bluuebunny/crossref_metadata_2025 huggingface dataset:
Oil spills forecasting in rail accidents
Authors: Elizariev Alex , Yusupov Timur , Elizarieva Elena
Published: June 2019

Objective: To scientifically substantiate and develop forecasting basis of emergency situations consequences on railway transport. Methods: Theoretical generalization and analysis of the current knowledge and understanding of oil spills forecasting, a geographic information system. Results: In accordance with the analysis of statistical data, the emergency situation during the transportation of oil and oil products by rail are associated more with mechanical damage to special tanks and release of petroleum products into the environment with subsequent ignition, or by contamination of land or water areas. One of the key safety components on rail transport of petroleum products is the prediction of possible emergency situations, modelling of development processes of the strait of petroleum products and risk assessment. Based on the analysis of existing methods of calculation of the consequences strait of petroleum products, as well as features of the simulation of the expiry with use of modern software such as Autodesk Inventor, ArcGIS, Surfer, the proposed methodological framework for prediction of consequences of emergency situations on objects of railway transport. The paper shows the opportunity on the basis of threedimensional models of the terrain in the zone of emergency, by means of geographic information modeling to determine the shape of the spill of petroleum product of a multifactorial consideration of the different parameters determining the quantitative and qualitative sides of the processes of the strait of oil products will allow to improve the accuracy of predictive assessments, and the use of modern IT-technologies to provide efficiency calculations. Practical importance: Applicationof the proposed approach will determine the quality of any system of support of decision-making, especially when planning rescue operations, including in the justification of the choice of those or other technologies of their conducting and use of various rescue equipment.
Evaluation of sorbents’ oil capacity properties at various temperatures
Authors: Nurutdinov Azamat , Yamaletdinova Klara
Published: June 2019

Objective: The oil capacity properties of the sorbents used for oil collection are qualitatively estimated at various temperatures. One of the factors securing sustained rail transport development is taking measures to prevent and eliminate the accidental spillages of dangerous goods including oil and oil products. Such accidents occur causing significant environmental contamination. Methods: Using sorbents for containment and elimination of such accidents has a good track record. Their properties have not been, however, sufficiently investigated at various temperatures. The sorbents’ oil capacity is determined by the standard gravimetric method using the difference between the weight of a sorbent impregnated with oil product and that of a pure sorbent based on 1 g (kg) of a pure sorbent. Results: Oil viscosity grows as the temperature goes down. The research findings show higher sorbents’ oil capacity figures caused by a changed oil recovery mechanism due to its higher viscosity: at a low or moderate viscosity, oil sorbs inside the sorbent volume, whereas at a high viscosity (above 200 mm2/s) sorbent surface adhesion occurs. Practical importance: A qualitative analysis of sorbents is important for ensuring environmental safety.
Industrial waste resource potential of ore mining and processing enterprises of the Southern Urals.
Authors: Gylmutdynova Rimma , Michurin Sergey , Yelyzaryeva Elena
Published: June 2019

Objective: To assess the industrial waste resource potential in the districts of ore mining and processing enterprises (GOK) of the Southern Urals. Methods: Chemical analysis of samples of water and soil was conducted. Results: The samples of slag were collected and analyzed near an old copper plant in Sibay, the samples taken from stock piles and tailing dumps of Uchalynskiy, Gaiskiy and Burybayevskiy ore mining and processing enterprises. It was established that mineral separation plants’ waste contain 0,3-0,4% of zinc, 0,2-0,3% of copper, 20-35% of sulfur, and more than 35% of iron. The analysis of water samples taken from an old open pit and soil collected in the district of copper pyrite deposit Kul Yurt Tau indicated high content of S, Fe, Co, Cu, Zn, Pb etc. in total dry solids of water samples after after boiling down, high concentration of the above mentioned elements were detected, the latter indicated severe contamination of soil and water in the deposit’s area. Practical importance: The recycling of old GOK waste might be the solution to the existing problem, taking into account the fact, that at present deep-seated deposits of copper and zinc are exploited with a high level of economic costs. The tailing dumps of the Urals’ enterprises considerably excel many other deposits in total reserves. With technological development of beneficiation, waste may undergo recycling with the extraction of useful mining elements, while the remaining rock may be applied in the production of construction materials or returned to the places of ore mining. Moreover, the utilization of raw materials’ extraction and processing waste (on an industrial scale) will provide ecological rehabilitation of territories exposed to negative impact of facilities used for economic activities.
Telecommunication systems and high-speed railway transport networks
Authors: Kanayev Andrey , Pryvalov Andrey , Kotov Vladimir , Lebedinskiy Arkadiy , Plekhanov Pavel , Poyenkov Dmytriy
Published: June 2019

