bluuebunny/crossref_metadata_2025 huggingface dataset:
Identification of Key Genes and Pathways in the Hippocampus after Traumatic Brain Injury: Bioinformatics Analysis and Experimental Validation
Authors: Zeng Hai , Zhao Sisi , Pang Zhao , Wang Shiqi , Cao Luxi , Zhang Yimin
Published: February 2023

Background: Traumatic brain injury (TBI) is a common brain injury with a high morbidity and mortality. The complex injury cascade triggered by TBI can result in permanent neurological dysfunction such as cognitive impairment. In order to provide new insights for elucidating the underlying molecular mechanisms of TBI, this study systematically analyzed the transcriptome data of the rat hippocampus in the subacute phase of TBI. Methods: Two datasets (GSE111452 and GSE173975) were downloaded from the Gene Expression Omnibus (GEO) database. Systematic bioinformatics analyses were performed, including differentially expressed genes (DEGs) analysis, gene set enrichment analysis (GSEA), Gene Ontology (GO) enrichment analysis, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis, protein-protein interaction (PPI) network construction, and hub gene identification. In addition, hematoxylin and eosin (HE), Nissl, and immunohistochemical staining were performed to assess the injured hippocampus in a TBI rat model. The hub genes identified by bioinformatics analyses were verified at the mRNA expression level. Results: A total of 56 DEGs were shared in the two datasets. GSEA results suggested significant enrichment in the MAPK and PI3K/Akt pathways, focal adhesion, and cellular senescence. GO and KEGG analyses showed that the common DEGs were predominantly related to immune and inflammatory processes, including antigen processing and presentation, leukocyte-mediated immunity, adaptive immune response, lymphocyte-mediated immunity, phagosome, lysosome, and complement and coagulation cascades. A PPI network of the common DEGs was constructed, and 15 hub genes were identified. In the shared DEGs, we identified two transcription co-factors and 15 immune-related genes. The results of GO analysis indicated that these immune-related DEGs were mainly enriched in biological processes associated with the activation of multiple cells such as microglia, astrocytes, and macrophages. HE and Nissl staining results demonstrated overt hippocampal neuronal damage. Immunohistochemical staining revealed a marked increase in the number of Iba1-positive cells in the injured hippocampus. The mRNA expression levels of the hub genes were consistent with the transcriptome data. Conclusions: This study highlighted the potential pathological processes in TBI-related hippocampal impairment. The crucial genes identified in this study may serve as novel biomarkers and therapeutic targets, accelerating the pace of developing effective treatments for TBI-related hippocampal impairment.
MiRNA-1976 Regulates the Apoptosis of Dopaminergic Neurons by Targeting the PINK1 Gene
Authors: Qiu Feng , Wu Yue , Xie Guojin , Cao Hui , Du Mingyang , Jiang Haibo
Published: February 2023

Introduction: Parkinson’s disease (PD), which is a neurodegenerative disease, requires urgently needed biomarkers to explore its mechanism. We screened for differences in the expression of microRNAs (miRNAs) and identified miR-1976 as a possible biomarker. Methods: Twenty-three patients and 30 controls were included in this study. Dopaminergic neurons from C57/BL mice were cultured. The miRNA expression profiles were analyzed using an miRNA microarray. MiR-1976 was identified as an miRNA that was differentially expressed between PD patients and age-matched controls. Lentiviral vectors were constructed, then apoptosis in dopaminergic neurons was analyzed using MTS (multicellular tumor spheroids) and flow cytometry. Transfection of miR-1976 mimics into MES23.5 cells was performed, and target genes and biological effects were analyzed. Results: Overexpression of miR-1976 increased apoptosis and mitochondrial damage in dopaminergic neurons. PINK1 (PINK1-induced kinase 1) was the most common target protein of miR-1976, and silencing of PINK1 caused mitochondrial damage and increased apoptosis of MES23.5 cells. Conclusions: MiR-1976 is a newly discovered miRNA that exhibits a high degree of differential expression with respect to the apoptosis of dopaminergic neurons. Given these results, increased expression of miR-1976 may increase the risk of PD by targeting PINK1 and may therefore be a useful biomarker for PD.
Select Congenital Heart Disease: Important Echocardiographic Features and Changes during Pregnancy
Authors: Majdalany David S. , Marcotte Francois
Published: February 2023

Congenital heart disease (CHD), which affects 1% to 2% of all births, is the most common abnormality in women contemplating pregnancy in western countries. With diagnostic and interventional advances, most patients with CHD survive into adulthood and require lifelong cardiac follow-up with cardiac imaging, particularly echocardiography and cardiac computed tomography. Multiple hemodynamic and physiologic changes of pregnancy may predispose patients with CHD to clinical decompensation and an inability to tolerate pregnancy. This manuscript reviews common CHD lesions, their repair or palliative interventions, long-term sequelae, important features to assess on cardiac imaging, and the impact of pregnancy on these types of lesions. Moreover, the review bridges the fields of CHD, cardiac imaging, and maternal cardiology, which will aid clinicians in counseling patients and managing pregnancies.
ЗМІСТ ТА ОСОБЛИВОСТІ ВИКОРИСТАННЯ ЕЛЕКТРОННОГО ПОСІБНИКА «БІОЛОГІЧНА ФІЗИКА» В УМОВАХ МЕДИЧНИХ ЗАКЛАДІВ ВИЩОЇ ОСВІТИ
Authors: Макаренко Олександр , Макаренко Катерина , Макаренко Володимир , Сілкова Олена , Матяш Людмила
Published: February 2023

