bluuebunny/crossref_metadata_2025 huggingface dataset:
Will Live Streaming Platforms and Influencers Consolidate or Disrupt Democracy?
Authors: Kang Yowei , Yang Kenneth C. C.
Published: November 2021

New communication technologies have enabled politicians to interact and engage with their constituents constantly and unmitigated by mainstream media. Among them, emerging live streaming platforms rise as an essential political communication tool. However, in consolidating politicians' base, these technologies similarly run the risk of polarizing the society, resulting in disruption and healthy development of democracy. This case study describes and examines the role of live streaming platforms and influencers in generating political participation to account for the success of President Tsai Ing-wen's 2020 re-election campaign in Taiwan. This study focuses on the roles of live streaming platforms and influencers in contributing to the growing and alarming global phenomenon of populism and polarization associated with politicians' campaign strategies. This study also discusses whether the employment of live streaming influencers as a viable political communication tool in this campaign may ultimately contribute to the democratic deepening in Taiwan.
Technology Use and Innovation Strategies in Event Tourism
Authors: Türkmendağ Tuba , Türkmendağ Zafer
Published: November 2021

Event tourism has undergone a serious change in the world with developing technology and innovations. In this respect, this chapter examines the direct, marketing, and management effects of technology on event tourism with a literature review. Studies in this field in the literature show that technologies such as artificial intelligence, big data, robots, decision support systems, internet of things, 5G cause behavioral changes in tourists; thus, event organizers use these technologies effectively to keep up with this change. In this context, academic studies in the field, new technologies, and methods used, innovation strategies are explained in detail in the book section, and a framework has been developed and presented to examine smart event tourism in detail. The results of the research are thought to contribute to the literature and offer managerial solutions.
Universities in Developmental Transition
Authors: Dipholo Kenneth , Tshishonga Ndwakhulu Stephen
Published: November 2021

This chapter interrogates the benefits that would accrue to and challenges faced by universities in their developmental transition from being an ivory tower to engaged and people-centered institutions. The chapter argues that universities should consider themselves as vehicles of socio-economic change by participating in the process of forming values and setting reachable goals for the benefit of larger society. University of Botswana (UB) adopted ‘Strategy for Excellence: University of Botswana Strategic Plan to 2016 and Beyond' while the University of KwaZulu-Natal has adopted Strategic Plan 2017-2021 with eight goals. Through these plans, the universities seek to have a more direct impact within communities and society. Community engagement or service learning is adopted as one of the vehicles to fast-track the transition process in this chapter. This chapter is qualitative and has made use of UB and UKZN as the case studies to deliberate the university transition from ivory towers into engaged, responsible, and people-centered institutions.
Ethics and Integrity Training for Czech Public Officials
Authors: Bohata Marie , Putnova Anna , Rasticova Martina , Cebakova Andrea
Published: November 2021

The purpose of the contribution is to present a newly designed training programme for public administrators in ethics and integrity. The programme was developed based on a broad empirical research among public administrators at the central and local levels of public administration aiming at identification of core values, major ethical issues, attitudes, and ethics instruments in place on the one hand and the training needs of civil servants and other public administrators on the other hand. Attention was paid to differences among rank-and-file administrators and managers and to differences between men and women where relevant.
The Importance of Ethics Education in Public Administration Within the Context of Global Challenges
Authors: Ciğeroğlu Öztepe Mısra , Akca Hakan
Published: November 2021

The issue of “ethics,” which is frequently emphasized in the development and transformation processes of public administration (PA) and stands out in the context of combating problems, crises, and corruption in the discipline, is becoming more important in today's global world. In parallel, studies on the place and importance of ethics education in PA have been increasing in recent years, especially with the emphasis on the ability of ethics to provide solutions to these problems. In this context, this study addresses the place and importance of ethics education in PA education and training in the world and in Turkey. In this framework, firstly, the relationship between PA and ethics and the importance of ethics education in PA are examined. After that, the examples of educational institutions providing ethics education in the world and in Turkey and their educational contents are analyzed. The study ends by making a comparison concerning the subject in the world and Turkey and making various suggestions.
Teaching of Foreign Language in the Educational Process of Public Administration Personnel in Ukraine
Authors: Lebedeva Nadezhda Anatolievna
Published: November 2021

The main aim of this chapter is to describe the organizational and methodological foundations of professional education for public servants using modern educational methods. Its scientific novelty is in the description of teaching a foreign language to students of specialities in public administration. It has a character of theoretical representation of the existing methods of teaching a foreign language to students specializing in public administration in Ukraine. It is concluded that foreign language teaching in the process of training public servants is not a key subject, but it does not solve the problem of the need to master it. In this connection, teachers have to highlight certain aspects in the methodology so that professional training coincides with the native language. It is necessary to pay attention to the general language training, and only then introduce professional vocabulary. The relevance of this research is to share an existing experience with colleagues from other countries.
Death and Resurrection on the If Island
Authors: Florent Adriana Coelho
Published: November 2021