Objective: To consider the main approaches to organization of systems and communication networks on high-speed railway transport and provide cyber security on the basis of current international and home practice in the given sphere. Methods: Game-theory approach, hierarchy analysis method as well as topological transformation of stochastic networks were applied in the given study. Results: It was detected that a single realization of organizational and technical measures on cyber security cannot provide strong security from threats of cyber security during a long period of time; the latter is connected with constant development of data infrastructure, modification of methods, as well as the methods of attacks, potential attacker opportunities and other factors. Telecommunication networks’ security (TKS) of OJSC “Russian railways” and high-speed railway lines (VSM) from cyber impact is a systemic problem, for the solution of which fundamental research studies are to be conducted, aimed at the detection of basic patterns of information confrontation and directions of TKS cyber security provision and, subsequently, research and development activities for creating an automated communication control system of OJSC “Russian railways” and VSM, the constituent part of which is a subsystem of TKS information security. It is advisable to create an expert council based at regional transport universities, which provide extensive analysis conduct of systems and means of providing information security offered by the industry, as well as cyber security of OJSC “Russian railways” and VSM critically important systems including TKS. Practical importance: The realization of the suggested approach to OJSC “Russian railways” and VSM cyber security provision will make it possible to form the conditions for safe functioning of elements of information infrastructure, provide the creation, effective functioning and the improvement of cyber security control system, as well as to minimize damage from possible attack attempts.
On interaction of a rolling stock and geometrical parametres of high-speed networks’ route
Authors: Shkurnikov Sergey , Morozova Olga
Published: June 2019

Objective: Due to the lack of global experience of holding on one track high-speed passenger trains (moving at a speed up to 400 km/h), high-speed passenger trains (moving at a speed up to 250 km/h) and special freight trains (accelerating to a speed of more than 200 km/h), the only possible way of studying the influence of a train on a track is computer simulation modeling. The analysis of the existing computer programs was carried out and the most effective programme for the solution of combined train movement was selected. Methods: Simulation modeling was applied. On the basis of the obtained model the possibility of “Universal mechanism” software practical application was considered. Results: A test simulation model of a high-speed train carriage was developed in “Universal mechanism” software application. Preliminary results showed the possibility of its usage for the study of a high-speed train and track interaction. Practical importance: Modern computer technologies make it possible to solve the tasks of dynamic interaction with a high degree of accuracy. Among the variety of software used for the study of dynamic behavior of a railway vehicle in Russia, “Universal mechanism” software application is of wide popularity and may be used for the study of dynamic behavior of different types of trains on railway tracks of different plans and profiles.
PARALLEL OPERATION OF HYDROGEN POWER SOURCE WITH CURRENT INVERTER AND SYNCHRONOUS GENERATOR IN SELF-CONTAINED ELECTRIC-POWER SYSTEMS OF ALTRENATING CURRENT
Authors: Burkov Anatoliy , Marykyn Alexander , Nikityn Victor , Tretyakov Alexander
Published: June 2019

Objective: The data on the synthesis of a combined electric power source for a self-contained electric-power system with a diesel generator (turbo-generator) and hydrogen power source was presented in the article. Objective: To justify the structure and parameters of a power channel of a self-contained electric power plant based on power augmentation with parallel operation on the total load of two electric power sources – synchronous generator and hydrogen power source. Methods: Mathematical modeling of the main power processes was applied, including the processes of active and reactive power distribution control in a self-contained electric power system with parallel operation of synchronous generator and hydrogen power source. Results: The tasks of structural synthesis of a combined power plant with current-based electronic inverter application, as well as justifications of power-efficient operation criteria and control algorithms of a self-contained electric power system with minimized power interchange between synchronous generator and current inverter were set and solved. Practical importance: New results are recommended to use in the design of power systems with improved technical and economic as well
RAIL TRAFFIC SAFETY CONTROL IN REGIONS WITH NATURAL HAZARDS
Authors: Elizariev Alexey , Titova Tamila , Elizarieva Elena , Akhtyamov Rasul , Gaponov Vitaliy
Published: June 2019

Objective: To conduct safety evaluation of urban land in the process of goods traffic by railway transport in regions with natural hazards on the basis of system approaches. Methods: During safety evaluation, modern urban areas were considered as a complex multilevel system, concentrated mainly in large water basins and characterized by the presence of the developed railway infrastructure. Results: A complex approach of determining natural and anthropogenic hazards interrelation within the limits of an urban land was introduced. By breaking the problem of natural and anthropogenic causes of contingency within the limits of an urban land, the processes and phenomena of interrelation were considered, which, in case of integrated accounting, provides an opportunity to improve the level of forecast of land resistance to hazard occurrence. Practical importance: The developed approach and calculation data make it possible on a reasonable basis, to select measures to increase resistance, to assess the necessity in efficiency improvement of hazardous processes and phenomena monitoring, as well as to restrict the use of transportation infrastructure elements.
MODERN ARRANGEMENT OF PARKING SPACE ON TRANSFER HUBS FROM THE VIEWPOINT OF UTILIZATION EFFICIENCY OF URBAN AREAS
Authors: Andreeva Ludmila , Muzykin Ivan
Published: June 2019

