bluuebunny/crossref_metadata_2025 huggingface dataset:
Estratégias utilizadas para diminuir a taxa de falha na extubação de prematuros: Revisão de Literatura
Authors: Duque Junqueira Thaisa , Martins Pinto Patrícia
Published: December 2022

A extubação de bebês prematuros ainda é apresentada como um grande desafio para os médicos. A falta de critérios e métodos seguros para a realização de uma extubação bem sucedida gera uma maior taxa de falha e acarreta em um pior prognóstico destes recém nascidos. Neste estudo foi realizada uma busca nas bases de dados National Center for Biotechnology information (PubMed), The Directory of Opem Access Journals (DOAJ), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), por meio das palavras chaves: “premature”, “extubation” e “failure”, sendo encontrados 323 artigos e após os critérios de inclusão e exclusão, foram utilizados 21,  que abordavam estratégias para um desmame seguro, como modelos de ventilação não invasiva, critérios clínicos a serem avaliados, e o uso de outras ferramentas para auxiliar nesse processo com o objetivo de avaliar quais estratégias realmente têm impacto para uma melhora na extubação .Observando-se que há modos de ventilação promissores como o NIPPV e o CPAP que ainda é o mais utilizado, e quando combinado com medidas clínicas constitui uma das estratégias mais eficientes.

Palavras – Chave: Prematuro; Extubação; Falha.
Determinants of Hospital Choice among Patients and Perceptions of the Same among Hospital Employees in a Tertiary Care Corporate Hospital in Mumbai, India
Authors: Singh Swati , Lakshmi Vani , Somu G , Kamath Rajesh
Published: December 2022

Introduction:

In recent times, the choice has become an important factor in healthcare as patients can compare hospitals and healthcare providers using the abundance of information at their disposal. Patients now want to be more involved in their treatment decision-making process and at times seek information about their conditions as well as different types of available treatment options. This makes them aware consumers. They hold the key to the domain of healthcare marketing and the best way to understand patients’ expectations is to understand the factors that affect their decision-making process.

Methods:

The prospective observational study was conducted on 252 patients and 56 employees of a tertiary care corporate hospital in Mumbai, using a structured questionnaire.

Results:

This study highlights the major factors that affect patients’ decisions when it comes to selecting a hospital. These factors are competent medical and support staff, emergency and laboratory services, the reputation of the hospital among the public, cost of services, hospital location and infrastructure. Looking at the same situation from an administrative employee’s perspective gives us an insight into how they think patients decide on a hospital.

Discussion:

The significance of this study is derived from this need of exploring the concept of patient choice from not only the consumer’s (patients’) perspective but service providers (employees) too. Patient choice factors and the service response to those factors form an important part of the patient experience with a provider, thus impacting their satisfaction.

Conclusion:

The study thus sheds light on the way patients select a hospital and the measures the hospital administration needs to take to increase their acceptance by the patients, leading to greater patient satisfaction and hence patient loyalty.
estereotipos y los roles de género en las películas Disney
Authors: Rubio Méndez Sheila , Sevilla-Vallejo Santiago
Published: December 2022

Las películas Disney ofrecen modelos de género a los niños sobre los cuales es necesario aplicar el pensamiento crítico. Este estudio reflexiona sobre los estereotipos y roles de género y cómo estos afectan y se transmiten en la sociedad. En este sentido, las películas infantiles adaptan estereotipos y roles de los cuentos tradicionales en los que están basadas. Este trabajo valora en qué medida las películas perpetúan o transforman la representación femenina a lo largo de las generaciones. Se ha analizado una película de cada una de las etapas de Disney (etapa clásica, renacimiento de Disney y segundo renacimiento) para observar la evolución que estas tienen a lo largo de los años.
Pezizales (Ascomycota) asociados a bosque de pino-encino en Yécora, Sonora, México
Authors: Madriz-Valdovinos David , Raymundo Tania , Gutiérrez Aldo , Sánchez Flores Marcos , L. Coronado Martha , Esqueda Martín
Published: December 2022

Antecedentes y Objetivos: Pezizales es uno de los órdenes del reino Fungi más estudiados en el mundo y el segundo grupo de ascomicetos mejor conocido en México con 185 especies. En contraste, existen solo 23 especies registradas para Sonora. El objetivo de este estudio fue determinar la riqueza taxonómica de Pezizales asociados al bosque de pino-encino en una localidad del municipio de Yécora, Sonora, México.Métodos: Se realizaron cinco muestreos estacionales en bosque de pino-encino de Los Pilares, Yécora, Sonora durante los años 2020-2021. La determinación taxonómica se hizo con claves especializadas con base en la caracterización macro- y micromorfológica de los especímenes.Resultados clave: Se determinaron 16 especies de Pezizales distribuidas en siete familias: Helvellaceae (5), Pezizaceae (2), Pseudombrophilaceae (1), Pulvinulaceae (1), Pyronemataceae (4), Sarcosomataceae (1) y Sarcoscyphaceae (2). Doce especies son nuevos registros para Sonora y seis para México: Geopyxis deceptiva, Helvella dryophila, Plectania milleri, Pseudombrophila fuscolilacina, Pseudopithyella magnispora y Tricophaeopsis latispora. Además, los tres últimos taxones se citan por primera vez para el continente americano.Conclusiones: El catálogo de Pezizales de Sonora se incrementó a 35 especies; no obstante, es importante dar continuidad a estudios que incluyan análisis ecológicos y filogenéticos de este grupo de hongos.
Proceedings of the 2020 Mathematics in Industry Study Group
Authors: Thamwattana Natalie , Meylan Michael , Roberts Anthony John
Published: December 2022

