bluuebunny/crossref_metadata_2025 huggingface dataset:
KONSEP MUDHARABAH DALAM SISTEM KEUANGAN ISLAM: ANALISIS FIQH DAN PRAKTIK PEMBIAYAAN
Authors: Badruddin  , Hasan Husaini
Published: January 2025

Mudharabah adalah salah satu bentuk kerjasama dalam ekonomi Islam, di mana pemilik modal (shahib al-mal) memberikan modal kepada pengelola (mudlarib) untuk dijalankan dalam usaha produktif. Keuntungan dari usaha tersebut dibagi berdasarkan kesepakatan, sementara kerugian sepenuhnya ditanggung oleh pemilik modal, kecuali jika ada kesalahan dari pengelola. Penelitian ini bertujuan untuk menganalisis konsep mudharabah dalam perspektif fiqih dan implementasinya dalam sistem keuangan syariah. Dengan menggunakan metode kualitatif dan pendekatan studi literatur, penelitian ini mengkaji berbagai sumber fiqih dan pendapat para ulama mengenai rukun, syarat, dan jenis mudharabah. Hasil penelitian menunjukkan bahwa mudharabah terdiri dari dua jenis, yaitu mudharabah mutlaqah yang bersifat fleksibel dan mudharabah muqayyadah yang lebih terikat pada spesifikasi usaha tertentu. Pembahasan ini juga menyoroti pentingnya kejelasan rukun dan syarat dalam akad mudharabah, yang mencakup modal, pekerjaan, dan keuntungan yang harus disepakati bersama. Implementasi mudharabah dalam sistem perbankan syariah dapat memberikan alternatif pembiayaan yang adil dan sesuai dengan prinsip-prinsip syariah, serta mendukung terciptanya keadilan ekonomi dalam masyarakat.
Peningkatan Kesejahteraan Masyarakat Kampung Bandar Sungai Melalui Program Digital Marketing Umkm
Authors: Ghalby Firansyah  , Ria Yolanda Br Sinaga  , Raja Silfiah Irwan  , Nurul Jihan Islami  , Nurma Syakira  , Nita Natalia Lumban Gaol  , Liza Sabilla Putri  , Kanaya Shalsabilla  , M. Muflih Imam Ardian  , R. Ahmad Baihaqi  , Naufal Dzaki Disnie  , Wan Laela Syafitri
Published: January 2025

Di era digital saat ini, kemudahan masyarakat untuk membuka usaha dan lapangan kerja yang baru sangat mudah dilakukan. Potensi tersebut bisa dimaksimalkan apabila pengetahuan dan pembekalan bagi para UMKM untuk membangun usahanya dari awal sehingga berhasil di kemudian waktu. Selain itu, sebagai pelaku bisnis pada usaha yang dijalankan, seorang wirausahawan/i yang menjalankan usaha di Usaha Mikro, Kecil dan Menengah (UMKM) perlu memiliki strategi pemasaran yang baik. Dalam upaya meningkatkan kesadaran masyarakat untuk mulai berwirausaha dan membangun usahanya menjadi lebih berkembang lebih baik, perlunya memberikan pengetahuan serta pemahaman mengenai strategi pemasaran dengan memanfaatkan teknologi digital, kuhususnya di masa pandemi Covid-19 ini. Oleh karena itu, webinar yang bertema “Strategi Membangun UMKM Kreatif dan Inovatif di Era Digital” menjadi kegiatan pengabdian kepada masyarakat yang dapat dilakukan. Webinar ini merupakan salah satu wadah dalam membangun kesadaran para pelaku bisnis UMKM mengenai strategi-strategi yang dapat dilakukan untuk dapat bertahan di tengah pandemi Covid-19 dengan memanfaatkan media sosial dan digital marketing dalam melaksanakan kegiatan bisnisnya.
Kajian Sosiologi Hukum Tentang Kepercayaan Masyarakat Terhadap Tuna Daksa Sebagai Pelaku Tindak Pidana Kekerasan Seksual (TPKS)
Authors: Anes Sefta Asmita
Published: January 2025

Munculnya Ketidakpercayaan masyarakat terhadap Tuna Daksa sebagai Pelaku Tindak pidana Kekerasan Seksual (TPKS) menjadi fenomena yang terjadi belakangan ini. Sebagian Besar Masyarakat tidak mempercayai bahwasannya Tuna Daksa atau orang dengan keterbatasan Fisik mampu melakukan Kekerasan Seksual. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang bisa merubah paradigma berfikir masyarakat terhadap pelaku tindak pidana yang memiliki keterbatasan fisik tetapi mampu melakukan tindak pidana layaknya orang normal pada umumnya, didukung fakta-fakta lapangan dan analisa penyebab fenomena terjadi berdasarkan pemberitaan yang beredar tentang Tindak Pidaan Kekerasan seksual yang dilakukan oleh tuna daksa. Penelitian ini menggunakan metode yuridis normatif dengan melalui studi kepustakaan yang dianalisis secara deskriptif. Kasus Tindak Pidana Kekerasan seksual yang terjadi belakangan ini adalah kasus-kasus kekerasan seksual yang dilakukan oleh seorang tuna daksa bernama I Wayan Agus Suartama atau yang disebut “Agus Buntung” yang memiliki keterbatasan fisik dengan keadaan fisik yang tidak memiliki kedua lengan tangan. Kasus Tindak Pidana kekerasan seksual yang dilakukan oleh tuna daksa adalah kasus pertama yang terjadi sehingga menyita perhatian masyarakat luas dan menimbulkan ketidakpercayaan publik. Kepercayaan publik terhadap kasus yang terjadi dapat dibangun jika masyarakat mengetahui asal muasal penyebab terjadinya tindak pidana kekerasan seksual tersebut tentunya disertai dengan fakta ilmiah ataupun logis sehingga keraguan masyarakat akan berkurang, tertutama jika kasus serupa terjadi dengan pelakunya adalah seorang tuna daksa.
The Pancreatic Hypermetabolic Lesions of Lung Carcinoma Patients in F-18-Fluorodeoxyglucose PET-CT: Correlation with Pathology
Authors: Yavan Gökçe , Koç Zehra Pınar , Özcan Pınar Pelin , Eser Kadir , Yaldız Mehmet
Published: January 2025

