bluuebunny/crossref_metadata_2025 huggingface dataset:
Breast Screen Service Characteristics as a Measure of Accessibility
Authors: Gaans Deborah Van , Coffee Neil , Daniel Mark , Roder David
Published: November 2018

Breast Screen Australia is a national breast cancer screening program which aims to reduce illness and death from breast cancer through early detection using mammography. Through this program women aged 40 and over in Australia are eligible for a free mammogram every two years. Around 55% of the target population participate in the program. Understanding the accessibility of breast screen services has the potential to improve the uptake of screening services. Spatial analysis of individual breast screen services: opening hours, disability and accessibility infrastructure, parking and transport data can be used to describe the accessibility of breast screen services. Through highlighting regional accessibility to breast screen services it is possible to identify regions where accessibility to services could be increased to improved equity in health service provision.
Correlation Comparisons of Early and Aged Quality Traits of Pork Aged Either as Intact Loins or Case-Ready Chops
Authors: Klehm B. J. , Overholt M. F. , Lowell J. E. , King D. A. , Shackelford S. D. , Dilger A. C. , Boler D. D.
Published: November 2018

Approximately half of retail pork chops in the U.S. arrive at the store in case-ready packages. The other half arrives as intact-loins and are sliced when needed. Cutting chops from loins may increase moisture loss leading to lighter colored and less juicy meat. Therefore, it is possible that correlations between loin quality traits observed early postmortem (PM) and aged quality traits would differ between intact-loin aged (ILA) chops and case-ready aged (CRA) chops. Loins (288 total) were selected to fill a matrix that varied in visual color and marbling. Loins were assigned to 1 of 2 packaging treatments (n = 144): ILA or CRA. Loins assigned as ILA remained vacuum-packaged at 4°C until 12 d PM, sliced and chop surface was evaluated. Loins assigned to CRA were sliced into 28-mm thick chops at 2 d PM, packaged in individual Styrofoam trays overwrapped in polyvinyl-chloride (PVC) film, and gas flushed in bulk packages. Quality parameters of packaging treatments at early and aged time points were compared as a randomized complete block design. Pearson correlation coefficients between early and aged quality traits for packaging treatments were transformed using Fisher’s r to z transformation for independent correlation comparisons of packaging treatments. Chops from ILA were darker and redder at 12 d PM than CRA chops (P < 0.0001). Lightness and redness values on ventral surface for ILA loins (r = 0.52 lightness; r = 0.63 redness) and CRA loins (r = 0.45 lightness; r = 0.61 redness) at 1 d PM were both correlated with aged lightness and redness values on aged chop face at 12 d PM and the correlations did not differ (P ≥ 0.43) for either trait. Overall, aging intact loins in vacuum-packaging improved color after 12 d of aging compared with aging chops in case-ready packaging. Despite the differences between aging methods, the correlations between early and aged loin quality didn’t differ.
Evaluación del impacto del cambio climático sobre una cuenca hidrológica en régimen natural (SE, España) usando un modelo SWAT
Authors: Jodar-Abellan Antonio , Ruiz Marcos , Melgarejo Joaquin
Published: November 2018

Actualmente, las demandas hídricas se encuentran en continuo crecimiento lo que aumenta la presión, en cantidad y calidad, sobre los recursos hídricos disponibles a nivel global. Asimismo, la reducción proyectada de las aportaciones en régimen natural, consecuencia del cambio climático, supone un nuevo nivel de incertidumbre. Pese a errores todavía existentes, los modelos hidrológicos constituyen herramientas vitales para planificar y gestionar el recurso agua. Su correcta aplicación resulta esencial en áreas con elevado estrés hídrico (regiones áridas y semiáridas). La Demarcación Hidrográfica del Segura (DHS), sureste de España, presenta una de las mayores tasas de escasez y explotación intensiva de recursos hídricos en el contexto europeo y mundial. Este trabajo estima los efectos del cambio climático sobre los principales componentes del balance hídrico en la cuenca alta del río Taibilla (cabecera de la DHS). Dicha cuenca fue escogida al encontrase en régimen natural y ser actualmente primordial en el abastecimiento hídrico de numerosos municipios de la DHS y áreas contiguas. Para evaluar los mencionados efectos se ha implementado el modelo Soil and Water Assessment Tool (SWAT) calibrado con el algoritmo SUFI-2. La calibración y validación se realizaron con dos funciones objetivo (NSE y KGE) en el periodo con caudales observados (1996-2012). Las proyecciones de precipitación y temperatura proceden de los modelos climáticos globales (GCMs) bcc-csm1-1-m, MPI.ESM.MR y bcc.csm1.1, regionalizados con la técnica de Análogos, bajo los escenarios de emisión RCP4.5 y RCP8.5 (periodo 2010-2050). Los resultados del ajuste mejoran con NSE, con respecto a KGE, en las series de calibración y validación. En las próximas décadas, precipitación, escorrentía superficial y recarga de acuíferos muestran tendencias negativas mientras que la temperatura aumenta entre 1.5 °C y 1.7 °C. Pese a la incertidumbre existente, resulta evidente que las aportaciones disminuirán en la cuenca lo que supondrá un reto en la gestión del recurso agua para las autoridades locales. Los resultados obtenidos pueden ayudar a las autoridades locales en la toma de decisiones respecto a la planificación hidrológica y la lucha contra el cambio climático en la DHS. Así mismo, SWAT como herramienta de conversión lluvia-escorrentía, junto con los modelos y escenarios de cambio climático implementados, resultan válidos en un área de clima subhúmedo y semiárido pudiendo ser aplicados en otras regiones con una climatología similar.
MMOG/LE: Improving supply chain delivery performance through buyer- supplier collaboration
Authors: Butler Timothy W , Williams David L , Yan Tingting
Published: November 2018

