bluuebunny/crossref_metadata_2025 huggingface dataset:
A diversity-sensitive long-term care for gay and lesbian elders in need of care – Results of the research project GLESA
Authors: Lottmann Ralf , Kollak Ingrid
Published: May 2018

This paper presents results of the research project „Gleichgeschlechtliche Lebensweisen und Selbstbestimmung im Alter“ (GLESA) by the Alice Salomon University of Applied Sciences, Berlin, and the Berlin School of Economics and Law concerning the needs of gay and lesbian elders regarding long-term care. The main focus is on the expectations and perceptions of long-term care (facilities) of the interviewees living in a gay housing project in Berlin, Germany. The study is based on 26 interviews: with eleven gay, one lesbian and three heterosexual tenants – two of them lived in a shared community with long-term care services. Another eleven interviews were conducted with experts (five cis-female, four cis-male and two transgender) working in social and health services (social workers, carers and psychologists). The data was gathered via problem-centered interviews (Witzel 2000) and analysed with Mayrings‘ (2007) qualitative content analysis. Long-term care aspects were one out of five dimensions of the analysis. The study illustrates the discomfort of LGB elders regarding regular care services. The interviewees prefer LGB(T*I)-friendly facilities, in part because they demonstrate overt signs of diversity and promise a high competence of LGB(T*I) personnel in terms of self-determination, awareness, visibility and knowledge about LGBT*I communities. Finally, the authors advocate enhancing the concept of culture-sensitive long-term care according to diversity-sensitive aspects. A better understanding of diversity will help to better consider individuality and biographies in long-term care (facilities) and to support the social inclusion of LGB(T*I) elders in need of care.
On a Non-linear Boundary-Layer Problem for the Fractional Blasius-Type Equation
Authors: Tapdigoglu Ramiz , Torebek Berikbol T.
Published: May 2018

In this paper, we consider a non-linear sequential differential equation with Caputo fractional derivative of Blasius type and we reduce the problem to the equivalent non-linear integral equation. We prove the complete continuity of the non-linear integral operator. The theorem on the existence of a solution of the problem for the Blasius equation of fractional order is also proved.
Ulam’s-Type Stability of First-Order Impulsive Differential Equations with Variable Delay in Quasi–Banach Spaces
Authors: Wang JinRong , Zada Akbar , Ali Wajid
Published: May 2018

In this paper, Ulam’s-type stabilities are studied for a class of first-order impulsive differential equations with bounded variable delays on compact interval with finite number of impulses. Results of stability are proved via newly established integral inequality of Bellman–Grönwall–Bihari type with delay for discontinuous functions. Using this inequality for the first time and assumption of

α

$\alpha$

-H

o
¨

$\ddot{o}$

lder’s condition instead of common Lipschitz condition is novelty of this paper. Moreover, solution is obtained in quasi–Banach spaces which is best suited for obtaining results under the assumptions of

α

$\alpha$

-H

o
¨

$\ddot{o}$

lder’s condition.
AC/DC current ratio in a current superimposition variable flux reluctance machine
Authors: Kohara Akira , Hirata Katsuhiro , Niguchi Noboru , Takahara Kazuaki
Published: May 2018

We have proposed a current superimposition variable flux reluctance machine for traction motors. The torque-speed characteristics of this machine can be controlled by increasing or decreasing the DC current. In this paper, we discuss an AC/DC current ratio in the current superimposition variable flux reluctance machine. The structure and control method are described, and the characteristics are computed using FEA in several AC/DC ratios.
3-D Electromagnetic field analysis of wireless power transfer system using K computer
Authors: Kawase Yoshihiro , Yamaguchi Tadashi , Murashita Masaya , Tsukada Shota , Ota Tomohiro , Yamamoto Takeshi
Published: May 2018

We analyze the electromagnetic field of a wireless power transfer system using the 3-D parallel finite element method on K computer, which is a super computer in Japan. It is clarified that the electromagnetic field of the wireless power transfer system can be analyzed in a practical time using the parallel computation on K computer, moreover, the accuracy of the loss calculation becomes better as the mesh division of the shield becomes fine.
The CUT’s Experience during the Workers' Party Governments in Brazil (2003-2016)
Authors: Krein José Dari , Dias Hugo
Published: May 2018

This paper looks at the development of the Unified Workers’ Central of Brazil (CUT) during the four consecutive Workers’ Party (PT) governments, first under Luiz Inácio Lula da Silva and later under Dilma Rousseff. The analysis draws on various aspects of the power resources approach, but focuses specifically on institutional power. The government found it politically difficult to implement a left-wing programme, due to the complex nature of the ruling coalition and its conservative opposition in the broader context of neo-liberal hegemony and financial globalisation. By continuing to establish dialogue with social movements, the PT governments stimulated forms of social participation in developing public policies, reinforcing existing institutions and creating new ones. By using its institutional power, the CUT was able to strengthen its participation in public institutions. There were hardly any substantial debates on labour or employment conducted without the CUT’s participation. On the other hand, the privileged spaces in the labour arena did not achieve structural changes capable of redefining the country’s development model and the standard of work regulation.
The Applicability of a High-Intensity Functional Exercise Program Among Older People With Dementia Living in Nursing Homes
Authors: Sondell Anna , Rosendahl Erik , Gustafson Yngve , Lindelöf Nina , Littbrand Håkan
Published: May 2018

Background and Purpose:

Exercise programs for people with dementia need to be optimized. We therefore evaluated the applicability of a high-intensity functional exercise program among people with dementia in nursing homes with regard to attendance, achieved exercise intensity, adverse events, a focus on dementia type, and whether symptoms of dementia or other medical conditions common in this population were associated with program applicability.

