bluuebunny/crossref_metadata_2025 huggingface dataset:
KNOWLEDGE REGARDING TERATOGENIC DRUGS AMONG WOMEN IN A SELECTED HOSPITAL AT MANGALORE WITH A VIEW TO DEVELOP AN INFORMATION BOOKLET: A DESCRIPTIVE SURVEY APPROACH
Authors: Vinaya Kumary. T  , Manisha Shrivastava  , Pamela Shalini Joseph  , Sudha Gautam  , Ruby Singh  , Tanima Verma
Published: November 2022

Background of the study: Caution with regard to dietary intake during pregnancy has been advised since ancient times and this is true even today, more so for the use of drugs in pregnancy. Drug use during early pregnancy is not different from non-pregnant women. The knowledge of women regarding teratogenic drugs has an effect on their health.Methodology: Quantitative approach with a typical descriptive design was adopted in the present study. Purposive sampling technique was used for the selection of the sample. A close-ended structured knowledge questionnaire was used to assess the knowledge of women on teratogenic drugs. The study was conducted in selected Hospital, at Mangalore, with the sample size of 100 women. After data collection, the information booklets regarding teratogenic drugs were distributed to women to improve their knowledge.Results: Descriptive and inferential statistics were used to analyse the data. Assessment of the level of knowledge of the women showed that the highest percentage (64%) of the sample had moderate knowledge; 25% of the women had poor knowledge, 9% of the women had good knowledge and only two percent of the women had very good knowledge on teratogenic drugs. Present study results reveals that there was significant association between knowledge score and demographic variable.Conclusion: The overall knowledge regarding teratogenic drugs in the study population was 45.67%. Hence, it is concluded that the knowledge of women was not adequate enough therefore further improvement in knowledge was still needed in this area.
Development of Solid Lipid Nanoparticles with Letrozole for Breast Cancer Treatment: in-vitro and in-vivo evaluation
Authors: Sandhya Rani Mandadi  , Lankalapalli Srinivas
Published: November 2022

Breast cancer (BC) is the most common cancer in women worldwide. Letrozole (LTZ) is a third-generation selective nonsteroidal aromatase inhibitor and one of many anticancer drugs. Conventional LTZ therapies for BC are often administered orally or parenterally and frequently result in severe systemic side effects. To improve this situation, efforts have been made for an advanced drug delivery system that accurately releases the drug at the target site and increases therapeutic efficacy with minimal side effects. Here, we report the delivery system based on poloxomer 188 as a platform for LTZ-based solid lipid nanoparticles (SLNs) in cancer cells. The particle size, PDI, ZP, and DEE % of optimally selected LTZ -SLNs (pH 7.4) were 82.16 ± 7.24 nm, 0.287 ± 0.05, -15.0 ± 8.83 mV, and 57.89 ± 1.22 %, respectively. The SEM of LTZ -SLNs shows hexagonal phase stacking with a nanoflock morphology. The TEM image clearly shows that the introduced LTZ -SLN drugs contain LTZ drugs inside the particles. After 48 hours, it was reported that the percentage of LTZ release was 82.34%. LTZ-SLNs showed significant cytotoxic properties with an IC50 of 2.22ug/ml. The results of histopatholgical study confirmed that LTZ-SLNs can minimize the cytotoxicity of LTZ. Overall, the prepared nanoformulation offers great potential for BC treatment.
A STUDY OF JADIDISM IN THE INDEPENDENCE PERIOD
Authors: Dilafruz Jabborova
Published: November 2022

In this article, the observations of literary scholar K.Kahramanov on his assessment of the life and work of modern literary figures who were victims of repression in Uzbek literary studies and criticism of the independence period as a methodological update.
Safety Culture of Physicians’ Medication in Saudi Arabia
Authors: Yousef Ahmed Alomi  , Mohamed S. Imam  , Randa M. Abdel-Sattar  , Ghada M. Alduraibi  , Aliyah S. Alrowais
Published: November 2022

Objective: The study aims to demonstrate the Physicians’ Medication Safety Culture in Saudi Arabia.Methods: It examines a cross-sectional survey of physicians' medication safety practices in Saudi Arabia. It self-reported an electronic survey of physicians in Saudi Arabia, ranging from intern to consultant level, and physician specialties. The survey included respondents' demographic information about physicians who reported medication safety items in medical care, as well as medications who executed medication safety. With closed-ended questions, the 5-point Likert response scale system was used. The survey monkey system was used to analyze data on the Physicians’ Medication Safety Culture. In this study, the statistical package for social sciences (SPSS), Jeffery's Amazing Statistics Program (JASP), and Microsoft Excel sheet version 16 were used.Results: The total number of responding physicians was 253, with the majority 73 (54.07 %) coming from the central region, which was statistically significant among the areas (p<0.01). The majority of those who responded were from private hospitals 48(18.97%), MOH hospitals 41(16.21%), and University hospitals 40 (15.81%). Furthermore, 72 (60.50%) were female, while 47 (39.50%) were male, with a statistically significant difference (p<0.01). The average frequency of medications safety items reported monthly in medical care was (5.97), with the highest score element being Medication’s wastage services system (6.42), followed by Medications labelling before use (6.31), Medical drug information resources (6.15) and Medication’s safety committee for medical care (6.11). Anticoagulants 33 (33.33 %) and NSAIDs 32 (32.32 %) were the medications used in medication error reporting. Sedation medications 38(38.78%) and muscle relaxant medications 36 (36.73%) were the drugs used in ADR reporting. Antineoplastic 40 (40.00%) and Anti-seizure drug 39 (39.39%) were the most commonly used medicines in the looks like sound-alike system (38.24 %). Anti-arrhythmic 43 (43.88 %) and anti-psychotic medication 40 (40.40%) were the drugs used in the high alert medication system.Conclusion: The Physicians’ Medication Safety Cultures were inadequate and contradictory. Consequently, the physicians instituted non-serious aspects of medication safety culture. Hence, reviewing aspect medications safety cultures in medical practice with a focus on education and training is strongly advised in Saudi Arabia.
Perception of Physician about Medication Safety in Saudi Arabia
Authors: Yousef Ahmed Alomi  , Mohamed S. Imam  , Randa M. Abdel-Sattar  , Ghada M. Alduraibi  , Aliyah S. Alrowais
Published: November 2022

