bluuebunny/crossref_metadata_2025 huggingface dataset:
Functional Outcome of Inter-Trochanteric and Sub-Trochanteric Fracture Femur Treated with Proximal Femur Nail Antirotation-II
Authors: Avate Shivaji , L. Gaonkar Kiran , Vatsa Madhuranjan , Lipi Kumari , Patil Sudhir
Published: February 2024

Intertrochanteric femoral fractures are of great interest all around the world. They are the most often performed fracture type, and the high expense of treatment required following injury has made them a critical health resource concern. A higher predisposition towards Intertrochanteric fracture is observed in females than males due to osteoporosis A substantial demand is placed on the implanted hardware, as the subtrochanteric region of the femur experiences mechanical forces several multiples of the patient’s weight.The primary objective of this study was to evaluate the functional result of inter- and sub-trochanteric femur fractures treated with Proximal Femur Nail Antirotation-II. To improve the rotational stability of the proximal fracture fragment, the trochanteric fixation nail (TFN) was designed. To lessen bone tension at the isthmus, the diameter of the distal tip of the nail was lowered. The research was carried out in the Department of Orthopaedics, Krishna Institute of Medical Sciences, Karad. The research was carried out between June 2019 and June 2021. The Department of Ethics of Krishna Institute of Medical Sciences, Deemed to be University Karad, granted the ethics committee permission. There were 60 individuals in the research who had intertrochanteric and subtrochanteric femur fractures. After receiving informed written consent in the specified way, all participants were included. In summary, PFN A-II is a stable, biomechanically acceptable implant with a clear advantage over other implants for treating stable and unstable intertrochanteric fractures, particularly those in the elderly, and linked with osteoporotic bone. The benefits of the PFN A-II are noticeable with the right surgical approach, with a bare minimum complication rate.
A Clinical Case Study on Janu Sandhivata (Knee Arthritis) to evaluate the effect of Combined Panchakarma procedure and Internal Traditional Ayurvedic Formulations
Authors: Sahu Dipsundar , K. Debnath Saroj , Das Debajyoti , Barik Laxmidhar , Ekka Ranjita , Saha Suparna , K. Madal Tushar , Babu G.
Published: February 2024

Being commonest form of articular disorders Janu Sandhivata (Knee Arthritis) causes a huge hindrance in day to day activities of the sufferer like walking, dressing, bathing etc. It is the disease of old age. It’s mainly effect the weight bearing joint of the body specially knee, hip, lumber spine. As per the Ayurvedic classical references Shula, Sotha, Vata- Poornadriti Sparsha and difficulty in flexion and extension of the Sandhi are the symptoms. There are lots of treatment available in contemporary fields includes NSAID Administration, Intra articular Steroids or eventually surgical intervention in the form of Knee replacement. With this regard there is a need of safe effective and affordable treatment options. In present case study it is tried to explode the Panchakarma procedure like Abhangya, Patra Pinda Shedana therapy, Kashaya Vasti along with few traditional Ayurvedic formulations particularly for Bilateral Knee Osteoarthritis for 30 days duration of treatment it can be concluded that symptoms of severe Osteoarthritis may also be merged with Ayurvedic interventions significantly.
Studi Kinetika dan Penentuan Dosis Optimum Koagulan FeCl3 dalam Menurunkan Konsentrasi Cu2+ pada Larutan
Authors: Fadila Muhammad Seachan , Afandy Moh. Azhar , Suhirman Suhirman , Al Fuady Muhammad Iqbal
Published: February 2024

This study aims to determine the efficiency and adsorption capacity of various concentrations of FeCl3 coagulants (100-300 mg/L) to reduce Cu2+ concentrations in wastewater as well as the kinetic parameters that affect the adsorption mechanism in the coagulation process when coagulant particles added to wastewater will stick to the surface of colloidal particles, which will then change the charge. Several adsorption kinetics models employed in this study include Pseudo-first order, Pseudo-second order, Elovich, and Intra-particle diffusion. The applicability of the models produced in this work was evaluated by optimizing the non-linear equations, which provide values that are more precise and in agreement with real situations when compared to the linear kinetic models. These characteristics are measured based on the value of the coefficient of correlation (R2), Sum Square Error (SSE), and Chi-Square (x2). The results showed that the highest efficiency value of the FeCl3 coagulant was 98.705%, with the value of the adsorption capacity increasing along with the concentration of the FeCl3 coagulant. The kinetic model created in this work has a very excellent fit in terms of experimental data values and prediction data.
Efek Pre-Roasting Terhadap Parameter Kinetika Leaching Cr dari Limonit
Authors: Prameswara Gyan , Ulfah Andi Nurfaadilah , Supriadi Cipta Panghegar , Trisnawati Iga , Petrus Himawan Tri Bayu Murti
Published: February 2024

