bluuebunny/crossref_metadata_2025 huggingface dataset:
AN OVERVIEW OF COLORECTAL CANCER: IMPLICATION OF TWO MEDICINAL PLANTS IN THEIR TREATMENT
Authors: JYOTHI BASINI  , SIREESHA RAYADURGAM  , SWETHA DAKSHINAMURTHY
Published: October 2019

Nowadays, cancer is one of the most common diseases in humans. Among all types, colorectal cancer (CRC) is one of the most serious types diagnosed in men after lung and prostate cancer while in women it occupies the second position after breast cancer worldwide. The risk factors such as obesity, sedentary lifestyle, bad nutritional habits (high in fats and proteins), smoking, and progressive aging are the cause of CRC. The acquisition of abnormal mutations leads to a consisting of many different arrangements of events during the tumor development process. Over the years, different approaches have been employed, in the treatment of cancer. These include chemotherapy, radiotherapy, surgery, and immunotherapy. Chemotherapy is routinely used for cancer treatment, but the toxicity of chemotherapeutics on healthy cells of the human body is obvious. This is the reason for discovering the new, natural origin, substances with potential cytostatic effects and less toxic side effects on the healthy cells. Medicinal plants have a special place in the management of cancer. Numerous cancer research studies have been conducted using traditional medicinal plants to discover new therapeutic agents with fewer side effects. In this review, we are describing two medicinal plants such as Actiniopteris radiata (Sw.) Link (Mayurashikha) and Terminalia pallida Brandis (Tella karaka) (endemic plant) which are available immensely in Chittoor District are used till today by the traditional herbal practitioners, tribal people is near to Talakona forest and Ayurvedic people for various diseases and also for CRC.
PRELIMINARY PHYTOCHEMICAL SCREENING AND GAS CHROMATOGRAPHY AND MASS SPECTROMETRY ANALYSIS OF CHLOROFORM EXTRACT OF GARCINIA CAMBOGIA FRUITS
Authors: PRIYADHARISINI J
Published: October 2019

Objective: Garcinia cambogia fruit commonly known as Malabar tamarind, belongs to the family Clusiaceae, is said to show varied medicinal effects including antiobesity, antiviral, antimicrobial, anti-inflammatory, and anticancer. Hence, the present study deals with the determination of phytochemical constituents present in the chloroform extract of G. cambogia fruits and determination of bioactive compounds using the gas chromatography and mass spectrometry analysis (GC-MS) technique.

Methods: The phytochemical constituents present in the chloroform extract of G. cambogia fruits were tested by qualitative analysis, and bioactive compounds were investigated using the GC-MS technique. The analysis was carried out on a JOEL GC MATERI system with a column packed with a column HP5MS (5% phenyl, methylpolysiloxane) fused capillary column (30 × 0.25 μm ID × 0.25 μm df). The compounds are separated using helium as a carrier gas at a constant flow 1 ml/min. The mass spectra of the known compounds in the fruit extract were matched with the known components stored in the National Institute of Standard and technology library.

Results: The phytochemical test revealed the presence of xanthones, flavonoids, phlobatannins, terpenoids steroids, phenolic compounds saponins, and anthraquinones. The GC-MS analysis provided peaks of 13 different bioactive compounds, namely 3,7,11,15-tetramethyl-2-hexadecenol (37.1%), pentadecanoic acid 14-methyl-, methylester (100%), hexadecanoic acid 15 methyl-, methyl ester (100%), 9,12-octadecadienoic acid methyl ester (42.6%), docosanoic acid (100%), docosanoic acid methyl ester (37.3%), phenol, 2,4,bis1,1-dimethylethyl) (100%), 9, hexadecanoic acid methyl ester (99.2%), 10-octadecenoic acid methylester (100%), 11 eicosenoic acid methyl ester (53.1%), heptadecanoic acid 9 methyl-, methyl ester (100%), eicosenoic acid methyl ester (56.9%), and 5, 12d ethanofuro oxepino[2,3,4-mn] (2,3,4-ed) anthrace2-one 9,12-dilol 6 methyl,2a 3,4,4a,5,6,7,8a‑octahydro (19%) were reported.

Conclusion: The phytochemical investigation and determination of bioactive compounds will be considered for pharmacological activities, and further isolation of individual components would however help to find new drugs.
STEROIDS IN THE TREATMENT OF CHRONIC DISEASES
Authors: SHARMA P  , IMAM S  , MEHTA DK
Published: October 2019

Since their identification, which was almost 80 years ago, steroids have played a prominent role in the treatment of many disease states such as chronic obstructive pulmonary disease, asthma, rheumatoid arthritis, and inflammatory bowel disease. Many of the clinical roles of steroids are related to their potent anti-inflammatory and immune-modulating properties. Numerous skin diseases are successfully treated with systemic steroids. Corticosteroids, though they are lifesaving drugs, produce adverse reactions which may be mild or life threatening. Steroids have diverse effects on various systems of the body. Therefore, educational interventions among physician, patients, as well as students should be carried out to further enhance rational drug use. The purpose of this review was to identify the most commonly prescribed steroids and their side effects, basic pharmacology, complications, as well as the assessment of patient knowledge about the use of steroids in tertiary care teaching hospitals.
EFFECT OF EMBLICA OFFICINALIS FRUIT DRY POWER ON BEHAVIOR CHANGES AND ANTIOXIDANT LEVELS: AN IN VITRO AND IN VIVO STUDY
Authors: UMAMAHESWARI A  , BHUVANESWARI K  , MUTHURAMAN PL
Published: October 2019

Objective: This study aim was to compare the in vitro antioxidant property of fresh juice and dry powder of Emblica officinalis (EO) by chemical testing and 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) assay and also to observe the in vivo effect of EO fruit dry powder on food intake, body weight, behavior changes, and antioxidant levels in restraint stress rat model.

