bluuebunny/crossref_metadata_2025 huggingface dataset:
Prognostic Implications of Left Ventricular Global Longitudinal Strain in Patients With Surgically Treated Mitral Valve Disease and Preserved Ejection Fraction
Authors: Lee Seon Hwa , Lhagvasuren Purevjargal , Seo Jiwon , Cho Iksung , Kim Dae-Young , Hong Geu-Ru , Ha Jong-Won , Shim Chi Young
Published: January 2022

Background

This study investigated whether left ventricular (LV) global longitudinal strain (LV-GLS), as an LV function parameter less affected by mitral valve (MV) repair or prosthesis, is associated with clinical outcomes in patients with surgically treated MV disease.

Methods

Among 750 patients who underwent MV surgery, we assessed LV-GLS by speckle tracking echocardiography in 344 patients (148 men, mean age 58 ± 13 years) who showed preserved LV ejection fraction on echocardiography between 6 months and 2 years after MV surgery and who did not undergo aortic valve surgery. The assessed clinical events included admission for worsening of heart failure and cardiac death.

Results

During a period of 42.4 ± 26.0 months, 32 (9.3%) patients were hospitalized for worsening heart failure, and 3 (0.8%) died due to cardiac causes. The absolute value of LV-GLS (|LV-GLS|) was significantly lower in patients with clinical events than in those without (12.1 ± 3.1 vs. 15.0 ± 3.2%, p < 0.001) despite comparable LV ejection fraction between groups. |LV-GLS| showed predictive value for clinical events (cut-off 13.9%, area under the curve 0.744, p < 0.001). Patients with |LV-GLS| ≤14.0% had poorer outcomes than those with |LV-GLS| >14.0% (log-rank p < 0.001). Prognosis was worse in patients with |LV-GLS| ≤14.0% and pulmonary hypertension than among those who with |LV-GLS| ≤14.0% without pulmonary hypertension (log rank p < 0.001). In nested Cox proportional hazard regression models, reduced |LV-GLS| was independently associated with the occurrence of clinical events.

Conclusions

In patients with surgically treated MV and preserved LV ejection fraction, assessment of LV-GLS provides functional information associated with cardiovascular outcomes.
Charniodiscus and Arborea Are Separate Genera Within the Arboreomorpha: Using the Holotype of C. concentricus to Resolve a Taphonomic/Taxonomic Tangle
Authors: Pérez-Pinedo Daniel , McKean Christopher , Taylor Rod , Nicholls Robert , McIlroy Duncan
Published: January 2022

Charniodiscus is one of the most iconic and first described of the Ediacaran frondose taxa. Since the diagnosis of the holotype of C. concentricus in 1958, the scarcity and poor preservation of unequivocal specimens has resulted in genus-level taxonomic uncertainty. Since the recent reinterpretation of C. concentricus as a multifoliate frond, other Charniodiscus species—all of which are bifoliate—have been left in taxonomic limbo, with most authors comparing them to the clade Arboreomorpha and also the Rangeomorpha. Reconsideration of the taphonomy of the holotype of C. concentricus has revealed that the frond is bifoliate as first described, and also that the frondose portion was broadly conical rather than planar as previously inferred. The conical frond of Charniodiscus is thus morphologically quite different from all other frondose taxa within the Arboreomorpha. Our emendation of the generic diagnosis of Charniodiscus to encompass bifoliate arboreomorphs with conical fronds without a backing sheet distinguishes Charniodiscus concentricus and C. procerus from more planar leaf-like arboreomorphs such as Arborea arborea, A. longa and A. spinosa, all of which have a distinctive backing sheet. Additionally, we find no evidence of rangeomorph-type fractal branching in Charniodiscus.
Geological Characteristics of Deep Shale Gas in the Silurian Longmaxi Formation in the Southern Sichuan Basin, China
Authors: He Shun , Qin Qirong , Li Hu , Zhao Shengxian
Published: January 2022

To investigate the geological characteristics and exploration potential of shale gas in the southern Sichuan Basin, we analyze the coupling relationship between the hydrocarbon generation and storage conditions of the Longmaxi Formation and discuss the preservation conditions from the lateral and vertical migration mechanisms of shale gas. According to the results, the organic-rich shale at the bottom was formed in a strongly euxinic and anoxic reducing environment, the oxygen content increased in the upper water body in which the Longmaxi Formation was deposited, and the water body became oxidized. The organic matter type in the shale is dominantly type I kerogen and a small amount of type II1 kerogen. The organic matter content is more than 3.0% and is in the high-to postmature stage. The enrichment of siliceous organisms increases the organic matter and enhances the brittleness of shale, resulting in “superior hydrocarbons and a favorable reservoir”. Pyrolysis of organic matter promotes the formation of organic matter pores and dissolution pores, resulting in a coupled “source-reservoir” accumulation control system. The high vertical formation pressure guarantees the sealing of shale and restrains the lateral escape of shale gas. The high-angle intersection of the highly filled fractures and the current crustal stress can effectively enhance the fracture sealing and inhibit the vertical escape of shale gas, forming a three-dimensional effective closure. Hence, the area featuring a short tectonic uplift time, small amplitudes, large-scale underdeveloped fractures, and a high formation pressure coefficient is a favorable area for shale gas exploration, according to the analysis of three-dimensional preservation conditions.
Oilseed Cover Crops for Sustainable Aviation Fuels Production and Reduction in Greenhouse Gas Emissions Through Land Use Savings
Authors: Taheripour Farzad , Sajedinia Ehsanreza , Karami Omid
Published: January 2022

