bluuebunny/crossref_metadata_2025 huggingface dataset:
Hubungan Prestasi Belajar dan Motivasi Belajar Dengan Minat Meneruskan Pendidikan Peserta Didik
Authors: Nurdin Gaby Maulida , Wahid Masyitha , Mardiana Mardiana
Published: March 2023

Setiap siswa memiliki motivasi belajar dan prestasi belajar yang berbeda sehingga minat atau dorongan untuk menempuh pendidikan yang lebih tinggi juga berbeda. Tujuan dari penelitian ini adalah (1) untuk mengetahui hubungan antara motivasi belajar dengan minat melanjutkan pendidikan peserta didik kelas XII MIPA SMA Negeri 1 Majene (2) untuk mengetahui hubungan antara prestasi belajar dengan minat melanjutkan pendidikan peserta didik kelas XII MIPA SMA Negeri 1 Majene. (3) untuk mengetahui hubungan antara prestasi belajar dan motivasi belajar dengan minat melanjutkan pendidikan peserta didik kelas XII MIPA SMA Negeri 1 Majene. Populasi penelitian yaitu seluruh siswa  kelas XII MIPA SMA Negeri 1 Majene dengan jumlah 156 orang. Adapun teknik pengambilan sampel menggunakan teknik simple random sampling yang terdiri atas 112 siswa dengan perwakilan masing-masing kelas XII MIPA. Pengumpulan data motivasi belajar dan minat siswa untuk melanjutkan pendidikan menggunakan angket yang disebarkan dalam bentuk google form melalui aplikasi WhatsApp, dan pengumpulan data prestasi belajar menggunakan nilai rapor (evaluasi kognitif) peserta didik kelas XI MIPA pada pelajaran biologi semester genap tahun pelajaran 2020/2021. Hasil penelitian ini adalah (1) terdapat hubungan antara motivasi belajar dengan minat melanjutkan pendidikan pada peserta didik kelas XII MIPA SMA Negeri 1 Majene diketahui dari nilai signifikansi (0,000). (2) tidak terdapat hubungan antara prestasi belajar dengan minat melanjutkan pendidikan pada peserta didik kelas XII MIPA SMA Negeri 1 Majene yang ditunjukkan melalui nilai signifikansi (0,141). (3) terdapat hubungan antara motivasi belajar dan prestasi belajar dengan minat melanjutkan pendidikan pada peserta didik kelas XII MIPA SMA Negeri 1 Majene dengan melihat nilai signifikansi (0,000).
Pemodelan Matematika SIR dengan Pengaruh Vaksinasi pada Penyebaran Covid-19 di Sulawesi Selatan
Authors: Abdy Muhammad , Rifandi Muhammad
Published: March 2023

Penelitian ini bertujuan untuk menyusun model SIR pada penyebaran COVID-19 dengan pengaruh vaksinasi, analisis kestabilan dan simulasi model SIR pada penyebaran COVID-19 di Sulawesi Selatan. Metode yang digunakan untuk membangun model adalah model persamaan diferensial dengan mempertimbangkan faktor vaksinasi sebagai parameter, analisis model menggunakan metode matrix next generation  untuk menentukan bilangan reproduksi dasar dan kestabilan model penyebaran COVID-19. Simulasi model numerik menggunakan data sekunder jumlah kasus COVID-19 di Sulawesi Selatan. Hasil yang diperoleh adalah Analisis model memberikan bukti kestabilan titik kesetimbangan. Berdasarkan hasil yang diperoleh juga dapat dilihat bahwa vaksinasi sangat berpengaruh terhadap penyebaran covid-19, sehingga diperlukan adanya kesadaran bagi masyarakat Sulawesi Selatan untuk mengikuti anjuran pemerintah agar melakukan vaksinasi hingga tiga kali guna mencegah atau menurunkan laju penularan covid-19. Berdasarkan hasil perhitungan bilangan reproduksi dasar, diperoleh R0 = 0.653784 sehingga dapat dikatakan bahwa keadaan penularan penyakit covid-19 di Provinsi Sulawesi Selatan sudah terkendali.
Адипонектин та його біологічні ефекти
Authors: Dombrovska N. S.
Published: March 2023

Відповідно до сучасних уявлень, жирову тканину вважають ендокринним органом, а ожиріння – захворюванням, що характеризується хронічним системним низькоградієнтним запаленням. Жирова тканина синтезує «адипокіни», в тому числі й адипонектин, інтерес до якого зумовлений багатьма ефектами (інсулінсенсибілізуючий, антиоксидантний, імунологічний, кардіопротективний, антиатерогенний, безпосередня участь у метаболізмі жирних кислот, глюкози тощо). Численні клінічні дослідження показали, що зниження концентрації адипонектину пов’язане з розвитком інсулінорезистентності та цукрового діабету типу 2, проте механізми залишаються нез’ясованими.
Гормонально-метаболические нарушения у больных с артериальной гипертензией и сахарным диабетом типа 2
Authors: Bilovol O. M. , Bobronnikova L. R. , Al-Trawneh O. V.
Published: March 2023

