bluuebunny/crossref_metadata_2025 huggingface dataset:
Intersign Glove: A Communication Interface for the Aid of Deaf and Mute Community
Authors: Finny Theophorus Gaddala , Singh Balwant
Published: June 2024

Intersign Glove " is a groundbreaking innovation designed to address the communication barriers faced by the deaf and mute community. With the aim of revolutionizing traditional methods of communication, this paper introduces an innovative approach that utilizes gesture recognition technology to interpret Indian Sign Language (ISL) in real-time. The paper endeavors to eliminate the dependency on sign language interpreters by creating an embedded system comprising both hardware and software components. By leveraging advanced sensors strategically placed on a glove, the system captures intricate gesture parameters and translates them into code for computation. This code is then processed by a microcontroller board integrated into the glove, which generates corresponding speech output through an attached speaker, facilitating seamless communication between the user and non-sign language speakers. The wearable nature of the device ensures portability and ease of use, empowering individuals with hearing and speech impairments to communicate effectively in various social settings. Furthermore, by bridging the communication gap between the deaf and mute community and the wider population, this paper opens up new opportunities for inclusion and collaboration. "Intersign Glove" represents a significant advancement in assistive technology, promising to enhance the quality of life for individuals with hearing and speech disabilities while fostering greater understanding and integration within society.
Enhancing epidemic management: agent-based simulation and remote diagnosis
Authors: Abdelaziz Djamel-Eddine , Kadri Ouahab
Published: June 2024

The objective of this work is to analyze the spread of contagious diseases using a multi-agent simulation and a remote diagnostic system. The simulation is carried out using information on patients and the environment. The novelty of this work lies in proposing a new agent architecture that combines both independent and random behavior to better simulate individuals in the real world. We have proposed two communication methods between the agents either by a direct exchange of messages or by placing objects in a common space. The various simulations have enabled the prediction of the time required to transition from a normal state to a critical condition. A comparative study between the proposed diagnostic method and alternative techniques has demonstrated its superiority in accuracy.
GLA:D to Be Walking Better: Change in Self-Reported Difficulty Walking After Exercise Therapy and Education in Persons With Knee Osteoarthritis
Authors: King Lauren K. , Young James J. , Grønne Dorte T. , Bricca Alessio , Roos Ewa M. , Skou Søren T. , Hawker Gillian A.
Published: June 2024

Objective

Difficulty walking is a primary reason that individuals with knee osteoarthritis (OA) seek care. We examined the change in self-reported difficulty walking after participating in the Good Life With Osteoarthritis in Denmark (GLA:D) 8-week education and exercise program and assessed patient factors associated with improvement in difficulty walking.

Methods

This was a registry-based cohort study of individuals in Denmark with knee OA who enrolled in GLA:D. Assessments were administered at baseline, program completion (~3 months), and 12 months. Our prespecified primary outcome was change in self-reported difficulty walking assessed using the EuroQol 5-dimension 5-level walking item. Exposures included sociodemographic factors, measures of OA illness severity, comorbidities, and psychological factors. In those with baseline moderate/severe difficulty walking, using multivariable regression analysis, we assessed the relationship between exposures of interest and improvement to no/slight difficulty walking.

Results

We included 5262 participants. Of 2178 (41.4%) individuals with baseline moderate/severe difficulty walking, 51.4% and 58.3% reported no/slight difficulty walking at 3 and 12 months, respectively. Greater self-efficacy, younger age, female sex, lower BMI, less intense knee pain, and better function at baseline were associated with greater likelihood of improvement in difficulty walking, whereas severe difficulty walking at baseline and back pain intensity were associated with decreased likelihood of improvement.

Conclusion

More than half of those with baseline difficulty walking experienced substantial improvement after completing GLA:D and this improvement was maintained at 12 months. Several patient factors were associated with the outcome, suggesting that some individuals may require additional support and extended treatment.
Clinical Validation of Digitally Acquired Clinical Data and Machine Learning Models for Remote Measurement of Psoriasis and Psoriatic Arthritis: A Proof-of-Concept Study
Authors: Webster Dan E. , Haberman Rebecca H. , Perez-Chada Lourdes M. , Tummalacherla Meghasyam , Tediarjo Aryton , Yadav Vijay , Neto Elias Chaibub , MacDuffie Woody , DePhillips Michael , Sieg Eric , Catron Sydney , Grant Carly , Francis Wynona , Nguyen Marina , Yussuff Muibat , Castillo Rochelle L. , Yan Di , Neimann Andrea L. , Reddy Soumya M. , Ogdie Alexis , Kolivras Athanassios , Kellen Michael R. , Mangravite Lara M. , Sieberts Solveig K. , Omberg Larsson , Merola Joseph F. , Scher Jose U.
Published: June 2024

Objective

Psoriatic disease remains underdiagnosed and undertreated. We developed and validated a suite of novel, sensor-based smartphone assessments (Psorcast app) that can be self-administered to measure cutaneous and musculoskeletal signs and symptoms of psoriatic disease.

Methods

Participants with psoriasis (PsO) or psoriatic arthritis (PsA) and healthy controls were recruited between June 5, 2019, and November 10, 2021, at 2 academic medical centers. Concordance and accuracy of digital measures and image-based machine learning models were compared to their analogous clinical measures from trained rheumatologists and dermatologists.

