bluuebunny/crossref_metadata_2025 huggingface dataset:
Challenges and Experience from UI GreenMetric’s 2nd International Virtual Event
Authors: Sari Riri Fitri , Windiatmaja Jauzak Hussaini , Ramadhianti Sabrina Hikmah
Published: December 2022

UI GreenMetric World University Rankings is a non-profit initiative from Universitas Indonesia that ranks universities around the world based on their commitment and actions towards sustainability. During the ranking process, many universities’ performance in UI GreenMetric has progressed. To increase the performance of each university in UI GreenMetric, universities need to share their sustainability achievement and current condition in a forum. These universities can share information about the implementation of sustainability policies in each university through the International Workshop on UI GreenMetric World University Rankings. Due to the ongoing pandemic and our concerns that the event could ease the spread of coronavirus, this event was being held online. We evaluate the workshop to capture the experience gained in organizing the virtual event. From the topics modeling based on several regions, we conclude that university leaders around the world are very concerned about diverse sustainability issues, alongside the Covid-19 pandemic that has been going on for more than a year. We also conclude that people are getting more accustomed to virtual events, as evidenced by the increase in IWGM 2021 active participants of around 44% compared to 2020 virtual workshops. Keyword: green workshop, sustainability, digital transformation, online workshop, synchronous model, asynchronous model.
Advancing university management during the pandemic of COVID-19 at ESPOCH
Authors: Vaca Byron , Echeverría Magdy , Córdova Rafael
Published: December 2022

The university action to the issues that came along with COVID-19 needed to embrace the whole management system for facing the challenges related to infrastructure, water, waste management, transport, and education. Escuela Superior Politécnica de Chimborazo (ESPOCH) has focused most of its efforts into building and maintaining its infrastructure. The linkage to society has become of paramount importance for ESPOCH, during this time, the university becoming the first and biggest vaccination site in the city. Moreover, several conferences related to training and business ideas for entrepreneurs have been launched, always keeping sustainability in mind. Universal access for people with disabilities and the use of efficient lightning is a common characteristic of all the new buildings; the residues are technically disposed of having managed 4413 m3 of them during 2020. The same technical disposal of residues is applied for recyclable, biodegradable, dangerous and inert ones. Additionally, the campus green areas have been maintained and forested using native species planting about 500 new trees during the last year. The opportunities brought by the pandemic have been harnessed to strengthen the setting and infrastructure of ESPOCH while at the same time serving the surrounding community.Keyword: university management, COVID-19, Latin America, sustainability, higher education.
Ecosystem services of the city campus: carbon landfill of the RUDN-University
Authors: M.M Redina , E.V. Savenkova
Published: December 2022

The approaches to the organization and the first results of the project on the organization of a carbon landfill at the Peoples ' Friendship University of Russia are presented. The topic of the absorption of greenhouse gases by natural ecosystems is one of the most actively developing. A complex of scientific and educational projects on climate change, decarbonization, and assessment of ecosystem services is being implemented at the RUDN University. One of the directions is our own carbon landfill on the campus. The object is of interest as a technologically modified ecosystem that is under the influence of anthropogenic sources. The analysis of ecosystem activity in the absorption of greenhouse gases and, accordingly, the assessment of ecosystem services of this type is implemented using the RUDN's own environmental monitoring network, which has been operating since 2017. Preliminary assessments allowed us to draw conclusions about the degree of transformation of ecosystem components and their contribution to the absorption of greenhouse gases. The project has both practical and educational significance and is considered as part of the package of strategic topics for the development of the university "Campus as a green lab", contributing to the achievement of sustainable development goals. Keyword: carbon landfill, environmental monitoring, RUDN, carbon footprint, ecosystem services
REAP, a project for PET and can
Authors: Velosa Ana
Published: December 2022

In a moment of change, with an impulse from the pandemic that hit the world, the pursuit of the Sustainable Development Goals has become a clear necessity towards a more sustainable world, with less inequalities and a basis for the upbringing of future generations. SDG Goal 12 Sustainable Consumption and Production, 13 - Climate Action - and 14 - Life below water - are clearly linked to plastic and metal consumption and production. Also, Goal 10 - Reduced inequalities - plays its paper in this field. Not only does plastic and metal production, consumption and use need to be reformed, but also producers need to bridge inequalities and reuse, recycle and introduce circular economies in their own countries, not inducing mass imposition of waste in poorer economies. With this in mind, at the University of Aveiro, the REAP Project (Recycling of PET and Aluminium Packages) is being implemented, together with a Norwegian partner, with vast experience in the plastic waste sector. This project will help create the idea of PET and aluminium impact from a tax on these packages inside campi walls and a tax return after adequate deposition. Tracking these numbers and promoting research in the area of PET and aluminium reuse are a further input towards the implementation of SDGs.The paper will explain the project, its goals and ambitions.Keyword: PET, Can, SDG Goals, circular economy
Improving Water Conservation at Universitas Diponegoro, Indonesia
Authors: Budihardjo Mochamad Arief , Arumdani Indah Sekar , Puspita Annisa Sila , Ambariyanto Ambariyanto
Published: December 2022

