bluuebunny/crossref_metadata_2025 huggingface dataset:
A Rare Side Effect of Ibrutinib: Tumor Lysis Syndrome
Authors: Öztürk Erman , Erdoğan Özünal Işıl
Published: June 2021

Chronic lymphocytic leukemia (CLL) is a progressive disease with an indolent course, and tumor lysis syndrome (TLS) is rarely seen in CLL. Ibrutinib is a novel bruton kinase (BTK) inhibitor increasingly used in CLL treatment. Ibrutinib has significant side effects such as atrial fibrillation, bleeding, diarrhea, and infections. However, TLS is reported rarely with ibrutinib treatment. This report focuses on a 69-year-old female patient diagnosed with relapsed CLL who developed grade 4 TLS after ibrutinib monotherapy. The patient developed TLS on the third day of ibrutinib treatment necessitating discontinuation of the treatment and initiation of hemodialysis and supportive care. Ibrutinib treatment was re-initiated at a daily dose of 140 mg therapy after an interval of seven days, and then any additional side effect was not seen. Tumor lysis syndrome secondary to ibrutinib has been reported in an increasing number of cases. There is currently no information on managing adverse effects of TLS attributed to ibrutinib. Consequently, ibrutinib treatment of this patient was not terminated, and restarted after a short interval. It must not be forgotten that TLS secondary to ibrutinib treatment may be rarely seen, and can be life-threatening. Treatment with ibrutinib should be initiated in consideration of this side effect, and the development of complication of TLS may not necessitate discontinuation of ibrutinib treatment.
Biofilm Formation and Antimicrobial Susceptibility of Non-Diphtheriae Corynebacterium Strains Isolated from Blood Cultures: First Report from Turkey
Authors: Özdemir Sinem , Aydoğan Okan , Köksal Çınar Fatma
Published: June 2021

Objective: Non-diphtheriae Corynebacterium strains have been recognized as important pathogens after decades of confusion regarding their microbiological classification and clinical significance. The aim of this study was to identify non-diphtheriae Corynebacterium strains and the prevalence of biofilm formation and antimicrobial resistance. Method: In total, 126 non-diphtheriae Corynebacterium strains were isolated from blood cultures of inpatients with bacteremia in our hospital between January 2015 and January 2020. Blood cultures were analyzed with the Bactec-9120 system. Strains were identified using MALDI-TOF MS (Bruker Daltonics, Germany). Antimicrobial susceptibilities were determined using the Kirby-Bauer disk diffusion method on a Mueller-Hinton agar and evaluated according to EUCAST standards. Biofilm formation was assessed with the Congo Red Agar method. Results: Corynebacterium striatum and Corynebacterium matruchotii were the most prevalent with 29 and 26 isolates, respectively. Biofilm production was detected in 62.06% (18/29) of C. striatum, in 53.8% (14/26) of C. matruchotii, in 50% (9/18) of Corynebacterium afermentans, 50% (6/12) of Corynebacterium amycolatum, and in 46% (7/15) of Corynebacterium jeikeium strains. Among the five most prevalent strains, we found a high biofilm rate of 54%. The resistance rates to penicillin, clindamycin, ciprofloxacin, rifampicin, tetracycline, and gentamicin were 91.2%, 87.3%, 79.3%, 56.3%, 45.2%, and 39.6%, respectively. All 126 strains were susceptible to vancomycin and linezolid. Conclusion: Non-diphtheriae Corynebacterium strains isolated from blood cultures of hospitalized patients with bacteremia may have multidrug resistance and the ability to produce biofilm. These results emphasize the importance of identifying strains and determining their antimicrobial susceptibility and biofilm production potential.
AGROINDUSTRIAL COMPLEX OF MOLDOVA IN THE CONTEXT OF ENSURING FOOD SECURITY
Authors:   Academy of Public Administration, Republic of Moldova, Sacovici Vasilii
Published: June 2021

The article examines the state of food security in the Republic of Moldova and the provision of the country’s population with food since the last quarter of the XX century. Until now. Based on the analysis of various information for the specified period, the author showed that by the end of the XX century. due to the destruction of the main production potential of the agro-industrial complex, Moldova lost its food independence. On the one hand, this is the result of a significant decline in domestic food production. On the other hand, this trend is explained by a sharp increase in imports of traditionally produced in the country types of food products. In conclusion, it is concluded that ensuring food security in Moldova is possible on its own production basis, which is due to significant natural resources sufficient for the production of all major types of food products in the required quantity and proper quality. Due to the fact that in modern conditions agricultural production and food markets, being neither self-regulating nor self-sufficient, cannot successfully function without state regulation and support The government should take responsibility for the development and implementation of a specific state program in the field of national security in the food sector to provide the population with its own food. Keywords: agro-industrial complex, Moldova, food security, reform, physical accessibility, development strategy.
Decreasing the Tendency of Water to Form Scale and Corrosion in Cooling Towers – South Refineries Company (SRC) – Iraq
Authors: Abbas Thabit , Muthna Qays , Shihab Thikra , Jabur Ola
Published: June 2021

Scale formation and corrosion phenomena are major technical problems at Basra Refinery/ South Refineries Company (SRC). These technical problems are concentrated in cooling towers which are used to supply cooling water to the processing units. The Scales and corrosion products precipitate inside cooling units, heat exchangers and pipeline networks affecting negatively efficiency of refinery’s equipment. In this work, a real plant data was collected from four cooling towers which is supplied the coolant to the crude distillation units of the refinery and also from the raw water supplier. The collected data was fitted by Langelier model to predict the tendency of cooling water for scale forming and activation of corrosion. The obtained result shows that the cooling water has a tendency to form scale (CaCO3 Precipitation) at cooling tower units. Also the feed water has the same tendency for scale forming.After analyzing the LSI (Langelier Saturation Index) results, the research team recommends the particular company to overcome this problem by installing a Reverse Osmosis (RO) plant for treating raw water to decrease the concentrations of total dissolved solids (TDS) which result scale and corrosion in the parts of cooling tower as an option to solve the problem.
The Influence of Glass Fiber and Milled Glass Fiber on the Performance of Iraqi Oil Well Cement
Authors: Assi Amel Habeeb , Almahdawi Faleh H. M. , Khalti Qasim Abdulridha
Published: June 2021

