bluuebunny/crossref_metadata_2025 huggingface dataset:
A retrospective analysis of the results of surgical treatment of large macular holes
Authors: Samoylov A N , Fazleeva G A , Khaybrakhmanov T R , Samoylova P A , Fazleeva M A
Published: March 2018

Aim. A retrospective analysis of the results of surgical treatment of large idiopathic macular holes depending on the technique of surgical intervention.

Methods. The results of surgical treatment of 60 patients (60 eyes) with idiopathic macular holes with a diameter of more than 800 μm were studied in the Republican clinical ophthalmology hospital of Kazan. The average age of the patients was 66.2±5.37 (61-74) years. The patients underwent complex ophthalmological examination before the surgery and 10 days and 1 month after the surgery, including visometry, tonometry and optical coherence tomography. Patients were divided into two groups (30 subjects each), comparable in clinical and epidemiological parameters: group 1 - standard surgical tactics, group 2 - surgical treatment according to the method proposed by professor A.N. Samoylov. Visual acuity with correction before surgery in group 1 was 0.11±0.05, in group 2 - 0.12±0.06.

Results. Ten days after the surgery, group 1 had anatomical closure in 23 (76.7%) patients, anatomical result was not achieved in 7 (23.3%) patients. In group 2, complete closure of the rupture was achieved in 27 (90.0%) patients, incomplete - in 3 (10.0%) patients. In 1 month in group 1, complete closure of the macular rupture was observed in 22 (73.3%) patients, in 8 (26.7%) patients the result was not achieved. In group 2, complete closure of the rupture was determined in 28 (93.3%) patients, incomplete closure - in 2 (6.7%) patients. Visual acuity 1 month after the surgery in group 1 was 0.15±0.08, and in group 2 - 0.32±0.11 (p <0.05).

Conclusion. Surgical treatment of large idiopathic macular holes according to the modified technique of the inverted internal limiting membrane flap proposed by professor A.N. Samoylov, provides better anatomical and functional results in comparison with the standard technique (p <0.05).
VAKUM YARDIMLI DOĞUM: NEDEN ÇEKİNİYORUZ?
Authors: Fidan Ulaş , Ulubay Mustafa , Kıncı Mehmet Ferdi , Mutlu Hilmi , Bodur, Serkan , Yenen Müfit Cemal
Published: March 2018

AMAÇ: Vakum ekstraksiyon ile gerçekleşen müdahaleli doğumun kısa dönem klinik sonuçları açısından, sezaryen doğum ile karşılaştırılması.GEREÇ VE YÖNTEM: Çalışma 2015-2016 yılları arasında Gülhane Askeri Tıp Akademisi Kadın Hastalıkları ve Doğum Anabilim Dalında retrospektif kohort olarak yürütülmüştür. Çalışmaya primipar gebeler dahil edilmiştir. Doğumun ikinci evresinin uzaması endikasyonu ile vakum ekstraksiyon yapılarak vajinal doğum gerçekleştirilen gebeler ile baş pelvis uyumsuzluğu nedeniyle sezaryen doğum yapılan gebeler kısa dönem sonuçları (fetal pH, postpartum kan kaybı, maliyet) açısından karşılaştırılmıştır. BULGULAR: Vakum ekstraksiyon yapılan grupta (n:22), sezaryen yapılan gruba (n:30) göre aktif eylem süresi, doğum sonu kan kaybı ve buna bağlı olarak kan transfüzyonu oranları daha fazla iken, tedavi maliyeti daha azdır (p<0,05).SONUÇ: Her ne kadar vakum ekstraksiyon grubunda doğum sonu kanama komplikasyonu daha fazla olsa da, bu konudaki deneyim arttırılmalı ve hekimler vakum ekstraksiyon uygulaması açısından cesaretlendirilmelidir.
APİKAL TROMBÜS İLE SEYREDEN ARİTMOJENİK SAĞ VENTRİKÜL DİSPLAZİSİ KARDİYOMİYOPATİLERİN ATİPİK BULGUSU
Authors: Şafak Özgen , Emren S. Volkan
Published: March 2018

Aritmojenik sağ ventrikül displazisi (ARVD) na-dir görülen bir kardiyomiyopatidir. ARVD ço-ğunlukla genç yaşlarda tanı alır ve kendisini ventriküler aritmiler, çarpıntı, baş dönmesi, kalp yetmezliği ve hatta ani kardiyak ölüm ile gösterebilir. Görüntüleme yöntemleri ile sağ ventrikül (SV) dilatasyonu ve apikal anevrizma tipik bulgusudur. Fakat ARVD olgularında int-raventriküler trombüs çok nadir görülmektedir. 19 yaşında erkek hasta, hastanemize çarpıntı ve bayılma şikâyetleri ile başvurdu. Elektrokar-diyografisinde ön yüz derivasyonlarda T nega-tifliği bulunmakta idi. Ekokardiyografide sağ ventrikül dilate ve SV apeksinde anevrizmatik oluşum içinde trombüs görüldü (Fig-1). Kardi-yak manyetik rezonans incelemede sağ vent-rikül genişlemesini, yağ infiltrasyonunu, fibro-tik dokuları, SV duvar hareket bozukluğunu ve trombüslü apikal anevrizma doğrulandı. Anti-koagulan tedaviyle üç ay sonra trombüsün rezole olduğu gözlendi ve ICD implante edildi. ARVD tanısında elektrokardiyografik, aritmik, histolojik ve ailesel özelliklerin yanında görün-tüleme yöntemleri de büyük önem taşımak-tadır. Sağ ventrikül dilatasyonu ve apikal anev-rizması tanı sürecinde önemli kriterler olmakla birlikte bu gibi bulgular saptandığında trom-büs varlığı da dikkatlice değerlendirilmelid
Proton Pompa İnhibitörü Kullanımının Blastocystis sp.’ in Görülme Sıklığı Üzerine Etkisi
Authors: HIZALER Etem , ŞENOL Vesile , ÇETİNKAYA Ülfet , ŞAHİN İzzet
Published: March 2018