It is estimated that the amount of water needed by Universitas Diponegoro will increase in the years to come. Several efforts are required to ensure the fulfillment of water needed while also considering its sustainability. There have been studies on water conservation at the industrial level. Still, limited studies have discussed this problem in Indonesia specifically at university level. Therefore, this study discusses the water conservation program at Universitas Diponegoro that might be used as a reference for other universities to address water supply problems. This study aims to discuss in depth water conservation efforts at Universitas Diponegoro. This study incorporates a descriptive-qualitative approach along with direct observation. Some programs on water supply have been implemented in Universitas Diponegoro such as conservation, treated water consumed, water recycling and water-efficiency. The existence of rainwater harvesting tanks (RWH), reservoirs, biopores, wastewater treatment plans (WWTPs) and ponds are among the efforts that have been applied at Universitas Diponegoro in order to conserve the water. To date, Universitas Diponegoro has successfully conserved more than 75% of the water, recycling about >50% of wastewater, installing about >50% of water-saving equipment, and has treated clean water into drinking water using reverse osmosis.Keyword: water, conservation, sustainability, campus
Estimation of Rainwater Harvesting Potential in an Educational Institute of Faisalabad, Pakistan
Authors: Husnain Syed Ali , Tariq Khawaja Adeel , Khan Nouman
Published: December 2022

Pakistan is on verge of facing severe water scarcity issues by 2025. An exponential increase in population increases the water demand as most of the population in the country depends on groundwater. Over extraction of groundwater is causing depletion in the groundwater table at an alarming rate. Water conservation is becoming the need of time. Rainwater Harvesting is one the best methods that can be used to conserve water. This paper aims to determine the total volume of water that can be conserved from Rainfall on the Rooftop at the University of Faisalabad, Amin Campus located in an industrial city Faisalabad, Pakistan. For this purpose, water usage on the campus is estimated. The area of the campus rooftop is measured by conducting a topographic survey. Rainfall data from the year 1981-2021 is collected and average monthly rainfall is calculated. The soil Conservation Service Curve Number method is adopted to calculate the run-off. Results indicated that about 1300 cubic meters of water can be conserved per year which will cover about 20-25 percent of the total water demand of the campus if a Rainwater Harvesting System is installed at the campus.Keyword: Rainwater Harvesting, Water Conservation, Water Scarcity
Shared Spaces and Social Integration
Authors: Dalbelo Thalita Dos Santos , Dieguez Adriana B. , Galante Aline Eid , Romero Gabriela M. , Torniziello Talita M.
Published: December 2022

The pandemic caused by the SARS-COv2 virus demanded actions in universities to ensure safety public health of their community. Several fronts are working in this direction, from physical distancing and sanitation protocols, to the use of indoor and outdoor environments, which includes the circulation of pedestrians and cyclists through the campuses. The University of Campinas is carrying out a tactical urbanism project, consisting of a set of actions aimed at low-cost changes in the built environment to test possible improvements through a living laboratory that involves the entire local community. The living laboratory is an innovative systemic approach that enables the integration of research and innovation in a territorial context through co-creation that involves the local community. The objective of the living laboratory of tactical urbanism at Unicamp is to encourage and guide the circulation of pedestrians and cyclists on the campuses in conditions that ensure physical distance. For this, workshops, questionnaires, decisions and collaborative actions are carrying out, so the community is involved in all stages of the project. After the situational survey and planning, actions should involve surface design with patterns and artistic paintings along the streets in order to promote shared use between modes of transport with special consideration for pedestrians and cyclists. As a result, it is expected that Unicamp will be able to restart face-to-face activities during the pandemic with public safety, mobility and low investment.Keyword: Sustainable Urban Mobility, Pedestrian, Cyclist, Sustainable Campus
Telemedicine and molecular Sars-CoV-2 early detection to face the COVID-19 pandemic
Authors: Cherem José , Pylro Victor Satler , Poles Katia , Carvalho Richardson Costa , Carvalho Ewerton , Santos Juliana Anacleto dos , Barçante Joziana Muniz de Paiva
Published: December 2022

The COVID-19 pandemic brought a series of challenges to the academic community. Social distancing measures imposed the interruption of face-to-face activities besides the implementation of remote work and online classes. For safe and gradual return, the monitoring of individuals, quick detection of infection, contact tracing, and isolation of those infected became essential. In this sense, we developed strategies to face the pandemic at the Federal University of Lavras (UFLA) - Brazil. A Telemedicine Program (TeleCovid) and the assemblage of a laboratory for SARS-CoV-2 molecular diagnosis (LabCovid) were essential measures for monitoring, preventing, and controlling outbreaks at the university. TeleCovid works with a team of students who guide and answer questions regarding COVID-19 and, when necessary, make the referral for online consultation with medical professionals. In the suspicion of SARS-CoV-2 infection, the doctor refers the patient for testing at LabCovid. LabCovid performs the sample collection using nasal swabs, followed by processing samples by the RT-qPCR method. We have placed all positive patients in isolation and tested their contacts. This approach meant that positive cases were identified early, thus avoiding outbreaks in different environments in face-to-face activities.Keyword: Covid-19; university, RT-qPCR
Impact of COVID-19 on achieving the goal of sustainable research and education: case of Volgograd State University
Authors: Cherkasova Oksana , Lebskaia Daria
Published: December 2022

