bluuebunny/crossref_metadata_2025 huggingface dataset:
Studi Komparatif Daya Dukung Pondasi Tiang Pancang Berdasarkan Hasil Pile Driving Analyzer Test dan N-SPT
Authors: Zulfiqar Muhammad , Hudori Mahfuz
Published: September 2023

The construction of the skidway in the southern part was planned using a pile foundation on the lower structure. Piles are used to channel the load received by the above part of the structure into the ground. The foundation of the structure must have a mast carrying capacity greater than the plan load that the foundation is capable of accepting. This research is important to find out whether the different methods implemented in the field produce different soil carrying capacity. This research will discuss the comparison of pile carrying capacity with field data and testing the carrying capacity of pole foundations. The method of accurate carrying capacity measurement is carried out by static loading with a test method with a loading scale of 2-3 times the planned load. Another method that can be done is HSDPT, which is a high strain dynamics pile test or a pile driving analyzer (PDA) Test. The test results of the analysis showed that there was only a 1% difference in results through an empirical approach with testing with CAPWAP and PDA tests on the southern cpp deck expansion project. The conclusion of this research that the difference in the method used does not have a large enough deviation to the results obtained when construction is carried out in the field.
Analisa Kinerja Lalu Lintas Simpang Tiga Tidak Bersinyal Studi Kasus Jalan KH Ismail Malik-Jalan Raden Syahbudin Kota Jambi
Authors: Silaban Hendra Hasudungan , Das Amsori M , Setiawan Ari
Published: September 2023

This study aims to determine traffic performance at intersections using the 2014 PKJI guidelines, so as to determine the capacity value at the intersection and the Degree of Saturation value to continue research by providing solutions to the problems that occur. This research method uses PKJI 2014 guidelines to obtain vehicle volume and road width values at the research location for further analysis. it is known that the peak hour with a total volume value (Q) of 2010.8 cur/hour, a capacity value (C) of 2203 cur/hour, degree of saturation (Dj) = 0.91, delay (T) = 15.96 sec/ cur and the value of the Queue Opportunity (PA) (65.53% - 33.22%). Judging from the results of the degree of saturation, the location of this study did not meet the requirements in the 2014 PKJI, where if the value of the degree of saturation was ≥ 0.85, a design change was required. The service level in this study was C (15.1 – 25.0) in the medium category. After re-calculation by redesigning the width of the minor road approach, moving the market, installing prohibited parking signs along the intersection approach and recommending the placement of bus routes at this research location, assuming the bus passengers are full. Then the resulting value of Capacity (C) is 2319.7 cur/hour, with a Degree of Saturation (Dj) value of 0.84. Where the Dj value meets the requirements of the Indonesian Road Capacity Guidelines (PKJI 2014).
Identifikasi Faktor-Faktor Iklim Keselamatan Kerja terhadap Kinerja Keselamatan Kerja pada Proyek Konstruksi Di Provinsi Jambi
Authors: Kutni Darul , Carlo Nasfryzal , Utama Wayudi P
Published: September 2023

Even though the construction sector provides business opportunities for workers, this sector also contributes 30% -40% of accidents and fatalities. For this reason, it is necessary to identify the factors of the work safety climate and their influence on work safety performance. This study aims to identify and measure the work safety factors and safety performance and which dominantly improves safety performance. The third aim to evaluate the relationship model between work safety climate and work safety performance. This research adopts 45 safety climate variables Zahoor, 2017 and uses 275 construction workers in Jambi Province. The data collection techniques with primary (informants) and secondary data (K3 documents and literature studies) utilize observation, direct interviews, and questionnaires. The results study found that the first three factors form the work safety factor (FIK1, FIK 2, FIK3). For  named FIK1 to become Management Commitment and OSH resources, Procedures and Awareness of FIK2, FIK3 is named Perception of Accidents. In the second stage, the research found only factor 3 or IK3, namely the Perception of Accidents that affected safety performance. In the third stage, the study found that the safety performance measurement model only had the third factor, namely the Perception of Accidents, which could be used in a structural equation model that affected safety performance. Hopefully that understanding and knowing the observed variables from CI can help the project management team design the right strategy to create a safe project environment.
Pengaruh Penambahan Aditif Sikament-Ln terhadap Kuat Tekan Beton Mutu Tinggi dengan Variasi Nilai Slump
Authors: Ibrahim Ibrahim , Kosim Kosim , Razhanah Firdha , Nugraha Reynaldy Aji , Fahruddin R. Reza
Published: September 2023

High-strength concrete listed in SNI 03-6468-2000 concrete is defined as concrete having the required compressive strength of fc'≥ 41 Mpa. From this study, data obtained from the compressive strength of concrete at the age of 28 days as follows: the value of the normal concrete compressive strength of 41.72 MPa, the compressive strength of the Sikament-ln mixture of 0.6% slump 5 of 45.65 MPa, the compressive strength of the Sikament-mixed concrete. -ln 1% slump 6 of 47,38 MPa, compressive strength of mixed concrete Sikament-ln 1.4% slump 7 of 44.20 MPa, compressive strength of mixed concrete of Sikament-ln 1.8% slump 8 of 45.65 MPa 38 ,65MPa. It can be seen from the results of this study that the ideal compressive strength is the compressive strength of the Sikament-ln mixture of 1% slump 6 this is because the compressive strength value is much greater than the compressive strength without the Sikament-ln mixture.
Toxicological characteristics of the probiotic drug Bioseven
Authors: Dyuba A. , Lyasota V.
Published: September 2023

