bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence of Porcine Circoviruses in Slaughterhouses in Central Shanxi Province, China
Authors: Yue Weidong , Li Yilei , Zhang Xinrong , He Junping , Ma Haili
Published: May 2022

Background

Porcine circovirus disease is currently the greatest threat to pig farming. Four main porcine circovirus genotypes are circulating worldwide.

Objective

The study aimed to assess the prevalence of porcine circovirus genotypes in the central part of Shanxi province.

Methods

We investigated the prevalence of porcine circovirus type 2 (PCV2), porcine circovirus type 3 (PCV3), and porcine circovirus type 4 (PCV4). Porcine circoviruses were analyzed by polymerase chain reaction (PCR) in the lung tissues of 180 pigs from 7 slaughterhouses in central Shanxi, China.

Results

The prevalence of PCV2, PCV3, and PCV4 were 56.8, 80, and 9.4%, respectively, and the negative rate was 10% for all three pathogens. The co-infection with PCV2 + PCV3, PCV2 + PCV4, PCV3 + PCV4, and PCV2 + PCV3 + PCV4 were 47.2, 7.4, 7.4, and 5.6%, respectively. Among PCV4-positive samples, the positive rate of PCV4 + PCV2 was 52.9% (9/17), whereas that of PCV4 + PCV3 was 100% (17/17). On the other hand, PCV2 and PCV3 were detected in 57.1% (93/163) and in 78.5% (128/163) of PCV4-negative samples, respectively. Phylogenetic analysis demonstrated that PCV2, PCV3, and PCV4 were not in the same clade and were distant from each other.

Conclusion

The high positive rates of PCV3, PCV2 + PCV3, and PCV3 + PCV4 suggest that PCV3 may play a decisive role in PCV2 and PCV4 infections. Therefore, further control of PCV3 is needed to reduce the spread of the virus.
Retrospective Evaluation of Clinical Bleeding in Dogs With Anticoagulant Rodenticide Toxicity—A Multi-Center Evaluation of 62 Cases (2010–2020)
Authors: Stroope Sarah , Walton Rebecca , Mochel Jonathan Paul , Yuan Lingnan , Enders Brittany
Published: May 2022

Objective

To evaluate the most common locations of hemorrhage in dogs diagnosed with anticoagulant rodenticide intoxication.

Animals

Dogs presenting with hemorrhage secondary to anticoagulant rodenticide intoxication between at two university veterinary teaching hospitals.

Procedures

Medical records were searched from the years 2010 through 2020 and all records from dogs treated for hemorrhage secondary to anticoagulant rodenticide intoxication were reviewed. Dogs were diagnosed with anticoagulant rodenticide intoxication based on the combination of known exposure and prolonged coagulation testing, including prothrombin and activated thromboplastin time, or based on gas chromatography-mass spectrometry (GCMS). The diagnosis of hemorrhage was made based on physical exam findings, point-of-care ultrasound findings or radiography.

Results

Sixty-two dogs met the inclusion criteria and were included in the study. The most common sites of hemorrhage included: pleural space (hemothorax 37%), pulmonary parenchyma (24%), abdomen (24%), skin/subcutaneous (21%), gastrointestinal tract (18%), pericardium (13%), oral cavity (13%), nasal cavity (11%), ocular (8%), and urinary tract (7%). Overall, forty-five dogs (73%) had evidence of cutaneous or mucosal hemorrhage while thirty-three (53%) of dogs had evidence of cavitary hemorrhage. Forty-five percent of dogs had hemorrhage noted at only one site, while 55% experienced hemorrhage at more than one site. The location of hemorrhage and total number of hemorrhagic sites was not associated with survival or transfusion requirement.

Conclusions and Clinical Relevance

In conclusion, this study highlights that dogs with anticoagulant rodenticide intoxication present with diverse locations of hemorrhage and the majority of dogs had non-cavitary hemorrhage noted.
Wombat Roadkill Was Not Reduced by a Virtual Fence. Comment on Stannard et al. Can Virtual Fences Reduce Wombat Road Mortalities? Ecol. Eng. 2021, 172, 106414
Authors: Coulson Graeme , Bender Helena
Published: May 2022

The roadkill of wildlife is a global problem. Much has been written about deterring wildlife from roads, but, as of yet, there is no empirical support for deterrents based on visual and/or auditory signals. A recent paper entitled ‘Can virtual fences reduce wombat road mortalities?’reported the results of a roadkill mitigation trial. The authors installed a ‘virtual fence’ system produced by iPTE Traffic Solutions Ltd. (Graz, Austria) and evaluated its effectiveness for reducing roadkills of bare-nosed wombats (Vombatus ursinus) in southern Australia. The authors recorded roadkills in a simple Before-After-Control-Impact design but did not conduct any formal statistical analysis. They also measured three contextual variables (vegetation, wombat burrows, and vehicle velocity) but did not link these to the occurrence of roadkills in space and time. The authors concluded that the iPTE virtual fence system was ‘minimally effective’, yet ‘appears promising’. Our analysis of their data, using standard inferential statistics, showed no effect of the virtual fence on roadkills whatsoever. We conclude that the iPTE system was not effective for mitigating the roadkills of bare-nosed wombats.
Point-of-Care Wound Blotting with Alcian Blue Grading versus Fluorescence Imaging for Biofilm Detection and Predicting 90-Day Healing Outcomes
Authors: Wu Yu-Feng , Lin Yu-Chen , Yang Hung-Wei , Cheng Nai-Chen , Cheng Chao-Min
Published: May 2022