It is of no doubt that the pandemic had and still has a great impact on all the spheres of human activities. The situation has changed the traditional way of life and we have to get used to the new “normality”. Given the unusual and never experienced circumstances, educational institutions all over the world have been forced to establish new ways out and paths to keep the balance and be sustainable. Despite the various obstacles, universities around the globe are still fighting for the SDG 4 and seeking appropriate solutions for achieving this and other goals. Research and education practices have undergone consequential changes which can be positive or negative. In the case of Volgograd State University the authors will try to get the reader acquainted with its best practices that have been implemented to support the students, the faculty and administrative staff during this fluctuating period and go on achieving SDG 4.Keyword: sustainable development, sustainable education, SDG 4, green thinking, green education
Green economy metrics as a promoter of sustainable development in universities. Case study: El Bosque University
Authors: Romero-Infante Jaime Alberto , Ramírez Mónica Sofía Rico , Luna Luz A. , Leguizamon Sergio , Verjel Elissa
Published: December 2022

The exchange that occurs in universities when they participate in international rankings is an important space to share and grow in the academic production of teachers and in the training of students. At the beginning, the sustainable social responsibility system was adhered only to the industry due to the increase in large-scale production; however, the academy has taken a voice and vote on this climate phenomenon. This is why projects aimed at sustainability have been proposed in universities that aim at a green economy. Likewise, the UI Green Metric Rankings allows higher education institutions worldwide to measure their sustainable actions in different categories on a voluntary basis.For this reason, this article presents the best practices of the University El Bosque against the different indicators that the UI Green Metric measures, such as infrastructure, energy and climate change, waste, water, transport and education. Consequently, the concept of sustainability has become a vital element for the development of programs that involve the institution in internationalization through the global recognition generated by being participants and being able to be in the range of green universities.As a conclusion of this exchange, Based on responsible production methods with the natural and social environment or Clean Modalities, a production cycle is proposed that opens the possibility of integrating with other related production systems that receive their waste as raw materials in a network, this is Symbiotic Cycle. To arrive at the approach of a symbiotic disposal of waste as inputs with other production systems in such a way as to consolidate a set of sustainable organizations that collaborate with each other and that continuously recover the value to increase efficiency.Keyword: sustainability, green economy, sustainable development
Potencjał agroekosystemów do naturalnej regulacji liczebności szkodników. Analiza na poziomie krajobrazowym dla Polski
Authors: Łowicki Damian
Published: December 2022

Niewielkie półnaturalne siedliska, zwłaszcza zadrzewienia śródpolne, odgrywają w krajobrazie rolniczym bardzo ważną rolę. Jedną z nich jest zwiększenie oporu naturalnego środowiska na wystąpienie gradacji szkodnika. Funkcja ta wynika z faktu, że zadrzewienia są miejscem bytowania organizmów będących naturalnymi wrogami szkodników upraw, m.in. owadów drapieżnych oraz pasożytów i parazytoidów. W intensywnie zarządzanych krajobrazach rolniczych ochrona roślin uprawnych opiera się w dużej mierze na środkach chemicznych, co zwiększa koszty produkcji i zanieczyszczenie środowiska. Wzmocnienie naturalnej kontroli szkodników może przyczynić się do wzrostu bezpieczeństwa żywnościowego, przy jednoczesnym zmniejszeniu presji na bioróżnorodność i środowisko. Jednocześnie zadrzewienia śródpolne zwiększają efektywność innych usług, takich jak zapylanie czy regulacja klimatu. W ostatnim czasie dokonano znacznych postępów w mapowaniu usług ekosystemowych, ale naturalne zwalczanie szkodników jest jednym z najrzadziej podejmowanych tematów. Niniejsze opracowanie ma na celuprzedstawienie przestrzennej zmienności potencjału i zapotrzebowania na tę usługę, wskazując te części Polski, w których potrzeby ochrony zadrzewień są największe. Zastosowano podejście krajobrazowe, biorąc pod uwagę nie tylko udział zadrzewień, ale także wielkość płatów, ich kształt oraz wielkość strefy ekotonowej. Wyniki oraz wypracowana tu metodyka mogą służyć do formułowania polityk i strategii mających na celu zwiększenie bioróżnorodności i usług ekosystemowych. Badania te mogą być też podstawą działań wspierających zrównoważone rolnictwo, np. poprzez odpowiednią alokację funduszy z Programu Rozwoju Obszarów Wiejskich.
Misprinted Representations in Stoicism
Authors: Pineda Christian
Published: December 2022

This paper deals with the Stoic concept of misprinted representation (φαντασία παρατυπωτική), which has received little attention compared to other concepts of Stoic epistemology and philosophy of mind. I aim at showing that a better understanding of this concept is important for grasping some elements of the Stoic account of mental representations that have been ignored or misunderstood in modern Stoic scholarship. First, by clarifying the status of the misprinted representation as a genuine representation, we can understand what it means (and does not mean) to say, from the Stoic point of view, that the intentional object of a representation is the external object that caused it. Second, by understanding this issue, we obtain some resources to deal with the ambiguity of the preposition ἀπό in the definition of cognitive representation. Thus, the concept of misprinted representation proves to be important for appropriately understanding the Stoic concepts of representation and cognitive representation.
Smooth complex projective rational surfaces with infinitely many real forms
Authors: Dinh Tien-Cuong , Oguiso Keiji , Yu Xun
Published: December 2022