Methods:

The Umeå Dementia and Exercise study, a cluster-randomized controlled trial set in 16 nursing homes in Umeå, Sweden. Ninety-three people with dementia (mean [SD] Mini-Mental State Examination score of 15.4 [3.4]) were randomized to the exercise intervention. Thirty-four participants had Alzheimer's disease (AD) and 59 non-Alzheimer's dementia (non-AD). High-Intensity Functional Exercise (HIFE) program was conducted in groups of 3 to 8 participants. Two physiotherapists led 5 sessions (45 minutes each) per fortnight for 4 months (total 40 sessions).

Results:

Median attendance rate was 82.5%. Lower limb strength exercises were performed at high or medium intensity at a median interquartile range of 94.7% (77.8%-100%) of attended sessions. Participants with non-AD performed more sessions with high intensity in strength exercises than participants with AD (median interquartile range, 53.8% [25.7%-80%] vs 34.9% [2.02%-62.9%]; P = .035). Balance exercises were performed at high intensity at a median interquartile range of 75% (33.3%-88.6%). Adverse events (all minor and temporary, mostly musculoskeletal) occurred during the exercise sessions in 16% of attended sessions. Low motivation was the most common barrier for attendance. Buildup period, low motivation, and pain were common barriers for achieving high intensity in balance and strength exercises, and fear was a barrier in balance exercises. Of medical conditions, only behavioral and psychological symptoms of dementia, including apathy, were negatively associated with applicability.

Conclusion:

A group-based, supervised, and individualized high-intensity functional exercise program seems to be applicable with regard to attendance, achieved intensity, and adverse events during the exercise sessions, in people with mild to moderate dementia in nursing homes. Effective strategies to enhance motivation to participate in exercise, as well as prevention and treatment of pain and behavioral and psychological symptoms of dementia, are important when promoting exercise participation in this population.
Eight-Week Battle Rope Training Improves Multiple Physical Fitness Dimensions and Shooting Accuracy in Collegiate Basketball Players
Authors: Chen Wei-Han , Wu Huey-June , Lo Shin-Liang , Chen Hui , Yang Wen-Wen , Huang Chen-Fu , Liu Chiang
Published: May 2018

Chen, WH, Wu, HJ, Lo, SL, Chen, H, Yang, WW, Huang, CF, and Liu, C. Eight-week battle rope training improves multiple physical fitness dimensions and shooting accuracy in collegiate basketball players. J Strength Cond Res 32(10): 2715–2724, 2018—Basketball players must possess optimally developed physical fitness in multiple dimensions and shooting accuracy. This study investigated whether battle rope (BR) training enhances multiple physical fitness dimensions, including aerobic capacity (AC), upper-body anaerobic power (AnP), upper-body and lower-body power, agility, and core muscle endurance, and shooting accuracy in basketball players and compared its effects with those of regular training (shuttle run [SR]). Thirty male collegiate basketball players were randomly assigned to the BR or SR groups (n = 15 per group). Both groups received 8-week interval training for 3 sessions per week; the protocol consisted of the same number of sets, exercise time, and rest interval time. The BR group exhibited significant improvements in AC (Progressive Aerobic Cardiovascular Endurance Run laps: 17.6%), upper-body AnP (mean power: 7.3%), upper-body power (basketball chest pass speed: 4.8%), lower-body power (jump height: 2.6%), core muscle endurance (flexion: 37.0%, extension: 22.8%, and right side bridge: 23.0%), and shooting accuracy (free throw: 14.0% and dynamic shooting: 36.2%). However, the SR group exhibited improvements in only AC (12.0%) and upper-body power (3.8%) (p < 0.05). The BR group demonstrated larger pre–post improvements in upper-body AnP (fatigue index) and dynamic shooting accuracy than the SR group did (p < 0.05). The BR group showed higher post-training performance in upper-body AnP (mean power and fatigue index) than the SR group did (p < 0.05). Thus, BR training effectively improves multiple physical fitness dimensions and shooting accuracy in collegiate basketball players.
Influence of Maximal Strength on In-Water and Dry-Land Performance in Young Water Polo Players
Authors: Keiner Michael , Rähse Holger , Wirth Klaus , Hartmann Hagen , Fries Katharina , Haff G. Gregory
Published: May 2018

Keiner, M, Rähse, H, Wirth, K, Hartmann, H, Fries, K, and Haff, GG. Influence of maximal strength on in-water and dry-land performance in young water polo players.J Strength Cond Res34(7): 1999–2005, 2020—Water polo is a multifaceted sport that is characterized by explosive actions, including sprint swimming, jumping, throwing, and struggling against opponents. Based on these factors, maximal and speed strength may be important characteristics to develop in-water polo players. However, more research is needed to further understand the relationship between various strength characteristics and water polo performance. Therefore, the primary purpose of this study was to examine the relationships between strength, speed strength, and markers of water polo performance in youth water polo players. Sixty-one male youth water polo players (10–14 years, 11.9 ± 1.3 years) had their 1-repetition maximum (1RM) bench press and squat, dry-land speed-strength performance (squat jump [SJ], countermovement jump [CMJ], and medicine ball throw), in-water performance (sprint swim and water jump), and anthropometric measurements assessed. Fifty to 60% of the variance in sprint performance was explained by the 1RM bench press and arm span. The influence of the bench press 1RM was more than twice that of the anthropometric factors. Maximum strength in the squat and speed-strength (jump height in SJ, CMJ) variables explained 18–25% variance in the eggbeater kick (a leg strike technique to stay above and jump out of water), and the bench press 1RM explained the 42% of the variance in loaded throws without the influence of anthropometric factors. This study suggests that upper- and lower-body maximal strength parameters are important predictors of the performance capacity of water polo players.
Normative Reference Values for Handgrip Strength in Chilean Children at 8–12 Years Old Using the Empirical Distribution and the Lambda, Mu, and Sigma Statistical Methods
Authors: Garcia-Hermoso Antonio , Cofre-Bolados Cristian , Andrade-Schnettler Rodrigo , Ceballos-Ceballos Rodrigo , Fernández-Vergara Omar , Vegas-Heredia Eddie D. , Ramírez-Vélez Robinson , Izquierdo Mikel
Published: May 2018

