bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Pinching and Paclobutrazol on Growth, Flowering, Chemical Constituents, and Histological Features ofTecoma capensis(Thunb.) Lindl
Authors: Mohamed Y. F. Y. , Zewail Reda M. Y. , Sami Rokayya , Al-Mushhin Amina A. M. , Alyamani Amal , Aljahani Amani H. , El-Desouky Heba S.
Published: June 2022

This work aimed to evaluate pinching and paclobutrazol effects on pottedTecoma capensis(Thunb.) Lindl plant growth, flowering, and chemical composition. Assessed the growth, flowering, and chemical characteristics ofTecoma capensistransplants treated with and without pinching and paclobutrazol foliar spray (0, 75, 150, and 200 mg/l). Pinching and paclobutrazol treatments, and particularly the combined treatment of 200 mg/l paclobutrazol with pinching, reduced plant height and improved branch growth and root parameters. After 150 days, leaf midrib anatomy measurements increased significantly with the application of 200 mg/l paclobutrazol and pinching compared to the controls. The highest flower numbers, flower fresh and dry weight, and show value were achieved with the combination treatment of pinching and 200 mg/l paclobutrazoL. In addition, leaf nitrogen, Phosphorus, potassium, total carbohydrates, total chlorophyll, and leaf phenol contents were statistically increased by the interaction between pinching and 200 mg/l paclobutrazol. Moreover, applications of paclobutrazol at 150 mg/l with pinching and 200 mg/l without pinching significantly increased all aforementioned parameters. Pinching and paclobutrazol treatments were effective for achieving desired growth patterns inTecoma capensisplants, particularly with paclobutrazol concentrations of 200 mg/l.
Research on Mechanism of Doxorubicin Carried with Mesoporous Silica Nanoparticles Mesoporous Silica Nanoparticles in Regulating the Activity of Liver Tumor Cells Through Regulating the Activity of Hippo-Yes-Associated Protein Signal Pathway
Authors: Wang An , Jiang Jian-Shuai
Published: June 2022

This study assesses the mechanism of Doxorubicin (DOX) carried with Mesoporous Silica Nanoparticles (MSN) in regulating the activity of liver tumor cells through regulating the activity of Hippo-Yes-associated protein (Hippo-YAP) signal pathway. Adriamycin (ADM) was carried with nanoparticles
following preparation and HepG2 liver cancer cells were collected. The test for drug releasing in vitro was also performed. AMD ingestion was assessed using fluorescence microscope, while killing effect of drug in vitro was observed through CCK-8 method. The presentation activity
of Yes-associated protein (YAP) or p-YAP in liver tissue and liver cell line was detected through Western Blot assay, and real time-polymerase chain reaction (RT-PCR). Results showed that the ADM carried with nanoparticles was prepared successfully. The activity of stem cells was restrained
by DOX carried with nanoparticles, while presentation level of YAP was decreased. p-YAP level was increased while activity of liver cancer cells was restrained by DOX carried with MSN effectively. The activity of HippoYap signal pathway was affected and expression of YAP was restrained.
Anti-Liver Cancer Activity of Diaportheins Extracted fromPopulus lasiocarpaand Phylogenetic Analysis
Authors: Wan Xiao-Fang , Shi Huan , Zheng Ming-Juan
Published: June 2022

Liver cancer is a malignant tumor with poor prognosis but high incidence and mortality rates. To date, its emergence and development mechanism remains ambiguous. This malignancy is mainly treated through multidisciplinary comprehensive treatment. After the extraction and structural identification of diaportheins fromPopulus lasiocarpa, its anti-liver cancer activity was examined in this study. First, the suppression effect of diaportheins against the viability of liver cancer cells was detected using the Cell Counting Kit-8. The influence of the extract on the invasion and migration ability of the cancer cells was also determined by Transwell detection. Posture scoring software and molecular docking were employed to explore the possible binding models between the target proteins and the compound. Finally, the neighbor-joining phylogenetic tree of thePopulusspecies was also analyzed.
A Novel Core–Shell Structure TiO2Nanolayer Sphere Preparation and Electrocatalytic Degradation Study
Authors: Tang Si-Lu , Liu Ya-Lin , Li Xu-Ming , Chen Qian-Wen , Chen Heng-Yu , Zhou Ji-Li , Chen Liang , Gu Zi-Yi , Shao Shi-Xing , Qiao Pei-Zhi , Shen Guo-Dong , Yang Bing-Chuan
Published: June 2022

The core–shell TiO2nano-layer spheres were synthesized by hydrothermal method without surfactant, using tetraisopropyl titanate, diethylenetriamine and water as the capping agents. The structure of the products was characterized with X-ray diffraction (XRD), transmission electron microscope (TEM) and scanning electron microscopy (SEM). The possible formation mechanism and electrocatalytic degradation characters of the products were also discussed.
Science Applications of Phased Array Radars
Authors: Kollias Pavlos , Palmer Robert , Bodine David , Adachi Toru , Bluestein Howie , Cho John Y. N. , Griffin Casey , Houser Jana , Kirstetter Pierre. E. , Kumjian Matthew R. , Kurdzo James M. , Lee Wen Chau , Luke Edward P. , Nesbitt Steve , Oue Mariko , Shapiro Alan , Rowe Angela , Salazar Jorge , Tanamachi Robin , Tuftedal Kristofer S. , Wang Xuguang , Zrnić Dusan , Treserras Bernat Puigdomènech
Published: June 2022