Methods: In vitro study, EO fresh juice 1% v/v and its dry powder form were analyzed for chemical testing and DPPH assay initially. In the in vivo study, 12 adult male Wistar rats were obtained. Initially, baseline parameters (Body wt, food intake, behavior changes, blood levels of superoxide dismutase, and malondialdehyde) and control values were assessed. Later 12 animals were divided into two treatment groups (1 and 2) and pre-treatment was given with dry powder of EO at a dose of 250 mg/kg and 500 mg/kg orally once a day, respectively. Animals from both the groups were restrained for 2 h/day and the same parameters were analyzed at the end of 24 h and 7 days of stress induction.

Results: In vitro study, fresh juice and dry powder preparations of EO were found to be positive for all the four chemical testing. In DPPH assay, dry powder showed better antioxidant activity (97%) than the fresh juice form (57%). In vivo study, significant antioxidant activity was seen at the dose of 500 mg/kg after day 1 and 7 days of stress induction.

Conclusion: Dry powder of EO has brought out the reversal of restraint stress-induced behavioral changes and reduced food intake, body weight, and antioxidant levels.
HELICHRYSUM LONGIFOLIUM AND HELICHRYSUM PEDUNCULATUM: A COMPARATIVE ANALYSIS OF THEIR MEDICINAL USES, CHEMISTRY AND BIOLOGICAL ACTIVITIES
Authors: ALFRED MAROYI
Published: October 2019

Helichrysum longifolium and Helichrysum pedunculatum have a long history of medicinal use, particularly managing wounds acquired during male circumcision rites in South Africa. There is a need to evaluate the existence of any correlation between the ethnomedicinal applications, the phytochemistry and pharmacological properties of the species. Therefore, in this review, analyses of the botanical, medicinal, and chemical and biological activities of H. longifolium and H. pedunculatum are presented as well as exploring the potential of the two species as important sources of health and pharmaceutical products. Information on the botany, medicinal uses, and phytochemistry and biological activities of H. longifolium and H. pedunculatum was assembled from several internet sources which included Scopus, Google Scholar, Elsevier, Science Direct, Web of Science, PubMed, SciFinder, and BMC. Additional information was sourced from journal articles, scientific reports, theses, books, and book chapters obtained from the University library. This study showed that alkaloids, flavonoids, linoleic acid, oleic acid, phenol, proanthocyanidin, saponins, and tannins have been identified from the leaves of H. longifolium and H. pedunculatum. The pharmacological research showed that H. longifolium and H. pedunculatum extracts and compounds isolated from the species have antibacterial, antifungal, anti-inflammatory, antioxidant, antiplasmodial, antiprotozoal, and cytotoxicity activities. For local communities to use H. longifolium and H. pedunculatum extracts with confidence as herbal medicines, there is a need for extensive phytochemical and pharmacological studies. Further research is required to establish the safety profiles of different H. longifolium and H. pedunculatum preparations.
TRYPANOCIDAL, ANTI-LEISHMANIAL, AND CYTOTOXIC ACTIVITY OF MUEHLENBECKIA TAMNIFOLIA (KUNTH) MEINS (POLYGONACEAE)
Authors: RODRÍGUEZ A OSCAR E  , TORRENEGRA G RUBÉN D  , POMBO O LUIS M
Published: October 2019

Objective: The objective of this study was to evaluate the activity against amastigotes of Leishmania panamensis and epimastigotes of Trypanosoma cruzi (Chagas), extracts and fractions obtained from leaves and stems of Muehlenbeckia tamnifolia.

Methods: Plant material was collected during the flowering, in the town of La Calera (Cundinamarca), at a height of 2746 m above sea level, 4°43’11”N, 3°58’12”W. Leaves and stems were extracted with light petroleum and then with ethanol. The extracts were fractionated by column chromatography on silica gel with petrol; CH2Cl2, AcOEt, and MeOH. The activity against epimastigotes and cytotoxicity was evaluated by the enzymatic micromethod with MTT. The active extracts against epimastigotes and with low cytotoxicity were also evaluated in trypomastigotes and intracellular amastigotes.

Results: The dichloromethane fraction from leaves and stems of M. tamnifolia showed the highest activity against Leishmania panamensis with an 50% of the effective concentration of 0.006 (μg/ml) and a selectivity index of 4.16. In U937 cells, six of the extracts and fractions tested showed high cytotoxicity, 50 inhibitory concentration <50 μg/ml.

Conclusions: The extracts obtained from leaves and stems of different polarities of M. tamnifolia (Kunth) Meins, revealed a moderate effect against amastigotes of L. panamensis (Leishmaniosis) (low polarity fractions) and a low effect against epimastigotes of T. cruzi (Chagas).
SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL THIAZOLE-PYRAZOLE INTEGRATED CHALCONES AS ANTIOXIDANT AND ANTI-INFLAMMATORY AGENTS
Authors: DNYANESHWAR SIRSAT  , PRADEEP KATE  , MADHUSUDAN BACHUTE
Published: October 2019

Objective: The objective of the present study was to synthesize the thiazole-pyrazole integrated chalcones and their in vitro antioxidant and anti- inflammatory evaluation.

Methods: The designed hybrid thiazole-pyrazole integrated chalcones (3a-j) were synthesized by Claisen–Schmidt reaction of substituted 1-(4-methyl-2-phenylthiazol-5-yl) ethanone and substituted pyrazole aldehyde in the presence of 10% NaOH in ethanol solvent under reflux condition. The chemical structures of synthesized compounds were confirmed by IR, 1H nuclear magnetic resonance (NMR), 13C NMR, and high- resolution mass spectra.

Results: All the title compounds were screened for their in vitro antioxidant and anti-inflammatory activity. The screening data indicated that tested compounds showed potent antioxidant activity with moderate anti-inflammatory potential.