Garcia-Hermoso, A, Cofre-Bolados, C, Andrade-Schnettler, R, Ceballos-Ceballos, R, Fernández-Vergara, O, Vegas-Heredia, ED, Ramírez-Vélez, R, and Izquierdo, M. Normative reference values for handgrip strength in Chilean children at 8–12 years old using the empirical distribution and the lambda, mu, and sigma statistical methods. J Strength Cond Res 35(1): 260–266, 2021—The aim of this study was 2-fold (a) to provide sex- and age-specific handgrip reference standards for Chilean children aged 8–12 years and (b) to compare the levels of handgrip strength of Chilean children with those of children from other countries. This cross-sectional study enrolled 2,026 schoolchildren (boys n = 1,334 and girls n = 692, mean age 10.18 [1.16] years old). Handgrip strength was measured using a hand dynamometer with an adjustable grip. Relative handgrip strength was calculated by dividing handgrip strength by body mass (handgrip strength kg per mass kg). Smoothed centile curves and tables for the 10th, 20th, 30th, 40th, 50th, 60th, 70th, 80th, and 90th centiles were calculated using Cole's lambda, mu, and sigma method. The results indicate that mean handgrip strength was greater among boys than girls. Handgrip strength peaked at 16.25 (5.03) kg in boys and 14.90 (4.32) kg in girls. In addition, relative handgrip strength peaked at 0.38 (0.08) in boys and 0.34 (0.07) in girls. Chilean children of both sexes scored higher than their South American counterparts from Colombia and Peru but showed lower handgrip strength than European and Australian children. Our results provide, for the first time, sex- and age-specific handgrip reference standards for Chilean children aged 8–12.9 years. These normative reference values could help identify the levels of handgrip strength that need attention to provide appropriate feedback and advice to children about how to best improve their overall physical fitness.
Restrictive Breathing Mask Reduces Repetitions to Failure During a Session of Lower-Body Resistance Exercise
Authors: Andre Thomas L. , Gann Joshua J. , Hwang Paul S. , Ziperman Emily , Magnussen Marshall J. , Willoughby Darryn S.
Published: May 2018

Andre, TL, Gann, JJ, Hwang, PS, Ziperman, E, Magnussen, MJ, and Willoughby, DS. Restrictive breathing mask reduces repetitions to failure during a session of lower-body resistance exercise. J Strength Cond Res 32(8): 2103–2108, 2018—The purpose of this study was to determine the effect of restrictive breathing mask (RBM) on muscle performance, hemodynamic, and perceived stress variables during a session of lower-body resistance exercise. In a crossover design, 10 participants performed 2 separate testing sessions, RBM and no mask, consisting of squat, leg press, and leg extension. The paired-samples t-test was used for session rating of perceived exertion (S-RPE), perceived stress before and after, heart rate (HR), pulse oximetry, and a 2 × 4 (session [mask, no mask] × time [squat exercise, leg press exercise, leg extension exercise, total resistance exercise session]) factorial analysis of variance with repeated measures (p ≤ 0.05). A significant decrease was found in total repetitions during the RBM condition (p < 0.01). A majority of the decrease in repetitions to failure occurred in the squat (p < 0.05) and in the leg press (p < 0.01), whereas no difference was observed in leg extension (p = 0.214). A significant increase was observed in S-RPE during the RBM session (p < 0.01). A significant increase was found in prestress (p < 0.01) and poststress (p = 0.01) in the RBM session. No significant difference existed for HR between exercise sessions (p = 0.08). A significant decrease existed in pulse oximetry during the RBM session (p < 0.01). The use of an RBM had a negative effect on the number of repetitions completed during an acute session of lower-body resistance training.
Crack Size and Shape Considerations Related to Near-Threshold Fatigue Crack Growth Rate Behavior
Authors: Donald J. Keith , James Mark A. , Pettit Richard G.
Published: May 2018

It is well recognized that crack size or load history or both have an important influence on near-threshold fatigue crack rate behavior at a low stress ratio. This investigation will compare the behavior of a radial crack, such as a surface flaw or a corner crack, to that of a linear crack to see if crack shape plays a role in physically small crack to long crack behavior. Recent research has unveiled a methodology to experimentally partition plasticity from roughness- and oxide-induced crack closure, showing that nonplasticity-induced closure mechanisms have a greater influence at low Kmax by orders of magnitude. Knowledge of this is key to understanding differences between long crack and physically small crack behavior in the near-threshold regime. In this study, the well behaved 2024-T351 aluminum alloy was used to generate threshold data using numerous specimen geometries, flaw geometries, crack sizes, and test procedures to highlight not only the significance of crack size but also the role of crack shape. It will be shown both experimentally and analytically that a radial crack (surface flaw, corner crack) has significantly less remote closure and, therefore, a lower threshold than a through crack (compact tension, middle crack tension), even if the crack size is the same.
Determining the Water Holding Capacity of Synthetic Track Materials for Thoroughbred Horse Racing
Authors: Bridge J. W. , Rubin H. , Dempsey K. M. , Peterson M. L.
Published: May 2018

