bluuebunny/crossref_metadata_2025 huggingface dataset:
Generation and characterization of the VP1 recombinant protein of the chicken anemia virus
Authors: Грудинин Михаил , Grudinin Mihail , Комиссаров Андрей , Komissarov Andrey , Гусейнова Алина , Guseynova Alina , Шалджян Арам , Shaldzhyan Aram , Забродская Яна , Zabrodskaya Yana , Жук Дарья , Zhuk Dar'ya , Алиев Алаутдин , Aliev Alautdin
Published: May 2019

The aim of this study is to obtain a VP1 recombinant protein of the chicken anemia virus, capable of specifically detecting antibodies in the blood sera of sick chickens. Materials and methods. Cloning of a fragment of the VP1 gene of an infectious anemia virus of chickens was performed in the expression plasmids pET15b and pGEX-3T in the context of reading the polyhistidine sequence and glutathione-S-transferase, respectively. The recombinant proteins 6HIS-ΔVP1 and GST-ΔVP1 expressed in E. coli Rosetta (DE3) strains were purified by metal affinity chromatography. Amino acid sequence of recombinant proteins was confirmed by mass spectrometry. The specificity of the interaction of recombinant proteins with polyclonal antibodies was determined by ELISA. The ability of the recombinant 6HIS-ΔVP1 protein to detect antibodies in field and blood sera of SPF chickens was evaluated by indirect ELISA. To control the specificity of the antigen, the immune sera of birds for viruses of infectious bronchitis, Newcastle disease, infectious laryngotracheitis, adenoviral infection, Mycoplasma gallisepticum, and negative serum of chickens were used. Results. The recombinant VP1 protein of chicken anemia virus containing a polyhistidine tag (6HIS-∆VP1) was obtained. It was shown that this recombinant protein is able to specifically detect antibodies in the blood sera of sick chickens. Conclusion. The obtained recombinant protein 6HIS-ΔVP1 can be used to detect antibodies to the chicken anemia virus in the serum of sick chickens, and can also be considered as a potential component of vaccines against this virus.
Arutyun Khristoforovich Sarkisov is the founder of home veterinary mycology and mycotoxicology (110th Anniversary)
Authors: Левитин Марк , Levitin Mark
Published: May 2019

A.Kh. Sarkisov entered the history of science as the founder of veterinary mycology and mycotoxicology. Outstanding talent of the scientist was harmoniously combined in A. Kh. Sarkisov with the talent of a true teacher. For outstanding contribution to the development of biological science, the introduction of scientific achievements in the production and training of scientific personnel. A.Kh. Sarkisov was awarded the title of Hero of Socialist Labor. A. Kh. Sarkisov's scientific activity is a bright milestone in the history of science of the 20th century.
PENGARUH BUDAYA ORGANISASI DAN KESELAMATAN KERJA TERHADAP KINERJA MELALUI KEPUASAN KERJA SEBAGAI VARIABEL INTERVENING
Authors: Suratman Andriyastuti , Supriyantiningsih Lilis
Published: May 2019

This study discusses about the influence of organizational culture andwork safety on performance with job satisfaction as an intervening variable in Vocational High School 1 Bawang. This is a quantitative research by using questioner as a tool to collect data. The data collection technique used census technique with questionnaire as instrument. This research supported by 103 respondens of 114 teachers totally in Vocational High School 1 Bawang. Data analysis using SPSS 23, including multiple linear regression analysis and path analysis with Sobel analysis.The result of the research are; there is an influence of organizational culture, work safety on the job satisfaction partially, there is an influence of organizational culture, work safety, and job satisfaction on the performance partially, and there is an influence of organizational culture and work safety on performance with job satisfaction as intervening variable. All coefficients are positive values that show a positive influence except the effect of safety on the performance that have negative coefficients numbers.
PENGARUH TEKANAN KETAATAN, GENDER, KOMPLEKSITAS TUGAS, INDEPENDENSI, DAN PENGALAMAN AUDITOR TERHADAP AUDIT JUDGMENT
Authors: Priyoga Irfan , Ayem Sri
Published: May 2019

This study analyzes the influence of pressure obedience, gender, task complexity, independence, and auditor experience on audit judgment. The population in this study were auditors who worked in the financial supervision agency and the construction of representatives of special regions of Yogyakarta. The type of data carried out in this study is primary data. The data in this study which will be analyzed using an analysis tool consisting of data quality test, descriptive statistics, classical assumption test, and hypothesis testing with the help of SPSS version 16.0 program. the results of this study partially (t test), namely the pressure variable obedience, gender, and independence does not affect audit judgment. While task complexity variables and auditor experience have a significant positive effect on audit judgment. For simultaneous results (f test) together affect audit judgment.
PENGARUH INFORMASI FUNDAMENTAL PADA NILAI INTRINSIK SAHAM DENGAN PENDEKATAN PRICE EARNING RATIO DI BURSA EFEK INDONESIA TAHUN 2011-2015
Authors: Anggraini Shinta , Tjahjono Achmad
Published: May 2019

