bluuebunny/crossref_metadata_2025 huggingface dataset:
A Contemporary Review on the Critical Role of Nonsteroidal Anti-inflammatory
Agents in Colorectal Cancer Therapy
Authors: Zia Sarabi Parisa , Moradi Mohammad , Bagheri Malihe , Khalili Mohammad Reza , Moradifard Shahrzad , Jamialahmadi Tannaz , Ghasemi Faezeh , Sahebkar Amirhossein
Published: January 2024

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) are widely recognized as effective pain relievers and
function by inhibiting the cyclooxygenase enzyme (COXs). Moreover, they have been found to participate in
various cellular processes through different signaling pathways, such as WNT, MAPK, NF-KB, and
PI3K/AKT/mTOR. This makes them potential candidates for chemoprevention of several malignancies, particularly
colorectal cancer (CRC). However, the use of NSAIDs in cancer prevention and treatment is a complex
issue due to their adverse effects and gastrointestinal toxicity. Therefore, it is crucial to explore combination
therapies that can minimize side effects while maximizing synergistic effects with other agents and to evaluate
the success rate of such approaches in both pre-clinical and clinical studies. In this review, we aim to provide an
overview of the effects of NSAIDs in the prevention and treatment of CRC. We will focus on elucidating the
possible mechanisms of action of these drugs, the signaling pathways involved in CRC, and the potential synergistic
effects when combined with other therapeutic agents.
The Application of Kinesin Inhibitors in Medical Issues
Authors: Nejabat Mojgan , Hadizadeh Farzin , Sahebkar Amirhossein
Published: January 2024

Kinesins are a group of motor proteins in charge of several crucial functions in the cell.
These proteins often bind to microtubules and perform their functions using the energy produced by
ATP hydrolysis. One function of mitotic kinesin, a subclass of kinesin that is expressed during cell
division at the mitotic phase, is to create the mitotic spindle. Uncontrolled cell growth is one trait of
cancerous cells. Traditional anticancer medications still used in clinics include taxanes (paclitaxel)
and vinca alkaloids (vincristine, vinblastine), which interfere with microtubule dynamics. However,
because non-dividing cells like post-mitotic neurons contain microtubules, unwanted side effects
like peripheral neuropathy are frequently found in patients taking these medications. More than ten
members of the mitotic kinesin family play distinct or complementary roles during mitosis. The mitotic
kinesin family's KSP, or Eg5, is regarded as its most dramatic target protein. The current work
systematically reviews the use of kinesin inhibitors in the medical field. The challenges of KSP and
the practical solutions are also examined, and the outcomes of the previous works are reported. The
significant gaps and shortcomings of the related works are also highlighted, which can be an onset
topic for future works.
usos do Facebook em campanhas eleitorais
Authors: Mezzomo Frank Antonio , Anjos Brandon Lopes dos , Pataro Cristina Satie de Oliveira
Published: January 2024

Esta pesquisa analisa as estratégias de campanhas publicadas nas fanpages do Facebook de candidatos evangélicos que receberam apoio oficial de suas Igrejas na disputa para a Assembleia Legislativa do Paraná, em 2018. Identificamos e coletamos os materiais publicados na mídia social durante o período de campanha eleitoral e construímos categorias temáticas como instrumento de análise, em uma abordagem quali-quantitativa, a fim de observar e comparar singularidades e semelhanças entre as estratégias empregadas no decorrer do pleito. Os resultados apontam para um acionamento intenso da religião em campanha publicizada no Facebook bem como destacam as especificidades do modus operandi entre as instituições religiosas. Há uma série de benefícios concedidos aos candidatos agraciados com o endosso oficial da Igreja, configurando-se como uma estratégia dessas instituições com o objetivo de conquistar espaço na esfera pública, difundir suas referências morais e participar dos jogos de poder que permeiam a sociedade.
Dialética da insularidade
Authors: Bastos Pablo Nabarrete
Published: January 2024

Este artigo parte da reflexão crítica relacionada ao risco de insulamento dos movimentos populares, de suas lutas e da comunitária, popular e alternativa comunicação desenvolvida por eles. Conquanto possibilite potencialmente a participação política e a visibilidade das pautas de interesse popular, esse processo comunicacional é por vezes restrito ao universo cultural e semântico das organizações populares responsáveis por essa comunicação. É objetivo deste artigo contribuir com a compreensão da categoria “hegemonia popular”, mediação teórica e política com potencial para a superação dessa condição de insulamento e encontro com um comum político emancipatório. Metodologicamente, o foco central do artigo é a pesquisa bibliográfica fundamentada na teoria crítica e no método dialético, mas também utilizamos alguns dados de pesquisa empírica que realizamos com redes de organizações populares, a partir de análise documental, para demonstrar alguns esforços para encontrar o comum na luta pela hegemonia popular.
“Well, That’s What She Gets…”: Black Teenage Girls’ Sexual and Reproductive Choice in Young Adult Literature
Authors: Menefee Doricka
Published: January 2024

Using Critical Discourse Analysis (CDA) this article explores the discourse around Black girl sexuality, teenage pregnancy, and teenage motherhood as depicted within Black authored young adult literature.
Return Migration Experiences Portrayed in K-pop Literature: Somewhere Only We Know and Comeback: A K-pop Novel
Authors: Hong Ji Hyun
Published: January 2024

