bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH LINGKUNGAN KEWIRAUSAHAAN TERHADAP PENGEMBANGAN WIRAUSAHA DI KABUPATEN SLEMAN
Authors: Haryani Sri
Published: November 2020

The emerge and growth of entrepreneurs are  expected to reduce unemployment and increase the prosperity.  The research objective  is to analyze the effect of  entrepreneurial environment (government policies and procedures, socio-economic conditions, skill of entrepreneurial and business, financial assistance, and non-financial assistance) to the growth of entrepreneurship. Entrepreneurial environment conducive expected to bring new entrepreneurs and develop existing entrepreneurs. Data were collected by a questionnaire distributed to 66 SMEs in Sleman. The sampling method using purposive sampling, while data analysis using SPSS 17.00. In this research, test instruments include the validity and reliability test, the results show that the entire statement item valid and reliable. Normality test, multicollinearity, and heteroscedasticity showed normal distribution of data, between independent variables does not occur multicollinearity problems, and found none problem heteroscedasticity. It can be concluded that the fators that affecting entrepreneurial growth in Sleman is socio-economic conditions, entrepreneurship and business skills, and financial assistance.
SIMULASI VARIASI JUMLAH DAN PERIODE INVESTASI DALAM MODEL PROFIT-LOSS SHARING DENGAN DANA TABARRU’
Authors: Murniati Wahyuning , Sumarti Novriana
Published: November 2020

Model profit and loss sharing merupakan salah satu bentuk sistem investasi yang diterapkan dalam keuangan Islam. Penerima investasi dan investor melakukan pembagian keuntungan dan kerugian secara adil. Model yang digunakan dalam jurnal ini merupakan modifikasi dari penelitian sebelumnya dimana investor memberikan modal kepada pedagang berpenghasilan rendah di pasar tradisional. Pedagang akan mengembalikan modal tersebut dengan tambahan bagi hasil ketika pedagang mengalami keuntungan. Dalam jurnal ini, dilakukan penambahan dana tabarru’ dalam model dengan menggunakan prinsip premi bersih dalam asuransi. Dana tabarru’ merupakan kumpulan dana yang berasal dari pedagang dimana jika terjadi kerugian maka pedagang akan mendapatkan dana itu kembali sebagai santunan. Selanjutnya, model ini diimplementasikan pada laba bersih harian pedagang di suatu pasar tradisional Bandung pada variasi jumlah dan periode investasi.  Dari hasil yang didapat, disimpulkan bahwa penerapan dana tabarru’ memberikan keuntungan yang lebih besar daripada model investasi sebelumnya.
HARGA MINYAK BUMI DAN EMAS DUNIA SEBAGAI PENENTU PERGERAKAN INDEKS SEKTORAL DI BEI PERIODE 2011 - 2015
Authors: Fadah Isti , Kristianto Dayu , Puspitasari Novi
Published: November 2020

Kenaikan harga minyak bumi meningkatkan biaya produksi perusahaan, sehingga harga barang yang dijual akan naik. Kenaikan harga barang berpengaruh langsung terhadap penjualan produk, yang selanjutnya berdampak pada keuntungan dan harga saham perusahaan.  Faktor lain yang berperan penting dalam perekonomian adalah harga emas. Harga emas dunia berpengaruh terhadap pergerakan indeks harga saham. Penelitian ini bertujuan untuk menganalisis pengaruh perubahan harga minyak bumi dan emas dunia terhadap pergerakan indeks saham sektoral. Populasi penelitian adalah Indeks Saham Sektoral, dengan menggunakan metode purposive sampling menghasilkan sampel 6 sektor saham. Data sekunder yang digunakan berupa harga minyak bumi west texas intermediate, harga emas london gold p.m. fix, dan data indeks saham sektoral tahun 2011-2015. Analisis data menggunakan regresi linear berganda. Hasil penelitian menunjukkan bahwa harga minyak bumi berpengaruh negatif signifikan pada 4 sektor, yaitu sektor industri dasar dan kimia, sektor aneka industri, sektor properti dan real estate, serta sektor infrastruktur, utilitas, dan transportasi. Sedangkan harga emas dunia tidak berpengaruh signifikan terhadap keenam sektor. Penelitian selanjutnya disarankan untuk mem- perpanjang periode penelitian sehingga diperoleh gambaran yang lebih baik tentang kondisi pasar modal.
MACROECONOMIC CAUSALITY TOWARD SHARE PRICE OF STATE OWNED ENTERPRISES
Authors: Sumantyo Riwi , Nugrahani Dian Indah
Published: November 2020

Penelitan ini bertujuan untuk mengetahui hubungan kausalitas variabel-variabel makroekonomi terhadap harga saham  BUMN (Badan Usaha Milik Negara)  yang tercatat di BEI (Bursa Efek Indonesia). Variabel makroekonomi meliputi pertumbuhan ekonomi, inflasi, kurs dan Jumlah Uang Beredar (JUB) dan harga saham BUMN bidang Infrastruktur meliputi PT. Perusahaan Gas Negara, Tbk, harga saham PT. Telekomunikasi Indonesia , Tbk dan harga saham PT. Jasa Marga, Tbk. Penelitian ini menggunakan pendekatan Vector Autoregrresion pada tingkat First Difference dan Kausalitas Granger. Hasil penelitian ini menunjukkan pertumbuhan ekonomi memiliki pengaruh positif signifikan, tidak terjadi hubungan kausalitas terhadap harga saham PT. Jasa Marga, Tbk serta negatif tidak signifikan pada harga saham PT. Perusahaan Gas Negara dan PT. Telekomunikasi Indonesia hubungan kausalitas searah terjadi pada harga saham PT. Perusahaan Gas Negara, Tbk dan PT. Telekomunikasi Indonesia, Tbk. Inflasi memiliki pengaruh postif tidak signifikan terhadap ke tiga harga saham BUMN bidang infrastruktur dan tidak terjadi hubungan kausalitas pada harga saham PT. Telekomunikasi Indonesia, Tbk dan PT. Jasa Marga, Tbk.
Rhetoric Strategies in the Presidents` Speeches: Ukrainian versus English
Authors: V. Nasakina Svitlana , M. Kolisnichenko Natalia , I. Rohalska-Yakubova Inna , I. Chepelyuk Nataliya
Published: November 2020

