bluuebunny/crossref_metadata_2025 huggingface dataset:
The relationship between inflammatory markers from blood routine test and colorectal polyps
Authors: Yin Wen , Huang Yaochan , Gao Feng , Ye Xiaoyan , Zhang Yuqi , Wu Congye , Yuan Jie
Published: December 2023

Objective: The aim of this study was to investigate the relationship betweeninflammatory markers and colorectal polyps.
Methods:The inflammatory markers included neutrophils to lymphocytes ratio (NLR), platelets to lymphocytes ratio (PLR), lymphocytes to monocytes ratio (LMR), and red blood cell distribution width (RDW). A total of 4963 patientsunderwent gastrointestinal endoscopy were retrospectively analyzed. The inflammation markers were compared between the polyp group and the normal group. The pathological types, numbers, and diameter of polyps were analyzed between high and low inflammatory marker groups.
Results: The NLR, PLR, and RDW values in the polyp group were higher when compared to those in the normal group, while the LMR value was lower (P <0.05). The incidence rates of adenomas were higher in the high NLR and high RDW groups when compared to the low NLR and low RDW groups. Similarly, the incidence rates of adenomas were higher in the low LMR group compared to the high LMR group (P <0.05). However, there was no significant correlationbetween the level of inflammatory markers and the number or diameter of polyps (P >0.05).
Conclusion: There is a correlation between inflammatory markers and colorectal polyps, particularly in patients with adenoma as opposed to non-adenoma patients. However, there is no clear correlation between the diameter and number of polyps and these inflammatory markers.
Dynamics and Analysis of Dengue Epidemics: A Fractional Order SIR Model with Next-Generation Matrix Methodology
Authors: Alfalqi Suleman , Niazi Azmat Ullah Khan , Ramay Easha , Ahmed Bilal , Alhagyan Mohammed
Published: December 2023

One of the major infectious diseases in the world is dengue. Dengue fever, a mosquito-borne viral infection, continues to pose a significant public health threat in tropical and subtropical countries. In this article, we analyze the susceptible-infected-recuperated (SIR) model-based fractional order differential equation of the dengue epidemic system and we analyze of fractional model for the dengue transmission utilizing the new term Human hospitalized. The next-generation matrix methodology is used to obtain the threshold quantity value $R_{0}$, which is comparable to the essential reproduction value. In the case of constant controls, we evaluate the presence and consistency of the disease-free and infectious equilibrium simulation alternatives. The disease-free equilibrium (DFE) point and the endemic equilibrium point's local stability are discussed. We were able to determine that DFE is locally asymptotically stable when $R_{0}<1$ and unstable when $R_{0}>1$ by applying the linearization theorem. Numerical simulations are conducted to validate the proposed model against real-world dengue data. For various parameter values of the derivative $\alpha$ order, numerical simulations are provided. The proposed model is validated using published every year (390 millions) dengue cases are reported in world wide. The presented model, it is noted, offers a more accurate means of analyzing the dynamics of the disease dengue.
2010 MSC: 26A33, 34K37.
Moral Sensitivity and Beliefs in Medical Students during the COVID-19 Pandemic
Authors: Farahani Mohammad Shahrabi , Daneshfard Babak , Johari Zahra , Yarmohammadi Hossein , Soltanipur Masood , Iranzadasl Maryam
Published: December 2023

Background
Apart from healthcare concerns, the COVID-19 pandemic has also brought up ethical challenges. This study aimed to shed light on one of the ethical questions regarding medical students' responsibilities during the current pandemic.
Methods
An online anonymous questionnaire was applied to ask Iranian stagers and interns about their demographics and beliefs toward ethical responsibilities during the pandemic. Data were gathered in two phases; before and after COVID-19 vaccination. The SPSS software was used for statistical analysis.
Results
At the end of the study, 95 and 264 students participated in the first and second phases, respectively. The mean moral sensitivity score was 38.11 ± 4.88 in the first phase and 35.39 ± 4.9 in the second phase (p-value < 0.001). Among the participating students, 60 (63.2%) believed that it is their ethical responsibility to contribute to patient care at the hospital. The majority of students believed it was their ethical responsibility to contribute to the management of patients during the pandemic at both phases (63% and 71%, p-value = 0.15). In the multivariate analysis, age and ethical responsibility were related to moral sensitivity in the first phase. Age, sex, being worried about getting COVID-19, and ethical responsibility had a relationship with moral sensitivity score.
Conclusion
The moral sensitivity of medical students had a relationship with their belief in ethical responsibility. To improve moral reasoning and moral motivation, the adaptation of the medical ethics course with new challenges related to the COVID-19 pandemic and emphasizing their usefulness at the hospital during the crisis could be helpful.
Autonomous docking manoeuvre Testing in the framework of the ERMES experiment
Authors: Bortotto Alessandro , Agli Giuliano Degli , Pozzato Nicola , Dignani Mattia , Favotto Federico , Mattiazzi Fabio , Mihailovic Miroljub , Branz Francesco , Olivieri Lorenzo , Caon Alex , Lion Luca , Basana Federico , Francesconi Alessandro
Published: December 2023

