bluuebunny/crossref_metadata_2025 huggingface dataset:
Doing and feeling together in older age: self-worth and belonging through social creative activities
Authors: Wood Emma H. , Jepson Allan , Stadler Raphaela
Published: November 2021

The potential for art activities to help in alleviating loneliness is explored through a focus on older women's regular attendance at creative social activities. We apply the concept of perceived emotional synchrony to understand how weekly craft group sessions enable feelings of belonging and self-worth to develop in older women. Using a multi-site six-month study of 62 women aged 70+ attending social creative activities, our multi-stage research design captures the experiences of these women through observation and narrative group discussions held weekly. Our findings show that feelings of belonging and self-worth developed over a relatively short time. In particular, social integration and identity fusion were found to occur as a result of the emotional synchrony engendered via a regular shared activity, out of the home, and requiring some challenge and creativity. We propose a virtuous cycle model to explain the value in such activities and discuss the wider implications for wellbeing in older age. Perceived emotional synchrony has not been used before to explore the mechanisms through which social creative activities form lasting benefits for older women. Our research highlights the importance of feeling at one with others in improving feelings of belonging and self-worth and indicates how a variety of social creative experiences could be designed to enable this.
Young minds’ quest for regularity: Evidence from the Turkish causative
Authors: NAKİPOĞLU Mine , UZUNDAĞ Berna A. , SARIGÜL Özge
Published: November 2021

Children's remarkable ability to generalize beyond the input and the resulting overregularizations/ irregularizations provide a platform for a discussion of whether morphology learning uses analogy-based, rule-based, or statistical learning procedures. The present study, testing 115 children (aged 3 to 10) on an elicited production task, investigated the acquisition of the irregular distribution in the Turkish causative. Results showed that in early acquisition, to pin down the four causative suffixes, children engaged in comparisons between analogous exemplars. Thereafter to tackle the irregularity in two of the suffixes, children entertained competing hypotheses that yielded overregularizations and irregularizations. Overregularizations were instances of abstraction across the input based on type frequency; irregularizations were attempts to default to erroneous micro-generalizations. Negative correlation between errors and verb frequency suggested that recovery from errors was sensitive to token frequency. The overgeneralize-then-recover pattern that emerged in the acquisition of causative supported an integrated account of the roles of analogy, abstraction, and frequency in morphology learning.
Challenges and Strategies to Adapt the Provision of Support Services to Older Adults and Caregivers During the COVID-19 Pandemic: The Perspective of Community Organizations
Authors: Poulin Valérie , Provencher Véronique , Nicole Mélodie , Shea Victoria , Aubin Ginette , Beaulieu Marie , Bier Nathalie , Fortier Julie , Giroux Dominique , Levasseur Mélanie , Lord Marie-Michèle
Published: November 2021

This study documented the provision of services and issues experienced by community organizations supporting older adults and caregivers in the province of Quebec during the coronavirus disease (COVID-19) pandemic, as well as promising strategies to adapt the provision of services in this context. A cross-sectional electronic survey using open- and closed-ended questions was conducted in July 2020. Almost three-quarters of the 307 respondents (71.4%) reported having maintained services at least partially throughout the lockdown, and the majority (85.3%) adapted their services. Among key challenges, participants reported difficulties identifying and supporting older adults at greater risk of vulnerability (54.8%), managing health risks for service users (60.2%), and recruiting volunteers (59.5%). Promising strategies included strategies to reach out to older adults and understand their needs (e.g., systematic phone calls) in addition to direct interventions supporting them (e.g., activities promoting social ties); implementing prevention and protection measures; accessing and using technologies; human resources management (e.g., recruiting new volunteers); finding financial support for their organization; developing intersectoral partnerships (e.g., multisectoral crisis cell); and promoting a positive view of older adults. The integration of multiple perspectives from different stakeholders may help identify strategies potentially transferable to other crises in order to meet older adults’ needs.
Impact of COVID-19 on Relationship-Centred Residential Dining Practices
Authors: Keller Heather H. , Trinca Vanessa , Dakkak Hana , Wu Sarah A. , Bovee Sabrina , Carrier Natalie , Cammer Allison , Lengyel Christina , O’Rourke Hannah M. , Rowe Natalie , Slaughter Susan E. , Quiring Suzanne
Published: November 2021

This study describes changes in dining practices and provider perspectives on meal-related challenges due to the coronavirus disease (COVID-19) pandemic. An online survey was disseminated between July and September 2020 through stakeholder networks and social media with 1,036 respondents. Altered dining practices included residents eating in rooms (54.3%), spacing residents in common areas for meals (69.3%), and disposable dish use (44.9%). The most common mealtime challenges were reduced socializing opportunities at meals (29.3%), inadequate staffing (22.8%), reduced family/volunteer help (16.7%), and assisting residents to eat (10.5%). Many participants (72.2%) felt conflict balancing safety and relationship-centred care. Geographic region, home size, building age, respondent’s job title, pre-pandemic relationship-centred practices, and mealtime satisfaction, and some pandemic-initiated practices were associated with mealtime challenges and feeling conflicted in binary logistic regression analyses. Considering trade-offs between safety and relational aspects of mealtimes during the pandemic is crucial.
Shaping new interregionalism: The EU-Singapore Free Trade Agreement and beyond
Authors: Hsieh Pasha L.
Published: November 2021

