bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of Powerlifting Performance in Trained Men Using Traditional and Flexible Daily Undulating Periodization
Authors: Colquhoun Ryan J. , Gai Christopher M. , Walters Jeoffrey , Brannon Andrew R. , Kilpatrick Marcus W. , D'Agostino Dominic P. , Campbell William I.
Published: May 2016

Colquhoun, RJ, Gai, CM, Walters, J, Brannon, AR, Kilpatrick, MW, D'Agostino, DP, and Campbell, WI. Comparison of powerlifting performance in trained men using traditional and flexible daily undulating periodization. J Strength Cond Res 31(2): 283–291, 2017—Daily undulating periodization (DUP) is a growing trend, both in practice and in the scientific literature. A new form of DUP, flexible daily undulating periodization (FDUP), allows for athletes to have some autonomy by choosing the order of their training. The purpose of this study was to compare an FDUP model to a traditional model of DUP on powerlifting performance in resistance-trained men. Twenty-five resistance-trained men were randomly assigned to one of 2 groups: FDUP (N = 14) or DUP (N = 11). All participants possessed a minimum of 6 months of resistance training experience and were required to squat, bench press, and deadlift 125, 100, and 150% of their body mass, respectively. Dependent variables assessed at baseline and after the 9-week training program included bench press 1 repetition maximum (1RM), squat 1RM, deadlift 1RM, powerlifting total, Wilks Coefficient, fat mass, and fat-free mass (FFM). Dependent variables assessed during each individual training session were motivation to train, Session Rating of Perceived Exertion (Session RPE), and satisfaction with training session. After the 9-week training program, no significant differences in intensity or volume were found between groups. Both groups significantly improved bench press 1RM (FDUP: +6.5 kg; DUP: +8.8 kg), squat 1RM (FDUP: +15.6 kg; DUP: +18.0 kg), deadlift 1RM (FDUP: +14.8 kg; DUP: +13.6 kg), powerlifting total (FDUP: +36.8 kg; DUP: +40.4 kg), and Wilks Coefficient (FDUP: +24.8; DUP: +26.0) over the course of study (p = <0.001 for each variable). There was also a significant increase in FFM (FDUP: +0.8 kg; DUP: +0.8 kg) for both groups (p = 0.003). There were no differences in motivation to train, session RPE, or satisfaction with training session measurements between groups (p = 0.369–0.702, respectively). In conclusion, FDUP seems to offer similar resistance training adaptations when compared with a traditional DUP in resistance-trained men.
Generalization of Muscle Strength Capacities as Assessed From Different Variables, Tests, and Muscle Groups
Authors: Cuk Ivan , Prebeg Goran , Sreckovic Sreten , Mirkov Dragan M. , Jaric Slobodan
Published: May 2016

Cuk, I, Prebeg, G, Sreckovic, S, Mirkov, DM, and Jaric, S. Generalization of muscle strength capacities as assessed from different variables, tests, and muscle groups. J Strength Cond Res 31(2): 305–312, 2017—The muscle strength capacities to exert force under various movement conditions have been indiscriminately assessed from various strength tests and variables applied on different muscles. We tested the hypotheses that the distinctive strength capacities would be revealed (H1) through different strength tests, and (H2) through different strength variables. Alternatively, (H3) all strength variables independent of the selected test could depict the same strength capacity of the tested muscle. Sixty subjects performed both the standard strength test and the test of alternating contractions of 6 pairs of antagonistic muscles acting in different leg and arm joints. The dependent variables obtained from each test and muscle were the maximum isometric force and the rate of force development. A confirmatory principle component analysis set to 2 factors explained 31.9% of the total variance. The factor loadings discerned between the tested arm and leg muscles, but not between the strength tests and variables. An exploratory analysis applied on the same data revealed 6 factors that explained 60.1% of the total variance. Again, the individual factors were mainly loaded by different tests and variables obtained from the same pair of antagonistic muscles. Therefore, a comprehensive assessment of the muscle strength capacity of the tested individual should be based on a single strength test and variable obtained from a number of different muscles, than on a single muscle tested through different tests and variables. The selected muscles should act in different limbs and joints, while the maximum isometric force should be the variable of choice.
Heart-Rate Variability Threshold as an Alternative for Spiro-Ergometry Testing: A Validation Study
Authors: Mankowski Robert T. , Michael Scott , Rozenberg Robert , Stokla Sebastiaan , Stam Henk J. , Praet Stephan F.E.
Published: May 2016