The advent of the recent ”New Space Economy” allowed access to low-Earth orbits to a rising number of commercial enterprises, non-profit groups, and educational institutions. As a consequence, the global small satellite market has grown substantially, since they have proven to be a suitable low-cost alternative for several space missions and technological demonstrations. In this context, proximity operation systems for autonomous small satellites are continuously under investigation, due to their effectiveness for many applications.
Experimental Rendezvous in Microgravity Environment Study (ERMES) is a student project, which aimed at testing an autonomous docking manoeuvre between two free-flying CubeSats mock-ups in a reduced gravity environment. The manoeuvre is characterized by an active Chaser and cooperative Target approach. In particular, the Chaser is equipped with a cold gas propulsive system based on expendable CO2 cartridges for 3-dimensional manoeuvring, whereas the Target has a set of reaction wheels for attitude control. The magnetic post-manoeuvre connection is achieved thanks to a dedicated miniaturized docking interface. Moreover, the reduced gravity conditions have been achieved by participating in the European Space Agency (ESA) 79th Parabolic Flight Campaign thanks to the selection in the ESA Fly Your Thesis! Programme 2022 (FYT).
This article depicts an overview of the ERMES experiment, discussing its core objective and key design solutions, up to analyzing the results of the tests carried out during the aforementioned Parabolic Flight Campaign. Relevant focus is dedicated to the investigation of the functionality and effectiveness of the Guidance Navigation and Control (GNC) system of the Chaser.
AI-Driven Intelligent Transportation Systems in the Age of 5G/6G Networks
Authors: Musa Usman Ibrahim , Gupta Sakshi , Mensah Queen Emmanuella
Published: December 2023

A multitude of challenges confront Intelligent Transport Systems (ITS) due to the rapid growth in demand for wireless connectivity, the more diverse and het- erogeneous nature of 5G network traffic, and the likelihood of 6G being even more complicated. This research offers an AI-driven approach created especially for ITS in the context of 5G/6G networks to overcome these challenges. The goal of the research is to create a customised prediction model for traffic forecasting in ITS by analysing the efficiency of the 5G/6G network. Our proposed model, known as Refinished Long Short-Term Memory (RLSTM), employs AI methods to produce precise predictions. It dynamically adjusts hidden units and layers for enhanced accuracy. To tackle 5G traffic’s unpredictability, the model utilizes seasonal time differences to stabilize the output sequence from the original time series. Exper- imental analyses show that the RLSTM algorithm significantly improves the 5G traffic prediction performance when compared to conventional methods. This AI-driven concept offers a potentially effective way to address problems with Intelligent Transport Systems in the context of 5G networks. Its capacity for providing precise predictions enables better decision-making for efficient traffic management.
Association between CTLA-4 +49A/G (rs231775) polymorphism and the risk of autoimmune thyroid diseases: A systematic review and meta-analysis
Authors: Li Xin , Qi Huilan , Wang Chunlan , Chen Yanlin , Li Qian , Xie Hailin , Li Jinmei , Wang Fang
Published: December 2023

Background
Previous studies have investigated the association between CTLA-4 + rs23177549A/G gene polymorphism and the risk of autoimmune thyroid disease (AITD), but there are some conflicting findings among those studies. This study aimed to summarize relevant evidence available regarding the association of CTLA-4 + rs23177549A/G gene polymorphism and AITD.
Materials and Methods
An extensive literature search was conducted in PubMed, EMBASE, and Web of Science for pertinent papers published up until January 24th, 2022. We included all the case-control studies that investigatedthe association between the rs23177549A/G gene polymorphism and susceptibility to AITD.
Results
46 case-control studies met the inclusion criteria and were included in this analysis in total. Our results indicated that CTLA-4 + rs23177549A/G polymorphism was not associated with increased susceptibility to AITD. No significant association with CTLA-4 + rs231775 49A/G polymorphism was detected for the risk of Graves' disease and HT. Subgroup analysis by race showed significant association in Asians, except in the recessive genetic model.
Conclusion
There was no significant association between the CTLA-4 + rs2317749A/G polymorphism and the risk of autoimmune thyroid diseases.
Has heterogeneous environmental regulation promoted a cleaner transition in China's energy consumption structure?
Authors: Chang Hongwang
Published: December 2023

At present, the world energy resources map is undergoing profound changes. Global energy technology is brewing a profound change, and all countries are committed to the transition to green and low-carbon energy. This paper refers to the study of Acemoglu (2012) and discusses the impact of heterogeneous environmental regulations on the energy consumption structure at the theoretical level by building a two-sector model that includes both clean energy and traditional energy outputs. Then, based on China's provincial panel data from 2007 to 2020, we examine the impact of heterogeneous environmental regulations on the structure of energy consumption using fixed effects and double difference methods. It is found that the double substitution and decarbonisation effects of command-and-control environmental regulations on energy are not significant due to the influence of regional resource endowment and the level of regional economic development. However, market-incentivised environmental regulation significantly reduces the proportion of coal consumption, strengthens the substitution effect of clean energy for nonclean energy, and significantly improves the decarbonisation index of the energy consumption structure. This paper provides more theoretical support and empirical evidence for the government to use heterogeneous environmental regulations to promote energy consumption structure transformation.
Intelligent Detection Method of Microparticle Virus in Silk-worm Based on YOLOv8 Improved Algorithm
Authors: Zhang Yinguang , Su Jianhuan , Wang Teng , Xu Chuan , Yu Ao
Published: December 2023

