bluuebunny/crossref_metadata_2025 huggingface dataset:
PENERAPAN IPTEK PADA PERENCANAAN ARSITEKTUR - GAMBAR DETAIL MASJID AL MA’UN, BANYUMANIK KOTA SEMARANG
Authors: Suwarto Suwarto , Praharseno Fikri , Buana Lalu Yahya Surya , Lestari Nor Puji , Mawardi Mawardi , Suparman Suparman , Wahjoedi Wahjoedi
Published: October 2023

Kelurahan Pedalangan secara administratif berbatasan dengan Kelurahan Tembalang, Kelurahan Kramas, Kelurahan Padangsari, dan Kelurahan Srondol Wetan. Akibat adanya kawasan pendidikan di Kelurahan Tembalang, maka berdampak pula pada perkembangan wilayah di Kelurahan Pedalangan, baik dari segi perubahan lahan maupun pertumbuhan penduduk. Seiring dengan pertumbuhan penduduk yang pesat di Kelurahan Pedalangan maka harus diimbangi dengan peningkatan fasilitas umum di wilayah tersebut, Untuk memberikan fasilitas umum yang cukup bagi masyarakat di Kelurahan Pedalangan maka diperlukan peningkatan fasilitas ibadah, salah satu fasilitas ibadah yang perlu ditingkatkan khususnya pada wilayah RT/RW 03/03 Kelurahan Pedalangan adalah masjid. Alternatif yang di rencanakan oleh warga sekitar adalah pembangunan masjid baru akan tetapi, yang menjadi kendala adalah kurangnya pengetahuan warga masyarakat tentang peraturan pemerintah untuk mendirikan bangunan dimana lahan yang ada terdapat sumber air/Sendang. Untuk mengatasi hal tersebut, maka dilakukan inventarisasi kondisi lahan dan kebutuhan luas bangunan yang diperlukan.Target yang ingin dicapai dari kegiatan ini adalah memperiapkan Perencanaan Tampak bangunan dan anggaran yang diperlukan agar dapat dipersiapkan dan dicari sumber pendanaan dengan rembug warga masyarakat di Kelurahan Pedalangan khususnya masyarakat sekitar lokasi tentang Pembanguanan Masjid sebagai perkiraan dalam pelaksanaan pembangunan. Metode kegiatan yang direncanakan dimulai dengan diskusi dan musyawarah warga sosialisasi atau penyampaian hasil perhitungan desain struktur dan perencanaan rencana anggaran biaya. Sehingga diharapkan melalui kegiatan ini mampu memberikan manfaat bagi tim pengabdian masyarakat Polines (dosen) maupun bagi masyarakat sekitar.
The Role of Standardization in the Operation of Enterprise Quality Management Systems
Authors: Cao Huihua
Published: October 2023

Standardization serves as the cornerstone of modern enterprise quality management, providing a solid foundation for the operation of quality management systems through the establishment of clear rules and guidelines. This article explores the role of standardization in enterprise quality management systems, with a particular focus on the close relationship between standardization, quality control, efficiency improvement, and market competitiveness. By gaining a deeper understanding of the significance and application of standardization, companies can enhance product quality, optimize resource utilization, and strengthen their competitive edge.
Perfil Epidemiológico e Aspectos Clinicopatológicos dos Pacientes com Câncer de Cabeça e Pescoço em um Centro de Radioterapia do Agreste Pernambucano
Authors: Santos Lucas Renan Alves dos , Silva Marcia Janeide da , Silva Sandy Sterfany Pereira da , Alves José Victor Leal , Santana Breno Washington Joaquim de , Mendes Amanda Caroline Oliveira Henriques , Chaves Rezende Morais Diego , Faria Danielle Lago Bruno de , Mota Cláudia Cristina Brainer de Oliveira
Published: October 2023

Introdução: O câncer de cabeça e pescoço é uma neoplasia maligna com alta prevalência no Brasil e o sexto tipo mais comum no mundo. Objetivo: Evidenciar a prevalência, características sociodemográficas e clinicopatológicas de pacientes com câncer de cabeça e pescoço em um serviço de radioterapia. Método: Estudo transversal retrospectivo dos prontuários de pacientes com câncer de cabeça e pescoço tratados entre janeiro de 2010 e dezembro de 2020 em um centro de radioterapia localizado no Agreste de Pernambuco. Foram coletados os dados clínicos, sociodemográficos e os desfechos clínicos. A análise estatística foi elaborada a partir dos testes qui-quadrado de Pearson, razão de verossimilhança e exato de Fisher, além de ser adotado o nível de significância de 5%. Resultados: Foram obtidos dados de 908 pacientes. O sexo masculino foi o mais prevalente (71,5%), 48,5% dos pacientes tinham entre 50 e 69 de idade, 45,2% não concluíram o 1° grau, 29,3% eram analfabetos e 91% foram atendidos pelo Sistema Único de Saúde (SUS). O diagnóstico de câncer de boca foi o mais frequente (36,5%), sendo a língua o sítio mais acometido (21,1%), e o tipo histológico mais comum foi o carcinoma escamocelular (82%). Houve comprometimento vocal em 14% dos casos, uma pequena parcela realizou traqueostomia (6,6%) e 158 pacientes (17,4%) realizaram tratamento odontológico prévio. Conclusão: Evidenciar o perfil dos pacientes portadores de câncer de cabeça e pescoço possibilita o conhecimento dos grupos vulneráveis para promoção de políticas públicas e ações para melhorar a condição de vida desses indivíduos.
Reform of Labor Wage Determination Provisions: Review of Welfare and Importance in the Job Creation Law
Authors: Chelsea Mutiara Putri  , Hutapea Annisa Khairiyah , Ramadhani Zaky Ihsan Edy
Published: October 2023

