bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of approaches to integrating microgrids into energy communities
Authors: Popova E. V. , Tomin N. V.
Published: July 2024

In this article, we set out to identify and analyze the key features of aggregating microgrids into energy communities, with a focus on the predominance of industrial or residential loads. Research methods included a literature review and meta-analysis in the field of planning, modelling and management of microenergy systems and their communities. In addition, a methodological approach combining multi-criteria decision-making methods and artificial intelligence was used. The efficiency of the approach was demonstrated by the establishment of two types of energy communities for remote settlements on the Sea of Japan coast, which integrated residential and industrial loads. The “Autonomous Operator” model, which involved a two-level optimization and reinforcement learning algorithm based on Monte Carlo tree search, was tested in order to determine the optimal economic management of operation modes of the potential energy community. At the lower level, the problem of finding market equilibrium was solved by minimizing the function of total operating costs. At the upper level, the management strategy that provides the optimal profit distribution among the community members was selected. Two scenarios of microgrid integration and operation in an energy community were studied: industrial and public types. The research demonstrated that operating settlements as energy communities is a more economically and ecologically advantageous approach than operating them individually. The results indicated that the levelized cost of electricity (LCOE) decreased more significantly when combining settlements in an industrial-type energy community (from 22 rub/kWh to 6 rub/kWh) compared to a public-type community (from 22 rub/kWh to 9 rub/kWh). The analysis of the above characteristics of different types of energy communities can help designers to determine the possibilities, features and consequences of aggregating microgrids of different types under various territorial and climatic conditions.
Challenges of ensuring the integration of internally displaced persons into host communities: Behavioral determinants
Authors: Voznyak Halyna , Storonyanska Iryna , Mulska Olha , Patytska Khrystyna , Kaspshyshak Andriy
Published: July 2024

Internal migration caused by the war of russia against Ukraine (with the active phase starting in February 2022) has increased the socio-economic burden on the host communities welcoming internally displaced population from the frontline and occupied territories. On the other hand, it intensifies behavioral reflections of local residents on the integration of internally displaced persons (IDPs). The study aims to identify opportunities, challenges, and prospects for IDPs’ adaptation in host communities (a case study of Lviv oblast, Ukraine). The paper conducted a sociological survey among 2,500 respondents in November 2022–February 2023. The results show that the lack of housing, lack of permanent employment, language contradictions, and forced limited contact with relatives who remain in the combat zone are existential barriers to the integration of IDPs into host communities. The study identified such opportunities for the integration of IDPs into the host society: reducing the risk of depopulation of territories, reducing imbalances in the local labor market in certain sectors of the economy, strengthening social cohesion, developing small businesses, and improving social infrastructure. The respective challenges include increased social tension, competition for jobs and housing, shortage of places in preschool institutions, and disproportionate distribution of budget funds between the local population and IDPs. Conflicts between IDPs and local residents, as well as IDPs and local authorities, require a proactive position of local authorities to initiate psychological support programs and create communication platforms for the exchange of individual experiences and discussion of psychological and emotional issues.
EXPLORING THE LINKS BETWEEN AFFECT AND DRIVER BEHAVIOR: A SYSTEMATIC REVIEW
Authors: Azık Özkan Derya
Published: June 2024

Driving, as a multifaceted daily task, is intricately intertwined with our emotional states. However, the integration of affective states into driving research is conspicuously lacking in the existing literature. The primary goal of this study is to systematically examine and elucidate the relationship between these affective states and driving actions, with a particular focus on driving behavior. The review synthesizes findings from 21 articles that specifically address the interplay between emotional states and driving behaviors. Despite the complexity and variability of the relationship between emotional states and driving, the review highlights that both positive and negative affect are associated with risky and reckless driving behaviors. The synthesis of findings presented in this review serves as a comprehensive and holistic overview of affect-integrated driving studies. Based on the findings, future intervention techniques, such as in-vehicle assistance systems, could be developed to assist drivers in managing their emotional states while driving.
The Influence of the Posonan Tradition at the Pathok Negoro Mlangi Mosque on Mad'u Behavior
Authors: Imawan Dzulkifli Hadi , Al Ghazali Muhammad Nurkhalid
Published: June 2024

The Pathok Negoro Mosque is one of the mosques that plays an important role in maintaining the religious understanding of the surrounding community. This mosque is a cultural heritage protected by the Yogyakarta government. In the month of Ramadhan (Posonan) this mosque has a religious tradition in the form of a yellow book study filled by local scholars who are scheduled every afternoon and evening. Therefore, this research needs to be carried out to explore the Posonan religious tradition in the Pathok Negoro Mlangi Mosque and its influence on religious understanding in the surrounding community. This research includes descriptive qualitative with a historical approach to reveal the content of the object under study. Posonan religious traditions at the Pathok Negoro Mlangi Mosque have influenced the mad’u in community that increasing the spirit of increasing worship, the spirit of studying, and the spirit of having Islamic character as well as strengthening social ties and a sense of responsibility.
Walisongo Da'wah Strategy: Analysis of the Symbolism of Amar Ma’ruf Nahi Munkar in Semar and Togog Characters
Authors: Hidayatullah Ahmad
Published: June 2024

