bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Kesulitan Belajar dengan Menggunakan Model Giving Question and Getting Answer
Authors: Siagian Meryance Viorentina , Fau Alwin
Published: December 2021

Kesulitan belajar yang dialami mahasiswa merupakan suatu kondisi yang berdampak pada kemampuan pribadi mahasiswa tersebut dalam menguasai tujuan pembelajaran yang hendak dicapai. Berdasarkan studi pendahuluan kesulitan belajar yang dialami mahasiswa masih sangat rendah, karena di dalam pembelajaran pada masa covid-19 ini, interaksi antara dosen dan mahasiswa sangat sulit, terlebih dalam menggunakan media pembelajaran elektronik. Tujuan penelitian ini yaitu untuk menganalisis kesulitan belajar yang dialami mahasiswa dengan menggunakan model giving question and getting answer sebagai aplikasi pembelajaran. Penelitian ini merupakan penelitian kualitatif dengan menggunakan metode penelitian deskriptif. Pelaksanaan penelitian ini dilakukan kepada mahasiswa Universitas Budi Darma Tahun Ajaran 2020/2021. Pengumpulan data untuk penelitian ini berupa hasil observasi, tes dan wawancara. Hasil penelitian menunjukkan bahwa model giving guestion and getting answer sebagai aplikasi pembelajaran dapat membantu meningkatkan hasil belajar mahasiswa yang lebih baik serta membantu mempermudah mahasiswa memahami matematika dalam proses pembelajaran di Perguruan Tinggi.
Bioinformatics analyses on molecular pathways and pharmacological properties of Glabridin
Authors: GEZİCİ Sevgi , ŞEKEROĞLU Nazım
Published: December 2021

Glabridin, a bioactive compound that originally isolated from the roots of licorice (Glycyrrhiza glabra L., Fam. Fabaceae), has a wide range of pharmacological properties for instance anti-inflammatory, anti-cancer, anti-microbial, anti-viral, anti-osteoporosis, anti-diabetic, anti-atherogenic, neuroprotective, estrogenic, and skin-whitening. Even though, biological activities and pharmacological properties of glabridin have already been determined, molecular signaling pathways, gene targets, and pharmacological properties based on bioinformatics analyses have not been fully elucidated. Thus, in the presented research, network-based bioinformatics approaches were applied to demonstrate targets of glabridin in human genomes and proteomes. The glabridin was input into the ChEBI database, and the targets of its were predicted using DIGEP-Pred, and then, top interacting genes were identified by GeneCards database. Afterward, STRING and KEGG enrichment database were used to construct a protein-protein interaction (PPI) network and molecular targeting pathway network, respectively. A total of 14 genes coding proteins such as UGT1A1, MAPK1, CYP2B6, MMP9, CHKA, CYP3A4, EGFR, PON1, SLC6A4, SRC, EPHX2, TYR, PTK2, and PPIG effected by glabridin were determined by gene set enrichment analysis. Furthermore, multiple pathways including endocrine resistance, bladder cancer, ErbB signaling pathway, VEGF signaling pathway, chemical carcinogenesis, proteoglycans in cancer, relaxin signaling pathway, and estrogen signaling pathway were also identified to be regulated by glabridin. This research showed that glabridin exhibits highly active pharmacological activity as an anti-infective agent, chemopreventive agent, membrane permeability inhibitor, melanin inhibitor, and apoptosis agonist. Taken together, this study is network-based scientific research that will be very useful in elucidating the biological, molecular and pharmacological properties of glabridin for clinical applications in detail.
Resource use efficiency and economies of scale for ginger production in Ilam district, Nepal
Authors: SHRESTHA Anish , DHAKAL Shiv , MARAHATTA Santosh , KOİRALA Ankit
Published: December 2021

This study was conducted in the Ilam district of Nepal to analyse resource use efficiency and economies of scale of ginger farming. A total of 160 farmers and 20 traders (collector, wholesaler and retailers) from the study area were randomly selected as the sample. The pre-tested systematic questionnaire, fitted in KoBo Toolbox, was used to obtain the primary data through face to face household interviews. The production function of ginger farming was in increasing return to scale, with a score of 1.1356. The result showed that expenditure on seed and labour was over utilised. Except for these two, other inputs of ginger farming were underutilised. Economies of scale for ginger production was 44 quintal in production quantity and 5.68 ropani (1 hectare=19.66 ropani) in area. To obtain economies of scale, ginger production and size must be increased by around double the present context. The study concluded that to increase the profitability of ginger farming, resources must be utilised in optimum conditions, and production scale must be increased.
A first insight into genetic diversity of Jerusalem artichoke accessions collected from different regions of Turkey assessed by ISSR markers
Authors: HANCI Fatih
Published: December 2021