The article focuses on the prominent stylistic devices of the language, gives their definitions, and examines the effectiveness of their use in the political speeches of the Prime Minister of the United Kingdom of Great Britain and Northern Ireland, the Presidents of Ukraine, and the President of the United States of America. It studies the rhetorical strategies that help the speakers to achieve the desired goal effectively, and add persuasiveness to the addresses. The article aims to reveal the similar tendencies in rhetorical speeches used by the political leaders. The research method, which includes two stages, has been presented. The first stage consisted of material collection. The second stage consisted of two sub-stages of the study and included the description, and the systematization of the obtained data. The significance of the research lies in the fact that the similar traits in political speeches in different countries have been defined. The further studying of the political speeches of the political elites can enable to deepen the knowledge about rhetorical strategies in the sociolinguistic aspect.
PEMBINAAN KEMAMPUAN MENULIS PUISI DI PADEPOKAN IQRO DESA KOLAM KECAMATAN PERCUT SEI TUAN KABUPATEN DELI SERDANG
Authors: Adisaputera Abdurahman , Hadi Wisman , Hutagalung Trisnawati
Published: November 2020

Menulis adalah kegiatan mengolah isi pikiran yang dituangkan melalui tulisan. Tujuan pelaksanaan kegiatan ini adalah untuk meningkatkan kemampuan anak-anak di Padepokan Iqro Desa Kolam dalam menulis puisi. Meningkatnya kemampuan menulis puisi menjadi langkah awal untuk mempengaruhi minat anak-anak di Padepokan dalam memperkaya pengetahuan berliterasi sastra yang dimiliki. Karena salah satu kegiatan dalam berliterasi adalah menulis. Untuk itu diperlukan tindak lanjut, dalam hal ini pembinaan menulis puisi terhadap anak-anak di Padepokan Iqro Desa Kolam Kecamatan Percut Sei Tuan Kabupaten Deli Serdang. Metode yang dilakukan dalam pembinaan kemampuan menulis puisi ini adalah metode pelaksanaan dengan 3 tahapan yaitu tahap workshop, tahap pembimbingan dan tahap pembuatan laporan hasil kegiatan, juga metode pendekatan yaitu metode pendidikan, metode pelatihan dan praktik, metode bimbingan dan praktik. Hasil kegiatan pembinaan kemampuan menulis puisi tersebut mendapat respon yang positif oleh kelompok sasaran. Anak-anak di Padepokan memiliki antusiasme yang tinggi dalam kegiatan tersebut, terlihat dari keaktifan anak-anak dalam tanya jawab. Anak-anak mulai mampu menulis puisi dengan baik. Kemampuan itu dapat di lihat melalui buku ber-ISBN yang berisikan kumpulan puisi hasil tulisan anak-anak di Padepokan secara individu, yang menjadi luran dari pengabdian tersebut.
PROGRAM PENGEMBANGAN PRODUK UNGGULAN DAERAH (PPPUD) KERAJINAN TENUN SUTERA SENGKANG DI KABUPATEN WAJO BERBASIS KEARIFAN LOKAL SUKU BUGIS
Authors: Ardi Muhammad , Rakib Muhammad , Amir Faizal , Rauf Bakhrani A , Miru Alimuddin Sa'ban
Published: November 2020

Tujuan kegiatan PPPUD ini adalah: (1)  Memperkenalkan kepada mitra jadwal perencanaan produksi yang efisien dan efektif; (2) Melatih mitra membuat jadwal perencanaan produksi yang efisien dan efektif;  (3) Memperkenalkan kepada mitra desain motif kain tenun sutera yang berbasis pada kearifan lokal Suku Bugis; (4)  Melatih mitra membuat desain, mengembangkan desain, dan menenun kain tenun sutera yang berbasis pada kearifan lokal Suku Bugis.   Metode yang digunakan adalah sebgai berikut: (1) melakukan sosialisasi kepada Pemerintah Kabupaten Wajo dan industri mitra; (2) melatih dan mendampingi mitra membuat jadwal perencanaan produksi yang efisien dan efektif; (3) melatih dan mendampingi mitra membut desain, mengembangkan desain, dan menenun kain tenun sutera yang berbasis pada kearifan lokal Suku Bugis; (4) melakukan monitroing dan evaluasi.  Hasil yang dicapai adalah sebagai berikut: (1) mitra mengenali dan terampil membuat jadwal perencanaan produksi yang efisien dan efektif; (2) mitra mengenali dan termpil membuat desain, mengembangkan desain,  dan menenun motif kain tenun sutera yang berbasis pada kearifan lokal Suku Bugis
PENDAMPINGAN SISTEM PEMBELAJARAN ONLINE BERBASIS APLIKASI GOOGLE MEET BAGI GURU-GURU SMP IT DAARUL ISTIQLAL DAN SMP IT RAHMAT MARINDAL I, KECAMATAN PATUMBAK, KABUPATEN DELI SERDANG
Authors: Nasution Rafika Dewi , Saragih Farida Hanim , Sembiring Puan Suri Mira A
Published: November 2020