The passing of the Job Creation Law by the government is considered to show more partiality to investors or entrepreneurs and marginalizes labor rights, especially in terms of wages, Indonesia's goal to create and guarantee community welfare in accordance with the concept of the Welfare State (Welfare State) adopted becomes blurred.  This article focuses on the discussion related to the first the determination of the minimum wage submitted to the authority of the Governor and by referring to the economic growth of the Regions and inflation conditions of each Region. Second, the Decent Living Needs (KHL) is no longer an indicator of determining the minimum wage for workers. Third, the abolition of sectoral minimum wages previously in the Manpower Law. This article uses the Juridical-Normative research method. This article found that the Economic growth and inflation rate of each region / province vary. Thus the Minimum Wage cannot be equated between people in each region. In an effort to realize equality of position for employers, Law No. 6 of 2023 has denied the state's obligation to protect workers' rights, thus clashing with Article 27 paragraph (2) of the 1945 Constitution. The policy of abolishing the sectoral minimum wage in the Job Creation Law will cause inequality between sectors and cause a sense of injustice for workers.
The Criminalization Of Illicit Enrichment in Combating Corruption in Indonesia
Authors: Dianita  , Pujiyono  , Sutanti Rahmi Dwi
Published: October 2023

Despite Indonesia's ratification of the United Nations Convention against Corruption, 2003 (UNCAC, 2003), there are still some norms that have not been adequately accommodated by national anti-corruption laws, particularly concerning illicit enrichment. This legal study aims to examine the practical implementation of illicit enrichment as a corruption offense in Indonesia and propose the criminalization of illicit enrichment as a future corruption offense. The research methodology employed is normative juridical, which involves analyzing secondary data, with a focus on literature reviews and relevant legislation. The research findings and discussions indicate that the practice of illicit enrichment has been increasingly prevalent, as evidenced by cases involving defendants Bahasyim Assifie and Dhana Widyatmika, who were charged under different articles, namely Article 12 of the Anti-Corruption Law and Article 3 of the Anti-Money Laundering Law, which differ from the essence of illicit enrichment as outlined in UNCAC, 2003. Considering the enforcement practices, it is imperative to criminalize the act of unlawful enrichment or illicit enrichment through the revision of the Anti-Corruption Law or the Criminal Code.
ЗАЛЕЖНІСТЬ ПРОДУКТИВНОСТІ ПОРОСЯТ НА ДОРОЩУВАННІ ВІД ЗГОДОВУВАННЯ ФІТОБІОТИКУ «SANGROVIT EXTRA»
Authors: Волошинов Василь Вікторович , Повод Микола Григорович , Лихач Вадим Ярославович , Лихач Анна Василівна , Нечмілов Віктор Миколайович
Published: October 2023

В практиці сучасного тваринництва шляхом оптимізації технології виробництва продукції свинарства приділяється особлива увага впровадженню інтенсивних технологічних рішень задля підвищення продуктивності свиней за рахунок нових кормових добавок органічного походження. В науковій роботі вивчався вплив на продуктивність молодняку свиней в період дорощування кормової добавки – фітобіотику Sangrovit Extra. Матеріалом для дослідження був гібридний молодняк свиней, отриманий за поєднання двохпородних свиноматок (ВБ×Л) з кнурами синтетичної лінії РІС-337 генетичної компанії РІС. Об’єктом дослідження були процеси годівлі, ріст і витрати корму та ефективність дорощування поросят за згодовування їм фітобіотику Sangrovit Extra. Дослідження проведені в цеху дорощування ТОВ «НВП «Глобинський свинокомплекс» Кременчуцького району Полтавської області. Для проведення досліджень в лютому 2023 року було відібрано по 2650 голів поросят. Молодняк був розділений на контрольну групу (І група) – вирощування за базовою технологією (БТ) і згодовували основний раціон (ОР) та дослідну групу (ІІ група): БТ(ОР) + продукт Sangrovit Extra з розрахунку 100 г на 1 тону готового комбікорму. Представлені результати науково-господарського досліду свідчать, що використання фітобіотику Sangrovit Extra не мало істотного позитивного впливу на інтенсивність росту та збереженість поросят під час їх дорощування. Тварини контрольної групи (БТ) мали вищу енергію росту в період стабільного споживання кормів і зменшували її під час зміни рецептів раціону. Встановлено, що поросята ІІ групи спожили менше на 13,57% першого престартерного корму та більше на 6,72% дешевшого другого престартерного корму, це дещо знизило собівартість одного поросяти. Використання препарату Sangrovit Extra спричинило зниження інтенсивності росту поросят на 4,08% і, як результат, меншу на 2,99% їх масу по завершенню дорощування. Використання препарату покращило на 1,14% конверсію корму і зменшило на 4,36% його вартість в розрахунку на одну голову, та на 8,32% в розрахунку на 1 кг приросту, що посприяло зменшенню на 3,6% собівартості дорощування. Констатуємо, що використання Sangrovit Extra сприяє повільному біологічному ефекту фітобіотиків щодо підвищення росту та продуктивності тварин у зазначені періоди вирощування, який не супроводжується різкими змінами гомеостазу та побічними ефектами, а за постійного використання вірогідно збільшить вплив на ефективність вирощування.
СУЧАСНА ГЕНЕАЛОГІЧНА СТРУКТУРА ЛЕБЕДИНСЬКОЇ ПОРОДИ ТА ШЛЯХИ ЇЇ ЗБЕРЕЖЕННЯ
Authors: Ладика Володимир Іванович , Скляренко Юрій Іванович , Павленко Юлія Миколаївна , Вечорка Вікторія Вікторівна , Чернявська Тетяна Олексіївна , Малікова Альона Іванівна , Кучкова Тетяна Павлівна
Published: October 2023