The reinforced fiberglass in cement slurry reflects the effect on its properties compared to usual additives. Fiberglass is typically used in cement slurry design for one or another of the following goals: (Earth earthquake, bearing storage, and with differential stresses, to enhance cement durability and increase its compressive strength). The main goal is to use glass fiber and ground fiberglass to improve the tensile strength and moderate compressive strength significantly. On the other hand, the use of glass fibers led to a slight increase in the value of thickening time, which is a desirable effect. Eleven glass fiber samples and milled glass fiber were used to show these materials' effect on Iraqi cement with (0.125, 0.25, 0.5, 0.75, 1, and 2) % of cement weight. Those tests used to study cement slurry‟s following properties were compressive strength, thickening time, rheology properties of free water, filtering, and density. These evaluations showed that slurries with less than 1% fiber content gave a higher compressive strength than a sample containing more than 1% glass fiber. However, the slurry mixed with equal or less than 1% milled glass fiber is higher compressive than the sample mixed with more than 1% milled glass fiber. So the optimal concentration for glass fiber is less than 1% by weight of cement (BWOC); either for milled glass fiber, it is less or equal to 1% BWOC. Both materials contributed to increasing the compressive strength of the cement. However, attention must be paid to the idealThis work is licensed under a Creative Commons Attribution 4.0 International License.

concentration that should be added during the cement slurry preparation because if we use these two materials carelessly for the ideal concentration, this leads to the collapse and bombardment of the resistance of the cement rock. In other words, the collapse of cement resistance and causing problems during the cementing process.
Trends in TC/HDL and LDL/HDL Ratios across the Age Span: Data from the 2007-2018 National Health and Nutrition Examination Survey (NHANES)
Authors: Wang Inga , Kapellush Jay , Hou Stephen , Rahman Mohammad H , Li Xiaoyan , Ritchie David
Published: June 2021

Background. Cholesterol levels in total cholesterol (TC), low-density lipoprotein (LDL-C), high-density lipoprotein (HDL-C), and triglyceride (TG) contribute to atherosclerosis and its clinical consequences. Objectives. This study aimed to examine the trends in serum TC/HDL and LDL/HDL ratio across the age span. Methods. This is an observational study. Blood lipid measurements, taken from 85,646 noninstitutionalized participants, aged 6 to 80, were obtained from the National Health and Nutrition Examination Survey (NHANES) study. We compared the TC/HDL and LDL/HDL ratio trends in three distinct cross-sectional surveys during 2007-2010, 2011-2014, and 2015- 2018. Results. Cholesterol ratios changed by age and differed by sex. Mean TC/HDL ratios declined from 4.03 (95% CI, 4.01-4.05) in 2007-2010, to 3.84 (95% CI, 3.81-3.87) in 2015-2018 (p<.05 for linear trend) in male; mean TC/HDL ratios declined from 3.69 (95% CI, 3.67-3.70) in 2007- 2010, to 3.45 (95% CI, 3.42-3.47) in 2015-2018 (p<.05 for linear trend) in female. Mean LDL/HDL ratios declined from 2.30 (95% CI, 2.28-2.32) in 2007-2010, to 2.18 (95% CI, 2.15- 2.20) in 2015-2018 (p<.05 for linear trend) in male; mean LDL/HDL ratios declined from 2.04 (95% CI, 2.02-2.06) in 2007-2010, to 1.96 (95% CI, 1.94-1.98) in 2015-2018 (p<.001 for linear trend) in female. Conclusions. Between 2007 and 2018, favorable trends in lipid ratio levels were observed among noninstitutionalized residents in the US.
OCORRÊNCIA DE BRUXISMO EM CRIANÇAS ACOMPANHADAS POR 12 ANOS NASCIDAS NAS DÉCADAS DE 80, 90 E 2000
Authors: Rédua Renato Barcellos , Rédua Paulo César Barbosa , Lira Adriana de Oliveira
Published: June 2021

Entre as parafunções orais, o bruxismo aparece como o mais frequente, juntamente com o hábito de sucção de chupeta, em crianças brasileiras. Esta é uma condição clínica indesejável que pode resultar em danos às estruturas dentárias. Segundo a literatura sua prevalência gira em torno de 7 a 20% nas crianças, assim o odontopediatra deve estar atento a diagnosticar e proporcionar uma abordagem eficiente para o controle do bruxismo. O objetivo deste trabalho foi verificar a ocorrência do bruxismo em crianças acompanhadas desde o primeiro ano de vida até os 12 anos, nas décadas de 80, 90 e 2000; e verificar a idade de maior incidência desta alteração. Metodologia: Um estudo coorte composto por 600 prontuários de crianças que foram acompanhadas da idade de 12 a 23 meses até completar 12 anos de idade, em um consultório particular, sendo 200 crianças na década de 80 (Grupo 1), 200 de 90 (Grupo 2) e 200 na década de 2000 (Grupo 3). Resultados: Das 600 crianças avaliadas, 100 (16,6%) foram diagnosticadas com bruxismo, sendo 26 dessas acompanhadas na década de 80 (13%), 33 na década de 90 (16,5%) e 41 na década de 2000 (20,5%). 30 crianças (30%) delas receberam o diagnóstico do 1º. ao 4º. ano de vida, 55 (55%) do 5º ao 8º ano e 15 (15%) do 9º ao 12º ano. Conclusões: Verificou-se aumento do diagnóstico de bruxismo em crianças ao longo das décadas, e a incidência desta alteração foi maior em crianças de 5 a 8 anos de idade.
CAPITAL SOCIAL ENTRE OS ATINGIDOS POR HIDRELÉTRICAS NO SUL DO BRASIL
Authors: Tabares Camila de Vasconcelos , González Rodrigo Stumpf
Published: June 2021

