bluuebunny/crossref_metadata_2025 huggingface dataset:
A propensity score matching investigation of short-term results of single-incision laparoscopic low anterior rectal resection via ileostomy site
Authors: Lai Jianxiong , Ye Pengcheng , Yang Junsong , Feng Yanchao , Qiu Kai , Wei Shoujiang
Published: January 2023

Aims:

The study was performed to verify the results of single-incision laparoscopic surgery (SILS) through the ileostomy site for low rectal cancer compared with conventional laparoscopic surgery (CLS).

Materials and Methods:

From January 2019 to November 2021, 133 patients with low rectal cancer underwent single-incision (n = 27) or conventional (n = 106) methods of low anterior rectal resection surgery with ileostomy. All patients were balanced by propensity score matching for basic information in a ratio of 1:2, resulting in 27 and 54 in SILS and CLS groups, respectively.

Results:

Relative to the CLS group, the SILS group exhibited fewer leucocyte changes, shorter time to first exhaust and first bowel sounds, shorter length of hospital stay and lower Visual Analogue Score on post-operative days (POD2) and POD3. Intraoperative or post-operative complications or readmissions were comparable between the two groups. The oncologic results remained consistent between the two groups other than the number of lymph nodes dissected in group no. 253.

Conclusions:

Single-incision laparoscopic low rectal resection surgery through the ileostomy site has advantages in terms of reduced post-operative pain, shorter post-operative exhaust time and length of hospital stay while also achieving oncologic outcomes similar to those of conventional laparoscopy. It can be an alternative procedure for patients with low rectal cancer who require ileostomy.
Laparoscopic-assisted transhiatal oesophagectomy: An experience from a tertiary care centre over 10 years
Authors: Kanchodu Sudheer , Nag Hirdaya Hulas
Published: January 2023

Background:

Minimally invasive surgeries have become the standard of care in oesophageal surgeries, but the transhiatal approach is still not widely in practice. As in the open surgical approach, laparoscopic transhiatal oesophagectomy has been accepted by many centres worldwide. The laparoscopic-assisted transhiatal oesophagectomy (LATE) has become a time-tested surgery. Many centres across the world have shown its feasibility and superiority regarding the lymph node yield with less morbidity with the added advantage of laparoscopy. We are pleased to share our 10-year experience with LATE and the long-term follow-up.

Materials and Methods:

Retrospective analysis of prospectively maintained data from our tertiary care centre from January 2010 to January 2021. Forty-six out of 74 patients with carcinoma of the lower end of the oesophagus who underwent LATE were analysed retrospectively.

Results:

Our study group included 46 patients. Six patients who required conversion to open surgery and those who underwent different procedures were excluded. The mean operative time was 220 (140–360) min. The mean blood loss was 230 (100–500) ml. Four (8.69%) patients had neck leaks. Twelve (26.08%) patients had minor pulmonary complications and one (2.17%) patient had a major pulmonary complication in the form of acute respiratory distress syndrome. The median hospital stay was 10.5 (8–28) days and 90-day mortality was 2.17%. 45 (97.82%) patients had an R0 resection rate with a median lymph node yield of 21 (16–28). The median overall survival was 44 months, with a 3 years disease-free survival rate of 63.04% and a 5-year overall survival rate of 36.50%.

Conclusion:

LATE is feasible and safe for adenocarcinoma of lower third esophagus and GEJ (gastroesophageal junction). The laparoscopic magnified view of lower mediastinum provides a better vision for lymphadenectomy especially in the neoadjuvant group. It has all the added benefits of minimal invasive surgery with acceptable short and long term oncological results.
Laparoscopic gastric wedge resection and spleen-preserving distal pancreatectomy performed on a 6-cm gastric desmoid tumour with pancreatic invasion
Authors: Kyun Park Jae , Kim Dae Hwan , Choi Chang In , Kim Kyung Bin , Park Young Mok
Published: January 2023

Desmoid tumours are rare tumours originating from fibroblasts, and are characterised by local infiltration and no metastasis. When complete resection is possible, surgical resection is considered a first-line treatment. In the case of large desmoid tumours, it is mainly performed by laparotomy, not laparoscopy. We report a case of a 43-year-old female patient presenting with a hypodense mass of approximately 5 cm in the posterior wall of the gastric antrum on computed tomography. There was no history of familial adenomatous polyposis, trauma or abdominal surgery. The patient underwent laparoscopic gastric wedge resection and spleen-preserving distal pancreatectomy without peri-operative complications. Pathological analysis revealed a desmoid tumour, which originated from the stomach and invaded the pancreas. Despite the large size and the locally infiltrative characteristics of these tumours, laparoscopic surgery can be an optimal treatment option due to its advantages.
Study on impact of flexible endoscopy training course for surgeons in India
Authors: Sundaram Easwaramoorthy , Chandrasekar Sakthivel , Agarwalla Ramesh , Govindaraj Kanagaraj , Desarkar Satyapriya , Yasmine Jaseema , Khanna Subhash , Manickavasakam Kanagavel , Popat Sunil D.
Published: January 2023

Context:

Competence in flexible endoscopy is essential for all surgeons during this era of minimal access surgery. However, fewer surgeons have expertise in endoscopy due to a lack of training and interest. The Indian Association of Gastrointestinal Endo Surgeons devised a short-structured training course in the art and science of endoscopy.

