bluuebunny/crossref_metadata_2025 huggingface dataset:
Atlas fotográfico de de alimentos para cuantificar el consumo de alimentos y nutrientes en estudios nutricionales epidemiológicos en Córdoba, Argentina
Authors: Navarro Alicia , Cristaldo Patricia , Díaz María , Eynard Aldo
Published: September 2024

Food pictures are suitable visual tools for quantize food and nutrient consumption avoiding bias due to self-assessments.Objective: To determine the perception of food portion size and to establish the efficacy of food pictures for dietaries assessments. Material and methods: A food frequency questionnaire (FFQ) including 118 food items of daily consumption was applied to 30 adultsrepresentative of Córdoba. Argentina. population. Aniong severa¡ food models (paper maché, plastics) and pictures, thosc which more accuratcly filled the purpose were selected. 3 srnall, median and large standard portion size were determined. Data were evaluated with descripted statistics tools and Chi square adherence test. Results: The asscssment of 51 percent of the food was assayed in concordance with the refercnce size. In general, the remainder was overestimated. Thc 90 percent uf volunteers concluded that the pictures were the best visual resource. Conclusions: The photographic atlas of food is an useful material for quantize the dietary consumption, suitable for many types of dietaries assessments. In concl usion, com parison among pictures of three portions previously standardized for each food is highly recommendable.
Uso del acetabulo expansivo del spotorno en secuela de fractura acetabular
Authors: De Souza Macedo Carlos , Galia Carlos , Cejas Francisco , Sampaio Vieira Jarbas , Storch Keiserman Luciano
Published: September 2024

A series of 14 total hip arthroplasties using the ccmentlesss Spotorno expansivo acetabular cornponent vas perlornied to treatpost traumatie osteoarthrosis that had developecl fc>] lowing an acetahular fracture. 'I'he mean ace of the patients al the time of the arthroplasty was 47 years (range 28-77 ycars). Rey. I'ac. ('mac. Mcd ('úrdoba 57 (1) 81-88 - 2000 This study vas perfarmend hetwecn 1989 to 1999 ( 11 years) , and the mean fa! low-up was 4 years and 9 months. (Tlinical results were evaluated hy,Mene d'Auhigné and Poste] seale, wieh revealed that 78. 501 of the patients presented good and very good results. The radiological evalualion hased on DeLee and Charnlc.y entena demostrated a radio-lucent-lin in 3 patients. According lo the results ohtainedin the series the authors conel Lided thai the traumatic acetabular ostcoarthrosis can be proper]y hanidled with the Spotnrno acetabul ar con-iponent vhen arlhroplastv is indicated.
Análisis de una propuesta para el cambio de paradigma educacional en Bacteriología y Virología médicas, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba
Authors: Marquez Elena , González Silvia , Giayetto Victor , Littvik Ana , Cannistraci Roxana , Jorge Pavan
Published: September 2024

The productivc character of the scienti fic thought pi nts out a niethodological means that mclude the demand of the students'job about the information and not bis mere reception and reproduetion. It is essential to —¡ve the students the opportunity of discovering the cogniti ve processes used ¡ti the production of the scientitic knowledge. In this work, wc present the result oí the Starting of a workshop dynamic in a basic subject, the students' answers, and the analysis of the suhject. In the Chair of Medical Bacteriology and Vuology of the School of Medical Sciences. the National Lniversity of Córdoba 1700 students attencled classes in 1997. The subject was developecl with the aetivitics that worked the sanie contenis from two different learning conceptions: (1)workshop activity, non obligatory, construct i ve. and (IT) theorico-practical activity. ohl i gatory and traditional .Tvv'o voluntary and anonymous interviews were done about the valuation that the student gaye to these two acti vities and their basis, one in the middle and the other at the end of the course. 90,55% classi fied dic traditional activity as positi ve. and 9,457 as negative. Regarcling the workshop activity, the 60,571 classified it as positive and the 39,5% as negative The same developed content with two activities made possible the analysis of the irnpact that the two di fferent inethodologies produced on the students . The student's ans\ver to the traditional activity was hetter than the workshop activity (p <0.001 ). The differences in (he student's acceptance between the two option revealed the niajor difficulty of an alternativc rnethodological strategy in the current educational niode].
Morfología de las células en los tumores moxoides
Authors: Cejas Hugo , Rodríguez Adelaida , Martínez Marcela , Fonseca Mario , Gendelman Héctor
Published: September 2024

We describe a morphologic study of myxoid cells in myxoid tumors or with myxoid regions: myxoid fibrosarcoma, myxoma, myxoid liposarcoma, liposarcoma embryonal rhabdomyosarcoma, chondroma, chondrosarcoma, myxoid leiomyosarcoma, schwannoma, and odontoameloblastoma; and we compare with fibroblasts of umbilical cord, embryonal mesenquima and loose conective tissue in inflamatory conditions. 
Histologic techniques: H-E-PASS, Masson's tichroom, and Del Río Hortegas's panoptic  silver staining.
Histologically Del Río Ortegas's techniques reveals bipolar fibrobasts with loh processes.
Estudio de la relación entre Aflatoxina B1 y Cáncer de pulmón
Authors: Georggiet Omar , Muiño Juan , Montrull Hilda , Brizuela Nilda , Avalos Sebastián , Gómez René
Published: September 2024

