bluuebunny/crossref_metadata_2025 huggingface dataset:
The unstudied effects of wording and answer formats in the analysis of impartiality in public service provision
Authors: Martín Juan Carlos , Moreira Pedro , Román Concepción
Published: July 2023

Impartiality in public services provision is an important dimension that explains the quality of government (QoG). The analysis of impartiality has boomed in recent years at different territorial levels, like countries or regions. The impartiality measures depend on several attributes that are aggregated using different methods. However, little attention has been given to the effects of negative wording attributes and the number of format answers, despite the efforts made by previous studies to build robust composite impartiality indices. This study corrects this existing gap partly using one of the most extensive surveys (the European Quality of Government Index 2021) that include attributes related to impartiality (six attributes and 129,991 citizens). The method will be based on a fuzzy clustering approach, the extended Apostle model and an ordinary binary probit model. The results show that the type of wording and the number of answer options affect impartiality. The analysis of the main differences observed is affected by some insightful covariates such as country, gender, being native, town size, occupation, and the perception of the economic situation.
Small molecule antagonists of PTPmu identified by artificial intelligence-based computational screening block glioma cell migration and growth
Authors: Molyneaux Kathleen , Laggner Christian , Vincent Jason , Brady-Kalnay Susann
Published: July 2023

PTPmu (PTPμ) is a member of the receptor protein tyrosine phosphatase IIb family that participates in both homophilic cell-cell adhesion and signaling. PTPmu is proteolytically downregulated in glioblastoma generating extracellular and intracellular fragments that have oncogenic activity. The intracellular fragments, in particular, are known to accumulate in the cytoplasm and nucleus where they interact with inappropriate binding partners/substrates generating signals required for glioma cell migration and growth. Thus, interfering with these fragments is an attractive therapeutic strategy. To develop agents that target these fragments, we used the AI-based AtomNetⓇ model, a drug design and discovery tool, to virtually screen molecular libraries for compounds able to target a binding pocket bordered by the wedge domain, a known regulatory motif located within the juxtamembrane portion of the protein. Seventy-four high-scoring and chemically diverse virtual hits were then screened in multiple cell-based assays for effects on glioma cell motility (scratch assays) and growth in 3D culture (sphere assays), and PTPmu-dependent adhesion (Sf9 aggregation). We identified three inhibitors (247678835, 247682206, 247678791) that affected the motility of multiple glioma cell lines (LN229, U87MG, and Gli36delta5), the growth of LN229 and Gli36 spheres, and PTPmu-dependent Sf9 aggregation. Compound 247678791 was further shown to suppress PTPmu enzymatic activity in an in vitro phosphatase assay, and 247678835 was able to inhibit the growth of human glioma tumors in mice. We propose that these three compounds are PTPmu-targeting agents with therapeutic potential for treating glioblastoma.
Overexpression of TCP9-like gene enhances salt tolerance in transgenic soybean
Authors: Zhang Zhuo , Zhao Yuanling , Chen Yifan , Li Yueming , Pan Lijun , Wang Siyu , Wang Piwu , Fan Sujie
Published: July 2023

TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR (TCP) transcription factors are a plant-specific family and play roles in plant growth, development, and responses to biotic and abiotic stresses. However, little is known about the functions of the TCP transcription factors in the soybean cultivars with tolerance to salt stress. In this study, TCP9-like, a TCP transcription factor, was identified in the soybean cultivars exposed to salt stress. The expression of TCP9-like gene in the roots of salt-tolerant soybean cultivars was higher than that in salt-sensitive cultivars treated with NaCl. The overexpression of TCP9-like enhanced the salt tolerance of the salt-sensitive soybean cultivar ‘DN50’. In T2 generation, the plants with TCP9-like overexpression had significantly lower Na+ accumulation and higher K+ accumulation than the WT plants exposed to 200 or 250 mmol/L NaCl. The K+/Na+ ratio in the plants overexpressing TCP9-like was significantly higher than that in WT plants treated with 200 mmol/L NaCl. Meanwhile, the overexpression of TCP9-like up-regulated the expression levels of GmNHX1, GmNHX3, GmSOS1, GmSOS2-like, and GmHKT1, which were involved in the K+/Na+ homeostasis pathway. The findings indicated that TCP9-like mediated the regulation of both Na+ and K+ accumulation to improve the tolerance of soybean to salt stress.
Study protocol for FUTURES: Testing a web-based reproductive health education program for adolescent and young adult males with sickle cell disease
Authors: Colton Zachary A. , Stanek Charis J. , Liles Sophia M. , Baker Christian , Barnard-Kirk Toyetta , Chan Peter , McCorkle Ben , Quinn Gwendolyn P. , Shen Yvette , Theroux Charleen I. , Creary Susan E. , Nahata Leena
Published: July 2023

Individuals with sickle cell disease are increasingly surviving into adulthood, many of whom have interest in future biological parenthood. Reproductive health knowledge is low among adolescent and young adult males and their caregivers. Their understanding of these topics is needed to optimize their reproductive health outcomes. As such, through collaboration with a community advisory board (adolescents and young adults with sickle cell disease and mothers of adolescent and young adult males with sickle cell disease) and digital design team, we developed a web-based sickle cell disease-focused reproductive health program entitled FUTURES to address these knowledge gaps. For phase I of this two phase feasibility and acceptability study, adolescent and young adult males and their caregivers will complete a pre- and post-program reproductive health knowledge and attitudes questionnaire to assess change in knowledge. In phase II, after learning about fertility testing as part of the FUTURES curriculum, adolescent and young adult male participants are given the option to pursue testing. The two-phase study aims to: 1) develop and test the feasibility, acceptability, and efficacy of a reproductive health web-based educational program at increasing reproductive health knowledge in male adolescent and young adult males with sickle cell disease and their caregivers, and 2) assess feasibility of fertility testing. The long-term goal is to improve reproductive and psychosocial outcomes among adolescent and young adult males with sickle cell disease.
Special Issue: ‘Podcasting and Gender’
Authors: Trier-Bieniek Adrienne , Loviglio Jason , Lindgren Mia
Published: July 2023