The article examines the theoretical concept of interregionalism in the context of the evolving framework between the European Union (EU) and the Association of Southeast Asian Nations (ASEAN). As the EU’s first free trade agreement (FTA) with an ASEAN country, the EU-Singapore FTA is a pathfinder agreement that signifies a new phase of interregionalism and the EU’s new Asia strategy after the Treaty of Lisbon. The article argues that the innovative designs of the EU-Singapore FTA will shape the normative development of EU-ASEAN relations in the post-pandemic era. It also cautions that a comparative analysis of EU and US agreements reveals deficiencies in the FTA that require remedies. To buttress the contention, key provisions on ASEAN cumulative rules of origin, banking and legal services and non-tariff barriers are analysed in light of contemporary Asian agreements. The research further provides insight into the effectiveness of new-generation rules on geographical indications, competition, and investor-state arbitration and mediation. Hence, the findings contribute to the understanding of interregionalism and the EU’s Asia-Pacific trade and investment agreements from global and interdisciplinary perspectives.
COVID-19 vaccine hesitancy among university students in Lebanon
Authors: Bou Hamdan M. , Singh S. , Polavarapu M. , Jordan T. R. , Melhem N. M.
Published: November 2021

Little is known about the decision-making process of college students in Lebanon regarding coronavirus disease-2019 (COVID-19) vaccination. The aim of this study was to identify factors predicting behavioural intentions of students enrolled at the American University of Beirut to obtain a COVID-19 vaccine. A total of 3805 students were randomly selected. Participants were divided into three groups: vaccine accepting (willing to take or already took the vaccine), vaccine hesitant (hesitant to take the vaccine) and vaccine resistant (decided not to take the vaccine). Overall, participants were vaccine accepting (87%), with 10% and 3% being hesitant and resistant, respectively. Vaccine hesitancy was significantly associated with nationality, residency status and university rank. Participants who believed the vaccine was safe and in agreement with their personal views were less likely to be hesitant. Participants who did not receive the flu vaccine were more hesitant than those who did. Moreover, a significant association between hesitancy and agreement with conspiracies was observed. A high level of knowledge about COVID-19 disease and vaccine resulted in lower odds of vaccine resistance among students. The factors identified explaining each of the three vaccine intention groups can be used as core content for health communication and social marketing campaigns to increase the rate of COVID-19 vaccination.
Socioeconomic disadvantage and parental mood/affective problems links negative parenting and executive dysfunction in children born very preterm
Authors: Lean Rachel E. , Gerstein Emily D. , Smyser Tara A. , Smyser Christopher D. , Rogers Cynthia E.
Published: November 2021

Poverty increases the risk of poorer executive function (EF) in children born full-term (FT). Stressors associated with poverty, including variability in parenting behavior, may explain links between poverty and poorer EF, but this remains unclear for children born very preterm (VPT). We examine socioeconomic and parental psychosocial adversity on parenting behavior, and whether these factors independently or jointly influence EF in children born VPT. At age five years, 154 children (VPT = 88, FT = 66) completed parent-child interaction and EF tasks. Parental sensitivity, intrusiveness, cognitive stimulation, and positive and negative regard were coded with the Parent-Child Interaction Rating Scale. Socioeconomic adversity spanned maternal demographic stressors, Income-to-Needs ratio, and Area Deprivation Index. Parents completed measures of depression, anxiety, inattention/hyperactivity, parenting stress, and social-communication interaction (SCI) problems. Parental SCI problems were associated with parenting behavior in parents of children born VPT, whereas socioeconomic adversity was significant in parents of FT children. Negative parenting behaviors, but not positive parenting behaviors, were related to child EF. This association was explained by parental depression/anxiety symptoms and socioeconomic adversity. Results persisted after adjustment for parent and child IQ. Findings may inform research on dyadic interventions that embed treatment for parental mood/affective symptoms and SCI problems to improve childhood EF.
Opera History, the Travel Edition
Authors: Hicks Jonathan
Published: November 2021

This book has been in my bag for a long time and, on reflection, I am glad that I have read it gradually. When the central premise is so simple – Grand Opera Outside Paris is, indeed, about Grand Opera outside Paris – the payback comes in the detail of individual chapters and the slow emergence of a Europe-wide survey of encounter and exchange. The volume's editor, Jens Hesselager, provides an erudite and generous introduction, beginning with the familiar difficulty of defining grand opera and the importance of attending to specific performance contexts. In the first instances, of course, this meant the Paris Opéra, and Hesselager draws our attention to Sarah Hibberd's observation that the coherence of the genre was initially established ‘more through the licensing requirements of [this] institution than by [any] specific dramatic content’ (1). From here, the introduction gently encourages us to look outward.
On the global existence and qualitative behaviour of one-dimensional solutions to a model for urban crime
Authors: RODRIGUEZ NANCY , WINKLER MICHAEL
Published: November 2021

We consider the no-flux initial-boundary value problem for the cross-diffusive evolution system:
\begin{eqnarray*} \left\{ \begin{array}{ll} u_t = u_{xx} - \chi \big(\frac{u}{v} \partial_x v \big)_x - uv +B_1(x,t), \qquad & x\in \Omega, \ t>0, \\[1mm] v_t = v_{xx} +uv - v + B_2(x,t), \qquad & x\in \Omega, \ t>0, \end{array} \right. \end{eqnarray*}
which was introduced by Short et al. in [40] with
$\chi=2$
to describe the dynamics of urban crime.