The study aimed to assess genetic diversity among Jerusalem artichoke (Helianthus tuberosus L.) accessions using ISSR (Inter Simple Sequence Repeat) markers. Twenty-five Jerusalem artichoke accessions collected from the different regions of Turkey have been used for molecular analysis. Nine primers used in the study produced a total of 62 bands. A total 57 of these are polymorphic. 57 of them resulted in polymorphic. Allele's average number was 6.33. Polymorphic information content (PIC) varied between 0.219 and 0.340. Examined accessions were classified into two main groups in a dendrogram. Genetic similarities varied from 0.001 to 0.815, with an average of 0.292. Also, Principal Coordinate Analysis (PCoA) of molecular data was conducted. These findings present valuable diversity data for recognizing the Jerusalem artichoke germplasm, preserving genetic richness, and determining parents for genetic enhancement.
A EDUCAÇÃO AMBIENTAL E A INSERÇÃO DA PEDAGOGIA DE PROJETOS NO AUXÍLIO DA PRÁTICA DOCENTE, PARA O INCENTIVO A PRÁTICA DA PESQUISA NA FORMAÇÃO DISCENTE NA ESCOLA “INSTITUTO IMACULADA CONCEIÇÃO”, NO MUNICÍPIO DE BAIÃO, NO PERÍODO DE 2018
Authors: GONÇALVES RAMOS ENÉAS
Published: December 2021

Este trabalho buscou analisar como a Educação Ambiental vem sendo implementada no espaço escolar e quais seus avanços e desafios na prática do docente em uso de metodologias de ensino sobre a aplicabilidade de projetos que estimulem a pesquisa de campo. A pesquisa foi norteada pelas questões indagativas, que direcionaram o trabalho do pesquisador no campo de investigação buscando evidenciar. Como ocorre a inserção da Pedagogia de Projetos pelos educadores nas aulas de Educação Ambiental, na formação do pensamento crítico do discente? Como a prática docente, está sendo aplicada para o incentivo pesquisa de campo na formação da consciência ambiental do discente? De que maneira a Educação Ambiental na Escola “Instituto Imaculada Conceição”, vem sendo aplicada pelos docentes? A metodologia utilizada foi o estudo Misto com desenho DITRAS, tendo o enfoque Misto direcionado pelo alcance exploratório descritivo. O estudo teve os seguintes objetivos: Relatar a inserção da Pedagogia de Projetos pelos educadores nas aulas de Educação ambiental, na formação do pensamento crítico do discente. Identificar como a prática docente, está sendo aplicada para o incentivo pesquisa de campo na formação da consciência ambiental do discente. Definir a maneira que a Educação Ambiental na Escola “Instituto Imaculada Conceição”, vem sendo aplicada pelos docentes. Em termo da hipótese se deu a constatação da hipótese Investigativa Afirmativa ao afirmar de maneira contundentemente que a inserção da Pedagogia de Projetos no auxílio da prática docente, é uma ação positiva para o incentivo à prática da pesquisa na formação da criticidade do discente no ensino da Educação Ambiental na Escola “Instituto Imaculada Conceição”, no Município de Baião, no período de 2017. Em termo da hipótese se deu a constatação da hipótese Investigativa Afirmativa ao afirmar de maneira contundentemente que a inserção da Pedagogia de Projetos no auxílio da prática docente, é uma ação positiva para o incentivo à prática da pesquisa na formação da criticidade do discente no ensino da Educação Ambiental na Escola “Instituto Imaculada Conceição”, no Município de Baião, no período de 2017.
ESTIMATION OF THE SAFETY OF LOW-INTENSITY LASER RADIATION IN TREATMENT OF PATIENTS WITH PROFESSIONAL POLYNEUROPATHIES OF THE UPPER LIMBS
Authors:   North-Western State Medical University named after I.I. Mechnikov, St Petersburg, Russia, Grebenkov S.V. , Malkova N.Y. , Kochetova O.A. ,   North-West Public Health Research Center, St Petersburg, Russia
Published: December 2021

Abstract: The inclusion of low-intensity laser radiation in the complex treatment of professional polyneuropathies of the upper extremities, due to its numerous biological effects, contributes to a statistically significant reduction in pain in the hands of patients, and improves the conduction of nerve impulses along the peripheral nerves of the hands. In addition to describing the positive clinical and neurophysiological trends achieved during treatment, the issue of the safety of the developed therapy method is important. The aim of the study is to assess the safety of the proposed method of low-intensity laser therapy (LILT) in patients with professional polyneuropathies of the upper extremities. Material and methods: on the basis of the department of occupational pathology, 116 patients (60 men, 56 women) with occupational polyneuropathies of the upper extremities were treated using LILT. Therapeutic measures were carried out using a semiconductor laser apparatus for red spectrum radiation (650 nm) with fiber-optic light guides for percutaneous therapy "ALP-01-Laton" in the sitting position of patients. Diffuse scattered laser radiation of the red region of the spectrum with an energy illumination of 0.7-1.1 mW / cm2 directly affected the projection area of the exit of the median nerve from the carpal tunnel to the hand. There were 5-10 procedures per course, the energy exposure of laser radiation and the number of sessions were determined individually. Results: To ensure the safety of the therapy, patients were included in the study strictly in accordance with the developed inclusion and non-inclusion criteria. Patients were treated in a specially equipped room with the use of personal protective equipment; safety rules were followed during the operation of the device. During treatment, all 116 patients treated with LILT did not have systemic side effects. A number of patients developed short-term complaints associated with local reactions: short-term tingling sensations and "goose bumps" in the hands, warmth, slight burning sensation, etc. All recorded local side effects occurred directly during LILT-procedures and were completely stopped within 1-5 minutes after their completion. In general, LILT-exposure did not cause serious side effects and was well tolerated by patients. 13.5% of patients noted a decrease in pain in the arms directly during the LILT treatment procedures. Conclusion. The developed method of LILT of professional polyneuropathies of the upper extremities is simple and convenient for use in clinical practice: it is applicable both in a hospital and on an outpatient basis. LILT has a limited list of contraindications, and is generally well tolerated by patients with minimal local side effects.
FEATURES OF THE HUMANS’ THERMAL STATE WHEN USING A PERSONAL PROTECTIVE EQUIPMENT AGAINST POWER-FREQUENCY ELECTRIC FIELDS
Authors:   FSBSI «Izmerov Research Institute of Occupational Health», Moscow, Russia, Gusarova M.V. , Malakhova I.S. , Burmistrova O.V.
Published: December 2021

