bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS PENERAPAN MODEL PURCHASING POWER PARITY UNTUK MEMPREDIKSI NILAI TUKAR RUPIAH TERHADAP US DOLLAR (Periode Januari 2016 – Desember 2018)
Authors: Tamonsang Matheous , Arochman Maqbulla
Published: September 2022

ABSTRACT

 

This study aims to test the ability of the purchasing power parity model used to predict the exchange rate of the rupiah against the US dollar based on differences in inflation in the two countries. Determination of the sample in this study using purposive sampling method by time series per month during the period January 2016 - December 2018 as many as 36 months. The results of this study are that first, the difference in inflation rates in Indonesia and the United States has a significant effect on changes in the US Dollar exchange rate. Second, the purchasing power parity model is still feasible to be used to predict the rupiah exchange rate against the US dollar. These results are shown by the significant effect of differences in inflation in the two countries on changes in exchange rates, supported by the regression results of purchasing power parity that meet the requirements of the assumption test.

 

Keywords: Purchasing Power Parity, Rupiah, Dollar, Inflation
ANALISIS STRUKTUR MODAL PERUSAHAAN MAKANAN DAN MINUMAN MELALUI PERTUMBUHAN PENJUALAN DAN TARIF PAJAK
Authors: Linda Marlindawaty
Published: September 2022

ABSTRAK

Struktur modal merupakan suatu hal yang sangat penting bagi suatu perusahaan terutama untuk keuangan dan nilai perusahaan sehingga manajer keuangan harus memahami faktor-faktor yang mempengaruhi struktur modal agar dapat memaksimalkan kemakmuran para pemegang saham perusahaan. Tujuan dari penelitian ini adalah untuk mengetahui bagaimana pengaruh pertumbuhan penjualan dan tarif pajak terhadap struktur modal pada perusahaan makanan dan minuman yang terdaftar di Bursa Efek Indonesia (BEI) periode 2013-2017. Penelitian ini menggunakan leverage sebagai proksi dari struktur modal. Analisis regresi yang digunakan adalah analisis regresi linier berganda. Berdasarkan pembahasan hasil penelitian, pertumbuhan penjualan berpengaruh signifikan terhadap struktur modal dan tarif pajak tidak berpengaruh terhadap struktur modal pada perusahaan makanan dan minuman.

Kata Kunci : Struktur Modal, Pertumbuhan Penjualan, Tarif Pajak

ABSTRACT

Capital structure is a very important for a company, especially for finance and company value, so that financial managers must understand the factors that influence the capital structure in order to maximize the prosperity of the company’s shareholders. The purpose of this research was to find out how the effect of sales growth and tax rate on the capital structure of food and beverages companies listed on the Indonesia Stock Exchange for the period 2013-2017. This research uses leverage as a proxy of the capital structure. The regression analysis used is multiple linear regression analysis. Based on the discussion of the results of the research, the sales growth has a significant effect on the capital structure and the tax rate has no effect on the capital structure of the food and beverages companies.

Keywords : Capital Structure, Sales Growth, Tax Rate
PENGELOLAAN ASSETS PERUSAHAAN DALAM OPTIMALISASI LABA
Authors: Juwari Juwari , Sudjinan Sudjinan , Anita Salim Ting
Published: September 2022

The purpose of this research is to find out the extent of the company's financial performance in order to manage the company's assets in achieving optimal profit, the performance of the management of the company's assets can be seen from the Activity Ratio, namely Cash Turnover, Receivables Turnover, and Inventory Turnover, based on the results of analysis both simultaneously and partially to the optimization of profit. The object in this study is PT. Indofood Sukses Makmur, Tbk, while the data used is the financial statements of PT. Indofood Sukses Makmur, Tbk, the first quarter of 2010 – the fourth quarter of 2020. The data analysis method uses multiple linear regressions with classic assumption test, F Test (simultaneous), and t test (partial). Based on the classic Assumption test does not occur multicolerity, autocorrelation and heteresdastisitas. The results of simultaneous analysis (Test F) show that Cash Turnover, Receivable Turnover, and Inventory Turnover have a significant influence.
EVALUASI KINERJA TENAGA PENDIDIK MELALUI CLASSROOM ACTION RESEARCH
Authors: Ariani Hj. Misna Ariani
Published: September 2022

Artikel ini, merupakan penelitian/evaluasi terhadap kinerja tenaga pendidik (dosen) ditinjau dari action research. Evaluasi dosen dilakukan terhadap kegiatan belajar mengajar mahasiswa A1 Program Studi Manajemen Fakultas Ekonomi Universitas Balikpapan, selama 1 semester (6 bulan). Tujuan dari penelitian/evaluasi ini adalah untuk mengetahui kinerja dosen melalui: 1. Kegiatan belajar mengajar, 2. Kehadiran dosen. 3. Kemampuan mahasiswa dalam mengimplementasikan dalam bentuk presentasi di kelas. Data untuk mengevaluasi  merupakan aktivitas belajar mengajar selama 16 kali pertemuan selama 1 semester. Data berupa kegiatan mahasiswa dalam perkuliahan dan kehadiran dosen di dalam kelas. Perkuliahan saat pandemic covid-19 berbeda dengan saat sebelum ada pandemic. Sebelum pandemic perkuliahan dilakukan dikelas dengan cara tatap muka dan aksi kelas, sedangkan pada saat  pandemic perkuliahan tetap dengan cara tatap muka tetapi tidak di dalam kelas langsung, namun menggunakan aplikasi Zoom. Hasil penelitian menunjukkan bahwa kehadiran mahasiswa tetap tinggi (rata-rata, 15 kali tatap muka) jumlah kehadirannya, Kehadiran dosen tetap seperti saat tatap muka di kelas secara langsung, Mahasiswa mampu menyerap materi kuliah, dengan bukti mampu mempresentasikan matakuliah yang ditempuh, yaitu Seminar MSDM.
THE EFFECT OF MOTIVATION, DISCIPLINE, AND THE WORKING ENVIRONMENT ON EMPLOYEE’S JOB SATISFACTION
Authors: Dedy Deomedes Stepanus , Adam Muhammad
Published: September 2022

