bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring the Profound Impact of AI on Higher Education and Students
Authors: Emanuel Amy , Stone David H.
Published: February 2024

Recent advances in artificial intelligence (AI) and generative artificial intelligence (GenAI) are beginning and will continue to have a profound impact on industry and higher education (HE). This chapter presents an overview of the relationship between AI, industry, and HE with a focus on higher education institutions (HEI) and students who are beginning to navigate the implications of AI. Following a review of global HE institution's approaches and responses to GenAI, the current impact of AI on student's education journeys and their preparedness for an AI ready world is explored through a review of the opportunities and challenges AI presents, resulting in a thematic framework for HE institution considerations for traversing this new terrain.
Network Algorithms for Intelligent Evaluation of Composition in Middle School English Cloud Classrooms
Authors: Huang Yaohua , Zhang Chengbo
Published: February 2024

This study combines link grammar (LG) detector with N-grammar model to analyze and evaluate grammar in compositions. And then the composition level is judged through information entropy. Finally, the composition score is calculated based on the overall composition level and grammar weight. The experimental results show that the combined weight of recall and accuracy of the proposed method in this study is 89.9%, which is 26.6% higher than LG and 9.7% higher than Grammarly. In the performance test of scoring the entire essay, the proportion of error between the proposed method and manual evaluation is 87.29%, with a lower overall mean square error of only 3.08 and a shorter average running time of only 22.69 seconds. The method proposed in this study has a high accuracy and strong applicability in the evaluation of English compositions for middle school students, providing a new approach for teaching English writing for middle school students.
Envisioning the future empowering the physician
Authors: Manilgama S. R.
Published: February 2024

No abstract available
Priapism and pyrexia of unknown origin presenting as a relapse of multiple myeloma
Authors: Jayasinghe JSDND , Neththikumara U , Senevirathne SB , Sugathapala AGH , Ranasinghe N , Samaraweera Y
Published: February 2024

Pyrexia of unknown origin (PUO) is defined as a body temperature >38.3°C on several occasions for >3 weeks with failure of diagnosis despite one week of inpatient investigations or three outpatient visits. Aetiology for PUO may be infective, inflammatory, autoimmune, malignant, miscellaneous or remains undiagnosed. We describe a patient diagnosed with multiple myeloma (ISS-stage II) who completed induction chemotherapy and presented with PUO and extensive thrombosis as a complication of relapsed myeloma (very rare; 0.2% in myeloma). A 62-year-old man, with diagnosed multiple myeloma, achieved a very good partial remission after 6 cycles of bortezomib-thalidomide-dexamethasone regimen, presented with PUO and right lower limb deep vein thrombosis. His thrombosis was managed successfully with anticoagulation. While on therapeutic anticoagulation with warfarin and being investigated extensively for PUO without a focus, he developed priapism due to bilateral internal pudendal vein thrombosis. His anticoagulation was intensified to a target INR of 2.5-3.5. He recovered without residual damage. Despite broad spectrum antimicrobial agents, trial of antimalarial and anti-tuberculosis treatment, he remained pyrexial with rising inflammatory markers (ESR, CRP). Relapsed multiple myeloma was confirmed with 30% bone marrow plasma cells and raised serum monoclonal para-protein levels of 23.78g/L. He was restarted on chemotherapy with bortezomib-lenalidomide-dexamethasone. His PUO of two months subsided with one week of chemotherapy.

This case illustrates an atypical presentation of relapsed myeloma and highlights the importance of achieving early diagnosis with a systematic approach and making optimum treatment choice after careful evaluation of previous treatment, drug toxicities, patient’s condition and available treatment options.
Global Expanded Access Program for Pemigatinib in Patients with Previously Treated Locally Advanced or Metastatic Cholangiocarcinoma and Fibroblast Growth Factor Receptor Gene Alterations
Authors: Lindley Anouk , Prager Gerald , Bitzer Michael , Burn Timothy C. , Lihou Christine F. , Croft Elisabeth
Published: February 2024

Purpose Pemigatinib is a fibroblast growth factor receptor-2 (FGFR2) inhibitor approved for use in patients with previously treated cholangiocarcinoma (CCA) and FGFR2 fusions or rearrangements. This ongoing global Expanded Access Program (EAP) allows physicians in regions where pemigatinib is not commercially available to request pemigatinib for patients with locally advanced or metastatic CCA who, in the physician’s opinion, could benefit from pemigatinib treatment.Materials and Methods Eighty-nine patients from Europe, North America, and Israel were treated from January 2020 through September 2021.Results Patients had FGFR gene fusions (68.5%), rearrangements (12.4%), translocations (5.6%), amplifications (2.2%), and other alterations (11.2%). Median duration of treatment in the EAP was 4.0 months (range, 0.1 to 13.6 months). The most frequently reported adverse event (AE) was hyperphosphatemia (22.5%); the most common serious AE was cholangitis (3.4%). Treatment discontinuation was associated with reports of AEs for seven patients (7.9%). AEs associated with pemigatinib were consistent with those observed in clinical trials.Conclusion Efficacy was not assessed in this EAP. However, some patients remained on treatment for up to a year, suggesting that they observed a benefit from treatment. Patients with CCA should undergo molecular testing to identify those who could benefit from targeted treatments such as pemigatinib.
Erratum for “Slope Filtrations Revisited”
Authors: Kedlaya Kiran S.
Published: February 2024

Some corrections are given for the manuscript “Slope Filtrations Revisited”, Documenta Math., Vol. 10 (2005), 447-525.
Discapacidad, discursos de odio y redes sociales: video-respuestas a los haters en TikTok
Authors: García-Prieto Victoria , Bonilla-del-Río Mónica , Figuereo-Benítez Juan C.
Published: February 2024