This article introduces readers to a relatively new self-assessment tool for measuring the readiness and effectiveness of supplier materials management and logistics processes in the automotive industry. The tool, the Material Management Operating Guidelines/Logistics Evaluation (MMOG/ LE), was developed by the Automotive Industry Action Group (AIAG), and Odette International – a European alliance of automotive companies. The article begins with an introduction to the topic of quality and materials management assessment systems. The author’s then report on what they learned about MMOG/LE based on a review of the system and other comparable systems, and based on interviews with OEM’s and tier 1 and 2 auto suppliers that use the system. The article begins with a description of what the MMOG/LE system is, and how it works. The article then has a section comparing MMOG/LE and ISO/TS16949, and then another section comparing MMOG/LE and the SCOR model. The authors then address and comment on various strengths and weaknesses of the MMOG/LE model. Finally, the authors make several recommendations on how the system and processes for managing it could be improved. Overall, the authors find that MMOG/LE is an effective system for improving materials management and logistics performance.
Nasab Anak yang Lahir di luar Nikah: Analisis Fatwa MPU Aceh Nomor 18 Tahun 2015 dan Keputusan MK Nomor 46/PUU/-VIII/2010
Authors: Nasaiy Aziz Nasaiy Aziz , Muksal Mina Muksal Mina
Published: November 2018

Status hukum anak luar nikah masih beragam. Mahkamah Konstitusi telah menetapkan adanya hubungan status keperdataan anak dengan ayah biologisnya. Sementara itu, MPU Aceh juga telah mengeluarkan fatwa yang sebaliknya dengan Putusan MK. Masalah yang diteliti adalah bagaimana status hukum anak luar nikah dilihat dari berbagai perspektif, bagaimana pertimbangan Hakim Mahkamah Konstitusi dalam keputusan Nomor 46/PUU/-VIII/2010 terkait dengan penentuan status keperdataan anak luar nikah dan bagaimana tinjauan fatwa MPU Aceh No 18 Tahun 2015 tentang nasab anak yang lahir diluar nikah (anak zina) terhadap putusan Mahkamah Konstitusi Nomor 46/PUU-VIII/2010 tentang nasab anak yang lahir diluar nikah. Untuk menjawab permasalahan tersebut, penulis menggunakan studi kepustakaan (library research) dan dilakukan dengan menggunakan metode deskriptif-analisis. Hasil analisa penulis menunjukkan bahwa dalam hukum Islam, nasab anak terputus dengan laki-laki pezina, begitu juga yang dimuat dalam Undang-Undang Perkawinan. Adapun pertimbangan Hakim MK adalah dengan pertimbangan kemaslahatan dan perlindungan anak. Adapun tinjauan fatwa MPU Aceh terhadap putusan MK yaitu ada dua. Pertama, menetapkan terputusnya nasab anak pada laki-laki pezina yang sebelumnya MK tetap menetapkannya. Kedua, Mahkamah Konstitusi menganggap deskriminasi terkait dengan pemutusan hubungan perdata anak luar nikah dengan ayah biologis, sedangkan MPU Aceh meninjau bahwa pemutusan hubungan nasab dan keperdataan anak dengan laki-laki zina dan menisbatkannya kepada ibu dan keluarga ibu anak, sebagai bentuk perlindungan nasab, bukan sebagai bentuk deskriminasi.
Problematika Penyelesaian Perkara Kumulasi Gugatan Perceraian dan Harta Bersama (Studi Kasus di Mahkamah Syarâ€™iyah Banda Aceh)
Authors: Daud Mohd Kalam , Saputra Ridha
Published: November 2018

Kumulasi gugatan (samenvoeging van vordering) bertujuan untuk menyerderhanakan proses persidangan dan menghindari putusan yang bertentangan. Akan tetapi dalam prakteknya, penggabungan kedua perkara ini di Mahkamah Syarâ€™iyah Banda Aceh justru membuat penyelesaiannya menjadi berlarut-larut dan memakan waktu lama. Penelitian ini membahas tentang penyelesaian perkara kumulasi gugatan perceraian dan harta bersama di Mahkamah Syarâ€™iyah Banda Aceh, problematika yang dihadapi hakim Mahkamah Syarâ€™iyah Banda Aceh dalam penyelesaian perkara kumulasi ini, dan bagaimana tinjauan hukum Islam terhadap penyelesaian perkara kumulasi tersebut. Penelitian dalam artikel ini menggunakan pendekatan yuridis empiris dan menggunakan metode pengumpulan data lapangan yang dipadukan dengan metode pengumpulan data kepustakaan melalui teknik wawancara dan dokumentasi.Setelah dilakukan penelitian ditemukan hasil bahwa penyelesaian perkara kumulasi gugatan perceraian dan harta bersama di Mahkamah Syarâ€™iyah Banda Aceh dilakukan dengan tahapan perdamaian, mediasi, pemeriksaan terhadap gugatan cerai dalam sidang yang tertutup untuk umum, pemeriksaan terhadap gugatan pembagian harta bersama dalam sidang yang terbuka untuk umum, musyawarah majelis hakim, dan pembacaan putusan. Adapun problematika yang dihadapi hakim dalam proses penyelesaian perkara kumulasi ini adalah adanya perbedaan praktek dalam tata cara penyelesaian perkara kumulasi ini, waktu penyelesaian perkara yang relatif lama, proses pembuktian terhadap objek perkara harta bersama yang sulit, dan seringkali objek yang dipersengketakan dijual oleh tergugat. Ada 3 (tiga) metode penemuan hukum (istinbaá¹­) yang bisa menjadi landasan hakim Mahkamah Syarâ€™iyah Banda Aceh sebagai cara alternatif untuk menyelesaikan perkara kumulasi perceraian dan harta bersama, yaitu: metode analogi (qiyÄs), metode barÄâ€™ah al- aá¹£liyyah, dan metode maá¹£laá¸¥ah al-mursalah.
Copycat Fast Casual Restaurants: Consumer Response of Dublin Professionals 25 - 39
Authors: Brewer Audrey
Published: November 2018

