bluuebunny/crossref_metadata_2025 huggingface dataset:
Az akut promyelocytás leukémia (APL) legújabb kezelési irányelvei az Európai LeukemiaNet legutóbbi ajánlásaival kiegészítve
Authors: Alizadeh Hussain , Illés Árpád
Published: April 2021

Összefoglaló. Az akut promyelocytás leukémia (APL) ritka, de jól
gyógyítható leukémiatípus. Az APL-es betegek gondozását centralizáltan, az APL
kezelésében jártas kórházakban kell végezni, ahol elérhető hematológiai intenzív
ellátás. Az APL terápiája az elmúlt két évtizedben rohamosan fejlődött az igen
aktív hatású gyógyszerek, a tretinoin és az arzén-trioxid bevezetésével. Immáron
a hagyományos citotoxikus kemoterápia alkalmazása nélkül kezelhető a betegség. A
legújabb klinikai irányelvek többféle kezelési stratégiát tartalmaznak, ezek egy
része továbbra is alkalmazza a citotoxikus kemoterápiát. Ily módon számos
kezelési lehetőség áll a gyakorló hematológus rendelkezésére, amikor egy új
APL-es beteg ellátását tervezi. Az elmúlt három évtized multicentrikus
vizsgálatai igazolták az ATRA + kemoterápia, majd később a kemoterápiával vagy
anélkül adott ATRA + ATO alkalmazásának hatásosságát. Az APL optimális
kezeléséhez azonban a diagnózis korai felállítása, az agresszív szupportív
beavatkozások bevezetése, a kezeléssel összefüggő szövődmények megfelelő
rendezése és a mérhető reziduális betegség (az MRD) monitorozása is
hozzátartozik. A szerzők az akut promyelocytás leukémia legújabb kezelési
irányelveit foglalják össze.

Summary. Acute promyelocytic leukemia (APL) is an uncommon but
highly curable leukemia. Treatment of APL patients should be centralised in
hospitals with proven experience in APL treatment and haematological intensive
care. The treatment of acute promyelocytic leukemia (APL) has evolved rapidly in
the past two decades after the introduction of highly active drugs, including
tretinoin (all-trans-retinoic acid) and arsenic trioxide. It is now possible to
treat this disease without the use of traditional cytotoxic chemotherapy.
Today’s clinical guidelines include multiple regimens, some of which continue to
use cytotoxic chemotherapy. This leaves the practicing oncologist with multiple
treatment options when faced with a new case of APL. Multicenter studies over
the past three decades have demonstrated the efficacy of ATRA plus chemotherapy
and, subsequently, of ATRA plus ATO, with or without chemotherapy. However, the
optimal management of APL also requires early diagnosis, institution of
aggressive supportive measures, appropriate management of treatment-related
complications and monitoring of measurable residual disease (MRD). The authors
summarizes the updated guidelines in the management of acute promyelocytic
leukemia.
EFFICIENCY IMPROVEMENT OF THE CYCLIC STEAM TREATMENT OF WELLS IN THE UPPER PERMIAN DEPOSIT OF THE USINSKOYE FIELD BASED ON THE HYDRODYNAMIC MODEL
Authors:   PermNIPIneft branch of LUKOIL-Engineering LLC in Perm, Savchik Maksim B. , Ganeeva Daria V. ,   PermNIPIneft branch of LUKOIL-Engineering LLC in Perm, Raspopov Aleksei V. ,   PermNIPIneft branch of LUKOIL-Engineering LLC in Perm
Published: April 2021

Development of the Upper Permian high viscosity oil deposit is expected to involve thermal methods of enhanced oil recovery, in particular, cyclic steam treatment of wells. The simulator used for the deposit modeling is to be capable of computing the change in the rock fluid thermal properties, and of solving the heat and mass transfer equations. The modeling of the cyclic steam treatments used CMG STARS, a numerical simulator with a wide range of applications including modeling of thermal processes. The cyclic steam treatment includes three basic stages, such as the steam injection period, the soak period, and the production period. The number of cycles has been selected by computation on the basis of an optimum well operation. To determine the optimum quantity, computations with 7, 5 and 3 cycles were performed. Another predictive computation was performed for a well operation without cyclic steam treatments. The computations helped to determine the operation scenario with the highest cumulative oil production. During the assessment of the cyclic steam treatment efficiency by using hydrodynamic modeling, we obtained dependencies on a number of geological and physical factors, such as steam dryness fraction, formation thickness, steam injection rate, soaking time. The numerical experiments resulted in conclusions and recommendations concerning the case-by-case approach to selecting optimum parameters of the cyclic steam treatments for each individual well, taking into account the structure and specific features. Factor analysis was used to select the optimum parameters for the cyclic steam treatment of the wells drilled in the Upper Permian deposit of the Usinskoye field. For comparison, three predictive scenarios of the well operation have been computed. Cost-performance indicators of the well operation scenarios in the Upper Permian deposit of the Usinskoye field were evaluated, assuming that the wells will be operated in conditions of the natural recovery drive and multiple cyclic steam treatments, in the baseline and recommended scenarios.
Using SAS/STAT to Understand the NCI Joinpoint Regression Software: Testing for a Zero Slope Using Rates of Drugs Overdose Deaths Involving Fentanyl, 2011–2016
Authors: Irimata, Katherine , Malec Donald , Bastian Bringham , Spencer Merianne Rose
Published: April 2021

NHSR 156
Assessment of effective coral rehabilitated in Marine Protected Areas of south Vietnam
Authors: Ben Hoang Xuan , Tuan Vo Si , Hoang Phan Kim
Published: April 2021