Hydrometallurgical processes such as leaching of limonite ore to extract valuable metals including Ni and Co are often non-selective, including other metals in the leachate product. The leaching behavior of Cr from the chromite mineral contained in limonite ore is of concern due to the high Cr content of the leachate effluent. The pre-roasted process is frequently used to pre-treat limonite to increase the precious metal content. This study aims to determine the leaching behavior of Cr and the effect of pre-roasting on its kinetic parameters. The pre-roasting process was carried out at 280 and 610 oC for 4 hours. Observation of Cr leaching behavior was carried out in the leaching temperature range of 30-90 oC for 0-120 minutes using sulfuric acid solvent. The highest Cr recovery was achieved in pre-roasted ore leaching at 610 oC with leaching operating conditions of 2 M sulfuric acid, solid-liquid ratio of 5 g/50 mL, 200 rpm, for 120 minutes, at a leaching temperature of 90 oC, under these conditions Cr recovery reached 53.16%. The higher the roasting temperature, the lower the activation energy required for the leaching process. Cr leaching from raw and pre-roasted ore is controlled by the diffusion process through the ash layer with activation energies (EA) of 21.41, 18.64, and 14.71 kJ/mol for raw ore, pre-roasted ore 280 oC, and pre-roasted ore 610 oC, respectively. The comparison of kinetics data from several roasting products for atmospheric leaching feeds will provide industry with information to integrated pyro-hydrometallurgical process to increase Cr production from laterite.
Sentencias comentadas. El control judicial de oficio de las cláusulas abusivas en los procedimientos de ejecución hipotecaria. STC 141/2022, de 14 de noviembre
Authors: Martínez Escribano Celia
Published: February 2024

Desde la STC 31/2019, de 28 de febrero, se viene desarrollando una jurisprudencia constitucional que otorga el amparo frente a la negativa del órgano judicial a realizar un control del carácter abusivo de las cláusulas del contrato de préstamo hipotecario en los procedimientos de ejecución hipotecaria con base en la preclusión y la cosa juzgada, cuando tal control se realiza una vez transcurrido el plazo para formular oposición a la ejecución. Las normas procesales quedan desplazadas para permitir la efectividad de la Directiva 93/13/CEE. Este entendimiento queda ratificado en buena medida con la STJUE de 17 de mayo de 2022, C-600/19, cuyos planteamientos acerca de los sucesivos controles por parte del órgano judicial a pesar de las normas procesales sobre cosa juzgada confirman en buena medida la jurisprudencia constitucional anterior. En este contexto, la STC 141/2022 vuelve a incidir en la necesidad de un control del carácter abusivo de las cláusulas aun después de resolverse la oposición a la ejecución si en ella no se hizo un pronunciamiento expreso sobre alguna cláusula a la luz de la jurisprudencia del TJUE. El modo en que el Tribunal Constitucional resuelve el recurso de amparo en este caso da muestra de la forma en que se articulan las relaciones entre el derecho de la Unión y el derecho a la tutela judicial efectiva en el contexto de las ejecuciones hipotecarias. Tanto los cambios que se han producido en este tipo de procedimientos a la luz del derecho de la Unión Europea como el papel que viene asumiendo el Tribunal Constitucional en relación con la efectividad de la Directiva 93/13/CEE merecen una reflexión que se desarrolla en este trabajo.
Sentencias. A cargo de: Antonio CABANILLAS SÁNCHEZ; Colaboran: Alicia AGÜERO ORTÍZ; Cristina ARGELICH COMELLES, Carlos CASTELLS SOMOZA, Ignacio DÍAZ DE LEZCANO SEVILLANO, Nicolás DÍAZ DE LEZCANO SEVILLANO, Javier FERNÁNDEZ-LASQUETTY MARTÍN, Luis Alberto G
Authors: Cabanillas Sánchez Antonio
Published: February 2024

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La transmisión textual del Memorial “Sacra, católica, real majestad” de Francisco de Quevedo
Authors: Parga Fernando Plata
Published: February 2024

A reappraisal of the textual tradition of Quevedo’s Memorial against the taxation policies of Olivares, which contributed to the writer’s imprisonment at San Marcos in León (1639). An analysis of the variants in 44 manuscripts and two early printed editions yields a complex picture of the tradition of a text that circulated initially in a clandestine, anonymous fashion.
Sátiras contra el rey en la España del siglo XVII
Authors: Usunáriz Jesús M.
Published: February 2024

Satire in verse became a significant element of political culture in the factional struggles at the Spanish court. While the favorites and ministers have been studied in regards to the use of political satire, this work aims to examine the attacks against the king, how these evolved during the Habsburg reigns, and how they shaped a lasting image of the monarchs.
Ícaros y Luciferes: referencias mitológicas y bíblicas en la sátira política del siglo XVII
Authors: Usunáriz-Iribertegui Miren
Published: February 2024

This article aims to analyze the allusive nature of the references in the political satire of the Spanish Golden Age. The identification of some historical figures with episodes from classical mythology or from the Bible is a usual device in the satire about historic characters.
Heartache and Heartbreak: An Observational and Mendelian Randomization Study
Authors: Cai Dihui , Xia Mengming , Chen Xuhui , Yagi Kunimasa , Xu Liang , Wang Bingyu , Wang Yanyi , Zhou Yujie , Liu Jianhui
Published: February 2024

