bluuebunny/crossref_metadata_2025 huggingface dataset:
Catalyst-Controlled Directing Group Translocation in the Site Selective C–H Functionalization of 3-Carboxamide Indoles and Metallocarbenes
Authors: Gu Kuang , Hall Mary , Tucker Zachary , Durling Gregory , Ashfeld Brandon
Published: May 2024

Complementary methods toward the selective functionalization of indole and oxindole frameworks employing an alternative strategy in heteroaryl C–H functionalizations are presented herein. This work focuses on a catalyst-controlled, site selective C–H activation/functionalization of 3-acyl indoles, wherein an amide serves as a robust and versatile directing group capable of undergoing concomitant 1,2-acyl translocation/C–H functionalization in the presence of a RhI/AgI co-catalysts to provide the cross-coupled adducts in high yields. In contrast, the use of IrIII/AgI catalysts subverted the 1,2-acyl migration to afford the corresponding C2-functionalized products in good to excellent yields. A notable feature of the catalyst systems was the exceptional level of site selectivity observed in which the corresponding C–H functionalized indoles were obtained exclusively. Mechanistic experiments indicate a concerted 1,2-acyl migration step and indole metallation occurring through an electrophilic aromatic substitution process.
Total synthesis of a peptide diatom sex pheromone bearing an unusual sulfated aspartic acid
Authors: White Andrew M. , Schwartz Brett D. , Gardiner Michael G. , Malins Lara R.
Published: May 2024

The peptide Sex Inducing Pheromone SIP+ bearing an unusual sulfated aspartic acid residue induces sexual reproduction in diatom populations. Herein, we report the first total synthesis of SIP+ using both a sulfated building block approach and a SPPS compatible late-stage sulfation strategy to assemble the natural product. The modular approaches provide concise routes to useful quantities of the natural product for future SAR investigations examining the role of SIP+ in diatom biology.
The impact of physical exercise on the endocrine system in men: A review
Authors: Berkovskaya Marina A. , Elmurzaeva Asya A. , Edaev Api  L.-A. , Selakhov Timerlan  Yu. , Tokaev Habib  M. , Gurova Irina  D.
Published: May 2024

The endocrine system regulates many functions of the human body to maintain optimal performance and homeostasis of various organs and systems. Playing sports and various physical activities changes the regulatory function of the endocrine organs in the form of successive phases, and the magnitude of the response depends on the intensity and duration of the physical stress exerted. Hormonal regulation during physical activity facilitates the adaptation of the functional activity of the cardiovascular system, the activation of energy depots, and the maintenance of adequate tissue hydration. Physical activity leads to an increase in the production of growth hormone, insulin-like growth factor-1, total and free testosterone, which enhances the anabolic reactions of the body. It is important to understand the relationship and impact of physical activity on the functioning of the endocrine system for the development of physical exercise’s complexes, patient rehabilitation, research and treatment of endocrine disorders. The effect of physical activity on the endocrine system for women has been studied to a greater extent, in contrast to men, where the data is contradictory. Therefore, in this article we will highlight the features of various endocrine organs and hormones during sports activities in men.
Effectiveness of use of group B vitamins in patients with diabetic polyneuropathy: A review
Authors: Trukhan Dmitry I. , Druk Inna V.
Published: May 2024

Recent decades have been marked by a rapid increase in the number of patients suffering from diabetes. The development and progression of complications of the disease have the greatest impact on the life prognosis of patients with diabetes mellitus. One of the common complications of diabetes mellitus is diabetic polyneuropathy. According to expert estimates, diabetic polyneuropathy develops in 50% of patients with diabetes mellitus and in 10–30% of patients in a prediabetic state. In domestic clinical recommendations and algorithms, the treatment of diabetic polyneuropathy is considered only in terms of drugs used to treat the painful form of diabetic polyneuropathy. In the recommendations of international experts, pathogenetically oriented pharmacotherapy (alpha-lipoic acid and benfotiamine) occupies an important place. As part of the review, we examined the use of B vitamins for the treatment of diabetic polyneuropathy. We searched for relevant sources in the PubMed and Scopus information databases, including the time period up to 12.04.2024. Experience with the use of B vitamins shows that their maximum effectiveness is achieved when they are used in combination, which is due to the complementary effect of each individual vitamin. The use of a combination of vitamins B1, B6 and B12 for diabetic polyneuropathy normalizes reflex reactions, helps eliminate sensitivity disorders, increases the speed of conduction along nerve fibers, and has a moderate analgesic effect.
Nanobodies as novel tools to monitor the mitochondrial fission factor Drp1
Authors: Froehlich Theresa , Jenner Andreas , Cavarischia-Rega Claudia , Fagbadebo Funmilayo O , Lurz Yannic , Frecot Desiree I , Kaiser Philipp D , Nueske Stefan , Scholz Armin M , Schäffer Erik , Garcia-Saez Ana J , Macek Boris , Rothbauer Ulrich
Published: May 2024