More than 20,300 fragment corals belonging to 24 species, eight genera and six families were rehabilitated in marine protected areas of south Vietnam. Mean survival rates of coral fragments ranged from 60–97.7%, the average growth rate of the branched corals was 4.8 mm/month meanwhile the foliose coral was 1.9 mm/month. The survival and growth rate of corals are different among areas because each coral species has different biological characteristics, structure colonies and due to differences in natural conditions each area. The results showed that the growth rate of corals will return to normal after 4 months rehabilitation. The factors affected the effective coral rehabilitation including: Coral reef predators, spatial competition among species, environmental conditions change due to human’s activities; and other factors such as hydrodynamic regimes, cutting fragment corals cause its injury damage. The rehabilitation and protection activities of coral reefs in marine protected areas should be continued and expanded, contributing to the protection of biodivesity, marine resource and sustainable coral reefs ecosystem development.
Optimizing conditions for treatment and extraction of collagen from fan-bellied leatherjacket skin Monacanthus chinensis (Osbeck, 1765)
Authors: Thiet Doan Thi , Ky Pham Xuan , Vy Phan Bao , Anh Nguyen Phuong , Hy Le Ho Khanh , Ha Dao Viet , Boi Vu Ngoc
Published: April 2021

The fan-bellied leatherjacket skin was treated to extract collagen by chemical method. The non-collagenous substances and the pigment in the skin were removed with NaOH and H2O2, respectively. Collagen was extracted with acetic acid. The treatment and extraction conditions were optimized by response surface methodology. The concentrations, skin/solution ratios (g/ml) and times were surveyed. The optimum conditions to remove the non-collagenous substances were as follows: the concentration of NaOH at 0.15M, the ratio (g/ml) at 1/13.9, time at 56.9 hours. Using H2O2 with the concentration at6%, the skin/solution ratio (g/ml) at 1/2, time at 10 minutes were suitable values for skin pigmentation removal. For collagen extraction, the concentration of acetic acid at 0.53M, skin/solution ratio at 1/9.6 g/ml and time in 59.6 hours were optimal.
Certain properties of nanohydroxyapatite obtained from Lates calcarifer fish bone
Authors: Hy Le Ho Khanh , Ha Dao Viet , Ky Pham Xuan , Anh Nguyen Phuong , Vy Phan Bao , Thiet Doan Thi
Published: April 2021

Fish bone by-products are considered as abundant source of hydroxyapatite (HAp). The preparation of HAp from fish bones not only contributes to improving the value of by-products but also minimizes negative impacts on the environment. In this study, nanohydroxyapatite was successfully obtained from Lates calcarifer fish bone purchased from seafood export company in Khanh Hoa province. Fish bones were under alkali treatment and then heated at 600oC within different time intervals of 1, 2 and 4 hours. Analysis of XRD and SEM showed that the calcium formed was completely single-phase and possessed an average size of 50–64 nm depending on the calcination time. The results of the Ca/P molar ratio from 1.839 to 1.847 prove that the nano-HAp powders are B-type biological hydroxyapatites, which has been confirmed by FTIR spectrum. In addition, the content of heavy metals such as As, Pb, Hg, Cd is detected within safety limits. These properties allow nano-HAp powders to be applied in food and medicine fields.
Structural analysis of novel amino acid substitutions in SARS-CoV-2 spike protein receptor-binding domain
Authors: BİTERGE SÜT Burcu
Published: April 2021

There are several novel amino acid substitutions in SARS-CoV-2 spike protein, which could account for the increased infectivity of this newly emerged virus. Therefore, in this paper we aimed to evaluate the potential effects of these amino acid substitutions on protein structure and function. For this purpose, we made use of several state-of-the-art computational tools and performed in silico analyses on protein similarity, 2D and 3D structure, ligand binding and biological function. We found that some of the novel amino acid changes caused significant structural alterations both at the secondary and tertiary structure level, possibly affecting the interaction between the spike protein receptor-binding domain (RBD) and ACE2, as well as other ligands. In conclusion, data we provided here is a significant contribution to our current knowledge of the SARS-CoV-2 virus and will aid in having a better understanding of its molecular differences, mechanism of infection and the cellular processes it affects in the host in order to develop better therapies and vaccines.
Die Rolle von Wissenschaft und Innovation in der Flughafenumfeldregion : Herausforderungen und Perspektiven
Authors: Mietzner Dana , Hartmann Frank , Melzer Klaus-Martin , Vossel Markus , Bautz Franziska , Wiechers Henning
Published: April 2021

Mit der Eröffnung des Flughafens BER im Oktober 2020, dem Bau der Gigafactory von Tesla in Grünheide und der Microvast-Batteriefabrik in Ludwigsfelde beginnend im Sommer 2020 sind deutlich Signale für den Beginn einer neuen Phase der Entwicklung der Flughafenumfeldregion erkennbar. Konzeptionell begleitet wird dieser Prozess zunächst durch die Fortschreibung des Gemeinsamen Strukturkonzeptes der Flughafenregion. Sie wurde von der Kommunalen Arbeitsgemeinschaft Dialogforum Airport Berlin Brandenburg (KAG DF) im Jahr 2019 beauftragt und soll voraussichtlich im April 2021 abgeschlossen und bestätigt werden (vgl. Dialogforum-BER, 2020). Hinzu kommen die Grundlagenermittlung Verkehr Flughafenregion BER, die mit dem Bericht vom August 2019 abgeschlossen wurde, sowie der Dachmarkenprozess „Entwicklungsstrategie und Dachmarkenkonzeption für die Technologie- und Wissenschaftsregion Zeuthen – Wildau – Königs Wusterhausen“, der im Jahr 2019 begann und dessen Ergebnisse im Sommer 2020 veröffentlicht wurden. Schließlich beauftragte das Ministerium für Wissenschaft, Forschung und Kultur des Landes Brandenburg die Technische Hochschule Wildau Ende 2019 mit der Analyse der Flughafenumfeldregion BER, für die die Frage nach der Beschaffenheit und Ansätzen einer Stärkung des Wissenschafts- und Technologiepotenzials der Region leitend war. Mit der Analyse sollten die Perspektiven verschiedener Akteur/innen, insbesondere aus den Bereichen Wirtschaftspolitik und Wirtschaftsförderung sowie Wissenschaft, auf die Region erhoben, aktuelle Projekte gesichtet und der Stand von Entwicklungsvorhaben, die mit der Entwicklung der Region in Zusammenhang stehen, ermittelt werden.
A magyar haderő útja Padovától Trianonig 1918–1920
Authors: Andaházi Szeghy Viktor
Published: April 2021

