bluuebunny/crossref_metadata_2025 huggingface dataset:
VBL Collaborative: An Approach for Teaching Complex Transmission Line Problem Statements
Authors:   Department of E&TC Engg, Walchand Institute of Technology, Solapur, Maharastra, India, Mergu Dr. Rohini R. , Shelke Dr. Rupali J. ,   Department of E&TC Engg, Walchand Institute of Technology, Solapur, Maharastra, India, Shetgar Mrs. Piyusha S. ,   Department of E&TC Engg, Walchand Institute of Technology, Solapur, Maharastra, India, Thalange Dr. Asha V. ,   Department of Electronics Engg, Walchand Institute of Technology, Solapur, Maharastra, India
Published: April 2024

Abstract— The educator's choice of techniques is intended to foster a strong love of learning. The different methods of learning can improve learners' abilities. The need of pupils to learn cannot be met by only conventional teaching. When pupils graphically answer the provided question, this is clearly seen. This paper studied students’ performance for the graph based topic ‘Smith Chart’ for the course ‘Radar and Microwave Engineering’ for the third year of engineering students. Total 64 students of the same class considered for the experiment. Video based learning (VBL) is methodology is used in this paper. Total 64 students learn the said chart (Smith Chart) through videos. VBL along with collaborative approach is carried out for experimental group. The two group posttest is carried out. The two group post test results presented in the paper. The assessment is carried out w.r.to Learning Outcomes (LO) and Bloom’s Level (BL). The objectives of the study are to introduce and make students understand Smith chart (BL: Understand, LO1); to determine transmission line parameters and impedance along the line (BL: Apply, LO2); to examine the effect of load variations on transmission line parameters. (BL: Analyze, LO3). The results w.r.to LOs and BL are presented in this paper for both control and experimental group. To assess the level of effectiveness of the intervention feedback is taken from experimental group. Almost 96% students liked the activity. Keywords— smith chart; transmission line; LO; BL; VBL
Improving Student Performance through Interactive Webinars
Authors:   Assistant Professor, Department of Civil Engineering, K.E.S., Rajarambapu Institute of Technology, Rajaramnagar, Post. Sakharale, Tal.Walwa, Dist. Sangli, MS, India, Pin: 415414., More Sachin K. , Patil Yashawant M. ,   Assistant Professor, Department of Civil Engineering, K.E.S., Rajarambapu Institute of Technology, Rajaramnagar, Post. Sakharale, Tal.Walwa, Dist. Sangli, MS, India, Pin: 415414., Kumbhar Popat D. ,   Associate Professor, Department of Civil Engineering, K.E.S., Rajarambapu Institute of Technology, Rajaramnagar, Post. Sakharale, Tal.Walwa, Dist. Sangli, MS, India, Pin: 415414.
Published: April 2024

Abstract— In the rapidly evolving landscape of education, the integration of technology has proven to be instrumental in reshaping traditional learning paradigms. This paper delves into the realm of improving student’s performance by harnessing the potential of interactive webinars as on innovative educational tool. The paper aims to investigate the impact of interactive webinars on student engagement, knowledge retention and overall academic achievement in the course. The findings of the study provide empirical evidence that interactive webinars positively influence student performance. The analysis demonstrates that students who actively participate in interactive webinars exhibit higher levels of comprehension, engagement and retention compared to conventional classroom instructions. The students’ engagements in the webinars are monitored by MOODLE activities, question answer sessions and their quick notes. The comparative graph of pre-test and post-test clearly describe that, there is improvement and shifting of students from CD, DD & FF grade to AA, AB, BB & BC grade. Employing a mixed-methods approach, the research draws upon quantitative data from pre and post webinar assessment, as well as qualitative insights obtained from student surveys and interviews. These methods enable a comprehensive evaluation of the effectiveness of interactive webinars in comparison to traditional instruction methods. In addition to that incorporating industry resource persons into educational activities like interactive webinars can significantly enhance the learning experience of the students. Industry professionals bring real-worlds insights, practical knowledge and helping bridge the gap between academic theory and practical application. Keywords— Interactive Webinar, Industry Resource Person, Student Performance, Industry Practices.
Evaluating Student Attitudes and Behaviors through SEAL to Achieve Holistic Development in Engineering Education
Authors:   Department of Computer Science and Engineering, Thiagarajar College of Engineering, Madurai-625015,Tamilnadu, India, sri R. Leena , Bhavani G. ,   Department of Computer Science and Engineering, Thiagarajar College of Engineering, Madurai-625015,Tamilnadu, India
Published: April 2024