Aims:

This study aimed to find the impact of the endoscopy training course (Endoscopic Fellowship of Indian Association of Gastrointestinal Endo Surgeons [EFIAGES]) in improving the endoscopic skill of surgeons.

Settings and Design:

Twenty-two-part electronic survey forms were sent to all 375 candidates who took the course between 2016 and 2019 for this retrospective observational study.

Subjects and Methods:

The following outcome measures were noted, namely technical competence in endoscopy before the course, delegate feedback about the course modules, volume of endoscopies before and after the course and quality indicators such as reaching up to duodenum (D2) and caecum before and after the course.

Statistical Analysis Used:

Statistical analysis of the impact of the course was done using Chi-square test.

Results:

Responses from 262 out of a total of 375 candidates were received. Seventy-seven per cent of trainees were pleased with content and mode of conduct of the course. The quality indicator of gastroscopy with the ability to reach D2 in 90% of the caseload was achieved by only 28% of trainees before the EFIAGES. This increased to 72% of candidates after the course and similar results were seen with colonoscopy also. Most of the candidates noted a distinct improvement in their endoscopic navigation skills subsequent to the course.

Conclusions:

Endoscopy skill transfer was possible with a short-structured endoscopy course. The surgical fraternity should realise the importance of endoscopy skills in the current era of surgical practice.
JB Sharma’s white cotton ball sign: A new laparoscopic sign in abdominopelvic tuberculosis
Authors: Sharma Jai Bhagwan
Published: January 2023

Background:

Abdominopelvic tuberculosis (TB) is a variant of extrapulmonary TB causing significant morbidity, including infertility.

Materials and Methods:

Results of 87 cases of diagnostic laparoscopy in cases of abdominopelvic TB diagnosed on composite reference standard (CRS) for demonstration of new laparoscopic white cotton ball sign are presented.

Results:

Mean age, parity and duration of infertility were 27.2 years, 0.21 and 3.1 years, respectively. Oligomenorrhoea and hypomenorrhea were seen in 35 (40.22%) and 32 (36.78%) cases, while infertility was seen in all 87 (100%) cases while abdominal mass was seen in 27 (31.03%) cases and pelvic mass in 37 (42.58%) cases. Positive acid fast bacilli on microscopy and culture of endometrial biopsy was seen in 3.34% and 6.89% cases while epithelioid granuloma was seen in 12.64% cases on endometrial biopsy and in 13.79% cases on peritoneal biopsy. Positive polymerase chain reaction was seen in all cases while definitive abdominal pelvic TB was seen in 35 (40.1%) cases and probable findings in 42 (48.27%) cases. A new laparoscopic white cotton ball sign (resembling a large white cotton ball) was observed in 5 (5.74%) cases and biopsy from 3 showed it to be epithelioid granulomas positive.

Conclusion:

Demonstration of a new white cotton ball sign on laparoscopy seems to be a useful finding in abdominal pelvic TB.
The impact of the Epic Games v. Apple case on developer monetization and payment systems
Authors: Ward Julian , Farsimadan Elaahe
Published: January 2023

This article summarizes the key issues arising in respect of the US case Epic Games v. Apple; provides an overview of the related investigations and litigation in other jurisdictions and examines how Epic Games v. Apple may impact developers’ game monetization and payment system options and challenges moving forward.
Taxonomy for sustainable finance: a difficult topic for Europe, a worrying development for our democratic principles
Authors: Fouquet Dörte
Published: January 2023

This article aims to give a more detailed analysis concerning the new Taxonomy Regulation on sustainable finance of the European Union and the development as well as the current conflict on the main content of the second delegated Regulation of the European Commission. It outlines the legislative boundaries to issuing important topics such as in this case the subsumption of nuclear and fossil gas via the Commission Regulation as sustainable within the framework of the Taxonomy Regulation.
The right to adequate housing for IDPs in the context of slow-onset climate-induced disasters within the European Union
Authors: Lange Robert Max
Published: January 2023

The effects of climate change are projected to lead to significant displacement within the European Union (EU). However, internal displacement caused by slow-onset disasters has been neglected from discourse, and the EU lacks a legal framework for internal displacement. This article deploys an interdisciplinary approach to assess the protection offered to internally placed persons (IDPs) in this context: a legal analysis evaluates the right to adequate housing and a discourse analysis unpacks the construction of ‘forced displacement’ surrounding the non-binding Guiding Principles on Internal Displacement. Special attention will be paid to individual vulnerabilities and structural socio-economic constraints as drivers for internal displacement.

