bluuebunny/crossref_metadata_2025 huggingface dataset:
A STUDY OF VESSEL MORPHOLOGIES FOR GRADING OF ASTROCYTIC TUMOURS IN INTRAOPERATIVE SQUASH SMEAR PREPARATIONS
Authors: Dhayal Sonu , Jindal Arpita
Published: March 2024

Introduction: Astrocytoma cause signicant morbidity due to impairment of brain functions in all ages and with equal sex predilection. A simple
procedure of intraoperative smear preparations leads us to diagnosis as well as grading of astrocytic tumors. Vascular features along with other
cytological characteristics of tumor helps us to differentiate between low grade and high-grade astrocytoma. To study the Aims and Objectives:
vessel morphologies in the cytological squash preparations of astrocytoma for intra operative diagnosis and grading and to study the morphological
characteristics of astrocytoma on cytology. This was an observational study of 50 cases of astrocyt Materials and Methods: oma. We studied the
vessel morphologies along with cytological features on squash smear preparation (stained by hematoxylin and eosin) for diagnosis and grading of
astrocytoma and correlated with histopathological diagnosis. There were 29 cases of low-grade astro Observations and Results: cytoma and 21
cases of high grade astrocytoma classied histologically according to WHO 2016 classication system. Mean vessel diameter and multiple
branching of vessel showed signicant difference between low grade and high grade astrocytoma (p value- 0.000). Vascular features Conclusion:
along with other cytological features are helpful in grading of astrocytic tumor on intraoperative squash smear preparations.
EFFECT OF MEDICAL QIGONG THERAPY ON FATIGUE , FUNCTIONALACTIVITY IN BUCCAL MUCOSA CANCER SUBJECTS UNDERGOING RADIATION THERAPY
Authors: Lahari Bindu , Kavitha N. , SureshKumar M. , Madhavi K.
Published: March 2024

Buccal mucosa carcinoma is the most common oral cavity cancer in India. One of the most frequent complications that cancer patients receiving
radiation therapy describe is fatigue. Medical Qigong therapy is a mind-body intervention aims for rejenuvation and healing. The aim of the study is
to know the effect of medical qigong therapy on fatigue and functional activity in buccal mucosa subjects undergoing radiation therapy. Need Of
The Study: This study investigates the impact of Medical Qigong therapy on buccal mucosa cancers, focusing on fatigue and functional activity
levels, aiming to ll gaps in existing research and inform comprehensive cancer care approaches. Aim Of The Study: It is to know the effect of
Medical Qigong therapy on fatigue, functional activity in Buccal mucosa cancer subjects undergoing radiation ttherapy. Objectives &
Methodology: This study evaluates the fatigue level and functional activity level. An experimental study was conducted in Radiation Oncology
department on 30 subjects with Buccal mucosa cancer undergoing radiation therapy aged 40-60 years. All the subjects performed Medical Qigong
walk cycle for 3 week days for 4 weeks from initiation of Radiation therapy. Scores of fatigue and functional activity using BFI and FIMS were
documented at baseline, and 4th week and compared the results between baseline and 4th week. Results: The 30 buccal mucosa cancer subjects of
mean age group 51.73 ± 5.349 years. The pre and post test scores on comparison of Fatigue and Functional activity levels found a clinically
statistical signicance with a P value (<0.001) of which showed a decrease in Fatigue levels and increase in Functional activity levels after
receiving 4 weeks of Medical Qigong therapy Conclusion: MQ therapy was effective in managing levels of fatigue and improving functional
activity of all buccal mucosa cancer subjects.
PANIC ATTACK WITH A RASH AFTER PERIPHERAL NERVE BLOCK.
Authors: Dabbeghatta Shashidhar
Published: March 2024

Panic attacks in patients in the operating theatre can pose a multitude of challenges to treating anaesthesiologists. As the symptoms are
comprehensive and varied, they can be confused with other emergency conditions like severe allergic reactions and local anaesthetic toxicity. We
report a unique case of a panic attack with a rash after axillary block for a thumb ligament reconstruction surgery in a patient with undiagnosed
anxiety illness. Twenty minutes after the block, the patient complained of breathing problems and dizziness which was associated with non-itchy
blotchy rash, tachycardia and hypertension. The rst episode was controlled by midazolam however she developed the same signs and symptoms at
the start of surgery following which general anaesthesia was administered and extubated uneventfully after the operation. We observe from this
report that rash could be associated with panic attacks and the presentation could easily confound us in arriving at the diagnosis in patients with
unreported or undiagnosed anxiety illness.
EFFECTIVENESS OF AEROBIC EXERCISES ON BODY MASS INDEX (BMI), PHYSICAL ACTIVITY AND MENSTRUAL DISTRESS LEVEL IN YOUNG FEMALE ADULTS WITH IRREGULAR MENSTRUATION
Authors: Thejaswani A. , Kumar M. Suresh , Kavitha N. , Madhavi K.
Published: March 2024