The fast casual market in Ireland is growing at a rate three times that of other restaurant categories. It is especially popular with young professionals aged 25-39, representing more than one third of their food spend. Many Dublin restaurateurs have taken this opportunity to capitalise on the success of existing restaurant brands and open “copycat” eateries within the capital. These restaurants appropriate concepts, menus and trade dress from leader brands outside Ireland, often to commercial success. By using a mixed quantitative and qualitative approach, this research aims to explore Irish consumer perception and patronage of five Dublin copycat restaurants and negotiate the results of this with consumers’ evaluation of authenticity. Two hundred and twenty-seven questionnaire responses were evaluated and phenomenologically assessed through in-depth interviews to try to explain the socioeconomic and cultural factors of these results. Findings indicate a generally positive acceptance towards copycatting in Ireland, while still evaluating the “original” restaurant as better in most categories. In this context, a moderate similarity approach appears to work best when the leader brand is not present. Respondents did not have an overall negative view of copycats, and even fewer reported a desire to stop visiting such restaurants once informed about them. Interviews investigated the regulatory, economic and cultural underpinnings for this, suggesting consumer response is dictated by contextual factors that are unique to the Irish commercial landscape.
SMN1 copy number as a modifying factor of survival in Serbian patients with sporadic amyotrophic lateral sclerosis
Authors: Brkusanin Milos , Jeftovic-Velkova Irena , Jovanovic Vladimir , Peric Stojan , Pesovic Jovan , Brajuskovic Goran , Stevic Zorica , Savic-Pavicevic Dusanka
Published: November 2018

Introduction/Objective. Amyotrophic lateral sclerosis (ALS) is a devastating motor neuron disease. The majority of cases are apparently sporadic ALS (SALS) with variants in susceptibility genes or sometimes in high-risk ALS genes. Two ALS susceptibility genes are SMN1, whose functional loss causes spinal muscular atrophy (SMA), and a nearly identical SMN2 gene, which modulates SMA severity. In this study we examined the association of copy number variations (CNVs) of SMN1 and SMN2 genes and two additional genes, SERF1 and NAIP, residing in the same genomic region (i.e. 5q13.2 segmental duplication), with SALS in patients from Serbia. Methods. Multiplex ligation-dependent probe amplification was used to determine CNVs of each gene in a clinically well-characterised group of 153 Serbian SALS patients and 153 controls. Results. Individual association between SMN1, SMN2, SERF1 or NAIP CNVs and SALS susceptibility or survival was not found. Survival curves based on the multivariable Cox regression analysis showed that three SMN1 copies, lower ALS Functional Rating Scale Revised (ALSFRS-R) score at the time of diagnosis, faster decline of the ALSFRS-R score over time, and shorter diagnostic delay result in shorter survival of Serbian SALS patients. Conclusion. Clinical variables might be complemented with the SMN1 copy number to improve prediction of survival in Serbian SALS patients.
Real-World Database Examining the Association Between Avascular Necrosis of the Femoral Head and Diabetes in Taiwan
Authors: Lai Shih-Wei , Lin Cheng-Li , Liao Kuan-Fu
Published: November 2018

OBJECTIVE

No study has been conducted to evaluate the association between avascular necrosis of the femoral head and diabetes. This study’s aim was to assess this issue in Taiwan.

RESEARCH DESIGN AND METHODS

A population-based cohort study was performed to analyze the database of Taiwan’s National Health Insurance Program. There were 27,869 subjects aged 20–84 years with newly diagnosed diabetes from 2000 to 2012 as the group with diabetes. The group without diabetes included 111,476 sex- and age-matched subjects without diabetes. The incidence of avascular necrosis of the femoral head at the end of 2013 was measured. A multivariable Cox proportional hazards regression model was used to measure the hazard ratio (HR) and 95% CI for avascular necrosis of the femoral head associated with diabetes.

RESULTS

The overall incidence of avascular necrosis of the femoral head was 1.37-fold higher in the group with diabetes than in the group without diabetes (6.53 vs. 4.76 per 1,000 person-years [95% CI 1.31–1.43]). After adjusting for confounders, the HR of avascular necrosis of the femoral head was 1.16 (95% CI 1.11–1.21) for the subjects with diabetes compared with the subjects without diabetes.

CONCLUSIONS

Patients with diabetes have a 1.16-fold increased risk for developing avascular necrosis of the femoral head.
Visión artificial mediante el coeficiente de correlación para exámenes de retinoscopía
Authors: Vallejo Vizhuete Henry Ernesto , Paucar Jorge , Martinez Oswaldo
Published: November 2018

Se diseñó e implementó un sistema automatizado para realizar exámenes de retinoscopía empleando visión artificial con el coeficiente de correlación para el procesamiento de imágenes de la retina. Se empleó la técnica de observación y experimentación, para identificar las condiciones necesarias que intervienen en la realización del examen de retinoscopía, se estableció un diseño del sistema mecánico, electrónico y de visión artificial para la selección e instalación de los componentes requeridos para la automatización. Para el funcionamiento del sistema automatizado se desarrolló un algoritmo de procesamiento y comparación de imágenes programadas en el software LabVIEW; a través de una conexión con el puerto serial se envía datos desde el computador hacia la tarjeta de desarrollo Arduino Uno la cual controla los actuadores que son servomotores que direccionan la posición de los lentes y efectúan el movimiento del haz de luz del retinoscopio. Para el cambio automático de lentes se implementó un sistema mecánico para obtener una imagen fija de la retina; se creó una interfaz hombre máquina (HMI), que permite al operador visualizar el proceso del examen en tiempo real. Se determinó el tiempo promedio de la comparación de imágenes, resultando que: ojos sin ametropía se comparan en 162,28 ms, con miopía en 166,02 ms, con hipermetropía en 170,7 ms y con astigmatismo en 174,75 ms, logrando reducir el tiempo promedio empleado para realizar el examen de retinoscopía de 250 a 150 segundos equivalente al 40%. Se concluyó que el tiempo de comparación de las imágenes incrementa en 2,44% mientras mayor sea el daño refractivo.
IDENTIFICATION AND ANALYSIS OF WEED VEGETATION AS Ganoderma PRESENCE MARKER ON OIL PALM PLANTATION
Authors: Saragih Wismaroh Sanniwati , Purba Edison , Tampubolon Koko
Published: November 2018