В статье рассмотрены особенности метаболических нарушений во взаимосвязи с концентрацией цинк-α -гликопротеина и его влияние на течение и прогрессирование артериальной гипертензии (АГ) и сахарного диабета (СД) типа 2. Обследовано 47 больных с АГ II стадии, ожирением ІІ степени в сочетании с СД типа 2 и 49 больных с АГ II стадии, ожирением ІІ степени без СД типа 2. Установлено прогрессирование гормонально- метаболических нарушений у больных с сочетанным течением АГ и СД типа 2. Наиболее значимыми были инсулинорезистентность, нарушения углеводного обмена, развитие атерогенной дислипидемии и системного воспаления, которые находятся во взаимосвязи со снижением концентрации цинк-α -гликопротеина в сыворотке крови, что способствует высокому сердечно-сосудистому риску.
Influence of the traditional therapy and its combination with Thiotriazolin® on dynamics of the endogenous intoxication indicators, cytological composition of sputum and adaptive responses of the patients with community-acquired pneumonia
Authors: Iliuk I. A. , Shevchuk S. V. , Postovitenko K. P. , Leshchenko S. I. , Galiutina O. Yu. , Bezsmertna G. V. , Shevchuk O. V. , Saienko A. V.
Published: March 2023

The article presents the problem of treatment rates improvement of the patients with community-acquired pneumonia as a result of inclusion of Thiotriazolin® metabolic correction and analysis of the clinical treatment rates in the complex of therapeutic measures. Inclusion of Thiotriazolin® in the treatment complex provided faster normalization of sputum cytogram, significantly reduced the level of the endogenous intoxication, which led to the increase in the number of favorable adaptive responses of the organism, more significantly than the traditional therapy, reduced the intensity of the inflammatory response in the lungs and reduced the time of elimination of the clinical disease.
Sleep disorders, associated with anxiety and depressive disorders, and their corrections peculiarities in the oncogynecological practice
Authors: Vasylyeva G.
Published: March 2023

30–75 % of patients with visualized forms of malignant tumors suffer from sleep disorders, which are comorbid with anxiety and depressive disorders. With the purpose of detection and correction of sleep disorders associated with anxiety-depressive disorders in patients with malignant neoplasms of the female reproductive system we study an emotional condition of 210 patients with reproductive organs’ malignant tumors. Insomnia disorders were detected in (72.4 ± 3.1) % patients suffering from reproductive organs’ malignant neoplasms. According to the ICD-10, emotional disorders accompanied by insomnia were presented by anxious and depressive disorders within symptomatic anxiety disorder (11.4 % ± 2.2 %), symptomatic depressive disorder (31.0 % ± 3.2 %), and adjustment disorder with prolonged depressive reaction (5.2 % ± 1.5 %), mixed anxiety and depressive reaction (11.4 % ± 2.2 %) and prevalence of anxiety reactions (13.3 % ± 2.3 %). In the structure of insomnia in patients suffering from malignant neoplasms presented presomnic (79.5 % ± 2.8 %), intrasomnic (40.9 % ± 3.2 %) and postsomnic disturbances (27.1 % ± 2.6 %). In our research we revealed a combination of pre-, intra- and postsomnic disturbances (47.3± 4.6 %). According to the Insomnia Severity Index the severity of insomnia in cancer patients was higher in the structure of symptomatic anxiety and depressive disorders than in the structure of adaptive disorders. After 4 weeks complex treatment a significant decrease in the severity of insomnia, depression and anxiety noted. In-time diagnosis and correction of insomniac disorders associated with anxiety-depressive disorders in cancer patients is a prerequisite for the success of specific antitumor treatment, improving the quality and duration of their lives.
Карбокситерапия – стиль Off-label use (лекарственные средства вне инструкции)
Authors: Chernykh V. P. , Drogovoz S. M. , Zupanets І. A. , Sіroshtan G. M. , Zupanets M. V. , Kornienko V. I. , Drogovoz E. V.
Published: March 2023

Во врачебной практике часто встречаются ситуации, при которых врач берёт на себя ответственность за принятое им нестандартное решение при назначении лекарствен- ного средства. «Off label use» терапия – применение препарата по показаниям, не утверждённым государственными регулирующими органами и/или не упомянутыми в инструкции по применению. Примером назначения «off label use» является карбокситерапия (лечение углекислым газом). Благодаря физиологическим свойствам СО2 карбокситерапия обладает аналгезирующим, антиоксидантным, сосудорасширяющим, противовоспалительным, спазмолитическим действием, нормализует вязкость крови и оксигенацию тканей, стимулирует процессы неоангиогенеза и регенерации. Таким об- разом, карбокситерапия занимает важное место в фармакотерапии без наличия реко- мендаций в медицинских формулярах благодаря разнообразной фармакодинамике, безвредности и 30-летнему эффективному клиническому опыту.
Reproductive health of women with early miscarriages in anamnesis associated with vaginal dysbiosis
Authors: Fedyshyn T. V. , Maliar V. A.
Published: March 2023

The article deals with comparative analysis of investigation on the basis of clinical statistics taken from archival medical histories in women with miscarriages in anamnesis associated with vaginal dysbiosis. Disorders of reproductive health in women with early reproductive loss are mostly manifested and typical for women with recurrent incompetent pregnancy. It is offered to use clinical markers as possible predictors of incompetent pregnancy.
Спосіб корекції клімактеричних порушень у жінок перита післяменопаузального віку
Authors: Horbatiuk O. H.
Published: March 2023

Наведено дані про новий спосіб корекції клімактеричних порушень за допомогою трансдермальної терапевтичної системи «Евра». Проведено порівняння з препаратами, використовуваними для традиційної замісної гормональної терапії. Доведено медичну та економічну ефективність трансдермальної терапевтичної системи «Евра» з усунення ранніх клімактеричних проявів у жінок пери- та післяменопаузального віку.
The psychology of health in the context of the radical crisis situations of globalized century
Authors: Holovaty M. F. , Holich O. M.
Published: March 2023

