bluuebunny/crossref_metadata_2025 huggingface dataset:
Outcomes in grade 3B follicular lymphoma: an international study led by the Australasian Lymphoma Alliance
Authors: Barraclough Allison , England James T. , Villa Diego , Wight Joel , Hapgood Greg , Conn Jason , Doo Nicole Wong , Li Eric Wenlong , Gilbertson Michael , Shaw Briony , Bishton Mark J. , Saeed Malik , Ratnasingam Sumita , Abeyakoon Chathuri , Chong Geoff , Wai Shin Hnin , Ku Matthew , Lee Hui-Peng , Fleming Kathryn , Tam Constantine , Douglas Genevieve , Cheah Chan Y. , Ng Zi Yun , Rolfe Tukten , Mills Anthony K , Hamad Nada , Cashman Helen , Gleeson Mary , Narayana Manjunath , Hawkes Eliza A.
Published: February 2023

Grade (G) 3B follicular lymphoma (FL) is a rare FL subtype which exists on a histological continuum between ‘low-grade’ (Grade 1, 2 and 3A FL) and diffuse large B-cell lymphoma (DLBCL) appearing to share features with each. Clinical characteristics and outcomes are poorly understood due to lack of adequate representation in prospective trials and large-scale analyses. We analyzed 157 G3BFL cases from 18 international centers, and two comparator groups; G3AFL (n=302) and DLBCL (n=548). Composite histology with DLBCL or low-grade FL occurred in approximately half of G3BFL cases. With median 5 years follow-up, G3BFL overall (OS; P
Tratamiento de estenosis ureteropelvica e hidronefrosis. Una revisión bibliográfica
Authors: Guacho Juan Sebastián , Avendaño Torres Mishell Francesca
Published: February 2023

Introducción: La estenosis ureteropelvica es una estrechez a nivel de la unión pelvis renal con el uréter la cual evita el paso de la orina y su expulsión, por lo que causa secundariamente hidronefrosis. Existen varias etiologías como las intrínsecas o congénitas y las adquiridas, en donde se observan con más frecuencia las congénitas. Provoca manifestaciones clínicas como el dolor, hematuria, infecciones de vías urinarias a repetición y secundaria a esta, hematuria. El diagnostico puede ser prenatal con la ayuda de la ecografía, además de exámenes más específicos como la cistouretrografia miccional, renografia diurética, entre otros descritos posteriormente. Objetivos: General: Elaborar un artículo de revisión bibliográfica actualizada sobre el tratamiento de estenosis ureteropélvica e hidronefrosis. Específicos: Determinar las etiologías más comunes de la estenosis ureteropélvica e hidronefrosis. Conocer el cuadro clínico y exámenes complementarios asociados a la estenosis ureteropélvica e hidronefrosis. Proporcionar una herramienta para el diagnóstico precoz de la estenosis ureteropélvica. Describir el manejo adecuado de la estenosis ureteropélvica según requiera el paciente Metodología: Mediante bases de datos como PUBMED, UpToDate, PMC, ELSEVIER, the Cochrane Library Plus, NCBI se realizó la búsqueda exhaustiva de artículos científicos para el desarrollo de un estudio descriptivo mediante una revisión bibliográfica actualizada de forma sistemática. Resultados: Los principales hallazgos arrojan que existe mayor eficacia de la pieloplastia mínimamente invasiva con un 7% de tasa de fracaso, la pieloplastia abierta 9% y la endopielotomia 15%. Conclusiones: La estenosis ureteropelvica está causada generalmente por etiología congénita. Los pacientes lactantes con esta patología suelen ser asintomáticos, ya que con el pasar del tiempo este problema tiene su solución, sin embargo, si no existe resolución después de los 18 meses, existirán manifestaciones como dolor abdominal, puede existir la presencia de masas abdominales, hematuria. La intervención quirúrgica es el estándar de oro para el tratamiento de esta patología.
Information and analytical support of activity of the NAPS of Ukraine as one of the priority areas of work V. O. Sukhomlinskyi SSPL of Ukraine
Authors: Sereda Khrystyna
Published: February 2023

Information and analytical support of activity of the NAPS of Ukraine as one of the priority areas of activity of V. O. Sukhomlinskyi SSPL of Ukraine is characterized in the article.
Requirements are to the programmatic and vehicle platforms for the construction of educational portals
Authors: Sereda Khrystyna
Published: February 2023

The presentation presents the requirements are to the programmatic and vehicle platforms for the construction of educational portals.
Экспериментальное исследование огнестойкости подвесного потолка, выполненного с применением негорючих гипсовых плит
Authors: Кудряшов Вадим Александрович , Ботян Сергей Сергеевич , Коба Станислав Сергеевич , Королев Александр Владимирович , Лойко Юрий Леонидович
Published: February 2023