Abstract. Introduction. When using personal protective equipment (PPE) against power-frequency electric fields (PFEF), there is a problem associated with the deterioration of the humans thermal state during a workshift when working in a hot environment. The shielding and shunting elements of the PPE increase the weight of the PPE and has an additional thermal load on a person working in a hot environment and so have a negative impact on his thermal state. The change in the indicators of the persons’ thermal state can be considered as a criteria for the impact of a complex of factors that determine the body heat exchange with the environment. Also, in addition to the impact of the PFEF and the hot environment, workers are exposed to physical exertion associated with moving around the area and lifting weights, which additionally burdens their functional state. Purpose. To study the thermal state of a person using PPE from the PFEF, when performing physical work at different thermal load levels of the environment. Materials and methods. Four practically healthy men were involved as volunteers. Before and after the experiment, the initial skin temperature indicators were recorded in 11 areas of the body surface as well as the tympanic membrane temperature and the heart rate (HR). During physical activity and rest, subjective heat and humidity sensations were also recorded every 5 minutes on the 11 areas of the body surface and the temperature of the inner surface of the clothing was determined. Before and after the experiment, the body weight of the naked volunteer and the weight of all the items included in the PPE kit were recorded. Results and discussion. During physical work at WBGT 28.0°C, ΔQts reached the permissible level (2.6 kJ/kg) after 10 minutes from the start of the work, and when working in WBGT 23.3°C – after 20 minutes, which indicated the highest rate of overheating of the human body at a higher level of the thermal load. The moisture sensitivity score at WBGT of 28.0°C by the end of the working period was 3.3. Stabilization of the HR was observed at a lower level of the thermal load, but at WBGT 28.0°C there was a HR continuous increase, which indicates a greater tension of the thermoregulation mechanisms. Conclusion. The obtained data allowed us to establish the fact of the negative impact of the use of EP-4(0) kits on the humans’ thermal state. When using the EP-4(0), it is necessary to regulate the time of continuous work in the open air: no more than 2 hours with a subsequent rest for at least 30 minutes in order to compensate heat loss as a result of using such PPE, which hinders heat and moisture exchange.
MODERN CHALLENGES AND TECHNOLOGIES FOR MAINTAINING THE HEALTH OF DENTISTS IN THE FACE OF NEW OCCUPATIONAL RISKS CAUSED BY CORONAVIRUS INFECTION
Authors:   FGBOUVO «St. Petersburg State University», Danilova N.B. , Nekhoroshev A.S. ,   North-Western State Medical University named after I. I. Mechnikov, Pavlova S.G. ,   FGBOUVO «St. Petersburg State Pediatric Medical University» of the Ministry of Health of the Russian Federation
Published: December 2021

Abstract: The monitoring of the activities of dentists in the context of the continuing high risk of the spread of a new coronavirus infection from the point of view of occupational medicine made it possible to identify a number of key points that distinguish the work of dental doctors at the moment. Working in a mode of increased epidemiological danger is a factor that aggravates the neuro-emotional stress of doctors; the predominant use of chlorine-containing agents for cleaning and disinfection leads to an increase in the concentration of chemically active substances in the air of the working area and causes a deterioration in performance, can be the cause of specific, acute, subacute and chronic poisoning; changing the vector of using modern personal protective equipment (special protective suits, respirators, gloves, eye protection), solving issues of continuous updating of the knowledge of dentists on labor protection issues; an increase in the workload of working hours due to the collection and analysis of the patient's epidemiological history, and, as a consequence, a decrease in the possibility of rational use of work breaks aimed at preserving the health of dentists.
TO THE QUESTION OF INDUSTRIAL AEROSOL CONTROL IN THE PROCESSING OF BLISTER COPPER
Authors:   Yekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Yekaterinburg, Russia, Drugova O.G. , Fedoruk A.A. , Shtin T.N.
Published: December 2021

Abstract. Due to the predominance of PM1 particles in the air samples, the following metals were found in the aerosol: copper, zinc, silicon, iron, lead, sulfur, arsenic, aluminum, antimony, tin, magnesium, cadmium and several other metals. The content of sulfates was significantly noted. These physical and chemical properties show a considerable toxic potential of industrial aerosol. The MPC of lead, sulfur and silicon dioxides, as well as nitrogen oxides and formaldehyde were detected in the working air. Meanwhile, copper, zinc, and iron did not exceed their MPC. Moreover, an underestimation of the aerosol was observed within the framework of industrial control. It has been found that the aerosol components may have an irritating, reprotoxic, allergenic, and carcinogenic effect on the body. Further consideration of the dispersed and chemical composition of the aerosol is required to determine the concentration of identified substances in the working air and the limiting components determining its biological effect.
STUDY OF THE ATTITUDE TO HEALTH AND HEALTHY LIFESTYLE OF RAILWAY WORKERS
Authors:   Central Directorate of Healthcare – the branch of Joint Stock Company «Russian Railways», Moscow, Russia, Zhidkova E. ,   FSBEI HE «A.I. Yevdokimov Moscow State University of Medicine and Dentistry» of the Ministry of Healthcare of the Russian Federation, Moscow, Russia, Gutor E. , Gurevich K.
Published: December 2021

