bluuebunny/crossref_metadata_2025 huggingface dataset:
DEVELOPMENT AND VALIDATION OF RP-HPLC BASED ANALYTICAL METHOD FOR SIMULTANEOUS ESTIMATION OF MONTELUKAST AND BILASTINE IN TABLET DOSAGE FORM
Authors:   Technocrats Institute of Technology – Pharmacy, Bhopal, VYAS PRANAV , THAKUR VIVEK SINGH ,   Technocrats Institute of Technology – Pharmacy, Bhopal, BASEDIA DEEPAK ,   Technocrats Institute of Technology – Pharmacy, Bhopal, DUBEY BALKRISHNA ,   Technocrats Institute of Technology – Pharmacy, Bhopal
Published: April 2022

A new RP-HPLC method was developed for the estimation of bilastine and montelukast in tablets and it was validated as per ICH guidelines. The chromatogram for was found to be satisfactory on symmetry C-18 (4.6×150mm, 5µ Thermosil column) using phosphate buffer (pH 4.5) and acetonitrile in the ratio of 30:70 v/v at a flow rate of 0.8 ml/min. The retention time of montelukast and bilastine were found to be 7.03 min and 9.50 min respectively. The system suitability parameters proved that the proposed method is suitable for simultaneous estimation of bilastine and montelukast. Tailing factor for the peak was found to be 1.003 and 1.258 for montelukast and bilastine respectively and the theoretical plates for separation were found to be 3409 and 7365 respectively montelukast and bilastine. The method was found to be linear in the range of 10-50µg/ml for both the drugs. The precision of the method was good and the recovery of drugs is well within the acceptance limits of 80-120%. The LOD was found to be 0.003 µg/ml for montelukast and 0.09 µg/ml for bilastine while the LOQ ws found to be 0.012 µg/ml for montelukast and 0.3 µg/ml for bilastine. KEYWORDS: Montelukast, Bilastine, RP-HPLC, simultaneous estimation, validation, analytical method.
Piloting the CANRISK tool in Vancouver Coastal Health
Authors: Papineau D. , Fong M.
Published: April 2022

Introduction

Vancouver Coastal Health Authority’s Healthy Living Program implemented this pilot study to test and validate the Canadian Diabetes Risk Assessment Questionnaire (CANRISK) developed by the Public Health Agency of Canada as a screening tool for undiagnosed type 2 diabetes mellitus (DM) and prediabetes. Key objectives were to test the feasibility and acceptability of screening urban ethnic groups using the CANRISK, increase awareness of risk factors for DM and preDM and develop resources for lifestyle change.

Methods

The study recruited participants through community groups and churches, intraorganizational emails, primary care clinics and word of mouth. They completed the CANRISK and an oral glucose tolerance test (OGTT) either individually or as part of a group. Groups received a brief diabetes prevention information session. Documents to support lifestyle change were distributed to all participants.

Results

Participants (n = 556) were recruited among East Asian, Caucasian, South Asian and Latin American ethnic groups. Of these, 17% had OGTT results in the preDM range and 3% in the DM range. Over 90% of participants reported that the CANRISK wording was clear and that they had received useful information about lowering their diabetes risk.

Conclusion

The benefit of using an OGTT was in identifying 11% of the sample of participants who had impaired glucose tolerance (IGT) and did not show abnormal fasting plasma glucose (FPG) results. All participants with abnormal laboratory results were provided with follow-up educational interventions in their own language.
Study on the thermal properties of the grafted product of maleic anhydride onto clylized natural rubber by using thermogravimetric method
Authors:   Department of Agriculture Product Technology, Universitas Muhammadiyah Sumatera Utara, Medan 20226, Indonesia 2Agriculture Faculty, Universitas Al Azhar, Medan 20145, Indonesia, Siregar M. Said , Fitri Dian Arsita ,   Department of Agriculture Product Technology, Universitas Muhammadiyah Sumatera Utara, Medan 20226, Indonesia 2Agriculture Faculty, Universitas Al Azhar, Medan 20145, Indonesia, Nusa Muhammad Iqbal ,   Department of Agriculture Product Technology, Universitas Muhammadiyah Sumatera Utara, Medan 20226, Indonesia 2Agriculture Faculty, Universitas Al Azhar, Medan 20145, Indonesia, Ardilla Desi ,   Department of Agriculture Product Technology, Universitas Muhammadiyah Sumatera Utara, Medan 20226, Indonesia 2Agriculture Faculty, Universitas Al Azhar, Medan 20145, Indonesia, M.D Masyura ,   Department of Agriculture Product Technology, Universitas Muhammadiyah Sumatera Utara, Medan 20226, Indonesia 2Agriculture Faculty, Universitas Al Azhar, Medan 20145, Indonesia, Nasution Asmarasari ,   Agriculture Faculty, Universitas Al Azhar, Medan 20145, Indonesia, Eddiyanto Eddiyanto ,   Department of Chemistry, Universitas Negeri Medan, Medan 20221, Indonesia
Published: April 2022

