bluuebunny/crossref_metadata_2025 huggingface dataset:
Prospects for the transfer of innovation in the rural world – the case of the innovation platform “Champs d’innovation” in Normandy Region, France
Authors: Ceapraz Ion Lucian , Fourati Fatma , Sauvée Loïc
Published: October 2023

This study focuses on the evaluation of the transfer of innovation by taking the example of the ‘Innovation Platform’ (IP) called “Champs d’innovation”, a project initiated by the Normandy region, France. The study focuses mainly on the modalities of innovation transfer and the complementarities between the different interfaces for the transfer of innovative solutions in the agricultural world. The first results of the study highlight the determinants of the transfer of innovative solutions. Furthermore, from an empirical point of view, the study provides a better understanding of innovation systems in general and in agriculture in particular, and more specifically of the different facets of innovation transfer and the measurement of the transferability of innovative solutions between different stakeholders.
Financial Innovation and Corporate Governance for Sustainability of Islamic Financial Institutions: Challenges & Prospects
Authors: Ahmad Ashfaq
Published: October 2023

The financial sector is an important component of the financial system that could help to attain socio-economic development. Islamic Financial Institutions (IFIs) are considered a vital part of financial institutions and playing pivotal role in innovation, digitization and technology driven market. Moreover, governance structure and corporate governance practices are main drivers of sustainability of IFIs. This study investigates the importance of financial innovation and corporate governance practices for sustainable performance of IFIs. Target respondents were approached for data collection to identify the potential benefits and prospects of financial innovation and corporate governance practices. Researcher approached board members, shariah advisors and senior management of IFIs as well as representatives of SBP, SECP and other professional bodies for discussions, deliberations, and professional interactions by arranging several sessions. Data was collected and analyzed to identify the challenges and prospectus. Findings indicate that IFIs in Pakistan had experienced unprecedented growth in almost all aspects including the size, volume, assets, branches, and contribution to the socio-economic profile of Pakistan during the recent years. IFIs are directly influenced by financial innovation and facing a rapid change in the perception and expectations of the stakeholders who are demanding innovative products, technology-driven processes, and customized services. Similarly, sustainability and effective governance is one of the important elements for the survival of IFIs in the highly competitive financial environment with ever changing products. Findings could enhance the understanding and learning of the relevant stakeholder for better decision making.
From potential words to actual words: A pronunciation-integrated teaching model to facilitate productive oral vocabulary development
Authors: Mister Bianca
Published: October 2023

Facilitating the transformation of vocabulary from receptive to productive can be challenging for second language (L2) teachers. Although some studies have focused on understanding activities that promote productive vocabulary in written modes (e.g., Teng & Xu, 2022), little is known about the effect of activities on productive vocabulary in spoken modes. To fill this gap, this paper presents an innovative pronunciation-integrated teaching model to facilitate productive oral vocabulary development. Pronunciation training and vocabulary teaching are typically seen as distinct areas of teaching English as a Second Language; yet, in the context of developing productive vocabulary to be used in speaking, they are highly complementary. Therefore, the innovativeness of the model presented here is the integration of pronunciation training into vocabulary-focused. The teaching model is helpful because it provides teachers with a practical guide for the creation of activities that can be used for classroom teaching of productive oral vocabulary.
Interactive methods used in collaborative writing in the online ESL classroom
Authors: Chojczak Diana , Starford Ashey
Published: October 2023

The last few years have amplified the use of digital technology in the second language (L2) classroom due to the emergence of COVID-19. Students were forced to study online, and, as a result, changing the interaction among students became crucial. While most English Language Intensive Courses for Overseas Students (ELICOS) classrooms have since returned to face-to-face delivery, many providers are now considering the potential benefits of online learning and the strategies that make the platform and classroom interaction effective. One method of facilitating online interaction is collaborative writing (i.e., co-writing). Co-writing refers to two or more individuals producing work and contributing to a task together. While not a new phenomenon in face-to-face settings, this research project closely investigates the methods that students use to interact while completing co-writing tasks in an online environment and the impact these may have on L2 learning. The data, taken over five weeks, was collected from 15 adult English for Academic Purposes students in an online ELICOS classroom. Results showed areas of improvement in co-writing and a perception among students that co-writing was helpful. The paper aims to contribute to greater understanding and improved co-writing delivery and practice for ESL students and practitioners.
PENGARUH FISIKOLOGI RASA AMAN SOSIAL PENGHARGAAN DAN AKTUALISASI DIRI TERHADAP KINERJA KARYAWAN PT DALIJO ULAM UPADI DI MUARA BADAK
Authors: Nasution Aliciar Amalia , Abdullah Rahim , Aryani Farida
Published: October 2023