The presence of microparticle viruses seriously affects the quality of silkworm seed for domestic sericulture, so it is important to exclude them from detection in silkworm seed production. The traditional methods for detecting microparticle viruses in silkworms are manual microscopic observation, molecular biology, immunological approach, etc., which are cumbersome steps and cannot achieve intelligent detection and batch real-time detection. The YOLOv8 algorithm is used in this paper to address this problem. Firstly, NAM attention is introduced in the original algorithm's Backbone part. Therefore, the model can extract more generic information about features. Secondly, ODConv is used to replace Conv in the Head part of the original algorithm to enhance the model's ability to identify microparticle viruses. Finally, NWD-LOSS is used to modify the CIOU loss of the original algorithm to obtain a more accurate prediction box. The experiments indicate that the NN-YOLOv8 model is more accurate in detecting silkworm microparticle disease than mainstream detection algorithms. For a single image, the average detection time is 22.6 milliseconds, it has better prospects for future applications.
Aluminum-Doping Enhances the Photocatalytic Activity of CdFe2O4 Nanoparticles for Effective Removal of the Herbicide Atrazine
Authors: Yasar Muhammad , KHAN ZAHRA
Published: December 2023

The successful synthesis of aluminum-doped cadmium ferrite Cd1AlxFe2 − XO4 (x = 0,0.2) via a facile sol-gel technique. Characterized by XRD, FTIR, SEM, EDX, DRS, Resistivity, and BET, these nanoparticles exhibit enhanced visible-light photocatalytic activity towards atrazine removal in water. A clear peak at (311) verified the presence of a single-phase FFC spinel ferrite structure, with Al doping influencing surface area (32.53 vs 14.43 m2/g for undoped), band gap (2.6 eV vs. 2.8 eV), and morphology. FTIR analysis reveals two main absorption peaks at 537 cm− 1 (ν1) and 453 cm− 1 (ν2), corresponding to the intrinsic stretching vibrations of tetrahedral and octahedral sites, respectively. Aluminum doping shifts these peaks 453 cm− 1 (ν2) TO 449 and 537 cm− 1 (ν1) TO 531 cm− 1, indicating changes in bond lengths and angles within the crystal structure. SEM reveals small, well-defined Al-doped particles and diminutive, smooth undoped counterparts. The existence of Cd, Fe, Al, and O elements is confirmed by EDX analysis. Hydroxyl radicals (OH•) are identified as the primary atrazine degradation species via scavenger analysis. Al doping significantly enhances atrazine removal (97% vs. 72.46% with undoped), attributed to the reduced band gap facilitating visible light absorption The first-order plot fits the data better than the second-order plot, as evidenced by the higher R2 value (0.995 vs. 0.840). Furthermore, the Al-doped nanoparticles demonstrate excellent stability over five reuse cycles, highlighting their potential for sustainable water purification. Their eco-friendly composition and cost-effective synthesis suggest promising applicability in environmental remediation technologies.
Short Video Recommendation through Multimodal Feature Fusion with Attention Mechanism
Authors: Langlois Jaxon , Dupuis Callum , St-Pierre Nikolai , Hollis Maeve
Published: December 2023

To address the issue of information overload, recommendation systems have emerged. These systems analyze user attributes and historical behavior to gain profound insights into user needs, thereby filtering and selecting content that aligns with those needs. Challenges in Applying Traditional Recommendation Methods to Video Recommendation: Addressing issues such as cold start problems, sparsity, and over-specialization when traditional recommendation methods are applied to video recommendation. Different Recommendation Modes: This includes sorting-based video recommendations, recommendations based on video summaries, and multi-modal or cross-modal recommendations. This paper primarily focuses on attention-based feature representation models at the feature level, learning features from different perspectives. Simultaneously, addressing the specific scenario of short video recommendations, where current approaches often rely on user preferences, user behavior, and other metadata for recommendations, neglecting the content of the short videos themselves, leading to a severe cold start problem and resulting in the neglect of most short videos. Hence, building upon efficient feature representation, this paper considers short video content and social relationships to explore user preferences from multimodal video content and social connections, enhancing the model's predictive accuracy.
Social Interactions and Everyday Life of Post-War Village Residents in the Oral History Materials of Posullya
Authors: Korol Vitaliy , Porfilova Maryna
Published: December 2023

The publication is dedicated to the study of social interactions, everyday life, leisure, and daily life of a post-war village by studying the oral historical memory of the population of the former Nedryhail district of the Sumy region.
The work presents transcripts of interviews with elderly people - ordinary direct participants and witnesses of events. Chronologically, the study is focused on the period of the first postwar twenty years (the second half of the 1940s – the first half of the 1960s), however, the features of the resulting narrative involve constant deviations from these time limits and excursions to earlier and later events.
The memories presented as vivid illustrations make it possible to better understand the essence of the historical processes of the modern era and can be used as a source for writing further scientific works, to make future research both in the geographical boundaries of Ukraine and of a local history much more relevant.
Interconnection between bank capitalization and macroeconomic stability in the countries of South-West Asia
Authors: Ashurbayli-Huseynova Nigar , Garmidarova Yevgeniya
Published: December 2023