Phased array radars (PARs) are a promising observing technology, at the cusp of being available to the broader meteorological community. PARs offer near-instantaneous sampling of the atmosphere with flexible beam forming, multifunctionality, and low operational and maintenance costs and without mechanical inertia limitations. These PAR features are transformative compared to those offered by our current reflector-based meteorological radars. The integration of PARs into meteorological research has the potential to revolutionize the way we observe the atmosphere. The rate of adoption of PARs in research will depend on many factors, including (i) the need to continue educating the scientific community on the full technical capabilities and trade-offs of PARs through an engaging dialogue with the science and engineering communities and (ii) the need to communicate the breadth of scientific bottlenecks that PARs can overcome in atmospheric measurements and the new research avenues that are now possible using PARs in concert with other measurement systems. The former is the subject of a companion article that focuses on PAR technology while the latter is the objective here.
The Creation of a Research Television Studio to Test Probabilistic Hazard Information with Broadcast Meteorologists in NOAA’s Hazardous Weather Testbed
Authors: Obermeier Holly B. , Berry Kodi L. , Klockow-McClain Kimberly E. , Campbell Adrian , Carithers Caroline , Gerard Alan , Trujillo-Falcón Joseph E.
Published: June 2022

Broadcast meteorologists play an essential role in communicating severe weather information from the National Weather Service to the public. Because of their importance, researchers incorporated broadcast meteorologists in the development of probabilistic hazard information (PHI) in NOAA’s Hazardous Weather Testbed. As part of Forecasting a Continuum of Environmental Threats (FACETs), PHI is meant to bring additional context to severe weather warnings through the inclusion of probability information. Since this information represents a shift in the current paradigm of solely deterministic NWS warnings, understanding end user needs is paramount to create usable and accessible products that result in their intended outcome to serve the public. This paper outlines the establishment of “K-Probabilistic Hazard Information Television” (KPHI-TV), a research infrastructure under the Hazardous Weather Testbed created to study broadcast meteorologists and PHI. A description of the design of KPHI-TV and methods used by researchers are presented, including displaced real-time cases and semistructured interviews. Researchers completed an analysis of the 2018 experiment, using a quantitative analysis of television coverage decisions with PHI, and a thematic analysis of semistructured interviews. Results indicate that no clear probabilistic decision thresholds for PHI emerged among the participants. Other themes arose, including the relationship between PHI and the warning polygon, and communication challenges. Overall, broadcast participants preferred a system that includes PHI over the warning polygon alone, but raised other concerns, suggesting iterative research in the design and implementation of PHI should continue.

Significance Statement

Broadcast meteorologists are the primary source of severe weather warning information for the U.S. public. As a result, researchers at NOAA’s National Severe Storms Laboratory and the Cooperative Institute for Mesoscale Meteorological Studies developed a mock television studio to allow broadcast meteorologists to use and communicate experimental products “on air” as part of the research-and-development process. Feedback provided by broadcasters is incorporated into products through an iterative process. Since 2016, 18 broadcasters have tested probabilistic hazard information at the warning time scale (0–1 h) for severe wind and hail, tornadoes, and lightning.
Rational and Moral Antecedents of Tourists’ Intention to Use Reusable Alternatives to Single-Use Plastics
Authors: Adam Issahaku
Published: June 2022

Though rational and moral antecedents to tourists’ pro-environmental behavioral intentions have been separately established, the literature remains inconclusive on whether tourists’ pro-environmental intentions are underpinned by rational or moral considerations. Based on the theory of planned behavior and the norm activation model, this study examines the competing rational and moral antecedents of intention to use reusable alternatives to single-use plastics using data obtained from 653 tourists and analyzed with the structural equation modeling. The results indicate that though morality better explained the intention to use reusable alternatives to single-use plastics amongst all tourists, rationality underpinned the intention amongst domestic tourists while morality better explained the intentions of international tourists. The implications of these findings regarding future theorization of tourists’ pro-environmental behavior and measures to reduce single-use plastic marine pollution in coastal destinations are discussed.
Mass drug administration for lymphatic filariasis elimination amidst COVID-19 pandemic in Odisha, India: A step towards achieving SDG-3
Authors: Sinha Abhinav , Mohapatra Sumegha , Mohanty Shubhashisha , Pati Sanghamitra , Sahoo Prakash Kumar
Published: June 2022

Sustainable Development Goal-3 (SDG) aims to eliminate lymphatic filariasis by 2030 through >65% coverage and compliance of mass drug administration (MDA), the preventive chemotherapy strategy of delivering anthelminthic drugs. However, the ongoing COVID-19 pandemic has disrupted such programmes, yet MDA was administered during February 2021 in Odisha, India. We aimed to assess the coverage and compliance of the present round of MDA amidst the pandemic and explore factors for non-compliance in Cuttack district of Odisha, a filariasis endemic area. Community-based participants enrolled through multistage stratified sampling were administered a semi-structured questionnaire following COVID-19 protocols. The coverage of MDA was 93.2% whereas consumption was 73.7%. Participants reported that healthcare workers were motivated and satisfactorily explained the benefits of MDA but still fear of side-effects was the major cause of non-compliance. Nonetheless, this recent round of MDA was effective, despite challenges posed by the ongoing pandemic.
What Makes Touch Comfortable? An Examination of Touch Giving and Receiving in Two Cultures
Authors: Schirmer Annett , Cham Clare , Zhao Zihao , Croy Ilona
Published: June 2022