The relationship between aflatoxins and liver cancer is well stablished. In addition the inhalation exposure to carcinogen aflatoxin B1 (AFB 1) is considerable. Genotoxic chemical is known to react with DNA either directly of after metabolic activation to form adducts, a step thought to be relevant with respect to chemical carcinogenesis. The presence and the amount of specific DNA adducts provide a good indication of chemical exposure and genetic damage resulting the exposure to carcinogens and account for same of factors affecting individual sisceptibility to cáncer. Analysis de DNA addfucts requires that the sensivity of the methods to be sufficients hight to allow detection of about 1 adduct / 109 normal nuceotides.
Niveles de colesterolemia y de presión arterial. Su relación con diferentes coinfiguraciones de estrés crónico
Authors: Bianco de Juárez Marta , Iglesias Raúl , Scoppa Hilda , Agnelli Héctor , Gauna Héctor
Published: September 2024

Severa¡ experimental studies refer to the relationship betweenchronic stress, cholestero-laemia leveis and variations in the arterial bloodpressure. Our objective is to establish a significant statistical correlation between stress factors, hypertension and hypercholesterolaemiain the studied people. 146 agents were tested among teachers an others employees from the National University of Río Cuarto, who voluntarily went clinical control, reporting data such as arterial pressure, cholesterolaemia, pathologic records; an standized survey wasdone considering potentially stress factors,grouped in fourd different types of stress: (1)-psychoalimentary, (2)-pure psychic, (3)-laboral,(4)-psychofamiliar, giving each of them a value whose addition gane a stress potential factor. The results show that 45.89 % of (he people studied have hypercholesterolaemia (hi gher 200 mg % with a mean 237.09 ± 29.97) being significanthy higher (P=0.001) in the group of employees older than 40 years old., 7.53 % of the people showed high arterial pressure, and the 90.90 % of tterolaemia. The hypercholesterolaemic group showed a marked incidence of stress rates higher, with respect to the total people in the four types of stress studied. Significative higher values were observed in the laboral and familiar stress types coinciding with the hypertense group of individuals. According to the collected data we conclude that the relationship between cholesterolaemia, arteria] pressure and chronicstress vares with the different types of stress considered, and seem adequate index o stressors leveis of studied people.
Retinocoroiditis toxoplasmósicas reactivadas en la pubertad
Authors: Pizzi Hugo , Mafffand Roque , Pizzi Daniel , Páez Rearte Mirtha , Fernández Guillermo
Published: September 2024

By a ci inical-infectious and ophthalmologic examination that includes serologic studies, we found that 17 cases of retinochoroiditisreactivated in the puberty.
Punción aspiración ecoguiada con aguja fina de tiroides (PAEAFT) algoritmo dignóstico
Authors: Irizar María , Spitale Luis , Godoy Graciela , Canga Carlos
Published: September 2024

Fine needle aspiration (PAAF) of thyroid it has demonstrated to he highly sensitive and specific to establish a diagnosis and to implement the corresponding Ireatment, these qualities are increased when the guide ecográfica is uscd: fine needie aspiration ofthyroid with ultrasonography guide (PAEAFT). 139 cases of PAEAFT are presented of whose material was carried out extendedconventional and thin acccrding to specific technique and they were colorcd with Haematoxylin and eosin (H & E) - Tint 15(DIFF- QUIK) and Papanicolaou; analyzing their distribution for sex, age, topography, characteristic of nodules and cytologicdi agnoses.
The presumpti ve diagnoses corresponded to: Multinodular Goiter (21.58%) - Hashimotos thyroiditis (2.87%) -Follicular neoplasm: Under degrce (1-II): (57.57%), High degree (III): 2.15% - liürthle ccli tumors (2.87%) - Papilary carcinoma (4.32%). The prevalence corresponded to the female sex (93.5217c). The pursuit of the patients was caiTied out based on the proposed algorithm, modifiedof that of Gharib, 1997.
Úlcera de Marjolin
Authors: Garzón Gabriel , Burgos Elisa , Grazón Fernando , Cappitelli Lorena , De Caballier Elisa , Caballier Luis
Published: September 2024

Marjolin's ulcers can produce neoplasms. 1'hey appear on previous scars produced by oid three degree burns.Sometimes they appear after 50 years oí' the previous accident. Three patients showing squamous ccliepitheliomas are 1)resented, and the opportunityand technique of the surgical treatment is discussed.
Sinusitis debida a Arcanobacterium haemolyticum
Authors: Notario Rodolfo , Borda Noemí , Gambandé Telma , D'ottori Nilda
Published: September 2024

Arcanobacteriuni haeinolyticum is a bacteria 1 ph ary ng e al pa th o gen t h at predominantl y i nfects adolescenis and youngadults. lt rarely causes severe infection. A case of sinusitis in an 18-year-o1d female patient with a skin rash is presented. The strain was susceptible lo erythromicin, ampicilin, vancomicin, cephalotin, clindamicin, rifanipicin and penicillin. Erythrornicin has been proposed as first-line therapy.
Revisión casuítica de la patología adrenal durante los últimos 23 años
Authors: Vaca María , González Carolina , Vega Ve´ronica , Martínez Marcela , Paradelo Martín
Published: September 2024

Wc present a casuistic revision of adrenal pathology, which was studicd in our service during the period Janaury 1977-July2000. We revicwed 59.069 hiopsies and 2.674 autopsies and we 84 cases. founded with the following findings:Primary tumors 25%Secundary tumors 51%lnfectious diseases 11%Miscellane.ous 12%Unsuitable for diagnosis 1%
Hyperpiasi as, adenomas, pheochromocy-tomas, neuroblastorna, adenocarcinorna are included within primary tumors.The metaslasic tumors corresponded to: lung, pancreas, mammary gland, kidney and carcinomas; endornetrial adenocarcinoma,lymphoma, melanoma, hepatocarcinoma, gastric carcinoma, testicular teratocareinorn a, sk in epydermoid carcinoma, uteruschoriocarcinoma and a primary germinal tumor of the thymus.Within infectious diseases we founded tuberculosis, hystoplasmosis, cryptoeocosis. hydatidosis.Miscellaneous included hematoma, hemorrhage, pseudocyst, Disseniinated Intravascul ar Coagulation (DIC), athrophy, Wegener's granulomatosis, myelolipo[na, hemorrhagic necrosis. There was only one case which was unsuitable for diagnosis due to insuf'ficient material.
Tumores de celulas de la granulosa: Análisis estructural y ultraestructural
Authors: Martellotto Gladys , Frede Silvia , Ortíz Susana , Hliba Ernesto
Published: September 2024