MISG 2020

University of Newcastle, Australia

28 January -- 1 February, 2020

This special Section of the ANZIAM Journal (Electronic Supplement) contains the refereed papers from the 2020 Mathematics and Statistics in Industry Study Group (MISG 2020) held at the University of Newcastle from 28 January -- 1 February 2020. The MISG is a special interest meeting of ANZIAM, the Australia and New Zealand Industrial and Applied Mathematics (ANZIAM) division of the Australian Mathematics Society. The MISG meetings take place annually and provide a forum where projects proposed by industry can be worked on intensively, by high profile scientists in the fields of Applied Mathematics, Statistics and Operations Research, from Australia, New Zealand and the world beyond, along with representatives from the industries proposing the projects.
The writing of these papers was coordinated by the project moderators in consultation with the coauthors and company representatives. The manuscripts were submitted to the editors, Associate Professor Mike Meylan, Professor Ngamta Thamwattana and Professor Tony Roberts, and were subsequently refereed by two expert referees. On the advice of the referees, manuscripts were accepted for publication, subject to the recommended revisions, and formally approved by the editorial committee.
At MISG 2020, six projects were presented from diverse industries, with 78 delegates participating.
Industry Partners
We gratefully acknowledge the support of our industry partners:

Lovells Springs;
Safearth;
Concrush;
Hyper Q Aerospace.

Acknowledgements
In addition to our industry partners, we gratefully acknowledge support from the following organisations:

ANZIAM;
Office of the NSW Chief Scientist \& Engineer, Department of Industry, NSW Government;
Priority Research Centre: Computer Assisted Research Mathematics and its Applications, The University of Newcastle;
Faculty of Science, The University of Newcastle.

We are also grateful to Professor Ryan Loxton from the Centre for Optimisation and Decision Science, Curtin University, for giving a public lecture on power of optimisation research in mining, energy, and agriculture industries, as part of the MISG's outreach event and acknowledge the support from the Hunter Branch of the Royal Society of NSW in promoting the public lecture. We are also grateful to Professor Mark McGuinness (Victoria University of Wellington), Professor Troy Farrell (Queensland University of Technology), Associate Professor Amie Albrecht (University of South Australia) and Dr Neville Fowkes (University of Western Australia) for their helpful advice and comments in organising the MISG 2020.
MISG2020 Organising Committee

Professor Ngamta Thamwattana (Co-Director)
Associate Professor Mike Meylan (Co-Director)
Mrs Juliane Turner (Administrative Support)
Dr David Allingham (Technical Support)
A scoping review and systematic map of primary studies assessing heat stress on reproductive, physiological, and productive parameters of farm animals
Authors: Diaz Daniel , Lopez-Orrantia Ana Maria , Camacho Asly Nicol , Rosiles Rene Jose , Rodriguez-Gaxiola Miguel Angel , Romo-Rubio Javier Alonso , Portillo-Loera Jesus Jose , Gaxiola Soila Maribel , Montero-Pardo Arnulfo
Published: December 2022

Heat stress induces failures in the physiological mechanisms that regulate the body temperature of farm animals and causes a loss in their productive and reproductive potential. Thus, we performed a scoping review to systematically map, describe, and classify primary research that assessed the effect of heat stress on the reproductive, physiological, and productive parameters of livestock. Electronic databases were searched to retrieve full-text, peer-reviewed experimental or cohort studies published from 1980 to August 2018. We included in vivo and in vitro studies exposing animals or cells to heat stress conditions and used a control group. Studies were evaluated based on title and abstract and then selected for final inclusion based on full text. We performed data charting to describe and visualize the evidence. In total, we included 466 studies, among which bovines and porcines were the most frequent species studied. Reproductive and physiological parameters were the main groups of outcomes assessed, and studies using adult females predominated. Seventy percent of the studies were experimental, and almost half of the studies used natural environmental conditions to assess the effect of heat stress in animals. Most of the studies were performed in the Americas and Asia, and three journals provided one-third of the publications. The systematic evidence synthesis presented herein outlines the trends of research performed to assess the effect of heat stress on livestock and allowed us to define future secondary studies to extend our knowledge about the negative impact of heat stress on the productivity of farm animals.
ASTRONOMY FOR STUDENTS WITH VISUAL IMPAIRMENTS: DEVELOPMENT OF THE CAREER EXPLORATION LAB
Authors: Madura T. I. , Christian C. , Wild T. , Hurd D. , Harris J. , Bartolone L. , Silberman K. , McVoy S. , Walker K.
Published: December 2022

