bluuebunny/crossref_metadata_2025 huggingface dataset:
Antecedents of the adoption of Social Media Marketing by micro and small enterprises
Authors: Gouveia Renata Edvania Costa , Aguiar Edvan Cruz
Published: September 2023

The adoption of Social Media Marketing (SMM) is increasingly present in the daily life of companies. However, little is known about this phenomenon in the context of micro and small businesses (MSEs). The research aimed to analyze the SMM adoption process by MSEs, based on a study with 338 entrepreneurs linked to the Brazilian Micro and Small Business Support System (Sebrae), using Structural Equation Modeling. It was found that technical knowledge, cost reduction, and pressure from customers and competitors generate benefits perceived by entrepreneurs concerning the use of the tool, leading to a higher level of use. The work contributes to the step in which it brings evidence that helps to understand the determinants of adopting SMM in the context of MSEs.
COVID-19 severity stratification using quantitative computed tomography analysis
Authors: ÇİNKOOĞLU Akın , ESMAT Habib Ahmad , BOZDAĞ Mustafa , BAYRAKTAROĞLU Selen , CEYLAN Naim , SOYLU Mehmet , SAVAŞ Recep
Published: September 2023

Aim: This study aimed to examine the utility of computer-assisted quantitative assessment of chest

computed tomography (CT) images in the stratification of Coronavirus Disease 2019 (COVID-19)

severity.

Materials and Methods: This study was designed as a retrospective, single-center study and

included a total of 142 RT-PCR-confirmed COVID-19 patients. CT findings were visually evaluated

and noted for their morphology and distribution characteristics. Visual semi-quantitative score (VSS)

and computer-aided quantitative score (CQS) were calculated. The utility of the approach was

assessed based on its ability to predict the patients who would require intensive care.

Results: The presence of underlying fibrosis, air bubble sign, and co-occurrence of central and

peripheral lung area involvement were the CT findings that were significantly more commonly

encountered in patients with intensive care requirements during the follow-up period. We found a

significant positive correlation between total VSS and CQS (p
Features of credit behavior of Russian youth: trends and risks
Authors: Yarasheva Aziza , Alikperova Natalia , Markov Dmitry
Published: September 2023

The article discusses the current aspects of the credit behavior of Russians, including changes in the volume of borrowings over the past 4 years, as well as the dynamics of indebtedness, including overdue loans. Based on the results of the author’s sociological research (two measurements — in 2022 and 2023), the features of active actions and attitudes of young people in the field of debt behavior are identified. The analysis showed strengthening of the vector on the willingness to involve this age group of the population in credit practices. There was carried out a comparison of the attitudes of young people regarding the conditions under which evasion of obligations to repay debts is justified: 1) debts to credit institutions; 2) to relatives and acquaintances. The views of Russian youth on the censure for such evasion practices in Russian society are examined. The survey results show that the presence of a loan agreement of respondents contributes to formation of a more responsible behavior regarding compliance with payment deadlines, in contrast to the situation of the absence of debt (only with the intention to enter into debt relations). The position of young people in relation to the violation of loan repayment terms is different in different groups: the youngest respondents (17–20 years old) see more reasons for the possibility of non-repayment of the loan. Among the reasons why it is permissible, in the opinion of young people, not to repay debts, the most compelling for respondents are the situations when the loan was issued by fraudsters without the consent of the person himself (67%), in case of serious health problems and the need to spend on treatment (38%), if the lender increased the interest on the loan unilaterally (34%), in case of job loss (26%). Credit risks typical not only for young people, but also for all age groups of Russians are highlighted: deterioration of the “credit quality” of borrowers and risks of breach of obligations (non-payment and violation of repayment terms) on loans due to a decrease in real income.
Subjektorientierung unter Druck:
Authors: Mendl Hans
Published: September 2023

„Subjektorientierung“ hat sich seit der anthropologischen Wende in der Religionspädagogik zu einem zentralen Leitprinzip entwickelt. Historisch betrachtet ist das nachvollziehbar, denn damit verbindet sich die Absage an ein deduktives normatives und von außen gesteuertes Modell einer religiösen Bildung und Erzieh­ung. Das hohe Gut der Entscheidungsfreiheit des lernenden Subjekts lässt sich über viele Themenfelder und Prinzi­pien der Religionspädagogik hinweg nachweisen. Demgegenüber scheinen im gesellschaftlichen und pädagogi­schen Diskurs aktuell durchaus Postulate auf, die als unumstößliche Normative gelten. Vor allem beim Zukunfts­thema „Bildung für nachhaltige Entwicklung“ zeigt sich das Problem, wie auch schöpfungstheologisch als unaus­weichlich scheinende Postulate, die auch Konsequenzen für Handlungsformen und Lebensstiloptionen beinhalten, mit dem freiheitlich sich entscheidenden Subjekt in Einklang gebracht werden können. Der Beitrag formuliert hier entsprechende kritische Anfragen an eine eingeengt individualistisch gedeutete Subjektorientierung.
Veredas do Patrimônio Histórico Educacional
Authors: Conceição Joaquim Tavares da , Paulilo André Luiz
Published: September 2023

