bluuebunny/crossref_metadata_2025 huggingface dataset:
The effect of sclerotherapy and pre-pregnancy training with inositol and vitamin D3 on the size and number of cysts in women with infertility on the background of endometriosis
Authors: Kulik I. I. , Khmil S. V.
Published: February 2021

Annotation. Among gynecological diseases, external genital endometriosis leads to disorders of reproductive function and promotes the development of infertility. Currently, the search for less traumatic and more effective treatments for endometriosis continues. The aim of our study was to analyze the diameter of endometrioid cysts in women with infertility on the background of endometriosis before and after sclerotherapy using pre-pregnancy preparation of a complex vitamin preparation with inositol and vitamin D3. The study included 105 women aged 22 to 40 years with endometriosis-associated infertility. The presence of cysts was confirmed by ultrasound and bimanual examination. The drug FT 500 plus was prescribed in a dosage of 1 sachet – once a day from the 2nd or 3rd day of the cycle for 2 menstrual cycles (the cycle in which sclerotherapy was performed and the next cycle). Vitamin D3 “EuTilia D3” was prescribed in prophylactic doses of 2000 IU to women, or therapeutic (depending on the diagnosed or refuted diagnosis of vitamin D hypovitaminosis). The sclerotherapy procedure was performed by transvaginal puncture of the cyst and aspiration of its contents under the control of transvaginal ultrasound, introduction into the capsule of the cyst (without violating its integrity) 76% ethanol solution. It was found that women with endometriosis-associated infertility, who underwent pre-pregnancy preparation with a complex vitamin preparation with inositol and vitamin D3 after sclerotherapy, probably decreased the diameter of cysts in the right (5.85 times) and left (5.57 times) ovaries relative to data before sclerotherapy. When comparing the diameter of cysts in women who underwent pre-pregnancy preparation with a complex vitamin preparation with inositol and vitamin D3, depending on the type of surgery (sclerotherapy or cystectomy) found a probable decrease in the diameter of cysts after sclerotherapy in the right (82.89%) and left (82.05%) ovaries for such data after cystectomy. Therefore, sclerotherapy with pregravidar preparation with a complex vitamin preparation with inositol and vitamin D3 in women with endometriosis-associated infertility probably reduces the diameter of cysts relative to the experimental group without pregravidar preparation, as well as to the group with a history of cystectomy.
Features of pathogenetic mechanisms of the interaction of viruses and platelets in patients with immune thrombocytopenia (review of literature)
Authors: Dudnyk V. М. , Furman V. H. , Izuymets О. І. , Fedchishen А. P. , Sinchyck N. I. , Kutsak О. V.
Published: February 2021

Annotation. One of the urgent interdisciplinar problems of modern medicine is to study the mechanisms of development of virus-induced thrombocytopenia in patients. The aim is to sum up current knowledge of viruses and platelets interaction, how viruses affect platelet and modulate adaptive immune response. A systematic review of the articles in the Pub Med database was conducted between 2007 and 2020, using search terms: platelets, thrombocytopenia, viral infection. Current data on the study of the mechanisms of platelet interaction with different types of viruses in immune thrombocytopenia in children were analyzed. We studied activation of platelets by a viral infection and how the immune response works. We know that the immune response is a cyclic multistage process involving T-lymphocytes, B-lymphocytes, macrophages, cytokines, Nk-cells. Antiplatelet antibodies are increase platelet clearance from the blood. The combination of antibodies with platelets leads to phagocytosis. In patients with immune thrombocytopenia ІgG antibodies are produced against GP/ІІ b/ІІІ or GP/І b/ІХ glycoproteins located on the platelet surface. In this situation it is possible to produce antibodies of other subclasses of ІgG, also a complement of fixing Іg G, rarelyІg А to other glycoprotein, or to other complexes Іb ІХ, Іа/ІІа. Since megakaryocytes express glycoprotein ІІb/ІІІа, Ів as well as other platelet antigens, they become a target for autoantibodies. Viruses can interact directly with platelets and megakaryocytes. In addition, platelets can be activated by viral antigen-antibody complexes and B- lymphocytes can produce antiplatelet antibodies. All of these processes are activate platelets and lead to increased consumption and remove of platelets, this causes hemorrhagic manifestation in patients.
Possibilities of using the dermatoglyphic method to identify an unknown person (literature review)
Authors: Kozan N. M. , Gunas V. I. , Mishalov V. D. , Voloshynovich V. M. , Chadyk V. O.
Published: February 2021

Annotation. The dermatoglyphic method of research, having gone through more than a century of development and transformation, from the stage of application to the comparison of fingerprints and palms to the method of detecting susceptibility to certain diseases, has become an integral, time-tested method in medicine. However, its main field of application is still forensic medicine, in particular, forensic criminalistics and the identification of unknown persons. The emergence of a large number of works and new methods of obtaining and analyzing dermatoglyphic indicators requires a systematic review and analysis in order to organize new knowledge in this area. The analysis of literature sources indicates the rapid development and justification of the use of digital methods to obtain dermatoglyphs of fingers and toes, palms and feet and further processing of digital images, and the use of artificial neural networks to improve expertise to identify an unknown person.
Modern experience in conducting cerebral oximetry in neonatology: review
Authors: Vlasov A.О.
Published: February 2021