Abstract: The aim of the study is to identify risk factors that increase the likelihood of chronic non-communicable diseases in railway workers, as well as the state of conditions for employees to lead a healthy lifestyle. Materials and methods: The research was carried out by the method of online questionnaire of employees. A quota sample was used to select respondents. The total volume of online survey is 13,595 people or 1.5% of the staff of Russian Railways. Also interviewed were 1,531 employees of FPK JSC or 2.8% of the staff number of employees. The questionnaire contained a general part, passport part and questions on the main components of a healthy lifestyle, compiled on the basis of the STEPS toolkit. The results of the study: 29% to 71% of respondents adhere to the principles of rational nutrition. The absence of hypodynamy depending on the profession was revealed in no more than half of the respondents. Never smoked from 25% to 65% of workers. An excellent level of commitment to healthy lifestyle was noted in 25%...52% respondents. The largest number of employees who comply with the principles of healthy life is shown among electromechanics, economists, technologists and train crew workers.
STRESS AND MONOTONY AS FACTORS OF LOCOMOTIVE CREWS’ SHIFT WORK
Authors:   FSBSI «Izmerov Research Institute of Occupational Health», Moscow, Russia, Zakrevskaya A.A.
Published: December 2021

Abstract: The article presents the results of a psychophysiological examination of drivers of passenger and export traffic, working in the day and night shifts, respectively. The dynamics of performing psychophysiological tests (changes in the reaction rate, the number of errors, perception of time intervals, etc.) after day and night shifts was revealed, and differences in the subjective perception of the specifics of work in the daytime and at night were also noted. Working the night shift requires the driver to mobilize psychophysiological resources aimed at maintaining active wakefulness and fighting monotony. Day trips are perceived to be more stressful due to more input and traffic. Target: The study of the functional state dynamics of train drivers working without an assistant during day and night trips with an increase in the duration of working hours up to 8 hours in passenger traffic and up to 12 - in export traffic. Methods: 1. Express test of the functional state; 2. «Sense of time» test; 3. Stress resistance test; 4. Survey «Well-being. Activity, mood (SAN)»; 5. Survey «Diagnostics of states of reduced performance (DORS)». Results: The dynamics of the speed and stability of the visual-motor reaction, the accuracy of the perception of time intervals, as well as the subjective perception of the features of day and night shifts by train drivers themselves, makes it possible to distinguish differences in the specifics of shift work: in the daytime it is distinguished by greater intensity, tension, which is reflected in the number of erroneous actions during testing after a day's ride on the simulator, and in the subjective experience of stress noted by the drivers. The need to work at night requires considerable efforts from train drivers to mobilize, which is manifested during a psychophysiological examination before the night shift, however, forced wakefulness during night work leads to a state of monotony among train drivers.
MENTAL PERFORMANCE AND SYSTEMS ANALYSIS
Authors:   FSBSI «Izmerov Research Institute of Occupational Health», Moscow, Russia, Kapustina A.V. , Oniani H.T.
Published: December 2021

Abstract. Introduction. In labor physiology from the position of the theory of functional systems there is a need to assess mental work capacity. The isolation of separate subsystems of labor tension, physiological state allows to develop a complex of measures for the prevention of health disorders. Purpose of the study – scientific substantiation of a systematic approach to the assessment of mental performance based on the study of psychophysiological features of the body of workers under the influence of neuro-emotional loads. Materials and methods. The studies included occupational analysis of work activity, physiological characteristics of CNS and cardiovascular system, and psychological studies with retrospective data analysis (40 professional groups of workers aged 43.80±2.91 years with 17.69±2.19 years of work experience). Statistical processing was performed using IBM SPSS Statistics 20 software and Microsoft Office Excel 2010. Results. At a high degree of labor tension (class 3.3), the formation of an unfavorable physiological state, characterized by an increase in the index of functional changes, high levels of anxiety, an increase in the number of intra- and inter-system correlations in the cardiovascular system and CNS is established according to the materials of production studies Conclusion. System analysis, based on the results of physiological studies, allowed to determine the features of the formation of mental work capacity under different classes of working conditions with the allocation of independent subsystems - neuro-emotional tension of labor processes, physiological state, preventive measures.
HYGIENIC INFLUENCE OF PRODUCTION FACTORS ON THE EPIDEMIOLOGY OF DERMATOSES IN RAILWAY TRANSPORT WORKERS IN THE CONTEXT OF THE COVID-19 PANDEMIC
Authors:   Private Health Agency Departmental «Hospital Clinical «JSC Russian Railways-Medicine» of Barnaul», Barnaul, Russia, Karpova O.A. , Semenikhin V.A. ,   FSBSI HE «Kemerovo State Medical University» of the Ministry of Health of the Russian Federation, Barnaul, Russia, Balandovich B.A. ,   FSBSI HE «Altai State Medical University» of the Ministry of Health of the Russian Federation, Barnaul, Russia
Published: December 2021