In an effort to realize optimal performance with quality human resources CV. Dalijo Ulam Upadi makes various efforts to motivate employees, one of which is by providing compensation, namely basic salary (monthly) and bonuses. However, from the information that researchers received based on reports from other employees, there are several symptoms that occur in some employees, such as a lack of employee work enthusiasm, including being often late, often missing work hours and employees being slow in completing work, even though this is still considered a problem. which is light but will be detrimental to the company if this is allowed to drag on. For this reason, researchers really want to provide motivation that is based on the application of several theories put forward by experts, whether they can be implemented or not so that workers are enthusiastic about carrying out their work, do not miss work hours and arrive on time because they have been well motivated through several of these methods. This study aims to determine the effect of physiology, security, social, respect and self-actualization simultaneously and partially on employee performance on the CV. Dalijo Ulam Upadi in Muara Badak. The sample in this study were employees at CV. Dalijo Ulam Upadi, amounting to 27 people. The data analysis technique of this research is multiple regression, with hypothesis testing using the f test and t test. And the results of the research obtained are simultaneously and partially the five variables of this study include physical, social security, appreciation and self-actualization variables that have a significant effect on employee performance at CV Dalijo Ulam Upadi in Muara Badak.
PERAN KELOMPOK TANI DALAM MENINGKATKAN PENDAPATAN PADA TANI KUMPA RAYA DI DESA MANUNGGAL DAYA
Authors: Sudarso  , Luthman Awang Yacoub , Hendra
Published: October 2023

The Role of Farmer Groups in increasing income for Kumpa Raya Farmers in Manunggal Daya Village. The Government of Kutai Kartanegara Regency formed a joint farmer group which aims to provide additional knowledge on renewal of systems in agriculture in order to increase the income of the people of Kutai Kartanegara Regency, especially in Manunggal Daya Village. In addition to providing additional knowledge to participants so that they can understand the process of group growth, group development is to improve group capabilities and the importance of combined farmer groups as business actors in implementing agribusiness. The purpose of this study was to determine the role of the Kumpa Raya farmer group in increasing the income of farmers in Manunggal Daya Village, in addition to knowing the role of farmer groups from an economic point of view in increasing the income of farmers in Manunggal Daya Village. The Kumpa Raya farmer group consists of 26 members, 3 of whom are administrators of the farmer group and the remaining 23 people are members of the farmer group, making a total of 26 people. From the results of the research it was found that the role of farmer groups is indeed very important in addition to being able to increase income or the economy of the community, farmer groups also act as a forum for deliberations, a place to maintain and develop knowledge, skills and mutual cooperation in farming among its members (production units). For this reason, the Kumpa Raya farmer group is very beneficial for the people of Manunggal Daya Village.
Rancangan Sistem Informasi Inventory Management Koleksi Masuk pada Perpustakaan STAIN Sultan Abdurrahman Kepulauan Riau
Authors: Astuti Santi Puji , Fatwanto Agung
Published: October 2023

Collection inventory is something that has been known for a long time in the library world. With the development of technology, it is not impossible if incoming collection inventory activities are carried out with the help of updated application designs. One of the designs that can be applied is inventory management. The purpose of this writing is to assist and facilitate the work on the inventory of incoming collections at library of STAIN Sultan Abdurrahman Riau Archipelago. The method used in this research is a literature study. The desired results with the development of this information system design are to simplify, accelerate incoming collection inventory activities and ease the workload of librarians in reporting accountability to library leaders in incoming collection inventory activities at library of STAIN Sultan Abdurrahman Riau Archipelago.
Illumination on the Bamboo Manuscript "Karang Mindu" Collection of Bakhtiar Hanif Kerinci
Authors: Azizah Faras Puji
Published: October 2023

The Karang Mindu manuscript is one of the ancient manuscripts originating from Kerinci, one of the collections of Bakhtiar Hanif, which we know that these ancient manuscripts are very important to protect, because they are relics of our ancestors that have high historical value. Not only that, from ancient manuscripts we can find out about the culture of the past about the illumination on the bamboo manuscript "Karang Mindu" collection of Bakhtiar Hanif Kerinci. The purpose of this article is to find out about the manuscript. Overall, the method used in this research is to use a qualitative method using a literature study, by collecting the main source from the EAP Library with documentation number EAP 117/63/1/15, besides that the author also collects sources from various previous studies, books, articles, journals, which are related to the research theme. The result of this research is the content of the manuscript text Karang Mindu explains about a poet whose love is unrequited, besides that there are also interesting illuminations such as Pucuk Rebung, and Keluk Paku. The manuscript motive also describes the life of ancient people who always utilized nature for their needs. Therefore, studying the illuminations in the manuscript helps to strengthen and maintain Kerinci's cultural heritage or local wisdom.
The Smell of Opium in Minangkabau: Tradition of Betel Chewing and Smoking Tobacco in the 19th Century
Authors: Nasir Muhammad
Published: October 2023

One of the historical themes of the Padri movement in Minangkabau in the 19th century was about eradicating the habit of smoking madat that occurred in Minangkabau society. The habit of smoking opium cannot be read at face value without investigating how opium-derived opium is used in the daily habits of the Minangkabau people. For example, in the habit of chewing betel nut and smoking tobacco. Therefore, using a social history approach, this paper will describe how opium is involved in the habit of chewing betel nut and smoking tobacco in the Minangkabau community. Thus, this paper will help explain how to understand the social context of the Padri in eradicating habits that they consider to be behavior that is not in accordance with Islamic teachings.
Whether serum albumin/leukocyte ratio combined with Go-FAR score more accurately predicts the neurological outcome of patients who suffered cardiac arrest
Authors: MAO Xiaojing , YANG Wenbin , ZHANG Hujie
Published: October 2023