In cells, mitochondria undergo constant fusion and fission. An essential factor for fission is the mammalian dynamin-related protein 1 (Drp1). Dysregulation of Drp1 is associated with neurodegenerative diseases including Parkinson’s, cardiovascular diseases and cancer, making Drp1 a pivotal biomarker for monitoring mitochondrial status and potential pathophysiological conditions. Here, we developed nanobodies (Nbs) as versatile binding molecules for proteomics, advanced microscopy and live cell imaging of Drp1. To specifically enrich endogenous Drp1 with interacting proteins for proteomics, we functionalized high-affinity Nbs into advanced capture matrices. Furthermore, we detected Drp1 by bivalent Nbs combined with site-directed fluorophore labelling in super-resolution STORM microscopy. For real-time imaging of Drp1, we intracellularly expressed fluorescently labelled Nbs, so-called chromobodies (Cbs). To improve the signal-to-noise ratio, we further converted Cbs into a “turnover-accelerated” format. With these imaging probes, we visualized the dynamics of endogenous Drp1 upon compound-induced mitochondrial fission in living cells. Considering the wide range of research applications, the presented Nb toolset will open up new possibilities for advanced functional studies of Drp1 in disease-relevant models.
Low Cost Water Purification: Harnessing Adsorbents for Sustainable Treatment Solutions
Authors:   Professor, Department of Civil Engineering, Sri Bharathi Engineering College for Women, Pudukkottai, INDIA, Ebenezer A.Vimala , M.A. Raja ,   Assistant Professor, Department of Civil Engineering, Meenakshi Sundararajan Engineering College, Chennai, INDIA
Published: May 2024

Water is essential for life, yet millions lack access to clean drinking water. Low-cost treatment methods are crucial to ensure equitable access to safe water and prevent waterborne diseases in underserved communities. The study devised a 12-liter water filter utilizing pebbles, sand, and adsorbents biochar of Julifora, cashew nut shell and rice husk. Results demonstrated the filter's effectiveness in sustaining pH levels while reducing chloride, fluoride, hardness and alkalinity. Particularly noteworthy was the capacity of cashew nut biochar to efficiently adsorb chloride, fluoride, hardness and alkalinity as 27%, 37%, 38% and 43% respectively. This indicates its promising role as an adsorbent for water purification. The findings underscore the potential of the designed filter in improving drinking water quality by mitigating contaminants. Further refinement and optimization of the filter could enhance its efficacy in meeting stringent water quality standards, addressing the pressing need for accessible and safe drinking water globally.
Empowering Mental Well-being: AI-guided Self-Recognition and Support
Authors:   Department of Information Technology, Greater Noida Institute of Technology (Engg. Institute), Greater Noida, INDIA, Kumar Nikhil , Singhal Dr.Vikas ,   Head,Department of Information Technology, Greater Noida Institute of Technology (Engg. Institute), Greater Noida, INDIA
Published: May 2024

In an era marked by the convergence of technology and mental health, the integration of artificial intelligence (AI) holds promise for revolutionizing how individuals engage with their own well-being. This abstract explores the concept of AI-guided self-recognition and support as a transformative approach to empower mental wellness. Through sophisticated algorithms, AI can analyze diverse data streams, including digital behaviors and physiological markers, to detect subtle shifts indicative of mental health challenges. Leveraging this capability, AI becomes a proactive companion in individuals' journeys toward self-awareness. Furthermore, AI augments traditional support systems by offering personalized interventions tailored to individual needs and preferences. From empathetic chatbots providing emotional solace to curated resources and mindfulness exercises promoting resilience, the AI ecosystem becomes a versatile toolkit for mental health enhancement. Importantly, this paradigm shift emphasizes continuous learning and refinement, ensuring that interventions evolve in tandem with users' experiences and feedback. However, the implementation of AI-guided mental wellness initiatives necessitates careful consideration of privacy and ethical principles. Striking a balance between data utilization and user confidentiality remains paramount to fostering trust and engagement. Moreover, transparency in AI algorithms' functioning and accountability in decision-making processes are imperative to uphold ethical standards.
Prediction of RUL of lubricating oil based on Deep Learning Technique
Authors:   Department of Information Technology,  Greater Noida Institute of Technology (Engg. Institute), Greater Noida, INDIA, Jaiswal Kajal , Kumar Pathak Kishan ,   Department of Information Technology, Greater Noida Institute of Technology (Engg. Institute), Greater Noida, INDIA, Agarwal Deepak ,   Department of Information Technology, Greater Noida Institute of Technology (Engg. Institute), Greater Noida, INDIA
Published: May 2024

This study uses condition monitoring (CM) to determine the lubricating oil's remaining usable life (RUL). First, Atomic emission spectroscopy (AES) was used to determine the lubricating oil's element makeup and content. Under use were quantitatively examined. The precision and efficacy of the RUL prediction model might be diminished in light of the wide range of oil data acquired using AES. A thorough it is recommended to screen oil data using a method for choosing parameters based on correlation analysis, lubricant degradation analysis, and information entropy. In order to address this issue. The lubricant's RUL prediction model was then developed using a support vector machine (SVM). It is shown that the SVM prediction model's efficacy and accuracy by contrasting the experimental findings with the prediction model's output data.
The Indicators Of Village Administrative Officers Understanding Of Siskeudes: A Literature Study
Authors: Pawiro Yulianti , Janie Dyah N. A.
Published: May 2024

This research is grounded by the enforcement of Village Law and disbursement of Village Fund. The substantial amount of Village Fund demands a more complex accountability. The limited time and inadequate human resources available, this village fund is susceptible to leakage which may be caused by either errors or irregularities.

Using literature study method, this research attempts to explore the factors potentially related to village administrative governance and understanding of Village Financial System or Sistem Keuangan Desa (Siskeudes).