This study examined how touch role and culture shape affective touch experiences. Germans ( N = 130) and Chinese ( N = 130) were surveyed once as toucher and once as touchee. For different touch actions, they (a) provided free-text descriptions of what prompts touch, (b) indicated with whom touch feels comfortable, and (c) highlighted areas of touch comfort on a body outline. Overall, touch was prompted by affectionate feelings, was more comfortable with more closely bonded individuals, and when directed at the upper arms, shoulders, and upper back. Touch role mattered for the experiences prompting touch in that touchees felt less positive than touchers. Culture differentiated touch comfort topographies. Compared with Chinese, Germans felt more comfortable with more intimate touch to the torso and upper back and less comfortable with more public touch to the hands. Notably, however, examining touch role and culture revealed more overlap than divergence, ensuring mutual comfort as individuals physically connect.
Lymphocytic myocarditis presenting as acute myocardial infarction: a case report and review of the literature
Authors: Huang Zhiwei , Feng Guangxun , Liang Yan
Published: June 2022

We report a case that presented as acute myocardial infarction (AMI) caused by lymphocytic myocarditis (LM), and explore the relationship between AMI and LM. We also performed a literature search to identify publications that previously reported LM-associated myocardial infarction. Coronary angiography of our patient revealed normal coronary arteries. However, a perfusion–metabolism mismatch in the apex and mid-inferior walls supported the diagnosis of AMI, and right ventricular septal endomyocardial biopsy showed LM. Extensive viral serological tests were negative for an infectious etiology. Immunosuppressive therapy may be beneficial in patients with high-risk myocarditis who are pathologically confirmed to be virus-negative.
Facing Adversity Together: Toward a Genre of Organization- Stakeholder Resilience Discourse
Authors: Anderson Lindsey B. , Jones-Bodie Ashley
Published: June 2022

Organizations, such as universities, face a variety of adversities, challenges, or disruptions that call for resilience to be enacted. Resilience is an important communicative process that relies on organizations and their stakeholders to collaboratively make sense of and respond to a given adversity, such as the COVID-19 pandemic. In order to identify the shared characteristics that organizations use in their communication surrounding adversity, we completed a genre analysis of the messages created by Big 10 Universities to welcome stakeholders to the 2020–2021 academic year. Through our analysis we uncovered commonalities that make organization-stakeholder resilience discourse distinct—(1) defining a shared relationship, (2) detailing steps to regain a sense of normalcy, and (3) describing the outcome of enacting resilience. Based on these findings, we propose a genre of organization-stakeholder resilience by highlighting the role of communication in cultivating resilience through the emphasis on discursive relationships that exist between organizations and stakeholders.
Effect of layering angles on shape memory properties of graphene oxide/carbon fiber hybrid reinforced composites prepared by vacuum infiltration hot pressing system
Authors: Xu Yi , Ma Yuqin , Wang Gangfeng , Xu Wei , Zhao Tingting , Li Fei , Guo Haiyin
Published: June 2022

Seven groups of different layering angles of Graphene oxide/Carbon fiber (GO-CF) hybrid reinforced shape memory composites are prepared by vacuum infiltration hot pressing system. The layering angles are respectively [0°]4, [±15°]s, [±30°]s, [±45°]s, [±60°]s, [±75°]s, and [90°]4. The shape fixation ratio, shape recovery ratio, and shape recovery driving force of GO-CF hybrid reinforced shape memory composites are investigated. The composite with the layering angle of [0°]4 has the minimum shape fixation ratio of 90.9%, the maximum shape recovery ratio of 97.6%, and the maximum recovery force of 2.83 N. Compared to [0°]4, the composite with the layering angle of [90°]4 has the 9.13% higher shape fixation ratio, but it has 16.1% lower shape recovery ratio and 59.4% lower recovery force. The microstructure of the composites is characterized and the microstructure of seven groups of composites is satisfactory. Therefore, the matrix within each group of composites has a similar effect on the shape memory properties of the composites. With the layering angle increased, the fiber resilience in the axial direction (X-direction) and the accumulated internal stress gradually decrease. With the layering angle increased, the shape fixation ratio and recovery time of GO-CF hybrid reinforced shape memory composites increase, while the shape recovery ratio, recovery force, and recovery rate decrease.
Psychological Well-Being in Childhood and Cardiometabolic Risk in Middle Adulthood: Findings From the 1958 British Birth Cohort
Authors: Boehm Julia K. , Qureshi Farah , Kubzansky Laura D.
Published: June 2022

