bluuebunny/crossref_metadata_2025 huggingface dataset:
Efficacy of rituximab in autism spectrum disorders associated with hereditary folate malabsorption with signs of antineuronal autoimmunity
Authors: Maltsev D.V.
Published: October 2021

Background. One of the key advances in psychiatry is an elucidation of the association of hereditary folate malabsorption (HFM) with autistic spectrum disorders (ASD), the evidence for which is based on the results of 5 meta-analyses of randomized controlled trials. It is shown that in such cases the antineuronal autoimmune reaction is an important mechanism of encephalopathy formation. The purpose of the study was to investigate the efficacy of rituximab in children with HFM-associated ASD who showed serological signs of antineuronal autoimmunity to expand the current arsenal of neuroprotective therapy in immunodependent encephalopathy in such cases. Materials and methods. Medical data of 138 children aged 3 to 8 years with HFM and ASD (97 boys and 41 girls) were analyzed. Parents of 62 of 81 patients with signs of antineuronal autoimmunity agreed to rituximab immunotherapy at a dose of 375 mg/m2 of body surface area per month for 3–9 months (study group, SG). Relatives of the other 19 patients with a similar distribution of antineuronal autoantibodies refused treatment (control group, CG). The dynamics of the mental state of children during immunotherapy was assessed by the ABC scale. For statistical analysis, we calculated the parametric Student’s t-test with the confidence probability p and the non-parametric criterion — the number of signs Z by U.V. Urbach, as well as the odds ratio (OR) and 95% confidence interval (95% CI). Results. Rituximab treatment resulted in a progressive decrease in serum antineuronal autoantibodies concentration in patients with ASD associated with HFM, with a more pronounced effect in the production of autoantibodies to neuronal potassium channels compared to autoantibodies to the GADA with complete elimination of the seropositivity after a 9-month course of immunotherapy in 92 % of cases. The phenomenon of rituximab-induced elimination of serum antineuronal autoantibodies is associated with the effect of neuroprotection, which was confirmed by the normalization of previously elevated serum concentrations of laboratory biomarkers of NSE cerebral damage (OR = 17.875; 95% CI = 4.738–67.436 at Ab to GADA and 41.800; 7.257–240.778 at Ab to potassium channels) and S-100 protein (9.750; 2.707–35.113 and 18.333; 3.462–97.083, respectively). In parallel, there was a progressive improvement in all indicators of the mental status of children with ASD on the ABC scale with a latency period of about 2 months (p < 0.05: Z < Z0.05). Conclusions. Immunotherapy with rituximab by eliminating the serological signs of antineuronal autoimmunity realizes the effect of neuroprotection, reducing the severity of all major clinical signs of ASD in children with HFM.
New opportunities in the treatment of patients with chronic brain ischemia
Authors: Mishchenko V.M. , Zabrodina L.P. , Mishchenko T.S. , Bovt Yu.V.
Published: October 2021

The study was aimed to evaluate the clinical efficacy of Hericium erinaceus extract (Cebrofit) in combination with vinpocetine compared to vinpocetine monotherapy in patients with chronic cerebral ischemia. Two groups of patients were identified — the basic and control, which included 160 patients with stage I and II dyscirculatory encephalopathy aged 30 to 80 years. All subjects underwent basic therapy, during which for 3 months patients of the basic group took Cebrofit 1 capsule 150 mg twice a day and vinpocetine (Vicebrol) 1 tablet 5 mg three times a day, and patients of the control group used only vinpocetine according to the scheme described above. Based on a comprehensive study, it was found that the use of Cebrofit in combination with vinpocetine compared to vinpocetine monotherapy resulted in accelerated regression of subjective and objective manifestations of chronic brain ischemia with an advantage in patients with stage I dyscirculatory encephalopathy. In patients with stage I dyscirculatory encephalopathy, the use of Cebrofit in combination with vinpocetine produced a pronounced neuroprotective effect, which manifested in a significant improvement in general condition, a decrease in the severity of neurological symptoms, a decrease in the manifestations of asthenia and anxiety after 28 days of therapy, and a significant increase in cognitive performance after 7 days of therapy, while maintaining this positive trend until the end of the course of treatment. In patients with stage II dyscirculatory encephalopathy under the influence of Cebrofit in combination with vinpocetine, positive differences in the form of a decrease in the severity of clinical and neurological symptoms, manifestations of asthenia, anxiety, and depression, as well as improvement in cognitive functions were recorded after 84 days of treatment, which allows recommending the use of these schemes in clinical practice.
FEMSLASH FANFICTION AND LESBIANISM: EFFORTS TO EMPOWER AND EXPRESS ASIAN AMERICAN WOMAN SEXUALITY
Authors: Kartika Tyas Willy , C.S.T Maria Elfrieda
Published: October 2021

The existence of fan fiction nowadays shows more progressive development especially in this digital era when people does not only use internet for communicating and socializing across time and space but they also show their creativity, one of them is by writing a fan fiction. By writing fan fiction in online platforms, people get the opportunity to express their interests and their identities. This opportunity is also obtained by minority groups such as LGBTQ+ where they can express their identity through fan fiction. LGBTQ+ community utilizes online platform as the tool that brings benefit for them. In this case, writing fan fiction in online platforms allows people to create the preferable representation of minority groups and empower them as the part of LGBTQ+ community. This phenomenon can be seen through a website named Asianfanfics.com which shows an increasing number of fan fictions especially the ones with lesbian related tags such as girl x girl, lesbian, and femslash. Particularly, through the femslash subgenre, people use fan fiction to question the heteronormativity. Regarding to this phenomenon, an interview was conducted by choosing three Asian American fan fiction writers from Asianfanfics.com as the interviewees. Furthermore, by using gender theory and intersectionality, this article focuses on how fan fiction becomes a safe space to express their sexual identities and how lesbian relationship is viewed by Asian families.
Schizophrenia, Maslow and Coping Strategies
Authors: - Anon
Published: October 2021

