bluuebunny/crossref_metadata_2025 huggingface dataset:
α-Melanocyte-stimulating hormone alleviates pathological cardiac remodeling via melanocortin 5 receptor
Authors: Suominen Anni , Saldo Rubio Guillem , Ruohonen Saku , Szabó Zoltán , Pohjolainen Lotta , Ghimire Bishwa , Ruohonen Suvi T , Saukkonen Karla , Ijas Jani , Skarp Sini , Kaikkonen Leena , Cai Minying , Wardlaw Sharon L , Ruskoaho Heikki , Talman Virpi , Savontaus Eriika , Kerkelä Risto , Rinne Petteri
Published: March 2024

α-Melanocyte-stimulating hormone (α-MSH) regulates diverse physiological functions by activating melanocortin receptors (MC-R). However, the role of α-MSH and its possible target receptors in the heart remain completely unknown. Here we investigate whether α-MSH could be involved in pathological cardiac remodeling. We found that α-MSH was highly expressed in the mouse heart with reduced ventricular levels after transverse aortic constriction (TAC). Administration of a stable α-MSH analog protected mice against TAC-induced cardiac hypertrophy and systolic dysfunction. In vitro experiments revealed that MC5-R in cardiomyocytes mediates the anti-hypertrophic signaling of α-MSH. Silencing of MC5-R in cardiomyocytes induced hypertrophy and fibrosis markers in vitro and aggravated TAC-induced cardiac hypertrophy and fibrosis in vivo. Conversely, pharmacological activation of MC5-R improved systolic function and reduced cardiac fibrosis in TAC-operated mice. In conclusion, α-MSH is expressed in the heart and protects against pathological cardiac remodeling by activating MC5-R in cardiomyocytes. These results suggest that analogs of naturally occurring α-MSH, that have been recently approved for clinical use and have agonistic activity at MC5-R, may be of benefit in treating heart failure.
Rapid measurement of hemoglobin-oxygen dissociation by leveraging Bohr effect and Soret band bathochromic shift
Authors: Sekyonda Zoe , An Ran , Goreke Utku , Man Yuncheng , Monchamp Karamoja , Bode Allison , Zhang Qiaochu , El-Gammal Yasmin , Kityo Cissy , Kalfa Theodosia A. , Akkus Ozan , Gurkan Umut A.
Published: March 2024

We present a rapid hemoglobin-oxygen dissociation measurement approach to screen for and detect hemoglobin-oxygen affinity abnormalities and to evaluate the function and efficacy of hemoglobin modifying therapies within minutes.
Structure, stability, reactivity and bonding in noble gas compounds
Authors: Pal Ranita , Chattaraj Pratim Kumar
Published: March 2024

Most commonly acknowledged as the least reactive element group in the periodic table, noble gases can form complexes under nearly ambient conditions. This Perspective spans their theoretical prediction and bonding categories.
Self-indicating polymers: a pathway to intelligent materials
Authors: Bayat Mobina , Mardani Hanieh , Roghani-Mamaqani Hossein , Hoogenboom Richard
Published: March 2024

Self-indicating polymers undergo detectable variations in response to stimuli. Important mechanisms of self-indication are aggregation, phase transition, covalent and non-covalent bond cleavage, isomerization, charge transfer, and energy transfer.
Mitochondria-targeted BODIPY dyes for small molecule recognition, bio-imaging and photodynamic therapy
Authors: Wang Sisi , Gai Lizhi , Chen Yuncong , Ji Xiaobo , Lu Hua , Guo Zijian
Published: March 2024

This review focuses on the design strategy, spectroscopic characteristics, and functionalization of mitochondrion-targeted BODIPY dyes, providing an overview of these dyes for mitochondrion-targeted bioimaging and photodynamic therapy.
Peptide hydrogen-bonded organic frameworks
Authors: Vijayakanth Thangavel , Dasgupta Sneha , Ganatra Pragati , Rencus-Lazar Sigal , Desai Aamod V. , Nandi Shyamapada , Jain Rahul , Bera Santu , Nguyen Andy I. , Gazit Ehud , Misra Rajkumar
Published: March 2024

This tutorial review discusses the design principles, implications, and future challenges associated with peptide-based hydrogen-bonded porous frameworks (P-HPFs).
High-sensitivity analysis of trace elements in water using femtosecond LIBS with dry droplet pretreatment on a metallic substrate
Authors: Chen Yutong , Wan Xiangtong , Si Jiarui , Han Jianhui , Chen Anmin , Jin Mingxing
Published: March 2024

Femtosecond LIBS with dry droplet pretreatment for detecting trace elements in water showed a significant decrease in LOD with increasing titration number, indicating that this method can achieve high sensitivity analysis of trace elements in water.
An ultrasensitive label-free RNase H assay based on in vitro transcription of fluorogenic light-up aptamer
Authors: Lee Jinhwan , Kim Hansol , Li Yan , Lee Seoyoung , Park Hyun Gyu
Published: March 2024

A new ultrasensitive method to identify RNase H activity was developed by utilizing in vitro transcription of fluorogenic light-up aptamers. We successfully determined RNase H activity with the lowest reported limit of detection of 0.000156 U mL−1.
Universal nanocomposite coating with antifouling and redox capabilities for electrochemical affinity biosensing in complex biological fluids
Authors: Bharti Aditya Manu , Rakesh Kumar R. K. , Chuang Cheng-Hsin , Shaikh Muhammad Omar
Published: March 2024

