bluuebunny/crossref_metadata_2025 huggingface dataset:
Risk Analysis of Malpractice at Central General Hospital Friendship Jakarta
Authors: Baik Marpikir Manalu Marsada , Markoni Markoni
Published: May 2024

In the world of health services, many risks may be used as legal cases, ranging from the arrival of patients' data collection until patients leave the place of service. Europe and America have characteristics of different types of malpractice incidents, and in Asia, there are both developed, developing, and underdeveloped countries. This study aims to examine and analyze the prevention of malpractice risk and the mechanism of malpractice risk at Friendship Center General Hospital. The research methods used are empirical and conceptual juridical research methods. Researchers use literature studies as a tool for collecting research materials. The results of the study found that Permenkes 11 of 2017 states that Patient Safety aims to improve the Quality of Service in health Service Facilities through the application of Risk Management in all Aspects of Health Services, which means that it is expected that with the application of good Risk management, the risk for complaints that lead to malpractice reporting in any form can be suppressed in such a way. Although the application of standard operating procedures in hospitals, the risk of malpractice complaints is still possible due to many things from various angles that cannot be explained in the regulations or cannot be explained due to other things regarding the ability of doctors/service officers to convey information about problems or obstacles obtained at the hospital including facilities and other unwritten rules,  So even though it has been prepared in such a way, the risk still occurs.
Juridical Analysis of Brand Dispute Resolution in Indonesia
Authors: Dipo Selogiri Siana
Published: May 2024

A good product must have good quality in itself and requires a brand so that consumers can easily remember it. Brands attached to a product, goods, and services are likened to two sides of a coin: closely related and needy. A critical point in trademark protection is that a mark cannot be registered based on an application filed by an applicant in bad faith. A registered mark is valid and has been registered at the Director General of IPR and obtained a registration number. One of the exciting cases regarding the brand dispute was between Irawan Widjaja and Lancaster, which was resolved through mediation. Mediation is a negotiation involving a third party who has expertise regarding effective mediation procedures and can help in conflict situations to coordinate their activities to be more effective in the bargaining process. This type of research is juridical normative, an approach based on the primary legal material by examining theories, concepts, legal principles, and laws and regulations related to this research. The result of this study is that the legal step chosen by Irawan Widjaja, namely through mediation, is very wise and appropriate, considering that the goal is to resolve it as quickly as possible at a relatively minor cost.
Legal Force of Transfer of Home Ownership Loans (KPR) from Debtors to Third Parties without Approval from The Bank
Authors: Susilowardani Susilowardani
Published: May 2024

Ownership of a house is now a benchmark as a form of primary needs of an individual and is used as land to invest because it has a relatively high economic value. It will be tough for low-income people to own a house by buying it in cash. For some people, building a house must incur relatively high costs. Therefore, banks provide financing funds so that people can own houses. One form of financing from banks is Home Ownership Credit or KPR. However, implementing homeownership loans (KPR) has various problems, including transferring rights to the object of home ownership loans (KPR) or mortgage loan offers. So the problem arises: How is the legal force of transferring home ownership loans (KPR) from debtors to third parties without approval from the bank? This research uses research methods in the form of descriptive analysis. The act of credit oper underhand, whether it is a sale, transfer, or anything carried out by the debtor without permission or the knowledge of the creditor or bank, is included in the type of violation, and the agreement is also not binding on third parties or new debtors. If the debtor makes the transfer before repayment at the bank, then the agreement made by the debtor to a third party is null and void.
Application of Parlimentary Treshold to the Sustainability of Political Parties from a Human Rights Perspective
Authors: Yani Ahmad Yani
Published: May 2024

Law has close relevance to justice. Elections in Indonesia's democratic state are a process of peaceful transfer of power carried out periodically and per the principles outlined by the constitution. There are times when people want supervision of the government. However, there are also times when people get tired of their representatives who continue to behave because of seemingly unlimited power. One of the issues hotly discussed when approaching the 2019 election yesterday was raising the Parliamentary Threshold. Based on this description, a formula can be drawn: How does the Parliamentary threshold affect the existence and development of political parties? The research method used is Normative Legal Research. Parliamentary threshold is recognized as one of many ways to simplify political parties. However, PT must also be recognized as one of the most effective ways because it does not threaten the existence of any particular political party.
The Strategic Role of the TNI in Preventing the Development of Radicalism in Indonesia in the Perspective of Law 34 of 2004
Authors: Suharyanto Suharyanto , Sugianto Sugianto
Published: May 2024

In the Law of the Republic of Indonesia number 3 of 2002 concerning national defense, it is said that national defense is prepared early to face existing threats. The purpose of state defense is to maintain and protect state sovereignty, maintain the territorial integrity of the Republic of Indonesia, and maintain the safety of the entire nation from all forms of threats both from outside and from within the country. The threats in question are divided into 3: military, non-military, and hybrid. Meanwhile, according to the priority scale, threats are divided into 2: actual threats and potential threats. One of the actual threats that occur in Indonesia can be seen from the problems of terrorism and radicalism that still often occur in various regions and communities in   Indonesia. In the Law of the Republic of Indonesia number 34 of 2004, it is stated that the TNI in carrying out its primary duties is carried out through war military operations and military operations other than war, where in more detail in article 7 paragraph (2) point (b) states that one of the military operations other than war (OMSP) is to overcome acts of terrorism, which according to the Center for Studies The TNI strategy in its study on the role of the TNI  in preventing the development of radicalism, terrorism is deeply rooted in radicalism.
The Power of Scientific Evidence in the Evidence System for Forest and Land Cases
Authors: Kusmiharsono Didik , Sura Anabertha Sembiring Malemna
Published: May 2024

