORGANIZATIONAL COMMITMENT MATTER? LINKING TRANSFORMATIONAL LEADERSHIP WITH ORGANIZATIONAL CITIZENSHIP BEHAVIOR (OCB)
Authors:   Faculty of Economics and Business, University of Muhammadiyah Malang, Indonesia, Novianti Khusnul Rofida
Published: June 2021

This research was conducted to identify the antecedents dimension of organizational commitment that consist of affective, continuance, and normative commitment to mediate transformational leadership on organizational citizenship behavior (OCB) in the salespeople’s banking sector in Malang, East Java. The population of this research was the employees in the banking sector that provides insurance and investment services in Malang city. The sampling technique used was non-probability sampling. A questionnaire was used as a research instrument. 118 responses were analyzed using Smart Partial Least Square software (Smart-PLS). The study result revealed that organizational commitment does not significantly affect OCB. The affective commitment was the best predictor in mediating the effect of transformational leadership on OCB. In contrast, continuance and normative commitment have an insignificant effect both directly and indirectly on OCB. This study was expected to be a reference for further research in the area of organizational outcome focused on organizational commitment and provide more information for decision making about the importance of leadership styles such as transformational leadership and organizational citizenship behavior.
ONLINE LEARNING MANAGEMENT USING GOOGLE SITES IN COVID-19 PANDEMIC ERA
Authors:   Universitas Wisnuwardhana Malang, Indonesia, Yuniarto Eko , Widayanti Febi Dwi ,   Universitas Wisnuwardhana Malang, Indonesia, Khasanah Robiul ,   Universitas Wisnuwardhana Malang, Indonesia
Published: June 2021

Covid-19 impacts the world of education, so learning is carried out online due to a policy of maintaining distance. One of the methods used to keep the learning going in the pandemic era is by utilizing e-learning. The use of applications in online learning is an innovation for teachers in preparing material to be used in the online learning management process. The purpose of this study aims to describe learning management using Google Sites in pandemic at SMP Muhammadiyah 4 Singosari. This research uses descriptive qualitative research methods. The data collection methods used in this study were interview, observation, and documentation during the learning process. The subject of this study were students of class VIII SMP Muhammadiyah 4 Singosari. Online learning management during pandemic conditions includes planning, organizing, implementing, and monitoring. Online learning will be carried out with the help of Google Sites as a medium for delivering material. The planning stage includes observation, preparation of lesson plans, collection of material sources, and preparation of learning media using Google Sites. The organizing stage includes determining the communication channels used for the online learning process and focusing resources on the target. The implementation stage is the interaction carried out by teachers and students during learning. The supervision stage includes the evaluation stage in learning. Learning evaluation is carried out through student attendance and student activeness in participating in learning. Student attendance recap shows an increase in each meeting. The use of Google Sites as a learning medium during the pandemic can be further developed to increase student motivation and make it easier for students to learn while carrying out online learning.
MARKET REACTIONS TO DOMESTIC MARKET OBLIGATION (DMO) COAL PRICE POLICY CHANGES: EVIDENCE FROM INDONESIA
Authors:   Universitas Negeri Malang, Indonesia, Safitri Titis Dyah , Maharani Satia Nur ,   Universitas Negeri Malang, Indonesia, Narullia Dwi ,   Universitas Negeri Malang, Indonesia
Published: June 2021

The announcement of the Domestic Market Obligation (DMO) coal price policy becomes the signal for investment decision making. The event was an announcement related to the government that can affect shares in the capital market. The form of capital market efficiency knows how equal the information that investors can absorb and the signal that indicates investors’ response, whether it is positive or negative. This research is a descriptive event study that uses twenty-one samples of coal mining subsector companies to determine capital market reactions to the Domestic Market Obligation (DMO) coal price policy announcement. During the observation period, there was a significant market reaction with a marked abnormal negative return. There is a leak of information before implementing policy, which makes the form of capital market efficiency is semi-strong form. Also, this is caused by the investor, which gets the difference of information degree based on the market efficiency hypothesis. The next research can use different event windows to increase the knowledge about the effect of the announcement of the Domestic Market Obligation (DMO) coal price policy towards market reaction.
EFFECT OF MANAGEMENT INNOVATION, TRANSFORMATIONAL LEADERSHIP, AND KNOWLEDGE SHARING ON MARKET PERFORMANCE OF INDONESIAN CONSUMER GOODS COMPANY
Authors:   Pelita Harapan University, Indonesia, Purwanto Agus , Purba John Tampil ,   Pelita Harapan University, Indonesia, Bernarto Innocentius ,   Pelita Harapan University, Indonesia, Sijabat Rosdiana ,   Pelita Harapan University, Indonesia
Published: June 2021