Mankowski, RT, Michael, S, Rozenberg, R, Stokla, S, Stam, HJ, and Praet, SFE. Heart-rate variability threshold as an alternative for spiro-ergometry testing: a validation study. J Strength Cond Res 31(2): 474–479, 2017—Although spiro-ergometry is the established “gold standard” for determination of the second ventilatory threshold (VT2), it is a costly and rather time-consuming method. Previous studies suggest that assessing the second anaerobic threshold (AT2) on the basis of heart rate variability (HRV) during exercise may be a more cost-effective and noninvasive manner. However, appropriate validation studies, are still lacking. Eleven healthy, moderately trained subjects underwent 3 incremental exercise tests. Ventilation, oxygen uptake (V̇o
2), CO2 production (V̇co
2), and HRV were measured continuously. Exercise testing was performed in 3 oxygen (FiO2) conditions of inspired air (14, 21, and 35% of oxygen). Participants and assessors were blinded to the FiO2 conditions. Two research teams assessed VT2s and HRVT2s independently from each other. Mean workloads corresponding to VT2 and HRVT2 in hypoxia were, respectively, 19 ± 17% (p = 0.01) and 15 ± 15% (p = 0.1) lower in comparison with hyperoxic conditions. Bland-Altman analysis showed low estimation bias (2.2%) and acceptably precise 95% limits of agreement for workload −15.7% to 20.1% for all FiO2 conditions. Bias was the lowest under normoxic conditions (1.1%) in comparison with hypoxia (3.7%) and hyperoxia (4.7%). Heart rate variability–based AT2 assessment had a most acceptable agreement with VT2 under normoxic conditions. This simple HRVT2 assessment may have potential applications for exercise monitoring in commercial fitness settings.
Application of the Repetitions in Reserve-Based Rating of Perceived Exertion Scale for Resistance Training
Authors: Helms Eric R. , Cronin John , Storey Adam , Zourdos Michael C.
Published: May 2016

RATINGS OF PERCEIVED EXERTION ARE A VALID METHOD OF ESTIMATING THE INTENSITY OF A RESISTANCE TRAINING EXERCISE OR SESSION. SCORES ARE GIVEN AFTER COMPLETION OF AN EXERCISE OR TRAINING SESSION FOR THE PURPOSES OF ATHLETE MONITORING. HOWEVER, A NEWLY DEVELOPED SCALE BASED ON HOW MANY REPETITIONS ARE REMAINING AT THE COMPLETION OF A SET MAY BE A MORE PRECISE TOOL. THIS APPROACH ADJUSTS LOADS AUTOMATICALLY TO MATCH ATHLETE CAPABILITIES ON A SET-TO-SET BASIS AND MAY MORE ACCURATELY GAUGE INTENSITY AT NEAR-LIMIT LOADS. THIS ARTICLE OUTLINES HOW TO INCORPORATE THIS NOVEL SCALE INTO A TRAINING PLAN.
Influence of Fine Aggregate Content on Low-Temperature Cracking of Asphalt Pavements
Authors: Ma H. , Zhou C. , Feng D. , Sun L.
Published: May 2016

Low-temperature cracking occurs on some asphalt pavements even though the high-performance grade (PG) binders are applied in asphalt mixtures. It is neither realistic nor economic to solve the problems related to low-temperature cracking on asphalt pavements by purely using high PG binders. Other factors need to be investigated so that this type of distress can be further restrained. This study focuses on investigating the effect of fine aggregates on the low-temperature cracking on asphalt pavements. Low-temperature cracking was monitored and recorded on asphalt pavements in a cold, northeast area of China. Cores were drilled on the spots where low-temperature cracking occurred, and the aggregate gradations of the drilled cores were analyzed in the laboratory. An index called the Fine Aggregate Content Deviation Index (FACDI) was defined as the difference between the actual fine aggregate content and the lower limit of fine aggregate content in the designed aggregate gradation. A positive relation was observed between the FACDI and the cracking index of asphalt pavements. It was demonstrated that the fine aggregate content was another important factor that influences low-temperature cracking of asphalt pavement. The increase of fine aggregate content was found to jeopardize the resistance of asphalt mixture on low-temperature cracking. Based on FACDI, fine aggregate's contents in asphalt mixtures of asphalt layers can be recommended to ensure an asphalt pavement with good low-temperature performance.
Potential of Portland-Limestone Cement to Improve Performance of Concrete Made With High Slag Cement and Fly Ash Replacement Rates
Authors: Shannon J. , Howard Isaac L. , Tim Cost V.
Published: May 2016

Aggressive use of supplementary cementitious materials (SCMs) in concrete is becoming more appealing due to potential for cost effectiveness, reduced environmental impact, enhanced durability, and increased sustainability. Constructability, though, is often less attractive as time of set and early strength development can be delayed. This paper investigated the merits of incorporating portland-limestone cement (PLC) to improve concrete sustainability and performance when rounded gravel aggregates (most sustainable for some markets) were used in conjunction with dual SCMs proportioned for 50 % to 70 % total cement replacement. The family of concrete mixtures evaluated have not been widely studied with PLC (in the US or elsewhere). Mixtures containing PLC designed for improved synergies in the US construction market were compared to similar variations containing ordinary portland cement (OPC). PLC was shown to be able to produce concrete mixtures of greater compressive strength and lower set times compared to OPC in some, but not all, conditions. Individual mixture performance varied based on SCM use, PLC properties, and aggregate properties.
Applying MQCAC and Fuzzy TOPSIS to Improve the Unleaded Gasoline Quality
Authors: Chen K. -S. , Hsu C. -H. , Ouyang L. -Y. , Yang C. -M.
Published: May 2016

This study proposes a novel hybrid method that integrates a new multi-quality characteristic analysis chart (MQCAC) and a fuzzy technique for order of preference by similarity to ideal solution (fuzzy TOPSIS). First, all the data of nominal-the-best, larger-the-better, and smaller-the-better quality characteristics were transferred into new evaluation data by using a change-of-variable technique. Furthermore, a new MQCAC was developed to measure whether all the quality characteristics of a product satisfy specifications. All substandard quality characteristics were regarded as alternatives when conducting fuzzy TOPSIS analysis. Subsequently, the top priority substandard quality characteristic for improvement in light of resource requirements and the performance improvement potential under a fuzzy environment was obtained using the proposed method. Finally, a real-world case study is presented to demonstrate the practicality and feasibility of the proposed method.
EWMA np Control Chart for the Weibull Distribution
Authors: Arif O. -H. , Aslam M. , Jun C. -H.
Published: May 2016