Abstract--Education in engineering not only focuses on knowledge and technical skills but also ensures equal importance to the personal and interpersonal skills. It should also place a strong emphasis on guiding students' behaviors and attitudes, which are crucial for their development as professionals and contributions to society. While engineering education often device assessment strategies on cognitive and psychomotor skills it might be difficult to evaluate and improve emotional and attitudinal aspects. This article proposes a Social Emotional (SE) cum Active Learning (SEAL) pedagogical strategy to cult this gap and experimented for its succession among Vernacular, Vocational and non-computer background students admitted in the academic year of 2019 in computer science engineering department. Various domains such as CDIO (Conceive, Design, Implement, and Operate) framework, the Affective Domain of teaching, Social and Emotional Learning (SEL) are all considered on devising SEAL, and a list of planned activities from the first to the end of semester is recommended for long term behavioral monitoring and assessment. The SEAL is exercised to gauge and improve students' behavioral attitudes, which will help them in their personal, professional, and academic lives through the suggested key performance indicators (KPI). The indicators are self-awareness, self-management, social awareness, Relationship (inter personal) skills and Decision Making. KPI are mapped along with activity based Learning strategies conducted in theoretical and practical courses. The effectiveness of the suggested strategy in enhancing students' development, selfconfidence, and job prospects has been experimentally verified. This comprehensive approach aims to foster students' emotional intelligence, interpersonal abilities, and general well-being while also supporting their cognitive growth. In order to obtain a wellrounded education, the article emphasizes the significance of taking into account of Graduate Attributes such as Knowledge, Skill and Affective domains. This study ardently promotes experimental activities that harmonize academic accomplishments with students' behavioral outlooks, thereby achieving comprehensive program outcomes. It further furnishes a viable pathway to assess student attitudes and behaviors throughout their academic duration.Importantly, while cognitive domains receive considerableImportantly, while cognitive domains receive considerable attention, equal emphasis on the affective domain and the cultivation of social-emotional learning is essential for holistic development was the motive for designing SEAL. Keywords: Activity Based Learning; Engineering Education; Social Emotional Learning; CDIO framework; Affective Domain
Fostering Knowledge to Innovation: Enhancing Student Research Experience in Transforming Ideas into Project, Patent and Product
Authors:   Department of Mechanical Engineering, Marwadi University, Gujarat, India, Motwani K. , Chotai N. ,   Department of Mechanical Engineering, Marwadi University, Gujarat, India, Asnani M. ,   Department of Mechanical Engineering, Marwadi University, Gujarat, India, Vijriwadha S. ,   Department of Mechanical Engineering, Marwadi University, Gujarat, India
Published: April 2024

Abstract—This research study focuses on fostering a transformative journey from knowledge to innovation among students by enhancing their research experiences. The process involves converting initial conceptual ideas into tangible projects, which are subsequently developed into design patents, culminating in the creation of market-ready products. The study draws inspiration from the exploration of the critical radius of insulation, undertaken during the sixth semester of a mechanical engineering undergraduate program. This concept was practically applied to mitigate heat losses in household pressure cookers. Notably, a gap in the availability of such products in the Indian market was identified through extensive literature review, leading to the student’s engagement in this project. Encouraged by their mentors, the students presented their innovation to the university innovation, incubation, and research center, successfully obtaining financial backing. This paper comprehensively recounts the entirety of the student’s research journey. It commences with the translation of theoretical curriculum knowledge into actionable research ideas. The subsequent phases encompass various research methodologies, including theoretical analysis and simulation studies. The journey progresses with the execution of experimental approaches, effectively translating findings into design patents and, ultimately, tangible market-ready products. Overall, this research emphasizes the crucial role of research experiences in bridging the gap between theoretical learning and practical application. It underscores the significance of nurturing student’s innovative capabilities within the structured curriculum, contributing to their holistic development as future contributors to academia and industry alike. Keywords—Idea; Energy; Patent; Research; Transformation.
Cultural management as an element of strategy of development of school social capital
Authors: Juszczyk-Rygałło Joanna
Published: April 2024

Besides various proposals of solving current problem with education crisis, some new economic and social concepts appear, which are related to the notion of social capital. This article attempts to analyse conditions of social capital formation in the school as well as some factors that support its development. Particular attention is given to cultural management, which is perceived as a determinant of effective development of informal values and ethical standards common for the school community. In the conclusion it is pointed out that the supreme value of such strategic management of social capital is building relationships based on trust and partnership. This creates innovative organizational culture of school community. Its characteristic features are: a future orientation, elasticity and ability to act proactively. Thus, social capital becomes a bearer of cultural values that cause positive changes in the dominating cultural system of contemporary education. The article presents the following implications for practice or educational policy: educational policy makers can familiarise themselves with the main dimensions of the social organisation of the school, which in management theory are the basis for the growth of the social capital of the school ; Administrators can take action to develop an innovative organisational culture for the school community, adapted to current and future changes in the school environment as an organisation ; Educators can improve the individual educational environment of each pupil through cyberlearning space, which is now becoming an increasingly attractive alternative to existing methods of shaping the social capital of the school ; The participants of the educational process should together take part in the development of innovative structures of the educational community’s relational bonds through cultural management which formats the organisational culture of the school’s social capital as a system of meanings understood by the pupils and collectively accepted by them.
Parental authority of an extramarital father – choice or necessity? Selected sociological and legal aspects
Authors: Markowska-Gos Ewa
Published: April 2024

In the literature on the subject and in the media, there is increasing discussion on the intensification of cohabitation in Polish society. The situation when a child appears in a cohabiting relationship acquires special significance from a pedagogical, sociological, and psychological point of view. This article is an attempt at a multifaceted analysis of the legal status of the child in this alternative form of family life, with particular emphasis on the parental authority of the father. In this connection, the essence of the cohabiting relationship is discussed, statistical data in this regard are presented, and the growth in acceptance of this form of family life in our society and its sociodemographic determinants are pointed out. The issue of parental authority is comprehensively presented, from the perspective of sui species legal relationship, which is a normatively regulated cultural pattern of parent-child relations.
Student Academic Mobility and its Impact on Personal Development: The Experience of Finnish Universities
Authors: Zayachuk Yuliya , Dziamko Maria
Published: April 2024