Results

Of 104 study participants, 51 (49%) were female and 53 (51%) were male, with a mean age of 42.3 years (SD 12.6). Seventy-nine (76%) participants had PsA, 16 (15.4%) had PsO, and 9 (8.7%) were healthy controls. Digital patient assessment of percent body surface area (BSA) affected with PsO demonstrated very strong concordance (Lin concordance correlation coefficient [CCC] 0.94 [95% CI 0.91-0.96]) with physician-assessed BSA. The in-clinic and remote target plaque physician global assessments showed fair-to-moderate concordance (CCCerythema0.72 [0.59-0.85]; CCCinduration0.72 [0.62-0.82]; CCCscaling0.60 [0.48-0.72]). Machine learning models of hand photos taken by patients accurately identified clinically diagnosed nail PsO with an accuracy of 0.76. The Digital Jar Open assessment categorized physician-assessed upper extremity involvement, considering joint tenderness or enthesitis (AUROC 0.68 [0.47-0.85]).

Conclusion

The Psorcast digital assessments achieved significant clinical validity, although they require further validation in larger cohorts before use in evidence-based medicine or clinical trial settings. The smartphone software and analysis pipelines from the Psorcast suite are open source and freely available.
Calcium Pyrophosphate Crystals in a Child With Wilson Disease: An Ominous Sign or Incidental Finding?
Authors: Bolivar-Wagers Sara , Shaheen Zachary R.
Published: June 2024

Calcium pyrophosphate dihydrate (CPPD) crystal deposition may cause acute arthritis (pseudogout), cartilage degeneration identified radiographically as chondrocalcinosis (CC), and other chronic degenerative joint changes in patients aged > 60 years. The few reported cases of CPPD disease in younger patients have been associated with underlying genetic or metabolic conditions.1,2
Long-Term Data on Efficacy and Safety of Selexipag for Digital Systemic Sclerosis Vasculopathy
Authors: Di Battista Marco , Della Rossa Alessandra , Mosca Marta
Published: June 2024

Objective

Raynaud phenomenon (RP) and digital ulcers (DUs) are the main signs of digital vasculopathy in systemic sclerosis (SSc). Selexipag is an oral prostacyclin agonist approved for SSc-related pulmonary arterial hypertension. Following our previous preliminary short-course report, we herein present long-term data on selexipag safety and efficacy in the treatment of SSc digital vasculopathy.

Methods

Selexipag was administered to patients with SSc with severe digital vasculopathy refractory or with contraindication to all other vasoactive therapies. Each subject was assessed at baseline and after 3, 6, and 12 months. Clinical outcomes related to RP and DUs were evaluated along with modified Rodnan skin score of the fingers. Digital perfusion was assessed by laser speckle contrast analysis (LASCA). Nailfold videocapillaroscopy (NVC) was also performed.

Results

Eight patients with SSc (63% female, mean age 50.1 years) received selexipag. After 12 months of treatment, RP was reported to significantly decrease in the number of daily episodes and mean duration (P< 0.001 andP= 0.01, respectively). All patients achieved a complete healing of their DUs (P= 0.03) within 6 months. A progressive reduction of fingers skin score was observed (P= 0.03). No structural changes of capillaries were noted on NVC. Conversely, LASCA revealed an important increase in total digital perfusion (P= 0.004) despite seasonal variability. The safety profile was consistent with that reported in the literature.

Conclusion

We observed a sustained efficacy of selexipag on SSc digital vasculopathy during 1 year of administration. Our promising results encourage the design of a new randomized controlled trial to evaluate the effect of selexipag on SSc digital vasculopathy.
Scientific method for assessing "Real Madrid DNA": merely a catchy journalistic term or reality?
Authors: Maza Adolfo
Published: June 2024

The purpose of this study was to evaluate whether the frequent references to "Real Madrid DNA", when a team comes from behind in the last minutes of a match, could be understood as merely a journalistic surrogate for truth or having simply degenerated into a catchy phrase without much meaning. We took, as a case study, clubs playing in the top division of the Spanish league between the 2010–2011 and 2021-2022 seasons, resulting in an unbalanced panel with 34 clubs that played at least one season in that category. As for the methodology, a variable was created to measure the percentage of times a club comes from behind in the last minutes of a match and explained using a model that included the economic power of the club, other match-specific variables, and fixed effects to assess whether a differentiating effect for Real Madrid (RM) was detected. Concerning empirical findings, it can be asserted that RM's undoubted ability to improve its results in the final stretch of matches comes mainly from money but also from something else hard to explain. Put differently, finding support to RM having something special, which we can refer to as its DNA. RM's fixed effect is not only positive and different from zero but also higher than any other team. Indeed, it differs from the remaining ones from a statistical point of view.
La mobilisation corporelle dans les projets de réinsertion
Authors: Maguy Jennifer
Published: June 2024

Depuis quelques années, les intervenants sociaux mobilisent le corps comme outil d’accompagnement social dans leurs projets de réinsertion. Le recours du corps au travers de dispositifs artistiques et/ou culturels permettrait aux bénéficiaires de susciter leur désir et leur engagement dans les projets, mais aussi de s’ouvrir et de se lier plus facilement aux autres. Cet article visera à comprendre, dans un premier temps, les raisons de cet intérêt pour le corps et de son inscription dans les pratiques professionnelles des intervenants sociaux et dans les suivis qu’ils proposent aux bénéficiaires, que nous pourrons mettre en parallèle avec certaines mutations dans le champ du travail social, relatives au traitement de la réinsertion. Puis, dans un second temps, nous tenterons de montrer que cet usage particulier du corps mobilisé et employé à la réinsertion sociale et/ou professionnelle conduirait à une activation sociale des bénéficiaires, visible au travers de l’apprentissage d’un ensemble de savoirs et de dispositions faites corps.
L’embourgeoisement, moteur du changement social en banlieue populaire au tournant du XXIe siècle
Authors: Clech Pauline
Published: June 2024