In this paper, we will present the design of an attribute exponentially weighted moving average (EWMA) control chart based on the number of failures under a time-truncated life test. It is assumed that the lifetime of the product follows the Weibull distribution. The performance of the proposed chart is discussed in terms of the average run length. The efficiency of the proposed chart is given over the existing attribute control chart. The proposed chart performs better than the existing chart in detecting shifts in the manufacturing process, as compared to the existing control chart. A simulation example is given to illustrate the proposed chart.
Intraclass Correlation Test-Score Reliability of a Single Trial
Authors: Zanevskyy I. , Zanevska L.
Published: May 2016

The aim of the research was to improve a method of estimation of test-score reliability of a single trial. The hypothetical correlation between the first trial and a trial on other occasions assuming no learning or fatigue effects was determined. It was shown that a valuation of the single measure test reliability using an intraclass correlation coefficient may show an understated assessment because trends in the repeated trials caused by combination of fatigue and training effects. A method of elimination of systematic changes in repeated trials based on linear regression was proposed. In a numerical example, elimination of these trends resulted in an improvement of assessment of the test score reliability from a near acceptable level (0.785) as ICC (3,1) to an acceptable level (0.803) as ICC (1,1).
Performance Analysis of Voltage-Stateless Controller for Renewable-Energy-Supported Shunt-Active Power Filter
Authors: Ramakrishnan C. , Vijayan S.
Published: May 2016

The shunt-active power filter (APF) is one of the most efficient solutions to power-quality issues. The topology has a parallel, connected voltage-source inverter, which offers compensation for current-based disturbances. The effectiveness of compensation is influenced by the control technique employed. Moreover, the controller decides the required quantity of sensors and measurement practices; therefore, it decides related costs. This study uses a second-order generalized integrator (SOGI) to extract the reference current of shunt APF. The proposed strategy uses only measuring of the converter and load currents, thereby does not require voltage measurement and sensors. The proposed topology uses the photovoltaic (PV) energy with an energy-storage unit to generally meet the active power requirement of the utility grid and provides the sustainable compensation of current disturbances and voltage interruption of the three-phase distribution system. The PV-supported shunt APF, tested with different types of loads, can evaluate the performance of the system under steady-state and dynamic conditions. To confirm the efficiency of the proposed controller for PV-supported shunt APF, the simulation and experimental results are presented.
Pro-inflammatory signaling by 24,25-dihydroxyvitamin D3 in HepG2 cells
Authors: Wehmeier Kent , Onstead-Haas Luisa M , Wong Norman C W , Mooradian Arshag D , Haas Michael J
Published: May 2016

The vitamin D metabolite 24,25-dihydroxyvitamin D3(24, 25[OH]2D3) was shown to induce nongenomic signaling pathways in resting zone chondrocytes and other cells involved in bone remodeling. Recently, our laboratory demonstrated that 24,25-[OH]2D3but not 25-hydroxyvitamin D3, suppresses apolipoprotein A-I (apo A-I) gene expression and high-density lipoprotein (HDL) secretion in hepatocytes. Since 24,25-[OH]2D3has low affinity for the vitamin D receptor (VDR) and little is known with regard to how 24,25-[OH]2D3modulates nongenomic signaling in hepatocytes, we investigated the capacity of 24,25-[OH]2D3to activate various signaling pathways relevant to apo A-I synthesis in HepG2 cells. Treatment with 24,25-[OH]2D3resulted in decreased peroxisome proliferator-activated receptor alpha (PPARα) expression and retinoid-X-receptor alpha (RXRα) expression. Similarly, treatment of hepatocytes with 50 nM 24,25-[OH]2D3for 1–3 h induced PKCα activation as well as c-jun-N-terminal kinase 1 (JNK1) activity and extracellular-regulated kinase 1/2 (ERK1/2) activity. These changes in kinase activity correlated with changes in c-junphosphorylation, an increase in AP-1-dependent transcriptional activity, as well as repression of apo A-I promoter activity. Furthermore, treatment with 24,25-[OH]2D3increased IL-1β, IL-6, and IL-8 expression by HepG2 cells. These observations suggest that 24,25-[OH]2D3elicits several novel rapid nongenomic-mediated pro-inflammatory protein kinases targeting AP1 activity, increasing pro-inflammatory cytokine expression, potentially impacting lipid metabolism and hepatic function.
Genomic Prediction for Quantitative Traits Is Improved by Mapping Variants to Gene Ontology Categories inDrosophila melanogaster
Authors: Edwards Stefan M , Sørensen Izel F , Sarup Pernille , Mackay Trudy F C , Sørensen Peter
Published: May 2016