For students with visual impairments (VI), the possibility of a future in astronomy, or any science, technology, engineering, and mathematics (STEM) field, seems daunting. In order to bolster astronomy and STEM opportunities for high school students with VI in the United States, we developed the STEM Career Exploration Lab (CEL). Our STEM CEL methodology employs tactile astronomy instruction via 3D printing technologies and unique 3D-printed models, professionals with VI acting as role models, and partnerships with local STEM industries that provide insights into possible career paths. In partnership with the South Carolina Commission for the Blind (SCCB) and the Michigan Bureau of Services for Blind Persons (MBSBP), to date we have held four weeklong CELs (June 2017, June & July 2018, August 2019) and a 3D printer build workshop (September 2018), thus far serving about fifty students with VI. We have also held one professional development workshop for teachers of the visually impaired at the Maryland School for the Blind in October 2021. We gathered pre- and post-intervention data via student surveys, assessments of students' astronomy knowledge, and video recordings of the CEL activities in order to study to what extent the CEL model can enhance the students' attitudes towards, interests in, and capacities to participate in astronomy and STEM careers. Once fully tested and refined, we will make our 3D model files and activities freely available for further use and study. This work serves as a testbed for an expanded CEL program aimed at helping increase the representation of persons with VI in astronomy and STEM fields. This work is supported by a generous Innovative Technology Experiences for Students and Teachers (ITEST) grant from the National Science Foundation.
DEDOSCOPIO: AN INCLUSIVE PROJECT DEDICATED TO BRING TACTILE ASTRONOMY TALKS
Authors: Fuentes-Muñoz C. , Paredes-Sabando P.
Published: December 2022

Dedoscopio have developed outreach activities focused on people with visual disabilities since 2018 in Chile. The initiative uses homemade low-cost tactile materials as a medium to represent astronomical concepts and physical phenomena. During the quarantine time, we started a Audio-Reading Club with blind and visually impaired children from two parts of Chile. It was such a success that it crossed the borders and we were able to reach Bolivian children.
ASTRONOMY EDUCATION RESEARCH: EFFORTS TOWARDS TEACHING FOR DIVERSITY AND INCLUSIVITY IN SOUTH AFRICA
Authors: Makwela T. , Taylor D. , Blyth S. , Allier S.
Published: December 2022

Many students are attracted to astronomy due to its inviting nature of spectacular wonders. However, studying astronomy goes beyond these wonders, which poses a challenge to students' knowledge and understanding of basic astronomical phenomena. The University of Cape Town has developed a series of research studies that probe the nature of student difficulties at a fine-grained level, in particular looking into how students conceive of astronomical distances which are beyond immediate human comprehension. The key experimental findings from this study were that as distances increased different modes of thinking were employed to make sense of them. The experimental findings could be explained by the embodied cognition framework which posits that the way we think (all thought) is ultimately grounded in infant sensory-motor experiences. In this case, the thinking template or image schema was suggested to be the "source-path-goal". Having identified the "thinking" framework allows for a research-based construction of learning activities that lead to sense-making. Thus, the notion of the Source-Path-Goal Thinking Template / Image Schema was used to create an activity that would trigger this mode of thinking for large-scale distances. Based on the current experimental findings that can be explained by an "embodied cognition" framework, learning activities were piloted that appear to have had a measure of success.
THE IAU-WOMEN IN ASTRONOMY WORKING GROUP AND INCLUSIVITY
Authors: Hasan P. , Pandey-Pommier M. , Vargas Domínguez S. , Piccialli A. , Saad Hassanin A. , Lazzaro D. , Norman D. J. , Wilkes B. J. , Leibacher J. , Lagos C.a D. P. , Masegosa J. , Yang L. , Valls-Gabaud D. , Bamba A. , Nastula J.
Published: December 2022

The International Astronomical Union Women in Astronomy (IAU WiA) working group (WG) is a part of the IAU Executive Committee that supports the needs and endeavours of women astronomers and initiates actions to advance equality of opportunity for women and men in astronomy. The new organizing committee of the IAU WiA WG was set-up in August 2021 with a 4-point plan, to enhance (i) awareness & sustainability via surveys, (ii) training and skill building, (iii) fundraising & (iv) communication via dissemination of results in conferences, WG Magazines, newsletters, etc. to facilitate the career of women in astronomy. In this publication we provide an overview of IAU WiA WG activities with a special focus on the Training and Skill Building efforts that can be adapted for differently-abled and marginalised women researchers.
Food Donation Application: Software Development Life Cycle Case Study
Authors: Jaybhaye Prof. Sangita , Jadhav Rohit , Kandhare Sushil , Karode Ganesh , Karpe Omkar
Published: December 2022

Abstract: Many people face starvation because of food shortages. Food shortages in developing countries are common. Smallholders and laborers are the most affected. In addition, in the current pandemic, laborers' employment has been taken away, leaving them unable to feed themselves and their families. There are several ways and means to help the needy, but nothing works better than making a contribution to an organization dedicated to helping poor communities battle against poverty. People living in NGOs also face food shortage issues. This application can help needy people eat food. With the help of this application, restaurants can serve food to many people.
Prácticas de cultivo de la flor de muerto (Tagetes erecta L.) y móviles culturales
Authors: Serrato Cruz Miguel Ángel
Published: December 2022