Stocks are an interesting instrumen for investor to invesment. By making a purchase of stock, investor expect to get provit form capital gain and dividen although must get risk.In the stock investment process, investors do an evaluation and analysis of factors that can affect the intrinsic value of the company’s stockprice using one of the fundamental analysis method with Price Earning Ratio (PER) approach. The purpose of this study is to obtain empirical evidence of the influence of firm size, sales growth, dividen police and value of the rupiah exchange rate on intrinsic value of stock. The populationof this study banking companies listed on the Indonesian Stock Exchange period 2011-2015. This study uses secondary data taken from the annual report of banking companies during the year 2011-2015 listed on the Indonesia Stock Exchange. The number of samples of this study as many 7 banking companies with total of 35 data. This research method is quantitative research. The results of this study indicate that firm size variables have a significant positive effect on intrinsic value of stock, while sales growth, dividend policy and rupiah exchange rate do not influence intrinsic value of stock with price earning ratio approach.
Influence of Synchronization Signal Inaccuracy on DVB-T2 Local Content Insertion
Authors: Kuharskaya O. V. , Savin E. Z.
Published: May 2019

The article is aimed at specifying criteria of synchronization signal inaccuracy when DVB-T2 system local content re-placement cannot be carried out. Some settings of digital information stream are set as the initial data. The first part of the article specifies network delay calculation method. The second part of the article considers the signal cycle instability impact on estimation of local content device delay during its insertion in global information flow. Network delay saw-toothlike dependence on time is revealed, statistical parameters of synchronization signal instability are specified.  The third part of the article deals with analysis of method of substitution of two independent information flows by regionali-zation device. A model of T2 superframes comprising baseband frames (BB frames) which belong to different physical layer pipes (PLP) is described. The conditions under which the local information insertion becomes impossible are de-fined. Besides, the article considers other reasons of failure during single frequency networks (SFN) processing of local content insertion dealing with synchronization error at different stages of information flow digital content generation and delivery to DVB-T2.
Efficiency of the Miniature Anti-jam GNSS Antenna Array
Authors: Nemov A. V. , Nemov D. A. , Minh D. L. , Saveliev S. A. , Plastikov A. N.
Published: May 2019

The use of the miniature controlled reception pattern antennas (CRPAs) in GNSS equipment is one of the trends in GPS, Baidow, GLONASS development. A miniaturized GPS antenna array technology reduces the size of the antenna elements and the array dimensions. Miniature CRPAs are in demand not only with mass consumer of GPS/GLONASS house-hold equipment, but with expert users of complex hardware as well, where high-tech multi-sensor miniature antenna systems (AC) can be applied. Such types of AC used for intelligent control of spatial selectivity are considered as antenna arrays. The advantages of miniature CRPAs with anti-jamming capability include possibility to be installed on vehicles where it used to be impossible due to their size. The negative effect of miniaturization is in degradation of some antennas characteristics, such as gain, suppression of the reverse lobe of radiation pattern (RP), a heterogeneity of RP. In miniature antennas, the resonator interinfluence increases, that leads to distortion of individual emitters RP and to the in-crease of the total RP lobe of the antenna array irregularity, as well as the width of RP lobe. Designers take special measures to reduce the interinfluence of the resonators. However, they are not fully described in the available literature. Therefore, the achieved performance of miniature CRPAs is in great interest. The final criterion (from a consumer point of view) is in effective functional of a device containing a miniature CRPA, the degradation of its parameters in compare with traditional CRPA equipment of expert users. The authors focus on property investigation of miniature CRPAs manufactured primarily by US industry. Specifications of two antennas and some expected details of the miniaturized antenna array technology are described along with the test results of their ability to perform the objective function jammer suppression. The article contains the results obtained from independent testing of electrodynamics parameters of miniature L1/L2 frequency CRPA and its design analysis. The experimental data of sensor interinfluence are outlined. The measures to reduce the sensor interinfluence are take into account. The efficiency of the miniature antenna is estimated in the process of interference suppression by means of computer simulation. The Monte-Carlo method is applied. For the sake of generality, two types of algorithm for interference suppression are used.
Time Discriminator for Satellite Radar Altimeter Tracker System
Authors: Borovitsky D. S. , Zhesterev A. E. , Ipatov V. P , Mamchur R. M.
Published: May 2019

The article deals with the study of quasi-optimal TOA discriminator of an onboard echo-signal tracker of the altimeter carried by a space vehicle. In modern space-based altimeters, final data processing is imposed on the ground-based center receiving information from the spacecraft through a telemetry line, while the main task of an onboard delaylocked loop is to reliably retain the received echo-signal within the tracking window. The optimum discriminator of an onboard loop providing the potential accuracy of time measurement can appear difficult to implement. In the discriminator considered an error signal is proportional to the time mismatch between the half power point of the received power pattern and the tracking window. The equation for the equivalent time fluctuation variance is derived. It is also found that the discriminator proposed is as good at tracking precision as the maximum-power-point discriminator and maximums teepness discriminator, being at the same time much more attractive in terms of hardware complexity. The theoretical results are well consistent with the computer simulation. This simulation is performed both directly and using different methods of censoring the error signal at the discriminator output to effectively neutralize possible abnormal errors that are not taken into account by theoretical analysis.
Mutual Inductance of Two Coplanar Rectangular Contours with Symmetrical Internal Arrangement
Authors: Tsitsikian G. N. , Senchenko A. I.
Published: May 2019