The development of evidence in cases of land and forest fires is regulated in Article 96 of Law Number 32 of 2009 concerning Environmental Protection and Management. In regulating the extent of evidence in environmental cases, the Supreme Court through Decree of the Chief Justice No.36/KMA/SK/II/2013 concerning the Implementation of Guidelines for Handling Environmental Cases. The research in this study is normative juridical legal research or library research. Meanwhile, the literature review uses various secondary data such as primary legal materials. The results of the study show that regulations on the use of scientific evidence (scientific evidence) as evidence in land and forest fire cases are contained in Laws, Ministerial Regulations and Supreme Court Decisions regarding the use of scientific evidence (scientific evidence) as evidence in land fire cases. The obstacle in using scientific evidence (scientific evidence) as evidence in land and forest fire incidents is that the causal relationship element is very difficult to prove so it requires scientific evidence.
Criminological Analysis of LGBT Acts Committed by Unscrupulous Soldiers
Authors: Saadi Anwar , Sugianto Sugianto , Usman Usman
Published: May 2024

Today, there is a phenomenon of deviation in the behavior of social life of the community known as Lesbian, Gay, Bisexual, and Transgender (LGBT). It is strongly felt that the pattern of life in the LGBT phenomenon is a deviation from the social norms, religion, and ideology of Pancasila. From the aspect of positive law, no law can be applied to punish perpetrators of LGBT acts. What comes to the surface is precisely the pros and cons of the perspective on LGBT acts, whether they are included in the issue of violations of the law, are part of human rights, or deviations of social behavior, or just deviations of sexual orientation. Pro-LGBT groups stated that there should be no discrimination against LGBT groups, whether men, women, transgender, opposite-sex lovers, or same-sex lovers, because it is considered a human right. For the contra group to have a criminological point of view that LGBT acts are violations of the law, not part of human rights aspects, LGBT is a violation of standard norms of life, contrary to morals and ethics, is a sin according to religion, and is a threat to the cultural and ideological values of a nation. LGBT acts also occur by TNI soldiers. Lawmakers must be able to formulate the rule of law in providing guarantees of certainty, justice, and benefit for the Indonesian people in overcoming LGBT developments that are a threat to the life of the Indonesian nation. LGBT perpetrators of TNI Soldiers must be given strict sanctions because these actions are contrary to the code of ethics of TNI Sapta Marga Soldiers and the Soldier's Oath.
Certainty of the Death Penalty in Terrorism Crimes from the Perspective of International Criminal Law
Authors: Satria Bintang Angga , Helvis Helvis
Published: May 2024

Terrorism is an extraordinary crime which is classified as a crime against humanity (Crime Against Humanity), and is a serious threat to the supervision of every country because terrorism is an international crime which poses a danger to security, world peace and is detrimental to the welfare of society. It needs to be eradicated systematically. planned and sustainable so that the human rights of many people can be protected and upheld. The aim of this research is to find out the certainty of the Death Penalty in Terrorism crimes from an International Criminal Law Perspective and to find out regarding Human Rights to the certainty of the Death Penalty in Terrorism Crimes from an International Criminal Law Perspective. Data collection in legal writing is library research (library research). The debate regarding the death penalty is also related to the right to life which in international legal instruments and in the 1945 Constitution is included in the category of rights that cannot be reduced under any circumstances (non-derogable rights). The practice of capital punishment in Indonesia is still considered class biased and discriminatory. because in both the Criminal Code and the ICCPR the death penalty is permitted for the most serious types of crimes, including the crime of terrorism.
Optimizing Healthcare Delivery: Analyzing the Relationship Between Inpatient Medical Record Return Time and Service Effectiveness at Ciremai Hospital
Authors: Syahr AlfiSyahr , Mustara Mustara
Published: May 2024

The medical record installation must maintain medical records correctly and appropriately, including the return of medical records. According to the Ministry of Health (2006), the standard for returning inpatient medical records is ≤ 2x24 hours after completion of treatment. Meanwhile, the standard of service effectiveness in the form of time for providing outpatient medical records according to Kepmenkes number 129 of 2008 is ≤ 10 minutes. The purpose of the study was to determine the relationship between inpatient medical record return time and service effectiveness. The research method used is quantitative with a cross-sectional design. The population is 220 medical records of post-inpatient patients who are controlled outpatients at Ciremai Hospital during January 2022. The total sample is 145 using the Slovin formula with the purposive sampling technique. Univariate analysis using frequency distribution and bivariate analysis using the Spearman rank correlation test are used because the data is not normally distributed. The results show that the average time to return inpatient medical records is 115,86 hours, the fastest time is 24 hours, and the longest time is 360 hours. The average service effectiveness in the form of outpatient medical record provision was 222,26 minutes; the fastest time was 3 minutes; and the longest time was 710 minutes. The Spearman rank correlation coefficient is 0,418 with a p-value of 0,000 ≤ 0,05. The conclusion is that there is a relationship with moderate correlation strength between inpatient medical record return time and service effectiveness, with a value of 0,418.
Nurse Therapeutic Communication Relationship with Parental Anxiety Levels which Preschoolers Undergo Hospitalization in the Lima Ranap Room Mitra Plumbon Hospital
Authors: Musyarofah Musyarofah , Fajrin Kurniawan Fakhri
Published: May 2024