A regular menstrual cycle is indicative of a healthy reproductive system. Menstrual irregularities, commonly faced by young adults during their
periods, are often attributed to factors such as hormonal uctuations, insufcient physical activity, thyroid disorders, and dietary habits. The aim of
the study is “To know the effectiveness of aerobic exercises on body mass index (BMI), physical activity, and menstrual distress level in young
female adults with irregular menstruation”. This study aims to nd out the effect of aerobic exercise Need Of The Study: s on BMI, Physical
activity, and menstrual distress level in young adults with irregular and regular menstruation. It i Aim Of The Study: s to know the effectiveness of
aerobic exercises on body mass index (BMI), physical activity, and menstrual distress level in young female adults with irregular menstruation. An
experimental study. This study evaluates the BMI, physical activity level, and menstrual distress l Objectives & Methodology: evel. An
experimental study was conducted on 30 young female adults with irregular and regular menstrual groups of age groups between 19-25 years were
included in the study. All the subjects performed aerobic exercise for 6 weeks in non-consecutive days of irregular and regular menstrual groups.
The subjects who fullled the inclusion criteria were assigned to the irregular menstrual group(n=15), and regular menstrual group(n=15) based on
their menstrual history informed consent was obtained from all the subjects and the menstrual distress through the menstrual distress questionnaire
and the physical activity levels through the international physical activity questionnaire was measured at baseline and on completion of 6 weeks of
aerobic exercises. A total of 30 young individuals included in the study were assigned into an irreg Results: ular menstrual group (n=15), and a
regular menstrual group (n=15) of the mean age group 21.20 1.472 years. The pre and post scores comparison of BMI, Physical activity, and
Menstrual distress levels show clinical statistical signicance with P<0.05. The present study concl Conclusion: udes that aerobic exercise was
effective in regulating body mass index, increasing physical activity of young female adults, and decreasing menstrual distress levels in individuals
with irregular and regular menstrual groups.
DEVELOPMENT AND VALIDATION OF SCHOOL READINESS INVENTORY FOR PRESCHOOLERS WITH AUTISM SPECTRUM DISORDER
Authors: Missal Sujata , Kishor Dwivedi Amitabh
Published: March 2024

Background: Tools to assess school readiness skills targeting pre-schoolers with autism spectrum disorder (ASD) has been found to be sparse.
Objective: To develop and validate a school readiness inventory and manual for assessing school readiness in pre-schoolers with ASD. Methods:
Based on literature review, interview of experts and parents of children with ASD, study of previous school readiness scales, the inventory and
manual to assess school readiness was developed and reviewed by independent experts regarding the utility of the contents. Lawshe's content
validity ratio was used to assess the appropriateness of each item for inclusion in the inventory and manual. Results:Apanel of 8 experts conducted
content validation of the instrument and manual. The item content validity index (I-CVI) of instrument ranged from 0.75to 1.00. There was good
agreement in most of the 98 items except for 14 items (with < 0.78 I-CVI), which were modied based on the changes recommended by experts (n
=8). Conclusion: A school readiness inventory and manual to assess school readiness was developed and validated. Further studies are needed to
assess the utility of the scale in children with ASD.
A STUDY OF THE SOURCES AND MITIGATION STRATEGIES OF FINANCIAL RISKS IN LARGE-SCALE MAINTENANCE PROJECTS
Authors: Dhanaraj Duraisamy
Published: March 2024

Turnaround/Shutdown maintenance is one of the major maintenance activities for Oil & Gas and petrochemical plants. To implement the
maintenance activities such as asset integrity checks, long pending repairs, and major overhauls the plant should be shutdown. These activities shall
be carried out on a periodic basis to optimize a plant's performance, to meet statutory requirements such as government and Insurance norms.
Normally complete plant shutdown during turnaround maintenance is taking place for 50 days and organizations normally hire external contractors
to execute these massive activities in abbreviated period. Companies have economic loss during Turnaround time because of production loss,
business opportunity loss, higher maintenance cost and Health, safety, and environmental issues. Projects are nanced from company prots in the
year in which they are executed. This study shares industrial best practices to reduce nancial risk by reducing loss of prot which is occurring
because of turnaround maintenance projects. This explore deliberates principal project cost constraints and industry best practices to address those
risks.
HEMOPERITONEUM IN WOMEN OF REPRODUCTIVE AGE GROUP DUE TO CAUSES OTHER THAN ECTOPIC PREGNANCY.
Authors: Kumari Agitha
Published: March 2024

This case series illustrates hemoperitoneum in women of reproductive
age group due to causes other than ectopic pregnancy including
ovarian cyst rupture,endometriosis-related complications, traumainduced ovarian teratoma rupture and Corpus luteum cyst rupture.
Through these cases, we emphasize the importance of early
recognition, multidisciplinary medical care, and tailored surgical
procedures for improving patient outcomes . These ndings add to our
collective understanding of acute gynaecological emergencies and
underscore the need for future research to improve diagnostic and
treatment procedures in clinical practice.
FRACTIONAL DERIVATIVE MODEL ON RUMORS CAUSING STRESS WITHIN A FAMILY
Authors: Gupta Jyoti Kumari , Mishra Bimal Kumar
Published: March 2024

The act of spreading rumors within a society can have detrimental effects on individuals, including stress, hypertension, and anxiety. Given the
complexity of life as a dynamic system, it is crucial to address this chaos with utmost attention. The proposed fractional derivative epidemic model
for transmitting rumors in social networks highlights the importance of effective counseling and medical intervention in reducing the severity of
rumors. The fractional order parameter ρ is crucial in determining the stability of individuals recovering from the stress caused by rumor attacks.
This model incorporates Holling type II recovery rate to observe the effects of measures taken by the susceptible and infectious populations. Our
observations indicate that a decrease in the fractional order leads to an increase in stress and a decrease in recovery, while an increase in the
fractional order results in a decrease in stress and an increase in recovery. The simulation results indicate that the increase in the recovery rate can be
attributed to the successful implementation of counseling and medical interventions. It is recommended to prioritize addressing lower values of ρ
and take measures to identify and address individuals who spread rumors to reduce stress and anxiety within society.
A COMPARATIVE STUDY OF 0.5% BUPIVACAINE HEAVY VERSUS 0.5% BUPIVACAINE HEAVY PLUS DEXMEDETOMIDINE IN SPINAL ANESTHESIA FOR INFRAUMBILICAL SURGERIES: A PROSPECTIVE, RANDOMIZED STUDY
Authors: Shankar B Gowri , N Keerthana , Bhukya Raju
Published: March 2024