Objective: To analyze the efficiency of building multilevel automated garages on transfer nodes, to reveal problems, connected with normative-technical control of automated parking design. Methods: The comparison of fixed and variable costs on construction and maintenance of different types of multilevel parking – automated and ramp, built-in and detached, underground and located at ground level, consideration of foreign and long-term domestic experience of multilevel parking lots in transfer hubs. Results: The value of transfer hubs in the system of urban and passenger transport was discovered as well as, classification of transfer hubs was specified, from the viewpoint of urban planning, the emphasis was made on the significance of proper arrangement on the territory of transfer hubs, taking into account space economy principle and whether the transfer hub harmoniously fits into urban environment, the spheres of application of different types of car-parks were specified, the advantages of automated car-parks over the conventional flat and multilevel ramp car-parks were revealed, the analysis of costs on construction and maintenance of different multilevel car-parks was carried out, the conclusions were made on the use of automated car-parks in the conditions of transfer hubs, functional area of automated car-parks in transfer hubs was presented as well as the documents, reflecting the normativetechnical control of automated parking design, recommendations were given on implementation of automated parking construction technology in Russia. Practical importance: The obtained conclusions may be applied in the design of transfer hubs in the cities of Russia, especially in restrained urban conditions. The given normative-technical control documents will make it possible to improve automobile parking convenience. Propagation of mechanization and application of intelligence systems in parking facilities will provide considerable economic benefit.
Charlie van der Horst (1952-2019)
Authors: Lederman Michael M.
Published: June 2019

Charlie van der Horst, an emeritus professor at the University of North Carolina and a friend of Pathogens and Immunity, disappeared from sight on Friday, June 14 during a marathon swim in the Hudson River. His death was confirmed. Few who knew him would call him Charles as formality was not his strong-suit. Charlie was born in Holland to a Dutch father and a Polish Holocaust survivor mother. His family moved to the Buffalo, New York area and sent Charlie to school at Andover. He attended Duke University where he captained the varsity swim team in 1973-74. He remained a powerful swimmer, competing often in national Masters’ competitions. He received his MD degree from Harvard in 1979 and trained in medicine at Montefiore Medical Center and Infectious Diseases at the University of North Carolina. He was an expert in the management of fungal diseases and when the AIDS epidemic began, he knew he had to commit his career to AIDS research and care. He led a highly successful AIDS Clinical Trials Unit at the University of North Carolina and was a respected leader in this national consortium who gained international recognition and respect for his work. More than most anyone else I know, Charlie was driven to fight for justice, anywhere, any time. At the 2000 IAS meeting in Durban, South Africa he recognized that the greater AIDS need was in the developing world and he redirected his entire career towards the development of research and care programs in Africa. When Ebola hit West Africa, Charlie rushed to Liberia to help. In the U.S., Charlie was on the front lines urging his state legislature to deal fairly with all North Carolinians, working hard to fight for equity in health care. He was beloved by so many, respected for his talents, admired for his decency. He was, as my grandmother would have said—a mentsch—and more. Our world is lucky to have had him and is diminished by his loss.
PENGARUH PENGGUNAAN LKS BERBASIS INKUIRI TERBIMBING MATERI ELASTISITAS DAN HUKUM HOOKE TERHADAP HASIL BELAJAR SISWA
Authors: Nurcahyati Kartika , Distrik I Wayan , Wahyudi Ismu
Published: June 2019

Tujuan penelitian ini adalah untuk mengetahui adanya pengaruh LKS berbasis inkuiri terbimbing materi elastisitas dan hukum Hooke terhadap hasil belajar siswa. Penelitian ini menggunakan desain quasy experimental dengan teknik pengambilan data purposive samping. Penelitian dilakukan di SMA Negeri 2 Mesuji semester genap tahun ajaran 2016/2017 pada kelas IPA 1 sebagai kelas eksperimen dan kelas IPA 2 sebagai kelas kontrol. Data dianalisis melalui uji independent sample t-test. Hasil penelitian menunjukkan bahwa terdapat pengaruh penggunaan LKS berbasis inkuiri terbimbing materi elastisitas dan hukum Hooke terhadap hasil belajar siswa secara signifikan yang ditunjukkan nilai sign. ≤ 0,05.
PENGEMBANGAN LKM BERBASIS MC-GP MENGGUNAKAN CAT UNTUK MELATIH KEMAMPUAN BERPIKIR KRITIS MAHASISWA
Authors: Wicaksono Indro , Sutarto Sutarto , Marzuki Imam
Published: June 2019

Tujuan penelitian ini adalah menghasilkan perangkat pembelajaran berupa Lembar Kegiatan Mahasiswa (LKM) berbasis Media Cetak Gambar Proses (MC-GP) menggunakan Computer And Thecnology (CAT) pada matakuliah Fisika Dasar materi kinematika gerak lurus yang layak digunakan untuk melatihkan kemampuan berpikir kritis mahasiswa. Subjek penelitian ini yaitu mahasiswa semester 1 prodi Teknik Industri dan Teknik Elektro Universitas Panca Marga (UPM) Tahun Ajaran 2018/2019. Kemampuan berpikir kritis yang diukur menyesuaikan dengan indikator berpikir kritis yang disingkat dengan FRISCO. Model pengembangan yang digunakan merujuk pada model pengembangan 4-D dengan tahapan Definition, Design, Development, dan Dissemination. Desain penelitian yang digunakan yaitu One group pretest-postest design. Teknik pengumpulan data penelitian menggunakan instrumen penelitian yang meliputi instrumen validasi LKM dari ahli media, instrumen tes kemampuan berpikir kritis (TKBK) berupa tes, dan instrumen respon mahasiswa berupa angket. Hasil penelitian yang dihasilkan menunjukkan bahwa hasil validasi LKM MC-GP dan TKBK berkategori valid. Hasil TKBK mahasiswa mengalami peningkatan dengan skor rata-rata peningkatannya 0,73 (gain tinggi). Respon mahasiswa terhadap penggunakan LKM MC-GP berkategori sangat kuat.
PEMBELAJARAN FISIKA BERBASIS MASALAH MELALUI METODE EKSPERIMEN DAN DEMONSTRASI DITINJAU DARI KEMAMPUAN MENGGUNAKAN ALAT UKUR DAN SIKAP ILMIAH SISWA
Authors: Al IIdrus Kadir
Published: June 2019