Ukraine's food security is determined by the production of a sufficient number of high-quality, ecologically harmless, complete food products of animal origin. Bacterial preparations based on live microbial cultures - pre and probiotics - have become widely used in most countries of the world, including Ukraine, in the technological process of growing agricultural animals, especially poultry. The purpose of the work was to conduct a toxicological characterization of the probiotic preparation Bioseven. The following research methods were used to obtain scientific information: zootechnical, zoohygienic, morphological, biochemical, statistical. The research was conducted on white Wistar rats of both sexes. Healthy animals with the ap propriate body weight were used in the experiments. Fluctuations in body weight in the respective groups did not exceed ±10.0 %. Animals were kept in groups in cages in compliance with sanitary and hygienic requirements. It was established that when Bioseven was administered to white rats in doses of 1000, 2500, 5000 mg/kg, all animals remained alive and clinically healthy: the behavior of the animals was typical for this species of rodents. Activity, grooming, breathing rate, feed and water consumption in all groups did not differ significantly and were within physiological norms, no signs of intoxication were registered. Under the conditions of intragastric administration of the drug Bioseven LD 50 for white mice and rats is more than 5000 mg/kg of body weight. The use of the drug Bio-seven in the above doses for 30 days leads to kidney and liver damage in the animals of the third experimental group (10-fold dose). The application of the drug Bioseven to the animals of the two experimental groups did not show probable changes in the morphological and biochemical indicators of the blood compared to the control. The level of endogenous intoxication of the body of white rats (SZE) did not change between experimental animals. Thus, the toxicological characteristics of the probiotic preparation Bioseven indicate the absence of a suppressive effect of the probiotic Bioseven on the metabolic processes of the body of laboratory animals.
Key words: probiotic, toxicological characteristics, suppressive effect, biochemical, ecologically harmless, complete, food products, animal origin, food safety, consumer.
Influence of antibiotic treatment duration on the development of antibiotic resistance
Authors: Shahanenko R. , Kozii N. , Shahanenko V. , Avramenko N. , Taranuha S.
Published: September 2023

Avoidance of unnecessary antimicrobial administration is a key point of antimicrobial stewardship; knowing the optimal duration of therapy obviates over-treatment. In this article we have highlighted the results of modern research on the influence of the duration of antibiotic use on the success of treatment and the development of resistance of microorganisms. Foreign literary sources and the results of scientific research by experts in this field are analyzed. Based on the research results, the following conclusions were made. The results of modern studies on the duration of antibiotic use show that short-course antibiotic therapy is superior to usual long-course antimicrobial treatment. A short course of antibiotic therapy usually leads to the same positive clinical outcomes, a lower rate of antibiotic resistance and the number of clinical relapses. The two most important potential complications associated with the duration of antibiotic therapy are incomplete treatment and the emergence of antibiotic resistance. The time points used for antibiotic treatment (clinical or bacteriological cure, relapses, etc.) are subjective, complex and unreliable. The effectiveness of procalcitonin or other blood parameters for use in monitoring antibiotic treatment requires more focused studies. Despite the high relevance and publicity of various aspects of antibiotic therapy in the practice of human and animal healthcare, research on the efficacy and consequences of short-term antibiotic therapy in veterinary medicine is limited. More attention should be paid to this issue, especially in the field of animal husbandry.
Key words: antibiotic resistance, antibiotic, microorganisms, treatment scheme, animals, duration of antibiotic therapy, clinical result, relapses.
Clinical and pharmacological effectiveness of Fit-O-Metrin drug in the scheme of treatment of bovine postpartum metritis
Authors: Feshchenko D. , Prus V. , Zghozinska O. , Shevchenko A. , Revunets A.
Published: September 2023

The article presents data on the approval of the new Fit-O-Metrin drug for accelerating the recovery of cows from postpartum metritis. The experiment was focused on monitoring the excretion of exudate; restoration and strengthening of the contractile function and regenerative processes in the uterus after the use of the drug. Favorable conditions for uterine disease are often created during calving. However, the reproductive function of animals is mostly determined by the ability to restore the physiological state of the uterus in the postpartum period. Thus, in the experimental farm AgroTsvit 2012 (Zhytomyr region), clinical and laboratory examination of cows in the postpartum period determined that the prevalence of metritis covers up to 42% of the herd. The largest percentage of sick cows had purulent form (53.1 %), catarrhal-purulent metritis was registered in 30.4 %, catarrhal – in 16.5 %. Through our own research, we determined the effectiveness of the experimental drug Fit-O-Metrin, made on the basis of plant materials (extract of thyme, motherwort, and common barberry) for intrauterine administration as part of the treatment regimen for bovine metritis. In the clinical test, 13 sick cows were involved, to which Fit-O-Metrin was applied according to three different schemes. Another 5 animals with metritis were included in the control group, which were treated according to the standard protocol for the farm. However, regardless of the chosen scheme, the complete cessation of the release of inflammatory exudate from the vagina of the entire cow's herd was recorded already on the 6–7 day (in the control group – on the 9 day). Normalization of tone and anatomical position of the uterus, complete closure of the cervical canal was noted on the 8th day (in the control group – on the 12 day). The most optimal scheme of using the herbal preparation against postpartum purulent metritis is 2 days injections, 2 days break, 2 days injections, 2 days break, final injection. A single dose of the FitO-Metrin drug is 30 ml.
Key words: postpartum metritis, Fit-O-Methrin, cattle, treatment scheme, effectiveness, exudate, sexual cycle.
Results of mycotoxicological studies of the influence of sanitary and hygienic conditions on the synthesis of deoxynivalenol by the micromycete F. graminearum on various grain substrates
Authors: Ostrovskiy D. , Zotsenko V. , Grishko V.
Published: September 2023