The findings reveal that the human-rights-based framework provides relatively weak socio-economic housing rights. Protection of adequate housing is only offered in reactive claims requiring proof of severe environmental impact. Moreover, IDPs were initially constructed as a distinct group characterized by direct violence and imminent disasters rather than structural constraints. While the discourse recently shifted to recognize the complexity of individual displacement experiences, no corresponding concept has been institutionalized. Thus, this article recommends that the EU draw inspiration from the Kampala Convention regarding its definition of internal displacement, the legally binding nature and proactive state obligations.
First Principles calculation of Half metallic proprieties of QCrAs (Q=Hf, Ti and Zr)
Authors: Babalola M. I. , Iyorzor B. E. , Ebuwa S. O.
Published: January 2023

The structural, electrical, magnetic, mechanical, and thermodynamic properties of some novel half-Heusler alloys QCrAs(Q=Hf, Ti and Zr) are investigated using first principles calculations. The results show that the three half Heusler alloys are half metals and they can find application in spintronics industries. They possess magnetic moment of 3\mu_B. The mechanical properties shows that they are mechanically stable. The B/G ratio of the three half-Heusler alloys show that they are ductile in nature and the Poisson’s ratio reveal that the plasticity of TiCrAs and ZrCrAs are higher than that of HfCrAs. The Debye temperature and average sound velocity of ZrCrAs is observed to be higher than the other two alloys. This implies that the thermal conductivity of ZrCrAs is the highest.
Fitrah Beragama dan Islam Agama Kaffah
Authors: Saputra Decky
Published: January 2023

Fitrah bagi manusia dalam beragama dan Islam sebagai agama yang mengatur dari setiap persoalan kehidupan manusia (kaffah). Manusia merupakan makhluk Allah paling istimewa yang telah dianugerahkan dengan berbagai fitrah-Nya, secara bahasa kata fitrah berasal dari kata fathara (فطر) yang berarti menjadikan. Kata tersebut berasal dari akar kata al-fathr (الفطر) yang berarti belahan atau pecahan. Manusia sebagai penghuni alam semesta ini ternyata terikat dengan hukum-hukum yang ada di alam semesta ini. Hukum alam semesta tersebut beroreantasi pada hukum-hukum Allah.
Review on a prospective study on drug use pattern in pediatric seizures
Authors: J Marurhi Sandeep , K Suzen Suma , M Sai Karan , Y Keerthana , P Narayana swamy
Published: January 2023

Objectives: The objective of this study is to evaluate the drug utilization pattern and to observe possible treatment outcomes. Methods: A Non-experimental prospective observational study has been carried out in tertiary care hospital for a period of six months. A total number of 181 paediatric inpatients of age 1- 14 years with seizures were included and evaluated. The patient case history was collected based on data collection form designed for the study. RESULTS: In our study we observed that female patients are more prevalent. Prevalence of seizures is high among age group 1-5years and low among 11-14 years. Tonic-clonic (51.3%) type of seizures was commonly observed, followed by febrile seizures (19%). Phenytoin is the mostly prescribed drug followed by sodium valproate. Monotherapy is observed mostly. Outcome of the therapy is measured by seizure free period, among which seizure free observed are more 74.1%. The incidence of ADRs in the study group is less (6.6%) and phenytoin is the drug with more number of ADRs. Medication adherence is measured in known epileptic patients (n=67) using MMAS, medium adherence seems to be more (49%). Conclusion: This study strongly highlights that the, Clinical pharmacist has a pivot role in conducting drug utilization studies that helps in comparing the ongoing regimen with the standard treatment guidelines so as to promote the stupendousity of rational use of drugs and to minimize or control the incidence of ADRs.
Analysis and Study of Expert System for Heart Disease using Artificial Neural Network and Data Mining Techniques
Authors: Saxena Swati
Published: January 2023

In today's culture, heart disease is a significant contributor to morbidity and death. Medical diagnosis is a crucial yet challenging process that needs to be completed precisely and effectively. The practical use of expert systems for heart disease employing several approaches, including Support Vector Machine, Radial Basis function, GRNN, and Feedforward Backpropagation, is shown in this study. In order to construct any kind of expert system based on symptoms, it is important to understand how data should be gathered and which factors are helpful. Many different kinds of strategies that are employed in constructing the expert system with technical features are among the factors highlighted. Another suggestion made in this article was to use data mining, Support Vector Machines (SVM), Genetic Algorithms, Rough Set Theory, Association Rules, and Neural Networks to identify cardiac disorders. We briefly looked at the effectiveness of the Decision tree and RBF for treating heart disease in this study compared to the other strategies. As a result, it is noted that data mining may aid in the detection or prognosis of high or low-risk cardiac illnesses.
Vol. 4, N.º 1, Jan-Jun 2023 - "Radiologia de Fusão - os melhores momentos"
Authors: Editorial Conselho
Published: January 2023

Sexta publicação da ROENTGEN - Revista Científica das Técnicas Radiológicas, edição especial dedicada aos melhores momentos do Encontro Nacional "Radiologia de Fusão".

Neste número da ROENTGEN pretendemos dar a conhecer ao leitor os melhores momentos que contribuíram para o grande sucesso de um evento científico que veio para ficar com a sua periodicidade bianual, a sua variedade, a sua pertinência e impacto.O conjunto de tudo isto resulta numa perfeita sintonia, a que chamamos Radiologia de Fusão.
Aspetos técnicos da injeção de contraste endovenoso na Angio-TC do Tórax para avaliação de Tromboembolismo Pulmonar - Estudo de caso
Authors: Araújo Rui , Nogueira Fábio
Published: January 2023

Introdução: Nos últimos três anos foi patente um aumento significativo dos exames ao tórax devido à COVID-19. Além da avaliação inicial do parênquima pulmonar, o recurso à Angio-TC para identificação de tromboembolismo pulmonar (TEP) ocupou um lugar de destaque na avaliação da vasculatura e perfusão pulmonar.

