bluuebunny/crossref_metadata_2025 huggingface dataset:
Practice-oriented training based on the pedagogical potential of traditional National Cultures
Authors:   East Siberian State Institute of Culture, Matveeva Elena V.
Published: May 2022

The article analyzes the problem faced by educational institutions today — ensuring optimal conditions for practice-oriented education in universities, including universities of the humanities. Aim this article was an appeal to the system of ethnic values that determines the content of educational technologies that take place in the educational process of various areas of training of a regional university of culture. Results. The optimally constructed model of practice-oriented education is based on the principles of preserving the traditional ethnic values of the peoples living in the territory included in the educational cluster. During the organization of practice-oriented training at the university, the leading principle of which is close interaction with the bearers of the values of ethnic culture of the peoples inhabiting Eastern Siberia, the cultural heritage is not only preserved, but also enriched due to the diversity of the ethno-cultural gene pool tested during the educational and educational activities of the university. In addition, the cultural heritage gets chances for further preservation and development The scientific novelty and practical significance of the undertaken research consists in the development of a special context of educational programs and the introduction of an ethno-cultural component into the curricula of most areas of training of a regional university of culture in order to provide a practice-oriented approach to the educational process and meaningful provision of the current stage of training for the cultural sector for the territory of Eastern Siberia.
The Russian National Museum Projects of as a form of National Ideology
Authors:   Voronezh State Technical University, Dorokhina Rimma V. , Marina Mariya V.
Published: May 2022

A national idea is understood in philosophy as a systematic generalization of national identity. The essence of national identity determines the existence of a people or ethnic group. There is currently no national idea in our country, although at every step we hear about patriotism. The first chapter of the modern Constitution of the Russian Federation which was adopted in 1993 recognizes ideological diversity. The text says: “No ideology can be established as state or mandatory.” For the lack of a national idea all programs of patriotic education do not lead to the formation of the ideal of a citizen and patriot. In the history of social thought in our country one can find many useful examples that could create a modern national idea as the state basis.
Specific gender aspect in the families of words
Authors:   Lobachevsky Nizhny Novgorod State University, Krupnova Natalia A. , Vlasova Karine A.
Published: May 2022

Much has been said and written about the gender aspect in linguistics. But there are still open questions concerning the specifics of the gender factor in word-forming nests. Therefore, we see the purpose of our research in the need to more accurately determine the presence and uniqueness of the semantic category of gender in the families of words with ‘young — old’ and their equivalents in the English and German languages. The article reveals various ways of expressing the meaning of the female and male genders, clarifies the problem of studying the gender aspect, and actualizes attention to the peculiarity of the gender factor in families of words. The analysis is based on three gender markers: morphological, lexical, and thematic. Each of these markers is considered on the example of lexical units identified by gender in the named word-forming nests. The morphological gender marker made it possible to identify gender-oriented lexemes formed by such methods of word production as conversion, suffix derivation, and word composition. The lexical marker determined the presence of five groups of words of different gender semantics. And, finally, using a thematic marker, gender formations associated with stereotypically ‘male’ and ‘female’ topics that take place in a certain period of development of society and the country as a whole were identified. Thus, as a result, it was proved that the ways of expressing semantic gender in the families of words under consideration are different and are due to both morphological and extra-linguistic reasons related to the specifics of the language picture of the world.
Armenian diaspora in Russia: Communicative and emotive picture of mi-grant’s world
Authors:   Peoples’ Friendship University of Russia, Anumyan Karpis S. , Harutyunyan Veronika N.
Published: May 2022

The article is devoted to the analysis of the emotional picture of the world of an Armenian migrant — an indispensable component of the individual’s overall world picture — in the receiving country. The research is conducted in the light of a new direction — at the junction of emotiology and linguomigratiology, two “young” interdisciplinary fields of the linguistic scientific thought — called emotive linguomigrationology. At the present stage of the development of these interdisciplinary studies conducted in the light of the anthropocentric scientific paradigm, there is a feeling person — homo sentiens — with all his/her experiences, sensations, feelings, and, of course, emotions. It is presumed that the processes that occur during communication do not differ significantly from the processes that take part in the functioning of language in general. And, as a rule, language contact is considered as a process of transmission and exchange of information, and in the definition of communication, along with the component of the exchange of thoughts, such components as relationships, mutual influences and interactions of people, their emotive / emotional empathy, the processes of achieving mutual understanding were identified. The empirical basis of this work was the results of an anonymous sociological survey conducted by the authors with the Armenians living in the Russian Federation. An anonymous survey among the representatives of the Armenian Diaspora in Russia was conducted during 2020–2021. The main purpose of the survey was to identify some ways of identifying the emotion of surprise in the migrant-oriented discourse. According to the results of an anonymous sociological survey, it is revealed that among the participants of the survey — the representatives of the Armenian diaspora in Russia — the emotion of surprise in the vast majority of cases is manifested by an indirect speech act, with the help of interjections ay, oh, ah, wow, etc.
Realization of the pragmatic potential of stylistic means of the Chinese language in the translation of V. Pelevin’s novel “Chapaev and the Void”
Authors:   Peoples' Friendship University of Russia, Korovina Svetlana G. , Li Jing
Published: May 2022