Today, fusariotoxins play an increasing lyimportant role in the pathology of farm animals, among which deoxynivalenol plays an important role. Deoxynivalenol (DON) is one of the most common fusariotoxins. It affects the health of animals that consume contaminated feed, and can lead to various metabolic disorders, disrupting the body's homeostasis. One of the main effects of deoxynivalenol is that it stimulates the production of anti-inflammatory cytokines, which in turn causes the acute phase of inflammation in animals. In addition, deoxynivalenol leads to a decrease in appetite and can cause hypophagia in animals, which in turn leads to a decrease in daily gains. The direction of the conducted research is aimed at identifying the optimal substrate for the synthesis of deoxynivalenol and its maximum accumulation by the fungus F. graminearum, and also established the optimal parameters for the synthesis of mycotoxin (cultivation temperature, substrate humidity, cultivation period). Grains of the following crops were used as substrates: wheat, rice, corn, barley, oats, rye, millet, peas, soybeans, sunflower, mustard, rapeseed, buckwheat, and flax. Deoxynivalenol in samples was determined by thin-layer chromatography. The production of deoxynivalenol was studied in the temperature ranges of 4, 17, 24, and 28 °C; humidity of the substrate in the range from 14–90% and the duration of cultivation from 1 to 4 weeks. The mycotoxin-producing activity of the fungus F. graminearum isolate 195/1 was largely determined by the studied parameters. The maximum amount of deoxynivalenol was produced at a temperature of 24 ºС, a substrate humidity of 50%, and a duration of cultivation of 24 days. Of the tested substrates, rice was the best for deoxynivalenol production. The obtained results serve as a basis for possible prediction of feed contamination with deoxynivalenol and, in general, will allow to optimize measures to combat mycotoxicosis and thus minimize the possible risks of mycotoxin poisoning of people and animals.
Key words: F. graminearum, grain substrates, deoxynivalenol, cultivation temperature, substrate humidity, duration of cultivation.
Directions and reproduction soil fertility technologies in the post-war period in Ukraine
Authors: Chaika T. , Korotkova I.
Published: September 2023

The article is devoted to the study of the military action's negative consequences on the soil fertility state in Ukraine and directions for their reproduction. The topic actuality is that a third of the arable agricultural lands were affected by military actions, which, taking into account the agrarian direction of production in the eastern and southern regions of Ukraine, threatens a significant decrease in the agricultural products' cultivation. The article aims to substantiate the effectiveness of technologies applied to overcome the affect of military activities on soil fertility reproduction in Ukraine. The study reveals the war negative consequences on the soil structure and properties and argues that it will take hundreds of years to reproduce naturally. The main types of warfare-induced disturbances to soil are defined and described: the soil structure modification (bombs craters, sealing, etc.) and chemical disturbances (pollutants input). Taking into account the existing experience of overcoming the military actions consequences in the agricultural soil reproduction, a certain procedure for reproducing the soil fertility with different degrees and causes of damage is proposed. The options for soil reproduction with a natural integrity of genetic horizons violation and methods of removing contamination with heavy metals (mechanical, physico-chemical, and biological) are considered. For the practical implementation of the proposed measures, an approximate costs' calculation of the soil fertility reproducing from the military actions consequences in Ukraine was made. It has been determined that for the reproduction of soil properties and their suitability for use in agricultural production, the greatest expenses (excluding humanitarian demining) are spent on mechanical melioration (81.8 %). However, the expenses amount depends on the number of shell explosion craters and their caliber, and the methods of reproduction the soil agrochemical properties. The peculiarities of legal regulation in soil conservation and the fertility protection, in determination of damage caused to lands and soils of Ukraine as a result of armed aggression against the country are indicated. The performed calculations will become key evidence in terms of damage amount compensation in lawsuits against the aggressor country.
Key words: toxic elements, bombturbation, demining, basalt tuff, bioremediation, phytoremediation.
Features of obtaining an aseptic culture of Prunus dulcis (Mill.) D.A. Webb.
Authors: Shita О.
Published: September 2023

