bluuebunny/crossref_metadata_2025 huggingface dataset:
Last interglacial sea-level proxies in the Korean Peninsula
Authors: Ryang Woo Hun , Simms Alexander R. , Yoon Hyun Ho , Chun Seung Soo , Kong Gee Soo
Published: July 2021

Abstract. Like most of the world’s coastlines, the Korean Peninsula experienced higher-than-present sea levels during the Last Interglacial (LIG) otherwise known as Marine Isotope Stage (MIS) 5e. However, the expression of that highstand in sea levels differs across the eastern and western Korean Peninsula. The active east coast of the Korean Peninsula is characterized by broad uplifted marine terraces, while the stable west coast is characterized by tidal flats and rias. In this study, we used a standardized database template to review and extract the existing constraints on LIG sea levels along both the east and west coasts of the Korean Peninsula. A total of 62 LIG constraining data points were compiled including 34 sea-level indicators, 22 marine limiting records, and 6 terrestrial limiting records. The ages from these data points are based on 61 optically stimulated luminescence (OSL) measurements and 1 paleomagnetic-based age. Along the uplifted east coast, LIG sea-level indicators based on marine terraces are at elevations ranging from +9 to +32 m. The uplifted marine terraces are cut or otherwise deformed by faults developed under a compressional regime due to backarc closing of the East Sea since the early Pliocene. As a result, tectonic uplift likely contaminates the elevation of the east coast LIG shorelines. On the contrary, LIG sea-level constraints on the west coast of the Korean Peninsula are found at heights of between +2 and +5 m and include marine and terrestrial limiting records as well as true sea-level indicators. The LIG sea-level constraints along the west coast of the Korean Peninsula are likely uncontaminated by vertical movement or experienced minor subsidence during the Quaternary.
Evaluating an exponential respiration model to alternative models for soil respiration components in a Canadian wildfire chronosequence (FireResp, v1.0)
Authors: Zobitz John , Aaltonen Heidi , Zhou Xuan , Beninger Frank , Pumpanen Jukka , Köster Kajar
Published: July 2021

Abstract. Forest fires modify soil organic carbon and suppress soil respiration for many decades since the initial disturbance. The associated changes in soil autotrophic and heterotrophic respiration from the time of the forest fire however, is less well characterized. We analyzed models of soil autotrophic and heterotrophic respiration with a novel dataset across a fire chronosequence in the Yukon and Northwest Territories of Canada. The dataset consisted of soil incubation experiments and field measurements of soil respiration and soil carbon stocks. The models ranged from a Q10 (exponential) model of respiration to models of heterotrophic respiration using Michaelis-Menten kinetics parameterized with soil microbe carbon. For model evaluation we applied model selection metrics (Akaike Information Criterion) and compared predicted patterns in soil respiration components across the chronosequence. Parameters estimated with data from the 5 cm soil depth had better model-data comparisons than parameters estimated with data from the 10 cm soil depth. The model-data fit was improved by including parameters estimated from soil incubation experiments. Models that incorporated microbial carbon with Michaelis-Menten kinetics reproduced patterns in autotrophic and heterotrophic soil respiration components across the chronosequence. Autotrophic respiration was associated with aboveground tree biomass at more recently burned sites, but this association was less robust at older sites in the chronosequence. Our results provide support for more structured soil respiration models than standard Q10 exponential models.
A HIGH-CURRENCY GEO-SPATIAL SERVICE GATEWAY FOR NATIONAL GEO-INFORMATION SERVICE PLATFORM
Authors: Zhang H. , Huang W. , Jiang J. , Du M. , Yang J.
Published: July 2021

Abstract. Today, more and more geospatial services are provided by the governments and enterprises to share various geographic information data and functions, and services-based application integration has become a trend. However, many problems existed in the geo-platform for Geographic information sharing while providing services in the form of API, such as the coexistence of different versions of the same service, similar service routes of different APIs, cluttered service protocols, and complex authority management, that makes the integration among different geographic information services difficult and reduces the development efficiency. There are already some API gateway technologies to solve the problem, but the characteristics of geospatial services are not considered in the existing product. To address these problems, this paper proposed a high-currency geospatial service gateway system for National Geo-Information Service Platform based on the opensource framework of Kong for realizing the unified management and authorized open. The system provides the whole lifecycle management and fine-grained control for the service, and the functions such as unified geospatial service access, protocol conversion, service management, authorization verification, rate limiting, and security protection are also equipped. The system has been released and integrated in the National Geo-Information Service Platform, supporting hundreds of millions of service invocation every day. The result proves it simplifies geospatial services management, deployment, and application, and benefits the exchanging and sharing of geographic information.
PUBLIC-PRIVATE COOPERATION MODELS FOR EFFICIENT ACCESS TO GEOSPATIAL CONTENT
Authors: Musäus S. W.
Published: July 2021