The aim of the research is to analyze stylistically marked means of the Chinese language from the point of view of the pragmatics of the postmodern literary text. Linguopragmatic analysis in this case is complicated by the fact that a translator is involved in the process of interaction between an author of the text and a reader. The duality of the function of a translator who is a native speaker of the Chinese language, who, on the one hand, is the addressee who perceives the text in a foreign language, and on the other hand, is a person reproducing a foreign language text in his native language, is aggravated by the specificity of the literary text. Any work of fiction and, in particular, the novel by V. Pelevin, has a number of functions, among which the most significant are the aesthetic, influencing, communicative. The translator, as a participant in the communication process, must as accurately as possible identify the intentions of the author of the novel, determine the linguistic means of the Russian and Chinese languages that most explicitly implement the above functions. The research studies some means of artistic expression of the Chinese language, which adequately reflect the pragmatic content of the Chinese-language translation of the novel: the paths and phraseological units of the Chinese language. At the same time, as a result of the analysis of the specifics of the translation of allusions, there is a decrease in the pragmatic function of the literary text in relation to the Chinese recipient.
About the significance of the recipient’s background knowledge factor for the comment text
Authors:   Neva Publishing House” LLC, Akulova Arina A.
Published: May 2022

The article is devoted to the problem of transferring background knowledge to the recipient of the text when composing the text of a commentary to a work of fiction; the need to translate not only referential, but also pragmatic and extralinguistic meanings of the text in the commentary is indicated. The transfer of extralinguistic — non-linguistic — components is an integral part of the modern practice of commenting when working with text. In linguistics, in relation to translated texts, this approach is called pragmatic, however, we emphasize that within the framework of this approach, we consider a commentary on a Russian-language foreign-cultural text, determine its function in the text. Special attention is paid to the typology of the commentary as a text from the standpoint of linguistic science. We believe that within the framework of the text-centric paradigm, we will analyze a kind of meta-texts “artistic text — commentary to it” (based on the well-known classification of intertextual and intratextual relations of J. Genette), we propose to consider them in chronological order.
НАПРЯМИ РЕАЛІЗАЦІЇ ДЕРЖАВНОЇ ПОЛІТИКИ РЕГІОНАЛЬНОГО ТА МІСЦЕВОГО ЕКОНОМІЧНОГО РОЗВИТКУ В УМОВАХ ДЕЦЕНТРАЛІЗАЦІЇ
Authors: Крайник О. П.
Published: May 2022

Метою дослідження є висвітлення сучасних підходів до реалізації державної політики регіонального економічного розвитку в умовах децентралізації, які базуються на усвідомленні значення розвитку кожного регіону, кожної територіальної громади, що забезпечує розвиток національної економіки загалом. Для отримання наукових результатів було використано декілька методів дослідження: економіко-статистичний метод (аналіз статистичних даних і відображення результатів аналізу); компаративний аналіз (порівняння стану економічного розвитку низки регіонів); абстрактно-логічний метод (формування пропозицій щодо активізації розвитку регіонів, формулювання висновків і пропозицій). Як результат дослідження проаналізовано темпи зростання основних показників регіонального економічного розвитку та зроблено висновок про вплив отриманих трендів на перспективи розвитку регіонів. Практичне значення отриманих результатів полягає у можливості врахування зроблених висновків у практичній діяльності органів державного та місцевого управління в активізації процесів регіонального та місцевого розвитку.
ДОСВІД ЕКСПОРТНО-ОРІЄНТОВАНОЇ ІНДУСТРІАЛІЗАЦІЇ АЗІЙСЬКИХ ТИГРІВ: ЧИ АКТУАЛЬНИЙ ВІН ДЛЯ СУЧАСНОЇ УКРАЇНИ?
Authors: Іванов Є. І.
Published: May 2022

У статті розглядаються проблеми використання економічної політики, механізмів та інструментів, які забезпечили випереджаюче економічне зростання азійських тигрів в останній третині минулого століття та привели їх до високого рівня життя на сучасному етапі. Автор ставить під сумнів функціональність цього досвіду в сучасному світі та має на меті оцінити доцільність реалізації політики експортно-орієнтованої індустріалізації в Україні. Проаналізовано обмежувальний характер сучасної багатосторонньої торгової системи у сфері тарифного захисту галузей-початківців. Обґрунтовано безперспективність спроб кардинального перегляду Україною ставок увізних мит для тимчасового захисту внутрішнього ринку. Окреслено інші зобов'язання в рамках СОТ, що обмежують державну підтримку трансферу інвестицій і технологій. Узагальнено положення міжнародного торгового права, що суттєво обмежують можливість експортного субсидування й використання інших нетарифних заходів для урядової підтримки виробництва на експорт. Виявлено радикальні зміни у структурі міжнародних економічних відносин, які суттєво знижують ефективність стратегії експортно-орієнтованої індустріалізації на сучасному етапі. Зокрема, встановлено, що уповільнення темпів зростання попиту з боку ключових глобальних споживачів за всеосяжної експансії пропозиції з боку Китаю ставить інші країни, націлені на експортно-орієнтоване зростання за азійським зразком, у настільки жорсткі конкурентні умови, у яких змагання за рахунок низької вартості робочої сили, субсидій та податкових пільг сягає крайньої межі доцільності використання цих чинників з огляду на збереження взаємозв’язку між економічним зростанням та підвищенням добробуту і рівня життя населення. Наголошено на вирішальному значенні регіонального лідера у наданні початкового поштовху до структурних зрушень у країнах, що розвиваються. На прикладі Південної Кореї та Тайваню розкрито, як Японія відіграла вирішальну роль у запуску випереджаючих темпів розвитку їхніх економік. У підсумку доведено, що послідовне копіювання Україною стратегії експортно- орієнтованої індустріалізації азійських тигрів не відповідає економічним реаліям та викликам сьогодення, натомість доцільним убачається використання окремих практик із відповідного досвіду.
РЕАЛІЗАЦІЯ СТРАТЕГІЇ РОЗВИТКУ ЦИФРОВІЗАЦІЇ ЕКОНОМІКИ УКРАЇНИ В УМОВАХ ІНДУСТРІЇ 4.0: МІЖНАРОДНИЙ ДОСВІД КРАЇН ЄС
Authors: Касяненко І. А. , Грінько І. М.
Published: May 2022