This study aims to investigate the thermal properties of grafted products of maleic anhydride onto cyclized natural rubber. The grafting was carried out in the melt phase at an internal mixer of 150 oC and a rotor speed of 80 rpm. A total of 16 phr maleic anhydride was reacted with cyclized natural rubber in the present and absence of divinylbenzene comonomer with various mole ratios: 0.5, 1, and 2. The grafted products were characterized by the thermogravimetric method to investigate their thermal properties. Based on the results of the thermogravimetric analysis, it was shown that the sample increased its thermal stability. The sample decomposes at a higher temperature with the increasing mole ratio of divinylbenzene added. The grafted product with 16 phr maleic anhydride decomposed at 489.41 oC. Then, the graft product samples with the addition of 0.5, 1, and the 2-mole ratio of divinylbenzene comonomers decomposed at: 501.62 oC, 514.39 oC, and 520.82 oC, respectively.
Development of chemic media (chemistry comic) based on problem based learning on chemical bond materials for class x students
Authors:   Chemical Education Study Program, Faculty of Mathematics and Sains, Universitas Negeri Medan, Medan 20221, Indonesia, Nisa Selly Aprilia , Silaban Meli Sartika ,   Chemical Education Study Program, Faculty of Mathematics and Sains, Universitas Negeri Medan, Medan 20221, Indonesia, Silaban Saronom ,   Department of Chemistry, Universitas Negeri Medan, Medan 20221, Indonesia
Published: April 2022

This research is a development research that aims to determine the feasibility of chemic media based on problem based learning on chemical bonding material for class X students based on BSNP standards. In this research, a modified ADDIE development model was used where only the analysis, design, development and evaluation stages were carried out. This research will be conducted at the Department of Chemistry State University of Medan, SMAN 1 Secanggang and SMAS Bintang Langkat. The feasibility of the media is seen through a feasibility questionnaire based on the BSNP standard with a Likert scale of 1 to 5. The validity of the chemic media is obtained from the results of the validation of lecturers and teachers, while the respondents' assessment of chemic media is obtained from the results of the assessments of teachers, students, and students. The results obtained indicate that the chemical media developed is valid or feasible to use. This can be seen from the validation data in terms of content, presentation feasibility, language feasibility, graphic feasibility and problem based learning assessment, respectively, obtaining a percentage of 80.83%; 82.50%; 94.38%; 82.19% and 82.14% so that an average percentage of 82.00% is obtained which is included in the very high category. The results of respondents' assessments of chemic media were reviewed based on aspects of appearance, material and benefits which respectively obtained a percentage of 88.96%; 86.73%; and 86.67% with an average percentage of 87.6% which is included in the very high category.
Analysis of student scientific literacy using the socio-scientific issues (SSI) approach on reaction rate
Authors:   Chemistry Education Study Program, State Islamic University of Sultan Syarif Kasim Riau, Pekanbaru, Indonesia, Yani Juli , Afrianis Neti ,   Chemistry Education Study Program, State Islamic University of Sultan Syarif Kasim Riau, Pekanbaru, Indonesia
Published: April 2022

This research at analyzing and knowing student science literacy after using Socio-Scientific Issues (SSI) approach on Reaction Rate lesson at the eleventh grade of MIPA 1 of State Senior High School 4 North Tambusai, Rokan Hulu. This research was conducted in the first semester in the Academic Year of 2019/2020. It was quantitative descriptive research. A purposive sampling technique was used in this research, and the samples were 32 students. The instrument was an essay test and it was supported by an unstructured interview. The data obtained then were analyzed descriptively. The results of analyzing the data showed, based on the data of essay test results, mean percentages of scientific literacy indicators: implementing the appropriate knowledge was 66.01% (good), identifying was 69.21% (good), explaining the implications of scientific knowledge for society was 80.94% (good), proposing ways to investigate scientific questions was 54.68% (enough), and drawing the right conclusion was 75.78% (good). It could be concluded that the achievement of student scientific literacy skills on the aspects of science competencies of Reaction Rate lesson at the eleventh grade of MIPA 1 overall was on good category.
Development of e-module based on local wisdom to improve science literacy and reading literacy
Authors:   Chemistry Education Study Program, Postgraduate, Universitas Negeri Semarang, Semarang 50237, Indonesia, Setyorini Legian , Haryani Sri ,   Chemistry Education Study Program, Postgraduate, Universitas Negeri Semarang, Semarang 50237, Indonesia, Susilaningsih Endang ,   Chemistry Education Study Program, Postgraduate, Universitas Negeri Semarang, Semarang 50237, Indonesia
Published: April 2022

This research is motivated by (1) the results of reading literacy and science literacy in PISA, which is still low, and (2) technology and cultural-based learning media have not been developed by private high school chemistry teachers in Semarang. This research aims to develop a feasible E-module based on the local wisdom of spice drinks that can improve reading literacy and learners' science literacy. This research is a research and development with a 3-D model, which includes defining, designing, and developing. This study collects data through observation, questionnaires, and testing. The research instruments used are material expert validation sheets, multimedia expert validation, observation sheets, and instruments about reasoned multiple choice. The study subject was eight students of XI MIPA Kebon Dalem high school. Expert validation results of the material showed 92.85% (very valid). The validation results of media experts showed 85.71% (valid). E-modules are declared effective because there is an increase in the completion of learners' learning outcomes after using E-modules. E-Module based on local wisdom of spice drinks can visualize the factors that affect the rate of reaction material. So, it can be concluded that E-modules based on local wisdom spice drinks developed are worth using to improve learners' reading and science literacy.
Analysis of the needs of teachers and students on the inquiry-flipped classroom model in chemistry lessons
Authors:   Chemisrty Education Study Program, Postgraduate, Jambi University, Jambi 36361, Indonesia, Desmarani Suci , Rusdi Muhammad ,   Department of Chemistry Education, Jambi University, Jambi 36361, Indonesia, Haryanto Haryanto ,   Department of Chemistry Education, Jambi University, Jambi 36361, Indonesia, Triwahyudi Sugeng ,   Department of Chemistry Education, Jambi University, Jambi 36361, Indonesia
Published: April 2022