Background: Ensuring appropriate intraoperative anesthesia and postoperative pain management for infraumbilical surgery remains a signicant
challenge. However, the use of adjuvants such as dexmedetomidine in spinal anesthesia has been shown to extend the duration of pain relief in the
postoperative period. Recent studies have demonstrated substantial improvements in postoperative pain management and stable intraoperative
conditions when dexmedetomidine is used as an adjuvant in spinal anesthesia. To assess the efcacy of adding dexmedetomidine to bupivacaine
heavy in spinal block compared to using plain bupivacaine heavy in patients undergoing infraumbilical surgeries, a prospective, randomized study
was conducted. Sixty patients scheduled for infraumbilical surgeries were randomly assigned to two Methods: groups: one group received
dexmedetomidine along with 0.5% bupivacaine heavy, and the other group received plain 0.5% bupivacaine heavy in equal volume. The Results:
beginning of sensory blockade in Group C occurred at (151.66 ± 15.33 seconds) and in Group D at (128.66 ± 11.36 seconds), with a statistically
signicant difference (p < 0.001). In Group C, the peak sensory block was reached at (9.41 ± 0.56) and in Group D at (7.33 ± 0.73). The highest
dermatomal sensory level observed in Group C was (6.8 ± 1.09 minutes) and in Group D was (5.96 ± 0.67). The onset of motor block in Group C
was at (178 ± 16.48 seconds) and in Group D and (140 ± 13.89 minutes). Complete motor block was achieved in Group C at (8.6 ± 0.57 minutes) and
in Group D at (6.67 ± 0.63 minutes) (p < 0.001). The regression of sensory block to two segments in Group C was (92.83 ± 8.37 minutes) and in
Group D (146.83 ± 9.14 minutes) with p < 0.001). The regression to T12 in Group C was (139.5 ± 13.60) and in Group D at (208.116 ± 16.21).
Complete recovery of motor block was observed in Group C (179.16 ± 14.62) and Group D (265.66 ± 19.24). The total duration of analgesia in
Group C was (187.5 ± 15.07 minutes) and in Group D was (301 ± 25.77 minutes). Group D exhibited a r Conclusion: apid onset of sensory and
motor block, and the duration of the motor and sensory block was signicantly longer than in Group C. The total analgesia duration in Group D was
also longer. Moreover, adding dexmedetomidine to spinal anesthesia provided better surgical conditions and analgesia compared to plain
bupivacaine.
RISK FACTORS AND PROGNOSTIC DETERMINANTS OF DUODENAL ULCER PERFORATION.
Authors: Abhang Satshil Chandrakant , Abhang Prajakta Satshil , Muntode Nilesh Namdeo
Published: March 2024

Background: Duodenal ulcer perforation (DUP) is one of the most common acute-abdominal emergencies in the eld of general surgery. It is
associated with mortality rates. Studies have reported variety of factors that determine the prognosis of DUP. These include advanced age, major
and chronic medical conditions, peri-operative hypotension, and delay in diagnosis and management. The present study was conducted in a tertiary
care teaching hospital with an aim to determine risk factors and prognostic determinants of DUP. Methods: Patients of > 18 years of age presenting
with perforated chronic duodenal ulcers were included. The diagnosis of DUPwas made by the treating surgeon and was based on clinical features.
Radiological investigation supplemented clinical diagnosis whereas ndings during surgery were used as conrmed diagnosis. Results:Advanced
age, male gender, consumption of non-steroidal anti-inammatory drugs (NSIDs), smoking tobacco and drinking alcohol were important risk
factors for DUP. Surgical site infections were the commonest post-operative complications. The mortality rate was 9.8%. Conclusion: DUP is
associated with high morbidity and mortality rates regardless of its cause. Smoking, alcohol consumption and use of NSAIDs are important risk
factors for DUP. Surgical site infections are common post-operative complications. High morbidity and mortality rates underscore the importance
of prompt diagnosis and appropriate surgical and medical interventions for better outcome.
A NEW AESTHETIC CONCEPT FOR TEETH RESTAURATION – CASE REPORT
Authors: Jovanovski Andrej , Mijoska Aneta , Jovanovski Sasho
Published: March 2024

Background: Methodology: To investigate impact of novel inner ferrule preparation around cervical part of root canal. A case report featuring
endodontically treated tooth restored with newly designed zirconia ceramic post. Special drills were used for horizontal root canal preparation
around cervical part and post spaces in canal, leaving at least 3 mm gutta-percha apical seal. Zirconia ceramic posts were cemented with Multilink
Automix, upgraded with Multi-Core and zirconia crowns. IF preparation design and new post-core desi Results: gn with retentive rings in the
coronal part showed stronger retentive coronal design. IF preparation and retentive rings of the zir Conclusion: conia post contribute to increased
fracture strength. Rehabilitation signicantly reduced the severity of root fracture for excellent function and aesthetics.
Un altro concetto di sostenibilità
Authors: Lucarelli Paola
Published: March 2024