У статті наведені результати досліджень щодо особливостей формування генеалогічної структури лебединської породи. Проведений історичний пошук щодо створення окремих генеалогічних ліній, а також встановлений взаємозв’язок між ними. Встановлено, що формування генеалогічної структури бурої худоби Північного сходу України розпочалося наприкінці XVIII початку XIX століття. Для цього, з метою покращення місцевої худоби, регулярно завозилися плідники швіцької породи та різних її відрідь, головним чином з–за кордону. У результаті тривалої роботи було сформовано більше двадцяти ліній лебединської породи. Вони походили головним чином від дев’яти плідників закордонної селекції (або нащадків плідників, завезених з-за кордону). Певні лінії було отримано в результаті використання кросів ліній, а також з використанням плідників джерсейської породи. Матеріалом для дослідження були Державні книги племінних тварин лебединської та швіцької порід великої рогатої худоби восьми томів. Для характеристики бугаїв використовували відомості про походження, молочну продуктивність корів-матерів і належність до лінії. Сучасний стан генеалогічної структури маточного поголів’я оцінювали за даними бонітування племінної худоби в племінних господарствах Сумської області. Генеалогічну структуру плідників, сім´я яких зберігається в глибокозамороженому стані визначали за використання Каталогу бугаїв молочних і молочно-м’ясних порід для відтворення маточного поголів’я у 2023 році. Встановлено, що більшість тварин походять від ліній швіцької породи як Північно-Американської, так і Західно-Європейської селекцій. В господарствах області маточне поголів’я лебединської породи віднесені до двох лебединських ліній: Чуткого та Бравого. Наявний запас сім´я плідників лебединської породи та їх помісей зі швіцькою породою дев’яти ліній (Бравого 1510, Чуткого 4281, Балкона 1799, Макета 4307, Лака 964, Мінуса 370, Хілла 107915, Сюпріма 124652, Елеганта 148551)дає змогу проводити роботу зі збереження лебединської породи. Організація замовних парувань дозволяє уникнути небажаного інбридингу. Подібна робота повинна проводитися під контролем науковців. У господарствах області проводяться заходи з розширення генеалогічної структури даної популяції за рахунок використання бугаїв оригінальної бурої німецької породи. Нащадки цих плідників використовуються у галузі відтворення на маточному поголів’ї лебединської породи в Сумській області.
Improving the Logistics of Institutional Postal Services
Authors: Nagy Pálma Eszter , Bányai Tamás
Published: October 2023

Postal services are often considered by the different institutions as a back-up service. Taking into account that in case of large geographical coverage these services can generate significant costs, it is important to optimize the postal service functions within these institutions and to develop the already existing conventional postal services. Within the frame of this article the authors review the logistics processes of the postal services at the University of Miskolc to propose improvements to the processes of postal services focusing on delivery. The main regulatory elements and the logistics processes of the institutional postal services are discussed and some critical remarks are described focusing on three main areas: the facility location optimization of the institutional postal services, the lack of use of modern technologies and the lack of modern administrative facilities. On the basis of these criticisms, the authors define recommendations for improving institutional postal services. Regarding the facility location optimization problem, a mathematical model and an optimization algorithm is described to evaluate the efficiency of the logistics processes of delivery services. The proposed methodology supports a cost-based analysis of different solution variants and a priority-based differentiation between institutions and offices. The suggested approach is tested with a real scenario, where the numerical results validate the efficiency of the evaluation of optimization algorithm. The second improvement direction is the application of a pneumatic tube system. The authors show the most important parts of the proposed pneumatic tube system, which can lead to decreased labor cost and increased service level.
Supply chain models for non-reusable packaging logistics
Authors: Bányai Tamás
Published: October 2023

Packaging logistics plays an important role in today’s economy, because a well-chosen packaging can significantly increase the market share of a company. However, packaging has advantageous impacts on the purchasing, production and distribution processes, but negative impact must be also taken into consideration focusing on sustainability, costs, environmental impacts and logistics. Within the frame of this article, the author suggests a potential model structure for non-reusable packaging logistics focusing on the type of the collection and distribution routes, number of senders and receivers, location of recycling or disposal, maintenance and cleaning location, existence of agents, logistics centers and central depots. The suggested approach makes it possible to derive the typical supply chain models for both non-reusable and reusable packaging. Within the frame of this article, the most important supply chain models for non-reusable packaging logistics are described.
Optimizing Radiation Dose Using Ctdi Value Analysis and Image Quality in the Thorax Low Dose CT Scan (LDCT) Technique with Reduced Dose Variations Using Idose Software
Authors: Adeline Nova , Anwar M. Choiroel , Kartikasari Yeti , Foresta Laila Rose
Published: October 2023