The paper aims to define the specifics of the mutual interconnection between bank capitalization and indicators of macroeconomic stability. This is achieved by the following methods: grouping, analysis and synthesis, analysis of descriptive statistics, and canonical correlation analysis. The study was carried out based on eight bank capitalization indicators and five macroeconomic stability indicators in seventeen South-West Asian countries from 2010 to 2020. The information base of the research is the dataset from the World Bank. The selected list of indicators is determined by the availability of statistical information for the countries participating in the study. It was found that there is a close canonical correlation between the level of bank capitalization and the macroeconomic stability of the countries under investigation – 0.97 (2010) and 0.99 (2020). The variation of the investigated indicators of macroeconomic stability (68.95% (2010) and 70.64% (2020)) is determined by the change in bank capitalization indicators. On the other hand, the difference in macroeconomic stability indicators of countries by 48.66% (2010) and 42.79% (2020) is due to changes in bank capitalization indicators. Four indicators exert the most significant favorable influence on the level of bank capitalization: Bank return on assets – 0.303 (2010) and 13.033 (2020), Bank return on equity – 0.446 (2010) and 13.387 (2020), Bank regulatory capital to risk-weighted assets – 0.812 (2010), and Bank deposits to GDP – 1.580 (2020). The macroeconomic stability of countries is determined by two indicators: GNI – 3.311 (2010) and 3.461 (2020); GDP – 4.748 (2010) and 4.672 (2020).
The relationship between organizational characteristics and the quality of local government financial statements
Authors: Zabedah Saidin Siti , Ismail Engku Ali Engku
Published: December 2023

This study investigates the relationship between organizational characteristics and the quality of financial statements in Malaysian local government. Organizational characteristics, including status, size, financial stability, tax revenue collection efficiency, and level of competence, were examined to discern their impact on mandatory information disclosure in local government financial statements. Data were collected from 71 local governments in Peninsular Malaysia, representing nearly 74% of the total population, using a combination of secondary data from audited financial reports and official documents, as well as structured questionnaires. The results indicate that tax revenue collection efficiency and the level of competence had a significant positive relationship with financial statement quality. Conversely, organizational characteristics related to status, size, and financial stability did not significantly impact financial statement quality. This implies the greater significance of human resources, precisely tax revenue collection efficiency and account officers’ competence, in shaping local government financial statement quality in Malaysia. These findings support the stewardship theory, confirming the connection between specific organizational characteristics and financial statement quality. However, limitations include relying solely on secondary data and facing certain data collection constraints. Future research can enhance these findings by exploring additional factors through in-depth qualitative or case studies.
Grass awn in the urinary bladder of a 5-months old mixed-breed dog – a case report
Authors: TURLEWICZ-PODBIELSKA HANNA , PODBIELSKI KONSTANTY , MICHALSKA KAROLINA , WOJCIECHOWSKI JAROSŁAW
Published: December 2023

Grass awn foreign body-related disease is common in dogs throughout Poland, typically affecting the ears and subcutaneous tissue, but the presence of grass awns in the urinary bladder is a rare pathology in veterinary medicine. The diagnosis of foreign bodies in the urinary tract is challenging because their signs overlap with those of urinary tract infections. Hence, patients with grass awns in the urethra or urinary bladder can easily be misdiagnosed and mistreated. It is worth considering the potential presence of a plant foreign body in the urinary tract in the case of sudden hematuria and abdominal discomfort, especially in the spring and summer. Quick diagnosis and surgery treatment are essential to protect the patient from severe complications. The purpose of this report is to present the diagnosis and treatment of a dog with hematuria and abdominal discomfort which was diagnosed with a foreign body (a grass awn) in the urinary bladder.
The Second Omega Index
Authors: Ozalan Nurten Urlu , Cevik Ahmet Sinan , Cangul Ismail Naci
Published: December 2023

Background:

The omega index has been recently introduced to identify a variety of
topological and combinatorial aspects of a graph with a new viewpoint. As a continuing study
of the omega index, by considering the incidence of edges and vertices to the adjacency of the
vertices, in this paper, we have introduced the second omega index Ω2 and then computed it
over some well-known graph classes.

Methods:

Many combinatorial counting methods have been utilized in the proofs. The edge
partition is frequently used throughout the work. Naturally, some graph theoretical lemmas are
also used.

Results:

In particular, trees having the smallest and largest Ω2 have been constructed. Finally,
the second omega index of some derived graphs, such as line graphs, subdivision graphs, and
vertex-semitotal graphs, has been presented.

Conclusion:

Omega invariant has already been explored in many papers. It has been defined
in terms of vertex degrees. Vertices correspond to the atoms in a molecule and a calculation,
which only depends on the atomic parameters, is not even comparable with a calculation containing both atoms and chemical bonds between them. With this idea in mind, we have evaluated some mathematical properties of the second omega index, which has great potential in
chemical applications related to the number of cycles in the molecular graph.
Confidence Interval: Advantages, Disadvantages and the Dilemma of
Interpretation
Authors: Sharma Pramod K. , Yadav Mamta
Published: December 2023

Confidence interval (CI) is one of the important reporting tools for research data as it
not only provides valuable information about the effect size along with its width but also
possible clinical significance. Unfortunately, this approach is not being utilized to its fullest
extent. Determining point estimate always includes an element of uncertainty due to associated
sampling error. A confidence interval may be an appropriate tool to measure this uncertainty.
Further, the P value does not convey information about the magnitude of an effect and the error
associated with it. Thus, in an ideal situation effect size should preferably be associated with a
confidence interval to assess precision. Not only does CI let us assess likely effects but also
decides whether the intervention applied could have clinical utility. In contrast, the P-value limits
our option to either reject any differences that are not significant or accept those that are.
However, confidence intervals are commonly misinterpreted. It is imperative to understand that
the CI is not the range of effects that 95% of patients in the population exhibit. Moreover, it
would also be erroneous to say that there is a 95% probability that the CI includes the true
population effect. Interpretation is usually based on the context in which the confidence interval
is being looked at. From a utility point of view and like other statistical tools confidence interval
approach does have several advantages as well as disadvantages and is far beyond being a
perfect statistical tool.
New Record of Two Medicinal Plants, Exallage Auricularia and Gomphostemma
Ovatum, from Ultapani Reserve Forest, Northeast India
Authors: Baglary Gouri Rani , Basumatary Twinkle , Islary Anuck , Kumar Santosh
Published: December 2023