У статті досліджено забезпечення реалізації стратегії цифровізації економіки в умовах Індустрії 4.0, необхідність трансформації економіки у цифровий формат в умовах глобальних цифрових технологій. Процес переходу до Індустрії 4.0 передбачає трансформацію всіх сфер життя суспільства, у тому числі й економічних відносин. Розвиток цифрової економіки України лише починає набирати обертів, і важливо правильно вибрати напрями її реалізації. Також у статті розглядаються основні показники, пов’язані з цифровізацією. Проаналізовано стан розвитку цифрової економіки України на основі показників глобальних індексів за 2015–2020 рр. Проведено порівняльний аналіз цифровізації економіки деяких країн ЄС та України на основі експортно-імпортної діяльності та показників цифровізації. Здійснено порівняння напрямів реалізації стратегії цифрових економік країн ЄС, зокрема Німеччини, Франції, Швейцарії, для впровадження, адаптації деяких складників стратегій в економіку України. Запропоновано заходи для використання інноваційних технологій в умовах «цифрової ери» та стимулювання розвитку цифрової економіки України, які стануть каталізатором процесів цифровізації.
СТРАТЕГІЯ РОЗВИТКУ МІЖНАРОДНОЇ ДІЯЛЬНОСТІ ПІДПРИЄМСТВА ЦЕЛЮЛОЗНО-ПАПЕРОВОЇ ГАЛУЗІ УКРАЇНИ
Authors: Кузнєцова К. О. , Дергачова Г. М. , Байло О. О.
Published: May 2022

У статті поставлено за мету визначення стратегії розвитку міжнародної діяльності підприємства целюлозно-паперової галузі України на прикладі ТОВ «Український папір». Установлено, що на вітчизняному ринку функціонує близько 100 підприємств, які виробляють та перероблюють продукцію целюлозно-паперової галузі. Визначено, що діюча стратегія досліджуваного підприємства «ТОВ «Український папір» спрямована на ринок України і не забезпечує розвиток його міжнародної діяльності, а також є неефективною, що спричиняє зниження рівня доходів, фінансової стійкості та призвела до переходу підприємства у цикл спаду. Доцільним є вибір прийнятної стратегії: центрованої диверсифікації, конгломератної диверсифікації чи спільного підприємництва. Основною метою розвитку міжнародної діяльності ТОВ «Український папір» має стати максимізація прибутків.
“Breaking the Continuity” of the Latin American Vector of US Foreign Policy under Donald Trump and the Crisis of Pan-Americanism (2017-2020)
Authors: Eremin A.
Published: May 2022

In this article the author examines the process of revising the Latin American vector of US foreign policy under the presidency of Donald Trump. In particular, the paper analyzes the economic and political aspects of a new US policy in the Latin American region. The main focus of the research is on the reorganization of US economic relations with the countries of the region and cancellation of various financial aid programs and multilateral agreements, including the North American Free Trade Agreement. The main hypothesis of the paper is that US foreign policy under the 45th president underwent a profound change towards diminishing the role of the Latin American region among other foreign policy priorities of the United States. Vivid confrontation with China and the Russian Federation became the center of the contemporary foreign policy course of Washington, making relations with Latin American countries of secondary importance. This shift created a certain power vacuum in the region and opened additional opportunities for extraregional players. China could arguably become one of such players as it is known to have utilized Washington’s weakening grip on the region to its own economic and political benefit, expanding the “One belt, one road” initiative.
Renegosiasi Kontrak Sebagai Upaya Penyelesaian Pelaksanaan Kontrak Saat Pandemi Covid-19
Authors: Khoiri Harahap Syaiful
Published: May 2022