Problems that generally affect the level of anxiety of parents whose preschoolers undergo hospitalization are divided into two objects, internal factors including: (1) Age factors owned by parents; (2) Sex differences of parents; and (3) Traumatic fears felt by parents. While from the external include: (1) The level of education of parents is quite low; and (2) Parents' knowledge of children's health is still low. One indicator in lowering the anxiety level of the patient's parents is therapeutic communication skills. In general, the purpose of this study was to determine the relationship between nurses' therapeutic communication with the level of parental anxiety due to hospitalization in preschool-aged children at Ranap Lima Mitra Plumbon Hospital. This study uses quantitative research with a cross-sectional approach  and uses correlation or correlational research methods. The population in this study was all parents of patients whose preschool-aged children underwent hospitalization in Ranap Room Five of Mitra Plumbon Hospital. The sampling technique uses accidental sampling method  based on chance. In terms of this sampling, researchers conducted a study for one month, where the sample obtained was 28 respondents.
Review of ICD-10 Differences Chapter 5 Mental and Behavioral Disorders with DSM-5
Authors: Budiyanti Nita , Dewi Rahmawati Fitria , Sofiyah Sofiyah
Published: May 2024

ICD-10 Chapter 5 "Mental and Behavioral Disorders" is used to record the diagnoses of all patients seen in psychiatric treatment. The DSM-5 is the standard classification of mental disorders used by mental health professionals in the United States. The differences in determining the diagnosis code in ICD-10 Chapter 5 Mental and Behavioral Disorders and DSM-5 can be influenced by the basic structure coding rules that follow in both classification systems. The purpose of this study was to determine the differences in the basic structure of ICD-10 Chapter 5 Mental and Behavioral Disorders with DSM-5. This research design uses literature review. The results of this study show that there are differences, among others, in the definition of the terms include  and  exclude in ICD-10 and DSM-5. Koder must improve the ability to understand definitions in the process of determining the codification of the two classification systems.
The Relationship of Sociodemographic Characteristics Toward the Level of Vitamin Swamedication Knowledge in the Community at A Pharmacy X, Cirebon Regency
Authors: Efriani Efriani , Nurlaela Nurlaela , Irawan Irawan , TA Putra , Hadi Hadi
Published: May 2024

Knowledge of a person's health determines behaviour when seeking treatment. Vitamin swamedication is a swamedication activity that uses vitamins needed by the body for normal metabolic processes and growth. This study was conducted to determine the relationship between sociodemographic characteristics and the level of knowledge of vitamin swamedication at Apotek X, Cirebon Regency. The method used is a cross sectional method with a sampling technique of consecutive sampling as many as 80 respondents. The data were analyzed by Spearman test using Statistical Product and Service Solutions (SPSS) version 25. The results showed the sociodemographic characteristics of the majority of respondents aged 26-45 years (44%), female gender (65%), education level SMA/SMK/MA (49%), and 55% of other occupations. Having sufficient knowledge level (63%) and having a relationship between sociodemographic characteristics in the form of education level with knowledge level of vitamin swamedication with p-value = 0.015 (p<0.05). The conclusion of the study is that there is a significant relationship between the level of education and the level of knowledge of vitamin swamedication.
Efficacy of Lavender Aromatherapy in Increasing Breast Milk Consumption Among Postpartum Mothers at Kertajati Health Centre
Authors: Ropiah Opi , Tonasih Tonasih , Mutya Sari Vianty
Published: May 2024

Breast milk production is a cumulative value based on what is seen and can be measured by the volume of milk a baby drinks for one day. The causes of decreased breast milk are consumption of drugs and hormonal disorders. To overcome the issue of decreased drain generation, lavender fragrance-based treatment can be done. The reason for this ponder was to decide the adequacy of giving lavender fragrance-based treatment to expand the sum of drain excretion in postpartum moms. This type of investigation is pre-experimental, with a number of pretest-posttest designs. Total sampling is a technique for sampling. The comes about appeared that the normal sum of breastfeeding time recently given fragrance-based treatment was 72.75. The minimum amount of breastfeeding in postpartum mothers is 60 cc and the maximum amount is 85 cc. After aromatherapy, the average amount of nursing in postpartum women is 100.25. Giving lavender aromatherapy is beneficial in raising milk production in postpartum moms, and it is anticipated that Kertajati Health Center in Majalengka Regency would be able to use this approach as a non-pharmacological treatment to improve milk production.
Mobilization of Stroke Patients to Prevent Decubitus: A Systematic Review
Authors: Farid Rivai Ahmad , Nur Imani Meli
Published: May 2024