Predicting individual quantitative trait phenotypes from high-resolution genomic polymorphism data is important for personalized medicine in humans, plant and animal breeding, and adaptive evolution. However, this is difficult for populations of unrelated individuals when the number of causal variants is low relative to the total number of polymorphisms and causal variants individually have small effects on the traits. We hypothesized that mapping molecular polymorphisms to genomic features such as genes and their gene ontology categories could increase the accuracy of genomic prediction models. We developed a genomic feature best linear unbiased prediction (GFBLUP) model that implements this strategy and applied it to three quantitative traits (startle response, starvation resistance, and chill coma recovery) in the unrelated, sequenced inbred lines of the Drosophila melanogaster Genetic Reference Panel. Our results indicate that subsetting markers based on genomic features increases the predictive ability relative to the standard genomic best linear unbiased prediction (GBLUP) model. Both models use all markers, but GFBLUP allows differential weighting of the individual genetic marker relationships, whereas GBLUP weighs the genetic marker relationships equally. Simulation studies show that it is possible to further increase the accuracy of genomic prediction for complex traits using this model, provided the genomic features are enriched for causal variants. Our GFBLUP model using prior information on genomic features enriched for causal variants can increase the accuracy of genomic predictions in populations of unrelated individuals and provides a formal statistical framework for leveraging and evaluating information across multiple experimental studies to provide novel insights into the genetic architecture of complex traits.
What’s happening when nothing’s happening? Combining eyetracking and keylogging to explore cognitive processing during pauses in translation production
Authors: Kruger Haidee
Published: May 2016

This article investigates whether a combination of eyetracking and keylogging can yield a better understanding of the cognitive processing that occurs during pauses in translation production. It analyses the interaction between a number of temporal and spatial variables associated with pausing (including pause duration, the syntactic location of the pause and reading behaviour during the pause). Eight third-year students of translation, translating from English to Afrikaans, translated a 180-word text while their keystrokes and eye movements were recorded. Pauses were defined by means of a predetermined cut-off point, and coded for the temporal and spatial variables above. The relationships between these variables form the focus of the analysis. The findings of the study point to a complex relationship between pause duration, the syntactic position of the pause, syntactic asymmetries between the languages involved, reading behaviour and cognitive effort.
Eating and drinking seen through translation: A study of food-related translation difficulties and techniques in a parallel corpus of literary texts
Authors: Oster Ulrike , Molés-Cases Teresa
Published: May 2016

This paper presents an exploratory study on translators’ decisions when encountering food-related translation difficulties in a parallel corpus of German original narrative texts and their translations into Spanish and Catalan. For this purpose, all food- and drink-related lexemes in the German original texts were extracted and classified in semantic groups. As a second step, the source and target text fragments of lexemes related to foodrelated cultural referents, metaphorical expressions or ways of eating and drinking were extracted and analysed in view of the techniques applied by the translators of both language combinations. The results obtained through the classification and quantification of the translation techniques in these three domains allow conclusions to be drawn regarding a) the existence of foreignizing or domesticating tendencies in the translation of food terms, b) the ways translators deal with action verbs that encompass multiple meaning aspects and c) the degree of metaphoricity and food-relatedness in the translation of metaphorical expressions.
Formulaicity in and across film dialogue: Clefts as translational routines
Authors: Pavesi Maria
Published: May 2016

Formulaicity, an inherent feature of language, may typify film discourse. Imitation of conversation is posited to extend to conversational routines in original fictive orality, whereas the language of dubbing is believed to increase its formulaicity through translational routines, reiterated translation solutions generating recurrent strings in the target texts. Despite the role assigned to formulaicity, few corpus-based investigations have set out to account for the types, frequency and functions of formulas in both original and dubbed audiovisual dialogue. By drawing on the Pavia Corpus of Film Dialogue − a unidirectional English–Italian parallel corpus totalling about 500,000 words − this study analyses a special kind of formulas, English demonstrative clefts, and their formulaic translations. It evaluates how closely film language reproduces these frequent features of conversational formulaicity, and to what extent source-based patterns are resorted to in dubbing. The results show that demonstrative clefts of the type That’s what I see are frequent in Anglophone film language, where they contribute to the naturalness of the register. In the Italian translations, English demonstrative clefts give way to recurring solutions that are calqued on the original triggers, exhibit a degree of fixedness in the target language and contribute to the specificity of dubbed Italian.
Covert multilingualism: The case of the translation policy in France and Belgium during the French Revolution and the Napoleonic era
Authors: Schreiber Michael
Published: May 2016

The language policy of the French Revolution is known today especially for the imposition of the national language and the oppression of the dialects and regional languages in France. In my contribution, I want to focus on a less known aspect: the translation policy. From 1790 on, several decrees stipulated the translation of national laws and decrees into the regional languages in France. From the mid-1790s on, the translation policy was extended to other countries and regions under French rule. I will consider the case of the Southern Netherlands (Belgium), annexed by France in October 1795 and under French administration until the end of the Napoleonic era. According to the opinio communis, the period under consideration was strictly monolingual in France and Belgium, with French as the only language of administration and justice. I will argue that there was a covert multilingualism, that today is often ignored.
Central European Connections of Six Manuscript Organ Tablature Books of the Reformation Era from the Region of Zips (Szepes, Spiš)
Authors: Hulková Marta
Published: May 2016