Wax-coated sand, fiber, and rubber surfaces have been in use for more than a decade at a number of North American Thoroughbred racetracks. These synthetic, all-weather racing surfaces were designed to allow races on wet surfaces without impacting performance. As these tracks have aged, some have areas that no longer drain properly. A number of approaches have been taken to refresh the surfaces including re-waxing, adding fiber, and even turning over the surfaces. The results have shown mixed success, with water pooling on top of some tracks and more water retained in the depth profile on other tracks. A gravity-based water holding capacity (WHC) test has been developed to determine the amount of water retained in these surfaces. Traditional permeability measurements are also used in this study. Samples of new and six-year-old synthetic surfaces are taken from four North American Thoroughbred racetracks to examine both the drainage and water holding of the material. These surfaces were identified as having both adequate and inadequate track performances during wet weather. Control samples were also prepared with and without the wax binder. Measuring the WHC at different surface locations may help racetrack superintendents identify problem areas and quantify material changes over time. Test results generally showed that a certain amount of wax binder is necessary to minimize water holding in synthetic surfaces, but too much wax is detrimental. The amount and size of the polymer fiber and rubber constituents, as well as organic material and particulates present, also affects the WHC. Developing threshold values for an “acceptable” WHC for specific synthetic racetracks, as well as understanding primary factors that affect water holding, will allow researchers to set a performance standard to determine the timing and type of renovations that are needed to maintain safe and consistent synthetic track surfaces.
Effects of Aging on General and Specific Memory for Impressions
Authors: Limbert Megan J. , Coleman Jennifer A. , Gutchess Angela
Published: May 2018

Despite the number of documented declines in memory with age, memory for socioemotional information can be preserved into older adulthood. These studies assessed whether memory for character information could be preserved with age, and how the general versus specific nature of the information tested affected outcomes. We hypothesized that memory for general impressions would be preserved with age, but that memory for specific details would be impaired. In two experiments, younger and older adults learned character information about individuals characterized as positive, neutral, or negative. Participants then retrieved general impressions and specific information for each individual. The testing conditions in Experiment 2 discouraged deliberate recall. In Experiment 1, we found that younger performed better than older adults on both general and specific memory measures. Although age differences in memory for specific information persisted in Experiment 2, we found that younger and older adults remembered general impressions to a similar extent when testing conditions encouraged the use of “gut impressions” rather than deliberate retrieval from memory. We conclude that aging affects memory for specific character information, but memory for general impressions can be age-equivalent. Furthermore, there is no evidence for a positivity bias or differences in the effects of valence on memory across the age groups.
Does Exposure to Hostile Environments Predict Enhanced Emotion Detection?
Authors: Frankenhuis Willem E. , Bijlstra Gijsbert
Published: May 2018

We used a Face-in-the-Crowd task to examine whether hostile environments predict enhanced detection of anger, and whether such enhanced cognition occurs for a different negative emotion, sadness, as well. We conducted a well-powered, preregistered study in 100 college students and 100 individuals from a community sample with greater exposure to hostile environments. At the group level, the community sample was less accurate at detecting both angry and sad faces than students; and, only students discriminated anger more accurately than sadness. At the individual level, having experienced more violence did not predict enhanced anger detection accuracy. In general, participants had a lower threshold (i.e., a more liberal criterion) for detecting emotion in response to anger than sadness. And, students had a higher threshold (i.e., a more conservative criterion) for detecting emotion than the community sample in response to both anger and sadness. Overall, these findings contradict our hypothesis that exposure to hostile environments predicts enhanced danger detection. Rather, our community sample was more prone to over-perceiving emotions, consistent with previous studies showing bias in threat-exposed populations. Future work is needed to tease apart the conditions in which people exposed to social danger show enhanced accuracy or bias in their perception of emotions.
5α-dihydroprogesterone concentrations and synthesis in non-pregnant mares
Authors: Conley A J , Scholtz E L , Legacki E L , Corbin C J , Knych H K , Dujovne G D , Ball B A , Moeller B C , Stanley S D
Published: May 2018

In vivoandin vitroevidence indicates that the bioactive, 5α-reduced progesterone metabolite, 5α-dihydroprogesterone (DHP) is synthesized in the placenta, supporting equine pregnancy, but its appearance in early pregnancy argues for other sites of synthesis also. It remains unknown if DHP circulates at relevant concentrations in cyclic mares and, if so, does synthesis involve the non-pregnant uterus? Jugular blood was drawn daily from cyclic mares (n = 5). Additionally, ovariectomized mares (OVX) and geldings were administered progesterone (300 mg) intramuscularly. Blood was drawn before and after treatment. Incubations of whole equine blood and hepatic microsomes with progesterone were also investigated for evidence of DHP synthesis. Sample analysis for progesterone, DHP and other steroids employed validated liquid chromatography–tandem mass spectrometry methods. Progesterone and DHP appeared a day (d) after ovulation in cyclic mares, was increased significantly by d3, peaking from d5 to 10 and decreased from d13 to 17. DHP was 55.5 ± 3.2% of progesterone concentrations throughout the cycle and was highly correlated with it. DHP was detected immediately after progesterone administration to OVX mares and geldings, maintaining a relatively constant ratio with progesterone (47.2 ± 2.9 and 51.2 ± 2.7%, respectively). DHP was barely detectable in whole blood and hepatic microsome incubations. We conclude that DHP is a physiologically relevant progestogen in cyclic, non-pregnant mares, likely stimulating the uterus, and that it is synthesized peripherally from luteal progesterone but not in the liver or blood. The presence of DHP in pregnant perissodactyla as well as proboscidean species suggests horses may be a valuable model for reproductive endocrinology in other exotic taxa.
Características Tecnológicas de la Fibra de Vicuñas en Semicautiverio de la Multicomunal Picotani - Región Puno
Authors: Quispe Coaquira Jesús E. , Herrera Mamani Teófilo , Apaza Zúñiga Edgar , Clavetea Quisca Ludwin , Maquera Marón Zenón
Published: June 2018