Radiation exposure to patients with higher cumulative effective doses on thorax CT scanning is very detrimental for cancer patients undergoing follow-up and raises the level of concern about the harmful effects of radiation doses received by patients. Reducing the tube voltage will reduce the radiation dose and image quality. To maintain good image quality, the iDose strength level is set. iDose is able to reduce radiation dose and improve image quality by maintaining low noise. Analyze the optimization of radiation dose and image quality in the thorax Low Dose CT Scan (LDCT) examination protocol with tube voltage settings and variations in the use of iDose software. This type of research is True-Experimental research with a Posttest-Only Control Design. The object used is a water phantom with tube voltage settings of 80 kVp, 100 kVp and 120 kVp and the use of iDoe 3 -5. Assessment includes radiation dose, noise, SNR and NPS. After getting optimal results from setting the tube voltage and iDose strength level, these results were applied to a Thorax CT Scan examination in patients, and a subjective assessment of image quality was carried out. Reducing the tube voltage (kVp) from 120 kV to 80 kV was able to reduce the radiation dose by 69.8%, and reducing the tube voltage from 120 kV to 100 kV in the Thorax CT Scan protocol was able to reduce the radiation dose by 34.2 %. There is an influence of setting the tube voltage and setting the iDose strength level on the radiation dose and image quality of the Low Dose CT Scan of the Thorax. Setting tube voltage and high iDose strength levels can improve image quality in CT scans, characterized by decreasing noise and NPS values and increasing SNR values. Tube voltage settings and iDose level settings affect the radiation dose and image quality. The use of a tube voltage of 80 kVp and strength level iDose 5 is able to provide optimal radiation dose and image quality on Thorax Low Dose CT Scan.
Longitudinal Patterns of HBA1c Trajectories in Patients with Type 1 Diabetes
Authors: Chowdhury Biswajit , Versloot Judith , Minotti Simona C.
Published: October 2023

Introduction: Type 1 diabetes is a chronic condition that affects adolescents’ quality of life and raises the risk of developing mental health concerns and diabetes-related complications. Measuring glycated hemoglobin (HbA1c) over time is the standard of care within the management of type 1 diabetes; however, the determinants of different HbA1c trajectories remain poorly understood. In the secondary analysis of the data collected for the Integrated Care Model (1), we aimed to identify groups of HbA1c trajectories with similar trends and examine the association between these groups and demographic and psychosocial variables.
Methods: HbA1c data were collected at 4 consecutive time points with a gap of 3±1 months. We used Leffondré’s method (2) and Group-based trajectory modeling (GBTM) (3) to derive the groups of HbA1c trajectories among 91 adolescents. Baseline characteristics of the adolescents included in the groups were analyzed by univariate analysis.
Results: Leffondré’s method identified three groups of trajectories: stable (63%), decreasing (17%), and increasing (20%). The baseline HbA1c levels for the three groups were 8.00±0.93, 10.07±1.63, and 8.21±1.14, respectively. Among the baseline characteristics, only the treatment method distinguished the groups of adolescents with similar trajectories of HbA1c over time (p=0.015). The GBTM method identified similar groups: stable (67%), decreasing (18%) and increasing (15%). The baseline HbA1c levels for the three groups were 7.89±0.88, 9.81±1.61, and 9.00±1.38, respectively. Groups produced by GBTM were also distinguished by treatment modality at baseline (p=0.022).
Discussion: We identified three distinct patterns of HbA1c trajectories in adolescents. The only baseline characteristic that significantly distinguished these trajectories was the treatment modality.

References

J. Versloot, et al., An Integrated Care Model to Support Adolescents With Diabetes-related Quality-of-life Concerns: An Intervention Study. Can J Diabetes (2022).

K. Leffondré, et al., Statistical measures were proposed for identifying longitudinal patterns of change in quantitative health indicators. J Clin Epidemiol 57, 1049–1062 (2004).

D. S. Nagin, Group-based trajectory modeling: an overview. Ann Nutr Metab 65, 205–210 (2014).
Development and Validation of a Risk Prediction Model for 5-year Risk of Hypertension in Women of Reproductive Age
Authors: Stefan George E. , Filion Kristian B. , Platt Robert W. , Hutcheon Jennifer A. , Smith Graeme N. , Heath Anna , Grandi Sonia M.
Published: October 2023

Introduction: The rate of pregnancy complications has been steadily increasing over the past decade. These complications include hypertensive disorders during pregnancy (HDP), gestational diabetes, and preterm birth. Previous studies have shown an association between pregnancy complications and the development of cardiovascular disease (CVD). Hypertension has been established as a precursor to CVD, implying that predicting the incidence of hypertension could help reduce the overall prevalence of CVD. The objective of this study is to provide clinicians with a validated tool to identify women in the post-partum period with increased risk of hypertension.
Methods: A risk prediction model was developed to estimate the 5-year risk of incident hypertension among nulliparous women, accounting for obstetrical history and complications of pregnancy. Variables with low prevalence (<1%) were excluded and lasso-regularized Cox regression was used to further exclude variables with negligible effects on the predictions. A baseline analysis was conducted using an extended Cox model. A proportional hazards assumption violation for HDP was dealt with by allowing the associated risk to vary over time. Harrell's concordance (C)-index was used to measure discrimination ability and internal validation was performed using bootstrap resampling (n=500 replicates).
Results: Eleven variables were included in the final model, with an HDP diagnosis having the largest estimated effect on the risk of hypertension. The predicted 5-year probability of hypertension diagnosis for a subject with median attributes was 7% (95% CI: 6.5%, 7.5%).
Discussion: HDP alongside other risk factors can provide insight into identifying women in the post-partum period who would benefit from the early initiation of cardiovascular prevention strategies and treatment.
Hepatitis B Screening Program for patients attending out-patient department (OPD) at Sir Salimullah Medical College Mitford Hospital, Dhaka – An Observational Study
Authors: Md Rashid Un Nabi Quazi , Karim Md Fazal , Podder Provat Kumar , Islam Mohammad Nasirul , Hossain Mohammad Shawkat , Bepari Md Shahin , Gazi Mohammad Ashraf Hossain
Published: October 2023

