bluuebunny/crossref_metadata_2025 huggingface dataset:
Prediction of antitumor activity of 3-substituted quinazolinone derivatives synthesized in one-pot method catalyzed by Bi(OTf)3
Authors: Perekhoda L. , Hari Krishna M. , Sekhar T. , Venkateswarlu A. , Thriveni P. , Suleiman M. , Semenets A. , Fedosov A. , Grinevich L. , Kobzar N. , Yaremenko V.
Published: March 2022

A series of 3-substituted guinazolinone derivatives have been synthesized in good to excellent yields and high selectivity by one-pot reaction using anthranilic acid, amine and orthoester in ethanol under mild conditions, respectively. The reaction was efficiently promoted by Bi(OTf)3 and the catalyst could be recovered easily after the reactions and reused without evident loss of reactivity. Docking studies have shown that the tested molecules have an affinity for anticancer targets. The data obtained can be used in planning experimental screening for antitumor activity.
Prevalence of Urinary bacterial colonisation in women seeking Obstetrical and Gynecological support at a secondary care centre in South India
Authors: Pandian Devamani , Abraham Jayanthi
Published: March 2022

Asymptomatic bacteriuria is the presence of bacterial strains in urine samples obtained from a person without revelation of any symptoms of urinary infections. During pregnancy, women are prone to suffer from urinary tract infection at much higher rates due to certain physiological alterations. Thus, the awareness amongst women to protect themselves from asymptomatic bacteriuria and its risk factors are much required. The aim of this study was to determine the predominant uropathogens and their antibiotic susceptibility pattern isolated from women attending the outpatient department in Sri Narayani Hospital and Research Centre. Group of 350 patients were routinely checked. Urine samples of the patients were routinely collected and checked for presence of pathogenic bacteria. The microbes obtained were studied thoroughly to determine their pathogenicity. Antibiotic susceptibility ability of the organisms was studied to detect the resistance of the strains against the drugs used for the treatment. Escherichia coli and Klebsiella sp. were the two most predominantly found pathogens in the urine samples of patients suffering from asymptomatic bacteriuria.
Eight weeks consumption of high-fat diet promotes Mesenteric fat deposition when compared to other rat diets
Authors: Azwan Khairil , Mona Resni , Firdous Jannathul , Keumala Sari Dina , Rosie David Pamela , Muhamad Noorzaid
Published: March 2022

Metabolic syndrome is a grouping of several medical conditions plaguing the modern world today. Excessive visceral fat is strongly associated with abdominal obesity which is one of the characteristics of metabolic syndrome. In general, an unbalanced, rich diet plays an important role in the proliferation of adipocytes. Our aim is to observe which diet contributes to the deposition of visceral fat such as the mesenteric fat. For eight weeks, thirty-five Sprague Dawley rats were divided into five groups and were fed five different types of diets. The five diets are normal rat chow, high sugar, high starch, high protein and high fat rat (palm oil-based) feed formula. Besides the formularized rat feeds, the rats were given tap water ad libitum. The result showed high fat diet promotes mesenteric fat proliferation when compared to other rat feed formula. Present study showed that high-fat diet promotes mesenteric fat proliferation when compared to other diets.
Quantitative determination of trace amounts of Diethylhexyl phthalate content in Dextrose injection proficiently by a simplistic Gas Chromatography Technique
Authors: Ramakrishna Reddy H. , Pratap S. R. , Chandrasekhar N. , Mohamed Shamshuddin S. Z.
Published: March 2022

The objective of present study was to analyze Diethylhexyl phthalate content in 5% Dextrose injection and other reconstituting diluents for pharmaceutical injectable formulations. Reconstituting diluents for pharmaceutical injectable formulations are mainly stored and supplied in polyvinyl chloride bags. This may lead to leaching of Diethylhexyl phthalate, a toxic content from polyvinyl chloride bags into reconstituting formulations. In the current study, a proficient and simple method by using a Gas Chromatograph was developed and validated for the quantitation of trace amounts of Diethylhexyl phthalate in 5% Dextrose injection. The method was optimized by using silica fused short capillary column (DB-1; USP G2 phase) with dimensions 5 m length x 0.53 mm inner diameter and 2.65µm film thickness. The method involves a simple extraction procedure for sample preparation by means of extraction with n-Hexane solvent and evaporation with a stream of nitrogen gas. An Internal standard (1-Phenydodecane) was added to standard and sample preparations by using n-Hexane as diluent. The method was validated as per the current regulatory guidance for analytical method validation.The projected methodology was found to be selective, accurate, precise, and linear in the test concentration range from 0.004 µg/mL to 5.065µg/mL for Diethylhexyl phthalate. The method was effectively used to analyze the Diethylhexyl phthalate content in 5% Dextrose Injection and other reconstituting diluents for pharmaceutical injectable formulations.
Green Solvent Assisted UV-Spectrophotometric Method for Estimation of Rosuvastatin in Bulk and Pharmaceutical Dosage Forms
Authors: Patil Arpana , M. Maste Meenaxi , S. Suryawanshi Shailendra , Patil Nikita
Published: March 2022

