bluuebunny/crossref_metadata_2025 huggingface dataset:
A New Vision for the Design Process of Sustainable Urban Transportation
Authors: Hassan Tarek Mahmoud Yousry , Abdel Rahim Ahmed Abdel Hamid , Mohammed Shimaa Abdil Wahab
Published: May 2019

Nowadays, several new global trends have emerged, empathizing urban design dimension in the planning of transportation networks and keeping pace with urban, environmental and social development. These trends emerged into practice in many developed countries, aiming at achieving sustainability, improving the built environment, reducing and addressing the environmental impacts resulted from the misuse of local resources of the environment, improving public health and providing better quality of life. The patterns of these trends varied in both urban design and urban transportation. The frameworks of both urban design and urban transportation are closely linked to these modern trends, each of which relies on its own practical framework and is adapted to the local conditions according to the type and pattern of urbanization in which these trends originated. It is worth mentioning that the crosscutting points and the linkages between the two areas, urban design and urban transportation, clearly exist in a global methodological frameworks covering the design process in both fields. Hence, the research gap to be covered in this paper is creating a global framework that covers the design process in both fields.The objectives of urban design are closely related to the objectives of urban transportation. This makes it necessary to integrate these two fields in a clear and systematic framework that suits and meets the needs of the urban content of the Egyptian society. Taking into consideration the pace of development taking place in both areas at the global level, and the emergence of many attempts integrating both the theoretical and the operational level. The Egyptian society faces a large gap between the current situation of the Egyptian urbanization and the extent of the application of these modern global trends due to the absence of the importance of integrating urban design dimension in planning urban transportation in existing urban cities.In this context, the paper seeks to reach a comprehensive vision that combines the two fields in order to improve the urban built environment and reduce the problems associated with the urban transportation sector in Egypt with aid of many of the modern global trends that dealt with this subject and reached many solutions that can be adopted in Egypt. The paper adopted the formulation of a generalized framework that includes the dimension of urban design in the planning and design of urban transport networks and included two pillars. (a) Proposing an ideological framework elaborating the integrated design process, which includes the use of the global modern trends in urban design and urban transportation at the functional urban, social, environmental and economic level; (b) Proposing a theoretical phased design process in line with the local Egyptian reality, which includes different application levels for planning, design, management, development and operation.
Relación entre liderazgo e innovación en las pymes de la comuna once de Medellín
Authors: Beltrán-Ríos Jaime Alberto , López-Giraldo José Antonio , Vélez-Bernal Olga Inés
Published: May 2019

El liderazgo y la innovación son elementos determinantes en el éxito empresarial, ellos hacen parte importante y significativa del proceso administrativo y son condicionantes para llevar a las empresas a la consecución de sus objetivos; éste artículo  busca determinar como el estilo de liderazgo incide  en la adopción de procesos de innovación al interior de las PYMES de la comuna 11 de la ciudad de Medellín, a partir de la identificación de los estilos de liderazgo  y su relación con los proceso de innovación desarrollados al interior de las organizaciones, bajo la aplicación del enfoque cuantitativo y considerando cómo técnicas de recolección de datos la encuesta y la observación directa. Para la instrumentalización de los datos se utilizó una secuencia de análisis deductivo, secuencial, probatorio que analiza la realidad objetiva. Además, la codificación de la información se realizó con base en las categorías predefinidas a partir de la pregunta de investigación. Entre las principales conclusiones se identifica que el estilo participativo es el que potencia el desarrollo de las personas lo que propicia la innovación, la  eficiencia y productividad organizacional.
The deregulation of the salary benefit factors as a competitiveness strategy in Colombia
Authors: Balza-Franco Vladimir
Published: May 2019

En este artículo se comparan los niveles salariales y los factores adicionales al salario que son pagados en algunos países de América Latina y su relación con las políticas de competitividad nacional. A partir de los datos disponibles y el propio juicio del autor, se analizan casos de desarrollo de políticas de desregulación de las leyes laborales vigentes en Colombia, como una estrategia trazada por el gobierno nacional para mejorar la posición competitiva del país. Mediante el contraste de datos de variables como salario mínimo, índice de pobreza multidimensional, índice de desigualdad de Gini e índice de competitividad en países de América latina, con indicadores similares de países avanzados de Europa como Suecia y Alemania, y el análisis de su sistema legal salarial, se llega a la conclusión de que no existe correlación evidente entre la disminución de los salarios de la clase trabajadora y el aumento de la competitividad del país.
Evaluation of the Food and Nutrition Value of Rubus alceifolius Poir. Fruits of Mizoram, India
Authors: Laldinchhana  , Dutta Rajat S. , Thanzami Kawl , Lalhlenmawia Hauzel , Pachuau Lalduhsanga
Published: May 2019

Background:

Lesser known fruits and vegetables could be the source of dietary antioxidants
and nutrition. However, to establish that these fruits and vegetables are important in healthy diet,
it is imperative that thorough scientific investigations are performed. Results and data from such
studies can also help in framing their conservation policy as well as in their promotion.

Objectives:

The present study reports for the first time the physicochemical properties, functional and
antioxidant activities of the wild berry fruit Rubus alceifolius Poir collected from Mizoram, India.

Methods:

The average size, pH, juice content, the fruit acid content and dry matter content were determined.
The antioxidant components of the fruit extract such as anthocyanin, β-carotene, lycopene,
total phenolic and flavonoid contents were also reported.

Results:

The SPF number of the fruit calculated from Mansur’s equation was found to be 1.59 ± 0.03.
HPLC analysis of the fruit extract for phenolic acids showed the presence of ellagic acid and gallic
acid in the acetone-extract.