Objective: In this study, we aimed to explore the perception of physician about medication safety in the Kingdom of Saudi Arabia.Methods: In this cross-sectional survey, we aimed to explore the perception of physician about medication safety in Saudi Arabia. We used a self-reported electronic survey questionnaire and distributed it to physicians, from intern to consultant, and specialists in Saudi Arabia. The survey collected demographic information of the physicians and about the perception of medication safety in medical care. Besides, the perception of barriers prevents off implementation of the medication safety system in medical care. We used 5-point Likert response scale system with close-ended questions to obtain responses. The data were collected through the Survey Monkey system and analyzed with the use of Statistical Package of Social Sciences (SPSS), Jeffery’s Amazing Statistics Program (JASP), and Microsoft Excel (version 16) software.Results: A total of 253 physicians responded to the questionnaire, with the majority of them belonged to the central region 73 (54.07%), with statistically significant difference among the areas (p<0.01). Most of the responders were in the age group of 24–35 years 72 (59.02%) with statistically significant differences between all age groups (p<0.01). Most of the physicians were General Practitioners 32 (27.59%), residents 31 (26.72%), and specialists 22 (18.97%) with statistically significant differences between all qualification levels (p<0.05). The average score of Perception of Physician about Medication Safety was (3.13) with high scores obtained for the element was 'the physician felt the continuing education should include the medication's safety (3.33).' and 'the physicians believed that Medication’s wastage services are essential in medical care (3.30).' The average score related to 'perceptions of barriers prevent you from implementing medication safety in medical and surgical care was 3.13. The highest score for the element implemented was a report that would generate extra work (3.34) and an uncertain association between the dental drugs and safety-related issues (3.33) with statistically significant difference between answers (p<0.05).Conclusion: In this study, the Perception of Physician about Medication Safety aspects or obstacles of implementation was found to be inadequate in Saudi Arabia. Therefore, implementing periodic education and training in medication safety in medical care are highly recommended to improve the medication safety aspects in medical care in Saudi Arabia.
ANALYSIS OF PARALINGUISMS INVOLVING HEAD ORGANS
Authors: Barotova Muhiba Orifovna  , Jurayeva Bibish Muhsinovna
Published: November 2022

This article sheds light on the role of the head and its parts in the formation of paralinguistic tools with the help of texts from Uzbek works. Also, the actions that create the most active paralinguisms among the head members and are widely used among the Uzbek people are based on diagrams and tables.
Effect of Methotrexate and Matricaria Chamomile on testis tissue and some antioxidants in Albino rats
Authors: Ibtisam A. Al-Ali  , Rafah S. Almuttairi  , Ameera Jasim Al-Aaraji  , Fakhir M Alzubaidy
Published: November 2022

Objective: Depending on the antioxidant as well as anti-inflammatory properties of Matricaria Chamomile (MC), the current study aimed to investigate if MC could protect testicles against methotrexate (MTX)-induced testicular damage. Methods: 24 male Wistar albino rats were randomly separated into four groups (n=6/each) as follows. G1, the control group was given a single oral daily dose of distilled water (D.W) for 30 days; G2, (MTX group) rats were administered a single oral daily dose of D.W. and in day 28 the animals have received a single IP dosage of MTX; G3 six rats were given an aqueous extract of chamomile flowers at a dose of 200 mg/kg dissolved in 1 ml D.W. and on day 28 the rats have received a single intraperitoneal dose of MTX, and the last group was six rats received a methanolic extract of chamomile flowers at a dose of 200 mg/kg dissolved in 1 ml D.W. and on the day 28 the animals were received a one dosage intraperitoneal of MTX. At the end of the experiment, all animals were anesthetized and sacrificed, blood was also collected for the biochemical test as well as the testicular tissues were removed for histology examination. Results: According to biochemical assessments, notably there was no significant difference between the MTX and the other studied groups. In terms of histological examinations of animals treated with MTX, several pathological changes including vacuolization of seminiferous tubules with a reduced population of germinal epithelium were seen as compared to the control. Animals of G3 and G4 (pre-treatment with equates and alcoholic extract of MC before MTX administration) also showed some notable histopathological changes including disorganization of seminiferous tubules and tubular vacuolation. Conclusion: When comparing the control group, examination of testes with H&E staining showed that pre-treatment with Matricaria Chamomile did not affect MTX-induced testicular damage.
Evaluation of the Effect of Ciprofloxacin on some Cytokines in Mice
Authors: Aqeel H. Atallah  , Nadia N. H. AL Masaoodi  , Khamael H. Obaid
Published: November 2022