This study aims to determine the effect of work motivation, discipline and work environment on job satisfaction of the employees of Balikpapan Local water Supply Company (PDAM). This research was conducted on the employees of the Balikpapan PDAM. The sample sizes taken were 187 employees. The results show that there is simultaneous effect of work motivation, discipline, and work environment to job satisfaction. Work motivation partially has a positive and significant effect on job satisfaction. Discipline partially has a positive and significant effect on job satisfaction and the work environment partially has a positive and significant effect on job satisfaction. The most dominant influence on job satisfaction is discipline.
PENGARUH PENDAPATAN ASLI DAERAH, DANA PERIMBANGAN, LAIN-LAIN PENDAPATAN DAERAH YANG SAH TERHADAP BELANJA DAERAH KOTA BALIKPAPAN
Authors: Susilowati Dwi , April Dayanti Sitinjak Christine , Juwari Juwari
Published: September 2022

ABSTRACT

This research aims to know the influece of simultaneus or partially variable Local Revenues, Balance Funds, Other Legitimate Income Toward Regional Expense on Balikpapan city. In year 2010-2018 obtained from the Office Regional Financial and Asset Management of Balikpapan. The technique of determination of sample in this study using saturated sample. Test result simultaneously that The effect of Local Revenues, Balance Funds, and Other Legitimate Income Toward Regional Expense on Balikpapan city. Collectively have a not significant influence on the Balikpapan city. Because Fhitung is smaller that Ftabel. While the test resulhts that partially Local Revenues has a positive effect and significant, Balance Funds has a positive effect and not significant, and Other Legitimate Income has a negative effect and not significant. Test resulhts that partially Local Revenues has a dominant influence Regional Expense on Balikpapan city because value thitung and the partial r most large compared to other variable second.
PENGARUH GAYA KEPEMIMPINAN DAN BUDAYA ORGANISASI TERHADAP KINERJA KARYAWAN MELALUI KOMITMEN ORGANISASI PADA DINAS PENDIDIKAN PEMUDA DAN OLAHRAGA KABUPATEN SIKKA
Authors: Arifin Taufik , Moa rodja Murjali
Published: September 2022

The purpose of this study was to examine the influence of situational leadership styles

on employee performance through a commitment to the Sikka District Youth and Sports Education Office. The number of samples in this study was 60 employees taken using saturated sampling or census sampling. Data were collected through a questionnaire distributed to 60 employees of the Office of Youth and Sports Education in Sikka Regency; 60 questionnaires were collected again which were taken by the census. In this study, the validity test was performed by Pearson's product-moment correlation technique. The analysis technique used in data processing is multiple regression analysis and hypothesis testing using the classic assumption test, f test, and t-test as the basis for decision making. The results showed that there was no significant effect between leadership style and employee performance, with a t value of only -0.812 through the t-test. But there is a direct effect of the intervening variable of organizational commitment on employee performance where the t value of 2.222 is greater than the value of t table 2.004. The leadership style does not have a direct influence on employee performance and it turns out that through the f test it was found that it is more effective with the indirect effect mediated by intervening variables of organizational commitment. While the direct and indirect relationship of organizational culture has significant results on employee performance, it means that organizational culture has a significant influence on improving employee performance at the Department of Youth and Sports Education in Sikka Regency
KINERJA KARYAWAN DI MASA PANDEMI COVID-19
Authors: Ariani Misna , Arrywibowo SU Imam , Rafiqa Rahim Ria
Published: September 2022

The Covid-19 pandemic has affected organizations in carrying out company activities to remain productive. Government regulations regulate companies to work from home. Therefore, employee performance is important for the survival of the company. This study aimed to determine whether employee performance is influenced by motivation, job satisfaction, and work environment. The population of this study was 53 permanent employees of PT. Mulia Jaya Mandiri Balikpapan, with a saturated sampling technique, the entire population is sampled. Data analysis includes validity test, reliability test, multiple linear regression test, t-test, and F-test. The results show that performance is influenced by motivation, job satisfaction, and work environment. Job Satisfaction partially has a negative and significant effect. And the dominant motivation affects the performance of employees of PT. Mulia Jaya Mandiri Balikpapan.
ANALISIS ELASTISITAS PERMINTAAN PRODUK TEMPE DI KELURAHAN SENDANG MULYASARI KECAMATAN TONGAUNA KABUPATEN KONAWE
Authors: Heriswanto Heriswanto , Alam Kendek Membaka Radiasi
Published: September 2022