Introducción: En los últimos años, la propagación de discursos de odio a través de redes sociales ha aumentado hasta convertirse en un problema cada día más preocupante en nuestras sociedades. Este estudio se enfoca en los discursos de odio hacia el colectivo de personas con discapacidad. El objetivo es analizar sus video-respuestas a los haters en TikTok, considerando aspectos como el contenido, el alcance, la interacción, el engagement, el tono y la intencionalidad de la propia respuesta. Así como profundizar en la perspectiva de los autores de las video-respuestas respecto al discurso de odio y su postura frente a este fenómeno. Metodología: La investigación incluye una metodología mixta, compuesta por análisis de contenido de 64 video-respuestas de TikTok publicadas por usuarios con discapacidad en respuesta a mensajes de odio recibidos en esta red social, y por 14 entrevistas estructuradas a usuarios entre los perfiles que integran la muestra. Resultados: Los resultados reflejan cómo, a los comentarios negativos, insultos, menosprecios o burlas que reciben otros colectivos, a este se suman otros contenidos como el capacitismo o la negación de la discapacidad. Conclusiones y discusión: Los hallazgos coinciden en que la expansión de discursos de odio es mayor en TikTok y apuntan a causas como la edad de los usuarios de esta red social, el funcionamiento del algoritmo o el anonimato que permiten las redes. Se exploran vías de reducción de los discursos de odio en redes sociales, enfocadas en el marco legal, la educación y la promoción de la salud mental.
Daily Step Count and its Association with Arterial Stiffness Parameters in Older Adults
Authors: Phababpha Suphawadee , Sri-amad Ruchada , Huipao Nawiya , Sriwannawit Porraporn , Roengrit Thapanee
Published: February 2024

Background: Daily step count is a simple parameter for assessing physical activity. However, the potential advantages of setting daily step goals below the traditional 10,000-step threshold remain unclear. The cross-sectional study aimed to determine the relationship between daily step counts and arterial stiffness outcomes in older individuals.Methods: Forty-eight older adults recorded their daily step counts over a 7-day period using a pedometer. The participants were classified into two groups based on their daily step count: Group 1 (n = 28) consisted of individuals taking fewer than 5000 steps per day, while Group 2 (n = 20) included those who recorded 5,000 to 9,999 steps per day. To evaluate arterial stiffness parameters, we measured pulse wave velocity (PWV), cardio-ankle vascular index (CAVI), and ankle-brachial index (ABI). Hemodynamic and biochemical parameters were also determined.Results: Participants who accumulated fewer daily steps exhibited higher PWV compared to each group. An inverse association was observed between average steps per day and PWV. However, no significant differences were found between daily step counts and CAVI or ABI.Conclusions: As individuals increase their daily step count, they may experience a reduction in arterial stiffness. Consequently, the assessment of daily steps has benefits for enhancing vascular health and overall well-being among older individuals.
Mapping Potential Malaria Vector Larval Habitats for Larval Source Management in Western Kenya: Introduction to Multimodel Ensembling Approaches
Authors: Zhou Guofa , Lee Ming-Chieh , Wang Xiaoming , Zhong Daibin , Githeko Andrew K. , Yan Guiyun
Published: February 2024

Identification and mapping of larval sources are a prerequisite for effective planning and implementing mosquito larval source management (LSM). Ensemble modeling is increasingly used for prediction modeling, but it lacks standard procedures. We proposed a detailed framework to predict potential malaria vector larval habitats by using multimodel ensemble modeling, which includes selection of models, ensembling method, and predictors, evaluation of variable importance, prediction of potential larval habitats, and assessment of prediction uncertainty. The models were built and validated based on multisite, multiyear field observations and climatic/environmental variables. Model performance was tested using independent field observations. Overall, we found that the ensembled model predicted larval habitats with about 20% more accuracy than the average of the individual models ensembled. Key larval habitat predictors in western Kenya were elevation, geomorphon class, and precipitation for the 2 months prior. Additional predictors may be required to increase the predictive accuracy of the larva-positive habitats. This is the first study to provide a detailed framework for the process of multimodel ensemble modeling for malaria vector habitats. Mapping of potential habitats will be helpful in LSM planning.
Benefits of Lot Testing to Improve the Quality of Malaria Rapid Diagnostic Tests in India
Authors: Srivastava Bina , Sharma Supriya , Swarnkar Deendayal , Ahmed Naseem , Valecha Neena , Anvikar Anupkumar R.
Published: February 2024

Since 2010, malaria rapid diagnostic tests (RDTs) are widely used to detect malaria. The Indian Council of Medical Research–National Institute of Malaria Research performed lot testing (LT) according to WHO procedures since 2016. Lot testing is performed to evaluate the lot-to-lot variation in performance of malaria RDTs. Four sets of positive quality control (QC) panels for P. falciparum (Pf) and P. vivax (Pv) and 10 negative panels tested RDTs. RDTs were reported as pass, failed, or deferred on the basis of WHO criteria. In the past 5 years, 275 lots containing 15,488 RDT kits for malaria diagnosis were subjected to LT. The monovalent RDTs (n = 1,216), based on either Pf histidine rich protein 2 (HRP2) or Pan-Plasmodium lactate dehydrogenase (Pan-pLDH) antigens, showed 90.4% sensitivity and 100% specificity, whereas RDTs based on HRP2 + Pan-pLDH or HRP2 + pLDH (n = 13,924) had sensitivity 95.6% and specificity 99.5%, respectively. RDTs based on PfHRP2 + Pv-pLDH + Pan-pLDH (n = 348) had 100% sensitivity and specificity. In a comparison between HRP2 + pLDH or HRP2 + Pan-pLDH to HRP2 + pLDH + Pan-pLDH RDTs, it was found that the sensitivity of PfHRP2 with Pan-pLDH RDTs (n = 2,382) was only 83%. Of the 275 lots analyzed, 15 lots of PfHRP2 with Pan-pLDH were deferred. The QC panel for Pf revealed a faint Pan band in the tested lots, which is a cause for concern. The results of deferred lots were reported to concerned government agencies. Quality-compromised RDTs may lead to an incorrect diagnosis. It is critical to have a QC system in place for effective malaria management.
Digital Gangrene Associated with Scrub Typhus: A Case Series
Authors: Singh Jitendra , Dinkar Anju , Kumar Nilesh , Kumar Kailash , Tejan Nidhi
Published: February 2024