El cultivo y uso tradicional de las flores cempoalxóchitl (Tagetes erecta L.) en “Días de Muertos”, es tema poco estudiado. En el presente ensayo se analizó cualitativamente información sobre actividades festivas y uso del cempoalxóchitl, prácticas de cultivo y móviles culturales a partir de entrevistas en comunidades de México durante 19 años, observaciones directas, fuentes etnohistóricas y publicaciones científicas. La festividad tiene elementos comunes y otros diferentes, como su cultivo. La siembra se realiza en almácigo-trasplante, o directa­mente en suelo roturado, sin surco o en surco; las dos primeras de origen prehispánico. La siembra tradicional, desde mediados de junio hasta mediados de agosto, coincide con meses del calendario mexica en los que se utilizaron flores cempoalxóchitl. En las diferentes formas y tiempo de siembra, asociadas con diversidad am­biental y étnica, la emisión de botones florales inmaduros ocurre al final de septiembre, inicio de floración y floración completa a mediados y final de octubre, respectivamente, correspondiendo a meses prehispánicos donde no se festejaba a los muertos ni se usaba cempoalxóchitl. En el área funeraria prehispánica y panteón actual de Mitla, la presencia de la cruz se plantea como símbolo de vida y muerte asociados con el sol y las flores cempoalxóchitl.
Prevalence and effect of cannabis use in acute pancreatitis of unknown etiology
Authors: Tran Hanna
Published: December 2022

A clinical decision report using:

Simons-Linares CR, Barkin JA, Wang Y, et al. Is There an Effect of Cannabis Consumption on Acute Pancreatitis?. Dig Dis Sci. 2018;63(10):2786-2791. https://doi.org/10.1007/s10620-018-5169-2

for a patient with cannabis-associated acute pancreatitis.
Baclofen as a helpful alternative in treatment of painful paroxysmal attacks from trigeminal neuralgia
Authors: Ryan Samantha
Published: December 2022

A clinical decision report using:

Fromm GH, Terrance CF, Chattha AS. Baclofen in the treatment of trigeminal neuralgia: double-blind study and long-term follow-up. Ann Neurol. 1984;15(3):240. https://doi.org/10.1002/ana.410150306

for a patient with paroxysmal attacks from trigeminal neuralgia who is unable to take carbamazepine.
Territorios circulares
Authors: Zazo-Moratalla Ana
Published: December 2022

"2022 marks the 50th anniversary of the Meadows report, which warned in 1972, about growth limits and the finite nature of natural resources for the development system. It would take until 1987 for the UN to publish the Brundtland Report, initially known as Our Common Future, and define the concept of sustainable development, highlighting the moral need to responsibly use resources for the planet’s conservation. Nevertheless, this concept, tired and distorted today, did not explicitly imply critically viewing the prevailing linear model based on extraction, production, consumption, and waste. In this sense, the concept of “circularity” builds upon that of sustainable development since it reorients the current production model towards the closure of its cycles, thus assimilating them to natural ecosystems. Circularity aims at building a virtuous circle that minimizes the resources used at their origin, as well as the output waste, through repair, reuse, or recycling."
Age-related and Gender Aspects of Inflammatory Bowel Diseases in the Republic of Dagestan
Authors: Akhmedkhanov S. Sh. , Abakarova G. H. , Beibalayeva A. T. , Abdullayeva B. S. , Saidova Z. M.
Published: December 2022

Aim: Creation of a patient registry in the Republic of Dagestan to study various aspects of the course and outcomes of IBD, depending on the age and gender of patients.Materials and methods. We have created a register of IBD patients in the Republic of Dagestan. It included 168 IBD patients aged 17 to 70 years, 69 males and 99 females, the average age of patients with IBD was 38.1 ± 2.5 years with an average duration of illness of 6.19 ± 0.71 years. The diagnosis of IBD was established on the basis of the characteristic clinical picture of the disease, objective status, results of laboratory, endoscopic, X-ray and morphological research in accordance with Russian Clinical GuidelinesResults. The prevalence of IBD in the Republic of Dagestan is 5.41 cases per 100,000 population. The progression of IBD is more often observed in women, aged 30 to 39 years, residents of rural areas. Anemia (mainly chronic iron deficiency) was registered in 66.1 %, more often in women, its maximum frequency was noted in patients aged 20–29 years (80 %). Disability due to IBD was registered in 55.4 % of patients.Conclusions. The creation of a register of IBD patients in the Republic of Dagestan is aimed at monitoring the state of health, timely monitoring of the effectiveness of therapy and improving the quality of medical care.
Lenvatinib Therapy in Patients with Unresectable Hepatocellular Carcinoma in Real Clinical Practice
Authors: Petkau V. V. , Sultanbaev A. V. , Menshikov K. V. , Antipin A. S. , Volkonsky M. V. , Filippova V. M. , Vasilyeva Yu. V. , Tarkhanov A. A. , Mukhitova M. R. , Murzalina M. Zh. , Safarova A. R.
Published: December 2022