The chapter is introductory in nature and sets out the rationale for the multidisciplinary study, finding sustainability as the guiding principle of justice system reform interventions as well. Indeed, this has confirmed its relevance in the country's recovery process following the pandemic, attracted the attention of legislators engaged in reforms, as well as universities in designing innovative models for justice efficiency and effectiveness. The pursuit of the goals assumed in the National Recovery and Resilience Plan assigns a central role to strengthening the trial office by recruiting a large number of staff. How the activities of the office are carried out, in particular with what contribution and purposes the different professional skills interact, can become strategic for a justice that is both sustainable and efficient.
Peritoneal Tuberculosis Simulating an Ovarian Tumor at the Peritoneal Carcinomatosis Stage: A Case Report
Authors: Laleye Christel Marie , Kamga Felix Telesphore , Attolou Setondji Gilles Roger , Gnangnon Fréddy , Tchouya Karelle , Sourokou Fadel , Gbessi Dansou Gaspard , Mehinto Delphin Kuassi
Published: March 2024

The peritoneal location of tuberculosis can simulate advanced ovarian cancer. It’s a diagnostic problem due to the non-accessibility of specific examinations. We report a case of 41-year-old female with pseudo-tumoral peritoneal tuberculosis, suspecting ovarian cancer, associated with peritoneal carcinomatosis. The diagnosis was made on exploratory laparotomy and biopsy of the peritoneal granulations, the patient was put under a classic anti-tuberculosis therapeutic regimen (2ERHZ/4RH), with good outcomes. It’s essential before any invasive ovarian surgery to provide histological proof of the cancerous nature of the lesions. This attitude would not be substituted by experience.
A Rule-Based Expert System for Academic Advising and Guidance Toward Undergraduate Students
Authors: Albulushi Mr. Abdul Rahman
Published: March 2024

The provision of academic guidance to undergraduate students is a crucial and significant duty for the academic faculty in most prestigious universities. Expert systems are often regarded as one of the most successful areas in the field of artificial intelligence. The system utilizes a rule-based decision engine to assist individuals lacking experience in enhancing their skills. Nevertheless, a significant number of students are required to meet with their advisors to arrange their study schedule. This thesis is driven by the belief that the successful development of an academic advisory expert system will result in an expansion of the range and extent of challenges that students, academic staff, and other academic activities can effectively address, leading to a higher level of achievement in the university learning process. Nevertheless, the effectiveness of an advisory expert system is constrained by the caliber of the acquired knowledge, specifically in the context of academic advisory expert systems. The performance of such systems is primarily determined by the quality of the framework employed for academic expert knowledge acquisition. The objective of this study is to suggest a revision of the current knowledge acquisition framework in order to make it appropriate for implementation in higher education institutions. The proposed modification aims to create a prototype rule-based expert system specifically designed for academic advising of undergraduate students. The system's output also offers a precise and conflict-free course proposal for the undergraduate student. It functions as a mentor, providing undergraduate students with guidance and recommendations for suitable subjects based on their completed courses, prerequisites, and project scope, as defined by the student themselves. According to the empirical findings, the utilization of the proposed model for an undergraduate advisory expert system resulted in a noteworthy enhancement in performance.
Isolated Skin Pantoea Agglomerans Infection: An Entomodermoscopy Description
Authors: Fliti Amani , Alaoui Meryem Elomari , Meziane Mariame , Ismaili Nadia , Benzekri Laila , Senouci Karima
Published: March 2024

Pantoea agglomerans is an environmental and agricultural gram-negative aerobic bacilli, and it uncommonly causes skin infections and presents with nonspecific clinical and histological findings. Hereby, we report a unique rare case of isolated cutaneous infection with Pantoea gglomerans with a first entomodermoscopy description.
Anti- Synthetase Syndrome with Kaposi Sarcoma: An Unusual Association
Authors: Fliti Amani , Alaoui Meryem Elomari , Meziane Mariame , Ismaili Nadia , Benzekri Laila , Senouci Karima
Published: March 2024

Kaposi sarcoma (KS) is a rare angioproliferative tumor whose etiology is associated with human herpesvirus 8 and it is widely known as a complication of acquired immunodeficiency syndrome and, the assocciation with anti synthetase syndrome (ASS) have rarely been reported. Herein we present a case of a 64-year-old woman diagnosed with ASS and Kaposi’s disease as a rare association.
Ocular Manifestations Revealing of Behçet's Disease: About 42 Cases
Authors: Elkhoyaali Adil , Chaibi Zakaria , Laaouina Soukaina , Zamani Falak , Mouzarii Yassin , Oubaaz Abdelbar
Published: March 2024

Introduction: Behçet's disease is a chronic, autoimmune, multisystem of unknown etiology, characterized by oral ulcers, genital ulcers, and eye lesions. Ophthalmological manifestations of Behcet's disease are numerous and are often indicative of the disease. Our job is to study these events in a group of patients in whom the ophthalmologic involvement was indicative of Behcet's disease. Materials and Methods: A retrospective study in the ophthalmology department at the military hospital of instruction Mohamed V in Rabat between January 2009 and December 2015. It involved 42 patients who initially consulted for eye symptoms and in that the diagnosis of Behçet's disease was selected based on the criteria of ISG. Results: The initial ocular demonstrations were non-granulomatous anterior uveitis in (15,06%) of which (10,9%) with hypopyon, intermediate uveitis (9.5%), ocular hyalite (12.32%), panuveitis in (41,1%), retinal vasculitis (16.43%), retinal vein occlusion (3.6%), papillary edema (1.8%). The criteria used for the diagnosis of Behcet's disease were essentially have oral ulceration, genital ulceration and pathergy test. Discussion: In 10% to 20% of cases, ocular involvement may be opening, remaining isolated for several years. The most frequently revealing clinical aspects of Behcet's disease are the anterior uveitis, and vasculitis panuveites. Conclusion: the ethnic and geographic origin of the patient, the young age and some clinical features of ocular lesions should remind ophthalmologists to Behcet's disease to inflammation of one of the ocular structures and encourages him to seek other diagnostic criteria in collaboration with other specialities
LÚPUS ERITEMATOSO SISTÊMICO, CONSIDERAÇÕES E TRATAMENTOS: UMA REVISÃO INTEGRATIVA
Authors: Giovannini Sad Ribeiro João Vítor , Jatobá Barbosa João Vitor , De Castro Honorato Jordana , Brunetti Teles de Melo Júlia , Drummond de Moura Miguez Laura
Published: March 2024