Biofilm infection has been identified as a crucial factor of the pathogenesis of chronic wound, but wound biofilm diagnosis remains as an unmet clinical need. We previously proposed a modified wound blotting technique using Alcian blue staining for biofilm detection that was characterized as being non-invasive, time-saving, non-expansive, and informative for biofilm distribution. In this study, we adapted a novel Alcian blue grading method as the severity of biofilm infection for the wound blotting technique and compared its biofilm detection efficacy with MolecuLight i:X- a point-of-care florescence imaging device to detect bacteria and biofilm in wounds. Moreover, their predictive value of complete wound healing at 90 days was analyzed. When validated with wound culture results in the 53 enrolled subjects with chronic wounds, the modified wound blotting method showed a strong association with wound culture, while MolecuLight i:X only exhibited a weak association. In predicting 90-day wound outcomes, the modified wound blotting method showed a strong association (Kendall’s tau value = 0.563, p < 0.001), and the wound culture showed a moderate association (Spearman’s rho = 0.535, p < 0.001), but MolecuLight i:X exhibited no significant association (p = 0.184). In this study, modified wound blotting with the Alcian blue grading method showed superior value to MolecuLight i:X both in biofilm detection and predictive validity in 90-day wound-healing outcomes.
Sensing Enhancement on Social Networks: The Role of Network Topology
Authors: Brede Markus , Romero-Moreno Guillermo
Published: May 2022

Sensing and processing information from dynamically changing environments is essential for the survival of animal collectives and the functioning of human society. In this context, previous work has shown that communication between networked agents with some preference towards adopting the majority opinion can enhance the quality of error-prone individual sensing from dynamic environments. In this paper, we compare the potential of different types of complex networks for such sensing enhancement. Numerical simulations on complex networks are complemented by a mean-field approach for limited connectivity that captures essential trends in dependencies. Our results show that, whilst bestowing advantages on a small group of agents, degree heterogeneity tends to impede overall sensing enhancement. In contrast, clustering and spatial structure play a more nuanced role depending on overall connectivity. We find that ring graphs exhibit superior enhancement for large connectivity and that random graphs outperform for small connectivity. Further exploring the role of clustering and path lengths in small-world models, we find that sensing enhancement tends to be boosted in the small-world regime.
Energy-Model and Life Cycle-Model for Grinding Processes of Limestone Products
Authors: Mannheim Viktoria , Kruszelnicka Weronika
Published: May 2022

Fine and ultrafine grinding of limestone are frequently used in the pharmaceutical, chemical, construction, food, and cosmetic industries, however, research investigations have not yet been published on the combination of energy and life cycle modeling. Therefore, the first aim of this research work was the examination of main grinding parameters of the limestone particles to determine an empiric energy-model. Dry and wet grinding experiments have been carried out with a Bond mill and a laboratory stirred ball mill. During the grinding processes, the grinding time and the filling ratio have been adjusted. The second goal of this research assessed the resources, emissions and environmental impacts of wet laboratory grinding with the help of life cycle assessment (LCA). The life cycle assessment was completed by applying the GaBi 8.0 (version: 10.5) software and the CML method. As a result of research, the determination of an empiric energy-model allowed to develop an estimated particle size distribution and a relationship between grinding fineness and specific grinding energy. The particle size distribution of ground materials can be exactly calculated by an empirical Rosin–Rammler function which represented well the function parameters on the mill characters. In accordance with LCA results, the environmental impacts for the mass of a useful product for different levels of specific energy with the building of approximation functions were determined. This research work sets up a new complex model with the help of mathematical equations between life cycle assessment and specific energy results, and so improves the energy and environmental efficiency of grinding systems. This research work facilitates the industry to make predictions for a production-scale plant using an LCA of pilot grinding processes.
Water Weakening of Artificially Fractured Chalk, Fracture Modification and Mineral Precipitation during Water Injection—An Experimental Study
Authors: Bredal Tine Vigdel , Korsnes Reidar Inge , Zimmermann Udo , Minde Mona Wetrhus , Madland Merete Vadla
Published: May 2022

This experiment was designed to study the water-weakening effect of artificially fractured chalk caused by the injection of different compositions of brines under reservoir conditions replicating giant hydrocarbon reservoirs at the Norwegian Continental Shelf (NCS). NaCl, synthetic seawater (SSW), and MgCl2, with same ionic strength, were used to flood triaxial cell tests for approximately two months. The chalk cores used in this experiment originate from the Mons basin, close to Obourg, Belgium (Saint Vast Formation, Upper Cretaceous). Three artificially fractured chalk cores had a drilled central hole parallel to the flooding direction to imitate fractured chalk with an aperture of 2.25 (±0.05) mm. Two additional unfractured cores from the same sample set were tested for comparison. The unfractured samples exposed a more rapid onset of the water-weakening effect than the artificially fractured samples, when surface active ions such as Ca2+, Mg2+ and SO42− were introduced. This instant increase was more prominent for SSW-flooded samples compared to MgCl2-flooded samples. The unfractured samples experienced axial strains of 1.12% and 1.49% caused by MgCl2 and SSW, respectively. The artificially fractured cores injected by MgCl2 and SSW exhibited a strain of 1.35% and 1.50%, while NaCl showed the least compaction, at 0.27%, as expected. Extrapolation of the creep curves suggested, however, that artificially fractured cores may show a weaker mechanical resilience than unfractured cores over time. The fracture aperture diameters were reduced by 84%, 76%, and 44% for the SSW, MgCl2, and NaCl tests, respectively. Permeable fractures are important for an effective oil production; however, constant modification through compaction, dissolution, and precipitation will complicate reservoir simulation models. An increased understanding of these processes can contribute to the smarter planning of fluid injection, which is a key factor for successful improved oil recovery. This is an approach to deciphering dynamic fracture behaviours.
A Critical Review of Alkaline Flooding: Mechanism, Hybrid Flooding Methods, Laboratory Work, Pilot Projects, and Field Applications
Authors: Khlaifat Abdelaziz L. , Dakhlallah Duaa , Sufyan Faraz
Published: May 2022

