bluuebunny/crossref_metadata_2025 huggingface dataset:
Aspects of rehabilitation of disabled elderly persons in the Russian Federation
Authors: Puzin S. N , Shurgaya Marina A. , Shkurko M. A , Krasnomyasova I. A , Khristophorov S. N , Memetov S. S
Published: September 2020

The article presents the results of the study of recommendations both for the rehabilitation of citizens, recognized primary and re-examination as disabled patients in the Russian Federation (2014). A positive result of the implementation of individual rehabilitation program was achieved in 45.1% of persons with disabilities, with the most significant recovery rates being at the level of 51.7% (integration of disabled persons in the family and society) and 50.8% (achievement of a partial compensation of lost functions). Disturbed functions were partially restored in 28.6% ofpersons with disabilities. As a result of the analysis of questionnaires of the evaluation tool (308forms), performed in the Care Home of Labor Veterans number 17, the Department of Labor and Social Protection of Moscow, there was revealed the medical and social status of persons with disabilities staying in this institution. The gender structure ofpersons with disabilities is characterized by a slight predominance ofwomen (59.7%) versus 40.3% of men. Among of all persons with disabilities there are dominated people aged of 75-89 years (51.9%). In the implementation of the comprehensive rehabilitation of disabled patients the need in drug therapy accounts of 100%, in the physiotherapy treatment - 89.6%, and physical therapy methods are used in 99.4% ofpersons with disabilities. With bearing in mind medical indications there are applied methods of socio-environmental, social and domestic, socio-psychological, sociocultural (art therapy, library therapy and adaptive physical education). For the creation of a barrier-free environment patients with disabilities are provided with the technical means of Rehabilitation. At the end of 2014 16.0 thousand people stand on the waiting list for the admission in stationary social care institutions for adults in the Russian Federation. With taking into account of demographical situation of an aging of the population and the gain in the demand for stationary establishments [2] intended for living of the older generation of people who cannot take care of themselves independently and need constant assistance, the further development of the social service system is feasible and has an important medical health value.
Prosthetics in complex medical and social rehabilitation of patients with ocular pathology
Authors: Verigo Elena N. , Makarov P. V
Published: September 2020

There is presented an analysis of results of observations in patients underwent different ocular prosthetic procedures: 152 patients with keratoprosthesis; 5456 cases with congenital or acquired anophthalmia, microphthalmus and ocular subatrophy with ocular prosthesis and 63 patients with ecto prosthesis. There are considered clinical, organization and legal aspects of indications for different prosthetic procedures, possible complications and their prevention. There was determined the role ofprosthetics in rehabilitation and medico-social adaptation in patients with severe ocular pathology which helps to improve the quality of life and rehabilitation ofpatients in dependence on their age, kind of the occupational activity and psychosomatic state.
FALL IN ELDERLY PATIENTS, ASSOCIATED WITH THE USE OF MEDICINES: CLINICAL OBSERVATION
Authors: Ilina Ekaterina S. , Sychev D. A , Bogova O. T
Published: September 2020

The article presents an analysis of a clinical case of a female patient D., aged of 93 years, hospitalized in the cardiology department of the hospital with multimorbidity and polypragmasy, who had the fall episode due to the prescription of midazolam administered parenterally. The fall was accompanied by the development of trauma - bruising her forehead, followed by suppuration, which demanded surgery in a surgical department. In this clinical case, the fall was a predictor of adverse drug reactions associated with the prescription of the drug preparation.
OLDER GENERATION: MEDICAL AND SOCIAL PROBLEMS
Authors: Shurgaya Marina A. , Memetov S. S , Silenko L. V
Published: September 2020

In an article there are presented results of a sociological survey of elderly people who underwent inpatient treatment at the State Budget Institution «Hospital for Veterans of Wars» in the Rostov Region in 2016. The survey was implemented according to a specially developed questionnaire. The respondents included 220 cases of elderly and senile age. The results of the survey showed the majority of elderly respondents, including disabled people, as to mention the main problems of elderly people as health problems and access to medical care as note a high level of anxiety.
LEGISLATIVE AND STANDARD AND METHODICAL BASE OF THE STANDARDIZATION, ASSESSMENT OF THE COMPLIANCE AND ACCREDITATION IN AREAS OF MEDICAL PRODUCTS
Authors: Ivanova Valeriya A. , Chesnokova A. A , Shamina E. O
Published: September 2020

The standard and methodical documents regulating activity in the field of standardization, estimates of compliance, accreditation of bodies for a compliance assessment in the field of medical products are submitted. The list of participants of works and documents in the field of standardization of medical products is provided, forms of an assessment of compliance of medical products - certification, compliance declaring, the state registration, technical tests are characterized. Requirements to contents of necessary documentation and an order of accreditation of testing laboratories in the field of medical products are established.
CLINICAL AND EXPERT EVALUATION OF PERSISTENT DISTURBANCES OF FUNCTIONS IN BREAST CANCER
Authors: Sklyarenko R. T , Dovgalyuk A. Z , Spiridonova Vera S.
Published: September 2020

There is proposed clinical expert and quantitative evaluation of persistent disorders of body functions with taking into account the TNM classification and prognostic factors in breast cancer patients.
NOSOLOGICAL SPECTRUM OF THE DISABILITY IN THE ELDERLY POPULATION OF THE ELDERLY CATEGORY IN THE RUSSIAN FEDERATION AND PECULIARITIES OF REHABILITATION-EXPERT DIAGNOSTICS, REHABILITATION AND ABILITATION
Authors: Shurgaya Marina A.
Published: September 2020