A tanulmány a magyar haderő újjászervezésére fókuszál az olasz fegyverszünettől a trianoni béke ratifikálásáig terjedő periódusban. Az írás a kortárs katonai és politikai vezetők előtt álló problémákat veszi sorra, amelyeket a Szövetséges Hatalmak egymásnak is ellentmondó elvárásai és a források hiánya határoznak meg. A magyar katonai vezetők legfontosabb célja ebben az idõszakban a hadsereg és a harckészültség lehetőség szerinti megőrzése volt – mialatt 13 kormány volt hivatalban, némelyek egy időben, az ország különböző területein. Ezt a kaotikus fejezetet a nemzetközi kapcsolatok terén a trianoni békeszerződés zárta, amely egyúttal a békeszerződés felülvizsgálatának bölcsőe is volt.
Az indokínai háború kutatásának sajátosságai
Authors: Harangi-Tóth Zoltán
Published: April 2021

Az indokínai háború formálta a mai, modern Franciaország képét, és nyomot hagyott az ország fegyveres erején is – amely napjainkban az Európai Unió meghatározó hadereje – az pedig ismert tény, hogy a szövetséges országok hadtörténetének megismerése hozzájárulhat a hatékonyabb együttműködéshez. Ezen a nyilvánvaló tényen túl azonban az indokínai háború hadművészet fejlődésére gyakorolt hatása az, ami a kutatásokat indokolttá teszi, mégis hazánkban a konfliktus hadtörténeti feldolgozása és kontextusának vizsgálata meglehetősen hiányos. Jelen publikáció a téma sajátosságait és a kutatói, valamint oktatói előtt álló nehézségek veszi számba.
Breakwaters of the "1 st Island-chain" : Structural similarities in Japan and Taiwan’s limited deterrence strategies
Authors: Bartók András
Published: April 2021

A changing balance of power between Washington and Beijing has dominated discourse on regional and global trends in both academic and policy circles. While ample body of literature deals with the question of deterrence vis-a-vis the US and China, less attention is given to medium powers in the Asia Pacific regarding their policy decisions to adapt to a dynamic balance of power. This paper looks at how two key regional players, Taiwan and Japan, have shifted their strategic perceptions from territorial defense to a more active deterrence regarding the PRC. It gives an overview of the state of the theory of deterrence in IR and Security Studies literature, followed by an assessment of changing Chinese military capabilities. It then shows the strategic perceptions and expressed intentions of Japanese and Taiwanese defense reforms that highlight deterrence as a core concept. The two regional actors’ deterrence strategies share core similarities and represent special cases of deterrence thinking that can contribute to theoretical analysis of deterrence strategy in the 21st century
Megerősített együttműködés, változó geometria, PESCO
Authors: Molnár Anna , Szabolcs Laura
Published: April 2021

Az Európai Unió közös biztonság- és védelempolitikája a 2016-os globális stratégia elfogadása óta védelmi együttműködés terén is mélyül – ennek egyik meghatározó pillére a 2017-ben érvénybelépett állandó strukturált együttműködés, a PESCO. A kooperációs forma lehetőséget ad a differenciált vagy rugalmas integrációra – ezért fontosnak tartjuk megvizsgálni, hogy a jelenleg futó projektekben miként alakul az egyes tagállamok együttműködési hajlandósága, és ezzel összefüggésben a megerősített együttműködés vagy változó geometria megvalósulása. A tagállamok csoportosítását különböző szempontok szerint meghatározott védelmi (vagy védelempolitikát is érintő) formációk, szövetségek, egyezmények tagjaitól való eltérések és hasonlóságok alapján végeztük el, illetve elkülönítettük az Unió Tanácsa által meghatározott projektcsoportokat. Az egyes projektkategóriákban részt vevő államok együttműködési preferenciáit gráfokkal ábrázoltuk.
Las afinidades meridionales de la flora de los bosques montanos de México
Authors: Rzedowski Jerzy
Published: April 2021

Antecedentes: En la flora de los bosques de coníferas, encinos y mesófilos de montaña de México destacan los elementos fitogeográficos septentrional y meridional; este último se analiza en la presente contribución.

Pregunta: ¿En cuál de los tipos de vegetación enumerados es más manifiesta la afinidad florística meridional?

Grupo estudiado: Fanerógamas (Spermatophyta).

Área de estudio: Principalmente México y Sudamérica.

Métodos: Se realizó la revisión de literatura para integrar una lista de géneros de la flora de nuestro país de distribución esencialmente restringida al continente americano y que están más diversificados en Sudamérica que en México. Se depuró con la consulta de revisiones taxonómicas y de estudios de la filogenia; se aceptaron solamente los de probable origen en el hemisferio sur y pertenecientes a familias de la misma procedencia.

