bluuebunny/crossref_metadata_2025 huggingface dataset:
Design of a Database-Driven Kansei Feedback Control System Using a Hydraulic Excavators Simulator
Authors: Kinoshita Takuya , Ikeda Hiroaki , Yamamoto Toru , Machizawa Maro G. , Tanaka Kiyokazu , Yamazaki Yoichiro ,   Graduate School of Advanced Science and Engineering, Hiroshima University 1-4-1 Kagamiyama, Higashi-hiroshima, Hiroshima 739-8527, Japan,   Graduate School of Engineering, Hiroshima University 1-4-1 Kagamiyama, Higashi-hiroshima, Hiroshima 739-8527, Japan,   Center for Brain, Mind and KANSEI Sciences Research, Hiroshima University 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8553, Japan,   KOBELCO Construction Machinery Co., Ltd. Osaki Bright Core Bldg., 5-15 Kitashinagawa 5-chome, Shinagawa-ku, Tokyo 141-8626, Japan
Published: June 2020

In Japan, the level of happiness is considered low despite the gross domestic product (GDP) being high, and a wide gap separates “products wealth” related to GDP and “mental wealth such as Kansei” related to the level of happiness. To fill this gap, products should be controlled to enhance Kansei according to human feelings. However, it is difficult to obtain the Kansei model because of time-variant and nonlinear system. In this paper, the design of a data-oriented cascade control system based on Kansei is newly proposed. In particular, a database-driven controller is designed for a human based on Kansei. The effectiveness of the proposed scheme is verified by using the electroencephalograph (EEG).
Development of a Rehabilitation and Training Device Considering the Ankle Degree of Freedom
Authors: Akagi Asaki , Tsuichihara Satoki , Kosugi Shinichi , Takemura Hiroshi ,   Tokyo University of Science 2641 Yamazaki, Noda, Chiba 278-8510, Japan,   Nara Prefecture Seiwa Medical Center 1-14-16 Mimuro, Ikoma Sango, Nara 636-0802, Japan
Published: June 2020

While the number of people who need rehabilitation has been increasing because of the aging population, there are only a limited number of physical therapists engaged in rehabilitation, making it difficult to perform rehabilitation at a sufficient level. In this situation, various devices have been developed to replace physical therapists. However, no rehabilitation devices that can respond to the complicated degrees of freedom of an ankle joint complex (AJC) are commercially available. In the present study, we developed an AJC rehabilitation device using a Stewart platform parallel link mechanism. Using the device, we aim to measure and control the AJC with six degrees of freedom so that complicated composite motions of the AJC can be realized. To evaluate the device’s usefulness, we investigated how the composite motion generated by moving the AJC along the trajectory the device reproduced could influence a crural muscle. Muscular activities of the anterior tibial, soleus, and gastrocnemius muscles, generated by a composite motion of plantar flexion and inversion, had a similar feature to those generated by plantar flexion. However, the muscular activity of the peroneus longus muscle generated in the composite motion was significantly different from that generated only in plantar flexion. In the composite motion of plantar flexion and inversion, based on the knowledge that activity to develop only back muscles while suppressing muscular activities of the anterior tibial and peroneus longus muscles is possible. Based on the knowledge, the device was used to perform isokinetic contraction for evaluating the device’s usefulness for muscular training. We found a difference between the combination of active muscles during the composite motion and that during plantar flexion. A load can be applied to different muscles depending on the composite motion, which indicates that the device can be suitable for rehabilitation or training with high degrees of freedom.
Fogyasztóvédelem a villamosenergia szolgáltatás területén
Authors: Barta Judit
Published: June 2020

This research studies the law measures of the European Union aiming Energy Union regarding consumer protection in the view of the process of the legislation of the consumer protection, the development of the consumer rights up until the latest Directive 2019/944. Provisions of consumer protection of the Directive are reviewed. The second part of this research looks at the consumer protection on the fields of the electricity service in Hungary, considering how much it complies with the EU regulation.
Villamosenergiatermelés és környezeti hatásai
Authors: Bodnár István , Matusz-Kalász Dávid , Faragó Dávid , Palotás Árpád Bence , Siménfalvi Zoltán Károly
Published: June 2020

Nowadays, increasing energy demand poses increasing challenges to professionals. While aligning with international guidelines and changing societal attitudes urge to prefer renewables and increase efficiency of electric power consumption. Replacing the current aging power plant system holds several issues and tasks that may not have been explored so far. To get an accurate, comprehensive view of these, it is essential to apply full life cycle analysis to ensure sustainable energy production.
The preemption right on agricultural land in Slovenia: past developments and future challenges
Authors: Avsec Franci
Published: June 2020

The paper outlines statutory preemption rights relating to agricultural land in Slovenia, in particular the priority right to purchase agricultural land which is regulated by the Agricultural Land Act. This preemption right has a general scope and a long tradition (of nearly 60 years). In the previous legal system, based on the social ownership as basic ownership form, the statutory preemption right on agricultural land was first introduced for agricultural organisations and later also for private farmers (who were ranked after agricultural organisations). At first, the preemption right related only to privately owned agricultural land and had a limited impact for farmers due to agricultural land maximum. After the agricultural land maximum was abolished in the beginning of the 1990s and the statutory preemption right was extended to all agricultural land, the development has been characterised by endeavours to make the statutory preemption right more efficient in practice and consistent with the principle that restrictions the legislator imposes on the constitutionally guaranteed private property must be in public interest and proportional. A Draft Act launched for public consultation in spring 2019 foresaw several substantial changes of the statutory preemption right linking this right more closely to farm structure improvement and overall agricultural policy, but has not been further elaborated after the consultation was  closed  in May 2019.
KARAKTERISASI BAKTERI DARI PERAKARAN Nepenthes mirabilis UNTUK PENGENDALIAN HAYATI Fusarium oxysporum
Authors: Mardhiana NFN , Adiwena Muh. , Pradana Ankardiansyah Pandu
Published: June 2020

