bluuebunny/crossref_metadata_2025 huggingface dataset:
Early renal structural changes and potential biomarkers in diabetic nephropathy
Authors: Liu Hao , Feng Jianguo , Tang Liling
Published: November 2022

Diabetic nephropathy is one of the most serious microvascular complications of diabetes mellitus, with increasing prevalence and mortality. Currently, renal function is assessed clinically using albumin excretion rate and glomerular filtration rate. But before the appearance of micro-albumin, the glomerular structure has been severely damaged. Glomerular filtration rate based on serum creatinine is a certain underestimate of renal status. Early diagnosis of diabetic nephropathy has an important role in improving kidney function and delaying disease progression with drugs. There is an urgent need for biomarkers that can characterize the structural changes associated with the kidney. In this review, we focus on the early glomerular and tubular structural alterations, with a detailed description of the glomerular injury markers SMAD1 and Podocalyxin, and the tubular injury markers NGAL, Netrin-1, and L-FABP in the context of diabetic nephropathy. We have summarized the currently studied protein markers and performed bioprocess analysis. Also, a brief review of proteomic and scRNA-seq method in the search of diabetic nephropathy.
Dopaminergic nuclei in the chick midbrain express serotonin receptor subfamily genes
Authors: Fujita Toshiyuki , Aoki Naoya , Mori Chihiro , Serizawa Shouta , Kihara-Negishi Fumiko , Homma Koichi J. , Yamaguchi Shinji
Published: November 2022

Serotonin (5-hydroxytryptamine, 5-HT) is a phylogenetically conserved modulator of numerous aspects of neural functions. Serotonergic neurons in the dorsal and median raphe nucleus provide ascending innervation to the entire forebrain and midbrain. Another important neural modulatory system exists in the midbrain, the dopaminergic system, which is associated to reward processing and motivation control. Dopaminergic neurons are distributed and clustered in the brain, classically designated as groups A8–A16. Among them, groups A8–A10 associated with reward processing and motivation control are located in the midbrain and projected to the forebrain. Recently, midbrain dopaminergic neurons were shown to be innervated by serotonergic neurons and modulated by 5-HT, with the crosstalk between serotonergic and dopaminergic systems attracting increased attention. In birds, previous studies revealed that midbrain dopaminergic neurons are located in the A8-A10 homologous clusters. However, the detailed distribution of dopaminergic neurons and the crosstalk between serotonergic and dopaminergic systems in the bird are poorly understood. To improve the understanding of the regulation of the dopaminergic by the serotonergic system, we performed in situ hybridization in the chick brainstem. We prepared RNA probes for chick orthologues of dopaminergic neuron-related genes; tyrosine hydroxylase (TH) and dopa decarboxylase (DDC), noradrenaline related genes; noradrenaline transporter (NAT) and dopamine beta-hydroxylase (DBH), and serotonin receptor genes; 5-HTR1A, 5-HTR1B, 5-HTR1D, 5-HTR1E, 5-HTR1F, 5-HTR2A, 5-HTR2B, 5-HTR2C, 5-HTR3A, 5-HTR4, 5-HTR5A, and 5-HTR7. We confirmed that the expression of tyrosine hydroxylase (TH) and NAT was well matched in all chick dopaminergic nuclei examined. This supported that the compensation of the function of dopamine transporter (DAT) by NAT is a general property of avian dopaminergic neurons. Furthermore, we showed that 5-HTR1A and 5-HTR1B were expressed in midbrain dopaminergic nuclei, suggesting the serotonergic regulation of the dopaminergic system via these receptors in chicks. Our findings will help us understand the interactions between the dopaminergic and serotonergic systems in birds at the molecular level.
Upper arm versus forearm transcutaneous oximetry during upper limb abduction in patients with suspected thoracic outlet syndrome
Authors: Hersant Jeanne , Lecoq Simon , Ramondou Pierre , Feuilloy Mathieu , Abraham Pierre , Henni Samir
Published: November 2022

Context: Thoracic outlet syndrome (TOS) is common among athletes and should be considered as being of arterial origin only if patients have “clinical symptoms due to documented symptomatic ischemia.” We previously reported that upper limb ischemia can be documented with DROPm (minimal value of limb changes minus chest changes) from transcutaneous oximetry (TcpO2) in TOS.

Purpose: We aimed to test the hypothesised that forearm (F-) DROPm would better detect symptoms associated with arterial compression during abduction than upper arm (U-) DROPm, and that the thresholds would differ.

Methods: We studied 175 patients (retrospective analysis of a cross-sectional acquired database) with simultaneous F-TcpO2 and U-TcpO2 recordings on both upper limbs, and considered tests to be positive (CS+) when upper limb symptoms were associated with ipsilateral arterial compression on either ultrasound or angiography. We determined the threshold and diagnostic performance with a receiver operating characteristic (ROC) curve analysis and calculation of the area under the ROC curve (AUROC) for absolute resting TcpO2 and DROPm values to detect CS+. For all tests, a two-tailed p < 0.05 was considered indicative of statistical significance.