Abstract. Traditional public data procurement models for geospatial data sets as basemaps are not any longer alone the spatial reference for decision processes. A fast digitalizing society requires more flexibility and speed in the information streams. Public authorities have to deal with reducing budgets and higher demand, while the industry is searching for new business models. A smart and flexible design of public-private cooperation models increases the value for all stakeholders through (a) negotiated quality levels, (b) reduced unit prices, (c) stable income to all suppliers, (d) risk reduction to the authorities. The models allow for a high flexibility on product definition and orient themselves on the demands of the public and private markets alike.
Anomalous Amide Proton Chemical Shifts as Signatures of Hydrogen Bonding to Aromatic Sidechains
Authors: Baskaran Kumaran , Wilburn Colin W. , Wedell Jonathan R. , Koharudin Leonardus M. I. , Ulrich Eldon L. , Schuyler Adam D. , Eghbalnia Hamid R. , Gronenborn Angela M. , Hoch Jeffrey C.
Published: July 2021

Abstract. Hydrogen bonding between an amide group and the p-π cloud of an aromatic ring was first identified in a protein in the 1980s. Subsequent surveys of high-resolution X-ray crystal structures found multiple instances, but their preponderance was determined to be infrequent. Hydrogen atoms participating in a hydrogen bond to the p-π cloud of an aromatic ring are expected to experience an upfield chemical shift arising from a shielding ring current shift. We survey the Biological Magnetic Resonance Data Bank for amide hydrogens exhibiting unusual shifts as well as corroborating nuclear Overhauser effects between the amide protons and ring protons. We find evidence that Trp residues are more likely to be involved in p-π hydrogen bonds than other aromatic amino acids, whereas His residues are more likely to be involved in hydrogen bonds with a ring nitrogen acting as the hydrogen acceptor. The p-π hydrogen bonds may be more abundant than previously believed. The inclusion in NMR structure refinement protocols of shift effects in amide protons from aromatic side chains, or explicit hydrogen bond restraints between amides and aromatic rings, could improve the local accuracy of side-chain orientations in solution NMR protein structures, but their impact on global accuracy is likely be limited.
Adaptation and Application of the large LAERTES-EU RCM Ensemble for Modeling Hydrological Extremes: A pilot study for the Rhine basin
Authors: Ehmele Florian , Kautz Lisa-Ann , Feldmann Hendrik , He Yi , Kadlec Martin , Kelemen Fanni Dora , Lentink Hilke Simone , Ludwig Patrick , Manful Desmond , Pinto Joaquim Ginete
Published: July 2021

Abstract. Enduring and extensive heavy precipitation associated with widespread river floods are among the main natural hazards affecting Central Europe. Since such events are characterized by long return periods, it is difficult to adequately quantify their frequency and intensity solely based on the available observations of precipitation. Furthermore, long-term observations are rare, not homogeneous in space and time, and thus not suitable to run hydrological models (HMs) with respect to extremes. To overcome this issue, we make use of the recently introduced LAERTES-EU (LArge Ensemble of Regional climaTe modEl Simulations for EUrope) data set, which is an ensemble of regional climate model simulations providing over 12.000 simulated years. LAERTES-EU is adapted for the use in an HM to calculate discharges for large river basins by applying a quantile mapping with a fixed density function to correct the mainly positive bias in model precipitation. The Rhine basin serves as a pilot area for calibration and validation. The results show clear improvements in the representation of both precipitation (e.g., annual cycle and intensity distributions) and simulated discharges by the HM after the bias correction. Furthermore, the large size of LAERTES-EU improves the statistical representativeness also for high return values above 100 years of discharges. We conclude that the bias-corrected LAERTES-EU data set is generally suitable for hydrological applications and posterior risk analyses. The results of this pilot study will soon be applied to several large river basins in Central Europe.
Sistem Informasi Pengelolaan Data Panti Sosial Jompo Dhuafa Sayang Ummi Berbasis Website Di Kota
Authors: Elvionita Delvi , Sari Febrina
Published: July 2021

Yayasan Panti Jompo Dhuafa Sayang Ummi Dumai merupakan salah satu rumah lansia yang telah memakai sistem informasi berupa pemakaian perangkat komputer dalam menjalankan aktifitas kerjanya, akan tetapi dalam penggunaannya belum secara menyeluruh karena hanya pengolahan data para lansia saja yang menggunakan perangkat komputer dengan menggunakan aplikasi perkantoran yaitu Microsoft Office. Sehingga masih banyak data seperti data instruktur, data kegiatan, data donator, dan data donasi masih dilakukan secara manual dengan dicatat di dalam buku besar. Selain itu tidak optimalnya penyebaran informasi tentang panti jompo karena informasi disampaikan hanya dari mulut ke mulut sehingga masyarakat atau donatur yang ingin mengetahui informasi tentang  panti harus datang lansung ke panti atau menggunakan via telepon. Berdasarkan permasalahan tersebut, maka diperlukan suatu website yang dapat mempermudah para admin yang bekerja di Yayasan Panti Jompo Dhuafa Sayang Ummi di Dumai dalam memberikan informasi terkini seputar panti. Maka penulis merancang sebuah website dengan judul Sistem Informasi Pengelolaan Panti Sosial Jompo (Lansia) Dhuafa Sayang Ummi berbasis Website Di Kota Dumai.
Implementasi Metode Reverse Osmosis Pada Perhitungan Kapasitas Tangki Pengolahan Air Laut
Authors: Nuryasin Abdillah
Published: July 2021