Objectives: The goal of this study is to create and test a UV-Spectrophotometric method for estimating Rosuvastatin in bulk and pharmaceutical dosage forms utilizing a green solvent. Method: Development of UV-Spectrophotometric method was carried out by using 2% Sodium Lauryl Sulfate solution as green solvent. Rosuvastatin was detected at a wavelength of 242nm. According to ICH guidelines, the developed technique was verified in terms of linearity, precision, repeatability, limit of detection, limit of quantification, accuracy, and robustness. Rosuvastatin in pharmaceutical dose forms was successfully estimated using a newly developed and verified approach. Results: Rosuvastatin has a maximum absorption wavelength of 242nm. In the concentration range of 5-25µg/ml, Beer's law was followed. The detection and quantification limits were found to be 1.58µg/ml and 4.79µg/ml, respectively. The recovery of Rosuvastatin Calcium in tablet form was found to be between 97 and 102 percent. All of the precision and repeatability results fell within acceptable limits. Rosuvastatin was tested and found to be 98.88%. Conclusion: The method was found to be simple, environment friendly, reproducible and economical and can be used for routine analysis of Rosuvastatin in bulk and pharmaceutical dosage form. The 2% Sodium Lauryl Sulfate solution can be used as Green solvent.
Synthesis and Biological Evaluation of novel R1, R2 substituted
2-(4-((2-(4-alkoxyphenyl)-5-methyloxazol-4-yl)methyl)-1-alkyl-5-methyl-1H-pyrazol-3-yloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol having Anti Diabetic activity
Authors: Vaddiraju Nagesh , Ajitha M. , Rajnarayana K. , Godela Ramreddy
Published: March 2022

The synthesis and biological evaluation of novel pyrazole based heterocycles attached to sugar moiety lead to creating a new molecular frame work. Nine new compounds were synthesized by reacting ethyl 2-((2-(4-methoxyphenyl)-5-methyloxazol-4-yl) methyl)-3-oxobutanoate derivatives (9a-9c) with different alkyl hydrazines to give various substituted 4-((2-(4-methoxyphenyl)-5-methyloxazol-4-yl) methyl)-5-methyl-1H-pyrazol-3-ol derivatives (10 a-10i) which in turn were reacted with bromoglucose (3)to yield R1, R2 substituted 2-(4-((2-(4-alkoxyphenyl)-5-methyloxazol-4-yl)methyl)-1-alkyl-5-methyl-1H-pyrazol-3-yloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (12a-12i). The chemical structures of the synthesized compounds were characterized by means of IR, Mass and NMR spectroscopy. The compounds were screened for anti-diabetic activity by urinary glucose excretion method (UGE). Among the compounds tested, 12f, 12h and12i have exhibited moderate anti-diabetic activity as that of standard drug, remogliflozin. These compounds can be further exploited to get the potent lead compound.
A Study of Nutritional Status and Prevalence of Anaemia among the Adolescent girls and Women of Reproductive age of Baigatribe accessing Antenatal Clinic in Public Health Sector in Chhattisgarh, India
Authors: Chakravarty Moyna , Venugopal Reeta , Chakraborty Anuradha , Kumar Mehta Sunil , Varoda Aniksha
Published: March 2022

Nutritional problems have serious health implications impacting physical development, psychological, behavioral and work performance of an individual. Anaemia is the most common problem among pregnant and lactating women in most of the developing countries. Anemia during pregnancy is the most common preventable causes of maternal morbidity and poor prenatal outcome. Healthy growth and development of a girl through adolescence helps to prepare her for healthy pregnancies during child bearing years. Prevalence of anemia in India is very high across all groups. The present study was conducted to assess the levels of anaemia and nutritional status among the Baiga women and adolescent girls residing in three districts of Chhattisgarh. Only 42% of the Baiga women, of reproductive age, were found to have normal levels of anemia while 58% of them were found to be anaemic. Prevalence of anaemia was found to be very high among adolescent Baiga girls. Only 5.3% adolescent Baiga girls were found to have normal levels of Hb while 94.7% had various degrees of anaemia, putting them into high risk zones for the future pregnancies. Majority of the Baiga women respondents i.e. 47.33% had low BMI between16-18.5 which falls as under nutritional category, 6.67% were very severely underweight and only 40.66 % of the respondents could be categorized under the normal category of Body Mass Index (BMI). BMI among adolescent girls when compared to WHO 2004 standard of malnutrition revealed that 27.2% girls could be classified under the normal category, 24.2 % girls suffered from mild thinness, 17.8 % girls suffered from moderate thinness and 30.8% girls suffered from severe thinness category of malnutrition.The strategy of increasing iron intake in every households through dietary diversifications and use of iron fortified iodized salts, providing IFA supplementations to vulnerable groups, testing and timely treatment of pregnant women and adolescent girls with anaemia, is required to accelerate the pace of reduction in the prevalence of iron deficient anemia to enable the country to achieve SDG target for the reduction of anaemia.
Immunomodulatory effects of Pediococcus acidilactici on BALB/C mice Immunosuppressed by Cyclophosphamide
Authors: N. Ali Ekhlass , A. Kadhem Ashwaq , Zuheir Majeed Huda , M.B. Muhsin Yusra , Ali Ajah Hamzia
Published: March 2022