The castle of If is one of the most popular tourist attractions in Marseille. This 16th-century fortress was a prison from 1540 until the First World War. Tourists from all over the world are drawn by the presence of a prisoner who has never been there because he never existed: Edmond Dantès, the Count of Monte-Cristo. This chapter analyses how this castle became a confluence space between fiction and reality and a venue for various film adaptations of Dumas' novel. It also shows how this romantic pamphleteer managed to overcome the paradox of giving authenticity to a tourist spot without paying any attention to historical facts or verisimilitude. The chapter draws on the concepts of literary and dark tourism, the concept of aura linked to authenticity in the work of art, and the concept of literary tourist.
Analysis of Budapest as a Film Tourism Destination
Authors: Papp-Váry Árpád Ferenc , Tóth Tímea Zsófia
Published: November 2021

The Hungarian film industry has undergone a huge change recently, becoming a pull sector and repositioning the country in Europe. The economic performance of Budapest's film industry is growing steadily, which has also been facilitated by the strategic steps of recent years, making the capital a key player on the film map of Europe. In the case of Budapest, the diversity of the city is clearly outlined, as it primarily serves as a backdrop for various film productions. Using primary and secondary sources, the research focuses on the supply elements of film tourism in Budapest and the changes in the economic environment affecting the film industry. In the analysis, different types of film tourism are explored through interviews with the actors of film tourism. The research seeks to highlight factors that can boost film tourism in Budapest and make the city even more prominent on the film map of Europe.
From Nuclear Disaster to Film Tourism
Authors: Tóth Tímea Zsófia , Papp-Váry Árpád Ferenc
Published: November 2021

The research explores how a well-known historical location associated with disaster tourism became a destination of film tourism. Thanks to the HBO miniseries, the nuclear accident zone around Chernobyl registered a record number of tourists in 2019. The study includes a complex tourism analysis of Chernobyl. The examination of the demand and supply sides of local film tourism is followed by an analysis of elements such as the number of visitors and the supply of thematic routes. The study also analyses interviews with local travel companies and information on their social media platforms. The clear aim of the research is to find out how a successful film may affect the tourism of a location. Using the results of the research, the study discusses how a site previously associated with disaster tourism utilizes the opportunities of film tourism, as well as the opportunities provided by a possible change of profile.
Future-Proof Transformational School Design for the New Era
Authors: Simmons Mara , Wiltshire Mary
Published: November 2021

The ‘New Era' defined as post pandemic has opened up a conversation for more opportunities to transform school design in order to create a more functional, engaged democratic society premised on a social responsibility reflecting a multicultural, empowered workforce. This chapter is a product of the collaboration of a UK and a US educator looking at two case studies of secondary education and one higher education that serve as examples of success for transforming schools. Using Bolman and Deal's Four Frames for Organizational Design, the authors make the case for school designs that take into account diverse learner groups and diverse pathways leading to an educated and skilled workforce. A result from this analysis includes a specific, short list of components to consider for transforming schools.
ISAR Consensus Guidelines on Add-Ons Treatment in In vitro Fertilization
Authors: Malhotra Jaideep , Malhotra Keshav , Kamat Sudesh , Mishra Akansha , Chatterjee Charulata , Nair Seema , Ghosh Pranay , Mehta Rajvi , Bhadraka Harsha , Srinivas Sapna , Kumar Lalith , Mistry Rushika , Goenka Deepak , Kant Gaurav
Published: November 2021

Study Question:

What are the good practices for the use of ADD-ON Treatments in IVF cycles in INDIA?

What is Already Known:

Add on treatments in IVF are procedures and technologies which are offered to patients in hope of improving the success rates. A lot of add on treatments exist; most of them have limited evidence and data for the Indian patient population is miniscule. These interventions may have limited effects, so it is imperative that any new technology that is offered is evaluated properly and has enough evidence to suggest that it is safe and effective.

Study Design, Size, Duration:

This is the report of a 2-day consensus meeting where two moderators were assigned to a group of experts to collate information on Add on treatments in IVF in INDIA. This meeting utilised surveys, available scientific evidence and personal laboratory experience into various presentations by experts on pre-decided specific topics.

Participants/Materials, Setting, Methods:

Expert professionals from ISAR representing clinical and embryology fields.

Main Results and the Role of Chance:

The report is divided in various components including the health of the Offspring, the various ADD ons available to an ART center, consensus points for each technology & qualifications and trainings for embryologists, the report and recommendations of the expert panel reflect the discussion on each of the topics and try to lay down good practice points for labs to follow.

Limitations, Reasons for Caution:

The recommendations are solely based on expert opinion. Future availability of data may warrant an update of the same.

Wider Implications of the Findings:

These guidelines can help labs across the country to standardise their ART services and improve clinical outcomes, it will also motivate clinics to collect data and report the use of Add ons to the national registry.

Study Funding/Competing Interest(S):

The consensus meeting and writing of the paper was supported by funds from CooperSurgical India.
Circulating follicular T-helper cells in patients with nonsegmental vitiligo
Authors: Rezk Hassan Ghada Fawzy , Abdel-Dayem MennatAllah Mohammed , Saad Mohammed Attia , Hegab Doaa Salah
Published: November 2021