Materiais e métodos: De Maio a Outubro de 2022, todos os exames de Angio-TC para pesquisa de TEP realizados pelo mesmo profissional foram adquiridos com um máximo de 50 mL, recorrendo a protocolos otimizados para os equipamentos Philips® Brilliance de 64 cortes e Siemens® SOMATOM go.Up de 32 cortes. Em cada exame foi analisado o estado geral do doente, testado o cateter venoso e determinados os parâmetros de injeção mais ajustados. A localização do ROI e o número de Unidades de Hounsfield de referência variou consoante o paciente.

Resultados: O volume médio de contraste injetado em exames realizados no equipamento Philips® foi de 38,3 ± 3,7 mL e o fluxo de 3,3 ± 0,5 mL/s, sendo o tempo de aquisição, em média, de 3,9 ± 0,6 s. No equipamento Siemens®, o volume médio de contraste injetado situou-se nos 38,3 ± 6 mL, sendo a média do fluxo e tempo de aquisição de 3,2 ± 0,6 mL/s e 11,1 ± 1,3 s, respetivamente.

Conclusão: Para cada equipamento e paciente é imperativo a adaptação do volume de contraste a injetar para deteção de TEP. Volumes inferiores a 50 mL são suficientes para a demonstração da pequena circulação.
A relevância e eficiência das técnicas realizadas pela Radiologia de Intervenção no tratamento dos tumores hepáticos
Authors: Vasconcelos Cristina , Almeida Cristina , Conceição Neusa
Published: January 2023

Objetivo: Compilar estudos estruturais que suportem e comprovem a eficiência que a Radiologia de Intervenção assume no tratamento dos tumores hepáticos, como uma técnica minimamente invasiva, altamente diferenciada, reduzindo a necessidade de tratamento cirúrgico com uma melhoria na qualidade de vida dos pacientes.

Materiais e Métodos: O método a utilizar será o mnemônico PCC, sendo o P- a população alvo, o C- o contexto e o outro C- o conceito, que orientarão a pergunta da revisão. E será aplicado como referência o guia para relatórios de revisão PRISMA-ScR, alinhada ao guia do Instituto Joanna Briggs, constituindo instrumento fundamental para a transparência e confiabilidade deste tipo de revisão.

Resultados: Pela análise da literatura estudada existem ainda várias lacunas. Encontram-se na literatura Guidelines de boas práticas, no que toca ao diagnóstico e terapêutica pela Radiologia de Intervenção nos tumores hepáticos, apenas seria de realçar e aprimorar os documentos na literatura, para comprovar e suportar todas estas técnicas, enriquecendo ainda mais a comunidade científica.

Conclusão: A Radiologia de Intervenção é uma subespecialidade caracterizada pela tecnologia e modernização, focada em diagnósticos e tratamentos de última geração. Porém, ainda existe muito para explorar nesta especialidade e demonstrá-la cientificamente.
Integrated Planning of Park-and-Ride Facilities and BRT-Based Public Transport Services (Case Study of Campus Parking Optimization at Udayana University in Denpasar City)
Authors:   Civil Engineering, Faculty of Engineering, Udayana University, Bukit Jimbaran Campus, Bali-Indonesia, Diputra Gede Astawa , RakaMandi Nyoman Budiartha ,   Civil Engineering, Faculty of Engineering, Udayana University, Bukit Jimbaran Campus, Bali-Indonesia
Published: January 2023

One aspect that has not been considered in the process of transforming public transportation or angkutan umum (AU) in the Metropolitan Sarbagita area of Bali is integration, specifically physical integration (integration with walking, biking, and park-andride). We propose a framework for integrated parking planning at the University of Udayana (UNUD) campus in the city of Denpasar as an informal park-and-ride (PR) integrated with existing AU, specifically the Trans Sarbagita corridor 2 (City-GWK) which passes through the Denpasar and Bukit campuses in the Badung district. Integrated public transportation services are an attractive new form of service that combines fixed route services with responsive on-demand services. The goal of this study is to identify users of the PR at the UNUD campus and investigate their motives, demand, and preferences towards this option. In this paper, a comprehensive background is provided to describe the issues and challenges related to AU operations, directing research into the area of untapped issues by specifically discussing all the steps that must be taken when implementing an integrated approach at the operational and policy level towards sustainable mobility, transportation equity, and door-to-door services.
Instagram Coffee Shop Content Ideation for Pondok Aren (Bintaro) Community
Authors:   School of Business and Management, Institut Teknologi Bandung, Indonesia, Siswanto Rahadian Aslam , Belgiawan Prawira Fajarindra ,   School of Business and Management, Institut Teknologi Bandung, Indonesia
Published: January 2023