Conclusion: Antioxidant screening data reveal that most of the synthesized compounds possess excellent 1,1-diphenyl-2-picrylhydrazyl and NO radical scavenging activity. Most of the compounds found to possess marked anti-inflammatory potential by effectively inhibiting the heat-induced albumin denaturation.
EXPERIMENTAL STUDY ON SWISS WHITE MICE TO EVALUATE THE ANTIANXIETY EFFECT OF COMMON WILD FIG EXTRACT (FICUS THONNINGII)
Authors: WADIONI ADUEMA
Published: October 2019

Objective: Since prehistoric times, man has relied on herbal plants as a source of medicine in curing various ailments. This study was carried out to assess the antianxiety-like effect of the ethanol extract of wild fig (Ficus thonningii) in Swiss white (CD-1) mice.

Methods: Thirty Swiss mice were randomly divided into three groups (1–3) (n=10). Group 1 (control) was administered normal rat fed and saline, while Group 2 (low dose) and Group 3 (high dose) were administered 10 mg/kg w/w and 20 mg/kg w/w of the plant extract, respectively. The elevated plus maze was used to assess anxiety-related behaviors.

Results: Data were analyzed using the statistical tools (one-way ANOVA and student t-test). Results revealed anxiety-like behavior in the low- and high-dose-treated mice when compared to the control.

Conclusion: Therefore, administration of F. thonningii reduced an anxiety-like behavior in mice.
The ameliorating effect of uncooked beans diet in CD-1 mice
Authors: Wadioni Aduema Nil , Awka Abgai Johnson , Chris Wariso Akunah
Published: October 2019

This study was therefore, designed to investigate the ameliorating effect of uncooked beans on pain sensation using three groups of Swiss white mice (control and test) weighing 20g-30g (n=10 each).The control group received normal rodent chow, while the test group received 15g of uncooked beans in 15g of rodent chow per day and serotonin precursor (5HTP) (0.2mg/15g w/w) diet. Water was given adlibitum while daily food and water intake, as well as body weight changes, were monitored during the 30-day study. The formalin tests were used to assess pain sensation. The results showed that in the formalin test, the frequencies and durations of paw licks and paw attention in both phases of the test was significantly lower (P< 0.05) compared to the control group. Therefore, consumption of uncooked Nigeran beans diet decreases pain sensation in mice.Â  Â  Â
AN UPDATED OVERVIEW OF POLYCYSTIC OVARY SYNDROME
Authors: Kanchan Choudhary  , Ranjan Singh  , Ajay Garg  , Nitesh Verma  , Anjali Purohit  , Deepika Deora
Published: October 2019

Polycystic ovary syndrome (PCOS), also known as Stein-Leventhal Syndrome, was first described in 1935. PCOS, which may also be referred to as polycystic ovary disease is the most common hormonal disorder found in premenopausal women. PCOS is the most common endocrine disorder in women of reproductive age and is the most common cause of infertility due to ovulation. A PCOS is an endocrine disorder which affects the adolescent girls. A PCOS is a condition in which a woman has an imbalance of female sex hormones. This may lead to changes in the menstrual cycle, cyst in the ovary, failure to conceive, and other health problems. It is a common health problem among teenagers and young women. It affects 5–10% of women in their reproductive years. These problems cause infertility. Two principal components to diagnose this syndrome are menstrual dysfunction and clinical or laboratory hyperandrogenism in which these items are used in clinical diagnosis. PCOS is a hormonal disorder that affects between 5% and 10% of women of reproductive age and remains the most enigmatic reproductive disorders. The most common symptoms of PCOS are obesity, acne, amenorrhea, irregular menstrual cycles, hirsutism, insulin resistance (IR), and high cholesterol. Due to the varied nature of PCOS and the large range of possible signs and symptoms, health personnel need a thorough knowledge of the disorder and its management. It is a major disorder characterized by elevated levels of male hormones (androgens), acne, and hirsutism. It can even cause IR, anovulation, and infertility on prolonging incidence of cysts. One of the treatments for PCOS is the use of synthetic medicine, which can help to treat PCOS but with side effects. However, many women who suffer from PCOS opt to use alternative medicine in conjunction with traditional medicine to improve their condition. There are some herbs that are very helpful in treating PCOS. Since PCOS is a curable disorder, it can be cured by the use of natural remedies or allopathic medication. There is a growing interest in herbal remedies or allopathic medication to cure the PCOS. There is a need to change the lifestyle management, diet to control the PCOS level. The natural remedies include treatment with phytoestrogenic and non-estrogenic herbs such as Licorice, Ginseng, Black cohosh, Dong, soy, evening primrose, honey, fenugreek, Schisandra root, and many other which are effective and safe. Many plants have been highly esteemed sources and have advantages which reduce PCOS and also having a hypoglycemic effect. In this review, an attempt has been made to study the use of natural remedy for the treatment of PCOS.
Пленочные конденсаторы WIMA: электронные компоненты с безупречной репутацией
Authors: Соколов М.
Published: October 2019

Пленочные конденсаторы WIMA предназначены для применения в широком спектре приложений, в частности в силовой и автомобильной электронике, системах освещения, медицинском оборудовании, телекоммуникациях. Наряду со стандартными изделиями компания предлагает кастомизированные решения. В статье рассмотрена полная номенклатура конденсаторов, выпускаемых компанией WIMA
Как правильно подготовить проект печатной платы к производству
Authors: Баринова О.
Published: October 2019

Приведены типичные ошибки конструкции печатных плат (ПП), приводящие к проблемам при их изготовлении. Описаны основные параметры ПП, которые необходимо указать при оформлении заказа на изготовление. Рассмотрены причины возможных затруднений при конвертации проекта в САМ-систему.
A infiltração online no processo penal – Notícia sobre a experiência alemã
Authors: Greco Luís , Gleizer Orlandino
Published: October 2019

O artigo descreve a discussão alemã sobre a técnica de investigação da infiltração online no processo penal e tenta extrair lições para o sistema brasileiro.
Novas tecnologias e restrições à liberdade pessoal: a vigilância com dispositivos eletrônicos do imputado submetido a medidas cautelares
Authors: Negri Daniele
Published: October 2019