The article presents an analysis of the main aspects of student academic mobility in Finnish universities and accents on its impact on the personal development of students. It is based on the theoretical analysis and systematization of literary sources, as well as empirical data of a survey of Finnish students who studies at the University of Turku and the University of Jyvaskyla. The article considers that Finland is a country of well-known achievements in education and its experience can be useful for the future of higher education in Ukraine in its current extremely difficult time. The article reveals that academic mobility of students as one of the most important among the program strategies of internationalization of higher education is an opportunity to bring new ideas, experiences and resources that can improve the quality of research and teaching, and promote innovation and cultural understanding for educational institutions, as well as to develop scientific potential, gain international experience and develop professionally for students, teachers, and researchers. It is shown that international academic mobility significantly increased over the past decade. The article discusses that Finnish universities have a developed network of partner institutions around the world, which provides students with opportunities to exchange experiences and gain new knowledge. The article presents the detailed results of an empirical study, namely a survey of Finnish students studied at the University of Turku and the University of Jyvaskyla, who have personal experience of participating in student academic mobility programs, which relate to countries where students carried out their academic mobility, advantages of student academic mobility, the impact of academic mobility on the career of students, possibility of their independent research, and other aspects firsthand.
Values Preferred by Young People Watching the American series Friends
Authors: Majkowska Małgorzata
Published: April 2024

This article is a reflection on the values that are noticed by young people watching the series „Friends”. This series was widely broadcast in the years 1994–2004. University students has been asked to watch it in any language and answer questions about its content. The respondents’ statements attempted to identify the values they prefer and assess whether they are important for their further life choices. Additionally, research investigated whether students notice that watching films in a foreign language improve their language abilities and help learn new foreign grammar structure.
Experiences of Alcoholic Families in Memories Adult Children of Alcoholics
Authors: Drzewiecka Sandra , Zalas Katarzyna
Published: April 2024

The article focuses on the analysis of the experiences of people who grew up in families affected by alcoholism. The study focuses on a group of adults, called Adult Children of Alcoholics (ADA), who experienced/are experiencing difficulties related to alcoholism of one of their parents during their childhood. The aim of the article is to present the experiences gained from the family home in the opinion of Adult Children of Alcoholics. The analysis included features and properties of the family environment, relationships with adults – parents, values valued in the family of origin, as well as an assessment of the impact of experiences acquired in childhood on functioning in adulthood.
The Use of Therapeutic Fairy Tales as a Method of Reducing Anxiety in Preschool Children
Authors: Jaworska Agnieszka
Published: April 2024

Anxieties occur at every stage of a child’s development, but in the preschool period they are most common. Children face many problems and weaknesses that they can’t cope with on their own. Therapeutic fairy tales are a great method to help them overcome them in an effective way. Thanks to their therapeutic nature, they can also be used during pedagogical therapy classes. One of the forms used to work with children struggling with various fears is fairy tale therapy. Thanks to it, children gain knowledge about their fears, learn to name their own emotions and start talking about their own problems.
Emprendimiento sostenible: un análisis bibliométrico
Authors: Blanco Dayanna , Sepúlveda Juan David , Angulo-Cuentas Gerardo
Published: April 2024

Objetivo. Analizar la información contenida en Scopus en el campo del emprendimiento sostenible e identificar la estructura del conocimiento en cuanto a temáticas relevantes y sus tendencias, autores y países líderes y su cooperación. Metodología. Paraello se aplicó un análisis bibliométrico que permitió describir y estructurar los avances, el volumen de producción y los actores más relevantes en el campo objeto de estudio; un campo en etapa de crecimiento con un interés científico por la aceleración de la transición hacia la sostenibilidad en el que predominan las investigaciones sobre negocios, administración y contabilidad. Resultados. El emprendimiento sostenible responde a los retos causados por los actuales patrones de producción y consumo al incorporar componentes ambientales, sociales y económicos en las acciones empresariales; su estudio se ha centrado principalmente en la sostenibilidad de los modelos de negocios y el análisis de los ecosistemas empresariales. Conclusiones. Las tendencias de investigación, los avances y la estructura de los involucrados permite concluir que el emprendimiento sostenible es un modelo de cambios en el sector empresarial y científico en el que se evalúa el impacto en el ambiente y en las comunidadespara modificar las condiciones existentes a través de la innovación, mejoras comerciales y tecnológicas.
Environmentally Sound Development of the Ural Industry based on the Implementation of ESG Principles
Authors:   Institute of Economics of the Ural Branch of RAS, Romanova O. A. , Ponomareva A. O. ,   Institute of Economics of the Ural Branch of RAS
Published: April 2024

The article aims to substantiate the importance of compliance with ESG principles as a factor in the environmentally sound development of industry. It is hypothesized that the indicator of the implementation of ESG principles in the industrial activity of the region is the presence of the decoupling effect on its territory. The research methodology is based on the theory of sustainable development. Methods of statistical, index, structural and comparative analysis were used. The object of study is the industrial sector of the Ural Federal Dis-trict. Official statistics and socio-economic indicators of the development of Russian regions for the period from 2005 to 2020 are analyzed. The article shows that the methodological basis for the formation of ESG principles is the optimization of the environmental and social development of economic entities with a qualitatively new corporate governance. Based on the proposed approaches to determining the decoupling effect, which is con-sidered an indicator of sustainable development, this effect was calculated for the Ural Federal District. The ob-tained results can be used to clarify the directions for improving the environmental sound development of the Ural industry.
Effects of quenching temperature on the structure, segregation, and properties of the AM4.5Kd + 0.2 wt.% La alloy after artificial aging
Authors: Slavinskaya N. A. , Ri H. , Ri E. H. , Zhivetev A. S.
Published: April 2024