The Spreaders of Islam in the early period -Walisongo- used wayang (puppet), which is very thick with symbolic values as a media of da’wah, and two of those are in the character of Semar and Togog. Both Semar and Togog have a crucial position in Javanese Wayang's story, which are used as a strategy to make Islamic teachings reachable in society. By using a qualitative descriptive method, this study explores how the symbolic representation of amar ma’ruf nahi munkar in the construction of Semar and Togog characters. The result of this study that Semar as a guardian of protagonist character, such as Pandawa is a representation of amar ma’ruf. On the other side, Togog, the guardian of giants and other antagonist characters, is represented symbolically as nahi munkar. Nevertheless, the Togog’s position, which is in the part of antagonist does not make him automatically become an antagonist itself. He even has a more challenging and more glorious role than Semar because he must be in the dark circle without being a part of that dark itself.
Evaluation of Quality Services at PT. Hajar Aswad Mubaroq
Authors: Dani Akhmad Anwar , Gemelli Teha Aulia , Sativa Alfiana
Published: June 2024

This study aims to determine the quality of services provided byPT. Hajar Aswad Mubaroq to the congregation; to find out theobstacles faced in the implementation of Umrah plus Turkish worship,and to evaluate the services provided by the bureau to thepilgrims. Using qualitative research methods with descriptive analysistechniques. The main data were obtained through interviews withemployees and the study of related documents. It was concluded thatPT. Hajar Aswad Mubaroq has done a good service to thecongregation from departure to return home. So that the results of theevaluation of the services of PT. Hajar Aswad Mubaroq was verysatisfying for the congregation. Obstacles faced when carrying outUmrah and tours in Turkey, sick pilgrims, lost pilgrims and late pilgrimsand elderly pilgrims.
Implementation of Management Functions in Economic Recovery in the Tourism Village of Babalan Lor Village
Authors: Haikhal Fikri , Irawan Soni , Maulana M. Mirza , Hidayatullah Ahmad
Published: June 2024

This article was written to find out about the implementation of the economic recovery management function in the tourist village of Babalan Lor Village, Bojong District. Hence, the information can be deciphered regarding the implementation of economic recovery carried out by the residents of the tourist village in Babalan Lor Village. The problem of this study was how the strategy was applied by the tourism village community in recovering the economy through the management function. The method used in this study was a qualitative approach as the qualitative components include observation, interviews, and literature research. The results of the study showed that the residents of tourist village carry out a management function; they are the principles of planning, organizing, actuating and controlling as a strategy in recovering the economy.
The Influence of Infaq and Shodaqoh Fundraising on Donors’ Satisfaction at Lazis MD UIN Jakarta
Authors: Sabela Arifah Putri , Ibnugraha Muhammad Ilgham , Hamdi Muhammad Samman , Zaman Ahmad Munawaru
Published: June 2024

The fundraising activity conducted by LAZIS MD (Laboratory of Amil Zakat Infaq Shodaqoh of Da’wah Management) was a learning medium carried out by UIN Jakarta students in the Da’wah Management study program, Faculty of Da’wah and Communication Sciences in the Fundraising Management course. It was different from zakat institutions that are official and recognized by zakat institutions in Indonesia. It was called a laboratory because it was a learning medium, not an official institution and was not included in the category of fraudulent institutions. The problem in this laboratory was whether it had given satisfaction to the donors in terms of service, management, and the system. From the issues above, it could be emphasized that the formulation of the main problem in this research was how was the influence of infaq shodaqoh fundraising on donor satisfaction at LAZIS MD UIN JAKARTA? The purpose of this research was to find out if the program could be achieved adequately, could increase donors, and increase donors’ satisfaction. As an analytical tool, this study used a descriptive quantitative method, using a purposive sampling technique, in which the researcher took samples from all donors of LAZIS MD UIN Jakarta who matched their characteristics (100 people). The research instrument used a Likert Scale, to measure attitudes and opinions. The data collection technique used in this study was by filling out a questionnaire. This research provided an answer that donors were satisfied with the fundraising of infaq and shodaqoh carried out by LAZIS MD UIN JAKARTA. It could be proven by obtaining a score of 88.33% which of the 100 people who filled out the questionnaire, there were 75 people who chose the satisfied category.
The Effectiveness of SISKOHAT in Organizing Hajj at the Ministry of Religious Affairs Office of Lima Puluh Kota Regency
Authors: Qolbi Lora , Rahman Ali
Published: June 2024

The Ministry of Religious Affairs Office of Lima Puluh Kota showed that the number of employees who could use SISKOHAT was only three people; hence, if many pilgrims registered on the same day, the employees at the Ministry of Religious Affairs Office of Lima Puluh Kota would have difficulty serving the pilgrims. The pilgrims would take a long time waiting in line. The research method used in this study was a qualitative descriptive approach. Data collection techniques were by observing, interviewing, and documentation. The participants in this study were employees of theMinistry of Religious Affairs Office of Lima Puluh Kota and one of the pilgrims who came to the Ministry of Religious Affairs Office of Lima Puluh Kota. The analytical method in this study started with data collection, data reduction, and drawing conclusions. The results of the study showed that SISKOHAT was running well, and system updates were being carried out in line with increasingly advanced technological developments in organizing the pilgrimage at the Directorate General of PHU at theMinistry of Religious Affairs Office of Lima Puluh Kota. The inhibiting factor of SISKOHAT that occurred at the Ministry of Religious Affairs Office of Lima Puluh Kota did not become a barrier for the staff of the Hajj and Umrah pilgrimage division. In addition, the government also anticipated so that it could prevent incidents that could hinder the effectiveness of information and computerized systems.
Implementation of Hajj Manasik Guidance Management at the Ministry of Religious Affairs Office of Sragen Regency
Authors: Novitasari Hesty , Yuliar Ade
Published: June 2024