Induced Land Use Changes (ILUCs) can decrease the environmental benefits of Sustainable Aviation Fuels (SAFs) if produced from traditional food crops. The development of oilseed cover crops can eliminate the side effect of ILUCs for biofuel production because they come in rotation with the major crops with some savings in demand for new cropland. This study implemented Life Cycle Analysis (LCA) and GTAP-BIO to estimate ILUC emissions values, the potentially available area, and total possible emissions savings of producing SAFs from carinata, camelina, and pennycress in the United States. The results suggest that: 1) the meals produced in conjunction with increases in Sustainable Aviation Fuel production from carinata, camelina, and pennycress could reduce land use emissions by 12.9, 15.3, and 18.3 gCO2e/MJ, respectively; 2) the total area of available land for producing these feedstocks could be about 29.3 million ha in 2035; and 3) using this area of land for SAF production, depends on the mix of oilseed cover crops that can be produced in practice, could generate up to 92 million metric tons of savings in GHG emissions per year. The projected emissions savings is about 11% of the current global GHG emissions generated by the aviation industry. Providing incentives to encourage farmers to produce these cover crops and facilitating investment in producing SAF from these cover crops are the most important factors that could help the aviation industry to enhance emissions savings.
Thermal Management of a 48 V Lithium-Ion Battery Pack by Semiconductor Refrigeration
Authors: Yang Rui , Li Kuining , Xie Yi , Li Wei , Qian Yuping , Zhang Yangjun , Zhang Hongxiang
Published: January 2022

At present, 48 V mild hybrid battery systems are widely used in hybrid electric vehicles to reduce fuel consumption and emissions. The battery pack often operates at high discharge/charge rates and requires an efficient and compact battery thermal management system (BTMS) to control its temperature, improve its electrical performance and extend its life. Due to their short start-up times and simple structures, semiconductors can provide rapid refrigeration and cool a battery quickly in response to sudden high current rates. Therefore, semiconductors were applied to the BTMS of a 48 V battery. The performance of the semiconductor-based BTMS was studied by simulation and experiment at high discharge rates (up to 9.375 C). Firstly, a thermal model of the BTMS was developed that integrates a resistance-based battery thermal model, a semiconductor thermal model and a three-dimensional fluid-solid coupled heat transfer model. Unlike a traditional thermal model, the proposed model considers the joint influences of SOC, temperature and current on battery resistance and improves the predictive precision of the battery’s thermal behaviour. The thermal model was verified by an experiment, with the results showing that it could precisely describe the temperature increase in the battery (maximum average absolute error within 0.9°C). Finally, the BTMS thermal model was applied to predict the cooling performance of the semiconductor BTMS at an ambient temperature of 37°C and high current rates (up to 9.375 C), which was compared with that of an air-cooled BTMS. The results demonstrate that the semiconductor-based BTMS achieves lower battery temperature than the air-cooled BTMS and ensures a temperature difference within the 48 V pack of <1.6°C.
Operation State Evaluation Method of Smart Distribution Network Based on Free Probability Theory
Authors: Zhang Jiaxin , Wang Bo , Wang Hongxia , Ma Hengrui , Ma Fuqi , Li Yifan , Zhang Yingchen
Published: January 2022

In view of the current situation that the new generation of smart grids with “double high” characteristics is in urgent need of effective state evaluation methods due to the characteristics of strong volatility and diverse demands, a method of operation state evaluation of smart distribution networks based on free probability theory is proposed, which is combined with high-order moment indexes to describe the operation trajectory of distribution networks from a data-driven perspective. First, the state assessment problem of smart distribution networks is modeled as a binary hypothesis testing problem, and the asymptotic free equation is established based on free probability theory to provide a framework for state assessment of distribution networks. Then, a high-order moment evaluation index is proposed, combined with the sliding time window processing, and the high-order moment sequence was obtained based on the high-dimensional data of the distribution network, which is used to describe the state evolution of the distribution network. Finally, this method is applied to a certain 110-kV distribution network. The analysis of an example shows that the proposed evaluation framework and indicators can effectively reflect the data changes in the distribution network and support the state assessment and evolution analysis of the distribution network.
Facilitating Uptake of Post-abortion Contraception for Young People in Kenya
Authors: Mbehero Faith , Momanyi Ruth , Hesel Kate
Published: January 2022

Globally, maternal mortality is unacceptably high, and unsafe abortion is the most easily preventable cause of maternal death. Post-abortion contraception, recognized as a High Impact Practice in Family Planning, can reduce rates of unintended pregnancies and unsafe abortion and ultimately save lives. Implementation of this, however, is limited, especially for young people. This case study documents strategies, results, and lessons learned from Planned Parenthood Global's project in South West Kenya, which improved access to and provision of comprehensive abortion care, including safe abortion, post-abortion care and post-abortion contraception, at 80 public and private health facilities. By prioritizing training and mentorship of mid-level providers on both medical and surgical abortion care, post-abortion contraception and youth friendly services, in addition to community engagement and referrals, this intervention removes common barriers to care for women and young people. Eighty-five percent of abortion care clients served by the project accepted same-day contraception, with the vast majority—including 90% of clients aged 24 and under—choosing long-acting reversible contraception. The Closing the Gap project was funded by an anonymous donor.
Simulating the Cortical Microcircuit Significantly Faster Than Real Time on the IBM INC-3000 Neural Supercomputer
Authors: Heittmann Arne , Psychou Georgia , Trensch Guido , Cox Charles E. , Wilcke Winfried W. , Diesmann Markus , Noll Tobias G.
Published: January 2022