In bounded intervals
$\Omega\subset\mathbb{R}$
and with prescribed suitably regular non-negative functions
$B_1$
and
$B_2$
, we first prove the existence of global classical solutions for any choice of
$\chi>0$
and all reasonably regular non-negative initial data.

We next address the issue of determining the qualitative behaviour of solutions under appropriate assumptions on the asymptotic properties of
$B_1$
and
$B_2$
. Indeed, for arbitrary
$\chi>0$
, we obtain boundedness of the solutions given strict positivity of the average of
$B_2$
over the domain; moreover, it is seen that imposing a mild decay assumption on
$B_1$
implies that u must decay to zero in the long-term limit. Our final result, valid for all
$\chi\in\left(0,\frac{\sqrt{6\sqrt{3}+9}}{2}\right),$
which contains the relevant value
$\chi=2$
, states that under the above decay assumption on
$B_1$
, if furthermore
$B_2$
appropriately stabilises to a non-trivial function
$B_{2,\infty}$
, then (u,v) approaches the limit
$(0,v_\infty)$
, where
$v_\infty$
denotes the solution of
\begin{eqnarray*} \left\{ \begin{array}{l} -\partial_{xx}v_\infty + v_\infty = B_{2,\infty}, \qquad x\in \Omega, \\[1mm] \partial_x v_{\infty}=0, \qquad x\in\partial\Omega. \end{array} \right. \end{eqnarray*}
We conclude with some numerical simulations exploring possible effects that may arise when considering large values of
$\chi$
not covered by our qualitative analysis. We observe that when
$\chi$
increases, solutions may grow substantially on short time intervals, whereas only on large timescales diffusion will dominate and enforce equilibration.
The Effect of Heat Events on Prehospital and Retrieval Service Utilization in Rural and Remote Areas: A Scoping Review
Authors: O’Donnell Elen , Honan Bridget , Quilty Simon , Schultz Rebecca
Published: November 2021

Introduction:

It is well-established that heatwaves increase demand for emergency transport in metropolitan areas; however, little is known about the impact of heat events on demand for prehospital retrieval services in rural and remote areas, or how heatwaves are defined in this context.

Inclusion Criteria:

Papers were eligible for inclusion if they reported on the impact of a heat event on the activity of a prehospital and retrieval service in a rural or remote area.

Methods:

A search of PubMed, Cochrane, Science Direct, CINAHL, and Google Scholar databases was undertaken on August 18, 2020 using search terms related to emergency medical transport, extreme heat, and rural or remote. Data relevant to the impact of heat on retrieval service activity were extracted, as well as definitions of extreme heat.

Results:

Two papers were identified, both from Australia. Both found that heat events increased the number of road ambulance call-outs. Both studies used the Excess Heat Factor (EHF) to define heatwave periods of interest.

Conclusions:

This review found almost no primary literature on demand for prehospital retrieval services in rural and remote areas, and no data specifically related to aeromedical transport. The research did recognize the disproportionate impact of heat-related increase in service demand on Australian rural and regional health services. With the effects of climate change already being felt, there is an urgent need for more research and action in this area.
Nutrient comparisons of margarine/margarine-like products, butter blend products and butter in the US marketplace in 2020 post-FDA ban on partially hydrogenated oils
Authors: Weber Cecily , Harnack Lisa , Johnson Abigail , Jasthi Bhaskarani , Pettit Janet , Stevenson Jennifer
Published: November 2021

Objective:

To evaluate the fatty acid profiles and relevant vitamin and mineral compositions of margarine/margarine-like products and butter blend products available in the US marketplace and to compare with butter.

Design:

Analysis of the food and nutrient composition information available for margarine/margarine-like products, butter blend products and butter in the 2021 version of the University of Minnesota Nutrition Coordinating Center (NCC) Food and Nutrient Database.

Setting:

The US retail food marketplace in 2020.

Participants:

A selection of eighty-three margarine/margarine-like or butter blend products available in the USA in 2020 and regular and whipped butter (both salted and unsalted).

Results:

All products contained no or negligible amounts of trans fat. Mean daily values (DV) for SFA per 1 tablespoon ranged from 11 % for margarine/margarine-like tub and squeeze products to 18 % for margarine/margarine-like stick products and butter blend products. In contrast, one tablespoon butter provides 36 % of the DV for SFA. Results from ANOVA comparing the percent of total fat from SFA, PUFA and MUFA by product type indicated significant differences for SFA (P < 0·01) and PUFA (P < 0·01), but not MUFA (P = 0·07).

Conclusions:

Leading brands of margarine/margarine-like and butter blend products examined in this study were found to be in greater alignment with current dietary recommendations for fatty acids and cholesterol than butter. Margarine/margarine-like tub and squeeze products were found to be optimal over margarine/margarine-like stick products and butter blend products. Future research should include an examination of private label products.
Accurate Morphology Characterization Using Atomic Force Microscopy via Vertical Drift Correction and Illusory Slope Elimination
Authors: Wu Yinan , Fang Yongchun , Fan Zhi , Liu Cunhuan
Published: November 2021