Depuis la désindustrialisation, la question du changement social en banlieue populaire alimente une abondante littérature sociologique. À la suite des recherches françaises récentes étudiant la dimension spatiale des rapports sociaux, cet article propose une clarification conceptuelle des catégories sociologiques pour analyser le changement social « par le haut » en banlieue populaire. À partir d’une analyse statistique et cartographique du changement social affectant l’espace de la première couronne parisienne au début du XXIe siècle, cet article invite à sortir du binarisme pour analyser les transformations sociales en cours, ainsi qu’à distinguer les processus de gentrification (mineur) et d’embourgeoisement (majeur). Ce faisant, l’article montre l’utilité d’articuler les théories du changement socio-spatial, des classes sociales et de la mobilité sociale, en combinant l’échelle métropolitaine, locale et individuelle. À une analyse classique de la morphologie sociale localisée, il articule celle des stratégies d’accumulation pour stabiliser la position de classe.
« La plaine est morte et la ville la mange » : l’urbanisation planétaire vue de l’arrière-pays rural de Rabat-Salé-Témara (Maroc)
Authors: Amarouche Maryame , Rousseau Max , Salik Kawtar
Published: June 2024

Au Maroc, pays profondément touché par la métropolisation, les zones agricoles situées à la périphérie des grandes villes subissent de rapides transformations économiques, sociales et paysagères. Ces changements sont particulièrement critiques pour le pays où l’agriculture et, plus généralement, la « ruralité » gardent une importance vitale. Au croisement du rural et de l’urbain, les périphéries sont prises entre une approche néolibérale, qui au nom de l’accumulation renforce l’assèchement des campagnes et l’étalement urbain, et une approche autoritaire, qui vise à préserver l’ordre social et politique impliquant de garder un œil sur la communauté rurale qui a traditionnellement soutenu le régime. Pour explorer cette contradiction, nous nous intéressons à la conurbation de Rabat-Salé-Témara. La première partie s’intéresse aux rapports de force entre les principaux acteurs de l’aménagement du territoire, afin d’analyser les contradictions affectant la fabrique des espaces périphériques. La deuxième partie expose les conséquences de ces rapports de force à travers les modèles de la ville nouvelle (Tamesna) et du grand projet (Bouregreg). La dernière partie analyse les enjeux de la reconfiguration des politiques étatiques face aux mutations produites par l’extension urbaine, en enquêtant dans deux communes rurales de deuxième couronne : Shoul et Sidi-Yahya-des-Zaërs (ZYS).
« Fini de jouer ». Entretien sur la sécurité dans les cercles anti-Jeux olympiques et paralympiques Paris 2024
Authors: Picaud Myrtille , Adam Matthieu
Published: June 2024

Organisés tous les quatre ans, les Jeux olympiques et paralympiques (JOP) transforment les villes où ils ont lieu et font évoluer les législations des pays qui les accueillent. Les JOP 2024, qui se déroulent à Paris à l’été 2024 ne font pas exception. Leurs effets sont multiples sur les plans économiques, politiques, sociaux et environnementaux. Parce que ces effets peuvent être analysés comme inégalitaires et autoritaires, les JOP sont la cible de critiques et de contestations. Dans cet entretien avec des membres de quatre collectifs mobilisés, à Marseille et à Saint-Denis, contre les JOP de Paris 2024, nous revenons sur la contestation des politiques de sécurité qui les accompagnent, qu’il s’agisse de vidéosurveillance, de contrôle policier ou de militarisation de l’espace. Nous discutons d’abord des formes — collecte d’informations, formation de collectifs, actions — que prend la contestation d’un évènement le plus souvent présenté comme populaire et rassembleur. Nous échangeons ensuite sur la construction des discours critiques des JOP, en France et ailleurs, et plus spécifiquement sur les enjeux de sécurité qui y sont liés. Nous concluons enfin sur l’écho qu’ont rencontré les militant.es, à la fois auprès de la population et des relais médiatiques.
Les coopératives de logements en Uruguay : habitat social et production sociale de l’habiter
Authors: Mariani Américo , Sánchez Marcelo Pérez
Published: June 2024

Cet article se penche sur l’expérience de logement coopératif uruguayen, en articulant le cadre d’une pensée matérialiste de l’habiter avec une critique du mode de production capitaliste. Il interroge cette forme de production sociale de l’habitat à la fois comme politique publique, comme mouvement de transformation sociale et comme procès de subjectivation individuelle. Après avoir présenté succinctement le modèle et précisé la réalité actuelle des coopératives, l’article aborde la question du changement social. Il interroge, à travers un entretien avec M. Pérez Sánchez, les questions de fonctionnement et de vie collective, les limites du modèle et pose la question des possibilités ouvertes par celui-ci en termes de centralité populaire.
Antimicrobial susceptibility pattern of bacteria isolated from patients with Otitis externa attending a tertiary health-care institution in Sokoto, Nigeria
Authors: Yabo Sufiyanu Umar , Iseh Kufre Robert , Mohammed Yahaya , Muhammad Bashar Goronyo
Published: June 2024

Background:

Otitis externa is the inflammation or infection of the skin of the external auditory canal, may be acute, subacute, or chronic and usually manifests by itching of the ear, otalgia, otorrhoea, aural fullness, and hearing loss. The causative agent is usually bacteria and occasionally fungi but may be associated with a variety of noninfective systemic or local dermatological conditions such as eczema, seborrhea, and contact dermatitis.