Цель. На основании анализа технических решений, применяемых для устройства огнестойких подвесных потолков с использованием гипсовых негорючих плит, разработать типовой образец фрагмента для натурных испытаний с воздействием огня снизу (со стороны помещения). Провести огневые испытания и определить огнестойкость экспериментального образца, получить температурно-временные зависимости для локальных точек испытываемого фрагмента, наиболее подверженных разрушениям и деформациям в результате нагрева.
Методы. Анализ результатов существующих исследований и методов для достижения целей исследований. Разработка типового образца для испытаний согласно требованиям СТБ EN 1363-1-2009, СТБ EN 1364-2-2009. Разработка методики определения температурно-временных зависимостей при нагреве для локальных точек образца огнестойкого подвесного потолка. Экспериментальные огневые исследования.
Результаты. Огнестойкий подвесной потолок с применением гипсовых негорючих плит является наиболее простым и распространенным решением для увеличения предела огнестойкости горизонтальных элементов перекрытий и покрытий. Для подтверждения технических решений, применяемых для устройства огнестойких подвесных потолков с применением гипсовых негорючих плит, был разработан типовой экспериментальный образец. Огнестойкий подвесной потолок, сформированный двумя сплошными слоями гипсовых негорючих плит марки Gyproc Fire общей толщиной 25 мм и двумя слоями минеральной ваты марки ISOVER 50/E/K плотностью 14±10 % кг/м3 общей толщиной 100 мм на несущем двухуровневом каркасе из тонкостенных профилей соответствует пределу огнестойкости EI 60 (a←b) согласно СТБ EN 1364-2-2009. Средняя температура на необогреваемой поверхности минераловатных плит составила 170 °С на 65-й минуте испытаний.
Область применения исследований. Полученные результаты огневых испытаний могут быть использованы в численном моделировании нагрева огнестойкого подвесного потолка при высокотемпературном воздействии, а также в практической деятельности как огнезащитное решение для строительных конструкций.
Измерение поглощенной дозы ионизирующего излучения с помощью оптических волноводных кольцевых резонаторов
Authors: Гончаренко Игорь Андреевич , Ильюшонок Александр Васильевич , Рябцев Виталий Николаевич
Published: February 2023

Цель. Анализ методов измерения и конструкций датчиков поглощенной дозы ионизирующего излучения на основе оптических волноводных кольцевых резонаторов.
Методы. Общая методология работы предусматривала использование теоретических методов исследования (анализ, синтез, сравнение).
Результаты. Проведен анализ воздействия ионизирующего излучения на волноводные микрокольцевые резонаторы и оценка возможности их использования в качестве датчиков поглощенной дозы. Показано, что с точки зрения чувствительности перспективными являются датчики на основе микрокольцевых резонаторов на базе кремниевых волноводов, покрытых фторполимером.
Область применения исследований. Результаты обзора и анализа сведений о методах измерения поглощенной дозы ионизирующего излучения могут послужить базой для создания эффективных дозиметров с высокой чувствительностью на основе оптических волноводных кольцевых резонаторов.
Совершенствование информационных систем о природных пожарах Республики Беларусь и Российской Федерации
Authors: Кравцов Сергей Леонидович , Попова Анастасия Константиновна , Маркова Дарья Сергеевна , Лепесевич Екатерина Вячеславовна , Решетник Сергей Владимирович
Published: February 2023

Цель. Достижение информационными системами о природных пожарах (ИСПП) Республики Беларусь и Российской Федерации современного уровня (как по степени автоматизации вычислений, так и по качеству представляемой информации) в ситуации уже изменившихся и ожидаемых погодных условий.
Методы. Качественно новый результат предлагается получить путем внедрения передовых технологий, основанных на обработке разнородных данных (наземных, спутниковых и т.д.) за длительный период времени, – подхода больших данных.
Результаты. Проведен анализ функционирующих в настоящее время ИСПП показавший, что существующие ИСПП Республики Беларусь и Российской Федерации, основанные на разработанных в 50-х гг. XX в. комплексных метеорологических показателях и созданные отдельно друг от друга без единого видения облика системы, осуществляют прогнозный мониторинг пожарной опасности на недостаточном для современных условий уровне, существенно уступая зарубежным аналогам.
Сформулированы предложения по совершенствованию ИСПП Республики Беларусь и Российской Федерации таким образом, чтобы они представляли собой комплексные системы, охватывающие полный цикл прогнозного мониторинга пожарной опасности: от предупреждения и подготовки к природным пожарам до анализа причиненного ими ущерба. Для более полного отражения картины пожарной опасности и учета особенностей изменившихся погодных условий предлагается перейти от комплексных метеорологических показателей Н.А. Диченкова (принят в Республике Беларусь) и В.Г. Нестерова (принят в Российской Федерации) к индексу пожарной опасности по метеорологическим условиям FWI (Fire Weather Index, FWI). Это также позволит гармонизировать оценку пожарной опасности на территории Республики Беларусь, Российской Федерации и прилегающих стран.
Область применения исследований. Изложенные предложения могут быть использованы при совершенствовании ИСПП Республики Беларусь и Российской Федерации.
Shear Resistance of Members Without Shear Reinforcement in Presence of Axial Forces in the Next Eurocode 2
Authors: Miguel Pedro F. , Fernández Miguel A. , Hegger Josef , Schmidt Maximilian
Published: February 2023

The second generation of Eurocode 2 incorporates formulations based on physical models which are general enough for the assessment of existing structures but can be simplified for the design of new structures, in order to improve the ease-of-use. One of the areas where these improvements are addressed is the shear verification of members without shear reinforcement, such as solid slabs, walls, cut-and-cover tunnels, precast ribs or hollow core slabs, which in some cases are prestressed or subjected to external axial loading.In current Eurocode 2, the shear verification of these structures is based on an empirical formulation proposed by Zsutty in 1968. The final draft of the new version of Eurocode 2 has adopted the Critical Shear Crack Theory (CSCT) as the theoretical basis for the formulation of the shear resistance, which allows a better understanding of structural behaviour in many different conditions, not only for the design of new structures, but also for the assessment of existing structures. This formulation accounts for some aspects that are not well considered in current Eurocode 2, which have been underlined as shortcomings in recent years.The formulation for design of new structures in the final draft of the new version of Eurocode 2 (General Model) is easy to use for the verification of the shear resistance, but requires an iterative process to calculate the shear capacity of sections in the presence of axial forces. For this reason, the final draft of the new version of Eurocode 2 also provides an alternative non-iterative formulation (Linear Approach) to calculate the shear capacity in presence of compressive axial forces, based on the linearisation of the CSCT shear failure criterion and formulated with the same additive structure as in the current Eurocode 2, useful for the most common cases.This paper presents the General Model formulation provided in the next Eurocode 2 for the shear verification of axially loaded members without shear reinforcement, as well as the alternative formulation (linear approach). In addition, the agreement of both formulations with experimental results from an available shear test database on prestressed concrete beams is shown and the consistency of the safety treatment between the two formulations is also discussed.
Miért az első választás számos sebészeti kórkép kezelésében a negatívnyomás-terápia az általános sebészeti gyakorlatban? Irodalmi áttekintés
Authors: Szentkereszty Zsolt , Kolozsi Péter , Zádori Gergely , Susán Zsolt , Ötvös Csaba , Enyedi Attila , Tóth Dezső
Published: February 2023