Background: Depression has a significant effect on cardiovascular disease (CVD), but uncertainties persist regarding which modifiable risk factors mediate the causal effects. We aim to determine whether depression is causally linked to CVD and which modifiable risk factors play potential mediating roles.
Methods: We used a two-sample Mendelian randomization (MR) approach and NHANES 2007–2018 data to estimate the effects of depression on various CVD cases and investigated 28 potential mediators of the association between depression and CVD.
Results: The results of our MR analysis indicated that genetically determined depression was associated with increased risk of several CVD, including coronary heart disease (odds ratio (OR) = 1.14; 95% confidence interval (CI): 1.05,1.22), myocardial infarction (OR = 1.19; 95% CI, 1.09,1.31), atrial fibrillation (OR = 1.14; 95% CI, 1.06,1.22), and stroke (OR = 1.13; 95% CI, 1.05,1.22). However, there was no causal association between depression and heart failure. Four out of 28 cardiometabolic risk factors, including hyperlipidemia, hypertension, diabetes, and prescription opioid use, were identified as mediators of the association between depression and various CVDs. Observational association analyses from NHANES data yielded consistent results.
Conclusion: Our findings demonstrated that depression has a causal detrimental effect on various CVDs. Four causal mediators (hyperlipidemia, hypertension, diabetes, and prescription opioid use) were screened to explain the causal effect. Implementing targeted management strategies for these risk factors may be warranted to mitigate the public health burden of CVD among individuals with depression.
Family and inclusive education: exploring the intersection in contemporary school
Authors: Guimarães Willian
Published: February 2024

This paper examines the fundamental role of the family in contemporary society, with emphasis on its evolution and impact on the psychosocial development of its members, as well as on the promotion of school inclusion. Analyzing the theories of Minuchin, Carter, McGoldrick and others, the text highlights the dynamics of the family as an open system that adapts and responds to social changes and individual needs throughout its life cycle. Through a detailed review, it is discussed how the family faces specific challenges at each stage of development, emphasizing the importance of adaptive strategies to maintain its stability and cohesion. The article also addresses the need for inclusive educational policies that recognize and value the diversity of family structures, promoting welcoming and safe learning environments. Collaboration between schools, families and the community is highlighted as essential to support the integral development of students and to build a more inclusive and equitable society. The aim is to highlight the interconnection between family development and inclusive education, encouraging practices that respect and celebrate the diversity of family experiences.
Education for diversity: reflections on school inclusion and relational development
Authors: Guimarães Willian
Published: February 2024

This article presents a qualitative research that explores the experiences of 12 individuals who identify as homosexual, with the aim of understanding how their school experiences influenced the construction of their affective relationships. Through semi-structured interviews, we investigate the challenges faced by these subjects in the school environment, including hostility and prejudice, and how these experiences impacted their ability to form and maintain relationships outside of the school context. The study revealed that family overprotection and the denial of sexuality by families contributed to the development of avoidance strategies and the postponement of the expression of sexuality. Entering relationships was perceived as a moment of affirmation of identity, but also brought additional challenges related to family and social acceptance. The article highlights the importance of inclusive and family-friendly educational environments as key elements for the well-being and healthy development of young homosexuals, pointing to the need for policies and practices that promote acceptance of and respect for sexual diversity.
Teaching experience report in architecture studio
Authors: Calvetti Fernando dos Santos , Brandalise Mariane Pinto
Published: February 2024

This article presents a pedagogical experience in the discipline of single-family residential design in the architecture and urban planning course at the State University of Santa Catarina. We structured a quantitative analysis of the results from the first joint experience of the teachers with a class in the studio. The main objective of the text is to contribute to discussions on the practical and theoretical teaching-learning of architecture. To achieve this goal, we organized the text starting with a brief literature review on active and passive methodologies used in project studios in undergraduate courses. We present an analysis of our journey, culminating in the presentation of the developed project's data and a brief reflection on the performance and results of our students.
On the Value of Sad Music
Authors: Attie-Picker Mario , Venkatesan Tara , Newman George E. , Knobe Joshua
Published: February 2024

Many people appear to attach great value to sad music. But why? One way to gain insight into this question is to turn away from music and look instead at why people value sad conversations. In the case of conversations, the answer seems to be that expressing sadness creates a sense of genuine connection. We propose that sad music can also have this type of value. Listening to a sad song can give one a sense of genuine connection. We then explore the nature of this value in two experimental studies. The results suggest a striking relationship between music and conversation. People see something distinctively musical in works that express precisely those emotions that they think most create connection within conversation.
“The Aberrant Is the Classic”: William Carlos Williams and Literary History
Authors: Cavender Anne L.
Published: February 2024

The “classic” is a vexed term in the work of William Carlos Williams. He uses the category to describe both the stale classicism of T. S. Eliot and Ezra Pound and, conversely, the authentic, “aberrant” classic of James Joyce and surrealism. Analyzing unpublished archival manuscripts alongside the posthumously published collection of essays, The Embodiment of Knowledge, I approach the classic through Williams's theories of pedagogy. Williams parodies and rejects academic modes of reading that cling to the “malignant rigidities” of the past. Yet Paterson and The Embodiment also theorize the reader's interpretive power to disrupt any homogenizing conformity latent in the literary tradition. This dissonant hermeneutics can recuperate the classics and represents a form of resistance to a binary logic of past versus present, or European versus American literature.
Interthematic Polarization
Authors: Dellsén Finnur
Published: February 2024

In recent epistemology, belief polarization is generally defined as a process by which a disagreement on a single proposition becomes more extreme over time. Outside of the philosophical literature, however, “polarization” is often used for a different epistemic phenomenon, namely the process by which people's beliefs on unrelated topics become increasingly correlated over time. This paper argues that the latter type of polarization, here labeled interthematic polarization, is often rational from each individual's point of view. This suggests that belief polarization is not necessarily a failure of individual rationality, but instead a failure of the social structures within which we live our epistemic lives.
Aesthetic Testimony and Aesthetic Concepts
Authors: Sauchelli Andrea
Published: February 2024