The purpose of this study is to see if therapy with Ciprofloxacin (80 mg/kg body weight) for 3, 7, or 14 days has any influence on the levels of (Cytokines - 2, 4, 6, 10) in albino mice. The albino mice were put into four equal groups for the investigation. G. I: - The animals in this group were not given any material (control). G. II: - The animals in this group were given ciprofloxacin (80 mg/100 g body weight) (Dosage one per day Orally) for three days. G. III: - The animals in this group were given ciprofloxacin (80 mg/100 g body weight) (Dosage one per day Orally) for seven days. G. IV: - For 14 days, animals in this group were given ciprofloxacin (80 mg/100 g body weight) (Dosage one per day Orally). The results show that ciprofloxacin greatly increased Cytokines - 10 (especially after 14 days of therapy) (p<0.01), as well as Cytokines - 2, 6 (p<0.01), whereas Cytokines - 4 greatly decreased (P<0.05).
Impact Of Clinical Pharmacist Intervention On Quality Of Life And Adherence To Drugs Using Sf-36 Score And Morisky Scale In Patients in Patients With Heart Failure In Azadi Teaching Hospital
Authors: Intisar Ahmed Yusif
Published: November 2022

Background: Heart failure affecting a wide variety of population, causing high morbidity and mortality with high cost over a year, hospital based clinical pharmacist has an important role in management of patients with heart failure at level of drug monitoring, compliance, adherence to drugs and improving quality of life.Aims of The Study: evaluation of the role of clinical pharmacist intervention in management, monitoring of drug therapy, compliance, adherence and improving quality of life in patients with Heart failure.Methods: 100 patients involved in the study divided into two groups in this case-control comparison study 50 patients managed by MDT without participant of clinical pharmacist and the second 50 patients managed with MDT involving clinical pharmacist intervention using SF-36 score and Morisky scale.Results: Results showed that there is a significant increase in EF% from (35.3±1.8) % to (43.3±1.9) % with a P-value of (0.001)Conclusion: Clinical pharmacist intervention has a vital role in management of patients with Heart failure at a level of improving adherence, compliance, quality of life and as well as improving EF% of patients.
Correlation of the Interlukein-8 with Breast Cancer Patients in Iraqi Woman’s
Authors: Ahmed Khidher Hamza AL-Aflwky  , Orass Madhi Shaheed
Published: November 2022

Almost one-third of all female malignancies recorded in Iraq's most recent Iraqi Cancer Registry are breast cancers, making it the most common kind among women. With an anticipated 9.6 million deaths due to cancer in 2018, it is the second largest cause of death worldwide. One out of every six people who die in the world does so as a result of cancer. In low- and middle-income nations, cancer kills more than 70 percent of the population. Methods: This study include 49 samples patients and 40 samples (control group) which collection by draw of blood by gel tube and also the specimens were used centrifuge to get serum to measuring the interlukein-8 level by ELISA technique to both groups (patients, control). Results: measured IL-8 levels by ELISA technique and the results were referred to raise in IL-8 levels of BC females for serum samples compared with control group (healthy women). The cutoff value of serum IL-8 was >26.73 with good sensitivity, specificity and accuracy level respectively (73.47 %, 75 % and 72.0 %). The serum level of IL-8 was significantly higher in breast cancer group in comparison with control group, 36.69 (27.39) fold change versus 20.55 (13.83) fold change, respectively (p < 0.001). Conclusion: This study has found that the investigated interlukein-8 levels were associated with moderate to high grade carcinoma, this study may clarify that IL-8 along very important predictive and diagnostic marker for breast cancer and treatment responsiveness.
Evaluation of Interleukin-6 and Interleukin-10 in Patients with Urinary Tract Infection
Authors: Ahmed Hadi Dakheel  , Aseel Zghair Saadoon  , Ahmed abbas sahib
Published: November 2022

Background: Urinary tract infection (UTIs) are considered to be the most common infections in humans.Aims: this study aimed to evaluate the immune status of the patients with UTI by studying of (IL-6 and IL-10).Subjects and Methods: A total of 49 UTI patients infected with gram –ve bacteria and 25 healthy controls were enrolled in this study. Urine samples from UTI cases was collected in AL-Imam AL-Hussain teaching hospital in Thi- Qar province, during the period from February 2014 to July 2014. Urinary isolates were identified by conventional methods.3 ml were collected in plastic tube and then centrifuged at 3000 round per minute (rpm) for 5 min to obtain sera. And after the serum sample were collected they were divided into two apendroff tubes and stored in deep freeze at – 20º C until performing IL-6 and IL-10. (Lewis et al., 2006).Results: Patients with E. coli infection accounted for 26 (53.06%); other culture results were as follows: 7 (14.29 %) patients had K. pneumonia, 9 (18.37%) patients had P. aerogenosa, 4 (8.16%) had Proteus and 3 (6.12%) patients had K.oxytoca. Measure levels of serum IL-6 and IL-10 for study group against control group, which is showed a significant increase (P ≤ 0.01) in the levels of interleukins (IL-6, IL-10) in all serum patients compared to the control group.Conclusion: E- coli was most common causative agent in UTI, The high rate concentration of IL-6 and IL-10 in patients with UTI compared with the healthy control group. This refers to the injury for their role in the immune response.
Physical growth of Natural Soils Contamination and their metamorphosis of Mineralogical soils in vermiculite
Authors: Sreeram, V  , V D N Kumar Abbaraju  , Giriprasad Gorumutchu  , Kishore. V.N.V  , Avinash Rai Kola
Published: November 2022