Air terbagi beberapa jenis seperti asin dan air tawar. Air asin terdapat di laut karena memiliki memiliki rasa asin berlebih. Pada musim kemarau panjang masyarakat kesulitan mendapatkan air bersih. Masyarakat memerlukan tangki penyedia air untuk menampung dan mengolah air bersih dengan menggunakan membran. Membran pengolah air umumnya berbasiskan polimer. Tangki penyedia air dihitung kapasitasnya baik dari bahan plat stainless steel, viber dan beton untuk menentukan ukuran dengan menghitung menggunakan kecepatan aliran baik itu bentuk tabung maupun berbentuk balok. Dalam pelaksanaan penelitian ini pada saat teknik pengolahan didapatkan dari data sekunder oleh pihak perusahaan agar pengolahan air dari zat terlarut yang tinggi menjadi rendah sedangkan perhitungan kapasitas tangki dihitung dengan metode Mc. Cabe and Smith dan dibandingkan dengan data primer perusahaan agar metode perhitungan ini dapat dipakai pada saat merancang tangki untuk pengolahan air laut dengan menggunakan mesin reverse osmosis
La construcción de la identidad a través del arte en personas en riesgo de exclusión social
Authors: Cara Cristina Berruezo , Morón Velasco Mar
Published: July 2021

Este artículo recoge la investigación que pretende estudiar el impacto del arte en la construcción de la identidad de los individuos y, concretamente, de aquellos que se ubican en colectivos en riesgo de exclusión social. Para alcanzar este objetivo se sigue una investigación etnográfica mediante la entrevista semiestructurada en profundidad a artistas que pertenecen a diferentes colectivos en riesgo de exclusión social.

Después de realizar esta investigación, se han podido comprobar los beneficios que realmente aporta el arte y la educación artística. Beneficios que, además, se ven acentuados en el caso de las personas que forman parte de algún colectivo en riesgo de exclusión social, ya que el arte les supone un medio de expresión, de autoconocimiento, autodeterminación y empoderamiento, un mecanismo de reivindicación y, en definitiva, un arma política y social. Además, se ha visto como la relación con el arte les otorga reconocimiento y amplía los vínculos socio-afectivos a través de la flexibilidad y la comprensión de diferentes puntos de vista y la asociación en diferentes grupos de pertenencia. También permite que personas vulnerables a la exclusión social acaben formando parte de la sociedad que le reconoce su talento y valora su obra por encima de sus características personales. Por lo tanto, se hace patente la importancia de que la educación artística forme parte del currículo de Educación Primaria como herramienta que favorece la inclusión educativa y social.
Misgendering as epistemic injustice: A queer STS approach
Authors: Argyriou Konstantinos
Published: July 2021

Misgendering is perceived as the use of incorrect pronouns and gender categories when addressing Transgender and Gender Non-Conforming (TGNC) people. This common habit is widely observed in reports, surveys and assessments, where the pressures to comply with a binary understanding of gender are high and alternative options for self-identification are not frequently offered. The present study reads misgendering as a manifestation of epistemic injustice, and uses resources from Science, Technology and Society (STS) Studies in order to highlight the importance of situated perspectives on the matter. After being analysed as a commonplace microaggression, misgendering is conceptualised as an act of structural hermeneutical marginalisation that is not usually intentional but product of society’s lack of sensibility towards gender diversity. Finally, a reparative approach against misgendering is offered through the Gender Fair Language model, which involves relational and situated contributions in order to prevent already marginalised people and experiences from being further excluded.
César Ruiz Sanjuán, Historia y sistema en Marx. Hacia una teoría crítica del capitalismo, Madrid, Siglo XXI, 2019, 400 pp.
Authors: Calcerrada Fernández Jaime
Published: July 2021

Historia y sistema en Marx
Caminos y derivas para otra investigación educativa y social
Authors: Pérez Ferra Miguel
Published: July 2021

El archivo se corresponde con la reseña del libro indicado en el trabajo. Se corresponde a un análisis de la realidad investigadora en el ámbito de la educación, en particlar, y de las ciecnias sociales, en general. Y a propuestas diferentes analizadas desde las perspectivas ontoepistemológicas, metodológicas y éticas.
Standard setting organizations and open source communities: Partners or competitors?
Authors: Boehm Mirko , Eisape Davis
Published: July 2021

Standardization serves a as a means to improve overall quality of life through the economies of scale gained from the pervasive adoption of technical solutions. It enables competition by facilitating interoperability between products of different vendors. The wider open source community develops free and open source software (FOSS) in a global upstream/downstream model that similarly benefits society as a public good. FOSS and standards setting organizations (SSOs) are both instruments causing standardizing effects. Innovators and policy-makers assume that a mutually beneficial collaboration between them is desirable. However, their exact relationship is not fully understood, especially when and how FOSS and SSOs complement each other, or displace each other as competitors. To be able to compare FOSS and SSOs, our study develops a phase model of standardization that is applicable to both approaches, and applies this model to compare the strengths and weaknesses of FOSS and SSOs against common opportunities and threats in the ICT sector. Based on qualitative expert interviews with FOSS and SSO representatives, the synthesis of the separate results support conclusions from a product, a process and a societal perspective. The study identifies cost of change as a key determinant for the efficacy of each approach. It concludes that FOSS and SSOs create complementary products, compete for efficiency of the standardization process, and are both independent and complementary standardization instruments available to industry and influenceable by policy-makers. The paper closes with a discussion of possible implications relevant to businesses, the wider open source community, SSOs and policy-makers.
The US-Taliban Agreement
Authors: Mohmand Abdul Qayum
Published: July 2021