The purpose of the presented article is to establish the features of obtaining an aseptic culture of regenerants of Prunus dulcis in vitro. Since the impact of climate change is becoming increasingly large-scale in Ukraine, one of the urgent problems that hinders humanity, both in terms of agro-ecology and food, is the need to diversify traditional agriculture. Mydal is one of the valuable promising nut crops in Ukraine, thanks to which it is possible to diversify the climatic risks listed above. The varieties of domestic selection were taken for experiments, since foreign selection with low winter resistance and a long growing season are not suitable for our zone. Four intensive new varieties of almonds E5 Borozan, M41 Alex, Georgia, Louise, which were bred by breeder V.M. Babanskyi and entered into the State Register of Plant Varieties, and allowed in Ukraine for cultivation. One of the reliable methods of reproduction is microclonal reproduction, with the help of which it is possible to quickly obtain high-quality, disease-free planting material. Therefore, for the production of planting material, modern nurseries are switching to biotechnological methods. It was established that the preparation of explant donors reduces the number of primary explants that released phenolic substances. In addition to the preparation of donors, nutrients, which were present in different amounts in nutrient media with different composition, had a significant impact. The fewest explants with phenol-like exudate were on NAM and NRM media.Common to these two environments is a relatively low content of nitrogen in both ammonium and nitrate forms, and the DKW environment contains the highest amount of sulfur. The release of phenol-like exudate also depended on the biological characteristics of almond varieties. The highest number of primary explants was in the high-growing variety E5 Borozan, and the least in the variety Louise with medium growth intensity. Depending on the variety, 81–91 % were free from contaminants in the depository, while 59–70 % were in control. Morphogenic and at the same time without signs of contamination were found from 69 % among the explants of the Louise variety and up to 73 % of the E5 Borozan variety, compared to 35 and 51 %, respectively, in the control. Based on the results of the research, it was established that the influence of the time of isolation of the primary explants and the features of the interaction of the plant and its surrounding microbiota in different seasons are different. This is manifested in the features of contamination by these objects of primary explants and, accordingly, the success of decontamination (E1) and the appearance of microbiological contamination on the nutrient medium.
Key words: microclonal propagation, nut crops, multiplication, morphogenesis, contaminants, decontamination.
Pros and cons of no-till technology
Authors: Yeshchenko V. , Koval G. , Naklyoka O.
Published: September 2023

The article presents the history of the development and implementation of No-till technology abroad and in Ukraine, indicating the countries and years where and when this technology was developed and implemented. It is indicated that a great contribution to the development of the theoretical foundations of minimization of soil cultivation due to No-till technology was made by the scientists of the USA, who, according to most indicators, highly rated this technology. Among its shortcomings, they attributed the deterioration of the ecological situation due to weeds, diseases and pests and the need to apply higher doses of nitrogen fertilizers and herbicides. Scientists of the National Research Center "Institute of Agriculture" of the Ukrainian Academy of Sciences add to this list a delay of three to four days with the spring ripening of the soil due to the presence of plant remains in the form of mulch on its surface and the spread of mouse-like rodents. This limitation of the disadvantages of No-till technology makes it quite successful in terms of spread in agricultural production, because annually its area in the world grows by more than 1 million hectares. Its largest areas are in the USA, Brazil, Argentina, Canada, Australia and Paraguay, and in Brazil, no-till technology is included in the ranks of government programs with appropriate crediting. In Europe as a whole, the share of land with No-till technology in the structure of sown areas does not exceed 3 %. The optimal conditions for No-till technology in the forest-steppe and steppe zones of Ukraine are on an area of 5.25 million hectares, but its development is currently far from 1 million hectares. The problem of the prevalence of no-till technology in domestic production is seen by the majority of scientists as excessive weediness of the crops grown for it, although in our opinion this phenomenon is possible only in the early stages of the development of the technology without tillage. No-till technology has its future, because only it, among many other technologies, can guarantee an extended reproduction of soil fertility.
Key words: No-till technology, weediness of sowing, soil fertility.
Formation of spike length and number of spikelets in soft winter wheat varieties depending on the genotype and conditions of the year
Authors: Kumanska Yu. , Lozinskiy M. , Sabadyn V. , Sydorova I. , Dubovyk N.
Published: September 2023

The value of the variety in increasing the yield of soft winter wheat is undeniable. Therefore, the use of genetic patterns in breeding can improve the adaptability of modern varieties. In breeding and genetic studies, the formation of yield is considered as a complex characteristic due to many components. Studying the variability and stability of the main structural elements of productivity is an important task in the selection of soft winter wheat. The aim of the study was to investigate the peculiarities of the formation in soft winter wheat spike length and the number of spikelets in it depending on the genotype and the conditions of the year, and to select genotypes with a consistently high expression for involvement in the selection process. The research was carried out in the conditions of the experimental feld of the Educational and Production Center of the Bila Tserkva National Agrarian University in 2018–2020. The source material for the research was varieties of different ecological and geographical origin recommended for growing in Ukrainian forest-steppe. Arithmetic mean ( ), minimum and maximum value of features (min–max), standard deviation (s), coefcient of variation (V, %), homeostatic index (Hom) were determined. To characterize moisture availability, the hydrothermal coefcient was calculated. According to the research results, such varieties as Tobak, Bohemia, Kvitka poliov, Legenda bilotserkivska, Svitilo, Platin, Kolonia, Akratos formed the largest spike length, exceeding the standard variety Lisova pisnia by 1.6– 2.3 cm. A high homeostatic index was determined by this feature in varieties Kvitka poliov (758), Kolonia (343), Svitilo (334), Perlyna Lisostepu (204). The varieties Akratos, Favorite, Kolonia, Svitilo, Platin, Legenda Bilotserkivska, Tobak were selected according to the number of in the ear, which had indicators from 19.0 to 20.4 pcs., which is 2.1–3.5 pcs. more than the standard sort (16.9 pcs.). The highest homeostaticity, in terms of the number spikelets in the spike, was received in Skagen (930), Kolonia (826), Flower of the Fields (780), Akratos (682), and Forest Song (461).
Key words: soft winter wheat, variety, spike length, number of spikelets in the spike, homeostatics, selection.
Formation of varietal resources of winter wheat
Authors: Konovalov D. , Polishchuk V. , Karpuk L. , Chuhleb S. , Skhlyar V.
Published: September 2023