The expediency of developing expressions for mutual inductance of rectangular and square coplanar contours is caused by configuration of frame antennas typical for RFID-technologies. Expressions presented in this article are aimed at simplifying calculation of induction coefficients when designing loop antennas. Expressions for mutual inductance of rectangular coplanar contours with symmetrical internal arrangement are obtained on the basis of the method of sections. It is shown that under certain conditions the expressions obtained can be reduced to intrinsic inductances of the square and rectangular frames encountered in antenna configurations. The analysis allows to estimate regions of resonance frequencies of frame receiving antennas. Simultaneously, a comparative analysis of a number of expressions for the intrinsic inductance of rectangular and square frames is performed, and attention is drawn to the difference in estimates. Recommendations for clarifying square contour external inductance are provided.
Choice of Modulation Mode and Satellite-Based Radar Altimeter Parameters
Authors: Borovitsky D. S. , Zhesterev A. E. , Ipatov V. P. , Mamchur R. M.
Published: May 2019

Satellite altimeters play a key role in Earth remote sensing programs. To attain a centimeter accuracy level within the limited energy budget the altimeter probing signal should have a processing gain of the order of tens of thousands. Un-der such circumstances both of the angle modulation modes (LFM, BPSK) are equivalent as for their tactical performance. Preference of LFM in modern foreign devices is based on the tendency to reduce demands to digital processing operation speed by transferring wide-band processing to the analog receiver part. However, modern circuitry capabilities allow to implement digital processing of the signals with the bandwidth of hundreds MHz, giving thereby the way to involving BPSK signals which are not that susceptible to various drifts and external disturbances, do not require frequency modulation super-linearity, etc. In the paper both modulation formats are compared and recommendations are given on how to choose the structure and parameters of BPSK signal.
Ideas and interests, economic policy and institutions
Authors: Tambovtsev Vitaly L.
Published: May 2019

In recent years an approach has appeared in economic policy analysis, the followers of which try to argue that ideas not only matter but cause economic policies and economic institutions change, and after all cause change in economies: an ideational approach. The purpose of the paper is to analyze the approach’s argumentations, estimate its validity, reveal strengths and weaknesses. Whereas this approach embraces many different aspects of economic processes, this paper turns attention to only two issues: ideas’ influence on policies and policies change, and the role of ideas in institutional change.
Does the investment climate rating influence the economic development of the region?
Authors: Kartaev Philipp S. , Polunin Konstantin E.
Published: May 2019

The paper examines the impact of improving the characteristics of the national investment climate rating of a subject of the Russian Federation on economic development. Based on the analysis of regional panel data for the period from 2014 to 2018, it was shown that an increase in the rating of a region is associated with an inflow of investments and an increase in GRP. One of the identified channels of this influence is associated with the market of highly skilled labor. It is demonstrated that, given the inaccessibility of detailed information about the results of the regions development to investors, the rating does not fully function as a signal to them. Based on the obtained results, the recommendations for improving the rating methodology were formulated.
A Study on Security Issues in the Internet of Things (IoT)
Authors: Ravikumar K. , Praksh S. Ramesh
Published: May 2019

Remote correspondence systems are exceedingly inclined to security dangers. The actual uses of remote correspondence systems come in military, business, medicinal services, retail, furthermore, transportations. These frameworks utilize wired, cell, or adhoc systems. Our methodology depends upon vitality mindful types of the IoT application's plan in the BIP (Behavior, Interaction, Priority) segment system. This takes into account a nitty gritty formal portrayal of the framework's conduct and its resulting approval, consequently giving input to improvements in the pre-arrangement or pre-creation stages. The structure and advancement of a property security framework, in light of human movement identification and remotely checking innovation, to affirm guest personality and to manage Door openness has been accounted for in this paper. This paper portrays in regards to the execution and sending of remote control framework and openness directly into a property situation for confirmed individuals because it were. A PIR movement sensor and Camera module are utilized to identify movement and catch pictures separately are dedicatedly make the security framework alive as per the solicitation. Electromagnetic entryway lock module work the entryway openness, has been structured and created.
Cirugía bariátrica en adolescentes
Authors: Amezquita G. Maria Virginia , Baeza L. Cecilia , Ríos E. Matías , Francesetti M. Valeria , Rybertt V. Vivian , Gutiérrrez R. Mariolly
Published: May 2019

La epidemia de obesidad afecta en forma transversal a todo el ciclo vital. En particular, en las últimas décadas se ha observado un incremento de la obesidad severa en adolescentes. En esta etapa de la vida caracterizada por profundos cambios físicos, emocionales y gran vulnerabilidad, la obesidad severa tiene pocas opciones efectivas de tratamiento. En adolescentes, los resultados del tratamiento centrado en modificaciones del estilo de vida son modestos y el arsenal farmacológico muy acotado y de poca efectividad. La Cirugía Bariátrica (CB) ha surgido como una opción terapéutica viable para un grupo seleccionado de adolescentes. El objetivo de esta revisión es presentar una visión actualizada respecto a indicaciones, contraindicaciones, complicaciones y resultados de estos procedimientos en población adolescente.
Impacto del Material Particulado aéreo (MP2,5) sobre las hospitalizaciones por enfermedades respiratorias en niños: estudio caso-control alterno
Authors: Matus C. Patricia , Oyarzún G. Manuel
Published: May 2019