The identification of structural components in the AM4.5Kd + 0.2 wt.% La alloy, subjected to quenching at different temperatures (535–605 °C) and artificial aging at 155 °C for 4 h, was conducted through electron microscopy and XRD. An increase in the quenching temperature from 535 to 605 °C promotes the enlargement of structural components, including the α-solid solution, various aluminides, and eutectics. We observed that the base metal is not homogeneous in its chemical composition, consisting of two types of solid solutions: α1 and α2. The Cu and Mn solubility in the α2-solid solution is higher than in the α1-solid solution. As the quenching temperature increases to tq = 605 °C, the copper content in the α1-solid solution decreases. In contrast, the copper content in the α2-solid solution follows a curve with two maxima at 545 °С (4.5 at.%) and 585 °С (8.7 at.%). The Mn content in the α1-solid solution decreases sharply to the 545 °С quenching temperature and remains relatively constant up to tq = 605 °С (0.2 at.%). The Mn content in the α2-solid solution follows a curve with its maximum at tq = 545 °С (4.3 at.% Mn). Subsequent temperature rise results in a sharp drop in Mn content from 1.0 at.% at t = 565 °С to 0.3 at.% at 605 °С. Hence, the max solubility of Cu and Mn in the α2-solid solution occurs at 545 °C. At 585 °С, only an elevated Cu content (~8.7 at.%) was observed. Aluminides of alloying elements with different stoichiometries crystallize at different quenching temperatures, with complex AlxTiyLazCuvCdw and AlxCuyMnzCdv alloyed aluminides being most commonly found. ncreasing the quenching temperature to 535–545 °С results in higher hardness of the AM4.5Kd + 0.2 wt.% of La alloy, reaching 98–104 HB, with subsequent decrease to 60 HB as the quenching temperature reaches 605 °С. The hardness of the unhardened alloy is 60 HB. The optimal quenching temperature for the AM4.5Kd + 0.2 wt.% of La alloy is in the range of 535–545 °С. This temperature corresponds to the highest hardness of the alloy and the microhardness of the aluminide.
Synthesis of (TiTaNb)xHfyZrzC high-entropy carbides resistant to high thermal oxidation by mechanical alloying and spark plasma sintering
Authors: Kim A. E. , Ozerskoi N. E. , Razumov N. G. , Volokitina E. V. , Popovich A. A.
Published: April 2024

This study presents the synthesis of (TiZrHfTaNb)C, (TiTaNb)0.45Hf0.275Zr0.275С and (TiTaNb)0.3Hf0.35Zr0.35С single-phase, high-entropy carbides through mechanical alloying and plasma sintering. High-entropy carbides hold promise for applications in jet engine components. We identified optimal mechanical alloying conditions to achieve powder homogeneity and minimize iron fouling. The microstructure, phase, and chemical compositions of the samples were investigated. At 1600 °C, a sample with a face-centered cubic (FCC) lattice and low content of zirconium and hafnium oxides was formed. Elevating the sintering temperature to 2000 °C facilitated oxide dissolution and the formation of single-phase, high-entropy carbides. The microhardness of the samples ranged from 1600 to 2000 HV, while the compressive strength varied between 600 and 800 MPa. Plasma heating tests demonstrated excellent resistance to thermal oxidation for (TiTaNb)0.3Hf0.35Zr0.35С, withstanding temperatures up to 2250 °C.
ASSAf Distinguished Visiting Scholar (DVS) Programme 2023/24
Authors:   Academy of Science of South Africa (ASSAf)
Published: April 2024

The Academy of Science of South Africa (ASSAf) hosted Prof Loretta Baldassar as the 2023/24 ASSAf Distinguished Visiting Scholar (DVS). The DVS Programme took place on 12 - 27 March 2024. Prof Baldassar delivered a series of lectures under the theme “Transnational Family Care: from social death to digital kinning over a century of Australian migration” at various institutions across five Provinces: the universities of the Witwatersrand (Wits), Limpopo (UL), Free State (UFS), Rhodes, Stellenbosch and University of Cape Town (UCT). She also engaged with emerging academics at these institutions as part of her research capacity development work, drawing on the tools and insights of social network analysis (SNA). Prof Baldassar is Professor of Anthropology and Sociology, Vice Chancellor’s Professorial Research Fellow, and Director of the Social Ageing (SAGE) Futures Lab at Edith Cowan University (ECU). The Academy of Science of South Africa (ASSAf) annually invites one or more distinguished scholars from abroad to present lectures at various higher education institutions around the country. The scholars are internationally prominent academics who are inspirational speakers and usually with an ability to bridge the divides between disciplines. The purpose of the Distinguished Visiting Scholars’ Programme is to fulfil one of the Academy’s strategic goals, viz. the promotion of innovation and scholarly activity. Through interaction with distinguished individual scholars from around the world, ASSAf aims to enrich and stimulate research endeavours at South African higher education and research institutions. Scholars from the humanities disciplines are invited in alternate years.
INVESTIGATION OF RESONANT PHENOMENA OF PROPELLER SHAFT LINES TORSIONAL VIBRATIONS
Authors:   Kamchatka State Technical University, Tsarenko S.N. , Romensky D.I. ,   Moscow State University of Civil Engineering, Кorzh А.S. ,   Scientific Research Geotechnological Center of the Far Eastern Branch of the Russian Academy of Sciences
Published: April 2024