None
Metodología basada en un algoritmo genético para programar la producción de una empresa del sector textil
Authors: Espitia Méndez Julieth Andrea , Mendoza Rojas Germán Leonardo
Published: October 2021

En este trabajo se presenta la aplicación de una metodología basada en algoritmos genéticos, dirigida a la minimización del makespan (C_max) y cantidad de trabajos tardíos (U(γ)) en un ambiente flow shop híbrido flexible perteneciente a la industria textil. La metodología fue evaluada en escenarios de producción reales de la empresa objeto de estudio. La población inicial se generó a partir de una lógica de asignación basada en las restricciones del sistema productivo de la empresa. Los resultados de la metodología fueron comparados con datos reales de la empresa, dando como resultado un mejor desempeño en las dos funciones objetivo (FOB).
Gripes asesinas y el reinado del virus corona
Authors: Rodríguez Ceberio Marcelo
Published: October 2021

Este es el segundo texto de una serie de dos, que desarrollan la historia de las más grandes epidemias y pandemias del mundo. En el primero se describieron y analizaron las pandemias precedentes a la COVID-19: las pestes que asolaron el mundo greco-romano y otras enfermedades infectocontagiosas hasta llegar a la peste rosa, como fue llamado el virus del sida. El presente desarrollo se inicia con una serie de gripes mortíferas que terminan en la actualidad con la generación de los virus de la familia corona. Se describen las características de cada enfermedad y los desórdenes emocionales, económicos, psicológicos, entre otros, que se desataron en cada contexto donde proliferó el virus.
Reaching the limits of co-creation in citizen science — exemplified by the linguistic citizen humanities project ‘On everyone’s mind and lips — German in Austria’
Authors: Heinisch Barbara
Published: October 2021

Co-creation aims at integrating citizens in the entire research process. The citizen linguistics project German in Austria tests this approach in the humanities based on the assumption that language is ubiquitous. The project combines different forms of public participation, including a co-created format, where citizens can raise (and answer) research questions about the German language in Austria and a linguistic treasure hunt, where citizens collect and analyze data on linguistic landscapes. However, co-creation was hard to implement. Despite a high number of participants, their willingness to contribute to more than one research step was low.
Citizen science and crowdsourcing in the field of marine scientific research — the MaDCrow project
Authors: Diviacco Paolo , Nadali Antonio , Nolich Massimiliano , Molinaro Andrea , Iurcev Massimiliano , Carbajales Rodrigo , Busato Alessandro , Pavan Alessandro , Grio Lorenzo , Malfatti Francesca
Published: October 2021

Marine research is as important as very demanding since it requires expensive infrastructures and resources. Scientific institutions, on the contrary, have very limited funding so that the seas remain, still, mostly unexplored. Another serious concern is that society at large often resonates with fake news, while scientists sometimes tend to bias research with their backgrounds and paradigms. We think that all these issues can be addressed opening the process of knowledge building to the questions and needs of stakeholders and laypeople. The MaDCrow project proposed and tested several paths to attain these goals.
Presentación
Authors: Prado Pamela
Published: October 2021

Presentación del número
CONSTITUCIÓN, FEMINISMO Y DIVERSIDAD. EL TRILEMA DEL FEMINISMO CONSTITUCIONAL
Authors: De Lora del Toro PABLO
Published: October 2021

Este trabajo tiene por objeto analizar qué quiere decir que una Constitución – o para el caso, una política pública o una pieza legislativa- adopte una “perspectiva de género”; qué pueda querer decir que una Constitución es “feminista” y si tal cosa es deseable, y qué razones pueden justificar que la composición de la Convención Constitucional sea paritaria entre hombres y mujeres.
LA RAZONABILIDAD EN LA ESCENA JUDICIAL: HACIA UN “HÉRCULES” TERRENAL
Authors: Gatti Franco
Published: October 2021

El presente trabajo tiene por objeto discutir las implicancias que adquiere la noción de razonabilidad en el derecho, deteniéndose especialmente en los modos en que impacta en la configuración de un modelo de sujeto de derecho. A partir de este análisis, y considerando el carácter “poroso” del concepto estudiado, se abordará el rol que desempeña la judicatura para atribuirle una significación. Específicamente, la investigación profundizará en las diversas formas en que los tribunales han utilizado la categoría de la “razonabilidad” para responder a circunstancias imprevistas por la legislación y que reeditan el histórico debate entre la preservación de la estabilidad jurídica y la necesaria flexibilidad de las decisiones judiciales.
LA INTRANSMISIBILIDAD DE LA OBLIGACIÓN ALIMENTICIA.
Authors: Sabioncello Muriel
Published: October 2021

su carácter personalísimo, es intransmisible. El problema surge delhecho que, si bien el Código Civil en su artículo 334 expresa claramenteque el derecho de alimentos no puede transmitirse por causa de muerte,no existe una norma semejante que resuelva si la obligación alimenticiaes o no transmisible, por lo que es necesario que esta cuestión searesuelta, toda vez que la determinación de la naturaleza transmisibleo intransmisible de la obligación alimenticia incide directamente en lasucesión del obligado a otorgar alimentos por una sentencia judicial o unequivalente jurisdiccional.
Normas editoriales
Authors: Prado Pamela
Published: October 2021