This article employs the new IBM INC-3000 prototype FPGA-based neural supercomputer to implement a widely used model of the cortical microcircuit. With approximately 80,000 neurons and 300 Million synapses this model has become a benchmark network for comparing simulation architectures with regard to performance. To the best of our knowledge, the achieved speed-up factor is 2.4 times larger than the highest speed-up factor reported in the literature and four times larger than biological real time demonstrating the potential of FPGA systems for neural modeling. The work was performed at Jülich Research Centre in Germany and the INC-3000 was built at the IBM Almaden Research Center in San Jose, CA, United States. For the simulation of the microcircuit only the programmable logic part of the FPGA nodes are used. All arithmetic is implemented with single-floating point precision. The original microcircuit network with linear LIF neurons and current-based exponential-decay-, alpha-function- as well as beta-function-shaped synapses was simulated using exact exponential integration as ODE solver method. In order to demonstrate the flexibility of the approach, additionally networks with non-linear neuron models (AdEx, Izhikevich) and conductance-based synapses were simulated, applying Runge–Kutta and Parker–Sochacki solver methods. In all cases, the simulation-time speed-up factor did not decrease by more than a very few percent. It finally turns out that the speed-up factor is essentially limited by the latency of the INC-3000 communication system.
Prognostic Significance of Modified Advanced Lung Cancer Inflammation Index in Patients With Renal Cell Carcinoma Undergoing Laparoscopic Nephrectomy: A Multi-Institutional, Propensity Score Matching Cohort Study
Authors: Mao Weipu , Wang Keyi , Wu Yuan , Ni Jinliang , Zhang Houliang , Wang Yidi , Wu Zonglin , Liu Ruiji , Geng Jiang , Chen Shuqiu , Chen Ming
Published: January 2022

Background

We conducted a multi-institutional clinical study to assess the prognostic value of the advanced lung cancer inflammatory index (ALI) and modified ALI (mALI) in patients with renal cell carcinoma (RCC).

Methods

We collected 440 patients who underwent laparoscopic nephrectomy at three centers from 2014 to 2019. ALI was defined as body mass index (BMI) × serum albumin (ALB)/neutrophil-to-lymphocyte ratio (NLR) and mALI as L3 muscle index × ALB/NLR. Kaplan-Meier curves, receiver operating characteristic (ROC) curves and Cox survival analysis were used to assess the effect of ALI and mALI on overall survival (OS). In addition, we performed 1:1 propensity score matching (PSM) for the high mALI and low mALI groups to further explore the impact of mALI on survival in RCC patients.

Results

The optimal cut-off values for ALI and mALI were 40.6 and 83.0, respectively. Based on the cut-off values, we divided the patients into high ALI and low ALI groups, high mALI and low mALI groups. ALI and mALI were significantly associated with the AJCC stage, Fuhrman grade, T stage, and M stage. Low ALI (p = 0.002) or low mALI (p < 0.001) was associated with poorer prognosis. ROC curves showed that mALI was a better predictor of OS than ALI. Multivariate Cox regression analysis showed that low mALI (aHR = 2.22; 95% CI 1.19–4.13, p = 0.012) was an independent risk factor for OS in RCC patients who underwent nephrectomy, while ALI (aHR = 1.40; 95% CI 0.73–2.66, p = 0.309) was not significantly associated. Furthermore, after PSM analysis, we found that mALI remained an independent risk factor for OS (aHR = 2.88; 95% CI 1.33–6.26, p = 0.007) in patients with RCC.

Conclusions

For RCC patients undergoing laparoscopic nephrectomy, low ALI and low mALI were associated with poor prognosis, and preoperative mALI can be used as a potential independent prognostic indicator for RCC patients.
Oxysterol-Binding Protein 2 Promotes Pancreatic Ductal Adenocarcinoma Progression Through Epithelial-Mesenchymal Transition
Authors: Huang Shuai , Zhang Xudong , Luo Kai , Jiang Li , Jiang Jianhua , Li Renfeng
Published: January 2022

Oxysterol-binding protein 2 (OSBP2) is crucial for promoting the growth and development of cancers; however, its effects on pancreatic ductal adenocarcinoma (PDAC) are still unclear. Here, we report that OSBP2 is an efficient tumor-associated protein to lead to extremely malignant characteristics in PDAC. We discovered that increased OSBP2 expression in primary tumors was associated with shorter survival in PDAC patients. Therefore, we used immunohistochemistry (IHC) to analyze the levels of OSBP2 expression in PDAC tissues and adjacent paracancerous tissues. We used wound healing and Transwell assays to evaluate the effects of OSBP2 on PDAC cell (ASPC-1 and BXPC-3) migration and invasion, respectively, and CCK-8 and Annexin V/PI double staining to evaluate the effects of OSBP2 on PDAC cell proliferation and apoptosis, respectively. Western blotting was used to analyze the effect of OSBP2 on the PDAC cell phenotype. We also explored the effect of OSBP2 on chemosensitivity to gemcitabine (GEM) and 5-fluorouracil (5-FU). We validated these findings in an in vivo mouse model. The data show that OSBP2 overexpression promoted PDAC cell migration, invasion, proliferation and chemotherapy resistance, and decreased apoptosis. OSBP2 overexpression downregulated E-cadherin expression and upregulated N-cadherin, vimentin, Snail, Slug, ZEB1, and β-catenin expression. Taken together, our findings indicated that OSBP2 was overexpressed in PDAC and that upregulation of OSBP2 may promote PDAC progression. Therefore, OSBP2 may have potential diagnostic and therapeutic value in PDAC.
PAQR5 Expression Is Suppressed by TGFβ1 and Associated With a Poor Survival Outcome in Renal Clear Cell Carcinoma
Authors: Tao Chang , Liu Wang , Yan Xiang , Yang Min , Yao Si , Shu Qiang , Li Benyi , Zhu Runzhi
Published: January 2022

Background

Renal cell carcinoma (RCC) was sex-hormone responsive, and clinical trials using progesterone significantly reduced the incidence of distal metastasis after radical nephrectomy. Recently membrane-bound progesterone receptors (mPRs) were discovered to mediate the non-genomic effect of progesterone. Aberrant expressions of these mPRs were reported in human breast, ovarian, urinary bladder, brain, uterine, and prostate cancers. However, their expression profiles in RCC are yet to be assessed.