The problem of torsional vibrations of propeller shaft lines is considered in the work. A two-stage rod model with distributed parameters has been adopted for the study of dynamic processes in contrast to the traditional method based on discrete masses. The active load on the engine side, as in the classical approach, is approximated by the partial sum of the Fourier series. The comparison of the calculation results according to the proposed model with the results known in the literature has been performed. It is established that both calculation methods give excessive values of forces and deformations in resonance with harmonics, for which the phase component is a multiple of the engine cycle.
Aging of alveolar type 2 cells induced by Lonp1 deficiency exacerbates pulmonary fibrosis
Authors: Zhu Weiwei , Tan Chunting , Zhang Jie
Published: April 2024

Idiopathic pulmonary fibrosis (IPF) is a progressive and chronic disease that significantly impacts patient quality of life, and its incidence is on the rise. The pathogenesis of IPF remains poorly understood. Alveolar type 2 (AT2) cells are crucial in the onset and progression of IPF, yet the specific mechanisms involved are not well defined. Lon protease 1 (LONP1), known for its critical roles in various diseases, has an unclear function in IPF. Our research investigated the impact of Lonp1 gene deletion on AT2 cell functionality and its subsequent effect on IPF development. We generated a bleomycin-induced pulmonary fibrosis mouse model with a targeted Lonp1 knockout in AT2 cells and assessed the consequences on AT2 cell function and fibrosis progression. Additionally, we constructed the MLE12 cells with stable Lonp1 knockdown and utilized transcriptome sequencing to identify pathways altered by the Lonp1 knockdown. Our results indicated that mice with AT2 cell-specific Lonp1 knockout exhibited more severe fibrosis compared to controls. These mice exhibited a reduction in AT2 and AT1 cell populations, along with an increase in p53- and p21-positive AT2 cells. Lonp1 knockdown in MLE12 cells led to the upregulation of aging-associated pathways, with fibroblast growth factor 2 (Fgf2) gene emerging as a central gene interconnecting these pathways. Therefore, loss of Lonp1 appears to promote AT2 cell aging and exacerbate bleomycin-induced pulmonary fibrosis. Fgf2 emerges as a pivotal downstream gene associated with cellular senescence. This study uncovers the role of the Lonp1 gene in pulmonary fibrosis, presenting a novel target for investigating the pathological mechanisms and potential therapeutic approaches for IPF.
ВЛИЯНИЕ УФ-ОБЛУЧЕНИЯ НА СВЯЗЫВАНИЕ БЫЧЬЕГО СЫВОРОТОЧНОГО АЛЬБУМИНА С БЕНЗИЛПЕНИЦИЛЛИНОМ
Authors:   Воронежский государственный университет, БАШАРИНА О.В. , СЕКРЕТАРЕВА У.С. , КОТОВА А.О. , ЯКУШЕНКО И.В. , АРТЮХОВ В.Г.
Published: April 2024

Целью исследования явилось изучение влияния УФ-облучения на связывание бычьего сывороточного альбумина (БСА) с бензилпенициллина натриевой солью (БП) с помощью анализа спектров поглощения белковых растворов. Исследованы спектры поглощения растворов нативного и облученного альбумина в присутствии БП. Добавление к раствору БСА антибиотика приводит к изменению конформации белка вследствие связывания с лекарственным препаратом, на это указывает повышение оптической плотности и смещение промежуточных максимумов. Предполагается, что взаимодействие БСА с БП приводит к изменению микроокружения фенилаланина, то есть данный аминокислотный остаток играет важную роль в связывании антибиотика. При взаимодействии облученного БСА с БП оптическая плотность в полосе поглощения белка увеличивается пропорционально дозе облучения, что указывает на повышение связывания УФ-облученного альбумина с лигандом.
ЭФФЕКТ СНИЖЕНИЯ ТОКСИЧНОСТИ ПРОТИВОВИРУСНОЙ СУБСТАНЦИЯ РИБАВИРИН В СРЕДАХ РАСТВОРЕНИЯ РАЗНОЙ ПРИРОДЫ
Authors:   Российский университет дружбы народов имени Патриса Лумумбы, БУРЛАКОВА А.А. , КАЗЫМОВА И.В. , УСПЕНСКАЯ Е.В.
Published: April 2024

Целью настоящей работы является оценка эффективности снижения токсичности лекарственного средства (ЛС) группы противовирусных препаратов- Рибавирин. Для этого был применён оригинальный метод биотестирования Spirotox в сочетании с модельной схемой ферментативной кинетики Михаэлиса-Ментен. Для снижения токсичности, в качестве среды растворения использовали природный комплекс гуминово-фульвовых кислот (ГК). Показано, что разведение ЛС комплексом гуминово-фульвовых кислот способствует увеличение времени жизни клеточного биосенсора по сравнению с водой очищенной Рассчитанные кинетические параметры уравнения Михаэлиса-Ментен для водных растворов Рибавирина fm=18,2 с ; Кр=2,5 · 10 моль/л и с использованием в качестве разбавителя ГК : воду очищенную (140-145 ppm) fm=1,0 с ;Кр=0,3 · 10 моль/л демонстрирует способность ГК снижать токсичность противовирусных ЛС.
ОСОБЕННОСТИ ТРАССРЕДОВОГО ПЕРЕХОДА МАКРОЭЛЕМЕНТОВ ПО ЦЕПИ «ПОЧВА-ЛЕКАРСТВЕННОЕ РАСТИТЕЛЬНОЕ СЫРЬЕ-ВОДНЫЕ ИЗВЛЕЧЕНИЯ»
Authors:   Воронежский государственный университет, ДЬЯКОВА Н.А.
Published: April 2024