Santiago de Chile con 7 millones de habitantes alcanza elevados niveles de contaminación atmosférica en invierno, el material particulado habitualmente excede los estándares de la OMS. Objetivo: Evaluar la influencia de la contaminación atmosférica por material particulado en las hospitalizaciones por enfermedades respiratorias en niños, entre 2001 y 2005 en la Región Metropolitana de Chile, independientemente de la presencia ambiental de virus sincicial respiratorio (VRS). Material y Método: 72 479 hospitalizaciones públicas y privadas por enfermedades respiratorias de niños menores de 15 años residentes en la región del estudio se analizaron con un diseño de caso control alternante, con estratificación temporal. Se evaluó principalmente: hospitalizaciones por enfermedades respiratorias (J00-J99), neumonía (J12-J18); asma (J21.0 - J21.9) y bronquiolitis (J45 - J46). Recopilándose diariamente temperatura, MP10, MP2,5, ozono, virus respiratorios (VRS) y humedad ambientales. Resultados: Los promedios de MP10 y MP2.5 fueron 81,5 y 41,2 µg/m3 respectivamente. El promedio de temperatura fue 12,8 ºC y de la humedad del aire 72,6 %. Un aumento de 10 µg/m3 de MP2.5 con 1 y 2 días de rezago se asoció con un incremento de las hospitalizaciones por enfermedades respiratorias cercano a 2%, este porcentaje aumentó a 5% cuando la exposición fue con 8 días de rezago, reflejando sinergismo entre material particulado y virus respiratorio (VRS). Conclusión: La exposición breve a contaminación atmosférica puede provocar hospitalizaciones por enfermedades respiratorias en niños.
The determination of acute toxicity parameters of “Imkar-120”
Authors: Fotina A. A. , Levytska V. A.
Published: May 2019

Vector-Borne Diseases are a variety of infectious and invasive diseases of animals and humans, the agents of which extend from one to another susceptible subject with the participation of hemopoiesis (ticks, insects, etc.). For the purpose of treatment of blood parasitic transmissive diseases, domestic and foreign researchers tested a significant number of drugs of different chemical composition. In connection with the insufficient on the domestic market of drugs on the basis of imidokarb dipropionate for the treatment of blood-parasitic diseases in animals, the Scientific-Production-Technical Enterprise “Brovapharma” established and conducted the state registration of the drug “Imcar-120”, which blocks the synthesis of polyamine; it also has significantly less toxicity than dimeters of aceturates. It provides a broad spectrum of antiprotozoal effects on pathogens of pyroplasmiosis of the genus Babesia (Babesia bovis, B. ovis, B. bigemina, B. colchica, B. equi, B. divergens, B. canis, B. caballi, B. gibsonii i Francaiella colchica); Teilerian species (Theileria annulata, T. sergenti, T. mutans, T. orientalis, T. ovis, T. recondita, T. tarandirangiferis); Nuttallia equi and the genus of Anaplasma (Anaplasma marginale, A. ovis, Ehrlichia canis) with their mono- or mixed infestation. Pre-clinical research “Determination of toxicological properties of the drug Imcar-120” was carried out on the basis of vivarium of the Faculty of Veterinary Medicine of Sumy NAU. Study of parameters of acute toxicity of the study drug was performed on 50 clinically healthy white mice in males and females. Before the experiment, the individual weight of the body of animals selected for the experiment was 18–22 g, the age was 8–9 weeks. In the first stage, preliminary experimental studies were conducted to determine the variation of dose limits before the main stage of the studies. At the same time the drug was administered intragastrically in doses: 2500, 3500, 4500, 5500, 6500, 7500 mg/kg. Each dose was given to three animals. After the introduction of the drug for monitoring animals, the experiment was carried out 14 days, the first day – every hour. For the expanded stage of the experiment, four experimental groups (n = 8) of animal analogues were formed, in which the study drug was injected under the same conditions as in the previous stage of the experiment at a rate of 3800, 4300, 4800 and 5300 mg/kg of body weight.  In the course of studies to determine the parameters of acute toxicity of the drug Imkar-120 it was determined half-lettable dose of the drug. According to R. Kerber's method, DL50 was 4456.25 mg/kg, therefore according to the classification of GOST 12.1.007-76 the preparation Imkar-120 should be classified as hazard class III by injection into the stomach – substances are moderately dangerous.
Morphological changes in cows’ mammary gland tissue under chronic form of mastitis
Authors: Mazurkevych A. Y. , Hryshchuk A. V. , Hryshchuk I. A.
Published: May 2019