Este artigo apresenta um balanço historiográfico da produção em História da Educação a respeito do patrimônio histórico educacional, a partir de publicações prospectadas em revistas científicas, buscando contribuir para a compreensão do conjunto dos interesses que versam sobre a salvaguarda, custódia, pesquisa, valorização e difusão do patrimônio histórico educacional, dos arquivos escolares ou da educação e dos acervos institucionais ou pessoais de educadores. Os resultados apontam a concentração da produção e da sua veiculação, apesar da expansão e diversidade das iniciativas; valorização da temática com a publicação da produção em periódicos consolidados na área da educação e da história da educação e abrangência conceitual e dispersão dos referenciais teórico-metodológicos, apesar da predominância dos pressupostos da história cultural.
De chefe a chefe
Authors: Silva Vera Lucia Gaspar da , Scagliola Gabriel
Published: September 2023

Neste artigo, optamos por retratar uma espécie de engenharia que permeou a composição do acervo do Museu e Biblioteca Pedagógicos de Montevidéu em seus primeiros anos. Entre as coleções disponíveis, escolhemos as revistas pedagógicas, apresentando dados sobre sua composição, estratégias que colocam em evidência formas de operar, articulações políticas que envolvem muitas das escolhas e o valor deste tipo de impresso no período em destaque. Identificamos uma movimentação que pode ser lida como articulação nacional e estrangeira para composição do acervo, relações de seu diretor com autoridades de diferentes instituições e níveis, valor atribuído ao conteúdo veiculado em tais periódicos, conexões que indiciam sobre a circulação de ideias e estratégias que alimentaram a elaboração de projetos de escolarização em diferentes países.
Diálogos luso-brasileiros sobre o patrimônio educativo
Authors: Oliveira João Paulo Gama , Elvas Raquel Resende , Santana Sayonara Rodrigues do Nascimento
Published: September 2023

O objetivo do presente artigo é responder à seguinte pergunta: o que uma escola pública guardou no seu acervo ao longo de mais de um século de funcionamento? Para solucionar tal questionamento, analisaremos os acervos salvaguardados em um espaço de memória escolar português e outro brasileiro, a saber: o Museu Escolar Oliveira Lopes (Meol), localizado em Válega, e o Centro de Educação e Memória do Atheneu Sergipense (Cemas), da cidade de Aracaju. Entende-se que, mesmo com as diferenças existentes entre o Meol e o Cemas, ambos salvaguardam um conjunto de artefatos e documentos que ultrapassou a barreira do século e tornou-se acessível a diferentes grupos, além da comunidade escolar. São guardiões de uma “herança educativa” fundamental para o trato do patrimônio educativo luso-brasileiro.
Delimitação da área de conhecimento científico da educação superior
Authors: Werlang Rodrigo Pivetta , Trevisol Marcio Giusti
Published: September 2023

Introdução/Objetivo: Este artigo tem por objetivo delimitar o campo do conhecimento científico da área de educação superior nos acervos Capes Periódicos, SciELO e nos anais das reuniões nacionais da ANPEd, entre os anos de 2019 e 2022 com a finalidade de problematizar os temas emergentes tratados pela comunidade científica. A investigação parte da pergunta: quais temas têm pautado as pesquisas na educação superior? Metodologia: Trata-se uma pesquisa qualitativa, exploratória e bibliográfica. Os dados coletados foram analisados e organizados a luz da análise de conteúdo. A coleta dos dados foi realizada no portal Capes Periódicos, SciELO e nos anais das reuniões nacionais da ANPEd entre os anos de 2019 e 2022. Para a coleta foi utilizado como descritor educação superior com e sem aspas.  Ao todo foram selecionados 136 artigos, organizados nas seguintes categorias: Estado, políticas públicas e institucionais, Democratização da Educação Superior, Internacionalização, Formação docente e profissional, Pedagogia universitária e Avaliação da Educação Superior. Resultados: Como resultado percebemos que há vasta produção sobre Democratização da Educação Superior, seguido por debates sobre o Estado, políticas públicas e institucionais, questões relativas à Pedagogia universitária, Internacionalização e Formação docente e profissional. O descritor Avaliação da Educação Superior apresentou a menor quantidade de produções neste recorte temporal de 2019 a 2022. Conclusão: Por fim, a investigação apontou para a preocupação da comunidade investigativa com as políticas educacionais para a educação superior adotadas pelo governo brasileiro e os desafios frente as influências do neoliberalismo.
Análise comparativa dos processos de avaliação da qualidade do Ensino Superior
Authors: Daniel Eulanda Maria Pedro , Wives Leandro Krug , Lorandi Alexandra
Published: September 2023

Introdução/Objetivo: O presente artigo visa analisar as metodologias de avaliação da qualidade do ensino superior, utilizadas em cinco países: Brasil, Portugal, Moçambique, Estados Unidos e Reino Unido. Metodologia: Esta pesquisa é de cunho exploratório e faz uso da pesquisa documental e bibliográfica para examinar e comparar os objetos, objetivos, instrumentos, indicadores e critérios de avaliação, além de políticas e diretrizes estabelecidas para guiar o processo de avaliação da qualidade do ensino superior. Resultados: Os resultados demonstram que há uma uniformidade na maneira como as avaliações são conduzidas, sugerindo um esforço global em garantir a qualidade e promover a excelência acadêmica em nível internacional. Conclusão: Existem diferenças nos detalhes e na implementação das avaliações em cada país estudado, refletindo diferenças culturais e nas necessidades e prioridades específicas de cada contexto educacional. Portanto, para futuros trabalhos é recomendado a realização de estudos comparativos mais aprofundados entre os países, bem como a inclusão de novos indicadores de avaliação e a utilização de tecnologias inovadoras, como a inteligência artificial. O intuito é alcançar maiores patamares qualitativos que garantam a excelência do ensino superior em nível internacional.
70 Yaş ve Üzeri Erkek Cinsiyette Kemik Mineral Dansitesinin İnsülin Benzeri Büyüme Faktörü 1 ve Estradiol Düzeyleri ile İlişkisi
Authors: ÖNDER Çağatay Emir , YILMAZ Nisbet
Published: September 2023