The COVID-19 pandemic proves the difficulties for business actors to operate their businesses, hence many of them face constraints in fulfilling their obligation to the creditors, which subsequently causes these debtors to be declared in default. Creditors as parties entitled to the fulfillment of the obligation are expected to understand the difficulties faced by debtors due to the COVID-19 pandemic. The problems raised in this study are: first, is the covid-19 pandemic may constitute ground for default by the debtor in fulfilling his contractual obligations, second, how are the efforts to resolve the obstacles in fulfillment of obligation in the covid-19 pandemic. This research was conducted using normative juridical methods and analyzed qualitatively. This study concludes that first, the covid-19 pandemic includes force majeure which resulted in the debtor experiencing economic difficulties to fulfill their obligation, leading to the debtor’s default which consequently resulted in the debtor losing his business and property which was used as collateral for debt repayment; second, if the debtor has difficulty in fulfilling their obligations, the debtor can ask the creditor to carry out renegotiation of the ongoing agreement based on the principle of kinship as mandated by Pancasila and the 1945 Constitution.
Pertanggungjawaban Pidana Korporasi Menurut Vicarious Liability Theory
Authors: Dwi Kurniawan Kukuh , Indri Hapsari Dwi Ratna
Published: May 2022

The development of the corporation is eventually positioning itself as an entity that gets stronger and more powerful due to its advantages over entities in the form of natural humans. These advantages can be realized through a combination of a group of people and assets that they can create a social impact around them. Corporations that have been sentenced to criminal penalty in the form of monetary fine create injustice as they consist of a collection of people from various duties and their respective functions, hence only a few people have the authority to determine the direction of the corporate policy, therefore the penalty in the form of fine are distributed to all sectors of the corporation to share the burden. This shows that the corporation management is the party responsible for corporate crimes. This study uses a normative juridical method by parsing the doctrine of vicarious liability. The results of this study conclude that to identify who is most responsible for the criminal acts of the corporation through the approach of Vicarious Liability Theory, it is the actually the management, where every action of the corporations falls within the authority and the will of the management, thus it is the corporate management which becomes the party most responsible for the criminal action committed by the corporation
Keadilan Pemilu Dalam Perkara Pidana Pemilu: Studi terhadap Putusan Pengadilan
Authors: Suparto Suparto , Heryansyah Despan
Published: May 2022

Electoral justice can be seen from at least two important aspects, namely the procedure of the election implementation and the mechanism for resolving election-related offences. Election-related offences are understood as actions that are contrary to the provisions of laws and regulations relating to elections. One of the said election-related offences is resolved through the District Court. However, reflecting on the completion of criminal acts in the 2019 legislative elections, electoral justice has not been successful. Of all the decisions of the District Courts in Yogyakarta and West Sumatra that have been analyzed, all of them issued probation to the perpetrator, regardless of the position of the perpetrator, the type of crime, and other aggravating reasons at trial. This study looks at the tendency of judges in deciding cases of election criminal violations and encourages the optimization of electoral justice in these decisions. This normative legal research emphasizes the use of secondary data, especially the decisions of District Court judges in Yogyakarta and West Sumatra. The results of the study show that first, the tendency of decisions to give very light sentences to perpetrators. Second, electoral justice has not been optimally obtained through the District Court because of the lightness of the sentence issued. This is because judges only consider the juridical aspect alone, without seeing the election as a real implementation of the sovereignty of the people as well as various other philosophical and sociological considerations.
Studi Komparatif Penyelesaian Sengketa Lingkungan Di Pengadilan Tata Usaha Negara Indonesia Dan Thailand
Authors: Romana Harjiyatni Francisca , Caroline Anthony Meicke
Published: May 2022

This study aims to analyze the comparison of environmental dispute resolution in the State Administrative Court (PTUN) of Indonesia and its Thailand equivalent. This is a normative legal research, using statutory and comparative approaches. The results of the study are presented in an analytical descriptive form. The results of the study conclude that first, the equatlisation for the settlement of environmental disputes in the Indonesian PTUN and the ones in Thailand is based on the General Administrative Court Procedure Law as regulated in the laws governing the PTUN of each country, but technical guidelines for resolving environmental disputes in the PTUN are issued by the respective Supreme Courts of each country. Second, the first difference is that the Thai Administrative Court provides special arrangements related to compensation issues which include costs for health problems, costs for damage to natural resources, loss of identity and community arts and culture. Meanwhile, the PTUN Indonesia provides very limited compensation and prioritizes the claim for the validity of the object of dispute. The second difference is that the handling of environmental problems in the Thai Administrative Court examines the substance and facts related to the environment more deeply, so that a real picture of environmental problems is obtained in the field. An in-depth study of the substance, facts, environmental problems in the field is taken into consideration by the judge in making a decision, even though administratively there are no problems. Meanwhile, the dispute resolution in the Indonesian PTUN is administrative and procedural in nature.
Why Does Inflammation Result in Resorptive Bone Loss?
Authors: Klein Gordon L.
Published: May 2022

Burn injury serves as an example of a condition with a robust inflammatory response. The elevation of circulating interleukins (IL)- 1 beta and -6 in children with severe burn injury up-regulate the parathyroid calcium sensing receptor (CaSR) resulting in hypocalcemic hypoparathyroidism with urinary calcium wasting. This effect protects the body from the hypercalcemia resulting from bone resorption liberating calcium into the circulation. Extracellular calcium can exacerbate and prolong the inflammatory response by stimulating mononuclear cell chemokine production as well as the NLRP3 inflammasome of the innate immune system, resulting in increased IL-1 production by monocytes and macrophages. Interestingly, the CaSR response to inflammatory cytokines disappears with age, potentially trapping calcium from bone resorption in the circulation and allowing it to contribute to increased inflammation and possibly increased calcium deposition in small arteries, , such as the coronaries, as conditions with increased chronic inflammation, such as spinal cord injury, osteoarthritis and rheumatoid arthritis have an incidence of cardiovascular disease and coronary artery calcium deposition significantly higher than the unaffected age-matched population.
Lateral Ulnar Collateral Ligament of the Elbow Joint
Authors: Fukai Atsuhiro , Nimura Akimoto , Tsutsumi Masahiro , Fujishiro Hitomi , Fujita Koji , Imatani Junya , Akita Keiichi
Published: May 2022