Annotation. Near-infrared spectroscopy (NIRS), non-invasive monitoring of tissue oxygenation in many organs, has potentially high diagnostic and prognostic value in critically ill patients. Aim – to analyze modern scientific data on cerebral oximetry by near infrared spectroscopy in neonatal practice. A selective review of literature science data on Internet databases: Pub Med, UpToDate, Medscape EU and Pediatrics was carried out in retrospect. It has been established that understanding neonatal brain oxygenation may be of great clinical importance, since most neonatal pathology is associated with the brain. Vital monitoring provides important information about the infant's health, but does not offer direct information about oxygenation and brain perfusion. Monitoring brain oxygenation with NIRS, at least during the vulnerable transition period during the first 3 days after birth, provides the clinician with additional important information. It can guide clinical management to prevent brain injury and prevent unnecessary treatment, and can provide important information about the infant’s prognosis. Thus, NIRS is a promising non-invasive technology that provides continuous monitoring of neonatal oxygenation parameters. Significant limitations of the method are the difficulties in the clinical interpretation of regional oxygenation indices, the lack of large-scale studies to determine the normative values of regional oxygenation in newborns and to identify reliable prognostic indicators in violation of regional blood circulation. It is reasonable to expect the results of further research.
Systematization of expert approaches and problematic aspects of endodontic treatment quality assessment
Authors: Ratushny R. I. , Goncharuk-Khomyn M. Y. , Goderdzi N. , Bilinskiy O. Y. , Yurzhenko A. V.
Published: February 2021

Annotation. The lack of unified approach or algorithm for expert assessment of the endodontic treatment quality is the reason for registration of various prevalence indicators considering unsuccessful outcomes of pulpitis and periodontitis treatment, misinterpretation of the results and occurrence of problematic situations during the process of forensic dental assessment of iatrogenic dental status changes. Objective – to systematize and analyze the existing problematic aspects of expert assessment of the endodontic treatment quality and identify the most reasoned approaches for objectification of the endodontic interventions consequences. During provided research the calculation methodologies of indexes designed for assessing the consequences and results of endodontic treatment were studied. Additionally, a retrospective analysis of publications with described cases of complex and commission forensic medical and forensic dental examinations of dental care defects was provided, including endodontic treatment cases, cases with errors during endodontic interventions, and also relevant expert conclusions. Revealed that following index indicators could be used as the most expedient approaches for the objectification of endodontic interventions consequences: Peri-Apical Index (PAI), CBCT-PAI, Complex Periapical Index (COPI), Endodontically Treated Tooth Index (ETTI) and PESS (Periapical and Endodontic Status Scale); however, such indexes do not fully assess the quality of iatrogenic manipulations in the structure of the endodont. Thus, for a comprehensive assessment of the derived parameters associated with the dental treatment quality, and quality of endodontic interventions in particular, it is advisable to include in the forensic dental evaluation protocol the main domains, such as technical characteristics, level of patient satisfaction, level of service provided, additional components of the treatment process, and also additional ones, such as verification of experience, quantification of quality of life associated with changes in dental status, and stratification of the effectiveness of treatment.
PERAN GURU BK DENGAN LAYANAN INFORMASI DALAM MENGATASI KENAKALAN REMAJA BAGI SISWA KELAS X DI SMK TUNAS BANGSA
Authors: Jannah Syarifah Raudatul , Irhamni Gusti , Fauzi Zainal
Published: February 2021

Tujuan penelitian ini adalah untuk mengetahui layanan informasi yang berjalan saat ini dan untuk mengetahui peran layanan informasi dalam mengangani kenakalan remaja pada siswa kelas X SMK Tunas Bangsa. Desain penelitian  yang digunakan yaitu metode kualitatif.. Adapun jumlah sampel yang dibutuhkan dalam penelitian ini dengan lima orang siswa yaitu dengan meminta bantuan guru BK memilih beberapa siswa untuk mewawancara dan memberikan layanan informasi kepada lima orang siswa. Teknik analisis data yang digunakan yaitu wawancara, dan observasi. Dari hasil penelitian dapat ditari kesimpulan layanan informasi yang deiberikan untuk memberikan pemahaman kepada siswa tentang kenakalan remaja terutama tentang informasi yang dibutuhkan dan bisa membantu siswa dalam mengambil keputusan yang tepat dan ditemukannya bentuk kenalakan remaja yang ada di SMK Tunas Bangsa yaitu terlambat masuk sekolah, membolos, menyontek dan melanggar peratusan sekolah. Sarannya untuk guru bimingan konseling diharapkan lebih memberikan informasi sebnyak-banyaknya kepada siswa terkait dengan kenakalan remaja. ___________________________________________________________________ The purpose of this study was to determine information services currently running and to determine the role of information services in dealing with juvenile delinquency in class X SMK Tunas Bangsa students. The research design used is a qualitative method. The number of samples needed in this study with five students, namely by asking the guidance counselor to select several students to interview and provide information services to five students. The data analysis techniques used were interviews and observation. From the research results can be drawn the conclusion of the information services provided to provide understanding to students about juvenile delinquency, especially about the information needed and can help students in making the right decisions and finding forms of adolescent acquaintance in SMK Tunas Bangsa, namely late entry to school, truancy, cheating and violating school requirements. The suggestion for counseling guidance teachers is that it is hoped that they will provide as much information as possible to students regarding juvenile delinquency.
Hipertiroidismo
Authors: Cebola Joana Silva
Published: February 2021

As hormonas tiroideias influenciam quase todos os tecidos e órgãos do corpo humano, tendo um papel regulador em muitas funções fisiológicas. Apesar de múltiplas etiologias, as causas mais comuns de hipertiroidismo são a doença de Graves, o bócio multinodular tóxico e o adenoma tóxico. As manifestações clínicas do hipertiroidismo podem ir desde o estado assintomático até à tempestade tiroideia. Ao examinar o paciente com hipótese diagnóstica de hipertiroidismo deve ser realizada história clínica detalhada e exame objetivo que inclua avaliação da frequência cardíaca, pressão arterial, frequência respiratória, peso corporal e avaliação da glândula tiroideia. Os exames complementares de diagnóstico são selecionados em função da hipótese etiológica mais provável. Existem três opções no tratamento do hipertiroidismo: fármacos antitiroideus de síntese, ablação com iodo radioativo e cirurgia. É fundamental realizar um diagnóstico correto da etiologia responsável pelo hipertiroidismo, uma vez que a abordagem terapêutica depende da etiologia, mas também da idade do paciente, sintomas, existência de comorbilidades e preferências pessoais.
Campanha de vacinação para a gripe sazonal das pessoas em situação de sem-abrigo na cidade de Lisboa: uma descrição da experiência no Inverno 2015/2016
Authors:   Médico de Família, Martins Hugo Filipe Gonçalves , Venâncio Inês ,   Médico de Família, Pinto Bruno ,   Médico de Família, Fernandes Rui Neto ,   Médico de Família
Published: February 2021

