bluuebunny/crossref_metadata_2025 huggingface dataset:
On-line targeted metabolomics for real-time monitoring of relevant compounds in fermentation processes
Authors: Garcia Joan Cortada , Haggarty Jennifer , Weidt Stefan , Daly Ronan , Arnold Alison , Burgess Karl
Published: May 2023

Fermentation monitoring is a powerful tool for bioprocess development
and optimisation. On-line metabolomics is a technology that is starting
to gain attention as a bioprocess monitoring tool, allowing the direct
measurement of many compounds in the fermentation broth at a very high
time resolution. In this work, targeted on-line metabolomics was used to
monitor 40 metabolites of interest during three Escherichia coli
succinate production fermentation experiments every 5 minutes with a
triple quadrupole mass spectrometer. This allowed capturing high time
resolution biological data that can provide critical information for
process optimisation. For 9 of these metabolites, simple univariate
regression models were used to model compound concentration from their
on-line mass spectrometry peak area. These on-line metabolomics
univariate models performed comparably to vibrational spectroscopy
multivariate PLS regressions models reported in the literature, which
typically are much more complex and time consuming to build. In
conclusion, this work shows how on-line metabolomics can be used to
directly monitor many bioprocess compounds of interest and obtain rich
biological and bioprocess data.
Cultural identity and sustainable cultural tourism in the context of local and global
Authors:   University of National and World Economy, Bulgaria, Parusheva Tanya
Published: May 2023

The scientific article aims to explore the relationship between cultural identity and sustainable cultural tourism in the context of local and global. Important elements of cultural identity and heritage have been studied. Emphasis is placed on the attempts of local communities to develop their tangible and intangible cultural assets. The connection between cultural identity, sustainable cultural tourism and globalization is considered. The importance of the authentic characteristics of the destinations and the unique elements of their cultural identity is emphasized. The author defends the thesis that sustainable cultural tourism is the best model for local tourism development in a global context.
Wine tourism in the area of the Varna Black Sea coast: opportunities for sustainable development
Authors:   University of Economics- Varna, Bulgaria, Lukanova Georgina
Published: May 2023

The aim of the following paper is to underline the role and importance of wine tourism as an alternative form for the sustainable tourism development in the Varna Black Sea tourist region. The first part of the report examines the main characteristics of wine tourism as an alternative form of tourism. The second part of the report is dedicated to the analysis of the resource potential of the Varna Black Sea tourist region for the development of wine tourism. The largest wine cellars are presented, with a focus on the conditions for tourist visits. In the end of this paper the possibilities for development of wine tourism in the researched area are summarized.
The European Green Pact and the wine tourism prospects in Bulgaria
Authors:   University of National and World Economy, Bulgaria, Rangelov Christian
Published: May 2023

This scientific article aims to analyze the opportunities for sustainable development of wine tourism in the context of the European Green Pact. The Green Deal and the goals it sets for the countries of the community are discussed. An analysis of the wine production in Bulgaria and the European Union (EU) has been made. A definition of sustainable tourism according to the leading ecological norms has been derived. The goals set are related to the new conditions that wine tourism will face. The expectations from the implementation of the European Green Pact are discussed. Emphasis is placed on the relationship between wine producers and wine tourism. Examples of sustainable wine tourism in a modern, efficient and competitive economy are given. Based on the analysis, the conclusions are presented.
Regression Analysis Video Tutorials to Improve College Students' Data Analysis Skills
Authors: Noor Widya Noviana , Wulansari Widi
Published: May 2023

To improve the quality of education in terms of data analysis, a learning innovation is needed. Moreover, in learning statistics, the requirements for complicated calculations require an innovative product that can overcome these problems. The purpose of this research is to develop video tutorials on regression analysis to improve students' data analysis skills. The type of research that has been carried out uses RnD (Research and Development) research with a quantitative approach. The subjects of this study were students in two university as the site for the limited trial, and two university as the site for the large group trial. The analysis uses 2 designs: a pretest-posttest group design and a posttest-only design with a nonequivalent group. The results of this study indicate that video tutorials are suitable for students in carrying out simple linear regression analysis, and this research implies that students who use video tutorials in carrying out simple linear regression analysis have better skills than those who do not. Thus it can be concluded that video tutorials on regression analysis are able to improve students' data analysis skills.
Video Pembelajaran Geografi SMA Berbasis Kearifan Lokal untuk Meningkatkan High Order Thinking Skills (HOTS)
Authors: Astuti Indri , Darini  , Afandi
Published: May 2023

Kurangnya kemampuan siswa dalam keterampilan berpikir tingkat tinggi, mengaitkan kearifan lokal dalam pembelajaran serta kurangnya penggunaan media oleh guru berpengrauh terhadap proses dan hasil belajar. Penelitian ini bertujuan untuk mendeskripsikan desain pengembangan, profil dan mengetahui efektivitas video pembelajaran. Jenis penelitian ini adalah penelitian Research and Development (R&D) dengan model ADDIE. Subjek validasi adalah lima ahli media, lima ahli desain, dan empat ahli materi serta 26 siswa. Subjek uji efektivitas berjumlah 30 siswa dan subjek validasi soal 30 siswa. Data yang diperoleh adalah data kualitatif dan kuantitatif. Data dikumpulkan dengan metode observasi, dokumentasi, angket dan tes. Analisis data menggunakan deskriptif kuantitatif, deskritif kualitatif dan statistik inferensial uji t serta uji effect size. Hasil penelitian adalah (1) deskprisi desain video pembelajaran. (2) profil video pembelajaran (3) evektifitas video pembelajaran melalui uji effect size, hasilnya 2,614 dengan kategori “strong effect”. Dengan demikikan, video pembelajaran geografi SMA berbasis kearfian lokal dapat diterapkan sebagai media pembelajaran untuk meningkatkan High Order Thinking Skills.
Modul Digital Matematika Berbasis Metakognitif untuk Meningkatkan Kemampuan Pemecahan Masalah Siswa SD
Authors: Rahmaniah Wilda Alfiatul , Zainuddin Almuntaqo
Published: May 2023