Resultados: Se completó un catálogo de 84 géneros para 39 familias. Para cada uno se proporciona el número de especies conocidas en total y las presentes en México. Se señala su distribución geográfica, mediante la definición de sus extremos boreal y austral.

Conclusiones: Con base en la lista fue posible definir que a) la afinidad meridional es más pronunciada en la flora del bosque mesófilo de montaña que en los de coníferas y encino.  b) la mayor parte de los elementos australes encuentra el límite de su distribución en el centro de México, algunos en Chiapas y pocos hasta Canadá. c) Aunque es probable que el arribo de algunos es relativamente reciente, otros estuvieron presentes en México al menos desde el Mioceno temprano.
Measurement of probabilistic ballast particle dynamics using Kli-Pi
Authors: Broekman A , Grabe P J
Published: April 2021

At first glance the operational performance of ballast appears trivial in its simplicity. However, various mechanisms affect the performance of the ballast both on a macroscopic scale and discrete (mesoscale) particle level. The importance of experimental studies to establish the influence of the granular fabric has been highlighted repeatedly by other researchers. This paper describes a method by which quantitative metrics and statistics can describe the probabilistic response of railway ballast. The measurements were obtained with the installation of a set of customised wireless inertial measurement unit (IMU), referred to as Kli-Pi, in the granular layers of a heavy-haul railway line located in South Africa. The results indicate a complex interaction of displacement and rotation, in all three spatial dimensions. The high-frequency measurements provided approximations of the particle's kinetic and potential energy (mechanical work) in addition to the indirect quantification of changes to the granular fabric. Finally, the descriptive statistics of the mechanical work provided an indirect measure of the confinement and coordination number of the particle, together with supporting evidence of the underlying probabilistic, instead of the expected deterministic response. These results strongly agree with the findings of existing literature that has, to date, been confined to theoretical study.
Reliability performance of bridges designed according to TMH7 NA load model
Authors: Lenner R , Basson S E , Sýkora M , Van der Spuy P F
Published: April 2021

The current code of practice for the design of highway bridges in South Africa is called Technical Methods for Highways 7 (TMH7). It was first published in 1981 and is largely based on the loading provisions of the BS5400. The purpose of this study is to carry out an investigation into the reliability performance of new highway bridges designed according to TMH7. Past studies have identified deficiencies in the traffic load model. A case study considering isolated traffic load effects and sagging moment on a simply supported bridge indicates that NA loading generally performs well for spans ranging from 15 to 50 metres. However, a poor reliability performance is seen for short-span narrow bridges, especially for 5 m and 10 m spans where the number of traffic lanes is equal to the number of notional lanes for NA loading. To study the reliability performance of a critical element, flexural behaviour of a 20 m twin-spine simply supported deck is then investigated. The results agree with the first case study. It is, however, recommended to verify the presented findings by investigation based on data from other heavy-freight routes and to account for continuous structures and shear load effects.
The variability in commercial laboratory aggregate testing for road construction in South Africa
Authors: Breytenbach I J , Fourie H G
Published: April 2021

Simple data comparisons were undertaken using project data to illustrate the need for duplicate test analyses in road construction material investigations for hard rock aggregate sources. Test data was sourced from projects commissioned by the South African National Roads Agency SOC Limited (SANRAL). All test results except the polished stone value were reported by commercial geotechnical laboratories that are accredited with the South African National Accreditation System (SANAS). Only samples subjected to duplicate test analyses were used, as this method allows direct comparisons. The tests used for comparison included the polished stone value, wet and dry versions of the Aggregate Crushing Value test, wet and dry versions of the 10% Fines Aggregate Crushing Value test, the ethylene glycol-soaked version of the 10% Fines Aggregate Crushing Value test, and the water absorption test of both the fine (-5.00 mm) and coarse (+5.00 mm) material fractions. The results show that duplicate testing is firmly justified, as test results reported were often highly variable, despite all participating laboratories being SANAS-accredited and using standardised methods. Further consideration was then given to the additional cost of duplicate testing at project stage investigations compared to the cost implications of having erroneously reported materials failing in service or having good-quality materials rejected.
Design and construction of laboratory-scale activated carbon, gravel and rice husk filter columns for the treatment of stormwater runoff from automobile workshops
Authors: Ataguba C O , Brink I
Published: April 2021

The design and construction of low-cost laboratory-scale filter columns using locally available Nigerian filter materials - granular activated carbon (GAC), gravel (GR) and rice husk (RH) - were carried out and reported. The filter materials and columns were designed, constructed and used for the treatment of stormwater runoff from selected automobile workshops in Nigeria over a period of three rainy months. The combined granular activated carbon and rice husk filter systems performed best with pollutant removal efficiency of 58%. It was shown that the materials, considered as waste, could be recycled and used as filter materials in the treatment of stormwater from automobile workshops. This low-cost technology for stormwater runoff treatment, especially for automobile workshops at large scale and in-situ, can be further explored.
MIBI staining v1
Authors: MB Bosse Marc , Bendall Sean , Angelo Mike
Published: April 2021

This protocol is a the standard FFPE tissue staining procedure recommended for Multiplex Ion Beam Imaging Time of Flight instrument (MIBI_TOF) developed in the Sean C. Bendall and Michael R. Angelo labs. The protocol has been successfully used for MIBI and is the result of extensive optimization experiments. It is inspired from state-of-the art of immunohistochemistry staining procedures but differs in some very important steps, namely, glutaraldehyde fixation and final washes prior tissue dehydration. Failure to follow exactly all steps described in this procedure may result in inconsistencies in output data after MIBI_TOF acquisition.
Методы визуализации околощитовидных желез и паратиреоидная хирургия: руководство для врачей
Authors: Калинин А.П. , Павлов А.В. , Александров Ю.К. , Котова И.В. , Патрунов Ю.Н. , Пампутис С.Н. , Оралов Д.В.
Published: April 2021

