bluuebunny/crossref_metadata_2025 huggingface dataset:
Psychosocial impact of chronic otitis media on quality of life – A review
Authors: Swain Santosh Kumar
Published: October 2023

Due to several unpleasant symptoms that reduce people’s quality of life (QOL), chronic otitis media (COM) is considered a serious illness. Clinical signs of COM include hearing loss, otorrhea, ear fullness, ear discomfort, headache, and frequent tinnitus. COM is probably a trigger for the emergence of psychological issues and chronic stress. In addition, the inability to converse due to hearing loss is a limitation. The QOL is impacted in COM with hearing loss. Disabling hearing loss can have a significant effect on daily activities. For children to develop speech and language, proper hearing is necessary. Adults with hearing problems may have trouble finding work. Health-related QOL is an ever-increasing entity in health parameters. There is very little research done on COM and its psychosocial impact on QOL. This review article focuses on the psychosocial impact of QOL among patients with COM. This review article discusses epidemiology, COM, QOL, and their impact on patients in different age groups.
How to write a thesis protocol?
Authors: Rastogi Amit
Published: October 2023

The thesis is the beginning of the research by any medical student. A thesis protocol is an important document that illustrates the plan and methodology for any research study. It serves as a template for the researcher and ensures that the study is done ethically and systematically. A systematically written protocol helps the researcher to plan, execute, and complete the study with reproducible results. Understanding all its components is essential for starting the research journey. A well-written thesis protocol must cover all essential aspects of study planning, including the study’s objective, design, data collection tools, statistical analysis, and ethical procedures. This review article has been written by selecting and extracting data from online search engines such as Google and Bing and manual extraction of data from online articles available in PubMed and standard textbooks.
Primary hepatoid adenocarcinoma of lung: A rare malignancy mimicking tuberculosis
Authors: Singh Ranvijay , Aggarwal Sunita , Verma Abhishek , Sakhuja Puja , Nandi Sudipta , Garg Kamal
Published: October 2023

Hepatoid adenocarcinoma of lung (HAL) is a rare aggressive malignant tumour which histologically resembles hepatocellular carcinoma (HCC). Hepatoid adenocarcinoma (HAC) mostly produces high levels of alphafetoprotein (AFP) and is frequently found in extrahepatic organs including stomach, testes, ovaries, lungs and pancreas. Our patient was a male in his 40s with a chronic smoking history, presented with complaints of fever, weight loss, cough and anorexia for one month. On the basis of history, examination and initial investigation patient were started on empirical antitubercular therapy. However, within a span of 10 days, patient's condition worsened, and he developed a pulmonary embolism, which despite adequate treatment did not improve and the patient succumbed to his illness. Postmortem biopsy revealed a rare primary lung tumour, HAL.
How do parents of wheezing children report their symptoms? A single centre cross-sectional observational study
Authors: Paranjpe Mugdha Deepak , Sane Sudhir Vinod
Published: October 2023

Background:

Reported wheeze is of major relevance in the diagnosis and management of asthma and epidemiological studies on asthma prevalence. Our aim was to investigate the understanding of this term by parents and how they reported it to clinicians.

Methods:

A single-centre cross-sectional observational study was carried out at a tertiary care hospital. Parents of wheezing children self-completed a written questionnaire, which was analysed to understand parental understanding of the term wheeze and the main symptoms noticed by them. Their responses were compared to the operational definition used in the ISAAC study.

Results:

Questionnaires from 101 parents were analysed, out of which 50 children had an audible wheeze and 51 had an auscultatory wheeze. In our study, when asked about the main thing they noticed, 90 parents (89%) used non-auditory cues to identify wheeze, with the main presenting complaint being cough (n = 43, 42.6%), and only 4 (4%) reported wheezing. Even among the audible wheezers, only 7 (14%) used an auditory cue (alone or with some other cue) to describe their child's symptoms. Forty-seven parents knew the term wheeze, of which 19 parents (18.8%, N = 101) localised it to the chest, matching the epidemiological definition used in the ISAAC study.

Conclusion:

The word wheeze was not commonly used to describe a child's symptoms in our setting, even when the child was actively wheezing. Parents often use colloquial equivalents, nonspecific terms and other clinical cues such as coughing while reporting their child's symptoms. The parental concept of “wheezing” is different from epidemiological definitions.
Effects of thrombopoietin pre-treatment on peri-liver transplantation thrombocytopenia in a mouse model of cirrhosis with hypersplenism
Authors: Liu Zi-Rong , Zhang Ya-Min , Cui Zi-Lin , Tong Wen
Published: October 2023