We construct a smooth complex projective rational surface with infinitely many mutually non-isomorphic real forms. This gives the first definite answer to a long-standing open question if a smooth complex projective rational surface has only finitely many non-isomorphic real forms or not.
Lithofacies discrimination using seismic anisotropic attributes from logging data in Muglad Basin, South Sudan
Authors: Deng William A. , Hwang Seho , Jang Seonghyung
Published: December 2022

The identification of formations in anisotropic reservoirs using seismic reflection data and logging data may lead to misrepresentations of the actual formations. Lithofacies discrimination intrinsically has ambiguity, and the depositional sequences of the study area comprise shales, fine-grained sands, and silts. So it needs to reduce the uncertainty of the lithofacies discrimination using anisotropic parameters. This study proposes an approach involving seismic anisotropic parameters to discriminate between different lithofacies. We calculate four anisotropic parameters (ε, δ, γ, η) from logging data (V
p, V
s, and density) and then employ these for lithofacies discrimination. We compared our results to lithofacies discrimination based on traditional parameters such as V
p/V
s ratio, clay volume, and water saturation. Using field data from Muglad Basin in South Sudan, we show how the suggested parameters could be used to identify eleven zones with distinct lithofacies. According to the anisotropic parameters, the lithofacies discrimination results are similar to other logging data, and it is easier to separate the lithofacies than petrophysical data. Furthermore, we introduce a new parameter, i.e., the difference between the normalized anisotropic δ parameter and clay volume, which can be used as a possible indicator for heavy oil reservoirs. The new parameter matches well with water saturation in the field data application.
Politics behind the law: unveiling the discursive strategies in extradition hearings on Meng Wanzhou
Authors: Cheng Le , Liu Xiuli
Published: December 2022

Deciphering the hidden political implications in legal discourse has become hot foci in the study of international politics to unravel the political roles and positionings of various stakeholders in law as well as its enforcement and adjudication. Drawing on CDA approach, this study provides a text mining of 12 extradition hearings on Meng Wanzhou case. The findings of the present study indicate that the case is in the name of law but actually with the nature of politics in the context of the U.S.–China trade war. It also demonstrates evidence of manipulation of political power and reframing of the event occurrences throughout the texts of the 12 hearings, by exerting the repetitive use of a bundle of legal discursive strategies. The violation of justice and equality in the legal discourse around the present case is based on the superior status of the U.S. in contrast with Canada in the discursive practices as well as the political contemplation of Canada, resulting in challenges to the fundamental principles of rule of law around the world. This research furthers the understanding of the strategies and entanglement of justice and injustice, power and control in the process of discourse construction.
Synchronous triple primary malignant tumours in the bladder, prostate, and lung harbouring TP53 and MEK1 mutations accompanied with severe cardiovascular diseases: A case report
Authors: Li Zhi-Ke , Zhao Qiang , Li Ning-Fu , Wen Jing , Tan Bang-Xian , Ma Dai-Yuan , Du Guo-Bo
Published: December 2022

Although the incidence of multiple primary malignancies (MPMs) is increasing, synchronous triple primary malignant tumours with prostate, bladder and lung is rarely reported. Gene mutation is thought to be a reason for MPMs, and severe cardiovascular diseases may interrupt the cancer treatment. Here we reported a 64-year-old male patient with synchronous triple primary malignant tumours of the bladder urothelial carcinoma, prostate adenocarcinoma, and non-small cell lung cancer (NSCLC) with mutations in TP53 and MEK1, all the three malignancies were diagnosed within 10 days. Although being interrupted by severe cardiovascular diseases (including myocardial infarction, venous thrombosis, and aneurism of the aortic root), he was successfully treated with radical cystoprostatectomy, chemotherapy plus pembrolizumab (a PD-1 antibody), and radiotherapy of the lung lesion, followed by maintenance monotherapy of pembrolizumab, overall survival was more than 26 months. In conclusion, a patient of synchronous triple primary malignant tumours with prostate, bladder, and lung harbouring TP53 and MEK1 mutations accompanied with severe cardiovascular diseases was treated successfully, which may suggest that comprehensive treatment, especially radical treatment such as operation and radiation, is very important for MPMs.
Počátky rozvoje letecké dopravy v Krkonoších a blízkém okolí
Authors: Kocián Pavel
Published: December 2022

The study contemplates the expansion of transport aviation in the Krkonoše region and their immediate surroundings from 1913 until the end of the 1940s. The activities of DELAG, CFRNA/CIDNA, DLH and ČSA are mentioned as well. A substantial part of the text is also devoted to accidents or landings in the field that occurred in the region during air transport.
Architectura natural, the Unpublished Fourth Volume of Juan Caramuel’s Seventeenth-Century Architectural Treatise
Authors: Navarro Morales Maria Elisa
Published: December 2022

Architectura civil recta y obliqua (1678–79), by the Cistercian Juan Caramuel de Lobkowitz (1606–82), is one of the most important Spanish architectural treatises of the seventeenth century. The work was published in three volumes, and until recently, scholars knew of an unpublished fourth volume, Architectura natural, only through a fragment of sixty pages titled Compendio de architectura natural. In her Findings article Architectura natural, the Unpublished Fourth Volume of Juan Caramuel’s Seventeenth-Century Architectural Treatise, Maria Elisa Navarro Morales presents more than two hundred manuscript pages unearthed at the episcopal archive in Vigevano. This research not only proves that Caramuel intended to publish an additional volume but also critically expands our knowledge of his treatise by underscoring the vital importance of an understanding of the natural world for architectural education. This challenges our contemporary emphasis on professional specialization and invites us to rethink how architecture was viewed in the early modern world.
Nationalizing the International Style
Authors: Dianat Alborz
Published: December 2022