Tablature notations that developed in the sixteenth century in the field of secular European instrumental music had an impact also on the dissemination of purely vocal and vocal-instrumental church music. In this function, the so-called new German organ tablature notation (also known as Ammerbach’s notation) became the most prominent, enabling organists to produce intabulations from the vocal and vocal-instrumental parts of sacred compositions. On the choir of the Lutheran church in Levoča, as parts of the Leutschau/Lőcse/Levoča Music Collection, six tablature books written in Ammerbach’s notation have been preserved. They are associated with Johann Plotz, Ján Šimbracký, and Samuel Marckfelner, local organists active in Zips during the seventeenth century. The tablature books contain a repertoire which shows that the scribes had a good knowledge of contemporaneous Protestant church music performed in Central Europe, as well as works by Renaissance masters active in Catholic environment during the second half of the sixteenth century. The books contain intabulations of the works by local seventeenth-century musicians, as well as several pieces by Jacob Regnart, Matthäus von Löwenstern, Fabianus Ripanus, etc. The tablatures are often the only usable source for the reconstruction of sixteenth- and seventeenth-century polyphonic compositions transmitted incompletely.
Unveröffentlichte Liszt-Briefe aus Weimar und Dresden
Authors: Hamburger Klára
Published: May 2016

This documentary contains 16 Liszt-letters preserved at the Goethe-Schiller- Archiv (GSA) in Weimar and further 14 items from the Sächsische Landesbibliothek – Staats- und Universitätsbibliothek (SLUB) in Dresden. The Weimar letters include those in which Liszt addressed (in French) Ignaz Moscheles and Julius Benedict, both German musicians living in London, about his 1840 concert tour in England. Also, he wrote in French to singer Pauline Viardot-Garcìa, Madame Érard, and his Neapolitan pupil Luisa Cognetti. His letters in German to Hermann Levi deal with Richard Wagner. In another letter Liszt is asking the Vienna Home Secretary Baron Alexander von Bach, to have his Gran Mass published at the state administration’s expense. His letters to Count Sándor Teleki and Ede Reményi concern Hungarian musical life. Liszt is giving instructions for the publishing of his work Hymne de l’enfant à son réveil to his Hungarian publisher Nándor Táborszky and writing a dry refusal to his former Hungarian pupil Sándor Bertha. The envelope of a letter to Madame Munkácsy has a mistake in the orthography of the family name. The documents from Dresden include an Albumblatt Liszt wrote for Clara Schumann, a recommendation for Heinrich Ehrlich, the composer of the first Lento-theme of Liszt’s Hungarian Rhapsody no 2. Further letters were written to Laura Kahrer (one of them having been published in a slightly altered manner by La Mara) and a series of eight letters to Liszt’s Swiss disciple Bertrand Roth.
Musical Speech Analogy in Ernő Dohnányi’s Der Schleier der Pierrette
Authors: Lebon Daniel-Frédéric
Published: May 2016

Following a brief survey into the history of the ballet d’action, the article examines the techniques of musique parlante Dohnányi used in his pantomime Der Schleier der Pierrette. The subcategories illustrated with music examples include the direct speech imitation (focusing on the syllabic and rhythmic structure of single words) and the musical analogy of the question-answer complex. The analytical overview is extended to further indirect categories such as the recitative-like structures (built up not merely on speech, but on an already emancipated equivalent, the instrumental recitative) and the leitmotif technique which – although being more distant from speech – can, in some cases, still be seen as part of musique parlante. In an attempt to describe the position of Der Schleier der Pierrette in ballet music history, the author addresses Béla Bartók’s reception of Dohnányi’s pantomime and distinguishes the tradition followed by Dohnányi from the denial of musique parlante characteristic of the works Igor Stravinsky composed for the Ballets Russes.
Did He Mean It?
Authors: Taruskin Richard
Published: May 2016

The program note I want to gloss concerns the Symphony in Three Movements, which was composed over the years 1942 to 1945 and first performed, on 24 January 1946, by the New York Philharmonic-Symphony Orchestra under the composer’s baton. In 1963 Stravinsky seemed to have had a change of heart that rendered him willing to admit what he had formerly denied, even if he still needed to cloak the admission in paradox. Is it evidence that (to recall a book of outdated centennial essays) Stravinsky the musician never really meant what Stravinsky the modernist averred? We’ll never know. Meanwhile, we’ll go on performing and interpreting Stravinsky’s music the way not he but we need to hear it. As long as we do that, his work will live.
A vesetranszplantáció pozitív hatásai a betegek angiológiai státuszára. Az artériás funkció (stiffness) noninvazív mérésének lehetséges szerepe az előrejelzésben
Authors: Kovács Dávid Ágoston , Asztalos László , Laczik Renáta , Fedor Roland , Szabó László , †Lőcsey Lajos , Soltész Pál
Published: May 2016

Introduction: Development of atherosclerosis is accelerated in kidney transplant patients. Impaired metabolic pathways have complex effect on the arterial wall which can be measured by non-invasive techniques. Only few data are available on the change of stiffness parameters in the postoperative course. Therefore, in this study the authors analysed the stiffness parameters of kidney transplant recipients during the perioperative period. Aim: Non-invasive clinical trial of the arterial functional parameters in the early postoperative period. Method: Seventeen successful primary kidney transplant patients with uneventful postoperative period (8 females, 9 males; age, 46.16 ± 12.19 years) were involved in this short-term prospective longitudinal study. The authors analysed correlations between non-invasively assessed stiffness parameters (pulse wave velocity PWV, augmentation index - AIx). Stiffness parameters were measured with a TensioMed Arteriograph. These parameters were assessed before the transplantation, as well as 24 hours, 1 and 2 weeks after surgery under standard conditions. Results: It was found that PWV (p = 0.0075) and AIx (p = 0.013) improved significantly. There was no significant change in case of PP and the other monitored parameters. Serum creatinine decreased (p = 0.0008) and glomerular filtration rate increased significantly (p = 0.0005). Conclusions: Along with the available data in the literature, the findings suggest that kidney transplantation has a positive effect on the arterial function. Improvement can be detected non-invasively with Arteriograph in the early postoperative period. Orv. Hetil., 2016, 157(24), 956–963.
Paroxysmalis nocturnalis haemoglobinuriával szövődött várandósság ritka esete
Authors: Horányi Dániel , Várkonyi Andrea , Nagy Gyula Richárd , Bodó Imre , Masszi Tamás
Published: May 2016