Over time, the dependence on oil has increased to meet industrial and domestic needs. Enhanced oil recovery (EOR) techniques in this regard have captured immense growth as EOR is not only used to increase the oil recovery but also to augment the sweep efficiency. Several techniques over the past decades have been used to improve oil recovery with cost-effectiveness. Cost-effective alkaline flooding has been effective for those oil reservoirs with a high total acid number. In this review, the significance of alkaline flooding has been discussed in detail, as well as the features of alkaline flooding in comparison to other modes of flooding. This review entails (1) alkaline flooding, (2) hybrid modes of injection, (3) experimental work, (4) pilot projects, (5) screening criteria, and (6) field applications. The findings of this study can help increase the understanding of alkaline flooding and provide a holistic view of the hybrid modes of flooding.
Profiles of Occupational Burnout in the Group of Representatives of High-Risk Professions in Poland
Authors: Makara-Studzińska Marta , Kruczek Agnieszka , Borzyszkowska Agata , Załuski Maciej , Adamczyk Katarzyna , Basińska Małgorzata Anna
Published: May 2022

(1) Background: Working in a high-risk profession is associated with taking on a large responsibility and risking loss of health or life. These professions include, among others, air traffic controllers, firefighters, and ECDs. People working in these professions are particularly vulnerable to experiencing high levels of stress and developing professional burnout syndrome. The aim of the conducted research was to assess the external and internal differences in the intensity of occupational burnout dimensions among representatives of high-risk occupations and to distinguish burnout profiles among them. (2) Methods: The total number of participants working in high–risk occupations who took part in the study was N = 1239, including the following job positions: air traffic controllers (n = 107), firefighters (n = 580), and ECDs (n = 558). The respondents completed the following self-report questionnaires: a structured survey and the Link Burnout Questionnaire. The following statistical tests were performed: cluster analysis, analysis of variance, and chi-square test of independence. (3) Results: The highest intensity of burnout dimensions was presented by representatives of ECDs. Profiles reflecting the types of occupational burnout were distinguished. The representatives of air traffic controllers demonstrated the following profiles: 1—low risk of burnout with a component of psychophysical exhaustion; 2—exhausted with a moderate tendency to disappointment; 3—burned out, ineffective, and uninvolved. The profiles of the ECDs were: 4—engaged, with a reduced sense of effectiveness; 5—with a reduced sense of effectiveness; 6—burned out with a low sense of effectiveness. However, the profiles of the firefighters were: 7—not burned out; 8—at risk of burnout; 9—exhausted with a tendency towards disappointment. Individuals representing the various burnout profiles differed in terms of the severity of the dimensions of occupational burnout as well as sociodemographic and work-related characteristics. (4) Conclusions: The process of occupational burnout varies among people in various high-risk occupations and due to sociodemographic characteristics. The internal differentiation of people representing high-risk professions requires different psychological interventions and preventive measures.
Anti-Inflammatory Effects of Psoralen Derivatives on RAW264.7 Cells via Regulation of the NF-κB and MAPK Signaling Pathways
Authors: Lee Yeji , Hyun Chang-Gu
Published: May 2022

Using repositioning to find new indications for existing functional substances has become a global target of research. The objective of this study is to investigate the anti-inflammatory potential of psoralen derivatives (5-hydroxypsoralen, 5-methoxypsoralen, 8-hydroxypsoralen, and 8-methoxypsoralen) in macrophages cells. The results indicated that most psoralen derivatives exhibited significantly inhibited prostaglandin E2 (PGE2) production, particularly for 8-hydroxypsoralen (xanthotoxol) in lipopolysaccharide (LPS)-stimulated macrophage RAW 264.7 cells. In addition, xanthotoxol treatment decreased the PGE2, IL-6, and IL-1β production caused by LPS stimulation in a concentration-dependent manner. Moreover, Western blot results showed that the protein levels of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), which activated with LPS treatment, were decreased by xanthotoxol treatment. Mechanistic studies revealed that xanthotoxol also suppressed LPS-stimulated phosphorylation of the inhibitor of κBα (IκBα), p38 mitogen-activated protein kinase (MAPK), and c-Jun N-terminal kinase (JNK) in RAW 264.7 cells. The Western blot assay results show that xanthotoxol suppresses LPS-induced p65 translocation from cytosol to the nucleus in RAW 264.7 cells. Moreover, we tested the potential application of xanthotoxol as a cosmetic material by performing human skin patch tests. In these tests, xanthotoxol did not induce any adverse reactions at a 100 μΜ concentration. These results demonstrate that xanthotoxol is a potential therapeutic agent for topical application that inhibits inflammation via the MAPK and NF-κB pathways.
Structural Basis for the Regiospecificity of a Lipase from Streptomyces sp. W007
Authors: Zhao Zexin , Chen Siyue , Xu Long , Cai Jun , Wang Jia , Wang Yonghua
Published: May 2022