Childhood adversity is linked to poor cardiometabolic outcomes, but less is known about positive childhood factors. Using data from 4,007 members of the 1958 British Birth Cohort, we investigated whether children with greater psychological well-being had lower adulthood cardiometabolic risk. At age 11, participants wrote essays about their future. Two judges rated each essay for nine psychological well-being items (Finn’s r = .82–.91), which were combined into a standardized overall score (Cronbach’s α = .91). When participants reached age 45, nurses assessed their blood pressure, heart rate, lipids, glycosylated hemoglobin, fibrinogen, and C-reactive protein, which were standardized and summed for total cardiometabolic risk. Regressions indicated that children with greater psychological well-being had lower cardiometabolic risk ( b = −0.14, 95% confidence interval [CI] = [−0.28, −0.006]): specifically, healthier total cholesterol ( b = −0.04, 95% CI = [−0.07, −0.003]) and triglycerides ( b = −0.06, 95% CI = [−0.09, −0.02]). Childhood psychological well-being may promote adulthood cardiometabolic health.
Strategic Entrepreneurship: A Review and Research Agenda
Authors: Ireland R. Duane , Withers Michael C. , Harrison Joseph S. , Boss David S. , Scoresby Richard
Published: June 2022

Strategic entrepreneurship integrates the fields of strategy and entrepreneurship to consider firms’ simultaneous engagement in opportunity- and advantage-seeking behaviors to create wealth. Since its conceptualization in the early 2000s, the study of SE has gained considerable momentum. At the same time, some scholars criticize SE and question its comprehensiveness as a way to understand the strategic application of entrepreneurship. We present a comprehensive review and integration of research related to the study of SE as a construct, theoretical model, and research domain. In doing this, we offer a research agenda across these different approaches to the study of SE.
Reconstruction of the Nose After Unilateral Cheilouranoplasty
Authors: Vissarionov Vladimir A. , Mustafaev Magomet Sh. , Mustafaeva Sofiyat M. , Karyakina Irina A. , Kuzhonov Dzhambulat T. , Mustafaev Muslim Sh.
Published: June 2022

Congenital clefts of the maxillofacial area still remain of current interest in reconstructive facial surgery. While their frequency grows up, the issues of effective surgical primary and secondary interventions are not completely solved yet. The article presents the main problems associated with the elimination of the deformations and our modifications of methods for their correction.

The study was conducted based on the Centre [2] and the University [1], Russian Federation. The project was carried out within the framework of the state assignment of the Ministry of Science and Higher Education of the Russian Federation, mnemocode 0669-2020-0008.

The research is based on the results of complex treatment of 112 patients with unilateral clefts of the upper lip and palate from the age of 5 to 34 years, 68 patients of them also carried out secondary surgeries.

The methods of performing rhinocheiloplasty by moving a “sliding” flap, of eliminating a ctenoid plica appearing after primary surgeries are presented, described, explained, and substantiated in the article.

The proposed methods gave a good or satisfactory result in 92.8% of the operated patients, which allows them to be considered effective for eliminating congenital and postoperative nasal deformities in patients with facial clefts.

: The surgical methods of eliminating congenital and postoperative deformities of the nose in patients with facial clefts should be modified in accordance with the nature of the most frequently arising shortcomings of the surgical stages of correction.
Glaucoma management in congenital ectropion uveae: Surgical outcomes from a large tertiary referral center in South India
Authors: Mandal Anil K , Gothwal Vijaya K
Published: June 2022

Purpose

To evaluate the long-term outcomes of glaucoma management in patients with congenital ectropion uveae (CEU) over a period of three decades at a single large referral tertiary eye care center.

Methods

Retrospective chart review of all patients with CEU treated surgically from 1990 to 2019 was performed. Primary combined trabeculotomy-trabeculectomy (CTT), trabeculectomy with and without mitomycin-C (MMC) (0.2 mg/mL for 1 min) and transscleral cyclophotocoagulation (TSCPC) were performed. Intraocular pressure (IOP) ≥6 and ≤16 mmHg without medications was considered as complete success and IOP≤ 16 mmHg with the use of upto 2 medications as qualified success.

Results

A total of 26 eyes of 21 patients were identified with a median age of 7 years (range, 6 days to 19 years) at the time of glaucoma surgery. Median follow-up was 51.1 months (range, 7–244.6 months). Primary CTT was performed in 17 eyes (65%), trabeculectomy in 5 eyes (19%) with application of MMC in 2 eyes, and 3 eyes (12%) underwent TSCPC. One painful blind eye (4%) underwent evisceration. Mean IOP reduced from 30.8 ± 7.6 mmHg on a mean of 1.3 ± 0.8 glaucoma medications preoperatively to a mean IOP of 15.2 ± 5.9 mmHg (P < 0.0001) on a mean of 0.2 ± 0.5 medications postoperatively at final follow-up (P = 0.0009). Complete success was achieved in 20 eyes, and qualified success in 2 eyes.

Conclusions

CTT is a safe and efficacious primary procedure for management of early-onset glaucoma in CEU. Trabeculectomy with or without adjuvant MMC is a viable second line of treatment in late-onset glaucoma with CEU for IOP control.
Association of Cardiac Arrest With Opioid Overdose in Transport
Authors: Ritter Marissa L , Bohr Adam D , McQueen Matthew B
Published: June 2022

Introduction:

Drug overdose is the leading cause of injury-related death in the United States. It has been linked to respiratory depression and cardiac toxicity, both of which can lead to cardiac arrest. Despite this potential association, few studies have examined this relationship, particularly in transport to the hospital. The purpose of this research was to determine if there was a relationship between opioid overdose and cardiac arrest in transport.