These ovarian neoplasm derive from the ovarian stromal component constituting around the 5 tu 12% of ah ovarian tumors.Objective: To examine the histopathological and ul trastructural morphol ogic characterist ic of the neoplastic ceils and the patognomonic elenient of these tumors: Cali Exner's Bodies
Materiales and inethods: The materials corresponded lo 2 women of 52 and 55 years. The siniomatology was abdominal tumor that went in mercase.The materials were fractioned for the histopathological conventional study and for ultrastructural analysis. For this last one, theywere tixed in Karnovsky, rehix tu osmio and included in Araldita.Resuits: by means uf the different observations it was determined in buth cases the nuclear atipia, indentations nucici and prorninent nucleohi. In one of the cases the presence of Bc,dics of Cahl-Exner vas detecied, and ultrastruciuraly vas compound by whirled fibrils and amorphous material. wiih dense slructures electron tu its around. It was interest the infihirated of plasmatic cells around the tumors celis. These neoplasms are of interesi due to their impredectible hehavicr and lo the hormonal production thai can origi nate ahterations in othcr organs of the genital apparatus.
Las células del sistema inmune accesorio
Authors: Martínez Marcela , Rodríguez Adelaida , Cejas Hugo
Published: September 2024

In the reticulo- Endothelial System (RES9, named at present Accesory Inmune System (AIS), two chieff groups of cells can be recognized:
1- Antigen - presnting cells: Dendritic cells
2- Antigen - processing cells: Macrophages (or Histiocytic cell) 
These cells are wildely disseminated into human organs and tissues: lymphoid organs, blood, liver, endocrine glands, lung, skin, blood vessels, central and peripheral nervous systems (CNS and PNS), placenta. kidney, and soft tissues.
Dendritics cells and macrophages can be observed in tissues with silver impregnation technique of Del Río Hortega - Polak, or with multiple specific immunohistochemical stains.
The origin of macropage / monocyte is from common pluripoyencial bone marrow progenitor cell, with susequently stages of maturation:
Colony - Forming Units (CFU-S), Colony- Forming Units of Granulocyte / Macrophage (CFU-G/M), Colony - Forming Units of Macrophages/ Monocytes. 
The origin of dentritic cells is heterogenous. Their lineage is from the same bone marrow precursors of macrophages/ monocytes, but there are recent evidences that also may have a lymphoid origin.
Macrophages play important roles in: 1- Phagocytosis. 2- Natural Immunity. 3- Secretion of Cytokines. 4- Antigen presentation. The primary function of dentritic cells is the presentation of antigen and activation of T lymphocytes. 
Nonmalignant reactive disorders and true malignant neoplasms of macrophages and dentritic cells, have been actually reviewed.
Between the main entities of these groups there are:
1- Nonmalignant reactive macrophages disorders: Hemophagocytic Syndromes. Sinus Histiocytosis with Massive Lymphadenopathy (Rosai- Dorfman disease) 
And nonmalignant reactive Langerhans cells disorders: Langehans's - cell Histiocytosis (Histiocytosis X)
2- True malignant Histiocytic Sarcoma (Reticulum cell Sarcoma). Malignant Histiocytosis. Microglioma of CNS
3- True Malignant neoplasm of dentritic cells: Folicular Dentritic Cell Sarcoma and Interdigitating Dentritic Cell Sarcoma. 
True malignant Langerhans cell neoplasm has not been yet clearly demonstrated.
Finally, it is important to note that marcrophages and dentritic cells are commonly observed as reactive cells in numerous malignant tomors (carsinomas, sarcomas, lymphomas, etc) However, their precise role has yet to be determined.
Decidua en la superficie peritoneal imitando nódulos metastásicos. Hallazgos durante una intervención cesárea
Authors: Piccinni Daniel
Published: September 2024

The occurrence of cctopic decidua has been observed rnost often in the ovaries, uterus, and cervix. A peritoneal localization is less frequent and usually an asymptomatic incidental finding. Ectopic decidua was investigated in biopsies taken during cesarean sections, electíve tubal ligations, appendectomy and in tubal pregnancies. ITistologic studies have been carried out of fragments from the epiploon, appendiceal serosa, tubal serosa, retroperitoneal lymph nodes and various abdominal organs. Our purpose is to report a case of peritoneal deciduosis in a 46-year-o1d woman, asymptomatic, discovered during cesarean section and rniniicking metastatic nodules (in- cidental linding). The histopathological diag- nosis was done based on specimen studied with the common technique of paraffin embcdding and hematoxilin - eosin staining. Wc believe that this decidual transformation of the peritoneurn arises from a pro gesterone-induced metaplasia of the coelomic stroma, being often a totally reversible phenomenon.
Linfoma de células NK/T Extranodal tipo nasal
Authors: Kurpis María , Diller Ana , Calafat Patricia , Ruíz Lascano Alejandro
Published: September 2024

The vast majority of Iymphoma occurring in the testis are diffuse large B-cell Lyrnphoma. Wc report on a case of natural killeríT ccli lymphoma in a forty four ycar oid male, with bilateral testicular and cutaneous invoivement with a highly aggressive course.The tumor celis were positive for hoth CD56 and Epstein Barr Virus, encoded EBER molecules, and showed focal angiocentricgrowth thus fullfiling the entena for NK/T ccli lymphoma of nasa! type. Dermatopalhologists and uropathologists should be aware of this rare entity vic may only be diagnosed after extensive inrnunohistochemical studies.
Odontoameloblastoma (AGUAFUERTE AGUATINTA)
Authors: Marcó del Pont Celia
Published: September 2024