Aim: The ratio and results of the hypermetabolic lesions of the pancreas in lung carcinoma patients in FDG PET-CT which is rare, wasn’t sufficiently evaluated previously in the literature. The aim of this study was to determine these lesions’ pathologic correlations.
Materials and Methods: The F-18 FDG PET/CT images of the 516 patients with Lung Carcinoma was evaluated retrospectively by an Experienced Nuclear Medicine Physician and correlation of Pathology results were analyzed.
Results: The ratio of the pancreatic hypermetabolic lesions were 7% (36 patients). Pathology results revealed small cell lung carcinoma metastasis in 23, adenocarcinoma in 8, squamous cell carcinoma in 1 and atypical carcinoid tumor in 1 and other pathology types in rest of the patients in primary Lung Carcinoma. Five of the pancreatic lesions pathology results could be obtained and three were small cell lung carcinoma, one of them was adenocarcinoma and the squamous cell carcinoma in other one.
Conclusion: The hypermetabolic pancreatic lesions in Lung Carcinoma patients in F-18 FDG PET/CT should be evaluated and considered carefully. Since unexpected pathology results could be achieved.
Diagnostic and Prognostic Value of Serum Vitronectin and Galectin-3 levels in Thyroid Tumors
Authors: Arslan Esra , Alçın Göksel , Orhan Bağnu , Sönmez Derya , Can Trabulus F.didem , Sünter Ahmet Volkan , Ulusan Kıvılcım
Published: January 2025

Objective: Increased expression of Galectin-3(Gal-3) and Vitronectin (VN) molecules has been the subject of research, since it may be a biological marker that can be used for the separation of benign and malignant tissues. We aimed to evaluate serum Gal-3 and VN expression levels in the presence of thyroid tissue, and evaluate the predictive and prognostic value of these molecules in the differential diagnosis of malignant tissues.
Materials and Methods: 44 patients with thyroid nodules were included in this prospective study. Benign and malignant lesions were distinguished from thyroidectomy materials.
Results: Mean preoperative Gal-3 and VN values measured in malignant lesions were statistically significantly higher than preoperative Gal-3 and VN values in benign lesions (p-values: 0.007 and 0.009, respectively). Also, mean Gal-3 and VN values measured in serum were significantly reduced after operation compared to preoperative values (p-values
Rabaty stosowane przez przedsiębiorstwa dominujące w świetle orzecznictwa Trybunału Sprawiedliwości Unii Europejskiej w latach 2011–2015
Authors:   Wydział Prawa i Administracji Uniwersytetu Warszawskiego, Bułakowski Kamil
Published: January 2025

Niniejszy artykuł został poświęcony problematyce udzielania rabatów przez przedsiębiorstwa dominujące w świetle unijnego prawa konkurencji. Zagadnienie przedstawiono w świetle bardziej ekonomicznego podejścia (more economic approach) oraz w oparciu o wydane w latach 2011–2015 orzeczenia Trybunału Sprawiedliwości Unii Europejskiej – Tomra (2011), Intel (2014) oraz Post Danmark II (2015) oraz uwzględnia opublikowaną w październiku 2016 r. opinię Rzecznika Generalnego Nilsa Wahla.
Korytarze przesyłowe w ustawodawstwie Stanów Zjednoczonych Ameryki
Authors:   Wydział Prawa i Administracji Uniwersytetu Łódzkiego, Sokół Mateusz
Published: January 2025

Niniejszy artykuł obiera za przedmiot nieczęsto podejmowaną w polskiej literaturze problematykę korytarzy przesyłowych w Stanach Zjednoczonych Ameryki jako jeden z elementów mających zapewnić szeroko pojęte bezpieczeństwo energetyczne. Korytarz przesyłowy to wyodrębniony normatywnie teren, o specjalnym statusie prawnym, z istnieniem niekiedy zamanifestowanym w sposób faktyczny, na którym mają być albo już są posadowione urządzenia przesyłowe, obarczony specyficznymi funkcjami, definiującymi istotę korytarza. Autor wychodzi od rozważań nad kwestią dostępu przedsiębiorców przesyłowych do nieruchomości obarczonej urządzeniami przesyłowymi, następnie przechodzi do wskazania podziału na różne rodzaje korytarzy przesyłowych i dokonuje ich szczegółowego omówienia wraz z przedstawieniem refleksji nad ich wzajemnymi relacjami.
Cartographier l’altérité radicale : Shenzhen (2000) de Guy Delisle
Authors: Boucher François-Emmanuël
Published: January 2025

Cet article aborde la distance sous l’angle de l’altérité radicale en soulignant l’isolement du protagoniste dans la bande dessinée Shenzhen (2000) de Guy Delisle. Cette notion de distance informe l’esthétique du livre. Le personnage évolue à l’écart, séparé psychologiquement des milieux qu’il fréquente, incapable non pas tant de fusionner ou de communier avec l’autre, mais de communiquer le moindrement avec lui. Ainsi, il s’agit de lire la manière dont Guy Delisle participe au façonnement d’une nouvelle image de la Chine, désormais très différente de celle qui avait cours au moment de la Révolution tranquille au Québec.
Deux autrices franco-québécoises : itinéraires croisés de Julie Delporte et de Mirion Malle
Authors: Rannou Maël
Published: January 2025