The development of the coffee shop industry in Bintaro, South Tangerang is becoming more numerous and varied, this has given rise to competition for customers. Therefor Coffee shop carries out Instagram activities as a channel to provide their content. However, 77.22% of coffee shops are dissatisfied with the performance of their Instagram. In the final project this aims to find out what content attracts the Bintaro Community and how this content influences brand equity. This study uses the PLS method with the independent variable Instagram Attractiveness (IA) and the dependent variables in the form of Brand Awareness (BA), Brand Image (BI), Perceived Quality (PQ), Brand Love (BL) and Brand Re-usage Intention (RI). Data collection used the Google form which was distributed to 210 respondents from the Bintaro community who use Instagram. From the results of the study, it was found that the Instagram Attractiveness variable was accepted and had a positive impact on Brand Awareness, Brand Image, Perceived Quality. Brand Awareness, Brand Image, Perceived Quality variables were accepted and had a positive impact on Brand Love and Brand Re-usage Intention. However, the Brand Awareness variable for Brand Re-usage Intention is rejected. It can be concluded that Menu, Ambience and Event content at coffee shops are attractive types of content and will have a positive impact on Brand Equity. The solutions given to coffee shops are planning, creating, and also posting menu content, events and also ambience with viral marketing strategies, building Instagram themes for brand images, and also using photography techniques to create content.
Severe Acute Respiratory Syndrome Related Coronavirus 2 (SARS-Cov2) Infection Among Doctors and Nurses After Introduction of Vaccination - A Tertiary Care Experience from Mumbai
Authors:   Dept of Pathology & Microbiology, Breach Candy Hospital Trust, Mumbai, India, Poojary Aruna , Patil Priyanka ,   Dept of Pathology & Microbiology, Breach Candy Hospital Trust, Mumbai, India, Rohra Seema ,   Dept of Pathology & Microbiology, Breach Candy Hospital Trust, Mumbai, India
Published: January 2023

Introduction : Acute Respiratory Syndrome related Coronavirus 2 (SARS-CoV2) is a novel Coronavirus causing the current pandemic. Among all the efforts to curtail the pandemic, vaccination is an important pillar towards halting transmission and reducing morbidity and mortality due to this disease. SARS-CoV2 has affected healthcare professionals (HCPs) globally . HCPs were a priority group that was vaccinated in the first phase in India. No vaccine is 100% effective. The effectiveness of the SARS-CoV2 vaccine in this high risk group needs to be studied.
Hepatitis-associated aplastic anaemia: surveillance of frequency, clinico-haematological features, and demographic distribution at a tertiary care hospital in Pakistan
Authors: Nawaz Muhammad Talha , Hameed Ayesha Nasir , Angez Meher , Ansari Ali Hussain , Adil Salman Naseem
Published: January 2023

Objective: We aim to document the frequency of HAAA cases among AA patients presenting at a tertiary care hospital, and to determine the most common agents (viral/drug induced) and Clinico-haematological features among HAAA patients at a tertiary care hospital.
Methods: This study was a retrospective review, conducted at a tertiary care hospital in Karachi, Pakistan.
Results: A total of 21 patients were included in the study. Hepatitis among the HAAA patients was viral in 17 cases, while 4 were idiopathic. All the patients acquired aplastic anaemia within 3-12 months of the Hepatitis episode and most presented with bleeding, bruises and petechiae.
Conclusion: This study indicates and proves that presence and prevalence of this disease in the Pakistani population is quite significant. Unlike the rest of the world, HAAA in Pakistan is not entirely of unknown aetiology, most of the cases can be associated with one of the Hepatitis viruses.
Keywords: Hepatitis, Aplastic Anaemia, Hepatitis Associated Aplastic Anaemia, IST, HSCT.
Evaluation of data analytics workshop using RStudio amongst medical students in Pakistan
Authors: Abbas Manzar , Hareem Rauf  , Javeria Bilal Qamar  , Syeda Ramlah Tul Sania  , Russell Seth Martins  , Zahra Hoodbhoy
Published: January 2023

A quasi-experimental study was conducted at the Aga Khan University, Karachi, Pakistan, to evaluate the outcomes of a series of workshops on 25 medical students’ statistical knowledge and acceptance of RStudio. The knowledge in each of the five sessions was assessed using pre- and post- knowledge-based quizzes. In addition, the Student's Attitude Towards Statistics (SATS-36) and the Technology Acceptance Model were used. Data analysis on RStudio revealed a statistically significant improvement in knowledge in all five sessions (p<0.05). SATS-36 showed statistically significant improvement in Cognitive Competence (p<0.001). RStudio had commendable acceptance with relatively high scores of Attitudes (behavioural intention, median = 6.00 [5.20-7.00]) and Utility (perceived usefulness, median = 5.20 [4.10-6.20]). In conclusion, medical students had improved statistical knowledge and acceptance towards the novel statistical tool. Hence, further studies must evaluate the effectiveness of RStudio when integrated as part of the medical curriculum.
Keywords: RStudio; Technology acceptance; Peer learning; Statistics.
Effect of Policy Network Manager’s Role on Public Policy Process Outcomes in the Road Transport Sector in Nairobi City County, Kenya
Authors: Ombagi Cornelius , Minja David , Muna Wilson
Published: January 2023

Purpose: The policy network managers play an important role of providing a vital link between government, the public, and the policy makers ensuring that policies are effectively communicated and implemented, and that public opinion is accurately reflected in the decision-making process. They also ensure coordination of the activities of stakeholders, supporting policy development, and helping to ensure that policy decisions are made in the best interests of the public. Therefore, to ensure that the public policy process outcomes are well achieved, the policy network manager’s roles must be well defined. Due to the recurring challenges in the policy making process in the transport sector in Nairobi City County Kenya, this study sought to explore the effect of policy network manager’s role on public policy process outcomes in the Road Transport Sector in Nairobi City County, Kenya.