Rickettsial diseases cover a broad spectrum of illnesses. Scrub typhus is present worldwide, and Orientia tsutsugamushi is the causative agent of this chigger mite–borne infectious illness. Infections exhibit a range of severity, from mild illness to the more severe manifestation of multiorgan failure. We report three cases of scrub fever (55-year-old female, 63-year-old female, and 29-year-old male), all cases developed focal or pan-digital gangrene. All cases were successfully treated by administering doxycycline and additional supportive measures. Digital gangrene is uncommon in scrub typhus. Clinical suspension for early diagnosis and appropriate treatment may avoid further complications.
The Climate Impact of Medical Residency Interview Travel in the United States and Canada: A Scoping Review
Authors: Kaelin Sarah , Durfey Shayla , Dorfman David , Moretti Katelyn
Published: February 2024

Background The change from in-person to virtual interviews for graduate medical education (GME) provides the opportunity to compare the potential environmental effects.

Objective To explore and summarize the existing literature on the potential climate impact of medical residency interview travel through a scoping review.

Methods The search was conducted in October 2022 using 5 research databases. Results were screened for inclusion by 2 reviewers in a 2-tiered process. Inclusion criteria were limited to English language articles from the United States and Canada, with no limitations on the type of study, type of applicant (allopathic, osteopathic, or international medical graduate), or type of residency. A thematic analysis focusing on the objectives and main findings of identified studies was conducted and an iteratively created standardized data extraction worksheet was used such that all studies were explicitly assessed for the presence of the same themes.

Results The search identified 1480 unique articles, of which 16 passed title and abstract screening and 13 were ultimately included following full-text review. There were 3 main themes identified: the carbon footprint of residency travel, stakeholders’ perspectives on virtual interviews, and advocacy for virtual interviews. All 13 articles employed persuasive language on interview reform, ranging from neutral to strongly in favor of virtual interviews based wholly or in part on environmental concerns.

Conclusions Two main findings were identified: (1) Though carbon footprint estimates for in-person interviews vary, in-person interviews create considerable carbon emissions and (2) those working in GME are concerned about the climate effects of GME practices and describe them as a compelling reason to permanently adopt virtual interviewing.
Reference values for haematology and biochemistry parameters in the Pelagonian Pramenka sheep breed
Authors: Dodovski Petar , Hristovska Talija , Pejcinovska Natasa , Dameski Pance , Karabolovski Nikola , Ristevski Mimi
Published: February 2024

The Ovcepolian type of Pramenka sheep is most prevalent in Pelagonia region. It is considered a valuable source of genetic diversity, characterised with a number of beneficial traits. Haematology and biochemistry measurements is important for health assessment of animals. The aim of this study was to determine the reference ranges for selected haematology and biochemistry parameters in the Pelagonian Pramenka sheep breed. The study was carried out on 55 clinically healthy, non-pregnant sheep, 1 to 3 years old, during spring season, from three different locations in the Pelagonia region, North Macedonia. Blood samples were collected from the jugular vein into vacuum tubes with an anticoagulant for haematological analysis and vacuum tubes free of anticoagulant for biochemical analysis. Reference values may be more adequate as it is later, for biochemistry parameters. Reference values for hematology parameters were: leukocytes, lymphocytes, midsize cells, cells correlating to monocytes, eosinophils, basophils, blasts and other precursor white cells, granulocytes, haemoglobin, haematocrit, erythrocytes, erythrocyte indices (average volume per litre, average haemoglobin in erythrocytes, average haemoglobin concentration per litre, and platelets). Reference values for biochemistry parameters were: total proteins, albumins, total bilirubin, total cholesterol, creatinine, glucose, HDL-cholesterol LDL-cholesterol, triglycerides, urea, aspartate aminotransferase, alanine amino transferase, alkaline phosphatase, glutamyl transferase, lactate dehydrogenase, and the concentrations of calcium, magnesium and inorganic phosphate. Most obtained values were comparable to other strains of Pramenka sheep. There was a clear deviation of certain reference values compared to the literature. Further analysis should be conducted to determine the reference values in rams and lambs.
The influence of sunflower oil in meals on the blood mineral profile of dairy cows
Authors: Šaljić Ermin , Hrković-Porobija Amina , Šerić-Haračić Sabina , Tandir Faruk , Varatanović Maja , Ćutuk Amel , Čengić Benjamin
Published: February 2024