A negatívnyomás-terápia (NPWT) széles körben alkalmazott módszer, elsősorban problémás sebek, lágyrész-fertőzések, szeptikus hasi folyamatok, abdominalis kompartment szindróma, nyelőcső- és végbélanastomosis-elégtelenség kezelésére. Sajnos a klinikai gyakorlatban sokszor csak mint „ultimum refugiumot” alkalmazzák. A kezelést a betegek jól tolerálják, az életminőség jobb, mint a konvencionális kezelés esetén. Az NPWT alkalmazása, kedvező hatásai miatt lerövidíti a kezelési időt, jobb korai és késői eredményekkel bír és költséghatékonyabb. A szerzők felhívják a figyelmet arra, hogy a vákuumkezelést megfelelő indikációk alapján minél hamarabb el kell kezdeni. A kezelés alatti életminőség, a kezelési idő, a költséghatékonyság, az eredményesség és az evidencia kérdéseinek elemzésével világítanak rá arra, hogy az NPWT sok esetben első kezelésként javasolt.
A fővárosi onkológiai CT- és MR-várólista-csökkentési program jelentősége és részidős eredményei, tapasztalatai
Authors: Rékassy Balázs , Maurovich Horváth Pál , Szanka Tímea , Papp Zsombor Mátyás , Takács Róbert , Salai Márton József , Dózsa Csaba László
Published: February 2023

HÁTTÉR – A nagy értékű orvosi képalkotó diagnosztikai eljárások kulcsfontosságú elemei az onkológiai betegség gyanújával rendelkező betegek klinikai vizsgálatának és a megkezdett terápia hatékonysága megállapításának. Magyarországon a magas diagnosztikai igények következtében a komputertomográfia (CT) vagy mágneses rezonanciás képalkotás (MR) diagnosztikai várólistái általában hosszúak és kevésbé átlátható leletezési időt eredményeznek, még a potenciálisan daganatgyanús egyéneknél vagy a diagnosztizált daganatos beteg terápiájának követése esetén is. A JELEN TANULMÁNY CÉLJA – Az Egészséges Budapest Program (EBP) keretén belül megvalósuló budapesti onkodiagnosztikai program félidős elemzése, a tapasztalatok leszűrése és a háttérben meghúzódó egészségpolitikai folyamatok bemutatása. EREDMÉNYEK – A Program keretében a Fővárosi Önkormányzat 2020 novemberétől 2022. december 31-ig 5437 kontrasztanyagos CT és 2948 MR, C-s vagy D-s iránydiagnózissal, az úgynevezett „ BP” térítési kategóriában beutalt eset vizsgálatát finanszírozta szektorsemleges módon köz- és magánegészségügyi képalkotó szolgáltatók felé. A Semmelweis Egyetem tanulmánya szerint az EBP-s betegek esetében a radiológiai vizsgálatok átlagosan 15,2 nappal gyorsabban megtörténtek (16,1 kontra 31,3 nap), mint a NEAK-finanszírozott esetekben, az átlagos várakozási idő a CT vagy MR-vizsgálatokra 13 nappal rövidült (4,2 nap, szemben a 17,2 nappal). Az esetek 86%-ában a betegek egyszer, 14%-ában kétszer vagy még többször vették igénybe a Programot. A Programon belüli igénybevétel ugyanakkor fővárosi kerületenként jelentős különbséget mutat: az eredetileg kerületi bontású – demográfiai, prevalencia- és incidenciaadatok alapján tervezett – esetszámkereteket az egyes kerületek CT esetében 3–45%, MR esetében pedig 8–37% közötti mértékben aknázták ki a kerületi lakosoknak, döntően a kerületi szakrendelői intézeti szakorvosok BP Programba való beutalása révén, a 2020. november és 2022. augusztus közötti időszakban. KONKLÚZIÓ – Az eredetileg a Covid-járvány előtt tervezett esetszámokhoz képest a Program kisebb mértékben került felhasználásra. A tervezett szakmai célkitűzéseket tekintve a CT és MR diagnosztikai előjegyzési idők és várólisták csökkenése révén a Program elérte hatását, illetve közvetve hatással van a budapesti képalkotó diagnosztikai várólisták csökkenésére, ugyanakkor ez önmagában nem elegendő a teljes onkológiai vizsgálati sor gyorsításához és rendezetté tételéhez. Emiatt a Programot további diagnosztikai elemekkel és beteg - útszervezési modulok irányába kívánjuk továbbfejleszteni.
Exploring The Use of Information Communication Technologies among Dairy Farmers to Improve Farm Productivity in Punjab Pakistan
Authors: Asghar Salman , Ashraf Ijaz , Ch Khalid Mahmood , Khan Bakht Baidar
Published: February 2023