Transformational leadership greatly influences the management innovation and market performance of consumer good companies enterprises. According to the survey data about 244 employees of consumer goods companies, an empirical study was conducted on the relationship between transformational leadership, management innovation, knowledge sharing, market performance of consumer good companies enterprises, and analysis was made on the mediating effect of management innovation and knowledge sharing. The results showed that knowledge sharing has no significant effect on the market performance of consumer goods companies. Management innovation has not a significant effect on the market performance of consumer goods companies. Transformational leadership has no significant effect on the knowledge sharing of consumer goods companies. Transformational leadership has a significant effect on management innovation of consumer goods. Transformational leadership has no significant positive effect on the market performance of consumer goods companies.
Needs assessment for the development of an electronic cross-facility health record (ECHR) for pediatric palliative care: A design thinking approach (Preprint)
Authors: Busse Theresa Sophie , Jux Chantal , Kernebeck Sven , Dreier Larissa Alice , Meyer Dorothee , Zenz Daniel , Zernikow Boris , Ehlers Jan P.
Published: June 2021

BACKGROUND

Pediatric palliative care (PPC) is characterized by years of multisectoral and multiprofessional care. The exchange of information through effective communication between various PPC professionals is essential for high-quality care. Evidence shows that electronic cross-facility health records (ECHRs) provide useful support in this context. Given the specific needs of and content exchanged within PPC, the use of specific ECHRs in this area is necessary. To our knowledge, no ECHRs have been developed through a user-centered approach for this specific setting in Germany.

OBJECTIVE

The aim was to record PPC professionals’ needs (nurses, physicians, and secretaries) regarding ECHRs, as they may represent future users in inpatient and outpatient PPC as well as general practitioners and pediatrists from medical offices.

METHODS

Guided by design thinking, this study consisted of six steps: (1) empathize, (2) define, (3) ideate, (4) prototype, (5) test, and (6) iteration. First, qualitative interviews were conducted to assess the needs of PPC professionals. Second, the elicited needs were specified in focus groups (FGs). Prototypes of the ECHR (mock-ups) were then developed according to the needs mentioned in the interviews and were discussed in the FGs. Finally, the indicated needs were supplemented and specified in an iterative process. The mock-ups were further adapted according to these results.

RESULTS

Across seven main categories, medical history, actual medication, the emergency view with the most critical data, and messaging functions were identified as some participants’ desired core components of an ECHR. Utilizing design thinking facilitated an explicit articulation of user needs. The mock-ups clearly aligned the research and development team’s ideas with the simulated work in the ECHR for the users.

CONCLUSIONS

Developing an ECHR with the content that participants identified, which is currently being shared, that integrates overarching new views and functionality would make it possible to obtain real-time data during emergencies, to track what other PPC professionals have done, and to make the applied treatments visible to others. Moreover, it would give all providers with a more comprehensive picture of the complex conditions that are common in PPC. Concerning relevant content and functionality, user-centered design, and sensitivity to the various sectors regarding the needs of PPC professionals employed in those sectors emerged as strengths of the design thinking approach. An ECHR that directly addresses user needs will foster pediatric palliative care across sectors.
Impact of Jointly Using an e–Mental Health Resource (Self-Management And Recovery Technology) on Interactions Between Service Users Experiencing Severe Mental Illness and Community Mental Health Workers: Grounded Theory Study (Preprint)
Authors: Williams Anne , Fossey Ellie , Farhall John , Foley Fiona , Thomas Neil
Published: June 2021

BACKGROUND

e–Mental health resources are increasingly available for people who experience severe mental illness, including those who are users of community mental health services. However, the potential for service users (SUs) living with severe mental illness to use e–mental health resources together with their community mental health workers (MHWs) has received little attention.