Thanks to the ability to perform imaging and manipulation at the nanoscale, atomic force microscopy (AFM) has been widely used in biology, materials, chemistry, and other fields. However, as common error sources, vertical drift and illusory slope severely impair AFM imaging quality. To address this issue, this paper proposes a robust algorithm to synchronously correct the image distortion caused by vertical drift and slope, thus achieving accurate morphology characterization. Specifically, to eliminate the damage of abnormal points and feature areas on the correction accuracy, the laser spot voltage error acquired in the AFM scanning process is first utilized to preprocess the morphology height data of the sample, so as to obtain the refined alternative data suitable for line fitting. Subsequently, this paper proposes a novel line fitting algorithm based on sparse sample consensus, which accurately simulates vertical drift and slope in the cross-sectional profile of the topographic image, thereby achieving effective correction of the image distortion. In the experiments and applications, a nanoscale optical grating sample and a biological cell sample are adopted to perform topography imaging and distortion correction, so as to verify the ability of the proposed algorithm to promote AFM imaging quality.
Constraint Answer Set Programming: Integrational and Translational (or SMT-based) Approaches
Authors: LIERLER YULIYA
Published: November 2021

Constraint answer set programming or CASP, for short, is a hybrid approach in automated reasoning putting together the advances of distinct research areas such as answer set programming, constraint processing, and satisfiability modulo theories. CASP demonstrates promising results, including the development of a multitude of solvers: acsolver, clingcon, ezcsp, idp, inca, dingo, mingo, aspmt2smt, clingo[l,dl], and ezsmt. It opens new horizons for declarative programming applications such as solving complex train scheduling problems. Systems designed to find solutions to constraint answer set programs can be grouped according to their construction into, what we call, integrational or translational approaches. The focus of this paper is an overview of the key ingredients of the design of constraint answer set solvers drawing distinctions and parallels between integrational and translational approaches. The paper also provides a glimpse at the kind of programs its users develop by utilizing a CASP encoding of Traveling Salesman problem for illustration. In addition, we place the CASP technology on the map among its automated reasoning peers as well as discuss future possibilities for the development of CASP.
Colonialism, Cosmopolitanism, and Nationalism: The Performativity of Western Music Endeavours in Interwar Shanghai
Authors: YANG HON-LUN HELAN
Published: November 2021

This article examines the meaning of Western music performances in interwar Shanghai through the theoretical framework of performativity that originated in John Austin's speech act and Judith Butler's notion of identity as performed. The early concerts of the Shanghai Municipal Orchestra (SMO), I suggest, were an assertion of settler sovereignty in a treaty port such as Shanghai. Therefore, Chinese musicians performing Western music – propagated through the establishment of the National Conservatory of Music by Chinese elites in Shanghai's French Settlement in 1927 – was the embodiment of three contradictory ideals: colonialism, nationalism, and cosmopolitanism. Zooming in on four SMO concerts that featured Chinese musicians in 1929, I argue that they were sites of identity and power negotiation, the SMO and the Chinese musicians asserting quite distinct performative utterances. On the one hand, the performing Chinese body enacted the cosmopolitan outlook that the Municipal Council was eager to project, not only for the sake of ideology but also to increase SMO's concert revenue by appealing to the increasing number of Chinese concert attendees. On the other hand, it meant national glory to Chinese residents in Shanghai, marking Chinese musicians participating in a global musical network. Lastly, this study draws attention to the diverse geographies of Western music in the twentieth century and its coeval development beyond the West, testifying to the timely need for a global music history in which the musicking of Western music in so many Asian cities should be interwoven into its narrative.
Internal Migration and Sectoral Shift in the Nineteenth-Century United States
Authors: MacDonald Daniel
Published: November 2021

We study the relationship between internal migration and industrialization in the United States between 1850 and 1880. We use the Linked Representative Samples from IPUMS and find significant amounts of rural-urban and urban-urban migration in New England. Rural-urban migration was mainly driven by agricultural workers shifting to manufacturing occupations. Urban-urban migration was driven by foreign-born workers in manufacturing. We argue that rural-urban migration was a significant factor in US economic development and the structural transformation from agriculture to manufacturing.
Insight Into Formation Processes of Layered Ejecta Craters on Mars From Thermophysical Observations
Authors: Hoover R. H. , Robbins S. J. , Putzig N. E. , Riggs J. D. , Hynek B. M.
Published: November 2021

Understanding the morphological characteristics of craters that are indicative of their formation environment can provide insight into surface geology. Layered ejecta (LE) craters, found on Mars and some other planetary bodies, have been hypothesized to have formed as a result of either interaction with subsurface volatiles (volatile fluidization model) and/or with the atmosphere (atmospheric entrainment model). Formation of LE craters by either model should result in different grain size distributions throughout the ejecta deposit. Using thermal inertia to infer surface properties, we investigated LE craters and their ejecta deposits in an effort to distinguish between possible LE formation processes on Mars. We used thermophysical properties of crater ejecta to determine grain size distribution, to model horizontal mixtures and vertical layering, and to identify materials present within the ejecta. We assessed the thermal properties of 50 uniformly sampled LE craters using Mars Odyssey Thermal Emission Imaging System (THEMIS) and Mars Global Surveyor Thermal Emission Spectrometer (TES) data. Our THEMIS analysis identifies 12 craters with grain size distributions consistent with the volatile fluidization model, 3 craters that have characteristics potentially associated with either model, and 22 craters that do not exhibit characteristics matching either model. Our TES analysis identifies 11 craters with characteristics consistent with the volatile fluidization model and 8 craters that are consistent with the atmospheric entrainment model. While some observations of grain size distributions provide evidence for either or both models, there is not overwhelming support for either model, potentially due to uncertainties of derived thermal inertia data.
Strengthening of Calcite Assemblages Through Chemical Complexation Reactions
Authors: Choens R. C. , Wilson J. , Ilgen A. G.
Published: November 2021