Формулювання проблеми. Актуальною проблемою для сучасної вищої школи є розроблення та використання в навчальному процесі цифрових інструментів, які можна використовувати для забезпечення аудиторної, самостійної та дистанційної форм навчання. Метою дослідження є розкриття змісту та умов функціонування електронного навчального посібника «Біологічна фізика» під час вивчення медичної і біологічної фізики майбутніми лікарями в медичних ЗВО.
Матеріали і методи. З метою з’ясування стану розробленості проблеми дослідження в педагогічній теорії та практиці використано: теоретичний аналіз, порівняння, узагальнення і систематизацію. Для досягнення мети застосовано: анкетування майбутніх лікарів з метою визначення типу сприйняття інформації; педагогічне спостереження за їх роботою з електронним посібником; експертне оцінювання з метою виявлення форм, що активізують функціонування електронного посібника. Результати анкетування оброблено статистичними методами.
Результати. Авторами проаналізовано зміст та умови функціонування електронного навчального посібника «Біологічна фізика». В структурі кожної з його тем виділено теоретичну і практичну частини та засоби для самоконтролю. Цю структуру розглянуто на прикладі вивчення однієї з тем. Показано реалізацію переходів до різних видів діяльності. Розкрито компетентнісний підхід до навчання. Виділено умови функціонування електронного посібника в навчанні майбутніх лікарів, серед яких: врахування типів сприйняття інформації майбутніми лікарями; створення специфічного освітнього середовища в центрі якого є комп’ютер; гармонійне поєднання електронного посібника з іншими засобами навчання; врахування його особливостей при виборі форм і методів навчання; врахування специфіки дистанційного навчання при його використанні.
Висновки. Аналіз досвіду науковців, методистів та власного дослідження виділених умов функціонування електронного навчального посібника «Біологічна фізика», можна зробити висновок, що його використання активізує роботу студентів. Подальшого дослідження потребує серія електронних посібників з використанням задач і вправ медико-біологічного змісту.
КОНЦЕПЦІЯ ПІДГОТОВКИ МАЙБУТНІХ УЧИТЕЛІВ МАТЕМАТИКИ ТА ІНФОРМАТИКИ ДО ВИКОРИСТАННЯ ЗАСОБІВ ВІРТУАЛЬНОЇ НАОЧНОСТІ У ПРОФЕСІЙНІЙ ДІЯЛЬНОСТІ
Authors: Мулеса Павло
Published: February 2023

Постановка проблеми. У статті розкривається концепція професійної підготовки майбутніх учителів математики та інформатики до використання засобів віртуальної наочності у професійній діяльності,

Матеріали і методи. Основою дослідження стали наявні дослідження підготовки вчителів математики та інформатики, зміна психологічного сприйняття молоддю інформації (візуальний контент) та наявні практики їх навчання. Використано теоретичні методи наукового пізнання: аналіз результатів теоретичних досліджень, узагальнення практик підготовки молоді, контент-аналіз інтернет-ресурсів.

Результати. провідними ідеями концепції стали: визнання цінності для суспільства професійної підготовки майбутніх учителів математики та інформатики до використання засобів віртуальної наочності у професійній діяльності; формування готовності майбутніх учителів математики та інформатики до використання засобів віртуальної наочності у професійній діяльності у відповідності до розвитку освітньої галузі та цифрових технологій, а також з урахуванням особливостей сприйняття молоддю візуального контенту; модернізація процесу професійної підготовки вчителів з акцентом на візуальні технології, матеріали і засоби в інформаційно-освітньому середовищі ЗВО; набуття в процесі професійної підготовки первинного досвіду використання засобів віртуальної наочності в освітньому процесі; врахування тенденцій трансформації професійної освіти у напрямку підвищення професіоналізму майбутніх вчителів математики та інформатики, гуманізації та гуманітаризації вищої освіти, створення інформаційно-цифрового середовища закладу освіти; забезпечення особистісного професійного розвитку, саморозвитку та самовдосконалення вчителів математики та інформатики упродовж життя, формує їх позитивну мотивацію та здатність досягти високого рівня готовності майбутніх учителів математики та інформатики до використання засобів віртуальної наочності у професійній діяльності; впровадження нових форм організації освітнього процесу, зокрема, у застосуванні інноваційних освітніх, які забезпечують ефективність навчально-методичного та організаційного супроводу; креативна і творча діяльність викладачів закладів вищої освіти, яка спрямовується на розширення суб’єктних функцій майбутніх учителів математики та інформатики для формування в них умінь генерувати нові знання і технології, розробляти інноваційний професійно-педагогічний продукт (послуги, методики тощо), творчо підходити до власної педагогічної діяльності. Концепція підготовки розкривається за методологічному, теоретичному і практичному рівнях.