Korean American youth often turn to Korean popular culture, such as K-pop, to claim their cultural space in the U.S., where they are marginalized. These ethnic media influence some to return to their ancestral homeland in search of racial belonging and ethnic identity. Nevertheless, literature and media rarely address the complexities and difficulties of such return migration. Hence, in this study, I utilize two K-pop young adult books—published in the United States, not Korea—to analyze the experiences of return migration and identity negotiation of return migrants in Korea through Korean American K-pop stars and their Korean American love interests.
Feasibility Study on Menstrual Cycles With Fitbit Device (FEMFIT): Prospective Observational Cohort Study
Authors: Lang Anna-Lena , Bruhn Rosa-Lotta , Fehling Maya , Heidenreich Anouk , Reisdorf Jonathan , Khanyaree Ifrah , Henningsen Maike , Remschmidt Cornelius
Published: January 2024

Background

Despite its importance to women’s reproductive health and its impact on women’s daily lives, the menstrual cycle, its regulation, and its impact on health remain poorly understood. As conventional clinical trials rely on infrequent in-person assessments, digital studies with wearable devices enable the collection of longitudinal subjective and objective measures.

Objective

The study aims to explore the technical feasibility of collecting combined wearable and digital questionnaire data and its potential for gaining biological insights into the menstrual cycle.

Methods

This prospective observational cohort study was conducted online over 12 weeks. A total of 42 cisgender women were recruited by their local gynecologist in Berlin, Germany, and given a Fitbit Inspire 2 device and access to a study app with digital questionnaires. Statistical analysis included descriptive statistics on user behavior and retention, as well as a comparative analysis of symptoms from the digital questionnaires with metrics from the sensor devices at different phases of the menstrual cycle.

Results

The average time spent in the study was 63.3 (SD 33.0) days with 9 of the 42 individuals dropping out within 2 weeks of the start of the study. We collected partial data from 114 ovulatory cycles, encompassing 33 participants, and obtained complete data from a total of 50 cycles. Participants reported a total of 2468 symptoms in the daily questionnaires administered during the luteal phase and menses. Despite difficulties with data completeness, the combined questionnaire and sensor data collection was technically feasible and provided interesting biological insights. We observed an increased heart rate in the mid and end luteal phase compared with menses and participants with severe premenstrual syndrome walked substantially fewer steps (average daily steps 10,283, SD 6277) during the luteal phase and menses compared with participants with no or low premenstrual syndrome (mean 11,694, SD 6458).

Conclusions

We demonstrate the feasibility of using an app-based approach to collect combined wearable device and questionnaire data on menstrual cycles. Dropouts in the early weeks of the study indicated that engagement efforts would need to be improved for larger studies. Despite the challenges of collecting wearable data on consecutive days, the data collected provided valuable biological insights, suggesting that the use of questionnaires in conjunction with wearable data may provide a more complete understanding of the menstrual cycle and its impact on daily life. The biological findings should motivate further research into understanding the relationship between the menstrual cycle and objective physiological measurements from sensor devices.
Patients’ Perspectives on the Data Confidentiality, Privacy, and Security of mHealth Apps: Systematic Review
Authors: Alhammad Nasser , Alajlani Mohannad , Abd-alrazaq Alaa , Epiphaniou Gregory , Arvanitis Theodoros
Published: January 2024

Background

Mobile health (mHealth) apps have the potential to enhance health care service delivery. However, concerns regarding patients’ confidentiality, privacy, and security consistently affect the adoption of mHealth apps. Despite this, no review has comprehensively summarized the findings of studies on this subject matter.

Objective

This systematic review aims to investigate patients’ perspectives and awareness of the confidentiality, privacy, and security of the data collected through mHealth apps.

Methods

Using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, a comprehensive literature search was conducted in 3 electronic databases: PubMed, Ovid, and ScienceDirect. All the retrieved articles were screened according to specific inclusion criteria to select relevant articles published between 2014 and 2022.

Results

A total of 33 articles exploring mHealth patients’ perspectives and awareness of data privacy, security, and confidentiality issues and the associated factors were included in this systematic review. Thematic analyses of the retrieved data led to the synthesis of 4 themes: concerns about data privacy, confidentiality, and security; awareness; facilitators and enablers; and associated factors. Patients showed discordant and concordant perspectives regarding data privacy, security, and confidentiality, as well as suggesting approaches to improve the use of mHealth apps (facilitators), such as protection of personal data, ensuring that health status or medical conditions are not mentioned, brief training or education on data security, and assuring data confidentiality and privacy. Similarly, awareness of the subject matter differed across the studies, suggesting the need to improve patients’ awareness of data security and privacy. Older patients, those with a history of experiencing data breaches, and those belonging to the higher-income class were more likely to raise concerns about the data security and privacy of mHealth apps. These concerns were not frequent among patients with higher satisfaction levels and those who perceived the data type to be less sensitive.

Conclusions

Patients expressed diverse views on mHealth apps’ privacy, security, and confidentiality, with some of the issues raised affecting technology use. These findings may assist mHealth app developers and other stakeholders in improving patients’ awareness and adjusting current privacy and security features in mHealth apps to enhance their adoption and use.