Weeds on oil palm plantations can also be the host of Basal Stem Rot caused by Ganoderma. This study aims to identify and analyze of weed vegetation using visual estimation and squares method as Ganoderma presence marker on oil palm plantations. This research was conducted in block 17, 16, and 6 of VII afdeling, Rambutan Estate in Serdang Bedagai Regency on December 2017 to March 2018. This research used survey method with visual estimation and squares. The data used is absolute density, relative density, absolute frequency, relative frequency, important value indeks, Summed Dominance Ratio (SDR) and dry weight. Data analysis using IBM SPSS Statistics 20 software. The results showed that different weed species between oil palm was infected and uninfected by Ganoderma with visual estimation method is Cyclosorus aridus (14.78%) where as with squares method are Cyperus rotundus (10.60%), and Stenochlaena palustris (7.76%) with temperature range 28.67 to 30.80oC and moisture amount 60.67 to 77.33%.
A PRELIMINARY STUDY ON AQUIFER IDENTIFICATION BASED ON GEO-ELECTRICAL DATA IN BANDA ACEH, INDONESIA
Authors: Sugiyanto Didik , Rusydy Ibnu , Marwan Marwan , Hidayati Dian Mutia , Asrillah Asrillah
Published: November 2018

The aquifers exploration has been conducted at the western part of Banda Aceh, Indonesia. This research aims to explore the aquifer layer beneath the surface and to obtain the cross-section model of the aquifer. The Vertical Electrical Sounding (VES) method was applied to investigate the aquifer layer. The VES method worked as the current penetrated into the ground using of two electrodes and the potential response due to its current being measured by another two electrodes. Ten grid points of VES has performed in western part of Krueng Aceh of Banda Aceh using the ARES (Automatic Resistivity Meter). The Res1Dinv and curve matching computer software used in VES data processing and analysis. The result shows the resistivity value of aquifer in Banda Aceh city at the range of 1 – 12 Ωm for freshwater, and 0.1 – 0.6 for brackish water layer. The first aquifer (water table) found at a depth of 0.5 to 2 meters beneath the surface. The 2-meters water table mostly located near the coastal zone or downstream zone of Krueng Aceh basin and shallow depth of 0.5 meters on the upstream. More than one aquifer layers were found beneath the surface, they were separated by aquitard layer consisting of silt to clay layers.
ANALYSIS OF SHALLOW SUBSURFACE AT HYDROCARBON POTENTIAL AREAS IN NORTH ACEH BASED ON ELECTRICAL RESISTIVITY MODEL
Authors: Aflah Nurul , Muchlis Muchlis , Idris Syafrizal , Ardjakusumah Witan O
Published: November 2018

Hydrocarbon prospect area research has been done in North Aceh at two locations. The research aims to analyze subsurface litology using  resistivity method. Data acquisition of each location was presented by 330 m line survey. The acquisition process was generated by Super Sting R8/IP and modelled by EarthImager 2D. Oil and gas (NA1) resistivity section showed anomaly at 170 m (x) and 17 m (z) that was identified as minor fault. However, oil seepage was not founded on the location. Fossil locality (NA2) section showed a contrast vertical anomaly (16-90 Ωm) around 90 – 120 m that was identified as a way for the seepage.
Lenkung und Ablenkung - Zu den Regiebemerkungen bei John von Düffel, Peter Handke und Franz Xaver Kroetz
Authors: Honegger Serge Brian
Published: November 2018

Sprache und Schrift steuern Handlungen und Wahrnehmungen von Adressaten. Dabei praktizieren Texte eine Führungsmodalität, die sich im Spannungsfeld von ‹Vorschreiben› und ‹Offenlassen› bewegt. Den Gegenstand der Publikation bilden vier Theaterstücke ohne Figurenreden von John von Düffel, Peter Handke und Franz Xaver Kroetz. Im Textraum der Regiebemerkungen reflektieren die Autoren die entmaterialisierenden Wirkungen in Bezug auf die Transformation des literarischen Textes ins Aufführungsmedium. Sie machen auf den Status des Schriftlichen　im Umfeld von Regietheater und beginnendem digitalen Zeitalter aufmerksam.　
Allesamt in der zweiten Hälfte des 20. Jahrhunderts entstanden, lässt sich an den Dramentexten ein verändertes Verständnis von Führung und ‹Leadership› ablesen. Dieses verabschiedet sich von hierarchisch strukturierten Organisationsprinzipien sowie determinierenden Planbarkeits- und Kontrollvorstellungen.
DAMPAK URBANISASI BAGI PEMBANGUNAN MANUSIA 2010-2016 Studi Kasus: Jakarta, Surabaya dan Medan
Authors: Prasodjo Iwan
Published: November 2018

This article discusses the effect of urbanization on Human Development Index during 2010-16. It shows that Jakarta has the highest population growth and Gross Domestic Regional Product. However, Surabaya has the highest Human Development Index. Eventhough,  Jakarta, with the highest  Gross Domestic Regional Product,  does not indicate the highest Human Development Index. On the other hand, Medan has the lowest Gross Domestic Regional Product.  Not only Medan has  the lowest  Gross Domestic Regional Product, but also it has the lowest Human Development Index.
A NOVEL APPROACH OF ARTESUNATE PELLETS FOR THE TREATMENT OF MALARIA
Authors: Shabaraya A. R. , Parulkar Ankit S , Kamath Krishnananda K , Shripathy D
Published: November 2018