Una muestra microscópica de un tejido orgánico puede poseer un valor preciso para quien en un laboratorio se halla investigando. El científico a cargo de esta tarea utiliza una información específica, y lo que está viendo le devuelve una cantidad de datos dentro de su disciplina que le ayudan en su trabajo. Ahora bien, este profesional tomó una serie de foto graffas de las muestras que estuvo analizando, y estas fotografías son observadas luego fuera del laboratorio por otra persona, que no maneja el mismo código que nuestro investigador Fuera de contexto, el expectador puede deducir de que se trata, pero ya no dentro de una rigurosidad científica, sino que aparecen otros elementos. El expectador asoció las formas de las células con texturas, y los filamentos conlíneas, por lo que han dejado de ser filamentos y células para transformarse en otra representación. Por lo tanto, nuestro expectador ha creado un universo diferente a partir de lo que está viendo, e imaginó galaxias, paisajes, entre otras cosas. En definitiva se ha apropiadode una parte de la realidad para transformarla en otra obra abstracta en su mente.
Esto que ha aparecido de la mente, estimula la concepción de una obra plástica (un grabado). Ysus variantes en el color, la forma, el tamaño, la textura, etc., fuera ya de la imitación directa del material original (que fue el disparador de la concreción de la obra), si bien guarda alguna relación con éste, nos muestra otra realidad.
Con este pequeño relato quisimos ejemplificar cómo se llegó a la realización de los grabados que se muestran en este número, a partir de las técnicas que desarrolla la Cátedra de Grabados de la Escuela de Artes, en este caso un aguafuerte aguatinta.
Tumores estromales gastrointestinales: Evolución conceptual.
Authors: Fonseca Ismael B , Spitale Luis S , Gramática Luis , Cejas Hugo , Piccinni Daniel J , Ghirardi Graciela
Published: September 2024

Gastrointestinal strornal tumors (GISTs) constitute the largest category of primary noncpithelial neoplasms of the stomach ancl small bowel. They represent about 1-2% from all neoplasrns of the digestive tract. They occur most commonly in the stomach and small bowel, but small series of comparable tumors havc also been reported in all the other parts of the tubular gastrointestinal tract, inclucling esophagus. colon, rectum and amis. They can also involve omcntum, mesentery, uterus, retroperitoneum. mesocolon and soft tissucs. Originally recognized ¡u 1960 by Martin ct. al. as a clist.inctive type of stromal neoplasm of the bowel, they were subsequently reported by Stout. vlio introduced the term leiomyoblastorna. Because of difficulties ¡u accurately predicting the biologic behavior of these tuniors, the terrn "smooth muscle tumor of uncertain nialignant potential" (SMT- !JMP) has heen introduced for borderline tumors. In 1983. Mazur and Clark comed the terrn gastrointestinal stronial tumor and suggested that these neoplasias might arise from (he inyenteric nervous system. Sorne studies have reported evidence of neuronal cell clifferentiation ¡o a proportion of GISTs and the terrn 'gastrointestinal autonomic nerve tumor (GANT) has been introduced. Kindblorn et al are providing cogeni arguments to suggcst that GISTs show difíerentiation toward ¡nterstitiat Cajal celis (pacemaker celis of the gastrointestinal tracl). lnmnunohistochemically the GISTs often reveal lnmunoreactivity for vimentin. CD34 and CD! 17. Tlie airn of this paper is to perforrim and analysis of the historie evolution ami conceptual of the GISTs
Cotilo expansivo CLS. Resultado a 10 años
Authors: Modrego Francisco , Molina Juan
Published: September 2024

Thc CLS:t acelabular cup, is a Ii cmi sph crica], sel f-expand ing cementless cup. The CLS® cup initial stabili(v is achievecl by expansion-shell. Secondary the bone, which grows o:: (he surface of (he titanium, ayer (he durable stability. Wc report a relrospective study of 26 CLS eups .The mean follow-up was 134 nionths. Clinical results were evaluated by Merle d'Aubignc scale, witch revealed that 96% of the patients presented good oc excellent results. Racliologically, 100% of cup showed siable fixation by bony without signs of ascptic loosening ir: al] palients.
Estudio genético de hipoacusia en familias de Argentina
Authors: Reynoso Raúl , Hendl Silvia , Berteik María , Carlos Curet , Nicemboin Luis , Moreno Barral José , Rodriguez Ballesteros Montserrat , Del Castillo Ignacio , Moreno Felipe
Published: September 2024

Rccenl advances in molecular genetics as wcll as iniproved stratcgies for ihe prevention and control of non-syndromic hearing loss (NSHL) have contributed to the rising importance of their inherited causes. In this studv we report 32 families from Argentine with one (sporadic) or i'nore (faniilial) individuals affectcd. Al] the families were initially screcned for mutations in three autosomal nuclear genes and one mutation in mitochondrial DNA. These genes have been found in a great number of familial or sporaclic cases of congenital dcafness in Caucasians. The mutant allele 35 del G of connexin 26 (GJB2, locus DFN131 on 13q12) was preseni in three families. Wc have irivestigated the gene encocling otoferlin (OTOF, locus DFNB9 on 2p22-1)23) and we found the Q829X mutatiori in helcrocigositv in iwo families. Wc have also identified in heterocigosity the 342-kb dcletion of connexin 30 (GJB6, locus DFN131 on 13q12) in une family. Oil thc other hand. we have not found any paticnt with niitochonclrial niutation. Since the screening for other inutations is very expensive, our main goal is to irivestigate the most frequent mutations in each separate gene in the argentine population and to develop simple and specific tests for each frequent rnutations.
Estudio morfológico - infomático de las estenosis de las arterias femorales humanas para su aplicación como complemento diagnóstico
Authors: Miguel Juan , Mattara Mario , Ponso Ricardo , Idelshon Sebastian , D' Otavvio Octavio
Published: September 2024