This Special Issue, guest-edited by Adrienne Trier-Bieniek, Ph.D., brings together exciting new work on the growing number of podcasts focused on deconstructing gender inequality, particularly as an intersectional issue. The seven articles gathered here provide a broad and methodologically diverse perspective on some of the most exciting podcasts in this genre. Two book reviews on major books released last year conclude the issue.
‘Lean into the YIKES’: Caring intimate counterpublics and climate justice podcasting
Authors: Driver Susan
Published: July 2023

This article explores the ways an intersectional feminist climate justice podcast YIKES offers possibilities for intimate counterpublics and forms of engagement that centre on caring and activist connections. Bringing together theories of intimacy, care and counterpublics together to examine the specific ways YIKES fosters affective attachment and political interest in ways that allow for open-ended and non-linear forms of communication. This article offers a close reading of an episode that explores the caring dynamics of friendship as an intimate space through which difficult topics related to climate justice, power and inclusion are opened up for discussion and sharing. I argue the podcast enacts an ethos of interpersonal care while elaborating complex conditions for social and political intimacy within broader networked publics.
Efeito do tempo de cura na resistência e deformabilidade de um solo argiloso ligado com cimento
Authors: Santana Teresa , Dias João , Lamas Pedro
Published: July 2023

Este trabalho apresenta os resultados laboratoriais de um solo argiloso ligado com cimento, utilizando um cimento Portland, CEM IV/A 32,5 R, adicionado nas percentagens de 8 % e 12 % em relação à massa seca do solo. Foram realizados ensaios de compressão não confinada, em provetes compactados num molde Proctor com um teor em água ótimo (owc), para diferentes tempos de cura até 90 dias. Os resultados mostram que o uso de cimento permite um aumento na resistência à compressão de 30% até 7 dias de cura e apenas um aumento de 6% dos 7 aos 90 dias de cura, para os dois teores em cimento estudados. São propostas correlações entre a resistência à compressão não confinada, Rc e a percentagem de cimento e o tempo de cura, bem como para o módulo de deformabilidade secante, E30, permitindo prever, a longo prazo, o comportamento dessas misturas, conhecendo as propriedades de compactação e resistência do solo utilizado.
„Az etikus üzleti gyakorlat és a tisztességes, egyenlő versenyfeltételek egyetemes értékek”
Authors: Szabó Dorottya , Trautmann László , Lightfoot Jeffrey
Published: July 2023

A Világpolitika és közgazdaságtan interjút készített Jeff Lightfoottal, a CIPE, Center for International Private Enterprises európai programigazgatójával az etika szerepéről az üzleti életben és az ennek erősítésére szolgáló számos eszközről. Az szervezet eredményei több mint 1100 olyan etikai, megfelelőségi és jogi szakember véleményére épülnek, akik többségében legalább 1000 alkalmazottal rendelkező szervezeteknél dolgoznak. A válaszadók 60 százaléka Észak-Amerika területén kívül dolgozott, közülük 12 százalék az Egyesült Királyságból, 16 százalék Németországból és 20 százalék Franciaországból származik.
„Iránymutatás kell az önálló szabályalkotó gondolkodáshoz” : Interjú dr. Balog Ádámmal, a BKIK alelnökével
Authors: Szabó Dorottya , Trautmann László , Balog Ádám
Published: July 2023

A Világpolitika és közgazdaságtan interjút kért dr. Balog Ádámtól a compliance tudatosság szerepéről a kis- és középvállalatok körében, és arról, hogy miért fontos a szabályalkotás akár a vállalat belső működése, akár a vállalatok közötti együttműködés szempontjából, illetve, hogy mit tehet a kamarai rendszer a tudatosság növelése érdekében.
Együttműködés a BKIK, a BME és a Corvinus között kompetensebb startup csapatokért
Authors: Piricz Mihály
Published: July 2023

Az idei félévben egy különös, de mindenképpen előremutató együttműködés jött létre a Budapesti Kereskedelmi és Iparkamara által támogatott BKIK Akadémia, a Budapesti Műszaki Egyetem és a Budapesti Corvinus Egyetem között. A BME diákjai előálltak startup ötletekkel, (adott esetben a megvalósítást is elkezdték), ezekhez az ötletekhez pedig csatlakoztak a Corvinus gazdálkodási és menedzsment szakos, kisvállalkozás specializációjú hallgatók, hogy üzleti tervet írjanak hozzájuk.
Információ és kapitalizmus : Recenzió az „Az információs nexus” című könyvről
Authors: Csontos Tamás
Published: July 2023

Recenzió az „Az információs nexus” című könyvről Marks, S. G. (2016). The information nexus: global capitalism from the Renaissance to the present. Cambridge University Press.
Factors influencing the severity of COVID-19 course for patients with diabetes mellitus in tashkent: a retrospective cohort study
Authors: Alieva A. V. , Djalilov A. A. , Khaydarova F. A. , Alimov A. V. , Khalilova D. Z. , Talenova V. A. , Alimova N. U. , Aripova M. D. , Sadikova A. S.
Published: July 2023

BACKGROUND: Since the very first outbreak, scientists have been trying to determine the most critical pathogenetic mechanisms for the development of COVID-19 and related complications, analyze individual subpopulations of patients with chronic diseases and develop optimal tactics to combat not only the infection itself but also its acute and chronic complications.

AIM: to assess the COVID-19 course among patients with Type 1 and Type 2 DM.

MATERIALS AND METHODS: A retrospective cohort study of Tashkent inhabitants, who had COVID-19 from April to D ecember 2020, was performed. The data were obtained from the single electronic database of registered cases of COVID-19. All data were analyzed using a logistic regression in STATA 17.0 software. Further, the matched case-control study was performed for patients with type 2 DM and no DM based on age, gender, and BMI.