Multifunctional nanocomposite coating for electrochemical affinity biosensing in complex biological fluids.
Unraveling the origins of the coexisting localized-interfacial mechanism in oxide-based memristors in CMOS-integrated synaptic device implementations
Authors: Koh Eng Kang , Dananjaya Putu Andhita , Poh Han Yin , Liu Lingli , Lee Calvin Xiu Xian , Thong Jia Rui , You Young Seon , Lew Wen Siang
Published: March 2024

This work introduces a scalable CMOS-integrated memristive device designed to demonstrate dual-mode functionality encompassing both localized (digital) and interfacial (analog) switching mechanisms.
A FAPI-conjugated FITC fluorescence probe for targeted cancer imaging
Authors: Wu Dan , Zhou Xuesu , Zhang Jiaqi , Xue Fengfeng , Ding Lexuan , An Lu , Tian Qiwei
Published: March 2024

The targeted fluorescent probe, FITC-FAPI, can achieve high accumulation at the tumor site and extend the residence time of the fluorescent probe, resulting in clear tumor imaging.
Straightforward α-allylation of carbonyl compounds with alkenes via α-carbonyl radical intermediates
Authors: Liu Sien , Liao Yanjing , Li Hongyi , Xu Biping , Zhang Xiaofeng , Shang Yaping , Su Weiping
Published: March 2024

We report that the direct oxidative cross-coupling of carbonyl compounds with simple alkenes is realized to synthesize α-allylated carbonyl compounds by identifying the bisphosphine ligand BINAP that enables the copper catalyst to integrate two different catalytic cycles in a one-pot system.
Spectraformer: deep learning model for grain spectral qualitative analysis based on transformer structure
Authors: Chen Zhuo , Zhou Rigui , Ren Pengju
Published: March 2024

This study used portable near-infrared spectroscopy and various preprocessing techniques to explore universal methods. The spectraformer model showed superior performance among the compared machine learning models.
Sub-mm3 dimensional scaling of fully-integrated additively-fabricated microsupercapacitors for embedded energy storage applications
Authors: Hodaei Amin , Subramanian Vivek
Published: March 2024

Microsupercapacitors (MSCs) are attractive energy devices for applications in IoT, wireless sensors, and other microelectronic systems due to their small footprints.
Impact of Ni(ii) coordinatively unsaturated sites and coordinated water molecules on SO2 adsorption by a MOF with octanuclear metal clusters
Authors: Obeso Juan L. , Gopalsamy Karuppasamy , Wahiduzzaman Mohammad , Martínez-Ahumada Eva , Fan Dong , Lara-García Hugo A. , Carmona Francisco J. , Maurin Guillaume , Ibarra Ilich A. , Navarro Jorge A. R.
Published: March 2024

The influence of Ni(ii) coordinatively unsaturated metal sites and coordinated water on the SO2 adsorption performance of NiBDP were investigated.
Dopant clustering and vacancy ordering in neodymium doped ceria
Authors: Ming Jing , Leszczyńska-Redek Marzena , Malys Marcin , Wrobel Wojciech , Jamroz Jan , Struzik Michal , Hull Stephen , Krok Franciszek , Abrahams Isaac
Published: March 2024

Reverse Monte Carlo analysis of total neutron scattering data on neodymium doped ceria reveals details of local structure including dopant–oxide ion vacancy association, dopant clustering and oxide ion vacancy pair ordering in the 〈100〉 direction.
Ultrafast synthesis of cation/anion co-doped Li-rich layered oxide cathodes with Li+/Ni2+ mixing structural defects
Authors: Zhu Wei , Zhao Jiwei , Yang Ming , Zhan Jialu , Su Hai , Zeng Cuihua , Li Zhenfei , Zhang Jing , Chen Yanan , Xu Yunhua
Published: March 2024

An ultrafast nickel foil-based thermal shock method is reported to synthesize cation/anion co-doped Li-rich layered oxide with Li+/Ni2+ mixing in seconds.
Mechanism of lithium dendrite growth on iron surfaces toward high-performance and safe anode-free lithium metal batteries
Authors: Liu Songchang , Li Nannan , Tang Yingqi , Mukamel Shaul , Lee Jin Yong
Published: March 2024

Selecting the Fe(111) surface, reducing surface cracks, and controlling the surface nanogroove structures can effectively prevent the formation of irreversible Li dendrites on the Fe collector, resulting in better performance of anode-free LMBs.
Correction: Ultra-broadband microwave absorption of (Mn0.2Fe0.2Zn1.2)x substituted Co2Y hexaferrites with a self-aligned sheet stacked, highly c-axis oriented and multi-domain structure
Authors: Liu Yijian , Li Haifeng , Yan Xutao , Sun Jihui , Zang Jiabao , Luo Xiang , Sun Li , Zhang Meijie
Published: March 2024

Correction for ‘Ultra-broadband microwave absorption of (Mn0.2Fe0.2Zn1.2)x substituted Co2Y hexaferrites with a self-aligned sheet stacked, highly c-axis oriented and multi-domain structure’ by Yijian Liu et al., J. Mater. Chem. A, 2023, https://doi.org/10.1039/d3ta05473j.
Multifunctional nanocomposites mediated novel hydrogel for diabetic wound repair
Authors: Zhou Yingjuan , Yang Jiaxin , Li Yan , Shu Xin , Cai Yucen , Xu Ping , Huang Wenyan , Yang Zhangyou , Li Rong
Published: March 2024

Synthesis strategy of glucose-responsive intelligent hydrogels based on multifunctional nanocomposite nodes and their mechanism in diabetic and infected diabetic wounds.
Metabolic labeling-mediated visualization, capture, and inactivation of Gram-positive bacteria via biotin–streptavidin interactions
Authors: Zheng Yongfang , Jiang Mingyi , Zhu Xinyu , Chen Yuyuan , Feng Lisha , Zhu Hu
Published: March 2024