Disability of the elderly age group of the population is the most important problem of public health and social services of all developed countries over the world without exception. In the Russian Federation, this age segment is characterized by the gain, reflecting the global process of population aging. The aim of the study was to analyze the nosological structure of the primary and secondary disability in elderly people in comparison with the main age categories of the adult population in the Russian Federation and the evaluation of rehabilitation / rehabilitation activities for disabled people. The volume of the study was 34,840,933 people aged of from 18 years and over, recognized as disabled, including the disabled elderly - 12,971,062. The subject of a special study was the nature of functional disorders, the degree of the disability, the nosological spectrum of causes of the disability of elderly people and the effectiveness of implemented measures of medical and social rehabilitation (rehabilitation and expert characterization). The study was selective, the sample size account of 370 people. The results of the research demonstrate the nosological structure of the pathology, the associated types of impairments and the nature of the disability to determine the severity of the disability in elderly people, the complexity of the formation and implementation of individual programs for the rehabilitation and rehabilitation of disabled people (IPRA). The improvement of the quality of life and integrating disabled people into the society has been and remains a difficult task for rehabilitation and habilitation activities. Rehabilitation and provision of technical means of rehabilitation, to a lesser extent - social and professional rehabilitation are the most feasible for the implementation.
COMPARATIVE ANALYSIS OF AGE AND CLINICAL CHARACTERISTICS OF ALCOHOL DEPENDENT PATIENTS IN NARCOLOGICAL HOSPITALS OF THE TWO REGIONS OF THE REPUBLIC OF TAJIKISTAN
Authors: Sharopova Nigina M. , Krivoruchko Yu. D , Malikov N. V , Martiushov A. N
Published: September 2020

According to the preliminary analysis of the epidemiological data in various regions of Tajikistan, there were established differences in the dynamics of epidemiological indices. Based on this, a hypothesis about differences in the impact of biological and social factors on the increase of the risk of the developing alcohol dependence was proposed. The article analyzes age and related characteristics of patients enrolled in a drug treatment medical institutions of Dushanbe (100 observations) and Kurgan-Tyube (50 observations). Obtained results of the analysis showing the differences of the examined groups of patients can help not only to optimize the volume and nature of the specialized narcological help but also to form an idea of targeted preventive measures for different population groups.
Phenotypic variability of Trichomonas vaginalis as the cause of resistance to metronidazole
Authors: Syuch Natalie I. , Machkalyan K. E , Makhneva N. V
Published: September 2020

The results of the study of the nitrosoguanidine mutagen effect on phenotypic variability of Trichomonas vaginalis are presented. Formation of non flagellated protozoa is detected. The relationship between torpid and difficult to treat forms of urogenital trichomoniasis with the presence of amastigote (non flagellated) forms with simple changes in the genome that have a high potential for survival is described.
Assessment of dermatoheliosis with reflectance confocal microscopy
Authors: Snarskaya E. S , Tkachenko S. B , Kuznetsova Ekaterina V.
Published: September 2020

Dermatoheliosis increases the risk of developing malignant epithelial skin tumors and locates on aesthetically critical areas. Therefore there is a need for noninvasive objective technique capable of in vivo assessing the cumulative effect of UV-radiation, the severity ofphotoaging and the risk of epithelial skin cancer. In our study we aimed to determine the morphological changes occurring on photoaged skin and early signs of keratinocyte dysplasia by means of reflectance confocal microscopy (RCM). Material and method. The samples of facial skin of 40 volunteers from distinct groups, determined by Glogau scale (grades I-IV), have been examined with RCM. Results. The presence of irregular honeycomb pattern is increasing with progressing of dermatoheliosis. Mottled pigmentation and polycyclic papillary contours were determined in grade II-IV Glogau individuals, in the number of cases there were not demonstrated any pathological skin changes in analyzing area. Dermal structures are significantly transforming: reticulated collagen fibers are replacing with coarse collagen structures, huddled collagen and curled bright structures. RCM is capable of identifying early signs of sun damage and keratinocyte dysplasia in skin in the absence of any clinically visible symptoms.
Dependence of the microRNA profile in cutaneous melanoma on clinical and morphological characteristics of the tumor
Authors: Komina A. V , Palkina N. V , Aksenenko M. B , Ruksha Tatyana G.
Published: September 2020

Melanoma is an aggressive skin cancer that is characterized by rapid growth and high invasion. Today extensive studies of melanomagenesis allow to subdivide this tumor into subtypes in accordance to molecular, genetic and biochemical characteristics in addition to standard histological classification for developing personalized approaches of treatment. One ofsuch molecular peculiarities is the expression profile of microRNAs in tumor cells alterations of which were shown during tumor progression. The aim of this study was to identify the correlation between the levels ofmicroRNA in melanoma cells, and the clinical and morphological characteristics of the disease. The comparative study of microRNAs expression profiles in melanoma is made by gender, age ofpatients, tumor Breslow’s thickness and histological subtypes. It was shown that the gender and age ofpatients have no effect on the expression of microRNA in melanoma. No correlation between the microRNA levels and tumor Breslow’s thickness was revealed. But it was observed a significant alteration between the microRNA profiles in the different histological melanoma subtypes. The significant change in the profile of microRNAs for superficial-spreading melanomas compared to other subtypes was shown that was associated with the processes of tumors development, as well as ErbB-, MAPK-, TGF-β-signaling pathways. Further study of the molecularfeatures of the superficial-spreading melanoma in combination with other characteristics might be a new step towards personalized medicine.
Acne, the microbiome and innate immunity
Authors: Ionescu Marius-Anton A , Feuiolley M. , Enault J. , Wolkenstein P. , Robert G. , Lefeuvre L.
Published: September 2020