Tujuan penelitian ini adalah untuk mengetahui: (1) pengaruh penggunaan metode pembelajaran eksperimen dan demonstrasi terhadap prestasi belajar, (2) pengaruh kemampuan menggunakan alat ukur terhadap prestasi belajar, (3) pengaruh sikap ilmiah terhadap prestasi belajar, (4) interaksi antara metode pembelajaran dengan kemampuan menggunakan alat ukur terhadap prestasi belajar, (5) interaksi antara metode pembelajaran dengan sikap ilmiah terhadap prestasi belajar, (6) interaksi antara kemampuan menggunakan alat ukur dengan sikap ilmiah terhadap prestasi belajar, (7) interaksi antara metode pembelajaran dengan kemampuan menggunakan alat ukur dan sikap ilmiah terhadap prestasi belajar.

Penelitian ini menggunakan metode eksperimental (experimental research). Populasi penelitian adalah seluruh siswa kelas XI program IPA SMA Negeri 2 Mataram tahun pelajaran 2017/2018, sebanyak 8 kelas. Sampel penelitian ditentukan secara acak dengan teknik cluster random sampling sebanyak dua kelas. Kelas eksperimen 1 dengan metode eksperimen dan kelas eksperimen 2 dengan metode demonstrasi. Teknik pengumpulan data menggunakan metode tes untuk mendapatkan data prestasi belajar kognitif dan kemampuan menggunakan alat ukur, sedangkan metode angket untuk mendapatkan informasi sikap ilmiah dan prestasi belajar afektif. Uji hipotesis penelitian menggunakan anava tiga jalan dengan desain faktorial 2x2x2 dan frekuensi sel tidak sama.

Dari hasil penelitian dapat disimpulkan bahwa: (1) Tidak ada pengaruh penggunaan metode pembelajaran eksperimen dan demonstrasi terhadap prestasi kognitif (p-value = 0,151) dan afektif (p-value = 0,368). (2) Tidak ada pengaruh kemampuan menggunakan alat ukur terhadap prestasi kognitif (p-value = 0,593) dan afektif (p-value = 726). (3) Tidak ada pengaruh sikap ilmiah terhadap prestasi kognitif (p-value = 0,399) dan afektif (p-value = 0,084). (4) Tidak ada interaksi antara metode pembelajaran dengan kemampuan menggunakan alat ukur terhadap prestasi kognitif (p-value = 0,832). (5) Tidak ada interaksi antara metode pembelajaran dengan sikap ilmiah terhadap prestasi kognitif (p-value = 0,839). (6) Tidak ada interaksi antara kemampuan menggunakan alat ukur dengan sikap ilmiah terhadap prestasi kognitif (p-value = 318). (7) Ada interaksi antara metode pembelajaran dengan kemampuan menggunakan alat ukur dan sikap ilmiah terhadap prestasi kognitif (p-value = 0,029).
Pulse Wave Harmony: Ancient Wisdoms for Modern Age
Authors: Celka Patrick , Samten Lobsang , Brucet Marina , Alabdulgader Abdullah
Published: June 2019

Background: This research presents the use of photoplethsmography combined with Traditional Tibetan Pulse reading for the estimation of the three energies of a person: Activity, Transformation and Stability. The three energies derive from the four elements which are known from antiquity, both East and West, which considered life and the cosmos as an inseparable whole. Therefore the three energies composing the human functions are a reflection of our life as well as the cosmos. Method: Our work is presented in two studies. The first study presents the development of the technique of photoplethsmography to classify the three energies. The second study presents a validation of this methodology on mental stress and relaxation. Results: Energies classification achieved a sensitivity above 85% and specificity above 86%. Mental stress and relaxation could be significantly discriminated from baseline condition. Harmonic analysis gave further insights into the dynamic of the pulse wave under stress/relaxation. Conclusion: The photoplethsmogram contains information pertaining to the mental and physiological state of a person as interpreted with the Eastern energies concepts. The implication of this work points towards a holistic understanding and impact of human activities, health and its environment.
Effect of Different Salinities Gradient on Fatty Acid Composition, Growth, Survival and Reproductive Performance of Moina macrocopa (Straus 1820) (Crustacea, Cladocera)
Authors: Wan Rasdi Nadiah , Suhaimi Hidayu , Hagiwara Atsushi , Ikhwanuddin Mhd. , Ghaffar Mazlan A. , Yuslan Amirah , Najuwa Syarifah
Published: June 2019