RESULTS: Of the 5023 analyzed subjects, 72.63% had no diabetes mellitus (DM), 4.24% had type 1 DM, 15.19% had type 2 DM, and 7.94% was diagnosed with DM during the COVID-19 infection. DM, overweight, and obesity were associated with severe COVID-19; the most significant risk of a severe course was found in persons with type 2 DM. The risk of a lethal outcome and the need for prescription of glucocorticoids did not show a significant association with diabetes in Tashkent. The clinical features of COVID-19 were more common in patients with type 2 DM, especially for shortness of breath, chest pain, and arrhythmia. The persons receiving SU have complained of dyspnea significantly more often than matched patients without DM. Metformin and DPP4i were the groups of drugs that were not associated with significantly increased risk of hospitalization of patients because of COVID-19. The matched case-control study did not reveal statistically significant differences in the disease course severity, need for hospitalization and glucocorticoids, and death depending on the glucose-lowering therapy preceding the onset of COVID-19.

CONCLUSION: Diabetes, age and overweight/obesity were associated with severe course of COVID-19 in Tashkent. There was no statistical difference in COVID-19 severity depending on initial glucose-lowering therapy.
Kosmischer Müll
Authors: Erdmann Dominik
Published: July 2023

Dominik Erdmann widmet sich in diesem Beitrag der Frage, inwiefern das Wegwerfen von Geschriebenem eine Voraussetzung für Alexander von Humboldts Bücher über die Natur darstellt und in welchem Zusammenhang es als Schreibpraxis betrachtet mit der epistemologie seiner Netzwerk- und Weltwissenschaft steht.
Eugenische Publikations-Szene
Authors: Basten Laura
Published: July 2023

Laura Basten untersucht in diesem Beitrag die Bedeutung von (Selbst-)Verlagen für die Herausbildung und Verfestigung eugenischer Argumente zu Beginn des 20. Jahrhunderts in Deutschland. Am Beispiel des Chemienobelpreisträgers Wilhelm Ostwald (1853-1932) wird gezeigt, dass dieser nicht nur als Verleger und Herausgeber auftrat, um Vorschläge zur Verzeichnung, Normierung und Sortierung von Archiven, Bibliotheken, der Wissenschaft u.a. machen zu können. Vielmehr lassen sich strukturelle Ähnlichkeiten zwischen materieller Ausstattung und sozialdarwinistischen Inhalten herausarbeiten. Die von Ostwald verantworteten Zeitschriften und Bücher werden daher sowohl als Diskursräume als auch als Artefakte betrachtet - und nicht zuletzt als »Ressourcen« des Widerstands.
»Papierbedarf: 0,3 Tonnen«
Authors: Kirsten Marlene
Published: July 2023

Marlene Kirsten widmet sich in diesem Beitrag einem bislang unbeachteten Aspekt der DDR-Literatur. Anlass für Überlegungen zum nachhaltigen Handeln der Verlagsindustrie bilden zwei aufwändig gestaltete Lyrikanthologien, »Bekanntschaft mit uns selbst« (1961) und »Sonnenpferde und Astronauten« (1964). Auf Basis von Archivmaterial wird untersucht, welche Überlegungen das Handeln des Mitteldeutschen Verlags leiteten. Der Blick auf die Verlagspraxis der DDR ermöglicht es, Nachhaltigkeit abseits ihrer gemeinhin üblichen ökologischen Bedeutung zu betrachten und in theoretischer Hinsicht um materialökonomische und kulturpolitische Aspekte zu erweitern.
Psychologie als eine Grundlage der Hochschuldidaktik
Authors: Mörth Martina , Paridon Hiltraut , Enders Natalie , Ulrich Immanuel
Published: July 2023

Mörth, Paridon, Enders & Ulrich stellen exemplarisch dar, bei welchen hochschuldidaktischen Fragestellungen psychologische Erkenntnisse hilfreich sein können. Sie erläutern, was die wissenschaftliche Psychologie im Gegensatz zur Alltagspsychologie ausmacht und welchen Beitrag sie für die Hochschuldidaktik liefern kann. In vier Tabellen stellen sie die psychologischen Grundlagen des Lernens, der Persönlichkeitsentwicklung, des sozialen Miteinanders, die psychologischen Grundlagen des Lehrens sowie psychologische Bezüge zur hochschuldidaktischen Lehrkompetenzentwicklung und zur hochschuldidaktischen Organisationsentwicklung dar. Durch die Berücksichtigung der fundierten psychologischen Erkenntnisse und Diskurse verwissenschaftlicht sich die Hochschuldidaktik und kann eine evidenz-informiertes Lehr- und Lerngestaltung fördern. Lehrende können die wissenschaftlichen Erkenntnisse in ihre didaktischen Entscheidungen einfließen lassen.
On Some Absent Presences of Nuclear Extractivism: Retrofuturist Aesthetics and Fallout 4
Authors: Crane Kylie
Published: July 2023

In this contribution, Kylie Crane examines nuclear entanglements with a view to extractivism and externalisations of risk. Using the computer game Fallout 4 (Bethesda), she considers the way temporal omissions and retrofuturist aesthetics interact to evoke a gameworld marked by nuclear detonations. These detonations and the concommitant risks are, crucially, rendered elsewhere or 'elsewhen', which becomes particularly evident in the ways revisionary politics of historical contexts are folded into the ludic present.
"This Is Our Barn": Agrarian Sentimentality and the Fracking Formula in Promised Land
Authors: Germanaz Axelle , Marak Sarah
Published: July 2023

