bluuebunny/crossref_metadata_2025 huggingface dataset:
Total Serum Magnesium Levels and Calcium-To-Magnesium Ratio in Sickle Cell Disease
Authors: Antwi-Boasiako Charles , Kusi-Mensah Yaw A. , Hayfron-Benjamin Charles , Aryee Robert , Dankwah Gifty Boatemaah , Kwawukume Lim Abla , Darkwa Ebenezer Owusu
Published: August 2019

Background and Objectives: Imbalance of calcium/magnesium ratio could lead to clinical complications in sickle cell disease (SCD). Low levels of magnesium have been associated with sickling, increased polymerization and vaso-occlusion (VOC) in sickle cell due to cell dehydration. The K-Cl cotransport plays a very important role in sickle cell dehydration and is inhibited by significantly increasing levels of magnesium. The study evaluated total serum magnesium levels and computed calcium/magnesium ratio in SCD patients and “healthy” controls. Materials and Methods: The study was a case-control cross-sectional one, involving 120 SCD patients (79 Haemoglobin SS (HbSS)and 41 Haemoglobin SC (HbSC)) at the steady state and 48 “healthy” controls. Sera were prepared from whole blood samples (n = 168) and total magnesium and calcium measured using a Flame Atomic Absorption Spectrometer (Variant 240FS manufactured by VARIAN Australia Pty Ltd., Melbourne, VIC, Australia). Calcium/magnesium ratios were calculated in patients and the controls. Results: The prevalence of hypomagnesemia and hypocalcaemia among the SCD patients was observed to be 39.17% and 52.50% respectively, higher than the controls (4.17% and 22.92%, for hypomagnesemia and hypocalcaemia, respectively). Level of magnesium was significantly lower in the SCD patients compared to their healthy counterparts (p = 0.002). The magnesium level was further reduced in the HbSS patients but not significantly different from the HbSC patients (p = 0.584). calcium/magnesium ratio was significantly higher in the SCD patients (p = 0.031). Although calcium/magnesium ratio was higher in the HbSC patients compared to those with the HbSS genotype, the difference was not significant (p = 0.101). Conclusion: The study shows that magnesium homeostasis are altered in SCD patients, and their levels are lower in HbSS patients. Although calcium/magnesium ratio is significantly higher in SCD patients compared with controls, there is no significant difference between patients with HbSS and HbSC genotypes. Magnesium supplementation may be required in sickle cell patients.
Emergence of Rickettsial Infection in Rainbow Trout (Oncorhynchus mykiss) Fry Displaying the Appearance of Red Mark Syndrome in Korea
Authors: Oh Woo Taek , Giri Sib Sankar , Yun Saekil , Kim Hyoun Joong , Kim Sang Guen , Kim Sang Wha , Kang Jeong Woo , Han Se Jin , Kwon Jun , Jun Jin Woo , Park Se Chang
Published: August 2019

Red mark syndrome (RMS) is a fish disease caused by the infection of Rickettsial agents, especially affecting rainbow trout (Oncorhynchus mykiss). The disease is prevalent in many countries in Europe (France, Switzerland, Italy, and Slovenia), South America (Chile), North America (USA), and even Asia (Japan). However, it has not been reported in Korean aquaculture. In February 2019, rainbow trout presenting red spot lesions with swollen features on the lateral side of their body were observed at a hatchery in Korea. Fishes showing those clinical signs were fry weighing 25 ± 5 g. Moreover, the fish showing the red spot lesions were found dead, which suggests an outbreak of a mortality-causing disease. The symptoms were similar to those of RMS, and we identified the presence of Rickettsia-like organisms associated with this disease using polymerase chain reaction (PCR), sequencing, histopathologic examination, and transmission electron microscopy. The distinct features of this infection, compared to that in previous reports, were that RMS occurred in small-sized fish and accompanied mortality. Additionally, the presence of the Rickettsia agent was accompanied with outbreak of the disease. Therefore, this is the first report of RMS outbreak in rainbow trout fisheries in Korea.
Alkaloid Enantiomers from the Roots of Isatis indigotica
Authors: Zhang Dongdong , Shi Yanhong , Xu Rui , Du Kang , Guo Fujiang , Chen Kaixian , Li Yiming , Wang Rui
Published: August 2019

Five pairs of alkaloid enantiomers (1a/1b–5a/5b) were obtained from Isatis indigotica (I. indigotica) roots. Among them, 1a/1b, 2a/2b and 3a/3b were determined as three pairs of new alkaloid enantiomers. Their structures were elucidated by physicochemical properties and spectroscopic methods. The absolute configurations were deduced by comparison of their experimental circular dichroism (CD) and calculated electronic circular dichroism (ECD) spectra, as well as by single-crystal X-ray crystallography using anomalous scattering of Cu Kα radiation. Alkaloids 1a and 1b possess an unpresented carbon skeleton and their putative biosynthetic pathways are discussed. Moreover, all of the alkaloids were tested for their nitric oxide (NO) inhibitory effects in RAW 264.7 cells, and 4a and 4b showed inhibitory effects with IC50 values of 76.97 μM and 65.88 μM, respectively.
Converging Fate of the Oxidation and Reduction of 8-Thioguanosine
Authors: Taras-Goslinska Katarzyna , Vetica Fabrizio , Barata-Vallejo Sebastián , Triantakostanti Virginia , Marciniak Bronisław , Chatgilialoglu Chryssostomos
Published: August 2019