Introdução: O Lúpus Eritematoso Sistêmico (LES), é uma doença inflamatória crônica autoimune e multissistêmica, com variadas apresentações clínicas, sendo que acometimentos articulares e cutâneos são os mais comuns, e possui maior frequência em mulheres jovens e de meia idade. Objetivo: O presente artigo tem como objetivo resumir e apresentar dados e considerações atuais sobre o LES, com enfoque maior em seus variados tratamentos. Método: Foram realizadas pesquisas nas bases de dados Medline, Scielo e LILACS. Critérios inclusivos: artigos escritos em inglês, espanhol ou português e publicados a partir do ano de 2016. Critérios excludentes: artigos que não se relacionavam ao tema proposto e/ou publicados anteriormente à 2016. Ademais, não foram utilizados artigos de revisão para a produção dos resultados. Resultados: Os artigos analisados evidenciaram o LES como uma doença oriunda de fatores ambientais e genéticos, com a correspondência de loci para a condição, entretanto a etiologia ainda não é clara. Quanto aos tratamentos, a necessidade de se controlar a resposta imune é evidente e os meios para isso dependem, além da eficácia da medicação, da resposta do paciente e quais efeitos adversos ele suporta. Dentre os tratamentos analisados, seus resultados mostram-se promissores e se faz necessário avaliar individualmente a aplicação de cada um. Conclusão: Vale ressaltar a importância de variados tratamentos, escolhendo o melhor para cada tipo de paciente. Contudo, mais estudos são necessários para compreender a condição do LES por inteiro, e tornar cada vez melhor a abordagem do paciente e o tratamento.
AVALIAÇÃO DE RISCOS E BENEFÍCIOS DO USO DE CONTRACEPTIVOS HORMONAIS EM MULHERES COM FATORES DE RISCO PARA DOENÇAS CARDIOVASCULARES
Authors: Dias Renan Italo Rodrigues , Maia Yana Mirian Martins , Braz João Pedro Mendonça Raphael , Medeiros Heitor Goes de Araújo , Silva Umbelina Fernanda Estrela da , Costa Matheus Fonseca da , Santos Bruna Moura , Lima Aloysio de Sousa Cunha , Souza, Barbara Priscila Alves de , Brito Carla Andrea Moretto , Oliveira Raquel Pereira de , Brito Jessica Amanda Almeida
Published: March 2024

A avaliação de riscos e benefícios do uso de contraceptivos hormonais em mulheres com fatores de risco para doenças cardiovasculares é crucial para a saúde da mulher. Embora os contraceptivos hormonais sejam eficazes na prevenção da gravidez, eles também apresentam riscos potenciais, especialmente em mulheres com histórico familiar ou outros fatores de risco para doenças cardiovasculares, como tabagismo, hipertensão arterial e obesidade. Os principais benefícios incluem regulação do ciclo menstrual, redução do risco de câncer de ovário e endométrio, e melhora dos sintomas da síndrome dos ovários policísticos. No entanto, é fundamental realizar uma avaliação individualizada do perfil de risco cardiovascular de cada paciente antes de iniciar o uso de contraceptivos hormonais. Além disso, é importante considerar opções alternativas de contracepção em mulheres com alto risco cardiovascular, como dispositivos intrauterinos não hormonais. Uma abordagem multidisciplinar, envolvendo médicos ginecologistas, cardiologistas e outros profissionais de saúde, é essencial para garantir a segurança e a eficácia do uso de contraceptivos hormonais em mulheres com fatores de risco para doenças cardiovasculares. Esta revisão visa aprofundar a compreensão desses riscos e benefícios, bem como destacar as medidas para uma abordagem individualizada e segura na prescrição de contraceptivos hormonais. Mulheres com fatores de risco para doenças cardiovasculares, como tabagismo, hipertensão arterial, diabetes mellitus, obesidade, dislipidemia e história familiar de eventos cardiovasculares precoces, podem apresentar um perfil de risco aumentado ao utilizar contraceptivos hormonais. Estrogênio e progestina, os principais componentes desses contraceptivos, podem influenciar o sistema cardiovascular de várias maneiras, incluindo alterações no perfil lipídico, aumento da coagula ilidade sanguínea e efeitos sobre a função endotelial e vascular. Embora os contraceptivos hormonais ofereçam uma série de benefícios além da contracepção, como regulação do ciclo menstrual, redução do risco de câncer de ovário e endométrio, e melhora dos sintomas da síndrome dos ovários policísticos, é essencial ponderar cuidadosamente esses benefícios em relação aos riscos cardiovasculares potenciais em cada paciente.
OPTIMIZACIÓN DEL MANEJO TERAPÉUTICO EN LA HEMORRAGIA DIGESTIVA ALTA: TRAS LAS HUELLAS DE LA SANGRE PERDIDA.
Authors: Cedeño Hugo Andrés Fernández , Valdez Luisa Lisbeth Meza , Reyes Fernanda Valentina Vélez , López Jairo José Ponce , Anchundia Shirley Tatiana Calderón , Yaguana Sally Mabel Zambrano , Bodero Wendy Mireya Rojas , Ortega Denisse Izquierdo , Vera Carlos Andrés Muentes , Loayza Karina Mercedes Montero
Published: March 2024