This study was conducted to examine the impact of demographic attributes on the usage of information and communication technologies (ICTs) among dairy farmers in District Sheikhupura, which is a prominent area in terms of dairy potential and dairy households. The use of ICTs was aimed at improving dairy farm productivity through extended awareness and adoption of recommendations. Tota 383 randomly selected respondents were interviewed face to face on a structured questionnaire. The collected data were analysed using Statistical Package for Social Sciences (SPSS). Results indicated that 36% of farmers were aged between 36-50 years, 35.8% had no formal education, 60.1% had less than 5 acres of land and 37.6% had the experience of over 20 years. The chi-square test of association confirmed that education (P0.05), land size (P0.05) and monthly income (P0.05) were significantly associated with the use of ICTs. Whereas, age and experiences were insignificant (P0.05) with the use of ICTs. Multiple Regression analysis confirmed that age, education and size of landholdings had statistically significant relationships with the adoption of ICTs among dairy farmers.  This study, concludes that improvement in the socio-economic attributes of the farmers was associated with the improvement in the use of ICTs. Therefore, efforts are needed to improve the socio-economic conditions of farmers through farmer facilitation, subsidies, training and skills development regarding use of ICT gadgets.
AIMARISM: Dialectical creation of a "nation". Contexts between historical evidence and narrative.
Authors: Osorio Soto Gary
Published: February 2023

The Aymaraism, as a sociocultural phenomenon, has given rise to components and elements of representativeness within the population of the Andes. However, the dialectic component of the aymara as a nation is undermined by fundamental historiographical elements. Using the empirical analysis of the historical data, we conclude that the aymara language and culture contains ambiguous elements that cannot be defined according to the dialectical interpretation and the current narrative. The analysis of cultural, linguistic, and social elements of this population from the Early Horizon period to the present confirms the historical distortion towards a narrative component of origin and presence in the territory of the Qullasuyu. To understand this phenomenon, this work promotes the complementarity of the analysis through the use of ethnoarchaeological and documentary elements in order to clarify the origin, synthesis, and development of the aymara from a historical perspective, leaving aside the dialectic component of the present.
Perancangan dan Pengembangan Video Game sebagai Media Terapi Depresi
Authors: Rachmawan Rachmawan , Adnas Diny Anggriani
Published: February 2023

Depresi merupakan salah satu penyakit mental yang paling umum terjadi saat ini, penderita depresi biasanya memiliki gangguan emosional besar yang disebabkan oleh stress dan ketegangan yang dapat menimbulkan munculnya keinginan untuk bunuh diri seiring waktu. Teknologi telah berkembang pesat, terutama dalam bidang multimedia, multimedia membuat pengiriman seperti informasi dan pesan menjadi sangat cepat dan praktis di dalam waktu yang singkat. Video game termasuk ke dalam salah satu bidang di multimedia yang paling populer, video game memiliki popularitas yang besar khususnya generasi muda, video game dapat membantu mengurangi stress dan kecemasan pemainnya. Di penelitian ini, peniliti akan mengembangkan video game menggunakan salah satu game engine yang terkemuka yaitu Unity dengan metode Research and Development yang menggunakan model ADDIE (Analyze, Design, Develop, Implement, Evaluate). Video game yang dikembangkan merupakan game berbasis cerita tentang depresi dan perasaan dikucilkan. Hasil dari penelitian ini berupa game platformer 2D berbasis cerita pendek yang dibentuk dan disusun di Unity. Pengembangan ini diharapkan dapat membantu penderita depresi untuk melawan depresi dan meningkatkan kesadaran mengenai penyakit depresi di masyarakat luas.
SELEKSI FITUR INFORMATION GAIN DAN ALGORITMA NAÏVE BAYES UNTUK REVIEW OPINI KONSUMEN
Authors: Nurfaizah Nurfaizah
Published: February 2023

The growth of internet users in Indonesia is increasing, this is in line with online shopping habits or often referred to as e-commerce which continues to increase. Various things are done by e-commerce companies to maintain customer loyalty, one of which is through product evaluation using consumer opinion reviews. The number of reviews that are too many will be biased, so it is necessary to do a classification method that will help e-commerce companies to find out the extent of their customer loyalty. Consumer review becomes something important because all assessments of the products they buy are all in the review column. In this research, a consumer review is carried out using the Naive Bayes classification method and to improve the accuracy of attributes using the Information Gain feature selection and using the Select by Weight operator which will display the best attributes of the pre processing process. The review data set is taken from consumers' comments on Google Play. The results of this study are classifying consumer reviews into positive reviews and negative reviews with Cross Validation using 10 fold, the accuracy of the Naive Bayes method is 78.4% using the Information Gain feature selection method, the accuracy increases to 81.2%
Analisis Implementasi Sistem Informasi Akuntansi Dengan Menggunakan Accounting Software Pada PT Bisnis Teknologi Manajemen
Authors: Prima Argo Putra , Putri Anggia Dasa
Published: February 2023