The research aims to determine the general description of the implementation of Hajj ritual (manasik) guidance by the Ministry of Religious Affairs of Sragen Regency for prospective Hajj pilgrims. The research was descriptive qualitative with data collection techniques through observation, interviews, and documentation. The results showed that the implementation of guidance on mass Hajj manasik of the Ministry of Religious Affairs of Sragen Regency was aligned with the planning that had been formed and in accordance with the Decree of the Director General of Hajj and Umrah Implementation No. 164 of 2023 concerning guidelines for organizing Hajj manasik guidance for regular pilgrims at the Regency or City and District levels. The Ministry of Religious Affairs of Sragen Regency used four management functions in carrying out Hajj manasik guidance activities: planning, organizing, implementing and supervising.
Implementation of the Mosque Management Information System (SIMAS) in Improving Services at the Ministry of Religious Affairs Office Kendal Regency
Authors: Dika Muhammad , Hakim Lukmanul , Susanto Dedy
Published: June 2024

The SIMAS (Mosque Management Information System) application from the Indonesian Ministry of Religious Affairs is used to manage data on mosques and musallas online throughout Indonesia. This research used a descriptive qualitative method with data collection techniques in the form of interviews, observation, and documentation. The results of data analysis showed a significant increase in services at the Ministry of Religious Affairs Office due to the use of SIMAS. The previous manual data collection on mosques and musallas (musallas) has been replaced with an online method via the SIMAS website with collaboration between various agencies, including the Office of Religious Affairs and sub-districts. It has accelerated and improved effectiveness of services in the office. With adequate human resources, SIMAS has become an efficient tool for inputting data on mosques and musallas. This research highlights the important role of SIMAS in improving efficiency and service at the Kendal Regency Ministry of Religious Affairs Office.
Risk Analysis of Information Technology Using Si Semar Layak in Online Umrah Passport Registration
Authors: Savitri Fania Mutiara , Fadhilah Savira Maghfiratul , Silva Nilta Fidya , Neha Saniya Ovin , Albana Hifni Syauqi , Taqiyyudin M. Aufa
Published: June 2024

This study aims to identify potential risks and provide a foundation for developing effective mitigation strategies. The research employed a qualitative approach to analyze information technology risks in online Umrah passport registration. Data collection was conducted through interviews, observations, and documentation. The analysis revealed that risks in online passport registration for Umrah pilgrims include data security risks, system vulnerability risks to cyber-attacks, network infrastructure failure risks that could disrupt online access, data processing errors risks, and application vulnerability risks to hacking. Mitigation measures include enhancing data security through encryption and strong access control, implementing appropriate security measures to reduce cyber-attack risks, conducting regular data backups to anticipate system failures, improving staff training and awareness on data processing, and performing regular security updates.
Constitutional Law Enforcement and the Direct Effect of the Constitution: Issues of Correlation
Authors: Samusevich A. G. ,   Irkutsk Institute (Branch), All-Russian State University of Justice
Published: July 2024

This article raises the question of the relevance and importance of constitutional law enforcement in the Russian legal system. The imperfection and lack of knowledge of the mechanism of constitutional law enforcement and its main components are indicated. In addition, an author's attempt is being made to correlate constitutional law enforcement and the direct effect of the constitution. To achieve this goal, the article analyzes various scientific approaches of such legal categories as "direct effect of the constitution" and "constitutional law enforcement". Their definitions are formulated and the main features, as well as problematic aspects of understanding in domestic jurisprudence, are identified. The author comes to the conclusion that the direct effect of the constitution, first of all, acts as a property, and to some extent as a principle of the constitution. In turn, constitutional law enforcement is a broader phenomenon, which is a form of implementation of articles of the constitution. At the same time, according to the results of the study, a thesis is formulated according to which the direct effect of the constitution and constitutional law enforcement relate to each other as general and particular, as a whole and a part. In general, it is concluded that constitutional law enforcement is a dynamic element of the direct operation of the constitution, ensuring the implementation of its norms.
Detection of English Grammatical Errors and Correction using Graph Dual Encoder Decoder with Pyramid Attention Network
Authors: Hema M ,   KPR Institute of Engineering and Technology, Coimbatore, India., Sellamuthu Kandasamy , Vijayarajeswari R
Published: July 2024

In English, grammatical errors pose a significant challenge, prompting the exploration of diverse detection and correction methods. Existing approaches, however, often fall short of delivering satisfactory results and achieving high accuracy. An innovative solution, the Optimized Graph Dual Encoder Decoder with Pyramid Attention (OGDED-PA), is introduced to overcome these limitations. The model utilizes the C4_200M synthetic dataset for input data, followed by preprocessing and applying hybrid Squared Root of Term Frequency Variants with Mean Semi-absolute Deviation Factors for morphological feature extraction. Bidirectional long short-term memory with conditional random field segmentation is employed, and OGDED-PA, integrating a dual encoder-decoder architecture and pyramid attention mechanism, is then applied. This model aims to enhance accuracy in identifying and correcting grammar, syntax, punctuation, and spelling errors by capturing intricate linguistic patterns. The graph-based representation leverages Improved Border Collie Optimization (IBCO) to optimize the weight parameter, allowing the model to analyze syntactic and semantic relationships and address a broad spectrum of grammatical errors. The proposed method is implemented using the Python platform. Compared to existing methods, the proposed approach achieves 99.3% accuracy, 98.7% precision and 98.6% F0.5.
Biosorption of antimony using tea leaves and tea fibers (Camellia sinensis) as adsorbents: thermodynamics, isotherm, and kinetics
Authors: Etim Emmanuel ,   Federal University Wukari, Taraba State, Nigeria, Yakubu Shedrach , Okafor Richard , Bako Bulus ,   Federal University Wukari, Taraba State, Nigeria,   Federal University Wukari, Taraba State, Nigeria,   Federal University Wukari, Taraba State, Nigeria
Published: July 2024