Aim. To determine lenvatinib treatment outcomes in patients with advanced unresectable hepatocellular carcinoma (uHCC) in real clinical practice.Patients and methods. A multicenter retrospective observational study included 58 patients with a confirmed uHCC diagnosis receiving lenvatinib. At baseline, ECOG, Child-Pugh and BCLC scores were assessed. The objective response rate (ORR), disease control rate (DCR), median overall survival (OS) and median progression-free survival (PFS) rates were assessed. In addition, adverse effects (AE) during treatment were monitored.Results. The median OS and PFS comprised 14.6 (95 % CI 10.6–18.6) and 11.1 months (95 % CI 8.31–13.8), respectively. The ORR amounted to 32.8 %, while DCR reached the level of 79.3 %. The levels of ORR and DCR were not statistically significantly different between the patients with stages B and C according to the BCLC staging system, with grades 0 and 1 according to ECOG, with classes A and B according to the Child-Pugh score, with viral and non-viral HCC etiology, with and without extrahepatic spread, and with and without portal vein invasion. Patients with alpha-fetoprotein (AFP) blood levels <200 ng/mL showed significantly higher ORR and DCR compared to those with AFP levels >200 ng/mL (44.4 % vs. 13.6 %, p = 0.015; and 88.9 % vs. 63.6 %, p = 0.021, respectively). The uHCC stage according to BCLC, ECOG functional status, Child-Pugh class, presence or absence of extrahepatic spread and viral etiology had no effect on the OS and PFS median levels. Patients with macroscopic portal vein invasion had a significantly lower PFS compared with those lacking this complication: 3.97 (0.00-8.07) vs. 11.1 (8.46-13.7), p = 0.053. AFP levels ≥200 ng/mL adversely affected survival rates: median OS comprised 12.0 (5.95-18.9) months in the group of patients with AFP ≥200 ng/mL vs. 16.1 (8.73-23.5) months in the group of patients having AFP <200 ng/mL, p = 0.020. AEs were registered in 81.0% (n = 47) of patients. Among the most common AEs were arterial hypertension (32.8 %), weakness (24.1 %), weight loss (12.1 %) and appetite loss (10.3 %). Due to AEs, Lenvatinib was withdrawn in 5 (8.6 %) patients.Conclusion. Lenvatinib confirmed its efficacy and safety in patients with uHCC in real clinical practice. The treatment outcome might be affected by AFP levels and the presence of macroscopic portal vein invasion. Further comparative studies into treatment regimens applied in real clinical practice are required.
IMPROVING MEDICAL IMAGE PIXEL QUALITY USING MICQ UNSUPERVISED MACHINE LEARNING TECHNIQUE
Authors: Ahmed Syed Thouheed , S Sreedhar Kumar , Guptha Nirmala S , N L Lavanya , Basha Syed Muzamil , Fathima Afifa Salsabil
Published: December 2022

Biomedical image processing and decision making is a growing research demand under global pandemic situation. The quality of medical images plays a vital role in streamlining remote diagnosis and processing via telemedicine platform, in providing unambiguous results and decision supports. This paper presents an improved Medical Image Content Quality (MICQ) technique and it aims to enrich the Magnetic Resonance (MR) image content or pixels based on semi supervised clustering technique for the process of deeper analysis and investigation to identify the normal and abnormal portions. The proposed (IMICQ) system is containing three stages namely pre-processing, clustering and validation respectively. In the pre-processing stage, the MICQ divides the MR image into finite number of non-overlapping blocks or vectors with size (2*2). Next stage, the proposed MICQ system iteratively partitions the MR image dataset or vector set into optimum number of highly relative dissimilar clusters based on K-Means clustering technique. In the last stage, the proposed system measures the quality of clustering result which obtained in the previous stage based on Effective Cluster Validation Measure (ECVM). Experimental results show that the MICQ is better suitable to improve MR image content quality for telemedicine platform and to predict the normal and abnormal portions over the image with higher accuracy ratio.
A Study on Farsi Handwriting Styles for Online Recognition
Authors: Ghods Vahid , Kabir Ehsanollah
Published: December 2022

Knowing varieties of writing a letter in a word or a subword in different handwriting styles is very beneficial in recognition specifically for online recognition. In this paper, TMU-OFS dataset consisting of 1000 frequent Farsi subwords is employed to study Farsi handwriting styles. The subwords are grouped based on their delayed strokes and their main bodies, separately. The handwriting styles in this dataset are analyzed and the wrongly spelled or incorrect structural samples are extracted. Finally, the second version of the dataset is introduced by considering the handwriting styles. The preliminarily results show a significant improvement in recognition of subwords based on their styles.
Alfabetização científica e popularização da ciência
Authors: Araújo Michell Pedruzzi Mendes , Corte Viviana Borges , Genovese Cinthia Leticia de Carvalho Roversi
Published: December 2022

A pandemia causada pela Covid-19 e o negacionismo científico presenciado nas ruas e nas redes sociais provocaram reflexões acerca da importância de uma educação científica crítica. Dessarte, por meio do presente ensaio, procurou-se tecer reflexões acerca das contribuições e dos desafios da Alfabetização Científica e da Popularização da Ciência no ensino de ciências da natureza para a formação de cidadãos críticos. O texto também problematiza a importância da educação em ciência e tecnologia em uma sociedade dominada por interesses econômicos. Por se tratar de um ensaio, a metodologia configura-se como pesquisa bibliográfica teórico-conceitual. A conclusão, a partir das discussões realizadas, apontam que a Alfabetização Científica e a popularização da ciência são promissoras, podendo contribuir para a formação crítica de estudantes que atuarão na sociedade com conhecimento científico, responsabilidade e autonomia de pensamento.
Educação Científica Intercultural para justiça social
Authors: Brasil Elizabeth Detone Faustini , Foerste Gerda Margit Schütz , Trazzi Patricia Silveira da Silva
Published: December 2022