Salinity is a known factor which shapes population dynamics and community structure through direct and indirect effects towards aquatic ecosystems. The responses of Moina macrocopa (Cladocera) collected from Setiu Wetland lagoon (Terengganu) were evaluated through manipulative laboratory experiments to understand the ability of M. macrocopa to tolerate under high salinity stress. Specifically, the fatty acid composition, growth, survival and reproduction of this cladocerans species were examined. Sodium chloride (NaCl) were used in the treatments water with the concentration 0, 4, 6, 8, 12, and 15psu. Fatty acid levels were determined using Gas Chromatography and Mass Spectrophotometry (GC-MS). Results clearly indicate that normal conditions give the highest content of fatty acid, especially the polyunsaturated fatty acid content like EPA (eicosapentaenoic acid), ALA (alpha-linoleic acid), ARA (arachidonic acid) and DHA (docosahexaenoic acid). Furthermore, M. macrocopa survival also was best at 0psu, with percentage reached 98%, whereas the opposite occurred at 15psu, with approximately 9% of viable animals survived. On other aspects, M. macrocopa also showed the highest reproduction rate at 0psu (e.g. average initial age of reproduction, 4.33±0.58 days) compared with other salinities level. Interestingly, the difference in terms of growth at different salinities was unapparent, an unexpected outcome when adverse effects such as osmoregulation pressure on the organism are considered. Based on the results, we conclude that M. macrocopa can only tolerate salinity below 8psu and, is unable to withstand stressful environmental condition engendered with salinities above 8psu.
Dietary Fiber and Gut Microbiota in Renal Diets
Authors: Camerotto Carla , Cupisti Adamasco , D'Alessandro Claudia , Muzio Fulvio , Gallieni Maurizio
Published: June 2019

Nutrition is crucial for the management of patients affected by chronic kidney disease to slow down disease progression and to correct symptoms. The mainstay of nutritional approach to renal patients is protein restriction coupled with adequate energy supply to prevent malnutrition. However, other aspects of renal diets, including fiber content, can be beneficial. This paper summarizes the latest literature on the relationship between the type of dietary fiber and prevention and management of CKD, with special attention to intestinal microbiota and the potential protective role of renal diets. A proper amount of fiber should be recommended not only in general population but also in chronic kidney disease patients, to asses an adequate composition and metabolism of intestinal microbiota and to reduce the risks connected with obesity, diabetes and dyslipidemia.
Key Parameters in the Manufacture of SiC-Based Composite Materials by Reactive Melt Infiltration
Authors: Caccia Mario , Narciso Javier
Published: June 2019

The manufacture of SiC-based composites is quite widespread, and currently different methods are employed for to produce them. The most efficient method, taking into account the cost/performance ratio, is reactive melt infiltration. It consists in infiltrating liquid silicon into a porous preform that must contain carbon, so that SiC is produced during infiltration. This chemical reaction is, in fact, the driving force of the process. In the present work, the synthesis of two SiC-based composite materials with very different applications and microstructures has been studied and optimized. In both cases, materials have been obtained with suitable properties for the selected applications. One of the materials studied is SiCp/Si for protection systems such as armor jackets, and the other one is Cf/SiC for use in braking systems. For the optimization, the dwell time and the atmosphere (Ar or primary vacuum) were used as variables. It has been found that in both preforms the optimum conditions are 1 hour dwell time and a vacuum atmosphere at 1450 °C. The effect of these parameters on microstructure and infiltration kinetics are discussed.
A Mini-Review on the Phytochemistry and Biological Activities of Selected Apocynaceae Plants
Authors: Ekalu Abiche , Ayo Rachael Gbekele-Oluwa , James Habila D. , Hamisu Ibrahim
Published: June 2019

This review aims at studying the phytochemistry and biological activities of some selected Apocynaceae plants. Eleven members of this family were reviewed for their phytochemistry and biological activities. Interestingly, the commonly isolated compounds reported from Mondia whitei (Hook.f.) Skeels, Secondatia floribunda A. DC, Carissa carandas, Tabernaemontana divaricate, Nerium oleander, Wrightia tinctoria, T. divaricate, Alstonia scholaris, Carrisa spinarum Linn, Thevetia peruviana and Caralluma lasiantha were triterpenoids, flavonoids, phytosterols, cardiac glycosides and lignans. All of them exhibited remarkable biological activities, mostly similar to each other. This review provides a detailed insight into the pharmacological activities of these selected members of this family.
Curcumin Attenuates Lead-Induced Cerebellar Toxicity in Rats via Inhibition of Oxidative Stress and Chelating Activity
Authors: Abubakar Kabeer , Mailafiya Maryam Muhammad , Danmaigoro Abubakar , Chiroma Samaila Musa , Rahim Ezamin Abdul Bin , Bakar Zuki Abu
Published: June 2019

Lead (Pb) is a toxic environmental heavy metal that induces serious clinical defect on all organs with the nervous system being the primary target. Curcumin is the main active constituent of turmeric rhizome (Curcuma longa) with strong antioxidant and anti-inflammatory properties. This study is aimed at evaluating the therapeutic potentials of curcumin on Pb-induced neurotoxicity. Thirty six male Sprague Dawley rats were randomly assigned into five (5) groups with 12 rats in the control (normal saline) and 6 rats for the lead treated group (LTG) (50 mg/kg lead acetate for 4 weeks), recovery group (RC) (50 mg/kg lead acetate for 4 weeks), treatment group 1 (Cur100) (50 mg/kg lead acetate for 4 weeks, followed by 100 mg/kg curcumin for 4 weeks) and treatment group 2 (Cur200) (50 mg/kg lead acetate for 4 weeks, followed by 200 mg/kg curcumin for 4 weeks) groups each. All experimental groups received the oral treatments through orogastric-tube on alternate days. Motor function was assessed using horizontal bar method while Pb concentration in the cerebellum of the rats were evaluated using ICP-MS techniques. Pb-administered rats showed significant decrease in motor scores, SOD activity with increase MDA levels and Pb concentration in their cerebellum with marked alterations in the histological architecture of the cerebellar cortex layers. However, treatment with curcumin improved the motor score, reduced Pb concentration in the cerebellum and ameliorates the markers of oxidative stress as well as restored the histological architecture of the cerebellum. The results this in study suggested that curcumin attenuates Pb-induced neurotoxicity via inhibition of oxidative stress and chelating activity.
On 2-Inner Product Spaces and Reproducing Kernel Property
Authors: Hashemi Sababe Saeed
Published: June 2019