Postcholecystectomy bile duct injury (BDI) remains a devastating iatrogenic complication that adversely impacts the quality of life with high healthcare costs. Despite a decrease in the incidence of laparoscopic cholecystectomy-related BDI, the absolute number remains high as cholecystectomy is a commonly performed surgical procedure. Open Roux-en-Y hepaticojejunostomy with meticulous surgical technique remains the gold standard surgical procedure with excellent long-term results in most patients. As with many hepatobiliary disorders, a minimally invasive approach has been recently explored to minimize access-related complications and improve postoperative recovery. Since patients with gallstone disease are often admitted for a minimally invasive cholecystectomy, laparoscopic and robotic approaches for repairing postcholecystectomy biliary stricture are attractive. While recent series have shown the feasibility and safety of minimally invasive post-cholecystectomy biliary stricture management, most are retrospective analyses with small sample sizes. Also, long-term follow-up is available only in a limited number of studies. The principles and technique of minimally invasive repair resemble open repair except for the extent of adhesiolysis and the suturing technique with continuous sutures commonly used in minimally invasive approaches. The robotic approach overcomes key limitations of laparoscopic surgery and has the potential to become the preferred minimally invasive approach for the repair of postcholecystectomy biliary stricture. Despite increasing use, lack of prospective studies and selection bias with available evidence precludes definitive conclusions regarding minimally invasive surgery for managing postcholecystectomy biliary stricture. High-volume prospective studies are required to confirm the initial promising outcomes with minimally invasive surgery.
Effect of low anterior resection syndrome on quality of life in colorectal cancer patients: A retrospective observational study
Authors: Jin Dong-Ai , Gu Fang-Ping , Meng Tao-Li , Zhang Xuan-Xuan
Published: October 2023

Postcholecystectomy bile duct injury (BDI) remains a devastating iatrogenic complication that adversely impacts the quality of life with high healthcare costs. Despite a decrease in the incidence of laparoscopic cholecystectomy-related BDI, the absolute number remains high as cholecystectomy is a commonly performed surgical procedure. Open Roux-en-Y hepaticojejunostomy with meticulous surgical technique remains the gold standard surgical procedure with excellent long-term results in most patients. As with many hepatobiliary disorders, a minimally invasive approach has been recently explored to minimize access-related complications and improve postoperative recovery. Since patients with gallstone disease are often admitted for a minimally invasive cholecystectomy, laparoscopic and robotic approaches for repairing postcholecystectomy biliary stricture are attractive. While recent series have shown the feasibility and safety of minimally invasive post-cholecystectomy biliary stricture management, most are retrospective analyses with small sample sizes. Also, long-term follow-up is available only in a limited number of studies. The principles and technique of minimally invasive repair resemble open repair except for the extent of adhesiolysis and the suturing technique with continuous sutures commonly used in minimally invasive approaches. The robotic approach overcomes key limitations of laparoscopic surgery and has the potential to become the preferred minimally invasive approach for the repair of postcholecystectomy biliary stricture. Despite increasing use, lack of prospective studies and selection bias with available evidence precludes definitive conclusions regarding minimally invasive surgery for managing postcholecystectomy biliary stricture. High-volume prospective studies are required to confirm the initial promising outcomes with minimally invasive surgery.
Analysis of textbook outcomes for ampullary carcinoma patients following pancreaticoduodenectomy
Authors: Zhang Xiao-Jie , Fei He , Guo Chun-Guang , Sun Chong-Yuan , Li Ze-Feng , Li Zheng , Chen Ying-Tai , Che Xu , Zhao Dong-Bing
Published: October 2023

Postcholecystectomy bile duct injury (BDI) remains a devastating iatrogenic complication that adversely impacts the quality of life with high healthcare costs. Despite a decrease in the incidence of laparoscopic cholecystectomy-related BDI, the absolute number remains high as cholecystectomy is a commonly performed surgical procedure. Open Roux-en-Y hepaticojejunostomy with meticulous surgical technique remains the gold standard surgical procedure with excellent long-term results in most patients. As with many hepatobiliary disorders, a minimally invasive approach has been recently explored to minimize access-related complications and improve postoperative recovery. Since patients with gallstone disease are often admitted for a minimally invasive cholecystectomy, laparoscopic and robotic approaches for repairing postcholecystectomy biliary stricture are attractive. While recent series have shown the feasibility and safety of minimally invasive post-cholecystectomy biliary stricture management, most are retrospective analyses with small sample sizes. Also, long-term follow-up is available only in a limited number of studies. The principles and technique of minimally invasive repair resemble open repair except for the extent of adhesiolysis and the suturing technique with continuous sutures commonly used in minimally invasive approaches. The robotic approach overcomes key limitations of laparoscopic surgery and has the potential to become the preferred minimally invasive approach for the repair of postcholecystectomy biliary stricture. Despite increasing use, lack of prospective studies and selection bias with available evidence precludes definitive conclusions regarding minimally invasive surgery for managing postcholecystectomy biliary stricture. High-volume prospective studies are required to confirm the initial promising outcomes with minimally invasive surgery.
Three-dimensional computed tomography reconstruction diagnosed digestive tract perforation and acute peritonitis caused by Monopterus albus: A case report
Authors: Yang Jin-Han , Lan Jin-Ying , Lin An-Yuan , Huang Wei-Biao , Liao Jin-Yuan
Published: October 2023