O artigo evidencia a ambiguidade das relações entre a vigilância com dispositivos eletrônicos do imputado submetido a medidas cautelares e o princípio da restrição mínima à liberdade pessoal, dissipando o frequente estereótipo em relação à idoneidade de tais dispositivos para reduzir o encarceramento. No entanto, a contínua evolução técnica dos dispositivos de vigilância corre o risco de degradar a dignidade da pessoa. Outra questão pertinente refere-se ao tratamento a que se submete o imputado no caso em que a administração pública não é capaz de garantir um número suficiente de dispositivos eletrônicos. A conclusão é no sentido de que, se não houver aparelhos disponíveis, o juiz terá que determinar a medida de prisão domiciliar, menos aflitiva em relação à prisão em um instituto penitenciário, para não violar a proibição de excesso na restrição da liberdade pessoal.
ANALYSIS OF FACTORS THAT INFLUENCES THE STUDENTS DECISION IN CHOOSING PHARMACEUTICAL DIPLOMA III PROGRAM IN BUKITTINGGI THAT IS MEDIATED BY MOTIVATION VARIABLE
Authors: Yonrizon Yonrizon
Published: October 2019

Competitive competition in the world of education services is influenced by the consequences of higher education that has the ability to compete that can survive and achieve the target set. Currently, the existing college are competing to develop their potential and ability to attract prospective students. Therefore, the college must create a Marketing Mix Services strategy that is the product, prices, location, promotion, people, process, physical evidence, and brand image mediated by motivation.The approach used is the survey, which is the activity of collecting data as much as possible about the facts that are supporters of the research, with a view to know the status, symptoms, determine the similarity of status by comparing with the standards that have been selected and or determined. (Arikunto & Kusyati, 2015). This research was conducted to determine the effect of product, price, location, promotion, people, process, physical evidence, brand image, to student's motivation in making decision to choose college of Pharmacy in Bukittinggi. The result of research shows that product, price, process, brand image, have positive and significant effect to motivation, while location, promotion, person, physical proof have no significant effect to motivation and motivation have positive and significant influence to decision of vote

 

Persaingan kompetitif dalam dunia layanan pendidikan dipengaruhi oleh konsekuensi pendidikan tinggi yang memiliki kemampuan bersaing yang dapat bertahan dan mencapai target yang ditetapkan. Saat ini, perguruan tinggi yang ada bersaing untuk mengembangkan potensi dan kemampuan mereka untuk menarik calon siswa. Oleh karena itu, perguruan tinggi harus membuat strategi Marketing Mix Services yaitu produk, harga, lokasi, promosi, orang, proses, bukti fisik, dan citra merek yang dimediasi oleh motivasi. Pendekatan yang digunakan adalah survei, yaitu kegiatan mengumpulkan data sebanyak mungkin tentang fakta-fakta yang menjadi pendukung penelitian, dengan maksud untuk mengetahui status, gejala, menentukan kesamaan status dengan membandingkan dengan standar yang dimiliki telah dipilih dan atau ditentukan. (Arikunto & Kusyati, 2015). Penelitian ini dilakukan untuk mengetahui pengaruh produk, harga, lokasi, promosi, orang, proses, bukti fisik, citra merek, terhadap motivasi siswa dalam mengambil keputusan memilih perguruan tinggi Farmasi di Bukittinggi. Hasil penelitian menunjukkan bahwa produk, harga, proses, citra merek, berpengaruh positif dan signifikan terhadap motivasi, sedangkan lokasi, promosi, orang, bukti fisik tidak berpengaruh signifikan terhadap motivasi dan motivasi berpengaruh positif dan signifikan terhadap keputusan pemilihan.
Pengaruh Kualitas Aparatur dan Skema Pengendalian Internal terhadap Antisipasi Korupsi Berjamaah dalam Pelaksanaan APBD dengan Integritas sebagai Variabel Moderating
Authors: Nasution Dito Aditia Darma
Published: October 2019

Study aims to examine the effect of the quality of the apparatus and the internal control scheme on the anticipation of corruption together in the implementation of the regional budget revenue and expenditure (APBD) with integrity as moderating. This study uses a survey method with instruments in the form of a questionnaire. The number of samples used was 136 head of advice organizations regions in 33 regencies/cities in the scope of North Sumatera Province where the whole samples carried out the APBD process each year. Data analysis using multiple linear regression and moderating regression analysis (MRA). The results showed that the quality of the apparatus and internal control schemes had a significant effect on the anticipation of corruption together in the implementation of the APBD, and integrity was was proven to moderate the influence of the quality of apparatus and schemes internal control on anticipating corruption together in the APBD implementation.

Penelitian ini bertujuan untuk menguji pengaruh kualitas aparatur dan skema pengendalian internal terhadap antisipasi korupsi berjamaah dalam pelaksanaan Anggaran Pendapatan dan Belanja Daerah (APBD) dengan integritas sebagai pemoderasi. Penelitian ini menggunakan metode survey dengan instrumen berupa kuesioner. Jumlah sampel yang digunakan adalah 136 kepala organisasi perangkat daerah di 33 Kabupaten/kota pada lingkup Provinsi Sumatera Utara yang mana keseluruhan sampel melaksanakan proses APBD setiap tahunnya. Analisis data menggunakan regresi linier berganda dan Moderated Regression Analysis (MRA). Hasil penelitian menunjukkan bahwa kualitas aparatur dan skema pengendalian internal berpengaruh signifikan terhadap antisipasi korupsi berjamaah dalam pelaksanaan APBD, serta integritas terbukti sebagai pemoderasi pengaruh kualitas aparatur dan skema pengendalian internal terhadap antisipasi korupsi berjamaah dalam pelaksanaan APBD.
PSYCHOLOGICAL CAPITAL AS A MEDIATION, RELATIONSHIP BETWEEN EMPOWERING LEADERSHIP , TRANSFORMATIONAL LEADERSHIP BEHAVIOR, PROACTIVE PERSONALITY TO INDIVIDUAL JOB PERFORMANCE
Authors: Andri Gus Andri , Adawiyah Wiwiek Rabiatul , Purnomo Ratno
Published: October 2019