This present work established the consequences of acidic and alkaline pore fluids over swell performance to inclusive soil. Observing the behaviour for transformations to various soils alkalis contaminate those is much needed to identify unique mineralogy and morphology variations. Authors are well concentrated on the effect of interactions of alkali over soils with increasing strength to a definite period along with an increase in interaction period to specified strength. A total of three different forces for sulphuric acid and potassium hydroxide were utilised as pore fluids for understanding the influence of variable strengths over the swell action of the soil. In contrast, their swelling decreased in the initial stage at a lower strength of sulphuric acid, later enhanced with an increase in solution strength. Two different vermiculite (magnesium-aluminium-iron silicate) soils were used as Diopside and tremolite. These are interacted by various strengths (0.5N, 0.1N, 2N, and 4N) of potassium hydroxide solutions within 9, 32, and 98days. Complexity in swell variations in contaminated soil is identified accurately by investigating with the help of X-ray diffraction, SEM, and Energy dispersive analysis of X-ray at the end of an interaction. Artificially contaminated samples are subjected to research using various instruments and finally concluded with SEM to mineralogical and their diagnosis variations. Keywords: Vermiculite, Metamorphosis, SEM, Dispersive analysis of Energy.
A randomised clinico-microbial trial evaluated the use of ozone as a supplement to scaling and root planing in the treatment of chronic periodontitis
Authors: Ratika Shrivastava  , Aishwarya Singh  , Abhilasha Bhawalkar  , Ragini Motwani  , Rahul Bachwani  , Sujith Kumar Palleti
Published: November 2022

Background and objectives: Controlling mechanical plaque is a crucial component of periodontal treatment. In the current research, the effectiveness of using ozone water irrigation in addition to scale and root planing to treat generalised chronic periodontitis was assessed.Materials and methods: After scaling and root planing, the twenty-four chronic periodontitis patients chosen for the research were randomly assigned to Group A or Group B, getting irrigation with ozone water or distilled water, respectively. To assess the "red complex" periodontal pathogens, subgingival plaque was taken from the chosen investigational teeth and examined using the BANA-ZymeTM Processor. At baseline, 14 days, 21 days, and 2 months, the clinical and microbiological data were noted.Results: At the baseline, Group A and Group B's mean probing pocket depth scores were 6.833 1.193 and 7.833 1.276, respectively; on Day 14, they were 6.616 1.403 and 7.083 1.378; on Day 21, they were 5.166 0.937 and 6.083 1.443; and on Month 2, they were 4.500 0.797 and 5.166 1.029. In Group A, 9 samples at the second month showed BANA negativity, 3 samples showed BANA positivity, and in Group B, 12 samples at the second month showed BANA negativity, 0 samples showed BANA positivity. In both groups, the microbiological study revealed a decrease in periodontal infections.Conclusion: An effective complement to scaling and root planing in the treatment of chronic periodontitis, subgingival ozonated water irrigation has shown significant improvement in both clinical and microbiological indices.
QUALITY OF STEAM BROWNIES AS A FUNCTIONAL FOOD FOR PREGNANT ANEMIA IN PREGNANT WOMEN IN STUNTING PREVENTION
Authors: Nur Riska  , Rusilanti  , Mariani  , Safira Salsabila
Published: November 2022

Aim: This study aims to study and analyze the effect of beet flour substitution on manufacturing steamed brownies on the physical quality.Material and Methods: This research was conducted at the Pastry and Bakery Processing Laboratory of the Culinary Education Study Program, State University of Jakarta. The time of research starts from July 2021 to June 2022. The method used in this study is experimental. The research samples used were steamed brownies with beet flour substitution of as much as 35%, 45%, and 55%, then tested three times.Results: Based on the results of the statistical hypothesis test, the physical quality test using the ANOVA test showed that the aspects of swell ability, stability, and crumb morphology had no significant effect or difference in the substitution of beetroot flour as much as 35%, 45%, and 55% in the manufacture of steamed brownies.Conclusion: The conclusion of this study is to recommend steamed brownies with 55% beet flour substitution to be developed to optimize the utilization of beetroot flour as a nutritional value enhancer.
Evaluation of prevalence of dental implants failures with various risk factors: A 15 years retrospective study
Authors: Mohd Atheequr Rehman Pyare  , Asmita Yogesh Lade  , Nidhi Manhas  , Davis Nadakkavukaran  , Madhvika Patidar  , Parul Jain  , Richa Goel
Published: November 2022