Amaç: Blastocystis sp. insanlarda en sık
görülen intestinal sistem protozoonlarından biridir ve kontamine olmuş
gıdalarla ve su ile fekal oral yolla bulaşmaktadır. Gastrointestinal sistem
hastalıklarında çoğunlukla kullanılan proton pompa inhibitörlerinin (PPI),
midenin pH’nı yükselttiği bilinmektedir. Bu çalışma, PPI kullanımının Blastocystis
sp.’nin görülme sıklığı üzerine etkisini araştırmak amacı ile yapılmıştır.Gereç ve Yöntem: Çalışmaya ……… Üniversitesi
Tıp Fakültesi Parazitoloji Laboratuvarı’na Gastroenteroloji polikliniğinden
Ocak 2013 - Haziran 2013 tarihleri arasında rutin dışkı incelemesi için
gönderilen ve 1 ay içerisinde düzenli olarak PPI kullanımı olan 100 hasta ile,
hiç PPI kullanımı olmayan; fakat gastrointestinal şikayetleri olan 100 hasta
dahil edilmiştir.  Kontrol grubunu ise hiç
polikliniğe başvurmamış 100 sağlıklı birey oluşturmuştur. Dışkı örnekleri
bekletilmeden nativ-lugal yöntemi ile incelenmiştir. Bulgular: Çalışmamızda PPI kullananların %24’ünde, kullanmayanların
%5’inde ve kontrol grubunun %8’inde Blastocystis sp. saptanmıştır. Proton
pompa inhibitörlerini kullanan grupta Blastocystis sp. görülme sıklığı
anlamlı düzeyde daha yüksek bulunmuştur (X2=8,883, p<0.001).

Sonuç: Çalışma bulgularımıza dayanarak PPI kullananlarda blastosistosis’
in göz ardı edilmemesi gerektiği kanaatine varılmıştır. Mevcut literatüre göre yapmış
olduğumuz bu çalışma; Blastocystis sp.’nin görülme sıklığı ile PPI
kullanımı arasındaki ilişkiyi inceleyen ilk çalışma olup, gelecekte yapılacak
benzeri çalışmalara referans oluşturması bakımından önem arz etmektedir.
Endometrial Örnekleme Yapılan Hastaların Sonografik Bulgularının ve Histopatolojik Sonuçlarının Değerlendirilmesi
Authors: ÖZBİLGEÇ Sıtkı , ELLİBEŞ KAYA Aşkı , BAŞBUĞ Alper
Published: March 2018

Amaç: Bu çalışmanın amacı, endometrial örnekleme yapılan olgularda histopatolojik sonuçlarve sonografik veriler arasındaki ilişkinin araştırılmasıdır.Gereç ve Yöntem: Düzce Üniversitesi Tıp Fakültesi Hastanesi’nde Ocak 2015 - Ocak 2017yılları arasında endometrial örnekleme yapılan hastaların sonuçları retrospektif olarak hastaneotomasyon sisteminden ve hasta dosyalarından incelenerek değerlendirildi. Hastalarmenopozal durumlarına göre premenopoz ve postmenopoz olarak sınıflandırılarak, hastagruplarındaki sonuçlar istatistiksel olarak karşılaştırıldı.Bulgular: Hastaların 231’i premenopozal, 202’si postmenopozal dönemde idi. Premenopozalhastaların ortalama endometrial kalınlıkları 10,42 ± 6,75 (mm, mean±SD) iken,postmenopozal hastaların endometrial kalınlık ortalamaları 10,01 ± 7,26 (mm, mean±SD)bulundu. Premalign lezyonların görülme oranı, her iki grupta benzer bulundu (p=0,87,p=0,54). Postmenopozal 10 hastada malignite tanısı konuldu, bu hastaların tümünün ilkbaşvuru şikayeti postmenopozal kanamaydı. Yapılan ROC analiz ile malignite içinendometrial kalınlık sınır değeri; 8,5 mm olarak bulundu. Premenopozal dönemde,endometrial polip % 22,1 (n=51) oranında izlenirken, postmenopozal dönemde %16,3 (n=33)oranında izlendi (p=0,014). Tamoksifen kullanan 8 hastanın patoloji sonucu %75 (n=6)benign, %12,5 (n=1) premalign, %12,5 (n=1) malign olarak raporlandı.Sonuç: Postmenopozal kanamalı hastalarda endometrial örnekleme malignite ekartasyonuaçısından hayatidir
Palyatif Bakım Hastalarında Klinik Özellikler ve Prognostik Faktörler
Authors: Yürüyen Mehmet , Özbaş Tevetoğlu Işıl , Tekmen Yeliz , Polat Özlem , Arslan İsmail , Okuturlar Yıldız
Published: March 2018

Amaç: Bir palyatif bakım merkezinde yatan hastaların klinik özelliklerini
incelemek ve uzun yatış süresi, hastaneden taburculuk durumu ile ilişkili
faktörleri araştırmaktır.

Gereç ve Yöntem: Kesitsel ve retrospektif bir çalışmadır. Palyatif bakım merkezinde
1 Ağustos 2015 – 30 Temmuz 2017 tarihleri arasında yatan hastaların dosyaları
incelendi. Tüm hastaların demografik özellikleri, komorbid durumları, ilaç
sayıları, yatış şikayetleri, ilk yatışındaki nutrisyon, bası yarası ve ağrı
durumları değerlendirildi. Hastaların uzun yatış süresi (≥ 15 gün) ve
taburculuk durumları (eve taburcu, ileri yoğun bakım merkezine sevk ve eks) ile
ilişkili faktörler için değişkenler Spearman’s correlation test ile analiz
edildi.

Bulgular: Çalışmaya uygun alınan 319 hastanın (kadın, %45) ortalama yaşı
71±15,8 ve ortalama yatış süresi 15,4±15,7 gündü. En sık üç komorbid hastalık
malnütrisyon %59, malignite %44, enfeksiyon hastalığı %33 idi. En sık yatış
şikayetleri oral alım bozukluğu %35, genel durum bozukluğu %19, ateş %17 idi.

Uzun yatış süresi ile ilişkili pozitif faktörler ileri evre bası
yarası (r=0,366; p<0,001), serebrovasküler hastalık (r=0,175; p=0,002), hipertansiyon
(r=0,158; p=0,005) ve diabetes mellitusdur (r=0,129; p=0,021). Taburculuk
durumu (ileri yoğun bakıma sevk ve/veya eks durumu) ile ilişkili pozitif
faktörler ise, malignite (r=0,234; p<0,001), opioid kullanımı (r=0,204;
p<0,001), parenteral beslenme tipi (r=0,20; p<0,001) ve halsizlik-yorgunluk
semptomudur (r=0,115; p=0,041).