Background: Hepatitis B (HBV) is a major cause of chronic hepatitis, cirrhosis of liver and hepatocellular carcinoma in Bangladesh. It is also the most common cause of death from liver disease in the country. The prevalence of hepatitis B is 5-6% in the general population. So the present status of the virus is considered as an important public health concern of Bangladesh.
Objectives: To investigate hepatitis B prevalence among the persons attending the OPD and to increase awareness about hepatitis B. Materials and methods: A cross-sectional observational study was carried out the at the Department of Hepatology, Sir Salimullah Medical College Mitford Hospital, Dhaka on March 17&18, 2022 at Special Treatment Campaign on the occasion of celebration of the birth anniversary of the Father of Nation, Bangabandhu Sheikh Mujibur Rahman. A total of 190 people of both sexes from 18 years to 50 years of age group were enrolled in the study. These people were unaware of whether they were carrying hepatitis B virus or also was not aware of whether they are suffering from any kind of liver disease. Informed consent was taken and a pre-designed structured questionnaire was used. Screening was done by HBsAg detection using rapid diagnostic kit.
Result: The mean age of respondents was 35.95±6.42 years with a male to female ratio of 0.83. Most of the respondents were married (72.63%) and Muslim (87.37%). Among them 47.36% of the respondents were service holders. Only 17.89% had a previous history of some types of hepatitis. 25.26% of respondents had history of different types of surgical procedure. 8 (4.2%) participants were found positive for HBsAg on the screening test in our study.
Conclusion: This study shows 4.2 % of participants were screening positive among the respondents. This correlate with the intermediate prevalence of hepatitis B in Bangladesh as stated in World Health Organization data. Screening program increases knowledge and awareness among the population and thereby increase treatment seeking, which ultimately reduce incidence of disease and complications as well as death.
Sir Salimullah Med Coll J 2023; 31: 3-8
The Efficacy of Appendicitis Inflammatory Response Score in Diagnosis of Acute Appendicitis
Authors: Hossain Kazi Ismail , Pervin Shahana , Rashid Md Shoeb Ur , Chhanda Chhamita Sultana , Rahman Mohammad Masudur , Sumon Ruhul Amin , Kar Mousumi , Ahmed Faysal , Tabassum Maliha , Jahan Ishrat
Published: October 2023

Background: Acute appendicitis is one of the most common cause of acute abdominal pain. The management of suspected appendicitis represents a prime target for improved decision-making in emergency surgical care (OPD, Emergency room). The aim of the work is to evaluate the appendicitis inflammatory response (AIR) score and compare its performance in predicting the risk of appendicitis to the Alvarado score.
Objective: To evaluate the diagnostic performance of the AIR score and potential benefits of risk stratification to guide clinical decision making.
Methods: This prospective observational study was conducted in the OPD and Emergency department, Sir Salimullah Medical College & Mitford Hospital, Dhaka. From June’2021 to May’2022. A total 240 patients with right lower abdominal pain. History, clinical examination, hematological, radiological investigations were done. AIR score was calculated. Considering histopathology report as gold standard the score was compared. Histopathology report was done in Pathology Department of SSMC, Dhaka.
Results: Right iliac fossa pain (100%) was the most common symptom, followed by vomiting (58.3%), temperature (29.5%), and rebound tenderness. After applying AIR scorings, 44(18.3%) patients in low-risk group (0-4), 112(46.7%) patients in the intermediate risk group (5-8) and 84(35.0%) patients in the high-risk category (9-12). Amongst the 240 applying the AIR score, Sensitivity of inflammatory response score vs histopathology findings was 97.9%, specificity 78.4%, accuracy 93.8%, positive and negative predictive values were 94.4% and 90.9% respectively.
Conclusion: Risk stratification of patients with suspected appendicitis by the AIR score could guide decision-making to reduce admissions, length of hospital stay, cost and case fatality rate, optimize utility of diagnostic imaging and to decrease negative exploration.
Sir Salimullah Med Coll J 2023; 31: 47-52
Role of Oxygenation in Moderate COVID-19 Pneumonia with High Flow Nasal Cannula and Standard Non-Rebreathing Mask: A Comparative Study
Authors: Mazumder Prosanjit , Banik Chandan Kumar , Basak Ajit Kumar , Saifuddin AZM , Habibullah AKM , Ghosh Goutam Chandra
Published: October 2023

Background: To evaluate the effectiveness of High Flow Nasal Cannula (HFNC) and standard non rebreathing mask (NRBM) as oxygen delivery device, in moderate cases of COVID-19 Pneumonia.
Methods: A single-centre, prospective analysis conducted at KBFGH. Eighty enrolled patients were randomly divided into two groups according to the oxygen delivery device used. Group 1 (n = 40) received HFNC and group 2 (n = 40) received NRBM as initial oxygen delivery device, to maintain a target saturation of e” 96% in both groups. The success rate of oxygen therapy, time to progression to severe disease, PaO2, PaO2/FiO2 ratio, respiratory rate, heart rate, blood pressure, number of patients requiring NIV or endotracheal intubation, time for de-escalation of oxygen therapy to lower Fio2 device and patient satisfaction level were compared among the two groups.
Results: Demographic, clinical variables and treatment given were comparable in the two groups. In the HFNC group 83.3% patients had successful outcomes with the initial oxygen therapy device used as compared to 66.6% in the NRBM group. However, the use of HFNC resulted in improved oxygenation (P < 0.001), better patient satisfaction (P < 0.001) and shorter time for de-escalation of oxygen therapy to a lower FIO2 device (3.75 ± 1.032 vs. 6.83 ± 0.928).
Conclusions: HFNC is a reliable oxygen therapy modality for moderate category COVID- 19 pneumonia that results in better oxygenation and a greater patient satisfaction level as compared to a non-rebreathing mask.
Sir Salimullah Med Coll J 2023; 31: 79-85
INSTITUTIONAL POLICIES ON ARTIFICIAL INTELLIGENCE IN UNIVERSITY LEARNING, TEACHING AND RESEARCH
Authors: Spivakovsky Oleksandr V. , Omelchuk Serhii A. , Kobets Vitaliy V. , Valko Nataliia V. , Malchykova Daria S.
Published: October 2023