O processo de implantação de Usinas Hidrelétricas de Energia atinge milhares de pessoas afetando o desenvolvimento da vida social, política e comunitária. Em 1979 a região da bacia do rio Uruguai foi considerada estratégica para implantação de hidrelétricas o que desencadeou em diversas mobilizações políticas das comunidades atingidas. Baseando-se na teoria do Capital Social este trabalho busca avaliar a associação entre os indicadores de confiança institucional e interpessoal com a participação política dessa população. Para isso, utiliza-se os dados coletados pelo Projeto de Pesquisa e Desenvolvimento “Avaliação dos Resultados e Proposição de Modelo de Elaboração de Programas de Remanejamento da População Atingida por Empreendimentos Hidrelétricos (2010-2014)”. Conclui-se que os componentes de confiança institucional e de confiança interpessoal, referentes ao capital social na teoria de Putnam, não estão associados à participação política nessa população, pois as mobilizações desencadeadas pelos remanejamentos levaram a resultados pontuais e sem transformações em uma cultura política participativa.
A ARMADILHA DA DEMOCRACIA DIRETA: UMA ANÁLISE QUALITATIVA DOS PODERES LEGISLATIVOS DO PRESIDENTE NA AMÉRICA DO SUL
Authors: Barros Ana Tereza Duarte Lima de
Published: June 2021

Como instrumentos da democracia direta estariam associados a um menor nível de democracia? Venezuela, Bolívia e Equador promulgaram novas constituições que previram a ampla incorporação de instrumentos da democracia direta. O presente trabalho propõe que o referendo, quando convocado pelo presidente, serve para que o líder possa apelar diretamente às massas, sem qualquer intermediação legislativa, uma das principais características do populismo. Através da ferramenta Qualitative Comparative Analysis – QCA é feita uma análise qualitativa dos poderes legislativos do presidente na América do Sul. Conclui-se que o poder presidencial de convocar referendos está associado a um menor nível democrático. Dia 30 de novembro de 2008, utilizando-se do poder de referendo, o então presidente da Venezuela Hugo Chávez, convocou os cidadãos para decidirem a respeito da possibilidade de reeleição por tempo indefinido para o cargo de chefe do Executivo. Dia 15 de fevereiro de 2009, com 54,86% dos votos a favor e 45,1% contra, Chávez conseguiu aprovar a reforma constitucional que habilitou a reeleição de maneira indefinida.
POLÍCIA FEDERAL, CONTROLE MIGRATÓRIO E LIVRE CIRCULAÇÃO DE CIDADÃOS DO MERCOSUL
Authors: Kyosen Renato Obikawa
Published: June 2021

No passado, a Polícia Federal do Brasil atuou como instrumento de repressão política. Forjada e desenvolvida em contextos autoritários, caracterizada por um autarquismo e desconfiança generalizada, seria possível indagar se a Polícia Federal brasileira teria algum protagonismo nos fins sociais visados pelo Mercosul. Como projeto de integração sul-americana, não apenas econômica, mas também cultural e social, o Mercosul almeja que seja implementada uma política de livre circulação de pessoas na sua região. Como órgão de persecução criminal, a Polícia Federal costuma submeter os cidadãos estrangeiros, como um todo, a um regime de suspeição. No entanto, diante das tratativas regionais firmadas para viabilizar uma livre circulação no espaço mercosulino, seria possível analisar se a atuação da Polícia Federal brasileira auxiliaria na consecução desse ensejo regional de suma relevância para a integração desejada.
O ÊXODO ÁRABE E A CRISE HUMANITÁRIA NA EUROPA: UMA ANÁLISE DE SUAS AMBIVALÊNCIAS POLÍTICAS
Authors: Silva Daniella Motta da
Published: June 2021

Nos últimos anos as solicitações de asilo na União Europeia se multiplicaram. Centenas de refugiados fugiram rumo ao continente, resultado, principalmente, da guerra civil que se instaurou na Síria. Até o mês de julho de 2015, segundo a Eurostat, aproximadamente 438 mil refugiados entraram com o pedido de asilo nos países do bloco europeu. Dito isto, este trabalho tem por objetivo analisar tal conjuntura desafiadora pela qual a União Europeia se viu confrontada, diante da absorção em massa de refugiados, majoritariamente de origem muçulmana, advindos, em especial, do conflito na Síria. Assim, tal questão será analisada sob a ótica da securitização da imigração e da segurança societal. Buscando auxiliar na compreensão da formação da delicada conjuntura de crise humanitária que se instaurou nos países do bloco europeu, após a chegada, em quantidades alarmantes, de refugiados às fronteiras europeias.
VULNERABILIDADE DA FLORA ÚNICA DO ESPINHAÇO MINEIRO
Authors: Silva Patricia Köster e , Pivello Vânia Regina
Published: June 2021