Phytopathogenic fungi Fusarium oxysporum causes significant yield losses in various spices plants. The fungus can be controlled with numerous types of antagonistic bacteria. This study aimed to determine the physiological characteristic and antagonistic properties of the bacterial from the roots of Nepenthes mirabilis, as a biological control to F. oxysforum. The study was conducted at the Plant Protection Laboratory, Faculty of Agriculture, the University of Borneo, Tarakan, from October to November 2017. Nutrient Agar medium was used to isolate antagonistic bacteria from the roots of N. mirabilis. Biosafety test against plants and mammals were conducted using hypersensitive and hemolysis analysis. The bacterial isolates passed from those tests were characterized further for their phenotype and physiological properties as well as their ability to inhibit the growth of F. oxysporum in a dual culture test  in  vitro.  The  results  showed  that  there  were  10  out  of26 bacterial isolates originated from N. mirabilis roots that were safe for plants and mammals. Physiological tests showed  that four  isolates  could produce the proteolytic enzyme, five isolates produced the chitinolytic enzyme, six isolates were able to dissolve phosphate, and four isolates could produce HCN. Furthermore, three isolates (Mrb2, Mrb6, and Mrb16) showed inhibitory activity against Fusarium spp. There were differences in the phenotype character and physiological activity between the Mrb2, Mrb6, and Mrb16 isolates, but all three have the potential to inhibit F. oxysporum.
Aplikasi Berbagai Konsentrasi Giberelin (GA3) Terhadap Pertumbuhan Tanaman Kailan (Brassica oleracea L.) pada Sistem Budidaya Hidroponik
Authors: Riko NFN , Aini Sitti Nurul , Asriani Euis
Published: June 2020

[Application of Various Concentrations of Gibberellin (GA3) on Kailan
(Brassica oleracea L.) Growth with Hydroponic Cultivation System]

Giberelin adalah zat pengatur tumbuh yang banyak digunakan untuk merangsang pertumbuhan dan perkembangan pada tanaman, termasuk pada tanaman kailan yang banyak dikonsumsi. Penelitian ini bertujuan mengetahui pengaruh zat pengatur tumbuh giberelin dan konsentrasinya yang optimal terhadap pertumbuhan tanaman kailan. Penelitian ini dilaksanakan pada bulan Maret - Mei 2019 di Kebun Percobaan Fakultas Pertanian, Perikanan dan Biologi, Universitas Bangka Belitung. Rancangan percobaan yang digunakan adalah Rancangan Acak Lengkap (RAL) dengan perlakuan giberelin konsentrasi (0 ppm, 20 ppm, 40 ppm, 60 ppm, 80 ppm, dan 100 ppm) diulang empat kali. Pemberian giberelin dilakukan dengan cara perendaman benih sebelum tanam dan dilakukan penyemprotan pada tanaman kailan yang dilakukan dua kali dalam seminggu, dimulai 7 hari setelah tanam. Hasil penelitian menunjukkan bahwa penambahan giberelin dengan konsentrasi 100 ppm memberikan hasil yang tinggi pada tinggi tanaman, diameter batang, luas daun, bobot segar tajuk, dan bobot kering tajuk, dengan persentase kenaikan produksi sebesar 50% dibandingkan kontrol.

Keywords

Kailan; Giberelin; Hidroponik

Abstract

Gibberellin are plant growth regulators that are widely used to stimulate plants growth and development, including widely consumed Brassica oleracea L. plants. The aims of study to determine the effect of gibberellin and its concentration on growth. The research was conducted in March until May 2019 at experimental garden of the Faculty of Agriculture, Fisheries and Biology, Bangka Belitung University. The experimental design used was a Completely Randomized Design (CRD) with the treatment were concentrations of gibberellin (0 ppm, 20 ppm, 40 ppm, 60 ppm, 80 ppm, and 100 ppm) with four replication. Gibberelin applied by soaking the seeds before planting and spraying the plants twice a week starting 7 days after planting. The results showed that the application of 100 ppm gibberellins gives the best results on plant height, stem diameter, leaf area, canopy fresh weight, and canopy dry weight, with a percentage increase in production by 50% compared to control.
EFEKTIVITAS BEBERAPA DEPOSIT FOSFAT ALAM INDONESIA SEBAGAI PUPUK SUMBER FOSFOR TERHADAP PERTUMBUHAN BIBIT KELAPA SAWIT PADA TANAH ULTISOLS
Authors: KASNO A. , SUDIRMAN SUDIRMAN , SUTRIADI M.T.
Published: June 2020