Aim::

This report discusses two medicinal plants, namely Exallage auricularia (L.) Bremek from Rubiaceae family and Gomphostemma ovatum Wall
from Lamiaceae family from Ultapani Reserve Forest of Bodoland Territorial Region (BTR) of Assam, India, are recorded, described, and
identified based on their morphological characters, taxonomical notes, phenology, and field photos along with map of distribution.

Methods::

The local Bodo-trib of Assam used leaf paste of E. auricularia to cure jaundice and piles and G. ovatum for treatment of different ailments like flu,
cough, cold, skin irritations, symptoms of indigestion, jaundice, etc.

Results::

Inflorescence - verticillaster inflorescence in leaf axil, 3 to many flowers, 2 to 5 cm long. Flowers are born in opposite cymes, subtended by bracts,
easily indistinguishable from leaves, and the arrangement of flowers is congested or lax. Bracts - leaf-like small cluster, subtending cyme,
involucral bracts, stellate hairs, large bracteoles exceeding the calyx.

Conclusion::

G. ovatum is a perennial plant that can grow up to around 1.5 m tall and has tuber-like roots with infrequent node-level rooting.
Formulation and Evaluation of Gel Containing Nigella sativa Seed Extract
Loaded Transferosomes for Effective Treatment of Psoriasis
Authors: Sahu Ravish , Sharma Neeraj Kumar , Kumar Ashok , Sahu Sanjeev Kumar
Published: December 2023

Background:

Psoriasis vulgaris is an autoimmune associated skin disease causing
plaques or scales formation where the skin cells form quicker than in their typical life cycle. The
phenolic phytoconstituents reported in Nigella sativa are effective for the treatment of skin disorders. Transfersomes is an emerging nanoencapsulation drug delivery approach which can squeeze
themselves due to its elastic nature as an intact vesicle across narrow pores. It improves the potency
of topical formulations with higher permeation efficiencies compared to other vesicular drug delivery systems.

Objective:

This research work focused to prepare Nigella sativa or black seed extract loaded transfersomes as nanoformulation and further incorporating them in the gel system to give improved
therapeutic efficacy due to their self-regulating and self-optimizing capabilities.

Methods:

The phenolic content of Nigella sativa or black seed was extracted in ethanol and the
solvent was removed using a vacuum with suitable storage conditions at 22ºC. Transfersomes of
ethanol extract were prepared by thin layer hydration method and further incorporated into gel formulations. The ant-psoriasis activity of prepared gel formulation was performed with histopathology
study in the Imiquimod induced albino rat model.

Results:

A nanoformulation prepared with 0.85 mg lecithin and 0.10 mg tween 80 has the highest
entrapment efficiency. The entrapment efficiency, vesicle size, polydispersity index and zeta potential of optimized transferosomes batch were found to be 69.3 ± 2.6%, 178 ± 11 nm, 1.1 ± 0.2, -29.4
mV, respectively. Anti-psoriatic activity of N. sativa seed extract loaded transfersomes showed a
more significant reduction in thickness of the epidermis and less elongation of rete ridges with capillary loop dilation as compared to conventional gel formulation.

Conclusion:

We concluded that the Nigella sativa seed ethanolic extract loaded transfersomes gel
formulation showed significant ant-psoriasis activity in an albino rat model.
Editorial 30
Authors: Pattaro Amaral Fernanda
Published: December 2023

This volume of Pensamiento Americano has corruption as one of its featured articles. And, although it may seem wrong to say so, there is a need for us citizens to recognize the small corruptions we do on adaily basis. Obviously there are scales of corruption at various levels, but this corruption as a product of fetishistic materialism is part of our social history. Let us not be romantic about pointing out the macro corruption at institutional levels, for example, and avoid doing it by paying the police officer when we are going to withdraw a generous sum of money in Colombian banks. Because of the fear instilled in our minds by the newspapers almost daily, we accept to pay this agent to protect us until we arrive at our destination with that money taken out of the bank, with our lives intact. It is often said that "it is good to give something for the agent", although it is his function to provide us with this security, according to the internal communications of the banks. But... we pay for this agent to protect us and not to report us to the criminals. That, I am sorry to say, is how we are part of the gear of corruption. We can say we are corrupt when we accept the fruit basket from the student who lives in Sabanalarga, and needs to improve his grades - in this case, fruits are the bargaining chip.
Perspectiva dialógica de los derechos ante políticas neoliberales
Authors: Morris Bolaño Patricia Raquel , Hernández Palma Oona Isabel , Blanco Zúñiga Alejandro Luis , Bermejo Galán Jaime Camilo
Published: December 2023