The purpose of this publication is to raise and actualize the scientific consideration of the problem of mental health, which in the context of large-scale globalization processes acquired an extremely acute character in the third millennium. Attention is focused on the fact that a holistic, integrated and synergetic study of mental health, especially in Ukrainian scientific thought, is still not enough. The practical importance of the problem under study, in turn, concerns the deepening of the theoretical and methodological approach to the disclosure of the essence, features, significance of mental health in modern conditions, intensive and often bearing in itself constant threats to the lives of individuals and large social groups. The social significance of the problem under investigation is that the theoretical developments on this issue should be encouraged to develop public policies, programs, practical tools, technologies, methods of strengthening mental health, as a factor that seriously affects the healthy way of life of a person.
"Health" construct in the structure of consciousness of student youth
Authors: Falkovska L. M. , Havrylovska K. P. , Mizichko L. V.
Published: March 2023

The article reveals the results of empirical research of social ideas of students about health, namely – the features of systematization, the content of this construct, and the presence of line of conduct of recreational behaviour in young people`s minds. The methodological basis is principles of the theory by S. Moskovichi on the essence and nature of social ideas which construct and define the social nature of cognition of certain groups and indicate a certain attitude towards social objects. It has been proved that the most appropriate in these circumstances is the application of the psychosemantic method (by V. F. Petrenko), which allows to study features of stable social ideas of student youth regarding health by means of using the capacities of the Statistics 13.0 program. The article states that subjective ideas regarding the health status of freshmen and fourth-year students differ in the direction of increasing realism and absence of declarativeness in judgments of senior students. Reconstruction of the psychosemantic space of "health" construct revealed four relatively independent factors: "health-promoting circumstances", "evidence of health", "methods of health-improvement" and "health benefits" which determine the main tendencies in the attitude of student youth to health. In accordance with the obtained results, the conclusions have been made on the necessity of developing state, public and personal programs which should orient, organize and motivate young people towards choosing actually effective health practices.
Тhe peculiarities of the formation of mental health among students of higher education institutions
Authors: Turynina O. L.
Published: March 2023

The publication is an attempt to deal with the peculiarities of the formation of mental health among students of higher education institutions. A brief analysis of theoretical and empirical research on the mental health of students is presented. The main attention is focused on the lack of a coherent system of research in psychological literature. The current theoretical and methodological aspects of this topic are discussed and a methodical toolkit consisting of a set of methods and techniques, in particular on an author's questionnaire, aimed at studying the determinants of person' mental health, is presented. The work focuses on the creation of a psychological model that introduces the factors affecting the mental health of students. The results of an empirical study, which revealed the criteria for the formation of psychological health, are presented. The program on formation and preservation of mental health of students is developed.
Occupational hazards in anaesthesia and intensive care
Authors: Gubska О. Yu. , Rybak E. V.
Published: March 2023

The article is devoted to professional harmfulness arising among medical personnel (anesthetists and nurses) working in anesthesiology and intensive care units. Physiological, physical and chemical hazards in the work of medical staff, and as well the factors that contribute to occupational diseases considered in the article.
Children with depression and family
Authors: Iliadis Christos K. , Kourkouta Lambrini I. , Monios Alexandros G.
Published: March 2023

Depression is a psychiatric disease with a predominant symptom, emotional disturbance, physical annoyances and difficulties in interpersonal relationships. It can occur at any age, even in children. About 3 % of all children may experience depression. Depression as a disease affects the whole body and has an impact on how the child feels, thinks and behaves. These symptoms are accompanied by a number of other symptoms that affect appetite, sleep, levels of activity and concentration, children's self-confidence, and the image they have formed for themselves. Children with depression are usually sad and generally experience the disease in a similar way to older people.
Integrity as a factor of mental health in the context of the interdisciplinary problem of personal self-construction
Authors: Solomka T. M. , Shopshа O. L.
Published: March 2023

The urgency of the problem is due to terminological differences and differences in its interpretation, the lack of developed psychological theories and models, as well as contradictions existing within modern society. The purpose of the study is to provide theoretical substantiation of the structural and functional aspects of the phenomenon of integrity in contextually substantiated representations of mental health and the process of personal self-construction. As a research criterion, a synergistic approach is used that allows us to consider the integrity factor as an unstable universe that prepares a person to overcome crises and disasters with minimal losses. As a result of the analysis it was established: violation of the integrity (fragmentation) of the individual, which entails the propensity for the emergence of psychosomatic pathology, can be distinguished in a separate group of maladaptive states, border disorder and psychosomatic diseases with symptoms of bulimia, depression and alexithymia. By comparing the existing theoretical definitions of the violation of the integrity of the individual, it has been established that the destructive psychological mechanism is the fragmentation and insufficiency of regulatory activity, which ensures an active creative attitude to personal self-construction.The results of the research can be used in the development of educational and educational programs for psychologists, social workers, medical services and other professionals who, by the nature of their activities, contact with this category of persons.
Piritualization as factor of spiritual health of a person and society (in the context of the doctrine about biosphere and noosphere of V. I. Vernadsky)
Authors: Tyurina T. G. , Zachepa А. M.
Published: March 2023