In the laste years several articles focalized on human microbioma - the microorganisms from skin, mucosae, bowel - and on its role in chronic inflammatory diseases of the skin as acne, rosacea, atopic dermatitis, seborrheic dermatitis. In this article the authors present an update on particular acne skin’s microbioma, on innate immunity in acne and new physiopathology mecanisms described in inflammatory process in acne, and at the end we present in vitro, ex vivo and in vivo studies on the microbioma modulation and microbiofilm of pathogenic ribotypes of P. acnes leading to a significant improvement of acne in a series of 74 acne patients.
Chronic spontaneous urticaria
Authors: Minkina Ekaterina V.
Published: September 2020

Urticaria is a common disorder. Urticaria ranks 3rd place in Russia after bronchial asthma and pollinosis. The incidence of the disease is 15.3-31%, with 41.3% of the chronic urticarial and 58.7% of the angioedema. The detection of cause of the disease and appropriate treatment is still a matter of some difficulties. The cause of the chronic spontaneous urticaria is not identified in 80-85%. The literature review of data on the main aspects of etiology, nosogenesis, diagnostic, international and local recommendations for the treatment of chronic spontaneous urticarial is presented.
Tick bite: clinical case report
Authors: Tarasenko Grigoriy N. , Vorozhko N. V , Kurilova E. A , Bekoeva A. V
Published: September 2020

The clinical case of flebotodermia, which has arisen on a sting of the tick, is presented. The patient consulted a dermatologist about irritable papilloma in the left armpit. With careful examination and dermoscopy was detected tick in the skin with symptoms of inflammatory reaction around the bite. The tick removal by electrocoagulation was performed. The authors draw the attention of doctors of all specialties on the needfor careful and regular inspection of patients in hospitals for the presence and remove of ticks.
Treatment of lymphangioma circumscriptum using copper vapor laser
Authors: Klyuchareva Svetlana V. , Nechaeva O. S , Belova E. A , Guseva S. V , Khabbus A. G , Ponomarev I. V
Published: September 2020

Vascular tumors occupy an important place among the benign tumors. Blood vessels tumors are studied and described in details, while there are few data about tumors of the lymphatic vessels in the literature and there are no methods of therapy. The aim of our work was to study the effectiveness of laser treatment methodfor patients with skin lymphangioma. By selective laser therapy copper vapor laser wavelength 578 nm has been selected. Patients received 1-2 treatments at 2 week intervals. The positive results were observed, efficacy was 100%, no recurrence registered. The use of copper vapor laser for treatment of lymphangioma with good cosmetic effect and long-lasting results is described.
General cryotherapy with the use of cryocapsule ICEQUEEN in patients with various dermatoses
Authors: Olisova Olga Yu. , Kayumova L. N , Smirnov K. V , Shuppo O. A , Arsentyev N. S
Published: September 2020

The article describes the modern approach to the treatment of chronic immune-mediated skin diseases using a new method of physiotherapy - general cryotherapy in cryocapsule ICEQUEEN. Combination standard treatment with drug-free and some non-drug therapies significantly improves the therapeutic effect that demonstrated in particular by the efficiency of cryotherapy. Talking about the efficiency of cryotherapy in many dermatoses authors refer not only to the literature data but also on their own experience. Pronounced clinical effect was noted in patients with psoriasis, atopic dermatitis, lichen planus, pruritus and toxiderma. Low efficiency was observed in the treatment of acne.
Mistakes of diagnostics in pemphigus vulgaris: case report
Authors: Khamaganova Irina V. , Malyarenko E. N , Denisova E. V , Vorontsova I. V , Plieva K. T
Published: September 2020

The causes for the fault diagnosis of pemphigus vulgaris are discussed. The lowering of the age of patients noted the last years, clinical peculiarities similar with those in other bullous dermatoses and toxic epidermal necrolysis and multiforme exudative erythema are considered. A case in a 35-year old man who was sequentially in different clinics diagnosed Exacerbation of chronic nasopharyngitis. aphthous stomatitis, Lacunar tonsillitis. oral thrush, Chemical burn of the mucosa of the oral cavity, Chemical burn of the esophagus. Erosive - ulcerative form of lichen ruber planus of the mucosa of the oral cavity, Multiforme exudative erythema is presented. According to the diagnosis different medicines were prescribed, any improvement was not noted The vulgar pemphigus was diagnosed in 2 months after the appearance of the first eruption.
Retrospective analysis of the most common sexually transmitted diseases in patients in a metropolis
Authors: Abuduev N. K , Plakhova K. I , Rubtsov A. B , Vasiliev M. M , Burtsev O. A , Katunin G. L
Published: September 2020

