bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effectiveness of Direct Instructional Strategy on Speaking Skills Of 7th Grade At SMP Tri Dharma Palembang
Authors: Segara Bima , Iman Jaya Nur , Permana Dio Resta , Angraini Nike
Published: July 2024

This study was conducted to assess the English speaking proficiency of students. The students' English speaking achievement was abysmal. The aims of this study were to determine: (1) the extent of improvement in speaking skills with and without the use of the direct instructional strategy, and (2) whether there was a notable improvement in the speaking skills of students who received the direct instructional strategy compared to those who did not. This study employed quasi-experimental research methodology. A total of 16 students were selected as a sample, with 16 students assigned to the experimental class and another 16 students assigned to the control class. The data were gathered by the administration of an oral examination. The data were analysed using both paired sample t-tests and independent sample t-tests. Through data analysis, it was determined that there was a notable surge in pupils' proficiency in oral communication. The paired sample t-test yielded a t-test statistic of -28.428 and a significance value of 0.00, which was less than the predetermined significance level of α (0.05). This demonstrates an enhancement in students' oral communication abilities. Furthermore, the results of the independent sample t-test indicate that the calculated t-test value (-13.075) and the corresponding p-value (0.00) were both below the predetermined significance level (α) of 0.05. The results indicate a substantial disparity in the average speaking abilities of pupils who received teaching through the direct instruction technique compared to those who did not get such instruction.
The Association Between the Characteristics of Pregnant Women with Knowledge and Attitudes Toward Midwifery Care Based on Gender Sensitivity
Authors: Maryanah  , Sri Sukamti  , Aticeh
Published: July 2024

Respectful maternity care must be ensured that all pregnant women can accept it. It is necessary to understand all pregnant women receiving midwifery care with a gender-sensitive approach to prevent the possibility of mistreatment, harassment, or violence during midwifery practice. This study aimed to assess the association between the characteristics of pregnant women and the knowledge and attitudes regarding gender-sensitive midwifery care. This was a cross-sectional study on 200 pregnant women who came to get antenatal care services at independent practice midwives. The sample was selected using a purposive sampling technique. Multivariate logistic regression analysis was performed to obtain the odds ratio, 95% confidence interval, and p-value for the trend to assess the strength of the association. Data was collected using a questionnaire that was developed and has been assessed for validity and reliability. Pregnant women who actively participate in community activities are associated with good knowledge of midwifery care with a gender sensitivity approach (OR equal 1.51, OR equal 1.16-1.97, p-value equal 0.03). Pregnant women with higher education levels are associated with a good attitude toward midwifery care with a gender sensitivity approach (OR equal 2.02, 95% CI equal 1.01-4.05, p-value equal 0.04). Pregnant women participating in community activities are associated with good knowledge about midwifery care with a gender sensitivity approach, and pregnant women with higher education levels are associated with good attitudes about midwifery care with a gender sensitivity approach (p-value less than 0.001). Midwives and other health workers educate pregnant women in all health facilities at every antenatal visit and community activities such as the village community health center.
Mér fannst ég verða aftur ég sjálf
Authors: Björnsdóttir Íris , Karlsdóttir Sigfríður , Sigurðardóttir Sólrún
Published: July 2024

Tilgangur
Tilgangur þessarar rannsóknar var að afla aukinnar þekkingar á reynslu
kvenna af hormónauppbótarmeðferð á breytingaskeiði. Breytingaskeið
getur hafist allt að 10 árum áður en tíðahvörf skella á. Á þessu skeiði getur
konan upplifað ýmis líkamleg og andleg einkenni. Hormónameðferð tengd
breytingaskeiði er árangursríkur meðferðarmöguleiki til meðhöndlunar á
líkamlegri og andlegri vanlíðan.

Aðferð
Eigindleg fyrirbærafræðileg aðferð var valin og stuðst við
Vancouver-skólann í fyrirbærafræði. Þátttakendur voru 12 íslenskar
konur á aldrinum 47-53 ára sem höfðu verið á hormónauppbótarmeðferð
síðustu 3-24 mánuði og voru valdar með tilgangsúrtaki. Tekin voru 12
einstaklingsviðtöl, rituð upp orð fyrir orð og að lokum þemagreind.

Niðurstöður
Yfirþema rannsóknarinnar var: Mér fannst ég verða aftur ég sjálf. Jafnframt
voru sex meginþemu greind: Líkaminn varð aftur eins og ég þekkti hann,
Það kviknaði aftur á mér, Félagsleg tengsl byggð upp, Eftirsjá að tímanum
sem ég missti, Virk hlustun og samskipti og Þetta þroskar mann. Konurnar
greindu frá jákvæðum líkamlegum, andlegum og félagslegum breytingum
eftir að þær byrjuðu á hormónauppbótarmeðferð. Til dæmis hurfu verkir
í liðum og þær hvíldust betur á nóttunni sem var ein af ástæðum þess að
þær byrjuðu á hormónameðferð. Í rannsókninni kom fram að konurnar
hefðu viljað fá greiningu fyrr þar sem þær áttu nokkrar læknisheimsóknir
að baki og upplifðu eftirsjá að tímanum þegar þær voru að kljást við
einkenni breytingaskeiðs. Einnig hefðu þær viljað fá meiri skilning frá
fagfólki þegar þær leituðu eftir aðstoð.