Abstract: Introduction. In the context of the COVID-19 pandemic, it is necessary to look for new approaches to the prevention, diagnosis and treatment of skin diseases in the working population. Study objective. To study the hygienic influence of harmful and dangerous factors of the working environment and the severity of the labor process on the structure of the general dermatological morbidity in railway transport workers who ensure the safety of train traffic in the conditions of the COVID-19 pandemic. Materials and methods. The complex of harmful production factors affecting railway transport workers was studied according to the sanitary and hygienic characteristics of the working conditions of employees of the Altai region of the West Siberian Railway of JSC "Russian Railways". The structure of the general dermatological morbidity was studied according to the statistical coupons of outpatient patients who applied to a dermatovenerologist in the CHUZ " CB "Russian Railways-Medicine" Barnaul for the period 2019-2020. Results. The conducted complex of hygienic, epidemiological and statistical studies showed that the combined impact of chemical, meteorological, physical, biological harmful production factors and the severity of the labor process (class 3.1-3.5) in railway transport workers who ensure the safety of train traffic leads to the development of such production-related skin diseases as contact dermatitis and psoriasis. In the context of the COVID-19 pandemic, skin infections (62.8%) predominate over non-infectious dermatoses in the structure of the total dermatological morbidity. The share of primary morbidity increased to 90.8%. The first rank is occupied by pyoderma (47.5%), the second – allergodermatoses (20.0%), the third – mycoses (11.6%). Conclusion. The COVID-19 pandemic leads to changes in the epidemiological and clinical features of dermatoses in the working population, which must be taken into account in their prevention, diagnosis and treatment.
SCREENING CYTOCHEMICAL METHODS IN THE DIAGNOSIS OF PROFESSIONAL AND PROFESSIONALLY CAUSED SKIN PATHOLOGY
Authors:   FBU «FSCH named after F. F. Erisman» of Rospotrebnadzor, Mytishci, Russia, Krasavina E.K. , Yatsyna I.V. , Zhadan I.Y.
Published: December 2021

Abstract: Introduction: Skin diseases of professional etiology remain to this day an urgent problem, despite the low levels of morbidity according to official statistics, due to the high medical and social significance of this pathology. For early diagnosis of occupational and occupational-related skin pathology, it is necessary to investigate laboratory markers that correlate with this pathology. In this regard, a promising direction is to study the activity indicators of hydrolytic enzymes of neutrophils: alkaline and acid phosphatases, the level of myeloperoxidase. Objective: to study and evaluate the effectiveness of cytochemical methods for diagnosing the reactivity of the body in workers exposed to a chemical factor in the workplace. Research methods: hygienic assessment of working conditions of woodworking workers, assessment of the health status and cytochemical parameters of workers. Analysis of the obtained data by methods of mathematical statistics. Results: A hygienic assessment of working conditions and an inspection, with a complex of cytochemical studies, of 148 employees of the chipboard manufacturing enterprise were carried out. The leading factor affecting the body of workers is chemical. A direct strong correlation (r=0.7) was established between the level of dermatological morbidity and the indicators of air pollution of the working area with formaldehyde. Skin pathology was detected in 32.4% of the examined workers. At the same time, the indicators of cytochemical activity in the examined group correlated with the degree of severity of the skin process. Conclusions: Cytochemical indicators in combination with other clinical and diagnostic studies allow us to assess the risk of developing professional and professionally caused skin pathology, which allows us to use them for early diagnosis, and thus contribute to the preservation of labor potential and social adaptation of workers exposed to occupational hazards.
FEATURES OF THE REACTIONS OF THE FUNCTIONAL SYSTEMS OF THE STUDENTS' BODY DURING PERIODS OF HIGH EMOTIONAL STRESS
Authors:   Kazan State Medical University of the Ministry of Health of the Russian Federation, Kazan, Russia, Krasnoshchekova V.N. , Ilyukhin N.Y.
Published: December 2021

Abstract: The study of the features of the reactions of functional shifts of the body systems of students in order to prevent the formation of pathological changes and preserve health at high intensity of the learning process. In the simulated conditions of knowledge control (performance of tests, tasks, practical skills) with the help of the SAN questionnaire, significant fluctuations in activity and mood indicators were revealed (p<0.5), according to the results of the test «Self-assessment of personal stress resistance», 16% of 50 students rated their condition «above average» and changes in hemodynamic indicators-the autonomic Kerdo index and the endurance coefficient indicate a high load on the autonomic nervous system and the inability to perform work productively in the previous mode.
DYNAMICS OF NEUROPHYSIOLOGICAL INDICATORS IN PATIENTS WITH OCCUPATIONAL LUMBOSACRAL RADICULOPATHIES IN THE FOLLOW-UP HISTORY
Authors:   FBRI YMRC for PHPIWof Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Ekaterinburg, Russia, Leyderman E.L. , Shirokov V.A. , Potaturko A.V.
Published: December 2021

Abstract: A prospective study of the features of the course of occupational lumbosacral radiculopathies in the follow-up history was carried out in 88 patients. According to the clinical measures, an inpatient course was found in the 72.5% of cases. According to the results of electroneuromyography (ENMG), 35 (39.8%) patients showed positive dynamics in the form of an increase in the amplitude of the M-response and the conduction velocity of impulse along the motor fibers. In 37 (42.0%) patients, negative dynamics was noted in the form of a decrease in the amplitude of the M-response and the conduction velocity of impulse along the motor fibers. In 16 patients (18.2%) at the time of diagnosis and in the follow-up, the indices of stimulation ENMG were normal.
PROBLEM OF PHYSIOLOGICAL ESTIMATION OF NEGATIVE IMPACT OF FILTERING RESPIRATORY PROTECTION DEVICES TO WORKERS
Authors:   FSBSI «Izmerov Research Institute of Occupational Health», Moscow, Russia, Lemeshko V.I. , Ivanov I.V. ,   Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow, Russia, Geregey A.M.
Published: December 2021