Background: The live microorganisms that present in food in addition dietary supplements called Probiotics they have beneficial effect in the human intestine. In the last years, Probiotics has become within treatment options for several disease included immune system. The advent and use of probiotics seem to be increasing day by day all over the world. Objective: The current study included detection of efficacy Pediococcus acidilactici as immunomodulatory in mice that treated with cyclophosphamide. Design: To detect efficacy of Pediococcus acidilactici as immunosuppressive model was used. This model was completed by taking 20 male BALB/C mice with six-weeks old to divide into (5) groups :(G 1) group is the normal control. (G2) group: the group that injected with cyclophosphamide. (G3) group: the immunosuppression plus Pediococcus acidilactici (6×108 CFU/ml). (G4) group: the immunosuppression plus Pediococcus acidilactici (6×104 CFU/ml). last (G5) group : is the group that treated with probiotics. Results: In the current study, thymus and spleen indicators were significantly higher in treated groups than those of (G1) group (NC) with (0.323±0.34) (P<0.05), also Macrophages phagocytosis showed a clear increase in the three treated groups (76.625±108, 72.125±1.65, 87.750±1.32) respectively with significantly (P<0.05), as a compared with (G1) group (NC). Conclusions: The current study reveals the ability of Pediococcus acidilactici (6×109) CFU/ml to accelerate the healing of cyclophosphamide immunosuppressive mice. So, the activity role of probiotic strain as immunomodulator in this study leads us to urge the use it as an alternative treatment for chemical drugs that used against immunosuppression.
A Clinical Study to Evaluate the Safety and efficacy of Pachai Karpoora Vadagam (Internal Medicine) and Vaeppa Ennai (External Medicine) on Azhal Keel Vayu (Osteoarthritis)
Authors: S Shunmugaram , Kumar N J Muthu , V Mahalakshmi , M V Mahadevan , D Periyasami , P Samundeeswari
Published: March 2022

An open clinical trial conducted to access the safety and efficacy of Pachai Karpoora Vadagam (PKV) and Vaeppa Ennai (VE) in the management of Azhal Keel Vayu (AKV) is one among 10 types of Keel Vayu diseases particularly occurring in joints. The trial was conducted at OPD/IPD of Ayothidoss Pandithar Hospital, in accordance with the standard study protocol duly approved by the Institutional Ethics Committee (IEC) of National Institute of Siddha. The clinical study is registered in Clinical Trials Registry – India. Duly signed informed consent was obtained from every patient before trial enrollment. Among 40 subjects, 20 subjects were treated on OPD basis and remaining 20 subjects were admitted in IPD for 48 days. Trial subjects were screened and documented by the standard screening proforma. Universal pain assessment scale was used to assess the trial outcome. Clinical assessment was done on every 7th day and prognosis was noted in the prescribed proforma, daily in IPD subjects. Paired‘t’ test was used to test the significance of treatment. The study revealed statistical significance of pain score before and after treatment of Pachai Karpoora Vadagam (PKV) and Vaeppa Ennai (VE) (p <0.001). There are no significant statistical changes of safety parameters such as Liver Function Test and Renal Function Test before and after treatment. Hence it is concluded that the drugs are safe and effective in the management of AKV (Osteoarthritis).
Identification of Bioactive Compounds Present in Kulthi (Macrotyloma uniflorum) Seed Extract by Gas Chromatography-Mass Spectrometry
Authors: Abdullah Basheer Mohammed , Jaleel A.H Abdul , Fatema Shaikh Ifrah , Pathan Jiyaullakhan Maulakhan
Published: March 2022

The objectives of this research were to determine the chemical composition of the extract of Macrotyloma uniflorum seeds by using Gas chromatography–Mass Spectrometry analysis (GC-MS). GC-MS is a matchless method to study and measure the quantity of organic volatile and semi-volatile compounds. Gas chromatography is employed to separates mixtures into individual components employing a temperature-controlled capillary column. Mass spectrometry is utilized to recognize a variety of components from their mass spectra. In the present study, volatile/semivolatile compounds present inM. uniflorum seed extract were analyzed. M. uniflorum seed extract isextracted by the soxhlet extraction method and then analyzed by GC-MS. A total of 28 compoundswere found and quantified in this study. The major bioactive compounds in M. uniflorum seed extract are: 1,7-Octadiyne, 1-Propanone, 1-phenyl-3-[2-( phenylmethoxy)phenyl] -(16.93%), Benzene, 1-methyl-4-(1,2,2-trimethylcyclopentyl)-, (R)-, Benzene, 1-(1,5-dimethyl-4-hexenyl)- 4-methyl- (13.88%) and à-Farnesene, 1,3,6,10-Dodecatetraene, 3,7,11-trimethyl- (Z,E)- (12.68%). The present investigation revealed that M. uniflorum was composed of variety of metabolites and therapeutic active substances as well as novel substances. These substances could be isolated and further empirically evaluated to confirm their biologic and medicinal activities as well as investigate their mechanism of action.
Corroboration of Obesity and its Complications with Oral Disorders in Children and Adolescents: A Literature Review
Authors: M Suganya , Prabakar Sibikar , Rao US Mahadeva
Published: March 2022

