bluuebunny/crossref_metadata_2025 huggingface dataset:
Factors shaping network emergence: A cross-country comparison of quality of care networks in Bangladesh, Ethiopia, Malawi, and Uganda
Authors: Shawar Yusra Ribhi , Djellouli Nehla , Akter Kohenour , Payne Will , Kinney Mary , Mwaba Kasonde , Seruwagi Gloria , English Mike , Marchant Tanya ,   The QCN Evaluation Group, Shiffman Jeremy , Colbourn Tim
Published: July 2024

The Quality-of-Care Network (QCN) was conceptualized by the World Health Organization (WHO) and other global partners to facilitate learning on and improve quality of care for maternal and newborn health within and across low and middle-income countries. However, there was significant variance in the speed and extent to which QCN formed in the involved countries. This paper investigates the factors that shaped QCN’s differential emergence in Bangladesh, Ethiopia, Malawi, and Uganda. Drawing on network scholarship, we conducted a replicated case study of the four country cases and triangulated several sources of data, including a document review, observations of national-level and district level meetings, and key informant interviews in each country and at the global level. Thematic coding was performed in NVivo 12. We find that QCN emerged most quickly and robustly in Bangladesh, followed by Ethiopia, then Uganda, and slowest and with least institutionalization in Malawi. Factors connected to the policy environment and network features explained variance in network emergence. With respect to the policy environment, pre-existing resources and initiatives dedicated to maternal and newborn health and quality improvement, strong data and health system capacity, and national commitment to advancing on synergistic goals were crucial drivers to QCN’s emergence. With respect to the features of the network itself, the embedding of QCN leadership in powerful agencies with pre-existing coordination structures and trusting relationships with key stakeholders, inclusive network membership, and effective individual national and local leadership were also crucial in explaining QCN’s speed and quality of emergence across countries. Studying QCN emergence provides critical insights as to why well-intentioned top-down global health networks may not materialize in some country contexts and have relatively quick uptake in others, and has implications for a network’s perceived legitimacy and ultimate effectiveness in producing stated objectives.
Strong effect of demographic changes on Tuberculosis susceptibility in South Africa
Authors: Oyageshio Oshiomah P. , Myrick Justin W. , Saayman Jamie , van der Westhuizen Lena , Al-Hindi Dana R. , Reynolds Austin W. , Zaitlen Noah , Hoal Eileen G. , Uren Caitlin , Möller Marlo , Henn Brenna M.
Published: July 2024

South Africa is among the world’s top eight tuberculosis (TB) burden countries, and despite a focus on HIV-TB co-infection, most of the population living with TB are not HIV co-infected. The disease is endemic across the country, with 80–90% exposure by adulthood. We investigated epidemiological risk factors for (TB) in the Northern Cape Province, South Africa: an understudied TB endemic region with extreme TB incidence (926/100,000). We leveraged the population’s high TB incidence and community transmission to design a case-control study with similar mechanisms of exposure between the groups. We recruited 1,126 participants with suspected TB from 12 community health clinics and generated a cohort of 774 individuals (cases = 374, controls = 400) after implementing our enrollment criteria. All participants were GeneXpert Ultra tested for active TB by a local clinic. We assessed important risk factors for active TB using logistic regression and random forest modeling. We find that factors commonly identified in other global populations tend to replicate in our study, e.g. male gender and residence in a town had significant effects on TB risk (OR: 3.02 [95% CI: 2.30–4.71]; OR: 3.20 [95% CI: 2.26–4.55]). We also tested for demographic factors that may uniquely reflect historical changes in health conditions in South Africa. We find that socioeconomic status (SES) significantly interacts with an individual’s age (p = 0.0005) indicating that protective effect of higher SES changed across age cohorts. We further find that being born in a rural area and moving to a town strongly increases TB risk, while town birthplace and current rural residence is protective. These interaction effects reflect rapid demographic changes, specifically SES over recent generations and mobility, in South Africa. Our models show that such risk factors combined explain 19–21% of the variance (r2) in TB case/control status.
Assessing red blood cell distribution width in Vietnamese heart failure patients: A cross-sectional study
Authors: Dang Hai Nguyen Ngoc , Viet Luong Thang , Cao Mai Thi Thu , Bui Vinh Trung , Tran Thanh Thien , Nguyen Hung Minh
Published: July 2024

Background

Heart failure (HF) is becoming a growing public health concern. Diagnostic tests for determining the severity of HF often come with high costs and require specialized expertise, which makes it difficult to assess HF severity, especially in low-income countries or at primary healthcare facilities. Recently, red blood cell distribution width (RDW) has emerged as a promising, easily accessible marker associated with HF severity. The study aimed to assess changes in RDW levels in HF patients and the diagnostic value of RDW in detecting acute heart failure (AHF) among HF patients.

Methods

We conducted a cross-sectional examination involving 351 participants divided into HF and non-HF cohorts. HF was defined and categorized according to the diagnostic and treatment guidelines for AHF and chronic heart failure (CHF) set forth by the European Society of Cardiology (2021). Univariate and multivariate analysis of factors associated with AHF was performed.

Results

The study revealed that HF patients displayed higher median RDW levels (14.90% [13.70–17.00]) compared to non-HF individuals (13.00% [12.23–13.78]). RDW was notably elevated in HF patients with left ventricular ejection fraction < 50% compared to those with left ventricular ejection fraction ≥ 50%. ROC curve analysis of RDW for AHF detection identified a cutoff value of 13.85%, with a sensitivity of 86.05% and specificity of 47.18%, statistically significant at p < 0.001. RDW > 13.85% was identified as an independent risk factor for AHF in patients with HF, with odds ratios of 2.644 (95% CI, 1.190–5.875; p = 0.017).