I propose a new account of the limits of aesthetic testimony. One of this new account's main claims is that, among the kinds of aesthetic cognitive achievements, it is useful to distinguish aesthetic understanding. In particular, I suggest that the aesthetic understanding of X involves an understanding of why X is aesthetically valuable. In turn, aesthetic understanding is essentially connected to the deployment of aesthetic concepts. Given the fine-grained structure of some of these concepts, certain forms of testimony are not adequate to acquire them.
“The War Songs Continue ’til They Find Peace”: Music and the Politics of Death on the Ethio-South Sudanese Border
Authors: Bishop Sarah J.
Published: February 2024

Discrimination and violence have characterized inter-ethnic dynamics on the Ethiopian–South Sudanese border since the 1990s. Local musicians compose songs decrying the violence, calling for peace in their communities. Simultaneously, these same artists compose songs with divisive rhetoric, particularly during and after outbreaks of ethnically based killings. I argue that this dual promotion of peace and conflict is not contradictory but is logical in the context of decades of violence and trauma. Artists and their listeners consider violence necessary for self-defense, which does not preclude a genuine desire for positive inter-ethnic relations. These logics have implications for applied ethnomusicology in conflict zones.
Stiamo (ancora) tutti bene? L'italiano all'estero: dai primi numeri MLA post-pandemia al mercato del lavoro. Il ‘caso’ della GTA di Toronto
Authors: Casini Simone
Published: February 2024

Il contributo propone una analisi linguistica e politico-linguistico-educativa sulla attuale condizione dell'insegnamento dell'italiano all'estero, a partire dai dati sul numero delle iscrizioni ai corsi di lingua presentati dalla MLA (2022) e dal College Board (AP courses). Il dato generale sui numeri delle iscrizioni ai corsi e sugli esami AP è poi considerato a titolo esemplificativo nel contesto economico professionale della Greater Toronto Area (GTA) di Toronto, così da fornire un quadro specifico, ma esaustivo, delle opportunità di spesa delle competenze linguistiche in italiano in un contesto come quello della capitale dell'Ontario che è stato nel passato particolarmente attrattivo per l'Italia e l'italiano a seguito degli ingenti movimenti migratori degli anni Settanta e Ottanta.
God and State Above All
Authors: Cornett Natalie
Published: February 2024

This article explores how politically active Polish women starting in the late nineteenth century until the start of World War II viewed themselves and their duties vis-a-vis the Polish nation. It traces the women's movement in Poland from the first calls for women's right to work, to their eventual enfranchisement under a newly independent Polish state in 1918. Challenges to women's equality took many forms: men from both sides of the political spectrum viewed women's entry into the salaried workforce and the public sphere as largely undesirable and deployed a variety of arguments to reinforce traditional gender hierarchy. Yet many educated Polish women, even from conservative, Catholic perspectives, viewed their engagement in the public sphere as necessary work for the good of the Polish nation. This article uses letters, political pamphlets, and published works to explore how modern Polish women attempted to strike a balance between breaking and preserving traditional notions of gender in order to secure new rights for themselves in a volatile political atmosphere. While Polish women's groups differed on their vision of the ideal Polish state, they generally agreed that women's roles as mothers provided the moral legitimacy required to act in the public sphere. They successfully carved a space for themselves in the new Polish state of 1918 but remained marginalized in a separate and unequal status in the interwar period.
It Is High Time for Serious Women
Authors: Dobkowska-Kubacka Joanna
Published: February 2024

This article aims to highlight aspects of female emancipation in the Kingdom of Poland in the second half of the nineteenth century that gave this movement a specific, national character. The political and economic consequences of the January Uprising (1863–1864) hit the landed gentry particularly hard. As a result, many gentry women faced the necessity of earning a living and this forced a change in their way of life and aspirations. The traditional model for elite women did not match the economic challenges, and with this in mind, the Polish press, especially magazines for female readers, aimed to create a new model of gentry womanhood. Most periodicals agreed that women's emancipation was on a certain level necessary. But to what extent? This question has been a subject of dispute. Some columnists postulated to limit women's professional aspirations to manual occupations in order to preserve the domain of prestigious intellectual labor exclusively for men. This conservative movement succeeded only partially, with some upper-class women devoting themselves to handicrafts while others, against conservatives’ wishes, graduated from universities abroad and obtained qualifications for performing previously male professions. The majority of these educated women combined paid labor with social work. They were strongly influenced by the promoted ideal of a “new Polish woman” who was to be hard working, constantly improving her mental faculties, and engaging in activities that benefitted Polish society and the nation. This model contributed significantly to the formation of a new generation of distinguished female activists.
Business Participation in the Implementation of Child-Friendly City Policy in Depok City
Authors: Adibrata Muhammad Arjuna , Purwanto Agus  Joko , Rulinawati Rulinawati
Published: February 2024