Sonuç: İleri evre bası yarası hastanede yatış süresini uzatan en önemli
faktördür. Hastaların taburculuk durumu için en etkili faktörler ise malignite,
opioid kullanımı, parenteral beslenme tipi ve halsizlik-yorgunluk semptomunun
varlığıdır.
Akne Vulgarisli Hastalarda İzotretinoin Tedavisinin Uyku ve Yaşam Kalitesine Etkisi
Authors: Özlü Emin , Ertaş Ragıp , Özyurt Kemal , KARAATLI İsmail , KARADAĞ Ayşe Serap
Published: March 2018

Objective: We
aimed to investigate the effect of isotretinoin treatment on sleep and quality
of life in patients with AV.

Methods: Sixty-six
AV patients, who had attended the dermatology outpatient clinic and started
isotretinoin treatment, and forty-three healthy controls, were enrolled in the
study. Pittsburg Sleep Quality Index (PSQI), short form-36 (SF-36), and Global
Acne Grading System (GAGS) were administered to all patients twice; before and
two months after the treatment. The results were compared with the healthy
control group.

Results: The
pretreatment physical health scores of the patients were significantly higher
than the healthy controls. No
significant differences were observed between before-after isotretinoin
treatment regarding physical and mental health scores in AV patients. While
there were no significant differences between the pretreatment and healthy
control group in terms of total PSQI scores; the scores of sleep duration were
significantly lower in the pretreatment group. No significant differences were
observed between before-after isotretinoin treatment regarding total PSQI and subcomponent
scores in AV patients. There was a statistically significant negative
correlation between pre- and post-treatment total PSQI scores and physical,
mental health scores in patients with AV.

Conclusion:
Results of the present study suggest that
isotretinoin therapy does not affect the sleep quality in patients with AV. The
impairment of sleep quality negatively affects the quality of life in patients
with AV. More comprehensive studies assessing the effect of isotretinoin
treatment on sleep quality are needed.
A Social Welfare Economics Proposal Through Bargaining Theory: a Win-Win-Win Papakonstantinidis Model Approach Inserting Overall Arbitrator Player to the Local Development Game
Authors: Papakonstantinidis Leonidas , Barbarousi Christina
Published: March 2018

In this study, we investigate the impact of Social Bargain on Welfare Problem adopting the win-win-win Papakonstantinidis model inserting the Overall Arbitrator Player into the local development game. This deals with (a) the failure of Public Choice in the production of social welfare, (b) the Bargaining Process as a proposal for generating social capital in the field of Welfare Economics. The purpose of this research is to indicate that Public Choice fails to lead to Economic Development. Instead, this can be achieved by implementing Social Bargaining Process into the game of social welfare. In particular, the gap between development and underdevelopment (regional problem) in the community is being investigated, while it is identified as being real and unresolved in the literature of Social Choice Theory and Regional Science. This gap can be corrected – cured through Social Bargaining Process as a solution to the Welfare Problem. The above is being interpreted as follows: the agents of the game or voters of the community can make such collective decisions that eliminate regional disparities by choosing strategies or politicians that will make the appropriate assessments/choices for the community. The key questions are: a) why Public Choice fails to solve the problem of regional disparities and to lead to social welfare, (b) what makes the Social Bargaining Process the appropriate solution to the social welfare problem (or regional problem) and above it should be dealt with. As a methodology is being proposed the Mediation Theory model among two other processes: (1) The “Principal-Agent” process, considering Principal’s position as strong, and (2) the Leadership of a community and a single Member of the same community (“Leader-Member Exchange” – LMX), considering the Leader’s position as strong. The research findings proposed the creation of a social player in the bargaining process, where introduces the generation of social capital, that leads to social welfare to which Public Choice fails to lead and this point is also the originality of the paper.
МОТИВАЦИЈА СТУДЕНАТА ХЕМИЈЕ ЗА ИЗУЧАВАЊЕ ХЕМИЈСКИХ НАСТАВНИХ САДРЖАЈА
Authors: Олић Станислава , Адамов Јасна , Бабић Кекез Снежана
Published: March 2018

Циљ рада је да се испита мотивација студената за учење хемијских наставних садржаја као и да се испитају разлике у мотивацији студената различитих година студија и студијског програма. Укупно 185 студената прве и четврте године хемије попунило је упитник за процену мотивације за учење хемије која се састоји из пет супскала: самоефикасност, примена стратегија активног учења, схватање значаја хемије као науке, мотивациона оријентација на учење и оријентација на постигнуће. Добијени резултати су показали да су студенти хемије генерално мотивисани за изучавање хемијских садржаја. Студенти завршних година су показали већу мотивисаност за учење у односу на студенте прве године а разлике се пре свега односе на њихово осећање самоефикасности. С друге стране, стратегије активног учења у већој мери примењују студенти прве године. Разлике у мотивацији између студената различитих група се нису показале значајним изузев у примени стратегија активног учења.
Outflow Enhancement by Three Different ab Interno Trabeculectomy Procedures in a Porcine Anterior Segment Model
Authors: Dang Yalong , Wang Chao , Shah Priyal , Waxman Susannah , Loewen Ralitsa T. , Hong Ying , Esfandiari Hamed , Loewen Nils A.
Published: March 2018