Tropical countries such as India are more prone to the malaria and around 2 million cases are reported annually. Malaria is one of the most prominent life threatening diseases in spite of many efforts made to fight against it. There are many clinically effective anti-malarial agents but the major reasons of malaria treatment failure are due to resistance development, incorrect dosing, poor drug quality, drug interactions, poor drug absorption and misdiagnosis. Current approach done in this study is to formulate a dosage form which can overcome these drawbacks. Here pellets of Artesunate were formulated by extrusion spheronization method using different concentration of ethyl cellulose and evaluated for preformulation studies, drug compatibility studies were carried out. Formulations were evaluated for particles size analysis, zeta potential and in-vitro dissolution studies. The pellets were obtained in the size range of 10 – 100µm. The evaluation results obtained showed that the formulation F4 having high concentration of ethyl cellulose showed the best release profile.
La cultura en Veracruz
Authors: La Palabra y el Hombre Redacción
Published: November 2018

"En un contexto de cambios históricos en nuestro país, La Palabra y el Hombre, en coordinación con el Cuerpo Académico Estudios Literarios Mexicanos. Siglos XX y XXI, de la Facultad de Letras Españolas, ofrece a sus lectores un número especial dedicado a diferentes voces y manifestaciones artísticas en Veracruz. El objetivo primordial es mostrar un mosaico, si no completo, sí representativo del cruce generacional de creadores e investigadores en el estado, sin por ello caer en equívocos regionalismos ni exaltaciones localistas".
La fuga
Authors: Pineda Melgarejo Brianda
Published: November 2018

Brianda Pineda Melgarejo estudió Lengua y Literatura Hispánicas en la UV. Ha publicado en La Palabra y el Hombre, F.I.L.M.E y Liberoamérica (traducciones y ensayo). Participó en el área de poesía en la XIV generación de la FLM.
Bestias Negras
Authors: Fund Sebastian
Published: November 2018

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Nuestras artistas de páginas interiores
Authors: De páginas interiores Nuestras artistas
Published: November 2018

Atenea C.B  es pintora e ilustradora egresada de la Facultad de Artes Plásticas de la Universidad Veracruzana. En 2016 ganó el premio de selección de la Tercera Bienal de Arte en Veracruz. Ha participado en alrededor de quince exposiciones colectivas y cinco individuales, la más reciente: Unus Mundus. En 2014 fue beneficiaria del Programa de Estímulos a la Creación y Desarrollo Artístico en Veracruz.Paulina Vilchis ha sido acreedora de la beca Jóvenes Creadores otorgada por el Ivec. Su técnica consiste en trabajar el grabado para intervenirlo después con otros materiales como el collage y la acuarela.
SOSIALISASI DAN PELATIHAN PEMANFAATAN BIOGAS DARI KOTORAN TERNAK DAN JERAMI PADI SEBAGAI SUMBER ENERGI ALTERNATIF RAMAH LINGKUNGAN
Authors: Irsyad Fadli , Yanti Delvi , Andasuryani Andasuryani
Published: November 2018

Kegiatan ini bertujuan untuk mentransfer pengetahuan dan teknologi pemanfaatan kotoran ternak dan jerami padi sebagai sumber energi alternatif ramah lingkungan berupa biogas. Dari kegiatan ini, diharapkan petani mendapatkan manfaat sosial dan ekonomis dari limbah yang dihasilkannya sendiri. Metode yang digunakan dalam pelaksanaan kegiatan ini adalah ceramah, demonstrasi, dan eksperimen. Hasil kegiatan sosialisasi dan pelatihan pemanfaatan biogas dari kotoran ternak dan jerami padi dapat mencapai sasaran sesuai dengan tujuan kegiatan pengabdian masyarakat, hal ini dapat dilihat dari peningkatan pemahaman peserta terhadap pengolahan limbah menjadi biogas setelah kegiatan sebesar 50%.
Cesarean scar defect- obstetric consequences
Authors: Balalau Oana D. , Corbu Teodora A. , Ples Liana , Dumitru Vasile A. , Stanescu Anca D.
Published: November 2018

Scope. This review aims to achieve a parallelism between literature studies on imaging diagnosis, the characteristics of cesarean scar defect and its evolution during pregnancy, and the obstetric consequences that can lead to increased maternal morbidity. Materials and Methods. There have been many literature studies published in recent years aimed to identify the methods of diagnosis for cesarean scar defect, the characteristics and the main changes of it during pregnancy, and the risks undertaken by pregnant women undergoing labor for vaginal delivery after a previous cesarean surgery. Results and Discussions. The most commonly used method for visualizing and evaluating uterine scar is transvaginal ultrasound in the first trimester of pregnancy, and abdominal ultrasonography in the II and III trimesters. The two areas characteristic of uterine scarring: "niche" and "thickness of the residual myometrium" undergo changes during the three trimesters of pregnancy. Some studies in the literature reported a higher incidence of uterine rupture, especially when the lower uterine segment fell below 2.3 mm, and a mean thickness of 3.2 mm, higher among multiparous women. A question that still does not have a generally valid answer refers to the hysterorrhaphy technique. There are different opinions among the authors, but most of them consider that after a double layer suture the thickness of the residual myometrium is higher. However, data from the literature show that the incidence of complications such as uterine rupture, dehiscence of the uterine trance are similar, regardless of the type of suture used. Another complication that occurs due to uterine scar is the pregnancy inserted at this level, which in the case of expectancy, leads to an increase in maternal and fetal morbidity. 50% of them evolve to spontaneous abortion in the first trimester, and almost all full-term pregnancies result in hysterectomy of necessity. Conclusions. Due to the many obstetrical and gynecological complications that occur on a uterine scar, an evaluation in dynamics is essential. There are no standardized protocols yet, but the identification and measurement of the uterine scar area in the third trimester may predict the chance of success of the labor test for vaginal delivery after cesarean surgery.
Larynx stenosis; a challenge for the ENT surgeons
Authors: Bertesteanu Șerban V. , Pascu Paula , Popescu Cristian , Grigore Raluca , Popescu Bogdan
Published: November 2018