Fatores de ameaça são perturbações que tornam as espécies vulneráveis à extinção em seus habitats naturais. A proposição de ações conservacionistas à biodiversidade requer o conhecimento das ameaças às espécies em questão. O Espinhaço mineiro é reconhecido por sua biodiversidade florística e alto endemismo e, a ocupação humana ocorre devido à mineração histórica de ouro e diamantes. Após o declínio das minas, o extrativismo de sempre-vivas, turismo, agropecuária e expansão urbana são vetores de destruição aos ambientes naturais, levando à hipótese de que ambientes que conservam intacta parte dessa rica biodiversidade, podem estar gravemente ameaçados. Logo, objetivamos avaliar o estado de conservação do Espinhaço mineiro, identificando as principais ameaças às espécies-alvo, micro endêmicas ameaçadas, que são lacunas em conservação, por não estarem protegidas. Fizemos uma revisão sistemática para identificar as ameaças na região e, utilizando imagens remotas, analisamos o uso das terras em série temporal. Para identificar quais fatores pressionam a flora da região, aplicamos aos sete sítios prioritários, dois índices de vulnerabilidade, analisando ameaças primárias (perda de habitat), secundárias (erosão da biodiversidade) e a representatividade das espécies-alvo, em unidades de conservação. Os resultados indicaram que os sítios mais ameaçados são pressionados por ameaças secundárias e, 91% das espécies-alvo são lacunas em conservação. As prioridades em conservação são os sítios Serra do Cipó, Diamantina e Águas Vertentes, também apresentando piora no risco de extinção das espécies-alvo. Os sítios prioritários representam 83% da flora ameaçada na região, sendo necessárias medidas urgentes, como a criação de unidades de conservação nas áreas mais vulneráveis.
EFEITOS DA APLICAÇÃO DE BIOSSÓLIDO E RESÍDUOS DE PODA NA REVEGETAÇÃO DE ÁREA DE EMPRÉSTIMO NO DISTRITO FEDERAL
Authors: Fraga Leonardo Pereira , Santos Thauany Pires dos , Schmidt Isabel Belloni
Published: June 2021

Em regiões urbanas e periurbanas, as áreas de empréstimo representam um exemplo comum de áreas degradadas. Nas cidades também são frequentes os problemas de destinação dos resíduos sólidos. O lodo de esgoto estabilizado (biossólido) e os resíduos da poda vegetal constituem um substrato promissor no desenvolvimento de espécies arbóreas em áreas degradadas. O presente trabalho avaliou sobrevivência e crescimento inicial de mudas de espécies florestais e savânicas do Cerrado, em tratamentos com diferentes dosagens de lodo e de resíduos de poda, em área de empréstimo. O delineamento experimental foi em blocos casualizados com nove tratamentos e três repetições, totalizando 27 parcelas. Foram testados os efeitos de três níveis (doses) dos dois fatores (Lodo - L e Poda - P): L0P0 (controle); L0P1 (122,5 Mg.ha-1 de poda); L0P2 (245 Mg.ha-1 de poda); L1P0 (270 m3 .ha-1 de lodo); L1P1; L1P2; L2P0 (1.080 m3 .ha-1 de lodo); L2P1; e L2P2. Em cada parcela foram plantadas 60 mudas (seis por espécie) das 10 espécies testadas. A maioria das espécies florestais (Anadenanthera colubrina, Copaifera langsdorffii, Peltophorum dubium, Senegalia polyphylla, Schinus terebinthifolius, Sterculia striata e Tabebuia impetiginosa) apresentou alto percentual de sobrevivência e relativo crescimento nos tratamentos com dosagens combinadas dos resíduos ou com dosagens de lodo. Espécies savânicas (Alibertia edulis, Alibertia sessilis e Tabebuia aurea) apresentaram pouco crescimento nos tratamentos testados. T. aurea apresentou o menor percentual de sobrevivência no experimento. O uso de espécies florestais do Cerrado para revegetação de área de empréstimo urbana, em tratamentos com biossólido e resíduos de poda, apresentou resultados satisfatórios.
UM OLHAR SOBRE A EDUCAÇÃO DE SURDOS NO BRASIL: SILENCIANDO VOZES NO SISTEMA DE ENSINO
Authors: Silva Flavia Oliveira Teófilo da
Published: June 2021

Este capítulo promove o debate sobre os temas que envolvem a educação de surdos brasileira, desde sua concepção ao longo da história até a abordagem política e legislativa em torno desse universo de ensino. Para completar essa discussão, destacam-se os aspectos em que se baseiam as propostas educativas bilíngues destinadas à comunidade surda e, brevemente, quais são as lacunas por trás da formação do professor de Educação Básica que, em algum momento de sua carreira, possivelmente terá de lidar com o aluno surdo em classes de ensino regular. O objetivo é contribuir para o conhecimento de questões referentes à educação de surdos que circulam em documentos oficiais e na legislação, a partir de uma análise linguística e histórica de discursos pautados nas concepções de aprendizagem de línguas que emanam desses documentos e dessas leis. Na tentativa de aproximar-se de seus coenunciadores, os enunciados presentes no interior de tais escritos, que tematizam, supostamente, o ensino de português como segunda língua (L2) para alunos surdos, além de prescreverem a atividade docente, apagam as subjetividades dos alunos com surdez, desconsiderando suas particularidades e silenciando suas vozes como verdadeiros protagonistas desse sistema de ensino.
A MATÉRIA PRIMA E O PROCESSO CRIATIVO EM UM ESPAÇO DE FAZER SABERES
Authors: Saturnino Joice
Published: June 2021