Postcholecystectomy bile duct injury (BDI) remains a devastating iatrogenic complication that adversely impacts the quality of life with high healthcare costs. Despite a decrease in the incidence of laparoscopic cholecystectomy-related BDI, the absolute number remains high as cholecystectomy is a commonly performed surgical procedure. Open Roux-en-Y hepaticojejunostomy with meticulous surgical technique remains the gold standard surgical procedure with excellent long-term results in most patients. As with many hepatobiliary disorders, a minimally invasive approach has been recently explored to minimize access-related complications and improve postoperative recovery. Since patients with gallstone disease are often admitted for a minimally invasive cholecystectomy, laparoscopic and robotic approaches for repairing postcholecystectomy biliary stricture are attractive. While recent series have shown the feasibility and safety of minimally invasive post-cholecystectomy biliary stricture management, most are retrospective analyses with small sample sizes. Also, long-term follow-up is available only in a limited number of studies. The principles and technique of minimally invasive repair resemble open repair except for the extent of adhesiolysis and the suturing technique with continuous sutures commonly used in minimally invasive approaches. The robotic approach overcomes key limitations of laparoscopic surgery and has the potential to become the preferred minimally invasive approach for the repair of postcholecystectomy biliary stricture. Despite increasing use, lack of prospective studies and selection bias with available evidence precludes definitive conclusions regarding minimally invasive surgery for managing postcholecystectomy biliary stricture. High-volume prospective studies are required to confirm the initial promising outcomes with minimally invasive surgery.
Mucocutaneous ulcer positive for Epstein–Barr virus, misdiagnosed as a small bowel adenocarcinoma: A case report
Authors: Song Ji Hyeong , Choi Ji Eun , Kim Jin Soo
Published: October 2023

Postcholecystectomy bile duct injury (BDI) remains a devastating iatrogenic complication that adversely impacts the quality of life with high healthcare costs. Despite a decrease in the incidence of laparoscopic cholecystectomy-related BDI, the absolute number remains high as cholecystectomy is a commonly performed surgical procedure. Open Roux-en-Y hepaticojejunostomy with meticulous surgical technique remains the gold standard surgical procedure with excellent long-term results in most patients. As with many hepatobiliary disorders, a minimally invasive approach has been recently explored to minimize access-related complications and improve postoperative recovery. Since patients with gallstone disease are often admitted for a minimally invasive cholecystectomy, laparoscopic and robotic approaches for repairing postcholecystectomy biliary stricture are attractive. While recent series have shown the feasibility and safety of minimally invasive post-cholecystectomy biliary stricture management, most are retrospective analyses with small sample sizes. Also, long-term follow-up is available only in a limited number of studies. The principles and technique of minimally invasive repair resemble open repair except for the extent of adhesiolysis and the suturing technique with continuous sutures commonly used in minimally invasive approaches. The robotic approach overcomes key limitations of laparoscopic surgery and has the potential to become the preferred minimally invasive approach for the repair of postcholecystectomy biliary stricture. Despite increasing use, lack of prospective studies and selection bias with available evidence precludes definitive conclusions regarding minimally invasive surgery for managing postcholecystectomy biliary stricture. High-volume prospective studies are required to confirm the initial promising outcomes with minimally invasive surgery.
Analysis of Judges' Considerations in Cases of Murder Based on Infidelity
Authors: Sidiq Fahmi , Ibrahim Riza Andrian , Binti Abdullah Suhaimi Nurnisaa
Published: October 2023

This study discusses the judge's consideration in deciding the criminal case of murder based on infidelity based on the judge's consideration of Article 338 of the Criminal Code Decision Number 88/Pid.B/2022/PN. The research uses normative juridical methods by examining primary and secondary legal materials. The results showed that the judge's consideration included both juridical and non-juridical aspects that influenced the final decision. The defendant is considered accountable for his actions, taking into account various factors such as the confession of guilt, the defendant's attitude in the trial, and previous legal experience. In addition, the defendant's actions and their impact on victims and society are also important factors in the judge's deliberations.
TRADITIONAL KNOWLEDGE OF CANCER TREATMENT IN SOUTHWESTERN NIGERIA: AN ETHNOPHARMACOLOGICAL REVIEW
Authors: Akinwumi I. A. , Ambali O. A.
Published: October 2023