OBJECTIVE

This study aims to identify how jointly using an interactive website called Self-Management And Recovery Technology (SMART) in a community mental health context influenced therapeutic processes and interactions between SUs and MHWs from their perspective.

METHODS

We conducted a qualitative study using a constructivist grounded theory methodology. Data were collected through individual semistructured interviews with 37 SUs and 15 MHWs who used the SMART website together for 2 to 6 months. Data analysis involved iterative phases of coding, constant comparison, memo writing, theoretical sampling, and consultation with stakeholders to support the study’s credibility.

RESULTS

A substantive grounded theory, discovering ways to keep life on track, was developed, which portrays a shared discovery process arising from the SU-worker-SMART website interactions. The discovery process included choosing to use the website, revealing SUs’ experiences, exploring these experiences, and gaining new perspectives on how SUs did and could keep their lives on track. SUs and MHWs perceived that their three-way interactions were enjoyable, beneficial, and recovery focused when using the website together. They experienced the shared discovery process as relationship building—their interactions when using the website together were more engaging and equal.

CONCLUSIONS

Jointly using an e–mental health resource elicited recovery-oriented interactions and processes between SUs and MHWs that strengthened their therapeutic relationship in real-world community mental health services. Further work to develop and integrate this novel use of e–mental health in community mental health practice is warranted.
Text Messaging Versus Email Messaging to Support Patients With Major Depressive Disorder: Protocol for a Randomized Hybrid Type II Effectiveness-Implementation Trial (Preprint)
Authors: Adu Medard Kofi , Shalaby Reham , Eboreime Ejemai , Sapara Adegboyega , Nkire Nnamdi , Chawla Rajan , Chima Chidi , Achor Michael , Osiogo Felix , Chue Pierre , Greenshaw Andrew J , Agyapong Vincent Israel
Published: June 2021

BACKGROUND

Major depressive disorder (MDD) accounts for 40.5% of disability-adjusted life years caused by mental and substance use disorders. Barriers such as stigma and financial and physical access to care have been reported, highlighting the need for innovative, accessible, and cost-effective psychological interventions. The effectiveness of supportive SMS text messaging in alleviating depression symptoms has been proven in clinical trials, but this approach can only help those with mobile phones.

OBJECTIVE

This paper presents the protocol for a study that will aim to evaluate the feasibility, comparative effectiveness, and user satisfaction of daily supportive email messaging as an effective strategy compared to daily supportive text messaging as part of the treatment of patients with MDD.

METHODS

This trial will be carried out using a hybrid type II implementation-effectiveness design. This design evaluates the effectiveness of an implementation strategy or intervention, while also evaluating the implementation context associated with the intervention. Patients with MDD receiving usual care will be randomized to receive either daily supportive email messaging or daily supportive text messaging of the same content for 6 months. The Patient Health Questionnaire-9, the Generalized Anxiety Disorder-7, and the 5-item World Health Organization Well-Being Index will be used to evaluate the effectiveness of both strategies. The implementation evaluation will be guided by the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework, as well as the Consolidated Framework for Implementation Research. All outcome measures will be analyzed using descriptive and inferential statistics. Qualitative data will be analyzed using thematic analysis.

RESULTS

Data collection for this trial began in April 2021. We expect the study results to be available within 18 months of study commencement. The results will shed light on the feasibility, acceptability, and effectiveness of using automated emails as a strategy for delivering supportive messages to patients with MDD in comparison to text messaging.

CONCLUSIONS

The outcome of this trial will have translational impact on routine patient care and access to mental health, as well as potentially support mental health policy decision-making for health care resource allocation.