La investigación se enfoca en la optimización del manejo terapéutico en la hemorragia digestiva alta, una condición médica grave con diversas causas y síntomas. Objetivo: analizar la literatura científica más reciente de una forma critica para sintetizar el conocimiento actual sobre la hemorragia digestiva alta. Metodología: Se realizó una exhaustiva revisión bibliográfica en bases de datos reconocidas, limitando la búsqueda a estudios en inglés y español de los últimos cinco años y enfocándose en estudios originales, revisiones sistemáticas.  Resultados y discusión: Los factores de riesgo de la HDA incluyen la edad avanzada, enfermedades coexistentes, uso de anticoagulantes y antiinflamatorios no esteroides, e infección por Helicobacter pylori. Los síntomas varían desde hematemesis y melena hasta debilidad y desmayos. El manejo adecuado de la HDA es crucial para mejorar los desenlaces de los pacientes y depende de la causa subyacente. El tratamiento puede incluir endoscopía temprana, técnicas térmicas, inyección de agentes esclerosantes o adrenalina diluida y cirugía en casos refractarios. En HDA varicosa, los pacientes presentan un índice de gravedad más elevado y requieren cuidados especiales, incluyendo la evaluación del nivel de Child Pugh, escleroterapia o ligadura, instalación de una sonda de Sengstaken-Blakemore y uso de somatostatina o sus análogos. En situaciones específicas, el Shunt Portosistémico Intrahepático Transyugular puede ser una opción de tratamiento efectiva.
Explorando a Relação Entre Experiências Adversas na Infância e Transtornos Psiquiátricos na Vida Adulta: Uma Revisão Longitudinal
Authors: Rodrigues Danjo Samira , Torres Rosa Maria Clara , Milanez Scantamburlo Isabela , Figueiredo Moises Marília , Bruske Caroline , Brizolla Nicole Fernandes Jorge , Rodrigues Danjo Nicolas , Mamede Suleiman Yasmin , Rodas Glanzmann Giovanni , Vieira Macêdo Natalia Caroline
Published: March 2024

Explorando a relação entre experiências adversas na infância e transtornos psiquiátricos na vida adulta, diversas abordagens terapêuticas são examinadas para lidar com os efeitos dessas experiências. Há uma ênfase tanto nas intervenções farmacológicas quanto nas não farmacológicas. Inicialmente, ressalta-se a eficácia das intervenções farmacológicas recentes, que buscam controlar os sintomas dos transtornos psiquiátricos e melhorar a qualidade de vida dos pacientes. Essas terapias não se restringem apenas ao alívio dos sintomas, mas também têm como objetivo abordar as causas subjacentes desses transtornos, considerando a complexa interação entre fatores neurobiológicos e ambientais.

Além das intervenções farmacológicas, estão sendo exploradas abordagens não farmacológicas inovadoras, como terapias comportamentais e modulação do estilo de vida. Essas estratégias incluem terapias cognitivo-comportamentais, treinamento de habilidades sociais e técnicas de relaxamento, que demonstraram ser eficazes na redução dos sintomas dos transtornos psiquiátricos e no gerenciamento do estresse. A pesquisa contínua nesse campo é crucial para identificar as abordagens mais eficazes e adaptá-las às necessidades individuais dos pacientes.

Ademais, é relevante destacar o papel de medicamentos específicos no tratamento dos transtornos psiquiátricos associados às experiências adversas na infância, incluindo antidepressivos, ansiolíticos e estabilizadores de humor. Esses medicamentos visam controlar os sintomas dos transtornos psiquiátricos, proporcionando alívio aos pacientes afetados pelas experiências adversas na infância. Em síntese, a abordagem no tratamento dos transtornos psiquiátricos relacionados às experiências adversas na infância está cada vez mais focada na combinação da terapia farmacológica e não farmacológica.

A integração dessas estratégias terapêuticas pode oferecer uma abordagem mais abrangente e personalizada para o manejo desses transtornos, melhorando significativamente a qualidade de vida dos pacientes. No entanto, são necessárias mais pesquisas para compreender completamente os mecanismos subjacentes e otimizar o uso dessas intervenções terapêuticas na prática clínica.
The Relationship between Nutritional Knowledge with Nutrient Intake and Adherence to the Consumption of Blood-Added Tablets in Adolescent Girls at SMA Islam SHAFTA Surabaya
Authors: Rahmawati Septalia Puji , Intiyati Ani , Hatijah Nur , Soesanti Inne
Published: March 2024

ABSTRACT
Anemia is a nutritional problem of adolescents in Indonesia that occurs due to iron deficiency. The purpose of the study was to analyze the relationship of nutritional knowledge with nutrient intake and adherence to the consumption of blood-added tablets in adolescent girls at SMA Islam SHAFTA Surabaya. This type of research is analytical descriptive research with a cross sectional design. Large sample of 45 respondents. Data collection with interviews and SQ-FFQ. Furthermore, it was analyzed with the spearman correlation test. The results of the analysis indicate that the majority of respondents' characteristics are aged 16-18 years (68.9%). Good nutrition knowledge 35 respondents (77.8%). Protein intake 32 respondents (71.1%) severe deficit, iron intake 36 respondents (80%) deficient and 41 respondents (91.1%) non-compliant. There was no relationship between nutritional knowledge with protein intake (p value = 0.428), nutritional knowledge with iron intake (p value = 0.685), and nutritional knowledge with adherence to blood added tablet consumption (p value = 0.231). There is no relationship between variables and it is necessary to collaborate on independent blood added tablets and health counseling at school.
Acceptance Test and Iron Content Test Churros Formulation of RALE Flour (Red Beans and Soybeans) as an Alternative Snack to Prevent Anemia for Teenage Girls
Authors: Rhodiyah Ayunis Naba'ur , Juliana Christyaningsih  , Wijayanti Erlyna Jayeng , Intiyati Ani
Published: March 2024