Aim:

This study aimed to determine the risk factors, bacterial profile, and antimicrobial susceptibility pattern of the isolates from patients with Otitis externa.

Methods:

A descriptive cross-sectional hospital-based study was conducted on 100 patients with Otitis externa. The ear discharge specimens were collected and analyzed by standard microbial techniques. The antibiotic susceptibility profiles were determined for 12 different antibiotics by the standard disk diffusion method. Data were analyzed with SPSS version 25 and the P < 0.05 was considered statistically significant.

Results:

The age of the 100 participants ranges from 4 to 57 years with a mean age of 18.78 ± 10.67 standard deviation, and the commonly affected age group was 11–20 years. Pathogens were isolated from 77 (62.1%) of the patients. The predominant isolate was Pseudomonas aeruginosa 32 (41.6%), followed by Staphylococcus aureus 13 (16.9%), others include Proteus mirabilis 7 (9.0%), Peptostreptococcus species 5 (6.5%), Escherichia coli 4 (5.2%), Streptococcus pneumonia 4 (5.2%), Klebsiella pneumonia 3 (3.9%), Streptococcus pyogenes 3 (3.9%), Enterobacter aerogenes 2 (2.6%), Fusobacterium species 2 (2.6%), and Bacteroides 2 (2.6%). Ofloxacin showed good susceptibility to isolated aerobes 65 (95.6%), followed by gentamicin 52 (76.5%) and ceftriaxone 50 (73.5%). All isolated anaerobes showed 100% susceptibility to metronidazole and clindamycin. Bacterial isolates identified in this study showed a trend of multiple drug susceptibility, majority (70%) being susceptible to three or more antimicrobials.

Conclusions:

Majority of the bacterial isolates were susceptible to more than one antimicrobial agent, hence efforts to isolate microorganisms and determine the susceptibility pattern should be strengthened to improve the treatment outcome of Otitis externa instead of the usual trend of empirical treatment.
Pediatric hearing screening: Exploring the need for a three-tier screening strategy
Authors: Das Soumyajit
Published: June 2024

Pediatric hearing impairment is a global health problem and has implications on the individual as well as the society. Undiagnosed hearing impairment has immense economic burden on the family, society, and nation. The challenge lies in diagnosing pediatric hearing impairment early so that effective treatment or rehabilitation can be initiated. Even though universal newborn hearing screening has been implemented in many countries, yet the coverage of the program has not been uniform throughout. Further, many cases of childhood deafness are known to manifest later in the school going age. As such, reliance on hearing screening in the newborn period alone will lead to many undiagnosed cases of hearing impairment. Therefore, a viewpoint is provided here for a three-tiered screening strategy so that maximum cases of hearing impairment can be diagnosed and effective treatment can be initiated, thereby reducing the global economic burden of pediatric hearing impairment.
Sternoclavicular joint tuberculosis
Authors: Jasti Navya , Arepalli Santhosh Kumar , Gopal G. Sivaram , Prasad V. Anjaneya , Ganti Eswar , Kadiyala Praneeth , Krishna Vadana Bala Murali
Published: June 2024

We studied five patients who presented with complaints of swelling of the sternoclavicular joint (SCJ), with pain and restriction of shoulder movements in some. There was no clinical or imaging evidence of pulmonary involvement in any of these patients. The diagnosis of SCJ tuberculosis (TB) was ascertained by histopathological evidence (n = 2), by Xpert MTB/RIF (n = 1) and based on clinical presentation and response to anti-TB treatment (n = 2). On follow-up, all patients had responded well to anti-TB treatment. TB should be considered in the differential diagnosis in patients presenting with subacute/chronic SCJ arthritis, with or without pulmonary involvement, especially in high TB burden countries.
Characteristics and outcomes of COVID-19 in pregnant women during the COVID-19 pandemic
Authors: Desai Suruchi , Tambe Rahul , Limaye Harshad , Raut Mihir , Bathija Manish , Verma Geeta , Shetty Tejal , Oswal Shreya
Published: June 2024

Background:

Pregnant women with severe acute respiratory syndrome coronavirus-2 disease 2019 [COVID-19] appear to be at greater risk of morbidity and mortality complications in pregnancy.

Objective:

This prospective analysis aimed to assess maternal and neonatal outcomes among hospitalized pregnant women with COVID-19.

Methods:

The present prospective study included COVID-19-positive pregnant women referred to our tertiary care centre. Data related to demographics, clinical characteristics, diagnosis, laboratory parameters, histopathological findings, procedure, treatment regimen and clinical outcomes were recorded. and analysed. We studied maternal and neonatal outcomes among hospitalised pregnant women with COVID-19.

Results:

During the period from April 2020 to April 2022, we studied 83 women clinically diagnosed with COVID-19. Placenta previa (n = 3), decrease in foetal movement (n = 2) and premature rupture of membranes (n = 1) were observed among pregnant women with COVID-19. A total of 31 women had pre-term delivery (<37 weeks gestation), 33 had normal term delivery (>37–<40 weeks gestation) and two had post-term delivery (>40 weeks gestation). Of these 83 patients, 17.6% had pneumonia, 14.7% had hypothyroidism, 8.8% had gestational diabetes mellitus and 5.9% had gestational hypertension. Elevated baseline C-reactive protein (21.6 mg/dL) and interleukin-6 (16.6 pg/mL) levels were observed. Mother-to-child COVID-19 transmission was observed in one neonate. The length of hospital stay had ranged from 2 to 77 days in COVID-19 positive mothers. Eighty two patients (98.8%) were managed conservatively and were successfully discharged.