В руководстве рассматриваются различные аспекты визуализации околощитовидных желез в связи с паратиреоидной хирургией, и прежде всего с проблемой первичного и вторичного (почечного) гиперпаратиреоза. Представлены основные существующие в настоящее время методы до и интраоперационной визуализации околощитовидных желез, анализируются причины возможных ошибок при интерпретации результатов проведенного исследования. Особое внимание уделено клиническим признакам гиперпаратиреоза. Эта книга – первое в России пособие, посвященное визуализации околощитовидных желез в связи с паратиреоидной хирургией. Предназначено для хирургов эндокринологов, специалистов ультразвуковой, лучевой и изотопной диагностики, биохимиков, а также для врачей смежных специальностей (терапевтов, терапевтов эндокринологов, гастроэнтерологов, травматологов, урологов, челюстно лицевых хирургов).
Linking Facebook to WordPress for educational purposes – a proposed architecture sustaining social learning
Authors: Bogoslov I. A. , Georgescu M. R. , Pitic A. G.
Published: April 2021

Ensuring social educational processes does not only represent a trend in terms of the evolution of e-Learning systems, but also one of the main points of interest targeted by the developers of certain social platforms. In fact, raising awareness with respect to the importance of using Social Media tools in education leads to a two-way approach: both by integrating social tools into e-Learning systems and by integrating learning facilities into Social Media platforms. Over time, the social network Facebook has benefited from intense use at global level, including in e-Learning processes. In order to meet the current needs in terms of teaching and learning, Facebook has provided users with built-in opportunities to facilitate social learning processes. However, expanding the Social Learning features integrated in Facebook can be a challenge at present, because of the policies imposed for the social network. The present article outlines a proposed architecture for extending the Social Learning functionalities offered within Facebook Groups by ensuring the correlation with WordPress open-source CMS. Aspects related to how the correlation between the two platforms can be ensured, the necessary tools and the steps involved will be discussed. Also, the main implications and advantages offered by such an architecture and the identified limitations will be highlighted.
A STUDY OF FATAWAS (RELIGIOUS DECREES) REGARDING TEACHING AND LEARNING ENGLISH LANGUAGE
Authors: Et. al. Muhammad Imran Saeed,
Published: April 2021

The present study discusses Muslim religious scholars' attitudes in the sub-continent when it was under British rulers' influence.The study focuses on the causes of religious scholars' indifference and their hostile attitudes towards the English language in the pre-partition era. The data has been collected from various fatawa books written by Muslim religious scholars during the pre-partition period. Researchersanalyse the fatawas (religious decrees) under the paradigm of Islam and English language and attitudes of religious scholars in the pre-partition era.The fatawashas been examined through a content analysis of the text. The study's findings reveal that Muslim religious scholars wereagainst English language learning and teaching to such an extent that they issued Fatawas declaring that learning and teaching English was illegitimate (Najaiz) because they believed that Christian missionaries were against Muslims and Islam. Thefindingsfurther suggest that future English language curriculum planning should considersociety's cultural and religious requirements so that everyone in the community can learn English according to their needs. The study also highlightsculturalharmonyfrom the perspectiveofEnglish languagelearning.
El autoestudio y la participación social para mejorar la calidad de la Educación
Authors: Rentería Castro Enrique
Published: April 2021

El siguiente artículo hace una breve descripción de la propuesta que lleva a cabo la Federación Mundial de Clubes, Centros y Asociaciones UNESCO para dar seguimiento a los compromisos que define la UNESCO con respecto a la Calidad Educativa en la región de Amé[1]rica Latina y El Caribe. Dicha propuesta consiste en promover en las instituciones educativas la implementación de la autoevaluación de su gestión pedagógica y sus respectivos procesos académicos, con el propósito de tener resultados y evidencias sistematizadas que permitan realizar estudios comparados en la región para establecer planes de mejora. Y permitir que los docentes y las autoridades educativas estén en posibilidad de elegir las prácticas de calidad más adecuada en su escuela y cumplir sus objetivos institucionales. La propuesta se realiza a través del Modelo de Dirección por Calidad Integral, el cual permite medir avance de los indicadores y la evaluación de procesos para determinar la mejora continua, lo cual no es posible realizar sin la implementación del autoestudio.
Igualdad y adulto mayor. Entre utopías y realidades
Authors: Verdecia Rodríguez Asseneth
Published: April 2021

El envejecimiento poblacional es un fenómeno nuevo de la sociedad de finales del siglo XX con tendencia notable al incremento, que planteará diferentes desafíos en todos los ámbitos de la vida humana. La población adulta mayor requiere entonces de una protección especial, con respaldo en normas jurídicas atemperadas al contexto socioeconómico contemporáneo y en políticas sociales públicas adecuadas y armónicas. Ello hace indispensable no solo el reconocimiento de sus derechos inherentes a su condición de ser humano con características fisiológicas diferentes y en estado de vulnerabilidad, sino una mirada desde la Igualdad como derecho y principio básico y fundamental, sobre todo, porque su práctica permite el disfrute de otros derechos. La correcta y consciente interpretación de la Igualdad contribuirá a garantizar la atención, tratamiento y protección integral que demandan los adultos mayores, para que el ejercicio pleno de sus derechos pase de utopía, a realidad concreta y posible.
Aproximación a la ética informática en la Educación Superior
Authors: Aguilera Borjas Madelín , Aguilera Almaguer Osmany , Pérez Alí Osmán Edilberto de Jesús
Published: April 2021