Background: Dental implants must be positioned in areas with a high rate of success. The current retrospective study's objective was to identify risk variables that might have an impact on dental implant success rates as well as the prevalence of dental implant failure among patients who had their implants placed more than 10 years ago.Materials & Methods: The current retrospective analysis involved 1230 dental implants placed in 728 patients of both sexes. The implant's length, diameter, placement, and bone quality were all noted. Risk factors were noted, including smoking behaviour, diabetes history, hypertension, etc.Results: Dental implants were inserted in 415 male patients (764, or 62%) and 313 female patients (466, or 38%). Dental implants failed in 81 (10.6%) male patients and 34 (7.3%) female patients. Statistically, it was significant. Greatest failure of dental implant was observed with lengths of 10 mm in 42 cases (17%), 10–11.5 mm in 30 cases (9%), and >11.5 mm in 54 cases (8.2%). The variation was substantial.Greatest failure of dental implant was observed with diameters of 3.75 mm or below (12.4%), 3.75 mm to 4.5 mm (8.1%), and > 4.5 mm (7.5%). It was determined that the difference was significant (P 0.05). Type IV bone had the highest rate of dental implant failure (16.8%), subsequently type three (9.4%), type two (8.2%), and type one bone (6.4%). The variation was determined to be important (P 0.05). Smoking (41%) and CVDs (35.7%), diabetes (30.8%), and hypertension (18.8%) were the two factors that caused the most dental implant failures, while healthy individuals had the lowest failure rate (2.9%). ANOVA analysis revealed a variation among implant failure depending on risk factors that was significantly different (P 0.05).Conclusion: Researchers discovered that dental implants have a high rate of success. Dental implants with a length of less than 10.0 mm, a diameter of less than 3.75 mm, and patients with diabetes and type four bone had the highest failure rates.
AN IN VITRO COMPARISION OF BOND STRENGTH OF PRECOATED AND UNCOATED BRACKETS USING SELF ETCHING PRIMER
Authors: Debojyoti Roy  , Arunima Goswami  , Heeralal Chokotiya
Published: November 2022

Aim: To test the hypothesis that there is no significant difference in the shear bond strength and the adhesive remnant on the tooth after debonding between precoated and uncoated brackets using a self etching primer.Materials and Methods: Adhesive Pre Coated Plus brackets, Uncoated brackets, Transbond XT adhesive and Transbond Plus self etching primer (TPSEP) were used in this study. The brackets were bonded to intact human premolar teeth. All the samples were divided into two groups --Group 1 (Uncoated brackets + Transbond Self Etching Primer + Transbond XT) & Group 2 (Adhesive Precoated Brackets + Transbond Self Etching Primer). Universal Testing Machine was used for calculating the shear bond strength of all samples. Image analysis equipment was used to measure the adhesive remnant on each tooth after debonding. Scanning Electron Microscope was used for this purpose.Results: Group 1 (Uncoated brackets + Transbond Self Etching Primer + Transbond XT) & Group 2 (Adhesive Precoated Brackets + Transbond Self Etching Primer) had nearly equal mean shear bond strength which is 8.86 +2.14 Mpa for precoated while 9.08 + 2.76 Mpa for the uncoated group. Statistically both the groups have almost same shear bond strength and significant difference was absent. In percentage of adhesive remnant also statistical difference between group 1 & group 2 was absent.Conclusion: There was no significant difference in the shear bond strength and the adhesive remnant on the tooth after debonding between precoated and uncoated brackets using a self etching primer.
“Evaluate the effectiveness of Clinical Problem Based Learning regarding the care of the patient with Diabetic foot among I year B.Sc. Nursing students of selected Colleges of Nursing in Kasaragod, Kerala.”
Authors: Ambily V V  , Padmakumar S  , Manjunath Beth  , Prasanna Deshpande
Published: November 2022

BACKGROUND: A Quasi-experimental study was undertaken to evaluate the effectiveness of Clinical Problem Based Learning (CPBL) in the care of the patient with Diabetic foot among I year BSc. Nursing students in selected colleges of Nursing in Kasaragod, Kerala.AIM: The objectives of this study were to assess the knowledge of I year B.Sc. Nursing students regarding the care of patients with Diabetic feet in experimental and control groups, evaluate the effectiveness of CPBL in the care of the patient with Diabetic feet in the experimental group, compare the post-test knowledge scores in the experimental group and control group and find out the association between the pretest level of knowledge of I year B.Sc. Nursing students regarding the care of patients with Diabetic foot with their selected variables.METHODS: The study was conducted at selected Colleges of Nursing in Kasaragod.The research approach for the study was an evaluative, pretest-posttest control group design. The sampling technique used for the study was purposive, and the research tool was the Structured Knowledge Questionnaire.RESULTS: The result of the study showed that the mean post-test knowledge score (22± 1.71) was higher than the pre-test knowledge score (12± 2.50). The calculated ‘t’ value of 13.38 was greater than the table value (t39=2.09) at a 0.05 level of significance.It was also found that there was no association between the pretest level of knowledge and selected variables.CONCLUSION: Thus, it was proved that Clinical Problem Based Learning was an effective teaching method for creating awareness regarding the care of the patient with a Diabetic foot.
"A search to evaluate the efficacy of an information booklet on the knowledge and practice relating to lifestyle modifications among patients with coronary artery disease at selected hospitals of Surat, Gujarat"
Authors: Manjunath Beth  , Padmakumar S  , Prasanna Deshpande  , Ambily V V
Published: November 2022