Nowadays, there are many different methods for diagnosing cow’ mammary gland diseases. This is a clinical examination of the general condition of the animal, organoleptic, physico-chemical, bacteriological research of the secretion of the mammary gland, radiological, ultrasound, laser, histological, cytological diagnostics, etc. Since all these methods in most cases are aimed at evaluating functional changes in the mammary gland and do not reflect the structural changes of the organ, so in the development of therapeutic and preventive measures to prevent the occurrence of pathological processes in the mammary gland in cows do not display information on pathomorphological changes in the tissues of mammary glands for mastitis of various forms. Histological diagnostics becomes an integral part of the clinical examination of animals in the activity of the doctor of veterinary medicine, because it allows taking into account the changes occurring in the tissues of the mammary gland, not only on the macroscopic, but also on the microscopic levels, which is especially important in differential diagnosis. Microscopic studies of biopsy revealed that normally the wall of the lacrimal alveolus consists of a single-layer cubic epithelium, a layer of myoepithelial (basintine) cells, a basement membrane and perialveolar connective tissue that contains numerous blood and lymphatic capillaries and nerve fibers. On the internal walls of the alveoli, there are secretory cells (lactoxytes) which, at different stages of their accumulation of secretion, or its separation into the lumen of the alveoli. The entire lumen of the alveoli is completely filled with a secret, which is rather intensely colored with eosin. In damaged alveoli, we detected the destruction of in situ lacticates, their excretion into the lumen with subsequent destruction there. In the destruction and removal of a small number of lacto-cysts in the lumen of the alveoli was a formed secret, in which an increased number of lactocytes and single neutrophils and lymphocytes were recorded. The given results indicate the pathohistological changes in cows’ mammary gland tissues under the chronic form of the mastitis. The method can be used as one of the important tests in the differential diagnosis of mastitis, which makes it possible to carry out in-depth study of the structure of the mammary gland of cows for various types of pathology using the method of biopsy of tissues from the affected area and the histological examination of the biopsy. Histology, as the most important scientific instrument of biology and medicine, is the only way to detect pathological changes in the tissues of the mammary gland. That is why histology of breast pathology serves as the most accurate diagnostic method in veterinary medicine and helps to choose the most effective way of treatment.
The concentration of insuline-like growth factor in colostrum, milk and plasma of cows
Authors: Hrudetska D. V. , Simonov M. R. , Dashkovskyy O. O.
Published: May 2019

Recently, a significant amount of data has been reported indicating on the link between consumption of dairy products and development of oncological diseases. This could be explained by the presence in milk of various hormones, particularly insulin-like growth factor (IGF). This hormone is a mediator between somatotropin and tissues. In response to the increase of the blood level of growth hormone, hepatocytes begin actively synthesize the IGF, which accelerates the rate of the metabolism, including those of onco-cells. The majority of studies relate to humane medicine, and data on the dependence of IGF milk levels on breed, period of lactation, diet, physiological, and clinical status of an animal are lacking. Taking this into consideration, the purpose of this study was to analyze the concentration of insulin-like factor in colostrum, milk of cows and blood plasma at various stages of lactation. Study was performed on cows of Ukrainian black-and-white dairy breed in their from second to fifth lactation with milk yield 5100–5700 kg per previous lactation. Concentration of IGF was detected in colostrum, milk and plasma of cows, using enzyme immunoassay. Obtained material gives evidence that the highest IGF level is present in colostrum. After that hormone concentration decreases up to 10–14 day of lactation. High level of IGF in colostrum might be associated with necessity to stimulate metabolism of calves in early postnatal period of ontogenesis. Immediately after calving plasma level of IGF decreases. The highest level was observed on 10–14th days of lactation. Taking into consideration physiological function of the given hormone, there is no univocal explanation of the decrease of its plasma level in cows at the beginning of lactation. This could be associated with energy deficit, physiological condition of animals or with developing of lactation dominant and levels of other hormones. Potential of further research lies in investigation of the dependence of the IGF level in the secretion of the mammary gland on productivity, breed, age and diet of animals.
Dynamics of changes in protein metabolism rates in cows depending on the season of the year and the location of the farm
Authors: Vus U. M. , Kozenko O. V.
Published: May 2019

Protein metabolism in animals is perhaps the most informative indicator of anthropogenic environmental pollution, because it provides an opportunity to characterize metabolic processes in the body. They are of the utmost importance for the structure and function of all cells, tissues and organs. Proteins reflect the state of the organism, as well as those changes that occur in it under the influence of internal and external factors. We studied the dynamics of changes in indicators in protein metabolism in cows depending on the season of the year and the location of a farm. The research was carried out in two farms of the Lviv region: the Danylo Halytskyj LLC, near the State Mining and Chemical Enterprise “Sirka”, and FE “Lelyk” of Zhovkva district, in spring, summer, autumn and winter periods of keeping. The object of research was the blood of 20 cows of Ukrainian Black-Spotted breed. According to the results of the research, a reduction in total protein, relative to the physiological norm of 0.45 g/l. in spring, and by 0.64 g/l in the summer, dysproteinemia, a high level of gamma globulin fraction (50.30%) in cows from the Danylo Halytskyj farm, located in the zone of influence of the State Chemical Medicine Plant “Sirka”. In animals FE Lelyk, located in the conventionally clean zone, this indicator was significantly higher, and was 76.14 g/l in spring, and 78.17 g/l in summer, and also in animals of this farm dysproteinemia was not observed. In the autumn, at the end of the summer grazing period of the keeping, the index of total protein tended to decrease in the animals of the Danylo Halytsky's Ltd., and in winter it was normalized and invested in the limits of the physiological norm. Albumin fraction of protein in this group of animals, throughout the search period, had a tendency to increase. In the cows of the FE “Lelyk”, the indices of protein metabolism were within the limits of the physiological norm in all periods of research, with the inherent fluctuations in the season of the year. The obtained results due to the content of total protein and protein fractions in the plasma of blood of cows kept in territories with different ecological status indicate that the effect of the activity of the State Chemical Medicine Plant “Sirka” is sufficiently strong on the organism of animals.
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Authors: INAJOG INAJOG
Published: May 2019