Los cambios acelerados que producen en la sociedad las Tecnologías de la Información y las Comunicaciones (TIC), están causando una intensa revolución cultural para la humanidad, a la vez que contraen grandes retos y ofrecen un enorme potencial para contribuir al desarrollo de la Educación Superior. En tal sentido, posibilitan realizar transformaciones para ofrecer una educación actualizada y de calidad, a fin de generar ambientes de aprendizaje enriquecidos. Para toda institución universitaria constituye un reto alcanzar una Ética Informática acorde con la moral y los principios derivados de nuestro estado, a tal efecto, pretendemos con el presente material presentar una aproximación a la Ética Informática en la Educación Superior, sobre todo en la Universidad de Holguín. Para ello, se parte de criterios derivados de trabajos científicos realizados por algunos autores nacionales e internacionales para llegar a conclusiones precisas sobre el tema. Su nivel de aplicación se precisa a partir de la imposición de la ética no como una moda, sino como una necesidad, una indispensable herramienta para enfrentar los nuevos desafíos que surgen frente al desarrollo científico-tecnológico. Dentro de este contexto, se releja un impacto positivo en el comportamiento ético y responsable de los usuarios informáticos durante la utilización de las TIC en la Universidad de Holguín, lo que constituye un factor fundamental para alcanzar el éxito de nuestra institución.
La psicología diferencial aplicada a alumnos con bajo aprovechamiento académico
Authors: De la Torre Batista Yanet , Parra Michel Pastor , Chimbinda Samandjata Bernice Nanjala
Published: April 2021

La investigación que se presenta, da respuesta a una problemática que interfiere en el desarrollo del aprendizaje en la escuela. Tiene como objetivo general: analizar las particularidades de los alumnos con bajo aprovechamiento académico en la Escuela Primaria “Cató” en la ciudad de Sumbe. Para dar respuesta al mismo se presentan las premisas teóricas acerca del tema en cuestión a partir de una metodología cualitativa- cuantitativa con la utilización de métodos teóricos, empíricos y estadísticos que permitieron arribar a los siguientes resultados: el tratamiento a las diferencias individuales en los alumnos con bajo aprovechamiento académico en dicha escuela es insuficiente para un buen aprendizaje de los mismos; esto permitió llegar a conclusiones y proponer recomendaciones.
Crowsourcing through Twitter for inovation
Authors: Cripps Helen , Kumar Singh Abhay , Mejtoft Thomas , Salo Jari
Published: April 2021

This research investigates the role and use of Twitter in business markets and benefits of using open social media channels to crowd source information to support innovation and build relationship in the context of business-to-business (B2B) marketing. This study is based on a combination of methodologies, 52 face-to-face interviews across five countries are compared with a sample of their Tweets using Structural Topic Modelling (STM) which enabled triangulation between stated use of Twitter and respondent’s actual Tweets. The research confirmed that individuals used Twitter as a source of information, ideas and innovation within their industry. Twitter enables the building of relevant business relationships through the exchange of new, expert and high quality information within like-minded communities in real time, between companies and their suppliers, customers and also their peers. This research highlights the business relationship building capacity of Twitter as it enables customer and peer conversations that eventually support the development of product and service innovations.
What makes IS implementation succesful? A study on implementation effectiveness
Authors: Ende Saskia van den , Ravesteijn Pascal , De Waal Benny M.E.
Published: April 2021

It has been noted that implementation climate is positively associated with implementation effectiveness. However, the recipe for a successful implementation of IS/IT systems still doesn’t exist. Specifically, it is unclear what a "good" implementation climate requires, what it should be, and to what extent the acceptance and success of the implementation of a new IS/IT system is affected. Despite success and opportunities for organizations that innovate with information systems (IS) and information technology (IT) in general there are also many failures of IS/IT implementations caused by both technical and non-technical problems. This study, based on the Klein-Sorra model of implementation effectiveness, shows that skills and innovation-values fit do significantly influence intention to use in the context of our questionnaire-based survey, the implementation of a new document management system (DMS) at the Dutch Police. Survey data was collected from 41 end-users. For practitioners, this research offers practices to be considered during implementation of a new system.
Iowa Writer's Workshop
Authors:   The Program Era Project (PEP)
Published: April 2021

The Program Era Project (PEP) has assembled three related datasets of information on the Iowa Writers’ Workshop (IWW). The first two datasets include the thesis and matriculation records of the IWW from the first creative thesis submitted in 1941 until Spring 2014. These data were initially derived from University of Iowa Library catalog records of MFA theses. Additional data (primarily genre and advisor) were filled in by checking bound copies of theses held in the University Archives. Also included are small number (~1.5% of total) of BA records from other institutions for early faculty and additional degrees earned at Iowa by IWW grads and faculty (e.g., several IWW graduates also have Nonfiction Writing Program MFAs).
Effect of Different Preservation Time of Chilled Semen on the Fertility of Field Indigenous Ewes
Authors: Saha A. , Asaduzzaman M. , Akter S. , Bari F.Y.
Published: April 2021