Neste texto discutimos a importância de problematizar a formação inicial de professores de Química que envolva a Educação Científica Intercultural nas licenciaturas das Ciências da Natureza. Para isso, defendemos que a perspectiva da Educação Científica Intercultural pode contribuir para problematizar racionalidades presentes nos cursos de formação inicial de professores acerca da natureza do conhecimento científico, visando contribuir para a justiça social. Como aporte metodológico, inspiramo-nos na pesquisa participante, utilizando como instrumentos de produção de dados, registros em diários de campo, rodas de conversa com audiogravações. Os resultados evidenciam que processos coletivos de investigação em aproximação com diferentes saberes promovem diálogos interculturais, os quais possibilitam o enfrentamento de visões equivocadas a respeito do pensamento científico. Concluímos reforçando a necessidade de inserção dos pressupostos teóricos da Educação Científica Intercultural na formação inicial de professores, como forma de potencializar um currículo culturalmente e socialmente orientado na formação inicial de professores de Ciências da Natureza.
Model system to analyze RNA-mediated DNA repair in mammalian cells
Authors: Tschage Lisa , Kowarz Eric , Marschalek Rolf
Published: December 2022

“RNA-templated/directed DNA repair” is a new biological mechanism that
has been experimentally demonstrated in bacteria, yeast and mammalian
cells. Different RNAs or artificial DNA/RNA hybrid molecules have been
used to study their role in DNA double-strand break (DSB) repair. Recent
work also demonstrated that small non-coding RNAs (DDRNAs produced by
DICER, Drosha) and/or newly RNAPII transcribed RNA (dilncRNA) are
orchestrating the initial steps in DSB repair processes, giving another
hint for the involvement of RNA in DNA repair processes. Here we
demonstrate that pre-mRNA molecules could be used for DSB repair. Our
mamma¬lian cell culture system is based on 3 components: (1) a mutated
reporter gene producing an intron-containing pre-mRNA, (2) an
sgRNA-guided dCas13b::ADAR RNA editor specific for this pre-mRNA, and
(3) I-SceI to create a transient DSB situation. We were able demonstrate
that the ADAR-edited pre-mRNA is being used in cis for DSB repair,
thereby converting the mutated reporter gene into an active reporter
gene due to reconstituted splicing. We also used overexpression and
knock-down of several proteins to investigate their putative role in
this novel RNA-mediated DNA repair (RmDR) pathway. Based on our data,
RNA can be used as template for DNA repair processes.
Novel molecular resources for single-larva barcoding of enigmatic crustacean y-larvae
Authors: Dreyer Niklas , Palero Ferran , Grygier Mark , Savchenko Alexandra , Kolbasov Gregory , Machida Ryuji , Chan Benny , Olesen Jørgen
Published: December 2022

The enigmatic “y-larvae” (Pancrustacea: Facetotecta) still have an
incompletely understood lifecycle, and their adult forms remain unknown
despite their discovery more than 100 years ago and their documented
global occurrence from shallow waters to the deep-sea. Only two of the
17 formally described species, all based on larval stages, have been
investigated using an integrative taxonomic approach that, besides
providing descriptions of the morphology of the naupliar and cyprid
stages, also made use of exuvial voucher material and DNA barcodes. To
improve our knowledge about the systematics and phylogenetics of
y-larvae, we developed a novel protocol that maximizes the amount of
morphological, ecological, and molecular data that can be harvested from
single individuals of these tiny larvae. This revolves around single
larva barcoding, and includes daily imaging of y-nauplii reared in
culture dishes, mounting of their last naupliar exuviae on a slide as a
reference voucher, live imaging of the y-cyprid instar that follows, and
fixation, DNA extraction, amplification, and sequencing of the y-cyprid
specimen. By developing and testing a suite of new primers for both
nuclear and mitochondrial protein-coding and ribosomal genes, we
estimated the most comprehensive phylogeny of Facetotecta to date. We
expect that our novel procedure will help to unravel the complex
systematics of y-larvae and show how these fascinating larval forms have
evolved. Moreover, we posit that our protocols should work on larval
specimens of a diverse array of molting marine invertebrate taxa.
Identifying the Palliative Care Needs of Patients and Families in Gynecologic Surgical Oncology: A Scoping Review
Authors: Joost Klaudia Agnieszka , Washington Karla T. , Faurot Mary , Alexander Rachel L. , Craig Kevin , Tuller Erin R.
Published: December 2022

Patients undergoing oncology-related gynecologic surgical procedures
experience substantial symptom burden and distress. Support from
specialist palliative care teams may benefit these patients and their
families; however, an evidence-informed approach to the integration of
palliative care and gynecologic oncology is needed. To inform such an
approach, a scoping review synthesizing current evidence on the
palliative care needs of patients and families in gynecologic surgical
oncology was performed. Reviewers performed a structured search of
online databases CINAHL, Scopus, PsycINFO, MEDLINE, and PubMed in
addition to the grey literature to identify relevant studies published
between 2011 and June 11th, 2021. The original search identified 993
articles, which were dually screened for study inclusion, resulting in a
final sample of articles from which data were systematically extracted
and synthesized. This review of 59 publications predominantly consisted
of European studies (n=26, 44.1%), described quantitative study methods
(n=47, 79.6%), followed an observational study design (n=49, 83.1%),
and focused on psychological impact of treatment as a major topic of
study (n=21, 35.6%). The dataset also described sexual function of
women post treatment (n= 15, 25.4%), quality of life (n=10, 16.9%),
therapeutic decision making (n= 9, 15.2%), pain assessment (n=2,
n=3.6%), and medication for symptom management (n=2, 3.6%). Explicit
discussion of specialist palliative care involvement was rare. The needs
of patients and families in gynecologic surgical oncology are
well-suited to palliative care collaboration; however, the body of
literature on palliative care services provided to this unique
population is underdeveloped.
Clinical Manifestations and Risk Factors of Tigecycline-associated Thrombocytopenia
Authors: Zhu Yuanchao , ZHAO FEI , LIANG LIANG , JIN PENGFEI
Published: December 2022