This paper is devoted to the study of reproducing kernels on 2-inner product Hilbert spaces. We focus on a new structure to produce reproducing kernel Hilbert and Banach spaces. According to multi-variable computing, this structures can be useful in electrocardiographs, machine learning and economy
Carbon Dioxide Emission Prediction of Four CIS Countries by Applying a Correlation and GMDH Artificial Neural Network
Authors: Ahmadi Mohammad Hossein , Ramezanizadeh Mahdi , Alhuyi Nazari Mohammad , Kheradmand Simin , Shamshirband Shahab
Published: June 2019

Increase in the emission of Greenhouse Gases (GHS) is among the significant concerns of government, societies, and policymakers. Due to the highest share of carbon dioxide in the produced GHGs, it is necessary to assess the factors that influence its emission. Energy systems and economic activities noticeably influence the amount of carbon dioxide production of countries. In this article, Artificial Neural Network (ANN) in addition to a linear correlation used to predict carbon dioxide emission of four CIS countries, including Turkmenistan, Uzbekistan, Kazakhstan, and Azerbaijan based the consumption of various energy sources and GDP, as the economic indicator. According to the obtained data by the proposed models, carbon dioxide emission can be accurately estimated by utilizing the mentioned input data. Models’ R-squared value are 0.9997 and 0.9999 in the cases of applying the correlation and ANN-based model. Moreover, the average absolute relative deviations by utilizing the correlation and GMDH ANN are approximately 1.05% and 0.61%, respectively. These statistical values demonstrate more proper performance of the ANN-based model compared with the applied linear correlation.
Gene Expression Comparison Between the Lymph Node-Positive and Negative Reveals a Peculiar Immune-microenvironment Signature and a Theranostic Role for WNT Targeting in Pancreatic Ductal Adenocarcinoma: A Pilot Study
Authors: Argentiero Antonella , De Summa Simona , Di Fonte Roberta , Iacobazzi Rosa Maria , Porcelli Letizia , da via matteo claudio , Brunetti Oronzo , Azzariti Amalia , Silvestris Nicola , SOLIMANDO ANTONIO GIOVANNI
Published: June 2019

Over the past several years there has been much debate with regards to the prognostic and clinical significance of pancreatic ductal adenocarcinoma (PDAC) with lymph nodes metastasis. The PDAC gene-expression knowledge and the biologic alterations underlying the lymph node involvement convey a clinical implication in dealing with the theranostic window.To this end, we provide an original bioinformatic dissection of the gene-expression differences of PDAC according to the nodal involvement from a large public available dataset. Comprehensive transcriptomic analysis from 143 RNA-seq patient’s derived samples indicated that WNT increased activation and a peculiar immune-microenvironment identify subjects with nodal involvement.In frame of this thinking, we validated the WNT pathway role in increasing the likelihood of lymphatic dissemination in vitro. Moreover, we demonstrated for the first time in a PDAC model the potential therapeutic window that XAV-939, a specific WNT pathway inhibitor, has in re-educating a tumour permissive immune system. Finally, we outline the potential implication on bystander molecular drivers exerted by WNT molecular inhibition, providing a picture of the proteomic oncogenic landscape changes elicited by XAV-939 on PDAC cells and their clinical implication. Our findings hold the promise to identify novel immune-based therapeutic strategies targeting WNT to enhance PDAC cytotoxicity and restore anti-PDAC immunity in nodes-positive disease.
Seysmic Vulnerability and the Old Towns: A Cost-Based Programming Model
Authors: Giuffrida Salvatore , Macca Valentina , Circo Chiara , Giuffrè Margherita , Trovato Maria Rosa , Ventura Vittoria
Published: June 2019

Vulnerability is the big issue of the small inland urban centers exposed to the risk of depopulation. In the climate and in the context of an increasing seismic risk in the center-northern part of Italy, seismic vulnerability can become the determinant cause of the final abandonment of a small town. In some Italian regions, as well as Emilia Romagna, municipalities are implementing seismic vulnerability reduction policies based on the Emergency Limit Condition that has become a basic reference for ordinary land planning. This study proposes a valuation planning approach to the seismic vulnerability reduction carried out within the general planning framework concerning the Faentina Union, a group of five small towns located in the south-western part of the Province of Ravenna, Italy. The approach consists of three main stages: knowledge – the typological, constructive and technological description of the buildings specifically concerning their vulnerability degree; interpretation – the analyses aimed to outline a range of hypotheses about the damages in case of seism; planning – identifying the works intended to definitely reduce the vulnerability of the buildings. This stage includes a cost modelling tools aimed at outlining the trade-off between the extension and the intensity of the vulnerability reduction works, given the budget.
Infinitesimal Transformations of Locally Conformal Kähler Manifolds
Authors: Cherevko Yevhen , Berezovski Volodymyr , Hinterleitner Irena , Smetanová Dana
Published: June 2019