Axelle Germanaz and Sarah Marak examine the ways in which Gus Van Sant's 2012 movie Promised Land portrays the controversial debate surrounding hydraulic fracturing (i.e. fracking) in the United States. The authors argue that the film exemplifies what they call the »fracking formula,« which describes a culturally specific set of key themes, settings, and stock characters typically found in narratives about fracking, and relies on a narrative of »agrarian sentimentality« that romanticizes small-town rural life not only as the last stronghold of original US American values but also as the ultimate bastion against extractivism.
»Klimamigration«
Authors: Schraven Benjamin
Published: July 2023

Die Folgen des Klimawandels sind nicht mehr zu übersehen - und in Europa hält sich hartnäckig die Angst, dass seine verheerenden Auswirkungen in naher Zukunft eine gigantische Flüchtlingswelle anstoßen werden. Aber was wissen wir wirklich über die Auswirkungen der Erderwärmung auf Flucht und Migration? Benjamin Schraven erläutert, warum europäische Befürchtungen vor Millionen von »Klimaflüchtlingen« aus Teilen Afrikas oder Asiens viel mehr einer verzerrten Wahrnehmung als einer tatsächlichen Problemanalyse entspringen. Er stellt jedoch klar: Die Klimamigration ist ein virulentes Thema, mit dem Politik, Gesellschaft und Medien einen anderen Umgang finden müssen.
Guantánamo bezeugen
Authors: Köthe Sebastian
Published: July 2023

Mindestens 780 Menschen wurden seit dem 11. Januar 2002 in das extraterritoriale Gefangenenlager Guantánamo Bay entführt. Sebastian Köthe erzählt die Geschichte von Widerstand und Folter im Lager anhand der Zeugnisse der Gefangenen. Er analysiert Knotenpunkte wie Isolation und Beziehungsstiftung, Hungerstreik und Zwangsernährung, Gefangenschaft und Suizid. Dies führt zur Diagnose einer Folterkultur, an der Politik und Künste teilhaben. Folter wird einerseits ausgestellt, um ganze Bevölkerungsgruppen zu bedrohen und die Exekutive zu ermächtigen, und andererseits verheimlicht und verharmlost, um Täter*innen zu schützen. Am Beispiel von Spiel- und Dokumentarfilmen sucht dieser Band nach den Konturen einer Antifolterkultur, die auf die Zeugnisse der Überlebenden antworten könnte.
4. Postclassical Marble: Reclaiming Flux in the Reception of Marble in Contemporary Art
Authors: Pourcq Maarten de
Published: July 2023

In this chapter, Maarten De Pourcq takes marble as his starting point for his inquiry into the reception of Greco-Roman antiquity. Concentrating on Kara Walker's installation Fons Americanus (2019), his chapter takes a materials-based postclassical stance, first, on the way in which white marble became a central element of the art-historical paradigm of classicism and, second, on the role played by white marble in contemporary artworks that question classicist paradigms by calling attention to their materials and the contingency of their presence, monumentality, and social use.
9. Harnessing the Sun in Tech-on-Climate Discourse
Authors: Riemens Rianne
Published: July 2023

In this chapter, Rianne Riemens analyzes how the Sun has become a prominent element in the green marketing materials, or "tech-on-climate discourse", of Big Tech. The Sun is not only referenced as an important, green energy resource, it also serves as a key discursive element that draws a positive connection between the companies and the Sun. The solar dream that Amazon and Apple put forward misrepresents solar energy as infinite and immaterial resource. The chapter instead calls for stories that do not obfuscate the complex reality of solarity and the energy transition.
Architectural modernity in India Sources and perspectives for research. An introduction
Authors: Muhidine Éléonore
Published: July 2023

In this introduction, Eleonore Muhidine highlights the challenge of accessing visual archives of modern architecture in India. Born out of a need to locate visual sources on India's cities from Europe, this collection, which has brought together authors from various academic backgrounds to comment on it, also provides an opportunity to reflect on the material of the photographic postcard for 20th-century historical research. This European invention reflects colonial imaginaries, but also gives a glimpse into cities that have largely changed over the last few decades.
Image, recto, verso, context. Approaching Deltiology as a method
Authors: Kaden Ben
Published: July 2023

The article outlines the proposal for a methodological approach to the systematic study of picture postcards as historical social everyday media.
The Self and Its Avatars in Neuropsychiatry
Authors: Brugger Peter
Published: July 2023

In this article, Peter Brugger provides an overview of various reduplications of the own body and self as seen in neuropsychiatric practice. Duplications can be primarily visual or exclusively somaesthetic, depending on lesion location. Phenomenal detail matters, for instance whether handedness of one's double is maintained or reversed, whether the double is recognized as a second self or experienced as an uncanny shadow, or whether the localization of the observer's perspective is apparently detached from the own body. Such details inform neuropsychiatry of the intimate and tight relationships between body and self which are yet highly malleable in special circumstances
Engaging Consciousness. Time and Duration in Holly Bynoe's Compounds
Authors: Hezekiah Gabrielle A.
Published: July 2023

In this essay, Gabrielle A. Hezekiah reflects on the experience of time in the photo collages of Holly Bynoe. Taking a cue from Michel Poivert, Hezekiah both recognizes and moves beyond the social fact of decolonial representation in these images towards an investigation of the psychic fact of consciousness that is inherent in them. Drawing from the insights of Henri Bergson and Jean-Paul Sartre, the author suggests that Bynoe returns the viewer to a form of duration that one might call an archival present, allowing time itself to be imaged in consciousness.
Der unsichtbare Wohnraum
Authors: Fuhrhop Daniel
Published: July 2023