The article highlights the specifcs of the formation of varietal resources of winter wheat in Ukraine. It is shown that the creation of new varieties is a long, laborious and expensive material and intellectual process. The scheme of the selection process of winter wheat is complex and includes at least 12 stages, during which various selection methods are used. Breeding work to create one variety takes 6–12 years. Analysis of the structure of the State Register of Plant Varieties Allowed for Distribution in Ukraine revealed that as of 2022, 661 varieties of winter wheat were entered into the Register, including 470 varieties of Ukrainian selection, which is 71.1 % of their total number. Over the past fve years, the number of winter wheat varieties in the Register of Plant Varieties has increased 1.7 times, from 273 in 2017 to 470 in 2022. During this period, varieties of foreign selection entered the Register more actively, which in 2022 amounted to 28.9 % of the total number, while in 2017 they were 19.9 %. The majority of created varieties – 43.4%, are recommended for distribution in all soil and climatic zones of Ukraine – Steppe, Forest-Steppe and Polissia. By groups of ripeness, the largest number of varieties is 43.5 % medium-ripe and 37.2 % – medium-early varieties. The analysis of the activity of the originators of varieties of domestic breeding showed that the Institute of Plant Physiology and Genetics of the National Academy of Sciences of the Russian Academy of Sciences is the leader, and in 2022, 102 varieties or 21.7 % of the total number of domestic varieties were entered into the Register. The main direction of the selection work of this institute is the creation of plastic varieties of winter wheat for distribution in all zones of Ukraine – steppe, forest-steppe and Polissia, the share of these varieties from their total number is 61.8 %, mainly these are mid-early and mid-ripening varieties. According to the level of productivity and the direction of use, the wheat varieties of the Institute of Plant Physiology and Genetics of the National Academy of Sciences of Ukraine are conditionally divided into two groups: short-stemmed, high-intensity varieties, which under favorable climatic conditions and intensive cultivation technologies are able to form a grain yield of up to 10 t/ha and more, and medium-growing varieties of universal use, which in extreme growing conditions exceed the yield of high-intensity varieties.
Key words: Register of varieties, selection process, maturity groups, distribution of varieties, domestic selection.
The eroded slopes alkalization peculiarities in southern part of western Forest Steppe
Authors: Olifrovych V.
Published: September 2023

A significant part of arable lands on slopes is subject to removal from active processing, and to alkalization with perennial herbs. We know that the most productive are those agro-phytocenoses, forming based on a single-species sowing of alfalfa (Lucerne), and its mixture with perennial cereal grasses. However, the restrictive factor of forming alfalfa-cereal grasslands high productivity is the soil solution acid reaction. The research carried out in 2017–2020 showed that lime application has significantly affected the soil solution reaction. Almost in all variants with liming, the values approached neutral. Besides, the soil liming was an effective factor of the researched grasslands productivity increase. So, a herbal mixture: red clover + alfalfa + timothy grass, on the background without liming and introducing phosphorus-potassium fertilizers, averagely for 2017–2020 has provided the output of 5,93 t/ ha of dry matter. On deacidified plots, the given herbal mixture productivity has increased to 7,52 t/ha of dry matter. The combination of soil liming and phosphorus-potassium fertilizers application has supplied the maximum dry matter output from the herbal mixture: red clover + alfalfa + smooth bromegrass – 8,66 t/ha, which exceeded by 27,5 % the unfertilized variant. The soil chemical melioration and phosphorus-potassium fertilizers application have proved to be the important factors of increasing the leguminous components part in the botanical component of a green mass yield. Particularly, in the most productive herbal mixture: red clover + alfalfa + smooth bromegrass, on the limed and fertilized background, a leguminous component part in the first and second mowings has increased by 20,9 and 17,4 %, respectively. Thus, the legume-cereal grasslands averagely for the first four years of usage provide the 5,93–8,66 t/ ha dry matter output, containing 32–63,8 % of a leguminous component. The soil chemical melioration, as well as phosphorus-potassium fertilizers application have increased the legume-cereal grasslands productivity by 27,5–27,9 %, and enlarged the leguminous components part by 17,4–20,9 %.
Key words: sloping lands, soil liming, herbal mixture, alfalfa (Lucerne), timothy grass, smooth bromegrass, productivity, botanical composition.
Application of Floquet-Magnus Expansion During the Phase Modulated Lee-Goldburg Radiation in Solid State NMR
Authors:   PH. D Program of Physics & PH. D Program of Chemistry, Graduate Center, The City University of New York, NY, USA, Mananga Eugene Stephane , Diop Aissata ,   Department of Engineering, Physics, and Technology, BCC, The City University of New York, NY, USA, Dongomale Paulin J. ,   Department of Geosciences and Geological and Petroleum Engineering, Missouri University of Science and Technology, MO, USA, Donkor Lailatu ,   Department of Engineering, Physics, and Technology, BCC, The City University of New York, NY, USA, Hollington Akil ,   Department of Chemistry, Syracuse University, NY, USA
Published: September 2023

