bluuebunny/crossref_metadata_2025 huggingface dataset:
MEASURING THE AGRICULTURAL TOTAL FACTOR PRODUCTIVITY OF PROVINCES IN TURKEY USING MALMQUIST INDEX
Authors: Yaman Habibe , Sungur Onur , Dulupçu Murat Ali
Published: April 2024

This study aims to reveal the total factor productivity levels in the agricultural sector in 81 provinces of Turkey by using the Malmquist index method over the period 2009-2019. The results extracted from the Malmquist index findings show that index value changed between 1.186 and 0.952, agricultural productivity increased in 75 provinces and decreased in 6 provinces. In addition, our findings confirm technological change affects the change in agricultural productivity levels in all provinces in Turkey, and that technology is a determining factor in agricultural productivity in all provinces. From a policy perspective, the results suggest that authorities in Turkey should develop and implement technologies that will make the sector productive, to encourage and support infrastructure, research and publication studies on technology. In addition, this research claims that the regional incentive system can be revised and, it can build an incentive system based on performance and efficiency in which provinces or businesses operating in this field are classified according to their productivity.
MUHASEBE MESLEK MENSUPLARININ İŞ YAŞAM DENGESİNİN İŞ VE YAŞAM TATMİNLERİ ÜZERİNDEKİ ETKİSİ: TR72 BÖLGESİNDE BİR ARAŞTIRMA
Authors: Saraç Hakan , Onocak Derya
Published: April 2024

Günümüzde işgücü piyasalarında yaşanan değişimler ve rekabetin artması iş yaşam dengesinin sağlanmasını zorlaştırmaktadır. Çalışanların iş yaşam dengesini sağlayamamaları iş ve yaşam tatminsizliğini beraberinde getirmektedir. Bu çalışmada muhasebe meslek mensuplarının iş yaşam dengesi, iş ve yaşam tatmini analiz edilerek aralarındaki ilişki ve etki durumunun belirlenmesi amaçlanmıştır. Çalışmaya TR72 bölgesinde faaliyet gösteren 183 muhasebe meslek mensubu katılmıştır. Veriler analiz edilirken ilişkiyi belirlemek için korelasyon analizi ve etkiyi belirlemek için regresyon analizi yapılmıştır. Korelasyon analizi sonucunda iş tatmini ile yaşam tatmini arasında pozitif yönlü güçlü bir ilişki olduğu, işin yaşama olumsuz etkisi ile yaşamın işe olumsuz etkisi arasında pozitif yönlü ve orta düzeyde ilişki bulunmuştur. Regresyon analizi sonucunda işin yaşama olumsuz etkisinin yaşam tatmini üzerinde anlamlı etkisinin olduğu tespit edilmiştir. İşin yaşama olumsuz etkisi arttıkça yaşam tatminlerinin azaldığı sonucuna ulaşılmıştır
DOES E-GOVERNMENT FOSTER WELFARE? AN EMPIRICAL INVESTIGATION FOR DEVELOPING COUNTRIES
Authors: Yıldırım Abdulmecit , Almalı Vedat
Published: April 2024

In this study, the effect of e-government on welfare is examined using ordinary least squares estimations for developing countries. A cross-sectional data set was created by averaging the data available between 2003 and 2020. The study basically examines the transmission channels through which e-government affects welfare. These channels serve as crucial pathways that link e-government initiatives to welfare outcomes. By examining these channels, the study seeks to unravel the significance of e-government as a determinant of welfare. When the transmission channels are considered, e-government is an essential variable that explains welfare. According to the findings of the study, the most important channel through which e-government affects welfare is regulatory quality, which accounts for about 15% of the total impact. Furthermore, the study identifies corruption and political stability as additional channels through which e-government influences welfare. These channels, although accounting for a relatively smaller proportion of the total impact, still play significant roles in shaping welfare outcomes. Overall, the findings emphasize the multi-dimensional nature of e-government's impact on welfare. By considering various transmission channels, this study provides valuable insights into the mechanisms through which e-government initiatives can effectively improve overall welfare in developing countries.
Adhesive Resin Cementation of Posterior Hybrid-type Retainer Porcelain Fused to Metal Fixed Dental Prostheses
Authors: Waskitho Arief
Published: April 2024

Porcelain fused to metal (PFM) of fixed dental prostheses (FDP) remains the gold standard for rehabilitating partial edentulous. However, conventional PFM FDP requires lengthy procedures to achieve optimum retention, resistance, and esthetics, such as the geometry and depth of preparation. Adhesive technology could minimize the complexity of cementation to achieve retention and resistance by minimizing the preparation area, thus ruling out the geometry of preparation consideration. The optimal geometry of preparation is achieved by the preparation of a tooth structure with significant depth and geometry. Thus, abandoned preparation geometry increases the use of minimally invasive prosthodontics. Minimally invasive prosthodontics could minimize the possibility of future endodontic treatment. One option for treating partially edentulous patients with a minimally invasive approach is the hybrid PFM FDP, consisting of an inlay-bonded retainer with the vital tooth in one of the abutments and a conventional retainer with the non-vital tooth in the other. As a result, this report showed the reasoning and technology for cementation of hybrid-type retainer PFM FDP using adhesive technology in the posterior area. Findings uncovered that using adhesive technology, the cementation FRC FDP of hybrid-type retainer PFM FDP could minimize the preparation and cementation procedure without compromising retention and resistance. Therefore, future usage of hybrid-type retainer PFM FDP should be encouraged from a minimally invasive point of view
Management of Xerostomia and Hyposalivation in Hypertensive Patient's Using Candesartan Cilexetil
Authors: Wandhila Shely , Suhartiningtyas Dwi
Published: April 2024