Objective: To investigate whether serum albumin/leukocyte ratio combined with good outcome score after resuscitation (GO-FAR score) can improve the prediction of neurological outcomes in patients with cardiac arrest, so that clinical decisions can be made earlier and futile resuscitation can be avoided. Methods:The data of 72 patients with cardiac arrest rescued 2020.01.01-2022.04.30 in the Seventh Affiliated Hospital of Sun Yat-sen University were collected, and the GO-FAR score and albumin/leukocyte ratio of all patients were calculated. The main research outcome was the neurological outcome within one month after cardiac arrest. The brain function performance score (CPC score) was used for assessing neurological outcomes, It was divided into two groups:a good prognosis group (CPC score 1-2) and a poor prognosis group (CPC score 3-5). Multivariate Logistic analysis and ROC curve analysis were performed on the data of the two groups, and conclusions were drawn. Result:Univariate and multivariate analysis found that the albumin/leukocyte ratio and GO-FAR score in the poor prognosis group were lower than those in the good prognosis group, and the difference between the two groups was statistically significant (P < 0.05).The results of ROC curve analysis found that the area under the curve of ALB/WBC, GO-FAR score, and ALB/WBC + GO-FAR score were: 0.782 (95% CI: 0.662 to 0.903), 0.677 (95% CI: 0.493 to 0.862), 0.841 (95% CI: 746-0.936), P < 0.05, and the difference was statistically significant. Malignant tumor, shock rhythm, albumin, and leukocytes were all influencing factors for functional outcomes in patients with cardiac arrest. Conclusion:The combination of GO-FAR score and albumin/leukocyte ratio can better predict neurological outcomes in patients with cardiac arrest, but still cannot make instructions to stop resuscitation. More research is needed to confirm.
Creation of a oblique colon valve: a new methods to wake up the stem cell of colon
Authors: HE Hanzhong , TANG Zongyi , DENG Gaoyan
Published: October 2023

Objective: To find out a similar and better methods to increase colon absorptive function. Methods: Oblique colon valves were created in colons of rats with the massive resection of the small bowels, and the rats were compared with group with traditional colon valves, and short bowel syndrome (SBS) group. The rats were observed for 30 weeks.Results:The rats in groups with colon valves were heavier than that in control group. And rats with oblique colon valves had less obstruction. Conclusions: Oblique colon valve was a better methods to increase the absorptive function of colon.
Micronodular thymic carcinoma with lymphoid hyperplasia : A case report and review of the literature
Authors: YIN Yin , ZHANG Qiwei
Published: October 2023

Cases of micronodular thymic carcinoma with lymphoid hyperplasia are rare and are easily treated like common thymic carcinoma in clinical treatment. The clinical data of a 64-year-old woman admitted to the Seventh Affiliated Hospital of Sun Yat-sen University who was diagnosed with micronodular thymic carcinoma with lymphatic stroma after surgery are reported, and its characteristics and treatment methods are discussed in combination with literature.
Spectral pulsation dynamics of soliton molecules in ultrafast fiber lasers based on pump intensity modulation
Authors: Fang Zhen , Yu You , Zhao Qiu-Ye , Zhang Yu-Dong , Wang Zhi-Qiang , Zhang Zu-Xing ,   School of Flexible Electronics (Future Technology), School of Electronic and Optical Engineering, Nanjing University of Posts and Telecommunications, Nanjing 210023, China,   Key Laboratory of Optoelectronic Information Acquisition and Control, Ministry of Education, Anhui Provincial Laboratory of Information Materials and Intelligent Perception, Anhui University, Hefei 230601, China
Published: October 2023

This study employs real-time Fourier transform spectroscopy to investigate the pulsation dynamics of soliton molecules in a mode-locked erbium-doped fiber laser, by modulating pump intensity. By controlling the driving voltage of the pump source, we systematically observe and characterize the influence of external modulation signals on the amplitude, period, pulsation frequency, and the relative phase evolution among the pulsating soliton molecules in their spectra.

The results demonstrate that under specific conditions of pump intensity modulation, the pulsation period of soliton molecule spectra can be precisely regulated by the pump modulation frequency. At the same time, the amplitude of soliton molecule pulsations and the evolution of relative phase among the solitons are intricately tied to the pump modulation frequency. At lower modulation frequencies, such as 1 kHz, the relative phase among the pulses in the soliton molecule exhibits a sliding-type dynamics as a function of propagation time.

As the modulation frequency gradually increases to 5 kHz, a scenario emerges where three soliton molecules are generated. Notably, both the soliton spacing and relative phase undergo synchronous adjustments influenced by the pump modulation. With the modulation frequency further increasing, say, to 20 kHz, the relative phase evolution among the pulses within the soliton molecule gradually descends into chaos. This observation suggests the plausible existence of an inherent resonant frequency associated with pulsating soliton molecules, which has direct implications for their stability.