The implementation of child-friendly city policies plays a pivotal role in ensuring the well-being and optimal development of children within urban environments. This article explores the significant involvement of the business sector in supporting the implementation of child-friendly city policies in the context of Depok City. The engagement of the business sector, facilitated by the Association of Indonesian Child-Friendly Companies (Asosiasi Perusahaan Sahabat Anak Indonesia or APSAI), along with the principles of Corporate Social Responsibility (CSR), forms a crucial partnership with the government and the community to create an environment that nurtures the growth of children. This article discusses the multifaceted contributions of the business sector, focusing on financial investments, infrastructural development, educational initiatives, and collaborative efforts aimed at enriching the lives of children in Depok City. It delves into the model of Van Meter and Van Horne (1975) to analyze the factors influencing the implementation of child-friendly policies and elaborates on the distinctive roles APSAI and CSR play in supporting this endeavor. By examining these roles comprehensively, the article underscores how collaborative efforts among the government, the community, and the business sector can holistically foster a city that prioritizes the rights and well-being of its youngest inhabitants. Ultimately, this article highlights the significance of leveraging business resources, expertise, and commitment to contribute to the realization of a child-friendly urban environment. It underscores the importance of fostering partnerships, effective communication, and continuous coordination between these stakeholders to ensure the successful implementation and sustainability of child-friendly city policies in Depok City
IMPACT OF ANTENATAL STEROID ADMINISTRATION ON NEONATAL RESPIRATORY OUTCOMES
Authors: HAQ W , NAZ N , TAJ S , ARSH . , BHITTANI R
Published: February 2024

The administration of antenatal steroids represents a pivotal intervention in obstetric care with profound implications for neonatal respiratory outcomes. The study's main objective is to find the impact of antenatal steroid administration on neonatal respiratory outcomes. This retrospective cohort study was conducted at Lady Reading Hospital Peshawar from July 2019 to June 2023. The study included all infants born at the hospital who met the criteria for preterm birth (gestational age less than 37 weeks). Maternal demographic information was extracted, encompassing maternal age, parity, and medical history. The data collection's primary focus was antenatal steroid administration, including the type of steroid used, dosage, and timing of the gestational age at delivery. Data was collected from 550 preterm infants. The mean maternal age in the antenatal steroid group was 28.5 ± 4.2 years, and 29.1 ± 4.5 years in the no antenatal steroid group. The mean gestational age was 32.2 ± 2.1 weeks and 31.8 ± 2.3, respectively, in both groups. In the antenatal steroid group (n=300), the majority received betamethasone (90.0%) compared to dexamethasone (10.0%). The timing of administration varied, with 16.7% receiving steroids before 28 weeks, 50.0% between 28-32 weeks, and 33.3% between 32-34 weeks. The mean dosage for betamethasone was 10.5 ± 2.3 mg, while dexamethasone had a mean dosage of 8.0 ± 1.5 mg. It is concluded that antenatal steroid administration was associated with a significant reduction in RDS incidence and a lower need for mechanical ventilation among preterm infants. These findings emphasize the clinical importance of timely antenatal steroid administration in improving neonatal respiratory outcomes.
ROLE AND ELEVATING PROGNOSTIC PRECISION OF PIVKA-II AS A SUPERIOR BIOMARKER IN HCC DIAGNOSIS, SURPASSING AFP
Authors: YASEEN M , ANWAR R , AHMAD MM , JAVAID H , SADIA M , BUTT MR
Published: February 2024

The objective of this study was to evaluate the diagnostic accuracy of PIVKA-II as compared to AFP for the detection of hepatocellular carcinoma (HCC) and its potential as a devoid prognostic biomarker. With genomic discoveries, including gene mutations, epigenetic alterations, and non-coding RNAs, the context around HCC biomarkers has increased. The relevance of prognostic and predictive biomarkers is growing as they support treatment choices and evaluate clinical outcomes. These indicators are significant tools in enhancing patient care because they improve diagnosis, direct therapy, forecast outcomes, and evaluate treatment responses. Comprehensive information on the predictive value of several markers, however, is still lacking. In this study, 85 people took part, including those older than 18 with hepatocellular carcinoma in a range of clinical stages. Three groups represented the study population, comprising 85 individuals in total: group 1 consisted solely of patients with HCC, group 2 included patients with benign liver disease, and group 3 was designated as the control group. A male predominance is found in groups, except group 2. The quantity of PIVKA-II in serum was measured using an automated analyzer that was based on the CMIA. The immunoassay method was applied to determine the concentration of AFP. The statistical analyses of PIVKA-II and AFP consisted of sensitivity 90–99% and 58–81%, specificity 68–99%, and 61–98% with a 95% CI, respectively. The findings emphasize PIVKA-II's superior performance as a biomarker of cancer response when compared to AFP.
Nutrological aspects of polyphenols and gut microbiota in sports performance: a systematic review
Authors: Crepaldi Lara Souza , Teixeira Thuany da Silva , Braga Mariana Carolina , Oliveira Alessandra Leal de , Azevedo Lucas Emanuel de Lima , Azevedo Renata Cristina Taveira , Cordeiro Nathalia Galindo , Carvalho Rodrigo siqueira de
Published: February 2024