Paroxysmal nocturnal hemoglobinuria is a rare hematological disease. It is associated with increased maternal and fetal complications to such an extent that pregnancy has been considered relatively contraindicated in woman with paroxysmal nocturnal haemoglobinuria. Recently, eculizumab, a monoclonal antibody, has been shown to decrease complications during pregnancies. The highest risk is thromboembolic complication and, therefore, anticoagulant is a standard therapy during pregnancy. In the presented case, a 29-year-old woman with a 5-year history of paroxysmal nocturnal haemoglobinuria had a pregnancy. It was her first pregnancy and was complicated by a sinus thrombosis at the 11th gestational week. After the introduction of eculizumab treatment, the remaining period of pregnancy and delivery were uncomplicated. There are only a few cases in the literature about pregnancy in woman with paroxysmal nocturnal hemoglobinuria who are treated with eculizumab. This monoclonal antibody seems to be safe and it likely prevents many of the complications otherwise observed. Orv. Hetil., 2016, 157(23), 916–918.
A Magyar Alvásdiagnosztikai és Terápiás Társaság módszertani ajánlása a közúti járművezetők egészségi alkalmasságának vizsgálatához az obstruktív alvási apnoe szindróma vonatkozásában
Authors: Szakács Zoltán , Ádám Ágnes , Annus János Kristóf , Csatlós Dalma , László Andrea , Kalabay László , Torzsa Péter
Published: May 2016

Obstructive sleep apnea is the most frequent sleep-disordered breathing. The prevalence of sleep apnea in the general population is 2–4% and the main characteristics of the disease are the intermittent cessation or substantial reduction of airflow during sleep, which is caused by complete, or near complete upper airway obstruction. Decreased airflow is followed by oxygen desaturation and intermittent arousals. Untreated patients are 4–6 times more likely to cause traffic accidents than their healthy counterparts. The aims of the obstructive sleep apnea screening are to prevent and reduce the incidence of serious car accidents, which are often caused by one of the most dangerous sleep disorders. Since April 1, 2015 a modification of the 13/1992 regulation has been in force in Hungary which orders screening of obstructive sleep apnea during medical checkup of drivers. The Hungarian Society for Sleep Medicine made a guideline according to the regulation which was adapted to national circumstances and family doctors, occupational health specialists can more easily screen obstructive sleep apnea in suspected patients. In sleep ambulances the disease can be diagnosed and effective treatment can be started. Patients receiving appropriate treatment and with appropriate compliance can get their driving licence under regular care and control. Orv. Hetil., 2016, 157(23), 892–900.
Metformin – újabb adatok egy megbízható és hatékony „régi” vércukorcsökkentő készítményről
Authors: Winkler Gábor
Published: May 2016

Metformin is the basic drug of antihyperglycemic therapy in type 2 diabetes: according to actual therapeutic guidelines, it should be given in the absence of contraindications or intolerance during the whole course of the disease even after the initiation of insulin therapy. Recently more and more details have been explored regarding the molecular background of its effects, however, in parallel with the enormous growing knowledge, the number of questions still waiting to be answered has also grown. This review article deals with data already crystallized as well as with details not definitely cleared up. Genetic polymorphisms as well as potential drug interactions influencing the effects of metformin are also briefly summarized. Orv. Hetil., 2016, 157(23), 882–891.
Adjusting the 17β–Estradiol-to-Androgen Ratio Ameliorates Diabetic Nephropathy
Authors: Inada Akari , Inada Oogi , Fujii Nobuharu L. , Nagafuchi Seiho , Katsuta Hitoshi , Yasunami Yohichi , Matsubara Takeshi , Arai Hidenori , Fukatsu Atsushi , Nabeshima Yo-ichi
Published: May 2016

Diabetes is manifested predominantly in males in experimental models, and compelling evidence suggests that 17β-estradiol (E2) supplementation improves hyperglycemia in humans. We previously generated a severely diabetic transgenic (Tg) mouse model by β-cell–specific overexpression of inducible cAMP early repressor (ICER) and found that male but not female ICER-Tg mice exhibit sustained hyperglycemia and develop major clinical and pathologic features of human diabetic nephropathy (DN). Thus, we hypothesized that differences in circulating hormone levels have a key role in determining susceptibility to diabetes. Here, we examined whether DN in male ICER-Tg mice is rescued by adjusting the androgen-to-E2 ratio to approximate that in normoglycemic female ICER-Tg mice. We treated hyperglycemic male ICER-Tg mice with orchiectomy (ORX), E2 pellet implantation, or both. E2 pellet implantation at an early stage of DN with or without ORX caused a rapid drop in blood glucose and a dramatic increase in β-cell number, and it markedly inhibited DN progression [namely, E2 reduced glomerulosclerosis, collagen IV deposition and albuminuria, and prevented hyperfiltration]. Furthermore, E2 pellet implantation was more effective than ORX alone and induced a remarkable improvement, even when initiated at advanced-stage DN. In contrast, induction of normoglycemia by islet transplant in ICER-Tg mice eliminated albuminuria but was less effective than E2+ORX in reducing glomerulosclerosis or collagen IV deposition and hyperfiltration. These findings indicate that E2 treatment is effective, even after establishment of DN, whereas glucose normalization alone does not improve sclerotic lesions. We propose that E2 intervention is a potential therapeutic option for DN.
Implementing universal design in a Norwegian context: Balancing core values and practical priorities
Authors: Lid Inger Marie
Published: May 2016