ABSTRAK

Penelitian bertujuan untuk mempelajari pengaruh fosfat alam asalIndonesia terhadap kadar P dalam tanah dan pertumbuhan kelapa sawit.Penelitian dilaksanakan di rumah kaca Balai Penelitian Tanah di Laladon,Bogor dari bulan Juni sampai Desember 2009, dengan menggunakanrancangan percobaan acak kelompok dengan 8 perlakuan dan diulang 5kali. Perlakuan yang dicoba adalah 5 P-alam asal Indonesia, ditambahSuperphos, P-alam Tunisia, dan kontrol. Tanah yang digunakan adalahTypic Kanhapludults dan Typic Plinthudults yang diambil dari Lampung,dengan tanaman indikator adalah kelapa sawit. Hasil penelitianmenunjukkan bahwa pemupukan P nyata meningkatkan diameter batang,tinggi tanaman, berat akar dan berat kering tanaman. Pemupukan P denganSuperphos memberikan peningkatan yang lebih tinggi daripada pemu-pukan dengan fosfat alam. Efektivitas pupuk P-alam pada TypicPlintudults lebih rendah dibandingkan pada Typic Kanhapludults. PupukP-alam dari Indonesia sama efektifnya dengan P-alam Tunisia untukpemupukan tanaman kelapa sawit. Pemupukan P dengan Superphos padatanaman kelapa sawit nyata meningkatkan kadar P tanah lebih tinggidaripada kadar P tanah yang dipupuk P-alam. Pemberian pupuk P belumberpengaruh terhadap kadar P dalam akar dan tanaman kelapa sawit dalampembibitan.

Kata kunci: Elaeis guinensis, kelapa sawit, tanah masam, fosfat alam

ABSTRACT

Effectiviness of several rock phosphate deposites fromIndonesia as P fertilizer sources on the growth of oilpalmseedling on ultisols

The aim of this research was to study the effect of rock phosphatefrom Indonesia on P content on the soil and growth of oil palm. Thisresearch was conducted at the glass house of Indonesian Soil ResearchInstitute, Laladon Bogor from June to December 2009, using randomizedcomplete block design (RCBD) with 8 treatments and 5 replicates. Thetreatments were 5 types of Indonesia rock phosphate, Superphos, Tunisiarock phosphate, and control. The soils used were Typic Kanhapudults andTypic Plinthudults, and oil palm nursery as plant indicator. The resultshowed that P fertlizer was significant to increase trunk diameter, plantheight, root weight, and plant dry weight. Superphos fertilizer increasedtrunk diameter, plant height, root weight, and plant dry weigth better thanrock phosphate. Effectivity of rock phosphate at Typic Plinthudults waslower than at Typic Kanhapludults. Indonesian rock phosphate waseffective for fertilizing oil palm, as well as Tunisia rock phosphate. Pfertilization using Superphos significantly increased P soil content and wasbetter than rock phosphate. Application of rock phosphate did notinfluence P contents in root and plant of oil palm in nursery.

Key words: Elaeis guinensis, oil palm, acid soils, rock phosphate
PENGARUH PEMBERIAN GA 3 PADA BERBAGAI KONSENTRASI DAN LAMA IMBIBISI TERHADAP PENINGKATAN VIABILITAS BENIH PURWOCENG (Pimpinella pruatjan Molk.)
Authors: RUSMIN DEVI , SUWARNO FAIZA C. , DARWATI IRENG
Published: June 2020

ABSTRAK

Purwoceng (Pimpinella pruatjan Molk.) merupakan tanaman herbatahunan dari famili Apiaceae, yang hidup secara endemik pada habitatdengan ketinggian 1.800 - 3.000 m dari muka laut, dan pada saat initergolong tanaman langka. Salah satu permasalahan dalam pengembangantanaman ini adalah viabilitas benih saat masak fisiologis rendah (<25%).Berdasarkan hal tersebut telah dilakukan percobaan yang bertujuan untukmengetahui tingkat konsentrasi GA 3 dan lama imbibisi yang tepat untukmeningkatkan viabilitas potensial dan vigor benih purwoceng. Percobaandilaksanakan di Laboratorium Ekofisiologi, Balai Penelitian TanamanObat dan Aromatik, Bogor mulai bulan November sampai denganDesember 2009. Rancangan percobaan yang digunakan adalah rancanganacak lengkap (RAL), dengan 2 faktor dan tiga ulangan. Faktor pertamaadalah enam taraf pemberian GA 3 , yaitu: 0, 100, 200, 300, 400, dan 500ppm. Faktor kedua yang diuji dua taraf lama imbibisi benih yaitu: 24 dan48 jam. Hasil penelitian menunjukkan bahwa, pemberian GA 3 400 ppmdengan lama imbibisi 48 jam dapat meningkatkan daya berkecambah,potensi tumbuh maksimum, indeks vigor, dan kecepatan perkecambahanbenih purwoceng menjadi 1,5 - 2 kali dibandingkan tanpa pemberian GA 3.

Kata kunci: Pimpinella pruatjan, benih, GA 3 , imbibisi, konsentrasi

ABSTRACT

Effect of GA 3 Concentration and Imbibition Period onSeed Viability of Pruatjan

Pimpinella pruatjan Molk. is an annual herbaceous plant andbelongs to the family of the Apiaceae. It lives in endemic with an altitudeof 1,800-3,000 m above sea level and has been currently classified as rareplant. One of the problems in the development of this crop is low in seedviability (<25%) when it is physiologically mature. Based on the problem,an experiment was conducted aiming to find out the level of GA 3concentration and imbibition period to increase seed viability and vigourof P. pruatjan. The experiment was conducted at Gunung PutriExperimental Station and Plant Physiology Laboratory of the IndonesianMedicinal and Aromatic Crops Research Institute (IMACRI), fromNovember to December 2009. The experiment was arranged usingcompletely randomized design (CRD), with 2 factors and three replicates.The first factor was level of GA 3 concentration : 0, 100, 200, 300, 400, and500 ppm. The second factor was seed imbibition period : 24 and 48 hours.Results of the experiment showed that: GA 3 400 ppm with imbibitionperiod of 48 hours improved seed germination, maximum growthpotential, vigor index, and rate of germination of purwoceng seed to 1.5- 2 times compared to without GA 3 treatment.