Sendang Mulya Sari merupakanKelurahan penghasil Tempe yang terbesar di Kabupaten konawe, dengan adanya industri tempe rumahan banyak masyarakat yang membuka usaha beraneka ragam menurut usia, pendapatan, dan tingkat pendidikannya.menjual tempe dengan cara berlangganan di Industri tersebut. Dengan masa covid19 hari ini industri ini menjadi salah satu peluang masyarakat kabupaten konawe untuk melangsungkan kehidupannya baik berlangganan langsung ataupun dengan sistem on line. Penelitian ini bertujuan untuk menganalisis Elastisitas Permintaan Produk Tempe di Kelurahan Sendang Mulyasari Kecamatan Tongauna Kabupaten Konawe. Alat analisis yang digunakan dalam penelitian ini adalah metode dekriptif  kualitatif yaitu menganalisis data dengan secara induktif.Berdasarkan hasil penelitian, didapatkan bahwa menurut informan bahwa elastisitas permintaan produk tempe di kelurahan sendang mulyasari dikatakan inelastis hal ini karena Ed < 1. Elastisitas PermintaanTempe di Kelurahan Sendang Mulyasari tergolong inelastis yaitu nilai d (permintaan) lebih besar dari 1 (Ed = <1 ). Pada jenis elastisitas ini konsumen kurang peka terhadap  perubahan harga. Artinya, meskipun harga naik atau turun, masyarakat akan tetap membelinya. Saran bagi produsen produk tempe hendaknya mempertimbangkan faktor-faktor yang mempengaruhi elastisitas permintaan tempe seperti faktor jenis produk,faktor harga, faktor selera, faktor pendapatan konsumen, faktor ketersediaan produk, dan kualitas produk. 

Sendang Mulya Sari is the largest tempe-producing village in Konawe Regency, with a home-based tempe industry, many people open businesses that vary according to age, income, and education level. Selling tempeh by subscribing to the industry. With the Covid-19 period today, this industry has become one of the opportunities for the people of Konawe Regency to carry out their lives, either by direct subscription or by an online system. This study aims to analyze the elasticity of demand for tempe products in Sendang Mulyasari Village, Tongauna District, Konawe Regency. The analytical tool used in this study is a qualitative descriptive method, which analyzes the data inductively. classified as inelastic, namely the value of d (demand) is greater than 1 (Ed = <1 ). In this type of elasticity, consumers are less sensitive to price changes. That is, even if the price goes up or down, people will still buy it. Suggestions for tempe product producers should consider the factors that affect the elasticity of demand for tempe such as product type, price factor, taste factor, consumer income factor, product availability factor, and product quality.
PENGARUH LEVERAGE DAN PROFITABILITAS TERHADAP MANAJEMEN LABA DENGAN KEPEMILIKAN MANAJERIAL SEBAGAI VARIABEL MODERASI
Authors: Permata Dewi Evia , Nurhayati Ida
Published: September 2022

Penelitian ini meneliti tentang pengaruh leverage dan profitabilitas terhadap manajemen laba dengan kepemilikan manajerial sebagai variabel moderasi pada perusahaan property dan real estate yang terdaftar di Bursa Efek Indonesia periode 2016 hingga 2020. Metode dalam pengambilan sampel adalah purposive sampling. Dimana data yang digunakan adalah data sekunder yang berupa laporan keuangan perusahaan yang terdaftar di BEI selama tahun 2016-2020. Jumlah sampel yang digunakan dalam penilitian ini sebanyak 125 perusahaan. Hasil yang diperoleh dalam penelitian ini adalah leverage dan profitabilitas berpengaruh positif signifikan terhadap manajemen laba. Namun kepemilikan manajerial tidak mampu memoderasi pengaruh leverage dan profitabilitas terhadap manajemen laba.
PENGARUH KUALITAS AUDIT, KOMPENSASI RUGI FISKAL, DAN PERTUMBUHAN ASET TERHADAP TAX AVOIDANCE
Authors: Zulfatin Nihayah Siti , Meita Oktaviani Rachmawati
Published: September 2022

This study was made with the aim of knowing the effect of audit quality, fiscal loss compensation, and asset growth on tax avoidance. What is analyzed is the mining sector with 12 samples of mining companies listed on the Indonesia Stock Exchange in the 2016 to 2020 period, using the purposive sampling method, obtained as many as 60 samples after outlier data. The data source used is secondary data which can be obtained officially on the Indonesia Stock Exchange www.idx.co.id. Data analysis uses panel data regression with E-views 12 software. The results of this study indicate that audit quality has no significant effect on tax avoidance, Fiscal loss compensation has a significant positive effect on tax avoidance, and asset growth has a significant negative effect on tax avoidance.
PENGARUH RASIO KEUANGAN TERHADAP HARGA SAHAM PADA PERUSAHAAN SUB SEKTOR FARMASI DI BURSA EFEK INDONESIA
Authors: Juwari Juwari , Susilowati Dwi , Al Wardah Chairunnisa
Published: September 2022

The purpose of this study was to determine the effect of Price Earning Ratio, Earning Per Share, Return On Equity and Debt To Equity Ratio partially on Stock Prices. In this study, a population of eleven companies and a total sample of seven pharmaceutical sub-sector companies listed on the Indonesia Stock Exchange were taken using the criteria determined by the author. The data analysis method uses is multiple linear regression. The results of the F test are Price Earning Ratio, Earning Per Share, Return On Equity and Debt To Equity Ratio have a significant effect on stock prices in pharmaceutical sub-sector companies listed on the Indonesia Stock Exchange. The results of the t-test is Earning Per Share has a significant effect while Price Earning Ratio, Return On Equity and Debt To Equity Ratio have no significant effect on stock prices in pharmaceutical sub-sector companies listed on the Indonesia Stock Exchange.
PENGARUH CORPORATE GOVERNANCE DAN PENGUNGKAPAN CORPORATE SOCIAL RESPONSIBILITY TERHADAP AGRESIVITAS PAJAK
Authors: Migang Satriawaty , Rivia Dina Winda
Published: September 2022