Este artigo tem o objetivo de registrar e mostrar um caminho de construção e possibilidades da criação em arte a partir da matéria prima, tendo como fundo um processo artístico-pedagógico, onde o resultado final se sintetiza no Objeto-Arte. Uma busca que passa pelas práticas tradicionais vindas de conhecimentos seculares adquiridas das “Pessoas Livros”, personagens encontradas na caminhada, e por arquivos de imagens e informações formados pelo tempo em espaços vivenciados cheios de importância e fertilidade. Uma recuperação e apropriação do saber tradicional que passa a fazer parte do processo criativo onde a busca pela troca de experiências é o ponto fundamental. Faço uso da função simbólica de testemunhar e arquivar conversas, plantas, desenhos, relevos e pessoas. Enveredo pelo caminho das informações e da matéria-prima sempre lembrando da importância da construção do objeto-arte, como parte fundamental de um trabalho onde a arte é a principal razão.
UTILIZAÇÃO DE FUNGOS O TRATAMENTO DE EFLUENTES TÊXTEIS: UMA REVISÃO NARRATIVA
Authors: Silva Amanda Tayara Ribeiro da , Sacramento Patrícia Almeida , Battistelli André Aguiar
Published: June 2021

A indústria têxtil se destaca por seu desempenho econômico, devido a sua capacidade de produção e geração de empregos. Com a expansão de suas atividades, amplia-se o uso de matéria-prima e água, gerando grandes quantidades de resíduos sólidos e efluentes líquidos em toda sua rede de produção, sendo um fator de grande importância no que diz respeito à contaminação ambiental. Os efluentes resultantes da etapa de tingimento são mais problemáticos devido à elevada carga de compostos químicos dos corantes. Nesse viés, processos físicos e químicos são alternativas para o tratamento destes efluentes, porém tratamentos biológicos vêm se destacando por ser um processo natural, em que não há necessidade de adição de substâncias químicas no processo. Nesse contexto, o presente estudo teve por objetivo realizar uma discussão acerca da utilização de fungos para o tratamento de efluentes têxteis, com ênfase no potencial de biodegradação enzimática de corantes, nas condições operacionais utilizadas durante o tratamento e em sua aplicabilidade prática. Para tanto, realizou-se uma revisão bibliográfica do tipo narrativa com foco no objeto de estudo. A partir do levantamento realizado, constatou-se que a utilização de fungos para o tratamento de efluentes têxteis apresenta elevada potencialidade, principalmente devido a sua capacidade de biodegradação enzimática de corantes, aliada ao processo de adsorção. Já com relação às condições operacionais utilizadas, a concentração de fungos (ou substrato) é o fator de maior influência. Estudos mais aprofundados devem ser realizados a fim de determinar as condições ótimas do processo, podendo viabilizar a sua aplicabilidade em larga escala.
RESÍDUOS SÓLIDOS URBANOS EM MACHADINHO D’OESTE-RO: PROPOSTA DE GESTÃO AMBIENTAL
Authors: Miguel Nathalia Gallizzi , Camilo Rodrigo , Miranda Yara Campos
Published: June 2021

Com a crescente inovação tecnológica, os produtos tornaram-se cada vez mais descartáveis, e juntamente com o padrão de consumo humano atual destaca-se a problemática da geração de resíduos sólidos urbanos, que são aspectos ambientais responsáveis por ocasionar impactos na qualidade do solo, água e ar. Nesse sentido, o presente trabalho, caracterizado como estudo de caso, buscou realizar um diagnóstico da gestão dos resíduos sólidos urbanos do município de Machadinho D’Oeste, localizado em Rondônia, visando propor melhorias em tal processo. Para tanto, a primeira etapa consistiu no levantamento de dados pertinentes ao percentual coletado e destinado no município por meio de entrevistas e consulta a órgãos públicos e demais documentos relevantes a temática. A partir da obtenção de tais dados, realizou-se uma análise que resultou no diagnóstico da gestão de resíduos sólidos urbanos da área de estudo. Por fim, apresentou-se medidas para adequação do município. Os resultados demonstraram que Machadinho D’Oeste não possui uma gestão de resíduos sólidos implementada, necessitando assim de ajustes de acordo com a legislação ambiental, seguindo as diretrizes da Política Nacional de Resíduos Sólidos, assegurando assim, a qualidade do meio ambiente e uma adequada utilização dos recursos naturais.
Responding to emerging needs: Development of adapted performance indicators for physiotherapy student assessment in telehealth
Authors: Nahon Irmina , Jeffery Lauren , Peiris Casey , Dunwoodie Ruth , Corrigan Rosemary , Francis-Cracknell Alison
Published: June 2021

Clinical placements in 2020 have been significantly impacted by the COVID-19 global pandemic. Ensuring that effective clinical placement opportunities continue during this time remains the priority of the Clinical Education Managers Australia and New Zealand (CEMANZ). Supporting educators to assess student competency when service delivery models are altered to embrace telehealth services, has been integral to achieving this.

Telehealth has been widely adopted to maintain services and contact with patients during the pandemic. Physiotherapy clinical educators voiced concern about the applicability of the Assessment of Physiotherapy Practice (APP) tool in this emerging learning environment and sought guidance from University Clinical Education Managers. This paper describes representative consensus across Universities regarding use of the Assessment of Physiotherapy Practice (APP) tool and the development of adapted APP performance indicators for use in telehealth. Clinical educators can use these adapted performance indicators to guide assessment of student competency for students completing placements in a telehealth setting.
Antimicrobial, antioxidant and quantitative phytochemical evaluation of the dichloromethane and methanolic leaf extracts of Solenostemon monostychus P. Beauv
Authors: Ere Diepreye  , Eboh Abraham Sisein  , Ovuru German Salvation
Published: June 2021