Vitiligo is a common depigmenting dermatosis with an autoimmune background. Circulating T-follicular helper (Tfh) cells are reported to increase and correlate with disease activity and autoantibody production in several human autoimmune diseases. The potential contribution of Tfh cells in vitiligo pathogenesis has not been well elucidated yet. Hence, this study aimed to evaluate the frequency of circulating Tfh cells in patients with nonsegmental vitiligo (NSV) in comparison to normal healthy subjects to detect their possible role in vitiligo pathogenesis. Venous blood samples were obtained from 25 patients with NSV and 20 age- and sex-matched healthy controls to determine the level of circulating Tfh cells (CD3+ CD4+ CXCR5+ PD-1+ T cell population), by flowcytometry. The frequency of peripheral CXCR5+ PD-1+ lymphocytes which are CD3+ CD4+ was significantly augmented in vitiligo patients than controls. It showed a significant positive correlation with vitiligo disease severity and activity estimated by Vitiligo Area Scoring Index and Vitiligo Disease Activity scores, respectively. These results emphasize on the potential role of Tfh cells in the pathogenesis, extent, and severity of NSV. Antagonizing the autoimmune initiating action of Tfh cells population or targeting their cytokine secretion might offer a helpful future tool for the treatment of patients with NSV particularly in active cases.
Prevalence and Clinicopathologic Risk Factors for Epidermal Growth Factor Receptor, Anaplastic Lymphoma Kinase, and ROS-1 Fusion in Metastatic Non-Small Cell Lung Carcinoma
Authors: Kesri Raghav , Goyal Hari , Gupta Geetanjali , Bharti Deepak , Sharma Richu
Published: November 2021

Purpose:

The purpose of he study was to evaluate the prevalence of epidermal growth factor receptor (EGFR) mutations, anaplastic lymphoma kinase (ALK), and ROS-1 fusions in the patients with metastatic nonsquamous nonsmall cell lung carcinoma (NSCLC) and their relation with different demographic and clinical variables.

Methods:

A cross-sectional study was carried out on 87 adult patients >18 years of age with a confirmed diagnosis of Stage IV metastatic NSCLC. All the patients were studied for EGFR mutations, ALK, and ROS-1 fusions. The outcome measures were the presence of EGFR, ALK, and ROS-1 fusions among the patients with NSCLC and the risk association with age, gender, smoking, and tumor differentiation.

Results:

Out of 87 patients, 26 (29.89%) patients tested positive for EGFR mutations, 4 (4.6%) for ALK, and a single case for ROS-1 fusion. The mean age of the patients who were EGFR positive was significantly younger than the mean age of those without EGFR mutation (56.77 ± 12.01 vs. 66.69 ± 11.34, P = 0.0004). As for the gender, females had significantly more EGFR mutations (53.85% vs. 46.15%, P = 0.013) with an odds ratio (OR) of 3.281 (1.257–8.562). Ex-smokers or nonsmokers showed an increased risk of EGFR mutation with an OR of 87.212 and 38.405 (P < 0.0001). There was no association of histology or grading with EGFR mutation. ALK and ROS-1 showed no significant association with clinical variables (P > 0.05).

Conclusion:

EGFR mutation is the most common occurrence in NSCLC, with other minor mutations being ALK fusion and ROS-1 rearrangements. Females, young age, and nonsmoking behavior carry a significantly higher risk of EGFR mutation, which usually confers a good prognosis.
Effect of type 1 tympanoplasty on the quality of life of patients suffering from chronic otitis media (safe type)
Authors: Devi KJ , Singh M , Maan AS , Thomas O , Kaur G , Arya S , Kaur J
Published: November 2021

Background:

Chronic otitis media (COM) remains a major public health issue and is associated with relentless discharge from the ear, pain, significant functional limitation of hearing, leading to communication problems and frequent specialist visits.

Aims:

To assess the improvement in quality of life of patients of COM (safe type) and surgical success in terms of graft uptake and improvement in hearing.

Patients and Methods:

A prospective questionnaire-based outcome study was directed in 100 patients with COM who were treated with Type I Tympanoplasty at our institution between May 2018 and May 2020. All patients were asked to fill Modified Chronic Otitis Media 4 (COM-4) survey before operation and 3 months after operation. Preoperative and postoperative total ear scores, audiological results, postoperative graft uptake were assessed.

Results:

The correlation between preoperative and postoperative assessment by questionnaire was statistically critical (P < 0.001). There was significant improvement in hearing postoperatively (P < 0.001). Effective graft uptake was seen in 80%.

Conclusion:

The current study emphasizes that Type 1 Tympanoplasty fundamentally improves quality of life of patients in terms of physical suffering, hearing loss, emotional distress postoperatively.
Prognostic significance of the metastatic lymph node ratio compared to the TNM classification in stage III gastric cancer
Authors: Gulmez S , Senger A S , Uzun O , Omeroglu S , Ofluoglu C , Sert Z O , Oz A , Polat E , Duman M
Published: November 2021

Background:

We aimed to evaluate a comparative analysis of the prognostic value of the metastatic lymph node ratio (LNR) and pN (TNM) in stage III gastric cancer.

Patients and Methods:

A total of 159 stage III gastric cancer patients with curative gastrectomy were retrospectively analyzed. Cutoff values for LNR were designated according to 25%, 50% and 75% percentiles, 0.07, 0.20 and 0.44 respectively. The LNR was divided into four groups as 0 > LNR1 ≤ 0.07; 0.07 > LNR2 ≤0.20; 0.20 > LNR3 ≤0.44; 0.44 > LNR4 ≤1.