The current peace agreement is not a receipe for peace in Afghanistan, but it is a start. The Afghan government was excluded from the initial peace negotiations in Qatar, but the outcome provides some leverage not only to the  United States, and the Taliban, but also the Afghan Government.  The term intra-Afghan is not defined in the agreement, therefore, both the Afghan Government and the Taliban can use it to their advantage.
Організаційно-правові механізми державного управління озелененням міст України
Authors: Л.О. Погребняк
Published: July 2021

Визначені недоліки організаційно-правового регулювання державної політики
України у сфері озеленення населених пунктів та їх причини, обов’язки державних органів влади та органів місцевого самоврядування з утримання та догляду за
об’єктами озеленення та надані рекомендації щодо шляхів удосконалення організаційно-правових механізмів державного управління озелененням міст.
Стратегічне планування розвитку регіонів як організаційний механізм публічного управління
Authors: В.М. Проданик , А.М. Шинкарьов
Published: July 2021

Наразі в Україні відбувається процес формування нової державної регіональної
політики, зокрема на засадах використання саме механізмів публічного управління та
законодавчого її забезпечення. Метою такого формування є створення умов для поліпшення якості життя людини, додержання гарантованих державою соціальних
стандартів для кожного громадянина незалежно від його місця проживання, через
забезпечення територіально цілісного та збалансованого розвитку України, інтеграції регіонів в єдиний економічний, політичний, правовий, інформаційний та культурний простір, максимально повного використання їх потенціалу з урахуванням природних, політичних, історичних, культурних, соціальних і інших особливостей, підвищення конкурентоспроможності регіонів і реалізації дієвого самоуправління.
У статті обґрунтовано, що ефективний розвиток неможливо здійснити без
реальної децентралізації, зміцнення самоврядування в Україні та залучення територіальних громад до формування, впровадження політики (стратегічного бачення) регіонального розвитку.
Державна стратегія регіонального розвитку на 2021-2027 роки, яка затверджена постановою Кабінету Міністрів України від 5 серпня 2020 р. № 695 є основним планувальним документом для реалізації секторальних стратегій розвитку, координації державної політики в різних сферах, досягнення ефективності використання державних ресурсів у територіальних громадах і регіонах в інтересах людини, єдності держави, сталого розвитку історичних населених місць та збереження
традиційного характеру історичного середовища, збереження навколишнього природного середовища та сталого використання природних ресурсів для нинішнього та
майбутніх поколінь українців.
Доведено, що найбільш суттєвими викликами, на які держава має реагувати
шляхом вироблення та реалізації державної регіональної політики, є неспроможність більшості територіальних громад самостійно вирішувати питання, віднесені до їх повноважень. В цілому, передавати повноваження та відповідальність за
регіональний розвиток на органи місцевого самоврядування не можна допоки не буде
створена дієва і ефективна система місцевого самоврядування і, у першу чергу,
дійсно спроможна та економічно стійка територіальна громада.
Traffic conflict
Authors: O Stepanov , T Yarmak , A Venger
Published: July 2021

The article is devoted to the conceptual consideration of the formation and development of the theory of transport conflicts in the transport process. The early studies of
transport conflicts by foreign scientists are shown. The authors come to the conclusion that traffic conflicts depend on the psychophysiology of road users, which must be taken into account in the psychology of traffic conflicts.
Державна стратегія продовольчої безпеки України
Authors: Ю.Г. Батир
Published: July 2021

У статті охарактеризовано основні підходи до оцінки продовольчої безпеки
країни. Наведено стан продовольчої безпеки країн світу із застосуванням Глобального індексу продовольчої безпеки. Встановлено, що за рядом показників рівень продовольчої безпеки України є достатнім, але за окремими показниками в розрізі певних
груп продуктів харчування, він є загрозливим. Основними чинниками, що мають визначальний вплив на рівень харчування населення є доходи населення та цінова політика, а пропозицію формує рівень ефективності діяльності сільського господарства
та харчової промисловості. Продовольча незалежність за окремим продуктом вказує на те, що задоволення потреб населення у продовольстві, у межах його купівельної спроможності переважно забезпечується за рахунок продукції вітчизняного виробництва. Встановлено, що в країні стало розвивається тільки один сектор АПК –
рослинництво, але тваринництво та всі інші суміжні галузі стагнують. Визначено
пріоритетні напрями реалізації стратегії національної безпеки України.
Women entrepreneurship in the MENA region: Factors influencing entrepreneurial motivation
Authors: Touissate Hind , AZDIMOUSA Hassan
Published: July 2021