In Nationalizing the International Style: The Formation of British Identity in the Architectural Criticism of P. Morton Shand, Alborz Dianat considers the critical role played by architectural journalist P. Morton Shand (1888–1960) in the debate that took place in the interwar period as British architecture grappled with the seemingly irreconcilable ideas of nationality and modernity. Drawing on an archive of correspondence only recently made public, Dianat shows how Shand assumed a position of leadership in efforts to nationalize architectural modernism in Britain. Shand’s journalistic output contributed to a broader movement calling for a return to Georgian precedents alongside international models, and British architects heeded that call. Shand promoted a new identity for British architecture internationally through his formal and informal networks, and Britain’s leading role in architectural discourse into and beyond World War II was bolstered by his work.
A Refusal to Be Cool
Authors: Melonas Desireé R.
Published: December 2022

On July 1, 1968, closely following the assassination of Martin Luther King Jr., Esquire magazine published an interview with James Baldwin. At the very start of this interview, soliciting Baldwin’s view on the state of race relations in the United States, the editors of the magazine asked him rather straightforwardly: “How can we get the black people to cool it?” Baldwin responded without hesitation: “It is not for us to cool it.” I argue that this accusation-framed-as-question is an example of what philosopher Lewis Gordon calls a theodicean grammar, which refers to the way one expresses the belief that something or someone possesses god-like qualities or is, in actuality, a god. The result of adopting such a standpoint is that when problems arise, the deified being(s) evade responsibility, for it is presumed that “god” in its perfection cannot have imperfections. Against this view, it appears, then, that the responsibility for dealing with problems inherent in a given system, structure, or society rests squarely with those experiencing or having called attention to the issues at hand. Through a close read of this interview, I examine how the Esquire editors’ queries to Baldwin and his treatment of the question of race in the United States reveal the theodicizing evident in misrecognizing/mislocating the sources of black people’s suffering.
Osilodrostat in Cushing’s disease: the management of its efficacy and the pitfalls of post-surgical results
Authors: Antonini Simone , Brunetti Alessandro , Zampetti Benedetta , Boeris Davide , Saladino Andrea , Cesare Cozzi Renato
Published: December 2022

Osilodrostat is a novel, orally administered cortisol synthesis inhibitor, approved in 2020 by the European Medicines Agency (EMA) for the treatment of Cushing’s syndrome in adults. A significant amount of the studies currently available in the literature focus on treatment in patients with Cushing’s disease. However, data collected from patients treated with osilodrostat in real-life settings still represents a small entity. For this reason, in this article, we will discuss two real-life cases of patients with Cushing’s disease treated with this drug. The first report is about a 35-year-old woman with an adrenocorticotrophic hormone (ACTH)-secreting adenoma. After non-curative trans-nasal-sphenoidal (TNS) surgery, due to a small remnant of the adenoma, medical therapy with osilodrostat achieved fast and effective biochemical and clinical response. During treatment, progressive increase of ACTH levels and an enlargement of the pituitary remnant were documented, with planned radiosurgical treatment. The second case reports a 32-year-old man diagnosed with Cushing’s disease in 2020, who, after surgery refusal, started osilodrostat at progressively up-titrated doses, according to 24 h urinary free cortisol levels, up to 5 mg twice a day. With osilodrostat, the patient reached biochemical and clinical control of disease until TNS surgery in October 2021, with complete remission. The first post-surgical biochemical assessment was equivocal in spite of a transient clinical hypoadrenalism, reverted after 2 months with the restoration of physiological hypothalamic-pituitary-adrenal axis (HPA) function.

Learning points

Osilodrostat is a potent oral drug viable for Cushing’s disease as medical therapy when surgery is not feasible or remission cannot be reached.

Osilodrostat proves to be a safe drug and its main adverse effect is hypoadrenalism, due to the adrenolytic action of the compound.

Osilodrostat needs a very tailored approach in its clinical use because there is no correlation between the level of hypercortisolism pre-treatment and the dose required to reach disease control.
45,X male – rare case of unbalanced translocation of Y chromosome to chromosome 2 presenting with developmental delay, learning difficulty and obesity
Authors: Suntharesan Jananie , Apperley Louise , Senniappan Senthil
Published: December 2022

A male phenotype accompanied by a 45,X karyotype is rare. It may occur due to Y chromosomal translocation or insertion to X/autosome. Clinical presentation may vary depending on the presence of the Y chromosomal locus and the degree of loss of autosome material. 45,X males can present with short stature and Turner syndrome phenotype due to haploinsufficiency of genes which are normally expressed in both X and Y chromosomes. The presence of the sex-determining region Y (SRY) gene leads to the differentiation of bipotential gonads to testis. Most individuals go through puberty normally, but some may need pubertal induction for delayed puberty. Rarely some can have a pubertal arrest. The risk of gonadoblastoma is minimal in these individuals due to functioning testicular tissue. The azoospermia factor (AZF) region is found on the long arm of the Yq chromosome and is needed for spermatogenesis. In a 45,X male with unbalanced translocation of Y chromosome, spermatogenesis can be affected due to the lack of AZF leading to Sertoli cell-only syndrome. This will have an implication on fertility in adult life. We present a 14-year-old boy with developmental delay, learning difficulties and subtle dysmorphic features who was diagnosed with 45,X,der(2)t(Y:2)(?:p25). Fluorescence in situ hybridisation analysis revealed translocation of SRY (Yp11.3) to the terminal part of the short arm of chromosome 2 resulting in the deletion of most of the Y chromosome (Yp11.2-q12) and part of chromosome 2(2p25.3). This is the first case where SRY translocation to chromosome 2 presents with the above clinical presentation.

