bluuebunny/crossref_metadata_2025 huggingface dataset:
Extrema of the generalized allocation scheme based on $m$-dependent sequence
Authors: Miao Yu , Qu Xiaoming , Yang Guangyu
Published: April 2022

В статье получены асимптотические оценки для экстремумов в обобщенной схеме размещения, порожденной $m$-зависимыми случайными величинами. Полученные результаты позволяют перенести некоторые утверждения Чупрунова и Фазекаша ("Аналог обобщенной схемы размещения. Предельные теоремы для максимального объема ячейки", Дискрет. матем., 24:3 (2012), 122-129), с независимого случая на случай $m$-зависимых случайных величин.
О двух предельных значениях хроматического числа случайного гиперграфа
Authors: Demidovich Yurii Aleksandrovich , Shabanov Dmitry Aleksandrovich
Published: April 2022

Работа посвящена изучению предельной концентрации значений хроматического числа случайного гиперграфа $H(n,k,p)$ в биномиальной
модели. Доказано, что при фиксированном $k\ge 3$ и не слишком быстро растущем значении $n^{k-1}p$ хроматическое число гиперграфа $H(n,k,p)$ с вероятностью, стремящейся к $1$, принадлежит множеству из некоторых двух соседних значений. Кроме того, показано, что при чуть более сильных ограничениях на рост $n^{k-1}p$ данные значения можно отыскать явным образом как функции от $n$ и $p$.
Measured versus estimated creatinine clearance in critically ill patients with acute kidney injury: an observational study
Authors: Kadivarian Sara , Heydarpour Fatemeh , Karimpour Hasanali , Shahbazi Foroud
Published: April 2022

Background: Acute kidney injury (AKI) commonly occurs in critically ill patients. Estimation of renal function and antibiotics dose adjustment in patients with AKI is a challenging issue.Methods: Urinary creatinine clearance was measured in a 6-hour urine collection from patients with acute kidney injuries. The correlations between different formulas including the modified Cockcroft-Gault, modification of diet in renal disease, chronic kidney disease-epidemiology collaboration, Jelliffe, kinetic-glomerular filtration rate (GFR), Brater, and Chiou formulas were considered. The pattern of the prescribed antimicrobial agents was also compared with the patterns in the available resources.Results: Ninety-five patients with acute kidney injuries were included in the research. The mean age of the participants was 63.11±17.58 years old. The most patients (77.89%) were in stage 1 of AKI according to the Acute Kidney Injury Network criteria, followed by stage 2 (14.73%) and stage 3 (7.36), respectively. None of the formulations had a high or very high correlation with the measured creatinine clearance. In stage 1, Chiou (r=0.26), and in stage 2 and 3, kinetic-GFR (r=0.76 and r=0.37) had the highest correlation coefficient. Antibiotic over- and under-dosing were frequently observed in the study.Conclusions: The results showed that none of the static methods can predict the measured creatinine clearance in the critically ill patients. The dynamic methods such as kinetic-GFR can be helpful for patients who do not receive diuretics and vasopressors. Further studies are needed to confirm our results.
Bespoke particle shapes in granular matter
Authors: Cantor David , Cárdenas-Barrantes Manuel , Orozco Luisa Fernanda
Published: April 2022

Among granular matter, one type of particle has special properties. Upon being assembled in disordered configurations, these particles interlock, hook, almost braid, and – surprisingly, considering their relatively low packing fractions – show exceptional shear strength.Such is the case of non-convex particles. They have been used in the shapes of tetrapods, ‘L’, ‘Z’, stars, and many others, to protect coasts or build self-standing structures requiring no binders or external supports. Although these structures are often designed without a comprehensive mechanical characterization, they have already demonstrated great potential as highly resistant construction materials. Nevertheless, it is natural to attempt to find the most appropriate non-convex shapes for any given application. Can a particle shape be tuned to obtain a desired mechanical behavior? Although this question cannot be answered yet, current technological, simulation, and experimental developments strongly suggest that it can be resolved in the next decade. A clear understanding of the relationships between particle shapes, mechanical response, and packing properties will be key to providing insights into the behavior of these materials. Such work should stand on 1) robust and general shape descriptors that encode the complexity of non-convex shapes (i.e., the number of arms, the symmetries, and asymmetries of the bodies, the presence of holes, etc.), 2) the analysis of the response of assemblies under different loading conditions, and 3) the disposition and reliability of non-convex shapes to ensure durability. The manufacturing process and an efficient use of resources are additional elements that could further help to optimize particle shape. In the quest of designing bespoke non-convex particles, this paper consolidates the challenges that remain unresolved. It also outlines some routes to explore based on the latest developments in technology and research.
Evaluation of the Shapley Additive Explanation Technique for Ensemble Learning Methods
Authors: Assegie Tsehay Admassu
Published: April 2022

This study aims to explore the effectiveness of the Shapley additive explanation (SHAP) technique in developing a transparent, interpretable, and explainable ensemble method for heart disease diagnosis using random forest algorithms. Firstly, the features with high impact on the heart disease prediction are selected by SHAP using 1025 heart disease datasets, obtained from a publicly available Kaggle data repository. After that, the features which have the greatest influence on the heart disease prediction are used to develop an interpretable ensemble learning model to automate the heart disease diagnosis by employing the SHAP technique. Finally, the performance of the developed model is evaluated. The SHAP values are used to obtain better performance of heart disease diagnosis. The experimental result shows that 100% prediction accuracy is achieved with the developed model. In addition, the experiment shows that age, chest pain, and maximum heart rate have positive impact on the prediction outcome.
Troublemakers
Authors: Crossley Stephen
Published: April 2022

Paving the way for a government to fulfil its responsibility to families, this authoritative and critical account of the Troubled Families Programme reveals the inconsistencies and contradictions within it, and issues of deceit and malpractice in its operation.
Safeguarding Future Autonomous Traffic by Infrastructure based on Multi Radar Sensor Systems
Authors:   Technische Hochschule Ingolstadt, GERMANY, Egor Streck Egor Streck , Peter Schmok Peter Schmok ,   ADC Automotive Distance Control Systems GmbH (Continental), GERMANY, Klaus Schneider Klaus Schneider ,   Conti Themic microelectronic GmbH, GERMANY, Hueseyin Erdogan Hueseyin Erdogan ,   Conti Themic microelectronic GmbH, GERMANY, Gordon Elger Gordon Elger ,   Fraunhofer-Institut für Verkehrs- und Infrastruktursysteme IVI, GERMANY
Published: April 2022