Methods

Multiple datasets from RNA sequencing (RNA-seq), cDNA microarray, and proteomic analysis were used to compare gene expression between cancerous and normal kidney tissues. Immunohistochemistry was conducted to examine protein expression in kidney tissues. Promoter methylation levels were assessed for correlation analysis with gene expression.

Results

Of the seven membrane-bound progesterone receptor genes, the progestin and adipoQ receptor-5 (PAQR5) gene is predominantly expressed in normal kidney tissue but was significantly downregulated in RCC tissues. PAQR5 downregulation correlated with tumor stage, cancer grade, lymph node invasion, and distal metastasis only in clear cell RCC (ccRCC) tissues. PAQR5 downregulation was associated with an increased promoter DNA methylation and a poor survival outcome in ccRCC patients. In addition, PAQR5 expression inversely correlated with transforming growth factor beta-1 (TGFB1) expression, and TGFβ1 treatment significantly reduced PAQR5 gene expression.

Conclusion

PAQR5 is a novel prognostic biomarker in ccRCC and is negatively regulated by the TGFβ1 pathway.
Supervisor’s Negative Mood and Healthcare Workers’ Voice Behavior: A Moderated Mediation Model
Authors: Yuan Ping , Cheng Yuan , Liu Yanbin , Liu Shifeng
Published: January 2022

Healthcare workers’ voice is of importance in decreasing medical accidents and improving the efficacy of hospital units. To investigate the impact and the underlying mechanisms of supervisors’ negative mood on healthcare workers’ voice behavior, based on the mood contagion perspective, we designed a cross-sectional study, with 299 healthcare workers from mainland China completed the questionnaires. The results indicated supervisors’ negative mood was positively related to healthcare workers’ negative mood, which further led to less constructive voice and more defensive voice. Moreover, the healthcare worker’s emotional intelligence aspect of self-emotion appraisal moderated this relationship, but not others-emotion appraisal. We believe healthcare workers’ supervisors should pay attention to their negative mood expression and regulation. In the hope of reducing being influenced by supervisors’ negative mood, training about noticing and recognizing their own emotions are needed for healthcare workers.
Addressing Inequalities Toward Inclusive Governance for Achieving One Health: A Rapid Review
Authors: Eliakimu Eliudi S. , Mans Linda
Published: January 2022

Sustainable development goals (SDGs) adopted in 2015 are geared toward sustainable development through various pathways, one being reducing inequality as covered in SDG 10. Inequalities are a threat to health and wellbeing of populations and a planet Earth in which we live. This rapid review aims to identify key issues that are likely to exacerbate inequalities around the six SDGs directly related to One Health, which are SDG 3, 6, 11, 13, 14 and 15, and suggest some actions that may help to address them using inclusive governance taking into account the coronavirus disease of 2019 (COVID-19) pandemic. Informed by the literature on SDGs and using the “inclusive development concept” by Gupta and Vegelin, literature search was done in Google Scholar, PubMed Central, as well as, searching of references in the relevant articles identified using search terms from the six SDGs that are directly related to One Health. In the context of the SDGs, in order to achieve One Health through inclusive governance, and tackle inequalities, the following needs to be considered and addressed: increasing number of armed conflicts; ongoing COVID-19 pandemic; ensuring availability of water and sanitation facilities; improving city and urban areas planning to cope with climate change; improving governance arrangements for addressing climate change factoring gender and human rights; multisectoral planning for conservation of oceans, seas, and marine resources; balancing trade regulation of wildlife trade with conservation efforts; need for a research collaborative involving experts from environmental sciences, wildlife, agriculture and human health to study and develop scientific evidence on contribution of changes in land use practices to occurrence of zoonotic diseases; and need of a legislation for promoting animal welfare to protect public health. Also, inclusion of people with disabilities in the use of digital technologies is critical.
Belonging to Socially Excluded Groups as a Predictor of Vaccine Hesitancy and Rejection
Authors: Eshel Yohanan , Kimhi Shaul , Marciano Hadas , Adini Bruria
Published: January 2022

The scientific call for vaccination against the COVID-19 pandemic has met hesitancy, postponement, and direct opposition of parts of the public in several countries. Mistrusting the COVID-19 vaccine, distrusting the authorities, and unrealistic optimism, are three major reasons employed in justifying vaccine hesitancy. The present study examines two major issues. First, it strives to identify individuals that are unwilling to adhere to the vaccination process, more strongly question the effectiveness and necessity of the COVID-19 vaccine, and wonder about potential covert reasons for its administration. Second, it investigates associations between such “conspiracy” claims and the actual rejection of the vaccine. We assume that individuals belonging to social groups which are partly excluded by the general society will be less willing to fulfill the demands of this society, more inclined to reject the vaccine and associate it with some hidden conspiracy. A relatively large sample of the Israeli public (N = 2002) has responded to an anonymous questionnaire pertaining, among other things, to vaccine hesitancy and the individual level of vaccine uptake. Previous research has mainly examined the reasons for vaccine hesitancy. The present study's results indicate that three out of four social exclusion criteria (young adulthood, low level of income, and orthodox religiosity) have negatively predicted vaccine uptake and positively predicted three types of reasoning for vaccine hesitancy. Young adulthood was the strongest predictor of vaccine rejection. Attempts at convincing hesitating individuals to uptake this vaccine have often failed in many countries. As varied reasons underlie vaccine refusal, it is suggested that the approach to different vaccine rejecting groups should not be generic but rather tailor-made, in an attempt to influence their perceptions and behavior.
Assessment of Regional Spatiotemporal Variations in Drought from the Perspective of Soil Moisture in Guangxi, China
Authors: Wu Weixiong , Li Ronghui , Shao Jinhua
Published: January 2022