Cet article aborde les oeuvres de Julie Delporte et de Mirion Malle, deux bédéistes franco-québécoises. Les portraits dressés dans cette étude portent attention à leurs parcours et à leurs oeuvres afin d’en examiner le rapport revendiqué ou perçu à l’identité québécoise. Pour ce faire, en sus de l’analyse des oeuvres et de divers articles et entretiens évoquant les artistes, deux entretiens longs ont été réalisés avec les autrices pour mettre l’accent sur la réception de leurs oeuvres et leur propre ressenti devant celle-ci.
PLANCHES, une revue de BD québécoise : entre dynamisme et précarité, 2014-2024
Authors: Reyns-Chikuma Chris
Published: January 2025

Mon but, dans cet article, est de présenter et analyser la revue PLANCHES, créée par Sandra Vilder et Émilie Dagenais en 2014. Dans la première partie, je donnerai quelques repères chronologiques qui ont jalonné l’histoire de cette revue, tout en situant son projet à la fois dans l’histoire de la bande dessinée québécoise (BDQ) et dans le marché francophone mondialisé des revues de bandes dessinées (dominé par celui de l’Europe francophone). Dans la deuxième partie, je ferai une étude systématique des dix-huit numéros de manière quantitative et qualitative pour révéler à la fois les structures, les idées et les tendances esthétiques de la revue, à l’aide de quelques tableaux sur la représentation des genres (gender) et des groupes culturels, linguistiques et ethniques et d’une analyse des catégories de BD (BD de reportage, BD humoristique, etc.). Je pourrai alors conclure mon texte en abordant la ligne éditoriale de PLANCHES et les raisons possibles de son succès et de sa précarité.
Formes contemporaines du strip québécois
Authors: Butch Nick
Published: January 2025

Dans cet article, nous nous sommes intéressés à la pratique contemporaine du strip au Québec à partir du travail de trois bédéistes qui sont toujours actifs : Daniel Shelton, Pascal Girard et Boum. Leurs productions des trente dernières années ont servi de corpus de recherche. Nous avons repéré trois pratiques du strip : formaliste, occasionnelle et numérique. Nous sommes arrivés à la conclusion que cette forme narrative commence à s’installer durablement dans le paysage de la bande dessinée québécoise, à la fois par le travail des bédéistes, par celui des autres acteurs culturels (éditeurs, enseignants), mais principalement par l’évolution des trois principaux supports de diffusion du strip : le journal, l’album et l’écran.
Polémique dans et sur La paix des femmes de Véronique Côté
Authors: Bastien Sophie
Published: January 2025

La pièce La paix des femmes de Véronique Côté, présentée au Théâtre La Bordée à Québec du 13 septembre au 8 octobre 2022, puis en webdiffusion pendant trois mois, traite de la marchandisation du corps de la femme. Ce sujet est tellement brûlant et polarisé que la pièce a suscité de vives réactions et laissé des traces profondes. Pour saisir ce phénomène multiforme, il importe d’exposer au préalable le contexte social qui a donné lieu à la création de la pièce, car il établit déjà la pertinence de celle-ci. J’examinerai ensuite le caractère polémique et féministe de son contenu. Puis j’étudierai les empreintes qu’ont laissées le texte dramatique et surtout sa réalisation scénique; je ferai ressortir les différentes natures de ces empreintes et leurs provenances variées qui déterminent leur portée idéologique. Enfin, je comparerai la pièce de Côté à ses antécédents culturels afin de montrer en quoi elle s’en démarque.
Le status epilepticus chez la personne adulte : le rôle essentiel du personnel
infirmier à l’urgence
Authors: Tessier William , Mileto Elisa , Blais Sabrina
Published: January 2025

Le status epilepticus (SE), aussi appelé état de mal épileptique, est une urgence
neurologique pouvant entraîner des lésions cérébrales permanentes et engager le pronostic
vital de la personne adulte à l’urgence. Son aspect critique, ses nombreuses causes
potentielles, ainsi que la présence d’étiologies sous-jacentes sont tous des facteurs à
l’origine d’une prise en charge complexe. Ainsi, cet article clinique a pour objectif de
mettre en évidence l’important rôle des personnes infirmières à l’urgence dans la prise en
charge rapide et sécuritaire de la personne adulte présentant un SE. Tout d’abord, un
portrait global du SE sera présenté. Puis, le processus physiopathologique du SE sera
décrit, permettant ainsi de mieux comprendre les manifestations cliniques chez la personne
soignée. Enfin, une revue des meilleures pratiques concernant la prise en charge du SE chez
la personne adulte à l’urgence sera présentée.
Simulation in situ adaptée au personnel infirmier en soins d’urgence d’un centre hospitalier rural : une recherche-action participative
Authors: Provost Josiane , Lavoie Stéphan , Ledoux Isabelle
Published: January 2025

Les urgences en milieu rural se caractérisent par une fréquence moins élevée de situations cliniques critiques, ce qui limite l’exposition du personnel infirmier à ces enjeux. De plus, l’accès au développement professionnel continu (DPC) est parfois restreint, ce qui compromet la mise à jour des compétences et diminue ainsi la sécurité des personnes soignées. Une recherche-action a été effectuée, avec pour objectif le développement et la mise en place d’une simulation in situ adaptée au personnel infirmier en soins d’urgence d’un centre hospitalier rural. Des méthodes de collecte de données inductives et déductives, telles que des observations sur le terrain et des groupes de discussion, ont été utilisées afin d’identifier les besoins de formation théorique et technique spécifiques de 11 infirmier.ères d’urgence. Une simulation in situ a été élaborée en collaboration avec le personnel infirmier, en suivant la méthode de la zone de simulation de Roussin et Weinstock (2017) et la théorie de la simulation de Jeffries (2021). En conclusion, la simulation in situ a répondu à la plupart des exigences en matière de DPC pour le personnel infirmier de cette urgence rurale, en plus de favoriser l’accès à l’apprentissage expérientiel.
La pratique infirmière en transport héliporté au Québec
Authors: Severino Fabian
Published: January 2025