Ályktun
Álykta má að hormónauppbótarmeðferð bæti verulega líkamlega-,
andlega- og félagslega líðan kvenna á breytingaskeiði. Mikilvægt
er að heilsugæslan komi til móts við konur sem eru að ganga í
gegnum breytingaskeiðið og bæti stuðning og fræðslu til þeirra um
breytingaskeiðið þannig að þær geti tekið upplýsta ákvörðun um ávinning
og áhættuþætti hormónauppbótarmeðferðar.

Lykilorð
Hormónauppbótarmeðferð, breytingaskeið, reynsla, konur, fyrirbærafræði
Screening of Secondary Metabolites, Antibacterial and Antioxidative Capacity of Paederia Foetida L. Leaf Extracts
Authors: Islam Md. Monirul , Ahmed A M Abu , Rahman Md. Atiar
Published: July 2024

Plant resources have been utilized since ancient times for the healing of various illnesses of humankind. This study investigated the secondary metabolites, antibacterial, and antioxidative capability of Paederia foetida L. (P. foetida) leaf extract. Qualitative tests were done to determine the presence of secondary metabolites. The disc diffusion method was used for the determination of the antibacterial activity of the extract. The DPPH (1, 1-diphenyl-2-picrylhydrazyl) free radical scavenging assay, reducing power assay, total phenolic, and total flavonoid content methods were followed for the evaluation of antioxidative potentials of the leaf extract. The leaf extract was found to show significant (p < 0.05) antibacterial activity against Gram-positive bacteria compared to Gram-negative ones. In DPPH free radical scavenging assay, the inhibitory concentration (IC50) value for methanol crude extract was found to be fairly significant (162.929 μg/mL) in comparison with that (1.57 µg/mL) of the reference standard ascorbic acid. The maximum absorbance for reducing power assay was 0.823 compared to 1.891 for standard ascorbic acid. The extract was found to have a total phenolic content of 8.03 ±1. 05 mg/g gallic acid equivalent and flavonoid content 134.74 mg/g quercetin equivalent. The results demonstrated a moderate antibacterial and promising antioxidative activity of P. foetida leaf extract, but it is necessary to further analyze prospective pharmaceutical preparation.
The Chittagong Univ. J. B. Sci.,Vol. 10(1 &2):121-137, 2020
Geo-Spatial Investigation of Climate Change Impacts on Irrigation Demand of Dry Season Boro Rice in Northwest Bangladesh
Authors: Khan Nazifa Rahman , Rahman Md Atiqur
Published: July 2024

The present study is an attempt to assess the irrigation demand of the dry season Boro rice in the northwest regions of Bangladesh using climatic, soil and crop data. The FAO-56 Penman–Monteith method was applied to calculate reference evapotranspiration and irrigation demand of Boro rice has been estimated using CROPWAT model. Both the observed and downscaled Representative Concentration Pathway (RCP) climatic data were used in the study. The result reveals that there is no significant change in irrigation demand of Boro rice from 1975 to present. However, the demand will increase significantly in future. The study projects that future irrigation demand of Boro rice in climate change situation for RCP 8.5 will be increased by 180-220 mm in 2075. It is expected that the findings will contribute in devising appropriate agricultural and irrigation plans for the region.
The Chittagong Univ. J. B. Sci.,Vol. 10(1 &2):217-235, 2020
Stress and Burnout in Undergraduate Medical Students
Authors: Shamsad Iffat Ara
Published: July 2024

Abstract not available
J Dhaka Med Coll. 2022; 31(2) : 170-172
Assessment of Quality of Life Among Patients With Knee Osteoarthritis
Authors: Islam Md Hasibul , Ahmed Badrunnesa , Alam Mohammad Shafiqul , Gomes Lilian Catherene , Khandaker Md Nuruzzaman , Islam Md Khairul
Published: July 2024

Introduction: Osteoarthritis (OA) is a degenerative joint disease estimated to be the fourth leading cause of disability. Methodology: We conducted a cross-sectional observational study at BSMMU, Dhaka, from April 2018 to March 2019. Our goal was to evaluate the quality of life in knee OA patients in Bangladesh using Short Form-36 (SF-36) Health Survey and Western Ontario and McMaster Universities Osteoarthritis (WOMAC) Index. We collected data through face-to-face interviews, adhering to specific inclusion and exclusion criteria. Results: Most participants were within the 40-59 year age group, with 65.2% of patients reporting a disease duration of 1-5 years. The mean WOMAC scores differed significantly by age (p=0.001), with older patients having higher scores. Gender and monthly income did not significantly impact WOMAC scores (p>0.05). Educational status showed potential significance (p=0.074), but it did not reach statistical significance. There was a strong statistical association between total WOMAC scores and patient age (p=0.001). However, other socio-demographic factors showed no significant differences (p>0.05). Patients with shorter OA knee durations (less than one year) had notably lower WOMAC scores than those with longer durations (1-5 years), with a significant difference (F=16.513, p<0.001). In terms of OA knee grading, patients with more severe OA (grade III) had significantly higher WOMAC scores than those with less severe OA (grade I or II) (F=190.077, p<0.001). Gender, educational status, and monthly income significantly influenced SF-36 scores in knee OA patients. Male patients and those with higher educational levels reported higher SF-36 scores. Monthly income also had a significant effect (F=6.101, p=0.004), with higher income linked to higher SF-36 scores. Age did not significantly impact SF-36 scores (F=0.492, p=0.614). Body mass index (BMI) did not significantly affect health-related quality of life in OA knee patients. The elderly with more advanced and prolonged disease had lower quality of life according to WOMAC. Conclusion: It can be concluded that patients with OA knee had relatively poor quality of life in physical health component than that of mental health component and role physical domain was mostly affected among all domains.
J Dhaka Med Coll. 2022; 31(2) : 201-209
Neurodevelopment Outcome among Preterm Infants Admitted in Neonatal Intensive Care Unit
Authors: Jahan Mosammad Alpana , Shuma Afroza Islam , Sultana Rabeya , Rumman  , Jahan Ismat , Shabuj Mohammad Kamrul Hassan , Dey Sanjoy Kumer , M A Mannan  , Shahidullah Mohammod
Published: July 2024