Tujuan dari penelitian ini untuk mengkaji  penggunaan sistem akuntansi menggunakan  Microsoft Excel  yang diterapkan sebelumnya. Mengetahui keandalan sistem akuntansi yang digunakan sebelumnya. Megetahui  faktor-faktor yang mempengaruhi  kesuksesan  implementasi sistem informasi  akuntansi  berbasis  accounting software ABSS Accounting  pada  PT Bisnis Teknologi Manajemen Serta saat menggunakan Microsoft Excel dapat dirasakan para pengguna sistem ABSS Accounting apa yang menjadi keunggulannya. Mengkaji  penggunaan sistem akuntansi menggunakan  Microsoft Excel  yang diterapkan sebelum implementasi ABSS Accounting. Hasil dari penelitian ini adalah dalam Microsoft Excel tidak memiliki menu khusus  atau fitur yang dapat digunakan dalam penyajian laporan keuangan sehingga banyak proses yang harus dikerjakan secara manual sehingga dapat memiliki kelemahan dibanding dengan menggunakan software akuntansi. Sistem akuntansi yang digunakan saat ini yaitu ABSS Accounting, merupakan sistem akuntansi yang lebih memadai dan dapat diandalkan dari pada Microsoft Excel. ABSS Accounting dapat dikategorikan sistem yang kompleks karena memiliki fitur-fitur dapat digunakan sesuai dengan kebutuhan perusahaan. Yang membuat implementasi sistem informasi akuntansi berbasis ABSS Accounting dapat bemanfaat bagi PT Bisnis Teknologi Manajemen karena memiliki fitur-fitur yang lengkap yang dapat memudahkan  user serta dapat digunakan selamanya tanpa harus ada biaya tambahan untuk meng- update.
ADOPSI METODE PERSONA UNTUK PERANCANGAN APLIKASI TRAVEL AGENT BERBASIS ANDROID
Authors: Ananda Ibnu
Published: February 2023

Perancangan desain sebuah perangkat lunak (software) masih banyak terpaku pada user interface (UI) yang menarik bukan pada user experience (UX) meskipun sekarang sudah banyak yang memperkenalkan desain UX. Perancangan desain yang hanya terpaku pada UI akan berdampak buruk pada pengalaman pengguna saat menggunakan fitur-fitur yang disediakan aplikasi. Bahkan terdapat fitur yang sebenarnya tidak banyak digunakan pengguna dan dapat dihilangkan. UI terbaikpun tidak akan bermanfaat bagi masyarakat yang awam terhadap teknologi karena tidak mengerti bagaimana mengoperasikan aplikasi tersebut. Oleh karena itu metode persona perlu diadopsi untuk mengembangkan aplikasi pada travel agent di mana sistem yang dibangun akan didasarkan pada kebutuhan calon pengguna yang akan dijadikan target atas dibuatnya aplikasi ini. Dalam penerapan metode persona ini dibutuhkan beberapa tahapan yaitu pembuatan hipotesis dari data yang telah didapatkan penulis saat melakukan wawancara, melakukan verifikasi hipotesis tersebut kepada calon pengguna, menemukan pola, membangun persona, mendefinisikan situasi, melakukan validasi hingga menyebarkan pengetahuan. Hasil yang dicapai penelitian ini adalah desain aplikasi travel agent dengan fasilitas fitur yang sesuai kebutuhan calon pengguna dan UX yang baik.ont Times New Roman size 8 itali spasi single, maks 200 kata.
ANALISIS QOS VIDEO STREAMING JARINGAN WIRELESS (STUDI KASUS: TAMAN INTERNET ENGKU PUTRI BATAM)
Authors: Nopriadi Nopriadi , Arnomo Sasa Ani
Published: February 2023

The increasing number of internet users in Indonesia has an impact on increasing the number of users of streaming video. The increase in the number of users is based on technological developments with the emergence of mobile devices such as notebooks, tablets and smartphones equipped with internet access via wireless networks. Unlike networks using cables, the characteristics of using video streaming over wireless networks are limited when compared to those using cables. To access various applications on the internet, including video streaming, a stable internet service is needed. For this reason, a Quality of Service (QoS) measurement research is needed which is carried out at one of the wireless network provider points in the city of Batam, namely Taman Internet Engku Putri. QoS can be used to measure and analyze the stability and quality of a wireless network. The parameters used in the measurement and analysis of QoS are Throughput, Delay, Jitter and Pakect Loss which will be tested on video streaming services. The test will be carried out at certain times such as peak hours and low hours. Low hours usually range from 08.00 WIB - 15.00 WIB and rush hour usually ranges from 15.00 WIB - 21.00 WIB. The results of measurement and analysis using four QoS parameters show that the video streaming service using wireless networks in Taman Internet Engku Putri is in the medium category.
PERANCANGAN APLIKASI KEUANGAN BERBASIS ANDROID DI BATAM VERSI 2.0
Authors: Siyamto Yuli , Saputra Asron
Published: February 2023

Penelitian ini bertujuan untuk membangun suatu aplikasi Android  yang mampu membantu masyarakat Kota Batam utamanya bagi masyarakat menengah ke bawah dalam mengelola keuangannya. Kondisi perekonomian yang sulit dan diambang resesi akibat pandemic covid-19, memaksa masyarakat sangat-sangat cermat dalam memperhatikan pos-pos pengeluaran. Di kalangan masyarakat, pada umumnya malas untuk mengelola keuangan. Butuh pribadi yang teliti, disiplin dan konsisten dalam mencatat secara rinci. Apalagi banyak mitos yang melekat di masyarakat, semua sudah ada rezekinya, jalani saja seperti air mengalir. Dengan adanya perkembangan teknologi informasi serta kondisi masyarakat Kota Batam terkini yang telah familiar dengan smartphone, maka sangat tepat dikembangkan suatu aplikasi mobile. Aplikasi ini merupakan pengembangan dari aplikasi keuangan versi 1.0 yang telah dibangun dibangun sebelumnya. Metode pengembangan system digunakan SDLC dengan model waterfall. Hasil nyata dari penelitian ini sebuah aplikasi Financial Management 2.0 berbasis mobile yang sederhana, mudah digunakan, dan bermanfaat bagi masyarakat. Tingkat kesiapan teknologi penelitian ini adalah level 1 ke level 2, artinya aplikasi yang dibangun merepresentasikan formulasi konseb teknologi yang dapat tercapai. Tujuan akhir penelitian adalah diharapkan dapat membantu masyarakat Kota Batam lebih maju dan sejahtera.
Sorghum, millet and cassava as alternative dietary energy sources for sustainable quail production – A review
Authors: Mnisi Caven Mguvane , Oyeagu Chika Ethelbert , Akuru Eunice Amaka , Ruzvidzo Oziniel , Lewu Francis Bayo
Published: February 2023