Conclusion:

Results from studies on various antioxidant activities such as DPPH scavenging, reducing
capability and inhibition of lipid peroxidation indicate that the R. alceifolius fruit possesses
antioxidant activities and its consumption may help in reducing the oxidative stress and preventing
the various degenerative diseases associated with it.
New Insights into the Binding Mechanism of Co-regulator BUD31 to AR AF2 Site: Structural Determination and Analysis of the Mutation Effect
Authors: Song Tianqing , Li Jiazhong
Published: May 2019

Introduction:

Androgen Receptor (AR) plays a pivotal role in the development of male
sex and contributes to prostate cancer growth. Different from other nuclear receptors that bind to
the co-regulator LxxLL motif in coregulator peptide interaction, the AR Ligand Binding Domain
(LBD) prefers to bind to the FxxLF motif. BUD31, a novel co-regulator with FxxLF motif, has
been demonstrated to suppress wild-type and mutated AR-mediated prostate cancer growth.

Methods:

To find out the interaction mechanisms of BUD31 with WT/T877A/W741L AR complex,
molecular dynamics simulations were employed to study the complex BUD31 and
WT/mutant ARs. The molecular mechanics Poisson-Boltzmann surface area (MM-PBSA) results
demonstrated that T877A and W741L point mutations can reduce the binding affinity between
BUD31 and AR. The RMSF and dynamic cross-correlation analysis indicated that amino acid point
mutations can affect the motions of loop residues in the AR structure.

Results:

These results indicated that AR co-regulator binding site AF2 can serve as a target for
drug discovery to solve the resistance problem.
La inmigración haitiana y el componente racista de la cultura dominicana (apuntes para una crítica a 'La isla al revés')
Authors: Dore Cabral Carlos
Published: May 2019

Este texto analiza la inmigración haitiana en la República Dominicana, la cual ha provocado un número importante de fenómenos culturales en el país. Los dominicanos, salvo excepciones, dicen y escriben que en su país no se anida menosprecio alguno por los hombres en razón del color de su piel, sin embargo esos dominicanos, son quienes consideran a los inmigrantes haitianos inferiores en virtud de que la mayoría es negra. Mientras los dominicanos, salvo excepciones, sigan considerando a los haitianos como inferiores por razones intrínsecas, insuperables, como es el color de la piel, cualquier propuesta de esta parte tendrá un sentido no igualitario, al contrario, será de los superiores a los inferiores y esa supuesta diferencia será eterna, pues quienes la plantean consideran que obedece a características adscriptas y no adquiridas. Por tanto el primer paso para un acercamiento franco y duradero entre haitianos y dominicanos, debe ser el abandono de actitudes basas en criterios raciales.
Afectación de la ateroesclerosis en la diabetes
Authors: Estrada Muñoz Mariano , González Pantaleón Adalberto , Carrasco Natali Juan Carlos
Published: May 2019

La ateroesclerosis es un proceso que se inicia tempranamente en la vida del individuo, afectando las arterias de mediano y grueso calibre, y provocando una disminución del flujo sanguíneo tisular. Son muchos los factores relacionados con el desarrollo de la ateroesclerosis. En los diabéticos la afectación ateroesclerosis se presenta en una proporción mucho mayor que en el resto de la población y es responsable de numerosas complicaciones vasculares isquémicas.
Texto e imaginación en las historias, crónicas y relaciones de Indias
Authors: Pérez Odalis C.
Published: May 2019

Las diversas historias y textos constituidos al interior de la cultura colonial invitan a una lectura topológica y lingüístico-textual que puntualiza los acontecimientos históricos y tecnológicos de nuestra formación cultural. El texto histórico de Indias es un texto polifónico, esto es, un texto de múltiples registros y desde el cual se puede leer la cultura de los signos epocales en sus determinaciones formativas. De ahí que texto e imaginación formen una oposición vial propia de las estructuras significativas de la sociedad colonial. Las tecnologías informativas de la sociedad colonial forman parte de un imaginario cultural observable en las cronologías y crono-topías del texto, la crónica y la historia de Indias.
Instituto Tecnológico de Santo Domingo : perspectiva de la gestión rectoral (2002-2005)
Authors: López F. Altagracia
Published: May 2019

Analizar resumen según el género.
Valores generales en una muestra de adolescentes medios de la ciudad de Santo Domingo
Authors: Reynoso Francia
Published: May 2019

La adolescencia es una etapa de la vida que es parte del contínuum, se inicia según la OMS a los 10 años y termina a los 20. Se subclasifica en adolescencia temprana, media y tardía y cada uno de estos apartados tiene sus conductas propias y sus conductas esperadas En el discurrir de la misma se producen cambios en el orden físico, psicológico y social, pero de manera importante se enfatiza la construcción de su identidad y se afianzan, construyen y reformulan sus sistemas axiológicos En esta investigación hemos trabajado con una muestra de 300 adolescentes, de entre 14 y 17 años de edad, de distintos estratos sociales de la ciudad de Santo Domingo, con la intención de conocer sus formas de valorar y el qué valoran Trabajos clásicos como los de Scheler, Hartman, Frondizi nos han servido de marco conceptual para comparar sus postulados con nuestros hallazgos El punto de partida ha sido el de reconocer el valor como lo que vale y no de partir de la predeterminación de los valores como condición para investigar. Lo que ellos y ellas han considerado como válido, como estimable es lo que hemos considerado como valor y no lo que tradicionalmente se ha conocido como tal y que en la mayoría de los casos es referido al valor normal.
Migración transnacional : dominicanos en New York City
Authors: Bissainthe Jean Ghasmann
Published: May 2019