The findings of this research are of significance in advancing our comprehension of soliton molecule generation and enhancing their stability. In addition, they provide valuable insights into the broader domain of all-optical manipulation and applications of soliton molecules, and their application in pulse encoding in mode-locked laser systems.
Conservation spillover effect of UNESCO World Heritage Sites into surrounding landscapes
Authors: Hyland Emilia B. , Quinn John E.
Published: October 2023

Protected areas (PA) are one of the primary tools for conserving and protecting biodiversity, but their goals have evolved overtime beyond nature conservation to include supporting human communities within and adjacent to the PA. UNESCO World Heritage Sites (WHS) offer a unique perspective on the success of PAs as they fall under three categories, cultural, natural, and mixed heritage sites. The nature of these categories encapsulates the inclusion of human communities in the goals of the WHS. To understand the impact and relationship the WHS has with its surrounding landscape, we assessed changes in three indicators, land use and land cover (LULC), human footprint (HF), and forest landscape integrity index (FLII), across three spatial scales, 1, 10, 100 km from the WHS boundary. We found that there is a conservation spillover effect at least within 1 km of the WHS boundary. In this buffer zone, HF was low and FLII was high. FLII was lower and HF was higher at larger spatial scales. The relationship between the WHS and its surrounding landscape is one reason to support the WHS network, however, management of PAs should be more explicit about this relationship as well as relationships between individual PAs.
Validation of the HeLD-14 functional oral health literacy instrument in a general population
Authors: Flynn Priscilla , Ingleshwar Aparna , Chen Xing , Feuerstahler Leah , Reibel Yvette , John Mike T.
Published: October 2023

Background

Oral health literacy (OHL) is recognized as an important determinant of oral outcomes. Measuring OHL with a valid and reliable instrument that accurately captures the functional nature of this construct across cultures is needed. The short version of the Health Literacy in Dentistry scale (HeLD-14) shows promise as an appropriate instrument due to its inclusion of comprehensive domains hypothesized to comprise OHL. While studies validating the instrument in several languages have occurred, the number of dimensions in the various analyses range from one to seven. Validation of the HeLD-14 in a general English-speaking population is also lacking. The purpose of this study was to explore and confirm the dimensionality of the HeLD-14 in a general US English-speaking population.

Methods

The psychometric properties of HeLD-14 were evaluated in a sample of 631 participants attending the Minnesota State Fair. Construct validity was assessed using exploratory factor analysis (EFA) followed by confirmatory factor analysis (CFA) on the data set split into two groups. Internal consistency reliability was assessed using the Cronbach’s alpha coefficient. Concurrent validity was established between the HeLD-14 and the Oral Health Inventory Profile (OHIP-5) using Pearson’s correlation.

Results

EFA found, and CFA reinforced, a unidimensional structure of the HeLD-14. Cronbach’s alpha was acceptable at 0.92. Fit assessment also supported a unidimensional structure, comparative fit index = 0.992, Tucker-Lewis index = 0.991, root mean square error of approximation = 0.065, and standardized root mean square residual = 0.074. Concurrent validity analyses showed that the HeLD-14 correlated with the OHIP-5.

Conclusions

The HeLD-14 is a unidimensional reliable and valid instrument for measuring the oral health literacy in the general US English-speaking adult population.
Identification of ACHE as the hub gene targeting solasonine associated with non-small cell lung cancer (NSCLC) using integrated bioinformatics analysis
Authors: Liu Tong , Zhang Boke , Gao Yating , Zhang Xingxing , Tong Jiabing , Li Zegeng
Published: October 2023

Background

Solasonine, as a major biological component of Solanum nigrum L., has demonstrated anticancer effects against several malignancies. However, little is understood regarding its biological target and mechanism in non-small cell lung cancer (NSCLC).

Methods

We conducted an analysis on transcriptomic data to identify differentially expressed genes (DEGs), and employed an artificial intelligence (AI) strategy to predict the target protein for solasonine. Subsequently, genetic dependency analysis and molecular docking were performed, with Acetylcholinesterase (ACHE) selected as a pivotal marker for solasonine. We then employed a range of bioinformatic approaches to explore the relationship between ACHE and solasonine. Furthermore, we investigated the impact of solasonine on A549 cells, a human lung cancer cell line. Cell inhibition of A549 cells following solasonine treatment was analyzed using the CCK8 assay. Additionally, we assessed the protein expression of ACHE, as well as markers associated with apoptosis and inflammation, using western blotting. To investigate their functions, we employed a plasmid-based ACHE overexpression system. Finally, we performed dynamics simulations to simulate the interaction mode between solasonine and ACHE.

Results

The results of the genetic dependency analysis revealed that ACHE could be identified as the pivotal target with the highest docking affinity. The cell experiments yielded significant findings, as evidenced by the negative regulatory effect of solasonine treatment on tumor cells, as demonstrated by the CCK8 assay. Western blotting analysis revealed that solasonine treatment resulted in the downregulation of the Bcl-2/Bax ratio and upregulation of cleaved caspase-3 protein expression levels. Moreover, we observed that ACHE overexpression promoted the expression of the Bcl-2/Bax ratio and decreased cleaved caspase-3 expression in the OE-ACHE group. Notably, solasonine treatment rescued the Bcl-2/Bax ratio and cleaved caspase-3 expression in OE-ACHE cells compared to OE-ACHE cells without solasonine treatment, suggesting that solasonine induces apoptosis. Besides, solasonine exhibited its anti-inflammatory effects by inhibiting P38 MAPK. This was supported by the decline in protein levels of IL-1β and TNF-α, as well as the phosphorylated forms of JNK and P38 MAPK. The results from the molecular docking and dynamics simulations further confirmed the potent binding affinity and effective inhibitory action between solasonine and ACHE.