Amaç: Osteoporoz düşük kemik kütlesi ve kemiğin mikromimarisinin bozulması ile karakterize bir hastalıktır. Kadınlarda osteoporozun daha sıklıkla görülmesi, erkeklerde göz ardı edilmesine yol açmıştır. Bu çalışmanın amacı, 70 yaş ve üzeri erkek cinsiyette kemik mineral dansitesinin insülin benzeri büyüme faktörü 1 (IGF-1) ve Estradiol düzeyleri ile ilişkisini değerlendirmektir.

Gereç ve Yöntem: Çalışma, 2014-2015 arasında 28 hasta (osteoporoz ve osteopeni) ve 23 kontrol grubu olarak 51 kişi ile yapıldı. Vakaların diyette 3 günlük ortalama kalsiyum alımları ve fiziksel aktivite durumları kaydedildi. Kemik mineral yoğunluğu (KMY), albumine göre düzeltilmiş serum kalsiyum düzeyi (Alb-sCa), fosfor (P), paratiroid hormon (PTH), 25 (OH) D3 vitamini, total testesteron, estradiol (E2), IGF-1 ve 24 saatlik idrar Ca düzeyleri ölçüldü.

Bulgular: Hasta ve kontrol grubu arasında yaş, vücut kitle indeksi (BMI), fiziksel aktivite ile Alb-sCa, P, PTH ve 24 saatlik idrar Ca düzeyleri yönünden fark bulunmazken (p>0.05); kontrol grubunun boy, kilo, 3 günlük ortalama kalsiyum alımları ile 25 (OH) D3 vitamini düzeyi anlamlı olarak yüksekti (p
AWF-YOLO: enhanced underwater object detection with adaptive weighted feature pyramid network
Authors: Guo Qianren , Wang Yuehang , Zhang Yongji , Qin Hongde , Qi Hong , Jiang Yu
Published: September 2023

Underwater scenarios are influenced by various factors such as light attenuation, scattering, and absorption, which degrade the quality of images and pose significant challenges for underwater object detection in marine research and ocean engineering. To address these challenges, we propose a novel adaptive-weight feature detection framework based on YOLOv8, called AWF-YOLO, designed to detect objects in turbid underwater scenarios accurately. AWF-YOLO incorporates several key components to improve detection performance. Firstly, a novel adaptive-weight feature pyramid network is introduced to facilitate the fusion of multi-scale feature semantics. In addition, an adaptive-weight feature extraction module is proposed to enhance underwater object detection by capturing relevant and discriminative information to enhance feature extraction further. We integrate a dedicated small object detection head into the detection network to overcome the challenges associated with detecting small objects in complex underwater scenarios. This component focuses on effectively identifying and localizing small objects, leading to improved overall detection accuracy. Extensive experiments conducted on the detection underwater objects dataset demonstrate that the proposed AWF-YOLO achieves significant performance improvements, thus making it highly suitable for complex and dynamic underwater scenarios.
Quantum and Quantum-Inspired Stereographic K Nearest-Neighbour Clustering
Authors: Modi Ark Kumar , Viladomat Jasso Alonso , Ferrara Roberto , Noetzel Janis , Deppe Christian , Schädler Maximilian , Fung Fred
Published: September 2023

Nearest-neighbour clustering is a simple yet powerful machine learning algorithm that finds natural application in the decoding of signals in classical optical-fibre communication systems. Quantum k-means clustering promises a speed-up over the classical k-means algorithm; however, it has been shown to currently not provide this speed-up for decoding optical-fibre signals due to the embedding of classical data, which introduces inaccuracies and slowdowns. Although still not achieving an exponential speed-up for NISQ implementations, this work proposes the generalised inverse stereographic projection as an improved embedding into the Bloch sphere for quantum distance estimation in k-nearest-neighbour clustering, which allows us to get closer to the classical performance. We also use the generalised inverse stereographic projection to develop an analogous classical clustering algorithm and benchmark its accuracy, runtime and convergence for decoding real-world experimental optical-fibre communication data. This proposed `quantum-inspired' algorithm provides an improvement in both the accuracy and convergence rate with respect to the k-means algorithm. Hence, this work presents two main contributions. Firstly, we propose the general inverse stereographic projection into the Bloch sphere as a better embedding for quantum machine learning algorithms; here, we use the problem of clustering quadrature amplitude modulated optical-fibre signals as an example. Secondly, as a purely classical contribution inspired by the first contribution, we propose and benchmark the use of the general inverse stereographic projection and spherical centroid for clustering optical-fibre signals, showing that optimizing the radius yields a consistent improvement in accuracy and convergence rate.
The Role of Pseudocereals and Nontraditional Crops in Contributing to Food Gap in Egypt, A Review
Authors: M. Hassona Mohamed
Published: September 2023