Methods:

A sample (n = 1 000 000) was utilized from the National EMS Information System (NEMSIS) from the year 2019. A logistic regression model was used to predict cardiac arrest from dispatch reason with gender, race, and age included as controls.

Results:

Overdose-related dispatch reason was associated with an increased likelihood of cardiac arrest in transport (Odds Ratio = 1.65, 95% Confidence Interval: [1.22, 2.22]).

Conclusions:

Opioid overdose is associated with an increased incidence of cardiac arrest in transport in the United States.
From media events to my events: Chinese mediated festivals in the digital era1
Authors: Feng Xian , Lu Isabel Fangyi
Published: June 2022

Much has been written about how digital technologies transformed contemporary festivals, yet the festival participants’ perceptions and experiences are less examined. Understanding mediated festivals as events of intertwined mediation processes, this paper explores the perception and practices of mediated festivals in contemporary China. We conducted semi-structured interviews with 13 Chinese young people to understand their motivations and experiences of festival participation. The paper finds that emerging mediated festivals provide a space for individuals to explore their interests. Further, mediated festivals are perceived as a liberating force for young people through choice-making and self-presentation in convivial and hybrid festival environments. Developing Dayan and Katz’s conception of ‘media events’, we argue that contemporary Chinese mediated festivals can be understood as ‘my events’ through hybrid and networked self-representations. Our study contributes to understanding the Chinese mediated festivals, emphasizing how networked individuals (re)negotiate the festival production.
Conceptualizing citizenship in dementia: A scoping review of the literature
Authors: O’Connor Deborah , Sakamoto Mariko , Seetharaman Kishore , Chaudhury Habib , Phinney Alison
Published: June 2022

Citizenship has provided an important conceptual framework in dementia research and practice over the past fifteen years. To date, there has been no attempt to synthesize the multiple perspectives that have arisen in this literature. The purpose of this paper is to explore, reflect on, and contrast, the key concepts and trends in the citizenship discourse as it relates to people with dementia. Using a scoping review methodology, forty-nine articles were identified for review. Despite the use of different descriptors, thematic analysis revealed four core themes underpinning citizenship discourse: 1) the relationality of citizenship; 2) facilitated agency and autonomy; 3) attention to stigma, discrimination and exclusion; and 4) recognition of the possibilities of identity and growth. Overall, this scoping review found a major emphasis on expanding definitions of agency and autonomy to render citizenship unconditional and inclusive of the diverse life experiences of people living with dementia. Notably, there is recognition that a more intersectional lens for embedding the subjective experience within a broader socio-political context is needed. Whilst the adoption of a citizenship lens in dementia research and practice has had real-world implications for policy and research, its exploration and use continue to be led by academics, highlighting the importance that future research involve input form people with dementia.
Plan Quality Comparison Between Hippocampus-Sparing Whole-Brain Radiotherapy Treated With Halcyon and Tomotherapy Intensity-Modulated Radiotherapy
Authors: Yokoyama Kazutoshi , Kurosaki Hiromasa , Oyoshi Hajime , Miura Kosei , Utsumi Nobuko
Published: June 2022

Objective: Hippocampus-sparing whole-brain radiotherapy using Halcyon, an instrument dedicated to volumetric modulated arc therapy, has not been studied till date; hence, we aimed to examine whether it can meet the RTOG0933 criteria. Based on this, we compared Halcyon to Tomotherapy, which also uses an O-ring-type linear accelerator. Methods: This exploratory, experimental, and retrospective study used 5 sets of computed tomography images in the head area to investigate the planning target volume, hippocampal doses, and irradiation time. Calculations were performed from 1 to 4 arcs to determine the optimal number of arcs in the Halcyon plan, which were compared to those of Tomotherapy. Results: The Radiation Therapy Oncology Group 0933 criteria could not be satisfied in Halcyon with 1 arc. With 2 arcs, the condition Dmax<16 Gy was not satisfied for 1 case in the hippocampus. Since there were no significant differences between 3 and 4 arcs, including the irradiation time, 3 arcs were considered the best. We compared Halcyon at 3 arcs with tomotherapy and found that tomotherapy was inferior to Halcyon at D98%; however, it was superior to Halcyon in other dose parameters. In contrast, the irradiation time in Halcyon was overwhelmingly superior, with the irradiation time for Halcyon being 1/ninth the time for Tomotherapy. Conclusion: Halcyon was effective in handling hippocampus-sparing whole-brain radiotherapy. We believe that 3-arc radiation is best suited for this procedure. Although Halcyon was inferior to Tomotherapy in terms of dose distribution excluding D98%, it was overwhelmingly superior in terms of irradiation time.
Effect of miR-196a2 rs11614913 Polymorphism on Cancer Susceptibility: Evidence From an Updated Meta-Analysis
Authors: Aziz Md. Abdul , Akter Tahmina , Islam Mohammad Safiqul
Published: June 2022