Learning points

45,X karyotype is rare in male.

It may occur due to SRY translocation or an insertion to X/autosome.

SRY gene translocation to chromosome 2 has been not reported in the literature.

Clinical presentation can be varied due to degree of loss of chromosomal material.

Due to loss of AZF region found on the long arm of the Yq, spermatogenesis can be affected. Loss of 2p25 leads to learning difficulty and obesity.
Ellagic acid could prevent experimentally induced oxidative stress in rats
Authors: Kisacam Mehmet Ali , Ozan Kocamuftuoglu Gonca , Ozan Enver , Temizer Ozan Sema
Published: December 2022

Amaç: Dietilnitrozamin (DEN) ve fenobarbital (PB), metabolizması sırasında reaktif oksijen türlerini (ROS) üretilmektedir. Ellagik asit (EA), antioksidan aktiviteye sahip, biyolojik olarak aktif, doğal bir polifenoldür. Bu çalışma, sıçanlarda DEN-PB'nin neden olduğu karaciğer hasarı üzerinde EA'nın önleyici ve koruyucu etkilerini değerlendirmek için yapılmıştır.

Gereç ve Yöntem: 60 yetişkin Sprague-Dawley sıçan 6 gruba ayrıldı: Negatif kontrol, DEN, EA, DEN-PB (pozitif kontrol), DEN-PB-EA (tedavi) ve EA-DEN-PB (ön tedavi). DEN, pozitif kontrol, tedavi ve ön tedavi gruplarına 150 mg/kg DEN verildi. İki hafta sonra pozitif kontrol ve tedavi gruplarına 500 ppm PB uygulandı. EA ve ön tedavi gruplarına 50 mg/kg/gün EA oral yolla sekiz hafta ve tedavi grubuna ise dört hafta boyunca günaşırı verildi. Sekiz hafta sonra sıçanlar dekapite edildi, karaciğer ve kan biyokimyasal değerlendirmeye tabi tutuldu.

Bulgular: DEN’in tek başına veya PB ile birlikte karaciğer MDA düzeylerini önemli ölçüde arttırdığı; ancak plazma MDA seviyelerini değiştirmediği görüldü (p<0,001). EA ön tedavisi, karaciğer MDA seviyelerini azalttı. CAT aktivitesinin, pozitif kontrol grubunun karaciğer ve eritrositlerinde değişmediği belirlendi. Karaciğer CAT aktivitesi, ön tedavide önemsiz ve tedavide ise anlamlı olarak arttı (p<0,05). SOD aktivitesi, DEN ve pozitif kontrol gruplarının karaciğer ve eritrositlerinde değişkenlik göstermedi. EA, karaciğer SOD aktivitesini önemli ölçüde arttırdı (p<0,001). Tek başına veya PB ile birlikte DEN uygulaması hem karaciğer hem de kan GSH düzeylerini önemli ölçüde düşürürken (p<0,05), EA uygulaması tedavi grubunda karaciğer GSH düzeylerini arttırdı (p<0,05). Tedavi grubunda kan GSH seviyeleri önemli ölçüde azaldı (p<0,001).

Öneri: EA koruyucu tedavisinin, sıçanlarda DEN ve PB kaynaklı karaciğer oksidatif stresinde EA tedavisinden daha etkili olabileceği düşünülmektedir.

Anahtar kelimeler: Dietilnitrozamin, ellagik asit, fenobarbital, oksidatif stress
Effects of selected factors on spruce dowel joint stiffness
Authors: Záborský Vladimír , Kamboj Gourav , Sikora Adam , Borůvka Vlastimil
Published: December 2022

Joints are used to join furniture parts, and they represent a critical part of the structure of furniture. The quality of joints is greatly affected by the accuracy of their execution. When designing furniture, it is important to carefully consider the type of joint used so that it can hold all the joined elements together. Under loading of the joined structures, internal forces develop, which can lead to failure of the joints. This study investigated the elastic stiffness of spruce (Picea abies L.) dowel joints. The effects of selected factors such as the type of loading (compressive versus tensile), the size of the dowels (one-half versus one-third of the thickness of the joined elements), the type of adhesive used (polyvinyl acetate versus polyurethane), and annual ring deflection were examined. Spruce dowel joints exhibited the highest elastic stiffness values with a higher-diameter dowel glued with PUR adhesives and subjected to compressive loading. The impact of annual rings was not a significant factor. Finally, the reference type joints were compared with other commonly used types, such as three types of mortise and tenon joints (simple, haunched, and dovetail).
Photometric method for determing degradation surface of a geostationary object
Authors:   Astronomical Observatory of the I. Mechnikov Odessa National University, Sukhov P. P. , Sukhov K. P. ,   National Space Facilities Control and Testing Centre, Space Observation Center, Pavlovskyi A. L. ,   National Space Facilities Control and Testing Centre, Space Observation Center, Mamray S. A. ,   National Space Facilities Control and Testing Centre, Space Observation Center
Published: December 2022