Introduction: With increasing the survival rates of premature babies, the management of long term complications, especially neurodevelopmental disorder is becoming an important issue for a better life.
Aims: To assess the factors associated with adverse neurodevelopment outcome among preterm
infants admitted in Neonatal Intensive Care Unit (NICU).
Methods and Material: This prospective cohort study was conducted in Department of Neonatology, BSMMU, Dhaka, Bangladesh. Premature infants (<34 weeks) discharged from the NICU were enrolled and followed up for neurodevelopmental assessment at 6 months of age. Prenatal, perinatal, and postnatal features of the babies were recorded. The Bayley-III scale was used to assess the composite scores. Continuous variables were analyzed using an independent t-test and categorical variables with chi-square test. Logistic regression analysis was performed to find out the relationship of risk factors with neurodevelopmental scores.
Results: A total 47 patients were analysed at 6 months of age using Bayley scale III. Mean birth weight and gestational age was 1595.11 ± 377.17g and 32.43 ± 1.48 weeks respectively. Mean cognitive, motor and language score were 80.79±14.51, 82.87±14.53 and 82.98±13.72 respectively. Despite the fact that all mean scores were normal, 27.7% of infants in cognition, 23.4% in motor, and 31.9% in language had a BSID-III value < 70. Variables like gestational age < 30 weeks, birth weight <1500 grams, and convulsion have been linked to poor neurodevelopmental outcomes. However, regression analysis revealed none of them were significant.
Conclusions: In our study, at six months of age, the cognitive, language, and motor scores of preterm newborns (less than 34 weeks of gestation) were within normal limits. Of the newborns, we observed that 27.7% had cognitive delay and 31.9% experienced language delay.
J Dhaka Med Coll. 2022; 31(2) : 251-257
Systematic Review: Particle Swarm Optimization (PSO) based Load Balancing for Cloud Computing
Authors: Syed Darakhshan , Muhammad Shaikh Ghulam , Rizvi Safdar
Published: July 2024

In this modern era cloud computing and widespread use of it have led to a massive spike in users' requests. The infrastructure's resources would either not be able to handle the increased volume of traffic or the scenario would lead to some resources being over or underutilized. Due to the unpredictable spike in traffic the system’s performance eventually grades. An optimal load distribution is therefore the area of concern for controlling traffic so that all available resources are fully used if possible in order to increase system efficiency. Static, heuristics-based, traditional dynamic and metaheuristic-based algorithms are ways that have been used for effective load balancing. The issue is challenging since there isn't a single best fit approach. The objective of this systematic review is to study the utilization of Particle Swarm Optimization method along with its proposed variations to distribute the incoming traffic evenly with efficient resource utilization.
Energy, Society and Sociodemographic Constraints Nexus: Development and Future Prospects
Authors: Saleem Leezna , Intikhab Ulfat
Published: July 2024

To overcome the challenges faced by the energy sector, policymakers need to prioritize the development of strategic policies that promote the adoption of waste-to-energy technologies, Tidal energy, solar power systems, and wind farms. These policies should emphasize the integration of renewable energy sources into the existing energy infrastructure, ensuring a more sustainable and resilient energy supply for urban areas. The study underscores the importance of collaboration between various stakeholders, including government bodies, private sector entities, and local communities. By fostering partnerships and creating incentives, it becomes possible to mobilize resources and expertise towards the implementation of renewable energy projects. This collaboration would not only address the energy crisis but also contribute to job creation and overall socioeconomic development. Proper utilization of renewable energy resources can resolve the dilemma of energy crises in the country. According to our results, solar stood first in the overall ranking followed by Tidal, waste-to-energy, and wind energies. Solar performed better in indigenous manufacturing and development, resource potential, and technological development. Pakistan has abundant green energy resources which could be utilized by the formation of a proper policy roadmap and mitigation of policy pathways to overcome the hazardous dependence on fossil fuels for energy requirements. The implementation of policies adopted should be assured to achieve energy sustainability
Museos universitarios: investigación, educación y transferencia del conocimiento. La aportación del MUA
Authors: Navarro Mondéjar Remedios , Alpañez Serrano David
Published: July 2024

El MUA es un proyecto vanguardista dentro del panorama universitario español, notable por su arquitectura innovadora y su enfoque museográfico, que presenta exposiciones permanentes y temporales de naturaleza científica, artística y patrimonial. 
Fundado en 1999, el MUA se concibe como una herramienta esencial para proporcionar una formación integral al alumnado universitario, mediante actividades que estimulen su sensibilidad y les ofrezcan una comprensión más profunda de nuestra condición, sociedad e historia.
 
El principal objetivo del MUA es erigirse como un centro de dinamización cultural, aprendizaje, encuentro y diálogo, acercando la innovación y la experimentación propias del entorno universitario y del arte contemporáneo a toda la sociedad.
 