How can urban planning processes include perspectives from people with disabilities? This paper discusses the implementation of universal design (UD) and accessibility in a local urban context. Universal design consists of both core values, such as inclusion and equal status, and specific design initiatives, such as design of pavement surfaces and benches. The aim of implementing universal designing strategies is to achieve equal access for all citizens. The paper interprets the urbanist Henri Lefebvre's notion of the right to the city as a right to participate in urban life and thus a dimension of equal citizenship on a very concrete level. The right to participate in urban life is closely linked to access to the built environment. Based on an empirical study of an urban redesign project, I argue that equal access must imply both access to public places and to political processes.
Инновационная экономика России: проблемы и перспективы экономического роста
Authors: Кравец Александр Витальевич
Published: May 2016

В статье рассматривается причины кризисной ситуации в российской экономике, начиная с 2012 года, анализируется влияние ряда факторов на динамику экономических показателей, оцениваются причины сложностей перехода экономики России на новый технологический уклад, который уже формируется в странах Запада. Исследуются взаимосвязи экономического роста российской экономики, формирования в стране нового технологического уклада с креативностью бизнеса, инноваций и формированием кластеров на территории Российской Федерации.Материал статьи может быть полезен научным работникам, занимающихся макроэкономическими исследованиями, влиянием на макроэкономические показатели внедрения в производство инновационных разработок, анализом развития кластеров в регионах России.
Применение отдельных положений теории совместимости при формировании и использовании интеллектуальных ресурсов
Authors: Светлов Илья Евгеньевич
Published: May 2016

В статье обосновывается необходимость использования положений теории совместимости при формировании интеллектуальных ресурсов хозяйствующих субъектов в современных условиях. Дано краткое описание ряда изменений экономических отношений и производственных процессов, характеризующих инновационную экономику и процессы перехода к последним технологическим укладам и Индустрии 4.0. Представлены возможности применения положений теории совместимости как относительно интеллектуального капитала отдельного предприятия, с целью повышения эффективности его функционирования и построения когнитивной стратегии; так и в отношении сетевых структур, на примере образовательного пространства, при подборе субъектов его формирующих.Материалы статьи могут быть применены для повышения эффективности функционирования интеллектуального капитала компаний, при разработке и реализации когнитивной стратегии предприятия, для совершенствования взаимодействия хозяйствующих субъектов при формировании интеллектуальных ресурсов для современных предприятий и сопроизводстве на основе интеллектуальных капиталов. Предложения и результаты, изложенные в статье, могут быть полезны сотрудникам инновационных компаний, предпринимателям, представителям учреждений профессионального образования, а также всем, интересующимся вопросами инновационного менеджмента и проблемами инновационного развития.
Требования к программам, реализуемым в компании на принципах образовательного аусорсинга
Authors: Кротов Александр Юрьевич
Published: May 2016

В статье представлен предложенный автором подход к формированию требований к образовательным программам, реализуемым предприятием на принципах аутсорсинга. Такие требования формируются на основе общего перечня требований к компетенциям работников разного уровня компании, которые должны быть получены в процессе обучения, и перечня их компетенций, которые могут быть получены в рамках обучения работниками самой компании.
Экономическое взаимодействие государства и бизнеса как условие формирования инновационного предпринимательства в России
Authors: Кравец Александр Витальевич , Кашин Артем Васильевич
Published: May 2016

В статье рассматриваются определяющие факторы становления инновационной национальной экономики России в целом и необходимость развития инновационного предпринимательства, как пути решения проблемы инновационного развития страны. Анализируются отдельные факторы внешней и внутренней среды и их влияние на инновационную деятельность бизнеса в России. Особо рассматривается роль государства в формировании инновационной национальной экономики в России. Материал статьи может быть полезен научным работникам, занимающихся проблемами инновационного развития на национальном и региональном уровнях, работникам государственных структур.
Знания как базовый фактор экономического роста в условиях перехода к неоиндустриальной парадигме
Authors: Жаворонкин Антон Владимирович
Published: May 2016

Исследование направлено на решение актуальной на сегодняшний день проблемы интенсификации экономического роста в условиях перехода к новой экономической парадигме, обусловленной неоиндустриализацией общества и характерных для такого перехода возникновения «экономики знаний», показателях, ее определяющих, и факторах роста. Решение данной проблемы в статье осуществляется посредством ретроспективного анализа понятия экономики знаний, ее структуры и классификаций знаний как основы ее функционирования, обзора существующих методик расчета показателей, выявления стран, лидирующих в преобладании локомотивных факторов, являющихся драйверами экономического роста на современном этапе развития экономики, а также приведен региональный опыт аккумуляции, ретрансляции и тиражирования знаний посредством трансфера человеческого капитала. Работа проведена с изучением научной литературы и использованием методов горизонтального и вертикального анализа, деконструкции, моделирования, системного подхода. В процессе осуществления исследования были изучены работы ведущих отечественных и зарубежных авторов, проведен анализ публикаций и статистических баз данных международных институтов развития, национальных и международных статистических и консалтинговых агентств. Данная статья представляет ценность для исследователей в области экономики знаний и человеческого капитала, профильных министерств и ведомств и содержит рекомендации по совершенствованию промышленной политики и институциональной модернизации для достижения повышения темпов экономического роста.
Формирование инновационной состоятельности промышленного предприятия
Authors: Мыслякова Юлия Геннадьевна , Кислов Роман Сергеевич
Published: May 2016