The efficiency and accuracy of the synthesis of structural lipids are closely related to the regiospecificity of lipases. Understanding the structural mechanism of their regiospecificity contributes to the regiospecific redesign of lipases for meeting the technological innovation needs. Here, we used a thermostable lipase from Streptomyces sp. W007 (MAS1), which has been recently reported to show great potential in industry, to gain an insight into the structural basis of its regiospecificity by molecular modelling and mutagenesis experiments. The results indicated that increasing the steric hindrance of the site for binding a non-reactive carbonyl group of TAGs could transform the non-specific MAS1 to a α-specific lipase, such as the mutants G40E, G40F, G40Q, G40R, G40W, G40Y, N45Y, H108W and T237Y (PSI > 80). In addition, altering the local polarity of the site as well as the conformational stability of its composing residues could also impact the regiospecificity. Our present study could not only aid the rational design of the regiospecificity of lipases, but open avenues of exploration for further industrial applications of lipases.
Identification of Genomic Regions Associated with Vine Growth and Plant Height of Soybean
Authors: Lu Yipeng , Zhang Jiaming , Guo Xiaoyang , Chen Jingjing , Chang Ruzhen , Guan Rongxia , Qiu Lijuan
Published: May 2022

Vining growth (VG) and high plant height (PH) are the physiological traits of wild soybean that preclude their utilization for domesticated soybean breeding and improvement. To identify VG- and PH-related quantitative trait loci (QTLs) in different genetic resources, two populations of recombinant inbred lines (RILs) were developed by crossing a cultivated soybean, Zhonghuang39 (ZH39), with two wild soybean accessions, NY27-38 and NY36-87. Each line from the two crosses was evaluated for VG and PH. Three QTLs for VG and three for PH, detected in the ZH39 × NY27-38 population of the RILs, co-located on chromosomes 2, 17 and 19. The VG- and PH-related QTL in the ZH39 × NY36-87 population co-located on chromosome 19. A common QTL shared by the two populations was located on chromosome 19, suggesting that this major QTL was consistently selected for in different genetic backgrounds. The results suggest that different loci are involved in the domestication or adaptations of soybean of various genetic backgrounds. The molecular markers presented here would benefit the fine mapping and cloning of candidate genes underlying the VG and PH co-localized regions and thus facilitate the utilization of wild resources in breeding by avoiding undesirable traits.
Diethyl 2,5-Dihydroxy-3,6-diiodoterephthalate
Authors: Aitken R. Alan , Schindler Niti , Slawin Alexandra M. Z.
Published: May 2022

The title compound has been characterised for the first time by the full range of spectroscopic methods, and its X-ray structure shows hydrogen bonded stacks with iodine atoms aligned.
Structural Design and Application of Desensitized FBG Force-Measuring Bolt
Authors: Liang Minfu , Song Yang , Fang Xinqiu , Jiang Yuye , Zhang Fan , Li Shuang , Chen Ningning , Xu Ziyue
Published: May 2022

Bolt-supporting technology has been widely used in mine roadway support, and its own working conditions have important reference value for roadway safety support. In order to realize the continuous and reliable monitoring of the bolt rod’s working condition, this paper analyzes the existing problems of the existing fiber Bragg grating force-measuring bolt (FBG-FMB), and proposes a fiber grating strain desensitization sensing theory. Based on this theory, a desensitized FBG-FMB is developed with the spring as the elastic sensitive element. A mechanical analysis and drawing test show that the strain of the force-measuring bolt is greater than 60 times the micro-strain of the fiber grating, which verifies the feasibility of the structure design of the FBG-FMB. Finally, through the field application in the coal mine roadway, the working conditions of the bolt body at the two measuring points of the roadway are obtained to verify the reliability of the force-measuring bolt. In addition, the desensitized FBG-FMB can be widely used in the supporting fields of underground engineering such as slopes, tunnels, and foundation pits.
Dutch GPs’ views on prescribing mifepristone and misoprostol: a mixed-methods study
Authors: Schellekens Julia EAP , Houtvast Claire SE , Leusink Peter , Kleiverda Gunilla , Gomperts Rebecca
Published: May 2022

Background

The World Health Organization has indicated that GPs can safely and effectively provide mifepristone and misoprostol for medical termination of pregnancy (TOP). Dutch GPs are allowed to treat miscarriages with mifepristone and misoprostol, but few do so. Current Dutch abortion law prohibits GPs from prescribing these medications for medical TOP. Medical TOP is limited to the specialised settings of abortion clinics and hospitals. Recently, the House of Representatives debated shifting abortion to the domain of primary care, following the example of France and the Republic of Ireland. This would improve access to sexual and reproductive health care, and increase choices for women. Nevertheless, little is known about GPs’ willingness to provide medical TOP and miscarriage management.

Aim

To gain insight into Dutch GPs’ willingness to prescribe mifepristone and misoprostol for medical TOP and miscarriages, as well as the anticipated barriers.