Saliva’s disorder and dry mouth (xerostomia) are related to routine medication as antihypertensives. Candrsartan cilexetil is an angiotensin receptor blocker (ARB) hypertension drug that indirectly affects saliva by changing fluid and electrolyte balance. To examine the management of xerostomia and hyposalivation in hypertensive patients due to use of candesartan cilexetil. A 70 year old female patient complained her mouth felt dry since 1 year ago when she was diagnosed with hypertension. The patient consumes candesartan cilexetil once daily, 8 mg. Intra oral showed were edentulous areas on the entire upper and lower jaw with the patient's oral mucosa being dry, saliva thick, sticky and frothy. In this case, saliva’s rate measurement showed a result of 0.16 mL/minute. After intervention using dry mouth gel for two weeks, a saliva rate of 0.38 mL/minute. During the control, patient didn’t complaining dry mouth. This is accordance with the literature, dry mouth gel can improve signs and symptoms of dry mouth and increase the patient's ability to swallow. Patient’s take antihypertensive drugs have manifestations in form of xerostomia. The treatment carried out to improve the condition of  patient's oral cavity is providing education on maintaining healthy teeth and mouth as well as using dry mouth gel applied to the entire oral mucosa. In this case, an increase salivary rate from 0.16 mL/minute to 0.38 mL/minute. The concluded, use of dry mouth gel is effective in treating xerostomia and can increase the rate of saliva in the oral cavity
Treatment for an Altered Passive Eruption (APE)
Authors: Muslim Irwandi , Andriani Ika
Published: April 2024

Altered Passive Eruption (APE) is a condition where the gingival margin is more incisal or occlusal than the cementoenamel junction. Apart from disrupting the aesthetics of a smile, this condition can also be a risk factor for periodontal disease. APE is characterized by a gummy smile and short-looking teeth. Periodontal crown lengthening surgery is a treatment option that can be given to treat this case. The choice of periodontal crown lengthening surgery procedure must be adjusted based on the APE classification of the patient's case. This case report aims to describe the management of APE type 1A with periodontal crown lengthening surgery through gingivectomy. A 25-year-old female patient came to RSGM UMY with complaint that the gums on the front teeth of the upper jaw seemed large. The patient's general health is good. The results of intraoral examination showed that there were an elevation of the gingiva towards the incisal direction, and the teeth appeared short on 12, 11, 21, and 22. The examination also showed the presence of cretinized gingival tissue that appeared larger vertically on 12, 11, 21, and 22. On radiographic examination, the distance between the cementoenamel junction and the crestal bone is greater than 1 mm. The patient's APE classification was type 1A, hence gingivectomy was performed in this case. In treating APE cases, determining the correct diagnosis and selecting appropriate therapeutic management must be considered according to the patient's case. All therapeutic decisions must be discussed with the patient in order to satisfy their desires
Management of Herpangina in 2 Years-Old Patient
Authors: Femilian Afryla , Pramono Ananda Ayu
Published: April 2024

Herpangina is an acute viral infection caused by Enterovirus 71. This infection generally occurs in children under 10 years old and can heal within 4-7 days. Herpangina is characterized by the appearance of ulcers with discomfort pain  in the posterior area of ​​the oral cavity like  tonsils, uvula and soft palate. A 2-year-old came with his mother, complaining of a large number of sores in his mouth and anorexia. 2 days ago he had fever. To describe management and treatment of herpangina in a 2 years old patient. Herpangina is a self-limiting disease. Dentists can give symptomatic and supportive therapy to support the healing process. In addition, maintaining the cleanliness of the environment and the oral cavity can reduce the risk of recurrence or other viral infections.
Extraction Management of Gangrene Radix with Radicular Cyst
Authors: Firgina Widya , Setyawan Erwin
Published: April 2024

Introduction: Radicular cysts are the most common type of cyst found in the teeth and mouth are associated with pulp necrosis and tooth root canal infections. Treatment that can be done for radicular cysts consists of surgical and non-surgical treatments, treatments such as tooth extraction. This case report describes the results of managing tooth root extraction with a radicular cyst. Case Report: A 22-year-old woman complained that her lower right back tooth had root residue. Objective examination revealed that her two  roots remain, mesial and distal to tooth 46 Percussion (-) and palpation (+) revealed an asymptomatic, firm consistency, nodular lesion  1 cm in size. Radiographic examination showed a radiolucent area on tooth 46 with a clear and firm base in the shape of a semicircle measuring ± 1 cm. Case management: The tooth was extracted using a technique called infiltration anesthesia. Conclusion: Establishing a good and correct diagnosis in cases of radicular cysts can provide appropriate treatment for patients by knowing the characteristics of the lesion. Tooth extraction with optimal elimination of infected tissue is one of the treatments that can be carried out in radicular cysts
Bone Regeneration on Chronic Apical Abscess After Root Canal Treatment
Authors: Ragil Hayunda , Mutmainnah Ayu Annisa , Aristiyanto Regia
Published: April 2024