Trial Registration

PROSPERO CRD42023456658; https://tinyurl.com/ytnjtmca
Behavior and activity pattern of Minuca osa (Brachyura: Ocypodidae) from Ponuga, Veraguas, Panama
Authors: Lombardo Roberto
Published: January 2024

From November 2022 to February 2023, observations to describe the behavior and the activity pattern of Minuca osa were conducted in Ponuga, Veraguas, Panamanian Pacific. Quadrants (5m²) over four substrate types were also laid and the number and burrow diameter were recorded for density and relative fiddler crab associations to the substrate. Nine discrete behaviors were observed, with feeding and locomotion being the most frequent. There was a significant difference in elapsed time and frequency proportions among behaviors. Combat and waving were male-exclusive behaviors, and more time was spent waving than in combat. Behaviors were displayed non-randomly throughout the observation period with highest frequency between 10:30 a.m. and 12:30 p.m. The sex ratio was skewed towards males (2.4:1), while the carapace width of males and females averaged 23.40 mm and 18.42 mm, respectively. Quadrants covered with Hymenocallis littoralis had the most burrows (20.45 burrows/m2) with the smallest diameter, while the largest diameter burrows were found in mixed-cover quadrants. Maximum temperature and monthly accumulated rain significantly influenced the number of active crabs on the surface.
De aliens y zombis
Authors: Vázquez-López Horacio , Ramírez-Pérez Teresa
Published: January 2024

¿Has visto las películas de Alien o películas de zombis? Resulta, que en el reino animal se presentan ciclos de vida que han servido de inspiración para algunas películas. Y el modo en que se reproduce Alien (o Xenomorfo), o el modo en que se comportan los humanos convertidos en zombis, son tan parecidos a lo que sucede en el ciclo de vida de crustáceos, insectos y moluscos que han sido parasitados. En el caso de los crustáceos, existen algunos que se han especializado para vivir como parásitos dentro de otros crustáceos como cangrejos y camarones, aunque aquí nos limitaremos a platicar de los cangrejos nadadores conocidos comúnmente en México, como “jaibas” (cangrejos del género Callinectes). ¿Recuerdas al abraza caras (facehugger) en la película de Alien el octavo pasajero?, bueno, al parecer quien escribió la película se basó en el ciclo de vida de unos crustáceos muy peculiares conocidos como rhizocéfalos, y estos tienen un cuerpo tan modificado en su estado adulto, que solo parecen una serie de raíces, como las de una planta, y estas sirven para absorber nutrientes del crustáceo al que están parasitando, igual que las raíces de una planta que absorben agua y nutrientes del suelo.
Charales: ¿Qué afecta su sobrevivencia?
Authors: Navarrete Salgado Norma Angélica , Jacobo Segura Dulce Liliana
Published: January 2024

¿Conoces los charales, alguna vez has escuchado hablar de ellos? Bueno, son pequeños peces de la familia Atherinopsidae, tienen importancia biológica, cultural, económica y alimentaria.

Estos amiguitos se caracterizan por presentar una banda plateada a lo largo del cuerpo y en términos de distribución se les encuentra en el centro de la República Mexicana principalmente en los estados de Jalisco, Michoacán y Estado de México.
Determination of chemical composition in Tri-Metal Alloys: a three variable linear equation system approach
Authors: Van-Sertima Ariel , Simmons Sandra , Zablah-Vasquez Raul , Villalta-Cerdas Adrian
Published: January 2024

To enhance the bridge between macroscopic and symbolic representations in chemistry, we crafted a laboratory module focusing on a three-equation system for chemical composition analysis. Students assess the composition of copper, tin, and aluminum alloys by measuring two properties: density and heat capacity. These non-destructive procedures fit within standard laboratory session durations. After gathering data, students tackle three linear equations linking element mass ratio to alloy composition, density, and heat capacity. By pooling data from various samples, the class achieves a comprehensive understanding. This method aligns with objectives for laboratory education, emphasizing scientific reasoning, practical skills, and subject mastery. Students’ results deviated by +/-10% from actual alloy compositions. The discussion of student-gathered data and results supports the feasibility of the laboratory experience for its implementation in introductory chemistry laboratories.
Survey on Bitcoin Price Prediction using Machine Learning
Authors: Mule Vivek
Published: January 2024

Abstract: With the help of specific factors, this effort seeks to improve the present analysis of bitcoin and forecast its price. After conducting a thorough investigation, it was determined which factors all contribute to daily fluctuations in the value of bitcoin. All of the data in this work is made up of various aspects from daily records from the previous few years. The first step in this endeavour is gathering all the data necessary to forecast the price of bitcoin. All of the data was compiled during the previous few years, and it was incorporated into this work. The Recurrent neural network (RNN) algorithm is employed in this work because it provides significantly improved accuracy than earlier techniques. In order for investors to invest in bitcoin easily and for beginners to this market or business, this study forecasts signs of change in the price of the cryptocurrency.
Propagation and shelf-life of weed pathogenic fungi in alternative media and their effectiveness in billygoat (Ageratum conyzoides L)
Authors: Soesanto Loekas , Sastyawan Murti Wisnu Ragil , Manan Abdul , Mugiastuti Endang
Published: January 2024