Peningkatkan kualitas pembelajaran pada siswa SMP IT Daarul Istiqlal dan SMP IT Rahmat melalui kegiatan pendampingan terhadap guru-guru dalam pengembangan sistem pembelajaran online berbasis aplikasi Google Meet bagi guru-guru. Kegiatan penelitian ini dilakukan dengan melakukan proses pendampingan sistem pembelajaran online berbasis aplikasi yang disebarluaskan kemasyarakat khususnya di sekolah-sekolah sebagai pemecah persoalan pengembangan pembelajaran di era pandemi covid-19.Berdasarkan hasil kegiatan didapat simpulan bahwa pembelajaran online dapat meningkatkan proses belajar mahasiswa yang lebih mandiri, kreatif serta inovatif. Apabila materi yang disampaikan pada google meeting dirancang secara detail, dan sistematis, maka pembelajaran bahasa inggris di SMP IT Daarul Istiqlal dan SMP ITRahmat Marindal I Kecamatan Patumbakdapat meningkatkan kualitas pengetahuan siswa. Kendala yang dihadapi dalam proses pembelajaran online ini dapat dilakukaan dengan kegiatan sosialisasi lebih intens diantara guru, guru dengan siswa. Selain itu, mencari solusi alternatif dalam menghadapi kendala diantaranya siswa mencari alternatif dengan memakai modem internet pribadi, warnet, atau dengan menggunakan aplikasi wifi.id berbayar yang telah disediakan oleh pihak sekolah guna meminimalisir kendala.  Secara umum, pembelajaran berbasis online ini manarik, menantang kemandirian siswa dalam belajar dan sebagai solusi terbaik di massa pandemic covid-19 yang menuntut physical distancing.
The Local Economic Impact of Natural Disasters
Authors:   Federal Reserve Board of Governors, Roth Tran Brigitte
Published: November 2020

We use county panel data to study the dynamic responses of local economies after natural disasters in the U.S. Specifically, we estimate disaster impulse response functions for personal income per capita and a broad range of other economic outcomes, using a panel version of the local projections estimator. In contrast to some recent cross-country studies, we find that disasters increase total and per capita personal income over the longer-run (as of 8 years out). The effect is driven initially largely by a temporary employment boost and in the longer run by an increase in average weekly wages. We then assess the heterogeneity of disaster impacts across several dimensions. We find that the longer-run increase in income per capita rises with disaster severity, as measured by monetary damages. Hurricanes, tornados, and fires yield longer run increases in income, while floods do not. The longer run increase in income tends to rise with recent disaster experience and is absent for counties with no recent experience. Finally, a spatial spillover analysis suggests that, while over the short- to medium-run, the regional and local impacts of disasters on personal income are similar, over the longer run the net regional effect may be negative, in contrast to the positive local effect.
Interdisciplinariedad y transdisciplinariedad en la investigación de Carol Ryff
Authors: Herce Fernández Rubén
Published: November 2020

Este artículo estudia la investigación realizada por la psicóloga Carol Ryff y quiere mostrar un ejemplo de cómo puede la filosofía colaborar con la ciencia experimental. Entre sus premisas está que la clave de una ciencia no es tanto la realización de experimentos contrastables, algo necesario en ciencia experimental, como su concordancia con la realidad. De ahí que el conocimiento específico de las diversas disciplinas, en algunos casos, tienda a agruparse en un movimiento primero multidisciplinar, después interdisciplinar y finalmente transdisciplinar. Normalmente esta tendencia no se concreta, pero en algunos casos como el mostrado sí. El proceso responde a una dinámica científica de avanzar en un conocimiento holístico que trasciende los límites o barreras levantadas por algunas interpretaciones de la actividad científica.
Javier García-Valiño Abós, La génesis del concepto de voluntad en Occidente. Un estudio desde las fuentes griegas y cristianas de Tomás de Aquino. Pamplona, Eunsa, 2019, 258 pp.
Authors: Molina Burgos Antonio Jesús
Published: November 2020

Reseña del libro La génesis del concepto de voluntad en Occidente. Un estudio desde las fuentes griegas y cristianas de Tomás de Aquino de Javier García-Valiño
Byung-Chul Han, Loa a la Tierra. Un viaje al jardín. Traducción de Alberto Ciria. Barcelona, Herder Editorial, 2019, 180 páginas.
Authors: Martínez Hermán Alba
Published: November 2020

Reseña del libro Loa a la Tierra. Un viaje al jardín de Byung-Chul Han.
Contemporary management of severe symptomatic bicuspid aortic valve stenosis: the BiTri Registry
Authors: De Biase Chiara , Siddiqui Saif , Brochado Bruno , Ziviello Francesca , van Mieghem Nicolas M. , De Backer Ole , Sondergaard Lars , Silveira João , Saint-Etienne Christophe , Bourguignon Thierry , Lange Rudiger , Jovanovic Marija , Berthoumieu Pierre , Bleiziffer Sabine , Tuccillo Andrea , Lemee Caroline , Chapdelaine Kevin , Dumonteil Nicolas , Tchetche Didier
Published: November 2020

Aims

A greater number of patients with bicuspid aortic valves (BAV) may be identified and treated as indications for transcatheter aortic valve implantation (TAVI) are expected to expand to younger patients. We evaluated the contemporary frequency and management of symptomatic patients with stenotic BAV in a multicenter European registry.

Methods

Between November 2017 and February 2018, all consecutive patients admitted for symptomatic aortic stenosis across six high-volume European hospitals were prospectively enrolled in the BiTri registry.