Results:

The mean age of the patients was 61.1 ± 11.3 years. Male predominance was apparent (73.6%). The 1-year overall survival and recurrence rates were 73.6% and 33.6%, respectively. The univariate cox regression analysis demonstrated age and LNR were the main variables that affected overall survival (OS) (p < 0.05). Harvested lymph nodes less than 16 did not affect OS (p = 0.255). The results of the multivariate cox regression analysis revealed that only LNR was an independent prognostic factor (P < 0.001), while pN was not (p > 0.05). Similar results, as with overall survival, could not be revealed clearly for disease free survival (DFS).

Conclusions:

LNR was an independent significant prognostic factor and superior to pN staging in predicting OS but not for DFS in stage III gastric cancer patients. The high LNR levels in our research were found to be associated with poor survival rates. The percentile system we used to determine cutoff values may be considered as a reliable method. Similarly, LNR also provides a reliable prognostic parameter in future staging systems to help guide treatment algorithm plans.
Prevalence study for postoperative nausea vomiting
Authors: Canakci E , Catak T , Basar HE , Cebeci Z , Coskun I , Saltali AO , Altinbas A
Published: November 2021

Background:

Simplified risk models, such as the Apfel score, have been developed to calculate the risk of postoperative nausea-vomiting (PONV) for adult patients. In the absence of any risk factors, PONV risk is assumed to be 10%. While the presence of one of the four risk factors determined as female gender, non-smoking, PONV/car sickness history, and postoperative opioid use is associated with 20% risk for PONV, the risk increases by 20% with the addition of each risk factor, and reaches to 80% if four factors are present.

Aim:

Our aim in this study is to investigate the prevalence of PONV, and whether the scoring systems used for nausea-vomiting in the literature are still valid.

Patients and Methods:

Five groups of patients were included in the study with an Apfel score of 0, 1, 2, 3, 4. Each case was taken to the recovery room at the end of the operation. They were observed whether had nausea-vomiting was recorded according to the Abramowitz emesis score.

Results:

While the PONV risk for women is 24.637 times higher than men, the PONV risk of those who had gynecological surgery is 6.27 times higher than that of the other type of surgery. Those who had urological surgery are 0.345 times less than the other type of surgery. Those who had lower abdominal surgery had a risk of PONV of 4.56 times higher than the others. As the duration of the case increases, the risk of PONV increases 1.01 times (P values P < 0.001, P < 0.001, P < 0.001, P = 0.048, P < 0.001, respectively).

Conclusion:

As a result, our PONV prevalence is considerably lower than the frequency rates mentioned in the literature. PONV scoring systems need long-term studies with larger populations to be updated.
Mandibular neurofibroma with osseous deformities in a 3-year-old child with neurofibromatosis type 1
Authors: Aloyouny AY , Albagieh HN , Alweteid AS , Alsheddi MA
Published: November 2021

Neurofibromatosis type 1 (NF1) is a rare autosomal dominant genetic disorder. It is a multisystem neurocutaneous condition represented by multiple benign tumors of the nerves and skin known as neurofibromas and cafe' au lait spots. However, neurofibroma localized in the mandible is rare. We present a case of a 3-year-old, Egyptian girl with NF1. The girl presented with right mandibular swelling of undetermined duration and multiple hyperpigmented spots on the skin. This case report shows the important role of dentists, as demonstrated in the present case, in the diagnosis and management of this disease, since the diagnosis was made during dental consultation and subsequently managed by the team.
Variations in utilization of health facilities for information and services on sexual and reproductive health among adolescents in South-East, Nigeria
Authors: Agu IC , Mbachu CO , Ezenwaka U , Okeke C , Eze I , Arize I , Ezumah N , Onwujekwe O
Published: November 2021

Background:

Adolescents' sexual and reproductive health has an important influence on a country's long-term national growth. There is a high level of burden due to poor adolescent sexual and reproductive health (ASRH) in Nigeria, especially the Ebonyi State. Evidence shows that in the Sub-Saharan African region, most adolescents experience poor access to information and other services relating to their sexual and reproductive health. Many cultures in Africa see matters around sex and sexuality as social taboos.

Aims:

This study aimed to access variations in the utilization of health facilities for sexual and reproductive health information and services among adolescents in the Ebonyi State, Nigeria. This will inform the design of interventions to improve ASRH.

Patients and Methods:

A total of 1,057 in-school and out-of-school adolescents aged 13–18 years were selected using cluster sampling of households from the six selected local government areas (LGAs) in this cross-sectional survey. Structured questionnaires were used to collect data. Descriptive statistics were performed alongside stratification analysis. Tabulation, bivariate and multivariate logistic regression analyses were undertaken. A household wealth index was calculated using the total household consumption calculated divided by the number of people in the household (per capita household consumption). The per capita household consumption was used to categorize the households into socioeconomic quintiles. The variable was used to differentiate key variables into socioeconomic quintile equity analysis.

Results:

A majority of the respondents had never visited any type of health facility to receive either sexual and reproductive health (SRH) information (90.2%) or services (97.1%). The utilization rate of health facilities for SRH information was 9.8% while for other SRH services was 2.8%. The patent medicine vendor (PMV) was the most visited type of facility for SRH information and other services. Schooling was a strong predictor of health facilities' utilization for SRH information (P < 0.01) and other services (P < 0.01).