La migración dominicana, como fenómeno social de masa, tiene su origen en la instauración y consolidación de la férrea dictadura (1930-1961) y muerte violenta del dictador Rafael Leonidas Trujillo (30 mayo 1961), la guerra civil e invasión norteamericana de 1965, la apertura de los Estados Unidos a los migrantes no europeos, la llegada y el fortalecimiento en el poder de Joaquín Balaguer (1966-1978), el crecimiento poblacional y la crisis de la industria azucarera en la década de los ochenta El éxodo masivo de los nacionales dominicanos estuvo orientado específicamente hacia Puerto Rico y los Estados Unidos de América, sobre todo hacia la ciudad de New York. Es aquí donde la migración, en cuanto fenómeno dinámico, facilita o hace posible, en un proceso constante de cambios, la transformación del migrante dominicano, quien por encima de la distancia y las fronteras geográficas, logra mantener lazos estrechos con su país de origen, acercándose cada vez más a su tierra natal, raíces, cultura y tradiciones. El Transnacionalismo, pues, lejos de provocar el olvido y el desamor por los suyos y su pequeño terruño, acrecienta, por el contrario, la solidaridad y la dominicanidad.
Perceptions of Educational Leadership Faculty Regarding Open Access Publishing
Authors: Richardson Jayson W. , McLeod Scott , Hurst Todd
Published: May 2019

There is a dearth of research on the perceptions of faculty members in educational leadership regarding open access publications. This reality may exist because of a lack of funding for educational leadership research, financial obstacles, tenure demands, or reputation concerns. It may be that there are simply fewer established open access publishers with reputable impact factors to encourage publication by members in the field. The current study seeks to answer the following question: “What are the perceptions of educational leadership faculty members in UCEA about open access publishing?” The results are based on responses from 180 faculty members in the field of educational leadership.
CARACTERÍSTICAS DO PROCESSO DE COMPRA PELA INTERNET REALIZADA POR ESTUDANTES UNIVERSITÁRIOS
Authors: Pivatto Willian Emilio , Conto Samuel Martim , Braido Gabriel Machado
Published: May 2019

Devido ao desenvolvimento da tecnologia e dos meios de transmissão das informações, o comércio eletrônico ou e-commerce na última década cresceu significativamente. O objetivo deste estudo é caracterizar o comportamento de compra pela internet dos alunos da Universidade do Vale do Taquari - Univates, localizada no município de Lajeado – RS. Para alcançar esse objetivo estabelecido, foi realizada inicialmente a pesquisa qualitativa exploratória, junto a 10 consumidores que habitualmente compram pela internet. Posteriormente, utilizando os resultados dessa etapa, foi aplicado o questionário e respondido por 310 alunos da Instituição. Tratou-se de uma pesquisa quantitativa descritiva, com a finalidade de caracterizar o perfil desses estudantes, a frequência com que realizam compras pela internet, seu valor médio, os principais fatores que influenciam no momento de compra, a categoria mais procurada e também a forma de pagamento utilizada com mais frequência. Após a realização da pesquisa, os dados foram analisados estatisticamente e dentre os principais resultados encontrados, destaca-se o preço dos produtos e serviços oferecidos como fator principal que leva os alunos a comprarem pela internet. Além disso, a maioria dos respondentes realiza pesquisas de preços e produtos nas lojas físicas, antes de efetuar uma aquisição virtual.
When are Firms Sued for Qualitative Disclosures? Implications of the Safe Harbor for Forward-Looking Statements
Authors: Cazier Richard A. , Merkley Kenneth J. , Treu John S.
Published: May 2019

Prior research finds that positive tone in firms' qualitative disclosures increases the risk of shareholder lawsuits. However, federal securities laws provide a safe harbor intended to shield firms' forward-looking statements from legal liability. One implication of this safe harbor is that litigation risk potentially varies between qualitative forward- and non-forward-looking statements. Consistent with this implication, we find that positive tone in forward-looking qualitative statements is significantly less related to the likelihood of subsequent litigation than is positive tone in non-forward-looking qualitative statements. On average, we fail to find a significant association between qualitative forward-looking statements and subsequent litigation. We do find evidence, however, that positive tone in qualitative forward-looking statements relates positively to subsequent litigation in two U.S. circuits in which court rulings reduced safe harbor protections for forward-looking statements. Overall, our results are consistent with the safe harbor effectively shielding firms' qualitative forward-looking statements from litigation risk.
Sell-Side Analysts' Benchmarks
Authors: Kadan Ohad , Madureira Leonardo , Wang Rong , Zach Tzachi
Published: May 2019

Sell-side analysts employ different benchmarks when defining their recommendations. A buy for some brokers means the stock is expected to outperform its industry, while for other brokers, it means the stock is expected to outperform the market or some return threshold. We show that these stated benchmarks have implications for the distribution of recommendations, price reactions to recommendations, and the investment value of recommendations. We conclude that, depending on the question, academics may need to account for the benchmarks when studying analysts' outputs, and investors may find the benchmarks beneficial in interpreting analysts' advice.