Generative artificial intelligence is rapidly transforming the educational process and the scientific work of students, lecturers, researchers and administrators of higher education institutions. There are limited and contradictory recommendations for the use of artificial intelligence in the educational process and in the educational programmes of higher education institutions. To define the scope of AI application, there is a need to develop institutional policies for higher education institutions, which will allow the academic community to determine the appropriate scope of AI application in the educational process and prevent the use of AI in areas where ethical norms are violated. The purpose of the article is to summarise and systematise the experience of forming institutional policies for the application of artificial intelligence in education, training and research in higher education institutions using the experience of Kherson State University.
The article presents the developed institutional policies for students, lecturers and researchers with recommended and not recommended initiatives for the use of AI in the educational process and research at Kherson State University. The purpose of these institutional policies was to create an inclusive environment of modern digital tools for involving of lecturers of non-professional specialties and define the framework for the use of artificial intelligence in education, teaching, and research of all subjects (participants) of educational activity. The recommendations are aimed at empowering all participants to select educational components creatively and at improving the efficiency of the educational process and research activities through the use of AI tools.
Issues requiring further research regarding generative platforms lie in three thematic areas: knowledge base; transparency and ethics; digital transformation of organizations and societies. It is also relevant to create an educational environment that encourages the interaction and dissemination of positive practice of digital transformation of all participants of the educational process.
Beyond greenhouse gases - a natural capital-based sustainability assessment framework for the waste-to-energy approach
Authors: Lam Chor-man , Keung Anthony Man-yin
Published: October 2023

Although greenhouse gas (GHG) emissions and marine plastic reduction have been recognised as essential factors for the sustainability performance of waste-to-energy (WTE) facilities, there is a lack of comprehensive evaluation tool for quantifying the environmental, social and economic impacts caused by WTE projects. To fill the gap, this study developed a natural capital-based sustainability assessment (NCSA) framework for evaluating the sustainability of WTE projects. The merits of the NCSA framework include (1) the quantification of the benefits caused by the avoidance of marine plastic pollution by WTE projects, and (2) an inclusive sustainability evaluation framework that holistically assesses the environmental, social and economic performance associated with GHG and marine plastic reduction. The NCSA framework has been demonstrated in the case study on the Sanya WTE Project. The results showed that the Sanya WTE Project emitted 265,376 tonnes of CO2e of GHG and prevented 28,242 - 75,312 tonnes of marine plastic during the study period, which is equivalent to a net benefit of CNY41.90 million - 464.45 million. The case study demonstrated that the NCSA framework is a comprehensive evaluation tool that provides clear and sound results for guiding decisions towards sustainable waste management and the overall sustainability of cities.
YENİLENMİŞ CİHAZLAR İÇİN ENDÜSTRİ 4.0 STANDARTLARI
Authors: TUNCER Özge , ALAEDDİNOĞLU Muhammed Fatih
Published: October 2023

Teknolojinin gelişmesiyle birlikte internet hayatımızın pek çok alanında önemli bir rol oynamaya başlamıştır. Endüstri sektöründe ileri teknolojinin etkisini artırmak, üretimdeki hataları azaltmak, rekabetçi üretime ayak uydurmak, üretim sürelerini azaltmak, kaynakları daha verimli kullanmak, süreçleri otonom hale getirmek ve nesnelerin internetini (IoT) üretime dahil etmek amacıyla Endüstri 4.0 kavramı ortaya çıkmıştır. Bu durum, endüstrideki üretimin daha verimli bir şekilde gerçekleşmesi anlamını taşımaktadır. Ancak teknolojinin gelişmesi aynı zamanda elektronik cihaz israfını (e-atık) da beraberinde getirmektedir. Eski cihazlar geri dönüşüm ve onarım yoluyla yenilenebilmekte ve bu sayede cihazların kullanım ömürleri uzatılabilmektedir. Yenilenmiş cihazların üretiminde ve bakımında Endüstri 4.0 teknolojilerinin kullanılması, üretim sürecinin verimliliğini artırabilmekte ve maliyetleri azaltabilmektedir. Dolayısıyla bu alanda Endüstri 4.0’ı kullanmak sektörde rekabet edebilme açısından önem arz etmektedir. Ayrıca yenilenmiş cihazların kullanımının artması çevresel sürdürülebilirliği de katkı sunmaktadır. Bu çalışmada Endüstri 4.0'ın ortaya çıkışı ve tanımı, nesnelerin interneti ile bağlantısı, yenilenmiş cihaz tanımı, Endüstri 4.0 ile üretim ve iletişim standartları üzerinde durulmaktadır. Sonuç olarak standartların daha net anlaşılması için yenilenmiş bir akıllı cihazın yenilenme aşamaları ve izlenmesi gereken üretim ve iletişim standartları örnek olarak anlatılmaktadır.
Rol Yapma Oyunlarında (RYO) Sanal Karakter Davranışlarını Yönlendirmede Davranış Ağaçlarının (DA) Rolünün ve Etkisinin Analizi
Authors: ÖZBEK Ebru , AYDIN Hakan , BAL Yüksel , GÜNEY Zafer
Published: October 2023