This study aims to examine the effect of corporate governance and disclosure of corporate social responsibility on the tax aggressiveness of mining companies listed on the Indonesia Stock Exchange in 2015-2019. This study uses 8 sample companies from 38 populations. Tax aggressiveness is proxied using ETR, corporate governance is proxied using independent commissioners, audit committees, and institutional ownership. Corporate social responsibility is measured using CSR disclosure indicators based on the Global Reporting Initiative (GRI) guidelines. The results of this study indicate that corporate governance that is proxied by using independent commissioners and institutional ownership also corporate social responsibility has an effect on tax aggressiveness, while corporate governance that is proxied using audit committees does not affect tax aggressiveness.
Critical Discourse Analysis of Literary Texts of NCTB English for Today (Class II - Class VIII) Textbooks: A Qualitative Study
Authors: Hossain Mohammad Afzal
Published: September 2022

This research has attempted an analysis of the Literary Texts included in the NCTB English for Today (Class II - Class VIII) Textbooks from the perspective of Critical Discourse Analysis (CDA) which is fundamentally a sociolinguistic paradigm to find and locate the internal ideological, social, ethical, moral and political implications encoded in the texts. CDA has been adopted both as a theoretical and methodological framework to carry out the research. Literary texts like poetry, short story etc. have been used as a secondary source materials and data collected from students and teachers from 20 Government primary schools and 10 secondary schools covering 1500 students and 150 teachers as primary data for this research. The primary data has been collected through survey questionnaire and focused group discussion. The collected data has been analyzed using qualitative methods like Content analysis, Narrative analysis, Thematic analysis, Grounded theory (GT) and Interpretive phenomenological analysis (IPA). Various Computer-assisted qualitative data analysis software (CAQDAS) like ATLAS.ti, Dedoose (mixed methods), MAXQDA (mixed methods), NVivo and QDA MINER have been used where necessary to analyze in-depth interviews. The collected data have been analyzed using NVivo software depending on the similarities; the data have been then grouped into categories and themes. These patterned themes have emerged objectively out of the data as emergent themes. The findings from the data shows that 33% of the total student respondents do not at all read the literary texts, 33% of the teacher respondents do not teach or discuss literary texts in the classrooms and only 16% of the students read the literary texts on their own. The literary texts are totally skipped and ignored by around 8% of the student respondents and only 8% of students and teachers read and teach the literary texts effectively as intended. Other results from the data analysis show that majority ..............
Bacteriological Profile of Clinical Isolates from Urinary Samples and Prevalence of CAUTI at a Tertiary Care Hospital
Authors: Tabassum Dr. Samina Kausar , Ahmed Syed Imran , Baig Dr. Mirza Atif
Published: September 2022

Background: Urinary tract infections (UTIs) attributed to the use of an indwelling catheter is one of the most common infections acquired by patients in health care facilities. This infection is associated with varied microbiological etiology. Catheter-associated urinary tract infection (CAUTI) is an important cause of morbidity and mortality in India. The objective of this study was to find the prevalence of CAUTI infection and to determine their antibiotic profile. Aims and Objectives: The aim of the study was to provide a baseline information in the context of culture positivity rate of urinary isolates and prevalence of catheter associated urinary tract infections (CAUTI), to identify the associated microbial, and to determine their susceptibility pattern to commonly used antimicrobial agents for prophylactic and empiric therapy. Materials and Methods: This prospective study was done on nonrepetitive urine samples from all age group patients of both inpatient and outpatient department. Semi quantitative bacterial culture was performed, and isolates were identified and antimicrobial sensitivity tests were carried out by Vitek-2 compact automated method. Results: Significant bacteriuria was observed among 257/1543 (16.65%) urine samples. Among bacterial isolates, Gram negative bacilli predominate. Escherichia coli 7/17 (44%) being the most common isolate followed by Klebsiella (35%). The incidence of CAUTI/1000 catheter days observed in our study was 2.77. Total 3 CAUTI were identified from July 2021 to June 2022, out of which 2 were Klebsiella pneumoniae and 1 isolate was Enterococcus faecium. Conclusions: Uropathogens from CAUTI patients exhibit significantly higher resistance to most antibiotics than non- CAUTI isolates. This is an important factor to take into consideration when choosing correct treatment options for patients with urinary tract infection. Klebsiella pneumoniae is one of the important notable pathogens causing nosocomial infections.............
Atypical hemolytic-uremic syndrome: evolution of treatment and impact of clinical and genetic characteristics on possibility of eculizumab withdrawal
Authors: Prokopenko E. I.
Published: September 2022

Atypical hemolytic uremic syndrome (aHUS) is a rare variant of thrombotic microangiopathy (TMA) associated with uncontrolled activation of alternative complement pathway due to mutations in complement regulatory protein genes or antibodies formation to regulators. Clinical manifestations of aHUS can be triggered by infections, sepsis, pregnancy, autoimmune diseases, organ transplantation, and other complement-activating conditions. Previously, the only treatment option for aHUS was plasma therapy – fresh frozen plasma infusions or plasma exchange, but its effectiveness was insufficient. Currently, targeted treatment available – recombinant monoclonal antibodies against complement C5 protein – eculizumab with high efficiency in achieving aHUS remission, renal function recovery, and preventing TMA at kidney transplantation. For a long time, the question of the optimal duration of treatment and the possibility of eculizumab discontinuing remained unresolved. It was shown that aHUS relapses developed in 20-35 % of patients after discontinuation of complement-blocking therapy. The article presents an overview of a large number of studies of eculizumab treatment outcomes and the possibility of its withdrawal, including a French prospective multicenter study that identified risk factors for aHUS relapse after eculizumab discontinuation: the presence of rare variants of complement genes, female gender, increased soluble C5b-9 plasma level. In patients who did not have rare genetic variants, the risk of relapse was less than 5 %. In general, eculizumab discontinuation after achieving complete remission of aHUS and renal function recovery in patients with low risk of recurrence can provide better tolerability of maintenance treatment, and decrease the incidence of infectious complications and the financial burden on the healthcare system.
Bacteria and viruses in urine in normal and pathology (urobiome and urovirome)
Authors: Kuprienko N. B. , Smirnova N. N.
Published: September 2022