Thione-containing nucleobases have attracted the attention of the scientific community for their application in oncology, virology, and transplantology. The detailed understanding of the reactivity of the purine derivative 8-thioguanosine (8-TG) with reactive oxygen species (ROS) and free radicals is crucial for its biological relevance. An extensive investigation on the fate of 8-TG under both reductive and oxidative conditions is here reported, and it was tested by employing steady-state photooxidation, laser flash photolysis, as well as γ-radiolysis in aqueous solutions. The characterization of the 8-TG T1 excited state by laser flash photolysis and the photooxidation experiments confirmed that singlet oxygen is a crucial intermediate in the formation of the unexpected reduced product guanosine, without the formation of the usual oxygenated sulfinic or sulfonic acids. Furthermore, a thorough screening of different radiolytic conditions upon γ-radiation afforded the reduced product. These results were rationalized by performing control experiments in the predominant presence of each reactive species formed by radiolysis of water, and the mechanistic pathway scenario was postulated on these bases.
The Impact of Temperature and Ethanol Concentration on the Global Recovery of Specific Polyphenols in an Integrated HPLE/RP Process on Carménère Pomace Extracts
Authors: Huaman-Castilla Nils Leander , Martínez-Cifuentes Maximiliano , Camilo Conrado , Pedreschi Franco , Mariotti-Celis María , Pérez-Correa José Ricardo
Published: August 2019

Sequential extraction and purification stages are required to obtain extracts rich in specific polyphenols. However, both separation processes are often optimized independently and the effect of the integrated process on the global recovery of polyphenols has not been fully elucidated yet. We assessed the impact of hot-pressurized liquid extraction (HPLE) conditions (temperature: 90–150 °C; ethanol concentration: 15%–50%) on the global recovery of specific phenolic acids, flavanols, flavonols and stilbenes from Carménère grape pomace in an integrated HPLE/resin purification (RP) process. HPLE of phenolic acids, flavanols and stilbenes were favored when temperature and ethanol concentration increased, except for chlorogenic acid which showed an increment of its Gibbs free energy of solvation at higher ethanol contents. Ethanol concentration significantly impacted the global yield of the integrated HPLE/RP process. The lower the ethanol content of the HPLE extracts, the higher the recovery of phenolic acids, flavanols and stilbenes after RP, except for flavonols which present more polar functional groups. The best specific recovery conditions were 150 °C and ethanol concentrations of 15%, 32.5% and 50% for phenolic acids, flavanols and stilbenes, and flavonols, respectively. At 150 °C and 32.5% of ethanol, the extracts presented the highest total polyphenol content and antioxidant capacity. The integrated HPLE/RP process allows a selective separation of specific polyphenols and eliminates the interfering compounds, ensuring the safety of the extracts at all evaluated conditions.
Zwitterionic Acetylated Cellulose Nanofibrils
Authors: Rostami Jowan , Mathew Aji P. , Edlund Ulrica
Published: August 2019

A strategy is devised to synthesize zwitterionic acetylated cellulose nanofibrils (CNF). The strategy included acetylation, periodate oxidation, Schiff base reaction, borohydride reduction, and a quaternary ammonium reaction. Acetylation was performed in glacial acetic acid with a short reaction time of 90 min, yielding, on average, mono-acetylated CNF with hydroxyl groups available for further modification. The products from each step were characterized by FTIR spectroscopy, ζ-potential, SEM-EDS, AFM, and titration to track and verify the structural changes along the sequential modification route.
Aggregation-Morphology-Dependent Electrochemical Performance of Co3O4 Anode Materials for Lithium-Ion Batteries
Authors: Kong Linglong , Wang Lu , Sun Deye , Meng Su , Xu Dandan , He Zaixin , Dong Xiaoying , Li Yongfeng , Jin Yongcheng
Published: August 2019

The aggregation morphology of anode materials plays a vital role in achieving high performance lithium-ion batteries. Herein, Co3O4 anode materials with different aggregation morphologies were successfully prepared by modulating the morphology of precursors with different cobalt sources by the mild coprecipitation method. The fabricated Co3O4 can be flower-like, spherical, irregular, and urchin-like. Detailed investigation on the electrochemical performance demonstrated that flower-like Co3O4 consisting of nanorods exhibited superior performance. The reversible capacity maintained 910.7 mAh·g−1 at 500 mA·g−1 and 717 mAh·g−1 at 1000 mA·g−1 after 500 cycles. The cyclic stability was greatly enhanced, with a capacity retention rate of 92.7% at 500 mA·g−1 and 78.27% at 1000 mA·g−1 after 500 cycles. Electrochemical performance in long-term storage and high temperature conditions was still excellent. The unique aggregation morphology of flower-like Co3O4 yielded a reduction of charge-transfer resistance and stabilization of electrode structure compared with other aggregation morphologies.
Study of Methionine Choline Deficient Diet-Induced Steatosis in Mice Using Endogenous Fluorescence Spectroscopy
Authors: Valor Alma , Arista Romeu Eduardo J. , Escobedo Galileo , Campos-Espinosa Adriana , Romero-Bello Ivette Irais , Moreno-González Javier , Fabila Bustos Diego A. , Stolik Suren , de la Rosa Vázquez Jose Manuel , Guzmán Carolina
Published: August 2019