Introdução: As pessoas em situação de sem-abrigo apresentam uma elevada probabilidade de desenvolverem doenças crónicas, o que as predispõe a complicações graves caso sejam infetadas com a gripe. Os objetivos deste estudo transversal foram identificar os critérios de elegibilidade e avaliar o impacto da vacinação contra influenza sazonal de pessoas em situação de sem-abrigo de Lisboa durante uma campanha vacinal. Material e métodos: A população alvo inclui pessoas em situação de sem-abrigo da região de Lisboa, no período compreendido entre 30 de novembro e 6 de dezembro de 2015. Todas as pessoas envolvidas deram o seu consentimento. Considerou-se significância estatística para valor de p inferior a 0,01. Resultados: Das 818 pessoas em situação de sem-abrigo em Lisboa, 382 (47%) foram vacinadas para influenza na época 2015/16. Das 269 pessoas sem-abrigo seguidas, 179 (67%) eram portadoras de uma ou mais doenças crónicas, 68 (25%) tinham antecedentes clínicos de infeções respiratórias, mas apenas 19 (28%) tiveram esse diagnóstico durante o Inverno de 2015-2016. Na sequência desta campanha de vacinação verificou-se uma redução significativa das infeções respiratórias (p<0,01; OR=15,0; IC 5,4-42,3). Das pessoas vacinadas apenas três tiveram infeção por influenza A (H1N1) sem registos de morte. Identificou-se que 194 (72% de 269) eram elegíveis para vacinação. Considerando que se encontram identificadas 818 pessoas em situação de sem-abrigo na cidade de Lisboa poder-se-á extrapolar que, destas, 591 seriam elegíveis. Admite-se que não foram vacinadas mais de metade das pessoas em situação de sem-abrigo elegíveis da região de Lisboa. Discussão e conclusões: É essencial reforçar as campanhas de vacinação contra a gripe na população em situação de sem-abrigo, procurando encontrar estratégias que facilitem o encaminhamento para consultas de vigilância nos cuidados de saúde primários, sobretudo se portadoras de doenças crónicas.
Avaliação do desempenho do teste rápido de urina no diagnóstico da infeção urinária em idade pediátrica
Authors: Cassamo Sofia , Ribeiro Marta , Carneiro Leonardo , Castanhinha Susana , Sá Gabriela Araújo e
Published: February 2021

Objetivos: As infeções do trato urinário (ITU) são das infeções bacterianas mais frequentes em pediatria. O exame bacteriológico da urina (EBU) é o teste referência para o diagnóstico de ITU. Sendo um exame moroso, a decisão de iniciar antibioterapia baseia-se na clínica e na urinálise (ASU). A suspeita de ITU na criança e adolescente poderá ser orientada pelo médico de família. O objetivo deste estudo foi avaliar a eficácia da ASU no diagnóstico precoce da ITU em idade pediátrica. Métodos: Efetuou-se um estudo observacional que incluiu doentes (0-18 anos) que recorreram à urgência pediátrica entre 01/01/2015 e 31/12/2016 e que realizaram colheita de urina para ASU e EBU. Foram analisados os resultados da ASU e comparados com os resultados do EBU. Atribuiu-se diagnóstico definitivo de ITU a todos os doentes com EBU positivo. Determinou-se a sensibilidade, especificidade, valor preditivo positivo (VPP), valor preditivo negativo (VPN) e odds ratio (OR) dos parâmetros nitritos e esterase leucocitária (EL) para o diagnóstico de ITU. Resultados: Das 3.400 amostras incluídas, 21,2% tiveram resultado bacteriológico positivo. O microrganismo mais frequente foi Escherichia coli. Os nitritos demonstraram sensibilidade de 28% e especificidade de 99% para o diagnóstico. A EL revelou sensibilidade de 90% e especificidade de 63%. Para o conjunto dos dois, a sensibilidade foi de 27% e a especificidade de 99%, com VPP 91% e VPN 83%. Para EL superior a 500 células/mcl verificou-se especificidade de 93%. No grupo etário 0-12 meses verifica-se um VPP 93% e VPN 82% para os dois em conjunto. Conclusões: Os resultados são concordantes com a literatura: a EL é sensível para o diagnóstico de ITU e os nitritos são específicos. O melhor indicador para exclusão de ITU foi a EL. Estes resultados poderão ser aplicados na consulta aberta de saúde infantil e juvenil ao nível dos cuidados de saúde primários.
Editorial: Green New Deal!? Wie rot ist das neue Grün?
Authors: Redaktion PROKLA
Published: February 2021

Editorial: Green New Deal!? Wie rot ist das neue Grün?
‫تكوين البيئة اللغوية فى الجامعة الإسلامية‬
Authors: Sabri Hatta
Published: February 2021