The results indicate that there are five resultant variables, namely: understanding of Siskeudes, village financial management principles, special fund distribution or Village Fund Allocation (Alokasi Dana Desa/ADD), village financial administration, village financial reporting and accountability and understanding of village-owned property report. This research still needs to be developed further to test the validity of each variable generated in this research.
Analyzing the Impact Of Traditional Market Relocation In Surrounding Traders And Communities (Case Study Of Demak Mranggen Markets)
Authors: Soelistiyono Anitiyo , Adrianto Andhy Tri , Kurniawati Emaya
Published: May 2024

Traditional markets are markets that are built and managed by local governments. Relocation of a transfer of supporting facilities and infrastructure activities from one place to another in order to enhance the security, comfort and legality factors.Mranggen traditional market is one of the markets located in the village of Mranggen which is increasingly experiencing an increasing number of traders. For this reason, the Demak Regency Government decided to relocate the market, one of them is the traditional Mranggen market, the government's purpose of relocating Mranggen's traditional market to tidy up the former market which had not been neatly arranged. Mranggen's market relocation had an impact or pros and cons for traders and the surrounding community. The problem in this study is the impact of market relocation of Mranggen's traditional market relocation to traders in the surrounding community. The aim of the study was to determine the impact of Mranggen's traditional market relocation to both traders and the surrounding community with market relocation.

The research design used in this study is a holistic single case study. This study uses a qualitative approach. The types and sources of data used in this study are primary data and secondary data. The object of the research was conducted at the temporary shelter of Mranggen village. Informants are traders and communities around the shelter. Data collection techniques with triangulation.As for eclectic data analysis techniques. In this study, the validity of the research data was tested by credibility, transferability, dependability test, and confirmability test.

The results of our research on the impact of relocation on product quantity is the reduction in product quantity ranging from 30% to 50%. With regard to operating hours the impact of this relocation is a reduction in operating hours of only 6-8 hours per day. For the position of the stall The inconvenience of the stall position, the stinging smell of garbage, and when the rainy season often floods and lacks security. In terms of ease of reaching the location, the traders complained about the location of the remote relocation and the narrow road to relocation which affected the consumers' desire to buy. With this relocation, sales turnover has decreased from 75,000-250,000/day.
ANALISA PERHITUNGAN SUSUT TEKNIS DI PT. PLN (PERSERO) RAYON SINGKIL
Authors: Syukri Syukri , Muliadi Muliadi , Akbar Ali
Published: May 2024

ABSTRACT

PT. PLN (Persero) Rayon Singkil is working hard to carry out activities to reduce energy losses in the distribution network. There are two types of energy losses in the distribution network, namely technical losses and non-technical losses. This study of technical losses in Singkil rayon is discussed by approaching distribution asset data and load conditions using the Microsoft Excel program so that all data can be processed. Calculation of JTM losses, transformer losses, JTR losses, SR and APP losses. So the results obtained in Singkil Rayon with 4 feeders, namely in January 2023 were 10.4% with a composition of technical losses of 7.7% and non-technical losses of 2.7%, in February 2023 distribution losses were 8.6% with a technical loss composition of 7.8% and non-technical loss of 0.8%. Based on the calculation results, it makes it easier for PT. PLN (Persero) Rayon Singkil in analyzing and evaluating efforts that can be made to reduce distribution losses so that they become more efficient.

                                                                                                 

Keywords: Distribution system, Electrical energy, Energy losses, Technical losses, Non-technical losses.

 

ABSTRAK

PT. PLN (Persero) Rayon Singkil sedang berupaya keras melaksanakan kegiatan-kegiatan dalam hal penekanan susut energi pada jaringan distribusi. Susut energi pada jaringan distribusi ada dua yaitu susut teknis dan susut non teknis. Kajian mengenai susut teknis pada rayon singkil ini dibahas dengan cara pendekatan data aset distribusi dan kondisi beban dengan menggunakan program Microsoft Excel sehingga semua data dapat diproses. Perhitungan susut JTM, sussut trafo, susut JTR, susut SR dan APP. Maka hasil yang didapatkan pada Rayon Singkil dengan 4 penyulang yaitu pada bulan Januari 2023 sebesar 10,4 % dengan komposisi susut teknis sebesar 7,7 % dan susut non teknis sebesar 2,7 %, pada bulan Februari 2023 susut distribusi sebesar 8,6 % dengan komposisi susut teknis sebesar 7,8 % dan susut non teknis sebesar 0,8 %. Berdasrkan hasil perhitungan memudahkan PT. PLN (Persero) Rayon Singkil dalam menganalisa dan mengevaluasi terhadap upaya yang dapat dilakukan untuk menurunkan susut distribusi sehingga menjadi lebih efisien.
CRAFTING INNOVATION: NURTURING CREATIVE THINKING IN CAD ENGINEERING FOR FUTURE BREAKTHROUGHS
Authors: Андрушко А. М. , Лобур М. В.
Published: May 2024