Non-alcoholic fatty liver disease is a highly prevalent condition worldwide that increases the risk to develop liver fibrosis, cirrhosis, and hepatocellular carcinoma. Thus, it is imperative to develop novel diagnostic tools that together with liver biopsy help to differentiate mild and advanced degrees of steatosis. Ex-vivo liver samples were collected from mice fed a methionine-choline deficient diet for two or eight weeks, and from a control group. The degree of hepatic steatosis was histologically evaluated, and fat content was assessed by Oil-Red O staining. On the other hand, fluorescence spectroscopy was used for the assessment of the steatosis progression. Fluorescence spectra were recorded at excitation wavelengths of 330, 365, 385, 405, and 415 nm by establishing surface contact of the fiber optic probe with the liver specimens. A multi-variate statistical approach based on principal component analysis followed by quadratic discriminant analysis was applied to spectral data to obtain classifiers able to distinguish mild and moderate stages of steatosis at the different excitation wavelengths. Receiver Operating Characteristic (ROC) curves were computed to compare classifier’s performances for each one of the five excitation wavelengths and steatosis stages. Optimal sensitivity and specificity were calculated from the corresponding ROC curves using the Youden index. Intensity in the endogenous fluorescence spectra at the given wavelengths progressively increased according to the time of exposure to diet. The area under the curve of the spectra was able to discriminate control liver samples from those with steatosis and differentiate among the time of exposure to the diet for most of the used excitation wavelengths. High specificities and sensitivities were obtained for every case; however, fluorescence spectra obtained by exciting with 405 nm yielded the best results distinguishing between the mentioned classes with a total classification error of 1.5% and optimal sensitivities and specificities better than 98.6% and 99.3%, respectively.
Effects of Polar Steroids from the Starfish Patiria (=Asterina) pectinifera in Combination with X-Ray Radiation on Colony Formation and Apoptosis Induction of Human Colorectal Carcinoma Cells
Authors: Malyarenko Olesya S. , Malyarenko Timofey V. , Kicha Alla A. , Ivanchina Natalia V. , Ermakova Svetlana P.
Published: August 2019

Despite significant advances in the understanding, prevention, and treatment of cancer, the disease continues to affect millions of people worldwide. Chemoradiation therapy is a rational approach that has already proven beneficial for several malignancies. However, the existence of toxicity to normal tissue is a serious limitation of this treatment modality. The aim of the present study is to investigate the ability of polar steroids from starfish Patiria (=Asterina) pectinifera to enhance the efficacy of radiation therapy in colorectal carcinoma cells. The cytotoxic activity of polar steroids and X-ray radiation against DLD-1, HCT 116, and HT-29 cells was determined by an MTS assay. The effect of compounds, X-ray, and their combination on colony formation was studied using the soft agar method. The molecular mechanism of the radiosensitizing activity of asterosaponin P1 was elucidated by western blotting and the DNA comet assay. Polar steroids inhibited colony formation in the tested cells, and to a greater extent in HT-29 cells. Asterosaponin P1 enhanced the efficacy of radiation and, as a result, reduced the number and size of the colonies of colorectal cancer cells. The radiosensitizing activity of asterosaponin P1 was realized by apoptosis induction through the regulation of anti- and pro-apoptotic protein expression followed by caspase activation and DNA degradation.
Nonlocal Scalar Quantum Field Theory—Functional Integration, Basis Functions Representation and Strong Coupling Expansion
Authors: Bernard Matthew , Guskov Vladislav A. , Ivanov Mikhail G. , Kalugin Alexey E. , Ogarkov Stanislav L.
Published: August 2019

Nonlocal quantum field theory (QFT) of one-component scalar field φ in D-dimensional Euclidean spacetime is considered. The generating functional (GF) of complete Green functions Z as a functional of external source j, coupling constant g and spatial measure d μ is studied. An expression for GF Z in terms of the abstract integral over the primary field φ is given. An expression for GF Z in terms of integrals over the primary field and separable Hilbert space (HS) is obtained by means of a separable expansion of the free theory inverse propagator L ^ over the separable HS basis. The classification of functional integration measures D φ is formulated, according to which trivial and two nontrivial versions of GF Z are obtained. Nontrivial versions of GF Z are expressed in terms of 1-norm and 0-norm, respectively. In the 1-norm case in terms of the original symbol for the product integral, the definition for the functional integration measure D φ over the primary field is suggested. In the 0-norm case, the definition and the meaning of 0-norm are given in terms of the replica-functional Taylor series. The definition of the 0-norm generator Ψ is suggested. Simple cases of sharp and smooth generators are considered. An alternative derivation of GF Z in terms of 0-norm is also given. All these definitions allow to calculate corresponding functional integrals over φ in quadratures. Expressions for GF Z in terms of integrals over the separable HS, aka the basis functions representation, with new integrands are obtained. For polynomial theories φ 2 n , n = 2 , 3 , 4 , … , and for the nonpolynomial theory sinh 4 φ , integrals over the separable HS in terms of a power series over the inverse coupling constant 1 / g for both norms (1-norm and 0-norm) are calculated. Thus, the strong coupling expansion in all theories considered is given. “Phase transitions” and critical values of model parameters are found numerically. A generalization of the theory to the case of the uncountable integral over HS is formulated—GF Z for an arbitrary QFT and the strong coupling expansion for the theory φ 4 are derived. Finally a comparison of two GFs Z , one on the continuous lattice of functions and one obtained using the Parseval–Plancherel identity, is given.
Progress in Photonic-Crystal Surface-Emitting Lasers
Authors: Ishizaki Kenji , De Zoysa Menaka , Noda Susumu
Published: August 2019

Photonic-crystal surface-emitting lasers (PCSELs) have attracted considerable attention as a novel semiconductor laser that surpasses traditional semiconductor lasers. In this review article, we review the current progress of PCSELs, including the demonstration of large-area coherent oscillation, the control of beam patterns, the demonstration of beam steering, and the realization of watt-class and high-beam-quality operation. Furthermore, we show very recent progress in the exploration of high brightness of more than 300 MW cm−2 sr−1, obtained with a high output power of about 10 W while maintaining a high beam quality M2 ~ 2. The PCSELs with such high performances are expected to be applied to a variety of fields, such as laser-based material processing, optical sensing (light-detection and ranging (LiDAR)), and lighting, as they retain the benefits of compact and high-efficiency semiconductor lasers.
Insertional Mutagenesis Approaches and Their Use in Rice for Functional Genomics
Authors: Ram Hasthi , Soni Praveen , Salvi Prafull , Gandass Nishu , Sharma Ankita , Kaur Amandeep , Sharma Tilak Raj
Published: August 2019