Egypt faces numerous challenges in achieving food and nutritional security, due largely to its unique geography, water stress, and population growth. However, nontraditional crops and pseudo cereals such as buckwheat, quinoa, sorghum, teff, and millet offer promising avenues for sustainable agricultural development and improved nutrition. These crops exhibit high tolerance to adverse environmental conditions such as soil salinity and drought and are rich in essential nutrients like protein, amino acids, and vitamins. They also present an economic advantage due to their short growing seasons and adaptability to marginal lands. Recent advancements in remote sensing and Geographic Information Systems (GIS) technology, along with crop simulation models, provide further opportunities for optimizing land and water resources for these nontraditional crops. Their exceptional nutritional values, including low glycemic indices and gluten-free properties, make them well-suited to address current health challenges, such as malnutrition and the increasing prevalence of non-communicable diseases. The study emphasizes the need for further research to investigate land suitability, water management, and economic viability for the cultivation and commercialization of these crops. By leveraging these opportunities, Egypt has the potential to not only close its food gap but also improve overall nutritional well-being, contributing to both food security and sustainable agriculture.
Nutrition Status of Female Winter Sports Athletes
Authors: Jiménez-Casquet María José , Conde-Pipo Javier , Valenzuela-Barranco Ignacio , Rienda-Contreras Raquel , Olea-Serrano Fatima , Bouzas Cristina , Tur Josep A. , Mariscal-Arcas Miguel
Published: September 2023

Eating disorders, especially restrictive eating, are common among female athletes. There are two main types of winter sports, those that are practised outdoors on snow (-25 to +5ºC and 2500 m), such as alpine skiing or snowboarding, and those that are practiced indoors on ice (5-10º C at low altitude), such as figure skating and ice hockey. The aim of this research was to identify the nutritional status and potential risk of female athletes practising winter sports considering the altitude of training. The sample was composed of 58 women (aged 19.81 years (SD: 12.61) who were competitors in some winter sports. Anthropometrics and nutritional variables were taken. Statistically significant differences were found between groups for all the characteristics except thigh skinfold and neither group had an EI that matched their TEE. Both groups met at least 2/3rd of the RDI for all minerals and vitamins, except iodine, fluorine, vit D, E and retinol. This study suggest that female winter sports athletes have insufficient energy, vitamin and mineral intake that can be worsened by altitude.
Altered Peripheral Amino Acid Profile Has Pivotal Role in Controlling Pro- and anti- Inflammatory Responses in Celiac Disease
Authors: Fallah Shayan , Asri Nastaran , Nikzamir Abdolrahim , Ahmadipour Shokoufeh , Sadeghi Amir , Rostami Kamran , Rostami-Nejad Mohammad
Published: September 2023

The amino acids (AAs) and vitamins imbalances are observed in celiac disease (CD). This study evaluated the plasma profile of vitamin A and AAs and the expression level of IL-2, IL-4, IL-10, IL-12 and TGFβ in CD patients. A total of 60 children and adults with CD and 40 healthy controls (HCs) were included. Plasma profile of Vitamin A and AAs and the mRNA expression levels of target genes were assessed. Active adult patients exhibited a decrease in Vitamin A levels (p=0.04) and an increase in IL-2 (p=0.008) and IL-12 (p=0.007) mRNA expression compared to HCs. Treated adult patients showed elevated Serine (p=0.003) and Glycin (p=0.04) levels, as well as increased IL-12 (P<0.0001) mRNA expression, and a decrease in Tryptophan (p=0.04) levels relative to the controls. Additionally, treated adult patients had higher plasma levels of Threonine compared to both active (p=0.04) and control (p=0.02) subjects, and increased mRNA expression of IL-4 (p=0.01) in comparison to active patients. In active children with CD, IL-2 mRNA level was found to be higher than in controls (P<0.0001) and in treated children (p=0.005). Treated children with CD exhibited decreased plasma levels of Tryptophan (p=0.01) and Isoleucine (p=0.01) relative to the controls, and increased mRNA expression of TGFβ (p=0.04) relative to active patients. Managing Retinoic acid levels is crucial to alleviate intestinal inflammation of CD patients. Threonine, tryptophan, and Isoleucine are potential therapeutic options for treating CD, and targeting serine, histidine, tyrosine, and aspartate may hold promise as therapeutic targets for CD patients.
Momordica balsamina L.: A Plant with Multiple Therapeutic and Nutritional Potential. A Review
Authors: Thiaw Marème , Samb Issa , Genva Manon , Gaye Mohamed Lamine , Fauconnier Marie-Laure
Published: September 2023

Abstract: This comprehensive review seeks to deepen our comprehension of the African plant Momordica balsamina L. by elucidating its therapeutically important molecules and micronutrient composition. Commonly referred to as the balsam apple, this plant species is extensively harnessed for its diverse therapeutic potentials across its various organs including leaves, fruits, roots, and stems. Numerous bioactive molecules have been isolated or identified within this plant, notably encompassing polyphenols, flavonoids, terpenes, and carotenoids. These compounds exhibit a wide array of biological activities, ranging from antioxidative, anti-inflammatory, anti-diabetic, anti-carcinogenic, to anti-malarial properties, among others. Furthermore, the leaves of Momordica balsamina L. stand out for their abundant micronutrients, proteins, and amino acids. This investigation aims to shed light not only on the botanical characteristics of the Momordica balsamina plant and its potential applications in traditional medicine, but also on its chemical composition, biological functionalities, and physicochemical attributes, thus accentuating its nutritional advantages. Nonetheless, an intriguing avenue presents itself for the exploration of strategies to conserve this species, delve deeper into its potential within the cosmetics industry, and innovate methodologies for the synthesis or biosynthesis of these bioactive molecules.
Critical Review of Neural Network Generations and Models Design
Authors: Yousif Jabar H. , Yousif Mohammed J.
Published: September 2023