The article considers issues of spiritual health of a person and society in the context of the doctrine about biosphere and noosphere of V. I. Vernadsky; close relationship and interaction between an individual’s spiritual health and the spiritual health of society, humanity, civilization, the planet is shown, because on the information-energy level they are the integral Cosmo-planetary system, active component of the Cosmo-planetary world.
Features of maintenance of mental health of teachers in ratings
Authors: Terentieva N. O. , Yashnyk S. V.
Published: March 2023

The aim of the paper is studying of factors of stress of lecturers in higher educational institutions of the country. Used a complex of general scientific theoretical methods, which correspond to the methodological and practical concepts of the pilot research, based on interrelated basis of such approaches as integral, systemic, synergetic, complex, activity approach, cultural-anthropological and others. Provided information about the ratings of the teaching staff of the universities where work authors of the publication. Ranking is presented as managerial innovation, which either supported or ignored by university lecturers. Some positions of ratings are as practically inachievable to teachers, others are real for being achieved for teachers with academic degrees as well as without ones. The activities of the teacher are considered as activities in special conditions that cause stress, conflict, psychosomatic manifestations, etc. Scientific activity is chosen because it certifies creating a new knowledge product, which is quite complicated and demanding intellectual and time resources, where 10 academic months are not enough to complete a textbook, a monograph, dissertation research, development of the state budget theme, etc. Social meaning: optimizing own activity is a key task of modern scientists, whose activities are foreseens a series of representative official scientific events.
Mental well-being and determination of adolescents’ inclination to deviant behavior (the modern Ukrainian experience)
Authors: Prokopovich E. М. , Krainikov E. V. , Traversay T. M.
Published: March 2023

The paper analyzed the medical and psychological characteristics of the determination of adolescents’ behavioral deviations, identified and described social psychological and personal factors that affect the dynamic indicators of deviant adolescents’ mental well-being, developed the psycho-corrective programs for deviant adolescents. The investigation found that significant factors underlying growth of adolescents’ deviant behavior and decline in mental well-being is due to their parents’ attitude towards the child’s growing up and greater independence, as well as non-constructive pedagogical position, the specifics of communication between teachers and pupils. Thus, a psycho-correctional program should include psychological work with the whole family, group personality-oriented psychotherapy and modification of the teaching and communication style in the dialogue between teachers and pupils.
Held in Suspense
Authors: Chatterjee Syantani , Chamorro Luciana , Montero Fernando
Published: March 2023

Promises of incorporation, threats of punishment, and fragile, revocable entitlements mark the signature of a modality of governance dedicated to the production of subjects who are neither included nor excluded from political or economic orders, but who are provisionally appended to them as though hanging by a thread. A wide array of political regimes renders these subjects simultaneously indispensable and expendable. The authors examine promise, threat and revocability as modalities of governance appearing across liberal and illiberal registers as a means to displace the costs, risks and responsibilities of political and economic projects onto the indeterminate subjects they simultaneously produce. The authors ask what subjects do as they are held in suspense, by studying the collectivities, social orders, and forms of political organisation that emerge amongst subjects as they anticipate the authorisations and the censures, the arrival and the forfeiture of governance.
Aane Wala Hai
Authors: Chatterjee Syantani
Published: March 2023

The Bharatiya Janata Party won the 2014 parliamentary elections in India, popularising the slogan ‘Achhe din aane wale hai’ (‘Good days are coming’). Even as the good days remained elusive, in 2019, the party won the popular vote again, with an additional promise of culling out putative ‘infiltrators’ from India by announcing ‘NRC aane wala hai’ (‘NRC is coming’). Drawing on ethnographic research carried out between 2016 and 2019 in a largely Muslim working-class neighbourhood next to one of Asia's largest garbage dumps in Mumbai, this article attempts to grasp the force of the state through its affective deferral by examining this aane wala hai form of governance – the forever-deferred, the always-arriving, the ready-to-strike – that is predicated upon weaponising deferral into a tactic of governance.
Waiting for Dignity Housing
Authors: Jonnalagadda Indivar
Published: March 2023

In this article, I track a housing scheme introduced in Hyderabad, India, to redevelop slums (in situ) into two-bedroom apartments. Drawing on ethnographic fieldwork, I argue that existing forms of governance cyclically enact a suspension of poor people's lives and often dispossess the poor of one set of rights in the process of delivering another set. In their own descriptions of these schemes, displaced communities emphatically account for the forms of suffering they repeatedly incur, which are unaccounted for in the records of the state. In their experience, governance is not only arbitrary and labyrinthine, but it also entails necessary experiences of dispossession that ironically accompany schemes for their development. This regime of dispossession that chronically underlies schemes for poverty alleviation is what I call ‘cruel governance’. Over time, this mode of development accompanied by dispossession has resulted in cynical realignments of subaltern politics towards the state and its projects.
John Chrysostom 'On the Incomprehensible Nature of God' – The Simpler Way of Presenting Complex Theological and Philosophical Issues
Authors: Kochańczyk-Bonińska Karolina
Published: March 2023