Normas editoriales
Should National Institute for Clinical Excellence (NICE) Guidelines Remove Urine Cytology as a Suggested Adjunct in Suspected Bladder Cancer (haematuria) Investigations?
Authors: Moore Madeline , Robinson Andrew , Kitchen Mark O , Gommersall Lyndon
Published: October 2021

Background

Despite National Institute for Clinical Excellence (NICE) guidelines suggesting the use of urine cytology (UC) for the diagnosis of bladder cancer, its use is variable. Reasons for this include sub-optimal sensitivity, financial cost, availability of alternative tests, and uncertainty over interpretation of results. Anecdotally, however, suspicious or malignant UC when other investigations are normal, occasionally leads to a cancer diagnosis. Therefore, we retrospectively assessed a cohort of our haematuria patients to determine the value of UC in cancer diagnosis and the clinical significance of atypical UC (graded as C3).

Patients and methods

We identified 3018 patients with haematuria referred on the suspected cancer pathway (“two-week wait”) in 2015. We retrospectively analysed clinical, demographic, and follow-up/outcome data in a random cohort of 500 cases.

Results

Median follow up was 58 months. Urological malignancy was diagnosed in 61/500 patients; all were identified by cystoscopy or imaging, i.e., irrespective of UC result. No cases of atypical UC re-presented with a ‘missed’ cancer diagnosis within the five-year follow-up period. However, suspicious and malignant cytology was associated with high-grade/aggressive tumours and subsequent tumour recurrence.

Conclusion

Urine cytology did not identify any cancers that were not already found by imaging or cystoscopy. Atypical UC in the presence of negative haematuria investigations does not appear to be associated with malignancy, and therefore should not alter patient management nor prompt further investigation. Suspicious and malignant UC was associated with higher risk cancers and could therefore be used to prioritise waiting lists for transurethral resection of bladder tumour (TURBT), however, it is unclear whether this might benefit patient outcomes. We conclude therefore that UC has no role in haematuria investigations.
At the Origins of the Dialogue of Epic Novels in the Journal Russian Bulletin (I. S. Turgenev and B. M. Markevich)
Authors: Lebedev Yuriy V.
Published: October 2021

The article examines the emergence of personal and then creative ties between I. S. Turgenev and B. M. Markevich. It is proved that the novels of Markevich and other members of the “constellation of Moscow writers”, employees of the Russian Bulletin, were created with an attitude towards artistic polemic. The article examines connections and confrontations in the worldview of Turgenev and Markevich, who shared the ideological guidelines of the editor of the “Russian Bulletin” M. N. Katkov. Markevich advocated the state integrity of the country, in addition to Turgenev’s “nihilists” and “superfluous people”, he chose patriotic nobles as literary heroes. In the novel Types of the Past, published in the Russian Bulletin four months after the publication of the novel Smoke, Markevich contrasted Irina and Litvinov with “a virtuous matron” and “exemplary citizens”. Markevich argues with Turgenev’s cult of love as a spontaneous passion, defending Orthodox Christian values. Turgenev’s response to this novel is lost, but Markevich’s reply letter shows that Turgenev subjected him to severe criticism. In the novel Virgin Soil in the person of Nezhdanov, Turgenev gave a polemical answer to Markevich, resolving this conflict in his own way in favor of the hero’s political convictions.
O LAZER NOS CURRÍCULOS DOS CURSOS DE EDUCAÇÃO FÍSICA: DIVERSIDADES E TENDÊNCIAS
Authors: Cavalcante Fernando Resende , Lazzarotti Filho Ari
Published: October 2021

O objetivo deste artigo foi caracterizar as disciplinas relacionadas ao lazer nos currículos dos cursos de Educação Física do Brasil. Foi utilizada metodologia mista e a técnica Análise Categorial. Como conclusões o lazer parece ocupar pouco espaço na quantidade de disciplinas e no tempo dedicado a elas. A localização no fluxo curricular é diversa, entretanto no bacharelado as disciplinas tendem a estar na primeira metade da formação. As ementas diversificam suas relações com outros temas, todavia, se destacam a recreação, as políticas públicas, a educação, a cultura e o esporte. Nos enfoques há preponderância dos teórico-conceituais em detrimento dos instrumentais. As bibliografias são diversificadas e identifica-se uma ampla presença dos livros, com a valorização de obras introdutórias e conceituais. O autor mais referenciado é Nelson Carvalho Marcellino.
Diagnóstico de linfangioma cavernoso de face em paciente adulto: relato de caso clínico
Authors: Puricelli Edela , Romanini Juliana , Munerato Júlio César , Oliveira Márcia Gaiger de
Published: October 2021

The authors present a case of a 18 (eighteen) years old male patient, presenting a recurrent painless tumour on the left side of his face, growing both intra and extraorally- It caused progressive limitation of mandibular mobilitv. Histopathological result of cavernous lymphangioma differed from the previous findings seen on magnetic resonance imaging.
Epitope mapping of African swine fever virus (ASFV) structural protein p30
Authors: zhang yao , Wang Aiping , Zhou Jingming , Liu Hongliang , Chen Yumei , Ding Peiyang , Zhu Xifang , Liang Chao , Qi Yanhua , Zhang Gaiping
Published: October 2021