CLINICALTRIAL

ClinicalTrials.gov NCT04638231; https://clinicaltrials.gov/ct2/show/NCT04638231

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/29495
Implementation of an Internet-Based Acceptance and Commitment Therapy for Promoting Mental Health Among Migrant Live-in Caregivers in Canada: Protocol (Preprint)
Authors: Fung Kenneth Po-Lun , Vahabi Mandana , Moosapoor Masoomeh , Akbarian Abdolreza , Jing-Wen Liu Jenny , Wong Josephine Pui-Hing
Published: June 2021

BACKGROUND

Psychological distress, isolation, feelings of powerlessness, and limited social support are realities faced by temporary migrant live-in caregivers in Canada. Furthermore, they experience multiple barriers in accessing mental health services due to their long work hours, limited knowledge of health resources, precarious employment, and immigration status.

OBJECTIVE

The Women Empowerment - Caregiver Acceptance & Resilience E-Learning (WE2CARE) project is a pilot intervention research project that aims to promote the mental well-being and resiliency of migrant live-in caregivers. The objectives include exploring the effectiveness of this program in achieving the following: (1) reducing psychological distress (depression, anxiety, and stress); (2) promoting committed actions of self-care; and (3) building mutual support social networks. Further, participants’ satisfaction with the intervention and their perceived barriers to and facilitators of practicing the self-care strategies embedded in WE2CARE will be examined.

METHODS

A total of 36 live-in caregivers residing in the Greater Toronto Area will be recruited and randomly assigned to either the intervention or waitlist control group. The intervention group will receive a 6-week web-based psychosocial intervention that will be based on Acceptance and Commitment Therapy (ACT). Standardized self-reported surveys will be administered online preintervention, postintervention, and at 6 weeks postintervention to assess mental distress (Depression, Anxiety and Stress Scale), psychological flexibility (Acceptance and Action Questionnaire), mindfulness (Cognitive and Affective Mindfulness Scale – Revised), and resilience (Multi-System Model of Resilience Inventory). In addition, two focus groups will be held with a subset of participants to explore their feedback on the utility of the WE2CARE program.

RESULTS

WE2CARE was funded in January 2019 for a year. The protocol was approved by the research ethics boards of Ryerson University (REB 2019-036) and the University of Toronto (RIS37623) in February and May 2019, respectively. Data collection started upon ethics approval and was completed by May 2020. A total of 29 caregivers completed the study and 20 participated in the focus groups. Data analyses are in progress and results will be published in 2021.

CONCLUSIONS

WE2CARE could be a promising approach to reducing stress, promoting resilience, and providing a virtual space for peer emotional support and collaborative learning among socially isolated and marginalized women. The results of this pilot study will inform the adaptation of an ACT-based psychological intervention for online delivery and determine its utility in promoting mental health among disadvantaged and vulnerable populations.

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/31211
Surgery With Arterial Resection for Hilar Cholangiocarcinoma: Protocol for a Systematic Review and Meta-analysis (Preprint)
Authors: Rebelo Artur , Ukkat Jörg , Klose Johannes , Ronellenfitsch Ulrich , Kleeff Jörg
Published: June 2021

BACKGROUND

In light of recent advances in multimodality treatment, an analysis of vascular resection outcomes in surgery for hilar cholangiocarcinoma is lacking.

OBJECTIVE

The aim of this meta-analysis is to summarize the currently available evidence on outcomes of patients undergoing arterial resection for the treatment of hilar cholangiocarcinoma.

METHODS

A systematic literature search in the databases PubMed/MEDLINE, Cochrane Library, and CINAHL, and the trial registries ClinicalTrials.gov and the World Health Organization International Clinical Trials Registry Platform will be carried out. Predefined outcomes are mortality (100-day and in-hospital), morbidity (Clavien-Dindo classification, any type of complication), vascular complications (thrombosis or stenosis of the portal vein or hepatic artery, pseudoaneurysms), liver failure, postoperative bleeding, duration of surgery, reoperation rate, length of hospital stay, survival time, actuarial survival (2-, 3-, and 5-year survival), complete/incomplete resection rates, histologic arterial invasion, and lymph node positivity (number of positive lymph nodes and lymph node ratio).

RESULTS

Database searches will commence in December 2020. The meta-analysis will be completed by December 2021.