Women's entrepreneurship has been relevant for several years in the MENA region. It has been recognized as a lever for economic and social growth as well as a tool for job creation attracting more and more theorists and researchers from across the globe. In this particularly buoyant context, the goal of our research paper is to identify the factors influencing the motivation of women entrepreneurs in this region on the assumption that socio-cultural and individual factors are at the heart of women's entrepreneurship in the MENA region. The answers are supported through a qualitative study based on the empirical results of a survey of 45 innovative entrepreneurs from 10 different countries between 2017 and 2020 and based on an in-depth literature review.
L'entrepreneuriat innovant et le développement du secteur audiovisuel au Maroc. Cas de la Société Nationale de Radiodiffusion et de Télévision
Authors: BELBACHIR Mohammed , ZAMMAR Rachid
Published: July 2021

Depuis l’émergence de la pandémie Covid 19, plusieurs secteurs dans le monde ont été véritablement impactés. Ainsi, le secteur audiovisuel au Maroc a beaucoup souffert de cette conjoncture. Le recours à l'entrepreneuriat innovant devient une nécessité incontournable. Pour cette raison, le gouvernement marocain a instauré une panoplie de mesures d’ordre financier, juridique et administratif afin de relancer ce secteur. Dans cette optique, nous ambitionnons à travers cet article de mettre en relief l’interaction entre l’entrepreneuriat innovant et le secteur audiovisuel au Maroc.

Ainsi, ce papier vise à décortiquer à quelle ampleur l’entrepreneuriat innovant peut impacter le secteur audiovisuel ainsi que les multiples programmes établis afin de promouvoir ce secteur. Afin de bien formuler une vision plus claire et exhaustive, notre étude a été focalisée sur la société Nationale de Radiodiffusion et de Télévision (SNRT) étant la locomotive de ce secteur au Maroc. Pour ce faire, une étude documentaire a été également réalisée par le biais des développements scientifiques et des analyses de monographies, des rapports et des graphiques portant sur ce domaine surtout de cette société. Cette analyse documentaire nous a permis de confirmer l’importance de l’entrepreneuriat étant un facteur névralgique de la relance de la dynamique de ce secteur à court terme. Cependant, vu le coût élevé généré par l’introduction de nouveaux procédés et technologies, l’impact de l’innovation se sera concrétisé qu’après une période bien déterminée.
The school and the military: two precursors of physical education and sport in northern Morocco during the protectorate
Authors: HARFOUF SOULAIMAN
Published: July 2021

Considered rather as a protectorate, the Spanish colonization of northern Morocco allowed the establishment of a new culture among the natives: the sports culture. The socio-political context of the emergence and the social and geographical dissemination of sports activities and physical education (PE) in schools explain why they were put at the service of the patriotic and militaristic national colonial conception.

This conception was implemented by two ideological apparatuses: the school and the army. The action of these two agents in charge of disseminating sport and PE among the Moroccan population aimed at highlighting the possibility that colonial Spain would have to prepare future men-soldiers capable of responding to the aspirations of the conquering state. Sport was instrumentalized and became an effective channel of political communication.
Application of theory of planned behavior to study online booking behavior
Authors: Christina Yuli , Yasa Ni Nyoman Kerti
Published: July 2021

The development of the internet has influenced the development of the world economy. Various buying and selling transactions that previously could only be done face-to-face, have now developed into transactions via the internet known as e-business or e-commerce. The hotel room online booking system was created to make it easier for consumers to book rooms 24 hours a day. With the availability of the online booking feature, consumers can access hotel information in detail and more transparently, besides that, consumers can also see reviews which can be used as their consideration in choosing hotels and planning holidays. Traveloka's significant development as an Indonesian online travel agent unicorn plays an important role in accelerating the growth rate of the online travel ecosystem, especially for the domestic market. There are many factors that must be examined in finding information, placing orders, and purchasing online. Therefore, this research is focused on online booking behavior. This study aims to determine the influence between variables based on Theory of Planned Behavior, which consists of attitude toward the online booking behavior, subjective norm, perceived behavioral control, online booking intention and online booking behavior at Traveloka. Data was collected from 133 respondents of domestic tourists who have made online bookings at Traveloka. Data were analyzed using Partial Least Square (PLS) statistics with the Smart PLS 3.0 M3 program to determine the complexity of the relationship between latent variables and their indicators. The results of this study indicate that attitude toward the behavior and subjective norms have a positive and significant effect on online booking intention. Meanwhile, perceived behavioral control has no significant effect on online booking intention. Another finding is that online booking intention and perceived behavioral control are known to have a positive and significant effect on online booking behavior. Traveloka management and marketers are also expected to be able to use the results of this research to evaluate and take corrective action on aspects that are deemed inadequate and manage the ease of use of the application to increase online booking intentions through the Traveloka application.
Empirical study of Indonesian SMEs sales performance in digital era: The role of quality service and digital marketing
Authors: Djakasaputra Arifin , Wijaya Oscarius Yudhi Ari , Utama Andrew Shandy , Yohana Corry , Romadhoni Buyung , Fahlevi Mochammad
Published: July 2021