"Due to its robust operation and high performance during bad weather conditions and overnight as well as the ability of using the Doppler Effect to measure directly the velocity of objects, the radar sensor is used in many application fields. Especially in automotive many radar sensors are used for the perception of the environment to increase the safety of the traffic. To increase the security level especially for vulnerable road users (VRU’s) like pedestrians or cyclists, radar sensors are used in driver assistance systems. Radar sensors are also used in the infrastructure, e.g. a commercial application is the detection of cars and pedestrians to manage traffic lights. Furthermore, radar sensors installed in the infrastructure are used in research projects for safeguarding future autonomous traffic. The object recognition and accuracy of radar-based sensing in the infrastructure can be increased by cooperating radar systems, which consist out of several sensors. This paper focus on the data fusion method of two radar sensors to increase the performance of detection and localization. For data fusion the high level cluster data of the two radar sensors are used as input data in a neuronal net (NN) structure. The results are compared to the localization obtained by using only a single radar sensor operating with an ordinary tracking algorithm. First, different models for chosen region of interests (ROI) and operating mode of cooperative sensors are developed and the data structure is discussed. In addition, the data are preprocessed with a coordinate transformation and time synchronization for both sensors, as well as the noise filtering to reduce the amount of clusters for the algorithm. Furthermore, three NN structures (CNN, DNN and LSTM) for static + dynamic objects and only dynamic objects are created, trained and discussed. Also, based on the results further improvements for the NN performance will be discussed."
Development of Multiple Predictive Gear Shifting System of Automatic Transmission Connected with Electronic Horizon
Authors:   Hyundai Motor Company, REPUBLIC OF KOREA, Jeon Byeong , Chai Min Jae ,   Hyundai Motor Company, REPUBLIC OF KOREA, Park Kwang Hee ,   Hyundai Motor Company, REPUBLIC OF KOREA
Published: April 2022

"In general, the most essential role of a transmission is to transmit the driving power of the power source to the wheel as much as possible without loss, and in this process, the operating point of the power device is controlled by shift schedule so that the driving efficiency can be maximized through appropriate gear shifting. Regardless of this driving efficiency of the power source, it often occurs that gear shifting can be helpful to the driving situation in the viewpoint of the driver's convenience. It refers to a case in which a rapid deceleration or acceleration must be prepared in advance depending on a specific driving event, such as winding road, downhill, speed bump or entering a highway and so on. In the case of an automatic transmission, the function of shifting to maximize the driving efficiency of the power source can be achieved according to the shift scheduling that has already been set to an optimum value. The automatic transmission, however, is likely to be more disadvantageous than a manual transmission in which the driver directly operates the gear position while observing the outside situation according to the approximate road shape and traffic flow. It is possible to realize an optimized predictive control system that enables early gear shifting of transmission in preparation for upcoming driving situations by connecting the transmission with the connectivity devices in the vehicle that provides various information of the road geometry and traffic conditions in front of the vehicle. In this study, we would like to introduce a new technologies of multiple predictive gear shifting control system and its application effect on the real road driving, that predicts at once the various driving situations expected to occur in the future and performs appropriate transmission gear before the situation by using electronic horizon including 3-dimentional map data and signals from front radar and camera equipped in the vehicle. The technology consists of following three steps: 'Situation Decoding Step' that converts the various raw signals from electronic horizon devices into a comprehensive driving situation that can be understandable to the transmission control unit, 'Speed Prediction Step' that determines the vehicle speed profile required for the upcoming driving situation, and 'Powertrain Control Step' that controls the most proper transmission gear and engine torque. The multiple predictive gear shifting system of automatic transmission proposed in this study was applied to mass production in Hyundai-Kia vehicles, and contributed not only to drivability, safety, and vehicle durability, but to improving fuel efficiency in real road driving."
Validation of a Data-Based Thermal Model of a Gearbox
Authors:   Forschungsinstitut für Kraftfahrwesen und Fahrzeugmotoren Stuttgart, GERMANY, Erwin Brosch Erwin Brosch , Daniel Trost Daniel Trost ,   FKFS.de, GERMANY
Published: April 2022

"Oil sump temperature in conventional gearboxes is one of the most important technical framework conditions in terms of research, development and especially in testing of gearboxes. Nevertheless, it is not always possible to set a suitable sensor or to access sensor data with sufficient quality. The need for a simulated oil sump temperature is, among others, for such purposes. In a previous work, an approach for this is presented. A thermal model of a gearbox is generally created on the basis of lumped-element models. Therefore, the thermal masses, such as oil, gears and the gearbox housing, are modeled as lumped-capacitance and the thermal transitions between them as thermal resistances. In addition, there are thermal sources due to heat generation and thermal sinks due to cooling. In principle, a high level of detailed knowledge would be required to parameterize this lumped-element model. To circumvent this, a data-based approach for parameter identification is chosen. For this purpose, an optimization problem is formulated which aims at minimizing the error between simulated and measured values. The methods of genetic algorithms are used to solve the optimization problem. This computationally expensive step is done in advance, apart from the actual use of the model. Thus, a model with little detailed knowledge and without extensive model building can be generated. The preliminary conceptual paper focusses on gearboxes of battery electric vehicle (BEV) with low thermal masses. In contrast, transmissions in conventional and in hybrid electric vehicles (HEV) are steadily increasing in size, number of gears, and thermal mass. The generality of the approach described above is shown by modeling a very large gearbox in the present work. For the specific case, even a gearbox with a coolant/oil heat exchanger is considered. Beside this extension of the model, the former approach has additionally been improved regarding the accuracy of the results. By varying the measured and simulated model inputs, the parameters can be determined more accurately. Furthermore, the final simulation model is upgraded with these additional model inputs as well, which leads to a significant improvement of the simulation results. The model complexity even decreases. These results base on a large measurement data set, which is necessary for the identification of the parameters. In addition, measurement data is needed for the validation of the method. An extensive series of measurements have been taken on an electric powertrain test bench and is presented within this work. Both, generic measurement runs, which are ideal for system identification, and runs similar to a real driving data were recorded."
Evaluation of a Serial-parallel Hybrid Powertrain Concept for a Heavy Duty Truck
Authors:   VKA / RWTH, GERMANY, Kossioris Theodoros ,   FEV Europe GmbH, GERMANY, Schaub Joschka , Ehrly Markus , Maiterth Johannes , Keizer Ruben , an der Put Dieter
Published: April 2022