Cada temporada, el MUA organiza una quincena de exposiciones temporales, que abarcan muestras de arte contemporáneo, actividades de divulgación de la investigación universitaria y proyectos institucionales que involucran a toda la comunidad alicantina, convirtiéndose en un difusor de conocimiento y un catalizador de la vida cultural de la comunidad.
Como museo universitario, el MUA presta una especial atención a la labor educativa a través de su Área Didáctica, estableciéndose como un espacio de aprendizaje y formación para el alumnado universitario así como para la comunidad educativa de la provincia de Alicante, que participa en nuestros talleres didácticos y visitas guiadas dirigidas a alumnado desde infantil hasta bachillerato, ciclos formativos y educación especial.
Pelatihan Pembuatan Media Pembelajaran Powerpoint Interaktif dan Aplikasinya Menggunakan Android
Authors: Fhadli Muhammad , Sabaruddin Sabaruddin , Sultan Mufti Amir
Published: July 2024

Program Pengabdian Masyarakat (PKM) ini bertujuan untuk meningkatkan skill guruSekolah Dasar Islam Terpadu Insantama Ternate dalam memberikan pembelajaran secaramenarik. Hal ini dilatarbelakangi oleh minimnya kemampuan guru dalam memberikanmedia pembelajaran interaktif yang dapat menarik siswanya. Dalam hal metode pelatihanyang diterapkan adalah pelatihan praktik langsung serta didukung juga oleh video tutorial.Tahapan yang dilakukan terdiri dari 3 tahapan yaitu tahap persiapan, tahap pelaksanaandan tahap pasca kegiatan. Hasil dari pengabdianan ini didapatkan bahwa Pelatihanpembelajaran powerpoint di Sekolah Dasar Islam Terpadu Insantama Ternate berlangsungdengan baik dan mampu meningkatkan kualitas guru Sekolah Dasar Islam TerpaduInsantama Ternate dan Pelatihan media pembelajaran powerpoint interaktif berbasisandroid ini terkati dengan upaya peningkatan literas
Breastfeeding Discourses Through Thai Narratives from 1932 to 2022
Authors: Chutipanyabut Yossapol , Akarachantachote Preeda
Published: July 2024

This textual analysis examines mother-related narratives published between 1932 and 2022 from education and entertainment-based media as well as from traditional and modern social media platforms, to study the discontinuity and construction of breastfeeding discourses in the media. The results show that the discourses rupture into five eras: (1) Pre-framework era: Buddhist mythologies infuse the signification of breastmilk as the product of a mother’s love and blood. The spirit of the mother runs in breastmilk, signifying a wet nurse as a mother-status. (2) Breastmilk is the food from nature: The spirit of the mother runs in the biological mother’s breastmilk, no longer from a wet nurse. (3) Breastmilk is inferior to infant formula: The power of advertisements and the knowledge of nutritional science makes infant formula become the dominant choice for middle-class mothers as it symbolizes rich and smart mothers. (4) Breastmilk is best: The knowledge of medical science with the power of authority controlled over all media platforms sees a return to breastfeeding domination, in which significated infant formula is viewed as poison and non-breastfeeding mothers are viewed as impatient and uneducated. (5) Breastmilk is ideal, but negotiable: With the influence of social media that breaks the discourses into several spheres, one group realizes and avoids the use of binary oppositions to depreciate bottle-feeding mothers, while the other objectifies breastmilk as though it is an industrialized product in which every breastmilk has the same property. The researchers found out that the breastfeeding discourses throughout the history of Thai culture represents the interaction between Buddhist mythologies and Western science, the middle-class mothers are influenced by the upper-class in every era, while capitalism and patriarchy find a way to engrave in both infant formula and breastfeeding in the form of advertising and publicity.
Analysis of The Effect of Corporate Governance on Company Performance with Working Capital as A Mediating Variable (Study on Manufacturing Companies in Indonesia)
Authors: Ardira Givantoro Agma , Hersugondo Hersugondo
Published: July 2024

This study aims to examine the effect of Corporate Governance (CG) consisting of Board Independence (BI), Board Diversity (BD), Return on Assets (ROA), and Return on Equity (ROE) mediated by the Working Capital (WC) at Indonesia Manufacture Company during the current year 2019–2021. Purposive sampling method was used to determine the number of research samples. With a total sample of 63 samples from 2019–2021. The analytical technique used is multiple linear regression for each research model with the SPSS:25 program which previously passed the classical assumption test. The results in this study, BI has a positive and not significant effect on WC and BD has a positive and significant effect on WC. Variable BI has a positive and not significant effect. ROA and BD have a positive and not significant effect on ROA and WC has no effect on ROA then finally in the third model the BD has a positive and significant effect on ROE. Variable BD has a positive and significant effect on ROE and then the last variable WC has no effect on ROE.Keywords:Corporate Governance, Working Capital, Firm performance
The Influence of Career Development, Organizational Climate, And Motivation on Employee Performance at Sidenreng Rappang Regency Water Resources Management Office
Authors: Alwany Haeranah , Maryadi Maryadi , Setiawan Irfan , Herni Herni
Published: July 2024