Solenostemon monostachyus P. Beauv (Lamiaceae family) is an important herb that is widespread in West and Central Africa.The leaves are used in various decoctions traditionally to treat diseases most especially microbial infections associated with the foot. In this study, the phytochemicals (qualitative and quantitative) of the plant were determined. The antimicrobial and antioxidant activities of the plant were also evaluated by standard methods. Results showed alkaloids, tannins, flavonoids, saponins phenolics in the methanolic extract of Solenostemon monostachyus. Cardiac glycosides and steroids absent in the methanolic extract were found present in the dichloromethane extract. The quantitative phytochemicals recorded were alkaloids (18.05 ± 0.87%), saponins (11.3 ± 0.56 %), tannins (3.3 ± 0.19 GAE). The antioxidant activity testing showed that the methanolic extract has higher DPPH scavenging ability over dichloromethane extract and standard ascorbic acid. In the antimicrobial activity testing, the cup-plate diffusion method was used and the result showed that the dichloromethane extract inhibited the growth of Bacillus species at concentrations 100 mg/ml, 50 mg/ml, 20 mg/ml and 10 mg/ml while methanolic extract inhibited the growth of bacillus species only at 100 mg/ml with 5 mm zone of inhibition. However, both methanol and dichloromethane extract showed no antimicrobial activity on the other test organisms such as Psudomonas aeruginosa, Escherichia coli and Staphylococcus aureus. In conclusion both methanolic and dichloromethane extracts of Solenostemon monostachyus are potential sources of antimicrobial and antioxidant.
Conceptual Background of Bioaccumulation in Environmental Science
Authors: Abdullateef Abdullahi Ibrahim  , Ali Gambo Yusuf  , Gambo Ismail  , Muhammad Abdullahi Ibrahim  , Abdulhamid Ruwa Musa  , Mustapha Said Sulaiman
Published: June 2021

Environmental metal pollution is one of the serious global problems with severe health effects due to its persistence and accumulation in living organisms, these require biological strategies such as bioaccumulation for remediation, the main environmental contaminants are associated to water, soil, and air. Meanwhile, Bioaccumulation is the accumulation of pollutants in living organisms which enable to assess the risk related to their presence in the ecosystems. In other words; Bioaccumulation is the net result of all uptake and loss processes, such as respiratory and dietary uptake, and loss by egestion, metabolism, passive diffusion, transfer to offspring and growth. Hence, this paper provides the conceptual background of bioaccumulation factors, effect of heavy metals on the ecosystems, and the organisms involved in the processes as well as some fishes and plants responsible for bioaccumulation.
Właściwości spoiw geopolimerowych
na bazie lotnych popiołów wapniowych
Authors: Błaszczyński Tomasz Z. , Król Maciej R.
Published: June 2021

Przeprowadzone badania oparto na mało popularnym w inżynierii lądowej popiele lotnym otrzymywanym ze spalania węgla brunatnego, który ma większą zawartość CaO (>4%). Materiał badano w celu zweryfikowania możliwości jego uzdatnienia, aby można go było zastosować do produkcji betonów geopolimerowych. Czynniki determinujące tok badań były związane z procesem wiązania, na który ma wpływ temperatura, ilość reagenta i czas obróbki cieplnej. Po usystematyzowaniu wyników badań wpływu podstawowych parametrów decydujących o wytrzymałości analizowanych betonów zbadano także wpływ rozdrobnienia popiołów lotnych wysokowapiennych
w celu zwiększenia wytrzymałości betonów
i zapraw opartych na tym spoiwie.
Personality trait stability and change
Authors: Bleidorn Wiebke , Hopwood Christopher J. , Back Mitja D. , Denissen Jaap J. A. , Hennecke Marie , Hill Patrick L. , Jokela Markus , Kandler Christian , Lucas Richard E. , Luhmann Maike , Orth Ulrich , Roberts Brent W. , Wagner Jenny , Wrzus Cornelia , Zimmermann Johannes
Published: June 2021

Personality traits continue to change throughout the lifespan. However, we still know little about when, why, and how personality traits change. In this paper, we review the current state of scientific evidence regarding the nature, sources, and processes of personality trait stability and change. We revisit past disputes over the relative importance of genetic and environmental influences, discuss studies on life events and personality trait development, and summarize theory and research on personality change processes. In doing so, we derive general principles of personality trait development, highlight limitations of past research, and present the broad outlines for future research on personality trait development, with a particular emphasis on relevant methodological issues and conceptual challenges.
1. indlæg: Gennemgang af QuickSubmit
Authors: Frederiksen Niels Erik
Published: June 2021

Her kan du se det første indlæg, der blev vist på vores webinar 10. juni 2021
Comparison of Road Traffic Death and Injury Rates at Pedestrian Crossings in Europe
Authors: Uhlmann Julius
Published: June 2021

For this study, accident statistics of 14 European countries were analysed for the number of fatalities and injuries occurring at pedestrian crossings from 2015 to 2017. The road traffic death rate (killed per 1 million inhabitants) and the road traffic injury rate (injured per 1 million inhabitants) at pedestrian crossings were calculated and compared. It was found that there are large differences between the European countries: The road traffic death rate at pedestrian crossings is the lowest in Great Britain and Germany and the highest in Poland and Lithuania. Statistical analysis showed a significant correlation between road traffic death and injury rates at pedestrian crossings.
Evaluation of the Organic Soil Compressibility from In-Situ and Laboratory Tests for Road Application
Authors: Chmielewska Iwona
Published: June 2021