Introducción: desde la entrada en vigor de la Constitución Política de 1991, coexisten en Colombia el postulado político Estado social de derecho, cuyo cometido fundamental radica en garantizar la dignidad de las personas a partir de un enfoque económico ysocial, y el modelo neoliberal que reduce el intervencionismo de Estado. Objetivo: en este sentido, el objetivo de este trabajo consistió en proponer una alternativa armonizadora de los referidos paradigmas, basada en la construcción democrática de los derechos, perspectiva que demanda la necesaria interacción entre gobierno y sociedad civil. Metodología: para este fin, el derrotero metodológico se fundamentó en el enfoque cualitativo, en un tipo de estudio explicativo y se utilizó la revisión bibliográfica como técnica de recolección de la información. Resultados: en relación con el resultado, la investigación develó la necesidad de lograr la concreción de los derechos, desde la amplia deliberación al interior de la sociedad, dado el reto de ejecutar programas de orden social, en el ámbito de concepciones neoliberales de la economía. Conclusión: a manera de conclusión, la tesis de este trabajo radicó en la conveniencia de acudir a la concertación como fórmula para viabilizar el avance y la justiciabilidad de los derechos en términos de civilidad, en el contexto de la variedad y conflictividad de intereses que coexisten al interior de la comunidad política.
Energiearmoede: een ruimtelijk verdelingsvraagstuk
Authors: Croon Tijn
Published: December 2023

In korte tijd heeft energiearmoede zich ontwikkeld tot een grote beleidsuitdaging in Nederland, maar toch bleek een gerichte aanpak van de energiecrisis onmogelijk. Kunnen een beter begrip en berekening van energiearmoede overheden helpen om beleid te voeren dat niet alleen efficiënter maar ook rechtvaardiger en duurzamer is?
De winnaars en de verliezers van de stedelijke wooncompetitie
Authors: van der Star Marieke
Published: December 2023

De verdichting van centraal gelegen delen van de stad blijft niet zonder ruimtelijke gevolgen en er lijkt een competitie om de meest aantrekkelijk gelegen woningen te ontstaan. Wie kan het zich dan eigenlijk nog veroorloven om in de meest centrale delen van de stad te wonen?
Radiation dermatitis: pathogenesis, diagnostics and classification. Review
Authors:   Institute of Theoretical and Experimental Biophysics of Russian Academy of Sciences, Sorokina S.S. , Karmanova E.E. ,   Institute of Theoretical and Experimental Biophysics of Russian Academy of Sciences, Popova N.R. ,   Institute of Theoretical and Experimental Biophysics of Russian Academy of Sciences
Published: December 2023

The radiotherapy has remained one of the most effective methods of treating cancer for several decades. Given the nonspecificity of ionizing radiation in relation to cancer cells, in the process of a target organ irradiating, it inevitably passes through the main human barrier organ – the skin, that often leads to such a long-term consequence as radiation dermatitis (RD). RD has been found to be a complication in more than 85% of patients undergoing standard radiotherapy. The pathogenesis of RD is not fully understood and, as a result, there is no “gold” standard for its prevention and treatment. To date, it has been possible to establish a number of features of the induction and development of RD, which explains the ineffectiveness of the available traditional methods of treating wounds and burns. The pathogenesis of RD is determined by the structural features of the skin, the significant contribution of ROS to radiation-induced inflammation, as well as a number of factors, which are usually divided into factors dependent on the patient and factors associated with the source of radiation. It has been shown that the pathogenesis of chronic RD and fibrosis has a number of distinctive features compared to acute RD, in particular, hypoxia is of particular importance during the progression of fibrosis, and chronic RD is accompanied by cell aging. To date, a modern classification of local radiation injuries by severity has been developed, based on developed clinical rating scales, which is important for proper treatment, management and monitoring in clinical practice. Among the methods for diagnosing RD, optical imaging methods occupy a special place, allowing non-invasive detection of various areas of skin damage. Despite significant advances in the study of RD, it is still a serious medical and social problem that significantly worsens the patient’s quality of life. Further study of the mechanisms of RD induction should lead to the development of new approaches in the prevention and treatment of RD.
Lymphocyte succinate and lactate dehydrogenase activity, induced ROS of neutrophils, and leukocyte DNA damage in the blood of mice irradiated with carbon ions
Authors:   Institute of Theoretical and Experimental Biophysics of Russian Academy of Sciences, Khunderyakova N.V. , Zaichkina S.I. ,   Institute of Theoretical and Experimental Biophysics of Russian Academy of Sciences, Dyukina A.R. ,   Institute of Theoretical and Experimental Biophysics of Russian Academy of Sciences, Mitroshina I.Yu. ,   Institute of Theoretical and Experimental Biophysics of Russian Academy of Sciences, Medvedeva V.P. ,   Institute of Theoretical and Experimental Biophysics of Russian Academy of Sciences, Koroleva M.A. ,   Institute of Theoretical and Experimental Biophysics of Russian Academy of Sciences, Kuznetsova E.A. ,   Institute of Theoretical and Experimental Biophysics of Russian Academy of Sciences
Published: December 2023