This study was conducted with the aim of looking at how the general description of student characteristics, material analysis, infrastructure, and problems in chemistry learning were used to support research on the use of inquiry based - flipped classroom E-LKPD in order to maximize the teacher's efforts to improve creative and self -thinking skills student efficacy. This research is a quantitative descriptive analysis research. data collection using interview and observation techniques. Interviews were conducted with teachers of chemistry subjects. The sample of students was taken by random sampling. The research subjects were 47 state high school students in Jambi City. The results showed that 78.7% of students had difficulty understanding chemistry lessons, and 61.7% of students had difficulty understanding chemical concepts, and 51.1% of students had difficulty understanding chemistry questions. The results of the study also said that 97.9% of students needed learning multimedia (e-LKPD). Based on the results of the study, it can be concluded that the inquiry-flipped Classroom model assisted by e-LKPD can be used as a solution to meet the needs of students and teachers, because this learning model is oriented towards student activity and uses technology in the learning process.
PENGARUH MODEL PEMBELAJARAN EXPLICIT INSTRUCTION TERHADAP HASIL BELAJAR COSTUME MADE PADA SISWA KELAS XI SMK NEGERI 3 TEBING TINGGI
Authors: . Nurhayati , Tampubolon Hotmaria , Maghfirah Nadya
Published: April 2022

Abtrak : Penelitian ini bertujuan untuk mengetahui pengaruh model Explicit Instruction terhadap hasil belajar pembuatan pola kebaya siswa kelas XI SMK Negeri 3 Tebing Tinggi. Teknik pengumpulan data untuk mengukur hasil belajar membuat pola kebaya dalam penelitian ini menggunakan lembar pengamatan pada hasil membuat pola kebaya. Teknik analisa data melalui uji normalitas, uji homogenitas, uji kecenderungan dan uji hipotesis menggunakan teknik analisa data uji-t. Hasil penelitian ini menunjukkan bahwa tingkat kecenderungan hasil belajar membuat pola kebaya menggunakan model pembelajaran Explicit Instruction pada siswa kelas XI Tata Busana SMK Negeri 3 Tebing Tinggi cenderung baik yaitu 82,35%. Dan tingkat kecenderungan hasil membuat pola kebaya tanpa menggunakan model pembelajaran Explicit Instruction cenderung cukup yaitu 52,94%. Hasil uji hipotesis dengan menggunakan uji-t diperoleh nilai thitung sebesar 8,38 dan ttabel  pada taraf signifikan 0,05 dk = 32  sebesar 1,7 . Dengan demikian thitung > ttabel (8,38 > 1,7 ). Oleh karena itu dapat disimpulkan bahwa terdapat Pengaruh Model Pembelajaran Explicit Instruction Terhadap Hasil Belajar Pembuatan Pola Kebaya Pada Siswa Kelas XI SMK Negeri 3 Tebing Tinggi.Kata Kunci : Model pembelajaran Explicit Instruction, membuat pola kebaya Abstract : The purpose of this research is to determine the effect of the Explicit Instruction model on learning outcomes of making kebaya patterns for class XI students of SMK Negeri 3 Tebing Tinggi. Data collection techniques to measure learning outcomes to make kebaya patterns in this study used observations on the results of making kebaya patterns. Techniques Data analysis through normality test, homogeneity test, trend test and hypothesis testing using t-test data analysis techniques. The results of this study indicate that the level of tendency of learning outcomes to make a kebaya pattern using the Explicit Instruction learning model in class XI Fashion Design students of SMK Negeri 3 Tebing Tinggi tends to be good, namely 82.35%. And the level of tendency of the results of making a kebaya pattern without using the Explicit Instruction learning model tends to be sufficient, namely 52.94%. The results of hypothesis testing using t-test obtained tcount value of 8.38 and ttable at a significant level of 0.05 dk = 32 of 1.7. Thus tcount > ttable (8.38 > 1.7 ). Therefore, it can be obtained that there is an effect of the Explicit Instruction Learning Model on Learning Outcomes of Making Kebaya Patterns in Class XI Students of SMK Negeri 3 Tebing Tinggi. Keywords: Explicit Instruction learning model, making kebaya pattern
PENERAPAN MODEL PENILAIAN BERBASIS TEKNOLOGI DIGITAL ASES UNTUK MENINGKATKAN AKTIFITAS BELAJAR MAHASISWA PADA MATAKULIAH KEBIJAKAN PUBLIK
Authors: Susilawati Evi , Khaira Imamul , . Atmawarni
Published: April 2022