Organic soil is characterised by high compressibility and should be improved so that it can be used for construction. The use of every method of soil improvement requires knowledge of the compressibility parameters. One of these parameters is the constrained modulus. The constrained modulus can be determined using laboratory or in-situ tests. In this study, the constrained modulus of organic soil was determined using oedometer and piezocone tests (CPTU). The author analysed subsoil under an approximately 250 m section of a designed road in north-eastern Poland. The constrained modulus of organic soil sampled from four different depths was determined in oedometer tests. Piezocone tests were conducted at 18 points located every 15 m along the length of the section concerned. To determine the constrained modulus based on the cone resistance from CPTU tests, the knowledge of the α and αM coefficients is needed. For the tested soil, the optimal range of the α coefficient from 0.4 to 0.7 was determined. The αM coefficient ranged from 0.4 to 0.8. The value of the constrained modulus of organic soil obtained from the oedometer tests, depending on the effective stress, ranged from approximately 100 kPa to 400 kPa. The constrained modulus of the tested soil decreased with depth, which both research methods proved.
IoT-IIRS: Internet of Things based intelligent-irrigation recommendation system using machine learning approach for efficient water usage
Authors: Bhoi Ashutosh , Nayak Rajendra Prasad , Bhoi Sourav Kumar , Sethi Srinivas , Panda Sanjaya Kumar , Sahoo Kshira Sagar , Nayyar Anand
Published: June 2021

In the traditional irrigation process, a huge amount of water consumption is required which leads to water wastage. To reduce the wasting of water for this tedious task, an intelligent irrigation system is urgently needed. The era of machine learning (ML) and the Internet of Things (IoT) brings it is a great advantage of building an intelligent system that performs this task automatically with minimal human effort. In this study, an IoT enabled ML-trained recommendation system is proposed for efficient water usage with the nominal intervention of farmers. IoT devices are deployed in the crop field to precisely collect the ground and environmental details. The gathered data are forwarded and stored in a cloud-based server, which applies ML approaches to analyze data and suggest irrigation to the farmer. To make the system robust and adaptive, an inbuilt feedback mechanism is added to this recommendation system. The experimentation, reveals that the proposed system performs quite well on our own collected dataset and National Institute of Technology (NIT) Raipur crop dataset.
Clostridium butyricum relieve the visceral hypersensitivity in mice induced by Citrobacter rodentium infection with chronic stress
Authors: Wang Tengfei , Li Lixiang , Li Shiyang , Zhao Hongyu , Qu Junyan , Xia Yanan , Li Yanqing
Published: June 2021

Background

Visceral hypersensitivity is a common symptom in patients with post-infectious irritable bowel syndrome (PI-IBS), and change of the microbiota is a vital etiological factor of it. Clostridium butyricum (C. butyricum) is one of the probiotics which is reported as the active components in the treatment of IBS, especially IBS with diarrhea. Citrobacter rodentium (C. rodentium) is an enteropathogenic bacteria which can produce self-limiting colitis in mice, which have been used to produce a PI-IBS-like mice model. Whether C. butyricum could influence the visceral hypersensitivity and gut microbiota of PI-IBS is still unknown. Our study aimed to examine whether the intervention of C. butyricum or antibiotics could affect the etiology of visceral hypersensitivity.

Methods

C57BL/6 male mice were gavaged with the C. rodentium to induce a infective colitis. The C. butyricum and antibiotic compound were used to intervene the infected mice 3 days later. A 9-day chronic water avoidance stress (WAS) process was implemented to help induce the visceral hypersensitivity. The abdominal withdrawal reflex (AWR) score was assayed to indicate the visceral hypersensitivity of different groups. On the 7th, 14th, and 30th days after infection, mice feces were collected and high-throughput sequencing was carried out to analyze their gut microbiota.

Results

Combined, the C. rodentium infection plus chronic stress (WAS) could induce the visceral hypersensitivity in mice. Treatment of the C. butyricum after C. rodentium infection could relieve visceral hypersensitivity of mice, while no difference was observed in the antibiotic treatment group. The gut microbiota diversity of C. rodentium infected mice was similar to the uninfected mice, while there were different microbial communities structure between them. The Shannon and Chao indexes significantly decreased in the antibiotic treatment group compared to other groups at 7th, 14th, and 30th days post-infection, while treatment of C. butyricum could maintain the indexes within normal range. At day 14 after infection, the structure of microbiota headed towards normality after the C. butyricum treatment. After the WAS, the Shannon and Chao indexes of the control group decreased and the structure of microbiota changed. The C. butyricum treatment could prevent these changes of the gut microbiota induced by WAS.

Conclusion

C. butyricum could relieve the visceral hypersensitivity in mice induced by C. rodentium infection plus chronic stress. It could also remodel the microbiota change caused by the infection and chronic stress. It may be a more effective treatment strategy for PI-IBS than antibiotics.
Swarm Intelligence-Based Feature Selection for Multi-Label Classification: A Review
Authors: Abdulazeez Adnan Mohsin , Hasan Dathar A. , Ahmed Awder Mohammed , Kareem Omar S.
Published: June 2021

Multi-label classification is the process of specifying more than one class label for each instance. The high-dimensional data in various multi-label classification tasks have a direct impact on reducing the eﬃciency of traditional multi-label classifiers. To tackle this problem, feature selection is used as an effective approach to retain relevant features and eliminating redundant ones to reduce dimensionality. Multi-label classification has a wide range of real-world applications such as image classification, emotion analysis, text mining and bioinformatics. Moreover, in recent years researchers have focused on applying swarm intelligence methods in selecting prominent features of multi-label data. After reviewing various researches, it seems there are no researches that provide a review of swarm intelligence-based methods for multi-label feature selection. Thus, in this study, a comprehensive review of different swarm intelligence and evolutionary computing methods of feature selection presented for the tasks of multi-label classification. To this end, in this review, we have investigated most of the well-known and state-of-the-art methods and categorize them based on different perspectives. We then provided the main characteristics of the existing multi-label feature selection techniques and compared them analytically. We also introduce benchmarks, evaluation measures and standard datasets to facilitate research in this field. Moreover, we performed some experiments to compare existing works and at the end of this survey, some challenges, issues and open problems of this field are introduced to be considered by researchers in future.
Computational Screening of Natural Compounds for the Discovery of Potential Aromatase Inhibitors: A Promising Therapy for Estrogen-Dependent Breast Cancer
Authors: Rafeeq Misbahuddin M. , Sain Ziaullah M. , Alturki Norah A. , Alzamami Ahmad , Asiri Saeed A. , Mashraqi Mutaib M. , Alqosaibi Amany I. , Alnamshan Mashael M. , Almutairi Abdulrahman , Alanazi Abdulkhaliq Munawir , Alam Qamre
Published: June 2021