Penelitian ini bertujuan untuk mengembangkan modul matematika berbasis metakognitif sebagai solusi dalam meningkatkan kemampuan pemecahan masalah siswa khusunya pada pembelajaran operasi hitung bilangan cacah kelas II SD. Penelitian ini dilaksanakan di SD Negeri 2 Drono, dengan metode penelitian dan pengembangan (Research and Development) menggunakan model ADDIE . Pengumpulan data diperoleh melalui wawancara, observasi, dan angket. Hasil validasi ahli media diperoleh  presentase sebesar 80% dengan kriteria sangat layak. Pada validasi ahli materi diperoleh presentase sebesar 92% dengan kriteria sangat layak. Sehingga berdasarkan uji validasi ahli media dan ahli materi modul dikatakan valid dan siap untuk ujicoba lapangan. Berdasarkan hasil penelitian di sekolah melalui ahli praktisi diperoleh presentase 93% dengan kriteria sangat layak. Berdasarkan penelitian tersebut dapat disimpulkan bahwa pengembangan modul digital matematika berbasis metakognitif, modul layak dan siap untuk digunakan sabagai bahan ajar.
Salafi Online: Dakwah Salafi Pada Akun Instagram @dakwah_tauhid
Authors: Pramana M Agung
Published: May 2023

Tulisan ini menganalisis aktivitas dakwah Salafi online di Indonesia yaitu pada akun Instagram @dakwah_tauhid. Salafi adalah sebuah gerakan pemurnian agama Islam yang mengajak masyarakat Muslim untuk kembali kepada ajaran Alquran dan sunnah, serta para Salafush Shalih. Berbeda dengan masyarakat Muslim pada umumnya, kelompok Salafi cenderung memiliki pemahaman agama yang rigid dan kaku. Artikel ini menjawab pertanyaan utama yaitu bagaimana aktivitas dakwah Salafi online di Indonesia? Sedangkan pertanyaan lanjutan yang akan penulis eksplorasi yaitu bagaimana pergeseran penyebaran paham Salafi dari era Orde Baru, Reformasi, dan kontemporer? Untuk menjawab pertanyaan-pertanyaan tersebut, penulis menggunakan metode netnografi melalui akun Instagram @dakwah_tauhid. Kemudian penulis menganalisisnya dengan literatur-literatur sebelumnya yang relevan. Hasil penelitian menunjukkan bahwa terjadi pergeseran penyebaran paham Salafi dari era Orde Baru, Reformasi dan saat ini. Melalui akun Instagram @dakwah_tauhid, penelitian ini menunjukkan bahwa penyebaran paham Salafi telah mengarah pada cara-cara digital yang sesuai dengan perkembangan teknologi, informatika, dan komunikasi. Mereka secara masif menggunakan Instagram untuk menguatkan posisinya sebagai gerakan Islam puritan dan mendapatkan penerimaan yang positif dari pengikutnya.
An Extraordinary Duet: Integration of PjBL and STEM to Promote Student’s Motivation, Scientific Literacy Skills, and Students Learning Outcomes
Authors: Nurhayati B  , Jamaluddin Fathul J. , Daud Firdaus , Saenab Sitti , Hadis Abdul , Hadis Nurul I. Romadhana , Remiza
Published: May 2023

This study aimed to investigate the effect of the STEM-integrated PjBL learning model on students’ motivation, scientific literacy skills, and learning achievement. The study used a non-equivalent control group design with a population of eleventh-grade high school Islam Athirah II Makassar students. Science Class 1 and Science Class 2 were included in the sample. The research instruments consisted of a learning motivation questionnaire, a Test of Scientific Literacy Skill (TOSLS), and an achievement test consisting of 20 multiple-choice questions. The Independent Sample t-test was used to assess the research data. The results indicated that the STEM-integrated PjBL learning model had a significant effect on students’ learning motivation, scientific literacy skills, and learning outcomes, with a significance value of 0.00 (<0.05). According to these findings, the STEM-integrated PjBL learning model can be utilized to increase students’ motivation, scientific literacy skills, and learning outcomes.
Pemberdayaan Masyarakat Kenagarian Silokek Kabupaten Sijunjung Dalam Mengembangkan Potensi Olahraga tubing
Authors: Khairuddin  , Handayani Sri Gusti , Sepriadiansyah
Published: May 2023