Conclusions:

Our observations suggest that pregnant women with COVID-19 have a significant impact on maternal health and pregnancy outcomes.
Predictive factors for hypocalcaemia in post-thyroidectomy patients: A prospective cohort study
Authors: Neethu Francis , Arun Kizhakkepurakkal Vijayan , Pulluvelickal Mohanan Kesavan , Ajith Thekkuttuparambil Ananthanarayanan
Published: June 2024

Background:

Hypocalcaemia following thyroidectomy is a relatively common complication, which is sometimes difficult to correct.

Methods:

In this cohort study, we assessed the predictive factors for laboratory hypocalcaemia and symptomatic in patients who underwent thyroidectomy between January 2018–June 2019.

Results:

A total of 170 patients (153 women) were studied. Laboratory hypocalcaemia was found in 91.2% of patients, while 62.7% manifested symptomatic hypocalcaemia. Of the patients with symptomatic hypocalcaemia/(36%) had hypomagnesaemia as well. Univariate analysis revealed that type of disease (P = 0.0001), duration of surgery (P = 0.001), duration of disease (P = 0.005), type of surgery (P = 0.032) and hypomagnesaemia (P = 0.002) were significantly associated with hypocalcaemia. Age did not play a key role in the development of hypocalcaemia. Hypocalcaemia did not respond to supplementation without correcting the hypomagnesaemia.

Conclusions:

Type of disease, duration of disease, duration of surgery, type of surgery and hypomagnesaemia were risk factors. Age did not play a key role in the development of hypocalcaemia. Hypocalcaemia did not respond to supplementation without correcting the hypomagnesaemia. Adequate intervention can be started earlier to reduce the duration of hospital stay.
Monitoring the frequency of microalbuminuria in treatment-naïve hypertensives in a tertiary care teaching hospital in Andhra Pradesh, India
Authors: Konakanchi Sai Venkat , Chalamalasetty Manoj Kumar
Published: June 2024

Background:

Hypertension is a serious public health issue in the general population, with a considerable proportion of cases inadequately being treated.

Methods:

This hospital-based prospective study was carried out at our tertiary care teaching hospital between November 2019 and November 2021. One hundred patients who were recently diagnosed to have hypertension were studied.

Results:

The age of the subjects ranged from 31 to 78 years with a mean age of 49 years. Of these, 40% were in the 40–49 years’ age group; there were 68 males. The body mass index (BMI, Kg/m2) distribution of the study subjects showed 22% with normal weight, 62% in overweight and 16% in obese category. Microalbuminuria was evident in 28% of newly diagnosed hypertensives. The sex-wise distribution of microalbuminuria revealed that 17 of 68 males (25%) and 11 of 32 females (34.4%) had microalbuminuria.

Conclusions:

The chronicity of hypertension, age and BMI were the main factors determining microalbuminuria.
Predictors of subclinical atherosclerosis in patients with rheumatoid arthritis
Authors: Narayan Ankitha Teja , Savith Akshatha , Madhuri M. S. , Kumar R. Mahesh , Halambar C. Jithendra
Published: June 2024

Background:

Rheumatoid arthritis (RA) is a chronic inflammatory disorder involving the joints along with various other extra-articular manifestations. Mortality due to coronary artery disease is higher in patients with RA when compared to the general population. Hence, this study is undertaken to assess the predictors of sub-clinical atherosclerosis in patients with RA, so that early prompt management can prevent cardiovascular complications.

Methods:

A case–control study with 42 patients of RA and 42 healthy age- and sex-matched controls was undertaken. Relevant investigations were done. Disease Activity Score (DAS)-28 was calculated. Carotid artery doppler was performed on both sides to examine the common carotid artery.

Results:

The mean carotid intima–media thickness (CIMT) (mm) was significantly higher in RA patients compared to controls on the right side (0.57 ± 0.11 Vs 0.40 ± 0.03; P < 0.001) as well as left side (0.56 ± 0.11 Vs 0.39 ± 0.06; P < 0.001). Only age (P = 0.006) and DAS-28 (P = 0.002) showed a positive correlation with CIMT.

Conclusions:

CIMT can be used as a marker for the detection of subclinical atherosclerosis and the risk of atherosclerosis increases with the increasing age and increasing disease severity.
Biological Width around One- and Two-piece Implants: A Systematic Review
Authors: Srivastava Sumedha , Kalburgi Veena , Banerjee Nilojjawala , Tripathi Bimmi , Jain Milan , Singh Shivam
Published: June 2024