Chronic Apical Abscess is explained as an inflammatory reaction to pulp infection and necrosis. It is characterized by intermittent discharge of pus through an intraoral sinus tract and usually associated with little or no discomfort. On radiograph examination showed radiolucency as signs of periapical bone destruction. Root canal treatment can elimination bacteria as source of the infection in root canal system. Purpose: these two case report aims to present the management of chronic apical abscess with bone destruction in periapical area. Case report: (1) A 21-years-old female came to complained of a lack of self-confidence due to her upper-front tooth was broken about 8 years ago. Clinical examination showed  no discomfort on percussion test, negative on palpation and vitality test. Periapical radiography showed a radiolucent with clear but indistinct boundaries, oval in shape with a diameter of approximately 4 mm. (2) A 20-years-old male complained that his front teeth were broken and discoloured. This complaint had been felt for a long time about 7 years ago. The patient had felt spontaneous pain in the tooth that was hit during the accident for a week. Currently, the tooth is no longer painful. There is no swelling in the gum area where the tooth has changed colour. Radiological examination showed bone damage with a periapical radiolucent appearance with diffuse oval borders with a diameter of 5-6 mm. The diagnosis of these two cases were pulp necrosis with chronic apical abscess. Root canal treatment were performed to elimination bacteria of source infection. First case was restoration using composite resin crown with fiber post intracanal restoration and the second case was restoration using direct restoration. Conclusion: proper root canal treatment resulting bone regeneration  and periapical lesions healing  in chronic apical abscess cases.
Exploring the cessation efficacy and harm reduction potential of heated tobacco and nicotine pouch products in smokers and smokeless tobacco users: study protocol of a 6-month randomized controlled switching trial
Authors: Pluym Nikola , Burkhardt Therese , Scherer Max
Published: April 2024

Background: Despite decades of research on pharmacological and behavioural smoking cessation treatments, current quit aids are of limited success. The introduction of new, combustion-free nicotine and tobacco products extended the tool kit for people who smoke to switch away from their risky habit. We performed a systematic review including 120 studies resulting in several recommendations for a robust study design to determine the cessation efficacy of a new nicotine or tobacco product. Consequently, we prepared this study protocol to assess the cessation efficacy of heated tobacco products (HTPs) and nicotine pouches (NPs).
Methods: 250 subjects (125 exclusive smokers and 125 exclusive smokeless tobacco (SLT) users) will be recruited and offered a choice of HTPs in case of smokers and a choice of NPs in case of SLT users in order to switch. Subjects will undergo four visits (baseline, 1, 3, and 6 months) to collect biospecimens and for physical examinations. Use behaviour and questionnaires will be monitored on a regular basis by means of a smartphone-app. We describe a sensitive and specific compliance monitoring using suitable biomarkers of exposure. The sample size of 250 subjects and duration of 6 months will allow the quit rates to be assessed with sufficient statistical power. Finally, the choice between different products shall reflect the individuals’ preferences.
Conclusions: This protocol can be applied generically, providing a robust determination of a products’ cessation efficacy.
Trial Registration: The trial will be registered in the International Clinical Trials Registry Platform.
Diagnostic accuracy of pocket-size lung ultrasound for etiological definition of pneumonia and surveillance of complications in children hospitalized: a prospective diagnostic cohort study
Authors: Monteiro Sara , Tavares Teresa , Salazar Luís , Coelho Filipa , Carvalho João , Barbosa Telma , Reis Maria G. , Morais Lurdes , Ramos Ana , Ferreira-Magalhães Manuel
Published: April 2024

Background: Pneumonia, the leading infectious cause of death in children worldwide, often requires a chest radiograph (CXR) for diagnosis, involving radiation exposure. Point-of-Care Ultrasound (POCUS) offers a radiation-free alternative and, specifically the pocket-size variant, enhances convenience at the patient's bedside. While evidence supports ultrasound's accuracy in detecting community-acquired pneumonia (CAP) in children comparable to CXR, few studies have explored its ability to distinguish pneumonia etiology, especially utilizing pocket-size POCUS devices.
Methods: In this prospective diagnostic cohort study conducted over a year in a tertiary pediatric referral center, we aim to assess the diagnostic accuracy of a pocket-size POCUS device compared to CXR for determining the etiology of CAP in pediatric patients (aged >6 months and <18 years). At least 76 participants diagnosed with CAP will undergo independent POCUS examinations at various intervals, complemented by CXRs when necessary, independently classified by a third investigator. The General Electrics Vscan AirTM®, featuring Bluetooth connectivity to smartphone/tablet, will be employed for POCUS. Data collection will include systematized POCUS and CXR descriptions, alongside sociodemographic, clinical, and therapeutic variables. Statistical analysis using SPSS® version 28 will evaluate the diagnostic accuracy of the POCUS device.
Conclusions: This trial's outcomes hold significant promise in unveiling unknown data about the diagnostic accuracy of pocket-size POCUS for pediatric CAP etiological diagnosis. Utilizing a device meeting technical recommendations, featuring a dual-headed probe and Bluetooth connectivity, this study has the potential to bring innovation to clinical practice, improving patient care and creating scientific value.
Trial Registration Number: NCT06296693.
Comparison of the effects of two concentrations of adrenaline (0.33 mg/l versus 1 mg/l) in the irrigation serum for arthroscopic shoulder surgery: protocol of a randomized controlled trial
Authors: Harly Edouard , Billaud Anselme , Demezon Hugues , Joudet Thierry , Tournier Clément , Pincin Antony
Published: April 2024