Minerals are essential substances with an important function in livestock, and their disbalance negatively affects the health and production, especially of ruminants. The addition of fat to the rations of dairy cows impacts the overall and mineral metabolism, and thus on health and production. The aim of the research was to examine the correlative relationships between balanced production meals and the mineral status of lactating cows with different ration compositions with or without the presence of vegetable oil. The research was conducted on 30 dairy cows of the Holstein breed at the Butmir farm, Sarajevo, Bosnia and Herzegovina. Three groups of 10 animals were formed based on productivity (A, 13-15 kg of milk/day, B, 19-21 kg of milk/day and C, 25-27 kg of milk/day). Samples of feed, blood plasma and milk of animals were collected on three occasions a 3-week intervals. According to the feed analysis results, the rations were standardized for each group, given for three weeks without oil,and then for three weeks with the addition of sunflower oil in the amount of 2.5% of the ration dry matter. After determining the content of basic nutrients, dry matter and ash in the rations, the concentrations of Ca, Mg, Na and K were determined by atomic absorption spectrophotometry,while the colorimetric method was used to analyse P according to Woy and Eggertz-Finkener. Analysis of blood mineral parameters was performed spectrophotometrically. The content of fat, proteins, lactose, and non-fat dry matter in milk samples was determined by infrared spectrometry using an automatic analyser. Based on the results, we observed a similarity in changes of values and the statistical significance of the differences in plasma Ca, P and Mg between the study groups and at sampling intervals. Milk production was positively correlated with the concentration of Mg and Ca with addition of the sunflower oil to the meal, while no correlation coefficient was established for P in any of the samplings. Balanced meals with and without the addition of oil did not significantly affect the content of Ca, P or Mg in the blood plasma of the tested animals, nor were significant differences found between the groups. However, by determining the correlations between milk parameters and blood biochemical parameters, a significant positive correlation was established between the amount of milk and Ca and Mg levels with a diet supplemented by oil. Given that the addition of sunflower oil in the amount of 2.5% of dry matter of the balanced rations for cows had no negative effects on the mineral profile and the parameters of the tested animals, we conclude that the introduction of this oil could be useful both from the economic point and improving nutritional composition of milk as an animal food present in the daily human diet.
МЕНТОРСКА ПРАКСА У ШКОЛАМА
Authors: Марковић Славица
Published: February 2024

This paper presents the results of the research on mentoring practice in schools of the Nišava district with the aim of showing the current situation in terms of trainees’ preparation for work, their assessment of various aspects of the role of mentors and the need for permanent professional development of both mentors and trainees. As in modern education, in terms of introducing beginners to the work process, more and more demands are placed on experienced professionals, so their tasks are also complicated in terms of supporting trainees during the first year of work and ensuring that the work is performed at a high level of quality and expertise. The research conducted for the purposes of this paper included 24 interns from the Nišava district who completed their internship in the last five years. By analyzing the results obtained, it can be concluded that the intern’s self-evaluation based on the concept of readiness for a professional role shows a high degree of success, which indicates good mentoring support and successful communication between mentors and trainees, but also the need for professional development in educational policies and efforts for quality education in the RS.
Determination of mutagenic potentials of diarylmethylamine based imine compounds by ames test and computational molecular docking
Authors: Akar Sultan , Çırak Tuğba , Hüsunet Mehmet Tahir , Turkdonmez Ipek , Kenger İbrahim Halil , Aslan Ferhat , Kardöl Ahmet , Yıldız Hamit , Zencir Sevgi , Emek Ayşe Gizem , Kayraldız Ahmet
Published: February 2024

In recent years, studies that investigate the effects of chemical compounds on organisms have increased in direct proportion to their widespread use. In this study, four different bidentate imine ligands and bidentate imine ligands+Cu(II) complexes were synthesized from the bioactive synthetic diarylmethylamine compound. After the ligands and metal complexes obtained were purified using chromatographic and analytical methods, their mutagenic effects were investigated with the Ames/Salmonella test system. In addition, interactions of four different Cu(II) complexes with B-DNA were evaluated with molecular docking analysis. Accordingly, the results indicated a significant increase in the colonies formed in the presence (+S9) and absence (-S9) of the metabolic activation system, meaning a mutagenic effect against strain TA98 and TA100 strains in general.
Prominence Analysis of President Jokowi's Speeches on the Palestine–Israel Conflict: Acoustic Phonetic Study
Authors: Ayuanda Winda , Syarfina Tengku , Gustianingsih Gustianingsih , Muskar Rahlina , Erwina Emmy
Published: February 2024

The aim of this research is to represent the prominence contained in President Jokowi's statements regarding the Palestinian and Israeli conflicts, as well as to find the values of frequency, duration, and intensity as characteristics of the sound. This research is quantitave research with an instrumental approach. The research data is an audiovisual form, and it is analyzed using the Praat application. The result shows that the prominence of President Jokowi's statement is found in the words 'indonesia' and 'war', namely in the rightmost syllables: -sia and -rang. When communicating, speakers tend to pay more attention to words that they think are important.  It has also been proven that the factors that influence the formation of prominence are pitch, loudness, and duration, with values of F0, intensity, and duration for stressed syllables is higher than unstressed syllables. Apart from that, prominence can also occur when speakers want to highlight words that are considered important.
СУДНОВІ АВТОМАТИЗОВАНІ ЕЛЕКТРОЕНЕРГЕТИЧНІ СИСТЕМИ: Навчальний посібник
Authors: ЯРОВЕНКО В.О. , ЗАРИЦЬКА О.І.
Published: February 2024

Навчальний посібник містить стислий огляд суднових електроенергетичних систем та комплексів. Розглянути основи технічної експлуатації суднових електростанцій, системи автоматичного регулювання напруги та частоти струму суднових синхронних генераторів, системи автоматичної синхронізації та розподілу навантаження між паралельно працюючими генераторними агрегатами, системи захисту та сигналізації. В посібнику надано пристрої та системи управління тепловими двигунами Зульцер Rt-flex, система управління ВРШ типа KAMEWA, системи управління приводами керма виробництва ROLLS – ROYCE. Відповідає вимогам дипломування електромеханіків – Розділу A-III/6 Кодексу з підготовки і дипломування моряків та несення вахти (Кодекс ПДНВ), а також враховує рекомендації Типового курсу Міжнародної морської організації 7.08 «Електромеханік» (Electro-Technical Engineer, Model course 7.08, 2014 Edition). Призначено для студентів електромеханічних спеціальностей при вивченні електрообладнання суден. Може бути корисним викладачам у навчальному процесі.
Організація технічної експлуатації електричного обладнання і автоматики суден. Навчальний посібник
Authors: ЦАЦКО В.І. , ЯРОВЕНКО В.О. , КРИВОРУЧКО Д.Ю.
Published: February 2024