Results

Of the 832 patients, 17% (n = 138) had a BAV. The most frequent BAV phenotypes were type 1 (left--right coronary cusps fusion 64%) and type 1 (right-noncoronary cusps fusion 17%). Type 0 and type 2 accounted for 12 and 2%, respectively. When compared with tricuspid patients (n = 694), BAV patients were younger, with lower surgical risk. The transthoracic echocardiography (TTE) identified BAV in 64% of patients. Multisliced computed tomography (MSCT) additionally completed the diagnosis in 20% of patients. Surgical inspection finally identified the remaining undiagnosed 16% of BAV. A combination of TTE and MSCT was the most common diagnosis method for BAV. Surgical aortic valve replacement (SAVR) was the predominant therapeutic option for BAV (70%) whilst TAVI was performed in 26%.

Conclusion

BAV is frequently observed in symptomatic patients with aortic stenosis. These patients are younger, have a lower risk profile and are predominantly treated with SAVR as compared with tricuspid patients. However, TAVI is performed in almost one-third of BAV patients in contemporary European practice. TTE combined with MSCT identified 84% of BAV.
Evaluation of implant survival by analysing dental panoramic radiographs: 10-year retrospective study
Authors: Cesur Aydin , Gaş Selin
Published: November 2020

Background/Aim: Panoramic radiographs have been used widely for pre-implant evaluation and the preparation of treatment protocols. Panoramic radiography is often the first choice method for the implant placements because it gives information on the overall shape of the jaws, the position of the maxillary sinus floor and the nasal cavity floor, and vertical position of the mandibular canal and the mental foramen in relation to dental implants. The specific aim of the present study was to evaluate 10-year survival rate of dental implants by analysis of dental panoramic radiographs. Material and Methods: This retrospective study was conducted on 507 panoramic radiographs of 156 implant patients. Initial oral health status, proceedings of Restorative/Endodontic treatments before implant placement, missing number of teeth and edentulism types, finalization of implant related prosthetic treatments during controls, implant quality scorings at baseline/ controls and implant fails were analyzed. Results: The study results reveal statistically significant difference between the performed R/E treatment rates, according to the need for R/E treatments (p= 0.008). During the initial radiograph 96.1% of the implants were successful and 3.9% had satisfactory survival. At last control 86% of the implants were successful, 10.3% had satisfactory survival, 1% had impairment in survival and 2.8% were unsuccessful. The change in the last control compared to the initial radiograph is statistically significant (p= 0.000) regarding satisfactory survival. Conclusions: Long-term implant survival is not significantly affected by gender, age, type of edentulism, the presence of periodontal disease, R/E treatment needs, implant location, prosthesis type, and the presence of multiple implants.
The use of photodynamic therapy on medication-related osteonecrosis of the jaws: Animal study
Authors: Karapinar Gökay , Özdal Zincir , Ünür Meral , Vakur Olgaç
Published: November 2020

Background/Aim: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) was first introduced in 2003 and its scope was expanded by the name medication-related osteonecrosis of the jaw (MRONJ), since 2014. This study aimed to evaluate the effects of photodynamic therapy (FDT) on tissue samples by histopathological and histomorphometric examination and serum TRACP-5b (Tartrateresistant acid phosphatase-5b) measurement in rats. Material and Methods: 24 Sprague-Dawley male rats were divided into 3 groups comprising 8 animals. Zoledronic acid was administered to groups 1 and 2 and 0.9% sodium chloride was administered to group 3 intraperitoneally. After the injections were completed, dental extractions were performed. Photodynamic therapy was applied to group 2, three times a week for the two weeks after the extraction. In the 16th week, sacrification was performed. Rats were undergone histopathologic and histomorphometric evaluations. Results: Photodynamic therapy has led to a decrease in epithelial opening and inflammation and an increase in the formation of new bone. Serum TRACP-5b values were shown to decrease significantly in the presence of osteonecrosis. Conclusions: PDT was shown to be useful in reducing MRONJ risk in rats. As a serum biomarker, Serum TRACP-5b could be a valuable marker. Additional studies should confirm the findings.
Experimental Study of Post Installed Rebar Anchor Systems for Concrete Structure
Authors: Haidar Haidar H. , Mussa Faten I. , Dawood Abbas O. , Ghazi Ahmed A. , Gabbar Rassel A.
Published: November 2020

This study investigated the effectiveness of several types of adhesives used in post-installed rebar connections as a bonding agent between steel reinforcement bars and old concrete under pull out test. The experimental samples were; cylindrical samples of (150 mm dia. × 300 mm high) with anchors rebar of varying diameter (12 and 16 mm), different embedded length (100 and 150) mm with different holes’ diameters. The strategy of control were cast-in-place rebar concrete specimens while other samples are post-installed rebar concrete specimens of varied chemical adhesives as bonding agents, namely KUT EPOXY ANCHOR ‘NS’ and SIKAFLOOR169. The output showed that the different adhesives yielded closed pull-out load values. It is found that the pull-out capacity (bond strength) is increased by increasing the embedded length, the diameter of the rebar and slightly with the diameter of the hole. In addition, the failure mode of post-installed rebar concrete was governed by the embedded length and the area of contact with the adhesives. On the other hand, the larger diameter of rebar favors splitting or failure of concrete due to higher strength in binder-rebar interface compare to the binder-concrete interface. The results showed that the pull-out load was increased by (26 % and 32 %) as the rebar diameter increased from 12 mm to 16 mm for KUT “NS” and SIKAFLOOR respectively. The hole diameter had slightly effect of the pull out load where the average of increment was only 6 %. Finally, the bonding strength is considerably depended on the embedded length and less affected by the type of epoxy.
Outdoor Climate Change Analysis in University Campus: Case Study with Heat-Air-Moisture Simulation
Authors: Juras Peter , Jurasova Daniela
Published: November 2020

The standard weather station network, belonging to the national weather forecast service, cannot satisfy the requirements of advanced simulation tools because of the network density, time interval of recording, collections of measured values or availability of measured data and its price. Due to the outdoor climate change, urban heat islands and advance in research it is vital to obtain precise data sets for the measured location. Since 2014, also the experimental weather station, which continuously records the wind flow, air temperature, humidity, solar radiation, rain and atmospheric air pressure, is a part of University of Zilina campus.