Background: Artificial insemination (AI), among all the fundamental systems of animal breeding, has proved to be the best and efficient method for the rapid improvement of livestock for maximum use of superior genetic merit of males on numerous dams. The frozen AI in sheep is, to date, not fulfilling the farmer’s need. Therefore, the present study aimed to determine the pregnancy rate in indigenous ewes with chilled semen preserved at different hours. Methods: Semen was collected from three indigenous rams using an artificial vagina and evaluated for its quality both in the fresh and chilled stage at 12 h, 24 h and 48 h before insemination. Trans-cervical insemination was performed in PGF2α synchronized ewes. Pregnancy was confirmed by ultrasonography at 50-60 days of gestation. Result: The motility, viability and normal sperm values of chilled semen decreased significantly (p less than 0.01) with increasing the duration of preservation. However, the quality of chilled semen was acceptable level for insemination. The pregnancy rate was significantly varied (p less than 0.01) and the higher pregnancy rate (64.28%) was achieved when AI was performed using semen stored at 4oC for 12 h than 24 h (58.33%) and 48 h (50%), respectively. Therefore, increased the duration of preservation time of different chilling process negatively affect the semen quality and the pregnancy rates.
Redescription and New Host Record of Heteraxinoides atlanticus (Monogenea: Heteraxinidae) from the Gills of Nemipterus japonicus (Bloch) and Its Systematics
Authors: Verma A.K. , Verma J.
Published: April 2021

Background: Heteraxinoides atlanticus Gayevskaya et Kovaleva (1979) is described from the locality of Arabian Sea, India. This monogenean species is first time reported from India, infesting the gills of Nemipterus japonicus (Bloch). The present study redescribes H. atlanticus and its phylogenetic status using morphometric and molecular tools. Methods: A total of 35 parasites were collected from the 234 specimens of Nemipterus japonicus at Mumbai, India. The temporary and permanent mounts were prepared for the morphometric analyses of H. atlanticus. For PCR, the genomic DNA was isolated from the parasites using primers for 18S rDNA, 28S rDNA and mtCOI gene. The obtained DNA sequences were subjected to different bioinformatics softwares (BLASTn, Clustal Omega and MEGA) for phlyogenetic analyses. Result: Phylogenetic analyses with the help of partial 18S and 28S rDNA sequences of H. atlanticus and other available sequences of heteraxinids provided the better understanding of relationship in the family Heteraxinidae. Another species, H. karachiensis Hadi and Bilqees (2014) showed similar morphological features such as number of clamps and structure of genital atrium to H. atlanticus except few minor differences, so it must be considered as synonym of H. atlanticus and placed into Heteraxinidae instead of Axinidae.
Investigation of Mutations in Exon 12 Of β-MYH7, 16 Of MYBPC3 and 2 Of TCAP Gene in Dogs with Dilated Cardiomyopathy using PCR-SSCP Technique
Authors: Vishnurahav R.B. , Ajithkumar S. , Pillai Usha Narayana , Unny N. Madhvan , Martin K.D. John , Aravindakshan T.V.
Published: April 2021

Background: Dilated cardiomyopathy is the important myocardial disease and one of the most common cause of death in the medium to large size dog breeds worldwide. The disease is characterized by dilatation of cardiac chambers and thinning of walls leads to systolic failure. Mutations in some sarcomere genes leads to cardiomyopathy in humans. Sarcomere is an important multifunctional protein network involved in the signal reception and transduction. Mutations in β-MYH7, MYBPC3 and TCAP genes produce alterations in the morphology of heart (hypertrophy or dilatation). Methods: In this study twenty apparently healthy and twenty five dogs with dilated cardiomyopathy (DCM) were selected from patients reported or referred to University Veterinary Hospital and Teaching Veterinary Clinical Complex, Mannuthy (2015-2017) based on the clinical examination, radiographic, electrocardiographic, haematobiochemical and echocardiographic studies cardiac disorders (Dilated cardiomyopathy and hypertrophic cardiomyopathy) were confirmed. Result: In the present study we investigated genetic alterations of exon 12 of β-MYH7, 16 of MYBPC3 and 2 of TCAP gene in dogs by polymerase chain reaction -single stranded confirmation of polymorphism (PCR-SSCP). Polymerase chain reactions were analysed using acrylamide gel and samples with different pattern of bands were sequenced. Polymerase chain reaction-SSCP showed different migration of band pattern in the intron 1 of TCAP gene in one sample.
Physiological Traits Study to Identify Suitable Mustard Genotype for Late Sown Condition of Northern Part of India
Authors: Yadav Akanksha Singh , . Lallu , Singh Maharaj
Published: April 2021

Background: Indian mustard (Brassica juncea L.) is a prominent seed crop grown in most of the northern part of India. It is also grown in different cropping systems where sowing time differs as per availability of vacant field prior to preceding crop. Being a rabi season (winter) crop its physiological as well as morphological developments are markedly influenced by temperature condition. Methods: An investigation was carried out during rabi season of 2010-11 and 2011-2012 at oilseeds research farm Kanpur (UP) with 4 sowing dates (30th Sept. 11th 21st, 31st Oct.) and 5 genotypes (Kranti, Maya, PAC-437, PBR-357, Rohini) of mustard on sandy loam soil under irrigated condition to study different physiological and yield attributing characters. Result: The results shown that among the sowing dates, 11th October registered the highest values of specific leaf weight (SLW), Crop Growth rate (CGR) estimated at 60-90 DAS, seed yield and oil content. The early sowing at 30th Sept. registered significantly lowest seed yield (1880 Kgha-1) and seed oil content (38%). In case of genotypes, PAC-437 registered highest values of SLW (29.60 mgcm-2), NAR (113.3 mg dm-2 day-1), RGR (26.7 mg g-1 day-1), CGR (0.94g plant-1 day) at 60-90 DAS, seed yield (2079 kg ha-1). The interaction effect of sowing date × genotypes was found significant in most of the cases. Thus, the results concluded in Indian condition specially the northern part, 11th October proved to be the optimum sowing time of mustard. As far as the genotype is concerned, Kranti perform well of this date of sowing while PAC-437 proved its superiority over other genotypes as well as different sowings date of October month.
Establishment Techniques on Yield and Economics of Pigeon Pea [Cajanus cajan (L.)] in North Western Zone of Tamil Nadu
Authors: Sivakumar C. , Krishnaveni A. , Pandiyan M. , Tamilselvan N.
Published: April 2021