Cancer is one of the main causes of death globally and a serious public health problem. One in every six mortalities worldwide is caused by cancer. Several chemotherapeutic medications are used to treat cancer without any selectivity, which has long-lasting negative consequences. Nigerian Medicinal Plants (NMPs) have been used in traditional and folk medicine to manage and treat cancer. The present review aims to provide a summary of the traditional knowledge of cancer treatment in Southwestern Nigeria detailing the plants, phytochemistry, the synergistic effects of synthetic and natural product drugs, the perspective of the indigenous people in the treatment of cancer, and the anticancer activity of Nigerian medicinal plants that have undergone empirical investigation. Some of these plants have been reported to exhibit anticancer activity in the breast, lung, pancreatic, stomach, colon, prostate, leukemia, ovarian, and cervical indicating the possible use of these medicinal plants as anticancer drug agents.
Structural simulations predicting protein folding in Alzheimer’s disease
Authors:   Ionian University, Department of Informatics, Bioinformatics and Human Electrophysiology Laboratory, Corfu, Greece, Krokidis Marios , Vrahatis Aristidis ,   Ionian University, Department of Informatics, Bioinformatics and Human Electrophysiology Laboratory, Corfu, Greece, Dimitrakopoulos George ,   Ionian University, Department of Informatics, Bioinformatics and Human Electrophysiology Laboratory, Corfu, Greece, Skolariki Konstantina ,   Ionian University, Department of Informatics, Bioinformatics and Human Electrophysiology Laboratory, Corfu, Greece, Vlamos Panagiotis ,   Ionian University, Department of Informatics, Bioinformatics and Human Electrophysiology Laboratory, Corfu, Greece, Exarchos Themis ,   Ionian University, Department of Informatics, Bioinformatics and Human Electrophysiology Laboratory, Corfu, Greece
Published: October 2023

Proteins assume a suitable spatial structure to effectively execute their intracellular functions. The occurrence of protein misfolding, resulting from single point mutations or external influences, along with the consequent buildup of protein aggregates, can lead to diverse pathological processes like neurodegenerative disorders. Protein misfolding serves as a risk indicator for Alzheimer’s disease (AD), the prevailing cause of neurodegenerative dementia in the elderly, characterized by gradual cognitive impairment. Several structure prediction algorithms and computational approaches have been developed to address this challenge. The present work focuses on specific proteins related to AD and aims to verify their conformation through ColabFold which utilizes the MMseqs2 algorithm to quickly provide multiple sequence alignments. The predicted models were then compared to selected PDB structures, a superposition was created and the TM-score and RMSD metrics were assessed. In addition, a comprehensive look into the superposed structures was performed to observe any potent deviations between pairs of residues. These notable findings encompass precise direct sequence-to-structure patterns found in individual AD polypeptides motifs and well-folded domains.
Human Capital and Innovation Nexus in India: Evidence from Simultaneous Equation Modelling
Authors: Mehra Kishor
Published: October 2023

"Using a simultaneous equation model, the present study attempts to empirically, investigate the interrelationship between human capital and innovation in Indian context. The study is conducted by taking all the 36 Indian states and Union territories into consideration from a regional perspective, focusing mainly on the quantification of the factors used. Since the simultaneous equation model is often subject to the problem of simultaneous bias and endogeneity, instrumental variable method using Two Stage Least Squares (2SLS) has been utilised to overcome the issue. In fact, the 2SLS provides the evidence of bidirectional spatial causality between human capital and innovation for Indian states, which holds significant policy implications for the country. Given a large demographic dividend in the form of highest working age population in the world, India could reap its benefits by promoting investments in the soft infrastructure such as health, education, and labour skills. This could help to boost its economic growth in the long run."
State Policy in the Sphere of Ensuring Economic Security: Management Aspect
Authors: Rozumenko Svitlana
Published: October 2023

"It is shown that the problem of forming the policy of economic security requires study in connection with the need to improve the theory and practice of the formation of state economic policy, as well as the study of certain problems related to the peculiarities of the functioning of the mechanism for ensuring economic security. Modern economic policy, guided in most cases by the provisions of neoclassical economic theory, in particular the monetarist theory of state influence on the economy, is not always effective enough, and state failures are becoming increasingly more frequent when various deviations of the actual conditions of economic development from classical models occur, which is especially obvious at present, with the increasing influence of the factor of geopolitics and geoeconomics on the economic security of states."
Socio-economic Aspect of territorial Organization of Power
Authors: Zagorsky Volodymyr
Published: October 2023

"In the article, theoretical aspects of territorial organization of power are considered, as well as examples of practical implementation of appropriate concepts and approaches. Actual and potential pitfalls are considered, based on specific examples, in particular, on the example of gentrification in the United States. The main provisions of the most advanced methodological approaches to strategic planning of social and economic aspects of territorial development, as a function of territorial power, are systematized"
Reformation Public Administration in Ukraine in the Context of European Integration: Current State, Problems and Priorities
Authors: Goncharuk Nataliia
Published: October 2023

