bluuebunny/crossref_metadata_2025 huggingface dataset:
Medicines and life (to the 100th anniversary of Professor Irina Vitalievna Zaikonnikova)
Authors: Garaev R S , Ziganshin A U
Published: December 2021

Irina Vitalevna Zaikonnikova is a well-known Soviet pharmacologist, headed the Department of Pharmacology of the Kazan State Medical Institute between 1968 and 1989. The topic of I.V. Zaikonnikovas Ph.D. thesis was The influence of dikain on blood vessels and its relationship with adrenaline. In her dissertation, Irina Vitalievna found that dicaine dilates blood vessels in low concentrations and causes their constriction in high concentrations. The thesis was successfully defended in 1947. In the 50s of the last century in Kazan, for the first time in the Soviet Union, the study of the biological activity of organophosphorus compounds was begun. A large experimental material concerning the correlation between the biological activity and chemical structure of compounds was summarized in his doctoral dissertation Pharmacological characteristics of a number of dialkylphosphinic acid esters, which I.V. Zaikonnikova defended in 1968. At the Department of Pharmacology, which she headed since 1968, a close-knit team was formed, united by a common interest the search and development of new potential drugs. This major work resulted in the creation of cidiphos, glycifon, phosphabenzide, and dimephosphon organophosphorus compounds of a new type, which mechanism of action is not associated with inhibition of the activity of acetylcholinesterase. In addition, drugs that did not belong to organophosphates were created the daytime tranquilizer mebikar, a regeneration stimulator with the immunomodulatory effect of xymedon. At present, the Department of Pharmacology of Kazan State Medical University continues the scientific traditions of our outstanding predecessors.
Kawasaki-multisystem inflammatory syndrome in children in the delayed period of coronavirus infection (covid-19): modern state of the problem and possible new approaches to treatment (plasmapheresis)
Authors: Groznova O. S. , Warriors V. A. , Donich D. , Vetrov V. V. , Ivanov D. O.
Published: December 2021

COVID-19 infection usually occurs in children in a mild form, but some of them in a delayed period (one or several weeks after acute infection with COVID-19) may develop a severe inflammatory disease with clinical manifestations similar to toxic shock syndrome (Kawasaki disease), classified as multisystem inflammatory syndrome in children (MISC). It is possible that the syndrome has only a temporary connection with the COVID-19 infection. In the future, new associations of such clinical manifestations with other infectious (or non-infectious) diseases may appear. But currently, all children in the described cohorts with MISC have an association with COVID-19 infection. It is believed that the syndrome is initiated by an excessive adaptive immune response with the formation of autoantibodies. Treatment is based on anti-inflammatory, including steroid therapy, the possible use of intravenous immunoglobulin, aspirin, interleukin 1 and 6 receptor antagonists. The article analyzes current views on Kawasaki-multisystem inflammatory syndrome in children in the delayed period of COVID-19 coronavirus infection in the aspects of diagnosis, pathogenesis, clinical manifestations (with a discussion of foreign and Russian studies) and approaches to therapy and possible prevention, including the possibility of using plasmapheresis in complex therapy.
Efectos del modelo de financiamiento basado en resultados en República Dominicana sobre los indicadores de salud
Authors: Celhay Pablo , Distrutti Marcela , Martinez Sebastian , Ramírez Indhira , Tapia Kathya
Published: December 2021

Los modelos de financiamiento basado en resultados (FBR) en salud vinculan el financiamiento de los proveedores de servicios a resultados de cobertura y/o calidad en la asistencia sanitaria, con el fin de mejorar la salud de la población. República Dominicana ha implementado un modelo de FBR en la atención primaria desde el año 2010. Este documento presenta la evaluación de la expansión del modelo de FBR en cinco regiones del país entre 2014 y 2018. Métodos: Los coeficientes de cambio en tendencias fueron estimados a través de análisis de series de tiempo interrumpidas y modelos de efectos fijos. El alcance del análisis se limitó a indicadores de vacunación en mujeres embarazadas y niños menores de un año y de insuficiencia respiratoria.
Violencia sexual y basada en género: mapa de ruta para su prevención y atención en América Latina y el Caribe
Authors: Roza Vivian , Martín Carmen
Published: December 2021

La prevalencia de la Violencia Sexual y Basada en Género (VSBG) continúa mostrando cifras muy elevadas en todas las formas en las que ésta se manifiesta y en los lugares donde sucede. Aunque las mujeres y niñas son la mayoría de las víctimas, la VSBG se agrava cuando coincide con más de una dimensión como la raza, etnia, discapacidad, estatus migratorio, orientación sexual, edad, entre otros. Este documento tiene como objetivo generar un mapa de ruta que aporte al diseño, implementación y evaluación de políticas y programas basados en la evidencia disponible para prevenir y atender la VSBG. Así, se encuentra dirigido hacia las personas que diseñan, implementan y evalúan dichas políticas y programas en ALC, pero también para el público general que tenga interés y trabaje en la materia. El mapa está orientado por una teoría de cambio que articula un conjunto de componentes: análisis del problema, las barreras que se enfrentan para prevenir y atender la VSBG y la evidencia disponible sobre intervenciones que se han llevado a cabo y que son producto de evaluaciones experimentales o cuasiexperimentales.
Results of studying the azimuthal anisotropy of the paleozoic basement with vsp technique at the Bystrovka vibroseismic test site
Authors: Gorshkalev S. B. , Karsten V. V. , Dergach P. A.
Published: December 2021