Abstrak: Tujuan dari penelitian ini untuk mengetahui penerapan model penilaian berbasis teknologi digital ASES untuk meningkatkan aktifitas belajar mahasiswa pada mata kuliah Kebijakan Publik..Penelitian ini merupakan penelitian tindakan kelas dan dilakukan di 3 siklus, dimana setiap siklus terdiri dari beberapa tahapan, yaitu: perencanaan, pelaksanaan, tindakan, observasi, dan refleksi. Instrumen yang digunakan dalam penelitian ini adalah observasi dan tes lembar hasil observasi dosen dan mahasiswa.  Hasil penelitian menunjukkan bahwa penerapan model penilaian berbasis teknologi digital ASES  dapat meningkatkan aktifitas belajar mahasiswa pada mata kuliah Kebijakan Publik  yang dapat dilihat dari rata-rata nilai siklus 1, 2 dan 3  sebesar 67,40; 77,85; dan 83,05. Hasil belajar mahasiswa juga meningkat secara bertahap dari siklus pertama ke siklus ketiga, dimana nilai rata-rata siswa siklus 1, 2, dan 3 sebesar 60,40; 73,50; 81,86, masing-masingKata Kunci:Model ASES, Aktifitas Belajar, Mata Kuliah Kebijakan Publik Abstract: The purpose of this study is to determine the application of the ASES digital technology-based assessment model to improve student learning activities in the Public Policy course. This research is a classroom action research and is carried out in 3 cycles, where each cycle consists of several stages, namely: planning, implementing , action, observation, and reflection. The instruments used in this study were observations and test sheets from the observations of lecturers and students. The results showed that the application of the ASES digital technology-based assessment model could increase student learning activities in the Public Policy course which can be seen from the average value of cycles 1, 2 and 3 of 67.40; 77.85; and 83.05. Student learning outcomes also increased gradually from the first cycle to the third cycle, where the average value of students in cycles 1, 2, and 3 was 60.40; 73.50; 81.86, respectivelyKeywords: ASESModel, Learning Activities, Public Policy Courses
TRIANGULATION OF THE Cu-Sn-Se SYSTEM
Authors: Chorba O.J. , Filep M.J. , Pogodin A.I. , Malakhovska T.O. , Sabov M.Yu.
Published: April 2022

Copper-containing compounds exhibit a wide range of properties, including thermoelectric, photoelectric, optical magnetic, superionic, superconducting, etc., which determines the areas of their practical use. In recent years, studies of complex copper selenides as promising thermoelectric (TE) materials have been actively carried out due to their advantages over traditional TE materials. Like binary Cu2Se, ternary selenides have low phonon thermal conductivity and high electrical conductivity and thermoelectric quality factor. Typically, copper-containing compounds belong to the p-type conductors and crystallize in four main structural types, among which phases with a diamond-like structure should be distinguished. Data on the nature of physicochemical interaction in the Cu – Sn – Se system are limited and contradictory. In view of this, it is important to carry out the triangulation of the ternary system Cu–Sn–Se, which is the first stage of the study of multicomponent systems.
The investigated alloys of the Cu – Sn – Se system were obtained by fusing elementary components of high purity in vacuum quartz ampoules. The obtained alloys were investigated using X-ray powder diffraction (XRD) and differential thermal (DTA) analyzes. At the temperature of homogenizing annealing (170 ° С) there are seven binary Cu2Se, CuSe, CuSe2, Cu6Sn5, Cu3Sn, SnSe, SnSe2 and one ternary phase Cu2SnSe3 stable in the Cu – Sn – Se ternary system. The existence of the ternary phase of Cu2SnSe4 has not been confirmed, because the alloy corresponding to its stoichiometric composition is a mixture of Cu2SnSe3 and Se. To establish quasibinary sections of the Cu – Sn – Se system were performed the synthesis and phase analysis of only the significant points in the most informative areas. This ensures the establishment of the nature of the maximum number of quasibinary sections with a minimum number of syntheses. According to the results of phase analysis in combination with the literature data the triangulation of the Cu – Sn – Se system was carried out at 170 ° С. The quasibinarity of the Cu2Se – SnSe, Cu2Se – SnSe2, Cu2SnSe3 – Se, Cu2SnSe3 – SnSe, Cu6Sn5 – SnSe, Cu3Sn – SnSe, and Cu3Sn – Cu2Se sections was confirmed, and the quasibinarity of the Cu3Sn – Cu2Se was established at first.
Keywords: triangulation; quasibinary section; phase analysis.
COMPARISON OF FUNGICIDAL ACTIVITY OF FLUCONAZOLE AND FLUORINE-CONTAINING 1,2,4-TRIAZOLES VIA IN VITRO AND IN SILICO METHODS
Authors: Korol N. , Holovko-Kamoshenkova O. , Slivka M. , Tymoshchyk S. , Boyko N.
Published: April 2022

Diseases caused by fungal infections affect millions of people and plants every year. Candida albicans is one of the most common fungi, causing a variety of fungal diseases that are life-threatening, especially for cancer patients and HIV-positive people. At the same time, drug therapy aimed at treating these diseases is limited by the small number of drugs used. Among them, one of the most commonly used both in human treatment and as part of the active components of agricultural fungicides is fluconazole - a drug that combines the nucleus of 1,2,4-triazole and fluorine atoms.
Previously, we have investigated the antifungal activity of condensed salts of thiazolo[3,2-b][1,2,4]triazole obtained by electrophilic intramolecular cyclization, bis-triazoles and their alkylated derivatives, and proved the feasibility of their use as bactericides and fungicides.
The aim of this work is to investigate the interaction of fluconazole and synthesized fluorine-containing compounds of class 1,2,4-triazole with the enzyme "EC 2.2.1.6 Acetolactate synthase" in the crystal structure of Candida albicans and to evaluate the possible use of the obtained substances as fungicides.
In the current study, we investigated the antifungal action of fluorine-containing derivatives of 1,2,4-triazole-3-thione. Molecular docking was performed for the compounds with the highest fungicidal activity and the preparation of fluconazole for the enzyme "EC 2.2.1.6 Acetolactate synthase" Candida albicans. The results showed that one of the tested substances showed a higher affinity for binding in the active site of the enzyme than fluconazole. Therefore, the test substances are promising antifungal agents.
Keywords: 1,2,4-triazole-3-thione; fungicidal activity; molecular docking; Candida albicans.
EFFECTIVE SYNTHESIS OF 5-IODOMETHYL-2-PHENYLIMINOTHIAZOLIDINE
Authors: Povidaichyk M. , Onysko M.
Published: April 2022