This work uses the Floquet-Magnus expansion approach to investigate the spin system evolution during the phase modulate Lee-Goldburg radiation experiment. Until now, the Frequency switched LeeGoldburg and its variant called the Phase module Lee-Goldburg have been treated by only the average Hamiltonian theory and the bimodal Floquet approach. In this article, we use the expansion schemes of the Floquet-Magnus expansion to calculate the effective Hamiltonian and propagator during the spin dynamics. We present a remarkable iterative approach for the Floquet-Magnus expansion. Our work unifies and generalizes existing results of the Floquet-Magnus expansion and delivers illustrations of novel springs that boost previous applications that are based on the classical information. The method presented could plays a major role in the interpretation of a number of fine NMR experiments in solids, which provide significant new insight in spin physics. The generality of the work points to potential applications in problems related in solid-state NMR and theoretical developments of spectroscopy as well as interdisciplinary research areas whenever they include spin dynamics concepts. The considered method of Floquet-Magnus expansion has recently found new major areas of applications such as in topological materials..
New Class of Genes in D. melanogaster (Conditional Mutations, Ontogenes, and Biological Role of Ontogenes)
Authors:   Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090 Russian Federation, Chadov B. F. , Fedorova N. B. ,   Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090 Russian Federation
Published: September 2023

The review briefs the history of the search for non-Mendelian genes, including the rationale for their existence and the methods for their discovery in D. melanogaster. The genes are named ontogenes and their mutations, conditional mutations. Characteristic features of conditional mutations in hybridological experiments have been described. Three separate sections dwell on the experimental facts that distinctly outline the difference of this novel group of genes from the classical protein-coding (Mendelian) genes. According to these facts, the specificity in the function of ontogenes consists in (1) the warrant that an organism belongs to a particular species; (2) the control of cellular construction; and, most likely, (3) the presence of nonchemical (biophysical) way of interaction between ontogenes
Enhancing Classroom Learning Outcomes: The Power of Immediate Feedback Strategy
Authors: Ajogbeje Oke James
Published: September 2023

The study investigates the effects of using immediate feedback as a teaching strategy. Additionally, the impacts of immediate feedback and gender on students' classroom learning outcomes were examined. The study was designed as a quasi-experimental, pretest-posttest, experimental, and control group. The sample consisted of 225 junior secondary school level 2 (JSS 2) students. Students were chosen from two intact coeducational classes and split into experimental and control groups. All relevant data was collected using a study tool called the Science, Technology, English Language & Mathematics Achievement Test-Questionnaire (STEMAT-Q), which was developed, validated, and used. Data collected were analysed using the mean, standard deviation, Student's t-test, and analysis of covariance (ANCOVA). The study's findings demonstrate that an immediate feedback technique significantly affects the learning outcomes of students. However, for treated male and female students, the interaction effects of the immediate feedback technique and gender on classroom learning outcomes were not significant. Immediate feedback is particularly successful at addressing student confusion, correcting errors, identifying learning gaps, bridging gender differences in student learning outcomes, and inspiring students to learn well. Based on the above findings, the researcher recommends the provision of immediate feedback for students during the learning process or class discussion or activities to enhance their learning skills and help them retain key concepts, ideas, and principles.
PENERAPAN ETIKA BISNIS DENGAN PRINSIP MAQASHID SYARIAH PADA USAHA MINUMAN
Authors: Haslinah Haslinah , Arafah Muh. , Desti Desti , Miar Miar
Published: September 2023