The term "microbiota" refers to a group of bacteria, as well as viruses, protozoa, fungi, and archaea associated with a specific niche of macroorganism. In recent years, interest in the viral component of the microbiota, virome, has increased. The gut microbiome is best studied. The study of the microbiome and urine virome and urinary organs has just begun. The review presents data on eukaryotic viruses and bacteriophages in the urinary system organs under physiological and pathological conditions. In the future, the study of urobiome and urovirome will allow revising approaches to therapy of nephro-urological pathology.
The role of ВKСа and IKСа channels in H2S-induced dilatation of pial arteries in rats after nephrectomy
Authors: Sokolova I. B. , Ivanova G. T.
Published: September 2022

BACKGROUND. Chronic kidney disease (CKD) is accompanied by the development of endothelial dysfunction, leading to a decrease in arterial reactivity to vasoactive agents. Uremia causes a change in the dilatation of arteries in various vascular regions, incl. and arteries of the pial membrane of the brain. The action of hydrogen sulfide (H2S), which can induce relaxation of smooth muscle cells of blood vessels, is currently considered a possible route of vasoprotection in various diseases, particularly, in CKD. THE AIM. To evaluate the role of calcium-activated potassium channels of large (BKCa) and intermediate (IKCa) conductance in H2S-induced dilatation of pial arteries in nephrectomized (NE) rats.

   MATERIAL AND METHODS. In Wistar rats nephrectomy (NE) was performed by resection of 5/6 of the renal tissue mass. Sham-operated (LO) animals served as control. The reaction of the pial arteries of the sensomotor cortex of NE and control SO rats to the application of H2S under physiological conditions and against the background of the use of BKCa channel blockers – tetraethylammonium (TEA) and IKCa – channels – TRAM-34.

   RESULTS. 4 months after NE, the application of H2S led to the dilatation of a smaller number of pial arteries (1.4 – 1.7 times) compared with SO rats. The preliminary exposure to TEA led to a decrease in the number of pial arteries responding by dilatation to the action of H2S in NE and SO rats. Against the background of the action of TRAM-34, the number of dilated arteries decreased under the action of H2S in SO rats, while in NE rats it practically did not change.

   CONCLUSION. Under physiological conditions, dilatation of the pial arteries in rats under the action of H2S is realized (at least in part) through the activation of the BKCa and IKCa channels of the membrane of endothelial and smooth muscle cells. Uremia, caused by nephrectomy, leads to impairment of the mechanism of dilatation of pial arteries, mediated by activation of calcium-activated potassium channels intermediate conductance apparently due to dysfunction of endothelial cells.
Case report of primary membranous nephropathy associated with muscle and peripheral nerve damage
Authors: Kochoyan Z. Sh. , Bystrova O. B. , Dobronravov V. A.
Published: September 2022

Primary membranous nephropathy (PMN) typical cause of nephrotic syndrome in adults. The key point in its pathogenesis is the production of IgG4 subclass autoantibodies (IgG4) against podocytic transmembrane phospholipase A2 M-type receptor (anti-PLA2R), followed by the deposition of subepithelial immune complexes (IC) in situ. We present a case of a 37-year-old young man with PMN associated with demyelinating polyneuropathy and idiopathic inflammatory lesions of skeletal muscles demonstrating a possible variant of extrarenal effects of IgG4-anti-PLA2R with an extended analysis of diagnostics and probable mechanisms of imbalance of secreted and intracellular phospholipases.
Analisa Penerapan Program Keselamatan Kerja Dalam Meningkatkan Produktivitas Kerja Dengan Pendekatan Fault Tree Analysis Di PT Hasil Sembako Cipta
Authors: Andayansyah Lucky
Published: September 2022

PT. Hasil Sembako Cipta dalam pengoperasiannya tidak luput dari masalah- masalah yang dihadapi seperti adanya kecelakaan kerja, penyakit akibat kerja dan dampak negatif industri terhadap lingkungan sekitarnya, maka Pencapaian produktivitas yang optimal memerlukan tingkat keselamatan manusia sebagai faktor produksi. Pelaksanaan Program Keselamatan dan Kesehatan Kerja merupakan proyek pendukung yang sangat penting dalam kegiatan produksi.  Program  keselamatan  kerja terdiri dari beberapa unsur program dan pendukungnya. Dalam hal ini penulis berangkat dari menurut  International Labour Organization (ILO). Dalam studi ini, kami mengukur T-score untuk kesehatan dan keselamatan kerja. Ini adalah pengukuran frekuensi yang menunjukkan jumlah kecelakaan yang terjadi per 1 juta jam kerja selama periode berjalan.. Tingkat keparahan menunjukkan jumlah hari hilang terkait kecelakaan per 1.000.000 jam kerja dari "jam kerja" karyawan. Nilai T selamat merupakan indeks yang bertujuan untuk membandingkan hasil tingkat pengurangan kecelakaan yang dicapai dalam pekerjaan. Dari pelaksanaan program kesehatan kerja pada PT. HSC bisa dikatakan telah terlaksana cukup baik. Kecelakaan yang terjadi pada tahun 2019-2021 adalah 10, 7, 3 kali kecelakaan. Dengan tingkat frekuensi dari tahun 2019-2021 adalah 44,3; 39,9; 13,5. tingkat keparahan yang terjadi pada tahun 2019-2021 adalah 1.552,4; 395,2; 94,6. Nilai T Selamat tahun 2020 diketahui –304,75 dan pada tahun 2021 sebesar –1.968. Semakin menurunnya tingkat kecelakaan dan tingkat keparahan kecelakaan dari tahun ketahunnya maka akan meningkatkan produktivitas tenaga kerja
Sistem Informasi Pengaduan Dan Edukasi Hukum Terkait Dengan Kekerasan Anak Dan Perempuan Berbasis Internet
Authors: Dewi Dahlia Kusuma
Published: September 2022