Objective: to evaluate the incidence of sexually transmitted infections (STIs), in patients of State Research Center of dermatology and cosmetology Russian Ministry of Health in comparison with indicators of morbidity in the Russian Federation. Material and methods. A retrospective analysis of the structure appeals to the department of infectious urogenital diseases of Russian Ministry of Health for the period from 2011 to 2015. Results. The result of the department of sexually transmitted infections of State Scientific Center for Dermatovenereology and Cosmetologymost frequently recorded patients with anogenital (venereal) warts, syphilis and chlamydial infection. Moreover, the majority of women (52%) identified inflammatory diseases of the vagina, vulva, cervix and changes cervical mucosa. It was found that in Moscow and among patients of State Scientific Center for Dermatovenereology and Cosmetology regardless of sex the most common diseases are anogenital (venereal) warts, while in Russia and Central Federal District -urogenitalny trichomoniasis. Significant prevalence of HPV infection, in view of oncological vigilance and frequent combination with inflammatory diseases of the genital organs, demonstrates the need for prevention of infection among the active population and the fast development of effective methods of early diagnosis and therapy.
DECREASE OF MIGRATION ACTIVITY AND PROLIFERATION OF BRO MELANOMA CELLS BY MIR-4286 INHIBITION
Authors: Tsyrenzhapova S. V , Sergeeva E. Yu , Aksenenko M. B , Palkina N. V , Komina A. V , Ruksha Tatiana G.
Published: September 2020

Mir-4286 takes part in the control of many oncogenes expression. One of signaling pathways regulated by mir-4286 is N-Glycan biosynthesis, hsa00510. Transfection of miR-4286 inhibitor in melanoma BRO cells leads to decreased activity of melanoma BRO cells migration and G2/M cell cycle arrest. These effects are supposed to be the result of the influence on N-Glycan biosynthesis. Therefore, mir-4286 inhibition can be the basis of new effective methods of melanoma treatment.
REDERMALIZATION OF THE SKIN AS A PATHOGENETICALLY VALID METHOD IN THE PERIOD OF CONVALESCENCE OF DERMATOSES
Authors: Romashkina Anastasia S. , Snarskaya E. S , Tkachenko S. B , Allenova A. S
Published: September 2020

The skin repair process with the method of redermalization after atopic dermatitis complicated by streptodermia is described. The analysis of domestic and foreign literature on the validity of redermalization use in the programs of patients recovery after the transferred dermatoses is given. The main mechanisms of appearance of pathological skin changes during the reconvalescence of atopic dermatitis are described and pathogenetic substantiation of the possibility of their correction with the help of redermalization is given. Control of skin changes at the structural level was carried out with confocal scanning laser microscopy (KSLM) to evaluate the efficacy of atopic dermatitis therapy during the reconvalescence with redermalization method.
THE CONDITION OF THE PSYCHOEMOTIONAL STATUS IN PATIENTS WITH DIFFUSE TELOGEN HAIR LOSS
Authors: Uryupina Elena L. , Malishevskaya N. P
Published: September 2020

Diffuse telogenetic alopecia is a polyethological disease accompanied by a disruption in the operation of the hair follicles cells and leading, in the future, to the growth cycle failure and development of the hair, which subsequently leads to thinning and excessive hair loss. The results of the study of psychoemotional disorders in patients with telogen hair loss identified by integrated analysis of anamnestic data, patient’s complaints, the survey using validated psychotherapeutic tests and subsequent consultation with a doctor-psychotherapist are presented. The relationship between personality type, psychological state and the severity of clinical manifestations was detected. The dominant triggering factors of development of diffuse alopecia severe forms were determined. The relationship between the severity of clinical manifestations and the position was found. Based on the analysis of the obtained data, literature review and the example of two clinical cases of patients with diffuse telogenous alopecia was shown the importance of identifying correction of alexithymia and depression with the aim of increasing the effectiveness of therapy.
ULTRASTRUCTURAL FEATURES OF THE MAIN CLINICAL VARIANTS OF BASAL CELL CARCINOMA, AS A FACTOR DETERMINING THE BIOLOGICAL BEHAVIOR OF THE TUMOR
Authors: Snarskaya Elena S. , Abdula Ibrahim
Published: September 2020

Histological variants of basal cell carcinoma (BСС) are characterized by a variety of structures depending on the location of the original tumor cells, their differentiation, the reaction of the surrounding tissue, the age of the patient, which causes a large number of histological classifications of the tumor. To evaluate the prognosis of the effectiveness of different treatment methods and the biological behavior of the ВCC, the clinical form and the corresponding histomorphological type of tumor are of great importance. Most of the primary foci of the ВCC are surface and micronodular (syn.: nodular) forms, rarely there is a scleroderm-like variant and extremely rarely fibroepithelioma of Pincus. Surface and micronodular forms of ВCC corresponding to the T1N0M0 characteristic (up to 2 cm in diameter) with a simple histological type of structure (multicentric, solidly compact) are regarded as tumors with a low risk of recurrence and progression. Materials and methods. Studying the features of the pathomorphological characteristics of the tumor and the frequency of various variants on the basis of an analysis of 223 ВCC biopsy specimens, we found that most often (54.7%) there was a solid type of tumor, less often -- superficial (12.7%), morphea (4.9% ), adenoid (10.9%), as well as ВCC with a piloidal (3.1%) and sebaceous (4.4%) differentiation. Among the biopsies analyzed in 6.8% of cases metatypic cancer was found. Conclusions: The histological structure of the tumor can determine its biological behavior and have prognostic significance. Thus, pronounced primitive angiogenesis, infiltrating growth and active stroma formation testify to tumor aggressiveness and clinically most correspond to the recurring macronodular and infiltrative clinical forms of BCC. The tumor is most aggressive in its basosquamous transformation, manifested in the emergence of two components of the tumor complex in the area of dyskeratosis and pseudoepitheliomatous hyperplasia of the epidermis: basal cell carcinoma and highly differentiated cancer, which corresponds to the formation of metatype skin cancer.
SUPERNUMERARY NIPPLE OR PAPPILOMA?
Authors: Saribekyan Erik K. , Zubovskaya A. G , Shirokikh I. M , Sidorenko V. S , Petrov A. N
Published: September 2020