Results: In the 350 upper-limbs, while resting U-TcpO2 and resting F-TcpO2 were not predictive of CS + results, the AUROCs were 0.68 ± 0.03 vs. 0.69 ± 0.03 (both p < 0.01), with the thresholds being −7.5 vs. −14.5 mmHg for the detection of CS + results for U-DROPm vs. F-DROPm respectively.

Conclusion: In patients with suspected TOS, TcpO2 can be used for detecting upper limb arterial compression and/or symptoms during arm abduction, provided that different thresholds are used for U-DROPm and F-DROPm.

Clinical Trial Registration:ClinicalTrials.gov, identifier NCT04376177.
ER stress and calcium-dependent arrhythmias
Authors: Hamilton Shanna , Terentyev Dmitry
Published: November 2022

The sarcoplasmic reticulum (SR) plays the key role in cardiac function as the major source of Ca2+ that activates cardiomyocyte contractile machinery. Disturbances in finely-tuned SR Ca2+ release by SR Ca2+ channel ryanodine receptor (RyR2) and SR Ca2+ reuptake by SR Ca2+-ATPase (SERCa2a) not only impair contraction, but also contribute to cardiac arrhythmia trigger and reentry. Besides being the main Ca2+ storage organelle, SR in cardiomyocytes performs all the functions of endoplasmic reticulum (ER) in other cell types including protein synthesis, folding and degradation. In recent years ER stress has become recognized as an important contributing factor in many cardiac pathologies, including deadly ventricular arrhythmias. This brief review will therefore focus on ER stress mechanisms in the heart and how these changes can lead to pro-arrhythmic defects in SR Ca2+ handling machinery.
Pomelo seed oil: Natural insecticide against cowpea aphid
Authors: Ling Wei , Kaliaperumal Kumaravel , Huang Meiling , Liang Yan , Ouyang Zhigang , Zhou Zhonggao , Jiang Yueming , Zhang Jun
Published: November 2022

Cowpea aphid (Aphis craccivora Koch) is a plant pest that causes serious damage to vegetable crops. Extensive use of synthetic chemical pesticides causes deleterious effects on consumers as well as the environment. Hence, the search for environmentally friendly insecticides in the management of cowpea aphids is required. The present work aims to investigate the aphicidal activity of pomelo seed oil (PSO) on cowpea aphids, the possible insecticidal mechanisms, its chemical constituent profile, as well as the toxicity of its primary compounds. The results of the toxicity assay showed that PSO had significant insecticidal activity against aphids with a 72-hour LC50 value of 0.09 μg/aphid and 3.96 mg/mL in the contact and residual toxicity assay, respectively. The enzymatic activity of both glutathione S-transferase (GST) and acetyl cholinesterase (AChE) significantly decreased, as well as the total protein content, after PSO treatment, which suggested that the reduction of AChE, GST, and the total protein content in aphids treated with PSO might be responsible for the mortality of A. craccivora. The GC-MS analysis revealed that PSO contained limonene (22.86%), (9Z,12Z)-9,12-octadecadienoic acid (20.21%), n-hexadecanoic acid (15.79%), (2E,4E)-2,4-decadienal (12.40%), and (2E,4Z)-2,4-decadienal (7.77%) as its five major compounds. Furthermore, (9Z,12Z)-9,12-octadecadienoic acid showed higher toxicity to aphids than both PSO and thiamethoxam (positive control). This study emphasized the potential of PSO as a natural plant-derived insecticide in controlling cowpea aphids and also provided a novel approach for the value-added utilization of pomelo seed.
Knockdown of NtCPS2 promotes plant growth and reduces drought tolerance in Nicotiana tabacum
Authors: Xu Shixiao , Han Wenlong , Cao Kexin , Li Bo , Zheng Cong , Xie Ke , Li Wei , He Lingxiao
Published: November 2022

Drought stress is one of the primary environmental stress factors that gravely threaten crop growth, development, and yields. After drought stress, plants can regulate the content and proportion of various hormones to adjust their growth and development, and in some cases to minimize the adverse effects of drought stress. In our previous study, the tobacco cis-abienol synthesis gene (NtCPS2) was found to affect hormone synthesis in tobacco plants. Unfortunately, the role of NtCPS2 genes in the response to abiotic stress has not yet been investigated. Here, we present data supporting the role of NtCPS2 genes in drought stress and the possible underlying molecular mechanisms. NtCPS2 gene expression was induced by polyethylene glycol, high-temperature, and virus treatments. The results of subcellular localization showed that NtCPS2 was localized in the cell membrane. The NtCPS2-knockdown plants exhibited higher levels of gibberellin (GA) content and synthesis pathway genes expression but lower abscisic acid (ABA) content and synthesis pathway genes expression in response to drought stress. In addition, the transgenic tobacco lines showed higher leaf water loss and electrolyte loss, lower soluble protein and reactive oxygen species content (ROS), and lower antioxidant enzyme activity after drought treatment compared to wild type plants (WT). In summary, NtCPS2 positively regulates drought stress tolerance possibly by modulating the ratio of GA to ABA, which was confirmed by evidence of related phenotypic and physiological indicators. This study may provide evidence for the feedback regulation of hormone to abiotic and biotic stresses.
The mediating role of psychological commitment between recreation specialization and life satisfaction: Evidence from Xiamen Marathon runners
Authors: Tian Haibo , Zhou Wenting , Qiu Yajun
Published: November 2022