The purpose of this paper is to indicate how, that is, with the help of which means, Chrysostom in his five homilies “On the Incomprehensible Nature of God” introduces his community in Antioch to the intricacies of the dispute with the Anomoeans, as far as the possibility of knowing God and his essence are concerned. The main differences between those texts and other fundamental polemical sources with Eunomius will also be taken under consideration. John uses both biblical and philosophical terms to underline the negative aspect of theology and his five homilies are not so theologically and philosophically sophisticated as Basil’s or Gregory’s texts, unlike even Gregory of Nazianzus, whose Orations, have a similar overall message. John uses methods adequate to accomplish his goal, which is to preserve the orthodox concept and unify the Antiochian Church.
Investigating the Effectiveness of Ethics Programs in Promoting the Adoption and Implementation of Ethical Practices in Healthcare Organisations
Authors: Kiradoo Giriraj
Published: March 2023

Introduction: Ethics programs have become essential for healthcare organisations to adopt and implement ethical practices. Ethics in healthcare institutions is crucial to maintain trust and confidence in patients and stakeholders. Aims: This research paper aims to investigate the effectiveness of ethics programs in promoting the adoption and implementation of ethical practices in healthcare organisations. The study focuses on ten healthcare institutions and considers ethical practices as the dependent variable and implementation of ethics programs, organisational culture, employee training, leadership involvement, and regulatory compliance as independent variables. Method: The study uses a quantitative research approach, and data was collected through a structured questionnaire survey. Descriptive statistics were applied to summarise the data, while correlation analysis, regression analysis, ANOVA, and other statistical techniques were employed to analyse the relationships between the variables. The sample size was determined using the power analysis technique, and the data collected were analysed using statistical software. Results: The findings revealed a significant positive relationship between implementing ethics programs and ethical practices. The study also found a positive correlation between organisational culture, employee training, leadership involvement, regulatory compliance, and ethical practices. The regression analysis showed that implementing ethics programs was the most significant predictor of ethical practices in healthcare organisations. Conclusion: The study concludes that adopting and implementing ethics programs effectively promote ethical practices in healthcare organisations. Moreover, the study emphasises the importance of organisational culture, employee training, leadership involvement, and regulatory compliance in enhancing the effectiveness of ethics programs. The findings of this study can be employed as a guide by healthcare organisations to improve their ethical practices and ensure trust and confidence among patients and stakeholders.
Philippines. Economic and Social Activities of a Religious Institute: The Example of the Diocese of Butuan
Authors: Balabeykina Оlga A.
Published: March 2023

In the study, the authors consider the territorial and administrative structure of the Philippine’s Roman Catholic Church (RCC) and the factors of its transformation at the present stage in the context of the importance of the religious institution in the economic and social life of society. The purpose of a comprehensive study is to identify the economic, social, territorial and institutional aspects of the RCC’s activities in the Philippines and to identify the areas on which it has a significant impact. The model of relations between the RCC and the state in the Philippines is not typical for the Asia-Pacific region. This fact allows the authors stating that the experience of their implementation may be relevant for solving issues related to the formation and development of the confessional space of Russian regions, including the Far East, in social and economic aspects. For an objective characterization of the elements of the confessional space in the presented study the mathematical and statistical tools were used. By analyzing the available data published in English, the main directions of the project activities of non-profit Catholic organizations in the field of economic and social development of the country were identified. The authors reveal that the RCC actively implements activities in the field of social responsibility at the regional and local levels by allocating its own funds, labor resources, providing for the use of its buildings for religious and other purposes for organizing and holding socially significant events, in many ways contra-typing state functions. Finally, the authors conclude that the RCC in the Philippines is an influential institution that plays a significant role in various areas of the country’s economy and contains prospects for expanding the field of its activities in the mentioned direction
Hydrogeoecological conditions of technogenic groundwater in waste disposal sites
Authors: Semyachkov Aleksandr , Pochechun Viktoria , Semyachkov Konstantin
Published: March 2023

The specific hydrogeoecological conditions of aquifers of some technogenic formations, mainly iron ore skarn-magnetite and titanium-magnetite formations, are considered. The resulting wastes, which are stored in waste disposal sites during development of deposits, due to the impact of a number of factors (natural and technogenic) form technogenic waters. Waste disposal facilities are complex engineering structures (dumps and sludge storages), which in turn create their own hydrogeoecological conditions, which must be investigated in order to prevent and minimize environmental and economic damage caused by these objects to the aquatic environment. The paper presents long-term field and laboratory studies of the aquatic environment under the influence of a waste disposal facility in the Middle Urals – one of the largest tailings, representing a potential environmental and man-made hazard. This tailing dump contains tens of tons of waste – enrichment tailings and creates specific hydrogeoecological conditions on the territory. Based on many years of monitoring studies, an analysis of these conditions was carried out – the quality of groundwater affected by the tailings was assessed. It is shown that groundwater is of technogenic nature, i.e. are man-made waters that have a significant impact on the surface and underground hydrospheres of the territory.
The Roman Frontier with Persia in North-Eastern Mesopotamia
Authors: Anthony Comfort
Published: March 2023

The Roman frontier with Persia in north-eastern Mesopotamia investigates the Roman city of Singara and the fortifications and roads in the surrounding area. The physical frontier between Rome and Persia has been little studied, in part because of the difficulty of access for scholars. In comparison with other parts of the Roman ‘limes’, this frontier was of great importance because it separated the two major civilisations of the early first millennium CE. Although the frontier stretched north to Armenia and the Black Sea, north-east Mesopotamia was for long periods the major area of confrontation.