Background:

To improve the clinical results of lateral ulnar collateral ligament (LUCL) reconstruction of the elbow joint, better understanding of the anatomy of the aponeuroses and joint capsule could be relevant. This study considers the previously described anatomy of the LUCL in relation to the related aponeuroses and joint capsule rather than as a discrete ligament. We hypothesized that the deep aponeuroses of the superficial extensor muscles and supinator form a relevant portion of the joint capsule previously defined as the LUCL.

Methods:

Twenty-four elbows (12 right) from 21 embalmed cadavers (age at the time of death, 54 to 99 years) were included in the study. Twenty elbows were studied macroscopically and 4, histologically. The joint capsule was detached from the bones, and local thickness was quantitatively analyzed using micro-computed tomography (micro-CT).

Results:

The supinator aponeurosis and joint capsule intermingled to form a thick membrane (mean and standard deviation, 4.8 ± 1.2 mm), which we termed “the capsulo-aponeurotic membrane.” It was thicker than the anterior (1.3 ± 0.4 mm) and posterior (2.5 ± 0.9 mm) parts of the capsule of the humeroradial joint (p < 0.001). The capsulo-aponeurotic membrane had a wide attachment on the distal part of the extensor digitorum communis and extensor digiti minimi (EDC/EDM) origin of the humerus, the lateral part of the coronoid process, and the posterior part of the radial notch of the ulna. The humeral attachment had a fibrocartilaginous structure. The deep aponeuroses of the EDC and extensor carpi ulnaris (ECU) were connected to the capsulo-aponeurotic membrane.

Conclusions:

The capsulo-aponeurotic membrane was composed of the supinator aponeurosis and joint capsule and was attached to the lateral epicondyle of the humerus, radial side of the coronoid process, and posterior part of the radial notch on the ulna. The entire structure appeared identical to the commonly defined lateral collateral ligament. The most posterior part was connected to the EDC and ECU aponeuroses, which is commonly labeled the LUCL but does not exist as a discrete ligament.

Clinical Relevance:

Consideration of the accurate anatomy of the extensive attachment of the capsulo-aponeurotic membrane could provide useful clues for improvement in techniques of LUCL reconstruction and lateral epicondylitis pathology.
The Effects of Design Protection Legislation on Manufacturer Motivation
Authors: Blissick Megan E. , Orzada Belinda T.
Published: May 2022

This theoretical paper reviews the motivational factors of design protection legislation on knockoff manufacturing in the United States. Since at least the early 20th Century, U.S. apparel designers have requested design protection legislation. In fact, more than 90 attempts have been made to gain legal recognition and protection for original apparel designs through the U.S. legislative system since 1914. In France, however, from the time of Charles Frederick Worth, rules existed concerning what qualified as couture design, and over the following years, design protection in Europe evolved to continually protect creative design. In contrast, the United States continues to have limited design legislation that fails to protect fashion design. Parties in opposition to increased protection argue that legislation will stifle creativity, whereas parties in support counter that protection will encourage designers to create. This paper proposes the necessity of future research based on Tedmond Wong’s Innovative Design Protection and Piracy Prevention Act (IDPPPA) Game Theory Model to gauge the effect of design protection legislation on apparel manufacturer motivation to knock off designs. While this paper does not test the proposed research, it provides background supported by analysis and synthesis of current facts, data and research literature, and proposes directions of inquiry that may support design protection legislation.
Determination of Reasonable Bottom-Hole Pressure in Unconventional Tight Oil Reservoirs: A Field Case Investigation
Authors: Zhou Xiaofeng , Wei Jianguang , Zhang Ao , Zhang Xin , Rong Gen , Chen Yongda
Published: May 2022

The bottom-hole flow pressure is an important factor affecting the production of the unconventional tight oil well. The reasonable bottom-hole flow pressure has a positive effect on enhancing the production capacity of oilfields and improving the production efficiency of oilfield enterprises. Therefore, a robust method is proposed to determine the reasonable bottom-hole flow pressure in unconventional tight oil reservoirs, sharing the advantages of coupling geological feature and fluid flow behavior. In this method, the geological model and numerical reservoir simulation based on ECLIPSE software are developed firstly. The effects of the stress sensitivity, the PVT properties, permeability damage, fracturing fluid leak-off, and skin coefficient on the single-well productivity are then discussed. The reasonable variation range of the bottom-hole flow pressure in different production stages is then determined. Results show that crude oil viscosity, formation damage, and stress sensitivity are the most sensitive factors to the recovery degree. And, desirable tight oil production performance can be achieved with the application of the optimized bottom-hole pressure.
3D Nonlinear Analysis of Stilling Basin in Complex Fractured Dam Foundation
Authors: Meng Qingxiang , Wang Jian , Tao Zhigang , Ren Dazhong , Zhang Guangcheng , Li Xiaoshuang , Xie Liangfu
Published: May 2022