Key words: Pimpinella pruatjan, seed , GA 3 , imbibition, concentration
DAYA SIMPAN BENIH RIMPANG JAHE PUTIH BESAR DI DATARAN TINGGI DENGAN PERLAKUAN PESTISIDA NABATI DAN ANALISIS EKONOMINYA
Authors: SUKARMAN SUKARMAN , ERMIATI ERMIATI
Published: June 2020

ABSTRAK

 
PENGARUH SISTEM PENANAMAN TERHADAP PRODUKSI BENIH G0, G1, DAN G2 BEBERAPA VARIETAS TEBU UNGGUL HASIL KULTUR JARINGAN
Authors: SUKMADJAJA DEDEN , SYAKIR MUHAMMAD
Published: June 2020

ABSTRAK
Penyediaan benih tebu berdaya hasil tinggi memegang peranan
penting  dalam  mendukung  pencapaian  program  swasembada  gula.
Produksi benih tebu melalui teknologi kultur jaringan merupakan salah
satu alternatif untuk menyediakan benih bermutu secara masal dengan
waktu yang cepat. Salah satu bagian penting dalam program produksi
benih tebu adalah penanganan benih hasil kultur in vitro menjadi benih
produksi di lapangan. Penelitian ini bertujuan untuk mendapatkan metode
penanaman benih primer (G0), sekunder (G1), dan komersial (G2) dari
beberapa varietas tebu hasil kultur in vitro. Penelitian dilakukan di tiga
lokasi, yaitu Kebun Percobaan Cibinong-Bogor, Ngemplak-Pati, dan
Klari-Karawang. Percobaan terdiri atas tiga kegiatan: (1) pengaruh media
tumbuh terhadap pertumbuhan plantlet, (2) pengaruh jarak tanam terhadap
produksi benih G1, dan (3) pengaruh jarak tanam terhadap produksi benih
G2. Rancangan percobaan yang digunakan adalah Acak Kelompok,
dengan perlakuan pada percobaan pertama adalah media dan tempat
aklimatisasi, pada percobaan kedua dan ketiga berupa jarak tanam dan
varietas. Parameter pengamatan meliputi persentase tumbuh, jumlah
batang per rumpun, jumlah buku, diameter batang, dan tinggi tanaman. Hasil penelitian menunjukkan bahwa penggunaan polibag dan pot tray merupakan cara terbaik untuk aklimatisasi tebu. Jarak tanam terbaik benih
G0 dan G1 varietas PS864 dan SS-57 di KP Cibinong adalah 60 cm × 40
cm yang dapat memproduksi budset G1 masing-masing 1,72 dan 1,93 juta
per ha dan benih G2 masing-masing 0,9 dan 1,01 juta per ha. Produksi
budset G2 PS864 di Klari pada jarak tanam yang sama menghasilkan 1,94
juta per ha, sedangkan produksi budset G2 varietas PS881 dan Kidang
Kencana di KP Ngemplak masing-masing mencapai 2,02 dan 2,18 juta per
ha. Sementara itu, produksi terbanyak benih G2 varietas Bulu Lawang dan
PS862 di KP Ngemplak dihasilkan pada perlakuan jarak tanam 100 cm ×
20 cm masing-masing sebanyak 2,44 dan 1,41 juta per ha. Produktivitas
benih tebu hasil kultur jaringan dipengaruhi oleh jarak tanam, lokasi
penanaman, dan varietas tanaman.
Kata kunci: tebu, benih unggul, kultur jaringan, jarak tanam, benih G0,
G1, G2

 
Technoscapes and mediascapes influence on village and city relations in Manggarai, East Nusa Tenggara
Authors: Yuliantari Ans Prawati
Published: June 2020

The development of infrastructure and information technology has a significant impact on the relationship between Ruteng, the capital of the Manggarai district, and the surrounding villages. The mobility of the people between the cities and villages has led to new problems which previously did not have a significant influence. The shrinking of the rural agricultural sector and the development of the informal sector in the city are indicative of the dynamic relationship between the two. In order to see the phenomenon of changes that occur in the relationship between Ruteng and the surrounding villages, a theory of landscapes by Arjun Appadurai is used. Interviews were conducted with two entrepreneurs who employed people from five villages, namely Wae Belang, Pong Murung, Purang, Lando, and Nanu, and ten workers from those villages. Observations and literature reviews were carried out to support and complement the data obtained by the interview method. Technoscape, in the form of physical infrastructure development in rural areas and mediascape in the form of television and radio shows, as well as social media, became a pull factor for migration to Ruteng. Meanwhile, the traditional view in the form of go’et (traditional expressions) and the similarity of culture become the push factors for urbanization to Ruteng.
Ecotourism development based on local community empowerment: A case study in the forest village community institution of Wana Cendana, Dago Village, Bogor Regency
Authors: Abdillah Ligar , Prayogo Dody
Published: June 2020