A metabolically-driven probe targets Gram-positive bacteria, offering imaging and inactivation via streptavidin-modified reagents, showcasing innovative metabolic incorporation.
Two multifunctional Dy(iii)-based metal–organic frameworks exhibiting proton conduction, magnetic properties and second-harmonic generation
Authors: Liao Ya-Qing , Xiong Tian-Zheng , Xie Kang-Le , Zhang Huan , Hu Jun-Jie , Wen He-Rui
Published: March 2024

Two novelty Dy-MOFs were synthesized using H4DTTP-2OMe ligand. MOF 1 displays a more superior proton conductivity, field-induced single molecule magnets behavior and obvious second-order nonlinear optical properties.
Ultrafast spectroscopy of the hydrophilic carotenoid crocin at various pH
Authors: Özcan Emrah , Šímová Ivana , Bína David , Litvín Radek , Polívka Tomáš
Published: March 2024

Exploring effect of pH on excited state dynamics of the hydrophilic carotenoid crocin demonstrates pH-dependent alterations of crocin photophysics, suggesting structural modifications caused by pH change.
Zinc adeninate metal–organic framework-coated optical fibers for enhanced luminescence-based detection of rare earth elements
Authors: Crawford Scott E. , Burgess Ward A. , Kim Ki-Joong , Baltrus John P. , Diemler Nathan A.
Published: March 2024

Luminescence-based detection of economically critical rare earth elements is enhanced by immobilizing a metal–organic framework sensitization material onto an optical fiber, facilitating sensor regeneration and solvent removal for better signal.
A simple 230 MHz photodetector based on exfoliated WSe2 multilayers
Authors: Strauß Fabian , Kohlschreiber Pia , Keck Jakob , Michel Patrick , Hiller Jonas , Meixner Alfred J. , Scheele Marcus
Published: March 2024

We demonstrate 230 MHz photodetection and a switching energy of merely 27 fJ using WSe2 multilayers and a very simple device architecture.
Brain-inspired computing: can 2D materials bridge the gap between biological and artificial neural networks?
Authors: Singh Deependra Kumar , Gupta Govind
Published: March 2024

The development of excellent non-volatile storage and computing devices based on two-dimensional layered materials is necessary for overcoming the memory bottleneck of the traditional von-Neumann structure-based devices.
Fine tuning of pore size in metal–organic frameworks for superior removal of U(vi) from aqueous solution
Authors: Fu Tianyu , Liu Hongjuan , Wang Xinyi , Liu Yingjiu
Published: March 2024

The pore structure of metal–organic frameworks (MOFs) is crucial to their adsorption performance, and it is still a challenge to precisely control the pore size to realize superior removal of uranium.
Recent advances in the total synthesis of galantamine, a natural medicine for Alzheimer's disease
Authors: Cheng Bichu , Wang Qi , An Yi , Chen Fener
Published: March 2024

This review discusses the recent synthetic strategies for the total synthesis of galantamine, a natural medicine for the treatment of Alzheimer's disease, focusing on the construction of the key quaternary center and the asymmetric synthesis.
Investigating the efficacy of green solvents and solvent-free conditions in hydrogen-bonding mediated organocatalyzed model reactions
Authors: Chetty Lloyd C. , Kruger Hendrik G. , Arvidsson Per I. , Naicker Tricia , Govender Thavendran
Published: March 2024

The efficacy of green solvents and neat conditions in organocatalysed reactions were investigated. The results suggest cyclopentyl methyl ether and neat conditions could serve as alternatives, potentially enhancing the processes' sustainability.
Effects of salinity on the flow of dense colloidal suspensions
Authors: Lagoin Marc , Piednoir Agnès , Fulcrand Rémy , Bérut Antoine
Published: March 2024

We studied how the flowing dynamics of dense suspensions of silica micro-particles in microfluidic rotating drums experiments is modified when the inter-particles repulsion is progressively screened by increasing the ionic force of the suspension.
High wide-temperature-range thermoelectric performance in n-PbSe integrated with quantum dots
Authors: Xia Qinxuan , Zhang Qingtang , Gong Yaru , Huang Xinqi , Iqbal Muhammad Faisal , Xiang Deshang , Liu Yuqi , Li Song , Ying Pan , Tang Guodong
Published: March 2024

An extraordinary average ZT of ∼1 as well as a high peak ZT of 1.44 is realized in n-PbSe integrated with quantum dots.
A DFT study of the mechanism of NH3-SCR NOx reduction over Mn-doped and Mn–Ti co-doped CoAl2O4 catalysts
Authors: Wang Xu , Wang Weiyao , Xiong Wei , Jiang Xiaodi , Ouyang Taoyuan , Bai Yaoning , Cai Xiaoming , Cai Jinming , Tan Honglin
Published: March 2024

This study reveals that manganese-doped and manganese-titanium co-doped catalysts enhance the catalytic performance of cobalt-chromium spinel NH3-SCR, leading to improved air quality and reduced emissions.
Ionic liquid-regulated PbI2 layers and defect passivation for efficient perovskite solar cells
Authors: Sun Yonggui , Hu Ruiyuan , Wang Fei , Wang Taomiao , Liang Xiao , Zhou Xianfang , Yang Guo , Li Yongjun , Zhang Fan , Zhu Quanyao , Li Xing’ao , Hu Hanlin
Published: March 2024