Conditions in which the amount of hemoglobin in the blood is below normal limits is called anemia. Iron deficiency is one of the causes of anemia which is still common in pregnant women and adolescents. The aim of this study was to determine the acceptability and levels of iron in churros formulated by RALE (red bean and soybean flour) as a snack to prevent anemia for girls. The research method is an experiment on 3 formulations of adding many flours: red bean: soybean with the formulations CP 1 (85:5:10), CP 2 (75:10:15), and CK 3 (100:0:0), using organoleptic tests in the form of likes and dislikes for color, taste, aroma, texture which were presented to 25 panelists. Test for iron content using ICP-OES method for the best organoleptic formulation and test results (CK 3). The results showed the CP 1 formulation were the most preferred with an average score of 4.32 which was included in the like category. The conclusion of this study showed organoleptic properties, the formulation favored by the panelists was the CP 1 formulation with a ratio of flour: red bean flour: soybean flour of 85:5:10, having an iron content of 3.86 mg/100 grams churros.
Test of Acceptance and Iron Content of Baymor “Red Spinach & Moringa” as a Treat to Prevent Anemia in Adolescent Women
Authors: Rosyidah Anisah Rona , Christiyaningsih Juliana , Pengge Nuning Marina , Hatijah Nur
Published: March 2024

Based on DP3AK 2021 East Java, 23% of young women and 12% of young men suffer from anemia. Red spinach and Moringa leaves are contain high levels of iron so it can be used as alternative foods to prevent anemia in young women. The purpose was to analyze the results of tests of acceptability and iron levels of "red spinach & moringa" baymor cake as a snack to prevent anemia in young women. The research method is experimental research. Data will be analyzed using the Kruskal Wallis test, if the results are p <0.05 then it will be continued using the Mann Whitney test. The average result of the acceptability test is the BM 1 formulation which is 4.04 (likes it), BM 2 which is 3.49 (rather likes it) and BM 3 which is 3.2 (rather likes it). The results of iron levels in the control formulation (BM 1) were 3.63 mg/100g and the most preferred formulation was BM 2 of 9.81 mg/100g. The control formulation (BM 1) with iron content of 3.63 mg/100g was the most preferred formulation by the panelists, while the second most preferred formulation was BM 2 of 9.81 mg/100g.
I. Kant y Lon L. Fuller: sobre el estado jurídico
Authors: Cubo Ugarte Oscar
Published: March 2024

Kant y Lon L. Fuller rara vez se consideran pensadores afines. Sin embargo, para mostrar su afinidad intelectual voy a exponer, en primer lugar, los requisitos específicos de la moralidad interna del derecho presentados por Lon L. Fuller en The Morality of Law (1964) a propósito del monarca Rex. A continuación, y, en segundo lugar, voy a comparar tres de los requisitos fundamentales de la moralidad interna del derecho (la generalidad de la ley, la promulgación y la no-retroactividad de la ley) con las reflexiones que desarrolla I. Kant en su “Doctrina del derecho” de la Metafísica de las Costumbres (1797) acerca de la justicia pública y el derecho penal. Finalmente refuerzo el resultado de los dos apartados anteriores y muestro la afinidad intelectual de ambos autores en relación con un peculiar requisito específico de la moralidad interna del derecho, a saber, que las leyes deben prescribir lo posible a sus destinatarios. Propongo una interpretación del mencionado requisito a partir del concepto del derecho de la humanidad de I. Kant.
Simulation model of selective assembly of three elements with sorting
by estimated values
Authors: Filipovich Oleg V.
Published: March 2024

The process of one-parameter selective assembly of three elements is considered. Methods for decreasing
the probability of sorting errors are presented. It is proposed to carry out the sorting process according to the values of
the parameter estimates obtained using the recurrent algorithm. A simulation model of selective set-making and assembly
of three elements has been built to determine the indicators of the assembly process. Comparative simulation results are
presented, proving the effectiveness of the application of the parameter estimation algorithm.
Qualification check and assessment of the quality of work
of employees in the assembly production
Authors: Rodionova Elena N. , Anisimova Marina A. , Kichanova Anna A. , Nuzhdin Georgy A.
Published: March 2024

The applicability and adequacy of the use of model of internal quality of results work in the fi eld of verifi cation
measuring instruments and the developed method internal laboratory quality control of the results of work in the fi eld of
verifi cation of measuring instruments are shown. It has been confi rmed that internal quality control is based on information
obtained in the process assessment procedures errors using control measurements.
Optimization of the manufacturing process of the sensitive coil
of the fiber-optic gyroscope
Authors: Esaulov Vasilij V. , Rozhko Tat'yana E. , Koloskov Aleksandr V.
Published: March 2024

The article considers an alternative version of the technological process of manufacturing a sensitive coil
of a fi ber-optic gyroscope, namely, impregnation of the fi ber contour of the coil, pre-wound "dry".
The advantages and diffi culties of the proposed method are analyzed. The test results of the fi ber-optic gyroscope are
presented, and further directions of work are proposed.
Assessment of the influence of mechanical and heat treatment
on the level of residual stresses in the part "brake drum"
Authors: Boldyrev Denis A. , Popova Larisa I. , Prasolov Sergey G.
Published: March 2024