Навчальний посібник містить стислий виклад загальних питань організації технічної експлуатації електрообладнання, вплив на нього дестабілізуючих та компенсуючих факторів, основ його раціонального вибору та використання. Розглянуті елементи теорії надійності та технічної діагностики електрообладнання, прилади, інструменти та матеріали, що використовуються при технічній експлуатації. Він знайомить з науковими базисними положеннями технічної експлуатації суднового електрообладнання та електричних засобів автоматики, що дозволяють на практиці ефективно реалізувати заходи щодо технічного використання, обслуговування та ремонту. Вивченню даної дисципліни повинні передувати вивчення вищої математики (найбільш важливі розділи алгебри логіки, теорії ймовірностей і математичної статистики) і проходження плавальної практики, що дає загальне представлення про організацію служби на судах і деякі практичні навички обслуговування електроустаткування. Відповідає вимогам для дипломування електромеханіків Розділу A-III/6 Кодексу з підготовки і дипломування моряків та несення вахти (Кодекс ПДНВ), а також враховує рекомендації Типового курсу Міжнародної морської організації 7.08 «Електромеханік» (Electro-Technical Engineer, Model course 7.08, 2014 Edition). Призначено для студентів електромеханічних спеціальностей при вивченні технічної експлуатації електричного та електронного обладнання суден. Може бути корисним викладачам у навчальному процесі.
Evaluasi dan Pengelolaan Lereng Bekas Tambang Breksi Andesit Dusun Siluk Kelurahan Selopamioro Kepanewon Imogiri Kabupaten Bantul Daerah Istimewa Yogyakarta
Authors: Alwiyah Alwiyah , Lukito Herwin , Kristanto Wisnu Aji Dwi , Nugroho Nandra Eko , Suharwanto Ir.
Published: February 2024

Siluk Area, Selopamioro Village, Imogiri District, Bantul Regency, Special Region of Yogyakarta, is one of the active community mining sites. These mining activities leave slopes that are not treated or repaired, so that they become a threat to soil and/or rock mass movements for the surrounding community. One of the former mining areas in Siluk hamlet is very close to residential areas. Therefore, it is necessary to study the stability and safety factors of the slope so that they can be the basis for determining the direction of ex-mining slope management.The methods used were literature studies, field surveys and mapping, and laboratory tests. The sampling method used was the purposive sampling method. Samples taken were used for testing physical properties (content weight, moisture content, porosity, and grain size), shear angle, and cohesion. The analysis methods used are the simplified Janbu method and the descriptive analysis method to evaluate the slope of the former mine. Based on calculations and testing, it is found that the three slopes are categorized as steep slopes with a safety factor value on the central and south-north slopes of 0.156, 0.620, and 0.367. Slope management carried out involves a change in slope geometry with the cut and fill method, planting vegetation in the form of Sengon trees, and planting land cover in the form of Vertiver grass
Perencanaan Sistem Penyediaan Air Minum (SPAM) Dan Pengolahan Air Kelurahan Pattan Ulusalu Kecamatan Saluputti
Authors: Pranata Dian , Masiku Reynaldi Palindo , Dasmasela Blessing C. J , M.LPaembonan
Published: February 2024

Sistem penyediaan air minum Kelurahan Pattan Ulusalu saat ini belum memadai untuk memenuhi kebutuhan air masyarakat. Sumber air berada di Salu Tandung adalah salah satu mata air yang mampu menjadi air baku untuk melayani masyarakat Kelurahan Pattan ulusalu.

Penelitian diawali dengan mengambil sampel air dan kemudian menguji kualitas air. Kemudian dilakukan pengambilan data debit air dan data penduduk  lalu diproyeksikan untuk 10 tahun kedepan. Setelah debit dan kebutuhan air pada 10 tahun kedepan didapatkan, maka dibuat perencanaan bangunan air.

Dari hasil penelitian diperoleh kandungn air mengandung bakteri e.coliform sebanyak 4700/100ml yang disebabkan oleh pembusukan dedaunan dan pohon yang berada disekitar sehingga dilakukan upaya pembuatan instalasi pengolahan air dilengkapi dengan kaporit Ca(OCl2) antara 60-70% yang mampu membunuh bakteri e.coliform. Dengan debit 8,3L/detik atau 717.120L/Hari setelah diproyeksi mampu untuk memenuhi kebutuhan air sebanyak 121.246L/Hari hingga tahun 2030. Maka direncanakan reservoir umum yang mampu menampung air sebanyak 40m3 untuk didistribusikan ke masing-masing lingkungan dengan cara gravitasi dengan dimensi pipa transmisi pipa HDPE Ø3” dan pipa distribusi  HDPE Ø1,5”.
Identifikasi Sumber Air di Lembang Parinding dan Cara Pemanfaatan Berdasarkan Pengetahuan Lokal
Authors: Fitriyani  , Randanan Frans Andri , Ambali Dian Pranata Putra , Puspita Sari Rini , Mijas Ruba Rantelangnga  , Yody Batto’ Parrang
Published: February 2024