Purpose: To evaluate three different microincisional ab interno trabeculectomy procedures in a porcine eye perfusion model. Methods: In perfused porcine anterior segments, 90 degrees of trabecular meshwork (TM) were ablated using the Trabectome (T; n = 8), Goniotome (G; n = 8), or Kahook device (K; n = 8). After 24 hours, additional 90 degrees of TM were removed. Intraocular pressure (IOP) and outflow facility were measured at 5 µL/min and 10 µL/min perfusion to simulate an elevated IOP. Structure and function were assessed with canalograms and histology. Results: At 5 µL/min infusion rate, T resulted in a greater IOP reduction than G or K from baseline (76.12% decrease versus 48.19% and 47.96%, P = 0.013). IOP reduction between G and K was similar (P = 0.420). Removing another 90 degrees of TM caused an additional IOP reduction only in T and G but not in K. Similarly, T resulted in the largest increase in outflow facility at 5 µL/min compared with G and K (first ablation: 3.41 times increase versus 1.95 and 1.87; second ablation: 4.60 versus 2.50 and 1.74) with similar results at 10 µL/min (first ablation: 3.28 versus 2.29 and 1.90 (P = 0.001); second ablation: 4.10 versus 3.01 and 2.01 (P = 0.001)). Canalograms indicated circumferential flow beyond the ablation endpoints. Conclusions: T, G and K significantly increased the outflow facility. In this model, T had a larger effect than G and K.
Genetic Optimization Algorithm for Metabolic Engineering Revisited
Authors: Alter Tobias B. , Blank Lars M. , Ebert Birgitta E.
Published: March 2018

To date, several independent methods and algorithms exist exploiting constraint-based stoichiometric models to find metabolic engineering strategies that optimize microbial production performance. Optimization procedures based on metaheuristics facilitate a straightforward adaption and expansion of engineering objectives as well as fitness functions, while being particularly suited for solving problems of high complexity. With the increasing interest in multi-scale models and a need for solving advanced engineering problems, we strive to advance genetic algorithms, which stand out due to their intuitive optimization principles and proven usefulness in this field of research. A drawback of genetic algorithms is that premature convergence to sub-optimal solutions easily occurs if the optimization parameters are not adapted to the specific problem. Here, we conducted comprehensive parameter sensitivity analyses to study their impact on finding optimal strain designs. We further demonstrate the capability of genetic algorithms to simultaneously handle (i) multiple, non-linear engineering objectives, (ii) the identification of gene target-sets according to logical gene-protein-reaction associations, (iii) minimization of the number of network perturbations, and (iv) the insertion of non-native reactions, while employing genome-scale metabolic models. This framework adds a level of sophistication in terms of strain design robustness, which is exemplarily tested on succinate overproduction in Escherichia coli.
Microstructure and Properties of 2219 Aluminum Alloy under Compound Technologies of Friction-Stir-Welding, Heat-Treatment and Electromagnetic Forming
Authors: Wang Zeyu , Huang Liang , Li Jianjun , Li Xiaoxia , Zhu Hui , Ma Fei , Ma Huijuan , Cui Junjia
Published: March 2018

Among all the processing technologies of heat-treatable aluminum alloys like 2219 aluminum alloy, using friction stir welding (FSW) as the joining technology and using electromagnetic forming (EMF) for plastic forming technology both have obvious advantages and successful applications. Therefore, there is a broad prospect for the compound technologies which can be used on the 2219 aluminum alloy to manufacture the large-scale thin-wall parts in the astronautic industry. The microstructure and mechanical properties of 2219 aluminum alloy under the process compounded of FSW, heat treatment, and EMF were investigated by means of tensile test, optical microscope (OM), and scanning electron microscope (SEM). The results show that the reduction of strength, which was caused during the FSW process, can be recovered effectively by the post-welding heat treatment composed of solid solution and aging, while the ductility was still reduced after heat treatment. Under the compound technology of FSW, heat treatment, and EMF, the forming limit of 2219 aluminum alloy decreased distinctly due to the poor ductility of the welding joint. A ribbon-pattern, which was formed due to the banded structure caused by FSW process, was found on the fracture surface of welded 2219 aluminum alloy after EMF treatment. During the EMF process, because of the effects of induced eddy current, a unique structure, which was manifested as a molted-surface appearance under the SEM observation, was formed as the material fractured.
Recent Advances in Next Generation Snakebite Antivenoms
Authors: Knudsen Cecilie , Laustsen Andreas Hougaard
Published: March 2018

With the inclusion of snakebite envenoming on the World Health Organisation’s list of Neglected Tropical Diseases, an incentive has been established to promote research and development effort in novel snakebite antivenom therapies. Different technological approaches are being pursued by different research groups, including the use of small molecule inhibitors against enzymatic toxins, as well as peptide and oligonucleotide-based aptamers and antibody-based biotherapeutics against both enzymatic and non-enzymatic toxins. In this article, the most recent advances in these fields are presented, and the advantages, disadvantages, and feasibility of using different toxin-neutralizing molecules are reviewed. Particular focus within small molecules is directed towards the inhibitors, varespladib, batimastat, and marimastat, while in the field of antibody-based therapies, novel recombinant polyclonal plantivenom technology is discussed.
NC-Cross Entropy Based MADM under Neutrosophic Cubic Set Environment
Authors: Pramanik Surapati , Dalapati Shyamal , Alam Shariful , Smarandache Florentin , Roy Tapan Kumar
Published: March 2018

Neutrosophic cubic set (NCS) is one of the important family members of neutrosophic hybrid sets. Neutrosophic cubic set has more strength than other family members of neutrosophic hybrid sets to express incomplete information due to the presence of interval valued neutrosophic set (IVNS) and single valued neutrosophic set (SVNS) in its structure. Cross entropy measure is one of the best way to calculate the divergence of any variable from the priori one variable. In this paper we first define a new cross entropy measure under NCSs environment which we call NC- cross entropy measure. We investigate the basic properties of NC-cross entropy. We also propose weighted NC-cross entropy and investigate its basic properties. We develop a novel multi attribute decision making (MADM) strategy based on weighted NC-cross entropy. To show the feasibility and applicability, we solve a MADM problem using the proposed strategy.
Hybrid Logarithm Similarity Measure Based MAGDM Strategy under SVNS Environment
Authors: Mondal Kalayn , Pramanik Surapati , Giri Bibhas C. , Smarandache Florentin , Ye Jun
Published: March 2018