l'his paper studies the performance of the blood flow starting from stenotic human adult femoral arteries with different grades of obstruction, removed from autopstes and surgical arnputations, and from simulations produeed by an original simulator computerized software haseci on the method of finite elenierits for newtonian, homogeneous ancl uncompressible fluids. Its employment generated numerous maxirnal curves, subsequentiv joined in a unique graphic of easy application. Exeeeding the evaluation of the origin and impact of turbulences by analvzing the different variables involveci in such anomalous conditions (i.e: prcssurc. velocity field and stress tensor). the results here reported niay constitute a useful complementary diagnostic meLhod together the others used al present.
Olvido de los contenidos de histología en alumnos de medicina
Authors: Bassan Norberto D , Vinuesa Miguel A , Soldano Oraldo R , Di Sipio Agustina , Venezia Sebastián
Published: September 2024

Memory: ability to record, file, classify and later recover of information., essential In processing information and learning, In analogy with a cornputer. Forgetfulness: failure to transfer information from short term rnernory to long term memory  or to recover information from the latter. Aim: to study forgetfulness in contents of Histology in students one and halfyear aíter regular course. To evaluate leve] of re-utilization of contents in second and third year courses. Students with high  performance ¡u 2002 (n=26) were evaluated with 20 cytology and histology questions and 20 questions related to organs.  20 inultiple choice and 20 brief filled answers were useci, expressing the level of usefulness of the contents in Physiology  aun Physicochemistry, and in the first quarter of Pathology, Microbiology and Pharmacology. The performance of 2002  course was  compared with the current test, results of cytology and histology questions versus organs ones and multiple  chotee answers versus brief filled answers. The loss was in the order of 50% in the recovery of contents (37.07 ± 1,76 = 92,6%vs. 18,52 ± 4,33 = 46,3%)without difference between cytology and histology versus organs neither among multiple choice answers versus brief filled answers. The highest usefulness in the contents refers to Pathology (69%) and  Physiology (50%) and the lcsser to Physico- Chemistry.(7%) We estímate that forgetfulness in our students would have  been even higher without the employnient of active techniques of learning.
Cáncer de Mama: alcances actuales y vigencia de la exploración estadificatoria extrapleural de la cadena mamaria interna
Authors: Del Castillo René A , Garello Néstor C , Kuschnir Emilio , Castro Ricardo
Published: September 2024

The interest to know the lnternal Marnmary Chain (IMC) Involvement is that it is a  lyrnphatic filter as primary as the axilla. Anatomic-surgical fundamcnts, were presented for   thcir exploration .Fifty (50) pectus-sternal, analizing the number of nodes (average 9,7 per  pecirnen), located preferably in the three first intercostals spaces, were studied. In the  second phase IMC with a staging criterion and extrapleural way, resecting 1 or 2 costal  cartilages, were explored. In 78 patients, pathological-anatomy correlation between IMC  and the axilla, we observed 6% positive IMC with negative axilla. More recently in the era  of the sentinel node, we have explored IMC in 44 patients through intercostal spaces and  without cartilages resection. lo 28 patients we performed through radioisotopic way and gamma probe and in the remaining 16, through anatomic search !f the tumor was either  upper mid or lower. The most frequent spaces explored were in the 2- and 3: 2.27 nodes  average per patient. The pathological-anatomy between IMC and the axilla revealed the  foliowing results: axilla (-) IM (-): 59%; axilla (+) MI (-): 25%; axilla (+) IM (+): 11% and  axilla (-)IM (+): 5%. Wc concluded that this is a non - aggressivc method, with an  exccllent tolerance that aliows the evaluation of another filter as primary as the axilla aoci that together they represent the hest systemic disease prognostics. We believe that its  exploration is justified in those cases in which the histological result , correlated with the axilla, aliows a therapeutic approach change.
Características de los pacientes internados con alimentación enteral de un servicio de clínica médica
Authors: Belletti Gerardo A , Gómez Jaime , Yorio Marcelo A
Published: September 2024

BACKGROUND: When a patient is unable to swallow enough calores by mouth and has  his digestive tube working normally, the Enteral Nutrition (EN) is prescribed. Our aims was identify the patient who requires EN by sounding at Clinical Medical admission. METHODS: From 11/2001 to 11/ 2002; 331 patients were attended in cornrnon rooms. 50  of them (15%) required EN. Retrospective descriptive study was made, evaluatlng: dernographic data, diagnoses, comorbilities, self-validity, staying, nosocornial  complications, studies, medicaments, inter-consulting and mortality as well. RESULTS: In  50 patients under EN, 56 % were men, with an age rate of 65 years Standar Error (SE) 2.37  and daily life activity rnecllurn rate was 2 (SE) 0.35. Diagnoses at admission: Strocke 22%,  acute pneurnonia of community 22%, pneurnonia by bronchoaspiration 10%, acute  confusional syndrorne 10%, etc.. Comorbilities: 54% presented 3 or more concurrent  diseases, Hypertension 60 %. Dernentia 28%, type 2 Diabetes and strocke 26%, iskemic  cardiopathy 14%. etc. Adrnission time rate: 6 days (SE) 2.02, staying at intensive care unit  40%. Nosocomial compllcations carne up in 34%, 76% ACS, 11.7% urinary tract infection,  pneumnonia and enclovascular infection 1 each. 4 labs were required in rate (SE) 1. 14, and  3 cornplernentary studies per patient (SE) of 0.24. In arnbulatory treatment they used 3  drugs as an average (SE) 0.37. The highest prescription day approached 7 as average (SE)  of 0.61. At discharge they left with an average of 4 (SE) 0.39. In every case kinesiotherapy  and phonoaudiology were used as well. Ther was lnterconsulting regardirig lnfectology in  24%, general surgery 16%. Mortality 22%. CONCLUSION: EN is usual in clinical  admission. It regards an elderly patient with lacking self-validity, who oven 50% of cases  presents more than three cornorbilities (mnostly hypertension). Facts of admission usually  registered: neurological pathologies and infectioris. Adrnission length was the sarne as  general settlers. Alrnost half of them needed intensive care assistance. Nosocomial cornpllcations are usually found. They are patients who require many drugs at home, while  admitted and discharge time as well. lii every one kinesiotherapyand phonoaudiology were  applied. Mortality raised high. Unable chance to use commercial diets was not a trouble to feed them.
Detección de hipertensión arterial en niños en edad escolar
Authors: Dumas Luciana , López Cross Sergio , Peroni Daniela , Valenzuela Gabriela
Published: September 2024