Conclusion

The study revealed significant RDW variations in patients with CHF and AHF compared to the control group. These findings suggest that RDW could be a biomarker for detecting HF severity.
Thirty-day hospital readmission in females with acute heart failure and breast cancer: A retrospective cohort study from national readmission database
Authors: Kambalapalli Soumya , Baral Nischit , Paul Timir K. , Upreti Prakash , Talaei Fahimeh , Ayad Sarah , Ibrahim Mahmoud , Aggarwal Vikas , Kumar Gautam , Alraies Chadi , Mitchell Joshua
Published: July 2024

Background

Breast Cancer and cardiovascular diseases are amongst the two leading causes of mortality in the United States, and the two conditions are connected in part because of recognized cardiotoxicity of cancer treatments. The aim of this study is to investigate the predictors risk factors for thirty-day readmission in female breast cancer survivors presenting with acute heart failure.

Methods

This is a retrospective cohort study of acute heart failure (AHF) hospitalization in female patients with breast cancer in 2019 using the National Readmission Database (NRD), which is the largest publicly available all-payer inpatient readmission database in the United States. Our study sample included adult female patients aged 18 years and older. The primary outcome of interest was the rate of 30- day readmission.

Results

In 2019, there were 8332 total index admissions for AHF in females with breast cancer and 7776 patients were discharged alive. The mean age was 74.4 years (95% CI: 74, 74.7). The percentage of readmission at 30 days among those discharged alive was 21.8% (n = 1699). Hypertensive heart disease with chronic kidney disease accounted for the majority of readmission in AHF with breast cancer followed by sepsis, acute kidney injury, respiratory failure, pneumonia, and atrial fibrillation. Demographic factors including higher burden of comorbidities predict readmission. The total in-hospital mortality in index admission was 6.67% (n = 556) and for readmitted patients was 8.77% (n = 149). The mean length of stay for index admission was 7.5 days (95% CI: 7.25, 7.75).

Conclusions

Readmission of female breast cancer survivors presenting with AHF is common and largely be attributed to high burden of comorbidities including hypertension, and chronic kidney disease. A focus on close outpatient follow-up will be beneficial in lowering readmissions.
CFDMI-SEC: An optimal model for copy-move forgery detection of medical image using SIFT, EOM and CHM
Authors: Amiri Ehsan , Mosallanejad Ahmad , Sheikhahmadi Amir
Published: July 2024

Image forgery is one of the issues that can create challenges for law enforcement. Digital devices can easily Copy-move images, forging medical photos. In the insurance industry, forensics, and sports, image forgery has become very common and has created problems. Copy-Move Forgery in Medical Images (CMFMI) has led to abuses in areas where access to advanced medical devices is unavailable. The proposed model (SEC) is a three-part model based on an evolutionary algorithm that can detect fake blocks well. In the first part, suspicious points are discovered with the help of the SIFT algorithm. In the second part, suspicious blocks are found using the equilibrium optimization algorithm. Finally, color histogram Matching (CHM) matches questionable points and blocks. The proposed method (SEC) was evaluated based on accuracy, recall, and F1 criteria, and 100, 97.00, and 98.47% were obtained for the fake medical images, respectively. Experimental results show robustness against different transformation and post-processing operations on medical images.
Factors associated with non-specific low back pain in field hockey: A cross-sectional study of Premier and Division One players
Authors: Dobbin Nick , Getty Craig , Digweed Benn
Published: July 2024

Objective

To determine the extent to which various factors are associated with greater or lesser odds of reporting non-specific low back pain (NS-LBP) in field hockey.

Methods

To meet the objective of the study, a cross-sectional study design was used with a purposive sampling strategy. A total of 194 responses (~18% of those accessible) from Premier and Division One players within the UK were received using a UK-based online survey. Data collected included information on NS-LBP, participant characteristics, injury history, training related factors, and work and personal factors. The overall and category-specific prevalence of NS-LBP was calculated. Univariable and multivariable logistic regression was used in conjunction with clinical value to identify associations.

Results

The overall prevalence of NS-LBP was 44.0%, with this varying from 23.5 to 70.0% for categories with responses of “yes” and “no” to experiencing NS-LBP. A total of ten individual factors associated with a greater odds ratio (OR) of reporting NS-LBP (OR = 1.43–7.39) were identified in Premier and Division One players. Five individual factors were associated with reduced odds (OR = 0.11–0.60) of reporting NS-LBP. Seven factors (age, stature, playing position, playing internationally, performing a drag flick, low back stiffness/tightness and occupational factors) were deemed particularly pertinent to those working in field hockey given the magnitude of association and clinical value to clinicians.