Pediatric obesity is a major global concern. Obesity in childhood and adolescence is associated with both physiological and psychological comorbidities, which have been well described, and severe obesity is associated with a higher degree of risk. The World Health Organization (WHO) has recognized obesity as a predisposing factor to measure chronic diseases ranging from cardiovascular diseases to cancer. Once considered a problem only in wealthy countries, WHO estimates show that overweight and obesity are now dramatically on the rise in low and middle income countries. The disturbing sequelae of this increased trajectory of overweight populations are the parallel increases in chronic diseases that are co-morbidities of obesity. Primary health care providers, including dental professionals, are well-positioned to address this public health problem at the patient level. Dental professionals must be aware of the increasing numbers of the obese patients and of the significance of obesity as a multiple risk factor syndrome for oral and overall health. Dental professionals have a crucial role in the prevention and detection of many oral and systemic diseases because of their diagnostic and screening abilities as well as the frequency of patient visits. Ultimately, a health condition as prevalent and serious as obesity must be approached by a concerted and collaborative effort of many disciplines and organizations. The dental profession should include itself in this collaboration using the tools and education opportunities available. Although the connection between oral health and obesity is critical to understand, it should not be the sole motivating factor for taking action.
Evaluation of Toxicity and Antidiabetic Activity of Ethanolic Extract of Flowers of Moringa oleifera against Dexamethasone Induced Hyperglycemia in Albino Wistar Rats
Authors: Mujalde Pushpraj , Jain Sourabh , Shukla Karunakar
Published: March 2022

Diabetes is a defect in the ability of the body to convert glucose (sugar) to energy. Glucose is the main source of energy in our body. When food is digested it is metabolized into fats, proteins, or carbohydrates. Glucose is then transferred to the blood and is used by the cells for energy production. To investigate the antidiabetic effect ethanolic extracts of flowers of Moringa oleifera against dexamethasone-induced insulin resistance in wistar albino rats. To study the antidiabetic effect, flowers of Moringa oleifera were collected and authenticated, extracted and investigated for acute toxicity and dexamethasone induced hyperglcemia. The animals treated with EEMOF at a dose of 100mg/kg and 200mg/kg prevented the development of hyperglycemia, hypercholesteremia and hypertriglyceridemia in dexamethasone induced insulin resistance models. Oral administration of Moringa oleifera 100mg/kg and 200mg/kg reduces serum glucose, triglyceride, total cholesterols and LDL concentration and improve the concentration of HDL in dexamethasone administered rats. The lignin Moringa oleifera showed significant anti-diabetic effect in rats after oral administration. The present study demonstrated that Moringa oleifera could be useful in Management of diabetes associated with abnormalities in lipid profiles. Further study need to isolate, identify the active compounds and find out the possible mechanism of actions.
ADHERENCE TO TREATMENT AMONG HYPERTENSIVE PATIENTS AS A RESULT OF SPECIALISED PHARMACEUTICAL CARE
Authors:   Department of Organization and Economics of Pharmacy, Faculty of Pharmacy, Medical University - Varna, Bulgaria., Ivanova Mariya , Todorova Anna ,   Department of Organization and Economics of Pharmacy, Faculty of Pharmacy, Medical University - Varna, Bulgaria., Georgieva Lora ,   Department of Social Medicine and Healthcare Organization, Faculty of Public Health, Medical University - Varna, Bulgaria., Pesheva Magdalena ,   Department of Organization and Economics of Pharmacy, Faculty of Pharmacy, Medical University - Varna, Bulgaria.
Published: March 2022

Arterial hypertension (AH) is one of the main risk factors for cardiovascular diseases and mortality among the population. Major problems in treating hypertension are the lack of adherence and poor blood pressure control. Purpose: To study the level of adherence to pharmacotherapy among hypertensive patients after the provision of specialised pharmaceutical care. Materials/Methods: Pharmaceutical care has been provided through a custom-made algorithm for consulting hypertensive patients, designed by the authors. Community pharmacists, involved in the study, have been trained in advance to provide specialised pharmaceutical care to hypertensive patients. A direct anonymous questionnaire has been delivered to hypertensive patients. The questionnaire consists of two parts. The first part includes questions about demographic details, lifestyles, the frequency of blood pressure measurement, etc., and the second part is a validated tool - the Morisky Medication Adherence Scale. Results: The study involved 50 patients with AH: 53% women and 47% men. After pharmaceutical care was provided through the established algorithm, 84% of the surveyed patients reported having no difficulties in the use of the prescribed medicines, and only 16% reported difficulties. Good management of blood pressure was observed in 73% of the respondents, while poor control was reported in only 27%. The Morisky coefficient for the study group was3.74, at a maximum score of 4, where the score for men was3.75 and for women – 3.72. Conclusions: The studied sample group shows a very high level of adherence to the treatment and hence good blood pressure control. It can be assumed that the achieved outcomes are due to the specialised pharmaceutical care performed in accordance with the established algorithm.
Exploring the Degree of Awareness of Teachers Regarding the Use of Multimodality and Its Influence on Online Teaching: A Case Study of Online Teaching before and during COVID-19 in Kuwait
Authors: Alsalim Monirah Saad , Al-Eidan Ayda A , Zeyab Alaa Jaber
Published: March 2022