In the ever-evolving landscape of Computer-Aided Design (CAD) engineering, the demand for groundbreaking solutions and innovative designs necessitates a harmonious blend of technical expertise and creative thinking. Recognizing the growing importance of creativity, this article addresses the need for a transformative approach that goes beyond traditional linear problem-solving methods within CAD engineering. The primary objective is to unravel the intricate relationship between technical proficiency and creative thinking, exploring the nuances of creativity in the CAD engineering context. By delving into the distinct realms of linear and lateral thinking, the article aims to provide a comprehensive understanding of the creative process and principles specific to CAD engineering. The exploration is structured across several subsections, beginning with the definition of creativity tailored to CAD engineering and a detailed analysis of linear and lateral thinking. The creative process and principles are dissected, laying the groundwork for practical insights into fostering creativity at educational institutions and individual levels. Drawing inspiration from realworld examples, the article outlines actionable steps and strategies to enhance creative thinking skills for CAD engineers. The findings reveal that a holistic integration of creativity is imperative for CAD engineers to navigate the complexities of design challenges effectively. By understanding the roles of technical universities, educators, and individuals, the article provides a roadmap for fostering a culture of creativity within CAD engineering. The article derives its novelty from synthesizing theoretical frameworks with practical insights, bridging the gap between conceptual understanding and actionable strategies. The incorporation of HP’s innovative culture rules adds a distinctive layer, offering tangible principles that resonate with the spirit of creativity in a dynamic engineering environment. The practical value lies in empowering CAD engineers with a toolkit that extends beyond technical skills, fostering a mindset conducive to innovation. By emphasizing interdisciplinary collaboration, structured creative techniques, and continuous learning, the article provides tangible strategies for engineers seeking to enhance their creative thinking skills. While the article comprehensively explores the current landscape, there are avenues for further investigations into the long-term impact of creativity in CAD engineering. Future research could delve deeper into assessing the effectiveness of specific strategies in fostering creativity and explore how emerging technologies influence the creative aspects of CAD design. Additionally, examining the intersection of creativity and sustainability within CAD engineering could be an intriguing area for further exploration.
Analysis of the Effect of Integrated Extended Care Model in Improving the Quality of Life of Elderly Patients with Type 2 Diabetes Mellitus
Authors: Liu Lili
Published: May 2024

Objective: To analyze the impact of an integrated extended care model on improving the quality of life of elderly patients with Type 2 Diabetes Mellitus (T2DM). Methods: A total of 176 patients admitted to the hospital from March 2015 to February 2018 were selected and randomly assigned to an observation group and a control group, with 88 patients each. The control group implemented conventional nursing interventions, and the observation group carried out an integrated extended-care model. The level of glycemic control, quality of life, and daily medication adherence between both groups were compared. Results: The observation group showed significant improvement in the level of glycemic control, and their fasting blood glucose, 2-hour postprandial blood glucose, and glycated hemoglobin levels were significantly lower as compared with those in the study group (P < 0.05). The quality of life of the patients in the observation group was higher than that of the control group (P < 0.05). The observation group had a higher compliance score (95.48 ± 7.45) than the control group (81.31 ± 8.72) (t = 8.909, P < 0.05). Conclusion: The integrated extended care model allows patients to receive comprehensive and individualized nursing services after discharge, which improves the effect of drug therapy and the quality of life of patients.
Community Service Activities: Realizing Sustainable Social Care Through the Kindergartens Togetherness
Authors: Nuringsih Kartika , Edalmen Edalmen , Lumingkewas Vicly G.
Published: May 2024

As an effort to realize children's concern for each other, an activity was carried out with the union of parents and teachers at one of the kindergartens in Beji Timur, Depok. This moment continues previous activities with the aim of being a solution to maintain the sustainability of social activities at Raudhatul Athfal Taufiqurrahman. Using participatory action research, the approach involves providing dissemination to children about the importance of sharing with others. The activity was carried out in the month of Ramadan, attended by 30 students with the school principal, accompanying teachers, and representatives of the student’s parents. At this event, the children distributed gifts to orphans and people in need around the school. With this action, children experience sharing with others so that the support of parents and teachers is expected to be touched and interested in social activities. This effort is related to the formation of good character in children so that collaboration with stakeholders will support the sustainability of this education. The togetherness of several parties is a form of subjective norm so that children become more interested in social activities. Meanwhile, messages reminded by teachers and mothers at home can form a positive attitude towards social activities. In this way, children can assess this activity as a positive experience, thereby fostering awareness and prosocial behavior in their adult years. This is in line with the sustainable development goals to ensure development progress for children. As a recommendation, further activities can be carried out with orphanages.
Partisan Conflict and Uncertainties Spillover in the United State.
Authors: Alola Andrew , Akadiri Seyi Saint , Ajmi Ahdi
Published: May 2024

Given the increasing political polarization in the United States, especially on cogent issues of climate change, health policy, immigration, and recently the handling of the Coronavirus pandemic, the current study divulged further on the link between policy divides and partisan conflict. In the context, we employed the Diebold and Yilmaz index model to examine the potential spillover effect among partisan conflict (PC), economic policy uncertainty (EPU), fiscal policy (FP), and monetary policy (MP) over the period from January 1996 to June 2020 for the case of the United States. Importantly, the result posits a total spillover index (interconnectedness) of 30.04% among the examined variables, thus showing that shock transmission exists among these variables. In addition, the EPU transmits the largest share of shock (56.78%) to PC, FP, and MP, thus illustrating that the EPU is the only net giver of potential shock but with a net spillover of (+) 12.325%. Moreover, with the largest spillover index of 84.569%, PC directly contributes the largest shock to the EPU (6.691%), which is followed by a direct 4.608% to fiscal policy and a lower shock of 0.526% to monetary policy. Apart from making a significant contribution to the existing literature on partisan conflict in the United States, this study further highlighted the grey area to pursuing more inclusive democratic discourse and dialogue among the country’s social, cultural, and political representations.
Elektrikli araçların hibrit enerji depolama sistemleri için akciğer performansına dayalı optimizasyon algoritması temelli kontrolör geliştirilmesi
Authors: Boyar Aydın , Kabalcı Yasin , Kabalcı Ersan
Published: May 2024