This research aims to analyze the relationship between digital marketing on quality service, digital marketing on sales performance, quality service on sales performance, and digital marketing on Sales performance through quality service. The research methodology is a quantitative method and divided into research design and research subjects, data collection methods, and analysis methods. The study is conducted on 125 small and medium (SMEs) in Banten, Indonesia in the digital region. The study uses primary data based on the results of distributing online questionnaires to 125 managers of SMEs in Banten who were selected by simple random sampling. The questionnaire was designed online, and each question/statement item was given five answer options, namely: strongly agree (SS) score 5, agree (S) score 4, neutral / doubt (N) score 3, disagree (TS) score 2, and strongly disagree (STS) score 1. The method for processing data is by using PLS and using SmartPLS version 3.0 software. Based on data analysis by SmartPLS, digital marketing has a significant effect on quality service, digital marketing has a significant effect on sales performance, quality service has a significant effect on sales performance, and digital marketing significantly affects sales performance through quality service in the digital era.
The effects of knowledge sharing, social capital and innovation on marketing performance
Authors: Setini Made , Yasa Ni Nyoman Kerti , Supartha I Wayan Gede , Giantari I Gusti Ayu Ketut
Published: July 2021

Women entrepreneurs and the informal sector are looking for footholds in the COVID-19 pandemic, which will lead women to develop creative businesses. This study examines the role of sharing knowledge and innovation in addressing gaps in social capital and marketing performance. Purposive sampling is used in the technique sample with 229 samples and Structural Equation Modeling (SEM-PLS) analysis techniques with SmartPLS is used for processing applications. The results show that social capital has a positive effect on the business performance of women entrepreneurs in Bali, Indonesia. The knowledge-sharing variable can be a mediator in the relationship between social capital and performance, and social capital has a significant positive effect on innovation, but innovation does not have a positive effect on marketing performance and knowledge sharing. In the end, women entrepreneurs will use knowledge sharing to create various innovations to meet market demand. However, opportunities for women entrepreneurs are very limited on capital due to the lack of guaranteed capital, and a lack of entrepreneurial skills in the era of technology, market access, bureaucracy, and legal matters. In addition, managerial skills, access to information technology, and the perspective that men should excel in Balinese culture and customs, limit business for women entrepreneurs.
Exploring the determinants of Internet continuance intention and the negative impact of Internet addiction on students’ academic performance
Authors: Maqableh Mahmoud , Obeidat Ahmad , Obeidat Zaid
Published: July 2021

This study aims to investigate the impact of integrating essential factors on Internet usage continuance intention in students’ context. The proposed model examines the influence of perceived enjoyment, perceived image, satisfaction, information value, and emotional value on Internet continuance intention. Additionally, it investigates the role of Internet addiction, satisfaction, and continuance intention on academic performance among university students. A survey questionnaire method was adopted to collect data from university students in Jordan. Data was collected from 450 voluntary participants, and the analysis was conducted using SPSS and AMOS. The analysis results show that perceived enjoyment, perceived image, information value, and emotional value have a significant positive influence on continuance intention of Internet use. Besides, the results show that continuance intention has a positive impact on satisfaction and Internet addiction. While continuance intention has a significant positive impact on students’ academic performance, and Internet addiction has a significant negative impact on students’ academic performance, the impact of satisfaction on academic performance was not supported. This study is the first to examine integrating of perceived enjoyment, perceived image, information value, and emotional value on Internet continuance usage. Furthermore, this study is also distinguished from other studies by investigating the negative impact of Internet addiction on students’ academic performance gap.
Maternal and Child Health in Northern Cyprus
Authors: SARPKAYA GÜDER Dilek
Published: July 2021

The data insufficiency in maternal and child health criteria may lead to deficiencies in the planning of primary healthcare services. The review aimed to provide information on the general health status of Northern Cyprus with scientific studies conducted in the country along with maternal and child health indicators presented at national level. This review research uses description and documentary analysis methods. In this study, the data was collected from publications using data collection techniques. Many health indicators have been defined by the world health organization (WHO) and Turkey to evaluate maternal and child health. The data in this study was presented accordingly. It has been stated that in Northern Cyprus, the infant mortality rate is 0.8 per thousand live births, the crude birth rate is 14.6 per thousand, and the fertility rate is 1.8. No stillbirth has been reported between 2013-2017. In the studies performed, it has been found that the cesarean delivery rate was high (47.6%-87.0%) and that the rate of exclusive breastfeeding in the first 6 months was very low (22.4-41.7%). There are no sufficient data on maternal and child health indicators in the country. No primary data such as maternal mortality rate, infant mortality rate, mortality and stunting rate under five years of age, immunization in children, adolescent pregnancy rate, and frequency and scope of prenatal and postnatal care was available.
Formulation and Evaluation of Mouth Dissolving Tablet of Benazepril Hydrochloride
Authors: Bhargava Vani H. , Sable Poonam S. , Kulkarni Deepak A. , Darekar Geeta P.
Published: July 2021

Antihypertensive drugs are expected to give quicker action with better bioavailability. In the present study, mouth dissolving tablets of Benazepril Hydrochloride were formulated by using direct compression technique employing combination of a superdisintegrants to achieve rapid disintegration of the tablets in oral cavity Croscarmellose sodium, sodium starch glycolate and crospovidone were used as superdisintegrant to prepare six batches of mouth dissolving tablets out of which tablets prepared from crospovidone showed best results. Drug and physical mixture was characterized by FTIR for compatibility study. Optimization technique was employed to predict the best formulation of all the combinations prepared. Prepared formulations were optimized and evaluated for wetting time, dispersion time and different quality parameters. Optimized formulation was compared with marketed formulation for in vitro drug release and it was found that mouth dissolving tablet shows efficient drug release.
Comparative Evaluation of Microleakage of Two Step Etch and Rinse, Two Step Self Etch and Universal Dentin Bonding
Authors: Mohammad Reza Soltani , Dadfar Nasim , Ghannadan Kiana
Published: July 2021