Background: Controlling bleeding during arthroscopic shoulder surgery helps improve the clarity of the arthroscopic visual field. Adrenaline is considered an effective and safe method to reduce bleeding. Two doses of adrenaline (0.33 mg/l and 1 mg/l) have been evaluated in the literature, but never against each other.
Methods: This prospective, double-blind, randomized controlled trial will study the clarity of the visual field using a numerical scale (NS) during rotator cuff surgery on 180 patients across 5 centres. The secondary objectives include: the duration of the operation, volume of saline used, increase in baseline pressure, number of arthropump hyperpressures, mean systolic blood pressure and heart rate, as well as sudden variability.
Results: Among the 154 patients in the Clinical Trial Group, 70/154 (45%) continued to have proteinuria, while 84/154 (55%) had no proteinuria (remission) compared to 41 (28%) in remission and 104 (72%) with continued proteinuria in the Usual Care group (p<0.001).
Conclusions: This study aims to determine which of the two dosages previously studied in the literature (0.33 mg/l versus 1 mg/l) provides better clarity.
Trial Registration Number: 2021-A02773-38.
Genetic diversity and stability analysis based on agro-morphological traits among rice genotypes developed through marker-assisted backcrossing
Authors: Oginyi Jeremiah C. , Chukwu Samuel C. , Paul Kelechi U. , Mkpuma Kenneth C.
Published: April 2024

Background: The genetic diversity and stability analysis based on agro-morphological traits among rice genotypes developed through SSR marker-assisted backcrossing was evaluated at college of agricultural science (CAS), Ebonyi State niversity, Abakaliki, Nigeria.  
Methods: In this study, 9 rice accessions sourced from the Iinstitute of tropical agriculture and food security (ITAFoS), universiti Putra, Malaysia and Ebonyi, Nigeria; were evaluated for yield stability performance. The experiments were laid out in randomized complete block design (RCBD) with three replications each for two seasons.
Results: Result of the evaluated rice accessions showed highly marked morphological variability based on the mean performance and were grouped into three main clusters. Cluster I had CP, cluster II contained Line4, Line5, Line6, and Line8, and cluster III had Line1, Line7, Line12, and Putra-1. The first, 3 principal components were identified and retained for having the Eigen-value >1. The first PC had an eigenvalue of (6.30) with 52.5% proportion of which plant height accounted most for this variation with (0.359) whereas panicle length contributed the least (-0.13). For stability analysis, CP had highest values for most of the parameters. High heritability value was recorded for all nine traits which range between 71.04% and 95.06%. The highest heritability value (95.06%) was found in Days 50% heading while grain width had the lowest (71.04%).
Conclusions: It could be concluded that CP, Putral-1, and line7 were the most stable in terms of yield across the two seasons of this study; hence, recommended for parental materials for hybridization.
Screening of diabetes mellitus in patients at risk in dermatology outpatient department
Authors: Kaul Kanishka
Published: April 2024

Background: Type 2 diabetes mellitus (T2DM) is a widely spread multidisciplinary condition that requires the attention of many different disciplines; yet, the involvement of dermatologists in this regard has not been recognized. The current study focused on the role of dermatologists in screening the prevalence and pattern of cutaneous manifestations in diabetic and pre-diabetic patients.
Methods: A randomized study was carried out from April 2023 to October 2023 in the department of dermatology at SSB Heart and Multispecialty Hospital in Faridabad, Haryana. In the current study, patients with dermatological problems suspected of diabetes mellitus were enrolled. Dermatological problems such acanthosis nigricans, dermatophyte infections, psoriasis, endogenous eczema, chronic urticaria, generalized pruritus, lichen simplex chronicus, patients older than 40, and coexisting conditions like obesity were focused in this study.
Results: This study enrolled a total of 100 patients. Only 37 patients were recognized as having a high risk of diabetes, with 67.57% having a verified history of the disease. Furthermore, 32% of T2DM patients were examined for specific skin symptoms during their initial visits, with 4 individuals being found to have generalized pruritus and dermatophyte infection.
Conclusions: This study finally concluded that dermatologists may play a crucial role in fighting the T2DM epidemic by early detection of T2DM and treatment initiation which may reduce the risk of serious complications.
N-terminal pro-brain natriuretic peptide current trends in diagnostics
Authors: Sukumaran Ajaikumar , Raveendran Haritha P , Krishnan Arun R , Paul Jofy K , Vasudevan D M
Published: April 2024

N-terminal pro-brain natriuretic peptide is the prime standard biomarker used for heart diagnosis and prognosis. Owing to the acute response and considerable half-life, the N-terminal pro-brain natriuretic peptide is the most reliable biomarker to identify a cardiac injury. N-terminal pro-brain natriuretic peptide can act as an independent risk factor for the COVID-19 infected patients, but the exact reason for raise in the level of biomarker is still unclear. Various immunological platforms like immunofluorescence, enzyme linked immunosorbent assay, lateral flow immunoassay, chemiluminescence immunoassay, stable isotope standards capture by anti-peptide antibodies assay are used to detect the N-terminal pro-brain natriuretic peptide from human blood. Chemiluminescence immunoassay lead the diagnostic platform for the determination of N-terminal pro-brain natriuretic peptide due to high stability, ultra-sensitivity, specificity, and high throughput.
Efficacy and safety of ebastine 10 mg and phenylephrine 10 mg fixed-dose combination in Indian patients with allergic rhinitis: A phase 4 multicentre study
Authors: S Manjula , Srinivas CV , Chavan Shrinivas , S Ramesh , Adgaonkar Nitin Chandrashekhar , M Krishna Kumar
Published: April 2024

There is a lack of comprehensive studies examining the efficacy and safety of the fixed-dose combination (FDC) of ebastine 10 mg and phenylephrine 10 mg in allergic rhinitis (AR), especially in Indian settings. So, this study aimed to fill the existing research gap by evaluating the efficacy and safety of the FDC ebastine 10 mg and phenylephrine 10 mg in Indian patients with moderate/severe persistent AR.