INTRODUCTION: Hypertension is a inultifactorial desease, with increasingiy incidence and prevalence, that ¡s why it is considered a public health issue. OBJECTIVES: To know the prevalence of hypertension in children from 6 to 12 years old, in Cipolletti city. To check if there are differences as regards sex and age. To institutionalizalice blood pressure messurement as part of the rutinary physical examination in the control of a child METHODS AND MATERIALS: This vas a cross sectional study. Blood pressure readings were obteined from 1038 students aged between 6 and 12 years oid: who belong to 7 public schools of Cipolletti. Mercury sphyngomanometer and cuffs of 7.5 per 15 cm and 12 per 22 cm were used. The auscultatory rnethod was used in phase 1 and y of Korotkoff. The second Task Force recomendations for blood pressure in children were followecl. Blood pressure readings were obteined in 3 visits. Those students who had blood pressure messurement iqual to or higher than those established for hypertension were identified during each visit: boys 115/ 75 mmHg (6-8 years) 118/79 mmHg (9-10 years) and 122/80 mmHg (11-12 yars) girls 113/ 74 mmHg ( 6-8 years) 118/79 mmHg ( 9-10 years) and 122/79 mmHg 11-12). RESULTS: The prevalence of hypertension is 3.37%, being more frecuent in the range of ages that go from between 6 to 8 years, which corresponds to a 74.29% of the hypertcnsed children. The hypertense group messurements of blood pressure are: a)Boys: 122.92 mmHg ± 4.11/78.43mmHg ± 5.19; b)Girls: 123.63 mmHg ± 7.43/80.22mmHg ± 2. There were not significant differences between sexs atthe 5% (a=0.05) leve). The blood pressure has never been messurered to 597 students (58%). CONCLUTIONS: The prevalence of hypertension jo Cipolletti is similar to international statistics. There is a number of children with hypertension that is not detectecl during medical examination dije to lack of blood pressure mncssurement institutionalization.
Citoqueratinas 7 y 20 en el esófago de Barrett
Authors: Arra Antonio , Nieva Norma , Rey Natividad , Fernández Ángel
Published: September 2024

TRABAJOS DE ACTUALIZACIÓN CITOQUERATINAS 7 Y 20 EN EL ESÓFAGO DE BARRETT CYTOKERATINA 7 AND 20 IN BARRETT'S ESOPHAGUS Dres. Antonio Arra, Norma B. Nieva, Natividad Rey, Angel O. Fernández Servicio de Patología Hospital Escuela de la Universidad Abierta Interamericana. Quimo 91 811 A (1406) Floresta. Capital Federal. Tel/fax: 011 4612 6209 - aarra@intrarned.net.ar ABSTRACT Barrett's esophagus (BE) has been identified as the niost important risk factor for adenocarcinoma of the distal esophagus. BE has been categorized as long-segment (LSBE) if it extends 3 cm or more up the esophagus and as short-segrnent (SSBE) if it extends less than 3 cm unto esophagus. Intestinal metaplasia may also develop in gastric mucosa (IMG) at the gastroesophagealjunction. IMG has a much lower risk to progress to dysplasia or carcinoma when compared with SLBE or SSBE. Moreover, these conditions are difficult to distinguish one from another only based on endoscopic and morphologic criteria. Therefore the aún this study was to evaluate the cytokeratin (CK) 7 and 20 inmnunoreactivity patterns in these intestinal metaplasias with the purpose to determine the precise anatomic site of the biopsy. Biopsy specimens from 14 patients with LSBE, 6 with SSBE and 7 patients with ¡MG were inrnunohistochemically stained with monoclonal antibodies to CK 7 and 20. Barrett's CK7/20 pattern was characterized by superficial and deep CK7 reactivity and only superficial CK 20 staining in the intestinalized mucosa. This pattern was found in all 7 (100%) patients with LSBE, and was absent III all 7 patients with IMG. AII biopsy specimens from patients with IMG showed no staining for CK7 and diffuse surface positivity for CK20. 67% of the biopsy specimens from patients with endoscopic SSBE showed Barrett's CK7/20 pattern, and the remaining 33% specimens showed the IMG staining pattern. Based en our data the inmunohistochemical determination of CK7/20 is an excelent tool with high specificity in distinguishing LSBE and SSBE from IMG.
Incompletitud y Medicina
Authors: Cuestas Eduardo
Published: September 2024

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Harvard, histórica presentación de la anestesia en el arte
Authors: Roqué Molina Martín , Roqué Carmen María , Roqué Martín H (Hijo)
Published: September 2024