At the Bystrovka vibroseismic test site (Novosibirsk region) 3-component refracted waves profiling was performed at three intersecting lines. Shear waves analysis made possible to detect anisotropy of the Paleozoic basement occurring at depth of about 10 m and to suggest symmetry elements of this medium along with their orientation. Compressional waves data were used to construct depth sections estimating head waves velocities. These velocities demonstrate significant variation in lines of different orientation. The results obtained agree with previously performed VSP.
Velocity models fitting for the seismic events location within the Baikal rift zone
Authors: Belyashov A. V. , Tubanov Ts. A.
Published: December 2021

Whereas the defined velocity model plays a key role in the process of seismic events localization, so selection of the model as much as possible corresponding to the real velocity conditions of the investigated area becomes a crucial task. Basing on the analyses of published results of the Lake Baikal area seismic study a layered P-waves models for two situations defined: For the high velocity consolidated rock on the lake banks and low velocity sediments up to 10 km thick under the lake bottom.
Structural description and tectonic development history of the mesozoic deposits in the Vilyui hemisyneclise
Authors: Kosmacheva A. Yu. , Fedorovich M. O.
Published: December 2021

We present the interpretation of 2D seismic data in the Vilyui hemisyneclise located in the Republic of Sakha (Yakutia). The model identifies structural and tectonic features and tectonic development history of the Mesozoic deposits in the Vilyui hemisyneclise. Structure contour maps for the reflecting horizons of the Mesozoic are qualitatively the same. Traced faults attenuate at various stratigraphic levels. The structures of the hemisyneclise are known to be formed during the Cretaceous stage of development.
Baim Boltin as a participant in the conclusion of the Polyanovsk peace treaty and demarcation of borders
Authors:   Saratov State University, Vtyurin Andrey S.
Published: December 2021

This article is devoted to the role of the little-known nobleman Baim Fedorovich Boltin in the peace negotiations between Russia and the Polish-Lithuanian Commonwealth after the end of the Smolensk War of 1632-1634 and in the delimitation of disputed territories. The work considers: the processes of organizing embassies, the work of demarcation commissions, parochial disputes between the participants in these events.
Historical assessments in Estonian society: The identity of Estonians and Russian speakers in the context of local memory politics
Authors:   Department of History of Kostroma State University, Zverev Kirill A.
Published: December 2021

The article examines the foundations of the historical paradigm of the modern Republic of Estonia and the degree of its perception by the local population. With the proclamation of independence, the local establishment decided to completely break with the Soviet past and had to construct not only its own political mechanism, the vertical of power, but also a new historical paradigm that could become a fastening link of the emerging statehood, as well as the Estonian society itself (its Estonian-speaking and Russian-speaking parts). The Estonian memory policy directly influenced the shaping of the collective identity of the local population – to a greater extent Estonians than Russian speakers. The state historical policy failed to become a fastening link for the multinational Republic and predictably defends (and even implants) the historical views of the titular population, without considering other points of view.
EXERCISING OF JUDICIAL CONTROL OVER NOTARIAL ACTIVITIES: SOME CHALLENGING ISSUES
Authors:   Associate Professor of the Department of Civil Law and Procedure of the Immanuel Kant Baltic Federal University PhD (Law), Yaroshenko Tatyana V.
Published: December 2021

The article reveals the procedure for exercising judicial control over notarial activities, analyzes the main types of control, identifies some problematic issues of proposals for improving legislation.
THE SOCIAL EFFECT OF THE FREEDOM OF WILLS AS REFLECTED BY THE JUDICIAL PRACTICE
Authors:   Head of the Department of Civil Law of the Kuban State University, LL.D., Professor, Schennikova Larisa V.
Published: December 2021

The author proves the idea of sanctity of the testator’s will and the development of opportunities for its most complete implementation in the laws as well as in the modern notarial practice. Judicial practice in cases on acknowledgment of a will invalid is in the center of the author’s attention. Its analysis has allowed to identify the tendency of acknowledgment of wills made in favor of persons taking care of the elderly over the last years of their lives invalid based on claims of relatives showing no concern and paying no attention to the elderly during their lifetime. In the meantime, wrongful acts of notaries expressed in violation of the procedure and the rules for performance of notarial actions have served as the grounds for acknowledgment of wills invalid. The author encourages notaries and judges to pay more attention to the testator’s will (intentions) and create all conditions to implement such will after the testator’s death as adequately as possible.
Presiding Judge and Court Administrator in the Conditions of Legal Reality
Authors:   Postgraduate Student of the Institute of Legislation and Comparative Law under the Government of the Russian Federation, Koroleva Elena V.
Published: December 2021

In the theory of law, the main prerequisite for the introduction of the institution of the court administrator was the so-called unloading of the Chairman from part of the organizational and administrative functions. In this article, the author reveals the conflict between the understanding of the status of the Chairman and administrator of the court with the legal reality, the stages of formation and correction of the institution under study. Despite the fact that the doctrine has long discussed the need for such a specialist as a court administrator, his position in the judicial system, the limits of competence are significantly limited and do not allow achieving the goals set by the legislator. In the article, the author tries to reveal the reasons for this discrepancy, problems of interaction, double subordination and subordination of the Chairman and administrator of the court, guided by regulations, expert assessments, comments of representatives of the judicial community.
The Use of Modern Information Technology in Judicial Review of Complaints in Pre-Trial Proceedings
Authors:   1st Year Intramural Junior Scientific Assistant of the Department of Criminal Procedure of the Saint-Petersburg University of the Ministry of the Interior of the Russian Federation, Mirgorodskaya Elvira R.
Published: December 2021