In recent years, Neural networks are increasingly deployed in various fields to learn complex patterns and make accurate predictions. However, designing an effective neural network model is a challenging task that requires careful consideration of various factors, including architecture, optimization method, and regularization technique. This paper aims to comprehensively overview the state-of-the-art artificial neural network (ANN) generation and highlight key challenges and opportunities in machine learning applications. It provides a critical analysis of current neural network model design methodologies, focusing on the strengths and weaknesses of different approaches. Also, it explores the use of different learning approaches, including convolutional neural networks (CNN), deep neural networks (DNN), and recurrent neural networks (RNN) in image recognition, natural language processing, and time series analysis. Besides, it discusses the benefits of choosing the ideal values for the different components of ANN, such as the number of Input/output layers, hidden layers number, activation function type, epochs number, and model type selection, which help improve the model performance and generalization. Furthermore, it identifies some common pitfalls and limitations of existing design methodologies, such as overfitting, lack of interpretability, and computational complexity. Finally, it proposes some directions for future research, such as developing more efficient and interpretable neural network architectures, improving the scalability of training algorithms, and exploring the potential of new paradigms, such as Spiking Neural Networks, quantum neural networks, and neuromorphic computing.
Controlled Case Report on the Surgical Treatment of Recurrent Rectal Cancer: The Role of the Minimally Invasive Approach
Authors: Izzo Paolo , Izzo Luciano , Cardi Maurizio , Polistena Andrea , Crocetti Daniele , Sibio Simone , Molle Marcello , De Intinis Claudia , Izzo Sara
Published: September 2023

(1) Background: The aim of this study is to investigate the diagnostic-therapeutic problem of pelvic recurrence of rectum cancer, highlighting current surgical standards and the possible role of the minimally invasive approach. This retrospective analysis of our surgical case study wishes to enter this debate while suggesting a possible line of action, based on the site of recurrence; (2) Methods: We examined, retrospectively, all the patients diagnosed, between 2008 and 2018, with cancer of the rectum at the "Pietro Valdoni" Department of Surgery and monitored their follow-up for 5 years. The sample consisted of 368 patients with rectal neoplasm, 136 females and 232 males, with an average age of 65.8 (ranging from 37 to 86); (3) Results: In 103 of the cases, the neoplasm was located in the upper rectum (28%), in 119 cases in the middle rectum (32.3%), in 102 cases in the lower rectum (27.7%), in 31 cases (8.4%) at the level of the right/sigma junction and in 13 cases it was not possible to define the site with certainty (3.5%); (4) Conclusions: The discussion re-mains open as to which approach is best at surgical level, whether laparoscopic, robotic or open-air. Our experience informs us that the most dangerous site remains on the anastomotic site.
Tomato Firmness and Shelf-Life Increased by Application of Stimulated Calcium
Authors: Dodgson Jolyon , Weston Anna K , Marks David J
Published: September 2023

Tomato (Solanum lycopersicum L.) has almost 190 million tonnes produced in 2023. Tomato fruit suffer losses of up to 50% during harvest and transport, which causes financial hardship, reduces the amount of food available and causes environmental harm. Calcium plays an important role in cell wall strength. This work assessed the use of a calcium transport stimulants (MCAS) to increase the firmness of tomato fruit in the laboratory and the foliar application to tomato plants. Then handling damage was simulated. In the laboratory, the calcium with MCAS significantly increased the fruit firmness compared to the untreated and calcium without MCAS, which were not significantly different. When calcium with MCAS was applied to tomato plants foliarly before harvest, the calcium with MCAS treated fruit were significantly firmer than the untreated or calcium without MCAS treated fruit for up to 10 weeks after harvest, and this was achieved by applying only 0.91 kg ha-1 calcium. Finally, when fruit were exposed to a simulated drop, the calcium with MCAS treated fruit remained firmer than the undamaged fruit or dropped fruit with calcium without MCAS. Calcium with MCAS could significantly increase the fruit firmness and increase the shelf-life of tomatoes while applying less calcium.
Preliminary Study on the Immunohistochemical Expression of Galectin-3 in Hypertrophic Hearts
Authors: Salzillo Cecilia , Giovannico Lorenzo , Fischetti Giuseppe , Cazzato Gerardo , Magistro Mario , Nucci Grazia , Serio Gabriella , Marzullo Andrea
Published: September 2023