This study aims at examine is the moderating role of psychological capital on the relationship, empowering leadership, transformational leadership behavior, and proactive personality toward individual job performance. The samples are 215 respondents using questionaire. The respondents are Minang migrant entrepeneurs in Purwokerto-Central Java. Data analysis using Structural Equation Model (SEM). The result of this study shows that the first hypothesis test, the influence of empowering leadership toward employee’s proactive personality. The second hypothesis test, the influence of transformational leadership behavior toward Employee’s proactive personality. The third hypothesis, the influence of employee’s proactive personality toward psychological capital. Based on Sobel Test, psychological capital mediates the relationship between employee’s proactive personality and individual performance 

Tujuan Penelitian ini dilakukan adalah untuk menguji apakah variabel modal psikologis sebagai variabel mediasi mempengaruhi hubungan antara kepemimpinan yang memberdayakan, kepemimpinan transformasional, dan kepribadian proaktif terhadap kinerja individu. Penelitian ini mengambil sampel sebanyak 215 responden dengan menggunakan kuesioner. Responden adalah pengusaha Perantau Minang di Purwokerto-Jawatengah. Fonemena gab yang terjadi kesenjangan   kepemimpinan perantau Minang yang tergabung dalam Ikatan keluarga Minang dibandingkan dengan suku lainnya dalam membangun kewirausahaan di Purwokerto-Jawatengah. Permasalaha penelitian yang ditemukan adalah terbatasnya pembahasan modal psikologi kewirausahaan, sehingga faktor yang mendorong individu secara psikologis dan proaktif dalam keberhasilann kinerja semakin rendah. Analisis data menggunakan model persamaan struktural (SEM). Hasil penelitian menunjukkan hipotesis pertama, adanya pengaruh pemberdayaan kepemimpinan terhadap kepribadian proaktif individu.  Hipotesis dua, adanya pengaruh kepemimpinan transformasional terhadap kepribadian proaktif individu. Hipotesis tiga, adanya pengaruh kepribadian proaktif individu terhadap modal psikologis. Dan pada hipotesis   empat, pengaruh modal psikologis memediasi hubungan antara kepribadian proaktif individu dengan kinerja individu, berdasarkan hasil uji sobel, maka nilai 3,62 Sobel test; p <0.0012).
BIOSORPSI SENYAWA PARASETAMOL YANG BERPOTENSI DALAM PENANGANAN LIMBAH OBAT
Authors: Wardi Epi Supri
Published: October 2019

Parasetamol merupakan obat analgetik dan antipiretik yang banyak digunakan oleh masyarakat. Jika penggunaannya banyak dimasyarakat maka produksi Parasetamol akan semakin bertambah dan semakin banyak pula limbah yang dihasilkan. Parasetamol akan memberikan efek buruk untuk lingkungan perairan, terutama organisme akuatik dan makhluk hidup disekitarnya. Pada penelitian ini digunakan jamur Saccharomyces sp. untuk mengabsorpsi senyawa Parasetamol. Proses biosorpsi dilakukan selama 6 hari menggunakan larutan Parasetamol 8 mg/L. Analisis hasil biosorpsi menggunakan alat Spektrofotometer UV-Vis dan HPLC pada panjang gelombang 257 nm. Hasil yang didapat dengan Spektrofotometri UV-Vis menunjukkan peningkatan absorban sebelum dan sesudah biosorpsi. Hasil HPLC menunjukkan adanya penurunan puncak sebelum dan sesudah biosorpsi dan munculnya puncak-puncak baru. Puncak-puncak baru tersebut merupakan senyawa intermediet dari Parasetamol. Dari pengujian menggunakan alat SEM (Scanning Electron Microscope) diperoleh permukaan jamur Saccharomyces sp. yang berbeda-beda sebelum dan sesudah biosorpsi. Dapat dikatakan bahwa jamur Saccharomyces sp. dapat membiosorpsi senyawa Parasetamol dalam proses biosorpsi
Uji Aktivitas Antioksidan Teh Daun Sirsak (Annona Muricata Linn) Berdasarkan Teknik Pengolahan
Authors: Yulia Mega , Ranova Riki
Published: October 2019

Teh merupakan salah satu minuman yang banyak dikonsumsi oleh masyarakat setelah air.   Berbagai macam jenis daun telah diolah menjadi teh oleh masyarakat seperti daun sirsak. Manfaat yang diharapkan dari mengkonsumsi teh daun sirsak adalah sebagai sumber antioksidan yang dapat menangkal berbagai jenis penyakit karena adanya kandungan acetogenin. Untuk menghasilkan teh yang bermutu tinggi, penanganan pucuk pasca panen perlu dilakukan dengan teknik sebaik mungkin. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan ekstrak teh daun sirsak berdasarkan variasi teknik pengolahan teh. Pengolahan dilakukan dengan 3 (tiga) variasi teknik pengolahan teh yaitu teh hijau, teh hitam dan teh oolong. Uji aktivitas antioksidan dilakukan dengan metoda penangkapan radikal bebas menggunakan DPPH (1,1-Difenil-2-pikrihidrazil).  Hasil penelitian menunjukan bahwa persentase inhibisi teh hijau sebesar 42,776%, teh oolong 39,962%, dan teh hitam 43,902%.  Aktivitas antioksidan tertinggi didapatkan pada pengolahan teh hitam daun sirsak.  Dari hasil penelitian dapat disimpulkan bahwa perbedaan teknik pengolahan teh tidak memberikan pengaruh terhadap aktivitas antioksidan.