After a brief review of the history of north-east Mesopotamia and its role as the setting for repeated clashes between the two empires, the book focuses on Singara, its fortifications and the surrounding frontier zone. This town was one of the strongpoints on the Roman frontier as it existed up to 363 CE. The volume then addresses the ancient road network around Singara and the links to Nisibis and to the Khabur valley to the west. It makes use of old aerial photographs and satellite imagery to illustrate fortifications, roads and associated sites, in particular those mentioned in the Peutinger Table. A final chapter addresses the nature of the frontier in this region.
Persistent Pastoralism: Monuments and Settlements in the Archaeology of Dhofar
Authors: Joy McCorriston
Published: March 2023

A summary of archaeological teamwork along the Dhofar plateau and its backslope into the Nejd of Southern Oman, this book documents survey and excavation of small-scale stone monuments and pastoral settlements. Whether used as burial places, as landmarks, as mnemonic devices, or for other purposes, monuments are the enduring and prominent traces of desert pastoralists. In Dhofar, pastoralists constructed monuments in discrete pulses over 7500 years. Recognizing the dynamic ecosystems and climate regimes of Arabian prehistory, the author suggests that mobile pastoralists used monuments to link dispersed households into broader social communities. Furthermore, the range of practical adjustments to monuments as a consistent means of messaging among mobile people showcases the adaptive strength of Dhofar’s prehistoric inhabitants over time. A singular episode of settlement during a particularly arid period highlights the longer tradition of pastoral people on the move. With fictional vignettes to imagine the people who used these monuments, the chapters introduce archaeological analysis of the social identities, patterns of resource access, contacts, aversions, and exchanges with neighboring groups. Finally, the book underscores the rich heritage of persistent pastoralism within contemporary Oman.
DOĞU VE BATI TÜRKÇESİ ÖRNEKLEMİNDE -mAGXnCA VE -mAyIncA ZARF-FİİL EKİNDEKİ ŞART İFADESİ
Authors: KALEGERİ Çiğdem
Published: March 2023

Eski Türkçede -gınça/-gınçe ve seyrek olarak -kınça/-kinçe şeklindeki zarf-fiil eki, Doğu Türkçesinde -GInCA/-GUnCA ve Batı Türkçesinde -IncA/-UncA biçiminde devam etmiştir. Bu ekle kurulan zarf-fiiller ile temel tümcenin yüklemi arasında öncelik-sonralık, nedensellik, zaman bakımından sınırlandırma ve kimi zaman da şart ilişkisi kurmak mümkündür.

Bu ekin olumsuz kuruluşlarında ise Doğu Türkçesinde öncelik-sonralık ve şart, Batı Türkçesinde sınırlandırma ve şart ifadelerinin öne çıktığı görülmektedir. Bu zarf-fiil ekinin olumsuz biçimi, eklendiği fiilin gerçekleşip gerçekleşmemesine bağlı olarak tümcenin yükleminin bildirdiği hareket ya da oluşun gerçekleşip gerçekleşmeyeceğinin söz konusu olduğu durumları ifade etmektedir. Dolayısıyla bu ekle oluşturulan zarf-fiillerle bir şart anlamı da sağlanmaktadır.

Çalışmada elde edilen verilerden yola çıkarak Doğu Türkçesinde -mAGInCA/-mAGUnCA ve Batı Türkçesinde -mAyIncA biçimindeki bu olumsuz zarf-fiil ekinin hangi koşullarda şart ifade ettiği saptanmaya çalışılmıştır. Böylece şart ifadesinin iki lehçede farklılaşan gelişiminin belirlenmesi amaçlanmıştır.

Bu çalışmada, Eski Türkçedeki -gInçA/-kInçA ekinin olumsuz biçiminin Doğu ve Batı Türkçesindeki kullanımları için Gülistan ve Tezkîretü’l-Evliyâ’nın Farsçadan Doğu ve Batı Türkçesine yapılmış çevirileri taranmıştır. Söz konusu ekin olumsuz biçimleri belirlenerek anlam ve işlevleri, yüklemle ilişkileri ve bulundukları tümcelerdeki yüklemlerin özellikleri incelemeye tabi tutulmuştur. Doğu ve Batı Türkçesindeki aynı eserlerin seçilmesinin yapılacak karşılaştırmayı daha güvenilir kılacağı düşünülmüştür.
Automatic Chinese knowledge-based question answering by the MGBA-LSTM-CNN model
Authors: Liu Wenyuan , Fan Mingliang , Feng Kai , Guo Dingding
Published: March 2023

The purpose of knowledge-based question answering (KBQA) is to accurately answer the questions raised by users through knowledge triples. Traditional Chinese KBQA methods rely heavily on artificial features, resulting in unsatisfactory QA results. To solve the above problems, this paper divides Chinese KBQA into two parts: entity extraction and attribute mapping. In the entity extraction stage, the improved Bi-LSTM-CNN-CRF model is used to identify the entity of questions and the Levenshtein distance method is used to resolve the entity link error. In the attribute mapping stage, according to the characteristics of questions and candidate attributes, the MGBA-LSTM-CNN model is proposed to encode questions and candidate attributes from the semantic level and word level, respectively, and splice them into new semantic vectors. Finally, the cosine distance is used to measure the similarity of the two vectors to find candidate attributes most similar to questions. The experimental results show that the system achieves good results in the Chinese question and answer data set.
Identification of therapeutic targets and prognostic biomarkers among CXC chemokines in hepatocellular carcinoma microenvironment
Authors: Yin Zi , Ma Tingting , Chen Sheng , Yu Min
Published: March 2023