Le transport médical héliporté (TMH) au Québec fait l’objet de discussion depuis plus de 20 ans, mais la province demeure la seule au Canada sans service public de TMH. Malgré cette absence, certaines compagnies privées opèrent déjà depuis plusieurs années dans ce domaine, contribuant au développement d’une pratique infirmière spécifique au TMH. Cet article a pour objectif de présenter cette pratique infirmière encore peu répandue au Québec, à travers la perspective de l’auteur, ayant près de deux ans d’expérience dans le domaine.
Disruption of the CRF1 receptor eliminates morphine-induced sociability deficits and firing of oxytocinergic neurons in male mice
Authors: Piccin Alessandro , Allain Anne-Emilie , Baufreton Jérôme , Bertrand Sandrine S , Contarino Angelo
Published: January 2025

Substance-induced social behavior deficits dramatically worsen the clinical outcome of substance use disorders; yet, the underlying mechanisms remain poorly understood. Herein, we investigated the role for the corticotropin-releasing factor receptor 1 (CRF
1
) in the acute sociability deficits induced by morphine and the related activity of oxytocin (OXY)-and arginine-vasopressin (AVP)-expressing neurons of the paraventricular nucleus of the hypothalamus (PVN). For this purpose, we used both the CRF
1
receptor-preferring antagonist compound antalarmin and the genetic mouse model of CRF
1
receptor-deficiency. Antalarmin completely abolished sociability deficits induced by morphine in male, but not in female, C57BL/6J mice. Accordingly, genetic CRF
1
receptor-deficiency eliminated morphine-induced sociability deficits in male mice.
Ex vivo
electrophysiology studies showed that antalarmin also eliminated morphine-induced firing of PVN neurons in male, but not in female, C57BL/6J mice. Likewise, genetic CRF
1
receptor-deficiency reduced morphine-induced firing of PVN neurons in a CRF
1
gene expression-dependent manner. The electrophysiology results consistently mirrored the behavioral results, indicating a link between morphine-induced PVN activity and sociability deficits. Interestingly, in male mice antalarmin abolished morphine-induced firing in neurons co-expressing OXY and AVP, but not in neurons expressing only AVP. In contrast, in female mice antalarmin did not affect morphine-induced firing of neurons co-expressing OXY and AVP or only OXY, indicating a selective sex-specific role for the CRF
1
receptor in opiate-induced PVN OXY activity. The present findings demonstrate a major, sex-linked, role for the CRF
1
receptor in sociability deficits and related brain alterations induced by morphine, suggesting new therapeutic strategy for opiate use disorders.
A New Role for RNA G-quadruplexes in Aging and Alzheimer’s Disease
Authors: Kallweit Lena , Hamlett Eric D , Saternos Hannah , Gilmore Anah , Granholm Ann-Charlotte , Horowitz Scott
Published: January 2025

As the world population ages, new molecular targets in aging and Alzheimer’s Disease (AD) are needed to combat the expected influx of new AD cases. Until now, the role of RNA structure in aging and neurodegeneration has largely remained unexplored. METHODS: In this study, we examined human hippocampal
postmortem
tissue for the formation of RNA G-quadruplexes (rG4s) in aging and AD.We found that rG4 immunostaining strongly increased in the hippocampus with both age and with AD severity. We further found that neurons with accumulation of phospho-tau immunostaining contained rG4s, that rG4 structure can drive tau aggregation, and that rG4 staining density depended on APOE genotype in the human tissue examined.Combined with previous studies showing the dependence of rG4 structure on stress and the extreme power of rG4s at oligomerizing proteins, we propose a model of neurodegeneration in which chronic rG4 formation drives proteostasis collapse. These morphological findings suggest that further investigation of RNA structure in neurodegeneration is a critical avenue for future treatments and diagnoses.
Machine Learning-Based Techniques for Assessing Critical Factors for European Tick Abundance
Authors: Lansdell Samantha , Sharif Mhd Saeed , Zorto Abin , Seto Misaki , Negera Edessa , Cutler Sally
Published: January 2025

Tick-borne diseases are a significant health risk to humans and animals worldwide. It is important to understand the environmental and climatic factors that contribute to tick occurrence rates in order to reduce the proliferation of tick-borne diseases. Using machine learning and spatial indexing techniques, this study covers tick occurrence rates in Europe over the last 20 years to understand the environmental and climatic factors that contribute to Ixodes ricinus tick abundance. We used biodiversity databases to study land cover categories, climate, vegetation index, and sociological factors. Areas with agriculture and natural vegetation, especially broad-leaved forests, had the strongest tick correlation. Waterways and pastures also showed significant positive correlations, indicating tick habitats. Ticks have moderate associations with urban green spaces, industrial units, and mixed forests suggesting their presence in ecologically disturbed habitats. Geoclimatic factors namely Normalised Difference Vegetation Index and rainfall, showed weak to negative correlations with tick population, indicating that they were less important than previously assumed. Linear Regression, Decision Tree, Random Forest, and Support Vector Machine were compared. We found that feature set and outlier presence significantly affected model performance. After removing outliers, Linear Regression performed best for land use features, with an R² value of 0.81, Normalised Root Mean Square Error (NRMSE) of 1.56, Scatter Index (SI) of 1.56, and Mean Absolute Percentage Error (MAPE) of 1.22. Outlier exclusion improved the model performance results. This research emphasises the importance of specific land uses in predicting the dynamics of tick populations. Our findings lay the groundwork for focused intervention strategies to reduce the spread of tick-borne diseases using an innovative and intelligent approach, while also emphasising the need for further investigation into the complex interactions between environmental factors and tick abundance.
Finite Element Analysis of Temperature Effects on Underground Large-Diameter Concrete Cylinders Using ABAQUS
Authors: Chen Fuzheng
Published: January 2025