In this work, formamidine acetate (FAAc) was introduced in the two-step method to regulate perovskite crystallization and passivate defects, which resulted in achieving the PCE of device exceeding 24% with notable improvements in stability.
Protective roles of peroxiporins AQP0 and AQP11 in human astrocyte and neuronal cell lines in response to oxidative and inflammatory stressors
Authors: Amro Zein , Collins-Praino Lyndsey E. , Yool Andrea J.
Published: March 2024

In addition to aquaporin (AQP) classes AQP1, AQP4 and AQP9 known to be expressed in mammalian brain, our recent transcriptomic analyses identified AQP0 and AQP11 in human cortex and hippocampus at levels correlated with age and Alzheimer’s disease (AD) status; however, protein localization remained unknown. Roles of AQP0 and AQP11 in transporting hydrogen peroxide (H2O2) in lens and kidney prompted our hypothesis that up-regulation in brain might similarly be protective. Established cell lines for astroglia (1321N1) and neurons (SHSY5Y, differentiated with retinoic acid) were used to monitor changes in transcript levels for human AQPs (AQP0 to AQP12) in response to inflammation (simulated with 10–100 ng/ml lipopolysaccharide [LPS], 24 h), and hypoxia (5 min N2, followed by 0 to 24 h normoxia). AQP transcripts up-regulated in both 1321N1 and SHSY5Y included AQP0, AQP1 and AQP11. Immunocytochemistry in 1321N1 cells confirmed protein expression for AQP0 and AQP11 in plasma membrane and endoplasmic reticulum; AQP11 increased 10-fold after LPS and AQP0 increased 0.3-fold. In SHSY5Y cells, AQP0 expression increased 0.2-fold after 24 h LPS; AQP11 showed no appreciable change. Proposed peroxiporin roles were tested using melondialdehyde (MDA) assays to quantify lipid peroxidation levels after brief H2O2. Boosting peroxiporin expression by LPS pretreatment lowered subsequent H2O2-induced MDA responses (∼50%) compared with controls; conversely small interfering RNA knockdown of AQP0 in 1321N1 increased lipid peroxidation (∼17%) after H2O2, with a similar trend for AQP11 siRNA. Interventions that increase native brain peroxiporin activity are promising as new approaches to mitigate damage caused by aging and neurodegeneration.
Genome organization across scales: mechanistic insights from in vitro reconstitution studies
Authors: Oberbeckmann Elisa , Oudelaar A. Marieke
Published: March 2024

Eukaryotic genomes are compacted and organized into distinct three-dimensional (3D) structures, which range from small-scale nucleosome arrays to large-scale chromatin domains. These chromatin structures play an important role in the regulation of transcription and other nuclear processes. The molecular mechanisms that drive the formation of chromatin structures across scales and the relationship between chromatin structure and function remain incompletely understood. Because the processes involved are complex and interconnected, it is often challenging to dissect the underlying principles in the nuclear environment. Therefore, in vitro reconstitution systems provide a valuable approach to gain insight into the molecular mechanisms by which chromatin structures are formed and to determine the cause-consequence relationships between the processes involved. In this review, we give an overview of in vitro approaches that have been used to study chromatin structures across scales and how they have increased our understanding of the formation and function of these structures. We start by discussing in vitro studies that have given insight into the mechanisms of nucleosome positioning. Next, we discuss recent efforts to reconstitute larger-scale chromatin domains and loops and the resulting insights into the principles of genome organization. We conclude with an outlook on potential future applications of chromatin reconstitution systems and how they may contribute to answering open questions concerning chromatin architecture.
Type III intermediate filaments in redox interplay: key role of the conserved cysteine residue
Authors: Pajares María A. , Pérez-Sala Dolores
Published: March 2024

Intermediate filaments (IFs) are cytoskeletal elements involved in mechanotransduction and in the integration of cellular responses. They are versatile structures and their assembly and organization are finely tuned by posttranslational modifications. Among them, type III IFs, mainly vimentin, have been identified as targets of multiple oxidative and electrophilic modifications. A characteristic of most type III IF proteins is the presence in their sequence of a single, conserved cysteine residue (C328 in vimentin), that is a hot spot for these modifications and appears to play a key role in the ability of the filament network to respond to oxidative stress. Current structural models and experimental evidence indicate that this cysteine residue may occupy a strategic position in the filaments in such a way that perturbations at this site, due to chemical modification or mutation, impact filament assembly or organization in a structure-dependent manner. Cysteine-dependent regulation of vimentin can be modulated by interaction with divalent cations, such as zinc, and by pH. Importantly, vimentin remodeling induced by C328 modification may affect its interaction with cellular organelles, as well as the cross-talk between cytoskeletal networks, as seems to be the case for the reorganization of actin filaments in response to oxidants and electrophiles. In summary, the evidence herein reviewed delineates a complex interplay in which type III IFs emerge both as targets and modulators of redox signaling.
Privacy‐preserving data integration scheme in industrial robot system based on fog computing and edge computing
Authors: Han Song , Ma Hui , Taherkordi Amir , Lan Dapeng , Chen Yange
Published: March 2024