JEL Classifications: G10; G24.
LRNA9884, a Novel Smad3-Dependent Long Noncoding RNA, Promotes Diabetic Kidney Injury in db/db Mice via Enhancing MCP-1–Dependent Renal Inflammation
Authors: Zhang Ying-ying , Tang Patrick Ming-Kuen , Tang Philip Chiu-Tsun , Xiao Jun , Huang Xiao-Ru , Yu Chen , Ma Ronald C.W. , Lan Hui-Yao
Published: May 2019

Transforming growth factor-β/Smad3 signaling plays an important role in diabetic nephropathy, but its underlying working mechanism remains largely unexplored. The current study uncovered the pathogenic role and underlying mechanism of a novel Smad3-dependent long noncoding RNA (lncRNA) (LRNA9884) in type 2 diabetic nephropathy (T2DN). We found that LRNA9884 was significantly upregulated in the diabetic kidney of db/db mice at the age of 8 weeks preceding the onset of microalbuminuria and was associated with the progression of diabetic renal injury. LRNA9884 was induced by advanced glycation end products and tightly regulated by Smad3, and its levels were significantly blunted in db/db mice and cells lacking Smad3. More importantly, kidney-specific silencing of LRNA9884 effectively attenuated diabetic kidney injury in db/db mice, as shown by the reduction of histological injury, albuminuria excretion, and serum creatinine. Mechanistically, we identified that LRNA9884 promoted renal inflammation-driven T2DN by triggering MCP-1 production at the transcriptional level, and its direct binding significantly enhanced the promoter activity of MCP-1. Thus, LRNA9884 is a novel Smad3-dependent lncRNA that is highly expressed in db/db mice associated with T2DN development. Targeting of LRNA9884 effectively blocked MCP-1–dependent renal inflammation, therefore suppressing the progressive diabetic renal injury in db/db mice. This study reveals that LRNA9884 may be a novel and precision therapeutic target for T2DN in the future.
Constitutive Activation of β-Catenin in Conventional Dendritic Cells Increases the Insulin Reserve to Ameliorate the Development of Type 2 Diabetes in Mice
Authors: Macdougall Claire E. , Wood Elizabeth G. , Solomou Antonia , Scagliotti Valeria , Taketo Makoto Mark , Gaston-Massuet Carles , Marelli-Berg Federica M. , Charalambous Marika , Longhi M. Paula
Published: May 2019

β-Cell failure is central to the development of type 2 diabetes mellitus (T2DM). Dysregulation of metabolic and inflammatory processes during obesity contributes to the loss of islet function and impaired β-cell insulin secretion. Modulating the immune system, therefore, has the potential to ameliorate diseases. We report that inducing sustained expression of β-catenin in conventional dendritic cells (cDCs) provides a novel mechanism to enhance β-cell insulin secretion. Intriguingly, cDCs with constitutively activated β-catenin induced islet expansion by increasing β-cell proliferation in a model of diet-induced obesity. We further found that inflammation in these islets was reduced. Combined, these effects improved β-cell insulin secretion, suggesting a unique compensatory mechanism driven by cDCs to generate a greater insulin reserve in response to obesity-induced insulin resistance. Our findings highlight the potential of immune modulation to improve β-cell mass and function in T2DM.
FIRST RECORD OF Micrasema cinereum Mosely (TRICHOPTERA, BRACHYCENTRIDAE) IN TURKEY AND A LIST OF THE CADDISFLY FAUNA IN ARAÇ CREEK
Authors: KÜÇÜKBASMACI İbrahim , Fındık Özlem
Published: May 2019

Systematic studies on
Trichoptera larvae in Turkey are very limited. The larval stage of the endemic
species remains especially unknown. This study was carried out in Araç Creek
between April and October 2013 and it is the first study to determine the
caddisfly fauna in Araç Creek. Fourteen caddisflies taxa belonging to nine
genera within eight different families (Brachycentridae, Hydropsychidae,
Hydroptilidae, Lepidostomatidae, Leptoceridae, Limnephilidae, Psychomyiidae and
Rhyacophilidae) were identified. Four of these taxa have previously been recorded
from the creek and the other ten taxa are new records for the study area while Micrasema cinereum Mosely is the first
record for the Trichoptera fauna of Turkey. As a result of the study, the
number of caddisfly taxa in Turkey is now 501, with the addition of M. cinereum.
DETECTING GENDER’S STRATEGIES IN LEARNING SPEAKING
Authors: Anum Adelina , Apriyanto Sigit
Published: May 2019

The researchers intended to know what strategies were used by male and female students in learning speaking, especially at the tenth grade of SMKN Karangpucung and what dominant strategy was used by male and female students in learning speaking. The main question to be answered in this research was concerned with the strategy used by male and female students and what the dominant strategy used by male and female students. The population in this research were 320 students at the tenth grade of SMKN Karangpucung consisting of automotive and accountancy programs, and 32 students were taken as the sample. The instrument used to collect data was a questionnaire consisting of 30 questions to determine the students' strategies used by every male and female student. This research showed that male students tended to use metacognitive strategies and female students tended to use affective strategies. Therefore, the researchers concluded that metacognitive strategies are more likely to be used by male students and affective strategies are more likely to be used by women students. Surprisingly, metacognitive strategies were dominated by male students, while affective strategies were dominated by female students.
¿Es la matemática la nomogonía de la conciencia? Reflexiones acerca del origen de la conciencia y el platonismo matemático de Roger Penrose
Authors: Acosta Miguel
Published: May 2019