Rol yapma oyunları (RYO), bir bilgisayar oyununda sanal bir karakterin kontrol edilmesine dayanan bir oyun türüdür. Günümüzün dinamik oyun dünyasında, oyuncuların karakterlerin gelişimini şekillendirmesi, hikâyenin seyrini etkilemesi ve oyun evrenindeki kararları belirlemesi gibi unsurlar, RYO türünün temel özelliklerini oluşturur. Davranış ağacı (DA), bilgisayar oyunları gibi uygulamalarda karakterlerin veya nesnelerin davranışlarını yönlendirmek için kullanılan hiyerarşik ve yapılandırılmış bir programlama modelidir. Bu çalışmada, Sanal Gerçeklik (SG) ortamında RYO türünde DA'ların kullanımının sanal karakter gelişimindeki, hikâye ilerlemesindeki ve oyuncu kararlarının yönlendirilmesindeki rolünün ve etkisinin analiz edilmesi amaçlanmıştır. Çalışmanın temel motivasyonu, DA’ların RYO oyunlarında kullanımının, oyuncu deneyimini dinamik olarak şekillendirerek zenginleştireceği oluşturmaktadır. Bu motivasyon DA modelinin diğer oyun türlerinde olduğu gibi RYO türünde de oyuncuların karakterlerin davranışlarını etkileyerek daha kişisel bir deneyim yaşamalarını ve oyun deneyimini artırmalarını sağlayabileceğine dayanmaktadır. Bu bağlamda çalışmamızda UNITY 3D ortamında geliştirilen bir RYO oyunu üzerinde (VR-RPG-GAME) gerçekleştirilen deneylerle test edilmiş ve deneylerden elde edilen veriler analiz edilmiştir. Söz konusu deneylerde, oyuncuların karakterlerin karar verme yetenekleri, hikâye ilerlemesi, düşman etkileşimi ve karakter gelişimi üzerindeki etkilerinin analiz edilmesi amaçlanmıştır. Çalışmada DA'ların RYO oyun deneyimi üzerindeki gerçek etkisini anlamak için sistematik bir yaklaşım benimsenmiştir. VR-RPG-GAME’in geliştirilmesinde C# programlama dili, DA kütüphaneleri ve eklentileri, SG teknolojisi, UNITY Asset Store ve grafik tasarım araçları kullanılmıştır. Bu çalışmanın özellikle RYO türünün kullanıcılar tarafından DA tabanlı olarak geliştirilmesi açısından bilgisayar oyun teknolojisi çalışma alanına katkı sağlayacağı değerlendirilmektedir.
EVALUASI KINERJA PELABUHAN NAMBO WILKER LAWELE SEBAGAI SIMPUL UTAMA DISTRIBUSI ASPAL BUTON
Authors: Aldinoman Aldinoman , Kadir Abdul , Putra Adris Adi
Published: October 2023

Penelitian ini bertujuan mengevaluasi kinerja Eksisiting Pelabuhan nambo/lawele dan menyusun strategi pengembangan Pelabuhan Nambo sebagai simpul utama pendistribusian aspal buton. Metode penelitian dilakukan dengan mengevaluasi data kondisi ekisting Pelabuhan (kondisi topografi, kondisi hidrometri, hidroecanografi), kemudian melakukan analisis kinerja Pelayanan Pelabuhan sesuai dengan Keputusan Dirjen Perhubungan Laut Nomor : UM.002/38/18/DJPL-11 tanggal 15 Desember 2011 dan Peraturan Dirjen Hubla No. HK103/2/2/DJPL/-17 tentang Pedoman Perhitungan Kinerja Pelayanan Operasional Pelabuhan yang match dengan data produktivitas selama 5 (lima) tahun terakhir dan proyeksi produktivitas 20 tahun kedepan. Kemudian perumusan strategi dilakukan dengan analisis SWOT. Dari hasil penelitian diperoleh kinerja eksisting pelayanan Pelabuhan Nambo dengan indikator waktu pelayanan tambat, pelayanan bongkat-muat di dermaga, dan utilisasi fasilitas Pelabuhan dalam kategori baik dan memenuhi standar kinerja yang ditetapkan oleh Kementerian Perhubungan. Namun dari hasil proyeksi produktivitas 20 (dua puluh) tahun ke depan, kinerja fasilitas eksisting dalam kategori kurang baik. Dari hasil analisis SWOT diperoleh Pelabuhan nambo berada di kuadran I berarti pelabuhan mempunyai peluang dan kekuatan dan strategi pengembangan yang dilakukan adalah mendukung kebijakan pertumbuhan yang agresif atau growth oriented strategy dengan memanfaatkan peluang yang ada serta kekuatan internal yang dimiliki mencoba meminimalisir kelemahan, menggunakan tingkat kekuatan sebagai modal utama, serta menekan kelemahan yang akan berpotensi akan mengurangi kekuatan dan menghilangkan ancaman yang ada.

Kata Kunci : Pelabuhan, Kinerja, Strategi
Computation of Algebraic Expressions and Geometric Series with Radicals
Authors: Annamalai Chinnaraji
Published: October 2023

Computational science is a rapidly growing interdisciplinary area where science, computation, mathematics, and its collaboration use advanced computing capabilities for understanding and solving the most complex real-life problems. Also, the growing complexity of mathematical and computational modelling demands the simplicity of mathematical equations for solving today’s scientific problems and challenges. For this purpose, algebraic expressions and geometric series of radicals are introduced in this article.
Biomimetic electrospun nanofibrous scaffold for tissue engineering: preparation, optimization by design of experiments (DOE), in-vitro and in-vivo characterization
Authors: Anjum Shabnam , Li Ting , Arya Dilip Kumar , Ali Daoud , Alarifi Saud , Yulin Wang , Hengtong Zhang , Rajinikanth P. S. , Ao Qiang
Published: October 2023