Viele Menschen suchen Wohnraum, doch Neubau löst das Problem nicht: Er ist teuer, verbraucht Fläche und belastet das Klima. Eine Lösung verspricht der »unsichtbare Wohnraum« - ungenutzte Zimmer älterer Personen nach Auszug der Kinder. Daniel Fuhrhop untersucht das Potenzial der Wohnsuffizienz anhand sozialer Programme wie der Vermittlung von Wohnpaaren nach dem Modell »Wohnen für Hilfe«, dem Umbau von Wohnungen, dem Umzug sowie sozialer Wohnraumvermittlung. Sein Fazit: Insgesamt können so jährlich 100.000 Wohnungen entstehen - ohne Klimabelastung und mit der Chance auf Nähe und Nachbarschaft.
Śmierć zwierzęcia w filozofii Toma Regana
Authors: Andrusiewicz Joanna
Published: July 2023

Przedwczesna śmierć samoświadomej istoty, nawet całkowicie bezbolesna, nie jest obojętna moralnie. I nie ma znaczenia, czy istota ta jest człowiekiem. Stanowisko to, nierzadkie dziś na gruncie animal studies, jako jeden z pierwszych przyjął i uzasadnił Tom Regan. W niniejszym artykule przedstawiono jego argumentację – opisano dwie najważniejsze zasady Stanowiska praw: Zasadę szacunku i Zasadę krzywdy oraz relacje między kategoriami podmiotów moralnych, obiektów moralnej troski i podmiotów życia. Zrekonstruowano i przeanalizowano problem etycznego wymiaru śmierci zwierzęcia, jako jednostki, naszkicowano też konsekwencje hipotetycznego przyjęcia Stanowiska Praw dla dopuszczonych dziś prawnie i powszechnie stosowanych praktyk wobec zwierząt pozaludzkich.
Coronary Ostial Acquired Occlusion or Congenital Atresia: An Ongoing Discussion
Authors: Sharma Divyansh , Prashar Abhisheik
Published: July 2023

Coronary ostial atresia is a developmental abnormality that typically causes asymptomatic anomalies in the coronary blood supply. This case report, which presents 2 symptomatic patients with right coronary artery abnormalities, explores difficulties in diagnosing coronary ostial atresia and distinguishing it from single coronary artery and coronary artery disease–related acquired occlusion. Factors underlying management decisions are also discussed.
The Difference Between Post-Laparoscopic Cystectomy Anti-Mullerian Hormone Levels In Endometrioma And Non-Endometrioma Cysts Patients
Authors: Kurniawan Cornelius Danu
Published: July 2023

Background: Endometrioma is a complex gynecological disease with increasing global prevalence. Laparoscopic cystectomy remains to be the primary choice of modality. Several studies, however, have revealed that laparoscopic cystectomy in endometriomas can cause ovarian damage and reduction in ovarian reserve. They demonstrated a decrease in serum AMH levels in endometrioma patients following laparoscopic cystectomyObjective: To identify the difference between the mean post-laparoscopic cystectomy AMH levels in endometrioma and non-endometrioma cysts patientsMethods: A prospective cohort study with 40 selected patients undergoing laparoscopic cystectomy in Kariadi General Hospital Semarang. They were divided into 2 groups of endometrioma and non-endometrioma cysts. AMH levels were measured before and after laparoscopic cystectomy surgery in both groupsResults: The mean age of endometrioma and non-endometrioma group were 32.40 ± 6.26 and 30.6 ± 3.69 years consecutively. The most common cysts were unilateral cysts with a diameter of > 4 cm which were dominated by endometrioma cysts. The group of subjects with endometrial cysts had lower AMH levels, both before (9.47 + 5.26 ng/mL) and after laparoscopic cystectomy (7.80 + 4.27 ng/mL). AMH levels before and after laparoscopic cystectomy in the endometrioma group showed a significant difference (p=0.004). In contrast, there was no significant difference in delta AMH between the non-endometrioma group (-1.63 + 4.12; p=0.685) and the endometrioma group (-1.74 + 2.37 ng/mL; p=0.685)Conclusion: Both endometrioma and non-endometrioma groups showed a decrease in AMH levels after laparoscopic cystectomy but they did not show a significant difference.
Liquid Smoke and Hydrogel Membrane as Burn Wound Healing Properties
Authors: Rayhan Amar
Published: July 2023

Background : Anyone has the potential to get injured, especially burns. Hydrogel membrane and liquid smoke are a combination of antibacterial, anti-inflammatory and antioxidant properties. These properties play an important role in wound healing. In wound healing, the re-epithelialization process is a critical parameter for the success of wound closure.Aim : Analyzed the effect of re-epithelialization length on burns of rats given a liquid smoke combination hydrogel membrane.Methods : Experimental research used post test only with control group design. The number of samples was 15 white wistar rats with burns which were divided into two treatment groups, namely P1 (liquid smoke combination hydrogel membrane), P2 (liquid smoke) and one control group K (hydrogel membrane). Assessment of reepithelialization length has been calculated using a microscope. Statistical test using One Way ANOVA – Post Hoc Bonferroni test.Results : The average length of re-epithelialization (µm) for each group was (P1) 2004.91, (P2) 1534.15 and (K) 1248.16. Based on the results of the One Way ANOVA analysis, we found p value  = 0.028 (p <0.05). This shows that there were significant differences in the data between groups.Conclusions : There was a significant difference on the length of re-epithelialization in rats burn wound between hydrogel membrane group with liquid smoke, liquid smoke group and control group.
Sikap dan Perilaku Pencarian Pelayanan Kesehatan Orang Tua dengan Anak Tuberkulosis saat Masa Pandemi COVID-19 di RSUD Al-Ihsan
Authors: Rausanfikra Syiffa Salsabila , Rakhmawati Windy , Hendrawati Sri , Maryam Nenden Nur Asriyani
Published: July 2023