Teaching and learning took place differently before and during the COVID-19 pandemic. The pandemic changed the way people lead their lives – switching from traditional teaching (face-to-face) in a public setting to online teaching due to social distancing. The teaching system was forced to accommodate distance learning during COVID-19 to complete academic studies. As a result, some Gulf countries found it difficult to implement distance learning and blended learning due to a lack of infrastructure and other challenges and difficulties. In online teaching, to adequately meet the individual needs of students, effective communication and cooperation between the teacher and the student is required. Thus, this research seeks to determine the differences in teaching and learning during COVID-19. The major aim is to determine how teaching and learning occurred before COVID-19 and how effective they were during COVID-19. This paper studies teachers' use of multimodality in teaching and their perceptions, knowledge, and experiences before and during COVID-19. It also explores the implications and impact of using multimodality in teaching in line with technology before and during COVID-19. Additionally, it investigates the opinion of the teachers regarding their students' interpretation and interaction with multimodality.
Constitutional Provisions for Right to Education in the Indo-Nepalese Context: Gap between Policy and Practice
Authors: Pathani Digvijay Singh , Deupa Madan Singh
Published: March 2022

AbstractThis study aims at comparatively identifying the constitutional provisions for right to education, their implementation and impact on education in India and Nepal. This is an analytical descriptive study based on document analysis. By the mid of 2011, 81% constitutions of the world guaranteed or aspired to protect the right to primary education. Nepal and India both have clear constitutional provisions for right to free and compulsory basic education but are unable to fulfil the international and national educational commitments and goals. India and Nepal fall in 2nd and 48th rank respectively based on population in the world in 2018. However, educational indicators indicate that both the countries could not ensure the educational access to all the children. In the year 2014-15, 22.131 million children were either not enrolled or did not complete primary education in India. This number was 270 958 in Nepal in the same year. Results show that there is a wide gap between the educational policies and their actual implementation in India and Nepal.
The Arab World and the Language of Politics
Authors: Qabani Abdullah
Published: March 2022

Language society and politics are terms, which are interchangeably important. Those three terms are linked in a way that is beyond separation or argument when it comes to analyzing discourse in general and political discourse in particular. Through language, society can deliver politics and impose beliefs and ideologies. The relationship between Arabs in general and politics has been a source of questions for decades due to many reasons. These reasons vary between social and historic reasons. This study aims to discuss and track how Arab writers and scholars looked at politics in their writings and how they perceived its importance and role starting with the early Islamic era and ending with our current days. It has been found that there is an apparent and close relationship between politics and religion. Further, it has been noticed that the political discourse delivered by Arab leaders has not received proper attention in terms of its effect on the different Arabic societies and the different political events that took place throughout the post-colonialism era.
Educational demographics of orthopaedic surgery department chairs
Authors: Clark Sean C. , Miskimin Cadence , Mulcahey Mary K.
Published: March 2022

Background

Becoming chair of an academic clinical department is a tremendous achievement that takes many years of experience and clinical excellence.

Objective

The purpose of this study was to determine the educational demographics of current orthopaedic surgery department chairs in the United States.

Methods

A complete list of orthopaedic surgery residency programs was obtained from the Accreditation Council for Graduate Medical Education (ACGME) 2019-2020 list of residency programs. Department chairs were identified through an online search. Educational data, including where the department chair went to medical school, residency, fellowship, and type of fellowship completed were obtained.

Results

A total of 145 orthopaedic department chairs were identified. The most attended medical schools by department chairs were Baylor (6 of 145, 4.1%) and Northwestern (6 of 145, 4.1%). The University of Rochester was the most common orthopaedic residency attended (9 of 145, 6.2%) and Harvard was the most common orthopaedic clinical fellowship (20 of 133, 15.0%). On average, it took 17.9 years from completion of clinical training to being named department chair.

Conclusion

This study provides insight into the academic credentials, length of clinical experience, and research productivity of current orthopaedic surgery department chairs. Certain training programs may be more likely to produce department chairs and, in general, an orthopaedic surgeon is more likely to become chair at an institution where he/she previously trained. Finally, research productivity is clearly an important factor in becoming chair, as most chairs have high h-indices and a consistent track record of research excellence.
Hill-Sachs Deformity
Authors: Jeong Jae Yun , Stead Thor , Kwon Jenna , Carman Matthew , Ganti Latha
Published: March 2022

The authors present the case of a young man who sustained a Hill Sachs lesion resulting in recurrent shoulder dislocations. The presentation, radiographic findings, management and prognosis are discussed.
Arthroscopic Lateral Collateral Ligament Repair for the Acute Elbow Dislocation in Primary Lateral Sclerosis Patient: A Case Report
Authors: Mahasupachai Nattakorn , Premsiri Arnakorn , Chanlalit Cholawish
Published: March 2022

Introduction

Without adequate muscle function as the dynamic elbow stabilizer, in a patient with a neuromuscular disorder, such as primary lateral sclerosis (PLS), the osteoligamentous structures are the only elbow stabilizers. To provide elbow stability, these structures should be restored.

Case

A 30-year-old female with PLS suffered from pain and dysfunction of her elbow after a previous elbow injury and current elbow dislocation.