Висновки. Розроблена концепція може стати основою проєктування педагогічної системи підготовки майбутніх учителів математики та інформатики до застосування віртуальної наочності у професійній діяльності.
ВПЛИВ ЗАСОБІВ ТРЕНУВАЛЬНОЇ СИСТЕМИ «КРОСФІТ» НА ФІЗИЧНУ ПІДГОТОВЛЕНІСТЬ ТА ФІЗИЧНИЙ РОЗВИТОК СТУДЕНТІВ
Authors: Балашов Дмитро , Стасенко Олексій
Published: February 2023

В статті розглянуто вплив засобів тренувальної системи «кросфіт» на фізичну підготовленість та фізичний розвиток студентів 18-21 років. Було розроблено методику розвитку силових якостей з використанням системи кросфіт. У ході підготовки статті були використані такі методи дослідження: теоретичні (аналіз науково-методичної літератури з проблеми дослідження); емпіричні (педагогічне тестування); педагогічний експеримент; методи математичної статистики (оброблення і порівняння результатів кількісного та якісного аналізу одержаних результатів). У процесі педагогічного дослідження нами було розроблено і впроваджено в процес фізичного виховання юнаків студентського віку експериментальної групи методику розвитку силових якостей з використанням засобів тренувальної системи «кросфіт». До змісту основної частини заняття в експериментальній групі було впроваджено силовий блок (підтягування, згинання-розгинання рук в упорі лежачі, вправи для м’язів живота, різні варіанти стрибкових вправ, вправи з обтяженням, «човниковий біг», «бурпі»), який був розрахований на 3 місяці і містив 5−6 комплексів вправ в раунді. На кожному окремому занятті необхідно було виконати 5 раундів. Для уникнення адаптації до навантаження, силовий блок щомісяця коригувався, а саме: зміст вправ та їх дозування. Одночасно із впровадженням силових вправ комплекси містили швидкісні і швидкісно-силові вправи, а також для вправи розвитку витривалості. Особливістю впровадженого комплексу було застосування вправ на гнучкість динамічного та статичного стретчингу для уникнення закріпачення в суглобах і м’язах. Проведення дослідження із застосуванням педагогічних тестів визначило ефективність розробленої та впровадженої нами методики розвитку силових якостей з використанням засобів тренувальної системи «кросфіт» для студентів 18–21 років.
Machine learning-based lung cancer diagnosis
Authors: DİRİK Mahmut
Published: February 2023

Cancer is one of the leading health problems, occurring in various organs and tissues of the body, and its incidence is increasing worldwide. Lung cancer is one of the deadliest types of cancer. Due to its worldwide prevalence, increasing number of cases, and deadly consequences, early detection of lung cancer, as with all other cancers, greatly increases the chances of survival. As with all other diseases, the diagnosis of cancer is only possible after the appearance of various symptoms and an examination by specialists. Known symptoms of lung cancer are shortness of breath, coughing, wheezing, jaundice in the fingers, chest pain, and difficulty swallowing. The diagnosis is made by an expert on site based on these symptoms and additional tests. The aim of this study is to detect the disease at an earlier stage based on the symptoms present, to assess more cases with less time and cost, and to achieve results in new situations that are as successful or even faster than those of human experts by deriving them from existing data using different algorithms. The aim is to develop an automated model that can detect early-stage lung cancer based on machine learning methods. The developed model includes nine different machine learning algorithms (NB, LR, DT, RF, GB, and SVM). The success of the classification algorithms used was evaluated using the metrics of accuracy, sensitivity, and precision calculated using the parameters of the confusion matrix. The results obtained show that the proposed model can detect cancer with a maximum accuracy of 91%.
First-Principles Models for van der Waals Interactions in Molecules and Materials: Concepts, Theory, and Applications
Authors: Vishwanath Manish
Published: February 2023

Noncovalent van der Waals (vdW) or dispersion forces are ubiquitous in nature and influence the structure,stability, dynamics, and function of molecules and materials throughout chemistry, biology, physics, and materials science.These forces are quantum mechanical in origin and arise from electrostatic interactions between fluctuations in theelectronic charge density. Here, we explore the conceptual and mathematical ingredients required for an exact treatmentof vdW interactions, and present a systematic and unified framework for classifying the current first-principles vdWmethods based on the adiabatic-connection fluctuation−dissipation (ACFD) theorem (namely the Rutgers−ChalmersvdWDF, Vydrov−Van Voorhis (VV), exchange-hole dipole moment (XDM), Tkatchenko−Scheffler (TS), many-bodydispersion (MBD), and random-phase approximation (RPA) approaches). Particular attention is paid to the intriguingnature of many-body vdW interactions, whose fundamental relevance has recently been highlighted in several landmarkexperiments. The performance of these models in predicting binding energetics as well as structural, electronic, andthermodynamic properties is connected with the theoretical concepts and provides a numerical summary of the state-oftheart in the field. We conclude with a roadmap of the conceptual, methodological, practical, and numerical challenges thatremain in obtaining a universally applicable and truly predictive vdW method for realistic molecular systems andmaterials.
Secondary Electron Emission from Space Materials: Estimating Total Secondary Electron Yield from Surface Potential Measurements
Authors: Vishwanath Manish
Published: February 2023