Permasalahan dalam kegiatan ini adalah belum diketahui data tentang pengelolaan, sarana dan prasarana wisata, minimnya tenaga pemandu/skiper untuk kegiatan olahraga wisata Tubing di Nagari Muaro Silokek Kabupaten Sijunjung. Dan beum adanya spot olahraga wisata yang bisa dikembangkan oleh masyarakat di Kenagarian Silokek. Dengan adanya kendala tersebut tentunya akan menghambat berkembangnya potesnsi olaraga wisata di Kabupaten Sijunjung. Sasaran kegiatan ini adalah masyarakat di Kenagarian Silokek, Kabupaten Sijunjung.. Hasil dari kegiatan ini adalah meningkatnya pemahaman dan keterampilan masyarakat di Kenagarian Solikek Kabupaten Sijunjung dalam mengelola, mengembangkan, olajhraga wisata Tubing di Kenagarian Silokek. Metode yang akan digunakan dalam kegiatan pengabdian ini adalah melalui pelatihan langsung secara teori dan praktek.
Mein Praktikum - bewerben, einsteigen, aufsteigen
Authors: Bloss Michael
Published: May 2023

Dieses Buch zeigt auf einfache Weise, wie Sie das Maximum aus Ihrem Praktikum herausholen. Der Autor orientiert sich dafür an den sechs Phasen eines Praktikums: Entscheidungs-, Bewerbungs-, Start- und Orientierungsphase, Alltags- und Abschiedsphase sowie letztlich an der Frage der Rückkehr. Alle wichtigen Aspekte werden verständlich und mit vielen Beispielen und Checklisten erläutert. Zudem helfen digitale Übungsfragen bei der Vorbereitung zu Bewerbungsgesprächen und dem eigentlichen Praktikum. Abgerundet wird das Buch durch sieben spannende Kurz-Interviews mit der Personalabteilung, mit einer Führungskraft und mit den Erfahrungen von anderen Praktikanten. Ein unverzichtbarer Ratgeber für alle, die ihr Praktikum als Karrieresprungbrett nutzen wollen.
CoMFA INVESTIGATION FOR A SERIES OF PRENYL-ALKYLATED BIS-1,2,4-TRIAZOLES
Authors: Korol N. , Holovko-Kamoshenkova O. , Slivka M. , Lendel V.
Published: May 2023

Predictive strategies and approaches are now widely used by scientists in molecular biology and chemistry for the synthetic design of potentially active compounds.

Comparative molecular field analysis (CoMFA) is a technique for determining three-dimensional quantitative structure-activity relationships (3D QSAR). According to the methodology, it is necessary to choose the bioactive conformation of each studied compound, and all structures are superimposed. According to the results, mapping was carried out and thus the steric and electrostatic fields of these molecules are calculated, which makes possible to evaluate further favorable ways for functionalization of the tested substances.

The 1,2,4-triazole fragment is a proven valuable component in medicine, as it is part of a number of medicines, and in recent works we have also proven their high biological effect and predicted ways of using condensed and functional derivatives.

In the framework, we conducted the synthesis of prenyl-alkylated bis-1,2,4-triazoles and CoMFA studies with the aim of evaluating directions for further synthetic design and functionalization of the target compounds to increase their valuable bioproperties.

Keywords: bis-1,2,4-triazole; alkylation; CoMFA; bioactivity.
Habilidades Blandas del Arquitecto en formación en la Cuarta Revolución Industrial
Authors: Linares Bermúdez Maria Auxiliadora
Published: May 2023

El presente artículo de reflexión tuvo como objetivo comprender la importancia de las habilidades blandas del arquitecto en formación en el escenario de la cuarta revolución industrial, al ser entendidas como un elenco de rasgos personales que permiten a los seres humanos relacionarse consigo mismos y con otros. Metodológicamente, se trabajó con una revisión documental de autores como Schwab (2016), la NSSA (2019), Gasca & Machuca (2019), Mora (2019), Alfaro (2020), Llanes & Lorenzo (2021), entre otros, a partir de los cuales se realizó un análisis hermenéutico de las habilidades blandas demandadas en los arquitectos en formación en el contexto actual y por venir. Se evidenció la relevancia de estas habilidades de cara a afrontar los desafíos laborales en un escenario mediado e impactado por la  tecnología, así como la urgente necesidad de emprender actividades formativas a nivel universitario que permitan desarrollar en los arquitectos en formación competencias de liderazgo, trabajo en equipos, responsabilidad, gestión del tiempo y de las emociones, adaptabilidad a nuevas maneras de diseñar, comercialización y entrega de nuevos productos y servicios, entre otras de carácter actitudinal. Estas habilidades, aunadas a destrezas comunicativas tanto a nivel presencial como a nivel tecnológico, posibiliten impulsar el desempeño laboral de los futuros profesionales de la arquitectura en el contexto altamente tecnologizado de la cuarta revolución industrial.
Diseño de sistemas de empaque y embalaje sostenibles para dos conjuntos de piezas cerámicas
Authors: Rodríguez López Karla Indira , Clemente Guerrero Dulce María , Rosas González Armando
Published: May 2023