Rapid industrial development causes environmental contamination of land, water, and air with heavy metals which pose a significant threat to human survival. This study aims to remove antimony from wastewater using tea leaves and tea fiber (Camellia sinensis) as an adsorbent to curb the environmental decay posed by industrialization. The FTIR study presents significant vibration frequencies that correspond to –OH, C-H, and C=O in both the leaves and fibers which impact the adsorption. The adsorption study was performed by the batch adsorption method, varying different parameters including pH, adsorbent dosage, temperature, initial concentration, and contact time to find best-suited conditions for the removal of antimony from aqueous media. The results show an equilibrium condition at pH 5 and 30 minutes for both tea leaves and fibers whereas for tea leaves the equilibrium concentration was obtained at a dosage of 2g, and 3g for the fiber. From the adsorption model, the sorption of antimony by tea leaves follows the Langmuir model (R2 = 0.783), whereas that of tea fiber follows Freundlich (R2 = 0.827). From Kinetic studies, the sorption of antimony by both plant parts follows second-order kinetics with approximate R2 values of 1. From the adsorption capacity, it is no exaggeration to consider tea leaves and fibers as an excellent biosorbent for the sorption of antimony.
Pilot scale advanced photo-oxidation processes for remediation of pharmaceutical wastewater. A case study
Authors: Sheth Sujitraj ,   National Key Laboratory of Green Pesticide, Guizhou University, Guiyang, China, Wang Bin , Rehman Atta Ur ,   National Key Laboratory of Green Pesticide, Guizhou University, Guiyang, China,   College of Life Sciences, Guizhou University, Guiyang, China
Published: July 2024

The investigation of photochemical degradation of chemical components in pharmaceutical wastewater by use of ultraviolet (UV) irradiation, UV in combination with sodium hypochlorite (UV/NaOCl), and Fenton’s reagent (UV/H2O2/Fe2+) was performed. Objective of this study was to determine the best alternative to the conventional wastewater treatment or pre- / post-treatment in combination with biological treatment to one of the four effluent source outlets. The effect of the advanced oxidation treatments provided varying degree of COD reduction for all four effluents. The results showed UV/H2O2/ Fe2+ treatments provided maximum chemical oxygen demand (COD) reduction of the anaerobic system outlet effluent. The combination of UV/H2O2/ Fe2+ (750 mg/L FeSO4+7500 mg/L H2O2) provided reduction in COD up to 75% upon three-hour UV exposure. The initial effluent COD was about 22000 mgO2/L and the treated effluent BOD5 /COD ratio was 0.50 showing greater amenability to biological processes. Sodium hypochlorite dosages between 3000 and 10000 mg/L achieved the results with little variation as compared to UV/H2O2/ Fe2+. Additionally, comparison was made of the UV exposure time required to reach the maximum reduction of COD value and the necessary effective oxidant dose to achieve the desired COD reduction, which could provide predictive model for the treatment of wastewater processes.
Comentario de jurisprudencia: efectos de la aprobación del acuerdo de reorganización respecto del acreedor garantizado con cauciones personales que votó en contra de la propuesta de acuerdo. Notas a propósito de dos sentencias recientes
Authors: Ortiz Solorza Mauricio
Published: June 2024

El presente trabajo está dedicado a comentar críticamente dos sentencias, relativamente recientes, dictadas por la Primera Sala de la Excma. Corte Suprema, sobre los efectos que produce la aprobación del acuerdo de reorganización respecto del acreedor garantizado con cauciones personales que votó en contra de la propuesta de acuerdo. Lo anterior resulta de especial interés, atendida la omisión del legislador en relación a los efectos que se producen respecto del acreedor garantizado que, manifestando su voto, lo hace en contra de la propuesta de acuerdo de reorganización.
importância da informação em rótulos de produtos da indústria cosmética
Authors: Mota Francisca Rosaline Leite , Pereira Monalisa de Oliveira , Camargo Vanessa Zaclikevic
Published: July 2024

A oferta e demanda por produtos cruelty free é tema de destaque na contemporaneidade. As informações disponibilizadas nos rótulos de produtos devem ser bussólas a guiar o consumidor na hora da compra. O objetivo da pesquisa foi  estudar se o acesso a informações nos rótulos de produtos cosméticos influencia a decisão de compra. A metodologia adotou a pesquisa exploratória com abordagem qualitativa. O universo de pesquisa foi formado por consumidores que adquirem produtos em três grandes redes de atacado e varejo do município de Maceió, capital do estado de Alagoas. A amostra foi aleatória e o instrumento de coleta de dados utilizado foi um Formulário do Google Forms. A coleta dos dados foi realizada no período de outubro a dezembro de 2023 e contou com a participação de 138 participantes. Os resultados mostraram baixo percentual de respondentes (33,6%) que afirmaram realizar a leitura das informações dos rótulos antes de comprar os produtos. 46% dos respondentes afirmaram que dariam preferência ao consumo de produtos que tenham o selo cruelty free e 48% afirmaram que dariam preferência ao consum destes produtos a depender do preço praticado. Os dados revelaram que, mesmo ainda tímida, há uma adesão aos produtos cruelty free.
Unraveling of Potential Targets for Andrographolide, Neoandrographolide and 5-hydroxy, 7-methoxy Flavone in the Treatment of Rheumatoid Arthritis using Network Pharmacology and Molecular Docking
Authors: Rana Neha , Grover Parul , Singh Hridayanand , Rastogi Sameer , Chawla Pooja A.
Published: July 2024

:

Joint degeneration is a possible outcome of rheumatoid arthritis, an inflammatory disorder that is
chronic, systemic, and progressive. Andrographis paniculata is known to contain many phytoconstituents that
have demonstrated therapeutic effects in terms of inflammation. However, the therapeutic actions of Andrographis paniculata are still not fully understood. The present study aims to better understand rheumatoid
arthritis and its possible treatments through the identification of relevant targets and mechanisms. A total of 47
common targets were identified for andrographolide, while 38 common targets were found for neoandrographolide. Additionally, 53 common targets were discovered for 5-hydroxy-7-methoxy flavone. Furthermore,
a screening process was carried out to identify 9 primary hubb targets for andrographolide, neoandrographolide, and 5-hydroxy-7-methoxy flavone. Twenty useful gene ontology (GO) terms and twenty important
Kyoto Encyclopaedia of Genes and Genomes (KEGG) pathways were found through the study of gene ontology and pathways. Molecular-docking analysis revealed that andrographolide had the highest binding efficacy (-
7.8) towards the Serine/threonine-protein kinase 2 (PIM2) target. On the other hand, neoandrographolide displayed the highest binding efficacy towards mitogen-activated protein kinase (MAPK1) and Interlukine-6 (IL6), with docking scores of (-9.0) and (-7.2), respectively. Furthermore, 5-hydroxy-7-methoxy flavone showed
the highest docking score (-6.6) with Arachidonate 12-lipoxygenase (ALOX-12). The identification of numerous targets linked with various pathways in the treatment of Rheumatoid arthritis proves to be a helpful resource for future investigation into the mechanism and clinical applications of AP, NP, and 5H-flavone.
Chemical Compositions, Antimicrobial and Therapeutic Properties of
Essential Oils of Dennettia Tripetala
Authors: J. Ekandem Joachim , A. Udourioh Godwin , K. Obi Leonard , Solomon Moses M.
Published: July 2024

Background:

It is well-known that essential oils are a rich source of bioactive components and are traditionally used as one of the alternatives to conventional medicines for treating various diseases and symptoms. Like other natural products, they are safe but should be used with care
since all substances have potential toxicity depending on the conditions of exposure, the dose, and
the route of administration.

Method:

This manuscript studies the chemical composition and antimicrobial properties of essential
oil derived from D. tripetala. The essential oil was extracted from fresh D. tripetala fruits using
steam distillation and subsequently subjected to Fourier Transform Infrared Spectroscopy (FT-IR)
and Gas Chromatography with Flame Ionization detection (GC-FID) analyses. The antimicrobial
potential of the essential oil was evaluated against a panel of microorganisms, namely Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Salmonella typhi, Klebsiella pneumoniae, Pseudomonas aeruginosa, Candida albicans, and Aspergillus niger.

Results:

The GC-FID analysis unveiled a diverse array of compounds within the essential oil, with
the notable constituents being linalool, benzyl nitrile, benzene (2-nitroethyl), bicyclo(4.2.0)octa1,3,5-triene, 1,3,7-Octatrien-5-yne, styrene, butylated hydroxytoluene, and Nerolidol 2. D. tripetala
essential oil significantly inhibits the microbial activities of all the tested organisms. It exhibits inhibitory activity against Bacillus subtilis and Escherichia coli at a MIC value of 12.5%, Staphylococcus
aureus, and Pseudomonas aeruginosa at a MIC value of 25%, Candida albicans at a MIC value of
50%, and Aspergillus niger at MIC value 25%. The strongest inhibition of the oil is against Klebsiella pneumoniae at a MIC value of 3.12%.

Conclusion:

This research posits that the ethnomedicinal value ascribed to the essential oil of D.
tripetala can be attributed to the presence of the identified compounds, some of which are already
recognized for their biological activities. The essential oil presents promising potential as a source of
lead compounds for developing anti-infective drugs, particularly those targeted against Klebsiella
pneumoniae
Exercise Alters FBF1-Regulated Novel-miRNA-1135 Associated with Hydrolethalus Syndrome 1 in Rheumatoid Arthritis: A Preliminary Study
Authors: Tansathitaya Vimolmas , Sarasin Witchana , Phakham Tanapati , Sawaswong Vorthon , Chanchaem Prangwalai , Payungporn Sunchai
Published: July 2024

Background:

Hydrolethalus Syndrome 1 (HYDS1) is a rare disorder that occurs commonly in Finnish infants but originates from the mother. This autosomal recessive syn-drome is associated with the FBF1, which is usually expressed in the centriole. The FBF1 is an inheritable arthritis disease phenotype that includes rheumatoid arthritis. Several studies have investigated males with FBF1 mutation carriers also related to arthritis diseases, including those under rheumatoid arthritis conditions, which revealed the possibility of conferring the gene mutation to the next generation of offspring. Nonetheless, there are some complications of FBF1 mutation with target miRNAs that can be affected by exercise.

Objective:

The objective of this study was to evaluate the different exercises that can be utilized to suppress the FBF1 mutation targeted by Novel-rno-miRNAs-1135 as a biomarker and assess the effectiveness of exercise in mitigating the FBF1 mutation.

Methods:

Four exercise interventional groups were divided into exercise and non-exercise groups. One hundred microliter pristane-induced arthritis (PIA) was injected at the dorsal re-gion of the tails of rodents and introduced to the two PIA interventional groups. On day forty-five, all animals were euthanized, and total RNA was extracted from the blood samples of ro-dents, while polymerase chain reaction (PCR) was amplified by using 5-7 primers. Computeri-zation was used for miRNA regulation and analysis of target gene candidates.

Results:

The novel-rno-miRNA-1135 was downregulated to FBF1 in exercise groups. The exercise was found to have no significant impact in terms of change in novel-rno-miRNA-1135 regulation of FBF1 expression.