An open-label, non-randomized, single-group, multicentric, phase 4 clinical study included adult patients visiting the outpatient departments of 4 sites across India. All the selected subjects received the FDC once daily in the evening for 5 days. Safety and efficacy of the FDC were evaluated by comparing the Individual Symptoms Score (ISS), Total symptom Score (TSS), and analysing adverse event profiles reported by patients, assessed by the investigator, from baseline to 6 days. The study also assessed the impact of this condition on patients' quality of life using the rhino-conjunctivitis quality of life scale (RQLS).

The study included 145 participants with a mean age of 37.17 ± 12.65 years and male-to-female ratio of 1:1.26. Comparison of baseline symptoms with day 6 revealed statistically significant and clinically meaningful improvements in Individual Symptoms Score (ISS). The mean difference in Total Symptom Score (TSS) from baseline to day 6 also showed a substantial improvement of 3.52 ± 1.54 (95% CI: 3.27-3.78; P <0.001). Rhino-conjunctivitis quality of life scale (RQLS) also demonstrated statistically significant improvement from day 1 to day 6 (t = 24.44, P <0.001). Adverse events were effectively managed with the use of readily available over-the-counter medications like antipyretics, analgesics, and/or antacid.

The study validated the efficacy and safety of the FDC ebastine 10 mg and phenylephrine 10 mg, in managing AR with good safety profile. The findings underscore the importance of this combination as a viable therapeutic option, with significant improvements in symptom scores and quality of life observed within a short duration.
A prospective study on clinical profile, severity, microbiology, and outcome of patients with ventilator associated infective complications admitted in intensive care unit of a tertiary care hospital
Authors: Sen Subhajit , Ramasubban Suresh
Published: April 2024

: Mechanical ventilation epitomizes intensive care medicine. Ventilator‑associated complications are mainly Ventilator associated respiratory infections (VARI); These are a major cause of concern in the intensive care units (ICUs) worldwide, especially in developing countries. VARI includes patients with ventilator‑associated tracheobronchitis (VAT) and ventilator‑associated pneumonia (VAP).

The clinical profile, severity, microbiology, and outcomes of such infections is not well described in Eastern India.

The primary objective of the study was to study the risk factors, severity scoring, microbiological profile and 28 days outcome of patients admitted in intensive care unit of our hospital.

Secondary objective of our study was to find out any correlation between risk factors, severity scoring, microbiological profile, and outcome of patients with VAT and VAP admitted in intensive care unit of our hospital.

: This was a prospective observational study done in the ICU of a tertiary care centre in eastern India. A total 50 patients of clinically, microbiologically and/or radiologically diagnosed case of VAP and VAT were included in the study. A structured data collection proforma was prepared and data collection was done. Raw data was tabulated and analysed

: 66% of our patients were male, Smoking was the commonest addiction(24%), VARI developed early with 17% on Day 3, 72% developed VARI within 5 days of ventilation. 16% had history of recent admission, Diabetes and hypertension were the commonest comorbidities. 58% of the patients developed VAP, the median SOFA score in VAP was 6 also similar in VAT. Patients with neurological diseases had the maximum number of VAT and VAP. Klebsiella pneumoniae was the commonest organism causing VAT (42%) while Acinetobacter Baumanii was commonest to cause VAP (44%). 51% of VAP patients were on volume control mode, while it was 52% of VAT patients. Most isolates are MDR pathogens with intermediate sensitivity to Polymyxin being most common (66%) 1 isolate was pan resistant. Mortality was 58% for VAP and 19% in VAT. Both Klebsiella and Acinetobacter accounts for 41% death in VAP group, in VAT group Klebsiella was commonest however no statistical significance with other organism.

: Gram negative bacteria were the predominant cause of VAT and VAP, Acinetobacter and Klebsiella are the commonest organisms. Most Isolates are MDR with intermediate sensitivity to Polymyxins. Median SOFA scores were the same in both. Mortality was high in VAP group. Volume control mode was predominant mode of ventilation, Neurological causes was predominant cause that leads to ventilation and subsequent VARI.
DESAFIOS DA TRADUÇÃO LITERÁRIA: ESTUDO COMPARATIVO DE DUAS TRADUÇÕES PARA O INGLÊS DE CONTO DE CLARICE LISPECTOR
Authors: Cabral Gladir da Silva , Regina Maciel Julia
Published: April 2024