Los envases, empaques y embalajes son elementos que sirven para identificar y proteger a los productos. Los objetos cerámicos y de alfarería son piezas ornamentales que se caracterizan por su fragilidad y por ser difíciles de transportar. Usar sistemas de empaque y embalaje (SEE) deficientes durante el almacenamiento, transporte y manejo de los productos cerámicos y de alfarería provoca, comúnmente, su rotura, rayadura o desportilladura. El estado de Oaxaca es uno de los territorios con mayor producción de cerámica y alfarería en México, tanto a nivel artesanal como industrial. No obstante, los productores improvisan el uso de SEE que no garantizan el arribo seguro de sus productos. En este artículo de investigación se desarrollaron SEE para un par de conjuntos de piezas cerámicas que produce una empresa de alfarería y cerámica oaxaqueña, la cual ha registrado de forma constante pérdidas significativas de productos debido a la ineficiencia de sus empaques y embalajes actuales. Para el desarrollo del proyecto se utilizó la metodología propuesta por Munari (2016), juntamente con aspectos concernientes a la ingeniería y diseño de empaques y embalajes, ecodiseño, ergonomía, normativas nacionales y aplicaciones CAD. Los SEE conceptualizados se caracterizan por poseer materiales amigables con el medio ambiente, sus características formales y funcionales permitirán disminuir su tiempo de armado, incrementar la protección de las piezas, aumentar el número de productos que podrán transportarse y brindar un segundo uso a algunos elementos que los conforman. De esta forma, se conceptualizaron SEE que podrían representar una alternativa más eficiente y sostenible para el almacenamiento, transporte y manejo de los productos cerámicos y de alfarería, superando las deficiencias de los empaques y embalajes que actualmente se emplean.
Citizen Participation: A Matter of Competency
Authors: Souad Sassi Boudemagh , Rafika Korti
Published: May 2023

Citizens are social actors willing to give their time and energy to participate in collective projects, in order to live better in their built environment. Thus, the inhabitant is not only apprehended as a figure of belonging to a place, but he is perceived as being able to act on his environment, to be in connection with it. He is the one who invents his living environment and, beyond, transforms the city in the same way as the other actors. Individuals must acquire skills to become effective participatory citizens and live together in peace and on an equal footing in democratic societies. The recent work in the social sciences, which deals with "scholarly knowledge" and "ordinary knowledge", makes it possible to conclude on this notion of skills and to make the link with the question of the participation of the inhabitants. The "scholarly knowledge" is classified as scientific academic and professional knowledge, opposing knowledges qualified as profane or ordinary, that is to say, shared "by all or part of the social world". From a systemic point of view, the process of participation would be the meeting of these academic knowledge and lay knowledge. The purpose of this article is to understand what types of skills the resident uses, as a resource person, a living force, to engage in the process of participation.
The Influence of the African Religious and Cultural Context and Its Impact on Lutheranism: The Case of Greater Sekhukhune District Municipality
Authors: Lebaka Morakeng Edward Kenneth
Published: May 2023

In Greater Sekhukhune District Municipality, traditional religion has played a significant role in transforming Christianity by confronting it with the decisive issue of indigenization. The purpose of this study was, therefore, to examine the inter-religious relations among Christianity and African Traditional Religion (ATR), and to explore how African religious and cultural values have impacted on Christian – ATR relations within the municipality, and how the latter has, also, been affected by the former. The primary research question raised in this study is: what is the relevance of indigenous people’s music in the existing (Lutheran) liturgy? The study employed an intercultural theological approach to Science and Religion, and the analysis is based on acculturation and the principle of elimination by substitution. The study also utilized a triangulated and contextual approach, and data was collected through observations, face-to-face interviews and video recordings of rehearsals and performances during church services and other related events. Secondary sources included published books and Journal articles. The investigation has revealed that the integration of spiritual folk songs (choruses), traditional musical instruments, handclapping, and dancing into liturgical church service of almost all Evangelical Lutheran churches found in Greater Sekhukhune District Municipality, has not compromised the essence of Lutheran tradition. It has rather encouraged maximum, active and unimpeded participation in liturgical church service and/or Congregational singing. Indications from the investigation have also shown that the dimensions of rhythm play an important role to contextualize and Africanize the existing (Lutheran) liturgy, in order to make the missionary qualities of worship an integral part of mission work. During the study, it was also observed that musical creativity and musicality in the visited churches embrace other elements such as the capacity for becoming absorbed emotionally in music and the ability to enter into an intimate relation with it, so that the whole organization of the soul is affected. It was concluded that it is indeed of great significance that indigenous people’s music should be regarded as a matter of relevance and ultimately becomes a vessel which carries the full meaning of the Gospel.
Portraits of Women Founders and Leaders in the North of Portugal: Do Academic Qualifications Matter in the Cultural Patterns of Family Firms?
Authors: Marques Ana Paula
Published: May 2023

This paper aims to discuss continuities and ruptures carried out by women in leadership in family firms (FFs). Despite female underrepresentation on top positions in firms broadly speaking, our findings gathered from the project “Roadmap for Portuguese Family Businesses” (NORTE-02-0853-FEDER-000018) reveal an ongoing transformation regarding intergenerational management succession in family firms. In fact, while it is recognizable that micro, meso and macro-structural gender barriers remain, family businesses have been the scene of intergenerational changes with a notable presence of women in management and corporate responsibility careers. To what extent have female founders and successors expressed significant changes in the cultural patterns of family businesses, especially when they have high academic qualifications and professional experience? To answer this research question, nine in-depth, semi-structured interviews were conducted with business women/ managers of family businesses regarding their career experiences compared with those of male counterparts. This paper finds that the “masculinist” perspective is shifting due to the crucial role of the qualifications and professional competence of family firms’ female founders and leaders. Likewise, the increase in the academic level of women in today's society is one of the factors that is at the root of the emergence of shifting in the cultural patterns of family businesses with impact in the intergenerational succession. (JEL: L2)
About the Discourse of the Necessity of Military Intervention in Brazil for the "Restoration of Order in the Country": Analytical Notes
Authors: Baronas Roberto , Bonani Tamires
Published: May 2023