To solve the security problems of the moving robot system in the fog network of the Industrial Internet of Things (IIoT), this paper presents a privacy‐preserving data integration scheme in the moving robot system. First, a novel data collection enhancement algorithm is proposed to enhance the image effects, and a k‐anonymous location and data privacy protection protocol based on Ad hoc network (Ad hoc‐based KLDPP protocol) is designed in secure data collection phase to protect the privacy of location and network data. Second, the secure multiparty computation with verifiable key sharing is introduced to realize the valid computation against share cheating in the robot system. Third, the ciphertext classification method in a neural network is considered in the secure data storage process to realize the special application. Finally, experiments and simulations are conducted on the robot system of fog computing in the IIoT. The results demonstrate that the proposed scheme can improve the security and efficiency of the said robot system.
Data sonification of film capacitors
Authors: Zhang Yong‐Xin , Liu Di‐Fan , Wei Xin‐Yi , Wang Xin‐Jie , Chen Fang‐Yi , Feng Qi‐Kun , Cao Wen‐Yuan , Dong Wen‐Zhuo , Shah Faisal Mehmood , Liu Yu‐Xiao , Wu Zhi‐Yuan , Wang Jian‐Tao , Zhong Shao‐Long , Dang Zhi‐Min
Published: March 2024

Film capacitors are playing an increasingly important role in power‐related fields, driven by the continuous development of dielectric materials and practical needs. Long‐term accumulation has also led to an increasing wealth of data related to film capacitors. Sonification opens up a new way for people to make good use of data from film capacitors. A framework for sonifying film capacitors data based on TwoTone is presented. Based on the analysis and discussion, it is clear that the sonification results can easily represent the monotonic variation pattern of film capacitors data. What's more, the sonification results increase the possibility that people pay attention to the changing trend of film capacitors data when there is no significant difference in the visual perception of the data. In addition to providing a new way of music generation of electrical equipment, the method proposed is expected to contribute to theory reference in typical scenarios, such as factory calibration of film capacitors, monitoring of film capacitor operation status, and presentation of statistical data of film capacitors' dielectric materials, which will help us to better understand the distribution characteristics of polymer films.
Very high step‐down coupled inductor two‐phase buck converter with single magnetic element and inherent clamp voltage capability
Authors: Esfahani Ahmad Ghamsari , Adib Ehsan
Published: March 2024

This paper proposed a new two‐phase high step‐down DC–DC converter is proposed. This converter is derived from the two‐phase series‐capacitor converter. The proposed converter replaces the series capacitor with a new structure that integrates Valley‐Fill circuit and coupled‐inductors concepts. This replacement can improve the voltage gain of the converter as well as a considerable reduction of diodes voltage stress. The proposed structure implements a dual‐phase buck using a single magnetic element. Also, the proposed structure inherently limits the voltage spikes due to the leakage inductance of coupled inductors without any additional clamp circuit. The proposed converter is analyzed, and design guidelines are provided. A 300–24 V prototype converter is implemented to justify the validity of circuit operation and the theoretical analysis.
Dynamics of 2023 FW14, the second L4 Mars trojan, and a physical characterization using the 10.4 m Gran Telescopio Canarias
Authors: de la Fuente Marcos R. , de León J. , de la Fuente Marcos C. , Alarcon M. R. , Licandro J. , Serra-Ricart M. , Geier S. , Cabrera-Lavers A.
Published: March 2024

Context. Known Mars trojans could be primordial small bodies that have remained in their present-day orbits for the age of the Solar System. Their orbital distribution is strongly asymmetric; there are over a dozen objects at the L5 point and just one at L4, (121514) 1999 UJ7. Most L5 trojans appear to form a collision-induced asteroid cluster, known as the Eureka family. Asteroid 2023 FW14 was recently discovered and it has a robust orbit determination that may be consistent with a Mars trojan status.

Aims. Our aim is determine the nature and dynamical properties of 2023 FW14.

Methods. We carried out an observational study of 2023 FW14 to derive its spectral class using the OSIRIS camera spectrograph at the 10.4 m Gran Telescopio Canarias. We investigated its possible trojan resonance with Mars using direct N-body simulations.

Results. The reflectance spectrum of 2023 FW14 is not compatible with the olivine-rich composition of the Eureka family; it also does not resemble the composition of the Moon, although (101429) 1998 VF31 does. The Eureka family and 101429 are at the L5 point. The spectrum of 2023 FW14 is also different from two out of the three spectra in the literature of the other known L4 trojan, 121514, which are of C-type. The visible spectrum of 2023 FW14 is consistent with that of an X-type asteroid, as is the third spectrum of 121514. Our calculations confirm that 2023 FW14 is the second known L4 Mars trojan although it is unlikely to be primordial; it may remain in its present-day “tadpole” path for several million years before transferring to a Mars-crossing orbit. It might be a fragment of 121514, but a capture scenario seems more likely.

Conclusions. The discovery of 2023 FW14 suggests that regular Mars-crossing asteroids can be captured as temporary Mars trojans.
Advancements in renewable energy sources (solar and geothermal): A brief review
Authors: Rakhmatov Abdugani , Primov Odil , Mamadaliyev Maxammadjon , Tòrayev Shoyatbek , Xudoynazarov Utkir , Xaydarov Shoxboz , Ulugmurodov Elshod , Razzoqov Ilhom
Published: March 2024

This scientific article provides an in-depth review of recent advancements in renewable energy sources, examining their significance in addressing global energy challenges. The paper covers various types of renewable energy, including solar, wind, hydropower, geothermal, and biomass, emphasizing technological developments, efficiency improvements, and environmental considerations. Additionally, the article discusses the current state of renewable energy adoption globally and its potential impact on reducing carbon emissions. The analysis integrates findings from recent studies and research papers to present a comprehensive overview of the current landscape of renewable energy technologies.
Vegetable raw materials for the production of fibrous semi-finished products
Authors: Akmalaiuly Kezhebek , Tolegenova Aigerim
Published: March 2024