Aromatase plays a significant role in the progression of estrogen receptor-positive (ER-positive) breast cancer. The adverse side effects of currently used aromatase inhibitors (AIs) necessitate the development of new AIs that are more active, selective, and less toxic. This study used a computational approach to screen 503 natural compounds ZINC database against the aromatase active site. The best scoring hits ZINC69482055, ZINC69482510, and ZINC406719 exhibited strong binding with aromatase, with binding energy values of -8.45, -10.35, and -8.75 kcal/mol, respectively, which is comparatively higher than that of the control compound Anastrozole (-6.43 kcal/mol). Docking analysis showed that the selected hits interacted with the crucial residues of the aromatase active site. This study suggested that these compounds could be used as possible AIs in the cure of breast cancer. Hands-on bench work validation is needed to optimize these compounds as AIs.
Another Tale from the Harsh World: How Plants Adapt to Extreme Environments
Authors: Dussarrat Thomas , Decros Guillaume , Díaz Francisca P. , Gibon Yves , Latorre Claudio , Rolin Dominique , Gutiérrez Rodrigo A. , Pétriacq Pierre
Published: June 2021

The environmental fluctuations of a constantly evolving world can mould a changing context, often unfavourable to sessile organisms that must adjust their resource allocation between both resistance or tolerance mechanisms and growth. Plants bear the fascinating ability to survive and thrive under extreme conditions, a capacity that has always attracted the curiosity of humans, who have discovered and improved species capable of meeting our physiological needs. In this context, plant research has produced a great wealth of knowledge on the responses of plants to a range of abiotic stresses, mostly considering model species and/or controlled conditions. However, there is still minimal comprehension of plant adaptations and acclimations to extreme environments, which cries out for future investigations. In this article, we examined the main advances in understanding the adapted traits fixed through evolution that allowed for plant resistance against abiotic stress in extreme natural ecosystems. Spatio‐temporal adaptations from extremophile plant species are described from morpho‐anatomical features to physiological function and metabolic pathways adjustments. Considering that metabolism is at the heart of plant adaptations, a focus is given to the study of primary and secondary metabolic adjustments as well as redox metabolism under extreme conditions. This article further casts a critical glance at the main successes in studying extreme environments and examines some of the challenges and opportunities this research offers, especially considering the possible interaction with ecology and metaphenomics.
Triisopropylsilyl‐Substituted Benzo[1,2‐b:4,5‐c′]dithiophene‐4,8‐dione‐Containing Copolymers with More Than 17% Efficiency in Organic Solar Cells
Authors: Jeong Mingyu , Oh Jiyeon , Cho Yongjoon , Lee Byongkyu , Jeong Seonghun , Lee Sang Myeon , Kang So‐Huei , Yang Changduk
Published: June 2021

Considering the special functions of fused‐ring aromatic building blocks and Si‐atom in high‐performance donor–acceptor‐conjugated materials at the same time, herein the synthesis of a novel fused‐ring tricyclic heterocycle, triisopropylsilyl‐substituted benzo[1,2‐b:4,5‐c′]dithiophene‐4,8‐dione (iBDD‐Si), an isomer of well‐known benzo[1,2‐c:4,5‐c′]dithiophene‐4,8‐dione is presented. The iBDD‐Si‐based copolymer series (PM6, PM6‐5Si, PM6‐10Si, and PM6‐15Si) is synthesized via Stille polymerization, revealing fine‐tuned optical and electrochemical properties, and molecular packing with varying iBDD‐Si contents in the backbone. Organic solar cells are fabricated by pairing the copolymer donors with nonfullerene acceptor N3 and characterized. High power conversion efficiency of more than 17% is achieved using the PM6‐5Si‐based solar cell, which is attributed to the balanced charge transport, enhanced charge generation/dissociation kinetics, and minimized total energy and recombination losses. It is demonstrated that iBDD‐Si is a promising backbone toolbox for various high‐performance conjugated materials.
Unadulterated Organic Nanoparticles with Small Sizes for Robust Tumor Imaging and Photothermal Treatment
Authors: Sun Tingting , Liu Hongmei , Jiang Nan , Wu Qihang , Li Chaonan , Xia Rui , Gao Baoxiang , Xie Zhigang
Published: June 2021

Phototheranostics integrating optical imaging and phototherapy have attracted massive attention in the context of precise tumor therapy. However, most of the reported phototheranostic systems have large sizes and complex structures due to either the extraneous carriers or cargos. Herein, the organic nanoparticles (terrylenediimide (TDI) NPs) are obtained from a TDI‐based single component in the absence of additives. The as‐prepared TDI NPs possess favorable small sizes of less than 20 nm, good photothermal stability, and high photothermal conversion efficiency. Especially, TDI NPs have the capacity for rapid and lasting tumor imaging, and effective photothermal therapy of cervical cancer upon irradiation. This work provides an alternative method to prepare multifunctional nanomaterials with simple structures, and sheds light on the potential applications of dye molecules as intrinsic theranostic agents.