Introduction: In the context of nutrology and sports performance, the focus for intake in athletes and physically active individuals has been directed to the main class of polyphenols. Interest in a personalized approach is increasing in sports to maximize each individual's athletic ability in endurance and strength sports. Polyphenols represent a heterogeneous class of compounds with marked antioxidant and anti-inflammatory properties. The impact of the gut microbiota on the bioavailability and activity of polyphenols is highlighted. Objective: It was to carry out a systematic review to highlight the main relationships between polyphenols, gut microbiota, and sports performance. Methods: The systematic review rules of the PRISMA Platform were followed. The research was carried out from May to July 2023 in Scopus, PubMed, Science Direct, Scielo, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: A total of 115 articles were found, and 81 articles were evaluated in full and 76 were included and developed in this systematic review study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 6 studies with a high risk of bias and 10 studies that did not meet GRADE. As a result and conclusion, it was shown that the metabolic mechanisms favored by polyphenols improve sports performance, improve cardiometabolic functions, reduce recovery times and post-exercise pain, maintain a low degree of oxidative stress, and avoid unregulated inflammatory processes. Thus, polyphenols are able, through their interaction with the gut microbiota, to favor the proliferation of bacterial genera of great importance for metabolic and cognitive functions, such as Akkermansia, Lactobacilli, and Bifidobacteria. Gut microbiota metabolizes polyphenols in the colon to produce small bioactive molecules that exert epigenetic mechanisms on biochemical pathways modulating gene expression. Polyphenols have multiple biological effects, and future exercise studies should be appropriately and specifically designed to determine the physiological interactions between exercise and the selected supplement, rather than just considering performance.
Effect of Partial Doping with La Atoms on Some Superconducting and Electrotransport Characteristics of Y1-x LaxBa2Cu3Oy Polycrystals
Authors: Nikoghosyan S. K. , Sargsyan A. G. , Zargaryan Y. G. , Aivazyan A. , Hakopyan A.
Published: February 2024

The effect of the location with different concentrations of La atoms (x = 0; 0.02; 0.028; 0.11) on some superconducting and electrotransport characteristics of Y1−xLaxBa2Cu3Oy polycrystalline compounds was studied by recording the temperature dependence ρ(T) curves of resistivity in the case of direct current in the range of temperatures (77K - 300K). The temperatures at the onset (Τcon) and offset (Tc0) of the transition, as well as the width of the transition - ΔΤc = Τcon-Tc0, were considered as the superconducting characteristics. The absolute values of ρ(300K) and ρ(100K) and their ratio a = ρ(300K)/ρ(100K) were considered as electric transport characteristics, as well as the temperature coefficient of resistivity dρ/dT, which was determined by ρ(T) in the range of linear dependence with the slope of the curve. From the comparison of these characteristics, it was concluded that there is a certain correlation between the superconducting and electrotransport properties of the studied compounds depending on the concentration x of the partial location of Y atoms with La.

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Miniaturized Microstrip Patch Antenna on YIG Material Under External Magnetic Field
Authors: Stepanyan A. , Haroyan H. , Hakhoumian A.
Published: February 2024

This paper discusses an electrically small microstrip patch antenna that utilizes biased yttrium iron garnet (YIG) ferrite material. The study explores how the presence of an external magnetic field influences the bandwidth and radiation properties of the patch antenna. The antenna design is focused on operating at a frequency of 1.5 GHz. The utilization of biased YIG magnetodielectric material in the patch antenna results in an approximate threefold reduction in size compared to a patch antenna based on FR4 dielectric. Additionally, the antenna achieves a remarkable threefold increase in bandwidth, reaching 280 MHz at 1.5 GHz center frequency.
Formation of a Diffraction Field During Dynamic Scattering of Slow Neutrons in a Deformed Crystal
Authors: Shahverdyan A. V.
Published: February 2024

The problem of diffraction of slow neutrons with a de Broglie wavelength λ ~10-10 m in a crystal with a deformed lattice is considered. Based on the Hamilton equations describing the dynamic diffraction of slow neutrons, the features of the formation of a dynamic diffraction field in a lattice in various regions of the deformation field characteristics, including weak fields, slowly changing fields and rapidly changing fields are discussed. Using a particular example of a deformation field with a displacement field quadratic in coordinates, analytical solutions are obtained for the wave functions of transmitted and reflected lattice waves.
Machine learning-based biomarkers for breast cancer molecular subtypes HER2+ and TNBC
Authors: Yasar Seyma
Published: February 2024

Breast cancer is the most common type of cancer and the leading cause of death in women in Türkiye and worldwide. Since breast cancer tumor cells have different genetic characteristics, diagnosis and treatment options vary according to molecular subtypes. The primary objective of this study is to classify human epidermal receptor 2 positive (n=71) and triple-negative breast cancer (n=25) molecular subtypes using two different machine learning algorithms based on tissue proteomics data of 96 breast cancer patients. The secondary aim was to identify possible protein biomarkers that could be used to determine the diagnosis and treatment of these molecular subtypes. The upper sampling method was used to overcome the class imbalance in the study data. The least absolute shrinkage and selection operator (Lasso) was used as the variable selection method. In the modeling phase, Extreme Gradient Boosting (XGBoost) and Bootstrap Aggregating Classification and Regression Trees (Bagged CART) machine learning methods were used. The best classification performance is XGBoost, whose accuracy, balanced accuracy, sensitivity, specificity, positive predictive value, negative predictive value, F1 score, MCC and G-mean values are 96.4%, 96.4%, 100%, 92.9%, 93.3%, 100%, 96.6%, 93.1%, 96.6%, respectively. The three protein access codes found to be most important for the classification of the two molecular subtypes in the optimal model XGBoost result are P02042, P00441 and P20231. These three proteins are thought to be clinically useful markers for early diagnosis and individualized treatment.
An observational study to determine the category and causes of the drug-related problems among geriatric inpatients
Authors: Naik Yogita , Muraraiah Sushma , Lokesha Rohit
Published: February 2024

Background: Geriatric patients are at a higher risk of drug-related problems (DRPs) because of age-related chronic diseases leading to the use of numerous therapeutic regimens, and pharmacokinetic and pharmacodynamic changes. DRPs are associated with reduced quality of life, increased hospital admissions, prolonged hospital stays, and increased health-care costs.