Целью исследования являлось изучение транссредового перехода макроэлементов по цепочке «почва - лекарственное растительное сырье - настои и отвары». Показано, что макроэлементы составляют более 84% элементного комплекса лекарственного растительного сырья. К сильно накапливаемым макроэлементам отнесены калий и фосфор. Макроэлементам принадлежит наибольшая доля в общей сумме элементного комплекса водных извлечений (94,95-98,99%). Степень перехода калия составляла до 162,43%, фосфора - до 279,45%. Элементы, отнесенные к группе среднего захвата, также достаточно эффективно мигрировали по исследуемой цепи: доля магния, мигрирующая из почв в настои и отвары, составила до 46,36%, кальция -до 30,01%.
ПРИМЕНЕНИЕ ТОНКОСЛОЙНОЙ ХРОМАТОГРАФИИ В АНАЛИЗЕ БИОЛОГИЧЕСКИ АКТИВНЫХ ВЕЩЕСТВ ЛИСТЬЕВ ЕЖЕВИКИ СИЗОЙ (RUBUS CAESIUS L.)
Authors:   Первый Московский государственный медицинский университет имени И.М. Сеченова, ИЛЬИНА М.Б. , СЕРГУНОВА Е.В.
Published: April 2024

Целью исследования являлось изучение состава биологически активных веществ (БАВ) в листьях ежевики сизой (R.caesius L.) методом тонкослойной хроматографии (ТСХ). Сырьё было заготовлено на территории Московской области летом 2022г. Для проведения ТСХ разных групп БАВ были подобраны соответствующие условия пробоподготовки, состав подвижной фазы, пластинка, детектор. В результате исследования в листьях ежевики сизой были идентифицированы следующие соединения: аскорбиновая, лимонная, винная, янтарная кислоты, ß-аланин, L-треонин, L-глутамин, глицин, глюкоза, фруктоза, рамноза, галактоза, мальтоза, лактоза, ксилоза, раффиноза, танин, рутин, цинарозид. Полученные данные позволяют заключить, что листья ежевики сизой являются богатым источником БАВ и перспективным лекарственным растительным сырьем.
ИДЕНТИФИКАЦИЯ КВЕРЦЕТИНА И ЕГО ГЛИКОЗИДА РУТИНА В ТРАВЕ СОЛОДКИ ГОЛОЙ МЕТОДОМ ВЭЖХ
Authors:   Волгоградский государственный медицинский университет, НЕДИЛЬКО О.В. , ЯНИЦКАЯ А.В. , ГРИШАНИН Г.В.
Published: April 2024

Целью проведенного исследования являлось выделение и идентификация соединении флавоноидной природы в надземной части солодки голой методом ВЭЖХ. В работе приведены хроматограммы спиртовых извлечений, полученных из травы лекарственного растения, на которых наблюдаются пики, соответствующие стандартным образцам кверцетина и рутина. При этом отмечено доминирование последнего, что может быть использовано при разработке методики количественного определения флавоноидов в данном растительном сырье.
ИЗУЧЕНИЕ СОСТАВА ПИГМЕНТОВ В ЛИСТЬЯХ ОЛЬХИ СЕРОЙ (ALNUS INCANA MOENCH.) И ЧЕРНОЙ (ALNUS GLUTINOSA GAERTH.)
Authors:   Первый Московский государственный медицинский университет имени И.М. Сеченова, НЕСТЕРОВ Г.В.
Published: April 2024

В ГФ РФ включены соплодия ольхи, заготавливаемые от растений ольха серая (Alnus incana Moench.) и черная (Alnus glutinosa Gaerth.), используемые в качестве вяжущего средства, что обусловлено высоким содержанием в сырье дубильных веществ. Учитывая современную тенденцию изучения состава биологически активных веществ в неиспользуемых на сегодняшний день частях лекарственных растений, авторами проведен фитохимический анализ пигментов гидрофобной природы в листьях ольхи серой, черной и видовой смеси сырья. Методом тонкослойной хроматографии выявлено наличие во всех анализируемых образцах хлорофиллов и каротиноидов. Проведена количественная оценка содержания экстрактивных веществ, извлекаемых хлороформом, суммарного содержания хлорофиллов и каротиноидов и показана перспективность использования листьев ольхи фармакопейных видов для выделения растительных пигментов.
АНАТОМИЧЕСКОЕ СТРОЕНИЕ ЛИСТА ORIGANUM TYTTAHANTHUM GONTSCH
Authors:   Таджикский национальный университет, РАДЖАБЗОДА Ф.К. , ОДИНАЗОДА С.А. , ШАРИПОВА Б.Ш.
Published: April 2024

Цель данного исследования заключается в изучении структуры листа Origanum tyttahanthum Gontsch с помощью методики М.С. Гзыряна. Результаты исследования указывают на гипостоматический тип листа, а также на наличие диацитных устьиц как на верхней, так и на нижней стороне листовой пластинки. Клетки эпидермиса имеют многоугольную форму и слабоизвилистые стенки, а мезофилл состоит из клеток столбчатой и губчатой паренхимы. Встречаются простые и головчатые волоски, преимущественно на нижней стороне листа. Кроме того, в клетках листа обнаружены эфиромасличные железки и друзы оксалата кальция.
РАЗРАБОТКА И ВАЛИДАЦИЯ МЕТОДИКИ ОПРЕДЕЛЕНИЯ ПРОИЗВОДНОГО 2-АМИНОПИРРОЛКАРБОНОВОЙ КИСЛОТЫ В ПЛАЗМЕ КРОВИ
Authors:   Пермская государственная фармацевтическая академия, ЦЕЧЁЕВ А.Т. , КАРПЕНКО Ю.Н. ,   Пермская государственная фармацевтическая академия,   ООО «Парма Клиникал»
Published: April 2024