"The research is focused on the problem of reforming public management in Ukraine. An analysis of the current state of reforming public management in Ukraine has been carried out. It has been substantiated that the reformation of public administration and local self-government should be carried out in accordance with European standards and democratic governance principles. The legal framework for reforming public administration and local self-government has been analyzed. It has been emphasized that the current state of development of Ukrainian legislation in this area requires a critical rethinking of the existing norms, overcoming contradictions and inconsistencies between them and indicates the need to adopt a number of new legislative acts. The analysis of the current state of reforming public management in Ukraine has shown that most public authorities have been formed in independent Ukraine; there were changes in organizing the work of the Cabinet of Ministers of Ukraine, central and local executive authorities, and the system of local self-government bodies; the processes of modernizing the public service are underway; a number of positive steps have been taken towards reforming public administration and local selfgovernment, and the decentralization reform was actively implemented in 2014-2021. The necessity of further optimization of the central executive authorities’ system, modernization of the public service and human resource management, and completion of decentralization processes was emphasized. The main provisions of the Strategy for Public Administration Reform of Ukraine for 2022-2025 and the Concept for Reforming Local Self-Government and Territorial Organization of Power in Ukraine were analyzed, as well as other strategic and conceptual documents adopted in Ukraine for the purpose of implementing public management reform. The theoretical construction of a new model of public management based on European principles and standards has been substantiated. Strategic priorities for reforming public management in Ukraine in the context of European integration have been identified."
Quality Management Strategies in the Hotel and Restaurant Industry: best Practices and Challenges
Authors: Banyeva Iryna
Published: October 2023

"The article is devoted to the study of the system of personalized service in the field of hospitality as its competitive advantage in terms of quality in the conditions of functioning in the modern market. The specifics of competition and the transformation of consumer demand in the area under study are considered, and a positive impact of the service model on the efficiency on the business is highlighted. It is shown that the best results are achieved through a model of customer data personalization that is different from competitors and its use in a well-thought-out strategy. At the same time, an effective personalized service system requires continuous investment to maintain and grow valuable data, including with the use of AI and ML."
Determinants of Capital Formation in Agriculture: A Case Study of Dimapur District of Nagaland, India
Authors: Longkumer Sungjeminla
Published: October 2023

"The formation of capital through investment in agriculture helps build up the stock of capital assets and resources that enable the farmers to utilize their resources, particularly land and labour, more efficiently. The present study includes a total sample of 200 farm households consisting of marginal, small, medium, and large farmers from Dimapur District of Nagaland, selected through a three-stage stratified sampling technique for the year 2020-21. Using multiple regression technique assessed the factors that affect the capital investment at the farm level. The coefficient of determinant (R2) value reveals that the model as good fit. Many factors influence the formation of capital in agriculture, among which family income (in `), working members (in number), and cropping intensity (in %) have positive influence. Unlike popular studies, the operational holding (in acres) has shown negative influence. Further, the age and education of the head of a family show no influence. There is a pressing need for fundamental change in the strategy to raise the resources and income of the farmer and accordingly accelerate the pace of capital formation in agriculture through targeting investment in irrigation, land development, and other infrastructure development."
Intra-Industry trade in Manufactured Goods between India and Select Southeast Asian Nations: An Empirical Examination using the G-l Index
Authors: Khalid Nikhat
Published: October 2023

"Post the wave of industrialisation, a new order of world trade emerged, which could not be explained by the classical and neoclassical models of trade. Such a trade pattern came to be denoted as ‘Intra- Industry-Trade’(IIT), implying exchange of similar or identical goods and services within an industry or sector between countries. The ASEAN is India’s fourth largest trading partner, and their economic partnership has been growing exponentially. A high degree of IIT exists in India-ASEAN trade. The present study undertakes a comprehensive examination of IIT in manufactures between India and top five trade partners among ASEAN, i.e., Indonesia, Malaysia, Singapore, Thailand, and Vietnam during the period 1992-2020. As manufactures comprise of the most traded category between India-ASEAN, Intra-Industry trade is examined at technology level, wherein manufactures are classified into resource based, low, medium, and high technology manufactures, and at commodity category level, wherein IIT is examined based on major manufactured categories. The analysis reveals exponential increase in India’s IIT among manufactured goods with the select ASEAN countries from 1992 to 2020. Albeit the degree of IIT varies by country, which has been examined in detail. The study suggests the promotion of IIT between the partner countries such that the several benefits of IIT can be harnessed, such as, efficiency gains, improved competitiveness, increased productivity, and greater economic growth, which would be mutually advantageous to India and ASEAN countries. Top of Form"
Prediction of the Exchange Rate of India Considering a Causal Relationship with Crude Oil Consumption
Authors: Pundhir Shiv Kumar Singh
Published: October 2023