Conclusion:

Utilization of health facilities for information and services among adolescents in the Ebonyi State is very low and favorable toward informal service providers such as PMVs. The establishment and strengthening of the existing youth-friendly centers, school clinics, and occasional outreach programs designed specifically to target adolescents would perhaps improve adolescents' access to adequate information and health facility utilization for sexual, reproductive, and health services.
Comprehensive evaluation of factors that induce gingival enlargement during orthodontic treatment
Authors: Almansob YA , Alhammadi MS , Luo XJ , Alhajj MN , Zhou L , Almansoub HA , Mao J
Published: November 2021

Background:

Gingival enlargement (GE) is one of the most common soft tissue problems encountered during fixed orthodontic treatment. Aims: This study aimed to evaluate the factors affecting GE in adolescents and young adults, compared with their normal peers.

Subjects and Methods:

This is a cross-sectional comparative study. The sample consisted of 329 subjects (ages 10–30 years) of both genders, which was divided into four main groups: The control group (G0) with no orthodontic treatment; subjects who underwent orthodontic treatment were divided according to treatment duration into G1 (4–12 months), G2 (13–24 months), and G3 (>24 months). The clinical examinations included the level of debris, calculus (simplified oral hygiene), and GE indices. Regression analyses were used to assess the GE association in all the studied groups.

Results:

The mean GE score increased significantly with increased treatment duration (0.42 ± 0.29 for G0 and 1.03 ± 0.52 for G3). GE scores of the lower arch were significantly higher in the anterior segment than in the posterior segment among all treatment groups. Regression analysis revealed that gender, age, oral hygiene, and treatment duration had a significant effect on GE (P < 0.05), while angle classification, overjet, overbite, treatment stage, bracket type, and therapeutic extraction did not show significant associations (P > 0.05).

Conclusion:

Gender, age, oral hygiene, and treatment duration were the most important risk factors for GE during fixed orthodontic treatment.
High-dose dual therapy versus bismuth-containing quadruple therapy for the treatment of Helicobacter pylori infection – A review of the strengths, weaknesses, and proposed solutions
Authors: Hu Chi-Tan
Published: November 2021

Helicobacter pylori is the principal cause of peptic ulcers, gastric cancer, and mucosa-associated lymphoid tissue lymphoma. The first treatment to H. pylori infection is dual therapy (a bismuth compound plus metronidazole). On the launch of omeprazole in 1988, dual therapy became omeprazole and amoxicillin (low dose). The poor H. pylori eradication rates by either bismuth-based or low-dose dual therapy drove more combinations of antibiotics were needed. Antibiotic resistance, especially clarithromycin and metronidazole, has made bismuth-containing quadruple therapy (BCQT) a savior for first-line and second-line treatments. However, its complicated dosing regimen commonly causes more adverse events and poor drug compliance. Thus, high-dose dual therapy (HDDT) has been re-arising. This article reviews the strengths and weaknesses of HDDT versus BCQT with proposed solutions.
TTF1-positive SMARCA4/BRG1 deficient lung adenocarcinoma
Authors: Mehta Anurag , Diwan Himanshi , Bansal Divya , Gupta Manoj
Published: November 2021

SMARCA4/BRG1-deficient lung adenocarcinoma (SD-LUAD) is being recognized as a distinct subtype based on subtle differences in its clinical, morphological, and immunophenotypic attributes compared to other non–small cell lung carcinomas. We present here a case of SD-LUAD with curious thyroid transcription factor 1 (TTF1) expression in a morphologically heterogenous lung adenocarcinoma. The better differentiated area showed preservation of TTF1 expression, and a poorly differentiated tumor had loss of TTF1 expression with universal BRG1 loss.
Composite follicular lymphoma and classic Hodgkin lymphoma
Authors: Kim Han-Na , Jeon Min Ji , Yu Eun Sang , Kim Dae Sik , Choi Chul-Won , Ko Young Hyeh
Published: November 2021

Composite lymphoma is very rare and a combination of Hodgkin lymphoma and non-Hodgkin lymphoma and even histiocytic tumors can occur. Because of the unfamiliarity, not only can this cause diagnostic problems, but can also affect treatment plan. We report a case of composite lymphoma in a 40-year-old male. Initial biopsy showed a composite lymphoma of follicular lymphoma grade 1 and classic Hodgkin lymphoma. After chemotherapy, another lymph node was taken because of disease progression, which revealed follicular lymphoma, grade 3a without Hodgkin lymphoma component.
Group partition categories
Authors: Nyobe Likeng Samuel , Savage Alistair
Published: November 2021

To every group

G

we associate a linear monoidal category

\mathcal{P}\textit{ar}(G)

that we call a
group partition category
. We give explicit bases for the morphism spaces and also an efficient presentation of the category in terms of generators and relations. We then define an embedding of

\mathcal{P}\textit{ar}(G)

into the group Heisenberg category associated to

G

. This embedding intertwines the natural actions of both categories on modules for wreath products of

G

. Finally, we prove that the additive Karoubi envelope of

\mathcal{P}\textit{ar}(G)

is equivalent to a wreath product interpolating category introduced by Knop, thereby giving a simple concrete description of that category.
Case Report: Dengue Hemorrhagic Fever with Ischemic Stroke
Authors: Basnayake Basnayake Wasala Mudiyanselage Kuma , Somaratne Kaluachchi Gamage Samanthi Kumari , Goonetilleke Chathuri Udeshika , Tilakaratna Pattiniya Markkala Yasoma Indrani , Ranawaka Udaya Kumara
Published: November 2021