Air merupakan sumber daya alam yang mempunyai peran dan fungsi penting bagi kehidupan masyarakat. Air dibutuhkan manusia dan seluruh makhluk hidup lainnya, maka dari itu setiap daerah memiliki pengetahuan lokal mengenai masalah  pemanfaatan sumber daya air untuk memenuhi kehidupan sehari-hari. Penelitian ini menjelaskan bagaimana masyarakat yang berada di daerah dataran rendah berbukit dengan posisi sungai berada di bawah lahan pertanian dapat bertahan hidup dengan adanya pengetahuan lokal yang dilakukan.Penelitian ini di lakukan di Lembang Parinding Bori’ Dusun Utara Kabupaten Toraja Utara. Analisis penelitian ini berfokuskan pada macam-macam sumber daya air dan pengunaan air oleh penduduk setempat.  Metode penelitian yang di gunakan yaitu  teknik pengumpulan data secara observasi lapangan dan data sekunder. Berdasarkan informasi dari masyarakat,sumber air yang terdapat di Lembang Parinding Bori’ Dusun Utara diantaranya Busso Bulayan dan Pokko’ dan terdapat dua sungai yaitu salu Tonggo dan Busso Bulayan, sumber air tersebut digunakan untuk kebutuhan mandi, memasak, mencuci dan juga pertaian, namun  sumber air tersebut akan keruh ketika hujan berkepanjangan, akan tetapi hanya berlangsung selama 1-2 hari saja setelah itu air akan jernih kembali. Cara pemanfaatannya dilakukan dengan cara menggunakan pompa air,atau dapat menggunakan timba, ember ataupun bambu.  Salah satu pengelolaan yang dilakukan adalah dengan menutupi tanah sekitar sumur dengan semen
Efektivitas Lubang Resapan Biopori terhadap Laju Resapan (Infiltrasi) di Kampus 2 UKI TORAJA
Authors: Paembonan Gisto , Julio Joshua T  , Joey Andreanto Kombong Padang  , Ardi Prokhorus  , Frengkiy  , Ambali Dian Pranata Putra
Published: February 2024

Di sekitaran area kampus 2 UKI TORAJA kecematan Tallunglipu sering di temukan genangan air akibat terjadinya curah hujan yang cukup tinggi dan juga laju resapan tanah terhadap air yang kurang.Penelitian ini bertujuan untuk mengetahui laju resapan tanah terhadap air dengan menggunakan efektifitas lubang resapan biopori dan tanpa biopori,dengan menggunakan alat berupa pipa  dengan diameter 18 cm yang di masukkan ke dalam lubang sedalam 80 cm.Resapan adalah proses masuknya air ke dalam permukaan tanah,dengan mengetahui laju resapan tanah terhadap air kita dapat menanggulangi permasalahan yang sering terjadi yaitu lambat nya laju resapan.Peneltian di lakukan dengan pengambilan data selama 30 menit,laju resapan tercepat untuk lubang tanpa biopori terjadi di minggu ke-2 tepatnya terjadi di 5 menit pertama yaitu sedalam 15,8cm dan untuk lubang dengan biopori terjadi di minggu pertama tepatnya di menit ke-5 sedalam 7cm,dan untuk lubang tanpa biopori resepan paling lambat terjadi di menit ke-20 tepatnya di minngu ke-2 sedangkan untuk lubang dengan biopori laju resapan paling lambat terjadi di menit ke-30 minggu pertama dengan penurunan hanya sebesar 0,3cm.Berdasarkan hasil penelitian di atas di temukan bahwa lubang resapan tanpa biopori laju resapan nya lebih cepat di bandingkan dengan lubang resapan dengan biopori.Faktor yang mempengaruhi ketidakakuratan data  adalah alat dan bahan yang masih sangat minim ditambah lagi faktor tanah yang kurang presisi dan beberapa faktor eksternal lainnya.
ANALISIS MUTU BETON READY MIX PADA PROYEK PEMBANGUNAN RUSUNAWA MAHASISWA UKI TORAJA
Authors: Elson Tanga  , Reni O. Tarru  , Harni Eirene Tarru
Published: February 2024

Penggunaan ready mix sangat dibutuhkan dalam pelaksanaan pembangunan dengan alasan penggunaanya yang cepat dan mudah. Kualitas beton yang baik sangat tergantung dari homogenitas beton itu sendiri. Faktor yang mempengaruhi adukan mutu beton yaitu alat atau metode yang digunakan, lama pengadukan serta campuran material bahan beton itu sendiri, sehingga tujuan dari penelitian ini adalah untuk mengetahui kuat tekan beton dan tingkat homogenitas dari mutu beton ready mix. Metode dalam penelitian ini dilakukan untuk mendapatkan nilai kuat tekan beton, standar deviasi dan koefisien variasi dari mutu beton yang digunakan pada Pembangunan Rusunawa Mahasiswa UKI Toraja. Pengujian kuat tekan pada saat umur beton mencapai 3 hari, 7 hari, 14 hari dan 28 hari, dan pengujian slump dilakukan pada saat pengecoran beton. Hasil penelitian menunjukkan kuat tekan beton rata - rata pada umur 3 hari sebesar 46,21 kg/cm², umur 7 hari sebesar 71,68 kg/cm², umur 14 hari sebesar 125,06 kg/cm² dan umur 28 hari sebesar 183,92 kg/cm². Menurut SNI 03-6815-2002 dari tabel standar kontrol standar deviasi dan koefisien variasi pada umur 28 hari dengan nilai standar deviasi sebesar 64,83 kg/cm² dan nilai koefisien variasi sebesar 35,25 % menunjukkan homogenitas dari benda uji yang di buat dari beton ready mix yang digunakan pada Proyek Pembangunan Rusunawa Mahasiswa UKI Toraja dikategorikan kurang homogen.
Measurement Tool for The Influence of Sales Promotion, Utilitarian Motive, Self Esteem Motive, and Hedonic Motive on Purchase Decision with Impulse Buying and Behavior Intention as Variable Intervening in E-commerce XYZ
Authors:   School of Economics and Business, Telkom University, Indonesia, Laraswati Virnanda , M.M., Ph.D Prof. Dra. Indrawati, ,   School of Economics and Business, Telkom University, Indonesia
Published: February 2024