Since African swine fever (ASF) was first reported in 1921, it has
brought huge economic losses to the world pig industry. No vaccine or
therapy is available. Rapid and effective diagnostics are key steps in
managing ASF. We generated three monoclonal antibodies (mAbs) against
the African swine fever virus (ASFV) phosphoprotein p30 and designated
these as 7D2, 8C8 and 2F6. Epitope mapping revealed that mAb 7D2
recognized VFHAG SLYNW of p30,
and mAb 8C8 and 2F6 recognized MDFIL NISMK MEVIF
KTDLR of p30. Furthermore, epitope
MDFIL NISMK MEVIF KTDLR and
VFHAG SLYNW could be well
recognized by ASFV-positive sera from natural infected pigs, suggesting
that they were natural linear B-cell epitope. Conservation analysis
indicated that epitope MDFIL NISMK MEVIF KTDLR
and VFHAG SLYNW
were highly conserved among the different strains
of ASFV. This is the first research to characterize specific mAbs
against p30 protein. These findings may facilitate further understanding
the function of p30 protein and development of diagnostic tools.
Computer-Aided Process Intensification of Natural gas to Methanol Process
Authors: Monjur Mohammed Sadaf , Hasan M. M. Faruque
Published: October 2021

The recent revolution in shale gas has presented opportunities for
distributed manufacturing of key commodity chemicals, such as methanol,
from methane. However, the conventional methane-to-methanol process is
energy intensive which negatively affects the profitability and
sustainability. We report an intensified process configuration that is
both economically attractive and environmentally sustainable. This
flowsheet is systematically discovered using the building block-based
representation and optimization methodology. The new process
configuration utilizes membrane-assisted reactive separations and can
have as much as 190% higher total annual profit compared to a
conventional configuration. Additionally, it has 57% less
CO2-equivalent greenhouse gas (GHG) emission. Such drastic improvement
highlights the advantages of building block-based computer-aided process
intensification method.
Avaliação de vida útil econômica do ativo imobilizado do setor avícola
Authors: Da Silva Andréa Soares , Roveri Ricardo Bangni , Gonzales Alexandre , Marion José Carlos
Published: October 2021

A contabilidade brasileira iniciou seu processo de convergência aos padrões internacionais de contabilidade com a criação do Comitê de Pronunciamentos Contábeis, que é o órgão responsável pela emissão e estudo dos pronunciamentos que são balizadores do processo. O processo inicial se deu pela lei 11.638/2007, e em decorrência das alterações introduzidas por ela, o Comitê de Pronunciamentos Contábeis emitiu o CPC 27, que trata especificamente do assunto Ativo Imobilizado, no qual um dos tópicos é sobre avaliação da vida útil econômica para fins de depreciação. O presente artigo buscou responder a seguinte pergunta: as empresas do setor de avicultura no Brasil, estão aplicando o conteúdo do CPC 27 – Ativo Imobilizado, a respeito do conceito de vida útil econômica para fins de cálculo da depreciação? A pesquisa consistiu em conectar a prática, utilizando os questionários respondidos pelas empresas do setor avícola, avaliando o objetivo da aplicação do conceito de vida útil econômica para fins de depreciação, atrelado ao uso do ativo em função da sua condição de geração de benefícios econômicos para entidade que os controla, e utilizando também testes estatísticos para comparação das médias. O questionário apresentou indagações, a fim de identificar aplicação dos conceitos, vida útil média por subgrupos de ativo imobilizado, relevância do custo x benefício de sua aplicação, e impacto nas demonstrações. Apesar de mais de dois terços considerarem que a avaliação da vida útil econômica para fins de cálculo da depreciação tem efeito relevante nas demonstrações financeiras, sua aplicação prática não mostrou o mesmo nível.
Histopathological and apoptotic examination of zebrafish (Danio rerio) gonads exposed to triclosan
Authors: Akbulut Cansu
Published: October 2021

Triclosan, produced as a broad-spectrum antibiotic in the early 1960s, is generally used as a preservative in personal care products, fabrics, plastic products such as kitchenware and toys. As a result of the high demand for triclosan, this chemical threatens the aquatic ecosystem by contaminating wastewater sources. Environmental pollutants affect the reproductive potential of fish, one of the most critical aquatic organisms. This study aimed to investigate the histopathological and apoptotic effects of triclosan in zebrafish gonads. Fish were exposed to sublethal concentrations of triclosan for 5 days, and general histological methods were applied. Histological sections were examined under a light microscope after staining with hematoxylin and eosin and toluidine blue. Triclosan exposure caused deterioration in ovarian tissue, such as shrinkage in the ooplasm, accumulation of proteinaceous fluid in the interstitial tissue, morphological changes of oocyte and the zona radiata. In testicular tissue, triclosan exposure caused fusion in seminiferous tubules, hypertrophy in spermatogenic and Leydig cells, edema in seminiferous tubules, and karyorrhexis in spermatogenic cells. The TUNEL assay was used for the determination of apoptotic cells. Brown-colored apoptotic cells were visualized under the light microscope. TUNEL positive cells were observed in all exposure groups. Triclosan administration was found to cause apoptosis in zebrafish gonads. These findings indicate that triclosan potentially affects fish reproduction, and that its judicious disposal is essential for protecting the environment and maintaining the reproductive potential of fish.
Genetic variability and selection criteria of some sesame genotypes for their agronomic traits and seed quality
Authors: Abdelsatar Mohamed , Eraky Hania
Published: October 2021