With the development of hydraulic engineering, more hydropower stations are built in the complex geological condition. This work proposed a case study on stilling basin in complex fractured dam foundation using 3D nonlinear analysis. A detail implementation of the numerical mesh generation from profile to solid geometry using boundary representation (B-Rep) is illustrated. Considering the main factors like self-weight, hydrodynamic pressure, and uplift pressure, the stress and deformation results of stilling basin in complex fractured foundation are obtained. According to the calculation and analysis, the design stilling basin can meet the engineering requirements of hydraulic structure. However, it is suggested to carry out the necessary foundation treatment for the sericitized slate as well as fracture plane. The study will provide valuable reference in the analysis of related engineering.
Elemental and Sr-Nd-Pb-Hf Isotope Signatures of Early Cretaceous Magmatic Rocks in the Wulian Area, Eastern Shandong: Implications for Crust-Mantle Interaction at the Edge of the Sulu Collisional Orogenic Belt
Authors: Du Qing , Meng Fanchao , Kerr Andrew C. , Chen Yong , Tian Yulu , Wu Zhiping , Zhou Yaoqi
Published: May 2022

We present new whole-rock geochemical, Sr-Nd-Pb isotopic, and zircon U-Pb and Hf isotopic data for Early Cretaceous magmatic rocks (trachy-andesite, pyroxene diorite, diorite porphyrite, and dolerite) in the Wulian area of Shandong, eastern North China. These data are used to constrain the mechanism of crust-mantle interaction at the edge of the Sulu orogenic belt. The belt formed by the collision of the Yangtze Craton (YC) and the North China Craton (NCC) during the Mesozoic. New zircon U-Pb dating indicates that the magmatic rocks were formed during the Early Cretaceous (123-124 Ma). These rocks are characterized by moderate contents of SiO2 (50.0-60.0 wt.%), MgO (3.3-5.6 wt.%), Cr and Ni with low Nb/U ratios (0.8-11.8), and high La/Nb (5.2-24.5) and Ba/La ratios (12.3-38.1). They are enriched in large ion lithophile elements, depleted in high field strength elements, and are characterized by high initial 87Sr/86Sr values (0.7079-0.7088) and low εNdt (-20.6 to -14.6). The samples have relatively low initial 206Pb/204Pb (16.38-17.18), 207Pb/204Pb (15.38-15.48), and 208Pb/204Pb (37.24-37.83) values. The Sr-Nd-Pb-Hf isotopic characteristics of the samples are similar to those of mafic rocks in the Sulu orogenic belt, suggesting that they might have similar sources. It is clear that the magma source of the samples involves both crustal and mantle materials and so we propose a model for crust-mantle interaction at the edge of Sulu orogenic belt. In this model, the Yangtze plate subducted deep below the northwestern NCC during the Triassic and was trapped in the lithospheric mantle. In the early Cretaceous, lithospheric extension in combination with asthenospheric upwelling resulted in partial melting of the overlying lithospheric mantle. The magmatic rocks in the Wulian area were generated by mixing between melts of both the lithospheric mantle of the NCC and the residual lower crust of the YC. This study therefore provides significant information on crust-mantle interaction at a continental subduction zone.
Effect of vaporizing cannabis rich in cannabidiol on cannabinoid levels in blood and on driving ability a randomized clinical trial
Authors: Egloff Laura , Frei Priska , Gerlach Kathrin , Mercer-Chalmers-Bender Katja , Scheurer Eva
Published: May 2022

Objective: To determine cannabinoid-levels in blood and driving-related ability after single (S1) and repetitive (S2) vapor inhalation of cannabis low in Δ9-tetrahydrocannabinol (THC), but high in cannabidiol (CBD). Methods: In a prospective, randomized, cross-over study at the Institute of Forensic Medicine Basel, healthy adults (NS1=27, NS2=20) vapor-inhaled two low-THC/CBD-rich products (both <1% THC), and placebo. Outcomes: i) THC- and CBD-levels in whole blood, ii) assessment of driving-related ability.Results: Among 74 participants included, 27 (mean age ± SD, 28.9 ± 12.5 years) completed S1, and 20 (25.2 ± 4.0) completed S2. THC dropped below 1.5 µg/L after 1.5 h, but was detected up to 5 h. Pairwise comparison of driving-related ability revealed no significant differences between low-THC/CBD-rich products (P1, P2) and placebo (P1 - P2: β = 0.319 [95% CI, -1.731 to 2.368], p = 0.950; P1 - placebo: β = 0.854 [95% CI, -1.329 to 3.037], p = 0.724; P2 - placebo: β = 0.535 [95% CI, -1.632 to 2.702], p = 0.879).Conclusions: Detection of THC after consumption of low-THC/CBD-rich cannabis might have legal consequences for drivers. Regarding overall driving-related ability, no significant differences were observed between interventional products.Trial Registration: German Clinical Trials Register: DRKS00018836.
Development and Application of Information Resources for Education and Teaching of Yarn History Based on 5G Network Technology
Authors: Yang Xiaoming
Published: May 2022