—Secondary electron emission (SEE) is a key componentin determining spacecraft potential. It is also significant in theactivation of the multipactor phenomena in waveguides (electronavalanche in microwave electric fields). In this study, we offer anovel approach for measuring low-energy SEE on dielectrics andconductors (incident electron energy below 20 eV). It is based onsurface potential measurements taken with a Kelvin probe (KP)following electron irradiation. It is best suited to insulating materials,although it may also be utilised on metals by allowing the samplepotential to float. We report the findings of SEE tests on metals usedin waveguides, as well as Kapton, Teflon, and CMX cover glass. Thedistance between the electron gun and the sample is selected to beminimal in comparison to the Larmor radius in order to eliminate anyexperimental artefacts caused by the earth magnetic field and toconduct accurate low-energy experiments with the KP technique
Ground plane impact on quadrifilar helix antenna performance with respect to deployment heights
Authors: Vishwanath Manish
Published: February 2023

The quadrifilar helix antenna (QHA) is used in satellite communications. Theperformance optimization of QHA input and radiation characteristics in the presenceof infinite and finite metallic ground planes is presented in this study. It has beendiscovered that for the infinite ground plane, input characteristics such as impedanceand voltage standing wave ratio (VSWR) are stable, and the antenna has a widerhalf power beamwidth (HPBW). Smaller metallic platforms that serve as finiteground planes result in higher 3dB axial ratio beamwidth and boresight axial ratio.The use of QHA on smaller metallic platforms, such as nanosatellites and CubeSats,enhances its circularly polarised beamwidth and boresight axial ratio. On large lowearth orbit (LEO) satellites, however, steady input characteristics and a widerHPBW have been achieved at the expense of a small circularly polarised beamwidthand a decreased boresight axial ratio
Technology Synchronization: What Does the Future Look like with Machine and Deep Learning
Authors: Vishwanath Manish
Published: February 2023

The area of machine learning is entering a golden age, with deep learning gradually taking the lead. To develop computer models, deep learning employs numerous layers to represent data abstractions. Deep learning methods like generative adversarial networks, convolutional neural networks, and model transfers have totally transformed our understanding of information processing. However, there is a gap in knowledge behind this extremely fast-paced domain since it has never been portrayed from a multiscale perspective before. Because of a lack of fundamental knowledge, these strong approaches are reduced to black-box devices that stifle progress on a fundamental level. Furthermore, deep learning has been portrayed as a panacea for all machine learning stumbling obstacles, which is far from the case. This article provides an in-depth study of pivotal and revolutionary developments in deep learning applications, as well as a complete overview of historical and contemporary state-of-the-art methodologies in visual, audio, and text processing; social network analysis; and natural language processing. It was also attempted to evaluate the problems encountered in deep learning, such as unsupervised learning, black-box models, and online learning, and to demonstrate how these difficulties might be turned into fruitful future research directions.
Secondary electron yield decrease of laser drilled microporous gold surfaces: empirical modelling and Monte Carlo simulation
Authors: Vishwanath Manish
Published: February 2023

This study looks at reducing secondary electron yield (SEY) from a metal surface using a microporous array created using the laser drillingprocess. For normal and oblique primary electron incidences, we present a generic empirical model to match the empirically determined SEYof a flat gold surface. We build a two-dimensional Monte Carlo (MC) simulation technique based on this empirical model to evaluate theeffective SEY of a microporous array. It is discovered that the SEY from a porous surface is much lower than that from a flat surface. Our MCresults are found to be in extremely excellent agreement with the experimental data after accounting for all generations of secondary electronsinside a well. The SEY's reliance on the aspect ratio of the micropores and the porosity of the surface is investigated. For pores with arbitraryaspect ratios, a simple empirical method has been presented to calculate the effective SEY of the gold microporous array.
Power Generation Footstep*
Authors: Hafeez Farrukh
Published: February 2023

This paper is all about generating electricity when people walk on the Floor. Think about the forces you exert which is wasted when a person walks. The idea is to convert the weight energy to electrical energy The Power Generating floor intends to trans- late the kinetic energy to the electrical power. Energy Crisis is the main issue of world these days. The motto of this research work is to face this crisis somehow. Though it won’t meet the requirement of electricity but as a matter of fact if we are able to design a power generating floor that can produce 100W on just 12 steps, then for 120 steps we can produce 1000 Wattand if weinstall such type of 100 floors with this system then it can produce 1MegaWatt. Which itself is an achievement to make it significant
Ground Plane Influence on Quadrifilar Helix Antenna Input Impedance
Authors: Vishwanath Manish
Published: February 2023

The fluctuation in the input impedance of a QuadrifilarHelix Antenna (QHA) vs the height of a perfect conducting groundplane (PEC) is examined in this study. The findings reveal thatwhen the height of the ground plane changes from 0.05 to 1.0, theactual component of the input impedance varies the most (44 to 50in simulations and 41 to 52 in measurements). The change in theactual component of QHA input impedance from 0.3 to 1.0 issmall (varies between 48 and 50.6 in simulations and 48 to 52 inmeasurements). The imaginary component of input impedance, onthe other hand, varies between -10 and 0 in simulations and 7 and0 in measurements and is inconsequential at the height of 0.3(varies between -2.0 and 0.2 in simulations and 3 to 0 inmeasurements). The fairly consistent input impedance of QHAwith regard to ground plane height was examined further withhorizontal dipole and rectangular loop with varied orientations.Variations in input impedance (real and imaginary component) aregreatest for horizontal dipole (HD) and horizontal andperpendicular loops as height goes from 0.05 to 1.0. (H&PL). Thedifferences are minor for the other two orient
Homofobia y discriminación por orientación sexual: perfume autentico de la cultura en Latinoamérica
Authors: Rossel Ysaelen Josefina Odor
Published: February 2023