Forest Village Community Institutions (Lembaga Masyarakat Desa Hutan) generally use forest in the agriculture sector in accordance with instructions and capital support from Perhutani. LMDH Wana Cendana operates in the ecotourism sector without instructions and capital assistance from Perhutani. This study aims to analyze the implementation of empowering local communities (LMDH Wana Cendana) who do not have expertise in the field of forest management and ecotourism. The concept used is the empowerment of local communities and ecotourism with qualitative case study methods, thus promoting the novelty of cases and in-depth interviews with informants who are directly involved in the development of Gunung Dago ecotourism. Some previous research shows that empowerment does not prioritize local communities. The development of ecotourism in Dago Village, which began in 2019, prioritizes local potential and independent learning processes, so that local communities are able to transform ex-mining land into beautiful tourist attractions. The independence of the local community is reflected in its involvement in the ecotourism development process, from planning to implementation. In addition, local communities as managers are able to utilize local knowledge, culture and resources to improve the welfare of members without overruling the rules of forest conservation.
Association of plasma lactate level with 28-day mortality in non-elderly and elderly sepsis patients: A retrospective cohort study based on the MIMIC- Ⅲ database
Authors: Dong Yihua , Miao Xiaoyang , Hu Yufeng , Huang Yueyue , Chen Jie , Lu Yingru , Pan Jingye
Published: June 2020

Purpose: The objective of this study is to assess the clinical usefulness of lactate as a predictor of 28-day mortality and the relationship between lactate and 28-day mortality in non-elderly (<65 years) and elderly (≥65 years) sepsis patients who were admitted to an intensive care unit (ICU).Methods: This retrospective study used the Medical Information Mart for Intensive Care Ⅲ, a publicly available database of ICUs. Prognosis was evaluated using receiver operating characteristic (ROC) analysis. Univariate and multivariable binary logistic regression models were used to identify the association lactate with 28-day mortality. We converted continuous variable lactate into a categorical variable based on tri-segment quantile to explore segmentation effects.Results: The average age of 2848 patients was 68.01 years old, and about 55.40% of them were male. The overall 28-day mortality was 30.41%, and the rate in elderly patients was 65.82%. Among non-survivors, the lactate level was significantly greater for the non-elderly than the elderly. Lactate level was positively associated with risk of 28-day mortality of the non-elderly sepsis patients (p for trend < 0.001), but there was no significant association between lactate level and 28-day mortality in the elderly group (p for trend = 0.830). The association between lactate and 28-day mortality for sepsis patients without liver cirrhosis was stronger than for sepsis patients with liver cirrhosis (OR 1.28 vs. OR 1.10, P =0.027).Conclusion: Increased lactate level is associated with higher 28-day mortality in the non-elderly sepsis patients, but there is no significant association between the lactate level and 28-day mortality in the elderly group.
Management of work-related common mental disorders in general practice: a cross-sectional study
Authors: Rivière Mathieu , Toullic Youenn , Lerouge Patrick , Blanchon Thierry , Leroyer Ariane , Plancke Laurent , Prazuck Thierry , Melchior Maria , Younès Nadia
Published: June 2020

Background: General practitioners (GPs) often manage individuals with work-related common mental disorders (CMD: depressive disorders, anxiety and alcohol abuse). However, little is known about the ways in which they proceed. The aim of this study is to analyze GPs’ management and patterns of referral to other health professionals of patients with work-related CMD and associated factors. Method: We used data from a cross-sectional study of 2 027 working patients of 121 GPs in the Nord – Pas-de-Calais region in France (April – August 2014). Statistical analyses focused on patients with work-related CMD detected by the GP and examined the ways in which GPs managed these patients’ symptoms. Associations between patient, work, GP and contextual characteristics and GPs’ management were explored using modified Poisson regression models with robust variance.Results: Among the 533 patients with work-related CMD in the study, GPs provided psychosocial support to 88.0%, prescribed psychotropic treatment to 82.4% and put 50.7% on sick leave. Referral rates to mental health specialists and occupational physicians were respectively 39.8% and 26.1%. Several factors including patients’ characteristics (occupational and sociodemographic), GPs’ characteristics and environmental data were associated with the type of management used by the GP.Conclusion: Our study emphasizes the major and often lonesome role of the GP in the management of patients with work-related CMDs. Better knowledge of the way GPs manage those patients could help GPs in their practice, improve patients care and be a starting point to implement a more collaborative care approach.
A quantitative assessment of the parameters of the role of receptionists in modern primary care using the work design framework
Authors: Burrows Michael , Gale Nicola , Greenfield Sheila , Litchfield Ian
Published: June 2020

Background Amidst increased pressures on General Practice across England, the receptionist continues to fulfil key administrative and clinically related tasks. The need for more robust support for these key personnel to ensure they stay focussed and motivated is apparent, however, to be effective a more systematic understanding of the parameters of their work is required. Here we present a valuable insight into the tasks they fulfil, their relationship with colleagues and their organisation and their attitudes and behaviour at work collectively defined as their ‘work design’. Methods Our aim was to quantitatively assess the various characteristics of receptionists in primary care in England using the validated Work Design Questionnaire (WDQ) a 21 point validated questionnaire, divided into four categories: task, knowledge and social characteristics and work context with a series of sub-categories within each, disseminated online and as a postal questionnaire to 100 practices nationally.Results Seventy participants completed the WDQ, 54 online and 16 using the postal questionnaire with the response rate for the latter being 3.1%. The WDQ suggested receptionists experience high levels of task variety, task significance and of information processing and knowledge demands, confirming the high cognitive load placed on receptionists by performing numerous yet significant tasks. Perhaps in relation to these substantial responsibilities a reliance on colleagues for support and feedback to help negotiate this workload was reported. Conclusion The evidence of our survey suggests that the role of modern GP receptionists requires an array of skills to accommodate various administrative, communicative, problem solving, and decision-making duties. There are ways in which the role might be better supported for example devising ways to separate complex tasks to avoid the errors involved with high cognitive load, providing informal feedback, and perhaps most importantly developing training programmes.
Transcriptomic analysis reveals hub genes and subnetworks related to ROS metabolism in Hylocereus undatus through novel superoxide scavenger trypsin treatment during storage
Authors: Li Xin , Xueru Liu , Xinyue Pang , Yong Yin , Huichun Yu , Yunxia Yuan , Bairu Li
Published: June 2020