تطورت تعليم و تعلم اللغة العربية فى البلد إندونيسية تطويرة كبيرة. فتبدأ تعليم اللغة العربيةبالمدارس والجامعات منذ المستوى الروضة أو التعليم للأطفال حتى المستوى الجامعى. فى تطور وتنمية وترقيتها، تواجه تعلم و تعليم اللغة العربية إلى المشكلات المختلفة والمتنوعة. وتجرب المدرسين فى اختيار لحل تلك المشكلات. وأكثر فكرة تصدر إلى أهمية تكوين البيئة اللغوية ف تعليم اللغة العربية. فأكثر المدارس أي المعاهد تعلم العربية بتطبيق و تكوين البيئة العربية. وقليل من المستوى الجامعات التى تعلم فيها اللغة العربية. لذلك، هذه الكتابة تعطى أراء الكاتب عن السعي على تكوين البيئة اللغوية فى المستوى الجامعي.
Tactics - criminalistic ensuring counteraction to criminal offenses of terrorist orientation
Authors:   L.N.Gumilyov Eurasian National University, Sembekova B.R.
Published: February 2021

Counteraction to terrorism and extremism, definition of their system is caused by improvement of a tactical arsenal of disclosure process, investigation and prevention of criminal offenses of terrorist orientation, development of effective methods for obtaining reliable, full, objective information in the course of collecting, a research, fixing and assessment of proofs. The attention to application of a method of algorithmization of investigative, secret investigative actions and investigation and search operations, proceeding from the situational caused problems of tactical and strategic character defining efficiency of application of methods of tactical combinations and tactical operations is focused. Application of methods of tactical combinations and tactical operations defines efficiency of counteraction to terrorism and extremism. Tactical combinations and tactical operations, their realization in the system of counteraction to terrorism and extremism by situation analysis of the criminal offenses of terrorist orientation promoting definition of an algorithm of investigative, secret investigative actions and investigation and search operations are shown.
Evidências sobre o Uso de Práticas Alternativas e Complementares no Tratamento Convencional de Neoplasias Mamárias
Authors: Cruz Cíntia Tavares , Barros Nelson Filice de , Hoehne Eduardo Luiz
Published: February 2021

O objetivo deste estudo foi identificar a prevalência do uso de práticas alternativas e complementares (PACs) entre pacientes com neoplasias mamárias tratadas no Ambulatório de Mama do CAISM/Unicamp, bem como os motivos para o uso desses tratamentos. Foram realizadas entrevistas dirigidas, por telefone, com 82 pacientes com neoplasias de mama em tratamento convencional, seguidas de entrevistas em profundidade, com cinco pacientes que afirmaram usar PACs na primeira fase. A maioria das entrevistadas encontra-se entre 50 e 60 anos de idade, casadas, brancas e católicas, com baixa renda familiar mensal e baixo nível de escolaridade. Do total, 90,2% negam usar algum tipo de PAC; porém 96,3% fazem menção ao uso de pelo menos uma prática no decorrer das entrevistas. A prática mais utilizada é a oração, seguida de grupos de apoio, ervas e dieta. As pacientes esperavam que as práticas funcionassem como tratamento adjuvante da doença e dos efeitos colaterais trazidos pelo tratamento convencional e não como curativas. As entrevistadas na fase qualitativa relataram melhoras dos sintomas com o uso de PAC, afirmaram não ter pensado na possibilidade de efeitos colaterais e não declarar o uso de PAC aos seus médicos oncologistas. A oração apareceu como a PAC mais utilizada. O uso de PAC apresentou caráter adjuvante ao tratamento convencional e foi relacionado com as melhoras dos efeitos colaterais decorrentes desse tratamento. Ressalta-se a importância da formação dos profissionais de saúde quanto ao uso de PAC e a escassez de informações existentes sobre esta temática no Brasil.
Estudo Epidemiológico de Pacientes com Tumor de Ovário no Município de Jundiaí no Período de Junho de 2001 a Junho de 2006
Authors: Luiz Bianca Mello , Miranda Patrícia Frodl , Maia Edna Marina Cappi , Machado Rogério Bonassi , Giatti Milzen Jessel Lavander , Antico Filho Armando , Borges João Bosco Ramos
Published: February 2021

O estudo teve como objetivo avaliar o perfil sociodemográfico e reprodutivo de mulheres com diagnóstico de câncer de ovário na cidade de Jundiaí, São Paulo, no período de junho de 2001 a junho de 2006. Foi realizado um estudo descritivo, retrospectivo, através de inquérito, de todos os casos de tumores malignos do Laboratório de Anatomia Patológica do Sistema Único de Saúde (SUS) de Jundiaí e do Ambulatório de Saúde da Mulher da Secretaria de Saúde do Município de Jundiaí, a fim de identificar o perfil dos casos de tumor de ovário maligno. As características sociodemográficas das pacientes portadoras de tumor de ovário evidenciaram que: a média de idade no momento do diagnóstico foi de 55 (± 13,5 anos); a média de nível educacional no momento do diagnóstico foi de 5,8 (± 3 anos); e a maior prevalência foi de mulheres casadas e de raça branca. As características reprodutivas das pacientes portadoras de tumor de ovário evidenciaram que: a média de idade da menarca foi de 13 (± 1,6 ano); a maior prevalência foi de multiparidade; houve aumento de peso desde a idade do diagnóstico até a idade atual; a média de tempo de amamentação foi de 8,6 meses (± 6,5 meses); e houve maior prevalência de mulheres que fizeram uso de anticoncepcional hormonal oral.
"Cirurgia Adjuvante" no Tratamento do Tumor Estromal Gastrointestinal Metastático: um Novo Conceito
Authors: Valadão Marcus , Linhares Eduardo , Vilhena Bruno , Guimarães Denise , Ferreira Carlos Gil
Published: February 2021