According to latest European Union (EU) findings, CO2 emissions from heavy duty vehicles, including lorries, buses and coaches, account for about 6 % of the total CO2 emissions in the Union and to about 25 % of the total CO2 emissions from road transport. It is expected that without further measures, the share of CO2 emissions from heavy duty vehicles will increase by around 9 % between 2010 and 2030. The constant growth in demand for on-road transport underlines the urgency of cleaner and more fuel-efficient global on-road transport vehicles fleets. In February 2019, the EU finally decided to set CO2 limits for on-road commercial vehicles for the first time. Legislation requires a 15 % CO2 reduction scenario in 2025 and a 30 % CO2 reduction scenario in 2030 based on the 2019 baseline fleet. Most heavy-duty vehicles (HDVs) are nowadays powered by diesel engines. Diesel powertrain hybridization has demonstrated its ability to significantly reduce the fuel consumption and thus the CO2 emissions in various medium duty and heavy duty applications. This paper presents a comprehensive simulation study to evaluate the fuel savings potential of a serial-parallel hybrid heavy duty truck. The innovative configuration consists of a transmission with a reduced number of gears and parts designed to achieve a good compromise between system losses and weight. The two electric machines integrated into the dedicated hybrid transmission system enable three different driving modes, namely electric driving with one or two electric machines, serial driving and a parallel mode. The fuel economy results as well as the tailpipe pollutant emissions are compared with a conventional powertrain and a parallel hybrid (P2) configuration in different operating profiles. A future emissions legislation scenario is therefore introduced. Optimal sizing of the electrical components of the hybrid configurations (battery and electric machines) will be considered. Also, the total purely electric driving range of the electrified powertrains will be compared to current industrial benchmarks.
Implementing Analysis of Hydrogen storage tank for Fuel Cell Electric Vehicle to provide a Robust Design
Authors:   SEOYON R&D Center, REPUBLIC OF KOREA, YANG HEESEUNG , CHOI JEAJUN , KIM WONGIL
Published: April 2022

Despite the recent international climate agreements, carbon emissions are steadily increasing, and the environment is expected to get worsen due to exits from Paris climate agreement and resistance of car makers in internal combustion engines. So for those reasons, the automobile regulations by countries are being strengthened to reduce environmental pollution, and the electric vehicle market is on growing which is Eco-friendly. Current stage of electric vehicles have several technical limitations, and the biggest issue among them is mileage. To overcome such limitations, weight reduction of vehicle parts and technology innovations of battery are needed. Particularly for reducing vehicle weights, various Automotive OEMs have been making efforts in developing light weight parts made of plastics that can replace steel for instance. And, some of them are in already mass production. In this study, as a solution to this weight-reduction issue, we focused on vehicle parts weight reduction by making the tailgate ultra-lightweight. Plastic tailgates are currently being mass-produced in some OEM by using SMC (sheet molded compound) method. One of the disadvantage of using SMC method to produce plastic tailgate is that producing cost can increase. Also, parts weight reduction cannot be achieved effectively. To overcome such weaknesses, we applied the thermoplastic injection molding technique to overcome such disadvantages in making plastic tailgates. For plastic tailgate, PP (polypropylene) containing glass fiber was used to achieve light weight and finally assembled with tailgate inner & outer using adhesive. In the case of rear glass, PC (Polycarbonate) glazing technology was used to further maximize its weight reduction. Through PC glazing, weight can be reduced approximately by 35% compare to general type of glass. Also, high-harness film was applied to ensure light resistance as well as the scratch resistance. Finally, the performance of ultra-lightweight plastic tailgates that we developed were tested and verified.
Study on Driver-In-the-Loop Test of a ESC Strategy
Authors:   wuhan university of technology, CHINA, pei xiaofei , sun daoyuan ,   wuhan university of technology, CHINA, chen zhenfu ,   wuhan university of technology, CHINA, zhang xinkang ,   wuhan university of technology, CHINA
Published: April 2022

With the shorter development cycle, how to validate and calibrate Electronic Stability Control (ESC) algorithm quickly, safely and reliably is more and more important. A Driver-In-the-Loop (DIL) test method is proposed for the development of ESC control strategy and calibration of the key parameters. It’s worthwhile from two aspects, the subjective evaluation from DIL is an important supplement for ESC. On the other hand, the result of DIL test is closer to the real vehicle conditions. In this paper, a hierarchical ESC controller is presented based on the regulation of yaw-moment firstly. In the upper controller, the yaw rate control module, vehicle slip angle control module and engine control module is designed respectively to determine the desired yaw-moment based on the estimation of the vehicle steering state. Then, the additional yaw moment is coordinated by the yaw moment from the yaw rate control module and vehicle slip-angle control module in the arbitration module. While in the lower controller, the braking wheel is selected first and desired wheel longitudinal force is obtained. Then, the desired wheel slip is calculated by estimation of wheel state and achieved by wheel-slip tracking. Finally, ESC control strategy is verified and calibrated by DIL and Model-in-the-loop (MIL) based on a NI PXI platform which consists of four parts: hardware system of ESC, signal acquisition and execution system, target computer and host computer. The comparative tests are implemented respectively according to the specification of ISO 3888 DLC with high/low-mu friction road and ISO 19364 steady-state circular test with low-mu road. The test results show that ESC control strategy meets the performance requirements of vehicle handling stability, and the calibration of controller’s key parameters can be implemented quickly through subjective evaluation considering the real driver’s behavior responses. Hence, the DIL test method provides more details approaching real vehicle test.
CARACTERIZAÇÃO REOLÓGICA DE PECTINA EXTRAÍDA DE RESÍDUOS DE FRUTA PARA A COMPOSIÇÃO DE BIOTINTA PARA REGENERAÇÃO DE TECIDO TRAQUEAL
Authors: HENRIQUE FERRARESI MACKSON , AUGUSTA MIQUELUTTI GIULIA , CRISTINA DAMETTO ALESSANDRA , DA SILVA BARUD HERNANE , ALVARENGA REZENDE RODRIGO
Published: April 2022