Abstract: Filtering respiratory protection devices are widely used in industry and now in healthcare. The tests that these products undergo assess only the technical characteristics, without considering how the personal protective equipment affects the physiological processes of the user. The purpose of this study was to study modern methods of physiological assessment of the negative impact of the use of filtering respiratory protection devices on the human body. Analyzed domestic and foreign publications. The absence of a unified set of physiological methods for assessing the impact of filtering means of personal respiratory protection on the employee's body was established. This may be due to insufficient actualization of this problem both in Russia and in foreign countries.
DETERMINATION OF INITIAL PARAMETERS LIST FOR PREDICTIVE ASSESSMENT OF OCCUPATIONAL INJURIES
Authors:   NRU «MPEI», Moscow, Russia, Loktionov O.A.
Published: December 2021

Abstract: Introduction. The development and improvement of mechanisms for assessing and predicting occupational injuries, both in the short term and for a long period of time, is a key task in the field of occupational safety for each branch of economic activity. Aim is to determine the list of the most characteristic initial data and parameters for predictive assessment of occupational injuries and accidents of various severity. Research methods. Comparative analysis of various models for assessing and predicting injuries is carried out. Based on the methods of expert analysis, the advantages and disadvantages of each of the methodological approaches are evaluated and the most characteristic initial data for predictive assessment of occupational injuries are highlighted. Results. Necessity of taking into account the complexity of the causes of accidents is established and the most common parameters that are used as initial data for predicting accidents of various severity are determined, which include: profession, employee training, level of training, age, length of service, number of violations.
ON THE ISSUE OF PUBLICATION ACTIVITY IN OCCUPATIONAL HEALTH IN SCIENTIFIC AND EDUCATIONAL INSTITUTIONS OF RUSSIA
Authors:   FSBSI «Izmerov Research Institute of Occupational Health», Moscow, Russia, Lysukhin V.N. , Rubtsova N.B. , Shigan E.E.
Published: December 2021

Abstract: The brief analysis of the application of publication activity indicators of scientific and educational organizations in the field of occupational health based on the first stage of a multi-level study of scientometric data of the RSCI system. The ranking of these organizations by indicators of publication activity was carried out, and the shares of their contribution to the overall indicators of scientific and educational direction were determined. It was found that, despite the predominance of the number of authors and the number of publications, medical universities are significantly inferior to research organizations in terms of the average number of publications per author, i.e. in terms of the scientific performance of employees. The quantitative advantage in publications is due to the versatility of universities, which requires analyzing the topics of the publications themselves. This is the task of the next stages of the study.
ANALYSIS OF EFFECTIVENESS OF THE RISK MANAGEMENT SYSTEM FOR OCCURRENCE OF OCCUPATIONAL DISEASES FOR THE MOST DANGEROUS PROFESSIONS IN BELARUSIAN RAILWAY
Authors:   Belarusian state university of transport, Makeyev V.V. , Rybina T.M. ,   Republican Center for Labor Protection of the Ministry of Labor and Social Protection  of the Republic of Belarus, Bliznets M.V.
Published: December 2021

Abstract. The work examines the most dangerous, according to the results of certification of workplaces, professions of railway transport: driver (assistant) of an electric locomotive and a diesel locomotive, an attendant at a railway station, a track fitter, an electrician of a contact network. An analysis of the legislative acts in force in the Republic of Belarus, as well as local regulatory legal acts created on their basis, OSH management systems based on STB ISO 45001, the results of workplace certification showed the need to create a systematic approach to managing the risks of developing occupational diseases in the most dangerous professions on the railway. The work systematizes the factors that have the greatest influence on the risk of developing occupational diseases, based on the generalization and analysis of certification of workplaces, the leading production factors of the listed professions are highlighted.
ASSESSMENT OF THE ACOUSTIC EXPOSURE ON INDUSTRIAL WORKERS
Authors:   Yekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers of Rospotrebnadzor, Yekaterinburg, Russia, Martin S.V. , Kudryashov I.N. , Ivashchenko M.A.
Published: December 2021

Abstract: Practical experience in the assessment of occupational risk from exposure to excessive noise levels allows us to identify a number of problems. The main ones are the lack of adequate information about the levels of impacting noise and full control of the effects from the health side. The analysis of international experience indicates the need to introduce new approaches to monitoring noise levels into domestic practice, including using individual monitoring devices that minimize the contribution of uncertainties; and identification of the realized effects of its impact, including mandatory audiometry when applying for a job and annual monitoring of the dynamics of hearing changes; evaluation of the effectiveness of the applied PPE in real production conditions.
PROFESSIONAL HEALTH OF ANESTHESIOLOGISTS-REANIMATOLOGISTS
Authors:   Northern (Arctic) Federal University named after M.V.Lomonosov, Arkhangelsk, Russia, Novikova I.A. ,   Northern State Medical University, Arkhangelsk, Russia, Korehova M.V. , Soloviev A.G.
Published: December 2021