Os recentes avanços no tratamento dos tumores estromais gastrointestinais (GIST) foram responsáveis pela mudança da história natural da doença. O melhor conhecimento dos mecanismos moleculares foi fundamental para o desenvolvimento de droga alvo-molecular dirigida capaz de obter resultados, até então, não alcançados em nenhum tratamento de tumor sólido. A introdução do imatinibe na prática clínica modificou não só a sobrevida dos portadores de GIST metastático, como também foi responsável por quebras de paradigmas bem estabelecidos; porém, apesar de o tratamento da doença metastática ser baseado na utilização do imatinibe, o papel do cirurgião, nesse contexto, tem sido revisado, havendo alguns indícios de que a cirurgia de resgate na doença metastática possa trazer benefícios a grupos selecionados de pacientes. Dessa forma, um novo conceito se estabelece, o da "cirurgia adjuvante"; ou seja, uma estratégia terapêutica que visa a otimizar os resultados do tratamento do GIST metastático.
A Importância dos Ácidos Graxos Ômega-3 no Câncer
Authors: Carmo Maria Carmen Neves Souza , Correia Maria Isabel Toulson Davisson
Published: February 2021

Os ácidos graxos poli-insaturados de cadeia longa eicosapentaenoico (EPA) e docosahexaenoico (DHA), presentes nos peixes ricos em gordura e no óleo de peixe, têm impacto no câncer. Eles podem inibir a carcinogênese, retardar o crescimento de tumores e aumentar a eficácia da radioterapia e de várias drogas quimioterápicas, conforme demonstrado por estudos in vitro, experimentais com animais e alguns ensaios clínicos. Os ácidos graxos ômega-3 (AGs n-3), especialmente os EPAs, parecem ter importante papel na caquexia induzida pelo câncer. Vários mecanismos de ação foram propostos para explicar como os AGs n-3 podem modificar o processo de carcinogênese, tais como: supressão da biossíntese dos eicosanoides derivados do ácido araquidônico; influência na atividade do fator de transcrição nuclear, na expressão gênica e nas vias de transdução de sinais; alteração do metabolismo do estrogênio; aumento ou diminuição da produção de radicais livres e espécies reativas de oxigênio e; influência nos mecanismos envolvendo a resistência à insulina e a fluidez das membranas. Os objetivos deste estudo foram descrever os principais benefícios da terapêutica nutricional baseada na utilização da suplementação de AG n-3 em pacientes oncológicos, abordando essencialmente a via metabólica desse ácido graxo. Embora os estudos in vitro e os experimentos com animais tenham mostrado que os AGs n-3 podem ser úteis no tratamento e na prevenção do câncer, os ensaios clínicos, no que se refere ao tratamento, são poucos e têm mostrado resultados conflitantes.
PEMBERDAYAAN REMAJA MELALUI IBM PELATIHAN PENGOLAHAN NATA DE SOYA DI DESA GITIK ROGOJAMPI BANYUWANGI
Authors: Triasih Dyah , Priyadi D.A.
Published: February 2021

Desa Gitik adalah salah satu desa dalam di wilayah kecamatan Rogojampi kabupaten Banyuwangi. Penduduk Gitik sebagiaan besar berprofesi sebagai pengusaha tahu. Peningkatan produktivitas tahu memberikan dampak negatif terhadap lingkungan yaitu pencemaran lingkungan. Pencemaran lingkungan disebabkan produsen tahu membuang limbah tahunya ke lingkungan tanpa melakukan pengolahan lebih lanjut. Oleh karena itu diperlukan suatu upaya untuk mengendalikan cemaran limbah tahu dengan cara memberikan pelatihan pembuatan Nata de soya dari whey tahu sehingga dapat memberikan nilai tambah (added value), meningkatkan pendapatan masyarakat. Metode yang digunakan adalah sosialisasi dan penyuluhan, pelatihan pembuatan Nata De Soya (NDS), dan evaluasi kegiatan. Hasil dari pengabdian masyarakat bahwa mitra menunjukkan hasil yang positf dan mampu menerapakan materi yang diberikan selama pelatihan.
HAND SANITIZER OTOMATIS UNTUK PENCEGAHAN PERSEBARAN PANDEMI COVID-19 DI KOTA TEGAL
Authors: Hidayattullah Muhammad Fikri , Nishom M. , Abidin Taufiq , Wibowo Dega Surono , Hapsari Yustia
Published: February 2021

Masa new normal adalah sebuah babak baru kehidupan manusia pasca diberlakukannya periode darurat nasional pandemi COVID-19. Beberapa fasilitas publik yang sebelumnya ditutup di masa new normal kembali dibuka, di antaranya adalah masjid. Salah satu protokol kesehatan yang harus dijalankan di tempat-tempat umum, salah satunya masjid, adalah adanya tempat cuci tangan atau penyediaan hand sanitizer. Namun, tuas hand sanitizer yang ditekan secara bergantian malah bisa menjadi sarana persebaran COVID-19 karena tertinggalnya virus di tuas hand sanitizer tersebut. Oleh karena itu, melalui kegiatan Pengabdian Kepada Masyarakat (PKM) ini dikembangkanlah sebuah alat hand sanitizer otomatis yang dapat menyemprotkan cairan hand sanitizer tanpa menyentuh tuas sprayer. Alat tersebut dibagikan ke dua masjid di Kota Tegal, yaitu masjid Ibnu Sirin dan masjid Abu Abakar Ash-Shiddiq. Tim PKM memberikan penjelasan mengenai fungsi dan teknis penggunaan alat. Setelah mendapatkan penjelasan dan arahan dari tim PKM, takmir masjid langsung memanfaatkan alat tersebut dan memasangnya di depan pintu masuk masjid. Alat ini mampu memberikan dukungan perlindungan kesehatan bagi jama’ah masjid agar terhindar dari COVID-19.
ANALISIS KESIAPAN DAN EVALUASI PENGELOLAAN LABORATORIUM IPA BERBASIS TEKNOLOGI DI ERA REVOLUSI INDUSTRI 4.0
Authors: Nulngafan Nulngafan , Khoiri Ahmad
Published: February 2021