MILHÕES DE PACIENTES LUTAM ANUALMENTE PELA VIDA RECORRENDO A TRATAMENTOS ALTERNATIVOS PARA MINIMIZAR LESÕES TRAQUEAIS E A MAIORIA NÃO OBTÉM RESULTADOS DESEJADOS, POIS, ATÉ O MOMENTO, NÃO HÁ DESCRITO NA LITERATURA TRATAMENTOS ASSERTIVOS NA CURA DESSAS INTERCORRÊNCIAS. DESTA FORMA, ESSES PACIENTES SÃO SUBMETIDOS A VÁRIAS ABORDAGENS REPETIDAMENTE O QUE ACABA LHES OCASIONANDO DANOS FÍSICOS E PSICOLÓGICOS. NESTE SENTIDO, A ENGENHARIA DE TECIDOS VEM SE DESTACANDO POR OFERECER NOVAS APLICAÇÕES MÉDICAS CORRETIVAS E/OU SUBSTITUTIVAS COM O DESENVOLVIMENTO DE ESTRUTURAS CAPAZES DE REGENERAR ÓRGÃOS E TECIDOS LESIONADOS. ESTE ARTIGO É DIRECIONADO AO ESTUDO REOLÓGICO PARA CARACTERIZAÇÃO DA PECTINA FONTE VEGETAL - DA MANGA PARA O DESENVOLVIMENTO DE UMA BIOTINTA POR (BIO) IMPRESSÃO COM O OBJETIVO DE REGENERAR O TECIDO TRAQUEAL LESIONADO.
DESENVOLVIMENTO DE GUIA CIRÚRGICO PARA CASO DE MACRODACTILIA ISOLADA DO PÉ UTILIZANDO TECNOLOGIAS TRIDIMENSIONAIS
Authors: ALBERTO MARQUES DOS SANTOS FILHO CARLOS , VINÍCIUS ARAÚJO SALES LUCAS , MORAES RODRIGUES DA COSTA JÚLIA , DINIZ GALLARDO ISABELLA , KELLSSYA LEITE FILGUEIRA ANNA , RAMOS CASTELO BRANCO RODOLFO , YASMYNE NASCIMENTO MARTINS KETINLLY
Published: April 2022

COM O PASSAR DOS ANOS AS TECNOLOGIAS TRIDIMENSIONAIS (3D) VEM SENDO CADA VEZ MAIS EMPREGADAS EM CIRURGIAS ORTOPÉDICAS, POR FACILITAR A VISUALIZAÇÃO 3D, AJUDAR NUM PLANEJAMENTO CIRÚRGICO MAIS PRECISO E POSSIBILITAR O DESENVOLVIMENTO DE MODELOS FÍSICOS COM A ANATOMIA REAL DO PACIENTE. A MACRODACTILIA É UMA ANOMALIA RARA CARACTERIZADA PELO AUMENTO DO VOLUME DOS DEDOS DA MÃO OU DO PÉ, ONDE NA MAIORIA DOS CASOS SÃO NECESSÁRIAS INTERVENÇÕES CIRÚRGICAS PARA CORREÇÃO DO MEMBRO. O SEGUINTE ESTUDO OBJETIVA O DESENVOLVIMENTO DE UMA GUIA DE CIRURGIA CUSTOMIZADA, PARA O TRATAMENTO CIRÚRGICO DE UM CASO DE MACRODACTALIA ISOLADA NA REGIÃO DO PÉ. TODO O ESTUDO FOI DESENVOLVIDO EM SETE ETAPAS METODOLÓGICAS, ONDE PRIMEIRAMENTE FORAM LEVANTADAS INFORMAÇÕES BIBLIOGRÁFICAS SOBRE O CASO, LOGO EM SEGUIDA PASSANDO PELA CAPTAÇÃO DAS IMAGENS BIDIMENSIONAIS DA ANATOMIA DO PACIENTE QUE PASSARAM POR TRATAMENTO UTILIZANDO O SOFTWARE INVESALIUS ®, COM ESSAS IMAGENS FOI POSSÍVEL REALIZAR O PLANEJAMENTO CIRÚRGICO DO CASO, OBTENDO-SE ASSIM OS BIOMODELOS DIGITAIS FIEIS A ANATOMIA DO PACIENTE, LOGO EM SEGUIDA PARTIU-SE PARA O DESENVOLVIMENTO DA GUIA DE CIRURGIA UTILIZANDO OS SOFTWARES MESHMIXER ® E AUTODESK INVENTOR ®, PARA ENFIM NA ÚLTIMA ETAPA REALIZAR A MANUFATURA DE TODOS OS MODELOS. CONSTATOU-SE QUE A APLICAÇÃO DAS TECNOLOGIAS 3D FACILITOU O PLANEJAMENTO CIRÚRGICO OTIMIZANDO E REDUZINDO TEMPO DE TODO O PROCESSO DA CIRURGIA, DEVIDO A VISUALIZAÇÃO 3D PRÉVIA E A OBTENÇÃO DOS BIOMODELOS DA ANATOMIA DO PACIENTE. JÁ NA GUIA DE CIRURGIA OBSERVOU-SE ALTO GRAU DE CUSTOMIZAÇÃO DO DISPOSITIVO, COM BAIXO CUSTO E TEMPO DE FABRICAÇÃO.
DEVELOPMENT OF NANOCAPSULES FOR THE TREATMENT OF SPINAL CORD INJURY
Authors: ZIMMERMANN RAFAELA , IGLESIAS BRAGHIROLLI DAIKELLY , PRANKE PATRICIA
Published: April 2022