This article is about the use of ether as ageneral anesthetic that was usecl for the firsttime by T. Morton at Harvard University. Itwasa landmark in future surgical procedures andthis discovery was documented by the paintingof the Robert Hinckey and it has been used forteaching history of medicine.
Prevalencia de hipertensión arterial y factores de riesgo asociados en el departamento Sobremonte y Sur del departamento Ojo de Agua
Authors: Pedraza Antonio , Camino Willhuber Gastón , Chaile Iván
Published: September 2024

Arterial Hypertension (AH) is a disease with multiple risk factors (RF), and it is one of the most important risk factor for cardiovascular diseases. The objective of this study was to determine the prevalence of AH in Sobremonte area and its correlation to other risk factors. The study was done in an special programme called “ Solidarity in Health” (SIH) supported by the College of Medicine at the National University of Córdoba, which provided primary care to residents of Cachi Yaco (Sobremonte Department). It is an small village near Santiago del Estero province located in 226 km from Córdoba city. They went to the city and they examined the patients at the the “French and Berutti” school for nine consecutive years (2000-2008). Sobremonte area is the poorest deparment in the province of Córdoba and it has the highest rate of lowest socio-economic development, and a very deficient health care system. . The only hospital providing primary care is in San Francisco del Chañar, and the access is not free. The study involved the determination of the arterial pressure (AP) according to the seventh “JNC”criteria , body mass index (BMI), levels of alcohol consumption, exercise, salt consumption, diabetes and smoking in all the patients. Additionally, three water samples from different representative zones were collected and tested for sodium concentration. 471 patients were included. The incidence of AH was 43.5% of the patients. (51% men and 36% women). Higher incidence of AH was found in patients between 50 and 59 years old. There was a stadistical difference in the BMI, diabetes, and alcohol consumption between healthy patients and patients with AH. There was not any correlation between AH and exercise. We found higher levels of sodium in the water of this area and it was between 13-35 higher than in Córdoba city and it was correlated with AH. We conclude that the increased sodium consumption is one of the most important risk factor of AH in this population.
Linfoma plasmocitoide de intestino delgado. Presentación Clínica con un cuadro de abdomen agudo
Authors: Kaplan R. , Burgos A. , Rodriguez N. , Meza Vetanzo Z. , Ortiz S. , Piccinni DJ.
Published: September 2024

Primary tumors of the small intestine are rare; 15-20% of the cases are extranodal lymphomas from B or T cells. Higher Incidence occurs in patients between 21 and 50 years. The clinical symptoms are pain, intestinal obstruction, diarrhea, bleeding or perforated peritonitis. In high-grade lymphomas, the cells are large and pleomorphic, with immunoblastic and plasmacytoid features, and immunopositive for alpha chain immunoglobulins. We reported the case of a 56-year-old patient presented with abdominal pain associated with intestinal perforation. Resections of a 9-centimetres-long segment in the small intestine was performed, which was covered by purulent plaques, with a perforation of 5 mm, surrounded by a greyish-white thick intestinal wall. It can be observed in the microscopy a proliferation of neoplastic cells arranged diffusely and with frequent mitosis. Large areas of immunoblastic and plasmacytoid configuration were evident. The immunomarcation was consistent with a lymphoma of large cells, immunophenotype B, with plasmacytoid development. We highlighted the clinical presentation like acute abdominal pain and its clinical and pathological characteristics, especially in the plasmacytoid development that should differ of the true plasmocytoma.
Loxoscelismo cutáneo-viscero-hemolítico con fallo renal agudo
Authors: Alfaro Flavia V. , Dotto Beatriz H. , Sesin Ana M. , Prettini Viviana , Sesin Jorge , Aliciardi Enrique , Vergottini Juan C. , Gonzalez Mauricio
Published: September 2024

The Loxoscelism is caused by the bite of spider Loxosceles laeta gender, of worldwide distribution. The poisoning can cause lesions dermonecrotic and less frequently a systemic illness that can be fatal.The mechanism of venom action is multifactorial. The characteristic dermonecrotic lesion results from the direct effects of the venom on the celular and basal membrane components , as well as the extracelular matrix.The initial interaction between the poison and tissues, causes complement activation , migration of polymorphic neutrophils, liberation of proteolytic enzymes, cytoquines, aggregation platelet, and blood flow alterations that result in edema and ischemia, with development of necrosis. There is no a definitive treatment for loxoscelism. However, the value of specific antivenom, to decrease lesion size and limit systemic illness even when such administration is delayed. We present a case of cutaneous-visceral loxoscelismo with unfavorable evolution.
Acreditación y calidad de los programas de formación profesional en medicina
Authors: Yorio Marcelo A.
Published: September 2024

Quality in higher education is a major concern in virtually every country in the world. Many factors explain it: the diversification of institutions, competition among them to win over students, changes in the way knowledge is produced, interest in safeguarding the level and relevance of learning, the requirements of globalization, the need to standardize conditions in the new regions created, and the meaning and suitability of studies are among the most outstanding.
Características clínicas y tilt test de pacientes con sospecha de sincope vasovagal
Authors: Contreras Alejandro E. , Morillo David A. , Brenna Eduardo J. , Bagur Rodrigo H. , Caeiro Andrés A.
Published: September 2024