Статья посвящена вопросам развития инновационной деятельности промышленных предприятий в условиях новой индустриализации, определяющих выживаемость наукоемкого бизнеса через активизацию разработок и реализации НИОКР высокого качества, способных создавать востребованную наукоемкую продукцию, как на национальном, так и мировом уровне. В статье авторы расширяют традиционный подход к пониманию инновационной деятельности путем ввода в научный оборот нового понятия – «инновационная состоятельность». На базе сравнительно-критериального анализа таких базовых дефиниций инновационного менеджмента, как инновационный потенциал, инновационная активность, инновационная восприимчивость, уточняется место инновационной состоятельности в практике промышленных предприятий, при этом обосновывается, что она является эволюционным этапом развития инновационной деятельности в цепочке инновационный потенциал – инновационная активность – инновационная восприимчивость – инновационная состоятельность. В статье выделены отличительные особенности инновационной состоятельности наукоемкого бизнеса и предложен ряд рекомендаций, ориентированных на ее институционализацию. Представленные результаты исследования будут интересны студентам, магистрантам, ученым, руководителям крупных и малых предприятий, занимающимся вопросами совершенствования методов развития и стимулирования инновационной деятельности промышленных предприятий, повышения конкурентоспособности наукоемкого бизнеса в условиях новой индустриализации, разработки стратегий инновационно-экономического развития промышленных предприятий.
Интегрированный риск-менеджмент: инновационные модели реализации
Authors: Скобелева Инна Петровна , Легостаева Надежда Викторовна , Калашник Надежда Евгеньевна
Published: May 2016

В статье предложена модель интеграции риск-менеджмента в общий контур системы управления компании на основе консолидации потенциалов инструментария BSC, SWOT-анализа и PESTLE-анализа; обоснованы ее базовые компоненты и их характеристика. Представленный подход способствует полноценной реализации принципов риск-ориентированного управления и позволяет оценить влияние риск-потенциала на достижение стратегических целей компании. Статья адресована специалистам-практикам, чья деятельность связана с риск-менеджментом в компаниях реального сектора, специалистам научных организаций, учащимся и преподавателям высших учебных заведений.
Развитие партисипативного управления на промышленных предприятиях
Authors: Потуданская Вера Федоровна , Алифер Евгения Олеговна
Published: May 2016

В статье рассмотрены вопросы партисипативного управления как мотивационные составляющие формирования оплаты труда. Представлены структурные компоненты процесса реализации партисипативного управления на предприятии и выявлены основные элементы, закрепленные в нормативной документации в рамках системы менеджмента качества крупного промышленного предприятия Омской области. Данная статья имеет прикладное значение для развития партисипативного управления как инструмента организации оплаты труда и может быть полезна научным работникам, аспирантам, руководителям и специалистам промышленных предприятий.
Проблема роли и места экономики в обществе в социально-экономических исследованиях
Authors: Орлянский Евгений Анатольевич
Published: May 2016

Статья посвящена проблеме определения роли и места экономики в обществе в различных социально-экономических концепциях. Рассматриваются две противоположные концепции: концепция экономизма и альтернативная концепция представителя Исторической школы Вернера Зомбарта. Актуальность такого анализа выявляется в том, что эти подходы отражают сущность самих хозяйственных систем, их кризисов и методов антикризисной политики.
Стратегические концепции управления человеческими ресурсами и их влияние на инновации
Authors: Тароян Ваган Мамбреевич
Published: May 2016

В статье рассматриваются основные стратегические концепции управления человеческими ресурсами (УЧР) и их влияние на развитие инновационной деятельности в организации. В настоящее время ключевое значение в достижении постоянного конкурентного преимущества компании придается росту инноваций. Несмотря на определенные различия ряда концепций УЧР, в большинстве своей они являются акцентируемыми формами участия сотрудников в управлении. Данная статья будет полезна исследователям, занимающимся проблемами управления человеческими ресурсами в инновационных организациях.
Актуальные проблемы развития высшего образования в российских регионах
Authors: Сысоев Александр Петрович , Суханова Наталия Виленовна
Published: May 2016

В статье исследуются институциональные изменения, которые произошли в региональном высшем образовании в связи с принятием ФЗ № 273 «Об образовании в Российской Федерации». Показана роль майских (2012 г.) Указов Президента РФ, законодательных и нормативных правовых актов субъектов РФ, приказов и распоряжений Минобрнауки РФ в модернизации и развитии регионального высшего образования. В заключении статьи содержатся краткие выводы, отражающие позицию авторов по совершенствованию организации регионального высшего образования, улучшению его содержания и качества. Данная публикация может быть полезна сотрудникам региональных министерств (департаментов) образования, научным и практическим работникам, интересующимся вопросами повышения креативности отечественного высшего образования.