Laryngo-tracheal stenosis is a complex pathology which requires multiple surgical interventions and diligence from the surgeon and patience from the patient so that normal physiology may be restored. The aim of this paper is to evaluate the factors that can influence the evolution of this pathology. It is presented a retrospective study in which 20 cases of larynx stenosis from 2008 until 2018 were evaluated. The study revealed a predominance of the pathology in men, especially from rural environment. The etiology of larynx stenosis was both iatrogenic and traumatic. Multiple surgical interventions classical and endoscopic were necessary, along with tracheostomy. In 7 cases there was the need for larynx stent to be mounted. There was no significant correlation between age, etiology and the site of stenosis and the removal of the tracheostomy. Larynx stenosis benefit in present by modern surgical techniques. Current therapeutic options include conservative therapy, endoscopic approach and external approach depending on the site, severity, morbidities of the stenosis. Even if technology is of great help in LS management of many patients, unfortunately there are still cases where therapy is very complex and with poor functional results.
Heterogeneidad clínica y mutacional en pacientes colombianos con Pelizaeus Merzbacher
Authors: Velasco-Parra Harvy Mauricio , Maradei-Anaya Silvia Juliana , Acosta-Guio Johanna Carolina , Arteaga-Diaz Clara Eugenia , Prieto-Rivera Juan Carlos
Published: November 2018

La enfermedad de Pelizaeus Merzbacher (PMD) es una leucodistrofia ligada al X que causa encefalopatía espástica crónica en la infancia. Su etiología es genética, por duplicaciones (u otros trastornos de la dosis génica) o mutaciones puntuales del gen PLP1, lo que condiciona la formación anormal de las vainas de mielina principalmente en el Sistema Nervioso Central. Clínicamente se caracteriza por un cuadro de retardo del neurodesarrollo, nistagmus y espasticidad, con neuroimágenes que evidencian la dismielinización. Presentamos una serie de 7 casos colombianos con PMD, en la que describimos fenotípica y genotípicamente la heterogeneidad de esta enfermedad en nuestra población. Se realizó al 85% de los pacientes diagnóstico molecular confirmatorio (2 pacientes estaban relacionados con otros), y en ellos se reportan mutaciones puntuales en PLP1 en el 71.5% de los pacientes y duplicaciones completas del PLP1 en el restante 28.5%. Dado lo anterior, sugerimos que el abordaje diagnóstico confirmatorio en población colombiana debería iniciar con secuenciación del gen afectado, contrario a lo sugerido en literatura mundial en la que se inicia con estudio para duplicación/deleción.
Netrin 1 and Alpha-Methyl Acylcoenzim-A Racemase in diagnosis of prostate cancer
Authors: Koseoglu Ersin , Tuncel Altug , Balci Melih , Kaya Oguzhan , Aslan Yılmaz , Guzel Ozer , Meric Yilmaz Fatma , Atan Ali
Published: November 2018

Objectives: To investigate serum and urine levels of Alphamethylacyl-CoA-racemase (AMACR) and Netrin 1 in patients with and without prostate cancer and to determine whether these markers could be used as alternatives in diagnosis of prostate cancer instead of serum prostate specific antigen (PSA) levels.
Methods: One hundred and seventy five patients between 45-75 years to whom transrectal ultrasound guided biopsies were performed for abnormal serum PSA levels or digital rectal examinations were included. The levels of AMACR and Netrin 1 levels of blood and urine samples of 5 mL those were taken prior to biopsies were measured.
Results: The mean age of the patients was 62.7 ±6.4 years. Prostate cancer was detected in 40 patients (22.8%) while 135 of them (77.2%) were diagnosed as benign prostate hyperplasia (BPH). In BPH group, serum and urine levels of AMACR and Netrin 1 were 13.4 ±16.9 ng/mL; 7.1 ±3.4 ng/mL; 164.1 ±46 pg/mL and 19.5±5 pg/mL respectively. The levels of serum and urine levels of AMACR and Netrin 1 were 10.2 ±9.8 ng/mL; 6.8 ±2.5 ng/mL; 159.1 ±44.1 pg/mL and 20.1 ±5.3 pg/mL respectively in prostate cancer group. There was no statistically significant difference or correlation between these two groups serum and urine AMACR and Netrin 1 results
Conclusions: Serum and urine levels of AMACR and Netrin 1 were not found to be alternatives for serum PSA levels in the diagnosis of prostate cancer in this study.
Reevaluating nutrition as a risk factor for cardio-metabolic diseases
Authors: López Jaramillo Patricio , Otero Johanna , Camacho Paul Anthony , Baldeón Manuel , Fornasini Marco
Published: November 2018

Introduction: The consumption of saturated fats is considered a risk factor for cardiovascular diseases.
Objective: Review published papers on the role of macro-nutrient intake in cardiovascular risk.
Results: Recent reports from the PURE study and several previous metaanalyses, show that the consumption of total saturated and unsaturated fat is not associated with risk of acute myocardial infarction or mortality due to cardiovascular disease. High carbohydrate intake was associated with the highest risk of total and cardiovascular mortality, while total fat consumption or of its different types was associated with a lower risk of mortality. A high consumption of fruits, vegetables and legumes was associated with lower risk of total mortality and non-cardiovascular mortality. The consumption of 100 g of legumes, two or three times a week, ameliorated deficiencies of the nutrients contained in these foods and was associated with a reduction in the risk of developing chronic noncommunicable diseases.
Conclusion: A healthy diet should be balanced and varied, be composed of a proportion of complex carbohydrates rich in fibber between 50-55% of the daily energy consumed, of saturated and unsaturated fat (25-30%), animal and vegetable protein (including legumes) between 15-25%, vitamins, minerals and water. These nutrients are abundantly present in fruits, vegetables, cereals, legumes, milk and its derivatives, eggs and meats, so public policies should promote the availability and access to these nutrients within primary prevention programs to reduce the growing prevalence of cardio-metabolic diseases.
High Blood Pressure prevention and control: from evidence to action
Authors: Barrera Lena
Published: November 2018