Diversification and expansion of the poultry industry with fast-growing and highly prolific birds such as the quail (Coturnix coturnix), could contribute significantly in achieving global food and nutrition security. However, sustainable intensification of the quail relies on the cost of dietary ingredients used during feed formulations. The use of non-conventional energy sources such as sorghum, millet, and cassava in lieu of expensive energy sources such as maize, could ensure sustainable quail businesses. Generally, alternative feedstuffs should be cost-effective and possess comparable nutritional qualities as maize. In tropical countries such as South Africa, the use of sorghum, millet, and cassava in quail diets can serve as ideal alternatives because they have relatively comparable energy values as maize. Furthermore, these alternatives are largely available and easily accessible in many farming areas of South Africa. However, the presence of antinutritional factors such as tannins, cyanides and phytic acid, among others, as well as their high fiber levels may limit their utilization in quail nutrition. Nevertheless, attempts have been made to develop improved varieties with low antinutrient compositions, for instance, low-tannin sorghum varieties are increasingly being fed to poultry birds. Furthermore, there is growing evidence that certain processing techniques such as sun-drying, soaking, boiling and fermentation, among others, can lower the concentrations of antinutrients in these alternative feedstuffs, thus increasing their feeding value. To this end, nutritional feeding trials on the positive effects of sorghum, millet and cassava in quail nutrition are inconsistent, mainly due to differences in cultivar type, harvesting site or environmental conditions, sampling, and handling methods amongst other factors. Thus, the present review aimed to discuss the potential of substituting maize with sorghum, millet, and cassava in quail diets.
Injectable FHE+BP composites hydrogel with enhanced regenerative capacity of tendon-bone interface for anterior cruciate ligament reconstruction
Authors: Cho Eunshinae , Qiao Yi , Chen Changan , Xu Junjie , Cai Jiangyu , Li Yamin , Zhao Jinzhong
Published: February 2023

Features of black phosphorous (BP) nano sheets such as enhancing mineralization and reducing cytotoxicity in bone regeneration field have been reported. Thermo-responsive FHE hydrogel (mainly composed of oxidized hyaluronic acid (OHA), poly-ε-L-lysine (ε-EPL) and F127) also showed a desired outcome in skin regeneration due to its stability and antibacterial benefits. This study investigated the application of BP-FHE hydrogel in anterior cruciate ligament reconstruction (ACLR) both in in vitro and in vivo, and addressed its effects on tendon and bone healing. This BP-FHE hydrogel is expected to bring the benefits of both components (thermo-sensitivity, induced osteogenesis and easy delivery) to optimize the clinical application of ACLR and enhance the recovery. Our in vitro results confirmed the potential role of BP-FHE via significantly increased rBMSC attachment, proliferation and osteogenic differentiation with ARS and PCR analysis. Moreover, In vivo results indicated that BP-FHE hydrogels can successfully optimize the recovery of ACLR through enhancing osteogenesis and improving the integration of tendon and bone interface. Further results of Biomechanical testing and Micro-CT analysis [bone tunnel area (mm2) and bone volume/total volume (%)] demonstrated that BP can indeed accelerate bone ingrowth. Additionally, histological staining (H&E, Masson and Safranin O/fast green) and immunohistochemical analysis (COL I, COL III and BMP-2) strongly supported the ability of BP to promote tendon-bone healing after ACLR in murine animal models.
RAB23 regulates musculoskeletal development and patterning
Authors: Hasan Md. Rakibul , Koskenranta Anna , Alakurtti Kirsi , Takatalo Maarit , Rice David P.
Published: February 2023

RAB23 is a small GTPase which functions at the plasma membrane to regulate growth factor signaling. Mutations in RAB23 cause Carpenter syndrome, a condition that affects normal organogenesis and patterning. In this study, we investigate the role of RAB23 in musculoskeletal development and show that it is required for patella bone formation and for the maintenance of tendon progenitors. The patella is the largest sesamoid bone in mammals and plays a critical role during movement by providing structural and mechanical support to the knee. Rab23−/− mice fail to form a patella and normal knee joint. The patella is formed from Sox9 and scleraxis (Scx) double-positive chondroprogenitor cells. We show that RAB23 is required for the specification of SOX9 and scleraxis double-positive patella chondroprogenitors during the formation of patella anlagen and the subsequent establishment of patellofemoral joint. We find that scleraxis and SOX9 expression are disrupted in Rab23−/− mice, and as a result, development of the quadriceps tendons, cruciate ligaments, patella tendons, and entheses is either abnormal or lost. TGFβ-BMP signaling is known to regulate patella initiation and patella progenitor differentiation and growth. We find that the expression of TGFβR2, BMPR1, BMP4, and pSmad are barely detectable in the future patella site and in the rudimentary tendons and ligaments around the patellofemoral joint in Rab23−/− mice. Also, we show that GLI1, SOX9, and scleraxis, which regulate entheses establishment and maturation, are weakly expressed in Rab23−/− mice. Further analysis of the skeletal phenotype of Rab23−/− mice showed a close resemblance to that of Tgfβ2−/− mice, highlighting a possible role for RAB23 in regulating TGFβ superfamily signaling.
Access to carbon nanofiber composite hydrated cobalt phosphate nanostructure as an efficient catalyst for the hydrogen evolution reaction
Authors: Ahmed Imtiaz , Biswas Rathindranath , Sharma Rohit , Burman Vishal , Haldar Krishna Kanta
Published: February 2023