Conclusion:

Exercise has no impact on novel-rno-miRNA-1135 targeted for FBF1 in autoso-mal recessive disease.
Public railway depot maintenance and maintenance work based on work breakdown structure (WBS) to improve maintenance and maintenance performance
Authors: Fakrunnisa Iffah Ariqoh , Latief Yusuf , Wardahni Nurul Inayah
Published: June 2024

Maintenance and upkeep of railway facilities is important to reduce the risk of work accidents. However, in some cases, there is equipment that is damaged and the equipment is very old. This is due to a lack of attention to public railway depot maintenance and maintenance work. This research discusses the evaluation of financing for maintenance and upkeep work, where in reality in the field, many railway maintenance facilities cannot be used properly due to negligence in the maintenance process. The aim of this research is to improve the maintenance and maintenance performance of railway depots in the aspects of structural buildings, rails and equipment supporting maintenance of railway facilities. The method used in this research is a literature review, case study, and survey conducted by distributing questionnaires to several experts, namely those carrying out maintenance activities at PT Kereta Api Indonesia (Persero), PT LRT Jakarta, and several sources who participated in the construction of the railway depot. The results of this research are the WBS of maintenance and upkeep work which is used to improve the maintenance and maintenance performance of railway depots.
De tesis a libro. Guía para la escritura de libros académicos.
Authors: Germaro William
Published: July 2024

De tesis a libro: guía para la escritura de libros académicos ofrece claves fundamentales para los autores académicos y reconoce el gran esfuerzo que hay detrás de la escritura de una tesis doctoral. El libro recorre los procesos editoriales, da luces sobre el pensamiento de los editores académicos y genera importantes reflexiones sobre los lectores y las audiencias. Todo ello para guiar a los autores interesados en divulgar sus aportes científicos hacia un propósito clave: producir libros para un público lector. Es también un texto muy útil para editores tanto profesionales como en formación, para profesores de pregrado y posgrado que quieran mejorar sus habilidades de escritura y, a su vez, trabajar de la mano con sus estudiantes, y para quienes quieran que el conocimiento científico trascienda las fronteras de la academia y llegue a audiencias mucho más amplias.
Impact Chain Analysis on Determining the Vulnerability Levels of Women to Climate Hazards and Risks: A Case Study of Türkiye
Authors: Eren Zeynep , Toy Süleyman
Published: June 2024

The case studies in the literature and the reports prepared by international organizations indicate that the vulnerability level of women to climate change-related hazards and risks is considerably high. In addition, it is mentioned in the literature that women’s participation in both the development and implementation of mitigation and adaptation actions to be taken against climate change will yield more positive outcomes. It is seen when considered the impact chain analyses described in the reports of the Intergovernmental Panel on Climate Change (IPCC) that there is still a need to propose methods and data sets which involve the transformation of the required parameters to be used for the determination of women’s vulnerability levels to climate change under specific factor groups into data and the determination of the vulnerability levels through concrete indicators by weighting these data. Therefore, the aim of this study is to propose parameters, data, and data sources that can be used in the impact chain analysis of women’s vulnerability in Turkey using the methodology developed to analyse the vulnerability of various sectors and themes to climate change. For this purpose, a methodology combining the PESTEL technique, initially used in the external environmental analysis of private sector companies, with the impact chain analysis conducted within the scope of climate change to determine the parameter classes in the most comprehensive way and a data set is described to contribute to the modelling studies that provide concrete and comparative insights into the women’s vulnerability to climate change.
Virginia Woolf s A Room of One s Own: A Foundational Feminist Vision in Euro-American Thought
Authors: Krupa Henrieta
Published: June 2024

Virginia Woolf’s seminal work, A Room of One’s Own, published nearly a century ago, is reexamined in this study as not only a feminist manifesto but as a feminist vision that anticipated some of the key features addressed in subsequent Euro-American feminist philosophies. Divided into three sections, the research offers a close analysis of Woolf’s text and its prescient insights, discussing separately the particular focal concerns of British, American, and French feminism, and elaborating on the ways these were envisioned and addressed as early as 1929 in Woolf’s visionary text. The study utilizes Showalter’s typology to analyze Woolf’s text and to organize elaborations on the points Woolf addresses and envisions that became fundamental within subsequent Euro-American feminist criticism, including the correlation between economic and social conditions and intellectual freedom, the necessity of women’s inclusion in the literary canon, and the significance of feminine discourse and gynocriticism. By highlighting Woolf’s remarkable foresight, this research positions A Room of One’s Own not only as a foundational feminist text but also as a profound feminist vision that continues to inform feminist thought today. This re-examination of Woolf’s work contributes to on-going academic discourse surrounding feminist theory and literary criticism.
Bir Dindarlaşma ve Muhafazakârlaşma Örneği: Sonradan Tesettüre Giren veya Başörtüsü Takan Kadınlar Üzerine Sosyolojik Bir Araştırma
Authors: Tunç Harun , Ünlü Ceydanur
Published: June 2024