Background: MiR-196a2 rs11614913 polymorphism has been studied in a wide range of cancers throughout the years. Despite a large number of epidemiological studies performed in almost all ethnic populations, the contribution of this polymorphism to cancer risk is still inconclusive. Therefore, this updated meta-analysis was performed to estimate a meticulous correlation between miR-196a2 rs11614913 variant and cancer susceptibility. Methods: A systematic study search was carried out using PubMed, ScienceDirect, CNKI, EMBASE, Scopus, and Google Scholar databases following PRISMA guidelines to find necessary literature up to December 15, 2021. Pooled odds ratios with corresponding 95% confidence intervals were estimated using RevMan 5.4 based on ethnicities, cancer types, control sources, and genotyping methods. Results: A total of 152 studies, including 120 135 subjects (53 818 patients and 66 317 controls; 140 studies, after removing studies that deviated from HWE: 51 459 cases and 62 588 controls), were included in this meta-analysis. Quantitative synthesis suggests that the miR-196a2 rs11614913 genetic variant is significantly correlated with the reduced risk of overall cancer in CDM2, CDM3, RM, and AM (odds ratio < 1 and P < .05). It is also observed from ethnicity-based subgroup analysis that rs11614913 polymorphism is significantly ( P < .05) linked with cancer in the Asian (in CDM2, CDM3, RM, AM) and the African population (in CDM1, CDM3, ODM). Stratified analysis based on the cancer types demonstrated a significantly decreased correlation for breast, hepatocellular, lung, and gynecological cancer and an increased association for oral and renal cell cancer. Again, the control population-based subgroup analysis reported a strongly reduced correlation for HB population in CDM2, RM, and AM. A substantially decreased risk was also observed for other genotyping methods in multiple genetic models. Conclusions: MiR-196a2 rs11614913 variant is significantly correlated with overall cancer susceptibility. Besides, rs11614913 is correlated with cancer in Asians and Africans. It is also correlated with breast, gynecological, hepatocellular, lung, oral, and renal cell cancer.
Convolution neural network based particle filtering for remaining useful life prediction of rolling bearing
Authors: Liu Xiyang , Chen Guo , Cheng Zhenjie , Wei Xunkai , Wang Hao
Published: June 2022

Aiming at the problem of remaining useful life prediction of rolling bearing in aero engine, a data-driven prediction method based on deep learning and particle filter is proposed. Initially, only the vibration data of rolling bearing in normal stage are trained by the deep convolution neural network. According to the feature distance between normal and degraded samples, the evolution features during the whole lifetime are extracted adaptively, and the health index of rolling bearing is constructed. Then, the alarm and failure threshold are determined by unsupervised clustering algorithm. Combined with the extracted feature, remaining useful life of rolling bearing is tracked and predicted by particle filter algorithm based on four parameter exponential model. Finally, the effectiveness of the proposed method is verified by three groups of whole lifetime test data of rolling bearings. Results show that the degradation feature extracted by deep learning method has higher prediction accuracy of 2.19%, 0.93%, and 1.43% respectively than RMS values, and has more stable performance and less influenced by the number of particles or resampling methods, which can better reflect the evolution trend of rolling bearing than the traditional feature.
Synthesis and electrochemical properties of a nickel(II) thiacalix[4]arene-based electrocatalyst for the hydrogen evolution reaction
Authors: El Moll Hani , Alenezi Khalaf M , Haque Ashanul , Humaidi Jamal , Soury Raoudha , Azzam Eid MS , Abdulaziz Fahad , Latif Salman , Vraneš Milan
Published: June 2022

Thiacalix[4]arene with four sulfur-bridging atoms and four hydroxy coordinating groups in the lower rim is a promising candidate for powerful electrocatalytic hydrogen production. However, there are only a few examples reported in the literature where conjugated thiacalix[4]arene is used as a pre-catalyst for the hydrogen evolution reaction. The present work evaluates the electrocatalytic performance of a nickel(II) coordination complex based on generic thiacalix[4]arene. The coordination complex is characterized by cyclic voltammetry, where two reduction peaks are observed at −0.57 and −1.33 V for the two redox couples Ni2+/Ni+ and Ni+/Ni, respectively. The proton reduction occurs at the second peak potential with a slight shift at about −1.0 V, with increasing peak currents directly related to the number of acetic acid equivalents. The maximum peak current was observed to be at about 67 µA for 20 equiv. of acetic acid.
Clinical and financial impacts of flexible intramedullary nailing in pediatric diaphyseal forearm fractures: A case–control study
Authors: Leuba Aline , Ceroni Dimitri , Tabard-Fougère Anne , Lutz Nicolas
Published: June 2022

Purpose:

Flexible intramedullary nailing is regularly applied for pediatric displaced unstable forearm fractures. When compared to closed reduction and casting (orthopedic treatment), flexible intramedullary nailing decreases malalignment, shortens immobilization time, and should decrease follow-up controls. Comparing flexible intramedullary nailing and orthopedic treatment in the clinical, radiological, and financial managements of these fractures was performed.

Methods:

Retrospective 5 years study of pediatric cases in two pediatric orthopedic university departments. Treatment method, post-operative course, and radiological follow-up were reviewed. Number of radiographs, follow-up controls, type and duration of immobilization, final bone angulation, and reported complications were compared. Extensive financial analysis was completed.

Results:

Of 73 girls and 168 boys included in the study, 150 were treated by flexible intramedullary nailing and 91 by orthopedic treatment. No difference was noted with regard to total number of radiographs (7.3 vs 7.2, respectively). Total number of follow-ups was 6.4 and 5.5, respectively. Malalignment occurred in two flexible intramedullary nailing and sixteen orthopedic treatments. The least expensive cost was ambulatory orthopedic treatment.