This article is devoted to the topical issue of the institution of judicial control — ensuring the right to access to justice in the context of digitalization of public relations. According to the analysis of the statistical data of the Judicial Department of the Russian Federation, on the lion’s share of complaints (about 70%) accepted for proceedings, decisions are made to terminate proceedings on various grounds, and only a third of the complaints are decided to satisfy or refuse to satisfy the complaint. The author has analyzed the main reasons for the termination of the proceedings on the complaint, taking into account the existing current judicial practice. The practical significance of the work lies in the availability of proposals for resolving existing problems that are practically oriented towards the judicial system, taking into account the use of modern information technology of the state automated system «Justice» and video conferencing systems. In order to improve judicial control in pre-trial proceedings, the author’s vision of making changes at the legislative level was formulated by amending Part 2 of Art. 125 of the Criminal Procedure Code of the Russian Federation.
Conspiracy theories and pandemic management in Africa: critical reflections on contexts, contradictions and challenges
Authors: Oyekan Adeolu Oluwaseyi
Published: December 2021

The coronavirus pandemic, though primarily a health issue, has had significant social, economic and political implications across the world. There are reasons to believe that some of the changes occurring are likely to be permanent even in a post-pandemic world, and there are even suggestions that the world may be entering a phase in which pandemics become recurrent. Making sense of all that the pandemic has brought has by no means been easy, even for scientists who have had to review and revise their claims as new discoveries about the virus are made. One of the fallouts of the pandemic has been a proliferation of conspiracy theories about the origin of the virus, as well as efforts to contain it. Summed up, these theories of various shades allege that certain powerful forces are behind the pandemic, in pursuit of some narrow ends that range from the political to the religious. In this paper, I analyse conspiracy theories and the motivations behind them. Situating conspiracy theories within the pandemic, I argue that they are best understood not within the framework of a single theory but by an understanding of how diverse motivations generate different, even contradictory conspiratorial accounts. I argue that whereas conspiracy theories have become a feature of modern society, and have been amplified in the age of technology, they have low credibility value in explaining the pandemic, while having significant implications. I also argue that if left unchecked, conspiracy theories have the capacity to further undermine governments’ capacity to respond to big crises in Africa in the future. I conclude that conspiracy theories are best managed in a pandemic through consistent, transparent engagement rooted in trust-building between the people and governments, especially in Africa.
Politicising ‘Covid-19’: an analysis of selected ZANU-PF officials’ 2020-2021 media statements on the pandemic in Zimbabwe
Authors: Mutekwe Paddington , Vanyoro Kudzaiishe  Peter
Published: December 2021

This paper examines the politicisation of Covid-19 in Zimbabwe through discourse analysis of selected media statements released by Zimbabwe African National Union-Patriotic Front (ZANU-PF) officials on the Covid-19 pandemic between March 2020 and February 2021. Theoretically, the paper employs Foucault’s theory of biopower to interpret the state- citizen power relations that surfaced in the Zimbabwean government’s response to the Covid-19 pandemic. It argues that the ZANU-PF-led government used Covid-19 as an excuse to pursue its political interests. This is politics that protected ZANU-PF’s social, political and economic interests by using Covid-19 as an excuse to pulverise various forms of opposition. The argument advanced herein is that while the implementation of the lockdown in Zimbabwe was necessary to save lives, one of its consequences was the protection of self-interests through selective application of lockdown regulations and the passing of laws to silence critics. This resulted in the prohibition of political gatherings, arbitrary arrests, labelling and name-calling of the opposition and the West by ZANU-PF officials who were safeguarding their party’s waning support resulting from their mismanagement of the pandemic.
Shame, subjectivity, and pandemic productivity
Authors: Easterbrook-Smith Gwyn
Published: December 2021

As the COVID-19 pandemic spread across the globe, the lockdown, isolation, and quarantine restrictions which were put in place in many countries obliged many people to begin working from home. Concurrently, advice in the form of articles and social media posts emerged, urging people to use the ‘opportunity’ of isolation during the pandemic to engage in self-improvement activities or launch a business. In this paper, I consider the ways that the temporal collapse between private and work life can be seen to exacerbate the degree to which these productivity discourses played upon neoliberal conceptions of identity formation through self-commodification and optimisation. The discourses frequently used a combination of shame and the suggestion that productivity was an obligation to the community, as well as to the self, to justify themselves and make finding purchase to engage in a critique of the broader structural issues at play more rhetorically difficult.
Procedimiento para caracterizar analizadores de descargas parciales de HF, VHF y UHF utilizados para el diagóstico de las redes e instalaciones de alta tensión
Authors: Garnacho Fernando , Khamlichi Abderrahim , Rivera Jorge , Simón Pascual , Ramírez Ángel , Álvarez Fernando
Published: December 2021

La monitorización y medida de las descargas parciales en las redes eléctricas e instalaciones de alta tensión para evaluar el estado del aislamiento de los activos es un tema de gran actualidad, sin embargo, no existen criterios ni procedimientos para evaluar las características técnicas de estos sistemas de medida y diagnóstico. Los sistemas de cable se monitorizan con sensores de tipo HFCT por tener alcances de medida de varios kilómetros cada sensor. En las instalaciones GIS, los sensores invasivos de tipo UHF son ampliamente utilizados, al presentar alta sensibilidad para detectar pequeñas DP pese a su corto su alcance de pocos metros y para los transformadores de potencia se utilizan las capacidades de las bornas capacitivas, como condensador de acoplamiento acoplado a una impedancia de medida. Aunque aparentemente no existe una solución universal para resolver el mismo problema “detección del defecto del aislamiento eléctrico”, en realidad no son bien conocidas las capacidades que tienen las diferentes técnicas de medida convencionales, en HF, VHF y las de UHF.