AbstractThe trend of consuming contemporary drinks among today's youth has great potential to increase the amount of contemporary beverage consumption in Indonesia. With the mushrooming of drink outlets in various cities, it is proof that the audience is increasing. This study aims to find out how the application of business ethics with maqashid sharia principles to contemporary beverage businesses. This study uses a descriptive qualitative approach and is a type of field study research. Data collection techniques were carried out by observation and interviews with beverage business owners and employees. The results of the study found that the process and application of business ethics in producing drinks had been carried out well, but in the case of hifdzu al-aql in maintaining reason it had not been carried out properly, prospective employees should have been taught how to produce drinks from the initial stage to the end during the training. properly, as well as in terms of hifdzu an-nasl protecting offspring, we must not lose consumer confidence, especially in terms of good servants. As Muslim business people, in running their business, they should apply business ethics properly and according to the provisions in the Qur'an, hadith and other Islamic sources.Keywords: Business Ethics, Maqashid Sharia, Beverage Business, Production, Consumers Abstrak Tren mengkonsumsi minuman kekinian pada kalangan muda zaman sekarang sangat berpotensi besar guna meningkatkan jumlah konsumsi minuman kekinian di Indonesia. Dengan menjamurnya gerai minuman di berbagai kota menjadi bukti bahwa penikmatnya semakin meningkat. Penelitian ini bertujuan untuk mengetahui bagaimana penerapan etika bisnis dengan prinsip maqashid syariah pada usaha minuman kekinian. Penelitian ini menggunakan pendekatan kualitatif deskriptif dan jenis penelitian studi lapangan, Teknik pengumpulan data dilakukan dengan observasi dan wawancara dengan pemilik dan karyawan usaha minuman. Hasil penelitian didapat bahwa proses dan penerapan etika bisnis dalam memproduksi minuman sudah dijalankan dengan baik, akan tetapi dalam hal hifdzu al-aql dalam menjaga akal belum terlaksana dengan baik, seharusnya pada saat pelatihan calon karyawan sudah diajarkan bagaimana cara memproduksi minuman mulai tahap awal hingga akhir dengan baik, serta dalam hal hifdzu an-nasl menjaga keturunan, kita tidak boleh menghilangkan kepercayaan konsumen terutama dalam hal pelayan yang baik. Sebagai pelaku bisnis muslim dalam menjalankan bisnisnya seharusnya menerapkan etika bisnis dengan baik dan sesuai ketetapan dalam Al-Qur’an, hadis dan sumber Islam lainnya.Kata kunci: Etika Bisnis, Maqashid Syariah, Usaha Minuman, Produksi, Konsumen
Altered blood-brain barrier permeability and its effect on the distribution of Evans blue and sodium fluorescein in the rat brain applied by intracarotid injection.
Authors: Kozler P , Pokorný J
Published: September 2023

The aim was to study the blood-brain permeability according to the distribution in the rat brain of Evans blue (EB) and sodium fluorescein (NaFl) administered by an intracarotid injection. Eighteen animals were divided into six groups according to the state of the blood-brain barrier (BBB) at the moment when the dyes were being applied. In the first two groups, the BBB was intact, in groups 3 and 4 the barrier had been opened osmotically prior to the application of the dyes, and in groups 5 and 6 a cellular edema was induced by hyperhydration before administration of the dyes. The intracellular and extracellular distribution of the dyes was studied by fluorescence microscopy. The histological picture thus represented the morphological correlate of the way BBB permeability had been changed before the application of the dyes.
Frequency-domain lifetime fluorometry of double-labeled creatine kinase.
Authors: Gregor M , Kubala M , Amler E , Mejsnar J
Published: September 2023

Myofibril-bound creatine kinase EC 2.7.3.2 (CK), a key enzyme of muscle energy metabolism, has been selected for studies of conformational changes that underlie the cellular control of enzyme activity. For fluorescence spectroscopy measurements, the CK molecule was double-labeled with IAF (5-iodoacetamidofluorescein) and ErITC (erythrosin 5'-isothiocyanate). Measurement of fluorescence resonance energy transfer (FRET) from fluorescein to erythrosin was used to obtain information about the donor-acceptor pair distance. Frequency-domain lifetime measurements evaluate the donor-acceptor distance in the native CK molecule as 7.8 nm. The Förster radius equals 5.3 nm with the resolution range from 0.2 to 1.0 nm. Erythrosin-fluorescein labeling (EFL) was tested for artificial conformational changes of the CK molecule with high-salt concentration treatment. The transition distance, defined by His-97 and Cys-283 and derived from a 3D model equals 0.766 nm for the open (inactive) form and 0.277 nm for the closed (reactive) form of the CK molecule. In this way, the resolution range of the used spectroscopy method is significant, concerning the difference of 0.489 nm. Nevertheless, the CK enzyme activity, assessed by the hexokinase-coupled assay, was diminished down to 1 % of the activity of the native enzyme. EFL is suitable for description of conformational behavior implied from the regulation of creatine kinase. However, the observed inhibition restricts EFL to studies of conformational changes during natural catalytic activity.
Dynamics of cytokine production in human peripheral blood mononuclear cells stimulated by LPS, or infected by Borrelia.
Authors: Janský L , Reymanová P , Kopecký J
Published: September 2023