The concept of biological width (BW) around dental implants is crucial for the long-term success of implant placement. This systematic review aimed to investigate the differences in BW around one- and two-piece dental implants and to assess the impact of implant design on peri-implant soft tissues. To compare biological width around one-piece and two-piece implant in a population undergone implant treatment. A comprehensive search of MEDLINE (via PubMed), EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), Scopus, Web of Science, CINAHL, PsycINFO, and Google Scholar was conducted to identify studies that compared the BW around one- and two-piece dental implants. Eligibility criteria included published peer-reviewed studies that provided quantitative measurements of BW and related soft-tissue dimensions. Data extraction and synthesis were performed, and the findings were compared for consistency and relevance to the research question. The review included four studies that met the inclusion criteria. Two studies suggested that two-piece implants might lead to an adaptive change in BW and marginal bone levels over time. One study indicated that one-piece implants could maintain a BW and gingival margin position similar to that of natural teeth, while another found no significant long-term differences in soft-tissue volumetric stability between the one- and two-piece systems. The evidence pointed toward the microgap and implant design as influential factors in determining peri-implant soft-tissue dimensions. We found that implant design, particularly the presence of a microgap, plays a significant role in the establishment and maintenance of BW around dental implants. Two-piece implants may induce a greater adaptation in BW, whereas one-piece implants may better mimic the natural soft-tissue architecture. Long-term volumetric stability of the soft tissues appeared to be comparable between the two systems. These findings can inform clinical decision-making regarding the choice of implant systems for optimal soft-tissue health and integration.
Clinical Effectiveness of Immediate Implant Placement along with Demineralized Freeze-dried Bone Allograft – A Systematic Review and Meta-analysis
Authors: Kalburgi Veena , Jain Megha , Bhole Shravani , Bagewadi Shivanand , Gupta Sagar , Katiyar Rachna
Published: June 2024

The field of dental implantology constantly pursues materials and methods to enhance the success of implant procedures. Among these, demineralized freeze-dried bone allograft (DFDBA) has been extensively utilized. However, its outcomes vary depending on the implant type and clinical protocol used. In this regard, this study aimed to collectively assess the clinical and radiographic outcomes of DFDBA in dental implant procedures across different studies. A comprehensive search was conducted across eight different online databases in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses protocol. Appropriate Medical Subject Headings words and Boolean operators were used. Two reviewers extracted the data based on preset criteria. The risk of bias-2 (ROB-2) tool was utilized for the assessment of ROB. Quantitative analysis was performed using RevMan 5.4 software employing a random effect model to accommodate heterogeneity. Clinical findings across the four studies selected for the review revealed a consistent pattern of stable or improved peri-implant health and reduced postoperative pain. Associated assessments indicated active bone remodeling, successful osseointegration, and implant stability over time. However, the outcomes were influenced by various factors, including the clinical protocol used, the type of implant, and the specific assessment measures employed. Statistical results showed a notable increase in bone height in the mesial side during the follow-up period with a mean difference of 0.60 (95% confidence interval: 0.27–0.94) significant at P = 0.004. All the studies were of good quality as assessed by ROB-2. The collective evidence supports the effective use of DFDBA in maintaining peri-implant health, managing postoperative discomfort, and promoting bone remodeling and implant stability. Still, the variability of outcomes underscores the importance of individualized patient assessment and treatment planning in dental implant procedures.
Effect of Timing of Pars Plana Vitrectomy on Visual Outcome in Cases of Nucleus Drop during Phacoemulsification
Authors: Sharma Deepa , Ish Somya , Jeria Satish , Dalla Ritu , Pathak Ashok
Published: June 2024

PURPOSE:

The purpose of the study was to study the relationship between the timing of pars plana vitrectomy (PPV) with corrected distance visual acuity (CDVA) in cases of nucleus drop during phacoemulsification.

METHODS:

This retrospective analysis included 83 patients, who underwent PPV for nucleus or nuclear fragment drop from July 2017 to November 2019. Timing of PPV (≤2 weeks and >2 weeks) after the primary cataract surgery was noted. The primary endpoint was CDVA at 1 month, which was compared with the time of PPV. Visual outcome was assessed as good if CDVA was better than or equal to 20/40 and poor if CDVA was worse than 20/40. Mode of management along with type of secondary intraocular lens (IOL) implanted was also evaluated.

RESULTS:

Out of the 83 cases (55 males and 28 females) in which vitrectomy for nucleus drop was performed, 36 cases were operated within 2 weeks and 47 were operated between 2 weeks and 1 month. In cases which were operated within 2 weeks, CDVA of 20/20–20/40 was achieved in 33 cases. For those who were operated on after 2 weeks, CDVA of 20/20–20/40 was achieved in 43 cases. The difference in visual outcome in both the groups was statistically nonsignificant (Fisher’s exact t-test, P = 0.97). In 64 (77%) cases, adequate sulcus was present, in which foldable 3-piece IOL was placed in 29 (35%) cases.

CONCLUSION:

Timing of intervention has no bearing on the final visual outcome after vitrectomy in cases of nucleus drop during phacoemulsification. The continuity of the capsulorrhexis and the availability of capsular support determines the type of placement of the lens. A foldable lens can be placed in the sulcus if continuous capsulorrhexis is present.
Recurrence of Idiopathic Orbital Inflammation: An 11-year Retrospective Study
Authors: Anggraini Neni , Siregar Nurjati C. , Sitorus Rita S.
Published: June 2024

PURPOSE:

The high recurrence rate of idiopathic orbital inflammation (IOI) has been reported. This study aims to determine existing predictive factors for the recurrence of IOI.

METHODS:

This was an 11-year retrospective study with at least a 12-month follow-up. Fifty patients with biopsy-proven IOI admitted between 2006 and 2017 at our tertiary hospital were observed. We compared the clinical characteristics, histopathological profile, and biomarker expressions (mast cell, immunoglobulin G4, tumor necrosis factor-alpha, and transforming growth factor-beta) of 16 patients with recurrence (Group I) and 34 patients with no recurrence (Group II). Statistical comparison and multivariate analysis were performed to establish the predictive factors.