Background: Galectin-3 (Gal-3) overexpression is associated with fibroblastic proliferation and the production of collagen, resulting in increased cardiac fibrosis and remodelling. Aim of the study was to investigate on the expression of Gal-3 in hypertrophic hearts. We examined 19 surgical specimens taken from interventricular septum of 8 patients with Tetralogy of Fallot, 4 patients with aortic valve stenosis, 1 cardiac explant affected from dilated cardiomyopathy, and 6 myocardial biopsies of patients submitted to heart transplantation. Methods: All the samples were routinely processed, stained with Hematoxylin-Eosin, Trichromic stain and elastic fiber stain and selected by having the morphological features of myocardial hy-pertrophy: myocytolysis, nuclear pleomorphism, interstitial fibrosis. Results: At immunohistochemistry, myocardial fibers showed cytoplasmic expression of Gal-3 in the 4 patients with aortic valve stenosis (diffuse in 3 and mild in 1), in the 1 patient with cardiac explant (mild) and in the 4/6 transplanted hearts (mild and focal in 3 and diffuse in 1). The 8 patients affected from Tetralogy of Fallot and 2 patients with transplanted hearts resulted negative. Conclusions: The results agreed with the hypothesis that Gal-3 may play a role in cardiac hyper-trophy; its expression in myocardial fibers is not related with the morphological aspects as suggested by the absence in pediatric cases. The presence in myocardial biopsies taken from transplanted hearts would suggest a possible role in predicting clinical outcome of such patients.
Vulnerability Assessment of Art Collections: the National Archaeological Museum “Gaio Cilnio Mecenate” in Arezzo (Italy)
Authors: Azzara Riccardo Mario , D'AMBRISI Angelo , Tanganelli Marco , Trovatelli Francesco , Vettori Nicoletta , Viti Stefania
Published: September 2023

Artworks play a fundamental role in the cultural and economic asset of communities, enforcing their identity and helping the social integration. Despite their importance, they are not always adequately protected against degradation, which can be induced by the aging, atmospheric and human-induced occurrence, and catastrophic events. Earthquakes certainly represent one of the main risks for art goods; however, traffic, construction works, and shipment can also represent a threat for art goods. Therefore, the assessment of the vulnerability of art collection to dynamic excitations plays a crucial role in their conservation, and it has been collecting an increasing attention by researchers, academics, and Museums’ managers. This work focuses on the vulnerability of the art collections exhibited at the Museum “Gaio Cilnio Mecenate” in Arezzo. Namely, it aims at assessing the effective dynamic loading experienced by the artworks, which is a function of the dynamic propagation plaid by the foundation soil, by the building and by the displayers used for exhibition. In this study the dynamic properties of some of the displayers used for exhibiting the art collections are investigated by performing an experimental survey. The analysis of the experimental data lead to assess the proper frequencies of the displayers, which have been compared to the ones of the building and the foundation soil of the Museum.
Cardiovascular Disease in Patients with Rheumatoid Arthritis (RA)
Authors: Rus Marius , Ardelean Adriana Ioana , Jurcau Ana Maria , Crisan Simina , Luca Constantin Tudor , Marian Paula , Pobirci Oana Lilliana , Huplea Veronica , Osiceanu Adrian Gheorghe , Osiceanu Alina Stanca , Guler Madalina Ioana , Andronie-Cioara Felicia Liana
Published: September 2023

The risk of developing cardiovascular diseases (CVD) in patients suffering from rheumatoid arthritis (RA) is 1.5 times higher compared to the general population. The objective of this retrospective study was to determine the type of cardiovascular complications that can appear in patients with rheumatoid arthritis. Reducing the cardiovascular risk, through an aggressive management of the traditional and non-traditional risk factors, is another objective of this study. Early diagnosis and initiation of therapeutic measures to reduce the progression rate of rheumatoid arthritis, while also maintaining an active lifestyle, are the most important problems in young patients.
We included a number of 200 patients with rheumatoid arthritis, presenting various stages of disease, concomitant with cardiovascular complications. The incidence by gender was higher in women, while men presented a higher incidence of traditional and non-traditional cardiovascular risk factors. All the patients presented an atherogenic coefficient over 2, indicating a significant risk of atherogenesis. An increased incidence of coronary artery disease was found in men. The patients presented cardiac arrhythmias, especially in the active stage of the condition, while the incidence of atrial fibrillation was higher in women. The active stage of the disease was evaluated using inflammatory biomarkers (ESR, PCR). ESR is not a specific tool for diagnosing the disease, but its important role in monitoring the activity of RA should not be ignored. Moreover, ESR has a significant role in monitoring the evolution and determining the prognostic of congestive heart failure.
A target treatment prescribed a target treatment to reduce inflammation and prevent exacerbations was prescribed for all patients.
However, in daily clinical practice, the screening for RA is poorly done. Thus, patients are often undiagnosed, while the risk factors are not assessed. In conclusion, even nowadays, RA patients continue to present an increased risk of developing CVD.
Short- and Medium-Term Electricity Consumption Forecasting Using Prophet and GRU
Authors: Son Namrye , Shin Yoonjeong
Published: September 2023

This study proposes a short- and medium-term electricity consumption prediction algorithm by combining the GRU model suitable for long-term forecasting and the Prophet model suitable for seasonality and event handling. (1) Manufacturing Company B's Electricity consumption data and meteorological data in Naju, Jeollanam-do, South Korea are collected and preprocessed. (2) The preprocessed data proposes the Prophet model in the first step for seasonality and event handling prediction. (3) In the second step, seven multivariate data are experimented with GRU. Specifically, the seven multivariate data consist of six meteorological data and the residuals between the predicted data from the proposed Prophet model in Step 1 and the observed data. These are utilized to predict electricity consumption at 15-minute intervals. (4) Electricity consumption is predicted for short-term (2 days and 7 days) and medium-term (15 days and 30 days) scenarios. The experimental results demonstrate that the proposed method outperforms the conventional Prophet model by more than 23 times and the modified GRU model by more than 2 times in terms of MAPE.
Tricyclic Graph with Minimum Randić Index
Authors: Tang Liangwen , Song Zhumei , Lin Mugang
Published: September 2023