We propose a new method of using photometric data for determining the degradation of the optical parameters of the GSS surface since the GSS’s active operation in orbit. Experimental data on changes in the coefficients of spectral reflection (degradation) of the surface of several geostationary satellites with different types of space platforms over several years are presented. Data were obtained from ground-based photometric observations in filters B, V, and R. Among studied satellites, there are „Astra 2E” (bus Eurostar-3000), „Azerspace 2/Intelsat 38” (bus SSL-1300), „Sicral 2” (bus Spacebus-4000B2), „Сosmos 2520/ Blagovest 11L” (bus Ekspress-2000). It was revealed that the nature of the change in the surface reflectivity for the different satellites differs. Space materials on the surface of geostationary satellites manufactured in the second decade of the 21st century demonstrate that their surface is more resistant to the aggressive space environment than that of the satellites manufactured in the late 20th century. Methods for determining the type of space material and its color in different spectral bands using multicolor photometric observations are proposed. As a continuation or addition to the laboratory method, the authors propose to use the results of ground-based multicolor photometric observations to determine the degree of degradation of the spacecraft’s surface.
Digital literacy, remote teaching and access during COVID-19 pandemic: Impacts on postgraduate female in Brazilian Amazon
Authors: Silva Cícero da , Komesu Fabiana , Fluckiger Cédric
Published: December 2022

The aim of this article is to understand how digital literacies, the usage of digital technologies and emergency remote teaching during the COVID-19 pandemic have affected the life of women participating in stricto sensu Graduate Programs of Universities in the Brazilian Legal Amazon. This study is based on the perspective of digital literacies, which considers the social uses of reading and writing. This is a mixed approach, exploratory and applied research. The data has been collected during August and September, 2021, by means an online platform, based on a 30-item semi-structured questionnaire. The data set comprises 218 valid answers from female professors (n = 100) and students (n = 118) (age 18+) of the surveyed Universities. The results show that the respondents have faced many challenges in emergency remote teaching during the pandemic, in particular, work overload, scarce interaction with colleagues, limitations in the use of digital technologies, difficulties in accessing digital technologies, mental/physical health problems and lack of boundaries between academic and family activities performed in the household environment. Nonetheless, the digital technologies have enabled them to participate in events (livestreams, webinars, conferences, courses), meeting research groups and proceed with classes and research. In a geographically large and economically disadvantaged region, as is the case of the Brazilian Legal Amazon, public policies are essential in order to promote literacy events and activities.
Students’ Perceptions of Ethics in Applied Linguistics Research at a Costa Rican Public University
Authors: Charpentier-Jiménez William
Published: December 2022

This article examines students’ perceptions of ethics and ethical training in research on second language acquisition. The role of ethics in applied linguistics and research has received little attention, despite its relevance. This study, which was conducted from May to June 2022, involved 26 TESOL students enrolled in a Licenciatura program at a Costa Rican public university. It used a quantitative, direct needs assessment design. The researcher collected data through a survey designed to elicit students’ opinions on this issue. Quantitative data were analyzed using descriptive statistics. Data analyses indicate that: 1) students tend to reject unethical behaviors in research (68.75%); 2) some behaviors seem more permissible than others; 3) students consider ethics an essential component of research (x̅ = 4.6, SD = 0.57, Mod = 5); and 4) the Licenciatura program does not incorporate a systematic approach to ethical training in SLA research (X̄ = 9.33; SD = 8.08. Consistent with the reviewed literature, these findings demonstrate the lack of ethical training in language teaching programs and second language research. Furthermore, the analysis suggests that direct instruction may broaden students’ understanding of ethical issues when conducting research. Finally, these findings suggest that students would greatly benefit from a more structured curriculum that considers the ethical component of research.
Convex Polygons and Separation of Convex
Authors: Rivera-Campo Eduardo , Urrutia Jorge
Published: December 2022

We prove that for any collection F of n ≥ 2 pairwise disjoint compact convex sets in the plane there is a pair of sets A and B in F such that any line that separates A from B separates either A or B from a subcollection of F with at least n/18 sets.
Las anomalías precoces de la continuidad en el discurso constituyen biomarcadores predictivos de psicosis
Authors: Figueroa-Barra Alicia-I. , León-Bustos María-Elena , Gaspar-Ramos Pablo
Published: December 2022

El lenguaje se está sistematizando como área de pesquisa clínica porque contiene características que funcionan como un biomarcador para la predicción de psicosis. El objetivo del estudio fue contrastar dos tipos de características de continuidad discursiva entre personas que cursan Estados Mentales de Alto Riesgo (CHR) y personas con diagnóstico de esquizofrenia. Nos referimos, por una parte, a características referenciales, tales como conexión, iteración y distancia referencial, y, por otra, a las de fluidez verbal, entendida como la presencia de pausas aberrantes. Se analizaron entrevistas clínicas de 10 pacientes diagnosticados de esquizofrenia, 10 CHR y 10 controles sanos. Para el análisis de la referencialidad se seleccionaron ventanas de oraciones y para la fluidez verbal se consideraron 15 minutos de habla. Los resultados apuntan a que existe presencia de anomalías en referencialidad y en fluidez verbal entre la población CHR. Dichas similitudes se dan en cuanto a ocurrencia y similitud respecto a las del grupo con esquizofrenia, lo que refrenda nuestra hipótesis de que constituyen biomarcadores predictivos.
«Gracias por vuestra acogida y por vuestro esfuerzo». Los actos de agradecimiento dirigidos a las asociaciones de pacientes con enfermedades poco frecuentes
Authors: Bañón-Hernández Antonio-M.
Published: December 2022