Tea is one drink that is widely consumed by people after water. Various types of leaves have been processed into tea by the people such as soursop leaves. The expected benefits of consuming soursop leaf tea is as a source of antioxidants that can ward off various types of diseases due to the presence of acetogenin. To produce high quality tea, handling after harvest needs to be done with the best possible technique. This study aims to determine the antioxidant activity of soursop leaf tea extract based on variations in tea processing techniques. Processing is done with 3 (three) variations of tea processing techniques, there are green tea, black tea and oolong tea. The antioxidant activity test was carried out by the method of capturing free radicals using DPPH (1,1-Diphenyl-2-pikrihidrazil). The results showed that the percentage of inhibition of green tea was 42.777%, oolong tea was 39.962%, and black tea was 43.902%. The highest antioxidant activity was found in the processing of soursop leaf is a black tea. From the results of this study can concluded there are differences in tea processing techniques do not affect the antioxidant activity
Implementation of the Integrity Zone Development Program towards a Corruption-Free Area and a Serving Clean Bureaucracy Region
Authors: Pratama Prasetya Eka , Kamil Muhammad , Salahudin Salahudin
Published: October 2019

Government bureaucracy is an institution responsible for carrying out the functions of public services, community empowerment to the development of a country, so its presence is very crucial in supporting the state administration system. In reality, government bureaucracy has quite complicated issues, namely the widespread acts of corruption and public services that have not been maximized. Therefore, the Central Government's attempts to address current issues through Ministry of Empowerment of State Apparatus and Bureaucracy Reform to resolve existing problems are implementing an integrity zone development program, both at the central and regional levels. The program aims to create a corruption-free government bureaucracy and enhance the quality of public services. The research method used is descriptive qualitative. Methods for collecting data are through observation, interviews, and documentation. The theory used in this study is the Edwards III model's policy implementation theory, which consists of communication factors, implementing factors, human resource factors, and bureaucratic structure factors. The results of the study found that the Program had been implemented in the Malang Regional Tax Service Agency. The obstacles encountered are in the bureaucratic culture, human resources and public service systems that apply. The researchers' suggestion is that there must be further innovation and periodic supervision of agencies so that the implementation of the program has good results in implementing of bureaucratic reform, especially in Malang City.
Implementation of the Integrity Zone Development Program towards a Corruption-Free Area and a Serving Clean Bureaucracy Region
Authors: Kapti Prasetya Taruma Eka , Kamil Muhammad , Salahudin Salahudin
Published: October 2019

Government bureaucracy is an institution responsible for carrying out the functions of public services, community empowerment to the development of a country, so its presence is very crucial in supporting the state administration system. In reality, government bureaucracy has quite complicated issues, namely the widespread acts of corruption and public services that have not been maximized. Therefore, the Central Government's attempts to address current issues through Ministry of Empowerment of State Apparatus and Bureaucracy Reform to resolve existing problems are implementing an integrity zone development program, both at the central and regional levels. The program aims to create a corruption-free government bureaucracy and enhance the quality of public services. The research method used is descriptive qualitative. Methods for collecting data are through observation, interviews, and documentation. The theory used in this study is the Edwards III model's policy implementation theory, which consists of communication factors, implementing factors, human resource factors, and bureaucratic structure factors. The results of the study found that the Program had been implemented in the Malang Regional Tax Service Agency. The obstacles encountered are in the bureaucratic culture, human resources and public service systems that apply. The researchers' suggestion is that there must be further innovation and periodic supervision of agencies so that the implementation of the program has good results in implementing of bureaucratic reform, especially in Malang City.
Resource Transformation and Survival KEDA as Broker In Ekploitation Gold Mine In Botak Mountain Buru District Maluku Province
Authors: Solissa Marcelino
Published: October 2019

This research entitled "Resource Transformation and Keda Survival as Broker in Exploitation of Gold Mine in Baldy Mountain of Buru Maluku Regency". The research with the title aims to know and analyze the transformation of resources and the survival of Keda as a broker in gold mining activity in bald mountain. This research uses a qualitative research type that prioritizes case studies. Data collection techniques such as observation and interview. The elite theory and brokerage concept is used as a blade analysis in reviewing research results. Data analysis techniques are done quickly in the process of interpretation so that data that has been collected does not experience freezing or even become expired. The results of this study show that Keda transformed from the symbolic-based resources of customs and eucalyptus land to material-based resources (gold) by exploiting the illegal gold of bald mountain. In addition, Keda uses wealth as a key resource for building political networks and able to survive to respond to government policies.keywords: Transformation, Survival, Keda, Eksploitation, Gold Mine
Tracer Study terhadap Alumni Fakultas Ilmu Kesehatan UPN “Veteran” Jakarta di Rumah Sakit Wilayah Jakarta dan Depok
Authors: Wahyuningtyas Widayani , Fauziyah A’immatul , Nasrulloh Nanang
Published: October 2019

Pertumbuhan lulusan Fakultas Ilmu Kesehatan Universitas Pembangunan Nasional “Veteran” Jakartasejak tahun 2014-2016 mengalami peningkatan setiap tahunnya sekitar 9%. Tujuan penelitian untukmengetahui persepsi pengguna terhadap mutu lulusan, kinerja lulusan dan kepuasan pengguna rumah sakitterhadap alumni Fakultas Ilmu Kesehatan Universitas Pembangunan Nasional “Veteran” Jakarta. Penelitianobservasional analitik dengan pendekatan cross sectional. Populasi terjangkau penelitian ini seluruh alumniFakultas Ilmu Kesehatan Universitas Pembangunan Nasional “Veteran” Jakarta yang bekerja di RumahSakit sedangkan populasi target adalah lulusan yang bekerja di lima rumah sakit wilayah Kota Depok danDKI Jakarta. Sampel dalam penelitian ini berjumlah 80 orang yang ditentukan secara proportional randomsampling. Pengumpulan data akan dilaksanakan dengan metode kuantitatif dengan Instrumen penelitianberupa kuesioner yang dirancang dengan jawaban tertutup. Dengan menggunakan analisis diskrptif danmatriks IPA. Hasil dari uji analis didapat kualitas lulusan atribut tanggung jawab sebesar 4,73 dan kepuasanpengguna dengan atribut kepercayaan pengguna sebesar 7,70. Kepercayaan pengguna terhadap kualitas dankinerja lulusan fkes baik
Model Proyeksi Kebutuhan Bidan untuk Pelayanan Antenatal di Indonesia
Authors: Dewi Evindiyah Prita , Umniyatun Yuyun
Published: October 2019