The Randić index of a graph G is the sum of (dG(u)dG(v))−1/2 over all edges uv of G, where dG(u) denotes the degree of vertex u in G. In this paper, we investigate a few graph transformations that decrease Randić index of graph. By applying those transformations, we determine the minimum Randić index on tricyclic graphs, and characterize the corresponding extremal graphs.
Exploring Frailty in the Intersection of Cardiovascular Disease and Cancer in Older People
Authors: Amsalu Erkihun , Zhang Ying , Harrison Christopher , Nguyen Tan Van , Nguyen Tu Ngoc
Published: September 2023

Advances in cardiovascular therapies and cancer treatments result in longer patient survival. The coexistence of cancer and cardiovascular disease has been recognized as a complex clinical scenario. Beside cardiovascular disease, older people with cancer are at greater risk of experiencing multimorbidity and the geriatric syndromes such as frailty. In older people, the concurrent presence of cancer and cardiovascular disease increased the risk of mortality, and the presence of frailty can exacerbate their conditions and hinder the treatment effectiveness. Given the significant intersection among frailty, cardiovascular disease and cancer in older people, this paper aims to provide an overview of the current research in this field and identifies gaps in research to understand the burden and impact of frailty in these populations. While many studies have examined the prevalence and impact of frailty on adverse outcomes in patients with cancer or with cardiovascular disease, evidence of frailty in individuals with both conditions is lacking. There is no universally accepted definition of frailty, which leads to inconsistencies in identifying and measuring frailty in older adults with cardiovascular disease and cancer. The frailty index seems to be a preferred frailty definition in studies in patients with cancer, while the frailty phenotype seems to be more commonly used in cardiovascular research. However, differences in how the frailty index was categorised and in how patients were classified as ‘frail’ depending on the cut points may have negative effect on understanding the impact of frailty in the studied populations. This makes it challenging to compare findings across different studies and limits our understanding of the prevalence and impact of frailty in these populations. Addressing these research gaps will contribute to our understanding of the burden of frailty in older people with cardiovascular disease and cancer, and improved clinical care protocols in this vulnerable population.
Gestalt’s Perspective on Insight, a Recap Based on Recent Behavioral and Neuroscientific Evidence.
Authors: Vitello Mary , Salvi Carola
Published: September 2023

The Gestalt psychologists’ theory of insight problem-solving was based on a direct parallelism between perceptual experience and higher-order forms of cognition (e.g., problem-solving). Simi-larly to the sudden recognition of an ambiguous figure, they contended that problem-solving in-volves a restructuring of one's initial representation of the problem’s elements, leading to a sud-den leap of understanding phenomenologically indexed by the "Aha!" feeling. Over the last centu-ry, different scholars discussed the validity of the Gestalt psychologists’ perspective foremost us-ing the behavioral measures available at the time. However, in the last 2 decades, scientists gained a deeper understanding of insight problem-solving due to the advancements in cognitive neuroscience. This review aims to provide a retrospective reading of Gestalt theory based on the knowledge accrued by adopting novel paradigms and investigating their neurophysiological correlates. Among several key points that the Gestalt psychologists underscored, we focus specif-ically on the role of the visual system in marking a discrete switch of knowledge into awareness, as well as the perceptual experience and the holistic standpoints. While the main goal of this paper is to read the previous theory in light of new evidence, we also hope to initiate an academic dis-cussion and encourage further research about the points we raise.
Specialty Care and Counselling about Hereditary Cancer Risk Improves Adherence to Cancer Screening and Prevention in Newfoundland and Labrador Patients with BRCA1/2 Pathogenic Variants: A Population-Based Retrospective Cohort Study
Authors: Roebathan Aimee , Smith Kerri , Seal Melanie , Etchegary Holly , Dawson Lesa
Published: September 2023

BRCA1 and 2 pathogenic variants increase lifetime risks of breast (50-75%) and ovarian cancer (15-20%). Guidelines recommend breast screening (MRI and mammogram) or risk-reducing mastectomy with salpingo-oophorectomy for ovarian cancer prevention. We sought to 1) characterize the population of BRCA1/2 carriers in Newfoundland and Labrador (NL) 2) evaluate risk-reducing interventions 3) identify factors influencing screening and prevention adherence.
Methods: This is a retrospective study from a population-based provincial cohort of BRCA1/2 carriers. Eligibility criteria for risk-reducing interventions were defined for each case and patients were categorized based on their level of adherence with recommended screening or prevention. Chi-squared and regression analyses were used to determine which factors influenced uptake and level of adherence.
Results: 276 BRCA1/2 carriers were identified; 156 living NL females composed the study population. Unaffected females were younger at testing than those with a cancer diagnosis (44.4 y versus 51.7 y; p=0.002). Categorized by eligibility, 61.0%, 61.6%, 39.0% and 75.7% of patients underwent MRI, mammogram, risk-reducing mastectomy, and risk-reducing salpingo-oophorectomy, respectively. Individuals with breast cancer were more likely to have risk-reducing mastectomy (64.7% versus 35.3%; p<0.001), and those who attended specialty hereditary cancer clinic were more likely to be adherent with breast/ovarian cancer recommendations (73.2% versus 13.4%; p<0.001) and to undergo risk-reducing salpingo-oophorectomy(84.1% versus 15.9%; p<0.001).
Conclusions: Nearly 40% of female BRCA1/2 carriers were not receiving breast surveillance according to evidence-based recommendations. Cancer risk reduction and uptake of breast imaging and prophylactic breast and pelvic surgeries are significantly higher in patients who receive dedicated specialty care. Organized hereditary cancer prevention programs will be a valuable component of Canadian health care systems and have the potential to reduce the burden of disease country-wide.
Occurrence of Anthracnose Caused by Colletotrichum gloeosporioides on Lucky Bamboo in China
Authors: Xiong Qin , Zhang Yaxin , Wang Xueying , Qian Yulin , Wu Wei , Li Jinwen , Zeng Qirui
Published: September 2023