Electrospinning is a versatile method for fabrication of précised nanofibrous materials for various biomedical application including tissue engineering and drug delivery. This research is aimed to fabricate the PVP/PVA nanofiber scaffold by novel electrospinning technique and to investigate the impact of process parameters (flow rate, voltage and distance) and polymer concentration/solvent combinations influence on properties of electrospun nanofibers. The in-vitro and in-vivo degradation studies were performed to evaluate the potential of electrospun PVP/PVA as a tissue engineering scaffold. The solvents used for electrospinning of PVP/PVA nanofibers were ethanol and 90% acetic acid, optimized with central composite design via Design Expert software. NF-2 and NF-35 were selected as optimised nanofiber formulation in acetic acid and ethanol, and their characterization showed diameter of 150–400 nm, tensile strength of 18.3 and 13.1 MPa, respectively. XRD data revealed the amorphous nature, and exhibited hydrophilicity (contact angles: 67.89° and 58.31° for NF-2 and NF-35). Swelling and in-vitro degradability studies displayed extended water retention as well as delayed degradation. FTIR analysis confirmed solvent-independent interactions. Additionally, hemolysis and in-vitro cytotoxicity studies revealed the non-toxic nature of fabricated scaffolds on RBCs and L929 fibroblast cells. Subcutaneous rat implantation assessed tissue response, month-long biodegradation, and biocompatibility through histological analysis of surrounding tissue. Due to its excellent biocompatibility, this porous PVP/PVA nanofiber has great potential for biomedical applications.
Mechanobiology in oncology: basic concepts and clinical prospects
Authors: Chen Michelle B. , Javanmardi Yousef , Shahreza Somayeh , Serwinski Bianca , Aref Amir , Djordjevic Boris , Moeendarbary Emad
Published: October 2023

The interplay between genetic transformations, biochemical communications, and physical interactions is crucial in cancer progression. Metastasis, a leading cause of cancer-related deaths, involves a series of steps, including invasion, intravasation, circulation survival, and extravasation. Mechanical alterations, such as changes in stiffness and morphology, play a significant role in all stages of cancer initiation and dissemination. Accordingly, a better understanding of cancer mechanobiology can help in the development of novel therapeutic strategies. Targeting the physical properties of tumours and their microenvironment presents opportunities for intervention. Advancements in imaging techniques and lab-on-a-chip systems enable personalized investigations of tumor biomechanics and drug screening. Investigation of the interplay between genetic, biochemical, and mechanical factors, which is of crucial importance in cancer progression, offers insights for personalized medicine and innovative treatment strategies.
A case report of left ventricular lead implantation via total three-dimensional transseptal puncture after tricuspid valve replacement
Authors: Gao Jia , Zhang Nan , Zhang Binghang , Sun Meng , Meng Zhijun , Guo Min , Wang Rui
Published: October 2023

Background

Ventricular lead implantation is relatively difficult for patients with bradyarrhythmia after tricuspid valve replacement. Right atrial (RA) abnormalities often occurred in patients with tricuspid valve disease; conventional coronary sinus (CS) lead implantation is not easy to operate. Therefore, it is necessary to develop a safe method for implanting LV endocardial leads in patients after tricuspid valve replacement.

Case presentation

A 76-year-old Asian woman who had been implanted with a metal tricuspid valve replacement 4 years ago was admitted to the Department of Cardiology for pacemaker implantation due to transient blackout related to persistent atrial fibrillation with long pauses. The patient's family rejected the surgical placement of an epicardial LV lead. Therefore, we first intended to operate LV lead implantation through the CS; however, the orifice of the CS was virtually difficult to seek. Ultimately, we utilized total 3-dimensional (T3D) transseptal puncture (TSP) under the guidance of the CARTO 3 system; thus, we implanted the LV endocardial lead, which contributed to the accurate puncture of the central fossa ovalis and ensured the safety of TSP in the case of RA enlargement. Meanwhile, the CARTO 3 system contributed to the localization of the LV lead to the LV free wall during implantation. All the intraoperative and postoperative pacemaker parameters were favorable; no intraoperative or postoperative complications occurred.

Conclusions

This case report may provide a novel surgical approach for LV lead implantation in patients who underwent tricuspid valve replacement or patients who may benefit from cardiac resynchronization therapy but failed to implant CS lead.
Echoes of the past: niche evolution, range dynamics, and their coupling shape the distribution of species in the Chrysanthemum zawadskii species complex
Authors: Lu Wen-Xun , Wang Zi-Zhao , Hu Xue-Ying , Rao Guang-Yuan
Published: October 2023

The distribution of species changes over time, and the current distribution of different species could result from distinct eco-evolutionary processes. Thus, investigating the spatiotemporal changes in the niche and geographic range of species is fundamental to understanding those processes and mechanisms shaping the current distributions of species. However, many studies only compared the current distribution and niche of the target species, ignoring the fact that the range shift of species is a dynamic process. Here, we reconstructed niche evolution and range dynamics of species to provide more information on related eco-evolutionary processes. We focused on a monophyletic species complex,Chrysanthemum zawadskiispecies complex, in which species occupy diverse habitats and exhibit different distribution patterns. Specifically, we investigated the niche breadth and overlap between lineages or species of the complex in geographic and environmental spaces. We then tested the phylogenetic signals for different climatic variables and estimated the niche of ancestral nodes on a time-calibrated phylogeny. Next, we used phyloclimatic modeling to reconstruct the dynamics of range shift for this complex. Our results show that this complex contains both specialist and generalist species, and niche diverges greatly among different species and intraspecific lineages of the complex. The moisture gradient may be the primary driver of the niche divergence of species in the complex. The reconstruction of ancestral distribution shows that this complex originated in the Qinling mountains and surrounding areas during the early Pliocene, and then diverged with the range expansion and niche evolution. Species of the complex have different range dynamics. Based on our findings, we propose that niche evolution, range dynamics, and their coupling shape the distribution of species, which provides insight into the eco-evolutionary processes that formed the current distribution of species in theC. zawadskiicomplex.