Design and setting

Mixed-methods study among Dutch GPs.

Method

A questionnaire provided quantitative data that were analysed using descriptive methods. Thematic analyses were performed on qualitative data collected through in-depth interviews.

Results

The questionnaire was sent to 575 GPs; the response rate was 22.1% (n = 127). Of the responders, 84.3% (n = 107) were willing to prescribe mifepristone and misoprostol, with 58.3% (n = 74) willing to provide this medication for both medical TOP and miscarriage management. A total of 57.5% (n = 73) of participants indicated a need for training. The main barriers influencing participants’ willingness to provide medical TOP and miscarriage management were lack of experience, lack of knowledge, time constraints, and a restrictive abortion law.

Conclusion

Over 80.0% of responders were willing to prescribe mifepristone and misoprostol for medical TOP or miscarriages. Training, (online) education, and a revision of the abortion law are recommended.
Model Pertunjukan Ludruk Sinema: Wahana Pengembangan Ludruk Jawa Timur
Authors: Pudjastawa Astrid Wangsagirindra , Murti Bagus Baghaskoro Wisnu
Published: May 2022

There is a problem that underlies this researcher to do that, namely the interest of the younger generation in the art of ludruk is decreasing and it is feared that it will have an impact on the extinction of one of the various performing arts in Indonesia. This study aims to describe the ludruk cinema performance model, which is a new creative innovation offered to answer various problems of ludruk art. The learning method used is Design Thinking which consists of seven main stages, namely: (1) define, (2) research, (3) ideate, (4) prototype, (5) select, (6) implement and (7) learn. In the results and discussion section, the researcher describes (1) the concept of the Ludruk Cinema Performance, (2) the structure of the Ludruk Cinema Performance, and (3) the Ludruk Cinema Performance Model: A Forum for the Development of the Ludruk Cinema in East Java Cinema. The ludruk art development model is still strived to contain character values, with novelty carried out in the form of performances that are expected to be in accordance with the times.
Membaca Lukisan I Wayan Arnata melalui Kajian Semiotik Charles Sanders Peirce
Authors: Paramita Ni Wayan Satiani Pradnya
Published: May 2022

This article examines the paintings by I Wayan Arnata, a Balinese artist. I Wayan Arnata consistently explores spiritual themes, exploring the philosophy of life as embodied in the traditional ngJdi decoration technique. The purpose of this study is to examine the symbolic meaning of the work based on the semiotic theory of C.S. Peirce using qualitative descriptive research methods. Data were obtained through interviews with key informants: I Wayan Arnata (48 years old) and triangulated analysis with I Wayan Arnata's documents. The results of this study describe the nature of art for I Wayan Arnata and the concept of understanding Hindu-Balinese philosophy. The concept of the Tri Hita Karana philosophy, as the basis for understanding the creative process of harmony between humans and others, humans and the environment, and intrapersonal relationships with God. In his works, these spiritual values find a new space in I Wayan Arnata's interpretation of the expression of spiritual values expressed through visual language through formalistic aspects.
Pembelajaran Mural pada Mata Pelajaran Seni Budaya di Sekolah Menengah Atas Negeri 10 Malang
Authors: Hayati Farida
Published: May 2022

This article examines the emotional, intellectual, physical, aesthetic, artistic, and creative experiences of students at SMAN 10 Malang City. Students are directly involved in various creative experiences, producing works of art. Their real experiences directly benefit their lives. Learning mural art in the Cultural Arts subject allows students to interact with their technical abilities and environmental conditions. Murals are works of art that use drawing or painting techniques on permanent walls, walls or large surfaces. The purpose of this study is to examine the process of painting murals, considering that learning activities are believed to increase the intelligence of students, because the learning process involves cognitive, affective and psychomotor. The research method uses qualitative descriptive, the data used is student actions in the process of creating murals for class XII MIPA D students for the 2018-2019 school year. The analytical tools are observing, observing and recording student activities, as well as analyzing the work produced. The results of the study show that mural work is an alternative for teachers to increase students' creativity which is varied, namely 1) creative ideas, 2) reflection of students' emotional experiences, and 3) responsiveness to space.
Penciptaan Motif Batik Tulis Abstrak Gradasi dari Ragam Garis
Authors: Suasmiati Regreat
Published: May 2022

The art of batik culture in particular has existed since ancient times, and until now batik has developed and is a work of national culture. Batik is one of the cultural arts that is special, namely a combination of art and technology, is a work of art that combines the art of motifs or decoration and color art which is processed through dyeing, dabbing and shaving (Sewan, 1982). This study aims to show that Variety of Lines can generate new ideas in the presentation of batik motifs. The emergence of new patterns according to local cultural wisdom is unique in strengthening the nation's identity as a world cultural heritage. Seeing the good prospects of the development of the art of batik, it is necessary to pay attention to basic things such as quality, basic materials (fabric, dyes, etc.), the workmanship system and the development of ideas in its presentation so as to provide economic value and have a long-term positive impact on the art of batik itself. Variety of Lines can be used as an idea to bring up new motifs. The results of this study indicate that the Variety of Lines can generate new ideas in the presentation of batik motifs and also helps to flex the use of canting in the written batik technique.
Alterações de equilíbrio e risco de quedas em idosos com vertigem posicional paroxística benigna: uma revisão integrativa
Authors: Guedes da Paz Erivânia , Mendes Daiana de Jesus da Silva , Oliveira Thaise Cristina Lima de , Barbosa Wilames Oliveira
Published: May 2022