Background: Vasovagal syncope is the most common cause of syncope and is an amount medical, social and economic problem.Material and methods: We study a population of patients with history of syncope of presumed vasovagal origin submitted to head-up tilt test (TT) with intention to describe and to compare symptoms, signs and trigger situations between positive and negative TT. Twenthy four variables were investigated (chosen according to the clinical experience). Results: One hundred thirteen patients were included. The age mean was 33,3 ±19,4 years and 67.3% corresponded to women. Eigthy one patients (71,7%) experienced syncope during test. The more frequent response was mixed subtype (58%), followed by vasodepressor response (30,9%) and cardioinhibitory response (11,1%). There were not significant differences between both groups in symptoms, signs and trigger situations. In patients with negative TT was more frecuent syncopes triggered by extreme exercise (p = 0,012).Conclusion: In patients with vasovagal syncope suspicion, a clinic history does not predict TT results.
Aplicación del portfolio en la enseñanza de clínica dermatológica: una experiencia en didáctica de la medicina
Authors: D. de Cabalier María E. , Chalub Delia M.
Published: September 2024

We present a learning experience conducted in the Chair of Dermatology Clinic of the Faculty of Medical Sciences, National University of Cordoba in the context of curriculum change. For comprehension, present a theoretical framework and practical from the conceptualization of the "portfolio" teaching and its role teaching and learning paradigms sustained constructivist medical education. The portfolio Teaching is not a collection of papers, but a coherent set of experiences led thoughtful learning between teachers and students. This resource allows to account for the "qualitative achievements" of students from their work produced, sorted and evaluated in a carefully planned sequence of experiences and case Dermatology Clinic. To introduce the teaching portfolio, the planned new student grouping shapes and a sequence of learning experiences for the construction of this resource, namely: "The development of theoretical material iconographic resources and working guidelines for students. "The clinical reasoning on a case or laboratory experience-Clinical case Discussion and bibliography. -The development of records to from observation of patients. "The study of clinical cases: diagnosis and evolution of clinical cases. Interconsultations-Registration and referrals. "The magazine room and sharing experiences. In each of these, production, tutorial feedback Team teaching and assessment tasks allowed assessment approach to learning and improving he achievements of the students to the approval of the subject.
Déficit de vitamina D y osteoporosis en una población rural de montaña en Córdoba – Argentina
Authors: Gobbi C. , Salica D. , Pepe G. , Petenian E. , Dotto G. , Martinez F.
Published: September 2024

Introduction: Vitamin D deficiency is defined when blood levels of 25-hydroxyvitamin D (25 (OH) D) is less than 20 ng / mmol/L. The status of Vitamin D level is associated with clinical, pathological and physiological changes as increased of parathyroid hormone, bone remodeling, osteoporosis and increased risk of fractures. Moreover, vitamin D and its metabolites are known to be associated with multiple chronic diseases as diabetes mellitus, autoimmune, cardiovascular and neoplasia diseases. Objective: To assess the vitamin D status in a rural population of Córdoba Province in Argentina and its relation with bone mineral density. Material and Methods: We prospectively studied 31 patients over 50 years old who live in a rural population of Pampa de Achala in Córdoba Province, Argentina. This city is located in Córdoba High mountains. Blood vitamin D levels were tested in 24 patients and Bone mineral density in 31 patients. Vitamin D level was determined by HPLC. The vitamin D level were considered normal between 20-50 ng/ml in the winter season and 20-80 ng/ml in the summer season. Bone mineral density of lumbar spine and femoral neck was measured by DXA GE LUNAR DPX-L, according to World Health organization classification (37). The data were analyzed by Spearman coeficient and Chi cuadrado.Results: The vitamin D levels samples were avaliable in 24 patients. Mean blood Vitamin D level was 24.54 ng /ml. 8 of them (33%) had vitamin D level less than 20ng/ ml. 83% (20) of the analysed patients had vitamin D level less than 30 ng/ml and only 4 patients has vitamin D level more than 30 ng/ml.Low bone mineral density of lumbar spine and femoral neck was found in 66 % of the patients. 19 % of the patients were diagnosed of lumbar spine and femoral neck osteoporosis and 29% of them had lumbar spine meanwhile 25% had femoral neck. There was not statistically significant associaton between vitamin D level and bone mineral density analysed by Chi Cuadrado (p<0.07). A significant association was found between blood vitamin D level and low bone mineral density of femoral neck (Spearman 0.51) Conclusions: Vitamin D insufficiency is high in the rural adult population of Pampa de Achala in Córdoba and it could be a major health problem in this population.
Neumonías en pacientes con gripe
Authors: Tarán Mariana , Igarzabal Pablo , Bergallo Carlos , Riera Fernando
Published: September 2024

In March 2009, there was an outbreak of respiratory illness, later identified as caused by Influenza A (H1N1); the affected patients can develop severe lower respiratory infections. Objective: To describe the characteristics of 14 patients admitted to Hospital Córdoba diagnosed with H1N1 Influenza-associated pneumonia during July and August of 2009. Material and Methods: We analyzed patients admitted between 26/06/09 and 08/09/2009 with diagnosis of community-acquired pneumonia. All patients were conducted laboratory, chest X-ray, blood and nasal swab for viral isolation by polymerase chain reaction (real-time RT-PCR), beginning treatment with sulbactam ampicillin, clarithromycin, and oseltamivir. Results: The number of patients studied was 44 patients, in 14 patients was confirmed the diagnosis of influenza by RT-PCR, the median age was 44 years (range 18 to 81 years) and 9 (64%) were female. The average time between onset of symptoms and medical consultation was 5 days and the average hospital stay was 6 days. Clinical symptoms: fever over 38 C, 13 patients (92%), dry cough, 4 patients (28%), productive cough, 9 (64%), headache and myalgia: 6. Radiological presentation 10 (72%) patients had bilateral involvement, both bases, and two or more quadrants involved in the chest X-ray. Co morbilities: one patient had heart disease and one patient had COPD. Risk factors: 3 patients were alcoholic, 4 patients were smokers, and 2 postpartum. A single patient with H1N1 required mechanical ventilation and died. Conclusion: pneumonia influenza (H1N1) can cause bilateral commitment, affect healthy patients at a younger age.