Control of billygoat (Ageratum conyzoides L) currently uses herbicides, on the other hand, control using pathogenic fungi is environmentally friendly, but for mass propagation and storage, alternative media are needed. The aim of the study was to determine the best type of alternative media for fungal growth and shelf life, as well as its effectiveness against billygoat. The treatment tested involves a combination of two factors: the type of pathogenic fungi (Curvularia lunata or Fusarium oxysporum) and the type of medium (rice washing water or tofu liquid waste). A completely randomized design was used for the in vitro test, while in planta test used a randomized block design with each experimental unit repeated five times. The observed variables were conidia density, number of colonies, incubation period, disease symptoms, disease intensity, and area under the disease progress curve (AUDPC), as well as weed height, number of leaves, fresh and dry shoot, and root weights. The results showed that the conidia density of F. oxysporum was 57% better in rice washing water than in tofu wastewater. The best shelf life for the fungus was four weeks. The use of rice washing water for F. oxysporum and C. lunata effectively delayed the incubation period by 77 and 71% respectively, suppressed disease intensity by 90 and 88%, and AUDPC by 94 and 93% compared to the control. The F. oxysporum grown on rice washing water media was able to reduce the number of leaves, fresh and dry weight of billygoat by 25, 30, and 20% compared to the control, respectively.
Orthonormal bases of extreme quantumness
Authors: Rudziński Marcin , Burchardt Adam , Życzkowski Karol
Published: January 2024

Spin anticoherent states acquired recently a lot of attention as the most "quantum" states. Some coherent and anticoherent spin states are known as optimal quantum rotosensors. In this work, we introduce a measure of quantumness for orthonormal bases of spin states, determined by the average anticoherence of individual vectors and the Wehrl entropy. In this way, we identify the most coherent and most quantum states, which lead to orthogonal measurements of extreme quantumness. Their symmetries can be revealed using the Majorana stellar representation, which provides an intuitive geometrical representation of a pure state by points on a sphere. Results obtained lead to maximally (minimally) entangled bases in the 2j+1 dimensional symmetric subspace of the 22j dimensional space of states of multipartite systems composed of 2j qubits. Some bases found are iso-coherent as they consist of all states of the same degree of spin-coherence.
A Comparative Approach to Sustainable Fish Meal: Prussian carp meal (Carassius gibelio Bloch, 1782)
Authors: Baki Birol , Kaya Öztürk Dilara , Uzun Gören Gülşen
Published: January 2024

In the present study, the usability of Prussian carp (Carassius gibelio) meal (PCM) as an alternative animal protein source in fish feeds was investigated by comparing it with anchovy (Engraulis encrasicholus) and sprat (Sprattus sprattus) meals in terms of their biochemical, fatty acid, amino acid and element compositions. Prussian carp were obtained by fishing and made into a meal (PCM). Anchovy (AM), and sprat (SM) meals were purchased from a commercial company. The amino acid analysis results show that PCM's total, essential, and non-essential amino acid values were lower than that of AM and SM (P < 0.05). The polyunsaturated fatty acids (PUFA) and Omega-6 values of PCM were higher than AM and SM; and lower than saturated fatty acids (SFA), Omega-3, eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), atherogenicity index (AI) values (P < 0.05). According to the element analysis, the P and Ca values of the PCM were higher than the AM and SM (P < 0.05), and the Na, K, Fe, Cu, Zn and Se values were lower. According to the results of the present study, PCM can be utilized in the feed industry to boost the sustainability of fish meals used in feed production, which in turn will reduce the foreign dependency on vegetable and fish meals, and lower feed costs.
Energy Systems Integration: Implications for Public Policy
Authors: Cambini Carlo , Congiu Raffaele , Jamasb Tooraj , Llorca Manuel , Soroush Golnoush
Published: January 2024

Energy Systems Integration (ESI) is an emerging paradigm and at the centre of the EU energy debate. ESI poses significant public policy implications, because, by identifying and exploiting the synergies within and between the sectors, ESI aims to increase flexibility in the energy system, maximize integration of renewable energy and distributed generation, and reduce environmental impact.
Alimentación oral inmediata en pancreatitis aguda: Revisión Sistemática basada en la evidencia actual
Authors: Álvarez-Berrezueta Hernán Ariolfo
Published: January 2024

La pancreatitis aguda es una patología cuyo manejo primario abarca medidas con el fin de asegurar el reposo gastrointestinal, la presente revisión sistemática tiene como fin valorar los beneficios obtenidos tras iniciarse una dieta oral inmediata en pacientes con pancreatitis aguda. Se realizó una revisión sistemática, bajo lineamentos PRISMA, que incluyó ensayos clínicos controlados aleatorizados, la búsqueda fue realizada en PubMed, ScienceDirect y Cochrane, se usaron los términos de búsqueda: “Acute pancreatitis”, “Enteral nutrition” "Oral refeed" y "randomized controlado trial", obteniendo 393 artículos. Tras aplicar criterios de inclusión y exclusión, un total de 6 estudios se incluyeron en la revisión, se valoró: complicaciones o eventos adversos, gravedad del cuadro, requerimiento de analgesia, estancia hospitalaria, tolerancia a la dieta y gastos generados, encontrando beneficios estadísticamente significativos, sobre todo en los últimos tres aspectos. Se concluyó que la alimentación oral inmediata es segura en pacientes con pancreatitis aguda, pese a ello, es imprescindible generar más estudios multicéntricos con el fin de generar evidencia de mayor peso
Aportes de las intervenciones educativas en el manejo del Síndrome Visual Informático: una revisión de literatura
Authors: Silva-Sánchez Diana Carolina , Jiménez-Barbosa Wilson Giovanni , Valero-Pacheco Ivonne Constanza , Gómez-Rúa Natalia Eugenia
Published: January 2024