Kondisi ideal laboratorium IPA disekolah yang memenuhi PP RI No.19 Tahun 2005 telah menetapkan 8 standar laboratorium  dan Permendiknas No 24 Tahun 2007 standar Sarana dan Prasarana pendidikan, namun faktanya tidak demikian kondisi ketersediaan dan kesiapan laboratorium IPA belum berfungsi dengan baik, Desain Based Research (DBR) yang terdiri dari: Identifikasi dan analisis masalah, Perancangan solusi, Siklus berulang dalam pengujian dan penyempurnaan rancangan, serta Refleksi untuk menghasilkan prinsip-prinsip desain dan implementasi. Metode pengumpulan data melalui survei, angket kesiapan dan ketersediaan Laboratorium IPA dan dokumentasi. Teknik analisis data menggunakan analisis validasi produk, keterlaksanaan produk, analisis repons serta keefektifan produk kebijakan yang ditawarkan. Hasil analisis Kesiapan Laboratorium IPA berbasis teknologi kriteria belum mencapai 50% artinya kurang siap, Evaluasi penyelenggaraan Laboratorium IPA tertinggi diperoleh sekolah negeri wilayah kota sebesar 85% kategori sangat baik, sedangkan skor terendah diperoleh sekolah swasta wilayah desa sebesar 66,25% kategori cukup, sedangkan ketersediaan Sarana dan prasarana Laboratorium IPA telah memenuhi standar Permendiknas No 24 Tahun 2007 sebesar 78,3% kategori baik. Perlunya kebijakan penelitian pendidikan untuk dapat mengatasi masalah laboratorium IPA di era revolusi industry 4.0 berupa revitalisasi pengelolaan Laboratorium IPA pada sistem cyber dan laboratorium virtual berbasis Teknologi.
Случаи гипертонии в штате Амапа в период с 2006 по 2012 год
Authors: Feio Stefanie Cecilia Passinho , Fecury Amanda Alves , Oliveira Euzébio , Dendasck Carla Viana , Dias Claudio Alberto Gellis de Mattos
Published: February 2021

Артериальная гипертензия – это необычное повышение давления, которое кровь оказывает на стенки кровеносных сосудов человека. Повышенное кровяное давление происходит молча, так что ваши симптомы не могут ощущаться в первую очередь. Лечение гипертонии может быть сделано с помощью фармацевтических препаратов или с помощью простых действий, таких как изменение ежедневных привычек к более здоровым привычкам. Целью данного исследования является показать количество случаев гипертонии в штате Амапа в период с 2006 по 2012 год. Исследование проводилось в базе данных DATASUS (http://datasus.saude.gov.br/). Число случаев гипертонии в Амапа в период с 2006 по 2012 год сильно варьируется в зависимости от лет, происходящих больше в столице штата; у женщин выше, чем у мужчин; в возрастной группе от 50 до 69 лет выше, чем число случаев заболевания в других возрастных группах; и в большинстве случаев не имеют влияния избыточного веса, сидячего образа жизни или курения. В Амапа случаи гипертонии сохраняются из-за отсутствия приверженности лечению или неправильного лечения, вызванного отсутствием информации о тяжести измененного давления на здоровье. После постановки диагноза женщины имеют большую личную медицинскую помощь и более широкое поддержание лечения. Хронические неинфекционные заболевания предлагают более высокий риск для населения с большей возрастной группой. Эффективной причиной случаев гипертонии в Амапа, как представляется, генетический фактор и стресс, вытесняя такие факторы, как избыточный вес и сидячий образ жизни. Снижение уровня школьного обучения приводит к небезопасности на работе, повышению стресса и изменению артериального давления. Курение не является основным фактором, поскольку его национальное сокращение было достигнуто с помощью образовательных кампаний молодежи. К сожалению, случаи затруднений в доступе к здоровью, диагностике и лечению гипертонической болезни остаются реальными в государстве.
Perspectivas da imunoterapia em pacientes com câncer de pulmão metastático
Authors: Motté Carolina de Paula , Barbosa Amanda Graziele Silva , Soares Amanda Katherine Vieira Lima , Cavalcanti Ana Carolina Damasceno , Bezerra Ana Caroline Carvalho , Assis Larissa Duarte Peixoto de , Prates Milenna Luiza da Silva , Souza Rafael de , Romanichen Talita Cristina , Vasconcelos Gilberto Loiola de
Published: February 2021

Objetivo: Avaliar repercussões da imunoterapia em pacientes portadores de câncer de pulmão metastático através de dados da literatura vigente. Métodos: Utilizando a base de dados Biblioteca Virtual de Saúde e os Descritores em Ciências da Saúde foram triados 12 artigos para análise. Resultados: O câncer de pulmão manifesta-se por meio de sintomas específicos e de sintomas sistêmicos. Tendo em mente a elevada incidência de mortalidade desta neoplasia, os tratamentos empregados atualmente são diversificados e, dentre os quais, a variante que apresenta a maior probabilidade de cura é a ressecção cirúrgica, com associação de tratamentos adjuvantes. Entre os artigos analisados, 75% explanaram sobre tratamento com compostos de platina e imunoterapia anti-PDL1, os quais evidenciaram resultados favoráveis no manejo de pacientes com câncer de pulmão de células não pequenas (NSCLC) ou câncer de pulmão de pequenas células (SCLC) avançados. Observou-se, ainda, que a associação do inibidor PD1 a compostos como o ALT-803 (superagonista do IL-15) em pacientes com NSCLC com suporte ambulatorial se mostrou ser uma combinação tolerável e segura. Conclusão: O desenvolvimento da imunoterapia contra o câncer elevou significativamente a possibilidade de manipular células imunológicas em pacientes diagnosticados com neoplasias metastáticas, com o propósito de atenuar a propagação da doença e prolongar a vida do paciente através da potencialização de suas funções imunológicas.
Effect of the protection measures established by the peruvian government to prevent the Coronavirus in the Barranca district during the second wave of infections [Efecto de las medidas de protección establecidas por el gobierno peruano para prevenir el Coronavirus en el distrito de Barranca durante la segunda ola de contagios]
Authors: Cruz Nieto Dante , Rodriguez Espinoza Ronald , Valderrama Rios Olga , López Balarezo Jorge , Ramos Pacheco Ronald , Castañeda Chirre Elvira , Yovera Saldarriaga José , Meyhuey Pala Patricia
Published: February 2021