Although previous research spared no efforts to explain the life satisfaction of marathon runners, little was known about the relationship between recreation specialization (RS), life satisfaction (LS), psychological commitment (PC), and social support (SS). This study examines (i) how the dimension of RS (i.e., behavior, cognition, and affect) influences runners’ PC and LS, and (ii) the mediating effects of PC and the moderating effects of SS on the relationship between behavior, cognition, affect, and LS. The results showed that behavior (β = 0.15, p < 0.01), cognition (β = 0.35, p < 0.001), affect (β = 0.28, p < 0.001), and PC (β = 0.59, p < 0.001) had significant and positive impacts on runners’ LS; PC (Indirect path coefficient = 0.09 ~ 0.20) mediated the relationship between the dimensions of RS and LS. In addition, the results also confirmed the moderating effects of SS (β = 0.10, p < 0.05) between affect dimension and LS. These findings offered more evidence for understanding how RS dimensions and PC influence runners’ LS. Future research should integrate runner’s leisure experiences to better understand the results revealed in this study.
Frequency tagging with infants: The visual oddball paradigm
Authors: Peykarjou Stefanie
Published: November 2022

Combining frequency tagging with electroencephalography (EEG) provides excellent opportunities for developmental research and is increasingly employed as a powerful tool in cognitive neuroscience within the last decade. In particular, the visual oddball paradigm has been employed to elucidate face and object categorization and intermodal influences on visual perception. Still, EEG research with infants poses special challenges that require consideration and adaptations of analyses. These challenges include limits to attentional capacity, variation in looking times, and presence of artefacts in the EEG signal. Moreover, potential differences between age-groups must be carefully evaluated. This manuscript evaluates challenges theoretically and empirically by (1) a systematic review of frequency tagging studies employing the oddball paradigm and (2) combining and re-analyzing data from seven-month-old infants (N = 124, 59 females) collected in a categorization task with artifical, unfamiliar stimuli. Specifically, different criteria for sequence retention and selection of harmonics, the influence of bins considered for baseline correction and the relation between fast periodic visual stimulation (FPVS) responses and looking time are analyzed. Overall, evidence indicates that analysis decisions should be tailored based on age-group to optimally capture the observed signal. Recommendations for infant frequency tagging studies are developed to aid researchers in selecting appropriate stimulation and analysis strategies in future work.
Weight self-stigma and engagement among obese students in a physical education class
Authors: Zhang Bao Gen , Qian Xiao Fang
Published: November 2022

Background

This is a cross-sectional in design. It involves the mediating effects of basic psychological need satisfaction in relation to the moderating effects of teacher autonomy support regarding weight self-stigma's effect on engagement among obese students in physical education classes.

Methods

This study includes 165 Chinese high school obese students [mean age, 16.84 (±0.147) years], comprising 93 males (56.63%) and 72 females (43.63%), with a mean body mass index (BMI) of 30.453 (SD = 2.426). Participants completed the weight self-stigma questionnaire, basic psychological need satisfaction questionnaire, teacher autonomy support questionnaire, and student engagement questionnaire.

Results

Weight self-stigma and engagement among obese students were mediated by basic psychological need satisfaction. Moreover, the mediated effect of basic psychological need satisfaction was moderated by teacher autonomy support.

Conclusion

Weight self-stigma and basic psychological need satisfaction are the antecedents influencing the engagement of obese students. Notably, weight self-stigma not only directly blocks the engagement of obese students but also their engagement by hindering the acquisition of basic psychological need satisfaction. Teacher autonomy support can significantly reduce the negative impact of weight self-stigma on basic psychological need satisfaction and significantly promote engagement. Therefore, by promoting their physical education engagement, physical education teachers should strengthen the application of their supportive autonomous teaching strategies to help obese students meet their basic psychological needs.
A mediation model of the relationship between university students’ news media literacy and xenophobia: The role of intellectual humility, perceived threat, and blind patriotism
Authors: Lin Muyingnan , Chai Ching Sing , Liang Jyh-Chong
Published: November 2022

The dissemination of misinformation and disinformation has increased the need for news media literacy. This study administered a self-developed questionnaire to measure the relationship between news media literacy and xenophobia among college students in China (N = 430). The questionnaire measured five variables: news media literacy, xenophobia, blind patriotism, perceived threat, and intellectual humility. Confirmatory factor analysis (CFA) was used to validate this five-variable survey, and the analyses indicated satisfactory construct validity. Results from structural equation modeling indicated that intellectual humility was a significant predictor of news media literacy, and blind patriotism and perceived threat mediated the relationship between news media literacy and xenophobia. This study provides insights for researchers and instructors who are promoting news media literacy education in schools.
Draw yourself: How culture influences drawings by children between the ages of two and fifteen
Authors: Restoy Sophie , Martinet Lison , Sueur Cédric , Pelé Marie
Published: November 2022