Utilization of subsurface reservoirs, including fluid extraction/injection, can induce stress changes and modify in‐situ chemical equilibrium causing subcritical fracturing and deformation. Here, we show that chemical complexation reactions at the newly created fracture surfaces within the crack tip limit fracturing during consolidation of granular calcite assemblages. Previously, we showed that analogous chemical complexation reactions can increase in‐situ fracture toughness in pre‐fractured single crystal calcite. To test the chemical complexation effect under subsurface conditions, we consolidated samples under increasing hydrostatic pressure to induce widespread intergranular fracturing in the presence of fluid containing common anions. Measured consolidation, acoustic emissions, and microfracturing demonstrate that deformation correlates with complexation affinity for calcium in calcite and aqueous anions. We observed that deformation is lowest in the presence of strongly complexing anions (e.g., sulphate), provided sufficient anion diffusion rates. This understanding is important for predicting reservoir effective strength in the presence of complex aqueous fluids.
The Missing Magmatic Arc in a Long‐Lived Ocean From the Western Kunlun‐ Pamir Paleo‐Tethys Realm
Authors: Tang Gong‐Jian , Cawood Peter A. , Wyman Derek A. , Dan Wei , Wang Qiang , Yang Ya‐Nan
Published: November 2021

The evolution of the western Kunlun‐Pamir region involved the opening and closing of several branches of the Paleo‐Tethys Ocean, although the specific timing of these events is poorly constrained. Here, we present a synthesis of sedimentary, magmatic, and metamorphic records associated from the Mazar‐Kangxiwa suture zone in the western Kunlun‐Pamir that is generally regarded as the main Paleo‐Tethys Ocean suture. These data show that the Paleo‐Tethyan oceanic basin opened at ca. 340 Ma and closed by ca. 250 Ma, and there is no record of a magmatic arc between ca. 300–250 Ma. The absence of a magmatic arc was a result of oceanic crust underthrusting, rather than oceanic subduction, which is consistent with a narrow back‐arc basin. Our study provides an important example of how an oceanic basin opened and closed without oceanic subduction, and highlights a potential mechanism to account for the absence of a magmatic arc.
Indirect Measurements of the Composition of Ultrafine Particles in the Arctic Late‐Winter
Authors: Myers Deanna C. , Lawler Michael J. , Mauldin Roy L. , Sjostedt Steven , Dubey Manvendra , Abbatt Jonathan , Smith James N.
Published: November 2021

We present indirect measurements of size‐resolved ultrafine particle composition conducted during the Ocean‐Atmosphere‐Sea Ice‐Snowpack (OASIS) Campaign in Utqiagvik, Alaska, during March 2009. This study focuses on measurements of size‐resolved particle hygroscopicity and volatility measured over two periods of the campaign. During a period that represents background conditions in this location, particle hygroscopic growth factors (HGF) at 90% relative humidity ranged from 1.45 to 1.51, which combined with volatility measurements suggest a mixture of ∼30% ammoniated sulfates and ∼70% oxidized organics. Two separate regional ultrafine particle growth events were also observed during this campaign. Event 1 coincided with elevated levels of H2SO4 and solar radiation. These particles were highly hygroscopic (HGF = 2.1 for 35 nm particles), but were almost fully volatilized at 160 °C. The air masses associated with both events originated over the Arctic Ocean. Event 1 was influenced by the upper marine boundary layer (200–350 m AGL), while Event 2 spent more time closer to the surface (50–150 m AGL) and over open ocean leads, suggesting marine influence in growth processes. Event 2 particles were slightly less hygroscopic (HGF = 1.94 for 35 nm and 1.67 for 15 nm particles), and similarly volatile. We hypothesize that particles formed during both events contained 60–70% hygroscopic salts by volume, with the balance for Event 1 being sulfates and oxidized organics for Event 2. These observations suggest that primary sea spray may be an important initiator of ultrafine particle formation events in the Arctic late‐winter, but a variety of processes may be responsible for condensational growth.
Implementation and Evaluation of a Unified Turbulence Parameterization Throughout the Canopy and Roughness Sublayer in Noah‐MP Snow Simulations
Authors: Abolafia‐Rosenzweig Ronnie , He Cenlin , Burns Sean P. , Chen Fei
Published: November 2021