The research aimed to examine the effect of career development, organizational climate, and work motivation on employee performance at the Sidenreng Rappang Regency Water Resources Management Office. The process was through the application of a quantitative method by collecting data from two important sources. The primary data were collected by distributing questionnaires to 52 respondents while secondary sources included official documents from related agencies. The data collected were analyzed using statistical methods to identify the relationship between the variables. The analysis was initiated through a Validity and Reliability test followed by Multiple Linear Regression, Hypothesis Test, and Partial t-test to evaluate the hypothesis proposed. The results showed that career development, a positive organizational climate, and high work motivation significantly influenced employee performance. This showed that the sustainable and structured combination of the three factors could increase collective employee performance and assist in achieving organizational goals.
PEMBUATAN SISTEM INFORMASI BRANDING DAN MARKETING KAWASAN USAHA MIKRO KECIL MENENGAH YANG BERSINERGI DENGAN KEGIATAN WISATA, PENDIDIKAN KELUARGA (DEWI PELAGA) DI CEMOROKANDANG MALANG
Authors: Mentari Mustika , Asmara Rosa Andrie , Amalia Eka Larasati , Lestari Vivin Ayu , Ulfa Farida , Rahman Mochamad Faisal , Sabita Almira Rahma , Ardiansyah Muhammad Rizqi , Fitriana Aliza Rizqi
Published: July 2024

The geographical area of Cemorokandang village in Malang has a set of potential Small and Medium Enterprises (SMEs) that have been running for a long time but require technological support in branding and marketing. Currently, most SME groups in Cemorokandang village use the traditional method by entrusting the goods produced to shops around the area. The SMEs are in Dewi Pelaga (Desa Wisata Pendidikan Keluarga). Other potentials owned by Cemorokandang village that need to be managed are the potential for sports, tourism, and education potential. This potential needs to be promoted so that many people know it better. Therefore, it is necessary to have a branding and marketing information system that contains pages describing the potential of SMEs and other support such as sports, education, and tourism tracking places. The website that has been created has been tested, and results were obtained on the point that "The community services activities carried out really provide solutions to the problems faced by partners." Some 75% of partners gave a strongly agreed response, while the other 25% gave an agreeing response. From these results, it can be said that this information system is effective in branding and marketing products owned by SMEs in the Dewi Pelaga area.
PELATIHAN PENGEMBANGAN KONTEN DIGITAL MENGGUNAKAN ALAT DESAIN BERBASIS WEB DAN MOBILE
Authors: Rachmad Syulistyo Arie , Ni’ma Shoumi Milyun , Enggar Sukmana Septian , Rahmad Cahya , Retno Tri Hayati Ririd Ariadi , Nur Rahmanto Anugrah , Zettyara Devi
Published: July 2024

The internet and information systems are rapidly evolving, with technology becoming increasingly sophisticated worldwide. Consequently, entrepreneurs can now offer valuable information or conduct business from the convenience of their own homes. In this context, it is expected that PKK mothers, specifically those affiliated with the PKK group RW 07 in Purwodadi Village, Blimbing District, Malang City, should seize these opportunities by utilizing digital content. The PKM Community Service Team is encouraged to offer training in digital content creation in light of advancements in information technology. The team is currently seeking web-based and mobile design tools that can be readily utilised by PKK group mothers. The digital content produced can be employed to advertise activities within the RW community or their own merchandise. Following the implementation of community service, the PKM team evaluated the PKK group with 5 questions. The PKK group deems the presented material useful and the program beneficial for enhancing their skills. Overall, the PKK group expresses satisfaction with the program's implementation. Additionally, following observations made by the PKM Team, the information we offer has been utilized to produce captivating content for broadcasting announcements on social media platforms belonging to the PKK organization.
PENDAMPINGAN PENGURUSAN IZIN PIRT UMKM JAMU WR9 DI DESA WRINGINSONGO KECAMATAN TUMPANG KABUPATEN MALANG
Authors: Mundzir Hudriyah , Hadiwinata Khrisna , Muslim Shohib , Rizza Muhammad Akhlis , Anshori Mohammad Abdullah , Zakaria Muhammad Nanak
Published: July 2024

Community service activities were carried out in Tumpang District, Malang Regency with partners, namely UMKM Jamu WR9 which is a representative of MSMEs in Wringinsongo Village, Tumpang District, Malang Regency. These business actors include the production and sales processes. Community service activities are carried out with the aim of providing understanding to business actors regarding the factors supporting business activities, namely legality and business management factors, in this case PIRT licensing so that business activities carried out are not only profit-oriented, but business activities can continue to develop in the future. by paying attention to and implementing supporting factors for business activities and by providing assistance with PIRT licensing. The activity implementation method consists of three stages. The first preparation stage includes pre-survey, team formation, proposal creation and submission, team and partner coordination as well as preparation of tools and materials to assist PIRT licensing. The second stage is the program implementation stage in the form of assistance which begins with discussion and preparation for PIRT management by providing a sealer machine and stove. The third stage is the evaluation and reporting stage. Evaluation is carried out by comparing the conditions of partners before and after program implementation using interview and observation methods. After that, a report is prepared for subsequent publication. With the implementation of this program, there will be an improvement in society's value order in the field of education, especially in the fields of economics and law.
 