Objective: To analyze the clinical features and risk factors of
tigecycline-associated thrombocytopenia. Methods: A retrospective
case-control study of patients who were treated with tigecycline was
conducted between January 2018 and June 2022. Results: A total of unique
506 patients were screened in this study. 12.3% of patients experienced
thrombocytopenia. thrombocytopenia developed 2 to 22 days after the
initiation of tigecycline, with a median (25-75th percentile) of 9
(6–11) days. Mild to moderate (grades 1-2) thrombocytopenia occurred in
60.9% (28/46) patients and severe (grades 3-4) thrombocytopenia
occurred in 39.1% (18/46) patients. In the multivariate analysis,
age≥74 years (p=0.028), risk of malnutrition (p<0.001),
tigecycline therapy for ≥7 days (p=0.003), DBIL>8.1μmol/L
(p<0.001)), BUN>8.1mmol/L (p=0.002) were
independent risk factors associated with thrombocytopenia. 70.7%
(65/92) of patients in the control group had 0-2 risk factors. Whereas
in the thrombocytopenia group, all patients had risk factors and 95.7%
(44/46) had 3 to 5 risk factors, only 4.4%(2/46) of patients had 0-2
risk factor. Conclusion: Tigecycline administration was associated with
thrombocytopenia. Health professionals should be aware of the
potentially severe tigecycline-associated thrombocytopenia and monitor
platelet count level, especially when the patients have more than 3 risk
factors.
Research on the response mechanisms of the Siberian crane population to hydrological temporal and spatial variations in transit stopover sites
Authors: Deng Guangyi , Zhu Shiying , Jiang Haibo , Gao Jin , Li Dehao , Wen Yang , Sheng Lianxi , He Chunguang , Cao Yingyue
Published: December 2022

The Siberian crane (Grus leucogeranus), a critically endangered species,
is used as an indicator species for ecosystem stability because of its
sensitivity to the environment. The distribution of Siberian cranes has
shown dramatic fluctuations on an order of magnitude at the main
stopover site (Jilin Momoge National Nature Reserve) since the present
century, which poses a great challenge to the conservation of endangered
species. Research on the threshold values of key factors of the Siberian
crane in stopover habitats and the relationship between the Siberian
crane and hydrological temporal and spatial fluctuations can promote
endangered species conservation. The response of population changes and
distribution patterns of Siberian cranes to hydrological temporal and
spatial patterns of wetlands was analyzed from 1984 to 2020. The results
showed that population changes and distribution patterns of Siberian
cranes were highly correlated with hydrological temporal and spatial
patterns in the study area, and their variation trend was the same.
However, there were obvious stage migration changes in the core activity
area of the Siberian crane (1984-2000, 2001-2010 and 2010-2020). The
habitat characteristics of fragmentation, dispersion and complex shape
of water bodies changed from steady to dramatic fluctuations and then
leveled off in the core activity area of Siberian cranes during the 37
years of migration transit. This was closely related to the early
agricultural reclamation and the later ecological water replenishment
project in the study area. In addition, the trend of the water pattern
index of the spatial distribution of Siberian crane active habitat was
also closely related to their habitat selection preference. When the
perimeter area fractal dimension of water (1.27-1.30), landscape
division index (0.73-0.95) and aggregation index (80.97-91.36) are
within a certain stable threshold, the stopover habitat of the Siberian
crane is suitable.
On definitions in mathematics
Authors: Sikic Zvonimir
Published: December 2022

The concept of definition is usually not covered in mathematical logic
textbooks. The definability of classes of structures is dealt with in model
theory but the definability of concepts within a given structure is not. Our
aim is to deal with these kind of definitions. We also address some of the
implications for teaching and learning mathematics.
Infinite triple series by integrals
Authors: Li Chunli , Chu Wenchang
Published: December 2022

A large class of infinite triple series are explicitly evaluated by computing
definite double integrals. Several remarkable formulae are presented in
terms of ? and ln 2.
Open Panentheism and "Creatio ex nihilo"
Authors: Clayton Philip
Published: December 2022

Open theism represents an important mediating position between more traditional or evangelical theology and process thought. But open theists have in general failed to engage panentheism. The increasingly significant role of panentheism not only in process thought but now across the theological spectrum—including among evangelical thinkers—suggests a new mediating position, open panentheism. Its panentheistic themes allow this new constructive theology to draw more deeply from process sources than most open theists do. At the same time, along with more traditional theologies, it affirms a free creation by God ex nihilo, and hence the free self-limitation (kenosis) of God in the creative act.
Some Reflections on the Relation Between Whitehead’s Process Philosophy and Gestalt Psychology
Authors: Riffert Franz , Bröderbauer Sandra , Huemer Michael
Published: December 2022