En este artículo se presenta un procedimiento de ensayo desarrollado con motivo del proyecto europeo “FuturEnergy” dentro del programa EURAMET que utiliza un banco de ensayo monofásico de alta tensión (20 kV) compuesto por una GIS y un sistema de cable que permite realizar pruebas de caracterización de sistemas de medida que utilicen sensores de tipo convencional, HFCT, VHF y de UHF. Las descargas parciales son generadas por un conjunto de probetas de referencia diseñadas al efecto o por un generador de trenes de pulsos de DP de referencia utilizado como calibrador.
Simulación de redes eléctricas con procesamiento paralelo mediante Matlab
Authors: López-Coronado Dante , Ceja-Cerrato Iván , Galván-Sánchez Verónica A. , Gutiérrez-Robles José A. , López-de-Alba Carlos A. , Bañuelos-Cabral Eduardo S. , García-Sánchez Jorge L. , Sotelo-Castañón Julián , Nuño-Ayón José de Jesús
Published: December 2021

En este artículo se describe el desarrollo de una metodología para simular la dinámica de una red de energía eléctrica a través del procesamiento paralelo. Los sistemas eléctricos se modelan mediante ecuaciones diferenciales, por lo que es necesaria la implementación de métodos numéricos para encontrar la solución de dichas ecuaciones. La metodología consiste en la división de una red eléctrica en subredes que están desacopladas en tiempo entre sí, es decir, las subredes resultantes se encuentran conectadas entre sí mediante líneas de transmisión. El tiempo de viaje a través de las líneas produce el desacoplamiento en tiempo necesario para que la solución de las ecuaciones diferenciales pertenecientes a cada una de las subredes se pueda obtener en paralelo. El caso de estudio principal es una red eléctrica sencilla y para su simulación con Matlab se utiliza de la librería de procesamiento paralelo. Los resultados obtenidos con la técnica de procesamiento paralelo se comparan con la simulación secuencial también implementada en Matlab y con el ATP (del inglés Alternative Transient Program) para validar los resultados obtenidos.
Redes neuronales artificiales para la predicción de flujos de carga aplicadas al sistema de trasmisión de Uruguay
Authors: Garabedian Santiago , Porteiro Rodrigo , Pena Pablo
Published: December 2021

En el presente trabajo se propone el uso de redes neuronales artificiales para la resolución del problema de flujos de carga. El estudio del flujo de carga de la red eléctrica constituye una herramienta fundamental para la operación y la planificación de un sistema eléctrico. En términos matemáticos el problema de flujos de carga se resuelve a través de un sistema de ecuaciones no lineales. Para dicha resolución tradicionalmente se han utilizado diversos métodos numéricos, principalmente el método de Newton-Raphson y sus variantes. Estos métodos numéricos aplicados a sistemas eléctricos de gran tamaño tienen un alto costo computacional asociado. Resolver una cantidad considerable de flujos de carga utilizando estos métodos implica incurrir en tiempos de ejecución que resultan prohibitivos en estudios sobre la red eléctrica. Este problema se vuelve crítico en estudios de casos de contingencia, incluso utilizando el criterio simple de contingencia N-1. La construcción de redes neuronales que aproximen la resolución de flujos de carga permite reducir significativamente los tiempos de ejecución de los estudios anteriormente mencionados. En este trabajo se propone el diseño de una arquitectura de red neuronal para la aproximación de flujos de carga. Utilizando la arquitectura diseñada se implementa un modelo de aproximación de flujos de carga. La validación de la herramienta se realiza utilizando la red de trasmisión de Uruguay. La aproximación obtenida para este caso de estudio es evaluada aplicando la métrica MAPE y se obtiene un valor de 2.6%, lo que constituye un resultado muy prometedor.
Metodologia para geração de sinais de arco elétrico para otimização de cenários de medições
Authors: De Lyra Ramos Nieremberg J. P. , Rene Serres Alexandre Jean , Guedes da Costa Edson , Gomes Neto Alfredo
Published: December 2021