In the economic sphere, they envisage the creation of their own production facilities to produce fibrous semi–finished products - cellulose and its derivatives based on the wood of various hardwoods from the Central Asian region, whose plantations expand every year. Great attention should be paid to rice and wheat straw. Given that rice straw is not used as feed in animal husbandry and is simply burned, thus damaging the ecology of the country, we consider it necessary to carry out scientific work on the production of semi-finished modified fibrous products from local annual cellulose-containing plants. Waste generated by cutting poplar in the form of branches, sawdust, shavings, etc. can also serve as an additional source of raw wood materials to produce cellulose.
Keeping up with changing technologies: The nexus between architecture and engineering
Authors: Mba Emeka J. , Okeke Francis O. , Igwe Ajuluchukwu E. , Achara Chukwuemerie E. , Chimbuchi Okwaraejesu , Precious Obasi , Wilson Udeh
Published: March 2024

Advancements in technology are fundamentally transforming architectural and engineering domains within the building and construction sector. This study investigates the intersection of both fields in assimilating emerging innovations by eliciting empirical perspectives from practitioners. Embracing a quantitative approach, a survey was conducted among 203 architects and 392 engineers within Enugu metropolis, Nigeria using proportionate random sampling. Results were analyzed using descriptive statistics, revealing insights into awareness, perception, and collaboration concerning emerging technologies. Findings revealed high awareness but uneven adoption of building information modeling tools, with 97.3% of architects employing them versus only 25.4% of engineers. Although virtual reality and cloud-based platforms showed promise for enhancing project coordination, actual usage lagged significantly, likely owing to systemic and attitudinal barriers. However, respondents strongly endorsed tighter, technologically unified partnerships to smooth industry transformation, necessitating digital literacy interventions, supportive policy and binding protocols bridging persistent digital divides stalling seamless innovation diffusion along construction value chains.
Determination of total heat transfer resistance, temperature line and moisture formation of condensate of the external walls’ multilayer construction
Authors: Asatov Nurmuhamat , Alikabulov Shukhrat , Radjabov Yorkinbek , Ziyaviddinov Dilshod , Sagatov Bakhodir
Published: March 2024

To create a moderate climate in the premises of newly built low-rise residential buildings, this article presents theoretical calculations of the design of external walls made of small gas blocks, the cavities of which are filled with heavy concrete and thermal insulation material. As a result of theoretical calculations, the total resistance to heat transfer, thermal inertia, temperature in the layers of the wall, temperature line, humidity regime and heat absorption coefficient of the external wall structure, built from small gas blocks filled with heavy concrete and thermal insulation, were determined. material.
Model Equations of the Theory of Elasticity in Strains: Classical and New Formulations
Authors: Khaldjigitov Abduvali , Djumayozov Umidjon
Published: March 2024

The article is devoted to the construction of model equations of the theory of elasticity with respect to deformations. Classical and new versions of boundary value problems of the theory of elasticity in strains are considered. In the classical version, model equations in strains are constructed within the framework of the Beltrami-Michell equations. A new version of model equations in strains is based on a new formulation of boundary value problems of the theory of elasticity in stresses. Discrete equations are constructed using the finite-difference method for two-dimensional problems. The well-known problem of tension a rectangular plate with a parabolic load applied on opposite sides has been solved. By comparing the numerical results of boundary value problems in classical and new formulations, as well as the Timoshenko-Goodier solution, the validity of the formulated model equations in strains and the reliability of the obtained numerical results are ensured.
Adaptive Risk Management in Road Construction: Oyon-Ambo Highway Insights, El Niño 2019 Case Study
Authors: Ariza Flores Victor Andre , Salvador Rachel
Published: March 2024

This research provides an in-depth analysis of the challenges faced during the construction of the Oyon-Ambo highway in Peru, particularly during the extreme rainfall events associated with the 2019 El Niño phenomenon. Situated in the high Andean area of the Pasco region, this rigid pavement road project encountered significant disruptions due to the extraordinary weather conditions. The adjacent Chaupihuaranga River experienced increased flow rates, causing extensive damage to the road and necessitating substantial modifications to the engineering plans. Focusing on 14 critical sectors identified in the project's technical file as prone to instability, the study details the accelerated degradation and eventual destruction of these sectors due to the intense rainfall. Emphasizing the importance of adaptive risk management in road construction, especially in regions susceptible to natural phenomena like El Niño, the paper underscores the need for responsive reengineering approaches based on specific damage types. It also highlights the critical role of continuous monitoring and evaluation in adapting to environmental changes. The insights from the Oyon-Ambo highway case offer valuable lessons for future road construction projects, underscoring the importance of proactive and adaptive risk management strategies to minimize the impacts of extraordinary natural events.
Effect of Obliquely Directed Brick TNT Explosive on Slab Response under Contact Explosion
Authors: Anas S.M. , Alam Mehtab , Asatov Nurmuhamat , Djuraev Uktam
Published: March 2024