The objective of the paper is to introduce new similarity measure for single valued neutrosophic sets based on logarithm function. We define logarithm similarity measure and their weighted similarity measure for single valued neutrosophic sets. Then we define hybrid logarithm similarity measure and weighted hybrid logarithm similarity measure for single valued neutrosophic sets. We prove the basic properties of the proposed measures. We then define an entropy function using logarithm function to determine unknown attribute weights. We develop a novel multi attribute group decision making strategy for single valued neutrosophic sets based on the weighted hybrid logarithm similarity measure. We address an illustrative example to demonstrate the effectiveness and aptness of the proposed strategies. We conduct a sensitivity analysis of the developed strategy. We also make a comparison between the obtained results from proposed strategies and different existing strategies in the literature.
Cadastre-Land Registry Coordination in Spain: Application of Law 13/2015 and Its Effects
Authors: Femenia-Ribera Carmen , Mora-Navarro Gaspar
Published: March 2018

Ever since the Cadastre and Land Registry have existed in Spain, they have been completely separate organisations with very different objectives, which influence the real-estate reality. Their coordination is essential to better identify buildings and to more suitably render services to citizens and Administrations. To this end, Law 13/2015 was passed in 2015 for this desirable and pressing Cadastre-Land Registry coordination to come about. This law came into force on 1 November 2015, and coincided with the development of the technical aspects of the graphical information exchange among the Cadastre, Land Registries and Notaries. Several ministries and different organisations, like the Cadastre personnel, jurists, technicians, and even citizens, are implied in this law. Among the technical aspects, georeferenced graphical representations and GML exchange files adapted to the European INSPIRE directives stand out. Such technical aspects are a genuine revolution as they were transferred to the legal world. After more than 2 years after its application, it is still in its initial and adaptation stages because it is a long-standing law that allows land registry units-cadastral parcels to be coordinated while they are incorporated into real-estate trade.
Evaluation of Climate Change Impacts on Wetland Vegetation in Dunhuang Yangguan National Nature Reserve in Northwest China Using Landsat Derived NDVI
Authors: Pan Feifei , Xie Jianping , Lin Juming , Zhao Tingwei , Ji Yongyuan , Hu Qi , Pan Xuebiao , Wang Cheng , Xi Xiaohuan
Published: March 2018

Based on 541 Landsat images between 1988 and 2016, the normalized difference vegetation indices (NDVIs) of the wetland vegetation at Xitugou (XTG) and Wowachi (WWC) inside the Dunhuang Yangguan National Nature Reserve (YNNR) in northwest China were calculated for assessing impacts of climate change on wetland vegetation in the YNNR. It was found that the wetland vegetation at the XTG and WWC both had shown a significant increasing trend in the past 30 years, and the increase in both annual mean temperature and peak snow depth over the Altun Mountains led to the increase of wetland vegetation. The influence of local precipitation on the XTG wetland vegetation was greater than on the WWC wetland vegetation, which demonstrates that in extremely arid regions, the major constrain to the wetland vegetation is water availability in soils which is greatly related to the surface water detention and discharge of groundwater. At both XTG and WWC, snowmelt from the Altun Mountains is the main contributor to the groundwater discharge, while local precipitation plays a less role in influencing the wetland vegetation at the WWC than at the XTG, because the wetland vegetation grows on a relatively flat terrain at the WWC, while in a stream channel at the XTG.
Recombinant TMV Vector for Production of Highly Immunogenic Plant-Based Vaccine Antigens Against Herpes Simplex Virus Type 2
Authors: El-Attar Ahmad , Aboul-Ata Aboul-Ata , Persson Josefine , Mazyad Hamed , Harandi Ali M. , Olsson Olof
Published: March 2018

A B S T R A C T Genital herpes disease is caused mainly by herpes simplex virus type 2 (HSV-2), which is sexually transmitted with a high prevalence in both developed and developing countries. No vaccine is currently available against genital herpes. In this study, we introduced and expressed two genes encoding HSV-2 glycoprotein D (gD) and VP16 protein and a GFP marker gene (control) in tobacco seedlings. Positive plant infection was assessed through characteristic tobacco mosaic virus disease symptoms on leaves and by monitoring the fluorescence emitted by the expressed GFP protein. Expression of the HSV-gD2 and VP16 antigens was verified by RT-PCR, ELISA and Western blot. As a proof of concept, the immunogenicity and the protection ability of the plant produced gD antigen was tested in a mouse model of genital herpes and compared to gD antigen produced in a mammalian expression system. This showed that the plant-gD preparation, when used in combination with a CpG oligodeoxynucleotide as adjuvant, was highly immunogenic and capable of inducing complete immunity to lethal vaginal HSV-2 challenge in mice. Thus, the data presented here may have implications for the development of a production system for highly immunogenic plant-based HSV-2 vaccine antigens.
Adab as Social Currency: the Survival of the Qaṣīda in Medieval Sicily
Authors: CARPENTIERI Nicola
Published: March 2018

This article explores the resilience of the qaṣīda as social currency in the Kalbid and Norman periods of Sicily. It demonstrates how the Kalbid emirs incorporated the sociopoietic function of the Arabic ode — its capacity to create bonds of social exchange based on a shared ethos — in their programme to foster cohesion at a court potentially endangered by social, confessional and ethnic rivalries. It subsequently shows how the qaṣīda carried out a comparable function at the Norman court of Roger II, where Arabic poets once again resorted to the language and lore of the qaṣīda in order to craft a neutral space of interaction for Muslims and Christians at court.
Aristotelian Theories in Abraham ibn Ezra's Commentaries to the Bible
Authors: GÓMEZ ARANDA Mariano
Published: March 2018

Some of Abraham ibn Ezra’s philosophical ideas exposed in his biblical commentaries are the same as those of Aristotle. The purpose of this article is to analyse some of the Aristotelian ideas appearing in Abraham ibn Ezra’s biblical commentaries and explain how he adapts the Aristotelian concepts to the explanation of the specific biblical verses. Ibn Ezra uses these concepts in his explanation of the structure of the Universe as found in some Psalms, the creation of the world in Genesis 1, and the origin of evil according to the book of Ecclesiastes. This paper also attempts to provide a hypothesis on how Ibn Ezra was able to apprehend Aristotelian philosophy.
Mauro Zonta and the Unity of Medieval Philosophy
Authors: MARENBON John
Published: March 2018

In memoriam
Jacopo Aconcio. Breve biografia di un ‘eretico minore’ del Cinquecento
Authors: TRAVERSINO DI CRISTO Massimiliano
Published: March 2018