The article is devoted to infinitesimal transformations. We have obtained that LCK-manifolds do not admit nontrivial infinitesimal projective transformations. Then we study infinitesimal conformal transformations of LCK-manifolds. We have found the expression for the Lie derivative of a Lee form. Also we have obtained the system of partial differential equations for the transformations, and explored its integrability conditions. Hence we have got the necessary and sufficient conditions in order that the an LCK-manifold admits a group of conformal motions. Also we have calculated the number of parameters which the group depends on. We have proved that a group of conformal motions admitted by an LCK-manifold is isomorphic to a homothetic group admitted by corresponding K\"{a}hlerian metric. We also established that an isometric group of an LCK-manifold is isomorphic to a some subgroup of homothetic group of the coresponding local K\"{a}hlerian metric.
Photocatalytic Degradation of Azo Dye Reactive Violet 5 on Fe-Doped Titania Catalysts under Visible Light Irradiation
Authors: Zuorro Antonio , Lavecchia Roberto , Monaco Marika Michela , Iervolino Giuseppina , Vaiano Vincenzo
Published: June 2019

The presence of azo dyes in textile effluents is an issue of major concern due to their potential impact on the environment and human health. In this study we investigate the photocatalytic degradation under visible light of Reactive Violet 5 (RV5), an azo dye widely used in the textile industry. A preliminary screening of different titania-based catalysts was carried out to identify the best candidate for RV5 removal. The selected catalyst was then tested in a stirred and aerated lab-scale reactor illuminated with a light LED source (λmax = 460 nm). The effects of pH, catalyst load and hydrogen peroxide additions on the efficiency of dye removal were evaluated. Under the best conditions (pH 10, 3 g/L of catalyst and 60 mM hydrogen peroxide), the dye solution was completely decolorized in about 2 h. Overall, the results obtained suggest that the proposed process may represent a suitable method for the removal of RV5 from textile effluents.
Impact of Cefotaxime Non-susceptibility on the Clinical Outcomes of Bacteremic Pneumococcal Pneumonia
Authors: Cilloniz Catia , de la Calle Cristina , Dominedò Crsitina , Garcia-Vidal Carolina , Cardozo Celia , Gabarrus Albert , Marco Francesc , Torres Antoni , Soriano Alex
Published: June 2019

Background: We aimed to analyze the impact of cefotaxime non-susceptibility on the 30-day mortality rate in patients receiving a third-generation cephalosporin for pneumococcal bacteremic pneumonia.
Methods: We conducted a retrospective observational study of prospectively collected data from the Hospital Clinic of Barcelona. All adult patients with monomicrobial bacteremic pneumonia due to Streptococcus pneumoniae and treated with a third-generation cephalosporin from January 1991 to December 2016 were included. Risk factors associated with 30-day mortality were evaluated by univariate and multivariate analyses.
Results: During the study period, 721 eligible episodes were identified, and data on the susceptibility to cefotaxime was obtainable for 690 episodes. Sixty six (10%) cases were due to a cefotaxime non-susceptible strain with a 30-day mortality rate of 8%. Variables associated with 30-day mortality were age, chronic liver disease, septic shock, and the McCabe score. Infection by a cefotaxime non-susceptible S. pneumoniae did not increase the mortality rate.
Conclusion: Despite the prevalence of cefotaxime non-susceptible S. pneumoniae has increased in recent years. We found no evidence to suggest that patients hospitalized with bacteremic pneumonia due to these strains had worse clinical outcomes than patients with susceptible strains.
Chemical and Biochemical Onslaught of Anthropogenic Airborne Species on the Heritage Monument, the Taj Mahal
Authors: Banerjee Deepankar , Sarkar Sabyasachi
Published: June 2019

The science on the anthropogenic airborne aerosols impacting upon the World Heritage marble monument, the Taj Mahal, at Agra has been studied in the light of modern physico-chemical approaches. The study is an effort to understand yet unrecognized airborne species which were found on the surface of the Taj Mahal monument. These species have been analyzed in the light of current analytical methods to impart characterization features and their possible impacts on the surface of the marble. Chemical constituents of these substrates which were incorporated over the top surface of the monument have been identified. Interestingly, the carbon particulates which were thought in the micro level, popularly called “particulate matters” has now been identified even in the nano domain entity, which are chemically more reactive, have been found on the surface of the monument. Because of their high chemical activity these nano carbons do play newer chemistry in the presence of air and sunlight generating several reactive oxygen species (ROS).These ROS are capable to respond to complicated chemical reactions on the surface of the marble in association with deposited cyanophyceae and other deposits of plant origin causing rapid degradation. This study provides the nature of onslaught borne out by such monument exposed under the prevalent smoggy environmental scenario.
Moisture Estimation in Cabinet Dryer with Thin-Layer Relationships Using Genetic Algorithm and Neural Network
Authors: Maleki Behzad , Ghazvini Mahyar , Ahmadi Mohammad Hossein , Maddah Heydar , Shamshirband Shahab
Published: June 2019