"A good prediction of the exchange rate is crucial in the economy. Exchange rate variations highly affect the economy of a country. Over time, so many methods were adopted to predict exchange rates. In this work,data on crude oil consumption and exchange rate from 1992 to 2021 is analyzed. The causal relationship between the exchange rate of India with crude oil consumption of India is tested using the Granger Causality test. To predict the exchange rate of India a causal model is developed. The crude oil consumption of India is predicted for 2020 to 2040 using HoltWinters and ARIMA models. Since the forecast accuracy of the ARIMA model is found good so the ARIMA model is used to predict the crude oil consumption of India. Predicted values of the crude oil consumption of India for the years 2030 and 2040 are found 6.018 and 7.261 million barrels per day respectively. These values are used for the regression model to predict the exchange rate of India. So the exchange rate of India for 2030 and 2040 will be 82.57 and 96.33 US dollars respectively."
Intervention strategies to implement a preventive conservation and maintenance plan in concrete buildings in the modern period of Bogotá
Authors: Corzo Sergio Adrián Garcés , Moreno Florinda Sánchez , Bayona Francisco Javier Lagos , Ruiz Juan Andrés Barbosa
Published: October 2023

Reinforced concrete was the material of choice for many architects of the modern era, exploiting the material in a multitude of creative and innovative ways. Many of the most extraordinary structures of the modern era demonstrate the potential of reinforced concrete and illustrate the rapid evolution of the material throughout the 20th century. It is the most used material in the construction industry due to its high resistance and its ease of molding when it is prepared, it also contains steel in the form of rod and wire, with a useful life of its components, built as a system, for more of one hundred years as long as they are well designed, well built and above all they are given adequate maintenance. However, the durability of concrete structures depends on several main environmental factors, the quality of the raw material and its maintenance. Some of the studies and research projects on the subject of Concrete focus on the historiography of reinforced concrete in Colombia, where some authors highlight aspects of construction processes, technical innovations, construction companies, and architecture and engineering projects that were pioneers in the 20th century. In Colombia, a historical context of this material and the most representative projects in the city of Bogotá, Colombia are detailed below.
Peningkatan Hasil Latihan Passing dalam Permainan Sepak Bola Menggunakan Metode Drill pada Atlet SSB Perseta
Authors: Pangestoe Aldhi Dimas , Yono Topo , Eurika Novy
Published: October 2023

Football is a popular game involving two teams with 11 players on each team. This game requires players to use their foot skills to compete for the ball and score goals in the opponent's goal. Basic techniques in football include passing the ball, dribbling, ball control, and heading the ball. Programmed, routine, and disciplined training is essential to master these basic techniques. Passing in football involves transferring the ball from one player to another within the same team. Passing skills are crucial in the game because their purpose is to create space, score goals, maintain defense, and restart the ball after a foul. The inside of the foot is often used in passing because it is wider and allows players to direct the ball more accurately. Drill methods, which involve systematically repeating movements, can help improve mastery of basic techniques. Drill training can also enhance physical conditioning. This research aims to improve passing training outcomes for Perseta SSB athletes using the drill method. This study benefits researchers, athletes, coaches, and others in enhancing understanding and skills in football passing. The method used in this research is the sports action method. The results obtained indicate that passing training using the drill method, especially the triangle drill method, is effective in improving athletes' passing abilities. This training helps improve coordination, speed, and passing accuracy. This finding provides evidence that drill methods can be used as an effective approach in training passing techniques and skills for athletes.
The Effect of Weight Training on the Kicking Ability of Female Soccer Players in Jember
Authors: Fitriani Siti Dwi , Apriliyanto Rizki , Hardovi Bahtiar Hari
Published: October 2023

Abstract: The development of soccer in the world is rapidly advancing, driven by increasingly advanced technology, pushing the world of soccer towards a more modern direction. Soccer has become the most popular sport globally, a sport that can be played by people of all ages and genders. The public's interest in soccer knows no boundaries; anyone can play it. While soccer is predominantly played by men, it is also a sport that can be played by women. Women's soccer in Indonesia is gaining popularity, even though not many women participate in it. Jember Putri is one of the women's soccer clubs in Jember. Improving the athletes' abilities must be carefully considered to enhance the skills and physical endurance of each individual. There are many methods that can be used in athlete development, one of which is weight training.
Evaluation of Mirna-155 and Mirna-223 in Blood in Patients with Ulcerative Colitis
Authors:   Department of Biology, College of Science, University of Al-Qadisiyah / Iraq, Abdul-Aali Taqwa Saoud
Published: October 2023