Several neurological manifestations are recognized in dengue infection, but stroke is a rare complication. We report a case of ischemic stroke in a patient with dengue hemorrhagic fever. A 52-year-old previously healthy male presented with a history of fever for 2 days, and left-sided weakness and numbness of sudden onset. MRI scanning showed a right-sided thalamic lacunar infarct. Diagnosis of dengue fever was made based on leuco-thrombocytopenia, positive dengue nonstructural protein-1 (NS-1) antigen, and positive dengue IgM antibodies. Severity of limb weakness correlated with the critical phase of dengue hemorrhagic fever (DHF). He was discharged home with good recovery from neurological symptoms and disability. Strokes are rare in dengue, and are mainly hemorrhagic strokes related to thrombocytopenia. Ischemic stroke is even rarer. More evidence is needed for confirmation of dengue as a pathogenic mechanism of ischemic stroke.
Assessment of Knowledge, Attitude, and Practice among Saudi Residents Regarding Hepatitis E Virus
Authors: Althobaiti Shaima O. , Alhumaidi Ghaida O. , Alwagdani Waad M. , Almaroani Kawther M. , Altowairqi Batool S. , Alhaddad Mahmoud S. , Abdelwahab Sayed F.
Published: November 2021

Global data, including those from Saudi Arabia, that examined public knowledge, attitudes, and practices (KAP) toward hepatitis E virus (HEV) are limited. This study examined KAP levels of the general population in Saudi Arabia toward HEV. A cross-sectional study was conducted among 768 participants. An Arabic electronic questionnaire that contained demographic data and had 35 questions was used to measure KAP of the participants concerning HEV. Collected data were analyzed at a significance level of 0.05. A total of 768 individuals participated in the study, of whom 16.3% (N = 125) were males and 83.7% (N = 643) were females. Study subjects were 18 years and above. Most of the participants were Saudi citizens (95.6%; N = 734), and from Western Saudi Arabia (76.4%; N = 587). Thirty-four percent (N = 261) of the participants had not heard of HEV, and 48% were aware that yellowish skin or eyes are the most important sign of hepatitis. The level of participants’ knowledge about HEV was low (39.5%). However, positive attitudes and practices were apparent and tended to aim at how to avoid becoming infected with HEV. In conclusion, the level of HEV-related knowledge among the participants was low, and their practices and attitudes were aimed at avoiding HEV infection. Awareness campaigns are required to increase the public’s HEV-related knowledge.
Collision Reconstruction Methodologies Volume 10A: Pedestrian Collisions
Authors:   Mecanica Scientific Svcs Corp.
Published: November 2021

The last ten years have seen explosive growth in the technology available to the collision analyst, changing the way reconstruction is practiced in fundamental ways. The greatest technological advances for the crash reconstruction community have come in the realms of photogrammetry and digital media analysis. The widespread use of scanning technology has facilitated the implementation of powerful new tools to digitize forensic data, create 3D models and visualize and analyze crash vehicles and environments. The introduction of unmanned aerial systems and standardization of crash data recorders to the crash reconstruction community have enhanced the ability of a crash analyst to visualize and model the components of a crash reconstruction. Because of the technological changes occurring in the industry, many SAE papers have been written to address the validation and use of new tools for collision reconstruction. Collision Reconstruction Methodologies Volumes 1-12 bring together seminal SAE technical papers surrounding advancements in the crash reconstruction field. Topics featured in the series include: • Night Vision Study and Photogrammetry • Vehicle Event Data Recorders • Motorcycle, Heavy Vehicle, Bicycle and Pedestrian Accident Reconstruction The goal is to provide the latest technologies and methodologies being introduced into collision reconstruction - appealing to crash analysts, consultants and safety engineers alike.
Corporate Social Responsibility and Reciprocity Relations during Covid-19
Authors: Raniero Christian , Modarelli Giuseppe
Published: November 2021

This research work opens an interpretative view on corporate social responsibility (CSR) during an unexpected emergency reality and latent environmental collapse as a strategy to survive. The investigation approach follows the lines of a field analysis survey based on 288 consumers before (n=80) and during the spread of Covid-19 (n=208). The study aims to provide paradigms and interpretations of evidence-based CSR as a balanced reciprocity relationship in coping emergencies; this necessarily moved the authors to investigate the relationship transversally, examining the role of budgeting and its repercussions on well-being by hierarchical leadership. Specifically, the authors investigate the existence of possible niches of actions based on cooperative and responsible operations during emergencies.
An Approach to the Quality of Drinking Water as a Matter of Multicriterial Decision
Authors: Bucur Amelia , Lopez-Bonilla Jose L.
Published: November 2021

The aim of the present paper is to approach the matter of water quality by resorting to the metod of multicriterial mathematical programming. MicrosoftExcel enables the simulation of a mathematical model. Furthermore, we have also created a file in the C++ software, in view of the simulation process, applicable to numberless properties of water quality. The case study presents the simulation of a multicriterial analysis of water quality in Sibiu county. This particular study shows the means of obtaining more information about water quality, subsequent to the analysis of its characteristics resorting to statistical analysis-specific software, e.g. SPSS 16 software. Given the increase of drinking water worldwide by tens of percentage points in cca two decades, the author(s) consider(s) that an approach to the quality management of drinking water should represent a key priority of society.
Anaerobic Degradation of Dairy Wastewater in Intermittent UASB Reactors: Influence of Effluent Recirculation
Authors: Silva A. , Capela I. , Arroja L. , Nadais H.
Published: November 2021