BACKGROUD: Hepatocellular carcinoma (HCC) is characterized by occult onset, rapid progression and poor prognosis. CXC chemokines play an important role in tumor microenvironment and development. OBJECTIVE: The potential mechanistic values of CXC chemokines as clinical biomarkers and therapeutic targets in HCC have not been fully clarified. METHODS: ONCOMINE, UALCAN, GEPIA, cBioPortal, SurvExpress, MethSurv, SurvivalMeth, String, GeneMANIA, DAVID, Metascape, TRRUST, LinkedOmics, and Timer were applied in this study. RESULTS: The transcriptional levels of CXCL9/16/17 in HCC tissues were significantly elevated while CXCL1/2/5/6/7/12/14 were significantly reduced. Significant correlation was found between the expression of CXC3/5 and the pathological stage of HCC patients. High level of CXCL4 was associated with a longer disease-free survival. For overall survival, lower expressions of CXCL1/3/5/8 and higher expressions of CXCL2 were associated with a better outcome. In addition, the prognostic values of CXC chemokines signature in HCC were explored in four independent cohorts, the high-risk group displayed unfavorable survival outcome compared with the low-risk group. And for the prognostic value of the DNA methylation of CXC chemokines, we identified the CpGs which were significantly associated with prognosis in HCC patients. DNA methylation signature analysis also showed a statistically significant association between the high- and low-risk groups. For potential mechanism, the neighbor gene networks, interaction analyses, functional enrichment analyses of CC chemokine receptors in HCC were performed, the transcription factor targets, kinase targets, and miRNA targets of CXC chemokines were also identified in HCC. We also found significant correlations among CXC chemokines expression and the infiltration of immune cells, the tumor infiltration levels among HCC with different somatic copy number alterations of these chemokine receptors were also assessed. Moreover, the Cox proportional hazard model showed that CCR2/6/8/12, B cell, macrophage and dendritic cell were significantly related to the clinical outcome of HCC patients. CONCLUSION: CXC chemokines might serve as therapeutic targets and prognostic biomarkers in HCC.
FHIR4FAIR: Leveraging FHIR in health data FAIRfication process: In the case of VODAN-A
Authors: Gebreslassie Tesfit Gebremeskel , van Reisen Mirjam , Amare Samson Yohannes , Taye Getu Tadele , Plug Ruduan
Published: March 2023

This article describes FHIR as a healthcare data exchange standard to attain the FAIR data principles taking the VODAN-A implementation as a showcase. FHIR relies upon the basic unit “resources” and the interaction among them. A new FAIR enabling architecture is proposed.
Feature optimization in CNN using MROA for disease classification
Authors: Mahajan Pranita , Rana Dipti
Published: March 2023

Electronic Medical Records (EMR) carry important information about a patient’s journey. The past decade shows substantial use of Natural Language Processing (NLP)-based Information Retrieval (IR) techniques to extract insights such as symptoms, diseases, and tests from these unstructured records. The state-of-the-art shows that convolutional neural networks (CNN) make a significant contribution to the disease classification task.A significant improvement in precise knowledge mining is possible with precise feature extraction. Feature selection addresses undesirable, unneeded, or irrelevant features. This article proposes a Modified Rider Optimization Algorithm (MROA) to choose important features by selecting optimal weights from a pool of randomly generated weights based on high accuracy and less training time in the CNN algorithm. A modified approach is trained on 114 N2C2 patients’ records to extract symptoms, disease, and tests are performed on them to perform disease classification tasks. The proposed approach is found to be accurate, with 97.77% accuracy in the disease classification and treatment prediction task from EMR.
Face presentation attack detection: Research opportunities and perspectives
Authors: Favorskaya Margarita N.
Published: March 2023

The rapid development of biometric methods and their implementation in practice has led to the widespread attacks called spoofing, which are purely biometric vulnerabilities, but are not used in conjunction with other IT security solutions. Although biometric recognition as a branch of computer science dates back to the 1960s, attacks on biometric systems have become more sophisticated since the 2010s due to great advances in pattern recognition. It should be noted that face recognition is the most attractive topic for deceiving recognition systems. Popular presentation attacks, such as print, replay and mask attacks, have demonstrated a high security risk for SOTA face recognition systems. Many Presentation Attack Detection (PAD) methods (also known as face anti-spoofing methods or countermeasures) have been proposed that can automatically detect and mitigate such targeted attacks. The article presents a systematic survey in face anti-spoofing with prognostic trends in this research area. A brief description of 16 outstanding previous surveys on the face PAD field is mentioned, from which it is possible to trace how this scientific topic has developed. SOTA in PAD provides an analysis of a wide range of the PAD methods, which are categorized into two unbalanced groups: digital (feature-based) and physical (sensor-based) methods. Generalization of deep learning methods as a recent trend aimed at improving recognition results requires special attention. This survey presents five types of generalization such as transfer learning, anomaly detection, few-shot and zero-shot learning, auxiliary supervision, and multi-spectral methods. A summary of over than 40 existing 2D/3D face spoofing databases is a guideline for those who want to select databases for experiments. One can also find a description of performance evaluation metrics and testing protocols. In addition, we discuss trends and perspectives in the emerging field of facial biometrics.
Naturally decision intelligence: Perfect algorithm generated by the hypothetical and synchronizing model for life system
Authors: Kaneko Tomoko
Published: March 2023