The Pan American Health Organization (PAHO) with the World Hypertension League has established the 17th May to promote the prevention and control of High Blood Pressure (HBP). Currently nearly 1.13 billion of adults suffer from HBP (blood pressure ≥140/90 mm Hg) worldwide. While HBP prevalence decreased in high income countries (HIC) between 1975 and 2015, the opposite trend was observed in low- and middle- income countries (LMIC). Particularly, in Latin American and Caribbean countries the prevalence decreased from 40.6% to 26.8% and from 26.8% to 19.4% for men and women between 45 to 49 years old respectively. However, in 2015, HBP accounted for 8.9 of the total of disability adjusted life years (DALYS) and was associated with 4.9 million, 2.0 million and 1.5 million deaths due to ischemic heart disease, hemorrhagic stroke and ischemic stroke respectively. Therefore, HBP is the leading cardiovascular risk factor worldwide. In Colombia, the last National Health Survey reported a global prevalence of 22.8% and nearly 60% for those between 60 and 69 years in 2007
Cali Cancer Registry Methods
Authors: García Luz Stella , Bravo Luis Eduardo , Collazos Paola , Ramírez Oscar , Carrascal Edwin , Nuñez Marcela , Portilla Nelson , Millan Erquinovaldo
Published: November 2018

In this article by Garcia et al, On corresponding author is incorrect: “Luz Stella Garcia, Registro Poblacional de Cancer de Cali. Calle 4B 31-00 Oficina 4003, Edificio 116, Cali, Colombia. E-mail: luz.garcia@correounivalle. edu.co.” The correct corresponding author should be: “Luis Eduardo Bravo, Director Registro Poblacional de Cáncer de Cali. Calle 4B 31-00 Oficina 4003, Edificio 116, Cali, Colombia. E-mail: luis.bravo@correounivalle.edu.co”
22q11.2 deletion detected by in situ hybridization in Mexican patients with velocardiofacial syndrome-like features.
Authors: Ramírez Velazco Azubel , Rivera Horacio , Vásquez Velázquez Ana Isabel , Aguayo Orozco Thania Alejandra , Delgadillo Pérez Saturnino , Domínguez María Guadalupe
Published: November 2018

Introduction: Deletion 22q11.2 occurs in 1:4,000-1:6,000 live births while 10p13p14 deletion is found in 1:200,000 newborns. Both deletions have similar clinical features such as congenital heart disease and immunological anomalies.
Objective: We looked for a 22q11.2 deletion in Mexican patients with craniofacial dysmorphisms suggestive of DiGeorge or velocardiofacial syndromes and at least one major phenotypic feature (cardiac anomaly, immune deficiency, palatal defects or development delay).
Methods: A prospective study of 39 patients recruited in 2012-2015 at the Instituto Mexicano del Seguro Social at Guadalajara, Mexico. The patients with velocardiofacial syndrome-like features or a confirmed tetralogy of Fallot (TOF) or complex cardiopathy were studied by G-banding and fluorescence in situ hybridization (FISH) with a dual TUPLE1(HIRA)/ARSA or TUPLE1(22q11)/22q13(SHANK3) probe, six patients without the 22q11.2 deletion (arbitrarily selected) were tested with the dual DiGeorge II (10p14)/D10Z1 probe.
Results: Twenty-two patients (7 males and 15 females) had the 22q11.2 deletion and 17/39 did not have it; no patient had a 10p loss. Among the 22 deleted patients, 19 had congenital heart disease (mostly TOF). Twelve patients without deletion had heart defects such as TOF (4/12), isolate ventricular septal defect (2/12) or other disorders (6/12).
Conclusion: In our small sample about ~56% of the patients, regardless of the clinical diagnosis, had the expected 22q11.2 deletion. We remark the importance of early cytogenetic diagnosis in order to achieve a proper integral management of the patients and their families.
Prophylaxis with melatonin for primary stabbing headache in pediatrics: a case report
Authors: Bermúdez Salazar Mauricio , Rojas Cerón Christian Andrés , Arana Muñoz Ronald Santiago
Published: November 2018

Introduction: Primary stabbing headache (or “ice pick headache”) is an alteration characterized by brief jabs (short stabs of pain, lasting ~3 seconds), which appear spontaneously, irregularly, and affecting unilaterally or bilaterally. Indomethacin has traditionally been used as the main therapeutic option. However, this drug is ineffective in a considerable percentage of patients and can generate multiple adverse effects that occur at therapeutic doses.
Clinical case: A 7-year-old male patient with primary stabbing headache of mild to moderate intensity, lasting 3 to 4 seconds, without relevant history, with normal neurodevelopment, neurological examination and neuroimaging; no triggers were identified. It was started therapeutic trial with Coenzyme Q10; however, no improvement in the symptoms was identified.
Treatment and outcomes: A therapeutic management was carried out with Melatonin, which led to complete remission of the symptoms; without adverse effects in the posterior follow-up months.
Clinical and scientific relevance: There is little information regarding effective and safe treatments for primary stabbing headache in children. The present case identifies Melatonin as an innovative, effective and safe therapeutic alternative in the treatment of primary stabbing headache in children. This is a significant advance in the understanding of primary stabbing headache in the pediatric population.
Conclusion: Melatonin may be an effective and safe therapeutic option for the treatment of primary stabbing headache in pediatric patients. It is necessary to deepen its research, in order to establish its use in a clinical practice guide.
FIBROSIS QUÍSTICA EN PEDIATRÍA Y COMPROMISO PONDOESTAURAL
Authors: VELASCO BENITEZ CARLOS ALBERTO
Published: November 2018