El estudio tuvo como objetivo determinar la longitud de mecha y fibra, así como el diámetro de fibra descerdada de vicuñas por clase (crías, juveniles y adultos) y sexo (macho y hembra). Se realizó en el Criadero de Vicuñas en Semicautiverio de la Multicomunal Picotani, Puno, Perú, ubicado entre 4420 y 4800 msnm. Las variables respuesta se analizaron en un arreglo factorial de 2x3 conducido en un diseño completamente al azar. Los promedios de la longitud de mecha fueron 3.03 ± 0.52 y 2.97 ± 0.51 cm para machos y hembras (p>0.05) y de 3.08 ± 0.47, 3.33 ± 0.39 y 2.59 ± 0.39 cm en crías, juveniles y adultos, respectivamente (p<0.05). Las longitudes de fibra fueron de 4.13 ± 0.53 y 4.06 ± 0.55 cm en machos y hembras (p>0.05) y de 4.22 ± 0.28, 4.57 ± 0.27 y 3.50 ± 0.34 cm para crías, juveniles y adultas, respectivamente (p<0.05). Los diámetros de fibra descerdada fueron de 12.755 ± 0.580 y 12.719 ± 0.398 μm para machos y hembras (P>0.05) y de 12.359 ± 0.352, 12.856 ± 0.442 y 12.997 ± 0.447 μm en crías, juveniles y adultas, respectivamente (p<0.05). Las variables en estudio no mostraron diferencias significativas para el factor sexo, en tanto que las vicuñas juveniles registraron la mayor longitud de mecha y fibra, y a las crías le correspondió la mayor finura (p<0.05).
A New Antiplasmodial Compound from the Papuan Marine Sponge Xestospongia sp.
Authors: Murtihapsari Murtihapsari , Suruwaky Amir M , Kadarusman Kadarusman , Kurnia Dikdik , Herlina Tati , Supratman Unang
Published: May 2018

A new antiplasmodial compound, 2-(3H-diazirine-3-yl)benzaldehyde (1), has been isolated from the Papuan marine sponge Xestospongia sp. The structure elucidation of compound 1 was determined by spectroscopic evidences including UV, IR, MS, 1D and 2D-NMR analysis. Compound 1 showed moderate antiplasmodial activity against Plasmodium falciparum with IC50 value of 1.08 x 10-6 mM. DOI:http://dx.doi.org/10.15408/jkv.v4i1.6735
Desain dan Studi In Silico Senyawa Turunan Kuwanon-H sebagai Kandidat Obat Anti-HIV
Authors: Ruswanto Ruswanto , Nofianti Tifa , Mardianingrum Richa , Lestari Tresna
Published: May 2018

Kuwanon-H merupakan senyawa flavonoid dari kulit akar  murbei (Morus alba L) yang secara in vitro berpotensi sebagai anti-HIV dibanding senyawa flavonoid lainnya yang terkandung dalam kulit akar murbei seperti morusin dan morusin 4′-glucosida. Telah dilakukan penelitian desain senyawa, penambatan molekular menggunakan ArgusLab 4.0.1 dengan metode ArgusDock, penerapan aturan Lipinski’s Rule of Five menggunakan Marvin Sketch 5.2.5.1dan uji toksisitas menggunakan aplikasi Toxtree secara in silico terhadap turunan senyawa kuwanon-H. Desain enam puluh senyawa turunan kuwanon-H dilakukan dengan cara model pendekatan Topliss pada rantai samping alifatiknya. Hasil penambatan ke-60 turunan senyawa pada reseptor HIV-1 Reverse Transcriptase (1REV) menunjukkan bahwa senyawa terbaik yaitu 3-[(2Z)-3-(siklopropilmetil)but-2-en-1-il]-8-[6-({3-[(2Z)-3-(siklopropilmetil)but-2-en-1-il]-2,4-dihidroksifenil}karbonil)-5-(2,4-di-hidroksilfenil)-3-metilsiklohek-2-en-1-il]-2-(2,4-dihidroksilfenil),7-dihidroksi-4H-kromen-4-on dengan nilai energi bebas yang lebih rendah (-12.5798 kkal/mol) dibandingkan ligan asli (-11.0445 kkal/mol) dan kuwanon-H (-11.0189 kkal/mol). Senyawa terbaik ini tidak memenuhi aturan Lipinski’s Rule of Five. Hasil prediksi uji toksisitas senyawa terbaik menurut parameter Cramer Rules termasuk kategori III, yaitu diprediksi memiliki toksisitas tinggi, menurut parameter Benigni/Bossa Rulebase diprediksi senyawa yang diuji tidak bersifat karsinogenik, genotoksik, dan nongenotoksik, sedangkan menurut parameter Kroes TTC decision tree diprediksi senyawa uji berpotensi toksik.DOI:http://dx.doi.org/10.15408/jkv.v4i1.6867
Dammarane-Type Triterpenoids from The Stembark of Aglaia argentea (Meliaceae)
Authors: Hidayat Ace Tatang , Farabi Kindi , Farida Ida Nur , Haikal Kansy , Nurlelasari Nurlelasari , Huspa Desi Harneti Putri , Maharani Rani , Supratman Unang , Shiono Yoshihito
Published: May 2018

Two dammarane-type triterpenoids, 20S,24S-epoxy-3α,25-dihydroxydammarane (1) and 3α-acetyl-20S,24S-epoxy-3α,25-dihydroxydammarane (2), have been isolated from the stembark of Aglaia argentea. The chemical structure of compounds (1 and 2) were identified by spectroscopic evidences including UV, IR, 1D-NMR, 2D-NMR and MS as well as by comparing with previously reported spectral data. Those compounds were isolated from this plant for first time. Compounds (1 and 2) showed cytotoxic activity against P-388 murine leukemia cells with IC50 values of 23.96 and 8.14 mM, respectively.DOI:http://dx.doi.org/10.15408/jkv.v4i1.7065
Determination of 137Cs Elimination from Solution By Tasikmalaya Bentonite and Belitung Quartz Sand As Barrier Material Candidate on the Near Surface Disposal Facility
Authors: Setiawan Budi , Sriwahyuni Heru
Published: May 2018