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PENGARUH KOMPENSASI DAN KEPUASAN KERJA TERHADAP KOMITMEN PEGAWAI PT. LINTANG SARANA MEDIA MALANG
Authors: Apriyanti Apriyanti
Published: May 2019

Attention to Human Resources within an organization is critical to gaining employee commitment as expected. Employee commitment itself is influenced by many factors, including compensation and job satisfaction. This study aims to analyze the influence of Compensation and Job Satisfaction.
This study aims to clarify the effect of compensation and job satisfaction to employee commitment to the organization. Compensation should be able to trigger the desired behavior in organizations such good performance, loyalty and responsibility on organizational commitment. While job satisfaction is the compatibility between one's expectations that arise in return provided by the job. So if the company can provide appropriate compensation and employee expectations employee satisfaction with the job may have given the company, the employee will have a high level of commitment to the work place.
The population of this research is all the administrative staff of: PT.Lintang Sarana Media Malang The sampling technique used is total sampling with a sample of 40 people. Collecting the results was conducted by questionnaire and the results were analyzed using multiple linear regression analysis.
PENGARUH PEMBIAYAAN SYARIAH TERHADAP PENGUATAN MODAL UKM DI KOTA KENDARI
Authors: Ma’Mun Sitti Zakiah , Maesaroh Siti
Published: May 2019

Small and Medium Enterprises ( SMEs ) have a strategic role in economic development , on the other hand the inability of the SME sector in terms of capital constraints in increasing its production capabilities . Therefore the aim of this study wanted to determine the effect of strengthening the capital of Islamic finance to SMEs .The study site is located in the city of Kendari with a relatively small sample size ( 30 -50 ) are listed on the SME and SME Perindagkop Kendari . Sampling technique using a cluster sampling is sampling based on a predetermined area . with Islamic finance as the dependent variable and the capital structure of SMEs as an independent variable . Regression analysis is used as an analytical tool to determine the relationship and the influence of financing on the capital structure of SMEs , in order to improve the ability of capital ( capital gain ) . Results showed that the Syariah Financing affect the capital structure of SMEs in Kendari .
A Qualitative Course-Based Inquiry into the Concept of Love as a Central Component of Child and Youth Care Practice
Authors: `Schneider Kylie , Dziwenka Melanie , Schweighardt Bobbi , Bellefeuille Gerard
Published: May 2019

Child and Youth Care (CYC) students have the right to be engaged in pedagogical practices that inspire and arouse their curiosity about their field of practice. Undergraduate course-based research in which students have an opportunity to conduct authentic research within a for-credit course is one such high-impact pedagogical practice with a growing body of evidence-based outcomes. This article presents an undergraduate course-based research project that examined child and youth care student’s beliefs about displaying love as a component of their practice. Located in the constructivist/interpretive research paradigm, this course-based research project collected data through the use of an expressive arts-based data method followed by a semi-structured questionnaire. Four overarching themes were identified during the thematic analysis: (a) authentic caring involves expressions of love, (b) expressions of love are an essential component of growth and development, (c) loving care as an ethic of relational practice, and (d) but…professionalism stands in the way. The results of this course-based study suggest that expressing love as a component of relational-centred CYC practice is not fully understood by CYC students and that much more research is needed to explore this issue.
ANALISIS PENGARUH NON PERFORMING LOAN DAN DANA PIHAK KETIGA TERHADAP PEMBERIAN KREDIT UMKM OLEH BANK PERSERO DI INDONESIA
Authors: Purba Darwin Marasi , Teriana Deska
Published: May 2019

Penelitian ini membahas variable rasio keuangan perbankan yaitu Non Performing Loan (NPL) dan Dana Pihak Ketiga (DPK) yang dinilai mempengaruhi pemberian kredit UMKM oleh Bank Persero di Indonesia. Sampel yang digunakan dalam penelitian ini terdiri dari semua bank persero yang ada dindonesia periode 2010-2015. Metode pengambilan sampel menggunakan metode purposive sampling. Data yang digunakan dalam penelitian adalah data sekunder yang didapatkan dari publikasi statistik perbankan indonesia yang diterbitkan oleh Bank Indonesia ataupun Otoritas Jasa Keuangan. Analisis data menggunakan alat analisis regresi linier berganda yang sebelumnya telah dilakukan uji asumsi klasik, terdiri dari uji multikolinearitas, uji autokorelasi, dan uji heteroskedastisitas. Hasil dari penelitian ini menunjukkan bahwa NPL berpengaruh negatif signifikan terhadap Pemberian Kredit UMKM. Sementara DPK berpengaruh positif signifikan terhadap Pemberian Kredit UMKM. Besarnya uji derajad determinasi (Adjusted R Square) adalah sebesar 0,597 yang berarti bahwa variabel independen NPL dan DPK secara bersama-sama berpengaruh sebesar 59.7% terhadap kredit UMKM. Sedangkan, sisanya 40,3% dijelaskan oleh variabel lain diluar model penelitian ini. Kata Kunci: Non Performing Loan (NPL), Dana Pihak Ketiga (DPK), Bank Persero, Kredit Usaha Micro, Kecil dan Menengah.
Measurement and Utilization of Acoustic Emission for the Analysis and Monitoring of Concrete Slabs on the Subsoil
Authors: Pazdera Luboš , Cajka Radim , Topolář Libor , Mateckova Pavlina , Bilek Vlastimil , Sucharda Oldrich
Published: May 2019