This paper presents the life of the Italian-born and English-naturalized sixteenth-century 'minor heretic' Jacopo Aconcio. Best known for his pioneering contribution on toleration in the early stage of Reformation, Aconcio's interests were split between law, philosophy, theology, and engineering.
Between Istanbul and Venice: Agency, Faith, and Empire in the Sixteenth Century
Authors: MARTIN John Jeffries
Published: March 2018

Noel Malcolm’s Agents of Empire: Knights, Corsairs, Jesuits and Spies in the Sixteenth-Century Mediterranean World brilliantly excavates and reconstructs the lives of the members of the Bruni and the Bruti, two prominent Albanian families, whose members played significant roles in the political and military history of the Ottoman and Venetian Empires. This review essay attempts to place this important work in the broader context of Malcolm’s oeuvre and, in particular, to assess the book’s contributions to our understanding of agency, religion, and empire in the early modern period.
Zachary A. Matus, Franciscans and the Elixir of Life: Religion and Science in the Later Middle Ages, Philadelphia: University of Pennsylvania Press, 2017, 203 pp., ISBN 9780812249217 (Pbk) – 9780812294064 (Ebk)
Authors: RINOTAS Athanasios
Published: March 2018

Review: Zachary A. Matus, Franciscans and the Elixir of Life: Religion and Science in the Later Middle Ages, Philadelphia: University of Pennsylvania Press, 2017, 203 pp., ISBN 9780812249217 (Pbk) – 9780812294064 (Ebk)
Raimundi Lulli Opera Latina 44: Ars inventiva veritatis, ed. Jorge Uscatescu Barrón, Turnhout: Brepols, 2014 (Corpus Christianorum. Continuatio Mediaevalis, 265; Raimundi Lulli Opera Latina, 37), CXXII + 513 pp., ISBN 9782503552569
Authors: COLOMBA Coralba
Published: March 2018

Review: Raimundi Lulli Opera Latina 44: Ars inventiva veritatis, ed. Jorge Uscatescu Barrón, Turnhout: Brepols, 2014 (Corpus Christianorum. Continuatio Mediaevalis, 265; Raimundi Lulli Opera Latina, 37), CXXII + 513 pp., ISBN 9782503552569
Responding to English Grammatical Challenges: The Design and Development of Exemplary Material for Form One Learners in Tanzania
Authors: William Fancis , Hamaro Gilbrita John
Published: March 2018

This article proposes strategies for designing and evaluating curriculum materials for enhancing English language grammatical competence among Form One learners in Tanzanian secondary schools. Using quasi-experimental and phenomenological designs, the authors developed an exemplary Learner Centered Instructional Grammar Material (LCIGM) focusing on Form One learners. Materials design approach and Constructivism Theory of learning guided the exercise. The data for the study were collected through documentary review, interviews, questionnaires and teaching and learning observations of 40 Form One learners chosen from three randomly selected secondary schools in the Dodoma Region of Tanzania. Both pre-test and post-tests were done to understand the suitability of the newly developed material to meet the purpose of enhancing grammatical competence among Form One learners. The findings and observations revealed that both teachers and learners benefited from the designed activity-based material which, in turn, enhanced learners’ grammatical performance, both in spoken and written form. The authors concluded by urging the stakeholders to design the material that are activity based to improve the learners’ grammatical competence.
Mentor teachers’ feedback role in improving the training of Grades 1-3 student teachers in South Africa
Authors: Hugo Anna Johanna
Published: March 2018

Mentor teachers play a vital role in the pre-service training of teachers.  The role of mentor teachers assumes even more significance when the training is done at a distance education institution.  It is impossible for lecturers and university representatives to reach every teacher student during the weeks of teaching practice done at schools in a big country like South Africa.  The feedback obtained from the mentor teachers is thus important to train student teachers when they present their lessons during weeks of teaching practice at schools.  But the feedback from mentor teachers can also be used for the future training of student teachers.  Mentor teachers should, however, also be informed about their role as mentors for student teachers.  In this article the way feedback of mentor teachers could be used to improve the quality of the lessons of student teachers when offering language lessons in Grades 1 – 3, is discussed.
Stężenie chromu w materiale kostnym człowieka a czynniki biologiczne i środowiskowe
Authors: Łanocha-Arendarczyk Natalia , Kalisińska Elżbieta , Kaplewska Małgorzata Anna , Budis Halina , Sokołowski Sebastian , Kot Karolina , Kosik-Bogacka Danuta
Published: March 2018

ABSTRAKTWstęp: Celem pracy było poznanie i porównanie stężenia chromu (Cr) w trzech rodzajach materiału kostnego: chrząstce, kości zbitej i kości gąbczastej, pobranego z głowy kości udowej. Ponadto oceniono wpływ czynników ogólnobiologicznych i środowiskowych na stężenie Cr w badanych próbkach.Materiały i metody: Z głowy kości udowej pobranej od pacjentów (n = 37) poddanych alloplastyce stawu biodrowego odseparowano chrząstkę, kość zbitą i gąbczastą, które wysuszono do stałej masy, zmineralizowano w stężonych kwasach i w których oznaczono stężenie Cr metodą spektrofotometrii absorpcji atomowej (ICP-AES).Wyniki: Stężenie Cr w analizowanych próbkach kostnych można ułożyć w następujący malejący szereg: chrząstka < kość zbita < kość gąbczasta. Nie odnotowano zależności pomiędzy wiekiem i płcią badanych pacjentów a stężeniem Cr w próbkach kostnych. U osób pracujących w przemyśle ciężkim wartość stężenia Cr była prawie 30% większa niż u pracowników innych działów gospodarki. Wykazano zależność pomiędzy liczbą wypalanych papierosów (<10 lub ≥20) a stężeniem Cr w kości zbitej. Osoby wypalające ≥20 papierosów dziennie miały znacznie większe stężenia Cr w badanym materiale niż osoby wypalające <10 papierosów dziennie. Nie zaobserwowano istotnych różnic pomiędzy spożyciem dziczyzny, ryb i owoców morza a stężeniem Cr w analizowanych próbkach.Wnioski: Wiele wskazuje na to, że wielkości stężenia chromu w kościach pacjentów poddanych alloplastyce stawu biodrowego mogą być powiązane z czynnikami ogólnobiologicznymi i środowiskowymi, ale niezbędne są szersze i liczniejsze badania w tym zakresie, także w innych krajach Europy Środkowej.
Nanomaterials in dentistry – potential capabilities, applications, limitations and hazards. Review of the literature. Part 2
Authors: Dalewski Bartosz , Sobolewska Ewa , Frączak Bogumiła
Published: March 2018