La fibrosis quística del páncreas, entidad hereditaria, autosómica recesiva, producto de las mutaciones en el gen que codifica la proteína reguladora de la conductancia transmembrana, es una entidad que si no se diagnóstica a tiempo es desvastadora desde el punto de vista nutricional. El compromiso de la fibrosis quística en el niño es multisistémico, principalmente respiratorio y digestivo (intestino, páncreas, hígado), que repercute en lo nutricional, y por ende la calidad de vida de los niños. El estudio de Jassim et al., presentado en este suplemento, busca evaluar el grado de afectación del crecimiento pondoestatural como efecto de la fibrosis quística del páncreas en los infantes que asisten a las IPS en Barranquilla entre 2013-2015. Jassim-Álvarez BR, Sara Quintero MA. Evaluación del grado de afectación del crecimiento pondoestatural como efecto de la fibrosis quística pancreática en infantes de 0 días de nacidos hasta los 18 años, que asisten a las Instituciones Prestadoras de Salud en Barranquilla (Centro de Atención Pulmonar: Clínica Porto Azúl) entre 2013 2015. Rev Gastrohnup 2015; 17 (3) Supl. 3: S5-S12
NUTRICIÓN EN EL NIÑO HIPERTENSO
Authors: MORENO GIRALDO LINA JOHANNA , HERRERA GENES ADELA
Published: November 2018

La Hipertensión Arterial (HTA) en niños es un problema creciente en salud. Con una frecuencia estimada en niños del 1-13%, dependiendo de la metodología usada, es uno de los factores de riesgo más importantes para el desarrollo de enfermedad cardiovascular y renal crónica. En 2004, el Cuarto Informe, establece que los valores normales de la presión arterial en niños dependen del género, edad, percentil de talla y para su clasificación se utilizan actualmente las tablas de la National High Blood Pressure Education Program Working Group on High Blood Pressure Children and Adolescents, con los percentiles 50, 90, 95 y 99 de presión arterial sistólica y diastólica. Entre los factores en la patogenia de la HTA primaria ó esencial en pediatría está la obesidad, relacionada con el aumento del gasto cardíaco y del volumen intravascular, aumento de la actividad del sistema simpático, lesión endotelial por radicales libres, aumento de la generación de angiotensina a partir del tejido adiposo, hiperinsulinemia con aumento en la reabsorción de sodio y del tono simpático, de la leptina, además de aterosclerosis temprana, trastornos del sueño relacionados con síndromes de apnea e hipopnea. En los niños, las diferentes guías de manejo incluyendo las de la Organización Mundial de la Salud y de la Sociedad Internacional de Hipertensión (OMS/ISH), se plantean como objetivo terapéutico reconocido ampliamente, que una disminución en el consumo de sodio en niños y adolescentes se ha asociado con reducción en la PA, entre 1 a 3 mmHg. Por lo anterior, teniendo en cuenta las complicaciones en edades tardías de consumo de sal de la dieta desde la infancia y la aparición más frecuente de niños pequeños se debe determinar las necesidades de sodio en la dieta y dentro de las recomendaciones se debe preferir alimentos de origen natural y en lo posible no se debe agregar sal a las preparaciones en el niño menor de 2 años.
DOLOR ABDOMINAL Y PARÁSITOS INTESTINALES EN NIÑOS
Authors: VELASCO BENÍTEZ CARLOS ALBERTO
Published: November 2018

Es conducta regular que ante todo niño con dolor abdominal en nuestros países en vía de desarrollo, el parasitismo intestinal sea tenido en cuenta. En este numero de la Revista Gastrohnup se presenta un artículo sobre Dolor abdominal en niños en donde se describe la fisiopatología del dolor abdominal así como semiológicamente como diferenciarlo en agudo, crónico y funcional, y dentro de estos, cuál es el papelque juegan los parásitos intestinales. En un segundo artículo de este número se realiza una revisión epidemiológica de un geohelmilto causante de dolor abdominal, el Ascaris lumbricoides y dentro del mismo su posible asociación con la presencia de dolor abdominal en niños. Finalmente hay un par de artículos sobre nutrición pediátrica: el primero de ellos sobre la alimentación normal en el lactante normal y el segundo sobre nutrición en el niño con enfermedad renal. El resto del numero de la Revista Gastrohnup está dedicado a una diversidad de artículos resultado de la productividad académica de algunos de los profesores de la Facultad de Salud de la Universidad delValle.
EPIDEMIOLOGÍA DEL ÁSCARIS LUMBRICOIDES EN PEDIATRÍA
Authors: GRIJALVA ZULUAGA DANIEL SANTIAGO
Published: November 2018

Los parásitos intestinales son un problema grave en países en vía de desarrollo, entre ellos encontramos los geohelmintos siendo Áscaris lumbricoides el principal por su alta prevalencia causando una infección conocida como ascariasis que afecta principalmente niños en edad preescolar y escolar estando asociada a factores como falta de higiene, deficiencia en el saneamiento básico, geofagia, infección materna, falta de agua potable, consumo de alimentos crudos y sin lavar, etc. Este artículo es una revisión de la literatura reciente que examina la prevalencia de Áscaris lumbricoides en países en desarrollo sobretodo en Latinoamérica.
Hacia una educación superior inclusiva
Authors: Moreno Parra Héctor Alonso
Published: November 2018

El proyecto de Estado-nación multicultural promovido por las sociedades contemporáneas se basa en el reconocimiento de la diversidad, en los derechos diferenciados y en la igualdad como condición estructural de la vida en comunidad. Este reconocimiento significa legitimar las luchas históricas de los grupos étnicos vernáculos y las minorías sociales, que han sido temas paradigmáticos de las luchas por la participación económica, social y política. El análisis de las perspectivas de diversidad y multiculturalismo para la construcción de un Estado-nación inclusivo y equitativo implica el reconocimiento del derecho a la identidad cultural de los grupos étnicos y culturalmente diferenciados, apreciando y aprendiendo sobre ellos y determinando su ubicación territorial mediante la construcción permanente de un diálogo intercultural. Este artículo es un estudio histórico que analiza la importancia del reconocimiento constitucional de la multiculturalidad para comprender los conflictos étnicos y culturales en la sociedad colombiana en el marco del estado social de derecho como mecanismo de construcción de diálogos interculturales, que haría posible formar una sociedad más inclusiva y equitativa, que trascienda el modelo de Estado monocultural sobre el cual se han construido las repúblicas latinoamericanas desde su fundación.