INTRODUCTION: SPINAL CORD INJURY (SCI) IS A SERIOUS DISEASE YET THERE IS NO TRULY SUCCESSFUL TREATMENT. IN THIS WORK, DIFFERENT OILS HAVE BEEN USED IN THE PREPARATION OF NANOCAPSULES (NCS), TO ENCAPSULATE THE NICOTINE FOR THE TREATMENT OF SCI AND COMPARE IT IN TERMS OF DIAMETER, POLYDISPERSITY INDEX (PDI), ZETA POTENTIAL, AND ENCAPSULATION EFFICIENCY (EE). METHODOLOGY: NCS WERE PREPARED USING POLY (LACTIC-CO-GLYCOLIC ACID) (PLGA) THROUGH THE TECHNIQUE OF INTERFACIAL POLYMER DEPOSITION. IN GROUP I, GRAPE SEED OIL WAS USED, IN GROUP II CASTOR OIL, IN GROUP III COPAIBA OIL, AND IN GROUP IV A?A? OIL. THE CHARACTERIZATION OF THE NCS WAS CONDUCTED IN ZETASIZER AND THE EE BY MASS SPECTROMETRY. RESULTS: THE NCS OF GROUP I EXHIBITED AN AVERAGE DIAMETER OF 214.9 NM, PDI OF 0.351, ZETA POTENTIAL OF -47.5 MV, AND EE OF 15.88%. GROUP II PRESENTED THE AVERAGE DIAMETER OF 207.7 NM, PDI OF 0.271, AND ZETA POTENTIAL OF -27.2 MV, AND EE OF 91.27%. GROUP III EXHIBITED AN AVERAGE DIAMETER OF 190.2 NM, PDI OF 0.421, ZETA POTENTIAL OF -35.5 MV, AND EE OF 37.3%. GROUP IV PRESENTED THE AVERAGE DIAMETER OF 121.4 NM, PDI OF 0.418, ZETA POTENTIAL OF -22.3 MV, AND EE OF 32.45%. CONCLUSIONS: THESE RESULTS REVEAL THAT ALL GROUPS HAVE ADEQUATE SIZE, ZETA POTENTIAL, AND POLYDISPERSION, WHICH ATTESTS TO THEIR STABILITY, BUT GROUP II HAS EXCELLENT EE COMPARED TO THE OTHER GROUPS. THE NEXT PHASE WILL BE THE EVALUATION OF THE NC RELEASE PROFILE.
O USO DE BIOMODELOS 3D COMPARADO A MÉTODOS TRADICIONAIS NO ENSINO DE ANATOMIA PARA ESTUDANTES DE MEDICINA
Authors: MORAES RODRIGUES DA COSTA JÚLIA , DINIZ GALLARDO ISABELLA , ALBERTO MARQUES DOS SANTOS FILHO CARLOS , VINÍCIUS ARAÚJO SALES LUCAS , LEITE FILGUEIRA ANNA KELLSSYA , RAMOS CASTELO BRANCO RODOLFO , YASMYNE NASCIMENTO MARTINS KETINLLY
Published: April 2022

NOS ÚLTIMOS ANOS, OS BIOMODELOS FEITOS A PARTIR DA TECNOLOGIA DE IMPRESSÃO 3D, TAMBÉM CHAMADA DE MANUFATURA ADITIVA, TÊM SIDO INCORPORADOS À ÁREA DA SAÚDE, FACILITANDO A VISUALIZAÇÃO DE ESTRUTURAS ANATÔMICAS, SENDO ÚTIL PARA ENSINO, PLANEJAMENTO CIRÚRGICO E TOMADA DE DECISÕES CLÍNICAS E CIRÚRGICAS. O USO DESSA TECNOLOGIA NO CONTEXTO ACADÊMICO PODE SER DE GRANDE VALIA NA FORMAÇÃO DE FUTUROS PROFISSIONAIS DA SAÚDE. DIANTE DISTO, A PRESENTE REVISÃO INTEGRATIVA REÚNE ESTUDOS CLÍNICOS RANDOMIZADOS A FIM DE ESCLARECER SE O USO DE BIOMODELOS NO ENSINO DE ANATOMIA PARA ESTUDANTES DE MEDICINA É SUPERIOR COMPARADO AO USO DE MÉTODOS TRADICIONAIS DE ENSINO. A PESQUISA FOI REALIZADA EM TRÊS BASES DE DADOS, CONTANDO COM UMA ESTRATÉGIA DE BUSCA ESPECÍFICA PARA CADA BASE. FORAM ENCONTRADOS 159 ARTIGOS, MAS APENAS CINCO CORRESPONDERAM AOS CRITÉRIOS DE ELEGIBILIDADE. OS ARTIGOS SELECIONADOS COMPARARAM OS BIOMODELOS COM ATLAS 2D, PALESTRAS, MATERIAL TEXTUAL OU IMAGENS 3D COMPUTADORIZADAS. OS ESTUDANTES QUE TIVERAM ACESSO À BIOMODELOS APRESENTARAM UM DESEMPENHO MELHOR DO QUE OS ESTUDANTES QUE FORAM EXPOSTOS A OUTRO MÉTODO. PORTANTO, A PARTIR DESTA REVISÃO, O USO DE BIOMODELOS É EFICAZ E SUPERIOR COMPARADO AO USO DE MÉTODOS TRADICIONAIS NO CONTEXTO DO ENSINO DE ANATOMIA.
PENERAPAN ALGORITMA NAÏVE BAYES UNTUK PENERIMAAN PESERTA DIDIK BARU
Authors: Yusnita Amelia , Lailiyah Siti , Saumahudi Khoiri
Published: April 2022