Management and outcomes

We performed an arthroscopic lateral collateral ligament repair. At 6 months postoperative, her elbow gained stability and a painless full range of motion.

Conclusion

Periarticular muscles are crucial in joint congruity maintenance when the static stabilizers are disrupted. However, in neuromuscular diseases, the dynamic stabilizers are inadequate in providing stability for ligament healing, causing elbow instability. Osteoligamentous stabilizers restoration is the key to joint stability in a paralytic limb. An arthroscopy is a good option restoring collateral ligaments by reducing damage to surrounding muscles.
The Effectiveness of a Behavioral Program in Reducing the Aggressive Behavior of Children with Mild Mental Disabilities at the Mu’tah Center for Special Education
Authors: Alremawi Sameer , Arabiyat Ahmed A.
Published: March 2022

The study aimed to identify the effectiveness of a behavioral counseling program’s in reducing aggressive behavior among children with mild mental disabilities at the Mu’tah Center for Special Education. The study sample consisted of (10) male and female students with mild mental disabilities, whose ages ranged between (10-14) years. The one group system (the experimental group) was used. The list of aggressive behavior was applied to the study sample in three stages: The first stage was a baseline (pre-test) and lasted a week, and the second stage was a stage after the completion of the application of the guidance program (post-test), where it lasted for six weeks, while the third stage was the (follow-up measurement) phase, which was carried out two months after stopping the implementation of the program, the repetitions of aggressive behavior were counted. The study used the Wilcoxon Matching Pairs Signed test to calculate the differences between the mean of the pre-test scores and the mean of the post/test scores. The study found the following results: There were differences between the study sample members in the two measurements (pre and post) in the relative weight of the study sample and in favor of the post-test, which indicates the effectiveness of the behavioral counseling program. The results also indicate no statistical differences between the study sample members in the two measures (post and follow up), which indicates the continuity of the effectiveness of the behavioral counseling program.
Enterococcal Cervical Discitis Following Transcatheter Aortic Valve Replacement
Authors: Glueck Jesse , Barbera Andrew
Published: March 2022

Prosthetic valve endocarditis (PVE) is a known transcatheter aortic valve replacement (TAVR). Infective endocarditis is associated with a high incidence of embolic events related to bacterial seeding of various sites through hematogenous spread. This seeding can lead to severe morbidity and mortality and requires an increased incidence of clinical suspicion in at-risk patients to diagnose and treat appropriately. We report a case of post cervical discitis in a patient found to have enterococcal bacteremia five weeks post TAVR.
Triquetrum Fracture with Pisiform Dislocation
Authors: Nanduri Arjun , Kim Alison , Nolan Carolyn , Dubey Jesse , Barbera Andrew
Published: March 2022

The authors present a case of a triquetrum fracture and pisiform dislocation diagnosed in the emergency department. The patient described wrist pain with no other complaints. However, after a plain radiograph in the emergency department, a minimally displaced avulsion fracture of the triquetrum and subtle pisiform dislocation was detected. The patient was placed in a forearm volar splint upon consultation with an orthopedist. Careful examination is imperative given the rarity of an associated pisiform dislocation.
Radial neck fracture nonunion: A case report and novel fixation technique
Authors: Kostretzis Lazaros , Zigras Filippos , Bampis Ioannis , Zervakis Nikolaos , Lachanas Ioannis , Ditsios Konstantinos , Boutsiadis Achilleas
Published: March 2022

Non-union of radial neck fractures is a rare entity in adults, and conservative treatment is usually applied. However, when the patient is symptomatic, an optimal functional outcome can only be obtained after operative treatment. There is currently no consensus on the best surgical technique to treat this condition.

We present a 34-year-old male with a radial head non-union and our proposed technique of using a cylindrical bone autograft harvested from the iliac crest and fixation with headless compression screws. At 12 months follow-up, the patient was pain free and had comparable range of motion to the uninjured side.

We recommend a useful technique for the treatment of radial neck fracture nonunion. The preliminary postoperative outcomes show excellent results, while a longer follow-up and a greater number of cases are necessary to confirm the efficacy of this technique.
Adam Mickiewicz and the Concept of the Ethnolinguistic Unity of the Slavs
Authors: Krysowski Olaf
Published: March 2022

Adam Mickiewicz, the Polish romantic poet, perceived language not only as a tool for learning about the history and culture of the Slavs but also as a factor that can restore the unity of these seemingly different and dispersed peoples, who in reality have common roots and who form a single community under ethnic and civilizational considerations. Mickiewicz created the image of the Slavs’ identity in Paris lectures, when Austro-Slavism and southern pan-Slavism were slowly gaining momentum, also in reference to the process of language development and the dynamics of those changes. According to Mickiewicz, language and literature deserved to be called reliable and lasting links that connect the Slavic peoples. By proclaiming such an opinion, not only did he rise above the political divisions, but also he invalidated the sociocultural differences between the Slavs.
Black Women Comics: Sensuality and Intersectionality
Authors: Ebtesam M. El-Shokrofy , Awad Ahmed Asmaa
Published: March 2022