Introdução. A vertigem posicional paroxística benigna (VPPB) corresponde a distúrbios que ocorrem na orelha interna, cujo resultado é uma sensação giratória transitória acompanhada ou não de nistagmo. Objetivo. Analisar como as implicações das alterações de equilíbrio influenciam no risco de quedas em idosos com vertigem posicional paroxística benigna.  Método. Trata-se de uma revisão integrativa da literatura. Os dados referem-se ao período de 2011 a 2021 e foram coletados nas bases de dados cientificas PubMed, Scielo, BVS e Cochrane. Foram incluídos estudos de língua inglesa, espanhola e portuguesa. Resultados. A busca resultou em 339 artigos, no qual 206 foram excluídos por duplicação. Após leitura na integra seis artigos foram incluídos para composição da revisão. Conclusão. É possível afirmar que o aumento na dependência visual, o desequilíbrio corporal e o risco de quedas são achados em pacientes com VPPB e implicam em diminuição da qualidade de vida de pacientes idosos.
Learning Methodological Lessons from Exemplar Studies in Nephrology: PEXIVAS and Sample Size Calculation
Authors: Sandys Vicki , Sexton Donal J.
Published: May 2022

Key Learning Points

Sample size calculations are fundamental to the power of a study. Estimates of the necessary sample size to achieve a given treatment effect size can be performed pre-trial based on available literature.

Sample size calculations take into account the chosen effect size i.e. the minimal effect of the treatment which would be considered clinically relevant. Smaller effect sizes require a sufficiently large sample size or higher event rate to detect differences between groups. Larger effect sizes are sometimes chosen for study in order to justify the risks of adverse events and expense of certain treatments.

Lower than expected event rates, mediated by censoring and competing risks, period effects, and inclusion of patients at lower risk of the outcome, can impact the power of the study.

Time-to-event study designs adjust for censoring and competing risks.

If a lower than expected event rate is highlighted during an interim analysis, strategies include increasing the sample size, either by changing the inclusion or exclusion criteria, increasing the number of study centers or increasing the study duration.
USO DE CONTEINERS NA CONTRUÇÃO CIVIL
Authors: José Benvindo Mazini Mateus
Published: May 2022

The area of civil engineering is in continuously growing and news technologies of construction to suggest to increase efficiency and economy. Therefore, in that thought that construction using containers introduce yourself more advantageous, for besides offer these advantages, since it has an ecologically sustainable material. This technique is little used in our country, on the other hand, reuse this material that could be destined for inappropriate disposal in nature, and also, reduces the amount of raw material in all stages of the work. Thus, this article intends to demonstrate the potential of this material, as a constructive method, which enables greater viability when compared to traditional housing methods, to proving the applicability and advantages of containers in civil construction. This work was founded your research study based on bibliographic data, demonstrating some situations and advantages where this type of material was implemented in construction. This way it was possible to conclude that despite being a quick way, clean and sustainable, the method needs to be more widespread so that people can use it properly.
OS DESAFIOS DO ENSINO APRENDIZAGEM NA MODALIDADE EAD PARA ALUNOS COM TDAH
Authors: FERREIRA PAIS FILHO ESTEVAM , Ferreira dos Santos Júnior Benedito , da Costa Tavares Okuyama Claudete
Published: May 2022

Among the various global disorders of human development that can significantly influence the teaching-learning process at school, there is Attention Deficit Disorder with Hyperactivity - ADHD, which, due to its characteristics, brings a series of challenges to the student. The present work aimed to identify the main challenges of teaching and learning in the e-learning modality faced by students with ADHD. For this, a literature review was carried out with all its steps. As a result, 67 studies were analyzed, of which 30 were considered, including articles, books, legislation, blogs, monographs and TCC. It was concluded that, in addition to the challenges that are common with face-to-face teaching, e-learning also brings: training for parents and teachers to deal with technology and help students; development of effective teaching methods and provision of companions for these students during classes.
GROWTH RESPONSE AND PRODUCTION OF TWO VARIETIES OF OKRA (Abelmoschus esculantus L. Moench) ON GIVING VARIOUS TYPES OF ORGANIC FERTILIZER
Authors: Barus Ria Anindi Antika
Published: May 2022

Okra is a vegetable plant that can be consumed directly or made into processed foods and has good pharmacological effects in the health sector. Okra has a high economic value when compared to other vegetables. The problem faced in okra cultivation is that this plant is not well known by the Indonesian people. The application of organic fertilizer to okra cultivation is expected to improve quality and quantity. This research was carried out on community land for the construction of the Medan Selayang sub-district with an altitude of ± 25 meters above sea level. This research was conducted from May to September 2016, using a randomized block design with 2 treatment factors. The first factor is varieties with 2 types, namely burgundy red okra and Garibar green okra and the second factor is the application of organic fertilizer with 4 types, namely without organic fertilizer, compost, vermicompost fertilizer, and chicken manure. The results showed that the varietal treatments were significantly different on plant height 10-14 WAP, flowering age, number of fruit per plant, fruit weight per plant, number of fruit per plot, fruit length, fruit diameter and canopy wet weight. The application of various kinds of organic fertilizers significantly affected the parameters of plant height increase 10-14 WAP, number of leaves 10-14 WAP, flowering age, number of fruit per plant, fruit weight per plant, and number of fruit per plot. The interaction between varietal treatment and the application of various kinds of organic fertilizers had a significant effect on the increase in plant height 10-14 WAP.
GROWTH RESPONSE OF ROBUSTA COFFEE (Coffea robusta L.) GROWTH ON CHICKEN CAGE FERTILIZER AND FERTILIZER LIQUID ORGANIC
Authors: Lubis Ahmad Ridwan
Published: May 2022