Penerimaan peserta didik baru adalah proses pendaftaran dan penyeleksian siswa dari sekolah lama ke sekolah baru yang disertai dengan syarat-syarat yang sesuai dengan masing-masing sekolah. Setiap sekolah harus menyiapkan secara tekhnis dalam proses penerimaan peserta didik baru sehingga dapat melakukan proses penerimaan dengan lebih selektif. Metode Naïve Bayes digunakan dalam penyeleksian calon peserta didik baru dengan memprediksi nilai probabilitas yang dimasukkan berupa kriteria-kriteria yang dibutuhkan yaitu nilai hasil ujian nasional dan nilai tes dari beberapa bidang studi. Metode waterfall digunakan dalam proses pengembangan sistem, alat bantu perancangan sistem yang digunakan adalah flowchart. Hasil dari penelitian ini adalah berupa sistem pendukung keputusan untuk penerimaan peserta didik baru yang sistemnya akan melakukan proses perhitungan dari nilai kriteria dan sub kriteria menggunakan metode Naïve Bayes, dan hasil outputnya berupa laporan hasil seleksi peserta didik yang diterima dan tidak diterima. Pada tahap ini aplikasi diuji menggunakan pengujian Blackbox, hasil yang diharapkan dari pengujian ini adalah keberhasilan
SIMPLE MULTI ATTRIBUTE RATING TECHNIQUE(SMART) PADA SISTEM PENDUKUNG KEPUTUSAN UNTUK MENENTUKAN PEMILIHAN PEGAWAI BERPRESTASI PADA PUSKESMAS SEPARI III TENGGARONG SEBERANG
Authors: Nursobah Nursobah , Ekawati Hanifah , Ratmini Sri
Published: April 2022

Tujuan dari penelitian ini adalah untuk menghasilkan Sistem Pendukung Keputusan Menentukan Pemilihan Pegawai Berprestasi Dengan Metode Simple Multi Attribute Rating Technique (Smart) pada Puskesmas Separi III Tenggarong Seberang dengan harapan dapat membantu dalam pemilihan Pegawai Berprestasi. Dengan menggunakan bahasa pemrograman Visual Basic 6.0 dan databasenya menggunakan Microsoft Access. Dalam penelitian ini, teknik pengumpulan data yang digunakan adalah studi pustaka, studi lapangan, observasi dan wawancara.Sistem Pendukung Keputusan Menentukan Pemilihan Pegawai Berprestasi, merupakan sistem yang dibuat untuk membantu dalam pengambilan keputusan dalam Menentukan Pemilihan Pegawai Berprestasi pada Puskesmas Separi III Tenggarong Seberang dengan menggunakan bantuan Metode Metode Simple Multi Attribute Rating Technique (Smart).Hasil dari penelitian ini adalah dibuatnya sistem pendukung keputusan untuk Menentukan Pemilihan Pegawai Berprestasi berdasarkan hasil penilaian Pegawai. Pengguna dapat menginputkan data Pegawai, data penilaian Pegawai disetiap kriteria, kemudian sistem akan mencari solusi dengan Metode Simple Multi Attribute Rating Technique. Setelah keputusan didapatkan, maka sistem akan menampilkan keputusan tersebut.
RANCANG BANGUN KANTIN DAN PENGADUAN PELAYANAN PADA KANTIN AL-KHAIR SMP N 2 Kec. KOTA BANGUN
Authors: Hanafi Sapran , Nursobah Nursobah , Yunita Yunita
Published: April 2022

Rancang Bangun kasir dan pengaduan pelayanan pada kantin Al-Khair SMP N 2 Kec. Kota Bangun ini bertujuan untuk membuat suatu aplukasi untuk memudahkan penjual dalam melakukan transaksi dan memudahkan pendataan yang  didalamnya terdapat proses transaksi antara pembeli dan penjual, dan laporan yang bisa mempermudah pendataan. Dan memudahkan siswa dalam menyampaikan keluhannya terhadap pelayanan yang telah diberikan kantin.

Hasil penelitian ini adalah dengan adanya rancang bangun ini maka bisa dibuat aplikasi untuk petugas kantin akan lebih efisien dalam melakukan transaksi dan lebih efisien dalam melakukan pendataan makanan dan minuman yang telah dijual. Dan bagi kepala kantin juga bisa mendapatkan laporan makanan dan minuman yang telah terjual dengan lebih akurat. Dan bagi petugas kantin dan kepala kantin bisa mengetahui keluhan para siswa terhadap pelayanan kantin.
MEMBANGUN SIDE SCROLLING GAME FLYING ENGGANG BERBASIS ANDROID DENGAN GODOT ENGINE
Authors: Tobi Cladio Alessandro Ryan , Andrea Reza , Yusika Andi
Published: April 2022

Mobile game adalah sebuah game yang didesain dan dimainkan melalui mobile devices, seperti PDA, smartphone, tablet PCs, dan portable media player. Dan sekarang ini, mobile game telah dibuat di berbagai macam platform seperti Symbian, Apple IOS, Android serta Windows Phone. Game Flying Enggang adalah game yang bergenre Arcade atau Side Scrolling yang dibuat dengan menggunakan aplikasi Godot Engine yang bersifat open source dalam pembuatan game ini. Game Flying Enggang ini memiliki konsep yang bertujuan untuk menguji konsentrasi seseorang dalam menerbangkan burung Enggang sebagai karakter utama sehingga dapat meloloskan diri dari rintangan yang berupa tiang dan mendapatkan poin atau nilai sebanyak-banyaknya. Game Flying Enggang ini juga bertujuan untuk memperkenalkan beberapa bangunan icon yang ada di kota Samarinda. Dalam penelitian ini metode pengembangan sistem yang digunakan yaitu tahapan pengembangan multimedia dan berbasis android. Kesimpulan dari penelitian ini berupa game flying enggang berbasis android yang menggunakan Godot Engine yang dapat memperkenalkan beberapa icon bangunan di kota Samarinda serta burung Enggang sebagai hewan khas Kalimantan Timur.
Rac1 Rich Proline are OPA1 Flux Influencer for PLCs and IFNs Synthesis where Immune and Toxicity Due Deficiency in Synthetase and in Proline Synthesis
Authors:   Biomedical and Molecular Studies Canada, Toronto, Goldwin Ave and Cairo Egypt, El Tantawi Ashraf Marzouk
Published: April 2022