In this paper, measured values of selected climate parameters are analyzed in terms of raw data and also in the case study of two wall types – traditional masonry brick wall and lightweight wooden-frame wall. Behavior of these walls is simulated by the impact of a non-steady state with use of WUFI Pro software. The impact on the hygrothermal regime of walls – water content, simulated under various boundary conditions, is analyzed and the differences between measured years are quantified.
Acute Eosinophilic Pneumonia Due to Vaping-Associated Lung Injury
Authors: Wolf Molly , Richards Jeremy
Published: November 2020

A case is described of a 29-year-old female who presented with acute hypoxic respiratory failure due to acute eosinophilic pneumonia, associated with the use of electronic cigarettes to vape tetrahydrocannabinol (THC), together with the contemporary clinical understanding of the syndrome of electronic-cigarette associated lung injury (EVALI). Attention is drawn to acute eosinophilic pneumonia as a potential consequence of vaping-associated lung injury to understand the diagnostic evaluations and therapeutic interventions for acute eosinophilic pneumonia associated with vaping THC.
Functional classification of small towns in Germany. A methodological comparison
Authors: Gareis Philipp , Milbert Antonia
Published: November 2020

The development of small towns in Germany in terms of their economic, demographic and social endowment is a subject area that has been rather neglected so far. What is more, research often focuses exclusively on small towns in rural and peripheral regions, because this is the only place where they are assigned a certain role. Small towns in central areas, on the other hand, are subsumed under suburbia in research and are thus rarely considered in terms of their specific functions. In this paper, all small towns in Germany are classified with regard to important functions. The typification is done by means of a cluster analysis based on central factors, which in turn are tied to a broad set of indicators. Reference points are the classical method of principal component analysis and, as an alternative method, to geographically weighted principal component analysis. The methodological comparison shows that the alternative method – also due to the high computational effort – is not yet a suitable method for describing spatial relationships between the variables and for small towns with regard to existing functions in their surrounding areas. On the other hand, the approach of the principal component analysis, cluster analysis and discriminant analysis, which is found in the literature, produces well defined and explainable solutions for the formation of different types of small towns in Germany.
Endoscopic ultrasound-guided drainage of a fungal liver abscess using a lumen-apposing metal stent: case report and literature review
Authors: Molinario Felice , Rimbaş Mihai , Pirozzi Giuseppe Alessandro , Rizzatti Gianenrico , Spera Gianluca , Costamagna Guido , Larghi Alberto
Published: November 2020

Liver abscesses are rare entities for which percutaneous drainage is traditionally employed. The technique is simple, but associated with a significant rate of side effects and patient discomfort. We herein report a case of fungal left liver lobe abscess that was successfully treated by using EUS-guided drainage, with insertion of a large caliber lumen-apposing metal stent. The literature review we performed on the topic seems to favor, at least for abscess in the left and/or caudate liver lobes, EUS as compared to percutaneous drainage.
Epidermal growth factor receptor and STAT3 signal through KRAS have mutually opposite effects on CTEN
Authors: AlGhamdi Saleh , Ibrahim Salih , Balloch Kanwal , Jackson Darryl , Ilyas Mohammad
Published: November 2020

Background: C-terminal tensin-like (CTEN) is a protein located at focal adhesions and has been reported to be an oncogene in the colon, breast, lung, and gastric cancer. In this study, we investigated whether two other proposed mechanisms, i.e., epidermal growth factor receptor (EGFR) and Signal transducer and activator of transcription 3 (STAT3) signaling were involved in regulating CTEN expression.
Methodology: Initially, we manipulated EGFR signaling by (i) stimulation with epidermal growth factor (EGF) and (ii) inhibition by the PD153035 in the colorectal cancer cell lines SW620 and C32. In C32, EGF stimulation resulted in the upregulation of KRAS and CTEN, whereas exposure to PD153035 resulted in the downregulation of both KRAS and CTEN. EGFR activation and inhibition were reflected by, respectively, increased and
decreased cell motility although the effect of EGFR activation was lost by CTEN knockdown. In SW620, which harbors a KRAS mutation, modulating EGFR activity in this way did not affect either KRAS or CTEN. STAT3 signaling has also been reported to positively regulate CTEN. We tested this in SW620 by directly knocking down STAT3 and exposing cells to interleukin-6 (an activator of STAT3). STAT3 knockdown resulted in increased CTEN, whereas STAT3 activation resulted in the downregulation of CTEN.
Results: Testing for KRAS expression showed that STAT3 was negatively regulating KRAS, and this was reflected in the CTEN expression. Functional analysis, however, showed that the inhibition of STAT3 resulted in a reduction of cell motility in a K RAS and CTEN-independent manner.
Conclusion: We conclude that both EGFR signals through KRAS to modulate CTEN (and consequently integrin- linked kinase/focal adhesion kinase) and stimulates cell motility. STAT3, however, negatively regulates KRAS and consequently CTEN although its net effect is to stimulate motility through an alternative mechanism.
Nicho de Aprendizagem Matemática: uma experiência de ensinar e aprender matemática em convivência
Authors: Giron Graziela Rossetto , Sacramento Soares Eliana Maria do
Published: November 2020