The place children live strongly influence how they develop their behavior, this is also true for pictorial expression. This study is based on 958 self-portraits drawn by children aged 2–15 years old from 35 countries across 5 continents. A total of 13 variables were extracted of each drawing allowing us to investigate the differences of individuals and environment representations in these drawings. We used a principal component analysis to understand how drawing characteristics can be combined in pictorial concepts. We analyzed the effect of age, gender, socioeconomic, and cultural factors in terms of complexity and inclusion of social (human figures) and physical (element from Nature and man-made elements) environments, their frequencies, size, and proportions of these elements on each drawing. Our results confirm the existence of cultural variations and the influence of age on self-portrait patterns. We also observed an influence of physical and socio-cultural contexts through the level of urbanization and the degree of individualism of the countries, which have affected the complexity, content and representation of human figures in the drawings studied.
A cross-cultural investigation of people’s intuitive beliefs about the origins of cognition
Authors: Meng Xianwei , Wang Jinjing Jenny , Yoshikawa Yuichiro , Ishiguro Hiroshi , Itakura Shoji
Published: November 2022

Nature vs. nurture is an enduring theme of studies of the mind. Past studies on American children and adults have revealed a preference for thinking that even fundamental cognitive abilities documented in human infants and non-human species are late-emerging and reliant on learning and nurture. However, little is known about the generalizability of this “intuitive empiricist” belief and what factors may help explain it. Adult participants (N = 600) reported their beliefs about the emergence of several fundamental cognitive abilities demonstrated by preverbal infants. Studies 1A-1C showed that adults from both Japan and the US similarly estimated an older age of onset for cognitive abilities in human children as compared to the findings of cognitive science and consistently attributed acquisition of these abilities to learning rather than innateness in humans, and they made these learning attributions more so for humans than for non-human species. Study 2 showed that participants’ beliefs about biological evolution versus creationism were related to their age onset estimates for fundamental cognitive abilities, and their beliefs about the malleability of intelligence were related to participants’ explanations of the origin of fundamental cognitive abilities. These findings suggest generalizable preferences for nurture over nature across both Eastern and Western cultures (Japan and the United States), which may be related to people’s beliefs about human origins and the power of learning.
The impact of employees' pro-environmental behaviors on corporate green innovation performance: The mediating effect of green organizational identity
Authors: Cheng Zujie , Wu Banggang , Deng Xiaoyu , Li Wei
Published: November 2022

Employees' behaviors, as well as the employees' pro-environmental behaviors (PEB), affect the company in many dimensions. Although green innovation performance (GIP) has become an important measurement of a corporate's green development, research investigating PEB from the employees' perspective remains scarce, especially in emerging markets. Therefore, in this study, we developed an original framework to explore the effects of employees' PEB on corporate GIP and examined the underlying mechanism by conducting a survey in China. The results of the empirical analysis showed that employees' PEB increases corporate GIP by positively influencing green organizational identity (GOI). In addition, we also proved how leaders' PEB positively influences GIP, whereas innovation resistance (both technology resistance and resource resistance) has a negative effect on GIP. This study attempted to contribute to theoretical research and practical decision-making in the field of green organizational behavior.
Chains of tragedy: The impact of bullying victimization on mental health through mediating role of aggressive behavior and perceived social support
Authors: Guo Yi , Tan Xiao , Zhu Qiu-jin
Published: November 2022

Objective

Bullying is a worldwide concern for its devastating consequences. The current study focused on bullying victims, examining the effects of being bullied on mental health and the chain of mediating mechanisms among adolescents. Specifically, this study attempts to explain the relationship between bullying victimization and mental health from the perspective of maladaptive behavior and perceived social support.

Methods

A total of 3,635 adolescents responded to questions on bullying victimization, aggressive behavior, perceived social support, and mental health measurements including anxiety, depression, and subjective well being scale combined.

Results

(1) Bullying victimization was significantly correlated with aggressive behavior, perceived social support, and mental health, including anxiety, depression, and subjective well being. (2) Bullying victimization not only negatively predicts mental health levels but also has an indirect impact on mental health through three pathways: a separate mediating effect on aggressive behavior, a separate mediating effect on perceived social support, and a chain mediating effect on both.

Conclusion

The present results demonstrate that maladaptive behavior by bullying victims can lead to changes in their perceived social support and mental health problems. Violence begets violence and provides no constructive solutions, instead, produces a tragic chain of victimization. Further implications are discussed accordingly.
The influence of positive affect on sensitivity to important omissions
Authors: Mantel Susan P. , Montag-Smit Tamara , Kardes Frank R. , Barchetti Alberto
Published: November 2022