Understanding the changes in regional droughts is important for promoting overall sustainable development. However, the spatiotemporal dynamics of soil droughts in Guangxi under the background of global warming and regional vegetation restoration have not been studied extensively, and the potential causes are scarcely understood. Here, using TerraClimate soil moisture data, we constructed a monthly standardized soil moisture index (SSMI), analyzed the seasonal and annual spatiotemporal distribution of droughts from the perspective of soil moisture, and studied past soil drought events in Guangxi. Migration methods of drought centroid, trend analysis, and principal component decomposition were used. In the interannual dynamics, the overall SSMI increased, indicating that the soil drought situation was gradually alleviated in Guangxi. Further, the frequency of extreme and severe droughts decreased with time, mainly in autumn and winter. During early drought stages, the migration path was short, which extended as the droughts progressed. Ocean temperature and soil moisture were strongly correlated, indicating that abnormal ocean surface temperature may drive soil moisture. This study provides scientific guidance for the early warning, prevention, and mitigation of losses associated with soil droughts in Guangxi and serves as valuable reference for understanding the impacts of large-scale climate anomalies on soil moisture.
Presbeutikoi and Enteuktikoi Logoi in Hellenistic Interstate Relations. Some Further Thoughts from an Epigraphical Perspective (c. 306-205 B.C.)
Authors: Amendola Davide
Published: January 2022

L’importance croissante des interactions diplomatiques dans le monde hellénistique a conduit certains historiens et rhétoriciens à développer et à manipuler la tripartition aristotélicienne des genera dicendi afin d’y inclure les discours des ambassadeurs. S’appuyant principalement sur la documentation épigraphique, qui, malgré son importance pour la reconstruction de l’évolution de la diplomatie grecque ancienne, a été largement négligée jusqu’à présent, cet article a pour but de contribuer à la définition des caractéristiques distinctives de la rhétorique diplomatique au IIIe siècle av. J.-C. en examinant des inscriptions qui préservent les résumés ou des commentaires des présentations orales des ambassadeurs devant leur public.
I.Sicily, Open Scholarship, and the Epigraphic Landscape of Hellenistic/Roman Sicily
Authors: Prag Jonathan R. W.
Published: January 2022

This paper presents the development of the I. Sicily digital corpus of the inscriptions of ancient Sicily within the context of current debates about open scholarship. The evolution of the I. Sicily project is situated within the framework of Sicilian epigraphic publication and in turn within the framework of humanities publication practices. The approach of the I. Sicily project to open data practices, and the challenges which these pose, is examined through two case studies : the first offering a brief survey of Sicilian epigraphic culture in antiquity ; the second considering the possibilities such datasets and corpora offer for collaborative and progressive research.
Note interpretative e testuali alla col. XXII del Papiro di Derveni
Authors: Lapini Walter
Published: January 2022

This essay deals with some difficult points of Derveni Papyrus Col. XXII : (1) l. 4 : the text is corrupt, read κρατιστεῦόν τε{ ς} λέγουσι instead of κρατιστεύοντες λέγουσι ; (2) l. 6 : πλεονεξία means «arrogance » , not «greed » ; (3) l. 12 : it is impossible to obtain from Δη̣μήτηρ [ Ῥ] έα Γῆ Μή̣τ̣ηρ Ἑστία Δη[ ι] ώι a regular hexameter, as the long quantity of the final alpha of Ἑστία nullifies any effort in this direction ; (4) ll. 13-14 : shall be understood “ Orpheus will clarify this when he comes to the verses (devoted to this subject)”.
La place de la musique dans la politique culturelle de Téos dans la première moitié du IIe siècle avant notre ère
Authors: Perrot Sylvain
Published: January 2022

Quelques inscriptions relatives à la vie musicale de Téos vers 200-160 montrent que les pratiques musicales relèvent d’une politique culturelle proche de celle que les Attalides mettent en oeuvre après Apamée. Si la fondation de Polythrous nous renseigne sur la technicité des disciplines enseignées et le statut socioéconomique des professeurs, qui appartenaient peut-être aux technites installés à Téos, l’instauration du culte pour la défunte reine Apollonis indique que ces pratiques avaient une dimension politique et diplomatique, ce que confirment les concerts donnés par un ambassadeur téien en Crète, où il interprète un répertoire apprécié à la cour pergaménienne.
ПЛАНУВАННЯ ЗРОСТАННЯ ПОТУЖНОСТІ МОРСЬКИХ ПОРТІВ
Authors: Л. Л. НІКОЛАЄВА , В. В. БЕРЕЗА , В. В. СМОЛЕЦЬ
Published: January 2022

У статті наголошується про необхідність планування потужностей портів. Доведено зв’язок конкурентоспроможності порту та збільшення його потужності. Встановлено, що управління потенціалом включає планування та реалізацію потенціалу, а планування потенціалу включає проєктування, оцінку та фінансування. Підкреслено, що пропускна спроможність порту представляє баланс між покращеною якістю обслуговування та впливом на добробут суспільства й інвестиційними витратами на покращення пропускної спроможності.
Preparation, Practice, and Beliefs: A Machine Learning Approach to Understanding Teacher Effectiveness
Authors: Filmer Deon , Nahata Vatsal , Sabarwal Shwetlena
Published: January 2022