Thioamides and thioureas are interesting building blocks for the synthesis of azaheterocycles with valuable biological properties. The electrophilic cyclization of N-alkenylthioamides and N-alkenylthioureas is one of the methods of their synthesis. It is known that halogen-induced cyclization of N-alkenylthioamides and thioureas leads to the annealing of 5- or 6-membered cycles. In particular, the cyclization of allylthioamides in the presence of halogen gives halomomethylthiazolines. N-allyl-N-arylthioureas react with halogens, arylselenyl chloride or aryl tert-trichloride to form thiazolidine rings.
The three-component reaction between unsaturated amine, isocyanate or isothiocyanate and halogen is the one of the methods for the synthesis of halogenated oxazolines or thiazolines. This reaction considered the using of propargyl amine, isocyanate and halogen, which leads to the formation of halomomethylidenoxazolidine or halomomethylidenethiazolidine. The formed vinyl halides are universal building blocks in organic synthesis due to their ability to modify. The aim of this work is to study the course of the three-component reaction between allylmethylamine, phenylisothiocyanate and iodine. The use of allylamine will allow to introduce a halogenomethyl group into the azaheterocycle, which will greatly facilitate its functionalization.
The reaction of equimolar amounts of phenylisothiocyanate, allylmethylamine and iodine was performed in acetonitrile. This led to an increase in the yield of the target reaction product. Increasing the reaction temperature from room to 50 ° C also increased the yield. The 5-iodomethyl-3-methyl-2-phenylimino-1,3-thiazolidine was isolated as a light brown oil after treatment of the reaction mixture with potassium carbonate. Obviously, the process of iodocyclization is preceded by the formation of N-allyl thiourea, which effectively enters into the electrophilic heterocyclization reaction with the participation of an additional nucleophilic center - a sulfur atom.
Thus, the resulting three-component reaction of phenylisothiocyanate, allylmethylamine and iodine is an effective method for the synthesis of bioperspective iodomethylthiazolidine, submitted for further functionalization.
Keywords: electrophilic cyclization; allylmethylamine, three-component reaction; iodomethylthiazolidine.
PREDICTING OF THE BIOLOGICAL ACTION OF S-ISOPENTENYL DERIVATIVES OF 1,2,4-TRIAZOL-3-THIONE
Authors: Korol N. , Holovko-Kamoshenkova O. , Slivka M. , Rusyn I. , Lendel V.
Published: April 2022

The 1,2,4-triazole heterocyclic system is widely known for its many applications, as the triazole core is part of pharmaceuticals, plant protection products and photoemulsions.
In previous studies, we have proved the valuable properties of derivatives of 1,2,4-triazole-3-thione nuclei, as well as their thioreters and condensed salts. The aim of this study is to conduct virtual screening and molecular docking of previously undescribed isopentenyl thioethers of 1,2,4-triazole, as well as to assess the ways of their further functionalization and feasibility.
In the current study, we investigated synthesis of isopentenyl thioethers of 1,2,4-triazole, predicted their biological activity, determined the joint antiviral activity, analyzed the interactions in the active site of human rhinovirus B14 and showed that the fluorine-containing thioether has the best structure in terms of virus activity. .
Keywords: 1,2,4-triazole-3-thione; antiviral activity; molecular docking; rhinovirus B14.
ЕCOLOGICAL STATE OF SOILS IN IRSHAVA AND KAMIANSKE UNITED TERRITORIAL COMMUNITIES
Authors: Symkanych O.I. , Salyuk М.R. , Delegan-Kokaiko S.V. , Glukh O.S. , Svatiuk N.I. , Chiypesh Y.V. , Petkanich А.М.
Published: April 2022

Soil is the main means of production in agriculture. One of the main dominant factors of transformation and deterioration of soils is human economic activity. The plowing of agricultural lands, depletion of soil cover, industrial pollution, excessive degradation are among them. Reducing the area of agricultural lands directly affects agriculture and leads to lower yields. It can cause an environmental and economic crisis, both in a particular region and in the country as a whole. Therefore, the study of the state of agricultural lands years is paid more and more attention and is an urgent task of researchers in recent.
The article is devoted to the study of the current ecological condition of soils in Irshava and Kamianske united territorial communities, Zakarpattia region. The assessment was performed on the following indicators: the content of humus, microelements (Zn, Pb), nitrogen, phosphorus, potassium, acidity, nitrates, nitrites. The obtained results showed that exceeding the maximum allowable concentrations in the selected soil samples for any of the elements (Zn, Pb) is not observed. The highest value of the eco-pollutants content was set for the Irshava city, especially for areas close to the road. In addition, it should also be taken into account that the intensive use of lands for agriculture with the introduction of mineral and traditional organic fertilizers in medium doses increases the level of heavy metals in soils. The studied soils have the low content of total lead: from 11.6 to 18.1 mg / kg. This value of Pb concentration in the samples is caused by the relationship between fixed forms of ecopolyutant and humus content. Humus content in studied areas equals 0,75 – 1,45% and corresponds to the low supply of soils with organic matter and the composition of soil-formed rocks.
The soils of these areas were found to have a medium acid pH of 4,6-5,04 and correspond to a low humus content, obviously due to the high level of the agricultural lands plowing and a decrease in the amount of the organic fertilizers. But in general, the soils of this farm are fit for growing fruit crops.
Keywords: soil, degradation; soil cover; soil fertility; degradation processes; soil protection; heavy metals; humus; soil quality deterioration; land protection.
Measuring Students' Perception on Mathematics Learning Using Fuzzy Conjoint Analysis
Authors: Kasim Zurina , Muhamad Sukri Nur Liyana
Published: April 2022