Stroke is a disease or nerve disorder that occurs suddenly due to impaired blood flow to the brain. Stroke is known to cause various complications including the occurrence of decubitus wounds. Decubitus is one of the most frequent complications experienced by stroke patients. One of the therapies that can be given to prevent these complications is to take mobilization actions. The purpose of this literature review has been to analyze the provision of mobilization measures in stroke patients to prevent decubitus. The search method uses the Mendeley, PubMed, and Google Scholar databases between 2017 and 2021, with the keyword "Mobilization and Patient Stroke and Pressure Sores" obtained from 100 journals, from the Mendeley 82, PubMed 1 and Google Scholar 17 databases, then from these 100 journals a selection was made and 5 articles were obtained that can be reviewed according to the inclusion criteria. Results and Discussion of a review of literature review in 5 articles stated that mobilization measures can prevent decubitus in stroke patients. Mobilization can facilitate circulatory circulation, maintain muscle tone, and maintain and increase joint range of motion. Mobilization can be given to stroke patients with mobilization actions in the form of changes in the right tilt position, left tilt, and changes in tilt position 30 degrees. This position change can be done every 2 hours. The conclusions and recommendations of this literature review suggest that the administration of mobilizing measures is effective in preventing the occurrence of decubitus in stroke patients. For this reason, this research recommendation is that patients with bed rest be mobilized and given olive oil smears.
Factors Associated with the Incidence of Anemia in Toddlers at RS Dera As-Syifa Banjarharjo
Authors: Felawati Ela , Nurhasanah Nurhasanah , Ratnasari Eka
Published: May 2024

The incidence of anemia is a global problem that occurs in developed and developing countries that can have an impact on health, social and economic. Based on data from the World Health Organization (WHO) estimates that 42% of children under 5 years and 40% of pregnant women in the world suffer from anemia. The increased incidence of anemia of toddlers can be caused by the nutritional needs of toddlers more during the growth period. Toddlers who have anemia can have an impact on their immune system and intellectual abilities. The purpose of this study was to determine the factors associated with the incidence of anemia in toddlers at Dera As-Syifa Hospital Banjarharjo Brebes in 2023. This study design used analytical observational research with a cross sectional approach. The sampling technique in this study used a total sampling of 30 people. The results showed that based on the results of the spearman test, a p-value of 0.00 < 0.05 was obtained, which means that there is a relationship between birth weight, parents' economic status and maternal knowledge with the incidence of anemia in toddlers at Dera As-syifa Hospital Banjarharjo Brebes. The conclusion of this study is that there is a relationship between birth weight, parents' economic status and maternal knowledge with the incidence of anemia in toddlers at Dera As-syifa Hospital Banjarharjo.
The Effect of Oxytocin Massage on Breast Milk Production in Postpartum Mothers at Sidamulya Health Center Cirebon Regency
Authors: Khulaili Barkah , Mutya Sari Vianty , Aliah Nur , Difta R Siti
Published: May 2024

Exclusive breastfeeding affects the quality of the baby's health. But in practice, it is still relatively low. Data from the Puskesmas in 2022 achieved 55% exclusive breastfeeding and 48% achievement of exclusive breastfeeding in Sidamulya village. Low coverage of exclusive breast milk can be done by stimulating production. Oxytocin massage is one solution to overcome the smooth production of breast milk (ASI). The purpose of this study was to determine the effect of oxytocin massage to increase breast milk production in postpartum mothers at  Sidamulya Health Center, Astanajapura District, Cirebon Regency. Quasi-experimental research method with pretest and posttest approach without control group. The sample of this study was 20 people who were postpartum mothers for 7-9 days at  Puskesmas Sidamulya, Astanajapura District, Cirebon Regency in April – June 2023 with Total Sampling techniques. Data were analyzed using univariate analysis of frequency distribution and bivariate analysis of t-test. Univariate results of breast milk production in postpartum mothers before oxytocin massage on average day 1 = 40,625 ml, day 2 = 50,300 ml, day 3 = 57,725 ml, after oxytocin massage average day 1 = 48,025 ml, day 2 = 56,675 ml, day 3 = 63,375 ml. The paired simple t test results obtained p value = 0.000. There is an effect of oxytocin massage on milk production. It is hoped that the family can motivate the mother in the breastfeeding process by giving oxytocin massage so that the mother can exclusively breastfeed her.
The Effectiveness of Lavender Aromatherapy on Pain Scores for Post Sectio Caesarea in The Puskesmas Sukahaji Majalengka Regency
Authors: Agustina Risvianti Eka , Mutya Sari Vianty , Widayanti Wiwin , Rizki Nurfita Nisa
Published: May 2024