In this work, based on the analysis of the French orientation discourse, we aim to reflect on a discourse that is becoming increasingly common in Brazil: the request for the Armed Forces to take control of the country by force. Although a recent past full of suffering, death and torture stamped the pages of the history books when telling about the Military Coup of 1964, research indicates the support of more than 40% of the population for a supposed military intervention in Brazil in 2018. In a quick survey of major newspapers in the country and in social networks, we noted that often some statements are associated with the demand for seizure of power, such as: "We are going to sanitize the country", "establish order", "in the name of God and the family, Brazil will be a serious country". Such relations between this "semantic universe" makes us question whether there is a discursive "order" that governs and sustains this need for military intervention in Brazil. Therefore, we will use a theoretical-discursive approach based on the concepts of Alice Krieg-Planque (2016), Dominique Maingueneau (2014) and Marie-Anne Paveau (2015), more specifically of small phrases and discursive virtue, respectively. The latter guides us in the sense of answering a question that the author herself asks: "Will there be good statements in the moral sense of the term? If so, what then is a statement capable of receiving a judgment of moral value? And how does moral value manifest itself linguistically?" (p. 24). This is because, for her, this notion "functions at the core of an ethics of values and supposes an intersubjective negotiation within a given group or given society" (p. 26). For the constitution of our corpus, will be analyzed especially statements published in newspapers and magazines of great circulation in the country.
The impact of work-related technology and boundary management on work-family conflict and enrichment during COVID-19
Authors: Feery Karen , Conway Edel
Published: May 2023

Technology has become a ubiquitous force in modern life, leading to the blurring of work-life boundaries. The recent global pandemic brought this to the fore, particularly in the context of academia, where the blurring of boundaries were already apparent. This study explores whether and how information communication technology (ICT) blurred boundaries and impacted work-family conflict (WFC) and work-family enrichment (WFE) during the COVID-19 pandemic. This examination is critical to optimise the value that ICTs may provide for the well-being of academics and their families. Drawing on semi-structured interviews, data was collected from 14 academics with children. Findings indicated that ICT triggered various stressors leading to WFC, while simultaneously improving participants’ availability leading to WFE. Managing boundaries was complex and depended on preferences and resources to enact these preferences. The findings highlight the paradoxical consequences of ICT, raising questions about increasing complexity in academic work and the need for more sustainable flexible work models.
O działaniach defensywnych w okresie budowy struktur państwowych Polski Odrodzonej
Authors:   Uniwersytet Humanistyczno-Przyrodniczy im. Jana Długosza w Częstochowie, Ćwięk Henryk
Published: May 2023

Polish counterintelligence was operating under difficult circumstances. Relatively small personnel handled the head office of the Second Department of General Staff and its field branches. The diversity of tasks, great workload, limited possibilities of using transport and communication did not stimulate work efficiency among the employees. However, the rather uniform policies of particular governments was a factor that facilitated the activity of counterintelligence. Taking into consideration the positive and negative phenomen accompanying the operation of defensive organs, it needs to be stated that they performed their duties well and used their resources to the fullest.
Służba Polaków w lotnictwie Floty Czarnomorskiej Imperium Rosyjskiego w latach I wojny światowej
Authors:   Uniwersytet Pedagogiczny w Krakowie, Herma Marek
Published: May 2023

During the First World War, an elite group of 112 pilots from the Russian Empire’s Black Sea fleet, who remained in service in the second half of 1917, included five officers of Polish nationality: second lieutenant commander Jan Stachowski, navy captain Wiktoryn Kaczyński, navy captain Wacław Iwaszkiewicz, naval lieutenant Eugeniusz Pławski, and second lieutenant Władysław Misiński. As shown in this article, they made a significant contribution to the development of a new type of naval force by performing command functions, training the aviation cadres of the fleet, and participating in combat operations in the Black Sea theater of military operations from 1914 to 1917. The policy of breaking up the pre-revolutionary structures, the regular armed forces of the Empire, and the anarchy spreading among the sailors prompted naval pilots of Polish nationality to end their service in the Russian Navy. After Poland regained its independence, they enlisted in the Polish Army, taking an active part in the fight for the borders of the reborn Republic of Poland. Thanks to their excellent training and combat experience from the Great War, they made a significant contribution to the newly formed Polish military aviation, which played an important role in the war with Bolshevik Russia. After the end of the fight for the borders of the Second Republic, they continued work to expand the Polish air force – including naval aviation – and helped organize a training system for air personnel. Keywords: naval aviation, aviation of the Black Sea fleet, Russian Black Sea fleet, World War I, navy of the Russian Empire, officer corps of the Russian navy.
Flota pancerników drednotowych Austro-Węgier
Authors:   Uniwersytet Pedagogiczny w Krakowie, Jastrzębski Jarosław
Published: May 2023