Conclusions

The findings of the current investigation show that solasonine exerts its pro-apoptosis and anti-inflammatory effects by suppressing the expression of ACHE.
County-level integrated media center promotes cultural inheritance and innovation with "short video" as the carrier
Authors: Zun Jiao , Lyu Chunwei
Published: October 2023

As a public opinion position to convey the spirit of the Party Central Committee and national policies, the Integrated Media Center plays a vital role in publicity work. Our country is vigorously promoting rural revitalization. Whether it can properly define its role and clarify its work priorities is directly related to the new tasks under the new situation in an all-round way. The popularization of the Internet has enabled many rural users to sell agricultural products and promote rural culture through short videos, which has gained considerable economic and social benefits. However, there are also some problems in the process that hinder further development. The integrated media center has the advantages of understanding the direction of publicity, familiar with the local economic and cultural development, and mastering the production of short videos. If the integrated media assists in the production and promotion of short videos, it will have better publicity effects. This article analyzes the problems in the promotion process of short videos for rural users, in order to establish effective working ideas for the media center and promote local cultural inheritance and innovation.
A study on the relationship between attitudes towards sports and self-efficacy levels of individuals doing leisure time activities
Authors: Tapşın Faik Orhun , Tapşın Fuat Orkun , Özdemir Emin , Selvi Sabit , Alev Alpay , Yenel İbrahim Fatih
Published: October 2023

The purpose of this study was to research the relationship between attitudes towards sports and self-efficacy levels of individuals who do leisure-time activities. 894 people voluntarily participated in our study. The personal information form, the attitude scale towards sports developed by Koçak (2014) and the general self-efficacy scale developed by Sherer, et al. (1982) and adapted to Turkish by Yıldırım and İlhan (2010) were used in the study. The data were analyzed in the SPSS 25.0 package software. Furthermore, statistical frequency analysis and reliability coefficient calculations were used and since the data were normally distributed, Independent Samples t-test was used for pairwise cluster comparisons and the Anova test was used for more than two comparisons. Analyses were conducted at a confidence interval of 95%. According to the results of the study, it was found that the total mean score of the participants' attitude towards sports (89.62) and the mean score of self-efficacy (60.08) were above the medium level. A positive and low-level significant relationship was found between the participants' general attitude towards sports (r= ,221), psychosocial development (r= ,215), physical development (r= ,206), mental development (r= ,123) and self-efficacy. As a result, it was found that the participants' self-efficacy level increased as the mean scores of the general attitude towards sports and the mean scores of the sub-dimensions increased.
App atmospherics, personality factors and technology acceptance behaviour towards the adoption of mobile banking apps – a systematic literature review
Authors: Behera Mukti Prakash , Deb Tanmoy , Prasad KDV
Published: October 2023

Mobile banking apps have become increasingly popular in recent years, providing customers with a convenient and secure way to manage their finances. These apps have transformed the way we conduct financial transactions and have revolutionized the banking industry. However, despite the widespread adoption of mobile banking apps, there is still a significant gap in our understanding of the factors that influence customers' acceptance of these apps. This systematic literature review aims to provide a comprehensive overview of the current state of research in this area based on app atmospherics, personality factors, and technology acceptance behaviour. The review analysed 40 papers published between 2019 to 2023 to synthesize the evidence and identify key factors that influence the adoption and intention to use mobile banking apps. One of the key findings of the review is that app atmospherics, including the visual design, functionality, and interactivity of mobile banking apps, significantly influence customers' technology acceptance behaviour. Customers are more likely to adopt mobile banking apps that are visually appealing, user-friendly, and interactive. Additionally, technology acceptance behaviour, such as perceived usefulness, perceived ease of use, and perceived trustworthiness, also plays a crucial role in shaping customers' attitudes towards mobile banking apps. The review also identified personality factors such as emotions and attitudes that significantly influence the adoption and intention to use mobile banking apps. Customers who are open to change, innovative, and willing to take risks are more likely to adopt mobile banking apps than those who are not. Additionally, customer demographics, cultural differences, and technological advancements were identified as key factors that affect the adoption of mobile banking apps.  Banks and financial institutions must keep up with technological advancements to stay ahead of the competition and provide customers with the latest and most innovative technologies. This study has identified the key research gaps and suggest a theoretical framework for future research agenda.
Risk Factors for Hearing Loss in High-Risk Neonates at a Tertiary Care Centre in Central India: A Prospective Observational Study
Authors: Dhande Leena , Ganaboor Prerana , Hattewar Rasika , Jaiswal Chetan
Published: October 2023