To design defense infrastructures and facilities, available prominent resources namely UFC 3-340-02, TM 5-1300, ASCE/SEI 59-11 and IS 4991, primarily consider test results from spherical explosives detonations whereas most of the explosives used in warfare and industrial/conventional operations have cylindrical/brick geometric form. Available research works in the literature considering various aspect ratios of cylinder TNT with its longitudinal axis perpendicular to the slab and of brick TNT having its length parallel to the supports and with its length and breadth in contact with the one-way slab, demonstrate that out of the three geometric forms (cylinder, sphere, and brick) of the explosive of the same mass; cylindrical explosive generates maximum pressure and the brick explosive produces the minimum. The authors discern that the obliqueness of the brick/cylindrical explosive with reference to the boundary condition of the slab influences the energy distribution and corresponding slab damage. In this paper, the effect of obliquely directed brick TNT explosive on slab response under contact explosion is examined in Abaqus software with a focus on comparing the slab damage and other responses with varying obliqueness of the explosive from 0° to 90° with increments of 22-1/2 degree. The numerical findings of the brick explosive having its length aligned with the slab supports demonstrate a strong correlation with the experimental results. The findings indicate that the maximum reflected pressure varies with the obliqueness of the brick explosive and consequently affects the slab damage including perforation size and geometry.
Creating a 3D terrain model for the territory of the Hasti-Imom ensemble in Tashkent, Uzbekistan
Authors: Schukina Olga , Abdukarimov Maksud , Valieva Albina
Published: March 2024

The purpose of this work is to create a three-dimensional model of the terrain on the territory of the Hasti-Imam ensemble of the city of Tashkent (Uzbekistan), using a Geoscan 401 multi-rotor unmanned aerial vehicle and a modern photogrammetric product Agisoft Metashape. Four flights were performed at this facility using a Geoscan 401 quadcopter. Aerial photography was carried out at different heights (from 40 m to 100 m) and with different inclinations of the aerial camera (45°, 60°, 90°) in order to display all elements of the ensemble in more detail. Aerial photography was carried out at a scale of 1:500 using a SonyDSC-RX1 digital aerial camera with a focal length of 50 mm. The longitudinal overlap of aerial photographs was from 70% to 80% and, accordingly, the transverse overlap was also from 70% to 80%. The number of aerial photographs at the site was 936 pieces. The length of all air routes was 65.9 km. The area of the filmed object was 14 hectares.The processing of unmanned aerial photography and the construction of a three-dimensional model of the terrain on the territory of the Hasti-Imam ensemble in Tashkent, Uzbekistan was carried out in the modern photogrammetric complex Agisoft Metashape.
Selective extraction of silver(I) and photometric determination di-(2-naphthyl)-thiocarbazone (dinaftizone) in the organic phase
Authors: Abdullaeva Dilnoza , Giyasov Anvar , Muratkulov Olimjon , Rakhmatova Nodira , Mengliev Sherzod , Zokirova Shokhista , Tursunov Dilshod , Turabdjanov Sadritdin
Published: March 2024

A method for the selective, simple and accelerated extraction-photometric determination of silver has been developed, based on the selective extraction of silver(I) from a strongly acidic medium in the presence of iodide ions and dimethylformamide and its complexation with dinaphthizone directly in the organic phase.The apparent molar extinction coefficient of the dinaphthizone complex of silver (I) at a maximum light absorption of 505 nm is 4.75·104. The calibration graph is linear in the range of 0.5-50 μg of silver (I) in 10 ml of extract. The determination of silver is not interfered with by large amounts of foreign ions in quantities up to 100,000 times within 2-5%. The extraction-photometric method developed for the determination of silver is recommended for analyzing silver content in diverse materials, including ores, rocks, industrial wastes, and other substances characterized by complex chemical compositions. Notably, this method is particularly advantageous as it eliminates the need for separating accompanying elements, streamlining the analytical process. By employing this extraction-photometric technique, analysts can achieve accurate and reliable results in the determination of silver content even in samples with intricate chemical matrices. This method enhances efficiency and expedites the analysis of materials that may contain a variety of elements besides silver.
Microbiological activity of soils with difficult ecological conditions
Authors: Nabiyeva Gulchekhra , Makhkamova Dilafruz , Kenjaev Yunus
Published: March 2024

This article presents data on irrigate d meadow-alluvial soils of the Takhtakupyr region of the Karakalpak Republic. The microbiological activity (ammonifiers, spore, oligonitrophils, nitrogen fixers, actinomycetes, microscopic fungi) of meadow-alluvial soils is studied, depending on the degree of salinity. The degree of enrichment with microorganisms of highly saline, medium and slightly saline soils is determined.
Study on the soil pollution condition around the domestic wastewater
Authors: Jabbarov Zafarjon , Atoyeva Gulkhayo , Sayitov Sardor , Kurvantaev Rakhmon , Khakimova Nodira , Makhammadiev Samad , Kenjaev Yunus , Makhkamova Dilafruz , Jobborov Bakhrom , Nabiyeva Gulchekhra , Nurgaliev Najmiddin , Aliboyeva Malika , Zakirova Salomat
Published: March 2024

The rapid development in the population of the earth, the increase in the level of consumption of people leads to an increase in the amount of household waste from year to year, which, in turn, increases the negative impact on the environment of their collection and storage areas, that is, household waste landfills. From these studies, the state of contamination of the soil as scattered around the municipal landfill, the sources factors affecting the contamination were described. The main purpose of the conducted research is to determine the level of pollution of the soil under the influence of household waste. The researches were conducted in the soil scattered around the Tashkent municipal waste dump, located in the Ohangaron district were of the Tashkent province. The results showed that in the chemical pollution of irrigated typical gray soils, the domestic landfill is considered the main pollutant source, and the level of pollution decreases from the distance of 1.2 km from the landfill, and into according to the soil layers, it decreases uniformly from the top to the bottom, starting from the 70 cm layer.The soil scattered around the landfill is contaminated with organic pollutants, ash elements and heavy metals and other pollutants, including the total amount of Cd 3.1 times, As 4.39 times, Sb 2.46 times compared to the permissible limit share. , W 4.6 times and other heavy metals increased to different degrees.
Cultivation of plants based on new technologies in the dry soil of the Aral Sea
Authors: Jabbarov Zafarjon , Abdrakhmanov Tokhtasin , Tashkuziev Maruf , Abdurakhmonov Nodirjon , Makhammadiev Samad , Fayzullaev Orzubek , Nomozov Urol , Kenjaev Yunus , Abdullaev Shokhrukh , Yagmurova Dilafruza , Abdushukurova Zamira , Iskhakova Shoira , Kováčik Peter
Published: March 2024