Introduction: Dental composites have been extended as the selected material in most of recent restorations. However, the contraction caused by their polymerization remains the main issue. The stress made by this contraction could cause the divide of composite-tooth junction to be severed. Bacteria, liquids, molecules or ions could cross the gap made between the repair and the cavity wall which this process is called micro-leakage. Micro-leakage causes leakage, tenderness, secondary decay, damage to the pulp, marginal discoloration, which finally results in restoration failure. It can be said that the success of resin restoration material depends perfectly on the ability of the enamel and dentin bonds. This research aims to determine the best bonding to decline micro-leakage. Materials and Methods: In this research, 48 human premolar teeth were prepared without decay, restoration, fracture and wear. Each class V standard cavity was prepared on buccal and lingual surfaces. The shaved teeth were randomly divided into 4 groups including 12 ones. They were polished after restoration. All samples of the 4 groups were subjected to the heat cycling. Apex was sealed with adhesive wax and all parts of the tooth were covered with two layers of nail polish. The samples were incubated in 0.5% Fuchsin solution for 24 hours at room temperature. After that, they were washed under the faucet and the nail polish was removed from tooth surface. Teeth were divided into two mesio distal sections by a cutting machine. Samples were observed by stereo microscope. samples were evaluated based on the micro-leakage grading. Kruskal-Wallis, Mann-Whitney and Will Coxson tests were used to evaluate the results. Results: In each group, 48 cavities were examined. The results of this research showed that in none of enamel surface of bindings, micro-leakage was observed. In the dentine area, the least amount of micro-leakage was related to the Clearfil SE Bond. There was no statistically significant difference between the micro-leakage of Clearfil SE Bond and G Premio Bond by Self Etch method (P value> 0.05). Also, there was no significant difference between micro-leakage of G_Premio Bond by Self Etch and G_Premio Bond by Etch and Rinse method. The micro-leakage of Adper Single Bond 2 was significantly higher in the dentin rather than the other groups. Conclusions: In dentine level, the highest micro-leakage was related to Adper Single Bond 2 bonding and the least one was in Clearfil SE Bond and G Premio Bond by Self Etch method.
Development and Validation of HPLC Determination of related Substances in A Novel Anticonvulsant agent Epimidin
Authors: Severina Hanna I. , Gubar Svitlana M. , Bezruk Ivan V. , Materiienko Anna S. , Ivanauskas Liudas , Bunyatyan Vera A. , Kovalenko Sergiy M. , Scupa Olha O. , Georgiyants Victoriya A.
Published: July 2021

1-(4-methoxyphenyl)-5-[2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-oxo-ethyl]pyrazolo[3,4-d]pyrimidin-4-one has been reported as a promising new anticonvulsant drug candidate with a code name “Epimidin”. A new HPLC method for the related substances determination of potential active pharmaceutical ingredient has been developed and validated. The method uses ACE C18 column (250x4.6mm, 5µm) and gradient elution. Mobile phase consisted of a mixture of methanol R (mobile phase A) and phosphate buffer solution with triethanolamine, adjusted to pH 7.0 (mobile phase B). During the analysis, the ratio of mobile phases was changing according to a gradient mode at a flow rate of 1ml/min. The DAD detection was set at 240nm. The method was validated according to the ICH guidelines and requirements of State Pharmacopoeia of Ukraine. Drug substance was thoroughly explored for stability assessments under various stress conditions such as high temperature, as well as the influence of strong acid and base and oxidizing agents. The obtained solutions were analyzed by HPLC and LC/MS. It has been shown that the substance Epimidin was not resistant to the action of peroxide, alkali and acid decomposition – the mentioned stress conditions lead to the formation of unidentified impurities.
Formulation and Evaluation of Pellets of natural Okra gum prepared by Extrusion and Spheronization
Authors: Yadav Hemant K S , Usman Shahnaz , Ramesh KVRNS , Islam Quamrul
Published: July 2021

The aim of the current study was to explore the possibility of preparing pellets of okra gum using extrusion and spheronization technique. Different formulations were prepared by altering the concentration of okra gum. Metronidazole was chosen as a model drug. The pellets were smooth and spherical in shape. FTIR and DSC spectra’s confirmed that there was no interaction between drug and polymer. The pellets were free-flowing and exhibited satisfactory flow characteristics along with good mechanical strength. Okra gum was able to control the drug release and around 90% drug was released in 8hrs. Pellets showed increase in swelling as the concentration of gum was increased. Mucoadhesion study exhibited that the prepared pellets had good mucoadhesive strength.
Development and Validation of the Analytical method for the estimation of a combination of 5-fluorouracil and Imiquimod by RP-HPLC
Authors: Tomar Bhupender , Sharma Ankita , Kumar Inder , Jain Sandeep , Ahirrao Pallavi
Published: July 2021