O presente artigo tem como objetivo comparar duas traduções para a língua inglesa do conto “Os obedientes”, de Clarice Lispector, verificando as possíveis influências das escolhas dos tradutores na interpretação do texto. Com base em autores como Bassnett (2005), Bastín (1998), Steiner (2005) e Paz (2009), as traduções foram contrastadas de acordo com seis tópicos que foram considerados significativos para a análise de dados, sendo eles: a sintaxe, o léxico, a paragrafação, as metáforas, humor e ironia, e as adições. Como resultado, verificou-se que cada tradutor possui uma visão diferente em relação à fidelidade ao texto, o que gerou duas traduções distintas entre si; uma delas buscando maior aproximação ao texto original, enquanto a outra é mais flexível. A interpretação que cada tradutor faz do texto influencia nas escolhas e afeta o resultado final do texto. Assim, percebeu-se que não há apenas uma maneira de traduzir, principalmente em se tratando da tradução literária e, em particular, de um texto complexo como o de Clarice Lispector.
EDUCAÇÃO ESPECIAL E EDUCAÇÃO INCLUSIVA NA PERSPECTIVA DE CARLOS SKLIAR
Authors: Silveira Zelia medeiros
Published: April 2024

Esse texto, apresenta algumas das discussões realizadas na disciplina Seminário Avançado do Programa de Pós-Graduação em Educação (PPGE) da UNESC. A disciplina explorou aspectos teórico-metodológicos e epistemológicos presentes nas pesquisas dos doutorandos do Programa. O formato da disciplina consistiu em seminários apresentados pelos doutorandos, com a participação dos professores do programa, de acordo com a linha de pesquisa abordada. Esses encontros permitiram aprofundar os conceitos centrais dos textos e promover a integração entre os conteúdos que perpassam as diferentes linhas de pesquisa do programa, ampliando o debate sobre as investigações no campo da educação. Um dos autores estudados durante os seminários foi Carlos Bernardo Skliar, um pesquisador argentino que se dedica à área da educação especial, com foco na educação de surdos. Diante disso, este texto busca refletir sobre as concepções de educação especial e educação inclusiva presentes nas escolas, problematizando-as a partir das obras de Skliar, especialmente nos livros "Educação e Exclusão: abordagens socioantropológicas em Educação Especial" (1997), "A surdez: um olhar sobre as diferenças" (1998) e "Pedagogia (improvável) da diferença" (2003), bem como em alguns de seus artigos. Essa reflexão abordou os conceitos e ideias de Skliar relacionados à educação especial e inclusiva, explorando suas perspectivas críticas e socioantropológicas sobre o tema. A discussão ampliou a compreensão dos estudantes sobre as questões abordadas nas pesquisas realizadas pelo autor argentino e contribuiu para o debate e o aprofundamento do conhecimento no campo da educação. Nesse sentido, pensar a educação especial remete também a discussão da escola comum, e, por esse viés, tornando-se urgente questionar as bases teóricas em que está sustentado o currículo escolar e se o modelo da escola atual favorece a inclusão.
An Important Step on the Road to a High-Impact Journal
Authors: Sungur Mehmet Ali
Published: April 2024

An Important Step on the Road to a High-Impact Journal
Bioaccumulation of Pb (Lead) in the Muscles of Danio rerio and its Effect on the Anti-oxidant Enzyme Catalase in the Mining Vicinity of Kolar Gold Fields
Authors: Ashok D. , Harini B.P. , . Saraswati , Jagadisha T.V. , Kumar S. Arun , Calistus A.L. Jude
Published: April 2024

Background: The study has a bifold objectives, firstly to determine the concentration of lead (Pb) in the pond water and bioaccumulation of the lead in the muscles of Danio rerio raised with the same pond water. Secondly, the study seeks to investigate its effect on the anti-oxidant enzyme catalase in Danio rerio, within the vicinity of a historical gold mine region located in the Kolar Gold fields (KGF), Karnataka, India. Methods: To achieve the objectives, the study employed Thermo Scientific’s Inductively Coupled Plasma-Optical Emission Spectroscopy (ICP-OES) and ICP-AES using Iteva software to evaluate and statistically analyze the distribution of lead in the pond water and and ICP-OES to evaluate the concentration of lead in the muscles sample. Four sample sites (A, B, C and D) were selected based on their proximity to residential area. Pond water samples were analyzed between April and October 2022 following a southwest monsoon rain. Result: During the study in the pond water, sample site B and D exhibited an exceedingly high Pb concentration during October with 0.98 mg/L against 0.21 and 0.16 mg/L in April 2022 against the maximum permissible value of 0.05 mg/L by WHO 2008 and USEPA 2009, followed by site A and C. The control sample had a normal range of 0.01 mg/L. The concentration of Pb in the muscles on day 30 of October was exceedingly high in the sample site D with 1.9 mg/Kg against 1 mg/Kg on day 30 of April followed by the sample sites B,C and A, which is far above the threshold value as per the regulatory bodies (WHO 2008). The increase in the concentration of the lead decreases the catalase enzyme in the brain region of Danio rerio, the value goes down drastically from 112.3 (µM H2O2 utilized/min/mg protein) to 105.8 in sample site D between day 30 of April and October months, to that of the control value being stable from 151.7 to 150.94 (µM H2O2 utilized/min/mg protein). The outcome of this experiment will facilitate the assessment of pond water contamination levels and the likelihood of contaminants entering the aquatic environment, resulting in the bioaccumulation of heavy metals in the aquatic organisms. The above results clearly indicates the effect of south-west monsoon rain in increasing the levels of lead concentration in the pond water during the month of October to that of April, which indirectly affects the physiology and metabolism of the fishes raised in the contaminated habitat of Kolar Gold Fields.
Unveiling the Quality Traits and Longevity of Biscuits Formulated with Black Rice Flour [Oryza sativa (L.) indica]
Authors: Sangma Hymie Cherik R. , Parameshwari S.
Published: April 2024