Mathematics courses are widely applied in the overall sector because mathematics is not only about the calculation or formulation, but also help in solving problems using mathematical modelling. Students need to have a good understanding of the theory of mathematics in order to produce the best results. In the world of digitization, subjects in science, technology, engineering and mathematics have become Malaysia’s agenda in the preparation to compete globally. Empowering in these subjects enable the creation of innovators of the future, hence create job opportunities in the digitization world. However, the academic institutions have been facing a critical problem in potential growth of achieving the mission and vision in enhancing the students’ performance when it is related to the students’ interest. This study focuses on students’ perception toward mathematics learning among 60 undergraduate management mathematics major’s students at UiTM Perlis using fuzzy set conjoint analysis. The attribute in each dimension is ranked according to the highest similarities values. The finding showed that students were rated neutral toward the preparation before class (student’s attitude); strongly agree that the lecturers are knowledgeable and well prepared before class (lecturer’s role); and rated neutral on female students are more qualified mathematician and their passion toward mathematics but strongly agreed that mathematics is difficult to understand in short period of time (student’s perspective).
CONSIDERACIONES EN TORNO A LOS BINOMIOS NOMINALES EN DOCUMENTOS DE LA AUDIENCIA DE QUITO DE LOS SIGLOS XVI Y XVII
Authors: CODITA Viorica
Published: April 2022

Considerations on Nominal Binomials in Documents of the Audience of Quito in the 16th and 17th Centuries. The phenomenon of binomials is very widespread in Spanish and is witnessed from its first texts. In the present work, the nominal binomial structures are analyzed in a corpus of documents of the Audiencia of Quito from the 16th and 17th centuries, since, in the history of the Spanish language, we are far from knowing the dynamics of the binomials in the American viceregal documentation. We will present some of the representative characteristics of the bimembre technique as a fact of writing the American documentation, insisting on its variational dimension.
Article history: Received 1 September 2021; Revised 20 October 2021; Accepted 11 November 2021; Available online 31 March 2022; Available print 31 March 2022.
REZUMAT. Consideraţii privind binoamele nominale în documente din Audiencia de Quito din secolele al XVI-lea şi al XVII-lea. Fenomenul binoamelor este răspândit în spaniolă și este atestat încă din primele texte. În studiul de faţă, sunt analizate structurile binomiale cu nucleu nominal într-un corpus de documente provenind de la Audiencia de Quito din secolele XVI și XVII, întrucât, în ceea ce priveşte istoria limbii spaniole, suntem departe de a cunoaște dinamica binoamelor în documentația viceregală americană. Vom prezenta câteva caracteristici reprezentative ale tehnicii bimembre ca fapt al redactării documentației americane, insistând asupra dimensiunii sale variaționale.
Cuvinte-cheie: binom, Audiencia de Quito, spaniola americană istorică, secolele al XVI-lea şi al XVII-lea
I TERMINI DI COLORE NELLE AREE BIANCO, NERO E GRIGIO NELLA STORIA DELL’ITALIANO
Authors: GROSSMANN Maria , D’ACHILLE Paolo
Published: April 2022

Colour Terms in the WHITE, BLACK and GRAY Areas in the History of the Italian Language. The present article is part of several studies that the authors have dedicated to the history of Italian colour terms. The Introduction illustrates some of the theses of Berlin, Kay (1969), with particular reference to the distinction between basic and non-basic terms. § 2 is dedicated to the Latin colour terms in the WHITE, BLACK and GRAY areas and their reflexes in the Romance languages. In § 3 the resources used for the research are presented. In §§ 3.1. (From Old Italian to the 19th century) and 3.2. (From the end of the 19th century to today’s Italian) the historical evolution and contemporary use of basic terms and other non-transparent colour terms are analyzed, also focusing on their figurative meanings and on the fixed collocations in which they occur. § 3.3. deals briefly with the terms formed by means of various morphological and syntactic devices that are most frequently used in Italian for the enrichment of the colour lexicon.
Article history: Received 26 July 2021; Revised 27 December 2021; Accepted 10 January 2022; Available online 31 March 2022; Available print 31 March 2022/
REZUMAT. Termenii de culoare în ariile ALB, NEGRU şi GRI în istoria limbii italiene. Articolul de faţă face parte dintr-o serie de studii pe care autorii le-au dedicat istoriei terminologiei cromatice în limba italiană. Introducerea ilustrează unele dintre tezele lui Berlin, Kay (1969), cu o deosebită atenție la distincția dintre termenii de bază și cei care nu au acest rol. § 2 este dedicat termenilor de culoare din ariile ALB, NEGRU și GRI în latină și reflexelor lor în limbile romanice. În § 3 sunt prezentate resursele utilizate pentru cercetare. În §§ 3.1. (De la italiana veche la secolul al XIX-lea) și 3.2. (De la sfârșitul secolului al XIX-lea până astăzi), sunt analizate evoluția istorică și folosirea contemporană a termenilor de bază și a altor termeni de culoare opaci, menționând și sensurile lor figurate și colocaţiile în care apar. § 3.3. tratează pe scurt termenii formați prin diferitele strategii morfologice și sintactice care sunt utilizate mai frecvent în italiană pentru îmbogățirea lexicului cromatic.
Cuvinte-cheie: semantică, formarea cuvintelor, termeni de culoare, italiană
QUELQUES CONSIDÉRATIONS SUR LA PLACE DU LATIN, AU REGARD DES AUTRES LANGUES EN CONTACT PRÉSENTES DANS "HRONICUL VECHIMEI A ROMANO-MOLDO-VLAHILOR" DE DIMITRIE CANTEMIR
Authors: VARIOT Estelle
Published: April 2022