At the present time, the studies carried out to improve the radiotherapy of tumors using accelerated heavy ions are of great interest, since they give off the main energy at the end of the run at the Bragg peak, which increases the severity of radiation damage to the tumor and minimizes damage to surrounding healthy tissues. In this work, the levels of lymphocyte lactate dehydrogenase (LDH) and succinate dehydrogenase (SDH) activity, the ratio of LDH/SDH, induced reactive oxygen species (ROS) of neutrophils, and leukocytes DNA damage (%TDNA) in blood 1 day after accelerated carbon ions irradiation of mice with an energy of 450 MeV/nucleon in doses of 0.2-2 Gy in the Bragg peak were determined. Found: SDH activity increased at doses of 0.2-1 Gy and sharply decreased at a dose of 1.5 Gy in all mice. With a decrease in SDH activity, glycolysis (LDH activity) increased compensatory, which, apparently, is associated with the developing mitochondrial dysfunction of immune cells. The %TDNA of leukocytes increased depending on the dose and was accompanied by a decrease in the functional activity of neutrophils - the zymosan-induced ROS production decreased. Thus, against the background of an increased %TDNA and a decrease in SDH activity, glycolysis becomes of great importance. The applied methods are highly sensitive and can be used to detect individual differences in animals that are biological models in preclinical studies.
Comparative assessment of the distribution of 137Cs in the soil cover on the territory of Tajikistan
Authors:   Chemical, Biological, Radiological and Nuclear Safety and Security Agency of NAS of Tajikistan, Mirsaidov U.M. , Akhmedov M.Z. ,   Chemical, Biological, Radiological and Nuclear Safety and Security Agency of NAS of Tajikistan, Nazarov Kh.M. ,   Chemical, Biological, Radiological and Nuclear Safety and Security Agency of NAS of Tajikistan, Rakhimberdiev Sh.A. ,   Chemical, Biological, Radiological and Nuclear Safety and Security Agency of NAS of Tajikistan, Mukhamedova S.G. ,   I.M. Sechenov First Moscow State Medical University of Ministry of Health of the Russian Federation, Muminov S.V. ,   Chemical, Biological, Radiological and Nuclear Safety and Security Agency of NAS of Tajikistan
Published: December 2023

The article presents the results of a comparative assessment of the distribution of the technogenic radionuclide Cs-137 in the soil cover on the territory of the Republic of Tajikistan. It is noted that the accumulation of the 137Cs isotope in the territory depends on the terrain and soil type. At the foot of the mountains and in clay soils, a relatively high content of the Cs-137 isotope is observed compared to plains and sandy soils. The migration of radionuclide Cs-137 deep into the vertical is observed in the soils of sandy rock. It is shown that the values of the average specific activity of the Cs-137 isotope in the soil cover of Southern Tajikistan are 2.5 times lower than the average specific activities of the soils of Northern and Central Tajikistan. The highest values of specific soil activity of 17.0 Bq/kg were noted in the southeastern regions of Tajikistan. This circumstance is primarily due to the fact that precipitation and dust storms coming from the countries of South and Southeast Asia lead to the settling of particles, primarily on the slopes of the mountains. Thus, based on the analysis of the literature review in the direction under study and the results obtained, the authors revealed that the spatial distribution of Cs-137 radionuclide in the soil cover in the Republic of Tajikistan depends on the direction of the wind rose and the terrain. Analysis of the samples obtained allows us to conclude that the content of Cs-137 radionuclide is due to its long-range air transport.
Link between solar activity and forest fires from the standpoint of oncogenesis
Authors:   Far-East State Medical University, Pinaev S.K. , Chizhov A.Ya. ,   Patrice Lumumba Peoples' Friendship University of Russia,   Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency,   Medical Ecological Center "Mountain air XXI century", Pinaeva O.G. ,   Far-East State Medical University
Published: December 2023

The effect of solar radiation and forest fires smoke on cancer incidence has been studied and published in many research periodicals. Researchers found many indirect signs of the impact of the solar activity on the periodicity of landscape fires. The paper presents the research on the relationship between the solar activity and landscape fires, as well as the assessment of the role of natural events in carcinogenesis. The Pearson correlation analysis of the relationship between the dynamic series of the solar activity and the number of forest fires in the Khabarovsk Territory (1970-2019), in Russia and also separately in all its administrative territories (1992-2019) was analyzed in 11 iterations with a lag from 0 to 10 years. The reliable correlation was revealed in the Khabarovsk Territory (r=0.414; p=0.003) and in the whole Russia (r=0.472; p=0.011) with a lag of 7 years. The average bond strength in the regions of Russia in the 23rd cycle of the solar activity increased to a strong one (r=0.700±0.235), the average lag was 7.2±0.9 years. The role of cyclic changes in the solar radiation as the prerequisites for the landscape fires occurrence and the causes of fires was discussed. The discovery of an internal relation between the powerful environmental factors such as solar activity and forest fires is a significant supplement to the existing ideas about the nature of environmentally incused carcinogenesis.
Cytogenetic Effects of the Neonicotinoid Insecticides Nuprid 200 SL and Calypso 480 SC on Plant Model System
Authors: Stoyanov Ivan , Vasileva Penka , Staykova Teodora , Popova Teodora , Ivanova Evgeniya N.
Published: December 2023