Al final de su libro La conciencia inexplicada, Juan Arana señala que la nomología, explicación según las leyes de la naturaleza, requiere de una nomogonía, una consideración del origen de las leyes. Es decir, que el orden que observamos en el mundo natural requiere una instancia previa que ponga ese orden específico. Sabemos que desde la revolución científica la mejor manera de explicar dicha nomología ha sido mediante las matemáticas. Sin embargo, en las últimas décadas se han presentado algunas propuestas basadas en modelos matemáticos que fundamentarían muchos aspectos de la realidad. Dos claros ejemplos provienen de Roger Penrose1 y Max Tegmark2 . Esto lleva a pensar en una posición no solo nomológica sino además nomogónica de la matemática. ¿Puede la Naturaleza estar fundada por las matemáticas como señalan algunos físico-matemáticos? Y en ese caso, ¿sería pertinente buscar una nomo-génesis de esta índole en la constitución de la conciencia?
Mente y cerebro... ¿reduccionismo biológico?
Authors: Jouve de la Barreda Nicolás
Published: May 2019

La neurociencia se ha convertido en un campo de investigación de vanguardia. Se trata de demostrar la existencia de un determinismo biológico de nuestra conciencia y como consecuencia de nuestra conducta… y como consecuencia de nuestra libertad, lo que de llegar a confirmarse conduciría a la negación de la existencia del alma. Este es el argumento central del ensayo sobre los límites de la comprensión naturalista de la mente, con el título “La Conciencia Inexplicada” del Prof. Juan Arana, y la conclusión tras revisar todos los argumentos, hipótesis e intentos que se han hecho hasta ahora para explicar lo inexplicable, es que no hay evidencia empírica ni demostración experimental, sino pura especulación. La conciencia está fuera de los límites de una explicación naturalista. La neurociencia parece discurrir por un derrotero muy parecido al que siguió la genética a principios del siglo XX, cuando la nueva ciencia llevó a una sobreestimación del papel de los genes hasta hacerlos responsables no solo de nuestros rasgos físicos sino también de nuestra conducta. Se trata de corrientes reduccionistas y materialistas. La realidad es que ni los genes lo determinan todo en el ser humano, y menos su comportamiento, ni el sistema nervioso es el único responsable de nuestros actos. Tan solo considerar la mente como una secreción del cerebro es convertir al hombre en pura materia, algo así como una máquina programada. Pensar que eso se puede demostrar experimentalmente es un ejercicio de reduccionismo incompatible con la buena praxis científica.
Naturalismo y hermenéutica de la conciencia. Una discusión con Juan Arana
Authors: Rodríguez Valls Francisco
Published: May 2019

Este ensayo considera las principales tesis del libro La conciencia inexplicada de Juan Arana, en especial la de la inexplicabilidad de la conciencia mediante metodologías naturalistas. Se sostiene la idea de una posible explicación mediante otro tipo de metodología de corte hermenéutico.
Azar físico y libertad. Una epistemología del riesgo
Authors: Soler Gil Francisco José
Published: May 2019

En las páginas siguientes se estudia la ligadura entre libertad e indeterminismo físico asumida en el libro “La conciencia inexplicada” como un caso particular de aplicación de la epistemología del riesgo propuesta por Juan Arana. Se advierte de los riesgos asumidos al ligar libertad con indeterminismo físico, pero se muestra que las alternativas son posiblemente más problemáticas aún.
Idealismo y realismo de la metafísica. En torno a la revitalización del pensamiento aristotélico en Fernando Inciarte
Authors: Carbonell Claudia
Published: May 2019

Este artículo presenta algunos de los hitos de la lectura que hace Fernando Inciarte de Aristóteles. Dicha interpretación supone un cambio de perspectiva respecto a la interpretación convencional de la metafísica aristotélica. Se señalan tres momentos de esa interpretación: el cambio de la clave de lectura metafísica de las Categorías a los libros centrales de la Metafísica; la deducción trascendental de la sustancia y de la esencia; y el redescubrimiento del lugar metafísico de la analogía típicamente aristotélica. El artículo argumenta que la interpretación de Inciarte propone una transformación del aristotelismo del que aún puede sacarse mucho rendimiento. En particular, se presentan algunos de esos rendimientos en el intento por superar el cerco culturalista de la verdad.
Lo angélico y lo posthumano: Encuentro de contrarios en "El ángel caído" de Marina Núñez
Authors: Acedo Nieves
Published: May 2019

El presente texto analiza los múltiples temas que se encuentran en la serie de infografías Ángel Caído que la artista Marina Núñez expuso en la Catedral de Burgos en 2008. En estas obras, cuestiones propias del imaginario de la artista como la ciencia ficción, el feminismo y el transhumanismo se ven afectadas por la fuerza iconográfica y temática de la tradición de la representación angélica. En la primera parte se hace una breve presentación de la obra de la artista para pasar, en la segunda, al estudio de la serie en cuestión como lugar de encuentro entre aspectos propios del humanismo y de la teología judeo-cristiana con preocupaciones propias del cientifismo materialista.
Cristianismo y vida: Ideas en torno a 'Cultura y Verdad' de Fernando Inciarte
Authors: Fernández Gel Enric
Published: May 2019

Presento brevemente dos ideas del libro de Fernando Inciarte con las que trata de resolver la tensión entre cristianismo y mundo/vida: las ideas de una tregua con el mundo y de una continuidad tras el pecado original. Si el cristiano quiere encontrarse con Cristo en el mundo, tiene que pactar una tregua con él. Por otro lado, si bajo la ruptura del pecado original subyace una continuidad, es más difícil ver las tendencias o deseos humanos como productos despreciables del pecado, como se ve en el caso de la sexualidad.
Sensibilidades enfrentadas. Tarkovski o Malick, tiempo o montaje, icono o símbolo
Authors: Alzola Cerero Pablo
Published: May 2019