CONCLUSIONS

Our findings will enable us to present the current evidence on the feasibility, safety, and oncological effectiveness of surgery for hilar cholangiocarcinoma with arterial resection. Our data will support health care professionals and patients in their clinical decision-making.

CLINICALTRIAL

PROSPERO 223396; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=223396

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/31212
KM-BERT: A Pre-trained BERT for Korean Medical Natural Language Processing (Preprint)
Authors: Kim Yoojoong , Lee Jeong Moon , Jang Moon Joung , Yum Yun Jin , Kim Jong-Ho , Kim Seongtae , Shin Unsub , Joo Hyung Joon , Song Sanghoun
Published: June 2021

BACKGROUND

With advances in deep learning and natural language processing, analyzing medical texts is becoming increasingly important. Nonetheless, a study on medical-specific language models has not yet been conducted given the importance of medical texts.

OBJECTIVE

Korean medical text is highly difficult to analyze because of the agglutinative characteristics of the language as well as the complex terminologies in the medical domain. To solve this problem, we collected a Korean medical corpus and used it to train language models.

METHODS

In this paper, we present a Korean medical language model based on deep learning natural language processing. The proposed model was trained using the pre-training framework of BERT for the medical context based on a state-of-the-art Korean language model.

RESULTS

After pre-training, the proposed method showed increased accuracies of 0.147 and 0.148 for the masked language model with next sentence prediction. In the intrinsic evaluation, the next sentence prediction accuracy improved by 0.258, which is a remarkable enhancement. In addition, the extrinsic evaluation of Korean medical semantic textual similarity data showed a 0.046 increase in the Pearson correlation.

CONCLUSIONS

The results demonstrated the superiority of the proposed model for Korean medical natural language processing. We expect that our proposed model can be extended for application to various languages and domains.
The effect of Health Literacy on COVID-19 Vaccine Hesitancy: The Moderating Role of Stress (Preprint)
Authors: Zhang Fan , Li Yue , Peng Sihui , Jiang Yue , Jin Huihui , Jin Huihui
Published: June 2021

BACKGROUND

The COVID-19 vaccine is an essential means to establish group immunity and prevent the spread of the pandemic. However, the public’s hesitation has created major difficulties to the promotion of the vaccine. By investigating the relationship between health literacy and COVID-19 vaccine hesitancy, as well as the potential moderating role of stress, the present study would provide critical insights for tailoring vaccine-promotion strategies.

OBJECTIVE

The two-fold research purpose is: i) address the effect of health literacy on people’s attitude toward COVID-19 vaccine, ii) clarify the role of stress in this effect.

METHODS

With structured questionnaires, an online survey was conducted to evaluate general public’s COVID-19 vaccine hesitancy, health literacy, and perceived stress. In total, 560 responses were collected, and moderated regression analysis was conducted to test the effect of health literacy on vaccine hesitancy among people with different levels of stress.

RESULTS

A total of 560 participants aged over 18 years were included in this study. About 39.8% of the respondents reported vaccine hesitancy, and this rate is higher among those aged 20-30 years old (83%) and female (71.3%). The results showed people with higher level of health literacy are less likely to have vaccine hesitancy (β = -2.00, 95%CI= [-3.00~ -0.99]). However, this effect was only among those with lower to moderate level of stress (β =-3.43, p<0.001), among the people with high stress, no significant effect of health literacy was found (β =-0.53, p>0.05).

CONCLUSIONS

By focusing on the effect of health literacy on COVID-19 vaccine hesitancy, the findings showed education program increasing individual’s health literacy may also effectively reduce the public’s vaccine hesitancy and promote accepting attitude. However, for people with high level of stress, other health programs need to be developed to enhance their positive attitude toward the COVID-19 vaccine. In conclusion, promotion strategies should be tailored for different populations, with considering individual factors such as health literacy and stress.
Doctors in Medical Data Sciences: A New Curriculum (Preprint)
Authors: Cussat-Blanc Sylvain , Castets-Renard Céline , Monsarrat Paul
Published: June 2021