Conclusions

Clinicians working in field hockey can consider the key risk factors identified in this study that are associated with NS-LBP when assessing injury risk, movement screening approaches, and overall athlete management.
Obesity-related cancer and bariatric surgery: A comprehensive systematic review and meta-analysis protocol
Authors: Feitosa Isadora de Albuquerque Falcão , de Souza Castro Caio Cesar , de Araújo André Igor Nogueira , Coutinho Bárbara Scarlett , Meneses do Rêgo Amália Cínthia , de Moura Santos Edilmar , de Medeiros Kleyton Santos , Araújo-Filho Irami
Published: July 2024

Introduction

Obesity is a silent pandemic affecting all ages and is a component of metabolic syndrome. Its treatment is conducted by lifestyle and behavioral changes, pharmacological therapy, and when correctly indicated, bariatric surgery. In recent years, the procedures for weight loss have been investigated due to their relationship with the development of many types of cancer. Although many studies have shown that bariatric surgery decreases cancer risk, other researchers observed an increase in this association. Carcinogenesis is affected by many factors, such as age, sex, type of cancer, and the bariatric surgery performed on each patient. This systematic review and meta-analysis protocol aims to clarify the association between the different modalities of bariatric surgery and the risk of cancer development in adult patients with metabolic syndrome.

Method and analysis

The proposed systematic review and meta-analysis will be reported conforming to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA-P) guidelines. This research will include observational studies (case-control and cohort studies) about patients who undergo bariatric surgery due to metabolic syndrome. Will be accepted in any language and any year. Publications without peer review will be excluded from this review. Data will be entered into the Review Manager software (RevMan5.2.3). We extracted or calculated the OR and 95% CI for dichotomous outcomes for each study. In case of heterogeneity (I2>50%), the random-effects model will combine the studies to calculate the OR and 95% CI.

Ethics and dissemination

This study will review the published data; Thus, obtaining ethical approval is unnecessary. The findings of this systematic review will be published in a peer-reviewed journal.

Prospero registration number

CRD42023432079.
Moving from stable standing to single-limb stance or an up-on-the-toes position: The importance of vision to dynamic balance control
Authors: Buckley John G. , Frost Sorcha-Sinead , Hartley Shaun , Rodacki Andre L. F. , Barrett Brendan T.
Published: July 2024

Understanding the contribution vision has to dynamic balance control may help in understanding where/why loss of balance occurs during everyday locomotion. The current study determined how body-centre-of-mass (BCoM) dynamics and postural stability when moving to and holding a single-limb-stance (SS) or an up-on-the-toes (UTT) position were affected by visual occlusion. From standing on a force platform, 18 adults (mean (SD) 26.7 (4.8) years; 1.73 (0.08) m; 84.0 (22.9) kg; 7 females) completed repeated trials (x3) with and without vision in which they moved to either a SS or an UTT position (order countered-balanced), and attempted to hold that position for 2 (SS) or 5 (UTT) seconds before returning to standing. UTT trials were also repeated at a fast speed, and SS trials were repeated using both the dominant and non-dominant limb. BCoM dynamics were assessed by analysing the displacement and peak velocity of the centre-of-pressure (CoP) when moving to and from the SS and UTT positions. Balance stability was the variability in the CoP displacement/velocity when holding these positions. Results indicate that under visual occlusion, the peak CoP velocity when moving to the SS or UTT position was reduced (ES, 0.67 and 0.68, respectively), suggesting greater caution. Both the variability in the CoP displacement/velocity when holding these positions and the peak CoP velocity when returning to flat-standing increased (SS: ES, 1.0 and 0.86, respectively; UTT: ES 1.26 and 0.66, respectively), suggesting, respectively, greater instability and poorer control. The poorer control in SS trials, occurred when returning to standing from the SS position held on the non-dominant limb, and correspondingly, the reduction in SS duration when vision was occluded was greater for the non-dominant limb trails (limb-vision interaction; p = 0.042). This suggests that movements initiated/controlled by the non-dominant limb are more reliant on visual feedback than those initiated/controlled by the dominant limb.
Integration of machine learning XGBoost and SHAP models for NBA game outcome prediction and quantitative analysis methodology
Authors: Ouyang Yan , Li Xuewei , Zhou Wenjia , Hong Wei , Zheng Weitao , Qi Feng , Peng Liming
Published: July 2024

This study investigated the application of artificial intelligence in real-time prediction of professional basketball games, identifying the variations within performance indicators that are critical in determining the outcomes of the games. Utilizing games data from the NBA seasons 2021 to 2023 as the sample, the study constructed a real-time predictive model for NBA game outcomes, integrating the machine learning XGBoost and SHAP algorithms. The model simulated the prediction of game outcomes at different time of games and effectively quantified the analysis of key factors that influenced game outcomes. The study’s results demonstrated that the XGBoost algorithm was highly effective in predicting NBA game outcomes. Key performance indicators such as field goal percentage, defensive rebounds, and turnovers were consistently related to the outcomes at all times during the game. In the first half of the game, assists were a key indicator affecting the outcome of the game. In the second half of the games, offensive rebounds and three-point shooting percentage were key indicators affecting the outcome of the games. The performance of the real-time prediction model for NBA game outcomes, which integrates machine learning XGBoost and SHAP algorithms, is found to be excellent and highly interpretable. By quantifying the factors that determine victory, it is able to provide significant decision support for coaches in arranging tactical strategies on the court. Moreover, the study provides reliable data references for sports bettors, athletes, club managers, and sponsors.
Acceleration of wound healing using adipose mesenchymal stem cell secretome hydrogel on partial-thickness cutaneous thermal burn wounds: An in vivo study in rats
Authors: Kuncorojakti Suryo , Pratama Awidhan Zainal Adi , Antujala Cahya Asri , Harijanto Clarence Theodosius Bernard , Arsy Rozak Kurnia , Kurniawan Putut Andika , Tjahjono Yudy , Hendriati Lucia , Widodo Teguh , Aswin Ahmad , Diyantoro Diyantoro , Wijaya Andi Yasmin , Rodprasert Watchareewan , Susilowati Helen
Published: July 2024

Background and Aim: The intricate healing process involves distinct sequential and overlapping phases in thermal injury. To maintain the zone of stasis in Jackson’s burn wound model, proper wound intervention is essential. The extent of research on the histoarchitecture of thermal wound healing and the application of mesenchymal stem cell (MSC)-free-based therapy is limited. This study aimed to assess the efficacy of MSC-secretome-based hydrogel for treating partial-thickness cutaneous thermal burn wounds.