Although it is beyond doubt that there were historical connections between Whitehead and some of the proponents of Gestalt psychology, it is difficult to determine on the available body of historical evidence whether they were substantive or just marginal. A detailed comparison of Whitehead’s process metaphysics and the theories of Gestalt psychology is a task yet to be undertaken. Whitehead’s process philosophy and (some forms of) Gestalt psychology share basic similarities in their major principles. This is substantiated by two of Ehrenfels’ well-known gestalt qualities: (1) superadditivity, and (2) figure-ground relation. Both approaches can profit from one another: while Whitehead’s concept of consciousness and its interrelatedness with unconscious processes seems to be more elaborate, the Gestalt psychological approach, on the other hand, shows how these topics can be investigated by using experimental research designs. This is illustrated by an experiment on complex problem solving which demonstrates that unreportable (functionally unconscious) hints can improve even such sophisticated processes as complex problem solving. Since this is what should be expected from a Whiteheadian point of view, the results empirically confirm the process position on perception and thinking. Finally, further interesting possibilities of undertaking future empirical process research are outlined.
The ’Whitehead Century’ Revisited
Authors: Griffin David Ray
Published: December 2022

The present article is an attempt to update the author ’s article "Being Bold: Anticipating a Whiteheadian Century, " which appeared in Process Studies 31 (2002): 3-15. The earlier article was originally delivered at an International Whitehead Conference in 1998, whereas the present article was originally delivered as the banquet address at the International Whitehead Conference devoted to "Seizing an Alternative: Toward an Ecological Civilization" in 2015.
Whitehead and Ibn Arabi (1165-1240): Thoughts on Process and Sufi Metaphysics
Authors: Koca Ozgur
Published: December 2022

This study aims to critically compare and contrast the views of Ibn Arabi and Whitehead on God, the world, and the relationship between the two. I argue that there are significant overlaps in their systems that are sufficient to start a scholarly and enriching dialogue between the two thinkers. Both seem to envisage the world as a continuum of events, as a process. They also appear to agree that the primordial nature of God includes all potentialities that are also the metaphysical principles that ground regularity in a world that is otherwise defined by pure change. The concept of relationality lies at the core of their conception of the God-world relationship and of the relationship of entities with each other. We can also see an emphasis on God’s immanence without losing the distinction between God and the world. They both hold that God can be best understood by bringing antitheses together. They make similar distinctions between God’s primordial and consequent natures. The article also alludes to points of divergence between the two thinkers. These divergences do not exclude the possibility of a dialogue, but, in contrast, render the interaction between the two a meaningful and enriching one.
God For an Old Man
Authors: Dicken Thomas M.
Published: December 2022

This article consists in an autobiographical meditation on the Whiteheadian concepts of "linger" and "lure" as they relate to the past and future, respectively. It also examines the important experience of the presence of presence.
Language and Reality: Whitehead, Wittgenstein, and the Analytic
Authors: Gill Jerry H.
Published: December 2022

This article explores the relationship between Wittgenstein (both early and late) and Whitehead, specifically regarding the different views of the relationship between language and reality in these two thinkers.
The Virtues of Eclecticism
Authors: Fleischacker Samuel
Published: December 2022

Rawls and others have held that political agents in a liberal democracy should argue for their positions without adverting to religious grounds. I suggest here that this is because moral chims in general should not be grounded in religious views. Morality, I argue, consists in norms and ideals that can be defended from many different comprehensive views of the good life, not from any single one (whether that single view be religious or not). It follows that politics, even insofar as it is a sub-domain of morality, need not and should not depend on religion.
On the Question of Democracy
Authors: Gamwell Franklin I.
Published: December 2022

Persisting discussion, in both the academy and the wider public, about how democracy properly relates to religion is confused. All agree that religious freedom is required, but each of its two principal interpretations, separationist and religionist, commends itself by disclosing the other’s problems. Debate between the two is a standoff because both commonly assume that religions, in the sense protected by religious freedom, are or must be treated politically as immune to argumentative assessment. A third alternative is here proposed: religious freedom presupposes that religions or comprehensive assessments answer a rational question, and democracy is constituted as a full and free political discourse among them in order that governing decisions might be consistent with a valid understanding of the common good.
Depth Experience and Moral-Political Reflection
Authors: White Stephen K.
Published: December 2022

How should inquiry into ethical-political life come to terms with "depth experience"? I mean by this extraordinary experience that breaks into th familiar frames of meaning and reasoning that undergird everyday life, bringing some sort of transformation of commitments or identity. I speculate broadly about such experience, expanding the focus beyond theistic experiences, such as being "born-again. " When one does this, depth experience need not be thought, as it often is, anathema to political theory. I show rather that it can be cultivated so as to animate an admirable "bearing" on the part of citizens of affluent, latemodern societies.
The Perspectivity of Feeling: Process Panpsychism and the Explanatory Gap
Authors: Barrett Nathaniel F.
Published: December 2022

For mainstream analytic philosophy of mind, the exphnatory gap between first- and third-person accounts of consciousness derives from the inaccessibility of special, "experiential" properties of conscious minds. Within this framework, panpsychism is simply the claim that these special properties are everywhere. In contrast, process panpsychism understands the explanatory gap in terms of the particularity of feeling. While the particularity of feeling cannot be captured by third-person accounts, for this very reason it is amenable to understanding consciousness as an evolutionary process. Thus it may turn out that the elusiveness of feeling is essential to its functionality.