Lucky bamboo (Dracaena sanderiana hort. ex Mast. = Dracaena braunii) is a domestic species widely cultivated for ornamental purposes in China. In March 2022, a severe occurrence of anthracnose disease was observed on the stems of lucky bamboo plants in a greenery retail store located in Nanjing, Jiangsu Province, China. The morphological characteristics of isolates obtained from diseased stem tissues were identical with those described for Colletotrichum species. Based on multilocus phylogenetic analysis with the internal transcribed spacer (ITS), actin (ACT) gene, and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) gene, the pathogen was identified as Colleto-trichum gloeosporioides (Penz.) Penz. & Sacc. Pathogenicity was verified by mycelial plug-inoculating stem cuttings of one-year-old lucky bamboo plants and spray-inoculating whole one-year-old lucky bamboo plants, respectively. Koch’s postulates were fulfilled by the re-isolation of C. gloeosporioides from symptomatic tissues. To the best of our knowledge, this report describes the first time that C. gloeosporioides was observed to cause anthracnose on lucky bamboo in China.
Numerical Modelling of the Geotechnical and Structural Strengthening of Quay Structures with a Case Sudy
Authors: Bildik Selçuk
Published: September 2023

In recent years, with the increase in maritime trade, the necessity of increasing the capacities of the ports has emerged. However, while it is planned to increase the capacities of the ports, it is important that the port continues to operate at the same time. In this respect, the old port structures should not be damaged during the capacity increase. In this study, the strengthening of a port in Guinea is discussed as a case study. In the study, the existing quay wall was evaluated, and geotechnical and structural alternatives of the new structure to be built for capacity increase were evaluated. A combined system was designed as a pile foundation and a reinforced foundation with plastic piles so as not to damage the existing quay wall. The pile capacities obtained as a result of the analyses were verified by loading tests.
Implementation of Intelligent Physical Exercise Training at a Danish Hospital—A Qualitative Study of Employees’ Barriers and Facilitators for Participation
Authors: Pultz Christina Juul , Lohse Thea Mundt , Justesen Just Bendix , Særvoll Charlotte Ahlgren , Møller Sofie Fønsskov , Lindegaard Birgitte , Fischer Thea Kølsen , Dalager Tina , Molsted Stig
Published: September 2023

Abstract: Background: Exercise Training at work has the potential to improve employees’ produc-tivity, health, and well-being. However, exercise interventions to healthcare workers in hospitals may be challenged by a high time pressure and the ongoing workflow with patient care. Objective: The aim was to identify barriers and facilitators for participation in exercise training during work in a hospital department. Methods: Eight semi-structured interviews were conducted with hospital employees of different staff groups, who participated in 12 weeks exercise twice weekly. The data analysis was a thematic approach based on the Theoretical Domains Framework and the COM-B factors in the Behavior Change Wheel. Results: Barriers and facilitators varied between different groups. Barriers included limited structure, busyness, and a discouraging culture. Facilitators in-cluded gaining a feeling of community, psychological and physical well-being. Seven contextual subthemes were vital for successful implementation of exercise in a hospital setting. Conclusions: The informants appreciated exercise training during work and wished to participate. Inpatient departments’ informants had difficulties participating in the intervention, whilst those with more administrative tasks found it easier. This study identified barriers and facilitators vital for a successful implementation of an exercise training intervention in a hospital department to improve health, wellbeing, and productivity amongst hospital employees. It explains how future interventions can improve reach, adoption, and implementation of exercise training interventions for hospital staff.
Anisotropic Fractional Cosmology: K-Essence Theory
Authors: Socorro J. , Rosales J Juan , Sesma L Toledo
Published: September 2023

In the particular configuration of the scalar field K-essence in the Wheeler-DeWitt quantum equation, for some age in the Bianchi type I anisotropic cosmological model, a fractional differential equation
for the scalar field arises naturally. The order of the fractional differential equation is $\beta=\frac{2\alpha}{2\alpha - 1}$. This fractional equation belongs to different intervals, depending on the value of the barotropic parameter; when $\omega_{X} \in [0,1]$, the order belongs to the interval $1\leq \beta \leq 2$, and when $\omega_{X}\in[-1,0)$, the order belongs to the interval $0<\beta \leq 1$. In the quantum scheme, we introduce the factor ordering problem in the variables $(\Omega,\phi)$ and its corresponding momenta $(\Pi_\Omega, \Pi_\phi)$, obtaining a linear fractional differential equation with variable coefficients in the scalar field equation, then the solution is found using a fractional power series expansion. The corresponding quantum solutions are also
given. We found the classical solution in the usual gauge N obtained in the Hamiltonian formalism and without a gauge. In the last case, the general solution is presented in a transformed time $T(\tau)$,
however in the dust era we found a closed solution in the gauge time $\tau$.