In the relatively long history of the dreadnought battleships 1905–2006, the Austro-Hungarian Navy had its short but significant episode. Between 1912 and 1915, it managed to introduce into service 4 ships of this class, extremely modern for their time, which in addition represented the fourth generation of dreadnoughts with their main weapons. They were Viribus Unitis, Tegetthoff, Prinz Eugen and Szent István. Another 4 battleships of this type have already been ordered, but their construction was interrupted by World War I. The collapse of the Habsburg Monarchy marked the end of the Austro-Hungarian fleet, and thus the loss of all ships. In the course of the aforementioned armed conflict, Austria-Hungary lost only one dreadnought, but the collapse of Austria-Hungary at its end forced the transfer of the remaining three to the State of Slovenes, Croats and Serbs, which happened on October 31, 1918.
Qiyas sebagai Konstitusi Keempat dalam Islam: Implementasi Qiyas dalam Konteks Siyasah
Authors: Pane Ramadhan Siddik , Siregar Sawaluddin
Published: May 2023

Abstract The problem faced by Muslims today in a constitutional context is a complex one. A revolutionary solution is needed to answer the problem and it is certainly not enough to use the classical Islamic legal methods. When viewed in the Islamic constitution, many of the problems that arise today are textually absent from the provisions of the law. Thus, to answer these problems requires a systematic methodology and legal formulation. In answering and formulating legal provisions in contemporary cases, it can be done by the qiyas method. This study aims to formulate the qiyas methodology as the fourth constitution in Islam to answer all problems of Muslims in the context of siyasah. Various things that are the object of research are in the fields of siyasah harbiyah, siyasah dusturiyah, and siyasah maliyah. The three siyasah in the national constitutional system are known as the state defense system, the state legislative system, and the state revenue and taxation system.   To facilitate this research, the author utilizes the theory of literature research with a qualitative research approach. Researchers first formulate one problem and then collect various literature models related to the theme. Then the researcher analyzes each of these literatures to formulate qiyas formulations in the context of siyasah. The main problem in this study is how the formulation of qiyas in formulating Islamic law and how to implement qiyas in the issue of siyasah. Therefore, the results of this study can be described as showing that the formulation of qiyas must meet four pillars, namely the initial case, the initial case law, the branch case, and the 'illat law between the two cases. Then qiyas can be implemented in answering problems in the field of siyasah harbiyah, siyasah dusturiyah, and siyasah maliyah Keywords: Constitution, Qiyas, Siyasah
HPI Perspective Child Abuse Analysis
Authors: Siregar Muhammad Ridho
Published: May 2023

This research is backgrounded by the crime of obscenity against minors who have not reached the age of 18 years, such as the case that occurred at Batu Rusa Beach, Tabuyung Village, Muara Batang Gadis District, Mandailing Natal Regency. The repeated obscenity of two of his stepsons, in this case, the prosecutor charged him with imprisonment for 11 years and a fine of Rp. 100,000,000, while the judge sentenced him to imprisonment for 13 years and a fine of Rp. 100,000,000. The formulation of the problem in this study is how the judges consider in imposing criminals in the decision of the Mandailing Natal District Court number 2 / Pid.Sus / 2021 / PN.Mdl, How is the review of Islamic Criminal Law against the decision of the Mandailing Natal District Court number 2 / Pid.Sus / 2021 / PN.Mdl. The purpose of this study is to find out the judge's consideration in imposing a criminal in the decision of the Mandailing Natal District Court number 2 / Pid.Sus / 2021 / PN.Mdl,  This research uses a descriptive qualitative method, namely research conducted to find out and study intensively the background of circumstances, community conditions, interactions of individuals, groups, institutions, and social groups. The data collection techniques used in this study are interviews, and documentation. The results of the study stated that the judge's consideration in decision number 2/Pid.Sus/2021/PN.Mdl was appropriate according to juridical and non-juridical considerations. The judge's consideration in decision number 2/Pid.Sus/2021/PN.Mdl according to the Islamic Criminal Law, the punishment that has been determined by the panel of judges is in accordance with the Islamic Criminal Law, namely ta'zir which in this case is the one with regard to independence in the form of imprisonment for 13 (thirteen) years and a fine of Rp. 100,000,000.00 (one hundred million rupiah) provided that if the fine is not paid, it will be replaced by imprisonment for 6 (six) months.
Sanction For Liquor Providers From The Perspective Of Islamic Criminal Lw
Authors: Isliani Yenni
Published: May 2023

Sanctions are penalties given to a person who violates laws or rules aimed at providing a deterrent effect and reducing criminal acts. The formulation of the problem from this study is how are the sanctions for liquor providers according to Perda No.07 of 2015 in Padang Lawas Regency? and what is the review of Islamic criminal law against the sanctions of liquor providers according to Perda No.07 of 2015?. The purpose of this researcher is to find out the sanctions for liquor providers in the Padang Lawas bylaws and on Islamic criminal law. The theory used in this study is a theory related to the legal sanctions of liquor providers in Islamic criminal law and the legal sanctions of liquor providers in the Padang Lawas Regional Regulation. Furthermore, the type of research used is library research, using a normative juridical approach.The results of the research obtained are that the sanctions given against liquor providers in Article 22 paragraph 1 of Padang Lawas Regional Regulation No.07 of 2015 are a three-month penalty or a fine of Rp.50,000,000 (fifty million rupiah). In Islamic crimes, the sanction has been imposed with the punishment of hadd, namely dera (whipping) as much as 80 (eighty) times, forty times dera (whipping) is a decree of Allah Swt and forty times more is a punishment of ulil amri. The sanctions in Article 22 paragraph 1 of the Padang Lawas Regional Regulation are very light compared to the sanctions given in Islamic criminal law.
IMPLEMENTATION OF THE PADANGSIDIMPUAN CITY REGULATION NO. 4 OF 2010 ARTICLE 33 CONCERNING MARKET SERVICE FEES IN PADANGSIDIMPUAN
Authors: Tobing Dini Pebriani , Aziz Siregar Fatahuddin
Published: May 2023