El mundo actual está construido sobre una utopía de libertad ilimitada, donde todos pueden estar satisfechossometiéndose a sus propias inclinaciones turbulentas, desafiando la ley de Dios y las leyes de la naturaleza,como, en otras palabras, San Pablo, cada persona ha impreso en él su alma. La discriminación basada en ladiferencia en las tendencias sexuales es una constante en grupos y perfumes derivados del autoritarismo enLatinoamérica. El abordaje sobre lo que pensamos hoy es el deber ser de la sexualidad, llevó a la interrogante,¿Es la expresión social de la homofobia un patrón cultural de autenticidad cultural en Latinoamérica?; de laliteratura, la mitomanía masculina emergió como sistemas de roles que definen los comportamientos esperados para cada género y describen connotaciones negativas y situaciones opuestas en diversas formas. Basada en estructuras sociales de los estados, familias y religión, sigue siendo un discurso no ortodoxo, vigente en la actualidad, siendo estas las bases fundamentales del perfume auténtico latinoamericano sobre la homofobia yla discriminación.
Effects of concentrated and intense heavy rain on phreatic eruptions ～Based on a case study of the phreatic eruptions of Mt. Ontake in Japan-～
Authors: Uchida Nobuo
Published: February 2023

"This paper is a non-peer reviewed preprint submitted to EarthArXiv"For humans living in an economic zone adjacent to volcanoes, the reality of unpredictable eruptions is a constant concern. This paper presents a new view on the phreatic eruption process of Mt. Ontake, Japan. The purpose of this posting is to find ways to reduce casualties from phreatic eruptions. As a background, there is the current situation that phreatic eruptions where magma does not move cannot be predicted. By analyzing the process of phreatic eruptions in which the magma does not move, future eruption prediction measures will be established. The significance of the submission is that this research is shared not only by researchers in Japan but also by researchers around the world. It is highly likely that the water necessary for the phreatic eruption was supplied by accidental heavy rains in addition to the water stored in the mountain. On the other hand, it is presumed that the lava rock surrounding the magma cooled from the outside over a long period of time. As the cooling water from heavy rain hit the heated lava rocks continuously, the lava rocks were gradually scraped away while the vaporization phenomenon continued, colliding with the hotter lava rocks and leading to a large explosion. At this time, the power of the explosion was not able to pass through the escape route, and it became a large eruption that reached the top of the mountain. The event occurred 7 minutes after it was first observed by the seismometer. As a result, it was not possible to predict the eruption, resulting in casualties.
Trainer Perspectives on Personality-Based Group Training: Learning Objectives, Training Outcomes, and Best Practice Recommendations
Authors: Osborn Seth , Brummel Bradley J. , Walton Hayley
Published: February 2023

Despite the prevalence of personality-based group training in applied settings, little systematic research has examined the outcomes of such interventions. Even less research has explored the specific components of such interventions that might contribute to or detract from group processes and performance. To organize and spur this line of inquiry, we reviewed the literature on learning objectives, training outcomes, and best practice recommendations for personality-based training. We also interviewed 26 trainers who use personality assessments, such as the Myers-Briggs Type Indicator, DISC, CliftonStrengths, and Hogan Personality Inventory, concerning these topics. We organized their responses to each topic into categories, using thematic content analyses for the learning objectives and training recommendations. Common learning objectives involve increasing self- and other-awareness, preference for personality diversity, interpersonal skill, and individual- and unit-level attitudes and performance. Anecdotal reports generally suggest personality-based training can improve self-awareness and interpersonal skill, but some reports describe risk of stigmatization and subgroup conflict. Differing approaches to these trainings appear to vary in their effectiveness. Common best practice recommendations from trainers include describing personality flexibly, emphasizing the value of personality diversity, tailoring the training content based on group personality profiles, ensuring trainees understand that personality testing is for developmental purposes, and treating personality feedback as confidential. We conclude by summarizing existing guidance for practitioners and suggesting two future research streams: (1) controlled evaluation of training outcomes and (2) exploration of the proposed mechanisms of action in personality-based training.
Six Month Admissions History of Intentional Self-Harm Patients: Evidence for Latent Imminent Risk
Authors: Pallas John
Published: February 2023

Background: The burden of hospital admissions for intentional self-harm (ISH) is not limited to the admission for ISH itself. Patients admitted for ISH have a history of admissions for mental disorders without ISH. In addition, prior research indicates suicidal ideation is predictive of intentional self-harm. However, as much as 50% of suicidal ideation remains undisclosed in the medical setting. Objective: Describe hospital admissions associated with ISH, including typical mental health treatments provided and patterns of hospital admissions prior to the first ISH visit in 2019. Identify differences between those admitted prior to the ISH admission with and without suicidal ideation. Method: Retrospective study of all mental disorder related inpatient admissions in the Healthcare Cost and Utilization Project's 2019 National Readmissions Database for patients with at least one admission for ISH in the second half of 2019. For patients admitted in July 2019 and later, mean durations between the first admission for ISH and the index admission in the prior 6 months for patients: with a primary mental disorder without any admissions for suicidal ideation (Group A); and with suicidal ideation (Group B) were computed. Results: A weighted population of 2,997 inpatients was derived (Group A: 1,212; Group B: 1,785). The mean duration between index admission and the first admission for ISH was 78 days in Group A and 83 days in Group B. The difference in group means of 5 days was statistically significant. Conclusion: For a patient that will be subsequently admitted for ISH, the disclosure of suicidal ideation in a hospital visit for a mental disorder within the prior 6 months is not predictive of the immanence of ISH risk.
Affective integration: episodic mechanisms underlying preconditioned threat responses
Authors: de Vries Olivier , Kindt Merel , van Ast Vanessa Anna
Published: February 2023