Batch technique experiment was applied to measure the elimination of 137Cs from solution using bentonite from Tasikmalaya and quartz sand from Belitung.  Bentonite material was used as barrier system surrounding on a near surface disposal facility, and quartz sand as backfill material.  The distribution coefficient (Kd) of 137Cs on bentonite and quartz sand samples have been measured. Contact time, variation of Na and Cs ion concentrations in solution were applied as the experiment parameters.  The Kd values of 137Cs on the samples were 1700 and 3200 ml/g for bentonite and 17 and 37 ml/g for quartz sand samples, respectively.  The Na and Cs concentrations in solution affected the Kd values of 137Cs on samples.  Isotherm sorption result shown that the interaction of 137Cs onto solid samples was approached with Freundlich model.  The data obtained from the experiments and then could be used for radionuclides migration assessment models of disposal facility in the future.DOI:http://dx.doi.org/10.15408/jkv.v4i1.7325
Evaluasi In Vitro Kemampuan Penyerapan Glukosa oleh Ekstrak Daun Namnam (Cynometra cauliflora) pada Otot Diafragma Tikus
Authors: Sumarlin La Ode , Suprayogi Agik , Rahminiwati Min , Satyaningtijas Aryani
Published: May 2018

Diabetes Melitus (DM) adalah kelompok gangguan metabolisme yang ditandai oleh hiperglikemia akibat kerusakan pada sekresi insulin, kerja insulin atau keduanya.  Penderita Diabetes Melitus Tipe 2 (DMT2) mencapai 90-95% dari keseluruhan populasi penderita diabetes tersebut. Salah satu tanaman yang potensial sebagai alternatif obat antidiabetes adalah tanaman namnam (Cynometra cauliflora).  Pada penelitian ini kemampuan penyerapan glukosa oleh otot diafragma yang diisolasi dari tikus non diabetes Sprague Dawley oleh ekstrak metanol daun namnam (C. cauliflora) pada berbagai konsentrasi ditentukan.  Gugus fungsi senyawa dominan pada ekstrak  menggunakan FTIR (Fourier Transform Infrared). Hasilnya menunjukkan bahwa terjadinya peningkatan penyerapan glukosa oleh diafragma ketika konsentrasi ekstrak daun namnam (C. cauliflora) meningkat dan tertinggi pada konsentrasi 450 mg/mL dengan serapan 0.4254 ± 3.23 mg/mL/30 menit dengan peningkatan sebesar 373.72% dibandingkan kontrol air.  Diduga kemampuan ekstrak tanaman C. Cauliflora menyerap glukosa disebabkan keberadaan golongan flavonoid. Oleh karena itu daun tanaman namnam (C. cauliflora) memiliki potensi sebagai obat antidiabetes DMT2 melalui mekanisme peningkatan penyerapan glukosa ke dalam sel.DOI:http://dx.doi.org/10.15408/jkv.v4i1.7345
Peningkatan Kualitas Crude Glycerol dengan Proses Adsorpsi Menggunakan Sekam Padi
Authors: Aziz Isalmi , Aristya Muhammad Nizar , Hendrawati Hendrawati , Adhani Lisa
Published: May 2018

Crude glycerol merupakan produk samping pembuatan biodiesel dengan kemurnian yang rendah karena masih mengandung senyawa pengotor seperti metanol, asam lemak bebas, katalis dan air. Senyawa pengotor ini harus dihilangkan supaya kualitas gliserol meningkat dan punya nilai jual yang tinggi. Adsorpsi merupakan salah satu metoda yang dapat digunakan untuk menyerap senyawa pengotor tersebut. Pada penelitian ini digunakan sekam padi sebagai adsorben karena mengandung selulosa. Selain itu sekam padi merupakan limbah, sehingga pemanfaatannya sebagai adsorben akan dapat menekan biaya proses pemurnian crude glycerol. Penelitian ini bertujuan untuk menentukan kondisi optimum proses (waktu, suhu, konsentrasi adsorben dan ukuran adsorben), kualitas gliserol yang dihasilkan dan karaktersitik adsorben sebelum dan sesudah adsorpsi (FTIR dan SEM). Crude glycerol terlebih dahulu diasamkan menggunakan asam fosfat dan selanjutnya di ekstraksi menggunakan metanol. Crude glycerol hasil ekstraksi selanjutnya di lakukan adsorpsi menggunakan sekam padi yang sudah diaktivasi. Hasil adsorpsi disaring dan ditentukan kadar gliserolnya. Hasil penelitian menunjukkan bahwa kondisi optimum adsorpsi diperoleh pada waktu 75 menit, suhu 90 oC, konsentrasi adsorben 20% dan ukuran adsorben 180 µm. Kualitas gliserol yang dihasilkan memiliki kadar gliserol 97.290%, air 1.698%, abu 0.885%, MONG 0.132%, tidak mengandung gula.  Spektrum FTIR sebelum adsorpsi menunjukkan adanya gugus O-H, C=O, C=C dan C-O dan setelah adsorpsi terjadi penambahan gugus C-H alifatik. Morfologi adsorben sebelum adsorpsi memperlihatkan pori-pori yang terbuka dan setelah adsorpsi pori-pori tersebut tertutupi oleh senayawa pengotor.DOI:http://dx.doi.org/10.15408/jkv.v4i1.7498
Birth Cohort Studies and the Early Origins of Adult Health and Disease
Authors: Araujo Waleska R. M. , Santos Iná S. , Barros Fernando C. , Matijasevich Alicia
Published: June 2018

Prenatal and birth cohort studies, including those that start before conception, are an epidemiologic study design that best allows for the investigation of early-life origins of adult disease. This article reviews the definition and methodology of a cohort study. We also identify the worldwide locations of the most important preconception, prenatal, and birth cohorts that have been studied, as well as describe their characteristics. Finally, we examine the importance of these studies in the context of life-course epidemiology research and discuss why new studies of this type are needed. Preconception, prenatal, and birth cohorts provide insights into the mechanism of risk and protection across the life course and between generations, and have contributed significantly to what is known today regarding the developmental origins of health and disease hypothesis.
Determination of parameters of non-uniform fractured rock massif in computing experiment
Authors: Fomychov V. , Sotskov V.
Published: June 2018

