Design of The Middle East African Registry for Women's CardioVascular Disease (MEA-WCVD) (Preprint)
Authors: Charfeddine Salma , Abid Leila , Chenik Sarra , Ghrab Aymen , Haddar Oussama , Ben Krayen Iheb , Boudiche Selim , Touati Haithem , Ayedi Oumaima , Ammar Mohamed Amine , Ben Halima Manel , Ben Ayed Houssem , Brahim Asma , ElAyech Faten , Thabet Houssem , Mahfoudhi Houaida , Jabloun Taha Yessine , Ayadi Yasmine , Ayadi Alaeddine , Romdhani Ghassen , Gargouri Hassen , Zidi Oumayma , Guedri Mohamed Ali , Tlili Rami , Trabelsi Bechir , Hammami Selim , Othmen Rim , Antit Saoussen , Saidane Syrine , Dardour Sirine , Iddir Skander , Kharrat Elmahdi , Cheikhrouhou Anis , Derwich Mohamed , Mrabet Amal , Lassoued Taha , Rekik Emna , Gmiha Sahar , Laribi Niez , Lamine Hakim , Triki Zied , Ayari Samir , Boujelbene Fatma , Boughzela Essia , Rekik Hajer , Ben Ameur Ines , Abid Syrine , Oueghlani Khalil , Haggui Abddayem , Ben Halima Afef , Ouechtati Wejdene , Bennour Emna , Hammami Rania , Jabeur Mariem , Zairi Ihsen , Drissa Mariem , Addad Faouzi , Milouchi Sami , Mourali Mohamed Sami , Ben Slima Hedi , Bezdah Leila , Neffati Elyes , Ben Ameur Youssef , Kraiem Sondos , Kachboura Salem , Kammoun Ikram , Zakhama Lilia , lbn Hadj Amor Hassen , Ben Hamda Khaldoun , Messoudi Yosra , Ben Hlima Nejah , Dahmani Rana , Gamra Habib , Ibn Elhadj Zied , Denguir Hichem , Ghorbel Chayma , Mechri Nizar , Ernez Hajri Samia , Mebazaa Alexandre , Ben Dhaou Fedi , Trigui Maroua , Fehri Wafa , Abdessalem Salem 
Published: February 2025

BACKGROUND

The escalating incidence of cardiovascular disease (CVD) in the general population, particularly among women, has resulted in increased morbidity and mortality in the Middle East and African (MEA) Regions. Despite this concerning tendency, women remain significantly underrepresented in cardiovascular research, with no large-scale prospective multicenter trials reflecting national data published to date. To address this gap, we initiated the "Women CardioVascular Disease Middle East African Registry (MEA-WCVD)" to establish a comprehensive database on the contemporary epidemiological profile and management of Heart Failure (HF), Atrial fibrillation (AF), ischemic heart disease (IHD) and Valvular Heart disease (VHD) in women.

OBJECTIVE

This study aims to compare the management of cardiovascular diseases in women and men in a MEA countries sample, according to the current practice guidelines and encompass the identification of gender-based disparities, specifically examining healthcare insurance, income, and access to healthcare services.

METHODS

This prospective observational study involves a one-shot visit where patients diagnosed with HF, AF, IHD, or VHD provide informed consent, and their data are collected in a centralized certified database. The registry spans 75 days, with plans for an extended protocol to assess 1-year clinical outcomes.

RESULTS

The study's findings, expected at the conclusion, will include a comprehensive evaluation of the demographic profile and care management practices for the most prevalent cardiovascular diseases in women worldwide, aligned with current guidelines. The MEA-WCVD registry is anticipated to become the largest database for Middle East African patients monitored for HF, AF, IHD, and VHD.

CONCLUSIONS

The MEA-WCVD registry will provide unique and necessary data on the management and outcomes of the most common CV diseases (AF, HF, IHD and VHD) while comparing standard care management in women to men in MEA regions.
This study will yield the largest contemporary cohort of patients with cardiovascular diseases in MEA countries and would provide valuable answers about real-world cardio-vascular clinical epidemiology and management.