This paper uses machine learning methods to identify key predictors of teacher effectiveness, proxied by student learning gains linked to a teacher over an academic year. Conditional inference forests and the least absolute shrinkage and selection operator are applied to matched student-teacher data for Math and Kiswahili from Grades 2 and 3 in 392 schools across Tanzania. These two machine learning methods produce consistent results and outperform standard ordinary least squares in out-of-sample prediction by 14-24 percent. As in previous research, commonly used teacher covariates like teacher gender, education, experience, and so forth are not good predictors of teacher effectiveness. Instead, teacher practice (what teachers do, measured through classroom observations and student surveys) and teacher beliefs (measured through teacher surveys) emerge as much more important. Overall, teacher covariates are stronger predictors of teacher effectiveness in Math than in Kiswahili. Teacher beliefs that they can help disadvantaged and struggling students learn (for Math) and they have good relationships within schools (for Kiswahili), teacher practice of providing written feedback and reviewing key concepts at the end of class (for Math), and spending extra time with struggling students (for Kiswahili) are highly predictive of teacher effectiveness, as is teacher preparation on how to teach foundational topics (for both Math and Kiswahili). These results demonstrate the need to pay more systematic attention to teacher preparation, practice, and beliefs in teacher research and policy.
Pengaruh Kompetensi dan Motivasi Karyawan Terhadap Kinerja Pelayanan Penerbitan Sertifikat Kapal Di Kantor KSOP Khusus Batam
Authors: Malau April Gunawan , Togatorop Agus Leonard , Sabpatari Fardhani
Published: January 2022

Dalam mendukung kinerja pelayanan penerbitan sertifikat kapal di Kantor KSOP Khusus Batam, masih terjadi beberapa masalah pada perusahaan terkait dengan kompetensi dan motivasi karyawan.Masalah tersebut yaitu kurangnya kompetensi tiap karyawan dalam menyelesaikan dan melakukan pekerjaannya, minimnyya motivasi yang terdapat dalam pribadi tiap karyawan dan terjadinya penurunan kualitas kerja.Berdasarkan permasalahan tersebut, penulis melakukan analisis untuk mengetahui apakah ada pengaruh kompetensi dan motivasi karyawan terhadap kinerja pelayanan penerbitan sertifikat kapal di Kantor KSOP Khusus Batam.

 

Jenis penelitian yang digunakan adalah metode kuantitatif. Pengumpulan data dilakukan dengan kuesioner disebarkan langsung ke 30 responden yaitu pada seluruh karyawan KSOP Khusus Batam dengan jumlah pernyataan sebanyak 26 butir. Dalam mencari hasil perhitungan penulis menggunakan program SPSS 25 dan melakukan beberapa analisis data, yaitu: uji validitas dan realibilitas, analisis koefisien korelasi, analisis koefisien determinasi, uji t hitung dan f hitung dan analisis regresi dengan variable intervening. Penarikan kesimpulan dalam penelitian ini dilakukan dengan membandingkan data yang diperoleh dari jawaban responden yang ada.

 

Berdasarkan perolehan data kuesioner dan pengolahan data. Diperolah hasil yang menunjukkan bahwa kompetensi dan motivasi secara bersama-sama terbukti positif dan signifikan terhadap kinerja pelayanan penerbitan sertifikat kapal dengan nilai F hitung > F tabel atau 46,521 > 2,36. Penulis memaparkan beberapa solusi untuk meningkatkan kinerja pelayanan penerbitan sertifikat kapal, yaitu: meningkatkan kompetensi karyawan, meningkatkan motivasi karyawan dan memaksimalkan kinerja perusahaan.
A Tertiary Review on Blockchain and Sustainability with Focus on Sustainable Development Goals
Authors: Jiang Shanshan , Jakobsen Kine , Bueie Jonas , Li Jingyue , Haro Peter Halland
Published: January 2022

 Blockchain as a disruptive technology and a driver for social change has exhibited great potential to promote sustainable practices and help organizations and governments achieve the United Nations’ Sustainable Development Goals (SDGs). Literature reviews on blockchain and sustainability exist, but they often focus only on topics related to one or a few SDGs. There is a need to consolidate existing results in terms of SDGs and provide a comprehensive overview of the impacts that blockchain technology may have on each SDG. This paper intends to bridge this gap, presenting a tertiary review based on 34 existing literature reviews, to investigate the relationship between blockchain and sustainability in light of SDGs. The method used is a consensus-based expert elicitation with thematic analysis. The findings include a novel and comprehensive mapping of impact-based interlinkage of blockchain and SDGs and a systematic overview of drivers and barriers to adopting blockchain for sustainability. The findings reveal that blockchain can have a positive impact on all 17 SDGs through technological innovations though some negative effects can occur and impede the achievement of certain objectives. 73 positive and 10 negative linkages between blockchain adoption and the 17 SDGs as well as 45 factors that drive or hinder blockchain adoption for the achievement of SDGs have been identified. Research gaps to overcome the barriers and enhance blockchain’s positive impacts have also been identified. The findings may help managers in evaluating the applicability and tradeoffs and policymakers in making supportive measures to facilitate sustainability using blockchain. 
Interference in Coupled Structures with Strongly Un-balanced Phase Velocities of Normal Waves and its Electromagnetic Analogy with "Tsunami"
Authors: Malyutin Nickolay , Loschilov Anton , Malyutin George , Sabitov Timur
Published: January 2022