The blood flow to the heart is impacted by ischemic heart disease, sometimes referred to as coronary artery disease. As a result of the buildup of plaque formation, the walls of blood arteries become constricted or clogged. The heart's musculature needs oxygen and nourishment to operate properly, which is decreased as a result. This might eventually lead to the abrupt deprivation of blood flow to a section of the heart, which would kill that section’s heart attack via damaging cardiac tissue. Any cardiac abnormality instantly impacts the flow of oxygen to the brain, kidneys, and other essential organs since the heart are the pump that delivers oxygenated blood to the other vital organs. The tissue inside these organs is impacted as a result to die, which ultimately causes failure or death. The top factor of death in several nations throughout the world is ischemic heart disease. The aim and objective of the study is the usefulness of a booklet providing advice on lifestyle changes for people with coronary artery disease. This study's conceptual model is based on "Imogene King's goal achievement theory". This study aimed to gauge people's understanding of lifestyle changes for cardiac patients. The quantitative research technique was used in this investigation. Pre- and post-testing in one group and preliminary research design were used. Techniques of non-probability random sampling were employed to choose the samples. The sample size was 60 in total. We employed both descriptive and inferential statistics in the data examination. After administering the information packet, the study's findings revealed a considerable increase in knowledge and practice during the post-test. The information booklet was a useful tool that raised patients' knowledge and practices to the desired level.
"Research to determine the likelihood that hospitalized patients may fall and the preventative measures used in the chosen hospitals in the state of Gujarat"
Authors: Manjunath Beth  , Ambily V V  , Padmakumar S  , Prasanna Deshpande
Published: November 2022

Patient falls are the most common patient safety accidents in hospitals, which have an effect on the patient's rehabilitation and extend the patient's stay. By screening and evaluating patients, nurses and other healthcare professionals can determine who is at risk of falling. The cost of injuries brought on by falls is considerable. The average cost to the health system in the Republic of Finland and Australia for a fall injury among those 65 and older is 3611 and 1049 USD, respectively. The conceptual framework used in this inquiry was built on the modified General System model.A survey design was employed in conjunction with a quantitative research technique. The Purposive non-probability sampling approach is accustomed to choosing the instance. 110 nurses and 121 patients from 4 hospitals were chosen for the research. Out of 121 patients tested, 9 (7.44 per cent) were found to be at high risk for falls, 22 (18.18 per cent) were found to be at moderate risk, and the remainder (74.38 per cent) were found to pose little danger.The research remained conducted to switch which hospitalized patients were more at risk for falling and to determine the preventive measures implemented in particular Surat hospitals. The study's goals were accomplished by the researcher.
Find out the effect of Hot application on the prevention of Thrombophlebitis among patients with Peripheral Intra Venous Cannula in a selected hospital at Kasaragod, Kerala
Authors: Padmakumar S  , Ambily V V  , Prasanna Deshpande  , Manjunath Beth
Published: November 2022

BACKGROUND: An evaluative quasi-experimental study was undertaken to find out the effect of Hot application on the prevention of Thrombophlebitis among patients with Peripheral Intra Venous Cannula (PIVC) in a selected hospital in Kasaragod, Kerala.AIMS AND OBJECTIVES: The objectives of this study were to find out the occurrence of Thrombophlebitis among patients with PIVC in the Experimental group and Control group by using the Modified Thrombophlebitis Scale, to compare the occurrence of Thrombophlebitis in the Experimental group and Control group and to find out the association between the occurrence of Thrombophlebitis and selected variables.METHODOLGY: The conceptual framework of the study was based on Lydia Hall’s Core, Care and Cure model. The research tool was the Modified Thrombophlebitis Scale. The study was conducted in Malik Deenar Charitable Hospital, Kasaragod in January 2013. By purposive sampling technique, 60 samples that met the inclusion criteria were selected.RESULTS: Results of the study showed that the occurrence of Thrombophlebitis in the Experimental group after Hot application was 6.67% and, in the Control, the group was 93.33%. The calculated ‘Z’ test score (6.7) was higher than the table value (p=1.96) at a 0.05 level of significance. There was no significant association between the occurrence of Thrombophlebitis and selected variables except for the number of Intra Venous (IV) medications administered. There was an evident difference in the occurrence of Thrombophlebitis in the Experimental group and Control group.CONCLUSION: Thus, it was proved that the Hot application was effective in the prevention of Thrombophlebitis among patients with PIVC.
Research to evaluate the efficiency of the structured teaching programme in terms of knowledge on prevention of sexually transmitted diseases among college students at chosen institutions in Dharwad, Karnataka, INDIA
Authors: Prasanna Deshpande  , Padmakumar S  , Manjunath Beth  , Ambily V V
Published: November 2022

Sex is a natural human function that may be used to express love and other strong emotions and does in fact enable reproduction. However, having a sexual relationship might have unforeseen or detrimental effects. Unintentional pregnancy and sexually transmitted illnesses, such as HIV infection, are two of the main possible health effects of sexual activity. Effective preventative efforts and a nationwide open discussion of these issues can significantly lessen these negative effects.
Quality of Life for anxiety Patients in Holy Kerbala City
Authors: Ali sabry al-yasari  , Ali Kareem Al-Juboori
Published: November 2022