Aims and Objectives: This study aimed at identifying the category and causes of DRPs so that better strategies can be framed, thereby improving the quality of health care.

Materials and Methods: The observational study was conducted among geriatric inpatients in a tertiary care hospital. The DRPs were identified using national and international standard guidelines. The Pharmaceutical Care Network of Europe (PCNE) classification version 9.01 was used to determine the category and causes of DRPs in the patients.

Results: Seventy patients were enrolled in the study. A total of 102 DRPs were detected among these patients. The mean number of DRPs per patient was 1.45. According to the PCNE classification, 36 DRPs were related to treatment effectiveness, 27 were related to treatment safety, 25 were unnecessary drug treatments and 14 were related to cost effectiveness of the treatment. One hundred and fifty-one causes of DRPs were identified. The most commonly involved class of drugs in DRPs was antimicrobials.

Conclusion: The number of DRPs noted in the present study was lower than those in the other studies. Majority of DRPs were treatment effectiveness-associated and caused due to errors in drug selection and use.
TEACHING LITERACY FOR THOSE WHO TELL LIFE STORIES: A PROPOSAL FROM THE 6TH DIREC OF RN TOGETHER WITH THE POLICY TO ERADICATE ILLITERACY, QUALITATIVE ANALYSIS FROM THE PERSPECTIVE TOLD BY LITERATE PEOPLE
Authors: Da Silva Alenberg Aquino , E Silva Francisca Fabiana de Sousa , Da Silva Dinorá , Santiago Nilza Martins , Santos Maria Dalva da Silva , Dantas Francisco Bruno Silva , Dantas Luiza Beatriz Olegário Silva , Da Silva Francisco Wallyson Bezerra , Da Silva Luciano Henrique Pereira , Andrade Maria Aldeni de Oliveira
Published: February 2024

The problem of illiteracy represents a significant challenge in many parts of the world, negatively impacting the socioeconomic development and quality of life of communities. Illiteracy refers to the inability to read and write, limiting access to crucial information and educational, economic and social opportunities. This issue is complex and multifaceted, being influenced by several factors, such as poverty, lack of educational infrastructure, gender discrimination, armed conflicts, and the absence of effective literacy programs. The intergenerational cycle of illiteracy also plays a role, as non-literate parents are more likely to have children in the same situation. The program "Alphabetizing those who tell life stories" was designed by SEEC/RN and shaped by the state's 6th education directory, with the aim of rescuing citizens who never attended school or had little time in the school community. The methodology used included a case study and the application of interviews with subjective answer questions, in addition to training research on the participants' life stories. The results revealed that the majority of interviewees abandoned their studies due to the lack of conditions at the time, and were directed to work. However, everyone expressed a desire to return to studying before being invited to the program. Participants praised the program's approach, highlighting that every school should follow the same model. The qualitative analysis of the responses showed that the program positively impacted their lives from a human and social point of view, providing a new perspective of integration into society.
POSITIVISM AGAINST FASCISM: THE BIFURCATIONS OF CONSERVATIVE POLITCS
Authors: Pinheiro Maxmiliano Martins
Published: February 2024

Faced with the polysemy imputed to the terms positivism and fascism, this article aims to highlight, in the political aspect, the differences between the first and the second, although both are considered by many scholars to be expressions of an authoritarian conservative thought. Thus, it is necessary to present three specific objectives that elucidate two singularities and divergences, namely: the emphasis on the centralism of political leaderships, the quarrels regarding communist and socialist prerogatives, and the examination of the entry of the masses into the political context. Such objectives will be unfolded based on some aspects of Augusto Comte's political sociology and some vectors that characterize the modus operandi of fascism. It is hoped that this analysis will clarify that, while Comte's positivism is based on rationality, on the functionalism of ideas and on the limited participation of social strata, fascism is based on the excessive idealization of the historical context, on the intolerance of opposing political currents and in the political and manipulated empowerment of the masses.
Studi Komparatif Pengelolaan Sanitasi dengan Keberadaan Jentik di kawasan Pesisir dan Pegunungan di puskesmas Pamandati
Authors: Soraya.M Shindy Aprilia , Gerung Jumartin , Sitti Marya Ulva
Published: February 2024