Insertional mutagenesis is an indispensable tool for engendering a mutant population using exogenous DNA as the mutagen. The advancement in the next-generation sequencing platform has allowed for faster screening and analysis of generated mutated populations. Rice is a major staple crop for more than half of the world’s population; however, the functions of most of the genes in its genome are yet to be analyzed. Various mutant populations represent extremely valuable resources in order to achieve this goal. Here, we have reviewed different insertional mutagenesis approaches that have been used in rice, and have discussed their principles, strengths, and limitations. Comparisons between transfer DNA (T-DNA), transposons, and entrapment tagging approaches have highlighted their utilization in functional genomics studies in rice. We have also summarised different forward and reverse genetics approaches used for screening of insertional mutant populations. Furthermore, we have compiled information from several efforts made using insertional mutagenesis approaches in rice. The information presented here would serve as a database for rice insertional mutagenesis populations. We have also included various examples which illustrate how these populations have been useful for rice functional genomics studies. The information provided here will be very helpful for future functional genomics studies in rice aimed at its genetic improvement.
A Validation of Fengyun4A Temperature and Humidity Profile Products by Radiosonde Observations
Authors: He Min , Wang Donghai , Ding Weiyu , Wan Yijing , Chen Yonghang , Zhang Yu
Published: August 2019

Fengyun4A is the first geostationary satellite with payload of the infrared hyperspectral sounder. The geostationary platform-based instrument can provide observational 3-dimensional fields of temperature and humidity with high scanning frequencies and spatial resolutions. The IR instrument-observed temperature (T) and relative humidity (RH) profiles are closely related to the cloud states. Radiosonde observations are used to validate the Fengyun4A T and RH profiles under different cloud-type sky conditions. The cloud-type information comes from the Himawari-8 satellite which has substantial observing overlap with Fengyun4A over Asia. Taking the radiosonde observation as the reference, Fengyun4A T profile has uncertainty of 2.1 K under clear sky, and 3.7 K under cloudy sky. When cloudy sky is divided into cloud-type skies, the categories have disparities in temperature biases, varying from positive to negative. It is found that most of cloud-type categories have uncertainties of 2.5–3.0 K. The RH profiles have an uncertainty of 18% under clear sky and 21% under cloudy sky in absolute value. On average, the RH biases show neural but positively biased at the dry side and negatively biased at the wet side in the scatter plot. The International Satellite Cloud Climatology Project (ISCCP) cloud type can help to extend the quality flag of the Fengyun4A temperature profile. The impacts from cloud types on IR sounding profiles should be considered in product development or applications.
A Temperature Plasmonic Sensor Based on a Side Opening Hollow Fiber Filled with High Refractive Index Sensing Medium
Authors: Zhao Lei , Han Haixia , Luan Nannan , Liu Jianfei , Song Li , Hu Yongsheng
Published: August 2019

A surface plasmon resonance temperature sensor based on a side opening hollow-core microstructured optical fiber is proposed in this paper. This design employs a gold nanowire to excite the plasmon mode, and can be easily filled with the sensing medium through the side opening of the fiber, which not only simplifies the fabrication of the sensor but can also use the high refractive index sensing medium. The coupling characteristics, sensing performance and fabrication tolerance of the sensor are analyzed by using the finite element method. The simulation results indicate that the maximum sensitivity is 3.21 nm/°C for the x-polarized core mode in the temperature range of 13.27–50.99 °C, and 4.98 nm/°C for the y-polarized core mode in the temperature range of 14.55–51.19 °C, when benzene is used as the sensing medium. The sensor also shows a good stability in the range of ±10% fabrication tolerance.
An Adaptive Wake-Up-Interval to Enhance Receiver-Based Ps-Mac Protocol for Wireless Sensor Networks
Authors: Adam Mohammed Sani , Por Lip Yee , Hussain Mohammad Rashid , Khan Nawsher , Ang Tan Fong , Anisi Mohammad Hossein , Huang Zhirui , Ali Ihsan
Published: August 2019

Many receiver-based Preamble Sampling Medium Access Control (PS-MAC) protocols have been proposed to provide better performance for variable traffic in a wireless sensor network (WSN). However, most of these protocols cannot prevent the occurrence of incorrect traffic convergence that causes the receiver node to wake-up more frequently than the transmitter node. In this research, a new protocol is proposed to prevent the problem mentioned above. The proposed mechanism has four components, and they are Initial control frame message, traffic estimation function, control frame message, and adaptive function. The initial control frame message is used to initiate the message transmission by the receiver node. The traffic estimation function is proposed to reduce the wake-up frequency of the receiver node by using the proposed traffic status register (TSR), idle listening times (ILTn, ILTk), and “number of wake-up without receiving beacon message” (NWwbm). The control frame message aims to supply the essential information to the receiver node to get the next wake-up-interval (WUI) time for the transmitter node using the proposed adaptive function. The proposed adaptive function is used by the receiver node to calculate the next WUI time of each of the transmitter nodes. Several simulations are conducted based on the benchmark protocols. The outcome of the simulation indicates that the proposed mechanism can prevent the incorrect traffic convergence problem that causes frequent wake-up of the receiver node compared to the transmitter node. Moreover, the simulation results also indicate that the proposed mechanism could reduce energy consumption, produce minor latency, improve the throughput, and produce higher packet delivery ratio compared to other related works.
Experimental and Numerical Investigation on the Ultimate Vertical Bearing Capacity of U-Shaped Girder with Damaged Web
Authors: Zhang Jingfeng , Jing Yuan , Li Pandao , Han Wanshui , Zhang Nan , Zhou Yunlai
Published: August 2019