Some Considerations on Latin Compared with Other Contact Languages, in Hronicul vechimei a romano-moldo-vlahilor by Dimitrie Cantemir. In this article, I propose to discuss some particularities of the language used by Dimitrie Cantemir in Hronicul vechimei a romano-moldo-vlahilor, taking into account the linguistic contacts in that era and the context of re-Latinization or re-Romanization of the Romanian language. To this end, I have consulted different editions of the Prince’s work to highlight convergences or differences in the presentation of language classes, and the way the author approaches the different languages with which he was in contact in his work.
Article history: Received 27 Mai 2021; Revised 16 September 2021; Accepted 12 October 2021; Available online 31 March 2022; Available print 31 March 2022.
REZUMAT. Câteva consideraţii asupra locului limbii latine din perspectiva celorlalte limbi în contact, prezente în Hronicul vechimei a romano-moldo-vlahilor al lui Dimitrie Cantemir. În acest articol, îmi propun să discut despre unele particularităţi ale limbii folosite de către Dimitrie Cantemir în Hronicul vechimei a romano-moldo-vlahilor, ţinând cont de contactele lingvistice din epoca respectivă şi de contextul de relatinizare sau de reromanizare a limbii române. În acest scop, am consultat diferite ediţii ale operei princepului evidenţiind unele convergenţe sau diferenţe în privinţa particularităţilor lingvistice ca, de altfel, şi modul în care autorul abordează diferitele limbi în contact în opera sa.
Cuvinte-cheie: lexic, limba română, subdialectul moldovean, hronicul, Dimitrie Cantemir, concordanţe romanice
Patočka frente a lo impolítico
Authors: Lucero Jorge Nicolás
Published: April 2022

Este trabajo analiza las cuestiones políticas del pensamiento de Jan Patočka a través de la perspectiva de lo impolítico, siguiendo especialmente la teorización que Roberto Esposito otorga sobre este enfoque. En primer lugar, se examina la figura de la persona espiritual como agente y defensor de una “política no-política”, quien aborda la problematicidad del sentido de forma comprometida con la comunidad y allende de cualquier interpretación místico-religiosa. En segundo lugar, se expone una afinidad entre los conceptos patočkianos de platonismo negativo, guerra y solidaridad de los conmovidos con el leitmotiv de lo impolítico. Se concluye defendiendo un sentido “impolítico” del Estado en la obra de Patočka a partir de su lectura sobre la fundación de la Primera Républica Checoslovaca.
Entre principio y método. Elementos para una comprensión fenomenológica de la durée bergsoniana
Authors: González Araneda Sergio
Published: April 2022

Se propone una lectura fenomenológica en torno al concepto bergsoniano de durée. Para esto, se revisa el registro y recepción de Bergson en la tradición fenomenológica. Al advertir la cercanía entre Bergson y la fenomenología, es analizable la durée fenomenológicamente. Es decir, la duración entendida como constitución de conciencia, de los objetos reales del mundo y de la relación entre la conciencia que aprehende y la experiencia aprehendida. Con ello, destaca el método de la intuición o simpatía intelectual en clave de método de división, a la vez, la posibilidad de conocimiento objetivo y esencial respecto de la realidad.
Comparison of Different Doses Botulinum Toxin Type a Efficacy in Chronic Anal Fissure Treatment
Authors: Goloktionov Nikolaj Aleksandrovich , Kashnikov Vladimir Nikolaevich , Tkalich Olga Vladimirovna , Ponomarenko Aleksej Alekseevich , Khryukin Roman Yurevich , Kostarev Ivan Vasilevich , Krstic Predrag , Slozhenikin Sergej Valerevich , Zagryadskiy Evgenij Alekseevich , Medvedev Vladimir Yurevich , Fomenko Oksana Yurevna , Nekhrikova Svetlana Viktorovna , Arslanbekova Karina Ibakovna , Misikov Viktor Kazbekovich , Akulov Mikhail Albertovich , Orlova Aleksandra Sergeevna , Zharkov Evgenij Evgenevich
Published: April 2022

Objective: To compare the results of chronic anal fissure treatment with 10 IU and 40 IU botulinum toxin type A.

Patients and methods: 56 patients were enrolled in case-control study divided into 2 groups consistent by the main clinical criteria. 28 patients in the study group had fissure excision in combination with 10 IU botulinum toxin type A (Xeomin) injection into internal anal sphincter, while 28 patients in control group received 40 IU product injections.

Results: No statistically significant results in the pain assessment during the day and after bowel movement were obtained (p=0.41 and p=0.93, respectively). The groups were comparable by the frequency of complications such as transient anal incontinence, perianal skin hematoma, acute urinary retention (p>0.05). Complications such as thrombosis of external hemorrhoids and chronic non-healing wounds were most common in the study group (p=0.43 and p=0.0005, respectively). The product dose increase to 40 IU has a more significant effect on the functional treatment results (p=0.0053 and p=0.0002, respectively) and increases the odds for postoperative wound epithelialization 15-fold (p=0.01). Conclusion: 40 IU Botulinum toxin type A shows improvement in the treatment of chronic anal fissure without any increased risk of postoperative complications.
Women in Mechanical Engineering: A case study of the Faculty of Engineering of the University of Porto in the last 20 years
Authors: Borges Catarina S. P. , Barbosa Ana Q. , Duarte Teresa P. , Lopes Helena S. , Jahanian Najafabadi Amir , Da Silva Lucas F. M.
Published: April 2022