Sectio Caesarea (SC) deliveries have a higher risk because the surgery is performed by opening the abdominal wall and uterine wall or a trans-abdominal incision of the uterus. Patients with SC will feel pain. Therefore, pain management will be more effective when combined with non-pharmacological therapy. One of the non-pharmacological therapies that can be applied is aromatherapy. The purpose of this study was to determine the effectiveness of lavender aromatherapy on the pain score of post sc in the area of Puskesmas Sukahaji Kab Majalengka Tahun 2023. The design used is a quasi-experimental with one shoot only, the number of samples is 15 intervention groups and 15 control groups, the sampling technique uses purposive sampling. The results of data analysis obtained an average value in the intervention group of 2.60 and the control group of 7.33. The results of the Mann Whitney test. Research result obtained a value of p = 0.000 or p <0.05 meaning that lavender aromatherapy is effective against post SC maternal pain scores. Lavender aromatherapy is effective for post SC maternal pain scores in the Sukahaji Health Center area in 2023. It is hoped that it can be used as a complementary therapy in pain management so that it becomes a holistic and comprehensive treatment therapy
The Effect of Katuk Leaf Soup (Sauropus Androgynus) on the Amount of Breast Milk of Postpartum Mothers at PMB Ade Mila Marliana, Babakan Jawa, Majalengka in 2023
Authors: Annisa Zain Dhiya , Mutya Sari Vianty , Tonasih Tonasih
Published: May 2024

Breast milk is the best liquid for newborns until the age of 6 months, because the components of breast milk are easily digested and absorbed by the baby's body. There are many ways to increase breast milk, one of them is by consuming traditional medicinal plants, namely katuk leaf. The purpose of this research is to determine the effect of katuk leaf soup on the amount of breast milk for postpartum mothers at PMB Ade Mila Marliana, SST. This research used pre-experimental design with one-group pre-post test design. The population in this research was all postpartum mothers who gave birth at PMB Ade Mila Marliana, S.ST for the period April-May 2023 as many as 20 people. Sampling in this research using total sampling technique. Data analysis includes univariate analysis using frequency distribution and bivariate analysis using the Wilcoxon test. The results of the analysis using Wilcoxon obtained a p value of 0.000 (<0.05). The conclusion of this research is that there is an effect of katuk leaf (Sauropus Androgynus) on the amount of breast milk for postpartum mothers at PMB Ade Mila Marliana, SST Kelurahan Babakan Jawa, Kabupaten Majalengka. This research is expected to be an input for further researchers to develop research related to the effect of katuk leaf on the amount of breast milk for postpartum mothers.
The Effectiveness of the HYPO Method (Hypnobreastfeeding and Oxytocin Massage) with Breast Milk Expenditure in Postpartum Post-Sc Mothers at RSIA Cahaya Bunda Cirebon City in 2023
Authors: Fikriyyah Dinah , Mutya Sari Vianty , Aliah Nur
Published: May 2024

With all these factors, it helps mothers and their families, especially their husbands, to be able to do oxytocin massage and hypnosis so that they can release the hormones prolactin and oxytocin to trigger milk release. (Josefa, 2013). The importance of exclusive breastfeeding can be seen from the role of the world, namely in 2006 the World Health Organization (WHO) issued Child Growth Standards which were then applied throughout the world whose contents emphasized the importance of giving only breast milk to babies from birth to 6 months of age. (Prasetyono, 2009). Apart from that, the importance of breastfeeding was also seen in world events, namely the World Breastfeeding Week in August 2008, The World Alliance For Breast Feeding Action (WABA) chose the theme Mother Support: Going For the Gold. The meaning of the theme is a movement to invite everyone to increase support for mothers to provide their babies with gold standard food. This study uses comparative research. That is using a control group design research. In this study there were two groups, namely the control group without treatment and the intervention group with treatment, then the results were measured through observation before being processed in the SPSS test. In the control group without intervention, the results of the majority of breastfeeding were ≤ 20 ml as much as 95%. Meanwhile, in the intervention group with the treatment, there was a majority of > 20 ml of breast milk expenditure, as much as 90%. The average value of breastfeeding was 34.50 ml for the intervention group, 15 ml for the control group. There is an effectiveness between the HIPO method (Hypnobreastfeeding and Oxytocin Massage) and milk production in postpartum post SC mothers at RSIA Cahaya Bunda Cirebon with a significance value of 0.000 <0.05.
The Relationship of Sociodemographic Characteristics Toward the Level of Vitamin Swamedication Knowledge in the Community at A Pharmacy X, Cirebon Regency
Authors: L Efriani , S Nurlaela , A Irawan , TA Putra , I Hadi , S Marfuati
Published: May 2024

Knowledge of a person's health determines behavior when seeking treatment. Vitamin self-medication is a self-medication activity that uses vitamins needed by the body for normal metabolic processes and growth. This study was conducted to determine the relationship between sociodemographic characteristics and the level of knowledge of vitamin self-medication at Apotek X, Cirebon Regency. The method used is a cross sectional method with a sampling technique of consecutive sampling as many as 80 respondents. The data were analyzed by Spearman test using Statistical Product And Service Solutions (SPSS) version 25. The results showed the sociodemographic characteristics of the majority of respondents aged 26-45 years (44%), female gender (65%), education level SMA/SMK/MA ( 49%), and 55% of other occupations. Having sufficient knowledge level (63%) and having a relationship between sociodemographic characteristics in the form of education level with knowledge level of vitamin self-medication with pValue = 0.015 (p<0.05). The conclusion of the study is that there is a significant relationship between the level of education and the level of knowledge of vitamin self-medication
The Relationship of Maternal Knowledge about Breastfeeding with Exclusive Breastfeeding in Infants Aged 7-12 Months in the Working Area of Puskesmas Balida Dawuan District Majalengka in 2023
Authors: Sri Purwanti Endah , Mutya Sari Vianty , Tonasih Tonasih
Published: May 2024