As subestações concentram equipamentos essenciais para o funcionamento das redes de distribuição de energia elétrica. O diagnóstico do estado de degradação dos equipamentos é muito importante, em especial dos disjuntores que são os responsáveis por seccionar a rede. Uma técnica que tem se destacado é o diagnóstico de disjuntores a partir da análise do sinal irradiado pelo arco elétrico, que ocorre na comutação de estados nos disjuntores. Essa técnica compreende a captação do sinal irradiado, seu armazenamento em formato digital, e análise a partir de informações obtidas. Um problema que essa técnica enfrenta é a otimização dos cenários de medições, pois para isso é necessário estar em uma subestação, onde as comutações são realizadas sem controle dos pesquisadores, ou possuir disjuntores em laboratório. Porém, em laboratório existem limitações quanto aos tipos de disjuntores pela impossibilidade de ter vários disjuntores em laboratório. A metodologia de otimização proposta neste artigo visa a reprodução de sinais radiométricos de arcos elétricos, previamente adquiridos, em subestações ou em laboratório, tornando possível simular em ambiente experimental disjuntores diversos, em diferentes estágios de degradação. Dessa forma, é possível otimizar os cenários de medições, variando distâncias e posicionamentos das antenas e de outros elementos, realizando medições sucessivas para obter a melhor configuração de medição.
„Šta izaziva osnovne emocije?“ – učestalost simboličkih pobuđivača u odgovorima ispitanika različitog uzrasta
Authors: Simunović Vojin M.
Published: December 2021

Iako je odavno poznato da simbolički stimulusi mogu da budu pobuđivači emocija, dosadašnja istraživanja u oblasti socijalne kognicije (tj. teorije uma) bila su usmerena gotovo isključivo na prirodne pobuđivače. Zato smo ispitanicima različite starosti, koristeći metodu strukturisanog intervjua, postavljali pitanja o tome šta izaziva 4 osnovne (radost, strah, tuga, bes) emocije, kako bismo utvrdili kolika će biti relativna učestalost simboličkih pobuđivača u njihovim spontanim odgovorima. Relativna učestalost takvih pobuđivača uzeta je kao indikator za njihov značaj za razumevanje kauzacije emocija. Učestvovalo je ukupno 120 ispitanika, po 20 na različitim uzrastima od predškolskog do studentskog. Dobijene odgovore kategorisala su dva nezavisna procenjivača; ukupno slaganje među njima bilo je 96%. Rezultati su pokazali da su simboličke pobuđivače u visokom procentu navodili ispitanici na svim ispitivanim uzrastima. Ovaj nalaz smo protumačili kao pokazatelj toga da su takvi pobuđivači od najranijih uzrasta deo implicitne teorije o kauzaciji emocija i da je u dosadašnjim istraživanjima napravljen „propust“ time što oni nisu u većoj meri uzeti u obzir. Jedina značajna uzrasna razlika u učestalosti simboličkih pobuđivača dobijena je između dece od 5 godina (46.4%) i starijih ispitanika (65.9% u proseku), što se poklapa sa prelaskom sa predškolskog na školski uzrast. Relativna učestalost takvih pobuđivača ostaje približno ista na starijim uzrastima. Analize uzrasnih razlika u učestalosti simboličkih pobuđivača iz različitih potkategorija pokazale su da je na uzrastu od 5 godina veća učestalost ikoničkih pobuđivača nego na starijim uzrastima, dok je obrnut slučaj sa društveno-normativnim pobuđivačima; u oba slučaja, kasnije uzrasne razlike nisu statistički značajne.
Relacije Mračne tetrade, aleksitimije i distresa: analiza na nivou faceta, antagonističkog i agensnog faktora mračnih crta
Authors: Dinić Bojana M. , Cmiljanić Anđela , Rokvić Nikola
Published: December 2021

Osnovni cilj ovog istraživanja je utvrđivanje relacija između crta Mračne tetrade i faktora aleksitimije, uzimajući u obzir multidimenzionalnu prirodu mračnih crta, kao i njihove antagonističke (maladaptivne) aspekte i aspekte delotvornosti ili agensne aspekte (adaptivnije aspekte). Dodatno, ispitana je medijatorska uloga faktora aleksitimije u odnosu između mračnih crta i distresa. Na uzorku od 355 ispitanika (71.3% ženskog pola) iz opšte populacije, primenjeni su sledeći instrumenti: Toronto skala aleksitimije, Skala depresije, anksioznosti i stresa, Levensonova skala psihopatije, Petofaktorski inventar makijavelizma, Kratka verzija Petofaktorskog inventara narcizma, Procena sadističke ličnosti. Rezultati pokazuju da mračne crte i faktori aleksitimije dele 56% zajedničke varijanse, te da su dominantni prediktori aleksitimije sekundarna psihopatija u pozitivnom smeru i makijavelistička delotvornost u negativnom smeru, a potom i narcistički antagonizam i primarna psihopatija, oba u pozitivnom smeru. Rezultati pokazuju da faktor mračnih crta koji okuplja agensne karakteristike na pozitivnom polu ostvaruje veći i negativni doprinos u objašnjenju aleksitimije i distresa, u odnosu na faktor koji okuplja primarno antagonističke karakteristike. Mračnim crtama je najviše objašnjen faktor aleksitimije koji se odnosi na probleme u identifikaciji emocija, i ujedno je ovaj faktor značajan medijator u predikciji distresa na osnovu  sekundarne psihopatije, makijavelističke delotvornosti ili oba faktora mračnih crta. Naime, ovaj kognitivni deficit u razumevanju emocija doprinosi povećanju distresa u slučaju primarno antagonističkih mračnih crta, dok faktor delotvornosti preko manjih problema u identifikaciji emocija doprinosi redukciji distresa.
Mirtazapine Induced Akathisia:A Case Report
Authors: DENİZ ÖZTURAN Deniz , ÜNAL DEMİR Figen
Published: December 2021