The article presents the results of research aimed at growing plants on the basis of different technologies in the relic-swamp salt-sand desert soils of the Aral Sea. The amount of annual precipitation on the soils of this area formed in the conditions of the arid climate region is 180-200 mm. Many factors should be taken into account for growing plants in these areas. It is necessary to choose a suitable halophyte plant for marshy saline soils and to take into consideration sharp changes in temperature throughout the season. Planting in these soils is due to atmospheric precipitation and groundwater. Therefore, experiments were carried out on plant cultivation in the pipe method, and the efficiency was up to 1.5 times higher than in conventional conditions. The combined use of different technologies with the pipeline method has further increased efficiency.
Study on physiobiological features of grain and contemporary storage methods
Authors: Turatbekova Aidai , Kuramboev Tokhir , Ergasheva Olimaxon , Kayumova Nasiba , Babayev Aziz , Jumanazarov Shahzod , Tasheva Umida
Published: March 2024

Grains are an important food that provides important nutrients. Due to the seasonality of grain crops, humanity has always looked for options for preserving grain. Proper grain storage is critical to maintaining grain quality, preventing spoilage and ensuring food security. The centuries-old experience of farmers shows that grain storage is a complex process that requires careful planning and management. Proper grain storage has several benefits. First, it helps prevent crop losses due to spoilage, pests and diseases. Secondly, it preserves the quality of the grain, ensuring its suitability for human and animal consumption. Thirdly, it allows you to regulate the supply of grain throughout the year, ensuring its availability even during periods of low harvest. As science and technology have advanced, new, efficient, and cost-effective techniques for storing grains have been put forth. Nevertheless, the issue of product quantity and quality safety during storage remains pertinent. This page gives a general overview of the different ways that grains can be stored, such as in warehouses, silos, and polyethylene sleeves. Each approach is discussed together with its benefits and drawbacks. Gaining an understanding of these procedures would enable stakeholders to design efficient storage plans and make well-informed decisions to guarantee grain supply and quality.
Egg color ratio change in a new genetic method developed for improving the mulberry silkworm (Bombyx Mori L.) balanced with embryonic z-lethality
Authors: Abdukadirov Murodkhuja , Nasirillaev Bakhtiyar , Rajabov Narzulla , Islamov Sokhib
Published: March 2024

The mulberry silkworm Bombyx mori L. is a rare insect that has been domesticated it for 5000 years and used to satisfy its needs. The Mulberry silkworm is one of the most convenient species for scientific research in terms of its structure, rearing, and rapid reproduction. In our study, the egg stage sex-linked balanced with embryonic Z-lethal (SLBL), the rare C-8ngl (NGL - new genetic line) breed of the mulberry silkworm Bombyx Mori L., was improved gradually with genetically simple strains with high technological traits. The balance of ℓ1 and ℓ2 embryonic non-allelic lethality linked with the Z chromosome in the F1, F2, and F3 generations was analyzed, and the extent to which they were in balance in each generation was determined. The female-to-male ratio in each generation was strictly checked at the egg stage. In the F1, F2, F3, and F4 generations obtained from backcross breeding, genetic schemes have been developed that show the degree to which embryonic lethal ℓ1 and ℓ2 linked to the Z chromosome are expressed in each generation. Using this genetic method, the balance of embryonic non-allelic genes was achieved in the selection line by the F4 generation, and as a result, a new line was obtained.
Animal trypanosomosis eliminated in a major livestock production region in Senegal following the eradication of a tsetse population
Authors: Seck Momar Talla , Fall Assane Guèye , Ciss Mamadou , Bakhoum Mame Thierno , Sall Baba , Gaye Adji Marème , Gimonneau Geoffrey , Bassène Mireille Djimangali , Lancelot Renaud , Vreysen Marc J.B. , Bouyer Jérémy
Published: March 2024

African animal trypanosomosis (AAT) was one of the main disease-related constraints to the development of intensive livestock production systems in the Niayes region of Senegal, a 30 km wide strip of land along the coast between Dakar and Saint-Louis. To overcome this constraint, the Government of Senegal initiated an area-wide integrated pest management programme combining chemical control tactics with the sterile insect technique to eradicate a population of the tsetse fly Glossina palpalis gambiensis Vanderplank, 1949 (Diptera, Glossinidae) in this area. The project was implemented following a phased conditional approach, and the target area was divided into three blocks treated sequentially. This study aims to assess the temporal dynamics of the prevalence of Trypanosoma spp. during the implementation of this programme. Between 2009 and 2022, 4,359 blood samples were collected from cattle and screened for trypanosomes using both the buffy coat and ELISA techniques, and PCR tests since 2020. The seroprevalence decreased from 18.9% (95%CI: 11.2–26.5) in 2009 to 0% in 2017–2022 in block 1, and from 92.9% (95%CI: 88.2–97) in 2010 to 0% in 2021 in block 2. The parasitological and serological data confirm the entomological monitoring results, i.e., that there is a high probability that the population of G. p. gambiensis has been eradicated from the Niayes and that the transmission of AAT has been interrupted in the treated area. These results indicate the effectiveness of the adopted approach and show that AAT can be sustainably removed through the creation of a zone free of G. p. gambiensis.