Keywords: PIRT permit, UMKM
Pelatihan Pembuatan Biochar dari Sampah Organik di Desa Wringinsongo Kecamatan Tumpang Kabupaten Malang
Authors: Zamrudy Windi , Iswara Mochammad Agung Indra , Chalim Abdul
Published: July 2024

Wringinsongo Village is one of the partner villages of the Malang State Polytechnic. Located in Malang District and the distance is 18 KM from Malang State Polytechnic. Recently, the problem faced by residents is the amount of garbage caused by the large number of people who inhabit the village, the emergence of tourism sites, and the increasing lifestyle. The emergence of garbage in the yard causes new problems for the social environment, so it needs serious attention. Meanwhile, in the area there are already Temporary Disposal Sites (TPS) and Final Disposal Sites (TPA), but if people just throw garbage continuously the garbage will build up. However, if the community is provided with procedures for processing and managing waste first, then the amount of waste can be reduced. One of the impacts of the development of natural bathing tourism in Wringinsongo village is the emergence of waste problems left by visitors to these tourist attractions. For this reason, it is necessary to find an alternative solution that is easy to do safe for the environment, and does not cause a new impact, which is to be processed into fuel by drying and processing it into biochar. With this technical guidance, it is hoped that it can become an insight into new knowledge of technology development that can be developed on a large scale to overcome the waste problem.
PELATIHAN DAN PENDAMPINGAN DIGITALISASI ADMINISTRASI PENJUALAN PADA KELOMPOK WANITA TANI " DEWI SARTIKA" DESA PETUNG SEWU KABUPATEN MALANG
Authors: Suwarni Evi , Zuraida Vit , Amanda Tiara Estu , Ernawati Widi Dwi , Akmalia Masitha Nisa
Published: July 2024

This Community Service aims to provide assistance and training for the Petung Sewu Village Farmer Women's Group, Malang Regency, namely the Petung Sewu Village farmer women's association that processes citrus drinks which currently does not have proper business administration records, resulting in irregular recording and proof documents, inseparability between personal money and business capital and business results,  In fact, often it cannot be known the profit and loss from the proceeds of sales. This community service activity is in the form of assistance to the Petung Sewu Village Farmer Women's Group, Malang Regency in terms of managing business administration activities systematically using the TemanBisnis application to facilitate the management of administrative activities so that all administrative activities can be recorded properly. The method used is to hold assistance and training on the use of digital financial administration records, namely the "Business Friends" application. The end result of this activity is the application of a good digital sales administration system to realize an orderly administrative business and ease of financial records, financial statements. Real time information in this system helps the business operations of the Farmer Women's Group of Petung Sewu Village, Malang Regency more effectively and efficiently.
Keywords: Farmer Women's Group, Digital Sales Administration, TemanBisnis
Protective Measures for Sharing the Finnish DarkWeb Marketplace Corpus (FINDarC)
Authors: Lind´en Krister , Ruokolainen Teemu , H¨am¨al¨ainen Lasse , Harviainen J. Tuomas , Matthiesen Martin , Lennes Mietta
Published: July 2024

We discuss the archiving procedure of a corpus comprising posts submitted to Torilauta, a Finnish dark web marketplace website. The site was active from 2017 to 2021 and during this time one of the most prominent online illegal narcotics markets in Finland. A reduced version of the corpus, Finnish Dark Web Marketplace Corpus (FINDarC), has been archived in the Language Bank of Finland. In the current work, we focus on the protective measures for storing the data and how researchers can apply for access rights to the corpus under the CLARIN RES licence.
MEMAHAMI PENGATURAN PERKEMBANGAN DAN KEBIJAKAN HUKUM LINGKUNGAN
Authors: - Ukas - , Bakri Nofrizal , Agnesia Pera
Published: July 2024

Peraturan Perundang-undangan pada waktu zaman Hindia Belanda sebagaimana tercantum dalam Himpunan Peraturan Perundang-undangan di bidang Lingkungan Hidup yang disusun oleh Panitia Perumus dan Rencana Kerja bagi Pemerintah di bidang Pengembangan Lingkungan Hidup dan telah diterbitkan pada  5 Juni 1978. peraturan umum dalam rangka melakukan perikanan siput mutiara, kulit mutiara, teripang, dan bunga karang dalam jarak tidak lebih dari 3 mil-laut Inggris dari pantai-pantai Hindia Belanda (Indonesia). Pembangunan hukum lingkungan itu harus berdasaarkan Peraturan Perundang-undangan yang ada termasuk beberapa hasil konferensi secara global-general, memelihara dan megelolah lingkungan hidup harus dilandasai pembangunan dan kebijakan  yang berwawasan  lingkungan yang  penuh arti.
UNFAIR TRADE PRACTICES DAN ANTI-DUMPING CODE
Authors: - Ukas - , Husna Lenny
Published: July 2024

Untuk mengatasi praktik anti-dumping atau irasionalitas penerapan  Pasal VI GATT.  GATT telah membentuk Anti-Dumping Code yaitu suatu Code yang diarahkan kepada pengusaha untuk membatasi kemungkinan penyimpangan penerapan Pasal VI GATT.  Masyarakat bisnis perlu mengetahui ketetuan serta mekanisme penerapan ketentuan tersebut agar menghindarkan diri dari praktik bisnis curang, serta dapat menggunakan ketentuan Pasal tersebut di atas sebagai perisai untuk melindungi kepentingan bisnisnya, suatu proses pemeriksaan tuduhan saja, sudah cukup untuk mengacaukan prediksi bisnis suatu perusahaan, karena sering memakan rentang waktu yang sulit ditentukan sehingga berpengaruh terhadap biaya pemasaran dan rentang peluang pasar.
KEBIJAKAN PERDAGANGAN INTERNASIONAL DALAM PEMBANGUNAN HUKUM EKONOMI NASIONAL
Authors: Ukas Ukas , Husna Lenny , Arman Zuhdi
Published: July 2024