Yarn education is a crucial step in producing high-quality textile end products. Online yarn testing can reduce latency in necessary process control by providing rapid insights into yarn quality, leading to the production of superior quality yarns. This paper proposes the development and application of information resources for the education and teaching of yarn history based on fifth-generation (5G) network technologies. Initially, the yarn database is preprocessed using Grayscale transformation and image filtering methods. Secondly, yarn segmentation is implemented using a Multi-resolution Markov Random Field (MRMRF) model. The statistical and relative features are extracted using Fourier transform and two-scale attention model respectively. We propose Improved Support Vector Machine (ISVM) classification for classifying the yarn images. The 5G network is initialized and Transmission Control Protocol is used for data transfer. To enhance the performance we propose an Improved Particle Swarm Optimization (IPSO) algorithm. The performance of the suggested methodology is analyzed and compared with existing methodologies using the MATLAB simulation tool. The classification performance of the proposed algorithm indicates that the 5G framework might provide an accurate, fast, reliable, and cost-effective solution to industrial automation.
Antibacterial effect of kitchen herbs against pathogenic Multi Drug Resistant E. coli isolates from Calf Diarrhoea
Authors: Rai Saroj , Kumar M. , Jas R. , Mandal G.P. , Samanta I. , Rajendar M. , Tripura S. , Das S.K. , Mondal M. , Mandal D.K.
Published: May 2022

Calf diarrhoea remains the biggest challenge both in the small and large farms. Infectious diarrhoea is associated with many pathogens, E coli being one but, majority are systematically treated with antibiotics. Since antimicrobial resistance (AMR) is a growing menace, the need to find alternative prophylactic solutions using popular kitchen herbs such as Trachyspermum ammi (Carom seeds), Curcuma Longa (Turmeric) and Cinnamon (Cinnamomum sp.) extracts is been investigated against virulent form of E. coli isolated from calf diarrhoea. The virulence factors identified in these isolates were ST (32.5%), LT (20%), eaeA (15%), stx1 (2.5%) and stx2 (5%) with the occurrence of the most common serogroups as O18 (15%) followed by O111 (12.5%). Highest resistance was seen with β lactamase inhibitor (Amoxicillin/Clavalinic acid) followed by β lactams (Ampicillin, Cefuroxime and Cefepime). Antibacterial effect of cinnamon (methanol) and carom seed (ethanol) extracts was found to be highly sensitive at higher concentration of the extract (500 to 250 µg/ml) while, minimum inhibitory concentration (MIC) of turmeric was significantly higher (P<0.05) followed by cinnamon. Turmeric, cinnamon and carom had the potency of inhibiting the pathogenic E coli which maybe suggestive of its use in calf diets as prophylaxis against diarrhoea.
Photonically Active Bowtie Nanoassemblies with Chirality Continuum
Authors: Kotov Nicholas , Kumar Prashant , Vo Thi , Cha Minjeong , Visheratina Anastasia , Kim Ji-Young , Xu Wenqian , Schwartz Jonathan , Simon Alexander , Katz Daniel , Marino Emanuele , Choi Won Jin , Chen Si , Murray Christopher , Hovden Robert , Glotzer Sharon
Published: May 2022

Chirality is a geometrical property described by continuous mathematical functions.1–5 However, in chemical disciplines chirality is often treated as a binary left/right characteristic of molecules rather than a continuity of chiral shapes. While being theoretically possible, a family of stable chemical structures with the same shape and progressively tunable chirality is yet unknown. Here we present such structures in the form of nanostructured microparticles with anisotropic bowtie shape and widely tunable twist angle, pitch, size, thickness, and length. The self-limited assembly of the bowties enables high synthetic reproducibility, size monodispersity, and computational predictability of their geometries for different assembly conditions.6 The bowties nanoassemblies display multiple strong circular dichroism peaks originating from absorptive and scattering phenomena. Unlike classical chiral molecules, these particles display a continuum of chirality measures2 that correlate exponentially with the spectral positions of the circular dichroism peaks. Bowtie particles with variable polarization rotation were used to print photonically active metasurfaces with spectrally tunable positive/negative polarization signatures for light detection and ranging (LIDAR) devices.
Effectiveness of an Activity Package to Enhance Midwifery Clinical Leadership among Nursing Students: A Quasi-Experimental Study
Authors: Chooha Umasawan , Chotwattanakulchai Nadsuda , Duangsamran Duangduean , Sirisome Jirawun
Published: May 2022