Mechanical Engineering is often considered a course for men, however, during the past few years, the number of women enrolling and concluding the course is increasing, particularly in Portugal and at the Faculty of Engineering of the University of Porto (FEUP). The present study aims to analyse the female students that finished the Mechanical Engineering course at FEUP from 2001 to 2020, the motives behind their choice of the course and how being a woman has influenced, in their understanding, their path in this field.
Monstrous body: between alienness and ownness
Authors: Alichniewicz Anna
Published: April 2022

Monstrosity has its recognized place in cultural narratives but in philosophical discourse it remains mostly untouched. In my paper I make an attempt at phenomenological inquiry into the experience of the Other’s monstrous body. I am beginning with some remarks concerning Georges Canguilhem and Michel Foucault, the philosophers who devoted some attention to the problem of monstrosity and the monstrous, but my analysis is mainly based on the works of Bernhard Waldenfels, Edmund Husserl and Maurice Merleau-Ponty. Waldenfels emphasizes that the corporeal self is somehow perceived as alien, always somewhat distanced and not totally graspable. He also argues that the closer the Other, the stronger activation of the boundary between the spheres of the ownness and the alienness is caused. A promising framework for the analysis of the ambivalent reaction brought about by the encounter with a monstrous human body can be provided by Husserl’s phenomenological inquiry into the process of pairing, developed in his Cartesian meditations. It seems that in this experience the pairing process is frustrating and deranged because the process of apperception is disturbed by a cluster of untypical or quite unique characteristics of the monstrous body. In result, its sense remains unclear, puzzling and challenging. Interesting light on the experience of the Other’s monstrous body could shed Merleau-Ponty’s phenomenology, especially the ideas of flesh and chiasm outlined in his last work. The radical character of the monster, while does not render it something totally different from the own, elucidates, however, the contingency of the order under which the human corporeality is subsumed.
Legal interpretation in Paul Amselek’s phenomenology of law — between subjectivism and objectivism
Authors: Gołębiewska Maria
Published: April 2022

The aim of the article is to characterise and analyse Paul Amselek’s research approach to legal hermeneutics. The text provides an outline of Amselek’s assumptions and theses about legal interpretation, considered in the broad context of hermeneutics, and in the narrower context of legal logic and argument (including rhetoric and speech act theory). In point of fact, one of the methodological aims of Amselek’s philosophical reflection is to harmonise the two indicated contexts for framing interpretation — the wide context of hermeneutics, and the more narrow context of legal logic and argument. Amselek refers to issues in communication theory, reaching beyond the hermeneutic concept of text interpretation and evocation of the original authorial intention. He analyses the legal text-message in its content and argument layers, he also endeavours to specify the methodological possibilities of interpreting the attitudes and motivations of subjects — participants in communication situation (the sender and receiver of the message). He also inquires about the ethical attitudes of jurisdiction authorities, performing the interpretation of a body of law — the subjects responsible for lawmaking and the execution of law. Adopting post-Enlightenment anthropological assumptions, Amselek accepts the primacy of rationality in cognition, decision making, and activity of the human individual. However, in his considerations on interpretation he concurrently underscores the role of affective factors, motivating many choices and actions made by legal subjects.
Eko-/socjo-/polityka wrażliwości i gra symetrii (Władca Lewawu, Lustro pana Grymsa)
Authors:   Uniwersytet Pedagogiczny w Krakowie, Wądolny-Tatar Katarzyna
Published: April 2022

Eco-/socio-/politics of sensitivity and the game of symmetry (Lord of the Lewaw [Władca Lewawu], Mirror of Mr. Gryms [Lustro pana Grymsa]) The title of this article expresses the connectivity and even the inseparability of human ecological and sociological decisions and dependencies, indicating the filiation of these spheres. The “politics of sensitivity” translates into the level of social awareness of the relationship between the eco- and socio-planes. It builds the space of the effect (as it is also a reference to the publication by Michał Paweł Markowski, in which the researcher focuses on the existential turn in the humanities). On the other hand, the “game of symmetry” means striving for completeness, apogee, and harmony in a binary system. It is also a confrontational equation of forces, equalizing deficits resulting from neglect of the environment or human capital, which directs our attention towards the aspects of power and its mechanisms (according to literary studies, this element refers to the title of a sketch by Ireneusz Opacki, in which the Silesian scholar analyzes one of the positivist novels). In Mirror of Mr. Gryms [Lustro pana Grymsa] and Lord of the Lewaw [Władca Lewawu], Dorota Terakowska creates worlds with deficits and confronts the teenage protagonists with the need to eliminate them. The writer shows the relationship between the state of nature and the state of man and takes up the issues of power and its absolutization, perpetuating and magnifying the destruction in the internal and external world of the novel’s characters (in the individual and collective aspect). Both novels contain symmetrical constructive and compositional solutions. In addition, the twinness of the cities described in Lord of the Lewaw causes the symmetrization of the world presented in this novel. The writer also equalizes gender opportunities in terms of influencing the environment. The characters of the teenage heroes from both works, as constructs, are similar both characterologically and in terms of the course of their lives. Both also lose access to one of the lands and the ability to stay there. Agata (Mirror of Mr. Gryms) succumbs to amnesia caused by magicians, and the traces of her stay in another world are only found in fantastic paintings that she creates. The mirror ceases to exist. Bartek-Ketrab (Lord of the Lewaw) does not return to Krakow due to changes in the parameters of the transition between the worlds in which he exists. The heroes return to their families’ places. The changes that are made in the environments they have interfered with seem to be inevitable and positive. The structure of the novels also assumes a perceptive interiorization of the values and the important ecological and social ideas presented in them (sustainable management of natural resources, democracy, freedom).e