ABSTRAKTWstęp: Nanotechnologia na dobre zagościła w poszczególnych specjalizacjach stomatologicznych jako nowatorska metodologicznie idea wdrażania materiałów o zarówno podwyższonych parametrach mechanicznych, jak i posiadających olbrzymi potencjał antymikrobiologiczny. Praca przedstawia obecny postęp, perspektywy, potencjalne przyszłe zastosowania oraz ograniczenia nanocząstek w aspekcie wytrzymałości określonych materiałów stomatologicznych oraz ich odporności na biofilm jamy ustnej.Celem niniejszego przeglądu piśmiennictwa była rzetelna analiza potencjalnych korzyści i zagrożeń wynikających z zastosowania nanocząsteczek w jamie ustnej w świetle medycyny opartej na dowodach, zarówno obecnie, jak i w niedalekiej przyszłości.Metody: Przeszukano bazy danych Medline (PubMed) i ISI Web of Science.Wyniki: Nanomateriały posiadają znaczący potencjał hamujący agregację płytki bakteryjnej, mogą przeciwdziałać procesom demineralizacji, remineralizować tkanki zębów oraz zwalczać określone typy drobnoustrojów. Jednakże ich zdolność do znoszenia dodatkowych obciążeń, a tym samym zwiększania wytrzymałości mechanicznej, nie znajduje potwierdzenia w obecnie dostępnym piśmiennictwie i wymaga dalszych badań. Również odległe skutki ich użycia, z potencjalną toksycznością włącznie, nakazują zachować dalece idącą ostrożność w stosowaniu.
Organiczne zaburzenia urojeniowe u pacjentki po przeszczepie nerki – opis przypadku
Authors: Bąba-Kubiś Agata , Pełka-Wysiecka Justyna , Liśkiewicz Paweł , Wroński Michał , Samochowiec Jerzy
Published: March 2018

ABSTRAKTWstęp: W niniejszym artykule przedstawiono przypadek pacjentki chorującej na organiczne zaburzenia urojeniowe. Początek objawów psychiatrycznych następował stopniowo w okresie kilku tygodni po przeszczepieniu pacjentce nerki od zmarłego dawcy.Opis przypadku: 42-letnia pacjentka została przyjęta na oddział psychiatrii w celu obserwacji stanu psychicznego oraz ewentualnej modyfikacji postawionego wcześniej rozpoznania klinicznego.Komentarz: Objawy psychotyczne o charakterze urojeń ksobnych, prześladowczych oraz omamów słuchowych pojawiły się u pacjentki w okresie kilku tygodni po przeszczepie nerki od zmarłego dawcy. Objawy te miały tendencję do stopniowego nasilania się. Zgodnie ze standardami postępowania potransplantacyjnego pacjentka przyjmowała zwiększone dawki leków immunosupresyjnych, jednak mimo redukcji dawek objawy psychotyczne nie uległy zmniejszeniu. Pacjentka obciążona była somatycznie chorobą Hashimoto, nadciśnieniem tętniczym, wirusowym zapaleniem wątroby typu B, zakrzepicą tętnicy szyjnej wewnętrznej, cukrzycą typu 2 powikłaną nefropatią, retinopatią i neuropatią.Wnioski: Przedstawiony przypadek stanowi przykład wielo­czynnikowej etiologii objawów psychopatologicznych oraz wskazuje na konieczność uwzględniania wielu aspektów stanu somatycznego przy ustalaniu diagnozy psychiatrycznej i planowaniu leczenia pacjenta.
Martwicze zapalenie tkanek miękkich krocza imitujące ropień okołoodbytowy – opis przypadku
Authors: Żyluk Andrzej , Jagielski Wojciech , Szlosser Zbigniew
Published: March 2018

ABSTRAKTOpisano przypadek martwiczego zapalenia tkanek miękkich okołoodbytowych imitującego ropień okołoodbytowy, którego rozległość i przebieg kliniczny mogły odpowiadać łagodnej formie zgorzeli Fourniera. U nieobciążonej dodatkowymi chorobami 65-letniej pacjentki choroba rozwinęła się w ciągu 5 dni, powodując martwicę okołoodbytowych tkanek miękkich i uogólnione zakażenie. Miejscowy wygląd zmian przypominał ropień umiejscowiony po obu stronach odbytu. Leczenie operacyjne przez rozległe nacięcie zmienionej zapalnie okolicy, ewakuację tkanek martwiczych i antybiotykoterapię było skuteczne, ale musiało być powtarzane, a zamknięcie ubytku skóry na pośladku w okolicy odbytu wymagało plastyki płatowej.
Stomatologiczna opieka zdrowotna nad dziećmi w Zielonej Górze w latach 1950–1989
Authors: Kotuła Jacek , Kierzek Andrzej
Published: March 2018