U-shaped girder has been extensively used for its excellent adaptability in the urban railway transit system. As an open thin-walled structure, significant difference of working mechanism exists between U-shaped girder and conventional section girder (e.g., T section or box section). The thin-walled web plays significant role in the flexural performance of U type girder particularly. Moreover, severe collision may occur between the moving train and the girder, and subsequently results in the decrease of the structural bearing capacity. In this paper, a full-scale test was carried out to examine the ultimate bearing capacity and the failure mechanism of the U-shaped girder, and a refined numerical model was developed to simulate the damage evolution and the failure process. It was shown that the flexural failure occurred on the U-shaped girder under vertical loads. In addition, the ultimate bearing capacity of the structure under different web damage conditions (e.g., web damaged region or damaged range) was studied by applying the displacement based lateral load on the flange of the U-shaped girder to simulate the damage caused by accidental train collision. The numerical results have shown that the damaged web greatly affects the ultimate bearing capacity of U-shaped girder, more severe bearing capacity descending occurs around the middle span rather than the beam ends. The damaged range (length) of the web has less influence on the falling amplitude of bearing capacity. It can be concluded that the major reason accounting for the bearing capacity decrease is that the original section is weakened by the web damage, and consequently results in the buckling of the damaged web and lead to the total failure of the structure. It is recommended that the lateral resistant design for the web should be taken into consideration to ensure the operation safety of the urban railway transportation.
Narrow Band Solid-Liquid Composite Arrangements: Alternative Solutions for Phononic Crystal-Based Liquid Sensors
Authors: Mukhin Nikolay , Kutia Mykhailo , Oseev Aleksandr , Steinmann Ulrike , Palis Stefan , Lucklum Ralf
Published: August 2019

Periodic elastic composite structures attract great attention. They offer the ability to design artificial properties to advance the control over the propagation of elastic/acoustic waves. In previous work, we drew attention to composite periodic structures comprising liquids. It was shown that the transmission spectrum of the structure, specifically a well-isolated peak, follows the material properties of liquid constituent in a distinct manner. This idea was realized in several liquid sensor concepts that launched the field of phononic crystal liquid sensors. In this work we introduce a novel concept—narrow band solid-liquid composite arrangements. We demonstrate two different concepts to design narrow band structures, and show the results of theoretical studies and results of experimental investigations that confirm the theoretical predictions. This work extends prior studies in the field of phononic crystal liquid sensors with novel concepts and results that have a high potential in a field of volumetric liquid properties evaluation.
Data Transmission Efficiency in Bluetooth Low Energy Versions
Authors: Bulić Patricio , Kojek Gašper , Biasizzo Anton
Published: August 2019

One important aspect when choosing a Bluetooth Low Energy (BLE) solution is to analyze its energy consumption for various connection parameters and desired throughput to build an optimal low-power Internet-of-Things (IoT) application and to extend the battery life. In this paper, energy consumption and data throughput for various BLE versions are studied. We have tested the effect of connection interval on the throughput and compared power efficiency relating to throughput for various BLE versions and different transactions. The presented results reveal that shorter connection intervals increase throughput for read/write transactions, but that is not the case for the notify and read/write without response transactions. Furthermore, for each BLE version, the energy consumption is mainly dependable on the data volume. The obtained results provide a design guideline for implementing an optimal BLE IoT application.
Integration in the Organizational Environment of the Spanish National Police
Authors: Marcos Alexandra , Pérez-Llantada María del Carmen , Topa Gabriela
Published: August 2019

In the present study, a model of relations is tested between the dimensions of socialization, personal resources such as optimism and self-efficacy, and the resources obtained during integration into the organization such as social support or collective efficacy in the prediction of the attitudes and behaviors of the Spanish National Police. Participants were members of the Spanish National Police (N = 123). The findings confirm some of the hypotheses, although other findings are contrary to the predictions. The percentage of variance explained in the regression analyses varies between 48% of the variance of stress and 24% of the variance of task commitment. The findings open new lines of research for the future given the positive impact of human resource management on satisfaction and commitment at work, as well as job stress and excellent performance.
Charging Network Planning for Electric Bus Cities: A Case Study of Shenzhen, China
Authors: Lin Yuping , Zhang Kai , Shen Zuo-Jun Max , Miao Lixin
Published: August 2019

In 2017, Shenzhen replaced all its buses with battery e-buses (electric buses) and has become the first all-e-bus city in the world. Systematic planning of the supporting charging infrastructure for the electrified bus transportation system is required. Considering the number of city e-buses and the land scarcity, large-scale bus charging stations were preferred and adopted by the city. Compared with other EVs (electric vehicles), e-buses have operational tasks and different charging behavior. Since large-scale electricity-consuming stations will result in an intense burden on the power grid, it is necessary to consider both the transportation network and the power grid when planning the charging infrastructure. A cost-minimization model to jointly determine the deployment of bus charging stations and a grid connection scheme was put forward, which is essentially a three-fold assignment model. The problem was formulated as a mixed-integer second-order cone programming model, and a “No R” algorithm was proposed to improve the computational speed further. Computational studies, including a case study of Shenzhen, were implemented and the impacts of EV technology advancements on the cost and the infrastructure layout were also investigated.
Straw Stocks as a Source of Renewable Energy. A Case Study of a District in Poland
Authors: Marks-Bielska Renata , Bielski Stanisław , Novikova Anastasija , Romaneckas Kęstutis
Published: August 2019