It is surprisingly difficult to notice when important information is missing (omission neglect) and yet, social media, advertisements, and other forms of communication typically only include one-sided information or positive attributes and omit opposing views or negative attributes. Even though it is surprisingly difficult to overcome this natural tendency, there are circumstances when decision makers are more sensitive to omissions. Understanding how and when decision makers can overcome this omission neglect tendency can be helpful to improve decision making in many situations. This paper investigates positive affect as a potential factor that can elicit sensitivity to omissions and alert decision makers to the need for additional information when important information is, in fact, missing. Four experiments use a consumer product choice situation to show that when decision makers are making an important decision, positive affect increases the likelihood that they will report a greater desire for additional product information (experiments 3 and 4) and temper their purchase interest in the target product. These results are shown using inference (experiments 1, 2, and 3) and by explicitly comparing a product choice with full and partial information (experiment 4). The results are discussed in terms of omission neglect literature as well as implications of the results for understanding the role of positive affect in information processing, judgment, and decision-making. These findings have implications for policy makers, marketers and others who are interested in message processing.
Knowledge, attitude, and its correlates of the community toward mental illness in Mattu, South West Ethiopia
Authors: Jarso Mohammedamin Hajure , Debele Gebiso Roba , Gezimu Wubishet , Nigatu Desalegn , Mohammedhussein Mustefa , Mamo Aman , Dule Aman , Hassen Mohammedjud , Jemal Kiyar
Published: November 2022

Background

The magnitude of mental health conditions in the general population was high in low-resource settings like Ethiopia. This was accompanied by little evidence on knowledge, attitudes, and related determinants in the general population. Therefore, the current survey is planned to assess the knowledge, attitude, and related factors of the community toward mental illness in Mattu, South West Ethiopia.

Objectives

Our study aimed to assess the knowledge, attitude, and related factors of the community toward mental illness in Mattu, South West Ethiopia.

Methods

A community-based cross-sectional survey was conducted in South West Ethiopia, Mattu town from 1 April−20 June, 2022 using a systematic random sampling, a multistage stratified technique from 649 households, and employed an interviewer-administered pre-tested semi-structured English version questionnaire. Epi-data Version 3.1 and SPSS-V-23.3 were employed for data entry and analysis respectively. A statistically significant association was declared at a P-value ≤ 0.05 at a 95% confidence interval.

Results

In the current study, poor knowledge regarding, and unfavorable attitudes toward, mental illness among study respondents were 28% (182) 95% CI (24.3, 31.6) and 60.4% (392) 95% CI (56.5, 64.3), respectively. After controlling for potential confounders, being self-employed was independently associated with poor knowledge [AOR = 3.1, 95%CI (1.65, 4.28)]. Moreover, current use of substances [AOR = 1.64 95%CI (1.09, 5.98)] and not hearing information about mental illness from social media have been shown to be associated in the final model with an unfavorable attitude [AOR = 3.44 95%CI (1.98, 5.99)].

Conclusion and recommendation

About one-third and more than one-half of the study participants showed poor knowledge and an unfavorable attitude, respectively. Compared to similar global and local findings, there was better community knowledge and a poor attitude toward mental illness in the area. Unfavorable attitudes toward mental illness were found to be exacerbated by participants not hearing about it on social media and by current substance use. Moreover, being self-employed was independently associated with poor knowledge of mental illness. Hence, all concerned stakeholders need to enhance mental health advocacy to improve public knowledge and attitude toward mental illness through media campaigns with a special focus on common substances. In addition, due attention should be given to self-employed groups of society to reduce the impacts of mental health conditions.
Comparison of pre- and intra-COVID-19 postpartum depression among reproductive aged women: A comparative cross-sectional study in Ahvaz, Iran
Authors: Afshari Poorandokht , Tadayon Mitra , Abedi Parvin , Beheshtinasab Maryam
Published: November 2022

Background

The association between PPD and COVID-19 pandemic has been studied in some countries. This study aimed to compare postpartum depression before and during the COVID-19 pandemic among reproductive-aged women in Ahvaz, Iran.

Methods

This comparative cross-sectional study involved 600 women of reproductive age in Ahvaz, Iran during the COVID-19 pandemic who were compared with 504 of their counterparts before the pandemic. Literate women who had given birth 1–6 months prior to the study, were aged 18–35, and were willing to participate in this study were recruited. A demographic questionnaire and Edinburgh Postnatal Depression Scale were used to collect the data. Independent t-test, Chi-square, and Logistic regression were used to analyze the data.

Results

Before the pandemic, only 123 (24.9%) of the women had PPD, while during the pandemic, this number rose to 409 (68.2%). During the COVID-19 pandemic, the women were 8.727 times more likely to have PPD (95% CI: 5.919–12.868). During the pandemic, women with high school education and those having a high school diploma were 2.454 and 2.054 times more likely to have PPD compared to women with a university degree (95% CI: 1.508–3.996 and 1.302–3.241, respectively).

Conclusion

The prevalence of PPD among Iranian reproductive-aged women increased during the COVID-19 pandemic. Policymakers should seek some strategies to support women during pregnancy and postpartum in times of crises such as the COVID-19 pandemic.
Status of work alienation among nurses in China: A systematic review
Authors: You Qian , Bai Dingxi , Wu Chenxi , Gao Jing , Hou Chaoming
Published: November 2022

Background

Work alienation is a common feeling of estrangement from the work and its context. Nurses are prone to feel alienated due to the high risk of infection, heavy workload, and the persistence of stress at high levels. Work alienation has serious negative outcomes, organizationally as well as personally. In recent years, the issue of work alienation among nurses has received considerable attention in China, but no systematic reviews have yet been published and its epidemiological status among Chinese nurses remains unclear.