The article deals with the field of use of acoustic emission (AE) measurement in engineering structures. The research particularly focuses on the assessment of acoustic emission during an experimental test of the load-carrying capacity of concrete slabs on the ground. A wider field of research includes structural and material optimization of advanced engineering structures. The tests of concrete slabs are then carried out in an alternate solution which differs in the used concrete or steel fibre reinforced concrete (FRC). The experimental program then includes typical measurement methods using displacement sensors and strain gauges. Non-destructive methods of measurement including acoustic emission have been used with an eye to the configuration of the experiment and deeper understanding of the actual behaviour and damage to the structure allowing for subsequent optimization and non-linear simulation of slab computation. The aim of the submitted article is to present and assess the acoustic emission as a non-destructive method which can be used to detect damage and determine the load-bearing capacity of the selected type of a FRC structure.
Is vegan feeding advisable in first childhood?
Authors: Salinas Carmen Martín
Published: May 2019

Objective: To analyse if it is possible to correctly feed children with a vegan diet from birth.

Method: A two stages bibliographic search was conducted. The first one was in Google Academic Search, using the information obtained for the introduction. The second one in the Health Science Database PubMed, Cinhal and Scopus where 26 publications were chosen.

Results: The principal nutrient deficiencies that can be developed in vegan children were identified. Aferwards the growth curve of both vegan and omnivore children has been compared. In addition, we have clarified the nurses’ knowledge about people’s vegan nutritional requirements from birth. Finally, the benefits of following a vegan diet have been established.

Discussion and conclusions: well-planned vegan diets allow an adequate development of children from birth. The only compulsory nutrient supplementation is vitamin B12. The healthcare professionals have an important role since they have to give the guidelines to introduce the complementary feeding. Also, they have to inform the parents how to avoid the nutritional deficiencies that can give rise to serious health consequences.

Keywords: Infant, Child, Vegan diet, Vegetarianism, Nursing.
Optimized modern regional system of provision of ophthalmic care to the population in the conditions of multiform health system
Authors: Dufynets V.A. , Hruzeva T.S.
Published: May 2019

Introduction. In today's conditions of the epidemic of non-infectious diseases, the significant increase in the incidence of diseases of the eye and its adnexa, disability due to eye diseases, including blindness, providing the population with affordable and quality medical care is a priority of any country. This requires the introduction of modern organizational models for providing ophthalmic care in terms of multiform health system.

The Aim of the Study. the rationale for a modern regional system of provision of ophthalmic care to the population in conditions of multiform health system.

Material and Methods. In the course of the study bibliographic, epidemiological, medical-statistical, sociological methods were used.

Results. The study identified shortcomings in the organization and provision of ophthalmic services to the population of the region, lack of resources to ensure the real needs of the population in ophthalmic care, low level of cooperation between communal and private health care institutions.

A high need for ophthalmic services was identified in view of the increase in incidence (by 41.7 %) and prevalence (47.1 %) of eye diseases among the population of the region during 2000–2015 and overload in the work of the ophthalmic service, as evidenced by the significant occupancy of profile beds throughout the year (360.7 days), short treatment terms (6.8 days) and high rates of bed turnover (53.1), with lower than the average in the country of provision population by specialists of the ophthalmologic profile (by 19.6 %).

This, along with other factors, negatively affected the availability and quality of medical services, which is confirmed by the results of a sociological survey. In contrast, from 69.7 to 92.2 per 100 respondents highly estimated the quality of service in private institutions, with their full availability for 54.3 per 100 respondents.

Based on the results of the research and taking into account the strategic directions of the development of the domestic health care system, recommendations of international organizations, the author justified the modern regional system of providing ophthalmic care to the population in the conditions of multiform health care and its administrative, normative-legal, information-analytical, educational-methodological, research, communicative functions.

Conclusions. The modern regional system of provision of ophthalmic care to the population in the conditions of multiform health system will increase the accessibility and quality of ophthalmic services to the population of the region, optimize the formation and distribution of resources for health care, create a competitive environment, increase the level of cooperation between health care institutions of various forms of ownership with positions of the patient-oriented approach, to introduce modern medical-organizational and medical-preventive technologies into the work of medical institutions.
Urgency the problem of determining polycyclic aromatic hydrocarbons (PAHs) in food products in accordance with the EU regulations
Authors: Chmil V.D. , Golokhova O.V. , Vydrin D.Yu. , Kruk V.I.
Published: May 2019

Goal. An analytical review of literature on the current state of the problem of the determination of polycyclic aromatic hydrocarbons (PAHs) in food products and discussion of ways to introduce EU norms into the practice of domestic laboratories that control the content of PAHS in foods.
Exertional Heatstroke, Asesmen Cepat Dan Penatalaksanaan Tepat: Laporan Kasus
Authors: Melinda  , Yofrido Filipus Michael Yofrido , Setiawan Philia
Published: May 2019