Early and exclusive breastfeeding is very important for the survival of a baby, and to protect them from various diseases that they are susceptible to and which can be fatal. The government policy regarding exclusive breastfeeding is regulated in Law Number 36 of 2009 Article 128 paragraphs 2 and 3 which states that during breastfeeding, the family, local government and the community must fully support the mother by providing special time and facilities. The purpose of this study was to determine the relationship between mother's knowledge about breastfeeding and exclusive breastfeeding in the Working Area of ​​the UPTD Balida Health Center, Dawuan District, Majalengka Regency in 2023. This research method is a quantitative study with a descriptive correlation design with a cross sectional approach and probability sampling techniques. sampling with simple random sampling. Respondents in this study amounted to 66 respondents. the results of this study were that the majority of respondents gave exclusive breastfeeding 34 respondents (51.5%), most of the respondents had sufficient knowledge as many as 41 respondents (62.1%) and there was a relationship between mother's knowledge about exclusive breastfeeding with the results of the chi statistical test square with a p value of 0.000 (<0.005). The conclusion in this study is that there is a significant relationship between mother's knowledge about breastfeeding and exclusive breastfeeding.
Management of Warm Compresses in Typhoid Fever Children
Authors: Zaitun Zaitun , Yuliani S Ayu , Ameliya Feni
Published: May 2024

School-age children are easily targeted for various diseases, especially gastrointestinal diseases because school-age children have not paid much attention to their health, including the snacks they eat. Digestive diseases that most often infect school-age children due to poor schoolchildren's snacks include typhoid fever. Typhoid fever is a disease caused by Salmonella Thypi bacteria.  The priority of treatment in typhoid fever patients is hyperthermia management with the application of warm compresses that can help lower the body temperature of patients with typhoid fever.  Purpose: From this case study, it is to help reduce body temperature against hyperthermy in school-age children with a medical diagnosis of typhoid fever at Arjawinangun Hospital Cirebon.  Method: This scientific paper uses a descriptive qualitative design with the number of subjects as many as 2 respondents of school-age children with a medical diagnosis of typhoid fever who were given an intervention, namely a warm compress. Data collection techniques use interviews, observations and documentation studies. Conclusion: after the cooperative action, one experienced a temperature decrease of 1.1°C from 37.8°C to 36.7°C while patient 2 experienced a temperature decrease of 1.7°C from 38.3°C to 36.6°C. Suggestion: the patient's family can perform the very conflict act independently that has been taught by the nurse and in accordance with the standard operating instructions for warm compress procedures in the manual.
The Role of Check-in Counter Division in Passenger and Baggage Profiling Service at Sriwijaya Air Soekarno-Hatta International Airport
Authors: Almas Sugiarti Afifah
Published: May 2024

This study aims to determine the role of the check-in counter division in passenger and baggage profiling services at Sriwijaya Air Soekarno Hatta International Airport. In this study, the authors used descriptive research methods with a qualitative approach. The results of this study indicate that the role of the check-in counter division is very important in the smooth service process at the time of departure and in the service of profiling passengers and baggage, in the implementation of check-in services it is a procedure that must be carried out in every check-in service process. Therefore, the check-in counter division should pay attention to the quality of service that will be provided to each passenger in the implementation of passenger and baggage profiling services at check-in based on the dimension of service quality initiated by Kotler, namely Tangible dimensions, Reability, Responsiveness, Assurance, and Emphaty and its indicators. It can be concluded that there is a dimension of service quality Tangible, Reability, Responsiveness, Assurance, and Emphaty in the implementation of check-in and profiling services in the check-in counter division of Sriwiijaya Air.
The Role of BUMDes in Overcoming Over Tourism in Bejiharjo Tourism Village Karangmojo District Gunung Kidul Regency
Authors: Khairune Nisa An Nuur
Published: May 2024

The topography of the Bejiharjo tourist village in the form of rice fields, rivers, caves is very supportive of various natural tourism activities. Cave tubing Goa Pindul is famous for its unique natural beauty, one of which is karst stalactites and stalagmites attracting the attention of tourists so that overtourism occurs. The research was conducted with the aim of finding out how the Bumdes Institution can overcome the problem of overtourism. The research method used is descriptive research, data obtained by interviews with stakeholders. The results show that the Bumdes Institution plays a role in overcoming overtourism by providing alternative diversions of tourists who come to Pindul Cave to other tourist destinations in the Bejiharjo tourist village. The community worked hard hand in hand in tourism awareness groups resulting in the success of villagers in the Bumdes Institution to manage and promote the potential of the Bejiharjo tourist village so that it became one of the leading tourist villages in Gunung Kidul Regency, Special Region of Yogyakarta and in 2012 was named the best tourist village by the Ministry of Tourism and Creative Economy.
Investigation of Anthelmintic Property of Cow Urine Distillate on Ascaris and Trichuris eggs Isolated from Soil
Authors: Nisha Mehru , Yusri Ruziana , Chyang Pang Jyh
Published: May 2024