Objective

To systematically evaluate the status and distribution characteristics of work alienation among nurses in China.

Methods

CINAHL, Embase, Web of Science, PubMed, CENTRAL, Wanfang, SinoMed, CNKI, and VIP were searched for cross-sectional studies before 10 January 2022 on the current status of work alienation among nurses. Two investigators independently screened the articles, extracted the data, and evaluated the risk of literature bias. Stata16.0 software was used for analysis.

Results

A total of 12 studies were included, with 7,265 nurses involved. Meta-analysis results showed that the score of work alienation was 35.43 [95%CI (31.82, 39.04)]. Subgroup analysis showed that the scores of male and female nurses were 37.62 and 35.79 respectively; the scores of junior, undergraduate, and graduate nurses were 34.90, 37.15, and 40.02 respectively; the scores of primary, intermediate, and senior nurses were 36.95, 35.38, and 33.11 respectively; the scores of unmarried and married nurses were 38.59 and 36.70 respectively; the scores of nurses who had worked for 1~ <6 years, 6~10 years, and more than 10 years were 37.46, 36.69, and 32.89 respectively; the scores of nurses with salary <5,000 yuan, 5,000~10,000 yuan, and more than 10,000 yuan were 40.25, 37.19 and 34.52 respectively; and the scores of nurses in emergency department and intensive care units, internal medicine, surgery, and pediatrics were 37.25, 38.73, 36.28, and 31.98 respectively.

Conclusion

Chinese nurses had a moderate level of work alienation. The scores of nurses in the following categories were quite high: male, higher education levels, low-professional titles, unmarried, shorter clinical working time, lower income, working in internal medicine, and working in the emergency department and intensive care units. Managers should take effective measures as soon as possible to reduce the occurrence of nurses' sense of work alienation.

Systematic review registration

https://www.crd.york.ac.uk/PROSPERO/, identifier CRD42022298746.
Association between maternal intimate partner violence and health-related quality of life in their preschool children: The mediating role of maternal parenting styles
Authors: Luo Shengyu , Lin Li , Chen Weiqing , Li Chunrong , Ren Yan , Zhang Meng , Guo Vivian Yawei
Published: November 2022

Background

Although intimate partner violence (IPV) against women is a public health issue around the world, there is a lack of evidence regarding the impact of maternal IPV on preschool children’s health-related quality of life (HRQOL). Therefore, the aim of this study was to investigate the association between maternal IPV and HRQOL among Chinese preschool children, as well as the mediating role of maternal parenting styles.

Methods

A cross-sectional study was conducted with 4,243 mother-child dyads who attended preschools. Mothers self-reported their parenting styles and experience of IPV. Children’s HRQOL was collected through mother-proxy report with the Pediatric Quality of Life Inventory version 4.0 (PedsQL 4.0). Multivariate linear regression analysis was conducted to evaluate the association between maternal IPV and children’s HRQOL. Mediation models were further applied to explore the possible mediating role of maternal parenting styles.

Results

Of the included mothers, 7.4% had experience of IPV. Compared to children of mothers without any IPV exposure, those of mothers with experience of IPV had significantly lower scores in all HRQOL dimensions and summary scales. After adjustment for covariates, maternal IPV was significantly associated with children’s lower physical health summary score, psychosocial health summary score, and total scale score. Mediation analysis showed that both rejection and overprotection mediated such associations, but not for the emotional warmth.

Conclusion

Our findings indicated the need to screen maternal IPV supplemented with targeted interventions focusing on parenting styles, in order to mitigate the negative impact of maternal IPV on children’s HRQOL.
Psychological impact on healthcare workers, general population and affected individuals of SARS and COVID-19: A systematic review and meta-analysis
Authors: Cheung Teris , Cheng Calvin Pak Wing , Fong Tommy Kwan Hin , Sharew Nigussie Tadesse , Anders Robert L. , Xiang Yu Tao , Lam Simon Ching ,   SR Nursing Working Group
Published: November 2022

Background

Any infectious disease outbreak may lead to a negative detrimental psychological impact on individuals and the community at large, however; there was no systematic review nor meta-analysis that examined the relationship between the psychological/mental health impact of SARS and COVID-19 outbreak in Asia.

Methods and design

A systematic search was conducted using PubMed, EMBASE, Medline, PsycINFO, and CINAHL databases from 1/1/2000 to 1/6/2020. In this systematic review and meta-analysis, we analyzed the psychological impact on confirmed/suspected cases, healthcare workers and the general public during the Severe Acute Respiratory Syndrome (SARS) outbreak and Coronavirus disease (COVID-19) epidemics. Primary outcomes included prevalence of depression, anxiety, stress, post-traumatic stress disorder, aggression, sleeping problems and psychological symptoms.