Background: It was demonstrated in our previous research that trypsin scavenges superoxide anions. In this study, the mechanisms of storage quality improvement by trypsin were evaluated in H. undatus. Results: Trypsin significantly delayed the weight loss and decreased the levels of ROS and membrane lipid peroxidation. Transcriptome profiles of H. undatus treated with trypsin revealed the pathways and regulatory mechanisms of ROS genes that were up- or downregulated following trypsin treatment by gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes pathway (KEGG) enrichment analyses. The current results showed that through the regulation of the expression of hub redox enzymes, especially thioredoxin-related proteins, trypsin can maintain low levels of endogenous active oxygen species, reduce malondialdehyde content and delay fruit aging. In addition, the results of protein-protein interaction networks suggested that the downregulated NAD(P)H and lignin pathways might be the key regulatory mechanisms governed by trypsin.Conclusions: Trypsin significantly prolonged the storage life of H. undatus through regulatory on the endogenous ROS metabolism. As a new biopreservative, trypsin is highly efficient, safe and economical. Therefore, trypsin possesses technical feasibility for the quality control of fruit storage.
The Persistence of Child and Adolescence Mental Healthcare: Results from Registry Data
Authors: Dijk Hermien , Freriks Roel , Alessie Rob , Mierau Jochen
Published: June 2020

Background: Previous studies on the persistence of child and adolescent mental healthcare do not consider the role of time-invariant individual characteristics. Estimating persistence of healthcare using standard linear models yields biased estimates due to unobserved heterogeneity and the autoregressive structure of the model. This study provides estimates of the persistence of child and adolescent mental healthcare taking these statistical issues into account.

Methods: We use registry data of more than 80,000 Dutch children and adolescents between 2000 and 2012 from the Psychiatric Case Registry Northern Netherlands (PCR-NN). In order to account for autocorrelation due to the presence of a lagged dependent variable and to distinguish between persistence caused by time-invariant individual characteristics and a direct care effect we use difference GMM-IV estimation. In further analyses we assess the robustness of our results to policy reforms, different definitions of care and diagnosis decomposition.

Results: All estimation results for the direct care effect (true state-dependence) show a positive coefficient smaller than unity with a main effect of 0.215 ( p < 0.01), which indicates that the process is stable. Persistence of care is found to be 0.065 ( p < 0.05) higher for females. Additionally, the majority of persistence of care appears to be associated with time-invariant characteristics. Further analyses indicate that (1) policy reforms only slightly affected persistence of care, (2) results are robust to different definitions of care and (3) persistence of care does not differ significantly across subgroups.

Conclusions: The results indicate that the majority of mental healthcare persistence for children and adolescents is due to time-invariant individuals characteristics. Additionally, we find that in the absence of further shocks a sudden increase of 10 care contacts in the present year is associated with approximately 3 additional care contacts at some point in the future. This result provides essential information about the necessity of budget increases for future years in the case of exogenous increases in healthcare use.
Spatial-temporal mapping of hand, foot and mouth disease in relation to climate factors in Xinjiang, China from 2008 to 2016
Authors: xie ling , Huang Ruifang , Wang Hongwei , Xiao Zhengqing
Published: June 2020

[Objectives]: The study mainly aims to depict the epidemiological characteristics of hand, foot and mouth disease (HFMD) in Xinjiang, China and to evaluate the effects of meteorological factors on the incidence of HFMD and the spatial-temporal heterogeneity of HFMD in Xinjiang under the influence of meteorological factors.[Methods]: With the data from the national surveillance data of HFMD and meteorological parameters in the study area from 2008 to 2016. We first employed GeoDetector Model to examine the effects of meteorological factors on HFMD incidence in Xinjiang, China and to test the spatial-temporal heterogeneity of HFMD risk, and then the spatial autocorrelation was applied to examine the temporal-spatial pattern of HFMD.[Results]: From 2008 to 2016, the HFMD distribution showed a distinct seasonal pattern and HFMD cases typically occurred between May and July, peaking in June, in Xinjiang. The relative humidity, precipitation, air pressure and temperature had more influence than other risk factors on HFMD incidence with explanatory powers of 0.30, 0.29, 0.29 and 0.21(p<0.000), respectively. The interactive effect of any two risk factors would enhance the risk of HFMD and there was a nonlinear enhancement between any two risk factors interactive effect. The spatial relative risks in Northern Xinjiang were higher than in Southern Xinjiang. Global spatial autocorrelation analysis showed a fluctuating trend over the years, the spatial dependency on the incidence of HFMD in 2008, 2010, 2012, 2014 and 2015, the negative spatial autocorrelation in 2009 and a random distribution pattern in 2011, 2013 and 2016.[Conclusion]: Our findings show that the risk of HFMD in Xinjiang showed signiﬁcant spatiotemporal heterogeneity. The monthly average relative humidity, monthly average precipitation, monthly average air pressure and monthly average temperature factors might have stronger relationships on the HFMD incidence in Xinjiang, China, compared with other factors. The differences in climate and latitude between Southern and Northern Xinjiang and their arid and semi-arid geographical environment are part of the reasons why the distribution of HFMD in Xinjiang is different from other temperate continental climatic zones. These associations draw attention to climate-related health issues and will help in establishing accurate spatiotemporal prevention of HFMD in Xinjiang, China.
Changes in Inflammatory Cytokines, Antioxidants and Liver Stiffness after Chelation Therapy in Individuals with Chronic Lead Poisoning
Authors: Teerasarntipan Tongluk , Chaiteerakij Roongruedee , Prueksapanich Piyapan , Werawatganon Duangporn
Published: June 2020