Peningkatan kasus TBC saat pandemi COVID-19 karena isolasi sosial memicu penularan TBC di rumah akibat kontak erat selama isolasi. Hal ini menyebabkan keterlambatan diagnosis sehingga meningkatkan kejadian tuberkulosis. Sikap memiliki pengaruh besar terhadap terbentuknya perilaku pencarian pelayanan kesehatan orangtua dengan anak TBC. Penelitian ini bertujuan untuk mengetahui gambaran sikap dan perilaku pencarian pelayanan kesehatan orang tua dengan anak TBC di RSUD Al-Ihsan. Penelitian ini merupakan penelitian deskriptif kuantitatif dengan pendekatan retrospektif dan teknik purposive sampling. Kriteria sampel adalah orang tua yang memiliki anak dengan TBC sebanyak 67 sampel. Untuk mengukur sikap dan perilaku menggunakan kuesioner KAP Surveys yang dikembangkan oleh WHO. Analisis data pada penelitian ini menggunakan distribusi deskriptif  kuantitatif. Hasil penelitian sikap dengan reaksi orang tua ketika anaknya tertular TBC sebagian responden (50,7%) takut tertular TBC dan seluruh responden (95,5%) ketika anaknya tertular penyakit TB mengajak bicara dokter dan tenaga kesehatan. Adapun perilaku pencarian pelayanan kesehatan orangtua dengan anak tuberkulosis sangat bervariasi, lebih banyak responden yang memilih pusat kesehatan, segera ke pelayanan kesehatan setelah gejala TBC muncul dan faktor penghambat pergi ke layanan kesehatan adalah biaya, jarak, dan ketidaktahuan.  Sikap orang tua terhadap TBC sangat serius dan menganggap anaknya berpotensi dapat tertular penyakit TBC. Sikap ini sesuai dengan perilaku pencarian tempat pelayanan kesehatan. Penelitian selanjutnya diharapkan menganalisis determinan sikap dan perilaku orangtua anak dengan TB dalam mengakses pelayanan kesehatan.
Studi Kasus: Pertolongan Pertama Kegawatdaruratan pada Suspek Hipernatremia di Rumah
Authors: Poespodiwirjo Nur Hafizhah
Published: July 2023

Hipernatremia dapat menyebabkan kematian akibat gangguan cairan tubuh sehingga menimbulkan rusaknya sel-sel otak. Penelitian terkait penggunaan kalium dalam manajemen hipernatremia dan tatalaksana kasus hipernatremia pasien hipersensitif obat masih terbatas. Penelitian ini bertujuan untuk mendeskripsikan tindakan pertolongan pertama pada suspek hipernatremia yang hipersensitif obat. Studi kualitatif ini adalah studi kasus di bidang kesehatan (case report) yang merupakan bagian dari studi kasus tunggal. Partisipan dalam studi ini adalah seorang partisipan yang menjalani homecare. Adapun data dikumpulkan dengan melakukan anamnesis kepada partisipan dan menginterpretasikan tanda klinis yang muncul terkait hipernatremia. Data dianalisis menggunakan five analytic techniques. Seorang wanita berusia 48 tahun mengeluhkan sesak napas dan palpitasi setelah mengonsumsi jus celery untuk mengendalikan kadar kolesterol darahnya. Partisipan juga mengeluhkan adanya kelelahan yang juga merupakan tanda dari hipernatremia.  Partisipan diberikan oksigen 3 liter per menit per nasal kanul, larutan gula hangat, air putih dan tiga butir kurma. Setelah dilakukan intervensi, partisipan menunjukkan perbaikan kondisi berupa sesak napas dan dada berdebar-debar menurun. Hal ini menunjukkan kurma dapat dijadikan pertimbangan untuk pertolongan pertama pada hipernatremia di rumah sebelum partisipan mendapatkan penanganan lanjutan di rumah sakit. Penelitian selanjutnya diperlukan untuk menguji jumlah makanan tinggi kalium yang harus dikonsumsi secara tepat.
The Essex College of Medicine and Surgery: The Long Gestation, Troubled Life, and Early Death of New Jersey’s First Medical School
Authors: Chernesky Jason
Published: July 2023

Jason Chernesky reviewing The Essex College of Medicine and Surgery: The Long Gestation, Troubled Life, and Early Death of New Jersey’s First Medical School, by Sandra W. Moss.
Second Life of Post-Mining Facilities: Mines as a Tourist Attraction of Southern Poland
Authors: Hojka Zbigniew
Published: July 2023

The aim of this article is to present a tourist mining path located in southern Poland. This involves coal, silver, gold, salt, flint, chalk, uranium mines and oil wells. It includes some buildings connected with workers and mine-owners as well. These buildings were previously tied to mining. Currently, they function as museums or service-buildings.
Report from the 23rd International Congress of Historical Sciences Poznań 2020/2022 on 21–27 August 2022
Authors: Filipowska Karolina
Published: July 2023

XXIIIth International Congress of Historical Sciences 2020/2022 in Poznań.
The impact of test positivity on surveillance with asymptomatic carriers
Authors: Gaspari Mauro
Published: July 2023

Objectives

Recent studies show that Test Positivity Rate (TPR) gains a better correlation than incidence with the number of hospitalized patients in COVID-19 pandemic. Nevertheless, epidemiologists remain sceptical concerning the widespread use of this metric for surveillance, and indicators based on known cases like incidence rate are still preferred despite the large number of asymptomatic carriers, which remain unknown. Our aim is to compare TPR and incidence rate, to determine which of the two has the best characteristics to predict the trend of hospitalized patients in the COVID-19 pandemic.

Methods

We perform a retrospective study considering 60 outbreak cases, using global and local data from Italy in different waves of the pandemic, in order to detect peaks in TPR time series, and peaks in incidence rate, finding which of the two indicators has the best ability to anticipate peaks in patients admitted in hospitals.

Results

On average, the best TPR-based approach anticipates the incidence rate of about 4.6 days (95 % CI 2.8, 6.4), more precisely the average distance between TPR peaks and hospitalized peaks is 17.6 days (95 % CI 15.0, 20.4) with respect to 13.0 days (95 % CI 10.4, 15.8) obtained for incidence. Moreover, the average difference between TPR and incidence rate increased to more than 6 days in the Delta outbreak during summer 2021, where presumably the percentage of asymptomatic carriers was larger.