Materials and Methods: Eighteen male Wistar rats were divided into three groups, namely the hydrogel base (10 mg), hydrogel secretome (10 mg) and Bioplacenton™ (10 mg) treatment groups. All groups were treated twice a day (morning and evening) for 7 days. Skin tissue samples from the animals were processed for histological evaluation using the formalin-fixed paraffin-embedded method on days 3 and 7.

Results: This study’s findings showed that secretome hydrogel expedited thermal burn wound healing, decreasing residual burn area, boosting collagen deposition and angiogenesis, guiding scar formation, and influencing the inflammation response facilitated by polymorphonuclear leukocytes and macrophages.

Conclusion: The secretome hydrogel significantly improves healing outcomes in partial-thickness cutaneous thermal burn wounds. The administration of secretome hydrogel accelerates the reduction of the residual burn area and promotes fibroblast proliferation and collagen density. The repairment of histo-architecture of the damaged tissue was also observed such as the reduction of burn depth, increased angiogenesis and epidermal scar index while the decreased dermal scar index. Furthermore, the secretome hydrogel can modulate the immunocompetent cells by decreasing the polymorphonuclear and increasing the mononuclear cells. Thus, it effectively and safely substitutes for thermal injury stem cell-free therapeutic approaches. The study focuses on the microscopical evaluation of secretome hydrogel; further research to investigate at the molecular level may be useful in predicting the beneficial effect of secretome hydrogel in accelerating wound healing.

Keywords: drug safety, mesenchymal stem cell-conditioned media, stem cell-free-therapy, thermal injury, wound healing.
Para pensar a relação entre migração, raça e corpo a partir de pensadores sociais brasileiros no final do século XIX e início do século XX.
Authors: Ennes Marcelo
Published: July 2024

O objeto do presente artigo são as relações entre os temas da imigração, da raça e do corpo em obras de autores brasileiros na passagem do século XIX e XX. O objetivo geral consiste em verificar como o corpo aparece no debate sobre imigração e raça entre os autores escolhidos. A motivação do estudo que deu origem ao artigo está relacionada ao crescimento do número de publicações e de referência ao corpo em estudos contemporâneos sobre imigração, tema que é parte de uma agenda maior de pesquisa e que será objeto de uma nova publicação. As reflexões que ora apresentamos foram desenvolvidas a partir da revisão bibliográfica realizada em duas frentes. A primeira consistiu na retomada de leituras de importantes obras e autores que se dedicaram a estudar por assim dizer os precursores do pensamento social no Brasil que abordaram o tema da formação do povo brasileiro no período aqui estudado. A segunda frente de trabalho consistiu na releitura de obras destes precursores agora confrontadas com a possível relação entre imigração, raça e corpo. Ao final, o artigo demonstra que o corpo apareça sobretudo a partir da ideia de raça e de sua interface com o debate sobre a formação do povo brasileiro no qual a miscigenação é o tema medular. Neste contexto, raça e, indiretamente o corpo, é central tanto para autores que destacam aspectos genéticos e biológicos quanto para os que defendem a perspectiva culturalista.
Sociologia Modernista e Cultura Historiográfica: tempo e sociedade nas primeiras décadas do século XX
Authors: Lara Martins Maro
Published: July 2024

A partir do diálogo entre história e sociologia, este artigo procura as matrizes da interpretação do Brasil a partir do ensaio e do ensaísmo dos anos 1930 no país, revelando os modos pelos quais o diagnóstico da Modernidade Patológica se estabeleceu como ponto de partida para os intelectuais brasileiros daquele período. De um lado a sociologia modernista, que emerge do modernismo. Investiga-se a composição das interpretações historiográficas, fruto da cultura historiográfica, e da consciência sociológica, que emerge do nascente modernismo brasileiro, de outro, a maturação de uma cultura historiográfica nacional que vinha se afirmando desde o final do século XIX. Ambas, produzidas indistintamente nas mãos de intelectuais polígrafos, pouco afeitos às divisões disciplinares.
A Resiliência da Identidade: Indigenato e a Virada Histórica no Direito Internacional
Authors: Lixinski Lucas
Published: July 2024