Apresentamos resultados de uma pesquisa que objetivou desencadear a emergência de dinâmicas de cocriação de atividades que pudessem favorecer a aprendizagem matemática, à luz de alguns conceitos da teoria da Biologia do Conhecer. Por meio desta “experiência de convivência”, envolvendo a professora e os alunos do 8º ano do Ensino Fundamental de uma escola municipal da Serra Gaúcha, foram vivenciadas atividades relacionadas à exploração do Minecraft. O contexto no qual se desenvolveu essa experiência educativa foi denominado Nicho de Aprendizagem Matemática. Os resultados revelam pistas, possibilidades que indicam que quando os processos de ensinar e aprender estão apoiados em dinâmicas que favorecem a cocriação pedagógica, a aprendizagem acontece naturalmente e torna-se prazerosa.
Jogos matemáticos como recurso didático no ensino da subtração: o discurso docente
Authors: Páscoa Emanuela Galvão , Godinho Mara Silvana Ferreira , Targino de Moura Francisco Marconcio
Published: November 2020

Nosso objetivo, nessa pesquisa, foi investigar que contribuições os professores atribuem aos jogos matemáticos como recurso didático para superação de dificuldades no trabalho pedagógico da subtração. A pesquisa foi realizada tendo uma abordagem qualitativa, onde escolhemos como método a pesquisa exploratória. Para a coleta de dados trabalhamos com documentos e entrevistas. As possibilidades com os jogos, demonstradas dentro da pesquisa, foram inúmeras, desde a construção de conceitos a conhecimentos anteriores ao entendimento propriamente dito da subtração. Essa relação vai desde a possibilidade do jogo como estratégia para o conhecimento matemático à prática e disponibilidade do professor, visando a possibilidade de um trabalho fundamentado e integrativo entre professores e alunos.
Palavras-chave: Jogos Matemáticos; Subtração; Prática Pedagógica
Macrophage Activation Syndrome - An Unusual Complication Of SLE
Authors:   Armed Forces Medical College, Kumar Sumit
Published: November 2020

Macrophage Activation Syndrome (MAS) is a rare and potentially fatal condition that can complicate many autoimmune diseases. It is a type of Hemophagocytic Lymphohistiocytosis (HLH). HLH is a potentially fatal disease of normal but overactive histiocytes and lymphocytes commonly occurring in infancy but can occur in all age groups. There are two types of HLH: Familial and acquired. Familial HLH is an autosomal recessive disorder and accounts for 25% of the cases. Acquired type is secondary to drugs, malignancies, rheumatological disorders. There are five subtypes of inherited HLH: familial HLH and types 1-5. HLH may result from an inappropriate immune response to a viral illness like EBV. It may be due to X-linked Lymphoproliferative Disease (XLP) caused by a mutation in SH2D1A or XIAP gene. Usually, MAS term is used for HLH secondary to rheumatological disorders that occur mostly in individuals with Systemic Juvenile Idiopathic Arthritis (SJIA) and those with adult-onset Still disease. The condition is thought to be caused due to excessive activation and expansion of T lymphocytes and macrophage histiocytes that show hemophagocytic activity. The expansion of these cells leads to a massive systemic inflammatory response associated with three cardinal features: cytopenias, liver dysfunction, and coagulopathy, resembling Disseminated Intravascular Coagulation (DIC). MAS incidence in SLE patients is estimated to be 0.9% - 4.6%, and it is widely under recognized and underreported. In this report, we enumerate one such case with their clinical presentation, evaluation, and management.
Decision of Judges on Proof of Narcotics Rised for the State
Authors: Pranomo Andy
Published: November 2020

Pancasila as the source of state law, the placement of Pancasila as the source of all sources of state law is in accordance with the Preamble of the 1945 Constitution of the fourth paragraph, namely Almighty Godliness, Just and Civilized Humanity, Indonesian Unity, Democracy Led by Wisdom in Consultation and / Representative, and Justice for All Indonesian People. The position of Pancasila is the basis and ideology of the state as well as the philosophical basis of the state so that any material contained in the laws and regulations must not conflict with the values of Pancasila. Pancasila can be applied in everyday life, in this case the values of Pancasila can be seen in the role of the prosecutor in the execution of narcotics crimes at the Metro District Attorney's Office, which is more dominant as a factual role, because it is based on the fact that the prosecutor who carried out narcotics evidence was confiscated for state, law enforcement by judges on evidence of narcotics in the Metro District Court Decision. In his consideration that the evidence presented by the public prosecutor before the court and confirmed by the defendant is a tool or object used in the crime. Narcotics, which refers to Article 101 paragraph (1) of Law Number 35 of 2009 concerning Narcotics, explains “Narcotics, Narcotics Precursors and tools or goods used in Narcotics and Narcotics Precursors or related to narcotics and Narcotics precursors. The role of the prosecutor in executing booty from narcotics crime at the Metro District Attorney is more dominant as a factual role, because it is based on facts, namely the prosecutor executed based on the Metro District Court Decision Number: 132/Pid.Sus/2015/PN.Met. Then the factors inhibiting the prosecutor in executing booty from the crime of narcotics at the Metro District Attorney are: Obstacles in executing narcotics evidence confiscated for the State, namely juridical and nonyuridical obstacles. The purpose of this research is to understand how the judge's verdict on narcotics evidence is confiscated for the state. The research method used is the Normative and Empirical methods.
Relokasi Mandiri Permukiman Desa Gurukinayan Akibat Kejadian Erupsi Gunung Api Sinabung Kabupaten Karo
Authors: Manurung Rudi Kristian , Trimurni Februati
Published: November 2020