Supernumerary nipples can be found in approximately 1 % of women. During the second and the third months of embryonic development when the regression of ectodermal thickening of mammary line takes place, incomplete regression with remaining of some foci may occur. These foci can further develop into a supernumerary breast or a supernumerary nipple. In this article, we would like to present five cases of supernumerary nipples. In 80% of cases, there was a single unilateral supernumerary nipple located along the right mammary line. In all the described cases this minor defect was efficiently excised for cosmetic purposes.
MICROELEMENTAL COMPOSITION OF HAIR IN DIFFUSE TELOGENOUS ALOPECIA
Authors: Uryupina E. L , Malishevskaya N. P
Published: September 2020

Adverse environmental conditions may affect the condition of the hair follicle, which require the optimal amount and ratio of minerals. The description of the diagnosis and treatment of microelements in patients suffering from diffuse telogen alopecia is presented. Based on the analysis of data from the literature review and the results of treatment of groups of patients the importance of identifying microelement imbalance in order to apply effective treatments is shown. The results obtained, showing the imbalance of macro - and micronutrients, including essential, are the basis for recommendations for patients with diffuse alopecia additional examination for definition of microelement composition of hair. This allows to prescribe different composition of microelement complexes that ensure the replenishment of certain microelements deficiency. And this provides an opportunity to reasonably resolve the issue of the need to include in the treatment plan detoxification measures to reduce the content of toxic and conditionally toxic microelements in the body.
VARIATIONS OF MICROBIOCENOSIS AND ACID-BASE BALANCE OF THE SKIN WITH ACNE VULGARIS AND THE POSSIBILITY OF THEIR CORRECTION WITH EUBIOTIC COMPLEX
Authors: Snarskaya Elena S. , Shnahova L. M , Shperling D. A
Published: September 2020

Presents a modern concept of the pathogenesis of acne vulgaris, data on the role of microbial factors and dysbiotic disorders in the development of endogenous intoxication. Endogenous intoxication syndrome (EIS) has a damaging effect on tissues, forming a complex of metabolic disorders that lead not only to suppression of the immune system organs functions, but also to interaction impairments of its individual effector links, causing the tendency of the macroorganism to nonspecific types of inflammation. The use of eubiotic complex “Eubikor” in the complex therapy of acne vulgaris leads to the normalization of the microbiocenosis of skin and parameters of the acid-base balance. The paper also provides its own successful clinical experience of using eubiotic complex “Eubikor” in the treatment of patients with acne vulgaris.
The application of transcranial magnetic stimulation for the treatment of metabolic syndrome
Authors: Frolkov Valeriy K. , Kulish A. V , Gerasimenko M. Yu , Nagornev S. N , Lavrent'eva O. V , Gusakova E. V , Rygina K. V
Published: September 2020

This article is focused n the analysis of the influence of transcranial magnetic stimulation on the hormonal regulation of carbohydrate and lipid metabolism in the patients presenting with metabolic syndrome. It is shown that the transcranial application of a magnetic field stimulates sensitivity of the tissues to insulin and thereby facilitates the reduction of arterial pressure and optimization of lipid and glucose metabolism.
The pathogenetic substantiation for the application of systemic magnetic therapy in the treatment of the patients presenting with chronic prostatitis and erectile dysfunction
Authors: Tereshin A. T , Bakurov E. E , Dolaev R. K , Dmitrenko G. D , Efimenko Aleksandr Pavlovich
Published: September 2020

Currently, therapeutic interventions for erectile dysfunction in chronic prostatitis encounter a number of obstacles due to the lack of system-structural approach to sex pathological syndromes so new possibilities of correction of sexual disorders should be explored adequately influencing all the hierarchical levels to ensure the copulatory cycle. The aim of the study is a pathogenetic substantiation of the system magnetic therapy in treatment of patients with chronic prostatitis with erectile dysfunction. Materials and methods. Monitoring of 40 patients with chronic prostatitis with erectile dysfunction aged 22 to 45 years was carried out. All patients taking physical therapy, prostate massage, psychotherapy correction of sexual maladjustment had a course of system magnetic therapy on Magnitoturbotron «EOL» in the «Standard» mode, the rotational speed of the magnetic field of 100 Hz in 1 Hz steps, the direction of rotation of the magnetic field was direct, clockwise, the maximum value of the magnetic field - 1.5-2.0 mT for 15 minutes a day in an amount of 15 procedures. Results. Application of the system of magnetic therapy for chronic prostatitis with erectile dysfunction has a direct effect on the prostate, helping to reduce edema, leukocyte infiltration and glands venules thrombosis and has antiplatelet activity, improving peripheral blood circulation and lymph flow, on the other hand, it increases the duration of erections, improves psychophysical and emotional state. The result is a normalization of the frequency of regular coitus, with the final phase of ejaculation, an improvement of mental and physical and emotional health, which is fundamental in terms of pathogenetic therapy of CP with erectile dysfunction. In addition surveys’ matrix correlation analysis carried out on a scale IIEF showed a clear relationship of the life quality improvement and the disappearance or significant decrease in the severity of pain, increased duration of erection and improvement of the functional status of the prostate.
Terrenkurs and physical training by walking
Authors: Badalov N. G , Barashkov G. N , Persiyanova-Dubova Anna Leonidovna
Published: September 2020