Kawasan pesisir dan pegunungan memberikan perbedaan dalam proses pengelolaan sanitasi serta proses berkembangbiaknya jentik nyamuk Aedes Aegepty. Hasil observasi yang dilakukan di Puskesmas Pamandati terdapat desa dikategorikan pengeleloaan sanitasi baik tetapi ditemukan kasus DBD, sedangkan desa pengeleloaan sanitasi tidak baik tidak ditemukan kasus DBD. Penelitian ini bertujuan untuk melihat perbedaan pengelolaan sanitasi dengan keberadaan jentik di wilayah pesisir dan pegunungan. Penelitian menggunakan studi perbandingan dengan pendekatan cross sectional. Jumlah sampel pada penelitian sebanyak 70 responden diwilayah pesisir dan 74 responden diwilayah pegunungan menggunakan rumus Slovin, dengan teknik penarikan sampel menggunakan Proportional Stratified Random Sampling. Metode analisis menggunakan uji statistic Chi-Square. Hasil penelitian ini dengan menggunakan X2tabel =3,841, menunjukkan adanya hubungan tempat penampungan air dengan keberadaan jentik pada wilayah pesisir dengan nilai X2 hitung = 8,403, sedangkan wilayah pegunungan tidak ada hubungan dengan nilai X2 hitung = 0,016. Diharapkan bagi masyarakat baik diwilayah pesisir maupun pegunungan untuk mengikuti kegiatan penyuluhan kesehatan yang diselenggarakan pihak puskesmas dan memperhatikan kebersihan lingkungan.
Pengaruh Media Leaflet Terhadap Tingkat Pengetahuan dan Sikap Ibu Dalam Pencegahan Diare Pada Balita di Desa Amesiu Kecamatan Pondidaha Kabupaten Konawe
Authors: Nurul Aulia Nisa  , Sunarsih  , M. Idrus
Published: February 2024

Puskesmas Pondidaha merupakan salah satu Puskesmas di Desa Amesiu Kecamatan Pondidaha dengan jumlah kasus diare tertinggi se-Kabupaten Konawe. Pada tahun 2021 jumlah kasus diare sebanyak 32 kasus, sedangkan pada tahun 2022 meningkat sebanyak 47 kasus diare dari jumlah 186 balita yang ada di Desa Amesiu. Jenis penelitian ini adalah quasi-eksperimental dengan rancangan pre-post test control group design. Populasi dalam penelitian ini adalah seluruh balita yang ada di Desa Amesiu yang berjumlah 186 responden. Besar sampel sebanyak 66 responden, yang diambil secara simple random sampling. Data diperoleh menggunakan kuesioner kemudian dianalisis secara deskriptif dan inferensial menggunakan uji Mc. Nemar. Hasil penelitian menunjukkan bahwa pemberian leaflet berpengaruh terhadap pengetahuan responden P-value = 0,063. Pemberian leaflet berpengaruh terhadap sikap responden P-value = 1,000. Diharapkan kepada masyarakat Desa Amesiu untuk meningkatkan pengetahuan terkait upaya pencegahan diare pada balita dan mampu menerapkan perilaku hidup bersih dan sehat agar dapat terhindar dari penyakit yang dapat disebabkan oleh faktor lingkungan.
Faktor-Faktor Yang Berhubungan Dengan Kejadian Diare Pada Balita di Wilayah Kerja Puskesmas Motui Kabupaten Konawe Utara
Authors: Nei Nei intan , Kadarman Achmad , Rasyid Sri Anggarini
Published: February 2024

Insiden diare semua umur secara nasional adalah 270/1.000 penduduk. Target cakupan pelayanan penderita diare pada balita yang datang ke sarana kesehatan adalah 10% dari perkiraan jumlah penderita Diare balita. Cakupan pelayanan penderita diare Balita untuk Provinsi Sulawesi Tenggara sebesar 26,59%. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan kejadian diare pada balita di Wilayah Kerja Puskesmas Motui Kabupaten Konawe Utara. Jenis penelitian ini adalah penelitian kuantitatif analitik dengan desain cross sectional study, Populasi dalam penelitian ini adalah 790 ibu yang memiliki balita. Jumlah sampel 88 orang. Teknik pengambil sampel menggunakan teknik simple random sampling. Metode analisis menggunakan uji chi-square dan uji phi. Hasil penelitian menunjukkan bahwa ada hubungan lemah status gizi dengan kejadian diare (X2hitung = 4,940 > X2tabel = 3,841). Ada hubungan lemah pemberian ASI ekslusif dengan kejadian diare (X2hitung = 3,629 < X2tabel = 3,841) dan ada hubungan lemah sanitasi sanitasi dasar dengan diare (X2hitung = 4,205 > X2tabel = 3,841). Disarankan bagi masyarakat agar mencari informasi tentang penyakit diare.
Comparison of the English Versions of Poem Lu Zhai
Authors: Zhao Xuefei
Published: February 2024

Chinese classical poetry, as a treasure of Chinese culture, has always attracted numerous translators. Translating classical poetry not only requires accurately conveying the artistic conception and expression of the original work, but also requires flexible application of translation techniques to adapt to different language and cultural backgrounds. Poetry translation is a difficult point in the translation of literary works, and poetry is known as “literature in literature”. Its form is brief but its meaning is profound, “words are here and meaning is there, words are full and meaning is infinite”. This article will take the classic Chinese classical poem “Lu Zhai"”as an example, and use the method of literature review to collect and analyze G W. Translated versions by two translators, G.W. Robinson and Xu Yuanchong. Firstly, a comprehensive reading and understanding of the two versions were conducted. Secondly, by comparing the translation styles of the two versions, we compared rhyme, image, sentence as well as arrangement. Through these comparisons, the article draws conclusions about the different stylistic characteristics of the two translators. This study is of great significance in revealing translators’ understanding and expression of classical poetry.