Objetivo: Identificar intervenciones de educación para la salud que hayan demostrado mejoras en la salud visual y ocular de trabajadores usuarios de computadoras con Síndrome de Visión por Computador. Método: Revisión bibliográfica de artículos originales en español e inglés, publicados entre 2017 y junio de 2022 en las bases de datos PubMed, Scopus, MEDLINE (EBSCO), Redalyc y Ovid. Resultados: De 1.695 artículos, 11 cumplieron con el protocolo. De estos, el 90,90% se publicaron desde 2020 hasta junio de 2022 y la India tuvo el mayor número de publicaciones (27,27%). La mayoría de los estudios fueron experimentales o cuasi-experimentales (36,36%), y para la síntesis cualitativa se clasificaron en intervenciones educativas con tecnología 54,54% (n=6) y las que manejaban educación tradicional 45,45% (n=5). Conclusión: Se demostró que las intervenciones de educación en salud contribuyen a la mejora de la salud visual y ocular de los usuarios de computadora con Síndrome de Visión por Computador. Es necesario investigar y divulgar resultados sobre el tema, que contribuyan a los procesos de promoción de la salud visual y ocular, así como en la prevención del Síndrome de Visión por Computador en el ámbito laboral.
Editorial: Traditional and innovative methods for understanding corporate governance
Authors: Napoli Francesco
Published: January 2024

The latest issue of the journal is composed of papers which are mostly empirical and contribute new ideas to the major issues of corporate governance, such as the appointment of directors, cultural diversity, emerging technologies, managing default risk, managerial discretion, institutional investors and the policy of proxy voting rights, strategic personalities of firms, ownership structure, etc.
Purchase Decision on Products Advertised on Facebook: Insights from Social Impact Theory
Authors:   Department of Data and Information Science Faculty of Multidisciplinary Studies University of Ibadan  Ibadan, Oyo State, Nigeria, Ogunsola Kemi , Mohammed S.B.
Published: January 2024

This study examines Social Impact Theory factors; normative and informational social influences, and social media commitment on the purchase decision of products advertised on Facebook. The study adopts a quantitative survey-based approach, using an online questionnaire administered to 314 postgraduate students from three purposively selected universities in Lagos State, Nigeria (University of Lagos, Lagos State University, and Pan Atlantic University). This study used descriptive statistics to answer three research questions, and regression analysis to test two research hypotheses with the aid of SPSS analytical tool, version 26. Findings revealed that normative social influence, and social media commitment had significant influences on the purchase decision on products advertised on Facebook while informational social influence did not. The study recommends that decision makers in organisations, corporations or companies should encourage Facebook advertisements as an effective communication tool. Keywords: Customers’ purchase decision, E-commerce, Facebook, Internet, Social media CISDI Journal Reference Format Ogunsola K. (Ph.D.) & Mohammed, S.B. (2022): Purchase Decision on Products Advertised on Facebook: Insights from Social Impact Theory. Computing, Information Systems, Development Informatics Journal. Vol 13 No 4, Pp 73-87. Available online at www.isteams.net/cisdijournal. dx.doi.org/10.22624/AIMS/CISDI/V13N4P5
Situational Awareness of Deepfake Technology
Authors:   Department of Computer Science Faculty of Science Imo State University, Owerri, Imo State, Nigeria., Olebara Comfort Chinaza
Published: January 2024

This work is a situational awareness reporting of the deepfake technology, which is a technology where multimedia components such as video. Image or audio of an individual is distorted with the aim of disinforming or misinforming the content viewers. The technology first appeared in November, 2017, when a social media user posted an algorithm that used AI to create fake videos. This paper will discuss areas where deepfake has been applied, some researches of how to create deepfake, and also some researches on how to detect deepfake. The study is mainly to report this new technology thereby making the society aware of its existence and watching out for its use. Keywords: Deepfakes, Awareness, Security, Social Media, Online, Images, Videos, Users, Technology Aims Research Journal Reference Format: Olebara, C.C. (2020): Situational Awareness of Deepfake Technology”. Advances in Multidisciplinary Research Journal. Vol. 6, Pp 153-157. Article DOI: dx.doi.org/10.22624/AIMS/V6N1P14. Available online at www.isteams.net/aimsjournal.
The influences of the US stock market on virtual currency price under us monetary policy threshold
Authors: Yang Tzu-Yi , Lie Eddy , Lu Chien-Chung
Published: January 2024

This study uses a panel smooth transition regression model to investigate the
nonlinear relationship between virtual currency and the stock market under
the US monetary policy threshold from 7 August 2015 to 27 October 2020. A
statistical test showed a threshold effect and confirmed that the
relationship between the US stock market and virtual currency is nonlinear.
Furthermore, virtual currency fluctuation has asymmetric responses to the US
stock market?s fluctuation based on the threshold value. When the federal
fund rate exceeds the threshold value, the changes in the S&P500 with a lag
of one positively affect the fluctuation of virtual currency.
Los matices de la resistencia: Trayectorias vitales de mujeres esclavizadas ante la justicia eclesiástica de Santiago. Chile, siglos XVII y XVIII
Authors:   Universidad de los Andes, Fuentes González Alejandra Cecilia
Published: January 2024