RESULTS:

We discovered five recurrence predictive factors: presentation of proptosis (odds ratio [OR] 4.96, 95% confidence interval [CI] 1.36–18.03), visual impairment (OR 15, 95% CI 1.58–142.72), extraocular muscle (EOM) restriction (OR 3.86, 95% CI 1.07–13.94), nonanterior involvement (OR 7.94, 95% CI 1.88–33.5), and corticosteroid (CS) alone treatment (OR 7.20, 95% CI 1.87–27.8). On multivariate analysis, nonanterior involvement and CS alone treatment were validated as predictive factors (area under the curve = 0.807 [95% CI 0.69–0.92]). Histopathological profile and biomarker expressions were not associated with recurrence. However, there was a 22-fold higher recurrence risk for granulomatous-type patients given CS alone treatment.

CONCLUSION:

Unlike the five clinical characteristics mentioned, both histopathology and biomarker variables were not associated with recurrence. CS alone treatment for patients with nonanterior involvement or granulomatous type is proven to increase the risk of recurrence. Therefore, we suggest not giving CS without any combination treatment with other modalities for this group of patients.
Spontaneous Globe Rupture following Prolonged Uncontrolled Elevated Intraocular Pressure
Authors: Aina Akinsola S. , Adeleke Olumide T. , Aina Ifeoluwasemilojo
Published: June 2024

We report two glaucoma patients who experienced unusual instances of spontaneous globe rupture. The patients arrived at the Bowen University Teaching Hospital’s emergency ophthalmology unit with a history of bleeding from one eye without any history of ocular trauma. They were known glaucoma patients with poor control of their intraocular pressures (IOP). They eventually underwent evisceration shortly after presentation. Spontaneous eyeball rupture in glaucomatous eyes is extremely unusual and has a very poor prognosis for vision. Proper management and appropriate follow-up of glaucoma patients are very important to avert this dreaded complication of uncontrolled IOP.
Radiopathological Correlation in Orbital Lesions
Authors: Mukherjee Bipasha , Backiavathy Varsha , Umadevi C. , Noronha Olma V.
Published: June 2024

PURPOSE:

The objective is to analyze the radiological diagnosis of orbital lesions and their correlation with the final histopathological findings. We compared the initial reports by extramural radiologists and an in-house radiologist specialized in orbital imaging to evaluate the diagnostic accuracy in the interpretation of orbital imaging.

METHODS:

This was a retrospective chart review of forty patients referred to a Tertiary Eye Care Center in South India over a period of 7 years. These patients already had their imaging done elsewhere. The imaging was re-evaluated by an in-house radiologist. The radiological findings were correlated with the histopathological diagnosis. The diagnostic accuracy between the two radiologists was compared. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value in differentiating malignant from benign lesions were calculated in both groups. The sensitivity and PPV of the radiological diagnosis for neoplastic and inflammatory lesions in both groups were analyzed.

RESULTS:

The accuracy in differentiating malignant from benign and inflammatory lesions by our in-house radiologist and extramural radiologists was 95% (κ = 0.9 [0.764, 0.997]) and 50% (κ = 0.036 [−0.160, 0.232]), respectively. The sensitivity and PPV of the radiological diagnosis by our in-house radiologist were 93.31% and 100% for benign lesions and 95.24% and 95.24% for malignant lesions. On the contrary, reports from the extramural radiologists showed a sensitivity and PPV of 76.92% and 66.67% for benign lesions and 14.28% and 60% for malignant lesions.

CONCLUSION:

A high radiological diagnostic accuracy is possible when analyzed by radiologists experienced in orbital imaging.
Development and Analysis of a Multibody Dynamics Suspension Air
Spring Model as a Function of Sprung Mass, Un-Sprung Mass, and Design
Height
Authors: Adams Bailey
Published: June 2024

Air spring systems are challenging to mathematically model due to the complexity
of their nonlinear dynamic characteristics. Numerous air spring mechanical and
thermodynamic models have been proposed, but this study focused on the
development and analysis of a new thermodynamic air spring model under a
polytropic thermodynamic process that could accurately represent the force
output in a multibody dynamics (MBD) virtual suspension subsystem. This model
considered function inputs of sprung mass, un-sprung mass, and design height to
efficiently generate updated air spring properties for new vehicle
configurations, specifically for a self-propelled sprayer application. After
this model was validated against physical ground-truth sensor data, it was
utilized in a sensitivity study to experimentally test an alternative air spring
component and to understand the resulting performance effect on an operator
comfort key performance indicator.
Hydrogen Surface Vehicle to Station Communications Hardware and Software
Authors:   Fuel Cell Standards Committee
Published: June 2024

This standard specifies the communications hardware and software requirements for fueling hydrogen surface vehicles (HSV), such as fuel cell vehicles, but may also be used where appropriate with heavy-duty vehicles (e.g., buses) and industrial trucks (e.g., forklifts) with compressed hydrogen storage. It contains a description of the communications hardware and communications protocol that may be used to refuel the HSV. The intent of this standard is to enable harmonized development and implementation of the hydrogen fueling interfaces.