UNSTRUCTURED

Machine Learning (ML), a branch of Artificial Intelligence, now competes with human experts in many specialized biomedical fields and will play an increasing role in precision medicine. As with any other technological advance in medicine, the keys to understanding must be integrated into practitioner training. To respond to this challenge, this viewpoint discusses some necessary changes in the health studies curriculum to help practitioners interpret decisions made by a machine and question them in relation to the patient's medical context. The complexity of technology and the inherent criticality of its use in medicine also necessitate a new medical profession. To achieve this objective, this viewpoint will propose new medical practitioners, with skills both in medicine and in data science, The Doctor in Medical Data Sciences.
Performance Analysis of OFDMA vs. NOMA in Cognitive Radio Network
Authors: Richard E. Alwin
Published: June 2021

Recent advancements in communication systems have resulted in a new class of multiple access schemes known as non-orthogonal multiple access (NOMA), the primary goal of which is to increase spectrum efficiency by overlapping data from different users in a single time-frequency resource used by the physical layer. NOMA receivers can resolve interference between data symbols from various users, hence increasing throughput. Initially, the combination of SCMA and orthogonal frequency division multiplexing (OFDM) is addressed, establishing a baseline for the overall SER performance of the multiple access strategy. Furthermore, this work suggests the merging of SCMA with generalised frequency division multiplexing (GFDM).GFDM is an intriguing possibility for future wireless communication systems since it is a very flexible non-orthogonal waveform that can imitate various different waveforms as corner cases. This research suggests two methods for integrating SCMA with GFDM.
Effectiveness of ADAS in Existing Vehicles
Authors: Agarkar Arpit S
Published: June 2021

Around the whole world, lot of accidents occur due to inattentive driving and human errors. Partial Autonomous Driver Assistance System can be of lot of help to the driver in avoiding the collision and maintain the control of the vehicle by giving different warning signals. The system consists of (i) Forward Collision Warning (ii) Lane Departure Warning. In the existing vehicles, by adding RADAR Sensors and Camera and a microcontroller for processing, it can be used to track the lanes and gives an acoustic warning in advance if there is lane departure or any vehicle or pedestrian ahead. The proposed system can be implemented on raspberry pi microcontroller board.
Mindset predicts consumer variety seeking through learning goal orientation: The role of susceptibility to interpersonal influence
Authors: Li Jiqiang , Sun Lining
Published: June 2021

We examined how people's belief that human traits are either malleable or fixed—that is, mindset—can shape consumers' variety seeking through learning goal orientation. We also tested the moderating effect of susceptibility to interpersonal influence in the mindset–variety
seeking relationship. Participants were 364 adults in the US, who completed a survey on mindset, variety seeking, learning goals, and susceptibility to interpersonal influence. Results show that consumers with a growth (vs. fixed) mindset were more likely to engage in variety seeking as they
were more motivated by learning goals. This relationship was more evident when they cared less (vs. more) about others' approval. These findings offer new evidence for how mindset is related to consumption tendencies, provide insight into the conditions under which these relationships are
stronger or weaker, and suggest that practitioners should pay more attention to mindset when they are developing marketing strategies.
Psychological empowerment and work burnout among rural teachers: Professional identity as a mediator
Authors: Ding Jinliang , Xie Zechen
Published: June 2021

We examined the relationship between psychological empowerment and work burnout as mediated by professional identity. Participants were 650 primary and secondary school teachers from nine rural provinces in China. The results indicate that both psychological empowerment and professional
identity were significantly and negatively related to work burnout, and that psychological empowerment was significantly and positively associated with professional identity. Furthermore, professional identity partially mediated the relationship between psychological empowerment and work burnout.
These findings advance research on the psychology of professional identity by clarifying the relationship between psychological empowerment and work burnout.
Cartographic research method of developing recommendations on prevention of water-related emergencies
Authors: Kurepina N.Yu. , Rybkina I.D.
Published: June 2021