With the increasing demand for storage capacity, the diameter of silos has also been continuously increased. For this kind of large-diameter concrete cylinder, the temperature load has a great influence, especially the cylinder structure located underground, and the stress characteristics are more complicated under the influence of earth pressure and gradient temperature. This study investigates the stress distribution and deformation in underground large-diameter concrete cylinders under temperature loads using finite element analysis with ABAQUS. By simulating temperature changes through boundary conditions, the research identifies critical stress patterns, particularly the significant hoop tensile stress observed during temperature decreases, which peaks at 2.75 MPa. These findings emphasize the need for enhanced tensile capacity in specific regions of the structure. The results provide valuable insights for optimizing the design and ensuring the structural integrity of underground concrete cylinders under varying thermal conditions.
Bioaccumulation of Mercury and Its Consequences on Biochemical Parameters in Coriander (Coriandrum sativum) Plants
Authors: Mani Vijay , Krishnan BuvaneshKumar , Govindaraj Devaganesh , Nagappan Sivapragasam
Published: January 2025

Mercury is a highly toxic heavy metal that poses severe environmental and ecological issues due to its ability to bioaccumulate in various ecosystems. It persists in the environment and is known to have serious effects on both plants and animals. This study investigates the bioaccumulation of Mercury and its consequences on biochemical parameters in Coriander (Coriandrum Sativum) plants. The experimental design involved four groups, with Group 1 serving as the control, received no mercury treatment, while Groups 2, 3, and 4 were subjected to mercury concentrations of 50, 100, and 200 mg respectively. These varying concentrations of mercury allowed for a detailed examination of the dose dependent effects of mercury exposure on plant growth and metabolic functions. The results demonstrated that mercury treatment caused a marked decline in crucial growth parameters, including germination percentage, root length, shoot length, fresh weight, dry weight and vigor index, all of which were significantly lower in the treated groups compared to the control plants, indicating that contamination of mercury hindered the overall growth and development of the plants. Biochemical analysis revealed that mercury exposure disrupted various metabolic processes, leading to oxidative stress and an imbalance in reactive oxygen species (ROS). Increased mercury concentrations were associated with a significant reduction in carbohydrate metabolism and protein synthesis, reflecting impairments in energy metabolism and overall physiological functions. The reduction in protein content was linked to enzyme inhibition, compromising protein synthesis pathways essential for cellular functions and stress tolerance. These findings highlight the phytotoxic effects of mercury and its detrimental effects on plant physiology, ultimately limiting growth potential and photosynthetic efficiency. This research contributes valuable insights into the ecotoxicological impacts of mercury contamination in plants and underscores the potential of plant-based phytoremediation strategies for mitigating heavy metal pollution in contaminated soils.
Histopathological Effect of Aqua Fix Supplementation on the Skeletal Muscle and Liver of Labeo rohita (Hamilton,1822) during Immunomodulation and Aeromoniasis
Authors: N. Ankamma, , V. Viveka Vardhani,
Published: January 2025

The impact of oral feeding diet (supplement) Aqua Fix was studied on the histopathological changes in skeletal muscles and liver of L.rohita during  immunomodulation and aeromoniasis. Three groups (D,E,F) of six months old fish were employed; groups D and E were treated with Aqua Fix  for 4 days, on day 5 fish of group E and F were infected with Aeromonas hydrophila @ 10-6CFU/fish(fish of  group F were fed with normal diet for 4 days).Controls (group G) were untreated and uninfected. Histological examination of the skeletal muscle and liver tissues were carried out on selected days of experimentation (day 1 and day 4 of experiment). The stained sections were observed under microscope and histological changes were noted. Immunostimulated fish (group D) showed normal arrangement of muscle fibers and muscle bundles compared to other groups (E and F) of fish.  Both the muscle fibers and muscle bundles were healthy as in controls (Group G). In infected group (untreated with Aqua Fix, group F), fragmentation of muscle fibers was noticed along with sarcoplasmic debris.  Dermal lesions and moderate edema is noticed in necrotic muscle fibers. Liver in immunostimulated fish showed large, polygonal hepatocytes with distinct, round nuclei. Hepatic central vein and sinusoids were clearly visible. By day 1 of infection, liver exhibited necrosis of hepatocytes, pycnosis of hepatocyte nuclei, granulation and vacuolisation (group F).  Dilation of hepatic vein and sinusoids were observed.  Necrotic foci and haemorrhages were evident in the capillaries of liver and occurred more severely in group F compared to group E (treated with Aqua Fix and infected). The fish (group E) which received immunostimulant and infection showed moderate effect on liver suggesting that Aqua Fix supplementation ameliorate the ill effects of A. hydrophila, showing the positive influence of    herbal immunostiomulant i.e, Aqua Fix in fresh water fish.
Plasma Lipid Lowering Potential of Carrot (Daucus carota) Extract in Male Wistar Rats
Authors: Obia Onyebuchi , Kalio Regina Oripirisiki , Tee Popnen Godwin Porobe , Onyeso Godspower
Published: January 2025