The problem of instability of the geometry of the part "brake drum" when it is obtained from the casting by
high-speed non-burnished turning, affecting the occurrence of the operational defect "noise/knock of the rear suspension",
associated with the level of residual casting stresses, is indicated. A method for estimating the level of residual elastic
deformations in parts and cast blanks based on the Davidenkov method is proposed. Using this technique, the elasticstress
state in fi nished parts and castings in the delivery state and after annealing was analyzed. It is established that the
infl uence of mechanical processing on the level of residual stresses for cast and annealed castings is generally nonlinear:
mechanical processing increases the level of residual stresses in cast castings by 3,5 times compared to annealed.
Islamic Spiritual Care with Murottal for Reducing Anxiety and Depression in Coronary Heart Disease Patients: A Comprehensive Systematic Review
Authors: Wisuda Aris Citra , Sansuwito Tukimin bin , Suraya Citra
Published: March 2024

Background:Spiritual care is a vital aspect of the nursing process, particularly for palliative patients such as those with Coronary heart disease. While pharmacological and medical interventions remain paramount for managing heart conditions, the efficacy of Islamic spiritual therapy with Murottal has also been significant. Research has demonstrated its notable influence on patients' quality of life, particularly in mitigating anxiety and depression.
Objective:This study aims to conduct a systematic review to explore the role of Islamic spirituality in nursing, specifically through Murottal recitations, and its impact on anxiety and depression among Coronary heart disease patients.
Method:Employing a systematic review design, we utilized various electronic databases including PubMed, ProQuest, Science Direct, DOAJ, Wiley, Garuda, and secondary PubMed-indexed sources from 2018 to 2023. Inclusion criteria comprised studies with a clear definition of spiritual care involving Murottal in nursing, confirmed Coronary heart disease diagnoses, and reporting outcomes such as the incidence of death, cardiovascular outcomes, and quality of life.
Result:The search focused on examining the correlation between Islamic spiritual care with Murottal and the quality of life in patients with coronary heart disease. Following a rigorous methodology, which included study selection, critical appraisal, data extraction, and synthesis, the search yielded 1,286 articles, with seven meeting the inclusion criteria. Analysis and categorization of these articles based on evidence level and recommendations revealed a consistent association between Islamic spiritual care with Murottal and reduced anxiety and depression in Coronary heart disease patients. However, heterogeneity was observed in research instruments, implementation duration, and outcomes.
Conclusion:The conclusive evidence from this review supports the notion that Islamic spiritual care, particularly through Murottal recitations, significantly impacts the quality of life among Coronary heart disease patients.
Keywords: Anxiety, Coronary Heart Disease, Depression, Murottal, Spiritual Care
FORECASTING THE FUTURE: A COMPARATIVE ANALYSIS OF ML AND DL MODELS IN SUPPLY CHAIN DEMAND PREDICTION
Authors: Rishi Varsha Poranki  , Kalyani Pattima  , Meghana Yalagala  , Namitha Suraboina  , K. Thrilochana Devi
Published: March 2024

Supply chain demand forecasting is a strategic process aimed at predicting future customer demand for products within the broader framework of a supply chain. This involves forecasting the anticipated quantity of goods or services that customers will purchase and seamlessly integrating this insight into the overall supply chain management. The primary goal is to synchronize production, procurement, and distribution activities with expected demand, thereby optimizing inventory costs, minimizing instances of under stocking or overstocking, reducing waste, and ultimately enhancing overall supply chain efficiency. The emphasis is on leveraging advanced technologies, including deep learning techniques such as CNN, LSTM, CNN+LSTM, GRU, and machine learning techniques like Linear Regression and XGBoost, to achieve accurate predictions. By implementing these algorithms, businesses can construct a robust forecasting system capable of monitoring changes in demand and aligning supply accordingly. This proactive approach empowers retailers to enhance their inventory and planning efficiency, ultimately contributing to increased customer satisfaction.
KEY WORDS: Machine Learning, Deep Learning, XG Boost, Linear Regression, CNN, LSTM, CNN+LSTM, GRU
Matrix metalloproteinase-1 as a potential biomarker for early gastric cancer detection and its effect on gastric cancer cell proliferation and migration
Authors: Yi Ke , Hu Yan , Zhu Xiaoli , Li Qing
Published: March 2024

The present study aimed to investigate the association between matrix metalloproteinase-1 (MMP-1) and early gastric cancer (EGC), while also evaluating the effect of MMP-1 on gastric cancer cell proliferation and migration. Transcriptome RNA sequencing and database analysis were conducted to assess the relationship between MMP-1 expression and EGC. Differences in MMP-1 expression between clinical EGC samples and paracancerous tissues were detected using fluorescence quantitative polymerase chain reaction (PCR). In N87 gastric cancer cells, changes in proliferation- and migration-related indicator expression were determined. Gene sequencing revealed differential expression of MMP-1 in early and advanced gastric cancers. Furthermore, enhanced MMP-1 expression was observed in early and advanced gastric cancer tissues, exhibiting a positive correlation with the malignant phenotype in gastric cancer cell lines. Fluorescence quantitative PCR revealed considerably higher MMP-1 expression in EGC tissues than in paracancerous tissues. CCK8 and EdU assays demonstrated a significant increase in N87 cell proliferation on MMP-1 upregulation and a decrease on its downregulation. The scratch assay results demonstrated a corresponding enhancement in N87 cell migratory capacity with MMP-1 upregulation, which was attenuated on its downregulation. Western blot experiments revealed a decrease in the expression of the epithelial-mesenchymal transition-related protein E-cadherin after MMP-1 upregulation, while vimentin expression significantly increased. Conversely, the downregulation of MMP-1 led to opposite outcomes. Overall, MMP-1 emerges as a potential biomarker for EGC diagnosis and plays a crucial role in the regulation of N87 gastric cancer cell proliferation and migration.