Elektrikli araçlar, enerji tasarrufu yetenekleri ve egzoz kirliliğinin olmaması gibi avantajlarla fosil yakıtlı araçların yerini alma potansiyeline sahiptir. Ancak, saf elektrikli araçlar hâlâ kötü enerji tüketimi, uzun şarj süreleri ve kısa batarya menzili gibi kısıtlamalarla karşı karşıyadır. Bu nedenle elektrikli araçlarda hibrit enerji depolama sistemlerinin kullanılması yaygınlaşmaktadır. Bu çalışmada, akciğer performansına dayalı optimizasyon algoritması kullanılarak yeni bir kontrolör tasarımı gerçekleştirilmiş ve elektrikli araçların hibrit enerji depolama sistemlerinin enerji tüketim talepleri tasarlanan sistem ile optimize edilmiştir. Önerilen sistemin performans sonuçları literatürdeki diğer enerji yönetim sistemleri ile karşılaştırılmış ve bu çalışma ile önerilen sistemin önceki yöntemlerden çok daha üstün olduğu, tipik olarak ise enerji tüketimini %21.86 oranında düşürdüğü sonucuna ulaşılmıştır.
Optimising Bcrypt Parameters: Finding the Optimal Number of Rounds for Enhanced Security and Performance
Authors: Listiawan Indra , Zaidir Zaidir , Winardi Sugeng , Diqi Mohammad
Published: May 2024

Recent advancements in the field of information security have underscored the imperative to fine-tune Bcrypt parameters, particularly focusing on the optimal number of rounds as the objective of research. The method of research is a Brute Force Search method to find the optimal value of bcrypt rounds. The primary focal point of optimization lies in the number of Bcrypt rounds due to its direct impact on security levels. Elevating the number of rounds serves to fortify the security of the Bcrypt algorithm, rendering it more resilient against brute-force attacks. The execution of the Bcrypt rounds in the experimental method mirrors real-world scenarios, specifically in the evaluation of Bcrypt parameters with a focus on entropy assessment of the hash. The selection of the number of rounds should consider the specific needs of the system, where security takes precedence or faster performance is a crucial factor.
Impact of Wolf Thresholding on Background Subtraction for Human Motion Detection
Authors: Pambudi Elindra Ambar , Nurhidayat Muhammad Ivan
Published: May 2024

Series of motion detection based on background subtraction there is an image segmentation stage. Thresholding is a common technique used for the segmentation process. There are two types that can be used in thresholding techniques namely local and global. This research intends to implement local adaptive wolf thresholding as the threshold value of the background subtraction method to detect motion objects. The proposed method consists of the reading frame, background and foreground initialization of each frame, preprocessing, background subtraction, wolf thresholding, providing a bounding box, and running frame sequentially. Based on MSE and PSNR obtained on four videos, it has shown that wolf thresholding has succeeded in outperforming of global threshold.
Liderazgo de la administración general en un corporativo privado
Authors: Rosiles-Villalobos Abraham , González-Montejo Claudia , Prieto-Urbano Jesús Alberto
Published: May 2024

Hoy en día las organizaciones necesitan ser administrados por líderes capaces de encaminar al éxito a cada uno de sus colaboradores, el presente trabajo de investigación tuvo como objetivo identificar el estilo de liderazgo que predomina en la administración general del corporativo VYA Asesores ubicado en la ciudad de Acayucan, Veracruz; para ello se aplicó un censo a 25 colaboradores utilizando el instrumento de recopilación Multifactor Leadership Questionarie (MLQ) diseñado por Bass & Avolio y adaptado al contexto latinoamericano por Vega & Zavala (2004). Los principales resultados indican que el nivel de Liderazgo Transformacional (LTF) es el predominante y puntuó 4.15/5; destacando la subvariable Carisma/ Inspiracional, jerarquía que a decir de Bass & Avolio el líder brinda a los subordinados un sentido de propósito claro, visión de futuro, conductas que sirven de modelos de rol asumiendo siempre actitudes congruentes entre lo que dice y lo que hace. Como recomendación se sugiere que la administración general concluya su proceso de reestructuración organizacional y que en este contemple un programa de incentivos para sus colaboradores.
Trade – Off Fungsi Produksi Pertanian dan Fungsi Konservasi Lahan Gambut
Authors: Tarigan Surya A
Published: May 2024

Pemanfaatan lahan gambut perlu dilakukan dengan hati-hati karena fungsinya sangat penting dalam pengaturan fungsi hidrologis baik mengurangi potensi banjir pada musim penghujan maupun kebakaran pada musim kebakaran. Permanfaatan lahan gambut sering menjadi polemik karena lanskap gambut mempunyai fungsi produksi dan fungsie ekologis. Kedua fungsi tersebut berkompetisi dan masing-masing pihak menganggap satu fungsi lebih penting dari fungsi lain. Namun demikian terdapat trade-off untuk rekonsilisiasi kompetisi kedua fungsi tersebut. Salah satu strategi untuk mencapai rekonsilisiasi tersebut adalah dengan menilai total ecosystem services (TES) dari fungsi produksi dan fungsi ekologi. Policy brief ini menggunakan kajian TES dengan mempertimbangkan 2 hal penting yang selama ini belum dimasukkan dalam kajian TES yaitu a) pemanfaatan lahan gambut untuk perkebunan pada lokasi penanamannya tidak memenuhi kriteria kesesuaian lahan yang ditunjukan oleh produksi yang dibawah standar maka perlu diarahkan untuk regenerasi alami untuk meningkatkan fungsi ekologis, dan 2) subsidensi yang tinggi pada pemanfaatna lahan gambut dapat mengakibatkan potensi genangan permanen sehingga perlu dimasukan dalam kajian TES.
Perdagangan Internasional, Bagaimana dengan Arah Kebijakan Komoditas Pertanian Indonesia?
Authors: Irwandi Putra
Published: May 2024