This standard is intended to be used in conjunction with the hydrogen fueling protocols in SAE J2601 and nozzles and receptacles conforming with SAE J2600.
Interconnection Requirements for Onboard, Grid Support Inverter Systems
Authors:   Hybrid - EV Committee
Published: June 2024

SAE J3072 establishes requirements for a grid support inverter system function that is integrated into a plug-in electric vehicle (PEV), which connects in parallel with an electric power system (EPS) by way of conductively coupled, electric vehicle supply equipment (EVSE). This standard also defines the communication between the PEV and the EVSE required for the PEV onboard inverter function to be configured and authorized by the EVSE for discharging at a site. The requirements herein are intended to be used in conjunction with IEEE 1547-2018 and IEEE 1547.1-2020 or later versions.
PEMBENTUKAN STRATEGI MELALUI AUDIO KOMUNIKASI DALAM APLIKASI GAME FPS(VALORANT)
Authors: Muzakki Ahmad , Syariati Ahmad Hasyeimi , Darussalam Kholdi , Nopriyani Fathiyah
Published: June 2024

This research discusses the influence of online games, especially the FPS game Valorant, in daily life and PC application development. Valorant is a popular FPS game and has active users in Indonesia. This game offers uniqueness with agent characters who have special skills. Although the Valorant game can make players addicted, this game also provides opportunities to make money and achievements in the world of e-sports. Strategy is also an important factor in the Valorant game, including selecting equipment purchasing items. Communication is also an important aspect in this game, with an audio communication feature that makes it easier for players to communicate and plan strategies. This research uses the UX Research method to understand user experience and analyze the data obtained.
ANALISIS DAN PERANCANGAN SISTEM INFORMASI ADMINISTRASI KEPENDUDUKAN PADA KANTOR DESA BANDAR KLIPPA MENGGUNAKAN FRAMEWORK LARAVEL
Authors: Pratiwi Diah , Hasdiana Hasdiana
Published: June 2024

Pelayanan administrasi kependudukan pada Kantor Desa Bandar Klippa saat ini masih menggunkan cara manual yaitu dalam proses pembuatan surat masih menggunakan Microsoft Word, pengolahan data penduduk masih menggunakan Microsoft Excel, pengolahan arsip masih menggunakan buku agenda dan pembuatan laporan masih secara tertulis. Tujuan penelitian ini adalah untuk menganalisis dan merancang sistem informasi administrasi kependudukan pada Kantor Desa Bandar Klippa menggunakan Framework Laravel. Penelitian ini guna untuk memudahkan pelayanan administrasi kependudukan, dalam pembuatan surat, pengolahan data penduduk dan juga pengolahan arsip dan laporan pada Kantor Desa Bandar Klippa Kecamatan Percut Sei Tuan Kabupaten Deli Serdang. Adapun teknik pengumpulan data dalam skripsi ini menggunakan teknik observasi, wawancara dan kepustakaan. Aplikasi ini menggunakan metode Waterfall yang merupakan salah satu dari beberapa metode SDLC digunakan sebagai tools untuk menganalisis dan merancang sistem informasi administrasi kependudukan. Kata Kunci :Sistem Informasi, Kependudukan, Framework Laravel, Waterfall, Website
PENERAPAN STRAIGHT LINE METHOD DALAM MENENTUKAN PENYUSUTAN ASET PADA SEKOLAH SMP NEGERI 35 MEDAN BERBASIS WEB
Authors: Lubis Muhammad Shirath , Sembiring Boni Oktaviana , Irwan Dedy
Published: June 2024

SMP 35 Medan, yang berlokasi di Jl. Williem Iskandar Psr 5 Medan, menghadapi tantangan terkait ketidakakuratan dalam perhitungan penyusutan aset. Metode yang digunakan untuk menentukan nilai penyusutan aset seringkali tidak sesuai dengan standar akuntansi yang berlaku, sehingga laporan keuangan tidak mencerminkan kondisi keuangan sekolah yang sebenarnya. Hal ini menghambat proses pengambilan keputusan yang tepat oleh staf sekolah. Untuk mengatasi masalah ini, penulis mengusulkan penerapan Metode Garis Lurus untuk menghitung penyusutan aset di SMP 35 Medan. Metode ini membagi penyusutan aset secara merata selama masa pakai ekonomisnya, sehingga setiap tahun terjadi penurunan nilai aset yang adil akibat penggunaan dan usia aset. Temuan penelitian menunjukkan bahwa penerapan metode garis lurus untuk penyusutan aset pada sistem berbasis web SMP Negeri 35 Medan adalah langkah penting menuju manajemen aset sekolah yang lebih efisien. Kata kunci: SMP 35 Medan, Metode Garis Lurus, Aset TetapAbstract
IMPLEMENTASI MEDIA BELAJAR BERBASIS POWTOON PADA SEKOLAH SMP NEGERI 1 PERCUT SEI TUAN
Authors: Sirait Faisal Amrullah , Usman Ari , Sarudin Sarudin
Published: June 2024

Implementasi media pembelajaran dapat dirangsang sedemikian rupa sehingga peserta didik dapat melakukan kegiatan belajar dengan lebih leluasa dimanapun dan kapanpun tanpa tergantung seorang guru. Multimedia interaktif merupakan suatu multimedia yang dilengkapi dengan alat pengontrol yang dapat dioperasikan oleh pengguna, sehingga pengguna dapat memilih apa yang dikehendaki untuk proses selanjutnya, seperti multimedia interaktif adalah pembelajaran interaktif dan aplikasi game. Powtoon adalah aplikasi atau software web berbasis IT yang dapat digunakan sebagai media pembelajaran yang didalamnya terdapat fitur-fitur menarik seperti fitur untuk membuat presentasi atau video animasi yang dapat digunakan dengan mudah, menarik dan menyenangkan bagi banyak orang dan siswa, seperti yang diterapkan pada siswa sekolah SMP Negeri 1 Percut Sei Tuan. Meski demikian terdapat beberapa problematika dari penggunaan aplikasi Powtoon dimana sebagai aplikasi video animasi berbasis online tentulah membutuhkan keberadaan sarana teknologi seperti internet. Kata kunci: Implementasi Media, Software Powtoon, Sekolah, Multimedia Interaktif