Conclusions

We conclude that TPR should be used as the primary indicator to enable early intervention, and for predicting hospital admissions in infectious diseases with asymptomatic carriers.
Analysis of multimedia technology and mobile learning in English teaching in colleges and universities
Authors: Liu Ruixia
Published: July 2023

Multimedia and mobile learning are effective teaching tools because of their many useful characteristics. Transmission of educational material to students is facilitated by technology in both multimedia and mobile learning environments. A more interesting and engaging learning experience may be achieved by combining text, graphics, music, video, and animation. Media-rich classrooms are often referred to as “multimedia learning.” In contrast, students who use mobile learning may access their courses from any place with an internet connection and a mobile device such as a smartphone or a tablet. Whenever this involves commonplace technological needs, its cellular gadget and notably its clever telephone take the cake. Smartphone gadgets have a very wide range of potential applications and uses. Some ethical considerations are preventing media from reinforcing stereotypes or prejudice in the communities where they are utilized. Student information are gathered and used in a way that protects their privacy, with materials required for students to engage in mobile learning, and respecting intellectual property and copyright regulations while using multimedia language-learning tools. This importance of learning cannot be overstated but when such results come, mobile devices have increasingly been used in schools. This question of whether mobile devices have an impact on education remains open. Because of such “mobile gaining knowledge,” along with an overall phrase describing researching where different devices could be utilized in combination to enhance schooling, mobile devices had become more popular. Because today’s kids utilize their mobile devices frequently, studies on their effect on word learning are immediately required. This pilot research seeks to understand why school learners think via smartphone-based L2 exercises. In particular, this study collects data about several plenty applications using cell phones in linguistic research. Two hundred and ninety-four college children from one top Turkish institution participated in this research. This project uses some hybrid reporting models and relies on description analysis over its methodology. Their results show that users place one high value on obtaining ready accessibility to materials while studying some foreign language. Respondents not only remarked about their cellphone’s portability but also proposed new applications for enhancing their learning in other countries.
Oil displacement properties of surfactin: a comparative study
Authors: Degang Lucas , Auricchio Gabriela , de Oliveira Schmidt Vanessa Kristine , Della-Flora Isabela Karina , Andrade Cristiano José de
Published: July 2023

Biosurfactants are amphiphilic compounds synthesized from plants and microorganisms and are known for their high biodegradability, low toxicity, and eco-friendliness. They have diverse applications in industrial and environmental fields, including oil recovery, bioremediation, and cleaning up hydrocarbons from polluted areas. Surfactin is a potent lipopeptide biosurfactant produced by Bacillus subtilis bacteria. In this study, we produced surfactin by B. subtilis using cassava wastewater as the fermentation medium. This production was monitored by high performance liquid chromatography (HPLC). Approximately 600 mg L−1 of surfactant was produced. The oil displacement test was then performed to evaluate the effectiveness of crude and purified surfactin compared to a synthetic surfactant and a biosurfactant. Three types of surfactants were tested: the synthetic surfactant sodium lauryl sulfate (SDS), the commercial biosurfactant rhamnolipid (Rh), and surfactin in its crude form and purified one – after acid precipitation. The analysis results indicated that surfactin, in both its crude and purified forms, was more effective at dispersing oil than the other surfactants tested, even at lower concentrations. This suggests that biosurfactants have great potential as a more sustainable and effective alternative to petroleum-derived synthetic surfactants. Surfactin can be applied without the need for downstream processes.
Comparing Acute Responses Between Single Session Circuit Training and Fireground Suppression Tasks
Authors: Loewen Brandon , Melton Bridget , Maupin Daniel , Ryan Greg
Published: July 2023

Loewen, B, Melton, B, Maupin, D, and Ryan, G. Comparing acute responses between single session circuit training and fireground suppression tasks. J Strength Cond Res 37(8): 1667–1678, 2023—The purpose of this study was to compare the cardio-metabolic and perceived demands of task-specific circuit training to fireground suppression tasks (FST). Twenty-three career, structural firefighters performed three separate testing days (i.e., FST, CT, and CTW). FST consisted of performing seven common occupational tasks in full gear (∼22.5kg). The weighted (CTW: 18.9kg vest) and unweighted (CT) circuit utilized seven exercises designed to mimic the FST's. Measurements included relative heart rate (%HRmax), post-training blood lactate (Lapost), change in countermovement jump height (▵CMJ), change in dominant and non-dominant handgrip strength (▵DHG and ▵NDHG), total training time, rating of perceived exertion (RPE), and job-specific rating of relevance. A repeated measure analysis of variance (ANOVA), with Bonferroni post-hoc, was performed for each variable, excluding RPE and rating of relevance. Friedman's ANOVA was used to assess differences in RPE and rating of relevance, with Wilcoxen Signed Rank tests follow-up. Significant mean differences were found in %HRmax between CT and FST (∼8.6%, p < 0.01, d = 1.12) and CTW and FST (∼5.3%, p < 0.01, d = 0.75), ▵CMJ between CT and FST (p < 0.01, d = 1.35) and CTW and FST (p < 0.01, d = 1.09), ▵NDHG between CTW and FST (p = 0.01, d = 0.79), training time between CT and FST (p < 0.01, d = 1.00) and CTW and FST (p < 0.01, d = 1.81), and rating of relevance between CT and FST (PS
dep = 0.67). In conclusion, CT and CTW were able to elicit similar metabolic and perceived demands as FST, while producing a lower cardiovascular response. Therefore, while circuit training may be a beneficial training tool for firefighters, it cannot replicate FST.
Intentionally Slow Concentric Velocity Resistance Exercise and Strength Adaptations: A Meta-Analysis
Authors: Hermes Matthew J. , Fry Andrew C.
Published: July 2023