Gurukinayan Village is being relocated because this village is located in the Disaster Prone Areas Region (KRB) III. Gurukinayan Village was relocated to a safer place so that the community could have a decent life. Relocation has been slow due to government support still low, both political and administrative support. This research identifies the community's opinion on the relocation of settlements, analyzes the location of the relocation destination and examines what happens in the settlement relocation plan. Bardach states there are criteria for looking at independent relocation in the village of Gurukinayan, these criteria complement legaly, political acceptance, and robustness in conditions of administrative implementation, and improvability. The method used is a qualitative research method. Research data obtained through observation and interviews, also includes literature review and data from government organizations that require independent relocation. Based on the research results, in the eradication of the Mount Sinabung eruption disaster, there have been recommendations for the design of financial problems policies and the availability of ready-made funds that can be accessed by the Karo Regency BPBD. However, efforts to improve policies to create alternative solutions have not yet arrived at plans to make preparations for effective improvement of the eruption of the Mount Sinabung disaster. The results of this study offer a new concept, namely the discussion of the implementation of the Sinabung eruption disaster management policy must be supported by the community, protection, and professional organizational capabilities so as to be able to support access to law and political policy and support resilience in conditions of administrative implementation and improvability.
Implementation of Education Rights Fulfillment for Street Children by the Local Government
Authors: Virgonia Aurora , Hanida Rozidateno Putri , Putra Roni Eka
Published: November 2020

Children and education are two related elements to each other. Both the central and local governments have also issued policies that govern the education of children. But in fact, education for the street children has been still faced with some obstacles during the implementation. This research was conducted in Padang Municipality. This research was the result of the field studies to describe and analyze how was the effort of the fulfillment of the education rights of the street children in Padang Municipality. The research was conducted using qualitative research method where data collection techniques by interviews with several related stakeholders to this policy, observed the phenomena that have related to the policy, and do library research from any references such as the government's document and scientific research and tested with by triangulation sources techniques. The research result shows that there are some difficulties during the fulfillment of street children's education to implement by the few stakeholders. In addition, the incapability of these polices to provided clarity to each process of the policy implementation so that the output of the policy has not been able to be reached to the maximum
HUBUNGAN ANTARA HYPERLAXITY DENGAN KEJADIAN FLAT FEET PADA ATLET PENCAK SILAT PELATDA DKI JAKARTA
Authors: Wardhani Putri Kusuma
Published: November 2020

Cedera berbanding lurus dengan daya tahan atlet, menurunnya daya tahan atlet disebabkan oleh banyak faktor salah satunya adalah hyperlaxity. Hyperlaxity adalah kondisi jaringan ikat sendi (ligamen) yang terlalu lentur. Cedera sering pada olahraga high impact. Pencak silat termasuk olahraga high impact. High impact dapat berdampak pada kaki yaitu terjadinya flat feet yang merupakan keadaan lengkung longitudinal kaki mengalami penurunan. Menurut teori salah satu penyebab jangka panjang  flat feet adalah hyperlaxity. Tujuan: Mengetahui hubungan antara hyperlaxity dengan kejadian flat feet pada atlet pencak silat untuk mengurangi risiko cedera bagi atlet. Metode: Analitik observasional dengan pendekatan cross-sectional (potong lintang) pada 54 atlet pencak silat dengan kuesioner, score beighton dan foot print test dan Teknik pengambilan sampel menggunakan metode total sampling. Hasil: Uji statistik menunjukan adanya hubungan hyperlaxity dengan kejadian flat feet p=0,028 (p<0,05). Kesimpulan: Terdapat hubungan antara hyperlaxity dengan kejadian flat feet pada atlet pencak silat pelatda DKI Jakarta periode 2017-2020.
PERBEDAAN EKOKARDIOGRAFI PADA JANTUNG ATLET, HIPERTENSI, DAN KARDIOMIOPATI HIPERTROFI
Authors: Hasye Finesa , Yanni Mefri
Published: November 2020

Hipertrofi ventrikel kiri didefinisikan sebagai peningkatan massa ventrikel kiri. Peningkatan massa miokard karena latihan intensif yang teratur "jantung atlet" merupakan hal yang biasa. Meskipun terdapat korelasi langsung dengan beban latihan, hipertrofi miokard tidak hanya terjadi pada atlet. Jantung atlet dianggap sebagai fenomena fisiologis tanpa menimbulkan bahaya. Namun, bentuk lain hipertrofi miokard seperti kardiomiopati hipertrofi atau penyakit jantung hipertensi berhubungan dengan peningkatan risiko kejadian kardiovaskular. Echocardiography memainkan peran penting dalam diagnosis, strategi manajemen, dan prognostik penyakit kompleks ini. Perbedaan antara hipertrofi fisiologis dan patologis mungkin memiliki dampak besar, karena kardiomiopati hipertrofi yang tidak terdiagnosis merupakan salah satu penyebab paling umum kematian jantung mendadak pada atlet, sedangkan identifikasi penyakit kardiovaskular pada atlet dapat menjadi dasar untuk diskualifikasi dari kompetisi. Tinjauan pustaka ini akan membahas perbedaan hipertrofi fisiologis dan patologis.Kata kunci: Hipertrofi ventrikel kiri; jantung atlet; kardiomiopati hipertrofi; penyakit jantung hipertensi.
The structural and optical properties of Al and Mg doped ZnO synthesized by solid state reaction method
Authors: BİLGİLİ Özlem
Published: November 2020