Background: Helminth infection occurs due to contact with contaminated soils and poor hygiene practices. Even though there is immense progression in human medicine, infections that occur due to bacteria, fungi, viruses, and parasites persist as a crucial threat to public health. Over the years, many studies indicated cow urine has antimicrobial activity. Hence, this study looks into anthelminthic property of cow urine in Ascaris spp., and Trichuris spp., eggs. Methods: The soil sample was collected at the riverside, near the toilet area and at the pond area at an aborigine village in Malaysia. Next, floatation technique was used to isolate the helminth eggs and it was identified using a light microscope. The cow urine was prepared as raw cow urine (RCU), evaporated raw cow urine diluted with distilled water (ERCUD), evaporation raw cow urine diluted with saline (ERCUS) and evaporated filtered cow urine diluted with saline (EFCUS).Results: From the soil samples, mainly two types of helminths were found which were Ascaris lumbricoides and Trichuris trichiura. Evaporated cow urine diluted with saline showed the most prominent result in the destruction of helminth eggs.Conclusion: Evaporated cow urine possesses biochemical agents that can be used in the future as anthelmintic agents whereby further studies can be made to explore more possibilities to use cow urine as a potential anthelmintic agent.Keywords: Cow urine; Helminth eggs; Anthelmintic
Elucidating Severity of Waves of COVID-19 in Pakistan
Authors: Zia Rabia , Mumtaz Zilwa , Rahid Zubia , Ali Ashaq , Yousaf Muhammad Zubair
Published: May 2024

Background: COVID-19 has radically changed the globe. This virus has a powerful impact on almost every country in the world. The most significant hurdle arises for the overall capacity of a disease control when the number of cases peaks during each wave of the pandemic. There are various waves that have occurred in the preceding period, each of them is characterized by a distinct variant of the virus. For a developing country like Pakistan COVID-19 ruins every sector of the country. There is a proper need for care and protection from this virus as guided by the World Health Organization (WHO). The spread rate is different in every country based on various factors. Two or more factors are required to trigger a high infection rate.Methods: The data sourced from the National Command and Operations Center (NCOC) was focused on analyzing the data from the four waves of COVID-19 in Pakistan encompassing reported cases, death and testing capacity. Utilizing the SPSS software, a comprehensive examination of these factors was performed.Results: The data of four waves has been analyzed including reported cases, no. of death, and testing capacity of the country. The data analysis reveals there is a strong correlation between these factors. By the interpretation of the data, it reveals upcoming waves are more dangerous than earlier due to new mutations.Conclusion: The virus is evolving to become more contagious and infectious in each consecutive wave. Vaccination should be considered compulsory for everyone to win the battle against the virus. Data analysis revealed a correlation between the number of cases and passage of time, showing that the new waves will emerge earlier and have a significant impact on the country.Keywords: COVID-19; Pakistan; Waves of COVID-19; Vaccination
Severity Assessment and IL-5 Evaluation after Immunotherapy in Atopic Dermatitis Mice
Authors: Anggraeni Sylvia , Triesayuningtyas Dinar Chieko , Luthfidyaningrum Hamidah , Hendaria Made Putri , Widia Yuri , Endaryanto Anang , Prakoeswa Cita Rosita Sigit
Published: May 2024

Background: The effectiveness of immunotherapy in atopic dermatitis (AD) has been debated for many years. Immunotherapy suppresses Th2 cytokines, such as IL-5, which play a crucial role in the pathogenesis of AD. This study assessed the effect of immunotherapy on severity and IL-5 expression in AD mice.Methods: Male BALB/c mice were separated into three groups. The mice were sensitized with Dermatophagoides pteronyssinus allergen for seven days, except the mice in control group. The house dust mite (HDM) immunotherapy was injected subcutaneously every 3 days for 1.5 months with increasing doses (0.1, 1, 10, 100 μg in 100 μL PBS) every 4 injections. The mice in AD model and control group received placebo injections. Following immunotherapy, the mice were exposed to HDM allergen patch two times with 2 weeks interval in between. The mice were evaluated for severity score as the clinical marker and IL-5 expression with semiquantitative method as the histological marker.Results: The evaluation of severity score from two independent researchers showed a substantial agreement (Cohen’s kappa 0.613, p <0.001). The severity score of the immunotherapy group was significantly lower than the AD model group, while both immunotherapy and AD model group had significantly higher score than control group. IL-5 expression in the immunotherapy group was lower than the AD model group and slightly higher than control group. The mean difference between groups was not significant.Conclusion: The severity of skin lesion and IL-5 expression in AD mice receiving immunotherapy were lower than AD model group.Keywords: Atopic dermatitis; BALB/c mice; House dust mites; IL-5, Skin severity score; Tropical disease
Protective immune response of recombinant Fiber-2 protein as subunit vaccine against Fowl-adenovirus-4 infection in Pakistan
Authors: Ather Faiza , Zia Muhammad Ashir , Shah Muhammad Salahuddin , Habib Mudasser
Published: May 2024