Rac1 is basis for ATPase, ribosomes repairs, Gactin activities, and regulating fatty Acyl-COA productions (upon OPA1 function) which are main for epidermal growth factor “EGF” synthesis and for both PLCs and IFNs synthesis. Rac1 basically are S6K rich Proline and hydrophobic amino acids that each amino acid especially Proline characterize Rac1 for scpsific functions and activity for regulating specific anti-inflammatory cycles and specific anti-inflammatory growth, that Rac1 has the roles of acting on inflammatory sources for analyzing and producing long fatty chains which will follow the OPA1 oxidative function (which activated by GTPase which promoted by Rac1 active molecules ) for producing fatty Acyl-COAs isoforms which considered as GP-GTP isoforms Gp-GTP gamma, GP-GTP beta, and GP-GTP alpha isoforms where some said that GTPase has been analyzed to give Gp isoforms but GTPase has activated OPA1 enzymes which produced Gp-GTP nuclear isoforms upon effect on long fatty chains, that GP-GTP beta and alpha have the roles of promoting PLCs and IFNs isoforms for anti-inflammatory processes and for anti-inflammatory growth . That The Rho family Rac1-GTPase (Gp isoforms) mediates a variety of signal transduction processes leading to activation of NADPH oxidase, actin cytoskeleton reorganization and anti-inflammatory growth.
EXERGY ANALYSIS OF GRAPHENE-BASED NANOFLUIDS IN A COMPACT HEAT EXCHANGER
Authors: KILINÇ Ferhat , UYGUN Cihan Zeki
Published: April 2022

In this study, the exergy analysis of graphene-based nanofluids in a compact heat exchanger is examined. In experiments using distilled water as the base fluid, graphene nano-ribbon and graphene oxide nanofluids were used at 0.01% and 0.02% of the volume concentrations. The experiments were carried out at 36, 40, and 44 oC fluid inlet temperatures and 0.6, 0.7, 0.8, and 0.9 m3/h mass flow rates. As a result of the calculations made for all temperature and flow rates, it was found that the exergy efficiency values of 0.01% by volume GO nanofluid were higher than the exergy efficiency of the other nanofluids used. Also, the exergy destruction values calculated for %0.01 GO were lower than the value of exergy destruction calculated for other nanofluids. It was concluded that the exergy efficiencies of nanofluids increased with the increase of the fluid flow rates and the inlet temperature of the heat exchanger. When the exergy efficiencies were compared according to the nanofluid concentrations, it was found that the exergy efficiencies decreased with the increase of the fluid concentration. It was examined that the exergy destruction values also increases with the increase of nanofluid flow rates, as well as exergy efficiency. When the exergy destructions were compared to the nanofluid concentrations, it was concluded that the exergy destructions increased with the increase of the nanofluid concentration. It was determined that the amount of increase in exergy destruction of GO nanofluid was higher than that of GNR.
SÍNDROME HEMOLÍTICO-URÊMICA NA PEDIATRIA E SUAS COMPLICAÇÕES: ANÁLISE DE CASOS
Authors: Soares Gomes Barros Fonseca Gustavo , Lima Assunção Izabely , Brandão de Sá Costa Ana Valéria , Clery da Rocha Nogueira Rebeca , Da Rocha Nogueira Arthur , Menezes de Carvalho Camilla , Pacheco Florentino João Víctor , Serrão Mendes Filho Kleber de Jesus , Cunha Mendes Neto Pedro , Barros Dias Lorena , Neves Ezon Ferraz Gabriel , Reis Santos Ana Luiza , Dos Santos Matos Amanda Caroline , Murta Filho Tarcízio Santos , Pinho de Carvalho Pascal Ana Victória
Published: April 2022

A Síndrome Hemolítico-Urêmica (SHU) é uma doença grave, caracterizada pela tríade clássica de anemia hemolítica microangiopática, trombocitopenia e insuficiência renal aguda. Esta pesquisa trata-se de uma revisão bibliográfica sistemática, de natureza quantitativa, que utilizou as plataformas PubMed, Scientific Eletronic Library On-line (SciELO) e Google Scholar como base de dados para pesquisa dos artigos científicos. A escolha dos artigos a serem utilizados nesta revisão foi realizada por meio da leitura do título, resumo e, por fim, da leitura do artigo na íntegra, sendo realizada uma análise criteriosa dos artigos fundamentados nos critérios de inclusão e exclusão supracitados. A patogênese da SHU corresponde a uma microangiopatia trombótica, apresentando um prognóstico ruim, sendo o diagnóstico realizado geralmente a partir de exclusão de outras doenças. Na primeira manifestação clínica da doença, quase metade dos pacientes evoluem ao óbito ou progridem para doença renal crônica terminal. O tratamento possui a utilização do fármaco Eculizumab, o qual apresenta um alto custo, porém a aumenta a expectativa e a qualidade de vida desses pacientes. Com isso, mais estudos acerca desta doença são necessários para o desenvolvimento de novas medidas de diagnóstico e terapias.
Strategi Promosi dan Peningkatan Omset Penjualan Pada Umkm Kain Tenun Khas Wabula Kabupaten Buton
Authors: Ridzal Nining Asniar , Sujana I Wayan , Malik Ernawati , Mahmud Mudasir Ali , Elfianti Wa Ode
Published: April 2022

Economic actors in Wabula Village, Buton Regency are actively developing the Wabula woven fabric business, but their activities are constrained by several things, namely related to advertising, production is still limited, conventional sales, no bookkeeping of businesses, lack of participation of the younger generation. These business actors lack the skills to promote their business which should be converted into sales. These problems became the basis for Community Service (PKM) activities. The method of implementing this activity is by analyzing the situation, coordinating, identifying the solution to partner problems, followed by seminars and training. So far, the promotion system carried out is still traditional promotion and seems passive, meaning that it waits for buyers to come. Awareness of using the internet for product promotion is still very low. This is because the craftsmen are parents who are technologically stuttering. For this reason, it is necessary to involve the younger generation who are technology literate. Until now, the focus of woven fabric craftsmen is still on the production and distribution process, so promotion is not a priority for business activities. As a result, the turnover obtained is not optimal. Regarding income, the craftsmen cannot mention because there is no detailed bookkeeping, nor is there a target. The lack of market share owned. This is due to the low promotion carried out and the marketing strategy is still conventional. For example, craftsmen only rely on production according to the number of orders, do not yet have ideas to add partners outside Wabula Village or use internet technology to sell.
Penguatan Pemahaman Siswa Kelas Xii Melalui Pelatihan Akuntansi
Authors: Merdekawati Eka , Pratiwi Ratih , Hidayati Aulia
Published: April 2022