Modernleşme süreciyle ‘din’ kavramı daha durağan konumlandırılırken ‘sekülerleşme’ ise akışkan ve dalgalı bir süreç olarak konumlandırılmıştır. Buna bağlı olarak da sosyolojik literatürde sürekli sekülerleşme örnekleri çalışılmıştır. Örneğin, sonradan başörtüsü takmayı bırakan örneklem üzerine pek çok çalışma yapılmıştır. Fakat bu süreçte dinin de akışkan ve gelgitli olabileceği, dindarlaşma ve muhafazakârlaşmaya dair çeşitli örneklerin de olabileceği genellikle göz ardı edilmiştir. Bu çalışmada sonradan tesettüre giren veya başörtüsü takan kadınların dindarlaşma ve muhafazakârlaşma eğilimleri sosyolojik perspektiften ele alınmıştır. Toplam 25 kadın ile derinlemesine görüşme yapılmıştır. Örneklemin çoğunluğu lisans öğrenimi düzeyindeki örneklerden oluşmaktadır. Örneklemin ilk kez tesettüre girme veya başörtüsü takma yaş ortalaması da 26’dır. Çalışma böyle bir örneklem grubunu ilk kez ele alan bir çalışma olması dolayısıyla da ayrı bir özgünlüğe sahiptir. Araştırmanın elde edilen bulgularına göre sonradan tesettüre giren kadınlarda dini hayatın merkezine alan bir dindarlaşma biçimi ve gündelik yaşam pratiklerinde meydana gelen değişimlere bağlı bir muhafazakârlaşma biçimi kendini açıkça göstermektedir.
Kapitalizmin İcadı Uysal Bedenler: Şeytan Marka Giyer Filminde Kadın Temsilleri
Authors: Uğurel Özdemir Ebru
Published: June 2024

Erkek egemen toplumlarda hayatta kalabilmek adına çok az seçeneği olan kadının, bilinçaltına işlenmiş kader algısını yıkmak kolay olmamıştır. Kadın, çoğu zaman utandırıldığı bedeni ile var olabilmek, bu beden yazgısında varlık gösterebilmek için bazı ideolojik silahların hedefi olmuştur: erken dönem Freudyen psikanaliz ve kapitalizmin birbirini besleyen güçleriyle dayattıkları pek çok asılsız söylem, kadın bedenini ve aklını uysallaştırmaya çalışmaktadır. Bir nevi yatırım olarak görülen beden, onu en kusursuz hale getirmek için kadına bir sorumluluk olarak yüklenmektedir. Bu çalışmanın amacı, kadının ve kadın bedeninin ideolojik güçlere karşı savunmasızlığını, psikolojik ve fiziksel olarak maruz kaldığı baskıyı, görsel bakımdan çok daha etkili bir örneklendirme sağlaması niyetiyle Şeytan Marka Giyer filmiyle yorumlamaktır. Söz konusu film, tanınmak ve var olabilmek için kendisinin yaratmadığı kategori, kavram ve adlara bağlanmak zorunda kalan kadının, her türlü ideolojik oyuna tabi olmak durumunda kalmasını etkili biçimde örneklendirmektedir. Bu çalışmada, kadın bedeninin tarih boyunca taşıdığı anlamlar özetlenecek olup; kadın psikolojisini olumsuz yönde etkileyen bilinçaltı ve ideoloji ilişkisi açıklanacaktır. Kapitalist sistemin ataerkil düzenle birlikte kadın bedenine karşı açtığı savaş, Foucault’nun ileri sürdüğü iktidar anlayışıyla bağdaştırılacak; ‘uysal bedenler’ ve ‘panoptikon’ kavramları çerçevesinde sınıflandırılacaktır. Bu münasebetle, Şeytan Marka Giyer filmindeki iki kadın karakterin eylemleri ve yaşadıkları olaylar sözü geçen kavramlar bazında ele alınacaktır. Tüketim ideolojisinin ve popüler kültürün bir yansıması niteliğinde olan Şeytan Marka Giyer filmi aracılığıyla medyanın kadını sömüren rolü ve etkisi de örneklerle açıklanacaktır.
RESULTS OF THE STUDY OF THERAPEUTIC PATHOMORPHOSIS OF MALIGNANT EPITHELIAL TUMORS IN PATIENTS WITH LOCALLY ADVANCED RESECTABLE COLON TUMORS UNDER PREOPERATIVE CHEMORADIATION INDUCTION
Authors: Teren T. I. , Partykevych Yu. D. , Hrytsyk R. A.
Published: June 2024

Оцінка лікувального патоморфозу є вагомим показником у цілому для визначення ефективності використаного лікування в доопераційному періоді та покращення резектабельності солідних пухлин епітеліального походження з локалізацією в ободовій кишці. Метою дослідження – вивчення ефективності внутрішньовенного введення 5-фторурацилу й одночасного крупнофракційного опромінення пухлини в неоад’ювантному режимі у хворих на резектабельний рак ободової кишки. Застосування хіміопроменевого компонента лікування на доопераційному етапі має певні впливи на структуру пухлинного осередку та викликає множинні парціальні некрози в пухлині, а також незворотні зміни в ній, що сприяє надалі абластичності проведення оперативного втручання, зменшує ризик місцевого рецидиву захворювання та покращує резектабельність пухлинного процесу.
Мета. Вивчення особливостей лікувального патоморфозу, зумовленого неоад’ювантною хіміопроменевою терапією у хворих на місцево поширений рак ободової кишки на базі КНП «ПКОЦ ІФ ОР».
Матеріали та методи. Групу спостережень становили 90 хворих на місцево поширений рак ободової кишки (РОК).
Усі хворі розподілені на групи таким чином: І група – хворі на місцево поширений РОК, які отримували курс неоад’ювантної хіміопроменевої терапії (НеоАХПТ) з наступним хірургічним лікуванням (ХЛ) і ад’ювантною хіміотерапією (АХТ) за показами, – 43 пацієнти;
ІІ група – хворі на місцево поширений РОК, яким проведено хірургічне лікування й АХТ за показами, – 47 пацієнтів.
Результати. Зіставлення морфологічних проявів лікувального патоморфозу з клінічними даними показало, що ступінь їхньої вираженості співпадала з об’єктивно реєстрованим клінічним ефектом, тобто за морфологічними ознаками постало за можливе судити про чутливість пухлини до передопераційного хіміопроменевого лікування.
Висновки. Обов’язкове морфологічне дослідження злоякісних пухлин ободової кишки дозволило узагальнити отримані результати аналізу їх лікувального патоморфозу за структурними ознаками девіталізації пухлинних клітин наявності, зокрема, патологічних мітозів для визначення ефективності неоад’ювантних (передопераційних) методів терапії хворих на місцево поширений рак ободової кишки.
ANALYSIS OF NEOADJUVANT TREATMENT OF HORMONE-DEPENDENT FORMS OF BREAST CANCER (STAGE I-III): RETROSPECTIVE ANALYSIS
Authors: Ivkov S.M. , Andriiv F.V. , Stinskyi Yu.V. , Zhukovych A.S. , Dmytrenko I.A. , Kryzhanivska A.E.
Published: June 2024