The Noah‐MP land surface model (LSM) relies on the Monin‐Obukhov (M‐O) Similarity Theory (MOST) to calculate land‐atmosphere exchanges of water, energy, and momentum fluxes. However, MOST flux‐profile relationships neglect canopy‐induced turbulence in the roughness sublayer (RSL) and parameterize within‐canopy turbulence in an ad hoc manner. We implement a new physics scheme (M‐O‐RSL) into Noah‐MP that explicitly parameterizes turbulence in RSL. We compare Noah‐MP simulations employing the M‐O‐RSL scheme (M‐O‐RSL simulations) and the default M‐O scheme (M‐O simulations) against observations obtained from 647 Snow Telemetry (SNOTEL) stations and two AmeriFlux stations in the western United States. M‐O‐RSL simulations of snow water equivalent (SWE) outperform M‐O simulations over 64% and 69% of SNOTEL sites in terms of root‐mean‐square‐error (RMSE) and correlation, respectively. The largest improvements in skill for M‐O‐RSL occur over closed shrubland sites, and the largest degradations in skill occur over deciduous broadleaf forest sites. Differences between M‐O and M‐O‐RSL simulated snowpack are primarily attributable to differences in aerodynamic conductance for heat underneath the canopy top, which modulates sensible heat flux. Differences between M‐O and M‐O‐RSL within‐canopy and below‐canopy sensible heat fluxes affect the amount of heat transported into snowpack and hence change snowmelt when temperatures are close to or above the melting point. The surface energy budget analysis over two AmeriFlux stations shows that differences between M‐O and M‐O‐RSL simulations can be smaller than other model biases (e.g., surface albedo). We intend for the M‐O‐RSL physics scheme to improve performance and uncertainty estimates in weather and hydrological applications that rely on Noah‐MP.
Improving a Biogeochemical Model to Simulate Microbial‐Mediated Carbon Dynamics in Agricultural Ecosystems
Authors: Deng Jia , Frolking Steve , Bajgain Rajen , Cornell Carolyn R. , Wagle Pradeep , Xiao Xiangming , Zhou Jizhong , Basara Jeffrey , Steiner Jean , Li Changsheng
Published: November 2021

Soil microbes drive decomposition of soil organic matter (SOM) and regulate soil carbon (C) dynamics. Process‐based models have been developed to quantify changes in soil organic carbon (SOC) and carbon dioxide (CO2) fluxes in agricultural ecosystems. However, microbial processes related to SOM decomposition have not been, or are inadequately, represented in these models, limiting predictions of SOC responses to changes in microbial activities. In this study, we developed a microbial‐mediated decomposition model based on a widely used biogeochemical model, DeNitrification‐DeComposition (DNDC), to simulate C dynamics in agricultural ecosystems. The model simulates organic matter decomposition, soil respiration, and SOC formation by simulating microbial and enzyme dynamics and their controls on decomposition, and considering impacts of climate, soil, crop, and farming management practices (FMPs) on C dynamics. When evaluated against field observations of net ecosystem CO2 exchange (NEE) and SOC change in two winter wheat systems, the model successfully captured both NEE and SOC changes under different FMPs. Inclusion of microbial processes improved the model's performance in simulating peak CO2 fluxes induced by residue return, primarily by capturing priming effects of residue inputs. We also investigated impacts of microbial physiology, SOM, and FMPs on soil C dynamics. Our results demonstrated that residue or manure input drove microbial activity and predominantly regulated the CO2 fluxes, and manure amendment largely regulated long‐term SOC change. The microbial physiology had considerable impacts on the microbial activities and soil C dynamics, emphasizing the necessity of considering microbial physiology and activities when assessing soil C dynamics in agricultural ecosystems.
Stratospheric X‐Rays Detected at Midlatitudes With a Miniaturized Balloon‐Borne Microscintillator‐PiN Diode System
Authors: Aplin K. L. , Marlton G. J. , Race V.
Published: November 2021

A miniaturized scintillator (“microscintillator”), was flown on a meteorological radiosonde to observe energetic particles in the lower atmosphere. A PiN diode was used to measure the light from the microscintillator to count rates and energies of ionizing radiation from the ground up to the stratosphere (32 km). The flight, over the southern UK on August 27, 2018, occurred during a geomagnetic storm. Low‐energy (50–150 keV) particles in the stratosphere were detected in addition to the usual signal from higher‐energy cosmic rays. Unusually for these miniaturized radiosonde systems, which are designed to be disposable, the payload was retrieved. This allowed for re‐calibration of the microscintillator, which confirmed the low‐energy particle detection. Laboratory tests excluded thermal effects on the microscintillator instrument as the origin of the signal. Data from the NOAA POES spacecraft offer the explanation that the microscintillator detected bremstrahhlung X‐rays from energetic electron precipitation (EEP). EEP events may affect weather and climate through a range of physical mechanisms, and this midlatitude observation, well away from the auroral oval, extends the region over which meteorological effects of EEPs need to be assessed. Our findings underline the value of balloon measurements in providing rapid response to space weather events. The energy‐discriminating and altitude‐sensitive capability of the microscintillator augments spacecraft observations from below.
Decreased expression of ATF3, orchestrated by β-catenin/TCF3, miR-17-5p and HOXA11-AS, promoted gastric cancer progression via increased β-catenin and CEMIP
Authors: Xie Guohua , Dong Ping , Chen Hui , Xu Ling , Liu Yi , Ma Yanhui , Zheng Yingxia , Yang Junyao , Zhou Yunlan , Chen Lei , Shen Lisong
Published: November 2021