Heatstroke is the most severe heat illness which homeostatic thermoregulatory mechanism is failed, characterized by an elevation of the core body temperature above 40 oC, central nervous system dysfunction, and possible multi-organ failure. Heatstroke is the third leading cause of death among athletes. Exertional heatstroke (EHS) is exercise-induced; usually affects young healthy people during strenuous physical activity and have not acclimatized to environmental heat stress. Frequently encountered complications include encephalopathy, acute respiratory distress syndrome, myocardial injury, acute kidney injury, hypoglycemia, intestinal ishemia or infarction, pancreatic injury, rhabdomyolysis, disseminated intravascular coagulation (DIC), hypocalcemia, lactic acidosis, and hepatic failure. Immediate cooling is the cornerstone of treatment which evaporative cooling is preferred. Aspiration and seizure are common; airway management, oxygenation, and ventilation have to be adequately maintained. Crystalloid-fluid resuscitation is essential, averaging 1200 mL in first 4 hours. Systemic complications of heatstroke should be well-managed to prevent worse outcome. A case of 32-years-old man with no significant medical history was brought to emergency department after collapsing while running into the 20-kilometres marathon. He was unresponsive (GCS E1V2M1), had serial generalized seizure and hematemesis-melena. On primary survey, the patient was shocked (BP 67/24 mmHg, HR 165 bpm, cold extremity), tachypnea (41/min), hyperthermia (40.5oC rectally), SpO2 95% on simple mask 10 L/min. His laboratory results showed full-blown complications of heatstroke. Immediate rehydration therapy using saline solution and colloid solution intravenously was started, followed with blood or blood component transfusion. Tracheal intubation and mechanical ventilation were performed. During the intensive treatment, he became fully conscious and was extubated on hospital day 7. He was hemodynamically stable without any support, but developed multi-organ failure. Unfortunately, on twentieth day, he was cardiac arrest during hemodialysis and died four days later.
MUSCLE WASTING AFTER 48 HOURS OF FOOD DEPRIVATION DIFFERS BETWEEN MOUSE STRAINS AND IS PROMOTED BY MYOSTATIN DYSFUNCTION
Authors: Minderis Petras , Libnickienė Indrė , Ratkevičius Aivaras
Published: May 2019

Background. Genetic factors play an important role in determining muscle mass. Indeed, myostatin dysfunction
is associated with a pronounced muscle hypertrophy. The aim of our study was to test the hypothesis that starvation
induced muscle wasting differs between BEH+/+ and C57BL/6J strains of mice and myostatin dysfunction prevents
muscle wasting in BEH strain.
Methods. 18-week-old males of C57BL/6J, BEH+/+ and BEH were subjected to 48 h food deprivation (FD).
C57BL/6J mice were representatives of classic mouse strain. BEH mice which differ from BEH+/+ mice by Compact
mutation in the Mstn gene represented a model for myostatin dysfunction. All mice were divided into experimental
and control groups. The control groups consisted of mice fed ad libitum. Seven mice were studied in each group.
Mice were weighed before as well as 24 h and 48 h after FD which was followed by dissection and weighing of the
hindlimb skeletal muscle.
Results. BEH and BEH+/+ mice showed a similar (16.9 ± 1.4% vs. 19.3 ± 2.4%, p > .05) loss of body mass
while loss of body mass in C57BL/6J mice was the greatest (24.8 ± 1.9%, p < .001) after FD. The loss of muscle
mass was significant in both BEH (p < .001) and C57BL/6J (p < .01) mice, but it was below the level of significance
(p > .05) in BEH+/+ mice.
Conclusions. Myostatin dysfunction promotes muscle atrophy after FD. During short periods of FD, BEH+/+
mice are more resistant to body and muscle loss compared to C57BL/6J mice.
Creative Responsiveness, Dramatic Performance, and Becoming-Democratic
Authors: Goktepe Katherine
Published: May 2019

This article draws upon work by Gilles Deleuze, Sanford Meisner, and William Connolly to argue that the practice of acting helps citizens to encounter unsettling circumstances in daily life; respond to and connect with others in more open, interactive ways; and expand the relatively stable repertoire of selves each person cultivates through life. Considering scenes from the films of Anna Magnani, Ronald Reagan, and Joan Crawford, I argue that acting spaces can be sites where an exploration and decentring of subjectivity can proceed and new modes of democratic interaction and togetherness can be enacted.
Anarchism in Deleuze
Authors: Kaluža Jernej
Published: May 2019

In this article, we argue that Deleuze's philosophy could be understood as anarchistic in a specifically defined meaning. The imperative of immanence of thought, which we explicate mainly through the reading of Deleuze's Spinoza, on the one hand establishes indivisibility between theory and practice and on the other hand paradoxically orders disobedience. We argue for a thought that is immanent, adequate with its inner practice, for thought that cannot be forced. That is the basis on which we combine the reading of Deleuze, Spinoza, Nietzsche and some basic ideas from the contemporary anarchistic movement (Graeber) and the anarchistic tradition (Stirner). We do not try to argue for a certain form of political action. Our goal is to establish a field of thought, that is by its innermost ontological principles anarchistic: practice must be accompanied by its own theory. Adequate thought cannot be forced. This is a necessary condition for each consistent practice-theory.