One proof of the ease of technology is the emergence of e-commerce. E-commerce is a medium that allows sellers and buyers to meet face-to-face. This research aims to provide a measurement tool to analyze the influence of sales promotion, utilitarian motive, self-esteem, and hedonic motive on purchasing decisions with impulse buying and behavioral intention as intervening variables. This research surveyed with the participation of 30 respondents who had purchased products through XYZ e-commerce Therefore, this measuring instrument meets the requirements and is acceptable for further research.
Authentic Deeds as Evidence in Civil Cases
Authors:   Faculty of Law, Wijaya Kusuma Surabaya University, Subagiyo Dwi Tatak , Herlina Indah ,   Magister of Law, Faculty of Law, Wijaya Kusuma Surabaya University, Jelita Aura ,   Magister of Law, Faculty of Law, Wijaya Kusuma Surabaya University, Alifiandi Martio Pratama ,   Faculty of Law, Wijaya Kusuma Surabaya University, Setiawan Ahmad ,   Magister of Law, Faculty of Law, Wijaya Kusuma Surabaya University
Published: February 2024

Deeds in law have a very important function and role in proving to resolve legal problems, especially authentic deeds. Authentic deeds in resolving civil cases are very important for determining rights and obligations when a dispute arises from a civil legal relationship. In social life there is always a gap between practice and theory, especially regarding the rights and obligations of the parties. The existing problems are: 1. how to apply Authentic Deed Evidence in civil cases in court, 2. what is the judge's consideration (legal reasoning) in assessing authentic deeds which are argued to have dwaling (mistake), fraud (bedrog) or coercion (dwang) . Based on the analysis of normative juridical research, it will be clear that: First, the application of authentic deed evidence in civil cases in court is based on statutory regulations as stated in statutory regulations, namely Article 1866 of the Civil Code and Article 164 HIR, which consists of: a .documentary evidence, b. witness evidence, c. allegation, d. confession, and oath. Second, that the judge's consideration (legal reasoning) in assessing an authentic deed which is postulated to be dwaling (mistake), fraud (bedrog) or coercion (dwang) is and is based on the existence of general facts and specific facts in making a decision and is based on the judge's confidence in determining The quality of the decision is based on Article 1865 of the Civil Code, Article 163 HIR. According to this system, evidence must focus on the main arguments relating to rights or facts, as long as they are denied by the opposing party.
Drug prescribing and health-related quality of life among pregnant women attending antenatal clinics at two health facilities in Bayelsa State, Nigeria
Authors:   Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria, Ganiyu Kehinde A , Johnson Chukwuma M ,   Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria, Erah Patrick O ,   Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
Published: February 2024

Purpose: To study drug prescribing and health-related quality of life (HRQoL) among pregnant women who attended antenatal clinics at Amassoma General Hospital and Amassoma Comprehensive Health Center in Bayelsa State from January to April, 2018. Methods: Pertinent patients’ (n=152) data evaluated included diseases presented, systolic and diastolic blood pressure (SBP/DBP), including medications prescribed. Also, patients’ HRQoL data incorporating both physical and mental components were assessed using Short Form-12v2 questionnaire. All data generated were analyzed as appropriate and mean values for HRQoL data described in relation to the mid-point norm, 50±10. Results: Pains, malaria, and cough/catarrh were treated in 45 (41.7%), 15 (13.9%), and 13 (12.0%) of the pregnant women, respectively among other conditions. Proportions of the subjects with normal SBP and DBP were 145 (95.4%) and 137 (90.1%). In all, 149 (98.0%) of the women were prescribed routine medications required in pregnancy comprising folic acid, ferrous, and vitamin C, although 29 (24.0%) of those (n = 121) who were eligible for intermittent preventive treatment (IPT) for malaria in pregnancy did not receive the therapy. Analgesics, tetanus toxoid, and artemisinin-based combination therapy were widely prescribed for management of pains, prevention of tetanus, and treatment of malarial infection, respectively. On the average, the state of pregnancy impacted both physical (47.56±6.92) and mental (46.88±8.50) health states among the women comparably (p>0.05), and substantial proportion (38.2%) of the cohort were at risk of screening positive for first stage depression. Conclusion: Pains, malaria, and cough/catarrh were the most encountered conditions, while analgesics, tetanus toxoid, and artemisinin-based combinations were the majorly prescribed medications among the pregnant women. Also, virtually all of the women received routine medications required in pregnancy. On the average, their physical and mental health statuses were impacted similarly. Keywords: Amassoma, Drug Utilization, Health-Related Quality of Life, Pregnancy
Development of colorimetric method for the assay of artesunate using 4-nitrobenzaldehyde
Authors:   Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Benin, PMB 1154, Benin City, 300001, Nigeria, Aghayere Godfrey E
Published: February 2024