Conclusion:

Flexible intramedullary nailing treated children had similar numbers of radiographs or follow-up consultation, but less malunion when compared to orthopedic treatment. Orthopedic management was systematically cheaper than flexible intramedullary nailing. Unless post-operative management guidelines decreasing the number of radiographs and follow-ups are implemented, flexible intramedullary nailing will remain a costly procedure when compared to conventional orthopedic treatment.

Level of evidence:

level III case–control retrospective study.
Insulin Pump-Associated Adverse Events in a Brazilian Reference Center for the Treatment of Diabetes Mellitus: Proposal for a Taxonomy of Device Failures in Adults, Adolescents, and Children
Authors: Neves Ana Lúcia Domingues , Martins Luiz Eduardo Galvão , Gabbay Mônica Andrade Lima , Cavicchioli Gabriela , Tenorio Fernanda Silva , Cunha Tatiana Sousa
Published: June 2022

Background:

Since the introduction of continuous subcutaneous insulin infusion (CSII), the benefits have been numerous. However, adverse events (AEs) are experienced by up to 40% of users per year, exposing them to potentially fatal risks. The available evidence on the variables that trigger AEs associated with CSII remains limited, indicating the importance of studies on the subject.

Aim:

To propose a taxonomy based on the prevalent AEs experienced by patients from a reference diabetes mellitus (DM) center in Brazil using different CSII devices.

Methods:

118 patients participated in an online interview and answered the questions of the data collection instrument. Identifying categories and subcategories of analysis contributed to constructing the AEs taxonomy.

Results:

The five analysis categories identified were: CSII User Interface (n = 45), CSII Alert System (n = 13), CSII Software and Connection (n = 11), CSII Durability (n = 30), and Electrical and Mechanical System of CSII (n = 60) A total of 159 AEs were identified, including conflicting alert messages and error/warning notification failures, errors resulting from engine malfunctions, data loss, patient interface deficiencies, button problems, and battery failure.

Conclusions:

The study describes in a taxonomic format the AEs directly associated with the use of modern CSIIs that may contribute with additional information to the Food and Drug Administration (FDA) Medical Device Report (MDR) adverse event codes. In addition to guiding educational actions in the treatment of DM and providing information for health professionals and medical device developers, prospective studies examining the frequency of such problems, including the potential psychosocial impact of this technologically advanced therapy, are needed.
Nasal Spine of the Frontal Bone: A Consistent Landmark for Safe Outside-In Frontal Drill-Out
Authors: Tawfik Ali , Abd El-Fattah Ahmed Musaad , El-Sisi Hossam , kamal Elsharawy , Ebada Hisham Atef
Published: June 2022

Background

Outside-in frontal drill out entails drilling the frontal sinus floor in the midline before identifying and dissecting the frontal recesses. It is a more direct approach, especially in revision surgery or cases with challenging anatomy.

Objectives

The aim of this study was to highlight the anatomical and surgical concepts for easy and safe outside-in frontal drill out by a preclinical anatomic study on cadaveric heads. In addition, to review our experience with this approach over a 5-year period for challenging frontal sinus pathologies.

Methods

The study included 2 sectors; a preclinical study, in which 5 cadaveric heads were dissected and studied to identify and standardize the anatomical landmarks of this approach. This was followed by a clinical case series which included 22 patients with challenging frontal sinus pathologies that were treated with this proposed approach.

Results

We concluded from the anatomic study that the nasal spine of the frontal bone (NSFB) and its anatomical orientation in relation to the nasal branch of the anterior ethmoidal artery (NBAEA) is a consistent landmark that enables the surgeon to identify the correct coronal trajectory of drilling to avoid injury of the cribriform and the skull base. The clinical case series included 22 patients that were successfully treated with the proposed approach. No intraoperative nor postoperative complications were reported in this study. Long-term follow-up showed that the frontal neo-ostium was patent in all cases (n  =  22).

Conclusion

Outside-in frontal drill-out is a safe and easy approach; especially in challenging frontal sinus pathologies; using the NSFB and its anatomical coronal orientation to the NBAEA as a consistent landmark, anterior to the skull base. This approach offers early, safe, and direct bone removal without the need for initial identification and dissection of the frontal recess.
A case report of lymphedema as an unusual initial presentation of breast carcinoma
Authors: Ng Yam Hock , Ibrahim Saadon , Chai Yee Chin
Published: June 2022

Breast carcinoma is one of the most common carcinomas among women around the world. Most of the women with breast carcinoma will present with signs and symptoms of breast problems to the health facility. Upper limb swelling is one of the rare initial presentations although it is rather common in patients as a sequelae of breast carcinoma treatment. We herein would like to report a case where a post-menopausal female presented with left upper limb swelling with initial history suggestive of traumatic injury of biceps muscle. Subsequent investigations of ultrasound, mammography, biopsy sample of the left breast found that the left upper limb swelling was due to a newly diagnosed invasive lobular carcinoma of the breast, staging of cT4cN2Mx which caused a rapidly progressing stage 2 lymphedema of the left upper limb. Lymphedema of the upper limb is a common complication of breast carcinoma treatment, especially those who require axillary lymph nodes clearance. Breast carcinoma with initial presentation of lymphedema of the upper limb is rare. Due to the rare presentation, diagnosis of breast carcinoma can be delayed. Clinicians should have high awareness to exclude breast cancer when a patient presents with unilateral upper limb swelling.
Poly(butylene succinate-co-adipate)/poly(hydroxybutyrate) blend films and their thermal, mechanical and gas barrier properties
Authors: Luoma Enni , Rokkonen Teijo , Tribot Amélie , Nättinen Kalle , Lahtinen Jussi
Published: June 2022