Akathisia is a movement disorder characterized by an inner sense of restlessness and it needs attention because of the increased risk of suicidal behavior. Although akathisia may affect the trunk and arms, it predominantly affects the legs. Akathisia may occur exposure to antipsychotics and antidepressants. Mirtazapine is an antidepressant blocking presynapticα-2adrenergic receptors and 5-hydroxytryptamine (5-HT) 2A/2C, 5 HT 3 and histaminergic postsynaptic receptor. In this single case study, we aimed to present a case of akathisia which occurred after mirtazapine treatment.Case presentation: A fifty -two-years-old woman presented with a-one-month history of decreased sleep and appetite. She had been using antidepressant medication (Fluoxetine 40 mg / day) for five months due to depressive disorder. Mirtazapine 15 mg/day was added to the patient's treatment. Three hours after the first dosage she could not sit even for few minutes and complained of inner restlessness. She reported feeling anxious. Biochemical tests for metabolic/electrolyte parameters were within reference ranges. She had no neurological disease. Mirtazapine was removed and her symptoms resolved in one day.She consulted the department of internal medicine. Her physical examination was normal. Biochemical tests for metabolic/electrolyte parameters were within reference ranges. She had no neurological disease. Mirtazapine was removed and her symptoms resolved in one day.Akathisia is an important side effect because of related to a subjective experience of discomfort that can lead to suicidal behavior. This case illustrates the significant of being alert to any movement disorders in patients treated with mirtazapine.
The Effects of Variable Selection and Dimension Reduction Methods on the Classification Model in the Small Round Blue Cell Tumor Dataset
Authors: YAĞIN Fatma Hilal , KÜÇÜKAKÇALI Zeynep , BALIKÇI ÇİÇEK İpek , GÖZÜKARA BAĞ Harika
Published: December 2021

Objective: The purpose of this study is to investigate and compare the effects of different dimension reduction methods (PCA, ICA, PCA + Forward Selection, ICA + Forward Selection) on the K-NN classifier using open access gene expression data of small round blue cell tumor types.Methods: In this study, open access gene expression data of small round blue cell tumor types was used for investigate and compare the effects of different dimension reduction methods. In the study, PCA, ICA, PCA + Forward Selection, ICA + Forward Selection were used as different dimension reduction methods together with K-NN classification method.Results: Accuracy values obtained from the dimension reduction model made with PCA on K-NN model; for EWS, BL, NB, and RMS type tumors with 93.51%, 91.14%, 92.31%, and 94.74% respectively. Accuracy values obtained from the dimension reduction model made with PCA + Forward Selection on K-NN model; for EWS, BL, NB, and RMS type tumors with 96.25%, 96.25%, 95.06% and 95.47%, respectively. Accuracy values obtained from the dimension reduction model made with ICA on K-NN model; for EWS, BL, NB, and RMS type tumors with 91.89%, 90.67%, 88.31% and 89.47% respectively. Accuracy values obtained from the dimension reduction model made with ICA+ Forward Selection on K-NN model; for EWS, BL, NB, and RMS type tumors with 93.51%, 91.14%, 92.31% and 94.74% respectively.Conclusion: In this study, the model created with PCA gives higher results than the model created with ICA. In addition, according to the results of the models obtained by applying the Forward selection method on these 2 models, the forward selection method has increased the classification performance.
Clasificación del paisaje y referencia espacial en cmiique iitom (seri)
Authors:   Universidad Nacional Autónoma de México, Instituto de Investigaciones Filológicas, O'Meara Carolyn Kristen
Published: December 2021

El dominio del paisaje es un área de mucho interés en la investigación de la categorización lingüística pero, al mismo tiempo, presenta algunas posibles dificultades. Por ejemplo, ¿qué significa el término español "montaña" para los hablantes de determinada lengua? ¿Es un accidente geográfico convexo necesariamente más alto que el accidente geográfico llamado "cerro"? ¿Una montaña tiene que tener una cima puntiaguda o cresta, o puede tener una cima redondeada? ¿Dónde están los límites de una montaña, dónde empieza y dónde termina? Las respuestas definitivas a estas preguntas no son fáciles de encontrar. En este estudio se describe la gramática de referencia espacial en seri, mediante la ocurrencia de términos del paisaje como elementos nominales que denotan fondos en descripciones locativas o en descripciones de eventos en movimiento, así como en anclas en algunos marcos de referencia.
PERINE OSTOMY IN SURGICAL CORRECTION UPON EXTENDED AND RECURRENT STRICTURES OF THE ANTERIOR URETHRA
Authors: Morozov E. A , Panin S. I , Kushniruk N. E , Kuznetsov A. A , Goncharov N. A , Doronin A. B , Linchenko D. V
Published: December 2021

The aim of the research is to evaluate the results of trapezoidal perineostomy in the treatment of patients with extended and recurrent strictures of the anterior urethra. The study included 5 males with an average age of 62 years. Among the etiological factors: urethrectomy and penectomy (n = 3), inflammatory diseases of the urethra (n = 1), iatrogenic damage to the urethra (n = 1). The duration of the operation is 60 minutes. No complications were observed in the immediate postoperative period. The average bed-day in the hospital was 4, postoperative - 3 days. When assessing long-term results and quality of life using questionnaire scales, the following results were obtained: IPSS - 5 (3-7) points and QoL - 1 (1-2) points. Thus, perineal urethrostomy requires more extensive and detailed analysis in studies with high statistical power.
DIAGNOSIS OF OSSIFICATION USING COMPUTED TOMOGRAPHY METHODS IN PATIENTS DIAGNOSED WITH FIBRODYSPLASIA OSSIFYING PROGRESSIVE
Authors: Sevbitov A. V , Danshina S. D , Borisov V. V , Platonova V. V , Kuznetsov I. I
Published: December 2021