Background Chronic exposure to lead causes lead to accumulate mainly in the liver. In vivo studies have shown that lead toxicity is related to alterations in the inflammatory response. We aimed to evaluate the association between lead poisoning and liver fibrosis as well as the change in the degree of liver fibrosis, levels of inflammatory mediators and glutathione (GSH) after chelation therapy.Methods Workers from a battery factory who were exposed to lead for > 12 months and had a blood lead level (BLL) > 70 µg/dL were enrolled (n=86) in the study. Participants underwent chelation therapy with intravenous CaNa2EDTA for 2 days followed by treatment with oral D-penicillamine for 90 days. The primary outcome was the change in the degree of liver fibrosis, which was presented as liver stiffness (LS) measured by FibroScan®. Secondary outcomes were the changes in the levels of serum GSH and inflammatory mediators such as tumor necrosis factor-alpha (TNF-α), interleukin-1β (IL-1β), and interleukin-6 (IL-6) after chelation therapy.Results Among the 86 participants, there was a positive correlation between the duration of lead exposure and LS (r=0.249, p=0.021). To avoid the confounding effect of obesity-related steatosis, only 70 individuals who had controlled attenuation parameters < 296 dB/m, BMI < 25 kg/m2 and normal waist circumference were included in the interventional analysis. After chelation, the mean LS significantly decreased from 5.4 ± 0.9 to 4.8 ± 1.4 kPa (p=0.001). Similarly, all of the inflammatory cytokines studied significantly decreased after chelation (p<0.001); TNF-α decreased from 371.6 ± 211.3 to 215.8 ± 142.7; the levels of IL-1β decreased from 29.8 ± 1.7 to 25.9 ± 4.3; and the levels of IL-6 decreased from 46.8 ± 10.2 to 35.0 ± 11.9. On the other hand, the mean GSH level increased significantly from 3.3 ± 3.3 to 13.1 ± 3.7 (p<0.001) after chelation therapy.Conclusion The duration of lead exposure was significantly correlated with the degree of liver fibrosis. Chelation treatment was associated with increased levels of GSH and decreased levels of proinflammatory cytokines and could potentially reduce the degree of LS. Trial registration: This study was retrospectively registered and approved by the Thai Clinical Trial Registry (TCTR) on 2019-11-07. The TCTR identification number is TCTR20191108001. http://www.clinicaltrials.in.th/index.php?tp=regtrials&menu=trialsearch&smenu=fulltext&task=search&task2=view1&id=2867
SHiNeMaS : A web tool dedicated to seed lots history, phenotyping and cultural practices
Authors: De Oliveira Yannick , Burlot Laura , Dawson Julie C. , Goldringer Isabelle , Madi Darkawi , Rivière Pierre , Steinbach Delphine , Frank Gaëlle Van , Thomas Mathieu
Published: June 2020

Motivation
In 2005, researchers from the French National Research Institute for Agriculture, Food and Environment (Institut national de recherche pour l’agriculture, l’alimentation et l’environnement, INRAE) started a collaboration with the French farmers' seed network Réseau Semences Paysannes (RSP) on bread wheat participatory breeding (PPB). The aims were: (1) to study on-farm management of crop diversity, (2) to develop population-varieties adapted to organic and low-inputs agriculture, (3) to co-develop tools and methods adapted to on-farm experiments. In this project, researchers and farmers' organizations needed to map the history and life cycle of the population-varieties using network formalism to represent relationships between seed lots. All this information had to be centralized and stored in a database.
Results
We describe here SHiNeMaS (Seeds History and Network Management System) a web tool database. SHiNeMaS aims to provide useful interfaces to track seed lot history and related data (phenotyping, environment, cultural practices). Although SHiNeMaS has been developed in the context of a bread wheat participatory breeding program, the database has been designed to manage any kind and even multiple cultivated plant species. SHiNeMaS is available under Affero GPL licence and uses free technologies such as the Python language, Django framework or PostgreSQL database management system (DBMS).
Conclusion
We developed SHiNeMaS, a web tool database, dedicated to the management of the history of seed lots and related data like phenotyping, environmental information and cultural practices. SHiNeMaS has been used in production in our laboratory for 5 years and farmers' organizations facilitators manage their own information in the system.
Oral prednisolone administration in postoperative period improves results of TKA in patient with severe range of motion limitation – a paired outcome study
Authors: Grzelecki Dariusz , Kowalczewski Jacek , Kordasiewicz Bartłomiej , Sibinski Marcin , Olewnik Łukasz , Marczak Dariusz
Published: June 2020