This work studied the influence of effluent recirculation upon the kinetics of anaerobic degradation of dairy wastewater in intermittent UASB (Upflow Anaerobic Sludge Bed) reactors. Several laboratory-scale tests were performed with different organic loads in a UASB reactor inoculated with flocculent sludge from an industrial wastewater treatment plant. The data obtained were used for determination of specific substrate removal rates and specific methane production rates and adjusted to kinetic models. A high initial substrate removal was observed in all tests due to adsorption of organic matter onto the anaerobic biomass which was not accompanied by biological substrate degradation as measured by methane production. Initial methane production was about 45% of initial soluble and colloidal substrate removal rate. This discrepancy was observed mainly in the first day of all experiments and was attenuated in the second day. Effluent recirculation raised significantly the rate of removal of soluble and colloidal substrate and methane productivity as compared to literature results for batch assays without recirculation.
¿Realmente theft quiere decir hurto? y otras equivalencias dudosas entre las definiciones legales y criminológicas de las infracciones: Consecuencias para el estudio de la delincuencia
Authors: Linde Antonia , Aebi Marcelo
Published: November 2021

Este artículo analiza la comparabilidad de las definiciones de las infracciones utilizadas en la literatura científica y la investigación en criminología comparada —provenientes de la tradición anglosajona del common law— con aquellas utilizadas en el Código Penal Español (CPE), que provienen de la tradición del derecho continental. El análisis demuestra que la definición criminológica en inglés de algunas infracciones incluidas en el European Sourcebook no tiene un equivalente directo en el CPE, y viceversa. Las principales diferencias provienen de la clasificación y definición de los hurtos y robos en el CPE —similar por cierto a las de diversos códigos latinoamericanos— que implica que los conceptos legales de fuerza y violencia no sean sinónimos de los términos force y violence, lo que conlleva incompatibilidades con conceptos como theft y burglary, y afecta a la distinción entre delitos contra el patrimonio (robo) y contra la persona (robbery). Algunas de estas divergencias tienen un impacto directo sobre las comparaciones internacionales de diversas tasas de delincuencia y podrían haber pasado desapercibidas en muchos de las traducciones de textos en inglés utilizados para la enseñanza de la Criminología.
Prioritising Foodborne Disease with Multi-Criteria Decision Analysis
Authors: Linke Ethan , Mahmoudzadeh Nazmina , Holland Darren
Published: November 2021

In recent years, the FSA has published a series of research projects which have produced estimates of the frequency and burden of thirteen different foodborne diseases. This document outlines the methodology and results of a multi-criteria decision analysis (MCDA) used to rank them in order of their detrimental effect on UK society.
TRANSITION METAL ION COMPLEXES AS POTENTIAL ANTITUMOR AGENTS
Authors:   Faculty of Science, University of Kragujevac, Petrović Biljana
Published: November 2021

Discovery of the antitumor activity of platinum complex, cisplatin, cis-Pt(NH3)2Cl2, and later carboplatin and oxaliplatin, led to the intensive investigation of the potential antitumor activity of the huge number of platinum complexes. Furthermore, it is well-known that platinum complexes express toxicity, numerous side effects and resistance, so the scientists make a lot of efforts to synthetize, beside Pt(II) and Pt(IV), other non-platinum compounds with potential antitumor activity, such as Pd(II), Ru(II/III) and Au(III) complexes. The goal of this study is to summarize the results of the investigation of the interactions between some mononuclear, homo- and hetero-polynuclear Pt(II), Pd(II), Ru(II/III) and Au(III) complexes with different sulfur- and nitrogen-donor biologically relevant nucleophiles. Among mononuclear complexes, the compounds with aromatic terpy (tepyridine) or bpma (bis-(2- pyridylmethyl)amine) and aliphatic dien (diethylentriamine) nitrogen-containing inert ligands were studied. Different homo- and hetero-polynuclear complexes with pz (pyrazine) or 4,4’-bipy (4,4’- bipyridine) as bridging and mostly en (ethylenediamine), bipy (2,2’-bipyridine) and dach (trans-1,2- diaminocyclohexane) as inert ligands were studied as well. The research was focused on the connection between the structure and the mechanisms of interactions with different biomolecules, such as L- cysteine (L-Cys), L-methionine (L-Met), tripeptide glutathione (GSH), guanosine-5’-monophosphate (5’-GMP), DNA and bovine serum albumin (BSA). Some of these complexes were selected for in vitro studies of the cytotoxicity on different tumor cell lines. Observed results contribute a lot as a guidance for the future design and determination of the structure-activity relationship (SAR) of different transition metal ion complexes.
ELECTROPHILIC ORGANOSELENIUM COMPOUNDS AND SARS-COV-2: PRO-OXIDANT ACTIVITY AS A MORE PROMISING WAY TOWARDS THE DRUGGABILITY
Authors:   University of Perugia, Italy, Santi Claudio , Sancineto Luca , Mangiavacchi Francesca , Scimmi Cecilia , Misra Sougat
Published: November 2021