Biomass is playing an increasingly important role as a source of renewable energy. The aim of this study has been to identify the potential applicability of straw from agricultural crops to generate energy within the district of Braniewo, in the province Warmia and Mazury, Poland. The study covered the years 2015 to 2017. Based on statistical data, and using appropriate equations and norms, the structure of crop production and the number of livestock in the mentioned district were analysed; the potential production volume of straw was estimated, from which the amount needed for animal production (feed and bedding) was deducted, while the organic substance balance in soil was calculated. An annual average amount of straw remaining to be used for energy purposes in the district of Braniewo is about 41,531 t of straw, equivalent to about 60,222 GJ of energy (24,088 t of coal). In addition to the above analyses, a survey was conducted among local farmers, which showed their opinions about barriers to and opportunities for growing crops for energy purposes and using renewable energy resources. The survey results justify the claim that there is certain potential among farmers in the district of Braniewo to grow crops for energy purposes.
Optimization Method for Reducing the Air Pollutant Emission and Aviation Noise of Arrival in Terminal Area
Authors: Tian Yong , Wan Lili , Ye Bojia , Yin Runze , Xing Dawei
Published: August 2019

In order to reduce the environmental impact of aircraft operation in the terminal area, this paper researched the route optimization method. Firstly, this paper constructed the air pollutant emission and noise assessment model, and the flight performance model. Secondly, aiming at reducing air emissions and noise level, the multi-objective terminal area route optimization model is established based on the principles of flight safety and flight procedure construction. Then this paper puts forward the path optimization method of emission and noise reduction of terminal area route network, through the research on the priority setting method of terminal area approach and departure route planning. The route segmentation method and NSGA-II algorithm are employed to solve the problem. Finally, a numerical case study is carried out for the Shanghai terminal area, and yields the following results: (1) Compared with the original route network, the optimized route network in the terminal area can significantly reduce emission and noise by reducing pollutant emission by 51.4% and noise influence by 21.5%; (2) The method can also reduce fuel consumption by 60.5% and the total route length by 21.1%.
Aplikasi Pendaftaran Rawa BaTIK (Ruang Aktivitas Warga Belajar Aplikasi dan TIK) Berbasis Web
Authors: Rifani Much , Permadi Jaka
Published: August 2019

Dinas Komunikasi dan Informatika (DISKOMINFO) Kabupaten Tanah Bumbu memiliki program yang sedang digiatkan yaitu Ruang Aktivitas Warga Belajar Aplikasi dan TIK (Rawa BaTIK). Program tersebut bertujuan untuk memberikan kesempatan bagi pelajar dan masyarakat untuk dapat belajar TIK di pusat study DISKOMINFO. Permasalahan yang muncul yaitu calon peserta harus mendaftar langsung di kantor DISKOMINFO, dimana lokasi pendaftaran tersebut cukup jauh dari pusat kota. Berdasarkan permasalahan tersebut dibangunlah aplikasi pendaftaran Rawa BaTIK berbasis web. Aplikasi tersebut dibangun dengan menggunakan model waterfall, dimana perancangannya menggunakan ERD, DFD dan flowchart, dan bahasa pemrograman yang digunakan adalah HTML, PHP dan JavaScript. Aplikasi tersebut sudah diuji menggunakan metode Black Box Testing dengan hasil pengujian menunjukkan bahwa semua fungsionalitas dari aplikasi pendaftaran Rawa BaTIK berjalan seluruhnya.
Aplikasi Augmented Reality (AR) Alur Pembuatan SIM C Berbasis Android
Authors: Supriyanto Arif , Asmilia Asmilia
Published: August 2019

Augmented Reality (AR) merupakan teknologi yang menggabungkan benda maya dua dimensi dan tiga dimensi lalu memproyeksikan benda-benda maya tersebut kedalam dunia nyata. Teknologi AR dapat diterapkan untuk media informasi. Khususnya pada Android yang memiliki banyak pengguna dari kalangan masyarakat di Indonesia. Tujuan dari dibangunnya aplikasi AR  alur pembuatan SIM C berbasis Android ini adalah untuk memberikan informasi yang yang lebih menarik dan interaktif kepada masyarakat tentang alur pembuatan SIM C. Melalui media informasi ini masyarakat dapat berinteraksi langsung dengan aplikasi AR untuk mengetahui alur pembuatan dan juga persyaratan pembuatan SIM C dengan lebih menarik dan mudah dimengerti. Aplikasi yang dibangun menampilkan objek virtual 3D dan audio pada perangkat mobile android secara real time. Berdasarkan hasil pengujian aplikasi ini dapat bekerja dengan baik pada mobile platform android dan hasil uji coba implementasi berdasarkan kuisioner sebanyak 30 orang menggunakan metode skala likert diperoleh hasil 80,66%. Maka dapat disimpulkan aplikasi AR alur pembuatan SIM C berbasis android ini dikategorikan sangat baik.
Estimasi Perbandingan Efisiensi Saham di Perusahaan Industri menggunakan Metode Dea Solver dengan Model CCR
Authors: Fitriyani Yuli , Kamil Insan
Published: August 2019

Penelitian ini menggunakan metode Data Empelopment Analysis (DEA) yang merupakan sebuah metode kuantitatif non parametik yang dapat digunakan untuk menganalisis kinerja ataupun untuk menilai tingkat efisiensi dan membandingkannya dari setiap Decision Making Unit (DMU). DMU dinyatakan sudah mencapai tingkat efisiensi relatif jika sudah mencapai nilai 1 atau 100% dan semakin tidak efisiensi jika semakin jauh dari nilai 1 atau 100%. Penelitian ini untuk menganalisis efisiensi perusahaan makanan dan minuman di Indonesia menggunakan metode DEA dengan model CCR. Model CCR atau (Charner, Cooper, dan Rhodes) dimana metode DEA Solver ini biasanya digunakan untuk menilai tingkat efisiensi relatif dengan terlebih dahulu menentukan karakteristik dari setiap katagori atau DMU tersebut. Hasil dari penelitian tersebut menunjukan bahwa terdapat 2 DMU yang memiliki tingkat efisiensi 1 dan 3 DMU yang tidak efisiensi.
NIVEL DE SATISFACCIÓN LABORAL DEL PERSONAL DEL POLICLÍNICO AZÁNGARO-ESSALUD
Authors: Frisancho Magaly
Published: August 2019