En presente análisis estudia la posibilidad de vincular el cine de Andréi Tarkovski y Terrence Malick con dos sensibilidades específicas, esto es, con dos modos de concebir el arte en relación con la fe cristiana, siguiendo las reflexiones contenidas en el ensayo “Qué y cómo” de Fernando Inciarte. La hipótesis aquí desarrollada plantea, por un lado, la asociación de la obra de Tarkovski con una sensibilidad icónica y, por otro, la de la obra de Malick con una sensibilidad protestante. Este vínculo no se basa tanto en el contenido (plano conceptual), sino, sobre todo, en la forma artística (plano poético).
The Pedagogical Work of Vieth and GutsMuths
Authors: Virág Irén
Published: May 2019

Introduction:
Philanthropism as it evolved at the end of the 18th century in Germany wanted to break completely with the contemporary methods persisting in education, with the hegemony of classical languages, and with the study of antique authors’ works; instead, it laid emphasis on practical and useful knowledge, on teaching modern languages, on acquiring knowledge based on demonstration, and on an intimate connection to nature. The aim of philanthropist education was to train virtuous citizens who honestly pursue their ordinary profession, in whose training they assigned a central role to physical education.

Purpose:
In our paper, which is a part of our research exploring the appearance of the pedagogical ideas of philanthropism in Hungary, we set out to investigate the question: What was the focus of physical education in the philanthropinums? As a first step in our investigation, we give an overview of the philanthropists’ ideas regarding physical education, then we take a close look at how these ideas were put into practice in two selected institutions, namely among the walls of the philanthropinums in Dessau and Schnepfenthal, by relying on the contemporary works of Gerhard Ulrich Anton Vieth and Johann Christoph Friedrich GutsMuths. Finally, we consider their impact in Hungary.

Methods:
In this study we apply the source analysis as a traditional research method in the history of education.

Conclusions:
The impact of philanthropism on contemporary Hungarian public education, especially in the first half of the 19th century, can be clearly detected, which can be accredited to study trips to Germany and the Hungarian translations of German works. The presence of philanthropism can also be perceived in swimming instruction. Basedow and GutsMuths initiated the instruction of swimming and lifeguarding, and the general institutionalization of swimming instruction. The impact of philanthropists could also be felt in Hungary. Károly (Carl) Csillagh’s textbook on swimming appeared in German in 1841 with the title “Der philantropische Schwimmmeister” (“The Philanthropist Swimming Instructor”). The first book on swimming in Hungarian appeared in 1842.
Desajustamento temporal da escola? Os novos processos de socialização da Geração Z
Authors: De Carvalho Souza Carlos Alexsandro
Published: May 2019

Este trabalho teve o objetivo central de apontar e problematizar, a partir de uma abordagem sociológica, algumas das principais tensões que têm sido representativas das atuais relações entre as instituições escolares e alguns indicadores de mudanças comportamentais de jovens da chamada Geração Z. Procurou-se destacar o descompasso entre a manutenção de alguns discursos tradicionais e o caráter institucional da escola e os variados e inéditos estímulos que passaram a condicionar os comportamentos de uma geração de jovens que impõe às escolas novos desafios em relação à sua função social, suas práticas pedagógicas e, sobremaneira, sua relação com outros espaços de socialização. Este estudo concluiu que, diante disso, existem descompassos entre um recorte geracional, suas expectativas, visões de mundo e demandas, considerando, sobretudo, como a literatura especializada delineia-o e a instituição escolar, que se depara com a necessidade de repensar suas práticas e seu lugar nas sociedades contemporâneas.
The Optimal Control of Two Work-Stealing Deques, Moving One After Another in a Shared Memory
Authors: Barkovsky Eugene Aleksandrovich , Lazutina Anna Aleksandrovna , Sokolov Andrew Vladimirovich
Published: May 2019

In the parallel work-stealing load balancers, each core owns personal buffer of tasks called deque. One end of the deque is used by its owner to add and retrieve tasks, while the second end is used by other cores to steal tasks. In the paper two representation methods of deques are analyzed: partitioned serial cyclic representation of deques (one of the conventional techniques); and the new approach proposed by our team, without partition of shared memory in advance between deques moving one after another in a circle. Previously we analyzed these methods for representing FIFO queues in network applications, where the “One after another” way gave the best result for some values of the system parameters.

Purpose of this research is to construct and analyze models of the process of work with two circular deques located in shared memory, where they movie one after another in a circle. The mathematical model is constructed in the form of a random walk by integer points in the pyramid. The simulation model is constructed using the Monte Carlo method. The used work-stealing strategy is stealing of one element. We propose the mathematical and simulation models of this process and carry out numerical experiments.
Aspectos epidemiológicos das meningites virais no estado do Piauí no período de 2007 a 2017
Authors: Gomes Laércio da Silva , Passos Bruna Victória da Silva , Azevedo Pedro Simão da Silva , Júnior Francisco Tiago dos Santos Silva , Sampaio Leidiana Sousa , Matos Luis Felipe Lima , Nunes Daniel Barbosa , Freitas Joana Elisabeth de Sousa Martins , Moraes Arionildo Batista , Oliveira Lynara Silva , Verde Roseane Mara Cardoso Lima , Oliveira Evaldo Hipólito de
Published: May 2019