Ebselent has been recently reported as the most efficient hinibitors of Sars-Cov-2 main protease (Mpro) thought the electrophilic covalent pro-oxidation of the reactive Cysteine 145. According to similar evidences in literature we can propose a general mechanism to explore a novel and promising application of mild organoselenium centered electrophiles in medicinal chemistry. New insights in the field of covalent and non-covalent inhibition of Mpro as well as the antiviral SARS-Cov2 activity of novel organoselenium compounds will be here discussed
DEVELOPMENT OF FEDERATED LYMPHOMA CLASSIFICATION MODELS ACROSS MULTIPLE HARMONIZED COHORTS OF PATIENTS WITH PRIMARY SJÖGREN’S SYNDROME
Authors:   Department of Informatics, University Campus of loannina, Greece., Exarchos Themis
Published: November 2021

Primary Sjögren’s Syndrome (pSS) is a chronic autoimmune disease followed by exocrine gland dysfunction, where it has been long stated that 5% of pSS patients are prone to lymphoma development. In this work, we present a federated AI (artificial intelligence) strategy which enables the federated training and validation of AI algorithms for lymphoma classification across 21 European cohorts with pSS patients. Advanced AI algorithms were developed, including federated gradient boosting trees with and without dropouts, federated Multilayer Perceptron and federated Multinomial Naïve Bayes. Two large-scale case studies were conducted to demonstrate the applicability and robustness of the federated AI models, where emphasis is given on class imbalance handling and explainability analysis. The federated gradient boosting trees with dropouts achieved the best classification performance yielding more than 0.8 sensitivity and specificity along with 5 biomarkers as prominent for lymphoma development and progression.
APPLICATION OF ARTIFICIAL INTELLIGENCE-BASED IMAGE ANALYSIS IN BIOINFORMATICS
Authors:   Faculty of Engineering Rijeka, University of Rijeka, Croatia, Car Zlatan , Anđelić Nikola , Lorencin Ivan , Musulin Jelena , Štifanić Daniel , Baressi Šegota Sandi
Published: November 2021

The collection of image data is an extremely common procedure in clinical practice today. Many of the diagnostic approaches generate such data – computed tomography (CT), X-ray radiography, magnetic resonance imaging (MRI), and others. This data collection process allows for the use of computer vision approaches to be applied with the goal of analysis and diagnostics. Artificial Intelligence (AI) based algorithms have repeatedly been shown to be the best performing computer vision algorithms, in many fields including medicine. AI-based – or more precisely machine learning (ML) based, algorithms have capabilities which allow them to learn the patterns contained in the data from the data itself. Among the best performing algorithms are artificial neural networks (ANNs), or more precisely convolutional neural networks (CNNs). Their pitfall is the need for the large amounts of data – but as it has been previously mentioned, the amount of data collected in today’s clinical practice is large and ever increasing. This allows for the development of Smart Diagnostic systems which are meant to serve as support systems to the health professionals. In this paper first, the standard practices and review of the field is given – with the focus on challenges and best practices. Then, multiple examples of the research applying AI-based algorithm analysis are given – including diagnostics of various cancer types (bladder and oral) as well as COVID-19 severity diagnostics and image quality determination.
MODE SELECTION BY OHMIC LOSSES IN LONGITUDINALLY CORRUGATED CAVITIES OF SUB-THz SECOND-HARMONIC GYROTRONS
Authors: Tkachova T.I. , Shcherbinin V.I. , Tkachenko V.I.
Published: November 2021

Ohmic wall losses are proposed as a means for improving the mode selection in a cylindrical gyrotron cavity with longitudinal wedge-shaped corrugations. Such losses depend on mode frequency and geometrical parameters of the corrugations. For cavity of the 0.4-THz second-harmonic gyrotron we find the corrugation depth, which corresponds to maximum ohmic losses of the competing modes excited at the first (fundamental) cyclotron resonance, as well as to reasonably low losses of the operating mode. For this depth, we determine the number of corrugations and their width, which ensure the maximum enhancement of the ohmic wall losses of the fundamental modes with respect to those of the operating second-harmonic mode, together with minimum conversion of the operating second-harmonic mode to higher Bloch harmonics. Parameters of the corrugations in hand are practicable.
EFFECT OF TRANSITION RADIATION AND DISPERSION SPREADING AT ACHIEVEMENT OF A LARGE TRANSFORMER RATIO OF DRIVER-BUNCH ENERGY INTO WAKEFIELD IN A DIELECTRIC RESONATOR ACCELERATOR
Authors: Maslov V.I. , Bondar D.S. , Onishchenko I.N. , Papkovich V.G.
Published: November 2021

Possibility of increase of transformer ratio TR in the case of the profiled sequence of bunches at their injection in a two-beam electron-positron dielectric-resonator collider is considered. Unlike considered earlier the waveguide case, for which TR is equal to the doubled number of bunches of sequence which provide a contribution to the total wakefield, and which is limited by the effect of the group velocity, in a resonator this limitation is absent. For derivation in the case of resonator of TR, proportional to the number of bunches, as well as in the waveguide, the ratio of bunch charges is selected to be equal 1:3:5: … , lengths of bunches, equal to the half of wavelength, interval between bunches is multiple to the wavelength. The effect of transition radiation and dispersion spreading on the transformer ratio is studied by numerical simulation.