Carrots (Daucus carota) are widely consumed for their nutritional and medicinal benefits. The aim of the present study was to investigate the effects of Daucus carota on lipid profile. The study involved 28 male wistar rats separated into 4 groups of 7 rats each. Group 1 served as control and was given distilled water, whilst groups 2, 3 and 4 served as test groups and were given aqueous extract of Daucus carota at daily doses of 200mg/kg, 400mg/kg and 600mg/kg respectively. The experiment lasted for 28 days and thereafter, blood samples collected for determination of lipid profile [total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL) and low density lipoprotein (LDL)] using standard laboratory techniques. Results showed that oral administration of all three doses of carrot extracts significantly reduced the plasma concentrations of both TC and TG but caused no significant changes in the LDL levels. However, the higher doses; 400mg/kg and 600mg/kg significantly increased the HDL levels in wistar rats. The lipid lowering potential of Daucus carota could be based on its fibre content as well as its antioxidant content which possibly enhanced fecal excretion of lipids. Conclusively, moderate consumption of Daucus carota decreased the plasma levels of TC and TG, increased HDL but had no significant effect on the LDL.
Exploring the Potential of Pearl Millet for Eco-friendly Sugar Syrup Production
Authors: VP Aparnna , Roy Kuntal
Published: January 2025

Pearl millet is a widely cultivated crop that finds its way into a variety of cuisines around the globe. It is esteemed for its nutritional advantages, highlighting the importance of large-scale processing. It stands out as a sustainable and eco-friendly crop, demonstrating remarkable adaptability in both arid and rainfed areas. Its high productivity coupled with minimal water needs positions it as a significant contributor to addressing food insecurity and poverty challenges. This review highlights the significance of pearl millet as a promising source for the production of glucose, malt, and sugar syrup. The advancements in the sugar extraction process, focusing on techniques such as enzymatic hydrolysis and the application of hydraulic press mechanization has been examined. The implementation of strategies aimed at enhancing sugar-syrup production from PM presents a promising opportunity to decrease dependence on traditional sugar production methods, which typically require significant inputs from high-input crops.
Association between Helicobacter pylori Infection and Iron Deficiency in Sudanese Population in Khartoum State
Authors: Mohammed Amged Ameen , Elmukashfi Salman Taha Ahmed , Ali Mohammed Abdalsalam Ahmed , Altayeb Hisham Nour Aldayem , Aloob Husham M taha , Arman Amira. H.
Published: January 2025

Background: Helicobacter pylori infection is a major gastric infection worldwide and has been associated with many gastrointestinal and non-gastrointestinal diseases including hematological disorders.
Objective: Aimed to study the association between H. pylori infection and iron deficiency among Sudanese population.
Materials and Methods: This is analytical case control study, conducted in Sudan, Khartoum state in Omdurman locality, during the period from May 2018 to April 2019. Include 100 samples, the stool and blood samples were collected from 100 Sudanese subjects (50 were infected with H. pylori as cases and 50 were apparently healthy subjects as controls). Stool samples were tested for H. pylori Ag by commercially available kits (HanzouAllTest Biotech Co., Ltd, Germany), all blood samples were analyzed for complete blood count using (SYSMEX KX21N) automated analyzer and serum iron profile (iron, ferritin, and TIBC) using spectrophotometery and turbidimetry. The obtained results is analyzed by SPSS versions 16.0, significant level was set at p-value equal or less than 0.05 and the results were presented in form of tables and figures.
Results: The results of H. pylori antigen were positive in all cases and negative in control samples. Serum iron level mean was significantly lower among H. pylori positive patient (62±18.1) than control group (91.3±16.7) (p-value 0.001), serum ferritin level mean was significantly lower in H. pylori infected patients (36.8±16.5) than control group (64±16.4) (p-value 0.003), hemoglobin level mean was significantly lower in H. pylori patients (12.5 ±1.1) than control group (13.8±1.0) (p-value 0.009), PCV level mean was lower in H. pylori patients (37.6±3.1) than control group (41±3.0) (p-value .036), TIBC mean was 313 in cases and 308 in control samples. All other parameters showed no significant difference between H. pylori positive patients and control subjects.
Conclusion: This study concluded that H. pylori infection is lead to iron deficiency in Sudanese patients.
Growth and Yield of Sweet Corn as Influenced by Nitrogen Levels and Crop Geometry
Authors: Pachoriya Deepak Singh , Kawade A.A , Panchal V. V.
Published: January 2025

An experiment was conducted during rabi, 2023 at new experimental cum demonstration field, Shri Vaishnav Institute of Agriculture, Shri Vaishnav Vidyapeeth Vishwavidyalaya, Indore. The field experiment was laid out in a split plot design with three replication. The main plot treatment comprised of three crop geometry viz., 60 cm x 20 cm (S1), 60 cm x 30 cm (S2), 60 cm x 40 cm (S3) whereas, sub plot treatments comprised of four nitrogen levels viz., 125: 60: 40 kg ha-1 (N1), 100: 60: 40 kg ha-1 (N2), 75: 60: 40 kg ha-1 (N3) and control (N4). The main objective of research was to study the effect of nitrogen levels and crop geometry on growth and yield of sweet corn. The crop geometry of 60 cm x 20 cm along with application of 125 per cent RDN has shown noticeably greater growth and yield parameters such as., plant height at harvest, days to 50% flowering, green cob yield, green fodder yield, biological yield and harvest index.
While, the crop geometry of 60 cm x 40 cm along with application of 125 per cent RDN has shown noticeably greater growth qualities such as., number of leaves at harvest, leaf area at harvest, dry matter at flowering and at harvest, yield attributing cob length with husk and without husk, cob diameter with husk and without husk, cob weight with husk and without husk, number of grains and grain weight cob‑1. Control treatment took maximum days to days to 50 per cent tasselling and 50 per cent silking.
Screening of Horsegram Genotypes for Resistance against Yellow Mosaic Disease
Authors: Pinjar Sonam R , G U Prema , Balol Gurupad , Nayak Spurthi N , Biradar Revanappa , Kandakoor Subhash , Wadeyar Bangaramma
Published: January 2025