A simple, precise, and accurate reverse phase high performance liquid chromatographic method (RP-HPLC) was developed and validated for the estimation of the combination of 5- Fluorouracil (5-FU) and Imiquimod in active pharmaceutical ingredients (APIs). The method was carried out on Phenomenex C18 (250 × 4.6mm I.D., 5𝜇m) using isocratic elution mode. The mobile phase was used as Acetonitrile: 10mM potassium dihydrogen orthophosphate: triethylamine (40:59.9:0.1, v/v, pH 4.5 with orthophosphoric acid) and Water: ACN (50:50 v/v) was used as a diluent. The concentration of solvents was 1-20µg/ml and the volume of injection was 20µl with the flow rate of 1.2ml/min. The retention times for 5-FU and Imiquimod were found to be 1.9±0.5 and 6.6±0.5 min respectively. The absorption maxima of 5FU and Imiquimod were found 267nm and 227nm respectively. The method was validated as per ICH guidelines. All the data were found within the specified limits. The limit of detection (LOD) and limit of quantification (LOQ) of 5- Fluorouracil were found to be 0.015μg/mL and 0.048 μg/mL, respectively, and Imiquimod was found to be 0.078μg/mL and 0.237μg/mL, respectively. The method developed in the present study was found to be sensitive, specific, and precise and can be applied for the simultaneous estimation of 5-FU and Imiquimod.
Review of the impact Covid-19 has on the Psychosocial factors affecting Well-Being
Authors: FBSCH Sheila Menon , Bhagat Vidya
Published: July 2021

The COVID-19 pandemic has had a significant impact on the psychosocial factors that effect people globally. Particularly affected are children, students and health workers and the common symptoms identified are stress, anxiety disorders, depression and post-traumatic stress disorder. In addition, the various security measures implemented to ensure public safety have adversely affected relationships between people. This study directs public awareness to the value of psychotherapeutic support. Tele-therapy can be offered easily to people both at home or in the workplace, providing both cost effective and time sensitive solutions during times of crisis. The current review article provides an overview of the importance of maintaining psychological well-being during a pandemic and the identifies the role that empathetic communication has on wellbeing. The literature review was completed using electronic databases such as PubMed, Medline, and Scopus databases using the keywords covid-19, affected groups, affected relationships, psychology and its technological interventions, negative effects of pandemic so on.
UNILATERAL PROFOUND DEAFNESS – A POSSIBLE MECHANISM
Authors:   LOR Department, Georgiev Konstantin ,   MBAT Varna,   Military Medical Academy, Bulgaria., Pacholova Yana ,   Family Centre Pan, Psychological and Speech Therapy Practice, Varna, Bulgaria.
Published: July 2021

Purpose: To explain the clinical findings of patients with profound unilateral deafness who have recovered the hearing function after a combined treatment of hyperbaric oxygenation and dehydrant therapy. Material and method: 11 patients with profound sudden unilateral hearing loss above 90 dB SPL, intolerance to sounds similar to recruitment, at levels 10-20 dB above the hearing threshold (105-120 dB SPL), positive glycerol test and unexpected good recovery of hearing within 1-2 months are described. Results: All patients have perfect outcome results without the use of glucocorticoids. Conclusions: Based on articles about experiments with genetically modified animals and acquired deafness, we propose a possible mechanism of damage explaining the clinical findings and the favorable outcome of the disease – a disconnection between the tectorial membrane and stereocilia. Thus mechano-electrical transducer (MET) of hair cells cannot be activated. The combined use of hyperbaric oxygenation and dehydrant medications can lead to recovery of the hearing function.
La IA y la ciudadanía digital
Authors: Crovetto Angel
Published: July 2021

Los avances tecnológicos en el campo de la Inteligencia Artificial ponen al debate la capacidad de ejercer, de forma efectiva, la ciudadanía digital. El propósito de este artículo es brindar una línea de reflexión sobre los problemas éticos y de ciudadanía digital entorno a la nueva Estrategia Nacional de Inteligencia Artificial (ENIA) propuesta por el Estado Peruano, para ello hemos estudiado al detalle la ENIA identificando las posibles oportunidades de mejora de la Estrategia. Finalmente consideramos que la propuesta de la ENIA contribuye al debate poniendo en relevancia la necesidad de promover la ciudadanía digital.
Comunidades humanistas ante el transhumanismo
Authors: Gómez Marcela
Published: July 2021

El artículo inicia con dos preguntas provenientes de un experimento informal cuyo propósito fue observar la reacción cotidiana ante el término transhumanismo. Acto seguido, el término se define de manera breve para dar paso a varias referencias que a lo largo de la historia han sugerido un interés por preservar la vida humana trascendiendo las barreras de la corporeidad. Posteriormente, y siguiendo con el llamado de estas fuentes, se mencionan algunos modelos más detallados en torno a las alternativas para la modificación de la corporeidad humana en aras de su trascendencia, los cuales tienen como punto en común la adaptación a un hábitat modificado. Finalmente, se habla de la humanización como camino para lograr este proceso de adaptación a un hábitat en permanente cambio.