Ulcerative colitis is common and complex conditions that are difficult to cure. MiRNAs are a class of small, non-coding, single-stranded RNA molecules which play a key role in autoimmune and inflammatory diseases especially in IBD. Despite the efficacy of biological treatment, a significant proportion of patients with IBD do not show an adequate response. For this reason it is crucial to identify biomarkers useful to predict clinical response. In present study, we aimed to evaluate the microRNA-155 (miR-155) and microRNA-223 (miR-223) as prognostic marker in disease response to therapy in patients with UC. This study included 80 patients with UC (40 patients who response to conventional treatment and 40 who resist and they are on biological treatment) and 40 healthy controls. Real-time polymerase chain reaction (RT-PCR) assay was performed for evaluation miRNA-155 and miRNA-223. According to the results of this study, There was significant variation in mean fold change of miR-155 among groups (p <0.001), the level was highest in patients on conventional treatment followed by patients on biological therapy and then by control group. With respect to miR-223, the difference in mean fold change was significant among study groups (p <0.001), the level was highest in patients on biological treatment followed control group and then by patients on conventional therapy. Receiver operator characteristic (ROC) curve analysis was carried, the cutoff value of miRNA-155 was ≤1.43 with 20 % sensitivity level, 95 % specificity level and 53.3% accuracy level. The cutoff vale of miRNA-223 was >4.51with 25 % sensitivity level, 92.5% specificity level and 59.1 % accuracy level. In conclusion, this study have evaluated the therapeutic response to corticosteroid, or IFX therapy and blood expression of miRNA by screening the responses to anti-TNF-α and conventional therapy, this study demonstrated that the level of miRNA-223 associated with the response to IFX which is highly increased in biological therapy (negative response) comparing to the conventional therapy (positive response) group after IFX therapy while the present study demonstrated that miRNA-155 fold change upregulated in patients with ulcerative colitis and on conventional therapy (positive response) in comparison with healthy control group.
The Potential Role of Kecombrang (Etlingera Elatior) Extract in Wound Management: A Review on its Anti-Oxidative, Anti-Inflammatory, Antimicrobial, and Anti-Melanogenesis Effects
Authors:   Department of Surgery, University of Jenderal Soedirman - Margono Soekarjo County Hospital, Indonesia, Fawzy Ahmad
Published: October 2023

Wound healing is a complex process critical for tissue repair post-injury. Botanicals, renowned in traditional medicine, hold potential in wound healing due to their bioactive compounds. Etlingera elatior, a Zingiberaceae family member, is attracting attention for its diverse medicinal properties. Indigenous to Southeast Asia, it has been traditionally used for wound care, attributed to its anti-inflammatory, antioxidant, and antimicrobial effects. Recent scientific investigations highlight its ability to promote tissue repair, diminish inflammation, and counteract oxidative stress. These findings position Etlingera elatior as a promising candidate for wound healing management, particularly in plastic surgery. However, its clinical translation faces challenges, including limited clinical trials and mechanistic understanding, necessitating standardized extraction methods and regulatory approval. Bridging the gap between botanical therapies and clinical use requires robust clinical trials, mechanistic studies, and formulation optimization. Collaboration among researchers, clinicians, and regulators is pivotal in realizing Etlingera elatior's wound healing potential.
Surgical Management of Trichoepithelioma: A Case Report
Authors:   Department of Plastic Surgery, Faculty of Medicine University of Jenderal Soedirman - Margono Soekarjo County Hospital, Indonesia, Fawzy Ahmad
Published: October 2023

Introduction: Trichoepithelioma is a rare benign tumor, predominantly found on the face and scalp, with an unclear prevalence in general population. Low incidence and lack of evidences, made trichoepithelioma management still a controversial domain in dermatology. Case: This study presented a 31-year-old woman with extensive trichoepithelioma on her nose, who underwent surgical excision and full-thickness skin grafting Result: Patient showed satisfaction with favorable aesthetic result and the consequent improvement in quality of her daily life. Discussion: Nasal intricate anatomy poses specific challenges in managing tumor like trichoepithelioma, emphasizing the importance of careful surgical planning. Surgical excision, Mohs surgery, and laser ablation are viable options, while non-surgical treatments such as topical therapies and cryotherapy are effective for superficial lesions. Patient satisfaction and quality of life are essential considerations, requiring open communication and psychological support. Emerging techniques, including advanced imaging, 3D bioprinting, and targeted molecular therapies, hold promise for optimizing trichoepithelioma management. Personalized approaches based on genetic profiling and collaborative research efforts are avenues for future exploration. Conclusion: Surgical management of trichoepithelioma on the nose, while challenging due to aesthetic concerns, can yield favorable outcomes. The approach to trichoepithelioma management should consider lesion size, surgical and non-surgical options and preference of the patient. Proper excision and meticulous skin grafting may provide aesthetically pleasant result. Personalized care, including psychological support, is crucial for post-surgery patient satisfaction. Multidisciplinary collaboration optimizes patient care in these unique cases.
Müllerian Agenesis and Beyond: A Comprehensive Analysis of Rokitansky-Küster-Hauser Syndrome
Authors:   Universidad Autónoma de Guadalajara. Guadalajara, Jalisco, México., Fernández Rebeca Álvarez , Mexicano Abril Mariana Abraham ,   Universidad de Guanajuato. Guanajuato, México., Bautista Perea Emmanuel ,   Universidad Nacional Autónoma de México. Facultad de estudios Superiores Iztacala., González Solís Blanca Areni ,   Universidad del Valle de México. Campus Reynosa., Martínez Imanol Guadalupe ,   Instituto Politécnico Nacional, Escuela Superior de Medicina., Montoya Luis Enrique Morales ,   Universidad Autónoma de Sinaloa, Culiacán, Sinaloa. México
Published: October 2023