Kebijakan perdagangan internasional yang telah terjadi saat ini adalah salah satu aspek penentu dalam perwujudan kedaulatan pangan nasioal yang strategis dan berdampak pada peningkatan kesejahteraan petani lokal di Indonesia. Hal ini terbukti dari data dari Kementerian pertanian mencatat bahwa tahun 2017-2021 nilai ekspor Indonesia mencapai angka 26,370 miliar dolar US dengan rata-rata peningkatan sebesar 7,83 persen pertahun. Sehingga Badan Pusat Statistik mencatat bahwa selama dua periode sektor pertanian memberikan kontribusi dalam pertumbuhan laju pertanian sebesar 6,23% pertahun
Dilain sisi, Ketergantungan impor pangan nasional meningkat sebanyak 2 kali lipat terlihat pada komoditas beras sebesar 10 persen, jagung 201%, kedelai 55% dan gula sebesar 50%. Padahal komoditas-komoditas yang ada telah menyerap masing-masing 23 juta, 9 juta, 2,5 juta, dan 1 juta rumah tangga atau sebesar 68% dari total rumah tangga di Indonesia
Salah satu kebijakan WTO sebagai lembaga tertinggi perdagangan dunia memiliki perjanjian yang didalamnya termasuk perjanjian berbasis pertanian atau yang dikenal dengan AOA (Aggrement on Agriculture). AOA ini merupakan salah satu perjanjian pertanian yang tidak dapat dipisahkan dari dokumen WTO. Terdapat tiga pilar utama pembangun dokumen WTO yakni : 1. Akses pasar, 2. Subsidi Domestik, dan 3. Subsidi Ekspor. Namun faktanya, kebijakan AOA WTO menggangu aktivitas perdagangan negara-negara berkembang termasuk Indonesia
The Habitat Suitability Modelling of Rhinoceros Hornbills (Buceros rhinoceros) in Java Island, Indonesia
Authors: Setiawan Taufik , Prasetyo Lilik Budi , Mulyani Yeni A. , Jarulis
Published: May 2024

Rhinoceros hornbills (Buceros rhinoceros) are a bird species belonging to the Bucerotidae family, which is vulnerable based on the IUCN red list of species. This is due to habitat fragmentation, which reduced the Rhinoceros hornbill habitat on Java. Efforts and strategies are needed to maintain Rhinoceros hornbill habitats. Information on the suitability of the Rhinoceros hornbill habitat on Java Island is required to develop a Rhinoceros hornbill conservation strategy. This study aimed to determine a habitat suitability model that produces the highest accuracy, analyze hornbill habitat suitability, and identify environmental variables that affect the existence of rhinoceros hornbills. Habitat suitability models were processed using three algorithms: random forest, support vector regression, and MaxEnt. The data used to model habitat suitability were presence and environmental variables. The model was evaluated using various accuracy measures, namely overall accuracy, sensitivity (sn), specificity (sp), Area Under Curve (AUC), and kappa coefficient. The resultsof model processing showed that the random forest algorithm produced the highest average accuracy of 0.74. The most important environmental variables for the habitat suitability model were the distance from the road (16.62%), distance from the forest (12.73%), and land cover (12.47%). The habitat suitability model was divided into three classes: low suitability, covering 75,048 km2 (55.94%); medium suitability, covering 52,911 km2 (39.44%); and high suitability, covering 6,213 km2 (4.63%). The results of the habitat suitability model showed that the habitat suitability class was the smallest in the area.
Etiology and classification of gummy smile as a key to successful management and aesthetically good result
Authors: Volokovaya E. , Slabkovskaya A.
Published: May 2024

Smile aesthetics is an important aspect of orthodontic treatment. This review presents data from international and russian studies about gummy smile etiology, classification and available treatment. Given the lack of a unified classification of gummy smile, treatment outcomes may not always be predictable. Based on the analysis of available data about etiology, classification, and treatment options of the gummy smile, it is possible in the future to create a new, more complete system for evaluating smile parameters. This data will help to make more convenient scheme for determining successful management of a patient with gummy smile and obtaining aesthetically good results.
Efficacy of METFORMIN and sibutramine therapy in patients with infertility associated with metabolic syndrome
Authors: Martina M. , Chilova R. , Sokova E. , Maslov S. , Poznyak M. , Sevastyanov G.
Published: May 2024

The increasing interest of the scientific medical community in the problem of metabolic syndrome (MS), its timely diagnosis and treatment, is associated with a steady increase in the incidence of MS. The most alarming thing is that the majority of patients are people of active work-related and reproductive age. According to scientists, the frequency of MS is expected to increase by 50% in the next 20 years, which means that in the absence of effective prevention and treatment of MS, industrialized countries risk facing a social and demographic catastrophe. In addition to non-drug treatments for MS (diet, exercise, etc.), metformin and sibutramine are recognized as extremely important drugs of choice in the medical treatment of MS.
Emollients in psoriasis therapy
Authors: Sorokina E. , Akhmatova E. , Sentsova E.
Published: May 2024