Background: The quality of life concept has very important and remarkable today and its definition is surely complex. Quality of life is of great importance in disease outcomes and patient assessment. So quality of life has emerged as a crucial endpoint in lots of research of scientific and surgical interventions.Method: A quantitative descriptive study, the study was completed with 52 patients with anxiety disorder to find out the quality of life for the them.Result: The results showed unacceptable level of quality of life of anxiety patient was 44.04. with reverse impact of anxiety illness upon quality of life.Conclusion: There is unacceptable quality of life for anxiety patients, and the anxiety has a greater negative impact on quality of life.Recommendations: Attempting to find out an effective solutions to reduce anxiety in patients to improve the quality of life, such as activate the group therapy and activate the nurse role in the therapy.
A STUDY TO EVALUATE THE EFFECTIVENESS OF ANULOM-VILOM TECHNIQUES ON REDUCTION OF ANXIETY AMONG PATIENTS WITH DIABETES MELLITUS ADMITTED IN SELECTED HOSPITAL DHARWAD
Authors: Hanamanth. S. EkAbote  , Renuka.R. Bagewadi  , Rangappa.S. Ashi
Published: November 2022

Anlom Vilom is one of the most effective pranayama. It modulates anxiety responses to and in turn reduces the complex health problems arising due to anxiety. Anlom vilom is found useful in diabetes as alternate nostril breathing has calming effects on the nervous system, facilitating homeostasis. Knowing the background, the study undertaken to evaluate the effectiveness of anlom-vilom techniques on reduction of anxiety among patients with diabetes mellitus admitted in selected hospital Dharwad.The objectives of the study are to:• Assess the level of anxiety among patients with type 2 diabetes.• Evaluate the effectiveness of Anlom-Vilom technique on reduction of anxiety among diabetes patients.• Find an association between pre-intervention mean level of anxiety among type 2 diabetes and selected demographic variable.Conceptual framework: selected for this study was based on modified Learning Bandura’s Theory. Methods: The Pre experimental with one group pre and post-test design was adopted for the present study. The sample consisted of 40 Type 2 diabetes patients selected by non-probability purposive sampling technique. The tool comprised of 2 section namely demographic Proforma and modified Beck anxiety scale and analyzed by using descriptive and inferential statistics appropriate to achieve set of objectives. Results: Maximum 15(37.5%) respondents belong to age between 40-50 years. Majority of the respondents 26(65%) of respondents were males .35 (87.5%) of respondents were married. Maximum of 16(40%) belonged to primary schooling. Majority of 36(90%) had joint family .Maximum of 11(27.5%) were skilled workers. Majority 17(42.5%) had 5000 Rs monthly income and majority 21(52.5%) were on mixed diet. Interpretation and conclusion: Based on the findings of the study anulom vilom technique was effective on reduction of anxiety among patients with type 2 diabetes mellitus.
STUDY ON TALENT MANAGEMENT PRACTICES IN PHARMA SECTOR WITH FOCUS ON "EMPLOYEE RETENTION”
Authors: Thilagham K T  , Malini.T.N  , P.Tirumala  , Auadhati Datta  , Gauri Singh Bhadauria  , Priyanka Agarwal
Published: November 2022

The pharmaceutical sector in India currently holds a dominant position in the market for generic pharmaceuticals around the world. The industry is characterized by a one-of-a-kind mixture of both opportunities and limitations. It has achieved the global excellence standards in the mass manufacture of high-quality branded generics, which was driven by its capabilities in formulations that are of world-class standard. This achievement was driven by the fact that it has attained the mass manufacturing of branded generics. These are the result of prolonged expenditures in infrastructure and research & development on the part of industry leaders, who were also responsible for their creation. In addition, there are a huge number of small and medium-sized firms, which contributes to the industry's highly fragmented nature. The purpose of this study are to investigate the factors that contribute to employee turnover in the Indian context generally and in the pharmaceutical industry and to outline a deeper understanding of the strategies that are used for talent management and employee retention in the pharmaceutical industry.The pharmaceutical industry in India has the greatest employee turnover rate, and each industrial unit within the sector uses a unique combination of criteria and procedures to choose its talent, deliver its training, and take its various capacity-building steps. There is also a significant financial reward connected with work performance in the form of salaries and other benefits. Even with all of the necessary efforts, the retention of highly skilled employees to grass root functionaries continues to be a repeated pattern; nevertheless, the causes and impact of this phenomenon are not disclosed to aid the companies. As a consequence of this, the collecting of primary material became obligatory in order to investigate the subject in depth and evaluate the impact of the attrition problem. The secondary sources of information that were utilised in the research study have been appropriately acknowledged, and the primary data that the research scholar gathered, organized, and assessed on their own have been appropriately analyzed. The pharmaceutical sector relies on an extensive network of medical representatives, each of whom is individually tasked with driving sales of their company's wares in the marketplace. The grass-roots functionaries encompass a vast number of individuals in this category. The suggestions for lowering the rate of employee turnover are, for the most part, based on the field response from the respondents as well as management from the firms. The study was conducted in Chennai city during the month of January 2022. The primary data was collected using Google forms.
A STUDY ON EMPLOYEES JOB SATISFACTION IN SELECTED PHARMACEUTICAL INDUSTRIES
Authors: Somanchi Hari Krishna  , Ravindra R Kaikini  , Senthil K Nathan  , K.M.Priya  , Sanjay Kumar  , Gitanjali Singh
Published: November 2022