Neste artigo, eu discuto a falta de narrativas centradas na perspectiva indígena na virada histórica no direito internacional. Considerando-se que um dos principais usos políticos desta virada histórica visa desfazer os danos dos encontros coloniais (como nas Abordagens Terceiro-Mundistas de Direito Internacional, por exemplo), é um tanto quanto consternante que frequentemente, e particularmente em contextos indígenas, estes encontros  ainda são contados a partir da perspectiva do colonizador. Assim, a existência indígena é concebida unicamente da perspectiva de vitimização, que é inevitavelmente articulada de uma forma que nega agência às pessoas e povos indígenas como atores históricos. Este paradoxo demonstra a resiliência do eurocentrismo na nossa articulação de projetos jurídicos internacionais, e a resiliência da identidade e resistência indígenas apesar de seu apagamento estrutural ainda em andamento. Este artigo portanto pergunta o que pode significar, epistemologicamente e metodologicamente, centralizar o indigenato na virada histórica do direito internacional, argumentando-se pela recuperação e alavancamento da agência indígena na virada histórica no direito internacional. Eu, pessoalmente, não sou indígena, portanto eu não viso oferecer uma “visão indígena da história do direito internacional”, mas sim simplesmente criar e explorar cunhas na produção acadêmica voltada à virada histórica. Estas cunhas podem tornar o campo mais receptivo a atender à resiliência do subalterno, abrir o campo para metodologias históricas alternativas e questionar fundamentalmente se nós podemos aprender sobre a resiliência face aos desafios externos ao ordenamento jurídico internacional a partir da resiliência já existente no direito internacional.
Estados vs. Povos. Premissas e tentativas de construção de uma ciência do direito internacional na primeira metade do Século XIX
Authors: Storti Claudia
Published: July 2024

A reconstrução histórica dos debates nas doutrinas de direito internacional do século XIX enquanto ciência “nova” que se debruça sobre a própria essência desse ramo do direito na tentativa de fornecer novos paradigmas para o entendimento dos seus sujeitos, das relações entre eles, e das suas fontes, transcendendo aos seculares postulados até então em vigor, é o objetivo desse artigo. Para tanto, a análise ao longo do texto tenta responder três questões, ou seja: porque no século XIX, na Europa e nos Estados Unidos, se manifesta a exigência de legitimar com base científica “as” regras universais nas relações entre os estados e entre os estados e os “povos” como vinculantes e superiores ao direito convencional e positivo? Em que sentido foi entendida a expressão “ciência do direito internacional” e qual foi a função atribuída a tal ciência? Existia um background cultural e científico que condicionou as características e os elementos das várias tentativas de construção científica?
Review of clinical practice guidelines for hypoparathyroidism
Authors: Kovaleva E. V. , Eremkina A. K. , Maganeva I. S. , Mirnaya S. S. , Kim I. V. , Kuznetzov N. S. , Andreeva E. N. , Karonova T. L. , Kryukova I. V. , Mudunov A. M. , Sleptcov I. V. , Melnichenko G. A. , Mokrysheva N. G.
Published: July 2024

Hypoparathyroidism is an endocrine disease characterized by reduced production of parathyroid hormone by the parathyroid glands or tissue resistance to its action. This is accompanied by disturbances in phosphorus-calcium metabolism.

The main cause of hypoparathyroidism is damage or removal of the parathyroid glands during surgery on the neck organs. Autoimmune hypoparathyroidism is the second most common form of the disease, which occurs, as a rule, within the autoimmune polyglandular syndrome type 1.

The development of chronic hypoparathyroidism of any etiology requires lifelong appointment of multicomponent therapy, as well as careful monitoring and an individual approach. In the absence of adequate dynamic monitoring, multiple complications develop from vital organs, in particular calcification of the urinary system, soft tissues and the brain; cardiovascular pathology; visual disturbances; muscle and bone diseases leading to decreased quality of life of patients.

Thus, timely diagnosis, rationally selected drug therapy and competent patient management will reduce the risks of complications, improve the prognosis, and reduce the frequency of hospitalizations and disability of patients with chronic hypoparathyroidism.

The article presents the main recommendations of the new project of clinical guidelines for patients with hypoparathyroidism, approved by the Ministry of Health of the Russian Federation in 2021. They include the algorithms of diagnosis, treatment and dynamic monitoring of hypoparathyroidism, as well as management of postsurgical hypocalcemia and medical care of and the disease during pregnancy.
Halal Tourism in West Sumatera: a Bibliometric Study
Authors: Mardian Sepky , Armen Rio Erismen
Published: July 2024

West sumatera is a halal tourism destination in Indonesia. It was acknowledged by Global Muslim Travel Index in 2016. All stakeholders have given more intention to this halal tourism. Beyond the strengthening district regulation on it, the studies on halal tourism in West Sumatera have been increasing every year. This study aims to map the research about halal tourism in West Sumatera. Bibliometric approach was conducted to map the different studies on this topic. By using Publich or Perish, the data were taken from Google Scholar database. Several keywords were used to do it, i.e. halal tourism in West Sumatera, Islamic tourism in West Sumatera, wisata halal di Sumatera Barat and wisata Sariah di Sumatera Barat. The metadata were described by tables and graphs. Again it is also visualized by VOSViewer to find the research cluster on the topic and trend of relationship among the keywords. The study found that the research on Islamic tourism in West Sumatera is still limited. It only found 35 journal articles or proceeding in tens of years. The theme is also limited on description of the opportunity and challenges and stakeholders perception about Islamic tourism in West Sumatera.
Peranan pertumbuhan ekonomi dalam memediasi faktor-faktor yang mempengaruhi indeks pembangunan manusia
Authors: Susila Muktar Redy
Published: July 2024

Provincial HDI data in 2022 shows striking disparities between regions. This figure shows the uneven economic development in Indonesia. An analysis of factors that can influence HDI is needed. This research aims to analyze the influence of regional finan-cial performance and capital expenditure on HDI with economic growth as an inter-vening variable. The sample used in this research was 34 provinces that met the research criteria. The variables used in this research are regional financial performance, capital expenditure, economic growth, and HDI. Financial performance and capital expenditure are exogenous variables, economic growth is an intervening variable, and HDI is an endogenous variable. The method used to analyze the relationship between variables is SEM PLS. The test results show that financial performance, capital expenditure and economic growth directly have a positive significant effect on HDI. The results of this test have the implication that to improve the quality of life of the population, attention is needed to improve financial performance, capital expenditure and economic growth in each region. The other test results showed that economic growth was able to mediate the effect of capital expenditure on HDI but was not able to mediate the effect of financial performance on HDI.
Common Fixed Point Theorems in Extended Rectangular b-Metric Spaces
Authors: Rakesh Tiwari  , Rajesh Patel Rajesh Patel
Published: July 2024