The present review article was designed to discuss the problems associated with the use of terrenkur training for the achievement of therapeutic and prophylactic effects and beneficial results of regular physical load in the form of walking, with special reference to the methods for the choice of walking intensity, calculation of the training pulse rate, the rules for the use of terrenkur, and its specific peculiarities in certain patients presenting with the cardiovascular and pulmonary diseases.
THE ANALYSIS AND PLANNING OF THE REHABILITATION EFFECTIVENESS IN THE PATIENTS PRESENTING WITH RHEUMATOID ARTHRITIS BASED ON THE APPLICATION OF THE INTERNATIONAL CLASSIFICATION OF FUNCTIONING, DISABILITY AND HEALTH CORE SET
Authors: Shoshmin A. V , Cherkashina I. V , Ponomarenko Gennady N. , Kovlen D. V , Besstrashnova Ya. K
Published: September 2020

The objective of the present study was the analysis of the comprehensive rehabilitation programs for the patients suffering from rheumatoid arthritis (RA). They were based on the International Classification of Functioning, Disability and Health (ICF) core set. The authors have undertaken the evaluation of the effectiveness of rehabilitation for two groups of patients with rheumatoid arthritis who had received the treatment based at different medical facilities (clinical hospitals, spa and health resorts). It was demonstrated that the use of the ICF core set for rheumatoid arthritis proved helpful for the development of a comprehensive rehabilitation program, the optimal distribution of responsibilities between the professionals, and the correct evaluation of the effectiveness of the programs. The implementation of the rehabilitation program based on the ICF core set resulted in a more effective sequence of the rehabilitation measures. The comprehensive rehabilitation program elaborated based the core set of the International Classification of Functioning, Disability and Health possesses ensured a highly efficient rehabilitation that permits to consider it as a practical rehabilitation technology that can be recommended for a wide clinical application.
THE INFLUENCE OF OZONE THERAPY ON THE MORPHOLOGIC CHANGES IN THE PATIENTS PRESENTING WITH PURULENT INFLAMMATION OF THE LUNGS IN THE EXPERIMENT
Authors: Sadykova Gulora A. , Rakhmatullaev Kh. U , Mavlyan-Khodjaev R. Sh , Zalyalova Z. S , Tadjikhodjaeva Yu. Kh
Published: September 2020

We have created the experimental model of chronic inflammation of lungs by means of prolonged mechanical irritation of the bronchi in 30 outbred rats and studied the morphological changes in the lung tissue of these animals rats in three series of experiments. Each rat was given an intraperitoneal injection of an ozonised saline solution produced by a «Binafsha» ozonator. The objective of the study was to compare a control group of healthy animals and the group of experimental animals with chronic purulent pneumonia. The prolonged irritation of the respiratory tract in experimental animals was found to induce the structural changes in the tissues of the lungs characteristic of chronic purulent inflammation. The course of treatment with the ozonised saline solution in healthy animals with experimentally modelled chronic purulent inflammation of the lungs did not have a negative impact on the general condition and the behaviour of the animals. The treatment of experimental chronic inflammation of lungs caused by prolonged mechanical irritation of the respiratory tract resulted in the improvement of the morphological status of the laboratory animals, but the purulent inflammation process failed to be completely resolved after the treatment which needs to be taken into consideration in the clinical practice.
THE EFFECTIVENESS OF THE METHODS FOR COMBINED HYDROREHABILITATION WITH A VIEW TO DEVELOPING SELECTED LOCOMOTOR FUNCTIONS IN THE PATIENTS PRESENTING WITH INFANTILE CEREBRAL PARALYSIS
Authors: Zyukov Ilya Mikhailovich
Published: September 2020

This article deals with the problem of physical rehabilitation of the children suffering from infantile cerebral paralysis. It is shown that the process of walking correction in such patients should be focused on the development of the ability to relax skeletal and respiratory muscles and the formation of the novel physical sensations, concurrence and coordination of movements. The author has elaborated the program for the rehabilitative treatment of the children suffering from infantile cerebral paralysis including therapeutic physical exercises and hydrokinesitherapy. The program is designed to promote the enhancement of the muscular strength, the formation of the new locomotor stereotype, and the development of the walking skills.
USING OF THE INTERNATIONAL CLASSIFICATION OF FUNCTIONING, DISABILITY AND HEALTH IN REHABILITATION PRACTICE IN MODEL OF PATIENTS WITH TRAUMATIC SPINAL CORD INJURY
Authors: Vasil’chenko Elena Mikhailovna , Lyakhovetskaya V. V , Karapetyan K. K , Filatov E. V , Zoloyev G. K
Published: September 2020