Abstract: The work of anesthesiologists-reanimatologists is associated with stressful and extreme working conditions, which increases the likelihood of the development of various occupational health disorders that negatively affect the effectiveness of their activities. In order to identify and describe the characteristics of the professional health of anesthesiologists-reanimatologists, 51 anesthesiologists-reanimatologists of the Arkhangelsk region were examined (average age  51.9 ± 8.7 years). Methods used: questionnaire "Attitude to work and professional burnout" V.А. Vinokura (ORPV), Multilevel personality questionnaire "Adaptability" (MLO-AM) A.G. Maklakov and S.V. Chermyanina, Lusher's color test, “Questionnaire of professional relevance of a personality” by E.V. Kharitonova. It was found that 2/3 of the examined anesthesiologists-reanimatologists have a formed syndrome of professional burnout, characterized by emotional exhaustion, decreased satisfaction with their professional activities and self-esteem, 76.5% - reduced adaptive abilities. 70.6% of doctors have health complaints. Every fifth person is dissatisfied with the degree of realization of their professional potential.
HEALTH MAINTENANCE OF WORKERS EXPOSED TO HAZARDOUS INDUSTRIES AS A POSSIBLE FACTOR IN THE PREVENTION OF OCCUPATIONAL PATHOLOGY
Authors:   Yekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Yekaterinburg, Russia, Obukhova T.Yu. , Budkar L.N. , Gurvich V.B.
Published: December 2021

Abstract: Recent researches in the occupational medicine demonstrate a significant occurrence of cardiovascular and metabolic pathology. They are often associated with occupational activity in workers exposed to hazardous industries. The aim of the paper is to study the condition of somatic health in workers exposed to hazardous industries to identify the trends of preventive measures. Research methods. We studied the influence of somatic diseases in workers of aluminum, refractory and asbestos-processing industries for the development of occupational pathology. Results. The study has identified the relationship of some somatic diseases with work, as well as their influence on the development of occupational pathology: fluorosis, asbestos and silicosis. A predictive mathematical model of the development of arterial hypertension in workers exposed to hazardous industries is created. Conclusion. Therefore, an early diagnosis and prevention of the development of somatic diseases in workers is one of the key areas of current measures to reduce occupational risks.
ACTUAL PROBLEMS OF LASER HYGIENE
Authors:   FSBSI «Izmerov Research Institute of Occupational Health», Moscow, Russia, Paltsev Yu.P. , Pokhodzey L.V.
Published: December 2021

Annotation. The widespread introduction of laser products in various fields of science, technology and medicine, as well as the possibility of serious damage to the organ of vision and skin during their operation, put forward new and increasingly complex tasks for laser hygiene. An analysis of the hygienic normative and methodological documents currently in force on the territory of the Russian Federation showed that they cannot fully ensure laser safety. Differences in the approaches to the hygienic standardization of laser radiation (LR), adopted in the Russian Federation and the USA and the European Union, have been established. The LR hygienic standards in GOST R IEC 60825-1-2013 are practically identical to foreign IEC 60825 standards, that is, in most spectral ranges they exceed the MPL by an order of magnitude or more (SanPiN 1.2.3685-21). The necessity of correcting the hygienic standards of LR, harmonizing the classification of lasers according to the degree of hazard, and developing effective means of control and protection was revealed. Draft documents have been developed: "Hygienic standards for laser radiation" and "Sanitary and epidemiological requirements for working conditions during the operation of laser products", the introduction of which into the practice of sanitary and epidemiological supervision will ensure the preservation of the health of workers. Key words: lasers, correction of hygienic standards, classification, methods and means of control and protection, laser safety.
UPDATING THE HYGIENIC CLASSIFICATION OF WORKING CONDITIONS UNDER THE INFLUENCE OF FACTORS OF THE WORKING ENVIRONMENT AND THE LABOR PROCESS
Authors:   FSBSI «Izmerov Research Institute of Occupational Health», Moscow, Russia, Prokopenko L.V. , Lagutina A.V. , Courierov N.N.
Published: December 2021

Abstract. Introduction. The approval of new sanitary norms and rules within the framework of the “regulatory guillotine” made it necessary to revise the hygienic classification of working conditions in terms of hazard, which includes Guide R 2.2.2006-05 - one of the fundamental documents in medicine of labor. Purpose of the study. Updating the classification of working conditions based on a risk-based approach, taking into account new regulatory legal acts, risk factors due to the introduction of modern technologies and forms of labor organization and practices of applying the classification. Results. The classification of working conditions under the influence of chemical, physical factors, the severity and intensity of the labor process has been revised taking into account SanPiN 1.2.3685-21, the classification of working conditions by biological factor has been revised and supplemented. The characteristics of the classes of working conditions have been clarified, the categories of occupational risk by classes according to R 2.2.1766-2003 are indicated. Changes in the structure of the classification are considered, concerning the abolition of the "optimal" classes of working conditions; expanding the classification in terms of the severity and intensity of labor by adding the classes "harmful working conditions - 3.3"; canceling or bringing the indicators of the "hazardous (extreme) working conditions" class in accordance with Federal Law No. 426-FZ and the principles of hygienic classification. Conclusion. A version of a risk-oriented hygienic classification has been prepared, corresponding to the new regulations, modern conditions and forms of work organization and aimed at preserving and improving the health of workers.
OCCUPATIONAL AND ENVIRONMENTAL ELECTROMAGNETIC SAFETY MAINTENANCE. ISSUES AND PROSPECTS
Authors:   FSBSI «Izmerov Research Institute of Occupational Health», Moscow, Russia, Rubtsova N.B. , Perov S.Y. , Tokarskiy A.Y. ,   SC «RDC FGC UEC», Moscow, Russia
Published: December 2021