Objetivo: Analisar aspectos epidemiológicos das meningites virais no estado do Piauí no período de 2007 a 2017 obtidos no Sistema de Informação de Agravos de Notificação (SINAN). Métodos: Consistiu de um estudo epidemiológico retrospectivo e descritivo de cunho populacional, no qual se empregou dados secundários de casos de portadores de meningites virais ocorridos entre os anos de 2007 a 2017, avaliando aspectos relacionados ao sexo, faixa etária, raça, critérios de confirmação da doença, quantidade de casos nos municípios do estado do Piauí e evolução clínicas da doença. Tabularam-se os dados, utilizando o programa Tabnet, os quais em seguida foram exportados e analisados no programa Microsoft Office Excel 2016. Resultados: Observou-se uma diminuição no número de casos confirmados de meningites virais a partir do ano de 2009. Os indivíduos mais acometidos pela doença são do sexo masculino, com faixa etária entre 05 a 09 anos. A raça predominante é a parda. No que se refere aos munícipios com maior incidência de casos confirmados, Teresina aparece em primeiro lugar. Em relação aos critérios de confirmação, o quimiocitológico foi o mais empregado. Nota-se que a evolução clínica mais recorrente foi à alta hospitalar. Conclusão: Os resultados apontam que está ocorrendo uma redução no número de casos confirmados de meningites virais no estado do Piauí com início no ano de 2009, sendo no município de Teresina o local com mais casos confirmados.
Terra Firma-Forme Dermatosis, Keratotic Form
Authors: Abdalla Jennifer Elise , Cruse Allison , Patel Neelam , Brodell Robert
Published: May 2019

Terra firma-forme dermatosis (TFFD) is a condition that presents as hyperpigmented patches or plaques that have a dirt-like resemblance. A keratotic form of TFFD that has not been previously reported is described in this case. The diagnosis and treatment for this condition, the alcohol swab test, did not lead to resolution of the patch in our patient. The keratotic papules had to be removed by using the edge of a microscope slide. This case report serves to provide awareness of this unique, keratotic variant that cannot be removed by wiping with isopropyl alcohol.
General Framework for Calculating Spin–orbit Couplings Using Spinless One-Particle Density Matrices: Theory and Application to the Equation-of-Motion Coupled-Cluster Wave Functions
Authors: Pokhilko Pavel , Epifanovsky Evgeny , Krylov Anna I.
Published: May 2019

Standard implementations of non-relativistic excited-state calculations compute only one component of spin multiplets (i.e., Ms =0 triplets), however, matrix elements for all components are necessary for calculations of experimentally relevant spin-dependent quantities. To circumvent explicit calculations of all multiplet components, we employ Wigner–Eckart’s theorem. Applied to a reduced one-particle transition density matrix computed for a single multiplet component, Wigner–Eckart’s theorem generates all other spin–orbit matrix elements. In addition to computational efficiency, this approach also resolves the phase issue arising within Born–Oppenheimer’s separation of nuclear and electronic degrees of freedom. A general formalism and its application to the calculations of spin–orbit couplings using equation-of-motion coupled-cluster wave functions is presented. The two-electron contributions are included via the mean-field spin–orbit treatment. Intrinsic issues of constructing spin–orbit mean-field operators for open-shell references are discussed and a resolution is proposed. The method is benchmarked by using several radicals and diradicals. The merits of the approach are illustrated by a calculation of the barrier for spin inversion in a high-spin tris(pyrrolylmethyl)amine Fe(II) complex.
Extreme Scalability of DFT-Based QM/MM MD Simulations Using MiMiC
Authors: Bolnykh Viacheslav , Olsen Jógvan Magnus Haugaard , Meloni Simone , Bircher Martin P. , Ippoliti Emiliano , Carloni Paolo , Rothlisberger Ursula
Published: May 2019

We present a highly scalable DFT-based QM/MM implementation developed within MiMiC, a recently introduced multiscale modeling framework that uses a loose-coupling strategy in conjunction with a multiple-program multiple-data (MPMD) approach. The computation of electrostatic QM/MM interactions is parallelized exploiting both distributed- and shared-memory strategies. Here, we use the efficient CPMD and GROMACS programs as QM and MM engines, respectively. The scalability is demonstrated through large-scale benchmark simulations of realistic biomolecular systems employing GGA and hybrid exchange-correlation functionals. We show that the loose-coupling strategy adopted in MiMiC, with its inherent high flexibility, does not carry any significant computational overhead compared to a tight-coupling scheme. Furthermore, we demonstrate that the adopted parallelization strategy enables scaling of up to 13,000 CPU cores with efficiency above 70%, thus making DFT-based QM/MM MD simulations using hybrid functionals at the nanosecond scale accessible.
Rate Theory for Electrocatalytic Systems: Fixed Potential Formulation for General, Electron Transfer, and Proton-Coupled Electron Transfer Reactions
Authors: Melander Marko
Published: May 2019

Atomistic modeling of electrocatalytic reactions is most naturally conducted within the grand canonical ensemble (GCE) which enables fixed chemical potential calculations. While GCE has been widely adopted for modeling electrochemical and electrocatalytic thermodynamics, the electrochemical reaction rate theory within GCE is lacking. Molecular and condensed phase rate theories are formulated within microcanonical and canonical ensembles, respectively, but electrocatalytic systems described within the GCE require extension of the conventionally used rate theories for computation reaction rates at fixed electrode potentials. In this work, rate theories from (micro) canonical ensemble are generalized to the GCE providing the theoretical basis for the computation reaction rates in electrochemical systems. It is shown that all canonical rate theories can be extended to the GCE. From the generalized grand canonical rate theory developed herein, fixed electrode potential rate equations are derived for i) general reactions within the GCE transition state theory (GCE-TST), ii) adiabatic curve-crossing rate theory within the empirical valence bond theory (GCE-EVB), and iii) (non-) adiabatic electron and proton-coupled electron transfer reactions. The rate expressions can be readily combined with ab initio methods to study reaction kinetics reactions at complex electrochemical interfaces as a function of the electrode potential. The theoretical work herein provides the basis for treating electrochemical kinetics and the inclusion of non-adiabatic and tunneling effects in electrochemical environments widening the scope of reactions amenable to computational studies.
Efektivitas model problem based learning ditinjau dari kemampuan pemecahan masalah matematika
Authors: Jana Padrul , Supiati Endah
Published: May 2019