Whereas many studies have investigated generalization of learned threat across semantic dimensions, little attention has been given to the possibility that Pavlovian threat responses may spread beyond what is directly learned through episodic associations. Here, we increased the demand on episodic memory in a sensory preconditioning task to assess whether and how episodic memory contributes to threat generalization. Participants encoded forty unique episodes, each consisting of two neutral stimuli, after which one of each pair was newly associated with either an aversive or a neutral stimulus on the following day. Another day later, both stimuli of the original memories were found to trigger enhanced pupil dilation if one was indirectly linked with an aversive stimulus. This effect was independent of whether the declarative associations encoded on day one were accurately retained on the day of testing, and confined to trials on which the indirectly associated stimulus was consciously brought to mind, suggesting an important role for relational memory processes. There was no moderating effect of trait-anxiety. The present study demonstrates that the human defensive system is remarkably adept at quickly anticipating threat based on information acquired over separate events, and gives a first glimpse into how this ability is facilitated by episodic memory.
Profiles of Acculturation and Cultural Stress Among Hispanic/Latinx College-Attending Emerging Adults
Authors: Meca Alan , Cruz Bethany , Lucero Jacqueline , Ward Colleen , Schwartz Seth J. , Stuart Jaimee , Szabo Agnes , Hinojosa Zenetta , Laird Angie
Published: February 2023

Objective: The current study identified unique profiles of cultural stressors (i.e., bicultural stress discrimination, and negative context of reception) and acculturative strategies (i.e., heritage practices, heritage identification, U.S. practices, and U.S. identification), in Hispanic/Latinx (HL) emerging adults. Additionally, we examined associations between positive and negative psychosocial functioning, with profiles of cultural stressors and acculturation. Method: The current study utilized baseline data drawn from a daily diary study on acculturation collected at a large public Hispanic Serving Institution. The sample for this study consisted of 779 HL college students (75.8% female, Mage=20.80 years, SD=2.66). Results: Latent Profile Analysis identified four distinct profiles. The Bicultural and Low Cultural Stressors (B-LowCS; 53.55%) was marked by heritage and U.S. cultural orientation and low levels across all cultural stressors. The Marginalization and High Acculturative Stressors (M-HighAS; 20.13%) was marked by low heritage and U.S. cultural orientation, high acculturative stressors, and low discrimination. The third profile, the Heritage Rejection and Low Cultural Stressors (HR-LowCS; 16.05%) was marked by rejection of heritage culture and low cultural stressors. Finally, the Separation and High Cultural Stressors (S-HighCS; 10.26%) was marked by low U.S. cultural orientation and high cultural stressors. Consistent with passed research, the B-LowCS profile was marked by the highest level of psychosocial functioning, and the lowest levels of internalizing and externalizing symptoms. Conclusions: The results of the current study highlight the need to further our understanding configurations of cultural stressors and acculturation, and the implications of these distinct profiles on psychosocial functioning in HL emerging adults.
How to prepare a rebuttal letter: Some advice from a scientist, reviewer and editor
Authors: Palminteri Stefano
Published: February 2023

The goal of the present piece is to provide some experience-based advice on how to write an optimal (or effective) rebuttal letter. After many years as a reviewer and some years as an editor, I realized that great diversity exists in the way rebuttal letters are organized, but also that not all formats are equally effective. This is why I thought that the community at large could benefit from sharing my thoughts.
Common content, philosophy, and programming support thriving collaborations between cognitive science labs and museums
Authors: Dillon Moira Rose , Lawrence Cindy
Published: February 2023

University research labs focusing on education, psychology, and cognitive development have been collaborating with museums more and more over the past decade. Nevertheless, cognitive science labs that primarily engage in basic as opposed to applied research may find it difficult to entice museums to collaborate, and existing collaborations may fall short of their full potential to garner benefits to labs and museums alike. Here we focus on a kind of lab and museum collaboration that has common content, philosophy, and programming and impacts both scientific theory development and museum practice. By illustrating one example of a collaboration between the Lab for the Developing Mind at New York University and the National Museum of Mathematics in New York City, we offer practical tips and suggestions for other cognitive science labs aiming to achieve strong lab-museum synergy.
Efficient scale and scope of business models used in municipal solid waste management
Authors: Di Foggia Giacomo , Beccarello Massimo
Published: February 2023