Can sexual jokes and raunchy routines of black women be used to address serious social, religious, and political issues? This article attempts to answer these questions by applying Patricia Collins’s intersectional theory to some selected works by these American actresses and comedians: La Wanda Page, Thea Vidale, Sheryl Underwood, Amanda Seales, Hope Flood, and Simply Marvellous. In an attempt to gain power, self-assertion, and liberty, these comedians employ vulgarity and sexual allusions to openly reveal the three taboos of the society. Being openly performed using the bodies as a way of narrative expression, stand-up comedy allows a mixture of both street culture and pornography to gradually emerge on the surface and open the floor to more black women comedians to join the trend. Using Patricia Collins’s intersectional theory, this article addresses the social, religious, and political issues raised in the selected comedians’ raunchy works and also examines the factors leading to the emergence of this black feminist trend from 1970s to 2000s.
Blake’s Compasses: Materialist Criticism and Romanticism as a Structure of Feeling
Authors: Lee-Six Edward
Published: March 2022

The present article focuses on a potential methodological problem of materialist literary criticism: How can a materialist critique adequately describe and analyze the aspects of a work of art that seem least material—interiority, subjectivity, ambivalence, ineffability, and so on? The central question is whether Raymond Williams’s concept of a “structure of feeling” can adequately bridge this apparent gap between materiality and interiority. The case study used to explore this question is attitudes toward quantification in William Blake. Blake’s work displays contradictory responses to quantification, and, above all, to one of quantification’s symbols: compasses. These contradictory responses, it is argued, are in fact the sublimation of Blake’s ambivalent attitudes to the material conditions that determine his thought and art: nascent industrial capitalism.
Radiant Bodies and Feminist Laboratories: Jean Rhys, Lee Miller, and the Modern Mannequin
Authors: James Emily , Conway Tove
Published: March 2022

The modern mannequin played a singular role in the burgeoning fashion industry of the early twentieth century. Even so, few scholars have sought to recover the mannequin’s voice and story. Working across disciplinary lines, “Radiant Bodies and Feminist Laboratories” pairs Jean Rhys’s fiction with Lee Miller’s photography to chart a feminist path for the mannequin. Each worked as a mannequin in 1920s Paris, and each returned to this formative experience, recasting the mannequin as sentient, watchful, and quietly creative. Each, moreover, imagined her capable of making herself, independent of the demands of designers, employers, and customers. This article argues for the importance of alternative spaces for the feminist imagination—from underground servants’ quarters to cramped, solitary darkrooms—where, unlit and free from the gaze of commerce, the mannequin may reimagine her own form and pursue her own creative desires.
Manfred’s Quest as Limit Test: A Genealogy of Knowledge, Exile, and Gender
Authors: Berger Robert L.
Published: March 2022

This article explores Lord Byron’s Manfred as a contemporary text with the critiques of Michel Foucault, Giorgio Agamben, and Judith Butler. I argue that Manfred’s quest operates as a form of “limit test,” an approach to knowledge that subverts or questions what is taken to be “universal.” This article traces a genealogy of Byron and Foucault’s shared interest in finding a way out for carceral figures who are confined by guilt and “Enlightened” forms of knowledge. Referencing Agamben’s Homo Sacer and the potentiality of being, I suggest Manfred tests the limits of the “truth of being” in its relationship to Power and deconstructs Manfred’s exile from human society. I connect Manfred’s representation of gender and sexuality to Judith Butler’s work in Gender Trouble, wherein she describes homosexuality, bisexuality, and gender mobility as a form of “incest” to society. I invoke Judith Butler’s conception of gender performativity as new way to understand the Manfred/Astarte relationship and link gender with the “truth of being” itself. Read this way, Byron’s work entangles contemporary notions of gender, exile, and knowledge through tropes of incest, sin, love, and resurrection and death, and this positions his work as a confluent site of discourses in biopolitics.
A Study in Furniture: The Moonstone’s “Detective Fever” and Pharmacy of Deduction
Authors: Chatterjee Arup K.
Published: March 2022

This article challenges notions of furniture as being merely figures of speech in Victorian fiction, through what is here demonstrated in an archetypology of furniture based on Wilkie Collins’s novel, The Moonstone (1868). Taking the story beyond its allegory of imperial psychology, I chart the functional aspects of furniture, viewed as archetypes. The Moonstone inspired the interiors of detective plots in the works of Sir Arthur Conan Doyle and Agatha Christie, enabling furniture to transcend its status as dispensable nouns and assume archetypal roles that catalyse and morph the interiors and plots of literary texts. The Moonstone overturned prescriptive and eroticized stereotypes of Victorian parlours, replacing them with male-criminal-and-detective archetypes and the archetypal pharmacy—the prototypical 221B Baker Street quarters. The novel furnished characters’ intimate relationships to objects (glass artifacts, tables and chairs, chests of drawers, and bookshelves), which in turn furnishes the detective plot, at a time when Victorian aesthetics was witnessing a functionalist turn. This in turn shaped the investigative spaces of Holmes and Poirot with tremendous value derived from the new archetypal functions of furniture.
Globally Important Agricultural Heritage Systems (GIAHS) Monitoring and Evaluation Manual: A Technical Reference
Authors: Yiu Evonne , Jang Bosun , Owada Junko , Jeong Myeong-chul , Hwang Daeyong
Published: March 2022