In the paper, the use of cartographic research method for the analysis and generalization of materials describing extreme events associated with rarely recurring high water and flooding in river basins of the Upper Ob is proposed. Basing on statistical data obtained from municipalities of the adjacent regions (Altai Krai, Republic of Altai, Kemerovo, Novosibirsk and Tomsk oblasts), including the information provided by territorial bodies of the RF Emergency Situations Ministry, we created a database for assessing actual and probable damage to population and economy of the study territories. Actual damage is generalized and analyzed in the context of river basins and municipalities of the entities, i.e. subjects of the Russian Federation. In order to assess probable damage, cartographic sources, including open data from the Internet as well as modern software tools were involved. The estimation of probable damage to population and economic objects was performed by the example of settlements (including those suffered from extreme flooding of 2014) located in the Charysh basin (Altai Krai). For that GIS projects and a series of damage evaluation maps were created. River basins of the Upper Ob regions were ranked according to recurrence frequency of extreme events and the extent of actual damage to population and economy there in 2004–2018. On the basis of these results, recommendations to prevent emergencies caused by the negative impact of water were developed.
The Transatlantic Narco-Nexus: South America, Africa, and Europe in the contemporary drug-trafficking dynamics
Authors: Rodrigues Thiago , Viviana Porto Carol , de Freixo Adriano
Published: June 2021

The article analyzes the contemporary transatlantic flow of illegal drugs, taking on account the current transformation of the connections among South American, African and European Drug-Trafficking Organizations (ODTs) and the tendency to securitize this traffic which interests the Brazilian public, national and regional security and diplomatic policies. The article presents a history of the transatlantic drug- trafficking and the its contemporary contours in order to suggest viable initiatives to cope with this new and aggravated panorama pushed through by the so-called “war on drugs”.
Dynamic View of Pandemic Circumstances with Government Interventions and Socioeconomic Factors
Authors: Wang Wenru , Vasarhelyi Miklos A. , de Freitas Marcelo Machado , da Rosa Fabricia Silva
Published: June 2021

The Novel Coronavirus Disease, COVID-19, was declared a worldwide pandemic by the World Health Organization (WHO) on March 11, 2020 (WHO 2020). Scientists in different fields have contributed to study the pandemic development and to provide support to government policies. However, the traditional measures of individual health, population health, and policy effects have received the criticism that many of them reflected the pandemic inaccurately and belatedly. This study evaluates the pandemic circumstances from the auditor's perspective, applies the system dynamics theory, and proposes dynamic models to understand the ongoing pandemic using business measurements and analytical technologies. This study also works on estimations of the feedback effects of pandemic-related policy measures. The deliverables of this study establish a dynamic view to understand the current pandemic and provide the government with a simulation tool to visualize the impacts of government interventions at different levels.
Embracing Emerging Technologies and Artificial Intelligence into the Undergraduate Accounting Curriculum: Reflections from the UAE
Authors: Qasim Amer , El Refae Ghaleb A. , Eletter Shorouq
Published: June 2021

This study explores the implications of market digital transformation in the United Arab Emirates (UAE) for the undergraduate accounting curriculum. Responding to a number of government initiatives toward artificial intelligence (AI) transformation, corporations and government agencies in the UAE have recently started to test and adopt AI, Blockchain Technology (BT), and Data Analytics (DA) in their operations. This digital transformation in the business environment raises concerns as to whether existing accounting curricula are preparing accounting graduates for the emerging IT needs relevant to the existing accounting job market. To this end, this study explores the extent to which the current accounting curriculum in the UAE reflects the current digital transformation in the country.
Association Between Glucagon-Like Peptide 1 Receptor Agonist and Sodium–Glucose Cotransporter 2 Inhibitor Use and COVID-19 Outcomes
Authors: Kahkoska Anna R. , Abrahamsen Trine Julie , Alexander G. Caleb , Bennett Tellen D. , Chute Christopher G. , Haendel Melissa A. , Klein Klara R. , Mehta Hemalkumar , Miller Joshua D. , Moffitt Richard A. , Stürmer Til , Kvist Kajsa , Buse John B. ,   N3C Consortium, Duong Tim Q.
Published: June 2021