Trade Facilitation Agreement WTO merupakan langkah maju yang penting dalam sistem perdagangan internasional dan memberikan harapan baru bagi relevansi WTO. TFA adalah perjanjian multilateral pertama sejak pembentukan WTO pada tahun 1995 dan mencakup inisiatif baru untuk membantu negara-negara berkembang membangun kapasitas sambil juga menangani masalah peraturan di antara anggota WTO. TFA harus ditafsirkan dengan benar, ini adalah kombinasi dari langkah-langkah peningkatan kapasitas, fokus pada peningkatan teknologi dan persyaratan politik, termasuk kebijakan masing-masing negara, yang diperlukan untuk mengelola perdagangan luar negeri. Kehadiran asam lemak trans juga diduga dapat mengurangi biaya perdagangan lintas batas, sekaligus meningkatkan perdagangan dengan negara berkembang dan memungkinkan anggota WTO untuk mengelola arus perdagangan dengan lebih baik melalui proses harmonisasi dan regulasi politik. Artikel ini mengkaji tentang teori hukum dan asas serta aturan yang berkaitan dengan hukum dagang internasional dengan menggunakan metode analisis normatif kualitatif. Penulis menganalisis permasalahan yang berkaitan dengan pengoperasian perjanjian fasilitasi perdagangan di dalam WTO dan implementasinya di Indonesia. Dengan demikian, dapat disimpulkan bahwa: Pertama, pelaksanaan kebijakan perdagangan internasional yang berbasis pada keberadaan asam lemak trans di Indonesia memiliki dampak yang signifikan dan penting bagi perdagangan internasional, khususnya yang berkaitan dengan anggota WTO, termasuk Indonesia. Kedua, pengaturan normatif TFA di Indonesia diatur oleh beberapa undang- undang, baik undang-undang maupun keputusan presiden, sehingga pelaksanaan keberadaan TFA berdampak pada pengendalian perdagangan   luar   negeri   dan   kebijakan   ekspor-impor.
Forecasting ocean hypoxia in salmonid fish farms
Authors: Cerqueira Vitor , Pimentel João , Korus Jennie , Bravo Francisco , Amorim Joana , Oliveira Mariana , Swanson Andrew , Filgueira Ramón , Grant Jon , Torgo Luis
Published: July 2024

Introduction

Hypoxia is defined as a critically low-oxygen condition of water, which, if prolonged, can be harmful to fish and many other aquatic species. In the context of ocean salmon fish farming, early detection of hypoxia events is critical for farm managers to mitigate these events to reduce fish stress, however in complex natural systems accurate forecasting tools are limited. The goal of this research is to use a machine learning approach to forecast oxygen concentration and predict hypoxia events in marine net-pen salmon farms.

Methods

The developed model is based on gradient boosting and works in two stages. First, we apply auto-regression to build a forecasting model that predicts oxygen concentration levels within a cage. We take a global forecasting approach by building a model using the historical data provided by sensors at several marine fish farms located in eastern Canada. Then, the forecasts are transformed into binary probabilities that indicate the likelihood of a low-oxygen event. We leverage the cumulative distribution function to compute these probabilities.

Results and discussion

We tested our model in a case study that included several cages across 14 fish farms. The experiments suggest that the model can detect future hypoxic events with a commercially acceptable false alarm rate. The resulting probabilistic predictions and oxygen concentration forecasts can help salmon farmers to prioritize resources, and reduce harm to crops.
Pathoimmunological analyses of fatal E11 infection in premature infants
Authors: Luo Wei , Wang Lixia , Chen Zhengrong , Liu Ming , Zhao Yixue , Wu Yucan , Huang Bing , Wang Ping
Published: July 2024

E11 causes acute fulminant hepatitis in newborns. We investigated the pathological changes of different tissues from premature male twins who died due to E11 infection. The E11 expression level was higher in the liver than in other tissues. IP10 was upregulated in liver tissue in the patient group, and might be regulated by IFNAR and IRF7, whereas IFNα was regulated by IFNAR or IRF5.
Clinical characteristics and risk factors for mortality in pneumonia-associated acute respiratory distress syndrome patients: a single center retrospective cohort study
Authors: Li Junlu , Zhou Jiaxin , Tan Yingshuai , Hu Chunling , Meng Qingshan , Gao Jing , Xing Lihua
Published: July 2024

Background

Pathogenic diversity may have contributed to the high mortality of pneumonia-associated acute respiratory distress syndrome (p-ARDS). Metagenomics next-generation sequencing (mNGS) serves as a valuable diagnostic tool for early pathogen identification. However, its clinical utility in p-ARDS remains understudied. There are still limited researches on the etiology, clinical characteristics and risk factors for 28-day mortality in p-ARDS patients.

Methods

A single center retrospective cohort study of 75 p-ARDS patients was conducted. Patients were categorized into survival and deceased groups based on their 28-day outcomes. A comprehensive clinical evaluation was conducted, including baseline characteristics, laboratory indicators, outcomes and pathogen identification by mNGS and traditional microbiological testing. We then evaluated the diagnostic value of mNGS and identified clinical characteristics and risk factors for 28-day mortality in p-ARDS.

Result

The overall ICU mortality was 26.67%, and the 28-day mortality was 57.33%, with 32 cases (42.67%) in the survival group, and 43 cases (57.33%) in the deceased group. Patients in the deceased group were older than those in the survival group (68(59,73) years vs. 59(44,67) years, P=0.04). The average lengths of ICU and hospital stay were 9(5,13) days and 14(7,21) days, respectively. The survival group had longer lengths of ICU and hospital stay (ICU: 11(7,17) days and hospital: 17(9,27) days) compared to the deceased group (ICU: 8(4,11) days and hospital: 12(6,19) days) (P<0.05). Survival patients exhibited lower Acute Physiology and Chronic Health Evaluation (APACHE) II score on the 3rd and 7th days, higher lymphocyte counts, higher CD3+ and CD8+ T cell counts compared to deceased patients (P<0.05). Multivariate logistic regression analysis identified age, APACHE II scores on 3rd and 7th days, CD8+ T cell count and length of ICU as independent risk factors for 28-day mortality in p-ARDS patients. mNGS demonstrated a significantly higher overall pathogen detection rate (70/75, 93.33%) compared to the traditional method (50/75, 66.67%, P=0.022). The average turnaround time (TAT) for mNGS was significantly shorter at 1(1,1) day compared to 4(3,5) days for the traditional method (P<0.001).