Attractive technology for producing sustainable hydrogen with water electrolyzers was foreseen as one of the most promising ways to meet the increasing demands of renewable resources and electricity storage. Mainly used for the efficient generation of H2, water electrolysis involving hydrogen evolution reactions (HERs) depends on efficient and affordable electrocatalysts. Hydrogen is an effective fuel that can be produced by splitting water. Hence, the search for highly efficient HER catalysts is a major challenge as efficient hydrogen evolution catalysts are sought to replace catalysts such as platinum. Here, we describe a low-cost and highly effective electrocatalyst for the proper incorporation of the HER electrocatalyst with low overpotential, effective charge transfer kinetics, low Tafel slope, and good durability. By using a simple hydrothermal approach to produce Co3(PO4)2.8H2O/CNF, it is possible to attach Co3(PO4)2.8H2O to the surface of carbon nanofibers (CNFs), which also exhibit remarkable HER activity at an overpotential of 133 mV and produce a current density of 10 mA/cm2 and a 48 mV/decade for the Tafel slope. Large electrochemical surface areas and easy charge transfer from Co3(PO4)2.8H2O to the electrode through conductive Co3(PO4)2.8H2O/CNF composites are the reasons for the improved performance of Co3(PO4)2.8H2O/CNF.
Open curriculum for teaching digital accessibility
Authors: Gay Greg
Published: February 2023

In Ontario, Canada, universities are obligated under the Accessibility for Ontarians with Disabilities Act (AODA) to ensure that people with disabilities do not face barriers to education, and they are free from barriers in society more broadly. Those who produce online curriculum for postsecondary education in the province need at least a basic understanding of digital accessibility, and for some roles, like software or web developers, a level of expertise is required. However, finding people with the right knowledge, skills, and attitude can be difficult. This problem can be attributed to the fact that until recently digital accessibility skills have received little attention in post-secondary education. To address the issue, in 2015, with support from the Government of Ontario, we began several projects to develop digital accessibility curriculum. These efforts created a series of free Massive Open Online Courses (MOOCs) aimed at teaching digital accessibility skills to audiences ranging from office support workers, to managers, to developers, to digital accessibility specialists. The MOOCs ran between 2016 and 2019 and served more than 5000 participants, with more than 600 successfully completing the requirements for the digital badge(s) awarded. Following the MOOCs project, the content of the courses was converted into Open Educational Resources (OERs) that could be used as textbooks to support the introduction of digital accessibility topics over a range of subject areas, with encouragement for others to reuse the content to add accessibility related topics into their teaching. The OERs were downloaded more than 10,000 times between late 2020 and late 2022 and provided the base content for four open courses developed through OERU. In this article the pedagogy and curriculum for this digital accessibility training are described.
Early vascular healing after neXt-generation drug-eluting stent implantation in Patients with non-ST Elevation acute Coronary syndrome based on optical coherence Tomography guidance and evaluation (EXPECT): study protocol for a randomized controlled trial
Authors: Zhu Yong-Xiang , Liang Li , Parasa Ramya , Li Zheng , Li Qian , Chang Shang , Ma Wen-Rui , Feng Si-Li , Wang Yang , Xu Bo , Bourantas Christos V. , Zhang Yao-Jun
Published: February 2023

Background

There is limited evidence about vessel wall healing response following implantation of next-generation drug-eluting stents (DES) in patients admitted with a non-ST elevation acute coronary syndrome (NSTE-ACS). Cumulative data indicate that optical coherence tomography (OCT) imaging can optimize percutaneous coronary intervention results and expedite stent endothelialization in the general population but there is lack of data in NSTE-ACS patients.

Methods

The EXPECT study is an investigator-initiated, prospective, randomized trial to assess early vascular healing response following next-generation DES implantation in patients admitted with NSTE-ACS based on OCT guidance and evaluation. Sixty patients are randomized at 1:1:1 ratio to OCT-guided percutaneous coronary intervention (PCI) with 3-month follow-up OCT imaging (O3 group, n = 20), to angiography-guided PCI with 3-month follow-up OCT imaging (A3 group, n = 20) and to angiography-guided PCI with 6-month follow-up OCT imaging (A6 group, n = 20). The primary endpoint of the study is stent strut coverage rate at 3- or 6- month follow-up in the studied groups. The secondary endpoints of the study include OCT imaging endpoints, clinical endpoints, and molecular biology endpoints at the different time points. The clinical endpoints comprised of major cardiovascular adverse events and individual components. The molecular biology endpoints comprised of lipid levels and the levels of inflammatory indicators.

Discussion

The findings of the EXPECT study are anticipated to provide novel insights into vessel wall healing in NSTE-ACS population following implantation of next-generation DES, underscore the value of OCT imaging in expediting strut coverage in this setting, and explore the potential of an early discontinuation of dual antiplatelet therapy (DAPT) in this population.