SMA Negeri 6 Bogor is a senior high school in the city of Bogor. The majors at SMA Negeri 6 are science and social studies, one of the problems faced during online schools is regarding the understanding and ability of class XII students, especially social studies majors in accounting subjects, so there are concerns by the teacher that it will have an impact on students' final grades. The Accounting Study Program of college of Vocational Studies of IPB which consists of lecturers and students conducts accounting training for class XII students majoring in accounting with basic accounting materials and is proficient in preparing financial reports. This activity lasted for 1 day with 67 participants. The method applied in this community service activity is a descriptive analysis method with lectures and accounting practices from journal recording to the preparation of financial reports. The purpose of this community service activity is to strengthen understanding of accounting and proficient in preparing financial reports for students of SMAN 6 Bogor. Based on the post test results, it is known that 85% of students at SMAN 6 Bogor majoring in accounting are able to improve their understanding of accounting and prepare financial reports correctly, besides that students become motivated to study accounting and are optimistic that they will get good grades on the exam later.
Pelatihan Penyusunan Profil Usaha dan Proposal Pembiayaan Bagi Umkm
Authors: Gustriani Gustriani , Imelda Imelda , Harunurrasyid Harunurrasyid , Subardin Muhammad , Teguh Muhammad
Published: April 2022

Lack of capital is a major problem faced by business, especially micro small medium enterprises (MSME) segment. One of the ways to get capital is applying loan to financial institutions, mainly the banking industry. However, in the credit application process due to lack of information, most small and micro businesses have difficulties in preparing business proposals that are in accordance with banking standards. Therefore, the Service Team and the Economics and Business Application Laboratory of the Economics Faculty carry out community service activities. It performed with models and methods of mentoring and empowerment for micro and small businesses regarding writing business profiles and proposals for credit applications. There are at least 34 entrepreneurs in Ilir Barat II Sub-district South Sumatera Province who participated in this activity and were assisted in making company profiles as well as business proposals. The evaluation results showed an increase in understanding of how to make business profiles and proposals by 80.06 percent of participants.
Rancangan Audit 5R Untuk Mengoptimalkan Preventive Maintenance
Authors: Apriliani Fany
Published: April 2022

Education is a learning process that actively guides students to develop their self-potential and has a noble character. Islamic boarding schools also have an important role and function in education, da'wah, and community empowerment. As national education providers, they need to facilitate dormitories that meet the following aspects: capacity, comfort, cleanliness, health, and security. The problems are: the community often perceives the Islamic boarding school’s environment as poorly maintained, and the students often have various health complaints. This view needs to be proven by direct observation. Good housekeeping activities need to be evaluated regularly. This study aims to design the 5R auditas a guide for evaluating good housekeeping practices to succeedin the preventive maintenance pillar. The study object is one of the Islamic boarding schools in Bogor. The methods are 5R culture training, questionnaires, observation, and designing 5R audits. The results show that students’ understanding of 5R cultural concepts and practices increased by 30,1%. The student’s average value for good housekeeping habits reached 89,5%. However, the 5R audit has not been carried out routinely. The urgency of the 5R audit design consists of 5R activity stages, 5R audit check sheet, 5R kaizen sheet, and 5R competition.
HIPERTENSÃO MASCARADA: QUAL A IMPORTÂNCIA DA MRPA NESTE CONTEXTO?
Authors:   Hospital Esperança Recife, PE, Brasil, M Alves Marco A , de Souza Spinelli Antônio Carlos ,   Cardiocentro, Natal, RN, Brasil., D M Feitosa Audes ,   Serviço de Hipertensão do PROCAPE, Universidade de Pernambuco, Recife/PE e Instituto UNICAP de Pesquisa Cínica, Universidade Católica de Pernambuco, Recife, PE, Brasil., Nadruz Wilson ,   Unicamp, Campinas, SP, Brasil
Published: April 2022

A hipertensão arterial (HA) é o principal fator contributivo para as doenças cardiovasculares, as quais constituem a mais importante causa de morte prevenível no mundo. A falta de conhecimento da população acerca da doença, e consequentemente de um diagnóstico adequado, torna baixo o número de pessoas que se tratam. O aspecto silencioso da HA, e a má adesão ao tratamento proposto, dentre outros fatores, contribuem para o elevado risco de complicações. A medida da pressão arterial (PA) neste contexto apresenta grande importância não apenas no diagnóstico, mas também no acompanhamento de portadores de HA, podendo ser realizada de forma casual, em consultório, ou fora do mesmo com a utilização de outros métodos para tal. Dentre as medidas de PA, a monitorização residencial da PA (MRPA) se destaca. É um método destinado a fazer registro da PA fora do ambiente de consultório, obedecendo a um protocolo previamente estabelecido e normatizado. Além disto, a MRPA apresenta custos menores do que a monitorização ambulatorial da PA (MAPA). De acordo com a atual Diretriz Brasileira de HA, são considerados anormais valores de PA consultório ≥ 140/90 mmHg e de MRPA ≥ 130/80 mmHg. Sob esta perspectiva, a MRPA é um exame que permite que se faça o diagnóstico de HA verdadeira (PA elevada no consultório e na MRPA), normotensão verdadeira (PA normal no consultório e na MRPA), HA do avental branco (HAB) (PA elevada no consultório e normal na MRPA) e HA mascarada (HM) (PA normal no consultório e elevada na MRPA). O diagnóstico de HM é bastante relevante na prática clínica, pois em termos prognósticos, a HM apresenta um risco cardiovascular maior que a HAB e a normotensão verdadeira. Além disto, a incidência de eventos cardiovasculares na HM é similar ou até superior à da HA verdadeira.