In this paper, we establish common fixed point theorems for quadruple weakly compatible mappings satisfying a new generalized contraction condition. Our results generalize the corresponding result of Budi Nurwahyu et al. [6]. Non-trivial examples are further provided to support the hypotheses of our results.
Impact of relative humidity on SARS-CoV-2 RNA extraction using Nextractor automated extraction system
Authors: Jain Rajeev Kumar , Sharma Archa , Lalwani Jaya , Chaurasia Deepti , Perumal Nagaraj
Published: July 2024

This study investigated the influence of relative humidity (RH) on the efficiency of SARS-CoV-2 RNA extraction using the Nextractor automated system. Experiments employing clinical samples demonstrated satisfactory sensitivity and reproducibility for RNA extraction at low humidity (below 50% RH). Conversely, extractions at high humidity (above 70% RH) resulted in complete failure of reverse transcription-polymerase chain reaction assays, with neither SARS-CoV-2 RNA nor the human RNase P gene (internal control) detected. Analysis suggested that residual ethanol, incompletely evaporating due to high humidity, acted as a potent polymerase chain reaction inhibitor in these samples. These findings highlighted the importance of maintaining optimal laboratory humidity (<50% RH) for reliable SARS-CoV-2 RNA extraction using the Nextractor system. Furthermore, laboratories should implement strategies such as regular humidity monitoring, staff training on humidity’s impact, and system validation under specific humidity conditions to ensure accurate molecular diagnostic workflows for COVID-19 testing.
Calcium chloride and arginine show diametrically opposite effects on antibody elution in Protein A and Protein L chromatography
Authors: Qu Ju , Wan Yan , Li Yifeng
Published: July 2024

Protein A and Protein L affinity chromatographies are extensively used in mAb and bispecific antibody (bsAb) purification. In addition to product capture, they are both capable of separating certain product-related by-products and aggregates under appropriate conditions. For both types of chromatography, previous studies suggested that adding a salt additive to the mobile phase can significantly improve the resolution between product and by-products/aggregates. Nevertheless, the effects of different salt additives on antibody elution in Protein A and Protein L chromatography have not been compared. In the current study, we compared the effects of three salt additives, sodium chloride (NaCl), calcium chloride (CaCl2), and arginine hydrochloride (Arg·HCl), on antibody elution in Protein A and Protein L chromatography. Interestingly, while NaCl suppressed antibody elution in both types of chromatography, CaCl2, and Arg·HCl promoted antibody elution in Protein A chromatography but suppressed antibody elution in Protein L chromatography. In addition, we evaluated the effect of each salt gradient on aggregate removal by Protein L chromatography. The information provided by the current study should be useful to the selection of conditions/additives for improving by-product removal by Protein A and Protein L chromatography.
El cuerpo en la salud mental y la salud mental en el cuerpo: apuntes desde una antropología corporizada de la salud (mental)
Authors: Betancur Alvarado Pablo
Published: July 2024

Este artículo, a partir de una revisión de tema devenida del marco teórico construido para mi trabajo tesis de maestría, busca entregar insumos teórico-conceptuales y metodológicos desde la antropología y las ciencias sociales, para la comprensión de las experiencias encarnadas/corporizadas de las/os usuarias/os de la salud mental, en tanto uno de los fenómenos contemporáneos más relevantes a la hora de problematizar el cuerpo en las sociedades contemporáneas. Para construir tal propuesta, transito por los campos de la antropología del cuerpo, la antropología desde el cuerpo y la antropología médica, situando el entendimiento de la salud, la salud mental y el cuerpo. Finalizo con la construcción de una perspectiva que he denominado antropología corporizada de la salud (mental), la que, más que una propuesta nueva, sintetiza caminos ya recorridos, siempre sujeto a revisión y corrección.
En tiempo presente: El giro femenino en Colombia. Dejar atrás el conflicto armado experienciando el sentir, para ir tras las huellas que convocan el re-vivir.
Authors: Montoya Rivera Magda Irene , Conde Rivera Gaviota Marina
Published: July 2024

Este artículo abre la reflexión sobre el lugar de quienes narran la historia de opresión de  las mujeres en Colombia alrededor del conflicto armado, en su condición de víctimas  de un sistema patriarcal que se ha valido de la violencia, la fuerza  y el despojo, para someter a través de  prácticas de guerra que se ensañan contra sus corporalidades. Trascender el conflicto y avanzar hacia la libertad y las capacidades que promueven el buen y el saber vivir como una apuesta re-existente y decolonial, obliga a pensarse en la ruta propuesta desde un giro femenino que en tiempo presente, posibilite validar un modo alterno de resignificar las vidas femeninas, considerando factores externos  político-económicos y modos de relacionamiento socio-cultural, pero en especial, mediante la vinculación de prácticas que desde el ser, a través del cuerpo, lo estético y lo sensible, posibiliten experienciar y concienciar lo vivido, para repararse en dignidad y cuidado de la vida.
Toponimi Desa-Desa di Kecamatan Pucakwangi Kabupaten Pati (Kajian Antropolinguistik)
Authors: Gusmiarnum Genisti Arselia , Suyanto Suyanto
Published: July 2024