Field experiments were conducted to study the effect of establishment techniques on yield and economics of red gram [Cajanus cajan (L.)] under irrigated condition at Regional Research Station, Tamil Nadu Agricultural University, Paiyur - 635 112,Tamil Nadu, India during Kharif season of 2013-14 and 2014-15 respectively in randomized block design with four replications. The treatments are line sowing/dibbling of seeds, sowing behind the country plough, sowing in polybag and transplanting at 25 and 40 DAS, sowing in portrays and transplanting in 25 and 40 DAS. The redgram variety LRG 41 was used for study. The results revealed that, dibbling of seeds in lines recorded higher grain yield of 2351 kg ha-1, net income of Rs.99495/- and B:C ratio of 3.39. Thus, dibbling of seeds in lines recorded 6% higher over sowing in poly bag and transplanting at 25 DAS and 27% higher yield over sowing behind the country plough. Considering yield and economics, line sowing seems to better option for the farmers followed by sowing in polybags and transplanted in 25 DAS. Under transplanted situation, transplanting of seedlings at 30 DAS was more suitable where the monsoon was delayed for 30 to 45 days under rainfed situation.
BÁCSKAI VONATKOZÁSOK MARGALITS EDE KORAI FRAZÉMAGYŰJTEMÉNYÉBEN
Authors: Rajsli Ilona
Published: April 2021

Margalits Ede Bácskai közmondások és szólásmódok című gyűjteménye 1877-ben jelent meg Baján, s ez a kiadvány a szerző későbbi monumentális szóláskiadványainak az úttörője is egyben. Ez a korai kis szólástár jelzi a frazémák gyűjtése felé forduló Margalits szakmai-tudományos attitűdjét. A szerző a bevezetőben közli a számára releváns gyűjtési és szerkesztési elveket, ugyanakkor körvonalazza egy országos szintű gyűjtemény vízióját is. A későbbi adattárak gyakorlatától eltérően e korai kiadványban még szoros betűrendben sorakoznak a szólások, így vezérszavak sincsenek. Tanulmányunkban e bácskai frazémakiadvány bemutatásán keresztül a területi kötődésű szólásokban előforduló lokális jegyek kiemelésére törekszünk: amilyen a nyelvjárási jelenségek, a tájszavak előfordulása, a toponimák felbukkanása a szólásokban, a tájhoz kötődő anekdotikus frazémák jelenléte, az etnosztereotípiák sokszínűsége. Erdélyi János gyakorlatához hasonlóan Margalits is gyakorta fűz magyarázatot a kevésbé ismert frazémákhoz, a helyi vonatkozású szólásanyag esetében pedig a frazémát indukáló (valós vagy vélt) történetet is közli, számos igen értékes – területi kötődésű – adomával gazdagítva a vidék hely- és művelődéstörténetét.
A DIDAXISTÓL AZ ESZKATOLÓGIÁIG
Authors: MEDVE Zoltán A.
Published: April 2021

Jelen írás a Faust-jelenség irodalmi változatainak igyekszik vázlatosan a nyomába eredni. A filológiai-kontaktológiai munka a Faust-legenda variációinak tematikus, motivikus, poétikai hálózatát próbálja meg nagy vonalakban felvázolni. Annak feltérképezésére tesz kísérletet, hogy a Faust-legenda hogyan hagyományozódott át egészen a kortárs – mindenekelőtt az európai, még közelebbről a magyar és horvát – irodalmi feldolgozásokban.
BEVEZETÉS A KEGYETLENSÉG VILÁGÁBA
Authors: BARCSI Tamás
Published: April 2021

A dolgozat filozófiai, etikai, szociológiai szempontból a civilizáció, a felügyeleti rend és a kegyetlenség fogalmai mentén vizsgálja Ottlik Iskola a határon című regényét, illetve Ottliknak a felvetett kérdésekhez kapcsolódó más írásait. A szerző áttekinti, hogy a regényben bemutatott alreáliskolában milyen hatalmi struktúra keretében valósulnak meg a kegyetlenségek, illetve részletesen foglalkozik a mű erkölcsi szemléletének sajátosságaival. A tanulmány amellett érvel, hogy Ottlik egy mikroközösség működésének bemutatásával nyilvánvalóvá teszi a civilizáció „illúzió” voltát, tehát a civilizáció morális rendjének törékenységét, és azt, hogy a civilizációs külsőségek „álcája” mögött egy kegyetlen emberi világ rejtőzhet.
KÉTNYELVŰSÉG, NYELVI TÁJKÉP A SZLOVÁKIAI KOMÁROM VÁROSÁBAN
Authors: SIMON Szabolcs
Published: April 2021

A szlovákiai Komárom (Komárno) lakosságának etnikai összetétele, ezzel összefüggésben nyelvhasználata, nyelvi tájképe folyamatosan változik. A tanulmány alapját jelentő kutatás célja Komárom nyelvi tájképének, kétnyelvűségének feltérképezése volt. A város két autochton nemzetiség lakóhelye, vegyes lakosságú, de magyar többségű település. A bemutatandó kutatás terepmunkával szerzett adatokon alapul. Az adatgyűjtés módszere olyan kérdőíves felmérés, amely során szociolingvisztikai, szociológiai és szociálpszichológiai jellegű változók képezik a vizsgálat tárgyát. A kutatás fontos szempontja az adatközlők nemzetisége/első nyelve, mivel a projekt célja megállapítani az adatközlők véleménybeli orientálódását és attidűdjeit a kétnyelvűséghez, nemzeti önmeghatározásához és az adott település lakosságának asszimilációs tendenciáihoz.