An analogy is drawn between the appearance of tsunami waves and "slow" waves in coupled structures (CS). Tectonic disturbances, as the cause of tsunami generation, generate "fast" waves similar to those in СS. The assumption is made that it is theoretically possible to give a rapid prediction of the occurrence of a natural disaster on the basis of information about the disturbing factor and environmental parameters. The paper notes the obvious problem of the lack of information about the parameters of the initial conditions of excitation of a rapid wave of tectonic origin in the prediction of tsunamis. It is possible that the considered electrodynamics analogy "Tsunami" will allow, firstly, to put and solve the problem of reconstruction of disturbing impact parameters, since the information about it comes before consequences, secondly, to develop "desktop" model of tsunami for some areas, thirdly, to develop measures to protect the coast by creating devices for diversion of tsunami wave energy part in safe directions.
EgoFish3D: Egocentric 3D Pose Estimation from a Fisheye Camera via Self-Supervised Learning
Authors: Liu Yuxuan , Yang Jianxin , Gu Xiao , Chen Yijun , Guo Yao , Yang Guang-Zhong
Published: January 2022

Egocentric
vision has a wide range of applications for human-centric activity recognition.
However, the use of the egocentric fisheye camera allows wide angle coverage
but image distortion is introduced along with strong human body self-occlusion,
which can impose significant challenges in data processing and model
reconstruction. Unlike previous work only leveraging synthetic data for model
training, this paper first presents a new real-world EgoCentric Human Action
(ECHA) dataset. By using the self-supervised learning under multi-view
constraints, we propose a simple yet effective framework, namely EgoFish3D, for
egocentric 3D pose estimation from a single image in different real-world
scenarios.
Small-signal Stability Assessment of Heterogeneous Multi-converter Power Systems
Authors: Zhou Yuhan , Xin Huanhai , Wu Di , Liu Feng , Li Zhiyi , Wang Guanzhong , Yuan Hui , Ju Ping
Published: January 2022

The increasing penetration of renewable resources into the power network through grid-following converters has increased the risks of oscillation instability. In such a power system, it is challenging for
assessing the small-signal stability due to the complex interaction among converters
interconnected through the power network. Moreover, the assessment complexity
is further increased in a heterogeneous multi-converter system, where the
interconnected converters have different control configurations or parameters
from different manufacturers. To tackle the challenges, this paper proposes a
method for the small-signal stability analysis of a heterogeneous
multi-converter system. To this end, it is first theoretically proved that the
small-signal stability of a heterogeneous system can be characterized by an equivalent
homogeneous one, where all interconnected converters have the same control
configurations and parameters. This can reduce the complexity of the small-signal
stability assessment of the original heterogeneous system by decoupling the
equivalent homogeneous system into a set of subsystems. To further reduce the
assessment complexity, it is derived that the small-signal stability and
stability margin of the heterogeneous system can be estimated based on the
smallest eigenvalue of a weighted Laplacian matrix of the power network. Based
on the analysis results, a scalable method is developed for assessing the
small-signal stability of heterogeneous multi-converter systems. The efficacy
of the proposed method is validated by performing both modal analysis and
time-domain simulations on two heterogeneous multiple-converter systems with different
network sizes and converter numbers.
Atuação do enfermeiro na prevenção e cuidado ao paciente com úlcera por pressão na unidade de terapia intensiva
Authors: Felisberto Marcela Pezzin , Takashi Magali Hiromi
Published: January 2022

Objetivo: analisar a assistência da equipe de enfermagem nos cuidados e na prevenção de pacientes com lesões por pressão que se encontram internados na Unidade de Terapia Intensiva, evidenciando a contribuição e importância do enfermeiro no cuidado a esses pacientes. Método: o estudo trata-se de uma revisão de literatura, de abordagem qualitativa, com recorte temporal de 2006 a 2021. Foram selecionados 8 artigos para o estudo, captados na Biblioteca Virtual em Saúde (BVS). Resultados: Os cuidados de enfermagem às úlceras por pressão abrangem intervenções relacionadas ao acompanhamento integral do paciente em risco de adquirir a lesão, por meio da utilização de escalas de predição de risco, conhecimento dos fatores de risco e da realidade das unidades de saúde pelo enfermeiro. Considerações finais: a importância do enfermeiro por meio da prescrição dos cuidados e as intervenções relacionadas ao acompanhamento integral do paciente, é de suma importância à prevenção e ao tratamento das úlceras por pressão como forma de reduzir o tempo de permanência do paciente na Unidade de Terapia Intensiva e, consequentemente, os custos hospitalares, melhorias no prognóstico do paciente e prevenção de infecções.
Descritores: Unidade de Terapia Intensiva; Cuidados de Enfermagem; Úlcera por pressão.
中印中成药功效语的翻译问题分析 ANALISIS KESALAHAN PENERJEMAHAN MANDARIN INDONESIA PADA KHASIAT OBAT JADI TIONGKOK
Authors: JULIANA JULIANA
Published: January 2022