Abstract: The brief analysis of different frequency ranges and generation modes electromagnetic field (EMF) occupational and environmental safety problems and prospects improvement criteria and principles are presented. Permissible limit values of ≥3 – 30 and ≥50-300 MHz frequency ranges magnetic field EMF component occupational exposure have been developed based on joint application of domestic and foreign principles of EMF regulation.
ACTUAL QUESTIONS OF DIAGNOSIS AND EXPERTISE OF AN OVERLAPPING BRONCHIAL ASTHMA SYNDROME IN WORKERS OF INDUSTRIAL ENTERPRISES
Authors:   FSBSI «Izmerov Research Institute of Occupational Health», Moscow, Russia, Rumyantseva O.I. , Artemova L.V. , Petrykina M.V.
Published: December 2021

Abstract: Timely diagnosis and treatment of a well-known respiratory pathological state of an overlapping BA syndrome especially due to occupational background remains nowadays an actual clinical problem. In accordance with the reports of public health bodies is often registered among industrial workers in more than 20 occupational in such industries as metallurgy, chemical enterprises, construction, at transport, mechanical engineering, wood processing, animal husbandry, and so on. Along with the leading positions in mortality and occurrence, these pathologies show high levels of comorbidity which complicates differential diagnosis, expertise of work relatedness and treatment. These type of patients should be in a special group because they often show the development of acute processes. The patients often have low life standard. Their respiratory function is often oppressed, their mortality rates are high enough, they go to the doctor’s much more often than patients with other respiratory diseases (1,2,3). Due to these factors, it is necessary to find more informative, clinical and hygienic criteria to develop algorithm of diagnosis and expertise for this group of occupational patients.
DYNAMICS AND FEATURES OF THE FORMATION OF REGIONAL PROFESSIONAL INCIDENCE
Authors:   FSBEI HE Kazan State Medical University of the Ministry of Health of Russia, Kazan, Russia, Sabitova M.M. , Berkheeva Z.M. , Shulaev A.V.
Published: December 2021

Abstract. Working conditions have a significant impact on the health of the working population. In the Republic of Tatarstan (RT), there are still industries where unsatisfactory working conditions lead to a high risk of developing occupational diseases. The aim of the work was to assess the occupational morbidity (DI) in the Republic of Tatarstan of the structure, dynamics, main reasons and factors affecting its formation. The aim of the work was to assess the occupational morbidity (DI) in the Republic of Tatarstan of the structure, dynamics, main reasons and factors affecting its formation. The analysis was carried out on the basis of data from the Office of Rospotrebnadzor in the Republic of Tatarstan, the Center for Occupational Pathology, and Tatarstanstat. Results: The proportion of workers employed in harmful and (or) hazardous working conditions in the Republic of Tatarstan amounted to 47.9% -50.8% of the payroll number of the working population. PP indicators in the Republic of Tatarstan over the past 10 years are 1.39 - 1.88 per 10 thousand employees. The highest levels of PZ are recorded among agricultural workers - from 5.22 to 10.12 and manufacturing - from 3.46 to 7.41 cases per 10 thousand. The leading places are occupied by diseases associated with exposure to noise and vibration. The main share of the identified occupational diseases was registered in workers of working age (50-59 years) with over 30 years of work experience. Conclusion. During the analyzed period, the PP indicators in the Republic of Tajikistan remained higher or at the level of the PP in the Russian Federation (RF). The main share of occupational diseases was registered at aircraft and mechanical engineering enterprises. We associate the observed increase in the proportion of diseases with the loss of professional ability to work with the untimely referral of patients for examination, as well as their late appeal to the center of occupational pathology.
FORMATION OF OCCUPATIONAL AND NON-OCCUPATIONAL DISEASES IN UNDERGROUND APATITE ORE MINERS
Authors:   Northwest Public Health Research Center, S-Petersburg, Russia, Syurin S.A. , Kovshov A.A.
Published: December 2021

Abstract. Introduction. Living and working in the Arctic is associated with an increased health risks. The aim of the study was to assess features of non-occupational and occupational disease formation in underground apatite ore miners in the Kola Arctic. Materials and methods. We studied data ofthe periodic medical examination and results of social and hygienic monitoring "Working conditions and occupational morbidity of the population of the Murmansk region". Results. In 2007, 2649 miners were diagnosed with 6778 chronic diseases, of which the most prevalent were diseases of the musculoskeletal system (34.4%) and eye (16.9%). In 2008-2019, 496 occupational diseases were diagnosed for the first time in 290 (10.9%) miners. The risk of developing occupational pathology in drifters exceeded indicators of all other miners, including lumbermen (RR = 1.60; CI 1.07-2.38, р=0,015), operators of a vibratory loading installation (RR = 1.63; CI 0.97-2.74, p=0,041), drillers (RR = 1.57; CI 1.11-2.22, р=0,009) and blasters (RR = 2.13; CI 1.56-2.90, р<0,001). In the structure of occupational diseases, the first places were occupied by vibration disease (19.7%), radiculopathy (19.3%) and deforming osteoarthritis (16.0%). Conclusion. Modernization of ore mining processes and personal protective equipment, as well as a current system of medical measures should include more effective solutions to the problems of preserving health of underground apatite miners in the Kola Polar region.