Depleting fossil resources and plastic pollution have generated an increasing demand for development of renewable and biodegradable polymers. Among other applications, packaging films are at the forefront of the scene. Poly(butylene succinate-co-adipate) (PBSA) is an interesting biopolymer due to its flexibility and good processability. However, its poor barrier properties limit the range of applications. On the contrary, poly(hydroxybutyrate) (PHB) biopolymer reveals good barrier performance, as well as stiffness and fast biodegradation rate. However, PHB drawbacks are its brittleness and difficult processability. By physical blending approach, a solution was delivered to overcome the shortcomings of these biopolymers, resulting in tailored properties of the films. PHB improved barrier performance of the blend film while flexible PBSA contributed to easier processability and better ductility. In this study, biobased and biodegradable blend films were produced in pilot-scale. The effects of PBSA/PHB blending were extensively studied by tensile testing, water and oxygen barrier testing, and thermal analysis. PBSA/PHB blend films exhibited improved Young’s modulus in comparison to neat PBSA. With 50 wt% PHB content, modulus of blend film was increased by 554% compared to pure PBSA film. The ductility of blend films decreased as a function of PHB content, becoming completely brittle at 50 wt%. It was found that barrier properties of PBSA/PHB films improved in comparison to neat PBSA. Oxygen transmission test results showed that oxygen permeability decreased as a function of PHB content. Similar trend was observed with water vapour permeation properties.
“The Shade of It All”: How Black Women Use Instagram and YouTube to Contest Colorism in the Beauty Industry
Authors: Childs Kiara M.
Published: June 2022

This article examines the affordances of Instagram and YouTube in leveraging Black women the ability to contest antiblackness and colorism in the beauty industry. Specifically, I examine how prominent Black beauty influencers, Jackie Aina and Nyma Tang, and everyday Black women respond to the cosmetic brand, Beautyblender, and their lack of foundation shades in the initial release of their first foundation. Using Critical technocultural discourse analysis (CTDA), I explore the importance of Black women’s content creation and call-out practices within racist beauty culture. I argue that Instagram and YouTube afford Black women the ability to contest antiblackness and colorism in the beauty industry and practice traditional Black feminist traditions such as self-definition and self-empowerment. Overall, I illuminate how Instagram and YouTube became sites of contention between brands, users, influencers, to engage in discourse about the political economy and material culture of Black beauty.
Sustenance of Food Security Through Natural Resources and Traditional Weekly Markets during COVID-19 Pandemic: A Study on the Tribal Villages of Karbi Anglong District of Assam
Authors: Bhattacharjee Somenath
Published: June 2022

Karbi Anglong district of Assam is a zone of diversified natural resources and multicultural tradition. The present article highlights their traditional weekly markets or Hats (which is locally termed as Hithi), organised and participated by the Karbi tribal people as well as their traditional number system and practices of barter system. Such markets are either conducted weekly or fortnightly. Primary data related to the present study has been collected through field works with the help of anthropological methods. The prime objective of the present study is to find out how indigenous knowledge, locally available natural resources and traditional economic organisations have collectively sustained the daily livelihood of the marginal areas, through the traditional markets as well as through the age-old barter system, under the acute threat of COVID-19 pandemic.

It has been found that such traditional markets are the platform for the Karbi people of the rural areas, to channelise their local production and to generate a scope of earning for themselves under the lockdown phases of COVID-19 pandemic.
Husband’s involvement in wife’s antenatal care visits in Indonesia: What factors are related?
Authors: Laksono Agung Dwi , Wulandari Ratna Dwi , Widya Sukoco Noor Edi , Suharmiati Suharmiati
Published: June 2022

Background:

Involving husbands in maternal and child health programs can reduce maternal morbidity and mortality. The study aimed to analyze the factors related to the husband’s involvement in antenatal care (ANC) visits in Indonesia.

Methods:

The study was a cross-sectional study. The research employed secondary data from the 2017 Indonesian Demographic and Health Survey. The analysis units were wives aged 15–49 years old, married, and pregnant in the past 5 years, and the final samples obtained were 14,319 respondents. In addition to the husband’s involvement were residence, age, education, occupation, wealth, and parity. The study used a binary logistic regression test in the final stage.

Results:

Husbands who lived in urban areas have odds of being involved in ANC visits 1.2 times greater than those in rural areas. The better the husband’s education was, the more involved they were in ANC. The results show husbands who work in any field were better at being involved in ANC. Poorer husbands had odds of being engaged in ANC visits 2.0 times more likely than the husbands’ lowest group. The most prosperous husbands have odds of being involved in ANC visits 5.4 times than the poorest husbands. The husbands’ wealth is better, the more the husbands were engaged in ANC. The more children were born, the less frequent the husbands’ involvement in ANC is.

Conclusion:

The study concluded five variables associated with husbands’ participation in ANC in Indonesia, including residence, education, occupation, wealth, and parity.