ATF3 has been reported to be dysregulated in various cancers and involved in various steps of tumorigenesis. However, the mechanisms underlying the abnormal expression of ATF3 and its biological function in gastric cancer (GC) have not been well investigated. Here, we report ATF3 as one of the key regulators of GC development and progression. Patients with low ATF3 expression had shorter survival and a poorer prognosis. In vitro and in vivo assays investigating ATF3 alterations revealed a complex integrated phenotype that affects cell growth and migration. Strikingly, high-throughput sequencing and microarray analysis of cells with ATF3 silencing or of ATF3-low GC tissues indicated alterations in the Wnt signaling pathway, focal adhesions and adherens junctions. Mechanistically, the expression of β-catenin and cell migration inducing hyaluronidase 1 (CEMIP) was significantly upregulated in GC cells with downregulated ATF3, which was synergistically repressed by the β-catenin/TCF3 signaling axis and noncoding RNA miR-17-5p and HOXA11-AS. In addition, we found that WDR5 expression was promoted by TCF3 and is involved in miR-17-5p and HOXA11-AS activation in GC cells. Taken together, our findings revealed the mechanism of ATF3 downregulation and its biological role in regulating the expression of Wnt signaling-related genes during GC progression, suggesting new informative biomarkers of malignancy and therapeutic directions for GC patients.
LncRNA RP11-89 facilitates tumorigenesis and ferroptosis resistance through PROM2-activated iron export by sponging miR-129-5p in bladder cancer
Authors: Luo Wenjie , Wang Jun , Xu Wenhao , Ma Chunguang , Wan Fangning , Huang Yongqiang , Yao Mengfei , Zhang Hailiang , Qu Yuanyuan , Ye Dingwei , Zhu Yiping
Published: November 2021

Long non-coding RNAs (lncRNAs) act as important regulators of tumorigenesis and development in bladder cancer. However, the underlying molecular mechanisms remain elusive. We previously identified a novel lncRNA signature related to immunity and progression in bladder cancer. Here we further explored the function of RP11-89, a lncRNA discovered in the previous signature. Loss- and gain-of function experiments were performed using CCK-8 assay, flow cytometry, Transwell assays, scratch tests and subcutaneous nude mouse models. High-throughput RNA sequencing was conducted to identify dysregulated genes in bladder cancer cells with RP11-89 knockdown or overexpression. Regulation of RP11-89 on miR-129-5p and PROM2 was explored through luciferase reporter assay, RIP assay and RNA pull-down assay. RP11-89 promoted cell proliferation, migration and tumorigenesis and inhibited cell cycle arrest via the miR-129-5p/PROM2 axis. We found that RP11-89 “sponges” miR-129-5p and upregulates PROM2. Elevated PROM2 in cells was associated with attenuated ferroptosis through iron export, formation of multivesicular bodies and less mitochondrial abnormalities. We demonstrated that RP11-89 is a novel tumorigenic regulator that inhibits ferroptosis via PROM2-activated iron export. RP11-89 may serve as a potential biomarker for targeted therapy in bladder cancer.
ARSD, a novel ERα downstream target gene, inhibits proliferation and migration of breast cancer cells via activating Hippo/YAP pathway
Authors: Lin Yun , Li Chun , Xiong Wei , Fan Liping , Pan Hongchao , Li Yaochen
Published: November 2021

Advanced breast cancer (BC), especially basal like triple-negative BC (TNBC), is a highly malignant tumor without viable treatment option, highlighting the urgent need to seek novel therapeutic targets. Arylsulfatase D (ARSD), localized at Xp22.3, is a female-biased gene due to its escaping from X chromosome inactivation (XCI). Unfortunately, no systematic investigation of ARSD on BC has been reported. In this study, we observed that ARSD expression was positively related to ERα status either in BC cells or tissue specimens, which were associated with good prognosis. Furthermore, we found a set of hormone-responsive lineage-specific transcription factors, FOXA1, GATA3, ERα, directly drove high expression of ARSD through chromatin looping in luminal subtype BC cells. Opposingly, ARSD still subjected to XCI in TNBC cells mediated by Xist, CpG islands methylation, and inhibitory histone modification. Unexpectedly, we also found that ectopic ARSD overexpression could inhibit proliferation and migration of TNBC cells by activating Hippo/YAP pathway, indicating that ARSD may be a molecule brake on ERα signaling pathway, which restricted ERα to be an uncontrolled active status. Combined with other peoples’ researches that Hippo signaling maintained ER expression and ER + BC growth, we believed that there should exist a regulative feedback loop formation among ERα, ARSD, and Hippo/YAP pathway. Collectively, our findings will help filling the knowledge gap about the influence of ARSD on BC and providing evidence that ARSD may serve as a potential marker to predict prognosis and as a therapeutic target.
Compound jetting from bubble bursting at an air-oil-water interface
Authors: Ji Bingqiang , Yang Zhengyu , Feng Jie
Published: November 2021

Bursting of bubbles at a liquid surface is ubiquitous in a wide range of physical, biological, and geological phenomena, as a key source of aerosol droplets for mass transport across the interface. However, how a structurally complex interface, widely present in nature, mediates the bursting process remains largely unknown. Here, we document the bubble-bursting jet dynamics at an oil-covered aqueous surface, which typifies the sea surface microlayer as well as an oil spill on the ocean. The jet tip radius and velocity are altered with even a thin oil layer, and oily aerosol droplets are produced. We provide evidence that the coupling of oil spreading and cavity collapse dynamics results in a multi-phase jet and the follow-up droplet size change. The oil spreading influences the effective viscous damping, and scaling laws are proposed to quantify the jetting dynamics. Our study not only advances the fundamental understanding of bubble bursting dynamics, but also may shed light on the airborne transmission of organic matters in nature related to aerosol production.
Extracellular LGALS3BP regulates neural progenitor position and relates to human cortical complexity
Authors: Kyrousi Christina , O’Neill Adam C. , Brazovskaja Agnieska , He Zhisong , Kielkowski Pavel , Coquand Laure , Di Giaimo Rossella , D’ Andrea Pierpaolo , Belka Alexander , Forero Echeverry Andrea , Mei Davide , Lenge Matteo , Cruceanu Cristiana , Buchsbaum Isabel Y. , Khattak Shahryar , Fabien Guimiot , Binder Elisabeth , Elmslie Frances , Guerrini Renzo , Baffet Alexandre D. , Sieber Stephan A. , Treutlein Barbara , Robertson Stephen P. , Cappello Silvia
Published: November 2021