Conclusion

Metagenome next-generation sequencing can be used as a valuable tool for identifying pathogens in p-ARDS, reducing diagnostic time and improving accuracy. Early application of mNGS alongside traditional methods is recommended for p-ARDS. Furthermore, older age, higher APACHE II scores, lower lymphocyte counts and lymphocyte subset counts were associated with increased mortality in p-ARDS patients, highlighting the importance of timely assessment of immune status and disease severity, especially in elderly.
Bacterial aggregation facilitates internalin-mediated invasion of Listeria monocytogenes
Authors: Feltham Liam , Moran Josephine , Goldrick Marie , Lord Elizabeth , Spiller David G. , Cavet Jennifer S. , Muldoon Mark , Roberts Ian. S. , Paszek Pawel
Published: July 2024

Dissemination of food-borne L. monocytogenes in the host relies on internalin-mediated invasion, but the underlying invasion strategies remain elusive. Here we use live-cell microscopy to follow single cell interactions between individual human cells and L. monocytogenes and elucidate mechanisms associated with internalin B (InlB)-mediated invasion. We demonstrate that whilst a replicative invasion of nonphagocytic cells is a rare event even at high multiplicities of invasion, L. monocytogenes overcomes this by utilising a strategy relaying on PrfA-mediated ActA-based aggregation. We show that L. monocytogenes forms aggregates in extracellular host cell environment, which promote approximately 5-fold more host cell adhesions than the non-aggregating actA-ΔC mutant (which lacks the C-terminus coding region), with the adhering bacteria inducing 3-fold more intracellular invasions. Aggregation is associated with robust MET tyrosine kinase receptor clustering in the host cells, a hallmark of InlB-mediated invasion, something not observed with the actA-ΔC mutant. Finally, we show via RNA-seq analyses that aggregation involves a global adaptive response to host cell environment (including iron depletion), resulting in metabolic changes in L. monocytogenes and upregulation of the PrfA virulence regulon. Overall, our analyses provide new mechanistic insights into internalin-mediated host-pathogen interactions of L. monocytogenes.
Assessment of left atrial function provides incremental value: the left atrial volumetric/mechanical coupling index in patients with chronic kidney disease
Authors: Ji Liqin , Gao Xue , Xiao Weiwei , Yu Shaomei
Published: July 2024

Background

Heart failure is a common cause of adverse cardiovascular outcomes in patients with chronic kidney disease (CKD). Left atrial (LA) characteristics are thought to be involved in the development of heart failure. However, LA assessment is complex. Though a variety of parameters have been defined, there is no single parameter that best defines LA function. Pilot data indicate that left atrial volumetric/mechanical coupling index (LACI) may be useful, but data with CKD are lacking.

Aim

The objective of this study was to define LACI in a cohort of patients with CKD and to assess its value in evaluating LA function and predicting heart failure.

Methods

A cohort of patients with CKD was enrolled at our hospital between 2021 and 2023. Follow-up was performed for heart failure. LACI is a volumetric to mechanical coupling index, calculated as the ratio of the LA volume index to the tissue-Doppler myocardial velocity at atrial contraction. Spearman’s rank correlation or Pearson’s correlation was used to calculate the correlation between LACI and echocardiographic/hemodynamic variables. Receiver operating characteristic curve (ROC) analysis was utilised to derive the area under the curve (AUC) for LACI, LVGLS, LASr, LASct and LASI for the detection of heart failure. Kaplan-Meier survival curves were employed to compare clinical outcomes based on LACI thresholds. A multivariable logistic regression analysis was employed to assess the relationship between risk factors and elevated LACI. Cox proportional hazards regression was used to identify risk factors for heart failure.

Results

LACI showed a positive correlation with NT-proBNP, CK-MB, LAVI, E/e’ and LASI (r = 0.504, 0.536, 0.856, 0.541 and 0.509, p < 0.001); and a negative correlation with LASr (r = −0.509, p < 0.001). On the ROC analysis for the determination of heart failure, the AUC of LACI was comparable to those of LVGLS (0.588 vs. 509, p = 0.464), LASr (0.588 vs. 0.448, p = 0.132), LASct (0.588 vs. 0.566, p = 0.971) and LASI (0.588 vs. 0.570, p = 0.874). The cardiovascular risk factors increased by LACI were age, BMI, diabetes, triglycerides, LA size, LASr, LASI, E/A, E/e’ and EF (p < 0.05). During a median follow-up of 16 months (range, 6–28 months), the event-free survival curves demonstrated a higher risk of heart failure in the group with LACI > 5.0 (log-rank test: P < 0.001). LACI > 5.0 was an independent predictor of heart failure [OR: 0.121, 95% CI (0.020–0.740), p = 0.022].

Conclusion

LACI may prove to be a valuable tool for assessing LA function in patients with CKD, and could be integrated into the routine assessment of LA for the purpose of prognostic assessment and clinical decision-making in patients with CKD.