Penyediaan pelayanan antenatal yang berkualitas dan terdistribusi dengan baikakan menurunkan kematianibu selama menjalani kehamilannya. Perencanaan kebutuhan bidansangat penting untuk memenuhikebutuhan masyarakat akan pelayanan antenatal. Penelitian ini merupakan penelitian operasionaluntukmendapatkan model matematika dari model proyeksi kebutuhan bidan untuk pelayanan antenatal 2007 –2020. Data primer yang digunakan adalah lamanya waktu pemberian pelayanan antenatal oleh bidan kepadasatu orang ibu hamil pada setiap kali kunjungannya yang diambil dengan menggunakan formulir worksampling di dua Puskesmas Kecamatan di Kabupaten Sumedang tahun 2018.Hasil penelitian menunjukanrata-rata lamanya waktu bidan untuk memberikan pelayanan antenatal adalah 26,3 menit untuk setiapkunjungan. Total waktu yang dibutuhkan oleh bidan untuk memberikan Paket Pelayanan Antenatal untuksatu orang ibu hamil adalah 147 menit. Persentase Waktu Kerja Efektif (WKE) Bidan terhadap Pelayananantenatal adalah 0,21%. Angka pertumbuhan rata-rata jumlah ibu hamil dari tahun 2017 sampai 2020adalah -0,007. Artinya jumlah ibu hamil dari tahun ke tahun terus mengalami penurunan.Pada tahun 2020,diperkirakan jumlah proyeksi ibu hamil adalah 5.218.028 jiwa.Model matematika yang didapatkan adalah0,0021 WKE x [∑ ibu hamil thn 2017 (1 + (- 0,007)n]. Kesimpulan penelitian ini jumlah suplai/produksi bidanperlu diturunkan.Pemerintah harus mengontrol jumlah bidan yang dihasilkan oleh institusi pendidikan.
Hubungan Pengetahuan Anemia, Pengetahuan Tablet Tambah Darah, Status Gizi dan Asupan Gizi (Fe) dengan Anemia Remaja Putri di SMA/K Kota Depok Tahun 2017
Authors: Simanungkalit Sintha Fransiske , P Ikha Deviyanti , Arini Firlia Ayu
Published: October 2019

Anemia gizi besi merupakan salah satu dari empat masalah utama kesehatan masyarakat. Anemia padaremaja putri khususnya dapat menurunkan prestasi belajar. Survei kesehatan rumah tangga (SKRT) tahun2005, menunjukkan bahwa prevalensi anemia pada remaja putri usia 10 – 14 tahun adalah sebesar 57,1%.Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi kejadian anemia pada remajaputri SMA/K di Depok tahun 2017. Penelitian ini merupakan observasional analitik dengan desain Crosssectional. Alat ukur penelitian ini adalah kuesioner pengetahuan, timbangan berat badan, microtoise dankuesioner Food Frequency Questionaire. Variabel yang diteliti adalah pengetahuan tentang anemia dantablet darah, status gizi berdasarkan IMT/U, asupan gizi (Fe dan protein), dan kadar Hb. Sampel yangdigunakan dalam penelitian ini sejumah 122 orang siswi yang bersekolah setingkat SMA/K di Kota Depokpada tahun 2017. Uji statistik yang digunakan adalah uji chi-square. Penelitian ini mendapatkan tidak adahubungan antara pengetahuan tentang anemia dan Tablet tambah darah dengan kejadian anemia, tidak adahubungan antara status gizi dengan kejadian anemia, dan tidak ada hubungan antara asupan Fe dan proteindengan kejadian anemia. Penelitian ini tidak mendapatkan adanya hubungan variabel-variabel independenyang diteliti dengan kejadian anemia.
Potensi Kemunculan Kembali Malaria Di Kabupaten Pangandaran
Authors: Hakim Lukman , Wahono Tri , Ruliansyah Andri , Kusnandar Asep Jajang
Published: October 2019

Although at present the number of malaria cases in Pangandaran is low, a time will increase again because malaria is a re-emerging disease. To determine the potential of reemergence of malaria, have done the research by identifying the pattern of disease, the malaria parasite, knowledge, attitudes and behavior as well as the mobilization of the population, and environmental factors and entomology malaria. The collected data were analyzed to determine the potential reemergence of malaria using dynamic analysis system. Identification of the parasitological are showed that all of the blood sample results were all negative Plasmodium spp  The results of interviews showed that the state of knowledge in the category malaria mostly not good (64.58%), 28.23% of respondents have a regular ART wander, 11.53% of them never came home ill with malaria. While the environmental status of settlement of respondents relation to malaria transmission mostly (67.99%) is not good. Survey entomologist discovered 1,037 mosquitoes which consists of 8 species of Anopheles spp. Most are An. vagus (67.89%) while the least is An. indefinitus. Based on the methods of arrest, most in catching a rest at home (98.46%) and least is the catch UOD (0.10%). The analysis data had been resulted that highest leverage effect on the reemergence of malaria is the mobilization of the population. So that be advised to monitoring the population migrating to and from endemic areas, especially outside Java through migration survey.
Evaluasi Toksisitas Ekstrak Metanol Daun Jeruk Nipis (Citrus aurantifolia) terhadap Kematian Larva Nyamuk Aedes aegypti
Authors: Ardianto Hebert , Hamidah Hamidah
Published: October 2019