Implementation of the International Classification of Functioning, Disability and Health (ICF) tools in rehabilitation practice is a crucial task at the present-day stage. On the example of patients (n = 81) with traumatic spinal cord disease in the residual period, the methodology of the use of the ICF tools (basic set, categorical profile, table of interventions) in clinical practice was worked out: was defined the instruments for measuring the severity of functioning, activity and participation, algorithm of interaction of specialists was formed. This paper reflects the importance and methodology of appliance of the ICF tools in rehabilitation practice in terms of patients with traumatic spinal cord disease.
COMPARISON OF EFFICIENCY OF USE OF EXTERNAL COUNTERPULSATION AND PASSIVE NORMOBARIC HYPOXYTHERAPY IN FEMALE BASKETBALL PLAYERS 10-14 YEARS OLD
Authors: Lugovskaya Olga N. , Smolensky A. V , Zolicheva S. Yu
Published: September 2020

The aim of the study was to evaluate the effectiveness of the isolated and combined course application of normobaric hypoxia and enhanced external counterpulsation in young female basketball players. We examined 86 female basketball players aged 10-14 years who are in the sports specialization stage. Physiotherapeutic procedures (enhanced external counterpulsation and normobaric hypoxic therapy in climatic chamber conditions) were conducted in isolation and in combination in breaks between training sessions. Efficacy was assessed on the basis of changes in indicators before and after the course application of the procedures (PWC sample 170, maximum oxygen consumption, stress tests). The greatest increase in general and special working capacity was found in young female basketball players with a 10-day combined course of normobaric hypoxic therapy and external counterpulsation.
COMPREHENSIVE REHABILITATION OF PATIENTS WITH POST-CASTRATION SYNDROME
Authors: Bulakh O. A , Filatova Elena Vladimirovna
Published: September 2020

The effect of complex rehabilitation in patients with post-stroke syndrome after complex treatment, including operative treatment, chemotherapy and radiation therapy, was studied. Electrosleep in combination with normobaric hypoxic therapy significantly improved the condition of patients and can be a method of choosing the tactics of treatment of patients of this profile. The effectiveness of the treatment was 91%. The method contributes to a more prolonged remission of the disease and gives grounds to talk about the need for repeated courses of therapy with a frequency of no more than 2 times a year.
ULTRAPHONOPHORESIS OF ENZYME DRUGS IN TREATMENT OF POSTACNE SCARS
Authors: Talybova A. P , Kruglova L. S , Stenko Anna Germanovna
Published: September 2020

The most effective medication for aesthetic correction of skin scars is ultraphonophoresis of enzyme preparations. Under our supervision there were 20 patients aged 17.2 ± 2.4 years with a symptomatic complex who received a course of ultraphonophoresis of hyaluronidase cream (15 procedures performed every other day). Efficacy was assessed taking into account clinical high-grade indices: Vancouver scale, POSAS, Dermatological Life Quality Index. Efficacy according to the Vancouver scale was 100% for pain, itching decreased by 75% after 2 months and completely stopped after 6 months, color of the scar improved by 50%, stiffness decreased by 67%, thickness of scar deformation decreased by 50%. Ultraphonophoresis of hyaluronidase cream is a highly effective method of correction of the scars of the symptom complex postacne, which also determines the improvement in the quality of life of this category of patients according to the dynamics of the dermatological quality of life index. This method can be recommended for use in clinical practice.
RADONOTHERAPY IN COMPLEX TREATMENT OF WOMEN WITH CHRONIC CYSTITIS
Authors: Neimark A. I , Koltakov Alexander Sergeevich , Kablova I. V
Published: September 2020

The results of observation of 60 patients aged 35-65 years who received radon therapy in a complex of chronic cystitis treatment are presented. The inclusion of gynecological radon irrigation in the complex resulted in a decrease in the number of urination per day and urgent urges, a decrease in the time of urination, the total time of urination, an increase in the volume of urination, the maximum and average rate of urination. Gynecological irrigation with radon water can be recommended as a component of complex therapy for chronic cystitis.
COMBINED APPLICATION OF MICRONEEDLE RF-THERAPY AND INJECTIONS BY PLATELET-RICH PLASMA ACTIVATED BY AUTOLOGICAL THROMBIN IN AESTHETIC MEDICINE
Authors: Alenichev Andrey Yurievich , Kruglova L. S , Fedorov S. M , Sharypova I. V , Ast N. A
Published: September 2020

A retrospective assessment of the effectiveness of the application of a combination of radio-frequency radiation (needle lifting) and injections of platelet-enriched autologous human plasma was made in the correction of involuntary changes in the skin of the face and neck of 57 patients aged 40-65 years with signs of chronic aging and photodamage of the skin. Dermatological status was assessed before and after the reparative correction of involuntary changes in the skin through morphostructural analysis of the skin using the method of ultrasonography, visual analog scales, photography, studying the quality of life, and assessing patients’ satisfaction with the used treatment. To objectify the results, they were compared according to age: in the group of patients up to 49 years old and over 49 years of age. As a result of the application of the combined treatment method, the degree of manifestation of clinical signs of skin aging (the qualitative characteristics of the skin and the degree of wrinkles) markedly decreased, which contributed to an improvement in the quality of life of this category of patients. More than 90% of patients regardless of age noted good/very good efficacy and comfort of the combined method. Combined method of correction of involuntary changes in the face and neck skin, based on a combination of cellular technology with platelet activation by autologous thrombin and effect on the skin by needle lifting is a highly effective method of correcting involuntary skin changes.
EFFICIENCY OF APPLICATION OF INTERFERENCY THERAPY IN COMPLEX WITH PYRIMIDINE NUCLEOTIDES IN PATIENTS WITH VERTEBROGENIC RADICULOPATHIES
Authors: Guseinova Sadagat Ganbarovna , Imamverdieva S. S , Mustafaeva E. E , Mamedova M. Yu , Yusifova K. N
Published: September 2020