Penelitian ini bertujuan untuk mengidentifikasi satuan lingual nama desa-desa dan menjelaskan aspek-aspek toponimi di Kecamatan Pucakwangi. Penelitian ini dianalis dengan teori antropolinguistik, toponimi, dan satuan lingual kata. Penelitian ini adalah penelitian deskriptif kualitatif. Dalam pengumpulan data digunakan metode observasi, wawancara, dan studi pustaka dengan teknik pancing, simak libat cakap, dan rekam catat. Dalam analisis data digunakan metode padan dan distribusional dengan teknik reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan satuan lingual nama desa di Kecamatan Pucakwangi berbentuk kata melalui proses morfologis afiksasi, abreviasi, dan komposisi. Aspek-aspek toponimi dalam 20 desa di Kecamatan Pucakwangi diklasifikasikan menjadi tiga, yaitu 15 aspek perwujudan, 9 aspek kemasyarakatan, dan 10 aspek kebudayaan. Toponimi desa di Kecamatan Pucakwangi berkaitan dengan nilai mitologis tentang adanya lautan di beberapa desa yang merujuk pada fakta-fakta sejarah Selat Muria purba.Kata Kunci : Antropolinguistik, toponimi, satuan lingual, kearifan lokal, Selat Muria Purba.
Inkonsistensi Fitur Kebahasaan pada Kaum Gay dalam Kanal Langit Entertainment
Authors: Al Fiansyah Muhammad Azmi , Arimi Sailal
Published: July 2024

Penelitian ini bertujuan untuk menjelaskan fitur kebahasaan yang digunakan oleh kaum gay dan faktor sosial apa yang mempengaruhinya. Penelitian ini menggunakan metode kualitatif dengan data berupa video dari kanal Langit Entertaiment yang berjudul “KITA G4Y KARENA TRAUMA, BUKAN PILIHAN! SUATU SAAT KITA PENGEN PUNYA KETURUNAN!”. Data dianalisis menggunakan teori Lakoff tentang fitur kebahasaan perempuan. Hasil penelitian menunjukkan bahwa empat dari lima gay yang diwawancarai tetap menggunakan fitur kebahasaan laki-laki, namun menggunakan intonasi naik seperti fitur kebahasaan perempuan. Penelitian ini menyimpulkan bahwa fitur kebahasaan dipengaruhi oleh faktor sosial seperti pelecehan, seksual, atau lingkungan yang feminim. Fitur kebahasaan juga tidak bisa dipaksakan, seperti dalam contoh data yang ditemukan, mereka tetap menggunakan fitur laki-laki, namun intonasinya saja yang seperti fitur kebahasaan perempuan. Penelitian ini diharapkan dapat berkontribusi dalam ranah bahasa dan gender kedepannya.
Implikatur Percakapan dan Pelanggaran Prinsip Kerja Sama dalam Novel Kisah untuk Geri Karya Erisca Febriani
Authors: Adji Beryl Septiani , Indrastuti Novi Siti Kussuji
Published: July 2024

Tenang Saja, Allah akan Menjaga Kita! adalah buku cerita anak karya Tim Muhajir Project yang diterbitkan pada tahun 2022. Penelitian ini menganalisis lima dimensi religiositas yang muncul dalam buku cerita anak ini dengan menggunakan teori Glock dan Stark yang dilengkapi oleh Ancok dan Suroso. Analisis lima dimensi religiositas dalam buku anak ini dimaksudkan untuk mengungkap sejauh mana dimensi religiositas yang diperlihatkan dalam cerita untuk menanamkan nilai moral pada pembacanya. Metode yang digunakan adalah metode deskriptif-kualitatif dengan buku anak Tenang Saja, Allah akan Menjaga Kita!sebagai sumber data primer. Hasil penelitian menemukan bahwa buku anak ini memiliki lima dimensi religiositas yang digunakan untuk memberi pembelajaran dan contoh dalam beragama, khususnya terkait iman kepada Allah SWT., kepada para pembacanya yang masih anak-anak. Kelima dimensi religiositas ini tidak berdiri sendiri, melainkan saling berkaitan dengan satu sama lain. Kelima dimensi religiositas itu adalah (1) dimensi keyakinan, (2) dimensi praktik, (3) dimensi pengalaman, (4) dimensi pengetahuan agama, dan (5) dimensi pengalaman religius. Kata Kunci: Sastra Anak, Dimensi Religiositas, Cerita Anak Islami
Implikatur Percakapan dan Pelanggaran Prinsip Kerja Sama dalam Novel "Kisah untuk Geri" Karya Erisca Febriani
Authors: Ananda Shafinna Wahyu , Astuti Sri Puji
Published: July 2024