Methods of bone density are described. A variety of computer programs are used to decrypt computed tomography. In our study, we compared the Blue Sky Plan programs from BlueSkyBio and Ez3D2009 from Vatech. Assessment of bone tissue density allows obtaining data for diagnosis and predicting the consequences of planned invasive treatment.
COLORIMETRIC ANALYSIS IN ESTIMATING THE EFFICIENCY OF TRABECULOCLINIG
Authors: Dzhashi B. G , Balalin S. V
Published: December 2021

Trabeculoclining is usually called the aspiration of debris during phacosurgery, which is of fundamental importance in cataracts associated with open-angle glaucoma and pseudoexfoliative syndrome. One of the methods for objectively assessing the results of this surgical manipulation is the colorimetric analysis of the structures of the anterior chamber angle. We examined 110 patients with the initial stage of primary open-angle glaucoma (110 eyes). The aim of this study was to assess the state of the anterior chamber angle after trabeculoclining based on the colorimetric analysis. The change in the color state of the structures of the anterior chamber angle after trabeculoclining was investigated. Photo registration of zones was carried out with subsequent colorimetric analysis. The change in the average color of the Schlemm canal is clearly shown. The method confirmed the effectiveness of trabeculoclining in terms of trabecular debris aspiration and showed a reliable clarification of the photorecorded structures.
ASSESSMENT OF THE PHYSICAL DEVELOPMENT OF SCHOOLCHILDREN AGED 9-10 YEAR-OLD LIVING IN THE ALTAI REPUBLIC
Authors: Bauer P. S , Borodina G. N , Trebushinina T. G , Fedina I. Yu.
Published: December 2021

The article presents the results of the medical examination of schoolchildren aged 9-10 years living in the Altai Republic. Anthropometric measurements assessing the level of schoolchildren physical development were carried out. The study revealed a low level of schoolchildren physical development in the presented age group, underweight in children of both sexes being more prominent in females. At the beginning of the academic year, children were characterized by an asthenic body type. At the end of the year, the parameters characterizing the body type were within the recommended values. The causes of the low level of physical development may be the special characteristics of the climate and geographical zone where the studied children live, the diet and the lack of physical activity which is necessary for the normal body development.
ETHICAL EXAMINATION OF SCIENTIFIC PUBLICATIONS IN MEDICINE: FOREIGN EXPERIENCE AND RUSSIAN PRACTICE
Authors: Alshuk Natalia A. , Kostenko Svetlana A. , Golitsyna Olga Yu.
Published: December 2021

Abstract. Currently, much attention is paid to the correct presentation of the results of. This is not surprising, since international standards used for assessing the effectiveness of scientific clinical and pre-clinical studies in scientific publications activities are based on citation rates and the number of publications in peer-reviewed journals. This tradition originated in the UK and is the result of a struggle for grants in the scientific community. The Hirsch index (individual authors) type of assessment and the impact factor (journals) made it possible to quantitatively compare papers without referring to their content. The assessment of the latter was accomplished by editors of the journals, and it was assumed that it was objective. This method was consistent with the digitalization process, but it has not yet received an ethical assessment. This is happening not only because there is a fairly wide range of opinions on this issue in the scientific community [1], but also because moral plots are generally not referred to digital processes.
CYNICISM AS A MANIFESTATION OF PROFESSIONAL DEFORMATION OF THE DOCTOR'S PERSONALITY
Authors: Svetlichnaya Tatiana G. , Dernova Alyona S. , Kosolapova Marina A.
Published: December 2021

Abstract. The article is devoted to the actual problem of the professional deformation of the doctor's personality. In the aggregate of the negative characteristics of the emotional burnout of doctors, one of the most destructive is cynicism, manifested in a disdain for cultural values and generally accepted norms of morality and ethics. The aim of the work was to comprehend the nature of the socio-psychological phenomenon "cynicism", to establish the factors that contribute to its occurrence and overcoming. The materials that have been used for research were the scientific articles for 20032021 published in scientific databases such as eLIBRARY.RU. and cyberleninka.ru, and the scientific works of the Russian writer and doctor V.V. Veresaev (18671945) and the Russian surgeon N.I. Pirogov (18101881). The study found that cynicism, which is a leading and socially significant problem of a doctor's professional activity, is an acquired undesirable personality characteristic. The authors systematized the factors influencing the development of cynicism, considered effective ways of its prevention and correction.
ETHICAL AND SOCIOLOGICAL ASSESSMENT OF ATTITUDES TO VACCINATION IN THE YOUTH ENVIRONMENT OF RUSSIA
Authors: Donika Alena D. , Yagupov Pavel R. , Klimke Ansgar , Yagupov Robert P.
Published: December 2021