The purpose of work is creation of the computing model that based on qualifiers of described elements of geomechanical system that having the nonlinear physical nature. The procedure of computing experiment conducting that based on application of net numerical methods with determination of admissible precision limit is developed for various description schemes of mechanical condition of the environment. The iterative computing experiment under control of the system of the external estimated indicators that defining structure and a format of the description of computing area of finite element method during rock massif modeling is conducted. The area of admissible values of parameters of the elements description of geomechanical system during solution of multiple parameter problem of optimization for implicitly set entry conditions is determined. Application limits in computing models of the following groups of characteristics of description elements of computing model are defined: macro -, mini- and mixed. The three-level system of the description of mechanical characteristics of geotechnical system that managing of multiple parameter network of qualifiers of the elements description of computing area is received. Parameters of calculations of contact tasks in difficult structured geomechanical models are qualitatively improved that is provided by increasing in accuracy of the description of geotechnical system elements. Accounting of nonlinear characteristics allows performing optimization of schemes of bolting systems for various mine conditions that based on a computing experiment. The presented studies were carried out on example of conditions of the «Almaznaya” mine, southern conveyor drift, coal seam l1, depth 550m. As a result, preservation of operational characteristics of extraction mine workings of Western Donbas that were drived in complicated mining-and-geological conditions is reached by the choice of optimum parameters of bolting systems that allowing to minimize production expenses. Results that based on the executed computing experiments using the considered procedure allowed to keep operational characteristics of extraction workings with economy of materials and labor costs at the level of 9 – 17%.
Protofeminismo y masonería, factores influyentes en la España Contemporánea (1868-1900)
Authors: Roma Garcia Míriam
Published: May 2018

A partir de la Revolución La Gloriosa (1868) surgieron diferentes voces críticas con la situación y la condición de la mujer tanto por parte de hombres como por parte de mujeres y se desarrollaron durante buena parte del siglo XIX y posteriores. Estas voces fueron las que impulsaron proyectos educativos dedicados a dignificar a la población femenina. Muchos de estos proyectos fueron impulsados desde sectores como la masonería. Por ello, el presente trabajo se dedica a la búsqueda entre la relación del protofeminismo y la masonería del siglo XIX. De esta manera, se estudia, brevemente, la figura de Concepción Arenal como una de las impulsoras que asentó las bases del feminismo que se desarrollaría en España durante el siglo XX a partir de la fundación de diferentes proyectos vinculados a la masonería.
Os Maçons, a Revolução e atuação sociopolítica nas décadas de 1930 e 1940 em Pernambuco
Authors: Acioly Paz Silva Augusto César
Published: May 2018

O presente artigo procura realizar uma reflexão sobre o lugar assumido pelos maçons pernambucanos, frente à Revolução de 1930 discutindo as suas estratégias enquanto, instituição, percebendo como as suas posições frente ao movimento e suas ações na fundação de lojas e bibliotecas fomentaram o debate público e demarcaram as suas posições no cenário político-intelectual das décadas de 1930-40 em Pernambuco e as suas conexões com o Brasil e o mundo.
Literatura y ámbito masónico. A propósito de la novela Pequeñeces del jesuita Luis Coloma
Authors: Serna Galindo Ricardo
Published: May 2018

Entrevista sobre su tesis doctoral: Literatura y ámbito masónico. A propósito de la novela Pequeñeces del jesuita Luis Coloma.
Las logias italianas en Turquía: entre el fortalecimiento de la comunidad italiana y el cosmopolitismo
Authors: Locci Emanuela
Published: May 2018

El Gran Oriente de Italia ha cruzado a menudo las fronteras italianas para fundar logias en otros países. En este artículo vamos a describir y analizar el alcance y el impacto de la masonería italiana en el Imperio otomano, que se convirtió después de 1923 en la República de Turquía. De gran importancia es la propensión italiana a mezclarse con la población local, para que la comunidad italiana no sea percibida como un cuerpo extraño, sino como un complemento a la sociedad de acogida.
World Conference on Fraternalism, Freemasonry & History: Research in Ritual, Secrecy and Civil Society (Bibliothèque Nationale de France, París, 2017)
Authors: Martínez García Julio
Published: May 2018

Reseña de la World Conference on Fraternalism, Freemasonry & History: Research in Ritual, Secrecy and Civil Society (Bibliothèque Nationale de France, París, 2017).
Global History and Freemasonry: 300 years of Modernity, Sociability and Imperialism
Authors: Martínez Esquivel Ricardo
Published: May 2018

En la segunda mitad del siglo XVIII, miembros de las compañías comerciales europeas organizaron las primeras logias masónicas de ultramar en las distintas ciudades portuarias insertas en el sistema global de relaciones de mercado. A partir de ese momento y a medida que se intensificaron los imperialismos, se fundaron nuevas logias, que asociaron a una importante cantidad de extranjeros europeos en su mayoría y, desde la segunda mitad del siglo XIX, de nativos. En consiguiente, este ensayo propone interpretar desde la historia global cómo los imperialismos condicionaron la inserción de las masonerías más allá de Europa, y de qué manera funcionó como una red de sociabilidad internacional.
Estudios sobre la historia del esoterismo occidental en América Latina: Enfoques, aportes, problemas y debates, editado por Juan Pablo Bubello, José Ricardo Chaves y Francisco de Mendoça Júnior
Authors: Oviedo Salazar Mauricio
Published: May 2018