Background. One of the most common problems related to total knee arthroplasty (TKA) is postoperatively limited range of motion, especially in the most difficult cases. The aim of the study was to assess the influence of oral use of prednisolone in the postoperative period on the final results in a patient after TKA with severely limited postoperative range of motion.Methods. Thirty-two patients (32 knees) with a mean age of 61.2 years were selected from our prospectively-collected data base with severe knee range of motion limitation (rheumatoid arthritis, psoriasis, ankylosing spondylitis, posttraumatic and postoperative osteoarthritis). Prednisolone was administrated in two doses per day (1 mg per kg of body mass) and then the dose was slowly reduced for no more than three months. Results. The prednisolone group demonstrated significantly better results one year after the operation than the non-prednisolone group in terms of range of motion (mean extension 0.5˚ and 3.0˚; p=0.02, mean flexion 100.1˚ and 88˚; p= 0.01), WOMAC (mean 85.0 and 76.8 points; p=0.02) and KSS clinical score (mean 86.9 and 81.7; p=0.001) and KSS functional score (79.3 and 71.0 points; p=0.01). No significant differences were observed between the groups in terms of postoperative systemic and surgical site complications; therefore, no complications could be defined as steroid related. Conclusions. The administration of oral prednisolone for a longer postoperative time in patients with severe preoperative range of motion following TKA significantly improves functional results without steroid related complications at one year follow-up.
Nummular Headache - A case report of a rare entity
Authors: Thomas Davis , Heir Gary M. , Patil Amey G. , Soni Prutha K.
Published: June 2020

The authors have withdrawn this preprint due to author disagreement.
Lessons learned through piloting a community-based SMS referral system for common mental health disorders used by female community health volunteers in rural Nepal
Authors: Bhardwaj Anvita , Subba Prasansa , Rai Sauharda , Bhat Chaya , Ghimire Renasha , Jordans Mark , Green Eric , Vasudevan Lavanya , Kohrt Brandon
Published: June 2020

Objective: The Community Informant Detection Tool (CIDT) is a paper-based proactive case detection strategy with evidence for improving help-seeking behavior for mental healthcare. Key implementation barriers for the paper-based CIDT include delayed reporting of cases and lack of active follow up. We used mobile phones and the structured text messages to improve timeliness of case reporting, encouraging follow up, and case record keeping. 36 female community health volunteers piloted this mobile phone CIDT (mCIDT) for three months in 2017 in rural Nepal. Results: Only 8 cases were identified by health volunteers using mCIDT, and only two of these cases engaged with health services post-referral. Accuracy with the mCIDT was considerably lower than paper-based CIDT, especially among older health volunteers, those with lower education, and those having difficulties sending text messages. Qualitative findings revealed implementation challenges including cases not following through on referrals due to perceived lack of staff at health facilities, assumptions among health volunteers that all earthquake-related mental health needs had been met, and lack of financial incentives for use of mCIDT. Based on study findings, we provide 5 recommendations—in particular attitudinal and system preparedness changes—to effectively introduce new mental healthcare technology in low resource health systems.
Trends and determinants of HIV transmission among men who inject drugs in the Pokhara Valley, Nepal: Analysis of cross-sectional studies
Authors: Hogan Sam , Page Andrew , Ogbo Felix , Dixit Sameer , Rajbhandari Rajesh Man , Rawal Bir , Deuba Keshab
Published: June 2020

Background HIV is a major public health issue around the world, especially in developing countries. Although the overall prevalence of HIV in Nepal is relatively low and the country itself is considered low risk, there are specific sub-populations where the prevalence is far higher than the national average. One of these sub-groups is male injection drug users (IDUs). In order to understand the reasons for the differences in prevalence, a series of socio-demographic, behavioural and knowledge-based risk factors need to be assessed. Methods The study used a series of 7 cross-sectional survey datasets, collected between 2003 and 2017 (N=2,235) to investigate trends in HIV prevalence among male IDUs by key socio-demographic and behavioural and knowledge-based risk factors. A series of logistic regression models were conducted to investigate the association between study factors and HIV in the Pokhara valley, Nepal. Results Overall HIV prevalence has decreased from the levels seen in 2003 (22.0%) and 2005 (21.7%), with the lowest prevalence recorded in 2015 (2.6%), however prevalence has increased in the most recent period (4.9%). A lower risk of HIV was associated with younger age (less than or equal to 24 years compared to greater than 24 years, OR = 0.17, 95% CI = 0.10, 0.31), being married (OR = 1.91, 95% CI = 1.25, 3.02) and shorter duration of drug use (less than or equal to 4 years compared to greater than 4 years, OR = 0.16, 95% CI = 0.09, 0.29). A higher risk of HIV was associated with low (compared to secondary or higher) education level (OR = 2.76, 95% CI = 1.75, 4.36), a lack of addiction treatment (OR = 2.59, 95% CI = 1.64, 4.08), and recent use of unsterilized injection equipment (OR = 2.22, 95% CI = 1.20, 4.11). Conclusion The main determinants which increase the risk of HIV among male IDUs in Pokhara were low education level, a lack of treatment for drug addiction and the recent use of unsterilised equipment. Each of these indicate the need to improve addiction treatment and education programs for intra-venous drug use to aid this at-risk group in avoiding risk-taking behaviours.
An efficient bifunctional electrocatalyst of phosphorous carbon co-doped MOFs
Authors: Du Li , Lv Mengyuan , Liu Dandan , Song Huiyu
Published: June 2020

It is eager to develop high-performance and cheap bifunctional electrochemical catalysts for both of the ORR or OER for the energy crisis and environmental problems. Herein, we report a series of ZIF-derived Co-P-C co-doped polyhedral materials with a well-defined morphology. The optimized catalyst Co/P/MOFs-CNTs-700 exhibited favorable electrochemical activities with the lowest over potential of 420 mV to achieve the current density of 10 mA cm -2 for OER and the half potential of 0.8 V for ORR in 0.1 M NaOH. The performance can be well improved by doping phosphorous resource which greatly changed its morphology. Meanwhile, the doped carbon resources also improve the conductivity, which makes it a promising bifunctional electrochemical catalyst and can be comparable with the commercial electrocatalysts.