摘要中药在我们现在日常生活中已经非常常见的东西了，尤其中成药非常便捷所以为了能够使更多的印尼人使用中成药，需要一个翻译过程，特别是功效语。本论研究对象是五家中成药进口公司的进口药品，共120 个中成药品，盒子上必须出现中文版与印尼版的功效语，而药品必须在两个国家公用，并且得到印度尼西亚食品与药物监督机构批准。本研究的研究目的得知翻译药物功效语中出现哪些翻译问题。据调查研究，笔者发现中成药功效语翻译里存在着三大问题，即减译问题、增译问题和误译问题，而最常见的中成药功效语翻译问题是减译问题，占63.8%，因为这样的翻译显出更简介，但并不能把原文的信息明确地翻译出来，使有些病症发生了意义上的变化。笔者建议，在翻译功效语中，最好采取直译技巧，因为这样能把原文的消息明确地翻译出来，以免消费者对药品使用产生误会。关键词：中成药、功效语翻译、翻译问题AbstrakPengobatan tradisional Tiongkok merupakan hal yang sangat lazim dalam kehidupankita sehari-hari, apalagi pengobatan obat jadi Tiongkok yang sangat nyaman dipergunakanoleh masyarakat umum, sehingga agar lebih banyak masyarakat Indonesia yang dapatmenggunakan obat jadi Tiongkok diperlukan proses penerjemahan terutama pada khasiatobat tersebut.Subjek karya penulisan ini adalah 120 buah obat jadi Tiongkok dari 5 perusahaanimportir obat jadi Tiongkok, yang dimana pada kotak obat harus tercantum khasiat obatdalam bahasa Mandarin dan bahasa Indonesia, dan obat-obatan tersebut ada di kedua negara,serta telah terdaftar di Badan Pengawasan Obat dan Makanan Indonesia.Tujuan dari karya penulisan ini adalah untuk mengetahui masalah apa saja yang munculdalam menerjemahkan obat. Berdasarkan analisa, peneliti menyadari dalam menerjemahkankhasiat obat terdapat tiga masalah utama penerjemahan, yaitu masalah teknik pengurangan kata, masalah teknik penambahan kata dan masalah distorsi makna, sedangkan masalah yangpaling sering muncul adalah masalah teknik pengurangan kata dengan persentase 63.8%,karena dengan teknik terjemahan ini khasiat obat akan terlihat lebih singkat. Namun,menerjemahkan dengan teknik ini tidak terlalu baik karena informasi aslinya tidakditerjemahkan dengan tepat, bahkan ada beberapa yang mengalami perubahan makna.Penulis menyadari bahwa dalam menerjemahkan khasiat obat, paling baik menggunakanteknik terjemahan literal, karena informasi aslinya dapat diterjemahkan dengan tepat, dankonsumen tidak akan salah paham ketika menggunakan obat.Kata kunci ： Obat Tiongkok ； Teknik Penerjemahan Khasiat Obat ； KesalahanTerjemahan
Biological activity of needle sap of some plants of the order of Pine (Pinales)
Authors: Bushmelewa K. N. , Terenzhev D. A. , Sharonova N. L. , Belov T. G. , Lyubina A. P.
Published: January 2022

The article presents the results of a study of the biological activity of the sap of the needles of Norway spruce ( Picea abies L.), Scots pine ( Pinus sylvestris L.) and Japanese yew ( Taxus cuspidata Siebold et Zucc. Ex Endl.). The highest antimicrobial activity of the Japanese yew’s needle sap against human pathogens and phytopathogens was established: the values minimum inhibitory concentration, the minimum bactericidal concentration and the minimum fungicidal concentration were 0.0313 and 0.0078%, respectively. Expressed antioxidant properties and membrane-protective activity of Scots pine needles sap were revealed in comparison with Norway spruce both in winter and in summer. The Japanese yew needle sap had the most pronounced antioxidant properties. With a decrease in the concentration of Japanese yew needle sap, its ability to protect membranes from peroxide hemolysis increased. Its high cytotoxicity and lack of selectivity in relation to tumor cells have also been established.
Bidara leaf extract (Ziziphus mauritiana) inhibits Metalloproteinase-1 increase and collagen decrease in female Wistar rat skin exposed to Ultraviolet-B and cigarette smoke
Authors: Anggraeny Citra , Wiraguna Anak Agung Gde Putra , Pinatih Gde Ngurah Indraguna
Published: January 2022

Background

Exposure to cigarette smoke and ultraviolet-B can activate enzymes that degrade collagen and inhibit its production through increased levels of MMP-1. Bidara leaves with high content of flavonoids and tannins may prevent damage caused by free radicals. This study aimed to prove the effect of Bidara leaf extract in inhibiting the increase in MMP-1 levels and collagen reduction in female Wistar rat’s skin exposed to UV-B and cigarette smoke.

Methods

A randomized posttest-only control group design study was conducted on 30 female Wistar rats, aged 8-10 weeks, weighing 130-150 grams. The rats were divided into three groups: the group without treatment, the base cream, and the 7.5% Bidara leave extract groups. The last two groups were exposed to UV-B light and cigarette smoke. After four weeks of intervention, the back skin tissue was taken to assess collagen amount and MMP-1 levels. Comparative analysis was performed to see the difference between groups.

Results

The results showed that the mean levels of MMP-1 in the untreated group were lowest, followed by the Bidara leaf extract cream and the base cream group. The mean collagen amount of the Bidara leaf extract group was the highest, followed by the base cream and the untreated group. The analysis showed a significant difference in the mean levels of MMP-1 and collagen amount between groups (p<0.05).

Conclusion

The 7.5% Bidara leaf extract cream inhibited the increase in MMP-1 levels and decreased collagen in female Wistar rats exposed to UV-B light and cigarette smoke.
РОЛЬ АХМАТА-ХАДЖИ КАДЫРОВА В РАЗВИТИИ ОБРАЗОВАНИЯ И КУЛЬТУРЫ В ЧЕЧЕНСКОЙ РЕСПУБЛИКЕ
Authors: Тужуева Х.Х. , Абдуразакова Х.Х.
Published: January 2022

В данной статье рассматривается деятельность А.А. Кадырова в общественно-культурной сфере, анализируется его роль в культурных и образовательных процессах. Анализируется деятельность Ахмата-Хаджи Кадырова как яркой личности и крупного культурно-общественного лидера, внесшего значительный вклад в развитие культуры, возрождение образовательных центров и процветание Республики. Ахмат-Хаджи Кадыров особое внимание уделял восстановлению системы образования, которая была полностью разрушена в ходе боевых действий.