El artículo se pregunta por los usos de la justicia eclesiástica por parte de las mujeres esclavizadas de origen africano, tomando el caso de la Audiencia episcopal de Santiago entre los siglos XVII y XVIII. A través de una metodología de investigación cualitativa, se realiza primero un análisis general de los doce pleitos vinculados con este tipo de mujeres, que hoy conserva el Archivo Histórico del Arzobispado de Santiago. Luego se examinan en detalle los litigios eclesiásticos de Juana Antonia, Teresa y María Josefa, con el fin de describir trayectorias vitales de distintas mujeres y contrastar sus prácticas de resistencia en el marco de una petición judicial. Este ejercicio comparativo permite visibilizar, por un lado, historias en que estas mujeres lograron articular estrategias de resistencia judicial para enfrentar los discursos de poder u obtener su libertad y, por otro, historias donde aquella resistencia quedó sumida entre conflictos sucesorios, ocultaciones y actos de despojo protagonizados por amos y amas. En definitiva, los datos suministrados demuestran los matices de la resistencia en América Hispana y la necesidad apremiante de realizar estudios de casos que puedan enriquecer la interpretación de esta práctica.
“Hágase como parece a la VS”: visitadoras sociales, afectos y feminización en la Justicia de Menores. Chile, 1928-1954
Authors:   Universidad Andrés Bello, Errázuriz Javiera
Published: January 2024

El presente artículo se propone indagar en el papel que jugaron las visitadoras sociales en el proceso de feminización de la Justicia de Menores en Chile, en el periodo 1928-1954. Postulamos que ellas tuvieron un rol clave en este proceso, producto de dos razones: por un lado, sus informes sociales eran insumos cruciales para la toma de decisiones del Tribunal que, la mayoría de las veces, seguía las sugerencias de las visitadoras en cuanto a las medidas de protección a aplicar. Por otro lado, el servicio social era una profesión femenina, que utilizaba herramientas científicas (como el diagnóstico y la visita) pero que, a la vez, destacaba la importancia de los lazos afectivos de los y las menores con su familia y entorno. Este énfasis puesto en los afectos produce también una feminización de la Justicia de Menores. Para demostrar nuestra hipótesis abordamos los discursos sobre la profesión de las mismas visitadoras y revisamos informes sociales contenidos en expedientes del Primer Tribunal de Menores.
Resignificando el liderazgo pedagógico de líderes escolares para favorecer la transformación de sus prácticas directivas
Authors:   Universidad Católica de Temuco, Chaucono Catrinao Juan , Mellado Hernández María Elena
Published: January 2024

El objetivo de este artículo consiste en resignificar las comprensiones del liderazgo pedagógico de líderes escolares para la transformación de sus prácticas directivas de un liceo de la región de La Araucanía, Chile. El trabajo se suscribe a un caso que utiliza una metodologia cualitativa. Participaron un total de 9 personas, distribuidas en 7 docentes, 1 jefe de la Unidad Técnica Pedagógica y 1 director. Para recoger la información, se realizan grupos de discusión, donde el profesorado asumió un rol de coevaluador de las prácticas pedagógicas desarrolladas por los directivos escolares. Asimismo, tanto docentes como directivos utilizan un diario reflexivo, donde registran los aprendizajes construidos en los diversos encuentros formativos. Los resultados señalan prácticas de liderazgo pedagógico de directivos escolares focalizadas en la administración educativa y en monitorear el currículum escolar por medio de la observación de clases. Posterior al diseño e implementación de la propuesta de mejoramiento, se visualiza un cambio en la comprensión de directivos escolares sobre sus prácticas de liderazgo pedagógico. A modo de conclusión, resignificar las comprensiones sobre liderazgo pedagógico de directivos escolares por medio de la coevaluación del profesorado y autoevaluación de directivos escolares favorece las transformaciones de las prácticas.
Josefa Galeote, una hechicera del siglo XIX. Permanencias y continuidades en un juicio inquisitorial
Authors:   Universidad Andrés Bello, Urra Jaque Natalia
Published: January 2024

Josefa Galeote fue enjuiciada por la Inquisición de Toledo en 1801. Su proceso, como tantos otros más, no varió ni se modificó pese a desarrollarse a inicios del siglo XIX. Los folios de su relación de causa describen una serie de situaciones que ilustran las continuidades de un proceso inquisitorial. Es decir, la delación de la testigo, las escrituras del comisario, las cartas e informes enviados al Tribunal, los exámenes de los inquisidores, etc. Nuestro objetivo es analizar el proceso y reinterpretar aquellas características que enfaticen la permanencia y, por supuesto, las continuidades del juicio contra Josefa «la Galeote».
Unveiling the Interplay of Klotho Protein, Chemotherapy-Induced Klotho Protein Deficiency and the Pivotal Role of GLP-1 Agonists like Ozempic in Cancer Survivorship Patient Survival Rate after Chemotherapy Treatment
Authors: Akl Maher Monir
Published: January 2024