To specify the role of individual cytokines in the immune response to pyrogens, isolated and cultivated human peripheral blood mononuclear cells (PBMC) were used for the experiments. Different pyrogens (lipopolysaccharide from Escherichia coli - LPS and live Borrelia afzelii) were applied and the time course of changes in concentrations of different cytokines in the medium was followed using the ELISA method. It was found that nonstimulated human PBMC proliferate under in vitro conditions and produce IL-6, TNF-a, IL-10 and finally also IL-1b. Productions of IL-12 and INF-g are not changed. Proliferation of PBMC is potentiated after incubation with LPS or live Borrelia. PBMC stimulated by LPS increase the net production (stimulated minus unstimulated) of IL-1b and TNF-a significantly, while production of IL-6 was smaller. A delayed increase in the production of IL-10 was also observed. Productions of IL-12 and INF-g were not influenced. In contrast to LPS, stimulation of PBMC with live Borrelia, increases also the production of IL-12 and IFN-g, besides IL-1b, TNF-a, IL-6 and IL-10. Productions of IL-1b, IL-6 and TNFa increased immediately after incubation with both LPS and Borrelia, while productions of IL-12 and INF-g begin to increase 8 hours and production of IL-10 12 hours after stimulation. Data indicate that stimulation with different pyrogens may activate the cells of the immune cascade in a different way. Stimulation of BPMC by LPS seems to activate the initial steps of the immune response (macrophages and granulocytes) only, while infection with live Borrelia also stimulates the later phase of the immune response, probably due to effect of initially produced cytokines.
Kinetics of cardiac RyR channel gating studied at high temporal resolution.
Authors: Dura M , Zahradník I , Zahradníková A
Published: September 2023

Measurements of ryanodine receptor (RyR) activity during dynamic changes of calcium concentration have suggested that RyR has at least four calcium binding sites, and that activation transpires as an increase in the activity within the high open probability H-mode. Binding of several Ca2+ ions within the H-mode should manifest itself in the steady-state RyR activity by the presence of multiple closed times. However, previously only two closed times were detected in the H-mode of RyR activity. Here we recorded steady-state activity of single cardiac RyRs with high temporal resolution and compared it to data simulated under the same conditions using our previously published model of RyR gating. At a 10 kHz resolution, the closed time histograms of both experimental and simulated data had three exponential components. The closed times of simulated data were not significantly different from those obtained experimentally. After filtering at 2 kHz, only two exponential closed time components with time constants not significantly different from those previously published could be detected in both experimental and simulated records. The conformity of the steady-state experimental data to the model derived from the dynamic data provides further support for the idea that RyRs need binding of multiple Ca2+ ions to open.
Action of GABA-B antagonist on cortical epileptic afterdischarges in rats is similar to that of GABA-A antagonist.
Authors: Živanović D , Bernášková K , Kaminskij Yu , Mareš P
Published: September 2023

Threshold intensities for epileptic phenomena induced by cortical stimulation were used for comparison of the action of GABA-B and GABA-A antagonists in rats with implanted electrodes. Both CGP 35348 (200 mg/kg i.p.) and bicuculline (4 mg/kg i.p.) significantly decreased thresholds for spike-and-wave afterdischarges and their motor counterpart (clonic seizures) whilst transition into the second, limbic type of afterdischarge as well as threshold for movements directly bound to stimulation remained uninfluenced by either drug.
IOT BASED GARBAGE MONITORING SYSTEM AND NOTIFICATION APPLICATION
Authors: K Arjun , Manoj H , Gadiyar T , Suthar Darshan , Gowda M J Dev Dutt , Suryanarayana Hegde Vijay , Ahmed Mathin ,   Sri Dharmasthala Manjunatheshwara Institute of Technology
Published: September 2023

: In today's world there is an immense growth in the population of the cities due to this rapid urbanization there is a waste collection that leads to various infectious diseases in the environment. There is a concept with the prototype which we have built that is the Recycle, Reuse, Reduce policies throughout this waste management system. To prevent these bins from becoming overloaded, access to real-time information about each bin is available. The suggested structure lowers personnel costs while also saving the system time and energy. access to each bin's real-time information, preventing overcrowding of these bins. access to each bin's real-time information, preventing overcrowding of these bins. The suggested structure lowers personnel costs while also saving the system time and energy. We mostly utilized Arduino, NODEMCU, Servo Motors, and Ultrasonic Sensors to build this prototype. The software element is the Blynk app, which is utilized to receive notifications. This concept might serve as the foundation for a smart waste disposal system in urban areas.
A RESEARCH PAPER ON ENHANCING ELEARNING EXPERIENCES: A NOVEL DISTRIBUTED MANAGEMENT SYSTEM WITH PRACTICE QUIZ, NOTES PDF, CODE EDITOR, AND DISCUSSION FORUM INTEGRATION
Authors: Singh Jethi Narendra , Singh Binay , Bhandari Ishwar Singh ,   Graphic Era Hill University
Published: September 2023

The advent of e-learning has revolutionized education by providing flexible and accessible learning opportunities. However, many existing e-learning platforms lack certain key features that can enhance the learning experience for students. In this research paper, we present a novel distributed management system for elearning platforms that integrates practice quizzes, notes PDF, code editor, and discussion forums. Our system aims to address the limitations of traditional e-learning platforms such as Udemy, Great Learning, Coursera, W3School, Tutorials Point, E-Council and etc. by offering additional interactive features. We describe the design and implementation of our distributed management system and discuss its potential benefits in terms of student engagement, knowledge retention, and collaborative learning. Furthermore, we conduct a comparative analysis to assess the effectiveness and user satisfaction of our system compared to existing platforms. The results demonstrate the value of our distributed management system in providing a comprehensive e-learning environment that promotes active learning, fosters collaboration, and enhances the overall learning experience. This research contributes to the advancement of e-learning technologies by offering innovative features that bridge the gap between traditional e-learning platforms and the evolving needs of modern learners.