Methodology: The study adopted a descriptive research design. The target population of the study was 470 policy actors in the road transport sector within Nairobi City County out of which 407 were purposefully sampled to respond to the questionnaire and 45 were sampled to participate in focused group discussions as well as key informant interviews. The sampling approach adopted was a purposeful sampling procedure. A mixed methodology was adopted whereby both quantitative and qualitative data was collected through structured questionnaires, Key Informant Interviews and focused group discussions. The quantitative data was analyzed through descriptive statistics that is mean, frequencies and percentages as well as regression analysis. On the other hand, qualitative data was analysed through thematic analysis and reported in a narrative format.

Findings: The findings indicated that an improvement in policy network managers ‘roles would result to a significant improvement in the policy process outcomes.

Recommendations: This study recommends the policy actors in the public policy making process in the transport sector in Nairobi City County, Kenya to increase visibility of the manager’s roles. The study also recommends for a need to build trust and relationships as well as embrace and support evidence-based information. Another recommendation is the need for the policy network manager to facilitate collaboration between stakeholders and facilitate the exchange of information and ideas.
Cybercrime-as-a-Service & AI-Enabled Threats
Authors: Mathew Alex
Published: January 2023

Some of the fast-expanding areas of concern in the realm of cybersecurity are cybercrime-as-a-service (CaaS) and AI-enabled threats. CaaS refers to the usage of online markets or platforms where people or organizations can buy or rent the equipment and services required to commit cybercrimes. Artificial intelligence-enabled threats are those that leverage machine learning and artificial intelligence to conduct cyberattacks. This article offers an overview of these two topics and suggests a way to deal with them. The suggested approach entails actions like recognizing and keeping an eye on online marketplaces and platforms that are used to buy or rent hacking tools and services, creating and implementing new security tools and technologies that can recognize and counter AI-enabled threats, regularly training staff and users in security awareness, updating and patching systems and software, and working with law enforcement to find a perpetrator.
Generalized Dirichlet problem for an ordinary delay differential equation with Dzhrbashyan – Nersesyan derivative
Authors:   Institute of Applied Mathematics and Automation KBSC RAS, Mazhgikhova M. G.
Published: January 2023

In recent decades, interest in the study of differential equations involving fractional derivatives has noticeably increased. This interest is due to the fact that the number of fields of science in which equations containing fractional derivatives arc used varies from biology and medicine to management theory, engineering, finance, as well as optics, physics and so on. In this paper, the generalized Dirichlet problem is investigated for a linear ordinary delay differential equation with Dzhrbashyan – Nersesyan fractional differentiation operator. A condition for unique solvability is obtained. The existence and uniqueness theorem to the solution is proved. The solution of the problem is written out in terms of the special function Wv (t), which is defined in terms of the generalized Mittag – Leffler function (Prabhakar function).
Estimates of φ – strong mean sequences of singular integrals of summation methods
Authors:   Abkhazian State University, Pachulia N. L. , Pachuliya N. N. ,   Abkhazian State University
Published: January 2023

Sufficient conditions are found in the work that the kernel satisfies for the singular integral φ – to be strongly summable by regular methods.
On some formulas for fractional integration of one Fox function with four parameters
Authors:   Institute of Applied Mathematics and Automation KBSC RAS, Khushtova F. G.
Published: January 2023

Solutions to many problems of mathematical physics, engineering and economics arc expressed through the so-called special functions. In the theory of special functions an important place is occupied by functions of the hypergeometric type. Many of them can be written in terms of the Meyer G-function. A generalization of the Meyer function is the Fox H-function. Some properties of this function can be obtained from its representation using the Mellin – Barnes integral. When deriving some formulas for this function for particular values of its parameters, due to the cumbersome writing of the Fox function, it is more convenient to use simplified notation. In this paper, we consider a special case of such a Fox function containing four parameters. For this function, Riemann-Liouville and Erdelyi-Kober fractional integration formulas arc obtained. An integral representation of the considered function h through the Mellin – Burns integral, we write out the conditions under which it converges absolutely, and the asymptotic expansions for this function for large and small values of the argument. The formulas proved in the paper are obtained using the indicated Mellin – Burns integral representation and the well-known integration formulas from power functions. For particular values of the parameters, the function under consideration yields some well-known elementary and special functions, and from the obtained formulas of fractional integration – the known integral values of these functions.
On the methodological features and errors of measuring the surface tension of aqueous suspensions
Authors:   Chechen State University, Dadashev R. H. , Dzhambulatov R. S. ,   Chechen State University
Published: January 2023

The paper analyzes the methodological features of measuring the surface tension of highly dispersed systems, which include bentonite suspensions. It is shown that bentonite suspensions arc complex nonequilibrium systems, when measuring the surface tension of which it is necessary to take into account the influence on its value of many factors, the main ones being dispersion and sedimentation. These factors have a significant effect on the measured value of surface tension. The non-equilibrium of the system under study leads to a time dependence of the surface tension, which significantly complicates the measurement of its dependence on temperature. To measure the surface tension of a bentonite suspension, a new method based on the superposition of measurement results obtained by two independent methods, the hanging drop method and the lying drop method, has been developed and tested. Sedimentation, when using these methods, leads to oppositely directed (relative to the surface) processes: in the first case, the surface of the drop enriches the particles of the solid phase, in the second -is impoverished. Experimental studies of the time dependences of surface tension have shown that in the hanging drop method there is a linear decrease in surface tension, in the lying drop method the surface tension increases linearly with time. Superposition of the results obtained by these methods allows us to find the value of surface tension at a given time. An analysis of surface tension measurement errors of the influence of various factors on the error in measuring surface tension of the developed method is carried out.
Language as a motivation to the motherland (by the example of the adyges at Kadyr Natkho)
Authors:   Maykop State Technological University, Khuako F. N.
Published: January 2023