Background: Hydropericardium Syndrome (HPS) has emerged as a major viral disease of poultry industry causing huge economic losses in the recent past years. Its etiological agent, Fowl adenovirus-4 (FAdV-4) has been reported in the various countries including Pakistan. Various strategies including inactivated vaccines, are being devised to control the disease since its appearance. Subunit vaccines based on viral structural proteins have demonstrated more promising protection against FAdV-4 infection than commercial inactivated vaccines. Among different viral structural proteins, Fiber protein (mainly Fiber-2) has been as a suitable candidate for developing the recombinant subunit vaccine against HPS.Methods: Considering the importance of the Fiber-2 gene, the pET28a expression vector was utilized to clone its open reading frame, which was subsequently expressed as an oligo-histidine tagged fusion protein in BL21 cells of Escherichia coli via the IPTG induction method. The expressed recombinant fiber-2 protein was purified using nickel (Ni2+) affinity chromatography and used as a subunit vaccine in broiler birds following challenge with pathogenic FAdV-4 isolate. The immunological response was evaluated using ELISA.Results: The gene for the Fiber-2 protein was effectively cloned and expressed as a soluble 60 kDa protein, as detected by SDS-PAGE and western blot analysis. The protective efficacy of subunit vaccine was assessed by ELISA which showed the highest protection (80%) against the virus challenge than that of commercial inactivated vaccine (70%).Conclusion: The recombinant fiber-2 protein was determined to be a good option for a recombinant subunit vaccination to control HPS.Keywords: Poultry; Fowl-adenovirus-4; Subunit vaccine
Gene Expression Profiling to Predict Prognostic Biomarkers for Relapse in Multiple Myeloma
Authors: Elahi Sana , Fazal Sahar
Published: May 2024

Background: Multiple myeloma (MM), an incurable malignancy of plasma cells (PCs), is the second most common hematological cancer caused primarily by structural variations (chromosomal aberrations and somatic mutations). The majority of the patients acquired resistance against standard therapeutic approaches for MM and experienced relapse despite the continuous advances in MM therapies.Methods: We performed Differential Gene Expression (DGE), literature mining and SNV analysis of Next Generation Sequencing (NGS) data of Newly Diagnosed MM (NDMM) and Relapsed/Refractory MM (RRMM). The selected Differentially Expressed Genes (DEGs) were subjected to functional enrichment and pathway analysis. Immune cells infiltration analysis was also performed to estimate immune cells variations in the Tumor Microenvironment (TME) of RRMM. Result: CSF1R, VCAN, NRP1, COL22A1, BPI, BIRC5, MNX1, FAT1, ERG, TCL1A, AFF3 were selected after DGE, literature mining and SNV analysis. The functional enrichment of these DEGs showed significant enrichment for positive regulation of cell population proliferation, serene/threonine kinase activity, endothelial cell proliferation, cytokine binding, G protein activity and GDP binding, whereas KEGG pathway analysis revealed vital role of PI3K-Akt signaling pathway along with various cancer pathways. The immune cells infiltration analysis revealed the higher count of neutrophils and  lesser level of T cells (CD8+) in TME of RRMM. Conclusion: Our study suggests that neutrophils play an important role in modulation of TME in RRMM. The selected DEGs have previously been identified in progression, drug resistance and relapse of various cancers. The role of these biomarkers in RRMM has not been explored yet. Therefore, neutrophils, selected DEGs and PI3K-Akt signaling pathway are potential targets to investigate in RRMM.Keywords: Multiple Myeloma; Relapse; Differential Expression; Immune Cell Infiltration; Literature Mining
In-vitro study on antioxidant status of Zinc NPs and crude extract of Ayurvedic herbal formulation
Authors: Alsadooni Jaafar Faez Kadhim , Khudhair Sura Razzaq
Published: May 2024

Background: To create and evaluate cutting-edge therapeutic composition on biosynthesized nanoparticles exhibiting varied biological activity, nanotechnology is a novel and forward-thinking method. Increased antioxidant activity decreased toxicity to free radicals as well as cancer cells, and other benefits are achieved carefully by regulating the form and nanoparticle dimensions.Methods: Nanostructures biosynthesized utilizing Liv-Pro-08 AHF showed a strong antioxidant effect. The creation of novel and more efficient antioxidants may benefit from the usage of nanoparticles. It is noteworthy that the resulting nanoparticles exhibit more biological processes than the extract. This research aims to calculate if there are any noticeable differences in the behaviour of leaf extracts and the many nanomaterials obtained from the aqueous-based separation of Liv-Pro-08 Ayurveda herbal-based formulations.Results: Several in-vitro free radical scavenging experiments were used to determine whether or not Liv-pro-08 nanoparticles possessed any antioxidant properties. Zinc nanoparticles generated from Liv-pro-08 ayurvedic formulation demonstrated dose-dependent suppression of DPPH, as well as concentration-dependent lowering power potential, indicating that the nanomaterials contain free radical scavenging capability to produce the antioxidant effect.Conclusion: Nanoparticles might be useful for the development of newer and more potent antioxidants. It is worth mentioning that the resultant nanoparticles possess an elevated biological activity in comparison to the extract. The data represented in our study contribute to a novel and unexplored area of nano materials as alternative medicine.Keywords: Antioxidants; Biosynthesis; Leaf extract; Liv-pro-08; Zinc