The identification of genetic variation, mean performance, and selection
criteria for twelve sesame genotypes is required for the genetic enhancement
of agronomic traits and seed quality. Thus, using a randomized complete
block design with three replications, these genotypes were evaluated in a
field trial at the Kafr-El-Hamam Agricultural Research Station, Agricultural
Research Center, Sharkia Governorate, Egypt, and laboratory experiments at
the Seed Technology Research Department, ARC, Giza, Egypt, during the two
consecutive seasons of 2018 and 2019. For earliness in flowering, N.A.130
and Shandweel3 were the most promising sesame genotypes, while N.A.114 and
RH1F3 had the heaviest weight of seed plant-1 and one or more yield-related
traits, and NA114, Shandweel3, and Zahar12 had the best seed quality traits.
Furthermore, Shandweel3 and M1A12 had the highest proportion of seed oil,
Shandweel3 and Zahar12 had the largest amount of oleic acid, N.A.114 and
RH1F3 had the highest content of linoleic acid, and Zahar12 and N.A.114 had
the highest proportion of linolenic acid. Seed weight plant-1 can be
improved through selecting genotypes having the lengthiest fruiting zone,
more branches and capsules, and the high electrical values of seed
conductivity, accelerated aging germination as demonstrated by selection
criteria. Moreover, the oleic acid proportion had the greatest direct and
indirect effect on seed oil content, demonstrating its relevance as sesame
oil quality selection criteria.
Comparative study on the elemental composition of different parts of cultivated Physalis alkekengi (Solanaceae)
Authors: Jovanovic Snezana , Mrmosanin Jelena , Zlatkovic Bojan , Djukic Milos , Pavlovic Aleksandra , Stojanovic Gordana
Published: October 2021

This study aimed at analyzing and comparing the elemental composition of different parts of cultivated Physalis alkekengi (ljoskavac): rhizome with roots, stem with leaves, fruit, and inflated calyx. The contents of twenty- -one macro- and micro-elements were determined by inductively coupled plasma optical emission spectrometry (ICP-OES). In addition, the patterns of the distributions of both macro- and micro-elements were subjected to AHC analysis which gave different grouping of samples in sub-clusters. Generally, potassium, calcium, iron, and aluminum were the most abundant elements, but with different distribution in examined parts. High contents of iron and aluminum were detected in a stem with leaves, followed with samples of rhizome with roots and calyx, while potassium dominates in samples of calyx and stem with leaves. Edible fruits did not contain potentially toxic metals in concentration higher than permissible limits, wherein the lowest contents of lead and aluminum were detected; cadmium was under limit of quantification. Arsenic, mercury, and thallium were below the method detection limit.
Hume’s and Kant’s understanding of epistemic normativity
Authors: Nurkic Petar
Published: October 2021

Question (d) how do we form beliefs?, implies descriptive answers. On the
other hand, the question (n) how should we form beliefs?, implies normative
answers. Can we provide answers to (n) questions without answering (d)
questions? This (n) - (d) relation can be characterized as epistemic
normativity. Hume and Kant provide answers to both questions. Hume is more
inclined to psychologize these answers through an empirical approach to
questions related to beliefs. While Kant is more inclined to consider a
priori conditions of our reasoning. Through general rules and epistemic
maxims, Hume and Kant provide normative guidelines in accordance which we
should form beliefs. However, in order to be able to talk about normativity,
at all, we need to answer questions related to doxastic voluntarism. For
Kant, the question of freedom is, to some extent, an obvious precondition
for his critiques (especially of the practical mind). While with Hume,
precisely because of his empirical approach to beliefs and desires, the
matter is more obscure, and it seems as if Hume advocates doxastic
involuntarism. In this paper, I will try to present the similarities between
Hume and Kant in terms of epistemic normativity. Where it seems as if their
views are incompatible, I will try to examine why this is the case. I will
focus on Hume?s Treatise of Human Nature and Kant?s Second Analogy. In the
end, I will present a couple of thought experiments and try to ?test? Hume
and Kant. If I manage to confirm the initial hypotheses, then this paper
will be a successful epistemic endeavor. However, if I fail to find the
expected similarities between Hume?s and Kant?s understanding of epistemic
normativity, then this work can be characterized as a historical approach to
the normative framework of ?dogmatic slumber?.
The basic problems of phenomenology and being and time: The issue of research methods and ontological difference
Authors: Banovic Nebojsa
Published: October 2021

The piece considers the relation and connection existing between Heidegger?s
main work Being and Time and The Basic Problems of Phenomenology (1927),
above all when considering their complementary regarding methods of research
confirmed as hermaneutic-phenomenological. This attempt to clear the
mentioned relations is intended to show how methodical approaches presented
in both Heidegger?s works are aimed to reveal ontological difference, which
as a sense of being contain the key of understanding his philosophy.
The Application of Mesoporous ZSM-5 Zeolite in the ULSD Catalysts
Authors: L Liu
Published: October 2021

The mesoporous ZSM-5 zeolite containing MoCoP/Al2O3 catalyst (C12-ZSM5) with the mixture of Al2O3 and mesoporous ZSM- 5 zeolite as carrier was synthesized. The catalytic performance of C12-ZSM5 catalyst was evaluated by the hydrodesulfurization (HDS) of different diesel feedstock. The carriers and catalysts were characterized by N2 adsorption-desorption, pyridine-FTIR, X-ray diffraction (XRD) and CO in-situ FTIR (CO-FTIR) techniques. Results showed that mesoporous ZSM-5 can improve the acidity of the catalyst and increase the number of MoCoS active phases. The C12-ZSM5 catalyst had low HDS and HDN activity, because the acidic sites of mesoporous ZSM-5 were easily occupied by nitrogen compounds. The HDS activity of C12-ZSM5 catalyst was fully exploited by using graded packing technology, the sulfur content of product oil was 5.9 ng/μL. The relative HDS activity of C12-ZSM5 catalyst is 1.47 times that of FHUDS-8 catalyst.
Deregulation of Diesel and Petrol Pricing in Ghana: Perspectives of Commercial Drivers
Authors: E Broni Bediako
Published: October 2021