Result

Twenty-three eligible studies (N = 27,325) were included. Random effect model was used to analyze the data using STATA. Of these studies, 11 were related to the SARS outbreak and 12 related to COVID-19 outbreaks. The overall prevalence rate of anxiety during SARS and COVID-19 was 37.8% (95% CI: 21.1–54.5, P < 0.001, I2 = 96.9%) and 34.8% (95% CI: 29.1–40.4), respectively. For depression, the overall prevalence rate during SARS and COVID-19 was 30.9% (95% CI: 18.6–43.1, P < 0.001, I2 = 97.3%) and 32.4% (95% CI: 19.8–45.0, P < 0.001, I2 = 99.8%), respectively. The overall prevalence rate of stress was 9.4% (95% CI: −0.4 −19.2, P = 0.015, I2 = 83.3%) and 54.1% (95% CI: 35.7–72.6, P < 0.001, I2 = 98.8%) during SARS and COVID-19, respectively. The overall prevalence of PTSD was 15.1% (95% CI: 8.2–22.0, P < 0.001) during SARS epidemic, calculated by random-effects model (P < 0.05), with significant between-study heterogeneity (I2 = 93.5%).

Conclusion

The SARS and COVID-19 epidemics have brought about high levels of psychological distress to individuals. Psychological interventions and contingent digital mental health platform should be promptly established nationwide for continuous surveillance of the increasing prevalence of negative psychological symptoms. Health policymakers and mental health experts should jointly collaborate to provide timely, contingent mental health treatment and psychological support to those in need to reduce the global disease burden.

Systematic review registration

CRD42020182787, identifier PROSPER.
Prediction model of interaction anxiousness based on Weibo data
Authors: Wang Yilin , Zhao Nan
Published: November 2022

Adolescents who face social distress in real life are often accompanied by interaction anxiousness. To avoid direct social activities, they prefer to indulge in social networks to satisfy their psychological needs for interpersonal communication. Sina Weibo, China's leading social media platform, has a markedly young user base. It provides a rich sample of adolescents with interaction anxiousness and conditions for real-time monitoring. In this study, various word categories, such as perception of spatial distance and positional relationships, morality, and emotion, showed a significant relationship with interaction anxiousness. Furthermore, prediction models were established based on the original Weibo data of 839 active Sina Weibo users through a variety of machine learning algorithms to predict the scores of users' interaction anxiousness. The results showed that the performance of the prediction model established by the fully connected neural network was the best, and both criterion validity and split-half reliability were good (rcriterionvalidity = 0.30, rsplit − halfreliability = 0.76). This study confirms the validity of the prediction model of interaction anxiousness based on social media behavior data, provides a feasible solution to examine adolescents' interaction anxiousness, and provides a scientific basis for more targeted mental health interventions.
What produces and what controls the spatial-temporal structuring of the magnetospheric chorus waves that create the pulsating aurora: An unsolved problem in need of new measurements
Authors: Borovsky Joseph E. , Partamies Noora
Published: November 2022

In this Perspective article discussing solved and unsolved problems in space physics, the focus is on the unsolved problem of the spatial-temporal variability of the magnetospheric plasma waves that produce the spatial-temporal atmospheric luminosity of the pulsating aurora. In particular the outstanding issue of what causes the spatial-temporal variations of the chorus-wave intensities is highlighted: Two great unknowns are (1) how does it work and (2) what are the controlling factors. The point is made that the whistler-mode chorus waves that produce the pulsating aurora are the same chorus waves that energize the Earth’s electron radiation belt. Hence, beyond not understanding the cause of pulsating aurora there is (1) a lack of understanding of the magnetosphere-ionosphere system behavior and (2) a lack of understanding of how the electron radiation belt is energized. It is noted that the pulsating aurora is perhaps the most-obvious example of an “emergent phenomena” in the magnetosphere-ionosphere-thermosphere system, and so perhaps the clearest indication that the magnetosphere-ionosphere-thermosphere system is a truly “complex system”, not just a complicated system. Future needs for solving this unsolved problem are discussed: the most-critical need is argued to be gaining an ability to measure cold-electron structuring in the equatorial magnetosphere.
A participatory tool for assessing land footprint in city-region food systems—A case study from Metropolitan Copenhagen
Authors: Arciniegas Gustavo , Wascher Dirk , Eyre Poppy , Sylla Marta , Vicente-Vicente José Luis , Świa̧der Małgorzata , Unger Tina , Prag Adam A. , Lysák Marin , Schafer Luke J. , Welker Edith , Sanz Esther Sanz , Henriksen Christian B.
Published: November 2022

The ongoing COVID-19 pandemic has exposed the fragility of current food systems to feed populations around the world. Particularly in urban centers, consumers have been confronted with this vulnerability, highlighting reliance on just-in-time logistics, imports and distant primary production. Urban food demand, regional food supply, land use change, and transport strategies are considered key factors for reestablishing resilient landscapes as part of a sustainable food system. Improving the sustainability of food systems in such circumstances entails working on the interrelations between food supply and demand, rural and urban food commodity production sites, and groups of involved actors and consumers. Of special significance is the agricultural land in close proximity to urban centers. Calling for more holistic approaches in the sense of inclusiveness, food security, citizen involvement and ecological principles, this article describes the use of a new decision support tool, the Metropolitan Foodscape Planner (MFP). The MFP features up-to-date European datasets to assess the potential of current agricultural land use to provide food resources (with special attention to both plant- and animal-based products) and meet the demand of city dwellers, and help to empower citizens, innovators, companies, public authorities and other stakeholders of regional food systems to build a more regionalized food supply network. The tool was tested in the context of the food system of the Copenhagen City Region in two collaborative workshops, namely one workshop with stakeholders of the Copenhagen City Region representing food consultancies, local planning authorities and researchers, and one in-person workshop masterclass with MSc students from the University of Copenhagen. Workshop participants used the tool to learn about the impacts of the current food system at the regional and international level with regard to the demand-supply paradigm of city-regions. The ultimate goal was to develop a participatory mapping exercise and test three food system scenarios for a more regionalized and sustainable food system and, therefore, with increased resilience to crises. Results from this implementation also demonstrated the potential of the tool to identify food production sites at local level that are potentially able to feed the city region in a more sustainable, nutritious and way.
Involvement of women farmers in the agro-ecological transition and transformation of their work: Chronicle of the agricultural organization Groupe Femmes 44
Authors: Serpossian Emilie , Coquil Xavier , Annes Alexis
Published: November 2022