Objective. To study the efficacy of Blue Cap emollient in patients with psoriasis. Material and methods. The study included 10 patients with psoriasis vulgaris, limited form, stationary stage. Patients were divided into 2 groups: 1st (n=5) – patients received basic therapy (betamethasone + calcipotriol ointment once a day for 2 weeks) against the background of emollient application (containing piroctonolamine, bisabolol, ceramides, cholesterol, phytosphingosine, glycerol, glyceryl stearate); 2nd (n=5) - patients received only basic therapy. The severity of the course of psoriasis and the effectiveness of therapy according to clinical signs were assessed using the Psoriasis Area and Severity Index (PASI). The severity of pruritus and the impact of pruritus on patients' quality of life were assessed using the Behavioral rating scores (BRS) questionnaire and the pruritus index “Prurindex”. Results. Inclusion of Blue Cap emollient into the treatment protocol of psoriasis patients against the background of basic therapy (betamethasone + calcipotriol) promoted a significant decrease in PASI and improvement of skin condition in comparison with the group receiving only basic therapy.
Trajerória de uma personagem negra sob o prisma do mito da meritocracia racial presente em nossa sociedade
Authors: Pereira Josineide Barbosa , Rodrigues Jannabsa Jussara , Santos Josilene de França , Mamedes Rosilene Felix
Published: May 2024

A proposta deste ensaio é acompanhar a trajetória de uma personagem negra que sai de uma escola da periferia de São Paulo para estudar em uma escola conceituada no grande centro, através de uma bolsa de estudos que foi conquistada por mérito próprio e sob essa ótica, a do merecimento que pauto minha pesquisa, nossa perssonagem central ao longo da narrativa vai construindo e ressignificando sua identidade, buscando sempre a sua ancestralidade como pedra fundamental. Ao longo dessa jornada de preconceitos e conceitos amplamente divuldados em nossa sociedade. Uma história ficcional escrita por autoras femininas e negras, mas que tráz em sua narrativa longos anos de pesquisa como profissionais da educação, mas também de vivências que como mulheres pretas nesse país tão preconceituoso e cruel sentem na pele todos os dias o peso da naturalização de falas problemáticas que tem como intuito colocar a população negra no seu lugar, ou seja enquadrar essas pessoas em um espaço que foi definido a muito tempo por um grupo social que tem em seu escopo pessoas brancas. Através da trajetória de Mira espero desenhar um quadro de lutas ainda enfrentados todos os dias em nossa sociedade, mas que encontra na escola um espaço de referência para resistência, conscientização e humanização das relações étnico-raciais no Brasil.
PODER E REPRESSÃO E SUA INTER-RELAÇÃO COM O ESPAÇO LITERÁRIO DE OS QUE BEBEM COMO OS CÃES, DE ASSIS BRASIL
Authors: Carvalho Ederson Dias de
Published: May 2024

O objetivo da presente pesquisa é apresentar o espaço literário da obra Os que bebem como os cães, do escritor piauiense Assis Brasil, sob a ótica da relação entre poder e repressão. Na esteira de conceitos topoanalíticos, tais como fronteira e topopatia, o espaço ficcional da referida obra é desnudado. Com isso, situações de horror e sofrimento são reveladas, com personagens vivendo em meio a situações sub-humanas no presídio. Desse modo, nota-se que o espaço oferece elementos para que os leitores possam refletir acerca das condições de poder e repressão presentes no referido texto do citado escritor. Tem-se aqui uma pesquisa bibliográfica, de cunho analítico-qualitativa, que utiliza como aporte teórico os seguintes escritores: Borges Filho (2007), Bourdieu (2007), Foucault (2013), dentre outros. Os resultados demonstram que analisar uma obra literária, com base em conceitos topoanalíticos, ajuda o leitor a compreender, de forma holística e crítica, perspectivas outras acerca do espaço ficcional nela contido.
ORNAMENTOS E FANTASMAGORIAS: O GÓTICO E A TEATRALIZAÇÃO DA HISTÓRIA
Authors: Colucci Fernando Monteiro de Barros; Luciana
Published: May 2024

O Gótico surgiu e tem permanecido uma estética, um gênero, um modo, definitivamente assombrado pelo peso da História. A partir desse entendimento, pretendemos demonstrar de que maneira a conjunção entre a vertente literária goticista e a categoria espaço - a partir da figura do castelo com seus mobiliários, objetos, ornamentos, jóias - estabelece uma visão desencantada do mundo inaugurada pela modernidade iluminista.
ALÉM DA VIDA E DA MORTE: HISTÓRIAS DE FANTASMA E O ESPAÇO ASSOMBRADO
Authors: Gonçalves Alanis Zambrini
Published: May 2024

Este artigo busca estudar a fascinação com o sobrenatural na Era Vitoriana, principalmente ao considerar a literatura sobre fantasmas que circulava na época, tomando como exemplo os contos The Old Nurse's Story, de Elizabeth Gaskell e The Ghost in the Bride's Chamber, de Charles Dickens, bem como a novela The Turn of the Screw, de Henry James. A partir disso, busca-se definir as três obras em relação ao chamado Gótico Vitoriano, pensando no conceito de gótico que abrangeria este período e suas especificidades. Além disso, considera-se a importância do terror e do espaço em meio a esse tipo de literatura gótica, sobretudo ao pensar-se sobre o ambiente da casa assombrada. Por fim, busca-se considerar a possível influência de outros campos nas histórias de fantasma, bem como no Gótico Vitoriano, como é o caso do espiritismo.
REPRESENTAÇÕES DO ESPAÇO NO LIVRO POP-UP: PROPOSTAS DE FRUIÇÃO
Authors: Macedo Márcia , Melão Dulce , Menezes Luís
Published: May 2024