The process to deregulate the pricing of petroleum products kept evolving until July 2015 where fuel prices were completely deregulated, and managed by Bulk Distribution Companies (BDCs) and Oil Marketing Companies (OMCs) under supervision of the National Petroleum Authority (NPA). This phase of the deregulation policy ended the subsidy regime. Deregulation policy was implemented to help stabilise price hikes. As a land mark policy, deregulation has implications. This research assessed perspectives of commercial drivers on deregulation of diesel and petrol pricing in Ghana using Tarkwa as a test case. The methods employed include field visits to lorry stations in Tarkwa; interviews and questionnaire administration; and statistical analysis of data. The study revealed that majority of commercial drivers are aware of the implementation of the deregulation policy in Ghana but do not understand its effects. All the commercial drivers revealed that there are different prices of diesel and petrol at pump stations. Majority were of the view that their choice of a pump station depends on both the price and quality of the fuel, and the proximity of the pump station to their operations. All commercial drivers asserted that the deregulation policy has negatively affected their business. It is therefore recommended that the NPA should insist on price reduction nationwide when prices of fuels are reviewed downwards and also ensure that the right information is efficiently communicated to consumers of petrol and diesel in Ghana especially commercial drivers to minimise the risks of anxiety.
Effect of the Physicochemical Properties of Soils on Generalized and Localized Corrosion Rate of API X52 and X60 Pipeline Steels
Authors: A Contreras
Published: October 2021

This work analyzed physicochemical properties of different types of soils on the generalized and localized corrosion rate in two steels (X52 and X60) most used in pipeline transportation of hydrocarbons. The physicochemical properties such moisture content, pH, resistivity and redox potential, which influence the corrosion rate of the pipelines were analyzed. Soils from three different sites in the south of México were obtained. Soils were sampled approximately 1.5 m deep, close to pipeline. From the analysis of generalized corrosion results taking into account the type of soil, it was observed that the most corrosive soil for the two steels was soil-3, generating corrosion rates of 0.119 and 0.097 mm/year, for the X52 and X60 steels respectively, after a period of 6 months. It is important to note that the maximum generalized corrosion rate was obtained after 1 month of exposure of the steels, generating corrosion rates of 0.177 and 0.162 mm/year, for the X52 and X60 steels respectively. In similar way, the localized corrosion rates for the both steels were higher when steels are exposed to Soil-3, generating corrosion rates of 1.1 and 0.45 mm/year, for X52 and X60 steel respectively, after a period of 6 months. In general it was observed that X60 steel presents greater resistance to pitting corrosion rate (in Soil-3), which can be attributed to its more homogeneous microstructure, fine grain size, and its chemical composition that presents elements such as Cr and Ni in greater quantity than X52 steel, which improve the corrosion resistance. However, depending on the type of soil the corrosion resistance behavior of each steel is different. From the analysis of various equations fits, it was determined that the potential equation is the one that gives the best fit for all cases.
A New Inhibitor to Prevent Hydrate Formation
Authors: M Bazvand
Published: October 2021

Due to the growing demand for energy as well as the depletion of shallow land reservoirs, it sounds more important to utilize deep sea reservoirs. Due to their special conditions, drilling and production of these reservoirs face more problems. The science that helps us avoiding problems during operation is called flow assurance. One of the important issues in flow assurance is to prevent formation of gas hydrates. One of gas hydrates preventing methods is to use of inhibitors. Using of inhibitors is a cost- effective and eco-friendly method; so, it is used more nowadays. This paper introduces a new hydrate inhibitor that has been developed from the modification of one of the most widely used inhibitors present in the industry, Poly Vinyl Pyrrolidone, to improve its efficiency. The main structure of the paper is about what is the gas hydrate and its prevention methods. Finally, compare different inhibitors with new one. The results show that hydrate formation time for all polymers is approximately the same, while a half of new inhibitor in compare with amount of others inhibitors causes the same results. This matter shows a double efficiency, and this means a saving of double Polymer consumption.
Thermodynamic Aspects of pH and Wettability Changes in Low Salinity Water Flooding Oil Recovery
Authors: A Miadonye
Published: October 2021

Low salinity water flooding has for decades emerged as a technically and economically viable enhanced oil recovery scheme due to its environmentally attractive nature. In the literature, several reasons have been proposed for its immense success, some of which have been experimentally proven. Among the reasons given, wettability and pH increase have been greatly highlighted. In this paper, we have developed a pH and salinity dependent Gibbs free energy of adsorption model, using established thermodynamic concepts to prove the viability of hydrogen ions adsorption which can lead to pH and wettability increase. Accordingly, we have shown based on theoretical calculations that as salinity decreases, adsorption free energy for hydrogen ions decreases, leading to pH decrease at lower salinities. Our theoretical calculations also agree with optimum salinity ranges reported in the literature.
A Review of Industrial Paraffin Production Technologies Based on Recent Developments
Authors: M Hassanpour
Published: October 2021