Basal progenitors (BPs), including intermediate progenitors and basal radial glia, are generated from apical radial glia and are enriched in gyrencephalic species like humans, contributing to neuronal expansion. Shortly after generation, BPs delaminate towards the subventricular zone, where they further proliferate before differentiation. Gene expression alterations involved in BP delamination and function in humans are poorly understood. Here, we study the role of LGALS3BP, so far known as a cancer biomarker, which is a secreted protein enriched in human neural progenitors (NPCs). We show that individuals with LGALS3BP de novo variants exhibit altered local gyrification, sulcal depth, surface area and thickness in their cortex. Additionally, using cerebral organoids, human fetal tissues and mice, we show that LGALS3BP regulates the position of NPCs. Single-cell RNA-sequencing and proteomics reveal that LGALS3BP-mediated mechanisms involve the extracellular matrix in NPCs’ anchoring and migration within the human brain. We propose that its temporal expression influences NPCs’ delamination, corticogenesis and gyrification extrinsically.
Bird population declines and species turnover are changing the acoustic properties of spring soundscapes
Authors: Morrison C. A. , Auniņš A. , Benkő Z. , Brotons L. , Chodkiewicz T. , Chylarecki P. , Escandell V. , Eskildsen D. P. , Gamero A. , Herrando S. , Jiguet F. , Kålås J. A. , Kamp J. , Klvaňová A. , Kmecl P. , Lehikoinen A. , Lindström Å. , Moshøj C. , Noble D. G. , Øien I. J. , Paquet J-Y. , Reif J. , Sattler T. , Seaman B. S. , Teufelbauer N. , Trautmann S. , van Turnhout C. A. M. , Vořišek P. , Butler S. J.
Published: November 2021

Natural sounds, and bird song in particular, play a key role in building and maintaining our connection with nature, but widespread declines in bird populations mean that the acoustic properties of natural soundscapes may be changing. Using data-driven reconstructions of soundscapes in lieu of historical recordings, here we quantify changes in soundscape characteristics at more than 200,000 sites across North America and Europe. We integrate citizen science bird monitoring data with recordings of individual species to reveal a pervasive loss of acoustic diversity and intensity of soundscapes across both continents over the past 25 years, driven by changes in species richness and abundance. These results suggest that one of the fundamental pathways through which humans engage with nature is in chronic decline, with potentially widespread implications for human health and well-being.
Distinct methane-dependent biogeochemical states in Arctic seafloor gas hydrate mounds
Authors: Klasek Scott A. , Hong Wei-Li , Torres Marta E. , Ross Stella , Hostetler Katelyn , Portnov Alexey , Gründger Friederike , Colwell Frederick S.
Published: November 2021

Archaea mediating anaerobic methane oxidation are key in preventing methane produced in marine sediments from reaching the hydrosphere; however, a complete understanding of how microbial communities in natural settings respond to changes in the flux of methane remains largely uncharacterized. We investigate microbial communities in gas hydrate-bearing seafloor mounds at Storfjordrenna, offshore Svalbard in the high Arctic, where we identify distinct methane concentration profiles that include steady-state, recently-increasing subsurface diffusive flux, and active gas seepage. Populations of anaerobic methanotrophs and sulfate-reducing bacteria were highest at the seep site, while decreased community diversity was associated with a recent increase in methane influx. Despite high methane fluxes and methanotroph doubling times estimated at 5–9 months, microbial community responses were largely synchronous with the advancement of methane into shallower sediment horizons. Together, these provide a framework for interpreting subseafloor microbial responses to methane escape in a warming Arctic Ocean.
Subglacial discharge controls seasonal variations in the thermal structure of a glacial lake in Patagonia
Authors: Sugiyama Shin , Minowa Masahiro , Fukamachi Yasushi , Hata Shuntaro , Yamamoto Yoshihiro , Sauter Tobias , Schneider Christoph , Schaefer Marius
Published: November 2021

Water temperature in glacial lakes affects underwater melting and calving of glaciers terminating in lakes. Despite its importance, seasonal lake temperature variations are poorly understood because taking long-term measurements near the front of calving glaciers is challenging. To investigate the thermal structure and its seasonal variations, we performed year-around temperature and current measurement at depths of 58–392 m in Lago Grey, a 410-m-deep glacial lake in Patagonia. The measurement revealed critical impacts of subglacial discharge on the lake thermal condition. Water below a depth of ~100 m showed the coldest temperature in mid-summer, under the influence of glacial discharge, whereas temperature in the upper layer followed a seasonal variation of air temperature. The boundary of the lower and upper layers was controlled by the depth of a sill which blocks outflow of dense and cold glacial meltwater. Our data implies that subglacial discharge and bathymetry dictate mass loss and the retreat of lake-terminating glaciers. The cold lakewater hinders underwater melting and facilitates formation of a floating terminus.