Introduction: Hearing impairment and deafness are global issues that affect 5% of the world’s population, with nearly 34 million children requiring rehabilitation to address their hearing loss (HL). An approximately 10-20 fold higher incidence of audiological risk factors has been noted in Neonatal Intensive Care Units (NICUs), which translates that 2-5% of all newborns in NICUs may be affected. Early diagnosis of HL and intervention can be advantageous from the timely fitting of hearing aids or cochlear implants. Aim: The aim of this study was to evaluate the risk factors for HL in NICUs and Special Neonatal Care Units (SNCUs) at a tertiary care hospital in Central India. Materials and Methods: This prospective, observational, single-centre study was conducted from October 2019 to September 2021 in the Department of Paediatrics at Indira Gandhi Government Medical College and Hospital, Nagpur, Maharashtra, India. A total of 319 neonates at high risk for HL, discharged from NICUs and SNCUs, were included in the study. The association between risk factors like prematurity, low birth weight (LBW), Toxoplasmosis, Rubella, Cytomegalovirus, Herpes Simplex (TORCH) infections, neonatal asphyxia, neonatal sepsis, meningitis, exchange transfusion, assisted ventilation, and HL were studied. The chi-square test was used to assess the association between SNHL and risk factors. Results: The incidence of Sensorineural Hearing Loss (SNHL) was 3.76%. Neonatal asphyxia (p-value <0.01), exchange transfusion (p-value <0.001), TORCH infections (p-value < 0.001), meningitis (p-value <0.001), and assisted ventilation (p-value <0.001) were found to be significant risk factors associated with SNHL. Conclusion: Based on the assessment of risk factors, it was concluded that neonates should undergo hearing screening tests within the first month of life, and a diagnosis should be made by three months of age. This allows specialists to initiate treatment and intervention by six months of age, helping children with impaired hearing avoid the harmful consequences of semantic deprivation.
Correlation between Selected Micronutrient Status in Maternal Blood and Cord Blood of Newborn from a Tertiary Care Hospital in West Bengal, India: A Cross-sectional Study
Authors: Kunti Sanjoy Kumar , Chatterjee Sharmistha , Chakraborty Indranil
Published: October 2023

Introduction: The demand for most micronutrients increases during pregnancy for obvious reasons. Micronutrients like copper and zinc are indispensable co-factors for various enzymes in metabolism. The reduction in the concentration of serum iron and ferritin is a common phenomenon in pregnancy, and early diagnosis is crucial for favourable maternal and foetal outcomes. However, there is a dearth of studies on the metabolism of micronutrients in pregnancy. Aim: The aim of this cross-sectional study, conducted from July 2018 to February 2019 in the Department of Gynaecology and Obstetrics and the Department of Biochemistry, College of Medicine and Sagore Dutta Hospital, West Bengal, India, was to assess the serum levels of copper, zinc, and iron in maternal serum and foetal cord blood. Additionally, the study aimed to correlate the concentrations of these micronutrients between maternal serum and foetal cord blood. Materials and Methods: A total of 336 pregnant women of childbearing age, irrespective of gravida, were included in the study. Blood samples were collected from the pregnant women, and cord blood samples were collected from the foetal end in clot vials for the estimation of copper, zinc, and iron levels. Correlation was assessed between the concentration of these micronutrients in maternal serum and cord blood of the newborn. Data normality was determined using the Shapiro-Wilk normality tests, and the significance level was set at p-value ≤0.05. Results: The study included a total of 336 pregnant women in the age group of 18-33 years, with a mean age of 29.72±4.39 years. In maternal serum, the mean concentration of copper was 122.79±33.67 μg/dL, zinc was 78.47±27.62 μg/dL, and iron was 114.5±45.05 μg/dL. In foetal cord blood, the mean concentration of copper was 48.02±16.37 μg/dL, zinc was 75.82±27.64 μg/dL, and iron was 185.30±52.74 μg/dL. The correlation coefficients between maternal serum and foetal cord blood concentrations were statistically significant for zinc and iron (p-value<0.05). Additionally, the correlation was statistically significant for copper (p-value=0.030). The mean concentration of haemoglobin in maternal serum was 10.9±1.96 g/dL, compared to 14.05±2.13 g/dL in cord blood. The mean maternal serum ferritin was 73.53±56.15 μg/L, and the mean cord blood ferritin was 147.21±61.13 μg/L. Conclusion: The study demonstrated a positive correlation between the concentrations of iron and zinc in maternal serum and foetal cord blood, while a negative correlation was observed for copper concentration.
Effect of Two Different Doses of Intravenous Phenylephrine on the Prevention of Oxytocin Induced Hypotension in Lower Segment Caesarean Section Under Subarachnoid Block: A Randomised Controlled Study
Authors: Sharma Nihar , Agarwal Subrat , Modi Yogesh Chand , Yadav Amit , Yadav Jitendra , Sindhi Rashmi , Singh Ajay
Published: October 2023