ABSTRAKTZainteresowanie stomatologią dziecięcą sięga początku XX w. W USA Georg Eastman jako pierwszy zaproponował umieszczenie gabinetu stomatologicznego dla dzieci w szkole. Pomimo fiaska projektu związanego z brakami finansowymi znalazł on naśladowców. Jednym z nich był Ernst Jessen, który w Strasburgu utworzył pierwszą w Europie bezpłatną przychodnię stomatologiczną dla dzieci. W Polsce w 1912 r. z inicjatywy docenta Tomasza Janiszewskiego w Krakowie powstały pierwsze ambulatoria dentystyczne dla ubogich dzieci. W 1916 r. została wydrukowana przez Miejskie Ambulatorium Dentystyczne w Krakowie broszura dla ubogich dzieci, w której zwrócono uwagę m.in. na konieczność profilaktyki próchnicy i leczenia zębów w związku z ich kardynalnym znaczeniem dla ogólnego stanu zdrowia człowieka.Organizacja systemu opieki zdrowotnej w okresie powojennym na terenie Zielonej Góry wiązała się z implementacją do polskich warunków modyfikacji siemaszkowskiego modelu opieki zdrowotnej opartego na powszechnym i bezpłatnym dostępie do świadczeń opieki zdrowotnej całego społeczeństwa.Wprowadzenie bezpłatnej stomatologicznej opieki zdrowotnej nad dziećmi wiązało się z funkcjonowaniem szkolnych i międzyszkolnych poradni stomatologicznych. Stomatologia dziecięca wiązała się z prowadzeniem leczenia planowego, profilaktyki fluorkowej i promocji zdrowia w poradniach zlokalizowanych w szkołach i przedszkolach.Pedodoncja była wspomagana przez rozwijające się poradnie ortodontyczne. Prowadziły one profilaktykę ortodontyczną w przedszkolach oraz leczenie aparatami ruchomymi w poradniach miejskich, obwodowych i wojewódzkich.Rozwój stomatologicznej opieki zdrowotnej nad dziećmi odbywał się w warunkach ogromnego, niezaspokojonego zapotrzebowania społecznego na pomoc dentystyczną, dużego deficytu lekarzy stomatologów oraz stale powiększającego się zakresu świadczeń stomatologicznych. Brak odpowiedniego finansowania wpływał na trudne warunki pracy lekarzy dentystów i brak możliwości zaspokojenia potrzeb mieszkańców miasta. Stomatologiczna opieka zdrowotna wpisywała się w trójstopniowy podział referencyjności placówek medycznych.
A Novel Coreless Injectivity Technique for Evaluating Formation Damage in Argillaceous Reservoirs
Authors: Luo Peng , Knorr Kelvin D. , Nakutnyy Petro , Crabtree Mike
Published: March 2018

For waterflooding in argillaceous reservoirs, the injection water needs to be carefully designed to avoid formation damage by clay swelling and migration. Common methods of achieving this are compatibility tests of injection water with formation water and rocks and injectivity tests. However, such tests are often not practical nor even possible due to the limited availability and prohibitive cost of obtaining actual reservoir cores. The objective of this work was to develop a cost-effective method to evaluate injectivity that does not require the use of reservoir core. In this study, a novel coreless injectivity method was developed and validated. The method utilizes field-produced drill cuttings to make synthetic core plugs, which are universally available during well drilling and commonly considered as waste. A specially designed cleaning process was performed for the drill cuttings. They were then wet compressed with a high-pressure hydraulic press and dried in a constant-humidity oven to make core plugs with standard dimensions. Drill cutting plugs prepared in this way can then be used for injectivity tests as an alternative to actual reservoir core plugs. The routine core analysis revealed that, although sedimentary structures were lost, the drill cutting plugs preserved the mineralogy and maintained comparable porosity and permeability to the reservoir plugs. To validate the representativeness of the formation damage tendencies of the drill cutting plugs, water injectivity tests were carried out on both preserved reservoir cores and compressed drill cutting cores, using simulated injection water with successively lower salinities. The results showed that injectivity loss as indicated by increasing pressure drop was consistent with both types of cores. The "coreless injectivity evaluation" technique can be applied for argillaceous reservoirs with formation damage concerns. It is a cost-effective and viable technique for evaluating water injectivity when reservoir cores are unavailable.
Structure-Property Model for Microemulsion Phase Behavior
Authors: Chang Leonard , Jang Sung Hyun , Tagavifar Mohsen , Pope Gary A.
Published: March 2018

The objective of this research was to develop a model to predict the optimum phase behavior of chemical formulations for a given oil based on the molecular structure of the surfactants and co-solvents. The model is sufficiently accurate to provide a useful guide to an experimental testing program for the development of chemical EOR formulations. There are thousands of combinations of surfactants and co-solvents that could be tested for each oil, so even approximate predictions are very useful in terms of reducing the time and effort required for testing and for prioritizing the chemical combinations to test that are most likely to yield ultra-low IFT at reservoir conditions. The effects of changing molecular structures (e.g. swapping head groups, swapping hydrophobes, increasing the length of hydrophobes, increasing the number of PO and EO groups, adjusting the ratios of surfactants) are shown. The variables with the greatest impact on the optimum salinity and solubilization ratio were identified, and methods are proposed to shift the optimum salinity and the optimum solubilization ratios in any desired direction. The structure-property model was developed and tested using a large dataset consisting of 684 microemulsion phase behavior experiments using 24 oils. The chemical formulations used 85 surfactants and 18 co-solvents in various combinations. Both optimum salinity and optimum solubilization ratio (and thus IFT) are modeled whereas other models have focused almost exclusively on the optimum salinity. Predicting the optimum solubilization ratio is actually of more value because of its relationship to IFT. The models include the effects of co-solvent partitioning, soap formation and the molecular structure of both the surfactants and co-solvents.
Comprehensive Review of Worldwide CO2 Immiscible Flooding
Authors: Zhang Na , Wei Mingzhen , Bai Baojun
Published: March 2018

Carbon dioxide (CO2) flooding is a mature technology in oil industry, which finds broad attention in oil production during tertiary oil recovery (EOR). After five decade's developments, there are many successful reports for CO2 miscible flooding. However, operators recognized that achieving miscible phase is one of big challenge in fields with extremely high minimum miscible pressure (MMP) after considering the safety and economics. Compared with CO2 miscible flooding, immiscible CO2 flooding demonstrates the great potentials under varying reservoir/fluid conditions. A comprehensive and high-quality data set for CO2 immiscible flooding are built by collecting various data from books, DOE reports, AAPG database, oil and gas biennially EOR survey, field reports and SPE publications. Important reservoir/fluid information, operational parameters and project performance evaluations are included, which provides the basis for comprehensive data analysis. Combination plot of boxplot and histogram are generated, where boxplots are used to detect the special cases and to summarize the ranges of each parameter; histograms display the distribution of each parameter and to identify the best suitable ranges for propose guidelines.

Results show that CO2 immiscible flooding could recover additional 4.7 to 12.5% of oil with average injection efficiency of 10.07 Mscf/stb; CO2 immiscible technique can be implemented in light/medium/heavy oil reservoirs with a wide range of net thickness (5.2 - 300 ft); yet in heavy oil specifically reservoir (oil gravity <25 °API) with thin layer (net thickness< 50 ft) is better.