In this study, the structural and optical properties of Al and Mg doped zinc oxide Zn0.98M0.02O (M= Al, Mg) prepared by solid state reaction method is investigated. X-ray diffraction (XRD), Scanning Electron Microscopy (SEM), UV-Visible spectroscopy (UV–Vis) and Fourier Transform Infrared (FTIR) spectroscopy were employed to study the structural and optical properties. With XRD analysis, it was revealed that all the samples are hexagonal wurtzite structure and exhibit no impurity phases. The reflectance spectra was used to determine the optical band gap of the samples. And it was found that undoped ZnO sample has an energy band gap of 3.16 eV which increases with Al and Mg doping, probably driven by the decrease in the lattice parameters. The structural bond vibrations of undoped and doped ZnO were analysed by FTIR spectroscopy, and it was seen that the broad absorption band is at approximately 550 cm-1 for all the samples, which corresponds to the stretching vibration of Zn–O bond.
Cryptocurrency potential in the context of transition of global economy to the sixth technological paradigm
Authors: Safiullin Marat Rashitovich , Savelichev Mikhail Valer'evich , El'shin Leonid Alekseevich
Published: November 2020

This article explores the potential of using cryptocurrency as universal currency in the conditions of transition of the global economic system towards sixth technological paradigm. The goal of this research consists in analysis of the patterns of co-evolution of the global financial system, technological system, and global economy. Based on the historical material, the author demonstrates how shift in technological paradigms is accompanied by financial crises, and result in the changes of the world financial system. Over the course of time, the gold served as the universal currency, but the advancement of technologies demanded the transition towards more flexible forms of world currency based on the national currencies of most industrialized countries. Currently, the transition to the technology of the sixth technological paradigm is followed by the global financial crisis. The U.S. dollar is not handling the functions imposed by the latest technologies upon monetary systems. The conclusion is made that finite currencies are being replaced by an innovative generation of monetary systems that are based on cryptocurrency. The authors systematize the innovation forms of investment, accounting, keeping and saving of funds, which are based on cryptocurrency and blockchain. It is demonstrated that innovation financial instruments, including different types of cryptocurrency, tokens, smart contracts, and cryptocurrency exchanges, open new opportunities for effective investment in the technologies of sixth technological paradigm. The results of research can be valuable for the government branches in establishment of the policy for usage of cryptocurrency and blockchain for entrepreneurs dealing with developments in the area of practical implementation of cryptocurrency as innovative currency.
Attempts of self-presentation and introspection of the political elite representatives of the Principality of Montenegro (to the question on peculiarities of political culture of Montenegrins at the turn of the XIX – XX centuries)
Authors: Khlebnikova Varvara Borisovna
Published: November 2020

History of the Principality of Montenegro, proclaimed after several centuries of consistent struggle with the Ottoman Empire, was quite short. As an independent state, it existed from 1878 to 1918. The reasons are explained by the political culture and level of professional qualifications of the Montenegrin elite, which had to resolve most difficult challenges dictated by the delayed and accelerated modernization of the country. The goal of this article consists in determination of significant characteristics of the Montenegrin ruling class, which substantiate the successes and failures of the principality. Two most prominent Montenegrin politicians of this time, Crown Prince Nicholas of Montenegro and Foreign Minister Gavro Vuković attempted to assess the results that were achieved, as well as their role in the political processes. A comparative analysis carried out on their narrative heritage, assessments given by the contemporaries, and archival materials led to the conclusion that the supreme leaders of Montenegro to the fullest extent possessed the qualities that were inherent to the people as a whole. Political culture of the Montenegrins, which has not previously become the subject of research within the Russian science, remained patriarchal and retained vestiges of tribal structure that impeded establishment of the state of modern type. Several centuries of hostile encirclement and permanent war, put the Montenegrins noticeably behind with regards to the development of education. Therefore, there was a severe shortage of managerial human resources. The low level of professional competence of the elite was compensated by placing emphasis on the military past and traditional values. However, the excessive warlike attitude led to reassessment of their powers, mismanagement with regards to domestic and foreign policy, as well as impeded the development of statehood of Montenegro. The acquired results may be valuable for culturologists and political scientists as the empirical material for studying such complicated concept as the political culture.
Women's issue at the dawn of establishment of civil society in Vladimir Governorate (February – October 1917)
Authors: Akimova Tatiana Mikhailovna
Published: November 2020

This article explores the establishment of civil society in Vladimir Governorate between the February and October Revolutions of 1917. Women for the first time became legally its full-fledged subject. Based on the documents preserved in the State Archive of Vladimir Region, State Archive of the Russian Federation, press materials (newspapers “Staryi Vladimirets”, “Vladimirskaya Zhizn”, "Svobodny Muromsky Golos”), the author examines the perception of the political events of that time by women of the governorate; outlines the urgent problems that women were concerned with; describes attitude towards the received suffrage and areas of manifestation of their social activity; as well as perception of the new in women’s rights by male part of the population. After the February Revolution of 1917 in Russia, the important steps were taken towards establishment of civil society with women being its full-fledged subject. Among the residents were not engaged in the revolutionary movement, most activity demonstrated the townswomen. They supported the implementation of universal suffrage, created women's communities, and participated in the discussion of urgent problems. Peasant women were mainly concerned with survivability of their families during difficult times. They were not familiar with the political life of the country and governorate, and unaffected by electoral campaigns into the district self-governance. This was justified by their tough financial situation, patriarchal structure in families, and lack of education.