В настоящей работе представлены результаты исследований по разработке хроматографической методики определения нового биологически активного соединения с цитотоксической активностью в плазме крови. Пробоподготовка осуществлялась путем осаждения белков плазмы ацетонитрилом. Разделение проводили на колонке с обращенно-фазным сорбентом с использованием подвижной фазы на основе ацетонитрила и фосфатного буфера. В процессе валидации разработанной методики установлено соответствие ее параметров предъявляемым требованиям.
АНАЛИЗ СВОБОДНЫХ АМИНОКИСЛОТ КАШТАНА КОНСКОГО ОБЫКНОВЕННОГО ЦВЕТКОВ
Authors:   Воронежский государственный университет, ЧИСТЯКОВА А.С. , БОЛГОВ А.С. , ДУНИЛИН А.Д.
Published: April 2024

Каштана конского цветки являются перспективным видом растительного сырья. Известно, что каштана конского цветки содержат в своем составе преимущественно фенольные соединения и сапонины, данные по содержанию иных, минорных групп соединений разрозненны и не дают целостного представления о полном спектре биологически активных соединений данного вида сырья. Цель исследования - изучение качественного состава и количественного содержания суммы свободных аминокислот каштана конского цветков. Объектом исследования являлись высушенные цветки каштана конского, которые были заготовлены во время цветения в Воронежской области в 2022 году. В результате эксперимента методом ТСХ в сумме аминокислот были идентифицированы лизин, глицин, метеонин, глутаминовая кислота. Установлено количественное содержание суммы аминокислот в пересчете на глутаминовую кислоту спектрофотометрическим методом, которое составило 2,25±0,07%.
АНАЛИЗ АМИНОКИСЛОТ ЗВЕРОБОЯ ПРОДЫРЯВЛЕННОГО ТРАВЫ, ЗАГОТОВЛЕННОЙ В ВОРОНЕЖСКОЙ ОБЛАСТИ
Authors:   Воронежский государственный университет, ЧИСТЯКОВА А.С. , БОЛГОВ А.С.
Published: April 2024

Зверобоя трава давно известное и широко используемое как в официнальной, так и народной медицине лекарственное растение с огромным спектром фармакологической активности от антимикробного до антидепрессивного и др. Данные виды активности обусловлены комплексом биологически активных веществ, входящих в химический состав растения. Однако, не смотря на большое количество работ, посвященных изучению видов зверобоя, одной из мало изученных для данного растения групп веществ являются аминокислоты. Целью данного исследования являлось изучение аминокислотного состава зверобоя продырявленного травы методами ТСХ и капиллярного электрофореза. По результатам исследования аминокислотный состав зверобоя травы представлен 14 аминокислотами, наиболее богата зверобоя трава лейцином (0,051%), пролином (0,042%), гистидином и изолейцином (по 0,021%).
АНАЛИЗ АССОРТИМЕНТА МЕСТНЫХ РАНОЗАЖИВЛЯЮЩИХ СРЕДСТВ НА ПРИМЕРЕ АПТЕЧНОЙ ОРГАНИЗАЦИИ ГОРОДА ВОРОНЕЖА
Authors:   Воронежский государственный университет, АЛЕКСЕНКО Е.А. , БУЗЛАМА А.В. , ТРОФИМОВА Т.Г. , БУРЦЕВА А.С. , ПЕРОВА М.Ю.
Published: April 2024

Цель исследования - анализ ассортимента топических регенерантов и репарантов на примере аптечной организации г. Воронежа. Установлено, что более половины ранозаживляющих лекарственных препаратов производства РФ (56%), что свидетельствует об отсутствии проблемы импортозамещения. По стоимости почти половина (45%) лекарственных препаратов из группы регенерантов и репарантов входят в условно средний (100 - 300 руб. за упаковку) ценовой диапазон, что характеризует их доступность для большинства покупателей. Наибольшим спросом, согласно исследованию месячного товарооборота, пользуется оригинальный препарат Бепантен в различных ЛФ, Левомеколь в лекарственной форме мазь, Метилурацил в лекарственной форме мазь, небрендированный дженерик Декспантенол в лекарственных формах крем, мазь. Ассортимент регенерантов и репарантов в исследуемой аптечной организации составляет лишь 18% от общего количества препаратов данной группы, зарегистрированных на территории России, что может ограничить возможности выбора для покупателей.
Eficacia de los porteros de balonmano en los últimos mundiales absolutos masculino y femenino
Authors: Gómez López Manuel , Angosto Sánchez Salvador , López-Triviño Julia , Antúnez Antonio
Published: April 2024