El objetivo del estudio fue determinar el nivel de satisfacción laboral  del  personal del Policlínico   Azángaro- EsSalud, tomando en consideración que esto es considerado un factor importante en el desempeño laboral. Método: fueron evaluados   56 individuos, todos trabajadores del policlínico Azangaro, perteneciente a la Red Asistencial Juliaca- para ello se empleó la técnica  de entrevista estructurada directa, dutos datos fueron registardos en una ficha  específicamente  diseñada y validada para este propósito.
MOVIMIENTO DENTAL ACELERADO ME DIANTE FUERZAS VIBRATORIAS (ACCELEDENT®) EN TRATAMIENTO S ORTODÓNTICOS CONTEMPORÁNEOS LLEVADA A LA PRÁCTICA DIARIA
Authors: Mercado Sively , Carreón Brifhel , Zapana Nohely
Published: August 2019

La ortodoncia contemporánea tiene como objetivos establecer función, estética, estabilidad e integridad de los tejidos de soporte, el ortodoncista obtiene estos objetivos a través de los conocimientos, filosofías, mecánicas o formas de tratamiento. A través de la ciencia y la tecnología, se ha logrado complementar al tratamiento usual, mejoras para la comodidad y el bienestar del paciente, una de estas mejoras ha sido el movimiento dental acelerado, cuya ventaja es reducir el tiempo del tratamiento ortodóntico, escapando a la incomodidad estética, la limitación en la dieta y en la limpieza bucal, lo que significaría reducir el riesgo de caries o enfermedad periodontal.Existen en la actualidad diversos tratamientos para la aceleración del movimiento dental en la ortodoncia, así las corticotomí as, fármacos etc,que en algunos casos tienen efectos secundarios y son considerados tratamientos invasivos Sin embargo, el AcceleDent®, sistema de microvibraciones es uno de los métodos más eficaces y poco invasivos que existen para acelerar el movimiento de los dientes. Nuestro objetivo es describir la evidencia científica actual de los inicios del AcceleDent®, eficacia, ventajas y desventajas, con la expectativa de poder indicar su uso en futuros tratamientos con resultados óptimos reduciendo el tiempo de tratamiento incomodidades y riesgos.
LA IMPORTANCIA DE LOS ESTUDIOS DESCRIPTIVOS
Authors: Villavicencio Ebingen
Published: August 2019

NO CORRESPONDE
INFLUENCIA DEL EDENTULISMO PARCIAL EN EL ESTADO NUTRICIONAL EN PACIENTES GERIATRICOS ATENDIDOS EN JULIACA
Authors: Machaca Leonel , Baylón Cynthia
Published: August 2019

Introducción: El presente trabajo de investigación se realizó con el objetivo de describir y analizar el papel del edentulismo parcial como factor de riesgo en el estado nutricional en pacientes geriátricos atendidos en el establecimiento de salud Vilcapata de Juliaca. Métodos: El estudio se llevó a cabo en una muestra de 120 pacientes geriátricos, realizándose un muestreo no probabilístico intencional, ejecutando una estricta selección de los casos según los criterios establecidos por el investigador; se llevó a cabo una encuesta y observación clínica a ﬁn de recolectar los datos de interés del estudio. Resultados: Tras analizar los datos recolectados se encontró que el tipo de edentulismo parcial más frecuente en el maxilar superior fue el de Clase I presente en el 31.7% de los pacientes evaluados; con respecto al maxilar inferior, lo más frecuente fue el edentulismo total en un 36.7%. En lo referente a la técnica de cepillado el 43.3% manifestó no tener conocimiento sobre la manera adecuada de hacerla; mientras que sobre la frecuencia de cepillado el 45.8% expresó no hacerlo a diario. El 42.5% presentó un estado nutricional normal y un 5.0% de delgadez severa. Conclusión: El edentulismo parcial es una de las consecuencias de no cuidar la salud oral, este síndrome es la ausencia o la pérdida parcial de los dientes; este factor se presenta como factor de riesgo determinante en el estado nutricional en pacientes geriátricos atendidos.
RELACIÓN DEL NIVEL DE ANSIEDAD Y EL TIPO CONDUCTA DURANTE EL TRATAMIENTO ODONTOPEDIÁTRICO
Authors: Perez Miler
Published: August 2019