Pada zaman sekarang, internet sangat memudahkan segala pekerjaaan penginputan data dan membuatnya menjadi sangat mudah, terlebih dengan sistem ini yang bertujuan memberi gambaran tentang pengertian penginputan data online, cara memulai menginput, pangaduan online, edukasi online, dan berbagai macam penginputan online yang bisa dilakukan, menjadi semakin mudah dilakukan. Bila biasanya menginput data masih dilakukan secara manual atau menginput data-data secara offline, maka dengan internet semua dapat dilakukan dengan mudah dan tidak perlu repot lagi untuk menginput data korban KDRT yang terjadi. Hanya dengan cara menginstal software aplikasi, korban KDRT ataupun Masyarakat khususnya Perempuan dapat mengadukan kasus KDRT yang dialaminya ataupun Perempuan khususnya Ibu Rumah Tangga bisa mengetahui hukum khususnya tentang Kekerasan Dalam Rumah Tangga atau biasa disebut dengan KDRT. Dan dari registrasi pengguna atau disebut dengan user, maka akan didapat dengan mudah data-data kasus korban KDRT. Dan untuk keamanan file atau data yang diterima dari user akan terjamin.
Fetal Non-reaktif non-stress test paterni takibinde fetal doppler ultrason veya çikolatanın yeri : Prospektif randomize kontrollü çalışma
Authors: KARAKOÇ Gökhan , YALÇIN Serenat , EROGLU Hasan , ŞEN SELİM Halime , KURT Kutlu , ŞENGÜL Mustafa , YÜCEL Aykan
Published: September 2022

Aim: The aim of this study is to compare the effect of 20-second MCA Doppler ultrasonography and bitter chocolate on non-stress test (NST) patterns, fetal movements felt by the mother and cesarean delivery rates.

Methods: Single pregnancies between 36-41 weeks with non-reactive NST pattern were included in the study and prospectively randomized to Doppler ultrasound, bitter chocolate, and non-intervention control groups. NSTs of the patients at the 5th and 30th minutes were examined.

Results: The rate of improvement in the fetal movements felt by the mother did not differ significantly among groups (p ˃ 0.05). The 5th minute reactive NST ratio in the Doppler group was significantly higher (p ˂ 0.05) than in the follow-up and chocolate group. In the chocolate and non-intervention control group, the 5th minute reactive NST ratio did not differ significantly (p ˃ 0.05). In the 30th minute NST, patients with non-reactive results had significantly higher fetal distress rates in the Doppler group compared to the other groups (p ˂ 0.05).

Conclusions: We think that with the application of Doppler, the length of hospital stay and accordingly patient’s anxiety will reduce. In addition, the patient should be monitored more carefully in terms of fetal distress because it quickly corrects false non-reactivity.
The Relationship Between Urinary Incontinence and Sarcopenia in Patients with Dementia
Authors: DOST Fatma Sena , GÖKDENİZ YILDIRIM Açelya , ATEŞ BULUT Esra , AYDIN Ali Ekrem , IŞIK Ahmet Turan
Published: September 2022

Aim: Dementia, sarcopenia, and urinary incontinence (UI) are common geriatric syndromes. UI is a condition that affects the quality of life, results in social isolation, causes falls and, causes morbidity and mortality due to falls. UI also increases caregiver burnout and the burden of care in dementia patients. Continence requires an intact genito-urinary system, peripheral and central nervous system, and cognitive health. In addition, the importance of the pelvic floor muscles from the striated muscle group and the skeletal system in continence cannot be ignored. In the light of these facts, we aimed to evaluate the relationship between UI and sarcopenia in patients with dementia.

Materials and Method: Dementia patients with sarcopenia who applied to the DEU Geriatrics unit between January 2015 and December 2021 were included. Patients with CDR 3 dementia and those with acute problems were excluded. Patients were grouped according to their UI status and evaluated for sarcopenia using the EWGSOP-2 criteria.

Results: According to the presence of UI, no significant difference was found in demographic and laboratory findings between groups. The frequency of anti-parkinsonian drug usage and depression was more common in the UI group. While, the frequency of probable sarcopenia, severe sarcopenia, slow gait speed, and frailty was higher in the UI group; Barthel's score was lower (p
Kryoballon ile Tek Merkezde Atriyal Fibrilasyon Ablasyonu Deneyimi
Authors: KÜP Ayhan , ÇELİK Mehmet , ÖZGEYİK Mehmet , DEMİR Serdar , GÜLŞEN Kamil , AKGÜN Taylan , USLU Abdulkadi
Published: September 2022

Background: Electrical isolation of the pulmonary veins is known as the fundamental of for atrial fibrillation (AF) treatment invasively, and thus, has been suggested as the first-line therapy in AF curation. In this study, we presented our single center pulmonary vein isolation (PVI) experience and long-term clinical outcome.

Methods: One hundred and six symptomatic AF patients resistant to medical therapy underwent cryoablation of the pulmonary veins. Participants were divided into two groups regarding AF categorization as persistent or paroxysmal. Recurrence and peri-procedural complications were evaluated after the treatment.

Results: A 106 patients, 67 males (63.2%), with mean age of 51.8 ±13.1 years, underwent cryoablation. While the paroxysmal AF group was composed of 90 patients (84.9%); the persistent AF group consisted of 16 patients (15.1%). The procedure mean time was 115,9±9,1 minute while the fluoroscopy mean time was 29,2±5,6 minutes. A total of 8 (7.5%) non-fatal complications were experienced. A total of 18 recurrences (17%) were observed during mean duration of 25.2 months follow-up period. The survival rates without AF were 85.6% and 61.8 % in in the paroxysmal and persistent groups, respectively.