Background: The study was aimed at producing biscuits made from black rice flour and analysing their proximate composition, mineral, antioxidant, glycaemic, organoleptic evaluation and shelf-life characteristics. Methods: Established methods were used to evaluate the proximate composition, mineral composition, antioxidant, glycaemic, sensory evaluation and shelf-life characteristics of the biscuits. Result: According to the results, the BRFB3 had a significantly higher content of dietary fibre and protein while it had a much lower content of carbohydrates, moisture and fat. Mineral content (p less than 0.05) was significantly different between the variants. BRFB2 scored higher in the sensory evaluation. All three biscuit formulations were found to have low GI values, the strongest antioxidant activity compared to the control sample. The biscuit formulations had a significant impact on the control and could be stored for a maximum of 30 days.
Does early neutering increase the risk of cranial cruciate ligament rupture?
Authors: Low Daniel
Published: April 2024

PICO Question
In bitches, does gonadectomy before 1 year of age compared to gonadectomy at 1 year of age or older, increase the risk of cranial cruciate ligament disease during their life?
 
Clinical bottom line
Category of research
Risk.
Number and type of study designs reviewed
Eight studies were reviewed, four of which were retrospective cohort studies, two of which were prospective longitudinal cohort studies, one of which was a retrospective case-control study and one of which was a prospective case-control study.
Strength of evidence
Moderate.
Outcomes reported
The evidence was mixed, but overall was suggestive that gonadectomy before 1 year of age increased the risk of cranial cruciate ligament disease in bitches. Gonadectomy before 1 year of age was found to increase the risk of cranial cruciate ligament disease in seven of eight studies. Most studies assessed a narrow range of breeds and the generalisability of these results to all dogs is thus limited. The one study which assessed a range of 35 breeds noted an increase in risk of cranial cruciate ligament disease in 6 of 35 breeds associated with gonadectomy before 1 year of age. Direct comparison of studies is limited by the varying age stratifications, breed analyses, and study methodologies.
Conclusion
Gonadectomy before 1 year of age in Golden Retriever, German Shepherd, and Rottweiler bitches may increase the risk of cranial cruciate ligament disease. In other breeds, limited evidence is available to draw conclusions.
 
How to apply this evidence in practice
The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.
Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.
The Effect Of Work-Life Balance, Job Burnout, Organizational Commitment on Turnover Intention at XYZ Hospital in Bekasi
Authors: Manurung Rahel Novianti , Bernarto Innocentius
Published: April 2024

Providing the best service in hospital is very important due to very competitive competition. Nurses are the main providers of services especially in private hospitals. The aim of this study is to assess the association between work-life balance, job burnout, and organizational commitment on turnover intention at XYZ Hospital in Bekasi. Data collection using online questionnaires from 120 nurses was done for this quantitative investigation. Work-life balance, job burnout, and organizational commitment were the independent factors, while turnover intention which was projected at the conclusion of the modelling process was the dependent variable. Partial least squares-structural equation modelling (PLS-SEM) was utilized in data analysis. The findings showed that work-life balance has a negative effect on job burnout, work-life balance has a positive effect on organizational commitment, job burnout has a positive effect on turnover intention, organizational commitment has a negative effect on job burnout, and work-life balance has a negative effect on turnover intention. Based on the results of this study, it can be concluded that job burnout has a very strong influence on turnover intention
Financial Loss and Financial Well-Being of Emerging Adults During COVID-19: The Limitations of Psychological Resilience
Authors: Ranta Mette , Li Lijun , Vosylis Rimantas , Sorgente Angela , Crespo Carla , Fonseca Gabriela , Lanz Margherita , Lep Žan , Lonka Kirsti , Relvas Ana Paula , Salmela-Aro Katariina , Zupančič Maja , Serido Joyce
Published: April 2024

Amid the COVID-19 pandemic, emerging adults are especially vulnerable as they experience its financial impact as a source of stress. We tested a model of psychological resilience among emerging adults (18–25 years) during the pandemic from six Western countries (Finland, Italy, Lithuania, Portugal, Slovenia, and United States) using online survey data collected between May and September 2020. Framed in the conservation of resources theory, we examined the association between financial loss and financial well-being and the moderating role of psychological resilience in the association. Using path analysis, we found a direct negative association between financial loss and financial well-being, a direct positive association between psychological resilience and financial well-being, but no evidence of moderation. We discuss the findings in the context of continuing global economic uncertainty and the support needed to foster adult independence and financial well-being of emerging adults.
The Contribution and Philosophical Development of the Reformational Philosopher Herman Dooyeweerd: An Historical Overview
Authors: Ive Jeremy
Published: April 2024

Herman Dooyeweerd and Dirk H. Th. Vollenhoven played complementary roles in the development of Reformational philosophy. This paper examines the role that Dooyeweerd had to play and examines the development of his philosophy.
Hibridación y organización retórica en los Cantares de Dzitbalché
Authors: Craveri Michela
Published: April 2024