Purpose: Artesunate is one of the artemisinin derivatives that is commonly used in combination with some anti-malarials as artemisinin-based combination therapies. High performance liquid chromatographic technique is the required standard assay method for artesunate, but this is not readily available or affordable in most developing countries. This study was carried out to develop a simple, accurate and cost-effective assay method for quantitative determination of artesunate. Methods: The method is an indirect colorimetric assay, which was developed from the formation of yellow coloured product due to the reaction between acid decomposed product of artesunate with 4-nitrobenzaldehyde. Results: The wavelength of maximum absorption for the yellow coloured product was 474 nm. The Beer’s law was obeyed at the range of 20-100 µg/ml artesunate concentration with a linear coefficient of 0.9996. The molar absorptivity was 2.3183×103 mol-1 cm-1. The limit of detection and quantification were 0.0753 µg/ml and 0.2283 µg/ml, respectively. The method required water as diluent. The result obtained from recovery study confirmed that there was no interference from pharmaceutical excipients. Five brands of artesunate tablets were assayed using the developed method. Conclusion: The results compared favourably well with those obtained using the official method described in the international pharmacopoeia. The developed method is useful for the quantitative determination of artesunate in tablets and raw pharmaceutical material. Keywords: Artemisinin, quantitative determination, in-direct colorimetric assay, molar absorptivity
Bacteriology of Some Liquid Herbal Products Sold in Ilorin- Kwara State Nigeria
Authors:   Department of Pharmaceutical Microbiology and Biotechnology, University of Ilorin, Belllo Ronke H , David Mosebolatan S ,   Department of Pharmaceutical Microbiology and Biotechnology, University of Ilorin, Olutayo Abiodun O ,   Department of Pharmacognosy and Drug Development, University of Ilorin, Abdulrazaaq Khadijat O ,   Department of Pharmaceutical and Medicinal Chemistry, University of Ilorin, Olufadi–Ahmed Haishat Y ,   Department of Pharmaceutical Microbiology and Biotechnology, University of Ilorin, Salami Omatseye T ,   Department of Pharmaceutical Microbiology and Biotechnology, University of Ilorin, Lawal Bilqis A ,   Department of Pharmacognosy and Drug Development, University of Ilorin, Akerele John O ,   Department of Pharmaceutical Microbiology, University of Benin, Benin City, Nigeria
Published: February 2024

Purpose: This study aims to establish the safety and/or potential public health dangers associated with the consumption of liquid herbal preparations (LHP) sold in Ilorin-Kwara State. Methods: Ten LHPs were randomly collected from three locations, kept under cold chain and transported to the Laboratory. All samples were evaluated for bacterial load using aerobic plate count method and bacterial isolates were presumptively identified using standard microbiological methods. Furthermore, Gram negative bacteria were identified using 12A Microbact ® Identification kits. Results: Sixty percent (60%) were fresh and faint, 4 (40%) were stale and putrid in smell as well as free of foreign matter. pH and bacterial load of samples ranged from 3.60 to 9.75 and 2.5 x 102 to 4.4 x 106 CFU/ mL respectively. Five (5) genera of bacteria, namely; Klebsiella species 10 (29.41%), Bacillus subtilis 8 (23.53%), Enterobcter spps. 7 (20.59%), Staphylococcus aureus 6 (17.65%) and Serretia marcescens 3(8.82%) were isolated from these LHPs. All isolates were resistant (100%) to Sulphamethoxazole trimethoprim combination. Amoxocillin clavulanate was active against 62.50% of K. pneumonia and S. marcescens isolates. Also 50% of K. oxytoca and E. gergoviae were susceptible to Amoxocillin clavulanate combination. Approximately, 8 (80%) of LHPs had bacterial load of 2.5 x 102 to 4.4 x 106 CFU/ mL and 2 (20%) yielded no growth. In addition, 40% of LHPs had bacterial load of 106 CFU/mL beyond the 104 CFU/mL permissible limit stated by European Pharmacopoeia. Conclusion: The observed high bacterial load and the presence of S. aureus as well as enteric bacteria of public health importance in these LHPs underscore the potential risk inherent in the consumption of these preparations. Therefore, public health awareness campaign on the dangers of unapproved LHPs consumption should be instituted. Keywords: Liquid herbal preparations, bacterial contaminants, Ilorin metropolis
Assessment of pH, titratable acidity, and caffeine content of some brands of energy drinks
Authors:   Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Benin, PMB 1154, Benin City, 300001, Nigeria, Ogbeide Uyi M , Irene Daniel E ,   Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Benin, PMB 1154, Benin City, 300001, Nigeria, Okeri Henry A ,   Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Benin, PMB 1154, Benin City, 300001, Nigeria
Published: February 2024

Purpose: Caffeinated beverages that contain high levels of stimulant ingredients, usually caffeine, as well as sugar and often supplements, such as B vitamins or carnitine, and that are promoted as a product capable of enhancing mental alertness and physical performance are referred to as energy drinks. Energy drinks are generally consumed by adolescents and athletes. This study aims to evaluate the endogenous pH, titratable acidity, and caffeine content in selected brands of energy drinks commonly consumed by athletes and adolescents in Benin City. Methods: Eight (8) commonly consumed energy drinks were evaluated. A digital pH meter was used to measure the pH of the selected energy drinks and the titratable acidity was evaluated by titrating 0.1N sodium hydroxide solution against 30 ml of each energy drink till the end-point was reached. The caffeine content was determined by titrating the caffeine-iodine complex formed against standard sodium thiosulphate using iodometric back titration. Results: All the energy drinks were acidic with a pH ranging from 2.61 to 3.48 which is less than the critical pH (5.5). The titratable acidity of the energy drink samples ranged from 5.1 to 15.6 g/100 ml and the caffeine content varied from 0.029 to 0.165 mg/ml. Conclusion: The outcome of this study confirms that energy drinks had low pH values and high titratable acidity except for ED G and ED H with low titratable acidity and low caffeine content. Keywords: Caffeine, endogenous, energy drinks, pH, titratable acidity