Aims: The present study aimed to evaluate the screening of horsegram genotypes for resistance to yellow mosaic disease. The disease causes decrease in number of seeds per pods, number of pods per plant. The disease may occur at any phase of plant development.
Background: Horsegram crop suffers from yellow mosaic, powdery mildew, anthracnose, dry root rot, leaf spot, rust and cottony stem rot. Yellow Mosaic Disease (YMD) is recognized as the most detrimental viral affliction among the array of diseases induced by the Yellow Mosaic Virus. The occurrence of YMD in pulse crops has resulted in significant yield reductions, which can vary between 50 to 100 per cent. The best method to overcome YMD is the development of disease resistant varieties. Henceforth, an effort has been made to evaluate horsegram genotypes to obtain sources of resistance against YMD.
Place and Duration of Study: Field experiment for screening was conducted at Main Agricultural Research Station, University of Agricultural Sciences, Dharwad, Karnataka, India, during summer 2023-24.
Methodology: For screening, 148 genotypes were screened under natural epiphytotic conditions. Each genotype was sown in a 2 m row to test the resistance or susceptible reactions against YMD. A susceptible check (BGM-1) was planted after every 10 lines of test genotypes and all along the four sides of the field (infector row technique).
Results: Out of 148 genotypes evaluated, none of them were immune or resistant, 12 were moderately resistant, 47 were moderately susceptible, 46 were susceptible and remaining 43 genotypes showed highly susceptible reaction.
Conclusion: Identified moderately resistant genotypes can be utilized in YMD resistance breeding programme to develop YMD resistant varieties.
The Evaluation of Biochemical Parameters in Positive COVID-19 RealTime PCR Patients: A Retrospective Study
Authors: Bamahel Abdulaziz S. , Al-Kamel Haithm , Albaiti Ali M. , Bazomeh Nader F. , Zubair Nadeem
Published: January 2025

Coronavirus, a member of the beta coronavirus family, encompasses a range of illnesses from common colds to severe disorders. SARS-CoV-2, transmitted mainly through respiratory droplets that are generated by a patient who is sneezing, coughing and talking, caused the global pandemic COVID-19 in 2020. The virus primarily targets the respiratory system especially in the lung cell, leading to diverse symptoms and severe consequences. This study was carried out in the COVID-19 Isolation Centre in Mukalla City, Yemen, to evaluate biochemical tests in COVID-19 patients. In the retrospective single-centre study on 116 COVID-19 patients, some of biochemical Analysed Parameters were glucose, Liver function tests, renal function tests, lipid profile, and proinflammatory markers; convenience sampling based on existing records for socio-demographics, medical history, and biochemistry were analysed by using a spectrophotometry and Chemiluminescent immunoassay analyser. used SPSS version 25 to analyse data. Most COVID-19 patients in Mukalla City (91.4 % of those over 46 years old) have common symptoms such as fever, cough, and respiratory problems. The study found links between chronic health disorders (hypertension 96.6 %, diabetes mellitus 94.8 %) and greater vulnerability to COVID-19. Blood glucose levels substantially impact COVID-19 occurrences (p 0.0001). Some liver function tests are associated with COVID-19 (total protein, albumin, LDH, and GGT) (p = 0.044, 0.010, 0.0001, and 0.0001, respectively). Urea and creatinine levels imply renal function and their significant association (p=0.001 for both), whereas uric acid had no significant association with COVID-19 (p = 0.134). However, lipid profile tests lack statistical significance; they do identify trends. Proinflammatory markers CRP and ferritin strongly correlate with positive COVID-19 patients (p=0.0001 for both). In conclusion, COVID-19 significantly affects glucose metabolism, liver function, renal dynamics, and inflammatory markers, necessitating vigilant monitoring for clinical care and informing future research.
Population structure, serotype distribution and antibiotic resistance of Streptococcus pneumoniae causing invasive disease in Victoria, Australia
Authors: Higgs Charlie , Kumar Lamali Sadeesh , Stevens Kerrie , Strachan Janet , Sherry Norelle L. , Horan Kristy , Zhang Josh , Stinear Timothy P. , Howden Benjamin P. , Gorrie Claire L.
Published: July 2023

Streptococcus pneumoniae

is a major human pathogen and can cause a range of conditions from asymptomatic colonization to invasive pneumococcal disease (IPD). The epidemiology and distribution of IPD-causing serotypes in Australia has undergone large changes following the introduction of the 7-valent pneumococcal conjugate vaccine (PCV) in 2005 and the 13-valent PCV in 2011. In this study, to provide a contemporary understanding of the IPD causing population in Victoria, Australia, we aimed to examine the population structure and prevalence of antimicrobial resistance using whole-genome sequencing and comprehensive antimicrobial susceptibility data of 1288 isolates collected between 2018 and 2022. We observed high diversity among the isolates with 52 serotypes, 203 sequence types (STs) and 70 Global Pneumococcal Sequencing Project Clusters (GPSCs) identified. Serotypes contained in the 13v-PCV represented 35.3 % (n=405) of isolates. Antimicrobial resistance (AMR) to at least one antibiotic was identified in 23.8 % (n=358) of isolates with penicillin resistance the most prevalent (20.3 %, n=261 using meningitis breakpoints and 5.1 % n=65 using oral breakpoints). Of the AMR isolates, 28 % (n=101) were multidrug resistant (MDR) (resistant to three or more drug classes). Vaccination status of cases was determined for a subset of isolates with 34 cases classified as vaccine failure events (fully vaccinated IPD cases of vaccine serotype). However, no phylogenetic association with failure events was observed. Within the highly diverse IPD population, we identified six high-risk sub-populations of public health concern characterized by high prevalence, high rates of AMR and MDR, or serotype inclusion in vaccines. High-risk serotypes included serotypes 3, 19F, 19A, 14, 11A, 15A and serofamily 23. In addition, we present our data validating seroBA for in silico serotyping to facilitate ISO-accreditation of this test in routine use in a public health reference laboratory and have made this data set available. This study provides insights into the population dynamics, highlights non-vaccine serotypes of concern that are highly resistant, and provides a genomic framework for the ongoing surveillance of IPD in Australia which can inform next-generation IPD prevention strategies.
Progressive Familial Intrahepatic Cholestasis: A Descriptive Study in a Tertiary Care Center
Authors: Alsohaibani Fahad I. , Peedikayil Musthafa C. , Alfadley Abdulaziz F. , Aboueissa Mohamed K. , Abaalkhail Faisal A. , Alqahtani Saleh A.
Published: July 2023