Background: Current health crises have effects on maternal and child nursing. The healthcare system needs midwifery with good clinical leadership. The safety of mothers and infants is dependent on decisions made by midwifery to provide help if unexpected events occur. This quasi-experimental research was aimed at studying the effectiveness of an activity package for enhancing midwifery clinical leadership on nursing students.Methods: The quasi-experimental research with a one–group pretest–posttest design was conducted among Thirty undergraduate nursing students in fourth years were selected by randomly sampling and were allocated to one group. An activity package based on leadership skill approach theory. Data were collected before, immediately after, and six weeks after the intervention using “midwifery clinical leadership knowledge” “midwifery clinical leadership skills” and “satisfaction” Questionnaires. Data were analyzed using SPSS 22; Descriptive statistics, Paired t-test, and Analysis of Variances with Repeated Measures were used to analyze the data. Results: The mean score of midwifery clinical leadership knowledge in participants before the intervention was 9.56±1.52 that increased to 16.00±1.11 after the intervention (p<.001), midwifery clinical leadership skills before, immediately after, and 6 weeks after training, it was statistically significantly higher than before training at .05 and the trainees had maximum satisfaction with the training packageConclusion: Midwifery clinical leadership among nursing students increased in every area after training. Therefore, the promotion of midwifery clinical leadership among nursing students is essential. Supporting course activities can develop learning processes in nursing students while enhancing professional midwifery skills.
Flood risk identification using multicriteria spatial analysis. Case study: Gilort River between Bălcești and Bolbocești.
Authors: Giurea Alexandru-Andrei , COMĂNESCU Laura , DOBRE Robert , NEDELEA Alexandru , MIREA Ioana-Alexandra
Published: May 2022

Floods are the most widespread hazard globally and have a significant impact on local communities in terms of material and loss of life. Flood risk analysis is a complex process that needs to be addressed both physically and socially. The study provides a method for identifying the risk using Goegraphical Informational Systems techniques. Each indicator taken into account was analyzed, standardized and weighted to obtain the final results. The risk values have been divided into five classes: very low, low, medium, high and very high. The case study was represented by the River Gilort (a tributary to Jiu River), in a hilly area (Getic Sub Carpathians), between Bălcești and Bolbocești). Thus, the last two risk classes listed characterize the localities with the highest population density and which are situated near the river proximity. The results can also be used by the competent local authorities to effectively manage flood risk.
Prion protein conversion at two distinct cellular sites precedes fibrillisation
Authors: Ribes Juan , Patel Mitali , Halim Halim , Tooze Sharon , Kloehn Peter
Published: May 2022

The self-templating nature of prions plays a central role in prion pathogenesis and is associated with infectivity and transmissibility. Since propagation of proteopathic seeds has now been acknowledged a principal pathogenic process in many types of dementia, more insight into the molecular mechanism of prion replication is vital to delineate specific and common disease pathways. By employing highly discriminatory anti-PrP antibodies and conversion-tolerant PrP chimera, we here report that de novo PrP conversion and formation of fibril-like PrP aggregates are distinct in mechanistic and kinetic terms. De novo PrP conversion occurs within minutes after infection at two subcellular locations, while fibril-like PrP aggregates are formed exclusively at the plasma membrane, hours after infection. Phenotypically distinct pools of abnormal PrP at perinuclear sites and the plasma membrane show differences in N-terminal processing, aggregation state and amyloid formation and are linked by exocytic transport via synaptic and large-dense core vesicles.
Blood Cytology in Children with Down Syndrome
Authors: Puente Silvestre García de la , Arizmendi Karla Adney Flores , Tapia Yessica Yuliana Guerrero , Robledo Tania Tonantzin Vargas , Santiago Norma Candelaria López
Published: May 2022

IntroductionDown syndrome is associated with various congenital anomalies and metabolic alterations such as hematological alterations. Values for the major hematological indicators vary with age and sex, but these values have not been described for Mexican children with Down syndrome.Objective. To describe the complete blood count (CBC) values of pediatric patients with Down syndrome and report the most common non-malignant hematological alterations. Materials and Methods.The analysis includes data from 450 patients with Down syndrome, 55.5% ware males, aged 0-18 years who were patients at the Mexican National Institute of Pediatrics and whose clinical charts included CBC panel results for the period January 2008 through March 2018. Results.A total of 3438 CBC panels were analyzed with descriptive statistics to find the values and statistical dispersion of the major indicators, with percentiles, and reported separately by sex and age group. The most common non-malignant hematological alterations found were macrocytic anemia, leukopenia, lymphopenia, and thrombocytosis. There were differences in values in all three series.Conclusions. The CBC panels and hematological alterations are summarized for patients with Down syndrome.
The differentiation potential of human granulosa cells into sperm-like cells
Authors: Ghadirkhomi Elham , Maleki Masoud , ghadirkhomi Akram
Published: May 2022

Context: According to previous studies human-derived luteal phase granulosa cells are able to differentiate into other cell lineages, such as osteoblasts, chondrocytes and neurons. Aims: In this study we investigated the differentiation potential of these cells into sperm-like cells. Methods: First, we demonstrated the stemness of isolated GCs by flow cytometry and then we showed that granulosa cells can differentiate into advanced male germ cell lineages including spermatid-like cells in vitro. Follicular-phase GCs were cultured then induced by sheep testis tissue extract to differentiate into sperm-like cells, as evidenced by their expression of Gpr125, as well as VASA and DAZL, which are markers of different steps of Spermatogenesis.Key results: Mesenchymal stem cell markers were expressed in these cells. Spermatogenesis markers including DAZL,VASA and GPR125, were also expressed from the second week after induction. Morphological analysis of induced cells showed that Producing sperm- like cellsweresimilar to the normal sperm. Conclusions: Obtained results prove that isolated GCs are a kind of mesenchymal stem cells and have the capability to differentiate into sperm–like cells. Implications: This finding may represent a novel strategy for studying spermatogenesis in vitro or may help to improve assisted reproductive technology methods in the future.