Hermes, MJ and Fry, AC. Intentionally slow concentric velocity resistance exercise and strength adaptations: a meta-analysis. J Strength Cond Res 37(8): e470–e484, 2023—Intentionally slow-velocity resistance exercise (ISVRE) is suggested by some to be equally or more effective than fast or traditional velocities for increasing muscular strength. The purpose of this meta-analysis was to assess the effect ISVRE has on strength adaptations compared with faster or traditional velocities, with subgroup analyses exploring age, sex, and training status as confounding factors on the influence of velocity on strength adaptation. Eligible studies (n = 24) were required to be chronic (multiple weeks) randomized or nonrandomized comparative studies using dynamic constant external resistance for training and testing, and pre-post strength assessments. All studies examined healthy individuals (n = 625; fast or traditional n = 306, intentionally slow n = 319). A random-effects meta-analysis indicated a significant (p ≤ 0.05) effect in favor of fast training (effect size [ES] = 0.21, 95% confidence interval [CI] = 0.02–0.41, p = 0.03). Publication bias was noted through trim and fill analysis, with an adjusted effect size estimate of 0.32 (p < 0.001). Subgroup analyses indicated no difference between trained and untrained subjects (QM = 0.01, p = 0.93), and no difference between older and younger subgroups (QM = 0.09, p = 0.77), despite younger favoring faster (ES = 0.23, p = 0.049) and older not favoring either velocity (ES = 0.16, p = 0.46). Subgroup analysis also indicated women favored faster training (ES = 0.95, p < 0.001) in comparison to men (ES = 0.08, p = 0.58). Contrary to some previous reviews, these results indicate that chronic fast or traditional velocity resistance exercise increases muscular strength to a greater degree than ISVRE training. Resistance training velocity must be considered if strength is a desired outcome.
A Research Note on Relationships Between Age, Body Size, Strength, and Power With Throwing Velocity in High School Water Polo Players
Authors: Lockie Robert G. , Wakely Alexander M. , Viramontes Erika , Dawes J. Jay
Published: July 2023

Lockie, RG, Wakely, AM, Viramontes, E, and Dawes, JJ. A research note on relationships between age, body size, strength, and power with throwing velocity in high school water polo players. J Strength Cond Res 37(8): e466–e469, 2023—A successful high school strength and conditioning program should aim to improve fitness and develop motor skills in athletes. This research note investigated the relationships between throwing velocity with age, height, body mass, strength, and power in male high school water polo athletes. Fifteen (n = 15) water polo athletes (age: 15.67 ± 0.98; height: 177.63 ± 6.53 cm; body mass: 78.07 ± 16.08 kg) from one high school program were recruited. Strength was measured using combined grip strength from both hands and a leg/back dynamometer. Power was measured by a vertical jump and 2-kg seated medicine ball throw (MBT). Subjects also threw a water polo ball with maximum effort to measure throwing velocity. Pearson's correlation and stepwise regression were used to calculate relationships between throwing velocity with age, body size, strength, and power (p < 0.05). Age (r = 0.530), grip strength (r = 0.674), leg/back strength (r = 0.699), and the MBT (r = 0.670) all showed significant positive relationships with throwing velocity. Leg/back strength predicted throwing velocity with 49% explained variance (r

2
= 0.490, p < 0.004). With age, explained variance increased to 66% (r

2
= 0.664, p < 0.001). Throwing velocity related to age, which could be expected with maturation. However, stronger relationships were seen for upper-body (grip) and lower-body (leg/back) strength, and upper-body power (MBT). Strength and conditioning programs for high school athletes who develop upper- and lower-body strength and upper-body power could enhance throwing velocity among water polo (and potentially other overhead throwing) athletes.
Salivary Testosterone and Cortisol Changes During a Game in Professional Male Basketball Players
Authors: Cabarkapa Dimitrije , Eserhaut Drake A. , Cabarkapa Damjana V. , Philipp Nicolas M. , Fry Andrew C.
Published: July 2023

Cabarkapa, D, Eserhaut, DA, Cabarkapa, DV, Philipp, NM, and Fry, AC. Salivary testosterone and cortisol changes during a game in professional male basketball players. J Strength Cond Res 37(8): 1687–1691, 2023—The purpose of this study was to examine acute changes in salivary testosterone (T), cortisol (C), and testosterone-to-cortisol ratio (T/C) during a simulated 5-on-5 basketball game. Seven professional male basketball players volunteered to participate in this study. Repeated-measures analysis design was used to examine changes in hormonal concentrations across 8 testing time points: immediately upon arrival to the gymnasium-baseline (BS); post–warm-up (PW); post-first (P1Q), second (P2Q), third (P3Q), and fourth quarter (P4Q); and 30 (P30) and 60 minutes (P60) postgame. The findings of this study indicate that a simulated 5-on-5 basketball game provoked significant changes in salivary T, C, and T/C. When compared to the BS levels (x̄ ± SD [nmol·L−1]; 6.72 ± 2.53), salivary C concentration experienced a notable increase P3Q (16.20 ± 7.70) and remained elevated throughout the rest of the sampling periods, with values failing to return to BS levels P60 (11.88 ± 5.58). Conversely, a significant increase in salivary T occurred P1Q (0.76 ± 0.21) when compared to the BS levels (0.58 ± 0.12) and remained elevated up to P30 (0.75 ± 0.20), with values returning to BS levels P60 (0.63 ± 0.14). In addition, despite no significant intragame alterations, T/C exhibited a notable decrease P30 (0.06 ± 0.02) and P60 (0.07 ± 0.04), when compared to BS values (0.10 ± 0.04). Overall, these findings provide additional insight into the physiological stress that basketball players are exposed to during 5-on-5 competitive play and can be used to appropriately adjust and monitor training loads to optimize recovery and on-court basketball performance.