Conclusion: The cryoballoon PVI seems to be a successful and reliable method of treating AF and may be preferred as a primary procedure even in patients with persistent AF.
Kuru iğneleme ile ilgili Youtube videolarının kalitesinin ve geçerliliğinin değerlendirilmesi
Authors: ULUTATAR Firat , UNAL ULUTATAR Cagri
Published: September 2022

Objectives: With the popularization of the Internet, social media platforms are used frequently as an information source. Patients can watch YouTube videos and gather information on dry needling especially before the procedure. This cross-sectional study aimed to assess the reliability and quality of videos on dry needling.

Materials and Methods: A search was conducted on YouTube using the keyword “dry needling”. Features of videos, such as the number of views and duration of the videos, were noted. The reliability and quality of videos were assessed with the DISCERN and the Journal of the American Medical Association (JAMA).

Results: A total of 150 videos were screened and 50 videos were excluded: 30 were duplicates, 10 were off-topic, 5 were in a language other than English, and 5 had no audio. Most of the videos were uploaded by non-physician health personnel (42%) and physicians (27%). The most common video content was demonstration (53%) of dry needling. The mean scores of the JAMA and DISCERN tools were 1.9 and 35.3, respectively. Thirty-four percent of videos were very poor, 31% were poor, 18% were fair, 11% were good, and only 6% were excellent.

Conclusion: YouTube is a platform where medical information is freely shared and widespread. In this study, we found that most of the YouTube videos on dry needling were of low quality. Future efforts by healthcare professionals and academic institutions are necessary to improve the reliability and quality of medical information on dry needling.
GASTROİNTESTİNAL PERFORASYON TANISINDA KULLANILAN GÖRÜNTÜLEME YÖNTEMLERİ VE GÖRÜNTÜLEME BULGULARI
Authors: ILGAR Mehtap , ŞAHİN Tuna
Published: September 2022

Purpose: To evaluate the imaging methods used in patients diagnosed with gastrointestinal perforation (GIP) and the contribution of these methods to the diagnosis.

Methods: Preoperative radiological examinations of 73 patients 18 years old or older whose surgical results indicated GIP were retrospectively evaluated. The perforation sites were divided into 4 groups, namely the first segment of the gastroduodenum, part of the small intestine beginning with the second segment of the duodenum, the colorectum, and the appendix. Esophageal perforations were considered as a separate group and excluded from the study.

Findings: Fifty-two (71.2%) of the patients were male. The mean age of the patients was 45.1±18.2 years with a range of 18-87 years. Forty (54.8%) patients had perforations of the appendix and 25 (34.2%) patients had perforations of the gastroduodenum. Computed tomography (CT) was performed in 56 (76.7%) of the patients, ultrasonography (USG) in 55 (75.3%), and radiography (RG) in 48 (65.8%). The evaluation of RG images of the patients for the presence of subdiaphragmatic free air showed that 50% of the patients with non-appendix perforations had subdiaphragmatic free air. The most common findings in the USG results of the patients with appendix perforations were an increase in the diameter and heterogeneity of mesenteric fatty tissue, while the most common USG finding in the patients with the other perforations was free fluid. The site of perforation was accurately determined in 83.9% of the patients diagnosed with non-appendix perforations by CT.

Conclusion: CT is the most preferred imaging modality and has the most diagnostic value in the diagnosis of GIP. It is also useful in determining the perforation site.
Ratlarda Rosmarinik Asit’in Akut Pankreatit Üzerindeki Koruyucu Etkinliğinin İncelenmesi
Authors: RENCBER Memet , OĞUZ Abdullah , YİLDİZHAN Eda
Published: September 2022

Abstract

Aim: Acute pancreatitis is a serious disease, with an incidence of 5 - 35 in 100,000 individual. New studies are constantly planned for the treatment of pancreatitis. Many studies have shown that Rosmarinic acid has antioxidant properties. In this study, we examined the protective effect of Rosmarinic acid on acute pancreatitis.

Material and Methods: A total of 28 animals were used during the experiment, and 4 groups were formed with 7 animals in each group. Group 1 is the control group. The rats in Group 2 were administered 75 μg/kg Cerulein every hour intraperitoneally at one hour intervals, a total of four times. Group 3 experimental animals were given 50 mg/kg Rosmarinic acid by per oral gavage. The rats in group 4 were given 50 mg/kg Rosmarinic acid per oral gavage after 75 μg/kg Cerulein was injected intraperitoneally every hour for a total of four times. Afterwards, all animals were sacrificed by exsanguination, blood samples and pancreatic tissue were taken for examination.

Results: Examination of pancreatic tissues revealed necrosis, edema and inflammation in the acute pancreatitis group. Both histopathological and serum values of the rosmarinic acid group were close to the control group. The use of Rosmarinic acid after acute pancreatitis had a positive effect on the pacreatic tissues and blood values, but still did not cause complete recovery.