Nowadays industrial dryers are used instead of traditional methods for drying. In designing dryers suitable for controlling the process of drying and reaching a high quality product, it is necessary to predict the instantaneous moisture loss during drying. For this purpose, ten mathematical-experimental models with a neural network model based on the kinetic data of pistachio drying are studied. The data obtained from the cabinet dryer will be evaluated at four temperatures of inlet air and different air velocities. The pistachio seeds will be placed in a thin layer on an aluminum sheet on a drying tray and weighed by a scale attached to the computer at different times. In the neural network, data are divided into three parts: educational (60%), validation (20%) and test (20%). Finally, the best mathematical-experimental model using genetic algorithm and the best neural network structure for predicting instantaneous moisture are selected based on the least squared error and the highest correlation coefficient.
Potential of Renewable Energy Biogas from Plant (Hyacinth)
Authors: Riswanto Riswanto , Sodikin Sodikin
Published: June 2019

Energy is one of the basic human needs, both in the form of electricity and energy in the form of heat / gas. The increase in Indonesia's population has increased by 1.3% every year, this is comparable to the increase in energy needs. Current conditions illustrate that the fulfillment of energy needs is sourced more from fossil materials that cannot be renewed, therefore a solution is needed to overcome these problems by finding and finding potential alternative energy sources that can meet human needs. One of the energy that can be utilized is biogas. Biogas is a process of fermentation of organic matter that produces methane gas. Organic materials available in nature are abundant, one of which is organic matter derived from water hyacinth. For this reason, a research study is needed by identifying the potential of biogas energy from water hyacinth. This research is an experimental research, the data collection technique is done by quantitative methods. The tools needed are a manometer, thermometer and biogas reactor. This research was conducted by measuring the temperature and pressure produced by biogas made from organic water hyacinth. The results obtained showed that the biogas produced from water hyacinth produced a gas odor that was relatively not too stinging and the gas formation process was faster. Gas pressure measurements are carried out using a monometer by calculating the difference in the height of water pressure in the U pipe. Measurements of pressure changes are carried out for 20 days by conditioning external factors such as temperature and humidity. The study was conducted to examine the effect of adding water hyacinth to biogas organic matter. The results obtained that t count> t table is the value of t arithmetic (8.183)> t table (2.093) and the significance level of 0.000 <0.05. This means that there are differences in biogas production between before adding water hyacinth and after adding water hyacinth.
FAKTOR-FAKTOR YANG MEMPENGARUHI PENGUNGKAPAN EMISI GAS RUMAH KACA DARI PERSPEKTIF AKUNTANSI HIJAU
Authors: Deantari Sri Anggita Olvin , Pinasti Margani , Herwiyanti Eliada
Published: June 2019

This study aims to analyze the effect of environmental management system, environmental performance, size, profitability and leverage to greenhouse gas emissions disclosure in Indonesia companies. To measure the extent of carbon emission disclosure used checklist that was developed based on the information request sheets provided by the carbon disclosure project (CDP). The population of this study was all basic industrial and chemical companies listed on the Indonesia Stock Exchange during 2014-2016. Sampling method used in this research is purposive sampling method so that obtained samples based on the criteria as many as 60 research samples. Type of data used is secondary data. Data analysis used descriptive statistic, Classical Assumption Test, Multiple Linear Regression Analysis, Goodness of Fit Test, Coefficient of Determination Analysis (R²) and Hypothesis Testing (t test). The results of 5 hypothesis, 4 hypothesis accepted and 1 hypothesis rejected. Variable Environmental Management System, Environmental Performance and Size have positive and significant and Leverage have negative and significant impact to carbon emission disclosure. While profitability have positive but not significant impact in basic industrial and chemical companies in Indonesia. Based on Adjusted R Square is seen that the value of coefficient of determination is 0.663, it means that the Greenhouse Gas Emission Disclosure can be explained by independent variable equal to 66,3% and 33,7% explained by other variable.
AKTUALISASI BISNIS DAN PEMBIAYAAN BERLABEL SYARIAH
Authors: Itmam Shohibul
Published: June 2019

This paper describes a business and financing labeled sharia that is currently reaping controversy in its actualization. This business practice and financing labeled sharia is different from conventional banking or financial institutions. Sharia labeled business practices and financing were initially present as a choice and solution for Muslims who want to avoid the practice of banks or conventional financial institutions that use the ribawi system which can then be an option for other Muslims. The focus of the writing is to question the actualization and existence of sharia-labeled institutions whether they are correct in substance and reflect sharia. The results of the writing are that the implementation of sharia-labeled businesses such as sharia financial institutions (LKS) still exists in substance practices so that business stakeholders are obliged to be sharia-responsible to not only practice usury-free LKS but must also be free from elements of the Shariah like gambling, speculation and so on. Islam commands to stay away from these things because it is considered as doing wrongdoing or damage. Sharia-labeled businesses and financing that are not yet appropriate are demanded not only purely business which aims to make profits as high as high by putting aside the substance of sharia but also must have the principle of mashlahah for stakeholders. Sharia business and labeling in order to remain in sharia principles whose operations are a shared responsibility between managers and state institutions appointed to carry out sharia-labeled business and financing processes and procedures in the right and correct corridors and do not engineer sharia which is merely a figment of impersonation sharia.