The purpose of this research is to know the response of robustacoffee seedling from the application of chicken manure and liquid organic fertilize. This research was held in land that are on Kecamatan Medan Johor road, North Sumatra with altitude ±32 meters above the sea level, started from May until September 2016. This research was using factorial randomized block design with 2 factors. The first factor is the application of chicken manure (topsoil:manure)with four levels, namely: (1:0); (3:1); (2:1); (1:1) and the application of liquid organic fertilizer with four levels of 0 cc/l; 2 cc/l; 4 cc/l; 6 cc/l. The observed parameters were plant height (cm), stem diameter (mm), root volume (cm3), totalleaf area (cm2), dry weight of root (g), dry weight of shoot (g), and shoot-root ratio. The result showed that chicken manure treatment significantly increased the plant height, stem diameter, root volume, total leaf area, dry weight of root, dry weight of root and shoot-root ratio. The application of liquid organic fertilizer significantly increased the total leaf area parameter. The interaction between both treatments significantly increased dry weight of root, dry weight of shoot and total leaf area parameters.
ANALYSIS OF GENETIC DIVERSITY OF PALM OIL PLANT (Elaeis guineensis Jacq.) PALM OIL RESEARCH CENTER (PPKS) BASED ON PRIMARY SSR (Simple Sequence Repeats)
Authors: Aulia Riski
Published: May 2022

The background of this research was to obtain information of genetic diversity within and among populations of E. guineensis using SSR markers. This research was conduted in Biology Molecular Laboratory, Indonesian Oil Palm Research Institute, Marihat, Pematangsiantar, North Sumatra from March 2016 to January 2017. A total of 100 palm oil samples used in this research, including 20 samples from the populations of E. guineensis TR01S, including 20 samples from the populations of E. guineensis BJ022S, including 20 samples from the populations of E. guineensis BJ42S, including 20 samples from the populations of E. guineensis BO52S, and including 20 samples from the populations of E. guineensis MA19S. Calculation and Desciptive analysis in this research using software GeneMarker® version 2.40, software DARwin version 6.0.13 and Microsoft Excel 2007. Research shows that the number of banding patterns detected 104 The banding patterns WITH range 8-9 per primary banding pattern, and the size of the banding patterns ranging from 101 bp -328 bp. mEgCIR2569 primary is the most widely primer to amplify DNA and the average of the percentage of polymorphism in the primer being used by 71%. Analysis dendogram 100 samples All 3 hearts big group of Jatropha genetic WITH BETWEEN Yang ranged from 0.03 to 1.00 Based on the findings of the analysis of genetic relationships WITH Matrix Method using differences Simple Matching Value factorial analysis (PCoA) declared WITH axis I and axis II ON 12 primary SSR of 20.3%. mEgCIR2569 primary is the most widely primer to amplify DNA and the average of the percentage of polymorphism in the primer being used by 71%. Analysis dendogram 100 samples All 3 hearts big group of Jatropha genetic WITH BETWEEN Yang ranged from 0.03 to 1.00 Based on the findings of the analysis of genetic relationships WITH Matrix Method using differences Simple Matching Value factorial analysis (PCoA) declared WITH axis I and axis II ON 12 primary SSR of 20.3%. mEgCIR2569 primary is the most widely primer to amplify DNA and the average of the percentage of polymorphism in the primer being used by 71%. Analysis dendogram 100 samples All 3 hearts big group of Jatropha genetic WITH BETWEEN Yang ranged from 0.03 to 1.00 Based on the findings of the analysis of genetic relationships WITH Matrix Method using differences Simple Matching Value factorial analysis (PCoA) declared WITH axis I and axis II ON 12 primary SSR of 20.3%.
THE EFFECT OF BIOCHAR APPLICATIONS OF RICE HUSK AND COFFEE SKIN ON P AND Zn NUTRITIONS AND THE GROWTH OF RICE (Oryza sativa L.) PLANTS IN SATISFIED RICE LAND
Authors: Naibaho Satber
Published: May 2022

This study aims to evaluate the effect of rice husk and coffee husk biochar, evaluate difference effect of rice and coffee husk biochar and to know the effect of difference of dose of rice and coffee husk biochar phosphate and zinc, and rice growth in the paddys soil with high total P . The research was conducted on the greenhouse, Faculty of Agriculture, University of North Sumatra, Medan. The soil which used from the paddys soil in Lubuk Dendang, Perbaungan, Serdang Bedagai which has the high total P. The experiment was carried out using completely randomized design with 7 treatment : control ; 10 tons/ha, 20 tons/ha, and 30 tons/ha rice husk biochar ; 10 tons/ha, 20 tons/ha, and 30 tons/ha coffee husk biochar. The Analysis of data used the analysis of variance and contrast orthogonal test.
FORECASTING ANALYSIS OF CHICKEN MEAT PRODUCTION AND CONSUMPTION (BROILER) IN NORTH SUMATRA PROVINCE
Authors: Hardian Febry
Published: May 2022