Implementation of Padangsidimpuan City Regulation Number 4 of 2010 Article 33 concerning Market Service Fees in Padangsidimpuan. To obtain the data needed, the research was carried out by means of observation, interviews and documentation. The data sources used are the Head of the Market Management Division, Billing Officers and Traders as Mandatory Retribution. And the data taken as supporting primary data, including official documents, legal books, journals and articles related to this research.        Based on the results of the research that the implementation of the Padangsidimpuan City Regional Regulation No. 4 of 2010 Article 33 has not been effective in conducting field collections and is not in accordance with existing provisions. Among the causes of the ineffectiveness of Regional Regulation No. 4 of 2010 Article 33 concerning Market Service Retribution, namely socialization, human resources, lack of awareness of mandatory levies, the outbreak of covid 19 and inefficient supervision.
Factores de renuencia a la citología cervical en estudiantes de medicina
Authors: Gómez Carrera Lourdes , Valencia Rosano Ruth Ismari , Coronel Brizio Pedro Guillermo
Published: May 2023

Introducción: El cáncer cervicouterino (CaCu) ocupa la cuarta posición en incidencia (6.6%) y mortalidad (7.5%) de los diagnósticos de cáncer mundial. El tamizaje con citología cervical ha sido de gran beneficio en la detección oportuna de lesiones premalignas o malignas de bajo grado. Sin embargo, existen varios impedimentos para que las mujeres acudan a hacerse la prueba del Papanicolau. Objetivos: Identificar los factores por los cuales las estudiantes de la Licenciatura de Médico Cirujano (LMC) en la Universidad Veracruzana Campus Xalapa no acuden a la toma de citología cervical (CC). Material y métodos: Es una investigación descriptiva, de naturaleza cuantitativa. La recolección de datos se llevó a cabo en estudiantes de diferentes semestres de sexo femenino pertenecientes a la LMC de la Unidad de Ciencias de la Salud de la Universidad Veracruzana, Campus Xalapa, en la ciudad de Xalapa, Veracruz, México. La población total de alumnos de la facultad es de 787 y de éstos, 380 son mujeres, de las cuales participaron 69. Resultados: Sólo 51% de las alumnas encuestadas se había efectuado CC; una vez 33%, 2 veces el 6%, 3 el 6%, y 5 y 6 veces el 3%. Sobre los factores por los cuales el 49% de alumnas investigadas no se efectuó la prueba de CC se encuentra: falta de información 3%; motivos económicos 5%; por causa de incomodidad 5%; falta de tiempo 16%; no le dio importancia 14%; su médico no lo solicitó, y me siento bien de salud 18%. Conclusiones: La población de estudio no se realiza la prueba de citología cervical en tiempo y forma de acuerdo con las recomendaciones basadas en la NOM 014, Guías de Práctica Clínica, y la Asociación Americana contra el Cáncer.
Distributive Justice, Democracy and Growth
Authors: Khalifa Sherif
Published: May 2023

This paper argues that the effect of income inequality on economic growth depends on the level of democracy in a country and whether people believe that redistribution is an essential component of the democratic process. The paper uses the World Values Survey to focus on countries where the majority believe that taxing the rich and subsidizing the poor an essential component of democracy, and on countries where the majority believe that the rich do not buy elections in their country. Using the threshold estimation technique introduced by Hansen (1999), the analysis suggests the presence of a statistically significant threshold income inequality level, below which democracy does not have a statistically significant effect on growth, and above which an increase in the dose of democratization has a statistically significant negative effect on economic growth. The interpretation is that in countries where income inequality is high, and the majority believe that taxing the rich and subsidizing the poor is an essential component of democracy, a higher level of democratic governance allows people to support redistribution policies which can deter investment and economic growth.
Holding solution pH and composition consistently improve vase life of rose, lily and gerbera
Authors: Othman Yahia A. , A’saf Tala S. , Al-Ajlouni Malik G. , Hani Muayyad Bany , Hilaire Rolston St.
Published: May 2023

We assessed the influence of postharvest pulsing solutions pH and composition on cut flower quality of rose (Rosa hybrida cvs. Avalanche and Black Magic), gerbera (Gerbera jamesonii cv. Beaudine) and lily (Lilium × elegans cv. Fangio) under room (20±2 °C) and cold storage (4±1 °C) conditions. Cut flowers were placed in different acidic (pH, 3.5 - 4) or basic (pH, 7.0 - 7.5) preservative solutions containing water, sugar 5% (flower food), 100 mg/L silver nitrate (AgNO3 act as a bactericide), or a commercial product (2% sugar + bactericide and fungicide). Acidic solutions had higher or similar (never lower) vase life at both room and cold storage conditions and across species. In addition, vase life was 3-4 times longer in cold storage when compared to room conditions. Leaf chlorophyll concentrations for rose and lily were inconsistent or not significant across the species at both conditions (room and cold storage). The commercial preservative solution consistently and significantly had higher vase life than water for all tested cut flower species and under both room and cold storage environments. AgNO3 ranked second in terms of vase life enhancement. Overall, the use of only flower food (sugar) or bactericide (AgNO3) had a positive impact on vase life but only the combined use of a preservative substance (specifically at pH, 3.5 - 4.0) consistently guaranteed a high cut flower quality across flower species.
A Generalized Kirkwood Implicit Solvent for the Polarizable AMOEBA Protein Model
Authors: Corrigan Rae , Thiel Andrew , Lynn Jack , Casavant Thomas , Ren Pengyu , Ponder Jay , Schnieders Michael
Published: May 2023