The vector-borne diseases transmitted by the mosquito of Aedes aegypti are considered causes of serious health problems. Moreover, the used of chemical insecticides for Ae. aegypti control has resulted in resistance in mosquito populations and environmental problem. The aims of this study are to evaluate the toxicity of methanol extract (CH3OH) from key lime leaves against Ae. aegypti larvae after 24 hours exposure. This was experimental laboratory study, with six treatments and five replicates. Larvae mortality was observed after 24 hours exposure. Then, data were analyzed by descriptive analyze and probit. visualization of the damage that occurs in the body was observed through microscope. The result showed that mortality of larvae increased with an increase of the concentration of extract. LC50 and LC99 of the extract are 2,197 ppm and 4,266 ppm. The extract can cause morphological damages of larvae, such as head lost, neck elongation, exo-skeleton lost, abdomen transparent, digestive tract full of extract, and loss of setae on the side of the body. In conclusion, citrus aurantifolia leaves methanol extract cause mortality and morphological damages of larvae
Pengetahuan, Sikap dan Riwayat Pengendalian Vektor di Daerah Endemis Demam BerdarahDengue Kota Bandung
Authors: Prasetyowati Heni , Fuadzy Hubullah , Astuti Endang Puji
Published: October 2019

Dengue vector control needs active participation of community so it must be supported with goods dengue knowladge.  The purpose of this research is to know the difference of knowladge and attitute in Bandung city community toward effort of dengue vector control in case and control group.  This case-control study used ratio 1: 2.  Number case of dengue is 261 and number of control is 522.  Research location are ini health center area with hight dengue case ie Dago, Sekejati, Kopo, Cipamokolan.  Responden ages grouped in range of 40-60 years, while the last education respondents are greduated from junior and senior high school.  The result shows that there is significant different of knowladge between case and control (p-value 0.015) and  no significant different in attitude variable (p-value 0,520).  Vector control efford is different between two group in active eradication of mosquitoe breeding place (p-value 0.005) and the used of mosquito net (0.008).  The odd ratio test result showed that knowladge variable (OR 1,410) and eradication of mosquitoe breeding place (OR1.719) are related to vector control efforts.  Still needs enhance health promotion regarding vector control efforts in house hold environment as well as understanding of dengue, and optimizing program “one house one larva’s monitor
MOVIMENTOS RELIGIOSOS TRANSNACIONAIS: DE REDES A TERRITÓRIOS
Authors: Knibbe Kim
Published: October 2019

Este artigo, baseado em trabalho de campo multi-situado, descreve igrejas

pentecostais transnacionais originárias da Nigéria. A religião é frequentemente descrita

como desterritorializada, devido aos processos de globalização. Neste artigo, a autora

argumenta que territórios, localidades e lugares são em realidade muito importantes

para o pentecostalismo nigeriano transnacional, e que igrejas pentecostais africanas, em

geral, constituem territórios e lugares de novas maneiras, assim como acrescentam novas

dinâmicas às cidades. O poder persuasivo de criar geografas tangíveis ancoradas em prédios

reais, porções de terra e instituições é importante para entender como o pentecostalismo

transnacional está impactando as esferas públicas ao redor do mundo.
PARA ALéM DAS FRONTEIRAS NACIONAIS: TRANSNACIONALIZAÇÃO E INTERNACIONALIZAÇÃO RELIGIOSA, NOVAS FORMAS DE “SER” E “ESTAR” NA POLíTICA
Authors: Meirelles Mauro
Published: October 2019

O presente trabalho se propõe a realizar um estudo comparativo acerca do

imaginário político e religioso que se faz presente em três capitais cisplatinas, a saber,

Porto Alegre, Buenos Aires e Montevidéu. Para isto, centramos nossa análise nos fuxos de

redes de lideranças religiosas pentecostais e afro-brasileiras que recobrem a bacia do Rio da

Prata e no enquadramento que estes atores religiosos fazem acerca da relação entre religião

e política. Especifcamente, nos interessa pensar a religião e as formas pelas quais ela se

transnacionaliza, produzindo um imaginário coletivo com diferentes representações acerca

do político e do religioso em função de diferentes marcos interpretativos do real.
O PROFETISMO DE JOÃO MARIA NOS DISCURSOS CONTEMPORÂNEOS
Authors: Welter Tânia
Published: October 2019

Este é um estudo sobre os discursos contemporâneos a respeito do Profeta São João Maria em Santa Catarina. Partindo da noção de discurso como ação humana significativa, afirmo que os discursos a respeito de João Maria são resignificados pelas pessoas a partir de sua cultura histórica, possuem temporalidade, expressam algo e são disponibilizados para outras leituras e interpretações. A partir de critérios próprios, as pessoas legitimam João Maria como profeta e este se torna adequado na interpretação de mundo, no controle da indeterminação do mundo, para anunciar e acabar com o mal, reagir contra aquilo que não está de acordo com sua cultura ou anunciar o mundo desejado.
USARSKI, Frank. O Budismo e as outras; encontros e desencontros entre as grandes religiões mundiais. Aparecida, SP: Idéias e Letras, 2009, 304 p.
Authors: Lopes José Rogério
Published: October 2019

Resenha: USARSKI, Frank. O Budismo e as outras; encontros e desencontros entre as grandes religiões mundiais. Aparecida, SP: Idéias e Letras, 2009, 304 p.
TURNER, VICTOR. DRAMAS, CAMPOS E METÁFORAS. NITERÓI: EdUFF , 2008. 278 P.
Authors: Ranquetat Júnior Cesar
Published: October 2019

Resenha: TURNER, VICTOR. DRAMAS, CAMPOS E METÁFORAS. NITERÓI: EdUFF , 2008. 278 P.
“Pé na Estrada”: Uma etnografia da circulação transnacional de peregrinos
Authors: Brum Ceres Karam
Published: October 2019

Neste texto desejo apresentar algumas reflexões sobre o Caminho das Missões e o Caminho de Santiago de Compostela explorando as possibilidades de realizar uma etnografia comparada entre os dois caminhos. Para tanto, pretendo utilizar um conjunto de observações efetuadas sobre estas peregrinações a partir de dados etnográficos relativos ao Caminho das Missões, obtidos em 2003 e Caminho de Santiago, em 2004. Também desejo enfocar momentos mais recentes relativos às experiências etnográficas citadas: os processos de elaboração e as significações das redes de “peregrinos” em um grupo de caminhada, observados na região de Santa Maria, entre 2006 e 2008 a partir de minha trajetória pessoal em observação participante.