The paper compares the efficiency of alternative municipal solid waste management business models: a single provider against multiple providers. The drivers of municipal solid waste management costs are analysed to test the impact of the scale and scope of municipal solid waste management services on the average cost. While the business-as-usual scenario foresees a single provider, the alternative scenario foresees multiple providers. Based on the empirical data on municipal waste management costs, on average, the size and the average cost of the service are inversely related. This trend is supported using subsets defined by the quantity of waste managed. Multiple factors aid in explaining this result, and among others, due to scale and scope, factors such as transition costs increase with the number of players running different services. The provision of public services of economic interest should favour the participation of more companies wherever possible to the extent that social surplus is produced. However, pursuing this principle to the detriment of efficient service delivery is not ideal. This paper demonstrated that a single-provider waste management business model is efficient under specific conditions, as in this article. This paper presents an original research methodology for comparatively analysing waste management service efficiency in urban areas and provides adequate evidence using alternative measures of costs according to the phase of the waste management chain, the scale, and ultimately the scope of municipal solid waste management services.
The Religious Right and Russia: Christian Nationalism and Americans' Views on Russia and Vladimir Putin Before and After the Ukranian Invasion
Authors: Perry Samuel , Riccardi-Swartz Sarah , Davis Joshua , Grubbs Joshua B.
Published: February 2023

Since 2016, Americans’ attitudes toward Russia and Vladimir Putin have shifted, with Republicans becoming far more supportive of both. And though condemnation of Russia’s invasion of Ukraine in 2022 remains bipartisan, many Christian-right leaders still support Putin and Russia. What undergirds this support? Drawing on three national data sets, we theorize Americans’ warmth toward Putin and Russia is reinforced by an ideology that seeks to institutionalize America’s mythical Anglo Protestant ethno-culture—Christian nationalism. Though we propose Christian nationalism’s relationship with Russia is more contingent on Russia’s geopolitical activity vis-à-vis the US, we theorize Christian nationalism consistently predicts Putin support due to his authoritarian ethno-nationalism. April 2018 data show those who affirm America’s Christian heritage in the past and/or present are more likely to view Putin and Russia favorably and Russia as our ally. March 2021 data also reveal a linear positive association between Christian nationalism and favorability toward Putin. And March 2022 data reveal a linear positive association between Christian nationalism and admiring Putin’s leadership. They also show a U-shaped curvilinear relationship with viewing Russia as a threat. Paradoxically, Christian nationalism may warm Americans toward foreign authoritarians like Putin even when it compels Americans to perceive their nations as threats.
Adult Emergence and Morphometrics of Chinese Citrus Fly, Bactrocera minax (Enderlein) (Diptera: Tephritidae) in Nepal
Authors: Regmi Bhawana , Tiwari Sundar , Srivastava Arvind , Lamsal Hom Nath , Pandit Januka , Shrestha Shruti , Pandit Shailesh , Adhikari Debraj
Published: February 2023

Chinese citrus fly, Bactrocera minax is a destructive and univoltine pest of citrus fruits. Geographical altitudinal gradients as well as prevailing climate affect the biology and ecology of insect. Hence, this study aimed to ascertain the effect of altitude on the adult emergence and morphological variations in various ecological settings of Ramechhap district of Nepal from February to June 2021 in citrus orchard. Six altitude ranges were selected in 50 m distance from 1200 to 1500 m above sea level (masl), ranging from 1201-1250 masl, 1251-1300 masl, 1301-1350 masl, 1351-1400 masl, 1401-1450 masl and 1451-1500 masl. The peak adult emergence periods were the 2nd, 3rd, 4th week of April in 1201-1250 masl, 1251-1300 masl, 1301-1350 masl, respectively, followed by 1st, 2nd and 3rd week of May in 1351-1400 masl, 1401-1450 masl, 1451-1500 masl, respectively. Morphometrics of Chinese citrus fly such as weight, length and width of pupa and adult were almost similar to the species collected in various altitudes. The average body length of male Chinese citrus fly adult was 11.58± 0.112 mm while female was 15.57± 0.076 mm. The average wingspan of male was 20.71± 0.285 mm while that of female was 23.14± 0.156 mm. The longevity of adult Chinese citrus fly species increased with increase in altitude. This information could be useful to design an appropriate management plan of Chinese citrus fly in various altitudinal gradients of Nepal.
Accidental Migration of a Guide Wire During Haemodialysis Catheter Insertion Through Right Internal Jugular Vein
Authors: Keyal Niraj Kumar , Sah Manbodh Kumar , Deo Ujjwal , Chaurasia Rupesh
Published: February 2023

Introduction: Intensivist and Nephrologist generally place the dialysis catheter to obtain vascular access for immediate and short-term haemodialysis. We hereby present a case of a 54 years male with a past history of diabetes mellitus, hypertension, and chronic kidney disease stage four who was planned for immediate haemodialysis for severe hyperkalaemia and metabolic acidosis. A haemodialysis catheter was inserted under ultrasound guidance through the right internal jugular vein, but during the procedure, the guidewire was pushed into vein. The chest X-ray showed the looping of the tip of a guidewire. It was successfully surgically extracted, haemodialysis was done through the right femoral vein successfully, and the patient was discharged. From this, we want to emphasize that accidental migration is a fatal, avoidable, preventable complication. Simple measures like holding the guidewire until removal from vessels, vigilant supervision of the trainees, avoidance of vigorous force during insertion of guidewire may prevent this complication.
Collocation Analysis in Twelve Grade English Textbook
Authors: Yunianti Sofi , Fatin Idhoofiyatul , Wiajaya Sulton Dedi
Published: February 2023