Abstract. The prolonged COVID-19 pandemic on the background of a shortage of state resources in the healthcare sphere, caused a wave of pseudoscientific information in the Internet. The youth environment is particularly susceptible to such influence, communication in which has the character of information chaos. To assess the attitude to vaccination in the youth environment of Russia, a sociological study was conducted, N = 480, average age (20.8 1.41). According to the data obtained, 36.71 % of respondents are categorically against personal vaccination. At the same time, only 65.71 % of students who gave a negative answer were able to explain their position. The obtained results demonstrate a tendency to the formation of a socially negative "fashion" among young people "dissident-vaccines". It is shown that the fundamental difference is that the stigmatization of those who are
not vaccinated abroad can be provoked by inequality in access to vaccines, and not a protest manifestation of infodemia, as among young people of Russia. Because of this, the demand for socio-psychological support of vocational education is increasing, where in the conditions of the educational environment, sociological monitoring, moral and psychological correction seems to be the most realistic. In such conditions, the demand for humanitarian education in medical universities is increasing, which allow to focus on ethical norms and moral values of the profession within the educational process.
Le Laboratoire de Farcha et les programmes d’éradication de la peste bovine au Tchad de 1949 à 2007 : une synthèse
Authors: Deye Adam Hassane , Duteurtre Guillaume , Ouagal Mahamat
Published: December 2021

Ce travail de synthèse présente le rôle de l’Institut de recherche en élevage pour le développement (IRED), anciennement Laboratoire de Farcha, dans la lutte contre la peste bovine au Tchad. Créé en 1949 par les autorités coloniales, ce laboratoire implanté à N’Djamena joue dès sa création un rôle déterminant dans les recherches sur la peste bovine en Afrique centrale. Dans la première période, ou « temps des vaccins » (1953–1961), les travaux du laboratoire conduisent notamment à la fabrication de plusieurs générations de vaccins. Dans la deuxième période, ou « temps des campagnes » (1962–1985), ces vaccins sont utilisés à grande échelle pour des programmes d’éradication de la maladie. Les vaccins en culture cellulaire produits à Farcha sont en particulier utilisés lors de la campagne lancée par l’Organisation de l’Unité africaine (1962 1976) sous le nom de Programme conjoint n° 15. Ce programme aboutit à l’éradication temporaire de la peste bovine au Tchad. Malheureusement la persistance de foyers de la maladie dans plusieurs zones d’Afrique et l’arrêt des campagnes de vaccination au Tchad à la fin des années 1970 conduisent à son retour à partir de 1982. Suite au redémarrage de la production de vaccins en 1983 puis à la nationalisation du laboratoire en 1985, Farcha reste actif dans la lutte contre la peste bovine. Au cours de la troisième période, ou « temps de la surveillance » (1986–2007), le laboratoire contribue activement à la Campagne panafricaine contre la peste bovine (PARC), puis au Programme panafricain de contrôle des épizooties (PACE), notamment par des activités d’épidémiosurveillance et de sérosurveillance. Ces programmes conduisent à l’éradication définitive de la maladie dans la région. Depuis 2007, le Tchad est déclaré indemne de peste bovine, ce qui a contribué à l’augmentation rapide des effectifs bovins dans le pays et lui a ouvert des opportunités commerciales, surtout en matière d’exportation de bétail sur pied vers ses voisins.
SeMoDe – Simulation and Benchmarking Pipeline for Function as a Service
Authors: Manner Johannes
Published: December 2021

Cloud computing started with the promise of delivering computing resources elastically at scale, pay per use and on demand self-service to name a few capabilities. In early 2016, Amazon Web Services (AWS) launched a new product called AWS Lambda which started the so called serverless hype and established a new cloud delivery model, namely Function as a Service (FaaS). FaaS offerings keep the promise of delivering computing resources on demand. They dynamically scale up and down function instances and introduce the most fine-grained billing model across all as-a-service offerings by accounting on a milliseconds basis. Despite this flexibility and the possibility to concentrate on the business functionality, a FaaS user loses operational control. Only a few configuration options remain to tune the functions. The first pay-as-you-go billing model raises new questions for performance-cost trade-offs. In order to choose a suitable configuration dependent on the use case and get a solid understanding of performance impact of FaaS platforms, SeMoDe implements a benchmarking and simulation pipeline. It calibrates a physical developer machine, simulates the function in different settings which are comparable to those of cloud offerings and enables a decision guidance to choose an appropriate configuration when deploying it. Based on a Structured Literature Review (SLR) to show the benchmarking and simulation efforts, I suggest a checklist for conducting fair, repeatable and meaningful benchmarks with a focus on documenting the experiments.
Patient Adherence to Tuberculosis Treatment: A Relation between Family Support and Patient Behavior
Authors: Soleman Rani Putri Haji , Sukartini Tintin , Qona'ah Arina
Published: December 2021

Introduction: Knowledge, family support, and behavior have a significant impact on an individual's and community's health. They play a critical part in deciding disease control programs and transmission prevention of tuberculosis. The purpose of the study was to determine the association between family support, patient behavior, and tuberculosis treatment compliance in the Baing Primary Health Care of Wulla-Waijilu DistrictMethods:The study design was cross-sectional using the Spearman Rho test. The sample was 123 respondents with purposive sampling technique. The data collection was using sociodemographic questionnaires, family support, behavior, TB treatment adherence and MMAS-8. The dependent variable in this study was family support. The independent variables in this study were patient behavior and TB treatment adherence.Result:There was a relationship between family support and patient behavior (p=0.025), a relationship between family support and compliance with TB treatment (p=0.042)Conclusion:It can be concluded that there was a relationship between family support and TB patient behavior and there was a strong and significant relationship between family support and the level of TB treatment adherence.