Data from the present study indicate that the neonicotinoid insecticides Nuprid 200 SL (with the active substance imidacloprid) and Calypso 480 SC (with the active substance thiacloprid) reduce the mitotic activity by inhibiting cell division and increasing chromosomal aberrations in the cells of the root apical meristem of Allium cepa L. The tested solutions of pesticides cause a wide range of anomalies associated with disorders in forming the cell's division apparatus and the integrity of chromosomes. The comparative analysis of their mutagenic action shows a higher genotoxic potential of Calypso 480 SC. The established indices of chromosomal abnormalities for Calypso 480 SC and Nuprid 200 SL are 1.07 ± 0.38% and 0.70 ± 0.41% respectively. The mitosodepressant effect and a large number of chromosomal aberrations and mitotic abnormalities in Allium cepa cells when treated with Nuprid 200 SL and Calypso 480 SC are evidence of their high toxic potential and the significant risk of environmental pollution by their use in agriculture. Parts of this work was published in abstract form and presented as an oral presentation at the IV International Agricultural, Biological & Life Science conference, Edirne, Turkey, 2022 August 29-31, [1] and as a poster presentation at the 5th Balkan Scientific Conference on Biology, Plovdiv, Bulgaria, 2021 April 15-16 [2].
La Innovación Tecnológica y su Impacto en la Educación Superior Technological Innovation and its Impact on Higher Education
Authors: Rojas Sánchez Hernán Arturo , Pacheco Mendoza Silvia Rosa , Ribadeneira Zapata Carlos , Bayas Morejón Isidro Favián , Briceño Carrasquel Jorge Alexander , Gaibor Becerra José Luis , Hachi Pazmiño Michael Xavier , Guarnizo Ordóñez Jhoselyn Deyalit , Vega Romero Gustavo Javier
Published: December 2023

Los tiempos postpandémicos han demostrado que la investigación científica es el método que permite generar soluciones eficaces a problemas urgentes y complejos. La ciencia tiene el poder de mostrar el camino hacia un futuro sostenible, saludable y equitativo.

En este sentido, es importante la organización de eventos de difusión científica, puesto que son escenarios destinados al intercambio de ideas, presentación de avances y colaboración entre expertos de renombre de las diferentes disciplinas del conocimiento1.

La Universidad Estatal de Bolívar (UEB) desempeña un papel importante como ente generador de espacios de articulación entre las funciones sustantivas de docencia, investigación y vinculación. Todo ello, enfocado en presentar alternativas para la resolución de los problemas que aquejan a la sociedad en el marco de la pertinencia y los fines institucionales.

El Congreso Internacional de Ciencia, Tecnología, Innovación y Emprendimiento organizado por la Universidad Estatal de Bolívar, ha forjado su propia historia desde su primera edición, que fue ideado, organizado y llevado a cabo los días 10 y 11 de julio de 2013. Este acontecimiento se ha convertido en un hito dentro de la historia institucional y ha ido evolucionando conforme a la realidad dinámica del entorno social, académico y científico.
The histomorphological appearance of the testes in Alloxan-induced diabetic rabbits
Authors: Emran Hasanain , Habeeb Khyreia , Majeed Abeer
Published: December 2023

This study assessed the histomorphological changes in testicular tissues due to the experimental diabetes mellitus (DM) generated in rabbits with Alloxan. Twenty-four adult male rabbits were used and allocated randomly into two equal groups (n=12 of each). The first group served as a control group and received normal saline only. The second group (diabetic group) was injected with Alloxan at a 100mg/kg IP dose. The serum glucose level was estimated at (0 min), 3 days and then (1,2 and 3 months), by aspiration of a blood sample from the jugular vein mixed with anticoagulant (EDTA) to obtain serum. The testosterone hormone was assayed from the serum obtained by centrifugation of blood samples using a special kit. Testicular biopsies were harvested through surgical castration at (1,2, and 3 months) post-administration of Alloxan. Results displayed a marked increase in glucose levels in the diabetic group starting from day three till the end of the experiment, with high differences between the two groups.

Moreover, testosterone levels significantly decreased in the diabetic group compared to the control group. Our histomorphological examination confirmed that Alloxan leads to testicular damage in rabbits, represented by testicular atrophy, necrosis focusing in spermatogenic cells and separation of germinal epithelium. In conclusion, the injection of Alloxan succeeded in inducing (DM) with clear alteration in studied parameters.

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Key Words: Biochemical, Testicular Parameters, Alloxan, Rabbits.
Analisis de la actividad antioxidante y antimicrobiana del propóleo en la provincia Bolivar, Ecuador
Authors: Verdezoto Bósquez Alicia , Bayas-Morejón Favian , Monter Danilo , Cuenca García Yajaira , Lema Osorio Paul
Published: December 2023

El propóleo ha sido utilizado desde la antigüedad con fines medicinales, en la actualidad investigaciones han demostrado que el propóleo posee propiedades terapéuticas, antiinflamatorias, analgésicas y antisépticas, en tal sentido el objetivo de la presente investigación fue estudiar la actividad antioxidante y antimicrobiana del propóleo y su aplicación en la Agroindustria; Para lo cual, se determinó la actividad antioxidante a los propóleos procedentes de La Magdalena, San Miguel y La Chima, donde se identificó que el propóleo de La Chima posee mayor concentración de antioxidante a diluciones de 20 y 60 mg/mL, de igual manera, se determinó la actividad antimicrobiana frente a dos bacterias Gram positivas (Staphylococcus aureus, Bacillus) y dos bacterias Gram negativas (Escherichia coli, Salmonella spp), donde el propóleo de La Chima resultó ser más efectivo frente a Escherichia coli con halos de inhibición de 11,33 mm de diámetro. En conclusión, el propóleo de La Chima por ser el mejor tratamiento puede ser utilizado en la industria alimentaria como conservante natural.

Palabras clave: Propóleo; antioxidantes; antimicrobiano; colmena; bacterias; queso.