Reseña del libro Estudios sobre la historia del esoterismo occidental en América Latina: Enfoques, aportes, problemas y debates. Editado por Juan Pablo Bubello, José Ricardo Chaves y Francisco de Mendoça Júnior. Buenos Aires: Editorial de la Universidad de Buenos Aires, 2017. 348 páginas. ISBN: 978-987-4019-64-6.
Construyendo al enemigo. El escrito antimasónico en la España del siglo XVIII
Authors: Del Solar Felipe Santiago
Published: May 2018

Desde mediados del siglo XVIII el espectro de la masonería rondó por el Imperio español. A pesar de que este tipo de sociabilidad no tuvo una implantación efectiva hasta la invasión napoleónica, el escrito antimasónico ingresó tempranamente en la península y, desde allí, a sus colonias Posteriormente, con el advenimiento de la revolución, el espectro de la masonería sirvió como un elemento explicativo del cambio político y como uno de los ejes del discurso reaccionario contra el liberalismo. De este modo, nuestro objetivo es analizar la circulación del escrito antimasónico en la Europa de las luces identificando la especificad de la producción hispánica y su mutación durante el periodo revolucionario. Para ello, se analizarán las obras de autores como José Torrubia y Lorenzo Hervás y Panduro, así como también, la profusa producción periodística publicada entre 1810 y 1830 en ambas riveras del Atlántico.
Uji Hayati Lima Jenis Minuman Kemasan Gelas dengan Hewan Uji Daphnia Magna dan Mencit Jantan (Mus musculus)
Authors: Surtikanti Hertien Koosbandiah , . Hernawati , Frisda Diah , Hidayah Muhamad Taufiq
Published: May 2018

Lima jenis minuman yang terpilih yaitu panther, meico, teh zeggar, degan, dan teh bukit sudah dilakukan uji hayati. Salah satu untuk pengujian kualitas minuman tersebut, yaitu uji hayati dengan menggunakan neonate Daphnia magna  (berumur <24 jam) dan mencit jantan (Mus musculus). Pengujian menggunakan D. magna, dilakukan dalam dua tahap yaitu Range Finding test (RFT) dan Range Definitive Test (RDT), sementara uji hayati mencit jantan galur Deutschland Denken Yoken (DDY) dilakukan dengan Rancangan Acak Lengkap, dua faktorial dengan 18 kelompok perlakuan. Pengambilan sampel darah mencit jantan diambil pada bagian ekor hewan dan diperiksa dengan menggunakan metode strip dan glucometer autocheck. Hasil RFT menunjukan 50% kematian neonate D. magna terdapat pada pengenceran 10-100%. Hasil analisis menunjukkan nilai LC50-24h untuk minuman Panther (P), Meico (M), Teh Bukit (B), Teh Zegar (Z) dan Degan (D). berturut-turut adalah 39,99; 51,5; 40,9; 40,93; dan 49,74%. Hasil uji hayati menggunakan mencit jantan, terjadi kenaikan berat badan yang signifikan pada saat diberi Z, D dan B. Kenaikan kadar gula darah mencit jantan signifikan pada waktu perlakuan selama dua dan tiga minggu dengan P, M, B, Z dan D. Hal ini disebabkan kadar gula minuman dapat meningkatkan kadar gula darah. Dapat disimpulkan bahwa kelima sampel minuman tersebut bersifat toksik, karena nilai LC50 kurang dari 50% (hasil uji D. magna) dan dapat meningkatkan kadar gula darah pada mencit jantan.
CARAGEENAN OLIGOSACCHARIDES : BIOLOGICAL ACTIVITY AND ITS DEVELOPMENT OPPORTUNITIES IN INDONESIA
Authors: Subaryono Subaryono
Published: June 2018

Oligosaccharides from hydrocolloids especially carrageen now get a lot of attention because of the abundant raw material availability and various biological activities so it is potentially used in various fields both in the field of food and non food. Like oligosaccharides of terrestrial materials, carageenan oligosaccharides have many biological activities such as antibacterial, antiviral, antioxidant, immunomodulatory, antiinflamatory, anticancer, and other biological activity. Oligosaccharide carrageen can be produced either physically, chemically or enzymatically. This paper reviews articles on oligosaccharide carageenan, how it is produced, biological activity and development opportunities in Indonesia.
Discovery Systems as an Alternative to Stand-Alone Databases: The Example of Primo at BI Norwegian Business School
Authors: Dabin Emmanuelle , Preminger Michael
Published: May 2018

BackgroundDiscovery systems (DS) harvest metadata from various sources into one central index. This data can be searched through thanks to an intuitive interface, which also redirects users to full-text resources in their native databases. This paper aims at evaluating whether the DS Primo can serve as an alternative to specialized databases subscribed to by BI Norwegian Business School.Research designVarious article searches were run in Primo and four databases BI subscribes to. 1200 records were exported to EndNote. The rank order and the source of the records in Primo were kept track of. Some individual records were later checked for metadata.Results Most times, the record describing an article in Primo was not harvested from the article’s native database. When the record source was this native database, subject field’s metadata was identical. Some articles appeared twice due to metadata inconsistencies across harvested resources. Almost all records included one of the subject headings searched for. Keywords were otherwise mostly found in the records’ title. Downsizing being used in various disciplines, unexpected records were retrieved.ConclusionsNot all databases are indexed in Primo Central Index, but its size and coverage make Primo a smart choice as a one-stop search engine, if one uses the available narrowing options. It can to a certain extent function as an alternative to specialized databases for other tasks than systematic reviews, such as exploratory searches, or to get a sense of the available content.
In Memoriam: Jimmie C. Holland, M.D., and James F. Holland, M.D.
Authors: Bertagnolli Monica M.
Published: May 2018

Reflections on the legacies of Drs. James and Jimmie Holland, who became the most impactful couple in oncology as one worked to save lives by developing new therapies and the other worked to ensure the quality of the lives lengthened and saved.