This study aims to analyze the production and consumption of broiler meat in North Sumatra Province with forecasting analysis using the SPSS program application. The method of determining the area used is purposive area sampling. The data used in this study are secondary data obtained from the Central Statistics Agency and the Department of Animal Husbandry and Food Security, North Sumatra Province. The results showed that in 2006-2015 in North Sumatra Province, broiler chicken meat production experienced a positive trend and for broiler chicken meat consumption also experienced a positive trend. In 2006-2015 in North Sumatra Province, broiler meat consumption was greater than broiler meat production in North Sumatra Province. For the years 2016-2025 in North Sumatra Province, it shows that the results of forecasting analysis of broiler meat production have a negative trend and the results of forecasting analysis of broiler meat consumption experience a negative trend which decreases with not too significant differences between the results of forecasting analysis of chicken meat production and consumption. broilers in North Sumatra Province.
The Results of the SWOT Analysis Approach in Formulating Company Strategy at the American English Course Purwokerto
Authors: Surveyandini Mayla
Published: May 2022

This research is entitled "The results of the SWOT analysis approach in formulating company strategy at the american english course purwokerto". The purpose of this study is to determine and measure the company's strengths (Strength), company weaknesses (Weakness), analyze opportunities (Opportunities) and threats (Threats) at the American English Course Purwokerto. This research is a descriptive qualitative research by collecting information about research subjects and the behavior of research subjects in a certain period. Data processing is carried out with a SWOT analysis process as a strategy formulation tool. The SWOT analysis that has been formed is then formulated in the form of a SWOT matrix with 4 (four) strategic formulas, namely SO Strategy, WO Strategy, ST Strategy and WT Strategy. The results of the study show that the American English Course is a business engaged in services. An effective and optimal planning strategy is needed that covers all aspects from planning to marketing. Quality products, optimal services supported by the right infrastructure including promotional activities will certainly bring success to the company's progress. Customer satisfaction is the key that must be prioritized to seize market share that is increasingly growing and competitive. The findings in this study have several important implications for the company to further improve and improve strategies both in terms of planning and marketing, namely the need to improve product quality and human resources, improve service and creativity to consumers so that consumers do not move to other competitors, use technological developments as learning and promotion facilities.
CENTER OF PALLIATIVE MEDICINE AT KHARKIV NATIONAL MEDICAL UNIVERSITY: MODERN CHALLENGES AND DEVELOPMENT STRATEGIES
Authors: Kapustnyk Valeriy , Myasoedov Valeriy , Riga Olena , Orlova Natalia
Published: May 2022

In most countries of the world, palliative care is an integral part of quality medical care, which includes comprehensive medical, social, psychological, and spiritual support for critically ill patients and their relatives. According to the WHO, every year about 20 million people worldwide need palliative care at the end of their lives. There are many more who need palliative care until the last year of their lives. Thus, the total number of people who need palliative care annually is about 40 million. It is estimated that of the 20 million people in need of end-of-life palliative care, 78% live in low- and middle-income countries; about 67% are elderly and about 6% are children. However, only 14% of people who need end-of-life palliative care receive it. Palliative care considers the principle of respect for patients' decisions and aims to provide practical support to their family members during illness and in the event of a patient's death to overcome grief over the loss of a loved one. The WHO's global strategy for health care, based on human approach and integration, is to strengthen palliative care programs for patients with various diseases. Despite the fact that some steps have already been taken in Ukraine towards the development of palliative care, there are still some problems: lack of qualified medical staff; lack of relationships between primary and secondary, tertiary care and coordination; imperfect system of informing medical workers about ensuring the right to anesthesia for seriously ill patients; lack of a sufficient number of pharmacies licensed to operate controlled medicines; lack of interagency programs in the field of palliative care.
INFLUENCE OF INSULIN-LIKE GROWTH FACTOR-I LEVELS ON THE COURSE OF ACUTE MYOCARDIAL INFARCTION: review
Authors: Kapustnik Valeryi , Martovytskyi Dmytro , Shelest Boris , Shelest Olexiy , Ponomarenko Fedir
Published: May 2022

Over the last many years, cardiovascular disease has reached epidemic proportions among chronic noncommunicable diseases worldwide. According to the latest tendencies, cardiovascular diseases play the leading role in the formation of current negative health and demographic trends in Ukraine and all over the world: they significantly affect the main health indicators: morbidity, mortality, disability, life expectancy and quality of life. If we take the last 20 years, we can see that the prevalence of CVDs among the Ukrainian population has tripled, and the mortality rate from them has risen by 40%. Review was analysed serum level insulin-like growth factor-I (IGF-I) in patients with acute myocardial infarction and his role in left ventricular remodelling was established. The scientific data regarding the neurohumoral component of acute myocardial infarction pathogenesis have been expanded by increasing levels of the angiogenesis marker IGF-I, which can be explained by his properties as markers of the acute phase of inflammation. An analysis of the relationship between troponin I and IGF-I, a marker of myocardial damage, showed a direct relationship, indicating an increase in troponin I concentration with rising serum IGF-I levels. This indicates that the activity of the angiogenesis marker IGF-I may be associated with the severity and depth of myocardial damage.