Clinical-neurophysiological bases of the combined use of Nucleo CMF forte preparation and interference therapy in the complex treatment of patients with vertebrogenic radiculopathies were studied. The beneficial effect of this therapeutic complex on the clinical course of the disease, more pronounced analgesic effect and regression of clinical manifestations, as well as improvement of quality of life indicators were proved. It has been established that the therapeutic effect of the complex application of Nucleo CMF forte and interference therapy lies in the improvement in the afferent and efferent links of the neuromotor apparatus, as well as the functional state of the spinal alpha-motoneurons associated with the acceleration of the regenerative processes. Activation of regenerative processes can also be associated with the restoration of certain morphological elements of the nervous system under the action of Nucleo CMF forte, as well as the normalization of the synthesis of complex lipids involved in cellular metabolism and synthesis of substances for the structural restoration of peripheral nerves. Carrying out neurotropic pharmacotherapy in combination with physiotherapy helps optimize therapeutic tactics in patients with vertebrogenic radiculopathies and is aimed at improving the quality of treatment, reducing the using of number of non-steroidal anti-inflammatory drugs and the frequency of relapse of the disease, and improving the quality of life of patients.
NONPHARMACEUTICAL TREATMENT AND PREVENTION OF METEOPATHIES IN PATIENTS WITH ARTERIAL HYPERTENSION
Authors: Mukhina Anastasia Alexandrovna , Smirnova M. D , Badalov N. G , Borodulina I. V , Marfina T. V , Barinova I. V , Blankova Z. N , Ageeva N. V , Ageev F. T
Published: September 2020

Dry carbon dioxide baths have a positive effect on blood pressure, the number of blood platelets, blood rheological properties of weather-dependent patients with arterial hypertension. The obtained results justify the possibility of dry carbon dioxide baths applying for treatment and prevention of meteopathies at patients with arterial hypertension.
DRINKING MINERAL WATER IN RESTORATIVE TREATMENT OF PATIENTS WITH METABOLIC SYNDROME
Authors: Botvineva L. A , Kaysinova Agnessa Sardoevna , Fedorova T. E , Samsonova N. A , Vasin V. A
Published: September 2020

The aim of the study was to assess the effectiveness of the integrated spa therapy of the metabolic syndrome (MS) with the use of drinking mineral waters (MB) of different chemical composition and mineralization, taking into account the dynamics of hormonal parameters, carbohydrate, lipid metabolism, liver function. Eighty patients with MS received a standard clinical and laboratory examination at the beginning and at the end of the course of treatment. By random sampling, two groups of 40 people were formed, each of whom received an internal intake of MB Essentuki-Novaya or Essentuki No. 4. It was established that the complex spa treatment of patients with MS and the pathology of carbohydrate metabolism in the form of impaired fasting glucose and non-alcoholic fatty liver disease with drinking MB is pathogenetically directed and includes the main means of actively affecting the well-being of patients, body weight, metabolic processes, hormonal regulatory systems and liver function, the course of concomitant diseases. The results of the study allowed us to recommend MB Essentuki-Novaya for the specified category of people as a curative and preventive agent in order to prevent further progression of carbohydrate metabolism and pathological changes in the liver.
LASER TECHNOLOGIES IN THE CORRECTION OF NONNEOPLASTIC MELANIN HYPERPIGMENTATION OF THE SKIN
Authors: Ikonnikova Evgeniya Vladimirovna , Korchazhkina N. V , Stenko A. G
Published: September 2020

The article briefly describes the modern views on the main causes of nonneoplastic melanin hyperpigmentation of the skin and also consider various types of laser and light therapy and effective combination of some methods of treatment. Under observation were 30 patients with nonneoplastic hyperpigmentation of the skin on both sides of the face (solar lentigo, ephelides, melasma, posttraumatic hyperpigmentation), skin type I-III. Patients were treated with using a neodymium laser (1064 nm) with low fluence per half of the face and an alexandrite laser (755 nm) with low fluence to the other half of the face in the same procedure. A total of 4 procedures were performed with a weekly interval. Both variants of therapy were equally effective in the treatment of nonneoplastic melanin hyperpigmentation of the skin and showed a high safety profile.
PECULIARITIES OF COMPLEX IMPACT OF ELECTRONEUROMYOSTIMULATION AND ACUPUNCTION IN LUMB-CROSS DORSOPATHY
Authors: Omochev Omar Gadjievich , Chililov M. A
Published: September 2020

The article presents the results of the evaluation of the effect of complex application of low-frequency electrotherapy and acupuncture on the condition of the lumbosacral section in 42 patients with degenerative-dystrophic diseases of the spine. Under the influence of the developed complex, the condition of patients with lumbosacral dorsopathy and hemodynamics in the lower extremities improved steadily. The effect of the combined use of low-frequency electrotherapy and reflexotherapy on the clinical course of dorsopathy is more pronounced than in traditional medicamentous treatment. It is almost the same according to the criteria for the effectiveness of treatment, but it differs by the mechanism of influence on the body.