Introduction: Postpartum haemorrhage with an atonic uterus is one of the leading causes of maternal mortality during Lower Segment Caesarean Section (LSCS) in nearly 50% of cases. Oxytocin is the most commonly administered drug for achieving post-delivery adequate uterine contractions and placenta expulsion, thereby preventing postpartum haemorrhage. Coadministration of phenylephrine during LSCS under spinal anaesthesia inhibits Oxytocin-induced hypotension. Aim: To compare the effectiveness of co-administration of two different doses of phenylephrine with oxytocin in preventing the incidence of Oxytocin-induced hypotension. Materials and Methods: A randomised, double-blinded controlled trial was in the Department of Anaesthesiology, SMS Medical College and Attached Group of Hospitals, Jaipur, Rajasthan, India from August 2021 to July 2022, involving 120 parturients with American Society of Anaesthelsiologists (ASA) grade second undergoing LSCS under subarachnoid block. They were randomised into three groups: Group A received oxytocin 3U with normal saline, Group B received Oxytocin 3U with Phenylephrine 50 mcg, and Group C received Oxytocin 3U with Phenylephrine 75 mcg administered intravenously over five minutes after the baby’s extraction. The incidence of hypotension, requirement for the total rescue dose of Phenylephrine, and side effects were recorded. Statistical analysis was performed using Analysis of Variance (ANOVA) and Chi-square test. Results: Demographic parameters such as age, height, weight, gestational age, and duration of surgery were comparable in all groups. The incidence of hypotension (Group A (Control): 77.5%, Group B (PE50): 47.5%, Group C (PE75): 22.5%, p<0.001), lowest Mean Arterial Pressure (MAP) after Oxytocin infusion (Group A: 67.80±6.16 mmHg, Group B: 68.23±3.96 mmHg, Group C: 72.50±5.87 mmHg, p<0.001), dose of rescue vasopressor requirements (Group A: 75.5±56.61, Group B: 40±50.89, Group C: 17.50±34.99, p<0.001), and incidence of side effects were significantly lower in Group C compared to Group B and Group A. Conclusion: Compared to Phenylephrine 50 mcg, the coadministration of Phenylephrine 75 mcg with Oxytocin 3U reduces the incidence of Oxytocin-induced hypotension and the need for rescue vasopressors during LSCS under subarachnoid block.
A Rare Case of Synchronous Cervical Squamous Cell Carcinoma and Ovarian Brenner Tumour in a Postmenopausal Female: A Histological Surprise
Authors: Jaiswal Riddhi , Dubey Deval Brajesh , Verma Prashant
Published: October 2023

Synchronous Tumours (ST) are defined as two or more neoplasms originating within six months of diagnosing the first neoplasm. Due to the rarity of synchronous cervical Squamous Cell Carcinoma (SCC) and ovarian Brenner tumours, their pathology has been poorly understood. These patients usually present with symptoms related to cervical cancer and are often diagnosed early. Since many synchronous tumours are incidentally discovered postoperatively, it is important to conduct thorough grossing and histopathological examinations. The primary differential diagnosis for synchronous tumours is multiple metastases from a single primary tumour. The management of multiple tumours is not well-defined and depends on various factors. In the present case, authors present a rare occurrence of synchronous neoplasms: cervical SCC and preoperatively undiagnosed benign Brenner tumour of the left ovary in a 52-year-old postmenopausal female. Immunohistochemistry helped rule out metastasis from a single primary and metastasis from cervical cancer to the ovary. The ovarian tumour showed immunoreactivity for GATA Binding Protein 3 (GATA) but was negative for Carcinoembryonic Antigen (CEA). The cervical SCC was immunopositive for CEA and p40, while no immunoreactivity was observed with GATA 3.
Immunoexpression of CD1a and Histopathology in Lesional and Non Lesional Skin in Psoriasis: A Cross-sectional Study
Authors: Yelavath Kavitha , Jyothi CH , Divyagna T , Kumari B Swapna
Published: October 2023

Introduction: Psoriasis is a long-lasting autoimmune disease mediated by T-lymphocytes and dendritic cells. Langerhans cells are a unique population of dendritic cells found in the epidermis, where they can be identified by Cluster of Differentiation 1a (CD1a) positivity. They play an important role in the pathogenesis of psoriasis. Aim: To evaluate the utility of immunoexpression of CD1a in the early diagnosis of psoriasis and to study the histopathology of skin biopsies from clinically diagnosed cases of psoriasis. Materials and Methods: A cross-sectional study was conducted from September 2017 to August 2019 at Gandhi Hospital, Secunderabad, Telangana, India. Skin biopsies were taken from 50 patients with psoriasis from the Outpatient Department (OPD). Histopathological features in early psoriasis were studied, and CD1a immunoexpression in lesional, perilesional, and distant skin was analysed. The data were analysed using Student’s t-test with the Statistical Package for the Social Sciences (SPSS) software. Results: Half of the cases were found in two age groups: 51-60 years (15 patients, 30%) and 11-20 years (10 patients, 20%). The majority of the cases were males (36 patients, 72%). Most of the biopsies were taken from the lower limb (24 patients, 48%), followed by the back (13 patients, 26%). In this study, the average number of CD1a positive Langerhans cells was highest (54.92±5.26) in perilesional skin compared to lesional skin (30±3.96), which was statistically significant (p-value=0.04). Conclusion: Based on the observations in this study, a strong positive reaction of CD1a in perilesional skin can be used to diagnose psoriasis in the early clinical stages, before full-blown clinical psoriatic plaques have appeared. Early diagnosis may prompt physicians to initiate treatment early
Factors Influencing Green Purchase Behavior: Price Sensitivity, Perceived Risk, and Attitude towards Green Products
Authors: Sheikh Alireza , Mirzaei Mahdi , Ahmadinejad Bahareh
Published: October 2023