Decision Intelligence is a methodology that integrates complex systems, machine learning, and decision analysis. It is increasingly interested in finding optimal solutions to the uncertainties noted in machine learning in today’s complex AI systems. Furthermore, Decision Intelligence is a new engineering discipline that augments data science with theories from various sciences. Since decisions are made in all kinds of situations, they will become even more critical in a wide range of academic fields in the future. This paper introduces the ideas of proponents of Decision Intelligence, the promotion of digital decisioning toward automation, and trends in Western companies and Japan. Then, using risk management procedures, our examination of methods to ensure safety in the case of automated driving will be described. In addition, I will describe the challenges of each technology that promotes Decision Intelligence. I will also introduce a new synchronous AI that I am currently working on with the inventor of the challenge. This algorithm generation method is based on a metaphysical view of the synchronous nature of life activity.
Discrepancy Between Patient and Caregiver Estimate of Apathy Predicts Dementia in Patients with Amnestic Mild Cognitive Impairment
Authors: Grisanti Stefano Giuseppe ,   Dementia Disease Management Team3 of the IRCCS Ospedale Policlinico San Martino, Genoa: SchenoneAngelo NencioniAlessio AmoreMario BiffaGabriella SambucetiGianmario MorbelliSilvia RoccatagliataLuca CastellanLucio TravalcaCupillo Beatrice CastelliniPaola FioccaRoberto GaggeroGabriele MandichPaola OrigonePaola LivrariBarbara, Massa Federico , Chincarini Andrea , Pretta Stefano , Rissotto Roberto , Serrati Carlo , Monacelli Fiammetta , Serafini Gianluca , Calcagno Pietro , Brugnolo Andrea , Pardini Matteo , Nobili Flavio , Girtler Nicola
Published: March 2023

Background: Apathy is a frequent behavioral symptom of Alzheimer’s disease (AD). The Apathy Evaluation Scale (AES) is a tool exploring the perception of apathy by both caregivers (CG-AES) and patients (PT-AES), and the discrepancy in their ratings is a proxy of patients’ disease unawareness. Objective: To assess in a cohort study of patients with amnesic mild cognitive impairment (aMCI) whether apathy and awareness of apathy predict progression to dementia and timing. Methods: From the global AES scores of 110 patients with aMCI and their caregivers, we obtained two principal indices for analysis: 1) ‘Apathy’, the mean of PT-AES and CG-AES, and 2) ‘Discrepancy’, obtained by subtracting CG-AES from PT-AES. Patients were followed with visits every six months for three years or until dementia. AES indices and the principal demographical/neuropsychological variables were filtered from multicollinearity. The most robust variables entered a logistic regression model and survival analyses (Cox regression, log-rank test of Kaplan-Meier curves) to estimate which predicted the risk and timing of progression, respectively. Results: Sixty patients (54.5%) developed dementia (57 AD) after 6.0–36.0 months, 22 (20%) remained in an MCI stage, and 28 (25.5%) dropped out. ‘Discrepancy’ was a robust and accurate predictor of the risk of progression (AUC = 0.73) and, after binarization according to a computed cutoff, of timing to dementia. Conclusion: A structured evaluation of apathy, both self-assessed and estimated by caregivers, can provide useful information on the risk and timing of progression from aMCI to dementia. The discrepancy between the two estimates is a fairly reliable index for prediction purposes as a proxy of disease unawareness.
Low Ankle-Brachial Index Relates to Alzheimer-Signature Cerebral Glucose Metabolism in Cognitively Impaired Older Adults
Authors: Moon Seok Woo ,   and for the KBASE Research Group, Byun Min Soo , Yi Dahyun , Kim Min Jung , Jung Joon Hyung , Kong Nayeong , Jung Gijung , Ahn Hyejin , Lee Jun-Young , Kang Koung Mi , Sohn Chul-Ho , Kim Yu Kyeong , Lee Dong Young
Published: March 2023

Background: Ankle-brachial index (ABI), an indicator of atherosclerosis or arterial stiffness, has been associated with Alzheimer’s disease (AD) dementia and related cognitive impairment. Nevertheless, only limited information is available regarding its contribution to brain alterations leading to cognitive decline in late-life. Objective: We aimed to investigate the relationship of ABI with in vivo AD pathologies and cerebrovascular injury in cognitively impaired older adults. Methods: Total 127 cognitively impaired (70 mild cognitive impairment and 57 AD dementia) individuals, who participated in an ongoing prospective cohort study, were included. All participants underwent comprehensive clinical and neuropsychological assessment, ABI measurement, apolipoprotein E (APOE) ɛ4 genotyping, and multi-modal brain imaging including [11C] Pittsburgh Compound B (PiB)-positron emission tomography (PET) and [18F] fludeoxyglucose (FDG)-PET, and MRI. Results: General linear model analysis showed significant relationship between ABI strata (low ABI: <1.00, normal ABI: 1.00–1.29, and high ABI: ≥1.30) and AD-signature region cerebral glucose metabolism (AD-CM), even after controlling age, sex, clinical dementia rating–sum of box, and APOE ɛ4 positivity (p = 0.029). Post hoc comparison revealed that low ABI had significantly lower AD-CM than middle and high ABI, while no difference of AD-CM was found between middle and high ABI. There was no significant difference of global Aβ deposition, AD-signature region cortical thickness, and white matter hyperintensity volume between the three ABI strata. Conclusion: Our findings suggest that lower ABI, likely related to atherosclerosis, may contribute to the aggravation of AD-related regional neurodegeneration in cognitively impaired older adults.