INTRODUCCIÓN: El presente trabajo de investigación tuvo como objetivo relacionar la ansiedad en el tratamiento dental con la conducta de los niños atendidos en la clínica odontológica de la Universidad Andina Néstor Cáceres Velásquez de Juliaca en el año 2014. MATERIALES Y METODO: El estudio fue de enfoque cuantitativo nivel de investigación correlacional y según la temporalidad transversal, se evaluó a los niños que asistieron a la clínica odontológica durante el periodo académico del 2014 II en niños de 7 a 11 años de edad. Del total de 500 niños atendidos se seleccionó una muestra de 77 niños. En la investigación se empleó el cuestionario de subescala dental del miedo infantil “Children's Fear Survey Schedule - Dental Subscale” (CFSS-DS) la cual permitió evaluar el nivel de ansiedad, la conducta se identiﬁcó mediante la escala de conducta de Frankl. RESULTADOS: Los niños que no tuvieron ansiedad dental presentaron conducta positiva con 55.00%, 35.00% tuvieron conducta deﬁnitivamente positiva; a diferencia de los niños con mucha ansiedad que su mayor porcentaje de 88.57% manifestaron una conducta deﬁnitivamente negativa. CONCLUSIONES: El grado de ansiedad tiene relación con la conducta en el tratamiento dental, los pacientes de sexo masculino presentan menos grados de ansiedad de 23.68% a diferencia de los pacientes de sexo femenino (66.67%).
SALUD BUCAL Y PASTA BÁSICA D E COCAÍNA EN PACIENTES HOSPITALIZADOS POR CONSUMO DE SUSTANCIAS PSICOACTIVAS PERÚ
Authors: Reyes Jorge , Palian Raúl , Ordóñez Carlos , Garcia Victor
Published: August 2019

El trabajo de investigación se desarrollo en forma conjunta entre el Servicio de hospitalización del departamento de Adicciones y el serviciode Odontoestomatología del Hospital Hermilio Valdizan en Lima Perú. Con el objetivo de conocer el estado de la salud oral en pacienteshospitalizados consumidores de pasta básica de cocaína y otras sustancias psicoactivas en un hospital psiquiátrico. Material y Método: Elestudio fue clínico, observacional, descriptivo, transversal; tomando como muestra los pacientes consumidores de sustancias psicoactivashospitalizados en pabellón 6 varones, en el periodo de julio 2011-diciembre 2012. Se realizo una encuesta socio demográfica, una fichade captación de datos de estudio en pacientes dependientes de sustancias psicoactivas de Ordóñez, los índices CPOD de Klein y Palmer,IHOS de Green y Vermillon, de Erosión dental de Eccles y Jenkins. El 44% se encontraba en edades de 15 a 25 años. Las diferentespatologías orales en pacientes consumidores de sustancias psicoactivas están relacionadas al descuido personal y abandono socialproducto de su conducta adictiva. En donde el 56% consume PBC y un 95% alcohol. Los investigadores han reportado una alta incidenciaen caries dental 97%, enfermedades periodontales 94%, y un edentulismo parcial o total 62%.
COMPARACIÓN DEL CEFALOGRAMA DE STEINER Y TATIS EN LA DETERMINACIÓN DEL PATRÓN ESQUELETAL
Authors: Cutipa Willy
Published: August 2019

Introducción: El éxito del tratamiento está en realizar un correcto diagnóstico, el cual está basado en el análisis de la historia clínica, modelosde estudio, fotografías y estudio de cefalometría .El advenimiento de la cefalometría marcó el fin de una era y el inicio de otra, al permitirnosconocer y medir un gran número de variables que permanecieron ocultas hasta el momento. Desde entonces el diagnóstico del caso ortodónticocomprende dos aspectos claramente diferenciados: el clínico y el cefalométrico. Materiales y Métodos; la muestra consistió en 80 radiografías(40 panorámicas y 40 laterales de cráneo) de pacientes que acudieron a la clínica de ortodoncia del Hospital Militar Central. Todos los pacientesson de origen peruano con un rango de edad 12-16 años. Una vez tomadas la radiografía panorámica y lateral de cráneo, se procdeió adeterminar el patrón esqueletal trazando la radiografía lateral de cráneo con el análisis cefalométrico de Steiner. Posteriormente se continuócon el trazado cefalométrico de la radiografía panorámica propuesto por TATIS, se usó la prueba estadística T-Student.Resultados; En comparación, NO existe coincidencia entre los resultados obtenidos del análisis cefalométrico de STEINER y TATI S en granparte del grupo muestra. Conclusiones; En cuanto a los datos obtenidos de la clase esqueletal, presentaron diferencias de coincidencia entrelos resultados obtenidos del análisis cefalométrico de Steiner y Tatis en todo el grupo, probando según este valor la dudosa c onfiabilidad delanálisis de Tatis para determinar la clase esqueletal, pero análisis cefalométrico de Tatis junto al de Steiner unido pueden formar una unidadde diagnóstico más amplia.
TRATAMIENTO ORTODÓNTICO INVISIBLE MEDIANTE INVISALIGN: REVISIÓN DE LITERATURA BASADA EN EVIDENCIA
Authors: Rojas Rosalynn , Fernández Armando , Solis Gilmer
Published: August 2019

La técnica Invisalign creada para satisfacer las necesidades estéticas de pacientes adultos que se niegan a tratamientos convencionales. Este novedoso tratamiento inició con el Dr. Kesling en 1945, recibiendo posterior impulso con Ponitz y McNamara. El sistema de invisalign, el cual ha surgido en los últimos años de la mano de Align Technology en 1997, ha demostrado ser una alternativa novedosa, y efectiva par a la corrección de las maloclusiones; el sistema está compuesto de aparatos plásticos transparentes que generan movimientos dentales de aproxi madamente de 2-3mm. El sistema requiere la planificación virtual y la simulación del tratamiento, lo que permite analizar desde todos los ángulos posibles, y con diferentes vistas, las modificaciones necesarias a realizar. La estética del sistema es una gran ventaja ante pacientes con dudas de aceptación al tratamiento. Al planificar un tratamiento ortodóntico debemos considerar diversos aspectos de forma multidisciplinaria, tales como: el estado periodontal, ausencia de piezas dentales (con o sin necesidad de implantes), etc. Este artículo recopila la información del sistema Invisalign,desde las indicaciones, contraindicaciones, ventajas y desventajas; basadas en evidencia, lo que le permita al clínico identif icar su aplicación clínica, según los requerimientos de cada caso.