Los libros de firmas constituyen un material muy interesante para estudiar, cuantitativa y cualitativamente, el discurso de valoración positiva dirigido hacia los colectivos de pacientes. Hemos accedido a uno de ellos, para analizar preferentemente los actos de agradecimiento (n = 145). También hemos incluido, en menor medida, datos e interpretaciones sobre actos de presentación e identificación (n = 376), actos descriptivo-valorativos (n = 36) y actos de compromiso (n = 32). El estudio demuestra la importancia de las emociones entre las causas del agradecimiento, en detrimento de los contenidos científicos del macroevento analizado. La estructura preferida de los agradecimientos es la formada por núcleo independiente o por núcleo más especificador (con o sin intensificación). Se concede poca relevancia a los destinatarios. Por otra parte, sorprende la escasez de actos de compromiso. Y los autores de los mensajes demuestran un conocimiento básico sobre las enfermedades poco frecuentes pero también se aprecian carencias y errores fundamentales.
Buscando un castillo altomedieval entre la vegetación. El caso de Castro Valente (Padrón, Galicia)
Authors: Fernández-Pereiro Mario , Sánchez-Pardo José-Carlos
Published: December 2022

El estudio del fenómeno de la forti _cación posromana está surgiendo con interés para el territorio de la antigua provincia romana de Gallaecia. En los últimos años se han realizado importantes progresos en la localización y estudio de estos yacimientos encuadraos en la transición del estado romano a la Alta Edad Media. La combinación de técnicas no invasivas con la excavación arqueológica permite ampliar la información relativa a estos recintos for tificados. En el presente texto se presenta una revisión del proceso metodológico de estudio del yacimiento de Castro Valente (Padrón, Galicia).
El Paisaje Altomedieval de la Sierra de Guadarrama a través de dos casos de estudio: Cancho del Confesionario y la Dehesa de Navalvillar
Authors: Berrica Silvia
Published: December 2022

En el estudio de la formación del Paisaje Altomedieval, se examinaron una serie de yacimientos en la Sierra de Guadarrama (Madrid, España) caracterizados por asentamientos en altura, iglesias, monasterios, poblados y aldeas. Las realidades rurales del Paisaje Altomedieval re_ejaban la explotación, producción y administración de los entornos serranos. Para comprender las realidades sociales de este período y cómo se conectan estos centros, ha sido fundamental el análisis de dos casos de estudio: Cancho del Confesionario y la Dehesa de Navalvillar.
Castillo de Aitzorrotz (Eskoriatza-Gipuzkoa). Análisis histórico arqueológico sobre la evolución del castillo desde su origen hasta su abandono (siglos V-XV)
Authors: Sagredo Iñaki
Published: December 2022

Este artículo expone una panorámica histórica una vez que se han podido constatar todas las fases de ocupación analizadas tras las intervenciones arqueológicas recientes (2009-2018). Como apoyo a dicho estudio se han añadido al registro arqueológico más de treinta dataciones radiocarbónicas en los sectores que presentaban menos alteraciones y de evidencias constructivas. Con todo, se ha podido constatar un origen de uso de este reducto en el siglo V d. C. Dato sin duda que permite abrir una nueva perspectiva en la investigación de las forti_- caciones norte peninsulares.
The incidence of obesity among children in Turkey – obesity awareness, physical activity and other associated factors
Authors:   Nursing Department, Faculty of Health Science, Zonguldak Bülent Ecevit University, Zonguldak, Turkey, Topan Aysel , Ocakcı Ayse Ferda ,   Nursing Department, Faculty of Nursing, Koç University, Istanbul, Turkey, Ayyıldız Tulay Kuzlu ,   Nursing Department, Faculty of Health Science, Zonguldak Bülent Ecevit University, Zonguldak, Turkey, Kurt Aylin ,   Nursing Department, Faculty of Health Science, Bartın University, Bartın, Turkey, Ozdemir Sümeyye ,   Nursing Department, Faculty of Health Science, Zonguldak Bülent Ecevit University, Zonguldak, Turkey
Published: December 2022

Introduction and aim. Obesity is the leading one among the most common nutritional disorders seen during childhood period. We aimed to determine the incidence of obesity, obesity awareness, physical activity and associated factors in school-age children. Material and methods. The sampling was composed of 725 students who were studying in secondary schools during the 2016–2017 academic year. Data were collected with “Personel Information Form”, “Obesity Awareness Scale” and “Physical Activity Questionnaire for Older Children”. The mean age was 12.30±1.32 (10–15), 53% of the students were females and 60.1% of students have a person with obesity in the family. Results. We determined that 18.3% of the students were with obesity. The body mass index of students who have a balanced diet compared to those who have not is statistically significantly lower (p<0.05). There was a significant relationship between students’ body mass index and obesity awareness (r=-0.084, p=0.024). Conclusion. Screening for obesity and related factors, such as obesity awareness, having a balanced diet should begin in school-aged children for childhood obesity prevention.