Cancer, a pervasive health challenge globally, prompts aggressive treatment measures, with chemotherapy as a primary approach targeting uncontrolled cell growth. While effective against tumors, chemotherapeutic agents, especially alkylating agents, antimetabolites, and other classes, introduce collateral damage to healthy tissues, notably the kidneys. This article explores the intricate impact of chemotherapy on renal proteins and enzymes, particularly the Klotho protein, a key player in aging and longevity. Alkylating agents induce renal toxicity through oxidative stress, affecting Klotho synthesis and antioxidant defenses. Antimetabolites disrupt DNA synthesis, potentially impairing renal function. Antitumor antibiotics, topoisomerase inhibitors, mitotic inhibitors, and hormone therapies each contribute to nephrotoxicity. As Klotho deficiency emerges as a critical factor in the shortened lifespan of cancer patients, the potential role of GLP-1 agonists like Ozempic in stimulating Klotho production is discussed. This dual-action approach could mitigate chemotherapy-induced nephrotoxicity, offering a novel strategy for enhancing the well-being and lifespan of cancer patients.
Tuberculosis in Patients Referred for Liver Transplant: A Case Series and Review of Literature
Authors: P Parikh
Published: January 2024

Pre transplant evaluation of a patient provides unique opportunity to diagnose certain diseases. Tuberculosis is endemic in India and patients are often diagnosed to have tuberculosis during their pre transplant evaluation. As these patients have advanced liver disease diagnosis, treatment planning for anti-tuberculosis therapy and timing the transplant is based on individual choice. There are no established guidelines from either the west or from India. We here report 5 cases of tuberculosis diagnosed as a part of pre transplant evaluation and have summarized available knowledge on managing such patients in peritransplant period.
The Wrong Place at the Wrong Time
Authors: Burnett Bryan R
Published: January 2024

The defendant, Treveon Harris, a known Los Angeles gang member, was wounded twice during the fatal shooting of the victim. The homicide occurred in the mailboxes/laundry room of an apartment complex. Bullet strike angles on a washing machine and the walls of the scene room show there was a struggle for a .40 caliber pistol by the victim and his attacker. The victim lost the struggle for the pistol with two bullets to his head. The victim also received three perforating bullet wounds (unknown caliber) to his legs outside the mailboxes/laundry room. Harris received a ricochet bullet core to his left forearm and had a bracelet shot off his left wrist. Even though Harris was twice wounded when he chanced on the shooting, he was charged and convicted of the homicide. The prosecution presented a shooting scenario that ignored exculpatory evidence. Despite the trial defense attorney being informed of the exculpatory evidence, he refused to present it.
The Importance of Autopsy in Geriatrics
Authors: Chatterjee Sarmishtha
Published: January 2024

Ageing is a ubiquitous biological natural process. Old age should be regarded as a customary, inevitable and biological incidence
Mind Control and Abused-Related Suicide: The Criminal Justice Response to Intimate Partner Violence Against Women in China
Authors: Na Jiang
Published: January 2024

Mind control is a new form of intimate partner violence. It involves the abuser verbally humiliating and intimidating his or her partner in order to increase his or her emotional dependence. The consequences are self-doubt or self-denial on the part of the abused person, fear of resisting the abuser, or even self-mutilation or suicide at the abuser's instigation. Recently, a Chinese court ruled in a case where mind control led to the suicide of his girlfriend, sentencing the defendant, Mu Linhan, to three years and two months in prison for abuse. This case brings the form of violence known as mind control officially into the public view. In this case, the court made a breakthrough in determining that a non-marital cohabitation relationship establishes a family member relationship, and recognized the causality of mind control on suicide. In recent years, China has effectively contributed to the protection of women's rights and interests through the Anti-Domestic Violence Law and criminal law. However, shortcomings in the law limit the ability of rules to combat domestic violence. China should introduce additional criminal law provisions on new forms of domestic violence and improve the scope of criminal law regulation of domestic violence offences.
Undescended Testis Cancer Detected on FDG PET-CT Imaging in a Pediatric Patient
Authors: P Ozcan Kara
Published: January 2024

Cryptorchidism is one of the major risk factors for increased risk of testicle cancer. The differential diagnosis at the inguinal region is very important for hypermetabolic foci because of the possibility of metastasis at this level in cancer patients ongoing PET imaging for detection of metastases. In this case report, the findings of a pediatric patient with inguinal testis cancer identified as primary malignity region on FDG-PET/CT imaging, is presented.
Hypermetabolic Splenomegaly with Infarct in FDG PET/CT: A Clue to Scrub Typhus in PUO
Authors: S Sampath
Published: January 2024

Scrub typhus is a rare zoonotic disease, also being an uncommon cause of fever of unknown origin. In the absence of an eschar, it would be even difficult to diagnose. With recent availability of IgM against scrub tyhus antigen, more cases of scrub typhus are increasingly getting noted. Herewith we report the typical PET/CT findings of Scrub typhus in a patient who presented with jaundice, fever and normal appearing skin.
Living Conditions, Healthy Practice and State of Households of a Town Rural in Colombia
Authors: EAB Marrugo
Published: January 2024