Penelitian ini bertujuan untuk mengetahui efektivitas model Problem Based Learning dengan pembanding model pembelajaran langsung ditinjau dari kemampuan pemecahan masalah matematika. Penelitian ini dilakukan di SMA Negeri 1 Pajangan dengan mengambil sampel siswa kelas X MIPA 2 sebagai kelas eksperimen dan kelas X MIPA 1 sebagai kelas kontrol. Jenis penelitian ini menggunakan Quasi Eksperiment (eksperimen semu) dengan desain penelitian The Nonequivalent Posttest-Only Control Group Design. Analisis data yang dilakukan yaitu analisis data uji coba soal posttest kemampuan pemecahan masalah matematika, analisis data hasil observasi keterlaksanaan pembelajaran dengan model Problem Based Learning dan model pembelajaran langsung, dan analisis data hasil posttest kemampuan pemecahan masalah matematika yang meliputi uji normalitas dengan menggunakan uji Kolmogorov Smirnov serta uji hipotesis dengan menggunakan uji T dengan taraf signifikansi α = 0,05. Hasil penelitian menunjukkan bahwa kedua kelas dalam keadaan awal yang setimbang. Berdasarkan uji normalitas nilai posttest kemampuan pemecahan masalah matematika pada kelas eksperimen diperoleh nilai sig. 0,057 > α dan pada kelas kontrol diperoleh nilai sig. 0,200 > α, sehingga kedua kelas berdistribusi normal. Berdasarkan uji T nilai posttest kemampuan pemecahan masalah matematika pada kedua kelas diperoleh  > , sehingga dapat disimpulkan bahwa model Problem Based Learning lebih efektiv daripada model pembelajaran langsung ditinjau dari kemampuan pemecahan masalah matematika siswa kelas X MIPA SMA Negeri 1 Pajangan Bantul.
Perancangan Perbaikan Pelayanan Bongkar Muat Dermaga X Dengan Menggunakan Extend Simulasi
Authors: Hartati Misra , Kurniawan Ahmad , Yola Melfa , Siska Merry
Published: May 2019

Large-scale logistics companies deliver products using sea transportation effectively. Company X as one of the pioneer port containers service still has limitations both from minimal stacking capacity and limited equipment, 1 HMC unit and 1 unit reach adapter. The number of containers increases from 2014-2017, but the availability of tools and facilities that needed continue to cause overcapacity problem. This paper aims to determine the yard occupancy ratio (YOR), berth occupancy ratio (BOR) and utility equipment that are in accordance with the standards to prevent overcapacity at port X until 2020. This study uses extend simulation method to make improvements and analysis of conditions that running, the results of the study are recommendations for the addition of 2 units of transport and the addition of reach units of 2 units. For the YOR value, additional capacity from 2,046 TEUs was made to 3,800 TEUs so that the initial maximum YOR was 139.8% to 75.3%, while BOR still in maximum BOR capacity which is 24.0%.Keywords: Container, Discrete Event Simulation, ExtendSim, Port
Notificación de defectos congénitos por brote del virus del Zika en Colombia, 2015-2017
Authors: Mendivelso Duarte Fredy Orlando , Robayo García Adriana , Rodríguez Bedoya Milena , Suárez Rángel Gloria
Published: May 2019

Objetivo. El brote por virus del Zika afectó a varios países tropicales durante 2015 y 2016. Esto obligó a crear estrategias de vigilancia intensificada de microcefalia y otros síndromes neurológicos. Se evaluó el efecto del brote por virus del Zika en la notificación de defectos congénitos en Colombia desde la perspectiva del sistema nacional de vigilancia.

Métodos. Se analizó la notificación nacional de recién nacidos con diferentes defectos congénitos y se determinaron las variaciones en la notificación atribuidas a la epidemia mediante un modelo semiparamétrico denominado “diferencia en diferencias” (DID).

Resultados. Un total de 18 234 casos por defectos congénitos fueron notificados en Colombia durante el período de estudio. La mayoría eran malformaciones congénitas (91,9%). El 82,3% se confirmó por diagnóstico clínico o nexo epidemiológico. En el caso de la microcefalia, se notificaron ocho casos nuevos por semana epidemiológica (coeficiente de notificación de casos [D] = 8,8; P = 0,000) y 32 casos por otras malformaciones congénitas anatómicas (D = 32,0; P = 0,000). El valor absoluto del estimador de diferencia en diferencias atribuido al brote por virus del Zika incrementó la notificación semanal de casos de microcefalia (DID = |-5,0|; P = 0,008) y malformaciones congénitas (DID = |-12,0|; P = 0,111).

Conclusiones. El brote por virus del Zika incrementó la notificación de recién nacidos con microcefalia, pero sin ninguna variación significativa en la notificación de otras malformaciones y defectos congénitos funcionales de origen sensorial o metabólico en el sistema de vigilancia.