The article analyzes the functional mission of the language as an instrumental mechanism operating within the consciousness of the Adyghe who is outside the Motherland. After considering a number of relevant theoretical aspects and concluding on their basis about the relevance of the issues of interaction between language and consciousness, the author turns to a specific text resource. The text of “Memoirs” of the compatriot Kadyr Natkho, who remained abroad, acts as the text in the work known in the Adyghe field. Analyzing the texts of some of his short stories and drawing conclusions on this basis about the mutual conditionality of the language and the consciousness of a compatriot, the author of the article associates the language with the power that builds individual thinking in its look at the Motherland both under mentality and under circumstances.
Traditional remedies for snakebite in Sudan
Authors: Agab Mohamed Ahmed
Published: January 2023

Purpose: The aim of this review is to collect information in the available literature (PubMed central, Google scholar, Science direct and Medline and others) to reflect on the traditional remedies used to treat snakebite in Sudan.

Methodology: This is a systemic electronic database review accomplished by searching randomly selected databases including: PubMed central, Google scholar, Science direct and Medline and others. Data concerning Sudan was selected and written in a narrative descriptive format.

Findings: The data collected was written in a narrative descriptive style including the classification of venomous snakes with specific reference to the magnitude of the problem in Sudan and a reflection on the global magnitude of the problem.

Unique contribution to theory, policy, and practice: Snakebite is considered one of the neglected tropical diseases in the tropical and subtropical regions including Sudan, the heart of Africa. The significance of this problem is related to the fact that the snakebite in Sudan is sometimes sadly fatal and affects the young farmers and herders impacting the agricultural economy which is the backbone of the economy of the country.
Head teacher Leadership Styles and Teacher Performance in Primary Schools in Kaabong District, Uganda
Authors: Akullo Elizabeth Akullo , Kamanyire Venance Kamanyire
Published: January 2023

Purpose: This study investigated the influence of headteacher leadership styles on teacher performance in primary schools in Kaabong District. Specifically, the study was to establish whether headteacher transformational leadership style had a significant influence on teacher performance; whether headteacher instructional leadership style had a significant influence on teacher performance; and whether headteacher transactional leadership style had a significant influence on teacher performance in primary schools in Kaabong District.

Methodology: The study adopted a cross-sectional descriptive survey research design in which structured questionnaires and face-to-face interviews were used to collect data from 308 respondents that included headteachers, directors of studies, teachers, pupil leaders and members of school management committees. The sampling of respondents was done mainly using simple random and census.

Findings: The study found out that most headteachers in primary schools in Kaabong used the three leadership styles in their management. However, the study found out that most of the respondents disagreed that teacher performance in the primary schools was good. The results of the linear regression showed that use of transformational leadership style had an insignificant influence on teacher performance; use of instructional leadership style had a moderate significant influence on teacher performance; and use of transactional leadership style had an insignificant influence on the teacher performance in the primary schools.

Unique Contribution to Theory, Policy and Practice: The findings of the study will provide a basis for policy makers to consider which leadership styles to emphasize in a bid to improve on teacher performance in schools. The findings from this study will provide an insight among head teachers on the importance of adopting appropriate leadership styles that can ensure good teacher performance in the primary schools. The findings will provide a basis for identifying the relationship between head teachers and teachers in forging best practices for improved teacher performance in schools.
Quality Attributes: Consumers’ Evaluation of Tailored Clothing in Ghana
Authors: Alhassan Haruna Alhassan , Appiah Ninette Afi , Ankai Boateng Kojo
Published: January 2023

Purpose: There are challenges in arriving at quality garments that meet the consumers’ specifications for Ghanaian fashion designers. To appreciate consumers’ conceptualization of quality attributes of tailored clothing produced by small-scale garment manufacturers, the study assessed the quality attributes of tailored clothing produced by small-scale garment manufacturers.

Methodology: The descriptive research design was adopted. The study further employed the quantitative data collection and analysis technique. This study’s population comprised all clothing product consumers in the Wa Metropolis in the Upper West Region of Ghana. In determining the sample size of consumers, the study resorted to the convenience sampling technique and selected a sample size of 400 consumers. Descriptive and inferential analysis and interpretation (mean and standard deviation) was used.

Findings: The study found that consumers are more likely to accept a manufacturer’s reputation or brand, the clothing’s price, and whether it seems perfectly tailored as indicators of the garment’s quality and that they do not evaluate the quality of tailored clothing based on convenience and how difficult it is to come by tailored clothing that fit accurately.