Learning foreign language needs several ways. One of the ways is collocation. Collocation is considerably prominent in learning foreign language due to the influence in language comprehension. The high proficiency in collocation reflects high proficiency in foreign language comprehension. It is therefore this study aims to scrutinize the collocation which used in twelve grade English Textbook. this study applied corpus software, namely antconc. the first step for collecting the data, was changing the data from pdf to txt and process it in antcont for finding the top twenty wordlist. Then, find the top twenty sentences based on the lexical which find from wordlist. Based on the antcont process, the finding illustrates that only two types of collocation which occurred in twelve grade English textbook. It can be reflected that twelve grade English textbook limited provided collocation. Although, it is very crucial as learning material plays significant role in teaching learning process. As a result, this study is estimated to gain insight about in teaching English as foreign language, especially teaching media in textbook.
The Effectiveness of Digital Story Telling in EFL Classroom
Authors: Budianto Richo Hermawan , Syahruzah Juang Kurniawan
Published: February 2023

The research aims to find out the effectiveness of Digital Story Telling media in listening class students at University of PGRI Yogyakarta. This research was experimental research which used quasi experimental method. Therefore, the data were collected by observation, interview, test, and questionnaire. Samples of this research were 28 students of 10 male and 18 female in the second semester English department students. The samples were divided into two groups, there were experiment group and control group. Both of groups were given pretest before treatment and posttest after treatment. Students in experiment group got treatment to study English listening by Digital Story Telling. The result of the research shows that Digital Story Telling is effective to improve listening skill. Result of the hypothesis measured from the post-test of the experiment class. The result shows the value of significance t-test is 0.000 which is lower than 0.05. It means that Ha is accepted and H0 is rejected. Mean of control group in pre-test is 34.28, thus in experiment group is 37.85. Mean of control group in post-test is 39.28, while in experiment group 47.14. It concludes that Digital Story Telling as media is effective to improve student in learning listening at second-semester student in English Language Education Study Program at the University of PGRI Yogyakarta.
Psycholinguistic Study on Expressive Language Disorder of Autistic Characters in Miracle Run Movie
Authors: Fitriatul Masitoh  , Rohana Yogi
Published: February 2023

Recently, it has been reported that the prevalence of autism has increased significantly. One of the characteristics of autism is a language problem, or it is well-known linguistically as a language disorder. This study is conducted to analyze categories of expressive language disorder of autism represented in Miracle Run Movie and contexts affecting them in producing those utterances. This study applies a descriptive qualitative approach using Carroll's framework (1985). As the result of analysis on 75 data, Philip and Steven, as the autistic characters, face all kinds of expressive language disorders covering phonology, syntax, semantics, and pragmatics in various cases. They face phonological language disorder in the case of inappropriate stress, flat and singsong intonation, and expressionless speech. They also face syntactical language disorder in the case of echolalia and semantic language disorder involving their disability in using semantic bias. In addition, they have pragmatic language disorder in the case of fewer complex gestures, politeness strategy, spontaneous remarks, misuse of pronouns, limited repertoire devices to initiate a topic in a conversation, and tendency to use a question to gain a response from a listener. Concerning the context when the autistic characters produce expressive language disorder, there are six types of context affecting their utterances. They have expressive language disorder when they are posing a question to someone, answering a question of others, expressing their ambition, expectation, surprise, and something they dislike. This study is an excellent guide for EFL teachers interested in working with autistic students.
Analysis of the Mechanism of the Common Organization of the Markets for Agricultural Products in the European Union
Authors: Zagorova Krassimira
Published: February 2023

The Common Organization of the Market for Agricultural Prod­ucts in the European Union is part of the common agricultural policy, which ensures both stable and predictable markets and resilient purchase prices, which in turn safeguards farmers’ stable earnings and provides constant supply of quality food to consumers. The aim of this study is to analyze the applicability and adaptability of the mechanism of the common organization of markets in the EU, including: its internal aspect, mainly related to interventions in the market for agricultur­al products, and its external aspect related to the trade with third countries, import and export licenses, refund of part of costs associated with exporting agricultural products produced in the Community, etc. The Common Organization of Markets, as a basis for implementing the EU Common Agricultural Policy, operates within a financial framework period­ically updated by the European Commission in order to adequately imple­ment the principle of subsidiarity, allowing EU Member States to play a key role in terms of interventions in the agricultural sector.
Corporate Social Responsibility in the Albanian Banking System
Authors: Dragusha Blerta , Lugji Jasmina
Published: February 2023

Corporate social responsibility is a new concept in Eastern Eu­rope and particularly in Albania. Albania came out of the communist re­gime without any kind of heritage or experience in the field of conception and later in that of applying social policies. But after the ’90-s, the opening of Albania to free trade brought dramatic changes. These changes had their essential influences and on the field of social policies. The paper will make a presentation of the actual level of corporate social responsibility undertaken by each bank operating in Albania. The authors have built some graphs according to the number of initiatives in achieving each of the targets for each Albanian bank by analyzing and addressing the following in more detail each bank. The paper will be closed with some con­clusions and recommendations.