Penelitian ini bertujuan mendeskripsikan implikatur percakapan dan pelanggaran prinsip kerja sama yang terdapat dalam percakapan antartokoh dalam novel Kisah untuk Geri karya Erisca Febriani. Teori yang digunakan adalah teori pragmatik. Metode pengumpulan data yang digunakan adalah metode simak dengan teknik simak bebas libat cakap dan teknik catat. Metode analisis data yang digunakan adalah metode padan dengan menggunakan teknik daya pilah pragmatis. Penyajian hasil analisis data yang digunakan berupa penjelasan deskriptif secara informal. Hasil penelitian mengungkapkan bahwa di dalam percakapan antartokoh novel Kisah untuk Geri terdapat percakapan yang mengandung implikatur percakapan dengan sembilan macam maksud tuturan. Dalam penggalan percakapan antara tokoh dalam novel tersebut ditemukan juga pelanggaran prinsip kerja sama terkait empat maksim, yaitu maksim kuantitas, maksim kualitas, maksim relevansi, dan maksim pelaksanaan.Kata kunci: pragmatik, implikatur percakapan, pelanggaran prinsip kerja sama, tujuan tuturan, Kisah untuk Geri
Thermal mapping: Assessing the optimal sites for temperature measurement in the human body and emerging technologies
Authors: Yu L. , Delgado J. , De Mezerville R.
Published: July 2024

Numerous body locations have been utilized to obtain an accurate body temperature. While some are commonly used, their accuracy, response time, invasiveness varies greatly, and determines their potential clinical and/or research use. This review discusses human body temperature locations, their accuracy, ease of use, advantages, and drawbacks. We explain the concept of core body temperature and which of the locations achieve the best correlation to this temperature. The body locations include axilla, oral cavity, rectum, digestive and urinary tracts, skin, tympanic, nasopharynx, esophagus, and pulmonary artery. The review also discusses the latest temperature technologies, heat‐flux technology and telemetric ingestible temperature pills, and the body locations used to validate these devices. Rectal and esophageal measurements are the most frequently used.
4D ultrasound‐based strain assessment of cardiac dysfunction in male rats with reperfused and nonreperfused myocardial infarction
Authors: Omoto Ana C. M. , Earl Conner C. , Richards Alyssa M. , Annamalai Karthik , Nelson Benjamin , Hall John E. , Goergen Craig J. , da Silva Alexandre A.
Published: July 2024

Two‐dimensional ultrasound (2DUS) echocardiography is the main noninvasive method used to evaluate cardiac function in animal models of myocardial infarction (MI). However, 2DUS echocardiography does not capture regional differences in cardiac contractility since it relies on planar images to estimate left ventricular (LV) geometry and global function. Thus, the current study was designed to evaluate the efficacy of a newly developed 4‐dimensional ultrasound (4DUS) method in detecting cardiac functional differences between two models of MI, permanent ligation (PL), and ischemia/reperfusion (I/R) in rats. We found that only 4DUS was able to detect LV global functional differences between the two models and that 4DUS‐derived surface area strain accurately detected infarcted regions within the myocardium that correlated well with histological infarct size analysis. We also found that 4DUS‐derived strain, which includes circumferential, longitudinal, and surface area strain, correlated with the peak positive of the first derivative of left ventricular pressure (+dP/dtmax). In conclusion, 4DUS strain echocardiography effectively assesses myocardial mechanics following experimentally induced ischemia in rats and accurately estimates infarct size as early as 1 day after injury. 4DUS also correlates well with +dP/dtmax, a widely used marker of cardiac contractility.
Association between rat decompression sickness resistance, transthyretin single nucleotide polymorphism, and expression: A pilot study
Authors: Orsat J. , Guernec A. , Le Maréchal C. , Pichereau V. , Guerrero F.
Published: July 2024

Decompression sickness (DCS) is a systemic syndrome that can occur after an environmental pressure reduction. Previously, we showed that the plasmatic tetrameric form of transthyretin (TTR) nearly disappeared in rats suffering DCS but not in asymptomatic ones. In this pilot study, we assessed whether the resistance to DCS could be associated with polymorphism of the gene of TTR. For this study, Sanger sequencing was performed on purified PCR products from the liver of 14‐week‐old male and female standard and DCS‐resistant rats (n = 5 per group). Hepatic TTR mRNA expression was assessed by RT‐qPCR in 18–19 week‐old male and female standard and resistant rats (n = 6 per group). There is a synonymous single nucleotide polymorphism (SNP) on the third base of codon 46 (c.138 C > T). The thymine allele was present in 90% and 100% of males and females standard, respectively. However, this allele is present in only 30% of DCS‐resistant males and females (p = 0.0002301). In the liver, there is a significant effect of the resistance to DCS (p = 0.043) and sex (p = 0.047) on TTR expression. Levels of TTR mRNA were lower in DCS‐resistant animals. To conclude, DCS resistance might be associated with a SNP and a lower expression of TTR.
Parmenides and the Origins of the Heavenly Sphere in Ancient Greek Cosmology
Authors: Kočandrle Radim
Published: July 2024

Aristotle presented an influential conception of the universe consisting of a sphere of fixed stars with a spherical Earth at its centre. A spherical conception of heaven and Earth appears also in Plato’s writings. In presocratic cosmology, the idea of a spherical universe appears probably first in the thoughts of the Pythagoreans and Parmenides. But while there is no surviving evidence for the cosmology of early Pythagoreans, various sources mention in relation to Parmenides a solid surrounding part and a spherical Earth at the centre of the universe. Being, which Parmenides had likened to a sphere, may have moreover in a cosmological sense referred to ‘heaven.’ Furthermore, we can observe in presocratic cosmologies a development which shows that the cosmology of heavenly sphere appeared in the fifth century BCE. Although Parmenides is commonly thought to have influenced especially ontology, one can argue that it was he who introduced the concept of a heavenly sphere to cosmology, a notion which in Aristotle’s thought evolved into the notion of a sphere of fixed stars forming the boundary of the world.