Background. Progressive familial intrahepatic cholestasis (PFIC) is a rare genetic disorder that results from defective mechanisms of bile secretion. We aim to describe different types of PFIC and their clinical features, treatment modalities, and outcomes in Saudi Arabia. Patients and Methods. This is a retrospective study of all patients diagnosed with PFIC at King Faisal Specialist Hospital and Research Center in Riyadh from January 1, 2002, to December 31, 2021. All relevant information was collected from patient charts and transferred into the REDcap® database for statistical analysis. Results. A total of 79 patients were identified with PFIC, and PFIC type 3 was the most common (59.5%), followed by PFIC type 2 (34.2%), PFIC type 1 (5.1%), and PFIC type 4 (1.3%). Males and females were affected in 54.4% and 45.6%, respectively. Mutations in ATP8B1, ABCB11, and ABCB4 genes were observed in PFIC type 1, PFIC type 2, and PFIC type 3, and loss of function in a variant of TJP2 was detected in PFIC type 4, respectively. A total of 51 (64.6%) patients underwent liver transplantation: three patients (3/4) with PFIC type 1 (75%), twenty patients (20/27) with PFIC type 2 (74.1%), twenty-seven patients (27/47) with PFIC type 3 (57.4%), and one patient with PFIC type 4 (100%). The mean duration of disease before transplantation was

53.9
±
67

months with a median of 30 months. Following liver transplantation, symptomatic control was achieved in 47 patients (92.2%). Recurrence after transplantation occurred in 4 patients (7.8%) within an average of 22.5 months and a median of 17 months. Conclusion. PFIC is considered a rare disorder in Saudi Arabia; however, early recognition of the disease is important for appropriate management and early referral for liver transplantation evaluation. The overall rate of liver transplantation in our cohort was 64.6% with an excellent five-year survival rate.
A Diaminomaleonitrile based Schiff Base Colorimetric Sensor for Copper detection using smartphone-assisted RGB and Test kit Methods
Authors: Raju V. , K Imran.
Published: July 2023

A high selective and sensitive detection of Cu2+ in the semi-aqueous
phase by the naked eye has always been a challenge. In this paper, a
simple compound based on diaminomaleonitrile Schiff base probe (L) was
synthesized and its structure was confirmed by 1H, 13C NMR, FTIR, and
mass analysis. The probe L showed distinct colorimetric upon interaction
with Cu2+ in DMSO:H2O (5:5, v/v) media. The probe L exhibited a key
absorption peak at 374 nm due to π→π* transitions of the free probe,
upon the interaction with Cu2+ it shifted to 462 nm, which is due to the
LMCT mechanism. The probe L binds Cu2+ in a 1:1 ratio with an
association constant of (Ka) = 5.02×104 M-1 and this is established by
using the Job’s and Benasi-Hilderbrand (BH) methods. The detection limit
for Cu2+ can reach a concentration of as low as 0.705 μM with high
selectivity, even in a solution containing diverse metal ions. Besides,
the selective color change of L with Cu2+ was integrated with a
smartphone to monitor the change in the RGB tool and test paper kit. The
binding mechanism of L with Cu2+ was studied by using ESI mass and DFT
analysis.
TRAGEDI TERBUNUHNYA KHALIFAH ‘UTSMAN IBN ‘AFFAN
Authors: Arif Muhammad
Published: July 2023

AbstrakPembunuhan terhadap Utsman ibn Affan dianggap sebagai awal mula perpecahan umat Islam. Sebagian kalangan bahkan menuduh bahwa Utsman adalah salah satu aktor dalam kekacauan tersebut. dari beberapa literatur yang didapatkan, banyak sekali yang menunjukkan bahwa Utsman adalah korban dari tragedi tersebut. Tulisan ini merupakan salah satu upaya untuk mencoba memaparkan peristiwa tragis terbut dengan memilah berita-berita yang sudah teruji kebenarannya. Semua data yang ada akan diolah dan direkonstruksi sebagaimana mestinya. Tulisan ini menunjukkan bahwa tuduhan buruk yang selama ini dituduhkan kepada Utsman merupakan tuduhan yang tanpa bukti. Tuduhan tersebut justeru muncul karena kesalahfahaman terhadap beberapa kebijakan Utsman.
CARRYING OUT THE DEMOLITION OF A CAPITAL CONSTRUCTION OBJECT: LEGAL REGULATION AND SOME FEATURES
Authors: Жуков Ф.Ф.
Published: July 2023

Объектом исследования выступают нормы гражданского права и градостроительного права о сносе объектов капитального строительства. Целью работы является выявление гражданско-правовых и публичноправовых особенностей института сноса, которые отграничивают его от договора строительного подряда. Обосновывается необходимость введения института сноса в Гражданский кодекс Российской Федерации. Сформулирована позиция автора о наличии у сноса своих юридических особенностей, отграничивающих его от строительного подряда.

The object of the study is the norms of the civil law and the town planning law on the demolition of construction projects. The purpose of the work is to identify the civil law and public law features of the institution of demolition, which delimit it from a construction contract. There is substantiated the necessity of introducing the institution of demolition into the Civil Code of the Russian Federation. There is formulated the author's position that the demolition has its own legal features that delimit it from the construction contract.