The performance of goalkeepers can predict the final ranking of teams in tournaments. The purpose of the study was to examine the percentages of saves by goalkeepers from 15 national teams, according to the position in the field from which the shot was taken and according to the location of the shot in the goal, and to analyze the differences according to the goalkeeper's gender. A documentary study was carried out based on the data collected by the International Handball Federation of 227 games of 30 national teams that participated in the last absolute world championships of both men's (Germany-Denmark 2019) and women's (Germany 2017) handball. The results showed that the highest percentage of both men's and women's saves was obtained from shots taken from 9 meters and to the central and middle zone of the goal, and the lowest was obtained from throws in counterattack and to the lower and lateral zones of the goal. Finally, the women obtained the highest percentage of stops both before the throws from the different locations in the field and in the different areas of the goal.
Responsabilidad personal y social y práctica de actividad física en estudiantes
Authors: Sánchez-Alcaraz Martínez Bernardino Javier , Ros García Estefania , Alfonso-Asencio Manuel , Hellín-Martínez Marta , Gómez-Mármol Alberto
Published: April 2024

The aim of this paper was to analyse the levels of personal and social responsibility and physical activity participation according to students’ gender and Education Stage, and to know the relationship between these two variables. The sample consisted on 344 students (152 boys y 192 girls), between 11 and 17 years old (M = 14.03; SD= 2.15), corresponding to Primary Education Stage (N = 174) and Secondary Education Stage (N = 170), who were administered the Personal and Social Responsibility Questionnaire and the Physician-based Assessment and Counseling for Exercise. The results showed significantly higher values of personal responsibility and physical activity in boys. Thus, primary stage students showed significant higher values on personal responsibility, helping others, and physical activity than secondary stage students. Finally, the practice of physical activity was positively and significantly associated with the personal and social responsibility of the students. These data can help teachers and coaches to promote values through physical activity.
Efecto de un programa de entrenamiento táctico en fútbol juvenil: caso único
Authors: Valencia Sánchez Wilder Geovanny
Published: April 2024

The objective is to determine the effect of a training program using an active method in youth football. The study had a unique case design with pretest and post-test measurements. The participants were 18 soccer players under 15 from a club in the city of Medellin (14,94±0,4 years; 166,33±0,05 cm; 54,09±5,96 kg; 19,52±1,56 Kg/m2; 0,98±1,15 years of experience). The intervention was carried out during 20 training units in 10 weeks, which had as learning contents the offensive tactical principles of evolution. The evaluations were following up of friendly football matches with a control group that had characteristics similar to the experimental group. The games were recorded and analyzed using a previously validated observation protocol. The analysis unit was made up of 605 ball recoveries and 301 offensive sequences in total. Pearson's chi-squared test (x2) was applied for the analysis of pre-post test differences. The results indicate a statistically significant increase in offensive performance (p = 0, 04) among the number of post-test offensive sequences compared to the pretest of the experimental group. It is recommended to use a training program based on the tactical component using the active method to increase offensive performance.
O processo defensivo do handebol: uma revisão sistemática
Authors: De Oliveira Granero Gustavo , Peron Faula de Oliveira Arthur , Da Silva Musa Vinicius , Pombo Menezes Rafael
Published: April 2024

El objetivo de este estudio fue identificar el panorama de artículos originales sobre la fase defensiva del balonmano entre los años de 2000 y 2019, por medio de una revisión sistemática. La búsqueda de los artículos se realizó en siete bases de datos indexadas de revistas científicas a partir de criterios preestablecidos. Al final de la fase de selección, 33 artículos atendieron a todos los criterios de inclusión y revelaron posibles fronteras del conocimiento sobre la temática. Los resultados apuntaron que el interés por la temática es reciente, con la predominancia de estudios provenientes de universidades españolas, siendo la mayoría de estos publicados en español, seguido de la lengua inglesa. En general, hay un predominio de investigaciones con delineamiento cuantitativo en detrimento de ensayos, investigaciones cualitativas o que se utilizaron de métodos mixtos. Los contextos abordados en los estudios investigados muestran la preferencia por el análisis de equipos de alto rendimiento en competiciones como Campeonatos Mundiales y Juegos Olímpicos, en especial del sexo masculino y de la categoría adulta.
Efectos de un protocolo de entrenamiento de fuerza con autocargas y pliometría sobre el rendimiento físico en balonmano: categoría de Primera Nacional Femenina
Authors: Soto García Diego , Díaz Cruz Jorge , Bautista Iker Javier , Martínez Martín Isidoro
Published: April 2024

The aim of this research was to analyze the effects on jumping and throwing after applying a protocol of self-loading and plyometry to a women's university handball team. Eleven amateur handball players participated in the event (Mage = 23.70; SD = 2.26), who performed the training protocol for eight weeks. An experimental design was established in which pre- and post-intervention evaluations were made in which the medicine ball throw, the speed of throwing to goal and the speed of the goal were evaluated, CMJ one leg and both legs, horizontal jump and asymmetries between both legs. For the evaluation of the training effect, a dependent samples t-test was tasked. The results show that they improved in the jumping tests but not in the throwing tests. In conclusion, a protocol of self-loading and plyometrics is effective in the vertical jump.
Estado de peso, calidad de la dieta y su relación con el autoconcepto en escolares de Primaria
Authors: Carrillo-López Pedro J. , Pérez-Soto Juan José
Published: April 2024

The aim of this article was to analyse the relationship between weight status and diet quality with self-concept in primary school children. For this purpose, a cross-sectional descriptive empirical study was carried out on a sample of 246 schoolchildren (10-12 years old). Two questionnaires were used: the Piers-Harris self-concept scale and the KIDMED questionnaire. Nutritional status was assessed using the Body Mass Index (kg/m2) adjusted for sex and age. Linear regression test showed an association between higher self-concept scores and higher diet quality adjusted and, unadjusted for sex, age or overweight. In conclusion, higher self-concept in primary school children seems to be related to higher diet quality.