The present study analyzes the effectiveness of consumer price sensitivity in expanding the use of green products. It investigates how the purchase behavior of Iranian consumers is affected by different aspects of perceived risk, such as financial, performance, psychological, and social risks. This study uses the four main concepts of ‘Perceived Risk’ (PR), ‘Attitude towards Green Products’ (AGP), ‘Price Sensitivity’ (PS), and ‘Green Purchase Behavior’(GPB) to develop a model to increase green purchase intention. This research uses an experimental study, using a survey method (questionnaire distribution)to confirm the hypotheses and discover its management concepts, and uses Structural Equation Modeling (SEM). The results show that the variable of “Perceived Risk” has a positive effect on “Attitude towards Green Products” and “Price Sensitivity”. “Attitude towards Green Products” has a positive effect on “green purchasing behavior” while “Price Sensitivity” has a negative effect on “green purchasing behavior”. This study focuses on existing literature by providing experimental evidence showing the importance of green consumption in the Iranian industry. The present model provides valuable input to policymakers and marketers to work from the perspective of policies and green marketing strategies and the research framework of purchasing green products to preserve the environment and the prevalence of green consumption among consumers.
Effect of Foliar Application of Nutrients on Yield and Nutrient Uptake by Rice Crop
Authors: Singh Nandan , Kumar Neeraj , Anshuman Kumar , Singh Ram Ratan , Yadav Sandeep , Singh Ankit
Published: October 2023

A field experiment was conducted during 2018 and 2019 at the Agronomy Research farm of A.N.D. University of Agriculture and Technology, Kumarganj, Ayodhya, UP to evaluate the effect of foliar application of macro and micronutrients on yield and nutrient uptake of rice (Oryza sativa L.). The experiment consists of 10 treatment combinations with some foliar application macro and micronutrients two foliar spray tillering stages and a panicle initiation stage which were laid out in randomized block design with three replications. The results revealed maximum grain yield (38.50 and 40.40 q ha-1), straw (51.90 and 54.60 q ha-1), and harvest index (42.64 and 42.53 %) with treatment T10-75% RDF + WSCF @ 0.5 % (19:19:19) + ZnSO4 @ 0.5 % + Boron @ 0.25 % which was statistically at par with T3- 125 % RDF and significantly superior over rest of the treatments during both the years ., was recorded Similarly significant improvement in nutrient uptake (N, P, K, S, Zn, and B) by rice was observed in T10. Thus, it can be concluded that the application of 75% RDF + WSCF @ 0.5 % (19:19:19) + ZnSO4 @ 0.5 % + Boron @ 0.25 % can improve the yield and nutrient uptake.
Factors Influencing the Knowledge Level of Farmers about Solar Pumps in Jodhpur District of Rajasthan, India
Authors: Choudhary Divya , Lal Banwari , Choudhary Kamlesh , Yadav Reshma
Published: October 2023

The research investigation was carried out in Rajasthan's Jodhpur district. In the Jodhpur district of Rajasthan, there are a total of seven tehsils. Osian and Balesar were chosen as the two tehsils with the most solar pumps installed. On the basis of who would benefit from solar pumps the most, ten villages from each chosen tehsil were selected. Twenty villages were chosen because they had the most solar pumps, and one hundred twenty-five (125) respondents were chosen from them. Age, caste, education level, size of land holding, family type, social participation, annual family income, occupation, extension contact, and mass utilization were identified as the significant variables that may have influenced the level of knowledge of farmers about solar pumps in the research that examined the social economic status of the respondents. This study revealed that although farmers' awareness of solar pumps was positively and strongly correlated with age, educational attainment, social engagement, occupation, extension contact, and media use. Family type, annual income, and size of land holding show positive and significant relationships with farmers' solar pumps knowledge levels, while caste indicates a negative and non-significant association.
Performance of Pigeonpea Varieties against Sterility Mosaic Disease (SMD) for Rainfed Regions of Prakasam District, Andhra Pradesh, India
Authors: Rajesh Chowdary L.  , Haritha P.  , Pramila Rani B.
Published: October 2023

Pigeonpea is one of India's most important grain legumes, accounting for 90 per cent of global production. It is primarily farmed and consumed in poor nations, with India being a major producer. The area under Red gram crop in Prakasam district is about 1,00,000 hectares, which is under Rainfed cultivation during Kharif season, as a sole crop. The occurrence of Sterility Mosaic Disease (SMD) has resulted in significant yield loss over the last three years in Prakasam District. As a result, the current study was done to investigate the performance of seven varieties for the disease incidence and yield attributes that are suitable for rainfed region of Prakasam district were evaluated. Among the varieties evaluated, no disease incidence was observed in BSMR 736 (842 kg/ha), ICPL87119 (816 kg/ha) followed by TRG 59 with disease incidence of 8.67 per cent and yield of 756 kg/ha. The variety GRG 152 recorded disease incidence of 4.47 per cent and yield of 610 kg/ha. The variety LRG 105 recorded disease incidence of 26.33 per cent and yield of 546 kg/ha which was found to be moderately resistant. These findings are important for choosing resistant genotypes and can be used to validate and generate more SMD resistant pigeonpea genotypes in the future.