Women professional organizations appear as a resource for women to foster change in power relations on their farm. In this manuscript, we explore to what extent participation in a non-mixed professional organization named Groupe Femmes 44 contributed to transformations of women farmers' work. Particularly, we question the role of women farmers in the transition of their farming system toward agroecological principles and the conditions of their empowerment within their farm which allows these transitions. Our results show that Groupe Femmes 44 represents a socio-professional environment allowing women farmers to discuss, to put words and find answers on technical, communicational, organization as well as social issues. It allowed some participants to discover the existence, the relevance, and the more ecological dimension of self-sufficient and autonomous systems. Therefore, it stood as a key resource to foster professional transition toward these systems. For the women who were already involved in such systems, Groupe Femmes 44 contributes to the transition toward more equitable systems by questioning work organization and gender inequality.
Reconstruction of chronic radiation-induced ulcers in the chest wall using free and pedicle flaps
Authors: Zhou Bo , Long Ying , Li Sha , Lv Chunliu , Song Dajiang , Tang Yuanyuan , Yi Liang , Luo Zhenhua , Xiao Gaoming , Li Zan , Zhou Xiao
Published: November 2022

Background and purpose

Resection of radiation-induced ulcers often causes full-thickness defects of the chest wall. We retrospectively reviewed and evaluated 17 patients to explore a method of chest wall reconstruction.

Materials and methods

A total of 17 breast cancer patients with radiation-induced ulcers were included. Various type of prostheses and flaps were used, results of clinic were evaluated.

Results

Sixteen patients had full-thickness defects and one patient had only a soft tissue defect and underwent reconstruction with a pedicle latissimus dorsi (LD) myocutaneous flap. Among all 16 full-thickness defect cases, 15 patients underwent bony thoracic reconstruction using polymesh/3D-printed titanium plates or methyl methacrylate. For soft tissue reconstruction, 13 patients reconstruction using a free deep inferior epigastric perforator (DIEP) flap in combination with a contralateral transverse rectus abdominis myocutaneous (TRAM) flap, and 2 underwent pure free DIEP flap reconstruction. Among all the patients 15 healed with no complications, and 2 patients had delayed healing on the edges of the flaps.

Conclusions

Distant pedicle or free flap can used for soft tissue defect coverage, for those severe patients with full-thickness defects and used prostheses, free deep inferior epigastric perforator flap in combination with a contralateral transverse rectus abdominis myocutaneous flap (TRAM + DIEP) would be an applicable choice.
Olfactory enrichment using a maternal pheromone improved post-weaning pig performance and behavior
Authors: Archer Courtney , Garcia Arlene , Henderson Madelyn , McGlone John J.
Published: November 2022

The post-weaning environment in commercial pig nursery buildings is typically devoid of both the sow and her semiochemicals. Among other factors, the loss of maternal odors may contribute to post-weaning stress. In this work, we report four studies (studies 1-4) using 192 weaned pigs to evaluate the effects of a maternal pheromone (MP) containing Myristic Acid and Skatole on weaned pig behavior and performance. Study 1 examined behavior among weaned pigs with a focus on lying, aggression and feeding behaviors. All studies used body weight gain and the percentage of pigs that lost weight the first 7 days after weaning as key response variables. The MP stimulated early feeding behavior and reduced aggressive behaviors among weaned pigs (p<0.01). In study one, pigs were over 4 kg heavier 16 weeks post-weaning when the MP was present for 48 h post-weaning compared to control pigs (p=0.05). The three other studies used a 7-days bioassay to assess the best dose and form of delivery of the MP among weaned pigs. The single measure that responded uniformly was the percentage of pigs that lost body weight in the first 7 days after weaning. Among control pigs in four separate studies, 25% of the weaned pigs in each study lost body weight by 7 days after weaning, while in 3 of the 4 bioassay studies, 0% of MP-exposed pigs lost weight after weaning (one study had 6% of pigs losing body weight with the MP). This MP effect is both highly statistically significant and, if found on commercial farms, would have a large positive economic benefit. Simultaneously, having fewer pigs losing weight and exhibiting less aggressive behavior will improve the health and welfare of weaned pigs. Providing biologically-relevant olfactory enrichment can improve pig health and welfare.