Computational simulation of biomolecules can provide important insights into protein design, protein-ligand binding calculations, and ab initio biomolecular folding, among other applications. Accurate treatment of the solvent environment is essential in such applications, but use of explicit solvent can add considerable cost. Implicit treatment of solvent effects using a dielectric continuum model is an attractive alternative to explicit solvation since it is able to describe solvation effects without the inclusion of solvent degrees of freedom. Previously, we described the development and parameterization of implicit solvent models for small molecules. Here, we extend the parameterization of the generalized Kirkwood (GK) implicit solvent model for use with biomolecules described by the AMOEBA force field via the addition of interstitial space corrections to account for biomolecular geometry. These corrections include updating pairwise descreening scale factors to be element-specific and adding neck and tanh corrections to the calculation of effective radii. We then apply the AMOEBA/GK implicit solvent to a set of nine proteins and achieve an average RMSD of 2.1 Å across 500 ns simulations. Overall, the continued development of implicit solvent models will help to facilitate simulation of arbitrary biomolecules on biologically relevant timescales.
A chemoselective polarity-mismatched photocatalytic C(sp3)–C(sp2) cross-coupling enabled by synergistic boron activation
Authors: Brals Jeremy , McGuire Thomas , Watson Allan
Published: May 2023

We report the development of a C(sp3)–C(sp2) coupling reaction using styrene boronic acids and redox-active esters under photoredox catalysis. The reaction proceeds through an unusual polarity-mismatched radical addition mechanism that is or-thogonal to established processes. Synergistic activation of the radical precursor and organoboron are critical mechanistic events. Activation of an N-hydroxyphthalimide (NHPI) ester by coordination to boron enables electron transfer, with decom-position leading to a nucleofuge rebound, activating the organoboron to radical addition. The unique mechanism enables chemoselective coupling of styrene boronic acids in the presence of other alkene radical acceptors. The scope and limitations of the reaction, and a detailed mechanistic investigation are presented.
Exploring the binding pathway of novel non-peptidomimetic plasmepsin V inhibitors
Authors: Bobrovs Raitis , Drunka Laura , Kaņepe Iveta , Jirgensons Aigars , Caflisch Amedeo , Salvalaglio Matteo , Jaudzems Kristaps
Published: May 2023

Predicting the interaction modes and binding affinities of virtual compound libraries is of great interest in drug development. It reduces the cost and time of lead compound identification and selection. Here we apply path-based metadynamics simulations to characterise the binding of potential inhibitors to the Plasmodium falciparum aspartic protease plasmepsin V (plm V), a validated antimalarial drug target that has a highly mobile binding site. The potential plm V binders were identified in a high throughput virtual screening (HTVS) campaign and were experimentally verified in a fluorescence resonance energy transfer (FRET) assay. Our simulations allowed us to estimate compound binding energies and revealed putative transition states along binding/unbinding pathways in atomistic resolution. We believe that the method described allows the prioritisation of compounds for synthesis and enables rational structure-based drug design for targets that undergo considerable conformational changes upon inhibitor binding.
Engineering Lung-inspired Flow Field Geometries for Electrochemical Flow Cells with Stereolithography 3D Printing
Authors: Muñoz-Perales Vanesa , van der Heijden Maxime , García-Salaberri Pablo Ángel , Vera Coello Marcos , Forner-Cuenca Antoni
Published: May 2023

Electrochemical flow reactors are increasingly relevant platforms in emerging sustainable energy conversion and storage technologies. As a prominent example, redox flow batteries, a well-suited technology for large energy storage if the costs can be significantly reduced, leverages electrochemical reactors as power converting units. Within the reactor, the flow field geometry determines the electrolyte pumping power required, mass transport rates, and overall cell performance. However, current designs are inspired on fuel cell technologies but have not been engineered for redox flow battery applications where liquid-phase electrochemistry is sustained. Here, we leverage stereolithography 3D printing to manufacture lung-inspired flow field geometries and compare their performance to conventional flow field designs. A versatile two-step process based on stereolithography 3D printing followed by a coating procedure to form a conductive structure is developed to manufacture lung-inspired flow field geometries. We employ a suite of fluid dynamics, electrochemical diagnostics and finite element simulations to correlate the flow field geometry with performance in symmetric flow cells. The lung-inspired structural pattern is demonstrated to homogenize the reactant distribution in the porous electrode and to improve the electrolyte accessibility to the electrode reaction area. In addition, the results reveal that these novel flow field geometries can outperform traditional interdigitated flow field designs, as these patterns exhibit a more favorable electrical and pumping power balance, achieving superior current densities at lower pressure loss. Although at its nascent stage, additive manufacturing offers a versatile design space for manufacturing engineered flow field geometries for advanced flow reactors in emerging electrochemical energy storage technologies.