The objective of the investigation is to establish the effect of the protection measures established by the government to reduce the contagion by Covid -19 in the district of Barranca during the second wave of infections. Data were collected on compliance with protection measures such as distancing, use of masks, visors and disinfection with alcohol in public places such as streets, markets, banks and parks. For this, data collection instruments based on visual inspection were used to verify the appropriate use of protection measures, as well as a survey regarding the use of alcohol as a disinfectant; and the data obtained was processed through basic statistics and correlation with the data reported by the Ministry of Health of positive infections by Covid-19. It was determined that there is a growth relationship between compliance with protection measures and the number of positive infections, with correlation coefficients for distance of 0.7458, use of 0.6710 masks, 0.8784 visors and use of alcohol as a disinfectant of 0.7310. Regarding the analysis of variance, it is obtained that the use of visors influences the number of positive infections, which is why it is concluded that maintaining distance, in addition to the use of masks and disinfectant alcohol are effective measures to control the number of infections per coronavirus.
Lime-based Sacrificial Layers – Evaluation of a Traditional Conservation Method Applied in an Urban Environment
Authors: Pinter Farkas , Fuchs Katharina
Published: February 2021

The use of modified lime slurry as a sacrificial layer to protect the original porous substrate has a long tradition in the practice of building and monument conservation in Austria. This paper presents the results of analyses performed on the Natural History Museum Vienna to get more insight into the long-term performance of this conservation method. Stone surfaces on the facade and roof area, covered with an acrylic tempered lime sacrificial layer and subsequently made water-repellent, were tested in situ and in the laboratory. Whilst coatings in the exposed zones were completely vanished in certain areas, the samples from the facade were in a good condition even after nearly twenty years of exposure. Hydrophobic activity could be verified up to a depth of five mm in the porous stone substrates. Despite the general good state of preservation of most surfaces, the existence of highly hydrophobic substrates will definitely restrict the implementation of any future sustainable conservation effort.
PROFESIONALIZACIJA SLOVENSKE VOJSKE – CILJ ALI POT
Authors: KOTNIK IGOR
Published: February 2021

Projekt Prehod na poklicno vojsko, dopolnjeno s prostovoljno rezervo, s kratico PROVOJ, je bil začet leta 2003 in predčasno končan leta 2007. Ali je bila naloga profesionalizacije SV torej že opravljena? Ocenjujemo, da proces profesionalizacije SV še zdaleč ni končan. Pot od poklicne proti k zares profesionalni SV nikakor ne bo kratka in lahka, prej dolgotrajna, zavita, strma in spolzka ter polna pasti in izzivov. V prispevku namenjamo posebno pozornost pravilnemu dojemanju temeljnega poslanstva SV, premagovanju zapuščine obvezniške vojske, razumevanju omejitev poklicne vojske, profesionalizaciji v pogojih finančnih omejitev, profesionalni integriteti pripadnikov SV, profesionalizaciji in obvladovanju interesnih nasprotij, zunanjemu in notranjemu nadzoru vojaške profesije, profesionalizaciji prek stalnega izobraževanja ter profesionalizaciji kot nikoli zares končanem procesu. V tem kontekstu moramo na področju profesionalizacije poklicne SV ohraniti ustrezno čuječnost in zavzetost, preden se na nekatere nedoslednosti in nepravilnosti, na katere opozarja prispevek, dokončno navadimo oziroma ohranimo nadzor nad nekaterimi do zdaj manj uspešnimi vidiki tega procesa in njihovimi posledicami.

The project »Transition to Professional Armed Forces Complemented with Contractual Reserve« (PROVOJ) was launched in 2003 and concluded premature- ly in 2007. Has thus the mission of Slovenian Armed Forces (SAF) professionali- zation been completed? We estimate that SAF professionalization is far from being complete. The path from career to truly professional Slovenian Armed Forces will certainly not be short and easy, but rather time consuming, winding, steep, slippery and full of traps and challenges. In the article, special attention is devoted to a proper understanding of the basic SAF mission, the overcoming of the conscription system heritage, understanding of professional armed forces restrictions, professionaliza- tion in austerity conditions, professional integrity of SAF members, professionali- zation and management of conflicts of interests, internal and external control of the profession of arms, professionalization through continuous training and professio- nalization as a never-really-completed process. In this context, a proper amount of vigilance and commitment should be preserved in the professionalization of career armed forces, before we completely adapt to certain inconsistencies and irregulariti- es underscored in this article and not to preserve the same level of control over some hitherto less successful aspects of this process and their consequences.
(NE)OBSTOJ SLOVENSkE VOJAŠkE IDENTITETE
Authors: PREBILIČ VLADIMIR , JUVAN JELENA
Published: February 2021