Lubrication or tribology, which is the science of facilitating the relative motion of surfaces in contact with each other, is one of the most important disciplines in science, technical knowledge, and engineering operations today. Regarding the vast application of Industrial Paraffin (IP) in daily life and the existence of numerous oil wells, the current review discussed IP production technologies and applications of IP in many human demands in the framework of a project and its public involvements. It was summarized the recent technologies posed in IP production from valid and available databases to demystify the existing alternatives. The information of assessed projects in the Environmental Impact Assessment (EIA) plan was offered to access the framework of the initial assessment of the evaluator team in the screening step of project identification. The review of developed technologies surged the interests of decision-maker for pushing the industrial projects towards decision theory to make the matrix of data for further assessment depend on the quality and quantity of the requested product. The conclusion of the current review ended up attracting decision-maker opinion to mitigate the hazardous and health effects of introduced technologies by selecting the best alternative in IP production operation.
Synthesis of Bio-gas Using Squander Cooking Oil
Authors: JM Bahig
Published: October 2021

The point of this examination is to evaluate the performance of both catalytic and thermal cracking processes in the thermochemical conversion of squander cooking oil into biofuel and investigate the impact of ZSM-5 impetus and breaking reactor temperature to items yield, biofuel caloric substance and synthetic arrangement. Several parameters might affect process performance which resulted in different product’s yield and specification. Cracking temperature variation gave appreciable effect on yield and product’s caloric values.
Using Bayesian Networks for Quantifying Domino Effect Probability in a Hydrocarbon Processing Area
Authors: JA Duenas  Santana
Published: October 2021

Accidents in process industries include fires, explosions, or toxic releases depending on the spilled material properties and ignition sources. One of the worst phenomena that may occur is the called domino effect. This triggers serious consequences on the people, the environment, and the economy. That is why the European Commission defined the domino effect prediction as a mandatory challenge for the years ahead. The quantification of the domino effect probability is a complex task due to the multiple and synergic effects among all accidents that should be included in the analysis. However, these techniques could be integrated with others in order to represent the domino effect occurrence reliably. In this matter, artificial intelligence plays a vital role. Bayesian networks, as one of the artificial intelligence nets, have been widely applied for domino effect likelihood determination. This research aims to provide a guide for quantifying domino effect probability using Bayesian networks in a hydrocarbon processing area. For this purpose, a four-step model is proposed integrating some classical risk analysis techniques with Bayesian networks. Moreover, this methodology is applied to an actual hydrocarbon storage and processing facility. After that, the joint probability can reach 9.37% for the process unit tank 703 which storages naphtha. Hence, safety management plans must be improved in this area for reducing this actual risk level. Finally, this research demonstrates how Artificial intelligence techniques should be integrated with classical ones in order to get more reliable results.
Korona-altistusten jäljittämiseen tarvitaan uusia ratkaisuja
Authors: Haatainen Kaisa , Julkunen Sonja , Kaskenaho Viivi , Kervinen Marjo
Published: October 2021

Kontaktien jäljittäminen on oleellinen osa infektioiden hallintaa ja ehkäisyä. Ihmistyönä toteutettavan kontaktien jäljittämisen rinnalle tarvitaan uusia aikaa säästäviä sekä kustannustehokkaita ratkaisuja, jotka mahdollistavat myös nykyaikaisen teknologian täyden hyödyntämisen.  Radiotaajuuksilla toimivan etätunnistusteknologian (RFID) käytöstä on jo lupaavia tuloksia, mutta soveltaminen terveydenhuoltoon on hidasta.

 

Koronaltistusten jäljitysprosessi on aikaa vievää sekä sen saavuttamat tulokset epävarmat, koska kontaktien kartoitus on muistinvaraista. Kun COVID -19 testi on henkilökunnan jäsenellä positiivinen, kontaktien jäljittäminen tapahtuu kyselemällä ja kartoittamalla altistuneet työntekijät yksikön esihenkilön tai vastaavan hoitajan toimesta. Kontaktien kartoitus ei ole systemaattista, se on aikaa vievää eivätkä tulokset ole luotettavia. Mikäli työyksikössä on joukkoaltistuminen ja/tai altistuminen koskee useita työyhteisön jäseniä, prosessi on huomattavan monimutkainen ja työläs. On kehitettävä uusia ratkaisuja, joiden avulla voidaan altistuneet jäljittää nopeammin ja varmemmin.
1st Kyiv Round Table Dedicated to TMJ Fractures Treatment (1st Kyiv TMJ Round Table): 27, 28 December 2018 – Kyiv – Ukraine
Authors: Pavlenko Ruslan , Romanova Anna
Published: October 2021

1st Kyiv Round Table (RT) dedicated to temporomandibular joint (TMJ) fractures treatment was extremely successful. And it`s symbolic that initiative of Professor Kopchak, Associate Professor Chepurnii, and Professor Ankin to establish TMJ RT was supported by the world titan in the diagnostics and treatment of TMJ fractures–Dr. Andreas Neff (Marburg, Germany).
Andreas Neff, MD, DMD, PhD, FEBOMS, Univ. Prof. is a Head and Chairman in the Department of Oral and Craniomaxillofacial Surgery, Oral Surgery and Implantology UKGM GmbH, University Hospital of Marburg & Medical Faculty, Philipps University Marburg [1].
Pemodelan Vector Autoregressive (Var) untuk Data Jumlah Perceraian di Kota Pekanbaru
Authors: Desvina Ari Pani
Published: October 2021