Contributions to Theory, Policy and Practice: The study provides insights into consumer behavior in the context of the clothing industry in Ghana and other developing countries and help in explaining how tailoring habits or industry may differ from other more developed countries. Practically, this is useful for manufacturers, retailers, and researchers in the clothing industry who are looking to understand consumer preferences and improve the quality of their products. The findings can be used to inform policies aimed at increasing consumer confidence in the quality of tailored clothing in Ghana which may include measures such as mandatory quality testing or certification programs.
Evaluation of The Hepatoprotective Effect of Plantago major Extract in A Rifampicin-Isoniazid Induced Hepatitis Rat Model
Authors: Pelapelapon Allen Albert , Rohmawaty Enny , Herman Herry
Published: January 2023

Tuberculosis (TB) is an ancient human disease caused by Mycobacterium tuberculosis which affects the lungs, making pulmonary disease the most common presentation. Herbal medicine began to be developed as hepatoprotection. The hepatoprotection effects of Plantago major extract on serum glutamic pyruvic transaminase (SGPT), liver tissue Malondialdehyde (MDA), and histopathological changes were evaluated in rifampicin and isoniazid-induced hepatitis rats. Thirty male Wistar rats were divided into 6 groups: Group I received 1 % PGA, with hepatitis induced in the remaining groups by rifampicin and isoniazid 50 mg/kg BW/day, group II was only given rifampicin and isoniazid, group III was given curcuma 10.8 mg/kg BW/day and groups IV (PM1), V (PM2), and VI (PM3) were given Plantago major extract at a dose of 20.3, 40.5, and 81 mg/kg BW/day, respectively. The rats were treated for 28 days. Administration of Plantago major extract (20.3 and 40.5 mg/kg BW/day) inhibited the elevation of serum SGPT and MDA levels, with less portal inflammation than the negative control group. The rats treated with the higher dose of 81 mg/kg BW/day had serum SGPT, MDA, and percentage portal inflammation equivalent to the negative control group. The Plantago major extract at a dose of 20.3 and 40.5 mg/kg BW can inhibit the elevated serum SGPT. Plantago major extract exerts dose-dependent hepatoprotection effects in a rifampicin-isoniazid induced hepatitis rat model by reducing elevated levels of SGPT, liver tissue MDA, as well as the percentage of portal inflammation.
HIGHLIGHTS

To the knowledge of the authors, there has been no comprehensive work dedicated to antituberculosis drugs
The administration of Plantago major extract showed hepatoprotector effects, as evidenced by the inhibition of elevated levels of SGPT, MDA, and a lower percentage of portal inflammation than the negative controls
Plantago major extract can be used as herbal medicine that can be juxtaposed with the main drug in TB patients

GRAPHICAL ABSTRACT
Antioxidant Activity and Chemical Constituents Identification by LC-MS/MS in Bio-fermented Fruit Drink of Morinda citrifolia L.
Authors: Nuengchamnong Nitra , Saesong Tongchai , Ingkaninan Kornkanok , Wittaya-areekul Sakchai
Published: January 2023

Noni bio-fermented drink is a fermented fruit of Morinda citrifolia L. Noni fruit is reported to be useful for a wide range of maladies, and consumers throughout the world perceive similar benefits. However, the existing evidence does have some limitations as far as its general application to noni fruit products. This study is intended to assess the quality of noni bio-fermented drink. The fruit was fermented using wild environmental yeast by a local entrepreneur. After 3 months, the mixture was filtered, sweetened, pasteurized, and bottled. The finish product was investigated for its antioxidant activity, total phenolic content and phytochemical constituents. Antioxidant activities exhibited profound results in term of 2,2-diphenyl-1-picryhydrazyl (DPPH) assay with an IC50 value of 14.94±0.76 μg/mL which was very close to that of Trolox at 8.47±0.16 μg/mL. The low phenolic content of 0.75±0.01 mg gallic acid equivalent (GAE)/g measured by Folin-Ciocalteu reagent method. The data of mass spectra and their fragmentations from LC-MS/MS identified 53 of 59 phytochemical compounds from the drink. Iridoid glucosides; asperulosidic acid, deacetylasperulosidic acid and monotropein as well as coumarin; aesculetin, scopoletin were identified as markers of this drink. Moreover, amino acids including organic acids, sugars and sugar in glycosidic forms were elucidated. Sulfur compounds in this drink namely 2-Sulfanylpropan-1-ol; 3-sulfanylpropan-1-ol, thiodiglycol and L-Methionine were identified as the possible cause of the pungent characteristic fragrance. As a result, noni fruit bio fermented drink encompasses numerous nutrients and biological compounds with potent antioxidant activity which could be stated as wellness drink for health merit.
HIGHLIGHTS

Chemical profiles of Thai noni fruit bio-fermented drink was established
Noni drink contains numerous phytonutrients and bioactive compounds
Flavonoids and Iridoid glycosides can be identified and selected as markers for quality control
LC-MS/MS is a powerful technique for identification of compounds
U2T program for product development

GRAPHICAL ABSTRACT
An Update Review on Novel Drug Delivery System
Authors: Prof. Shriniwas Mane  , Dr. S. K. Bais  , A. B. Trigune
Published: January 2023

The term "novel drug delivery system NDDS refers to procedures, preparations, tools, and systems for effectively introducing medicinal substances into the body. Since the beginning of time, humans have used plants for sustenance and medicine because they are nature's cure-alls. There are currently global efforts underway to locate herbal remedies in plants and introduce them to the market using an effective medicine delivery technology for people.