OBJECTIVE

To determine the respective associations of premorbid glucagon-like peptide-1 receptor agonist (GLP1-RA) and sodium–glucose cotransporter 2 inhibitor (SGLT2i) use, compared with premorbid dipeptidyl peptidase 4 inhibitor (DPP4i) use, with severity of outcomes in the setting of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

RESEARCH DESIGN AND METHODS

We analyzed observational data from SARS-CoV-2–positive adults in the National COVID Cohort Collaborative (N3C), a multicenter, longitudinal U.S. cohort (January 2018–February 2021), with a prescription for GLP1-RA, SGLT2i, or DPP4i within 24 months of positive SARS-CoV-2 PCR test. The primary outcome was 60-day mortality, measured from positive SARS-CoV-2 test date. Secondary outcomes were total mortality during the observation period and emergency room visits, hospitalization, and mechanical ventilation within 14 days. Associations were quantified with odds ratios (ORs) estimated with targeted maximum likelihood estimation using a super learner approach, accounting for baseline characteristics.

RESULTS

The study included 12,446 individuals (53.4% female, 62.5% White, mean ± SD age 58.6 ± 13.1 years). The 60-day mortality was 3.11% (387 of 12,446), with 2.06% (138 of 6,692) for GLP1-RA use, 2.32% (85 of 3,665) for SGLT2i use, and 5.67% (199 of 3,511) for DPP4i use. Both GLP1-RA and SGLT2i use were associated with lower 60-day mortality compared with DPP4i use (OR 0.54 [95% CI 0.37–0.80] and 0.66 [0.50–0.86], respectively). Use of both medications was also associated with decreased total mortality, emergency room visits, and hospitalizations.

CONCLUSIONS

Among SARS-CoV-2–positive adults, premorbid GLP1-RA and SGLT2i use, compared with DPP4i use, was associated with lower odds of mortality and other adverse outcomes, although DPP4i users were older and generally sicker.
Single-Cell Mapping of GLP-1 and GIP Receptor Expression in the Dorsal Vagal Complex
Authors: Ludwig Mette Q. , Todorov Petar V. , Egerod Kristoffer L. , Olson David P. , Pers Tune H.
Published: June 2021

The dorsal vagal complex
(DVC) in the hindbrain, composed of the area postrema, nucleus of the solitary
tract and dorsal motor nucleus of the vagus, plays a critical role in
modulating satiety. The incretins glucagon-like peptide-1 (GLP-1) and
glucose-dependent insulinotropic polypeptide (GIP) act directly in the brain to
modulate feeding, and receptors for both are expressed in the DVC. Given the
impressive clinical responses to pharmacologic manipulation of incretin
signaling, understanding the central mechanisms by which incretins alter
metabolism and energy balance are of critical importance. Here, we review
recent single-cell approaches used to detect molecular signatures of GLP-1 and
GIP receptor-expressing cells in the DVC. In addition, we discuss how current
advancements in single-cell transcriptomics, epigenetics, spatial
transcriptomics, and circuit mapping techniques have the potential to further
characterize incretin circuits in the hindbrain.
Psychometric Assessment of Young Visitors at the National Museum Of Malaysia
Authors: Mahphoth Mohd Halim , Sulaiman Zuraidah , Loon Koe Wei , Kamarudin Nur Asyikeen , Dirgantari Puspo Dewi
Published: June 2021

Abstract: Museums have become an important institution for learning activities especially for young visitors as it provides significant function towards educational benefits and knowledge enrichment. The actual outcomes from learning experience need to be encountered in order to indicate satisfying experience level from museum visiting. However, the assessment of satisfying experience on museum visit is entirely lacking in the existing literatures. Therefore, this study proposes a set of assessment for young visitors in order to evaluate their satisfying experiences in museum. The items were adapted and developed from the concept of satisfying experiences established by museum practitioners. This paper aims to present evidence in order to show the validity of the survey data and the instrument meets the requirements of specific measurements as determined by Rasch model. It is hoped that the assessment of satisfying experience will benefit researchers as well as practitioners and educators in managing the quality of young visitors experience in museum. The literature also intends to add to the body of knowledge in museum context.

 

Keywords: Learning, Museum, Rasch model, Satisfying experiences, Young visitors