Neste artigo procura-se articular a literatura para a infância com a matemática por meio do livro-objeto, em formato pop-up, Oh! O meu chapéu (BOISROBERT & RIGAUD, 2015), desvelando a importância do caráter plurissignificativo dos espaços que aí se desdobram. Foram traçados os seguintes objetivos: i) indagar modos de apurar a sensibilidade estética das crianças, através da exploração sensorial e espacial do livro pop-up, com particular ênfase nos elementos paratextuais; ii) compreender as potencialidades dos espaços redesenhados no livro em análise, para o incremento da criatividade e imaginação, através da exploração da simbiose entre o texto e as ilustrações, locus de articulação da literatura com a matemática. Conclui-se que o caráter tridimensional do livro pop-up possibilita a criação de pactos de leitura inusitados, revelando o seu potencial invulgar de fruição, ainda pouco explorado.
PRELIMINARES DE UM ESTUDO SOBRE A ESPACIALIDADE EM BERLIN ALEXANDERPLATZ, DE ALFRED DÖBLIN
Authors: Vespasiano Rafael
Published: May 2024

Este artigo pretende apresentar um estudo, a respeito de como certos aspectos espaciais são desenvolvidos na obra literária Berlin Alexanderplatz (1929) de Alfred Döblin. Deseja-se evidenciar a importância do espaço da praça Alexanderplatz, como sendo um espaço privilegiado para o desenvolvimento da narrativa e para a composição das personagens do romance. Levando em conta que o autor pensa seu romance como uma obra épica moderna. O que leva a compreender também que se trata de um romance que evidencia a crise do romance enquanto gênero. Além de demonstrar que a obra é um romance moderno e vanguardista em sua feitura. Dessa maneira, espera-se evidenciar a relevância da praça como um espaço fulcral na elaboração e no desenvolvimento, não só da narrativa, mas também na composição das personagens, que transitam e habitam a Alexanderplatz, naquele período tão importante para a história da sociedade alemã.
RELATO DE EXPERIÊNCIA DE INTOLERÂNCIA ACOMETIDA CONTRA CRIANÇA PORTADORA DE TEA (TRANSTORNO DE ESPECTRO AUTISTA)
Authors: Andrade Mariseth Carvalho de , Silva Jofre Jacob da
Published: May 2024

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Carrageenan-amino acid interaction as a tool for understanding atherosclerotic process initiation
Authors: Chiconi de Picoli Paula Monique , Araújo Soares Tatiane , Marques Gonçalves Adriano , Trovatti Eliane
Published: May 2024

Atherosclerosis is the primary trigger for severe pathologies. The atherosclerotic inflammatory process is well known after low-density lipoprotein (LDL) adhesion in blood vessel walls, however, limited information exists regarding LDL penetration into subendothelial layers. Here, we propose for the first time, to the best of our knowledge, the pathway for the initial trajectory of the lipid molecules internalization into the arterial endothelial tissue. The investigation shows a computational model analyzing molecules involved in the atherosclerotic process, specifically LDL and molecules of the vascular endothelium. The theoretical model was experimentally tested using carrageenan to simulate the anionic counterparts of vascular tissue and amino acids from apolipoprotein B-100. The molecular interactions were analyzed by conductimetric titration, FTIR, and rheology. The computational model identified potential amino acids involved in the process, and the experimental results demonstrated the interaction between lysine and polymer, as the mechanism of adhesion, confirming the model.
What's in a Name? The Evolution of a Feminist Researcher
Authors: Reinharz Shulamit
Published: May 2024

Abstract: This essay offers the story of my nearly fifty-year career as a sociologist, through the lens of feminist ideas and my relationships with some women and men. It traces my learning of feminist concepts both as abstract ideas and as lived experiences in two universities. This overview is constructed on two lines of inquiry—the passage of time and the concept of names. It also includes discussion of power dynamics in Women's Studies Programs; the integration of pregnancy, miscarriage, and childbirth into a woman's career; and other phenomena that many women experience. It concludes with two illustrations of the significance of women's names, in Israeli communities and in the Bible. This last section suggests the vast array of ways in which we can bring women to the forefront even when individual women abandon the concept of sisterhood.
THE USE OF ARTIFICIAL INTELLIGENCE IN DEVELOPING AUTOGENIC TRAINING FOR PSYCHOPHYSIOLOGICAL STATE CORRECTION IN HIGH-RISK PROFESSIONALS TO PREVENT FUNCTIONAL IMPAIRMENTS
Authors: Rode Anna , Rode Yulia
Published: May 2024

The aim of the article is to assess the potential for implementing AI tools in the development of autogenic training programs aimed at correcting the psychophysical state of high-risk professionals prone to disorders leading to functional impairments. Research findings indicate that high-risk professions are associated with stress, high demands, and hazards that contribute to the development of psychophysical disorders, such as burnout and emotional exhaustion. Autogenic training is an effective self-regulation method that reduces stress and enhances overall well-being, becoming a key element in the prevention of burnout and emotional exhaustion. AI can be utilized to create personalized applications that provide interactive effects for sensations of warmth and heaviness, recording and playback of personalized affirmations, audio-visual effects to create a sensation of coolness, audio guides for the sensation of gravity, tools for deep relaxation, and musical accompaniments for music therapy.