Perceraian merupakan terputusnya hubungan antara suami istri akibat dari kegagalan pasangan suami istri dalam menjalani peran masing-masing. Maraknya fenomena perceraian yang terjadi bisa disebabkan oleh beberapa faktor seperti faktor ekonomi, tidak harmonis dan tidak bertanggung jawab. Model Vector Autoregressive (VAR) merupakan salah satu model yang digunakan untuk menentukan peramalan dengan beberapa variabel dan berguna untuk  melihat keterkaitan hubungan antar variabel. Tujuan penelitian ini yaitu untuk menentukan peramalan jumlah perceraian di Kota Pekanbaru dengan menggunakan model Vector Autoregressive (VAR). Data yang digunakan dalam penelitian ini adalah data time series yaitu data jumlah perceraian, faktor ekonomi, tidak harmonis dan tidak bertanggung jawab di Kota Pekanbaru mulai Januari 2014 sampai Desember 2018. Hasil pembahasan yang diperoleh menunjukkan bahwa model VAR(2) adalah model yang sesuai untuk meramalkan jumlah perceraian di Kota Pekanbaru pada waktu yang akan datang. Berdasarkan hasil uji kausalitas Granger menunjukkan bahwa perceraian mempengaruhi tidak harmonis, tidak harmonis mempengaruhi ekonomi, dan tidak harmonis mempengaruhi tidak bertanggung jawab. Sedangkan hasil peramalan jumlah perceraian di Kota Pekanbaru  untuk Januari 2019 sampai Desember 2020 menunjukkan terjadinya peningkatan yang tidak berbeda jauh dari bulan sebelumnya, dengan nilai akurasi peramalannya menggunakan MAPE adalah 47,76 %.
Distance educational technologies as a facilitator of students’ cognitive flexibility: risks and prospects
Authors: Nechitailo Iryna Sergiivna , Dymar Nataliia Mykchaylivna , Biriukova Maryna Vasilivna , Liashenko Nataliia Oleksandrivna , Zverko Tamara Vasylivna
Published: October 2021

The article is devoted to the analysis of training methods in higher educational institutions, the comparison of the main characteristics of the educational process in institutions of full-time and distance learning, their disadvantages in modern conditions are identified, the main advantages of distance learning, compared to the ways of providing and processing information, the interaction of teachers and students of different forms of education, the application of methods of facilitation and development of cognitive flexibility in modern distance education are considered. The directions of distance learning influence on the process of formation of students' creativity and freedom of opinions, ability to search for solutions, and aspiration to self-education are described. The relationship between the methods of facilitation and formation of cognitive flexibility in students' education is revealed. The main directions of self-improvement and peculiar characteristics of teachers who can perform the functions of a facilitator of the educational process are described. The influence of the teacher-facilitator and distance education methods directly as a facilitator of the process of formation of cognitive flexibility of students is considered.
CAN EFL LEARNERS' LEARNING STYLES IMPACT THEIR PERFORMANCE ON WRITING SKILL UNDER DIRECT AND INDIRECT CORRECTIVE FEEDBACKS?
Authors: Maghsoudi Mojtaba , Saeedi Sahar
Published: October 2021

This study presents the findings of an investigation of the impact of teacher error corrective feedback on 180 field-dependent/ field-independent (FD/FI) male and female pre-intermediate and advanced Iranian EFL learners writing skill. The participants were separated into two experimental groups and one control group and were asked to write three paragraphs of about 100-150 words around three different topics, each in odd days of a week; then they received direct (in experimental group 1), indirect (in experimental group 2) and no correction feedback (in control group). The results based on Mean Scores, Standard Deviation, Multivariate Analyses and 1-way ANOVA showed that there was not any significant difference between the FD/FI learners' writing skill scores who had received corrective feedback on their errors; however, as indicated by the second finding of the present study it would be better to feedback field-dependent/-independent EFL learners indirectly. It was also indicated that, learners' learning styles had made a significant change in their writing skill scores.
WOLLSTONECRAFT AND FRIEDAN�S THEORIES HIGHLIGHT THE WOMEN STRUGGLES IN JULIUS CAESAR
Authors: Dukut Ekawati Marhaenny , Malik Farhana
Published: October 2021

For centuries, women have been struggling to establish their place in the society and fight for their rights as becoming an equal to men. This article, presents an analysis on the female characters - Portia and Calpurnia of Rome, in Julius Caesar. The play was written by William Shakespeare who based his story on the historical events of Ancient Rome. Making use of Wollstonecraft and Friedans theories, this article aims at examining to what extent the struggles of women are reflected and presented in the play. The struggles of the female characters are intrinsically concerned with the play and extrinsically relates to the condition of women in Ancient Rome. Upon analyzing, it becomes clear that Roman women had less rights and privileges than men and were considered inferior to men. Women in Roman were seen as weak, feeble and unworthy. Although feminism is not even heard of in Shakespeares time, through studying Wollstonecraft and Friedans theories, Portia and Calpurnias struggle can be considered as the springing of feminists actions.
INDONESIAN STUDENTS MISCONCEPTION IN USING PRESENT PERFECT TENSE TO WRITE COMPOSITION
Authors: Rochman Syaifur
Published: October 2021

This article describes a research on the error analysis in

the uses of present peifect tense made by freshmen studying at English

Department in "Universitas lenderal Soedirman (UNSOED). It

investigates the students' mistakes in using the present pelfect forms

when writing composition. The result shows that most rejpondents

still had difficulties in applying present perfect into sentences

appropriately. This is mainly due to the respondents' lack of

understanding on what the present peifect means. This suggests that

students should improve their understanding on the present perfect

given to its common use both in written and spoken English.