Objective: To determine the hygienic-sanitary conditions of rural houses in a municipality of the Colombian Caribbean zone to identify characteristics and socioeconomic conditions regarding public health. Method: A cross-sectional descriptive epidemiological study was carried out in 32 different dwellings in a rural municipality belonging to the department of Bolívar, located in the northern area of the Department of Bolívar, which, through the application of hygienic-sanitary inspections, sought to determine their current status against as indicated by sectoral and national policies that deal with public health. Within the population of 73,169 inhabitants according to DANE projections, representing 3.4% of the departmental population. The main motivation for the development of this project is based on the fact that almost half of the world's population lacks basic sanitation to protect their environment from human fecal contamination. Building a latrine is the first step on the sanitation ladder in developing countries where the majority of the population defecates in open or public areas. Public health programs to improve sanitation have consistently framed promotional messages in terms of preventing fecal-oral diseases and largely do not motivate changes in sanitation behavior. In this community there are at least 500 families residing for 18 years, with topographic difficulties, but with access to basic public services. Whereas the public health plan proposes projections to improve the health conditions of the population by focusing attention on the most vulnerable groups and applying a comprehensive care model based on the risk approach, continuous improvement of the quality of care and the promotion of participation and social control. Results: The deficiencies found in most of the homes are related to poor lighting elements, the appearance of structural failures and inappropriate habits for cleaning and waste management in general. The findings made in this project will be published in a scientific journal, a book chapter, and a scientific outreach event. Conclusions: Most of the anomalies found, both in houses and access roads, are of a structural nature, facilities, poor waste management and difficulties in the provision of drinking water next to the sectored toilet in green areas. It is very important to be trained and trained in good hygiene practices, deratization, and fumigation and to multiply the information in the younger population of the community about these practices.
Exploring the Ichthyofauna of District Mardan, Khyber Pakhtunkhwa, Pakistan
Authors: Ahmad Ashfaq
Published: January 2024

The current study aimed to investigate the diversity and distribution of freshwater fish in the districts of Mardan, located in the northwest of Khyber Pakhtunkhwa province, Pakistan. Mardan is home to numerous streams and rivers between the Indus and Kabul rivers, making it an important area for fishing and farming. A total of 250 fish samples were collected from February to November 2021. Eight species were identified in Mardan, including Mastacembelus armatus, Gara gotyla, Cyprinus carpio, Puntius ticto, Caraccius auratus, Oreochromis mosambicus, Puntius sophore, and Tor putitora. The results suggest that overfishing and water pollution are major factors affecting the survival and expansion of fish species in the area. To improve the fish populations in the rivers and streams, proper stocking and regulations to control overfishing and pollution are needed. The study found that the Cyprinidae family was the most dominant, with eight species identified in the experimental area. However, the number of Mastacembelidae and Cichlidae was found to be low due to pollution, toxic heavy metals, and other environmental factors that affect breeding and other activities of fish.
Study on Induced Breeding in Oreochromis niloticus (Nile Tilapia) through Hypophysation Technique
Authors: chari T Jagadeeshwara
Published: January 2024

Producing fish to spawn by artificial methods is called induced breeding. Oreochromis niloticus (Nile tilapia) are induced to spawn by the injection of pituitary extract, a process called Hypophysation. Hypophysation is a technique of induced breeding in Oreochromis niloticus by injecting pituitary gland extract. In hypophysation, the pituitary gland extract is injected into intramuscular/pectoral fin region of fish. The gland induces the fish to breed. When the pituitary gland of the same species is used, the hypophysation is called homoplastic. Induced breeding is practised in a wide variety of species, with Hypophysation we can get pure seeds in large number in all seasons. With this technique we can produce hybrid varieties of species. This technique shows high fertilization rate (~85%) and Hatching rate (~80%) this study explodes about procedure and result of hypophysation technique.
Cost and Return Analysis of Fish Farming in Nigeria
Authors: Zanna Babagana
Published: January 2024

The study was conducted in Jere and Konduga Local Government of Borno State, Nigeria. The study concerned with the analysis of cost and return of fish farming in the study area. Data collection for the research work was carried out within the period of thirty-one (31) days from 19th August, to 18th September 2023. Both primary and secondary sources of data were employed. The study revealed fish farming in the study area was favorable as all the fish farmers operates at gain although recommendation was made for the development of fish farming in the study area.
Effect of Natural Preservative (Cinnamon Bark Marinade) on the Microbial Load and Shelf-life of Smoked-dried African Catfish Clarias gariepinus (Burchell, 1822)
Authors: MY Haruna
Published: January 2024

The study was carried out to determine the antimicrobial effect of Cinnamon bark marinade on stored smoke-dried catfish at ambient temperature (37+2°C) for 28 days. The experimental treatments are the control, 0.5%, 1% and 1.5 %( w/v) Cinnamon bark marinade. Thirty-nine fish of average mean weight of 24.87+1.25g were gutted, washed and randomly assigned to the marinade. Thereafter, the fish were soaked in the marinade for 30 minutes and later hot smoked for 12hours. After smoking, the fish were stored in boxes and place on laboratory table for one month. Microbial counts were conducted 7 days’ interval. Three bacterial species namely; Bacillus sp, Corynebacteria sp, and Staphylococcus sp were observed in the study. There was no increase in microbial load as storage progressed. However, the increment was pronounced in control fish sample. 1% Cinnamon barks marinade exhibited the highest 7x103 antibacterial effect. There was increase in microbial load in control sample 25x103 compared to other treatments while 1.5% marinade of the bark treated sample shows potency in bacteria growth. Cinnamon bark marinade could be used because of it antibacterial and antimicrobial properties, therefore protecting stored smoke-dried catfish from microbial spoilage thus limiting economic loss and possible health risk to consumers.