Kodeks vojaške etike Slovenske vojske (SV) med drugim določa: »pripadniki Slovenske vojske pri opravljanju vojaške službe /…/ spoštujejo slovensko vojaško zgodovinsko tradicijo in skrbijo za ohranjanje nacionalnega vojaškega zgodovinske- ga spomina« (Kodeks, 2009). Pri tem se nedvomno vprašamo, kaj sploh je slovenska vojaška zgodovinska tradicija, ki jo morajo pripadniki SV spoštovati, in kakšen je omenjen vojaški zgodovinski spomin. Časovna opredelitev zgodovinskega spomina je pri tem nujna. Do kod v preteklosti seže slovenski vojaški zgodovinski spomin? Kateri so dejavniki, ki so pomembno vplivali nanj in so posledično opredelili slovensko vojaško tradicijo? Kaj predstavlja slovensko vojaško tradicijo? Ali med dejavnike njenega oblikovanja prištevamo zgolj zmagovite dogodke ali vse vojaške izkušnje, tudi tiste, manj uspešne? Z drugimi besedami – katere so vrednote, ki določajo vojaško tradicijo nekega naroda? Na ta vprašanja bi morala imeti Slovenska vojska pripravljene skrajno jasne odgovore, ki bi omogočali tudi njeno jasno vizijo in bi pomembno vplivali na raven samopodobe slovenskih oboroženih sil ter na njen položaj v slovenski družbi. Žal pa se zdi, da je to področje v veliki zadregi, ki se kaže že v izhodišču – kdo pravzaprav lahko opredeli slovensko vojaško tradicijo in kako se bo ta utrjevala v prihodnje. The Military Code of Ethics of the Slovenian Armed Forces (SAF) states that: » members of the Slovenian Armed Forces /. / – have to respect Slovenian military tradition and promote the preservation of national military history memory« (Code, 2009). This certainly raises a question of how the military history tradition of the SAF is defined and what can be understood as a military history memory. In this respect, time perspective should be considered. How far back does Slovenian military history memory go? Which facts have importantly influenced it and, consequently, defined Slovenian military tradition? What is understood as Slovenian military tradition? Have only victories shaped military tradition, or was it also other military experi- ences, even the less successful ones? What are core values which define a nation's military tradition? The SAF should have very clear answers to these questions. Unambiguous answers would significantly influence the self-image of the SAF and its position in the Slovenian society. Unfortunately, there seems to be a great quandary in the very core of this issue – who is actually responsible for defining Slovenian military tradition and how it can be nurtured in the future.
DEVELOPMENT OF METHODS OF CALCULATIONS
OF N(h)-PROFILES OF THE IONOSPHERE BASED ON THE DATA
OF IONOGRAMS OF VERTICAL SENSING
Authors: Zhbankov G. A.
Published: February 2021

Two new methods are proposed for calculating the N(h)-profiles of the ionosphere from the data of vertical sounding ionograms based on numerical trajectory calculations in a mag-netically active medium. It has been shown experimentally that the model ionogram calculat-ed from the profiles obtained by both described methods is almost exactly consistent with the experimental one. Depending on the task, you can specify the choice of method. With some modification, they can be used as an automatic procedure for calculating N(h)- profiles.
CONFIGURABLE HARMONIC FILTERS
FOR SHORT-WAVE TRANSMITTERS
Authors: Zinovyev A. G. , Shestakov I. A.
Published: February 2021

Harmonic filters of short-wave transmitters, tunable in the frequency range using discrete variable capacitors, are presented. A comparison of a harmonic filter based on tunable LC low-pass filters with inductive coupling between the filter inductors is carried out with a similar harmonic filter, each LC low-pass filter of which con-tains an additional capacitive coupling capacitor connected between the two filter links and significantly changed the parameters of the harmonic filter.
Guidelines for Promoting the Implementation of Pharmaceutical Quality Systems at EAEU Enterprises Through the Management of the Engagement of Production Personnel
Authors: Smirnov V. A. , Goryachkin V. V. , Shestakov V. N. , Abramovich R. A.
Published: February 2021

Introduction. The publication is devoted to the topical organizational and personnel issues of the implementation of the pharmaceutical quality system (PQS). The relevance of the study is due to the high importance of quality assurance in the development, production and release of drugs into circulation.

Aim. The aim: to develop guidelines for organizational and personnel assistance in the implementation of pharmaceutical quality systems at enterprises of the Eurasian Union (EAEU) for the production of medicines (drugs) through the toolkit for engaging production personnel in the development of PQS.

Materials and methods. Personnel engagement was assessed based on the engagement index; the benchmarking method was used when studying the impact of the engagement of production personnel on the economic indicators of corporate development (indicators of engagement and related economic indicators of “Akrikhin”, “Ozon” were compared with a panel of similar indicators for 12 pharmaceutical enterprises of the EAEU).

Results and discussion. The important role of ensuring an increase in the engagement of production personnel in the development of PQS as a tool for sustainable provision of the effectiveness of the implementation of PQS and standards of good manufacturing practice (GMP) at drug production enterprises is stated. Taking into account the experience of forming quality circles in classical Japanese management, an innovative toolkit for managing the engagement of production personnel is proposed, based on the formation of employee communities, coordination and management of their engagement and development through the corporate portal of a pharmaceutical enterprise, as well as membership in closed clubs of ‘quality leaders’.

Conclusion. Management of communities (small groups) of production workers is considered as a tool for improving the organizational and personnel support for the implementation and improvement of PQS / GMP at the EAEU pharmaceutical manufacturers. Through the communities, it is proposed to simultaneously manage the engagement, loyalty and job satisfaction of production personnel; community members, through the exchange of best manufacturing practices, ideas and opinions on the development of PQS and the improvement of nuclear quality assurance practices, will stimulate themselves and other production workers to consistently ensure the quality of manufactured drugs. The expected result is a steady increase in the quality of manufactured drugs, adherence of production personnel to the quality philosophy, creation of conditions for the growth of labour productivity of production personnel of pharmaceutical enterprises.