Clinical Trial Registration:

ClinicalTrials.gov, NCT04375319.
New therapeutic approach for tricuspid regurgitation: Transcatheter tricuspid valve replacement or repair
Authors: Blusztein David I. , Hahn Rebecca T.
Published: February 2023

The tricuspid valve is a complex structure with normal function dependent on the leaflet morphology, right atrial and annular dynamics, and right ventricular and chordal support. Thus, the pathophysiology of tricuspid regurgitation (TR) is equally complex and current medical and surgical management options are limited. Transcatheter devices are currently being investigated as possible treatment options with lower morbidity and mortality than open surgical procedures. These devices can be divided by their implant location/mechanism of action: leaflet approximation devices, annuloplasty devices, orthotopic valve implants, and heterotopic valve implants. The current review will discuss each class of transcatheter device therapy, and further delve into the current understanding of who and when to treat. Finally, we will include a brief discussion of the future of device and surgical therapy trials for TR and the remaining questions to answer about this complex disease process.
Can healthcare apps and smart speakers improve the health behavior and depression of older adults? A quasi-experimental study
Authors: Kim Dasom
Published: February 2023

Purpose

This study identified the effects of applying information and communication technologies (ICT) to the health management of older adults aged 65 or older.

Methods

Older adults registered at public health centers were provided with the health management app “Health Today” and a smart speaker for 6 months to perform assigned healthcare missions. The program was conducted for 6 months by dividing participants into two groups: one that received both the health management app and the smart speaker, and another that used only the health management app. Depression, self-efficacy, number of days of moderate-intensity exercise, relative grip strength, balance tests, and five-times-sit-to-stand tests were measured during the pre- and post-evaluation.

Results

Both groups showed a positive health status and behavioral changes at post-evaluation. However, no reduced depression was observed due to communication and music listening functions in the group that was additionally provided smart speakers.

Conclusion

ICT use in healthcare can be beneficial for older adults. However, whether these devices meet the purpose of the national health project must be determined, and an effect evaluation must be undertaken prior to providing these ICT devices for the health management of older adults in the public domain.
Hydrogeochemical characteristics and the genesis of the No. Lu 32 well in the Jiaodong Peninsula, China
Authors: Du Guilin , Zhai Bin , Su Shujuan , Sui Lailun , Chang Xiangchun , Ren Hongwei , Sun Maiyu , Wang Lili
Published: February 2023

The No. Lu 32 well is a seismic observation well situated on the easternmost tip of the Penglai–Weihai fault zone in the Jiaodong Peninsula. It is necessary to reveal the genetic mechanism of the water in this well for earthquake forecasting along the Penglai–Weihai fault zone. Water samples were collected from the No. Lu 32 well, neighboring wells, and seawater to measure the hydrochemical composition and main hydrogen and oxygen isotopic compositions. The water type of the No. Lu 32 well is Cl–Na, which may be due to the influence of seawater intrusion. Hydrogen and oxygen isotopes indicate that the No. Lu 32 well and adjacent wells are mainly influenced by meteoric water, that the high salinity in the water is mainly from the mixing of modern seawater, and that the proportion of seawater there is approximately 5%. Observation of water temperature data in the No. Lu 32 well over several years shows regular annual variations. This comprehensive study shows that the well is greatly affected by seawater backflow infiltration and shallow water. The results of this paper provide an important reference for exploring the hydrogeochemical characteristics and genesis of wells in other coastal zones.
A comparative study of Texas–Mexico border vs. non-border students’ achievement on high-stakes state test: A propensity score matching method
Authors: Wang Zhuoying , Tang Shifang , Luo Feng
Published: February 2023

Texas–Mexico border region is a unique place where two countries and culture connected. We sought to investigate border school district students’ academic performance as measured by Texas standardized test: the State of Texas Assessments of Academic Readiness (STAAR). To do so, we first used propensity score matching (PSM) techniques to analyze data collected from a public database: Texas Assessment Management System (TAMS). Specifically, we provided a PSM analysis of non-border and border school districts regarding their demographic characteristics [i.e., identified as a rural district, percentage of economically disadvantaged (ED) students, percentage of English learners (ELs), mobility rate, instructional hours, principal experience, teacher experience, teacher–student ratio, and teacher turnover rate]. Then, multiple regression analyses were conducted to compare Texas border and non-border school students’ reading, math, and science achievements, respectively, based on a matching sample with control for demographic variables. The results of the current study indicate that no significant difference was found between border and non-border school districts, regarding students’ academic performance in reading, math, and science, when districts were matched and demographic characteristics were controlled. We further found that demographic variables, such as percent of ED students, principal experience, and teacher turnover rate, significantly impact students’ academic achievement. Such findings have suggested that the achievement gap between border and non-border districts can be closed if extra support can be provided to ED students, and funding could be allocated in border districts to maintain experienced principals and teachers.
Emotional regulation, attachment style, and assertiveness as determinants of well-being in emerging adults
Authors: Plantade-Gipch Anne , Bruno Julien , Strub Lionel , Bouvard Martine , Martin-Krumm Charles
Published: February 2023

Introduction

The emerging adult stage of life is a time of many positive changes, as well as stress and uncertainty. Certain psychological characteristics - such as emotional regulation, attachment style, or assertiveness – could help these adults thrive and maintain positive mental health. This study aimed to explore the influence of these variables on the well-being of emerging adults.

Methods

The sample included 360 French emerging adults, with a mean age of 21.3 years. Well-being was assessed with the Mental Health Continuum, emotional regulation with the Emotional Regulation Difficulties Scale, assertiveness with the Assertiveness Scale, and attachment styles with the Relationship Scales Questionnaire.

Results

Results showed that judgment toward one’s own emotional experience and shyness (as part of assertiveness) predicted emerging adults’ well-being. This study also highlighted the role of substance use and experiences of violence on emerging adults’ emotional regulation and well-being.

Discussion

Results support the importance of in-person and distance education and prevention to support emerging adults’ well-being, especially in higher education institutions and in times of the COVID pandemic.