Rokitansky-Küster-Hauser syndrome (RKH), also known as Müllerian agenesis, represents a rare congenital disorder characterized by the absence or underdevelopment of the müllerian duct structures in phenotypic females. This condition manifests as primary amenorrhea, with a typical constellation of associated anomalies encompassing the urogenital and skeletal systems. Despite its rarity, RKH poses significant physical, psychological, and reproductive challenges to affected individuals. This comprehensive article endeavors to elucidate the complex clinical spectrum, pathogenesis, diagnostic modalities, and multidisciplinary management strategies for Rokitansky-Küster-Hauser syndrome.
Criminal Liability of Illegal Parking Attendants (Study in Jayapura City)
Authors:   Faculty of Law, Cenderawasih University, V. Novana, , Kareth J ,   Faculty of Law, Cenderawasih University, Thesia Elias Hence ,   Faculty of Law, Cenderawasih University
Published: October 2023

This research departs from the widespread problems regarding illegal parking in Indonesia, especially in the city of Jayapura. The problem is then formulated into a problem formulation, namely what is the criminal responsibility of illegal parking attendants in Indonesia, using the example of a study in the city of Jayapura. The research method used in this paper is to use an empirical juridical legal approach. The results of the study show that parking attendants are subjects who commit illegal parking crimes which are a form of illegal levies. For illegal parking crimes committed by illegal parking attendants, they can be subject to Article 368 of the Criminal Code, Article 373 of the Criminal Code and Article 379 of the Criminal Code. The criminal responsibility of illegal parking attendants is the responsibility imposed on a person who carries out illegal parking activities. The types of criminal sanctions that can be imposed on illegal parking attendants are imprisonment or fines.
The Influence of Job Satisfaction and Work Environment on Employee Performance through Organizational Citizenship Behaviour on BKPSDM of Malang District Government
Authors:   Student of Postgraduate Magister Management, University of Merdeka Malang, Indonesia, Andriani Feriska , Sumarsono Tanto G. ,   Faculty of Economics and Business, University of Merdeka Malang, Indonesia, Sunardi Sunardi ,   Faculty of Economics and Business, University of Merdeka Malang, Indonesia
Published: October 2023

All organizations expect to have human resources (HR) who have good performance to achieve the goals of an organization. Employee performance is influenced by several factors, such as job satisfaction, work environment, and organizational citizenship behaviour (OCB). This study aims to analyze the effect of job satisfaction and work environment on employee performance through Organizational Citizenship Behaviour at BKPSDM Malang Regency Government. This quantitative research obtained a sample of 81 respondents with a saturated sampling method. The data analysis technique used is descriptive analysis, classic assumption test, t-test, and path analysis. The results of the study concluded that job satisfaction and work environment significantly affect organizational citizenship behaviour; job satisfaction and work environment do not affect employee performance; organizational citizenship behaviour affects employee performance. The mediation results show that organizational citizenship behaviour can mediate the effect of job satisfaction and work environment on employee performance.
Analysis of Risk Components of Building Construction Projects in Construction Companies: Case Study of Projects in Jabodetabek
Authors:   Magister Management, Universitas Kristen Indonesia, Suharno Suharno , S.Legowo Poerwaningsih ,   Magister Management, Universitas Kristen Indonesia
Published: October 2023

Risk management is very important for a construction company to carry out all company activities and especially to run a construction project. As is known, the project is carried out through stages in which it is very loaded with unwanted events, ranging from the tender process to get the project, the design stage, the pre-construction stage, the construction stage, and the post-construction stage. It is determined that risk categories are divided into operational; Financial; legal; & marketing. Causative factors consist of external; legal; human; process; & system. Areas of cause determined: design &; marketing; legal; implementation; therapy. Risk treatment strategies are determined: eliminating sources of risk; maintaining risk with the right decision; changing the possibilities; and Changing consequences. Based on secondary data obtained on seven projects that have been completed in the Jabodetabek area by one of the construction companies in Indonesia, qualitatively it was found that operational risk occupies the top position, the category that most often arises unwanted events. Process factors are the highest factors as the cause of an unwanted event. Process factors are the highest factors as the cause of an unwanted event. Then the construction period is the highest area, and often an unwanted event occurs. Naturally, the construction period has the longest duration compared to other stages. It further eliminates sources of risk, transforms consequences and turns possibilities into the most frequent ones in the process of managing risks in the project. Meanwhile, based on the level of risk identified from 38 risks that occurred in seven projects, the level of extreme risk occurred in as many as 10 events and as many as 19 events, then after follow-up, the level of extreme risk became as many as 2 events and high to 19 events, this indicates that these unwanted events affect the profit target of the project being worked on. Thus, ERM becomes very important for a construction company in order to achieve the company's goals and objectives and ERM is an important part of good corporate governance