Рак грудної залози є одним із найбільш розповсюджених злоякісних захворювань у жінок у світі. Відповідно актуальність цієї теми зумовила проведення аналізу зв’язку РГЗ із гормонами, доцільністю неоадʼювантного впливу хіміотерапевтичними препаратами чи гормонотерапією, а також як метод лікування на І-му етапі розглянуто оперативне лікування.
Ретроспективно проаналізовано 115 випадків захворювання пацієнток на рак грудної залози І-ІІІ ст., люмінальних А- та В-типів, які отримали комплексне лікування у КНП “ПКОЦ ІФ ОР” протягом 2023 року. Вік пацієнток варіювався в діапазоні 28-87 років, у середньому становив 60±2-4 років. Кількість пацієнток з люмінальним типом А складала - 85, а з люмінальним В - 30. Неоадʼювантне хіміотерапевтичне лікування отримали 35 пацієнток, неоадʼювантну гормонотерапію - 15. Прооперовано на першому етапі - 65 пацієнток. На основі таких досліджень вивчалась відповідність отримання певного ступеня патоморфозу (І–IV ст.) до імуногістохімічного, морфологічного типу та схеми лікування.
Мета. Вивчити та оцінити ефективність неоад’ювантного хіміотерапевтичного лікування у пацієнток з гормонзалежними формами раку грудної залози.
Матеріали та методи. Ретроспективно проведено аналіз етапів лікування у 115 пацієнток на рак грудної залози І-ІІІ ст., люмінальних А- та В-типів, які отримали комплексне лікування у КНП «ПКОЦ ІФ ОР» протягом 2023 року.
Результати. Проаналізовано використання схем неоад’ювантного лікування, хіміотерапевтичного та гормонального відповідно до імуногістохімічних та морфологічних типів, стадій та ступенів диференціації пухлин.
Висновки. У результаті проведеного дослідження щодо отримання пацієнтками з гормонозалежним раком грудної залози передопераційного системного лікування ми змогли оцінити відповідність отриманих патоморфозів до отриманої схеми лікування. Відповідно ефективність неоад’ювантного системного впливу спостерігалась як при отриманні хіміотерапевтичних препаратів, так й антигормональних, що, у свою чергу, мають меншу токсичність, непереносимість та побічну дію препаратів, що вказує на доцільність більшого обговорення індивідуалізації системного лікування на доопераційному етапі.
ANALYSIS OF METACHRONOUS MALIGNANT DISEASES IN BREAST CANCER PATIENTS
Authors: Kostelei S. V. , Kysylytsia O. V. , Vytrykhovska I. V. , Drin I. T. , Hrytsyk R. A. , Dyakiv I. B.
Published: June 2024

Рак грудної залози (РГЗ) посідає перше місце серед усіх злоякісних новоутворень жіночого населення.
Міжнародне агентство ВООЗ із дослідження раку (IARC) прогнозує до 2050 року значне збільшення захворюваності на рак і подвоєння летальних випадків. 
У структурах злоякісних новоутворень полінеоплазії займають у середньому 2,47%, і їхня частка продовжує зростати. Серед жінок найбільш уразливою до первинно-множинних злоякісних пухлин є репродуктивна система. Найчастіше спостерігаємо поєднання гормонально-залежних утворень (раку грудної залози (РГЗ), тіла матки (РТМ) і яйників (РЯ)) із раком товстої кишки (РТК) та шлунка (РШ)). Вагомий вплив на це явище мають хвороби цивілізації.
Мета дослідження. Проаналізувати метахронні неоплазії в пацієнток на рак грудної залози.
Матеріали і методи. Ретроспективно досліджено 73 пацієнтки з метахронними полінеоплазіями, які лікувалися в КНП “ПКОЦ ІФ ОР” із 2019 по 2023.
Результати. У структурі пацієнток на первинно-множинний РГЗ переважали працездатні жінки (50-59 років) з метахронними РТМ, РЯ, РТК чи РШ (44%). Рак тіла матки й товстої кишки здебільшого діагностували через 10 років (33,33% і 52,17% відповідно), рак шлунка – упродовж року (40%), а рак яйника – за 5 років (50%). Згадані метахронні пухлини здебільшого виникали в пацієнток на первинно-діагностований РГЗ ІІА-ІІВ стадії. РТМ і РЯ найчастіше асоціюються з люмінальним В типом РГЗ (38,89% і 57,14% відповідно), а РТК – з люмінальним А (44,45%). РШ однаково пов’язаний з люмінальним В і Her2/neu-позитивним підтипами (по 50%).
Висновки. Необхідне надалі вивчення взаємозв’язку між раком грудної залози та метахронними раками тіла матки, яйника, товстої кишки й шлунка. Отримані знання варто спрямувати на покращення програм скринінгу та ранньої діагностики раку грудної залози й полінеоплазій. Беручи до уваги всі ключові фактори, варто спробувати розробити алгортм підрахунку ризику метахронних пухлин у пацієнток на первиннодіагностований рак грудної залози.