"Globally Important Agricultural Heritage Systems (GIAHS) Monitoring and Evaluation Manual: A Technical Reference" is a research output of the Introduction of Technologies on Characteristic Analysis and Conservation Management in Agricultural Heritage Systems project, a partnership between the Rural Development Administration (RDA) of the Republic of Korea and the United Nations University Institute for the Advanced Study of Sustainability (UNU-IAS). The Manual aims to (1) support the management and governance of GIAHS through specific steps it can take to monitor and evaluate the actions taken for conservation, as defined by the GIAHS Action Plan; and (2) reinforce the importance and usefulness of having an M&E process as an integral part of the GIAHS Action Plan implementation. The Manual opens with an overview of the current state and need for M&E of GIAHS and explains the role played by M&E in a proposed ToC for GIAHS conservation (Chapter 1). It then lays out the purpose and core principles of M&E of GIAHS (Chapter 2), followed by a detailed explanation of the proposed criteria and indicators for monitoring GIAHS (Chapter 3). The Manual maps out a holistic, systematic process to design and implement an M&E process for GIAHS and requisite institutional structures and resources (Chapters 4 and 5). The Manual closes by linking monitoring results and evaluation, focusing on the effective use of findings (Chapter 6).
Investigating law enforcement for coral reef conservation of the Spermonde Archipelago, Indonesia
Authors:   Faculty of Law, Bosowa University, Makassar 90231, South Sulawesi, Indonesia, Renggong Ruslan , Haris Hamid Abd ,   Faculty of Law, Bosowa University, Makassar 90231, South Sulawesi, Indonesia, Yulia Yulia ,   Faculty of Law, Bosowa University, Makassar 90231, South Sulawesi, Indonesia
Published: March 2022

The coral reef ecosystem in the Spermonde Archipelago manifests great potential in ecosystem services. However, it has been degraded to “severely damaged”. In this study we investigated the law enforcement related to coral reef conservation, especially the damage caused by destructive actions. We used mixed qualitative and quantitative methods. We explored existing laws, conductedsemi-structured interviewswith6 informants (five fishermen and one judge), collected data on regional convictions data,and surveyed 48 respondents with a quantitative questionnaire, in 5 sampling sites: South Galesong District, Takalar Regency; KodingarengLompo Island,Sangkarrang District Makassar city, Kapoposang Island; Sarappoand Papandangan Island; PangkajeneandKepulauan Regency. This study detected 26 destructive cases, in which the perpetrators were found guilty by the court with the consideration that their actions damaged the coral reef ecosystem. The perpetrators used bombs, cyanide, and cantrangnets to catch fish and collect corals for trading. The imposed sentence was mild and far from the maximum penalty, both in imprisonment and fine. Notably, none of the perpetrators were sentenced to half of the main legal threats. 96% of (n = 48) respondents in our study area disagreed with the mild penalty. A mild penalty may not provide deterrent effects to the perpetrators or others who have an intention to conduct similar activities.The questionnaire showed that most of the locals know about the conservation area (66%) and its regulation (88%). The best solution to strengthen the conservation effort is to quickly establish a fisheries court in Spermonde Archipelago, which is also supported by locals (92% agreed to the establishment). A fisheries court could examine, adjudicate, and decide fisheries criminal cases, such as illegal fishing and destructive fishing within their jurisdiction. The court could be established by Presidential Decree and it will be under supervision of the Supreme Court of Republic of Indonesia.
Links between bushmeat species occupancy and indigenous hunting: a pilot study from Royal Belum State Park, Peninsula Malaysia
Authors:   Albany Campus, University of Western Australia. PO Box 5771, Albany WA 6332 Australia, Pullella Lauren , Khan Abdul Rashid ,   Department of Public Health Medicine, RCSI & UCD Malaysia Campus, George Town, Malaysia, Pettit Neil ,   Albany Campus, University of Western Australia. PO Box 5771, Albany WA 6332 Australia, Speldewinde Peter Christiaan ,   Albany Campus, University of Western Australia. PO Box 5771, Albany WA 6332 Australia
Published: March 2022

Indigenous communities have been hunting bushmeat species in the tropical forests of South East Asia for over 40,000 years. Today however, many bushmeat species are threatened by unsustainable hunting compounded by the pressures of decreasing forest area and growing human populations. This pilot study aimed to investigate the relationship between the Jahai, an indigenous hunter gatherer tribe and the mammal bushmeat species which they hunt in Royal Belum State Park (RBSP), peninsula Malaysia. A wildlife triggered camera survey was conducted between early May and late June 2018, from which data was used to calculate occupancy predictions for observed Jahai hunters and bushmeat species. Four mammal species occupancy were found to be associated with Jahai hunting pressure, all of which were preferred species among Jahai communities. Species richness of bushmeat species was also found to increase with Jahai occupancy while species diversity index declined, suggesting that Jahai hunting pressure was concentrated on a select few species, even when bushmeat species richness was high. Vegetation cover and the presence of saltlicks were significant drivers of species occupancy. Based on these findings, Jahai hunting pressure should not be disregarded as a threat to bushmeat species in RBSP.