El presente trabajo se propone el estudio del lenguaje poético de los Cantares de Dzitbalché. A pesar de su importancia en el ámbito literario, los textos contenidos en este manuscrito maya han recibido escaso interés desde el punto de vista retórico. Sin embargo, el uso de los paralelismos y de otras figuras de profundización semántica hacen de esta obra un ejemplo magistral de poesía maya. Asimismo, se puede observar en los textos una influencia de la tradición hispánica a nivel morfosintáctico y temático, que también será analizada y discutida a lo largo del trabajo.
Dynamic parameters of a car with a SI engine fueled with LPG/DME blends
Authors: Marzec Paweł , Kubica Grzegorz
Published: April 2024

The paper presents an analysis of the dynamic parameters of a compact class passenger car powered by LPG/DME blends. The presented results are part of the research cycle of this vehicle, the purpose of which was to check the possibility of using DME (dimethyl ether) as an additive in the fuel mixture with LPG. In the presented part of the experimental research, the acceleration times of the vehicle under specific conditions were measured. On the basis of the obtained results, the relations between the average acceleration in the tested speed ranges, the fuel composition and the degree of engine load were developed. The results of the analyzes indicate that in the examined range of changes in the DME share in the fuel, comparable or higher acceleration values were obtained for all engine load levels. This confirms the usefulness of DME as a fuel component used to power SI engines.
Artificial intelligence as a part of public life: ethical and legal problems and their solutions
Authors: Babenkova Victoria R. , Kravchenko Natalia V.
Published: April 2024

The ethical and legal problems of artificial intelligence’s comprehensive integration into the public environment, its impact on the human life sphere are investigated. The intensity of the ongoing changes requires not only full-fledged legal regulation, but also a comprehensive study of both the positive aspects of innovations, as well as the foresight of possible threats and the formation of adequate protective mechanisms from the law point of view, from the standpoint of human moral values. It is a systematic approach and the possible negative consequences’ prevention of the artificial intelligence use that should shape the goal-setting of the development and implementation of such systems. Using scientific cognition methods, such as analysis, synthesis, system-analytical, formal-logical, system-legal, various approaches to understanding the definition of “artificial intelligence” have been studied, taking into account all the features of such systems, the necessary ways to solve the identified gaps in legal regulation related to determining the place of objects and artificial intelligence systems in the legal space. The social and practical significance of the development of robotics is touched upon, while attention is focused on the regulation of possible risks. It is concluded that it is the compliance of the functions performed by artificial intelligence with the ethical and moral canons of society that should be decisive in solving issues of responsibility. Separately, proposals are presented to determine civil liability both in cases of direct harm by robots with artificial intelligence, and in cases of damage or destruction of an artificial intelligence system by a third party to their owner.
Effects of post-exercise intake of exogenous lactate on energy substrate utilization at rest
Authors: Kim Taeho , Hwang Deunsol , Kyun Sunghwan , Jang Inkwon , Kim Sung-Woo , Park Hun-Young , Lim Kiwon , Kim Charyong , Kim Jisu
Published: April 2024

[Purpose] This study investigated the effects of exogenous lactate intake on energy metabolism during 1 h of rest after acute exercise.[Methods] Eight-week-old ICR mice were randomly divided into four groups: SED (no treatment), EXE (exercise only), LAC (post-exercise oral lactate administration), and SAL (post-exercise saline administration) (n=8 per group). The exercise intensity was at VO2max 80% at 25 m/min and 15° slope for 50 min. After acute exercise, the LAC and SAL groups ingested lactate and saline orally, respectively, and were allowed to rest in a chamber. Energy metabolism was measured for 1 h during the resting period.[Results] LAC and SAL group mice ingested lactate and saline, respectively, after exercise and the blood lactate concentration was measured 1 h later through tail blood sampling. Blood lactate concentration was not significantly different between the two groups. Energy metabolism measurements under stable conditions revealed that the respiratory exchange ratio in the LAC group was significantly lower than that in the SAL group. Additionally, carbohydrate oxidation in the LAC group was significantly lower than that in the SAL group at 10–25 min. No significant difference was observed in the fat oxidation level between the two groups.[Conclusion] We found that post-exercise lactate intake modified the respiratory exchange ratio after 1 h of rest. In addition, acute lactate ingestion inhibits carbohydrate oxidation during the post-exercise recovery period.
Contribution of Self-efficacy and Optimism on Nurse Work Engagement
Authors: Dewanti Nisa , Prakosa Mira Melynda
Published: April 2024

Introduction: Work engagement for nurses is needed to increase dedication so that health organizations run effectively and efficiently. Self-efficacy and optimism are components of personal resources that can predict work engagement. This research aims to see the contribution of the role of self-efficacy and optimism to nurses' work engagement.
Methods: This was a cross-sectional study. A cluster sampling technique was used to recruit 130 nurses.  Data on self-efficacy, optimism, and nurse work engagement were collected by questionnaire, and analyzed by logistic regression techniques.
Results: Self-efficacy and optimism in nurses had a significant effect on nurse work engagement with the sig values 0.011 and 0.000. These make nurses more persistent, enthusiastic, and focused at work.
Conclusions: Nurses who have high self-efficacy are always confident in their abilities. Likewise, nurses who have high optimism tend to be more confident and have high persistence at work, so that work engagement will be formed well. Future studies should place greater emphasis on exploring new nurse’s self-efficacy and optimism.