Conclusion: In the case of acute pancreatitis, it was concluded that rosmarinic acid has a partial curative effect, but still does not provide a full recovery.
Erişkin Dönemin Nadir Görülen Beyin Tümörü: Medulloblastom Tanılı 28 Hastanın Demografik Özellikleri
Authors: KÖŞECİ Tolga , ATA Serdar , SEYYAR Mustafa , OLGUN Polat , BAYRAM Ertuğrul , ESER Kadir , TAŞ Zeynel Abidin
Published: September 2022

Amaç: Medulloblastom çocukluk çağında sık görülen beyin tümörlerinden biridir. Erişkin yaşta ise çok nadir olarak görülmektedir. Bu çalışmamızda medulloblastom tanılı hastalarımızın klinik ve patolojik özelliklerini paylaşmayı amaçladık

Yöntemler: 2010 Kasım ile 2020 Nisan ayı arasında medulloblastom tanısı alan 28 hasta çalışmaya dahil edilmiştir. Hasta dosya sistemin-den yaş, cinsiyet, tanı tarihi, ex tarihi, progresyon tarihi, tümör lokalizasyonu, tümör histopatolojik alt tipi, cerrahi şekli verileri kaydedildi. Hastaların 5 yıllık ortalama sağkalım ve progresyonsuz sağkalım oranları hesaplandı.

Bulgular: Hastaların ortalama yaşı 32 idi. 16 hasta erkek 12 si ise kadındı. Histopatolojik özelliklerine bakıldığında 17 hasta klasik varyant, 11 hasta ise desmoplastik histopatolojiye sahipti. 15 has-tada nüks saptanırken 13 hasta nüks bulgusuna rastlanılmadı. 28 hastanın 16’sı yaşıyor 12 hasta ise ex olmuştu. Hastaların 5 yıllık OS %59,4, 5 yıllık PFS ise %42,3 idi

Sonuç: Medulloblastom erişkin dönemde çok nadir olarak görüldüğü için bu hastalık ile ilgili yeterli veri bulunmamaktadır. Komplet rezeksiyon bu hastalarda sağkalım açısından büyük önem içermektedir.
Obez Kişilerde Tıkanırcasına Yeme Ataklarının Şiddetinin Azaltılması
Authors: BELİBAĞLI Mehmet Cenk
Published: September 2022

Aim: The study aimed to analyze the change in the severity of binge eating disorder in obese individuals registered to the Adana City Training and Research Hospital Obesity Center training program.
Methods: The study was a single-arm, prospective, quasi-experimental study with an interrupted time-series design. Inclusion criteria were having registered to the center for training, age between 18 to 65 years, a body mass index (BMI) equal to or over 30 and having binge eating disorder. Binge eating disorder evaluation (BEDE) was a structured form exclusively using DSM-5 binge eating disorder (BED) diagnosis and the severity criteria. The progress record included a weekly curriculum that a physician, dietitian, psychologist administered, and the physiotherapist and the monthly individual meetings data.
Results: The BEDE reports showed a significant improvement, with 65 of the patients scoring below the BED diagnosis at the final evaluation. There was no difference between the genders regarding improvement in episodes. The current study showed that after twenty weeks of training that lasted for approximately 80 hours, the patients reported fewer episodes.
Conclusions The training could be considered efficacious for reducing the severity of binge eating episodes in obese patients seeking treatment.
Yaşlı hastalarda perkütan nefrolitotominin etkinliği ve güvenilirliği: 128 vaka deneyimi
Authors: KARKİN Kadir , VURUŞKAN Ediz
Published: September 2022

OBJECTIVE: This study aimed to evaluate the efficacy and safety of percutaneous nephrolithotomy in elderly patients (≥65 years) with kidney stones > 2 cm in size.

PATIENTS AND METHODS: Patients aged ≥65 years who underwent percutaneous nephrolithotomy for kidney stones between January 2015 and January 2022 were included in this study. Patient profiles, preoperative stone data, operative information, and postoperative complications were reviewed. We applied the Guys Stone score to predict the net results of percutaneous nephrolithotomy.

RESULTS: Percutaneous nephrolithotomy was performed on 128 geriatric patients. Of these patients, 68 (53.1%) were male and 60 (46.9%) were female. The mean age was 69.87 ± 7.06 (65–80) years. The mean stone size was 28.7 ± 6.5 mm (22–46 mm). The mean operative time was 90.33 ± 40.56 min and fluoroscopy time was 5.16 ± 2.81 min. The reentry catheter was removed after an average of 3.21 ± 1.82 days. The mean duration of hospital stay was 3.17 ± 2.19 days. The stone-free survival rate was 90.6%. Transfusion was performed in four (3.1%) patients due to hemorrhage, and urine extravasation from the re-entry tract occurred in eight (6.2%) patients, and this required Double j-stent placement. When the four Guys stone score groups were compared, there was a statistically significant difference in stone-free rates (p = 0.001).

CONCLUSIONS: According to our results, percutaneous nephrolithotomy is a safe and effective treatment option for nephrolithiasis in the elderly, with high stone-free and acceptable complication rates.
Smoking and respiratory allergic diseases
Authors: Devyatkova Elizaveta A. , Minaeva Nataliia V. , Tarasova Mariya V.
Published: September 2022

This review presents a modern view on the problem of the impact of smoking on allergic respiratory diseases. Smoking is known as a significant risk factor for asthma. Currently, studying the effect of smoking on allergic rhinitis and sensitization to allergens is of scientific interest. Tobacco smoke affects the mucous membranes of the respiratory tract, contributing to a change in structure and dysfunction, and it can increase the activation of the Th2-immune response and the production of IgE when simultaneously exposed to allergens, which may contribute to the development of allergic diseases.
In recent years, electronic cigarette smoking has become especially popular. The aerosol components of electronic cigarettes are characterized by irritant properties and inhalation toxicity. Smoking electronic cigarettes, like smoking traditional cigarettes, can affect the immunity of the respiratory mucosa, including the functions of epithelial cells, macrophages, and neutrophils.
This article presents conflicting data on the effect of smoking on allergen sensitization. Tobacco smoke is a known trigger, and its exposure increases the risk of developing new cases of asthma in patients with allergic rhinitis. However, the influence of smoking on the development and clinical course of allergic pathology requires further study.