The advancement of the economy is significantly impacted by the activities of the pharmaceutical industry. This investigation's objective is to ascertain the degree to which workers at various drug companies are content with their jobs and the role that they play in the company. The major emphasis of this inquiry is on the relevance of the phrase "occupation fulfilment factors" and the influence that these aspects have on the overall sense of job satisfaction experienced by representatives. The pharmaceutical industry's representatives have progressed to the advantageous stage of the summative task fulfilment procedure. The current evaluation gives an update on the level of job satisfaction that is now held by representatives of various pharmacy organisations and analyses some of the issues that have come up as a result. The aim of the study are to examine the Profile of the sample respondents in examined area and to determine the elements that impact employee work satisfaction .A descriptive research design combined with a survey methodology was used. For the aim of this study, the researcher has drawn from the primary and the secondary bodies of information. The secondary data were gathered from a variety of resources, including books, periodicals, articles, research projects, and websites. The period of the data collection was done through the Google forms during September 2021. Convenient sampling technique was applied to collect the primary data from 120 sample respondents As a direct result of the continued expansion that the pharmaceutical industry in India is experiencing at the present time, research has primarily begun to investigate the significance of a number of factors, including compensation and advancement opportunities, working climate and conditions, employer stability, worker relationship, and reasonableness in terms of work fulfilment.
REVIEW OF LITERATURE ON BUSINESS ETHICS PRACTICES IN PHARMACEUTICAL COMPANIES IN INDIA
Authors: B.Nagarjuna  , V.Ambika  , U.R.Rakshith  , Gitanjali Singh  , E.Devashree  , A.Sulthan Mohideen
Published: November 2022

Ethics is the practice of philosophy. It is the branch of philosophy concerned with determining what is good or evil, right or wrong. Ethics is the topic of everyday life, which is regulated by whether something is good or bad and based on the ideas of morality, welfare, Rights & duties, justice, equality, liberty, and virtue. Ethics, economics, and law are so interdependent that it might be difficult to choose which should be cherished the most. Ethics include not just why something is done, but also how it is done and who did it. Topical concerns include corporate Social Responsibility and Corporate Governance. The findings of the research will provide practitioners and policymakers with assistance in educating themselves about issues that have an immediate need to be resolved, and it will shed some light on issues that should be prioritized in order to concentrate on and design strategies for effectively gaining a competitive edge. The pharmaceutical business is significantly reliant on Research & Development for the development of new products and its expansion. Nonetheless, fundamental research (discovering new compounds) is a time-consuming and costly endeavor, and is thus dominated by giant multinational corporations.
THE EFFECT OF SERVICE QUALITY ON PATIENT LOYALTY MEDIATED BY PATIENT SATISFACTION
Authors: Suja Sundram  , Sunil E. Tambvekar  , S.Sekar  , Ghada-elkady  , Shiv Kant Tiwari  , R.Gopinathan
Published: November 2022

Healthcare professionals often strive to satisfy their patients by addressing their healthcare issues. Patient satisfaction is a crucial component in evaluating the quality of healthcare because it shows how well the staff is achieving the patients' goals. It has a significant impact on patients' expectations. The hospital sector must attain service quality standards that include accurate and precise outcomes of medical examinations, as well as polite and helpful treatment. The level of patient satisfaction affected many different areas of health care organisations. Customer loyalty was thought to be mostly influenced by the caliber of the services provided. Patients who experience such contentment will feel at ease and develop a favourable opinion of the caliber of the services. A key factor in achieving patient satisfaction was service quality. As a result, the patient felt that hospital services deserved to be at the top, leading him to pledge his commitment by refusing to use hospitals run by other companies.
A STUDY ON EMPLOYER BRANDING FOR HOSPITALS WITH REFERENCE TO COIMBATORE
Authors: Balakrishnan.S  , R.Saranya  , M.Suryakumar  , Ankush Sharma  , Karthika M  , R.Gopinathan
Published: November 2022

Hospitals are an unavoidable sector in the modern world, which is pushed by technology, and they are the sector that displays the standing of a country on an international level. Every country's ability to deliver high-quality medical care is an indication of its level of progress toward a brighter future. Therefore, "Employer Branding" for hospitals is something that must be done in order to ensure both higher quality services and continued growth in the health care industry. The technique of building a positive employer brand has shown to be valuable for many kinds of businesses, including hospitals. This, in turn, leads to a means for them to keep their brilliant personnel, which is the fundamental need that any hospital must fulfil in order to achieve a competitive edge. The company has become more competitive as a result of the dynamic development that has taken place in today's competitive globe. In order to thrive in the cutthroat competition brought on by globalization, a business has to find a way to differentiate itself from its competitors and secure a competitive edge. It has to be proactive in order to deal with the shifting circumstances. In this particular case, the organization's human resources are serving as the primary propellants behind its expansion. The success of an organisation is dependent on the quality of work that is accomplished by the workforce. Human resources are the ones who decide, implement, and manage the activities inside a company because of their skills, aptitudes, and attitudes. They are the ones who are the drivers of the organisation. Now is the moment for the organisation to make the move that will put them ahead of their rivals and place them in first place. In light of these circumstances, talent management has emerged as a key instrument for the development of organisations, which should be matched with the growth of individuals.